cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Edwards Group, surface and subsurface, central Texas
Creators: name: Rose, Peter R.
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1972
Subjects: subject: Geology, Stratigraphic -- Cretaceous

description: To obtain a print version of this publication visit: https://store.beg.utexas.edu/ and search for: RI0074. Accompanied by 11 foldout figures and plates -- Figure 9 : Generalized columnar section, Fredericksburg Division, Fashing-Person trend, south-central Texas. Figure 10 : Generalized columnar section, Washita Division, Fashing-Person trend, south-central Texas. Figure 14 : Isopachus map of Kainer Formation and equivalent rocks. Figure 15 : Isopachus map of Person Formation and equivalent rocks. Figure 16 : Isopachus map of Georgetown Formation and equivalent rocks. Figure 17 : Isopachus map of Del Rio Clay. Figure 18 : Isopachus map of Boda Limestone. Figure 22 : Generalized columnar section, Fort Terrett Formation, eastern Edwards Plateau, Central Texas. Figure 24 : Generalized columnar section, Segovia Formation, eastern Edwards Plateau, Central Texas. Plate 1 : Geologic Map of Eastern Edwards Plateau, Texas. Plate 2 : Regional Base Map, Edwards Group of Central Texas (Isopachus Contours on Edwards Group and Equivalent Rocks). Plate 3 : Subsurface Correlation Sections. Plate 4 : Stratigraphic Cross Sections
description: A thick sequence of Lower Cretaceous limestone and dolomite, known traditionally and informally as Edwards," covers much of west-central Texas and composes one of the dominant physiographic elements of the State, the Edwards Plateau. In this region the base of the Edwards is an important fresh-water aquifer. Along the inner edge of the Gulf Coastal Plain, in the Balcones fault zone, the Edwards is also exposed but severely faulted and altered by ground water. South and east of the Balcones fault zone these same rocks dip gently gulfward beneath the coastal plain. Here the Edwards is an important target for oil exploration, with nearly 400 million equivalent barrels of oil and gas located or produced to date. Stratigraphic relationships between the subsurface Edwards of this area and the Edwards of the eastern Edwards Plateau have never been securely established. The purposes of this report are (1) to delineate the stratigraphic framework of Edwards and associated rocks in the areas of the coastal plain and eastern Edwards Plateau; (2) to relate this framework with other work to the northeast and southwest; (3) to use the resulting regional framework to reconstruct a generalized paleogeography and depositional history of these rocks in Texas; and (4) to outline and explain the several diagenetic processes that have affected Edwards rocks.
Martiodrilus (Botaria) minor Zicsi 1998
Creators: name: Csuzdi, Csaba
name: Szederjesi, Tímea
name: Sherlock, Emma
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Haplotaxida
Glossoscolecidae
Martiodrilus
Martiodrilus minor

description: Martiodrilus (Botaria) minor Zicsi, 1998
Martiodrilus (Botaria) minor Zicsi, 1998b Opusc. Zool. (Budapest) 31: 156.
description: Published as part of Csuzdi, Csaba, Szederjesi, Tímea & Sherlock, Emma, 2018, Annotated checklist of earthworm species described by András Zicsi (Clitellata: Megadrili), pp. 11-42 in Zootaxa 4496 (1) on page 32, DOI: 10.11646/zootaxa.4496.1.4, http://zenodo.org/record/1447011
title: Palynology of the Eddleman coal (Pennsylvanian) of north-central Texas
Creators: name: Stone, J. Fred
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1969
Subjects: subject: Coal -- Geology -- Texas -- Young County
subject: Palynology -- Texas -- Young County

description: To obtain a print version of this publication visit: https://store.beg.utexas.edu/ and search for: RI0064. Part of illustrative matter in pocket.
description: The Eddleman Coal (Thrifty Formation, Cisco Group) in Young County, Texas, yielded a spore and pollen flora which was classified into 37 genera and 65 species. Ten species are regarded as new and are assigned to existing genera. A single new species is described and placed within a new genus. New taxa are named and described in accordance with the rules of the International Code of Botanical Nomenclature (1961). On the basis of the contained palynomorphs, the Eddleman Coal at the type locality is divisible into a lower and upper portion with the upper portion being distinguished by an increased abundance of the monosaccate genus Florinites. The chi-square test is used as a means of comparing samples from different localities. No statistically significant correlations are attainable between the samples tested. The flora substantiates the Virgilian age of the Eddleman Coal. The flora has 11 genera and 20 species in common with the microflora of the McLeansboro Group (Illinois Basin) as described by Kosanke (1950) and 22 genera and 18 species in common with the McLeansboro microflora as described by Peppers (1964). The Upper McLeansboro Group is in part Virgilian in age. The species Columinisporites pepperi Stone, sp. nov., Crassispora plicata, Calamospora pusilla, and Latipulvinites kosankii have been reported only from the Upper McLeansboro, and they are present in the Eddleman Coal.
MOESM4 of Virological response, HIV-1 drug resistance mutations and genetic diversity among patients on first-line antiretroviral therapy in Nâ  Djamena, Chad: findings from a cross-sectional study
Creators: name: ChattĂŠ Adawaye
name: Fokam, Joseph
name: Kamangu, Erick
name: Alio, Hamit
name: Aoudalkarim Chahad
name: Susin, Fabrice
name: Moussa, Ali
name: Tchombou Bertin
name: Abdelsalam Tidjani
name: Vaira, Dolores
name: Moutschen, Michel
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 4. Level of resistance to reverse transcriptase inhibitors. The table presents the proportion of patients with levels of genotypic susceptibility score following the Stanford algorithm.
Additional file 4: Table S4. of Analysis of medical service use of knee osteoarthritis and knee meniscal and ligament injuries in Korea: a cross-sectional study of national patient sample data
Creators: name: Suh, Chang
name: Lee, Yoon
name: Joon-Shik Shin
name: Jinho Lee
name: Me-Riong Kim
name: Wonil Koh
name: Yun-Yeop Cha
name: Byung-Cheul Shin
name: Eui-Hyoung Hwang
name: Suhr, Kristin
name: Kim, Mia
name: In-Hyuk Ha
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Narcotic medications in knee osteoarthritis and knee meniscal and ligament injury as assessed at the 5th Anatomical Therapeutic Chemical Classification System level. (DOCX 19 kb)
Borough of Lodi master plan, summary of proposals
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1964

description: The master plan of a community is intended as a basic guide to future development. The sum of its many parts, a combination of designs, programs and analyses, can be characterized as a "blueprint" for community action. This summary report represents an outline of the master plan for the Borough of Lodi. The development of the master plan is part of a process consisting of four basic elements:1. Community planning goals2. Backgroun.d for a planning program3. The master:plan and its implementation4. An action planning program
Martiodrilus (Botaria) minoriformis Zicsi 1998
Creators: name: Csuzdi, Csaba
name: Szederjesi, Tímea
name: Sherlock, Emma
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Haplotaxida
Glossoscolecidae
Martiodrilus
Martiodrilus minoriformis

description: Martiodrilus (Botaria) minoriformis Zicsi, 1998
Martiodrilus (Botaria) minoriformis Zicsi, 1998b Opusc. Zool. (Budapest) 31: 157.
description: Published as part of Csuzdi, Csaba, Szederjesi, Tímea & Sherlock, Emma, 2018, Annotated checklist of earthworm species described by András Zicsi (Clitellata: Megadrili), pp. 11-42 in Zootaxa 4496 (1) on page 32, DOI: 10.11646/zootaxa.4496.1.4, http://zenodo.org/record/1447011
Delaware Bay/Cape May coastal plain landscape habitat/land cover characterization project; final report
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1998

description: CRSSA has been involved in a project to map land cover and land cover change for the DelawareBay/Cape May region in southern New Jersey in cooperation with federal and state agencies. The overall goal of this project is to develop a standardized information base on the status of wildlife habitat in this landscape region and to track changes over the last twenty years. Using established Coastal Change Analysis Program (CCAP) protocols from  NOAA, the project sought to classify Landsat Thematic Mapper (TM) imagery to provide a baseline survey of coastal wetland and upland habitats. An earlier land cover classification product was expanded and 1994/1995 imagery was compared to earlier images from 19&2/19&3 and 1984 to map 20 years worth of land cover change.
Report of activities of the Civil Works Administration in Middlesex County, New Jersey (November 16, 1933 to March 31, 1934)
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1934

description: This report describes the history of the Civil Works Administration in Middlesex County, NJ and provides overviews of the projects undertaken between November 1933 and March 1934.
Middlesex Borough master plan : proposed land use plan
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1959

description: This report is the sixth in a series of studies preliminary to, and the basis for the final presentation of a Master Plan for Middlesex. The purpose of the Land Use Plan is to help establish a pattern of community development for the future through system of objectives in mapped form. The objectives may be summarized as follows: encouragement of development that results in a more 'balanced' community in terms of land uses; reservation of adequate areas for future types of development and enactment of controls to ensure separation of distinct uses; preservation of existing, desirable features; preservation of a suitable residential environment; maintenance of property values; throughfare development that has a minimal effect on existing residential areas; development of controls along Route 29; development of a 'municipal center' with basic governmental and cultural functions.
Preliminary master plan study report, Township of Maplewood, 1966
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1966

description: The purpose of this Master Plan review was to reappraise planning objectives in the light of changes that have occurred in Maplewood since 1949. Timely plans are necessary in order to continue the Township's high quality as a residential community. The following six objectives were identified for the Master Plan: 1. To maintain and improve the unique and desirable residential character of Maplewood. 2. To control and direct changes so as to better utilize land for residential purposes without unduly restricting variety. 3. To assign and develop suitable zones for business, industrial, and professional uses. 4. To provide healthful and serviceable recreational facilities for the community. 5. To maintain excellent education processes and to furnish adequate protective services and useful facilities. 6. To safeguard the future of our community by providing sufficient legal controls and enforcements to insure prudent usage and development.
Flood Plain information on the tidal lands of Cape May County, New Jersey
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1968

description: This report covers the tidal flood situation pertaining to the tidal lands of Cape May County, New Jersey. The report covers two significant phases of the Cape May County flood problem. It first brings together a record of the largest known floods on the Ocean and Bay sides of the county. Secondly, it covers probable future tidal floods: namely, the Intermediate Regional Tide and the Standard Project Tide. The report contains maps and profiles which indicate the extent of flooding that has been experienced and that might occur in the future in the area of study.
Methods for abatement of the pollution of the Raritan River : report to the Port Raritan District Commission
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1930

description: The Raritan River faces the destructive impact of pollution caused by the daily discharge into the stream of millions of gallons of raw sewage and industrial wastes. In order to abate the pollution and to maintain the Raritan River in a clean and sanitary condition, it is necessary to prevent the untreated sewage and industrial wastes from entering the river or else provide adequate and economical means of collection and conveyance to a definite point for disposal. The report offers five recommendations that pertain to the construction of treatment and disposal plants and the coordination of construction among local governments and industry.
Flood Plain information: Toms River, Union Branch, Ridgeway Branch and Long Swamp Creek, Ocean County, New Jersey
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1972

description: The portion of Ocean County covered by this report is subject to flooding from Toms River and its tributaries, Union Branch, Ridgeway Branch, and Long Swamp Creek. The properties along these streams are primarily residential and commercial and have been moderately damaged by floods of 1950, 1962 and 1968. The open spaces in the flood plains which may come under pressure for future development are extensive. Although large floods have occurred in the past, studies indicate that even larger floods are possible. This report has been prepared because a knowledge of flood potential and flood hazards is important in land use planning and for management decisions concerning floodplain utilization. It includes a history of flooding in Ocean County near Toms River and identifies those areas that are subject to possible future floods. Special emphasis is given to these floods through maps, photographs, profiles, and cross sections. The report does not provide solutions to flood problems; however, it does furnish a suitable basis for the adoption of land use controls to guide flood plain development and thereby prevent intensification of the loss problems.
Martiodrilus (Botaria) onorei Zicsi 1988
Creators: name: Csuzdi, Csaba
name: Szederjesi, Tímea
name: Sherlock, Emma
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Haplotaxida
Glossoscolecidae
Martiodrilus
Martiodrilus onorei

description: Martiodrilus (Botaria) onorei Zicsi, 1988
Martiodrilus onorei Zicsi, 1988c Acta Zool. Hung. 34 (4): 438.
Martiodrilus (Botaria) onorei: Zicsi 1998b Opusc. Zool. (Budapest) 31: 162.
description: Published as part of Csuzdi, Csaba, Szederjesi, Tímea & Sherlock, Emma, 2018, Annotated checklist of earthworm species described by András Zicsi (Clitellata: Megadrili), pp. 11-42 in Zootaxa 4496 (1) on page 32, DOI: 10.11646/zootaxa.4496.1.4, http://zenodo.org/record/1447011
title: Lignite resources in Texas
Creators: name: Kaiser, W. R.
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1980
Subjects: subject: Lignite -- Texas

description: To obtain a print version of this publication visit: https://store.beg.utexas.edu/ and search for: RI0104.
description: Texas lignite occurs in three Eocene (lower Tertiary) geologic units--the Wilcox Group, Jackson Group, and Yegua Formation--and in three ancient depositional systems--fluvial, deltaic, and strandplain/lagoonal. Near-surface resources in Texas at depths between 20 and 200 ft (6.1 and 61 m) in seams 3 ft (0.9 m) or thicker are 23,377 million short tons (21,208 million metric tons) and are dominantly fluvial in origin. More than 90 percent of the resources occur in the Wilcox and Jackson Groups north of the Colorado River. The size of individual deposits ranges from 50 to 500 million tons (45 to 450 million metric tons). The average seam thickness is less than 5 ft (1.5 m); a 10-ft (3.0-m) seam is exceptional. Depending on mining depth, reserves are estimated to be 8,635 to 11,102 million tons (7,834 to 10,072 million metric tons). Deep-basin resources at depths between 200 and 2,000 ft (61 and 610 m) in seams 5 ft (1.5 m) or thicker are 34,819 million tons (31,588 million metric tons), 70 and 30 percent being in the Wilcox and Jackson Groups, respectively. Approximately 2.4 million acres (1.0 million ha) are leased for lignite; 84, 12, and 4 percent of the acreage is in the Wilcox, Jackson, and Yegua, respectively. Wilcox lignite is the best grade, Yegua is intermediate, and Jackson is the poorest grade lignite in Texas. Typical Wilcox lignite has a heating value of 6,500 Btu/lb (3,612 kcal/kg) and a 33-percent moisture, 1-percent sulfur, and 15-percent ash content. Lignite reserves are adequate to meet the projected needs (6 to 7 billion short tons [5.4 to 6.3 billion metric tons]) of the electric utility and industrial sectors into the next century. Most of the lignite will continue to be used to generate electric power; however, lignite will be used in the future to produce synthetic fuels and chemicals.
Additional file 1: Figure S1. of Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets
Creators: name: Kanojia, Deepika
name: Garg, Manoj
name: Martinez, Jacqueline
name: Anand, M.T.
name: Luty, Samuel
name: Doan, Ngan
name: Said, Jonathan
name: Forscher, Charles
name: Tyner, Jeffrey
name: H. Koeffler
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Exogenous expression of kinase gene rescues the inhibition of proliferation. Table S1A. List of drugs and median IC50 values. Table S1B. Sequences of shRNA’s oligos and CRISPR sgRNA’s oligos. Table S1C. List of antibodies. Table S1D. Results of MTS proliferation assay using RNAi screening assay. (PDF 577 kb)
River Bend park master plan
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1987

description: The Atlantic County Department of Regional Planning and Development received a Coastal Planning grant in 1986 to develop a Recreation Master Plan for the River Bend site in Egg Harbor Township, New Jersey. This site is is part of a larger park system called The Great Egg Harbor Linear Park, Phase II. This report has been organized to first present an inventory of existing conditions on the site and an analysis of the site'ssuitability for recreational development. It also includes a chapter describing the program of uses for River Bend Park and a chapter that presents the Master Plan, the expression of the site's suitability and the development program translated into a design concept and its components including phasing.
title: Land and water resources, historical changes, and dune criticality : Mustang and North Padre Islands, Texas
Creators: name: White, William Allen, 1939-
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1978
Subjects: subject: Coasts -- Texas -- Mustang Island
subject: Coasts -- Texas -- Padre Island

description: To obtain a print version of this publication visit: https://store.beg.utexas.edu/ and search for: RI0092. Accompanied by 1 foldout plate -- Plate 1 : Land and water resources, Mustang and north Padre Islands, Texas
description: Barrier islands along the Texas Coastal Zone are part of a complex and dynamic system represented by many distinct yet interrelated environments affected by a variety of resources, natural processes, climatic conditions, and human activities. Because of the increasing realization that island resources are extremely important both as natural systems and as valuable recreational areas, the necessity of understanding their complexities and how man and his activities interact with them becomes more and more urgent. This report, which focuses on a 20-mile segment of barrier islands along the Texas coast, treats several aspects of the islands including land and water resources, active processes and natural hazards, historical changes in natural environments, historical changes in Gulf and bay shorelines, and the importance of fore-island dunes. A comprehensive understanding of these topics is important because essentially they govern the natural capability and limitations of barrier islands to support productive future development.
title: Depositional systems and shelf-slope relationships in Upper Pennsylvanian rocks, north-central Texas
Creators: name: Galloway, William E.
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1972
Subjects: subject: Geology -- Stratigraphic -- Pennsylvanian

description: To obtain a print version of this publication visit: https://store.beg.utexas.edu/ and search for: RI0075. Accompanied by 4 foldout plates -- Plate 1 : Sandstone isolith map, interval 1. Plate 2 : Sandstone isolith map, interval 2. Plate 3 : Sandstone isolith map, interval 3. Plate 4 : Geologic map of Upper Pennsylvanian rocks, north-central Texas
description: The Eastern Shelf was a constructional platform developed on the margin of the sediment-starved Midland Basin during Late Pennsylvanian and Early Permian time. A mixed terrigenous-carbonate sedimentary province characterized the shelf during most of its history. Sediments were derived from highlands to the east and northeast. Along the outcrop in Eastland, Stephens, Young, and Jack counties, uppermost Pennsylvanian beds comprise the Harpersville Formation, a boundary-defined rock stratigraphic unit within the Cisco Group. Harpersville facies extend westward into the subsurface 50 to 60 miles, where they grade into equivalent shelf margin carbonate and slope terrigenous facies. Preserved relief between the shelf margin and basin floor ranges from 600 to 1,100 feet with dips up to 5 degrees. Three component depositional systems, recognized on the basis of gross lithologic composition and position relative to the shelf edges, are the Cisco fluvial-deltaic system, the Sylvester shelf-edge bank system, and the Sweetwater slope system. The Cisco fluvial-deltaic system is composed of dipfed fluvial-deltaic facies and associated strike-fed interdeltaic embayment facies. Eight deltaic lobes have been mapped. The Sweetwater slope system is composed of several slope wedges, or fans, each of which includes shelf margin, slope trough, and distal slope sandstone facies, as well as slope mudstone facies. Terrigenous sediments were transported across the shelf by prograding fluvial-deltaic channels that locally extended through the Sylvester shelf-edge bank system and onto the slope where deposition in the deeper basin constructed submarine fans. The Eastern Shelf prograded into the Midland Basin through contemporaneous, local upbuilding by fluvial, deltaic, and shelf-edge bank deposition and outbuilding by slope-fan deposition. Sites of shelf construction or outbuilding shifted through time in response to sedimentary and structurally controlled abandonment of major delta lobes. Extrabasinal controls such as eustatic sea-level changes were of secondary importance in developing the depositional fabric of the shelf of the Harpersville Formation.
Additional file 1: of BugMat and FindNeighbour: command line and server applications for investigating bacterial relatedness
Creators: name: Mazariegos-Canellas, Oriol
name: Do, Trien
name: Peto, Tim
name: Eyre, David
name: Underwood, Anthony
name: Crook, Derrick
name: Wyllie, David
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Pseudocode for maintaining a variation model. (PDF 271 kb)
The Role of Matrix Metalloproteinase 13 in Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The normal breast contains many cell types, including milk-producing (epithelial) cells, fat cells and fibroblasts (stromal or supporting cells). Most research on breast cancer focuses on the genetic changes in the epithelial cells. However, the other cells in the breast tumor, although they are not cancer cells, also contribute to disease initiation, permissiveness, and progression. These non-epithelial cells respond to changes in the breast tissue microenvironment induced by the cancer cells. One recently identified difference between supporting, stromal cells in the normal breast and in breast cancer is the secretion of matrix metalloproteinase 13 (MMP-13), an extracellular matrix degrading enzyme. It is thought that cancer cells stimulate the stromal cells to make MMP-13, but it is not known how they do so and what the presence of MMP-13 contributes to breast cancer.

 Previous studies have demonstrated that MMP-13 is expressed by the non-cancerous cells in breast tumors that have migrated into the surrounding tissue. MMP-13 is not found in tumors that have not spread. Therefore, we hypothesize that MMP-13 is necessary for the events that make a breast tumor progress from a localized tumor (i.e., having a good clinical prognosis) to a tumor that has infiltrated the surrounding breast tissue (i.e., a less favorable clinical prognosis). Furthermore, we believe that cancer cells in early stage cancer stimulate supporting cells to make MMP-13.

 The only way to directly test if MMP-13 has a role in breast cancer is to perform animal experiments. We start with a mouse model in which the animals are genetically deficient in MMP-13. Then, we cross these MMP-13-deficient animals with mouse strains that express the rodent form of either the HER-2 oncogene, which is highly expressed in 30% of human breast cancers, or the WNT1 gene. These mice develop forms of breast cancer that resemble the human disease. If the hybrid crosses between the MMP-13-deficient and tumor producing strains develop either fewer breast tumors or fewer tumors that have spread to other organs, then we will better understand the role of MMP-13 in breast cancer. Finally, in other experiments we will demonstrate how MMP-13 is distributed in stromal cells adjacent to tumor cells, how MMP-13 is induced in stromal cells, and what proteins are degraded by MMP-13.

 Collectively, these animal studies will clarify the function of MMP-13 in breast cancer.
Issuance of leases for wind resource data collection on the Outer Continental Shelf offshore Delaware and New Jersey, environmental assessment
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2009

description: The report details a Finding of No Significant Impact for the environmental assessment regarding issuance of leases for wind resource data collection. Bluewater Wind is proposing to install two meteorological towers off the coast of Delaware and New Jersey to collect wind resource data needed to support development of offshore wind parks. Installation of each tower requires impact pile driving a single pile into the seafloor. No impacts to ESA-listed marine mammals are expected to occur due to implementation of mitigation and monitoring measures. However, pile driving will continue if non ESA-listed marine mammals are in the area; hence Level B harassment may occur to such species. Impacts are expected to be short term and include avoidance, masking, and interruption of behavioral activities (e.g., feeding) at time of exposure. The National Marine Fisheries Services (NMFS) is proposing to issue an Incidental Harassment Authorization (IHA) to permit incidental take of marine mammals pursuant to Section 1 01 (a)(5)(D) of the Marine Mammals Protection Act (MMPA).
ALDH Inhibitors as Novel Skin Depigmenting Agents
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Cutaneous hyperpigmentation is a highly prevalent clinical condition for which effective treatments are currently unavailable. While 4% of the worldwide population are affected by melasma (a hyperpigmentary disorder) and 90% of individuals over 60 have sun-induced hyperpigmentation, available topical treatments for these conditions are minimally effective, irritating, and cause cancer in laboratory animals. Therefore, new depigmenting agents with increased efficacy, decreased irritation, and decreased carcinogenicity would have a huge market share worldwide. Our group recently completed a genome-wide RNAi screen to identify novel drug targets for the rational design of topical lightening agents. These studies identified novel genes and pathways that regulate melanin production and identified aldehyde dehydrogenase inhibitors that can effectively inhibit pigment production in vitro. Subsequent studies from our group have determined that ALDH inhibitors inhibit tyrosinase expression and melanin accumulation in skin equivalent models that are FDA approved for efficacy testing. Several Aldh inhibitors are used in oral formulations for alcohol deterrence therapy in Europe, and abundant safety data is already available for these agents. While these studies provide convincing evidence that Aldh inhibitors are effective depigmenting agents that should have minimal toxicity, several pharmaceutical companies have indicated that skin sensitization studies and formulation optimization studies would be required before they would be willing to license this technology for commercial use. In this proposal, FDA-approved skin equivalent models will be used to define an optimal formulation of Aldh inhibitors for clinical application and determine the cytotoxicity and of this formulation to both keratinocytes and melanocytes. Established cytokine release assays will be utilized to determine whether these compounds induce irritation or inflammation in skin equivalents. Finally, skin sensitization studies in human subjects will be performed to ensure that these compounds do not induce irritation. Completion of these studies should facilitate the execution of a licensing agreement with one of the seven companies that have already expressed interest in this technology.
Oxygen Conserver Device for COPD Therapy
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: This project will advance UCSD’s existing patent pending oxygen conserver through a patient trial and FDA submission as a 510(k) medical device. The UCSD Conserver uses a novel approach for delivering supplemental oxygen (O2) to patients with low oxygen levels by measuring the instantaneous inhalation demand curve on a breath-by-breath basis and delivering an appropriate bolus of O2 to meet that demand. The UCSD Conserver is further augmented with pulse-oximetry feedback in order to optimize blood oxygen saturation (SpO2). The primary market for this device is the treatment of patients with chronic lung diseases [e.g., chronic obstructive pulmonary disease (COPD)]. Presently, the standard of care for COPD patients with low oxygen levels is supplemental oxygen therapy. Conserver devices are widely used to extend the useable life of oxygen cylinders, utilizing small pneumatic valve assemblies to meter out oxygen delivery based upon patient inhalations. Conventional O2 therapy uses continuous flow in dose levels ranging from 1.0 liter/min. to 6.0 liter/min. These flow rates are set manually in all state-of-the-art conservers and though they will pulse oxygen faster with increasing respiratory rate, they do not adjust pulse volume to address the depth of a patient’s inhalation (a deep breath will give more oxygen as compared to many short fast breaths). Inhalation depth vs. rate is a more accurate measure of oxygen demand as one experiences change in exertion level; therefore, providing oxygen early and at greater volumes during the inhalation cycle will give a patient a higher blood oxygen saturation (SpO2) level. As such, the standard-of-care conserver does not adjust to changing levels of physical activity in a patient and therefore limits them to more sedentary activities and a reduced quality of life. There is also considerable variation in the amount of oxygen delivered by current conserver devices at similar settings and the oxygen dose is not adjusted to the patient’s oxygen level, a major limitation to this type of treatment. The UCSD Conserver overcomes these limitations and allows a patient’s oxygen delivery to be adjusted in real-time, automatically, improving a patient’s oxygen level and ability to remain active in normal daily activities. These advantages will directly improve the quality of life for patients with chronic lung diseases.
Environmental resource inventory, a report prepared for Bass River Township
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1974

description: The· Natural Resources Inventory was initiated by the Environmental Commission with the development of maps of the types and characteristics of natural resources associated with the water, land, soil, vegetation and wildlife. The maps, with abundant pertinent information are now available for guidance and use by the governing body of the Township and its Planning Board in the task of developing the Master Plan for Bass River Township.
Martiodrilus (Botaria) parvus Zicsi 1998
Creators: name: Csuzdi, Csaba
name: Szederjesi, Tímea
name: Sherlock, Emma
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Clitellata
Haplotaxida
Glossoscolecidae
Martiodrilus
Martiodrilus parvus

description: Martiodrilus (Botaria) parvus Zicsi, 1998
Martiodrilus (Botaria) parvus Zicsi, 1998b Opusc. Zool. (Budapest) 31: 160.
description: Published as part of Csuzdi, Csaba, Szederjesi, Tímea & Sherlock, Emma, 2018, Annotated checklist of earthworm species described by András Zicsi (Clitellata: Megadrili), pp. 11-42 in Zootaxa 4496 (1) on page 32, DOI: 10.11646/zootaxa.4496.1.4, http://zenodo.org/record/1447011
JIYDADOSHLAR OILASINING ASOSIY TURKUM VA TURLARI. TARQALISHI VA AHAMIYATI
Creators: name: Abdusamatova, Gulhayo
Publisher: name: Zenodo
Year: 2024

description: ushbu tezisda jiydadoshlar oilasi tarqalishi asosiy turkumlari, meva tarkibi, gulining tuzulishi haqida umumiy ma’lumotlar berilgan.
Recovering from Superstorm Sandy: rebuilding our infrastructure. Hearing before the Subcommittee on Housing, Transportation and Community Development of the Committee on Banking, Housing, and Urban Affairs.
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2013

description: This document includes transcription of testimony given and statements made at the public hearing held on December 20, 2012 by representatives of federal and state agencies, among them the Federal Transit Administration, Department of Housing and Urban Development, NJ Transit, Metropolitan Transit Authority, and the Port Authority of New York and New Jersey.
Formulated Quality Assurance (QA) and Customer Satisfaction (CSAT) Scorecards Indexing and inference research information from the Business Process Outsource (BPO) Workplace
Creators: name: Lee, Christopher M.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460901
subject: Business process management
classificationCode: 350715
subject: Quality management
classificationCode: 350712
subject: Production and operations management
classificationCode: 350301
subject: Business analytics

description: Business Process Outsource (BPO) emerged as one of the successful companies in the Philippines more than twenty years ago. It was way back then but still considered to be one of the backbone income generated resources in the country. The research investigation merely discussed on Quality Assurance (QA) and Customer Satisfaction (CSAT) score cards give us inference research information that have been generated to all service agents, and how this KPIs index metrics maintains its stability by every BPO employers in the community. It also explains how the company runs their operative and resource management by using these BPO metrics to facilitate their business development metrics and evaluations towards call center employees. This research study will serve to any future developmental research goals relative to business strategy planning and other contact center outsourcing practices.
Astrocyte pattern - Crochet pattern
Creators: name: Adams, Eleanor
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Research Support
subject: Research Support

description: The pattern for one of the neurone models in the "Hello Brain!" public exhibition at the Francis Crick Institute in 2024. The Crick commissioned the creation of this model and the writing of this pattern.
Optical Device for intra-operative delineation of tumor margins
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: This application is to construct a robust clinical tool (compliant with regulatory requirements) for real-time assessment of tissue during surgical resection or stereotaxic biopsy in patients. During interventional procedures it is important to rapidly distinguish between cancer and surrounding healthy tissue. Finding the optimal balance between adequate tissue resection (minimizing recurrence) and organ preservation (minimizing functional damage) is the mainstay of surgical oncology. The proposed optical device has the potential to assist surgeons or treating physicians in achieving that goal. The device is based on time-resolved fluorescence measurement of endogenous tissue fluorescence (autofluorescence). This device can be used as stand-alone diagnostic tool or for improving the functionality of current technologies used during clinical interventions (e.g. needle biopsy probes and endoscopes or laparoscopes). The device is envisioned to improve the accuracy of surgical resection of tumors, in treatment decision, and in the guidance of stereotaxic biopsy and minimization of sampling error. The proposed work builds-up on our preliminary fluorescence studies of brain tumors and head and neck cancer that demonstrate that tumor vs normal tissue exhibit distinct time-resolved fluorescence emission features. Initially the device will be tailored to intraoperative delineation of brain tumors. It should be noted, however, that the proposed technique can be developed as a platform technology which can be adapted to nearly all cancer surgeries and to stereotaxic procedures outside the central nervous system. There are no effective tools for real-time assessment of brain tissue during neurosurgical interventions or stereotaxic biopsies. Currently, accurate histopathologic diagnosis at the time of surgery relies on frozen tissue analysis, which is time consuming, prone to inaccuracy, and at risk of sampling error because the limited number of biopsy specimens may misrepresent tumor composition. Moreover, brain biopsies are performed via craniotomy or through a burr hole using stereotaxic techniques. Often, multiple biopsy samples are needed before pathologic tissue is encountered and confirmed by the pathologist, resulting in sampling error and risk to the patient. Thus, the ability to optically query tissue prior to removal is of immense potential clinical benefit. If successful, this work will (i) enhance the ability of surgeons to distinguish tumor from normal brain tissue intraoperatively, (ii) improve the specificity and sensitivity of diagnostic and reduce the number of in biopsies, (iii) reduce the duration of surgical procedures and the need for subsequent surgeries, (iv) increase the opportunity for complete resection of tumors and decrease the risk of resection of normal tissue.
THE IMPACT OF EXTERNAL AUDITS ON FINANCIAL ACCOUNTABILITY IN RWANDAN HOSPITALS
Creators: name: 1Kwame Mensah, 2Mbonigaba Celestin &3Youssef El Mansouri, 4Liam Anderson
Publisher: name: Zenodo
Year: 2013

description: This study evaluates the impact of external audits on financial accountability in Rwandan hospitals between 2008 and 2012. Employing a descriptive research design, it integrates quantitative data from financial records and qualitative insights from interviews. Results indicate a significant improvement in financial accountability metrics, including a 52% reduction in financial discrepancies per hospital (from RWF 10,000,000 in 2008 to RWF 666,667 in 2012, p < 0.01) and a 15% increase in compliance rates post-audit. Audit coverage rose from 37.5% in 2008 to 90% in 2012, reflecting improved implementation. However, challenges such as insufficient training persisted, escalating from 30% in 2008 to 70% in 2012. Recommendations include capacity-building programs, enhanced follow-up mechanisms, and integration of financial management technology. These measures aim to sustain accountability improvements and address emerging challenges.
Fish, megainvertebrates, and associated hydrographic observations collected in Newark Bay, New Jersey, during May 1993 - April 1994
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1997

description: Summary tabulations and illustrations for 56 species representing 37 families of fish and megainvertebrates as well as associated environmental observations are given for 299 8.5-motter trawl tows, 105 4.9-m otter trawl tows, and 92 experimental gill net sets occupied in Newark Bay, New Jersey from May 1993 to April 1994.
Heilige Evangelium des Iohannes, syrisch, in Harklensischer Uebersetzung
Creators: name: Bernstein, Georg Heinrich
Publisher: name: No Publisher Supplied
Year: 1853

description: Produced in the early seventh century near Alexandria, the Harklean version is the last in a line of Syriac New Testament versions (or parts thereof). This volume presents a meticulously detailed edition of the Gospel of John in the Harklean version according to Vatican Syriac Manuscript 2&1. The Syriac text is fully marked with vowels and other diacritical marks. Bernstein provides a lengthy introduction in which he discusses these vowels and other orthographic data from the manuscript. Several pages of critical remarks to the Syriac text, which touch on both other Syriac manuscripts and the Greek text are also included. This volume will be of definite interest to biblical scholars conversant Syriac and other scholars of the Syriac language.
Diagnosing Endometriosis by Endometrial Biopsy
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Endometriosis affects 10% of reproductive-age women and 50% with pain and infertility. It is a major public health issue and healthcare cost ($69.4B in 2009 in the US). The gold standard to diagnose endometriosis is surgical exploration and staging of the disease in a hospital setting under general anesthesia. Average time to diagnosis from symptom onset is 11.7 years. To shorten time to diagnosis, reduce invasiveness/risks of the diagnostic method, and optimize therapeutic decision-making, biomarkers in the endometrium (lining of the uterus, obtained by office biopsy) or in blood are being explored. We have IP on the biopsy approach. Using whole genome arrays, we found differential expression of select genes in endometrium of women with vs. without disease and have 2 patents assigned to the UC Regents (“Methods of Diagnosing Endometriosis”, Giudice, Inventor; No.7,871,778 issued 01/18/11; No.8,247,174 issued 08/21/12) based on our findings. We used margin tree classification and resampling analyses to develop a disease/severity diagnostic classifier with a sizeable (n>100) set of meticulously annotated clinical endometrial tissue samples and have 4 main findings: the endometrial transcriptome is altered in the presence of endometriosis and when non-endometrial uterine pathologies (e.g. fibroids) are present, such that classifier analysis can discriminate if these pathologies are entirely absent or one or more of them is present (e.g., in patients with pelvic pain); best performing classifiers diagnose samples from specific menstrual cycle phases; composite classifiers diagnose endometriosis disease and severity (stage) with >90% accuracy; and classifiers determine disease/severity based on small numbers of genes, which are high value candidates to develop diagnostic/biomarker/therapeutic targets. The margin tree classification utilizes sequential binary decisions each based on specific genes that are distinct for different decision nodes and classifiers. Within a classifier family, core genes are present in each decision node and are thus indispensible for diagnosis at the defined accuracy. The next steps and intent of this application are to validate core genes at the decision points in the highest performance classifiers and validate the classifiers in prospectively obtained, existing endometrial tissue from 27 women with chronic pelvic pain who underwent surgery and identification of disease/stage/no disease – outcomes to which we are blinded.
Additional file 1: Appendix A of Measurement properties of comorbidity indices in maternal health research: a systematic review
Creators: name: Aoyama, Kazuyoshi
name: DâSouza, Rohan
name: Inada, Eiichi
name: Lapinsky, Stephen
name: Fowler, Robert
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: Computational Biology

description: Search strategy in MEDLINE, EMBASE. Detailed search strategy we used in MEDLINE and EMBASE. Appendix B Weighted conditions of the Maternal Comorbidity Index. Detailed description of the Maternal Comorbidity Index. Appendix C Weighted conditions of the Charlson Comorbidity Index. Detailed description of the Charlson Comorbidity Index. Appendix D List of comorbidities in the Elixhauser Comorbidity Index. Detailed description of comorbidities in the Elixhauser Comorbidity Index. (PDF 58 kb)