cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Building efficient stated choice design for departure time choices using the scheduling model
Creators: name: Thorhauge, Mikkel
name: Cherchi, Elisabetta
name: Rich, Jeppe
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2014

description: Modelling departure time is an important step in forecasting traffic demand. The purpose of this research is to contribute to the data collection field when studying departure time choices. Differently from the majority of the previous studies we used an efficient stated preference (SP) experiment. The objective in an efficient design is to construct a stated preference experiment which minimizes the standard errors of the estimated parameter in the model. Thus, the benefits of using an efficient design are more robust parameter estimates and/or that it allows using smaller sample sizes. However, building experimental designs for the departure time is challenging for two main reasons: 1) interdependence among attributes, and 2) realism in the choice tasks. To ensure realism, we customized the choice task based on the trips described by each individual in a trip diary and on the departure time needed in order to be at work at their preferred arrival time. However, with efficient designs it is not possible to customize the SP for each individual, unless the real trips are known before optimizing the SP design. To overcome this challenge, six different designs were constructed based on predefined travel times (10, 20, 30, 40, 50, and 60 minutes). Respondents were presented with the design which was closest to their reported travel time in the trip diary. The design was simulated using almost 20.000 observations, and was adjusted until the design was stable and the prior parameters could be recuperated.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol 1 Nr 1 (2014): Proceedings from the Annual Transport Conference at Aalborg University
Development of pyrrolidine and isoindoline derivatives as new DPP8 inhibitors using a combination of 3D-QSAR technique, pharmacophore modeling, docking studies, and molecular dynamics simulations
Creators: name: Kaviani, Bita
name: Samani, Mojtaba Asad
name: Haghshenas, Hamed
name: Dehkordi, Marzieh Ghani
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer

description: Dipeptidyl peptidase proteins (DPPs) are a family of serine proteases with an active, vital role in multiple pathological conditions, including different types of cancer and autoimmune diseases. DPP inhibitors can induce an inflammatory form of cell death by activating inflammasome sensors and pro-caspase 1. This study used docking calculations and extended molecular dynamics simulations to investigate the interaction patterns for DPP8-inhibitor complex structures. We also implemented a novel procedure to develop new DPP8 inhibitors using pharmacophore and CoMFA models, docking studies, and molecular dynamics simulations. Our results showed the critical role of Glu 275, Glu 276, and Tyr 788 residues in the active site of protein in DPP8-inhibitor interaction. We also provided a platform for comparing the effectiveness of the most important DPP8 inhibitors. Moreover, we introduced a new 1G244 derivative with the highest affinity among all the studied compounds to inhibit DPP8 protein.
Quantum information processing with superconducting circuits: a review
Creators: name: Wendin, G.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: During the last ten years, superconducting circuits have passed from being interesting physical devices to becoming contenders for near-future useful and scalable quantum information processing (QIP). Advanced quantum simulation experiments have been shown with up to nine qubits, while a demonstration of Quantum Supremacy with fifty qubits is anticipated in just a few years. Quantum Supremacy means that the quantum system can no longer be simulated by the most powerful classical supercomputers. Integrated classical-quantum computing systems are already emerging that can be used for software development and experimentation, even via web interfaces. Therefore, the time is ripe for describing some of the recent development of superconducting devices, systems and applications. As such, the discussion of superconducting qubits and circuits is limited to devices that are proven useful for current or near future applications. Consequently, the centre of interest is the practical applications of QIP, such as computation and simulation in Physics and Chemistry.
description: 108 pages, 31 figures, 550 refs., review article
Migrants’ Community Participation and Social Integration in Urban Areas: A Scoping Review Protocol
Creators: name: Zhang, Yixin
name: Prachi Pundir
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Public Affairs, Public Policy and Public Administration
subject: Demography, Population, and Ecology
subject: Urban Studies
subject: Community Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: Sociology
subject: FOS: Sociology
subject: Civic and Community Engagement
subject: community participation
subject: migrants
subject: social integration
subject: urban areas

description: This scoping review aims to ascertain how migrants in urban areas achieve social integration through community participation. The main research question is: What is known from the previous literature about the influence of migrants’ community participation on their social integration in urban areas?
Modellering af kø-opstuvning i en statisk rutevalgsmodel
Creators: name: Hansen, Christian Overgård
name: Filges, Dorte
name: Sørensen, Henning
name: Brun, Bjarke
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2014

description: Artiklen beskriver forbedring til de statiske rutevalgsmodeller, som anvendes i Landstrafikmodellen (LTM) og OTM, så de bedre kan håndtere trængsel i vejnettet. Trængsel opstår typisk som følge af flaskehalse i vejnettet eksempelvis ved tilkørselsrampe på motorvej eller kryds i byen. I takt med stigende trafik bliver det derfor mere påkrævet, at trafikmodellerne kan belyse konsekvenserne i forhold til eksisterende og fremtidige flaskehalse. Der foreslås en metode, som umiddelbart kan integreres med de nuværende rutevalgsmodeller i LTM og OTM. De nuværende speed-flow kurver udbygges med kø-ventetidsfunktioner, som anvendes udover kapacitetsgrænsen. Kø-ventetidsfunktionerne, som beskriver middelventetid i kø pr. køretøj, er estimeret ved hjælp af kø-teori og verificeret mod aktuelle rejsetidsmålinger. Derudover introduceres reduktionsfaktorer for at kunne håndtere multiple flaskehalse i vejnettet, som er mere eller mindre indbyrdes afhængige. Metoden er succesfyldt testet i Hovedstadsområdet. Det er således muligt at identificere eksisterende flaksehalse og beregne køretider i myldertid svarende til rejsetidsmålinger. Det anbefales at arbejde videre med henblik på implementering i LTM.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol 1 Nr 1 (2014): Proceedings from the Annual Transport Conference at Aalborg University
Evaluation of bipartite entanglement between two optical multi-mode systems using mode translation symmetry
Creators: name: Wu, Jun-Yi
name: Hofmann, Holger F.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Optical multi-mode systems provide large scale Hilbert spaces that can be accessed and controlled using single photon sources, linear optics and photon detection. Here, we consider the bipartite entanglement generated by coherently distributing $M$ photons in $M$ modes to two separate locations, where linear optics and photon detection is used to verify the non-classical correlations between the two $M$-mode systems. We show that the entangled state is symmetric under mode shift operations performed in the two systems and use this symmetry to derive correlations between photon number distributions detected after a discrete Fourier transform (DFT) of the modes. The experimentally observable correlations can be explained by a simple and intuitive rule that relates the sum of the output mode indices to the eigenvalue of the input state under the mode shift operation. Since the photon number operators after the DFT do not commute with the initial photon number operators, entanglement is necessary to achieve strong correlations in both the initial mode photon numbers and the photon numbers observed after the DFT. We can therefore derive entanglement witnesses based on the experimentally observable correlations in both photon number distributions, providing a practical criterion for the evaluation of large scale entanglement in optical multi-mode systems. Our method thus demonstrates how non-classical signatures in large scale optical quantum circuits can be accessed experimentally by choosing an appropriate combination of modes in which to detect the photon number distributions that characterize the quantum coherences of the state.
description: 26 pages, 4 figures; This is the published version with the amended introduction, explanations of equations and conclusion
Optimization of bio based glass polyfurfuryl alcohol prepreg for composite applications
Creators: name: Odiyi, Daniel
Publisher: name: University of Derby
Year: 2023
Subjects: Biobased composites
Sustainable composite
Polyfurfuryl Alcohol resin

description: Global sustainability and emissions concerns in the manufacture and application of fibre composites have recently fueled research and development of bio-based alternatives to mitigate these challenges. One such material that has been developed and recently explored for composites applications is bio-based polyfurfuryl alcohol resin. It has demonstrated impressive mechanical and thermal properties in fibre applications. However, this comes with a major disadvantage of the long processing time, which for its manufacture is synonymous with manufacturing processes such as oven or autoclave curing, which limits its application for high volume production. To this end, this project aims to optimize the curing cycle of the glass / PFA prepreg for rapid manufacturing. Model-free and model-based kinetic studies were performed to understand the curing mechanism that occurs during the curing reaction. The Friedman and Ozawa-Flynn wall models were used to investigate the conversion-dependent activation energy. Both methods found that the average activation energy for the curing process was 88.9 ± 4.9 kJ/mol and further revealed a curing mechanism with a multi-step curing reaction consisting of parallel and competing reactions taking place simultaneously during the reaction. This was found to be relatively consistent with that obtained by the Kamal-Sourour fitted model. The excellent correlation between the Friedman model and the experimental data made it suitable for predicting the evolution of the reaction time under isothermal conditions, leading to an optimization of the total process cycle time from the manufacturer's recommended cycle of 113 minutes to 30 minutes when held isothermally at 160℃. Thus, suggestively making it suitable for rapid manufacturing processes such as the compression moulding process. Mechanical and thermal characterization was performed on Glass/PFA laminate manufactured by a hot press using the optimized cycle from the kinetic study at two different pressure (5 and 10bars) and this was benchmarked against laminates manufactured by the vacuum bagging - oven curing method using the manufacturer’s recommended cycle. The experimental results reveal that the cured glass/PFA laminate manufactured using the optimized cycle at 5 bar pressure was found to exhibit the best result showing an increase in the glass transition temperature (Tg) from 175℃ to 201℃. The impact of the optimized cure parameters on the mechanical properties of the glass/PFA composite was significant. It resulted in a notable 10.25% improvement in tensile strength, a substantial 13.04% increase in flexural strength, and a commendable 10.34% enhancement in apparent shear strength compared to the reference oven-cured glass/PFA sample. This successful study has effectively established the ideal cure parameters for the glass/PFA prepreg, enabling rapid and efficient composite fabrication.
Kombinatorische Entwicklung chiraler Bispidin-Liganden für die asymmetrische Katalyse
Creators: name: Huttenloch, Oliver
Publisher: name: Universität Dortmund
Year: 2001
Subjects: subject: Bispidine
subject: Asymmetrische Katalyse
subject: Kombinatorische Chemie
subject: Konjugierte Addition
subject: Polymer gebundene Liganden
subject: bispidines
subject: asymmetric
subject: catalysis
subject: combinatorial chemistry
subject: conjugate addition
subject: polymer supported ligands
subject: 540

description: Im Rahmen dieser Dissertation konnten verschiedene Derivate des Bispidins (3,7-Diazabicylo[3.3.1]nonan) hergestellt und als chirale Liganden in katalytischen, asymmetrischen Transformationen untersucht werden. Das Hauptaugenmerk lag dabei auf der Übertragung dieses gesamten Prozesses in ein kombinatorisches Format am polymeren Träger, um so einen effizienten Zugang zu neuen Bispidin-Phosphoramidit-Liganden für die enantioselektive konjugierte Addition von Kohlenstoff-Nukleophilen an Enone zu schaffen.Verschiedene Effekte herrührend von der Anbindung des Ligandensystems an einen polymeren Träger waren im Rahmen der Entwicklung einer Optimierungsstrategie zu berücksichtigen. Nach der Anpassung einiger Parameter gelang der Nachweis der Übertragbarkeit der Eigenschaften von festphasengebundenen Liganden auf ihre löslichen Analoga. Dies ermöglichte zum einen die sehr vorteilhafte kombinatorische Herstellung einer Ligandenbibliothek am polymeren Träger. Zum anderen konnten solche Liganden ohne Abspaltung von der festen Phase als Katalysatoren in der enantioselektiven konjugierten Addition von Dialkylzink-Reagenzien an Enone eingesetzt werden. Diese beiden Tatsachen ermöglichten die effiziente Optimierung der 'Leitstruktur' der Bispidin-Phosphoramidite. Abschließend konnten solche, verbesserte Liganden in löslicher Form synthetisiert und erfolgreich in der oben genannten Reaktion angewendet werden.Zusammenfassend konnte somit ein deutlich verbessertes Bispidin-Ligandensystem mit Pivaloyl-Rest und Dimethyl-BINOL-Phosphoramidit-Gruppierung gefunden werden. Dieses katalysiert die Addition von Diethylzink an Cyclohexenon mit ee-Werten von bis zu 67%, wobei sich der polymer gebundene Ligand seinem löslichen Analogon als ebenbürtig erwies.
TASO - Race Equality Gaps diff-in-diff - Leicester - Jan 2022
Creators: name: The Centre For Transforming Access And Student Outcomes In Higher Education (TASO)
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Race and Ethnicity
subject: Education
subject: Social and Behavioral Sciences
subject: Inequality and Stratification
subject: Sociology
subject: FOS: Sociology

description: This difference-in-differences design tests the impact of the University of Leicester's 'Decolonising the Curriculum toolkit' (curriculum reform) on closing the attainment gap between White and Black, Asian and Minority Ethnic (BAME) students.
Acetaminophen and mepirizole molecular adsorption studies on novel ζ – phosphorene nanotube based on first-principles investigation
Creators: name: Nagarajan, V.
name: Chandiramouli, R.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Based on the first-principles investigation, we explored the adsorption properties of two drug molecules on ζ – phosphorene nanotube (ζ-PNT) present in the aqueous environment. Firstly, the structural stableness of ζ-PNT is ensured with the support of formation energy (−5.005 eV/atom). Additionally, the electronic properties of ζ-PNT are studied by band structure and projected density of states (PDOS) spectrum. The energy band gap of ζ-PNT is found to be 1.298 eV, which confirms the semiconductor nature of the base substrate. The ζ-PNT is used as the base substrate to adsorb acetaminophen and mepirizole drug molecules in the contaminated water. The adsorption energy of ζ-PNT owing to molecular adsorption of drug molecules figures out to be in the chemisorption regime (−4.244 eV to −9.058 eV). Besides, the variation in the energy band, charge transfer, band structure, and electron density difference studies due to acetaminophen and mepirizole adsorption on ζ-PNT is reported. The outcome reveals that ζ-PNT is a possible material for acetaminophen and mepirizole removal from the contaminated water.
Refinement of the Equilibrium of Public Goods Games over Networks: Efficiency and Effort of Specialized Equilibria
Creators: name: Pandit, Parthe
name: Kulkarni, Ankur A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Optimization and Control (math.OC)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 91A43, 05C57, 91D30, 90C35

description: Recently Bramoulle and Kranton presented a model for the provision of public goods over a network and showed the existence of a class of Nash equilibria called specialized equilibria wherein some agents exert maximum effort while other agents free ride. We examine the efficiency, effort and cost of specialized equilibria in comparison to other equilibria. Our main results show that the welfare of a particular specialized equilibrium approaches the maximum welfare amongst all equilibria as the concavity of the benefit function tends to unity. For forest networks a similar result also holds as the concavity approaches zero. Moreover, without any such concavity conditions, there exists for any network a specialized equilibrium that requires the maximum weighted effort amongst all equilibria. When the network is a forest, a specialized equilibrium also incurs the minimum total cost amongst all equilibria. For well-covered forest networks we show that all welfare maximizing equilibria are specialized and all equilibria incur the same total cost. Thus we argue that specialized equilibria may be considered as a refinement of the equilibrium of the public goods game. We show several results on the structure and efficiency of equilibria that highlight the role of dependants in the network.
(200862) Henry Hooper
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Bedre modellering af trængsel i Landstrafikmodellen ved indarbejdelse af modul til beregning af krydsforsinkelser
Creators: name: Ravn, Peter
name: Espersen, Julie Storgaard
name: Frederiksen, Rasmus Dyhr
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2014

description: Denne artikel beskriver arbejdet med at udvikle og indsamle data til at opbygge en krydsdatabase til Landstrafikmodellen. Vejdirektoratet igangsatte i 2012, et projekt med henblik på at udvide LTM med krydsmodellering. Med indførsel af krydsmodellering vil landstrafikmodellen opnå en klar forbedring, idet trængsels- og flaskehals effekter kan modelleres mere detaljeret. Indarbejdelse af et krydsgenereringsmodul og indsamling af krydsdata til en krydsdatabase resulterer til gengæld et markant større datagrundlag og dermed større vedligeholdelsesomfang for modellen. I artiklen beskrives den teoretiske, tekniske og praktiske fremgangsmåde for indførelsen af kryds- modellering i Landstrafikmodellen. Som forventet påvirker beregninger med krydsforsinkelser i Landstrafikmodellen rutevalget og den samlede rejsetid samt lokale ændringer i rutevalget. Det videre arbejde består nu i at indarbejde krydsdata i Landstrafikmodellen, samt udvide den til at regner med 10 tidsperioder for bedre at kunne modellere trængslen. Arbejdet med krydsdatabasen har også givet ideer til at forbedre modelleringen af trængsel i kryds yderligere, ved bl.a. at indarbejde muligheden for delte spor og trafikstyrede kryds i modellen.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol 1 Nr 1 (2014): Proceedings from the Annual Transport Conference at Aalborg University
Design and Testing of Coils for Pulsed Electromagnetic Forming
Creators: name: Golovashchenko, S.
name: Bessonov, N.
name: Davies, R.
Publisher: name: Institut für Umformtechnik - Technische Universität Dortmund
Year: 2006
Subjects: subject: cooling
subject: electrical discharge
subject: sheet metal forming
subject: tool
subject: 620
subject: 670

description: Coil design influences the distribution of electromagnetic forces applied to both the blank and the coil. The required energy of the process is usually defined by deformation of the blank. However, the discharge also results in a significant amount of heat being generated and accumulating in the coil. Therefore, EMF process design involves working with three different problems: 1) propagation of an electromagnetic field through the coil-blank system and generation of pulsed electromagnetic pressure in specified areas, 2) high-rate deformation of the blank, and 3) heat accumulation and transfer through the coil with the cooling system. In the current work, propagation of an electromagnetic field in the coil, blank, die and surrounding air was defined using a consistent set of quasi stationary Maxwell equations applying a corresponding set of parameters for each media. Furthermore, a deformation of the blank driven by electromagnetic forces distributed through the volume of the blank was modeled using a solid mechanics equation of motion and the elastic plastic flow theory. During the discharge of capacitors the process was considered to be adiabatic due to the short duration of the pulse, so a heat transfer during the discharge time was neglected. The distribution of electric current density integrated during the discharge process defines the increase of temperature at every element of the coil. The distribution of temperature was calculated as a function of time using the energy conservation law.
title: Google Wave
title: Ein Zukunftsmarkt für Bibliotheken?
titleType: AlternativeTitle
Creators: name: Kahl, Andreas
Publisher: name: Technische Universität Dortmund
Year: 2010
Subjects: subject: Google Wave
subject: Innovation
subject: 000

description: Wird die Wissenschaft mit dem 'E-Mail 2.0' ganz neu funktionieren? Ist alles nur ein Hype? Ich werde in meinem Vortrag einige Funktionen und Einsatzmöglichkeiten von Google Wave für Bibliotheken zeigen. Schließlich werde ich einige Ideen anreissen, welche Dienstleistungen Bibliotheken mit der neuen Technologien anbieten könnten.
PATOGÊNESE E ACHADOS PATOLÓGICOS DA LEUCOSE ENZOÓTICA BOVINA: BREVE REVISÃO
Creators: name: Marcos Vinicius Vidal Silva
name: Gildson Matheus Lavosier Oliveira
name: Josilânia Laurentino da Silva
name: Laura Beatriz Sousa Oliveira
name: Kamila Ellen da Silva
name: Francisco Abner dos Santos Barbosa
name: Júlio César dos Reis Silva
name: Aline Bittencourt de Souza
Publisher: name: Zenodo
Year: 2025
Subjects: Linfossarcoma
Retrovírus
Imunossupressão

description: A Leucose Enzoótica Bovina (LEB) é uma enfermidade viral crônica, de ampla distribuição em rebanhos bovinos no Brasil e no mundo. Esta doença, causada pelo vírus da leucemia bovina (VLB), pertence à família Retroviridae e gênero Deltaretrovirus. A infecção pelo VLB é caracterizada pela proliferação anormal de linfócitos, podendo levar à formação de linfomas em vários órgãos e tecidos. A doença tem impacto significativo na saúde animal e na economia, devido à redução na produção leiteira, infertilidade e condenação de carcaças infectadas em frigoríficos. Apesar de não ser zoonótica, a LEB é de notificação obrigatória e requer medidas rigorosas de controle e prevenção.
Subdwarf B stars from the common envelope ejection channel
Creators: name: Xiong, H.
name: Chen, X.
name: Podsiadlowski, P.
name: Li, Y.
name: Han, Z.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: From the canonical binary scenario, the majority of sdBs are produced from low-mass stars with degenerate cores where helium is ignited in a way of flashes. Due to numerical difficulties, the models of produced sdBs are generally constructed from more massive stars with non-degenerate cores, leaving several uncertainties on the exact characteristics of sdB stars. Employing MESA, we systematically studied the characteristics of sdBs produced from the common envelope (CE) ejection channel, and found that the sdB stars produced from the CE ejection channel appear to form two distinct groups on the effective temperature-gravity diagram. One group (the flash-mixing model) almost has no H-rich envelope and crows at the hottest temperature end of the extremely horizontal branch (EHB), while the other group has significant H-rich envelope and spreads over the whole canonical EHB region. The key factor for the dichotomy of the sdB properties is the development of convection during the first helium flash, which is determined by the interior structure of the star after the CE ejection. For a given initial stellar mass and a given core mass at the onset of the CE, if the CE ejection stops early, the star has a relatively massive H-rich envelope, resulting in a canonical sdB generally. The fact of only a few short-orbital-period sdB binaries being in the flash-mixing sdB region and the lack of He-rich sdBs in short-orbital-period binaries indicate that the flash mixing is not very often in the products of the CE ejection. A falling back process after the CE ejection, similar to that happened in nova, is an appropriate way of increasing the envelope mass, then prevents the flash mixing.
description: accepted by A&A 12 pages, 11 figures
(200858) Samuel Edmund Falkiner
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Repurposing FDA-approved anti-diabetic drug to target H. pylori peptidyl deformylase using computer-based drug discovery approach
Creators: name: Singh, Atul Kumar
name: Maurya, Santosh
name: Kumar, Shashank
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Peptide deformylase (PDF), a metalloenzyme is an important and attractive target in antibacterial drug discovery. It removes the N-formyl group from the nascent peptide and generates a mature N-terminal end of the protein molecule. Acarbose is an FDA-approved microbial origin anti-diabetic drug and is known to alter the gut microbiota in clinical studies. The present study first time identifies the binding efficacy of acarbose isolated from a natural source against PDF. We performed molecular docking and molecular dynamics (MD) simulation studies to check the binding efficacy of acarbose with the catalytic site of Helicobacter pylori PDF. Molecular docking results of acarbose complexed with PDF showed a good docking score (−12.55 kcal/mole) in comparison to standard drug bind with PDF (−8.99 kcal/mole). Interaction with the amino acids (Gly95, Glu139, His138, Gly46 and Glu940) and metal ion present at the catalytic site of the test protein was found to be common in PDF during interaction with the acarbose and actinonin. Various parameters such as RMSD, RMSF, Rg, SASA, Hydrogen-bond formation, energy landscape and principal component analysis showed that the acarbose form stable and energetically stable complex with PDF in comparison to actinonin. Taken together, our study concludes that the acarbose possesses significant efficacy in binding at the catalytic site of H. pylori PDF. Acarbose is a FDA-approved anti-diabetic drug thus its antibacterial efficacy may be directly studied in clinical trials. Further, the in vitro and in vivo studies are needed to study the antibacterial mode of action of acarbose in physiological conditions.
Anvendelse af Landstrafikmodellen
Creators: name: Jelin, Adnan
name: Jensen, Henrik Nejst
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2014

description: Styrelserne i Transportministeriet har det seneste år anvendt Landstrafikmodellen til at beregne trafikale effekter af forskellige infrastrukturprojekter. I tæt samarbejde med DTU Transport er resultaterne blevet gransket og analyseret bl.a. gennem en brugergruppe knyttet til Landstrafikmodellen. Det har ført til en række forbedringer af modellen hvad angår brug af modellen, betydningen af forudsætninger, formatet af output fra modellen og kvaliteten af resultaterne (validering af modellen). Landstrafikmodellen er også kommet et skridt nærmere sin offentliggørelse og dermed en helt ny epoke mht. trafikberegninger af større infrastrukturprojekter. Ikke alene er der muligheder for at sammenligne projekter på tværs af landsdelene, der er også muligheder for en helt ny form for samarbejde mellem styrelserne og rådgiverne, som det har været tilfældet i analysen af Kattegatforbindelsen.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol 1 Nr 1 (2014): Proceedings from the Annual Transport Conference at Aalborg University
Investigating Proteins and Mechanisms Involved in Regulating E-C Coupling in Skeletal Muscle
Creators: name: Mollica, Janelle Paola
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfillment of the requirements for the degree of Doctor of Philosophy to the School of Life Sciences, College of Science, Health and Engineering, La Trobe University, Bundoora.
Language & Law and the Ordinary Meaning of "Child": How Corpus Linguistics Would Have Decided Ankrom v. Alabama
Creators: name: Roemling, Dana
Publisher: name: Zenodo
Year: 2021
Subjects: language and law
legal linguistics
statutory interpretation
ordinary meaning
corpus linguistics

description: Determining the meaning of a word in a statute remains debated in language and law. Corpus linguistics (CL) has seen a rise in interest in US statutory interpretation in the last decade, with the first legal decision involving CL being made in 2011 (Vogel et al. 2018). Thus, CL has shown to be a useful tool to provide insights into statutory interpretation. Within this tradition I analyse the criminal case of Ankrom v. Alabama, in which the defendant was found guilty of chemically endangering her child during pregnancy by taking controlled substances (2013). In sentencing the court construed that “child” also means “unborn child”. Following criticism of this decision (Angelotta & Appelbaum 2017) I consider what the ordinary meaning of “child” is and hence contribute to the research and literature on statutory interpretation using CL.

 I argue that the ordinary meaning of “child” can be established via relevant corpora (COCA, CANT, CAT), two of which were created for this analysis. First, I conduct an analysis of semantic patterns applying the methodology of Goldfarb (2017). This is a context-dependent approach to mapping meaning patterns (ibid.). Second, in a double dissociation analysis (Solan & Gales 2017) I show which other terms could have been expected in place of “child” and further disambiguate its usage. Additionally, I comment on the potential subjectivity introduced by the researcher in these kinds of analyses (Nyarko & Sanga 2020). Based on the results I argue that this is a valuable combination of approaches to solve meaning disputes in statutory interpretation.

 Case
 Ankrom v. Alabama, 152 So. 3d 397 (2013)

 References
 Angelotta, C., & Appelbaum, P. S. (2017). Criminal Charges for Child Harm from Substance Use in Pregnancy. The Journal of the American Academy of Psychiatry and the Law, 45(2), 193–203.
 Goldfarb, N. (2017). A Lawyer’s Introduction to Meaning in the Framework of Corpus Linguistics. BRIGHAM YOUNG UNIVERSITY LAW REVIEW, 2017(6), 1359–1416.
 Nyarko, J., & Sanga, S. (2020). A Statistical Test for Legal Interpretation: Theory and Applications. Available at http://dx.doi.org/10.2139/ssrn.3737292
 Solan, L. M., & Gales, T. (2017). Corpus Linguistics as a Tool in Legal Interpretation. Brigham Young University Law Review, 2017(6), 1311–1358.
 Vogel, F., Hamann, H., & Gauer, I. (2018). Computer-Assisted Legal Linguistics: Corpus Analysis as a New Tool for Legal Studies. Law & Social Inquiry, 43(04), 1340–1363.
Landstrafikmodellen
Creators: name: Brems, Camilla Riff
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2014

description: En fremskrivning af trafikken afhænger bl.a. af de opstillede forudsætninger. Landstrafikmodellens basisfremskrivning baseres for en række centrale forudsætninger på autoritative kilder som Finansministeriet, Danmarks Statistik og Energistyrelsen. I det følgende gennemgås hovedtrækkene i basisfremskrivningen for Landstrafikmodellen vers. 1.0.7, mens der fokuseres på de opstillede forudsætninger og deres betydning for basisfremskrivningen. Disse følsomhedsanalyser belyser i samme omgang et spænd for forventningerne til den fremtidige trafikvækst. De centrale forudsætninger omfatter: • Fremskrivning af BNP som specificeret af Finansministeriet i Konvergensprogrammet 2013 • Fremskrivning af befolkningen og dens lokalisering som specificeret af Danmarks Statistik i befolkningsfremskrivningen fra 2013 • Fremskrivning af arbejdspladserne opdelt på brancher som specificeret af Finansministeriet i Konvergensprogrammet 2013 • Fremskrivning af kørselsomkostninger i form af brændstofpriser og afgifter samt øget energieffektivitet som specificeret af Energistyrelsen i Forudsætninger for samfundsøkonomiske analyser 2012 • Infrastrukturforudsætninger i form af besluttede og finansierede projekter samt tilhørende køreplansforbedringer specificeret af Transportministeriet, Vejdirektoratet og Trafikstyrelsen For de fire første punkter er det aftalt, at forudsætningerne opdateres ca. hvert andet år, da det tilstræbes, at de forskellige beslutningsgrundlag baseres på ensartede forudsætninger, så de er sammenlignelige. Infrastrukturforudsætningerne opdateres i takt med de indgåede politiske aftaler.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol 1 Nr 1 (2014): Proceedings from the Annual Transport Conference at Aalborg University
Construction of all N=4 conformal supergravities
Creators: name: Butter, Daniel
name: Ciceri, Franz
name: de Wit, Bernard
name: Sahoo, Bindusar
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: All N=4 conformal supergravities in four space-time dimensions are constructed. These are the only N=4 supergravity theories whose actions are invariant under off-shell supersymmetry. They are encoded in terms of a holomorphic function that is homogeneous of zeroth degree in scalar fields that parametrize an SU(1,1)/U(1) coset space. When this function equals a constant the Lagrangian is invariant under continuous SU(1,1) transformations. The construction of these higher-derivative invariants also opens the door to various applications for non-conformal theories.
description: 5 pages, comments and references added, title changed, published version
GESTURES TOWARDS EMPTINESS: AN EXPLORATION OF RITUAL WITH REFERENCE TO BUDDHIST TRADITION AND INNOVATION
Creators: name: HOLTBERND, LUISE
Publisher: name: University of Plymouth
Year: 2007

description: Merged with duplicate record 10026.1/650 on 15.02.2017 by CS (TIS)
description: This thesis is a cross-relational enquiry into the nature of ritual as the subject of arts-based research. It can be described as ritual-led; or as an artist's manifestation of ritual. The core of the submission consists in an exhibition, comprising 30 pieces of framed, wall-hung artwork; 3 artist's books; some small-scale sculptural work and a documentary film. The research is concerned with parallel, related disciplines and modes of working: visual art, music, general ritual studies, pedagogy and the practice of Buddhist meditation and ritual. The following areas are being addressed: 1. The context of ritual in general, and Buddhist ritual in particular, both as traditional practice and in a contemporary setting. 2. Tradition and innovation as complementary forces in the evolution of ritual. 3. The interplay of pedagogy and art in the emergence of a body of work. 4. The effects of a personal life-crisis (contracting diabetes type 2) on the course of study; i.e. the discovery of ritualised artmaking as a form of healing and catalyst for increased artistic productivity. The foundation of the enquiry is both theoretical and practical. The experimental visual artwork employs a variety of techniques and media: ashes on paper; papermaking; wood pulp; and watercolour. The written thesis entails an analysis of process and outcome in each series of works, seen in relationship to Buddhist and educational disciplines. A four-year period of pedagogical developments in small and large-scale groups is documented, surveyed and evaluated. The conclusions are based on reflections of a holistic nature, integrating the different modalities of working and indicating the context of the studies within contemporary society.
Lernstrategien für das Arbeiten mit dynamischen Werkzeugen am Beispiel Dynamischer Geometriesysteme (DGS)
Creators: name: Haug, Reinhold
name: Leuders, Timo
Publisher: name: Gesellschaft für Didaktik der Mathematik
Year: 2012
Subjects: subject: 510

description: Das Lernen mit Computerunterstützung ist Gegenstand intensiver Forschungsbemühungen in der Mediendidaktik (als einen Zweig der pädagogischen Psychologie). Zugleich interessieren sich die Fachdidaktiken für das computergestützte Lernen aus ihrer jeweiligen fachspezifischen Perspektive. Forschungsstände und Theorierahmen sind hierbei vergleichsweise wenig vernetzt (eine der wenigen Ausnahmen im deutschsprachigen Raum ist Hischer, 2002). Der vorliegende Beitrag soll einige Brückenschläge zwischen Forschung zum Lernen mit computergestützten Lernumgebungen zwischen Mathematikdidaktik und Mediendidaktik andeuten. Diese Überlegungen explorieren die Situation ausgehend vom Bereich des Lernens mit Dynamischen Geometriesystemen.
Eulichas sikkimensis
Creators: name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Eulichadidae
Eulichas
Eulichas sikkimensis

description: Eulichas sikkimensis species complex
The species complex contains ten species distributed from Nepal and northern India, through continental south-eastern Asia, to Greater Sunda Islands and the Philippines. The highest diversity is reached in the Malay Peninsula. Species included in the complex are characterised by the reduction of the parameral subbasal hook.
description: Published as part of Hájek, Jiří, 2009, Revision of the genus Eulichas Jacobson, 1913 (Coleoptera: Eulichadidae) II. E. dudgeoni species group, pp. 1-44 in Zootaxa 2192 on page 24, DOI: 10.5281/zenodo.189396
Determinants of work-related musculoskeletal discomfort: A comparison between Malaysia and Australia
Creators: name: Maakip, Ismail
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Psychology and Public Health, College of Sciences, Health and Engineering, La Trobe University, Bundoora.

Thesis with publications.
The Clouds are breaking: tracing the Magellanic system with Gaia DR1 Mira variables
Creators: name: Deason, Alis J.
name: Belokurov, Vasily
name: Erkal, Denis
name: Koposov, Sergey E.
name: Mackey, Dougal
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We exploit the first data release from the Gaia mission to identify candidate Mira variables in the outskirts of the Magellanic Clouds. The repeated observations of sources during the initial phase of the Gaia mission is used to identify stars that show signs of variability. This variability information, combined with infrared photometry from 2MASS and WISE, allows us to select a clean sample of giants in the periphery of the LMC. We find evidence for Miras surrounding the LMC out to ~20 deg in all directions, apart from the North-West quadrant. Our sample does not generally follow the gas distribution of the Magellanic system; Miras are notably absent in the gaseous bridge between the LMC and SMC, but they are likely related to the stellar RR Lyrae bridge reported by Belokurov et al. (2016). The stellar stream discovered by Mackey et al. (2016) to the North of the LMC is almost perfectly delineated by our Mira variables, and likely extends further East toward the Galactic plane. The presence of an intermediate-age population in this stream advocates an LMC disc origin. We also find a significant excess of Miras to the East of the LMC; these more diffusely distributed stars are likely stripped SMC stars due to interactions with the LMC. Miras are also identified in regions of the sky away from the Clouds; we locate stars likely associated with known massive substructures, and also find potential associations with stripped SMC debris above the Galactic plane.
description: 12 pages, 12 figures. MNRAS accepted
Spannungsfelder der Mathematikdidaktik in der Lehrer(innen)bildung
Creators: name: Helmerich, Markus
Publisher: name: Gesellschaft für Didaktik der Mathematik
Year: 2012
Subjects: subject: 510

description: Ein Bildungsziel der Lehrer(innen)bildung an der Universität Siegen ist, Spannungsfelder von Lehr-/Lernprozessen aushalten zu können und reflektiert handlungsfähig zu werden. Diese Spannungsfelder wie z.B. "Form und Inhalt" oder "Produkt und Prozess" werden als fundamentale Ideen der Lehrer(innen)bildung vorgestellt. Die Spannungsfelder werden in der Konzeption von Lehrveranstaltungen wirksam, indem sie eine Orientierung geben, auf welchen Ebenen Kompetenzen aufgebaut werden können.
Improved quality with better user interface in transport models?
Creators: name: Malmin, Olav Kåre
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2014

description: This study discusses the challenge transport analysts face when using the Norwegian Regional Transport Model (RTM) and it’s user interface. The aim of this study is to iden????fy typical challenges the users face when using a transport model like RTM, and discuss possible changes in future development of the transport model for be????er usability. A review of the user support issues from 2013 to 2014 (N=62) shows that 63 % of all requests were related to the methods and procedures in the model and uncertainty on how to approach those methods in a analysis. 26 % of the requests were caused by direct and systema????c errors in the input data. The conclusion of the study is that the models user interface should be developed to help the user be????er understand the methodology of the transport model.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol 1 Nr 1 (2014): Proceedings from the Annual Transport Conference at Aalborg University
Beiträge des HDZ zur Qualitätsentwicklung an der Universität Dortmund
Creators: name: Schneider, Ralf
Publisher: name: Hochschuldidaktisches Zentrum der Technischen Universität Dortmund
Year: 2005
Subjects: subject: 370

description: Journal Hochschuldidaktik ; 16. Jahrgang 2005 Heft 2
Bump-hunting in LHC ttbar events
Creators: name: Czakon, Michal
name: Heymes, David
name: Mitov, Alexander
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We demonstrate that a purposefully normalised NNLO top pair invariant mass differential spectrum can have very small theoretical uncertainty and, in particular, a small sensitivity to the top quark mass. Such observable can thus be a very effective bump-hunting tool for resonances decaying to top pair events during LHC Run II and beyond. To illustrate how the approach works, we concentrate on one specific example of current interest, namely, the possible 750 GeV di-gamma excess resonance Phi. Considering only theoretical uncertainties, we demonstrate that it is possible to distinguish pp -> Phi -> tt signals studied in the recent literature [Hespel, Maltoni and Vryonidou, arXiv:1606.04149] from the pure SM background with very high significance. Alternatively, in case of non-observation, a strong upper limit on the decay rate Phi -> tt can be placed.
description: 8 pages, 6 figures, analytic fits attached, plot on top-mass sensitivity for the invariant mass distribution added, appendix on top-mass sensitivity of differential distributions added, minor additional changes and comments, matches published version