cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Chin Yim, Lee Hoo, Tsang Gay Hop, Chow Kong, Chu Bing Luong, Chu Won Chee, Jon Sing, Lew Kong Watt, Fong Shee Kong, Fong Wuck.
Supplementary Materials of Beneficial Microbes: Disordered gut microbiota in postmenopausal stage amplifies intestinal tight junction damage to accelerate atherosclerosis
Creators: name: Meng, Qinghai
name: Zhang, Shurui
name: Zhang, Chenyan
name: Liu, Bowen
name: Zhu, Weijie
name: Wu, Lixing
name: Zhang, Qichun
name: Li, Yu
name: Wang, Xiaoliang
name: Bian, Huimin
Publisher: name: Brill Online
Year: 2024
Subjects: classificationCode: 320209
subject: Gastroenterology and hepatology
classificationCode: 320223
subject: Rheumatology and arthritis

description: The causes and characteristics of gut microbiota abnormalities and whether microbiota manipulation can prevent atherosclerosis in the postmenopausal stage remain to be determined. Aortic oestrogen receptor expression, histological changes and gut microbiota in women before and after menopause were detected. Serum oestrogen levels, systemic inflammation, intestinal oestrogen receptor expression and histological changes, atherosclerosis, and gut microbiota in low density lipoprotein deletion (LDLR-/-) female mice before and after ovariectomy were tested. This study examined aortic oestrogen receptor expression, histological changes, and gut microbiota in women before and after menopause, and tested serum oestrogen levels, systemic inflammation, intestinal oestrogen receptor expression, histological changes, atherosclerosis, and gut microbiota in low-density lipoprotein receptor knockout (LDLR-/-) female mice before and after ovariectomy. We demonstrated that the downregulation of oestrogen and oestrogen receptors after menopause promotes gut microbiota disturbance in both women and female mice. We found that gut microbiota disturbance amplifies the intestinal barrier damage and aggravates systemic inflammation, thereby promoting atherosclerosis in female mice. Faecal microbiota transplantation and antibiotics inhibit the proinflammatory properties of gut microbiota and prevent atherosclerosis by reducing intestinal barrier damage in postmenopausal mice. Together, our study highlights the causes of gut microbiota disturbances and the role of microbiota manipulation in preventing atherosclerosis in postmenopausal stage.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Sung Fook Hin, Pon Wook, Kwan Yuey, Mah Hing, [Mah Loc], Wong Sai Ying, Long Yong Yee, Chin Ying, [Hine Dun Wah], [Hune Jan On].
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: [Mrosam Mah Shee], [Kwan Ting Leong], Mr. Lee Ying, Mr. G. Kant, Mrs. G. Kant, Law Shee, [Master Earnest Leong], Lew Fat, Lew Yuey Chong, [Lew Chee Shoot], Lew Yuey Quan, Lew Mee Ting, [Lew Mee Yead], H. Mah, Lee
First-Order Trotter Error from a Second-Order Perspective
Creators: name: Layden, David
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Simulating quantum dynamics beyond the reach of classical computers is one of the main envisioned applications of quantum computers. The most promising quantum algorithms to this end in the near-term are the simplest, which use the Trotter formula and its higher-order variants to approximate the dynamics of interest. The approximation error of these algorithms is often poorly understood, even in the most basic cases, which are particularly relevant for experiments. Recent studies have reported anomalously low approximation error with unexpected scaling in such cases, which they attribute to quantum interference between the errors from different steps of the algorithm. Here we provide a simpler picture of these effects by relating the Trotter formula to its second-order variant. Our method generalizes state-of-the-art error bounds without the technical caveats of prior studies, and elucidates how each part of the total error arises from the underlying quantum circuit. We compare our bound to the true error numerically, and find a close match over many orders of magnitude in the simulation parameters. Our findings reduce the required circuit depth for the most basic quantum simulation algorithms, and illustrate a useful method for bounding simulation error more broadly.
description: 5 pages, 2 figures
The Scribble Cell Polarity Module in the Regulation of Cell Signaling in Tissue Development and Tumorigenesis
Creators: name: Stephens, Rebecca
name: Lim, Krystle
name: Portela-Esteban, Marta
name: Kvansakul, Marc
name: Humbert, Patrick
name: Richardson, Helena
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3107
subject: Microbiology

description: The Scribble cell polarity module, comprising Scribbled (Scrib), Discs-large (Dlg) and Lethal-2-giant larvae (Lgl), has a tumor suppressive role in mammalian epithelial cancers. The Scribble module proteins play key functions in the establishment and maintenance of different modes of cell polarity, as well as in the control of tissue growth, differentiation and directed cell migration, and therefore are major regulators of tissue development and homeostasis. Whilst molecular details are known regarding the roles of Scribble module proteins in cell polarity regulation, their precise mode of action in the regulation of other key cellular processes remains enigmatic. An accumulating body of evidence indicates that Scribble module proteins play scaffolding roles in the control of various signaling pathways, which are linked to the control of tissue growth, differentiation and cell migration. Multiple Scrib, Dlg and Lgl interacting proteins have been discovered, which are involved in diverse processes, however many function in the regulation of cellular signaling. Herein, we review the components of the Scrib, Dlg and Lgl protein interactomes, and focus on the mechanism by which they regulate cellular signaling pathways in metazoans, and how their disruption leads to cancer.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: [Young Houk Yee], Young Gim Tong, Wong Wing Chung, [Wong Hip Shue], [Young Ghim Jan], Yip Kee Hing, Jsang Gar Chong, Leong Jor, Wong Ko, Ng Leong Pook.
title: Risks, Dangers, and Threat Models: Evaluating Security Analysis for Conflict Practitioners
Creators: name: Loadenthal, Michael
name: Nielsen, Peyton
name: McCarthy, Devin
Publisher: name: Better Evidence Project
Year: 2021
Subjects: subject: Security
subject: Aid Workers
subject: Technology

description: The risks to conflict practitioners, peacemakers, humanitarian aid workers, and others serving ‘in the field’ are diverse, deeply contextual, and ever-changing. While ample literature exists focused around documenting and evaluating the history of these dangers, far fewer resources have been authored to promote a comprehensive, proactive, and agile framework for predicting, observing, and understanding risks and threats to one's safety and security. While it is true that many organizations provide their employees with carefully-written guides containing security ‘dos and don’ts,’ what are practitioners meant to do when the conditions on the ground change? Instead of providing fixed solutions to emergent problems, this paper argues for a flexible framework to understand security and risk, and as a result, facilitates the development of a sustained, adaptable security posture and risk balance.
Margen de Disponibilidad de los Derechos Laborales Irrenunciables afectados por la Licencia Covid-19
Creators: name: Romero Linares, Anna Paula Lorena
Publisher: name: Universidad Católica de Santa María
Year: 2024
Subjects: Irrenunciabilidad
Disponibilidad de derechos
Licencia Covid

description: La presente investigación busca analizar la existencia de una dimensión disponible de los derechos irrenunciables laborales que se vieron afectados durante la pandemia del Covid-19, siendo que este carácter de disponibilidad no afecte en absoluto el principio de irrenunciabilidad de derechos laborales ni el contenido constitucionalmente protegido de los derechos. Esta situación se produjo a raíz de una secuencia de hechos atípicos generados por el Estado de Emergencia Sanitario por la pandemia del Covid-19 por lo que el derecho, y en particular, el derecho laboral tuvo que adaptarse con el fin de proteger al trabajador y al empleador. Durante el desarrollo de esta tesis, se analizará lo referente al principio de irrenunciabilidad y sus diferencias con los actos de disponibilidad; este análisis incluirá pensamientos doctrinarios y manifestaciones jurisprudenciales de ambas figuras. Posteriormente se analizará el impacto de la licencia Covid-19, originada en el 2020, en las relaciones laborales entre empresas y trabajadores incluyendo entrevistas a expertos en la materia y pronunciamientos judiciales al respecto. Finalmente se demostrará que los actos de disponibilidad de derechos irrenunciables, siempre y cuando cumplan con ciertos requisitos en su ejercicio, no afectan el principio de irrenunciabilidad y, por el contrario, son una manifestación del derecho de los trabajadores.
Tree boosting for learning EFT parameters
Creators: name: Chatterjee, Suman
name: Frohner, Nikolaus
name: Lechner, Lukas
name: Schöfbeck, Robert
name: Schwarz, Dennis
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a new tree boosting algorithm designed for the measurement of parameters in the context of effective field theory (EFT). To construct the algorithm, we interpret the optimized loss function of a traditional decision tree as the maximal Fisher information in Poisson counting experiments. We promote the interpretation to general EFT predictions and develop a suitable boosting method. The resulting ``Boosted Information Tree'' algorithm approximates the score, the derivative of the log-likelihood function with respect to the parameter. It thus provides a sufficient statistic in the vicinity of a reference point in parameter space where the estimator is trained. The training exploits per-event information of likelihood ratios for different theory parameter values available in the simulated EFT data sets.
description: 23 pages, 3 figures. Updated with referee comments
Research priorities in health communication and participation: international survey of consumers and other stakeholders
Creators: name: Synnot, Anneliese
name: Bragge, Peter
name: Lowe, Dianne
name: Nunn, Jack
name: O’Sullivan, Molly
name: Horvat, Lidia
name: Tong, Allison
name: Kay, Debra
name: Ghersi, Davina
name: McDonald, Steve
name: Poole, Naomi
name: Bourke, Noni
name: Lannin, Natasha
name: Vadasz, Danny
name: Oliver, Sandy
name: Carey, Karen
name: Hill, Sophie
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: Objective: To identify research priorities of consumers and other stakeholders to inform Cochrane Reviews in 'health communication and participation' (including such concepts as patient experience, shared decision-making and health literacy). Setting International. Participants: We included anyone with an interest in health communication and participation. Up to 151 participants (18-80 years; 117 female) across 12 countries took part, including 48 consumers (patients, carers, consumer representatives) and 75 professionals (health professionals, policymakers, researchers) (plus 25 people who identified as both). Design Survey. Methods: We invited people to submit their research ideas via an online survey open for 4 weeks. Using inductive thematic analysis, we generated priority research topics, then classified these into broader themes. Results: Participants submitted 200 research ideas, which we grouped into 21 priority topics. Key research priorities included: Insufficient consumer involvement in research (19 responses), 'official' health information is contradictory and hard to understand (18 responses), communication/coordination breakdowns in health services (15 responses), health information provision a low priority for health professionals (15 responses), insufficient eliciting of patient preferences (14 responses), health services poorly understand/implement patient-centred care (14 responses), lack of holistic care impacting healthcare quality and safety (13 responses) and inadequate consumer involvement in service design (11 responses). These priorities encompassed acute and community health settings, with implications for policy and research. Priority populations of interest included people from diverse cultural and linguistic backgrounds, carers, and people with low educational attainment, or mental illness. Most frequently suggested interventions focused on training and cultural change activities for health services and health professionals. Conclusions: Consumers and other stakeholders want research addressing structural and cultural challenges in health services (eg, lack of holistic, patient-centred, culturally safe care) and building health professionals' communication skills. Solutions should be devised in partnership with consumers, and focus on the needs of vulnerable groups.
title: Sully: The Life & Times of Sully
Creators: name: Ferrell, Linden
Publisher: name: George Mason University
Year: 2016
Subjects: subject: Chantilly (Va.)
subject: Lee, Richard Bland, 1761-1827
subject: Slavery
subject: Plantations

description: To view this project, download and install the Web Archive Player from https://github.com/ikreymer/webarchiveplayer or upload the .warc.gz file to https://webrecorder.io/.
description: Sully Plantation is a little historic site that is located very close to the Washington D.C. area. Situated right in Chantilly and next to the Dulles Airport, this site is a perfect place to visit. There are nice, light and easy hiking trails that offer a great view of the plantation. Even though it is a lesser known site, it is important nonetheless! This site is intriguing because of its rich history about not only the families that lived there, but the slaves that worked on the property. The property has undergone many changes as its purpose differed for every owner. However, upon entering this site, the focus will be on the Richard Bland Lee Period (1787-1811) and comparing the lives of both slaves and owners.
Asociación entre los grados de severidad de fluorosis y caries dental en estudiantes de 8-16 años de la I.E Alma Mater de Congata, I.E. Reino de Bélgica y I.E.P Santa María del Valle ubicados en Uchumayo, Arequipa 2023
Creators: name: Maza Calcina, Andrea Looana
Publisher: name: Universidad Católica de Santa María
Year: 2024
Subjects: Fluorosis dental
Caries Dental
Asociación

description: OBJETIVO: la fluorosis y caries dental son temas que concierne a la salud pública en el Perú. Por esta razón se realizó esta investigación con el objetivo de evidenciar si existe alguna asociación entre la severidad de la fluorosis y la caries dental en estudiantes de la I.E Alma Mater de Congata, I.E. Reino de Bélgica y I.E.P Santa María del Valle ubicados en Uchumayo en Arequipa año 2023. MATERIALES Y MÉTODOS: el estudio se realizó a través de un diseño no experimental, observacional, transversal, de asociación, comparación y clínico, se seleccionó una población de 580 estudiantes de ambos géneros con edades comprendidas entre los 8 y 16 años, se entregó consentimientos informados a los padres y asentimientos informados a los estudiantes para su participación voluntaria. Así mismo se obtuvo la aprobación del Comité de Ética No 010-2023 de la UCSM. Durante el examen clínico, la recolección de datos se registró en una ficha validada por la OMS y modificada por Dra. Zaida Moya de Calderón, odontopediatra y docente de la UCSM, que permite el diagnóstico de la severidad de la fluorosis dental a través del índice de Dean y de la experiencia de caries dental a través del índice CPO-D/ceo-d de forma integral. RESULTADOS: se observó que el 98,10% de los estudiantes presentan fluorosis y el grado con mayor porcentaje es el moderado, el colegio con mayor prevalencia fue Alma Mater de Congata. En cuanto a la caries dental se encontró que el ceo-d poblacional fue muy leve con mayor prevalencia en Alma Mater de Congata y el CPO-D poblacional fue leve con mayor prevalencia en el colegio Reino de Bélgica. CONCLUSIÓN: existe asociación entre la severidad de fluorosis y caries dental en dientes deciduos (p=0,01). Sin embargo, no se encontró dicha asociación en dientes permanentes (p=0,1), al aumentar la severidad de fluorosis, el índice CPO-D disminuye. A pesar de los hallazgos, enfatizamos la importancia de una continua investigación sobre la asociación entre ambas condiciones desde un enfoque de salud pública
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Lee Jong Chow, Lee Hong, Hew Yin Joy, Wong Quon, Song Hing, Yip Chung, Chun Hoy, Kong Ling, Young Yow, Wong Moo Joon.
title: ÐÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½Ð°Ñ Ð³ÑÐ°ÑÐ¸ÐºÐ° Ð² ÐºÐ¸Ð½Ð¾ÐºÐ°Ð´ÑÐµ. Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð²Ð¸Ð´ÐµÐ¾Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð°
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: Ð¯Ð½ÑÑÑ, ÐÐ¸ÐºÑÐ¾Ñ
name: ÐÐ¾ÑÐµÐ²Ð¸Ñ, ÐÐºÐ°ÑÐµÑÐ¸Ð½Ð°
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2023
Subjects: ÐÐ°ÑÐ¸Ð½Ð½Ð°Ñ Ð³ÑÐ°ÑÐ¸ÐºÐ°
ÐÐ¸Ð½Ð¾ÑÐµÑ Ð½Ð¸ÐºÐ°
ÑÐµÐºÐ»Ð°Ð¼Ð½ÑÐ¹ Ð´Ð¸Ð·Ð°Ð¹Ð½
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: Ð£ÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ ÑÐ°ÑÐºÑÑÐ²Ð°ÐµÑ ÑÐ¾Ð´ÐµÑÐ¶Ð°Ð½Ð¸Ðµ ÑÑÐµÐ±Ð½Ð¾Ð¹ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ñ Â«ÐÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½Ð°Ñ Ð³ÑÐ°ÑÐ¸ÐºÐ°. ÐÐ°Ð·Ð¾Ð²ÑÐ¹ ÐºÑÑÑ (ÐÐ¸Ð·Ð°Ð¹Ð½. ÐÑÐ¾ÑÐ¸Ð»Ñ: Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð´Ð¸Ð·Ð°Ð¹Ð½, Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð´Ð¸Ð·Ð°Ð¹Ð½)Â». Ð Ð´Ð°Ð½Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð²ÐºÐ»ÑÑÐµÐ½Ñ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ Ð¿Ð¾ Ð²ÑÐµÐ¼ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐ¼ ÑÐµÐ¼Ð°Ð¼ ÐºÑÑÑÐ° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÐºÐ°Ð´ÑÐ° Ð² Ð¿ÑÐ¾ÑÐµÑÑÐµ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð²Ð¸Ð´ÐµÐ¾ÑÐ¸Ð»ÑÐ¼Ð°. ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ ÑÑÑÐ´ÐµÐ½ÑÐ°Ð¼Ð¸ Ð·Ð½Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑ Ð¸Ð¼ ÑÐ¾Ð·Ð´Ð°Ð²Ð°ÑÑ ÑÐµÐºÐ»Ð°Ð¼Ð½ÑÐµ, ÑÐµÐºÐ»Ð°Ð¼Ð½Ð¾-Ð¿ÑÐµÐ·ÐµÐ½ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð¸ ÑÑÐ´Ð¾Ð¶ÐµÑÑÐ²ÐµÐ½Ð½ÑÐµ Ð²Ð¸Ð´ÐµÐ¾ÑÐ¾Ð»Ð¸ÐºÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ñ Ð² Ð¿ÑÐ¾ÑÐµÑÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸. ÐÐ¾ÑÐ¾Ð±Ð¸Ðµ Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð¾Ð±ÑÑÐ°ÑÑÐ¸ÑÑÑ Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ (ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÐ¸) Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Â«ÐÐ¸Ð·Ð°Ð¹Ð½. ÐÑÐ¾ÑÐ¸Ð»Ñ: Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð´Ð¸Ð·Ð°Ð¹Ð½, Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð´Ð¸Ð·Ð°Ð¹Ð½Â».
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Woo Chow, Goon Fay, Lee Yin Chong, Ko Yat, Mah Yong Yee, Wong Jong Bing, Hong Lin Gon, Hong Doy Yow, Kwock Sik Foon, Chan Luon Fon.
Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis
Creators: name: Kim, Soo-Hyun
name: Redvers, Richard
name: Chi, Lap Hing
name: Ling, Xiawei
name: Lucke, Andrew J
name: Reid, Robert C
name: Fairlie, David P
name: Martin, Ana Carolina Baptista Moreno
name: Anderson, Robin
name: Denoyer, Delphine
name: Pouliot, Normand
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3204
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: 3211
subject: Oncology and carcinogenesis

description: Breast cancer brain metastases remain largely incurable. Although several mouse models have been developed to investigate the genes and mechanisms regulating breast cancer brain metastasis, these models often lack clinical relevance since they require the use of immunocompromised mice and/or are poorly metastatic to brain from the mammary gland. We describe the development and characterisation of an aggressive brain metastatic variant of the 4T1 syngeneic model (4T1Br4) that spontaneously metastasises to multiple organs, but is selectively more metastatic to the brain from the mammary gland than parental 4T1 tumours. As seen by immunohistochemistry, 4T1Br4 tumours and brain metastases display a triple-negative phenotype, consistent with the high propensity of this breast cancer subtype to spread to brain. In vitro assays indicate that 4T1Br4 cells have an enhanced ability to adhere to or migrate across a brain-derived endothelial monolayer and greater invasive response to brain-derived soluble factors compared to 4T1 cells. These properties are likely to contribute to the brain selectivity of 4T1Br4 tumours. Expression profiling and gene set enrichment analyses demonstrate the clinical relevance of the 4T1Br4 model at the transcriptomic level. Pathway analyses implicate tumour-intrinsic immune regulation and vascular interactions in successful brain colonisation, revealing potential therapeutic targets. Evaluation of two histone deacetylase inhibitors, SB939 and 1179.4b, shows partial efficacy against 4T1Br4 metastasis to brain and other sites in vivo, and potent radio-sensitising properties in vitro. The 4T1Br4 model provides a clinically relevant tool for mechanistic studies and to evaluate novel therapies against brain metastasis.
title: Draft: Advisory Committee Resolution on James M. Shea, Jr.
Creators: name: Anonymous
Publisher: name: George Mason University
Year: 2007
Subjects: subject: Shea, James M., Jr.
subject: George Mason College

description: Resolution: 2 pgs, typescript, unsigned, 11" x 8.5" (29.7 cm x 21.6 cm)
description: Undated draft of a resolution by the Advisory Committee of George Mason College to terminate Assistant Professor of Philosphy James M. Shea, Jr.'s employment for numerous infractions primarily related to anti-war activities. C. Harrison Mann, Jr. Collection 19.16
Asociación del tabaquismo y del consumo de anticonceptivos orales con la melanosis gingival en pacientes de la Consulta Privada. Arequipa, 2023
Creators: name: Eugenio Toledo, Edwar
Publisher: name: Universidad Católica de Santa María
Year: 2024
Subjects: Tabaquismo
Anticonceptivos
Melanosis gingival

description: El presente estudio tiene como propósito evaluar la asociación del tabaquismo y del consumo de anticonceptivos orales en la melanosis gingival en pacientes de la consulta privada. Se trata de una investigación comunicacional, observacional, prospectivo, transversal, comparativo y de nivel relacional. Las variables independientes fueron analizadas por la técnica de cuestionario. La variable dependiente, por observación clínica intraoral, requiriendo una ficha de registro para la operativización de ambas técnicas en 62 pacientes por grupo. La información obtenida producto de la recolección fue tratada estadísticamente a través de frecuencia numéricas y relativas. La comparación fue analizada por medio del contraste X2, dado la índole cualitativa de la variable de interés. Los hallazgos mostraron que el tabaquismo tuvo una mayor injerencia en una melanosis gingival severa, con el 45.16%; y, el consumo de anticonceptivos orales influyó de forma predominante en una melanosis leve con el 80.65%. Según el contraste X2 de homogeneidad, existe diferencia estadística significativa en la influencia de tabaquismo y de los anticonceptivos orales en el grado de melanosis de la encía, más no en la distribución de dicha condición, por lo que se acepta la hipótesis investigativa en el primer caso (p < 0.05); y, la hipótesis nula en el segundo (p > 0.05).
Quantum Floquet engineering with an exactly solvable tight-binding chain in a cavity
Creators: name: Eckhardt, Christian J.
name: Passetti, Giacomo
name: Othman, Moustafa
name: Karrasch, Christoph
name: Cavaliere, Fabio
name: Sentef, Michael A.
name: Kennes, Dante M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Recent experimental advances enable the manipulation of quantum matter by exploiting the quantum nature of light. However, paradigmatic exactly solvable models, such as the Dicke, Rabi or Jaynes-Cummings models for quantum-optical systems, are scarce in the corresponding solid-state, quantum materials context. Focusing on the long-wavelength limit for the light, here, we provide such an exactly solvable model given by a tight-binding chain coupled to a single cavity mode via a quantized version of the Peierls substitution. We show that perturbative expansions in the light-matter coupling have to be taken with care and can easily lead to a false superradiant phase. Furthermore, we provide an analytical expression for the groundstate in the thermodynamic limit, in which the cavity photons are squeezed by the light-matter coupling. In addition, we derive analytical expressions for the electronic single-particle spectral function and optical conductivity. We unveil quantum Floquet engineering signatures in these dynamical response functions, such as analogs to dynamical localization and replica side bands, complementing paradigmatic classical Floquet engineering results. Strikingly, the Drude weight in the optical conductivity of the electrons is partially suppressed by the presence of a single cavity mode through an induced electron-electron interaction.
OIKODOMOS: Proposal for enhanced environment
Creators: name: Riddy, Paul
name: Fill, Karen
name: Botturi, Luca
name: Schmell, Andreas
name: Madrazo, Leandro
name: Sicilia, Álvaro
Publisher: name: Zenodo
Year: 2008
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: Architecture
subject: Urban studies
subject: Housing
subject: Environmental sustainability
subject: Innovation
subject: Education
subject: Learning
subject: Educational Technology/education

description: Building on the results presented in the report PRE EP 1: “Assessment of the Existing Web-Based Platform”, this report describes the indications, guidelines and requirements for the design and implementation of new platforms/environments which will be used within OIKODOMOS. The document is divided in general specifications (section 1), definition of content types and classification structures (section 2), database structure (section 3), user interface and navigation (section 4, which also includes a wireframe functional mockup of the application interface), and the definition of application modules and work distribution.
Middle-aged same-sex attracted women and the social practice of drinking
Creators: name: MacLean, Sarah
name: Michael, Savic
name: Pennay, Amy
name: Dwyer, Robyn
name: Stanesby, Oliver
name: Wilkinson, Claire
Publisher: name: La Trobe
Year: 2021
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4206
subject: Public health
classificationCode: 4401
subject: Anthropology
subject: FOS: Sociology
classificationCode: 4410
subject: Sociology

description: As a group, middle-aged same-sex attracted women (SSAW) appear to consume more alcohol than exclusively heterosexual women in the same age range; however, few studies document their collective drinking practices or identify opportunities to reduce associated harms. Online surveys which included open-ended questions were completed by a self-selected sample of SSAW (N = 134) aged 36–51, recruited in Victoria, Australia. We identify 12 sub-elements of SSAW’s collective drinking practice using a schema grounded in social practice theory (SPT). Responses are compared for SSAW who consumed alcohol with others at moderate and at heavier levels, based on screening. Heavier drinking respondents were more likely to observe that: alcohol use is normalised for SSAW; they are not pressured to drink; drinking produces pleasurable effects; drinking facilitates management of uncomfortable moods and that venues welcoming SSAW are saturated with alcohol. In line with SPT, links between sub-elements described by heavier drinkers are explored to identify potential interventions. For example, we recommend an expansion of social opportunities without alcohol that engender affirming affective states for SSAW. Further, many SSAW’s commitment to the importance of moderation and rejecting coercion to drink could be used to combat the conviction that drinking is an inevitable response to discrimination experienced by sexual minorities. It was apparent that although they drank with other SSAW, our survey respondents did not share a consistent or altogether unique drinking culture. We suggest that an SPT approach entailing data coding to multiple sub-elements supports the identification of diverse configurations of drinking practice within heterogeneous subpopulations.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Lee Pool Bill, Jung Yuen, Wong Moon Sing, [Wong Yong Gumn], Mah Soon, Chow Hai King, Jone Dew, Jone Yuey, Louie Bit Ming, Louie Hong Yick.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: [Jung Lan Sing], Jung Sik Kee, Jung Shew, Jung How Pon, Yee Loon Goon, Leong Kim Hong, Mah Lung, Jung Gee Yuey, [Woo Bing Chor], [Fon Wa Sau].
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Woo Yong Fat, Woo Quon, Chee Bon Shong, [Wang Jack], Leong Mon, [Lew Gup Kin], Jang Gee Chong, Yip Ark Fee, Lee Oy Yow, Chin Ying Wah.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Lim Wong, Yun Yew Hing, Soo Gow, Chan Dan Kew, Chan Wing Dan, Chan Chew, Chan Wah Shing, Goon Wah, Leong Lum, Lew Hee Toon.
title: Paper: "Parker-Hannifin IM Workshops-2007," January 2009
Creators: name: Warfield, John
Publisher: name: George Mason University
Year: 2009
Subjects: subject: Hydraulic Systems Division (HSD)
subject: Warfield, John N.
subject: Moreno, Carmen
subject: Broome, Ben
subject: Ernzen, Phil
subject: Interactive Management (IM)
subject: Parker-Hannifin

description: Manuscript: typescript with images (color). Original document is PDF (2.86 Mb), 7 pgs. 8.5" x 11" (21.6 cm x 29.7 cm)
description: This is a collection of photographs of participants and leaders of an Interactive Management session held with members of the Hydraulic Systems Division at Parker-Hannifin in 2007. Accompanying each photograph is a description written by Warfield. John N. Warield Collection 99.7
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Chan Fon, Jang Yong Ho, Wong Sing Lin, Lee Mow Luon, Yip Lee Sang, Wong Gim Soon, Jang Yuey Hing, Jang Sair King, Wong Ho, Wong Chew.
title: As Though Outside
Creators: name: Creightney, Anya
Publisher: name: George Mason University
Year: 2015
Subjects: subject: Legend
subject: Copenhagen
subject: Take Over
subject: Min Mor
subject: Kamal
subject: Tennis

description: This work was embargoed by the author and will not be publicly available until April 2020.
description: This thesis attempts to distill my experience as a bi-racial, bi-ethnic woman. At the same time these poems explore what it means to be black in contemporary America today. The poems explore themes of rage, injustice, joy and even love. Using plain yet subtle lyrics, I discuss my relationship to the story of my birth, a story I once thought irreparably split. Now having traversed modern explanations of race, these poems chart new growth, new narratives of “wholeness.” All in all, the collection moves from “biological background” in section one, to “conceptual challenge,” in section two, to “emotional freedom” in section three. In total, I argue that the complicated stories of our births need not define the myriad ways we navigate identity, gender, and even physical appearance. For me, this collection is one of intellectual and emotional healing.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Chan Yong Kim, Leong Lum, Wong Hin Yow, Wong Yin Fon, Wong Yin Jor, Sam Man Lee, Jang Yat Yit, Jang Sun Him, Hong Wei, Chun Wan.
title: Combinatorial Trends of Tissue Engineering for Peripheral Nerve Regeneration
Creators: name: Dando, Emma
Publisher: name: George Mason University
Year: 2022
Subjects: subject: Peripheral nerve injury
subject: Tissue engineering

description: Peripheral nerve damage is frequently seen due to injury or illnesses, like diabetes. Despite its prevalence and the fact that many patients with less serious injuries have good clinical outcomes, many patients do not fully recover sensation and in many cases, use of the affected area. For this reason, there has been extensive research into improving or replacing the current treatment options. Many tissue engineering solutions focus on peripheral nerve injury or damage caused specifically by external trauma. The aim of this paper is to list and summarize the primary areas of research for tissue engineering approaches to peripheral nerve regeneration. Moreover, the focus is on the increasing awareness that no single tissue engineering technique is currently capable of providing optimal healing and regeneration for peripheral nerve damage and may never be fully capable of providing complete regeneration. Instead, clinical outcomes may be improved by combining these techniques in multifaceted approaches some of which include combining growth factors and nerve guidance conduits.
Towards Top-Down Just Noticeable Difference Estimation of Natural Images
Creators: name: Jiang, Qiuping
name: Liu, Zhentao
name: Wang, Shiqi
name: Shao, Feng
name: Lin, Weisi
Publisher: name: arXiv
Year: 2021
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Just noticeable difference (JND) of natural images refers to the maximum pixel intensity change magnitude that typical human visual system (HVS) cannot perceive. Existing efforts on JND estimation mainly dedicate to modeling the diverse masking effects in either/both spatial or/and frequency domains, and then fusing them into an overall JND estimate. In this work, we turn to a dramatically different way to address this problem with a top-down design philosophy. Instead of explicitly formulating and fusing different masking effects in a bottom-up way, the proposed JND estimation model dedicates to first predicting a critical perceptual lossless (CPL) counterpart of the original image and then calculating the difference map between the original image and the predicted CPL image as the JND map. We conduct subjective experiments to determine the critical points of 500 images and find that the distribution of cumulative normalized KLT coefficient energy values over all 500 images at these critical points can be well characterized by a Weibull distribution. Given a testing image, its corresponding critical point is determined by a simple weighted average scheme where the weights are determined by a fitted Weibull distribution function. The performance of the proposed JND model is evaluated explicitly with direct JND prediction and implicitly with two applications including JND-guided noise injection and JND-guided image compression. Experimental results have demonstrated that our proposed JND model can achieve better performance than several latest JND models. In addition, we also compare the proposed JND model with existing visual difference predicator (VDP) metrics in terms of the capability in distortion detection and discrimination. The results indicate that our JND model also has a good performance in this task.
description: 16 pages, 16 figures
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Young Kwong Tai, Soo Sik Luon, [Jom Jun Norm], Ng Chun Shing, Wong Soy Poy, Wong Gee, Wong Yun, Leong Norm, Fung Luon Lett, [Gin Sik Wap].
TEXTURAL ANALYSIS OF A ONE-DIMENSIONAL METAL-ORGANIC FRAMEWORK CATENA-[BIS (FORMATO) COPPER (II) DIMETHYLAMINE]N OBTAINED FROM NITROGEN ADSORPTION.
Creators: name: Abdullaev, A.Kh.
name: Yakubov, Y.Y.
name: Ibragimov, A.B.
name: Ruziyev, U.U.
name: Kholto'raev, Q.B.
Publisher: name: Zenodo
Year: 2024

description: The study of nitrogen adsorption properties of porous compounds provides important information about their textural and structural characteristics. The N2 adsorption properties of the newly synthesized MOF are shown in Figure 1. The adsorption isotherm exhibited a steady increase from low to high relative pressure, with a sharp rise as it approached P/P0=1. This indicates the presence of two types of nanopores in the adsorbent: a small amount of micropores and a large amount of mesopores.
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Wong Sing, Ma Lam Hong, Wong Kwong She, [Shun Kun Soy], Lee Dan Hin, Lew Kung Dae, Jay Fun, Lee Hee, Ng Guey, Chin Poy Foon.
Relación de la tercera molar inferior retenida con el conducto del nervio dentario inferior en radiografías panorámicas de la Universidad Católica de Santa María, Arequipa, 2019.
Creators: name: Mamani Hancco, Beisy Flor
Publisher: name: Universidad Católica de Santa María
Year: 2024
Subjects: Tercera molar inferior
Conducto dentario inferior
Radiografía panorámica

description: El objetivo de este estudio fue determinar la relación de las terceras molares inferiores retenidas con el conducto del nervio dentario inferior en radiografías panorámicas de pacientes atendidos en el Centro Odontológico de la Universidad Católica de Santa María, Arequipa 2019. El estudio fue de carácter descriptivo, transversal, retrospectivo y no experimental cuya muestra estuvo conformada por 215 radiografías panorámicas de las cuales se evaluaron 404 piezas dentales. Del total de radiografías panorámicas analizadas se observó en cuanto al sexo, que el 50,7% pertenece al masculino, mientras que 49,3% al sexo femenino. El mayor porcentaje de pacientes que han sido evaluados en este estudio fueron pertenecientes al grupo etáreo de 18 a 28 años con un 46,5 %. El resultado obtenido en las radiografías panorámicas analizadas nos muestra, según la clasificación de Winter, que la posición más frecuente de las terceras molares inferiores retenidas es la vertical con un 37,4 % correspondiente a la hermiarcada derecha y un 35,5 % a la hemiarcada izquierda, seguido de la posición mesiangular con un 34,5 % en la hemiarcada derecha y un 29,4 % en la hemiarcada izquierda, por otro lado la posición horizontal con un 25,2 % en la hemiarcada derecha y un 29,9 % en la hemiarcada izquierda, finalmente la posición invertida se presentó con menos frecuencia con un 2,9 % y 5,1 % en la hemiarcada derecha e izquierda respectivamente. El tipo más frecuente según la clasificación de Pell y Gregory, considerando la profundidad en relación al plano oclusal de la segunda molar inferior de ambas hemiarcadas fue el Tipo A con un 51,5 % para el lado derecho y el 54,8 % para el lado izquierdo. La clase más frecuente según la misma clasificación teniendo en cuenta el diámetro mesiodistal del diente retenido, en relación a la distancia de la segunda molar y la rama mandibular para ambas hemiarcadas fue la Clase II, con un 50 % - 48,2 % para el lado derecho e izquierdo respectivamente. En la presente investigación se pudo determinar que el conducto dentario inferior se encuentra más próximo al reborde alveolar con un 47,9 % siguiendo un trayecto recto en todos los casos evaluados.
Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases
Creators: name: MA Jackson
name: EK Gilding
name: Shafee, Thomas
name: Harris, Karen
name: Q Kaas
name: Poon, Simon
name: K Yap
name: H Jia
name: Guarino, Rosemary
name: LY Chan
name: T Durek
name: Anderson, Marilyn
name: DJ Craik
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2018 The Author(s). Asparaginyl endopeptidases (AEPs) are proteases that have crucial roles in plant defense and seed storage protein maturation. Select plant AEPs, however, do not function as proteases but as transpeptidases (ligases) catalyzing the intra-molecular ligation of peptide termini, which leads to peptide cyclization. These ligase-type AEPs have potential biotechnological applications ranging from in vitro peptide engineering to plant molecular farming, but the structural features enabling these enzymes to catalyze peptide ligation/cyclization rather than proteolysis are currently unknown. Here, we compare the sequences, structures, and functions of diverse plant AEPs by combining molecular modeling, sequence space analysis, and functional testing in planta. We find that changes within the substrate-binding pocket and an adjacent loop, here named the "marker of ligase activity", together play a key role for AEP ligase efficiency. Identification of these structural determinants may facilitate the discovery of more ligase-type AEPs and the engineering of AEPs with tailored catalytic properties.
A Note on Quiver Quantum Toroidal Algebra
Creators: name: Noshita, Go
name: Watanabe, Akimi
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Recently, Li and Yamazaki proposed a new class of infinite-dimensional algebras, quiver Yangian, which generalizes the affine Yangian $\mathfrak{gl}_{1}$. The characteristic feature of the algebra is the action on BPS states for non-compact toric Calabi-Yau threefolds, which are in one-to-one correspondence with the crystal melting models. These algebras can be bootstrapped from the action on the crystals and have various truncations. In this paper, we propose a $q$-deformed version of the quiver Yangian, referred to as the quiver quantum toroidal algebra (QQTA). We examine some of the consistency conditions of the algebra. In particular, we show that QQTA is a Hopf superalgebra with a formal super coproduct, like known quantum toroidal algebras. QQTA contains an extra central charge $C$. When it is trivial ($C=1$), QQTA has a representation acting on the three-dimensional crystals, like Li-Yamazaki's quiver Yangian. While we focus on the toric Calabi-Yau threefolds without compact 4-cycles, our analysis can likely be generalized to all toric Calabi-Yau threefolds.
description: 35+8 pages, 14 figures. v2:typos are fixed and refs added v3:published version
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Wong Yin Joy, Choi Yin Chew, Luey Song, Woo Joon Park, Wong Ying Fat, Leong Yick, Wong Chong, Tsang Wing Ho,Tsang Soo, Lim Chuok Leong.
OIKODOMOS: Experience from pilot studio Grenoble-Bratislava
Creators: name: Joklova, Viera
name: Tucny, Jan
Publisher: name: Zenodo
Year: 2008
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: Architecture
subject: Urban studies
subject: Housing
subject: environmental sustainability
subject: Innovation
subject: Learning
subject: Education
subject: Educational Technology/education

description: This document summarises the experience of the Pilot Studio carried out between the universities of Grenoble and Bratislava.It provides an overview of the pilot studio and of its objectives, and reports on the evaluation of specific items of the studio, namely: Dates, Participants, Target groups, Contents, Actions-aims, Integration in the existing curricula, and Learning outcomes
Canadian Pacific Steamships agent's stubs
Creators: name: Yip Sang Company
name: Canadian Pacific Steamships
Publisher: name: The University of British Columbia
Year: 2016

description: Ticket stubs for the following passengers: Lao Fat, [Lee York], Pon Wei Lung, Pon Gim Lin, Lee Chong Him, Lee Sing Fon, Lee Minig Soon, [Lee Chuck Loy], Dair Chow, Chan Tai Jun.
Predictive modelling of training loads and injury in Australian football
Creators: name: Carey, David
name: Ong, Kok-Leong
name: Whiteley, Rod
name: Crossley, Kay
name: Crow, Justin
name: Morris, Meg
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4207
subject: Sports science and exercise
classificationCode: 46
subject: Information and computing sciences
classificationCode: 4601
subject: Applied computing

description: Abstract: To investigate whether training load monitoring data could be used to predict injuries in elite Australian football players, data were collected from athletes over 3 seasons at an Australian football club. Loads were quantified using GPS devices, accelerometers and player perceived exertion ratings. Absolute and relative training load metrics were calculated for each player each day. Injury prediction models (regularised logistic regression, generalised estimating equations, random forests and support vector machines) were built for noncontact, non-contact time-loss and hamstring specific injuries using the first two seasons of data. Injury predictions were then generated for the third season and evaluated using the area under the receiver operator characteristic (AUC). Predictive performance was only marginally better than chance for models of non-contact and non-contact time-loss injuries (AUC < 0.65). The best performing model was a multivariate logistic regression for hamstring injuries (best AUC=0.76). Injury prediction models built using training load data from a single club showed poor ability to predict injuries when tested on previously unseen data, suggesting limited application as a daily decision tool for practitioners. Focusing the modelling approach on specific injury types and increasing the amount of training observations may improve predictive models for injury prevention.