cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Utility of Extrapyramidal Signs and Psychosis as Predictors of Cognitive and Functional Decline, Nursing Home Admission, and Death in Alzheimer's Disease: Prospective Analyses from the Predictors Study
Creators: name: Stern, Yaakov
name: Albert, Marilyn
name: Brandt, Jason
name: Jacobs, Diane
name: Tang, Mingxin
name: Marder, Karen
name: Bell, Karen L.
name: Sano, Mary
name: Devanand, Devangere P.
name: Bylsma, Fred
name: Lafleche, Ginette
Publisher: name: Columbia University
Year: 1994
Subjects: Neurology
Psychosis
Cognition
Alzheimer's disease--Forecasting

description: Objective: To examine whether either extrapyramidal signs or psychotic features are associated with more rapid progression of Alzheimer's disease. Background: It has been unclear whether extrapyramidal signs and psychosis are predictors of faster course or are simply late signs. Methods: Two hundred thirty-six patients with mild Alzheimer's disease were recruited in three cities and followed semiannually. Results: Using Cox proportional hazards models that adjusted for age, sex, disease severity, and estimated duration of illness at study entry, the presence of extrapyramidal signs at entry was associated with higher relative risk (RR) of reaching moderate cognitive (RR = 2.35, 95% CI = 1.12 to 4.92) or functional (RR = 2.31, 95% CI = 1.37 to 3.90) severity, nursing home entry (RR = 2.51, 95% CI = 1.32 to 4.76), or death (RR = 3.04, 95% CI = 1.31 to 7.05). Psychosis predicted only the functional end point (RR = 1.85, 95% CI = 1.18 to 2.90). Using regression models, modified Mini-Mental State scores declined 1.30 points (95% CI = 0.16 to 2.44) per 6-month interval, more among patients with than those without extrapyramidal signs; patients with psychosis declined 1.15 (95% CI = 0.52 to 1.77) more mMMS points per interval. Conclusions: This study confirms extrapyramidal signs and psychosis as robust predictors of disease end points and rapid progression in Alzheimer's disease.
Non-modal disturbances growth in a viscous mixing layer flow
Creators: name: Gelfgat, Helena Vitoshkin Alexander
Publisher: name: arXiv
Year: 2012
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Non-modal transient growth of disturbances in a viscous mixing layer flow is studied for the Reynolds numbers varying from 100 up to 5000 at different streamwise and spanwise wavenumbers. By comparing results of several mathematical approaches, it is concluded that the non-modal optimal disturbances growth results from the discrete part of the spectrum only. It is found that in the linearly unstable configurations the non-modal growth cannot be larger than the exponential one. At the same time, the largest non-modal growth takes place at the wavenumbers for which the mixing layer flow is stable. The most profound growth is attained by oblique three-dimensional waves that propagate at the angle close to 45o with respect to the base flow. Results of the non-modal analysis are followed by the fully non-linear three-dimensional time-dependent solutions, initial conditions for which are taken as the calculated optimal vectors. The fully 3D non-linear calculations exhibit growth and decay of flow structures that sometimes become similar to those observed at late stages of time evolution of the Kelvin-Helmholtz billows. It is shown that non-modal optimal disturbances yield a strong mixing without a transition to turbulence.
description: 30 pages, 15 figures, 5 tables
Tritiated Imipramine Binding: A Peripheral Marker for Serotonin in Parkinson's Disease
Creators: name: Sano, Mary
name: Stanley, Michael
name: Lawton, Arlene
name: Cote, Lucien J.
name: Williams, Janet B. W.
name: Stern, Yaakov
name: Marder, Karen
name: Mayeux, Richard Paul
Publisher: name: Columbia University
Year: 1991
Subjects: Neurology
Parkinson's disease
Serotonin
Imipramine

description: Tritiated imipramine binding in platelets has been used to evaluate serotonin activity in depression in previous studies. This article examined this marker as a possible measure of central nervous system serotonergic activity for depression in patients with Parkinson's disease (PD). The number of binding sites was significantly lower in depressed patients with PD than in a healthy control group. Patients with PD who were not depressed had lower values than the comparison group, but this difference was not significant. We also found a significant correlation between the receptor site values in platelets and cerebrospinal fluid levels of the serotonin metabolite, 5-hydroxyindoleacetic acid (r =.59), but this was independent of a diagnosis of depression. Receptor site values were examined to identify appropriate cutoff scores to predict depression in the group of patients with PD. A maximum sensitivity of 50% was achieved with a specificity of 64%. Our results strongly support a generalized alteration in serotonin metabolism in depressed patients with PD, but tritiated imipramine binding in platelets is not a useful diagnostic tool for depression.
Utilization of Antihypertensives, Antidepressants, Antipsychotics, and Hormones in Alzheimer Disease
Creators: name: Zhu, Carolyn W.
name: Livote, Elayne E.
name: Kahle-Wrobleski, Kristin
name: Scarmeas, Nikolaos
name: Albert, Marilyn
name: Brandt, Jason
name: Blacker, Deborah
name: Sano, Mary
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 2011
Subjects: Alzheimer's disease--Treatment
Hypotensive agents
Antidepressants
Antipsychotic drugs
Hormone therapy

description: This study explores the longitudinal relationship between patient characteristics and use of 4 drug classes (antihypertensives, antidepressants, antipsychotics, and hormones) that showed significant changes in use rates over time in patients with Alzheimer disease. Patient/caregiver-reported prescription medication usage was categorized by drug class for 201 patients from the Predictors Study. Patient characteristics included use of cholinesterase inhibitors and/or memantine, function, cognition, living situation, baseline age, and sex. Assessment interval, year of study entry, and site were controlled for. Before adjusting for covariates, useage increased for antihypertensives (47.8% to 62.2%), antipsychotics (3.5% to 27.0%), and antidepressants (32.3% to 40.5%); use of hormones decreased (19.4% to 5.4%). After controlling for patient characteristics, effects of time on the use of antidepressants were no longer significant. Antihypertensive use was associated with poorer functioning, concurrent use of memantine, and older age. Antipsychotic use was associated with poorer functioning and poorer cognition. Antidepressant use was associated with younger age, poorer functioning, and concurrent use of cholinesterase inhibitors and memantine. Hormone use was associated with being female and younger age. Findings suggest accurate modeling of the Alzheimer disease treatment paradigm for certain subgroups of patients should include antihypertensives and antipsychotics in addition to cholinesterase inhibitors and memantine.
Voltage-gated potassium ion channels : evolution, functional variation and human disease
Creators: name: Jackson, Heather Ann
Publisher: name: University of British Columbia
Year: 2012

description: Hyperpolarization-activated cyclic nucleotide gated (HCN) channels are structurally similar to voltage gated potassium channels and play pivotal roles in cellular pacemaking. Their physiological relevance is illustrated by the fact that genetic mutations in HCN channels are associated with cardiac arrhythmias. In this study, we performed in-depth evolutionary analyses of HCN channels and functionally characterized the biophysical properties of two novel HCN clones (ciHCNa and ciHCNb) from the urochordate, Ciona intestinalis; a species emerging at the pivotal evolutionary period of invertebrate and vertebrate divergence that occurred approximately 550MYA. We have expanded the list of known HCN sequences by identifying and annotating 31 novel genes from invertebrates, urochordates, fish, amphibians, birds, and mammals. Our data suggest that the four vertebrate HCN isoforms arose via three duplication and diversification events from a single ancestral gene following the divergence of urochordates. Functional analyses of the two ciHCN channels further support this evolutionary trajectory, suggesting that the common single HCN ancestor of urochordates and vertebrates had a mammalian-like channel phenotype. Lineage-specific duplication and diversification events and 550MY of independent evolution has lead to two Ciona HCN channels with distinct biophysical properties. The voltage-gated potassium channels, HERG and KCNQ1, play a key role in cardiac repolarization. Mutations in these delayed rectifier channels are also associated with cardiac arrhythmias, including long QT syndrome and sudden death. Taking advantage of the >200 disease mutations in both of these channels, we performed the first quantitative evolutionary and chemical severity analysis of arrhythmia associated mutations (AAMs). Unlike non-synonymous polymorphisms (nsSNPs), AAMs are preferentially located to the evolutionarily conserved and functionally important sites and regions within HERG and KCNQ1. The mutations are also chemically more severe than changes which occur throughout evolution. In conjunction with previous studies, our findings suggest that novel disease-associated mutations can be identified by surveying the naturally occurring variation that exists among species. Overall, this thesis contributes to the current knowledge of the interdependent relationships that exist among ion channel evolution, ion channel function, and human disease.
Third Order Lagrangians, Weyl Invariants & Classical Trace Anomaly in Six Dimensions
Creators: name: Farhoudi, Mehrdad
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We have proceeded analogy of Einstein tensor and alternative form of Einstein field equations for generic coeffcients of eight terms in third order of Lovelock Lagrangian. We have found constraint between the coeffcients into two forms, an independent and a dimensional dependent versions. Each form has three degrees of freedom, and not only the exact coeffcients of third order Lovelock Lagrangian satisfy the two forms of constraints, also the two independent cubic of Weyl tensor satisfy the independent constraint in six dimensions and yield the dimensional dependent version identically independent of dimension. We have introduced most general effective expression for a total third order type Lagrangian with the homogeneity degree number three which includes the previous eight terms plus new three ones among all seventeen independent terms. We have proceeded analogy for this combination, and have achieved relevant constraint. We have shown that expressions given in literature as third Weyl invariant combination in six dimensions satisfy this constraint. Thus, we suggest that these constraint relations to be considered as the necessary consistency conditions on the numerical coeffcients that a Weyl invariant in six dimensions should satisfy. We have calculated the "classical" trace anomaly (an approach that was presented in our previous works) for introduced total third order type Lagrangian and have achieved general expression with four degrees of freedom in more than six dimensions. We have demonstrated that resulted expression contains exactly relevant coeffcient of Schwinger-DeWitt proper time method (linked with relevant heat kernel coeffcient) in six dimensions, as a particular case. Our approach can be regarded as alternative derivation of trace anomaly which also gives general expression with the relevant degrees of freedom.
description: 26 pages, appendix and references added
Bimetric Gravity from Ghost-free Massive Gravity
Creators: name: Hassan, S. F.
name: Rosen, Rachel A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Generically, non-linear bimetric theories of gravity suffer from the same Boulware-Deser ghost instability as non-linear theories of massive gravity. However, recently proposed theories of massive gravity have been shown to be ghost-free. These theories are formulated with respect to a flat, non-dynamical reference metric. In this work we show that it is possible to give dynamics to the reference metric in such a way that the consistency of the theory is maintained. The result is a non-linear bimetric theory of a massless spin-2 field interacting with a massive spin-2 field that is free of the Boulware-Deser ghost. To our knowledge, this is the first construction of such a ghost-free bimetric theory.
description: results extended, version accepted for publication
Degrees of Freedom in Massive Gravity
Creators: name: Comelli, D.
name: Crisostomi, M.
name: Nesti, F.
name: Pilo, L.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study in a systematic way a generic nonderivative (massive) deformation of general relativity using the Hamiltonian formalism. The number of propagating degrees of freedom is analyzed in a nonperturbative and background independent way. We show that the condition of having only five propagating degrees of freedom can be cast in a set of differential equations for the deforming potential. Though the conditions are rather restrictive, many solutions can be found.
description: 5 pages. Final version published in PRD rapid communications
The Validity of New Memory Complaints in the Elderly
Creators: name: Schofield, Peter R. W.
name: Jacobs, Diane
name: Marder, Karen
name: Sano, Mary
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 1997
Subjects: Neurology
Memory in old age
Older people
Cognition

description: Objective: To determine the validity of new subjective memory complaints (MCs) from individuals who previously, when without dementia, denied having MCs. Design: Prospective cohort. Setting: Longitudinal, community-based study of aging and dementia. Patients: One hundred thirty-three communitydwelling elderly individuals who were part of a registry for the study of conditions related to aging in North Manhattan, NY. Patients were selected if they were initially without dementia and had completed at least 2 successive annual clinical and neuropsychological evaluations and provided their own medical history. Main Outcome Measures: Performance on memory tests—the Buschke Selective Reminding Test and a visual memory task—and global performance on a neuropsychological test battery and clinical evaluation, by which questionable dementia or dementia was diagnosed according to a well-defined paradigm. Results: Fifty-three subjects with MCs at the initial evaluation performed no worse on the memory test than the 80 subjects who denied MCs initially. There was a weak association between MCs and the diagnosis of questionable dementia at baseline (P=.04), but this was nonsignificant after adjusting for age and education. At 1-year follow-up, 21 of the 80 without baseline MCs now reported MCs. At the follow-up evaluation, these 21 subjects performed significantly worse on the memory tests, were 5 times more likely to have significant cognitive impairment, and had shown significantly greater decline over the preceding year on several of the cognitive measures than the 59 who continued to deny MCs. Conclusion: New MCs from individuals, who when without dementia recently denied MCs, may suggest the presence of significant impairment of memory or cognition.
The Third Gerald Dunning Lecture. Three Aspects of the Wheel-Turned Pottery of Dorestad: A Synopsis
Creators: name: Van Es, WA
name: Bardet, AC
name: Verwers, WJH
Publisher: name: Archaeology Data Service
Year: 2023

description: Medieval Ceramics: Journal of the Medieval Ceramics Research Group, 8, 3-10
description: German Rhineland and found in the Netherlands, with particular reference to the finds from Dorestad. The subject was divided into three parts: 1. the composition of the pottery complex found at Dorestad itself; 2. the physical and chemical research into the provenance of the wheel-made wares occurring on that site; 3. the distribution pattern of these wares over the Netherlands and the role which Dorestad played in the distribution of Rhenish pottery.
Roulette Ware
Creators: name: Gelichi, Sauro
Publisher: name: Archaeology Data Service
Year: 2023

description: Medieval Ceramics: Journal of the Medieval Ceramics Research Group, 8, 47-58
description: The article discusses a type of bowl form characterised by rouletted decoration on the exterior which has been found in Greece and in Italy. Morgan, who first drew attention to this pottery, defined it as a type and called it Roulette Ware, dating it to the Turkish period. Stillwell Mackay studied the group further and dated it to the 13th-14th century. It seems, in fact, that Roulette Ware is not a discrete pottery type but a form of decoration which occurs on a number of vessels (glazed, slipped, painted, sgraffito). The production centre is thought to be Italian rather than Byzantine. The presence of kiln wasters and results from mineralogical analysis suggests a centre around Venice. The chronology proposed by Stillwell Mackay has been confirmed by the dating of bacini and discoveries from excavations in north-eastern Italy.
Collisions of charged black holes
Creators: name: Zilhão, Miguel
name: Cardoso, Vitor
name: Herdeiro, Carlos
name: Lehner, Luis
name: Sperhake, Ulrich
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We perform fully non-linear numerical simulations of charged-black-hole collisions, described by the Einstein-Maxwell equations, and contrast the results against analytic expectations. We focus on head-on collisions of non-spinning black holes, starting from rest and with the same charge to mass ratio, Q/M. The addition of charge to black holes introduces a new interesting channel of radiation and dynamics, most of which seem to be captured by Newtonian dynamics and flat-space intuition. The waveforms can be qualitatively described in terms of three stages; (i) an infall phase prior to the formation of a common apparent horizon; (ii) a nonlinear merger phase which corresponds to a peak in gravitational and electromagnetic energy; (iii) the ringdown marked by an oscillatory pattern with exponentially decaying amplitude and characteristic frequencies that are in good agreement with perturbative predictions. We observe that the amount of gravitational-wave energy generated throughout the collision decreases by about three orders of magnitude as the charge-to-mass ratio Q/M is increased from 0 to 0.98. We interpret this decrease as a consequence of the smaller accelerations present for larger values of the charge. In contrast, the ratio of energy carried by electromagnetic to gravitational radiation increases, reaching about 22% for the maximum Q/M ratio explored, which is in good agreement with analytic predictions.
description: 15 pages, 8 figures; v2: improved one plot and other minor changes. matches published version in PRD
The Response-Signal Method Reveals Age-Related Changes in Object Working Memory
Creators: name: Kumar, Arjun
name: Rakitin, Brian C.
name: Nambisan, Rohit
name: Habeck, Christian G.
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Psychology
subject: FOS: Psychology
subject: Aging
subject: Short-term memory
subject: Memory--Age factors

description: Sixteen healthy young adults (ages 18-32) and 16 healthy older adults (ages 67-81) completed a delayed response task in which they saw the following visual sequence: memory stimuli (2 abstract shapes; 3,000 ms), a blank delay (5,000 ms), a probe stimulus of variable duration (one abstract shape; 125, 250, 500, 1,000, or 2,000 ms), and a mask (500 ms). Subjects decided whether the probe stimulus matched either of the memory stimuli; they were instructed to respond during the mask, placing greater emphasis on speed than accuracy. The authors used D. L. Hintzman & T. Curran's (1994) 3-parameter compound bounded exponential model of speed-accuracy tradeoff to describe changes in discriminability associated with total processing time. Group-level analysis revealed a higher rate parameter and a higher asymptote parameter for the young adult group, but no difference across groups in x-intercept. Proxy measures of cognitive reserve (Y. Stern et al., 2005) predicted the rate parameter value, particularly in older adults. Results suggest that in working memory, aging impairs both the maximum capacity for discriminability and the rate of information accumulation, but not the temporal threshold for discriminability.
A Preliminary Note on a Late Saxon Ware from Nottingham
Creators: name: Nailor, Victoria
Publisher: name: Archaeology Data Service
Year: 2023

description: Medieval Ceramics: Journal of the Medieval Ceramics Research Group, 8, 59-64
description: Material from a recent excavation in Nottingham included a group of late Saxon pottery from possibly the stoke-pit of a pottery kiln. Some of the features normally associated with wasters are present. The most common form is the cooking pot/jar, with a small number of wide-mouthed bowls and one or two storage vessels. The provisional date range for this ware is c. 920-1020 on ceramic grounds, with argument for a date c. 1000. It is proposed to call this pottery 'Nottingham ware'.
Unir les forces pour accélérer le changement - Joining Forces to Accelerate Change
Creators: name: Niemann, Tanja
Publisher: name: Zenodo
Year: 2021

description: Coalition Publica est une initiative commune de deux projets basés au Canada, Érudit (erudit.org) et le Public Knowledge Project (PKP), qui collaborent pour développer et coordonner une infrastructure nationale ouverte et durable soutenant la diffusion de la recherche et l'édition scientifique numérique.
 L'effort de collaboration vise l’atteinte d'objectifs communs : renforcer les capacités locales et l'expertise en édition dans le but de soutenir les revues en sciences humaines et sociales en anglais et en français. Grâce à un modèle financier basé sur des partenariats avec des bibliothèques, des agences gouvernementales, des universités et d'autres institutions connexes, Coalition Publica encourage une transition juste et durable vers le libre accès.
 Les principes de diversité, d’équité et d’inclusion sont au cœur du mandat de Coalition Publica. Cependant, atteindre ces principes exige des efforts concertés et continus. Cette présentation propose une brève auto-évaluation afin de discuter de nos bons coups et de ce qui peut encore être amélioré en termes de principes EDI. -------------- Coalition Publica is a joint partnership initiative of two key Canadian-based projects, Érudit (erudit.org) and the Public Knowledge Project (PKP), collaborating to develop and coordinate an open and sustainable national infrastructure supporting research dissemination and digital scholarly publishing.
 The collaborative effort aims to achieve a purpose common to both entities: build local capacity and publishing expertise to support humanities and social sciences journals either in English or in French. Through a financial model based on partnerships with libraries, government agencies, universities, and other related institutions, Coalition Publica encourages a fair and sustainable transition to open access.
 Diversity, equity and inclusion principles are at the heart of Coalition Publica’s mandate. However, reaching those principles requires concerted and continuous efforts. This presentation will offer a short self-assessment to discuss what we do well and what can still be improved with regards to EDI principles.
The Aggregation Kinetics of a Simulated Telechelic Polymer
Creators: name: Wilson, Mark
name: Rabinovitch, Avinoam
name: Baljon, Arlette R. C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We investigate the aggregation kinetics of a simulated telechelic polymer gel. In the hybrid Molecular Dynamics (MD) / Monte Carlo (MC) algorithm, aggregates of associating end groups form and break according to MC rules, while the position of the polymers in space is dictated by MD. As a result, the aggregate sizes change every time step. In order to describe this aggregation process, we employ master equations. They define changes in the number of aggregates of a certain size in terms of reaction rates. These reaction rates indicate the likelihood that two aggregates combine to form a large one, or that a large aggregate splits into two smaller parts. The reaction rates are obtained from the simulations for a range of temperatures. Our results indicate that the rates are not only temperature dependent, but also a function of the sizes of the aggregates involved in the reaction. Using the measured rates, solutions to the master equations are shown to be stable and in agreement with the aggregate size distribution, as obtained directly from simulation data. Furthermore, we show how temperature induced variations in these rates give rise to the observed changes in the aggregate distribution that characterizes the sol-gel transition.
description: 9 pages, 10 figures
Toward Defining the Preclinical Stages of Alzheimer's Disease: Recommendations from the National Institute on Aging-Alzheimer's Association Workgroups on Diagnostic Guidelines for Alzheimer's Disease
Creators: name: Sperling, Reisa A.
name: Aisen, Paul S.
name: Beckett, Laurel A.
name: Bennett, David A.
name: Craft, Suzanne
name: Fagan, Anne M.
name: Iwatsubo, Takeshi
name: Jack Jr., Clifford R.
name: Kaye, Jeffrey
name: Montine, Thomas J.
name: Park, Denise C.
name: Reiman, Eric M.
name: Rowe, Christopher C.
name: Siemers, Eric
name: Stern, Yaakov
name: Yaffe, Kristine
name: Carrillo, Maria C.
name: Thies, Bill
name: Morrison-Bogorad, Marcelle
name: Wagster, Molly V.
name: Phelps, Creighton H.
Publisher: name: Columbia University
Year: 2011
Subjects: Alzheimer's disease--Pathophysiology
Biochemical markers
Medical sciences
Amyloid

description: The pathophysiological process of Alzheimer's disease (AD) is thought to begin many years before the diagnosis of AD dementia. This long "preclinical" phase of AD would provide a critical opportunity for therapeutic intervention; however, we need to further elucidate the link between the pathological cascade of AD and the emergence of clinical symptoms. The National Institute on Aging and the Alzheimer's Association convened an international workgroup to review the biomarker, epidemiological, and neuropsychological evidence, and to develop recommendations to determine the factors which best predict the risk of progression from "normal" cognition to mild cognitive impairment and AD dementia. We propose a conceptual framework and operational research criteria, based on the prevailing scientific evidence to date, to test and refine these models with longitudinal clinical research studies. These recommendations are solely intended for research purposes and do not have any clinical implications at this time. It is hoped that these recommendations will provide a common rubric to advance the study of preclinical AD, and ultimately, aid the field in moving toward earlier intervention at a stage of AD when some disease-modifying therapies may be most efficacious.
title: The Darmstadt Energy Laboratory for Technologies in Application: Overview Paper – Living Lab DELTA
Creators: name: Kohne, Thomas
name: Beck, Martin
name: Bishara, Nadja
name: Seyfried, Stefan
name: Schneider, Jens
name: Weigold, Matthias
name: Weigold, Matthias
name: Kohne, Thomas
name: Seyfried, Stefan
name: Beck, Martin
name: Bishara, Nadja
name: Technische Universtität Darmstadt
Publisher: name: UNSPECIFIED
Year: 2023

description: In the living lab DELTA, energy system methods are applied, and energy technology systems are installed to transfer successful pilot projects of the urban energy transition to a broad application. The focus is on the consistent improvement of energy efficiency in all sectors, which is already considered to be the largest usable potential of the urban energy transition. In addition, the potential for shifting electrical loads over time to optimize the integration of renewable energy sources will be identified. Energy efficiency and flexibility will be achieved by intelligently linking individual districts of the urban energy system and by sector coupling. The development of a holistic innovation ecosystem is essential to enable all stakeholders in the energy system to participate in the energy and economic potential. To this end, the project pursues a multi-level, cross-sectoral approach.
What is the limit $\hbar \to 0$ of quantum theory ?
Creators: name: Klein, U.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: An analysis is made of the relation between quantum theory and classical mechanics, in the context of the limit $\hbar \to 0$. Several ways in which this limit may be performed are considered. It is shown that Schrödinger's equation for a single particle moving in an external potential $V$ does not, except in special cases, lead, in this limit, to Newton's equation of motion for the particle. This shows that classical mechanics cannot be regarded as emerging from quantum mechanics-at least in this sense-upon straightforward application of the limit $\hbar \to 0$.
description: 12 pages, no figures
Calculating energy storage due to topological changes in emerging active region NOAA AR 11112
Creators: name: Tarr, L. A.
name: Longcope, D. W.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The Minimum Current Corona (MCC) model provides a way to estimate stored coronal energy using the number of field lines connecting regions of positive and negative photospheric flux. This information is quantified by the net flux connecting pairs of opposing regions in a connectivity matrix. Changes in the coronal magnetic field, due to processes such as magnetic reconnection, manifest themselves as changes in the connectivity matrix. However, the connectivity matrix will also change when flux sources emerge or submerge through the photosphere, as often happens in active regions. We have developed an algorithm to estimate the changes in flux due to emergence and submergence of magnetic flux sources. These estimated changes must be accounted for in order to quantify storage and release of magnetic energy in the corona. To perform this calculation over extended periods of time, we must additionally have a consistently labeled connectivity matrix over the entire observational time span. We have therefore developed an automated tracking algorithm to generate a consistent connectivity matrix as the photospheric source regions evolve over time. We have applied this method to NOAA Active Region 11112, which underwent a GOES M2.9 class flare around 19:00 on Oct.16th, 2010, and calculated a lower bound on the free magnetic energy buildup of ~8.25 x 10^30 ergs over 3 days.
description: 36 pages, 14 figures. Published in 2012 ApJ, 749, 64. Published version available at http://stacks.iop.org/0004-637X/749/64 Animation available at http://solar.physics.montana.edu/tarrl/data/AR11112.mp4
¿Qué tipo de diversidad, inclusión y colaboración? Redefiniendo los valores de la comunicación científica desde las Humanidades Digitales - What diversity, inclusion and collaboration? (Re)defining the values of Scholarly Communication from the Digital Humanities
Creators: name: del Rio Rande, Gimena
Publisher: name: Zenodo
Year: 2021

description: Junto con las innovadores metodologías y prácticas digitales y computacionales, las Humanidades Digitales proponen nuevos modelos de trabajo, publicación y evaluación. Si bien los debates sobre los valores y la ética del trabajo en las Humanidades Digitales tienen una larga data en las academias anglófonas interesadas en el campo, en América Latina han surgido formas de repensar las Humanidades Digitales desde los movimientos de acceso abierto y ciencia abierta. Valores como la diversidad, la inclusión y la colaboración se han visto así beneficiados por nuevas aproximaciones teóricas y la puesta en práctica a través de diferentes recursos y herramientas digitales del ámbito de la comunicación científica. --------------
 The Digital Humanities propose innovative digital and computational methodologies and practices, together with new approaches to research, publication and evaluation. Although debates about the values of the Digital Humanities have a long history in Northern academies, Latin America has been more interested in rethinking the Digital Humanities from open access and open science movements. Values such as diversity, inclusion and collaboration have thus been benefited by new theoretical approaches and implementation through different scholarly communication resources and digital tools.
Measuring and Responding to Income Poverty
Creators: name: Kneebone, Ronald
name: Wilkins, Margarita
Publisher: name: The School of Public Policy Publications
Year: 2019

description: This paper discusses and describes measures of poverty and, on the basis of that discussion, proposes a public policy response that more closely and more easily targets income support to where it is most needed and most effective. Our review of poverty measures shows there are many holes that prevent advocates and policy-makers from obtaining a clear picture of who is in poverty and the depth of that poverty. The Market Basket Measure is the most finely tuned to identifying where impoverished families live and that is in large part why it was recently adopted by the federal government to gauge its anti-poverty policies. The government of Alberta, on the other hand, evaluates its policies using a measure of poverty that allows no consideration that costs of living might vary by community. Social assistance is the main policy instrument through which the federal and provincial governments provide assistance to people in need. We show that the growing emphasis of increasing social-assistance support via child benefits provides no increase in support in what has been for some time the majority of social-assistance cases. What’s more, despite a great deal of evidence that the cost of meeting basic needs varies widely by community, the amount of assistance provided is the same regardless of where one lives in the province. We propose a modification to how social assistance is provided that makes allowances for the fact poverty is deeper in some parts of the province than others and that provides support to individuals and families whether or not they have children. Our proposal is superior to rent control as a means of dealing with falling housing affordability, removes barriers to people receiving social assistance from moving to seek employment, and has features similar to a guaranteed basic income. It is also inexpensive. We estimate the cost of our proposal to be equivalent to less than one per cent of the provincial health-care budget.
description: The School of Public Policy Publications, Vol 12 (2019)
Vapnik-Chervonenkis density in some theories without the independence property, II
Creators: name: Aschenbrenner, M.
name: Dolich, A.
name: Haskell, D.
name: Macpherson, D.
name: Starchenko, S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Logic (math.LO)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: We study the Vapnik-Chervonenkis (VC) density of definable families in certain stable first-order theories. In particular we obtain uniform bounds on VC density of definable families in finite U-rank theories without the finite cover property, and we characterize those abelian groups for which there exist uniform bounds on the VC density of definable families.
description: 53 pp
Supplementary Electronic Material from Human growth factor-mediated signalling through lipid rafts regulates stem cell proliferation, development and survival of Schistosoma mansoni
Creators: name: Maharjan, Shradha
name: Kirk, Ruth S.
name: Lawton, Scott P.
name: Walker, Anthony J.
Publisher: name: The Royal Society
Year: 2023
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310404
subject: Evolution of developmental systems
classificationCode: 310799
subject: Microbiology not elsewhere classified

description: Supplementary data for: Human growth factor-mediated signalling through lipid rafts regulates stem cell proliferation, development, and survival of Schistosoma mansoni
title: Comparison of the effects of climate variations on pelagic ocean habitats and their potential role in structuring the forage fish distributions in the Bering Sea and Gulf of Alaska
Creators: name: Hollowed, Anne B.
name: Barbeaux, Steven
name: Farley, Ed
name: Cokelet, Ned
name: Kotwicki, Stan
name: Logerwell, Elizabeth
name: Ressler, Patrick
name: Wilson, Christopher
Publisher: name: ASC 2010 - Theme session R
Year: 2024
Subjects: Pressures, impacts, conservation, and management

description: No abstracts are to be cited without prior reference to the author.Theoretical ecology suggests that competition between species and predator-prey interactions are modulated by the quality and quantity of suitable habitat. This paper examines whether climate variations influence the boundaries of suitable pelagic habitat, and whether these changes effect the spatial distribution and interactions between key fish species in the Bering Sea and Gulf of Alaska. The study focuses on the summer distributions of forage fish (age-0 and age-1 walleye pollock (Theragra chalcogramma), and capelin, (Mallotus villous). Forage fish distributions were collected during summer acoustic and bottom trawl surveys conducted as part of the NOAA groundfish trawl and acoustic surveys in the Bering Sea in 2003 -2007, and the NOAA Fishery Interaction Team experiments in the Gulf of Alaska conducted in 2000-2006. We compare the responses of age-0 and age-1 walleye pollock, and capelin to climate induced shifts in pelagic habitats in the Bering Sea and Gulf of Alaska ecosystems. Habitat boundaries are defined using key explanatory variables including: forage fish density, predator distribution, depth, bottom temperature, surface temperature, and surface chlorophyll a. General Linear Models are developed to predict the spatial distribution of age-0 pollock, age-1 pollock and capelin in both regions. Comparison of the responses of three classes of forage fish in different ecosystems helps to better understand their expected responses to climate forcing.
The Relation of Patient Dependence to Home Health Aide Use in Alzheimer's Disease
Creators: name: Scherer, Rachel K.
name: Scarmeas, Nikolaos
name: Brandt, Jason
name: Blacker, Deborah
name: Albert, Marilyn S.
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 2008
Subjects: Neurology
Alzheimer's disease--Patients--Home care
Home care services
Gerontology

description: BACKGROUND: Although there has been much research devoted to understanding the predictors of nursing home placement (NHP) in Alzheimer's disease (AD) patients, there is currently a lack of research concerning the predictors of home health care. The objective of this study was to examine whether the Dependence Scale can predict home health aide (HHA) use. METHODS: The sample is drawn from the Predictors Study, a large, multicenter cohort of patients with probable AD, prospectively followed annually for up to 7 years in three university-based AD centers in the United States. Markov analyses (n=75) were used to calculate annual transition probabilities for the "new onset" of HHA use (instances where an HHA was absent at the previous visit, but present at the next visit) as a function of HHA presence at the preceding year's visit and dependence level at that preceding year's visit. RESULTS: The dependence level at the previous year's visit was a significant predictor of HHA use at the next year's visit. Three specific items of the Dependence Scale (needing household chores done for oneself, needing to be watched or kept company when awake, and needing to be escorted when outside) were significant predictors of the presence of an HHA. CONCLUSION: The Dependence Scale is a valuable tool for predicting HHA use in AD patients. Obtaining a better understanding of home health care in AD patients may help delay NHP and have a positive impact on the health and well-being of both the caregiver and the patient.
Charmonium production from nonequilibrium charm and anticharm quarks in quark-gluon plasma
Creators: name: Song, Taesoo
name: Han, Kyong Chol
name: Ko, Che Ming
Publisher: name: arXiv
Year: 2012
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Parameterizing the charm and anticharm quark momentum distributions by the Tsallis distribution, we study the nonequilibrium effect on the charmonium production rate in a quark-gluon plasma up to the next-to-leading order in perturbative QCD. We find that nonequilibrium charm and anticharm quarks suppress the charmonium production rate compared to that from equilibrated ones. We further show that the suppression factor calculated with the charm quark relaxation time, which has been frequently used in the literature, is close to our results.
description: 8 pages, 5 figures
New solid state laser crystals created by epitaxial growth
Creators: name: Kumaran, Raveen
Publisher: name: University of British Columbia
Year: 2012

description: Rare-earth-doped oxide crystals such as Nd:YAG are often used as the gain medium in solid state lasers because they produce a collection of sharp emission peaks, some of which have strong gain. Rather than the typical bulk form of these crystals, thin films with planar waveguide geometry are promising alternatives for compact devices with lower lasing thresholds and better heat extraction. Such benefits motivated the growth of these oxide films by molecular beam epitaxy, a technique capable of films with precise composition, thickness and structure due to its independently controlled elemental sources. Two sets of material systems were attempted, Al-Ga-O and Y-Al-O, with Nd as the sole dopant. The films were grown on sapphire substrates of various orientations, then analyzed by x-ray diffraction and photoluminescence where peaks signaled long-range and short-range order respectively. Work on the Al-Ga-O system yielded Nd:α-Al₂O₃ (Nd:sapphire) and Nd:α-Ga₂O₃, two new laser crystals with unique collections of sharp emission peaks only observable from single-crystal films grown at temperatures far below the melting point. These conditions were required to confine the much-larger Nd dopants into Al and Ga sites with short-range order, and are unlikely reproducible by bulk methods. Due to their shared corundum structure, the emission spectra from Nd:sapphire and Nd:α-Ga₂O₃ appear similar but wavelength-shifted. The dominant Nd:sapphire peak has strong gain comparable to its counterpart from Nd:YVO₄, one of the highest available, while the blue-shifted Nd:α-Ga₂O₃ peak is likewise comparable to Nd:YAG. Alloying both produced corundum-structure crystals with peaks that shifted linearly with unit cell volume, which in turn depended on Ga/Al ratio and film stress. These Al-Ga-O crystals are promising for applications involving compositional-tuning and graded-index layers. Ternary Y-Al-O is not tunable because it has three stable phases YAM, YAP and YAG with different compositions, structures and thus emission spectra. Single-phase films of each phase were grown without single-crystal structure but still yielded sharp peaks consistent with their bulk counterparts. Short-range order was achievable because the Nd dopants were size-compatible with the Y sites. While the peaks did not shift with Y/Al ratio, peak sharpness improved when the ratio approached bulk stoichiometric values.
Data-driven density derivative estimation, with applications to nonparametric clustering and bump hunting
Creators: name: Chacón, José E.
name: Duong, Tarn
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistics Theory (math.ST)
subject: Methodology (stat.ME)
subject: Machine Learning (stat.ML)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 62G05, 62H30

description: Important information concerning a multivariate data set, such as clusters and modal regions, is contained in the derivatives of the probability density function. Despite this importance, nonparametric estimation of higher order derivatives of the density functions have received only relatively scant attention. Kernel estimators of density functions are widely used as they exhibit excellent theoretical and practical properties, though their generalization to density derivatives has progressed more slowly due to the mathematical intractabilities encountered in the crucial problem of bandwidth (or smoothing parameter) selection. This paper presents the first fully automatic, data-based bandwidth selectors for multivariate kernel density derivative estimators. This is achieved by synthesizing recent advances in matrix analytic theory which allow mathematically and computationally tractable representations of higher order derivatives of multivariate vector valued functions. The theoretical asymptotic properties as well as the finite sample behaviour of the proposed selectors are studied. {In addition, we explore in detail the applications of the new data-driven methods for two other statistical problems: clustering and bump hunting. The introduced techniques are combined with the mean shift algorithm to develop novel automatic, nonparametric clustering procedures which are shown to outperform mixture-model cluster analysis and other recent nonparametric approaches in practice. Furthermore, the advantage of the use of smoothing parameters designed for density derivative estimation for feature significance analysis for bump hunting is illustrated with a real data example.
description: 36 pages, 5 figures
Probing the Rosette Nebula Stellar Bubble with Faraday Rotation
Creators: name: Savage, Allison H.
name: Spangler, Steven R.
name: Fischer, Patrick D.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report the results of Faraday rotation measurements of 23 background radio sources whose lines of sight pass through or close to the Rosette Nebula. The Rosette Nebula is an excellent candidate for studies of super bubbles associated with young star clusters. We made linear polarization measurements with the Karl G. Jansky Very Large Array (JVLA) at frequencies of 4.4GHz, 4.9GHz, and 7.7GHz. We are able to establish a background rotation measure in this part of the sky due to the Galaxy of +147 rad m^-2. Sources whose lines of sight pass through the nebula have an excess rotation measure of 50-750 rad m^-2, which we attribute to the plasma shell of the Rosette Nebula. We consider two simple plasma shell models and how they reproduce the magnitude and sign of the rotation measure, and its dependence on distance from the center of the nebula. These two models represent different modes of interaction of the Rosette Nebula star cluster with the surrounding interstellar medium. Both can reproduce the magnitude and spatial extent of the rotation measure enhancement, given plausible free parameters. We contend that the model based on a stellar bubble more closely reproduces the observed dependence of rotation measure on distance from the center of the nebula.
description: 10 figures