cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Localizing and extracting filament distributions from microscopy images.
Creators: name: S.  Basu
name: C.  Liu
name: Rohde, Gustavo
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: Detailed quantitative measurements of biological filament networks represent a crucial step in understanding architecture and structure of cells and tissues, which in turn explain important biological events such as wound healing and cancer metastases. Microscopic images of biological specimens marked for different structural proteins constitute an important source for observing and measuring meaningful parameters of biological networks. Unfortunately, current efforts at quantitative estimation of architecture and orientation of biological filament networks from microscopy images are predominantly limited to visual estimation and indirect experimental inference. Here, we describe a new method for localizing and extracting filament distributions from 2D microscopy images of different modalities. The method combines a filter-based detection of pixels likely to contain a filament with a constrained reverse diffusion-based approach for localizing the filaments centrelines. We show with qualitative and quantitative experiments, using both simulated and real data, that the new method can provide more accurate centreline estimates of filament in comparison to other approaches currently available. In addition, we show the algorithm is more robust with respect to variations in the initial filter-based filament detection step often used. We demonstrate the application of the method in extracting quantitative parameters from confocal microscopy images of actin filaments and atomic force microscopy images of DNA fragments.
Dynamic heterogeneity at the experimental glass transition predicted by transferable machine learning
Creators: name: Jung, Gerhard
name: Biroli, Giulio
name: Berthier, Ludovic
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We develop a transferable machine learning model which predicts structural relaxation from amorphous supercooled liquid structures. The trained networks are able to predict dynamic heterogeneity across a broad range of temperatures and time scales with excellent accuracy and transferability. We use the network transferability to predict dynamic heterogeneity down to the experimental glass transition temperature, $T_g$, where structural relaxation cannot be analyzed using molecular dynamics simulations. The results indicate that the strength, the geometry and the characteristic length scale of the dynamic heterogeneity evolve much more slowly near $T_g$ compared to their evolution at higher temperatures. Our results show that machine learning techniques can provide physical insights on the nature of the glass transition that cannot be gained using conventional simulation techniques.
Can the total angular momentum of u-quarks in the nucleon be accessed at HERMES?
Creators: name: Ellinghaus, F.
name: Nowak, W. -D.
name: Vinnikov, A. V.
name: Ye, Z.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the possibility to acquire information on the generalized parton distribution E and, through a model for E, also on the u-quark total angular momentum J_u by studying deeply virtual Compton scattering and hard exclusive rho0 electroproduction on a transversely polarized hydrogen target at HERMES. It is found that a change in J_u from zero to 0.4 corresponds to a 4σ(2σ) difference in the calculated transverse target-spin asymmetry in deeply virtual Compton scattering (rho0 electroproduction), where σis the total experimental uncertainty.
description: 10 pages, 9 figures
A class of infinite number of unbiased estimators using weighted squared distance for two-deck randomized response model
Creators: name: Naatjes, Daryan
name: Sedory, Stephen A.
name: Singh, Sarjinder
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: We develop a collection of unbiased estimators for the proportion of a population bearing a sensitive characteristic using a randomized response technique with two decks of cards for any choice of weights. The efficiency of the estimator depends on the weights, and we demonstrate how to find an optimal choice. The coefficients of skewness and kurtosis are introduced. We support our findings with a simulation study that models a real survey dataset. We suggest that a careful choice of such weights can also lead to all estimates of proportion lying between [0, 1]. In addition, we illustrate the use of the estimators in a recent study that estimates the proportion of students, 18 years and over, who had returned to the campus and tested positive for COVID-19.
On the role of synaptic stochasticity in training low-precision neural networks
Creators: name: Baldassi, Carlo
name: Gerace, Federica
name: Kappen, Hilbert J.
name: Lucibello, Carlo
name: Saglietti, Luca
name: Tartaglione, Enzo
name: Zecchina, Riccardo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Machine Learning (cs.LG)
subject: Neural and Evolutionary Computing (cs.NE)
subject: Machine Learning (stat.ML)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Stochasticity and limited precision of synaptic weights in neural network models are key aspects of both biological and hardware modeling of learning processes. Here we show that a neural network model with stochastic binary weights naturally gives prominence to exponentially rare dense regions of solutions with a number of desirable properties such as robustness and good generalization performance, while typical solutions are isolated and hard to find. Binary solutions of the standard perceptron problem are obtained from a simple gradient descent procedure on a set of real values parametrizing a probability distribution over the binary synapses. Both analytical and numerical results are presented. An algorithmic extension aimed at training discrete deep neural networks is also investigated.
description: 7 pages + 14 pages of supplementary material
Quantile regression based method for characterizing risk-specific behavioral patterns in relation to longitudinal left-censored biomarker data collected from heterogeneous populations
Creators: name: Lee, MinJae
name: Reininger, Belinda M.
name: Gabriel, Kelley Pettee
name: Ranjit, Nalini
name: Strong, Larkin L.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: There are many studies aimed at promoting positive lifestyle behaviors to reduce lifetime risk of cancer and related diseases. However, assessing these modifiable behaviors through statistical modeling is challenging because of the multidimensionality of interrelated measurements that may dramatically differ between at-risk individuals. Taking into account this heterogeneity while considering the multidimensionality of behavior changes is fundamental to tailoring interventions to their needs. Biomarkers that identify high-risk individuals may help validate proximal measures, but the number of validated methods that link biomarkers to multiple behavioral measurements by determining their dynamic relations with disease risks is limited to just a few, since it requires an advanced statistical methodology to address challenges in analyzing biomarker data, including left-censoring due to limits of detection. To address these challenges, we propose a method that constructs a quantile-specific weighted index of multiple behavioral measurements. Under the quantile regression framework, the proposed method renders a multidimensional view of risk-specific behavioral patterns by connecting them with biomarker levels to provide better insights into heterogeneous behavioral profiles among at-risk populations. We evaluate performances of the proposed method through simulations, and illustrate its applications to the Tu Salud ¡Sí Cuenta! data by examining behavior changes among Mexican-American adults.
Left atrial ligation alters intracardiac flow patterns and the biomechanical landscape in the chick embryo.
Creators: name: Kowalski, William J.
name: Teslovich, Nikola C.
name: Prahlad G. Menon
name: Tinney, Joseph P.
name: Keller, Bradley B.
name: Pekkan, Kerem
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: BACKGROUND: Hypoplastic left heart syndrome (HLHS) is a major human congenital heart defect that results in single ventricle physiology and high mortality. Clinical data indicate that intracardiac blood flow patterns during cardiac morphogenesis are a significant etiology. We used the left atrial ligation (LAL) model in the chick embryo to test the hypothesis that LAL immediately alters intracardiac flow streams and the biomechanical environment, preceding morphologic and structural defects observed in HLHS. RESULTS: Using fluorescent dye injections, we found that intracardiac flow patterns from the right common cardinal vein, right vitelline vein, and left vitelline vein were altered immediately following LAL. Furthermore, we quantified a significant ventral shift of the right common cardinal and right vitelline vein flow streams. We developed an in silico model of LAL, which revealed that wall shear stress was reduced at the left atrioventricular canal and left side of the common ventricle. CONCLUSIONS: Our results demonstrate that intracardiac flow patterns change immediately following LAL, supporting the role of hemodynamics in the progression of HLHS. Sites of reduced WSS revealed by computational modeling are commonly affected in HLHS, suggesting that changes in the biomechanical environment may lead to abnormal growth and remodeling of left heart structures.
A Simple Test of the External Shock Model for the Prompt Emission in Gamma-Ray Bursts
Creators: name: Ramirez-Ruiz, Enrico
name: Granot, Jonathan
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It is demonstrated here that if the prompt GRB emission is produced by the simplest version of the external shock model, a specific relation should prevail between the observed duration, isotropic equivalent energy, and photon peak energy. In essence, this relation arises because both the burst duration and the typical energy of the emitted synchrotron photons depend on the same combination of the, usually poorly constrained, external density at the deceleration radius, $n_{dec}$, and initial bulk Lorentz factor, $Γ_0$. This has the fortunate consequence of making the relation independent of both $Γ_0$ and $n_{dec}$. Unless the efficiency of electron acceleration is very low, synchrotron gamma-rays from the external shock would fail to meet the current observational constraints for the vast majority of GRBs, including those with a smooth, single peak temporal profile. This argues either against an external shock origin for the prompt emission in GRBs or for changes in our understanding of the microphysical and radiation processes occurring within the shocked region.
description: 10 pages, 2 figures; submitted to ApJL
Epipogium aphyllum Sw.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Asparagales
Orchidaceae
Epipogium
Epipogium aphyllum

description: Satyrium epipogium Linnaeus, Species Plantarum 2: 945. 1753.
"Habitat in Sibiriae montibus arenosis." RCN: 6837.
 Lectotype (Renz & Taubenheim in Davis, Fl. Turkey 8: 470. 1984): [icon] “Epipogum” in Gmelin, Fl. Sibirica 1: 12, t. 2, f. 2. 1747.
 Current name:  Epipogium aphyllum  Sw. (Orchidaceae).
 Note: Baumann & al. (in Mitteilungsbl. Arbeitskr. Heim. Orchid. Baden-Württemberg 21: 597, Abb. 16. 1989) reproduce the type plate.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part S), pp. 806-877 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 819, DOI: 10.5281/zenodo.291971
Memorandum Regarding Conversation with Ambassador Micunovic
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1966
Subjects: Box 232 Folder 6
Box 232 Folder 06
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Memorandum of conversation concerning exchanges between Ambassador Micunovic and Llewellyn Thompson concerning Vietam.
Low-energy photon-photon collisions to two loops revisited
Creators: name: Gasser, Juerg
name: Ivanov, Mikhail A.
name: Sainio, Mikko E.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In view of ongoing experimental activities to determine the pion polarizabilities, we have started to recalculate the available two-loop expressions in the framework of chiral perturbation theory, because they have never been checked before. We make use of the chiral Lagrangian at order p^6 now available, and of improved techniques to evaluate the two-loop diagrams. Here, we present the result for the neutral pions. The cross section for the reaction gamma+gamma->pi0+pi0 agrees with the earlier calculation within a fraction of a percent. We present analytic results for the dipole and quadrupole polarizabilities, and compare the latter with a recent evaluation from data on gamma+gamma->pi0+pi0.
description: 28 pages, 7-eps figures, 1 table
A Heroic Pilot Remembered
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: My father, Alan Ernest Budds, was ground crew in Bomber Command in the RAF 75 New Zealand Squadron.My story is about Sergeant Pilot James Allen Ward, who was in the squadron with my father. He won the Victoria Cross for walking along the wing of a plane (a Wellington bomber) to put out a fire.Two months after this Sergeant Pilot Ward was killed in a raid over Hamburg. He is buried there. I have a book written by Alan Mitchell which has a whole chapter on Ward and his heroic war. The book is called "New Zealanders in the Air War".
Memorandum Regarding Interactions and Conversations
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1965
Subjects: Box 232 Folder 6
Box 232 Folder 06
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Memorandum summarzing visit to Arena Theater, conversations with Yugoslav Press Attache Cvijeto and Job, and Tito references.
Himantoglossum hircinum Spreng.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Asparagales
Orchidaceae
Himantoglossum
Himantoglossum hircinum

description: Satyrium hircinum Linnaeus, Species Plantarum 2: 944. 1753.
"Habitat in Galliae, Cantii campestris." RCN: 6833.
 Lectotype (Baumann & al. in Mitteilungsbl. Arbeitskr. Heim. Orchid. Baden-Württemberg 21: 491, Abb. 22. 1989): [icon] " Orchis barbata foetida" in Vaillant, Bot. Paris.: 149, t. 30, f. 6. 1727.
 Current name:  Himantoglossum hircinum  (L.) Spreng. (Orchidaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part S), pp. 806-877 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 819, DOI: 10.5281/zenodo.291971
Measuring Psychosocial Risk Factors at Work: A Systematic Review of Assessment Instruments
Creators: name: Junior, João
Publisher: name: Open Science Framework
Year: 2022

description: To guide researchers, employers, and employees in their choice of the adequate assessment tool to their psychosocial work environment, this study proposes a systematic review and qualitative synthesis of the psychosocial risk factors measurement tools available in different contexts, describing their characteristics and reporting their reliability and validity.
The DEEP2 Galaxy Redshift Survey: AEGIS Observations of a Dual AGN at z=0.7
Creators: name: Gerke, Brian F.
name: Newman, Jeffrey A.
name: Lotz, Jennifer
name: Yan, Renbin
name: Barmby, P.
name: Coil, Alison L.
name: Conselice, Christopher J.
name: Ivison, R. J.
name: Lin, Lihwai
name: Koo, David C.
name: Nandra, Kirpal
name: Salim, Samir
name: Small, Todd
name: Weiner, Benjamin J.
name: Cooper, Michael C.
name: Davis, Marc
name: Faber, S. M.
name: Guhathakurta, Puragra
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present evidence for a dual Active Galactic Nucleus (AGN) within an early-type galaxy at z=0.709 in the Extended Groth Strip. The galaxy lies on the red sequence, with absolute magnitude M_B=-21.0 (AB, with h=0.7) and rest-frame color U-B=1.38. Its optical spectrum shows strong, double-peaked [OIII] emission lines and weak Hbeta emission, with Seyfert-like line ratios. The two narrow peaks are separated by 630 km/s in velocity and arise from two distinct regions, spatially resolved in the DEIMOS spectrum, with a projected physical separation of 1.2 kpc. HST/ACS imaging shows an early-type (E/S0) galaxy with hints of disturbed structure, consistent with the remnant of a dissipationless merger. Multiwavelength photometric information from the AEGIS consortium confirms the identification of a dust-obscured AGN in an early-type galaxy, with detections in X-ray, optical, infrared and radio wavebands. These data are most readily explained as a single galaxy harboring two AGN--the first such system to be observed in an otherwise typical early-type galaxy.
description: 5 pages, 4 figures. Updated to match published version
In-vitro Evaluation of Ventricular Cannulation for Rotodynamic Cardiac Assist Devices.
Creators: name: Bachman, Timothy N.
name: Bhama, Jay K.
name: Verkaik, Josiah
name: Vandenberghe, Stijn
name: Kormos, Robert L.
name: Antaki, James
Publisher: name: Carnegie Mellon University
Year: 2011
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: The influence of positioning and geometry of ventricular cannulas for contemporary continuous flow Left Ventricular Assist Devices (LVADs) was evaluated in a non-beating isolated heart preparation with borescopic visualization. Preload and LVAD flow were varied to evaluate degrees of ventricular decompression up to the point of ventricular collapse. The performance of a flanged cannula was compared to a conventional bevel-tipped cannula: quantitatively by the maximal flow attainable, and qualitatively by visualization of fluid tracer particles within the ventricular chamber. Three forms of ventricular suck-down occurred: concentric collapse, gradual entrainment and instantaneous entrainment. In some circumstances, unstable oscillations of the ventricle were observed prior to complete collapse. Under conditions of low preload, the flanged cannula demonstrated less positional sensitivity, provided greater flow, and exhibited fewer areas of stagnation than the beveled cannula. These observations warrant further consideration of a flanged ventricular cannula to mitigate complications encountered with conventional cannulae.
Regular rapidly decreasing nonlinear generalized functions. Application to microlocal regularity
Creators: name: Delcroix, Antoine
Publisher: name: arXiv
Year: 2006
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 35A18, 35A27, 42B10, 46E10, 46F30

description: We present new types of regularity for nonlinear generalized functions, based on the notion of regular growth with respect to the regularizing parameter of Colombeau's simplified model. This generalizes the notion of G^{\infty }-regularity introduced by M. Oberguggenberger. A key point is that these regularities can be characterized, for compactly supported generalized functions, by a property of their Fourier transform. This opens the door to microanalysis of singularities of generalized functions, with respect to these regularities. We present a complete study of this topic, including properties of the Fourier transform (exchange and regularity theorems) and relationship with classical theory, via suitable results of embeddings.
description: Submitted to the Journal of Mathematical Analysis and Applications
The effect of environment knowledge in evacuation scenarios involving fire and smoke - a multiscale modelling and simulation approach
Creators: name: Richardson, Omar
name: Jalba, Andrei
name: Muntean, Adrian
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Numerical Analysis (math.NA)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 655Z05, 82C70, 91E30

description: We study the evacuation dynamics of a crowd evacuating from a complex geometry in the presence of a fire as well as of a slowly spreading smoke curtain. The crowd is composed of two kinds of individuals: those who know the layout of the building, and those who do not and rely exclusively on potentially informed neighbors to identify a path towards the exit. We aim to capture the effect the knowledge of the environment has on the interaction between evacuees and their residence time in the presence of fire and evolving smoke. Our approach is genuinely multiscale - we employ a two-scale model that is able to distinguish between compressible and incompressible pedestrian flow regimes and allows for micro and macro pedestrian dynamics. Simulations illustrate the expected qualitative behavior of the model. We finish with observations on how mixing evacuees with different levels of knowledge impacts important evacuation aspects.
Universality of the angled shear wave identity in soft viscous solids
Creators: name: Berjamin, Harold
name: Gower, Artur L.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences
subject: 74J05 (Primary) 74D10 (Secondary)

description: Mechanical stress within biological tissue can indicate an anomaly, or can be vital of its function, such as stresses in arteries. Measuring these stresses in tissue is challenging due to the complex, and often unknown, nature of the material properties. Recently, a method called the angled shear wave identity was proposed to predict the stress by measuring the speed of two small amplitude shear waves. The method does not require prior knowledge of the material's constitutive law, making it ideal for complex biological tissues. We extend this method, and the underlying identity, to include viscous dissipation, which can be significant for biological tissues. To generalise the identity, we consider soft viscoelastic solids described by a generalised Newtonian viscous stress, and account for transverse isotropy, a feature that is common in muscle tissue, for instance. We then derive the dispersion relationship for small-amplitude shear waves superimposed on a large static deformation. Similarly to the elastic case, the identity is recovered when the stress in the material is coaxial with the transverse anisotropy. A key result in this paper is that to predict the stress in a viscous material one would need to measure the wave attenuation as well as the wave speed. The case of viscoelastic materials with memory is also discussed.
Note Regarding Deputy Prime Minister Visit
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1968
Subjects: Box 232 Folder 7
Box 232 Folder 07
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Note from Davis to Rostow detailing logistics of meeting with Gligorov.
Investigating developmental cardiovascular biomechanics and the origins of congenital heart defects.
Creators: name: Kowalski, William J.
name: Pekkan, Kerem
name: Tinney, Joseph P.
name: Keller, Bradley
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: Innovative research on the interactions between biomechanical load and cardiovascular (CV) morphogenesis by multiple investigators over the past 3 decades, including the application of bioengineering approaches, has shown that the embryonic heart adapts both structure and function in order to maintain cardiac output to the rapidly growing embryo. Acute adaptive hemodynamic mechanisms in the embryo include the redistribution of blood flow within the heart, dynamic adjustments in heart rate and developed pressure, and beat to beat variations in blood flow and vascular resistance. These biomechanically relevant events occur coincident with adaptive changes in gene expression and trigger adaptive mechanisms that include alterations in myocardial cell growth and death, regional and global changes in myocardial architecture, and alterations in central vascular morphogenesis and remodeling. These adaptive mechanisms allow the embryo to survive these biomechanical stresses (environmental, maternal) and to compensate for developmental errors (genetic). Recent work from numerous laboratories shows that a subset of these adaptive mechanisms is present in every developing multicellular organism with a "heart" equivalent structure. This chapter will provide the reader with an overview of some of the approaches used to quantify embryonic CV functional maturation and performance, provide several illustrations of experimental interventions that explore the role of biomechanics in the regulation of CV morphogenesis including the role of computational modeling, and identify several critical areas for future investigation as available experimental models and methods expand.
Intracellular recordings of action potentials by an extracellular nanoscale field-effect transistor.
Creators: name: Xiaojie  Duan
name: Ruixuan  Gao
name: Xie, Ping
name: Itzhaq Cohen-Karni
name: Qing, Quan
name: Choe, Hwan Sung
name: Bozhi  Tian
name: Xiaocheng  Jiang
name: Lieber, Charles M.
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: The ability to make electrical measurements inside cells has led to many important advances in electrophysiology. The patch clamp technique, in which a glass micropipette filled with electrolyte is inserted into a cell, offers both high signal-to-noise ratio and temporal resolution. Ideally, the micropipette should be as small as possible to increase the spatial resolution and reduce the invasiveness of the measurement, but the overall performance of the technique depends on the impedance of the interface between the micropipette and the cell interior, which limits how small the micropipette can be. Techniques that involve inserting metal or carbon microelectrodes into cells are subject to similar constraints. Field-effect transistors (FETs) can also record electric potentials inside cells, and because their performance does not depend on impedance, they can be made much smaller than micropipettes and microelectrodes. Moreover, FET arrays are better suited for multiplexed measurements. Previously, we have demonstrated FET-based intracellular recording with kinked nanowire structures, but the kink configuration and device design places limits on the probe size and the potential for multiplexing. Here, we report a new approach in which a SiO2 nanotube is synthetically integrated on top of a nanoscale FET. This nanotube penetrates the cell membrane, bringing the cell cytosol into contact with the FET, which is then able to record the intracellular transmembrane potential. Simulations show that the bandwidth of this branched intracellular nanotube FET (BIT-FET) is high enough for it to record fast action potentials even when the nanotube diameter is decreased to 3 nm, a length scale well below that accessible with other methods. Studies of cardiomyocyte cells demonstrate that when phospholipid-modified BIT-FETs are brought close to cells, the nanotubes can spontaneously penetrate the cell membrane to allow the full-amplitude intracellular action potential to be recorded, thus showing that a stable and tight seal forms between the nanotube and cell membrane. We also show that multiple BIT-FETs can record multiplexed intracellular signals from both single cells and networks of cells.
MPEC 2024-U163 : 2024 UA5
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 UA5

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Manipulating composition gradient in cuprate superconducting thin films
Creators: name: Yu, Heshan
name: Yuan, Jie
name: Zhu, Beiyi
name: Jin, Kui
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The techniques of growing films with different parameters in single process make it possible to build up a sample library promptly. In this work, with a precisely controlled moving mask, we synthetized superconducting La2-xCexCuO4+/-δ combinatorial films on one SrTiO3 substrate with the doping levels from x = 0.1 to 0.19. The monotonicity in doping along the designed direction is verified by micro-region x-ray diffraction and electric transport measurements. More importantly, by means of numerical simulation, the real change of doping levels is in accordance with a linear gradient variation of doping levels in the La2-xCexCuO4+/-δ combinatorial films. Our results indicate that it is promising to accurately investigate materials with critical composition by combinatorial film technique.
description: 4 pages, 4 figures, cover story
Pseudoscalar Decay Constants $ f_{D} $ and $ f_{D_s} $ in Lattice QCD with Exact Chiral Symmetry
Creators: name: Chiu, Ting-Wai
name: Hsieh, Tung-Han
name: Lee, Jon-Yu
name: Liu, Pei-Hua
name: Chang, Hsiu-Ju
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We determine the masses and decay constants of pseudoscalar mesons $ D $, $ D_s $, and $ K $ in quenched lattice QCD with exact chiral symmetry. For 100 gauge configurations generated with single-plaquette action at $ β= 6.1 $ on the $ 20^3 \times 40 $ lattice, we compute point-to-point quark propagators for 30 quark masses in the range $ 0.03 \le m_q a \le 0.80 $, and measure the time-correlation functions of pseudoscalar and vector mesons. The inverse lattice spacing $ a^{-1} $ is determined with the experimental input of $ f_π$, while the strange quark bare mass $ m_s a = 0.08 $, and the charm quark bare mass $ m_c a = 0.80 $ are fixed such that the masses of the corresponding vector mesons are in good agreement with $ ϕ(1020) $ and $ J/ψ(3097) $ respectively. Our results of pseudoscalar-meson decay constants are $ f_K = 152(6)(10) $ MeV, $ f_D = 235(8)(14)$ MeV, and $ f_{D_s} = 266(10)(18) $ MeV.
description: 14 pages, 6 eps figures
Erythrodes hirtella Fawc. & Rendle
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Asparagales
Orchidaceae
Erythrodes
Erythrodes hirtella

description: Satyrium latifolium Linnaeus, Flora Jamaicensis: 20. 1759.
"Habitat [in Jamaica.]"
 Lectotype (Garay & Sweet in Howard, Fl. Lesser Antilles, Orchidaceae: 83. 1974): Herb. Linn. No. 1055.6 (LINN).
 Current name:  Erythrodes hirtella  (Sw.) Fawc. & Rendle (Orchidaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part S), pp. 806-877 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 819, DOI: 10.5281/zenodo.291971
Game-theoretic versions of strong law of large numbers for unbounded variables
Creators: name: Kumon, Masayuki
name: Takemura, Akimichi
name: Takeuchi, Kei
Publisher: name: arXiv
Year: 2006
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60F15

description: We consider strong law of large numbers (SLLN) in the framework of game-theoretic probability of Shafer and Vovk (2001). We prove several versions of SLLN for the case that Reality's moves are unbounded. Our game-theoretic versions of SLLN largely correspond to standard measure-theoretic results. However game-theoretic proofs are different from measure-theoretic ones in the explicit consideration of various hedges. In measure-theoretic proofs existence of moments are assumed, whereas in our game-theoretic proofs we assume availability of various hedges to Skeptic for finite prices.
Telegram Regarding Tito and Harriman Meeting
Creators: name: United States. Embassy (Belgrade)
Publisher: name: The University of Texas at Austin
Year: 1967
Subjects: Box 232 Folder 9
Box 232 Folder 09
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Telegram concerning logistics of meeting between Tito and Governor Harriman.
Cost-effectiveness of cladribine tablets, alemtuzumab, and natalizumab in the treatment of relapsing-remitting multiple sclerosis with high disease activity in England
Creators: name: Hettle, Robert
name: Harty, Gerard
name: Schiffon L. Wong
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Aims: Cladribine tablets were the first oral short-course treatment approved for highly active relapsing multiple sclerosis (MS). The Association of British Neurologists guidelines currently recommend two infusion therapies, alemtuzumab and natalizumab, to treat high disease activity relapsing remitting MS (HDA-RRMS). This analysis assessed the cost-effectiveness of cladribine tablets in HDA-RRMS compared with alemtuzumab and natalizumab, from the perspective of the National Health Service (NHS) in England. Materials and methods: A cohort-based Markov model with 11 health states (10 Expanded Disability Status Scale [EDSS] plus death) was developed. Transition matrices from the British Columbia registry were used to model the natural history of EDSS. The treatment effect on EDSS was modelled using hazard ratios for 6-month confirmed disability progression from an indirect treatment comparison (ITC). Relapses and drug-related adverse events were modeled via annualized relapse rates and event probabilities, with associated costs and quality-adjusted life year (QALY) losses. Utilities were derived from trials and the literature, and costs from NHS and literature sources. Uncertainty was assessed via probabilistic and deterministic sensitivity analyses. Results: Cladribine tablets were dominant (i.e., less costly and more effective) vs alemtuzumab and natalizumab in pairwise comparisons, and the dominant strategy in fully incremental analyses. Incremental cost was driven largely by drug acquisition and administration costs, and incremental QALY gain largely by differences in delayed EDSS progression. Cladribine tablets had a 93% probability of being cost-effective at a threshold of GBP 30,000 per QALY gained, and remained dominant across the scenario analyses tested. The greatest influence on results was the treatment effect on disability progression derived from the ITC. Limitations: Uncertainty over the efficacy of DMT beyond trial durations. In line with other comparative effectiveness analyses, the network meta-analysis informing this cost-effectiveness analysis was associated with a degree of uncertainty. No treatment switching analyses were undertaken. Conclusions: Cladribine tablets are a cost-effective alternative to alemtuzumab and natalizumab in the treatment of HDA-RRMS from the perspective of the NHS in England.
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00203
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: cartulaire
subject: Chartes de la Bourgogne du Moyen Âge

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00203, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00203, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
AEGIS: Host Galaxy Morphologies of X-ray and Infrared-selected AGN at 0.2 < z < 1.2
Creators: name: Pierce, C. M.
name: Lotz, J. M.
name: Laird, E. S.
name: Lin, L.
name: Nandra, K.
name: Primack, J. R.
name: Faber, S. M.
name: Barmby, P.
name: Park, S. Q.
name: Willner, S. P.
name: Gwyn, S.
name: Koo, D. C.
name: Coil, A. L.
name: Cooper, M. C.
name: Georgakakis, A.
name: Koekemoer, A. M.
name: Noeske, K. G.
name: Weiner, B. J.
name: Willmer, C. N. A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We visually and quantitatively determine the host galaxy morphologies of 94 intermediate redshift (0.2 < z < 1.2) active galactic nuclei (AGN), selected using Chandra X-ray and Spitzer mid-infrared data in the Extended Groth Strip. Using recently developed morphology measures, the second-order moment of the brightest 20% of a galaxy's flux (M_{20}) and the Gini coefficient, we find that X-ray-selected AGN mostly reside in E/S0/Sa galaxies (53^{+11}_{-10}%), while IR-selected AGN show no clear preference for host morphology. X-ray-selected AGN hosts are members of close pairs more often than the field population by a factor of 3.3+/-1.4, but most of these pair members appear to be undisturbed early-type galaxies and do not tend to show direct evidence of gravitational perturbations or interactions. Thus, the activation mechanism for AGN activity remains unknown, even for pair members.
description: 11 pages, 2 figures, 1 table, accepted for publication in ApJL
Memorandum Regarding Comments on Mr. Brzezinski's Memorandum
Creators: name: United States. White House
Publisher: name: The University of Texas at Austin
Year: 1967
Subjects: Box 232 Folder 13
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Memorandum from Davis to Rostow concerning suggestions from Zbigniew Brzinski on briefing Congressional leaders, a study, and confidential NATO discussions.
Memories of Clapham Bombing - Jack Stevens' War Memoirs
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Jean brought her brother Jack's memoirs of his war service, written in 1991 to the Collection Day. He was 13 years older than she.A photo taken in 1946 shows the wedding of her sister to Londoner, Harry Colbourn. Jean remembers that everyone donated clothing coupons for her sister's wedding. Jean, aged 12, hated her new shoes and ran out of the shop crying when they were purchased.In the photograph, Jean is the girl on the far right, and Jack is the fourth from the left.Jean's father worked in a torpedo factory. He had served in WW1. He was the lead driver of a gun carriage. He loved his horses and travelled by ship with them.Jean remembers an occasion when she and her siblings were swooped on by a Messerschmidt. Her 15-year-old sister threw them into the bushes. "It turned my brother's brain for some time - he was nine and a half, I was seven."I actually remember when I was walking to school with my mum and another little friend and Mum said, "We are at war".My father had a van in which he always kept a section of piping. This would have been attached to the exhaust and the family gassed if we were invaded. His mother was Jewish, so he knew what would happen. We lived in Weymouth, near the seafront. Later Dad found a job in Horsham, where there were no raids, but then he had to do war work and we moved to Clapham. My sister too was involved in war work - she did welding and cycled to Richmond each day. Later she was a Land Army girl working on a farm on Vicarage Hill on Essex Way (Benfleet) opposite where she lived.Jean's father made a shelter for the family under their home in Clapham, which was quite comfortable. "When the bombing was really bad we used to go to the basement at Decca Records nearby and take our bedding." On Saturdays, the family would clean the house and rotate the jobs among themselves."I went to get the fish and chips for lunch and the sirens went - they were trying to knock out Clapham Junction. In the fish shop, we all crouched down behind a wall. We heard a doodlebug, then silence. A house caught a lot of the blast. There was thick black smoke. A policeman stopped me and asked why I was crying. Then my mother came out, wearing her turban, her face covered in blood and crying, "My baby!" Luckily my family were under the stairs. The glass front door had splintered into the wall behind it. It looked really pretty. We had to go to a centre and sleep in bunks. My sister was looking after us. My aunt in Benfleet had a second house and offered it to us. It was like paradise, it was lovely and we were safe! On V.E. day there were lots of celebrations. At midnight we walked all the way from Southend to Hadleigh, everybody was celebrating, linking arms, walking and singing.
Invariants de classes : exemples de non-annulation en dimension supérieure
Creators: name: Gillibert, Jean
Publisher: name: arXiv
Year: 2006
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14Kxx; 11Gxx

description: The so-called class-invariant homomorphism $ψ$ measures the Galois module structure of torsors--under a finite flat group scheme $G$--which lie in the image of a coboundary map associated to an isogeny between (Néron models of) abelian varieties with kernel $G$. When the varieties are elliptic curves with semi-stable reduction and the order of $G$ is coprime to 6, is is known that the homomorphism $ψ$ vanishes on torsion points. In this paper, using Weil restrictions of elliptic curves, we give the construction, for any prime number $p>2$, of an abelian variety $A$ of dimension $p$ endowed with an isogeny (with kernel $μ_p$) whose coboundary map is surjective. In the case when $A$ has rank zero and the $p$-part of the Picard group of the base is non-trivial, we obtain examples where $ψ$ does not vanishes on torsion points.
description: 20 pages, LaTeX. Small changes
Memorandum Regarding Farewell Call
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1967
Subjects: Box 232 Folder 13
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Memorandum from Read to Rostow concerning leave of Ambassador Micunovic and diplomatic signalling towards Yugoslavia.
On Micropolar Elastic Foundations
Creators: name: Athanasiadis, Adrianos E. F.
name: Budzik, Michal K.
name: Fernando, Dilum
name: Dias, Marcelo A.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: The modelling of heterogeneous and architected materials poses a significant challenge, demanding advanced homogenisation techniques. However, the complexity of this task can be considerably simplified through the application of micropolar elasticity. Conversely, elastic foundation theory is widely employed in fracture mechanics and the analysis of delamination propagation in composite materials. This study aims to amalgamate these two frameworks, enhancing the elastic foundation theory to accommodate materials exhibiting micropolar behaviour. Specifically, we present a novel theory of elastic foundation for micropolar materials, employing stress potentials formulation and a unique normalisation approach. Closed-form solutions are derived for stress and couple stress reactions inherent in such materials, along with the associated restoring stiffness. The validity of the proposed theory is established through verification using the double cantilever beam configuration. Concluding our study, we elucidate the benefits and limitations of the developed theory by quantifying the derived parameters for materials known to exhibit micropolar behaviour. This integration of micropolar elasticity into the elastic foundation theory not only enhances our understanding of material responses but also provides a versatile framework for the analysis of heterogeneous materials in various engineering applications.