Additional file 1 of Prevention of cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis of non-pharmacological interventions
Creators: name: Hariri, Geoffroy
name: Collet, Lucie
name: Duarte, Lucie
name: Martin, Guillaume L.
name: Resche-Rigon, Matthieu
name: Lebreton, Guillaume
name: Bouglé, Adrien
name: Dechartres, Agnès
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: eTable 1. Changes between the protocol and the article in the Outcome and the Data Analysis. Supplemental eMaterial 1. Search algorithm in PubMed. eTable2. Detailed characteristics of each included trial by intervention. eTable3. Characteristics of chronic kidney disease population for each intervention. eFigure 1. Risk of bias of randomized controlled trials assessing a non-pharmacological intervention to prevent cardiac surgery associated - acute kidney injury. eFigure 2a. Definition of cardiac surgery associated acute kidney injury in all included RCTs according to each intervention. eFigure 2b. Acute kidney injury definition according to the year of publication of the trials. eFigure 3. Meta-analysis of the effect of goal directed perfusion (GDP) on cardiac surgery associated acute kidney injury. eFigure 4. Subgroup analysis of the effect of Remote ischemic preconditioning (RIPc) on cardiac surgery associated acute kidney injury according the Risk of bias. eFigure 5. Subgroup analysis of the effect of Remote ischemic preconditioning (RIPc) on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 6. Subgroup analysis of the effect of Remote ischemic preconditioning (RIPc) on cardiac surgery associated acute kidney injury according the type of surgery. eFigure 7. Funnel plot for random effects meta-analysis of cardiac surgery associated acute kidney injury outcomes in trials of Remote ischemic preconditioning. eFigure 8. Meta-analysis of the effect of pulsatile flow on cardiac surgery associated acute kidney injury. eFigure 9. Subgroup analysis of the effect of pulsatile flow on cardiac surgery associated acute kidney injury according the modality of pulsatility. eFigure 10. Subgroup analysis of the effect of pulsatile flow on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 11. Subgroup analysis of the effect of pulsatile flow on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 12. Funnel plot for random effects meta-analysis of CSA-AKI outcomes in RCTs of Pulsatile flow during CPB. eFigure 13. Meta-analysis of the effect of Minimally invasive extracorporeal circulation (MECC) on cardiac surgery associated acute kidney injury. eFigure 14. Subgroup analysis of the effect of Minimally invasive extracorporeal circulation (MECC) on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 15. Subgroup analysis of the effect of Minimally invasive extracorporeal circulation (MECC) on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 16. Subgroup analysis of the effect of Minimally invasive extracorporeal circulation (MECC) on cardiac surgery associated acute kidney injury according the type of surgery. eFigure 17. Funnel plot for random effects meta-analysis of cardiac surgery associated acute kidney injury outcomes in trials of Minimally invasive extracorporeal circulation (MECC). eFigure 18. Meta-analysis of the effect of restrictive transfusion strategy on cardiac surgery associated acute kidney injury. eFigure 19. Subgroup analysis of the effect of restrictive transfusion strategy on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 20. Subgroup analysis of the effect of restrictive transfusion strategy on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 21. Meta-analysis of the effect of tight glycemic (BG) control on cardiac surgery associated acute kidney injury. eFigure 22. Subgroup analysis of the effect of tight glycemic (BG) control on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 23. Subgroup analysis of the effect of tight glycemic (BG) control on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 24. Funnel plot of tight glycemic control on cardiac surgery associated acute kidney injury. eFigure 25. Meta-analysis of the effect of Epidural analgesia on cardiac surgery associated acute kidney injury. eFigure 26. Subgroup analysis of the effect of Epidural analgesia on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 27. Subgroup analysis of the effect of Epidural analgesia on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 28. Meta-analysis of the effect of KDIGO bundle of care on cardiac surgery associated acute kidney injury. eFigure 29. Subgroup analysis of the effect of KDIGO care on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 30. Meta-analysis of the effect of high-target arterial pressure (MAP) target on cardiac surgery associated acute kidney injury. eFigure 31. Subgroup analysis of the effect of high-target arterial pressure (MAP) target on cardiac surgery associated acute kidney injury according the definition of acute kidney injury (AKI). eFigure 32. Meta-analysis of the effect of hyperoxia on cardiac surgery associated acute kidney injury. eFigure 33. Subgroup analysis of the effect of hyperoxia on cardiac surgery associated acute kidney injury according the risk of bias. eFigure 34. Forest plot of non-pharmacological interventions for efficacy in reducing risk of mortality. Interventions were tested with standard medical care as control. eFigure 35. Forest plot of non-pharmacological interventions for efficacy in reducing risk of RRT. Interventions were tested with standard medical care as control. eFigure 36. Forest plot of non-pharmacological interventions for efficacy in reducing lenght of hospital stay. Interventions were tested with standard medical care as control. eFigure 37. Forest plot of non-pharmacological interventions for efficacy in reducing length of Intensive care unit stay. Interventions were tested with standard medical care as control. eFigure 38. Forest plot of non-pharmacological interventions for efficacy in reducing risk of post-operative stroke. Interventions were tested with standard medical care as control. eFigure 39. Forest plot of non-pharmacological interventions for efficacy in reducing risk of post-operative myocardial infarction. Interventions were tested with standard medical care as control. eFigure 40. Forest plot of non-pharmacological interventions for efficacy in reducing risk of post-operative atrial fibrillation. Interventions were tested with standard medical care as control. eTable 4. Summary of quality of evidence for the effect of each intervention on CSA-AKI according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).