cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Footstep Adjustment for Biped Push Recovery on Slippery Surfaces
Creators: name: Ghorbani, Erfan
name: Karimpour, Hossein
name: Pasandi, Venus
name: Keshmiri, Mehdi
Publisher: name: arXiv
Year: 2021
Subjects: subject: Robotics (cs.RO)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Despite extensive studies on motion stabilization of bipeds, they still suffer from the lack of disturbance coping capability on slippery surfaces. In this paper, a novel controller for stabilizing a bipedal motion in its sagittal plane is developed with regard to the surface friction limitations. By taking into account the physical limitation of the surface in the stabilization trend, a more advanced level of reliability is achieved that provides higher functionalities such as push recovery on low-friction surfaces and prevents the stabilizer from overreacting. The discrete event-based strategy consists of modifying the step length and time period at the beginning of each footstep in order to reestablish stability necessary conditions while taking into account the surface friction limitation as a constraint to prevent slippage. Adjusting footsteps to prevent slippage in confronting external disturbances is perceived as a novel strategy for keeping stability, quite similar to human reaction. The developed methodology consists of rough closed-form solutions utilizing elementary math operations for obtaining the control inputs, allowing to reach a balance between convergence and computational cost, which is quite suitable for real-time operations even with modest computational hardware. Several numerical simulations, including push recovery and switching between different gates on low-friction surfaces, are performed to demonstrate the effectiveness of the proposed controller. In correlation with human-gait experience, the results also reveal some physical aspects favoring stability and the fact of switching between gaits to reduce the risk of falling in confronting different conditions.
description: for associated simulation video, see https://youtu.be/BWzUgHGdl3I
A magic lantern show demonstrating scientific truths, Imagineers in Circus and Science: Scientific Knowledge and Creative Imagination
Creators: name: Jolly, Martyn
name: DeCourcy, Elisa
name: Hunter, Alexander
name: McMahon, Paul
Publisher: name: Australian National University
Year: 2018

description: A magic lantern show demonstrating scientific truths, developed as part of the ARC DP16 Heritage in the Limelight: The Magic lantern in Australia and the World, with Dr Elisa deCourcy and Paul mCMahon, ANU, and Ben Keogh, for the Imagineers in Circus and Science: Scientific Knowledge and Creative Imagination conference, Australian National University, 3-5 April, and for the Mount Stromlo Open Night, Mount Stromlo Observatory, 20 April.
Multicore Quantum Computing
Creators: name: Jnane, Hamza
name: Undseth, Brennan
name: Cai, Zhenyu
name: Benjamin, Simon C
name: Koczor, Bálint
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Any architecture for practical quantum computing must be scalable. An attractive approach is to create multiple cores, computing regions of fixed size that are well-spaced but interlinked with communication channels. This exploded architecture can relax the demands associated with a single monolithic device: the complexity of control, cooling and power infrastructure as well as the difficulties of cross-talk suppression and near-perfect component yield. Here we explore interlinked multicore architectures through analytic and numerical modelling. While elements of our analysis are relevant to diverse platforms, our focus is on semiconductor electron spin systems in which numerous cores may exist on a single chip. We model shuttling and microwave-based interlinks and estimate the achievable fidelities, finding values that are encouraging but markedly inferior to intra-core operations. We therefore introduce optimsed entanglement purification to enable high-fidelity communication, finding that $99.5\%$ is a very realistic goal. We then assess the prospects for quantum advantage using such devices in the NISQ-era and beyond: we simulate recently proposed exponentially-powerful error mitigation schemes in the multicore environment and conclude that these techniques impressively suppress imperfections in both the inter- and intra-core operations.
description: 26 pages, 16 Figures
Variational Tempering
Creators: name: Mandt, Stephan
name: McInerney, James
name: Abrol, Farhan
name: Ranganath, Rajesh
name: Blei, David
Publisher: name: arXiv
Year: 2014
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Variational inference (VI) combined with data subsampling enables approximate posterior inference over large data sets, but suffers from poor local optima. We first formulate a deterministic annealing approach for the generic class of conditionally conjugate exponential family models. This approach uses a decreasing temperature parameter which deterministically deforms the objective during the course of the optimization. A well-known drawback to this annealing approach is the choice of the cooling schedule. We therefore introduce variational tempering, a variational algorithm that introduces a temperature latent variable to the model. In contrast to related work in the Markov chain Monte Carlo literature, this algorithm results in adaptive annealing schedules. Lastly, we develop local variational tempering, which assigns a latent temperature to each data point; this allows for dynamic annealing that varies across data. Compared to the traditional VI, all proposed approaches find improved predictive likelihoods on held-out data.
description: published version, 8 pages, 4 figures
Deep Q-learning: a robust control approach
Creators: name: Varga, Balazs
name: Kulcsar, Balazs
name: Chehreghani, Morteza Haghir
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: In this paper, we place deep Q-learning into a control-oriented perspective and study its learning dynamics with well-established techniques from robust control. We formulate an uncertain linear time-invariant model by means of the neural tangent kernel to describe learning. We show the instability of learning and analyze the agent's behavior in frequency-domain. Then, we ensure convergence via robust controllers acting as dynamical rewards in the loss function. We synthesize three controllers: state-feedback gain scheduling H2, dynamic Hinf, and constant gain Hinf controllers. Setting up the learning agent with a control-oriented tuning methodology is more transparent and has well-established literature compared to the heuristics in reinforcement learning. In addition, our approach does not use a target network and randomized replay memory. The role of the target network is overtaken by the control input, which also exploits the temporal dependency of samples (opposed to a randomized memory buffer). Numerical simulations in different OpenAI Gym environments suggest that the Hinf controlled learning performs slightly better than Double deep Q-learning.
Assessing resistance to Septoria tritici blotch in a multi-parent advanced generation inter-cross (MAGIC) population of wheat (Triticum aestivum L.)
Creators: name: Folarin, Oladapo
name: Adegboye, Isaac
name: Veli, Ayse
name: Mikaberidze, Alexey
Publisher: name: Zenodo
Year: 2023

description: Septoria tritici blotch (STB) caused by Zymoseptoria tritici, is the most economically important fungal disease of wheat in the UK(1). STB has been estimated to cause an annual economic loss of £100-200M in the UK and costs wheat growers an expenditure of about £140-280M per year on fungicides. STB is majorly controlled by using fungicides and resistant cultivars. However, the pathogen rapidly adapts to fungicides and resistant varieties which makes it difficult to control. Thus, there is constant effort to develop new sources of resistance against Z. tritici, one of which is the use of multi-parent advanced generation inter-cross (MAGIC) wheat populations, which allows fine mapping of resistance traits as a result of high level of genetic recombination(2). The aim of this study is to conduct accurate measurements of disease incidence and severity of STB using automated image analysis and visual assessment, on a UK MAGIC wheat population. A replicated field experiment using 300 wheat lines was carried out at the University of Reading Crops Research Unit, Sonning. The population was evaluated under natural STB infection at two time points (T1 and T2) separated by 56 days. Result showed that correlation between STB mean incidence at T1 and T2 was weak with rs = 0.25, p=6.1x10-6 while heritability values of 0.6866 (T1) and 0.4738 (T2) showed that STB resistance is largely heritable. STB severity measured as the percentage of leaf area covered by lesions ranged from 9.78% to 75.58%. This research will aid quantitative trait loci mapping in order to locate genetic markers correlating with STB resistance, to inform wheat breeding for sustainable STB control.
Triple-product asymmetry in the radiative two-pion tau decay
Creators: name: Chen, Cheng
name: Duan, Chun-Gui
name: Guo, Zhi-Hui
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this work, we perform a detailed study of the $τ^-\toπ^-π^0γν$ decay process within the resonance chiral theory. We pay special attention to the triple-product asymmetry in the $τ^-\toπ^-π^0γν$ process. The minimal resonance chiral Lagrangian and the odd-intrinsic parity resonance operators are simultaneously included to calculate the decay amplitudes. Various invariant-mass distributions in the $π^-π^0$, $π^-γ$ and $π^0γ$ systems are studied and they reveal different resonance dynamics. We further predict the intriguing nonzero triple-product asymmetry distributions, which may provide useful guidelines for future experimental measurements conducted at the Belle-II and super tau-charm facilities.
description: 32 pages, 9 figures. To match the published version
Bellavere's Scoring in chronic kidney disease: A Study Protocol
Creators: name: Saket Toshniwal
name: Kumar, Sunil
name: Sourya Acharya
Publisher: name: Zenodo
Year: 2023
Subjects: Cardiac autonomic neuropathy, chronic kidney disease, bellavere's score, heart rate variability, valsalva ratio, blood pressure, hemodialysis, end stage renal disease

description: Bellavere's Scoring in chronic kidney disease: A Study Protocol Abstract: Chronic kidney disease (CKD) refers to abnormalities in kidney structure and/or function for more than 3 months; Cardiac autonomic neuropathy (CAN) is an indicator of cardiovascular death due to various abnormalities such as cardiac arrhythmias. Heart rate variability (HRV) is an important component of CAN and has been shown to be related to CAN. This study aims to evaluate cardiac autonomic neuropathy at different stages of CKD with the Bellavere score and to correlate CAN with lipids, plasma, electrolytes and blood pressure in patients with CKD at different stages 95 consented patients who met the diagnosis of CKD according to MDRD criteria were included in the study. should be done. All subjects will have blood tests for lipids, anaemia, and electrolytes. All participants' blood pressure will be monitored. All subjects will also be scored based on the Bellevere scoring system, the Valsava ratio, and the 30:15 ratio. Data will be analyzed using SPSS version 21 and appropriate statistical tests will be used depending on the study objectives and the data collected. Based on the literature review and previous studies, the results of this study should demonstrate the relationship between CAN and CKD at this stage. The study was also expected to find higher Bellavere scores in patients with different stages of CKD.
Space-time adaptive ADER discontinuous Galerkin finite element schemes with a posteriori sub-cell finite volume limiting
Creators: name: Zanotti, Olindo
name: Fambri, Francesco
name: Dumbser, Michael
name: Hidalgo, Arturo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Numerical Analysis (math.NA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In this paper we present a novel arbitrary high order accurate discontinuous Galerkin (DG) finite element method on space-time adaptive Cartesian meshes (AMR) for hyperbolic conservation laws in multiple space dimensions, using a high order \aposteriori sub-cell ADER-WENO finite volume \emph{limiter}. Notoriously, the original DG method produces strong oscillations in the presence of discontinuous solutions and several types of limiters have been introduced over the years to cope with this problem. Following the innovative idea recently proposed in \cite{Dumbser2014}, the discrete solution within the troubled cells is \textit{recomputed} by scattering the DG polynomial at the previous time step onto a suitable number of sub-cells along each direction. Relying on the robustness of classical finite volume WENO schemes, the sub-cell averages are recomputed and then gathered back into the DG polynomials over the main grid. In this paper this approach is implemented for the first time within a space-time adaptive AMR framework in two and three space dimensions, after assuring the proper averaging and projection between sub-cells that belong to different levels of refinement. The combination of the sub-cell resolution with the advantages of AMR allows for an unprecedented ability in resolving even the finest details in the dynamics of the fluid. The spectacular resolution properties of the new scheme have been shown through a wide number of test cases performed in two and in three space dimensions, both for the Euler equations of compressible gas dynamics and for the magnetohydrodynamics (MHD) equations.
description: Computers and Fluids 118 (2015) 204-224
Multidrug-Resistant Gram-Negative Bacteria in Burn Patients
Creators: name: Chen L.
name: Bartelt L.
name: Kanumuambidi T.
name: Williams F.
name: Bonomo R.A.
name: Yen K.
name: Sozzi E.
name: Marshall S.H.
name: Brown D.
name: van Duin D.
name: Naziripour A.
name: Chu T.
name: Kreiswirth B.
name: Ruegsegger L.
name: Xiao J.
name: Rudin S.D.
Publisher: name: American Society for Microbiology
Year: 2022

description: Patients with burn injuries are at high risk for infectious complications, and infections are the most common cause of death after the first 72 h of hospitalization. Hospital-acquired infections caused by multidrug resistant (MDR) Gram-negative bacteria (GNB) in this population are concerning. Here, we evaluated carriage with MDR GNB in patients in a large tertiary-care burn intensive care unit. Twenty-nine patients in the burn unit were screened for intestinal carriage. Samples were cultured on selective media. Median time from admission to the burn unit to first sample collection was 9 days (IQR 5 – 17 days). In 21 (72%) patients, MDR GNB were recovered; the most common bacterial species isolated was Pseudomonas aeruginosa, which was found in 11/29 (38%) of patients. Two of these patients later developed bloodstream infections with P. aeruginosa. Transmission of KPC-31-producing ST22 Citrobacter freundii was detected. Samples from two patients grew genetically similar C. freundii isolates that were resistant to ceftazidime-avibactam. On analysis of whole-genome sequencing, blaKPC-31 was part of a Tn4401b transposon that was present on two different plasmids in each C. freundii isolate. Plasmid curing experiments showed that removal of both copies of blaKPC-31 was required to restore susceptibility to ceftazidime-avibactam. In summary, MDR GNB colonization is common in burn patients and patient-to-patient transmission of highly resistant GNB occurs. These results emphasize the ongoing need for infection prevention and antimicrobial stewardship efforts in this highly vulnerable population.
A Review on Deep-Learning Algorithms for Fetal Ultrasound-Image Analysis
Creators: name: Fiorentino, Maria Chiara
name: Villani, Francesca Pia
name: Di Cosmo, Mariachiara
name: Frontoni, Emanuele
name: Moccia, Sara
Publisher: name: arXiv
Year: 2022
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Deep-learning (DL) algorithms are becoming the standard for processing ultrasound (US) fetal images. Despite a large number of survey papers already present in this field, most of them are focusing on a broader area of medical-image analysis or not covering all fetal US DL applications. This paper surveys the most recent work in the field, with a total of 145 research papers published after 2017. Each paper is analyzed and commented on from both the methodology and application perspective. We categorized the papers in (i) fetal standard-plane detection, (ii) anatomical-structure analysis, and (iii) biometry parameter estimation. For each category, main limitations and open issues are presented. Summary tables are included to facilitate the comparison among the different approaches. Publicly-available datasets and performance metrics commonly used to assess algorithm performance are summarized, too. This paper ends with a critical summary of the current state of the art on DL algorithms for fetal US image analysis and a discussion on current challenges that have to be tackled by researchers working in the field to translate the research methodology into the actual clinical practice.
Additional file 1 of Retrospective analysis of a dedicated care pathway for nonalcoholic fatty liver disease in an integrated US healthcare system demonstrates support of weight management and improved ALT
Creators: name: Patton, Heather
name: Burchette, Raoul
name: Tovar, Stephanie
name: Pio, Jose
name: Jiaxiao Shi
name: Nyberg, Lisa M.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: Additional file 1. Comprehensive list of ICD9 and ICD 10 Codes used to identify atherosclerotic cardiovascular disease in study population as a comorbid health condition.
Considerations for the Use of Phage Therapy in Clinical Practice
Creators: name: Alexander J.
name: Van Duin D.
name: Chan B.K.
name: Rybak M.J.
name: Knisely J.M.
name: Hesse S.
name: Totten K.M.C.
name: Goodman K.E.
name: Patel R.
name: Campbell J.L.
name: Harris A.D.
name: Van Tyne D.
name: Lodise T.P.
name: Maresso A.
name: Suh G.A.
name: Pride D.
name: Aslam S.
name: Barton K.D.
name: Tamma P.D.
name: Bizzell E.
name: Cunningham S.A.
name: Greenwood-Quaintance K.E.
name: Nussenblatt V.
name: Sund Z.
Publisher: name: American Society for Microbiology
Year: 2022

description: Increasing antimicrobial resistance and medical device-related infections have led to a renewed interest in phage therapy as an alternative or adjunct to conventional antimicrobials. Expanded access and compassionate use cases have risen exponentially but have varied widely in approach, methodology, and clinical situations in which phage therapy might be considered. Large gaps in knowledge contribute to heterogeneity in approach and lack of consensus in many important clinical areas. The Antibacterial Resistance Leadership Group (ARLG) has convened a panel of experts in phage therapy, clinical microbiology, infectious diseases, and pharmacology, who worked with regulatory experts and a funding agency to identify questions based on a clinical framework and divided them into three themes: potential clinical situations in which phage therapy might be considered, laboratory testing, and pharmacokinetic considerations. Suggestions are provided as answers to a series of questions intended to inform clinicians considering experimental phage therapy for patients in their clinical practices.
Additional file 1: of Tau and atrophy: domain-specific relationships with cognition
Creators: name: Leonardino Digma
name: Madsen, John
name: Reas, Emilie
name: Dale, Anders
name: Brewer, James
name: Banks, Sarah
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Method S1. Assessing laterality of FTP-cognition and thickness-cognition associations. Method S2. Examining the affect of AÎ˛ on FTP-cognition and thickness cognition associations. Figure S1. Results from vertex-wise associations between FTP and cognitive scores, and between cortical thickness and cognitive scores. Figure S2. Results from Mengâ s test analyses on cortical thickness-cognition correlation maps. Figure S3. Distribution of Laterality Indices (LI) from each FTP-cognition and thickness-cognition vertex-wise analysis. Figure S4. Regional PVC-FTP and regional thickness are associated with cognition independent of AÎ˛ (DOCX 115582 kb)
Scintillation decay-time constants for alpha particles and electrons in liquid xenon
Creators: name: Cichon, Dominick
name: Eurin, Guillaume
name: Jörg, Florian
name: Undagoitia, Teresa Marrodán
name: Rupp, Natascha
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Understanding liquid xenon scintillation and ionization processes is of great interest to improve analysis methods in current and future detectors. In this paper, we investigate the dynamics of the scintillation process for excitation by $\mathcal{O}$(10 keV) electrons from a $^{83m}$Kr source and $\mathcal{O}$(6 MeV) $α$-particles from a $^{222}$Rn source, both mixed with the xenon target. The single photon sampling method is used to record photon arrival times in order to obtain the corresponding time distributions for different applied electric fields between about 0.8 V/cm to 1.2 kV/cm. Energy and field dependences of the signals which are observed in the results are discussed.
description: 11 pages, 9 figures; replaced with published manuscript version
Additional file 1 of Transdiagnostic treatment of emotional disorders for women with multiple sclerosis: a randomized controlled trial
Creators: name: Nazari, Nabi
name: Aligholipour, Akram
name: Sadeghi, Masoud
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Consort.
Characteristics of community-Acquired carbapenem-resistant Enterobacterales
Creators: name: Weston G.
name: Arias C.A.
name: Earley M.
name: Salata R.
name: Komarow L.
name: Anderson D.
name: Wong D.
name: Chen L.
name: Luterbach C.L.
name: Shrestha R.
name: Jacob J.T.
name: Dai W.
name: Rydell K.B.
name: Herc E.
name: Van Duin D.
Publisher: name: Oxford University Press
Year: 2022

description: Background: Community-Acquired carbapenem-resistant Enterobacterales (CA-CRE) are an important threat. Methods: In CRACKLE-2, we defined patients with CA-CRE as admitted from home, without pre-existing conditions, and a positive culture within 48 h of admission. Healthcare-Associated CRE (HA-CRE) were those with the lowest likelihood of community acquisition, not admitted from home and cultured >48 h after admission. Specific genetic markers in carbapenemase-producing Klebsiella pneumoniae were evaluated through random forest modelling. Results: CA-CRE and HA-CRE were detected in 83 (10%) and 208 (26%) of 807 patients. No significant differences were observed in bacterial species or strain type distribution. K. pneumoniae (204/291, 70%) was the most common CRE species, of these 184/204 (90%) were carbapenemase producers (CPKP). The top three genetic markers in random forest models were kpi_SA15, fimE, and kpfC. Of these, kpi_SA15 (which encodes a chaperone/usher system) was positively associated (OR 3.14, 95% CI 1.13-8.87, P = 0.026), and kpfC negatively associated (OR 0.21, 95% CI 0.05-0.72, P = 0.015) with CA-CPKP. Conclusions: Ten percent of CDC-defined CRE were CA. The true proportion of CA-CRE in hospitalized patients is likely lower as patients may have had unrecorded prior healthcare exposure. The kpi_SA15 operon was associated with the CA phenotype.
Clinical data from studies involving novel antibiotics to treat multidrug-resistant Gram-negative bacterial infections
Creators: name: Villegas M.V.
name: Van Duin D.
name: Kanj S.S.
name: Bassetti M.
name: Rodrigues C.
name: Kiratisin P.
name: Yu Y.
Publisher: name: Elsevier B.V.
Year: 2022

description: Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to global healthcare, worsening outcomes and increasing mortality among infected patients. Carbapenemase- and extended-spectrum β-lactamase-producing Enterobacterales, as well as carbapenemase-producing Pseudomonas and Acinetobacter spp., are common MDR pathogens. New antibiotics and combinations have been developed to address this threat. Clinical trial findings support several combinations, notably ceftazidime–avibactam (CZA, a cephalosporin-β-lactamase inhibitor combination), which is effective in treating complicated urinary tract infections (cUTI), complicated intra-abdominal infections and hospital-acquired and ventilator-associated pneumonia caused by GNBs. Other clinically effective combinations include meropenem–vaborbactam (MVB), ceftolozane–tazobactam (C/T) and imipenem–relebactam (I–R). Cefiderocol is a recent siderophore β-lactam antibiotic that is useful against cUTIs caused by carbapenem-resistant Enterobacterales (CRE) and is stable against many β-lactamases. Carbapenem-resistant Enterobacterales are a genetically heterogeneous group that vary in different world regions and are a substantial cause of infections, among which Klebsiella pneumoniae are the most common. Susceptible CRE infections can be treated with fluoroquinolones, aminoglycosides or fosfomycin, but alternatives include CZA, MVB, I–R, cefiderocol, tigecycline and eravacycline. Multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa are increasingly common pathogens producing a range of different carbapenemases, and infections are challenging to treat, often requiring novel antibiotics or combinations. Currently, no single agent can treat all MDR-GNB infections, but new β-lactam–β-lactamase inhibitor combinations are often effective for different infection sites and, when used appropriately, have the potential to improve outcomes. This article reviews clinical studies investigating novel β-lactam approaches for treatment of MDR-GNB infections.
Infectious Diseases Society of America 2022 Guidance on the Treatment of Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa)
Creators: name: Mathers A.J.
name: Aitken S.L.
name: Bonomo R.A.
name: van Duin D.
name: Clancy C.J.
name: Tamma P.D.
Publisher: name: Oxford University Press
Year: 2022

description: Background: The Infectious Diseases Society of America (IDSA) is committed to providing up-to-date guidance on the treatment of antimicrobial-resistant infections. The initial guidance document on infections caused by extended-spectrum β-lactamase producing Enterobacterales (ESBL-E), carbapenem-resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with difficult-to-treat resistance (DTR-P. aeruginosa) was published on 17 September 2020. Over the past year, there have been a number of important publications furthering our understanding of the management of ESBL-E, CRE, and DTR-P. aeruginosa infections, prompting a rereview of the literature and this updated guidance document. Methods: A panel of 6 infectious diseases specialists with expertise in managing antimicrobial-resistant infections reviewed, updated, and expanded previously developed questions and recommendations about the treatment of ESBL-E, CRE, and DTR-P. aeruginosa infections. Because of differences in the epidemiology of resistance and availability of specific anti-infectives internationally, this document focuses on the treatment of infections in the United States. Results: Preferred and alternative treatment recommendations are provided with accompanying rationales, assuming the causative organism has been identified and antibiotic susceptibility results are known. Approaches to empiric treatment, duration of therapy, and other management considerations are also discussed briefly. Recommendations apply for both adult and pediatric populations. Conclusions: The field of antimicrobial resistance is highly dynamic. Consultation with an infectious diseases specialist is recommended for the treatment of antimicrobial-resistant infections. This document is current as of 24 October 2021. The most current versions of IDSA documents, including dates of publication, are available at www.idsociety.org/practice-guideline/amr-guidance/.
Torrenticola (Torrenticola) mulherkarae Cook 1967
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Torrenticolidae
Torrenticola
Torrenticola mulherkarae

description: Torrenticola (Torrenticola) mulherkarae Cook, 1967
Records from the study area: Kerala—Cook (1967); Prasad (1974).
Habitat: Mountain streams.
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 16, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
Mechanical fluctuations suppress the threshold of soft-glassy solids : the secular drift scenario
Creators: name: Pons, Adeline
name: Amon, Axelle
name: Darnige, Thierry
name: Crassous, Jérôme
name: Clément, Eric
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We propose a dynamical mechanism leading to the fluidization of soft-glassy amorphous mate-rial driven below the yield-stress by external mechanical fluctuations. The model is based on the combination of memory effect and non-linearity, leading to an accumulation of tiny effects over a long-term. We test this scenario on a granular packing driven mechanically below the Coulomb threshold. We bring evidences for an effective viscous response directly related to small stress modulations in agreement with the theoretical prediction of a generic secular drift.
Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections
Creators: name: Aitken S.L.
name: Mathers A.J.
name: Bonomo R.A.
name: van Duin D.
name: Clancy C.J.
name: Tamma P.D.
Publisher: name: Oxford University Press
Year: 2022

description: The Infectious Diseases Society of America (IDSA) is committed to providing up-to-date guidance on the treatment of antimicrobial-resistant infections. A previous guidance document focused on infections caused by extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E), carbapenem-resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with difficult-to-treat resistance (DTR-P. aeruginosa). Here, guidance is provided for treating AmpC β-lactamase-producing Enterobacterales (AmpC-E), carbapenem-resistant Acinetobacter baumannii (CRAB), and Stenotrophomonas maltophilia infections. A panel of 6 infectious diseases specialists with expertise in managing antimicrobial-resistant infections formulated questions about the treatment of AmpC-E, CRAB, and S. maltophilia infections. Answers are presented as suggested approaches and corresponding rationales. In contrast to guidance in the previous document, published data on the optimal treatment of AmpC-E, CRAB, and S. maltophilia infections are limited. As such, guidance in this document is provided as "suggested approaches"based on clinical experience, expert opinion, and a review of the available literature. Because of differences in the epidemiology of resistance and availability of specific anti-infectives internationally, this document focuses on the treatment of infections in the United States. Preferred and alternative treatment suggestions are provided, assuming the causative organism has been identified and antibiotic susceptibility results are known. Approaches to empiric treatment, duration of therapy, and other management considerations are also discussed briefly. Suggestions apply for both adult and pediatric populations. The field of antimicrobial resistance is highly dynamic. Consultation with an infectious diseases specialist is recommended for the treatment of antimicrobial-resistant infections. This document is current as of 17 September 2021 and will be updated annually. The most current version of this document, including date of publication, is available at www.idsociety.org/practice-guideline/amr-guidance-2.0/.
NANOGrav Signal from the End of Inflation and the LIGO Mass and Heavier Primordial Black Holes
Creators: name: Ashoorioon, Amjad
name: Rezazadeh, Kazem
name: Rostami, Abasalt
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Releasing the 12.5-year pulsar timing array data, the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) has recently reported the evidence for a stochastic common-spectrum which would herald the detection of a stochastic gravitational wave background (SGWB) for the first time. We investigate if the signal could be generated from the end of a $\sim 10$ MeV but still phenomenologically viable double-field inflation when the field configuration settles to its true vacuum. During the double-field inflation at such scales, bubbles of true vacuum that can collapse to LIGO mass and heavier primordial black holes form. We show that only when this process happens with a first-order phase transition, the produced gravitational wave spectrum can match with the NANOGrav acclaimed SGWB signal. We show that the produced gravitational wave spectrum matches the NANOGrav SGWB signal only when this process happens through a first-order phase transition. Using LATTICEEASY, we also examine the previous observation in the literature that by lowering the scale of preheating, despite the shift of the peak frequency of the gravitational wave profile to smaller values, the amplitude of the SGWB could be kept almost constant. We notice that this observation breaks down at the preheating scale, $M\lesssim 10^{-14}~m_{{}_{\rm Pl}}$.
description: v3: matched the published version
Additional file 1 of The association between dietary insulin index and load with mental health
Creators: name: Darand, Mina
name: Amirinejad, Ali
name: Salehi-Abargouei, Amin
name: Davies, Ian G.
name: Mirzaei, Masoud
name: Mazidi, Mohsen
name: Khayyatzadeh, Sayyed Saeid
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Table S1. General characteristics of study participants [Mean ± SD or % (n) & OR (CI)] for presence of psychological disturbances.
Stark resonances in 2-dimensional curved quantum waveguides
Creators: name: Briet, Philippe
name: Gharsalli, Mounira
Publisher: name: arXiv
Year: 2015
Subjects: subject: Spectral Theory (math.SP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In this paper we study the influence of an electric field on a two dimen-sional waveguide. We show that bound states that occur under a geometrical deformation of the guide turn into resonances when we apply an electric field of small intensity having a nonzero component on the longitudinal direction of the system. MSC-2010 number: 35B34,35P25, 81Q10, 82D77.
Changing trends in mortality among solid organ transplant recipients hospitalized for COVID-19 during the course of the pandemic
Creators: name: Vianna R.
name: Hemmersbach-Miller M.
name: Diaz D.
name: Guitierrez J.
name: Diaz E.I.
name: Lease E.D.
name: UW COVID-19 Study Team
name: Munoz C.G.
name: Derenge A.C.
name: Tanna S.D.
name: Maximin A.
name: Velioglu A.
name: Malinis M.
name: Guerra G.
name: Multani A.
name: Haydel B.
name: Fisher C.E.
name: Azar M.M.
name: Goldman J.D.
name: Morillis J.A.
name: Rakita R.M.
name: Yabu J.M.
name: Hughes Kramer K.
name: van Duin D.
name: Alexander B.D.
name: Hemmige V.
name: Limaye A.P.
name: McCort M.E.
name: Chaudhry Z.S.
name: Mehta S.A.
name: Georgia S.J.
name: Heldman M.R.
name: Kates O.S.
name: La Hoz R.M.
name: Gilbert C.
name: Moni L.
name: Steinbrink J.M.
name: Singh P.P.
name: Loebe M.
name: Condor Y.
name: Ison M.
name: Flores S.
name: Safa K.
name: Kotton C.N.
Publisher: name: John Wiley and Sons Inc
Year: 2022

description: Mortality among patients hospitalized for COVID-19 has declined over the course of the pandemic. Mortality trends specifically in solid organ transplant recipients (SOTR) are unknown. Using data from a multicenter registry of SOTR hospitalized for COVID-19, we compared 28-day mortality between early 2020 (March 1, 2020–June 19, 2020) and late 2020 (June 20, 2020–December 31, 2020). Multivariable logistic regression was used to assess comorbidity-adjusted mortality. Time period of diagnosis was available for 1435/1616 (88.8%) SOTR and 971/1435 (67.7%) were hospitalized: 571/753 (75.8%) in early 2020 and 402/682 (58.9%) in late 2020 (p <.001). Crude 28-day mortality decreased between the early and late periods (112/571 [19.6%] vs. 55/402 [13.7%]) and remained lower in the late period even after adjusting for baseline comorbidities (aOR 0.67, 95% CI 0.46–0.98, p =.016). Between the early and late periods, the use of corticosteroids (≥6 mg dexamethasone/day) and remdesivir increased (62/571 [10.9%] vs. 243/402 [61.5%], p <.001 and 50/571 [8.8%] vs. 213/402 [52.2%], p <.001, respectively), and the use of hydroxychloroquine and IL-6/IL-6 receptor inhibitor decreased (329/571 [60.0%] vs. 4/492 [1.0%], p <.001 and 73/571 [12.8%] vs. 5/402 [1.2%], p <.001, respectively). Mortality among SOTR hospitalized for COVID-19 declined between early and late 2020, consistent with trends reported in the general population. The mechanism(s) underlying improved survival require further study.
Revisiting wind wave growth with fully-coupled direct numerical simulations
Creators: name: Wu, Jiarong
name: Popinet, Stéphane
name: Deike, Luc
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: We investigate wind wave growth by direct numerical simulations solving for the two phase Navier-Stokes equations. We consider ratio of the wave speed $c$ to wind friction velocity $u_*$ from $c/u_*=$ 2 to 8, i.e. in the slow to intermediate wave regime; and initial wave steepness $ak$ from 0.1 to 0.3; the two being varied independently. The turbulent wind and the travelling, nearly monochromatic waves are fully coupled without any subgrid scale models. The novel fully-coupled approach captures the simultaneous evolution of the wave amplitude and shape, together with the underwater boundary layer (drift current), up to wave breaking. The wave energy growth computed from the time-dependent rms surface elevation is in quantitative agreement with that computed from the extracted surface pressure distribution, which confirms the leading role of the pressure forcing for finite amplitude gravity waves. The phase shift and the amplitude of the principal mode of surface pressure distribution are systematically reported, to provide direct evidence for possible wind wave growth theories. For the momentum and energy fluxes, we find that the wave form drag force is not a strong function of wave age but closely related to wave steepness. The time evolution of the rms steepness and the wave form drag suggests that there is an effect of the history of wind wave coupling. The normalised wave growth rate we obtain agrees with previous experimental and numerical studies. We make an effort to clarify various commonly-adopted underlying assumptions, and to reconcile the scattering of the data between different previous theoretical, numerical, and experimental results, as we revisit this longstanding problem with new numerical evidence.
description: Published version: major revision to include discussion on steep waves and micro-breaking
Additional file 1: of Infant regulatory function acts as a protective factor for later traits of autism spectrum disorder and attention deficit/hyperactivity disorder but not callous unemotional traits
Creators: name: Bedford, Rachael
name: Gliga, Teodora
name: Hendry, Alexandra
name: Jones, Emily
name: Pasco, Greg
name: Charman, Tony
name: Johnson, Mark
name: Pickles, Andrew
Publisher: name: Figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Supplementary Materials. (DOCX 24 kb)
Situation and Professional Development Needs of Foreign Teachers in Thailand
Creators: name: Manita Srisitanont Luangkrajang
Publisher: name: Faculty of Liberal Arts, Prince of Songkla University
Year: 2023
Subjects: Foreign teachers
professional development needs
English language instruction

description: Journal of Liberal Arts, Prince of Songkla University, 15, 2, 269131, pp.1-18
Additional file 2 of The association between dietary insulin index and load with mental health
Creators: name: Darand, Mina
name: Amirinejad, Ali
name: Salehi-Abargouei, Amin
name: Davies, Ian G.
name: Mirzaei, Masoud
name: Mazidi, Mohsen
name: Khayyatzadeh, Sayyed Saeid
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. Table S2. Additional details about Dietary intakes of study participants across quartiles of dietary insulin index and load.
Additional file 1 of Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin
Creators: name: Quigley, Neil Gerard
name: Steiger, Katja
name: Richter, Frauke
name: Weichert, Wilko
name: Hoberück, Sebastian
name: Kotzerke, Jörg
name: Notni, Johannes
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Plant Biology

description: Additional file 1: Synthesis and analytical data for Triveoctin, radio-TLC for 68Ga-Triveoctin, and small-animal biodistribution data for 68Ga-Triveoctin in numerical form (table).
Development of Road Safety Discipline: Cultivation Strategies for Youth in School is Kamphaeng Phet Province
Creators: name: Jitti  Chommanarttikorn
Publisher: name: Pibulsongkram Rajabhat University
Year: 2023
Subjects: Strategy development of road safety disciplines
For youth
In schools
Kamphaeng phet province

description: Humanities and Social Sciences Journal of Pibulsongkram Rajabhat University, 17, 1, 292-307
D5.3 Methods for public engagement in European Food Safety System (FSS)
Creators: name: Scherbov, Maria
name: Sabini, Matteo
name: Hanne-Leena Alakomi
name: Cheren, Serena
name: Lattanzio, Veronica
name: Cito, Nunzia
name: Marschalek, Ilse
Publisher: name: Zenodo
Year: 2023

description: This deliverable presents a methodology for public engagement in the European Food Safety System (FSS) to address the lack of public awareness, limited engagement, and inadequate cross-sectoral cooperation, which pose significant risks to food safety in Europe.
 The methodology presented builds upon existing literature and public engagement approaches, offering insights into barriers hindering public engagement and potential solutions to overcome them. By incorporating these insights, individual food actors can enhance their strategies and contribute to a more reliable food safety system.
 The methodology developed in this document takes inspiration from the PE2020 project and incorporates three essential elements of public engagement: public communication, public consultation, and public deliberation. Two workshop formats, namely the public workshop format and the co-creation workshop format, are selected to implement this methodology.
 The co-creation workshop format promotes co-learning and co-deliberation among diverse stakeholders, facilitating the development of effective communication materials and strategies. It emphasizes diverse participation, idea generation, engaged participation, tangible outputs, collaboration, and consensus-building. The co-creation workshop format enables stakeholders to collaborate, exchange knowledge, and collectively develop communication materials, fostering an inclusive and dynamic environment.
 Meanwhile, the public event format serves as a tool to survey and understand societal concerns regarding food safety. It encourages inclusive participation, engagement of the public, a broad societal perspective, utilization of interactive tools, and informative and actionable outcomes. Public events provide an opportunity to capture comprehensive societal perspectives and inform recommendations and future research initiatives.
 The methodology also includes five additional public engagement tools developed by FoodSafety4EU, including a Communication Kit, TikTok videos, comics, educational materials, and the FSOLab Methodology Guidebook. These tools offer innovative ways to engage the public and can be easily adopted and reused in various contexts.
 Recommendations derived from the workshops emphasize:
 1. The need for innovative engagement methods to enhance food safety awareness, particularly in areas with limited literacy levels.
 2. The importance of fostering cross-collaboration during outbreaks to promote effective communication and coordination.
 Implementing this methodology and leveraging the recommended tools, may help food actors in the European Food Safety System to effectively enhance public engagement, build trust, for creating a more effective and reliable food safety system.
Additional file 2 of How and why do French medical students choose the specialty of infectious and tropical diseases? A national cross-sectional study
Creators: name: Peiffer-Smadja, Nathan
name: François-Daniel Ardellier
name: Thill, Pauline
name: Anne-Lise Beaumont
name: Gaud Catho
name: Osei, Lindsay
name: Dubée, Vincent
name: Bleibtreu, Alexandre
name: Lemaignen, Adrien
name: Thy, Michaël
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. Supplementary material: questionnaire.