cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Metreleptin for acquired diabetes lipodystrophy
Creators: name: Nagayama, Ayako
name: Ashida, Kenji
name: Kanoko Moritaka
name: Hidaka, Mami
name: Gobaru, Mizuki
name: Tanaka, Seiji
name: Hasuzawa, Nao
name: Akasu, Shoko
name: Goto, Yuka
name: Motomura, Seiichi
name: Hara, Kento
name: Munehisa Tsuruta
name: Wada, Nobuhiko
name: Nakayama, Hitomi
name: Tajiri, Yuji
name: Nomura, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
subject: FOS: Clinical medicine
subject: 111502 Clinical Pharmacology and Therapeutics
subject: 110306 Endocrinology
subject: 110107 Metabolic Medicine

description: Supplemental materials
Modeling the Initial Conditions of Interacting Galaxy Pairs Using Identikit
Creators: name: Mortazavi, S. Alireza
name: Lotz, Jennifer M.
name: Barnes, Joshua E.
name: Snyder, Gregory F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We develop and test an automated technique to model the dynamics of interacting galaxy pairs. We use Identikit (Barnes & Hibbard 2009, Barnes 2011) as a tool for modeling and matching the morphology and kinematics of the interacting pairs of equal-mass galaxies. In order to reduce the effect of subjective human judgement, we automate the selection of phase-space regions used to match simulations to data, and we explore how selection of these regions affects the random uncertainties of parameters in the best-fit model. In this work, we use an independent set of GADGET SPH simulations as input data to determine the systematic bias in the measured encounter parameters based on the known initial conditions of these simulations. We test both cold gas and young stellar components in the GADGET simulations to explore the effect of choosing HI vs. H$α$ as the line of sight velocity tracer. We find that we can group the results into tests with good, fair, and poor convergence based on the distribution of parameters of models close to the best-fit model. For tests with good and fair convergence, we rule out large fractions of parameter space and recover merger stage, eccentricity, pericentric distance, viewing angle, and initial disc orientations within 3$σ$ of the correct value. All of tests on prograde-prograde systems have either good or fair convergence. The results of tests on edge-on discs are less biased than face-on tests. Retrograde and polar systems do not converge and may require constraints from regions other than the tidal tails and bridges.
description: 18 pages, 13 figures, 3 Tables, Accepted for publication in MNRAS
The promises and limitations of gender-transformative health programming with men: critical reflections from the field
Creators: name: Dworkin, Shari L.
name: Colvin, Christopher J.
name: Fleming, Paul J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Since the 1994 International Conference on Population and Development, researchers and practitioners have engaged in a series of efforts to shift health programming with men from being gender-neutral to being more gender-sensitive and gender-transformative. Efforts in this latter category have been increasingly utilised, particularly in the last decade, and attempt to transform gender relations to be more equitable in the name of improved health outcomes for both women and men. We begin by assessing the conceptual progression of social science contributions to gender-transformative health programming with men. Next, we briefly assess the empirical evidence from gender-transformative health interventions with men. Finally, we examine some of the challenges and limitations of gender-transformative health programmes and make recommendations for future work in this thriving interdisciplinary area of study.
Obesogenic home food availability, diet, and BMI in Pakistani and White toddlers
Creators: name: Ward, D.S.
name: Stevens, J.
name: Siega-Riz, A.M.
name: LeCroy, M.N.
name: Cai, J.
name: Bryant, M.
name: Albrecht, S.S.
Publisher: name: Blackwell Publishing Ltd
Year: 2021

description: Individuals of South Asian ethnicity have an increased risk for obesity and related diseases. Foods available in the home during the first 1000 days (conception to 24 months old) are an important determinant of diet, yet no study has examined the association of early-life home food availability (HFA) with later diet and obesity risk in South Asian households. We examined whether obesogenic HFA at 18 months of age is associated with dietary intake and body mass index (BMI) at 36 months of age in low-income Pakistani and White households in the United Kingdom. In this prospective birth cohort study (Born in Bradford 1000), follow-up assessments occurred at 18 (n = 1032) and 36 (n = 986) months of age. Variety and quantity of snack foods and sugar-sweetened beverages (SSBs) in the home and consumed were measured using the HFA Inventory Checklist and food frequency questionnaires, respectively. BMI was calculated using measured length/height and weight. Multinomial logistic regression models examined associations between HFA and tertiles of dietary intake, and multivariable linear regression models assessed associations between HFA and BMI. Pakistani households had a greater variety and quantity of snack foods and SSBs available compared with White households. Variety and quantity of snack foods and SSBs in the home at 18 months were positively associated with children's intake of these items at 36 months, but associations between HFA and BMI were null. Reducing obesogenic HFA during the first 1000 days may promote the development of more healthful diets, though this may not be associated with lower obesity risk during toddlerhood.
Cellular Targeting in Autoimmunity
Creators: name: Timoshchenko, Roman G.
name: Serafin, Donald S.
name: Rogers, Jennifer L.
name: Tarrant, Teresa K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Many biologic agents that were first approved for the treatment of malignancies are now being actively investigated and used in a variety of autoimmune diseases such as rheumatoid arthritis (RA), antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, systemic lupus erythematosus (SLE), and Sjogren’s syndrome. The relatively recent advance of selective immune targeting has significantly changed the management of autoimmune disorders, and in part, can be attributed to the progress made in understanding effector cell function and their signaling pathways. In this review, we will discuss the recent FDA approved biologic therapies that directly target immune cells as well as the most promising investigational drugs affecting immune cell function and signaling for the treatment of autoimmune disease.
Loop quantum cosmology of Bianchi IX: Effective dynamics
Creators: name: Corichi, Alejandro
name: Montoya, Edison
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study numerically the solutions to the effective equations of Bianchi IX spacetimes within Loop Quantum Cosmology. We consider Bianchi IX models with and without inverse triad corrections whose matter content is a scalar field without mass. The solutions are classified using the classical observables. We show that both effective theories --with lapse N=V and N=1-- solve the big bang singularity and reproduce the classical dynamics far from the bounce. Moreover, due to the spatial compactness, there is an infinity number of bounces and recollapses. We study the limit of large volume and show that both effective theories reproduce the same dynamics, thus recovering general relativity. We implement a procedure to identify amongst the Bianchi IX solutions, those that behave like k=0,1 FLRW as well as Bianchi I, II, and VII_0 models. The effective solutions exhibit Bianchi I phases with Bianchi II transitions and also Bianchi VII_0 phases, which had not been studied before, at the quantum nor effective level. We comment on the possible implications of these results for a quantum modification to the classical BKL behaviour.
description: This version to be published in the CQG special issue
Additional file 5 of Association between treatment failure and hospitalization after receipt of neutralizing monoclonal antibody treatment for COVID-19 outpatients
Creators: name: Douin, David J.
name: Wogu, Adane F.
name: Beaty, Laurel E.
name: Carlson, Nichole E.
name: Bennett, Tellen D.
name: Aggarwal, Neil R.
name: Mayer, David A.
name: Ong, Toan C.
name: Russell, Seth
name: Steele, Jeffrey
name: Peers, Jennifer L.
name: Molina, Kyle C.
name: Wynia, Matthew K.
name: Ginde, Adit A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: Additional file 5: Table S1. Medications and conditions used to stratify Mild versus Moderate/Severe immunocompromised status.
Pathogenesis of Food Allergy in the Pediatric Patient
Creators: name: Vickery, Brian P.
name: Chin, Stacy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: In the US and other developed countries, food allergy is a growing epidemic in pediatric populations with a substantial impact on health-related quality of life. As such, there are great efforts underway to unravel the mechanisms of oral mucosal tolerance and to better define the factors related to host and allergen exposure that contribute to the aberrant immune response leading to sensitization and clinical food allergy. Although more research is needed to eventually develop targeted treatment and prevention strategies, this review highlights our current understanding of the pathogenesis of IgE-mediated food allergy.
S1 - Supplementary methods and complete statistical analys from The multi-dimensional nature of information drives prioritization of private over social information in ants
Creators: name: Czaczkes, Tomer J.
name: Beckwith, John J.
name: Anna-Lena Horsch
name: Hartig, Florian
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: Methodological details and complete statistical analysis
Autoimmunity in Immunodeficiency
Creators: name: Koontz, Jessica B.
name: Tarrant, Teresa K.
name: Mattox, Daniel
name: Todoric, Krista
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic defects. Paradoxically, a substantial proportion of PID patients develop autoimmune phenomena in addition to having increased susceptibility to infections from their impaired immunity. Although much of our understanding comes from data gathered through experimental models, there are several well-characterized PID that have improved our knowledge of the pathways that drive autoimmunity. The goals of this review will be to discuss these immunodeficiencies and to review the literature with respect to the proposed mechanisms for autoimmunity within each put forth to date.
Gauge-preheating and the end of axion inflation
Creators: name: Adshead, Peter
name: Giblin, John T.
name: Scully, Timothy R.
name: Sfakianakis, Evangelos I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We study the onset of the reheating epoch at the end of axion-driven inflation where the axion is coupled to an Abelian, $U(1)$, gauge field via a Chern-Simons interaction term. We focus primarily on $m^2ϕ^2$ inflation and explore the possibility that preheating can occur for a range of coupling values consistent with recent observations and bounds on the overproduction of primordial black holes. We find that for a wide range of parameters preheating is efficient. In certain cases the inflaton is seen to transfer all its energy to the gauge fields within a few oscillations. In most cases, we find that the gauge fields on sub-horizon scales end preheating in an unpolarized state due to the existence of strong rescattering between the inflaton and gauge-field modes. We also present a preliminary study of an axion monodromy model coupled to $U(1)$ gauge fields, seeing a similarly efficient preheating behavior as well as indications that the coupling strength has an effect on the creation of oscillons.
description: 32 pages, 13 Figures. V3: matches published version
Ground State Degeneracy of Interacting Spinless Fermions
Creators: name: Wei, Zhong-Chao
name: Han, Xing-Jie
name: Xie, Zhi-Yuan
name: Xiang, Tao
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We propose an eigen-operator scheme to study the lattice model of interacting spinless fermions at half filling and show that this model possesses a hidden form of reflection positivity in its Majorana fermion representation. Based on this observation, we prove rigourously that the ground state of this model is either unique or doubly degenerate if the lattice size $N$ is even, and is always doubly degenerate if $N$ is odd. This proof holds in all dimensions with arbitrary lattice structures.
Autoimmune Lymphoproliferative Syndrome: an Update and Review of the Literature
Creators: name: Shah, Shaili
name: Rao, V. Koneti
name: Tarrant, Teresa K.
name: Wu, Eveline
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Autoimmune lymphoproliferative syndrome (ALPS) is characterized by immune dysregulation due to a defect in lymphocyte apoptosis. The clinical manifestations may be noted in multiple family members and include lymphadenopathy, splenomegaly, increased risk of lymphoma and autoimmune disease, which typically involve hematopoietic cell lines manifesting as multilineage cytopenias. Since the disease was first characterized in the early 1990s, there have been many advances in the diagnosis and management of this syndrome. The inherited genetic defect of many ALPS patients has involved (FAS) pathway signaling proteins, but there remain those patients who carry undefined genetic defects. Despite ALPS having historically been considered a primary immune defect presenting in early childhood, adult onset presentation is increasingly becoming recognized, and more so in genetically undefined patients and those with somatic FAS mutations. Thus, future research may identify novel pathways and/or regulatory proteins important in lymphocyte activation and apoptosis.
A community-based, multi-level, multi-setting, multi-component intervention to reduce weight gain among low socioeconomic status Latinx children with overweight or obesity: The Stanford GOALS randomised controlled trial
Creators: name: Weintraub, D.L.
name: McClain, A.
name: Desai, M.
name: Robinson, T.N.
name: Sanders, L.M.
name: Pratt, C.
name: Matheson, D.
name: Truesdale, K.P.
name: Stevens, J.
name: Kapphahn, K.I.
name: Wilson, D.M.
name: Banda, J.A.
name: Haydel, K.F.
name: Haskell, W.L.
Publisher: name: Lancet Publishing Group
Year: 2021

description: Background: There are few long-term studies of interventions to reduce in low socioeconomic status children with overweight or obesity. The Stanford GOALS trial evaluated a 3-year, community-based, multi-level, multi-setting, multi-component (MMM) systems intervention, to reduce weight gain among low socioeconomic status, Latinx children with overweight or obesity. Methods: We did a two-arm, parallel group, randomised, open-label, active placebo-controlled trial with masked assessment over 3 years. Families from low-income, primarily Latinx communities in Northern California, CA, USA, with 7–11-year-old children with overweight or obesity were randomly assigned to a MMM intervention or a Health Education (HE) comparison intervention. The MMM intervention included home environment changes and behavioural counselling, community after school team sports, and reports to primary health-care providers. The primary outcome was child BMI trajectory over three years. Secondary outcomes included one- and two-year changes in BMI. This trial is registered with ClinicalTrials.gov NCT01642836. Findings: Between July 13, 2012, and Oct 3, 2013, 241 families were recruited and randomly assigned to MMM (n=120) or HE (n=121). Children's mean age was 9·5 (SD 1·4) years, 134 (56%) were female and 107 (44%) were male, and 236 (98%) were Latinx. 238 (99%) children participated in year 1, 233 (97%) in year 2, and 227 (94%) in year 3 of follow-up assessments. In intention-to-treat analysis, over 3 years, the difference between intervention groups in BMI trajectory was not significant (mean adjusted difference −0·25 [95% CI −0·90 to 0·40] kg/m2; Cohen's d=0.10; p=0·45). Children in the MMM intervention group gained less BMI over 1 year than did children in the HE intervention group (−0·73 [–1·07 to −0·39] kg/m2, d=0.55); the same was true over 2 years (−0·63 [–1·13 to −0·14] kg/m2; d =0.33). No differential adverse events were observed. Interpretation: The MMM intervention did not reduce BMI gain versus HE over 3 years but the effects over 1 and 2 years in this rigorous trial show the promise of this systems intervention approach for reducing weight gain and cardiometabolic risk factors in low socioeconomic status communities. Funding: US National Institutes of Health.
On the Names of Livorno in the Hebrew Arabic-Speaking World
Creators: name: Nissan, Ephraim
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

Whereas the Tunisian Arabic name for people from Livorno (Leghorn) has received attention in the scholarly literature, the same cannot be said for the Baghdadi Judaeo-Arabic name of Livorno. The latter subject is the original and necessary contribution of this article: the Maghreb is not Western Asia. In order to more fully appreciate how the Baghdadi Jewish name for Livorno came into being, the history of the export of Jewish books from Livorno is central. Jewish devotional literature published in Livorno (sometimes specifically for the Iraqi market) or emulating the model of Jewish books from Livorno had a steady market in Baghdad, it could be said almost up to the traumatic exodus of the Jews of Iraq in 1950‑51. Through Baghdad or London, the outreach of such books from or emulating Livorno for use by Jews of Iraqi origin can be said to have extended to ‘Baghdadi Jews’ commercial colonies in India, and probably Burma, Penang, South East Asia’s islands, and Hong Kong.

description: Annali di Ca’ Foscari. Serie orientale
ПОДКАСТ МЕДИА МАЙДОНИДА ЭНГ ОММАБОП ФОРМАТ СИФАТИДА
Creators: name: Мамбетирзаева, Несибели
Publisher: name: Zenodo
Year: 2024

description: Мазкур мақолада техник тараққиёт сабаб журналистикада пайдо бўлган янги формат ҳақида сўз этилган. Подкаст форматининг ўзига хослиги, абзаллиги, медиа майдонидаги ўрни очиб берилган. Қорақалпоғистон интернет журналистикаси мисолида таҳлил қилинган.
An Inequality for Gaussians on Lattices
Creators: name: Regev, Oded
name: Stephens-Davidowitz, Noah
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: Functional Analysis (math.FA)
subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: $ \newcommand{\R}{\ensuremath{\mathbb{R}}} \newcommand{\lat}{\mathcal{L}} \newcommand{\ensuremath}[1]{#1} $We show that for any lattice $\lat \subseteq \R^n$ and vectors $\vec{x}, \vec{y} \in \R^n$, \[ ρ(\lat + \vec{x})^2 ρ(\lat + \vec{y})^2 \leq ρ(\lat)^2 ρ(\lat + \vec{x} + \vec{y}) ρ(\lat + \vec{x} - \vec{y}) \; , \] where $ρ$ is the Gaussian measure $ρ(A) := \sum_{\vec{w} \in A} \exp(-π\| \vec{w} \|^2)$. We show a number of applications, including bounds on the moments of the discrete Gaussian distribution, various monotonicity properties of the heat kernel on flat tori, and a positive correlation inequality for Gaussian measures on lattices.
Khedacarus platypes Cook 1967
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Aturidae
Khedacarus
Khedacarus platypes

description: Khedacarus platypes Cook, 1967
Records from the study area: Maharashtra—Cook (1967); Prasad (1974).
Habitat: Hyporheic interstitial.
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 21, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
Artefato da Prototipação de módulos de mobilidade, adaptação ao contexto, interoperação de serviços e dados - Parcial
Creators: name: Nova, Alan Zuanella Vila
name: Aranda, Alex
name: Sousa, Fernando Maciel Lima E
name: Hiago Pereira Kanashiro
name: Alves, Julio Sergio Fernandes
name: Rodrigues, Leandro Veloso
name: De Siqueira, Priscila Fatima Pinheiro
name: Moreira, Rosiane Aparecida
name: Thiago Oliveira Hoerlle
name: Equipe Da Algar TI Consultoria S/A
name: De Sousa Júnior, Rafael Timóteo
name: De Mendonça, Fábio Lúcio Lopes
name: Nze, Georges Daniel Amvame
name: De Oliveira Albuquerque, Robson
name: Giozza, William Ferreira
name: Da Silva, Alex Mendes Pacheco
name: Almeida, Allan Filipe
name: De Moura, Ana Beatrice Neubauer
name: Da Silva, Ana Paula Bernadi
name: Vale, Ana Paula Morais
name: Ayra De Avila Almeida
name: Caetano, Caio Henrique
name: De Souza, Carlos Eduardo Ramalho
name: Cleuber Santos Silva
name: De Oliveira, Diego Martins
name: De Oliveira, Felipe Barreto
name: Praciano, Flavio Garcia
name: De Araújo, Gabriel Ribeiro
name: Alves, Guilherme Batista Meneses
name: Hiago Pereira Kanashiro
name: Martins, Isaac Silva
name: Pinto, Ismael Ithalo Barbosa
name: Da Costa E Silva Garcia, João Paulo
name: Joao Paulo Pimentel
name: Johnan Nicholas Reed
name: Klainer Mateus Estrela Gomes
name: De Oliveira Bezerra, Kelly Santos
name: Morais, Leonardo Jorge França
name: Reinaldi, Letícia Ramos
name: Da Silva Barbosa, Lucas
name: Luiz Augusto Dos Santos Pires
name: Ramos, Marcos Tércio
name: Domingues, Maria Karoline
name: Alves, Maria Tereza Correa Pacheco
name: Marilia Do Nascimento T. Valentim
name: Gomes, Orlando Werbeth Dos Santos
name: Rodrigues, Paulo Henrique Batista
name: Machado, Paulo Lima
name: Phelipe Alan Almeida
name: Rodrigues, Priscila Batista
name: Da Silva Camoes, Renato Jose
name: Thiago Leite De Souza
name: Schultz, Valeria Simas
name: Wellington Domingos Neves
Publisher: name: Zenodo
Year: 2023

description: Desenvolvimento e inovação visam realizar um estudo de inovações tecnológicas, nas áreas de tecnologia da informação, com ênfase na interoperabilidade de sistemas, gestão corporativa, processos de gestão, gerência de redes e gestão de dados, para áreas estratégicas da CoordenaçãoGeral de Tecnologia da Informação (CGTI) da Procuradoria-Geral da Fazenda Nacional – PGFN.
Axonopsis (Plesiobrachypoda) periyar Pesi
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Axonopsidae
Axonopsis
Axonopsis periyar

description: Axonopsis (Plesiobrachypoda) periyar Peši ć & Ranga Reddy, 2009
Records from the study area: Kerala—Pešić & Ranga Reddy (2009).
Habitat: The single specimen was taken in interstitial waters. However, the well-developed eye pigment suggests that the surface habitat may prove to be the more typical one (Pešić & Ranga Reddy 2009).
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 20, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
Additional file 1 of High-density lipoprotein cholesterol efflux capacity in patients with obstructive sleep apnea and its relation with disease severity
Creators: name: Fadaei, Reza
name: Mohassel Azadi, Samaneh
name: Rhéaume, Eric
name: Khazaie, Habibolah
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 1: S Figure 1. Cholesterol efflux capacities according to sex. a) Total, b) non-ABCA1, and c) ABCA1 CEC displayed no statistically remarkable difference between females and males in the whole population. d) Total CEC, e) Non-ABCA1 CEC, and f) ABCA1 CEC indicated no remarkable difference in males compared to females in both OSA patients and controls.
Autoimmunity in the Pathogenesis and Treatment of Keratoconjunctivitis Sicca
Creators: name: Davis, Richard M.
name: Liu, Katy C.
name: Huynh, Kyle
name: Grubbs, Joseph
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Dry eye is a chronic corneal disease that impacts the quality of life of many older adults. keratoconjunctivitis sicca (KCS), a form of aqueous-deficient dry eye, is frequently associated with Sjögren’s syndrome and mechanisms of autoimmunity. For KCS and other forms of dry eye, current treatments are limited, with many medications providing only symptomatic relief rather than targeting the pathophysiology of disease. Here, we review proposed mechanisms in the pathogenesis of autoimmune-based KCS: genetic susceptibility and disruptions in antigen recognition, immune response, and immune regulation. By understanding the mechanisms of immune dysfunction through basic science and translational research, potential drug targets can be identified. Finally, we discuss current dry eye therapies as well as promising new treatment options and drug therapy targets.
Spectral gap for random-to-random shuffling on linear extensions
Creators: name: Ayyer, Arvind
name: Schilling, Anne
name: Thiéry, Nicolas M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 60J10, 05C81, 06A07

description: In this paper, we propose a new Markov chain which generalizes random-to-random shuffling on permutations to random-to-random shuffling on linear extensions of a finite poset of size $n$. We conjecture that the second largest eigenvalue of the transition matrix is bounded above by $(1+1/n)(1-2/n)$ with equality when the poset is disconnected. This Markov chain provides a way to sample the linear extensions of the poset with a relaxation time bounded above by $n^2/(n+2)$ and a mixing time of $O(n^2 \log n)$. We conjecture that the mixing time is in fact $O(n \log n)$ as for the usual random-to-random shuffling.
description: 16 pages, 10 figures; v2: typos fixed plus extra information in figures; v3: added explicit conjecture 2.2 + Section 3.6 on the diameter of the Markov Chain as evidence + misc minor improvements; v4: fixed bibliography
Remembering Giovanni Cerri
Creators: name: Lomiento, Liana
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

An obituary of Giovanni Cerri (1 October 1940-5 September 2021).

description: Lexis
Targeting the molecular and cellular interactions of the bone marrow niche in immunologic disease topical collection on autoimmunity
Creators: name: Billard, Matthew J.
name: Brozowski, Jaime M.
name: Tarrant, Teresa K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Recent investigations have expanded our knowledge of the regulatory bone marrow (BM) niche, which is critical in maintaining and directing hematopoietic stem cell (HSC) self-renewal and differentiation. Osteoblasts, mesenchymal stem cells (MSCs), and CXCL12-abundant reticular (CAR) cells are niche components in close association with HSCs and have been more clearly defined in immune cell function and homeostasis. Importantly, cellular inhabitants of the BM niche signal through G protein-coupled surface receptors (GPCRs) for various appropriate immune functions. In this article, recent literature on BM niche inhabitants (HSCs, osteoblasts, MSCs, CAR cells) and their GPCR mechanistic interactions are reviewed for better understanding of the BM cells involved in immune development, immunologic disease, and current immune reconstitution therapies.
A cluster RCT and process evaluation of an implementation optimisation intervention to promote parental engagement enrolment and attendance in a childhood obesity prevention programme: results of the Optimising Family Engagement in HENRY (OFTEN) trial
Creators: name: Nixon, J.
name: Hartley, S.
name: Foy, R.
name: Collinson, M.
name: Burton, W.
name: Rutter, H.
name: Stevens, J.
name: Roberts, K.
name: Copsey, B.
name: Brown, J.
name: Farrin, A.J.
name: Tubeuf, S.
name: Bryant, M.
Publisher: name: BioMed Central Ltd
Year: 2021

description: Background: Poor and variable implementation of childhood obesity prevention programmes reduces their population impact and sustainability. We drew upon ethnographic work to develop a multi-level, theory-based implementation optimisation intervention. This intervention aimed to promote parental enrolment and attendance at HENRY (Health Exercise Nutrition for the Really Young), a UK community obesity prevention programme, by changing behaviours of children’s centre and local authority stakeholders. Methods: We evaluated the effectiveness of the implementation optimisation intervention on HENRY programme enrolment and attendance over a 12-month implementation period in a cluster randomised controlled trial. We randomised 20 local government authorities (with 126 children’s centres) to HENRY plus the implementation optimisation intervention or to HENRY alone. Primary outcomes were (1) the proportion of centres enrolling at least eight parents per programme and (2) the proportion of centres with a minimum of 75% of parents attending at least five of eight sessions per programme. Trial analyses adjusted for stratification factors (pre-randomisation implementation of HENRY, local authority size, deprivation) and allowed for cluster design. A parallel mixed-methods process evaluation used qualitative interviews and routine monitoring to explain trial results. Results: Neither primary outcome differed significantly between groups; 17.8% of intervention centres and 18.0% of control centres achieved the parent enrolment target (adjusted difference − 1.2%; 95% CI − 19.5%, 17.1%); 17.1% of intervention centres and 13.9% of control centres achieved the attendance target (adjusted difference 1.2%; 95% CI − 15.7%, 18.1%). Unexpectedly, the trial coincided with substantial national service restructuring, including centre closures and reduced funds. Some commissioning and management teams stopped or reduced delivery of both HENRY and the implementation optimisation intervention due to competing demands. Thus, at follow-up, HENRY programmes were delivered to approximately half the number of parents compared to baseline (n = 433 vs. 881). Conclusions: During a period in which services were reduced by external policies, this first definitive trial found no evidence of effectiveness for an implementation optimisation intervention promoting parent enrolment to and attendance at an obesity prevention programme. Trial registration: ClinicalTrials.govNCT02675699. Registered on 4 February 2016.
Additional file 2 of High-density lipoprotein cholesterol efflux capacity in patients with obstructive sleep apnea and its relation with disease severity
Creators: name: Fadaei, Reza
name: Mohassel Azadi, Samaneh
name: Rhéaume, Eric
name: Khazaie, Habibolah
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 2: S Figure 2. Cholesterol efflux capacities according to BMI categories. a) Total, b) Non-ABCA1, and c) ABCA1 CEC have shown no considerable change between normal weight (BMI < 25) and overweight (BMI > 25) in the whole population. d) Total CEC, e) Non-ABCA1 CEC, and f) ABCA1 CEC demonstrated no change in normal weight (BMI < 25) compared with overweight (BMI > 25) in both OSA patients and controls.
Sacrificial Calendar from Arcadia
Creators: name: Bianchi, Irene
name: Navarro Martínez, Vivian Lorena
name: Tentori Montalto, Marco
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description: The bronze tablet, with its 23 lines, presumably comes from Arcadia and can be dated to the first half of the 5th century BCE. Despite the fragmentary nature of the document, it is possible to identify some regulations of sacrifices and rites, and celebrations in honour of various deities. The sacrifices took place in different locations, many of which are otherwise unknown. The possibility that the sacrificial calendar was linked to sporting events, often interconnected with religious events, is also discussed.
description: Axon
Computer-aided verification in mechanism design
Creators: name: Barthe, Gilles
name: Gaboardi, Marco
name: Arias, Emilio Jesús Gallego
name: Hsu, Justin
name: Roth, Aaron
name: Strub, Pierre-Yves
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: In mechanism design, the gold standard solution concepts are dominant strategy incentive compatibility and Bayesian incentive compatibility. These solution concepts relieve the (possibly unsophisticated) bidders from the need to engage in complicated strategizing. While incentive properties are simple to state, their proofs are specific to the mechanism and can be quite complex. This raises two concerns. From a practical perspective, checking a complex proof can be a tedious process, often requiring experts knowledgeable in mechanism design. Furthermore, from a modeling perspective, if unsophisticated agents are unconvinced of incentive properties, they may strategize in unpredictable ways. To address both concerns, we explore techniques from computer-aided verification to construct formal proofs of incentive properties. Because formal proofs can be automatically checked, agents do not need to manually check the properties, or even understand the proof. To demonstrate, we present the verification of a sophisticated mechanism: the generic reduction from Bayesian incentive compatible mechanism design to algorithm design given by Hartline, Kleinberg, and Malekian. This mechanism presents new challenges for formal verification, including essential use of randomness from both the execution of the mechanism and from the prior type distributions. As an immediate consequence, our work also formalizes Bayesian incentive compatibility for the entire family of mechanisms derived via this reduction. Finally, as an intermediate step in our formalization, we provide the first formal verification of incentive compatibility for the celebrated Vickrey-Clarke-Groves mechanism.
Business Model Innovation in SMEs
Creators: name: Marques Peçanha, Lucio
Publisher: name: International Journal of Marketing, Innovation and Strategy
Year: 2023

description: To innovate in their business model, small and medium-sized enterprises (SMEs) have to be open to innovation, i.e., open to new technologies and sustainable practices among other possible strategies. The sustainability is crucial in this as the circular economy is growing as a new paradigm and the digital transformation and industry 4.0 are building knowledge around it. The organizations must, therefore, be aware of these contemporary practices and try to include the sustainable perspective into their business models. Many scholars produced knowledge related to business model and innovation, yet no systematic literature review (SLR) relating business model innovation to SMEs was found. Therefore, this SLR explains that phenomenon by answering to three research questions: (1) How the studies of business model innovation have evolved? (2) What are the challenges that SMEs have to struggle to innovate their business model? and (3) What are the trends in the study of business model innovation? A total of 247 documents retrieved from the Web of Science database were submitted to the analysis protocol. The final sample of 122 records was submitted to bibliometric analysis using the R software and VOSviewer software. Additionally, there was a content analysis of the articles to find trends, identifying clusters and presenting the results of condensed information in the form of tables and figures. Those results allowed the proposal of a framework for business model innovation in SME. At last, the conclusions and future studies agenda are presented to support new studies.
description: International Journal of Marketing, Innovation and Strategy, Articles in Press
Is Clinical Tolerance Possible after Allergen Immunotherapy?
Creators: name: Burks, A. Wesley
name: Moran, Timothy P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: There is a growing evidence that allergen immunotherapy (AIT) can provide significant and long-lasting clinical benefit for a number of allergic individuals. However, it is less clear if AIT results in clinical tolerance, which is characterized by a persistent state of clinical non-reactivity to allergens after therapy is finished. Addressing this knowledge gap is particularly relevant for patients undergoing AIT for food allergies, as anything less than complete tolerance could have potentially devastating consequences. An increasing number of studies, in particular those involving oral immunotherapy, are attempting to assess tolerance induction following AIT. Clinical tolerance does appear to be achievable in a subset of patients undergoing AIT, but whether this is equivalent to the type of tolerance observed in nonallergic individuals remains unknown. Developing established criteria for assessing tolerance induction, as well as the use of consistent terminology when describing clinical tolerance, will be important for determining the disease-modifying potential of AIT.
Hiding a Higgs width enhancement from off-shell gg (--> h*) --> ZZ measurements
Creators: name: Logan, Heather E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Measurements of the off-shell Higgs boson production cross section in gg (--> h*) --> ZZ have recently been used by the CMS and ATLAS collaborations to indirectly constrain the total width of the Higgs boson. I point out that the interpretation of these measurements as a Higgs width constraint can be invalidated if additional neutral Higgs boson(s) are present with masses below about 350 GeV.
description: 5 pages, 1 figure. v2: refs added, minor improvements to text. v3: expanded discussion, refs added, version accepted by PRD
title: Γεωστατιστική ανάλυση στάθμης υπογείων υδάτων σε υδροφορείς πορώδους τύπου στο υδατικό διαμέρισμα της Κρήτης
Creators: name: Χρυσανθη Μαρια
Publisher: name: Technical University of Crete
Year: 2024

description: Η γεωστατιστική ανάλυση παρέχει πληροφορία για τη χωρική κατανομή φυσικών
μεγεθών. Τα τελευταία αντιπροσωπεύονται από τη μαθηματική έννοια του
τυχαίου πεδίου. Για τη διερεύνηση των πεδίων αναπτύχθηκαν μέθοδοι χωρικής
παρεμβολής με περισσότερο διαδεδομένες τις μεθόδους Kriging. Στην παρούσα
εργασία πραγματοποιήθηκε εφαρμογή της μεθοδολογίας κανονικού Kriging για
δεδομένα μέσης στάθμης από 70 υδροσημεία της λεκάνης των Μοιρών. Για
την προετοιμασία των δεδομένων πραγματοποιήθηκαν έλεγχοι στασιμότητας,
κανονικότητας και ανισοτροπίας. Σκοπός της εργασίας ήταν η δημιουργία
χαρτών εκτίμησης της αναμενόμενης στάθμης. Ερευνήθηκαν δύο καταστάσεις
των δεδομένων. Η πρώτη εκτίμηση διεξήχθη από τα δεδομένα χωρίς διόρθωση ανισοτροπίας και η δεύτερη μετά από διόρθωση. Τα αποτελέσματα της
έρευνας παράγουν τους δύο χάρτες χωρικής εξάρτησης και υπολογίζουν ότι η
γεωμετρική ανισοτροπία των δεδομένων περιγράφεται από ανισοτροπικό λόγο
R=1.58. Τα μέτρα επιβεβαίωσης υπολογίστηκαν με μικρή απόκλιση για τις δύο
περιπτώσεις και δείχνουν πως ανισοτροπία αυτής της τάξης μεγέθους μπορεί
να αγνοηθεί. Τέλος, πραγματοποιήθηκε σύγκριση της εκτίμησης με χρήση ευκλείδειας και με χρήση μη ευκλείδειας απόστασης(απόσταση Manhattan). Οι
παραγόμενοι χάρτες από κάθε προσέγγιση ελέχθηκαν για την εγκυρότητά τους
μέσω της έκφρασης του Kriging για τη διασπορά των τιμών και με στατιστικά
μέτρα επιβεβαίωσης.
Wealth Transmission and Inequality among Hunter‐Gatherers
Creators: name: Gurven, Michael
name: Bell, Adrian
name: Hertz, Tom
name: Hill, Kim
name: Bowles, Samuel
name: Borgerhoff Mulder, Monique
name: Wiessner, Polly
name: Marlowe, Frank W.
name: Nolin, David
name: Smith, Eric Alden
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We report quantitative estimates of intergenerational transmission and population-wide inequality for wealth measures in a set of hunter-gatherer populations. Wealth is defined broadly as factors that contribute to individual or household well-being, ranging from embodied forms such as weight and hunting success to material forms such household goods, as well as relational wealth in exchange partners. Intergenerational wealth transmission is low to moderate in these populations, but is still expected to have measurable influence on an individual’s life chances. Wealth inequality (measured with Gini coefficients) is moderate for most wealth types, matching what qualitative ethnographic research has generally indicated (if not the stereotype of hunter-gatherers as extreme egalitarians). We discuss some plausible mechanisms for these patterns, and suggest ways in which future research could resolve questions about the role of wealth in hunter-gatherer social and economic life.
Acting and Behaving: The Philosopher in Ancient Greece and Late Modernity
Creators: name: La Matina, Marcello
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

Around the world scientific output has reached ungovernable levels; far more is written than can possibly be read. Also, there are increasingly clear signs of rampant conformity within the scientific community. Where does philosophy stand in all this? Can we continue to claim that the role of knowledgeable persons and the discourse with which they impart their knowledge are (free, individual) ways of acting? Or should both role and discourse be considered mere modes of (conformist, impersonal) behavior? By comparing modern practices to models of ancient Greek philosophy, philosophy of language enables us to reflect (especially historically) on the meaning of a life in theory, the role of logos, and the praxis within current discursive and philosophical practices. Our thesis is that the doing of the ancient philosopher (his form of life) works as a discourse, and that this discourse is also a discourse on the limits of language.

description: JoLMA
Response Diversity and Resilience in Social-Ecological Systems
Creators: name: McCabe, J. Terrence
name: Leslie, Paul
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Recent work in ecology suggests that the diversity of responses to environmental change among species contributing to the same ecosystem function can strongly influence ecosystem resilience. To render this important realization more useful for understanding coupled human-natural systems, we broaden the concept of response diversity to include heterogeneity in human decisions and action. Simply put, not all actors respond the same way to challenges, opportunities, and risks. The range, prevalence, and spatial and temporal distributions of different responses may be crucial to the resilience or the transformation of a social-ecological system, and thus have a bearing on human vulnerability and well-being in the face of environmental, socioeconomic, and political change. Response diversity can be seen at multiple scales (e.g., household, village, region) and response diversity at one scale may act synergistically with or contrary to the effects of diversity at another scale.
Applying the Behavior Change Technique Taxonomy to Four Multicomponent Childhood Obesity Interventions
Creators: name: Stevens, J.
name: Atkins, L.
name: Barkin, S.L.
name: Pratt, C.
name: Olayinka, O.
name: Kelly, A.M.
name: Veblen-Mortenson, S.
name: Nicastro, H.
name: Bangdiwala, S.I.
name: JaKa, M.M.
name: Moore, S.M.
name: Matheson, D.
name: Robinson, T.N.
name: Michie, S.
name: Adegbite-Adeniyi, C.
name: Po’e, E.K.
name: Sherwood, N.E.
name: Wood, C.
Publisher: name: SAGE Publications Inc.
Year: 2021

description: Applying the Behavior Change Technique Taxonomy has the potential to facilitate identification of effective childhood obesity intervention components. This article evaluates the feasibility of coding Childhood Obesity Prevention and Treatment Consortium interventions and compares reliability between external taxonomy-familiar coders and internal intervention-familiar coders. After training, coder pairs independently coded prespecified portions of intervention materials. An adjudication process was used to explore coding discrepancies. Reliability between internal and external coders was moderate (prevalence and bias-adjusted kappa.38 to.55). Reliability for specific target behaviors varied with substantial agreement for physical activity (.63 to.76) and moderate for dietary intake (.44 to.63). Applying the taxonomy to these interventions was feasible, but agreement was modest. Coding discrepancies highlight the importance of refining coding to capture the complexities of childhood obesity interventions, which often engage multiple recipients (e.g., parents and/or children) and address multiple behaviors (e.g., diet, physical activity, screen time).
Question Tags: The Case Study of ¿no ve? in the Spanish-Aymara Bilinguals’ Speech
Creators: name: Quartararo, Geraldine
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description: This article offers a first insight into tag questions description in Bolivian Spanish. In particular, it explores the pragmatic functions of tag question ¿no ve? in the variety of Bolivian Spanish spoken by Aymara-Spanish bilingual speakers. The analysis identifies the relation between the position of ¿no ve? and its pragmatic functions. Furthermore, it displays this tag question multidimensionality that may operate on different conversational layers at the same time. The study also describes the impact of social factors (sex, age and education) on the use of ¿no ve?. The original data used for the present analysis comes from the Corpus oral del español hablado por bilingües de aymara-español.
description: Rassegna iberistica