Additional file 1 of Incident cardiovascular disease and particulate matter air pollution in South Korea using a population-based and nationwide cohort of 0.2 million adults
Creators: name: Ok-Jin Kim
name: Lee, Soo Hyun
name: Si-Hyuck Kang
name: Kim, Sun-Young
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1: Table S1. Adjusted hazard ratios and 95% confidence intervals of incident cardiovascular diseases for a 10 μg/m3 increase in long-term PM10 and PM2.5 concentrations for the previous 5 years by three health analysis models in 84,412 Seoul Metropolitan Area residents of the National Health Insurance Service-National Sample Cohort 2.0, South Korea, for 2007–2015. Table S2. Adjusted hazard ratios and 95% confidence intervals of incidence of total cardiovascular diseases and four subtypes defined as hospital admissions for a 10 μg/m3 increase in long-term PM10 and PM2.5 concentrations for the previous 5 years by five health analysis models in 196,167 subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015. Table S3. Adjusted hazard ratios and 95% confidence intervals of incident cardiovascular diseases including cardiovascular deaths for a 10 μg/m3 increase in long-term PM10 and PM2.5 concentrations for the previous 5 years by five health analysis models in 196,167 subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015. Table S4. Previous large cohort studies of the association between long-term exposure to PM10 or PM2.5 and incident cardiovascular diseases. Table S5. Summary statistics of individual-level long-term concentration of PM10 and PM2.5 across four exposure periods and the number of events and incidence of total and subtypes of cardiovascular diseases in 196,167 subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015 by the Seoul Metropolitan Area (SMA) and non-SMA. Table S6. Descriptive summary statistics of individual- and area-level characteristics, and long-term PM10 and PM2.5 concentrations of 196,167 total subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015 by diagnosis and hospitalization of cardiovascular diseases. Table S7. Descriptive summary statistics of individual- and area-level characteristics, and long-term PM10 and PM2.5 concentrations of 196,167 total subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015 by diagnosis and hospitalization of cardiovascular diseases. Figure S1. Schematic diagram of subject exclusion criteria and numbers of the National Health Insurance Service- National Sample Cohort 2.0 subjects included or excluded after the application of the criteria. Figure S2. Map of 7 metropolitan cities and 9 provinces in South Korea, 2010. Figure S3. Maps of predicted annual- average concentrations of PM10 across 245,248, and 252 districts in South Korea by 2002, 2007, and 2014, respectively (modified from the maps on https://tabsoft.co/2T7v6ti ). Figure S4. Box plot of the area sizes of districts by 7 metropolitan cities and 9 provinces, South Korea, in 2007. Figure S5. The concentration-response relationship between individual-level long-term concentration of PM2.5 for the previous 5 years and the incidence of total cardiovascular disease in 196,167 subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015. Figure S6. The concentration-response relationship between individual-level long-term PM2.5 concentration for the previous 5 years and the incidence of ischemic heart disease in 196,167 subjects of the National Health Insurance Service-National Sample Cohort 2.0 in South Korea for 2007–2015. Figure S7. Adjusted hazard ratios and 95% confidence intervals of incidence of total cardiovascular diseases and four subtypes defined as hospital admissions for a 10 μg/m3 increase in long-term PM10 and PM2.5 concentrations by four exposure periods. Hazard ratios were adjusted for sex, age, income, smoking, alcohol use, obesity, physical activity, comorbidity (hypertension, diabetes, or hyperlipidemia), area-level gross regional domestic products, percent of high school graduated or more, and percent of the elderly. HR, hazard ratio; CI, confidence interval; PM10, particulate matter 10 μm or less in diameter; PM2.5, particulate matter 2.5 μm or less in diameter; IHD, ischemic heart disease; MI, myocardial infarction. Figure S8. Adjusted hazard ratios and 95% confidence intervals of incident cardiovascular diseases including death from cardiovascular diseases for a 10 μg/m3 increase in long-term PM10 and PM2.5 concentrations by four exposure windows. Hazard ratios were adjusted for sex, age, income, smoking, alcohol use, obesity, physical activity, comorbidity (hypertension, diabetes, or hyperlipidemia), area-level gross regional domestic products, percent of high school graduated or more, and percent of the elderly. HR, hazard ratio; CI, confidence interval; PM10, particulate matter 10 μm or less in diameter; PM2.5, particulate matter 2.5 μm or less in diameter; IHD, ischemic heart disease; MI, myocardial infarction.