cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The volatility spillovers of U.S. quantitative easing: evidence from Australia
Creators: name: Yahyaei, Hamid
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This dissertation investigates the cross-market volatility spillovers induced by U.S. Quantitative Easing (QE) programs. Specifically, this study examines the volatility that commences in U.S. financial markets and spreads to Australian equity and government bond markets. The study features the creation of animplied volatility index for the Australian government bond market that is considered alongside other implied volatility indices to create dynamic measures of cross-market spillovers. Data-driven Structural Vector Autoregressive (SVAR) models are then estimated to assess the impact of an unexpected QE shock on volatility transmission. The study finds evidence of an intensification of volatility spillovers that is explained by QE, primarily during the period of policy normalisation. The QE-induced volatility transmission between the U.S. and Australian equity markets is found to be especially pronounced. Furthermore, the results show that contractionary QE shocks promote an increase in volatility spillovers, while expansionary shocks suppress them. This study is among the first to provide a comprehensive analysis of the cross-border effects of U.S. QE programs on Australian financial markets, contributing to a growing set of literature that examines the implications of unconventional monetary policies -- abstract.
MOESM2 of Methods for detecting Gemmata spp. bacteremia in the microbiology laboratory
Creators: name: Jacques-Robert Christen
name: Edmond, Edwin
name: Drancourt, Michel
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 2: Table S1. qPCR performed on samples extracted from EDTA and heparin tubes.
Effect of alignment on polarized infrared emission from polycyclic aromatic hydrocarbons
Creators: name: Hoang, Thiem
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Polarized emission from polycyclic aromatic hydrocarbons (PAHs) potentially provides a new way to test basic physics of the alignment of ultrasmall grains. In this paper, we present a new model of polarized PAH emission that takes into account the effect of PAH alignment with the magnetic field. We first generate a large sample of the grain angular momentum $\bf J$ by simulating the alignment of PAHs due to resonance paramagnetic relaxation that accounts for various interaction processes. We then calculate the polarization level of PAH emission features, for the different phases of the ISM, including the cold neutral medium (CNM), reflection nebulae (RN), and photodissociation regions (PDRs). We find that a moderate degree of PAH alignment can significantly enhance the polarization degree of PAH emission compared to the previous results obtained with randomly oriented $\bf J$. In particular, we find that smallest, negatively charged PAHs in RN can be excited to slightly suprathermal rotation due to enhanced ion collisional excitation, resulting in an increase of the polarization with the ionization fraction. Our results suggest that RN is the most favorable environment to observe polarized PAH emission and to test alignment physics of nanoparticles. Finally, we present an explicit relationship between the polarization level of PAH emission and the degree of external alignment for the CNM and RN. The obtained relationship will be particularly useful for testing alignment physics of PAHs by future observations.
description: 15 figures, 20 pages
Raising children matters: an exploration of family online social media networking experiences
Creators: name: Stipanovic, Suzana
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Australian families raising children today are turning to the internet for parenting information and support. As the wellbeing of children and families is connected with the support families receive (Grace, Hayes, & Wise, 2017), research into online support being accessed by families with children is warranted. Content analysis of postings on the online forums within the Raising Children Network over a six-month period was conducted to ascertain insights about respondents' interests regarding raising children in Australia today. To gain further insights into how participation in social networking sites may influence family experiences, parents utilising social media were also invited to complete an online survey. Online behaviours such as passive support and cyber lurking were found within the online forum postings analysed, and were also reported by the survey respondents. These findings can inform those managing online parenting networks about aspects that require better monitoring and moderation of participation in social media forums aimed at supporting those raising children today. These findings can also be used by educators to advise and assist families in early childhood settings to adopt a variety of strategies for online interactions, optimise the potential social supports available through social media, and enhance knowledge sharing within cyber communities.
Feasibility Studies for Single Transverse-Spin Asymmetry Measurements at a Fixed-Target Experiment Using the LHC Proton and Lead Beams (AFTER@LHC)
Creators: name: Kikoła, Daniel
name: Echevarria, Miguel García
name: Hadjidakis, Cynthia
name: Lansberg, Jean-Philippe
name: Lorcé, Cedric
name: Massacrier, Laure
name: Quintans, Catarina Marques
name: Signori, Andrea
name: Trzeciak, Barbara
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The measurement of Single Transverse-Spin Asymmetries, $A_N$, for various quarkonium states and Drell-Yan lepton pairs can shed light on the orbital angular momentum of quarks and gluons, a fundamental ingredient of the proton-spin puzzle. The AFTER@LHC proposal combines a unique kinematic coverage and large luminosities thanks to the Large Hadron Collider beams to deliver precise measurements, complementary to the knowledge provided by collider experiments such as at RHIC. In this paper, we report on sensitivity studies for $J/ψ$, $Υ$ and Drell-Yan $A_N$ done using the performance of LHCb-like or ALICE-like detectors, combined with polarised gaseous hydrogen and helium-3 targets. In particular, such analyses will provide us with new insights and knowledge about transverse-momentum-dependent parton distribution functions for quarks and gluons and on twist-3 collinear matrix elements in the proton and the neutron.
description: 16 pages, 8 figures
Additional file 1: of Effect of eicosapentaenoic acid/docosahexaenoic acid on coronary high-intensity plaques detected with non-contrast T1-weighted imaging (the AQUAMARINE EPA/DHA study): study protocol for a randomized controlled trial
Creators: name: Nakao, Kazuhiro
name: Noguchi, Teruo
name: Asaumi, Yasuhide
name: Morita, Yoshiaki
name: Kanaya, Tomoaki
name: Fujino, Masashi
name: Hosoda, Hayato
name: Yoneda, Shuichi
name: Kawakami, Shoji
name: Nagai, Toshiyuki
name: Nishihira, Kensaku
name: Nakashima, Takahiro
name: Reon Kumasaka
name: Arakawa, Tetsuo
name: Fumiyuki Otsuka
name: Nakanishi, Michio
name: Kataoka, Yu
name: Tahara, Yoshio
name: Goto, Yoichi
name: Yamamoto, Haruko
name: Hamasaki, Toshimitsu
name: Yasuda, Satoshi
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: SPIRIT 2013 Checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 119Â kb)
Chained Bell Inequality Experiment with High-Efficiency Measurements
Creators: name: Tan, T. R.
name: Wan, Y.
name: Erickson, S.
name: Bierhorst, P.
name: Kienzler, D.
name: Glancy, S.
name: Knill, E.
name: Leibfried, D.
name: Wineland, D. J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We report correlation measurements on two $^9$Be$^+$ ions that violate a chained Bell inequality obeyed by any local-realistic theory. The correlations can be modeled as derived from a mixture of a local-realistic probabilistic distribution and a distribution that violates the inequality. A statistical framework is formulated to quantify the local-realistic fraction allowable in the observed distribution without the fair-sampling or independent-and-identical-distributions assumptions. We exclude models of our experiment whose local-realistic fraction is above 0.327 at the 95 \% confidence level. This bound is significantly lower than 0.586, the minimum fraction derived from a perfect Clauser-Horne-Shimony-Holt inequality experiment. Furthermore, our data provides a device-independent certification of the deterministically created Bell states.
Lettre de Etienne et Edmé Piestre et Cormon à Jean-François Séguier, 1781-06-22
Creators: name: Piestre et Cormon, Etienne et Edmé
name: Cormon, Etienne Et Edmé Piestre Et
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Librairie

description: [transcription] Nîmes M. Séguier A Lyon, le 22 juin 1781.

Monsieur,

Nous avons eu l'honneur de vous écrire le 31e passé en vous avisant la remise à Messieurs Devillas et Cie d'un petit paquet pour vous, montant à 4 lt. et 2 lt. pour le montant du précédent petit paquet, ce qui fait 6 lt. et 4 lt. pour nos frais au petit paquet, que nous avons reçu ces jours derniers l'envoi de M. de Servières pour vous faire passer, ce qui fait 10 lt. que vous nous devez à présent. Nous avons remis ce paquet avant-hier à Messieurs de Villas qui le vont mettre dans le 1er envoi qu'ils vont faire à la maison de votre ville et qu'il vous plaira faire retirer. Voilà qui s'offre à vous faire part aujourd'hui, en attendant ce moment et un ordre de votre part, nous avons l'honneur d'être avec une considération respectueuse distinguée,

Monsieur,

Vos très humbles et très obéissants serviteurs

Piestre et Cormon
description: [personnes citées] Claude-Urbain de Retz de Bressolles, baron de Servières, Messieurs (Négociants à Lyon et à Nîmes) Devillas
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 312_1, fol. 136
description: Source: ark:/12148/btv1b10015922t
When does the Weyl-von Neumann Theorem hold?
Creators: name: Ando, Hiroshi
name: Matsuzawa, Yasumichi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Spectral Theory (math.SP)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 47B25

description: A famous theorem due to Weyl and von Neumann asserts that two bounded self-adjoint operators are unitarily equivalent modulo the compacts, if and only if their essential spectrum agree. The above theorem does not hold for unbounded operators. Nevertheless, there exist closed subsets $M$ of $\mathbb{R}$ on which the Weyl--von Neumann Theorem hold: all (not necessarily bounded) self-adjoint operators with essential spectrum $M$ are unitarily equivalent modulo the compacts. In this paper, we determine exactly which $M$ satisfies this property.
description: 3 pages
Formation of Cu6Sn5 phase by cold homogenization in nanocrystalline Cu-Sn bilayers at room temperature
Creators: name: Zaka, H.
name: Shenouda, S. S.
name: Fouad, S. S.
name: Medhat, M.
name: Katona, G. L.
name: Csik, A.
name: Langer, G. A.
name: Beke, D. L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Solid state reaction between nanocrystalline Cu and Sn films was investigated at room temperature by depth profiling with secondary neutral mass spectrometry and by X-ray diffraction. A rapid diffusion intermixing was observed leading to the formation of homogeneous Cu 6Sn5 layer. There is no indication of the appearance of the Cu3Sn phase. This offers a way for solid phase soldering at low temperatures, i.e. to produce homogeneous Cu6Sn5 intermediate layer of several tens of nanometers during reasonable time (in the order of hours or less). From the detailed analysis of the growth of the planar reaction layer, formed at the initial interface in Sn(100 nm)/Cu(50 nm) system, the value of the parabolic growth rate coefficient at room temperature is 2.3 x 10-15 cm2/s. In addition, the overall increase of the composition near to the substrate inside the Cu film was interpreted by grain boundary diffusion induced solid state reaction: the new phase formed along the grain boundaries and grew perpendicular to the boundary planes. From the initial slope of the composition versus time function, the interface velocity during this reaction was estimated to be about 0.5 nm/h.
Filtering After Shading With Stochastic Texture Filtering
Creators: name: Pharr, Matt
name: Wronski, Bartlomiej
name: Salvi, Marco
name: Fajardo, Marcos
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Graphics (cs.GR)
subject: FOS: Computer and information sciences

description: 2D texture maps and 3D voxel arrays are widely used to add rich detail to the surfaces and volumes of rendered scenes, and filtered texture lookups are integral to producing high-quality imagery. We show that applying the texture filter after evaluating shading generally gives more accurate imagery than filtering textures before BSDF evaluation, as is current practice. These benefits are not merely theoretical, but are apparent in common cases. We demonstrate that practical and efficient filtering after shading is possible through the use of stochastic sampling of texture filters.
 Stochastic texture filtering offers additional benefits, including efficient implementation of high-quality texture filters and efficient filtering of textures stored in compressed and sparse data structures, including neural representations. We demonstrate applications in both real-time and offline rendering and show that the additional error from stochastic filtering is minimal. We find that this error is handled well by either spatiotemporal denoising or moderate pixel sampling rates.
description: arXiv admin note: substantial text overlap with arXiv:2305.05810
The impact of vaccination and outpatient treatment on the economic burden of covid-19 in the United States omicron era: a systematic literature review
Creators: name: Pierre, Vicki
name: Draica, Florin
name: Di Fusco, Manuela
name: Yang, Jingyan
name: Nunez-Gonzalez, Solange
name: Kamar, Joanna
name: Lopez, Santiago
name: Moran, Mary M
name: Nguyen, Jennifer
name: Alvarez, Piedad
name: Cha-Silva, Ashley
name: Gavaghan, Meghan
name: Yehoshua, Alon
name: Stapleton, Naomi
name: Burnett, Heather
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: To identify and synthesize evidence regarding how coronavirus disease 2019 (COVID-19) interventions, including vaccines and outpatient treatments, have impacted healthcare resource use (HCRU) and costs in the United States (US) during the Omicron era. A systematic literature review (SLR) was performed to identify articles published between 1 January 2021 and 10 March 2023 that assessed the impact of vaccination and outpatient treatment on costs and HCRU outcomes associated with COVID-19. Screening was performed by two independent researchers using predefined inclusion/exclusion criteria. Fifty-eight unique studies were included in the SLR, of which all reported HCRU outcomes, and one reported costs. Overall, there was a significant reduction in the risk of COVID-19-related hospitalization for patients who received an original monovalent primary series vaccine plus booster dose vs. no vaccination. Moreover, receipt of a booster vaccine was associated with a lower risk of hospitalization vs. primary series vaccination. Evidence also indicated a significantly reduced risk of hospitalizations among recipients of nirmatrelvir/ritonavir (NMV/r), remdesivir, sotrovimab, and molnupiravir compared to non-recipients. Treated and/or vaccinated patients also experienced reductions in ICU admissions, length of stay, and emergency department (ED)/urgent care clinic encounters. The identified studies may not represent unique patient populations as many utilized the same regional/national data sources. Synthesis of the evidence was also limited by differences in populations, outcome definitions, and varying duration of follow-up across studies. Additionally, significant gaps, including HCRU associated with long COVID and various high-risk populations and cost data, were observed. Despite evidence gaps, findings from the SLR highlight the significant positive impact that vaccination and outpatient treatment have had on HCRU in the US, including periods of Omicron predominance. Continued research is needed to inform clinical and policy decision-making in the US as COVID-19 continues to evolve as an endemic disease.
An examination of Gilbert and Sullivan's contribution to the emerging common culture of Victorian England, 1871-1896
Creators: name: Ayers, Christopher Vivian
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The thesis examines the light operas of Gilbert and Sullivan, and argues that their popularity depended upon their being a part of an emerging common culture. This common culture was the product of social and economic change which had created the circumstances whereby people of all classes were permitted to share in the process of cultural selection. This replaced the earlier system where the socially dominant class directed cultural activities. In Victorian England, the influence of middle class values was nevertheless particularly evident on music. The preference for choral music of a religious nature and of German orchestral music reflected these values. However, the light operas succeeded in attracting a new audience of people from all social levels. Thus a new market for light musical entertainment had emerged and it was the successful exploitation of this market which suggests that the operas were the products rather than the initiators of change. Because of this, both the preferences of the audience and the opinions of the critics in newspapers and journals strongly influenced both artists. Sullivan's choice of musical idiom was directed by social attitudes towards music, whilst Gilbert's satirical comments reflected contemporary social values. Consequently, the operas indicate a dramatic change in the cultural pattern and provide a record or documentary of Victorian society.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome III, Cart. 187 (11 H 72), f. 0069r
Creators: name: de la Côte d'Or, Archives départementales
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome III, Archives départementales de la Côte-d'Or, Cart. 187 (11 H 72), f. 0069r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome III, Archives départementales de la Côte-d'Or, Cart. 187 (11 H 72), f. 0069r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Assessing the impact of single or short-term administration on a therapy’s cost-effectiveness: a hypothetical disease-agnostic model
Creators: name: Klimchak, Alexa C.
name: Sedita, Lauren E.
name: Gooch, Katherine L.
name: Malone, Daniel C.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Assessing the value of single or short-term therapies (SSTs) within traditional cost-effectiveness analyses (CEAs) has been a topic of discussion as the number of SSTs increases, particularly regarding the effect of discounting on valuation. To quantify the impact of discounting in economic evaluations, a CEA of a hypothetical SST and equivalent chronic therapy was conducted using standard methods. A lifetime Markov model was developed for a hypothetical chronic, progressive disease that could be treated with an SST, chronic therapy, or no novel treatment, termed standard of care (SoC). Incremental cost-effectiveness ratios (ICERs) with quality-adjusted life years (QALYs) comparing SST vs. SoC and an equivalent chronic therapy vs. SoC were assessed from a payer perspective. Both treatments had equal benefits and undiscounted lifetime costs; 3% discounting was applied to costs/benefits in the base case, and the impact of discounting was assessed. In the base case example, both the SST and equivalent chronic therapy vs. SoC had ICERs of $86,000/QALY without discounting. With 3% discounting, the ICER for the SST increased by 116% ($186,000/QALY) while the ICER for the chronic therapy increased by 10% ($95,000/QALY) despite equal clinical benefit. In scenario analyses, the ICER of the SST was consistently higher than the equivalent chronic therapy across a range of assumptions/inputs. Varying the cost/benefit discount rates had a greater impact on the SST. Differences in the ICERs between the therapies increased with increasing life expectancy/time horizon. The simple model structure may not be reflective of acute or more complex diseases. Also, the scenario of perfect equivalency in efficacy and lifetime costs is hypothetical. This quantitative assessment showed the extent to which SST CEAs are highly sensitive to discounting, resulting in worse value assessments for SSTs than equivalent chronic therapies.
title: 03_0381
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Benefits of MR-proADM-guided decision-making in the emergency department: clinical and economic evaluation in Italy, Germany, Spain, and the UK
Creators: name: Porta, Camilla
name: Houshmand, Hirad
name: Povero, Massimiliano
name: Pradelli, Lorenzo
name: Monterosso, Filippo
name: Pinciroli, Matteo
name: Schuetze, Tabea
name: Kirsch, Stefan
name: del Castillo, Juan Gonzales
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: In a randomized control trial mid-regional proadrenomedullin (MR-proADM)-guided decision-making has been proven to safely reduce hospital admissions based on an accurate assessment of disease severity in the Emergency Department (ED). This study aimed to assess the impact of a MR-proADM-Guided Triage (MR-GT) versus standard Hospital Triage (HT) on clinical and economic outcomes in ED patients with suspected infection in Spain, Italy, Germany, and the UK, using Patient-Level Data (PLD) from two observational studies. PLD was collected from patients enrolled at a Spanish hospital during two observational studies. Logistic regression was used to identify predictors of hospitalization. A patient-level simulation model was subsequently developed to evaluate the clinical and economic impact of MR-GT versus HT using results from the statistical analysis and country-specific cost data from the published literature. Probabilistic and deterministic sensitivity analyses were carried out. Four hundred seventy-three patients were enrolled in this study. MR-proADM had the strongest association with hospital admission, followed by age and National Early Warning Score (NEWS). In the simulation model, MR-GT was associated with an overall reduction in unnecessary hospitalization relative to HT, equal to 22.6 percentage points (40.9% vs 63.5%). In addition, the use of MR-GT would reduce the total hospital cost per patient presenting to the ED with suspected infection by roughly 30%, with a mean cost saving per patient of €626, €1,484, €1,154, and £1,113 in Spain, Italy, Germany, and the UK respectively. The robustness of these findings was confirmed by sensitivity analyses. The statistical analyses were not performed on the same population simulated in the model. Clinical input parameters were assumed to be the same for all countries. MR-proADM showed to be the main predictor of hospitalization. A MR-proADM decision algorithm provides cost savings in Spain, Italy, Germany, and the UK.
MOESM1 of Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer
Creators: name: Wu, Huan
name: Li, Rongrong
name: Zhang, Zhiwei
name: Jiang, Huiyang
name: Ma, Hanlin
name: Yuan, Cunzhong
name: Sun, Chenggong
name: Li, Yingwei
name: Kong, Beihua
Publisher: name: figshare
Year: 2019
Subjects: Biophysics
Biochemistry
Cell Biology
Molecular Biology
Chemical Sciences not elsewhere classified
Cancer

description: Additional file 1: Fig. S1. HE staining and immunohistochemistry (IHC) staining of kallistatin in xenograft tumour tissues. Fig. S2. Colony formation assays were performed to evaluate the colony formation ability of A2780 and UWB1.289 cells treated with different doses of cisplatin. #p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001.
Topological phase transitions in an inverted InAs/GaSb quantum well driven by tilted magnetic fields
Creators: name: Hsu, Hsiu-Chuan
name: Jhang, Min-Jyun
name: Chen, Tsung-Wei
name: Guo, Guang-Yu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The helical edge states in a quantum spin Hall insulator are presumably protected by time- reversal symmetry. However, even in the presence of magnetic field which breaks time-reversal symmetry, the helical edge conduction can still exist, dubbed as pseudo quantum spin Hall effect. In this work, the effects of the magnetic fields on the pseudo quantum spin Hall effect and the phase transitions are studied. We show that an in-plane magnetic field drives a pseudo quantum spin Hall state to metallic state at a high field. Moreover, at a fixed in-plane magnetic field, an increasing out-of-plane magnetic field leads to a reentrance of pseudo quantum spin Hall state in an inverted InAs/GaSb quantum well. The edge state probability distribution and Chern numbers are calculated to verify that the reentrant states are topologically nontrivial. The origin of the reentrant behavior is attributed to the nonmonotonic bending of Landau levels and the Landau level mixing caused by the orbital effect induced by the in-plane magnetic field. The robustness to disorder is demonstrated by the numerically calculated quantized conductance for disordered nanowires within Landauer-Büttiker formalism.
Baade's window with APOGEE: Metallicities, ages and chemical abundances
Creators: name: Schultheis, M.
name: Rojas-Arriagada, A.
name: Pérez, A. E. García
name: Jönsson, H.
name: Hayden, M.
name: Nandakumar, G.
name: Cunha, K.
name: Prieto, C. Allende
name: Holtzman, J. A.
name: Beers, T. C.
name: Bizyaev, D.
name: Brinkmann, J.
name: Carrera, R.
name: Cohen, R. E.
name: Geisler, D.
name: Hearty, F. R.
name: Fernández-Trincado, J. G.
name: Maraston, C.
name: Minniti, D.
name: Nitschelm, C.
name: Roman-Lopes, A.
name: Schneider, D. P.
name: Tang, B.
name: Villanova, S.
name: Zasowski, G.
name: Majewski, S. R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Baade's window (BW) is one of the most observed Galactic bulge fields in terms of chemical abundances. Due to its low and homogeneous interstellar absorption it is considered as a calibration field for Galactic bulge studies. In the era of large spectroscopic surveys, calibration fields such as BW are necessary to cross calibrate the stellar parameters and individual abundances of the APOGEE survey. We use the APOGEE BW stars to derive their metallicity distribution function (MDF) and individual abundances, for $α$- and iron-peak elements of the APOGEE ASPCAP pipeline (DR13), as well as the age distribution for stars in BW. We determine the MDF of APOGEE stars in BW and find a remarkable agreement with that of the Gaia-ESO survey (GES). Both exhibit a clear bimodal distribution. We also find that the Mg-metallicity planes of both surveys agree well, except for the metal-rich part ([Fe/H] >0.1), where APOGEE finds systematically higher Mg abundances with respect to the GES. The ages based on the [C/N] ratio reveal a bimodal age distribution, with a major old population at 10 Gyr, with a decreasing tail towards younger stars. A comparison between APOGEE estimates and stellar parameters, and those determined by other sources reveals detectable systematic offsets, in particular for spectroscopic surface gravity estimates. In general, we find a good agreement between individual abundances of O, Na, Mg, Al, Si, K, Ca, Cr, Mn, Co, and Ni from APOGEE with that of literature values. We have shown that in general APOGEE data show a good agreement in terms of MDF and individual chemical abundances with respect to literature works. Using the [C/N] ration we found a significant fraction of young stars in BW which is in agreement with the model of Haywood et al. (2016).
description: 14 pages, 15 figure, accepted for Astronomy&Astrophysics
Quantum-optical trapping of nanodiamonds containing NV centres
Creators: name: Roberts, Reece P.
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Optical trapping offers a non-contact, non-destructive tool for manipulating and handling particles from micron sized particles down to individual atoms with light. One can distinguish two different applications to optical trapping. The first relying on the ability to trap small particles (from tens of nm to tens of μm); and the second one related to the confinement and cooling of atoms or collections of atoms. Until now there has been no system that combines the forces due to both classical trapping and atom trapping as they are usually contained in completely separate parameter regimes even though both of these trapping applications arise from the same force. The force is the result of the interaction of the polarisability of the trapped object, which depends directly on the dipole strength, with the electric field of the trapping laser. In the case of classical trapping, the force acts on an induced dipole caused by the electric field on the object, whereas, in the case of atom trapping the induced dipole arises from the transitions present in the electronic structure. In this way, optically trapped nanoparticles containing embedded optical defects brings about new regimes of trapping and cooling nanoparticles. This new quantum-optical trap allows well established techniques from atom trapping to be applied to the nanoparticles. The result is a quantum-optical trap showing capabilities with much higher trapping strengths and therefore enhanced control for manipulation. The quantum-optical trap also leads to the direct characterisation of the solid state transition properties of the embedded optical defects through force measurements of the trapped nanoparticle. In addition, in the future by applying well established techniques from atom trapping and cold atom physics to the optically trapped particle we can produce a dramatically stronger trap with the potential to cool the nanoparticle centre of mass motion down to its quantum ground state. In this thesis I focused on identifying the trapping forces on the optical defects inside of optically trapped nanoparticles. I developed an experimental setup and procedure to isolate, trap and reliably measure the trapping behaviour of nanoparticles as a platform for investigating the quantum forces on optical defects in nanodiamonds, specifically the quantum force due to the 1042nm metastable transition of the nitrogen vacancy centre.
Additional file 1: of Characterization of glycosylphosphatidylinositol biosynthesis defects by clinical features, flow cytometry, and automated image analysis
Creators: name: Knaus, Alexej
name: Pantel, Jean
name: Pendziwiat, Manuela
name: Nurulhuda Hajjir
name: Zhao, Max
name: Tzung-Chien Hsieh
name: Schubach, Max
name: Gurovich, Yaron
name: Fleischer, Nicole
name: JĂ¤Ger, Marten
name: KĂśhler, Sebastian
name: Muhle, Hiltrud
name: Korff, Christian
name: MĂ¸Ller, Rikke
name: Bayat, Allan
name: Calvas, Patrick
name: Chassaing, Nicolas
name: Warren, Hannah
name: Skinner, Steven
name: Louie, Raymond
name: Evers, Christina
name: Bohn, Marc
name: Hans-JĂźrgen Christen
name: Born, Myrthe Van Den
name: Obersztyn, Ewa
name: Charzewska, Agnieszka
name: Endziniene, Milda
name: KortĂźm, Fanny
name: Brown, Natasha
name: Robinson, Peter
name: Helenius Schelhaas
name: Weber, Yvonne
name: Helbig, Ingo
name: Mundlos, Stefan
name: Horn, Denise
name: Krawitz, Peter
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Supplemental tables and figures. (DOCX 1270 kb)
Cost analysis of disease including treatment with dalbavancin in a Spanish hospital: ECODAL ANALYSIS
Creators: name: Valerio, Maricela
name: Veintimilla, Cristina
name: Rodríguez, Carmen
name: de la Villa, Sofía
name: Sánchez-Somolinos, Mar
name: Cerezales, Mónica
name: Crespo, Carlos
name: Rodríguez, Sara
name: Adán, Iván
name: Chamorro, Esther
name: Rosselló, Irantzu
name: Muñoz, Patricia
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Cancer
subject: Science Policy
subject: Plant Biology
subject: Virology

description: Dalbavancin is an antibiotic with activity against gram-positive bacteria that allows early discharge of patients requiring intravenous therapy. Outpatient treatment helps offset hospitalisation costs associated with standard intravenous treatment. Our objective was to assess the cost of disease management, including treatment with dalbavancin, in a Spanish hospital for 1 year, and the hypothetical costs associated with treatment with other therapeutic alternatives to dalbavancin. A single-centre, observational, retrospective post-hoc analysis was conducted based on electronic medical records analysing all patients who received dalbavancin treatment throughout 1 year; cost analysis was performed for the whole process. In addition, three scenarios designed on the basis of real clinical practice by clinical experts were hypothesised: (i) individual therapeutic alternative to dalbavancin, (ii) all patients treated with daptomycin, and (iii) all days of dalbavancin as outpatient treatment transformed into hospital stay. Costs were obtained from the hospital. Thirty-four patients were treated with dalbavancin; their mean age was 57.9 years, and 70.6% were men. The main reasons for dalbavancin use were outpatient management (61.7%, n = 21) and ensuring treatment adherence (26.5%, n = 9). The main indications were: osteoarticular infection (32.4%) and infective endocarditis (29.4%). One-half (50%) of the infections were due to Staphylococcus aureus (23.5% were methicillin resistant). All patients achieved clinical resolution, and no costs associated with dalbavancin-associated adverse events or re-admissions were reported. The mean total cost of treatment was 22,738€ per patient, with the greatest expenditures in interventions (8,413€) and hospital stay (6,885€). The mean cost of dalbavancin treatment was 3,936€; without dalbavancin, this cost could have been increased to 3,324–11,038€ depending on the scenario, mainly due to hospital stays. Limited sample size obtained from a single centre. The economic impact of the management of these infections is high. The cost of dalbavancin is offset by the decreased length of stay.
Hybrid Superconductor-Quantum Point Contact Devices using InSb Nanowires
Creators: name: Gill, S. T.
name: Damasco, J.
name: Car, D.
name: Bakkers, E. P. A. M.
name: Mason, N.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Proposals for studying topological superconductivity and Majorana bound states in nanowires proximity coupled to superconductors require that transport in the nanowire is ballistic. Previous work on hybrid nanowire-superconductor systems has shown evidence for Majorana bound states, but these experiments were also marked by disorder, which disrupts ballistic transport. In this letter, we demonstrate ballistic transport in InSb nanowires interfaced directly with superconducting Al by observing quantized conductance at zero-magnetic field. Additionally, we demonstrate that the nanowire is proximity coupled to the superconducting contacts by observing Andreev reflection. These results are important steps for robustly establishing topological superconductivity in InSb nanowires.
title: ADCO, Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Cart. 143 (7 H 7), 153 fol, f. 0156r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0156r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0156r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb137389344
description: Provenance: abbaye de Molesme
description: Provenance: http://www.wikidata.org/entity/Q334044
Additional file 5: Figure S1. of De novo transcriptome assembly, annotation and comparison of four ecological and evolutionary model salmonid fish species
Creators: name: Carruthers, Madeleine
name: Yurchenko, Andrey
name: Augley, Julian
name: Adams, Colin
name: Herzyk, Pawel
name: Elmer, Kathryn
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Comparison of full-length transcript reconstruction between the four current assemblies and three previously published transcriptomes; Magnanou et al.â s Arctic charr assembly [34], and the PhyloFish DB brown trout and European whitefish assemblies [35]. Cumulative number of unique matching proteins that aligned to the NCBI protein database for Atlantic salmon (GCF_000233375.1) at a given coverage: Atlantic salmon (yellow), brown trout (green), Arctic charr (blue), European whitefish (red), Magnanou et al. Arctic charr transcriptome (black), PhyloFish brown trout (dark grey), and PhyloFish European whitefish (light grey). (PDF 35Â kb)
Additional file 4: Figure S4. of α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism
Creators: name: Yun, Seung
name: Donghoon Kim
name: Sangjune Kim
name: SangMin Kim
name: Senthilkumar Karuppagounder
name: Seung-Hwan Kwon
name: Saebom Lee
name: Tae-In Kam
name: Suhyun Lee
name: Sangwoo Ham
name: Park, Jae
name: Valina Dawson
name: Dawson, Ted
name: Yunjong Lee
name: Ko, Han
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology

description: MPTP-induced α-synuclein oligomer. a Filter trap soluble-α- synuclein oligomer species assay from ventral midbrain of WT and GBA +/L444P mice with or without MPTP. Error bars represent the mean ± S.E.M. (n = four mice per group). Two-way ANOVA was used for statistical analysis followed by post-hoc Bonferroni test for multiple group comparison. ***P
Scaling fish energetics from individuals to communities
Creators: name: Rosado, Diego Barneche
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Two distinct biological currencies - energy and materials - are essential to life because both are required for the maintenance, growth and reproduction of organisms. Modelling ecological phenomena on the basis of these currencies therefore holds potential for developing a deeper understanding of how the availability of energy and materials in the environment constrains life, in all its diversity, across space and time. In this dissertation, I use the Metabolic Theory of Ecology (MTE) as a framework to explore how individual energetics influences biological processes at distinct levels of organization, from individuals to communities. Particularly, I explore how body mass, environmental temperature, and other variables constrain (i) metabolic rates and growth rates of individuals, and thereby influence (ii) densities of populations at different trophic levels and (iii) the standing biomass and energy fluxes of communities that differ substantially in species diversity. I use fishes to address these questions because they encompass the highest species richness among vertebrates, they encompass more than seven orders of magnitude in body mass, and they occupy diverse habitats that vary substantially in thermal regime across the globe. At the individual level, MTE predictions are generally well supported, although deviations attributable to differences among taxa are clearly noted. By contrast, at the population and community levels, while I do find evidence of energetic constraints, deviations from MTE-derived predictions are frequently observed, highlighting the importance of factors other than individual energetics. I conclude by discussing the implications of these findings to climate change biology and ecosystem dynamics, and highlight avenues for future research.