cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Near Infrared Spectra of Type Ia Supernovae
Creators: name: Marion, G. H.
name: Höflich, P.
name: Vacca, W. D.
name: Wheeler, J. C.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report near infrared (NIR) spectroscopic observations of twelve ``Branch-normal'' Type Ia supernovae (SNe Ia) which cover the wavelength region from 0.8-2.5 microns. Our sample more than doubles the number of SNe Ia with published NIR spectra within three weeks of maximum light. The epochs of observation range from thirteen days before maximum light to eighteen days after maximum light. A detailed model for a Type Ia supernovae is used to identify spectral features. The Doppler shifts of lines are measured to obtain the velocity and, thus, the radial distribution of elements. The NIR is an extremely useful tool to probe the chemical structure in the layers of SNe Ia ejecta. This wavelength region is optimal for examining certain products of the SNe Ia explosion that may be blended or obscured in other spectral regions. We identify spectral features from MgII, CaII, SiII, FeII, CoII, NiII and possibly MnII. We find no indications for hydrogen, helium or carbon in the spectra. The spectral features reveal important clues about the physical characteristics of SNe Ia. We use the features to derive upper limits for the amount of unburned matter, to identify the transition regions from explosive carbon to oxygen burning and from partial to complete silicon burning, and to estimate the level of mixing during and after the explosion.
description: 44 pages, 7 figures, 3 tables, accepted by ApJ
Simultaneous determination of $Ω_{\rm M0}$ and $H_0$ from joint Sunyaev-Zeldovich effect and X-ray observations with median statistics
Creators: name: Sereno, M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Clusters of galaxies contain a fair sample of the universal baryonic mass fraction. A combined analysis of the intracluster medium (ICM) within their hydrostatic regions, as derived from both Sunyaev-Zeldovich effect (SZE) measurements and X-ray images, makes it possible to constrain the cosmological parameters. We consider both gas fraction estimates and angular diameter distance measurements. Adopting median statistics, we find, at the 2-$σ$ level, the pressureless matter density, $Ω_{\rm M0}$, to be between 0.30 and 0.40 and the Hubble constant, $H_0$, between 44 and 66 Km s$^{-1}$ Mpc$^{-1}$.
description: 8 pages, 2 figures, to appear in A&A
Proton Decay and Axion Dark Matter in SO(10) Grand Unification via Minimal Left-Right Symmetry
Creators: name: Hamada, Yuta
name: Ibe, Masahiro
name: Muramatsu, Yu
name: Oda, Kin-ya
name: Yokozaki, Norimi
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the proton lifetime in the $SO(10)$ Grand Unified Theory (GUT), which has the left-right (LR) symmetric gauge theory below the GUT scale. In particular, we focus on the minimal model without the bi-doublet Higgs field in the LR symmetric model, which predicts the LR-breaking scale at around $10^{10\text{--}12}$ GeV. The Wilson coefficients of the proton decay operators turn out to be considerably larger than those in the minimal $SU(5)$ GUT model especially when the Standard Model Yukawa interactions are generated by integrating out extra vector-like multiplets. As a result, we find that the proton lifetime can be within the reach of the Hyper-Kamiokande experiment even when the GUT gauge boson mass is in the $10^{16\text{--}17}$ GeV range. We also show that the mass of the extra vector-like multiplets can be generated by the Peccei-Quinn symmetry breaking in a consistent way with the axion dark matter scenario.
description: 20 pages, 3 figures (v1); Minor revision, references added (v2)
Hyperlipidemias in elderly patients: results from the Berlin Aging Study II (BASEII), a cross-sectional study
Creators: name: Rosada, Adrian
name: Kassner, Ursula
name: Weidemann, Felix
name: König, Maximilian
name: Buchmann, Nikolaus
name: Steinhagen-Thiessen, Elisabeth
name: Spira, Dominik
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Hyperlipidemia
subject: prevalence
subject: treatment targets
subject: elderly patients
subject: cardiovascular disease
subject: Lipoprotein(a)
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Hyperlipidemias are common and the last decades have seen substantially growing evidence of their causative role in the development of atherosclerosis and subsequent cardiovascular diseases. Since hyperlipidemias usually do not cause direct clinical symptoms, they often remain undiagnosed until a serious cardiovascular event occurs. Especially for LDL-hypercholesteremia, there are well-established treatment options available to prevent the occurrence of atherosclerosis. However, there is a lack of knowledge regarding the proper treatment of elderly patients. The goal of this study was to assess the prevalence of hyperlipidemia in a group of young and a group of elderly community-dwelling participants and to determine to what extent treatment of hyperlipidemia should be initiated or required. Methods: Crossectional data from a total of 2151 subjects (1657 in the elderly group, mean age 69, and 494 in the young group (control group), mean age 29) of the Berlin Aging Study II (BASE-II) were available. Medical history was assessed and recorded by trained physicians and prevalence of lipid disorders was determined with laboratory tests, including a lipid-profile. Results: A large proportion of subjects (39%) were unaware of an existing lipid disorder. The prevalence of hyperlipidemia was more frequent in the elderly group (76%) compared to the young group (41%). Hypercholesterolemia was the most common diagnosed disorder (64%), followed by hyperlipoproteinemia(a) (18%), hypertriglyceridemia (7%) and combined hyperlipoproteinaemia (5%). Only a minority of this cohort was treated with lipid-lowering medication (17%) and of those treatment targets according to ESC guidelines were reached only in 16.5 %. Conclusions: Hyperlipidemias appear underdiagnosed and undertreated. As the prevalence of these disorders increases with age and with regard to their role as a major modifiable risk factor for cardiovascular disease it seems to be advisable to aim for more consistent and sustainable screening and treatment of these common disorders. Trial registration: BASE-II registered with the clinical trial registry Deutsches Register Klinischer Studien (DRKS00009277).
Nitrogen Mineralization and Microbial Biomass Dynamics in Different Tropical Soils Amended with Contrasting Organic Resources
Creators: name: Omari, Richard
name: Sonoko Bellingrath-Kimura, Dorothea
name: Fujii, Yoshiharu
name: Sarkodee-Addo, Elsie
name: Appiah Sarpong, Kwame
name: Oikawa, Yosei
Publisher: name: Humboldt-Universität zu Berlin
Year: 2018
Subjects: subject: organic residues
subject: microbial biomass
subject: organic carbon
subject: nitrogen mineralization
subject: agro-ecological zone
subject: 630 Landwirtschaft und verwandte Bereiche

description: The use of location-specific and underutilized organic residues (OR) as soil amendments in small-holder agro-ecosystems is promising. Six ORs (Leucaena leucocephala, Centrosema pubescens, Gliricidia sepium, Pueraria phaseoloides, Azadirachta indica, and Theobroma cacao) were amended to three tropical soils each at 24 mg g−1 dry soil in 120-day incubation study to estimate their nitrogen (N) mineralization and microbial biomass carbon (C) dynamics. Inorganic N contents varied among ORs, soil type and incubation days. Regardless of soil type, Gliricidia had the highest inorganic N among the studied ORs. Mineralization rate of 1.4 to 1.5 mg N kg−1 soil day−1 was observed for Lego and Tec soils, respectively, and was twice higher than Nya soil. However, Nya soil released higher inorganic N than Tec and Lego soils, implying high N mineralization efficiency in the former. Consistent soil pH increase was respectively observed for Theobroma and Pueraria treatments in all soils. Moreover, Theobroma and Pueraria amendments showed the highest soil microbial biomass C (MBC) at the end of the incubation. The assessed soil properties likely affected by the dominant edaphic factors and management influenced differences in MBC and dissolved organic carbon (DOC) while OR quality indices controlled N mineralization. Thus, we conclude that soil properties and OR type are important factors for optimal utilization of organic resources.
Survey of charge symmetry breaking operators for dd -> alpha pi0
Creators: name: Gardestig, A.
name: Horowitz, C. J.
name: Nogga, A.
name: Fonseca, A. C.
name: Hanhart, C.
name: Miller, G. A.
name: Niskanen, J. A.
name: van Kolck, U.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The charge-symmetry-breaking amplitudes for the recently observed d d -> alpha pi0 reaction are investigated. Chiral perturbation theory is used to classify and identify the leading-order terms. Specific forms of the related one- and two-body tree level diagrams are derived. As a first step toward a full calculation, a few tree-level two-body diagrams are evaluated at each considered order, using a simplified set of d and alpha wave functions and a plane-wave approximation for the initial dd state. The leading-order pion-exchange term is shown to be suppressed in this model because of poor overlap of the initial and final states. The higher-order one-body and short-range (heavy-meson-exchange) amplitudes provide better matching between the initial and final states and therefore contribute significantly and coherently to the cross section. The consequences this might have for a full calculation, with realistic wave functions and a more complete set of amplitudes, are discussed.
description: REVTeX 4, 35 pages, 8 eps figures, submitted to PRC
Myzophyllobothrium rubrum , Shipley and Hornell 1906
Creators: name: Jensen, Kirsten
name: Pen, Isabel A. M.
name: Caira, Janine N.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Platyhelminthes
Cestoda
Tetraphyllidea
Phyllobothriidae
Myzophyllobothrium
Myzophyllobothrium rubrum

description: Myzophyllobothrium rubrum Shipley and Hornell, 1906
(Fig. 4A)
 Type and only known host: Whitespotted eagle ray, Aetobatus ocellatus (as Aetobatis [sic] narinari) (Myliobatiformes: Aetobatidae).
 Type locality: Puttalam Lake, Sri Lanka (as Ceylon).
 Additional localities: None.
 Site of infection: Spiral intestine.
 Specimens examined: BMNH nos. 2006.7.14.1–3, three slides identified by Southwell (1925) as Myzophyllobothrium rubrum (see Jensen and Caira 2006).
 Sequence data: None.
 Remarks. Joyeux and Baer (1961) resolved the issue surrounding the two different interpretations of the scolex of this species presented by Shipley and Hornell (1906). In their figure of the scolex of one of the co-types of the species, Joyeux and Baer (1961; fig. 290) illustrated the anterior region of the scolex to clearly consist of four biloculate bothridia rather than four simple suckers. Unfortunately, we have been unable to locate the co-types of this species. The specimens of M. rubrum on the three slides examined here were reported by Southwell (1925) as having been collected from the type host and locality. Unfortunately, all of these specimens are in relatively poor condition, and include only one scolex. We did not consider this material to be of sufficient quality to allow re-description of this species. Nonetheless, given the paucity of information available on the proglottid anatomy of M. rubrum, a photograph of the posterior region of a mature proglottid of one of these specimens is presented in Fig. 4A.
description: Published as part of Jensen, Kirsten, Pen, Isabel A. M. & Caira, Janine N., 2021, A revision of the Rhoptrobothriidae (Cestoda: " Tetraphyllidea "), pp. 201-218 in Zootaxa 4999 (3) on page 207, DOI: 10.11646/zootaxa.4999.3.1, http://zenodo.org/record/5118878
On three-periodic trajectories of multi-dimensional dual billiards
Creators: name: Tabachnikov, Serge
Publisher: name: arXiv
Year: 2003
Subjects: subject: Dynamical Systems (math.DS)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 37J45, 70H12

description: We consider the dual billiard map with respect to a smooth strictly convex closed hypersurface in linear 2m-dimensional symplectic space and prove that it has at least 2m distinct 3-periodic orbits.
description: Published by Algebraic and Geometric Topology at http://www.maths.warwick.ac.uk/agt/AGTVol3/agt-3-33.abs.html
On the contact geometry of nodal sets
Creators: name: Komendarczyk, R.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Differential Geometry (math.DG)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: 58J05 (Primary) 53D10 (Secondary)

description: In the 3-dimensional Riemannian geometry, contact structures equipped with an adapted Riemannian metric are divergence-free, nondegenerate eigenforms of the Laplace-Beltrami operator. We trace out a 2-d analogue of this fact: there is a close relationship between the topology of the contact structure on a convex surface in the 3-manifold (the dividing curves) and the nodal curves of Laplacian eigenfunctions on that surface. Motivated by this relationship, we consider a topological version of Payne's conjecture for the free membrane problem. We construct counterexamples to Payne's conjecture for closed Riemannian surfaces. In light of the correspondence between the nodal lines and dividing curves, we interpret Payne's conjecture in terms of the tight versus overtwisted dichotomy for contact structures.
description: 17 pages, 1 figure
Base metal-catalyzed dehydrogenation of formic acid and alcohols
Creators: name: Zhou, Wei
Publisher: name: Universität Rostock
Year: 2019
Subjects: subject: 333.7 Natural resources, energy and environment
subject: 540 Chemistry & allied sciences

description: The content of this thesis is about base metal catalyzed dehydrogenation reactions and it contains two parts. In the first part, a cobalt catalyzed formic acid dehydrogenation in aqueous media is disclosed. The second part deals with a manganese catalyzed dehydrogenation of alcohols which was developed by in-situ combination of manganese pentacarbonyl bromide with phosphine free oxamide ligands.
Sminthurus bourgeoisi Nayrolles 1995
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Sminthuridae
Sminthurus
Sminthurus bourgeoisi

description: Sminthurus bourgeoisi Nayrolles, 1995
Sminthurus bourgeoisi Nayrolles, 1995b: 221.
DISTRIBUTION. — Hérault. Olargues (Nayrolles 1995b).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 408, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
The X-ray and extreme-ultraviolet flux evolution of SS Cygni throughout outburst
Creators: name: Wheatley, Peter J.
name: Mauche, Christopher W.
name: Mattei, Janet A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the most complete multiwavelength coverage of any dwarf nova outburst: simultaneous optical, Extreme Ultraviolet Explorer, and Rossi X-ray Timing Explorer observations of SS Cygni throughout a narrow asymmetric outburst. Our data show that the high-energy outburst begins in the X-ray waveband 0.9--1.4d after the beginning of the optical rise and 0.6d before the extreme-ultraviolet rise. The X-ray flux drops suddenly, immediately before the extreme-ultraviolet flux rise, supporting the view that both components arise in the boundary layer between the accretion disc and white dwarf surface. The early rise of the X-ray flux shows the propagation time of the outburst heating wave may have been previously overestimated. The transitions between X-ray and extreme-ultraviolet dominated emission are accompanied by intense variability in the X-ray flux, with timescales of minutes. As detailed by Mauche & Robinson, dwarf nova oscillations are detected throughout the extreme-ultraviolet outburst, but we find they are absent from the X-ray lightcurve. X-ray and extreme-ultraviolet luminosities imply accretion rates of 3e15g/s in quiescence, 1e16g/s when the boundary layer becomes optically thick, and \~1e18g/s at the peak of the outburst. The quiescent accretion rate is two and a half orders of magnitude higher than predicted by the standard disc instability model, and we suggest this may be because the inner accretion disc in SS Cyg is in a permanent outburst state.
description: 15 pages, 14 figures; accepted for publication in MNRAS
Prediction of advanced fibrosis in non-alcoholic fatty liver disease using gut microbiota-based approaches compared with simple non-invasive tools
Creators: name: Lang, Sonja
name: Farowski, Fedja
name: Martin, Anna
name: Wisplinghoff, Hilmar
name: Vehreschild, Maria J. G. T .
name: Krawczyk, Marcin
name: Nowag, Angela
name: Kretzschmar, Anne
name: Scholz, Claus
name: Kasper, Philipp
name: Roderburg, Christoph
name: Lammert, Frank
name: Goeser, Tobias
name: Steffen, Hans-Michael
name: Demir, Münevver
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: fibrosis
subject: NAFLD
subject: non-alcoholic fatty liver disease
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Liver fibrosis is the major determinant of liver related complications in patients with non-alcoholic fatty liver disease (NAFLD). A gut microbiota signature has been explored to predict advanced fibrosis in NAFLD patients. The aim of this study was to validate and compare the diagnostic performance of gut microbiota-based approaches to simple non-invasive tools for the prediction of advanced fibrosis in NAFLD. 16S rRNA gene sequencing was performed in a cohort of 83 biopsy-proven NAFLD patients and 13 patients with non-invasively diagnosed NAFLD-cirrhosis. Random Forest models based on clinical data and sequencing results were compared with transient elastography, the NAFLD fibrosis score (NFS) and FIB-4 index. A Random Forest model containing clinical features and bacterial taxa achieved an area under the curve (AUC) of 0.87 which was only marginally superior to a model without microbiota features (AUC 0.85). The model that aimed to validate a published algorithm achieved an AUC of 0.71. AUC's for NFS and FIB-4 index were 0.86 and 0.85. Transient elastography performed best with an AUC of 0.93. Gut microbiota signatures might help to predict advanced fibrosis in NAFLD. However, transient elastography achieved the best diagnostic performance for the detection of NAFLD patients at risk for disease progression.
First-principles investigation of the assumptions underlying Model-Hamiltonian approaches to ferromagnetism of 3d impurities in III-V semiconductors
Creators: name: Mahadevan, Priya
name: Zunger, Alex
Publisher: name: arXiv
Year: 2003
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: We use first-principle calculations for transition metal impurities V, Cr, Mn, Fe, Co and Ni in GaAs as well as Cr and Mn in GaN, GaP and GaSb to identify the basic features of the electronic structure of these systems. The microscopic details of the hole state such as the symmetry and the orbital character, as well as the nature of the coupling between the hole and the transition metal impurity are determined. This could help in the construction of model Hamiltonians to obtain a description of various properties beyond what current first-principle methods are capable of.
description: 14 figures
Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy
Creators: name: Klehmet, Juliane
name: Beutner, Svenja
name: Hoffmann, Sarah
name: Dornauer, Matthias
name: Paul, Friedemann
name: Reilmann, Ralf
name: Brandt, Alexander U.
name: Meisel, Andreas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: CIDP
subject: Clinical outcome parameter
subject: CIDP subgroups
subject: Case control studies
subject: Diagnostic test assessment
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: In patients suffering from Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) disease severity is assessed by Medical Research Counsil (MRC) Scale or Inflammatory Neuropathy Cause and Treatment (INCAT) disability score. However, none of these methods is appropriate to objectively assess muscle weakness or to detect very small subclinical changes. More objective and quantitative measures are needed in order to evaluate treatment efficiency or to detect subclinical affection of upper limps for early diagnosis. The goal of our study was to objectively quantify muscular weakness in CIDP patients with the non-invasive Quantitative Motor (Q-Motor) test of Grip Force Assessment (QGFA) as well as the Involuntary Movement Assessment (QIMA) and to search for differences between typical and atypical CIDP variants. In addition, we hypothesized that Q-Motor findings correlate with disease severity scales such as MRC or INCAT score. Methods: In this cross-sectional exploratory proof-of-concept study subjects with confirmed diagnosis of typical or atypical CIDP were examined and compared to healthy controls (HC). For Q-Motor tests all subjects had to lift a device (250 g and 500 g) equipped with an electromagnetic sensor that measured grip force (GF) and three-dimensional changes in position and orientation. The measures "grip force variability" (GFV), "position index" (PI) and "orientation index" (OI) were provided to assess involuntary movements due to muscular weakness. Results: 33 patients with CIDP and 28 HC were included. All measures were significantly elevated in CIDP patients for both devices in the right and left hand compared to healthy controls. Subgroup analysis revealed no differences between typical and atypical CIDP variants. INCAT score only weakly correlated with OI and PI. However, there was a stronger correlation between MRC and QIMA parameters in both hands. Conclusion: Q-Motor assessments were capable to objectively assess muscular weakness in CIDP. In particular, QIMA measures detected subclinical generalized muscle weakness even in patients with milder disability. Sensitivity and rater-independence of Q-Motor assessments support a further exploration of QIMA measures as potential endpoints for future clinical trials in CIDP.
Shadowing Effects on the Nuclear Suppression Factor, R_dAu, in d+Au Interactions
Creators: name: Vogt, R.
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We explore how nuclear modifications to the nucleon parton distributions affect production of high transverse momentum hadrons in deuteron-nucleus collisions. We calculate the charged hadron spectra to leading order using standard fragmentation functions and shadowing parameterizations. We obtain the d+Au to pp ratio both in minimum bias collisions and as a function of centrality. The minimum bias results agree reasonably well with the BRAHMS data while the calculated centrality dependence underestimates the data and is a stronger function of p_T than the data indicate.
description: 18 pages, 3 figures, final version, Phys. Rev. C in press
Sminthurus bozoulensis Nayrolles 1995
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Sminthuridae
Sminthurus
Sminthurus bozoulensis

description: Sminthurus bozoulensis Nayrolles, 1995
Sminthurus bozoulensis Nayrolles, 1995b: 222.
DISTRIBUTION. — Aveyron. Montrozier, causse Comtal, 620 m (Nayrolles 1995b).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 408, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272
A case report of an excellent response to interferon- α in a patient with functional metastasized neuroendocrine tumor refractory to other treatments
Creators: name: Özdirik, Burcin
name: Tacke, Frank
name: Benz, Fabian
name: Amthauer, Holger
name: Fehrenbach, Uli
name: Roderburg, Christoph
name: Jann, Henning
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: antiproliferative
subject: antisecretory
subject: case report
subject: efficacy
subject: interferon
subject: neuroendocrine tumor
subject: toxicity
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Interferon alpha (IFNα) has been used for a long time in patients with functionally active neuroendocrine tumors (NET). However, due to the unfavorable toxicity profile of interferon, the perceived limited efficacy as well as the development of novel substances, IFNα is only used sparingly in the treatment of NET to date. Patients concerns and diagnosis: We describe the case of a 63-year-old male patient with highly differentiated, functional NET of the ileum and synchronous liver metastasis. Interventions: After failure of classical therapies including dose-intensified somatostatin analog treatment and palliative primary tumor resection, a therapy with pegylated IFNα2a (135 μg/wk) was initiated. Following this treatment, the patient fully recovered from signs of hypersecretion and demonstrated an impressive tumor response. Outcomes: Thirty months after initiating IFNα, the patient is still free of clinical symptoms and shows a sustained tumor response. Notably, no relevant side effects were observed. Conclusion: Our case report supports the use of IFNα in patients with functional NET refractory to classical treatments.
The low-frequency properties of FR0 radio galaxies
Creators: name: Capetti, Alessandro
name: Baldi, Ranieri D.
name: Brienza, Marisa
name: Morganti, Raffaella
name: Giovannini, Gabriele
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Using the Alternative Data Release of the TIFR GMRT Sky Survey (TGSS), we studied the low-frequency properties of FR0 radio galaxies, the large population of compact radio sources associated with red massive early-type galaxies revealed by surveys at 1.4 GHz. We considered TGSS observations from FR0CAT, a sample formed by 104 FR0s at z<0.05: all but one of them are covered by the TGSS, and 43 of them are detected above a 5 sigma limit of 17.5 mJy. No extended emission has been detected around the FR0s, corresponding to a luminosity limit of < 4 10^23 W/Hz over an area of 100 kpc x 100 kpc. All but eight FR0s have a flat or inverted spectral shape (alpha < 0.5) between 150 MHz and 1.4 GHz: this spectral behavior confirms the general paucity of optically thin extended emission within the TGSS beam, as is expected for their compact 1.4 GHz morphology. Data at 5 GHz were used to build their radio spectra, which are also generally flat at higher frequencies. By focusing on a sub-sample of FR0s with flux density > 50 mJy at 1.4 GHz, we found that ~75% of them have a convex spectrum, but with a smaller curvature than the more powerful gigahertz peaked-spectrum sources (GPS). The typical FR0s radio spectrum is better described by a gradual steepening toward high frequencies, rather than to a transition from an optically-thick to an optically-thin regime, possibly observed in only ~15% of the sample.
description: Accepted for publication in A&A
ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage
Creators: name: Neumaier, Hannah Louise
name: Harel, Shelly
name: Klingel, Karin
name: Kaya, Ziya
name: Heuser, Arnd
name: Kespohl, Meike
name: Beling, Antje
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: myocarditis
subject: proteasome
subject: immunoproteasome inhibitor
subject: inflammation
subject: proteostasis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Inhibition of proteasome function by small molecules is highly efficacious in cancer treatment. Other than non-selective proteasome inhibitors, immunoproteasome-specific inhibitors allow for specific targeting of the proteasome in immune cells and the profound anti-inflammatory potential of such compounds revealed implications for inflammatory scenarios. For pathogen-triggered inflammation, however, the efficacy of immunoproteasome inhibitors is controversial. In this study, we investigated how ONX 0914, an immunoproteasome-selective inhibitor, influences CoxsackievirusB3 infection in NMRI mice, resulting in the development of acute and chronic myocarditis, which is accompanied by formation of the immunoproteasome in heart tissue. In groups in which ONX 0914 treatment was initiated once viral cytotoxicity had emerged in the heart, ONX 0914 had no anti-inflammatory effect in the acute or chronic stages. ONX 0914 treatment initiated prior to infection, however, increased viral cytotoxicity in cardiomyocytes, promoting infiltration of myeloid immune cells into the heart. At this stage, ONX 0914 completely inhibited the β5 subunit of the standard cardiac proteasome and less efficiently blocked its immunoproteasome counterpart LMP7. In conclusion, ONX 0914 unselectively perturbs cardiac proteasome function in viral myocarditis of NMRI mice, reduces the capacity of the host to control the viral burden and promotes cardiac inflammation.
Surrogate-assisted performance prediction for data-driven knowledge discovery algorithms: application to evolutionary modeling of clinical pathways
Creators: name: Funkner, Anastasia A.
name: Yakovlev, Aleksey N.
name: Kovalchuk, Sergey V.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The paper proposes and investigates an approach for surrogate-assisted performance prediction of data-driven knowledge discovery algorithms. The approach is based on the identification of surrogate models for prediction of the target algorithm's quality and performance. The proposed approach was implemented and investigated as applied to an evolutionary algorithm for discovering clusters of interpretable clinical pathways in electronic health records of patients with acute coronary syndrome. Several clustering metrics and execution time were used as the target quality and performance metrics respectively. An analytical software prototype based on the proposed approach for the prediction of algorithm characteristics and feature analysis was developed to provide a more interpretable prediction of the target algorithm's performance and quality that can be further used for parameter tuning.
Aerococcus urinae – A potent biofilm builder in endocarditis
Creators: name: Yaban, Berrin
name: Kikhney, Judith
name: Musci, Michele
name: Petrich, Annett
name: Schmidt, Julia
name: Hajduczenia, Maria
name: Schoenrath, Felix
name: Falk, Volkmar
name: Moter, Annette
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Aerococcus
subject: Endocarditis, Bacterial
subject: Heart Valves
subject: In Situ Hybridization, Fluorescence
subject: Urinary Tract Infections
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The diagnosis of infective endocarditis (IE) remains a challenge. One of the rare bacterial species recently associated with biofilms and negative cultures in infective endocarditis is Aerococcus urinae. Whether the low number of reported cases might be due to lack of awareness and misidentification, mainly as streptococci, is currently being discussed. To verify the relevance and biofilm potential of Aerococcus in endocarditis, we used fluorescence in situ hybridization to visualize the microorganisms within the heart valve tissue. We designed and optimized a specific FISH probe (AURI) for in situ visualization and identification of A. urinae in sections of heart valves from two IE patients whose 16S rRNA gene sequencing had deteced A. urinae. Both patients had a history of urinary tract infections. FISH visualized impressive in vivo grown biofilms in IE, thus confirming the potential of A. urinae as a biofilm pathogen. In both cases, FISH/PCR was the only method to unequivocally identify A. urinae as the only causative pathogen for IE. The specific FISH assay for A. urinae is now available for further application in research and diagnostics. A. urinae should be considered in endocarditis patients with a history of urinary tract infections. These findings support the biofilm potential of A. urinae as a virulence factor and are meant to raise the awareness of this pathogen.
Induced quantum metric fluctuations and the validity of semiclassical gravity
Creators: name: Hu, B. L.
name: Roura, Albert
name: Verdaguer, Enric
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We propose a criterion for the validity of semiclassical gravity (SCG) which is based on the stability of the solutions of SCG with respect to quantum metric fluctuations. We pay special attention to the two-point quantum correlation functions for the metric perturbations, which contain both intrinsic and induced fluctuations. These fluctuations can be described by the Einstein-Langevin equation obtained in the framework of stochastic gravity. Specifically, the Einstein-Langevin equation yields stochastic correlation functions for the metric perturbations which agree, to leading order in the large $N$ limit, with the quantum correlation functions of the theory of gravity interacting with $N$ matter fields. The homogeneous solutions of the Einstein-Langevin equation are equivalent to the solutions of the perturbed semiclassical equation, which describe the evolution of the expectation value of the quantum metric perturbations. The information on the intrinsic fluctuations, which are connected to the initial fluctuations of the metric perturbations, can also be retrieved entirely from the homogeneous solutions. However, the induced metric fluctuations proportional to the noise kernel can only be obtained from the Einstein-Langevin equation (the inhomogeneous term). These equations exhibit runaway solutions with exponential instabilities. A detailed discussion about different methods to deal with these instabilities is given. We illustrate our criterion by showing explicitly that flat space is stable and a description based on SCG is a valid approximation in that case.
description: 28 pages, REVTeX4, 2 figures
MOESM1 of Production of xylooligosaccharides and monosaccharides from poplar by a two-step acetic acid and peroxide/acetic acid pretreatment
Creators: name: Wen, Peiyao
name: Zhang, Tian
name: Wang, Jinye
name: Lian, Zhina
name: Zhang, Junhua
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Plant Biology

description: Additional file 1: Table S1. The AC concentration and recovery of AC pretreatment liquor. Figure S1. XRD analysis of raw and two steps treated. Figure S2. FT-IR spectrum of raw and two steps pretreated poplar. Figure S3. XPS analysis of raw and two steps pretreated poplar. Figure S4. Hydrophobicity of raw and two steps pretreated poplar. Figure S5. SEM analysis of raw and two steps pretreated poplar. Figure S6. Effect of CTec2 loading on the hydrolysis of poplar (2%) pretreated by AC (5%, 170 °C, 30 min) for 48 h.
Branch, Spur, and Feather Formation in Spiral Galaxies
Creators: name: Chakrabarti, S.
name: Laughlin, G.
name: Shu, F. H.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We use hydrodynamical simulations to investigate the response of geometrically thin, self-gravitating, singular isothermal disks of gas to imposed rigidly rotating spiral potentials. By minimizing reflection-induced feedback from boundaries, and by restricting our attention to models where the swing parameter $X \sim 10$, we minimize the swing amplification of global normal modes even in models where Toomre's $Q_g \sim 1-2$ in the gas disk. We perform two classes of simulations: short-term ones over a few galactic revolutions where the background spiral forcing is large, and long-term ones over many galactic revolutions where the spiral forcing is considerably smaller. In both classes of simulations, the initial response of the gas disk is smooth and mimics the driving spiral field. At late times, many of the models evince substructure akin to the so-called branches, spurs, and feathers observed in real spiral galaxies. We comment on the parts played respectively by ultraharmonic resonances, reflection off internal features produced by nonlinear dredging, and local, transient, gravitational instabilites within spiral arms in the generation of such features. Our simulations reinforce the idea that spiral structure in the gaseous component becomes increasingly flocculent and disordered with the passage of time, even when the background population of old disk stars is a grand-design spiral. We speculate that truly chaotic behavior arises when many overlapping ultraharmonic resonances develop in reaction to an imposed spiral forcing that has itself a nonlinear, yet smooth, wave profile.
description: Accepted for publication in Astrophysical Journal (tentatively October 10, 2003). Version with higher resolution embedded postscript figures at http://astron.berkeley.edu/~sukanya/ms.ps
Rotation of Early B-type Stars in the Large Magellanic Cloud - The role of evolution and metallicity
Creators: name: Keller, Stefan C.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: I present measurements of the projected rotational velocities of a sample of 100 early B-type main-sequence stars in the Large Magellanic Cloud. This is the first extragalactic study of the distribution of stellar rotational velocities. The sample is drawn from two sources: a sample derived from the vicinity of the main-sequence turnoff of young clusters (ages 1-3x10^7yrs), and a sample from the general field. I find the cluster population exhibits significantly more rapid rotation than that seen in the field. I have drawn analogous Galactic cluster and field samples from the literature. Comparison of these samples reveals the same effect. I propose the observed difference between cluster and field populations can be explained by a scenario of evolutionary enhancement of the surface angular momentum over the main-sequence lifetime. A comparison is made between the cluster and field populations of the LMC and the Galaxy in order to explore the effects of metallicity. This shows that the LMC stars are more rapid rotators than their Galactic counterparts.
description: 15 pages, PASA accepted
Dispersion of acoustic excitations in tetrahedral liquids
Creators: name: Fomin, Yu. D.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Investigation of the longitudinal and transverse excitations in liquids is of great importance for understanding the fundamentals of the liquid state of matter. One of the important questions is the temperature and density dependence of the frequency of the excitations. In our recent works it was shown that while in simple liquids the frequency of longitudinal excitations increases when the temperature is increased isochorically, in water the frequency can anomalously decrease with the temperature increase. In the present manuscript we study the dispersion curves of longitudinal and transverse excitations of water and liquid silicon modelled by Stillinger-Weber potential. We show that both substances demonstrate the anomaly of the dispersion curves, but it the case of water it is more pronounced.
An Off-lattice Model for Br Electrodeposition on Au(100): from DFT to Experiment
Creators: name: Mitchell, S. J.
name: Koper, M. T. M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Since Br adsorption on Au(100) displays an incommensurate ordered phase, a lattice-gas treatment of the adlayer configurations is not reliable. We therefore use density functional theory slab calculations to determine the parameters necessary for the construction of an off-lattice model. We compute and analyze the total energy and electron density as the lateral Br position and coverage are varied. This allows the calculation of the corrugation potential, the short-range lateral interactions, the dipole moment (long-range interactions), and the residence charge. From these parameters, we construct an off-lattice model with no freely adjustable parameters. The simulation results compare remarkably well with experimental results.
description: 42 pages, 15 embedded figures, submitted to Surface Science
Serum levels of bone sialoprotein correlate with portal pressure in patients with liver cirrhosis
Creators: name: Benz, Fabian
name: Bogen, Andreas
name: Praktiknjo, Michael
name: Jansen, Christian
name: Meyer, Carsten
name: Wree, Alexander
name: Demir, Muenevver
name: Loosen, Sven
name: Vucur, Mihael
name: Schierwagen, Robert
name: Tacke, Frank
name: Trebicka, Jonel
name: Roderburg, Christoph
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Biomarkers
subject: Disease Progression
subject: Hypertension, Portal
subject: Integrin-Binding Sialoprotein
subject: Liver Cirrhosis
subject: Portal Pressure
subject: Portal Vein
subject: Retrospective Studies
subject: Severity of Illness Index
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Liver cirrhosis represents the common end-stage of chronic liver diseases regardless of its etiology. Patients with compensated disease are mostly asymptomatic, however, progression to a decompensated disease stage is common. The available stratification strategies are often unsuitable to identify patients with a higher risk for disease progression and a limited prognosis. SIBLINGs, soluble glycophosphoproteins, are secreted into the blood by immune-cells. While osteopontin, the most prominent member of the SIBLINGs family, has been repeatedly associated with liver cirrhosis, data on the diagnostic and/or prognostic value of bone sialoprotein (BSP) are scarce and partly inconclusive. In this study, we analyzed the diagnostic and prognostic potential of circulating BSP in comparison to other standard laboratory markers in a large cohort of patients with liver cirrhosis receiving transjugular intrahepatic portosystemic shunt (TIPS). Serum levels of BSP were similar in patients with different disease stages and were not indicative for prognosis. Interestingly, BSP serum levels did correlate inversely with portal pressure, as well as its surrogates such as platelet count, the portal vein cross-sectional area and correlated positively with the portal venous velocity. In summary, our data highlight that BSP might represent a previously unrecognized marker for portal hypertension in patients with liver cirrhosis.
Simulating Kilonovae in the ΛCDM Universe
Creators: name: Jiang, Zhen
name: Wang, Jie
name: Zhang, Fenghui
name: Li, Li-Xin
name: Wang, Lan
name: Li, Ran
name: Gao, Liang
name: Han, Zhanwen
name: Pan, Jun
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Kilonovae are optical flashes produced in the aftermath of neutron star-neutron star mergers (NNMs) or neutron star-black hole mergers (NBMs). In this work, we use the Millennium Simulation, combined with a semi-analytic galaxy formation model--GABE (Galaxy Assembly with Binary Evolution) which adopts binary stellar population synthesis models, to explore the cosmic event rate of kilonovae, and the properties of their host galaxies in a cosmological context. We find that model with supernova kick velocity of 0 km/s fits the observation best, in agreement with the exception of some formation channels of binary neutron star. This indicates that NNMs prefer to originate from binary systems with low kick velocities. With V$_{\rm kick}$=0 km/s, the cosmic event rate of NNMs and NBMs at z=0 are 283 Gpc$^{-3}$yr$^{-1}$ and 91 Gpc$^{-3}$yr$^{-1}$, respectively, marginally consistent with the constraint from LVC GWTC-1. For Milky Way-mass galaxies, we predict the NNM rate is $25.7^{+59.6}_{-7.1}$ Myr$^{-1}$, which is also in good agreement with the observed properties of binary neutron stars in the Milky Way. Taking all the NNMs into account in the history of Milky Way-mass galaxies, we find that the averaged r-process elements yield with A>79 in a NNM and NBM event should be 0.01 M$_{\odot}$ to be consistent with observation. We conclude that NGC 4993, the host galaxy of GW170817, is a typical host galaxy for NNMs. However, generally NNMs and NBMs tend to reside in young, blue, star-forming, late-type galaxies, with stellar mass and gaseous metallicity distribution peaking at $10^{10.65}$ M$_{\odot}$ and 8.72-8.85, respectively. By studying kilonovae host galaxies in the cosmological background, it is promising to constrain model details better when we have more events in the forthcoming future. (abridged)
description: 13 pages, 11 figures, submitted to MNRAS
Sminthurus leucomelanus Nayrolles 1995
Creators: name: Thibaud, Jean-Marc
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Symphypleona
Sminthuridae
Sminthurus
Sminthurus leucomelanus

description: Sminthurus leucomelanus Nayrolles, 1995
Sminthurus leucomelanus Nayrolles, 1995b: 226.
DISTRIBUTION. — Pyrénées-Orientales. Laroque-des-Albères, pic de Neulos, 1250 m et Sorède, 450 m (Nayrolles 1995b).
description: Published as part of Thibaud, Jean-Marc, 2017, Catalogue des collemboles de France, pp. 297-436 in Zoosystema 39 (3) on page 408, DOI: 10.5252/z2017n3a1, http://zenodo.org/record/5496272