cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Numerical Solution of Linear Ordinary Differential Equations and Differential-Algebraic Equations by Spectral Methods
Creators: name: Saravi, Masoud
Publisher: name: The Open University
Year: 2008

description: This thesis involves the implementation of spectral methods, for numerical solution of linear Ordinary Differential Equations (ODEs) and linear Differential-Algebraic Equations (DAEs). First we consider ODEs with some ordinary problems, and then, focus on those problems in which the solution function or some coefficient functions have singularities. Then, by expressing weak and strong aspects of spectral methods to solve these kinds of problems, a modified pseudo-spectral method which is more efficient than other spectral methods is suggested and tested on some examples. We extend the pseudo-spectral method to solve a system of linear ODEs and linear DAEs and compare this method with other methods such as Backward Difference Formulae (BDF), and implicit Runge-Kutta (RK) methods using some numerical examples. Furthermore, by using appropriate choice of Gauss-Chebyshev-Radau points, we will show that this method can be used to solve a linear DAE whenever some of coefficient functions have singularities by providing some examples. We also used some problems that have already been considered by some authors by finite difference methods, and compare their results with ours. Finally, we present a short survey of properties and numerical methods for solving DAE problems and then we extend the pseudo-spectral method to solve DAE problems with variable coefficient functions. Our numerical experience shows that spectral and pseudo-spectral methods and their modified versions are very promising for linear ODE and linear DAE problems with solution or coefficient functions having singularities. In section 3.2, a modified method for solving an ODE is introduced which is new work. Furthermore, an extension of this method for solving a DAE or system of ODEs which has been explained in section 4.6 of chapter four is also a new idea and has not been done by anyone previously. In all chapters, wherever we talk about ODE or DAE we mean linear.
Reaching the last 10 percent out of school children: the role of AIDS
Creators: name: Okumu, Ibrahim Mike
name: Mugisha, Frederick
name: Okumu, Ibrahim Mike
name: Mugisha, Frederick
Publisher: name: Unknown
Year: 2016
Subjects: subject: Health Economics and Policy
subject: Teaching/Communication/Extension/Profession
subject: AIDS
subject: Children
subject: School
subject: logit
subject: Uganda

description: This paper investigates the role of AIDS on children being out of school. Put differently, whether it is because of AIDS that children are out of school. The main data source was the Northern Uganda Survey of 2004 conducted by Uganda Bureau of Statistics (UBOS) between July and December 2004. The survey was meant to provide indicators to guide the monitoring and evaluation function of the NUSAF project period in 18 districts of Northern Uganda. We defined and identified ‘aids affected households’, used descriptive analysis as well as a multinomial specification. We further explored the role of poverty using changes in household asset value between 1992 and 2004. There is no conclusive evidence that children are out of school due to AIDS. AIDS has a marginal effect on children failing to continue in school but this is not statistically significant. However there is strong evidence that children are out of school because of a decline in household asset value. To reach children who have never attended school, rather than focusing on ‘AIDS affected households’, a much greater impact is expected from preventing major decline in ‘household asset value’.
Continuous vs. discrete models for the quantum harmonic oscillator and the hydrogen atom
Creators: name: Lorente, M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Kravchuk and Meixner polynomials of discrete variable are introduced for the discrete models of the harmonic oscillator and hydrogen atom. Starting from Rodrigues formula we construct raising and lowering operators, commutation and anticommutation relations. The physical properties of discrete models are figured out through the equivalence with the continuous models obtained by limit process.
description: LaTeX, 14 pages (late submission)
5545: James Charles Robertson, recipient of the Meritorious Service Medal
Creators: name: Project Team, Lest We Forget
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: James Charles Robertson was an uncle. He was son of George Robertson and Jessie Robertson (née Carnie). He was born on 24/11/1884 at Midmill, Kintore, Scotland. He was the second James Charles Robertson in the family. The first accidentally drowned in the mill lade at Midmill, Kintore, in June 1882 aged 18 months. James Charles Robertson was an apprentice watchmaker at Ellon in 1901. He married Helen Jane Rose Leslie, daughter of James Leslie and Catherine Smith Leslie. His brothers, William Alexander Robertson and John Cameron Robertson, and cousins William James Carnie and John Carnie all served in the armed services in the First World War.James Charles Robertson enlisted in the Royal Flying Corps on 19/05/1916. He was in the Royal Air Force when this was set up. His service number was 28924. He was an aircraft fitter with rank up to sergeant. Some of his photographs show a Sopwith Camel which served with 28 Squadron. In November 1917 that unit left the Western Front for Italy. He was, however, definitely located at San Pietro In Gu, Veneto, Italy, which suggests that he was with 7th Aircraft Park, recovering and repairing wrecks. He did serve in H Flight, 66 Squadron in Italy and the middle East. He was awarded the Meritorious Service Medal.On 13/07/1919 he was transferred to the reserve. He lived at Cricklewood, London. His occupation was watchmaker and jeweller. He died on 09/11/1972 at Highgate Hospital, London.
Inferring Mycobacterium bovis transmission between cattle and badgers using isolates from the Randomised Badger Culling Trial.
Creators: name: Van Tonder, Andries
name: Thornton, Mark J
name: Conlan, Andrew
name: Jolley, Keith A
name: Goolding, Lee
name: Mitchell, Andrew P
name: Dale, James
name: Palkopoulou, Eleftheria
name: Hogarth, Philip J
name: Hewinson, R Glyn
name: Wood, James
name: Parkhill, Julian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: subject: Research Article
subject: Biology and life sciences
subject: Computer and information sciences
subject: FOS: Computer and information sciences

description: Mycobacterium bovis (M. bovis) is a causative agent of bovine tuberculosis, a significant source of morbidity and mortality in the global cattle industry. The Randomised Badger Culling Trial was a field experiment carried out between 1998 and 2005 in the South West of England. As part of this trial, M. bovis isolates were collected from contemporaneous and overlapping populations of badgers and cattle within ten defined trial areas. We combined whole genome sequences from 1,442 isolates with location and cattle movement data, identifying transmission clusters and inferred rates and routes of transmission of M. bovis. Most trial areas contained a single transmission cluster that had been established shortly before sampling, often contemporaneous with the expansion of bovine tuberculosis in the 1980s. The estimated rate of transmission from badger to cattle was approximately two times higher than from cattle to badger, and the rate of within-species transmission considerably exceeded these for both species. We identified long distance transmission events linked to cattle movement, recurrence of herd breakdown by infection within the same transmission clusters and superspreader events driven by cattle but not badgers. Overall, our data suggests that the transmission clusters in different parts of South West England that are still evident today were established by long-distance seeding events involving cattle movement, not by recrudescence from a long-established wildlife reservoir. Clusters are maintained primarily by within-species transmission, with less frequent spill-over both from badger to cattle and cattle to badger.
Microcredit in Uganda: Fundamental Reform or Just another Neoliberal Policy?
Creators: name: Miller, Paige
name: Brux, Jacqueline Murray
name: Neema, Clementia Murembe
name: Miller, Paige
name: Brux, Jacqueline Murray
name: Neema, Clementia Murembe
Publisher: name: Unknown
Year: 2016
Subjects: subject: Financial Economics
subject: Labor and Human Capital
subject: Gender
subject: Microcredit
subject: Africa
subject: Development
subject: Neoliberalism
subject: Poverty

description: Widespread global initiatives aimed at improving conditions for the world’s poor have frequently begun with the vision of just a few people. Examples are numerous but in this paper we focus on micro-enterprise credit (microcredit). In the case of microcredit, a widespread movement has placed projects in many countries throughout the developing world. Microcredit is typically made available to women who would otherwise not have access to loans on reasonable terms. While some view microcredit as a revolutionary means of improving both the lives of women and the poor more generally, others argue it is a band aid approach to development, rooted in a neoliberal logic that does very little in terms of enacting real, long-term change. These arguments, however, are often based on evidence from Asian or other non-African countries and so don’t account for different models of microcredit or cultural context in shaping outcomes for women and their families. We address these issues through a qualitative study of three microcredit groups in the east African country of Uganda. Based on qualitative interviews, we argue that microcredit holds a number of possibilities for women and their communities including healthier families and educated children as well as more intangible benefits such as feelings of solidarity and self-confidence. While our interviews suggest a number of benefits of micro-enterprise credit, we recognize that such programs are not the single solution to poverty. Ultimately, though, we argue that the negatives do not dispel the benefits that can result for many women.
On rising magnetic flux tube and formation of sunspots in a deep domain
Creators: name: Hotta, H.
name: Iijima, H.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We investigate the rising flux tube and the formation of sunspots in an unprecedentedly deep computational domain that covers the whole convection zone with a radiative magnetohydrodynamics simulation. Previous calculations had shallow computational boxes (< 30 Mm) and convection zones at a depth of 200 Mm. By using our new numerical code R2D2, we succeed in covering the whole convection zone and reproduce the formation of the sunspot from a simple horizontal flux tube because of the turbulent thermal convection. The main findings are (1) The rising speed of the flux tube is larger than the upward convection velocity because of the low density caused by the magnetic pressure and the suppression of the mixing. (2) The rising speed of the flux tube exceeds 250 m/s at a depth of 18 Mm, while we do not see any clear evidence of the divergent flow 3 hr before the emergence at the solar surface. (3) Initially, the root of the flux tube is filled with the downflows and then the upflow fills the center of the flux tube during the formation of the sunspot. (4) The essential mechanisms for the formation of the sunspot are the coherent inflow and the turbulent transport. (5) The low-temperature region is extended to a depth of at least 40 Mm in the matured sunspot, with the high-temperature region in the center of the flux tube. Some of the findings indicate the importance of the deep computational domain for the flux emergence simulations.
description: 17 pages, 24 figures. Accepted for publication by MNRAS
Determinants of Inclusive Growth in Africa: Role of Health and Demographic Changes
Creators: name: Tella, Sherriffdeen A.
name: Alimi, Olorunfemi Y.
name: Tella, Sherriffdeen A.
name: Alimi, Olorunfemi Y.
Publisher: name: Unknown
Year: 2016
Subjects: subject: Health Economics and Policy
subject: health
subject: population
subject: pro-poor growth
subject: Africa

description: This paper examines the role of health and population growth on inclusive growth in selected 14 African countries from 1995 to 2012. Using the Fixed effect method, the findings indicate that finances from the health sector have greater impact towards the inclusiveness of growth in Africa. It indicated that adequate financing of the health sector is fundamental to improve propoor growth in Africa. The population growth of African countries was found to deteriorate the achievement of inclusiveness of growth. Thus, African countries need to make use of her rising population as a blessing and not as threat, so that pro-poor growth can be achieved in the region. In addition, there is need for more government involvement in financing the health sector by providing adequate health care facilities.
Isolate record for VAFB-ISO-788
Creators: name: Holloway, Corinne
Year: 1900
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Chipped Stone
valueUri: https://core.tdar.org/browse/material-type/2/chipped-stone
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This document is the isolated find record for VAFB-ISO-788. The artifact is a biface base.
Convolutional Framework for Accelerated Magnetic Resonance Imaging
Creators: name: Zhao, Shen
name: Potter, Lee C.
name: Lee, Kiryung
name: Ahmad, Rizwan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides exquisite soft-tissue contrast without using ionizing radiation. The clinical application of MRI may be limited by long data acquisition times; therefore, MR image reconstruction from highly undersampled k-space data has been an active area of research. Many works exploit rank deficiency in a Hankel data matrix to recover unobserved k-space samples; the resulting problem is non-convex, so the choice of numerical algorithm can significantly affect performance, computation, and memory. We present a simple, scalable approach called Convolutional Framework (CF). We demonstrate the feasibility and versatility of CF using measured data from 2D, 3D, and dynamic applications.
description: IEEE ISBI 2020, International Symposium on Biomedical Imaging
Factors Associated with Survival of HIV/HBV Co-infected Patients in Uganda
Creators: name: Atuhaire, Ruth
name: Atuhaire, Leonard
name: Lubaale, Yovani
name: Atuhaire, Ruth
name: Atuhaire, Leonard
name: Lubaale, Yovani
Publisher: name: Unknown
Year: 2016
Subjects: subject: Health Economics and Policy
subject: HIV/HBV co-infected patients
subject: survival analysis
subject: Kaplan and Meier method
subject: proportional hazards model
subject: Uganda

description: The main objective of the study was to identify factors that affect survival of HIV/HBV coinfected patients. The study used data from TASO Uganda. Patients who registered with the organization between 2005 and 2010 were followed to determine their survival. The covariates of study were age, education level, number of sex partners, Disease stage, weight, HBV related condition, being on ARV’s. To estimate the survival function for every subgroup of each variable, the product- limit method developed by Kaplan and Meier was used (Kaplan and Meier, 1958) and a log rank test to compare the survivorship functions across several groups. Lastly,a proportional hazards model was used to examine the joint effect of the covariates on the duration of survival assuming a Gompertz distribution for the time variable. The study revealed the duration of survival for HIV/HBV co-infected patients increased with increasing weight. Patients who had Hepatocellular carcinoma or Cirrhosis at diagnosis were at an increased risk of death as compared to those who had chronic active hepatitis B. Patients on ARVs had an increased death rate as compared to those who were not on ARVs, because the study showed that majority of the Patients seek for treatment when they are infected with Carcinoma, the old stage of Hepatitis B. Given the fact that ARVs have been thought to make life better for HIV/AIDS patients, there is need for further research in this area. Patients who were educated had a reduced death rate as compared to the uneducated ones. Therefore, emphasis should be on designing Information Education Communication (IEC) materials to sensitize the uneducated HIV/HBV co-infected patients on effects of non compliance and unbalanced diets.
Unemployment Menace and the Fallacy of Microcredit Policy in Nigeria
Creators: name: Abdullahi, Ibrahim Bello
name: Sakariyahu, Ola Rilwan
name: Olatunji, Abdulganiy
name: Abdullahi, Ibrahim Bello
name: Sakariyahu, Ola Rilwan
name: Olatunji, Abdulganiy
Publisher: name: Unknown
Year: 2016
Subjects: subject: Financial Economics
subject: Labor and Human Capital
subject: unemployment
subject: microcredit
subject: interest rate
subject: inflation
subject: gross domestic product

description: This study examined the issue of unemployment and the impact of microfinance banks’ credit facilities on its reduction for the period of 22 years between 1992 and 2014. The study employed secondary data obtained from Central Bank of Nigeria and National Bureau of Statistics. The data obtained was subjected to stationarity and cointegration tests with the use of Augmented Dickey-Fuller (ADF) and Phillips-Perron (PP) tests. Furthermore, ordinary least square regression was employed in analyzing the relationship between the dependent variable (unemployment rate) and the independent variables (microfinance banks’ credit facilities, gross domestic product, interest rate and inflation). The outcomes of the study show that three independent variables (microfinance banks’ credit facilities, interest rate and inflation) at 5% alpha level have significant impact on unemployment while gross domestic product was found not to have any significant impact on unemployment. The study concludes that credit facilities provided by microfinance banks do not actually go to deserving individuals or borrowers, thus, having no impact on reducing the menace of unemployment in the country. The study therefore recommends that the Central Bank of Nigeria re-evaluate the performances of the operating microfinance banks in order to ascertain the proportion of their loan portfolio that actually goes to the “unemployed but creative youths”. In addition, the CBN must as a matter of urgency take necessary action in ensuring that loans granted by microfinance banks are serviced at a single digit interest rate as applied in countries like Kenya and Bangladesh. This is because employment generation and overall economic development can only be achieved when entrepreneurial youths can access credit facilities at affordable interest rate.
Free-breathing Cardiovascular MRI Using a Plug-and-Play Method with Learned Denoiser
Creators: name: Liu, Sizhuo
name: Reehorst, Edward
name: Schniter, Philip
name: Ahmad, Rizwan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Cardiac magnetic resonance imaging (CMR) is a noninvasive imaging modality that provides a comprehensive evaluation of the cardiovascular system. The clinical utility of CMR is hampered by long acquisition times, however. In this work, we propose and validate a plug-and-play (PnP) method for CMR reconstruction from undersampled multi-coil data. To fully exploit the rich image structure inherent in CMR, we pair the PnP framework with a deep learning (DL)-based denoiser that is trained using spatiotemporal patches from high-quality, breath-held cardiac cine images. The resulting "PnP-DL" method iterates over data consistency and denoising subroutines. We compare the reconstruction performance of PnP-DL to that of compressed sensing (CS) using eight breath-held and ten real-time (RT) free-breathing cardiac cine datasets. We find that, for breath-held datasets, PnP-DL offers more than one dB advantage over commonly used CS methods. For RT free-breathing datasets, where ground truth is not available, PnP-DL receives higher scores in qualitative evaluation. The results highlight the potential of PnP-DL to accelerate RT CMR.
description: IEEE ISBI 2020, International Symposium on Biomedical Imaging
Isolate record for VAFB-ISO-844
Creators: name: Holloway, Corinne
Year: 1900
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Chipped Stone
valueUri: https://core.tdar.org/browse/material-type/2/chipped-stone
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This document is the isolated find record for VAFB-ISO-844. The artifacts are two primary flakes.
Lowest Order Hadronic Contribution to the Muon g-2
Creators: name: Aubin, Christopher
name: Blum, Tom
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We present the most recent lattice results for the lowest-order hadronic contribution to the muon anomalous magnetic moment using 2+1 flavor improved staggered fermions. A precise fit to the low-q^2 region of the vacuum polarization is necessary to accurately extract the muon g-2. To obtain this fit, we use staggered chiral perturbation theory with the inclusion of the vector particles as resonances, to evaluate the vacuum polarization. We discuss the preliminary fit results and attendant systematic uncertainties, paying particular attention to the relative contributions of the pions and vector mesons.
description: 6 pages, 4 figures, Talk given at Lattice 2005, Dublin
The Socioeconomic Determinants of the Prevalence HIV/AIDS among Women in Cameroon
Creators: name: Bertrand, Nguenda Anya Saturnin
name: Bertrand, Nguenda Anya Saturnin
Publisher: name: Unknown
Year: 2016
Subjects: Health Economics and Policy

description: HIV/AIDS infection is a serious public health problem in Cameroon. It is a main cause of mortality which negatively affects the economic and social development of the country. The last demographic health survey in the country shows that the phenomenon is widespread and affects mostly youths and women. The aim of this study is to analyse the socioeconomic determinants of HIV/AIDS prevalence among women in Cameroon. The methodology is theoretically inspired by the economic rational choice theory of sexual risk behaviour and uses logistic regression for empirical testing. Data is collected from the 2011 Demographic Health Survey of the National Institute of Statistics. The results show that women who have a high probability of being HIV Positive are those who are sexually active, widows or divorced, live in urban areas, uneducated or have primary education, and belong to poor or average income households. These are also women who are physically assaulted, who don’t use condoms, are not aware of HIV/AIDS, have many sexual partners, are unemployed, and have male sexual partners who are older than them.
Ensemble of Deep Convolutional Neural Networks for Automatic Pavement Crack Detection and Measurement
Creators: name: Fan, Zhun
name: Li, Chong
name: Chen, Ying
name: Di Mascio, Paola
name: Chen, Xiaopeng
name: Zhu, Guijie
name: Loprencipe, Giuseppe
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Automated pavement crack detection and measurement are important road issues. Agencies have to guarantee the improvement of road safety. Conventional crack detection and measurement algorithms can be extremely time-consuming and low efficiency. Therefore, recently, innovative algorithms have received increased attention from researchers. In this paper, we propose an ensemble of convolutional neural networks (without a pooling layer) based on probability fusion for automated pavement crack detection and measurement. Specifically, an ensemble of convolutional neural networks was employed to identify the structure of small cracks with raw images. Secondly, outputs of the individual convolutional neural network model for the ensemble were averaged to produce the final crack probability value of each pixel, which can obtain a predicted probability map. Finally, the predicted morphological features of the cracks were measured by using the skeleton extraction algorithm. To validate the proposed method, some experiments were performed on two public crack databases (CFD and AigleRN) and the results of the different state-of-the-art methods were compared. The experimental results show that the proposed method outperforms the other methods. For crack measurement, the crack length and width can be measure based on different crack types (complex, common, thin, and intersecting cracks.). The results show that the proposed algorithm can be effectively applied for crack measurement.
The q-component static model : modeling social networks
Creators: name: Kim, D. -H.
name: Kahng, B.
name: Kim, D.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We generalize the static model by assigning a q-component weight on each vertex. We first choose a component $(μ)$ among the q components at random and a pair of vertices is linked with a color $μ$ according to their weights of the component $(μ)$ as in the static model. A (1-f) fraction of the entire edges is connected following this way. The remaining fraction f is added with (q+1)-th color as in the static model but using the maximum weights among the q components each individual has. This model is motivated by social networks. It exhibits similar topological features to real social networks in that: (i) the degree distribution has a highly skewed form, (ii) the diameter is as small as and (iii) the assortativity coefficient r is as positive and large as those in real social networks with r reaching a maximum around $f \approx 0.2$.
description: 5 pages, 6 figures
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K.
Creators: name: Knight, John Rp
name: Vlahov, Nikola
name: Gay, David M
name: Ridgway, Rachel A
name: Faller, William James
name: Proud, Christopher
name: Mallucci, Giovanna
name: Von Der Haar, Tobias
name: Smales, Christopher Mark
name: Willis, Anne
name: Sansom, Owen J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research Article
Cancer Biology
Cell Biology
translation
protein sythesis
intestinal cancer
in vivo models
RPL24
eEF2K
Mouse

description: Funder: National Health and Medical Research Council; FundRef: http://dx.doi.org/10.13039/501100000925
description: Increased protein synthesis supports the rapid cell proliferation associated with cancer. The Rpl24Bst mutant mouse reduces the expression of the ribosomal protein RPL24 and has been used to suppress translation and limit tumorigenesis in multiple mouse models of cancer. Here, we show that Rpl24Bst also suppresses tumorigenesis and proliferation in a model of colorectal cancer (CRC) with two common patient mutations, Apc and Kras. In contrast to previous reports, Rpl24Bst mutation has no effect on ribosomal subunit abundance but suppresses translation elongation through phosphorylation of eEF2, reducing protein synthesis by 40% in tumour cells. Ablating eEF2 phosphorylation in Rpl24Bst mutant mice by inactivating its kinase, eEF2K, completely restores the rates of elongation and protein synthesis. Furthermore, eEF2K activity is required for the Rpl24Bst mutant to suppress tumorigenesis. This work demonstrates that elevation of eEF2 phosphorylation is an effective means to suppress colorectal tumorigenesis with two driver mutations. This positions translation elongation as a therapeutic target in CRC, as well as in other cancers where the Rpl24Bst mutation has a tumour suppressive effect in mouse models.
Agricultural Trade and Economic Growth in East African Community
Creators: name: Ouma, Duncan
name: Kimani, Tom
name: Manyasa, Emmanuel
name: Ouma, Duncan
name: Kimani, Tom
name: Manyasa, Emmanuel
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agricultural and Food Policy
subject: Agricultural Trade
subject: Economic Growth
subject: East African Community
subject: Regional Integration

description: East African Community states, as many other states in the region, depend largely on agricultural activities to boost their economic growth and create employment. Up to 80 per cent of the populace depends on agriculture directly and indirectly for food, employment and income, while about 40 million people in EAC suffer from hunger. The role of trade in economic growth and vice versa cannot be over emphasized. However, whether there is any link between EAC’s regional trade and the region’s economic growth remain unknown. This study therefore investigated the relationship of the agricultural trade with economic growth in East African Community. Several bi-variate Vector Auto-Regressive (VAR) and Vector Error Correction Models (VECM) were also estimated. Granger causality test and Impulse response analysis on trade and economic growth were performed using panel data from UNCOMTRADE, International Financial Statistics and World Development Indicators for the period 2000 – 2012 on the five EAC members and other 77 trade partners. Empirical findings showed mixed results for the different EAC member states. There existed bi-directional relationship between agricultural exports and economic growth in Kenya, uni-directional relationship in Rwanda, and no relationship at all in Burundi, Tanzania and Uganda.
5526: William James Carnie, killed while driving "Musical Box" near Harbonniers
Creators: name: Project Team, Lest We Forget
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: William James Carnie was an uncle. He was son of William Alexander Carnie and Mary Carnie (née Wilson). He was born on 29/05/1896 at Broomhill, Kintore, Scotland. He worked on the family farm at Broomhill. His brother, John Carnie, and cousins William Alexander Robertson, JamesCharles Robertson and John Cameron Robertson all served in the armed services in the First World War.Around 1915 William James Carnie enlisted in the Machine Gun Corps and had service number 79347. In 1916 he was transferred to the Royal Tank Corps. In September 1917 he trained on the "Whippet" tank as a driver at Bovington camp. His service number was 201966 and he was a private in the 6th Battalion, Royal Tank Corps.On 09/08/1918 William was killed while driving "Musical Box" near Harbonniers. There is no grave but he is commemorated on Panel 11, Vis-en-Artois Memorial, Pas de Calais, France. I have letters and postcards sent home by William. The "Musical Box" action was written up in 1940 as a BBC broadcast by Colonel C.B. Arnold who, as a Lieutenant, had commanded it. I hold an original typed script of the broadcast. William's decorations and medals have not been located.There used to be a William Carnie Memorial Medal presented to the dux of Kintore Public School.
Diversity of gamma-ray and Radio Variabilities of Bright Blazars and Implications for gamma-ray Emission Location
Creators: name: Zhang, Hai-Ming
name: Wang, Zhen-Jie
name: Zhang, Jin
name: Yi, Ting-Feng
name: Chen, Liang
name: Lu, Rui-Jing
name: Liang, En-Wei
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Violent multi-wavelength variabilities are observed in gamma-ray-selected blazars. We present an analysis of long-term light curves for eight bright blazars to explore the co-variation pattern in the gamma-ray and radio bands. We extract their gamma-ray light curves and spectra with data observed by the Fermi/LAT since 2008. We find diverse co-variation patterns between the gamma-ray and radio (at 43 GHz) fluxes in these sources. The gamma-ray and radio fluxes of 3C 454.3 and PKS 1633+382 are correlated without any time-lag, suggesting that they are from the same radiation region. Similar correlation is also observed in 3C 273 and PKS 1222+216, but the radio flux is lag behind the gamma-ray flux approximately ~160 days and ~290 days, respectively. This likely suggests that their gamma-ray emission regions are located at the upstream of their radio cores at 43 GHz. The gamma-ray and radio fluxes of the other four blazars are not correlated, implying that the gamma-ray and radio emission may be from different regions in their jets. The gamma-ray light curves of the eight blazars can be decomposed into some long timescale variability components and fast spike flares. We propose that they may be attributed to the central engine activity and the magnetic reconnection process or turbulence in the local emission region, respectively.
description: 34 pages, 11 figures, 2 tables, accepted for publication in PASJ
Isolate record for VAFB-ISO-857
Creators: name: Holloway, Corinne
Year: 1900
Subjects: subject: Santa Barbara (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3486/santa-barbara-county
subject: Vandenberg Air Force Base (VAFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85469/vandenberg-air-force-base-vafb
subject: Vandenberg Space Force Base (VSFB)
valueUri: https://core.tdar.org/browse/geographic-keyword/85584/vandenberg-space-force-base-vsfb
subject: California (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/1484/california-state-territory
subject: Chipped Stone
valueUri: https://core.tdar.org/browse/material-type/2/chipped-stone
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This document is the isolated find record for VAFB-ISO-857. The artifact is a modified flake.
A Study of \bar{p}p -> Two Neutral Pseudoscalar Mesons at the chi_c0(1^3P_0) Formation Energy
Creators: name: Andreotti, M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Fermilab experiment E835 has studied reactions \bar{p}p -> pi0 pi0, pi0 eta, eta eta, pi0 eta' and eta eta' in the energy region of the chi_c0(1^3P_0) from 3340 MeV to 3470 MeV. Interference between resonant and continuum production is observed in the pi0 pi0 and eta eta channels, and the product of the input and output branching fractions is measured. Limits on resonant production are set for the pi0 eta and pi0 eta' channels. An indication of interference is observed in the eta eta' channel. The technique for extracting resonance parameters in an environment dominated by continuum production is described.
description: 15 pages, 21 figures, submitted Phys. Rev. D
5529: John Carnie, who served in Cyprus, Egypt and the Middle East
Creators: name: Project Team, Lest We Forget
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: John Carnie was an uncle. He was son of William Alexander Carnie and Mary Carnie (née Wilson). He was born in 1897 at Broomhill, Kintore, Scotland. In 1914 he was an apprentice engineer with William Mackinnon, Spring Garden, Aberdeen. His brother, William James Carnie, and cousins William Alexander Robertson, James Charles Robertson and John Cameron Robertson all served in the armed services in the First World War.John Carnie enlisted in the Royal Flying Corps and had service number 163342. He served in Cyprus, Egypt and the Middle East. He was with 144 Squadron after it was formed at Port Said on 20/03/1918. His rank was up to Sergeant and trade Armourer. After the war he returned to William Mackinnon and rose to be works manager, before leaving to develop and manufacture his own inventions.
Dynamics of Mask Use as a Prevention Strategy against SARS-CoV-2 in Panama.
Creators: name: Fernández-Marín, Hermógenes
name: Bruner-Montero, Gaspar
name: Portugal-Loayza, Ana
name: Miranda, Virginia
name: Villarreal Dominguez, Alcibiades Elias
name: Ortega-Barría, Eduardo
name: Núñez-Samudio, Virginia
name: Landires, Iván
name: Mejía, Luis C
name: López-Vergès, Sandra
name: Wcislo, William T
name: Kosagisharaf, Jagannatha Rao
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: surgical mask
cloth mask
population response
behavioral modifications
public health

description: Early in the SARS-CoV-2 pandemic, many national public health authorities implemented non-pharmaceutical interventions to mitigate disease outbreaks. Panamá established mandatory mask use two months after its first documented case. Initial compliance was high, but diverse masks were used in public areas. We studied behavioral dynamics of mask use through the first two COVID-19 waves in Panama, to improve the implementation of effective, low-cost public health containment measures when populations are exposed to novel air-borne pathogens. Mask use behavior was recorded from pedestrians in four Panamanian populations (August to December 2020). We recorded facial coverings and if used, the type of mask, and gender and estimated age of the wearer. Our results showed that people were highly compliant (>95%) with mask mandates and demonstrated important population-level behaviors: (1) decreasing use of cloth masks over time, and increasing use of surgical masks; (2) mask use was 3-fold lower in suburban neighborhoods than other public areas and (3) young people were least likely to wear masks. Results help focus on highly effective, low-cost, public health interventions for managing and controlling a pandemic. Considerations of behavioral preferences for different masks, relative to pricing and availability, are essential for optimizing public health policies. Policies to increase the availability of effective masks, and behavioral nudges to increase acceptance, and to facilitate mask usage, during the ongoing SARS-CoV-2 pandemic, and for future pandemics of respiratory pathogens, are key tools, especially for nations lagging in access to expensive vaccines and pharmacological approaches.
Two characteristic temperatures for a Bose-Einstein condensate of a finite number of particles
Creators: name: Idziaszek, Z.
name: Rzazewski, K.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider two characteristic temperatures for a Bose-Einstein condensate, that are related to certain properties of the condensate statistics. We calculate them for an ideal gas confined in power-law traps and show that they approach the critical temperature in the limit of large number of particles. The considered characteristic temperatures can be useful in the studies of Bose-Einstein condensates of a finite number of atoms, indicating the point of a phase transition.
description: 4 pages, 2 figures; v2: references added
Transaction cost determinants of credit governance structures of commercial banks in Tanzania
Creators: name: Nguvava, Heriel
name: Ngaruko, Deus
name: Nguvava, Heriel
name: Ngaruko, Deus
Publisher: name: Unknown
Year: 2016
Subjects: subject: Financial Economics
subject: Industrial Organization
subject: Transaction costs
subject: credit governance structures
subject: commercial banks
subject: Tanzan

description: This paper explores transaction cost determinants of credit governance structures (CGS) of commercial banks in Tanzania. Descriptive statistics, linear regression model, binary and multinomial logistic regression models were employed for analysis. Findings revealed four modes of credit governance structures that are used by commercial banks to penetrate rural based credit market without fear of high transaction costs. These modes of CGSs might be used to absorb transaction costs in different magnitudes, allow commercial banks credit operations scale up to rural areas and maximize profitability. The most important TC determinants include high illiteracy rate (lack of entrepreneurial and financial management skills), poor infrastructures, unclear political will and commitment towards rural development, culture barrier (poor tradition and customs) and lack of national identification system. It was also revealed that, under commercial banks credit operations in Tanzania, credit contract monitoring and enforcement transaction costs were the highest categories of TCs, which is contrary to what suggested by previous authors.
Diverging length scale and upper critical dimension in the Mode-Coupling Theory of the glass transition
Creators: name: Biroli, Giulio
name: Bouchaud, Jean-Philippe
Publisher: name: arXiv
Year: 2004
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We show that the glass transition predicted by the Mode-Coupling Theory (MCT) is a critical phenomenon with a diverging length and time scale associated to the cooperativity of the dynamics. We obtain the scaling exponents nu and z that relate space and time scales to the distance from criticality, as well as the scaling form of the critical four-point correlation function. However, both these predictions and other well known MCT results are mean-field in nature and are thus expected to change below the upper critical dimension dc=6, as suggested by different forms of the Ginzburg criterion.
description: 7 pages, 2 figures. Final version accepted on Europhysics Letters
5408: Alexander Watson Forbes, Gordon Highlander
Creators: name: Project Team, Lest We Forget
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Alexander Watson Forbes was my grandfather (father's father). He was born on 11/02/1893 and was a fish buyer in Civvie Street. He served in the First World War as a sergeant in the 1st Battalion, Gordon Highlanders with service number S/6948. He served in France for the whole duration 1914-1918 but was wounded. He was awarded the DCM in 1918. We have a large frame containing hankies and postcards from the First World War. I can remember the frame always being in Grandmother's house. The couple stayed at 162 Victoria Road, Torry, Aberdeen, Scotland. Alexander died on 07/05/1932 of tonsillitis, which might have been as a result of wounds. He was buried in Allenvale Cemetery, Aberdeen. The family spoke a lot about grandfather. His widow was left with three young children. I have a newspaper cutting about grandfather.
title: HIV-1 Infection in Kenyan Infants: Natural History and T cell Responses
Creators: name: Slyker, Jennifer Ann
Publisher: name: The Open University
Year: 2007

description: This thesis describes human immunodeficiency virus type 1 (HIV-1) infection in Kenyan infants. Paediatric HIV-1 infection causes rapid disease progression in the absence of antiretroviral (ARV) therapy. African cohorts have reported the highest rates of mortality, from 20-50% at 2 years of life. Understanding the pathogenesis in HIV-1 infected children is important to the design of prevention, treatment, and vaccination strategies. A cohort of 476 Kenyan children born to HIV-1 infected women was studied longitudinally from the time of birth to 24 months. Despite the provision of ARVs to prevent mother-to-child transmission, 19.4% of infants became infected with HIV-1. Infant HIV-1 infection resulted in persistently high levels of viraemia and rapid CD4 depletion. Cumulative mortality at 2 years was 54%. Peak and set-point HIV-1 viral load, and CD4% at 6 months were predictors of 2-year mortality. Co-infection with cytomegalovirus (CMV) before the age of 1 month was also associated with increased risk of death. Infants with HIV-1 infection had poorly contained CMV viraemia in comparison with HIV-1 exposed uninfected controls. Multicolour flow cytometry was used to describe the phenotype of T cells during primary viral infection. Both CMV and HIV-1 infection resulted in dynamic redistribution of T cell populations. High frequencies of activated, apoptotic vulnerable, differentiating CD8 T cells were observed concurrent to acute infection with either HIV-1 or CMV. Co-infection with both viruses resulted in even more profound changes in cellular phenotype. CD4 T cell phenotype was also affected by acute viral infection, but at a much lower magnitude than observed in the CD8 subset. HIV-1 specific CD8 T cells were studied in a subset of infants using IFN-γ ELISpot assays and tetramer staining. Very high frequencies of HIV-1 specific CD8 T cells were identified with tetramer staining, and these cells resembled adult T cell responses in magnitude and phenotype. ELISpot assays revealed weak responses in infants less than 6 months old that increased with age. These data suggest that HIV-1 specific CD8 T cell responses can be generated during acute infection in infants, but IFN-γ production is lower compared to adult cells. Reduced functional capacity may explain the inability of infant T cell responses to contain HIV-1 viral load.