cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Το "τοπίο" των εμπορικών σημάτων της βιομηχανίας φαρμάκων στην Ελλάδα: γενόσημα έναντι πρωτοτύπων
Creators: name: Τριανταφυλλίδη, Ελένη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Γενόσημα φάρμακα
subject: Εμπορικά σήματα
subject: Φαρμακευτικά εμπορικά σήματα
subject: Καινοτομία

description: Το εμπορικό σήμα συνιστά πολύτιμο άυλο περιουσιακό στοιχείο για μία επιχείρηση. Εφόσον κατοχυρωθεί, θεωρείται νόμιμο δικαίωμα για το δικαιούχο του, ο οποίος έχει τη δυνατότητα αποκλειστικής χρήσης, διάθεσης και μεταβίβασής του. Ταυτόχρονα αποτελεί την ταυτότητα του προϊόντος, αποτρέποντας με τον τρόπο αυτό τη σύγχυση του καταναλωτικού κοινού, ενώ ενισχύει την καινοτομία και την επιχειρηματικότητα. Οι επιχειρήσεις που δραστηριοποιούνται στον κλάδο της φαρμακοβιομηχανίας επενδύουν σημαντικά κεφάλαια για την εμπορική σήμανση των προϊόντων τους, καθώς μέσω αυτής θα πετύχουν την προώθησή αυτών, καθώς και την ενίσχυση της φήμης τους στην αγορά. Ταυτόχρονα ένα σωστά επιλεγμένο φαρμακευτικό εμπορικό σήμα συμβάλλει στην πρόληψη λαθών που μπορεί να προκύψουν από παρόμοιες ονομασίες φαρμάκων, διασφαλίζοντας με τον τρόπο αυτό την προστασία της δημόσιας υγείας. Οι φαρμακευτικές επιχειρήσεις δίνουν ιδιαίτερη έμφαση τόσο στη διαδικασία ονομασίας των προϊόντων τους, όσο και στην κατοχύρωσή τους. Η παρούσα μελέτη στοχεύει στην καταγραφή και ανάλυση δεδομένων που αφορούν στην τρέχουσα κατάσταση καταχώρησης των εμπορικών σημάτων φαρμακευτικών σκευασμάτων –πρωτοτύπων και γενοσήμων- στην Ελλάδα. Τα αποτελέσματα δείχνουν ότι το μεγαλύτερο ποσοστό των φαρμακευτικών εμπορικών σημάτων βρίσκεται σε ενεργό κατοχυρωμένη κατάσταση και χρήση, στοιχείο ενδεικτικό για τη δυναμικότητα που παρουσιάζει ο κλάδος της φαρμακοβιομηχανίας, και ειδικά της παραγωγής γενοσήμων φαρμάκων, στη χώρα μας.
Osmoregulation in zebrafish: ion transport mechanisms and functional regulation
Creators: name: Guh, Ying-Jey
name: Lin, Chia-Hao
name: Hwang, Pung-Pung
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: osmoregulation
subject: ion regulation
subject: ionocyte
subject: hormone
subject: zebrafish
subject: 610

description: Fish, like mammals, have to maintain their body fluid ionic and osmotic homeostasis through sophisticated iono-/osmoregulation mechanisms, which are conducted mainly by ionocytes of the gill (the skin in embryonic stages), instead of the renal tubular cells in mammals. Given the advantages in terms of genetic database availability and manipulation, zebrafish is an emerging model for research into regulatory and integrative physiology. At least five types of ionocytes, HR, NaR, NCC, SLC26, and KS cells, have been identified to carry out Na+ uptake/H+ secretion/NH4+ excretion, Ca2+ uptake, Na+/Cl- uptake, K+ secretion, and Cl- uptake/HCO3- secretion, respectively, through distinct sets of transporters. Several hormones, namely isotocin, prolactin, cortisol, stanniocalcin-1, calcitonin, endothelin-1, vitamin D, parathyorid hormone 1, catecholamines, and the renin-angiotensin-system, have been demonstrated to positively or negatively regulate ion transport through specific receptors at different ionocytes stages, at either the transcriptional/translational or posttranslational level. The knowledge obtained using zebrafish answered many long-term contentious or unknown issues in the field of fish iono-/osmoregulation. The homology of ion transport pathways and hormone systems also means that the zebrafish model informs studies on mammals or other animal species, thereby providing insights into related fields.
description: EXCLI Journal;Vol. 14, 2015
A COMPARISON OF OPTION-THEORETIC AND CHOICE-THEORETIC APPROACHES TO EVALUATING ALTERNATIVE FINANCIAL TECHNOLOGIES FOR MORTGAGE LOANS TO LOW-INCOME HOUSEHOLDS
Creators: name: Hartarska, Valentina M.
name: Gonzalez-Vega, Claudio
name: Hartarska, Valentina M.
name: Gonzalez-Vega, Claudio
Publisher: name: Unknown
Year: 2002
Subjects: subject: Financial Economics
subject: credit counseling
subject: competing risks
subject: low-income mortgage loans.

description: This paper evaluates the efficacy of two alternative lending technologies - the traditional banking technology and a cash flow based counseling program - by using competing risks (option-based) and choice theoretic approaches. We find evidence to support the notion that low-income borrowers have some degree of financial sophistication, as they prepay the mortgage loan by considering the current value of the call option. The evidence also suggests that borrower heterogeneity and insolvency affect mortgage termination.
Microscopic Model for High-spin vs. Low-spin ground state in $[Ni_2{M(CN)_8]}$ ($M=Mo^V, W^V, Nb^{IV}$) magnetic clusters
Creators: name: Raghunathan, Rajamani
name: Sutter, Jean-Pascal
name: Ducasse, Laurent
name: Desplanches, Cedric
name: Ramasesha, S.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Conventional superexchange rules predict ferromagnetic exchange interaction between Ni(II) and M (M=Mo(V), W(V), Nb(IV)). Recent experiments show that in some systems this superexchange is antiferromagnetic. To understand this feature, in this paper we develop a microscopic model for Ni(II)-M systems and solve it exactly using a valence bond approach. We identify the direct exchange coupling, the splitting of the magnetic orbitals and the inter-orbital electron repulsions, on the M site as the parameters which control the ground state spin of various clusters of the Ni(II)-M system. We present quantum phase diagrams which delineate the high-spin and low-spin ground states in the parameter space. We fit the spin gap to a spin Hamiltonian and extract the effective exchange constant within the experimentally observed range, for reasonable parameter values. We also find a region in the parameter space where an intermediate spin state is the ground state. These results indicate that the spin spectrum of the microscopic model cannot be reproduced by a simple Heisenberg exchange Hamiltonian.
description: 8 pages including 7 figures
title: Νοσηρότητα και ασφάλιση υγείας: διαφοροποιήσεις στην Ελλάδα και σε χώρες της Ευρώπης το 2017
title: Morbidity and health insurance schemes: differentiations in Greece and other European countries in 2017
titleType: AlternativeTitle
Creators: name: Τσιάτσιος, Γεώργιος-Άλκης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Νοσηρότητα
subject: Ασφαλιστικό
subject: Ελλάδα

description: Στην παρούσα εργασία μελετήθηκαν, αναλυθήκαν και παρουσιαστήκαν τα συστήματα ασφάλισης στην Ευρώπη. Χρησιμοποιήθηκαν δεδομένα από την βάση δεδομένων SHARE με σκοπό τη βαθύτερη κατανόηση σε κρατικό, ηλικιακό, οικονομικό, κοινωνικό και ασφαλιστικό επίπεδο των κατοίκων της ΕΕ. Μέσω του προγράμματος SPSS δημιουργήθηκαν μοντέλα λογιστικής παλινδρόμησης από τα οποία βγήκαν ενδιαφέροντα συμπεράσματα που παρουσιάζουν την σχέση των ασφαλιστικών προϊόντων και της νοσηρότητας για την Ελλάδα και την Ευρώπη. Η ανάλυση θα γίνει ανάλογα το φύλο, την ηλικία, την χώρα εκπαίδευσης καθώς και την ικανότητα κάθε νοικοκυριού να περάσει την οικονομική χρονιά.
Persimmon (Diospyros kaki) fruit: hidden phytochemicals and health claims
Creators: name: Butt, Masood Sadiq
name: Sultan, M. Tauseef
name: Aziz, Mahwish
name: Naz, Ambreen
name: Ahmed, Waqas
name: Kumar, Naresh
name: Imran, Muhammad
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: Persimmon
subject: phytochemicals
subject: astringency
subject: tannins
subject: cardiovascular disorders
subject: oxidative stress
subject: diabetes mellitus
subject: 610

description: Currently, nutrition and health linkages focused on emerging strategy of diet based regimen to combat various physiological threats including cardiovascular disorders, oxidative stress, diabetes mellitus, etc. In this context, consumption of fruits and vegetables is gaining considerable importance as safeguard to maintain human health. Likewise, their phytochemicals and bioactive molecules are also becoming popular as promising demulcent against various ailments. The current review is an effort to sum up information regarding persimmon fruit with special reference to its phytochemistry and associated health claims. Accordingly, the role of its certain bioactive molecules like proanthocyanidin, carotenoids, tannins, ﬂavonoids, anthocyanidin, catechin, etc. is highlighted. Owing to rich phytochemistry, persimmon and its products are considered effective in mitigating oxidative damage induced by reactive oxygen species (ROS). The antioxidant potential is too responsible for anti-malignant and anti-melanogenic perspectives of persimmon functional ingredients. Additionally, they are effectual in soothing lifestyle related disparities e.g. cardiovascular disorders and diabetes mellitus. There are proven facts that pharmacological application of persimmon or its functional ingredients like proanthocyanidin may helps against hyperlipidemia and hyperglycemia. Nevertheless, astringent taste and diospyrobezoars formation are creating lacuna to prop up its vitality. In toto, persimmon and its components hold potential as one of effective modules in diet based therapy; however, integrated research and meta-analysis are still required to enhance meticulousness.
description: EXCLI Journal;Vol. 14, 2015
AN EMPIRICAL EVALUATION OF THE CANADIAN WHEAT BOARD'S ABILITY TO PRICE DISCRIMINATE IN BREAD WHEAT EXPORTS.
Creators: name: Lavoie, Nathalie
name: Lavoie, Nathalie
Publisher: name: Unknown
Year: 2002
Subjects: International Relations/Trade

description: This study examines the ability of the Canadian Wheat Board (CWB) to price discriminate in bread wheat exports. The conceptual model isolates the bases of price discrimination and demonstrates that the CWB's ability to exploit cost differences in pricing depends on the extent of the differentiation between Canadian and U.S. wheat. This model is implemented using monthly confidential price data provided by the CWB for exports to Japan, the United Kingdom, and two markets aggregating remaining exports through Canada's west and east coasts, for 1982-1994. The data indicate that the CWB charges different prices to different countries for wheat of the same grade and protein content. Results from the model indicate that the price difference between any two markets is not completely explained by elements of perfect competition. However, the evidence is mixed regarding the ability of the CWB to utilize all the instruments available to price discriminate. Thus, the CWB's pricing strategy may be more complex and dynamic than the prescription for static producer surplus maximization derived in this study.
Role of anti-diabetic drugs as therapeutic agents in Alzheimer's disease
Creators: name: Rizvi, Syed Mohd. Danish
name: Shaikh, Sibhghatulla
name: Waseem, Shah Mohammad Abbas
name: Shakil, Shazi
name: Abuzenadah, Adel M.
name: Biswas, Deboshree
name: Tabrez, Shams
name: Ashraf, Ghulam Md.
name: Kamal, Mohammad Amjad
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: Alzheimer’s disease
subject: anti-diabetic drugs
subject: amyloid beta
subject: beta-secretase
subject: sodium glucose
subject: co-transporters
subject: Type 2 Diabetes Mellitus
subject: 610

description: Recent data have suggested a strong possible link between Type 2 Diabetes Mellitus and Alzheimer’s disease (AD), although exact mechanisms linking the two are still a matter of research and debate. Interestingly, both are diseases with high incidence and prevalence in later years of life. The link appears so strong that some scientists use Alzheimer’s and Type 3 Diabetes interchangeably. In depth study of recent data suggests that the anti diabetic drugs not only have possible role in treatment of Alzheimer’s but may also arrest the declining cognitive functions associated with it. The present review gives an insight into the possible links, existing therapeutics and clinical trials of anti diabetic drugs in patients suffering from AD primarily or as co-morbidity. It may be concluded that the possible beneficial effects and usefulness of the current anti diabetic drugs in AD cannot be neglected and further research is required to achieve positive results. Currently, several drug trials are in progress to give conclusive evidence based data.
description: EXCLI Journal;Vol. 14, 2015
Corrections of Errors in `The First Detections of the Extragalactic Background Light at 3000, 5500, and 8000 Å. I, II, and III'
Creators: name: Bernstein, R. A.
name: Freedman, W. L.
name: Madore, B. F.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We correct errors in Bernstein, Freedman & Madore (2002abc), a series of papers in which we described observations of the optical extragalactic background light (EBL). These errors pertain to the measurement of zodiacal light, given in the second paper of this series. Making these corrections leads to a net decrease of 0.5($\pm$0.6)% in our zodiacal light measurement and a corresponding increase in the inferred extragalactic background light of roughly $0.5 (\pm 0.6) \times 10^{-9}$ ergs sec$^{-1}$ cm$^{-2}$ sr$^{-1}$ Å$^{-1}$. For comparison, the originally--quoted EBL flux at 5500Åwas $2.7 (\pm1.4) \times 10^{-9}$ in the same units ($1σ$ combined systematic and statistical uncertainty). We provide a detailed discussion of these errors and also discuss the evolution of this work prior to the (2002) papers. We note that corrections of the factual errors in our (2002) papers yield a result that is consistent with the results and errors quoted there. However, this is not intended to be a new or updated analysis, and it does not address some methodological objections which have been raised to our prior work.
description: Accepted for publication in ApJ
Constraining cosmology with weak lensing voids
Creators: name: Davies, Christopher T.
name: Cautun, Marius
name: Giblin, Benjamin
name: Li, Baojiu
name: Harnois-Déraps, Joachim
name: Cai, Yan-Chuan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Upcoming surveys such as \LSST{} and \Euclid{} will significantly improve the power of weak lensing as a cosmological probe. To maximise the information that can be extracted from these surveys, it is important to explore novel statistics that complement standard weak lensing statistics such as the shear-shear correlation function and peak counts. In this work, we use a recently proposed weak lensing observable -- weak lensing voids -- to make parameter constraint forecasts for an LSST-like survey. We use the \cosmoslics{} $w$CDM simulation suite to measure void statistics as a function of cosmological parameters. The simulation data is used to train a Gaussian process regression emulator that we use to generate likelihood contours and provide parameter constraints from mock observations. We find that the void abundance is more constraining than the tangential shear profiles, though the combination of the two gives additional constraining power. We forecast that without tomographic decomposition, these void statistics can constrain the matter fluctuation amplitude, $S_8$ within 0.3\% (68\% confidence interval), while offering 1.5, 1.5 and 2.7\% precision on the matter density parameter, $Ω_{\rm m}$, the reduced Hubble constant, $h$, and the dark energy equation of state parameter, $w_0$, respectively. These results are tighter than the constraints from the shear-shear correlation function with the same observational specifications for $Ω_m$, $S_8$ and $w_0$. The constraints from the WL voids also have complementary parameter degeneracy directions to the shear 2PCF for all combinations of parameters that include $h$, making weak lensing void statistics a promising cosmological probe.
description: 12 pages, 8 figures, accepted by MNRAS
Plants with potential use on obesity and its complications
Creators: name: Gamboa-Gómez, Claudia I.
name: Rocha-Guzmán, Nuria E.
name: Gallegos-Infante, J. Alberto
name: Moreno-Jiménez, Martha R.
name: Vázquez-Cabral, Blanca D.
name: González-Laredo, Rubén F.
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: obesity
subject: obesity complications
subject: anti-obesity plants
subject: phytochemicals
subject: alternative treatments
subject: 610

description: Obesity is the most prevalent nutritional disease and a growing public health problem worldwide. This disease is a causal component of the metabolic syndrome related with abnormalities, including hyperglycemia, dyslipidemia, hypertension, inflammation, among others. There are anti-obesity drugs, affecting the fundamental processes of the weight regulation; however they have shown serious side effects, which outweigh their beneficial effects. Most recent studies on the treatment of obesity and its complications have focused on the potential role of different plants preparation that can exert a positive effect on the mechanisms involved in this pathology. For instance, anti-obesity effects of green tea and its isolated active principles have been reported in both in vitro (cell cultures) and in vivo (animal models) that possess healthy effects, decreasing adipose tissue through reduction of adipocytes differentiation and proliferation. A positive effect in lipid profile, and lipid and carbohydrates metabolisms were demonstrated as well. In addition, anti-inflammatory and antioxidant activities were studied. However, the consumption of green tea and its products is not that common in Western countries, where other plants with similar bioactivity predominate; nevertheless, the effect extension has not been analyzed in depth, despite of their potential as alternative treatment for obesity. In this review the anti-obesity potential and reported mechanisms of action of diverse plants such as: Camellia sinensis, Hibiscus sabdariffa, Hypericum perforatum, Persea americana, Phaseolus vulgaris, Capsicum annuum, Rosmarinus officinalis, Ilex paraguariensis, Citrus paradisi, Citrus limon, Punica granatum, Aloe vera, Taraxacum officinale and Arachis hypogaea is summarized. We consider the potential of these plants as natural alternative treatments of some metabolic alterations associated with obesity.
description: EXCLI Journal;Vol. 14, 2015
Vonhoff, Heinz: Die Geschichte der Kirche im Unterricht der Schule
Creators: name: Thelemann, Hans-Martin
Publisher: name: Ökumenische Rundschau
Year: 2025

description: Ökumenische Rundschau, Bd. 18 Nr. 2 (1969): Ökumenische Rundschau, Band 18, Heft 2
Analytical approach to the quantum-phase transition in the one-dimensional spinless Holstein model
Creators: name: Sykora, S.
name: Huebsch, A.
name: Becker, K. W.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the one-dimensional Holstein model of spinless fermions interacting with dispersion-less phonons by using a recently developed projector-based renormalization method (PRM). At half-filling the system shows a metal-insulator transition to a Peierls distorted state at a critical electron-phonon coupling where both phases are described within the same theoretical framework. The transition is accompanied by a phonon softening at the Brillouin zone boundary and a gap in the electronic spectrum. For different filling, the phonon softening appears away from the Brillouin zone boundary and thus reflects a different type of broken symmetry state.
description: 8 pages, 4 figures included; v2: completely revised and extended; v3: minor changes, final version, to be published in Eur. Phys. J. B
Τέχνη και μάνατζμεντ - Σαίξπηρ και ηγεσία
Creators: name: Μουστάκας, Ιωάννης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ηγεσία
subject: Ουίλλιαμ Σαίξπηρ
subject: Τέχνη
subject: Μάνατζμεντ
subject: Ιούλιος Καίσαρας
subject: Ερρίκος Ε'
subject: Ριχάρδος Γ'
subject: Μάκβεθ
subject: Βρούτος
subject: Εξουσία
subject: Μετασχηματιστική ηγεσία
subject: Ψευδομετασχηματιστική ηγεσία
subject: Συναλλακτική ηγεσία

description: Η θεωρία ηγεσίας είναι ένα πολύ σημαντικό κομμάτι της επιστήμης του μάνατζμεντ. Τις τελευταίες δεκαετίες, οι ερευνητές ασχολούνται όλο και περισσότερο με αυτό το πεδίο και η βιβλιογραφία έχει αυξηθεί σημαντικά. Μία από τις μοντέρνες και πιο δημοφιλείς προσεγγίσεις αποτελεί το μοντέλο της μετασχηματιστικής ηγεσίας, όπως το διατύπωσε ο Burns το 1978 και το οποίο συνεχίζει να απασχολεί τους επιστήμονες του κλάδου μέχρι και σήμερα. Από τη μία, λοιπόν, η μετασχηματιστική ηγεσία. Από την άλλη ο Ουίλιαμ Σαίξπηρ, ο μεγάλος Άγγλος θεατρικός συγγραφέας. Το μεγαλύτερο κομμάτι των θεατρικών έργων του πραγματεύεται σχέσεις εξουσίας και την άσκησή της από τους ηγέτες, είτε σε μοναρχικά καθεστώτα είτε σε πρώιμες και μάλλον άγουρες δημοκρατικές κοινωνίες. Κύριος στόχος της εργασίας είναι η εύρεση ηγετών ανάμεσα στους χαρακτήρες του Σαίξπηρ, των οποίων τα προσωπικά χαρακτηριστικά στοιχεία, ο τρόπος με τον οποίον ασκούν ηγεσία και οι συμπεριφορές τους αντιστοιχούν στο μοντέλο της μετασχηματιστικής ηγεσίας. Τα ευρήματα από την ανάλυση των τεσσάρων έργων που επιλέχθηκαν αναδεικνύουν δύο μετασχηματιστικούς, έναν συναλλακτικό και έναν ψευδομετασχηματιστικό ηγέτη. Αυτό υποστηρίζει και τη θέση ότι συνολικά η τέχνη και εν προκειμένω τα έργα του Ουίλιαμ Σαίξπηρ, μπορούν να αποτελέσουν πηγή μελέτης και πεδίο έρευνας για τον επιστημονικό κλάδο της ηγεσίας και γενικότερα του μάνατζμεντ, προσφέροντας πλούσια συμπεράσματα.
THE CHOICE OF THE SUPPLY CHANNELS IN HUNGARIAN FRUIT AND VEGETABLE SECTOR
Creators: name: Ferto, Imre
name: Szabo, Gabor G.
name: Ferto, Imre
name: Szabo, Gabor G.
Publisher: name: Unknown
Year: 2002
Subjects: subject: Marketing
subject: FOS: Economics and business

description: The agricultural reform in Hungary broke the previously vertically integrated agri-food system in different lines. The structures in agriculture, food industry and food retailing have fundamentally changed. These changes have also influenced the vertical governance structures in agri-food sector. The aim of this paper is to investigate the choice of farmers among various supply channels in Hungarian fruit and vegetable sector employing the framework of transaction cost economics. Our analysis is based on a survey among fruit and vegetable producers in Csongrád county in respect the choice of marketing channels. A multinomial logit model is applied to reveal on the determinants influencing the choice among various supply channels. The results seem to contradict some of the basic propositions of transaction cost economics.
The ICECUBE prototype string in AMANDA
Creators: name: AMANDA Collaboration
name: Ackermann, M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Antarctic Muon And Neutrino Detector Array (Amanda) is a high-energy neutrino telescope. It is a lattice of optical modules (OM) installed in the clear ice below the South Pole Station. Each OM contains a photomultiplier tube (PMT) that detects photons of Cherenkov light generated in the ice by muons and electrons. IceCube is a cubic-kilometer-sized expansion of Amanda currently being built at the South Pole. In IceCube the PMT signals are digitized already in the optical modules and transmitted to the surface. A prototype string of 41 OMs equipped with this new all-digital technology was deployed in the Amanda array in the year 2000. In this paper we describe the technology and demonstrate that this string serves as a proof of concept for the IceCube array. Our investigations show that the OM timing accuracy is 5 ns. Atmospheric muons are detected in excellent agreement with expectations with respect to both angular distribution and absolute rate.
A High-Order Accurate Meshless Method for Solution of Incompressible Fluid Flow Problems
Creators: name: Shahane, Shantanu
name: Radhakrishnan, Anand
name: Vanka, Surya Pratap
Publisher: name: arXiv
Year: 2020
Subjects: subject: Numerical Analysis (math.NA)
subject: Computational Physics (physics.comp-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Meshless solution to differential equations using radial basis functions (RBF) is an alternative to grid based methods commonly used. Since the meshless method does not need an underlying connectivity in the form of control volumes or elements, issues such as grid skewness that adversely impact accuracy are eliminated. Gaussian, Multiquadrics and inverse Multiquadrics are some of the most popular RBFs used for the solutions of fluid flow and heat transfer problems. But they have additional shape parameters that have to be fine tuned for accuracy and stability. Moreover, they also face stagnation error when the point density is increased for accuracy. Recently, Polyharmonic splines (PHS) with appended polynomials have been shown to solve the above issues and give rapid convergence of discretization errors with the degree of appended polynomials. In this research, we extend the PHS-RBF method for the solution of incompressible Navier-Stokes equations. A fractional step method with explicit convection and explicit diffusion terms is combined with a pressure Poisson equation to satisfy the momentum and continuity equations. Systematic convergence tests have been performed for five model problems with two of them having analytical solutions. We demonstrate fast convergence both with refinement of number of points and degree of appended polynomials. The method is further applied to solve problems such as lid-driven cavity and vortex shedding over circular cylinder. We have also analyzed the performance of this approach for solution of Euler equations. The proposed method shows promise to solve fluid flow and heat transfer problems in complex domains with high accuracy.
Mesoscopic Theory of Critical Fluctuations in Isolated Granular Gases
Creators: name: Brey, J. Javier
name: Dominguez, A.
name: de Soria, M. I. Garcia
name: Maynar, P.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Fluctuating hydrodynamics is used to describe the total energy fluctuations of a freely evolving gas of inelastic hard spheres near the threshold of the clustering instability. They are shown to be governed by vorticity fluctuations only, that also lead to a renormalization of the average total energy. The theory predicts a power-law divergent behavior of the scaled second moment of the fluctuations, and a scaling property of their probability distribution, both in agreement with simulations results. A more quantitative comparison between theory and simulation for the critical amplitudes and the form of the scaling function is also carried out.
Pharmaceutical sector price and productivity measurement : exploring the role of agency, incentives and information
Creators: name: Morgan, Steven George
Publisher: name: University of British Columbia
Year: 2009

description: This thesis explores how decision-making agency roles played by doctors, pharmacists and government affect the social efficiency of choices in the prescription drug market. The primary objective is to contribute to the quality of expenditure decompositions in this sector and, thereby, to draw attention to the real cost of drug consumption in Canada. Expenditure growth in the pharmaceutical sector may occur because Canadians are purchasing more drugs or more in terms of the health outcomes sought through drug consumption. Prices may also be rising for the drugs that patients consume. Furthermore, with new generations of prescription drugs replacing older and often equally effective ones, expenditure inflation may be due, at least in part, to growing inefficiencies in consumption. Deflating nominal expenditures with traditional economic price indexes is a commonly used approach to decomposing expenditure changes into changes in price, changes in productivity or both. This method may be biased because decision-making agency relationships and non-standard financial incentives give rise to possible inefficiencies in the pharmaceutical sector that would not commonly be found in other sectors. This proposition is explored theoretically and empirically. Potential biases stemming from financial incentives are explored in the context of the measurement problem posed by the entry of generic drugs. Traditional techniques of the economic approach to measurement do not capture the full effect of generic competition because decision-making agents do not always have incentive to consider the full price of drugs consumed. Potential information-related problems in pharmaceutical price and productivity measurement are explored within the context of the hypertension market. Health outcomes based indexes are constructed for this treatment category based on recognized national guidelines for the treatment of hypertension. Economic indexes of price and productivity appear to overstate social productivity in this segment because persistent non-compliance with national guidelines has resulted in higher costs without corresponding health improvements.
Διερεύνηση των αναπτυξιακών προοπτικών μιας ανταγωνιστικής συστάδας επιχειρήσεων στην ευρύτερη περιοχή του Βοτανικού - Ελαιώνα
Creators: name: Γεωργούλας, Δημήτριος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Μεταφορική συστάδα
subject: Ελαιώνας
subject: Ανταγωνιστικότητα
subject: Συστάδα
subject: Logistics

description: Η Ελλάδα επιχειρεί τα τελευταία χρόνια να αναδείξει το διαμετακομιστικό της χαρακτήρα και να ενισχύσει την ανταγωνιστικότητά της διεθνώς. Σε αυτά τα πλαίσια και εκμεταλλευόμενοι ένα πρώην Βιομηχανικό Πάρκο που ενώ βιώνει την υποβάθμιση τις τελευταίες δεκαετίες, έχει αναπτύξει μια ταυτότητα που σχετίζεται με τον τομέα της οδικής μεταφοράς, πραγματοποιήθηκε η παρούσα έρευνα με σκοπό να εντοπιστούν οι προϋποθέσεις και οι ελλείψεις που υφίστανται για να σχηματιστεί στην περιοχή ένα μεταφορικό cluster. Η μελέτη διήρκησε 6 μήνες και ολοκληρώθηκε μέσα από την ανάλυση των απόψεων των επιχειρηματιών. Αρχικά πραγματοποιήθηκαν συνεντεύξεις για τη σύνταξη ερωτηματολογίου, το οποίο διανεμήθηκε ηλεκτρονικά στις επιχειρήσεις της περιοχής ενώ στη συνέχεια πραγματοποιήθηκαν συνεντεύξεις με σκοπό την πιο ολοκληρωμένη ανάλυση των αποτελεσμάτων του ερωτηματολογίου. Η έρευνα κατέληξε στο ότι στην περιοχή του Βοτανικού-Ελαιώνα αν και δεν υπάρχει θεσμοθετημένη συστάδα, υπάρχουν αρκετά στοιχεία όπως δομή και διακυβέρνηση μιας συστάταδας που καλλιεργούν ένα ευνοϊκό κλίμα για μελλοντική συγκρότησή της. Ωστόσο, εντοπίστηκαν και βασικές ελλείψεις στην περιοχή όπως οι φυσικές υποδομές και η απουσία συνεργασίας των τοπικών επιχειρήσεων με εκπαιδευτικά ιδρύματα, για τα οποία συντάχθηκαν προτάσεις.
ARE THERE SYNERGIES OR TRADEOFFS BETWEEN ARTICLES AND PATENTS IN UNIVERSITY AG-BIOTECH RESEARCH
Creators: name: Kim, Kwansoo
name: Foltz, Jeremy D.
name: Barham, Bradford L.
name: Kim, Kwansoo
name: Foltz, Jeremy D.
name: Barham, Bradford L.
Publisher: name: Unknown
Year: 2002
Subjects: Research and Development/Tech Change/Emerging Technologies

description: This paper examines the empirical evidence for synergies or tradeoffs associated with the rapid rise of ag-biotech patenting at Land Grant Universities by examining the question of whether journal articles and patents appear to be complementary or competing activities in agricultural biotechnology research. The results show many synergies and none of the expected tradeoffs between the basic research represented in journal articles and the commercial proprietary research represented in patents.
Βέλτιστη στρατηγική επανεπένδυσης και υπολογισμός εταιρικής ανάπτυξης
Creators: name: Πανουργιάς, Μιχάλης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Real options
subject: Εταιρική ανάπτυξη
subject: Παράγωγα προϊόντα
subject: Μέθοδος επανεπένδυσης

description: Στην εργασία αυτή θα παρουσιάσουμε τον τρόπο με τον οποίο οι χρηματοπιστωτικοί οργανισμοί και εταιρείες μπορούν να εφαρμόσουν μια βέλτιστη στρατηγική επένδυσης, αλλά και επανεπένδυσης, των περιουσιακών τους στοιχείων με απώτερο στόχο την αύξηση των πωλήσεων τους και κατά επέκταση την εταιρική τους ανάπτυξη. Το προτεινόμενο μοντέλο που θα αναλύσουμε, υπολογίζει και διαχειρίζει τις μελλοντικές ταμειακές ροές που θα προκύψουν από επενδύσεις σε εξοπλισμό και περιουσιακά στοιχεία μέσω της χρήσης των χρηματοοικονομικών παραγώγων και πιο συγκεκριμένα των δικαιωμάτων προαίρεσης. Θα παρουσιάσουμε τις διάφορες καταστάσεις και θέσεις που μπορεί να πάρει μια εταιρεία προσπαθώντας να βρει τη βέλτιστη στρατηγική που θα εφαρμόσει, καθώς και τρόπους τιμολόγησης και αποτίμησης των δικαιωμάτων προαίρεσης που αποτελούν τον βασικό πυλώνα της εταιρείας σε αυτή της την προσπάθεια. Επίσης, θα αναλύσουμε διάφορα στοχαστικά μοντέλα και μεθόδους που μας βοηθάνε στην αποτίμηση των χρηματοοικονομικών παραγώγων και τέλος, θα παρουσιάσουμε τα συμπεράσματα που πηγάζουν από αυτό το μοντέλο και ποια θέση θα πρέπει να πάρει η εταιρεία για να επιτύχει το βέλτιστο αποτέλεσμα.
Το οργανωσιακό κλίμα και η ένταξη των νέων εκπαιδευτικών στο σχολείο
Creators: name: Κρητικάκου, Παναγιώτα
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Οργανωσιακό κλίμα
subject: Οργανωσιακή κουλτούρα
subject: Ένταξη
subject: Νέοι εκπαιδευτικοί
subject: Επαγγελματική ανάπτυξη
subject: Έρευνα

description: Εάν κάθε άτομο μέσα σε μια οργανωτική κουλτούρα και κλίμα αντιμετωπίζεται όσο το δυνατόν θετικότερα, τότε και αυτό το άτομο με τη σειρά του, μπορεί να ωθήσει τους άλλους να προσφέρουν στον οργανισμό και στα ενδιαφερόμενα μέρη του το καλύτερο δυνατό. Η ένταξη μπορεί να θεωρηθεί ως η αντανάκλαση της κουλτούραςπου επικρατεί τόσο για το πώς οι εκπαιδευτικοί μαθαίνουν για τη διδασκαλία όσο και για το τι περιλαμβάνει η διδασκαλία. Επιπλέον, ο στόχος της ένταξης είναι η βελτίωση της απόδοσης και της διατήρησης των νέων εκπαιδευτικών, δηλαδή, τόσο για την ενίσχυση όσο και για την πρόληψη της απώλειας ανθρώπινου κεφαλαίου των εκπαιδευτικών, με απώτερο στόχο τη βελτίωση της ανάπτυξης και της μάθησης των μαθητών. Μέσα από όλη τη βιβλιογραφία των ζητημάτων για την οργανωτική κουλτούρα και την ένταξη, διαπιστώνεται η αλληλεπίδρασή τους, η συσχέτισή τους και το γεγονός ότι αποτελούν καθοριστικούς παράγοντες για την επαγγελματική ανάπτυξη ενός νέου εκπαιδευτικού. Σκοπός αυτής της εργασίας είναι να αναδείξει τα σημαντικότερα σημεία της βιβλιογραφίας σχετικά με αυτά τα ζητήματα και να διαπιστώσει μέσω ποσοτικής έρευνας με χρήση ερωτηματολογίου σε νεοδιόριστους εκπαιδευτικούς, το επίπεδο στο οποίο οι ελληνικές σχολικές μονάδες εφαρμόζουν τις πιο σύγχρονες αντιλήψεις σχετικά με αυτά καθώς και να επιβεβαιώσει τη συσχέτιση μεταξύ του κλίματος, της ένταξης και της επαγγελματικής ανάπτυξης.
Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axis
Creators: name: Asri, Amir
name: Sabour, Javid
name: Atashi, Amir
name: Soleimani, Masoud
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: CXCR7
subject: CXCR4
subject: CXCL12
subject: HSCs homing
subject: 610

description: Hematopoietic stem cells (HSCs) form a rare population of multipotent stem cells, which give rise to all hematopoietic lineages. HSCs home to bone marrow niches and circulate between blood and bone marrow. Many factors, especially SDF1a, affect the circulation of HSCs, but these have not been fully recognized. SDF1a has been shown to bind CXCR7 in addition to CXCR4 and can also function as SDF1a/CXCR4 modulator. CXCR7 plays a role in HSCs homing via SDF1a gradient and is a mediator of CXCR4/SDF1a axis. This review describes the current concepts and questions concerning CXCR7/CXCR4/SDF1a axis as an important key in hematopoietic stem cells homing with particular emphasis on CXCR7 receptor. Homing of HSCs is an essential step for successful hematopoietic stem cell transplantation.
description: EXCLI Journal;Vol. 15, 2016
EX POST MORAL HAZARD IN CROP INSURANCE: COSTLY STATE VERIFICATION OR FALSIFICATION?
Creators: name: Rejesus, Roderick M.
name: Rejesus, Roderick M.
Publisher: name: Unknown
Year: 2002
Subjects: Risk and Uncertainty

description: This article examines the extent to which actual crop insurance indemnification behavior conforms to the theoretical predictions of two ex post moral hazard models - costly state verification and costly state falsification. A nonparametric regression technique is used to estimate the crop insurance indemnification profile for non-irrigated cotton in Texas. The results suggest that indemnification behavior in crop insurance is more in line with the costly state falsification paradigm. Thus, crop insurers seem to indemnify based on the assumption that it is not easy to verify actual ex post loss magnitude and eliminate the asymmetric information held by the insured farmers.
Filtering in tractography using autoencoders (FINTA)
Creators: name: Legarreta, Jon Haitz
name: Petit, Laurent
name: Rheault, François
name: Theaud, Guillaume
name: Lemaire, Carl
name: Descoteaux, Maxime
name: Jodoin, Pierre-Marc
Publisher: name: arXiv
Year: 2020
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Neurons and Cognition (q-bio.NC)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences
subject: I.5.1; J.3
subject: 62M20, 62M45, 68T01, 68U10, 92C55

description: Current brain white matter fiber tracking techniques show a number of problems, including: generating large proportions of streamlines that do not accurately describe the underlying anatomy; extracting streamlines that are not supported by the underlying diffusion signal; and under-representing some fiber populations, among others. In this paper, we describe a novel autoencoder-based learning method to filter streamlines from diffusion MRI tractography, and hence, to obtain more reliable tractograms. Our method, dubbed FINTA (Filtering in Tractography using Autoencoders) uses raw, unlabeled tractograms to train the autoencoder, and to learn a robust representation of brain streamlines. Such an embedding is then used to filter undesired streamline samples using a nearest neighbor algorithm. Our experiments on both synthetic and in vivo human brain diffusion MRI tractography data obtain accuracy scores exceeding the 90\% threshold on the test set. Results reveal that FINTA has a superior filtering performance compared to conventional, anatomy-based methods, and the RecoBundles state-of-the-art method. Additionally, we demonstrate that FINTA can be applied to partial tractograms without requiring changes to the framework. We also show that the proposed method generalizes well across different tracking methods and datasets, and shortens significantly the computation time for large (>1 M streamlines) tractograms. Together, this work brings forward a new deep learning framework in tractography based on autoencoders, which offers a flexible and powerful method for white matter filtering and bundling that could enhance tractometry and connectivity analyses.
description: Preprint. Published in Medical Image Analysis 72 (2021) 102126
Generating semantic maps through multidimensional scaling: linguistic applications and theory
Creators: name: van der Klis, Martijn
name: Tellings, Jos
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: This paper reports on the state-of-the-art in application of multidimensional scaling (MDS) techniques to create semantic maps in linguistic research. MDS refers to a statistical technique that represents objects (lexical items, linguistic contexts, languages, etc.) as points in a space so that close similarity between the objects corresponds to close distances between the corresponding points in the representation. We focus on the use of MDS in combination with parallel corpus data as used in research on cross-linguistic variation. We first introduce the mathematical foundations of MDS and then give an exhaustive overview of past research that employs MDS techniques in combination with parallel corpus data. We propose a set of terminology to succinctly describe the key parameters of a particular MDS application. We then show that this computational methodology is theory-neutral, i.e. it can be employed to answer research questions in a variety of linguistic theoretical frameworks. Finally, we show how this leads to two lines of future developments for MDS research in linguistics.
description: 40 pages; pre-print; accepted for publication in Corpus Linguistics & Linguistic Theory (Nov. 2021)
Connection Pruning for Deep Spiking Neural Networks with On-Chip Learning
Creators: name: Nguyen, Thao N. N.
name: Veeravalli, Bharadwaj
name: Fong, Xuanyao
Publisher: name: arXiv
Year: 2020
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Long training time hinders the potential of the deep, large-scale Spiking Neural Network (SNN) with the on-chip learning capability to be realized on the embedded systems hardware. Our work proposes a novel connection pruning approach that can be applied during the on-chip Spike Timing Dependent Plasticity (STDP)-based learning to optimize the learning time and the network connectivity of the deep SNN. We applied our approach to a deep SNN with the Time To First Spike (TTFS) coding and has successfully achieved 2.1x speed-up and 64% energy savings in the on-chip learning and reduced the network connectivity by 92.83%, without incurring any accuracy loss. Moreover, the connectivity reduction results in 2.83x speed-up and 78.24% energy savings in the inference. Evaluation of our proposed approach on the Field Programmable Gate Array (FPGA) platform revealed 0.56% power overhead was needed to implement the pruning algorithm.
description: 8 pages, 9 figures This paper has been accepted for publication in the International Conference on Neuromorphic Systems (ICONS) 2021
Towards soliton solutions of a perturbed sine-Gordon equation
Creators: name: D'Anna, Armando
name: De Angelis, Monica
name: Fiore, Gaetano
Publisher: name: arXiv
Year: 2005
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 35Q51, 37K45

description: We give arguments for the existence of {\it exact} travelling-wave (in particular solitonic) solutions of a perturbed sine-Gordon equation on the real line or on the circle, and classify them. The perturbation of the equation consists of a constant forcing term and a linear dissipative term. Such solutions are allowed exactly by the energy balance of these terms, and can be observed experimentally e.g. in the Josephson effect in the theory of superconductors, which is one of the physical phenomena described by the equation.
description: 16 pages, 4 figures included
THE EFFECT OF TRUST ON PUBLIC SUPPORT FOR BIOTECHNOLOGY: EVIDENCE FROM THE U.S. BIOTECHNOLOGY STUDY, 1997-1998
Creators: name: James, Harvey S.
name: James, Harvey S.
Publisher: name: Unknown
Year: 2002
Subjects: Research and Development/Tech Change/Emerging Technologies

description: The purpose of this paper is to examine the extent to which trust directly affects public support for biotechnology, particularly in applications to food production and genetic modification of crop plants. Unlike previous research in which trust is assumed to be exogenous, this paper posits that trust is endogenously determined. An econometric model is developed that controls for the endogeneity of trust using instrumental variable and selection correction techniques. Using data from the U.S. Biotechnology Study, this study finds that the effect of trust on public support is substantially stronger than previous estimates.
Evaluation of glucose-6-phosphate dehydrogenase stability in stored blood samples
Creators: name: Jalil, Norunaluwar
name: Azma, Raja Zahratul
name: Mohamed, Emida
name: Ithnin, Azlin
name: Alauddin, Hafiza
name: Baya, Siti Noor
name: Othman, Ainoon
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: G6PD stability
subject: G6PD enzyme assay
subject: OSMMR2000-D G6PD Assay Kit
subject: EDTA
subject: dried blood spot
subject: 610

description: Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is the commonest cause of neonatal jaundice in Malaysia. Recently, OSMMR2000-D G6PD Assay Kit has been introduced to quantitate the level of G6PD activity in newborns delivered in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). As duration of sample storage prior to analysis is one of the matters of concern, this study was conducted to identify the stability of G6PD enzyme during storage. A total of 188 cord blood samples from normal term newborns delivered at UKMMC were selected for this study. The cord bloods samples were collected in ethylene-diamine-tetra-acetic acid (EDTA) tubes and refrigerated at 2-8 °C. In addition, 32 out of 188 cord blood samples were spotted on chromatography paper, air-dried and stored at room temperature. G6PD enzyme activities were measured daily for 7 days using the OSMMR2000-D G6PD Assay Kit on both the EDTA blood and dried blood samples. The mean value for G6PD activity was compared between days of analysis using Student Paired T-Test. In this study, 172 out of 188 cord blood samples showed normal enzyme levels while 16 had levels corresponding to severe enzyme deficiency. The daily mean G6PD activity for EDTA blood samples of newborns with normal G6PD activity showed a significant drop on the fourth day of storage (p < 0.005) while for samples with severely deficient G6PD activity, significant drop was seen on third day of storage (p = 0.002). Analysis of dried cord blood showed a significant reduction in enzyme activity as early as the second day of storage (p = 0.001). It was also noted that mean G6PD activity for spotted blood samples were lower compared to those in EDTA tubes for all days (p = 0.001). Thus, EDTA blood samples stored at 2-8 °C appeared to have better stability in terms of their G6PD enzyme level as compared to dried blood samples on filter paper, giving a storage time of up to 3 days.
description: EXCLI Journal;Vol. 15, 2016