cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Theoretical and Logical Prerequisites for Legal Translation
Creators: name: Jopek-Bosiacka, Anna
Publisher: name: International Language and Law Association (ILLA)
Year: 2018
Subjects: subject: legal translation, legislative drafting guidelines, normative text, legal theory, logic, legislative style, legal culture, quality
subject: Social and Behavioral Sciences: Linguistics: Applied Linguistics; Arts and Humanities: Language Interpretation and Translation

description: The main research aim is to look at how formal principles of legal theory and logic across national jurisdictions affect translation of legislative texts. In the analyzed institutional legal context, official legislative drafting guidelines comprise the canon of good/quality legislation, universal and binding for each legal system. One of my research tasks is to juxtapose Polish legislative drafting guidelines with the European Union drafting guidelines, as well as with selected common law bill drafting manuals to see how certain parameters affect the way we process legislative texts in translation, and how different legal cultures influence the way we interpret legal texts. The qualitative analysis encompasses the legislative recommendations as to the formulation of legal definitions, the use of conjunctions, negation, and the grammatical category of aspect, mood and tense. Attempts are also made to search for any cross-cultural patterns of the analyzed parameters of normative texts. Thus, the comparison of normative texts between legal cultures, first, allows to observe that the legislative guidelines from various legal cultures differ with respect to the compared domains, and secondly, that these differences affect translated texts and the process of legal translation as such, as a result of the global processes of “Europeanization”, standardization, unification and hybridization of the national legal/legislative discourses. The results show that law, as a system of norms, always actualizes in a particular language and a particular culture. The national perspective in legal communication, which also contains many universal elements, conditions the quality assessment of legislative translation. A good legal translation is supposed to reproduce normative patterns vested in national legal culture and system.

Cite as: Jopek-Bosiacka, JLL 7 (2018), 47–69, DOI: 10.14762/jll.2018.047
description: International Journal of Language & Law (JLL), Vol 7: EU Legal Culture and Translation
Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy
Creators: name: Vaziri, Cyrus
name: Loeza, Silvia G. Herrera
name: Xu, Yi
name: Moffitt, Richard A.
name: Jin, Chong
name: Morrison, Ashley B.
name: Golitz, Brian T.
name: Yeh, Jen Jen
name: East, Michael P.
name: Peng, Xianlu L.
name: Graves, Lee M.
name: Lipner, Matthew B.
name: Johnson, Gary L.
name: Rashid, Naim U.
name: Gao, Yanzhe
Publisher: name: American Society for Clinical Investigation
Year: 2020

description: Over 55,000 people in the United States are diagnosed with pancreatic ductal adenocarcinoma (PDAC) yearly, and fewer than 20% of these patients survive a year beyond diagnosis. Chemotherapies are considered or used in nearly every PDAC case, but there is limited understanding of the complex signaling responses underlying resistance to these common treatments. Here, we take an unbiased approach to study protein kinase network changes following chemotherapies in patient-derived xenograft (PDX) models of PDAC to facilitate design of rational drug combinations. Proteomics profiling following chemotherapy regimens reveals that activation of JNK-JUN signaling occurs after 5-fluorouracil plus leucovorin (5-FU + LEU) and FOLFOX (5-FU + LEU plus oxaliplatin [OX]), but not after OX alone or gemcitabine. Cell and tumor growth assays with the irreversible inhibitor JNK-IN-8 and genetic manipulations demonstrate that JNK and JUN each contribute to chemoresistance and cancer cell survival after FOLFOX. Active JNK1 and JUN are specifically implicated in these effects, and synergy with JNK-IN-8 is linked to FOLFOX-mediated JUN activation, cell cycle dysregulation, and DNA damage response. This study highlights the potential for JNK-IN-8 as a biological tool and potential combination therapy with FOLFOX in PDAC and reinforces the need to tailor treatment to functional characteristics of individual tumors.
Legal Language and EU Integration. The Case of the Western Balkans
Creators: name: Čavoški, Aleksandra
Publisher: name: International Language and Law Association (ILLA)
Year: 2018
Subjects: subject: Western Balkans, EU integration, legal language and culture, neo-functionalism, legal translation, European Commission, sub-national technocrats
subject: Social and Behavioral Sciences: Linguistics: Applied Linguistics; Arts and Humanities: Language Interpretation and Translation

description: This paper investigates whether the Western Balkans, in particular four case study countries of the former Yugoslavia (Croatia, Serbia, Bosnia and Herzegovina, and Montenegro) can be seen as a particular region in terms of legal language and legal culture. By examining legal language and legal translation within the EU accession process, this paper argues that nation state formation and ethnic conflict had little impact on legal languages and cultures which remained very similar in these four countries after the break-up of Yugoslavia. Furthermore, through analysis based on neo-functionalist theory of EU integration, this paper explains how legal translation, though not a part of a deliberate EU enlargement strategy, becomes a vehicle of further EU integration as a result of political spill-over. It is particularly relevant in the case of the Western Balkans whereby both the European Commission and the sub-national bureaucracies make a full use of a common legal language and culture to their advantage to facilitate the accession process through the lens of legal translation. The paper concludes that the four countries of the Western Balkans can be viewed as a particular and unique region resulting from a shared legal language and culture which may have potential implications for the EU’s policy of multilingualism.

Cite as: Čavoški, JLL 7 (2018), 70–96, DOI: 10.14762/jll.2018.070
description: International Journal of Language & Law (JLL), Vol 7: EU Legal Culture and Translation
sj-docx-1-mrx-10.1177_01979183221139137 - Supplemental material for Does Time Since Arrival have an Effect on Immigrants’ Preferences for Vocational Education and Training Programs in Switzerland?
Creators: name: Bolli, Thomas
name: Rageth, Ladina
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-docx-1-mrx-10.1177_01979183221139137 for Does Time Since Arrival have an Effect on Immigrants’ Preferences for Vocational Education and Training Programs in Switzerland? by Thomas Bolli and Ladina Rageth in International Migration Review
EU Legal Language and Translation. Dehumanizing the Refugee Crisis
Creators: name: Loupaki, Elpida
Publisher: name: International Language and Law Association (ILLA)
Year: 2018
Subjects: subject: EU Legal Language; EU Translation; Migration; Dehumanizing Strategies; Corpus-based Methodology; Critical Discourse Analysis
subject: Social and Behavioral Sciences: Linguistics: Applied Linguistics; Arts and Humanities: Language Interpretation and Translation

description: The aim of this paper is to investigate lexical choices made in the EU legal texts, which could contribute to dehumanizing the “refugee crisis”, and compare them with the choices made by Greek translators. For this purpose, a corpus of EU legal texts, regulating migration matters and issued by the European Commission, is compiled. The language versions studied are English and Greek. The theoretical model adopted is Critical Discourse Analysis (CDA), and the major tools used are “framing” and “detachment techniques”. The methodology employed in this research is corpus-based and the analysis is both qualitative and quantitative. The English corpus studied revealed some convincing evidence about the existence of dehumanizing strategies in EU legal texts, and its Greek version is, as expected, totally in line with the original lexical choices. By analysing a number of characteristic examples, the present paper sheds some light on the multidimensional relationship between language and ideology, while examining its influence on the translation process.

Cite as: Loupaki, JLL 7 (2018), 97–116, DOI: 10.14762/jll.2018.097
description: International Journal of Language & Law (JLL), Vol 7: EU Legal Culture and Translation
PERFORMANCES DES SECTEURS DE L’AGRICULTURE ET DE L’INDUSTRIE MANUFACTURIERE AU MAROC: UNE EVALUATION PAR L’APPROCHE NON PARAMETRIQUE
Creators: name: AZEROUAL, Mohamed
name: DOUMI, Ali
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Agriculture, manufacturing industries, total factor productivity, productive performance, Malmquist index, Data Envelopment Analysis. JEL classification: C2, L00, Q10.

description: This article proposes a comparative analysis of productive performance in the Moroccan agricultural and manufacturing industries sector, over the period 1986-2012, using the Malmquist index. The obtained results show that the gain reached in terms of productivity in both sectors is mainly due to the improvement registered in the technical effectiveness rather than being due to the technological progression. Nevertheless, the total factors productivity (TFP) score in the agricultural sector is by far better than the TFP score in the industrial sector. Thus, the former sector exhibits important gains in terms of productivity with respect to the latter one. Furthermore, the contribution of sectorial productivities in the growth of the real Moroccan GDP generally remains very low in the studied period.
description: Revue Economie, Gestion et Société, No 7 (2016)
Tumor Necrosis Factor Alpha-Induced Interleukin-1 Alpha Synthesis and Cell Death Is Increased in Mouse Epithelial Cells Infected With Chlamydia muridarum
Creators: name: Ezzell, J Ashley
name: Harrell, Erin
name: Huntress, Ian
name: Gyorke, Clare E
name: Brochu, Hayden
name: Nagarajan, Uma M
name: Nagarajan, Shanmugam
name: Cho, Crescentia
name: Peng, Xinxia
Publisher: name: Oxford University Press (OUP)
Year: 2021

description: Chlamydia trachomatis-genital infection in women can be modeled in mice using Chlamydia muridarum. Using this model, it has been shown that the cytokines tumor necrosis factor (TNF)α and interleukin (IL)-1α lead to irreversible tissue damage in the oviducts. In this study, we investigated the contribution of TNFα on IL-1α synthesis in infected epithelial cells. We show that C muridarum infection enhanced TNFα-induced IL-1α expression and release in a mouse epithelial cell line. In addition to IL-1α, several TNFα-induced inflammatory genes were also highly induced, and infection enhanced TNF-induced cell death. In the mouse model of genital infection, oviducts from mice lacking the TNFα receptor displayed minimal staining for IL-1α compared with wild-type oviducts. Our results suggest TNFα and IL-1α enhance each other's downstream effects resulting in a hyperinflammatory response to chlamydial infection. We propose that biologics targeting TNF-induced IL-1α synthesis could be used to mitigate tissue damage during chlamydial infection.
Television Advertising and Health Insurance Marketplace Consumer Engagement in Kentucky: A Natural Experiment
Creators: name: Fowler, Erika Franklin
name: Shafer, Paul R
name: Baum, Laura
name: Gollust, Sarah E
Publisher: name: JMIR Publications
Year: 2018

description: BACKGROUND: Reductions in health insurance enrollment outreach could have negative effects on the individual health insurance market. Specifically, consumers may not be informed about the availability of coverage, and if some healthier consumers fail to enroll, there could be a worse risk pool for insurers. Kentucky created its own Marketplace, known as kynect, and adopted Medicaid expansion under the Affordable Care Act, which yielded the largest decline in adult uninsured rate in the United States from 2013 to 2016. The state sponsored an award-winning media campaign, yet after the election of a new governor in 2015, it declined to renew the television advertising contract for kynect and canceled all pending television ads with over a month remaining in the 2016 open enrollment period. OBJECTIVE: The objective of this study is to examine the stark variation in television advertising across multiple open enrollment periods in Kentucky and use this variation to estimate the dose-response effect of state-sponsored television advertising on consumer engagement with the Marketplace. In addition, we assess to what extent private insurers can potentially help fill the void when governments reduce or eliminate television advertising. METHODS: We obtained television advertising (Kantar Media/Campaign Media Analysis Group) and Marketplace data (Kentucky Health Benefit Exchange) for the period of October 1, 2013, through January 31, 2016, for Kentucky. Advertising data at the spot level were collapsed to state-week counts by sponsor type. Similarly, a state-week series of Marketplace engagement and enrollment measures were derived from state reports to Centers for Medicare and Medicaid Services. We used linear regression models to estimate associations between health insurance television advertising volume and measures of information-seeking (calls to call center; page views, visits, and unique visitors to the website) and enrollment (Web-based and total applications, Marketplace enrollment). RESULTS: We found significant dose-response effects of weekly state-sponsored television advertising volume during open enrollment on information-seeking behavior (marginal effects of an additional ad airing per week for website page views: 7973, visits: 390, and unique visitors: 388) and enrollment activity (applications, Web-based: 61 and total: 56). CONCLUSIONS: State-sponsored television advertising was associated with nearly 40% of unique visitors and Web-based applications. Insurance company television advertising was not a significant driver of engagement, an important consideration if cuts to government-sponsored advertising persist.
sj-pdf-1-smm-10.1177_09622802221146313 - Supplemental material for A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology
Creators: name: Hejazi, Nima S
name: Boileau, Philippe
name: van der Laan, Mark J
name: Hubbard, Alan E
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-smm-10.1177_09622802221146313 for A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology by Nima S Hejazi, Philippe Boileau, Mark J van der Laan and Alan E Hubbard in Statistical Methods in Medical Research
Additional file 1 of “Diving in the deep-end and swimming”: a mixed methods study using normalization process theory to evaluate a learning collaborative approach for the implementation of palliative care practices in hemodialysis centers
Creators: name: Holdsworth, Laura M.
name: Stedman, Margaret
name: Gustafsson, Erika Saliba
name: Han, Jialin
name: Asch, Steven M.
name: Harbert, Glenda
name: Lorenz, Karl A.
name: Lupu, Dale E.
name: Malcolm, Elizabeth
name: Moss, Alvin H.
name: Nicklas, Amanda
name: Kurella Tamura, Manjula
Publisher: name: figshare
Year: 2024
Subjects: Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 1.
Additional file 1 of Assessing oral health-related quality of life among older people in home-based care - survey results of the InSEMaP study in Germany
Creators: name: Koenig, Alena
name: Porzelt, Sarah
name: Behrens-Potratz, Anja
name: Stratmeyer, Peter
name: Schellhammer, Stefanie
name: Schmage, Petra
name: Konnopka, Claudia
name: Scherer, Martin
name: Konnopka, Alexander
name: Zimmermann, Thomas
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
sj-docx-1-vaw-10.1177_10778012221145302 - Supplemental material for Co-Occurring Intimate Partner Violence and Child Abuse in Eastern Democratic Republic of Congo: The Influence of Early Life Experiences of Abuse
Creators: name: Falb, Kathryn L.
name: Blackwell, Alexandra
name: Hategekimana, Jean de Dieu
name: Sifat, Munjireen
name: Roth, Danielle
name: O’Connor, Meghan
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-docx-1-vaw-10.1177_10778012221145302 for Co-Occurring Intimate Partner Violence and Child Abuse in Eastern Democratic Republic of Congo: The Influence of Early Life Experiences of Abuse by Kathryn L. Falb, Alexandra Blackwell, Jean de Dieu Hategekimana, Munjireen Sifat, Danielle Roth and Meghan O’Connor in Violence Against Women
Targeting Patient and Health System Barriers To Improve Rates of Hemodialysis Initiation with an Arteriovenous Access.
Creators: name: Narendra, Julia H
name: Peskoe, Sarah
name: Green, Jamie A
name: Flythe, Jennifer E
name: Yule, Christina
name: Lee, Shoou-Yih D
name: Boulware, L Ebony
name: Manivannan, Surya
name: Strigo, Tara S
name: Murphy, Shannon
name: Pendergast, Jane F
Publisher: name: Wolters Kluwer
Year: 2021

description: Background: Guidelines recommend pre-emptive creation of arteriovenous (AV) access. However, <20% of US patients initiate hemodialysis (HD) with a functional AV access. We implemented a quality improvement (QI) program to improve pre-HD vascular access care. Methods: After conducting qualitative research with key informants, we implemented a 7-month vascular access support QI program at Geisinger Health. The program targeted patient and health system barriers to AV access through education, needs assessment, peer support, care navigation, and electronic supports. We performed pre-, intra-, and postprogram stakeholder interviews to identify program barriers and facilitators and to assess acceptability. In a research substudy, we compared pre- and postprogram self-efficacy, knowledge, and confidence navigating vascular access care. Results: There were 37 patient and 32 clinician/personnel participants. Of the 37 patients, 34 (92%) completed vascular access-specific education, 33 (89%) underwent needs assessment, eight (22%) engaged with peer mentors, 21 (57%) had vein mapping, 18 (49%) had an initial surgical appointment, 15 (40%) underwent AV access surgery, and six (16%) started HD during the 7-month program. Qualitative findings demonstrated program acceptability to participants and suggested that education provision and emotional barrier identification were important to engaging patients in vascular access care. Research findings showed pre- to postprogram improvements in patient self-efficacy (28.1-30.8, P=0.05) and knowledge (4.9-6.9, P=0.004), and trends toward improvements in confidence among patients (8.0-8.7, P=0.2) and providers (7.5-7.8, P=0.1). Conclusions: Our intervention targeting patient and health system barriers improved patient vascular access knowledge and self-efficacy. Clinical Trial registry name and registration number: Breaking Down Care Process and Patient-level Barriers to Arteriovenous Access Creation Prior to Hemodialysis Initiation, NCT04032613.
title: Lavándula, Lavanda :
title: Directrices para la ejecución del examen de la distinción, la homogeneidad y la estabilidad.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Group identity.
Lavender
New Varieties of Plants

description: La finalidad de estas directrices (“directrices de examen”) es elaborar los principios que figuran en la Introducción General (documento TG/1/3) y sus documentos TGP conexos, con objeto de que sirvan de orientación práctica y detallada para el examen armonizado de la distinción, homogeneidad y estabilidad (DHE) y en particular, para identificar los caracteres apropiados para el examen DHE y producir descripciones armonizadas de variedades.
sj-docx-3-dhj-10.1177_20552076221144506 - Supplemental material for Impact of a digital health literacy intervention and risk predictors for multimorbidity among poor women of reproductive years: Results of a randomized-controlled trial
Creators: name: Jafree, Sara Rizvi
name: Muzammil, Anam
name: Burhan, Syeda Khadija
name: Bukhari, Nadia
name: Fischer, Florian
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111099 Nursing not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 111702 Aged Health Care
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies
subject: Anthropology
subject: FOS: Sociology
subject: 200299 Cultural Studies not elsewhere classified
subject: FOS: Other humanities
subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences
subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: Science Policy
subject: 160512 Social Policy
subject: FOS: Political science
subject: Sociology

description: Supplemental material, sj-docx-3-dhj-10.1177_20552076221144506 for Impact of a digital health literacy intervention and risk predictors for multimorbidity among poor women of reproductive years: Results of a randomized-controlled trial by Sara Rizvi Jafree, Anam Muzammil, Syeda Khadija Burhan, Nadia Bukhari and Florian Fischer in Digital Health
88299: The Cupboard
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Part of a Typescript of 'The Patchwork Flag', which included 38 examples of war and children's verses, with Robert Graves' manuscript corrections. Compiled with Nancy Nicholson. Sent also to Edward Marsh. Contains one two-sided leaf of a manuscript comments by Siegfried Sassoon, dated 21st August (1918)" Not published after Graves received criticism both from Sassoon And Robert Ross.
ACTOR: a latent Dirichlet model to compare expressed isoform proportions to a reference panel.
Creators: name: Love, Michael I
name: Nobel, Andrew B
name: McCabe, Sean D
Publisher: name: Oxford University Press (OUP)
Year: 2021

description: The relative proportion of RNA isoforms expressed for a given gene has been associated with disease states in cancer, retinal diseases, and neurological disorders. Examination of relative isoform proportions can help determine biological mechanisms, but such analyses often require a per-gene investigation of splicing patterns. Leveraging large public data sets produced by genomic consortia as a reference, one can compare splicing patterns in a data set of interest with those of a reference panel in which samples are divided into distinct groups, such as tissue of origin, or disease status. We propose A latent Dirichlet model to Compare expressed isoform proportions TO a Reference panel (ACTOR), a latent Dirichlet model with Dirichlet Multinomial observations to compare expressed isoform proportions in a data set to an independent reference panel. We use a variational Bayes procedure to estimate posterior distributions for the group membership of one or more samples. Using the Genotype-Tissue Expression project as a reference data set, we evaluate ACTOR on simulated and real RNA-seq data sets to determine tissue-type classifications of genes. ACTOR is publicly available as an R package at https://github.com/mccabes292/actor.
A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs
Creators: name: Love, Michael I
name: Robinson, Mark D
name: Hussain, Shobbir
name: Patro, Rob
name: Soneson, Charlotte
name: Malhotra, Dheeraj
Publisher: name: Life Science Alliance
Year: 2019

description: Most methods for statistical analysis of RNA-seq data take a matrix of abundance estimates for some type of genomic features as their input, and consequently the quality of any obtained results is directly dependent on the quality of these abundances. Here, we present the junction coverage compatibility score, which provides a way to evaluate the reliability of transcript-level abundance estimates and the accuracy of transcript annotation catalogs. It works by comparing the observed number of reads spanning each annotated splice junction in a genomic region to the predicted number of junction-spanning reads, inferred from the estimated transcript abundances and the genomic coordinates of the corresponding annotated transcripts. We show that although most genes show good agreement between the observed and predicted junction coverages, there is a small set of genes that do not. Genes with poor agreement are found regardless of the method used to estimate transcript abundances, and the corresponding transcript abundances should be treated with care in any downstream analyses.
sj-docx-1-dhj-10.1177_20552076221144181 - Supplemental material for Developing and testing an integrated patient mHealth and provider dashboard application system for type 2 diabetes management among Medicaid-enrolled pregnant individuals based on a user-centered approach: Mixed-methods study
Creators: name: Fareed, Naleef
name: Swoboda, Christine
name: Singh, Priti
name: Boettcher, Emma
name: Wang, Yiting
name: Venkatesh, Kartik
name: Strouse, Robert
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Nursing not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Aged Health Care
subject: Public Health and Health Services not elsewhere classified
subject: Engineering not elsewhere classified
subject: Anthropology
subject: FOS: Sociology
subject: Cultural Studies not elsewhere classified
subject: Information and Computing Sciences not elsewhere classified
subject: Organisation and Management Theory
subject: Science Policy
subject: Social Policy
subject: Sociology

description: Supplemental material, sj-docx-1-dhj-10.1177_20552076221144181 for Developing and testing an integrated patient mHealth and provider dashboard application system for type 2 diabetes management among Medicaid-enrolled pregnant individuals based on a user-centered approach: Mixed-methods study by Naleef Fareed, Christine Swoboda, Priti Singh, Emma Boettcher, Yiting Wang, Kartik Venkatesh and Robert Strouse in Digital Health
Nomenclature for kidney function and disease: executive summary and glossary from a Kidney Disease: Improving Global Outcomes (KDIGO) consensus conference*
Creators: name: Levey, Andrew S.
name: Eckardt, Kai-Uwe
name: Dorman, Nijsje M.
name: Christiansen, Stacy L.
name: Cheung, Michael
name: Jadoul, Michel
name: Winkelmayer, Wolfgang C.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: Nomenclature for kidney function and disease: executive summary and glossary from a Kidney Disease: Improving Global Outcomes (KDIGO) consensus conference*
LA NORME ISO 9001 DENATURE-T-ELLE LA STRUCTURE ORGANISATIONNELLE DES PME ?
Creators: name: LAAGUILI, Rachid
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: SMEs, Organizational Structure, ISO 9001, level changes, change of nature.

description: The literature review shows that the management system and organization of SMEs is specific. However, since the 90s, several studies question this thesis and highlight that SMEs can have big business features such as electronic data interchange, Just in time, quality certification, the capital risk, the export context, etc. Inspired by the distortion of current, we found that the requirements of ISO 9001 version 2008 standard are in contradiction with the organizational characteristics of SMEs. Thus, the objective of this paper is to answer the question: what is the ISO 9001: 2008 Can distort and undermine the organizational structure of SMEs?
description: Revue Economie, Gestion et Société, No 7 (2016)
A Reference Structure for Modular Model-based Analyses
Creators: name: Koch, Sandro Giovanni
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2024
Subjects: Interne Software Qualität
Software Architektur
Domänenspezifische Modellierungssprachen
Internal software quality
Software Architecture
Domain-specific modeling languages

description: In this work, the authors analysed the co-dependency between models and analyses, particularly the structure and interdependence of artefacts and the feature-based decomposition and composition of model-based analyses. Their goal is to improve the maintainability of model-based analyses. They have investigated the co-dependency of Domain-specific Modelling Languages (DSMLs) and model-based analyses regarding evolvability, understandability, and reusability.
An empirical Bayes approach for multiple tissue eQTL analysis
Creators: name: Wright, Fred A
name: Rusyn, Ivan
name: Shabalin, Andrey A
name: Nobel, Andrew B
name: Li, Gen
Publisher: name: Oxford University Press (OUP)
Year: 2017

description: Expression quantitative trait locus (eQTL) analyses identify genetic markers associated with the expression of a gene. Most up-to-date eQTL studies consider the connection between genetic variation and expression in a single tissue. Multi-tissue analyses have the potential to improve findings in a single tissue, and elucidate the genotypic basis of differences between tissues. In this article, we develop a hierarchical Bayesian model (MT-eQTL) for multi-tissue eQTL analysis. MT-eQTL explicitly captures patterns of variation in the presence or absence of eQTL, as well as the heterogeneity of effect sizes across tissues. We devise an efficient Expectation-Maximization (EM) algorithm for model fitting. Inferences concerning eQTL detection and the configuration of eQTL across tissues are derived from the adaptive thresholding of local false discovery rates, and maximum a posteriori estimation, respectively. We also provide theoretical justification of the adaptive procedure. We investigate the MT-eQTL model through an extensive analysis of a 9-tissue data set from the GTEx initiative.
Additional file 2 of Assessing oral health-related quality of life among older people in home-based care - survey results of the InSEMaP study in Germany
Creators: name: Koenig, Alena
name: Porzelt, Sarah
name: Behrens-Potratz, Anja
name: Stratmeyer, Peter
name: Schellhammer, Stefanie
name: Schmage, Petra
name: Konnopka, Claudia
name: Scherer, Martin
name: Konnopka, Alexander
name: Zimmermann, Thomas
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 2
Additional file 1 of “Diving in the deep-end and swimming”: a mixed methods study using normalization process theory to evaluate a learning collaborative approach for the implementation of palliative care practices in hemodialysis centers
Creators: name: Holdsworth, Laura M.
name: Stedman, Margaret
name: Gustafsson, Erika Saliba
name: Han, Jialin
name: Asch, Steven M.
name: Harbert, Glenda
name: Lorenz, Karl A.
name: Lupu, Dale E.
name: Malcolm, Elizabeth
name: Moss, Alvin H.
name: Nicklas, Amanda
name: Tamura, Manjula Kurella
Publisher: name: figshare
Year: 2023
Subjects: Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 1.
56016: Letter: To Edward Marsh
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Describes becoming reaccumulated to trench life after three months teaching in Le Havre / thanks Edward Marsh for sending a copy of Rupert Brooke's volume of prose 'Letters from America' / discusses his opinion of the book / appreciation of Samuel Butler and quotes from his poems / discusses Siegfried Sassoon's verse / friendship with Sassoon / situation at Verdun / quotes Shakespeare.
Effect of hypoxia-inducible factor-prolyl hydroxylase inhibitors on anemia in patients with CKD: a meta-analysis of randomized controlled trials including 2804 patients
Creators: name: Wang, Bin
name: Yin, Qing
name: Han, Yu-Chen
name: Wu, Min
name: Li, Zuo-Lin
name: Tu, Yan
name: Zhou, Le-ting
name: Wei, Qing
name: Liu, Hong
name: Tang, Ri-Ning
name: Cao, Jing-Yuan
name: Lv, Lin-Li
name: Liu, Bi-Cheng
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs) are orally active first-in-class new generation drugs for renal anemia. This extensive meta-analysis of randomized controlled trials (RCTs) was designed to provide clear information on the efficacy and safety of HIF-PHIs on anemia in chronic kidney disease (CKD) patients. Searches included PubMed, Web of Science, Ovid MEDLINE, and Cochrane Library database up to October 2019. RCTs of patients with CKD comparing HIF-PHIs with erythropoiesis-stimulating agents (ESAs) or placebo in the treatment of anemia. The primary outcome was hemoglobin change from baseline (Hb CFB); the secondary outcomes included iron-related parameters and the occurrence of each adverse event. 26 trials in 17 articles were included, with a total of 2804 dialysis or patients with CKD. HIF-PHIs treatment produced a significant beneficial effect on Hb CFB compared with the placebo group (MD, 0.69; 95% CI, 0.36 to 1.02). However, this favored effect of HIF-PHIs treatment was not observed in subgroup analysis among trials compared with ESAs (MD, 0.06; 95% CI, −0.20 to 0.31). The significant reduction in hepcidin by HIF-PHIs was observed in all subgroups when compared with the placebo group, whereas this effect was observed only in NDD-CKD patients when compared with ESAs. HIF-PHIs increased the risk of nausea (RR, 2.20; 95% CI, 1.06 to 4.53) and diarrhea (RR, 1.75; 95% CI, 1.06 to 2.92). We conclude that orally given HIF-PHIs are at least as efficacious as ESAs treatment to correct anemia short term in patients with CKD. In addition, HIF-PHIs improved iron metabolism and utilization in patients with CKD.
sj-docx-1-cnr-10.1177_10547738221090556 – Supplemental material for The Effect of Nursing Management of Patients Undergoing Interventional Therapy for Liver Cancer Compared with Standard Care on Patient-Reported Outcomes
Creators: name: Wang, Xiu-Bei
name: Sun, Ling-Fang
name: Niu, Mei-E
name: Cai, Jian-Zheng
name: Wang, Hai-Fang
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-cnr-10.1177_10547738221090556 for The Effect of Nursing Management of Patients Undergoing Interventional Therapy for Liver Cancer Compared with Standard Care on Patient-Reported Outcomes by Xiu-Bei Wang, Ling-Fang Sun, Mei-E Niu, Jian-Zheng Cai and Hai-Fang Wang in Clinical Nursing Research
L’ECONOMIE MAROCAINE : EVOLUTION AU PRISME DES THEORIES ECONOMIQUES DU DEVELOPPEMENT
Creators: name: KHALFAOUI, Abdelaziz
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Development economics, growth, economic theories, Morocco.

description: The Moroccan economy: analysis in the light of the economic development theories. The sustained growth of the Moroccan economy, registered during the last decade can leave hope for economic growth for the country and the beginning of improvement of living standards of its population classified as very poor development indicators. We have tried in this article to compare the development of the Moroccan economy since independence until 2014, with the pioneering development of theories, namely the theory of vicious circles of poverty Nurkse, the theory of dual economy of Lewis, the theory of economic retard of Rostow and the structuralist theory developed by Prebisch. This exercise revealed that the Moroccan economy, both complies with some features of these theories, but it stands out on other aspects. This finding corroborates the complexity of underdevelopment.
description: Revue Economie, Gestion et Société, No 7 (2016)
A Person-Centered Interdisciplinary Plan-of-Care Program for Dialysis: Implementation and Preliminary Testing
Creators: name: DeWalt, Darren A.
name: Flythe, Jennifer E.
name: Mold, James W.
name: Forfang, Derek
name: Dorough, Adeline
name: Kshirsagar, Abhijit V.
Publisher: name: Elsevier
Year: 2021

description: RATIONALE & OBJECTIVE: Despite growing interest in individualizing care, routine dialysis processes, including the interdisciplinary plan of care, often fail to account for patient-identified priorities. To better align dialysis care with patient priorities and improve care planning experiences, we implemented a person-centered care plan program at a single clinic. We also sought to gain insight into key implementation considerations and areas for program improvement. STUDY DESIGN: 6-month quality improvement project with research substudy. SETTING & PARTICIPANTS: 49 hemodialysis patients and 14 care team members at a North Carolina dialysis clinic. QUALITY IMPROVEMENT ACTIVITIES: Implementation of My Dialysis Plan, a person-centered care plan program. OUTCOMES: Participant perspectives and care plan meeting characteristics (quality improvement); pre- to postprogram change in patient-reported autonomy support, patient-centeredness of care, and dialysis care individualization (research). ANALYTICAL APPROACH: We used the Consolidated Framework for Implementation Research to guide implementation and evaluation. We conducted pre-, intra-, and post-project interviews with clinic stakeholders (patients, clinic personnel, and medical providers) to identify implementation barriers, facilitators, and perceptions. We compared pre- and post-project care plan meeting content and patient-reported outcome survey scores. RESULTS: We conducted 54 care plans with 49 patients. Overall, care teams successfully used My Dialysis Plan to elicit and link patient priorities to actionable aspects of dialysis care. Participants identified interdisciplinary team commitment, accountability, and the structured yet flexible meeting approach as key implementation elements. Throughout the project, stakeholder input guided program modifications (eg, implementation practices and resources) to better meet clinic needs, but follow-up on care plan-identified action items remained challenging. Among the 28 substudy participants, there was no difference in pre- to post-project patient-reported outcome survey scores. LIMITATIONS: Single clinic implementation. CONCLUSIONS: My Dialysis Plan has the potential to enhance dialysis care individualization and care plan experiences. Evaluation of program impact on patient-reported and clinical outcomes is needed.
sj-docx-1-jmq-10.1177_10776990221093930 – Supplemental material for Moderation Effects of Language Skills, Residential Tenure, and Education on Immigrants’ Learning From News
Creators: name: Medvedeva, Yulia S.
name: Leshner, Glenn M.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Education

description: Supplemental material, sj-docx-1-jmq-10.1177_10776990221093930 for Moderation Effects of Language Skills, Residential Tenure, and Education on Immigrants’ Learning From News by Yulia S. Medvedeva and Glenn M. Leshner in Journalism & Mass Communication Quarterly
ANALYSE CRITIQUE DES MODELES TERRITORIAUX D’INNOVATION, EN FRANCE, DEPUIS L’IMPLANTATION DES POLES DE COMPETITIVITE, JUSQU’A LA CREATION DES LIVINGS LABS
Creators: name: TCHEKEMIAN, Anthony
name: RICHARD, Guillaume
Publisher: name: Revue Economie, Gestion et Société
Year: 2016
Subjects: Clusters, competitive clusters, Living Lab, innovation, users.

description: This paper makes a critical analysis of the existence and evolution of territorial models of innovation in France from the implementation of competitiveness clusters, to the creation of Livings Labs. These approaches intend to boost the development of new innovative sectors as a support of a territory by creating synergy between the stakeholders. However, the Livings Labs, recently set up, allow people to invent new modes of exchange, public services and links between companies and the inhabitants of a territory, elements attributable to competitive clusters. The Livings Lab approach therefore acts as a connecting agent in helping to meet the new challenges of the territories, while placing users at the heart of the approach. Thus, unlike with clusters, within a Livings Lab users become co-designers, and co-producers of services they ultimately benefit themselves.
description: Revue Economie, Gestion et Société, No 7 (2016)
Designer proteins that competitively inhibit Gαq by targeting its effector site
Creators: name: Kuhlman, Brian
name: Endo-Streeter, Stuart
name: Sondek, John
name: Hussain, Mahmud
name: Cummins, Matthew C.
Publisher: name: Elsevier
Year: 2021

description: During signal transduction, the G protein, Gαq, binds and activates phospholipase C-β isozymes. Several diseases have been shown to manifest upon constitutively activating mutation of Gαq, such as uveal melanoma. Therefore, methods are needed to directly inhibit Gαq. Previously, we demonstrated that a peptide derived from a helix-turn-helix (HTH) region of PLC-β3 (residues 852-878) binds Gαq with low micromolar affinity and inhibits Gαq by competing with full-length PLC-β isozymes for binding. Since the HTH peptide is unstructured in the absence of Gαq, we hypothesized that embedding the HTH in a folded protein might stabilize the binding-competent conformation and further improve the potency of inhibition. Using the molecular modeling software Rosetta, we searched the Protein Data Bank for proteins with similar HTH structures near their surface. The candidate proteins were computationally docked against Gαq, and their surfaces were redesigned to stabilize this interaction. We then used yeast surface display to affinity mature the designs. The most potent design bound Gαq/i with high affinity in vitro (KD = 18 nM) and inhibited activation of PLC-β isozymes in HEK293 cells. We anticipate that our genetically encoded inhibitor will help interrogate the role of Gαq in healthy and disease model systems. Our work demonstrates that grafting interaction motifs into folded proteins is a powerful approach for generating inhibitors of protein-protein interactions.
Association between serum alkaline phosphatase and renal outcome in patients with type 2 diabetes mellitus
Creators: name: Zhao, Lijun
name: Li, Lin
name: Ren, Honghong
name: Zou, Yutong
name: Zhang, Rui
name: Wang, Shanshan
name: Xu, Huan
name: Zhang, Jie
name: Liu, Fang
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Marine Biology
Cancer
Science Policy
Computational Biology

description: This retrospective study included 299 patients with type 2 diabetes mellitus and biopsy-confirmed diabetic nephropathy (DN) to investigate the prognostic value of alkaline phosphatase (ALP) for renal outcome. Cox proportional hazards models were used to estimate the hazard ratios (HRs) for the serum ALP level on renal outcome, which was defined as end-stage renal disease (ESRD) or a 50% decline in estimated glomerular filtration rate (eGFR) from baseline. The median baseline ALP was 80 IU/L with an interquartile range of 64–97 IU/L. Serum ALP was negatively associated with eGFR but positively associated with proteinuria and renal interstitial fibrosis. During a median follow-up period of 23 months, ESRD or a 50% declined in the eGFR occurred in 156 (52.2%) patients. The highest quartile of ALP was significantly associated with poor renal outcome, as defined above (HR 2.38, 95% confidence interval [CI] 1.09–5.17), when adjusted for sociodemographics, baseline eGFR, proteinuria, liver function parameters, parathyroid hormone levels, and renal pathological findings. Each standard deviation higher in the natural log-transformed ALP was associated with a 25% increased risk for poor renal outcome. Additionally, there was a graded increase in the risk for poor renal outcome with higher ALP in patients with nephrotic-range proteinuria. However, no significant associations were observed between serum ALP levels and renal outcome in patients with non-nephrotic-range proteinuria. In conclusion, an elevated ALP level was independently associated with poor renal outcome in patients with type 2 diabetes mellitus and nephrotic-range proteinuria after multivariate adjustment.
66051: The Volunteer
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Manuscript in pen in Marion Scott's hand. After a manuscript from a letter of 29th August 1917 to Scott. Also found in the blue exercise book 52.5. The quotation in stanza 5 is from the American poet Walt Whitman's 'Passage to India'. Published in 'The Spectator' on 22nd February 1919. Included in 'War's Embers' (1919).