cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mousse minérale isolante : développement d’une adjuvantation biosourcée
Creators: name: Dubois, Vincent
name: Mazian, Brahim
name: Gosselin, Isabelle
name: Landry, Christophe
name: Gosselet, Fabien
name: Chaveriat, Ludovic
name: Aguibi, Kawther
name: Wirquin, Eric
name: Martin, Patrick
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: La RE 2020 favorise la construction de bâtiments peu voire non énergivores ayant un bas impact environnemental, de la production des matières premières à la démolition. L’utilisation de ressources de proximité issues de la biomasse est une réponse. Dans ce contexte, le projet ABIOBAT étudie l’utilisation de biomasses végétales présentes en région Hauts-de-France pour développer une adjuvantation biosourcée rentrant dans la composition d’une mousse isolante. ABIOBAT est un projet pluridisciplinaire dans lequel s’associent génie civil, chimie, microbiologie et toxicologie. Dans cet article, un comparatif du moussage induit par deux dérivés de protéines végétales et un adjuvant pétrosourcé est présenté ainsi que les premiers résultats des tests microbiologiques et toxicologiques sur les produits testés.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
Imagerie 3D au service de la restauration de l’Obélisque de la Concorde, Paris
Creators: name: Giovannacci, David
name: Mélinge, Yannick
name: Mertz, Jean Didier
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: L’obélisque de la Concorde est érigé depuis 1836 sur son piédestal en granite breton. Restauré en 1962, il fait l’objet d’une intervention encore en cours pour célébrer le bicentenaire de la découverte de Champollion. Soumis à la pollution atmosphérique et aux agressions du climat parisien, une campagne de restauration a été programmée pour le premier trimestre 2022. En amont de cet opération d’envergure, des tests ont été nécessaires afin de déterminer les techniques optimales de nettoyage et de consolidation de l’épiderme du granite constituant le monolithe. Dans cet étude, l’accent est mis sur les méthodes d’évaluation et de contrôle mises en œuvre, où les techniques non destructives ou non invasives occupent une place privilégiée, dans un contexte patrimoniale sensible et de suivi sur le long terme.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Creators: name: Trefny, Marcel P
name: Kirchhammer, Nicole
name: Auf Der Maur, Priska
name: Natoli, Marina
name: Schmid, Dominic
name: Germann, Markus
name: Fernandez Rodriguez, Laura
name: Herzig, Petra
name: Lötscher, Jonas
name: Akrami, Maryam
name: Stinchcombe, Jane C
name: Stanczak, Michal A
name: Zingg, Andreas
name: Buchi, Melanie
name: Roux, Julien
name: Marone, Romina
name: Don, Leyla
name: Lardinois, Didier
name: Wiese, Mark
name: Jeker, Lukas T
name: Bentires-Alj, Mohamed
name: Rossy, Jérémie
name: Thommen, Daniela S
name: Griffiths, Gillian M
name: Läubli, Heinz
name: Hess, Christoph
name: Zippelius, Alfred
Publisher: name: Apollo - University of Cambridge Repository
Year: 2023
Subjects: Article
/692/308/575
/631/67/580
/631/250/251
/692/4028/67/580
/13/31
/13/95
/13/106
/14/19
/38/91
/42/41
/82/80
/96/21
/82/1
/64/60
/45/23
article

description: Funder: Dr. Arnold U. und Susanne Huggenberger-Bischoff Stiftung zur Krebsforschung (Huggenberger-Bischoff Foundationfor Cancer Research); doi: https://doi.org/10.13039/501100007878
description: Funder: Krebsliga Beider Basel (Cancer League of Basel-City and Basel-Country); doi: https://doi.org/10.13039/501100006069
description: Funder: Krebsliga Schweiz (Ligue Suisse Contre le Cancer); doi: https://doi.org/10.13039/501100004361
description: Funder: Swiss Personalized Health Network (Swiss Personalized Oncology driver project) Medical Faculty and Department of Surgery of the University Hospital Basel
description: Tumor-specific T cells are frequently exhausted by chronic antigenic stimulation. We here report on a human antigen-specific ex vivo model to explore new therapeutic options for T cell immunotherapies. T cells generated with this model resemble tumor-infiltrating exhausted T cells on a phenotypic and transcriptional level. Using a targeted pooled CRISPR-Cas9 screen and individual gene knockout validation experiments, we uncover sorting nexin-9 (SNX9) as a mediator of T cell exhaustion. Upon TCR/CD28 stimulation, deletion of SNX9 in CD8 T cells decreases PLCγ1, Ca2+, and NFATc2-mediated T cell signaling and reduces expression of NR4A1/3 and TOX. SNX9 knockout enhances memory differentiation and IFNγ secretion of adoptively transferred T cells and results in improved anti-tumor efficacy of human chimeric antigen receptor T cells in vivo. Our findings highlight that targeting SNX9 is a strategy to prevent T cell exhaustion and enhance anti-tumor immunity.
title: Σχεδιασμός, μελέτη και κατασκευή CNC εργαλειομηχανής τριών αξόνων
title: Design, study and construction of a 3-axis milling machine
titleType: AlternativeTitle
Creators: name: Αναγνωστόπουλος, Γεώργιος
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: CNC μηχανές
Εργαλειομηχανές
Arduino UNO
Σχεδιασμός κατασκευής

description: Η Παρούσα εργασία επικεντρώνεται στον σχεδιασμό, την μελέτη και την κατασκευή μιας πιλοτικής εργαλειομηχανής 3 αξόνων εκπαιδευτικής χρήσης. Η εργασία καλύπτει τον σχεδιασμό όλων των επιμέρους στοιχείων που απαρτίζουν την εργαλειομηχανή και επεξηγεί όλα τα ηλεκτρονικά και ηλεκτρολογικά μέρη της εργαλειομηχανής καθώς και γίνεται αναφορά στον τρόπο προγραμματισμού και οδήγησης των κινητήρων ώστε να λειτουργήσει η μηχανή. Επιπλέον παρουσιάζεται η κατασκευή άλλα και δυσκολίες που συναντήθηκαν κατά της κατασκευής της. Η δοθέν προσέγγιση δίνει στον αναγνώστη μια πλήρη εικόνα της διαδικασίας και των προκλήσεων που μπορεί να συναντήσει κανείς κάρτα την κατασκευή μιας τέτοιας εργαλειομηχανής
Vulnerable Populations and the Transition to Adulthood
Creators: name: Michael Foster, E.
name: Wayne Osgood, D.
name: Courtney, Mark E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: D. Wayne Osgood, E. Michael Foster, and Mark E. Courtney examine the transition to adulthood for youth involved in social service and justice systems during childhood and adolescence. They survey the challenges faced by youth in the mental health system, the foster care system, the juvenile justice system, the criminal justice system, and special education, and by youth with physical disabilities and chronic illness, as well as runaway and homeless youth.
HARPO: beam characterization of a TPC for gamma-ray polarimetry and high angular-resolution astronomy in the MeV-GeV range
Creators: name: Wang, Shaobo
name: Bernard, Denis
name: Bruel, Philippe
name: Frotin, Mickael
name: Geerebaert, Yannick
name: Giebels, Berrie
name: Gros, Philippe
name: Horan, Deirdre
name: Louzir, Marc
name: Poilleux, Patrick
name: Semeniouk, Igor
name: Attié, David
name: Calvet, Denis
name: Colas, Paul
name: Delbart, Alain
name: Sizun, Patrick
name: Götz, Diego
name: Amano, Sho
name: Kotaka, Takuya
name: Hashimoto, Satoshi
name: Minamiyama, Yasuhito
name: Takemoto, Akinori
name: Yamaguchi, Masashi
name: Miyamoto, Shuji
name: Daté, Schin
name: Ohkuma, Haruo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: A time projection chamber (TPC) can be used to measure the polarization of gamma rays with excellent angular precision and sensitivity in the MeV-GeV energy range through the conversion of photons to e+e- pairs. The Hermetic ARgon POlarimeter (HARPO) prototype was built to demonstrate this concept. It was recently tested in the polarized photon beam at the NewSUBARU facility in Japan. We present this data-taking run, which demonstrated the excellent performance of the HARPO TPC.
description: 12 pages, 11 figures, presented at the 7th Symposium on large TPCs for low-energy rare event detection, Paris, France, 15-17 December 2014
The Greek of 2 Esdras: Signs of fluency and formal education in a literal translation
Creators: name: Matic, Mark
Publisher: name: Macquarie University
Year: 2023
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified

description: Significant efforts have been made in the last century to locate the Septuagint translations within their broader linguistic context. Once widely believed to be examples of a special Jewish-Greek dialect on account of their distinct vocabulary, morphology and syntax, these ancient translations of the Hebrew Bible are now better understood as works of non-literary post-classical Greek, showing different degrees of fidelity to the vocabulary and word order of the source texts. This realisation would not have been possible without the thousands of Greek papyrus documents unearthed in Egypt in the late 19th century and the subsequent comparative analyses of Deissmann, Thackeray, Lee, Evans and others. Lee’s studies of the Pentateuchal translations have convincingly shown that the anonymous authors were intimately familiar with the standard Greek of their times (the 3rd century BCE) and possessed a good Greek education. In doing so, Lee has mobilised these translations as significant bodies of evidence for the post-classical development of the Greek language. The later and more literal translations are yet to undergo the same corpus-based, sociolinguistic analysis and consequently enjoy a poorer reputation among biblical scholars. The language of 2 Esdras, the translation of Hebrew-Aramaic Ezra-Nehemiah, has been repeatedly characterised in modern scholarship as un-Greek, uneducated, and servile to the structure of its parent text. The following thesis seeks to improve this reputation and mobilise 2 Esdras as a useful piece of historical linguistic evidence by highlighting instances of independent language variation, higher register lexical and syntactic choices, and the idiomatic character of supposedly ungrammatical choices. These aims are achieved through close comparison of the translation and source text, and the presentation of comparable linguistic choices in the wider Greek corpus. Special attention is paid to the construction of indirect commands and the use of independent nominatives in the translation.
Effective Instruction for English Learners
Creators: name: Sánchez, Marta
name: Calderón, Margarita
name: Slavin, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The fastest-growing student population in U.S. schools today is children of immigrants, half of whom do not speak English fluently and are thus labeled English learners. Although the federal government requires school districts to provide services to English learners, it offers states no policies to follow in identifying, assessing, placing, or instructing them. Margarita Calderon, Robert Slavin, and Marta Sanchez identify the elements of effective instruction and review a variety of successful program models. During 2007-08, more than 5.3 million English learners made up 10.6 percent of the nation's K-12 public school enrollment. Wide and persistent achievement disparities between these English learners and English-proficient students show clearly, say the authors, that schools must address the language, literacy, and academic needs of English learners more effectively. Researchers have fiercely debated the merits of bilingual and English-only reading instruction. In elementary
(2061) William Beswick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The Physical and Psychological Well-Being of Immigrant Children
Creators: name: Perreira, Krista M.
name: Ornelas, India J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Poor childhood health contributes to lower socioeconomic status in adulthood. Subsequently, low socioeconomic status among parents contributes to poor childhood health outcomes in the next generation. This cycle can be particularly pernicious for vulnerable and low-income minority populations, including many children of immigrants. And because of the rapid growth in the numbers of immigrant children, this cycle also has implications for the nation as a whole. By promoting the physical well-being and emotional health of children of immigrants, health professionals and policy makers can ultimately improve the long-term economic prospects of the next generation.
Uterine natural killer cells as modulators of the maternal-fetal vasculature
Creators: name: Caron, Kathleen M.
name: Matson, Brooke C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Precise and local control of the innate immune system within the placenta is an essential component for achieving a normal and healthy pregnancy. One of the most abundant immune cells of the placenta is a subpopulation of natural killer (NK) cells that profusely populates the uterine decidua during early pregnancy. Uterine NK (uNK) cells and trophoblast cells of the placenta communicate both directly and indirectly to contribute to the critical process of spiral artery remodeling. Here, we discuss recent findings that expand our knowledge of uNK cell-trophoblast cell crosstalk and the important role it plays in the maternal vascular adaptation to pregnancy.
Supplementary Materials: Additional files from Phylogenetic and functional evidence suggests that deep-ocean ecosystems are highly sensitive to environmental change and direct human disturbance.
Creators: name: Ashford, Oliver S.
name: Kenny, Andrew J.
name: Froján, Christopher R. S. Barrio
name: Bonsall, Michael B.
name: Horton, Tammy
name: Brandt, Angelika
name: Bird, Graham J.
name: Gerken, Sarah
name: Rogers, Alex D.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences

description: An understanding of the balance of interspecific competition and the physical environment in structuring organismal communities is crucial because those communities structured primarily by their physical environment typically exhibit greater sensitivity to environmental change than those structured predominantly by competitive interactions. Here, using detailed phylogenetic and functional information, we investigate this question in macrofaunal assemblages from Northwest Atlantic Ocean continental slopes, a high seas region projected to experience substantial environmental change through the current century. We demonstrate assemblages to be both phylogenetically and functionally under-dispersed and thus conclude that the physical environment, not competition, may dominate in structuring deep-ocean communities. Further, we find temperature and bottom trawling intensity to be amongst the environmental factors significantly related to assemblage diversity. These results hint that deep-ocean communities are highly sensitive to their physical environment and vulnerable to environmental perturbation, including by direct disturbance through fishing, and indirectly through the changes brought about by climate change.
Impact des microorganismes sur le comportement des matériaux biosourcés : dénombrement, caractérisations mécaniques et thermiques
Creators: name: EL HAJJAR, Mohamad
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: L’objectif de cette recherche est d’évaluer l’impact du développement des microorganismes sur le comportement des matériaux biosourcés destinés à l’isolation thermique des bâtiments. L’étude s’intéresse plus particulièrement à deux biocomposites avec deux formulations différentes à base de paille de blé, de chaux préformulée Tradical PF70, et des additifs issus de biomasses animales. Un dénombrement des microorganismes, avec deux milieux de culture différents, a été réalisé sur ces matériaux après un vieillissement accéléré pendant 6 mois dans des conditions favorisant le développement microbien. Les propriétés mécaniques et thermiques ont été étudiées après l’exposition des échantillons aux conditions de vieillissement permettant d’évaluer l’impact du développement microbien. Ce développement a dégradé les propriétés fonctionnelles d’un des deux matériaux, contenant des biomasses naturelles qui ont favorisé ce développement microbien.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
Mesure du gonflement-retrait des granulats végétaux par analyse d’image
Creators: name: Achour, Chafic
name: Remond, Sebastien
name: Belayachi, Naima
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: Le présent travail vise à étudier le gonflement et le retrait des granulats végétaux utilisés pour le développement des matériaux isolants pour le bâtiment. Un protocole expérimental a été adopté avec un cycle d’humidité relative comportant différents paliers permettant un comportement de gonflement-retrait de ces granulats très sensibles à l’humidité et au contact de l’eau. Le but ici, est d’estimer le pourcentage de gonflement/retrait résultant de ces variations dimensionnelles causées par les cycles d’humidification séchage. Après chaque palier, une analyse d’image est réalisée par un microscope optique pour mesurer la dilatation des granulats. Le rapport résultant entre la variation dimensionnelle d'un échantillon et celle de sa masse (due à l'absorption ou désorption de l’eau/vapeur d’eau) est désigné par le coefficient d'expansion ou rétraction hygroscopique β. Les résultats montrent un gonflement important et un comportement qui n'est pas réversible, présentant une hystérésis notable.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
Probing the magnitude of asymmetries in the lateral density distribution of electrons in EAS
Creators: name: Basak, Animesh
name: Dey, Rajat K.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The lateral density distributions (LDD) of inclined cosmic ray air shower are asymmetric and the corresponding iso-density contours are of increasing eccentric ellipses with zenith angles of different showers. The polar asymmetry of the iso-density contours introduces a significant shift of the EAS core, which is quantitatively expressed as a gap length (GL) parameter between the EAS core and the center of the modified density pattern consisting of several equi-density ellipses. The LDD of EAS particles is usually approximated by a particular type of lateral density function (LDF) which is generally assumed to be polar symmetric about the EAS axis, and cannot describe the asymmetric LDDs accurately. A polar angle-dependent modified lateral density function of EASs has been derived analytically by considering the effect of attenuation of EAS particles in the atmosphere. From the simulation studies, it has been found that the GL manifests sensitivity to the cosmic ray mass composition. The cosmic ray mass sensitivity of the lateral shower age is also re-examined by applying the modified LDF to the simulated data.
description: 4 pages, 13 figures,Submitted for publication in J. Phys. (CS)
Plateforme de recyclage de déchets inertes du BTP : un puits de carbone « gris » ?
Creators: name: Hou, Yunlu
name: Mahieux, Pierre-Yves
name: Turcry, Philippe
name: Lux, Jerôme
name: Aït-Mokhtar, Abdelkarim
name: Nicolaï, Aurélia
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: Dans un environnement urbain, les pièges à carbone naturels et artificiels peuvent être des leviers intéressants pour tendre vers la neutralité carbone d’un territoire. Cette étude s’intéresse au potentiel de piégeage de CO2 d’un stock de granulats recyclés, fabriqués sur une plateforme de recyclage à partir de déchets inertes du BTP, entre deux campagnes de concassage. Grâce au développement d’une cellule de carbonatation naturelle et d’une cellule de diffusion de O2 en laboratoire, la quantité de CO2 piégé par un stock de 2000 m3 pendant 4 mois est estimée à plus de 630 kg, soit 0,2 kg de CO2/t de GR en stock. Cette faible valeur montre que même si le potentiel de piégeage de CO2 à l’échelle du grain est estimé à 23 kgCO2/t de GR, la capacité réelle d’un stock de GR à en piéger en condition atmosphérique est très dépendante du process de fabrication, du stockage sur plateforme et des conditions météorologiques.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
(2062) Mary [Beswick]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 1 of IITA’s genebank, cowpea diversity on farms, and farmers’ welfare in Nigeria
Creators: name: Kouakou, Abel-Gautier
name: Ogundapo, Ademola
name: Smale, Melinda
name: Jamora, Nelissa
name: Manda, Julius
name: Abberton, Michael
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Land area harvested (ha) and production quantity (tons) of cowpea in Nigeria (1980–2020). Fig. S2. Diagrams of adopted improved cowpea varieties pedigree trees.
Fluage du béton et du béton précontraint à 20°C et 40°C
Creators: name: Cagnon, Hugo
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: Cette étude a été réalisée dans le cadre du projet ANR PIA MACENA portant sur le comportement mécanique d’une enceinte de confinement des centrales nucléaires françaises en cas d'accident. Le chauffage d'un béton sous charge peut induire une déformation thermique transitoire qui se caractérise par de fortes cinétiques et amplitudes. En cas d’accident, les augmentations de pression interne et de température entraîneraientt des redistributions de contraintes et des diminutions des forces de précontrainte non négligeables dont les répercussions en termes de pertes potentielles d’étanchéité de l'enceinte de confinement doivent être évaluées. L’objectif de cette étude est de fournir des données expérimentales de retrait et fluage en situation d’accident. Les résultats doivent permettre de mieux comprendre les mécanismes de la déformation thermique transitoire afin d’améliorer les modèles de fluage.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
(2057) Richard Thomas Greenland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Effects of risperidone on auditory event-related potentials in schizophrenia
Creators: name: Bates, John
name: Lieberman, Jeffrey
name: Kane, John
name: Umbricht, Daniel
name: Pollack, Simcha
name: Javitt, Daniel
name: Novak, Gerald
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: Schizophrenia is associated with cognitive deficits for which treatments remain elusive. The effects of risperidone (an antipsychotic differing in some of its pharmacological properties from typical agents) on cognitive deficits have not been extensively investigated. Mismatch negativity (MMN), N2 and P3 are cognitive event-related potentials that index preattentive (MMN) and attention-dependent information processing (N2, P3) and provide a measure of cognitive deficits in schizophrenia. The effects of risperidone treatment on MMN, N2 and P3 generation in chronic schizophrenic patients were investigated in an open- label, uncontrolled study. Risperidone treatment significantly reduced psychotic symptoms. It was associated with a decrease of peak latencies, particularly pronounced for P3. However, it did not significantly affect abnormal MMNor P3 amplitudes. The results suggest an effect of risperidone on processing speed, particularly in attention-dependent tasks. These results are in agreement with findings in recent studies on the cognitive effects of risperidone.
Valorisation de déchets de polyuréthane dans des mortiers
Creators: name: Salem, Thouraya
name: Shehadeh, Danah
name: Bouchenafa, Othmane
name: Florence, Céline
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: La valorisation des déchets recyclables dans les matériaux cimentaires favorise l’écoconstruction. Elle permet d’éviter l’épuisement des ressources naturelles tout en donnant une nouvelle vie aux déchets recyclables qui se trouvent en grande quantité tel que le polyuréthane (PU). Ce travail étudie la faisabilité d’incorporation du PU sous forme de granulé (PUG) dans un mortier cimentaire. Les propriétés du mortier de PUG à l’état frais (teneur en air occlus, masse volumique, affaissement) et à l’état durci (résistance à la flexion et à la compression) sont comparées à un mortier normalisé. Les résultats obtenus montrent la nécessité d’utilisation de 1,5% en masse du ciment de superplastifiant pour une meilleure ouvrabilité du mortier incorporant 5% en masse de PUG. Pour ce taux d’incorporation, une diminution de 6% de la masse volumique à l’état frais, de 42% de la résistance à la compression et de 30% de la résistance à la flexion a été obtenue en raison notamment de la légèreté et de la fragilité du PUG comparé au sable.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
(2059) William Horatio Nelson Myers
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Discovery of Novel, Selective, and Nonbasic Agonists for the Kappa-Opioid Receptor Determined by Salvinorin A-Based Virtual Screening
Creators: name: Puls, Kristina
name: Olivé-Marti, Aina-Leonor
name: Hongnak, Siriwat
name: Lamp, David
name: Spetea, Mariana
name: Wolber, Gerhard
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: human diseases
subject: treatment
subject: kappa-opioid receptor
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik

description: Modulating the kappa-opioid receptor (KOR) is a promising strategy for treating various human diseases. KOR agonists show potential for treating pain, pruritus, and epilepsy, while KOR antagonists show potential for treating depression, anxiety, and addiction. The diterpenoid Salvinorin A (SalA), a secondary metabolite of Salvia divinorum, is a potent and selective KOR agonist. Unlike typical opioids, SalA lacks a basic nitrogen, which encouraged us to search for nonbasic KOR ligands. Through structure-based virtual screening using 3D pharmacophore models based on the binding mode of SalA, we identified novel, nonbasic, potent, and selective KOR agonists. In vitro studies confirmed two virtual hits, SalA-VS-07 and SalA-VS-08, as highly selective for the KOR and showing G protein-biased KOR agonist activity. Both KOR ligands share a novel spiro-moiety and a nonbasic scaffold. Our findings provide novel starting points for developing therapeutics aimed at treating pain and other conditions in which KOR is a central player.
TASG – An integrated method for the aerodynamic design of HLFC
Creators: name: Kilian, Thomas
name: Wedler, Sven
Publisher: name: Zenodo
Year: 2020
Subjects: hybird laminar flow control, TASG, aerodynamic design, transition analysis

description: In order to ease the hybrid laminar flow control design, the essential methods for the aerodynamic design of hybrid laminar flow control systems and the transition analysis are integrated in design tool TASG. Using different application scenarios from research and industry the working environment and the different functionalities of the TASG tool are explained.
description: Acknowledgement: This project has received funding from the Clean Sky 2 Joint Undertaking (JU) under grant agreement No 945583. The JU receives support from the European Union's Horizon 2020 research and innovation programme and the Clean Sky 2 JU members other than the Union. Disclaimer: The results, opinions, conclusions, etc. presented in this work are those of the author(s) only and do not necessarily represent the position of the JU; the JU is not responsible for any use made of the information contained herein.
Additional file 1 of Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes
Creators: name: Chen, Baobao
name: Deng, Mingtian
name: Pan, Meng-Hao
name: Sun, Shao-Chen
name: Liu, Honglin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Phenotype of zygotes following treatment with inhibitors of MEK1/2, ERK1/2, p38, and JNK. Figure S2. The expression of phosphorylated and total MAPKs proteins in zygotes treated with corresponding inhibitors. Figure S3. The expression of pluripotent genes in morula that zygotic ERK1/2 inhibited. Figure S4. The expression of Dnmt1 and Dnmt3a in DNMT-inhibited zygotes.
(2060) Mary Elizabeth Beswick
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Table S2 from On the role of sex differences for evolution in heterogeneous and changing fitness landscapes: insights from pygmy grasshoppers
Creators: name: Forsman, Anders
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Developmental Biology
subject: 60801 Animal Behaviour

description: Genetic structure of outlier genetic loci in Tetrix undulata according to sampling location and sex
title: Mobile Identitäten
title: Praktiken und Diskurse der Eliten von Blumenau, Brasilien (1929–1950)
titleType: Subtitle
Creators: name: Frotscher, Méri
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Deutsche Auswanderung
subject: Blumenau
subject: Brasilien
subject: Identitätsdiskurse
subject: Ethnizität
subject: Politik
subject: Eliten
subject: Öffentlichkeit
subject: Kolonialisierung
subject: 900 Geschichte und Geografie::980 Geschichte Südamerikas::980 Geschichte Südamerikas

description: Das südbrasilianische Blumenau, gegründet als Privatkolonie durch den Chemiker Hermann Blumenau, galt in deutschen Kolonialdiskursen als Beispiel für ein erfolgreiches Kolonisierungsprojekt in Übersee und in brasilianischen Kreisen als „deutscher“ Ort. Während des Estado Novo (1937–1945) wurde es von der Regierung, der Armee und einem Teil der brasilianischen Intellektuellen als Grenzgebiet der Nation betrachtet. Aus diesem Grund war es eines der Hauptziele der Nationalisierungspolitik für Einwanderer und ihre Nachkommen. Die Unterdrückung, die Verbote und die Einführung von Praktiken, die darauf abzielten, die „Brasilianität“ aufzubauen, wirkten sich auf das kulturelle und politische Leben in der Gemeinde aus. Ziel des Buches ist es, die Veränderungen und Kontinuitäten in den Identitätsdiskursen der Bevölkerung von Blumenau zwischen zwei Gedenkfeiern zu untersuchen: dem hundertsten Jahrestag der deutschen Einwanderung nach Santa Catarina (1929) und dem der Gründung der Kolonie Blumenau (1950). Die Autorin zeigt die enge Beziehung zwischen Kultur und Politik und beleuchtet die Akteure, Reaktionen, Aushandlungen, Widerstände und Anpassungen der lokalen Eliten in der Zeit des Vargismus (1930–1945) und des Zweiten Weltkriegs sowie die Auswirkungen auf die Neuformulierung von Identitätsdiskursen. Wie das Buch zeigt, war der Diskurs, der Blumenau 1929 als „engere Heimat“ in Brasilien oder sogar als „Musterkolonie“ dank der Aufrechterhaltung des Deutschtums darstellte, nach dem Ende des Krieges und des Estado Novo-Regimes in der Öffentlichkeit tabu. 1950, im Kontext der Demokratisierung, verteidigten einige Mitglieder der lokalen Eliten das Recht auf kulturelle Besonderheiten und betrachteten die „Pluralität der Kultur“ als Faktor für wirtschaftlichen Fortschritt, während sie gleichzeitig die „Brasilianität“ der Stadt bekräftigten. Der verbotene Diskurs über die Überlegenheit der „deutschen“ Arbeit wurde angepasst, indem die Rolle der europäischen Einwanderer bei der Industrialisierung von Blumenau und des Itajaí-Tals betont wurde.
Etude probabiliste et de robustesse d’une structure en bois du patrimoine historique
Creators: name: TEVI, Komlan Renaud
name: ELACHACHI, Sidi Mohammed
name: COINTE, Alain
name: MAURIN, Emmanuel
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: La sécurité d’une structure existante en bois dépend aussi de sa capacité à redistribuer les efforts subis en cas de dégradations/dommages localisés. Cette capacité est désignée par le terme de robustesse. Plusieurs indicateurs existent dans la littérature pour définir la robustesse d’un système structurel. L’objectif de ce travail est d’évaluer la robustesse d’une structure en bois du patrimoine historique à travers une étude probabiliste et fiabiliste en tenant compte des spécificités des structures en bois. Des campagnes expérimentales menées in situ et en laboratoire ont permis d’adopter des distributions probabilistes pour les variables et paramètres implémentés dans un modèle éléments finis simplifié représentatif de la structure. Les résultats ont permis d’identifier les assemblages les plus importants sur le plan de la robustesse de la structure.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
Chromium treatment of depression
Creators: name: Golden, Robert N.
name: McLeod, Malcolm N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Eight patients with refractory mood disorders received chromium supplements and described dramatic improvements in their symptoms and functioning. In several instances, single-blind trials confirmed specificity of response to chromium. Side-effects were rare and mild, and most commonly included enhanced dreaming and mild psychomotor activation. To our knowledge, this is the first case series describing the response to chromium monotherapy. The putative antidepressant effects of chromium could be accounted for by enhancement of insulin utilization and related increases in tryptophan availability in the central nervous system, and/or by chromium's effects on norepinephrine release.
Mental improvement after replacement therapy with thyroxine plus triiodothyronine: relationship to cause of hypothyroidism
Creators: name: Bunevicius, Robertas
name: Prange Jr., Arthur J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: We treated 26 hypothyroid women - 11 with autoimmune thyroiditis and 15 who had been treated for thyroid cancer - with their usual dose of thyroxine (T4) or with a regimen in which 50 &mgr;g of T4 had been replaced by 12.5 &mgr;g of triiodothyronine (T3). Patients were first randomly assigned to one regimen for 5 wk and then to a second regimen for an additional 5 wk. The substitution of T3 for a portion of T4 caused expected changes in concentrations of thyroid hormones and thyroid-stimulating hormone (TSH). After combined hormone treatment there were clear improvements in both cognition and mood, the latter changes being greater. The patients who had been treated for thyroid cancer showed more mental improvement than the women with autoimmune thyroiditis, perhaps because they were more dependent on exogenous hormone. Some mood improvements correlated positively with changes in TSH while others correlated negatively with changes in free T4.
Additional file 2 of Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes
Creators: name: Chen, Baobao
name: Deng, Mingtian
name: Pan, Meng-Hao
name: Sun, Shao-Chen
name: Liu, Honglin
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Table S1. Primers used for qRT-PCR analysis.
title: Erziehung, Religion und ethnische Identität
title: Die Allgemeine Lehrerzeitung und das deutsch-evangelische Schulwesen in Rio Grande do Sul, Brasilien (1902–1938); übersetzt von Raquel Meneguzzo
titleType: Subtitle
Creators: name: Arendt, Isabel Cristina
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Migration
subject: Brasilien
subject: Presse
subject: Identität
subject: Schulen
subject: Protestantismus
subject: Vereinswesen
subject: Deutschtum
subject: Deutschtumspolitik
subject: Nationalsozialismus
subject: 900 Geschichte und Geografie::980 Geschichte Südamerikas::980 Geschichte Südamerikas

description: Bei der vorliegenden Studie handelt es sich um eine kulturwissenschaftliche Doktorarbeit, die an der Universität Vale do Rio dos Sinos (UNISINOS) in São Leopoldo im brasilianischen Bundesstaat Rio Grande do Sul verteidigt wurde. Zentrales Thema sind die Repräsentationen und Debatten über Deutschtum, Schule und Lehrer in der Allgemeinen Lehrerzeitung für Rio Grande do Sul, dem Vereinsblatt des Deutschen Evangelischen Lehrervereins in Rio Grande do Sul, das zwischen 1902 und 1938 monatlich erschien. Die Zeitschrift ist eine wichtige Quelle für die Geschichte der deutschsprachigen Presse in Brasilien und für die Geschichte des brasilianischen Bildungswesens. Darüber hinaus besteht eine Beziehung zur deutschen Geschichte, da die Redakteure und Autoren der Lehrerzeitung, von denen die meisten Deutschlehrer waren, Darstellungen des Deutschtums, der Schule und des Lehrers konstruierten, die deutsche Identität vor Ort verwalteten, Verhaltensregeln aufstellten und Lektüreempfehlungen für Lehrer gaben, die an den sogenannten deutsch-brasilianischen evangelisch-lutherischen Schulen arbeiteten, die die Hauptleserschaft der Zeitschrift bildeten. Die Studie diskutiert auch die Rolle der Schule für die brasilianische Nationalisierungspolitik und den Nationalsozialismus. Im Mittelpunkt stehen Verhandlungsstrategien, die sich in der Zeitschrift finden lassen, um das deutsch-evangelische Privatschulwesen aufrechtzuerhalten, das die Förderung des Deutschtums und die Erziehung zu brasilianischen Staatsbürgern zum Ziel hatte. Auch die Beziehung zwischen dem Deutschen Evangelischen Lehrerverein und der Riograndenser Synode, die damals eine der wichtigsten Stützen des Deutschtums war, wird erörtert.
Variability-aware modeling of electrochemical metallization memory cells
Creators: name: Ahmad, Rana Walied
name: Waser, Rainer
name: Maudet, Florian
name: Toprak, Onur
name: Dubourdieu, Catherine
name: Menzel, Stephan
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: memristive devices
subject: variability-aware modeling
subject: ReRAM
subject: ECM
subject: CBRAM
subject: SPICE level
subject: compact model
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Resistively switching electrochemical metallization memory cells are gaining huge interest since they are seen as promising candidates and basic building blocks for future computation-in-memory applications. However, especially filamentary-based memristive devices suffer from inherent variability, originating from their stochastic switching behavior. A variability-aware compact model of electrochemical metallization memory cells is presented in this study and verified by showing a fit to experimental data. It is an extension of the deterministic model. Since this extension consists of several different features allowing for a realistic variability-aware fit, it depicts a unique model comprising physics-based, stochastically and experimentally originating variabilities and reproduces them well. In addition, a physics-based model parameter study is executed, which enables a comprehensive view into the device physics and presents guidelines for the compact model fitting procedure.
Hygro-thermal properties of raw earth building material
Creators: name: HAMROUNI, Ichrak
name: Ouahbi, Tariq
name: Taibi, Said
name: Jemai, Mehrez
name: Zenzri, Hatem
Publisher: name: Academic Journal of Civil Engineering
Year: 2022

description: Raw earth is the oldest building technique used for over 11 centuries thanks to its various benefits. The most known earth construction’s technics are compressed earth blocks, rammed earth, raw earth concrete and daub and it can be stabilized with bio-sourced binders, mixed by fibers or hyper-compacted in order to improve its mechanical behavior. Besides, as many researches have been shown, this ecological material is able to contribute to moisture and heat control in buildings. Its hygrothermal properties are better than fired earth bricks and concrete. The aim of this study is to evaluate the hygrothermal behavior of raw earth material which called “Cematerre”, using experimental tests such as the water vapor permeability and thermal conductivity and numerical simulations of thermal and hygroscopic transfers.
description: Academic Journal of Civil Engineering, Vol 40 No 1 (2022): Special Issue - RUGC 2022
(2058) Mary Greenland
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
An Online Parallel and Distributed Algorithm for Recursive Estimation of Sparse Signals
Creators: name: Yang, Yang
name: Zhang, Mengyi
name: Pesavento, Marius
name: Palomar, Daniel P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In this paper, we consider a recursive estimation problem for linear regression where the signal to be estimated admits a sparse representation and measurement samples are only sequentially available. We propose a convergent parallel estimation scheme that consists in solving a sequence of $\ell_{1}$-regularized least-square problems approximately. The proposed scheme is novel in three aspects: i) all elements of the unknown vector variable are updated in parallel at each time instance, and convergence speed is much faster than state-of-the-art schemes which update the elements sequentially; ii) both the update direction and stepsize of each element have simple closed-form expressions, so the algorithm is suitable for online (real-time) implementation; and iii) the stepsize is designed to accelerate the convergence but it does not suffer from the common trouble of parameter tuning in literature. Both centralized and distributed implementation schemes are discussed. The attractive features of the proposed algorithm are also numerically consolidated.
description: Part of this work has been presented at The Asilomar Conference on Signals, Systems, and Computers, Nov. 2014
Supplementary Materials: Additional files from Phylogenetic and functional evidence suggests that deep-ocean ecosystems are highly sensitive to environmental change and direct human disturbance
Creators: name: Ashford, Oliver S.
name: Kenny, Andrew J.
name: Froján, Christopher R. S. Barrio
name: Bonsall, Michael B.
name: Horton, Tammy
name: Brandt, Angelika
name: Bird, Graham J.
name: Gerken, Sarah
name: Rogers, Alex D.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences

description: An understanding of the balance of interspecific competition and the physical environment in structuring organismal communities is crucial because those communities structured primarily by their physical environment typically exhibit greater sensitivity to environmental change than those structured predominantly by competitive interactions. Here, using detailed phylogenetic and functional information, we investigate this question in macrofaunal assemblages from Northwest Atlantic Ocean continental slopes, a high seas region projected to experience substantial environmental change through the current century. We demonstrate assemblages to be both phylogenetically and functionally under-dispersed and thus conclude that the physical environment, not competition, may dominate in structuring deep-ocean communities. Further, we find temperature and bottom trawling intensity to be amongst the environmental factors significantly related to assemblage diversity. These results hint that deep-ocean communities are highly sensitive to their physical environment and vulnerable to environmental perturbation, including by direct disturbance through fishing, and indirectly through the changes brought about by climate change.