cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
“The right to narrate”: Gazans contest popular geopolitics with film
Creators: name: A.M. Nashef, Hania
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: Middle East--Palestine
subject: Area studies
subject: Motion pictures
subject: Self in literature
subject: Narration (Rhetoric)
subject: Imperialism

description: Since the Intifada of 2000, living conditions in the Gaza Strip have progressively deteriorated, and when Hamas came to power in 2006–07, a complete blockade was enforced on the inhabitants by Egypt and Israel. In addition, five full-scale wars have been waged on the Strip. Despite these conditions, Gazans remain resilient, as evidenced by several recent cultural productions. This article analyses a number of films that endeavour to show the human face of Gaza; and the way in which, amidst the ruins, Gazans construct a semblance of normal life. Films directed by Hany Abu-Assad, Rashid Masharawi, Arab/Tarzan Nasser, and Susan Youssef illustrate the hardships Gazans endure, but also navigate the complexity of their situation, allowing individual and communal stories to emerge. Abject reality and violence become secondary, as the protagonists are reconstituted in a way that challenges the confinement and politics of the territory.
A FRAMEWORK FOR ECONOMIC ANALYSIS OF NETWORK ARCHITECTURES
Creators: name: Karakus, Murat
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Networking and communications

description: This thesis firstly surveys and summarizes the state-of-the-art studies from two research areas in Software De fined Networking (SDN) architecture: (i) control plane scalability and (ii) Quality of Service (QoS)-related problems. It also outlines the potential challenges and open problems that need to be addressed further for more scalable SDN control planes and better and complete QoS abilities in SDN networks. The thesis secondly presents a hierarchical SDN design along with an inter-AS QoS-guaranteed routing approach. This design addresses the scalability problems of control plane and privacy concerns of inter-AS QoS routing philosophies in SDN. After exploring the roots of control plane scalability problems in SDN, the thesis then proposes a metric to quantitatively evaluate the control plane scalability in SDN. Later, the thesis presents a general framework for economic analysis of network architectures and designs. To this end, the thesis defines and utilizes two metrics, Unit Service Cost Scalability and Cost-to-Service, to evaluate how SDN architecture performs compared to MPLS architecture in terms of unit cost for a service and cost of introducing a new service along with giving mathematical models to calculate Capital Expenditures (CAPEX) and Operational Expenditures (OPEX) of a network. Moreover, the thesis studies the problem of optimal final pricing for services by proposing an optimal pricing scheme for a service request with QoS in SDN environment while aiming to maximize benefits of both service providers and customers. Finally, the thesis investigates how programmable network architectures, i.e. SDN, affect the network economics compared to traditional network architectures, i.e. MPLS, in case of failures along with exploring the economic impact of failures in different SDN control plane models.
Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin
Creators: name: Schultheis, Katherine
name: Schäfer, Hubert
name: Yung, Bryan S.
name: Oh, Janet
name: Muthumani, Karuppiah
name: Humeau, Laurent
name: Broderick, Kate E.
name: Smith, Trevor R.F.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2016
Subjects: subject: Guinea pig
subject: T cells
subject: ELISpot
subject: DNA vaccine
subject: Electroporation
subject: Skin
subject: 610 Medizin

description: The skin is an ideal target tissue for vaccine delivery for a number of reasons. It is highly accessible, and most importantly, enriched in professional antigen presenting cells. Possessing strong similarities to human skin physiology and displaying a defined epidermis, the guinea pig is an appropriate model to study epidermal delivery of vaccine. However, whilst we have characterized the humoral responses in the guinea pig associated with skin vaccine protocols we have yet to investigate the T cell responses. In response to this inadequacy, we developed an IFN-γ ELISpot assay to characterize the cellular immune response in the peripheral blood of guinea pigs. Using a nucleoprotein (NP) influenza pDNA vaccination regimen, we characterized host T cell responses. After delivery of the DNA vaccine to the guinea pig epidermis we detected robust and rapid T cell responses. The levels of IFN-γ spot-forming units averaged approximately 5000 per million cells after two immunizations. These responses were broad in that multiple regions across the NP antigen elicited a T cell response. Interestingly, we identified a number of NP immunodominant T cell epitopes to be conserved across an outbred guinea pig population, a phenomenon which was also observed after immunization with a RSV DNA vaccine. We believe this data enhances our understanding of the cellular immune response elicited to a vaccine in guinea pigs, and globally, will advance the use of this model for vaccine development, especially those targeting skin as a delivery site.
title: Anthurium :
title: Guidelines for the Conduct of Tests for Distinctness, Uniformity and Stability.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants..,
Publisher: name: International Union for the Protection of New Varieties of Plants
Year: 0
Subjects: New Varieties of Plants
Anthurium
Group identity

description: The purpose of these guidelines (“Test Guidelines”) is to elaborate the principles contained in the General Introduction (document TG/1/3), and its associated TGP documents, into detailed practical guidance for the harmonized examination of distinctness, uniformity and stability (DUS) and, in particular, to identify appropriate characteristics for the examination of DUS and production of harmonized variety descriptions.
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany
Creators: name: Porten, Klaudia
name: Rissland, Jürgen
name: Tigges, Almira
name: Broll, Susanne
name: Hopp, Wilfried
name: Lunemann, Mechthild
name: Treeck, Ulrich Van
name: Kimmig, Peter
name: Brockmann, Stefan
name: Wagner-Wiening, Christiane
name: Hellenbrand, Wiebke
name: Buchholz, Udo
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2006
Subjects: subject: Animals
subject: Humans
subject: Adolescent
subject: Adult
subject: Aged
subject: Middle Aged
subject: Child
subject: Preschool
subject: Female
subject: Male
subject: Sheep/microbiology
subject: Germany/epidemiology
subject: Age Distribution
subject: Disease Outbreaks
subject: Q Fever/epidemiology
subject: Q Fever/transmission
subject: Q Fever/veterinary
subject: Risk Factors
subject: Sex Distribution
subject: Sheep Diseases/transmission
subject: Zoonoses/epidemiology
subject: Zoonoses/transmission
subject: Aged 80 and over
subject: 610 Medizin

description: Background: In May 2003 the Soest County Health Department was informed of an unusually large number of patients hospitalized with atypical pneumonia. Methods: In exploratory interviews patients mentioned having visited a farmers' market where a sheep had lambed. Serologic testing confirmed the diagnosis of Q fever. We asked local health departments in Germany to identiy notified Q fever patients who had visited the farmers market. To investigate risk factors for infection we conducted a case control study (cases were Q fever patients, controls were randomly selected Soest citizens) and a cohort study among vendors at the market. The sheep exhibited at the market, the herd from which it originated as well as sheep from herds held in the vicinity of Soest were tested for Coxiella burnetii (C. burnetii). Results: A total of 299 reported Q fever cases was linked to this outbreak. The mean incubation period was 21 days, with an interquartile range of 16–24 days. The case control study identified close proximity to and stopping for at least a few seconds at the sheep's pen as significant risk factors. Vendors within approximately 6 meters of the sheep's pen were at increased risk for disease compared to those located farther away. Wind played no significant role. The clinical attack rate of adults and children was estimated as 20% and 3%, respectively, 25% of cases were hospitalized. The ewe that had lambed as well as 25% of its herd tested positive for C. burnetii antibodies. Conclusion: Due to its size and point source nature this outbreak permitted assessment of fundamental, but seldom studied epidemiological parameters. As a consequence of this outbreak, it was recommended that pregnant sheep not be displayed in public during the 3rd trimester and to test animals in petting zoos regularly for C. burnetii.
Innovative Tessellation Algorithm for Generating More Uniform Temperature Distribution in the Powder-bed Fusion Process
Creators: name: Maleki Pour, Ehsan
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Powder Bed Fusion Additive Manufacturing enables the fabrication of metal parts with complex geometry and elaborates internal features, the simpli cation of the assembly process, and the reduction of development time. However, the lack of consis-tent quality hinders its tremendous potential for widespread application in industry. This limits its ability as a viable manufacturing process particularly in the aerospace and medical industries where high quality and repeatability are critical. A variety of defects, which may be initiated during the powder-bed fusion additive manufacturing process, compromise the repeatability, precision, and resulting mechanical properties of the final part. The literature review shows that a non-uniform temperature distribution throughout fabricated layers is a signi cant source of the majority of thermal defects. Therefore, the work introduces an online thermography methodology to study temperature distribution, thermal evolution, and thermal speci cations of the fabricated layers in powder-bed fusion process or any other thermal inherent AM process. This methodology utilizes infrared technique and segmentation image processing to extract the required data about temperature distribution and HAZs of the layer under fabrication. We conducted some primary experiments in the FDM process to leverage the thermography technique and achieve a certain insight to be able to propose a technique to generate a more uniform temperature distribution. These experiments lead to proposing an innovative chessboard scanning strategy called tessellation algorithm, which can generate more uniform temperature distribution and diminish the layer warpage consequently especially throughout the layers with either geometry that is more complex or poses relatively longer dimensions. In the next step, this work develops a new technique in ABAQUS to verify the proposed scanning strategy. This technique simulates temperature distribution throughout a layer printed by chessboard printing patterns in powder-bed fusion process in a fraction of the time taken by current methods in the literature. This technique compares the temperature distribution throughout a designed layer printed by three presented chessboard-scanning patterns, namely, rastering pattern, helical pattern, and tessellation pattern. The results con rm that the tessellation pattern generates more uniform temperature distribution compared with the other two patterns. Further research is in progress to leverage the thermography methodology to verify the simulation technique. It is also pursuing a hybrid closed-loop online monitoring (OM) and control methodology, which bases on the introduced tessellation algorithm and online thermography in this work and Arti cial Neural Networking (ANN) to generate the most possible uniform temperature distribution within a safe temperature range layer-by-layer.
Additional file 3 of Barriers and facilitators to the recruitment of disabled people to clinical trials: a scoping review
Creators: name: Shariq, Sameed
name: Cardoso Pinto, Alexandra M
name: Budhathoki, Shyam Sundar
name: Miller, Marie
name: Cro, Suzie
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Science Policy
Hematology

description: Additional file 3. PRISMA Extension for Scoping Reviews Completed Fillable Checklist.
Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR
Creators: name: Dauber, Bianca
name: Martinez-Sobrido, Luis
name: Schneider, Jana
name: Hai, Rong
name: Waibler, Zoe
name: Kalinke, Ulrich
name: Garcis-Sastre, Adolfo
name: Wolff, Thorsten
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2009
Subjects: subject: Cell Line
subject: Tumor
subject: Humans
subject: Female
subject: Active Transport
subject: Cell Nucleu
subject: Animals
subject: Cells
subject: Cultured
subject: Cytoplasm/metabolism
subject: Enzyme Activation
subject: Influenza B virus/genetics
subject: Influenza B virus/pathogenicity
subject: Influenza B virus/physiology
subject: Mice
subject: Inbred C57BL
subject: Microscopy
subject: Fluorescenc
subject: Models
subject: Biological
subject: Phosphorylation
subject: RNA
subject: Double-Stranded/metabolism
subject: RNA-Binding Proteins/genetics
subject: RNA-Binding Proteins/metabolism
subject: Ribonucleoproteins/metabolism
subject: Viral Nonstructural Proteins/genetics
subject: Viral Nonstructural Proteins/metabolism
subject: Viral Proteins/metabolism
subject: Virus Replication
subject: eIF-2 Kinase/metabolism
subject: 610 Medizin

description: Activation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational shutdown. A major gap in our understanding of PKR's antiviral properties concerns the nature of the kinase activating molecules expressed by influenza and other viruses with a negative strand RNA genome, as these pathogens produce little or no detectable amounts of dsRNA. Here we systematically investigated PKR activation by influenza B virus and its impact on viral pathogenicity. Biochemical analysis revealed that PKR is activated by viral ribonucleoprotein (vRNP) complexes known to contain single-stranded RNA with a 5'-triphosphate group. Cell biological examination of recombinant viruses showed that the nucleo-cytoplasmic transport of vRNP late in infection is a strong trigger for PKR activation. In addition, our analysis provides a mechanistic explanation for the previously observed suppression of PKR activation by the influenza B virus NS1 protein, which we show here to rely on complex formation between PKR and NS1's dsRNA binding domain. The high significance of this interaction for pathogenicity was revealed by the finding that attenuated influenza viruses expressing dsRNA binding-deficient NS1 proteins were rescued for high replication and virulence in PKR-deficient cells and mice, respectively. Collectively, our study provides new insights into an important antiviral defense mechanism of vertebrates and leads us to suggest a new model of PKR activation by cytosolic vRNP complexes, a model that may also be applicable to other negative strand RNA viruses.
Additional file 2 of ACLY as a modulator of liver cell functions and its role in Metabolic Dysfunction-Associated Steatohepatitis
Creators: name: Convertini, Paolo
name: Santarsiero, Anna
name: Todisco, Simona
name: Gilio, Michele
name: Palazzo, Donatella
name: Pappalardo, Ilaria
name: Iacobazzi, Dominga
name: Frontuto, Maria
name: Infantino, Vittoria
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Virology

description: Additional file 2: Figure S1. Effect of HCA and RWP on primary human hepatocyte cell viability. Figure S2. ACLY gene silencing reduces oxidative stress in TNFα triggered hepatocytes. Figure S3. Effect of RWP on lipid accumulation and oxidative stress in TNFα-triggered human hepatocytes. Figure S4. ACLY-dependent NF-kB binding to ACLY gene. Figure S5. RWP affected IL-6 and IL-1β pro-inflammatory cytokines secretion in human hepatocytes.
Additional file 1 of Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects
Creators: name: Wang, Yufei
name: Buck, Alicia
name: Piel, Brandon
name: Zerefa, Luann
name: Murugan, Nithyassree
name: Coherd, Christian D.
name: Miklosi, Andras G.
name: Johal, Haraman
name: Bastos, Ricardo Nunes
name: Huang, Kun
name: Ficial, Miriam
name: Laimon, Yasmin Nabil
name: Signoretti, Sabina
name: Zhong, Zhou
name: Hoang, Song-My
name: Kastrunes, Gabriella M.
name: Grimaud, Marion
name: Fayed, Atef
name: Yuan, Hsien-Chi
name: Nguyen, Quang-De
name: Thai, Tran
name: Ivanova, Elena V.
name: Paweletz, Cloud P.
name: Wu, Ming-Ru
name: Choueiri, Toni K.
name: Wee, Jon O.
name: Freeman, Gordon J.
name: Barbie, David A.
name: Marasco, Wayne A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 1: Supplementary Figure 1. Quantification of CAIX expression on Tet-On inducible CAIX expressing skrc-59 cells comparing to MMNK-1 and skrc-59 cells. (A) Quantification of CAIX expression on Tet-On inducible CAIX expressing skrc-59 cells treated with 100 ng/mL Dox for 120 hours in total. Quantification was performed on 19 time points, 0, 6, 12, 18, 24, 30, 36, 42, 48, 54, 60, 66, 72, 78, 84, 90, 96, 108, 120h. Two arrows indicate the time points of 48 and 96h when the culture media was replaced with fresh one considering the half-life of Dox. (B) CAIX quantification results of skrc-59, MMNK-1, and Tet-On inducible CAIX expressing system were shown in the table
title: Sebastian Koch, Identitätskrisen nach dem Ende des Britischen Empire: Zur kulturellen Neu-Verortung in Kanada, Australien und Aotearoa Neuseeland
Creators: name: Segesser, Daniel
Publisher: name: Max Weber Stiftung
Year: 2025
Subjects: subject: 9

description: German Historical Institute London Bulletin, vol. 47, no. 1GHI London Bulletin 2025, Bd. 47, Nr. 1, p. 118
Radar Characteristics Study for the Development of Surrogate Roadside Objects
Creators: name: Lin, Jun
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Electrical engineering not elsewhere classified
Digital processor architectures
Other information and computing sciences not elsewhere classified

description: Driving safety is a very important topic in vehicle development. One of the biggest threat of driving safety is road departure. Many vehicle active safety technologies have been developed to warn and mitigate road departure in recent years. In order to evaluate the performance of road departure warning and mitigation technologies, the standard testing environment need to be developed. The testing environment shall be standardized to provide consistent and repeatable features in various locations worldwide and in various seasons. The testing environment should also be safe to the vehicle under test in case the safety features do not function well. Therefore, soft, durable and reusable surrogates of roadside objects need to be used. Meanwhile, all surrogates should have the same representative characteristics of real roadside objects to different automotive sensors (e.g. radar, LIDAR and camera). This thesis describes the study on identifying the radar characteristics of common roadside objects, metal guardrail, grass, and concrete divider, and the development of the required radar characteristics of surrogate objects. The whole process is divided into two steps. The fi rst step is to find the proper methods to measure the radar properties of those three roadside objects. The measurement result of each roadside object will be used as the requirement for making its surrogate. The second step is to create the material for developing the surrogate of each roadside object. In the experimental results demonstrate that all three surrogates satisfy their radar characteristics requirements.
sj-docx-1-heb-10.1177_10901981211025471 – Supplemental material for Measuring Early Childhood Educators’ Physical Activity and Sedentary Behavior–Related Self-Efficacy: A Systematic Review of Tools
Creators: name: Szpunar, Monika
name: Bruijns, Brianne
name: Tucker, Patricia
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-heb-10.1177_10901981211025471 for Measuring Early Childhood Educators’ Physical Activity and Sedentary Behavior–Related Self-Efficacy: A Systematic Review of Tools by Monika Szpunar, Brianne Bruijns and Patricia Tucker in Health Education & Behavior
Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release
Creators: name: Votteler, Jörg
name: Iavnilovitch, Elena
name: Fingrut, Orit
name: Shemesh, Vivian
name: Taglicht, Daniel
name: Erez, Omri
name: Sörgel, Stefan
name: Walther, Torsten
name: Bannert, Norbert
name: Schubert, Ulrich
name: Reiss, Yuval
Publisher: name: Robert Koch-Institut
Year: 2009
Subjects: subject: Western
subject: Cell Line
subject: Humans
subject: Virus Replication
subject: Mutation
subject: Blotting
subject: HIV-1/genetics
subject: Immunoprecipitation
subject: Binding Sites/genetics
subject: Calcium-Binding Proteins/genetics
subject: Calcium-Binding Proteins/metabolism
subject: Cell Cycle Proteins/genetics
subject: Cell Cycle Proteins/metabolism
subject: HIV-1/physiology
subject: Hela Cells
subject: Protein Binding
subject: Recombinant Proteins/metabolism
subject: Substrate Specificity
subject: Transfection
subject: Ubiquitin-Protein Ligases/genetics
subject: Ubiquitin-Protein Ligases/metabolism
subject: Ubiquitination
subject: Virus Assembly
subject: 610 Medizin

description: Background: The ALG2-interacting protein X (ALIX)/AIP1 is an adaptor protein with multiple functions in intracellular protein trafficking that plays a central role in the biogenesis of enveloped viruses. The ubiquitin E3-ligase POSH (plenty of SH3) augments HIV-1 egress by facilitating the transport of Gag to the cell membrane. Recently, it was reported, that POSH interacts with ALIX and thereby enhances ALIX mediated phenotypes in Drosophila. Results: In this study we identified ALIX as a POSH ubiquitination substrate in human cells: POSH induces the ubiquitination of ALIX that is modified on several lysine residues in vivo and in vitro. This ubiquitination does not destabilize ALIX, suggesting a regulatory function. As it is well established that ALIX rescues virus release of L-domain mutant HIV-1, HIV-1ΔPTAP, we demonstrated that wild type POSH, but not an ubiquitination inactive RING finger mutant (POSHV14A), substantially enhances ALIX-mediated release of infectious virions derived from HIV-1ΔPTAP L-domain mutant (YPXnL-dependent HIV-1). In further agreement with the idea of a cooperative function of POSH and ALIX, mutating the YPXnL-ALIX binding site in Gag completely abrogated augmentation of virus release by overexpression of POSH. However, the effect of the POSH-mediated ubiquitination appears to be auxiliary, but not necessary, as silencing of POSH by RNAi does not disturb ALIX-augmentation of virus release. Conclusion: Thus, the cumulative results identified ALIX as an ubiquitination substrate of POSH and indicate that POSH and ALIX cooperate to facilitate efficient virus release. However, while ALIX is obligatory for the release of YPXnL-dependent HIV-1, POSH, albeit rate-limiting, may be functionally interchangeable.
"Teaching Shakespeare in a Time of Hate." Shakespeare Survey 74 (2021): 15-29
Creators: name: Joubin, Alexa Alice
name: Starks, Lisa S.
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: Shakespeare, William, 1564-1616
subject: Teaching
subject: Racism
subject: Feminism
subject: Ethics

description: This article examines new theories and praxis of listening for silenced voices and of telling compelling stories that make us human. Elucidation of our Levinas-inspired theories of the Other is followed by a discussion of classroom practices for in-person and remote instruction that foster collaborative knowledge building and intersectional pedagogy. The moral agency that comes with the cultivation of ethical treatment of one another can lead to political advocacy. Special attention is given to race, gender, and the exigencies of social justice and remote learning in the era of the global pandemic of COVID-19 (2019 novel coronavirus disease). The new normal in higher education, which is emerging at the time of writing, exposes inequities that were previously veiled by on-campus life and resources. Even as they are cause for grief and anxiety, the inequities exposed by COVID-19 can spur change for the better.
Open Insight Sessions: One Year with the Irish Monitor - Future Pathways & Community Insights
Creators: name: Grypari, Ioanna
name: Catalano, Jessica
name: Hrynaszkiewicz, Iain
Publisher: name: Zenodo
Year: 2025
Subjects: OpenAIRE
National monitor
open access

description: The Open Insight Sessions series is designed to deepen community engagement with the Irish Monitor, strengthen institutional adoption, and gather valuable user feedback. Across five monthly sessions, we’ll review achievements, address data quality, explore collaborative potential, and create opportunities for institutions to share their experiences. These sessions aim to build a robust, sustainable foundation for the Monitor. Each session begins with a short webinar (20-minute presentation and 10-minute Q&A), followed by a 30-minute interactive segment where attendees can participate in hands-on activities and discussions. Presentations and recordings from each session will be posted on Zenodo and subsequently shared on the Irish Monitor engagement and training page.

This concluding session of the Open Insights series reflects on the pilot phase of the Irish National Open Access Monitor and opens the floor to discuss its future. Guest contributors include Jessica Catalano (CSIL) from PathOS, a Horizon Europe project focused on understanding and measuring the impacts of Open Science, and Iain Hrynaszkiewicz (PLOS) from OSMI, an international initiative working toward a common framework for Open Science monitoring. Together, we will explore how monitoring can become more meaningful, sustainable, and actionable for institutions, funders, and policymakers in Ireland.

Presenters:Ioanna Grypari, OpenAIREJessica Catalano, CSILIain Hrynaszkiewicz, PLOS

 

Agenda:

Pilot Reflections - Successes, challenges, and what Irish organisations told us during the pilot.

Guest Insight: PathOS - Jessica Catalano, CSILWhat can evidence from Open Science impact pathways and cost-benefit analysis case studies tell us about how to design monitoring that is meaningful and focused on real value?

Guest Insight: OSMI (10 min) - Iain Hrynaszkiewicz, PLOSHow can shared principles and community-led approaches help build credible and useful Open Science monitoring frameworks?

Open Discussion

Date: 8 May 2025

Recording: https://youtu.be/qzNOUkbU7KU
sj-pdf-1-sgo-10.1177_21582440211031216 – Supplemental material for The Hegemony’s Contest in the South China Sea
Creators: name: Teixeira, Victor Alexandre G.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: 160299 Criminology not elsewhere classified
subject: FOS: Law
subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-sgo-10.1177_21582440211031216 for The Hegemony’s Contest in the South China Sea by Victor Alexandre G. Teixeira in SAGE Open
Data from: Females translate male mRNA transferred during mating
Creators: name: Allan, Carson W
name: Pigage, Helen K.
name: McCoy, John
name: Green, Clinton
name: Matzkin, Luciano Matias
name: Jefferey Callan
name: Delahunt, Stephen
name: Gonzalez, Fernando Diaz
name: Bono, Jeremy M.
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Life Sciences
subject: Ecology and Evolutionary Biology
subject: Entomology

description: Genome annotations, InterPro domain analsis, and protemoics analisis and other data related to the paper.
DO BELIEFS ABOUT RACE DIFFERENCES IN PAIN CONTRIBUTE TO ACTUAL RACE DIFFERENCES IN EXPERIMENTAL PAIN RESPONSE?
Creators: name: Mehok, Lauren
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Clinical psychology

description: Chronic pain is a costly health problem that affects more than 100 million people in the United States. Race differences exist in the way that pain is experienced and in how it is treated. Many biopsychosocial factors contribute to race differences in pain tolerance. Beliefs about race differences in pain sensitivity may be one of these factors. Previous research has identified that individuals’ explicit beliefs about their gender group influence their own pain tolerance on a cold pressor task. Explicit beliefs about race and pain sensitivity have also been identified but have yet to be linked to actual pain tolerance. Implicit beliefs about race are well documented; however, little is known about the extent to which individuals hold implicit beliefs about race differences in pain sensitivity or whether these beliefs contribute to actual race differences in pain. My thesis examined explicit and implicit beliefs about race and pain and explored whether these beliefs moderated race differences in pain tolerance. I found that White participants had a higher pain tolerance than Black participants on the cold pressor task, U=1165.50, pt(131)=-6.83, pt(131)=6.35, pb=-0.37, p=.71, and implicit, b=-21.87, p=.65, beliefs failed to moderate the relationship between race and pain tolerance. Further exploration indicated that participants’ comparisons of their own pain sensitivity to that of their race group moderated the relationship between race and pain tolerance, ⍵=4.40, p=.04. These results provide further insight into race differences in pain tolerance. Researchers may consider examining explicit and implicit beliefs about race differences in pain in health care providers to better understand disparities in pain related recommendations.
Additional file 1 of The relationship between stigma and psychological distress among people with diabetes: a meta-analysis
Creators: name: Guo, Xiajun
name: Wu, Sijia
name: Tang, Haishan
name: Li, Yuanyuan
name: Dong, Wanglin
name: Lu, Guangli
name: Liang, Shuang
name: Chen, Chaoran
Publisher: name: figshare
Year: 2024
Subjects: Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Supplementary Material 1
Additional file 1 of Characterizing reference genes for high-fidelity gene expression analysis under different abiotic stresses and elicitor treatments in fenugreek leaves
Creators: name: Ebrahimi, Amin
name: Gharanjik, Shahrokh
name: Azadvari, Elham
name: Rashidi-Monfared, Sajad
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1
Compressed Convolutional Neural Network for Autonomous Systems
Creators: name: Pathak, Durvesh
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Autonomous vehicle systems
Electrical engineering not elsewhere classified
Digital processor architectures
Other information and computing sciences not elsewhere classified

description: The word “Perception” seems to be intuitive and maybe the most straightforward problem for the human brain because as a child we have been trained to classify images, detect objects, but for computers, it can be a daunting task. Giving intuition and reasoning to a computer which has mere capabilities to accept commands and process those commands is a big challenge. However, recent leaps in hardware development, sophisticated software frameworks, and mathematical techniques have made it a little less daunting if not easy. There are various applications built around to the concept of “Perception”. These applications require substantial computational resources, expensive hardware, and some sophisticated software frameworks. Building an application for perception for the embedded system is an entirely different ballgame. Embedded system is a culmination of hardware, software and peripherals developed for specific tasks with imposed constraints on memory and power. Therefore, the applications developed should keep in mind the memory and power constraints imposed due to the nature of these systems.Before 2012, the problems related to “Perception” such as classification, object detection were solved using algorithms with manually engineered features. However, in recent years, instead of manually engineering the features, these features are learned through learning algorithms. The game-changing architecture of Convolution Neural Networks proposed in 2012 by Alex K, provided a tremendous momentum in the direction of pushing Neural networks for perception. This thesis is an attempt to develop a convolution neural network architecture for embedded systems, i.e. an architecture that has a small model size and competitive accuracy. Recreate state-of-the-art architectures using fire module’s concept to reduce the model size of the architecture. The proposed compact models are feasible for deployment on embedded devices such as the Bluebox 2.0. Furthermore, attempts are made to integrate the compact Convolution Neural Network with object detection pipelines.
Alternative Assembly Pathways of the 20S Proteasome and Non-canonical Complexes
Creators: name: Panfair, Dilrajkaur
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Plant cell and molecular biology
Animal cell and molecular biology
Biochemistry and cell biology not elsewhere classified

description: The 20S proteasome, a multi-subunit protease complex, present in all domains of life and some orders of bacteria, is involved in degradation of the majority of cellular proteins. Structurally, it is made of α and β subunits arranged in four heptameric rings, with inner two β-rings sandwiched between outer two α-rings. The 20S proteasome in prokaryotes usually has one type of α and one type of β subunits, whereas eukaryotes have seven distinct types of α and seven distinct types of β subunits. Unlike the highly conserved structure of proteasome, its assembly pathway is different across the domains. In archaea and eukaryotes, proteasome assembly begins with α subunit interactions leading to the α-ring formation. By contrast, bacterial proteasome assembly pathway bypasses the α-ring formation step by initiating assembly through an α and β subunit interaction first. These early interactions are not well understood due to their highly rapid and dynamic nature. This dissertation focused on understanding the early events in proteasome assembly and contributed three significant findings. First, the archaeal proteasome assembly can also begin without formation of α-rings, demonstrating the coexistence of a bacterial-like assembly pathway. Second, a novel assembly intermediate was identified in yeast, and its composition argues for the presence of a similar α-ring independent assembly pathway. Third, the assembly chaperone Pba3-Pba4 prevents the formation of high molecular weight complexes arising from spontaneous and non-productive interactions among the α subunits. These findings provide a broader understanding of proteasome biogenesis and suggest considering proteasome assembly event as a network of interactions rather than a linear pathway. The results also shed light on assembly chaperone’s contribution in increasing the efficiency of proteasome assembly by streamlining the productive interactions.
Spatiotemporal Analysis of Invasive Meningococcal Disease, Germany
Creators: name: Elias, Johannes
name: Harmsen, Dag
name: Claus, Heike
name: Hellenbrand, Wiebke
name: Frosch, Matthias
name: Vogel, Ulrich
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2006
Subjects: subject: Humans
subject: Serotyping
subject: Cluster Analysis
subject: Retrospective Studies
subject: Meningococcal Infections/epidemiology
subject: Neisseria meningitidis/classification
subject: Vaccination
subject: 610 Medizin

description: Meningococci can cause clusters of disease. Specimens from 1,616 patients in Germany obtained over 42 months were typed by serogrouping and sequence typing of PorA and FetA and yielded a highly diverse dataset (Simpson's index 0.963). A retrospective spatiotemporal scan statistic (SaTScan) was applied in an automated fashion to identify clusters for each finetype defined by serogroup variable region (VR) VR1 and VR2 of the PorA and VR of the FetA. A total of 26 significant clusters (p< or =0.05) were detected. On average, a cluster consisted of 2.6 patients. The median population in the geographic area of a cluster was 475,011, the median cluster duration was 4.0 days, and the proportion of cases in spatiotemporal clusters was 4.2%. The study exemplifies how the combination of molecular finetyping and spatiotemporal analysis can be used to assess an infectious disease in a large European country.
Additional file 1 of Barriers and facilitators to the recruitment of disabled people to clinical trials: a scoping review
Creators: name: Shariq, Sameed
name: Cardoso Pinto, Alexandra M
name: Budhathoki, Shyam Sundar
name: Miller, Marie
name: Cro, Suzie
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Science Policy
Hematology

description: Additional file 1. Detailed review search strategy. Full search strategy applied used to search MEDLINE and EMBASE via Ovid.
Lasiopodomys (Stenocranius) raddei
Creators: name: Sheremetyeva, I. N.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Lasiopodomys
Lasiopodomys raddei

description: 14. Lasiopodomys (St.) raddei (Poliakov 1881) — поΛёвка РаΑΑе
 Lasiopodomys (St.) raddei — криптический виΑ, который на основании моΛекуΛярно-генетических Αанных и резуΛьтатов экспериментаΛьной гибриΑизации неΑавно приобреΛ свою самостоятеΛьность от узкочерепной поΛёвки (Petrova et al. 2015; 2016). Обитание виΑа приурочено к территории юго-восточного ЗабайкаΛья и Восточной МонгоΛии в преΑеΛах от 40 ° Αо 50.60 ° северной широты и от 115.68 ° Αо 118.61 ° восточной ΑоΛготы. При этом особи L. raddei могут встречаться симпатрически с узкочерепной поΛёвкой. По мнению ряΑа авторов, граница ареаΛа виΑа, вероятно, ограничена на северо-запаΑе Λесом, распоΛоженным вΑоΛь рек ШиΛка и ИнгоΑа, а на юге и юго-востоке рекой УΛΑза (Lissovsky et al. 2013; Petrova et al. 2016).
description: Published as part of Sheremetyeva, I. N., 2023, Species composition and distribution of gray voles in Transbaikalia and the Russian Far East, pp. 724-743 in Amurian Zoological Journal XV (4) on page 733, DOI: 10.33910/2686-9519-2023-15-4-724-743, http://zenodo.org/record/11362261
Additional file 1 of The economic effect of financial compensation in China’s healthcare system: comprehensive insights regarding supply and demand factors
Creators: name: Guo, Yi
name: Hong, Xuezhi
name: Li, Dongmei
name: An, Qiannan
name: Fan, Wenwen
name: Yang, Minghe
name: Xiao, Luyang
Publisher: name: figshare
Year: 2024
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Supplementary Material 1
Exploring Regional Twin Transition Paths - Employing an Empirical Agent Based Model on Knowledge Creation
Creators: name: Bürscher, Theresa
name: Jäger, Katharina
name: Neuländtner, Martina
name: Scherngell, Thomas
Publisher: name: Zenodo
Year: 2025

description: The twin transition, encompassing both digital and green transition, is a key challenge for Europe. In this study, we shift attention to the twin transition of technological knowledge bases of European regions. We employ an empirically grounded agent-based model (ABM) that allows to simulate technological knowledge creation – as captured by patents – of innovative agents in green and digital domains. Aggregated to the regional level, we use the model output to explore how local micro-level knowledge creation dynamics shape the regional twin transition progress. The twin transition trajectories are then further analysed through the lens of regional path development, meaning that the type of paths regions follow in the process of greening and digitalizing their knowledge bases are identified.
Analysis of Pseudo-Symmetry in Protein Homo-Oligomers
Creators: name: Rajendran, Catherine Jenifer Rajam
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Other information and computing sciences not elsewhere classified

description: Symmetry plays a significant role in protein structural assembly and function. This is especially true for large homo-oligomeric protein complexes due to stability and finite control of function. But, symmetry in proteins are not perfect due to unknown reasons and leads to pseudosymmetry. This study focuses on symmetry analysis of homo-oligomers, specifically homo-dimers, homo-trimers and homo-tetramers. We defined Off Symmetry (OS) to measure the overall symmetry of the protein and Structural Index (SI) to quantify the structural difference and Assembly Index (AI) to quantify the assembly difference between the subunits. In most of the symmetrical homo-trimer and homo-tetramer proteins, Assembly Index contributes more to Off Symmetry and in the case of homo-dimer, Structural index contributes more than the Assembly Index. The main chain atom Carbon-Alpha (CA) is more symmetrical than the first side chain atom Carbon-Beta (CB), suggesting protein mobility may contribute to the pseudosymmetry. In addition, Pearson coefficient correlation between their Off-Symmetry and their respective atoms B-Factor (temperature factor) are calculated. We found that the individual residues of a protein in all the subunits are correlated to their average B-Factor of these residues. The correlation with BFactor is stronger in Structure Index than Assembly Index. All these results suggest that protein dynamics play an important role and therefore a larger off-symmetry may indicate a more mobile and flexible protein complex.
Rozum, idea, filologia. Historia intelektualna w kontekstach literatury
Creators: name: Junkiert, Maciej
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: Intellectual life
subject: History
subject: Polish literature
subject: Poland
subject: Area studies
subject: Romanticism
subject: Idea (Philosophy)
subject: Gadamer, Hans-Georg, 1900-2002

description: REASON, IDEA, PHILOLOGY INTELLECTUAL HISTORY IN LITERARY CONTEXTS (WRITTEN ON THE MARGINS OF CYPRIAN NORWID’S “MILCZENIE” (“SILENCE”)) The article examines the 19th century evolution of history of ideas and its relatedness to literary studies. The debate whether philology, philosophy, and history are autonomous humanistic disciplines or they make up a part of what is informally referred to as “humanities” or “humanistic sciences” lasted for the whole century. The idea, seen as a notion connected with philosophy of cognition, became the central part of the debate. In the present paper I suggest an interpretation of Cyprian Norwid’s essay Milczenie (Silence) as a text designed by the poet to enter this debate.
Aastaks 2025 Eestile üks põhja- ja lõunalinnakuga ülikoolihaigla
Creators: name: Starkopf, Joel
name: Talving, Peep
name: Siigur, Urmas
name: Peedu, Agris
name: Luts, Katrin
name: Asser, Toomas
Publisher: name: Eesti Arst
Year: 2018

description: Eesti Arst 2018; 97(4):179–180
description: Eesti Arst, Aprill 2018
sj-pdf-1-jbx-10.1177_24725552211026270 – Supplemental material for Phenotypic Screening Following Transcriptomic Deconvolution to Identify Transcription Factors Mediating Axon Growth Induced by a Kinase Inhibitor
Creators: name: Lowell, Jeffrey A.
name: O’Neill, Nicholas
name: Danzi, Matt C.
name: Al-Ali, Hassan
name: Bixby, John L.
name: Lemmon, Vance P.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-jbx-10.1177_24725552211026270 for Phenotypic Screening Following Transcriptomic Deconvolution to Identify Transcription Factors Mediating Axon Growth Induced by a Kinase Inhibitor by Jeffrey A. Lowell, Nicholas O’Neill, Matt C. Danzi, Hassan Al-Ali, John L. Bixby and Vance P. Lemmon in SLAS Discovery
Experimental Validation of Non-Cohesive Soil using Discrete Element Method
Creators: name: Roy, Ayan
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: In this thesis, an explicit time integration code which integrates multibody dynamics (MBD) and the discrete element method (DEM) is validated using three previously published steady-state physical experiments for non-cohesive sand-type material, namely: shear-cell for measuring shear stress versus normal stress; penetroplate pressure-sinkage test; and wheel drawbar pull-torque-slip test. The test results are used to calibrate the material properties of the DEM soft soil model and validate the coupled MBD-DEM code. All three tests are important because each test measures specific mechanical characteristics of the soil under various loading conditions. Shear strength of the soil as a function of normal load help to understand shearing of the soil under a vehicle wheel contact patch causing loss of traction. Penetroplate pressure-sinkage test is used to calibrate and validate friction and shear strength characteristics of the soil. Finally the rigid wheel-soil interaction test is used to predict drawbar pull force and wheel torque vs. slip percentage and normal stress for a rigid wheel. Wheel-Soil interaction test is important because it plays the role of ultimate validation of the soil model tuned in the previous two experiments and also shows how the soil model behaves in vehicle mobility applications.
 All the aforementioned tests were modeled in the multibody dynamics software using rigid bodies and various joints and actuators. The sand-type material is modeled using discrete cubical particles. A penalty technique is used to impose normal contact constraints (including particle-particle and particle-wall contact). An asperity-based friction model is used to model friction. A Cartesian Eulerian grid contact search algorithm is used to allow fast contact detection between particles. A recursive bounding box contact search algorithm enabled fast contact detection between the particles and polygonal body surfaces (such as walls, penetrometer, and wheel). The governing equations of motion are solved along with contact constraint equations using a time-accurate explicit solution procedure. The results show very good agreement between the simulation and the experimental measurements. The model is then demonstrated in a full-scale application of high-speed off-road vehicle mobility on the sand-type soil.
Virge Pall: tänu Scandiatransplantiga liitumisele on abi saanud kaheksa Eesti patsienti
Creators: name: Filippov, Madis
Publisher: name: Eesti Arst
Year: 2018

description: Eesti Arst 2018; 97(4):181–183
description: Eesti Arst, Aprill 2018
Kokkuvõte kliinilisest auditist „Täiskasvanute kõrgvererõhktõve käsitlus esmatasandil“
Creators: name: Rätsep, Anneli
name: Kalda, Ruth
name: Martinson, Katrin
name: Asi, Signe
name: Gross, Lilli
name: Poom, Katrin
name: Lõmps, Pille
name: Unukainen, Tiina
name: Joona, Sirli
Publisher: name: Eesti Arst
Year: 2018

description: Eesti Arst 2018; 97(4):185–190
description: Eesti Arst, Aprill 2018