cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the Spectral Form Factor for Random Matrices
Creators: name: Cipolloni, Giorgio
name: Erdős, László
name: Schröder, Dominik
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mathematical Physics (math-ph)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 60B20

description: In the physics literature the spectral form factor (SFF), the squared Fourier transform of the empirical eigenvalue density, is the most common tool to test universality for disordered quantum systems, yet previous mathematical results have been restricted only to two exactly solvable models [Forrester 2020]. We rigorously prove the physics prediction on SFF up to an intermediate time scale for a large class of random matrices using a robust method, the multi-resolvent local laws. Beyond Wigner matrices we also consider the monoparametric ensemble and prove that universality of SFF can already be triggered by a single random parameter, extending the recently proven Wigner-Dyson universality [Cipolloni, Erdős, Schröder 2021] to some larger spectral scales. Remarkably, extensive numerics indicates that our formulas correctly predict the SFF in the entire slope-dip-ramp regime, as customarily called in physics.
description: 33 pages, 3 figures
Preventing and Reversing Vacuum-Induced Optical Losses in High-Finesse Tantalum (V) Oxide Mirror Coatings
Creators: name: Gangloff, Dorian
name: Shi, Molu
name: Wu, Tailin
name: Bylinskii, Alexei
name: Braverman, Boris
name: Gutierrez, Michael
name: Nichols, Rosanna
name: Li, Junru
name: Aichholz, Kai
name: Cetina, Marko
name: Karpa, Leon
name: Jelenković, Branislav
name: Chuang, Isaac
name: Vuletić, Vladan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We study the vacuum-induced degradation of high-finesse optical cavities with mirror coatings composed of SiO$_2$-Ta$_{2}$O$_{5}$ dielectric stacks, and present methods to protect these coatings and to recover their initial quality factor. For separate coatings with reflectivities centered at 370 nm and 422 nm, a vacuum-induced continuous increase in optical loss occurs if the surface-layer coating is made of Ta$_{2}$O$_{5}$, while it does not occur if it is made of SiO$_2$. The incurred optical loss can be reversed by filling the vacuum chamber with oxygen at atmospheric pressure, and the recovery rate can be strongly accelerated by continuous laser illumination at 422 nm. Both the degradation and the recovery processes depend strongly on temperature. We find that a 1 nm-thick layer of SiO$_2$ passivating the Ta$_{2}$O$_{5}$ surface layer is sufficient to reduce the degradation rate by more than a factor of 10, strongly supporting surface oxygen depletion as the primary degradation mechanism.
description: 14 pages, 7 figures
title: A Computer Programming Intervention for Second Grade Math Students
Creators: name: Bagley, Eric B.
Publisher: name: Utah State University
Year: 2022

description: The multiplication algorithms taught to elementary students are made to help students find answers quickly, but why the algorithm works and how it relates to multiplication is not widely known. For example, one intuitive meaning of multiplication is that of iterated, or, repeated, addition. In this paper, we look at the ways a visual, block-based, programming activity uses the concept of iteration to help second-graders learn multiplication. The results of the study observing second-grade students use visual programming and iteration to setup and solve multiplication story problems. We found that generally students enjoyed these activities and found them helpful during the learning process.
(101129) Ada George Kidd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Hippocampal IGF-1 expression, neurogenesis and slowed aging: clues to longevity from mutant mice
Creators: name: Sun, Liou Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Recent studies point out the important role of IGF and insulin-related signaling pathways in the control of longevity of laboratory animals. The Ames dwarf mouse is a murine model of circulating GH and IGF-1 deficiency that exhibits dwarf phenotype characteristics and significantly extends lifespan. It is interesting to know that Ames dwarf mice do not experience an age-related decline in cognitive function when compared to their young counterparts. In this study, the most recent works on local GH and IGF-1 expression in the hippocampus of Ames mice are briefly reviewed.
Association of heat shock proteins with all-cause mortality
Creators: name: Bandinelli, S.
name: Garcia, M. E.
name: Broer, L.
name: Harris, T. B.
name: Franceschini, N.
name: Lunetta, K. L.
name: Atzmon, G.
name: Gudnason, V.
name: Murabito, J. M.
name: Ferrucci, L.
name: Dörr, M.
name: Newman, A. B.
name: Lohman, K. K.
name: Walter, S.
name: Oostra, B. A.
name: Psaty, B. M.
name: Wallaschofski, H.
name: Arnold, A. M.
name: Demerath, E. W.
name: Launer, L. J.
name: Hoffmann, W.
name: Tanaka, T.
name: Karasik, D.
name: Van Duijn, C. M.
name: Rotter, J. I.
name: Tiemeier, H.
name: Kiel, D. P.
name: Homuth, G.
name: Kocher, T.
name: Liu, Y.
name: Hofman, A.
name: Uitterlinden, A. G.
name: Kaplan, R. C.
name: Smith, A. V.
name: Tranah, G. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Experimental mild heat shock is widely known as an intervention that results in extended longevity in various models along the evolutionary lineage. Heat shock proteins (HSPs) are highly upregulated immediately after a heat shock. The elevation in HSP levels was shown to inhibit stress-mediated cell death, and recent experiments indicate a highly versatile role for these proteins as inhibitors of programmed cell death. In this study, we examined common genetic variations in 31 genes encoding all members of the HSP70, small HSP, and heat shock factor (HSF) families for their association with all-cause mortality. Our discovery cohort was the Rotterdam study (RS1) containing 5,974 participants aged 55years and older (3,174 deaths). We assessed 4,430 single nucleotide polymorphisms (SNPs) using the HumanHap550K Genotyping BeadChip from Illumina. After adjusting for multiple testing by permutation analysis, three SNPs showed evidence for association with all-cause mortality in RS1. These findings were followed in eight independent population-based cohorts, leading to a total of 25,007 participants (8,444 deaths). In the replication phase, only HSF2 (rs1416733) remained significantly associated with all-cause mortality. Rs1416733 is a known cis-eQTL for HSF2. Our findings suggest a role of HSF2 in all-cause mortality.Electronic supplementary materialThe online version of this article (doi:10.1007/s11357-012-9417-7) contains supplementary material, which is available to authorized users.
Green Pea Galaxies Reveal Secrets of Ly$α$ Escape
Creators: name: Yang, Huan
name: Malhotra, Sangeeta
name: Gronke, Max
name: Rhoads, James E.
name: Dijkstra, Mark
name: Jaskot, Anne
name: Zheng, Zhenya
name: Wang, Junxian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We analyze archival Ly$α$ spectra of 12 "Green Pea" galaxies observed with the Hubble Space Telescope, model their Ly$α$ profiles with radiative transfer models, and explore the dependence of Ly$α$ escape fraction on various properties. Green Pea galaxies are nearby compact starburst galaxies with [OIII]$λ$5007 equivalent widths of hundreds of Å. All 12 Green Pea galaxies in our sample show Ly$α$ lines in emission, with a Ly$α$ equivalent width distribution similar to high redshift Ly$α$ emitters. Combining the optical and UV spectra of Green Pea galaxies, we estimate their Ly$α$ escape fractions and find correlations between Ly$α$ escape fraction and kinematic features of Ly$α$ profiles. The escape fraction of Ly$α$ in these galaxies ranges from 1.4% to 67%. We also find that the Ly$α$ escape fraction depends strongly on metallicity and moderately on dust extinction. We compare their high-quality Ly$α$ profiles with single HI shell radiative transfer models and find that the Ly$α$ escape fraction anti-correlates with the derived HI column densities. Single shell models fit most Ly$α$ profiles well, but not the ones with highest escape fractions of Ly$α$. Our results suggest that low HI column density and low metallicity are essential for Ly$α$ escape, and make a galaxy a Ly$α$ emitter.
description: 9 figures, ApJ accepted
Acute effects of passive stretching of the plantarflexor muscles on neuromuscular function: the influence of age
Creators: name: Costa, Pablo B.
name: Herda, Ashley A.
name: Herda, Trent J.
name: Ryan, Eric D.
name: Cramer, Joel T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Abstract The acute effects of stretching on peak force (F peak), percent voluntary activation (%VA), electromyographic (EMG) amplitude, maximum range of motion (MROM), peak passive torque, the passive resistance to stretch, and the percentage of ROM at EMG onset (%EMGonset) were examined in 18 young and 19 old men. Participants performed a MROM assessment and a maximal voluntary contraction of the plantarflexors before and immediately after 20 min of passive stretching. F peak (−11 %), %VA (−6 %), and MG EMG amplitude (−9 %) decreased after stretching in the young, but not the old (P > 0.05). Changes in F peak were related to reductions in all muscle activation variables (r = 0.56–0.75), but unrelated to changes in the passive resistance to stretch (P ≥ 0.24). Both groups experienced increases in MROM and peak passive torque and decreases in the passive resistance to stretch. However, the old men experienced greater changes in MROM (P < 0.001) and passive resistance (P = 0.02–0.06). Changes in MROM were correlated to increases in peak passive torque (r = 0.717), and the old men also experienced a nonsignificant greater (P = 0.08) increase in peak passive torque. %EMGonset did not change from pre- to post-stretching for both groups (P = 0.213), but occurred earlier in the old (P = 0.06). The stretching-induced impairments in strength and activation in the young but not the old men may suggest that the neural impairments following stretching are gamma-loop-mediated. In addition, the augmented changes in MROM and passive torque and the lack of change in %EMGonset for the old men may be a result of age-related changes in muscle-tendon behavior.
title: MDCT - pathological Correlation in Colon Adenocarcinoma Staging: Preliminary Experience
Creators: name: Eyheremendy, Eduardo
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Oncology
subject: Colon
subject: CT
subject: Staging
subject: Cancer
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Determine whether preoperative staging with MDCT can predict the TN stage of the...
Age-related changes in the rate of muscle activation and rapid force characteristics
Creators: name: Thompson, Brennan J.
name: Herda, Ashley A.
name: Costa, Pablo B.
name: Herda, Trent J.
name: Ryan, Eric D.
name: Cramer, Joel T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Abstract Declines in muscle size and strength are commonly reported as a consequence of aging; however, few studies have investigated the influence of aging on the rate of muscle activation and rapid force characteristics across the lifespan. This study aims to investigate the effects of aging on the rate of muscle activation and rapid force characteristics of the plantar flexors. Plantar flexion peak force (PF), absolute (peak, 50, and 100–200 ms), and relative (10 %, 30 %, and 50 %) rate of force development (RFD), the rapid to maximal force ratio (RFD/PF), and the rate of electromyography rise (RER) were examined during an isometric maximal voluntary contraction (MVC) in young (age = 22 ± 2 years), middle-aged (43 ± 2 years), and old (69 ± 5 years) men. The old men exhibited lower PF (30.7 % and 27.6 % lower, respectively) and absolute (24.4–55.1 %) and relative (16.4–28.9 %) RFD values compared to the young and middle-aged men (P ≤ 0.03). RER values were similar between the young and old men (P ≥ 0.30); however, RER values were greater for the middle-aged men when compared to the young and old men for the soleus (P < 0.01) and the old men for the medial gastrocnemius (P ≤ 0.02). Likewise, RFD/PF ratios were similar between young and old men (P ≥ 0.26); however, these ratios were greater for the middle-aged men at early (P ≤ 0.03), but not later (P ≥ 0.10), time intervals. The lower PF and absolute and relative RFD values for the old men may contribute to the increased functional limitations often observed in older adults. Interestingly, higher rates of muscle activation and greater early RFD/PF ratios in middle-aged men may be a reflection of physiological alterations in the neuromuscular system occurring in the fifth decade.
Socioeconomic status and the trajectory of self-rated health
Creators: name: McNeill, Ann M.
name: Rosamond, Wayne D.
name: Chang, Patricia P.
name: Suchindran, Chirayath M.
name: Foraker, Randi E.
name: Selvin, Elizabeth
name: Rose, Kathryn M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Background: self-rated health (SRH) likely reflects both mental and physical health domains, and is assessed by asking individuals to describe their health status. Poor SRH is associated with disease incidence and subsequent mortality. Changes in SRH across time in persons with different incident diseases are uncharacterised.
The defocusing quintic NLS in four space dimensions
Creators: name: Dodson, Benjamin
name: Miao, Changxing
name: Murphy, Jason
name: Zheng, Jiqiang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We consider the defocusing quintic nonlinear Schrödinger equation in four space dimensions. We prove that any solution that remains bounded in the critical Sobolev space must be global and scatter. We employ a space-localized interaction Morawetz inequality, the proof of which requires us to overcome the logarithmic failure in the double Duhamel argument in four dimensions.
description: 29 pages
(101130) Mary Dorothea George Kidd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Correlation of preoperative MR imaging staging and histopathology findings in primary cervical carcinoma: a pictorical review
Creators: name: Eyheremendy, Eduardo
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Pelvis
subject: Genital / Reproductive system female
subject: Oncology
subject: MR
subject: Diagnostic procedure
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Review High Resolution Magnetic Resonance (HRMRI) techniques for pelvic evaluation of cervical uterine carcinoma using phased-array coil. Discuss the accuracy of HRMRI for diagnosis and staging of cervical uterine carcinoma. Discuss the correlation...
Baby boomer caregiver and dementia caregiving: findings from the National Study of Caregiving
Creators: name: Dilworth-Anderson, Peggye
name: Moon, Heehyul
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Background: previous studies have well documented the characteristics of baby boomers but less is known about the experiences of boomer caregivers (CGs) of people with dementia.
title: A new look at the hand injuries: role of ultrasound and magnetic resonance imaging
Creators: name: Manzella, Adonis
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Trauma
subject: Neoplasia
subject: Foreign bodies
subject: Education
subject: Ultrasound-Power Doppler
subject: Ultrasound
subject: MR
subject: Musculoskeletal system
subject: Musculoskeletal soft tissue
subject: Extremities

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1- To discuss some of the hand injuries that may cause chronic pain. 2- To describe the imaging features of some ofthe common as well as less frequent soft tissue and bone hand lesions and illustrate them using MRI and...
MPEC 2023-T202 : 2023 TD8
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 TD8

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
(101126) Ada Isabella Ham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Many nodal domains in random regular graphs
Creators: name: Ganguly, Shirshendu
name: McKenzie, Theo
name: Mohanty, Sidhanth
name: Srivastava, Nikhil
Publisher: name: arXiv
Year: 2021
Subjects: subject: Probability (math.PR)
subject: Discrete Mathematics (cs.DM)
subject: Mathematical Physics (math-ph)
subject: Combinatorics (math.CO)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: 05C80, 60B20

description: Let $G$ be a random $d$-regular graph. We prove that for every constant $α> 0$, with high probability every eigenvector of the adjacency matrix of $G$ with eigenvalue less than $-2\sqrt{d-2}-α$ has $Ω(n/$polylog$(n))$ nodal domains.
description: 18 pages. Minor changes to the introduction
Antimicrobial Activity of Edible Electrospun Chitosan/Cellulose Acetate/Gelatin Hybrid Nanofiber Mats Incorporating Eugenol
Creators: name: Tepsorn, Racha
Publisher: name: King Mongkut's Institute of Technology Ladkrabang
Year: 2019
Subjects: antimicrobial nanofibers electrospinning edible electrospun eugenol chitosan

description: Current Applied Science and Technology, 19, 3, 235-247
title: Femoral vascular access-site complications: The role of radiology in diagnosis and management
Creators: name: Panizza, Pedro
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Venous access
subject: Technical aspects
subject: Arterial access
subject: Ultrasound
subject: MR-Angiography
subject: CT-Angiography
subject: Vascular
subject: Extremities
subject: Arteries / Aorta
subject: Dissection

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Review de anatomy of the inguinal region. 2. Analyze the favorable and unfavorable points related to the imaging methods used in the evaluation of complications after a femoral vascular access. 3. Illustrate cases with minor and major...
Modified Linear Programming and Class 0 Bounds for Graph Pebbling
Creators: name: Cranston, Daniel W.
name: Postle, Luke
name: Xue, Chenxiao
name: Yerger, Carl
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Given a configuration of pebbles on the vertices of a connected graph $G$, a \emph{pebbling move} removes two pebbles from some vertex and places one pebble on an adjacent vertex. The \emph{pebbling number} of a graph $G$ is the smallest integer $k$ such that for each vertex $v$ and each configuration of $k$ pebbles on $G$ there is a sequence of pebbling moves that places at least one pebble on $v$. First, we improve on results of Hurlbert, who introduced a linear optimization technique for graph pebbling. In particular, we use a different set of weight functions, based on graphs more general than trees. We apply this new idea to some graphs from Hurlbert's paper to give improved bounds on their pebbling numbers. Second, we investigate the structure of Class 0 graphs with few edges. We show that every $n$-vertex Class 0 graph has at least $\frac53n - \frac{11}3$ edges. This disproves a conjecture of Blasiak et al. For diameter 2 graphs, we strengthen this lower bound to $2n - 5$, which is best possible. Further, we characterize the graphs where the bound holds with equality and extend the argument to obtain an identical bound for diameter 2 graphs with no cut-vertex.
description: 19 pages, 8 figures
Schools, Schooling, and Children's Support of Their Aging Parents
Creators: name: Brauner-Otto, Sarah R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Intergenerational transfers play an important role in individuals' lives across the life course. In this paper I pull together theories on intergenerational transfers and social change to inform our understanding of how changes in the educational context influence children's support of their parents. By examining multiple aspects of a couple's educational context, including husbands' and wives' education and exposure to schools, this paper provides new information on the mechanisms through which changes in social context influence children's support of their parents. Using data from a rural Nepalese area I use multilevel logistic regression to estimate the relationship between schooling, exposure to schools, and the likelihood of couples giving to their parents. I find that both schooling and exposure to schools itself have separate, opposite effects on support of aging parents. Higher levels of schooling for husbands was associated with a higher likelihood of having given support to husbands' parents. On the other hand, increased exposure to schools for husbands and wives was associated with a lower likelihood of having given to wives' parents. Findings constitute evidence that multiple motivations for intergenerational support exist simultaneously and are related to social context through different mechanisms.
(101128) George Hugh Kidd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Parenting and child externalizing behaviors: Are the associations specific or diffuse?
Creators: name: Rakow, Aaron
name: McKee, Laura
name: Forehand, Rex
name: Colletti, Christina
name: Jones, Deborah J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Building upon the link between inadequate parenting and child noncompliance, aggression, and oppositionality, behavioral parent training has been identified as a well-established treatment for externalizing problems in children. Much less empirical attention has been devoted to examining whether inadequate parenting and, in turn, behavioral parent training programs, have specific effects on child externalizing problems or more diffuse effects on both internalizing and externalizing problems. As an initial attempt to examine the specificity of parenting and childhood externalizing problems, this review examines prior research on the association of three parenting behaviors (parental warmth, hostility, and control) with child externalizing versus internalizing problems. Notably, findings revealed relatively little evidence for the specificity of parenting and child externalizing behaviors in the general parenting literature or in the family context of parent depression. Clinical implications and directions for future research are discussed.
Personality Assessment Inventory internalizing and externalizing structure in veterans with posttraumatic stress disorder: Associations with aggression: PTSD and Aggression
Creators: name: Elbogen, Eric B.
name: Beckham, Jean C.
name: Dennis, Paul A.
name: Hertzberg, Michael A.
name: Clancy, Carolina P.
name: Calhoun, Patrick S.
name: Van Voorhees, Elizabeth E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Posttraumatic stress disorder (PTSD) is associated with aggressive behavior in veterans, and difficulty controlling aggressive urges has been identified as a primary postdeployment readjustment concern. Yet only a fraction of veterans with PTSD commit violent acts. The goals of this study were to (1) examine the higher-order factor structure of Personality Assessment Inventory (PAI) scales in a sample of U.S. military veterans seeking treatment for PTSD; and (2) to evaluate the incremental validity of higher-order latent factors of the PAI over PTSD symptom severity in modeling aggression. The study sample included male U.S. Vietnam (n = 433) and Iraq/Afghanistan (n = 165) veterans who were seeking treatment for PTSD at an outpatient Veterans Affairs (VA) clinic. Measures included the Clinician Administered PTSD Scale, the PAI, and the Conflict Tactics Scale. The sample was randomly split into two equal subsamples (n’s = 299) to allow for cross-validation of statistically derived factors. Parallel analysis, variable clustering analysis, and confirmatory factor analyses were used to evaluate the factor structure, and regression was used to examine the association of factor scores with self-reports of aggression over the past year. Three factors were identified: internalizing, externalizing, and substance abuse. Externalizing explained unique variance in aggression beyond PTSD symptom severity and demographic factors, while internalizing and substance abuse did not. Service era was unrelated to reports of aggression. The constructs of internalizing versus externalizing dimensions of PTSD may have utility in identifying characteristics of combat veterans in the greatest need of treatment to help manage aggressive urges.
Caregiving, residence, race, and depressive symptoms
Creators: name: Williams, Redford B.
name: Dilworth-Anderson, Peggye
name: Siegler, Ilene C.
name: Haney, Thomas L.
name: Brummett, Beverly H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The objective of this study is to evaluate the psychological responses to caregiving between black and white dementia caregivers measured by self-reports of depressive symptoms evaluating the impact of sub-components of the Center for Epidemiologic Studies Depression Scale (CES-D) and residential arrangements of the caregiving dyad. The method included 87 intergenerational family caregivers enrolled in the Duke Caregiver Study (50 white and 37 black). Total CES-D and the four sub-components were modeled as dependent measures in separate linear regressions. Three models were examined. The first model tested race, living arrangements, and their interaction. The second model adjusted for age, gender, education, income, health status, cultural justification for caregiving, crime concerns, systolic blood pressure, diastolic blood pressure, and glycosylated hemoglobin. A third model added adjustment for caregiver burden. The results showed that there was a significant race by residence interaction for CES-D, somatic symptoms and depressive affect such that when the dyads are living apart – with the care recipient in their own home or in an institutional setting – whites reported more depressive symptoms than blacks. When the dyads lived together, this was reversed, and blacks reported higher depressive symptoms than whites. To conclude, all the parameters such as race, living arrangements, and the components of depression need to be taken into account to understand the impact of caregiving on the emotional health of caregivers.
title: How good is ultrasound at assessing axillary nodal disease in patients with breast cancer?
Creators: name: Sudderuddin, Siham
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Cancer
subject: Staging
subject: Sampling
subject: Ultrasound
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: PURPOSE: To retrospectively assess the efficacy of axillary ultrasound and fine needle aspiration (FNA) in staging the axilla of patients with breast cancer by correlating the recorded radiological outcome at the time of diagnosis with the...
(101123) Sydney Paul Ham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Imaging Features of Intracranial Meningiomas with Histopathological Correlation
Creators: name: Manzella, Adonis
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Diagnostic procedure
subject: MR
subject: CT
subject: Oncology
subject: Neuroradiology brain
subject: CNS
subject: Surgery
subject: Neoplasia
subject: Pathology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Meningiomas are the most commom primary intracranial tumors, with an incidence of 13%–26% [1]. They arise from arachnoidal cap cells, commonly occurring on the brain surface. Rarely, they are seen in the brain ventricles.Many cases of meningiomas...
Impact papers on aging in 2009
Creators: name: Verdin, Eric
name: Vijg, Jan
name: Longo, Valter
name: Serrano, Manuel
name: Bonner, William M.
name: Gorospe, Myriam
name: Bohr, Vilhelm A.
name: Sinclair, David A.
name: Kenyon, Cynthia
name: Finch, Caleb E.
name: DePinho, Ronald A.
name: Hall, Michael N.
name: Tower, John
name: Osiewacz, Heinz D.
name: Brosh, Robert M.
name: Tilly, Jonathan L.
name: Hekimi, Siegfried
name: Rando, Thomas A.
name: Helfand, Stephen L.
name: Nussenzweig, Andre
name: Bartke, Andrzej
name: Skulachev, Vladimir P.
name: Gudkov, Andrei V.
name: Kroemer, Guido
name: Campisi, Judy
name: Donehower, Lawrence A.
name: Karlseder, Jan
name: Blasco, Maria A.
name: Brunet, Anne
name: Finkel, Toren
name: Peeper, Daniel S.
name: Sharpless, Norman E.
name: Rudolph, K. Lenhard
name: Blagosklonny, Mikhail V.
name: Sassone-Corsi, Paolo
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The editorial board of Aging reviews research papers published in 2009, which they believe have or will have a significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacologic interventions into aging. The emerging message in 2009 is that aging is not random but determined by a genetically-regulated longevity network and can be decelerated both genetically and pharmacologically.
Supramolecular coordination cages based on light-switchable diarylethene ligands
Creators: name: Li, Rujin
Publisher: name: Technische Universität Dortmund
Year: 2019
Subjects: subject: Coordination cage
subject: Diarylethene
subject: Light-switchable
subject: Photochemistry
subject: 540
subject: Koordinationschemie
subject: Photochemie

description: Supramolecular coordination cages, assembled from square-planer cations (PdII or PtII) and banana-shaped ligands, have been widely studied in the past decades. Interests in this field gradually shifted from structure to function. This thesis explores the self-assembly of light-switchable homo- and hetero-leptic cages formed by Diarylethene (DAE) ligands which enable a fast photo-responsive interconversion between a flexible open form and rigid closed form of the chromophore backbone. In addition, the host-guest chemistry, their application in photo-controlled chirality transfer and singlet oxygen generation are investigated.
MPEC 2023-T203 : 2023 TE8
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 TE8

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Sharp Pointwise Weyl Laws for Schrödinger Operators with Singular Potentials on Flat Tori
Creators: name: Huang, Xiaoqi
name: Zhang, Cheng
Publisher: name: arXiv
Year: 2021
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: Classical Analysis and ODEs (math.CA)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 58J50, 35P15

description: The Weyl law of the Laplacian on the flat torus $\mathbb{T}^n$ is concerning the number of eigenvalues $\leλ^2$, which is equivalent to counting the lattice points inside the ball of radius $λ$ in $\mathbb{R}^n$. The leading term in the Weyl law is $c_nλ^n$, while the sharp error term $O(λ^{n-2})$ is only known in dimension $n\ge5$. Determining the sharp error term in lower dimensions is a famous open problem (e.g. Gauss circle problem). In this paper, we show that under a type of singular perturbations one can obtain the pointwise Weyl law with a sharp error term in any dimensions. Moreover, this result verifies the sharpness of the general theorems for the Schrödinger operators $H_V=-Δ_{g}+V$ in the previous work of the authors, and extends the 3-dimensional results of Frank-Sabin to any dimensions.
description: 58 pages. To appear in Communications in Mathematical Physics
Expression of p16 INK4a in peripheral blood T-cells is a biomarker of human aging
Creators: name: Torrice, Chad
name: Burd, Christin E.
name: Liu, Yan
name: Cho, Hyunsoon
name: Sharpless, Norman E.
name: Thomas, Nancy E.
name: Ibrahim, Joseph G.
name: Sanoff, Hanna K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Expression of the p16INK4a tumor suppressor sharply increases with age in most mammalian tissues, and contributes to an age-induced functional decline of certain self-renewing compartments. These observations have suggested that p16INK4a expression could be a biomarker of mammalian aging. To translate this notion to human use, we determined p16INK4a expression in cellular fractions of human whole blood, and found highest expression in peripheral blood T-lymphocytes (PBTL). We then measured INK4/ARF transcript expression in PBTL from two independent cohorts of healthy humans (170 donors total), and analyzed their relationship with donor characteristics. Expression of p16INK4a, but not other INK4/ARF transcripts, appeared to exponentially increase with donor chronologic age. Importantly, p16INK4a expression did not independently correlate with gender or body-mass index, but was significantly associated with tobacco use and physical inactivity. In addition, p16INK4a expression was associated with plasma interleukin-6 concentration, a marker of human frailty. These data suggest that p16INK4a expression in PBTL is an easily measured, peripheral blood biomarker of molecular age.
Spin-unrestricted random-phase approximation with range separation: Benchmark on atomization energies and reaction barrier heights
Creators: name: Mussard, Bastien
name: Reinhardt, Peter
name: Angyan, Janos
name: Toulouse, Julien
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We consider several spin-unrestricted random-phase approximation (RPA) variants for calculating correlation energies, with and without range separation, and test them on datasets of atomization energies and reaction barrier heights. We show that range separation greatly improves the accuracy of all RPA variants for these properties. Moreover, we show that a RPA variant with exchange, hereafter referred to as RPAx-SO2, first proposed by Sz-abo and Ostlund [A. Szabo and N. S. Ostlund, J. Chem. Phys. 67, 4351 (1977)] in a spin-restricted closed-shell formalism, and extended here to a spin-unrestricted formalism , provides on average the most accurate range-separated RPA variant for atomization energies and reaction barrier heights. Since this range-separated RPAx-SO2 method had already been shown to be among the most accurate range-separated RPA variants for weak intermolecular interactions [J. Toulouse, W. Zhu, A. Savin, G. Jansen, and J. G. {Á}ngy{á}n, J. Chem. Phys. 135, 084119 (2011)], this works confirms range-separated RPAx-SO2 as a promising method for general chemical applications.
Hot topics in stem cells and self-renewal: 2010
Creators: name: Sharpless, Norman E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: In many tissues, mammalian aging is associated with a decline in the replicative and functional capacity of somatic stem cells and other self-renewing compartments. Understanding the basis of this decline is a major goal of aging research. In particular, therapeutic approaches to ameliorate or reverse the age-associated loss of stem function could be of use in clinical geriatrics. Such approaches include attempts to protect stem cells from age-promoting damage, to ‘rejuvenate’ stem cells through the use of pharmacologic agents that mitigate aging-induced alterations in signaling, and to replace lost stem cells through regenerative medicine approaches. Some headway has been made in each of these arenas over the last 18 months including advances in the production of donor-specific totipotent stem cells through induced pluripotency (iPS), gains in our understanding of how tumor suppressor signaling is controlled in self-renewing compartments to regulate aging, and further demonstration of extracellular ‘milieu’ factors that perturb stem cell function with age. This period has also been marked by the recent award of the Nobel Prize in Physiology or Medicine for elucidation of telomeres and telomerase, a topic of critical importance to stem cell aging.
Synthesis and biological evaluation of small molecule GLUT inhibitors that cause glucose starvation in cancer
Creators: name: Reckzeh, Elena Sabrina
Publisher: name: Technische Universität Dortmund
Year: 2019
Subjects: subject: Cancer
subject: Warburg effect
subject: GLUT
subject: Small molecule
subject: Glucose uptake
subject: Metabolic plasticity
subject: 570
subject: 540
subject: Zellbiologie
subject: Krebs, Medizin

description: Deregulation of cellular metabolism has been well established as one hallmark of cancer. Increased aerobic glycolysis in cancer cells, termed the Warburg effect, is associated with an overexpression of different glucose transporter isoforms, especially GLUT-1 but also GLUT-3. To date, numerous GLUT inhibitors have been reported to induce cell death in cancer, yet improvement of selectivity and potency as well as unspecific toxicity of such inhibitors remain major challenges. The piperazin-2-one compound class was identified in a cancer cell-based screen to potently inhibit the uptake of 2-deoxyglucose (2-DG). Synthesis and testing of structural analogues revealed a conclusive structure-activity relationship with its most active enantiomerically pure analogue Glutor (GLucose Uptake inhibiTOR) that inhibited 2-DG uptake with a low nanomolar efficacy in a GLUT-1, -2, -3-selective manner. Furthermore, Glutor reduced the growth of a wide range of monolayer cultured cancer cell lines (2D) and in physiologically more relevant context (3D) while leaving non-malignant cells unaffected. An observed upregulation of GLUT-1 and GLUT-3 expression upon glucose starvation indicates the necessity of a GLUT-1/-3 selectivity profile of small molecular GLUT inhibitiors in order to fully restrict cellular glucose uptake over time. Furthermore, the metabolic plasticity of cancer led to an increased sensitivity towards glucose uptake restriction upon simultaneous inhibition of other metabolic pathways such as glutaminolysis via glutaminase inhibitor CB-839 or oxidative phosphorylation via complex I inhibitor Aumitin. Hence, combinatorial treatment approaches revealed a promising strategy to restrict cancer cell growth more efficiently. Most results obtained in this thesis with Glutor could be confirmed as universal for small molecule glucose uptake inhibitors, irrespectively of their GLUT isoform selectivity.
(101124) Edith Margaret Ham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Swapping in lattice-based cell migration models
Creators: name: Noureen, Shahzeb Raja
name: Owen, Jennifer P.
name: Mort, Richard L.
name: Yates, Christian A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cell Behavior (q-bio.CB)
subject: FOS: Biological sciences

description: Cell migration is frequently modelled using on-lattice agent-based models (ABMs) that employ the excluded volume interaction. However, cells are also capable of exhibiting more complex cell-cell interactions, such as adhesion, repulsion, pulling, pushing and swapping. Although the first four of these have already been incorporated into mathematical models for cell migration, swapping has not been well studied in this context. In this paper, we develop an ABM for cell movement in which an active agent can 'swap' its position with another agent in its neighbourhood with a given swapping probability. We consider a two-species system for which we derive the corresponding macroscopic model and compare it with the average behaviour of the ABM. We see good agreement between the ABM and the macroscopic density. We also analyse the movement of agents at an individual level in the single-species as well as two-species scenarios to quantify the effects of swapping on an agent's motility.
title: Renal cystic lesions: Multi-technique approach
Creators: name: Lucena González, Maria Jesús
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Cysts
subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: CT
subject: Management
subject: Kidney

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To differentiate between focal and multifocal renal cystic disease, understanding the physiopathology and imaging features of each entity. To describe ultrasound (US) and computed tomography (CT) findings of cystic renal lesions. To review the...
(101125) Gertrude M Ham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.