cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ανάλυση ζήτησης εκμάθησης ξένων γλωσσών
Creators: name: Μαλλίρη, Βασιλική
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ξένες γλώσσες

description: Στο συνεχώς μεταβαλλόμενο οικονομικό και κοινωνικό περιβάλλον, όπου όλα τα κράτη μέλη της Ευρωπαϊκής Ένωσης είναι κομμάτι ενός πολυεθνικού δικτύου, η γνώση των ξένων γλωσσών είναι απολύτως απαραίτητη. Γι’ αυτό το λόγο η εκμάθηση δύο τουλάχιστον ξένων γλωσσών είναι υποχρεωτική στην Πρωτοβάθμια και Δευτεροβάθμια εκπαίδευση. Παρόλα αυτά, πολλές φορές η ανάγκη για ουσιαστική εκμάθηση και χρήση ξένων γλωσσών μετά την ολοκλήρωση της Δευτεροβάθμιας εκπαίδευσης καθίσταται απαραίτητη προτεραιότητα ή απλώς επιλογή. Στόχος της παρούσας εργασίας αποτελεί η εξέταση και η ανάλυση των κινήτρων των ενηλίκων αναφορικά με την επιλογή εκμάθησης ξένων γλωσσών, βάση των επαγγελματικών τους αναγκών και του επιπέδου των ξένων γλωσσών που γνωρίζουν ήδη. Σε αυτήν την εργασία, έγινε μία προσπάθεια διερεύνησης των προτιμήσεων & κινήτρων των ενηλίκων για επιλογή εκμάθησης ξένης γλώσσας, μέσω πρωτογενούς έρευνας συλλογής στοιχείων με τη μέθοδο ηλεκτρονικής συμπλήρωσης ερωτηματολόγιου. Η παρούσα αποτελείται από δύο βασικά τμήματα. Στο πρώτο τμήμα της εργασίας πραγματοποιήθηκε μια θεωρητική μελέτη της βιβλιογραφίας αναφορικά με την εκπαίδευση ξένων γλωσσών ενηλίκων, τη σημασία των ξένων γλωσσών και τα κίνητρα/προτιμήσεις ενηλίκων στην εκμάθησή τους. Στο δεύτερο τμήμα γίνεται ανάλυση του σκοπού της έρευνας που διεξήχθη, του ερωτηματολογίου και των αποτελεσμάτων της έρευνας βάση των απαντήσεων του δείγματος. Τέλος, παρουσιάζονται τα βασικά συμπεράσματα βάση της ανάλυσης των απαντήσεων που δόθηκαν και προτείνονται θέματα που χρήζουν περαιτέρω έρευνας.
EDS-MEMBED: Multi-sense embeddings based on enhanced distributional semantic structures via a graph walk over word senses
Creators: name: Ayetiran, Eniafe Festus
name: Sojka, Petr
name: Novotný, Vít
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: I.2.7
subject: 68T50

description: Several language applications often require word semantics as a core part of their processing pipeline, either as precise meaning inference or semantic similarity. Multi-sense embeddings (M-SE) can be exploited for this important requirement. M-SE seeks to represent each word by their distinct senses in order to resolve the conflation of meanings of words as used in different contexts. Previous works usually approach this task by training a model on a large corpus and often ignore the effect and usefulness of the semantic relations offered by lexical resources. However, even with large training data, coverage of all possible word senses is still an issue. In addition, a considerable percentage of contextual semantic knowledge are never learned because a huge amount of possible distributional semantic structures are never explored. In this paper, we leverage the rich semantic structures in WordNet using a graph-theoretic walk technique over word senses to enhance the quality of multi-sense embeddings. This algorithm composes enriched texts from the original texts. Furthermore, we derive new distributional semantic similarity measures for M-SE from prior ones. We adapt these measures to word sense disambiguation (WSD) aspect of our experiment. We report evaluation results on 11 benchmark datasets involving WSD and Word Similarity tasks and show that our method for enhancing distributional semantic structures improves embeddings quality on the baselines. Despite the small training data, it achieves state-of-the-art performance on some of the datasets.
New hints on nutrients dynamics and their impact on carbon sequestration in the Mediterranean Sea
Creators: name: Ibello, Valeria
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2009

description: In the World Ocean nitrogen and phosphorus cycles are deeply linked to the carbon cycle. As nitrate and phosphate play an important role in controlling biological production, the intensity of atmospheric carbon sequestration is strongly influenced by nutrient bioavailability. This thesis aims to contribute to the understanding of the ability of the Mediterranean Sea in absorbing C and N from the atmosphere.
The Mediterranean Sea presents several biogeochemical anomalies compared to the global ocean. The high nitrate/phosphate ratios in subsurface waters and the low 15N/14N ratios in particulate and dissolved nitrogen have suggested a significant occurrence of nitrogen fixation (N2 fixation) or an important impact of nitrogen atmospheric deposition.
This study presents, for the first time, a basin-wide overview of direct measurements of N2 fixation, with values in the North Atlantic for comparison. Very low N2 fixation rates (0.0520.031 nmols N l-1d-1) were observed in all sub-regions of the Mediterranean, in contrast to the higher values measured in the North Atlantic (0.3000.115 nmols N l-1d-1). Higher phosphorus (inorganic or organic) concentrations were not associated with higher N2 fixation rates.
An isotopic evaluation of the nitrogen sources based on isotopic signature of deep nitrate, N atmospheric deposition and Atlantic inflow nitrate, provides a rough estimate of the amount of N atmospheric deposition. The range varies between 22 and 60% of the total nitrate entering the Mediterranean Sea.
Large amount of N deposition from the atmosphere can explain both P-limitation and anomalous N/P ratio in deep layers. The external inputs of N, determining the excess of N in the marine system could ultimately fuel new production and enhance Mediterranean’s ability in carbon sequestration.
Oxygen-related traps in pentacene thin films: Energetic position and implications for transistor performance
Creators: name: Kalb, Wolfgang L.
name: Mattenberger, Kurt
name: Batlogg, Bertram
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We studied the influence of oxygen on the electronic trap states in a pentacene thin film. This was done by carrying out gated four-terminal measurements on thin-film transistors as a function of temperature and without ever exposing the samples to ambient air. Photooxidation of pentacene is shown to lead to a peak of trap states centered at 0.28 eV from the mobility edge, with trap densities of the order of 10(18) cm(-3). These trap states need to be occupied at first and cause a reduction in the number of free carriers, i.e. a consistent shift of the density of free holes as a function of gate voltage. Moreover, the exposure to oxygen reduces the mobility of the charge carriers above the mobility edge. We correlate the change of these transport parameters with the change of the essential device parameters, i.e. subthreshold performance and effective field-effect mobility. This study supports the assumption of a mobility edge for charge transport, and contributes to a detailed understanding of an important degradation mechanism of organic field-effect transistors. Deep traps in an organic field-effect transistor reduce the effective field-effect mobility by reducing the number of free carriers and their mobility above the mobility edge.
description: 13 pages, 14 figures, to be published in Phys. Rev. B
Statistics of Limit Root Bundles Relevant for Exact Matter Spectra of F-Theory MSSMs
Creators: name: Bies, Martin
name: Cvetič, Mirjam
name: Liu, Muyang
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Algebraic Geometry (math.AG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: In the largest, currently known, class of one Quadrillion globally consistent F-theory Standard Models with gauge coupling unification and no chiral exotics, the vector-like spectra are counted by cohomologies of root bundles. In this work, we apply a previously proposed method to identify toric base 3-folds, which are promising to establish F-theory Standard Models with exactly three quark-doublets and no vector-like exotics in this representation. The base spaces in question are obtained from triangulations of 708 polytopes. By studying root bundles on the quark doublet curve $C_{(\mathbf{3},\mathbf{2})_{1/6}}$ and employing well-known results about desingularizations of toric K3-surfaces, we derive a \emph{triangulation independent lower bound} $\check{N}_P^{(3)}$ for the number $N_P^{(3)}$ of root bundles on $C_{(\mathbf{3},\mathbf{2})_{1/6}}$ with exactly three sections. The ratio $\check{N}_P^{(3)} / N_P$, where $N_P$ is the total number of roots on $C_{(\mathbf{3},\mathbf{2})_{1/6}}$, is largest for base spaces associated with triangulations of the 8-th 3-dimensional polytope $Δ^\circ_8$ in the Kreuzer-Skarke list. For each of these $\mathcal{O}( 10^{15} )$ 3-folds, we expect that many root bundles on $C_{(\mathbf{3},\mathbf{2})_{1/6}}$ are induced from F-theory gauge potentials and that at least every 3000th root on $C_{(\mathbf{3},\mathbf{2})_{1/6}}$ has exactly three global sections and thus no exotic vector-like quark-doublet modes.
description: 6 pages, 5 figures and 2 tables
Model reference adaptive control of a manipulator in Cartesian coordinates
Creators: name: Voss, Henry Herbert
Publisher: name: University of British Columbia
Year: 2010

description: Robot performance is limited due to the form of the joint controllers. A model reference adaptive control scheme is proposed in which the reference model is in Cartesian coordinates. The form of the conventional joint controller is retained but the gains are adjusted to make the response similar to the reference model. By use of computer simulation the response of a manipulator to setpoint changes is examined for both the conventional and proposed control schemes. Improvements in path error for a straight line trajectory between starting and ending positions in world coordinates is observed with the new scheme compared with conventional control. The benefit is that fewer setpoints must be specified along a desired path to attain the desired path accuracy and, because of the form of the controller, servo errors will be higher leading to faster performance. Stability of the new scheme is examined by state space Floquet methods and a logical proof based on the adaption method used is given.
Isaac Hedges House, 61 North Main Street
Creators: name: East Hampton Star
Publisher: name: Unknown
Year: 0
Subjects: Photographs
Photos
Historic buildings
East Hampton
Structures
Dwellings
Main Street
Hedges Family

description: This image shows the Isaac Hedges House located at 61 North Main Street in East Hampton. This image was originally published by the East Hampton Star and this reproduction was collected sometime from 1970 to 1982 as part of the East Hampton’s Heritage Photo Collection.
description: Images within East Hampton Heritage Photo Collection seem to have been taken or collected in relation to the East Hampton Heritage project, but not all of them were included in the final publication. Several photographer are included in this collection.
Optical properties of nanostructured GaSb
Creators: name: Kildemo, M.
name: Nerbo, I. S.
name: Sondergard, E.
name: Holt, L.
name: Simonsen, I.
name: Stchakovsky, M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Optical measurements of nanostructured GaSb prepared by sputtering is presented. The optical response is studied by Mueller Matrix Ellipsometry (MME) in the visible range (430--850nm), and by spectroscopic ellipsometry in the range 0.6--6.5eV. The nano-structured surfaces reported in this work, consist of densely packed GaSb cones approximately 50nm high, on bulk GaSb. The nanostructured surfaces are here shown to considerably modify the optical response of the surface, hence giving a strong sensitivity to the far field spectroscopic (Mueller matrix) ellipsometric measurements. The off-specular scattering and the depolarization is found to be low. The anisotropic response is particularly emphasized by studying nano-structured GaSb cones approximately 45 degrees tilted with respect to the surface normal. In the latter case, one observes upon rotating the sample around the surface normal, that the Mueller matrix elements $m_{13}$ and $m_{14}$ oscillate as a function of the rotation angle. Finally, Mueller matrix techniques have been applied to the measured data, in order to analyze the acquired Mueller matrix in terms of physical realizability and noise.
description: Latex, 6 pages and 4 figures
Confirmation of xi^1 CMa's ultra-slow rotation: magnetic polarity reversal and a dramatic change in magnetospheric UV emission lines
Creators: name: Erba, C.
name: Shultz, M. E.
name: Petit, V.
name: Fullerton, A. W.
name: Henrichs, H. F.
name: Kochukhov, O.
name: Rivinius, T.
name: Wade, G. A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The magnetic beta Cep pulsator xi^1 CMa has the longest rotational period of any known magnetic B-type star. It is also the only magnetic B-type star with magnetospheric emission that is known to be modulated by both rotation and pulsation. We report here the first unambiguous detection of a negative longitudinal magnetic field in xi^1 CMa (=-87 +/- 2 G in 2019 and =-207 +/- 3 G in 2020), as well as the results of ongoing monitoring of the star's Halpha variability. We examine evidence for deviation from a purely dipolar topology. We also report a new HST UV spectrum of xi^1 CMa obtained near magnetic null that is consistent with an equatorial view of the magnetosphere, as evidenced by its similarity to the UV spectrum of beta Cep obtained near maximum emission. The new UV spectrum of xi^1 CMa provides additional evidence for the extremely long rotation period of this star via comparison to archival data.
description: 13 pages, Accepted 2021 May 14 to Monthly Notices of the Royal Astronomical Society 2021
Studio della formazione di uno spray di combustibile in camere di combustione a bassa pressione
Creators: name: Stolica, Riccardo
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2006

description: Il presente lavoro si pone come obiettivo principale quello di simulare numericamente il processo di atomizzazione primario e secondario in camere di combustione a bassa pressione  ed in modo particolare in tutte quelle applicazioni in cui vengono adoperati iniettori tipo "`pressure swirl"'
Per raggiungere questo scopo si è proceduto alla rivisitazione dei modelli di frantumazione del getto presenti nel simulatore fluidodinamico. E’ stato introdotto un modello che potesse simulare adeguatamente i fenomeni fisici legati alla frantumazione della lamina fluida uscente dall’ugello. Date le basse pressioni dell'ambiente in cui si inietta, inoltre, i numeri di Weber che si raggiungono sono dell'ordine delle decine, questo significa che il fenomeno del break-up si presenta abbastanza vario da non poter essere simulato con un unico modello matematico (TAB o WAVE). Questo a condotto allo sviluppo di un modello ibrido che è in grado di operare una scelta sul modello da adoperare in funzione del regime di atomizzazione in cui si trova la goccia.
Per validare i modelli adoperati vengono proposti quattro casi di studio su combustori di nuova generazione.
Transparently Reported Research: An analysis of Wellcome-funding publications in 2016 and 2019
Creators: name: Borrelli, Leslie McIntosh
name: Sumner, Josh
name: Vitale, Cynthia
Publisher: name: Wellcome Trust
Year: 2021
Subjects: subject: 160511 Research, Science and Technology Policy
subject: FOS: Political science
subject: Science Policy

description: This report from Ripeta summarises the transparency reporting practices of Wellcome Trust-funded research during the years of 2016 and 2019. Ripeta analysed 3100 Wellcome-funded research articles from each year, assessing key criteria important to transparently reported research – including presence of a data availability statement, location of available data, and reporting of analysis software and code. For more information about Ripeta, see https://www.ripeta.com/
Non-localities in nucleon-nucleus potentials
Creators: name: Fraser, P.
name: Amos, K.
name: Karataglidis, S.
name: Canton, L.
name: Pisent, G.
name: Svenne, J. P.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Two causes of non-locality inherent in nucleon-nucleus scattering are considered. They are the results of two-nucleon antisymmetry of the projectile with each nucleon in the nucleus and the dynamic polarization potential representation of channel coupling. For energies $\sim 40 - 300$ MeV, a g-folding model of the optical potential is used to show the influence of the knock-out process that is a result of the two-nucleon antisymmetry. To explore the dynamic polarization potential caused by channel coupling, a multichannel algebraic scattering model has been used for low-energy scattering.
description: 12 pages, 11 figures, submitted to EPJA
Russian poetic translation on the pages of «Russkoe Slovo»: Bibliography
Creators: name: Zhatkin, Dmitry
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 470507
subject: Comparative and transnational literature
classificationCode: 470514
subject: Literary theory
classificationCode: 470599
subject: Literary studies not elsewhere classified

description: The article is devoted to the consideration of the specifics of poetic translations published in the magazine «Russkoe Slovo» (1859-1866), understanding the circle of translated authors and their works, the evolution of poetic translation taking into account the change in the ideological concept of the publication. The appendix to the article provides a complete bibliography of Russian translations, as well as poems «on the motif» of works of Western European literature, published on the pages of «Russkoe Slovo».
Preliminary Multimodal Deep Learning Investigation of Tumor Immune Microenvironment Cell-Type Deconvolution for Colorectal Cancer Prognostication
Creators: name: Azher, Zarif
name: Nithilaselvan, Salban
name: DeVictor, Tristan
name: Zhang, Eric
name: Panja, Tanay
name: Prabu, Rishabh
name: Chen, Ji-Qing
name: Christensen, Brock
name: Salas, Lucas
name: Vaickus, Louis
name: Levy, Joshua
Publisher: name: Zenodo
Year: 2023

description: Abstract

 

Background: Deep learning technologies can learn complex patterns from input patient data (ex; histopathology, DNA methylation) to predict clinically useful cancer-related endpoints (ex; survival). Multimodal methods fuse together information from heterogeneous modalities, to make more informed predictions. The tumor microenvironment (TME) is characterized by a mosaic of immune cell types whose composition – which can be deconvolved from “omics” data – may hold clues regarding a patient’s unique disease profile and progression. Existing deep learning-driven multimodal methods do not incorporate this important data type into machine learning prognostication models. Methods: Here, we develop a multimodal deep learning model which integrates patient histopathological imaging, bulk DNA methylation profiling, and deconvolved cellular proportions from 17 lineages using HiTIMED, to predict colorectal cancer patient prognosis (ie: instantaneous risk of death). Data was collected and preprocessed from 414 patients from The Cancer Genome Atlas (TCGA). Unimodal prognostication models were trained to derive numerical representations from each modality. The final multimodal model fused together these representations to learn a joint information space and subsequently predict patient prognosis. Models were assessed using concordance index (c-index) measured on a heldout testing dataset partition.Results and Conclusions: Unimodal models using histopathology (0.593 ± 0.003), DNA methylation (0.615 ± 0.001), and immune cell proportions (0.623 ± 0.003) were similarly powerful independent predictors of prognosis measured via C-Index. The multimodal model (0.672 ± 0.002) brought an average performance increase of 4.4%. This performance was comparable and potentially superior versus other reported multimodal colorectal cancer prognostication methods (0.640 ± 0.007, 0.650 ± 0.005). Our results demonstrate that TME-related cell profiles should be considered a capable modality for independent and joint investigation of actionable cancer outcome prediction. Future works will apply this modality to additional predictive tasks, and conduct ablation studies to understand how TME data can uncover novel biological insights.

 

Note: Updated from https://f1000research.com/posters/12-1559.
Topological deformation of isolated horizons
Creators: name: Liko, Tomas
Publisher: name: arXiv
Year: 2007
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show that the Gauss-Bonnet term can have physical effects in four dimensions. Specifically, the entropy of a black hole acquires a correction that is proportional to the Euler characteristic of the cross sections of the horizon. While this term is constant for a single black hole, it will be a non-trivial function for a system with dynamical topologies such as black-hole mergers: it is shown that for certain values of the GB parameter, the second law of black-hole mechanics can be violated.
description: 8 pages; 1 figure; v2: 9 pages; some comments added at the end; 3 references added; v3: minor corrections; v4: some corrections; discussion added on black-hole mergers and violations of the second law; 2 references added; v5: minor corrections; v6: final corrections to match PRD version
Measurement of the Angular Distribution of Wavelength-Shifted Light Emitted by TPB
Creators: name: Schrott, Jackson
name: Sakai, Michinari
name: Naugle, Samuel
name: Gann, Gabriel Orebi
name: Kravitz, Scott
name: McKinsey, Daniel
name: Smith, Ryan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We present measurements of the angular distribution of re-emitted light from tetraphenyl butadiene thin films when exposed to \SI{128}{nm} light in vacuum. Films ranging from \SI{250}{nm} to \SI{5.5}{\micron} in thickness are measured. All films were fabricated by evaporation deposition on ultraviolet transmitting (UVT) acrylic substrates. Preliminary comparisons of the angular distribution to that produced by a detailed Monte Carlo model are also presented. The current shortcomings of the model are discussed and future plans briefly outlined.
Novel therapeutic approaches with small activating RNA
Creators: name: Andrikakou, Pinelopi
Publisher: name: Imperial College London
Year: 2020

description: Oligonucleotide therapeutics is a major platform for drug discovery with great potential for diseases where endogenous gene expression is downregulated. In 2016, MTL-CEBPA was the first RNA activating oligonucleotide drug targeting CEBPA to enter clinical development for patients with advanced hepatocellular carcinoma (HCC). The aim of this PhD project is to develop new therapeutic small activating RNAs (saRNAs) for genes which are suppressed in the pathology of inflammation, Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steato-Hepatitis (NASH). saRNAs for three different targets namely Sirtuin 1 (SIRT1), Hepatocyte Nuclear Factor 1-Alpha (HNF1A) and Fibroblast Growth Factor 21 (FGF21) are investigated. SIRT1 is a protein with anti-apoptotic, anti-ageing and anti-inflammatory properties. SIRT1-PR57 saRNA is identified as the most promising candidate to upregulate SIRT1 mRNA and protein levels. The therapeutic potential of SIRT1-PR57 saRNA is experimentally explored in cell models of lipid metabolic disorders as well as inflammatory diseases and is the central theme of this thesis. Other targets touched upon but not fully explored include HNF1A and FGF21. HNF1A is a liver enriched transcription factor involved in Maturity Onset Diabetes of the Young (MODY), pancreatic ductal adenocarcinoma (PDAC) and HCC. HNF1A-PR1 saRNA is shown to successfully upregulate the mRNA levels of the HNF1A(A) isoform, while protein levels still require further validation. Investigation in relation to FGF21, a metabolic hormone regulating lipid metabolism, demonstrated that the FGF21 transcript is not present in hepatocytes. FGF21 saRNA candidates might yield more promising results in other liver cell lines with the potential to reverse the pathology of NAFLD and NASH. Finally, SIRT1 saRNA could have therapeutic effect as an anti-inflammatory regulatory component within macrophages.
La Rochefoucauld : héroisme et idéologie noble
Creators: name: Combet, Denis P.
Publisher: name: University of British Columbia
Year: 2010

description: The influence of Saint-August in on the moral literature of the seventeenth-century cannot be overlooked. The thinking of Port-Royal and the Jansenists influenced the works of Pascal and La Rochefoucauld. In the writings of La Rochefoucauld which will be considered in this study, the theme of self-love in the Maximes tends to confirm the important role of Augustinian philosophy. However, the Maximes and Reflexions Diverses brought to light other currents of thought Less known texts such as l'Apologie du Prince de Marcillac and the Memoires strongly represent the heroic mind based on the chivalry. This study will show the importance of aristocratic ideology, heroism, and social prejudice on the moral thinking of La Rochefoucauld. First, the different cultures will be defined by using examples from the Maximes. In Augustinism, "wordly" culture appears as a mixture of the religious of the secular cultures. Hence, obvious humour appears in the Maximes. Moreover, a criticism of the monarchy under Louis XIV appears in some maxims. Even the political involvement of the author finds its way into the genre of the maxim itself. The second chapter will examine the links between the aristocratic ideology and Augustinism philosophy. The heroic tone found in some maxims and the author's Memoires is closely related to that of Corneille. Indeed, some maxims concerning self-interest, the passions, nature, moral superiority and courage retain stoic overtones. Thus the concept of Cornelian heroism as formulated in the XIVth century and in the first half of the XVIIth by Du Vair, Montaigne, Charron, and Juste Lipse is still very much alive in the works of La Rochefoucauld.
Constraining the Overcontact Phase in Massive Binary Evolution I. Mixing in V382 Cyg, VFTS 352, and OGLE SMC-SC10 108086
Creators: name: Abdul-Masih, Michael
name: Sana, Hugues
name: Hawcroft, Calum
name: Almeida, Leonardo A.
name: Brands, Sarah A.
name: de Mink, Selma E.
name: Justham, Stephen
name: Langer, Norbert
name: Mahy, Laurent
name: Marchant, Pablo
name: Menon, Athira
name: Puls, Joachim
name: Sundqvist, Jon
Publisher: name: arXiv
Year: 2021
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: As potential progenitors of several exotic phenomena including gravitational wave sources, magnetic stars, and Be stars, close massive binary systems probe a crucial area of the parameter space in massive star evolution. Despite the importance of these systems, large uncertainties regarding the nature and efficiency of the internal mixing mechanisms still exist. In this work, we aim to provide robust observational constraints on the internal mixing processes by spectroscopically analyzing a sample of three massive overcontact binaries at different metallicities. Using optical phase-resolved spectroscopic data, we perform an atmosphere analysis using more traditional 1D techniques and using state-of-the-art 3D techniques. We compare and contrast the assumptions and results of each technique and investigate how the assumptions affect the final derived atmospheric parameters. We find that in all three cases, both components of system are highly overluminous indicating either efficient internal mixing of helium or previous non-conservative mass transfer. However, we do not find strong evidence of helium or CNO surface abundance changes usually associated with mixing. Additionally, we find that in unequal mass systems, the measured effective temperature and luminosity of the less massive component places it very close to the more massive component on the Hertzsprung-Russell diagram. These results were obtained independently using both of the techniques mentioned above, which suggests that these measurements are robust. The observed discrepancies between the temperature and the surface abundance measurements when compared to theoretical expectations indicate that unaccounted for additional physical mechanisms may be at play.
description: Accepted for publication in A&A; 28 pages, 20 figures
Nonergodic dynamics of the one-dimensional Bose-Hubbard model with a trapping potential
Creators: name: Kunimi, Masaya
name: Danshita, Ippei
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate nonergodic behavior of the one-dimensional Bose-Hubbard model, which emerges in the unitary quantum dynamics starting with initial-state $|ψ(0)\rangle=|\cdots 2020\cdots \rangle$ in the presence of a trapping potential. We compute the level spacing statistic, the time evolution of the number imbalance between the odd and the even sites, and the entanglement entropy in order to show that the system exhibits nonergodicity in a strongly interacting regime. The trapping potential enhances nonergodicity even when the trapping potential is weak compared to the the hopping energy. We derive the effective spin-1/2 {\it XXZ} Hamiltonian for the strongly interacting regimes by using a perturbation method. On the basis of the effective Hamiltonian, we show that the trapping potential is effectively strengthened by the on-site interaction, leading to the enhancement of the nonergodic behavior. We also calculate the real-time dynamics under the effective Hamiltonian and find that the entanglement entropy grows logarithmically in time.
description: 10 pages, 10 figures
Exploring the effect of sex on an empirical fitness landscape
Creators: name: de Visser, J. Arjan G. M.
name: Park, Su-Chan
name: Krug, Joachim
Publisher: name: arXiv
Year: 2008
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: The nature of epistasis has important consequences for the evolutionary significance of sex and recombination. Recent efforts to find negative epistasis as source of negative linkage disequilibrium and associated long-term sex advantage have yielded little support. Sign epistasis, where the sign of the fitness effects of alleles varies across genetic backgrounds, is responsible for ruggedness of the fitness landscape with implications for the evolution of sex that have been largely unexplored. Here, we describe fitness landscapes for two sets of strains of the asexual fungus \emph{Aspergillus niger} involving all combinations of five mutations. We find that $\sim 30$% of the single-mutation fitness effects are positive despite their negative effect in the wild-type strain, and that several local fitness maxima and minima are present. We then compare adaptation of sexual and asexual populations on these empirical fitness landscapes using simulations. The results show a general disadvantage of sex on these rugged landscapes, caused by the break down by recombination of genotypes escaping from local peaks. Sex facilitates escape from a local peak only for some parameter values on one landscape, indicating its dependence on the landscape's topography. We discuss possible reasons for the discrepancy between our results and the reports of faster adaptation of sexual populations.
Use of Dried Distiller Grain Solubles as A Feed Ingredient in The Diets of Livestock
Creators: name: Ankur Mishra1, Akash wadal1, D. Tewari2, V.K Singh3, Nidhi Verma4, Sonu Jaiswal5
Publisher: name: The Science world a Monthly e magazine
Year: 2023

description: Identifying alternative fuels produced from plant biomass is essential due to the potential depletion of non-renewable energy sources plus the negative impact that burning them causes to the environment. Distillers' dried grain with soluble (DDGS) is a residual product obtained from the process of bioethanol fermentation. This process involves the use of dry milling technology on grains that are high in starch, such as corn, wheat, and barley. The present surge in bioethanol is driven by the demand for sustainable liquid fuels, particularly in the transportation industry. Due to its high content of crude protein, fat, fiber, vitamins, and minerals, DDGS is presently employed as feed for aquaculture, livestock, and poultry. DDGS has been utilized as a feedstock in the manufacturing of value-added goods through microbial fermentation in recent years. Several investigations have documented the generation of organic acids, methane, biohydrogen, and hydrolytic enzymes by the utilization of DDGS. Pretreatment of DDGS is necessary to extract the fermentable sugars, despite the significant presence of macronutrients in DDGS. The pre-treatment procedures, which might be of chemical, physical, or biological origin, are employed either individually or in combination to achieve optimal yields for various applications.
Detecting dark matter subhalos with the Nancy Grace Roman Space Telescope
Creators: name: Pardo, Kris
name: Doré, Olivier
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The dark matter subhalo mass function is a promising way of distinguishing between dark matter models. While cold dark matter predicts halos down to Earth-sized masses, other dark matter models typically predict a cut-off in the subhalo mass function. Thus a definitive detection or limits on the existence of subhalos at small masses can give us insight into the nature of dark matter. If these subhalos exist in the Milky Way, they would produce weak lensing signatures, such as modified apparent positions, on background stars. These signatures would generate correlations in the apparent velocities and accelerations of these stars, which could be observable given sufficient astrometric resolution and cadence. The Nancy Grace Roman Space Telescope's Exoplanet Microlensing Survey will be perfectly suited to measuring the acceleration signatures of these halos. Here we forward model these acceleration signatures and explore the Roman Space Telescope's future constraints on lens profiles and populations. We find that the Roman Space Telescope could place competitive bounds on point source, Gaussian, and Navarro-Frenk-White (NFW) profile lenses that are complementary to other proposed methods. In particular, it could place 95% upper limits on the NFW concentration, $c_{200} < 10^{2.5}$. We discuss possible systematic effects that could hinder these efforts, but argue they should not prevent the Roman Space Telescope from placing strong limits. We also discuss further analysis methods for improving these constraints.
description: 11 pages, 6 figures. v2: small text changes. accepted for publication in PRD
What is the Research Data Alliance and what will it do for you?
Creators: name: Vasiljevic, Nikola
Publisher: name: Zenodo
Year: 2019
Subjects: Research Data Alliance
Data
Wind energy
Open data

description: The Research Data Alliance (RDA) was launched as a community-driven initiative in 2013 by the European Commission, the United States Government's National Science Foundation and National Institute of Standards and Technology, and the Australian Government’s Department of Innovation with the goal of building the social and technical infrastructure to enable open sharing and re-use of data. The RDA vision is to help researchers and innovator to openly share data across technologies, disciplines and countries to address the grand challenges of society. It has a mission to build the social and technical bridges to enable open sharing of data. The RDA has over 8400 members associated with 100 dedicated groups who are working on global interoperability challenges outputting data related best practices, guidelines and recommendations. In 2019, the wind energy (WE) domain got under the RDA umbrella through an ambassador call that should assure a bridge between WE domain and RDA communities. Currently, we are working on a survey, identification and selection of RDA outputs, working groups and interest groups which are of interest for the WE domain. This preliminary step will represent a cornerstone for the development of the RDA WE interest group which should assure synchronization of the data related activities across the wind energy domain. In our talk, we intend to present results of this work, followed with an outline of the WE Interest Group development plan and make an open call for everyone who would like to take an active part in the group growth.
The spectrum of scalar-meson nonets in the Resonance-Spectrum Expansion
Creators: name: van Beveren, Eef
name: Rupp, George
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We argue that the low-lying scalar-meson nonet makes part of a subset of a family of infinitely many scalar-meson nonets, which in turn makes part of a family of infinitely many quark-antiquark bound states and resonances. We outline the properties of this subset.
description: Talk presented at the workshop on "Scalar Mesons and Related Topics" honoring the 70th birthday of Michael Scadron, 11 pages, 7 figures
RADICALZ Public Summary of Deliverable D2.3
Creators: name: Hidalgo, Aurelio
Publisher: name: Zenodo
Year: 2024

description: D2.3: Microfluidic assay for detection of glycopolymer synthesizing enzymes

Within RADICALZ, partner INSAT plays a central role by bringing its expertise on polymers and enzymes that allow their tailored production from sugars. These polymers, called polysaccharides or glycopolymers, are a key element of the current and future bioeconomy because they are derived from renewable ressources contrarily to petroleum-based polymers that are are damaging the environment and are made up from non-renewable ressources. However, in order to get these new bio-based polymers fullfil the same roles as the old ones – and there are many – they have to be tailored to fit for each application: for instance, food-based polymers are not the same as those found in laundry products or cosmetics. The next step is to find the appropriate enzymes that will generate each of these tailorized polymers. INSAT has built decades of renowned expertise to find or to engineer enzymes with a focus on those active on sugars, the carbohydrate active enzymes.

Although very efficient, the current methods used for enzyme discovery and engineering are not fast enough to bring the adequate enzymes to industry in a timely manner and therefore at a competitive cost. This is where microfluidics comes into play. This new technology is a game changer for what we are doing at INSAT. A few numbers: One single robust and efficient enzyme is typically found in Nature or through an enzyme engineering strategy for every 100,000 candidates tested. Conventionally, each of these candidates has to be tested individually using robotics and automated methods in which each candidate is assayed in a 100-microlitre mini test tube. Microfluidics on the contrary relies on the miniaturization of the classical test tube to picolitre dimensions (0.000001 microlitre) by means of water-in-oil droplets that are generated in microfluidic devices. In this format, a million candidates can be tested within a single day while it would take few months to perform the same using robots. The price of such a campaign is thus dramatically reduced: machinery and operating costs are typically 100- 1000 times cheaper and the carbon footprint (plasticware, chemicals) is decreased by 99%.

Efforts in RADICALZ (partner INSAT) have focused on the development of new microfluidics tools to screen for glycopolymer-forming enzymes. As an example (figure), it is shown that using an enzyme known for polymer synthesis, it is isolated within a droplet and easily distinguished from other candidates that cannot perform the reaction.
Caratterizzazione di geni che influenzano la prolificità nelle razze ovine autoctone Bagnolese e Laticauda allevate
in regione Campania
Creators: name: Solimene, Roberta
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2013

description: Le razze autoctone rappresentano una risorsa importante per le regioni di origine, tuttavia per effetto del fenomeno di globalizzazione, che ha coinvolto anche la zootecnia, il loro allevamento è andato quasi scomparendo nel corso degli ultimi decenni. Attualmente si stanno rivalutando i vantaggi che l’allevamento di queste razze può presentare. Nell’ambito di un progetto di rivalutazione delle razze autoctone della regione Campania denominato RARECA (PSR Campania 2007-2013 Misura 214) è stato condotto uno studio su due razze ovine allevate in regione Campania: la Bagnolese e la Laticauda. Tali razze sono particolarmente apprezzate dagli allevatori, oltre che per la notevole rusticità, per l’elevato numero di parti plurimi e gli alti tassi di prolificità (180% Laticauda; 170% Bagnolese). Numerosi studi hanno evidenziato che l’elevata prolificità di alcune razze ovine è associata alla presenza di particolari varianti alleliche dei geni BMPR1B (FecB), BMP15 (FecX) e GDF9 (FecG), si è voluto pertanto verificare se tali varianti alleliche fossero presenti anche negli ovini Bagnolese e Laticauda. Attraverso l’utilizzo della PCR, PCR-RFLP e l’analisi di sequenza, è stato possibile verificare che le due razze studiate non presentano l’allele FecB del gene BMPR1B e non presentano particolari polimorfismi del gene BMP15 mentre presentano vari polimorfismi nell’esone 2 del gene GDF9, alcuni dei quali non ancora evidenziati in altre razze ovine. Per comprendere pienamente l’origine ed il significato di tali polimorfismi sono necessari ulteriori studi che dovranno coinvolgere un numero maggiore di soggetti e di allevamenti.
A survey of heavy-heavy hadronic molecules
Creators: name: Dong, Xiang-Kun
name: Guo, Feng-Kun
name: Zou, Bing-Song
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The spectrum of hadronic molecules composed of heavy-antiheavy charmed hadrons has been obtained in our previous work. The potentials are constants at the leading order, which are estimated from resonance saturation. The experimental candidates of hadronic molecules, say $X(3872)$, $Y(4260)$, three $P_c$ states and $P_{cs}(4459)$, fit the spectrum well. The success in describing the pattern of heavy-antiheavy hadronic molecules stimulates us to give more predictions for the heavy-heavy cases, which are less discussed in literature than the heavy-antiheavy ones. Given that the heavy-antiheavy hadronic molecules, several of which have strong experimental evidence, emerge from the dominant constant interaction from resonance saturation, we find that the existence of many heavy-heavy hadronic molecules is natural. Among these predicted heavy-heavy states we highlight the $DD^*$ molecule and the $D^{(*)}Σ_c^{(*)}$ molecules, which are the partners of the famous $X(3872)$ and $P_c$ states. Quite recently, LHCb collaboration reported a doubly charmed tetraquark state, $T_{cc}$, which is in line with our results for the $DD^*$ molecule. With the first experimental signal of this new kind of exotic states, the upcoming 3pdate of the LHCb experiment as well as other experiments will provide more chances of observing the heavy-heavy hadronic molecules.
description: v3: the published version, mistakes about the quantum numbers of identical di-baryon system corrected and 122 double-charm hadronic molecules; v2: more discussion added and references updated; v1: 20 pages, 6 figures and 124 double-charm hadronic molecules including the recently discovered T_{cc} in LHCb measurement
On the notion of gauge symmetries of generic Lagrangian field theory
Creators: name: Giachetta, G.
name: Mangiarotti, L.
name: Sardanashvily, G.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: General Lagrangian theory of even and odd fields on an arbitrary smooth manifold is considered. Its non-trivial reducible gauge symmetries and their algebra are defined in this very general setting by means of the inverse second Noether theorem. In contrast with gauge symmetries, non-trivial Noether and higher-stage Noether identities of Lagrangian theory can be intrinsically defined by constructing the exact Koszul-Tate complex. The inverse second Noether theorem that we prove associates to this complex the cochain sequence with the ascent operator whose components define non-trivial gauge and higher-stage gauge symmetries. These gauge symmetries are said to be algebraically closed if the ascent operator can be extended to a nilpotent operator. The necessary conditions for this extension are stated. The characteristic examples of Yang-Mills supergauge theory, topological Chern-Simons theory, gauge gravitation theory and topological BF theory are presented.
description: 27 pages, accepted for publication in J. Math. Phys
An attempt to define the therapeutic use of Dipyridamole in triple-negative breast-cancer patients-a proof of concept in animal model-
Creators: name: De Martino, Daniela
Publisher: name: Università degli Studi di Napoli Federico II
Year: 2013

description: Dipyridamole belongs to the category of antiplatelet drugs commonly used in cardiovascular disease, here we want test its effectiveness in the treatment of triple-negative breast-cancer. In-vitro assays were used to analyze the perturbations induced by dipyridamole on the cell cycle, on cell growth and motility. We also want to assess the dipyridamole action on Wnt, NF-kB and ERK1/2-MAPK signaling pathways that are overactive in such tumors. Here we provide the evidence that dipyridamole is able to perturb also in vivo the activation of these important pathways and inhibit the infiltration of immune cells within the tumor mass that may control the tumor growth and propagation of metastasis. Xenograft mice bearing triple-negative breast-cancer 4T1-Luc cells were generated to investigate the primary tumor growth, metastasis formation and serum inflammatory cytokines levels. In vivo, dipyridamole significantly reduced primary tumor growth and metastasis formation, indeed treatment with 60 mg/kg/day dipyridamole reduced mean primary tumor size by 76.7% (p = 0.0429), while treatment with 30 mg/kg/day dipyridamole resulted in an almost a total reduction in metastasis formation (p = 0.0292). Immunohistochemical analyses reveal significant effects of dipyridamole on the Wnt, ERK1/2-MAPK and NF-kB pathways in primary tumor animal models. In vivo dipyridamole decreased activated β-catenin by 38.64 % (p <0.0001), phospho-ERK1/2 by 25.05 % (p =0.0129), phospho-p65 by 67.82 % (p <0.0001) and doubled the expression of IkBa (p = 0.0019), thus revealing significant effects on Wnt, ERK1/2-MAPK and NF-kB pathways in 4T1-Luc xenograft animal model. Moreover dipyridamole significantly decreased the infiltration of tumor-associated macrophages and myeloid-derived suppressor cells in primary tumors (p <0.005), and the inflammatory cytokines levels in the sera of the treated mice. We suggest that when used at appropriate doses and with the correct mode of administration, dipyridamole is a promising agent for breast-cancer treatment, thus also implying its potential use in other cancers that show highly activated Wnt, ERK1/2-MAPK and NF-kB pathways.