cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Adult hippocampal neural progenitor cells: an Important In vitro tool for studying complex mechanisms regulating adult neurogenesis
Creators: name: SALEM, RITA
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2017

description: Adult hippocampal neurogenesis (ahNG) is a peculiar form of neural plasticity involved in crucial brain functions including cognition, mood and stress response. Adult hippocampal neural progenitor cells (ahNPC) differentiation is modulated positively or negatively by several factors. Understanding the mechanisms regulating ahNG will shed light on its role in brain physiopathology. Astrocytes, one of the major component of the neurogenic niche, might regulate ahNPC fate specification. Little is known about the identity of astrocytes-secreted proteins and the subcellular mechanisms mediating their modulatory effect. Interestingly ahNG is deregulated in neuropsychiatric disorders such as major depression. The specific involvement of serotonin (5-HT) receptors family in mediating antidepressants (AD) effect add more complication into serotonin role in depression and is still not extensively described. Several studies documented a role of NF-?B signaling in ahNPC response to proneurogenic molecules. Yet scarce data described how the knockout of NF-?B p50 subunit (p50KO) could affect ahNG. In vitro analysis of astrocytes conditioned media (ACM) effect on ahNPC differentiation, showed that p50 absence induced intrinsic and extrinsic defects in both cell types. These results could explain earlier study published in our group showing that p50KO mice have reduced ahNG and severe deficits in hippocampal-dependent cognitive performance. Moreover, lipocalin-2 (LCN-2) was identified as a novel astrocyte-derived proneurogenic signal. In the second part of the study we showed that 5-HT2A/2C receptors antagonism and 5-HT7 activation are proneurogenic on ahNPC. Moreover NF-B p50 subunit presence was required for the multimodal AD induced increase of neurogenesis. In conclusion, ahNPC modulation by astrocyte-released factors and serotonin receptors might be future pharmacological targets for increasing ahNG specifically in neurodegenerative and neuropsychiatric disorders.
Experiences, projects and achievements on SES opportunities and technologies for the improvement of wastewater management and reuse including digital tools and solutions
Creators: name: Ciuccoli, Nicolò
Publisher: name: Zenodo
Year: 2025
Subjects: Digitalization
Wastewater management
Digitalization in wastewater treatment plants

description: his presentation belongs to a presentation that was given during the Winter School on 'Consequences of climate change addressed through SES applied to water and wastewater management for increased resiliency and efficiency, and IT solutions or current/circulation models for coastal management', held on 27-31 January 2025 in Ancona, İtaly for SMART4ENV Project.  The winter school lasted for 5 days and Presentations/studies/lectures were presented on the first 2 days on "Wastewater Field", on the 3rd day on "Coastal protection and resilience under the threat of climate change", on the 4th day on "Water and Wastewater" and on the 5th day on "Coastal".

This presentation at the 1st session of the lectures titled "Water and Wastwater Field", held on, Dr. Nicolo Ciuccoli from UNIVPM shared importance of digitalization in wastewater management, Digital solutions for transforming wastewater management, Challenges in implementing digital solutions, Steps for successful implementation, From theory to practice: RealWorld applications and case studies.
sj-pdf-7-msj-10.1177_1352458521996002 – Supplemental material for Which exercise and behavioural interventions show most promise for treating fatigue in multiple sclerosis? A network meta-analysis
Creators: name: Harrison, Anthony M
name: Safari, Reza
name: Mercer, Tom
name: Picariello, Federica
name: van der Linden, Marietta L
name: White, Claire
name: Moss-Morris, Rona
name: Norton, Sam
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-7-msj-10.1177_1352458521996002 for Which exercise and behavioural interventions show most promise for treating fatigue in multiple sclerosis? A network meta-analysis by Anthony M Harrison, Reza Safari, Tom Mercer, Federica Picariello, Marietta L van der Linden, Claire White, Rona Moss-Morris and Sam Norton in Multiple Sclerosis Journal
Carare - D1.3 Annual Report 2010-2011 (Revision 1)
Creators: name: Fernie, Kate
name: Bassett, Sheena
Publisher: name: Zenodo
Year: 2011
Subjects: Archaeology and Architecture
Digital Heritage
Europeana

description: CARARE brings together a network of heritage agencies and organisations, archaeological museums and

research institutions and specialist digital archives from all over Europe to establish an aggregation service for

Europeana. The project’s main objectives are to:

	make digital content for Europe's unique archaeological monuments and historic sites available to
	Europeana’s users;
	establish tools and services to support and enable its network of partners to make their digital content
	interoperable with Europeana, and to share best practices;
	enable access to 3D and Virtual Reality content through Europeana; and
	establish the business model for sustainability.

Summary of Activities

During its first year, the CARARE project has been preparing and enabling the network for harvesting and

aggregation of content for Europeana. Building good communications amongst the partner network began at

the project kick-off meeting in Copenhagen. A survey helped develop understanding of the content held by

CARARE partners and their technical situations. The project has successfully completed conceptual and

technical work to establish the technical architecture of the aggregation services and a CARARE metadata

schema; described in a set of technical deliverables published on the project website. Systems have been

implemented and are being tested ready to support ingestion and mapping of metadata and their storage on the

CARARE repository. Work has been underway to define a methodology for providing 3D and Virtual Reality

content to Europeana. After analysis of the content available, Europeana’s requirements and user needs,

CARARE has recommended 3D PDF as a publishing standard. CARARE has also completed a review of IPR

issues in the content domain and an analysis of the sustainability issues relating to digital content as the first

step in defining a sustainable business models for the aggregation service.

The project is now moving into the next phase with content partners actively planning to make the first

contents available for harvesting in 2011.
sj-docx-1-tab-10.1177_1759720X211034063 – Supplemental material for Predictors of health-related quality of life in musculoskeletal disease patients: a longitudinal analysis
Creators: name: Madrid-García, Alfredo
name: León-Mateos, Leticia
name: Pato, Esperanza
name: Jover, Juan A
name: Fernández-Gutiérrez, Benjamín
name: Abasolo, Lydia
name: Menasalvas, Ernestina
name: Rodríguez-Rodríguez, Luis
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tab-10.1177_1759720X211034063 for Predictors of health-related quality of life in musculoskeletal disease patients: a longitudinal analysis by Alfredo Madrid-García, Leticia León-Mateos, Esperanza Pato, Juan A Jover, Benjamín Fernández-Gutiérrez, Lydia Abasolo, Ernestina Menasalvas and Luis Rodríguez-Rodríguez in Therapeutic Advances in Musculoskeletal Disease
Additional file 2 of High efficacy of chlorfenapyr-based net Interceptor® G2 against pyrethroid-resistant malaria vectors from Cameroon
Creators: name: Tchouakui, Magellan
name: Thiomela, Riccado F.
name: Nchoutpouen, Elysee
name: Menze, Benjamin D.
name: Ndo, Cyrille
name: Achu, Dorothy
name: Tabue, Raymond N.
name: Njiokou, Flobert
name: Joel, Ateba
name: Wondji, Charles S.
Publisher: name: figshare
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Table S1. Abundance of An. funestus obtained after experimental hut trials in Elende, Cameroon from December 2020 to January 2021.
Additional file 3 of High efficacy of chlorfenapyr-based net Interceptor® G2 against pyrethroid-resistant malaria vectors from Cameroon
Creators: name: Tchouakui, Magellan
name: Thiomela, Riccado F.
name: Nchoutpouen, Elysee
name: Menze, Benjamin D.
name: Ndo, Cyrille
name: Achu, Dorothy
name: Tabue, Raymond N.
name: Njiokou, Flobert
name: Joel, Ateba
name: Wondji, Charles S.
Publisher: name: figshare
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3: Table S2a Linear mixed effect model analysis showing different sources of variations that may influenced the exophily. b Linear mixed effect model analysis showing different sources of variations that may influence the blood feeding. c Linear mixed model effect analysis showing different sources of variations that may influenced the mortality.
Supplemental Material, sj-pdf-2-jpx-10.1177_23743735211034047 - Improving Communications With Patients and Families in Geriatric Care. The How, When, and What
Creators: name: Huang, Shirley Chien-Chieh
name: Morgan, Alden
name: Peck, Vanessa
name: Khoury, Lara
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Medicine

description: Supplemental Material, sj-pdf-2-jpx-10.1177_23743735211034047 for Improving Communications With Patients and Families in Geriatric Care. The How, When, and What by Shirley Chien-Chieh Huang, Alden Morgan, Vanessa Peck and Lara Khoury in Journal of Patient Experience
Organization and ELISA-Based Results of the First Proficiency Testing to Evaluate the Ability of European Union Laboratories to Detect Staphylococcal Enterotoxin Type B (SEB) in Buffer and Milk
Creators: name: Nia, Yacine
name: Rodriguez, Mélanie
name: Zeleny, Reinhard
name: Herbin, Sabine
name: Auvray, Frédéric
name: Fiebig, Uwe
name: Avondet, Marc-André
name: Munoz, Amalia
name: Hennekinne, Jacques-Antoine
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2016
Subjects: subject: proficiency test
subject: staphylococcal enterotoxin B
subject: bioterrorism agent
subject: ELISA methods
subject: 610 Medizin

description: The aim of this work was to organize the first proficiency test (PT) dedicated to staphylococcal enterotoxin B (SEB) detection in milk and buffer solutions. This paper describes the organization of the PT trial according to EN ISO 17043 requirements. Characterization of the SEB stock solution was performed using SDS-PAGE and SE-specific ELISA, and amino acid analysis was used to assign its protein concentration. The solution was then used to prepare six PT materials (four milk and two buffer batches) at a ng/g toxin level, which included one blank and one SEA-containing milk as specificity control. Suitable material homogeneity and stability were assessed using screening and quantitative ELISAs. Among the methods used by the participants, ELISA-based methods demonstrated their efficiency for the detection of SEB in both simple and complex matrices. The results serve as a basis for further improving the detection capabilities in expert laboratories and can therefore be considered as a contribution to biopreparedness.
Changes in Waist Circumference among German Adults over Time - Compiling Results of Seven Prospective Cohort Studies
Creators: name: Haftenberger, Marjolein
name: Mensink, Gert
name: Vogt, S.
name: Thorand, Barbara
name: Peters, Annette
name: Herzog, B.
name: Hartwig, Saskia
name: Greiser, Karin Halina
name: Ittermann, T.
name: Schipf, Sabine
name: Völzke, Henry
name: Merz, Benedikt
name: Nöthlings, Ute
name: Koch, M.
name: Neamat-Allah, J.
name: Katzke, V.
name: Kaaks, R.
name: Boeing, Heiner
name: Bachlechner, Ursula
name: Scheidt-Nave, Christa
name: Schienkiewitz, Anja
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: Germany
subject: Population-based
subject: Waist circumference
subject: Central obesity
subject: Prospective cohort studies
subject: 610 Medizin

description: Aim: This study aims to quantify longitudinal changes in waist circumference (WC) among adults aged 45-64 years in Germany. Methods: Data of 15,444 men and 17,207 women from one nationwide and six regional prospective German cohort studies were analyzed. The sex-specific mean change in WC per year of follow-up was assessed for each study separately. Findings from the cohort-by-cohort analysis were combined by applying meta-analytic methods. Progression to central obesity (WC ≥ 102 cm in men and ≥ 88 cm in women) within a standardized period of 10 years was described for each study. Results: The estimated mean change in WC per year of follow-up for all cohorts combined was 0.53 (95% confidence interval 0.29-0.76) cm/year for men and 0.63 (0.48-0.77) cm/year for women, but varied between the included studies. Within 10 years, about 20% of individuals with low WC Conclusion: The increase in mean WC with aging along with a profound increase of central adiposity is obviously and may have several adverse health effects. Obesity prevention programs should also focus on abdominal obesity.
Changes in physical functioning among men and women aged 50–79 years in Germany: an analysis of National Health Interview and Examination Surveys, 1997–1999 and 2008–2011
Creators: name: Buttery, Amanda K.
name: Du, Yong
name: Busch, Markus
name: Fuchs, Judith
name: Gaertner, Beate
name: Knopf, Hildtraud
name: Scheidt-Nave, Christa
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: DEGS1
subject: Physical functioning
subject: Chronic disease
subject: Multimorbidity
subject: Disability
subject: GNHIES98
subject: 610 Medizin

description: Background: This study examines changes in physical functioning among adults aged 50-79 years in Germany based on data from two German National Health Interview and Examination Surveys conducted in 1997–1999 (GNHIES98) and 2008–2011 (DEGS1). Methods Using cross-sectional data from the two surveys (GNHIES98, n = 2884 and DEGS1, n = 3732), we examined changes in self-reported physical functioning scores (Short Form-36 physical functioning subscale (SF-36 PF)) by sex and age groups (50–64 and 65–79 years). Covariables included educational level, living alone, nine chronic diseases, polypharmacy (≥5 prescribed medicines), body mass index, sports activity, smoking and alcohol consumption. Multimorbidity was defined as ≥2 chronic diseases. Multivariable models were fitted to examine consistency of changes in physical functioning among certain subgroups and to assess changes in mean SF-36 PF scores, adjusting for changes in covariables between surveys. Results: Mean physical functioning increased among adults aged 50–79 years between surveys in unadjusted analyses, but this change was not as marked among men aged 65–79 years who experienced rising obesity (20.6 to 31.5%, p = 0.004) and diabetes (13.0 to 20.0%, p = 0.014). Prevalence of multimorbidity and polypharmacy use increased among men and women aged 65–79 years. In sex and age specific multivariable analyses, changes in physical functioning over time were consistent across subgroups. Gains in physical functioning were explained by improved education, lower body mass index and improved health-related behaviours (smoking, alcohol consumption, sports activity) in women, but less so among men. Conclusions: Physical functioning improved in Germany among adults aged 50–79 years. Improvements in the population 65–79 years were less evident among men than women, despite increases in multimorbidity prevalence among both sexes. Changes in health behaviours over time differed between sexes and help explain variations in physical functioning. Targeted health behaviour interventions are indicated from this study.
sj-pdf-1-ajs-10.1177_03635465211026623 – Supplemental material for Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial
Creators: name: Bayer, Monika L.
name: Hoegberget-Kalisz, Maren
name: Svensson, Rene B.
name: Hjortshoej, Mikkel H.
name: Olesen, Jens L.
name: Nybing, Janus D.
name: Boesen, Mikael
name: Magnusson, S. Peter
name: Kjaer, Michael
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465211026623 for Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial by Monika L. Bayer, Maren Hoegberget-Kalisz, Rene B. Svensson, Mikkel H. Hjortshoej, Jens L. Olesen, Janus D. Nybing, Mikael Boesen, S. Peter Magnusson and Michael Kjaer in The American Journal of Sports Medicine
Weiterer verstärkter Anstieg von Syphilis-Infektionen bei Männern, die Sex mit Männern haben
Creators: name: Koch-Institut, Robert
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: 610 Medizin

description: Die Syphilis ist eine bakterielle, durch die Spirochätenart Treponema pallidum verursachte Erkrankung, die nur beim Menschen vorkommt und sexuell, durch Blut und intrauterin von der Mutter auf das Kind übertragbar ist. Sie verläuft typischerweise in drei Stadien: Ein sogenannter Primäraffekt (ein meist schmerzloses Geschwür an der Eintrittsstelle) bildet sich wenige Tage bis Wochen nach der Infektion. Im Sekundärstadium macht sich die Erkrankung durch Allgemeinsymptome und Hauterscheinungen bemerkbar und im Tertiärstadium (Jahre nach der Erstinfektion) kann es zur Schädigung des Gehirns und der Blutgefäße kommen. Symptomfreie Phasen werden als Latenz bezeichnet. In Abhängigkeit von der seit der Infektion vergangenen Zeitspanne wird zwischen Früh- (bis etwa ein Jahr nach der Infektion) und Spätlatenz unterschieden. Infektiös sind Personen im Primär- und Sekundärstadium sowie während der Frühlatenz. Die Infektion kann durch Antibiotika geheilt werden; wiederholte Infektionen sind möglich.
The Power of Pro-Palestine Consumer Activism: Analyzing the Boycott Movement and Its Apps since October 2023
Creators: name: Mohamed Buheji
Publisher: name: Zenodo
Year: 2025
Subjects: Boycott Movement, Israel Occupation Economy, Boycott Apps, BDS (Boycott, Divestment, and Sanctions), War on Gaza 2023, Economic Impact, Consumer Behavior, Sustained Boycotts.

description: Abstract

This paper examines the impacts of the boycott movement against the Israeli occupation in the first 18 months following the outbreak of the war on Gaza in October 2023. Drawing on the published data, trends, and global attitudes, the study highlights how grassroots activism, corporate accountability, and international solidarity with Palestinians have shaped the outcomes of the boycott. The research focuses on key sectors of the Israeli economy, such as agriculture, technology, and consumer goods, which have experienced declines in sales, reduced foreign investment, and stock market volatility due to the boycott. Additionally, the paper explores the broader implications of the boycott, including its effects on Israel’s global reputation. The study analyses the role and the changes in consumer awareness and behaviour that are influenced by the boycott Apps. Despite the challenges in maintaining long-term intensity, the boycott has fostered global solidarity with Palestinians and heightened ethical consumerism. Therefore, the author reviews all types of existing applications and their capacity in helping to sustain the boycott movement. The author concludes that the boycott has significant potential to influence consumers' awareness and behaviour, particularly if sustained and coordinated across economic and cultural spheres using platforms that capitalise on further Apps development. The research underscores the importance of continued efforts to amplify the boycott’s effectiveness in achieving its goals.
sj-pdf-3-taw-10.1177_20420986211030371 – Supplemental material for Inappropriate medications and physical function: a systematic review
Creators: name: Manias, Elizabeth
name: Kabir, Md Zunayed
name: Maier, Andrea B.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-pdf-3-taw-10.1177_20420986211030371 for Inappropriate medications and physical function: a systematic review by Elizabeth Manias, Md Zunayed Kabir and Andrea B. Maier in Therapeutic Advances in Drug Safety
Decline in the proportion of methicillin resistance among Staphylococcus aureus isolates from non-invasive samples and in outpatient settings, and changes in the co-resistance profiles: an analysis of data collected within the Antimicrobial Resistance Surveillance Network, Germany 2010 to 2015
Creators: name: Walter, Jan
name: Noll, Ines
name: Feig, Marcel
name: Weiss, Bettina
name: Claus, Hermann
name: Werner, Guido
name: Eckmanns, Tim
name: Hermes, Julia
name: Sin, Muna Abu
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger; Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: Germany
subject: Surveillance
subject: MRSA
subject: Antimicrobial resistance
subject: Methicillin-resistant
subject: Staphylococcus aureus (MRSA)
subject: Livestock-associated
subject: 610 Medizin

description: Background: Recent analysis of trends of non-invasive infections with methicillin resistant Staphylococcus aureus (MRSA), of trends of MRSA infections in outpatient settings and of co-resistance profiles of MRSA isolates are scarce or lacking in Germany. Methods: We analysed data from the Antimicrobial Resistance Surveillance Network (ARS). We included in the analysis the first isolate of S. aureus per patient and year, which had a valid test result for oxacillin resistance and which was not a screening sample. We limited the analysis to isolates from facilities, which contributed to ARS for all six years between 2010 and 2015. We compared the proportion of methicillin resistance among S. aureus isolates by calendar year using Chi-square and Fisher’s exact test. We corrected for multiple testing using the Bonferroni correction. We stratified the analysis by sample type including various non-invasive sample types and by type of care (e.g. hospital versus outpatient clinic). We also analysed the non-susceptibility of MRSA to selected antibiotics. Results: The analysis included 148,561 S. aureus isolates. The distribution of these isolates by sex, age, region, sample type, clinical speciality and type of care remained relatively stable over the six years analysed. The proportion of MRSA among S. aureus isolates decreased continuously from 16% in 2010 to 10% in 2015. This decrease was seen for all types of care and for the majority of sample types, including the outpatient clinic (12 to 8%), as well as blood culture (19 to 9%), urine samples (25 to 15%), swabs (14 to 9%), respiratory samples (22 to 11%) and lesions (15 to 10%). The non-susceptibility of MRSA isolates to tobramycin (47 to 32%), ciprofloxacin (95 to 89%), moxifloxacin (94 to 84%), clindamycin (80 to 71%) and erythromycin (81 to 72%) declined markedly, but it increased for tetracyclines (6 to 9%) and gentamicin (3 to 6%). Non-susceptibility of MRSA to linezolid, teicoplanin, tigecycline and vancomycin remained rare. Conclusion: This analysis indicates that the incidence of MRSA infections declined in a variety of settings in Germany between 2010 and 2015 and that the co-resistance profiles of MRSA isolates changed markedly.
sj-docx-1-cjk-10.1177_20543581211019640 – Supplemental material for The Association of Matrix Metalloproteinases With Acute Kidney Injury Following CPB-Supported Cardiac Surgery
Creators: name: McNair, Erick D.
name: Bezaire, Jennifer
name: Moser, Michael
name: Mondal, Prosanta
name: Conacher, Josie
name: Franczak, Aleksandra
name: Sawicki, Greg
name: Reid, David
name: Khani-Hanjani, Abass
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, sj-docx-1-cjk-10.1177_20543581211019640 for The Association of Matrix Metalloproteinases With Acute Kidney Injury Following CPB-Supported Cardiac Surgery by Erick D. McNair, Jennifer Bezaire, Michael Moser, Prosanta Mondal, Josie Conacher, Aleksandra Franczak, Greg Sawicki, David Reid and Abass Khani-Hanjani in Canadian Journal of Kidney Health and Disease
Eine Schätzung der Prävalenz von Tuberkulose bei Asylsuchenden in Deutschland
Creators: name: Stadtmüller, Sven
name: Schröder, Jette
name: Ehlers, Stefan
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: Tuberkulose
subject: Asyl
subject: 610 Medizin

description: Seit 2013 ist in Deutschland die Anzahl der gemeldeten Erkrankungsfälle von Tuberkulose (TB) angestiegen.1 Besonders markant gestaltete sich die Zunahme im Jahr 2015: Mit knapp 6.000 Neuerkrankungen belief sich der Zuwachs gegenüber dem Vorjahr auf nahezu 30 %.2 Im Jahr 2016 hat sich die Anzahl der Neuerkrankungen im Vergleich zu 2015 nur wenig geändert.3 Mit dem Anstieg der Fallzahlen geht zugleich eine veränderte demografische Struktur der Erkrankten einher. Der Anteil an TB-Neuerkrankten, die nicht in Deutschland geboren wurden, betrug zwischen 2002 und 2012 40 – 50 % und nahm bis zum Jahr 2015 auf 72,1 % zu.2 Der Anstieg der TB-Inzidenz kann daher auch mit der hohen Anzahl an Menschen, die im Rahmen der Migrationsbewegungen in den Jahren 2014 und 2015 nach Deutschland gekommen sind, erklärt werden.2,4 Gestützt wird diese Vermutung darüber hinaus durch den Umstand, dass im Jahr 2015 im Rahmen der Untersuchung auf TB für das nach § 36 Abs. 4 Infektionsschutzgesetz (IfSG) geforderte ärztliche Zeugnis, z. B. durch Röntgenscreenings von Asylsuchenden, die in eine Gemeinschaftsunterkunft aufgenommen werden sollen, insgesamt 1.255 Tuberkulosen diagnostiziert wurden. Im Jahr zuvor waren dies 419 Fälle, 2013 lediglich 216 Fälle. Für 99,3 (2014) bzw. 95,0 % (2015) dieser im Rahmen eines solchen Screenings erfassten Erkrankungsfälle wurden dem Robert Koch-Institut (RKI) Angaben zum Geburtsland übermittelt. 2,5,6 Anhand der absoluten Anzahl an TB-Fällen nach Herkunftsland lassen sich jedoch keine Aussagen zur Prävalenz von TB bei Geflüchteten aus verschiedenen Herkunftsländern bei deren Aufnahme in eine Gemeinschaftsunterkunft in Deutschland treffen. Dies liegt daran, dass nicht zentral erfasst wird, bei wie vielen Menschen aus den einzelnen Herkunftsländern eine Röntgenuntersuchung nach § 36 Abs. 4 IfSG durchgeführt wurde. Für eine bessere Einschätzung des TB-Vorkommens in Deutschland wären Zahlen zur Prävalenz der TB für Geflüchtete aus den verschiedenen Herkunftsländern bei geplanter Aufnahme in Gemeinschaftsunterkünfte jedoch hilfreich. Das Ziel dieses Beitrags ist es, die Prävalenz der TB für Geflüchtete unterschiedlicher Herkunft zu schätzen. Zugleich sollen unsere Schätzungen mit Daten der Weltgesundheitsorganisation (WHO) verglichen und Ursachen für Unterschiede erörtert werden. Schließlich werden im Rahmen des vorliegenden Artikels die möglichen Konsequenzen, die aus den vorgelegten Schätzungen gezogen werden könnten, diskutiert
Robust Ant Colony Based Routing Algorithm for Mobile Ad-hoc Networks
Creators: name: Sharma, Arush S
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Digital processor architectures
Other information and computing sciences not elsewhere classified

description: This thesis discusses about developing a routing protocol of mobile ad hoc networks in a bio inspired manner. Algorithms inspired by collective behaviour of social insect colonies, bird flocking, honey bee dancing, etc., promises to be capable of catering to the challenges faced by tiny wireless sensor networks. Challenges include but are not limited to low bandwidth, low memory, limited battery life, etc. This thesis proposes an energy efficient multi-path routing algorithm based on foraging nature of ant colonies and considers many other meta-heuristic factors to provide good robust paths from source node to destination node in a hope to overcome the challenges posed by resource constrained sensors.
Additional file 1 of Clinical perspectives and outcomes of the giant breast phyllodes tumor and sarcoma: a real-world retrospective study
Creators: name: Liu, Naiquan
name: Kang, Ye
name: Qu, Ningxin
name: Kong, Chenhui
name: Han, Ye
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Biotechnology
Mathematical Sciences not elsewhere classified
Cancer

description: Additional file 1: Supplement 1. Hematoxylin and eosin staining of the giant sarcoma with negative result (original magnification, 200×)
Additional file 1 of GNNMF: a multi-view graph neural network for ATAC-seq motif finding
Creators: name: Zhang, Shuangquan
name: Wu, Xiaotian
name: Lian, Zhichao
name: Zuo, Chunman
name: Wang, Yan
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Supplementary Material 1.
Clinical relevance and function of HMGB1 gene polymorphism and expression in colorectal cancer
Creators: name: Wang, Fang
name: Huang, Zhijun
name: Li, Jianping
name: Gao, Xueren
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: High HMGB1 levels contribute to the development and metastasis of tumors such as colorectal cancer (CRC). The current investigation sought to evaluate the association of a functional InDel polymorphism (rs34000982) on the HMGB1 gene with CRC susceptibility and tumor stage and the clinical relevance of HMGB1 gene expression. A total of 600 CRC patients and 600 healthy control individuals were genotyped by a polymerase chain reaction-polyacrylamide gel electrophoresis assay. The findings demonstrated that the rs34000982 Ins allele or Ins/Ins genotype was associated not only with reduced susceptibility to CRC, especially stage III-IV CRC (Ins vs. Del: OR = 0.65, 95%CI = 0.51-0.82, p < 0.001; Ins/Ins vs. Del/Del: OR = 0.29, 95%CI = 0.14- 0.60, p < 0.001), but also with tumor stage. CRC patients carrying the Ins allele or Ins/Ins genotype had a significantly lower risk of stage III-IV tumors (Ins vs. Del: OR = 0.69, 95%CI = 0.53- 0.91; Ins/Ins vs. Del/Del: OR = 0.41, 95%CI = 0.18-0.94). Functional research revealed that the rs34000982 Ins allele enabled hsa-miR-944 to interact with the 3’ untranslated region of HMGB1. In addition, HMGB1 gene expression levels were associated not only with multiple immune cell infiltration, but also with multiple anti-CRC drug sensitivities. The current findings suggest that the HMGB1 rs34000982 polymorphism may serve as a marker of CRC susceptibility and progression in the Chinese population, and HMGB1 levels may serve as an anti-CRC drug sensitivity marker.
IMPROVING PATIENTS EXPERIENCE IN AN EMERGENCY DEPARTMENT USING SYSTEMS ENGINEERING APPROACH
Creators: name: Khazaei, Hosein
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Healthcare industry in United States of America is facing a big paradox. Although US is a leader in the industry of medical devices, medical practices and medical researches, however there isnt enough satisfaction and quality in performance of US healthcare operations. Despite the big investments and budgets associated with US healthcare, there are big threats to US healthcare operational side, that reduces the quality of care. In this research study, a step by step Systems Engineering approach is applied to improve healthcare delivery process in an Emergency Department of a hospital located in Indianapolis, Indiana. In this study, different type of systems engineering tools and techniques are used to improve the quality of care and patients satisfaction in ED of Eskenazi hospital. Having a simulation model will help to have a better understanding of the ED process and learn more about the bottlenecks of the process. Simulation model is verified and validated using different techniques like applying extreme and moderate conditions and comparing model results with historical data. 4 different what if scenarios are proposed and tested to find out about possible LOS improvements. Additionally, those scenarios are tested in both regular and an increased patient arrival rate. The optimal selected what-if scenario can reduce the LOS by 37 minutes compared to current ED setting. Additionally, by increasing the patient arrival rate patients may stay in the ED up to 6 hours. However, with the proposed ED setting, patients will only spend an additional 106 minutes compared to the regular patient arrival rate.
Digital Health in Maternal Health: Systematic Review Synthesized by Synthory AI
Creators: name: Synthory AI
Publisher: name: Zenodo
Year: 2024

description: This review was automatically synthesized for research purposes using the Synthory AI service, following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The systematic literature review focused on digital health in maternal health, specifically addressing digital interventions for gestational diabetes and telemedicine for mental health during pregnancy. The review was based on primary research studies published between 2019 and 2024, retrieved from PubMed and PubMed Central™ databases.
Lo scritto che imita il parlato: i manuali di conversazione dal ?400 al ?700 e la loro importanza per la storia dell'italiano parlato
Creators: name: FRANCESCHINI, RITA
Publisher: name: Universit� degli studi di Bergamo
Year: 2002

description: L?articolo si prefigge di presentare un oggetto di studio di grammaticografia che in Italia non ha trovato ancora molta considerazione: ossia lo studio delle grammatiche d?uso consacrate all?italiano come ?lingua straniera? dal ?400 al ?700. Con esempi tratti dai "Dialoghi di Giorgio da Norimberga" e dai libri di Dulcis, Fabro e Du�z, fino al diffusissimo ?Veneroni?, nel contributo si analizzano soltanto le parti dialogate in questi manuali pratici che erano diretti soprattutto a commercianti, aristocratici, pellegrini in viaggio in Italia. I dialoghi erano concepiti come esercizi atti a supplire all?interlocutore nativo mancante, e trattano di questioni pratiche (ed amene). L?interesse linguistico risiede nel fatto che i dialoghi dovevano presentare al discente un italiano comune, spendibile a fini conversazionali sull?intera penisola. Per questo motivo i dialoghi formano una base documentaria di grande interesse per lo studio della storia della lingua d?uso comune in Italia, anche se il loro carattere autentico va vagliato con massima cautela. Essi vanno comunque ad ampliare la base per una pragmatica diacronica.
Additional file 1 of Extensive lesions and a positive cone margin are strong predictors of residual disease in subsequent hysterectomy following conization for squamous intraepithelial lesion grade 2 or 3 study design
Creators: name: Peng, Hongfa
name: Liu, Wencan
name: Jiang, Jingjing
name: Du, Hui
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional File 1: Table 1 and Table 2
Supplemental Material, sj-pdf-3-ptd-10.1177_0896860820982218 - ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: Classification, measurement, interpretation and rationale for intervention
Creators: name: Morelle, Johann
name: Stachowska-Pietka, Joanna
name: Öberg, Carl
name: Gadola, Liliana
name: La Milia, Vincenzo
name: Yu, Zanzhe
name: Lambie, Mark
name: Mehrotra, Rajnish
name: de Arteaga, Javier
name: Davies, Simon
Publisher: name: SAGE Journals
Year: 2023
Subjects: Medicine

description: Supplemental Material, sj-pdf-3-ptd-10.1177_0896860820982218 for ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults: Classification, measurement, interpretation and rationale for intervention by Johann Morelle, Joanna Stachowska-Pietka, Carl Öberg, Liliana Gadola, Vincenzo La Milia, Zanzhe Yu, Mark Lambie, Rajnish Mehrotra, Javier de Arteaga and Simon Davies in Peritoneal Dialysis International
sj-pdf-1-taw-10.1177_20420986211030371 – Supplemental material for Inappropriate medications and physical function: a systematic review
Creators: name: Manias, Elizabeth
name: Kabir, Md Zunayed
name: Maier, Andrea B.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-pdf-1-taw-10.1177_20420986211030371 for Inappropriate medications and physical function: a systematic review by Elizabeth Manias, Md Zunayed Kabir and Andrea B. Maier in Therapeutic Advances in Drug Safety
Characterization of mouse models to study the pathogenesis of celiac disease and the role played by the dysregulation of the intestinal microbiota
Creators: name: FERRARI, Eleonora
Publisher: name: Universit� degli Studi del Piemonte Orientale Amedeo Avogadro
Year: 2021

description: Celiac disease (CD) is a permanent intolerance to dietary protein, gluten, from wheat rye and barley. It occurs in about 1% worldwide population, in genetically predisposed individuals bearing human leukocyte antigen DQ2/DQ8. Although gut epithelial cell stress and the innate immune activation are responsible for the breaking oral tolerance to gliadin, the gluten component, the exact mechanisms through which gliadin can stimulate CD onset are still unclear. Here I show how is important to identify in vivo preclinical models of CD to study its pathogenesis, at molecular level. The increasing prevalence of positive serological marker of CD in Cystic Fibrosis (CF) affected patients let to the hypothesis of a link between the two disorders. Results from my studies indicate that CFTR is potentially involved in the pathogenesis of CD, with gliadin peptides inhibiting CFTR activity and expression. Today, the only treatment for CD is a long-term gluten-free diet. Several evidences show that an altered composition of the intestinal microbiota could play a key role in the pathogenesis of CD, through the modulation of intestinal permeability and the regulation of the immune system. Indeed, although further studies are still required to unveil the molecular mechanisms, results reported in the present work clearly indicate that rebalancing the gut microbiota composition by probiotics administration might represent a new strategy to treat CD affected patients.
sj-pdf-1-imr-10.1177_03000605211021278 - Supplemental material for A prospective, observational study of fidaxomicin use for Clostridioides difficile infection in France
Creators: name: Guery, Benoit
name: Berger, Pierre
name: Gauzit, Remy
name: Gourdon, Magali
name: Barbut, Frédéric
name: DAFNE Study Group:
name: Bémer, Pascale
name: Bessède, Emilie
name: Camou, Fabrice
name: Cattoir, Vincent
name: Couzigou, Carine
name: Descamps, Dominique
name: Dinh, Aurélien
name: Laurans, Caroline
name: Lavigne, Jean-Philippe
name: Lechiche, Catherine
name: Leflon-Guibout, Véronique
name: Le Monnier, Alban
name: Levast, Marion
name: Mootien, Joy Yoganaden
name: N’Guyen, Yohan
name: Piroth, Lionel
name: Prazuck, Thierry
name: Rogeaux, Olivier
name: Roux, Anne-Laure
name: Vachée, Anne
name: Vernet Garnier, Véronique
name: Wallet, Frédéric
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-imr-10.1177_03000605211021278 for A prospective, observational study of fidaxomicin use for Clostridioides difficile infection in France by Benoit Guery, Pierre Berger, Remy Gauzit, Magali Gourdon, Frédéric Barbut, for the DAFNE study group DAFNE study group:, Pascale Bémer, Emilie Bessède, Fabrice Camou, Vincent Cattoir, Carine Couzigou, Dominique Descamps, Aurélien Dinh, Caroline Laurans, Jean-Philippe Lavigne, Catherine Lechiche, Véronique Leflon-Guibout, Alban Le Monnier, Marion Levast, Joy Yoganaden Mootien, Yohan N’Guyen, Lionel Piroth, Thierry Prazuck, Olivier Rogeaux, Anne-Laure Roux, Anne Vachée, Véronique Vernet Garnier and Frédéric Wallet in Journal of International Medical Research
Design and synthesis of fluorescence-labeled nucleotide with a cleavable aryl-triazene linker for DNA sequencing by synthesis
Creators: name: Tang, Bo-Wei
name: Wang, Ping-Yang
name: Shen, Yu-Mei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified

description: A novel acid-cleavable triazene linker was synthesized and then reacted with modified 2′-deoxyuridine triphosphate (dUTP), followed by Cy3 NHS ester, the final product serves as an excellent reversible terminator for DNA sequencing by synthesis (DNA SBS). The synthesized dye-labeled terminator incorporated into DNA strand faithfully in a DNA-elongation, and the fluorophore incorporated into DNA strands was cleaved completely under weak acidic conditions within short time. Further the first cleaved product can be incorporated with 100% efficiency for the second time. These preliminary evaluations show that the triazene reversible terminator has a great potential value in DNA sequencing.
Additional file 1 of Priority setting to support a public health research agenda: a modified Delphi study with public health stakeholders in Germany
Creators: name: Hoekstra, Dyon
name: Gerhardus, Ansgar
name: Lhachimi, Stefan K.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. List of organisations that were invited to participate in the study—by stakeholder group. We identified specific organisations that fall within each of the included stakeholder groups. The stakeholder groups stand for different professional fields who are either producers, facilitators, or consumers of public health research in Germany. We used this list of organisations for the recruitment of individual respondents for the Delphi stage.
PSYCHOLOGICAL NEEDS SATISFACTION: EVALUATING THE MODERATING EFFECTS OF SOURCE AND DOMAIN OF NEED SATISFACTION ON JOB ATTITUDES
Creators: name: Law-penrose, Jared Collis
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Industrial and organisational psychology (incl. human factors)
Behavioural neuroscience

description: This research examines the relationships between the satisfaction of psychological needs (belongingness and distinctiveness) on affective and cognitive attitudes (job satisfaction and commitment) with an emphasis on identifying key differential and moderating effects. This study hypothesizes the direct effects of need satisfaction and moderating effects of the source (individual & group) and domain (work & non-work) of need satisfaction. Hypotheses were tested with a cross-sectional survey of alumni from a regional college in the mid-Atlantic United States. Results indicated that satisfying the needs for belongingness and distinctiveness whether through source (individual vs. group) or by domain (work vs. non-work) have a positive impact on job attitudes. However, the results for the moderating and differential effects along with post-hoc analyses provides additional insights. Overall, this study found that the satisfaction of psychological needs have important direct effects on affective and cognitive job attitudes. Results indicated that the source of need satisfaction (individual and group) and the domain in which a need is satisfied do moderate the relationship between psychological need satisfaction and specific cognitive and affective job attitudes. In many circumstances, the moderating effect was not as expected. Additionally, the context of virtuality had a significant impact on only a few relationships. Post-hoc analyses showed that the relationship among the variables in this study are more complex than hypothesized and should be evaluated more fully.