cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Smart wearable body sensors for patient self-assessment and monitoring
Creators: name: Appelboom, Geoff
name: Camacho, Elvis
name: Abraham, Mickey E.
name: Bruce, Samuel S.
name: Dumont, Emmanuel L. P.
name: Zacharia, Brad E.
name: D’Amico, Randy
name: Slomian, Justin
name: Reginster, Jean Yves
name: Bruyère, Olivier
name: Connolly Jr., E. Sander
Publisher: name: Columbia University
Year: 2014
Subjects: Medical care
Medical technology
Patient self-monitoring
Medical sciences

description: Background:
Innovations in mobile and electronic healthcare are revolutionizing the involvement of both doctors and patients in the modern healthcare system by extending the capabilities of physiological monitoring devices. Despite significant progress within the monitoring device industry, the widespread integration of this technology into medical practice remains limited. The purpose of this review is to summarize the developments and clinical utility of smart wearable body sensors.

Methods:
We reviewed the literature for connected device, sensor, trackers, telemonitoring, wireless technology and real time home tracking devices and their application for clinicians.

Results:
Smart wearable sensors are effective and reliable for preventative methods in many different facets of medicine such as, cardiopulmonary, vascular, endocrine, neurological function and rehabilitation medicine. These sensors have also been shown to be accurate and useful for perioperative monitoring and rehabilitation medicine.

Conclusion:
Although these devices have been shown to be accurate and have clinical utility, they continue to be underutilized in the healthcare industry. Incorporating smart wearable sensors into routine care of patients could augment physician-patient relationships, increase the autonomy and involvement of patients in regards to their healthcare and will provide for novel remote monitoring techniques which will revolutionize healthcare management and spending.

Keywords:

Sensors Mobile health eHealth Patient education Quantified patient
Hydrochaeris hydrochaeris
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Hydrochaeridae
Hydrochaeris
Hydrochaeris hydrochaeris

description: Hydrochaeris hydrochaeris (Linnaeus, 1766). Syst. Nat., 12th ed., 1:103. TYPE LOCALITY: Surinam. DISTRIBUTION: Panama, Colombia, Venezuela, the Guyanas and Peru, south through Brazil, Paraguay, N.E. Argentina, and Uruguay. COMMENT: Includes isthmius; see Handley, 1966, in Wenzel and Tipton, eds., Ectoparasites of Panama, p. 785. Cabrera, 1961:583, gave Pernambuco, Brazil as the type locality, but see Husson, 1978:451, for restriction. ISIS NUMBER: 5301410020001001001 as H. hydrochaeris. 5301410020001002001 as H. isthmius.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 575, DOI: 10.5281/zenodo.7353039
description: {"references": ["Husson, A. M. 1978. The mammals of Suriname. E. J. Brill, Leiden, 569 pp., 160 pls."]}
Heptaxodontidae Anthony 1917
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Heptaxodontidae

description: Family Heptaxodontidae COMMENT: Known only from sub-Recent fossils from Greater and N. Lesser Antilles; see Hall, 1981:855-856.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 575, DOI: 10.5281/zenodo.7353039
description: {"references": ["Hall, E. R. 1981. The mammals of North America. Second ed. John Wiley and Sons, New York, 1: 1 - 600 + 90, 2: 601 - 1181 + 90."]}
Overview of the mental health system in Mozambique: addressing the treatment gap with a task-shifting strategy in primary care
Creators: name: Fortunado Dos Santos, Palmira
name: Wainberg, Milton L.
name: Caldas-De-Almeida, José Miguel
name: Saraceno, Benedetto
name: Mari, Jair De Jesus
Publisher: name: Columbia University
Year: 2016
Subjects: subject: Mental health facilities
subject: Mental health policy
subject: Mental health services
subject: Psychology
subject: FOS: Psychology
subject: Social psychology

description: Background
Mozambique has gradually changed its action on mental health (MH) from an asylum-centric care with long-term hospitalization to an innovative approach to community and primary care.

Objective
To collect essential information on Mozambique’s MH system for decision making, to improve quality of services delivered, update MH Strategy and Action Plan.

Method
The study used the WHO-AIMS to assess MH systems including policy and legislation, organization of services, MH in primary care, human resources, public education and link with other sectors, monitoring and research. A comparative analysis was conducted to present the evolution of relevant data from 2010 to 2014.

Results
There are two psychiatric hospitals in the country and beds in general hospitals. In the period, the number of beds in general hospitals remained stable (203), and the beds in psychiatric hospitals increased from 173 to 298. Mental health outpatient facilities have increased from 83 to 152. The number of psychiatrists (9 in 2010, and 10 in 2014) remained very low, with a significant increase in the number of psychologists (56–109) and occupational therapists (2–23). The number of Psychiatric Technicians has increased from 66 in 2010, to 241 in 2014. This increase allowed the mental health network to expand from 60 to 135 Districts, meaning an increase of coverage from 44 to 100 % of the country districts.

Conclusion
The task-shifting strategy focused on services delivered in primary care by psychiatric technicians, mid-level professionals, allowed the expansion of mental health services for all the country districts and the reduction of treatment gap in Mozambique.
title: Obtaining water level data at Whakarewarewa Geothermal Valley using unmanned aerial vehicle photogrammetry
Creators: name: Macdonald, Nick
name: Reeves, Robert R.
name: Graham, Duncan J.
name: Brakenrig, Thomas
Publisher: name: GNS Science
Year: 2019

description: Unmanned aerial vehicles (UAVs) offer a novel means of studying dangerous and inaccessible areas. They have the advantage of having the ability to survey large study areas relatively quickly, while utilising a wide array of sensors. Monitoring the water level of geothermal pools is important for providing insight into how fluids may be flowing and interacting between geothermal surface features and shallow groundwater aquifers. Making manual measurements of water levels in geothermal areas can be either impossible or hazardous due to factors such as unstable ground, dangerous gas concentrations, hot water and hot ground. In this study, a method for measuring water levels of geothermal pools using an UAV was developed to produce a potentiometric map of the shallowest groundwater surface, across the Whakarewarewa Geothermal Valley, Rotorua. Methods for estimating the elevation of the water surface of geothermal pools from high-resolution aerial photography were evaluated. We found that the uncertainty of deriving water elevations of pools was primarily affected by non-random photogrammetric point errors that occurred across the central parts of pools, and by the physical characteristics of geothermal pools such as upwelling of source fluid, ebullition (boiling) and water clarity. These physical characteristics adversely affected the image processing. The accuracy of the water level elevations was greatly improved when using photogrammetric pixels located at the edges of the pools. Therefore, point data with DSM1 was used to obtain water surface elevations from a selection of geothermal pools and generate a potentiometric map. The resulting potentiometric map of Whakarewarewa Geothermal Valley shows a southwest/northeast orientated area of elevated water levels. This occurs at higher ground elevation on the southern side of the valley, in an area containing steam-fed, acid-sulphate pools. The potentiometric map provides some insights into possible perched groundwater aquifers, and probable groundwater flow characteristics, in the area. This preliminary study on using UAVs to measure water level elevations of geothermal pools looks promising, however, a clear understanding and control of uncertainty in the data is critical to develop a reliable interpretation of results. (auth)
Figures S1 and S2 from People, primates and predators in the Pontal: from endangered species conservation to forest and landscape restoration in Brazil's Atlantic Forest
Creators: name: Chazdon, Robin L.
name: Cullen, Laury
name: Padua, Suzana M.
name: Padua, Claudio Valladares
Publisher: name: The Royal Society
Year: 2020
Subjects: Environmental Science

description: Google Earth images of the changing Pontal do Parapanema landscape from 1984 to 2016;IPÊ’s model of conservation
High Field determination of superconducting fluctuations in high-Tc cuprates
Creators: name: Rullier-Albenque, F.
name: Alloul, H.
name: Colson, D.
name: Forget, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Large pulsed magnetic fields up to 60 Tesla are used to suppress the contribution of superconducting fluctuations (SCF) to the ab-plane conductivity above Tc in a series of YBa2Cu3O6+x single crystals. The fluctuation conductivity is found to vanish nearly exponentially with temperature, allowing us to determine precisely the field H'c(T) and the temperature T'c above which the SCFs are fully suppressed. T'c is always found much smaller than the pseudogap temperature. A careful investigation near optimal doping shows that T'c is higher than the pseudogap T*, which indicates that the pseudogap cannot be assigned to preformed pairs. For nearly optimally doped samples, the fluctuation conductivity can be accounted for by gaussian fluctuations following the Ginzburg-Landau scheme. A phase fluctuation contribution might be invoked for the most underdoped samples in a T range which increases when controlled disorder is introduced by electron irradiation. Quantitative analysis of the fluctuating magnetoconductance allows us to determine the critical field Hc2(0) which is found to be quite similar to H'c(0) and to increase with hole doping. Studies of the incidence of disorder on both T'c and T* enable us to propose a three dimensional phase diagram including a disorder axis, which allows to explain most observations done in other cuprate families.
description: 10 pages, 10 figures, invited paper at the M2SHTSC Conference Washington (2012)
Adolescent Female Text Messaging Preferences to Prevent Pregnancy After an Emergency Department Visit: A Qualitative Analysis
Creators: name: Chernick, Lauren
name: Schnall, Rebecca
name: Stockwell, Melissa
name: Castano, Paula M.
name: Higgins, Tracy
name: Westhoff, Carolyn Louise
name: Santelli, John S.
name: Dayan, Peter
Publisher: name: Columbia University
Year: 2016
Subjects: Teenage pregnancy
Teenage pregnancy--Prevention
Text messages (Cell phone systems)
Emergency medical services
Public health

description: Background: Over 15 million adolescents use the emergency department (ED) each year in the United States. Adolescent females who use the ED for medical care have been found to be at high risk for unintended pregnancy. Given that adolescents represent the largest users of text messaging and are receptive to receiving text messages related to their sexual health, the ED visit represents an opportunity for intervention.
Objective: The aim of this qualitative study was to explore interest in and preferences for the content, frequency, and timing of an ED-based text message intervention to prevent pregnancy for adolescent females.
Methods: We conducted semistructured, open-ended interviews in one urban ED in the United States with adolescent females aged 14-19 years. Eligible subjects were adolescents who were sexually active in the past 3 months, presented to the ED for a reproductive health complaint, owned a mobile phone, and did not use effective contraception. Using an interview guide, enrollment continued until saturation of key themes. The investigators designed sample text messages using the Health Beliefs Model and participants viewed these on a mobile phone. The team recorded, transcribed, and coded interviews based on thematic analysis using the qualitative analysis software NVivo and Excel.
Results: Participants (n=14) were predominantly Hispanic (13/14; 93%), insured (13/14; 93%), ED users in the past year (12/14; 86%), and frequent text users (10/14; 71% had sent or received >30 texts per day). All were interested in receiving text messages from the ED about pregnancy prevention, favoring messages that were “brief,” “professional,” and “nonaccusatory.” Respondents favored texts with links to websites, repeated information regarding places to receive “confidential” care, and focused information on contraception options and misconceptions. Preferences for text message frequency varied from daily to monthly, with random hours of delivery to maintain “surprise.” No participant feared that text messages would violate her privacy.
Conclusions: Adolescent female patients at high pregnancy risk are interested in ED-based pregnancy prevention provided by texting. Understanding preferences for the content, frequency, and timing of messages can guide in designing future interventions in the ED.
British Columbia Legislative Assembly sessional clipping book (1892-02)
Creators: name: :Unav
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: British Columbia. Legislative Assembly
valueUri: http://id.worldcat.org/fast/600765
subject: Law
valueUri: http://id.worldcat.org/fast/993678
subject: FOS: Law
subject: Politics and government
valueUri: http://id.worldcat.org/fast/1919741

description: These Sessional Clippings books cover the period 1891 to 1972, and include newspaper accounts written by various legislative reporters who covered debates occurring in the British Columbia Legislative Assembly. Transcripts of debates of the Legislative Assembly (Hansard) were not published in B.C. until 1970; hence these "Sessional Clipping Books" augment the "Journals", the record of daily proceedings of the Legislative Assembly. Selected clippings from various newspapers including the Vancouver Sun, the Vancouver Province, the Colonist, and the Times newspapers, relating to the newspaper reports concerning activities of the Legislature. The original sessional clippings books comprise 351 ledger size print volumes, held at the Legislative Library in Victoria BC. The print volumes were microfilmed onto 26 reels in 1977 under a Tri University Libraries (TRIUL) project by Precision Micrographic Services (Vancouver, B.C.), with the permission of the Legislative Library, Victoria, British Columbia. This digital collection was created by scanning the 26 microfilm reels.
The Receptor for Advanced Glycation End Products (RAGE) Affects T Cell Differentiation in OVA Induced Asthma
Creators: name: Akirav, Eitan A.
name: Henegariu, Octavian
name: Preston-Hurlburt, Paula
name: Schmidt, Anne Marie
name: Clynes, Raphael A.
name: Herold, Kevan C.
Publisher: name: Columbia University
Year: 2014
Subjects: T cells
T cells--Differentiation
Immune response
Glycosylation
Medicine

description: The receptor for glycation end products (RAGE) has been previously implicated in shaping the adaptive immune response. RAGE is expressed in T cells after activation and constitutively in T cells from patients with diabetes. The effects of RAGE on adaptive immune responses are not clear: Previous reports show that RAGE blockade affects Th1 responses. To clarify the role of RAGE in adaptive immune responses and the mechanisms of its effects, we examined whether RAGE plays a role in T cell activation in a Th2 response involving ovalbumin (OVA)-induced asthma in mice. WT and RAGE deficient wild-type and OT-II mice, expressing a T cell receptor specific for OVA, were immunized intranasally with OVA. Lung cellular infiltration and T cell responses were analyzed by immunostaining, FACS, and multiplex bead analyses for cytokines. RAGE deficient mice showed reduced cellular infiltration in the bronchial alveolar lavage fluid and impaired T cell activation in the mediastinal lymph nodes when compared with WT mice. In addition, RAGE deficiency resulted in reduced OT-II T cell infiltration of the lung and impaired IFNγ and IL-5 production when compared with WT mice and reduced infiltration when transferred into WT hosts. When cultured under conditions favoring the differentiation of T cells subsets, RAGE deficient T cells showed reduced production of IFNγ but increased production of IL-17. Our data show a stimulatory role for RAGE in T activation in OVA-induced asthma. This role is largely mediated by the effects of RAGE on T cell proliferation and differentiation. These findings suggest that RAGE may play a regulatory role in T cell responses following immune activation.
Dinomyidae Peters 1873
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Dinomyidae

description: Family Dinomyidae REVIEWED BY: M. A. Mares (MAM); T. Pearson (TP); C. A. Woods (CAW). ISIS NUMBER: 5301410021000000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 575, DOI: 10.5281/zenodo.7353039
Provider-Initiated HIV Testing and Counselling in Rwanda: Acceptability among Clinic Attendees and Workers, Reasons for Testing and Predictors of Testing
Creators: name: Kayigamba, Felix R.
name: Bakker, Mirjam I.
name: Mugisha, Veronicah
name: Lammers, Judith
name: Bagiruwigize, Emmanuel
name: Asiimwe, Anita
name: Schim Van Der Loeff, Maarten F.
Publisher: name: Columbia University
Year: 2014
Subjects: HIV (Viruses)--Diagnosis
HIV infections--Epidemiology
Public health
AIDS (Disease)--Epidemiology
AIDS (Disease)--Testing
AIDS (Disease)--Diagnosis
HIV (Viruses)--Testing
Medicine
Epidemiology

description: Introduction: Routine provider-initiated HIV testing and counselling (PITC) may increase HIV testing rates, but whether PITC is acceptable to health facility (HF) attendees is unclear. In the course of a PITC intervention study in Rwanda, we assessed the acceptability of PITC, reasons for being or not being tested and factors associated with HIV testing.

Methods: Attendees were systematically interviewed in March 2009 as they left the HF, regarding knowledge and acceptability of PITC, history of testing and reasons for being tested or not. Subsequently, PITC was introduced in 6 of the 8 HFs and a second round of interviews was conducted. Independent factors associated with testing were analysed using logistic regression. Randomly selected health care workers (HCWs) were also interviewed.

Results: 1772 attendees were interviewed. Over 95% agreed with the PITC policy, both prior to and after implementation of PITC policy. The most common reasons for testing were the desire to know one’s HIV status and having been offered an HIV test by an HCW. The most frequent reasons for not being tested were known HIV status and test not being offered. In multivariable analysis, PITC, age ≥15 years, and not having been previously tested were factors significantly associated with testing. Although workload was increased by PITC, HIV testing rates increased and HCWs overwhelmingly supported the policy.

Conclusion: Among attendees and HCWs in Rwandan clinics, the acceptability of PITC was very high. PITC appeared to increase testing rates and may be helpful in prevention and early access to treatment.
Community Care Workers, Poor Referral Networks and Consumption of Personal Resources in Rural South Africa
Creators: name: Sips, Ilona
name: Mazanderani, Ahmad Haeri
name: Schneider, Helen
name: Greeff, Minrie
name: Barten, Francoise
name: Moshabela, Mosa
Publisher: name: Columbia University
Year: 2014
Subjects: Home care services--Standards
Home care services--Employees
Home care services--Administration
Business referrals
Community health services
Home care services
Health services administration
Medical care
Medicine

description: Although home-based care (HBC) programs are widely implemented throughout Africa, their success depends on the existence of an enabling environment, including a referral system and supply of essential commodities. The objective of this study was to explore the current state of client referral patterns and practices by community care workers (CCWs), in an evolving environment of one rural South African sub-district. Using a participant triangulation approach, in-depth qualitative interviews were conducted with 17 CCWs, 32 HBC clients and 32 primary caregivers (PCGs). An open-ended interview guide was used for data collection. Participants were selected from comprehensive lists of CCWs and their clients, using a diversified criterion-based sampling method. Three independent researchers coded three sets of data – CCWs, Clients and PCGs, for referral patterns and practices of CCWs. Referrals from clinics and hospitals to HBC occurred infrequently, as only eight (25%) of the 32 clients interviewed were formally referred. Community care workers showed high levels of commitment and personal investment in supporting their clients to use the formal health care system. They went to the extent of using their own personal resources. Seven CCWs used their own money to ensure client access to clinics, and eight gave their own food to ensure treatment adherence. Community care workers are essential in linking clients to clinics and hospitals and to promote the appropriate use of medical services, although this effort frequently necessitated consumption of their own personal resources. Therefore, risk protection strategies are urgently needed so as to ensure sustainability of the current work performed by HBC organizations and the CCW volunteers.
The Volatile Anesthetic Isoflurane Increases Endothelial Adenosine Generation via Microparticle Ecto-5′-Nucleotidase (CD73) Release
Creators: name: Kim, Mihwa
name: Ham, Ahrom
name: Kim, Katelyn Yu-Mi
name: Brown, Kevin M.
name: Lee, H. Thomas
Publisher: name: Columbia University
Year: 2014
Subjects: Isoflurane
Endothelial cells
Adenosine
Molecular biology
Medicine

description: Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation. In this study, we tested whether isoflurane induces endothelial ecto-5′-nucleotidase (CD73) and cytoprotective adenosine generation to protect against endothelial cell injury. Clinically relevant concentrations of isoflurane induced CD73 activity and increased adenosine generation in cultured human umbilical vein or mouse glomerular endothelial cells. Surprisingly, isoflurane-mediated induction of endothelial CD73 activity occurred within 1 hr and without synthesizing new CD73. We determined that isoflurane rapidly increased CD73 containing endothelial microparticles into the cell culture media. Indeed, microparticles isolated from isoflurane-treated endothelial cells had significantly higher CD73 activity as well as increased CD73 protein. In vivo, plasma from mice anesthetized with isoflurane had significantly higher endothelial cell-derived CD144+ CD73+ microparticles and had increased microparticle CD73 activity compared to plasma from pentobarbital-anesthetized mice. Supporting a critical role of CD73 in isoflurane-mediated endothelial protection, a selective CD73 inhibitor (APCP) prevented isoflurane-induced protection against human endothelial cell inflammation and apoptosis. In addition, isoflurane activated endothelial cells Rho kinase evidenced by myosin phosphatase target subunit-1 and myosin light chain phosphorylation. Furthermore, isoflurane-induced release of CD73 containing microparticles was significantly attenuated by a selective Rho kinase inhibitor (Y27632). Taken together, we conclude that the volatile anesthetic isoflurane causes Rho kinase-mediated release of endothelial microparticles containing preformed CD73 and increase adenosine generation to protect against endothelial apoptosis and inflammation.
Mutations in the Cholesterol Transporter Gene ABCA5 Are Associated with Excessive Hair Overgrowth
Creators: name: DeStefano, Gina Marie
name: Kurban, Mazen
name: Anyane-Yeboa, Kwame
name: Dall'Armi, Claudia
name: Di Paolo, Gilbert
name: Feenstra, Heather
name: Silverberg, Nanette
name: Rohena, Luis
name: López-Cepeda, Larissa D.
name: Jobanputra, Vaidehi
name: Fantauzzo, Katherine A.
name: Kiuru, Maija
name: Tadin-Strapps, Marija
name: Sobrino, Antonio
name: Vitebsky, Anna
name: Warburton, Dorothy
name: Levy, Brynn
name: Salas-Alanis, Julio C.
name: Christiano, Angela M.
Publisher: name: Columbia University
Year: 2014
Subjects: subject: Mutation (Biology)
subject: Keratinocytes
subject: Hypertrichosis
subject: Genetics
subject: FOS: Biological sciences
subject: Biology

description: Inherited hypertrichoses are rare syndromes characterized by excessive hair growth that does not result from androgen stimulation, and are often associated with additional congenital abnormalities. In this study, we investigated the genetic defect in a case of autosomal recessive congenital generalized hypertrichosis terminalis (CGHT) (OMIM135400) using whole-exome sequencing. We identified a single base pair substitution in the 5′ donor splice site of intron 32 in the ABC lipid transporter gene ABCA5 that leads to aberrant splicing of the transcript and a decrease in protein levels throughout patient hair follicles. The homozygous recessive disruption of ABCA5 leads to reduced lysosome function, which results in an accumulation of autophagosomes, autophagosomal cargos as well as increased endolysosomal cholesterol in CGHT keratinocytes. In an unrelated sporadic case of CGHT, we identified a 1.3 Mb cryptic deletion of chr17q24.2-q24.3 encompassing ABCA5 and found that ABCA5 levels are dramatically reduced throughout patient hair follicles. Collectively, our findings support ABCA5 as a gene underlying the CGHT phenotype and suggest a novel, previously unrecognized role for this gene in regulating hair growth.
title: Mariane von Terville; 1778
title: eine Erzählung ; Aus einer französischen Handschrift übersetzt
titleType: Subtitle
Creators: name: Marivaux, Pierre Carlet de Chamblain de
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2015

description: In Fraktur. - Mutmaßl. Verf.: Marivaux, Pierre Carlet de Chamblain de: Mariane von Terville
Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
Creators: name: Embree, Mildred C.
name: Chen, Mo
name: Pylawka, Serhiy
name: Kong, Danielle
name: Iwaoka, George M.
name: Kalajzic, Ivo
name: Yao, Hai
name: Shi, Chancheng
name: Sun, Dongming
name: Sheu, Tzong-Jen
name: Koslovsky, David A.
name: Koch, Alia
name: Mao, Jeremy J.
Publisher: name: Columbia University
Year: 2016
Subjects: Stem cells
Temporomandibular joint
Cartilage--Regeneration
Medicine

description: Tissue regeneration using stem cell-based transplantation faces many hurdles. Alternatively, therapeutically exploiting endogenous stem cells to regenerate injured or diseased tissue may circumvent these challenges. Here we show resident fibrocartilage stem cells (FCSCs) can be used to regenerate and repair cartilage. We identify FCSCs residing within the superficial zone niche in the temporomandibular joint (TMJ) condyle. A single FCSC spontaneously generates a cartilage anlage, remodels into bone and organizes a haematopoietic microenvironment. Wnt signals deplete the reservoir of FCSCs and cause cartilage degeneration. We also show that intra-articular treatment with the Wnt inhibitor sclerostin sustains the FCSC pool and regenerates cartilage in a TMJ injury model. We demonstrate the promise of exploiting resident FCSCs as a regenerative therapeutic strategy to substitute cell transplantation that could be beneficial for patients suffering from fibrocartilage injury and disease. These data prompt the examination of utilizing this strategy for other musculoskeletal tissues.
Persistence of locality in systems with power-law interactions
Creators: name: Gong, Zhe-Xuan
name: Foss-Feig, Michael
name: Michalakis, Spyridon
name: Gorshkov, Alexey V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Motivated by recent experiments with ultra-cold matter, we derive a new bound on the propagation of information in $D$-dimensional lattice models exhibiting $1/r^α$ interactions with $α>D$. The bound contains two terms: One accounts for the short-ranged part of the interactions, giving rise to a bounded velocity and reflecting the persistence of locality out to intermediate distances, while the other contributes a power-law decay at longer distances. We demonstrate that these two contributions not only bound but, except at long times, \emph{qualitatively reproduce} the short- and long-distance dynamical behavior following a local quench in an $XY$ chain and a transverse-field Ising chain. In addition to describing dynamics in numerous intractable long-range interacting lattice models, our results can be experimentally verified in a variety of ultracold-atomic and solid-state systems.
description: 5 pages, 4 figures, version accepted by PRL
Ten-Year Trends in Coronary Calcification in Individuals without Clinical Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis
Creators: name: Bild, Diane E.
name: McClelland, Robyn
name: Kaufman, Joel D.
name: Blumenthal, Roger
name: Burke, Gregory L.
name: Carr, J. Jeffrey
name: Post, Wendy S.
name: Register, Thomas C.
name: Shea, Steven J. C.
name: Szklo, Moyses
Publisher: name: Columbia University
Year: 2014
Subjects: Coronary arteries--Calcification
Atherosclerosis
Atherosclerosis--Risk factors
African Americans--Diseases
Coronary heart disease
Medicine

description: Background: Coronary heart disease (CHD) incidence has declined significantly in the US, as have levels of major coronary risk factors, including LDL-cholesterol, hypertension and smoking, but whether trends in subclinical atherosclerosis mirror these trends is not known.

Methods and Findings: To describe recent secular trends in subclinical atherosclerosis as measured by serial evaluations of coronary artery calcification (CAC) prevalence in a population over 10 years, we measured CAC using computed tomography (CT) and CHD risk factors in five serial cross-sectional samples of men and women from four race/ethnic groups, aged 55–84 and without clinical cardiovascular disease, who were members of Multi-Ethnic Study of Atherosclerosis (MESA) cohort from 2000 to 2012. Sample sizes ranged from 1062 to 4837. After adjusting for age, gender, and CT scanner, the prevalence of CAC increased across exams among African Americans, whose prevalence of CAC was 52.4% in 2000–02, 50.4% in 2003–04, 60.0% is 2005–06, 57.4% in 2007–08, and 61.3% in 2010–12 (p for trend <0.001). The trend was strongest among African Americans aged 55–64 [prevalence ratio for 2010–12 vs. 2000–02, 1.59 (95% confidence interval 1.06, 2.39); p = 0.005 for trend across exams]. There were no consistent trends in any other ethnic group. Risk factors generally improved in the cohort, and adjustment for risk factors did not change trends in CAC prevalence.

Conclusions: There was a significant secular trend towards increased prevalence of CAC over 10 years among African Americans and no change in three other ethnic groups. Trends did not reflect concurrent general improvement in risk factors. The trend towards a higher prevalence of CAC in African Americans suggests that CHD risk in this population is not improving relative to other groups.
Abstract interpretation-based approaches to Security - A Survey on Abstract Non-Interference and its Challenging Applications
Creators: name: Mastroeni, Isabella
Publisher: name: arXiv
Year: 2013
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: In this paper we provide a survey on the framework of abstract non-interference. In particular, we describe a general formalization of abstract non-interference by means of three dimensions (observation, protection and semantics) that can be instantiated in order to obtain well known or even new weakened non-interference properties. Then, we show that the notions of abstract non-interference introduced in language-based security are instances of this more general framework which allows to better understand the different components of a non-interference policy. Finally, we consider two challenging research fields concerning security where abstract non-interference seems a promising approach providing new perspectives and new solutions to open problems: Code injection and code obfuscation.
description: In Proceedings Festschrift for Dave Schmidt, arXiv:1309.4557
Gel Formation in Protein Amyloid Aggregation: A Physical Mechanism for Cytotoxicity
Creators: name: Woodward, Daniel
name: Bell, Dylan
name: Tipton, David
name: Durrance, Samuel
name: Cole, Lisa
name: Li, Bin
name: Xu, Shaohua
Publisher: name: Columbia University
Year: 2014
Subjects: Nervous system--Degeneration
Cell-mediated cytotoxicity
Neurofibrils
Amyloid
Medicine

description: Amyloid fibers are associated with disease but have little chemical reactivity. We investigated the formation and structure of amyloids to identify potential mechanisms for their pathogenic effects. We incubated lysozyme 20 mg/ml at 55C and pH 2.5 in a glycine-HCl buffer and prepared slides on mica substrates for examination by atomic force microscopy. Structures observed early in the aggregation process included monomers, small colloidal aggregates, and amyloid fibers. Amyloid fibers were observed to further self-assemble by two mechanisms. Two or more fibers may merge together laterally to form a single fiber bundle, usually in the form of a helix. Alternatively, fibers may become bound at points where they cross, ultimately forming an apparently irreversible macromolecular network. As the fibers assemble into a continuous network, the colloidal suspension undergoes a transition from a Newtonian fluid into a viscoelastic gel. Addition of salt did not affect fiber formation but inhibits transition of fibers from linear to helical conformation, and accelerates gel formation. Based on our observations, we considered the effects of gel formation on biological transport. Analysis of network geometry indicates that amyloid gels will have negligible effects on diffusion of small molecules, but they prevent movement of colloidal-sized structures. Consequently gel formation within neurons could completely block movement of transport vesicles in neuronal processes. Forced convection of extracellular fluid is essential for the transport of nutrients and metabolic wastes in the brain. Amyloid gel in the extracellular space can essentially halt this convection because of its low permeability. These effects may provide a physical mechanism for the cytotoxicity of chemically inactive amyloid fibers in neurodegenerative disease.
Dinomys Peters 1873
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Dinomyidae
Dinomys

description: Dinomys Peters, 1873. Monatsb. Preuss. Akad. Wiss. Berlin, p. 551. ISIS NUMBER: 5301410021001000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 575, DOI: 10.5281/zenodo.7353039
Lack of Serologic Evidence to Link IgA Nephropathy with Celiac Disease or Immune Reactivity to Gluten
Creators: name: Moeller, Sina
name: Canetta, Pietro A.
name: Taylor, Annette K.
name: Arguelles-Grande, Carolina
name: Snyder, Holly
name: Green, Peter H. R.
name: Kiryluk, Krzysztof
name: Alaedini, Armin
Publisher: name: Columbia University
Year: 2014
Subjects: Kidneys--Diseases
Gluten
Celiac disease
Immune response
IgA glomerulonephritis
Medicine

description: IgA nephropathy is the most common form of primary glomerulonephritis worldwide. Mucosal infections and food antigens, including wheat gluten, have been proposed as potential contributing environmental factors. Increased immune reactivity to gluten and/or association with celiac disease, an autoimmune disorder triggered by ingestion of gluten, have been reported in IgA nephropathy. However, studies are inconsistent about this association. We aimed to evaluate the proposed link between IgA nephropathy and celiac disease or immune reactivity to gluten by conducting a comprehensive analysis of associated serologic markers in cohorts of well-characterized patients and controls. Study participants included patients with biopsy-proven IgA nephropathy (n = 99), unaffected controls of similar age, gender, and race (n = 96), and patients with biopsy-proven celiac disease (n = 30). All serum specimens were tested for IgG and IgA antibodies to native gliadin and deamidated gliadin, as well as IgA antibody to transglutaminase 2 (TG2). Anti-TG2 antibody-positive nephropathy patients and unaffected controls were subsequently tested for IgA anti-endomysial antibody and genotyped for celiac disease-associated HLA-DQ2 and -DQ8 alleles. In comparison to unaffected controls, there was not a statistically significant increase in IgA or IgG antibody reactivity to gliadin in individuals with IgA nephropathy. In addition, the levels of celiac disease-specific serologic markers, i.e., antibodies to deamidated gliadin and TG2, did not differ between IgA nephropathy patients and unaffected controls. Results of the additional anti-endomysial antibody testing and HLA genotyping were corroborative. The data from this case-control study do not reveal any evidence to suggest a significant role for celiac disease or immune reactivity to gluten in IgA nephropathy.
British Columbia Legislative Assembly sessional clipping book (1892-03)
Creators: name: :Unav
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Law
valueUri: http://id.worldcat.org/fast/993678
subject: FOS: Law
subject: British Columbia. Legislative Assembly
valueUri: http://id.worldcat.org/fast/600765
subject: Politics and government
valueUri: http://id.worldcat.org/fast/1919741

description: These Sessional Clippings books cover the period 1891 to 1972, and include newspaper accounts written by various legislative reporters who covered debates occurring in the British Columbia Legislative Assembly. Transcripts of debates of the Legislative Assembly (Hansard) were not published in B.C. until 1970; hence these "Sessional Clipping Books" augment the "Journals", the record of daily proceedings of the Legislative Assembly. Selected clippings from various newspapers including the Vancouver Sun, the Vancouver Province, the Colonist, and the Times newspapers, relating to the newspaper reports concerning activities of the Legislature. The original sessional clippings books comprise 351 ledger size print volumes, held at the Legislative Library in Victoria BC. The print volumes were microfilmed onto 26 reels in 1977 under a Tri University Libraries (TRIUL) project by Precision Micrographic Services (Vancouver, B.C.), with the permission of the Legislative Library, Victoria, British Columbia. This digital collection was created by scanning the 26 microfilm reels.
Particle acceleration in sub-cycle optical cells
Creators: name: Terranova, F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: High Energy Physics - Experiment (hep-ex)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: A single laser pulse with spot size smaller than half its wavelength ($w_0 < λ/2$) can provide a net energy gain to ultra-relativistic particles. In this paper, we discuss the properties of an optical cell consisting of $N$ sub-cycle pulses that propagate in the direction perpendicular to the electron motion. We show that the energy gain produced by the cell is proportional to $N$ and it is sizable even for $\mathcal{O}(1\mathrm{~TW})$ pulses.
description: 13 pages, 7 figures. Version to appear in PRSTAB
Idyllen; 1756 [erschienen] 1761
Creators: name: Gessner, Salomon
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2015

description: Erscheinungsjahr auf dem Kupfertitelbl.: 1756. - Nebentitel mit Erscheinungsjahr: MDCCLXI. - Verf. ermittelt
Sub-Nyquist Sampling for Power Spectrum Sensing in Cognitive Radios: A Unified Approach
Creators: name: Cohen, Deborah
name: Eldar, Yonina C.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In light of the ever-increasing demand for new spectral bands and the underutilization of those already allocated, the concept of Cognitive Radio (CR) has emerged. Opportunistic users could exploit temporarily vacant bands after detecting the absence of activity of their owners. One of the crucial tasks in the CR cycle is therefore spectrum sensing and detection which has to be precise and efficient. Yet, CRs typically deal with wideband signals whose Nyquist rates are very high. In this paper, we propose to reconstruct the power spectrum of such signals from sub-Nyquist samples, rather than the signal itself as done in previous work, in order to perform detection. We consider both sparse and non sparse signals as well as blind and non blind detection in the sparse case. For each one of those scenarii, we derive the minimal sampling rate allowing perfect reconstruction of the signal's power spectrum in a noise-free environment and provide power spectrum recovery techniques that achieve those rates. The analysis is performed for two different signal models considered in the literature, which we refer to as the analog and digital models, and shows that both lead to similar results. Simulations demonstrate power spectrum recovery at the minimal rate in noise-free settings and show the impact of several parameters on the detector performance, including signal-to-noise ratio (SNR), sensing time and sampling rate.
description: 13 pages
Two-dimensional von Neumann--Wigner potentials with a multiple positive eigenvalue
Creators: name: Novikov, R. G.
name: Taimanov, I. A.
name: Tsarev, S. P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: By the Moutard transformation method we construct two-dimensional Schrodinger operators with real smooth potential decaying at infinity and with a multiple positive eigenvalue. These potentials are rational functions of spatial variables and their sines and cosines.
description: 4 pages
Influenza Forecasting in Human Populations: A Scoping Review
Creators: name: Chretien, Jean-Paul
name: George, Dylan
name: Shaman, Jeffrey L.
name: Chitale, Rohit A.
name: McKenzie, F. Ellis
Publisher: name: Columbia University
Year: 2014
Subjects: Influenza--Epidemiology
Epidemics--Forecasting
Communicable diseases--Epidemiology
Influenza
Public health
Epidemiology

description: Forecasts of influenza activity in human populations could help guide key preparedness tasks. We conducted a scoping review to characterize these methodological approaches and identify research gaps. Adapting the PRISMA methodology for systematic reviews, we searched PubMed, CINAHL, Project Euclid, and Cochrane Database of Systematic Reviews for publications in English since January 1, 2000 using the terms “influenza AND (forecast* OR predict*)”, excluding studies that did not validate forecasts against independent data or incorporate influenza-related surveillance data from the season or pandemic for which the forecasts were applied. We included 35 publications describing population-based (N = 27), medical facility-based (N = 4), and regional or global pandemic spread (N = 4) forecasts. They included areas of North America (N = 15), Europe (N = 14), and/or Asia-Pacific region (N = 4), or had global scope (N = 3). Forecasting models were statistical (N = 18) or epidemiological (N = 17). Five studies used data assimilation methods to update forecasts with new surveillance data. Models used virological (N = 14), syndromic (N = 13), meteorological (N = 6), internet search query (N = 4), and/or other surveillance data as inputs. Forecasting outcomes and validation metrics varied widely. Two studies compared distinct modeling approaches using common data, 2 assessed model calibration, and 1 systematically incorporated expert input. Of the 17 studies using epidemiological models, 8 included sensitivity analysis. This review suggests need for use of good practices in influenza forecasting (e.g., sensitivity analysis); direct comparisons of diverse approaches; assessment of model calibration; integration of subjective expert input; operational research in pilot, real-world applications; and improved mutual understanding among modelers and public health officials.
Notions of Monad Strength
Creators: name: Mulry, Philip
Publisher: name: arXiv
Year: 2013
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Over the past two decades the notion of a strong monad has found wide applicability in computing. Arising out of a need to interpret products in computational and semantic settings, different approaches to this concept have arisen. In this paper we introduce and investigate the connections between these approaches and also relate the results to monad composition. We also introduce new methods for checking and using the required laws associated with such compositions, as well as provide examples illustrating problems and issues that arise.
description: In Proceedings Festschrift for Dave Schmidt, arXiv:1309.4557
British Columbia Legislative Assembly sessional clipping book (1892-04)
Creators: name: :Unav
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Politics and government
valueUri: http://id.worldcat.org/fast/1919741
subject: British Columbia. Legislative Assembly
valueUri: http://id.worldcat.org/fast/600765
subject: Law
valueUri: http://id.worldcat.org/fast/993678
subject: FOS: Law

description: These Sessional Clippings books cover the period 1891 to 1972, and include newspaper accounts written by various legislative reporters who covered debates occurring in the British Columbia Legislative Assembly. Transcripts of debates of the Legislative Assembly (Hansard) were not published in B.C. until 1970; hence these "Sessional Clipping Books" augment the "Journals", the record of daily proceedings of the Legislative Assembly. Selected clippings from various newspapers including the Vancouver Sun, the Vancouver Province, the Colonist, and the Times newspapers, relating to the newspaper reports concerning activities of the Legislature. The original sessional clippings books comprise 351 ledger size print volumes, held at the Legislative Library in Victoria BC. The print volumes were microfilmed onto 26 reels in 1977 under a Tri University Libraries (TRIUL) project by Precision Micrographic Services (Vancouver, B.C.), with the permission of the Legislative Library, Victoria, British Columbia. This digital collection was created by scanning the 26 microfilm reels.