cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Internet is creating Net-States
Creators: name: Koley, Gaurav
Publisher: name: Zenodo
Year: 2017
Subjects: net states, internet, social media

description: A nation-state is a geopolitical entity with the cultural entity of a nation, from which it aims to derive its political legitimacy to rule. A few key features of the nation-state are: A Sovereign Government Exclusive/Semi-exclusive Citizenship Territorial Integrity or Territorial Impermeability Nationalism as the core Philosophy The Web and Internet are two of the most significant technologies that are currently shaping our world. The increased Internet penetration and cheap access has spawned a whole lot of very popular web based services: search and advertising services like those offered by Google, social networks like Facebook, Twitter, Instagram; video stores like YouTube and others. An individual generates tremendous amount of data pertaining to his or her activities throughout the day, using these services. This data acts as a user’s identity or a “Data Double” on the Web with the service provider often being considered as the guarantor of the authenticity of the user. Our profiles at Facebook, Instagram, LinkedIn, Uber are such identities. And they are trusted albeit only to a certain extent. Also each of these Web Giants have their own governance style, characterised by their rules and regulations which are determined by both policy and the algorithms that run these platforms. Adding to that, the web is increasingly encouraging more cross-border exchanges of goods and services, allowing users and firms to bypass national borders. These phenomena raises the question of: Are these Web Giants a different kind of nation-state themselves? Is the Internet helping shape Net-States? To answer these questions, we use the theory of sociomateriality.
El espejo infiel: una aproximación al bandolero romántico y su reflejo en la literatura española
Creators: name: Cruz Casado, Antonio
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Bandolero; Romanticismo; Mito; Representación; Literatura Española

description: En contra de la teoría realista de la novela, que pretendía ser, en frase de Stendhal, un espejo que se pasea a lo largo de un camino, el reflejo del mundo de los bandoleros, de sus personajes y sus hazañas, ha sido en nuestra literatura harto infiel. Ajenas con frecuencia al mundo terrible de la delincuencia y del crimen, las obras literarias españolas, en sus concreciones genéricas de novela, teatro y poesía, nos han presentado una visión amable, edulcorada, muy mitificada en ocasiones, del bandido de la época romántica, personaje real, sin embargo, que trajo en jaque a las autoridades municipales y militares de la época.
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Talon noir: diagnóstico diferencial
Creators: name: Amaral, Brígida Correia
name: Machado, Susana
name: Selores, Manuela
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: Introdução: O talon noir é uma dermatose do desporto relacionada com o trauma. São máculas punctiformes castanho-azuladas ou negras, tipicamente localizadas no calcanhar, bilateralmente e simétricas, tradutoras de hemorragia intraepidérmica. São benignas, auto-limitadas e resolvem espontaneamente. Caso clínico: Os autores relatam o caso de um adolescente que apresenta máculas negras punctiformes com disposição linear na região posterior dos calcanhares, simetricamente. Sem queixas associadas. O doente usava sapatilhas rasas e apertadas, diariamente, para percursos a pé. Discussão: Apesar de ser uma dermatose típica de determinados desportos o talon noir não é exclusivo desta prática. Este é um caso interessante para alertar para o seu diagnóstico, sua benignidade e necessidade de exclusão de outras patologias que partilham a mesma topografia. Palavras-chave: Talon noir; petéquias do calcâneo; hemorragia intraepidérmica Background: Talon noir is a sport dermatosis related to trauma. It consists of black or bluish-brown punctate macules typically located at the heel, bilaterally and symmetrically, corresponding to intraepidermal hemorrhage. It is benign, self-limited and heals spontaneously. Case report: We report the case of a teenager who presents symmetric punctate black macules in a linear path on the back of the heels. No symptoms were related. The patient wore shallow and tight shoes daily for walking tours. Discussion: Despite being a typical sport dermatosis talon noir is not exclusive of its practice. This is an interesting case to alert for this diagnosis, its benignity and the need to exclude other diseases that share the same topography. Keywords: Talon noir; calcaneal petechiae; intraepidermal hemorrhage
description: Portuguese Journal of Pediatrics, Vol. 45 No. 4 (2014)
Sonnenfleckenzeichnung Nr. 24474.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.06.1974, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1974

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Imágenes del bandolero en algunas obras literarias españolas
Creators: name: Cardinale, Rosa
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Bandolero; Mito; Representación; Literatura Española; Siglos XVI-XX

description: Estudio de las representaciones del mito, de trasfondo real, del bandolero en obras de la literatura española, como el Quijote de Miguel de Cervantes, la autobiografía de Juan Caballero, la obra de Enrique Zúmel, de Antonio Espina y Fernando Martínez Laínez.
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Sonnenfleckenzeichnung Nr. 24495.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.07.1974, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1974

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Un instrumento de los intereses nacionalsocialistas durante la Guerra Civil española: el papel de la Sociedad Germano-Española de Berlín
Creators: name: Janué I Miret, Marició
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Historia; Relaciones culturales; Sociedad Germano-Española de Berlín; Alemania; España; Siglo XX; History; Cultural relations; German-Spanisch Society of Berlin; Germany; Spain; 20th Century

description: En este artículo, analizamos cómo la Sociedad Germano-Española de Berlín, fundada con la finalidad de fomentar las relaciones culturales entre Alemania y España, durante la Guerra Civil española subordinó su actuación a los propósitos proselitistas de las autoridades nacionalsocialistas. La Sociedad procuró atraer con gran variedad de medios a los círculos falangistas sensibles a la causa del nacionalsocialismo, actuando de mediadora entre éstos y las instancias estatales y del partido en Alemania.
Abstract
In this article we analyze how the German-Spanish Society of Berlin, founded to promote the cultural exchange between Germany and Spain, during de Spanish Civil War subjected its activities to the interests of the national socialist authorities. The Society used a variety of means trying to attract the falangist circles sensible to the cause of national socialism, and it acted as a mediator between these circles and the national socialist state and party authorities in Germany.
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Um caso de cianose atípico
Creators: name: Farinha Vilarinho Almeida, Ana Filipa
name: Sanmarful, Ines
name: Aguiar, Liza
name: Morais, Anabela
name: Lopes, Aldina Canteiro
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: Metahemoglobinémia é caracterizada por aumento dos níveis séricos de metahemoglobina originando hipoxémia e cianose. Pode ser hereditária ou adquirida após exposição a agentes oxidantes. Criança do sexo masculino, 4 anos, residente em meio rural, com instalação súbita de cianose labial e das extremidades marcada. Apresentava Saturação de oxigénio de 80% com pouco resposta ao oxigénio suplementar. Na gasimetria apresentava níveis elevados de metahemoglobina. Fez terapêutica com azul de metileno a 1% com boa evolução clinica e laboratorial. Referencia a contacto com água estagnada em local previamente exposto a fertilizantes químicos. Estudo enzimático confirmou défice ligeiro de citocromo b5 redutase. No caso clinico apresentado, uma criança com Metahemoglobinémia hereditária,previamente desconhecida, teve sintomatologia desencadeada por agente oxidante raro.
description: Portuguese Journal of Pediatrics, Vol. 45 No. 4 (2014)
Antero de Quental, Iberista: Iberianism as Organizing Principle and Evolving Intellectual Commitment
Creators: name: Newcomb, Robert Patrick
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Antero de Quental; Geração de 70; Iberianism; Portugal; 19th Century

description: In scholarship on Portugal’s Geração de 70 , Antero de Quental (1842-1891) is commonly remembered as the group’s intellectual guide or as a poet, with his sociopolitical prose unfortunately receiving less attention. This paper will propose iberianism – an intellectual current that advocates closer ties between Portugal and Spain – as an organizing principle of Quental’s prose, with his iberianist commitment evolving from an early advocacy of an Iberian federation through an interest in a common “peninsular race” and a defense of the beleaguered First Spanish Republic (1873-1874), to more fatalistic reflections on prospects for Spanish-Portuguese union. I will present Quental’s position in relation to earlier iberianists (J. F. Henriques Nogueira) and federalists (P.-J. Proudhon), and will analyze Quental’s Causas da decadência dos povos peninsulares (1871) as a transitional text in the author’s evolving iberianism.
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Alejandra Pizarnik después de 1968: la palabra instantánea y la “crueldad” poética
Creators: name: Depetris, Carolina
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Alejandra Pizarnik; Antonin Artaud; Poesía; Literatura argentina; Siglo XX; Poetry; Argentine Literature; 19th Century

description: El presente artículo sitúa a Alejandra Pizarnik en una línea de tradición poética moderna que promueve la aporía de buscar una palabra poética “pura” utilizando el código convencional de la lengua. En él se analizan dos modos en que Pizarnik practica esta búsqueda a partir de 1968: por medio de una alteración semiótica del signo lingüístico y por la cercanía que tiene este nuevo orden semántico con la práctica de la “crueldad”, entendida como una acción extrema dirigida a trascender y destruir los modos habituales del hacer poético. En el primer caso, repasaremos la estrecha relación que la propuesta de Pizarnik mantiene con la deconstrucción derrideana del logos; en el segundo, analizaremos la propuesta de esta poeta a la luz de las reflexiones sobre el teatro de Antonin Artaud.
Abstract
This article situates Alejandra Pizarnik in a line of a modern poetical tradition which promotes aporia in searching for a “pure” poetic word using the language conventional code. Two modes of practising this search by Pizarnik since 1968, are hereby analyzed: a) by means of a semiotic alteration of the linguistic sign; b) the nearness that this new semantic order has regarding the pratice of “cruelty”, understood as an extreme action directed to trascend and destroy the habitual modes of poetical doing. In the first case we shall review the close relationship that Pizarnik’s proposal maintains with the derridean deconstruction of the logos; in the second one, we shall analyze this poet’s proposal in the light of Antonin Artaud’s reflections on the theatre.
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Searching for potential drugs against SARS-CoV-2 through virtual screening on several molecular targets
Creators: name: Almeida, Joyce S. F. D.
name: Botelho, Fernanda D.
name: de Souza, Felipe R.
name: Santos, Marcelo C. dos
name: da Silva Goncalves, Arlan
name: Rodrigues, Rodrigo L. B.
name: Cardozo, Monique
name: Kitagawa, Daniel A. S.
name: Vieira, Leandro A.
name: Silva, Raphael S. F.
name: Cavalcante, Samir F. A.
name: da C. Bastos, Leonardo
name: de O. T. Nogueira, Mariana
name: de Santana, Priscila I. R.
name: de O. C. Brum, Juliana
name: Nepovimova, Eugenie
name: Kuca, Kamil
name: LaPlante, Steven R.
name: Galante, Erick B. F.
name: Franca, Tanos C. C.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: The acute respiratory syndrome caused by the SARS-CoV-2, known as COVID-19, has been ruthlessly tormenting the world population for more than six months. However, so far no effective drug or vaccine against this plague have emerged yet, despite the huge effort in course by researchers and pharmaceutical companies worldwide. Willing to contribute with this fight to defeat COVID-19, we performed a virtual screening study on a library containing Food and Drug Administration (FDA) approved drugs, in a search for molecules capable of hitting three main molecular targets of SARS-CoV-2 currently available in the Protein Data Bank (PDB). Our results were refined with further molecular dynamics (MD) simulations and MM-PBSA calculations and pointed to 7 multi-target hits which we propose here for experimental evaluation and repurposing as potential drugs against COVID-19. Additional rounds of docking, MD simulations and MM-PBSA calculations with remdesivir suggested that this compound can also work as a multi-target drug against SARS-CoV-2. Communicated by Ramaswamy H. Sarma
Intoxicações voluntárias em adolescentes - casuística de recorrência ao serviço de urgência de um hospital distrital
Creators: name: Serra Nunes, Isabel
name: Monteiro, Joana
name: Amorim, Joana
name: Jorge, Rita
name: Ferreira, Sofia
name: Costa, Miguel
name: Gomes, Lúcia
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: Introdução: O consumo abusivo de substâncias como álcool, medicamentos ou drogas ilícitas em adolescentes tem uma incidência cada vez maior em idades cada vez mais precoces. O álcool é a substância mais comummente implicada em intoxicações voluntárias em adolescentes, sendo que maioria destes consumos ocorre durante convívio social. As intoxicações são causa frequente de recorrência de adolescentes ao Serviço de Urgência (SU) e causa importante de morbilidade. O objetivo deste trabalho é caracterizar as intoxicações voluntárias em adolescentes que recorreram ao SU do Centro Hospitalar de Entre Douro e Vouga (CHEDV) entre 2009 e 2010. Material e Métodos: Estudo retrospetivo por análise de processos clínicos dos adolescentes (11-17 anos) que recorreram ao SU por intoxicação voluntária de qualquer tipo. Foram analisadas variáveis demográficas, tipo e motivo da intoxicação e sua orientação. Resultados/Discussão: As intoxicações voluntárias correspoderam a 0,54% de todos os adolescentes admitidos no SU. O estudo incluiu 139 adolescentes, 53,2% do sexo feminino com uma idade média de 15,7 anos. A afluência foi maior ao fim de semana e durante a madrugada (0h-6h). A intoxicação alcoólica foi a causa mais frequente (63,3%), seguida da medicamentosa e por drogas ilícitas. O convívio social foi o contexto mais frequente, sendo a ideação suicida rara (n=3). Problemas de ordem afetiva foram frequentemente referidos como motivo de consumo; antecedentes de patologia psiquiátrica e intoxicações anteriores foram descritos. Não foi encontrada diferença significativa entre os dois sexos exceto na intoxicação medicamentosa, mais frequente no sexo feminino. A intoxicação medicamentosa foi motivo de admissão em mais de um terço dos adolescentes, principalmente com recurso a benzodiazepinas e anti-piréticos/anti-inflamatórios. As intoxicações mistas (alcoólicas e medicamentosas) estiveram presentes em 3,6% dos casos condicionando maior risco de morbi-mortalidade. Foi realizado algum tipo de exame complementar na quase totalidade dos adolescentes (91,4%), sendo a fluidoterapia a terapêutica mais frequente. A grande maioria dos adolescentes teve alta para o domicílio, dois foram internados em Unidade de Cuidados Intensivos e 35,3% mantiveram seguimento em ambulatório. Conclusão: As intoxicações voluntárias são motivo frequente de recorrência ao SU, afetando idades cada vez mais precoces e condicionando importante morbilidade e utilização de recursos.
description: Portuguese Journal of Pediatrics, Vol. 45 No. 4 (2014)
Sonnenfleckenzeichnung Nr. 24530.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.09.1974, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1974

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Cuidados não parentais a crianças com idade inferior a três anos: revisão baseada na evidência
Creators: name: Cardoso, Vítor Bruno Portela Lopes
name: Mendes, Paula Fernandes
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: Introdução: A rápida e massiva ingressão da mulher no mercado de trabalho associou-se a um aumento na dependência de cuidados não parentais (CNP) das crianças, em idades cada vez mais jovens. Objetivo: Rever a evidência sobre o efeito no desenvolvimento cognitivo e da linguagem dos CNP a crianças com menos de 3 anos de idade. Métodos: Foi realizada uma pesquisa de estudos originais, normas de orientação clínica, revisões sistemáticas e meta-análises, nas fontes de dados: National Guideline Clearinghouse, Guidelines Finder, Canadian Medical Association Practice Guidelines, Cochrane, DARE, Bandolier, Medline, PsycInfo e Índex de Revistas Médicas Portuguesas, publicados entre 1975 e 2012, nas línguas portuguesa, inglesa, francesa e espanhola e utilizando os termos MeSH: child day care center, infant, cognition e language development. Foi utilizada a escala Strength of Recommendation Taxonomy (SORT) para atribuição dos níveis de evidência (NE). Resultados: Obtiveram-se 89 artigos, tendo 3 estudos prospectivos preenchido os critérios de inclusão. O Early Child Care Research Network concluiu que os CNP numa creche associaram-se a melhores resultados no desenvolvimento cognitivo e da linguagem do que nos outros tipos de cuidados, como no domicílio (NE1). Segundo Broberg, mais tempo sob CNP conferia níveis mais elevados nos testes de capacidade verbal e matemática aos 8 anos (NE2) e segundo Andersson, melhor desempenho escolar aos 8 e 13 anos e melhor adaptação escolar aos 8 anos (NE2). Discussão: Os CNP até aos 3 anos poderão ser benéficos a nível do desenvolvimento cognitivo e da linguagem, traduzindo-se possivelmente num melhor desempenho escolar (SORT B).
description: Portuguese Journal of Pediatrics, Vol. 45 No. 4 (2014)
Virtual repurposing of ursodeoxycholate and chenodeoxycholate as lead candidates against SARS-Cov2-Envelope protein: A molecular dynamics investigation
Creators: name: Yadav, Reena
name: Choudhury, Chinmayee
name: Kumar, Yashwant
name: Bhatia, Alka
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Drug repurposing is an apt choice to combat the currently prevailing global threat of COVID-19, caused by SARS-Cov2in absence of any specific medication/vaccine. The present work employs state of art computational methods like homology modelling, molecular docking and molecular dynamics simulations to evaluate the potential of two widely used surfactant drugs namely chenodeoxycholate(CDC) and ursodeoxycholate (UDC), to bind to the envelope protein of SARS-Cov2(SARS-Cov2-E).The monomeric unit of SARS-Cov2-E was modelled from a close homologue (>90% sequence identity) and a pentameric assembly was modelled using symmetric docking, followed by energy minimization in a DPPC membrane environment. The minimized structure was used to generate best scoring SARS-Cov2-E–CDC/UDC complexes through blind docking. These complexes were subjected to 230 ns molecular dynamics simulations in triplicates in a DPPC membrane environment. Comparative analyses of structural properties and molecular interaction profiles from the MD trajectories revealed that, both CDC and UDC could stably bind to SARS-Cov2-E through H-bonds, water-bridges and hydrophobic contacts with the transmembrane-channelresidues.T30 was observed to be a key residue for CDC/UDC binding. CDC/UDC binding affected the H-bonding pattern between adjacent monomeric chains, slackening the compact transmembrane region of SARS-Cov2-E. Additionally, the polar functional groups of CDC/UDC facilitated entry of a large number of water molecules into the channel. These observations suggest CDC/UDC as potential candidates to hinder the survival of SARS-Cov2 by disrupting the structure of SARS-Cov2-E and facilitating the entry of solvents/polar inhibitors inside the viral cell. Communicated by Ramaswamy H. Sarma
La verdad de la ficción: bandolerismo, historia, literatura, sociedad. Presentación
Creators: name: López De Abiada, José Manuel
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Bandolerismo; España; Representación

description: Presentación al dossier
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Una aproximación al bandolerismo en España
Creators: name: Rodríguez Martín, José Antonio
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Bandolerismo; España; Sociedad; Antropología; Representaciones; Mitos

description: Sería más que pretencioso intentar dar una visión precisa del fenómeno del bandolerismo en España en apenas una veintena de páginas; de ahí el término aproximación que incluyo en el título y, por otra parte, las dudas que surgen al tratar de globalizar el asunto en su ámbito correspondiente. Es decir, ¿sería correcto hablar de un bandolerismo español? ¿Tendría éste unas características propias que permitirían fácilmente diferenciarlo de otros bandolerismos extranjeros? O, por el contrario, en España existieron distintos tipos de bandolerismo, con diferencias específicas, según las regiones en las que se desarrollaron, que harían imposible hablar de manera genérica de un bandolerismo español. Se hace necesario como punto de partida definir el término bandolerismo, asociado a otros dos vocablos claves en la cuestión: bandido y bandolero.
description: IBEROAMERICANA, Vol. 8, Núm. 31 (2008)
Shedding light on the bimolecular interactions of Cafaminol and human serum albumin: spectroscopic characterization and in-silico investigation
Creators: name: Parvizi, Negar
name: Mohammad-Aghaie, Delara
name: Rad, Mohammad Navid Soltani
name: Behrouz, Somayeh
name: Alavianmehr, Mohamad Mehdi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Cafaminol, also known as methylcoffanolamine, is a vasoconstrictor and anticatarrhal of the methylxanthine family, which is used as a nasal decongestant. This study aimed to investigate the interaction mechanisms of human serum albumin (HSA) with Cafaminol, through several spectroscopic (fluorescence quenching, UV-visible absorption, and circular dichroism (CD) spectroscopies) and molecular modeling techniques. Stern-Volmer plots were employed to specify the fluorescence quenching mechanism, while the simulation methods were utilized to deduce the approximate binding position of Cafaminol on HSA. On the other hand, thermodynamic parameters, enthalpy and entropy changes, were determined to be, respectively, −105.88 (kJ mol−1) and −282.34 (J mol−1 K−1), using the Van't Hoff equation and analyzed later to specify the main acting forces between Cafaminol and HSA. Overall results revealed the binding of Cafaminol to the site I of HSA, as a result of an enthalpy-driven process, mainly through the van der Waals and hydrogen bonding interactions. Static quenching mechanism was found to be responsible for the fluorescence quenching of HSA in the Cafaminol presence, while the number of binding sites and apparent binding constant were measured accordingly. Docking results proposed that Cafaminol and HSA interact with a binding free energy (ΔG) of −6.5 kcal mol−1 Communicated by Ramaswamy H. Sarma
A importância da interligação hospitalar: a experiência Hospital de Faro e IPO de Lisboa
Creators: name: Pereira, Ana Sousa
name: Carrasqueira, Dolores
name: Chagas, Sandra
name: Paiva, Helena
name: Pedroso, Elsa
name: Pereira, Filomena
name: Lacerda, Ana
name: Rocha, Elsa
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: A patologia oncológica é pouco frequente na criança, mas o seu diagnóstico e tratamento acarretam grande impacto familiar. As Unidades de Oncologia Pediátrica concentram os cuidados especializados de uma grande área geográfica. Para assegurar o suporte clínico e psicossocial é essencial estabelecer uma interligação e comunicação eficazes entre os técnicos de saúde locais e a Unidade de Oncologia Pediátrica (UOP). Este trabalho teve como objectivo caracterizar a população pediátrica oncológica da área de referência do Hospital de Faro entre Janeiro de 2005 e Dezembro de 2010, analisando a experiência de colaboração com o IPO de Lisboa. Procedeu-se à análise longitudinal retrospectiva por consulta dos processos clínicos de Hospital de Dia e Enfermaria, e do Sistema Informático de Apoio ao Médico. Analisaram-se 46 processos (54% sexo masculino; idade média no diagnóstico 6.3 anos). Os tumores mais frequentes foram Leucemia Linfoblástica Aguda (n=10) e Neuroblastoma (n=8). A localidade com maior número de casos foi Olhão (n=13); 79% dos pais de nacionalidade portuguesa. Registaram-se 1263 episódios em Hospital de Dia (média 27 episódios/criança), para avaliação clínica, laboratorial e realização de múltiplos procedimentos. Verificaram-se, simultaneamente, na Enfermaria do Serviço de Pediatria, 83 internamentos, sobretudo por neutropénia febril (41%). Podemos concluir que a existência do Hospital de Dia de Pediatria no Hospital de Faro veio facilitar a articulação com o IPOLFG. Numa perspectiva integrada de complementaridade de recursos, criaram-se condições para a padronização de procedimentos, melhorou-se a acessibilidade e eficiência dos cuidados prestados, com impacto positivo clínico, económico e social e consequentes ganhos em saúde
description: Portuguese Journal of Pediatrics, Vol. 45 No. 4 (2014)
Molecular mechanism of inhibition of COVID-19 main protease by β-adrenoceptor agonists and adenosine deaminase inhibitors using in silico methods
Creators: name: Venugopal, Pushyaraga P.
name: Chakraborty, Debashree
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Novel coronavirus (COVID-19) responsible for viral pneumonia which emerged in late 2019 has badly affected the world. No clinically proven drugs are available yet as the targeted therapeutic agents for the treatment of this disease. The viral main protease which helps in replication and transcription inside the host can be an effective drug target. In the present study, we aimed to discover the potential of β-adrenoceptor agonists and adenosine deaminase inhibitors which are used in asthma and cancer/inflammatory disorders, respectively, as repurposing drugs against protease inhibitor by ligand-based and structure-based virtual screening using COVID-19 protease-N3 complex. The AARRR pharmacophore model was used to screen a set of 22,621 molecules to obtain hits, which were subjected to high-throughput virtual screening. Extra precision docking identified four top-scored molecules such as +/−-fenoterol, FR236913 and FR230513 with lower binding energy from both categories. Docking identified three major hydrogen bonds with Gly143, Glu166 and Gln189 residues. 100 ns MD simulation was performed for four top-scored molecules to analyze the stability, molecular mechanism and energy requirements. MM/PBSA energy calculation suggested that van der Waals and electrostatic energy components are the main reasons for the stability of complexes. Water-mediated hydrogen bonds between protein-ligand and flexibility of the ligand are found to be responsible for providing extra stability to the complexes. The insights gained from this combinatorial approach can be used to design more potent and bio-available protease inhibitors against novel coronavirus. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 24475.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.07.1974, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1974

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Soñar con el futuro. Proyectos inmigratorios para la Patagonia argentina en Teodoro Alemann y Roberto J. Payró
Creators: name: Valko, Jennifer M.
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Periodismo; Inmigración; Argentina; Alemania; Siglo XIX; Journalism; Immigration; Germany; Nineteenth Century

description: Considerando los estudios recientes sobre viajes periodísticos y la construcción de la nación argentina, este artículo examina el perfil de un reportero menos estudiado, el periodista inmigrante. Se analizan dos crónicas de viajes sobre la Patagonia publicadas en Buenos Aires en 1898: Ein Ausflug nach dem Chubut-Territorium  [Una excursión al territorio de Chubut] del periodista suizo Teodoro Alemann, publicada en el periódico alemán Argentinisches Tageblatt  [Diario Argentino], y La australia argentina del argentino Roberto J. Payró aparecida en La Nación.  La narración del viaje a la Patagonia en ambas crónicas es interrumpida en un momento clave por el relato de un sueño sobre el porvenir de la zona. Este trabajo demuestra que dicha digresión onírica revela intereses políticos y económicos opuestos al proyecto oficial argentino de desarrollo de la región, el papel de los inmigrantes y su relación con potencias europeas.

Abstract
Taking into account recent studies on journalistic travel and Argentine nation building, this article examines the profile of a type of reporter that has been studied to a lesser degree, the immigrant journalist. It analyzes two travel chronicles about Patagonia published in Buenos Aires in 1898: Ein Ausflug nach dem Chubut-Territorium [An Excursion to the Chubut Territory] by Swiss journalist Theodor Alemann, published in the German-language newspaper Argentinisches Tageblatt [Argentine Daily], and La australia argentina, by Roberto J. Payró which appeared in La Nación. In both chronicles the narration of the trip to Patagonia is interrupted at a key moment by the telling of a dream regarding the future of the region. This essay demonstrates that these oneiric digressions reveal political and economic interests contrary to the official Argentine plans for the development of the region, the role of immigrants and their relationship with European powers.
description: IBEROAMERICANA, Vol. 8, Núm. 30 (2008)
Physiological factors affecting chicken ovarian function and the potential mitigation strategies - A critical review
Creators: name: Tevanu Berthier
name: Yue Zhang
name: Yongsheng Li
name: Shuang Li
name: Banggui Song
name: Fangxiong Shi
name: Guofeng Han
name: Quanwei Wei
Publisher: name: Zenodo
Year: 2024
Subjects: Ovarian function, Chicken, physiological factor, production loss, mitigation strategy.

description: Abstract: The poultry industry has performed a leading role worldwide, and reproductive efficiency is an important economic factor in poultry production. However, various physiological factors adversely affect the ovarian function of laying hens, such as environmental, hormonal, genetic, disease, and immune factors.  Environmental stress impairs hen’s health by reducing feed intake, body weight, egg production and follicle development rate. Nutritional toxicity, excessive nutrient absorption, and obesity are serious issues in poultry production. Extensive research has linked overfeeding to chicken ovarian dysfunction, including oviduct inflammation, prolapse, erratic oviposition, and defective egg syndrome. Various poultry diseases such as Newcastle disease, fowl pox, and coccidiosis cause huge production losses. The Newcastle disease causes the highest percentage of mortality in both domestic and wild birds, resulting in substantial economic losses. Hence, managing drinking water sanitation, chicken body weight, flock uniformity, and reproductive function (follicular growth and maturation) can decrease the risk of stress-associated metabolic diseases. To increase the sustainability of the egg industry, the current review paper's objective is to explore the physiological aspects that have a detrimental impact on chicken ovarian function and their potential mitigation techniques.
Sonnenfleckenzeichnung Nr. 24563.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.10.1974, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1974

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Meningite assética associada à terapêutica com imunoglobulina endovenosa
Creators: name: Francisco, Telma
name: Lito, David
name: Girbal, Inês
name: Cunha, Florbela
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: A meningite asséptica pode ser uma complicação da terapêutica com imunoglobulina endovenosa. Apresentamos o caso de um rapaz, 4 anos, previamente saudável, internado por Púrpura Trombocitopénica Imune. Recebeu duas doses de imunoglobulina endovenosa. Quatro horas após a última administração iniciou síndrome meníngea. O líquido cefalorraquidiano revelou 500células/μL (predomínio neutrófilos), com bioquímica normal. Os exames bacteriológico e virulógico foram negativos. Ficou assintomático após 48h. Dada a ausência de outro factor etiológico e a relação temporal com a administração da imunoglobulina, admitimos tratar-se de uma meningite pós imunoglobulina endovenosa. Esta terapêutica pode causar cefaleias, febre e vómitos; contudo, habitualmente não se efectua punção lombar, estando esta complicação eventualmente subdiagnosticada.
description: Portuguese Journal of Pediatrics, Vol. 45 No. 3 (2014)
Sustainable Transformation of South Africa’s Agri-food System through Statutory Incentives: Evidence from Agricultural Industries
Creators: name: Myeki, LW
name: Nyhodo, B,
name: Mpyana, BM
name: Nakana, E
name: Yeki, N
name: Makhele, B
name: Smith, R
name: Chokoe, C
name: Ntombela, S
name: Mazibuko, N
name: Ngqangweni, S
Publisher: name: Unknown
Year: 2024
Subjects: Dairy Production/Industries
Institutional and Behavioral Economics

description: Transformation towards sustainable agri-food systems remains a hot topic due to the pressing need to attain sustainable development-related goals. The paper was designed to uncover the impact of statutory incentives on sustainable transformation of agri-food system in South Africa. We apply behavioural economic method, comprising of psychological attributes and economic- related measures on cross-sectional data obtained from farmers supported through statutory levies and trust funds collected and administered by 14 agricultural industries. The results show that participants are appreciative, socially pressured, and possess high perception of their ability to perform sustainable transformation. Hence, we found a positive endorsement for the impact of statutory incentives on sustainable transformation in agri-food system, regardless of gender distinction. This endorsement is high among older farmers compared to their younger counterparts, and also high in horticulture and field crops compared to livestock sector. Finally, results reveal that sustainable transformation is consistently determined by attitudes, present time, and agreeableness. We conclude that multidisciplinary approach avails more insights on the research agenda for transformation of agri-food systems and tends to yield to better policy options for selection of beneficiaries towards driving sustainable transformation of agri-food system within agricultural industries in South Africa.
Gastroenterite aguda por Salmonella não tifóide em crianças: revisão de dez anos
Creators: name: Pignatelli, Diana
name: Leal, Ema
name: Lito, David
name: Damaso, Catarina
name: Rodrigues, Margarida
name: Cunha, Florbela
Publisher: name: Portuguese Journal of Pediatrics
Year: 2014

description: Introdução e Objectivos: A Salmonella não tifóide é o agente mais frequente das toxi-infecções alimentares nos países desenvolvidos. Em Portugal são notificados em média 450 casos por ano, 80% dos quais em crianças. O presente estudo tem como objectivo a caracterização dos casos de gastroenterite aguda por Salmonella numa população pediátrica. Material e Métodos: Revisão casuística dos casos confirmados por coprocultura, internados num Hospital de Nível II, na região de Lisboa e Vale do Tejo, entre 1999 e 2008. Análise estatística no programa SPSS® v16.0, com aplicação do teste de Spearman e significância estatística para p<0,05. Resultados: Identificaram-se 213 internamentos. A mediana anual foi de 21 internamentos, 39% ocorrendo no Verão. A mediana das idades foi de 4,2 anos, com doze casos em lactentes até aos três meses. Houve um predomínio no sexo masculino (57%). A mediana do total de leucócitos foi de 9300 /mL e da Proteína C Reactiva de 8,8 mg/dL, não se relacionando com a ocorrência de bacteriémia. A duração média do internamento foi de 5,2 dias. As principais complicações foram desidratação (117/213), bacteriémia (8/213), convulsão febril (6/213), síndrome de Mallory-Weiss (5/213) e apendicite aguda (3/213). Os serotipos mais isolados foram: S. Enteritidis (76%), S. Typhimurium (19%), outros (5%): S. O4,5:i-, S. Derby, S. Hayfa, S. Menden, S. Rissen. Encontraram-se 27% de resistências à ampicilina e 15% ao trimetoprim-sulfametoxazol, sem resistências ao ceftriaxone. Conclusão: Nos dez anos estudados o número de casos manteve-se elevado, com morbilidade relevante e resistências significativas aos antibióticos de primeira linha.
description: Portuguese Journal of Pediatrics, Vol. 45 No. 3 (2014)
El personaje femenino en los cuentos de Juan Rulfo
Creators: name: Ramírez, Hugo Hernán
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Juan Rulfo; Cuento; Mujeres; México; Siglo XX; Story; Women; Mexico; 19th. Century

description: Una de las características de la prosa de Rulfo es un laconismo que permite construir personajes a partir de pinceladas que aprovechan el potencial evocativo del lenguaje, eliminan las digresiones y omiten las descripciones. En Rulfo los personajes femeninos desbordan los estereotipos de virgen o madre y se instalan en el centro de cada relato; aun sin voz, ellos disparan la acción de varios relatos, son definitivos en la resolución de los conflictos, favorecen el lucimiento lírico del narrador e irradian una vitalidad cuyos signos fundamentales son la belleza física, el erotismo y la ternura.
Abstract
One characteristic of Rulfo’s prose is a laconism that allows to construct characters with brushstrokes that take advantage of potential evocative language; they eliminate digressions and omit descriptions. In Rulfo the feminine characters exceed the stereotypes of virgin or mother and are installed in the center of short stories. Even without a voice, they trigger the action of several stories, are definitive in the resolution of conflicts, favor the lyric splendor of the narrator, and radiate a vitality marked by signs of physical beauty, eroticism and tenderness.
description: IBEROAMERICANA, Vol. 8, Núm. 30 (2008)
Literatura y trastorno o la alegoría de la narración en Javier Marías
Creators: name: Grohmann, Alexis
Publisher: name: Ibero-Amerikanisches Institut (Berlin)
Year: 2014
Subjects: Javier Marías; Novela; Alegoría; España; Siglos XX-XX; Novel; Allegory; Spain; 19th-20th Century

description: La mayoría de las novelas de Javier Marías consisten esencialmente en relatos de trastornos padecidos por sendos narradores y de los efectos de la perturbación sobre las vidas y mentes de éstos. Este fenómeno extendido invita a una lectura alegórica, la alegoría de una anomalía que padece el propio escritor (en el proceso de creación), porque tanto en el caso de los narradores como en el del autor el trastorno contribuye en muy gran medida a la creación de la historia narrada, hasta tal punto que se podría sostener que en la narrativa de Marías la creación literaria equivale a un trastorno.
Abstract
The majority of Javier Marías’s novels are, in effect, stories of a mental disorder experienced by each of the narrators and of the effects of this disturbance on their lives and minds. This prominent phenomenon invites an allegorical reading, namely that of an anomaly the writer himself is experiencing (during the creative process), because both in the case of the narrators and in that of the author the disorder contributes to a very considerable extent to the creation of the story narrated, to such a degree that one could argue that in Marías’s prose narratives literary creation corresponds to mental disturbance.
description: IBEROAMERICANA, Vol. 8, Núm. 30 (2008)
Sonnenfleckenzeichnung Nr. 24502.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.08.1974, erstellt von Johann Dürst
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1974

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel