cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Customized Design Optimization & Additive Manufacturing for Revision Arthroplasty
Creators: name: Sikandar M. Usman
Publisher: name: Zenodo
Year: 2019
Subjects: Additive Manufacturing, Acetabular Cup, Revision Arthroplasty, Generative Design

description: Total hip replacement is one of the most successful surgeries performed in orthopedics. It is an effective procedure that can cure hips that have been damaged by arthritis, a fracture, or other conditions e.g. Accidents, Injuries. High Impact Exercises, etc. It usually lasts longer, however, a hip replacement can fail for a variety of reasons. In that case, a doctor often recommends another operation; It involves generally acetabular cup revision. Therefore, the demand of acetabular cup revision typically increases with the increase in total hip arthroplasty. The poster presents a study on the use of generative design and additive manufacturing for custom acetabular cup revisions. Acetabular cup revisions are surgeries to replace the acetabular cup, which is the cup-shaped part of the hip implant. These surgeries can be complex and challenging. The study used Autodesk Fusion 360 to design acetabular cup revisions using generative design. The results showed that generative design can lead to a 30-40% reduction in the mass of the acetabular cup. The lightweight acetabular cups also showed more flexible behavior and almost similar fatigue performance. The generative design and additive manufacturing have the potential to improve the outcome of acetabular cup revisions. However, we acknowledge that more research is needed to validate their findings in clinical trials.
description: 11th Santa Kalman Scientific Conference 2019
title: Plasma technology for the production of superconducting thin films in accelerator applications
Creators: name: Walk, Felix
Publisher: name: University of Liverpool Repository
Year: 2023

description: Energetic ion bombardment in plasma deposition is a key feature in tailoring specific microstructures, crystallographic orientations and phases of thin films. The high-power impulse magnetron sputtering (HiPIMS) technique is considered an ionised physical vapor deposition (PVD) process, where a substantial amount of metal ions contribute to the growth process. It has already been successfully used to produce superconducting radio frequency (SRF) cavities, but ion energy control via substrate biasing is not always viable. The newly emerged technique of bipolar HiPIMS, where a reverse positive voltage follows the negative HiPIMS pulse, is overcoming this issue for grounded substrates. The aim of this thesis is to take a plasma diagnostic approach to the deposition of superconducting thin films. The bipolar HiPIMS discharge is analysed by means of Langmuir probe and retarding field energy analyser (RFEA) measurements and produced samples are characterised via scanning electron microscopy (SEM), with electron backscatter diffraction (EBSD) analysis and tested on their superconducting properties via a vibrating sample magnetometer (VSM).
On the coupling between buoyancy forces and electroconvective instability near ion-selective surfaces
Creators: name: Karatay, Elif
name: Wessling, Matthias
name: Mani, Ali
Publisher: name: arXiv
Year: 2016
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Recent investigations have revealed that ion transport from aqueous electrolytes to ion-selective surfaces is subject to electroconvective instability that stems from coupling of hydrodynamics with electrostatic forces. Electroconvection is shown to enhance ion mixing and the net rate of transport. However, systems subject to electroconvection inherently involve fluid density variation set by salinity gradient in the bulk fluid. In this study we thoroughly examine the interplay of gravitational convection and chaotic electroconvection. Our results reveal that buoyant forces can significantly influence the transport rates, otherwise set by electroconvection, when the Rayleigh number $Ra$ of the system exceeds a value $Ra \sim 1000$. We show that buoyancy forces can significantly alter the flow patterns in these systems. When the buoyancy acts in the stabilizing direction, it limits the extent of penetration of electroconvection, but without eliminating it. When the buoyancy destabilizes the flow, it alters the electroconvective patterns by introducing upward and downward fingers of respectively light and heavy fluid.
title: Die Hemmung der periartikulären periartikulären Demineralisation durch eine Therapie mit Certolizumab Pegol ist mit einer klinischen Remission der rheumatoiden Arthritis verbunden
Creators: name: Pfeil, Alexander
name: Nussbaum, Anica
name: Jung, Christian
name: Reinhardt, Lisa
name: Renz, Diane
name: Malich, Ansgar
name: Oelzner, Peter
name: Wolf, Gunter
name: Böttcher, Joachim
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Rheumatoide Arthritis
subject: Digitale Radiogrammetrie
subject: periartikuläre Demineralisation
subject: Certolizumab Pegol
subject: klinische Remission
subject: 610 Medical sciences; Medicine

description: Einleitung: Die Digitale Radiogrammetrie ist eine etablierte Methode zur Beurteilung der periartikulären Demineralisation. Die Therapie mit dem TNF-α Blocker Certolizumab Pegol zählt zu den effektiven Therapien in der Behandlung von Patienten mit einer rheumatoiden Arthritis (RA). Im[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Table S1 from Latitudinal cline of death-feigning behaviour in a beetle (Tribolium castaneum)
Creators: name: Matsumura, Kentarou
name: Miyatake, Takahisa
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: Name, latitude, longitude, annual temperature, and sample size of each place from where the populations of T. castaneum were captured.
title: Prospektive Einjahresstudie zur Wirksamkeit von Infliximab Biosimilar bei mit Remicade vorbehandelten Patienten mit entzündlich rheumatischen Erkrankungen
Creators: name: Kellner, Herbert
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: rheumatoide Arthritis
subject: Spondylitis ankylosans
subject: Arthritis psoriatica
subject: iInfliximab
subject: iInfliximab Biosimilar
subject: 610 Medical sciences; Medicine

description: Einleitung: Seit Februar 2015 ist der CT-P13 Antikörper als Infliximab Biosimilar in Deutschland für alle bisherigen rheumatologischen Indikationsbereiche des Originalpräparats Remicade® zugelassen und verfügbar. Zulassungsstudien bei der RA und AS konnten eine vergleichbare[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Interfaces da Ciência Cidadã com a ciência da Informação brasileira: mapeamento da temática na base de dados referencial de artigos de periódicos em ciência da informação
Creators: name: Santos, Vinícios Ribeiro Soares dos
name: Vogel, Michely Jabala Mamede
Publisher: name: Zenodo
Year: 2023

description: Apresentação realizada na sessão “O meu Póster em 30 segundos” da 14ª Conferência Lusófona de Ciência Aberta, Natal Brasil, de 18 a 21 de setembro de 2023.
Creating a Digital Asset Register: our approach at University of Glasgow Archives & Special Collections
Creators: name: Yan, Emma
name: Konstantelos, Leo
Publisher: name: Zenodo
Year: 2024

description: The Digital Archive team at University of Glasgow Archives & Special Collections (ASC) have now completed work on establishing ASC’s born-digital asset register and wish to share with the digital preservation community our methods and lessons learned. In this presentation we share the practical processes that we used to identify and gather information on the born-digital assets in ASC’s collections and some of the questions that we asked ourselves to establish what we needed to record in the register.
title: CT-basierte 3D-Navigation transversaler Knochenkorridore der Segmente S1,2 und 3 für die sichere trans-sakrale Verschraubung des hinteren Beckenringes – Eine experimentelle Studie
Creators: name: Mendel, Thomas
name: Marintschev, Ivan
name: Radetzki, Florian
name: Noser, Hansrudi
name: Hofmann, Gunther O.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: trans-sakrale Verschraubung
subject: pelvis
subject: bilaterale Sakrumfraktur
subject: Navigation
subject: Knochenkorridor
subject: CT
subject: 610 Medical sciences; Medicine

description: Fragestellung: Die perkutane trans-sakrale Verschraubung (TSV) am hinteren Beckenring erlangt in den letzten Jahren zunehmende Bedeutung, insbesondere bei bilateralen Insuffizienzfrakturen des alten Patienten. Sie bietet den Vorteil hoher Stabilität bei geringer Invasivität, limitiert sich[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
Table S2 from Latitudinal cline of death-feigning behaviour in a beetle (Tribolium castaneum)
Creators: name: Matsumura, Kentarou
name: Miyatake, Takahisa
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60801 Animal Behaviour

description: AIC values of each GLM model.
title: Die BMP-Antagonisten Gremlin-1 und Noggin stimulieren die RANKL abhängige Osteoklastogenese
Creators: name: Hartmann, Eliza Sophie
name: Choy, John
name: Dolder, Silvia
name: Siebenrock, Klaus-Arno
name: Hofstetter, Willy
name: Klenke, Frank M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: BMP-2
subject: BMP Antagonisten
subject: Knochenresorption
subject: Noggin
subject: Gremlin
subject: Osteoklasten
subject: 610 Medical sciences; Medicine

description: Fragestellung: BMP-2 und BMP-7 werden zur Stimulation der Knochenheilung eingesetzt. Allerdings sind hohe BMP Konzentration nötig, um die gewünschten osteoinduktiven Effekte zu erzielen. Diese hohen Konzentrationen werden mit Nebenwirkungen wie Osteolysen und der Bildung von zystischen Knochenläsionen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
Security of differential quadrature phase shift quantum key distribution
Creators: name: Kawakami, Shun
name: Sasaki, Toshihiko
name: Koashi, Masato
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 81P45

description: One of the simplest methods for implementing quantum key distribution over fiber-optic communication is the Bennett-Brassard 1984 protocol with phase encoding (PE-BB84 protocol), in which the sender uses phase modulation over double pulses from a laser and the receiver uses a passive delayed interferometer. Using essentially the same setup and by regarding a train of many pulses as a single block, one can carry out the so-called differential quadrature phase shift (DQPS) protocol, which is a variant of differential phase shift (DPS) protocols. Here we prove the security of the DQPS protocol based on an adaptation of proof techniques for the BB84 protocol, which inherits the advantages arising from the simplicity of the protocol, such as accommodating the use of threshold detectors and simple off-line calibration methods for the light source. We show that the secure key rate of the DQPS protocol in the proof is eight thirds as high as the rate of the PE-BB84 protocol.
description: Citation of the Fig.1 in the text corrected
title: Ergebnisse nach Silikonölchirurgie bei Patienten mit persistierenden Maculaforamina
Creators: name: Grajewski, Luise
name: Carstens, J.
name: Krause, L.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Viele Studien haben bereits gezeigt, dass durch eine Pars-plana-Vitrektomie mit ILM- Peeling eine hohe Verschlussrate bei Maculaforamina erreicht wird. Dennoch persistieren einige Maculaforamina, so dass eine erneute Vitrektomie nötig ist. Patienten undMethode: In einer retrospektiven[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 24. Jahrestagung der Regionalgesellschaft der Augenärzte Sachsen-Anhalts und Thüringens
Charge and spin diffusion on the metallic side of the metal-insulator transition: a self-consistent approach
Creators: name: Wellens, Thomas
name: Jalabert, Rodolfo A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We develop a self-consistent theory describing the spin and spatial electron diffusion in the impurity band of doped semiconductors under the effect of a weak spin-orbit coupling. The resulting low-temperature spin-relaxation time and diffusion coefficient are calculated within different schemes of the self-consistent framework. The simplest of these schemes qualitatively reproduces previous phenomenological developments, while more elaborate calculations provide corrections that approach the values obtained in numerical simulations. The results are universal for zinc-blende semiconductors with electron conductance in the impurity band, and thus they are able to account for the measured spin-relaxation times of materials with very different physical parameters. From a general point of view, our theory opens a new perspective for describing the hopping dynamics in random quantum networks.
description: 22 pages, 13 figures
Exact solutions for logistic reaction-diffusion in biology
Creators: name: Broadbridge, P
name: Bradshaw-Hajek, BH
Publisher: name: arXiv
Year: 2016
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35K57, 35K55, 92D25, 92D99

description: Reaction-diffusion equations with a nonlinear source have been widely used to model various systems, with particular application to biology. Here, we provide a solution technique for these types of equations in $N$-dimensions. The nonclassical symmetry method leads to a single relationship between the nonlinear diffusion coefficient and the nonlinear reaction term; the subsequent solutions for the Kirchhoff variable are exponential in time (either growth or decay) and satisfy the linear Helmholtz equation in space. Example solutions are given in two dimensions for particular parameter sets for both quadratic and cubic reaction terms.
description: 18 pages, 6 figures
Lattice Thermal Conductivity of Organic-Inorganic Hybrid Perovskite CH3NH3PbI3
Creators: name: Qian, Xin
name: Gu, Xiaokun
name: Yang, Ronggui
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Great success has been achieved in improving the photovoltaic energy conversion efficiency of the organic-inorganic perovskite-based solar cells, but with very limited knowledge on the thermal transport in hybrid perovskites, which would affect the device lifetime and stability. Based on the potential developed from the density functional theory calculations, we studied the lattice thermal conductivity of the hybrid halide perovskite CH3NH3PbI3 using equilibrium molecular dynamics simulations. Temperature-dependent thermal conductivity is reported from 160 K to 400 K, which covers the tetragonal phase (160-330 K) and the pseudocubic phase (>330K). A very low thermal conductivity (0.50 W/mK) is found in the tetragonal phase at room temperature, whereas a much higher thermal conductivity is found in the pseudocubic phase (1.80 W/mK at 330 K). The low group velocity of acoustic phonons and the strong anharmonicity are found responsible for the relatively low thermal conductivity of the tetragonal CH3NH3PbI3.
title: Impact and Repercussions of Regional Industrial and Environmental Regulations on Austria ́s Steel Industry in the Context of an Inhomogenous Global Economy and Policy Suggestions for a Profitable Green Transition
Creators: name: Mitsche, Stella
Publisher: name: TU Wien
Year: 2024
Subjects: subject: Steel
subject: Industry
subject: Transition
subject: Policy
subject: Austria

description: A comprehensive analysis, aimed at understanding the evolution of the Austrian steel sector and thereby deriving future policy suggestions, suggests that the apparent decline in international competitiveness of the European steel sector can only be explained by incorporating the interconnection of many interdependent industrial and environmental regulatory acts as well as globally asymmetrical capital market exposure and various country specific factors. This decline has been particularly noticeable since the turn of the century, with Austria being disproportionally affected. Furthermore, multiple factors have been identified that are in support of policy intervention to assist the steel sector in its transition towards a decarbonized industry. Through an interdisciplinary approach, taking into account both technological feasibility and research on addressing market failures, policy recommendations for both the EU and Austria have been formulated.These conclusions stem from a comprehensive evaluation of various sources aggregated in a holistic assessment of the impact and repercussions of regional industrial and environmental regulations on an industry that is competing globally. This includes in-depth analyses on the EU-policy landscape and public policy research as well as country level macroeconomic data. Additionally, particular focus has been directed to an international comparison of present-day technology dominance and transitionary potential across countries and regions, in light of available steel production methods and their environmental impact. Concludingly it is suggested that EU-policy should focus on (1) promoting research,development and industrialization (R&D&I) focused on both carbon capture and storage/utilization (CCS/U) and carbon direct avoidance (CDA) technologies as well as knowledge sharing, (2) constructing and coupling hydrogen and renewable energy infrastructure, (3) building recycling markets, (4) ensuring green public procurement,(5) advancing financial incentive setting, (6) aligning global approximations and improving projections, (7) increasing public awareness and finally (8) creating a global level playing field through international agreements. Additionally for Austria (A) an even stronger focus on public awareness as well as (B) the introduction of earmarked CO2 taxes to finance (C) an increase in government R&D expenditure focused on advancing CCS/U technologies and recycling metallurgy and (D) national recycling infrastructure have been identified as additive policy measures.
Transport properties of bilayer graphene in a strong in-plane magnetic field
Creators: name: Van der Donck, M.
name: Peeters, F. M.
name: Van Duppen, B.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A strong in-plane magnetic field drastically alters the low-energy spectrum of bilayer graphene by separating the parabolic energy dispersion into two linear Dirac cones. The effect of this dramatic change on the transport properties strongly depends on the orientation of the in-plane magnetic field with respect to the propagation direction of the charge carriers and the angle at which they impinge on the electrostatic potentials. For magnetic fields oriented parallel to the potential boundaries an additional propagating mode that results from the splitting into Dirac cones enhances the transmission probability for charge carriers tunneling through the potentials and increases the corresponding conductance. Our results show that the chiral suppression of transmission at normal incidence is turned into a chiral enhancement when the magnetic field increases, thus indicating a transition from a bilayer to a monolayer-like system at normal incidence. Further, we find that the typical transmission resonances stemming from confinement in a potential barrier are shifted to higher energy and are eventually transformed into anti-resonances with increasing magnetic field. For magnetic fields oriented perpendicular to the potential boundaries we find a very pronounced transition from a bilayer system to two separated monolayer-like systems with Klein tunneling emerging at certain incident angles symmetric around 0, which also leaves a signature in the conductance. For both orientations of the magnetic field, the transmission probability is still correctly described by pseudospin conservation. Finally, to motivate the large in-plane magnetic field, we show that its energy spectrum can be mimicked by specific lattice deformations such as a relative shift of one of the layers. With this equivalence we introduce the notion of an in-plane pseudo-magnetic field.
description: 13 pages, 11 figures
Enhanced spin Seebeck effect signal due to spin-momentum locked topological surface states
Creators: name: Jiang, Zilong
name: Chang, Cui-Zu
name: Masir, Massoud Ramezani
name: Tang, Chi
name: Xu, Yadong
name: Moodera, Jagadeesh S.
name: MacDonald, Allan H.
name: Shi, Jing
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Spin-momentum locking in protected surface states enables efficient electrical detection of magnon decay at a magnetic-insulator/topological-insulator heterojunction. Here we demonstrate this property using the spin Seebeck effect, i.e. measuring the transverse thermoelectric response to a temperature gradient across a thin film of yttrium iron garnet, an insulating ferrimagnet, and forming a heterojunction with (BixSb1-x)2Te3, a topological insulator. The non-equilibrium magnon population established at the interface can decay in part by interactions of magnons with electrons near the Fermi energy of the topological insulator. When this decay channel is made active by tuning (BixSb1-x)2Te3 to a bulk insulator, a large electromotive force emerges in the direction perpendicular to the in-plane magnetization of yttrium iron garnet. The enhanced, tunable spin Seebeck effect which occurs when the Fermi level lies in the bulk gap offers unique advantages over the usual spin Seebeck effect in metals and therefore opens up exciting possibilities in spintronics.
Predator-prey model for the self-organisation of stochastic oscillators in dual populations
Creators: name: Moradi, Sara
name: Anderson, Johan
name: Gürcan, Özgür
Publisher: name: arXiv
Year: 2015
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: A predator-prey model of dual populations with stochastic oscillators is presented. A linear cross-coupling between the two populations is introduced following the coupling between the motions of a Wilberforce pendulum in two dimensions: one in the longitudinal and the other in torsional plain. Within each population a Kuramoto type competition between the phases is assumed. Thus, the synchronisation state of the whole system is controlled by these two types of competitions. The results of the numerical simulations show that by adding the linear cross-coupling interactions predator-prey oscillations between the two populations appear which results in self-regulation of the system by a transfer of synchrony between the two populations. The model represents several important features of the dynamical interplay between the drift wave and zonal flow turbulence in magnetically confined plasmas, and a novel interpretation of the coupled dynamics of drift wave-zonal flow turbulence using synchronisation of stochastic oscillator is discussed.
description: Accepted in Phys. Rev. E
Groups quasi-isometric to RAAG's
Creators: name: Huang, Jingyin
name: Kleiner, Bruce
Publisher: name: arXiv
Year: 2016
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We characterize groups quasi-isometric to a right-angled Artin group $G$ with finite outer automorphism group. In particular all such groups admit a geometric action on a $CAT(0)$ cube complex that has an equivariant "fibering" over the Davis building of $G$.
description: Minor corrections in the introduction, acknowledgement added
Edith Steins Stellung innerhalb der Phänomenologischen Bewegung
Creators: name: Sepp, Hans Rainer
Publisher: name: Edith Stein Jahrbuch
Year: 2025

description: 1641236132
description: Edith Stein Jahrbuch, V. 4 (1998): Edith Stein Jahrbuch, Band 4
Compartilhamento de dados de pesquisa em periódicos científicos: uma análise dos datapapers indexados na Scopus
Creators: name: Silveira, Crislaine Zurilda
name: Dias, Thiago Magela R.
name: Neubert, Patricia
Publisher: name: Zenodo
Year: 2023

description: Apresentação realizada na sessão “O meu Póster em 30 segundos” da 14ª Conferência Lusófona de Ciência Aberta, Natal Brasil, de 18 a 21 de setembro de 2023.
How Localized Z-Disc Damage Affects Force Generation and Gene Expression in Cardiomyocytes
Creators: name: Müller, Dominik
name: Donath, Sören
name: Brückner, Emanuel Georg
name: Biswanath Devadas, Santoshi
name: Daniel, Fiene
name: Gentemann, Lara
name: Zweigerdt, Robert
name: Heisterkamp, Alexander
name: Kalies, Stefan Michael Klaus
Publisher: name: Basel : MDPI
Year: 2021
Subjects: subject: Cardiomyocyte
subject: Femtosecond laser manipulation
subject: Traction forces
subject: Z-disc
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: The proper function of cardiomyocytes (CMs) is highly related to the Z-disc, which has a pivotal role in orchestrating the sarcomeric cytoskeletal function. To better understand Z-disc related cardiomyopathies, novel models of Z-disc damage have to be developed. Human pluripotent stem cell (hPSC)-derived CMs can serve as an in vitro model to better understand the sarcomeric cytoskeleton. A femtosecond laser system can be applied for localized and defined damage application within cells as single Z-discs can be removed. We have investigated the changes in force generation via traction force microscopy, and in gene expression after Z-disc manipulation in hPSC-derived CMs. We observed a significant weakening of force generation after removal of a Z-disc. However, no significant changes of the number of contractions after manipulation were detected. The stress related gene NF-kB was significantly upregulated. Additionally, α-actinin (ACTN2) and filamin-C (FLNc) were upregulated, pointing to remodeling of the Z-disc and the sarcomeric cytoskeleton. Ultimately, cardiac troponin I (TNNI3) and cardiac muscle troponin T (TNNT2) were significantly downregulated. Our results allow a better understanding of transcriptional coupling of Z-disc damage and the relation of damage to force generation and can therefore finally pave the way to novel therapies of sarcomeric disorders.
Generality of liquid precursor phases in gas diffusion-based calcium carbonate synthesis
Creators: name: Gindele, Maxim B.
name: Steingrube, Luisa Vanessa
name: Gebauer, Denis
Publisher: name: London : RSC
Year: 2021
Subjects: subject: Additives
subject: Calcium carbonate
subject: Carbonation
subject: Liquids
subject: Mineralogy
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: The ammonia diffusion method (ADM) is one of the most widely used strategies for the bioinspired synthesis of minerals. Herein, we present investigations of the mineralization mechanism using an advanced ADM to solve the limitations of the conventional ADM. This allows us to confirm the presence of liquid calcium carbonate precursor species in additive-free and polymer-stabilized gas diffusion systems, indicating that liquid-liquid phase separated species exhibit sufficient kinetic stability to be detected. Time-dependent experiments reveal the role of these precursor phases during the early stages of the crystallization process, demonstrating that liquid calcium carbonate mineral precursors play an important role in the precipitation pathway and must be generally considered for the interpretation of gas diffusion experiments, with and without additives. This discovery poses an important step in the understanding of how minerals are formed, highlighting that nonclassical mineralization processes must be considered for material synthesis. Last but not least, the advanced ADM may be useful for the exploration of the formation mechanism of other minerals than calcium carbonate, which are also of broad interest in the materials chemistry community.
Vestiges, part I & Nena and Anita vs. the powers of darkness, part I
Creators: name: Barros, Amelia
Publisher: name: No Publisher Supplied
Year: 2023

description: In Vestiges, the author examines the relationship between her childhood and adolescence in a strict, Pentecostal home and her young adult life and experiences. The author uses humor and compassion to navigate her experiences, from growing up as the daughter of first generation Colombian immigrants in an incredibly controlled religious environment to finding herself at Harvard and through to her current journey as a young mother and writer. Each chapter will be structured as a self-contained essay.In Nena and Anita vs. The Powers of Darkness, the author introduces us to Nena and Anita, twin sisters who are coming of age in a Pentecostal cult in an urban city. While the world (the 90s/00s) bustles around their home, they live in a sequestered, tightly controlled environment. Their church is particularly invested in the idea of spiritual warfare. The church’s obsession with purity and holiness culture also means that the girl’s budding sexuality and womanhood is perceived and treated as a threat. One Sunday morning, a visitor arrives in their church who changes everything. Not only does the visitor awaken the girls to their potential, sending them tumbling into their individual explorations of their own gender and sexuality, she also blesses/curses them with the gift of spiritual sight. Suddenly able to see the demons that lurk in their own home and church, the girls set out to exorcise their turf only to discover that the powers of darkness are not what they appear to be.
Model robust designs for survival trials
Creators: name: Konstantinou, Maria
name: Biedermann, Stefanie
name: Kimber, Alan
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: proportional hazards models
subject: Type-I censoring
subject: c-optimality
subject: D-optimality
subject: minimax optimal designs
subject: 310
subject: 330
subject: 620

description: The exponential-based proportional hazards model is often assumed in time- to-event experiments but may only approximately hold. We consider deviations in different neighbourhoods of this model that include other widely used paramet- ric proportional hazards models and we further assume that the data are subject to censoring. Minimax designs are then found explicitly based on criteria corre- sponding to classical c- and D-optimality. We provide analytical characterisations of optimal designs which, unlike optimal designs for related problems in the litera- ture, have finite support and thus avoid the issues of implementing a density-based design in practice. Finally, our designs are compared with the balanced design that is traditionally used in practice, and recommendations for practitioners are given.
description: Discussion Paper / SFB823;38, 2016
Student understanding of symmetry and Gauss's law of electricity
Creators: name: Singh, Chandralekha
Publisher: name: arXiv
Year: 2016
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: We investigate the difficulties that students in calculus-based introductory physics courses have with the concepts of symmetry, electric field, and electric flux which are important for applying Gauss's law. The determination of the electric field using Gauss's law requires determining the symmetry of a particular charge distribution and predicting the direction of the electric field everywhere if a high symmetry exists. Effective application of Gauss's law implicitly requires understanding the principle of superposition for electric fields. Helping students learn when Gauss's law can be readily applied to determine the strength of the electric field, and then helping them learn to determine the appropriate shape of Gaussian surfaces if sufficient symmetry exists, can help develop their reasoning and problem-solving skills. We administered free-response and multiple-choice questions and conducted interviews with individual students using a think-aloud protocol to elucidate the difficulties that students have with the concepts of symmetry, electric field, and electric flux. We also developed a multiple-choice test that targets these conceptual issues to obtain quantitative information about their difficulties and administered it to 541 students in the introductory calculus-based physics courses and to upper-level undergraduates in an electricity and magnetism course and to graduate students enrolled in a TA seminar course. We find that undergraduate students have many common difficulties with these concepts.
title: Multizentrische, doppelblinde, randomisierte Studie von Golimumab bei pädiatrischen Patienten mit aktiver pJIA trotz Methotrexat: Ergebnisse nach 48 Wochen
Creators: name: Brunner, Hermine
name: Horneff, Gerd
name: Ruperto, Nicola
name: Tzaribachev, Nikolay
name: Wouters, Carine
name: Chasnyk, Vyacheslav
name: Cuttica, Ruben
name: Keltsev, V.
name: Nasonov, Evgeny
name: Kingsbury, D.
name: Weller-Heinemann, Frank
name: Lovell, Daniel J.
name: Martini, Alberto
name: Panaviene, Violeta Vladislava
name: Abud Mendoza, Carlos
name: Reiff, Andreas
name: Alexeeva, Ekaterina
name: Joos, Rik
name: Bandeira, Márcia
name: Silverman, Earl
name: Van Royen-Kerkhof, Annet
name: Kim, Lilianne
name: Rubio-Perez, Nadina
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: juvenile idiopathische Arthritis
subject: doppelblind
subject: randomisiert
subject: Golimumab
subject: ACR30-Ansprechen
subject: klinische Remission
subject: 610 Medical sciences; Medicine

description: Einleitung: Beurteilung der Wirksamkeit und Sicherheit von Golimumab (GLM) bei pädiatrischen Patienten (2-17 Jahre) mit aktiver polyartikulärer juveniler idiopathischer Arthritis (pJIA) trotz mindestens 3-monatiger MTX-Therapie. Methoden: GO-KIDS war eine 3-phasige (P1: Wo0-16, P2: Wo16-48,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Review of Conformally Flat Approximation for Binary Neutron Star Initial Conditions
Creators: name: Suh, InSaeng
name: Mathews, Grant J.
name: Haywood, J. Reese
name: Lan, N. Q.
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The spatially conformally flat approximation (CFA) is a viable method to deduce initial conditions for the subsequent evolution of binary neutron stars employing the full Einstein equations. Here we review the status of the original formulation of the CFA for the general relativistic hydrodynamic initial conditions of binary neutron stars. We illustrate the stability of the conformally flat condition on the hydrodynamics by numerically evolving ~100 quasi-circular orbits. We illustrate the use of this approximation for orbiting neutron stars in the quasi-circular orbit approximation to demonstrate the equation of state dependence of these initial conditions and how they might affect the emergent gravitational wave frequency as the stars approach the innermost stable circular orbit.
description: 22 pages, 12 figures, revised as per referee recommendations
Non-Relativistic Chern-Simons Theories and Three-Dimensional Horava-Lifshitz Gravity
Creators: name: Hartong, Jelle
name: Lei, Yang
name: Obers, Niels A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show that certain three-dimensional Horava-Lifshitz gravity theories can be written as Chern-Simons gauge theories on various non-relativistic algebras. The algebras are specific extensions of the Bargmann, Newton-Hooke and Schroedinger algebra each of which has the Galilean algebra as a subalgebra. To show this we employ the fact that Horava-Lifshitz gravity corresponds to dynamical Newton-Cartan geometry. In particular, the extended Bargmann (Newton-Hooke) Chern-Simons theory corresponds to projectable Horava-Lifshitz gravity with a local U(1) gauge symmetry without (with) a cosmological constant. Moreover we identify an extended Schroedinger algebra containing 3 extra generators that are central with respect to the subalgebra of Galilean boosts, momenta and rotations, for which the Chern-Simons theory gives rise to a novel version of non-projectable conformal Horava-Lifshitz gravity that we refer to as Schroedinger gravity. This theory has a z=2 Lifshitz geometry as a vacuum solution and thus provides a new framework to study Lifshitz holography.
description: 9 pages, v2: references added and typos corrected
title: RheumaDATA: Vergleich von Schmerzen, Fatigue und Schlafstörungen bei 631 Patienten mit Rheumatoider Arthritis unter Biologikatherapie (Abatacept, Adalimumab, Etanercept und Tocilizumab)
Creators: name: Aries, Peer
name: Neuwirth, Joachim
name: Fliedner, Gerhard
name: Amberger, Christopher
name: Braunewell, Verena
name: Wagener, Peter
name: Kapelle, Andreas
name: Jacki, Swen Holger
name: Krüger, Klaus
name: Karger, Thomas
name: Stille, Carsten
name: Köhler, Lars
name: Hübner, Georg
name: Schoo, Ulrich
name: Wassenberg, Siegfried
name: Nüßlein, Hubert G.
name: Strothmeyer, Harald
name: Brandt-Jürgens, Jan
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Rheumatoide Arthritis
subject: Biologika
subject: Versorgungsforschung
subject: Schmerz
subject: PRO
subject: Fatigue
subject: 610 Medical sciences; Medicine

description: Einleitung: Entsprechend des IQWIG gibt es für jeden der zugelassenen biologischen Wirkstoffe einen Beleg, einen Hinweis oder mindestens Anhaltspunkte für einen Nutzen bei der Rheumatoiden Arthritis in Bezug auf mindestens ein Zielkriterium. Es wurde angemerkt, dass Langzeitdaten und ausreichende[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Global Analysis of the Source and Detector Nonstandard Interactions Using the Short Baseline Neutrino- and Antineutrino-Electron Scattering Data
Creators: name: Khan, Amir N.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We present a global analysis of the semileptonic and purely Leptonic nonuniversal and flavor-changing nonstandard neutrino interactions in all the known short-baseline neutrino- and antineutrino-electron scattering experiments. The nonstandard effects at the source and at the detector can be more transparent in these experiments because of the negligibly small ratio between the baselines and the neutrino energies, which is not enough for the neutrinos to oscillate, and thus can be sensitive to the new physics at the both ends. We use data from two electron-neutrino electron scattering experiments and six electron-antineutrino electron scattering experiments and combine them to find the best fits on the nonstandard parameters using the source-only, detector-only analyses, and then find the interplay between the two cases. The bounds obtained in some cases are stronger and new, in some cases comparable to the current ones, and in the other cases weaker. For instance, the bound obtained from the interplay between the source and detector nonstandard physics on the nonstandard parameter ε_{ee}^{udL} at the source is much stronger and is comparable with the indirect bound, but the bounds on the parameters ε_{μe}^{udL} and ε_{τe}^{udL} are weaker in this study in comparison with the indirect bounds. We also find a global fit on the standard weak mixing angle sinθ_{W}=0.249+-0.020 with 2% improvement in its precision in comparison with the previous studies.
description: 12 pages, 6 figures,5 tables, NSI study in elastic scatterings, published in Physical Review D
title: Elevated MMP-3 levels in early RA patients sera with Borrelia Antibodies
Creators: name: Jeremias, Patricia
name: Reuter, Sandra
name: Trinder, Peter
name: Schwarting, Andreas
name: Matthias, Torsten
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Rheumatoid Arthritis
subject: Borrelia
subject: infectious disease
subject: 610 Medical sciences; Medicine

description: Background: To investigate the influence of an infectious disease on Rheumatoid Arthritis (RA), patients from the ADAPTHERA study cohort were screened for antibodies to Borrelia antigens. Methods: 204 sera from early RA patients with disease duration < 6 months were screened using the following[for full text, please go to the a.m. URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Anti-Il 1 Therapy in patients with FMF-related amyloidosis living in Germany
Creators: name: Buhl, Birgit Maria
name: Blank, Norbert
name: Lorenz, Hanns-Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Amyloidosis
subject: 610 Medical sciences; Medicine

description: Background: Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease characterized by recurrent, self-limiting attacks of fever, and serositis. Renal amyloidosis is a serious complication of FMF that determines the prognosis. Patients with AA-Amyloidosis can be treated with[for full text, please go to the a.m. URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
title: Drei Fälle von anhaltenden Pseudarthrosen unter Therapie mit Leflunomid, reversibel nach Absetzen und Auswaschen des aktiven Metaboliten
Creators: name: Bauhammer, Jutta
name: Fiehn, Christoph
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Leflunomid
subject: Pseudarthrose
subject: rheumatoide Arthritis
subject: 610 Medical sciences; Medicine

description: Einleitung: Leflunomid wird als synthetisches DMARD in der Therapie der rheumatoiden Arthritis eingesetzt. Die häufigsten Nebenwirkungen umfassen gastrointestinale Unverträglichkeit, Leberwerterhöhung, Blutdruckanstieg, Blutbildveränderungen und periphere Neuropathie. Leflunomid [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Spinors and essential dimension
Creators: name: Garibaldi, Skip
name: Guralnick, Robert M.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Group Theory (math.GR)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 11E72 (Primary), 11E88, 20G10 (Secondary)

description: We prove that spin groups act generically freely on various spinor modules, in the sense of group schemes and in a way that does not depend on the characteristic of the base field. As a consequence, we extend the surprising calculation of the essential dimension of spin groups and half-spin groups in characteristic zero by Brosnan--Reichstein--Vistoli (Annals of Math., 2010) and Chernousov--Merkurjev (Algebra & Number Theory, 2014) to fields of characteristic different from 2.
description: v2 adds an appendix by Alexander Premet on generic stabilizer in HSpin_16 in characteristic 2
ERICC Working Paper_ERICC Research Agenda for Jordan
Creators: name: ERICC Consortium
name: Akogun, Oladele
name: Adesina, Adedoyin
name: Njobdi, Sani
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 390201
subject: Education policy
classificationCode: 390407
subject: Inclusive education

description: The Nigeria research agenda outlines the research direction based on the co-construction of evidence and sets out the co-creative principles for implementing the research agenda. The research themes that constitute the Nigeria research agenda were identified through consultations with key in-country stakeholders at the Federal level and in Borno, Adamawa, and Kaduna States.The stakeholders identified the priority research concerns around access, quality, continuity and coherence of education in conflict and crisis-affected contexts in Nigeria as the following, in sequence to be addressed: (1) policy, systems and sustainability; (2) teacher issues; (3) data; and (4) social and emotional learning. The stakeholder concerns were cross-checked with the literature for gaps in evidence. The research problems were then proposed as knowledge gaps where the concerns had not been addressed in the literature, where the research problems were the broad articulation of the stakeholder's concerns about an issue for which there is little or weak evidence in the literature that decision-makers can use for addressing it. The research problems in the research agenda will be further broken up into specific, policy-relevant research questions (and objectives) that will bridge current gaps in evidence for decision-making.The programme will leverage existing partnerships, build new ones and explore opportunities for funding evidence generation that the FCDO is unable to cover. Our primary method for evidence generation will continue to be a collaborative, co-constructive approach with participatory end-users. The end-users will participate in the research design, data collection, analysis, reflection, and evidence application for addressing the problems and gaps identified by the stakeholders.
title: Inverse Prothese bei chronischen Frakturfolgezuständen: Ergebnisse und Komplikationen bei 46 Patienten
Creators: name: Smith, Tomas
name: Kieckbusch, Max
name: Kaufmann, Melena
name: Pastor, Frederic
name: Ettinger, Max
name: Wellmann, Mathias
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Inverse Prothese
subject: Frakturfolge
subject: Notching
subject: Knochendefekt
subject: 610 Medical sciences; Medicine

description: Fragestellung: Die inverse Prothese ist zunehmend ein wichtiger Bestandteil des Behandlungskonzeptes bei chronischen Frakturfolgezuständen. Ergebnisrelevante prognostische Faktoren sind bisher noch unklar. Die Untersuchung zeigt unsere kurz- und mittelfristigen Ergebnisse und Komplikationen. [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)