cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Modelling spatiotemporal trends in the frequency of genetic mutations conferring insecticide target-site resistance in African mosquito malaria vector species
Creators: name: Hancock, Penelope A.
name: Lynd, Amy
name: Wiebe, Antoinette
name: Devine, Maria
name: Essandoh, John
name: Wat’senga, Francis
name: Manzambi, Emile Z.
name: Agossa, Fiacre
name: Donnelly, Martin J.
name: Weetman, David
name: Moyes, Catherine L.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1: Additional results and information to support this manuscript, including: Figure S1. Results of 10-fold out-of-sample posterior validation for the spatiotemporal model ensemble. Figures S2 & S3. Sampling locations of the observed frequencies of the Vgsc-995F and Vgsc-995S markers in Africa that were included in our modelling analysis. Figures S4 & S5. The number of samples of the frequencies of the Vgsc-995F and Vgsc-995S markers included in our data set for each country. Figure S6. The total number of Vgsc allele frequency observations that were used to inform the spatiotemporal model ensemble by each year and each vector species. Figure S7. The abundance of An. arabiensis relative to the combined abundance of An. gambiae and An. coluzzii in the nine mapped countries. Figures S8, S9, S10 & S11. Associations between predicted frequencies of Vgsc mutations across species. Figures S12, S13 & S14. The ITN coverage across the nine mapped countries in years 2005, 2011 and 2017. Figure S15. The predicted L1014F frequency in the An. gambiae complex derived from combining species-specific frequencies (eq 1) vs observed frequencies. Table S1. The root mean square error (RMSE) and the mean absolute error (MAE) across the out-of-sample predictions of all Vgsc allele frequency observations, obtained using 10-fold cross validation. Table S2. Countries that were included in (i) each type of mapping analysis, and (ii) in the analysis of relationships between deltamethrin resistance phenotype and Vgsc mutation frequencies. Table S3. Descriptions of each potential explanatory variable used in the ensemble model.
ZFP423, a transcription factor implicated in Joubert Syndrome and Cerebellar Vermis Hypoplasia, orchestrates the pace and mode of cerebellar neurogenesis
Creators: name: Croci, Laura
name: Bosone, Camilla
name: Bergamini, Giorgio
name: Podini, Paola
name: Quattrini, Angelo
name: Badaloni, Aurora
name: Pagani, Antonella
name: Politi, Letterio
name: Sarna, Justyna
name: Hawkes, Richard
name: Warming, Søren
name: Cremona, Ottavio
name: Consalez, G. Giacomo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Cerebellar organogenesis; cerebellar neurogenesis; primary cilium; ciliopathies.

description: Neurogenesis is a tightly regulated process, both in the embryonic and in the adult brain. Its success depends on the ability of a germinative epithelium to establish the appropriate balance between maintaining an undifferentiated progenitor pool and giving birth to sequential generations of neurons and glia. The Zfp423 gene encodes a 30 Zn-finger transcription factor (TF) which interacts with the SMAD1- SMAD4 complex (BMP signaling), Notch intracellular domain, retinoic acid receptors and Collier/Olf-1/EBF TFs. This gene has been previosly implicated in cerebellar development. Mutations in the human ortholog ZNF423 have been identified in patients carrying cerebellar vermis hypoplasia (CVH) or Joubert Syndrome (JS), and/ or exhibiting other signs of ciliopathy outside the central nervous system. We have been analyzing two mouse mutant lines carrying allelic in-frame deletions of Zfp423. One of them lacks Zn-finger domains 9-20 (Δ9-20), implicated in BMP and Notch signal transduction, while the other lacks a C-terminal domain (Δ28-30). Both mutants exhibit cerebellar malformations and severe ataxia. However, our results indicate that the two protein domains play sharply distinct roles in the context of cerebellar neurogenesis. In Zfp423Δ9-20/Δ9-20 mutants, GABAergic Purkinje cell (PC) neurogenesis is impaired and the PC progenitor pool in the ventricular zone is precociously depleted. Conversely, Zfp423Δ28-30/Δ28-30 mutants display a selective impairment in the development of glutamatergic cerebellar neurons.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Classicalization of Nonclassical Quantum States in Loss and Noise -- Some No-Go Theorems
Creators: name: Yuen, Horace P.
name: Nair, Ranjith
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The general problem of performance advantage obtainable by the use of nonclassical transmitted states over classical ones is considered. Attention is focused on the situation where system loss is significant and additive Gaussian noise may be present at the receiver. Under the assumption that the total received state is classical, rigorous output density operator representations and their trace distance bounds are developed for classical and nonclassical transmitted states. For applications with high loss in all modes, a practical No-Go theorem is enunciated that rules out the possibility of significant advantage of nonclassical over classical states. The recent work on quantum illumination is discussed as an example of our no-go approach.
description: Accepted to PRA; revised version
A study of the organic matter in sea water
Creators: name: Papafingos, Pandelis Nicolas
Publisher: name: University of British Columbia
Year: 2012

description: During the present work, we studied the organic matter in British Columbia sea waters. A carbohydrate substance was found with the characteristics of a uronic acid. The approach was made in two ways: (1) By applying spectrophotometrically the phenol sulfuric acid test for the determination of sugars and related substances, as described by M. Dubois, K.A. Gilles, J.K. Hamilton, P.A. Rebers and F. Smith (11) directly to sea water without previous separation of sea water constituents, and (2), by applying this same phenol sulfuric acid test with previous separation of the constituents found in sea water, by making use of deionization, charcoal column separations, adsorption, solvent extraction and paper chromatography. In the case of the spectrophotometry study of the phenol sulfuric acid test applied directly to sea water, the possible interference of a certain number of constituents was also studied. Furthermore, solvent extraction and paper chromatography showed the presence of 3 waxes in sea water. One of those had the same melting point, 11 C, as a wax reported by Dr. Swain from Bute Inlet, where it is found in quantity. We also found two other waxes, one melting at 61 C, and the other, because of its minute quantity, was obtainable only in the chromatogram and no melting point value was possible.
title: ÐÐ½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ñ ÐºÐ°Ðº ÑÐ»ÐµÐ¼ÐµÐ½Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐ¾Ð²Ð°ÑÐ½ÑÐ¼Ð¸ Ð·Ð°Ð¿Ð°ÑÐ°Ð¼Ð¸
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: Ð¤Ð¸ÑÐ¸ÑÐ¾Ð²Ð°, ÐÐ°ÑÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ñ
ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ Ð·Ð°Ð¿Ð°ÑÐ°Ð¼Ð¸
ÑÐ¾Ð²Ð°ÑÐ¾Ð¾Ð±Ð¾ÑÐ¾Ñ
inventory
inventory management
commodity turnover

description: Ð¦ÐµÐ»Ñ ÑÐ°Ð±Ð¾ÑÑ Ð·Ð°ÐºÐ»ÑÑÐ°ÐµÑÑÑ Ð² Ð¾Ð±ÑÑÑÐ½ÐµÐ½Ð¸Ð¸ Ð»Ð¾Ð³Ð¸ÐºÐ¸ Ð¸ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð¾Ð² Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ ÑÐµÑÑÑÑÐ¾Ð² Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, ÑÐ¾, Ð¸ ÐºÐ°ÐºÐ¸Ð¼ Ð¾Ð±ÑÐ°Ð·Ð¾Ð¼ ÐºÐ°ÑÐµÑÑÐ²Ð¾ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð²Ð»Ð¸ÑÐµÑ Ð½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ. ÐÐ¸Ð¿Ð»Ð¾Ð¼Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½Ñ - Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ñ ÐºÐ°Ðº ÑÐ»ÐµÐ¼ÐµÐ½Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐ¾Ð²Ð°ÑÐ½ÑÐ¼Ð¸ Ð·Ð°Ð¿Ð°ÑÐ°Ð¼Ð¸. Ð Ð¢ÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸ ÑÐ°Ð±Ð¾ÑÑ Ð´Ð°Ð½Ð¾ Ð¿Ð¾Ð´ÑÐ¾Ð±Ð½Ð¾Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð¾Ð² Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐ¾ÑÐ¼ÑÐ»Ñ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð¿Ð¾ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐµÐ¼Ðµ. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð´Ð°Ð½Ð½ÑÑ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ ÐÐÐ Â«Ð¢Ð ÐÑÐ¸ÑÑÐ°Ð»Ð»Â». ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð² Ð±ÑÑÐ³Ð°Ð»ÑÐµÑÑÐºÐ¾Ð¼ ÑÑÐµÑÐµ. ÐÑÑÐ°Ð¶ÐµÐ½Ð° Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ°Ñ Ð·Ð½Ð°ÑÐ¸Ð¼Ð¾ÑÑÑ Ð²ÑÐ¿Ð¾Ð»Ð½ÑÐµÐ¼ÑÑ Ð¿ÑÐ¾ÑÐµÐ´ÑÑ Ð¸Ð½Ð²ÐµÐ½ÑÐ°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸. ÐÑÑÐ²Ð»ÐµÐ½Ñ Ð¿ÑÐ¸ÑÐ¸Ð½Ñ Ð·Ð°ÑÐ¾Ð²Ð°ÑÐ¸Ð²Ð°Ð½Ð¸Ñ. ÐÐ°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÑÐµÑÐ° ÑÐ¾Ð²Ð°ÑÐ½ÑÑ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¹.
description: The aim of this work lie in explaining the logic and mechanisms inventory of resources of the enterprise, and how the quality of performance of inventory affect the organization. The thesis considers tool - inventory as part of the system of inventory management. In the Theoretical part of this work, the detailed mechanisms of the inventory of the organization. The basic equations and definitions on the topic. Based on the data of the enterprise the analysis of the organization, the inventory "TD Crystal". Given the results of the inventory in the accounting records. Reflected the practical significance of procedures performed inventory organization. Identify the causes of overstocking. Recommendations for improving the system of recording of stock transactions.
Stars lensed by the Supermassive Black Hole in the center of the Milky Way: predictions for future high-resolution instruments
Creators: name: Michałowski, Michał
name: Mróz, Przemek
Publisher: name: Zenodo
Year: 2022
Subjects: Lensing
Black hole
Galactic centre
Extremely Large Telescope
Thirty Meter Telescope
Giant Magellan Telescope
James Webb Space Telescope

description: Gravitational lensing is an important prediction of general relativity, providing both its test and a tool to detect faint but amplified sources and to measure masses of lenses. For some applications, (e.g., testing the theory), a point source lensed by a point-like lens would be more advantageous. However, until now only one gravitationally lensed star has been resolved. Future telescopes will resolve very small lensing signatures for stars orbiting the supermassive black hole (SMBH) in the center of the Milky Way. The lensing signatures, however, should be easier to detect for background stars. I will show the prediction that the Extremely Large Telescope (ELT), Thirty Meter Telescope (TMT), and Giant Magellan Telescope (GMT) will resolve the lensed images of around 100 stars in the background of the SMBH. The James Webb Space Telescope (JWST) will likely be limited by the confusion caused by stars near the Galactic center. I will also describe what observational characteristics are needed to achieve this (resolution and depth). Finally, I will discuss other observational signatures of lensed stars, which could be searched for with high-resolution instruments.
description: {"references": ["Micha\u0142owski M. J., Mr\u00f3z P., 2021, Astrophysical Journal Letters, 915, L33, Stars lensed by the supermassive black hole in the center of the Milky Way: predictions for ELT, TMT, GMT, and JWST"]}
title: ÐÑÑÐ¾ÑÐ¸Ñ ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÐºÐ¸Ð½ÐµÐ¼Ð°ÑÐ¾Ð³ÑÐ°ÑÐ°
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÑ Ð­Ð½ÑÑÐ½Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÑÐ¾Ð²ÐµÑÑÐºÐ¾Ðµ ÐºÐ¸Ð½Ð¾
Ð´Ð¾ÑÐµÐ²Ð¾Ð»ÑÑÐ¸Ð¾Ð½Ð½Ð¾Ðµ ÐºÐ¸Ð½Ð¾
ÐºÐ¸Ð½Ð¾Ð¸Ð½Ð´ÑÑÑÑÐ¸Ñ XX Ð²ÐµÐºÐ°
Ð¡ÐµÑÐ³ÐµÐ¹ ÐÐ¾Ð½Ð´Ð°ÑÑÑÐº

description: Ð¡Ð¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ðµ ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ðµ ÐºÐ¸Ð½Ð¾ Ð¿ÐµÑÐµÐ¶Ð¸Ð²Ð°ÐµÑ ÑÑÑÐµÐ¼Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð¿Ð¾Ð´ÑÐµÐ¼ Ð¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ðµ. ÐÐ¾ ÑÐ°Ðº Ð±ÑÐ»Ð¾ Ð½Ðµ Ð²ÑÐµÐ³Ð´Ð°. Ð¡ÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¸Ðµ ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÐºÐ¸Ð½Ð¾ Ð¿ÑÐ¾ÑÐ¾Ð´Ð¸Ð»Ð¾ Ð¾ÑÐµÐ½Ñ Ð´Ð¾Ð»Ð³Ð¾ Ð¸ ÑÑÐ¶ÐµÐ»Ð¾, Ð¿Ð¾ÑÐºÐ¾Ð»ÑÐºÑ Ð²ÐµÑÑ Ð·Ð°Ð¿Ð°Ð´Ð½ÑÐ¹ Ð¼Ð¸Ñ ÑÐ¶Ðµ Ð³Ð¾ÑÐ´Ð¸Ð»ÑÑ ÑÐ²Ð¾Ð¸Ð¼ ÐºÐ¸Ð½Ð¾Ð¸ÑÐºÑÑÑÑÐ²Ð¾Ð¼. ÐÐ¾ÑÑÐ¾Ð¼Ñ ÑÐµÐ¼Ð° Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ Ð°ÐºÑÑÐ°Ð»ÑÐ½Ð° Ð² Ð´Ð°Ð½Ð½Ð¾Ðµ Ð²ÑÐµÐ¼Ñ, Ð²Ð°Ð¶Ð½Ð¾ Ð·Ð½Ð°ÑÑ Ð¿ÑÑÑÑ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÐºÐ¸Ð½Ð¾Ð¸ÑÐºÑÑÑÑÐ²Ð°. Ð¦ÐµÐ»Ñ ÑÐ°Ð±Ð¾ÑÑ: Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÐºÐ¸Ð½Ð¾Ð¸Ð½Ð´ÑÑÑÑÐ¸Ð¸ Ð Ð¾ÑÑÐ¸Ð¸, Ð²ÑÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ Ð²Ð°Ð¶Ð½ÑÑ Ð¿ÐµÑÑÐ¾Ð½ ÐºÐ¸Ð½Ð¾Ð¸ÑÐºÑÑÑÑÐ²Ð°. Ð¡ÑÑÑÐºÑÑÑÐ° ÑÐ°Ð±Ð¾ÑÑ: ÑÐ°Ð±Ð¾ÑÐ° ÑÐ¾ÑÑÐ¾Ð¸Ñ Ð¸Ð· Ð²Ð²ÐµÐ´ÐµÐ½Ð¸Ñ, ÑÑÐµÑ Ð³Ð»Ð°Ð², Ð·Ð°ÐºÐ»ÑÑÐµÐ½Ð¸Ñ, ÑÐ¿Ð¸ÑÐºÐ° Ð»Ð¸ÑÐµÑÐ°ÑÑÑÑ (34 Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ°). Ð Ð¿ÐµÑÐ²Ð¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð° Ð¸ÑÑÐ¾ÑÐ¸Ñ ÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÐºÐ¸Ð½ÐµÐ¼Ð°ÑÐ¾Ð³ÑÐ°ÑÐ° Ð² Ð´Ð¾ÑÐµÐ²Ð¾Ð»ÑÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð¿ÐµÑÐ¸Ð¾Ð´. ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð° Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ ÑÐ°ÐºÐ¸Ñ Ð·Ð½Ð°ÐºÐ¾Ð²ÑÑ ÑÐ¸Ð³ÑÑ Ð² Ð¸ÑÑÐ¾ÑÐ¸Ð¸ ÐºÐ¸Ð½Ð¾, ÐºÐ°Ðº Ð. ÐÐ¾Ð·Ð¶ÑÑÐ¸Ð½, Ð. Ð¥Ð°Ð½Ð¶Ð¾Ð½ÐºÐ¾Ð², Ð. ÐÐ°ÑÑÑ, Ð¯. ÐÑÐ¾ÑÐ°Ð·Ð°Ð½Ð¾Ð². ÐÑÐ¾ÑÐ°Ñ Ð³Ð»Ð°Ð²Ð° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ¾ÑÐ¸Ð¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð¡Ð¾Ð²ÐµÑÑÐºÐ¾Ð³Ð¾ ÐºÐ¸Ð½ÐµÐ¼Ð°ÑÐ¾Ð³ÑÐ°ÑÐ°, ÐºÐ°Ðº Ð¶ÐµÐ¼ÑÑÐ¶Ð¸Ð½Ñ Ð¸ÑÐºÑÑÑÑÐ²Ð°. Ð¢ÑÐµÑÑÑ Ð³Ð»Ð°Ð²Ð° ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ ÐºÐ¸Ð½ÐµÐ¼Ð°ÑÐ¾Ð³ÑÐ°ÑÐ° Ð² Ð¿ÐµÑÐ¸Ð¾Ð´ XX-XXI Ð²ÐµÐºÐ¾Ð².
Le galassie libellula: grandi, leggere e resistenti
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2015

Confermata l’esistenza delle UDG, Ultra Diffuse Galaxies, sparsi agglomerati di stelle che devono ospitare in proporzione molta  materia oscura per poter stare assieme. «Se la Via Lattea fosse un mare, allora queste galassie sarebbero nuvole», spiega Pieter van Dokkum della Yale University
Additional file 1 of Immunization data quality and decision making in pertussis outbreak management in southern Ethiopia: a cross sectional study
Creators: name: Argaw, Mesele Damte
name: Desta, Binyam Fekadu
name: Tsegaye, Zergu Taffesse
name: Mitiku, Aychiluhim Damtew
name: Atsa, Afework Ayele
name: Tefera, Bekele Belayihun
name: Rogers, Deirdre
name: Teferi, Ephrem
name: Abera, Wondwosen Shiferaw
name: Beshir, Ismael Ali
name: Kora, Zelalem Abera
name: Setegn, Sisay
name: Anara, Amare Assefa
name: Sinamo, Tadelech
name: Muloiwa, Rudzani
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 1. The Ethiopian vaccination schedule of routine EPI, September 2019
title: Ð¡Ð¸ÑÑÐµÐ¼Ð° ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾ÑÐµÐ·Ð¾Ð¼ Ð¿ÑÐµÐ´Ð¿Ð»ÐµÑÑÑ Ñ ÑÑÐ½ÐºÑÐ¸ÐµÐ¹ ÑÐ³Ð¸Ð±Ð°Ð½Ð¸Ñ ÐºÐ¸ÑÑÐ¸
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: Ð¡ÑÑÑÑ, ÐÑÑÐµÐ¼
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: ÐÑÐ¾ÑÐµÐ·Ñ
ÐÐµÐ´Ð¸ÑÐ¸Ð½ÑÐºÐ¸Ðµ Ð¿ÑÐ¸Ð±Ð¾ÑÑ, Ð°Ð¿Ð¿Ð°ÑÐ°ÑÑ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ
Ð¿ÑÐµÐ´Ð¿Ð»ÐµÑÑÐµ
ÑÐ³Ð¸Ð±Ð°Ð½Ð¸Ðµ ÐºÐ¸ÑÑÐ¸

description: ÐÐ±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð° Ð°ÐºÑÑÐ°Ð»ÑÐ½Ð¾ÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¸Ð·Ð²ÐµÑÑÐ½ÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾ÑÐµÐ·Ð¾Ð¼. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð¾Ð±Ð·Ð¾Ñ Ð¸Ð·Ð²ÐµÑÑÐ½ÑÑ Ð¿ÑÐ¾ÑÐµÐ·Ð¾Ð² Ð¿ÑÐµÐ´Ð¿Ð»ÐµÑÑÑ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð·Ð°ÑÑÐ±ÐµÐ¶Ð½ÑÑ Ð¸ Ð¾ÑÐµÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ ÑÐ¸ÑÐ¼-Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´Ð¸ÑÐµÐ»ÐµÐ¹. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¸Ñ ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ñ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾ÑÐµÐ·Ð° Ð¿ÑÐµÐ´Ð¿Ð»ÐµÑÑÑ Ñ ÑÑÐ½ÐºÑÐ¸ÐµÐ¹ ÑÐ³Ð¸Ð±Ð°Ð½Ð¸Ñ ÐºÐ¸ÑÑÐ¸, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½ Ð¼ÐµÑÐ¾Ð´ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾ÑÐµÐ·Ð¾Ð¼ Ð¿ÑÐµÐ´Ð¿Ð»ÐµÑÑÑ. Ð¡ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð° ÑÑÑÑÐºÑÑÑÐ½Ð°Ñ ÑÑÐµÐ¼Ð° ÑÐ¸ÑÑÐµÐ¼Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾ÑÐµÐ·Ð¾Ð¼ Ð¿ÑÐµÐ´Ð¿Ð»ÐµÑÑÑ, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° ÐºÐ¸Ð½ÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ°Ñ ÑÑÐµÐ¼Ð° Ð·Ð°Ð´Ð°ÑÑÐµÐ³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°. ÐÑÐ±ÑÐ°Ð½Ñ Ð¿ÑÐ¸Ð²Ð¾Ð´Ñ ÑÐ³Ð¸Ð±Ð°Ð½Ð¸Ñ Ð¸ ÑÐ¾ÑÐ°ÑÐ¸Ð¸ Ð¸ÑÐºÑÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ ÐºÐ¸ÑÑÐ¸ Ð¸ ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½Ð° Ð¸Ñ Ð¼Ð¾ÑÐ½Ð¾ÑÑÑ.
Parabolic Symmetric Spaces
Creators: name: Zalabova, Lenka
Publisher: name: arXiv
Year: 2009
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C15; 53A40; 53C05; 53C35

description: We study here systems of symmetries on $|1|$--graded parabolic geometries. We are interested in smooth systems of symmetries and we discuss non--flat homogeneous $|1|$--graded geometries. We show the existence of an invariant admissible affine connection under quite weak condition on the system.
description: 15 pages
Mandibular bone and gingival epithelium during bisphosphonates treatment: an experimental study
Creators: name: Cutroneo, Giuseppina
name: Centofanti, Antonio
name: Vermiglio, Giovanna
name: Runci, Michele
name: Catalfamo, Luciano
name: De Ponte, Francesco Saverio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Biphosphonates; oral mucosa; ONJ.

description: Bisphosphonates (BP) are stable analogues of pyrophosphate with a P-C-P structure and 2 side chains attached to the carbon atom. Intravenous bisphosphonates are primarily used and effective in the management of cancer-related conditions in the context of solid tumors, such as breast cancer, prostate cancer, and lung cancer. Moreover bisphosphonates are subministred to patients with metabolic bone disease such as osteoporosis and Paget disease. Bisphosphonate-associated osteonecrosis of the jaws (BONJ) is a really complication of intravenous bisphosphonates therapy in patients with cancer. It is common knowledge that the jaws have a greater blood supply than other bones and a fasterbone turnover rate, related both to their daily activity and presence of teeth which mandates daily bone remodeling around the periodontal ligament; moreover bisphosphonates toxicity to epithelial cells has been well documented. On this basis, the aim of this experimental study is to evaluate the pathological changes of the mandibular bone and oral mucosa in rat treated with bisphosphonates. In details we have analyzed, by immunoistochemical and scanning electron microscopic methods, biopsy of mandibular bone and of gingival mucosa in rat treated with bisphosphonates after 7, 15, 30, 45, 60 days of assumption of drugs and after 7 and 30 days from the end of the treatment. Our results show great area demineralization bone mixed to normal bone, moreover in the demineralization bone it’s possible to observe numerous micro lacunae. In the correspondence samples of gingival epithelium we observe changes of histological structure and the disappearance of protein adhesion system cells to cells and cells to matrix. On this basis it is intriguing to speculate that the adverse effects of BP on oral epithelium may play a critical role in the initiation of BONJ an “outside-in” hypothesis.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Growth Effects of Foreign Direct Investments in Zimbabwe: Do Sources Matter?
Creators: name: Kudakwashe, Chinyanganya
name: Regret, Sunge
name: Kudakwashe, Chinyanganya
name: Regret, Sunge
Publisher: name: Unknown
Year: 2021
Subjects: subject: International Development
subject: International Relations/Trade
subject: FDI
subject: Economic growth
subject: Trade openness
subject: ARDL
subject: Zimbabwe

description: The study investigated foreign direct investment (FDI) growth effects in Zimbabwe using data spanning 1990-2019. FDI-led growth theories often view FDI as an enabler of economic growth. However, the extent may depend upon the source of FDI. Nonetheless, existing studies on Zimbabwe base their conclusions on aggregate FDI. Accordingly, we provide fresh evidence by disaggregating FDI inflows by sources. This is logical given the reality that FDI from different sources is heterogeneous. We used the Autoregressive-Distributed-Lag (ARDL) technique to estimate a time series model derived from neoclassical and endogenous growth models. Results indicated that FDI has a significantly positive growth effect. More importantly, we document that FDI sources do matter greatly. Specifically, FDI flows from Africa and Asia were found to have positive and significant growth effects. However, FDI from Europe and the United States has negative and insignificant impacts. We proffer two recommendations. Zimbabwe should attract more FDI from economies/regions in the vicinity of its level of development. Accordingly, Zimbabwe should rationally embrace the recently launched AfCFTA. It is vital to strike a balance between market deepening and promoting domestic production. Also, while most FDI from Asia is from is China, we urge Zimbabwe to provide a conducive environment to investors from the rest of Asia. This can be achieved through signing bilateral FDI agreements with Asian countries.
Sarcoglycan sub-complex and Satellite cells in masseter muscle of crossbite patients
Creators: name: Cutroneo, Giuseppina
name: Vermiglio, Giovanna
name: Favaloro, Angelo
name: Duca, Antonio
name: Magaudda, Emanuele
name: Speciale, Francesco Saverio
name: Piancino, Maria Grazia
name: Bracco, Pietro
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Sarcoglycans; masseter muscle; malocclusion; crossbite; satellite cells.

description: Crossbite is a lateral misalignment of the dental arches. Subjects with unilateral posterior crossbite exhibit different kinematics of the mandible during mastication when chewing on the affected side, resulting in an increased frequency of reverse chewing cycles; moreover, the masseter of the affected side results less active than the counterpart (Piancino et al., 2006). An our immunofluorescence study on masseter muscle of crossbite patients has shown that in the affected side there is a lower expression of muscle specific integrins than the counterpart (Cutroneo et al., 2012). So, we hypothesized that integrins could be correlated with contraction activity in mastication, maybe promoting the production of new muscle fibers. Another our tractography study on crossbite patients has shown an increment of muscle fibers number in non affected side. On this basis in the present work we investigated the number of satellite cells in masseter muscle of crossbite patients, both in affected and non affected side. Since the existence of a bidirectional signaling between integrins and sarcoglycans we have also investigated the expression of the sarcoglycan subcomplex. Results show that the number of satellite cells in non affected side is higher than affected side. Moreover, in according with our previous results about integrins, even the sarcoglycan sub-complex show to be less expressed in the affected side than the counterpart. These data support that in non affected masseter muscle a new fibers production activity takes place which, in turns, determines a muscular hyperplasia. Based on our results, the myogenesis in masseter muscle could be regulated by sarcoglycan and integrin protein systems.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Information Conservation, Entropy Increase and the Statistical Irreversibility for an Isolated System
Creators: name: Zhang, Qi-Ren
Publisher: name: arXiv
Year: 2009
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider the statistical irreversibility and its compatibility with the reversible dynamics. The role played by the observation is analyzed in detail. It makes our previous proof for the second law of thermodynamics clearer. On this basis, we emphasize the importance and wide applicability for the second law of thermodynamics. A new form of physics with this law being substituted by the principle of information conservation is suggested. By the way, we also solve the paradox of Schrödinger cat, and show that the universe will not go to the so-called heat death spontaneously.
description: 7 pages, 9 figure
Parkin isoforms expression in lung adenocarcinoma
Creators: name: D’Amico, A.G.
name: Maugeri, G.
name: Magro, G.
name: Salvatorelli, L.
name: Drago, F.
name: D’Agata, V.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Parkin isoforms; lung cancer cells; lung adenocarcinoma

description: PARK2, also known as parkin, is a gene mutated in autosomal recessive juvenile parkinsonism and it has been shown to exhibit E3 ubiquitin ligase activity. However it seems to fulfill also a wide spectrum of protective functions. Recent studies have demonstrated that parkin is an important regulator of process that maintain mitochondrial quality and it is also implicated in proteasomal degradation of toxic substrates. This gene has been also shown to be genetically altered and/or aberrantly expressed in a wide variety of human cancers including lung cancer (Cesari et al., 2003; Veeriah S. et al., 2010). Although many alternatively spliced isoforms have been identified, until now studies have been focused on the full-length isoform (D’Agata and Cavallaro, 2004). To characterize the role of parkin isoforms in lung tumorigenesis we analyzed their expression pattern in human lung adenocarcinomas. These data were correlated to their expression pattern either in human lung epithelial carcinoma (A549) or in human normal bronchial epithelial (BEAS-2B) cell lines. Western blot and immunofluorescence analyses were performed by using two antibodies recognizing different domains of the full length protein. Immunoblots showed that lung adenocarcinomas express parkin isoforms of 50, 37 and 20 kDa. Their expressions were significantly increased in A549 as compared to BEAS-2B, suggesting that parkin isoforms might be involved in cancer progression. In order to characterize some functions of these isoforms, both cell lines were cultured in complete medium or serum starved medium and treated with the proteasome inhibitor MG132 or with carbonyl cyanide 3- clorophenylhydrazone (CCCP), a uncoupling agent that dissipates the mitochondrial membrane. Data obtained revealed that each treatment affects pattern expression of parkin isoforms. These results suggest that some parkin isoforms might be molecular markers of lung adenocarcinoma.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Le nane bianche vanno in pensione in periferia
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2015

Gli scienziati hanno utilizzato Hubble per osservate le nane bianche nel cluster. Queste stelle morenti stanno migrando dal centro affollato verso orbite più ampie all'esterno. Gli astronomi conoscevano questo processo ma non l'avevano mai visto in azione
Additional file 2 of Immunization data quality and decision making in pertussis outbreak management in southern Ethiopia: a cross sectional study
Creators: name: Argaw, Mesele Damte
name: Desta, Binyam Fekadu
name: Tsegaye, Zergu Taffesse
name: Mitiku, Aychiluhim Damtew
name: Atsa, Afework Ayele
name: Tefera, Bekele Belayihun
name: Rogers, Deirdre
name: Teferi, Ephrem
name: Abera, Wondwosen Shiferaw
name: Beshir, Ismael Ali
name: Kora, Zelalem Abera
name: Setegn, Sisay
name: Anara, Amare Assefa
name: Sinamo, Tadelech
name: Muloiwa, Rudzani
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 2. Question on Quality for district level
The role of hyperfine mixing in $b\to c$ semileptonic decays of doubly-heavy baryons
Creators: name: Albertus, C.
name: Hernández, E.
name: Nieves, J.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We analyze the effects of hyperfine mixing in $b \to c$ semileptonic decays of doubly heavy baryons. We qualitatively confirm the results by W. Roberts and M. Pervin in Int. J. Mod. Phys. A, 2009, {\bf 24}: 2401-2413, finding that mixing has a great impact on those transitions. However, predictions without mixing differ by a factor of 2 and this discrepancy translates to the mixed case where large differences in decay widths are observed between the two calculations.
description: 3 latex pages. Talk given at The 5-th International Conference on Quarks and Nuclear Physics (QNP09), Beijing, September 2009
KIYIKO'T VA YALPIZDAN FOYDALANISH USULLARI
Creators: name: Shukurova, Shoxina
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqolada kiyiko’t va yalpizdan uy sharoitida damlama va qaynatmalar tayyorlashni o’rganish.Yangi texnologik usullarni qo’llab, kerakli ma’lumotga ega bo’lishimiz, damlama va qaynatma tayyorlashni bilib olishimiz mumkin.
Role of Adrenomedullin in LPS-mediated lung injury
Creators: name: David, Sabrina
name: Mosca, Claudia
name: Barbagallo, Ignazio
name: Rappa, Francesca
name: Peri, Giovanni
name: Farina, Felicia
name: Zummo, Giovanni
name: Cappello, Francesco
name: Li Volti, Giovanni
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Acute Respiratory Distress Syndrome; adrenomedullin; lipopolysaccharide; Hsp32; MAPK; p38MAPK.

description: Acute Respiratory Distress Syndrome is a life-threatening disease characterized by diffuse lung injury that leads to respiratory failure and death. Among various endogenous protective peptides, adrenomedullin (AM) has been demonstrated to play a major role. The aim of our study was to assess the significance of AM in the complex pathophysiological cascade underlying lipopolysaccharide (LPS) mediated inflammatory response. In the first set of our experiments we showed that LPS induced a significant increase in the activation of the mitogen-activated protein kinase (MAPK) transduction signals in epithelial respiratory cells. In particular, our results showed a time and dose dependent activation of ERK and JNK pathways. No significant changes were observed for p38MAPK phosphorylation. Luminex analysis further confirmed the significant increase of IL-6 release along with a significant increase of MCP-1 , VEGF and IL-8. Pre-treatment of cells with AM (0.5 and 1 ng/ml) showed that AM was able to prevent JNK and ERK phosphorylation. Such effect turned into a significant reduction of IL-6 and TNF- gene transcription and induction of heme oxygenase-1 (Hsp32). Taken all together our data suggest that AM may play a major role in reducing LPS mediated inflammatory response by reducing the activation of MAPK signal transduction pathway.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Nitric Oxide-mediated cytotoxic effect induced by zoledronic acid treatment on Human Gingival Fibroblasts
Creators: name: De Colli, M.
name: Zara, S.
name: Di Giacomo, V.
name: Patruno, A.
name: Gallorini, M.
name: Sancilio, S.
name: Zizzari, V.L.
name: Tetè, G.
name: Cataldi, A.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Zoledronic acid (ZA) belongs to bisphosphonates (BPs), drugs administered to treat resorptive bone diseases. Although ZA is largely used in the clinical practice, significant adverse effects of ZA, such as osteonecrosis of the jaw (ONJ), were recorded. The aim of this work was to evaluate the role of Nitric Oxide (NO) in the in vitro response of Human Gingival Fibroblasts (HGFs) to 1, 5, 10 and 100μM ZA. HGFs morphology was evaluated through phase contrast microscopy and live/ dead staining; MTT and ELISA assays were applied to measure cell viability, Collagen Type I and IL6 secretion. ROS production and mitochondrial membrane potential were evaluated by flow cytometry; NO production and NOS activity by spectrophotometric analysis; eNOS and nNOS expression by fluorescence microscopy. Viable fibroblasts are evidenced in control sample while floating dead cells and cells close to detachment phase in ZA treated sample along with decreased level of Collagen Type I. Control sample shows higher number of viable cells respect to ZA treated one and ROS production increases when ZA is added. Released NO in ZA treated sample appears higher and NO overproduction is related to increased nNOS activity. IL 6 secretion level is higher in ZA treated sample than in control one. Our results suggest ROS involvement in NO overproduction, due to nNOS recruitment, both at low and high doses. In turn, NO release seems to be able to trigger the inflammatory response only when high doses are administered.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Il primo quartetto di quasar
Creators: Elisa Nichelli
Publisher: name: Media Inaf
Year: 2015

Scoperto da un gruppo di astronomi del Max Planck Institute for Astronomy il primo quartetto di quasar a circa 10 miliardi di anni luce da noi. L'eccezionalità di un sistema simile potrebbe mettere in crisi i modelli di formazione delle strutture più massicce dell'Universo
Additional file 3 of Immunization data quality and decision making in pertussis outbreak management in southern Ethiopia: a cross sectional study
Creators: name: Argaw, Mesele Damte
name: Desta, Binyam Fekadu
name: Tsegaye, Zergu Taffesse
name: Mitiku, Aychiluhim Damtew
name: Atsa, Afework Ayele
name: Tefera, Bekele Belayihun
name: Rogers, Deirdre
name: Teferi, Ephrem
name: Abera, Wondwosen Shiferaw
name: Beshir, Ismael Ali
name: Kora, Zelalem Abera
name: Setegn, Sisay
name: Anara, Amare Assefa
name: Sinamo, Tadelech
name: Muloiwa, Rudzani
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 3. Question on Quality health facility level
title: ÐÑÐµÐ½ÐºÐ° ÑÐ²ÑÐ·Ð¸ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»Ð° Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÑÐ¼Ð¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¡Ð¸Ð·ÐµÐ²Ð°, Ð¢Ð°ÑÑÑÐ½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½ÑÐ¹ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»
Ð½ÐµÐ¼Ð°ÑÐµÑÐ¸Ð°Ð»ÑÐ½ÑÐµ Ð°ÐºÑÐ¸Ð²Ñ
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ÑÑÑÑÐºÑÑÑÐ½ÑÐ¹ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»
ÑÑÐ½Ð¾ÑÐ½ÑÐ¹ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÑÑÑÑ ÑÐ°ÑÐ¼Ð°ÑÐµÐ²ÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ: ÑÐ²ÐµÐ¹ÑÐ°ÑÑÐºÐ°Ñ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ñ Novartis, Ð½ÐµÐ¼ÐµÑÐºÐ°Ñ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ñ Bayer, ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¸Ðµ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ ÐÐ Â«Ð¤Ð°ÑÐ¼ÑÑÐ°Ð½Ð´Ð°ÑÑÂ» Ð¸ ÐÐÐ Â«ÐÑÐ¸ÑÐ¸ÑÐ°ÑÐ¼Â».
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ÐÑÐ»Ð¸ Ð¸Ð·ÑÑÐµÐ½Ñ ÑÐ¸Ð½Ð°Ð½ÑÐ¾Ð²ÑÐµ Ð¾ÑÑÐµÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ Ñ 2004 Ð³. Ð¿Ð¾ 2016 Ð³. ÐÐ»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»Ð° Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½ Ð¼ÐµÑÐ¾Ð´ VAIC, ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹: ROE, ROA, Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÑ ÑÑÑÐ´Ð°, ÑÐµÐ¼Ð¿ ÑÐ¾ÑÑÐ° Ð²ÑÑÑÑÐºÐ¸ Ð¾Ñ Ð¿ÑÐ¾Ð´Ð°Ð¶, ÑÐµÐ¼Ð¿ ÑÐ¾ÑÑÐ° Ð´Ð¾Ð±Ð°Ð²Ð»ÐµÐ½Ð½Ð¾Ð¹ ÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸. ÐÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð´Ð°Ð½Ð½ÑÐµ VAIC Ð¼Ð½Ð¾Ð¶ÐµÑÑÐ²Ð° ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¹ ÐºÐ°Ðº ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¸Ñ, ÑÐ°Ðº Ð¸ Ð·Ð°ÑÑÐ±ÐµÐ¶Ð½ÑÑ. ÐÐ»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ²ÑÐ·Ð¸ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»Ð° Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÑÐ¼Ð¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ Ð±ÑÐ» Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ ÐºÐ¾ÑÑÑÐ¸ÑÐ¸ÐµÐ½ÑÐ¾Ð² Ð¿Ð°ÑÐ½Ð¾Ð¹ ÐºÐ¾ÑÑÐµÐ»ÑÑÐ¸Ð¸, Ð·Ð° Ð¸ÑÐºÐ»ÑÑÐµÐ½Ð¸ÐµÐ¼ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÐµÐ¹ Ð¼Ð¾Ð»Ð¾Ð´Ð¾Ð¹ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ ÐÑÐ¸ÑÐ¸ÑÐ°ÑÐ¼ Ð² ÑÐ²ÑÐ·Ð¸ Ñ Ð½ÐµÐ´Ð¾ÑÑÐ°ÑÐ¾ÑÐ½ÑÐ¼ Ð¾Ð±ÑÐµÐ¼Ð¾Ð¼ Ð²ÑÐ±Ð¾ÑÐºÐ¸.
ÐÑÑÐ²Ð»ÐµÐ½Ð¾, ÑÑÐ¾ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½ÑÐ¹ ÐºÐ°Ð¿Ð¸ÑÐ°Ð» ÑÐ¾ÑÑÐ¸Ð¹ÑÐºÐ¸Ñ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ Ð² ÑÑÐµÐ´Ð½ÐµÐ¼ Ð²ÑÑÐµ, ÑÐµÐ¼ ÑÐ·Ð°ÑÑÐ±ÐµÐ¶Ð½ÑÑ Ð¸Ð·-Ð·Ð° Ð±Ð¾Ð»ÐµÐµ Ð½Ð¸Ð·ÐºÐ¸Ñ Ð·Ð°ÑÑÐ°Ñ Ð½Ð° ÑÑÑÐ´ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸ÑÑ Ð Ð¾ÑÑÐ¸Ð¸. VAIC Ð·Ð°ÑÑÐ±ÐµÐ¶Ð½ÑÑ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸Ð·ÑÐµÑÑÑ Ð±Ð¾Ð»ÑÑÐµÐ¹ ÑÑÐ°Ð±Ð¸Ð»ÑÐ½Ð¾ÑÑÑÑ.ÐÐ»Ñ ÑÑÐ´Ð° ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð° Ð´Ð¾ÑÑÐ°ÑÐ¾ÑÐ½Ð¾ ÑÐµÑÐ½Ð°Ñ ÑÐ²ÑÐ·Ñ Ð¼ÐµÐ¶Ð´Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÑÐ¼Ð¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ Ð¸ VAIC Ð·Ð° Ð¿Ð¾ÑÐ»ÐµÐ´Ð½Ð¸Ðµ 10 Ð»ÐµÑ.
ÐÐ½Ð¸Ð¼Ð°Ð½Ð¸Ðµ Ð¼ÐµÐ½ÐµÐ´Ð¶ÐµÑÐ¾Ð² Ðº Ð¾ÑÐµÐ½ÐºÐµ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°Ð¿Ð¸ÑÐ°Ð»Ð° Ð¼Ð¾Ð¶ÐµÑ Ð¿ÑÐ¸Ð²ÐµÑÑÐ¸ Ð² Ð´Ð°Ð»ÑÐ½ÐµÐ¹ÑÐµÐ¼ Ðº ÑÐ¾ÑÑÑ Ð¿ÑÐ¸Ð±ÑÐ»Ð¸ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ Ð¸, ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÐµÐ½Ð½Ð¾, ÑÐ¾ÑÑÑ ÐµÐµ ÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸.
Il lungo risveglio del magnetar
Creators: Marco Galliani
Publisher: name: Media Inaf
Year: 2015

Uno studio a guida italiana e con nutrita partecipazione di ricercatori dell'INAF rivela le inattese proprietà di di una stella di neutroni super magnetica, scoperta alcuni anni fa in vicinanza del buco nero supermassiccio al centro della Via Lattea
Circulating metabolites indicate differences in high and low residual feed intake Holstein dairy cows- Supplemental Tables
Creators: name: Martin, Malia J.
name: Pralle, Ryan S.
name: Bernstein, Isabelle R.
name: VandeHaar, Michael J.
name: Kent. A. Weigel
name: Zhou, Zheng
name: White, Heather M.
Publisher: name: Zenodo
Year: 2021

description: Supplemental tables for "Circulating metabolites indicate differences in high and low residual feed intake Holstein dairy cows". Supplemental Table S1: Differential pathways between inefficient (LE; n = 8) and efficient (HE; n = 8) multiparous dairy cows as determined by pathway enrichment analysis from the 39 differential blood plasma metabolites and Supplemental Table S2: Calculated ingredient composition and nutrient analysis of lactation diets across three replicated mid-lactation feed efficiency studies.
Physics results from dynamical overlap fermion simulations
Creators: name: Hashimoto, Shoji
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: I summarize the physics results obtained from large-scale dynamical overlap fermion simulations by the JLQCD and TWQCD collaborations. The numerical simulations are performed at a fixed global topological sector; the physics results in the theta-vacuum is reconstructed by correcting the finite volume effect, for which the measurement of the topological susceptibility is crucial. Physics applications we studied so far include a calculation of chiral condensate, pion mass, decay constant, form factors, as well as (vector and axial-vector) vacuum polarization functions and nucleon sigma term.
description: 15 pages, a plenary talk presented at the 26th International Symposium on Lattice Field Theory (Lattice 2008), Williamsburg, Virginia, USA, July 14-19, 2008
Morphology related functionality in Caco2/HT-29 co-culture cells: a versatile model of human intestinal epithelium
Creators: name: De Luca, Paola
name: Arnaboldi, Francesca
name: Maggioni, Margherita
name: Donetti, Elena
name: Fiorilli, Amelia
name: Ferraretto, Anita
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Human intestinal cell co-culture; proliferation rate; enzyme assays; TEER.

description: Caco2 and HT-29 cells represent two frequently used cell models of intestinal epithelium. Both cell lines consist of cells of tumour origin induced to differentiate but while Caco2 cells differentiate mainly toward absorptive entherocytes, HT-29 cells differentiate toward entero-endocrine/mucus secreting, goblet entherocytes (Zweibaum et al. 1991). Co-cultures of Caco2 /HT-29 cells, when completely characterized, could represent a more physiological model for drug absorption and intestinal tumor studies. Caco2/HT-29 co-culture at full confluency shows a proliferation rate, measured by tetrazolium colorimetric assay (MTT), intermediate to that of parental HT-29 and Caco2 cells. Protein content progressively increases with days of post confluence, corresponding to the presence of multilayers, as revealed by TEM. Alkaline phosphatase and sucrase-isomaltase are two known biochemical markers of intestinal cell differentiation. In Caco2/HT-29 co-cultures the ALP activity progressively increases while the sucrase-isomaltase activity decreases with days at post-confluence. These results are similar to the ones reported for the parental cell lines and reflect the development of a functionally differentiated epithelium, in agreement with the observed morphology. Trans electrical epithelial resistance (TEER), indicative of the barrier properties of the formed monolayer, increases with days at post confluence up to the 6th day. Taken together the present data identifies Caco2/HT-29 cocultures here analysed as a valid model of human intestinal epithelium, characterized by the presence of more than one intestinal citotype thus with wide possibilities of use for all the studies needing a physiological model as much as possible comparable to human intestine.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014
Additional file 1 of Analysing the protection from respiratory tract infections and allergic diseases early in life by human milk components: the PRIMA birth cohort
Creators: name: van Stigt, Arthur H.
name: Oude Rengerink, Katrien
name: Bloemenkamp, Kitty W. M.
name: de Waal, Wouter
name: Prevaes, Sabine M. P. J.
name: Le, Thuy-My
name: van Wijk, Femke
name: Nederend, Maaike
name: Hellinga, Anneke H.
name: Lammers, Christianne S.
name: den Hartog, Gerco
name: van Herwijnen, Martijn J. C.
name: Garssen, Johan
name: Knippels, Léon M. J.
name: Verhagen, Lilly M.
name: de Theije, Caroline G. M.
name: Lopez-Rincon, Alejandro
name: Leusen, Jeanette H. W.
name: van’t Land, Belinda
name: Bont, Louis
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Figure S1. Study activities overview: overview of all study activities. Figure S2. Sample processing in PRIMA human milk cohort: A) Human milk samples are centrifuged for 10 min at 600 g in order to remove the cream (layer on top, indicated in yellow) and cells (collected in pellet on the bottom, indicated in dark grey). B) Milk supernatant is collected by pipetting through cream layer without disturbing the cell pellet and subsequently transferred into a new tube. C) Collected 600 g supernatant is again centrifuged for another 10 min at 600 g. D) Milk supernatant is collected by pipetting through the residual cream and transferred to and aliquoted into clean cryotubes, and stored at -80 °C until further analysis. E) The cream layer is removed without disturbing the cellular pellet and transferred into cryotubes stored at -80 °C for further analysis. F) 20 mL PBS is added to rinse and cells are spun at 600 g for 10 min, after which the supernatant is discarded and cells are kept on ice until further processing for analysis G). Milk EVs are processed further according to the Zonneveld protocol at 3000 g.
Integrins and Cadherins could be important regulators of osteogenic differentiation and bone formation in dental stem cells
Creators: name: Di Benedetto, A.
name: Posa, F.
name: Carbone, C.
name: Brunetti, G.
name: Lo Muzio, L.
name: Colucci, S.
name: Grano, M.
name: Mori, G.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Stem cells; mesenchymal stem cells; bone regeneration; Integrin; Cadherin.

description: Regenerative medicine aims to translate the regeneration of tissues and organs into clinical application. Numerous studies have reported beneficial effects of Adult stem cells therapy in the treatment of disease and disabilities. New sources of mesenchymal stem cells (MSCs) are emerging in adult organisms, and dental tissues, that are easily accessible, have been identified as a source of postnatal MSCs capable of self-renewal and multipotency. Dental Follicle Stem Cells (DFSCs) isolated from tooth buds of healthy paediatric patients showed ≥95% expression of stemness makers (CD73, CD90, CD146, CD44, CD105, and HLA-I) [1]. Moreover DFSCs differentiated into osteoblastlike cells, produced mineralized matrix nodules and expressed typical osteoblastic markers. Cell interactions with extracellular matrix (ECM) and neighbor cells are critical for tissue morphogenesis and architecture, and are mediated by two classes of adhesion molecules, respectively Integrins and Cadherins, which also act intracellularly by modulating crucial pathways of proliferation and differentiation. Thus, in this study, DFSCs were characterized for the expression of adhesion molecules Cadherins and Integrins. In basal conditions DFSCs expressed higher levels of N-Cadherin and Cadherin-11 in comparison to E-Cadherin and P-Cadherin, which were low expressed. The examined Cadherins showed different behaviours during DFSCs osteogenic differentiation: N-cadherin expression was high during the first steps, while decreased at the later times; Cadherin-11 progressively increased; E-Cadherin and P-Cadherin did not change a Cadherin profile reflecting the osteoblastic commitment of the cells. DFSCs expressed the Integrin subunits alpha V, beta 3, alpha 5, and beta 1 in basal undifferentiated conditions but their expression increased time-dependently under osteogenic treatment. In addition we found that the subunits alpha V and beta 3 associated and formed the functional integrin, which localized at the focal adhesion in response to osteogenic trigger; similarly, alpha 5 and beta 1 subunits were found to associate and localize at the cell borders mostly in differentiated cells. Finally we found that osteogenic differentiation of DFSCs was prompted out by seeding the cells on ECM protein coated surfaces. Functional tissue engineering for bone regeneration requires the appropriate combination of MSCs with biocompatible scaffolds, thus acting on cell surface and ECM molecules could optimize osteogenic differentiation of MSCs and contribute to the successful regeneration of damaged bone tissue.
description: Italian Journal of Anatomy and Embryology, Vol 119, No 1 (Supplement) 2014