cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Isomerization reactions of enesulfonamides and enecarbamates using platinum(II) and silver(I) catalysts
Creators: name: Dodd, Jennifer Megan
Publisher: name: University of British Columbia
Year: 2011

description: The scope of a platinum(II) chloride catalyzed isomerization of enesulfonamides and enecarbamates that proceeds by alkyne activation followed by Friedel-Crafts reaction was investigated. Seven enesulfonamide and enecarbamate derivatives with a variety of aromatics and heteroaromatics were synthesized. Exposure to catalytic platinum chloride generated tetracyclic products in 17 to 78% yield. The regioselectivity of the attack on the alkyne in this reaction varied from 8:1 to 1:0 mixtures of products. Additionally, a silver-catalyzed ring expansion reaction of enesulfonamides containing 2-alkynyl indoles to generate eight-membered rings was investigated. A series of control reactions were performed to determine the mechanism, which was found to proceed by interaction of the catalyst with the indole ring. Thirteen enesulfonamide derivatives containing aromatic, heteroaromatic and carbonyl substituents were submitted to silver and acid catalysis, yielding azocine derivatives in 0 to 97% yield.
Polymer Field-Theory Simulations on Graphics Processing Units
Creators: name: Delaney, Kris T.
name: Fredrickson, Glenn H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We report the first CUDA graphics-processing-unit (GPU) implementation of the polymer field-theoretic simulation framework for determining fully fluctuating expectation values of equilibrium properties for periodic and select aperiodic polymer systems. Our implementation is suitable both for self-consistent field theory (mean-field) solutions of the field equations, and for fully fluctuating simulations using the complex Langevin approach. Running on NVIDIA Tesla T20 series GPUs, we find double-precision speedups of up to 30x compared to single-core serial calculations on a recent reference CPU, while single-precision calculations proceed up to 60x faster than those on the single CPU core. Due to intensive communications overhead, an MPI implementation running on 64 CPU cores remains two times slower than a single GPU.
description: (12 pages, 7 figures)
title: HTA und komplexe Herausforderungen: national, international und  adaptiv?
Creators: name: Rüther, Alric
name: Herrmann, Kirsten H
name: Jensen, Katrin
name: Siebert, Uwe
name: Schramm, Wendelin
name: Schwarzer, Ruth
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Pharmacoepidemiology
subject: Standards and guidelines
subject: Policy
subject: 610 Medical sciences; Medicine

description: Der interdisziplinäre Workshop der AGs / AKs HTA, Methodik Systematischer Reviews, Gesundheitsökonomie und Medical Decision Making möchte auch in diesem Jahr einen Überblick zu den letzten Entwicklungen und aktuellen Herausforderungen im jeweiligen Bereich geben und ausgewählte[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
ПНЕВМОЦИСТНАЯ И ЦИТОМЕГАЛОВИРУСНАЯ ПНЕВМОНИЯ КАК ПРОЯВЛЕНИЕ СИНДРОМА ВОССТАНОВЛЕНИЯ ИММУННОЙ СИСТЕМЫ
Creators: name: ДЕГТЯРЕВА С.Ю.
name: ЗИМИНА В.Н.
name: БЕЛОБОРОДОВА Е.Н.
name: РОЖДЕСТВЕНСКАЯ К.В.
name: ПЕРЕГУДОВА А.Б.
name: КАМИНСКИЙ Г.Д.
Publisher: name: Трудный пациент
Year: 2019
Subjects: ВИЧ-ИНФЕКЦИЯ
ИММУНОДЕФИЦИТ
ПНЕВМОЦИСТНАЯ ПНЕВМОНИЯ
ЦИТОМЕГАЛОВИРУСНАЯ ИНФЕКЦИЯ
СИНДРОМ ВОССТАНОВЛЕНИЯ ИММУННОЙ СИСТЕМЫ (СВИС)
КЛИНИЧЕСКИЙ СЛУЧАЙ
HIV
IMMUNODEFICIENCY
PNEUMOCYSTIS PNEUMONIA
CYTOMEGALOVIRUS INFECTION
IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS)
CLINICAL CASE

description: Представлен пример клинического наблюдения пациента с ВИЧ-инфекцией с выраженным иммунодефицитом, у которого развилась пневмоцистная пневмония (ПЦП) и манифестная цитомегаловирусная инфекция (ЦМВи) с поражением легких как проявление синдрома восстановления иммунной системы (СВИС) на фоне начала эффективной антиретровирусной терапии. На фоне проводимой этиотропной терапии трудности дифференциальной диагностики состояли в ухудшении состояния, которое было связано как с манифестацией СВИС, так и с неадекватной дозировкой препаратов, из-за выраженных побочных эффектов терапии; а также в относительно редком проявлении СВИС в виде полиинфекционного поражения ПЦП и манифестной ЦМВи. Однако своевременно проведенное обследование позволило установить этиологическую причину СВИС и назначить адекватную терапию. На фоне лечения у пациента возникали нежелательные явления 3-4 степени тяжести, однако при пристальном врачебном контроле оказалась возможной коррекция этих нежелательных явлений без отмены препаратов, что позволило в конечном счете добиться излечения пациента.
Constraining Radio Emission from Magnetars
Creators: name: Lazarus, Patrick
name: Kaspi, Victoria M.
name: Champion, David J.
name: Hessels, Jason W. T.
name: Dib, Rim
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report on radio observations of five magnetars and two magnetar candidates carried out at 1950 MHz with the Green Bank Telescope in 2006-2007. The data from these observations were searched for periodic emission and bright single pulses. Also, monitoring observations of magnetar 4U0142+61 following its 2006 X-ray bursts were obtained. No radio emission was detected was detected for any of our targets. The non-detections allow us to place luminosity upper limits (at 1950 MHz) of approximately L < 1.60 mJy kpc^2 for periodic emission and L < 7.6 Jy kpc^2 for single pulse emission. These are the most stringent limits yet for the magnetars observed. The resulting luminosity upper limits together with previous results are discussed, as is the importance of further radio observations of radio-loud and radio-quiet magnetars.
description: 11 pages, 4 figures
Validation of Lyric Focus Questionnaire with a Lyric Comprehension Task
Creators: name: Cannistraro, Julia
name: Vuvan, Dominique T.
Publisher: name: OSF Registries
Year: 2022
Subjects: subject: Arts and Humanities
subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Validation of the Lyric Focus Questionnaire (LFQ), a self-report questionnaire that quantifies individual differences in lyric focus during song listening
Testing the Kerr-nature of stellar-mass black hole candidates by combining the continuum-fitting method and the power estimate of transient ballistic jets
Creators: name: Bambi, Cosimo
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Astrophysical black hole candidates are thought to be the Kerr black holes predicted by General Relativity, as these objects cannot be explained otherwise without introducing new physics. However, there is no observational evidence that the space-time around them is really described by the Kerr solution. The Kerr black hole hypothesis can be tested with the already available X-ray data by extending the continuum-fitting method, a technique currently used by astronomers to estimate the spins of stellar-mass black hole candidates. In general, we cannot put a constraint on possible deviations from the Kerr geometry, but only on some combination between these deviations and the spin. The measurement of the radio power of transient jets in black hole binaries can potentially break this degeneracy, thus allowing for testing the Kerr-nature of these objects.
description: 8 pages, 6 figures. v2: some typos corrected
title: Adaptive Pathways
Creators: name: Schwarzer, Ruth
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Pharmacoepidemiology
subject: Standards and guidelines
subject: Policy
subject: 610 Medical sciences; Medicine

description: Hintergrund: Der medizinische Direktor der EMA, Hans-Georg Eichler, hat 2010 begonnen, ein adaptive licensing Konzept für Arzneimittel auszuarbeiten, es weltweit verbreitet, international verschiedenste Kooperationen und Initiativen gestartet. Später adaptive pathways genannt, tritt an die[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
Genomic Studies of Gene Expression Errors and Their Evolutionary Ramifications
Creators: name: Sun, Mengyi
Publisher: name: My University
Year: 2021
Subjects: subject: Molecular error
subject: Gene expression noise
subject: Gene order
subject: Codon usage
subject: Translation accuracy
subject: Ecology and Evolutionary Biology
subject: Science

description: Gene expression produces biologically functional RNAs and proteins and is essential for life. Nevertheless, gene expression is subject to several types of errors that are generally harmful. Despite the prevalence and significant consequences of expression errors, their genome-wide patterns are not well characterized. Furthermore, the evolutionary ramifications of such errors are poorly understood. In my dissertation, I address the above questions using novel computational approaches. I focus on two types of gene expression errors: (i) stochastic gene expression, which leads to a variation of the expression level among isogenic cells in the same environment (gene expression noise), and (ii) mistranslation, which induces protein misfolding and can be toxic to the cells. My thesis has three main chapters in addition to the introduction and conclusion chapters. First, in Chapter 2, I studied gene expression noises of individual genes. I decomposed noises of 3975 mouse genes into intrinsic noise and extrinsic noises and studied their biological mechanisms and evolution consequences. Next, in Chapter 3, I move forward to consider gene expression noises for pairs of genes simultaneously. I discovered chromosome-wide co-fluctuation in expression for linked genes, which is partly due to chromatin co-accessibilities of linked loci attributable to three-dimensional proximity. I further found that genes encoding components of the same protein complex are more likely to become linked during evolution due to natural selection for intracellular among-component dosage balance. Thus, selection for mitigating the harm of expression noise drives the nonrandom genomic distributions of genes. Finally, in Chapter 4, I studied yet another kind of expression error: mistranslation. I focused on the relationship between mistranslation and codon usage. Specifically, I provide the first direct and global evidence for a prominent but unresolved hypothesis: preferred codons are translated more accurately. Furthermore, I showed that this proposition is generally true across three domains of life. Interestingly, the relative translational accuracies of synonymous codons vary drastically among species, which is mainly explained by the variation of tRNA compositions. Together with other information, these findings suggest that codon usage coevolves with the cellular tRNA pool to maximize translational accuracy and efficiency. In conclusion, my dissertation documents the genome-wide patterns of gene expression errors and demonstrates their profound impacts on both molecular and phenotypic evolution. The knowledge gained has implications beyond expression errors because of the universality of molecular errors in cellular life.
Spitzer Observations of MF 16 Nebula and the associated Ultraluminous X-ray Source
Creators: name: Berghea, Ciprian T.
name: Dudik, Rachel P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present Spitzer Infrared Spectrograph (IRS) observations of the ultra-luminous X-ray source (ULX) NGC 6946 X-1 and its associated nebula MF 16. This ULX has very similar properties to the famous Holmberg II ULX, the first ULX to show a prominent infrared [O IV] emission line comparable to those found in AGN. This paper attempts to constrain the ULX Spectral Energy Distribution (SED) given the optical/UV photometric fluxes and high-resolution X-ray observations. Specifically, Chandra X-ray data and published Hubble optical/UV data are extrapolated to produce a model for the full optical to X-ray SED. The photoionization modeling of the IR lines and ratios is then used to test different accretion spectral models. While either an irradiated disk model or an O-supergiant plus accretion disk model fit the data very well, we prefer the latter because it fits the nebular parameters slightly better. In this second case the accretion disk alone dominates the extreme-UV and X-ray emission, while an O-supergiant is responsible for most of the far-UV emission.
description: 26 pages, 7 figures, accepted by ApJ
РЕДКИЕ СИСТЕМНЫЕ ВАСКУЛИТЫ В КЛИНИЧЕСКОЙ ПРАКТИКЕ: ТРУДНОСТИ ДИАГНОСТИКИ
Creators: name: ГУРИЖЕВА М.В.
name: НАХУШЕВА А.Р.
name: МУСХАНОВ Э.А.
name: КУЧМЕЗОВА Ф.А.
name: ШАБАТУКОВА М.Я.
name: САРАКАЕВА ДЖ.И.
name: ШОГЕНОВ Х.К.
Publisher: name: Трудный пациент
Year: 2019
Subjects: СИСТЕМНЫЕ ВАСКУЛИТЫ
ГРАНУЛЕМАТОЗ ВЕГЕНЕРА
ANCA-АССОЦИИРОВАННЫЙ ВАСКУЛИТ
SYSTEMIC VASCULITIS
GRANULOMATOSIS WITH POLYANGIITIS
WEGENER'S GRANULOMATOSIS
ANCA-ASSOCIATED VASCULITIS

description: Гранулематоз Вегенера это мультисистемный, аутоиммунный, некротизирующий васкулит, неизвестной этиологии, поражающий сосуды мелкого калибра. Заболевание считается редким, однако распространенность патологии в европейских странах за последние 30 лет возросла в 4 раза. В России крупные эпидемиологические исследования не проводились. Утвержденной классификации нет.
УРАТСНИЖАЮЩАЯ ТЕРАПИЯ У БОЛЬНЫХ ДИАБЕТИЧЕСКОЙ НЕФРОПАТИЕЙ
Creators: name: ПОПОВ С.В.
name: СТУРОВ Н.В.
name: ФРЕЙРЕ ДА СИЛЬВА Т.
name: БЕРИША А.
name: КОТИДИС И.
Publisher: name: Трудный пациент
Year: 2019
Subjects: САХАРНЫЙ ДИАБЕТ
ДИАБЕТИЧЕСКАЯ НЕФРОПАТИЯ
ГИПЕРУРИКЕМИЯ
УРАТСНИЖАЮЩАЯ ТЕРАПИЯ
ФЕБУКСОСТАТ
DIABETES MELLITUS
DIABETIC NEPHROPATHY
HYPERURICEMIA
URATE-LOWERING THERAPY
FEBUXOSTAT

description: Повышение уровня мочевой кислоты в сыворотке крови широко распространено у пациентов с хронической болезнью почек и является независимым предиктором развития сахарного диабета 2 типа и сердечно-сосудистых осложнений. В статье представлены результаты некоторых исследований взаимосвязи уровня сывороточной мочевой кислоты с риском прогрессирования диабетической нефропатии. Согласно результатам одного из исследований, умеренная гиперурикемия оказалась ассоциированой с развитием хронической болезни почек у больных сахарным диабетом 2 типа, а повышенный уровень мочевой кислоты в сыворотке крови обуславливал примерно двукратное увеличение риска диабетической нефропатии. В последнее время для улучшения почечной функции обсуждается возможность применения уратснижающих препаратов у пациентов с диабетической нефропатией и гиперурикемией. В статье продемонстрированы результаты исследования эффективности ингибитора ксантиноксидазы фебуксостата у данной категории пациентов. По результатам проведенного исследования, была установлена возможность замедления прогрессирования хронической болезни почек за счет снижения уровня мочевой кислоты при терапии этим препаратом пациентов с сахарным диабетом.
Solutions to sign problems in lattice Yukawa models
Creators: name: Chandrasekharan, Shailesh
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We prove that sign problems in the traditional approach to some lattice Yukawa models can be completely solved when the fermions are formulated using fermion bags and the bosons are formulated in the worldline representation. We prove this within the context of two examples of three dimensional models, symmetric under $U_L(1) \times U_R(1) \times Z_2 ({Parity})$ transformations, one involving staggered fermions and the other involving Wilson fermions. We argue that these models have interesting quantum phase transitions that can now be studied using Monte Carlo methods.
description: 5 pages, 1 figure (Fixed minor typographical errors, expanded the discussion to include solution to the sign problem with the conventional bosonic action and added a reference.)
Estratégias linguístico-discursivas de tratamento humorístico da morte em comerciais televisivos
Creators: name: Palácios, Annamaria Da Rocha Jatobá
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: Este texto procura identificar e compreender, do ponto de vista semântico, abordagens humorísticas desenvolvidas pela narrativa publicitária quando anuncia produtos e serviços e os relaciona ao universo simbólico da morte. O tratamento cômico empregado pela publicidade quase sempre pauta-se pela incorporação do inesperado, da surpresa, das associações e metáforas livremente empregadas. Portanto, mesmo ao enfrentar o conhecido medo ocidental diante da morte, a publicidade a aciona, enunciativamente, por meio de estratégias linguístico-discursivas que dela zombam, caçoam, tripudiam e fazem graça. A prática publicitária enfrenta o permanente desafio de estabelecer distinções entre incontáveis produtos funcionalmente semelhantes, a fim de conquistar potenciais consumidores, constituídos por públicos cada vez mais diversos e segmentados. O atual interesse dos homens do marketing em incorporar produtos e serviços associados ao universo simbólico da morte pode ser explicado pelo fato de que ela (a morte) é a inexorável certeza que atinge a todos nós. A análise é alicerçada em pressupostos das teorias semânticas, em particular das teorias da argumentação (Ducrot) e dos postulados teóricos desenvolvidos por Grice, nos domínios das reflexões identificadas como da pragmalinguística. Pontuais contributos sociológicos, antropológicos e filosóficos auxiliam na compreensão de parte do legado histórico sobre a morte, na cultura ocidental. As estratégias linguístico-discursivas empregadas pela publicidade, quando aciona produtos e serviços direta ou indiretamente relacionados com o universo semântico da morte, são observadas em alguns comerciais televisivos selecionados para tal fim.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
Perspectives of the Business sector on social enterprise
Creators: name: Lai, Daniel
Publisher: name: Trico Charitable Foundation
Year: 2012

description: Trico Charitable Foundation commissioned Dr. Daniel Lai, of the University of Calgary, to perform a study examining the perceptions of the business sector towards social entrepreneurship in terms of perceived competiveness, value, social mission and social impacts in British Columbia and Alberta. The research is entitled, “Perspectives of the Business Sector on Social Enterprise”.
title: Routinedaten für Systematic Reviews zu Behandlungseffekten
Creators: name: Hemkens, Lars G.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Pharmacoepidemiology
subject: Standards and guidelines
subject: Policy
subject: 610 Medical sciences; Medicine

description: Einführung: Die Menge routinemässig gesammelter Gesundheitsdaten erreicht gigantische Ausmasse. Massive Anstrengungen werden unternommen, diese Daten zur Bewertung von Effekten medizinischer Behandlungen zu nutzen. Das stellt Autoren systematischer Reviews vor zahlreiche Herausforderungen,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
РАК ПОЛОВОГО ЧЛЕНА: СОВРЕМЕННЫЕ ПОЗИЦИИ ОРГАНОСОХРАНЯЮЩЕГО ЛУЧЕВОГО ЛЕЧЕНИЯ
Creators: name: ПАНЬШИН Г.А.
name: ТИТОВА В.А.
name: ПЕТРОВСКИЙ В.Ю.
Publisher: name: Трудный пациент
Year: 2019
Subjects: РАК ПОЛОВОГО ЧЛЕНА
ДИСТАНЦИОННАЯ ЛУЧЕВАЯ ТЕРАПИЯ
БРАХИТЕРАПИЯ
ИСТОЧНИКИ 60СО И 192IR
PENILE CANCER
EXTERNAL BEAM RADIATION THERAPY
BRACHYTHERAPY
60CO AND 192IR SOURCES

description: В статье представлены варианты консервативного лечения рака полового члена в виде сочетания дистанционной лучевой терапии и брахитерапии низкомощностными источниками 60Со и высокомощностными 192Ir, а также самостоятельной конформной дистанционной лучевой терапии с локальным повышением доз на область первичной опухоли.
Magnetic Instability on the Surface of Topological Insulators
Creators: name: Baum, Yuval
name: Stern, Ady
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Gapless surface states that are protected by time reversal symmetry and charge conservation are among the manifestations of 3D topological insulators. In this work we study how electron-electron interaction may lead to spontaneous breaking of time reversal symmetry on surfaces of such insulators. We find that a critical interaction strength exists, above which the surface is unstable to spontaneous formation of magnetization, and study the dependence of this critical interaction strength on temperature and chemical potential.
description: 4 pages, 3 figures
title: Aktive Zusammenführung von medizinischen Basisdaten für Versorgungsmanagement und Forschung
Creators: name: Schepers, Josef
name: Pigeot, Iris
name: Ahrens, Wolfgang
name: Hummel, Michael
name: Ihle, Peter
name: Mansmann, Ulrich
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Intersectoral health care
subject: Quality and performance indicators of health care
subject: 610 Medical sciences; Medicine

description: Im deutschen Gesundheitssystem existieren einige Datensammlungen bei Leistungserbringern, Leistungsträgern (GKV; PKV; GUV; GRV; GPV; kommunal), Behörden, Selbstverwaltungs- und Forschungseinrichtungen, die über ihre Versorgungs- und Administrationszwecke hinaus für Forschung und [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
As Campanhas de Publicidade exterior e a sua memorização - Estudo realizado junto de um grupo de consumidores
Creators: name: Lopes, Paula
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: As campanhas de publicidade são efectuadas pelos anunciantes e pelas marcas com o objectivo de comunicar aos seus públicos informação sobre os seus produtos e / ou serviços. Mas para além disso existem um conjunto de factores que são inerentes à comunicação publicitária como a memorização das suas campanhas pelos consumidores devido a vários factores: tipo de produto, criatividade da campanha e mensagem comunicada. Associado à Publicidade Exterior em particular existem outros factores como o conjunto da imagem e do lettering colocados no suporte de Outdoor. A concepção gráfica dos posters e Outdoors faz a diferença na captação da atenção do consumidor, o que justifica a investigação que tem sido desenvolvida sobre a medição da eficácia da criatividade da campanha. O objecto de estudo deste trabalho de investigação é perceber se os consumidores memorizam as marcas que incluem a publicidade exterior no seu plano de meios. A metodologia aplicada a esta pesquisa consiste numa revisão bibliográfica sobre a temática e num questionário aplicado a um grupo de consumidores para saber se memorizaram as marcas que anunciam em Publicidade Exterior em Portugal.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
title: Research in Progress – Ein Workshop der DGEpi-Initiative „besser forschen“
Creators: name: Buttmann-Schweiger, Nina
name: Grube, Maike
name: Völzke, Henry
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Statistical methods in epidemiology
subject: Knowledge representation and processing
subject: 610 Medical sciences; Medicine

description: Hintergrund: In der gesundheitswissenschaftlichen Community fehlen Möglichkeiten, sich themenbezogen und über die Hochschulen und Forschungsverbünde hinweg über aktuell in Arbeit befindliche Forschungsprojekte auszutauschen und diese gemeinsam weiterzuentwickeln. Die Veröffentlichung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ МЕТАСТАТИЧЕСКИХ ОПУХОЛЕЙ НАДПОЧЕЧНИКОВ
Creators: name: МУРАДЯН А.Г.
name: КОСТИН А.А.
name: ТОЛКАЧЕВ А.О.
name: ВОРОБЬЕВ Н.В.
name: КУЛЬЧЕНКО Н.Г.
Publisher: name: Трудный пациент
Year: 2019
Subjects: METASTATIC ADRENAL TUMORS
SECONDARY ADRENAL TUMORS
SURGICAL TREATMENT OF ADRENAL TUMORS
LAPAROSCOPIC ADRENALECTOMY
ROBOTIC ADRENALECTOMY

description: Бессимптомные метастатические опухоли надпочечников встречаются в 5-7%. Вторичные опухоли надпочечников (при наличии в анамнезе злокачественной патологии) выявляются в 32-73% случаев. В случае подтверждения вторичного опухолевого поражения надпочечника, кроме лекарственной терапии, возможными вариантами лечения являются локальные методы воздействия, такие как хирургическое лечение, аблационные методики и стереотаксическая лучевая терапия. В данном обзоре литературы освещаются вопросы хирургического лечения метастатических опухолей надпочечников. По данным нескольких исследований, пациенты имеют преимущество в выживаемости при хирургическом лечении солитарных опухолей, в зависимости от локализации первичной опухоли. Лапароскопическая адреналэктомия рассматривается большинством авторов как «золотой стандарт» лечения пациентов с метастатическими опухолями надпочечников. Роботассистированная адреналэктомия может быть альтернативой лапароскопическим операциям при вторичных опухолях надпочечников.
Evolution and Control of Oxygen Order in a Cuprate Superconductor
Creators: name: Poccia, Nicola
name: Fratini, Michela
name: Ricci, Alessandro
name: Campi, Gaetano
name: Barba, Luisa
name: Vittorini-Orgeas, Alessandra
name: Bianconi, Ginestra
name: Aeppli, Gabriel
name: Bianconi, Antonio
Publisher: name: arXiv
Year: 2011
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The disposition of defects in metal oxides is a key attribute exploited for applications from fuel cells and catalysts to superconducting devices and memristors. The most typical defects are mobile excess oxygens and oxygen vacancies, and can be manipulated by a variety of thermal protocols as well as optical and dc electric fields. Here we report the X-ray writing of high-qualitysuperconducting regions, derived from defect ordering, in the superoxygenated layered cuprate, La2CuO4+y. Irradiation of a poor superconductor prepared by rapid thermal quenching results first in growth of ordered regions, with an enhancement of superconductivity becoming visible only after a waiting time, as is characteristic of other systems such as ferroelectrics, where strain must be accommodated for order to become extended. However, in La2CuO4+y, we are able to resolve all aspects of the growth of (oxygen) intercalant order, including an extraordinary excursion from low to high and back to low anisotropy of the ordered regions. We can also clearly associate the onset of high quality superconductivity with defect ordering in two dimensions. Additional experiments with small beams demonstrate a photoresist-free, single-step strategy for writing functional materials.
description: 12 pages, 3 figures
Representações televisivas do espaço privado urbano nos anúncios de brinquedos para crianças
Creators: name: Magalhães, Luísa
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: Sem resumo disponível.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
Beamforming of temporally broadband bandpass plane waves using 2D FIR trapezoidal filters
Creators: name: Gunaratne, Thushara Kanachana
Publisher: name: Science
Year: 2006

description: Bibliography: p. 151-156
description: Two new discrete-domain methods are proposed for the beamforming of two-dimens­ional temporally broadband bandpass plane waves using two-dimensional spatio-temporal finite impulse response filters with novel trapezoidal-shaped passbands. The first method employs a complex-coefficient two-dimensional finite impulse re­sponse filter structure having an asymmetric trapezoidal-shaped passband at base­band and achieves the minimum possible temporal sampling rate for a given tem­poral bandwidth. The second method employs a real-coefficient polyphase two-dimensional finite impulse response filter structure having a rectangularly-symmetric double-trapezoidal-shaped passband and requires 50% less computational complexity for the same temporal bandwidth. Experimental results have confirmed that both methods are equally capable of enhancing the desired two-dimensional temporally broadband bandpass plane waves according to their directions of arrival under severe co-channel interference and multipath fading.
Ring galaxies from off-centre collisions
Creators: name: Mapelli, M.
name: Mayer, L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the formation of RE galaxies (i.e. of collisional ring galaxies with an empty ring), with N-body/SPH simulations. The simulations employ a recipe for star formation (SF) and feedback that has been shown to be crucial to produce realistic galaxies in a cosmological context. We show that RE galaxies can form via off-centre collisions (i.e. with a non-zero impact parameter), even for small inclination angles. The ring can be either a complete ring or an arc, depending on the initial conditions (especially on the impact parameter). In our simulations, the nucleus of the target galaxy is displaced from the dynamical centre of the galaxy and is buried within the ring, as a consequence of the off-centre collision. We find that the nucleus is not vertically displaced from the plane of the ring. We study the kinematics of the ring, finding agreement with the predictions by the analytic theory. The SF history of the simulated galaxies indicates that the interaction enhances the SF rate. We compare the results of our simulations with the observations of Arp 147, that is the prototype of RE galaxies.
description: 10 pages, 11 figures, MNRAS, in press
Trilha do Filme Publicitário
Creators: name: José, Carmen Lucia
name: Bigal, Solange Maria
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: Nós últimos 15 anos, a trilha sonora passou a ocupa um lugar de destaque nas linguagens audiovisuais. As novas tecnologias e, consequentemente, os novos diálogos metalinguísticos entre imagem e som criaram, de um lado, outros usos para a fragmentação das canções, tornadas trilha; de outro, passaram a destacar o novo desenho cultural do público consumidor médio brasileiro que, além de ser o foco potencial das Marcas, é também consumidor de informação, isto é, usuário de linguagens. Nossa expectativa é compreender o uso da canção, especificamente, como trilha sonora do filme publicitário: como a canção tornada trilha é reutilizada na associação com a Marca e o que a seleção de canções aponta quanto ao público-alvo em se tratando de repertório cultural. No emprego da canção como trilha, a importância que o áudio vem conquistando é produto, principalmente, da autonomia e da proeminência informacional que a trilha tem adquirido em relação à visualidade em movimento. No Brasil, com a política de promoção econômica de pessoas da classe C / D para a posição de consumidor médio, é possível verificar tanto a presença de outros gêneros musicais mais populares e/ ou periféricos no rol da canção para compor a programação musical das emissoras de rádio e o Cds das canções que compõem as trilhas das telenovelas.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
First-principles studies of transition metal doped systems and hyperﬁne coupling constants of muoniated butyl radicals
Creators: name: Chen, Yakun
Publisher: name: University of British Columbia
Year: 2010

description: The ﬁrst part of the thesis examines, using density functional theory (DFT) calculations, the effects of introducing transition metals (TMs) into different systems, including small Au clusters; carbon nanotubes (CNTs); pristine and defected boron nitride nanotubes (BNNTs). The results show that the frontier molecular orbitals of the TM modiﬁed systems are usually localized around the doping site and the reactivities of these systems are often improved. In the case of small TM clusters, both PtAum and Aun tend to be planar in their ground state. N₂ and O₂ adsorption onto these clusters results in different adsorption conﬁgurations due to different orbital interactions. With regard to the TM modiﬁed CNTs, the endo-TM-doped CNTs are less stable than the corresponding exo-doped isomers due to the large geometric strain caused by deformation. The exo-doped SWCNTs are better electron donors than their endo-doped counterparts. As for the Pt modiﬁed BNNTs, binding energy analysis revealed that a Pt atom can move freely on a pristine BNNT. But the Pt atom is trapped between the B B bond at the defect site if a Stone-Wales defect exists. In both cases, the hosting BNNTs are wide-gap semiconductors with slightly improved reactivities. In comparison, BNNTs doped with Pt atoms are narrow-gap semiconductors with greatly enhanced reactivities. Both MP2 EPR-III and B3LYP EPR-III calculations were used to optimize butyl isomers and calculate hyperﬁne coupling constants (HFCCs) to explain experimental data. The C-Mu distance was elongated to 1.076 times the corresponding equilibrium C-H bond length to mimic vibrationally average β-muoniated radical geometries so as to calculate the muon HFCCs. Some muon HFCCs and most proton HFCCs were satisfactorily reproduced by the B3LYP calculations due to error cancellations, whereas other cases were better predicted by the MP2 calculations. The torsional potential energy surface (PES) of the sec-butyl radical was also studied. The cis conformation, which was observed in experiments, was unobtainable using some common DFT functionals, but can be identiﬁed by calculations using wavefunction theory or some modiﬁed hybrid functionals. Changes in basis set only modify the shape of the PES slightly.
title: Regionale fachärztliche Versorgung und demographischer Wandel in Deutschland – Szenarien zur dermatologischen Versorgung für das Jahr 2035
Creators: name: Kis, Anne
name: Augustin, Matthias
name: Augustin, Jobst
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Populations in transition
subject: Health geography
subject: Demographic change
subject: Statistical methods for health services research
subject: Standards and guidelines
subject: Data mapping
subject: 610 Medical sciences; Medicine

description: Hintergrund: Der demographische Wandel führt sowohl auf Patienten- als auch auf Ärzteseite zu regionalen Veränderungen. Insbesondere strukturschwache Regionen müssen aufgrund der Altersstruktur der dort praktizierenden Ärzt/innen sowie gleichzeitig auftretende Wiederbesetzungschwierigkeiten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
More than Clearing the Clutter: The Imperative Role of Efferocytosis in Repair and Immune Reprogramming in the Damaged Nervous System
Creators: name: Huffman, Lucas
Publisher: name: My University
Year: 2021
Subjects: subject: Efferocytosis
subject: Peripheral Nerve Injury
subject: Macrophage Polarization
subject: Neuroinflammation
subject: Sciatic Nerve
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Health Sciences

description: Evolutionarily, the nervous system and immune system have been intertwined for hundreds of millions of years. In healthy conditions, these systems work diligently to maintain homeostasis and proper functioning. In summation, they keep our bodies moving, our organs operating, our minds thinking, and our bodies safe from foreign pathogenic invaders. However, in the event of a challenge to homeostasis, like a traumatic injury, both systems engage complex signaling cascades to degenerate parts of cells that can’t be saved, protect those that can, remove harmful debris, and regenerate and repair to again obtain homeostasis. A common system to study these complex response mechanisms is that of a peripheral nerve injury. My research over the past several years has been focused around fully understanding the complex immune-nerve communication and consequences that occur following peripheral nerve injury. The work herein keenly elaborates on the time course and content of the immune response after peripheral nerve crush injury. We show that granulocytes are the first to respond with infiltrating monocytes entering a few days later and finally dendritic cells about a week after injury. We however show little evidence of significant immune infiltration into dorsal root ganglia of the sciatic nerve and rather DRG-resident immune cell morphological changes. It is also demonstrated that mesenchymal progenitor cells are key in shaping the inflammatory milieu after injury. The requirement of Csf2 for conditioning-lesion-induced dorsal column axon regeneration is evidenced as well as its role in skewing the inflammatory response. The dynamicity of the immune non-immune responses to nerve injury in wild-type an SARM1 knockout animals at multiple timepoints is compared and contrasted. Finally, we are the first group to show the occurrence of efferocytosis (the phagocytosis of apoptotic cells) in the injured nerve, identify a specific transcriptomic identity for macrophages engaged in this action, and investigate the anti-inflammatory signaling this process propagates.
КОМПЛЕКСНАЯ ДИАГНОСТИКА РАЗЛИЧНЫХ ТИПОВ РУБЦОВЫХ ДЕФОРМАЦИЙ ГОЛОВЫ И ШЕИ НА ОСНОВАНИИ РЕЗУЛЬТАТОВ ЛАЗЕРНОЙ ФЛУОРЕСЦЕНТНОЙ СПЕКТРОСКОПИИ IN VIVO
Creators: name: АНДРЕЕВА В.В.
name: СИПКИН А.М.
name: РАЗНИЦЫНА И.А.
name: РОГАТКИН Д.А.
name: КУЛИКОВ Д.А.
Publisher: name: Трудный пациент
Year: 2019
Subjects: РУБЦОВЫЕ ДЕФОРМАЦИИ
РУБЦЫ
ЛАЗЕРНАЯ ФЛУОРЕСЦЕНТНАЯ СПЕКТРОСКОПИЯ
ЛИПОФУСЦИН
КОЛЛАГЕН
НЕИНВАЗИВНАЯ ДИАГНОСТИКА РУБЦОВ

description: Проанализированы данные лазерной флуресцентной спектроскопии in vivo у пациентов с различными типами рубцовых деформаций в области головы и шеи. Была обнаружена пониженная эндогенная флуоресценция липофусцина в здоровой коже у пациентов с келоидным рубцом, что статистически отличало от данных липофусцина у пациентов с гипертрофическими и нормотрофическими рубцами. Вероятно, такие изменения говорят о трансформации окислительно-восстановительного баланса в клетках. Предположительно, также происходят нарушения процессов протеолиза и клеточной гибели. Следовательно, на основании анализа эндогенной флуоресценции здоровой кожи можно предположить о вероятности развития келоидного рубца, учитывая данные неинвазивного метода исследования интактной ткани.
O relacionamento do McDonald's no Facebook com Brasileiros e Portugueses
Creators: name: Moraes, Naiara Back De
name: Santor, Fernando
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: Este estudo é resultado de uma pesquisa bibliográfica e da análise de conteúdo nas fanpages do McDonald’s Brasil e Portugal, onde busca-se, por meio de análise comparativo entre os cinco posts mais compartilhados no mês de julho de 2013, compreender as estratégias de relacionamento e interação nas redes sociais.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
A utilização da Infografia nas secções de Ciência e Tecnologia de quatro Jornais On-line nacionais
Creators: name: Pereira, Filipa Rodrigues Ramos
name: Oliveira, Lídia
name: Zamith, Fernando
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: A generalização do uso da Internet fez com que os jornais passassem a ter uma versão on-line das suas edições. O formato digital, pela sua natureza, permite uma riqueza de linguagem gráfica muito maior, sem limite ao nível cromático, ao nível da definição e complexidade das imagens e dos infográficos, que podem ser estáticos ou dinâmicos, bi ou tri-dimensionais. Face a este novo contexto de comunicação pretende-se, compreender o nível de uso da infografia nas secções de ciência e tecnologia de quatro jornais portugueses (“Jornal de Notícias”; “Público”; “Expresso” e “i”) nas suas versões on-line. Por outro lado tentar-se-á perceber de que forma essa utilização pode promover o consumo de conteúdos informativos de ciência e tecnologia e, deste modo, contribuir para melhorar o índice de compreensão e aquisição de informação dos seus consumidores. Este trabalho visa a apresentação e divulgação de um projeto de investigação centrado na compreensão do papel da infografia na apreensão de conteúdos noticiosos sobre ciência e tecnologia. Apresenta-se também o modelo metodológico que será adoptado na investigação bem como os resultados de uma análise preliminar feita aos quatro jornais seleccionados para este estudo no que respeita à publicação de infográficos de ciência e tecnologia.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
Teaching introductory undergraduate Physics using commercial video games
Creators: name: Mohanty, Soumya D.
name: Cantu, Sergio
Publisher: name: arXiv
Year: 2011
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: Commercial video games are increasingly using sophisticated physics simulations to create a more immersive experience for players. This also makes them a powerful tool for engaging students in learning physics. We provide some examples to show how commercial off-the-shelf games can be used to teach specific topics in introductory undergraduate physics. The examples are selected from a course taught predominantly through the medium of commercial video games.
description: Accepted to Physics Education, Fig1 does not render properly in this version
title: Präferenz von linearen Regressionsmodellen bei Kindern – Ergebnisse einer ersten Pilotstudie
Creators: name: Maußner, Nadine
name: Ostermann, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Statistical methods in epidemiology
subject: Statistical methods for health services research
subject: Statistical techniques for systems biology and systems medicine
subject: 610 Medical sciences; Medicine

description: Hintergrund: Die univariate lineare Regression ist eine statistische Methode, um Geraden der Form y=bx+t an gegebene Datenpaare (x1,y1),...,(xN,yN) anzupassen. Die am häufigsten verwandte Methode ist die der Ordinary Least Square-Methode (OLS(X|Y)), bei der Y als abhängige und[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: HEC 2016: Health – Exploring Complexity; Joint Conference of GMDS, DGEpi, IEA-EEF, EFMI
ТРУДНОСТИ НА ПУТИ ДИАГНОСТИКИ И ЛЕЧЕНИЯ САРКОИДОЗА. ПО МАТЕРИАЛАМ КОНГРЕССА "ЧЕЛОВЕК И ЛЕКАРСТВО" И III САММИТА ПУЛЬМОНОЛОГОВ
Creators: name: По материалам Конгресса
Publisher: name: Трудный пациент
Year: 2019
Subjects: АРКОИДОЗ
ГРАНУЛЕМА
СИНДРОМ ЛЕФГРЕНА
СИНДРОМ ХЕЕРФОРДТА-ВАЛЬДЕНСТРЕМА
АНГИОТЕНЗИНПРЕВРАЩАЮЩИЙ ФЕРМЕНТ
ГЛЮКОКОРТИКОСТЕРОИДЫ
МЕТОТРЕКСАТ
SARCOIDOSIS
GRANULOMA
LOFGREN SYNDROME
HEERFORD-WALDENSTROM SYNDROME
ANGIOTENSIN-CONVERTING ENZYME
GLUCOCORTICOSTEROIDS
METHOTREXATE

description: Саркоидоз представляет собой системное воспалительное заболевание, проявляющееся мультисистемным поражением различных органов. Заболеваемость в России составляет 27-47 человек на 100 тыс. человек. Диагноз саркоидоза ставится на основании 3 критериев: соответствующая клиническая и радиологическая картина; гистологически подтвержденная неказеифицирующаяся гранулема; отсутствие альтернативного диагноза. Терапия назначается в соответствии со стадией заболевания. У бессимптомных больных с I или II стадией саркоидоза лечение не показано ввиду высокой частоты спонтанной ремиссии. У больных с прогрессирующим течением болезни II и III стадии, при выраженных симптомах или внелегочных проявлениях, нарушающих функцию органа, препаратами выбора являются глюкокортикостероиды. В качестве терапии второй линии используется метотрексат.
A reinvenção do Jornalismo: Tecnologia mudando a forma de produzir e fazer Jornalismo
Creators: name: Assumpção, Douglas Junio Fernandes
name: Villegas, Greicy Marianne Lopes G. C.
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: As coisas mudam com o tempo. O jornalismo também. As práticas de apuração e publicação são as mesmas de outrora, os meios é que são diversos hoje. E é preciso avançar com cautela frente às novas tecnologias da comunicação social. A tecnologia sempre esteve presente na história do jornalismo. Desde o surgimento do papiro, do telefone, passando pelas saudosas máquinas de escrever, até a utilização da realidade virtual para contar um fato, o jornalismo nunca passou despercebido pelas introduções das tecnologias no seu fazer. Sempre que houve uma nova maneira de captar informação, produzir ou distribuir conteúdo, o jornalismo teve seu processo afetado. Aspecto que merece ser estudado, como se propõe nesta pesquisa, é a necessidade de assimilar a alta velocidade informativa imposta pela sociedade do “agora” a partir do advento de novas tecnologias na comunicação social. Nosso desafio é contribuir com conhecimento de campo e comparar estudos recentes e consagradas pesquisas teóricas. Levando-nos a refletir acerca de como o advento das novas tecnologias na comunicação televisiva faz com que os jornalistas de tevê adquiram habilidade para a atualização constante da notícia minuto-a-minuto e a versatilidade na apuração dos fatos em tempo real.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"
O fazer jornalístico e o enfrentamento de cenários complexos inaugurais
Creators: name: Bruck, Mozahir Salomão
name: Santos, Bruna Raquel De Oliveira E
Publisher: name: SOPCOM: Associação Portuguesa de Ciências da Comunicação
Year: 2013

description: O artigo busca refletir sobre desafios e dificuldades que o fazer jornalístico enfrenta diante do surgimento e desenvolvimento de circunstâncias/situações complexas que impactam a sociedade estabelecendo, geralmente, novos parâmetros de compreensão e de abordagens de tais temas/assuntos. Tais contextos estabelecem, no tecido social, novos paradigmas de comportamento individual e coletivo e, muitas vezes, reorientando as relações sociais. Nossos focos de observação foram como jornais brasileiros se portaram diante do aparecimento e posterior explosão da Aids, na metade da década de 1980, e da droga crack, que teve seu primeiro registro no Brasil no final dessa mesma década. A hipótese é que diante de novos quadros de realidade e de suas exigências de explicação, o trabalho jornalístico tende a se desenrolar em circunstâncias de instabilidade, em função de incertezas, generalizações e mitificações – que se instalam nas lacunas abertas pela impossibilidade inicial de melhor compreensão de tais processos.
description: SOPCOM: Associação Portuguesa de Ciências da Comunicação, 2013: 8º SOPCOM: "Comunicação Global, Cultura e Tecnologia"