cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The role and regulation of an actomyosin complex in membrane remodeling during regulated exocytosis in a live rodent model system
Creators: name: Milberg, Oleg
Publisher: name: No Publisher Supplied
Year: 2015

description: Our lab has developed a subcellular imaging technique based on intravital microscopy (IVM) to study the highly conserved process of regulated exocytosis, as it occurs in live rodents, using the submandibular salivary glands (SSGs) as a model system for exocrine secretion. Previous work, mainly done on rats and commercially available transgenic and wild-type mice, determined that an actomyosin complex, composed of F-actin and nonmuscle myosin II (NMII) isoforms A and B (NMIIA and NMIIB, respectively), forms around single secretory granules that have fused with the apical plasma membrane (APM) following β-adrenergic stimulation of regulated exocytosis. This complex is required to promote the full integration of the granules into the APM, and although the role of F-actin in regulating granule integration was established, the roles and regulation of NMIIA and NMIIB in this process were not determined, and therefore, they are the main topics discussed in this thesis.       To this end, a series of tools, which includes 1) NMII floxed mice, 2) transgenic and knock-in mice, 3) transgene delivery and expression by viral and non-viral means, and 4) various pharmacological inhibition approaches, were developed. This thesis work shows that: 1) both NMII isoforms are required for granule integration to occur, with NMIIA regulating the dynamics of the fusion pore and NMIIB stabilizing the granules and providing the necessary force for their gradual integration; 2) both NMII isoforms are recruited onto the granules in an F-actin independent manner and subsequently activated by the phosphorylation of their regulatory light chains by myosin light chain kinase (MLCK); and 3) MLCK is recruited through the GTPase Septin 2, and possibly other members of the septin family (Septins 6, 7 and 9) in an F-actin dependent manner. Live imaging by IVM provided further details on the kinetics and dynamics of actomyosin complex assembly and function, which lead to a mechanistic model of actomyosin activity in membrane remodeling during regulated exocytosis in the SSGs. This work is the first to describe how the actomyosin complex functions in a live rodent during a normal physiological process.
Trichomyia longa Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia longa

description: Trichomyia longa Araújo & Bravo sp. nov.
(Figs. 12A–H)
Diagnosis. Gonocoxites with two elongated arms, one pilose and one bare, both curved; aedeagal complex with two pairs of projections, the dorsal smaller than ventral projection, distally curved to the midline; ejaculatory apodeme short, 1.2 times the length of gonostylus, cercus with apical rod-like bristles.
Description. Male. Head subcircular in frontal view. Antenna with 13 flagellomeres; scape shorter than the subspherical pedicel; flagellomeres pyriform (Fig. 12B); 13th flagellomere subcylindrical with terminal apiculus separated by a suture (Fig. 12C); ascoids paired, 1.4 times the length of flagellomeres (Fig. 12A). Palpus with three segments; 1st segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.7:0.8 (Fig. 12D). Wing. R4+5 incomplete at base; r-m and m-cu absent (Fig. 12E). Male terminalia: Hypandrium fused with gonocoxites. Gonocoxites with two elongated arms, one pilose and one bare, both curved. Gonostylus articulated ventrally to gonocoxite, bare, subrectangular in lateral view (Figs. 12F, 12H). Aedeagal complex with two pairs of projections, the dorsal smaller than ventral; the dorsal projection distally curved to the midline. Aedeagus simple (Fig. 12F). Ejaculatory apodeme short, 1.2 times the length of gonostylus. Epandrium pilose, wider than long. Cercus pilose (Fig. 12G), subelliptical in lateral view with a group of apical, thick bristles. Hypoproct with apical micropilosity (Fig. 12H).
Female. Unknown.
Material examined. Brazil, Bahia, Porto Seguro municipality, Estação Vera Cruz, holotype ♂, 05.XII.2002, F.
Bravo leg. (MZFS); 1 paratype ♂ same locality, date and collector than holotype (MZFS). Etymology. The epithet longa refers to the elongated arms of gonocoxite. Distribution. Brazil—Bahia.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 28-30, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Are abstract words grounded in vertical space?
Creators: name: Calderon, Arturo
Publisher: name: No Publisher Supplied
Year: 2015

description: The literature on embodied cognition poses as a formidable contender to the amodal view of the mind. The last ten years have resulted in a plethora of support for the embodiment/grounding of concrete language processing. However, the issue of abstract concepts has not been resolved. If it is true that abstract concepts are embodied or grounded, how does this coincide with the fact that abstract concepts refer to specific things in space like bodies. Therefore, this issue must be addressed to investigate the extent of the grounding of language processing. The present paper features two studies where participants view a word associated with either upward or downward space, followed by an identification task of a target letter which either matched the associated location of the word or not. It was predicted that spatial targets which match a presented word’s spatial association would result in reaction time interference. The results were found to be inconclusive. Methodological problems and future directions are presented and suggested.
Trichomyia ituberensis Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia ituberensis

description: Trichomyia ituberensis Araújo & Bravo sp. nov.
(Figs. 13A–I)
Diagnosis. Projections in the aedeagal complex complex, a distal pair with a hook-like apex; the proximal pair with three expansions, all shorter than the distal; ejaculatory apodeme short, 1.7 times the length of gonostylus; cercus with apical rod-like bristles.
Description. Male. Head subcircular in frontal view. Antenna with 13 flagellomeres; scape slightly longer than pedicel; pedicel subspherical; basal flagellomeres pyriform (Fig. 13A); 13th flagellomere subcylindrical with terminal apiculus separated by a suture (Fig. 13H); ascoids paired, 1.5 times the length of flagellomeres (Fig. 13G). Palpus with three segments; 1st segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.7:0.9 (Fig. 13B). Wing. R4+5 articulated at R3; r-m present; m-cu absent (Fig. 13C). Male terminalia: Hypandrium fused with gonocoxites. Arm of gonocoxites curved in lateral view (Fig. 13E) and convergent in dorsal view (Fig. 13F) with some apical, rod-like bristles. Gonostylus articulated ventrally to gonocoxite, bare. Projections in the aedeagal complex complex, a distal pair with a hook-like apex; the proximal pair with three expansions, all shorter than the distal. Aedeagus bifid, ending at the same level of distal projection of aedeagal complex (Fig. 13F). Ejaculatory apodeme short, 1.7 times the length of gonostylus. Epandrium wider than long (Fig. 13I). Cercus pilose, apex narrower than base in lateral view with four apical, elongated and rod-like bristles (Fig. 13D).
Female. Unknown.
Material examined. Brazil, Bahia, Ituberá municipality, 12.VI.2002, holotype ♂, F. Bravo leg. (MZFS).
Etymology. The epithet ituberensi s is allusive to the type locality for this species.
Distribution. Brazil—Bahia.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on page 30, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Who are you?
Creators: name: Gomez, Louis
Publisher: name: No Publisher Supplied
Year: 2015

description: The use of self is a prime skill in clinical social work practice. Clinical case management is a part of clinical practice, yet for various reasons it is deemed less clinical by mental health professionals who are less experienced or by MSW graduate students. Drawing from professional literature and my own professional experiences, I will demonstrate how use of self in clinical case management allows me the opportunity to have positive outcomes with clients, despite  bureaucratic challenges.
Say on pay
Creators: name: Mason, Stephania
Publisher: name: No Publisher Supplied
Year: 2015

description: For the last two decades there has been quite a bit of debate about whether executives receive excessive compensation and if so, how to control it. A number of countries have instituted some type of Say on Pay rules, affording shareholders the right to vote on executive compensation. Much of this regulatory activity and debate is predicated on the notion that shareholder voting actually influences executive compensation for the better. Although Say on Pay continues to grow as a regulatory tool, the effectiveness of it as a mechanism to effect change remains an open and controversial question, and academic research has been inconclusive. Some prior studies find no change in the level of CEO pay around the adoption of Say on Pay in the U.S. and the U.K. (e.g., see Ferri & Maber (2013) for the U.K. and Iliev & Vitanova (2013) for the U.S.), whereas other studies provide strong evidence that Say on Pay is associated with lower CEO pay. (e.g., see Correa & Lel (2013)). The primary purpose of this dissertation is to investigate the impact of Say on Pay by addressing an important question: Do firms alter executive compensation after the enactment of Say on Pay? I conduct a meta-analysis on the impact of Say on Pay on executive compensation, comprising prior tests derived from 29 primary studies. Impact is measured for the firm by comparing the level of executive compensation and its growth rate; pay-performance sensitivity; pay dispersion (between the CEO and other top executives); and composition of executive compensation in the pre- and post-Say on Pay periods. I find that Say on Pay does not reduce executive compensation; however it does change the composition of the compensation. These results are inconsistent with the public interest theory of regulation, which posits that regulation is implemented to improve some public good (reduce executive compensation). In addition, I construct an international comparative analysis of Say on Pay votes outlining the history of compensation, political trends, and corporate governance characteristics that led to the specific legislation in each jurisdiction in order to evaluate the impact of Say on Pay by type and find that binding votes lead to larger CEO compensation reduction.
Scope of comparative quantifiers
Creators: name: Oho, Atsushi
Publisher: name: No Publisher Supplied
Year: 2015

description: This thesis examines the scope taking property of comparative quantifier phrases (CQPs) in English. It has been widely acknowledged that scope of CQPs in non-subject position is frozen at the surface position: CQPs must take narrow scope relative to a subject quantifier. Experimental evidence provided in this thesis, however, suggests that CQPs in non-subject position can take wide scope over a quantifier in subject position. Given the findings, I argue that scope of non-subject CQPs is not absolutely frozen at the surface position and the scope taking property is significantly influenced by contextual factors. The experimental results show that participants are able to access the inverse scope reading when a test sentence is given under a context in which the surface scope interpretation is not compatible with general world knowledge. The results also indicate that the scope taking property of CQPs with respect to a subject quantifier is not different from that of plural numerals, which are assumed to take wide scope over a subject quantifier. The findings raise the possibility that the widely believed scope rigidity of CQPs is governed not by the grammar, but by extragrammatical factors: taking wide scope is strongly disfavored but crucially not ungrammatical. This possibility can be extended to other quantifiers and languages that have shown scope freezing phenomena. I take Japanese, a scope rigid language, as an example and discuss the defreezing effect of the contextual manipulation.
title: Unter Schafen: Wollfett im Textildesign
Creators: name: Rako, Fabienne
Publisher: name: Universtität Kassel
Year: 2023
Subjects: subject: Wolle
subject: Materialdesign
subject: Nachhaltige Produktentwicklung
classificationCode: 700
subject: 700
classificationCode: Produktentwicklung
subject: Produktentwicklung
classificationCode: Nachhaltigkeit
subject: Nachhaltigkeit
classificationCode: Lanolin
subject: Lanolin
classificationCode: Textilien
subject: Textilien
classificationCode: Design
subject: Design
classificationCode: Wollverarbeitung
subject: Wollverarbeitung

description:
Among Sheep’ explores the potential of the natural combination of wool fibres and wool fat in a technical, health-promoting textile. The material development 'FatPad' deals with the design of possible applications of a greasy wool felt in the treatment of inflamed skin.

Due to globalized production processes, european wool and its wool fat have become unused waste materials that are produced annually. Recent design developments are mainly dealing with utilizing the wool fibers. The primary research question of the thesis is whether wool grease has health-promoting potential in the field of textile and product design and to assess potential applications for raw wool fat in design. The 'FatPad' is a greasy material made from the natural combination of wool fibers and wool fat. It promotes skin regeneration and protects the skin from drying out. The fat-fiber composite is applied as an insert in products with direct skin contact and aims to assist in the treatment of skin irritations and mild-moderate eczema.
The industrially and seamlessly knitted sleeve is designed to meet the needs of atopic dermatitis patients and serves as scratch protection. The FatPad is located at the crook of the elbow, and with consistent, gentle pressure, the itching subsides
Permalife Of The Archive: Archaeogaming As Queergaming
Creators: name: Nicholls, Florence Smith
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Archaeogaming and queer games studies have both grown as paradigms in the last decade. The former broadly refers to the archaeological study of games, while the later concerns the application of queer theory to the medium. To date, there has been limited engagement of archaeogamers with queer games scholarship, and vice versa. This article argues that there are epistomological parallels between the two; as they are both concerned with the limits and ethics of representation, the personal and political contexts of game development and engagement with video games through transgressive play.
 The paper is structured around an extended literature review and three vignettes that reflect on the author's personal experience of conducting archaeogaming research, an ethnographic study of Wurm Online, an archaeological survey of Elden Ring and a player study of the generative archaeology game Nothing Beside Remains. While archaeogaming can learn from the centring of subjective lived experience and labour in the queer games sphere, archaeogaming as a form of game preservation can also benefit queer games studies.
description: 9 pages
Additional file 8: Table S5. of Fangorn Forest (F2): a machine learning approach to classify genes and genera in the family Geminiviridae
Creators: name: JosĂŠ Silva
name: Thales Carvalho
name: Fontes, Elizabeth
name: Cerqueira, Fabio
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Performance results of the tests (performed with the Weka) for the models of family, genus and gene classification. (DOC 147 kb)
Trichomyia acanthostylis Quate
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia acanthostylis

description: Trichomyia acanthostylis Quate
Trichomyia acanthostylis Quate, 1996: 11 –12, figs. 3e–h.
Comments. Males of T. acanthostylis are recognized by the filiform gonostylus with spiniform bristles; elongated arm of gonocoxite with apical bristles; ejaculatory apodeme long, 2.5 times the length of gonostylus.
Material examined. The type specimens were not examined; however, the description and figures of Quate (1996) allowed for the identification of the specimens.
Material examined. Costa Rica, Heredia, Puerto Viejo de Sarapaque, Est. Biol. La Selva, 1 ♂, 01.VII.1993, without name of colector (MZFS).
Distribution. Costa Rica.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on page 30, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Trichomyia annae Bravo
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia annae

description: Trichomyia annae Bravo
Trichomyia annae Bravo, 2001c: 123 –125, figs. 9–17.
Comments. Males of T. annae are recognized by the two pairs of arm of gonocoxites, one in each pair longer than the other, with rounded apex and thick bristle, the other relatively narrow, with elongated bristles on its surface; ejaculatory apodeme long, 5.0 times the length of gonostylus.
Material examined. Brazil, Bahia: Serra da Jibóia, holotype ♂, 16.VI.2000, F. Bravo leg. (MZFS); 1 paratype ♂, same locality, and collector than holotype, 14.III.2001 (MZFS).
Distribution. Brazil—Bahia.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 30-32, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Additional file 1: Figure S1. of Molecular detection of Leishmania infantum and Leishmania tropica in rodent species from endemic cutaneous leishmaniasis areas in Morocco
Creators: name: Echchakery, Mohamed
name: Chicharro, Carmen
name: Boussaa, Samia
name: Nieto, Javier
name: Carrillo, Eugenia
name: Ortega Sheila
name: Moreno, Javier
name: Boumezzough, Ali
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology
subject: 60506 Virology

description: Profile of agarose (1.5%) gel for diagnostic of Leishmania spp. in DNA extracted from tissue from rodent species, using LnPCR for to amplify part of the SSU rRNA gene for diagnosis. Lane MM: 100 bp molecular marker (DNA ladder); Lanes 1, 12: negative controls (no DNA PCR); Lane 13: positive control (MHOM/FR/78/LEM75); Lanes 2–11: DNA extracted of tissue from rodent species. LnPCR for first amplification was carried out using R221/R332 primers. Figure S2. Profile of agarose (1.5%) gel for diagnostic of Leishmania spp. in DNA extracted from tissue from rodent species, using LnPCR for to amplify part of the SSU rRNA gene for diagnosis. Lane MM: 100 bp molecular marker (DNA ladder); Lanes 1, 12, 14: negative controls (no DNA PCR); Lanes 13, 15: positive controls (MHOM/FR/78/LEM75); Lanes 2–11: DNA extracted of tissue from rodent species. LnPCR for second amplification was carried out using R233/R333 primers. Figure S3. Profile of agarose (1.5%) gel for characterization of Leishmania species in DNA extracted from tissue from rodent species, using ITS1-PCR for to amplify the ribosomal internal transcribed spacer 1 (ITS1) region. Lane MM: 100 bp molecular marker (DNA ladder); Lanes 1, 16, 18: negative controls (no DNA PCR); Lanes 17, 19: positive controls (MHOM/FR/78/LEM75); Lanes 2–15: DNA extracted of tissue from rodent species. ITS1-PCR for second amplification was carried out using SAC/VAN2 primers. (DOCX 314 kb)
Additional file 1: Figure S1. of Molecular detection of Leishmania infantum and Leishmania tropica in rodent species from endemic cutaneous leishmaniasis areas in Morocco
Creators: name: Echchakery, Mohamed
name: Chicharro, Carmen
name: Boussaa, Samia
name: Nieto, Javier
name: Carrillo, Eugenia
name: Ortega Sheila
name: Moreno, Javier
name: Boumezzough, Ali
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology
subject: Virology

description: Profile of agarose (1.5%) gel for diagnostic of Leishmania spp. in DNA extracted from tissue from rodent species, using LnPCR for to amplify part of the SSU rRNA gene for diagnosis. Lane MM: 100 bp molecular marker (DNA ladder); Lanes 1, 12: negative controls (no DNA PCR); Lane 13: positive control (MHOM/FR/78/LEM75); Lanes 2–11: DNA extracted of tissue from rodent species. LnPCR for first amplification was carried out using R221/R332 primers. Figure S2. Profile of agarose (1.5%) gel for diagnostic of Leishmania spp. in DNA extracted from tissue from rodent species, using LnPCR for to amplify part of the SSU rRNA gene for diagnosis. Lane MM: 100 bp molecular marker (DNA ladder); Lanes 1, 12, 14: negative controls (no DNA PCR); Lanes 13, 15: positive controls (MHOM/FR/78/LEM75); Lanes 2–11: DNA extracted of tissue from rodent species. LnPCR for second amplification was carried out using R233/R333 primers. Figure S3. Profile of agarose (1.5%) gel for characterization of Leishmania species in DNA extracted from tissue from rodent species, using ITS1-PCR for to amplify the ribosomal internal transcribed spacer 1 (ITS1) region. Lane MM: 100 bp molecular marker (DNA ladder); Lanes 1, 16, 18: negative controls (no DNA PCR); Lanes 17, 19: positive controls (MHOM/FR/78/LEM75); Lanes 2–15: DNA extracted of tissue from rodent species. ITS1-PCR for second amplification was carried out using SAC/VAN2 primers. (DOCX 314 kb)
title: Numerical modelling of hydrogen leakages in confined spaces for domestic applications
Creators: name: Thawani, Bonny
Publisher: name: Cranfield University Defence and Security
Year: 2024
Subjects: subject: Hydrogen
subject: Energy
subject: Security
subject: Modelling and Simulation
subject: Gas Leak

description: This paper is published as: Thawani B, Hazael R, Critchley R. (2024) Numerical modelling of hydrogen leakages in confined spaces for domestic applications. International Journal of Hydrogen Energy, Volume 56, February 2024, pp.797-806 https://doi.org/10.1016/j.ijhydene.2023.12.279
Trichomyia aquita Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia aquita

description: Trichomyia aquita Araújo & Bravo sp. nov.
(Figs. 14A–G)
Diagnosis. Hypandrium and gonocoxites fused, with a basal expansion curved, directed medially; arm of gonocoxite directed dorsally with elongated bristles; two pairs of sclerotized projections in the aedeagal complex; the lateral digitiform, about the same length as the inner, the inner fused, cup-shaped; ejaculatory apodeme 3.0 times the length of gonostylus.
Description. Male. Head subcircular in frontal view. Antenna incomplete in the studied specimens; scape and pedicel subcylindrical; basal flagellomere pyriform and eccentric (Fig. 14A); ascoids 1.3 times as long as the length of flagellomere (Fig. 14B). Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.5:0.6 (Fig. 14C). Wing. Base of R s unsclerotized; r-m and m-cu absent (14D). Male terminalia: Hypandrium and gonocoxites fused with a basal expansion, curved and medially directed. Arm of gonocoxite directed dorsally with elongated bristles (Fig. 14E); gonostylus slightly sclerotized, articulated ventrally to gonocoxite, subtriangular, bare with rounded apex. Aedeagal complex with two pairs of sclerotized projections; the lateral digitiform, about the same length as the inner, the inner fused, cup-shaped. Aedeagus simple (Fig. 14G). Ejaculatory apodeme 3.0 times the length of gonostylus. Epandrium longer than wide. Cercus pilose and piriform. Hypoproct with apical micropilosity (Fig. 14F).
Female. Unknown.
Material examined. Brazil, Amazonas, Presidente Figueiredo, Pitinga, 04.XII.1998, holotype ♂, RQ, LMC leg. (MZFS) 4 paratypes: 2 ♂, same locality, date and colectors as holotype, (MZFS); 2 ♂, same locality as holotype, 15.XIII.1998, RR, LMS leg. (INPA)
Etymology. From tupi-guarani aquitã = short, refers to the length of the arm of gonocoxite.
Distribution. Brazil—Amazonas.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 32-33, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Quantum key distribution with displaced thermal states
Creators: name: Walton, Adam
name: Ghesquière, Anne
name: Varcoe, Benjamin
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Secret key exchange relies on the creation of correlated signals, serving as the raw resource for secure communication. Thermal states, exhibit Hanbury Brown and Twiss correlations, which offer a promising avenue for generating such signals. In this paper, we present an experimental implementation of a central broadcast thermal state quantum key distribution (QKD) protocol in the microwave region. Our objective is to showcase a straightforward method of QKD utilizing readily available broadcasting equipment. Unlike conventional approaches to thermal state QKD, we leverage displaced thermal states. These states enable us to share the output of a thermal source among Alice, Bob, and Eve via both waveguide channels and free space. Through measurement and conversion into bit strings, our protocol produces key-ready bit strings without the need for specialized equipment. By harnessing the inherent noise in thermal broadcasts, our setup facilitates the recovery of distinct bit strings by all parties involved.
description: 18 pages, 10 figures
title: Autonomy is the answer; what was the question?
Creators: name: Spayne, Peter
name: Lacey, Laura J.
name: Cahillane, Marie
name: Saddington, Alistair J.
Publisher: name: Cranfield University Defence and Security
Year: 2024
Subjects: subject: LAWS
subject: AI
subject: Risk Management
subject: Assurance
subject: Safety
subject: Autonomous

description: This paper was also presented at: The International Naval Engineering Conference (INEC), 5-7 November 2024, Liverpool, England The full paper is available at: https://dspace.lib.cranfield.ac.uk/handle/1826/23196
Additional file 1: of A study protocol of the effectiveness of PEGASUS: a multi-centred study comparing an intervention to promote shared decision making about breast reconstruction with treatment as usual
Creators: name: Harcourt, Diana
name: Paraskeva, Nicole
name: White, Paul
name: Powell, Jane
name: Clarke, Alex
Publisher: name: Figshare
Year: 2017
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Flow chart of the PEGASUS trial. (DOCX 43 kb)
Additional file 1: Figures S1  of Avocado fruit maturation and ripening: dynamics of aliphatic acetogenins and lipidomic profiles from mesocarp, idioblasts and seed
Creators: name: Rodríguez-López, Carlos
name: Hernández-Brenes, Carmen
name: Treviño, Víctor
name: Garza, Rocío Díaz De La
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Computational Biology

description: to S10; Table S1 to S4. This file contains a schematic explaining the terminology used in the article to refer to developmental stages (Additional file 1: Figure S1); information regarding acetogenin contents in mesocarp and seed of ‘Hass’ avocado fruit in a fresh weight basis (Additional file 1: Figure. S2, Tables 1 and 2); and micrographies of dyed idioblasts (Additional file 1: Figure S3), results from the assessment of extract purity (Additional file 1: Figure S4, Table S3), and acetogenin contents (Additional file 1: Table S4). Also, it contains complementary information on the metabolomics analysis, such as PCA of the mesocarp features (Additional file 1: Figure S5) and score plots of the mesocarp (Additional file 1: Figure S6) and idioblast (Additional file 1: Figure S7) samples. The corresponding part in seed tissue (Additional file 1: Figure S8) is included, along with the heatmaps of the manually curated TAGs, DAGs, and Acetogenins data (Additional file 1: Figure S9). Finally it contains an example of the grouping algorithm mentioned in the Methods section (Additional file 1: Figure S10). (DOCX 4325 kb)
title: Therapeutic glucose responsive dual gene delivery system for diabetic wound healing
Creators: name: Morey, Mangesh
Publisher: name: University of Galway
Year: 2025
Subjects: subject: Diabetic wounds
subject: gene therapy
subject: glucose responsive gene delivery system
subject: medical devices
subject: Engineering and Informatics

description: Diabetic wound is a severe and multifactorial pathology that results from hyperglycemia. Despite intensive treatment regimes, there has been limited success in promoting diabetic wound healing. Gene therapy demonstrates significant potential in treating a range of life-threatening diseases and conditions. Employing a glucose responsive gene delivery system as a method of treating diabetic wounds represents an innovative approach. The primary aim of this thesis was to design and fabricate a glucose responsive dual gene delivery system and subsequently evaluate its therapeutic potential in promoting diabetic wound healing in a genetically diabetic mice animal model. The fabricated system comprised two scaffolds: fibrin hollow microcapsules and glucose responsive fibrin hydrogel. The fibrin microcapsules were constructed through layer-by-layer assembly on a CaCO3 template, while the glucose responsive fibrin hydrogel was synthesised by adding glucose oxidase enzyme. Both scaffolds were loaded with two separate reporter genes and topically applied to the wounds of the genetically diabetic db/db mice. The group of animals receiving the glucose responsive treatment displayed increased expression of the reporter genes. Most importantly, the fabricated glucose responsive delivery system exhibited significant therapeutic potential, significantly improving diabetic wound healing after seven days post-surgery. Angiogenesis was enhanced, and inflammation was reduced in the glucose responsive treatment group. A total of 23 proteins were altered in the glucose responsive treatment group compared to the non-treated group. Actinin 2, desmin, and MYBPC1 were the most significantly up-regulated proteins in the glucose responsive treatment group. The increased expression of these proteins in the glucose responsive treatment group was validated through immunohistochemistry analysis. The dual gene delivery system that is responsive to glucose, integrated with fibrin, presents itself as a highly promising therapeutic approach for the purpose of normalising diabetic wound healing. The system's cargo may be complemented in order to achieve the desired outcome.
Additional file 1: Table S1. of Genetic analysis of parathyroid and pancreatic tumors in a patient with multiple endocrine neoplasia type 1 using whole-exome sequencing
Creators: name: Kim, Bo-Young
name: Park, Mi-Hyun
name: Hae-Mi Woo
name: Hye-Yeong Jo
name: Kim, Ji
name: Choi, Hyung
name: Koo, Soo
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Number of somatic variants observed in four tumor types. (DOC 64 kb)
Trichomyia araguaensis Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia araguaensis

description: Trichomyia araguaensis Araújo & Bravo sp. nov.
(Figs. 15A –F)
Diagnosis. R4+5 complete; basal expansions of gonocoxites with rounded tips that cross in the apex, medially directed; arm of gonocoxites expanded in the base, with apicolateral bristles and two apical bristles thicker than the others, stare-like; ejaculatory apodeme about the same length as gonostylus.
Description. Male. Head subcircular in frontal view. Antenna with 13 flagellomeres; scape subcylindrical, pedicel subspherical; flagellomeres pyriform and eccentric; ascoids 2.1 times the length of the flagellomere (Fig. 15A); 13th flagellomere subcylindrical with terminal apiculus separated by suture (Fig. 15C). Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.6:0.6 (Fig. 15B). Wing. R4+5 complete; r-m and m-cu absent (Fig. 15D). Male terminalia: Hypandrium and gonocoxites fused with basal expansion with rounded tips that cross in the apex, medially directed. Arm of gonocoxites expanded in the base, with apicolateral bristles and two apical bristles thicker than the others, stare-like. Gonostylus slightly sclerotized, articulated dorsally to gonocoxite, bare and subtriangular. Presence of one pair of subtriangular projections in the aedeagal complex, convergent apically. Aedeagus ending at midlle of projections in the aedeagal complex (Fig. 15 F). Ejaculatory apodeme about as long as gonostylus. Epandrium lost in the specimen studied. Cercus elongated and pilose (Fig. 15E).
Female. Unknown.
Material examined. Venezuela, Aragua, 10 Km N El Limon, holotype ♂, 19.IX.1993, L.W. Quate leg. (MZFS)
Etymology. The epithet refersto the type locality.
Distribution. Venezuela—Aragua.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 33-34, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Additional file 1: of Learning from deaths: Parentsâ   Active Role and ENgagement in The review of their Stillbirth/perinatal death (the PARENTS 1 study)
Creators: name: Danya Bakhbakhi
name: Siassakos, Dimitrios
name: Burden, Christy
name: Jones, Ffion
name: Yoward, Freya
name: Redshaw, Maggie
name: Murphy, Samantha
name: Storey, Claire
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: PARENT focus group schedule. (DOCX 16Â kb)
Trichomyia bahiensis Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia bahiensis

description: Trichomyia bahiensis Araújo & Bravo sp. nov.
(Figs. 16A–I)
Diagnosis. Gonocoxite arm lobe-like, upright in lateral view and with few short spinform bristles in the medial surface; gonostylus plate-like; one pair of projections in the aedeagal complex connected/joined by a thin ventral membrane; ejaculatory apodeme short, 0.4 times the length of gonocoxite; cercus with few small spatulate bristles near the apex.
Description. Male. Head subcircular in frontal view. Antenna: scape subcylindrical, pedicel subspherical; flagellum with 13 flagellomeres, 1st to 12th flagellomeres pyriform and eccentric (Fig. 16A); 13th flagellomere subcylindrical with terminal apiculus separated by suture (Fig. 16C); ascoids 1.1 times the length of a flagellomere (Fig. 16B). Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.6:0.7 (Fig. 16D). Wing. R4+5 incomplete at base; r-m and m-cu absent (Fig. 16E). Male terminalia: Hypandrium and gonocoxites fused. Gonocoxites with arm lobe-like, upright in lateral view and with few short spinform bristles in the medial surface (Figs. 16G, 16I). Gonostylus slightly sclerotized, articulated ventrally to gonocoxite, bare, plate-like. Presence of one pair of projections in the aedeagal complex ending at the same level of aedeagus, united by a thin ventral membrane. Aedeagus filiform (Figs. 16G, 16H). Ejaculatory apodeme short, 0.4 times the length of gonocoxite. Epandrium with posterior margin larger than the anterior margin. Cercus ovoid (Figs. 16F, 16H); dorsal surface of cercus with few small spatulate bristles near the apex (Fig. 16H). Hypoproct with apical micropilosity (Fig. 16F).
Female. Unknown.
Material examined. Brazil, Bahia, Ituberá municipality, 12.VI.2002, holotype ♂, F. Bravo leg. (MZFS); 5 paratypes: 3♂, Bahia, Porto Seguro municipality, Estação Vera Cruz, 05.XII.2002, F. Bravo leg. (MZFS); 1 ♂, Bahia, Cachoeira municipality, Fazenda. Villa Rial, 25.IV.2004, F. Bravo leg. (MZFS); 1 ♂, Fazenda Villa Rial, 20.VII.2004, F. Bravo leg. (MZFS).
Etymology. The epithet bahiensis refers to the type locality.
Distribution. Brazil—Bahia.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on page 34, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
A long march for targeted protein degradation in the new era: expanding E3 ligases
Creators: name: Mi, Dazhao
name: Huang, Anxin
name: Song, Jingfeng
name: Chen, Yihua
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: A long march for targeted protein degradation in the new era: expanding E3 ligases
Additional file 2: Table S2. of Decision support systems for incurable non-small cell lung cancer: a systematic review
Creators: name: D. RĂŠvĂŠsz
name: E. Engelhardt
name: J. Tamminga
name: F. Schramel
name: B. Onwuteaka-Philipsen
name: E. Van De Garde
name: E. Steyerberg
name: E. Jansma
name: H. De Vet
name: V. CoupĂŠ
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer

description: Overview and quality assessment of decision support systems for incurable patients with (initial or recurrent) metastatic non-small cell lung cancer. (DOCX 346Â kb)
The irreducible mass of a regular rotating black hole
Creators: name: Carneiro, F. L.
name: Ulhoa, S. C.
name: da Rocha-Neto, J. F.
name: Maluf, J. W.
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This article presents an analysis of regular rotating black hole solutions within the framework of Teleparallel Equivalent to General Relativity (TEGR). The study evaluates the total energy and derives an analytical expression for the irreducible mass of a regular black hole. The results reveal the significance of these regular black holes as approximations of real astrophysical objects. The investigation explores the behavior of the total energy for different surfaces and its value at spatial infinity. Additionally, the article addresses the instability of the inner horizon and examines the inertial acceleration of an observer inside the inner horizon.
description: 23 pages, 6 figures
Trichomyia bifurcata Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia bifurcata

description: Trichomyia bifurcata Araújo & Bravo sp. nov.
(Figs. 18A –G)
Diagnosis. M2 with base unsclerotized; r-m unsclerotized; two basal expansions on gonocoxite, the dorsal side expanded basally, with divergent apex; the ventral side with narrow tip, curved medially; arm of gonocoxite bifurcate with elongated bristles at apex; cercus terminally expanded with two apical setae.
Description. Male. Head subcircular in frontal view. Antenna incomplete in the studied specimens; scape subcylindrical; pedicel subspherical; flagellomeres pyriform and eccentric; ascoids 1.25 times as long as the length of flagellomere (Fig. 18A). Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.5:0.6 (Fig. 18B). Wing. R4+5 with base unsclerotized; M2 with base unsclerotized; r-m unsclerotized and m-cu absent (Fig. 18C). Male terminalia: Hypandrium and gonocoxites fused with two basal expansions, the dorsal side expanded basally, with divergent apex; the ventral side with narrow tip, curved medially (Fig. 18D). Arm of gonocoxite bifurcate with elongated bristles (Fig. 18 G). Gonostylus slightly sclerotized, articulated ventrally to gonocoxite, near to the base, bare, subtriangular (Figs. 18D, 18 G). Presence of one pair of triangular projections in the aedeagal complex. Aedeagus bifid (18G). Ejaculatory apodeme 0.8 times the length of gonostylus. Epandrium subquadrate. Cercus digitiform (Figs. 18E, 18F) with an expansion with two apical setae (Fig. 18E). Hypoproct with apical micropilosity (Fig. 18F).
Female. Unknown.
Material examined. Brazil, Pará, Santarém, Estrada para alter do Chão, Jurupari, Km1315, 25.XI.1998, holotype ♂, RF, RAN, FLS leg. (MZFS); 16 paratypes: 5 ♂, Amazonas, Manacapuru, Cajatuba, km 69/3, 6.X.1998, without name of collector (MZFS); 2 ♂, Amazonas, Presidente Figueiredo, Pitinga, 04.XII.1998, RQ, LMC leg. (INPA); 3 ♂, Amazonas, Manacapuru, Cajatuba, km 69/3, 20.IV.1998, RQ, RN, PE (INPA); 4 ♂, Amazonas, Manacapuru, Cajatuba, km 69/3, 13.X.1998, without name of collector (MZFS); 1♂, Pará, Barbarena, Est. Caripi, Km4, 24.X.1997, without name of collector (INPA); 1♂, Pará, Novo Repartimento, Vic. Bandeirante, Ramal dos Sem Terra, 27.VIII.1998, without name of collector (MZFS).
Etymology. The epithet bifurcata is allusive to the large number of bifurcated structures (arm of gonocoxite, aedeagus)
Distribution. Brazil—Amazonas, Pará.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 37-38, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Eleticinae Wellman 1910
Creators: name: Bologna, Marco A.
name: Amore, Valentina
name: Pitzalis, Monica
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Meloidae

description: Subfamily Eleticinae
This subfamily of Meloidae (Bologna et al. 2008b) is mainly represented in Namibia by the tribe Derideini, genus Iselma. The new genus Namibeletica, a taxon incertae sedis, probably belongs to the tribe Eleticini, which is represented with certainty in Namibia by the genus Eletica Lacordaire, recognized for the first time in this study. Moreover, Bologna (2009) recorded two genera of the tribe Morphozonitini (Mimiselma Bologna, 2009 and Morphozonitis Pic, 1924) from southern Angola (in the Namib Desert and mopane savannah), just close to northern Namibia, which could be found in the extension of the same ecosystems in Namibia.
description: Published as part of Bologna, Marco A., Amore, Valentina & Pitzalis, Monica, 2018, Meloidae of Namibia (Coleoptera): taxonomy and faunistics with biogeographic and ecological notes, pp. 1-141 in Zootaxa 4373 (1) on page 8, DOI: 10.11646/zootaxa.4373.1.1, http://zenodo.org/record/1151722
MOESM1 of The role of endothelial nitric oxide in the anti-restenotic effects of liraglutide in a mouse model of restenosis
Creators: name: Kushima, Hideki
name: Mori, Yusaku
name: Koshibu, Masakazu
name: Munenori Hiromura
name: Kohashi, Kyoko
name: Michishige Terasaki
name: Tomoyasu Fukui
name: Hirano, Tsutomu
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1. Additional figures (Figs. S1â  S4).