cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Логика
title: Учебное пособие
titleType: Subtitle
Creators: name: Довгаленко Н.В.
name:  Ромащенко А.А.
name:  Ромащенко М.А.
Publisher: name: Саратовский государственный технический университет имени Ю.А. Гагарина, ЭБС АСВ
Year: 2014

description: Учебное пособие включает в себя целый учебно-методический комплекс, в который входят конспект лекций, охватывающий основные темы формальной логики, практические задания и глоссарий. Кроме основных разделов формальной логики в пособие включена глава, посвященная истории логических учений. Учебное пособие предназначено для студентов, изучающих курс «Логика» и для широкого круга читателей, интересующихся основами логического мышления.
description: The textbook includes a whole educational-methodical complex, which includes lecture notes covering the main topics of formal logic, practical exercises, and a Glossary. In addition to the main sections of formal logic, the manual includes a Chapter on the history of logical doctrines. The textbook is designed for students studying a course "Logic" and wide circle of readers interested in the basics of logical thinking.
title: Assessment of the adequacy of the coronary CT scan requests at the Emergency Department
Creators: name: García de Pereda De Blas, Verónica
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Emergency
subject: CT
subject: Efficacy studies

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: We evaluate the appropriateness criteria of the requests and the results of the coronary CT scans performed in the Emergency Department (ED) of our...
Clinical Implications of Complex Pharmacokinetics for Daratumumab Dose Regimen in Patients With Relapsed/Refractory Multiple Myeloma
Creators: name: Puchalski,
name: Ruixo, JJ Perez
name: Plesner,
name: Khan,
name: Lonial,
name: Clemens,
name: Yan,
name: Liu,
name: Jansson,
name: Zhou,
name: Lokhorst,
name: Ahmadi,
name: Xu,
name: Voorhees,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: New therapeutic strategies are urgently needed to improve clinical outcomes in patients with multiple myeloma (MM). Daratumumab is a first‐in‐class, CD38 human immunoglobulin G1κ monoclonal antibody approved for treatment of relapsed or refractory MM. Identification of an appropriate dose regimen for daratumumab is challenging due to its target‐mediated drug disposition, leading to time‐ and concentration‐dependent pharmacokinetics. We describe a thorough evaluation of the recommended dose regimen for daratumumab in patients with relapsed or refractory MM.
Criticality and correlated dynamics at the irreversibility transition in periodically driven colloidal suspensions
Creators: name: Tjhung, Elsen
name: Berthier, Ludovic
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: One possible framework to interpret the irreversibility transition observed in periodically driven colloidal suspensions is that of a non-equilibrium phase transition towards an absorbing reversible state at low amplitude of the driving force. We consider a simple numerical model for driven suspensions which allows us to characterize in great detail a large body of physical observables that can be experimentally determined to assess the existence and universality class of such a non-equilibrium phase transition. Characterizing the behaviour of static and dynamic correlation functions both in real and Fourier space we determine in particular several critical exponents for our model, which take values that are in good agreement with the universality class of direct ed percolation. We also provide a detailed analysis of single-particle and collective dynamics of the system near the phase transition, which appear intermittent and spatially correlated over diverging timescales and lengthscales, and provide clear signatures of the underlying criticality.
description: 27 pages, 12 figures; J. Stat. Mech. (in press)
Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials
Creators: name: Siler,
name: Generaux,
name: Mosedale,
name: Eisen,
name: Button,
name: Iaci,
name: Stanulis,
name: Parry,
name: Howell,
name: Watkins,
name: Longo,
name: Caggiano,
name: Antoine,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Cimaglermin alfa (GGF2) is a recombinant human protein growth factor in development for heart failure. Phase I trials were suspended when two cimaglermin alfa‐treated subjects experienced concomitant elevations in serum aminotransferases and total bilirubin, meeting current US Food and Drug Administration criteria for a serious liver safety signal (i.e., “Hy's Law”). We assayed mechanistic biomarkers in archived clinical trial serum samples which confirmed the hepatic origin of the aminotransferase elevations in these two subjects and identified apoptosis as the major mode of hepatocyte death. Using a mathematical model of drug‐induced liver injury (DILIsym) and a simulated population, we estimated that the maximum hepatocyte loss in these two subjects was <13%, which would not result in liver dysfunction sufficient to significantly increase serum bilirubin levels. We conclude that the two subjects should not be considered Hy's Law cases and that mechanistic biomarkers and modeling can aid in refining liver safety risk assessment in clinical trials.
Surface- and strain-tuning of the optical dielectric function in epitaxially grown CaMnO3
Creators: name: Imbrenda, Dominic
name: Yang, Dongyue
name: Wang, Hongwei
name: Akbashev, Andrew R.
name: Kasaei, Leila
name: Davidson, Bruce A.
name: Wu, Xifan
name: Xi, Xiaoxing
name: Spanier, Jonathan E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report a strong thickness dependence of the complex frequency-dependent optical dielectric function in epitaxial CaMnO3(001) thin films on SrTiO3(001), LaAlO3(001), and SrLaAlO4(001) substrates. A doubling of the peak value of the imaginary part of the dielectric function and spectral shifts of 0.5 eV for a given magnitude of absorption are observed. On the basis of the experimental data and first-principles density functional theory calculations of the dielectric function, its evolution with thickness from 4 to 63 nm has several regimes. In the thinnest, strain-coherent films, the response is characterized by a significant contribution from the free surface that dominates strain effects. However, at intermediate and larger thicknesses approaching the bulk-like film, strain coherence and partial strain relaxation persist and in influence the dielectric function.
description: 7 pages text, 16 pages total, 4 figures, 1 table
title: Hepatic encephalopathy after TIPS: time to improve the classification?
Creators: name: Discalzi, Andrea
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Interventional non-vascular
subject: Liver
subject: Abdomen
subject: Catheter venography
subject: Ultrasound-Colour Doppler
subject: Outcomes analysis
subject: Complications
subject: Shunts
subject: Cirrhosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Hepatic encephalopathy (HE) remains a significant problem after TIPS placement and represents an important drawback of this otherwise valuable and life- prolonging intervention. The purpose of our study is to evaluate the incidence of HE after TIPS...
title: Investigating biomarkers in Parkinson's disease using machine learning
Creators: name: Ameli, Ali
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: Genome-Wide Association Studies (GWAS) identify genetic variations in individuals affected with diseases such as Parkinson's disease (PD), whose allele or genotype frequencies are significantly different between the affected individuals and individuals who are free of the disease. GWAS data can be used to identify genetic variations associated with the disease of interest. However, GWAS datasets are extensive and contain many more Single Nucleotide Polymorphisms (SNPs pronounced “snips”) than individual samples. To address these challenges, we used Singular-Vectors Feature Selection (SVFS) and applied it to PD GWAS datasets. We discovered a group of SNPs that are potentially novel PD biomarkers as we found indirect links between them and PD in the literature but have not directly been associated with PD before. Direct association means that current literature directly links a SNP with PD; while an indirect link means that current literature suggests the involvement of a SNP in a disease other than PD but this other disease co-occurs with PD in a significant number of PD patients. These indirectly-linked SNPs open new potential lines of investigation. Directly-linked SNPs identified by our method are rs11248060, rs239748, rs999473, and rs2313982. One can see the full list of identified SNPs in Section 4.4.
Search for far-infrared variability of protoplanetary disks in the Cha I star-forming region
Creators: name: Fockter, Zoltán Péter
name: Ábrahám, Péter
name: Kóspál, Ágnes
name: Claes, R.A.B.
name: Manara, Carlo F.
name: Marton, Gábor
name: Weber, C.
Publisher: name: Zenodo
Year: 2022

description: The research of star formation is one of the most popular area of modern astrophysics. Nowadays, we can use ground-based and space-borne observatories to study Young Stellar Objects in different states of their evolution, their time-domain behaviour related to accretion process, and the connection between the stars and their circumstellar environment. The Chamaeleon I molecular cloud complex is one of the most famous star-forming regions, located at a distance of 190 pc. In our study we use photometric data to analyse the multi-wavelenght variability of eight T Tauri stars (CR Cha, CT Cha, Glass I, VW Cha, VZ Cha, WW Cha, WX Cha and XX Cha) in Cha I. Our aim is to determine the disk’s thermal response on changing irradiation by the central source, with special emphasis on the little known far-infrared flux variations of the outer disk. For our analysis, we performed a 4-epoch weekly monitoring of the 8 stars using the CTIO 1.3m optical – near-IR telescope, the VLT/ISAAC L- and M-band camera, and the Herschel Space Observatory at 70 and 160 micrometer. We looked for far-infrared flux changes and their correlation with the simultaneous variation of the stellar luminosity. Here, we present the first results, and perform a simply analytical modeling of the expected far-infrared variability using a two-layer disk model. The project provides some first hints on how the stellar radiation influences the large outer regions of the circumstellar disk.
description: {"references": ["Balog et al. (2013). https://arxiv.org/abs/1309.6099", "Ulrich Klaas et al. (2018). https://arxiv.org/abs/1712.08422", "\u00c1. K\u00f3sp\u00e1l et al. (2012). https://arxiv.org/abs/1204.3473", "C. F. Manara et al. (2017). https://arxiv.org/abs/1704.02842"]}
Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters
Creators: name: Howell,
name: Woodhead,
name: Battista,
name: Stahl,
name: Mettetal,
name: Siler,
name: Yang,
name: Watkins,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Elevations in serum bilirubin during drug treatment may indicate global liver dysfunction and a high risk of liver failure. However, drugs also can increase serum bilirubin in the absence of hepatic injury by inhibiting specific enzymes/transporters. We constructed a mechanistic model of bilirubin disposition based on known functional polymorphisms in bilirubin metabolism/transport. Using physiologically based pharmacokinetic (PBPK) model‐predicted drug exposure and enzyme/transporter inhibition constants determined in vitro, our model correctly predicted indinavir‐mediated hyperbilirubinemia in humans and rats. Nelfinavir was predicted not to cause hyperbilirubinemia, consistent with clinical observations. We next examined a new drug candidate that caused both elevations in serum bilirubin and biochemical evidence of liver injury in rats. Simulations suggest that bilirubin elevation primarily resulted from inhibition of transporters rather than global liver dysfunction. We conclude that mechanistic modeling of bilirubin can help elucidate underlying mechanisms of drug‐induced hyperbilirubinemia, and thereby distinguish benign from clinically important elevations in serum bilirubin.
Atualização do Plano de trabalho e estrutura analítica do projeto EAP/EAR - PARCIAL
Creators: name: Nova, Alan Zuanella Vila
name: Aranda, Alex
name: Sousa, Fernando Maciel Lima E
name: Hiago Pereira Kanashiro
name: Alves, Julio Sergio Fernandes
name: Rodrigues, Leandro Veloso
name: De Siqueira, Priscila Fatima Pinheiro
name: Moreira, Rosiane Aparecida
name: Thiago Oliveira Hoerlle
name: Equipe Da Algar TI Consultoria S/A
name: De Sousa Júnior, Rafael Timóteo
name: De Mendonça, Fábio Lúcio Lopes
name: Nze, Georges Daniel Amvame
name: De Oliveira Albuquerque, Robson
name: Giozza, William Ferreira
name: Da Silva, Alex Mendes Pacheco
name: Almeida, Allan Filipe
name: De Moura, Ana Beatrice Neubauer
name: Da Silva, Ana Paula Bernadi
name: Vale, Ana Paula Morais
name: Ayra De Avila Almeida
name: Caetano, Caio Henrique
name: De Souza, Carlos Eduardo Ramalho
name: Cleuber Santos Silva
name: De Oliveira, Diego Martins
name: De Oliveira, Felipe Barreto
name: Praciano, Flavio Garcia
name: De Araújo, Gabriel Ribeiro
name: Alves, Guilherme Batista Meneses
name: Hiago Pereira Kanashiro
name: Martins, Isaac Silva
name: Pinto, Ismael Ithalo Barbosa
name: Da Costa E Silva Garcia, João Paulo
name: Joao Paulo Pimentel
name: Johnan Nicholas Reed
name: Klainer Mateus Estrela Gomes
name: De Oliveira Bezerra, Kelly Santos
name: Morais, Leonardo Jorge França
name: Reinaldi, Letícia Ramos
name: Da Silva Barbosa, Lucas
name: Luiz Augusto Dos Santos Pires
name: Ramos, Marcos Tércio
name: Domingues, Maria Karoline
name: Alves, Maria Tereza Correa Pacheco
name: Marilia Do Nascimento T. Valentim
name: Gomes, Orlando Werbeth Dos Santos
name: Rodrigues, Paulo Henrique Batista
name: Machado, Paulo Lima
name: Phelipe Alan Almeida
name: Rodrigues, Priscila Batista
name: Da Silva Camoes, Renato Jose
name: Thiago Leite De Souza
name: Schultz, Valeria Simas
name: Wellington Domingos Neves
Publisher: name: Zenodo
Year: 2023

description: Desenvolvimento e inovação visam realizar um estudo de inovações tecnológicas, nas áreas de tecnologia da informação, com ênfase na interoperabilidade de sistemas, gestão corporativa, processos de gestão, gerência de redes e gestão de dados, para áreas estratégicas da CoordenaçãoGeral de Tecnologia da Informação (CGTI) da Procuradoria Geral da Fazenda Nacional – PGFN.
title: Role of pre-operative ultrasonography for tumour thickness evaluation in guiding management in patients with oral tongue squamous cell carcinoma
Creators: name: Nair, Anirudh
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Oncology
subject: Head and neck
subject: Ultrasound
subject: Screening
subject: Diagnostic procedure
subject: Staging
subject: Metastases
subject: Neoplasia
subject: Pathology

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To assess the statistical correlation between the tumor thickness (TT) by ultrasonography versus microscopic measurement To assess the predictive capacity of tumor thickness (TT) by ultrasound in detecting nodal metastasis. Background & Purpose of...
Holographic Renyi Entropies and Restrictions on Higher Derivative Terms
Creators: name: Pastras, Georgios
name: Manolopoulos, Dimitrios
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We perform a holographic calculation of the Entanglement Rényi entropy $S_q(μ,λ)$, for spherical entangling surfaces in boundary CFT's with Einstein-Gauss-Bonnet-Maxwell holographic gravitational duals. We find that for Gauss-Bonnet couplings $λ$, larger than a specific value, but still allowed by causality, a violation of an inequality that Rényi entropies must obey by definition occurs. This violation is related to the existence of negative entropy black holes and restricts the coefficient of the Gauss-Bonnet coupling in the bulk theory. Furthermore, we discover a distinction in the analytic structure of the analytic continuation of $S_q(μ,λ)$, between negative and non-negative $λ$, suggesting the existence of a phase transition.
description: 15 pages, 8 figures. Talk delivered at the Workshop on Quantum Fields and Strings of the 2014 Corfu Summer Institute; To appear in Proceedings of Science (Proceedings of the Corfu Summer Institute 2014 "School and Workshops on Elementary Particle Physics and Gravity", 3-21 September 2014 Corfu, Greece); This talk draws heavily from arXiv:1404.1309
title: Inter-observer agreement of semi-automated quantitative lesion analysis in breast diffusion-weighted imaging
Creators: name: Dijkstra, Hildebrand
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: MR-Diffusion/Perfusion
subject: Observer performance
subject: Technology assessment
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Diffusion-weighted imaging (DWI) of breast lesions is usually quantified using a mono-exponential model such as the apparent diffusion coefficient (ADC) or a bi-exponential model such as intravoxel incoherent motion (IVIM), the latter quantifying...
Enjoyment of high-intensity interval training in an overweight/obese cohort: a short report
Creators: name: Smith-Ryan, Abbie E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Exercise enjoyment has been shown to be important for adherence. Minimal data exist on enjoyment of intense exercise, especially in clinical populations. The purpose of this study was to evaluate enjoyment levels of overweight and obese subjects undergoing 3 weeks of high-intensity interval training. Forty-two generally healthy overweight and obese men and women (body mass index = 30·8 ± 4·8 kg × m−2) volunteered for this study. Exercise enjoyment was quantified using the Exercise Enjoyment Scale before and after each of nine total interval training sessions, over a three-week period. Heart rate and ratings of perceived exertion (RPE) were measured at the end of each interval and training session. There were no significant differences in enjoyment between training groups (P > 0·05). Exercise enjoyment improved significantly over the three-week training phase (P < 0·05). Enjoyment levels were relatively high to begin training: mean ± SD: 4·2 ± 1·0 out of a 7 point scale. Heart rate and RPE were significantly reduced (P < 0·05) from pre- (day 1) to post-training (day 9). High-intensity interval training may be an enjoyable form of exercise for overweight and obese men and women. Enjoyment levels may continue to increase following initial introduction to this type of training. Due to the small time demand and high enjoyment, interval training may be an effective exercise approach in a sedentary population.
title: The additional value of ADC and IVIM in dynamic contrast-enhanced MRI of the breast
Creators: name: Dorrius, Monique
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Breast
subject: Lung
subject: Abdomen
subject: MR-Diffusion/Perfusion
subject: MR-Spectroscopy
subject: Mammography
subject: CAD
subject: Computer Applications-Detection, diagnosis
subject: Biopsy
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To validate the diagnostic potential of quantitative DWI implemented after DCE-MRI in the workup of breast lesions ≥ 1 cm by applying semi-automated...
title: Can echo intensity obtained from ultrasonography images reflect muscle strength in the frail elderly population?
Creators: name: Mirón Mombiela, Rebeca
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Musculoskeletal soft tissue
subject: Ultrasound
subject: Physiological studies
subject: Epidemiology

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The main purpose of the present study was to investigate whether muscle quality based on echo intensity (EI) is associated with muscle strength and correlates with the risk of frailty among elderly outpatients. The especific objectives of the study...
title: Use of IV-contrast versus IV-and oral-contrast in the evaluation of abdominal pain on CT in the emergency department
Creators: name: Wasserman, Michael
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Emergency
subject: Abdomen
subject: Contrast agents
subject: CT
subject: PACS
subject: Contrast agent-intravenous
subject: Contrast agent-oral

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Abdominal pain is one of the most common presenting complaints of patients in the Emergency Department (ED), accounting for roughly 5% of ED visits. 1 The differential diagnosis for abdominal pain is extensive and the consequences of abdominal pain...
On the existence of regular and irregular outer moons orbiting the Pluto-Charon system
Creators: name: Michaely, Erez
name: Perets, Hagai B.
name: Grishin, Evgeni
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The dwarf planet Pluto is known to host an extended system of five co-planar satellites. Previous studies have explored the formation and evolution of the system in isolation, neglecting perturbative effects by the Sun. Here we show that secular evolution due to the Sun can strongly affect the evolution of outer satellites and rings in the system, if such exist. Although precession due to extended gravitational potential from the inner Pluto-Charon binary quench such secular evolution up to $a_{crit}\sim0.0035$ AU ($\sim0.09$ $R_{Hill}$ the Hill radius; including all of the currently known satellites), outer orbits can be significantly altered. In particular, we find that \emph{co-planar} rings and satellites should not exist beyond $a_{crit}$; rather, satellites and dust particles in these regions secularly evolve on timescales ranging between $10^{4}-10^{6}$ yrs, and quasi-periodically change their inclinations and eccentricities through secular evolution (Lidov-Kozai oscillations). Such oscillations can lead to high inclinations and eccentricities, constraining the range where such satellites (and dust particles) can exist without crossing the orbits of the inner satellites, or crossing the outer Hill stability range. Outer satellites, if such exist are therefore likely to be \emph{irregular} satellites, with orbits limited to be non-circular and/or highly inclined. These could be potentially detected and probed by the New-Horizon mission, possibly providing direct evidence for the secular evolution of the Pluto satellite system, and shedding new light on its origins.
description: Comments are welcome
Cascading effects of BPT for child internalizing problems and caregiver depression
Creators: name: Gonzalez, Michelle A.
name: Jones, Deborah J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Behavioral Parent Training (BPT) is the standard of care for early onset (3 to 8 years old) disruptive behavior disorders (DBDs). Preliminary evidence suggests that BPT may also produce cascading treatment effects for comorbid and interrelated symptomatology in children, primarily internalizing problems, as well as symptomatology in multiple systems of the family, including caregiver depressive symptomatology. What is less well understood, however, is why and how BPT functions to impact these multiple symptom clusters within and between family members. Accordingly, this manuscript aims to serve as a conceptual and theoretical consideration of the mechanisms through which BPT may produce generalized treatment effects among children with early onset DBDs and internalizing problems, as well as the psychosocial difficulties among their caregivers. It is our intention that the hypothesized mechanisms highlighted in this review may guide advances in clinical research, as well as assessment and practice.
Stability of skyrmion lattices and symmetries of quasi-two-dimensional chiral magnets
Creators: name: Güngördü, Utkan
name: Nepal, Rabindra
name: Tretiakov, Oleg A.
name: Belashchenko, Kirill
name: Kovalev, Alexey A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Recently, there has been substantial interest in realizations of skyrmions, in particular in 2D systems due to increased stability resulting from reduced dimensionality. A stable skyrmion, representing the smallest realizable magnetic texture, could be an ideal element for ultra-dense magnetic memories. Here, we use the most general form of the 2D free energy with Dzyaloshinskii-Moriya interactions constructed from general symmetry considerations reflecting the underlying system. We predict that skyrmion phase is robust and it is present even when the system lacks the in-plane rotational symmetry. In fact, the lowered symmetry leads to increased stability of vortex-antivortex lattices with four-fold symmetry and in-plane spirals, in some instances even in the absence of an external magnetic field. Our results relate different hexagonal and square cell phases to the symmetries of materials used for realizations of skyrmions. This will give clear directions for experimental realizations of hexagonal and square cell phases, and will allow engineering of skyrmions with unusual properties. We also predict striking differences in gyro-dynamics induced by spin currents for isolated skyrmions and for crystals where spin currents can be induced by charge carriers or by thermal magnons. We find that under certain conditions, isolated skyrmions can move along the current without a side motion which can have implications for realizations of magnetic memories.
description: 14 pages, 12 figures
title: Quality assurance in Irish ultrasound departments
Creators: name: Ward, Amy
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Foetal imaging
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Ultrasound-Spectral Doppler
subject: Technical aspects
subject: Outcomes
subject: Image verification
subject: Infection

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The benefits of continuous quality assurance (QA) in diagnostic ultrasound have been widely recognised, QA contributes to equipment efficacy, accuracy of diagnosis and patient safety [1-3]. Ultrasound, unlike other imaging modalities that...
Comprehensive treatments for social cognitive deficits in schizophrenia: A critical review and effect-size analysis of controlled studies
Creators: name: Machado, Sergio
name: Gagen, Emily
name: Kurtz, Matthew M.
name: Rocha, Nuno B.F.
name: Penn, David L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Recent advances in psychosocial treatments for schizophrenia have targeted social cognitive deficits. A critical literature review and effect-size (ES) analysis was conducted to investigate the efficacy of comprehensive programs of social cognitive training in schizophrenia. Results revealed 16 controlled studies consisting of seven models of comprehensive treatment with only three of these treatment models investigated in more than one study. The effects of social cognitive training were reported in 11/15 studies that included facial affect recognition skills (ES = .84) and 10/13 studies that included theory-of-mind (ES = .70) as outcomes. Less than half (4/9) of studies that measured attributional style as an outcome reported effects of treatment, but effect sizes across studies were significant (ESs = .30–.52). Theeffect sizes for symptoms were modest, but, with the exception of positive symptoms, significant (ESs = .32–.40). The majority of trials were randomized (13/16), selected active control conditions (11/16) and included at least 30 participants (12/16). Concerns for this area of research include the absence of blinded outcome raters in more than 50% of trials and low rates of utilization of procedures for maintaining treatment fidelity. These findings provide preliminary support for the broader use of comprehensive social cognitive training procedures as a psychosocial intervention for schizophrenia.
Quantification of Einstein-Podolski-Rosen steering for two-qubit states
Creators: name: Costa, A. C. S.
name: Angelo, R. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In the last few years, several criteria to identify Eistein-Podolski-Rosen steering have been proposed and experimentally implemented. On the operational side, however, the evaluation of the steerability degree of a given state has shown to be a difficult task and only a few results are known. In this work, we propose a measure of steering that is based on the maximal violation of well established steering inequalities. Applying this approach to two-qubit states, we managed to derive simple closed formulas for steering in the two- and three-measurement scenarios. Among the options investigated, a measure has been found that correctly satisfies the entanglement-steering-nonlocality hierarchy and reproduces results reported so far.
description: 5 pages, published version
Inhibitory learning approaches to exposure therapy: A critical review and translation to obsessive-compulsive disorder
Creators: name: Abramowitz, Jonathan S.
name: Jacoby, Ryan J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The majority of treatment research on OCD has focused on pre/post treatment efficacy of exposure-based interventions, with less attention directed towards (a) understanding mechanisms of change, and (b) maximizing long-term effectiveness. Inhibitory learning theory (ILT) provides a novel foundation for understanding how exposure therapy reduces fear. Moreover, ILT is consistent with empirical evidence that raises questions about the more traditional (i.e., habituation) explanation for exposure therapy's efficacy. Yet ILT has yet to be applied to understanding the treatment of OCD and its heterogeneity. The current review is an examination of human experimental research on ILT that seeks to translate laboratory findings on fear extinction to exposure therapy across empirically established OCD symptom dimensions. We provide an up-to-date critical review of the existing evidence for a series of strategies derived from ILT that have been proposed for the treatment of fear, discuss the limitations of existing studies, and provide suggestions for future research within this rapidly accelerating area of study. We also offer conceptual considerations for applying these principles to the treatment of OCD symptom dimensions. A common theme is the idea of introducing "desirable difficulties" into the implementation of exposure in order to foster more durable long-term learning.
Transgressing boundaries: Gender, identity, culture, and 'other' in postcolonial women's narratives in Africa
Creators: name: Oldfield, Elizabeth F.
Publisher: name: University of Derby
Year: 2010
Subjects: Transgressing boundaries
Identity
Other
Feminism
African feminism
Nego-feminism
Postcolonialism
Gender
Culture
Normative femininity

description: Fictions written between 1939 and 2005 by indigenous and white (post)colonial women writers who emerge from an African/European cultural experience form the focus of this study. Their voyages into the European diasporic space in Africa within the context of their texts are important since they speak of how African women's literature develops from, and is situated in relation to colonialism. African literature constitutes one facet of the new literatures in English from formerly colonised countries. However, the accomplishments of indigenous writer Grace Ogot are eclipsed by the critical acclaim received by her male counterparts, whilst Elspeth Huxley, Barbara Kimenye and Marjorie Oludhe Macgoye, who emanate from Western culture but adopt an African perspective, are not accommodated by the `expatriate literature' genre. Hence, indigenous and white (post)colonial women's narratives by authors issuing from an African/European cultural experience are brought together to foreground European influence as an apparent phenomenon common to both categories of writers, with consequences for the representation of gender, identity, culture and the `Other'. The selected texts are set in Kenya and Uganda, and a main concern is with the extent to which the works are impacted upon by setting and intercultural influences. However, this thesis argues that the `African' woman's creation of textuality is at once the formulation and expression of female individualities and a transgression of boundaries. Furthermore, Kimenye and Macgoye's children's literature illustrates the representation and configuration of a voice and identity for the female `Other' and writer, which enables a re-negotiation of identity and subsequently a crossing of borders. No critical study combines indigenous and white settler women's fiction written from an African perspective and therefore this study extends current scholarly knowledge. Whilst the combination of texts together with the disparate (post)colonial backgrounds is unique, the study of Kimenye and Macgoye's African children's narratives in particular breaks new ground since there is currently no critical comparative study pertaining to indigenous and white postcolonial women's children's literature with an African perspective.
Finite-Size Effects in Disordered $λϕ^{4}$ Model
Creators: name: Diaz, R. Acosta
name: Svaiter, N. F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We discuss finite-size effects in one disordered $λϕ^{4}$ model defined in a $d$-dimensional Euclidean space. We consider that the scalar field satisfies periodic boundary conditions in one dimension and it is coupled with a quenched random field. In order to obtain the average value of the free energy of the system we use the replica method. We first discuss finite-size effects in the one-loop approximation in $d=3$ and $d=4$. We show that in both cases there is a critical length where the system develop a second-order phase transition, when the system presents long-range correlations with power-law decay. Next, we improve the above result studying the gap equation for the size- dependent squared mass, using the composite field operator method. We obtain again, that the system present a second order phase transition with long-range correlation with power-law decay.
description: 19 pages, 4 figures
title: Fractures of the temporal bone: an easier way to read your CT
Creators: name: Venkatasamy, Aina
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Head and neck
subject: Ear / Nose / Throat
subject: Trauma
subject: CT
subject: Diagnostic procedure
subject: Trauma

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: With this study, we propose an innovative and simpler approach to traumatic lesions of the temporal bone that differs from the traditional labyrinthine versus extralabyrintine dichotomic approach, associated with a description of the orientation of...
Psychological treatments for adults with posttraumatic stress disorder: A systematic review and meta-analysis
Creators: name: Gaynes, Bradley N.
name: Forneris, Catherine A.
name: Greenblatt, Amy
name: Middleton, Jennifer Cook
name: Jonas, Daniel E.
name: Olmsted, Kristine Rae
name: Cusack, Karen
name: Wines, Candi
name: Brownley, Kimberly A.
name: Sonis, Jeffrey
name: Weil, Amy
name: Feltner, Cynthia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Numerous guidelines have been developed over the past decade regarding treatments for Posttraumatic stress disorder (PTSD). However, given differences in guideline recommendations, some uncertainty exists regarding the selection of effective PTSD therapies. The current manuscript assessed the efficacy, comparative effectiveness, and adverse effects of psychological treatments for adults with PTSD. We searched MEDLINE, Cochrane Library, PILOTS, Embase, CINAHL, PsycINFO, and the Web of Science. Two reviewers independently selected trials. Two reviewers assessed risk of bias and graded strength of evidence (SOE). We included 64 trials; patients generally had severe PTSD. Evidence supports efficacy of exposure therapy (high SOE) including the manualized version Prolonged Exposure (PE); cognitive therapy (CT), cognitive processing therapy (CPT), cognitive behavioral therapy (CBT)-mixed therapies (moderate SOE); eye movement desensitization and reprocessing (EMDR) and narrative exposure therapy (low-moderate SOE). Effect sizes for reducing PTSD symptoms were large (e.g., Cohen's d ~-1.0 or more compared with controls). Numbers needed to treat (NNTs) were <4 to achieve loss of PTSD diagnosis for exposure therapy, CPT, CT, CBT-mixed, and EMDR. Several psychological treatments are effective for adults with PTSD. Head-to-head evidence was insufficient to determine these treatments' comparative effectiveness, and data regarding adverse events was absent from most studies.
Evolution of mid-infrared galaxy luminosity functions from the entire AKARI NEP-Deep field with new CFHT photometry
Creators: name: Goto, Tomotsugu
name: Oi, Nagisa
name: Ohyama, Youichi
name: Malkan, Matthew
name: Matsuhara, Hideo
name: Wada, Takehiko
name: Karouzos, Marios
name: Im, Myungshin
name: Nakagawa, Takao
name: Buat, Veronique
name: Burgarella, Denis
name: Sedgwick, Chris
name: Toba, Yoshiki
name: Jeong, Woong-Seob
name: Marchetti, Lucia
name: Małek, Katarzyna
name: Koptelova, Ekaterina
name: Chao, Dani
name: Wu, Yi-Han
name: Pearson, Chris
name: Takagi, Toshinobu
name: Lee, Hyung Mok
name: Serjeant, Stephen
name: Takeuchi, Tsutomu T.
name: Kim, Seong Jin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present infrared galaxy luminosity functions (LFs) in the AKARI North Ecliptic Pole (NEP) deep field using recently-obtained, wider CFHT optical/near-IR images. AKARI has obtained deep images in the mid-infrared (IR), covering 0.6 deg$^2$ of the NEP deep field. However, our previous work was limited to the central area of 0.25 deg$^2$ due to the lack of optical coverage of the full AKARI NEP survey. To rectify the situation, we recently obtained CFHT optical and near-IR images over the entire AKARI NEP deep field. These new CFHT images are used to derive accurate photometric redshifts, allowing us to fully exploit the whole AKARI NEP deep field. AKARI's deep, continuous filter coverage in the mid-IR wavelengths (2.4, 3.2, 4.1, 7, 9, 11, 15, 18, and 24$μ$m) exists nowhere else, due to filter gaps of other space telescopes. It allows us to estimate restframe 8$μ$m and 12$μ$m luminosities without using a large extrapolation based on spectral energy distribution (SED) fitting, which was the largest uncertainty in previous studies. Total infrared luminosity (TIR) is also obtained more reliably due to the superior filter coverage. The resulting restframe 8$μ$m, 12$μ$m, and TIR LFs at $0.15
description: Accepted for publication in A&A. A related video is at https://youtu.be/ZFYlIPg28E8
Antimicrobial Agent Dosing in Infants
Creators: name: Laughon, Matthew M.
name: Johnson, Jacob K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: AbstractPurposeThe goal of this article was to review infant physiology and its effects on the pharmacokinetic properties of antimicrobial agents.MethodsA review of the drug development process was performed. A literature search was conducted on the pharmacokinetics of various antimicrobial agents in infants.FindingsThe pharmacokinetic properties of antimicrobial agents in infants are most often affected by the renal maturation of premature infants. Hepatic metabolism and volume of distribution play a common role as well.ImplicationsThe dosing and dosing intervals of various medications were reviewed and compared with details of adult dosing. It is vital to continue to gather pharmacokinetic data in infants to ensure adequate safety and dosing of medications.
title: Experience and outcomes in the use of a pipeline embolisation device (PED) for the treatment of intracranial aneurysms: a single-centre study
Creators: name: James, Karl
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: Vascular
subject: Catheter arteriography
subject: Percutaneous
subject: Embolisation
subject: Stents
subject: Embolism / Thrombosis

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To compare outcome data from a single institution for patients with intracranial aneurysms who were treated using a flow diverting stent with previously published outcome data from other...
Cervical Cancer in Women Aged 35 Years and Younger
Creators: name: Pelkofski, Elizabeth
name: Kim, Kenneth H.
name: Gehrig, Paola A.
name: Stine, Jessica
name: Wages, Nolan A.
name: Cantrell, Leigh A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: AbstractPurposeAge has been evaluated as a prognostic factor in cervical cancer in both hospital- and population-based studies. Results regarding the relation of age and cervical cancer prognosis are conflicting. This study pursued a contemporary assessment of the association of extreme young age at the time of a cervical cancer diagnosis on survival.MethodsInstitutional review board approval was obtained, and retrospective data collection at 2 academic institutions was performed. Inclusion criteria involved women ≤35 years diagnosed with cervical cancer between 1990 and 2012. Data included demographic and prognostic information pertinent to survival and progression. Characteristics of very young (≤25 years) and young (>25–35 years) women were compared. Kaplan-Meier estimates, the log-rank test, and Cox proportional hazards modeling were used to assess the association of age, tumor histology, grade, stage, and parametrial involvement with progression-free survival (PFS) and overall survival (OS).FindingsIncident cases (n = 126) of cervical cancer in patients ≤35 years of age were identified of which complete clinical information was available for 114 women. Fifteen percent (17 of 114) were ≤25 years, with the remaining 85% (97 of 114) being 26 to 35 years of age. Race, smoking status, and marital status were comparable between the 2 groups. Squamous histology dominated overall (77 of 114; 68%) with adenocarcinoma contributing ~25% (30 of 114; 26%) of cases. The majority (96 of 114, 84%) had either stage 1A (31 of 114, 27%) or 1B (65 of 114, 57%) disease. A log-rank test revealed no evidence to infer a difference in either PFS or OS among the age groups (P = 0.511 and P = 0.340). In a univariate analysis, grade and stage significantly affected OS (P < 0.0001, P = 0.045), and stage significantly affected PFS (P < 0.0001). In multivariate modeling, presence of parametrial involvement and histologic cancer type significantly affected both PFS (P = 0.002, P = 0.001) and OS (P = 0.001, P = 0.001).ImplicationsTumor histology, parametrial involvement, and stage continue to be strong prognosticators for PFS and OS. Progression and survival outcomes are age independent in women with cervical cancer ≤35 years of age. Further study of a larger young cohort may potentially yield different outcomes.
Reconstruction and identification of tau lepton decays to hadrons and tau neutrino at CMS
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: This paper describes the algorithms used by the CMS experiment to reconstruct and identify tau to hadrons + tau neutrino decays during Run 1 of the LHC. The performance of the algorithms is studied in proton-proton collisions recorded at a centre-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 19.7 inverse femtobarns. The algorithms achieve an identification efficiency of 50-60%, with misidentification rates for quark and gluon jets, electrons, and muons between per mille and per cent levels.
description: Replaced with published version. Added journal reference
title: Role of CT-angiography and digital subtractional angiography in cerebral aneurysm volume estimation
Creators: name: Navichenka, Aliaksandr
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Neuroradiology brain
subject: Interventional vascular
subject: CT-Angiography
subject: Catheter arteriography
subject: Arterial access
subject: Embolisation
subject: Aneurysms

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Aneurysmal disease, especially acute ruptured cerebral aneurysms, poses a great social problem which is characterized by high rate of resulting disability and even mortality. 1%-10% of the population suffer from this pathology, up to 2% of them -...
title: Acute/subacute small ischaemic lesions on DWI in patients with cerebral amyloid angiopathy and cortical superficial siderosis
Creators: name: Gangemi, Emma
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: CNS
subject: Neuroradiology brain
subject: Vascular
subject: MR
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Ischaemia / Infarction
subject: Haemorrhage

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Cerebral amyloid angiopathy (CAA) is defined by amyloid-b deposition in the mediaand adventitia of cortical and leptomeningeal small- tomedium-sized arteries, arterioles and capillaries. Recent studies using DWI have detected clinically...