cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Atomic-scale 3D imaging of individual dopant atoms in a complex oxide
Creators: name: Hunnestad, K. A.
name: Hatzoglou, C.
name: Khalid, Z. M.
name: Vullum, P. E.
name: Yan, Z.
name: Bourret, E.
name: van Helvoort, A. T. J.
name: Selbach, S. M.
name: Meier, D.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A small percentage of dopant atoms can completely change the physical properties of the host material. For example, chemical doping controls the electronic transport behavior of semiconductors and gives rise to a wide range of emergent electric and magnetic phenomena in oxides. Imaging of individual dopant atoms in lightly doped systems, however, remains a major challenge, hindering characterization of the site-specific effects and local dopant concentrations that determine the atomic-scale physics. Here, we apply atom-probe tomography (APT) to resolve individual Ti atoms in the narrow band gap semiconductor ErMnO3 with a nominal proportion of 0.04 atomic percent. Our 3D imaging measures the Ti concentration at the unit cell level, providing quantitative information about the dopant distribution within the ErMnO3 crystal lattice. High-resolution APT maps reveal the 3D lattice position of individual Ti atoms, showing that they are located within the Mn layers with no signs of clustering or other chemical inhomogeneities. The 3D atomic-scale visualization of individual dopant atoms provides new opportunities for the study of local structure-property relations in complex oxides, representing an important step toward controlling dopant-driven quantum phenomena in next-generation oxide electronics.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 6 (72 b)]
Creators: name: , Margarita
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1431
Subjects: subject: Sonstige weltliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Margarita, Tochter des verstorbenen Abraminus de Monestirolo, Witwe des Laurentius de Foliatis sowie Mutter und Vormund der Geschwister Johanna und Abraminus de Foliatis, beide Kinder des genannten Laurentius, aus der Nachbarschaft St. Vitalis in Cremona fertigt in Gegenwart des Augustinus Paulus de Oliariis, Doktor der Rechte und derzeitiger vicarius sowie iudex rationis des Podestà Petrus de Raymondis von Cremona, ein Inventar der Güter ihrer Kinder an.
NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells
Creators: name: Sun, Yi-Ping
name: Cheng, Zhou-Li
name: Zhao, Di
name: Li, Meng-Tian
name: Lei, Qun-Ying
name: Zou, Shao-Wu
name: Xiong, Yue
name: Mo, Yan
name: Guan, Kun-Liang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: High aldehyde dehydrogenase (ALDH) activity is a marker commonly used to isolate stem cells, particularly breast cancer stem cells (CSCs). Here, we determined that ALDH1A1 activity is inhibited by acetylation of lysine 353 (K353) and that acetyltransferase P300/CBP–associated factor (PCAF) and deacetylase sirtuin 2 (SIRT2) are responsible for regulating the acetylation state of ALDH1A1 K353. Evaluation of breast carcinoma tissues from patients revealed that cells with high ALDH1 activity have low ALDH1A1 acetylation and are capable of self-renewal. Acetylation of ALDH1A1 inhibited both the stem cell population and self-renewal properties in breast cancer. Moreover, NOTCH signaling activated ALDH1A1 through the induction of SIRT2, leading to ALDH1A1 deacetylation and enzymatic activation to promote breast CSCs. In breast cancer xenograft models, replacement of endogenous ALDH1A1 with an acetylation mimetic mutant inhibited tumorigenesis and tumor growth. Together, the results from our study reveal a function and mechanism of ALDH1A1 acetylation in regulating breast CSCs.
Understanding the $p/π$ ratio at LHC due to QCD mass spectrum
Creators: name: Noronha-Hostler, Jacquelyn
name: Greiner, Carsten
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Thermal fits have consistently reproduced the experimental particles yields of heavy ion collisions, however, the proton to pion ratio from ALICE Pb+Pb $\sqrt{s_{NN}}=2.76$ TeV is over-predicted by thermal models- known at the $p/π$ puzzle. Here we test the relevance of the extended mass spectrum, i.e., include Hagedorn states (resonances that follow an exponential mass spectrum and have very short life times) on the $p/π$ puzzle. We find that the extended mass spectrum is able to reproduce particle ratios at both RHIC and the LHC as well as being able to match the lower $p/π$ ratio at the LHC through dynamical chemical equilibration.
description: 4 pages, 2 figures
The effect of price regulation on the performances of industrial symbiosis: a case study on district heating
Creators: name: Sacchi, Romain
name: Ramsheva, Yana Konstantinova
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2018

description: This study of the district heating system of Aalborg (Denmark) analyses how fiscal instruments affect the extent excess heat recovery helps reduce the carbon footprint of heat. It builds on a supply-and-demand framework and characterizes the changes in excess heat supply with consequential life cycle assessment in reference to one gigajoule distributed. The heat supply curve is defined through ten scenarios, which represent incremental shares of excess heat as the constraints of the said legal instruments are lifted. The heat demand curve follows the end-users’ response to price changes. The most ambitious scenario doubles the amount of excess heat supplied and reduces the heat carbon footprint by 90% compared to current level, for an end-user price increase of 41%. The price increase results from a higher supply of excess heat at a higher price and an unchanged purchase cost from the coal-fired CHP plant despite a lower supply. This highlights the necessity of a flexible supplier when the share of recovered excess heat is high.
description: International Journal of Sustainable Energy Planning and Management, Vol 14 (2017)
The Effects of Orbital Inclination on the Scale Size and Evolution of Tidally Filling Star Clusters
Creators: name: Webb, Jeremy J.
name: Sills, Alison
name: Harris, William E.
name: Hurley, Jarrod R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We have performed N-body simulations of tidally filling star clusters with a range of orbits in a Milky Way-like potential to study the effects of orbital inclination and eccentricity on their structure and evolution. At small galactocentric distances Rgc, a non-zero inclination results in increased mass loss rates. Tidal heating and disk shocking, the latter sometimes consisting of two shocking events as the cluster moves towards and away from the disk, help remove stars from the cluster. Clusters with inclined orbits at large Rgc have decreased mass loss rates than the non-inclined case, since the strength the disk potential decreases with Rgc. Clusters with inclined and eccentric orbits experience increased tidal heating due to a constantly changing potential, weaker disk shocks since passages occur at higher Rgc, and an additional tidal shock at perigalacticon. The effects of orbital inclination decrease with orbital eccentricity, as a highly eccentric cluster spends the majority of its lifetime at a large Rgc. The limiting radii of clusters with inclined orbits are best represented by the rt of the cluster when at its maximum height above the disk, where the cluster spends the majority of its lifetime and the rate of change in rt is a minimum. Conversely, the effective radius is independent of inclination in all cases.
description: 9 pages, 9 figures, Accepted for publication in MNRAS
Assessment of kinetic theories for moderately dense granular binary mixtures: Shear viscosity coefficient
Creators: name: Chamorro, Moisés García
name: Garzó, Vicente
Publisher: name: arXiv
Year: 2022
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Two different kinetic theories [J. Solsvik and E. Manger (SM-theory), Phys. Fluids \textbf{33}, 043321 (2021) and V. Garzó, J. W. Dufty, and C. M. Hrenya (GDH-theory), Phys. Rev. E \textbf{76}, 031303 (2007)] are considered to determine the shear viscosity $η$ for a moderately dense granular binary mixture of smooth hard spheres. The mixture is subjected to a simple shear flow and heated by the action of an external driving force (Gaussian thermostat) that exactly compensates the energy dissipated in collisions. The set of Enskog kinetic equations is the starting point to obtain the dependence of $η$ on the control parameters of the mixture: solid fraction, concentration, mass and diameter ratios, and coefficients of normal restitution. While the expression of $η$ found in the SM-theory is based on the assumption of Maxwellian distributions for the velocity distribution functions of each species, the GDH-theory solves the Enskog equation by means of the Chapman--Enskog method to first order in the shear rate. To assess the accuracy of both kinetic theories, the Enskog equation is numerically solved by means of the direct simulation Monte Carlo (DSMC) method. The simulation is carried out for a mixture under simple shear flow, using the thermostat to control the cooling effects. Given that the SM-theory predicts a vanishing kinetic contribution to the shear viscosity, the comparison between theory and simulations is essentially made at the level of the collisional contribution $η_c$ to the shear viscosity. The results clearly show that the GDH-theory compares with simulations much better than the SM-theory over a wide range of values of the coefficients of restitution, the volume fraction, and the parameters of the mixture (masses, diameters, and concentration).
description: 14 pages; 5 figures; to be published in Phys. Fluids
Bulk-preventing actions for SU(N) gauge theories
Creators: name: Rindlisbacher, Tobias
name: Rummukainen, Kari
name: Salami, Ahmed
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We introduce a one-parameter family of SU(N) gauge actions which, when used in combination with an HMC update algorithm, prevent the gauge system from entering an artificial bulk-"phase". We briefly discuss the mechanism behind the bulk-prevention and present test results for different SU(N) gauge groups.
description: 9 pages, 5 figures, contribution to the 38th International Symposium on Lattice Field Theory, LATTICE2021 26th-30th July, 2021, Zoom/Gather@Massachusetts Institute of Technology
视觉-语言预训练(VLP)技术介绍
Creators: name: Breezedeus
Publisher: name: Zenodo
Year: 2022
Subjects: Vision-Language Pretraining
Multi-modal Learning
视觉-语言预训练
多模态学习

description: 对当前的视觉-语言预训练(Vision-Language Pretraining, VLP) 技术做了概要介绍,也可以看成是对当前多模态学习(Multi-Modal Learning)技术的概要介绍。 可参考对应的 B站分享视频 。 Also can be found: https://github.com/breezedeus/LoveShare .
On the M2-Brane Index on Noncommutative Crepant Resolutions
Creators: name: Cirafici, Michele
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: On certain M-theory backgrounds which are a circle fibration over a smooth Calabi-Yau, the quantum theory of M2 branes can be studied in terms of the K-theoretic Donaldson-Thomas theory on the threefold. We extend this relation to noncommutative crepant resolutions. In this case the threefold develops a singularity and classical smooth geometry is replaced by the algebra of paths of a certain quiver. K-theoretic quantities on the quiver representation moduli space can be computed via toric localization and result in certain rational functions of the toric parameters. We discuss in particular the case of the conifold and certain orbifold singularities.
description: 38 pages, two Mathematica notebooks are included with the paper; v2 typos corrected; v3 typos corrected, presentation improved, published version
p16INK4a reporter mice reveal age-promoting effects of environmental toxicants
Creators: name: Burd, Christin E.
name: Sharpless, Norman E.
name: Krishnamurthy, Janakiraman
name: Alb, James G.
name: Tilley, Stephen
name: Sorrentino, Jessica A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: While murine-based systems to identify cancer-promoting agents (carcinogens) are established, models to identify compounds that promote aging (gerontogens) have not been described. For this purpose, we exploited the transcription of p16INK4a, which rises dynamically with aging and correlates with age-associated disease. Activation of p16INK4a was visualized in vivo using a murine strain that harbors a knockin of the luciferase gene into the Cdkn2a locus (p16LUC mice). We exposed p16LUC mice to candidate gerontogens, including arsenic, high-fat diet, UV light, and cigarette smoke and serially imaged animals to monitor senescence induction. We show that exposure to a high-fat diet did not accelerate p16INK4a expression, whereas arsenic modestly augmented, and cigarette smoke and UV light potently augmented, activation of p16INK4a-mediated senescence. This work provides a toxicological platform to study mammalian aging and suggests agents that directly damage DNA promote molecular aging.
MRI-driven $α-Ω$ dynamos in protoneutron stars
Creators: name: Reboul-Salze, Alexis
name: Guilet, Jérôme
name: Raynaud, Raphaël
name: Bugli, Matteo
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Magnetars are highly magnetized neutron stars that can produce X-ray and soft gamma-ray emissions and that have a dipole of $10^{14}$ G to $10^{15}$ G. A promising mechanism for explaining magnetar formation is magnetic field amplification by the MRI in fast-rotating protoneutron stars (PNS). This scenario is supported by recent global models, which showed that small-scale turbulence can generate a dipole with magnetar-like intensity. However, the impact of buoyancy and density stratification on the efficiency of the MRI in generating a dipole is still unknown. We assess the impact of the density and entropy profiles on the MRI dynamo in a global model of a fast-rotating PNS, which focuses on its outer stratified region that is stable to convection. Using the pseudo-spectral code MagIC, we performed 3D Boussinesq and anelastic MHD simulations in spherical geometry with explicit diffusivities. We performed a parameter study in which we investigate the effect of different approximations and of thermal diffusion. We obtain a self-sustained turbulent MRI-driven dynamo. This confirms most of our previous incompressible results once rescaled for density. The MRI also generates a nondominant equatorial dipole, which represents about 4.3% of the averaged magnetic field strength. Interestingly, in the presence of a density gradient, an axisymmetric magnetic field at large scales oscillates with time, which can be described as a mean-field $αΩ$ dynamo. Buoyancy damps turbulence in the equatorial plane but it has overall a relatively weak influence with a realistic high thermal diffusion. Our results support the ability of the MRI to generate magnetar-like large-scale magnetic fields. They furthermore predict the presence of an $αΩ$ dynamo in the protoneutron star, which could be important to model in-situ magnetic field amplification in core-collapse supernovae. [abridged]
description: Accepted for publication in A&A, 25 pages, 20 figures
Die Enzyklika "Ingruentium Malorum" über das Rosenkranzgebet
Creators: name: Pius XII., Papst
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 6 Nr. 1 (1951): Herder Korrespondenz, Band 6, Heft 1
A closer look at the seesaw-dark matter correspondence
Creators: name: Coy, Rupert
name: Gupta, Aritra
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In an earlier work, we showed that in very simple neutrino portal-like extensions of the Standard Model it is possible to achieve a one-to-one correspondence between dark matter physics and the seesaw parameters controlling the genesis of neutrino masses. Notably, this can occur both when the dark matter is produced via freeze-in and relativistic freeze-out. In this article, we carry out a detailed phenomenological study of such scenarios. Specifically, we find the allowed regions for the neutrino portal coupling within which the correspondence is valid. We further constrain the parameter space from various observational and theoretical considerations. Within this, we derive the distribution function of a doubly frozen-in particle in order to more accurately compute its free-streaming horizon.
description: 22 pages, 3 figures
PTArcade
Creators: name: Mitridate, Andrea
name: Wright, David
name: von Eckardstein, Richard
name: Schröder, Tobias
name: Nay, Jonathan
name: Olum, Ken
name: Schmitz, Kai
name: Trickle, Tanner
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: manual
cluster
new physics
stochastic

description: This is a lightweight manual for PTArcade, a wrapper of ENTERPRISE and ceffyl that allows for easy implementation of new-physics searches in PTA data. In this manual, we describe how to get PTArcade installed (either on your local machine or an HPC cluster). We discuss how to define a stochastic or deterministic signal and how PTArcade implements these signals in PTA-analysis pipelines. Finally, we show how to handle and analyze the PTArcade output using a series of utility functions that come together with PTArcade.
Understanding the local energy transitions process: a systematic review
Creators: name: Selvakkumaran, Sujeetha
name: Ahlgren, Erik O.
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2018

description: The objective of this paper is to better understand the local energy transitions process, given the importance of local energy transitions. A systematic literature search was conducted and 18 core and 18 peripheral papers on local energy transitions were selected. The 18 core papers were assessed using the framework given by Turnheim et. al. [1]. Findings show that local energy transitions have characteristics or features which are not adequately explained by the framework used. Sources of innovation and the innovation in niches in local energy transitions are explained by socio-technical theories such as Strategic Niche Management (SNM) and Multi-Level Perspective (MLP). The pathway dynamics and the normative goals are covered by quantitative modeling studies of local energy transitions. The specific features of local energy transitions which are not adequately analysed by the existing framework are ownerships of transitions, situative governance issues, spatial scale issues, differing priorities and differing institutional structures, along with the analysis of pathway dynamics. A suggestion for extending a framework to analyse local energy transitions is proposed.
description: International Journal of Sustainable Energy Planning and Management, Vol 14 (2017)
Ejendomsdata – forandringer og muligheder
Creators: name: Knudsen, Peter
Publisher: name: Geoforum Perspektiv
Year: 2018

description: I artiklen præsenteres de ændringer der følger af implementeringen af Ejendomsdataprogrammet under Grunddataprogrammet. Der redegøres bl.a. nærmere for implementeringsplanerne, samt muligheder og gevinster for anvendere. Derudover er der fokuseret på sammenhængene med resten af Grunddataprogrammet og den videre drift, vedligeholdelse og videreudvikling af ejendomsdataområdet. Artiklen er udarbejdet i sammenhæng med et indlæg på Kortdage 2017.
description: Geoforum Perspektiv, Vol 16 No 30 (2017): Special issue related to the yearly conference, Kortdage
Methods to speed up  assembly and improve quality by  designing and developing fixtures
Creators: name: Kamal Kant*
name: Madhukar Solanki
Publisher: name: Zenodo
Year: 2023
Subjects: Fixture design, Computer-aided fixture design, Assembly fixture, Accuracy, productivity, Cost, Production time, Production rate.

description: Fixtures are commonly used tools for assembly to hold workpieces proper position. The fixture's positioning accuracy is also an important factor impacting overall accuracy. There are two assembly fixtures one is for rod end bearing assembly and the other is for motorization block assembly fixture. In the assembly of rod end bearing parts, older fixtures had issues with ball alignment in more than 15% of the parts, and most of the parts showed flash, productivity, and low-quality issues. In the motorization block assembly old process fixture was not used and the assembly was manually performed. Manual assembly takes time, increases the chance of the wrong assembly, and damages bearings during hammering. After developing a new fixture, rod end bearing assembly problems with ball alignment, and flash were all resolved, and the product's quality and productivity both increased. In the motorization block assembly, problems with bearing damage during hammering, and wrong assembly were all resolved after developing a new fixture, and increased product quality and productivity both improved. In rod end bearing assembly 500 Qty, the old fixture produces them in 4.16 hours whereas the new fixture does it in 3.19 hours, and the motorization block assembly fixture resulted in enhanced quality, decreased cycle time, higher productivity, and zero bearing damage during hammering. In moto assembly 50 Qty was produced in total during 3.33 hours without fixtures and 1.25 hours of new fixtures.
The Laniakea supercluster of galaxies
Creators: name: Tully, R. Brent
name: Courtois, Helene
name: Hoffman, Yehuda
name: Pomarède, Daniel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Galaxies congregate in clusters and along filaments, and are missing from large regions referred to as voids. These structures are seen in maps derived from spectroscopic surveys that reveal networks of structure that are interconnected with no clear boundaries. Extended regions with a high concentration of galaxies are called 'superclusters', although this term is not precise. There is, however, another way to analyse the structure. If the distance to each galaxy from Earth is directly measured, then the peculiar velocity can be derived from the subtraction of the mean cosmic expansion, the product of distance times the Hubble constant, from observed velocity. The peculiar velocity is the line-of-sight departure from the cosmic expansion and arises from gravitational perturbations; a map of peculiar velocities can be translated into a map of the distribution of matter. Here we report a map of structure made using a catalogue of peculiar velocities. We find locations where peculiar velocity flows diverge, as water does at watershed divides, and we trace the surface of divergent points that surrounds us. Within the volume enclosed by this surface, the motions of galaxies are inward after removal of the mean cosmic expansion and long range flows. We define a supercluster to be the volume within such a surface, and so we are defining the extent of our home supercluster, which we call Laniakea. A key component of this paper is an accompanying movie that can be viewed (also in 3D) and downloaded at http://irfu.cea.fr/laniakea or http://vimeo.com/pomarede/laniakea
description: accompanying video available in 3D, 7 minutes, english/french, closed captions, teaser of 1 minute http://irfu.cea.fr/laniakea
Results and future plans of the MoEDAL experiment
Creators: name: Mitsou, Vasiliki A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The unprecedented collision energy of the LHC has opened up a new discovery frontier. Unfortunately, signs of new physics have yet to be seen. The LHC's first dedicated search experiment, MoEDAL, started data taking for LHC Run 2. MoEDAL is designed to search highly ionising particle avatars of new physics using pp and heavy-ion collisions at the LHC. The planned upgrade for MoEDAL at Run 3 - the MAPP detector (MoEDAL Apparatus for Penetrating Particles) - will extend MoEDAL's physics reach to include feebly interacting and long-lived messengers of physics beyond the Standard Model. This will allow us to explore a number of models of new physics, including dark-sector models, in a complementary way to that of conventional LHC collider detectors. This article focuses on recent results and plans for the LHC Run 3.
description: 9 pages, 7 figures; presented in European Physical Society Conference on High Energy Physics 2021 (EPS-HEP2021), 26-30 July 2021, Germany; to appear in Proceedings of Science (PoS). arXiv admin note: text overlap with arXiv:2111.03036
Die Enzyklika "Sempiternus Rex Christus" zum 1500. Jahresgedächtnis des Konzils von Chalzedon
Creators: name: Pius XII., Papst
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 6 Nr. 1 (1951): Herder Korrespondenz, Band 6, Heft 1
Illuminating long-lived dark vector bosons via exotic Higgs decays at $\sqrt{s} = 13\,{\text {TeV}}$
Creators: name: Elkafrawy, Tamer
name: Hohlmann, Marcus
name: Kamon, Teruki
name: Padley, Paul
name: Kim, Hyunyong
name: Rahmani, Mehdi
name: Dildick, Sven
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The possibility of producing a measurable long-lived dark $Z$ boson, that is assumed to be produced either via its kinetic mixing with the hypercharge gauge boson or via mixing of the observed 125-GeV Higgs boson with the dark Higgs boson, called Higgs mixing, in Run 2 of the Large Hadron Collider (LHC) is investigated. Displaced dimuons in the final state are considered where each of the $Z$ and the dark $Z$ bosons decays directly to a dimuon. The Higgs production cross sections via gluon-gluon fusion at 13 TeV calculated to a combination of next-to-next-to-next-to-leading order with QCD corrections (N$^{3}$LO QCD) and next-to-leading order with electroweak corrections (NLO EW) from the literature are used, while the branching fractions are calculated to NLO by using Monte Carlo simulation in the framework of {\textsc{MadGraph5}}\_aMC@NLO and compared to the available analytical calculations to leading order (LO). Sensitivities of the LHC in Run 2 to such searches are discussed.
description: 6 pages, 4 figures
Solar Flare Ribbon Fronts I: Constraining flare energy deposition with IRIS spectroscopy
Creators: name: Polito, Vanessa
name: Kerr, Graham S.
name: Xu, Yan
name: Sadykov, Viacheslav M.
name: Lorincik, Juraj
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Lower atmospheric lines show peculiar profiles at the leading edge of ribbons during solar flares. In particular, increased absorption of the BBSO/GST \hei~10830~Å line \citep[e.g.][]{Xu2016}, as well as broad and centrally reversed profiles in the spectra of the \mgii~and \cii~lines observed by the \iris~satellite \citep[e.g.][]{Panos2018,Panos2021a} have been reported. In this work, we aim to understand the physical origin of the \iris\ ribbon front line profiles, which seem to be common of many, if not all, flares. To achieve this, we quantify the spectral properties of the \iris~\mgii~ribbon front profiles during four large flares and perform a detailed comparison with a grid of radiative hydrodynamic models using the \radynfp~code. We also studied their transition region counterparts, finding that these ribbon front locations are regions where transition region emission and chromospheric evaporation are considerably weaker compared to other parts of the ribbons. Based on our comparison between the \iris~observations and modelling, our interpretation is that there are different heating regimes at play in the leading and trailing regions of the ribbons. More specifically, we suggest that bombardment of the chromosphere by more gradual and modest non-thermal electron energy fluxes can qualitatively explain the \iris~observations at the ribbon front, while stronger and more impulsive energy fluxes are required to drive chromospheric evaporation and more intense TR emission. Our results provide a possible physical origin for the peculiar behaviour of the \iris~chromospheric lines in the ribbon leading edge and new constraints for the flare models.
Plasma fibronectin supports hemostasis and regulates thrombosis
Creators: name: Wolberg, Alisa S.
name: Rand, Margaret L.
name: Ni, Heyu
name: Kalantari, Jalil
name: Gross, Peter L.
name: Marshall, Alexandra H.
name: Freedman, John
name: Mosher, Deane F.
name: Weitz, Jeffrey I.
name: Wang, Yiming
name: Spring, Christopher M.
name: Reheman, Adili
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Plasma fibronectin (pFn) has long been suspected to be involved in hemostasis; however, direct evidence has been lacking. Here, we demonstrated that pFn is vital to control bleeding in fibrinogen-deficient mice and in WT mice given anticoagulants. At the site of vessel injury, pFn was rapidly deposited and initiated hemostasis, even before platelet accumulation, which is considered the first wave of hemostasis. This pFn deposition was independent of fibrinogen, von Willebrand factor, β3 integrin, and platelets. Confocal and scanning electron microscopy revealed pFn integration into fibrin, which increased fibrin fiber diameter and enhanced the mechanical strength of clots, as determined by thromboelastography. Interestingly, pFn promoted platelet aggregation when linked with fibrin but inhibited this process when fibrin was absent. Therefore, pFn may gradually switch from supporting hemostasis to inhibiting thrombosis and vessel occlusion following the fibrin gradient that decreases farther from the injured endothelium. Our data indicate that pFn is a supportive factor in hemostasis, which is vital under both genetic and therapeutic conditions of coagulation deficiency. By interacting with fibrin and platelet β3 integrin, pFn plays a self-limiting regulatory role in thrombosis, suggesting pFn transfusion may be a potential therapy for bleeding disorders, particularly in association with anticoagulant therapy.
Tuning the hydrogen desorption of Mg(BH$_4$)$_2$ through Zn alloying
Creators: name: Harrison, D.
name: Thonhauser, T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We study the effect of Zn alloying on the hydrogen desorption properties of Mg(BH$_4$)$_2$ using $\it{ab\ initio}$ simulations. In particular, we investigate formation/reaction enthalpies/entropies for a number of compounds and reactions at a wide range of temperatures and Zn concentrations in Mg$_{1-x}$Zn$_x$(BH$_4$)$_2$. Our results show that the thermodynamic stability of the resulting material can be significantly lowered through Zn alloying. We find that e.g. the solid solution Mg$_{2/3}$Zn$_{1/3}$(BH$_4$)$_2$ has a reaction enthalpy for the complete hydrogen desorption of only 25.3 kJ/mol H$_2$$-$a lowering of 15 kJ/mol H$_2$ compared to the pure phase and a corresponding lowering in critical temperature of 123 K. In addition, we find that the enthalpy of mixing is rather small and show that the decrease in reaction enthalpy with Zn concentration is approximately linear.
description: 12 pages including appendix and references, 2 figures
RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction
Creators: name: Pickles, Raymond J.
name: Liesman, Rachael M.
name: DeVincenzo, John P.
name: Yang, Lijuan
name: Luongo, Cindy L.
name: Collins, Peter L.
name: Proia, Alan D.
name: Buchholz, Ursula J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Respiratory syncytial virus (RSV) infection is the major cause of bronchiolitis in young children. The factors that contribute to the increased propensity of RSV-induced distal airway disease compared with other commonly encountered respiratory viruses remain unclear. Here, we identified the RSV-encoded nonstructural 2 (NS2) protein as a viral genetic determinant for initiating RSV-induced distal airway obstruction. Infection of human cartilaginous airway epithelium (HAE) and a hamster model of disease with recombinant respiratory viruses revealed that NS2 promotes shedding of infected epithelial cells, resulting in two consequences of virus infection. First, epithelial cell shedding accelerated the reduction of virus titers, presumably by clearing virus-infected cells from airway mucosa. Second, epithelial cells shedding into the narrow-diameter bronchiolar airway lumens resulted in rapid accumulation of detached, pleomorphic epithelial cells, leading to acute distal airway obstruction. Together, these data indicate that RSV infection of the airway epithelium, via the action of NS2, promotes epithelial cell shedding, which not only accelerates viral clearance but also contributes to acute obstruction of the distal airways. Our results identify RSV NS2 as a contributing factor for the enhanced propensity of RSV to cause severe airway disease in young children and suggest NS2 as a potential therapeutic target for reducing the severity of distal airway disease.
Computational design of novel MAX phase alloys for potential hydrogen storage media combining first principles and cluster expansion methods
Creators: name: Das, Pritam
name: Thekkepat, Krishnamohan
name: Lee, Young-Su
name: Lee, Seung-Cheol
name: Bhattacharjee, Satadeep
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Finding a suitable material for hydrogen storage at ambient atmospheric conditions is challenging for material scientists and chemists. In this work, using a first principles based cluster expansion approach, the hydrogen storage capacity of Ti2AC (A = Al,Ti, Cr, Mn, Fe, Co, Ni, Cu, and Zn) MAX phase and its alloys were studied. We found that hydrogen is energetically stable in Ti-A layers in which the tetrahedral site consisting of one A atom and three Ti atoms is energetically more favorable for hydrogen adsorption than other sites in the Ti-A layer. Ti2CuC has the highest hydrogen adsorption energy than other Ti2AC phases. We find that 83.33% Cu doped Ti2AlxCu1-xC alloy structure is both energetically and dynamically stable and can store 3.66 wt% hydrogen at ambient atmospheric conditions, which is higher than both Ti2AlC and Ti2CuC phase. These findings indicate that the hydrogen capacity of the MAX phase can be significantly improved by doping an appropriate atom species.
Cosmological Dependence of Sterile Neutrino Dark Matter With Self-Interacting Neutrinos
Creators: name: Chichiri, Carlos
name: Gelmini, Graciela B.
name: Lu, Philip
name: Takhistov, Volodymyr
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Unexplored interactions of neutrinos could be the key to understanding the nature of the dark matter (DM). In particular, active neutrinos with new self-interactions can produce keV-mass sterile neutrinos that account for the whole of the DM through the Dodelson-Widrow mechanism for a large range of active-sterile mixing values. This production typically occurs before Big-Bang Nucleosynthesis (BBN) in a yet uncharted era of the Universe. We assess how the mixing range for keV-mass sterile neutrino DM is affected by the uncertainty in the early Universe pre-BBN cosmology. This is particularly relevant for identifying the viable parameter space of sterile neutrino searches allowed by all astrophysical limits, as well as for cosmology, since the detection of a sterile neutrino could constitute the first observation of a particle providing information about the pre-BBN epoch. We find that the combined uncertainties in the early Universe cosmology and neutrino interactions significantly expand the allowed parameter space for sterile neutrinos that can constitute the whole of the DM.
description: 23 pages, 5 figures
Antibiotic resistance in stream: monitoring, modeling and effluent control by photocatalytic disinfection
Creators: name: Antonino, Fiorentino
Publisher: name: Universita degli studi di Salerno
Year: 2015
Subjects: subject: ICAR/03 INGEGNERIA SANITARIA-AMBIENTALE
subject: Acque reflue - Disinfezione
subject: Antibiotici - Resistenza

description: 2013-2014
description: Since the 1940s, the ever-increasing use of antibiotics for human, veterinary and agricultural purposes, contributes to their continuous release into the environment due to incomplete metabolism or due to disposal of unused antibiotics. The concern for the release of antibiotics into the environment isrelated to the development of antibiotic resistance genes (ARGs) and bacteria (ARB), which reduce the therapeutic potential against human and animal pathogens. Urban wastewater treatment plant (UWWTP) effluents, hospital discharges, livestock farms represent today the major contamination sources of surface water from antibiotics and ARB. The consequence is that antibiotics, exerting selective pressure, may facilitate the selection of ARB or the acquisition of resistance genes by horizontal transfer. The aim of this work was to investigate the spread of ARB in the environment, particularly in water system, as well as to minimize the related risk through the investigation of effective wastewater disinfection methods. Accordingly, experimental activity was addressed to (i) the monitoring of ARB in river, (ii) modelling ARB fate in river and (iii) minimize ARB release in river through effective wastewater disinfection. [edited by Author]
SOME SEMANTIC AND STYLISTIC FEATURES OF AUXILIARY WORDS IN MODERN UZBEK AND ENGLISH LANGUAGES.
Creators: name: Rasulova, Inobat
Publisher: name: Zenodo
Year: 2025

description: This article provides an exploration of the meanings and stylistic features of auxiliary words in both Uzbek and English. Auxiliary words play a crucial role within the grammatical framework of these languages; their functions include complementing main words, imparting additional meanings, linking independent words within a sentence, and offering grammatical or syntactic descriptions. The analysis presented herein delves into the similarities and differences of auxiliary words across both languages, with a focus on auxiliary, preposition, conjunction, and particles.
Taxonomy of breast cancer based on normal cell phenotype predicts outcome
Creators: name: Richardson, Andrea
name: Thakkar, Ankita
name: Wang, Bin
name: Ince, Tan A.
name: Schwede, Matthew
name: Tamimi, Rulla M.
name: Kindelberger, David
name: Culhane, Aedin C.
name: Harrell, J. Chuck
name: Santagata, Sandro
name: Woo, Terri
name: Rodig, Scott
name: Ergonul, Ayse
name: Hu, Rong
name: McNamara, George
name: Schnitt, Stuart J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Accurate classification is essential for understanding the pathophysiology of a disease and can inform therapeutic choices. For hematopoietic malignancies, a classification scheme based on the phenotypic similarity between tumor cells and normal cells has been successfully used to define tumor subtypes; however, use of normal cell types as a reference by which to classify solid tumors has not been widely emulated, in part due to more limited understanding of epithelial cell differentiation compared with hematopoiesis. To provide a better definition of the subtypes of epithelial cells comprising the breast epithelium, we performed a systematic analysis of a large set of breast epithelial markers in more than 15,000 normal breast cells, which identified 11 differentiation states for normal luminal cells. We then applied information from this analysis to classify human breast tumors based on normal cell types into 4 major subtypes, HR0–HR3, which were differentiated by vitamin D, androgen, and estrogen hormone receptor (HR) expression. Examination of 3,157 human breast tumors revealed that these HR subtypes were distinct from the current classification scheme, which is based on estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. Patient outcomes were best when tumors expressed all 3 hormone receptors (subtype HR3) and worst when they expressed none of the receptors (subtype HR0). Together, these data provide an ontological classification scheme associated with patient survival differences and provides actionable insights for treating breast tumors.
Buckling of lipidic ultrasound contrast agents under quasi-static load
Creators: name: Chabouh, Georges
name: van Elburg, Benjamin
name: Versluis, Michel
name: Segers, Tim
name: Quilliet, Catherine
name: Coupier, Gwennou
Publisher: name: arXiv
Year: 2022
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Collapse of lipidic ultrasound contrast agents under high-frequency compressive load has been historically interpreted by the vanishing of surface tension. By contrast, buckling of elastic shells is known to occur when costly compressible stress is released through bending. Through quasi-static compression experiments on lipidic shells, we analyze the buckling events in the framework of classical elastic buckling theory and deduce the mechanical characteristics of these shells. They are then compared to that obtained through acoustic characterization.
Axial gravitational perturbations of an infinite static line source
Creators: name: Gleiser, Reinaldo J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we study axial gravitational perturbations of an infinite static line source, represented by a form of the Levi-Civita metric. The perturbations are restricted to axial symmetry but break the cylindrical symmetry of the background metric. We analyze the gauge issues that arise in setting up the appropriate form of the perturbed metric and show that it is possible to restrict to diagonal terms, but that this does not fix the gauge completely. We derive the perturbation equations and show that they can be solved by solving a third order ordinary differential equation for an appropriately chosen function of the perturbed metric coefficients. The set of solutions of this equation contains gauge trivial parts, and we show how to extract the gauge non trivial components. We introduce appropriate boundary conditions on the solutions and show that these lead to a boundary value problem that determines the allowed functional forms of the perturbation modes. The associated eigenvalues determine a sort of "dispersion relation" for the frequencies and corresponding "wave vector" components. The central result of this analysis is that the spectrum of allowed frequencies contains one unstable (imaginary frequency) mode for every possible choice of the background metric. The completeness of the mode expansion in relation to the initial value problem and to the gauge problem is discussed in detail, and we show that the perturbations contain an unstable component for generic initial data, and, therefore, that the Levi-Civita space times are gravitationally unstable. We also include, for completeness, a set of approximate eigenvalues, and examples of the functional form of the solutions.
description: 17 pages, 2 figures
Fremtidens ejendomsvurdering
Creators: name: Colding, Tina Svan
name: Lindegaard, Lasse Skakkebæk
name: Breumlund, Lars
Publisher: name: Geoforum Perspektiv
Year: 2018

description: Det nuværende ejendomsvurderingssystem har historisk set vist sig udfordret på en række områder. Det var oplevelsen, at vurderingerne generelt set var upræcise, uensartede og uigennemskuelige. Ejendomsvurderingerne blev suspenderet tilbage i 2013 – blandt andet på baggrund af kritik fra Rigsrevisionen. I forlængelse af Rigsrevisionens kritik nedsatte den tidligere regering det såkaldte Engbergudvalg, der fik til opgave at komme med anbefalinger til at forbedre ejendomsvurderingssystemet. Engbergudvalget anbefalede i september 2014, at der blev lavet et nyt og gennemsigtigt vurderingssystem baseret på bedre data og med afsæt i tidssvarende statistiske metoder. Blandt de væsentligste anbefalinger til de nye vurderingsmodeller var, at alle vurderinger bør bygge på objektive data og kriterier. Det var udvalgets vurdering, at man blandt andet på baggrund af nye og bedre data, herunder matrikeldata, BBR data, plandata mv. kunne sikre tilstrækkelig høj datakvalitet til, at de kunne tjene som objektivt grundlag i vurderingsøjemed. Udvalget anbefalede derfor, at der blev arbejdet videre på at kvalitetsløfte data, forfine og udvikle nye metoder og variable til det nye ejendomsvurderingssystem.
description: Geoforum Perspektiv, Vol 16 No 30 (2017): Special issue related to the yearly conference, Kortdage