cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Behavior of wood shear walls subjected to nonlinear cyclic loading
Creators: name: Talbot, Kenneth C
Publisher: name: University of Utah
Year: 2012
Subjects: House construction
Paneling

description: Nails have been the primary connector type used to fasten wood sheathing to wood frames, which are designed to resist the lateral loads on the structure. Numerous tests have been conducted using monotonic and cyclic loading protocols to determine strength and behavior properties of wood shear walls that have been fastened with  pneumatic and hand driven nails. Pneumatic nailers now make it possible to use staples  as a connector in wood shear walls. However, there has been only one set of tests conducted on this type of wall to determine their strength and behavior. Staple strength and behavior patterns have been examined, and based on those relationships allowable design loads for stapled shear walls were developed.  This research paper reports the tests done on a total of 12 shear wall panels with four groups of panels consisting of 3 foot, 4 foot, 8 foot, and 12 foot lengths in each group. The frames of each panel were hand nailed together. The sheathing was then attached to the frames with staples. Each panel tested had test variations, which was  expected to improve the strength of the panel and increase the ductility of the panel as it  was pushed beyond its linear range. The panels were tested using a cyclic loading protocol based on displacement, which was developed by the Structural Engineers Association of Southern California, and is required by the ICBO for acceptance of wood shear wall panel strength parameters.
Comparison of vascular networks, water use and growth rates in two tree species of contrasting functional type
Creators: name: von Allmen, Erica Isele
Publisher: name: University of Utah
Year: 2012
Subjects: Diffuse porous
Ecohydrology
Metabolic scaling in plants
Plant water transport
Ring porous
Sapflow
Quercus gambelii
Acer grandidentatum

description: The curious pattern of metabolic rate scaling with mass to the ¾ power has been observed across organisms and has eluded biologists for nearly a century. Metabolic scaling in trees has recently attracted attention as scientists try to model ecosystem dynamics of the hydrologic cycle and the carbon cycle. In this study, we attempt to gain greater understanding about the mechanical and hydraulic principles that govern vascular networks, how water transport through these networks scale with tree size, and how water use relates to growth rates in functionally diverse ring-porous Quercus gambelii and diffuse-porous Acer grandidentatum. We parameterized a numeric network model with species-specific vascular and structural characters to predict water use and growth rate scaling with tree size. The network model currently is confined to optimal water supply. To better understand water use and growth rate patterns during variable season conditions, we measured whole-tree sapflow, conductance and growth rates over one growing season in these two species. The numeric network model did exceptionally well at predicting species-specific scaling of water use and growth rates with tree size. In addition, it accurately predicted relative water use per species. Comparison of these two sympatric species over the growing season suggested that ring-porous Q. gambelii has relatively stable (isohydric) water use patterns and similar growth rates to diffuse-porous A. grandidentatum which has more flexible water use strategy leading to variable growth rates. These two species are able to be co-dominant in this region due to unique water use niches and vasculature. The accuracy of the numeric model predictions tested here suggest that scaling models such as these could be valuable in making ecohydrological predictions enabling the prediction of water use and growth rates with tree size and scaling this up to the stand and ecosystem level. We hope this work infusing hydraulic and mechanical constraints driving water use and growth rates of individuals within and between species contributes to better understanding of processes that effect predictions of ecosystem challenges under global change.
Novel neutrophil agonists : oxidatively-fragmented phosphatidylcholines
Creators: name: Smiley, Patricia Louise
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: A variety of pathologic processes including ischemia and reperfusion-associated injury, Adult Respiratory Distress Syndrome, and chronic inflammation are associated with the sequestration and inappropriate activation of neutrophils (PMN). PMN contribute to tissue injury by degranulating to release of lytic components and by generating massive amounts of free radicals upon activation of the neutrophil respiratory burst. In addition to the activation of PMN, these pathologic processes are associated with the generation of reactive oxygen species, molecules that are efficient at modifying the structure of macromolecules, incuding cell membranes, proteins, and nucleic acids. Due to their abundance and susceptibility to oxidation, the polyunsaturated fatty acids present in the cell membrane phospholipids are primary targets for free radical-mediated oxidation, with subsequent peroxidation, bond rearrangement, degradation, and hydroxy lation.  This dissertation presents data supporting the hypothesis that oxidative modification of membrane phospholipids may alter their structures so they are able to bind to and activate receptors present on the neutrophil surface for a potent phospholipid autocoid, platelet-activating factor (PAF). PAF mediates a variety of effects, including profound hypotension, increased vascular permeability, and activation of inflammatory cells. The model oxidatively-fragmented phospholipid, l-palmitoyl-2(-5-oxovaleroyl)-phosphatidylcholine was shown to stimulate neutrophil function through the PAF receptor. Additionally, oxidatively-fragmented phospholipids formed during unregulated oxidation of the phospholipid hydroperoxide, l-palmitoyl-2-(15-hydroperoxyeicosatetraenoyO-phosphatidylcholine were shown to exhibit PAF-like activity. One of these bioactive products was identified by gas chromatography/mass spectrometry as, l-paimitoyl-2-propionoyl-GPC, an oxidized phospholipid with an exceedingly short sn-2 residue. Additionally, bioactive compounds generated upon unregulated oxidation were substrates for the plasma PAF acetylhydrolase, an enzyme that circulates in whole blood and degrades phospholipids with short sn-2 residues, such as PAF. This enzyme may help limit the injury mediated by these phospholipids by ablating their activity should they occur in vivo.  Finally, the cell membrane phospholipids of the neutrophils themselves may be targets for oxidative modification. Oxidized phosphatidylcholines with PAF-like bioactivity were generated upon peroxidation of the neutrophil cell membrane phospholipids. This activity was mediated by species with sn-\ ether linkages, although there actually apprears to be selective oxidation for PMN membrane phosphatidylcholines with sn-1 ester-linked residues.
Neo-shamanism as a healing system: enchanted healing in a modern world
Creators: name: Braun, Shelly Beth
Publisher: name: University of Utah
Year: 2012
Subjects: Alternative spirituality
Complementary and alternative medicine
Modern shamanism
Neo-shaman(ism)
Shamansim
Spiritual healing

description: This dissertation explores the idea of enchantment, disenchantment, and reenchantment, following Weber, at the intersection of traditional healing and modern  society in the spiritual practice of neo-shamanism. Neo-shamanism as a healing system in the US is explored ethnographically. Neo-shamanism is the application and practice of shamanic techniques in  contemporary Western society and functions as a system of healing alternative to biomedicine. Following traditions of ancient shamanism from around the world, modern  individuals use an altered state of consciousness to get information from extra-material realms (referred to as nonordinary reality) to effect healing for themselves, others, society, and the planet. The neo-shamanic worldview holds that the extra-material world is as real as the material; the physical and spiritual are merged and can be utilized to assist humans. This stands in conflict with what Weber referred to as modernity's  disenchanted worldview -a Cartesian world where only the material is real. Modernity also places high emphasis on the individual. The modern self seeks autonomous selfcultivation, aspires to ground identity within, and desires to exercise independence, authority, choice, and expressivity. This is in contrast to the traditional self, which was embedded in the established order of things.
Sonnenfleckenzeichnung Nr. 23608.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.03.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Cryokinetics and spin quenching in the N2 adsorption onto rhodium cluster cations
Creators: name: Ehrhard, Amelie A.
name: Klein, Matthias P.
name: Mohrbach, Jennifer
name: Dillinger, Sebastian
name: Niedner-Schatteburg, Gereon
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: The kinetics of N2 adsorption onto gas phase Rhi+ clusters (i = 5–15) within 26 K He buffer gas have been investigated by Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry, with particular focus to clusters i = 5,6,7,9. The adsorption limits m = mmax of [Rhi(N2)m]+ clusters strongly depend on the size of the clusters. Some Rhi+ clusters reveal an intermittent adsorption limit mx, which implies a rough cluster surface. Most of the clusters reveal smooth surfaces, which consist of Rh atoms with similar next neighbour coordination. The kinetic fits and relative rate constants reveal the sequential adsorption of N2 as the only significant reaction channel. In some cases, we find N2 desorption steps at high N2 loads indicating adsorption–desorption equilibria. For these steps, we determined Gibbs energies from the relative rate constants. We observed a significant reluctance towards N2 adsorption for the Rh5+ cluster, indicated by significant desorption at low N2 coverage. Our DFT calculations model the energetics of the N2 adsorption onto Rh5+ in terms of coverage dependent ‘spin valley’ curves, and we conclude that an adsorption induced spin quenching takes place upon considerable N2 coverage, m > 4.
Some aspects of credit for Indian tribes in Utah, Nevada, Southern Idaho, and Northern California
Creators: name: White, John Edward
Publisher: name: University of Utah
Year: 2012
Subjects: Indians of North America
Economic conditions

description: Interest in some phase of the Indian life is almost  universal throughout America. Students of Anthropology; and history are interested in their origin, legends, and cultural attainments; statesmen and economists in their history and economic status while sociologists and public spirited citizens are concerned with the study of their social welfare and advancement.  In presenting and analyzing some of the phases of the  economy of the various Indian groups in the Basin-Plateau Region and parts of northern California, an approach to the problem must of necessity come through an understanding of the underlying conditions which have created the situation.   In order that this viewpoint may be clarified, an attempt  will be made to present a resume of the social and economic background of these Indians and the use which they made of their natural resources; of the cumbersome situations resulting from confused and entangled conceptions of Indian and European culture; also, to present a dearer picture of Indian credit  and its use, and to show the accomplishments of these people through the use of Federal-Finance;d credit facilities made available to them.  The problem in a broader sense involves queries ass  What are the Indians' credit needs? What is the present  picture of Indian life? Are Indian loans being repaid?  What can be learned from the study of Indian credit operations with special reference to credit facilities made  available to Indians through recent Federal legislation?  What progress is being made in cooperative marketing with Indian groups?
eCharge4Drivers project - D8.2 eCharge4Drivers website
Creators: name: Weeks, Sara Jane
name: Coppola, Carla
name: Somoza, Laura Babío
name: Basdeki, Barbara
name: Georgiou, Niki
Publisher: name: Zenodo
Year: 2021

description: eCharge4Drivers’ website www.echarge4drivers.eu has been designed to represent the project in a complete, transparent and user-friendly manner. The website will be an important dissemination tool for eCharge4Drivers, as it will contain all the necessary information on the project and will be constantly updated with the latest information. It will be the project’s main channel to the outside world, providing information on eCharge4Drivers objectives, partners, methodologies, results, publications, news and success stories.
Sonnenfleckenzeichnung Nr. 23607.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.03.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Pelidnota bleuzeni
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Pelidnota
Pelidnota bleuzeni

description: Pelidnota bleuzeni (Bouchard, 2003)
Chalcoplethis bleuzeni Bouchard 2003: 105 (French Guiana)
Distribution. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Brokopondo.). French Guiana: Bouchard 2003: 105 (as Chalcoplethis bleuzeni); Soula 2008: 34 (as Strigidia bleuzeni), 2010a: 55; Moore et al. 2017: 167. Venezuela (EO): Moore et al. 2017: 167 (EO).
Note. Soula (2009: 115) synonymizes the genus Strigidia with the genus Pelidnota and gives a list of the new combinations which are thus created. The species Pelidnota bleuzeni is apparently accidentally omitted from that list.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 147, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 23582.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.02.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 23575.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.02.1971, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 23637.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.04.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Regulation of nuclear envelope breakdown by the nuclear pore complex
Creators: name: Prunuske, Amy Jeanette
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: In higher eukaryotes, each time a cell divides dramatic changes occur at the nuclear periphery. The nuclear envelope, nuclear pore complexes, and nuclear lamina must disassemble to allow the mitotic spindle access to the genomic DNA, but little is known about the mechanisms required for these breakdown events. In order to biochemically dissect these events, we have optimized an assay to study nuclear disassembly in vitro using Xenopus egg extracts. One of the early events in nuclear envelope breakdown is disassembly of the nuclear pore complexes suggesting that the nuclear pores may be an important organizing center of mitotic events. We have identified a role for two nuclear pore proteins, Nup153 and Nup358/RanBP2, in recruiting the COPI coatomer complex to the nuclear envelope during nuclear disassembly. Adding antibody specific to either of these nuclear pore proteins individually inhibits nuclear disassembly, suggesting the nucleoporins are required in a nonredundant manner. The zinc finger domains within these nucleoporins appear to be the critical determinants for their role in nuclear envelope breakdown, since addition of recombinant zinc finger fragments derived from either pore protein alters COPI recruitment to the nuclear envelope and interferes with nuclear envelope breakdown. The localization of Nup153 and Nup358 to the nuclear basket and cytoplasmic filaments of the nuclear pore, respectively, suggests that recruitment of COPI to both faces of the pore is important. The COPI complex is known to have a role in vesicle trafficking from the Golgi to the ER and may play a similar role at the nuclear envelope during disassembly. The zinc finger fragments also prevent disassembly of the nuclear lamina, suggesting that recruitment of COPI to the nuclear envelope may be critical for coordinating dispersal of the membrane with other cell cycle events. Nuclei disassembled during prophase must then be efficiently reassembled during anaphase. Using dominant negative recombinant protein fragments, we have found that Nup153 interacts with regulators required for nuclear assembly and DNA replication. These results provide new information about the critical components of nuclear assembly and disassembly and lay the foundation for a better understanding of how these processes are regulated.
Pelidnota cayennensis F. Bates 1904
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Pelidnota
Pelidnota cayennensis

description: Pelidnota cayennensis F. Bates, 1904
Pelidnota cayennensis F. Bates 1904: 269 (Guyana? - LECTOTYPE)
Distribution. Guyana: Bodkin 1919: 217; Soula 2009: 107 (designation LECTOTYPE Pelidnota cayennensis). French Guiana: Ohaus 1913: 499 (as P. laevissima cayennensis), 1934: 80 (as P. laevissima cayennensis); Blackwelder 1944: 237 (as P. laevissima cayennensis); Machatschke 1972: 22 (as P. (Pelidnota) laevissima cayennensis); Brûlé et al. 2011a: 192 (as P. laevissima cayennensis), 2014: 182 (as P. laevissima cayennensis); Brûlé and Dalens 2012b: 37; Moore et al. 2017: 173. “Guianas”: F. Bates 1904: 269. Venezuela (EO): F. Bates 1904: 269; Moore et al. 2017: 173 (EO). Other: Soula 2010a (not mentioned).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 147, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 23548.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.01.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Adaptive responses to scarcity among lactating desert women
Creators: name: Hodson, Gabrielle Stella
Publisher: name: University of Utah
Year: 2012
Subjects: Adaptation
Alloparenting
Energy expenditure
Hot-cold syndrome
Lactation

description: Natural selection favors individuals with those adaptive traits that maximize their reproductive success. Effective heat acclimatization in the desert requires conserving body water with a simultaneous reduction in body heat by engaging in adaptive strategic behaviors. The adaptive strategies in response to water and food deprivation that contribute to successful breast milk production among lactating desert women have not been adequately researched. This study compared the rates of energy expenditure between lactating and non lactating desert women in Hidalgo, Mexico, indicating a significantly consistent physiological reduction in the rate of energy expenditure among lactating women as compared to non lactating women. Time allocation data confirmed their exploitation of allomothers with the dominant help being provided by their older female children. The cooling of their bodies prior to breast-feeding, a behavior associated with the "hot breast milk" notion of the hot-cold syndrome, reduces their body heat and ensures maternal relaxation essential to successful breast milk synthesis. The influence of the hormone prolactin during lactation stimulated by increased frequency of breast-feeding, enhances their body water retention, thus improving the cost efficiency of breast milk production for these desert women with limited access to clean water. These adaptive behavioral and physiological strategies that improve infant nutrition and maternal hydration in hot dry climates might prove to be vital to human survival in a future of climatic change and ecological decline.
BIOTECHNOLOGY, ENTREPRENEURSHIP AND POVERTY ALLEVIATION
Creators: name: Ifeoma Enweani
Publisher: name: figshare
Year: 2020
Subjects: Biotechnology

description: Biotechnology has been defined in various ways depending on the interests and objectives. One broad definition is the application of scientific and engineering principles to modify and/or use biological materials to provide goods and services. This includes any process in which biological agents such as organisms, tissues, cells, organelles, or isolated enzymes are used to convert raw materials to products of greater value or to degrade or remove waste materials from the environment. It also includes the genetic modification of these biological agents (plants, man, other animals and microorganisms) to inculcate certain desired characteristics to increase inefficiency. Biotechnology can be applied in food and agriculture, industry, medicine and environment. Agricultural biotechnology is needed to achieve food security and produce raw materials for the development of the industrial sector. It can be used to increase the crop yields, improve innate characteristics of the seeds and farm animals and where necessary introduce new and desired traits. Biotechnology has made available crops that are resistant to various diseases and pests; that can mature faster and produce higher yields; that are of better nutritional value with longer shelf life; that have improved flavour and colour of the products; bio-fortified food crops; diet foodstuff for diabetic patients; edible vaccines from plant sources. Human activities and natural disasters including climatic changes have led to an increased environmental pollution and challenges. Biotechnology is employed in reduction of environmental pollution through bioremediation and environmentally friendly alternatives such as bio-insecticides, bio-fertilizers, bio-degradable plastics and bio-energy. There has been an impact of biotechnology in healthcare delivery. A number of medicines and vaccines have been developed leading to a better healthcare and healthy population. Several industries have been established which emanated from the development of biotechnology.
Sonnenfleckenzeichnung Nr. 23573.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.02.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
In silico identification of small molecule modulators for disruption of Hsp90–Cdc37 protein–protein interaction interface for cancer therapeutic application
Creators: name: Dike, Prajakta Prakash
name: Bhowmick, Shovonlal
name: Eldesoky, Gaber E.
name: Wabaidur, Saikh M.
name: Patil, Preeti Chunarkar
name: Islam, Md Ataul
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: The protein–protein interactions (PPIs) in the biological systems are important to maintain a number of cellular processes. Several disorders including cancer may be developed due to dysfunction in the assembly of PPI networks. Hence, targeting intracellular PPIs can be considered as a crucial drug target for cancer therapy. Among the enormous and diverse group of cancer-enabling PPIs, the Hsp90–Cdc37 is prominent for cancer therapeutic development. The successful inhibition of Hsp90–Cdc37 PPI interface can be an important therapeutic option for cancer management. In the current study, a set of more than sixty thousand compounds belong to four databases were screened through a multi-steps molecular docking study in Glide against the Hsp90–Cdc37 interaction interface. The Glide-score and Prime-MM-GBSA based binding free energy of DCZ3112, standard Hsp90–Cdc37 inhibitor were found to be −6.96 and −40.46 kcal/mol, respectively. The above two parameters were used as cut-off score to reduce the chemical space from all successfully docked molecules. Furthermore, the in-silico pharmacokinetics parameters, common-feature pharmacophore analyses and the molecular binding interactions were used to wipe out the inactive molecules. Finally, four molecules were found to be important to modulate the Hsp90–Cdc37 interface. The potentiality of the final four molecules was checked through several drug-likeness characteristics. The molecular dynamics (MD) simulation study explained that all four molecules retained inside the interface of Hsp90–Cdc37. The binding free energy of each molecule obtained from the MD simulation trajectory was clearly explained the strong affection towards the Hsp90–Cdc37. Hence, the proposed molecule might be crucial for successful inhibition of the Hsp90–Cdc37 interface. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 23627.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.04.1971, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Chromatin structure of the 5S ribosomal RNA genes and satellites in Xenopus laevis
Creators: name: Young, Dallan Brent
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: The chromatin structure of the 5S rRNA genes and two satellite DNAs in  Xenopus laevis were investigated.  The average nucleosome repeat lengths of these three repeated sequences were found to be the same as the bulk nucleosome repeat length of 192±4 bp in erythrocyte chromatin, although widths of the nucleosome bands were noticeably different for the three DNAs.  The 5S DNA nucleosome bands were much broader than those from bulk chromatin while the 388 bp satellite bands were noticeably sharper.  This may reflect the difference in the variations of nucleosome repeat lengths of the three sequences.  The positions of micrococcal nuclease sensitive regions in the 5S DNA repeats of purified DNA and chromatin from erythrocytes were determined using an indirect end-labeling hybridization technique.  While most of the sites found in purified DNA are present in chromatin, the patters of intensities are strikingly different in the two cases.  In 5S chromatin, three nuclease-sensitive regions are spaced approximately a nucleosome length apart, suggesting that nucleosomes occupy a single regular arrangement on most of the 5S DNA repeats.  Because the preferred locations appear to be reestablished in each repeating unit, despite spacer length heterogeneity, the regular chromatin structure may reflect the presence of a sequence-specific DNA-binding component on inactive 5S rRNA genes.  The arrangements of nucleosomes on 5S DNA and the satellite DNAs were also investigated by studying the availability of restriction enzymes Hind III, Rsa I, Mbo I, and Hae III cleave a fraction of their sites in bulk chromatin producing DNA distributions which indicate that they probably cleave chromatin only in the linker DNA between nucleosome cores.  The 5S DNA fragments produced from these digests, as analyzed by Southern blot hybridization, indicate that only a fraction of the restriction sites in the 5S DNA repeats are available for cleavage in chromatin.  These results are analyzed with respect to the single nucleosome arrangement of 5S DNA repeats deduced from the micrococcal nuclease cleavage map.  Preliminary analyses of the chromatin structure of the 741 bp satellite I do not indicate a phased nucleosome arrangement on this DNA sequence, while the 388 bp repeating sequence may be organized in a regular chromatin structure.  The close relation between the 388 bp sequence repeat length and the nucleosome dimer length suggests that nucleosomes may be phased.  Also, analysis of micrococcal nuclease cleavage of the 388 base pair satellite indicates that the positions of sensitive sties in erythrocyte chromatin and purified DNA are different.
Sonnenfleckenzeichnung Nr. 23578.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.02.1971, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Space based evaluation of the aerosol indirect effect in the Arctic
Creators: name: Tietze, Kyle
Publisher: name: University of Utah
Year: 2012
Subjects: Aerosol
Artic
Space-based
Atmospheric aerosols

description: During the Arctic winter and spring, enhanced levels of aerosol particles and trace gases form a pronounced haze originating primarily from industrial pollutants transported into the region. The haze rapidly dissipates during the late spring as pollution transport is inhibited and meteorological conditions favor pollutant removal. Prior ground based studies have found that aerosols associated with the "Arctic haze" have the potential to indirectly alter Arctic cloud surface radiative forcing in both the solar and thermal IR bands. While satellites have been used extensively to study the indirect effects of aerosols on clouds in lower latitude regions, they rarely are employed in Arctic studies. One limitation of using satellites to study aerosols and clouds is that they do not provide retrievals of aerosol concentrations under cloudy conditions nor do they resolve aerosol vertical profiles; co-location of aerosol and cloud fields is therefore impossible. The ubiquitous nature of Arctic clouds makes the common practice of comparing cloud properties to aerosol in nearby cloud free regions a difficult task in the Arctic, providing little information about aerosol-cloud interactions.  Here, in order to circumvent these concerns, passive satellite cloud property retrievals are co-located horizontally, vertically and temporally with pollution tracers from a Lagrangian particle dispersion transport model. The advantage of this analysis approach is  that clouds and pollution are compared where they are affected by the same meteorological conditions. This means that pollution can be treated as an independent variable affecting cloud properties. Cloud properties from low level liquid clouds north of 65 °N are colocated  with fields of pollution tracer during the period March 20 to July 20, 2008. The analysis shows a high sensitivity of cloud optical depth and droplet effective radius to the anthropogenic and biomass burning pollution tracers. Furthermore, the cloud sensitivity to pollution is evaluated under different thermodynamic and physical constraints. Results of the analysis show a strong indication of wet-scavenging reducing the effects of pollution on clouds at warmer temperatures. Additionally, the sensitivity to pollution is higher for cloud optical depth than for droplet effective radius, suggesting that some sort of feedback process amplifies the radiative response through changes in liquid water path.
Improving the representation of turbulence and clouds in cloud resolving models and general circulation models
Creators: name: Bogenschutz, Peter A.
Publisher: name: University of Utah
Year: 2014
Subjects: Climate models
Clouds
Turbulence

description: Over the past few years a new type of general circulation model (GCM) has emerged that is known as the multiscale modeling framework (MMF). The Colorado State University (CSU) MMF represents a coupling between the Community Atmosphere Model (CAM) GCM and the System of Atmospheric Modeling (SAM) cloud resolving model (CRM). Within this MMF the embedded CRM replaces the traditionally used parameterized moist physics in CAM to represent subgrid-scale (SGS) convection. However, due to substantial increases of computational burden associated with the MMF, the embedded CRM is typically run with a horizontal grid size of 4 km. With a horizontal grid size of 4 km, a low-order closure CRM cannot adequately represent shallow convective processes, such as trade-wind cumulus or stratocumulus. A computationally inexpensive parameterization of turbulence and clouds is presented in this dissertation. An extensive a priori test is performed to determine which functional form of an assumed PDF is best suited for coarse-grid CRMs for both deep shallow and deep convection. The diagnostic approach to determine the input moments needed for the assumed PDFs uses the subgrid-scale (SGS) turbulent kinetic energy (TKE) as the basis for the parameterization. The term known as the turbulent length scale (L) is examined, as it is needed to parameterize the dissipation of turbulence and therefore is needed to better balance the budgets of SGS TKE. A new formulation of this term is added to the model code which appears to be able to partition resolved and SGS TKE fairly accurately. Results from "offline" tests of the simple diagnostic closure within SAM shows that the cloud and turbulence properties of shallow convection can be adequately represented when compared to large eddy simulation (LES) benchmark simulations. Results are greatly improved when compared to the standard version of SAM. The preliminary test of the scheme within the embedded CRM of the MMF shows promising results with the simulation of shallow convection. Overall, this scheme represents a new type of flexible turbulence and cloud parameterization that is computationally efficient.
Pelidnota cerdai
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Pelidnota
Pelidnota cerdai

description: Pelidnota cerdai (Soula, 2006)
Strigidia cerdai Soula 2006: 48 (French Guiana)
Distribution. Suriname: CLVV - NEW COUNTRY RECORD (Suriname.). French Guiana: Soula 2006: 48, 2010a: 55; Moore et al. 2017: 174.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 147, DOI: 10.5281/zenodo.3678492
Panax ginseng ameliorate toxic effects of cadmium on germ cell apoptosis, sperm quality, and oxidative stress in male Wistar rats
Creators: name: Shojaeepour, Saeedeh
name: Sharififar, Fariba
name: Haghpanah, Tahereh
name: Iranpour, Maryam
name: Imani, Masoud
name: Dabiri, Shahriar
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: Panax ginseng is known to potentiate the immune system via its antioxidant properties. Cadmium as an environmental pollutant has destructive effects on body organs especially the reproductive system. This study investigated the effects of P. ginseng extract against cadmium-induced testicular toxicity in rats. In this experimental study, 50 male adult rats were randomly divided into 5 groups: A significant decrease was observed in sperm count and viability in the cadmium group versus the control group. Ginseng extract could repair these defects. Increases in apoptotic germ cells due to cadmium were significantly reduced by ginseng extract. Our results demonstrated that P. ginseng extract reduces cadmium-induced testicular toxicity, via anti-oxidative and anti-apoptotic processes.
Sonnenfleckenzeichnung Nr. 23599.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.03.1971, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Structural investigations of metabolites from four marine invertebrates
Creators: name: Mitchell, Scott S.
Publisher: name: University of Utah
Year: 2012
Subjects: Ascidian Didemnum Voeltzkowi
Conotoxin
Amphimedon Viridis

description: Each of the projects described in this thesis entails either the three-dimensional or covalent structure determination of metabolites from marine invertebrates.  The first chapter reviews literature reports of three-dimensional structures of conotoxins.  As more structural work in completed for contoxins, additional biological insights are revealed about the binding sites for each of the toxins.  A section summarizing the biological implications of the three-dimensional contoxin structures has been included for each pharmacological class of peptides.  The second chapter discusses the solution NMR structure of the recently described conotoxin known as psi-PIIIE.  Though this peptide contains the same disulfide bonding framework as the µ-conotoxins, its biological activity is unique as it targets the acetylcholine gated ion channel rather than the voltage gated sodium channel.  Furthermore, inhibition of the acetylcholine gated ion channel by  psi-PIIIE occurs by a different mechanism than the psi-conotoxins, demonstrating that the psi-conotoxin represent a novel pharmacological class of conotoxins.  Determination of the three-dimensional structure of psi-PIIIE represents an important initial step in understanding what structural components of the peptides are required for this unique activity.  Chapter 3 and 4 describe the isolation and structure determination of several nucleic acid derivatives from the ascidian Didemnum voeltzkowi and the sponge Amphimedon viridis.  The covalent structure of nucleic acids is difficult to determine using only NMR spectroscopy, and mass spectroscopic and synthetic techniques were also employed in the complete structure determination of these metabolites.  Chapter 5 discusses the isolation of a novel blue pigment from the ascidian Eudistoma olivaceum and includes evidence supporting a structural proposal for the metabolite.  Purification of the compound required extensive investigations of the solubility and stability of the compound, which in turn yielded several important clues to the structure of the molecule.  The results of chemical degradation experiments on the natural product and numerous spectroscopic techniques are also described, providing considerable evidence for the proposed structure.
Sonnenfleckenzeichnung Nr. 23543.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.01.1971, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1971

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel