cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Issues on Generating Primordial Anisotropies at the End of Inflation
Creators: name: Emami, Razieh
name: Firouzjahi, Hassan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We revisit the idea of generating primordial anisotropies at the end of inflation in models of inflation with gauge fields. To be specific we consider the charged hybrid inflation model where the waterfall field is charged under a U(1) gauge field so the surface of end of inflation is controlled both by inflaton and the gauge fields. Using delta N formalism properly we find that the anisotropies generated at the end of inflation from the gauge field fluctuations are exponentially suppressed on cosmological scales. This is because the gauge field evolves exponentially during inflation while in order to generate appreciable anisotropies at the end of inflation the spectator gauge field has to be frozen and scale invariant. We argue that this is a generic feature, that is, one can not generate observable anisotropies at the end of inflation within an FRW background.
description: V3: new references added, JCAP published version
Proksee sessions with GIPSy2 comparisons
Creators: name: Rodrigues, Diego Lucas Neres
name: Sodrzeieski, Pedro
name: Benko-Iseppon, Ana Maria
name: Ramos, Rommel Thiago Jucá
name: Azevedo, Vasco Ariston de Carvalho
name: Soares, Siomar de Castro
name: Aburjaile, Flavia Figueira
Publisher: name: Zenodo
Year: 2023

description: Proksee sessions related to comparative analyses performed with GIPSy2.
Supporting material 1. Comparative analyses carried out with the chromosome of Acinetobacter baumannii strain AYE against the chromosome of A. baumannii strain SDF.
Supporting material 2. Comparative analysis carried out with the chromosome I of Burkholderia pseudomallei strain K96243 against the chromosome I of B. pseudomallei strain 668.
Supporting material 3. Comparative analysis carried out with the chromosome II of Burkholderia pseudomallei strain K96243 against the chromosome chromosome II of B. pseudomallei strain 668.
Supporting material 4. Comparative analyses carried out with the chromosome of Escherichia coli CFT073 against the chromosome of E. coli strain K-12 substrain MG1655.
Supporting material 5. Comparative analyses carried out with the chromosome of Mesorhizobium japonicum MAFF 303099 against the chromosome of Mesorhizobium sp. strain BNC1.
Supporting material 6. Comparative analyses carried out on the chromosome of Mesorhizobium japonicum MAFF 303099 against the chromosomes of Mesorhizobium sp. strain BNC1, M. loti strain TONO, M. loti strain R88b and M. japonicum strain R7Astar.
Quantum tomography in position and momentum space
Creators: name: Casanova, J.
name: Lopez, C. E.
name: Garcia-Ripoll, J. J.
name: Roos, C. F.
name: Solano, E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We introduce a method of quantum tomography for a continuous variable system in position and momentum space. We consider a single two-level probe interacting with a quantum harmonic oscillator by means of a class of Hamiltonians, linear in position and momentum variables, during a tunable time span. We study two cases: the reconstruction of the wavefunctions of pure states and the direct measurement of the density matrix of mixed states. We show that our method can be applied to several physical systems where high quantum control can be experimentally achieved.
description: 5 pages, 2 figures. To be published in EPJD
Finding the Strength: A Case Study of School District Leadership of Mental Health Promotion in One School District in British Columbia
Creators: name: Turner, Jennifer Louise
Publisher: name: Werklund School of Education
Year: 2022
Subjects: subject: educational leadership
subject: social network analysis
subject: qualitative network analysis
subject: mental health
subject: promotion
subject: multi-tiered systems of support
subject: Education--Administration
subject: Educational Psychology
subject: Education--Special

description: Mental illness is a public health emergency threatening our national youth's social, physical, and economic vitality (OECD, 2019). Despite K–12 public schools being an ideal setting to address mental health promotion and early intervention, literature indicates that system-level adoption and delivery of evidence-based practices across school settings are filled with challenges. This single-site case study explored the relationships and interdependencies that exist between district and school-based leaders in implementing mental health promotion and early intervention practices in one public school system in British Columbia. Social network analysis was used to identify the relationships and interdependencies that exist. Qualitative network analysis was used to create a rich description of the leadership practices within this system. Eleven findings were identified that are categorized into three key findings: 1) the school district was an interconnected, networked school district, 2) the leadership focused on student strengths and proactively engaged in intervention, and 3) the leaders across the district actioned social justice. The findings indicate that a school district and school leaders that develop strong internal connections across their leadership team also intentionally cultivate strong connections with community-based mental health services and support programs. Despite the strong interconnected, networked relationships, this study also found school-based leaders were reliant on specific leadership roles within the system, including the Assistant Superintendent, the Director of Instruction, the District Principal, and school-based counselors in their leadership of mental health promotion. Implications of these findings and recommendations for practice are included in this study.
Tracking and Analysis of Ecological Human Walking With Wearable Sensors
Creators: name: Carlisle, Rebecca Elizabeth
Publisher: name: Schulich School of Engineering
Year: 2022
Subjects: subject: Engineering--Biomedical

description: Gait studies performed in a laboratory setting might not fully represent real-life walking. Walking under constrained conditions, such as fixed speed or distance, can alter a person's gait. Humans often walk relatively short bouts that lack a steady speed, and longer bouts of varying movement vigor, meaning speed depends on the urgency of the task and who is performing it. Real world environments also contain diverse terrains that must be traversed. Thus, human walking in free-living conditions includes a wide range of gait parameters that may not be well-represented in laboratory studies. This project has three main parts. In the first, we quantify gait characteristics such as stride length, speed, and height, in young, healthy subjects (N = 11) in their everyday lives for seven days. Subjects take the majority of steps as part of short, variable walking bouts, and though they have a preferred speed, their actual stride speed is highly dependent on task. The second section expands the study to include a group of older adults (N = 14) for an investigation of how age affects gait. The older subjects have a similar preferred walking speed to the younger subjects, but also take more strides at a slower speed. For both groups, stride length increases with speed in a similar relationship to that studied in a lab. Finally, we show that speeds and durations of short walking bouts can be explained by a general objective for energy and time, defined as the total work or energy expended to reach destination, plus a subjective cost proportional to bout duration. This objective is both applied to a model and tested on humans (N = 10). Speed trajectories for short walking bouts resemble an inverted U, where shorter bouts only briefly peak in speed, in amounts increasing with bout distance. Speeds of any distance increase with an individual's subjective cost of time, which may differ between individuals, but in a systematic and scalable way. The Energy-Time cost for a task quantitatively predicts transient, steady, and vigor-related aspects of movement.
Subhaloes in Self-Interacting Galactic Dark Matter Haloes
Creators: name: Vogelsberger, Mark
name: Zavala, Jesus
name: Loeb, Abraham
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present N-body simulations of a new class of self-interacting dark matter models, which do not violate any astrophysical constraints due to a non-power-law velocity dependence of the transfer cross section which is motivated by a Yukawa-like new gauge boson interaction. Specifically, we focus on the formation of a Milky Way-like dark matter halo taken from the Aquarius project and re-simulate it for a couple of representative cases in the allowed parameter space of this new model. We find that for these cases, the main halo only develops a small core (~1 kpc) followed by a density profile identical to that of the standard cold dark matter scenario outside of that radius. Neither the subhalo mass function nor the radial number density of subhaloes are altered in these models but there is a significant change in the inner density structure of subhaloes resulting in the formation of a large density core. As a consequence, the inner circular velocity profiles of the most massive subhaloes differ significantly from the cold dark matter predictions and we demonstrate that they are compatible with the observational data of the brightest Milky Way dSphs in such a velocity-dependent self-interacting dark matter scenario. Specifically, and contrary to the cold dark matter case, there are no subhaloes that are more concentrated than what is inferred from the kinematics of the Milky Way dSphs. We conclude that these models offer an interesting alternative to the cold dark matter model that can reduce the recently reported tension between the brightest Milky Way satellites and the dense subhaloes found in cold dark matter simulations.
description: 14 pages, 9 figures, MNRAS accepted
Design & Performance Evaluation of a Bandwidth Shaper with Encrypted P2P Detection
Creators: name: ธงชัย เจือจันทร์
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2010
Subjects: peer-to-peer traffic
protocol
evaluation

description: Journal of Information Science and Technology, 1, 2, 32-38
Studying the Interaction of RACK-1 and GLD-1 in the Germline of Caenorhabditis elegans
Creators: name: Sangari, Sadaf
Publisher: name: Science
Year: 2022
Subjects: subject: GLD-1
subject: RACK-1
subject: Caenorhabditis elegans
subject: Germline Stem Cells
subject: Immunoprecipitation
subject: CRISPR
subject: Education--Sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Biology--Molecular
subject: Biochemistry

description: Stem cells are undifferentiated cells that can proliferate to produce more stem cells or differentiate to produce specialized cells. Two gonad arms are present within the germline of the hermaphrodite C. elegans, where proliferating germline stem cells (GSCs) are located at the distal end while meiotic cells occur more proximally, eventually differentiating as gametes. The balance between proliferation and differentiation allows this spatial patterning to be maintained in the germline. Our lab has been studying the influence of highly conserved scaffold protein RACK-1 (Receptor for Activated C Kinase 1) and translational repressor GLD-1 (Defective in Germline Development 1) on the proliferation differentiation decision of GSCs. RACK-1 is involved in ribosome assembly and the miRISC pathway. Meanwhile, GLD-1 functions in germline stem cell entry and progression through meiosis as well as oogenesis and sex determination. Previous work had shown that an absence of rack-1 results in lower GLD-1 levels as well as GLD-1 mis-localization to P granules. Furthermore, an absence of rack-1 resulted in an over-proliferation phenotype in a glp-1(ar202gf) background. As a result, a model was proposed where a potential interaction between RACK-1 and GLD-1 was predicted. In this thesis, I investigated the possible physical interaction between RACK-1 and GLD-1. RACK-1 strains were tagged using CRISPR technology. These strains were shown to behave similarly to a wildtype organism through immunostaining and brood size assay experiments. As a result, the strains were used as reagents for co-immunoprecipitation experiments to detect an interaction between GLD-1 and RACK-1. The same CRISPR tagged strains were used to show that RACK-1 was expressed in the cytoplasm and on cellular membranes in the germline. Several variations of co-immunoprecipitation experiments were performed, where an interaction between RACK-1 and GLD-1 was detected when GLD-1 was immunoprecipitated. The pulldown of RACK-1 with GLD-1 indicated a physical interaction within the cytoplasm that may be direct or indirect. This research gave us insight into the potential influence of this interaction on the proliferation differentiation decision of GSCs. RACK-1 may help GLD-1 by stabilizing it, in turn allowing it to function normally as a translational repressor, which allows for an organized germline.
Activity-dependent neuronal model on complex networks
Creators: name: de Arcangelis, Lucilla
name: Herrmann, Hans J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Neuronal avalanches are a novel mode of activity in neuronal networks, experimentally found in vitro and in vivo, and exhibit a robust critical behaviour: These avalanches are characterized by a power law distribution for the size and duration, features found in other problems in the context of the physics of complex systems. We present a recent model inspired in self-organized criticality, which consists of an electrical network with threshold firing, refractory period and activity-dependent synaptic plasticity. The model reproduces the critical behaviour of the distribution of avalanche sizes and durations measured experimentally. Moreover, the power spectra of the electrical signal reproduce very robustly the power law behaviour found in human electroencephalogram (EEG) spectra. We implement this model on a variety of complex networks, i.e. regular, small-world and scale-free and verify the robustness of the critical behaviour.
description: 9 pages, 8 figures
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) : a rhabdomyosarcoma therapy target and mitochondrial DNA repair enzyme
Creators: name: Chowdhury, Md. Miraj Kobad
Publisher: name: University of British Columbia
Year: 2012

description: Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs blocked 3´ DNA termini to enable DNA repair. The H493R mutation in TDP1, which disrupts the active site of the enzyme and leads to formation of long-lived TDP1-DNA adducts, causes the progressive neurodegenerative disease spinocerebellar ataxia with axonal neuropathy 1 (SCAN1). Loss of function of TDP1 results in increased sensitivity towards several genotoxic agents including camptothecin analogues, bleomycin and ionizing radiation in vitro and in vivo. In this study, the rationale for using TDP1 as a therapeutic anticancer target and the role of functional loss of TDP1 in neurodegeneration were investigated. Using immunohistochemical staining, immunofluorescence microscopy, sub-cellular fractionation, immunoblotting, TUNEL assays, and PCR, TDP1 expression and the consequences of its loss were studied in different human tissues, tumor tissues, rhabdomyosarcoma cell lines and murine retina. Twenty-four out of twenty six different human tumors were TDP1 positive. Rhabdomyosarcoma cell lines expressing TDP1 in the mitochondria showed higher resistance to camptothecin compared to those not expressing TDP1 in the mitochondria. Loss of TDP1 reduced growth and increased camptothecin sensitivity in all rhabdomyosarcoma cell lines. To better understand the role of TDP1 in the mitochondria, I identified a tissue in mouse in which murine TDP1 is exclusively expressed in the mitochondria, photoreceptors, and found that Tdp1⁻/⁻ mice had degenerating rod and cone cells from postnatal day 11 associated with an increased level of oxidative mitochondrial DNA damage and apoptosis. These observations indicated that murine TDP1 plays an important role in mitochondria by repairing mitochondrial DNA and that murine TDP1 in mitochondria protects photoreceptors from degeneration. They also suggest that mitochondrial TDP1 renders cancer cells resistant to some chemotherapy and radiotherapy regimes, and that mitochondrial TDP1 is a potential anticancer target.
PT Symmetric, Hermitian and P-Self-Adjoint Operators Related to Potentials in PT Quantum Mechanics
Creators: name: Azizov, Tomas
name: Trunk, Carsten
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 34L05, 47B50

description: In the recent years a generalization $H=p^2 +x^2(ix)^ε$ of the harmonic oscillator using a complex deformation was investigated, where ε is a real parameter. Here, we will consider the most simple case: εeven and x real. We will give a complete characterization of three different classes of operators associated with the differential expression H: The class of all self-adjoint (Hermitian) operators, the class of all PT symmetric operators and the class of all P-self-adjoint operators. Surprisingly, some of the PT symmetric operators associated to this expression have no resolvent set.
Statistical Physics approach to dendritic computation: The excitable-wave mean-field approximation
Creators: name: Gollo, Leonardo L.
name: Kinouchi, Osame
name: Copelli, Mauro
Publisher: name: arXiv
Year: 2011
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Cellular Automata and Lattice Gases (nlin.CG)
subject: Biological Physics (physics.bio-ph)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: We analytically study the input-output properties of a neuron whose active dendritic tree, modeled as a Cayley tree of excitable elements, is subjected to Poisson stimulus. Both single-site and two-site mean-field approximations incorrectly predict a non-equilibrium phase transition which is not allowed in the model. We propose an excitable-wave mean-field approximation which shows good agreement with previously published simulation results [Gollo et al., PLoS Comput. Biol. 5(6) e1000402 (2009)] and accounts for finite-size effects. We also discuss the relevance of our results to experiments in neuroscience, emphasizing the role of active dendrites in the enhancement of dynamic range and in gain control modulation.
description: 30 pages, 8 figures
AUTOCUIDADO EN PACIENTES CON INSUFICIENCIA RENAL CRÓNICA EN TRATAMIENTO DE HEMODIÁLISIS
Creators: name: Quiñonez Cabeza, Pedro
name: Ochoa Anastacio, María Elena
name: Genovesi Anguizaca, Gabriela
name: Cusquillo  Guamán, Lenin
Publisher: name: Zenodo
Year: 2023

description: La Insuficiencia Renal Crónica (IRC), es uno de los retos más significativos de la salud pública, en los países latinoamericanos que aún no logran establecer programas de salud eficientes, debido al rápido aumento de su prevalencia, elevados costos en el tratamiento y alta frecuencia de complicaciones. De ahí que la terapia de sustitución renal no es sólo prolonga la vida, sino que también restaurar la calidad de ésta, para lograrlo es fundamental que los pacientes se adhieran a su tratamiento. El propósito de este estudio es determinar el nivel de autocuidado de los pacientes con Insuficiencia Renal Crónica sometidos a Hemodiálisis en una unidad de Hemodiálisis. Material y método: El estudio es de enfoque cuantitativo, de tipo descriptivo y de corte transversal. La población estuvo conformada por 60 pacientes adultos con Insuficiencia Renal Crónica sometidos a Hemodiálisis (HD) en una unidad de diálisis. La técnica que se utilizó fue la encuesta y el instrumento un cuestionario estructurado, elaborado y validado por los autores, constituida por 22 preguntas. El análisis se realizó con el programa estadístico SPSS para Windows, versión 20, calculando las frecuencias absolutas, relativas y la frecuencia promedio.
Magnetic field-induced electric quadrupole moment in the ground state of the relativistic hydrogen-like atom: Application of the Sturmian expansion of the generalized Dirac-Coulomb Green function
Creators: name: Szmytkowski, Radosław
name: Stefańska, Patrycja
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We consider a Dirac one-electron atom placed in a weak, static, uniform magnetic field. We show that, to the first order in the strength $B$ of the perturbing field, the only electric multipole moment induced by the field in the ground state of the atom is the quadrupole one. Using the Sturmian expansion of the generalized Dirac-Coulomb Green function [R. Szmytkowski, J. Phys. B 30 (1997) 825; erratum 30 (1997) 2747], we derive a closed-form expression for the induced electric quadrupole moment. The result contains the generalized hypergeometric function $_{3}F_{2}$ of the unit argument. Earlier calculations by other authors, based on the non-relativistic model of the atom, predicted in the low-field region the quadratic dependence of the induced electric quadrupole moment on $B$.
description: LaTeX2e, 9 pages
Social Support in Group Exercise Programs for Adults Living with and Beyond Cancer
Creators: name: Craig, Bobbie-Ann Pauline
Publisher: name: Kinesiology
Year: 2022
Subjects: subject: Education--Health
subject: Education--Social Sciences
subject: Oncology

description: Physical activity is an effective intervention for alleviating many physical, emotional, and social stressors faced in survivorship, and for improving the quality of life of adults living with cancer. Social support is positively associated with physical activity and is important for helping adults living with cancer cope with the challenges of cancer and issues in survivorship. Group physical activity programs can provide opportunities for social support from other individuals living with cancer, as well as fitness professionals leading the program. The purpose of this thesis was to better understand what types of social support and supportive behaviours are perceived as supportive and are associated with greater physical activity and quality of life in group exercise oncology programs. The first study cross-sectionally examined the associations between 16 social support predictors and 5 quality of life outcomes, 5 self-report physical activity outcomes, and objectively measured average daily step count. Hypotheses were tested using multiple regression. Self-report moderate-to-vigorous physical activity was positively predicted by reassurance of worth support, general and social well-being were negatively predicted by thwarting relatedness, and physical well-being was positively predicted by social network within group exercise oncology programs. The second study examined current practices for training fitness professionals to provide and facilitate social support, experiences people living with cancer have of social support, and supportive behaviours and barriers for providing and obtaining support in online group exercise oncology programs. Training materials were reviewed, observations of fitness professional training and online exercise classes (N=10) were conducted, and adults living with cancer (N=19), and fitness professionals (N=15) were interviewed. Data analysis was guided by interpretive description methodology (Thorne, 2016), and interpreted in light of Feeney and Collins’ (2015) social support theory. Three themes were identified: creating a welcoming atmosphere, helping improve exercise ability and reach goals, and learning to provide and facilitate support online. Together these studies provide insight into specific behaviours adults living with cancer find supportive, and social barriers in the group exercise oncology context to inform fitness professional training and program development to enhance and promote a socially supportive environment.
Bridging the Gap - Exploring the Role of Cortisol on The Effects of Prenatal Depression on Child Neurocognition
Creators: name: Cattani, Danielle
Publisher: name: Cumming School of Medicine
Year: 2022
Subjects: subject: Prenatal depression
subject: Executive function
subject: Cortisol
subject: fetal development
subject: fetal programming
subject: DOHaD
subject: Cognition
subject: Child health
subject: Prenatal mental health
subject: Education--Early Childhood
subject: Education--Health
subject: Education--Sciences
subject: Neuroscience
subject: Human Development
subject: Mental Health
subject: Psychology--Cognitive
subject: Psychology--Developmental
subject: Psychobiology

description: Prenatal depression is a potentially debilitating experience that can affect both birthing parent and child. The current study investigates the role of cortisol, a hormone well-known for its involvement in the stress response, in the association between prenatal depression and child neurocognitive outcomes. Specifically, we assessed child executive function and cortical thickness in the right frontal and prefrontal cortices. Pregnant participants completed the Edinburgh Postnatal Depression Scale (EPDS) to assess prenatal depression, and we examined prenatal cortisol using salivary cortisol samples. Children completed six executive function tasks spanning the three domains of executive functioning and underwent magnetic resonance imaging to assess their cortical thickness. Our results indicate that prenatal depression during pregnancy, particularly early pregnancy, has the potential to adversely impact mental flexibility in children ages 3 – 4 years. Furthermore, an elevated prenatal cortisol awakening response (CAR) was related to timing-specific and region-specific cortical thinning in the right frontal cortex of children ages 3 – 7 years. Lastly, increased CAR in the third trimester was associated with better mental flexibility outcomes. Prenatal cortisol did not mediate the relationship between prenatal depression and child cortical thickness or executive function outcomes in our sample. Future research directions are discussed. Our study emphasizes the importance of caring for prenatal mental health in improving outcomes for child neurocognition.
Towards understanding multiscale articular cartilage mechanics
Creators: name: Sibole, Scott
Publisher: name: Schulich School of Engineering
Year: 2022
Subjects: subject: Engineering--Biomedical

description: The mechanical environment of the chondrocytes, the sole cell type in articular cartilage, is of high importance to developing and maintaining a healthy tissue state. Mechanical cues play a major role in the regulation of many cellular functions. The dominant mechanics experienced by chondrocytes are translated from physics occurring at the scale of the body (1 m) to the cellular scale (1×10−5 m). This large breadth of scale leads to many challenges when investigating chondrocyte mechanics both mathematically and experimentally. A popular mathematical approach is to solve boundary value problems defined by the governing equations from classical mechanics at different spatial scales such as the body, joint, tissue, and cellular with some defined coupling between them. Such multiscale modelling offers great investigative scope, but also requires many technical considerations that necessitate validation. Experimentation can offer a means for validation and additional investigation. A popular experimental approach employs laser scanning microscopy coupled with mechanical testing systems capable of acquiring 3-D images of tissue subjected to controlled mechanical conditions. By comparing tissue volumes in different mechanical states, micro-scale deformation can be calculated. This work focused on the extension of the current analysis toolkit of such multiscale experimental data. Software was developed for improved segmentation of cellular scale geometries. A novel experimental method and analysis software were developed that utilized deformable image registration to quantify tissue deformation. A specimen staining and imaging protocol for morphometrics of the pericellular matrix was developed along with data analysis software. These morphometrics revealed a distinct directed pericellular matrix asymmetry, which was investigated through multiscale finite element modelling. Simulations indicated that such directed asymmetry may provide mechanical protections to the cellular membrane during fast-loading conditions. Finally, the image acquisition rate of laser scanning microscopy has historically restricted it to measuring steady-state mechanics. To circumvent this limitation, the rapid acquisition rate of resonance scanning was employed to measure transient cellular-scale mechanics. A software package to quantify tissue and cellular deformation from resonance-scanned images was developed. Resonance scanning and the subsequent analysis exhibited robust and accurate performance indicating its usefulness as a tool to study such dynamics.
Uncertainty Among Youth with Chronic Pain, their Parents, and Clinicians
Creators: name: Neville, Alexandra
Publisher: name: Arts
Year: 2022
Subjects: subject: chronic pain
subject: pediatric
subject: youth
subject: children
subject: adolescents
subject: parents
subject: diagnostic uncertainty
subject: intolerance of uncertainty
subject: fear avoidance
subject: Psychology--Clinical

description: Objective: Uncertainty is inherent to the experience of chronic primary pain (CPP). Diagnostic uncertainty (DU) has been alluded to in the pediatric chronic pain literature; however, the prevalence, facets, impacts, and drivers of this phenomenon have yet to be explored. The objectives of this dissertation were to explore DU among youth with CPP, their parents, and clinicians, and how it is influenced by the clinical encounter. As well, youth and parent intolerance of uncertainty were investigated as potential risk factors in the Interpersonal Fear Avoidance Model of Pain. Methods: Data included samples of youth with CPP seeking treatment in tertiary level care settings, their parents, and clinicians who treat youth with CPP. These samples spanned three geographical locations, including Canada, the United Kingdom, and the United States. Uncertainty was investigated using a multi-method approach. DU was explored qualitatively from the perspectives of youth, parents, and clinicians, as well as quantitatively among youth and parents. Intolerance of uncertainty was investigated quantitatively using self-report measures. Finally, interpretative phenomenological analysis was used to explore components of the clinical encounter that influence youth’s and parents’ experiences of DU. Results: DU is characterized by fear that something more serious is causing youth’s pain, which fuels a search for alternative diagnoses. Approximately one-third of youth with CPP and their parents experience DU, which is linked to poorer youth pain, pain-related constructs, and health-related quality of life. Clinicians also experience DU treating youth with CPP. Components of the clinical encounter, including pain explanations, validation, and messages of uncertainty, influence youth’s and parents’ experiences of DU, which has implications for youth’s engagement in treatment. Results also suggest that parent and youth intolerance of uncertainty contribute to increases in youth pain interference over time through increased pain catastrophizing, parent protectiveness, and youth fear of pain. Conclusions: This dissertation characterized the multifaceted nature of DU among youth with CPP, their parents, and clinicians, and demonstrated that it is common and often debilitating. Further, parent and youth intolerance of uncertainty play important roles as risk factors in the maintenance of pediatric chronic pain over time.
Model dependence of the bremsstrahlung effects from the superluminal neutrino at OPERA
Creators: name: Bezrukov, Fedor
name: Lee, Hyun Min
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We revisit the bremsstrahlung process of a superluminal neutrino motivated by OPERA results. From a careful analysis of the plane wave solutions of the superluminal neutrino, we find that the squared matrix elements contain additional terms from Lorentz violation due to the modified spin sum for the neutrino. We point out that the coefficients of the decay rate and the energy loss rate significantly depend on the details of the model, although the results are parametrically similar to the ones obtained by Cohen and Glashow [1]. We illustrate this from the modified neutral current interaction of neutrino with Lorentz violation of the same order as in the modified dispersion relation.
description: 10 pages, no figures, version to appear as a Rapid Communication in Phys. Rev. D
Factors associated with improved walking in older people during hospital rehabilitation: secondary analysis of a randomized controlled trial
Creators: name: Said, Catherine M
name: McGinley, Jennifer L
name: Szoeke, Cassandra
name: Workman, Barbara
name: Hill, Keith D
name: Wittwer, Joanne
name: Woodward, Michael
name: Liew, Danny
name: Churilov, Leonid
name: Bernhardt, Julie
name: Morris, Meg
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4203
subject: Health services and systems

description: Abstract Background Older people are often admitted for rehabilitation to improve walking, yet not everyone improves. The aim of this study was to determine key factors associated with a positive response to hospital-based rehabilitation in older people. Methods This was a secondary data analysis from a multisite randomized controlled trial. Older people (n= 198, median age 80.9 years, IQR 76.6- 87.2) who were admitted to geriatric rehabilitation wards with a goal to improve walking were recruited. Participants were randomized to receive additional daily physical therapy focused on mobility (n = 99), or additional social activities (n = 99). Self-selected gait speed was measured on admission and discharge. Four participants withdrew. People who changed gait speed ≥0.1 m/s were classified as ‘responders’ (n = 130); those that changed <0.1m/s were classified as ‘non-responders’ (n = 64). Multivariable logistic regression explored the association of six pre-selected participant factors (age, baseline ambulation status, frailty, co-morbidities, cognition, depression) and two therapy factors (daily supervised upright activity time, rehabilitation days) and response. Results Responding to rehabilitation was associated with the number of days in rehabilitation (OR 1.04; 95% CI 1.00 to 1.08; p = .039) and higher Mini Mental State Examination scores (OR 1.07, 95% CI 1.00 – 1.14; p = .048). No other factors were found to have association with responding to rehabilitation. Conclusion In older people with complex health problems or multi-morbidities, better cognition and a longer stay in rehabilitation were associated with a positive improvement in walking speed. Further research to explore who best responds to hospital-based rehabilitation and what interventions improve rehabilitation outcomes is warranted. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12613000884707; ClinicalTrials.gov Identifier NCT01910740.
Biotic response to riparian disturbance in head-water streams in British Columbia
Creators: name: Goodwin, Adam
Publisher: name: University of British Columbia
Year: 2012

description: Five forest disturbance regimes (wildfire, mountain pine beetle (MPB), commercial harvest, and two sets of references) were investigated to determine transitive effects on aquatic ecosystems in fifteen headwater streams in the southern interior of British Columbia. The particular focus for this study was aquatic macro-invertebrates and their trophic resources (forest litter, periphyton, and particulate organic matter). At each site, sampling occurred three times over the summer and fall of 2009, across a one-hundred meter reach. Disturbances resulted in clear alterations of canopy coverage and litter loading. The two canopy consuming disturbances (fire and harvesting) showed marked decreases in their proportional canopy coverage. Litter loading in MPB was significantly greater, while fire streams’ litter loading was directly related to canopy coverage, and significantly less than reference sites. Periphyton mean growth was unrelated to disturbance; however inter-stream variance was reduced in the burned systems and increased in the MPB systems. Macro-invertebrate measurements were not different across disturbances, however, abundances and biomass did exhibit different temporal interactions with the Montane Spruce disturbances. Abundances of invertebrate functional feeding groups were unrelated to their food resource, and did not differ across disturbance type. Invertebrate diversity measurements were also similar across disturbance regime. While aquatic ecosystems were generally robust in response to riparian disturbance events in this study, we were able to uncover slight differences across disturbance regimes. The temporal and spatial findings in this paper are of particular importance as they illustrate differences between MPB and salvage logging effects.
Factors associated with improved walking in older people during hospital rehabilitation: secondary analysis of a randomized controlled trial
Creators: name: Said, Catherine M
name: McGinley, Jennifer L
name: Szoeke, Cassandra
name: Workman, Barbara
name: Hill, Keith D
name: Wittwer, Joanne E
name: Woodward, Michael
name: Liew, Danny
name: Churilov, Leonid
name: Bernhardt, Julie
name: Morris, Meg
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Abstract Background Older people are often admitted for rehabilitation to improve walking, yet not everyone improves. The aim of this study was to determine key factors associated with a positive response to hospital-based rehabilitation in older people. Methods This was a secondary data analysis from a multisite randomized controlled trial. Older people (n= 198, median age 80.9 years, IQR 76.6- 87.2) who were admitted to geriatric rehabilitation wards with a goal to improve walking were recruited. Participants were randomized to receive additional daily physical therapy focused on mobility (n = 99), or additional social activities (n = 99). Self-selected gait speed was measured on admission and discharge. Four participants withdrew. People who changed gait speed ≥0.1 m/s were classified as ‘responders’ (n = 130); those that changed <0.1m/s were classified as ‘non-responders’ (n = 64). Multivariable logistic regression explored the association of six pre-selected participant factors (age, baseline ambulation status, frailty, co-morbidities, cognition, depression) and two therapy factors (daily supervised upright activity time, rehabilitation days) and response. Results Responding to rehabilitation was associated with the number of days in rehabilitation (OR 1.04; 95% CI 1.00 to 1.08; p = .039) and higher Mini Mental State Examination scores (OR 1.07, 95% CI 1.00 – 1.14; p = .048). No other factors were found to have association with responding to rehabilitation. Conclusion In older people with complex health problems or multi-morbidities, better cognition and a longer stay in rehabilitation were associated with a positive improvement in walking speed. Further research to explore who best responds to hospital-based rehabilitation and what interventions improve rehabilitation outcomes is warranted. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12613000884707; ClinicalTrials.gov Identifier NCT01910740.
ADHD Does not Define me: Parent-Child Reported Strengths in Children with ADHD
Creators: name: Miller, Courtney
Publisher: name: Werklund School of Education
Year: 2022
Subjects: subject: ADHD
subject: Strengths
subject: Self-Perception
subject: Parent-Perception
subject: Education
subject: Education--Early Childhood
subject: Educational Psychology
subject: Education--Social Sciences
subject: Psychology
subject: FOS: Psychology
subject: Psychology--Developmental

description: A strength-based approach to childhood attention-deficit/hyperactivity disorder (ADHD) research highlights children’s positive attributes that can support their areas of difficulty (Climie et al., 2015). However, research on perceptions of a child’s positive attributes is understudied. Specifically, there is little research that examines strength-based perceptions of children with ADHD, and only one known article addresses parent perceptions of their children with ADHD (Mastoras et al., 2018). As such, this study analyzed parent and child reported strengths in children with ADHD. Parent and child reported strengths were measured using the Behavioral and Emotional Rating Scale – 2nd edition, Parent Form and Child Form (BERS-2; Epstein, 2004). Results indicated that parents and children perceived strengths in the interpersonal, intrapersonal, and affective domains to be similar, falling in the Average range. However, children indicated their family involvement and school functioning fell within the Average range, whereas parents rated these domains in the Below Average range. Positive parental perspectives of their children may promote positive parent-child interactions and serve as an overall protective factor for children (Sabapathy et al., 2017) with ADHD. Additionally, parents and children categorized ADHD descriptions and attitudes towards ADHD, similarly. Domains which parents and children see as strengths should be utilized to support areas of weakness. Strength-based research for children with ADHD and positive interventions utilizing strengths, may benefit families with ADHD, as well as classroom teachers and school psychologists.
D-JRP-PARADISE-WP4.3 Report on the probes designed to targets developed in WP3 for C. parvum and G. duodenalis
Creators: name: Lalle Marco
name: Caccio Simone M
name: Troell Karin
name: Opsteegh Marieke
Publisher: name: Zenodo
Year: 2021
Subjects: post-DNA enrichment, single-stranded byotinilated DNA probes, magnetic capture

description: This is a deliverable from WP4 of the OHEJP project PARADISE, and deals with the development of protocols for post-DNA enrichment to concentrate parasite DNA based on hybridization of target-specific biotinylated probes.
OSVH Co-Design Toolbox for Village Hosts
Creators: name: Menichinelli, Massimo
name: De Spirito, Denise
Publisher: name: Zenodo
Year: 2023
Subjects: co-design
toolbox
social innovation

description: OSVH Co-Design Toolbox for Village Hosts
 Designed by Massimo Menichinelli and Denise de Spirito
 v1.0
 03/2023 from the Open School for Village Hosts
 Project ID 2021-1-IT01-KA220-VET-000034855
 https://www.villagehosts.eu/ Based on: Menichinelli, Massimo, Priscilla Ferronato, Diana Pamela Villa Alvarez, and Marion Real. “SISCODE Toolbox for Co-Creation Journeys.” SISCODE, 2019. https://siscodeproject.eu/wp-content/uploads/2019/09/toolkit-27092019-1.pdf.
Characterising moose habitat, abundance and ecosystem variability using satellite-derived indicators
Creators: name: Michaud, Jean-Simon
Publisher: name: University of British Columbia
Year: 2012

description: Natural variability and disturbance events drive spatial and temporal variation in ecosystem processes and play key roles in ecosystem variety and the maintenance of species diversity. As a result, an improved understanding of the links between natural environmental variability and species diversity is needed to guide prioritisation of conservation and management actions. Ontario, the second largest province in Canada, covering approximately 1 million km², is environmentally diverse and is subject to a large amount of natural and anthropogenic disturbances. Remote sensing is uniquely capable of monitoring dynamic ecosystems over large areas in a repeatable and cost effective manner and has been shown to provide considerable benefit to assess species distribution and biodiversity. This thesis (1) examines an approach for detecting natural variability and disturbances of vegetation productivity from a remote sensing time-series and (2) demonstrates the use of satellite-derived indicators for the characterisation of moose habitat across Ontario. First, an approach was developed to assess temporal trends in vegetation productivity which utilised a Theil-Sen’s non-parametric statistical trend test over a 6-year period (2003-2008) of ten-day composites of Medium Resolution Imaging Spectroradiometer (MERIS) fraction of Photosynthetically Active Radiation (fPAR). Results indicated that this novel remote sensing approach can be used to characterise trends in landscape productivity patterns over large areas and can aid in provincial and national monitoring activities. Second, the research investigated the application of remotely sensed indicators such as vegetation productivity, land cover, topography, snow cover and natural and anthropogenic disturbances to predict moose occurrence and abundance. Results indicated that remotely sensed indicators were significantly correlated to moose habitat suitability with moose distribution being more accurately estimated than moose abundance. In addition to providing insights into the relative importance of the predictor covariates for moose occurrence and abundance, this study creates opportunities for further development of spatial models that closely examine the occurrence/abundance-habitat relationships which are highly valuable for habitat management decisions.