cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Jede Charge elektronisch dokumentiert - Sherlock Holmes sichert Konsumenten
Creators: name: Göckel, Matthias
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2005
Subjects: subject: E-Business
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Die Chargenrückverfolgung zur Gewährleistung einer lückenlosen Dokumentation der Herstellung und Distribution der Produkte bekommt nicht mehr nur in der Pharma- und Lebensmittelindustrie, sondern auch zunehmend in anderen Industriesektoren einen hohen Stellenwert zugesprochen. Bei Muelhens untersuchte man die gegebenen Strukturen, Funktionen und Prozesse um eine effiziente und in allen Prozessschritten transparente Chargenrückverfolgung einzuführen.
Additional file 7 of Identification of a novel ERF gene, TaERF8, associated with plant height and yield in wheat
Creators: name: Zhang, Lei
name: Liu, Pan
name: Wu, Jing
name: Linyi Qiao
name: Guangyao Zhao
name: Jizeng Jia
name: Lifeng Gao
name: Jianming Wang
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 7: Table S5. The information of sample set 2 and their genotypes of TaERF8-2B.
Management of a Virtual Community of Students
Creators: name: Dettling, Walter
name: Schubert, Petra
Publisher: name: Routledge
Year: 2002
Subjects: subject: Virtual Communities
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Since its inception, the internet has served as a virtual meeting place for people sharing common interests. These interest groups are nowadays called Virtual Communities. In this paper we elaborate the concept of a Virtual Community of Students (vicos) who consists of different interest groups in and around Swiss Universities of Applied Sciences (UAS). Vicos is a hybrid form of a community: it combines aspects of a Learning Community as well as of a Business Community. We describe the findings of a comprehensive empirical study which addressed the main target group (the students) and which resulted into the basic concept of vicos. The key contribution of this paper is the linkage between the conceptual community design of vicos and the business model, which is needed to successfully operate vicos as a sustainable internet platform. We conclude with a description of future steps for vicos.Mehr zum JMM - The International Journal on Media Management.
The association between leucocyte telomere length and Acute Myocardial Infarction (AMI) and its prognostic value in predicting the thirty-days and six-months outcomes post-AMI: A single centre study
Creators: name: Jong, Siu Mei
Publisher: name: Swinburne
Year: 2024

description: Telomeres are DNA protein complexes at the ends of our chromosomes believed to protect the genetic data from being loss during cell division. The thesis describes whether these telomeres are predictors of the Acute Myocardial Infarction (AMI) clinical outcomes in a Malaysian cohort, and to assess the rate of change in the telomere length over time. Results from this research have added to the knowledge of the clinical management of the AMI patients. A predictor scoring system called the TELAMI score has been defined via this research which determines the risks of mortality and readmissions of the AMI patients.
Morphologies of z ~ 0.7 AGN host galaxies in CANDELS: No trend of merger incidence with AGN luminosity
Creators: name: Villforth, C.
name: Hamann, F.
name: Rosario, D. J.
name: Santini, P.
name: McGrath, E. J.
name: Wel, A. v. d.
name: Chang, Y. Y.
name: Guo, Y.
name: Dahlen, T.
name: Bell, E. F.
name: Conselice, C. J.
name: Croton, Darren
name: Dekel, A.
name: Faber, S. M.
name: Grogin, N.
name: Hamilton, T.
name: Hopkins, P. F.
name: Juneau, S.
name: Kartaltepe, J.
name: Kocevski, D.
name: Koekemoer, A.
name: Koo, D. C.
name: Lotz, J.
name: McIntosh, D.
name: Mozena, M.
name: Somerville, R.
name: Wild, V.
Publisher: name: Swinburne
Year: 2024

description: The processes that trigger active galactic nuclei (AGN) remain poorly understood. While lower luminosity AGN may be triggered by minor disturbances to the host galaxy, stronger disturbances are likely required to trigger luminous AGN. Major wet mergers of galaxies are ideal environments for AGN triggering since they provide large gas supplies and galaxy scale torques. There is however little observational evidence for a strong connection between AGN and major mergers. We analyse the morphological properties of AGN host galaxies as a function of AGN and host galaxy luminosity and compare them to a carefully matched sample of control galaxies. AGN are X-ray selected in the redshift range 0.5 < z < 0.8 and have luminosities 41 < log(LX [erg s-1]) < 44.5. 'Fake AGN' are simulated in the control galaxies by adding point sources with the magnitude of the matched AGN. We find that AGN host and control galaxies have comparable asymmetries, Sersic indices and ellipticities at rest frame 50 nm. AGN host galaxies show neither higher average asymmetries nor higher fractions of very disturbed objects. There is no increase in the prevalence of merger signatures with AGN luminosity. At 95 per cent confidence we find that major mergers are responsible for <6 per cent of all AGN in our sample as well as <40 per cent of the highest luminosity AGN (log (LX [erg s-1]) 43.5). Major mergers therefore either play only a very minor role in the triggering of AGN in the luminosity range studied or time delays are too long for merger features to remain visible.
Knowledge Transfer from Researchers to Businesses - eXperience and EUREXIS
Creators: name: Sigrist, Barbara
name: Göckel, Matthias
name: Schubert, Petra
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2004
Subjects: subject: Case Study
subject: CMS
subject: Collaboration
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Researchers depend upon business people and vice versa. They profit from each other by means of knowledge exchange: business of all sizes learn by reading about successful and unsuccessful projects and researchers gain insights through sophisticated research activities around aggregated case studies. There are various efforts in Europe directed to support these activities, of which two are discussed in this paper. eXperience is a Swiss project aimed at Swiss researchers and businesses deploying an operational case study platform. EUREXIS is an international Network of Excellence combining research agendas with local businesses and research institutions in Europe. Both projects build upon a common understanding of the e domain: the e business navigator. The e-business navigator is an approach for a common terminology that serves the specific purpose to foster structured storage and accessibility of knowledge about e-business best practice.
Facilitated Peptide Transport via the Mucosal Epithelium
Creators: name: Kenngott, Elisabeth E.
name: Pfeil, Jennifer
name: Hoffmann, Ute
name: Lauer, Uta
name: Kuehl, Anja A.
name: Rigby, Anne
name: Pernthaner, Anton
name: Hamann, Alf
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: oral tolerance
subject: peptide vaccination
subject: targeted delivery
subject: mucosa
subject: regulatory T cells
subject: mucosal uptake
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: A hallmark of autoimmunity is the breakdown of tolerance and generation of effector responses against self-antigens. Re-establishment of tolerance in autoimmune disorders was always the most desired treatment option; however, despite many efforts, clinical trials have been largely unsuccessful. This also applies to the generation of oral tolerance, which seems to be a default response type of the mucosa-associated lymphoid tissues to harmless antigens. In this study, we report improved efficacy of oral tolerance induction by coupling antigen with the newly identified mucosal carrier peptide 13C. Antigen coupled to 13C is efficiently taken up in the gastrointestinal tract and could be visualized in cells of the lamina propria. Oral, rectal, or nasal treatment effectively induced the proliferation of antigen-specific T cells with some increase in the frequency of regulatory T cells. In a model of delayed-type hypersensitivity, especially intrarectal tolerization treatment resulted in reduced footpad swelling, demonstrating a moderate tolerogenic effect of mucosal treatment with 13C coupled antigen. Coupling of antigens to a transmucosal carrier, therefore, is a promising tool to improve the efficacy of vaccination via mucosal surfaces.
Narratives of Privilege: An Ethnographic Study of Colombian-Born Women Living in Melbourne, Australia
Creators: name: Adler, Viktoria
Publisher: name: Swinburne
Year: 2024

description: This thesis examines how white, and middle or upper class female migrants from Colombia experience their privilege living in Melbourne, Australia. The research shows how privilege travels with these women. Nonetheless, their privilege changes as it is contextual. The women are able to profit from some aspects of their privilege, they lose others and gain new ones. This ethnographic research contributes to the literature on intersectionality and adds to the scare scholarship on privileged female migrants from the Global South.
Proceedings of the Ninth Research Symposium on Emerging Electronic Markets 2002
Creators: name: Schubert, Petra
name: Leimstoll, Uwe
Publisher: name: Fachhochschule beider Basel (FHBB), Institute for Business Economics, Basel, Switzerland
Year: 2002
Subjects: subject: E-Business
subject: Electronic Markets
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Background of the Ninth Research Symposium on Emerging Electronic Markets (RSEEM)The Research Symposium on Emerging Electronic Markets (RSEEM) is an annual event destined to provide a forum for researchers for presentation and discussion of their current and ongoing work. In order to stimulate a lively discussion, the number of participants has traditionally been limited to 30 people. In 2002, we had two focus topics:E-Procurement and the Future of Electronic MarketsCompared to recent years, we wanted to further extend time for discussion. The forum serves two purposes. First of all it provides a platform for doctoral students to present their ideas and receive feedback from an international audience. Ongoing Ph.D. theses and projects are presented by junior researchers and input is given by the other participants. Besides, we asked for short presentations of visions of the future followed by a moderated discussion among the participants.
Design of Material Microstructures with Functional Properties through Topology Optimization
Creators: name: Chen, Weijian
Publisher: name: Swinburne
Year: 2024

description: By designing the material microstructures, enhanced performance or novel properties of the materials can be achieved. Different from the traditional design approach, topology optimization offers a more systematic and intelligent approach to optimally achieve the desired and exotic properties. It has demonstrated great potentials for material design by combining with the homogenization theory. This thesis has developed the inverse design of elastoplastic materials and chiral structures and materials through topology optimization. A variety of novel materials have been successfully obtained. The developed topology optimization algorithms open the door to explore other exotic properties of materials in the future.
title: Cardiac Fibroblasts Aggravate Viral Myocarditis
title: Cell Specific Coxsackievirus B3 Replication
titleType: Subtitle
Creators: name: Lindner, Diana
name: Li, Jia
name: Savvatis, Konstantinos
name: Klingel, Karin
name: Blankenberg, Stefan
name: Tschöpe, Carsten
name: Westermann, Dirk
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Myocarditis is an inflammatory disease caused by viral infection. Different subpopulations of leukocytes enter the cardiac tissue and lead to severe cardiac inflammation associated with myocyte loss and remodeling. Here, we study possible cell sources for viral replication using three compartments of the heart: fibroblasts, cardiomyocytes, and macrophages. We infected C57BL/6j mice with Coxsackievirus B3 (CVB3) and detected increased gene expression of anti-inflammatory and antiviral cytokines in the heart. Subsequently, we infected cardiac fibroblasts, cardiomyocytes, and macrophages with CVB3. Due to viral infection, the expression of TNF-α, IL-6, MCP-1, and IFN-β was significantly increased in cardiac fibroblasts compared to cardiomyocytes or macrophages. We found that in addition to cardiomyocytes cardiac fibroblasts were infected by CVB3 and displayed a higher virus replication (132-fold increase) compared to cardiomyocytes (14-fold increase) between 6 and 24 hours after infection. At higher virus concentrations, macrophages are able to reduce the viral copy number. At low virus concentration a persistent virus infection was determined. Therefore, we suggest that cardiac fibroblasts play an important role in the pathology of CVB3-induced myocarditis and are another important contributor of virus replication aggravating myocarditis.
Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice
Creators: name: Krüger, Janine
name: Brachs, Sebastian
name: Trappiel, Manuela
name: Kintscher, Ulrich
name: Meyborg, Heike
name: Wellnhofer, Ernst
name: Thöne-Reineke, Christa
name: Stawowy, Philipp
name: Östman, Arne
name: Birkenfeld, Andreas L.
name: Böhmer, Frank D.
name: Kappert, Kai
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: Density-enhanced phosphatase-1
subject: Glucose homeostasis
subject: Insulin signaling
subject: Insulin resistance
subject: Phosphorylation
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft

description: Insulin resistance can be triggered by enhanced dephosphorylation of the insulin receptor or downstream components in the insulin signaling cascade through protein tyrosine phosphatases (PTPs). Downregulating density-enhanced phosphatase-1 (DEP-1) resulted in an improved metabolic status in previous analyses. This phenotype was primarily caused by hepatic DEP-1 reduction. Here we further elucidated the role of DEP-1 in glucose homeostasis by employing a conventional knockout model to explore the specific contribution of DEP-1 in metabolic tissues. Ptprj (-/-) (DEP-1 deficient) and wild-type C57BL/6 mice were fed a low-fat or high-fat diet. Metabolic phenotyping was combined with analyses of phosphorylation patterns of insulin signaling components. Additionally, experiments with skeletal muscle cells and muscle tissue were performed to assess the role of DEP-1 for glucose uptake. High-fat diet fed- Ptprj (-/-) mice displayed enhanced insulin sensitivity and improved glucose tolerance. Furthermore, leptin levels and blood pressure were reduced in Ptprj (-/-) mice. DEP-1 deficiency resulted in increased phosphorylation of components of the insulin signaling cascade in liver, skeletal muscle and adipose tissue after insulin challenge. The beneficial effect on glucose homeostasis in vivo was corroborated by increased glucose uptake in skeletal muscle cells in which DEP-1 was downregulated, and in skeletal muscle of Ptprj (-/-) mice. Together, these data establish DEP-1 as novel negative regulator of insulin signaling.
Neutrino oscillation analysis using T2K data with additional single ring NCπ⁰ samples
Creators: name: Martin, Daniel
Publisher: name: Imperial College London
Year: 2024

description: This thesis presents work done as part of the T2K and SK collaborations to perform an in-situ reconstruction of PMT locations in Super-K and the addition of single ring and two ring NCπ0 event samples to the T2K oscillation analysis. Photos taken by drone in Super-K were segmented using machine learning algorithms to identify and reconstruct PMT positions. Feature recognition of PMTs is shown to be viable, though it proved difficult to uniquely identify PMTs for reconstruction. Markov Chain Monte-Carlo techniques were used as part of the MaCh3 software framework to per- form an oscillation analysis with new NCπ⁰ samples using run 1-10 T2K data representing 19.664×10^20 POT in FHC and 16.346×10^20 POT in RHC. The dominant background to single ring electron-like ν_e appearance samples at Super-K is NCπ⁰ events. The new NCπ0 samples aim to constrain the back- ground such that additional oscillated ν_e events can be exploited for increased sensitivity in oscillation fits. Super-K detector systematic uncertainties were updated to include the NCπ⁰ samples with a new atmospheric neutrino fit, resulting in larger systematic uncertainties than previous analyses. An oscillation fit with new NCπ⁰ samples and Super-K detector systematics gives credible intervals of: sin²(θ_13) =[0.0185, 0.0417], sin²(θ_23) =[0.44, 0.58], ∆m²_23 =NO:[2.4, 2.6] IO:[-2.6, -2.4], and δ_CP =[-π, -0.251] [2.551, π] to 2σ confidence. With the application of an additional sin²(θ_13) constraint from reactor neutrino experiments, the intervals are: sin²(θ_23) =[0.45, 0.58], ∆m²_ 23 =NO: [2.4, 2.6] IO: [-2.6, -2.5], and δ_CP =[−π, -0.209] to 2σ confidence. Asimov fits show an additional 3.5% sensitivity to δ_CP with the NCπ⁰ samples added. The credible intervals are in agreement with previous T2K analyses and no further constraint to δ_CP is found. A slightly stronger preference for normal mass ordering, upper sin²(θ_23) octant is observed compared to T2K with 62.1% posterior probability.
Cholesteryl ester transfer protein (CETP) I405V polymorphism and cardiovascular disease in eastern European Caucasians – a cross-sectional study
Creators: name: Bustami, Jasmin
name: Sukiasyan, Anna
name: Kupcinskas, Juozas
name: Skieceviciene, Jurgita
name: Iakoubov, Leonid
name: Szwed, Malgorzata
name: Kleinle, Christoph
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Cholesteryl ester transfer protein
subject: Genetic polymorphism
subject: High-density lipoprotein
subject: Single nucleotide polymorphism
subject: Cardio vascular disease
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Methods A cross-sectional study was conducted to genotype 1028 healthy blood donors and 1517 clinically well characterized elderly for CETP I405V. Results We could not find any association of this polymorphism with age for both, males or females, in any of these cohorts (P = 0.71 and P = 0.57, respectively, for males and P = 0.55 and P = 0.88, respectively, for females). In addition, no association with cardiovascular diseases could be observed in the elderly cohort (males OR = 1.12 and females OR = 0.88). In the same cohort, the CETP V405V genotype was associated with significantly enhanced HDL levels (P = 0.03), mostly owing to the female sex (P = 0.46 for males, P = 0.02 for females), whereas LDL and triglyceride levels were unchanged (P = 0.62 and P = 0.18, respectively). Conclusion Our data support the recent hypothesis that variations enhancing HDL levels without affecting LDL levels are not associated with the risk for cardiovascular diseases.
Alles falsch gemacht beim IT-Outsourcing
Creators: name: Dettling, Walter
Publisher: name: Netzmedien AG
Year: 2004
Subjects: subject: Outsourcing
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Mit IT-Outsourcing-Lösungen kann man nicht gleichzeitig Kosten sparen, die Qualität erhöhen und sich auch noch für zukünftige Entwicklungen alle Optionen freihalten.
Integrierte Verkaufsunterstützung für KMUs
Creators: name: Schubert, Petra
Publisher: name: Netzmedien
Year: 2004
Subjects: subject: B2C
subject: E-Shop
subject: ERP-Systeme
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Mit der Einführung einer E-Shop-Lösung, die nahtlos mit dem ERP-System kommunizieren kann, wurde das B2C-Geschäft von Permashop zum wichtigen Absatzkanal für den Versand von Fanartikeln. Der Shop trägt bereits 60 Prozent zum Versandvolumen bei.
Molecular basis for functional diversification of duplicated hoxb5 genes in zebrafish
Creators: name: Jarinova, Olga
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Biology, Molecular.

description: The Duplication-Degeneration-Complementation (DDC) model predicts that division of the original function between duplicate genes (subfunctionalization) is a common mechanism for their preservation. The Hox genes constitute a good system to test this hypothesis as they underwent significant expansion during evolution. Mammals have four Hox complexes whereas teleosts have additional complexes resulting from duplication event(s) that took place after the separation of the ray-finned and lobe-finned lineages. Thus, zebrafish and Takifugu have two hoxb complexes, each containing a hoxb5 gene. The zebrafish hoxb5a and hoxb5b genes are expressed in overlapping, yet distinct, domains during development with their combined expression patterns similar to that of the single mouse Hoxb5 gene. To determine if changes in cis-acting regulatory elements account for hoxb5a and hoxb5b subfunctionalization, we compared the sequences of the Hoxb5 loci of human, mouse, zebrafish and Takifugu and identified four conserved non-coding elements (CNEs). One of the CNEs, named J3, is only retained in the hoxb5a locus while three others are present in both teleost hoxb5 loci. We examined individual and collective regulatory activity of the CNEs in transgenic assays. When tested individually, the enhancer activity of individual cognate CNEs from the hoxb5a and hoxb5b genes extensively overlapped. In contrast, large fragments encompassing multiple CNEs were able to target reporter gene expression to unique domains of hoxb5a and hoxb5b expression. The deletion of J3 from the hoxb5a locus and its insertion in the hoxb5b locus drastically altered the regulatory activity of the original loci. Our results suggest that patterns of regulatory evolution of hoxb5 duplicates in teleosts may be more complex than ones taken in consideration by the DDC model.
The studies of defence-related transcriptome and potential biocontrol strategies in black pepper (Piper nigrum L.)
Creators: name: Lau, Ee Tiing
Publisher: name: Swinburne
Year: 2024

description: Black pepper is an important commodity crop in Malaysia that generates millions of annual revenue for the country. However, this crop is susceptible to slow decline disease which has caused significance annual yield loss. The current study advance the understanding of black pepper plant defence in response to slow decline and aid in identifying potential solution to manage this disease in black pepper cultivation. Besides that, this study also has proposed biocontrol strategies, an environmental friendly approach as an alternative solution instead of hazardous chemical products in combating slow decline.
กรอบแนวคิดรูปแบบความสัมพันธ์เชิงสาเหตุของปัจจัยที่ส่งผลต่อการพัฒนาองค์กรปกครองส่วนท้องถิ่นสู่การเป็นองค์การที่มีขีดสมรรถนะสูงในประเทศไทย
Creators: name: สุรศักดิ์ ชะมารัมย์
Publisher: name: มหาวิทยาลัยราชภัฏร้อยเอ็ด
Year: 2019
Subjects: ภาวะผู้นำการเปลี่ยนแปลง
วัฒนธรรมองค์การ
โครงสร้างและการออกแบบองค์การ
องค์การที่มีขีดสมรรถนะสูง
องค์กรปกครองส่วนท้องถิ่น

description: วารสารวิชาการและวิจัย มทร.พระนคร สาขามนุษยศาสตร์และสังคมศาสตร์, 4, 1, 102-116
The effects of reduced gill surface area on gas transfer in the rainbow trout (Oncorhynchus mykiss).
Creators: name: Julio, Alejandra E.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Biology, Animal Physiology.

description: The total functional surface area of the gills is a key component in gas exchange and any reduction would predictably limit both oxygen uptake and carbon dioxide excretion. But one might also hypothesise that under these conditions the fish might compensate. A reduction of 15, 30 and 40% of total anatomical gill surface area in rainbow trout was accomplished by the ligation of 1, 2 and 3 gill arches, respectively. With the use of an extracorporeal shunt, arterial blood gases were continuously monitored during normoxia and graded hypoxia. As well, a dorsal aortic cannula allowed for periodic blood sampling for such variables as total arterial oxygen content (CaO2), total arterial carbon dioxide content (CaCO2), haemoglobin concentration, haematocrit and circulating catecholamines. Oxygen uptake (M˙O2), carbon dioxide excretion rates (M˙CO2) and ventilation convection requirements for both gases were determined through measurements of inspired and expired water carbon dioxide content (CCO2) and partial pressure of O2 (PO2) differences as well as in-flowing/out-flowing water CCO2, and PO2 differences. A final series of experiments examined the effects of carbonic anhydrase injections in ligated versus sham-ligated fish as well as comparing these results to ligated fish injected with physiological saline. (Abstract shortened by UMI.)
การเสริมสร้างความเข้มแข็งขององค์การสู่การเป็นองค์การแห่งการเรียนรู้โดยใช้กระบวนการพัฒนาทรัพยากรมนุษย์ในศตวรรษที่ 21
Creators: name: สุรศักดิ์ ชะมารัมย์
Publisher: name: มหาวิทยาลัยราชภัฏร้อยเอ็ด
Year: 2019
Subjects: การพัฒนาทรัพยากรมนุษย์
นักพัฒนาทรัพยากรมนุษย์
องค์การแห่งการเรียนรู้

description: วารสารวิชาการและวิจัย มทร.พระนคร สาขามนุษยศาสตร์และสังคมศาสตร์, 4, 1, 116-131
Changes in competition intensity, herbivory and stress along a soil depth gradient in an old field.
Creators: name: Keogh, Teri M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Biology, Ecology.

description: Four herbaceous plant communities were described along a natural soil depth gradient in an old field. Biomass and canopy height increased with soil depth. Species richness showed a quadratic relationship, whereas the proportion of native species increased with soil depth. The limiting resource was found to be nutrients, not water, even though the year was abnormally dry. I hypothesized that competition was the main factor structuring these communities. The relationship between competition intensity and soil depth was determined through experimentation using two phytometer species, Liatris spicata and Lythrum salicaria. Competition intensity decreased with soil depth across the four communities, which contradicts the Competitor/Stress-Tolerator/Ruderal Hypothesis (CSR) of Grime and Tilman's Resource Ratio hypothesis. Competition in this old field was primarily below ground. Herbivory from large herbivores did not change along the gradient, whereas stress was found to be greatest at both ends of the gradient.
Accelerated hyperfractionation plus temozolomide in glioblastoma
Creators: name: Kaul, David
name: Florange, Julian
name: Badakhshi, Harun
name: Grün, Arne
name: Ghadjar, Pirus
name: Exner, Sebastian
name: Budach, Volker
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Introduction Hyperfractionated (HFRT) or accelerated hyperfractionated radiotherapy (AHFRT) have been discussed as a potential treatment for glioblastoma based on a hypothesized reduction of late radiation injury and prevention of repopulation. HFRT and AHFRT have been examined extensively in the pre-Temozolomide era with inconclusive results. In this study we examined the role of accelerated hyperfractionation in the Temozolomide era. Materials and methods Sixty-four patients who underwent AHFRT (62 of which received Temozolomide) were compared to 67 patients who underwent normofractionated radiotherapy (NFRT) (64 of which received TMZ) between 02/2009 and 10/2014. Follow-up data were analyzed until 01/2015. Results Median progression-free survival (PFS) was 6 months for the entire cohort. For patients treated with NFRT median PFS was 7 months, for patients treated with AHFRT median PFS was 6 months. Median overall survival (OS) was 13 months for all patients. For patients treated with NFRT median OS was 15 months, for patients treated with AHFRT median OS was 10 months. The fractionation regimen was not a predictor of PFS or OS in univariable- or multivariable analysis. There was no difference in acute toxicity profiles between the two treatment groups. Conclusions Univariable and multivariable analysis did not show significant differences between NFRT and AHFRT fractionation regimens in terms of PFS or OS. The benefits are immanent: the regimen does significantly shorten hospitalization time in a patient collective with highly impaired life expectancy. We propose that the role of AHFRT + TMZ should be further examined in future prospective trials.
The historical and theological bases of the Christian religious education program in Ontario public schools.
Creators: name: Perry, Michael L.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Education, History of.

description: This dissertation is a study of the historical and theological bases of the Christian religious education program in the public schools of Ontario. The role of the churches in the introduction, maintenance, decline and disappearance of the program is investigated. In the early years, the Christian Churches in Ontario reflected the religious divisions of Europe following the Reformation. The overwhelming majority of citizens belonged to five major churches, but these were often in conflict with each other over doctrine and vied for government support for their own schools. A system of non-sectarian public schools which provided for optional religious instruction outside of the regular school hours emerged by the middle of the nineteenth century. It was not until the late nineteenth century when Canada was expanding in territory and in population that a movement towards unity in the Protestant churches emerged---partly as a strategy to evangelize the West and partly as a result of like-mindedness in combatting social ills. The union of churches and their increased cooperation in moral and social crusades was a pre-condition for their concerted efforts to obtain increased Christian teaching in the schools. Devotion to a common Bible enhanced these efforts. Under wartime conditions, the Conservative government of George Drew introduced a mandatory program of Christian religious education in the schools in 1944. Supporters of the program thought Christian teaching to be a remedy for various ills: the threats of fascism and communism, juvenile delinquency, sexual promiscuity, moral decline in general. Adherence to the regulations grew lax due to increasing opposition from minority religions and secular groups. The factors which led to the establishment of the program of Christian religious education in 1944 included: reaction to the growth of Roman Catholic separate schools, Protestant ecumenism, concern about juvenile delinquency, the institutional aims of the churches, fears about decline in Sunday School attendance, general concern for the spiritual welfare of children, fears about the growth of secularism and atheism. The factors in the decline of the program relate to the exclusivity, christocentrism, and irrelevance of the Teachers' Guides, but more importantly to the rise of secular attitudes, the indifference of the public to the churches, increased diversity in society, and the basis of minority rights in the Charter of Rights and Freedoms. The program was gradually abandoned and officially dropped in 1990. The factors which led to this development included: the multifaith nature of the society, dated or non-existent curricula and materials, lack of support from society-at-large, the exclusivity of the Christian program, and little interest from teachers and students.
Development and Evaluation of a Precinct Level Low Carbon Mobility Calculator
Creators: name: Moffatt, Damian Luke
Publisher: name: Swinburne
Year: 2024

description: In Australia the third largest source of greenhouse gases is the transport sector (17%) with passenger cars accounting for around half of all transport emissions. This paper presents results from a research project that developed and evaluated a new tool to help decision-makers estimate the carbon footprint of the transport networks within their precincts and municipalities, and to evaluate the reductions from low carbon mobility interventions. The research was developed based on a framework that integrates multiple components including individual travel preferences, traffic simulation, and a calculator interface. A study of Port Phillip Council was also conducted and analysed.
La santé des aînés francophones en situation linguistique minoritaire: État des lieux en Ontario
Creators: name: Bourbonnais, Valérie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Sociology, General.

description: L'objectif de cette thèse est de tracer les profils comparatifs des états de santé des populations francophones et anglophones âgées de 65 ans et plus de l'Ontario en utilisant les données de l'Enquête sur la santé et les collectivités canadiennes (ESCC) recensées par Statistique Canada. Dans un deuxième temps, ces profils seront également analysés en fonction du genre. Or, trois grands volets seront examinés dans ce projet: (1) les caractéristiques socio-démographiques, (2) les états de santé déclarés et perçus, (3) ainsi que l'utilisation et la satisfaction à l'égard des services de soins de santé. L'objectif principal de cette thèse est de démontrer que le fait de vivre dans un contexte linguistique minoritaire engendre des facteurs risquant d'influencer négativement le vieillissement de la minorité sociolinguistique francophone de l'Ontario. En puisant à la discipline sociologique, une théorisation de la minorité sera utilisée afin d'appuyer la thèse avancée. Globalement les analyses révèlent un profil socioéconomique et un profil de santé plus précaires chez les aînés de la minorité francophone comparativement aux aînés de la majorité anglophone. Il est intéressant de noter que cette précarité de la santé s'exprime autant chez les hommes que chez les femmes de la minorité francophone, malgré que celle-ci s'articule différemment pour certaines variables. Quant à la prestation des services de soins de santé, les aînés de la minorité francophone sont unanimement insatisfaits de l'accessibilité, ainsi que de la qualité des services dans l'ensemble de la province ontarienne.
EXPERIMENTAL ANALYSIS OF ION TRANSMISSION IN HIGHER ORDER MATHIEU SPACE STABILITY ZONES USING A DIGITALLY OPERATED QUADRUPOLE MASS FILTER ANALYZER
Creators: name: Chakravorty, Sumeet
Publisher: name: Washington State University
Year: 2025
Subjects: Digital mass filter
Digital waveforms
Mass analyzer
Quadrupoles
Stability zones
Mass Spectrometry

description: Quadrupole mass filters and guides are integral components in many mass spectrometers. These mass filters are typically operated with sinusoidal waveforms applied to the electrodes. In a quadrupole mass filter, opposing electrodes are electrically connected, and each pair receives RF potentials that are 180° out of phase from the other pair. By applying a DC and RF potential, it is possible to narrow the range of stable masses, the stable mass window can be further narrowed by changing the ratio of DC to RF potential and an effective mass filter can be created by ramping both voltages at a fixed frequency. Opposing the conventional technique, mass filters operated with digitally produced waveforms with the frequency varied and the RF and DC potentials fixed can create stable mass windows of variable width by manipulating the duty cycle of the RF waveform on both electrode pairs without applying a static DC potential between the rods. In most analytical techniques, such as the sine-driven mass filter, resolution comes at the cost of transmission or signal intensity. The main advantage of changing the duty cycle is the ability to access narrower stable mass windows in higher order Mathieu space stability zones. At equivalent mass windows and AC voltage, the digitally operated quadrupole theoretically outperforms the traditional sinusoidal quadrupole in terms of the transmission of ions through the mass filter. This work demonstrated the capabilities of digitally operated quadrupole mass filters in their capacity to achieve high resolution and transmission of ions by changing the duty cycle of the RF waveform and experimental parameters such as AC voltage and ion beam energy. This work discusses the experimental limitations of higher order stability zones in terms of operating and scan parameters. Lastly, this work also explored the ability to increase ion transmission in the digital quadrupole mass filter using only RF waveform duty cycle manipulation. This insight into the capacity and limitations of digitally operated quadrupole mass filters operating in higher order stability zones demonstrated in this work intends to add to the growing application and development of future of digitally operated quadrupole techniques.
Mill's Constant as an Information Singularity
Creators: name: 上田, 高之
Publisher: name: Zenodo
Year: 2025
Subjects: ミルズ定数
情報特異点
素数とブラックホール
数学哲学
不可見構造
量子論と認識論

description: This heuristic essay proposes a novel philosophical interpretation of Mill’s constant A as a mathematical black hole—an information singularity that emits prime numbers much like Hawking radiation.

By drawing parallels between prime prediction, black hole event horizons, and epistemic boundaries, this piece aims to redefine A as a structure visible only to a cosmic observer.

It questions the knowability of constants whose definition requires future data, and suggests a new angle: what if A is the observer’s shadow—always ahead, never within reach?
From Full Text Search to Semantic Web: The Infofox Project
Creators: name: Sigrist, Barbara
name: Schubert, Petra
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2003
Subjects: subject: Knowledge Management
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Infofox is a project launched by the Ecademy, the National Network of Excellence of the Swiss Universities of Applied Sciences for e-business and e-government. The paper discusses an envisioned improvement of the service level of the Ecademy Web site, an information portal which is set to integrate valuable information from the different member schools. The goal of the Infofox project is the development of an intelligent search engine. In order to fully exploit the potential of the information provided by the Ecademy members, the Infofox project team will need to implement aspects of a Semantic Web ? namely an ontology built upon a joint classification scheme and a set of inference rules. The RIP paper presents the basic concept and the results of the first phase of the project.
On the usage, privacy, and censorship of on-chain mixers
Creators: name: Wang, Zhipeng
Publisher: name: Imperial College London
Year: 2024

description: Permissionless blockchains offer pseudonymity rather than complete anonymity to their users. To enhance privacy for blockchain participants, on-chain mixers have been introduced. On-chain mixers enable users to deposit a fixed quantity of coins into a pool governed by smart contracts and subsequently withdraw those coins to a different address, thus breaking the linkability between users' addresses. In this thesis, we first examine the usage of existing on-chain mixers. We show the wide use of on-chain mixers by malicious actors seeking to launder money. Additionally, on-chain mixers have a privacy feature known as the anonymity set, allowing users to blend in with a set of k other users. Our empirical findings show that privacy-ignorant users fail to interact with mixers correctly, thus not contributing effectively to the anonymity set. Furthermore, we reveal that centralized regulators' sanctions have reduced the activities of on-chain mixers. We investigate the efficiency and potential security implications of censorship at various steps of a mixer-related transaction's lifecycle, including its generation, propagation, and validation. We indicate that fine-grained censorship could potentially lead to attacks. We also show that several blockchain application platforms' censorship is at the frontend level, and users can efficiently bypass the censorship using intermediary addresses. Lastly, we develop two approaches to achieve cost-effective and cost-fair on-chain mixers. The first one is the improved Merkle Pyramid Builder (iMPB) approach, in which we batch deposits to update the Merkle tree, and propose a mechanism to amortize deposit fees in the batch over time. Our evaluation results show that this approach can remarkably reduce up to 7× in the amortized deposit cost. Additionally, we show that combining the iMPB approach and off-chain verification can reduce the cost further. Our analysis shows that the improved mixers can guarantee the properties of correctness, privacy, availability, efficiency, and fairness.
Schlussbetrachtung Corporate Performance Management
Creators: name: Schubert, Petra
Publisher: name: Hanser
Year: 2004
Subjects: subject: Corporate Performance Management
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: ERP-Systeme bergen wertvolle Datenquellen für das strategische und operative Management, deren Erschliessung eine wesentliche Voraussetzung für das Corporate Performance Management ist.
Collaboration Platforms for Virtual Student Communities
Creators: name: Schubert, Petra
name: Koch, Michael
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2003
Subjects: subject: Personalisierung
subject: Virtual Communities
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: Since its inception, the Internet has served as a virtual meeting place for people sharing common interests. These electronically supported interest groups are nowadays called Virtual Communities. Networked computers are used to support direct communication and indirect information exchange, and to provide awareness and match-making services. The use of member profiles adds a new dimension to the support of the interaction between community members. Information about the members is needed to introduce the members to each other and to empower individualized services. The paper describes the research design of two empirical platform projects, one of them carried out in Germany, the other one in German-speaking Switzerland. Both projects are targeted at students and their respective needs for information, interaction and exchange.
Targeting Highly Structured RNA by Cooperative Action of siRNAs and Helper Antisense Oligomers in Living Cells
Creators: name: Dutkiewicz, Mariola
name: Ojdowska, Agata
name: Kuczynski, Jakub
name: Lindig, Vanessa
name: Zeichhardt, Heinz
name: Kurreck, Jens
name: Ciesiołka, Jerzy
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie

description: RNA target accessibility is one of the most important factors limiting the efficiency of RNA interference-mediated RNA degradation. However, targeting RNA viruses in their poorly accessible, highly structured regions can be advantageous because these regions are often conserved in sequence and thus less prone to viral escape. We developed an experimental strategy to attack highly structured RNA by means of pairs of specifically designed small interfering RNAs and helper antisense oligonucleotides using the 5’ untranslated region (5’UTR) of coxsackievirus B3 as a model target. In the first step, sites accessible to hybridization of complementary oligonucleotides were identified using two mapping methods with random libraries of short DNA oligomers. Subsequently, the accessibility of the mapped regions for hybridization of longer DNA 16-mers was confirmed by an RNase H assay. Using criteria for the design of efficient small interfering RNAs (siRNA) and a secondary structure model of the viral 5’UTR, several DNA 19-mers were designed against partly double-stranded RNA regions. Target sites for DNA 19-mers were located opposite the sites which had been confirmed as accessible for hybridization. Three pairs of DNA 19-mers and the helper 2’-O-methyl-16-mers were able to effectively induce RNase H cleavage in vitro. For cellular assays, the DNA 19-mers were replaced by siRNAs, and the corresponding three pairs of siRNA-helper oligomer tools were found to target 5’UTR efficiently in a reporter construct in HeLa cells. Addition of the helper oligomer improved silencing capacity of the respective siRNA. We assume that the described procedure will generally be useful for designing of nucleic acid-based tools to silence highly structured RNA targets.
User interface integration in corporate travel management: the case of the CWT Connect portal
Creators: name: Schubert, Petra
name: Voss, Andreas
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2004
Subjects: subject: Case Study
subject: Informatik
subject: 330 - Wirtschaft
subject: 005 - Computer Programmierung, Programme und Daten

description: This paper argues that technical integration is not the only reasonable choice in situations where access to data and functionality from different sources is critical. Rather, user interface integration, an approach in which integration takes place primarily in the mind of the user, can be a more favorable option. In this paper, CWT Connect, a travel management portal developed by Carlson Wagonlit Travel, is taken as a case of user interface integration. The paper starts with outlining frequent problems in integrating information systems and discusses how the portal metaphor is related to integration. The case of CWT Connect and its application at electrical engineering provider Cegelec is then depicted in detail.
Why do cavity nesters have a longer nestling period than open nesters? A comparative study of alternative hypotheses.
Creators: name: Tastayre, Corinne.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: Biology, Zoology.

description: To reduce predation on their progeny, passerines evolved two basic nesting patterns: (1) concealing nests or constructing them in inaccessible places, or (2) breeding inside cavities where offspring are relatively protected. These two nesting patterns seem to lead to different length of nesting cycle. Nice (1957) was the first to report that cavity-nesting species have a longer nestling period than open-nesting species. Why does such a difference in nestling period exist? The goals of my study were: (1) to verify the earlier observation that cavity nesters have a longer nestling period than open nesters; (2) to test the assumption that predation is more intense on nest contents of open nesters than cavity nesters, thereby presenting an important selective force favoring different lengths of the nestling periods of the two groups; and (3) to test two hypotheses on the occurrence of different length of nestling periods between the two groups of passerines. (Abstract shortened by UMI.)
Visual Processing in Body Dysmorphic Disorder: Investigating Eye Movements and Piloting a Novel Training Program
Creators: name: Beilharz, Francesca
Publisher: name: Swinburne
Year: 2024

description: Body dysmorphic disorder is a serious mental illness characterised by a preoccupation with perceived flaws in appearance. Current treatments do not target visual perception, which is a key feature of the disorder. Firstly, this research compared how people with body dysmorphic disorder and healthy controls view images using eye tracking. Secondly, the research evaluated a novel visual training program designed for body dysmorphic disorder. The program was considered feasible and acceptable, with potential for improving clinical outcomes. This research contributes to the understanding of body dysmorphic disorder, and how novel treatments may be used in conjunction with traditional psychotherapies.