cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Reducing computational complexity of convolutional neural networks through filter pruning
Creators: name: Singh, Arshdeep
name: Plumbley, Mark D.
Publisher: name: Zenodo
Year: 2022
Subjects: CNN, machine learning, pruning, audio classification

description: Poster presentation at "Exploring New Possibilities" 2022 Doctoral College Conference at University of Surrey, UK. Team Members: Dr Emily Corrigan-Kavanagh, Dr. Helen Cooper, Prof Mark D. Plumbley. Abstract: Convolutional neural networks (CNNs) have performed state-of-the-art in many real-life applications, including image and audio classification. However, the large size and the computational complexity of CNNs is a bottleneck to deploy them on hardware, particularly on resource-constrained devices such as smartphones. Moreover, when many intelligent devices are connected and communicating, the computation speed should be faster to act in real-time and make every connected device aware of the situation without any delay. Therefore, reducing the size and speed-up in computations of CNNs during inference is an essential task for efficiency. Apart from obtaining efficient CNNs during inference, reducing computations in CNNs may reduce CO2 emission during their training stage. Typically, training CNNs for more time generates more CO2, e.g. running GTX 1080 Ti hardware for two days generates CO2 equal to 5.18 kg, equivalent to driving an average car for 20Km. Therefore, it is crucial to reduce CNNs computational complexity for sustainable solutions. The literature shows that CNNs require a large number of parameters to solve complex non-linear tasks. However, once the CNNs are trained, there may be redundancy in their parameters, and it is possible to obtain a sub-network from the original network that gives similar performance as that of the original network at a reduced number of parameters. One of the methods to obtain sub-network is through filter pruning, where the filters or parameters learned in CNNs are explicitly removed from the original network based on their importance. This work aims to remove filters based on their similarity and assume that similar filters produce similar output, and hence, one of the filters can be removed. By removing similar filters, our proposed method achieves a 25% reduction in parameters and 27% speed-up in computations at marginal drop in accuracy compared to the original network.
description: This work was supported by Engineering and Physical Sciences Research Council (EPSRC) Grant EP/T019751/1 "AI for Sound"
Quantitative Hrtem Analysis Of Strain Assessment Along The Defect Cores In Cryo-Rolled Cp Ti
Creators: name: Ghosh, Chanchal
name: Dasgupta, Arup
name: Pragna Bhaskar
name: R. Mythili
name: S. Raju
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Post-Synthetic Modification Of A Metal-Organic Framework Fordualnaked-Eye Fluorogenic Detectionin Aqueous Medium
Creators: name: Dalapati, Rana
name: Biswas, Shyam
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
FACTORES ASOCIADOS A DEFECTOS CONGÉNITOS
Creators: name: Vasco-Toapanta, Cristhian
name: Salas Escobar, Pablo Andrés
name: Espinoza Serrano, Alisson Stefany
name: Guanoluisa Vasco, Alisson Mayerly
Publisher: name: Zenodo-HGOIA
Year: 2024
Subjects: Recién nacido
Factores de riesgo perinatales
Defectos congénitos

description: El riesgo de anomalías congénitas es universal y tienen un impacto en la mortalidad y morbilidad de los individuos afectados. Los tudios epidemiológicos son esenciales para mejorar el entendimiento de los factores de riesgo asociados.

OBJETIVO:

Determinar los factores de riesgo asociados a anomalías congénitas en recién nacidos ingresados en el  Hospital Gineco-Obstétrico Isidro Ayora de Quito.
РАЗРАБОТКА МЕТОДОВ КОНТРОЛЯ КАЧЕСТВА  СУХОГО ЭКСТРАКТА ИЗ ЛИСТЬЕВ  HIPPOPHAE RHAMNOIDES L
Creators: name: Тошбобоева, Л.
name: Мухитдинова, К.Ш.
Publisher: name: Zenodo
Year: 2024

description: Растение облепихи издревле применяются для лечения многих болезней. В медицине в большей степени применяется мало облепихи. Но в последнее время научные деятелями России и других зарубежных стран проводятся исследования листьев облепихи.   Листья облепихи богаты витаминами и имеют не малое место в медицине, а так же в фармацевтике. Листья кустарника содержат гипорамин, который обладает противовирусной активностью, поэтому из него делают таблетки для лечения гриппа и простуды. Гипорамин обладает высокой противовирусной активностью в отношении различных штаммов вирусов гриппа А и В, аденовирусов, парамиксовирусов, вирусов простого герпеса, опоясывающего лишай, цитомегаловирусов (ЦМВ), респираторно-синцитиального вируса (PC-вируса), вирусов иммунодефицита.
Guaranteed in-control control chart performance with cautious parameter learning
Creators: name: Capizzi, Giovanna
name: Masarotto, Guido
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Parameter estimation has a large impact on control chart performance. Recently, widened control limits have been suggested to guarantee an acceptable in-control behavior. However, the consequence is a reduced ability to detect a real change in the process. In order to overcome this undesired effect, we explore an alternative design based on a delayed updating of parameter estimates. We consider an application to the Shewhart X, EWMA, and CUSUM control charts for the process mean. This approach is simple to implement, reduces the variation of the in-control average run lengths, and significantly improves the out-of-control performance.
The impact of therapy dogs on nursing staff mood in the emergency department a pilot study
Creators: name: Santos, Jessica
Publisher: name: No Publisher Supplied
Year: 2020

description: Purpose of Project: The purpose of this project is to quantify the reduction in negative mood in emergency department registered nurses and to improve satisfaction in their positions with the implementation of pet therapy. Methodology: A quasi-experimental design with pre- and post-test questionnaire using the Abbreviated Profile of Mood States (POMS) before and after interacting with a therapy dog.Results: A total of 40 participants completed the pre- and post-test questionnaire, as well as the short demographic questionnaire. Using the Wilcoxon Sums Rank Test, there were statistically significant findings (p<0.0005) for impact on the RNs mood after interacting with the therapy dog.Implications for Practice: Studies on pet therapy have demonstrated the positive effects of pet therapy with patients. However, there are limited studies on pet therapy as an intervention for healthcare providers. Incorporating pet therapy to RNs and other staff members is a cost-effective method that can improve their mood and may help retain staff.
A Reconnaissance Inventory of Air Combat Command Cold War Material Culture, Little Rock Air Force Base: A Baseline Inventory of Cold War Material Culture
Creators: name: Lowe, James A.
name: Evaskovich, John A.
name: Roxlau, Katherine J.
Publisher: name: Mariah Associates, Inc.
Year: 1995
Subjects: subject: Little Rock Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/80897/little-rock-air-force-base
subject: Little Rock, Arkansas
valueUri: https://core.tdar.org/browse/geographic-keyword/76773/little-rock-arkansas
subject: Cold War Era
valueUri: https://core.tdar.org/browse/temporal-keyword/5551/cold-war-era
subject: Cold War
valueUri: https://core.tdar.org/browse/temporal-keyword/7288/cold-war
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Military Structure
valueUri: https://core.tdar.org/browse/site-type/322/military-structure
subject: Bomber Alert Facility
valueUri: https://core.tdar.org/browse/site-type/4066/bomber-alert-facility
subject: Non-Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/309/non-domestic-structures
subject: Personnel Interviews
valueUri: https://core.tdar.org/browse/other-keyword/166607/personnel-interviews
subject: Base Newspaper Collection
valueUri: https://core.tdar.org/browse/other-keyword/166608/base-newspaper-collection

description: Mariah Associates, Inc. conducted a cultural resource inventory at Little Rock Air Force Base, Arkansas, between November 14 and 17, 1994 to identify extant Cold War resources important to the base, its history, and its Cold War mission. A variety of repositories were inventoried on base: the Wing History Office, Public Affairs Office, Civil Engineering Office and Drafting Department, Real Estate Office, and Environmental Office. Informal interviews were conducted with personnel long affiliated with the base to better understand the relationship of specific base properties to the Cold War era. A photographic reconnaissance of the base was conducted to document Cold War properties as well as representative architecture on the base. Four resources were selected for documentation and evaluation due to their importance within the base Cold War context. The Bomber Alert Facility represents the United States Air Force alert posture and deterrence capabilities indicative of the Cold War era. Recommendations include further documentation, National Register of Historic Places eligibility, and stewardship. The Base Newspaper Collection, Documentary Collection, and Office Files illustrate the development of the base during the Cold War, describe historical base events, and provide information on specific base properties. Recommendations include further documentation, stewardship, and conservation for the two collections, and stewardship for the Office Files.
The pizza cathedral
Creators: name: Lewine, Lia
Publisher: name: No Publisher Supplied
Year: 2022

description: My unnamed protagonist learns that her dead mother kept an Instagram account for their Papillon, Frank (@FranklintheFluff). The narrator dropped out of her final semester at Columbia to deal with her mother’s death. The protagonist makes a goal of making Franklin Instagram famous as a way of coping with her mother’s death. Her landlord says if she cannot pay the rent, she will be evicted in a month. The narrator has almost no money in her bank account. All of her mother’s accounts have been frozen. Against the odds, @FranklintheFluff gets inundated with followers, likes, hearts, and brand deals. Instagram fame seems within reach. Just after getting enough sponsorship money to pay the rent, Franklin starts refusing to eat food. The more the narrator pressures him to pose for photos, the more sick that he gets. To help him, the narrator is forced to realize that she needs to be able to reach out to others. Through her experience with Frank’s illness and eventual death, the narrator is able to start dealing with her grief over her mother, as well as confront her romantic feelings towards her friend Ty.
Rietveld Structural Analysis Of New Bi-Based Piezoceramics With Morphotropic Phase Boundary
Creators: name: Akhilesh Kumar Sing
name: Rishikesh Pandey
name: Upadhyay, Ashutosh
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Erklärvideos im Biologieunterricht, vom informellen zum formalen Lernwerkzeug?! –
Creators: name: Bruckermann, Till
name: Mahler, Daniela
name: Meier, Monique
Publisher: name: Zeitschrift für Didaktik der Biologie (ZDB) - Biologie Lehren und Lernen
Year: 2022

description: Erklärvideos können das fachliche Lernen bereichern, vorausgesetzt, sie werden didaktisch begründet ausgewählt oder produziert sowie eingesetzt. Beispielsweise unterstützen sie die mentale Vorstellungskraft und ermöglichen Lernenden eine gute Performanz sowie Sicherheit beim Experimentieren. Trotz ihrer Potenziale liegen bisher fast ausschließlich empirische Befunde aus der Instruktionspsychologie und nur wenige Untersuchungen vor, die sich aus einer fachdidaktischen Perspektive mit Erklärvideos auseinandersetzen. Angesichts der wachsenden Bedeutung von Erklärvideos beim informellen Lernen werden drei Thesen zum formalen Lernen im Biologieunterricht diskutiert, welche die Verfügbarkeit und Qualität von Erklärvideos, lernförderliche Einsatzszenarien und die professionelle Wissensbasis über Qualität und Einsatz von Erklärvideos betreffen. Ziel des Beitrags ist, die Diskussion zu den Thesen zusammenzufassen und in die Literatur einzuordnen. Es wird erläutert, anhand welcher Kriterien sich die Qualität von Erklärvideos einschätzen lässt, wie ein zielführender und didaktisch begründeter Einsatz von Erklärvideos aussehen kann und welches Wissen Lehrkräfte benötigen, um qualitativ hochwertige Videos zu erkennen und diese didaktisch begründet einzusetzen. Die in der Diskussion aufgezeigten Wirkungsbereiche von Erklärvideos verdeutlichen, wo zukünftige Forschung ansetzen kann, um die Unterrichtspraxis in der Biologie durch empirische Befunde zum lernförderlichen Videoeinsatz weiterzuentwickeln.
description: Zeitschrift für Didaktik der Biologie (ZDB) - Biologie Lehren und Lernen, Bd. 26 (2022)
D-JRA3.2 Distributed Simulation Platform
Creators: name: Subramaniam Rajkumar, Vetrivel
name: Pham, Minh Cong
name: Tran, Quoc Tuan
name: Gehrke, Oliver
name: Arhum, Mohammad
name: Acosta, Andres
Publisher: name: The ERIGrid 2.0 Consortium
Year: 2024
Subjects: Configuration Management
Automation
Virtual Access
Joint Research Infrastructure
Data Exchange
Deliverable
European Union (EU)
H2020
Project
ERIGrid 2.0
GA 870620

description: This report summaries the work undertaken in ERIGrid 2.0 towards improved and extended Research Infrastructure (RI) services (i.e., integration, coupling, and automation). More specifically, the following work is covered:

Development of a Configuration Management (CM) tool to greatly improve the automation and reproducibility of multi-RI experiments. This tool plays a pivotal role in managing and maintaining experiment configurations, ensuring consistency and reliability in the experimental research process.

Creation of automation sequences and scripts designed to automate the configuration and execution of simulation-based experiments. These scripts streamline the process of setting up and running simulations, thereby improving the efficiency and accuracy of workflows.

 Deployment of Simulation-as-a-Service (SaaS) for virtual laboratory access. This facilitates convenient and scalable virtual access to laboratory infrastructures, thereby enhancing accessibility.

Together, these implementations underscore the advancement in the capabilities of RIs by incorporating automation, reproducibility, and enhanced access through innovative virtual services.
title: Guidance for Registering DataCite DOIs for Awards
Creators: name: Chen, Xiaoli
Publisher: name: DataCite
publisherIdentifier: https://ror.org/04wxnsj81
publisherIdentifierScheme: ROR
Year: 2024

description: DataCite is a global community of research organizations with a common purpose. As part of this effort and aligned with our multi-year strategy, we launched a pilot to help our community track awards and related outputs. During the pilot, we registered award DOIs, coordinated on common challenges, established clear community guidelines, and will now work to improve our existing services to better support use cases. This work is integral to our vision.

We are pleased to share that as we wind down our successful award ID pilot program, we have confirmed its strategic alignment and positive impact within our community. With this validation, we are excited to extend award ID services more broadly, enhancing our commitment to community engagement and recognition.
Implementing multimodal smoking cessation interventions in adult primary care
Creators: name: Silva-Esquivel, Maria
Publisher: name: No Publisher Supplied
Year: 2020

description: Purpose of Project: The purpose of this study was to implement multimodal smoking cessation interventions in a primary care setting.Methodology: This DNP project used a mixed methods participatory inside action research approach, to implement multimodal smoking cessation interventions using the 5A’s and the 5R’ s of smoking cessation, in a primary care setting. The DNP student investigator organized learning circle meetings to educate the healthcare team, to develop the implementation and adaptation of these interventions, and to leave a sustainable workflow for smoking cessation interventions for the practice to use. Chart reviews were performed to assess for adherence to interventions and force field analysis of the potency and amenability to change of the CFIR constructs.Results: The results showed multiple barriers, facilitators, and unexpected findings, which guided the adaptation of workflows and the implementation plan. Evaluation of the data showed that adherence to asking about smoking status was 100%, and the rate of assisting patients in quitting smoking was 72%. The rest of the interventions had much lower adherence rates due to multiple barriers. The increase in potency and amenability to change of the CFIR constructs were in direct correlation to the adaptation of interventions to the practice. These results cannot be generalized, but they indicate that participatory inside action research had partial success in implementing smoking cessation interventions in a primary care setting.Implications for Practice: Progress towards the patient’s quality of care and safety was obtained after the implementation of smoking cessation in the primary care office, but further work needs to be done to increase adherence. Further education is needed to be provided for the primary care providers to acquire a high level of skill set to apply interventions that are more time consuming, such as motivational interviewing.
Marine sediment characterization through echo sounder measurement analysis
Creators: name: Shearer, Lucas Ryan
name: 0000-0002-7944-1831
Publisher: name: The University of Texas at Austin
Year: 2020
Subjects: Sediment
Characterization
Underwater
Acoustics
Echo
Sounding

description: Echo sounder measurements were used to quantify bottom loss from muddy seafloors during the Seabed Characterization Experiment (SBCE), and at the Dauphin Island Sea Lab (DISL) in 2017. Data were processed with a combination of matched and bandpass filters to obtain metrics which describe the magnitude and shape of the bottom reflection return. While the SBCE measurements were gathered at normal incidence, many of the DISL measurements were taken at significantly larger incident angles. Those data collected at near-normal incidence were used to estimate geophysical properties through the application of existing empirical regression equations. Data collected at oblique incidence were used to determine sediment sound speed and density ratios through a two-parameter inversion, using the flat interface Rayleigh reflection formula. The estimated values were compared to in-situ and laboratory ground truth measurements. The accuracy of each approach and the causes of bottom loss variability (bioturbation, gradients, inhomogeneities, etc.) are discussed.
Autism in Lagos: a case study of special education transfer
Creators: name: Chiemelu, Obianuju
Publisher: name: No Publisher Supplied
Year: 2022

description: This research examined special education transfer as it pertains to students with Autism Spectrum Disorder (ASD), using a case study of the Lagos Speech Center (LSC), a special education program located in Lagos, Nigeria. The study also examined LSC’s advocacy and awareness efforts in relation to disability rights in Nigeria. David Philip’s theory of policy attraction and David Johnson’s model on postcolonial educational borrowing trajectories were woven together to examine the special education transfer process. This study also employed Eyerman and Jamison’s cognitive approach to social movement theory to explore the advocacy and awareness efforts of the program. Document and literature reviews, semi-structured interviews, and non-participatory observations were utilized for data collection.Findings show that the biomedical interpretation of ASD and disability rights ideologies plays a significant role in reshaping disability culture in Lagos. However, acceptance of the biomedical interpretation and the way in which LSC’s educational program is utilized vary. While some families accepted ASD as a neurodevelopmental disability, others continued to hold indigenous beliefs about the spiritual nature of the phenomenon. Families’ views concerning the cause of ASD impacted responses to program practices and interventions. At the same time, the severity of ASD manifestations in students influenced the duration and intensity of the program’s application of interventions. This research also found that colonial history guided the choice of Western knowledge concerning ASD, through access to nations with shared colonial histories, resulting in a preference for educational products marketed by these nations. LSC’s advocacy and awareness efforts centered on knowledge dissemination concerning the biomedical origin of ASD, the inclusion of individuals with ASD into society, and the benefits of specialized services. These knowledge interests wholly aligned with the special education transfer process, supporting the premise that special education must coextend with a social movement for disability rights.Results of this study suggest the success of LSC is a consequence of the willingness and desire, within the local context, for a cultural shift away from an exclusionary response to ASD. Results also highlight the need for localized research on ASD that is grounded on indigenous cultural perspective.
Perinatal mental health: how nordic data sources have contributed to existing evidence and future avenues to explore
Creators: name: Karalexi, Maria A.
name: Eberhard-Gran, Malin
name: Valdimarsdóttir, Unnur Anna
name: Karlsson, Hasse
name: Munk-Olsen, Trine
name: Skalkidou, Alkistis
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Perinatal mental health disorders affect a significant number of women with debilitating and potentially life-threatening consequences. Researchers in Nordic countries have access to high quality, population-based data sources and the possibility to link data, and are thus uniquely positioned to fill current evidence gaps. We aimed to review how Nordic studies have contributed to existing evidence on perinatal mental health. We summarized examples of published evidence on perinatal mental health derived from large population-based longitudinal and register-based data from Denmark, Finland, Iceland, Norway and Sweden. Nordic datasets, such as the Danish National Birth Cohort, the FinnBrain Birth Cohort Study, the Icelandic SAGA cohort, the Norwegian MoBa and ABC studies, as well as the Swedish BASIC and Mom2B studies facilitate the study of prevalence of perinatal mental disorders, and further provide opportunity to prospectively test etiological hypotheses, yielding comprehensive suggestions about the underlying causal mechanisms. The large sample size, extensive follow-up, multiple measurement points, large geographic coverage, biological sampling and the possibility to link data to national registries renders them unique. The use of novel approaches, such as the digital phenotyping data in the novel application-based Mom2B cohort recording even voice qualities and digital phenotyping, or the Danish study design paralleling a natural experiment are considered strengths of such research. Nordic data sources have contributed substantially to the existing evidence, and can guide future work focused on the study of background, genetic and environmental factors to ultimately define vulnerable groups at risk for psychiatric disorders following childbirth.
An inducible model for unraveling the effects of advanced glycation end-product accumulation in aging connective tissues
Creators: name: Gouldin, Austin G.
name: Brown, M. Ethan
name: Puetzer, Jennifer L.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 60506 Virology

description: In connective tissues there is a clear link between increasing age and degeneration. Advanced glycation end-products (AGEs) are believed to play a central role. AGEs are sugar-induced non-enzymatic crosslinks which accumulate in collagen with age and diabetes, altering tissue mechanics and cellular function. Despite ample correlative evidence linking collagen glycation to tissue degeneration, little is known how AGEs impact cell-matrix interactions, limiting therapeutic options. One reason for this limited understanding is that AGEs are typically induced using high concentrations of ribose which decrease cell viability, making it impossible to investigate cell-matrix interactions. The objective of this study was to develop a system to trigger AGE accumulation while maintaining cell viability. Using cell-seeded high density collagen gels, we investigated the effect of two systems for AGE induction, ribose at low concentrations (30, 100, and 200 mM) over 15 days of culture and riboflavin (0.25 and 0.75 mM) induced with blue light for 40 seconds (riboflavin-465 nm). We found ribose and riboflavin-465 nm treatment produces fluorescent AGE quantities which match and/or exceed human fluorescent AGE levels for various tissues, ages, and diseases, without affecting cell viability or metabolism. Interestingly, a 40 second treatment of riboflavin-465 nm produced similar levels of fluorescent AGEs as 3 days of 100 mM ribose treatment. Riboflavin-465 nm is a promising method to trigger AGEs on demand in vivo or in vitro without impacting cell viability and offers potential for unraveling the mechanism of AGEs in age and diabetes related tissue damage.
ISOLATION OF CURCUMIN EXTRACT FROM CURCUMA LONGA
Creators: name: Rakhimova, M.SH.
name: Azizov, SH.I.
Publisher: name: Zenodo
Year: 2024

description: Curcumin, a polyphenol of yellow crystals with that gives turmeric its yellow color, it is extracted from the rhizome of turmeric. It belongs to the perennial herb named Curcuma longa L.
Pre-trained language models to curate oligogenic data
Creators: name: Nachtegael, Charlotte
name: De Stefani, Jacopo
name: Cnudde, Anthony
name: Lenaerts, Tom
Publisher: name: F1000 Research Limited
Year: 2024

description: Work presented for the workshop on Text mining services to support scalable curation.

By pre-annotating 85 full-text articles containing the relevant oligogenic relations from the Oligogenic Diseases Database (OLIDA) with PubTator, text fragments featuring potential digenic variant combinations, i.e. gene–variant–gene–variant, were extracted. The resulting fragments of texts were annotated with ALAMBIC, an AL-based annotation platform. The resulting dataset, called DUVEL, is used to fine-tune four state-of-the-art biomedical language models: BiomedBERT, BiomedBERT-large, BioLinkBERT and BioM-BERT. More than 500 000 text fragments were considered for annotation, finally resulting in a dataset with 8442 fragments, 794 of them being positive instances, covering 95% of the original annotated articles. When applied to gene–variant pair detection, BiomedBERT-large achieves the highest F1 score (0.84) after fine-tuning, demonstrating significant improvement compared to the non-fine-tuned model, underlining the relevance of the DUVEL dataset. DUVEL provides a unique biomedical corpus focusing on 4-ary relations between two genes and two variants. It is made freely available for research on GitHub and Hugging Face.
Treatment and Visual Outcomes in Pediatric Patients with Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy: A Cohort Study
Creators: name: Maccora, Ilaria
name: Ebert, Jared J.
name: Schulert, Grant S.
name: Quinlan-Waters, Megan
name: Duell, Alexandra
name: Huggins, Jennifer L.
name: Sapp, Cameron C.
name: Nguyen, Tiffany
name: Srivastava, Sunil K.
name: Sood, Arjun B.
name: Angeles-Han, Sheila T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Autosomal dominant neovascular inflammatory vitreoretinopathy (NIV), formerly called “ADNIV,” is a rare autoinflammatory condition mainly of adulthood caused by mutations in calcium-activated calpain-5 protease (CAPN5). Our aim is to report the treatment and visual outcomes of children newly diagnosed with NIV after systemic treatment. We reviewed charts of patients ≤18 years old with CAPN5 gene mutation, ocular findings consistent with NIV, and treated with systemic immunosuppression for a minimum of 6 months. Treatment response was based on ophthalmic examination, ultra-widefield fluorescein-angiography (UWFFA), and optical coherence tomography (OCT). Eight children (16 eyes) were diagnosed with NIV at a median age of 14 (Range [R] 9–16) years, with a median follow-up of 18 months (R6–20). At diagnosis, one patient had impaired visual acuity (VA > 0.4), eight had vascular leakage, two had neovascularization, and three had macular edema. All responded to oral or local glucocorticoids but was not sustained. Systemic immunosuppression was started in seven patients with methotrexate and infliximab after a median time from diagnosis of 1.5 months (R0.5–2) and 3.2 months (R2.5–3.1), respectively. Infliximab was discontinued in all after a median time of 7 months (R3.5–10) for ineffectiveness, and 5/7 switched to tocilizumab and 1 to adalimumab. Five failed to respond (4 tocilizumab, 1 adalimumab) and one had a minimal response to tocilizumab We report on the systemic treatment response of seven children with ADNIV treated with methotrexate, infliximab, and tocilizumab. None were able to control disease. Further studies are needed to understand long-term outcomes and the utility of systemic immunosuppression.
Synthesis And Characterization Of Vanadium Pentoxide For Methane Gas Sensing
Creators: name: P.R Reshma
name: Prasad, Arun K
name: Arindam Das
name: G.Mangamma
name: S.Dhara
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Evaluation of fiber compositions, strength indicators, and disintegration patterns of flushable sanitary products in relevance to what is flushable
Creators: name: Eren, Beytullah
name: Nigdelioglu, Mustafa
name: Karadagli, Fatih
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Sanitary products (SPs) such as toilet paper and moist wipes are marketed as flushable products (FPs). SP manufacturers, wastewater authorities, and governmental agencies describe FPs in their own terms, and cause confusion about what is safe to flush with respect to sewer operations. To identify sewer-safe FPs, 11 toilet paper (TP) and 39 flushable wipe (FW) samples that were collected from around the world were examined to assess critical links between their fiber compositions, strength indicators, and disintegration performance. The findings illustrate that products that are made of primarily wood-pulp fibers have low strength, disintegrate rapidly, and are safe flushables. In contrast, products that contain strong and synthetic fibers (e.g. polyester) exhibit high strength, disintegrate slowly, and pose significant risk of accumulation in sewer systems. Suggestions are offered for product improvement and for long-term sustainability of FPs and wastewater infrastructures.
Large Negative Magnetoresistance And Thermal Properties Of Ni50-Xmn37+Xsn13(X = 0, 1, 2, 3) Heusler Alloys
Creators: name: S.Esakki Muthu
name: S. Arumugam
name: P. Sivaprakash
name: M.Manivel Raja
name: N.V. Ramarao
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Residues of endocrine-disrupting PCBs in drinking water - influence of water and wastewater treatment in Szczecin (Poland)
Creators: name: Cybulski, Jacek
name: Witczak, Agata
name: Pokorska-Niewiada, Kamila
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Drinking water is subjected to several stages of treatment, but it can still retain residues of endocrine-disrupting compounds. These include polychlorinated biphenyls (PCBs). The aim of this study was to assess the efficiency of water and wastewater treatment processes on reducing residues of endocrine-disrupting PCB congeners in drinking water and treated wastewater. The analyses were performed with liquid–liquid extraction and gas chromatography coupled with mass spectrometry. PCB congener residues were found in 18% of the drinking water samples. The water treatment process reduced the content of these compounds within a wide range of 4% to 100%. Estimates of consumer exposure to these compounds from drinking water consumption accounted for as much as 30% of the tolerable weekly intake (TWI). The wastewater treatment process reduced the concentration of PCB congeners by 38–98%, with trace contents in the treated wastewater (from 0.02 · 10–6 to 6.21 · 10–6 mg/l).
Structural And Vibrational Studies On Co-Crystal: 5-Fluorouracil 4-Amino Benzoic Acid
Creators: name: S. Suresh Kumar
name: S. Athimoolam
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Unraveling the Spectrum of Uveitis: Insights from an Epidemiological Study in a National Referral Center in Northern Italy
Creators: name: Menean, Matteo
name: Scandale, Pierluigi
name: Apuzzo, Aurelio
name: Barresi, Costanza
name: Checchin, Lisa
name: L’Abbate, Gaia
name: Fantaguzzi, Federico
name: Rissotto, Federico
name: Servillo, Andrea
name: Cucuccio, Elena
name: Modorati, Giulio
name: Marchese, Alessandro
name: Bandello, Francesco
name: Cicinelli, Maria Vittoria
name: Miserocchi, Elisabetta
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Uveitis embraces a heterogeneous group of vision-threatening inflammatory conditions. Understanding uveitis epidemiology, etiology, and clinical findings is fundamental for a prompt diagnosis and optimal patient management. The aim of the study is to report the epidemiology of uveitis in a national referral center in Northern Italy and investigate the visual prognosis. This retrospective study was conducted at Uveitis Service (Ospedale San Raffaele) between June 2016 and May 2023. Demographic data, clinical characteristics, and etiological diagnoses of uveitis patients were collected, and visual prognosis was longitudinally explored. 1105 patients with uveitis were included in the study, while 47 patients presented neoplastic masquerade syndrome and have been excluded. The population had a slight majority of females (M/F ratio = 0.76), mean age was 47 years. 25% presented infectious uveitis, primarily due to herpetic etiology, toxoplasmosis, and tuberculosis. Non-infectious uveitis was the most prevalent diagnosis (38%), with sarcoidosis, HLA-B27-associated uveitis, and Fuch’s uveitis as prominent causes. Anatomically, anterior segment was most frequently involved (41%). Significant improvement in visual acuity was observed at follow-up, particularly in patients with infectious uveitis. Our study sheds light into the epidemiological landscape of uveitis in Northern Italy, reflecting changing patterns due to factors such as migration and changing sexual habits. In particular, higher percentages of syphilis have been observed, compared to other European reports. The distribution of non-infectious uveitis reflects other epidemiological European series. Higher percentages of neoplastic masquerade syndromes support the need of early recognition. Our findings offer precious insights for uveitis epidemiology and daily clinical practice.
Characterization Of Al-6061 Based Metal Matrix Composite Fabricated By Stir Casting Route And Modified By Friction Stir Processing (Fsp)
Creators: name: Sourabh, Kumar
name: Suhrit Mula
Publisher: name: Zenodo
Year: 2018

description: The talk presented at 29th Annual General Meeting Of Materials Research Society Of India And National Symposium On Advances In Functional And Exotic Materials.
Additional file 1 of The Pandemic Stressor Scale: factorial validity and reliability of a measure of stressors during a pandemic
Creators: name: Lotzin, Annett
name: Ketelsen, Ronja
name: Zrnic, Irina
name: Lueger-Schuster, Brigitte
name: Böttche, Maria
name: Schäfer, Ingo
Publisher: name: figshare
Year: 2022
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplements.
Improving advance care planning in primary care
Creators: name: Singh, Dashmeet
Publisher: name: No Publisher Supplied
Year: 2020

description: Purpose of Project: As the life spans of Americans are increasing so is the number of people who are living longer with multiple chronic comorbid conditions. End of life care can be protracted and very expensive. However, end of life treatment goals, articulated in advance care planning (ACP), can address these concerns. ACP is defined as the voluntary process in which patients discuss and communicate their future treatment and end-of-life preferences with their provider in case they lose their capacity to make decisions or communicate their wishes and preferences in the future. Primary care settings are ideal for the integration of ACP as part of routine care and health maintenance. However, a review of literature has shown that primary care patients do not routinely engage in ACP with their providers. As such, this project aimed to increase the number of ACP conversations that occur in a single primary care office and attempted to reduce provider associated barriers to ACP in the primary care setting.Methodology: A quality improvement project that measured the effectiveness of an ACP educational module presented to participants in a live setting. Pretest and posttest design was used to compare participant knowledge base and attitudes towards ACP before and after intervention. Data was analyzed using the McNemar test. Frequencies of the number of times the ACP billing code was used were compared in the 4-week period both before and after intervention.Results: This study resulted in a positive change in provider knowledge base and attitude towards ACP. Providers reported decreased apprehension in beginning ACP conversations with their patients as a result of the intervention. Additionally, the number of times ACP was billed for in the setting went from 0 pre-intervention to 336 in the post-intervention period. Moreover, a permanent integration of an ACP policy at the primary care center was put into effect as a result of the intervention.Implications for Practice: This study demonstrated the feasibility of integrating ACP in primary care, increasing revenue for primary care settings, improving patient autonomy in end of life healthcare decision-making, and increasing the overall quality of healthcare services rendered.
title: Feeding efficiency and aggression in juvenile Atlantic salmon, Salmo salar (L.) under alternative feeding regimes
Creators: name: Noble, Christopher
Publisher: name: University of Glasgow
Year: 2001
Subjects: subject: Aquatic sciences.

description: This thesis is a compilation of three long-term studies of on-demand feeding in Atlantic salmon parr and post-smolts in an aquacultural cage environment. The feeding rhythm studies are concerned with whether fish show a daily rhythm of appetite in cage culture. The feeding regime chapters evaluate the effect of an on-demand feeding regime upon growth performance and production when compared with existing fixed ration regimes. Two studies assess the impact of feeding regime upon social interactions around meal times, examining aggression and competition in relation to food presentation. My aim was to show how feeding systems that preferentially distribute feed in relation to changes in appetite could affect fish production and welfare in a cage rearing facility. The AKVAsmart AQ1 adaptive feeding system is the on-demand feeder used throughout this thesis. It is a system that has been designed principally for cage culture and can manage several feeding programs, depending upon farmers' requirements. Chapter 2 reports on the general configuration of the on-demand feeders for each of cage trials in this thesis, outlining the behavioural and production implications of the parameters chosen. Chapter 3 is split into two parts: 3a reports upon the feeding rhythms of Atlantic salmon post- smolts in sea cages; 3b examines the effect of an on-demand feeding regime upon growth performance and social interactions between conspecifics. Chapter 4 is divided into three sections: 4a provides information on feeding rhythms in freshwater production cages under ambient conditions from autumn until spring; 4b evaluates the effects of an on-demand feeding regime on growth performance and production of parr in comparison with an existing fixed ration regime; and 4c examines how a feeding regime can affect the prevalence of fin damage and behavioural interactions between conspecifics around meal times. The final experimental chapter was split into two segments: 5a investigated the feeding rhythms of cage held Atlantic salmon parr in production cages under an artificial photoperiod (as part of an accelerated smoltification strategy); 5b examines the effect of an on-demand feeding regime on growth and production in comparison with an in-house fixed ration regime. Chapter 6 reviews the main conclusions and findings of the previous chapters, outlining their implications for aquacultural feed management strategies. (Abstract shortened by ProQuest.).
Additional file 1 of Bacterial composition and colony structure of the lower respiratory tract in infants and children with recurrent wheezing: a case–control study
Creators: name: Yao, Jiawei
name: Ai, Tao
name: Xia, Wanmin
name: Fan, Yinghong
name: Xie, Cheng
name: Zhang, Lei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Table 1. Alpha diversity indices of all oropharyngeal samples. Fig. 1. Multiple rarefaction curves of the richness and Rank Abundance. Fig. 2 NMDS based on the Bray-Curtis distances at the OTU level at 97% identity. Fig. 3 All significantly different phyla and genera detected by LefSe.
Tear Cytokines as Predictive Biomarkers of Success in Contact Lens Discomfort Management
Creators: name: Calderón-García, Andrés Ángel
name: la Rosa, Alberto López-de
name: Valencia-Nieto, Laura
name: García-Vázquez, Carmen
name: Arroyo-del-Arroyo, Cristina
name: López-Miguel, Alberto
name: Blanco-Vázquez, Marta
name: Novo-Diez, Andrea
name: Fernández, Itziar
name: de Salamanca, Amalia Enríquez
name: González-García, María Jesús
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: To analyze changes in tear levels of inflammatory mediators in symptomatic contact lens (CL) wearers after refitting with daily disposable CLs and to identify potential biomarkers of success in CL discomfort (CLD) management. Symptomatic CL wearers (CLDEQ-8 ≥ 12) were refitted (V1) with daily disposable CLs (Delefilcon A). After one month (V2), participants were classified into the post-fitting non-symptomatic (CLDEQ <12) and symptomatic (CLDEQ ≥12) groups. At each visit, the participants were clinically evaluated, tears were collected, and 20 inflammatory mediators and substance P (SP) were measured using multiplex immunobead analysis and ELISA, respectively. The detection rates and concentrations were compared between visits and groups, and logistic regression models were performed. Forty-three subjects (32 women/11 men; mean age: 23.2 ± 4.9 years) were enrolled. The IL-1β and IL-9 detection rates were higher at V2 (p ≤ 0.044). The detection rates of IL-1β, IL-9, MIP-1α/CCL3, and MMP-9 at V1 (p ≤ 0.045) and IL-17A at V2 (p ≤ 0.014) were higher in the post-fitting symptomatic group. The tear IL-9 concentration was increased at V2 (p = 0.018). The tear concentrations of fractalkine/CX3CL1, IL-2, IL-6, IL-10, MCP-3/CCL7, MIP-1β, NGF, RANTES/CCL5, and TNF-α were higher in the post-fitting symptomatic group (p ≤ 0.044). Additionally, levels of fractalkine/CX3CL1, IL-2, IL-6, IL-10, RANTES/CCL5, and TNF-α at V1 were significantly associated with the post-fitting grouping (p ≤ 0.044). Low tear concentrations of specific inflammatory mediators may be used as a predictive biomarker of success for refitting symptomatic CL wearers with daily disposable CLs. However, complementary treatments might be required for symptomatic CL wearers with higher levels of these inflammatory molecules.