cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Breast contrast enhanced MR imaging: semi-automatic detection of vascular map
Creators: name: Fusco, Roberta
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Breast
subject: MR
subject: Segmentation
subject: Neoplasia

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: MRI is one of the most accurate methods for detection of invasive breast cancer, having nearly 100% sensitivity [1]. The specificity, however, is only moderate (72% overall specificity in 44 studies [1]) and varies widely across studies of the...
'CFTR-opathies': disease phenotypes associated with cystic fibrosis transmembrane regulator gene mutations
Creators: name: Knowles, Michael
name: Noone, Peadar G
Publisher: name: BioMed Central Ltd
Year: 2001

description: Abstract Cystic fibrosis is a genetic disease that is associated with abnormal sweat electrolytes, sino-pulmonary disease, exocrine pancreatic insufficiency, and male infertility. Insights into genotype/phenotype relations have recently been gained in this disorder. The strongest relationship exists between 'severe' mutations in the gene that encodes the cystic fibrosis transmembrane regulator (CFTR) and pancreatic insufficiency. The relationship between 'mild' mutations, associated with residual CFTR function, and expression of disease is less precise. Atypical 'mild' mutations in the CFTR gene have been linked to late-onset pulmonary disease, congenital bilateral absence of the vas deferens, and idiopathic pancreatitis. Less commonly, sinusitis, allergic bronchopulmonary aspergillosis, and possibly even asthma may also be associated with mutations in the CFTR gene, but those syndromes predominantly reflect non-CFTR gene modifiers and environmental influences.
Augmenting Agent Platforms to Facilitate Conversation Reasoning
Creators: name: Lillis, David
name: Collier`, Rem W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: Within Multi Agent Systems, communication by means of Agent Communication Languages (ACLs) has a key role to play in the co-operation, co-ordination and knowledge-sharing between agents. Despite this, complex reasoning about agent messaging, and specifically about conversations between agents, tends not to have widespread support amongst general-purpose agent programming languages. ACRE (Agent Communication Reasoning Engine) aims to complement the existing logical reasoning capabilities of agent programming languages with the capability of reasoning about complex interaction protocols in order to facilitate conversations between agents. This paper outlines the aims of the ACRE project and gives details of the functioning of a prototype implementation within the Agent Factory multi agent framework.
title: Contrast enhanced MR Imaging breast vascular maps: automatic detection and correlation of predominant feeding vessel and cancer location
Creators: name: Fusco, Roberta
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Breast
subject: Pelvis
subject: Colon
subject: CAD
subject: MR
subject: MR-Functional imaging
subject: CAD
subject: Computer Applications-Detection, diagnosis
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Magnetic resonance imaging (MRI) has become an important imaging modality in the diagnostic workup of breast cancer patients. MRI is the most accurate method for invasive breast cancer detection, having nearly 100% sensitivity [1]. The...
title: Modified percutaneous radiologic gastrostomy technique without endoscopic or nasogastric access
Creators: name: Tabashy, Reda
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Interventional non-vascular
subject: Ultrasound
subject: Fluoroscopy
subject: Technical aspects

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Gastrostomy is required to provide enteral nutrition to dysphagic patients with esophageal and neck cancers during combined chemotherapy and radiotherapy treatment due to an obstructed upper digestive tract [1]. Percutaneous endoscopic gastrostomy...
title: Whole-Body MRI of Indeterminate Pulmonary Nodules
Creators: name: Bristogiannis, Christos
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Neoplasia
subject: Image verification
subject: Technology assessment
subject: Imaging sequences
subject: Experimental investigations
subject: MR-Diffusion/Perfusion
subject: MR
subject: Lung

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Currently CT represents the gold standard for morphological, dimensional, topographicaland structural pulmonary nodule evaluation, indeed it's the most used non invasivemethod for pulmonary neoplasm staging. MRI is rarely used for the evaluation of...
title: Fetal Facial Clefts - A Review of Imaging Appearances in Fetal MRI.
Creators: name: Lo, Adeline
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Foetus
subject: Congenital
subject: Education
subject: MR
subject: Head and neck
subject: Foetal imaging
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Orofacial clefts are one of the most common congenital craniofacial anomalies affecting about 1/700 live births. Causes of these malformations, which occur early in gestation, are likely multifactorial, with links to environmental factors such as...
title: Parameter optimization for 4D imaging for the development of real-time reference-less MR temperature mapping
Creators: name: Karakitsios, Ioannis
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Liver
subject: MR
subject: Technology assessment
subject: Image guided radiotherapy

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Normal 0 false false false EN-GB ZH-CN X-NONE Reference-less thermometry is a useful tool in real time liver tumour ablation with MR-guided Focused Ultrasound (MRgFUS) (1). However, this method requires improvement of the resolution and optimisation...
title: The diaphragm: Imaging of the anatomy and pathology
Creators: name: Cartón Sánchez, Pilar
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Education and training
subject: Diagnostic procedure
subject: Ultrasound
subject: CT
subject: Conventional radiography
subject: Thorax
subject: Anatomy
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Reviewing the anatomic characteristics of the diaphragm and analyzing the different diseases that affect it. Showing the different image techniques which are useful for the correct assessment of the diaphragmatic pathology and the instructions of...
title: Dating and Rating Landscape Evolution with Geochemical Methods on Geomorphic to Geologic Time Scales
Creators: name:  Madella , Andrea
name: Falkowski , Sarah
name: Eizenhöfer , Paul R.
name: Glotzbach , Cristoph
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: The Earth's surface is under constant change. Tectonic, climatic, biogenic and anthropogenic forcings have a measurable impact on erosion, weathering and surface uplift. Information on the interactions among these processes and their spatio-temporal distribution can be inferred from observations of the available geologic archives. These involve, among others, the morphology and the geochemical-mineralogical composition of exposed bedrock, sedimentary products and soils. In order to successfully predict future landscape responses, it is therefore important to investigate these archives and to quantify the timing and rate of past landscape changes in response to the different forcings. In this session, we gather contributions involving state-of-the-art applications of geochronologic, thermochronologic and geochemical methods, aiming to quantify dates and rates of landscape change. In particular, we welcome any field-, laboratory- and/or modeling-based study, covering a range of timescales (hundreds to millions years), spatial scales (hillslope, catchment, orogen) and techniques (e.g. cosmogenic nuclides, thermochronology, luminescence, isotopic dating etc...).
title: Initial Experience with 3D Isotropic High-Resolution 3T MR Arthrography of the Wrist
Creators: name: Sutherland, John
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Athletic injuries
subject: Arthrography
subject: MR
subject: Musculoskeletal joint

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The wrist, given its relative small size compared to other joints and complex arrangement of ligaments, requires high-resolution, high signal-to-noise, and small field of view MR imaging for accurate assessment of anatomy and pathology. When...
title: The clinical significance of common radiographic parameters of intraarticular calcaneal fractures in terms of pain duration after non-operative management
Creators: name: Chan, Samuel
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Musculoskeletal bone
subject: Digital radiography
subject: Outcomes analysis
subject: Trauma

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Introduction: The os calcis is the most commonly fractured tarsal bone of the foot and around three quarters of them are intra-articular fractures. The management of calcaneal fractures, conservative or operative, is controversial as the evidence...
Asymmetric interference in serial memory tasks
Creators: name: Morey, Candice
name: Miron, Monica
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: dual-task interference
subject: memory
subject: serial memory
subject: serial order reconstruction
subject: short-term memory
subject: spatial memory
subject: verbal memory
subject: working memory

description: Although there are many instances showing that verbal memories interfere with visual memories (see C. Morey, R. Morey, van der Reijden, & Holweg, 2013), in many tasks verbal memories do not suffer at all during a concurrent visual task. With this project, we examine this using serial reconstruction tasks.
title: Sono-mammographic findings of Mondor`s disease of the breast
Creators: name: Moustafa, Amr
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Pathology
subject: Diagnostic procedure
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Mammography
subject: Vascular
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Mondor’s disease or superficial thrombophlebitis of the breast is a rare benign breast entity, may be due to lack of awareness of it. An understanding of the epidemiology, pathogenesis, clinical presentation and the sono-mammographic imaging...
Estimate of the theoretical uncertainty of the cross sections for nucleon knockout in neutral-current neutrino-oxygen interactions
Creators: name: Ankowski, Artur M.
name: Barbaro, Maria B.
name: Benhar, Omar
name: Caballero, Juan A.
name: Giusti, Carlotta
name: González-Jiménez, Raúl
name: Megias, Guillermo D.
name: Meucci, Andrea
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Free nucleons propagating in water are known to produce gamma rays, which form a background to the searches for diffuse supernova neutrinos and sterile neutrinos carried out with Cherenkov detectors. As a consequence, the process of nucleon knockout induced by neutral-current quasielastic interactions of atmospheric (anti)neutrinos with oxygen needs to be under control at the quantitative level in the background simulations of the ongoing and future experiments. In this paper, we provide a quantitative assessment of the uncertainty associated with the theoretical description of the nuclear cross sections, estimating it from the discrepancies between the predictions of different models.
description: 7 pages, 2 figures
Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay
Creators: name: Hu, Zhiyuan
name: Perou, Charles
name: He, Xiaping
name: Fan, Cheng
Publisher: name: BioMed Central Ltd
Year: 2006

description: Abstract: Introduction: Predicting the clinical course of breast cancer is often difficult because it is a diverse disease comprised of many biological subtypes. Gene expression profiling by microarray analysis has identified breast cancer signatures that are important for prognosis and treatment. In the current article, we use microarray analysis and a real-time quantitative reverse-transcription (qRT)-PCR assay to risk-stratify breast cancers based on biological 'intrinsic' subtypes and proliferation. Methods: Gene sets were selected from microarray data to assess proliferation and to classify breast cancers into four different molecular subtypes, designated Luminal, Normal-like, HER2+/ER-, and Basal-like. One-hundred and twenty-three breast samples (117 invasive carcinomas, one fibroadenoma and five normal tissues) and three breast cancer cell lines were prospectively analyzed using a microarray (Agilent) and a qRTPCR assay comprised of 53 genes. Biological subtypes were assigned from the microarray and qRT-PCR data by hierarchical clustering. A proliferation signature was used as a single metagene (log2 average of 14 genes) to predict outcome within the context of estrogen receptor status and biological 'intrinsic' subtype. Results: We found that the qRT-PCR assay could determine the intrinsic subtype (93% concordance with microarray-based assignments) and that the intrinsic subtypes were predictive of outcome. The proliferation meta-gene provided additional prognostic information for patients with the Luminal subtype (P = 0.0012), and for patients with estrogen receptor-positive tumors (P = 3.4 × 10-6). High proliferation in the Luminal subtype conferred a 19-fold relative risk of relapse (confidence interval = 95%) compared with Luminal tumors with low proliferation. Conclusion: A real-time qRT-PCR assay can recapitulate microarray classifications of breast cancer and can risk-stratify patients using the intrinsic subtype and proliferation. The proliferation meta-gene offers an objective and quantitative measurement for grade and adds significant prognostic information to the biological subtypes.
Sensitivity of the Self-Report Symptom Inventory to instructed over-reporting
Creators: name: Boskovic, Irena
name: Merckelbach, Harald
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: malingering
subject: over-reporting
subject: SRSI

description: The Self-Report Symptom Inventory (SRSI; Merten et al., 2016) is a newly developed questionnaire that intends to detect over-reporting of symptoms in the context of e.g. litigation (e.g., subjects who seek compensation for traumatic brain injury, chronic fatigue, PTSD). A preliminary report concluded that the psychometric properties of the SRSI are promising, but much work needs to be done. This study wants to contribute to normative data about the SRSI. Basically, the SRSI consists of two types of items. One type is tapping into plausible complaints (e.g., I am rarely in a good mood; I am often exhausted) and the other is tapping into rare symptoms (e.g., Sometimes my left leg is really weak, sometimes the right one is; When I am in extreme pain I get double vision). The rationale is that patients will endorse more plausible than rare symptoms, while this differential pattern is absent in people who over-report/simulate their complaints. We want to test whether 1) differential responding is also present in a student comparison group (if students would endorse as much rare symptoms as real symptoms that would cast doubts on the quality of the SRSI) and 2) the SRSI can detect over-reporting when students are instructed to fake anxiety-symptoms, pain symptoms or fatigue.
Droplet migration in a Hele-Shaw cell: Effect of the lubrication film on the droplet dynamics
Creators: name: Ling, Yue
name: Fullana, Jose-Maria
name: Popinet, Stéphane
name: Josserand, Christophe
Publisher: name: arXiv
Year: 2016
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Droplet migration in a Hele--Shaw cell is a fundamental multiphase flow problem which is crucial for many microfluidics applications. We focus on the regime at low capillary number and three-dimensional direct numerical simulations are performed to investigate the problem. In order to reduce the computational cost, an adaptive mesh is employed and high mesh resolution is only used near the interface. Parametric studies are performed on the droplet horizontal radius and the capillary number. For droplets with an horizontal radius larger than half the channel height the droplet overfills the channel and exhibits a pancake shape. A lubrication film is formed between the droplet and the wall and particular attention is paid to the effect of the lubrication film on the droplet velocity. The computed velocity of the pancake droplet is shown to be lower than the average inflow velocity, which is in agreement with experimental measurements. The numerical results show that both the strong shear induced by the lubrication film and the three-dimensional flow structure contribute to the low mobility of the droplet. In this low-migration-velocity scenario the interfacial flow in the droplet reference frame moves toward the rear on the top and reverses direction moving to the front from the two side edges. The velocity of the pancake droplet and the thickness of the lubrication film are observed to decrease with capillary number. The droplet velocity and its dependence on capillary number cannot be captured by the classic Hele--Shaw equations, since the depth-averaged approximation neglects the effect of the lubrication film.
title: Role of sono-mammography in the evaluation of clinically palapble breast masses during pregnancy & lactation with differentaition between true patholgical & false physiological lobular hyperlpasia.Sudanese experience.
Creators: name: Moustafa, Amr
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Biological effects
subject: Diagnostic procedure
subject: Ultrasound
subject: Mammography
subject: Breast

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: During pregnancy and lactation the breasts undergoes significant changes in the breast parenchyma representing unique physiologic states. Considerable hypertrophy of the ductal-lobular-alveolar system occurs. These physiologic changes start at...
title: Poorman's colonic phantom - construction and validation
Creators: name: Lambert, Lukas
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Abdomen
subject: Colon
subject: CT
subject: CAD
subject: Colonography CT
subject: Equipment

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The purpose of this study was to construct a colonic phantom with multiple intermediate to large polyps of soft tissue density for subsequent testing of various preparation protocols and different scanner...
Health behavior change in advance care planning: an agent-based model
Creators: name: Ernecoff, Natalie C
Publisher: name: BioMed Central
Year: 2016

description: Abstract Background A practical and ethical challenge in advance care planning research is controlling and intervening on human behavior. Additionally, observing dynamic changes in advance care planning (ACP) behavior proves difficult, though tracking changes over time is important for intervention development. Agent-based modeling (ABM) allows researchers to integrate complex behavioral data about advance care planning behaviors and thought processes into a controlled environment that is more easily alterable and observable. Literature to date has not addressed how best to motivate individuals, increase facilitators and reduce barriers associated with ACP. We aimed to build an ABM that applies the Transtheoretical Model of behavior change to ACP as a health behavior and accurately reflects: 1) the rates at which individuals complete the process, 2) how individuals respond to barriers, facilitators, and behavioral variables, and 3) the interactions between these variables. Methods We developed a dynamic ABM of the ACP decision making process based on the stages of change posited by the Transtheoretical Model. We integrated barriers, facilitators, and other behavioral variables that agents encounter as they move through the process. Results We successfully incorporated ACP barriers, facilitators, and other behavioral variables into our ABM, forming a plausible representation of ACP behavior and decision-making. The resulting distributions across the stages of change replicated those found in the literature, with approximately half of participants in the action-maintenance stage in both the model and the literature. Conclusions Our ABM is a useful method for representing dynamic social and experiential influences on the ACP decision making process. This model suggests structural interventions, e.g. increasing access to ACP materials in primary care clinics, in addition to improved methods of data collection for behavioral studies, e.g. incorporating longitudinal data to capture behavioral dynamics.
title: Unenhanced CT of thorax: comparison of radiation dose and image quality among three CT scanners in a single institution
Creators: name: Lambert, Lukas
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Thorax
subject: Radioprotection / Radiation dose
subject: CT
subject: Diagnostic procedure

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The purpose of this study was to compare radiation dose and image quality of unenhanced CT of thorax among three CT scanners in a single...
title: Congenital Dolichoectasia of Cerebral Arteries
Creators: name: Gök, Mustafa
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Interventional vascular
subject: CNS
subject: Anatomy
subject: Catheter arteriography
subject: CT-Angiography
subject: MR-Angiography
subject: Normal variants
subject: Screening
subject: Congenital
subject: Epidemiology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Definition of Dolichoectasia Types of Dolichoectasia Theories for etiologic mechanism Clinical presentations of Congenital Dolichoectasia patients Possible management options of these...
title: Diffusion-weighted MR imaging for Diagnosis of Uterine Leiomyomas
Creators: name: Gök, Mustafa
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Genital / Reproductive system female
subject: MR physics
subject: MR-Diffusion/Perfusion
subject: MR
subject: Imaging sequences
subject: Molecular imaging
subject: Outcomes analysis
subject: Image verification
subject: Pathology
subject: Tissue characterisation

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Uterine leiomyomas or fibroids are the most common pelvic tumors in women. The insidence of these tumors is 30%, in women over age 30 (1). As high resolution Magnetic Resonance equipment were introduced and commonly used, Magnetic Resonance Imaging...
title: Clinical Experience with Foot and Ankle SPECT/CT:- From Dark horse to Fore runner of Foot and Ankle Imaging
Creators: name: Low, Kai En
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Trauma
subject: Education
subject: SPECT-CT
subject: Extremities
subject: Bones

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Describe the protocol for Tc-99m HDP SPECT-CT. 2. Case review of pathology identified on Tc-99m HDP SPECT-CT. 3. Follow-up of HDP SPECT-CT with subsequent MR and comparison of clinical utility of MR. 4. Review of clinical management of patient...
High-speed imaging and wavefront sensing with an infrared avalanche photodiode array
Creators: name: Baranec, Christoph
name: Atkinson, Dani
name: Riddle, Reed
name: Hall, Donald
name: Jacobson, Shane
name: Law, Nicholas M.
name: Chun, Mark
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Infrared avalanche photodiode arrays represent a panacea for many branches of astronomy by enabling extremely low-noise, high-speed and even photon-counting measurements at near-infrared wavelengths. We recently demonstrated the use of an early engineering-grade infrared avalanche photodiode array that achieves a correlated double sampling read noise of 0.73 e- in the lab, and a total noise of 2.52 e- on sky, and supports simultaneous high-speed imaging and tip-tilt wavefront sensing with the Robo-AO visible-light laser adaptive optics system at the Palomar Observatory 1.5-m telescope. We report here on the improved image quality achieved simultaneously at visible and infrared wavelengths by using the array as part of an image stabilization control-loop with adaptive-optics sharpened guide stars. We also discuss a newly enabled survey of nearby late M-dwarf multiplicity as well as future uses of this technology in other adaptive optics and high-contrast imaging applications.
description: Accepted to Astrophysical Journal. 8 pages, 3 figures and 1 table
A window into living with an undiagnosed disease: illness narratives from the Undiagnosed Diseases Network
Creators: name: Hooper, Stephen R.
Publisher: name: BioMed Central
Year: 2017

description: Abstract Background Patients’ stories of their illnesses help bridge the divide between patients and providers, facilitating more humane medical care. Illness narratives have been classified into three types: restitution (expectation of recovery), chaos (suffering and loss), and quest (unexpected positive effect from illness). Undiagnosed patients have unique illness experiences and obtaining their narratives would provide insights into the medical and emotional impact of living with an undiagnosed illness. Adults and children with undiagnosed diseases apply to be evaluated by the Undiagnosed Diseases Network (UDN). Written illness narratives from 40 UDN applicants, including 20 adult probands who applied for themselves and 20 parents who applied for their children, were analyzed for: 1) narrative content and 2) narrative type. Results Narrative content: could be grouped into three themes: 1) Expectations of the UDN: the majority felt they had no further healthcare options and hoped the UDN would provide them with a diagnosis, with the adults expecting to return to their previously healthy life and the parents wanting information to manage their child’s healthcare. 2) Personal medical information: the narratives reported worsening of symptoms and some offered opinions regarding the cause of their illness. The proband narratives had few objective findings, while parental narratives had detailed objective information. 3) Experiences related to living with their undiagnosed illness: frustration at being undiagnosed was expressed. The adults felt they had to provide validation of their symptoms to providers, given the lack of objective findings. The parents worried that something relevant to their child’s management was being overlooked. Narrative type: All the narratives were of the chaos type, but for different reasons, with the probands describing loss and suffering and the parents expressing fear for their child’s future. The parental narratives also had elements of restitution and quest, with acceptance of “a new normal”, and an emphasis on the positive aspects of their child’s illness which was absent from the probands. Conclusions These narratives illustrate the chaos that coexists with being undiagnosed. The differences between the proband and parental narratives suggest that these two groups have different needs that need to be considered during their evaluation and management.
Anomalous energetics and dynamics of moving vortices
Creators: name: Radzihovsky, Leo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Motivated by the general problem of moving topological defects in an otherwise ordered state and specifically, by the anomalous dynamics observed in vortex-antivortex annihilation and coarsening experiments in freely-suspended smectic-C films by Clark, et al., I study the deformation, energetics and dynamics of moving vortices in an overdamped xy-model and show that their properties are significantly and qualitatively modified by the motion.
description: 4 pages, 4 figures
title: Carpal Tunnel Syndrome:Factors affecting clinical outcomes using ultrasound guided & palpation guided injections in Suez Canal zone, Egypt
Creators: name: Sobieh , AHMED
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Treatment effects
subject: Ultrasound-Colour Doppler
subject: Neuroradiology peripheral nerve
subject: Outcomes

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Aim :Exploitating various factors that affect clinical outcomes of ultrasound guidance and palpation guidance for injecting patients suffering from carpal tunnel syndrome in Suez Canal zone ,Egypt. Objectives: To introduce a new therapeutic method...
On the possibility to use semiconductive hybrid pixel detectors for study of radiation belt of the Earth
Creators: name: Guskov, A.
name: Shelkov, G.
name: Smolyanskiy, P.
name: Zhemchugov, A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The scientific apparatus "Gamma-400" designed for study of hadron and electromagnetic components of cosmic rays will be launched to an elliptic orbit with the apogee of about 300 000 km and the perigee of about 500 km. Such a configuration of the orbit allows it to cross periodically the radiation belt and the outer part of magnetosphere. We discuss the possibility to use hybrid pixel detecters based on the Timepix chip and semiconductive sensors on board the "Gamma-400" apparatus. Due to high granularity of the sensor (pixel size is 55 $mu$m) and possibility to measure independently an energy deposition in each pixel, such compact and lightweight detector could be a unique instrument for study of spatial, energy and time structure of electron and proton components of the radiation belt.
description: Proceedings of the ICPPA-2015 conference
Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study
Creators: name: Taylor, Steve
name: Meshnick, Steven R.
Publisher: name: BioMed Central Ltd
Year: 2014

description: Abstract Background Intermittent Preventive Treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) is widely used for the control of malaria in pregnancy in Africa. The emergence of resistance to SP is a concern requiring monitoring the effectiveness of SP for IPTp. Methods This was an in-vivo efficacy study to determine the parasitological treatment response and the duration of post-treatment prophylaxis among asymptomatic pregnant women receiving SP as part of IPTp in Mali and Burkina-Faso. The primary outcome was the PCR-unadjusted % of patients with parasites recurrence by day 42 defined as a positive diagnostic test by malaria smear at any visit between days 4 and 42. Treatment failure was based on the standard World Health Organization criteria. The therapeutic response was estimated using the Kaplan-Meier curve. Results A total of 580 women were enrolled in Mali (N=268) and Burkina-Faso (N=312) and followed weekly for 42 days. Among these, 94.3% completed the follow-up. The PCR-unadjusted cumulative risk of recurrence by day 42 was 4.9% overall, and 3.2% and 6.5% in Mali and Burkina Faso respectively (Hazard Ratio [HR] =2.14, 95%, CI [0.93-4.90]; P=0.070), and higher among the primi– and secundigravida (6.4%) than multigravida (2.2%, HR=3.01 [1.04-8.69]; P=0.042). The PCR-adjusted failure risk was 1.1% overall (Mali 0.8%, Burkina-Faso 1.4%). The frequencies (95% CI) of the dhfr double and triple mutant and dhps 437 and 540 alleles mutant genotype at enrolment were 24.2% (23.7-25.0), 4.7% (4.4-5.0), and 21.4% (20.8-22.0) and 0.37% (0.29-0.44) in Mali, and 7.1% (6.5-7.7), 44.9% (43.8-46.0) and 75.3% (74.5-76.2) and 0% in Burkina-Faso, respectively. There were no dhfr 164L or dhps 581G mutations. Conclusion SP remains effective at clearing existing infections when provided as IPTp to asymptomatic pregnant women in Mali and Burkina. Continued monitoring of IPTp-SP effectiveness, including of the impact on birth parameters in this region is essential.
title: The added value of SPECT/CT in dacryoscintigraphy for the diagnosis of nasolacrimal duct obstruction
Creators: name: Law, Martin
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Education and training
subject: Instrumentation
subject: SPECT-CT
subject: Nuclear medicine conventional
subject: Radiation physics
subject: Nuclear medicine
subject: Eyes

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Epiphora, an abnormal overflow of tears, is commonly caused by tear drainage system anomalies including nasolacrimal duct obstruction. To evaluate the function of the system, dacryoscintigraphy is a commonly available non-invasive method under a...
A 750 GeV Portal: LHC Phenomenology and Dark Matter Candidates
Creators: name: D'Eramo, Francesco
name: de Vries, Jordy
name: Panci, Paolo
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We study the effective field theory obtained by extending the Standard Model field content with two singlets: a 750 GeV (pseudo-)scalar and a stable fermion. Accounting for collider productions initiated by both gluon and photon fusion, we investigate where the theory is consistent with both the LHC diphoton excess and bounds from Run 1. We analyze dark matter phenomenology in such regions, including relic density constraints as well as collider, direct, and indirect bounds. Scalar portal dark matter models are very close to limits from direct detection and mono-jet searches if gluon fusion dominates, and not constrained at all otherwise. Pseudo-scalar models are challenged by photon line limits and mono-jet searches in most of the parameter space.
description: 25 pages + appendices, 8+1 figures. v2: relic density computation and mono-jet analysis improved; some clarifications and references added; conclusions unchanged. v3: version published in JHEP
17beta-estradiol suppresses TLR3-induced cytokine and chemokine production in endometrial epithelial cells
Creators: name: Young, Steven
Publisher: name: BioMed Central Ltd
Year: 2005

description: Abstract Background The human endometrium is an important site for contact between the host and pathogens ascending the reproductive tract, and thus plays an important role in female reproductive tract immunity. Previous work in our laboratory has suggested that Toll-like receptors (TLRs) are involved in endometrial epithelial recognition of pathogens and that ligation of endometrial TLRs results in the production of cytokines and chemokines important for both immune and reproductive functions of the endometrium. We have also demonstrated cyclic regulation of TLR3 mRNA and protein expression in human endometrium, suggesting that steroid hormones might play a role in the expression and function of TLR3. In this study, the effects of 17beta-estradiol (E2) and progesterone (P) on TLR3 expression and function in endometrial cell lines were investigated. Methods Endometrial epithelial cell lines were cultured and examined for the presence of TLR3 and hormone receptors by endpoint RT-PCR. For hormonal studies, cells were pre-treated with ethanol vehicle, 10^(-8) M E2, and/or 10^(-7) M P. For antagonist assays, cells were treated with the ER antagonist, ICI 182, 780, or the PR antagonist, RU486, for two hours prior to treatment with hormones. Following hormone or hormone/antagonist pre-treatment, cells were stimulated with vehicle, the synthetic TLR3 ligand, polyinosinic-polycytidylic acid (Poly I:C), a negative dsDNA control, or a positive control. Cytokine and chemokine production post-stimulation was measured by ELISA. The effects of E2 and P on TLR3 mRNA and protein expression were measured using Real Time RT-PCR and FACS analysis, respectively. Results Stimulation of TLR3-expressing cells with the synthetic TLR3 ligand, Poly I:C, resulted in the production of cytokines and chemokines important for endometrial function and regulation. Suppression of Poly I:C-induced cytokine and chemokine production by cells treated with 10^(-8) M E2, but not cells treated with 10^(-7) M P, was observed in endometrial epithelial cell lines expressing TLR3 and estrogen receptor alpha (ERalpha). The effects of E2 were not observed on cells which did not express ERalpha or in cells pre-treated with the ER antagonist, ICI 182, 780. Treatment with E2 did not affect TLR3 mRNA or protein expression. However, treatment with E2 did suppress cytokine and chemokine production resulting from TLR3 stimulation with Poly I:C, suggesting that E2 modulates TLR3 function. Conclusion The data presented in this study are the first indication that E2 can markedly alter the innate immune response to dsRNA, providing a previously unreported process by which E2 can alter immune responses.
title: Prospective study of comparison between two different second-look ultrasound examinations: hand-held ultrasound (HHUS) and automated breast volume scanner (ABVS)
Creators: name: Kim, Yoonsoo
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Breast
subject: Ultrasound
subject: Diagnostic procedure

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: This study aimed to make assessment the effects of the second-look ultrasound on the determination of surgical procedures accordingly and its usefulness, and to compare the hand held ultrasound (HHUS) and automated breast volume scanner (ABVS) as...
Thousands of Positive Reviews: Distributed Mentoring in Online Fan Communities
Creators: name: Campbell, Julie Ann
name: Aragon, Cecilia
name: Davis, Katie
name: Evans, Sarah
name: Evans, Abigail
name: Randall, David P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Computers and Society (cs.CY)
subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences
subject: H.5.3

description: Young people worldwide are participating in ever-increasing numbers in online fan communities. Far from mere shallow repositories of pop culture, these sites are accumulating significant evidence that sophisticated informal learning is taking place online in novel and unexpected ways. In order to understand and analyze in more detail how learning might be occurring, we conducted an in-depth nine-month ethnographic investigation of online fanfiction communities, including participant observation and fanfiction author interviews. Our observations led to the development of a theory we term distributed mentoring, which we present in detail in this paper. Distributed mentoring exemplifies one instance of how networked technology affords new extensions of behaviors that were previously bounded by time and space. Distributed mentoring holds potential for application beyond the spontaneous mentoring observed in this investigation and may help students receive diverse, thoughtful feedback in formal learning environments as well.
description: 14 pages, to be published in Proceedings of the ACM Conference on Computer Supported Cooperative Work 2016
B-mode ultrasound common carotid artery intima-media thickness and external diameter: cross-sectional and longitudinal associations with carotid atherosclerosis in a large population sample
Creators: name: Couper, David
name: Rose, Kathryn M.
Publisher: name: BioMed Central Ltd
Year: 2008

description: Abstract: Background: Arterial diameter and intima-media thickness (IMT) enlargement may each be related to the atherosclerotic process. Their separate or combined enlargement may indicate different arterial phenotypes with different atherosclerosis risk. Methods: We investigated cross-sectional (baseline 1987–89: n = 7956) and prospective (median follow-up = 5.9 years: n = 4845) associations between baseline right common carotid artery (RCCA) external diameter and IMT with existing and incident carotid atherosclerotic lesions detected by B-mode ultrasound in any right or left carotid segments. Logistic regression models (unadjusted, adjusted for IMT, or adjusted for IMT and risk factors) were used to relate baseline diameter to existing carotid lesions while comparably adjusted parametric survival models assessed baseline diameter associations with carotid atherosclerosis progression (incident carotid lesions). Four baseline arterial phenotypes were categorized as having 1) neither IMT nor diameter enlarged (reference), 2) isolated IMT thickening, 3) isolated diameter enlargement, and 4) enlargement of both IMT and diameter. The association between these phenotypes and progression to definitive carotid atherosclerotic lesions was assessed over the follow-up period. Results: Each standard deviation increment of baseline RCCA diameter was associated with increasing carotid lesion prevalence (unadjusted odds ratio [OR] = 1.54, 95% confidence interval [CI] = 1.47–1.62) and with progression of carotid atherosclerosis (unadjusted hazards ratio (HR) = 1.37, 95% CI = 1.28–1.46); and the associations remained significant even after adjustment for IMT and risk factors (prevalence OR = 1.11, 95% CI = 1.04–1.18; progression HR = 1.11, 95% CI = 1.03–1.19). Controlling for gender, age and race, persons with both RCCA IMT and diameter in the upper 50th percentiles had the greatest risk of progressing to clearly defined carotid atherosclerotic lesions (all HR = 1.71, 95% CI = 1.47–2.0; men HR = 1.88, 95% CI = 1.48– 2.39; women HR = 1.59, 95% CI = 1.31–1.95) while RCCA IMT or diameter alone in the upper 50th percentile produced significantly lower estimated risks. Conclusion: RCCA IMT and external diameter provide partially overlapping information relating to carotid atherosclerotic lesions. More importantly, the RCCA phenotype of coexistent wall thickening with external diameter enlargement indicates higher atherosclerotic risk than isolated wall thickening or diameter enlargement.
MeV-Scale Dark Matter Deep Underground
Creators: name: Izaguirre, Eder
name: Krnjaic, Gordan
name: Pospelov, Maxim
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We demonstrate that current and planned underground neutrino experiments could offer a powerful probe of few-MeV dark matter when combined with a nearby high-intensity low-to-medium energy electron accelerator. This experimental setup, an underground beam-dump experiment, is capable of decisively testing the thermal freeze-out mechanism for several natural dark matter scenarios in this mass range. We present the sensitivity reach in terms of the mass-coupling parameter space of existing and planned detectors, such as Super-K, SNO+, and JUNO, in conjunction with a hypothetical 100 MeV energy accelerator. This setup can also greatly extend the sensitivity of direct searches for new light weakly-coupled force-carriers independently of their connection to dark matter.
description: 9 pages, 4 figures
Transverse Force on Quarks in DIS
Creators: name: Burkardt, Matthias
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Generalized Parton Distributions (GPDs) provide information on the distribution of quarks in impact paarmeter space. For transversely polarized nucleons, these impact parameter distributions are transversely distorted and this deviation from axial symmetry leads on average to a net transverse force from the spectators on the active quark in a DIS experiment. %The strength of that force can be related to twist-3 PDFs. This force when acting along the whole trajectory of the active quark leads to a transverse single-spin asymmetries. For a longitudinally polarized nucleon target, the transverse force implies a torque acting on the quark Orbital Angular Momentum (OAM). The resulting change in OAM as the quark leaves the target equals the difference between the Jaffe-Manohar and Ji OAMs.
description: 6 pages, invited talk at DIS2015
title: The role of MRI-CSF flowmetry in differentiation between NPH and involutional brain changes
Creators: name: Abdallah, Amr
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR
subject: MR-Functional imaging
subject: Comparative studies
subject: Cerebrospinal fluid

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of our study is to assess the value of cine-phase contrast MRI CSF flowmetry in cases of normal pressure hydrocephalus (NPH) and to differentiate it from brain...
title: Reducing radiation dose in the diagnosis of pulmonary embolism using adaptive statistical Iterative reconstruction and lowering of tube potential in computed tomography
Creators: name: Kahn, Johannes
Publisher: name: European Congress of Radiology
Year: 2015
Subjects: subject: Radioprotection / Radiation dose
subject: Thorax
subject: CT
subject: CT-Angiography
subject: Computer Applications-Detection, diagnosis
subject: Embolism / Thrombosis

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Acute pulmonary embolism (PE) is a potentially fatal condition, which requires prompt diagnosis. CT angiography (CTA) is considered the diagnostic gold standard. Radiation-associated risks are higher for younger, female patients due to the...