cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Trail of the Invisible: Blue Globular Clusters Trace the Radial Density Distribution of the Dark Matter -- Case Study of NGC 4278
Creators: name: Kluge, Matthias
name: Remus, Rhea-Silvia
name: Babyk, Iurii V.
name: Forbes, Duncan A.
name: Dolfi, Arianna
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present new, deep optical observations of the early-type galaxy NGC 4278, which is located in a small loose group. We find that the galaxy lacks fine substructure, i.e., it appears relaxed, out to a radius of $\sim$70 kpc. Our $g$- and $i$-band surface brightness profiles are uniform down to our deepest levels of $\sim$28 mag arcsec$^{-2}$. This spans an extremely large radial range of more than 14 half-mass radii. Combined with archival globular cluster (GC) number density maps and a new analysis of the total mass distribution obtained from archival Chandra X-ray data, we find that the red GC subpopulation traces well the stellar mass density profile from 2.4 out to even 14 half-mass radii, while the blue GC subpopulation traces the total mass density profile of the galaxy over a large radial range. Our results reinforce the scenario that red GCs form mostly in-situ along with the stellar component of the galaxy, while the blue GCs are more closely aligned with the total mass distribution in the halo and were accreted along with halo matter. We conclude that for galaxies where the X-ray emission from the hot halo is too faint to be properly observable and as such is not available to measure the dark matter profile, the blue GC population can be used to trace this dark matter component out to large radii.
description: 11 pages, 10 figures, 1 table. Accepted for publication in MNRAS
The fate of the weakly-bound $ψ(2s)$ in nuclear matter
Creators: name: Durham, J. Matthew
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We present new results of a completed PHENIX analysis of $ψ(2s)$ modification at midrapidity in 200 GeV $d+$Au collisions. Strong suppression of the $ψ(2s)$ relative to the $J/ψ$ is observed. This difference in suppression is too strong to be explained by breakup effects in the nucleus, due to the short nuclear crossing times at RHIC. Given the observation of long range correlations in $p(d)+$A collisions at LHC and RHIC, consistent with hydrodynamics, these observations raise interesting questions about the mechanism of $ψ(2s)$ suppression when it is produced in a nuclear target. In 2012, the PHENIX Collaboration installed the FVTX, a silicon tracker that precisely measures muon pair opening angles prior to any multiple scattering in the muon arm absorber, and thus provides an improved dimuon mass resolution. The FVTX allows the $ψ(2s)$ to be separated from the $J/ψ$ at forward and backward rapidity for the first time at RHIC. We present new results on $ψ(2s)$ production in $p+p$ collisions at $\sqrt{s} = 510$ GeV from the 2013 data set.
description: proceedings of Quark Matter 2014
title: Etes-vous hypertendus ? Pensez à agir
title: l'impact de l'infirmier dans le contrôle de la pression artérielle à l'aide de l'éduation thérapeutique
titleType: Subtitle
Creators: name: Cucchia, Sarah
name: Saraiva, Carina
name: Bourgnon, Jonas
Publisher: name: Unknown
Year: 0
Subjects: subject: Hypertension artérielle
subject: Education thérapeutique

description: Ce travail met en évidence que les compétences éducationnelles de l'infirmier dans la prise en soin des patients souffrant d'hypertension artérielle sont essentielles.
Intelligenza artificiale e risoluzione delle controversie
Creators: name: Panariello, Alessandra
Publisher: name: Universita degli studi di Salerno
Year: 2022
Subjects: subject: IUS/01 DIRITTO PRIVATO
subject: Intelligenza Artificiale

description: 2020 - 2021
description: La società muta continuamente e la tecnologia è qualcosa di cui non riusciamo più a fare a meno, ciò di cui necessitiamo per affrontare le sfide più disparate della quotidianità. A tale evoluzione non sfugge il mondo del diritto. Sempre più si discute della possibilità che l’intelligenza artificiale assuma un ruolo cardine nella risoluzione delle controversie. Tuttavia, ciò che non va dimenticato è che il miglior modo per sfruttare le potenzialità dell’IA è quello di ricorrere ad una contaminazione tra uomo e macchina. In questa prospettiva, opportuno è un approccio cauto relativamente alla collocazione dell’IA nel sistema-giustizia. [a cura dell'Autore]
description: Society changes constantly and technology is something we can no longer do without, what we need to face the most disparate challenges of everyday life. The world of law does not escape this evolution. There is increasing discussion about the possibility of artificial intelligence taking on a pivotal role in resolving disputes. However, what should not be forgotten is that the best way to exploit the potential of AI is to resort to contamination between man and machine. In this perspective, a cautious approach is appropriate in relation to the placement of AI in the justice system. [edited by Author]
RAD1 Controls the Meiotic Expansion of the Human HRAS1 Minisatellite in Saccharomyces cerevisiae
Creators: name: Edmiston, S. N.
name: Kirkpatrick, D. T.
name: Jauert, P. A.
name: Conway, K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Minisatellite DNA is repetitive DNA with a repeat unit length from 15 to 100 bp. While stable during mitosis, it destabilizes during meiosis, altering both in length and in sequence composition. The basis for this instability is unknown. To investigate the factors controlling minisatellite stability, a minisatellite sequence 3′ of the human HRAS1 gene was introduced into the Saccharomyces cerevisiae genome, replacing the wild-type HIS4 promoter. The minisatellite tract exhibited the same phenotypes in yeast that it exhibited in mammalian systems. The insertion stimulated transcription of the HIS4 gene; mRNA production was detected at levels above those seen with the wild-type promoter. The insertion stimulated meiotic recombination and created a hot spot for initiation of double-strand breaks during meiosis in the regions immediately flanking the repetitive DNA. The tract length altered at a high frequency during meiosis, and both expansions and contractions in length were detected. Tract expansion, but not contraction, was controlled by the product of the RAD1 gene. RAD1 is the first gene identified that controls specifically the expansion of minisatellite tracts. A model for tract length alteration based on these results is presented.
title: Douleur chronique et interculturalité
title: approche infirmière par les stratégies de coping
titleType: Subtitle
Creators: name: Blanc, Lauriane
name: Cardamoni, Morgane
Publisher: name: Unknown
Year: 0
Subjects: subject: Douleur chronique
subject: Soins infirmiers interculturels, Coping

description: En Suisse, le contexte d'interculturalité est de plus en plus présent dans le domaine hospitalier et engendre un bon nombre de questionnements pratiques. La douleur chronique représente une proportion importante dans l'attente à la santé de la population. Les stratégies de coping sont mobilisées par le patient pour tendre vers une meilleure gestion de la douleur chronique et amoindrir les impacts négatifs sur la qualité de vie.
Complexity of Eccentricities and All-Pairs Shortest Paths in the Quantum CONGEST Model
Creators: name: Wang, ChengSheng
name: Wu, Xudong
name: Yao, Penghui
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Computing the distance parameters of a network, including the diameter, radius, eccentricities and the all-pairs shortest paths (APSP) is a central problem in distributed computing. This paper investigates he dtistance parameters in the quantum CONGEST models and establishes almost linear lower bounds on eccentricities and APSP, which match the classical upper bounds. Our results imply that there is not quantum speedup for these two problems. In contrast with the diameter and radius, exchanging quantum messages is able to save the communication when the networks have low diameters [Le Gall and Magniez, PODC 2018]. We obtain the lower bounds via a reduction from the two-way quantum communication complexity of the set intersection [Razborov, Izvestiya Mathematics 2003].
description: 16 pages. invited paper on SPIN, Special Issue on Quantum Algorithms and Software
title: Forecasting the Impact of Technical Change on Employment: Methodological Reflexions and Propositions for Research
Creators: name: Boyer, Robert
Year: 2017

description: Paper provided by CEPREMAP in its series CEPREMAP Working Papers (Couverture Orange) with number 8202. - First Draft July 1981. - Mit Beilage: "de la part du Centre d'Etudes Prospectives d'Economie Mathématique Appliquées à la Planification CEPREMAP avec les compliments des auteurs".
description: 23 Blätter, orangefarbener Umschlag
RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming Activity
Creators: name: Korus, M.
name: Whitehead, I. P.
name: Worthylake, D. K.
name: Mahon, G. M.
name: Rossman, K. L.
name: Cheng, L.
name: Sondek, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Dbs is a Rho-specific guanine nucleotide exchange factor (RhoGEF) that exhibits transforming activity when overexpressed in NIH 3T3 mouse fibroblasts. Like many RhoGEFs, the in vitro catalytic activity of Dbs is not limited to a single substrate. It can catalyze the exchange of GDP for GTP on RhoA and Cdc42, both of which are expressed in most cell types. This lack of substrate specificity, which is relatively common among members of the RhoGEF family, complicates efforts to determine the molecular basis of their transforming activity. We have recently determined crystal structures of several RhoGEFs bound to their cognate GTPases and have used these complexes to predict structural determinants dictating the specificities of coupling between RhoGEFs and GTPases. Guided by this information, we mutated Dbs to alter significantly its relative exchange activity for RhoA versus Cdc42 and show that the transformation potential of Dbs correlates with exchange on RhoA but not Cdc42. Supporting this conclusion, oncogenic Dbs activates endogenous RhoA but not endogenous Cdc42 in NIH 3T3 cells. Similarly, a competitive inhibitor that blocks RhoA activation also blocks Dbs-mediated transformation. In conclusion, this study highlights the usefulness of specificity mutants of RhoGEFs as tools to genetically dissect the multiple signaling pathways potentially activated by overexpressed or oncogenic RhoGEFs. These ideas are exemplified for Dbs, which is strongly implicated in the transformation of NIH 3T3 cells via RhoA and not Cdc42.
Phonologyical voicing contrasts in Australian Aboriginal languages
Creators: name: Austin, Peter
Publisher: name: La Trobe
Year: 2023

description: It is widely known that the phonological systems of Australian Aboriginal languages show many similarities right across the continent. One characteristic of these systems that has been often reported is the lack in most languages of a phonological contrast between voiced and voiceless stops. This paper is an investigation of the occurrence of such a contrast in a number of widely scattered languages. It will be shown that, in a number of instances, phonological voicing is a recent historical development in the languages which have it, and the contrast has been subject to linguistic diffusion in one of the areas where it is found. Certain generalisations about the types of phonological voicing contrasts that tend to be found in Australia are also advanced.
The Histone 3'-Terminal Stem-Loop-Binding Protein Enhances Translation through a Functional and Physical Interaction with Eukaryotic Initiation Factor 4G (eIF4G) and eIF3
Creators: name: Ling, J.
name: Morley, S. J.
name: Marzluff, W. F.
name: Pain, V. M.
name: Gallie, D. R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Metazoan cell cycle-regulated histone mRNAs are unique cellular mRNAs in that they terminate in a highly conserved stem-loop structure instead of a poly(A) tail. Not only is the stem-loop structure necessary for 3′-end formation but it regulates the stability and translational efficiency of histone mRNAs. The histone stem-loop structure is recognized by the stem-loop-binding protein (SLBP), which is required for the regulation of mRNA processing and turnover. In this study, we show that SLBP is required for the translation of mRNAs containing the histone stem-loop structure. Moreover, we show that the translation of mRNAs ending in the histone stem-loop is stimulated in Saccharomyces cerevisiae cells expressing mammalian SLBP. The translational function of SLBP genetically required eukaryotic initiation factor 4E (eIF4E), eIF4G, and eIF3, and expressed SLBP coisolated with S. cerevisiae initiation factor complexes that bound the 5′ cap in a manner dependent on eIF4G and eIF3. Furthermore, eIF4G coimmunoprecipitated with endogenous SLBP in mammalian cell extracts and recombinant SLBP and eIF4G coisolated. These data indicate that SLBP stimulates the translation of histone mRNAs through a functional interaction with both the mRNA stem-loop and the 5′ cap that is mediated by eIF4G and eIF3.
title: Soins infirmiers pédiatriques
title: des propositions d'interventions pour un meilleur vécu du stress parental
titleType: Subtitle
Creators: name: Berset, Jenny
name: Chanez, Marie
name: Stoehr. Lydia
Publisher: name: Unknown
Year: 0
Subjects: subject: Pédiatrie
subject: Relation soignant-famille
subject: Hospitalisation
subject: Stress
subject: Soins intensifs

description: De nombreuses études démontrent que les parents expérimentent un stress important lors de l'hospitalisation de leur enfant aux soins intensifs pédiatriques. Un certain nombre de facteurs de stress ont été identifiés, tels que l'apparence de l'enfant, les bruits et lumières, les procédures, la communication avec l'équipe soignante, les comportements et émotions de l'enfant, les comportements de l'équipe soignante et l'altération du rôle parental.
Substrate-transferred GaAs/AlGaAs crystalline coatings for gravitational-wave detectors: A review of the state of the art
Creators: name: Cole, G. D.
name: Ballmer, S.
name: Billingsley, G.
name: Cataño-Lopez, S. B.
name: Fejer, M.
name: Fritschel, P.
name: Gretarsson, A. M.
name: Harry, G. M.
name: Kedar, D.
name: Legero, T.
name: Makarem, C.
name: Penn, S. D.
name: Reitze, D.
name: Steinlechner, J.
name: Sterr, U.
name: Tanioka, S.
name: Truong, G. -W.
name: Ye, J.
name: Yu, J.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Optics (physics.optics)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: In this Perspective we summarize the status of technological development for large-area and low-noise substrate-transferred GaAs/AlGaAs (AlGaAs) crystalline coatings for interferometric gravitational-wave (GW) detectors. These topics were originally presented in a workshop† bringing together members of the GW community from the laser interferometer gravitational-wave observatory (LIGO), Virgo, and KAGRA collaborations, along with scientists from the precision optical metrology community, and industry partners with extensive expertise in the manufacturing of said coatings. AlGaAs-based crystalline coatings present the possibility of GW observatories having significantly greater range than current systems employing ion-beam sputtered mirrors. Given the low thermal noise of AlGaAs at room temperature, GW detectors could realize these significant sensitivity gains, while potentially avoiding cryogenic operation. However, the development of large-area AlGaAs coatings presents unique challenges. Herein, we describe recent research and development efforts relevant to crystalline coatings, covering characterization efforts on novel noise processes, as well as optical metrology on large-area (~10 cm diameter) mirrors. We further explore options to expand the maximum coating diameter to 20 cm and beyond, forging a path to produce low-noise AlGaAs mirrors amenable to future GW detector upgrades, while noting the unique requirements and prospective experimental testbeds for these novel materials.
description: 13pages, 3 figures
title: Technology gaps and cost-based adjustments
Creators: name: Dosi, Giovanni
Year: 2017
Subjects: subject: Aussenhandel

description: Paper prepared for the conference on "The Dynamics of Employment and Technology: Theories and Policies", Udine, Italy, September 1-3, 1983. This paper is part of a research project on Technology, Italian International Competitiveness and the Energy Constraint, Instituto Ricerche Sociale, Milan, Italy, sponsored by the Italian Energy Commission (ENEA).
description: Preprint des Zeitschriftenartikels (Kopie verkleinert auf 2 Seiten pro Seite), 11 Blätter, paginiert 1-40 und Titelseite, mit handschriftlichen Anmerkungen und Anstreichungen von Josef Steindl
Charge fluctuations in the unconventional metallic state of Li0.9Mo6O17
Creators: name: Merino, J.
name: Alvarez, J. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Charge fluctuations in the quasi-one-dimensional material Li0.9Mo6O17 are analyzed based on a multi orbital extended Hubbard model. A charge ordering transition induced by Coulomb repulsion is found with a charge ordering pattern different from a conventional charge density wave driven by Fermi surface nesting. The metallic state displays a characteristic charge collective mode which softens signalling the proximity to the transition. We argue that the strong scattering between electrons generated by these charge order fluctuations can lead to the unconventional metallic state observed above the superconducting transition temperature in Li0.9Mo6O17.
description: 5 pages, 4 figures, typos corrected and references added
Quantum Complexity of Weighted Diameter and Radius in CONGEST Networks
Creators: name: Wu, Xudong
name: Yao, Penghui
Publisher: name: arXiv
Year: 2022
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Quantum Physics (quant-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: This paper studies the round complexity of computing the weighted diameter and radius of a graph in the quantum CONGEST model. We present a quantum algorithm that $(1+o(1))$-approximates the diameter and radius with round complexity $\widetilde O\left(\min\left\{n^{9/10}D^{3/10},n\right\}\right)$, where $D$ denotes the unweighted diameter. This exhibits the advantages of quantum communication over classical communication since computing a $(3/2-\varepsilon)$-approximation of the diameter and radius in a classical CONGEST network takes $\widetildeΩ(n)$ rounds, even if $D$ is constant [Abboud, Censor-Hillel, and Khoury, DISC '16]. We also prove a lower bound of $\widetildeΩ(n^{2/3})$ for $(3/2-\varepsilon)$-approximating the weighted diameter/radius in quantum CONGEST networks, even if $D=Θ(\log n)$. Thus, in quantum CONGEST networks, computing weighted diameter and weighted radius of graphs with small $D$ is strictly harder than unweighted ones due to Le Gall and Magniez's $\widetilde O\left(\sqrt{nD}\right)$-round algorithm for unweighted diameter/radius [PODC '18].
description: 24 pages. accepted by PODC 2022
The Stem-Loop Binding Protein Is Required for Efficient Translation of Histone mRNA In Vivo and In Vitro
Creators: name: Sanchez, R.
name: Marzluff, W. F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Metazoan replication-dependent histone mRNAs end in a conserved stem-loop rather than in the poly(A) tail found on all other mRNAs. The 3′ end of histone mRNA binds a single class of proteins, the stem-loop binding proteins (SLBP). In Xenopus, there are two SLBPs: xSLBP1, the homologue of the mammalian SLBP, which is required for processing of histone pre-mRNA, and xSLBP2, which is expressed only during oogenesis and is bound to the stored histone mRNA in Xenopus oocytes. The stem-loop is required for efficient translation of histone mRNAs and substitutes for the poly(A) tail, which is required for efficient translation of other eucaryotic mRNAs. When a rabbit reticulocyte lysate is programmed with uncapped luciferase mRNA ending in the histone stem-loop, there is a three- to sixfold increase in translation in the presence of xSLBP1 while xSLBP2 has no effect on translation. Neither SLBP affected the translation of a luciferase mRNA ending in a mutant stem-loop that does not bind SLBP. Capped luciferase mRNAs ending in the stem-loop were injected into Xenopus oocytes after overexpression of either xSLBP1 or xSLBP2. Overexpression of xSLBP1 in the oocytes stimulated translation, while overexpression of xSLBP2 reduced translation of the luciferase mRNA ending in the histone stem-loop. A small region in the N-terminal portion of xSLBP1 is required to stimulate translation both in vivo and in vitro. An MS2-human SLBP1 fusion protein can activate translation of a reporter mRNA ending in an MS2 binding site, indicating that xSLBP1 only needs to be recruited to the 3′ end of the mRNA but does not need to be directly bound to the histone stem-loop to activate translation.
Le dépistage de l’état confusionnel aigu chez les personnes âgées dans les services d’urgence Tiré
Creators: name: Aubert, Céline
name: Tanner, Lauriane
Publisher: name: Unknown
Year: 0
Subjects: subject: Démence
subject: Confusion aigue
subject: Personne âgée
subject: Urgence
subject: Dépistage

description: Ce travail de Bachelor s'intéresse aux outils pouvant aider les infirmières à dépister l’état confusionnel aigu dans les services d’urgence. L’infirmière a un rôle central à jouer dans le dépistage de l’état confusionnel, car elle se trouve en première ligne auprès du patient. En complément à l’évaluation clinique, l’utilisation d’un outil peut aider au dépistage, et ainsi renforcer le jugement infirmier.
Entre bulle technologique et soins humanistes, un défi infirmier
Creators: name: Ammann, Pauline
name: Brélaz, Maïlys
Publisher: name: Unknown
Year: 0
Subjects: subject: Technologie
subject: Surveillance infirmière
subject: Soins intensifs
subject: Relation soignant-soigné

description: Le but de cette revue de littérature est d’investiguer la place des technologies de surveillance en soins intensifs ainsi que leurs influences sur l’application du concept de caring de Jean Watson. Par la suite, en se basant sur les conclusions, nous proposerons des recommandations pour la pratique afin d’harmoniser la prise en soin des patients et la cohabitation infirmièremachine. Notre question de recherche est la suivante: Est-ce que la technologie de surveillance a une influence sur l’application du concept de human caring en unité de soins intensifs ? Les sept articles retenus ont tous amené des éléments semblables, répondant à notre problématique. Les principaux sont: ● une déshumanisation du patient ● une perte de l’individualité du patient ● une altération de la relation soignant-soigné.
Graph Rationalization with Environment-based Augmentations
Creators: name: Liu, Gang
name: Zhao, Tong
name: Xu, Jiaxin
name: Luo, Tengfei
name: Jiang, Meng
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Rationale is defined as a subset of input features that best explains or supports the prediction by machine learning models. Rationale identification has improved the generalizability and interpretability of neural networks on vision and language data. In graph applications such as molecule and polymer property prediction, identifying representative subgraph structures named as graph rationales plays an essential role in the performance of graph neural networks. Existing graph pooling and/or distribution intervention methods suffer from lack of examples to learn to identify optimal graph rationales. In this work, we introduce a new augmentation operation called environment replacement that automatically creates virtual data examples to improve rationale identification. We propose an efficient framework that performs rationale-environment separation and representation learning on the real and augmented examples in latent spaces to avoid the high complexity of explicit graph decoding and encoding. Comparing against recent techniques, experiments on seven molecular and four polymer real datasets demonstrate the effectiveness and efficiency of the proposed augmentation-based graph rationalization framework.
description: Accepted by KDD 2022
Promotion de la qualité de vie chez le jeune adulte atteint du VIH
Creators: name: Alves Ribeiro, Jeremy
name: Crestani, Héloïse
name: Ferrigno, Graziella
Publisher: name: Unknown
Year: 0
Subjects: subject: Qualité de vie
subject: Adolescent
subject: Santé

description: Depuis l’apparition des traitements antirétroviraux et l’augmentation de leur accessibilité dans nos pays, le statut de la maladie du VIH a changé. Cette maladie mortelle est désormais une maladie chronique. La chronicité de cette maladie et son traitement impactent très nettement la qualité de vie des personnes VIH positives, de plus, ces patients sont toujours victimes de stigmatisation. La qualité de vie de ces personnes semble dorénavant au coeur de la prise en charge infirmière. En effet, des interventions infirmières permettant d’améliorer et de promouvoir la qualité de vie de ces patients sont nécessaires. Le rôle infirmier qui émerge est l’évaluation clinique systématique de l’état de santé physique et psychique, l’investigation du domaine socio-économique de ces patients afin de les orienter au besoin vers les services appropriés, promouvoir leur satisfaction sexuelle en l’incluant dans le recueil de données, encourager la spiritualité si présente comme stratégie d’adaptation à la maladie en proposant l’aide de professionnels religieux.
The SWI/SNF Chromatin-Remodeling Factor Stimulates Repair by Human Excision Nuclease in the Mononucleosome Core Particle
Creators: name: Sancar, A.
name: Hara, R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: To investigate the role of chromatin remodeling in nucleotide excision repair, we prepared mononucleosomes with a 200-bp duplex containing an acetylaminofluorene-guanine (AAF-G) adduct at a single site. DNase I footprinting revealed a well-phased nucleosome structure with the AAF-G adduct near the center of twofold symmetry of the nucleosome core. This mononucleosome substrate was used to examine the effect of the SWI/SNF remodeling complex on the activity of human excision nuclease reconstituted from six purified excision repair factors. We found that the three repair factors implicated in damage recognition, RPA, XPA, and XPC, stimulate the remodeling activity of SWI/SNF, which in turn stimulates the removal of the AAF-G adduct from the nucleosome core by the excision nuclease. This is the first demonstration of the stimulation of nucleotide excision repair of a lesion in the nucleosome core by a chromatin-remodeling factor and contrasts with the ACF remodeling factor, which stimulates the removal of lesions from internucleosomal linker regions but not from the nucleosome core.
L'accompagnement infirmier du patient diabétique dans l'autogestion de sa maladie
Creators: name: Ahmidou, Rachid
name: Kervella, Mael
Publisher: name: Unknown
Year: 0
Subjects: subject: Diabète
subject: Education du patient
subject: Entretien motivationnel
subject: Information du patient
subject: Relation soignant-soigné

description: L’éducation thérapeutique représente la pierre angulaire pour accompagner le patient dans l’autogestion de son diabète. Elle doit faire partie intégrante des soins habituels fournis par l’infirmière et des concepts tels que l’entretien motivationnel, le sentiment d’auto-efficacité, le soutien des proches ainsi que la littératie sont importants à prendre en compte. Ces interventions que nous préconisons sont utiles non seulement pour guider le patient à gérer sa maladie au quotidien mais également pour améliorer sa qualité de vie et éviter ou retarder les complications à long terme liées à l’hyperglycémie chronique. Les infirmières à domicile ont donc un rôle central à jouer dans l’accompagnement des patients diabétiques et nous encourageons une meilleure formation de ces professionnels à l’éducation thérapeutique.
Autophosphorylation of the Catalytic Subunit of the DNA-Dependent Protein Kinase Is Required for Efficient End Processing during DNA Double-Strand Break Repair
Creators: name: Douglas, P.
name: Reddy, Y. V. R.
name: Meek, K.
name: Ding, Q.
name: Lees-Miller, S. P.
name: Ramsden, D. A.
name: Woods, T.
name: Wang, W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: The DNA-dependent protein kinase (DNA-PK) plays an essential role in nonhomologous DNA end joining (NHEJ) by initially recognizing and binding to DNA breaks. We have shown that in vitro, purified DNA-PK undergoes autophosphorylation, resulting in loss of activity and disassembly of the kinase complex. Thus, we have suggested that autophosphorylation of the DNA-PK catalytic subunit (DNA-PKcs) may be critical for subsequent steps in DNA repair. Recently, we defined seven autophosphorylation sites within DNA-PKcs. Six of these are tightly clustered within 38 residues of the 4,127-residue protein. Here, we show that while phosphorylation at any single site within the major cluster is not critical for DNA-PK's function in vivo, mutation of several sites abolishes the ability of DNA-PK to function in NHEJ. This is not due to general defects in DNA-PK activity, as studies of the mutant protein indicate that its kinase activity and ability to form a complex with DNA-bound Ku remain largely unchanged. However, analysis of rare coding joints and ends demonstrates that nucleolytic end processing is dramatically reduced in joints mediated by the mutant DNA-PKcs. We therefore suggest that autophosphorylation within the major cluster mediates a conformational change in the DNA-PK complex that is critical for DNA end processing. However, autophosphorylation at these sites may not be sufficient for kinase disassembly.
title: Regard phénoménologique sur les hallucinations
title: une perspective pour les soins infirmiers ?
titleType: Subtitle
Creators: name: Chabloz, Emilien
Publisher: name: Unknown
Year: 0
Subjects: subject: SOINS INFIRMIERS EN PSYCHIATRIE
subject: HALLUCINATION
subject: SCHIZOPHRENIE
subject: VIE QUOTIDIENNE

description: Les hallucinations acoustico-verbales sont un phénomène handicapant et stressant rencontré chez les patients schizophrènes. Ces voix ont un effet tel sur la vie quotidienne des patients en souffrant, que leur accompagnement est devenu un objectif important de la prise en charge. Cette expérience vécue est souvent mal perçue lorsque les patients désirent en parler avec les infirmiers en psychiatrie ou du moins ils se sentent insuffisamment écoutés par les professionnels de la santé.
description: Mémoire de Bachelor : Haute Ecole de la Santé La Source, 2015
The optical properties of a turbid reservoir and its phytoplankton in relation to photosynthesis and growth (Mount Bold Reservoir, South Australia)
Creators: name: Oliver, R. L
name: Ganf, G. G
Publisher: name: La Trobe
Year: 2023

description: Murray-Darling Freshwater Research Centre

MDFRC item.

In situ light measurements were used to obtain information on inherent and apparent optical properties. The average vertical attenuation coefficient Kd(ave) varied from 1.1 to 4.6 In units m–1 During three periods the variation in Kd(ave) correlated with changes in chlorophyll a concentration and specific attenuation coefficients Ks, of 0.013, 0.014 and 0.022 m2 mg Chl a–1 were calculated. Chlorophyll-specific diffuse absorption coefficients (A,) for these periods were 0.012. 0.013 and 0.017 m2 mg Chl a–1 and only varied significantly from estimates of Ks in the period when scattering was intense. Absorption coefficients a(zmid) and scattering coefficients b(zmid) calculated for the mid-point of the euphotic zone ranged between 0.45 and 2.9 m and 3.5–52.0 m respectively. Chlorophyll-specific absorption coefficients Ka, of 0.005, 0.006 and 0.007 m2 mg Chl a–1 and scattering coefficients Kb of 0.05. 0.09 and 0.191 m2 mg Chl a–1 were measured during the three periods. The high Kb value occurred when gas-vacuolate cyanobactena were dominant. Algal photosynthesis and light absorption were related through the maximum quantum yield m which varied between 0.019 and 0.11 mol C Einstein–1 while average quantum yields a, varied between 0.006 and 0.024 with a mean of 0.013 mol C Einstein–1 A comparison of changes in the mean irradiance of the mixed zone and chlorophyll concentration indicated that growth was light limited below 0.04–0.05 Einsteins absorbed mg Chl a–1 day–1.
BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation
Creators: name: Conlon, F. L.
name: Ren, R.
name: Wu, Y.
name: Bode, C.
name: Patterson, C.
name: Bautch, V. L.
name: Moser, M.
name: Aitsebaomo, J.
name: Binder, O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: The development of endothelial cell precursors is essential for vasculogenesis. We screened for differentially expressed transcripts in endothelial cell precursors in developing mouse embryoid bodies. We cloned a complete cDNA encoding a protein that contains an amino-terminal signal peptide, five cysteine-rich domains, a von Willebrand D domain, and a trypsin inhibitor domain. We termed this protein BMPER (bone morphogenetic protein [BMP]-binding endothelial cell precursor-derived regulator). BMPER is specifically expressed in flk-1-positive cells and parallels the time course of flk-1 induction in these cells. In situ hybridization in mouse embryos demonstrates dorsal midline staining and staining of the aorto-gonadal-mesonephric region, which is known to host vascular precursor cells. BMPER is a secreted protein that directly interacts with BMP2, BMP4, and BMP6 and antagonizes BMP4-dependent Smad5 activation. In Xenopus embryos, ventral injection of BMPER mRNA results in axis duplication and downregulation of the expression of Xvent-1 (downstream target of Smad signaling). In an embryoid body differentiation assay, BMP4-dependent differentiation of endothelial cells in embryoid bodies is also antagonized by BMPER. Taken together, our data indicate that BMPER is a novel BMP-binding protein that is expressed by endothelial cell precursors, has BMP-antagonizing activity, and may play a role in endothelial cell differentiation by modulating local BMP activity.
Ermakov Systems with Multiplicative Noise
Creators: name: Cervantes-Lopez, E.
name: Espinoza, P. B.
name: Gallegos, A.
name: Rosu, H. C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Using the Euler-Maruyama numerical method, we present calculations of the Ermakov-Lewis invariant and the dynamic, geometric, and total phases for several cases of stochastic parametric oscillators, including the simplest case of the stochastic harmonic oscillator. The results are compared with the corresponding numerical noiseless cases to evaluate the effect of the noise. Besides, the noiseless cases are analytic and their analytic solutions are briefly presented. The Ermakov-Lewis invariant is not affected by the multiplicative noise in the three particular examples presented in this work, whereas there is a shift effect in the case of the phases
description: 12 pages, 4 figures, 22 references
Piezoresistance characterization of silicon nanowires in uniaxial and isostatic pressure variation
Creators: name: Fakhri, Elham
name: Plugaru, Rodica
name: Sultan, Muhammad Taha
name: Kristinsson, Thorsteinn Hanning
name: Árnason, Hákon Örn
name: Plugaru, Neculai
name: Manolescu, Andrei
name: Ingvarsson, Snorri
name: Svavarsson, Halldor Gudfinnur
Publisher: name: arXiv
Year: 2022
Subjects: subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Silicon nanowires (SiNWs) are known to exhibit large piezoresistance (PZR) effect, making it suitable for various sensing applications. Here, we report the results of a PZR investigation on randomly distributed and interconnected vertical silicon nanowire arrays as a pressure sensor. The samples were produced from p-type (100) Si wafers using a silver catalysed top-down etching process. The piezoresistance response of these SiNW arrays was analysed by measuring their I-V characteristics under applied uniaxial as well as isostatic pressure. The interconnected SiNWs exhibit increased mechanical stability in comparison with separated or periodic nanowires. The repeatability of the fabrication process and statistical distribution of measurements were also tested on several samples from different batches. A sensing resolution down to roughly \SI{1}{\milli\bar} pressure was observed with uniaxial force application, and more than two orders of magnitude resistance variation was determined for isostatic pressure below atmospheric pressure.
description: 7 pages 10 figures
title: Lorsque l'accouchement idéalisé se complique …
title: quelles sont les interventions infirmières adaptées aux besoins de la mère hospitalisée ?
titleType: Subtitle
Creators: name: Chelliah, Savita
name: Liengme, Anouk
Publisher: name: Unknown
Year: 0
Subjects: subject: MATERNITE
subject: ACCOUCHEMENT
subject: COMPLICATION
subject: INTERVENTION INFIRMIERE
subject: MERE
subject: HOSPITALISATION

description: L’objectif de notre revue de littérature est de comprendre l’expérience des mères lors d’un accouchement compliqué et de suggérer des pistes d’interventions infirmières adaptées à leurs besoins.
Améliorer la qualité de l'accompagnement des parents ayant un enfant en soins palliatifs
Creators: name: Dumas, Céline
name: Spycher, Noémie
Publisher: name: Unknown
Year: 0
Subjects: subject: ACCOMPAGNEMENT
subject: PARENTS
subject: ENFANT
subject: PEDIATRIE
subject: SOINS PALLIATIFS

description: Quelles interventions l’infirmière peut-elle mettre en place pour répondre aux besoins des parents ayant un enfant en soins palliatifs, dans une perspective d’amélioration de la qualité de l’accompagnement?
description: Mémoire de Bachelor : Haute Ecole de la Santé La Source, 2015
First Principles Assessment of CdTe as a Tunnel Barrier at the $\mathbfα$-Sn/InSb Interface
Creators: name: Jardine, Malcolm J. A.
name: Dardzinski, Derek
name: Yu, Maituo
name: Purkayastha, Amrita
name: Chen, A. -H.
name: Chang, Yu-Hao
name: Engel, Aaron
name: Strocov, Vladimir N.
name: Hocevar, Moïra
name: Palmstrøm, Chris J.
name: Frolov, Sergey M.
name: Marom, Noa
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Majorana zero modes, with prospective applications in topological quantum computing, are expected to arise in superconductor/semiconductor interfaces, such as $β$-Sn and InSb. However, proximity to the superconductor may also adversely affect the semiconductor's local properties. A tunnel barrier inserted at the interface could resolve this issue. We assess the wide band gap semiconductor, CdTe, as a candidate material to mediate the coupling at the lattice-matched interface between $α$-Sn and InSb. To this end, we use density functional theory (DFT) with Hubbard U corrections, whose values are machine-learned via Bayesian optimization (BO) [npj Computational Materials 6, 180 (2020)]. The results of DFT+U(BO) are validated against angle resolved photoemission spectroscopy (ARPES) experiments for $α$-Sn and CdTe. For CdTe, the z-unfolding method [Advanced Quantum Technologies, 5, 2100033 (2022)] is used to resolve the contributions of different $k_z$ values to the ARPES. We then study the band offsets and the penetration depth of metal-induced gap states (MIGS) in bilayer interfaces of InSb/$α$-Sn, InSb/CdTe, and CdTe/$α$-Sn, as well as in tri-layer interfaces of InSb/CdTe/$α$-Sn with increasing thickness of CdTe. We find that 16 atomic layers (3.5 nm) of CdTe can serve as a tunnel barrier, effectively shielding the InSb from MIGS from the $α$-Sn. This may guide the choice of dimensions of the CdTe barrier to mediate the coupling in semiconductor-superconductor devices in future Majorana zero modes experiments.
title: Adhérence au traitement antirétroviral
title: pistes d'interventions infirmières améliorant la "readiness" et l'auto-efficacité
titleType: Subtitle
Creators: name: Vanbeneden, Fanny
name: Wirthner, Morgane
Publisher: name: Unknown
Year: 0
Subjects: subject: SIDA
subject: TRAITEMENT
subject: ADHERENCE
subject: RELATION SOIGNANT-SOIGNE

description: Le virus de l’immunodéficience humaine (VIH) est un problème de santé publique mondial. L’introduction des traitements antirétroviraux (TAR) a mené à la chronicisation de la maladie et a introduit une nouvelle problématique, celle de l’adhérence au traitement. De nombreux facteurs influencent l’adhérence. Nous avons décidé de nous concentrer sur les concepts de l’auto-efficacité et de la “readiness”. Le but de ce travail est de proposer des interventions infirmières améliorant l’adhérence thérapeutique et, à long terme, la qualité de vie des patients atteints de VIH.
description: Mémoire de Bachelor : Haute Ecole de la Santé La Source, 2015
title: Overview of the process of change in Poland
Creators: name: Sadowski, Zdzisław
Year: 2017
Subjects: subject: Polen

description: Since the goal of present economic reform is to build up a market economy modelled after the Western developed economies one can ask how fast the goal can be achieved. It seems that the progress in this respect will be quite uneven. (Auszug, S. 14)
description: Kopie des Papers, 11 Blätter
Structure and electrical behavior of silicon nanowires prepared by MACE process
Creators: name: Plugaru, R.
name: Fakhri, E.
name: Romanitan, C.
name: Mihalache, I.
name: Craciun, G.
name: Plugaru, N.
name: Árnason, H. Ö.
name: Sultan, M. T.
name: Nemnes, G. A.
name: Ingvarsson, S.
name: Svavarsson, H. G.
name: Manolescu, A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report on the structure and electrical characteristics of silicon nanowire arrays prepared by metal assisted chemical etching (MACE) method, investigated by cross-sectional scanning electron microscopy (SEM) and high resolution X-ray diffraction (HR-XRD) methods. SEM micrographs show arrays of merged parallel nanowires, with lengths of 700 nm and 1000 nm, resulted after 1.5 min and 5 min etching time, respectively. X-ray reciprocal space maps (RSMs) around Si (004) reciprocal lattice point indicate the presence of 0D structural defects rather than of extended defects. The photoluminescence spectra exhibit emission bands at 1.70 eV and 1.61 eV, with intensity significantly higher in the case of longer wires and associated with the more defected surface. The transient photoluminescence spectroscopy reveals average lifetime of 60 $μ$s and 111 $μ$s for the two SiNW arrays, which correlate with a larger density of defects states in the latest case. The I-V characteristics of the nanowires, show a memristive behavior with the applied voltage sweep rate in the range 5V/s - 0.32V/s. We attribute this behavior to trap states which control the carrier concentration, and model this effect using an equivalent circuit. Photogeneration processes under excitation wavelengths in visible domain, 405 nm - 650 nm, and under light intensity in the range 20 - 100 mW/cm$^2$ provided a further insight into the trap states.
description: 23 pages 18 figures
title: A post Keynesian model of development in a dual economy
Creators: name: Muet, Pierre-Alain
Year: 2017

description: Mit Beilage: "de la part du Centre d'Etudes Prospectives d'Economie Mathématique Appliquées à la Planification CEPREMAP avec les compliments de P.A. Muet - R. Topol".
description: Sonderdruck, 26 Blätter
Smart city and Big Data. Management degli enti pubblici locali, dalle realtà territoriali delle aree interne ai progetti di Smart Coast
Creators: name: Marrazzo, Vincenzo
Publisher: name: Universita degli studi di Salerno
Year: 2023
Subjects: subject: SECS-P/07 ECONOMIA AZIENDALE
subject: Smart
subject: Enti territoriali

description: 2021 - 2022
description: In un'ottica di Project Management e tecnica manageriale, l'obiettivo del presente elaborato, è offrire una rappresentazione concisa ed esauriente di un modello innovativo di progettazione, gestione e organizzazione delle città, emerso negli ultimi anni e diffusosi a livello nazionale e internazionale: la smart city. Il fine è dimostrare che il ripensamento delle aree urbane in chiave intelligente possa essere una delle soluzioni alle problematiche ambientali e sociali sorte in seguito alla propagazione del fenomeno, irreversibile, dell'urbanizzazione e al tempo stesso favorire la crescita economica, grazie alle opportunità offerte dalle nuove tecnologie. Si intende dunque introdurre e commentare le caratteristiche principali connesse a questo fenomeno, i requisiti e alcune iniziative di successo, fornendo una panoramica ampia del concetto di città intelligente, degli strumenti (Big Data) e degli incentivi attraverso cui è possibile realizzare quest'innovativo progetto. .. [introduzione a cura dell'Autore]
title: Transition and opening in the countries of Eastern Europe
Creators: name: Illés, Iván
Year: 2017
Subjects: subject: Osteuropa

description: Verfasser vermutlich Ivan Illes, Institut für Wirtschaftliche Planung, Budapest. - Das Paper wurde für die Ost-West Konferenz vorbereitet, die vom 17.-18. Mai 1990 in Wien stattgefunden hatte. Titel der Konferenz: New Economic Relations beween East and West - Conference of the Kreisky Commission and the Swedish Embassy in Vienna, May 17-18, 1990. Organisation der Konferenz: Unabhängige wissenschaftliche Kommission für Beschäftigungsfragen in Europa (Kreisky Commission on Employment Issues in Europe).
description: Typoskript, 9 Blätter, paginiert 2-8, letzte Seite Anhang mit Tabelle