cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Robotical Automation in CNC Machine Tools, A Review
Creators: name: Soori, Mohsen
name: Arezoo, Behrooz
name: Dastres, Roza
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 401406
subject: Machining
classificationCode: 401405
subject: Machine tools

description: Robotics and automation have significantly transformed CNC machining operations, enhancing productivity, precision, and efficiency. Robots are employed to load and unload raw materials, workpieces, and finished parts onto CNC machines. They can efficiently handle heavy and bulky components, reducing the demand of manual labor and minimizing the risk of injuries. Robots can also be used in CNC machine tools to perform tasks such as automatic tool changing system, part inspection, and workpiece positioning. Automation technologies, including in-line inspection systems and non-destructive testing methods, can be integrated into CNC machining cells to enhance accuracy and reduce scrap and rework in machining operations. These systems collect real-time data on process parameters and machine tool performance to predict maintenance, optimize machining parameters, and improve overall efficiency. In the study, applications of robotics and automation in modification of CNC machine tools are reviewed and discussed. Different applications of robotics and automations in CNC machine tools such as automated material handling, automatic tool changing, robotic work cells, adaptive machining, machine tending, quality inspection, data monitoring and analysis and production line integration are discussed. Thus, by analyzing recent achievements in published papers, new ideas and concepts of future research works are suggested. As a result, accuracy as well as productivity in process of part production can be enhanced by applying the robotics and automation in CNC machining operations.
Additional file 4 of Delineating family needs in the transition from hospital to home for children with medical complexity: part 1, a meta-aggregation of qualitative studies
Creators: name: van de Riet, L.
name: Alsem, M. W.
name: van der Leest, E. C.
name: van Etten-Jamaludin, F. S.
name: Maaskant, J. M.
name: van Woensel, J. B. M.
name: van Karnebeek, C. D.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4: Table S3. Synthesized findings represented throughout the included papers.
A Visual Odyssey To Improve Teaching Practice
Creators: name: Smith, Lesley
name: Casey, Autumn
name: Constantine, Lynne Scott
name: Ericson, Rebecca
name: Evmenova, Anya
name: Ewell, Mary
name: Hudson, Seth
name: Lee, Shawn
name: Lukes, Laura
name: Muir, Star
name: Nelson, Jill
name: Poms, Laura
name: Reid, Shelley
name: Samaras, Anastasia
Publisher: name: Mason Publishing Group, George Mason University Libraries
Year: 2015
Subjects: SOTL

description: Just as they ask their students to risk uncertainty, fifteen scholars at George Mason University stepped beyond their customary research paradigms to build fresh capacity via collaborative self-study of teaching and the medium of visually rich environments. Participants embarked on this visual odyssey as individuals, but they present as a collaborative (S3C). Drawing on data from individual projects, a concurrent meta-study, and the research of predecessor communities, they argue that self-study empowers scholars to excel outside their domains as interdisciplinary and transdisciplinary scholars, to "move out of their own way" in order to learn and to nurture the core authenticity of the teacher-scholar.

After a short introduction to the collaborative's work and research results, the audience will break out for a "gallery walk and talk" through the visual and textual work of S3C, with multiple opportunities for discussion. In the final 10-15 minutes, presenters and audience discuss how S3C research results might apply to participants' own teaching and learning.
description: Innovations in Teaching & Learning Conference Proceedings, Vol 7 (2015): The Science of Learning: Using Research to Improve Teaching
sj-docx-1-hol-10.1177_09596836221145362 – Supplemental material for Lake level evidence for a mid-Holocene East Asian summer monsoon maximum and the impact of an abrupt late-Holocene drought event on prehistoric cultures in north-central China
Creators: name: Zhang, Zhiping
name: Shen, Zhongwei
name: Zhang, Shanjia
name: Chen, Jie
name: Chen, Shengqian
name: Li, Dongxue
name: Zhang, Shuai
name: Liu, Xiangjun
name: Wu, Duo
name: Sheng, Yongwei
name: Tang, Qiuhong
name: Chen, Fahu
name: Liu, Jianbao
Publisher: name: SAGE Journals
Year: 2022
Subjects: Geography
History

description: Supplemental material, sj-docx-1-hol-10.1177_09596836221145362 for Lake level evidence for a mid-Holocene East Asian summer monsoon maximum and the impact of an abrupt late-Holocene drought event on prehistoric cultures in north-central China by Zhiping Zhang, Zhongwei Shen, Shanjia Zhang, Jie Chen, Shengqian Chen, Dongxue Li, Shuai Zhang, Xiangjun Liu, Duo Wu, Yongwei Sheng, Qiuhong Tang, Fahu Chen and Jianbao Liu in The Holocene
Development of an Interactive Human Body Digital Reusable Learning Object (RLO) to Provide Whole Body Systems-Based Learning in Vitamins and Minerals
Creators: name: Gallo, Sina
name: Good, Deborah J.
name: Akers, Jeremy
name: Walz, Anita
name: Baab, Lujean
Publisher: name: Mason Publishing Group, George Mason University Libraries
Year: 2015
Subjects: teaching online; technology-enriched; digital tools; learning strategies; Discipline-based education research (DBER)

description: University teaching and learning of vitamins and minerals has been limited to a nutrient by nutrient approach. However, most vitamins and minerals play extensive roles in and interact with multiple body systems. Researchers from Virginia Tech, James Madison, and George Mason Universities are developing a Reusable Learning Object (RLO) for the study of micronutrients needed by the skeletal system. The RLO will be a freely accessible platform and be designed as a layered human body to highlight different micronutrient actions in target systems. Links to scientific research articles, government Dietary Reference Intakes, and other web-based factual information will be provided. Undergraduate and graduate students enrolled in vitamins and minerals courses across the three institutions will serve as the control group (no exposure to RLO) in 2014 and treatment group (exposure to RLO) in 2015. This presentation will address the design of the RLO and provide results from year one regarding type of student learners as well as interest and perceived utility of digital objects. As the RLO can be applied to teach various concepts, this session will be of interest to faculty across the university, particularly science instructors and those who teach online courses.
description: Innovations in Teaching & Learning Conference Proceedings, Vol 7 (2015): The Science of Learning: Using Research to Improve Teaching
Using Omeka and Neatline to Facilitate Student Research in a Core Literature Class
Creators: name: Saunders, Catherine E.
Publisher: name: Mason Publishing Group, George Mason University Libraries
Year: 2015
Subjects: technology-enriched; digital tools; active learning; undergraduate research experiences; inquiry

description: This poster/demonstration session illustrates how the digital humanities publishing platform Omeka and its Neatline plugin can be used to guide students in a general education class through the process of conducting and reporting on a modest amount of original document-based research. The presentation centers around an Omeka/Neatline site created by students in an ENGH 202 (Texts and Contexts) section titled, "American Women's Bestsellers: Digital Humanities Perspectives." Students identified significant places in the novels they read, located primary sources that shed light on contemporary cultural associations with those places, created Omeka items based on the sources, and wrote item and exhibit text that explores the meaning of the place in the novel and in the culture from which the novel arose. The unfamiliar experience of using digital humanities tools encourages students to approach literary analysis from a fresh perspective, while Omeka's insistence on careful documentation of sources and Neatline's built-in geographic structure facilitate analysis that connects the course's twin themes: historical/cultural context and place. Participants will have the chance to interact with the Omeka site, which includes both student-created projects and instructor-created course materials.

Student projects are available online at http://202s15.cesaunders.net/ and the course materials (which may be reused/adapted/remixed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported license) are posted at http://202s15.cesaunders.net/cmtls.
description: Innovations in Teaching & Learning Conference Proceedings, Vol 7 (2015): The Science of Learning: Using Research to Improve Teaching
Associations between dyadic relationship quality and stepfamily functioning: A common fate modeling approach
Creators: name: Ganong, L.H.
name: Jensen, T.M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Clinical and empirical literatures have highlighted the value of attending to distinct dyads within stepfamilies to ensure the needs of various relationships are being met. From a family systems perspective, the growth and maintenance of positive dynamics within one dyadic relationship can yield gains in other relationships and shape the larger stepfamily environment. Research seeking to link information about dyads and larger stepfamily systems is often marked by single-informant data or measures that represent individual-level constructs. Methods intended to leverage multi-informant data as indicators of dyad- or family-level constructs (i.e., common fate modeling; CFM) offer valuable opportunities to expand our understanding of stepfamily experiences. Using a sample of 291 stepparent-parent dyads, our study uses multi-informant data and CFM to assess three dyad-level constructs (i.e., marital quality, marital confidence, and stepparent–child relationship quality) as correlates of three stepfamily-level constructs (i.e., cohesion, expressiveness, and harmony). Our findings illustrate meaningful linkages among dyadic relationships and broader stepfamily-level dynamics, specifically emphasizing the role of stepparent–child relationship quality and marital confidence in shaping stepfamily cohesion, expressiveness, and harmony. The results also signal the potential for substantive findings to vary with respect to the selected unit of analysis.
Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening
Creators: name: Muratov, Eugene N
name: Moraes, Carolina B
name: Andrade, Carolina Horta
name: Freitas-Junior, Lucio H
name: Braga, Rodolpho C
name: Franco, Caio Haddad
name: Melo-Filho, Cleber C
Publisher: name: Elsevier
Year: 2018

description: Chagas disease is a neglected tropical disease (NTD) caused by the protozoan parasite Trypanosoma cruzi and is primarily transmitted to humans by the feces of infected Triatominae insects during their blood meal. The disease affects 6-8 million people, mostly in Latin America countries, and kills more people in the region each year than any other parasite-born disease, including malaria. Moreover, patient numbers are currently increasing in non-endemic, developed countries, such as Australia, Japan, Canada, and the United States. The treatment is limited to one drug, benznidazole, which is only effective in the acute phase of the disease and is very toxic. Thus, there is an urgent need to develop new, safer, and effective drugs against the chronic phase of Chagas disease. Using a QSAR-based virtual screening followed by in vitro experimental evaluation, we report herein the identification of novel potent and selective hits against T. cruzi intracellular stage. We developed and validated binary QSAR models for prediction of anti-trypanosomal activity and cytotoxicity against mammalian cells using the best practices for QSAR modeling. These models were then used for virtual screening of a commercial database, leading to the identification of 39 virtual hits. Further in vitro assays showed that seven compounds were potent against intracellular T. cruzi at submicromolar concentrations (EC50 <-1μM) and were very selective (SI >30). Furthermore, other six compounds were also inside the hit criteria for Chagas disease, which presented activity at low micromolar concentrations (EC50 <10μM) against intracellular T. cruzi and were also selective (SI>15). Moreover, we performed a multi-parameter analysis for the comparison of tested compounds regarding their balance between potency, selectivity, and predicted ADMET properties. In the next studies, the most promising compounds will be submitted to additional in vitro and in vivo assays in acute model of Chagas disease, and can be further optimized for the development of new promising drug candidates against this important yet neglected disease.
sj-docx-1-pie-10.1177_09544089221145796 - Supplemental material for Dissolution and evolution effects on pressure fluctuations in a space micropump
Creators: name: Ren, Zhipeng
name: Hao, Honglei
name: Li, Deyou
name: Wang, Hongjie
name: Liu, Jintao
name: Li, Yong
Publisher: name: SAGE Journals
Year: 2022
Subjects: Engineering not elsewhere classified
Materials Engineering not elsewhere classified

description: Supplemental material, sj-docx-1-pie-10.1177_09544089221145796 for Dissolution and evolution effects on pressure fluctuations in a space micropump by Zhipeng Ren, Honglei Hao, Deyou Li, Hongjie Wang, Jintao Liu and Yong Li in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering
"Praxisnahes Datenmanagement: Erfolgreiche Projekte durch gute Planung": Konzeption einer Schulungsreihe zur Datenmanagementplanung für Forschende an zwei Hamburger Hochschulen
Creators: name: Lorenz, Marta
name: Schulze, Francesca
Publisher: name: Zenodo
Year: 2024
Subjects: FDM
Forschungsdatenmanagement
Schulung
Konzept

description: Im Rahmen der Projektarbeit für den Zertifikatskurs FDM 2023/2024 wurde ein modulares Schulungskonzept zur Datenmanagementplanung erstellt. Dieses Poster und das zugehörige Paper beschreiben kurz das Konzept und die ausgearbeiteten Module.
Distribution and relative predation risk of nekton reveal complex edge effects within temperate seagrass habitat
Creators: name: Geyer, Julie K.
name: Hovel, Kevin A.
name: Kenworthy, Matthew D.
name: Fodrie, F. Joel
name: Mahoney, Richard D.
Publisher: name: Elsevier
Year: 2018

description: Edge effects may be important drivers of community dynamics across marine habitat mosaics. Past research has consistently suggested that within temperate and sub-tropical seagrass habitats, organisms inhabiting meadow edges experience lower survivorship, presumably correlated with increased predation. However, these survivorship trends have not consistently translated to differences in faunal densities between edge and interior regions of seagrass meadows. We evaluated the evidence of edge effects on predation upon two dominant mesopredators within temperate eelgrass (Zostera marina) communities of the U.S. East Coast: blue crabs (Callinectes sapidus) and pinfish (Lagodon rhomboides). We considered three lines of data to arbitrate the null hypothesis that edge has no impact on distribution or predation on blue crabs or pinfish: (1) relative density as measured by catch-per-unit-effort (CPUE) of blue crabs and pinfish within edge (<1-m from unstructured sandflat boundaries) versus interior (>3-m from unstructured sandflat boundaries) regions of eelgrass meadows; (2) distribution of acoustically tagged red drum (Sciaenops ocellatus), a recognized predator of both blue crabs and pinfish, within eelgrass meadows (at 1-m bin resolution); and (3) relative mortality of tethered blue crabs and pinfish within edge versus interior regions of eelgrass meadows. Additionally, we manipulated seagrass shoot density to evaluate potential interactions between local habitat complexity and edge effects. We found no statistically detectable difference in catch rates of blue crabs or pinfish in edge versus interior habitats, and red drum detection frequencies were statistically indistinguishable moving from the seagrass-sandflat boundary toward the meadow interior. Despite these findings, we did record statistically and ecologically significant edge effects on predation rates of tethered blue crabs and pinfish. Counter to previous work, we found that blue crabs survived >2.5— longer, and pinfish survived >2— longer, along the meadow edge relative to interior. Furthermore, the strength of these predation-related edge effects was most notable for blue crabs within plots with higher shoot density, while the opposite pattern was true for pinfish. These findings are, in part, consistent with the dichotomy apparent in the seagrass literature with respect to edge effects on faunal density and survivorship. Additionally, our work provides new detail on how habitat edges may affect the population ecology of larger bodied, more mobile mesopredator species that have not received as much attention in previous studies (i.e., higher survivorship possible along edges).
Controlling release from 3D printed medical devices using CLIP and drug-loaded liquid resins
Creators: name: DeSimone, Joseph M.
name: Paradzinsky, Mark D.
name: Wang, Andrew Z.
name: Mecham, Michael B.
name: Carbon, Redwood City, CA 94063, USA
name: Luft, J. Christopher
name: Janusziewicz, Rima
name: Warner, Samuel B.
name: Mecham, Sue J.
name: Bloomquist, Cameron J.
Publisher: name: Elsevier
Year: 2018

description: Mass customization along with the ability to generate designs using medical imaging data makes 3D printing an attractive method for the fabrication of patient-tailored drug and medical devices. Herein we describe the application of Continuous Liquid Interface Production (CLIP) as a method to fabricate biocompatible and drug-loaded devices with controlled release properties, using liquid resins containing active pharmaceutical ingredients (API). In this work, we characterize how the release kinetics of a model small molecule, rhodamine B-base (RhB), are affected by device geometry, network crosslink density, and the polymer composition of polycaprolactone- and poly (ethylene glycol)-based networks. To demonstrate the applicability of using API-loaded liquid resins with CLIP, the UV stability was evaluated for a panel of clinically-relevant small molecule drugs. Finally, select formulations were tested for biocompatibility, degradation and encapsulation of docetaxel (DTXL) and dexamethasone-acetate (DexAc). Formulations were shown to be biocompatible over the course of 175-days of in vitro degradation and the clinically-relevant drugs could be encapsulated and released in a controlled fashion. This study reveals the potential of the CLIP manufacturing platform to serve as a method for the fabrication of patient-specific medical and drug-delivery devices for personalized medicine.
واقع تأثير السلوكيات الذاتية و الجماعية على طلب خدمات الهياكل الصحية القاعدية في الجزائر : دراسة حالة عيادات متعددة الخدمات في المنطقة الصحية الشرقية
Creators: name: عيساوي, نصر الدين
Publisher: name: Revue Economie, Gestion et Société
Year: 2017
Subjects: Social determinants of health, nearby community care, basic health care structures.

description: This paper is the first inventory of individual and collective behavioral influences on the demand for local care in Algeria. Long analyzed under the economic aspect, inequalities in health are today apprehended according to a multitude of sociological criteria, among them the individual and collective behaviors. Through this article, consideration is given to taking into account these determinants in their different aspects; an imperative priority of the public health promotion policy in Algeria.
description: Revue Economie, Gestion et Société, No 9 (2017)
Minority patient preferences, barriers, and facilitators for shared decision-making with health care providers in the USA: A systematic review
Creators: name: Thomas, Kathleen C
name: Richmond, Jennifer
name: Perez Jolles, Monica
Publisher: name: Elsevier
Year: 2019

description: OBJECTIVES: This systematic review of contemporary literature sought to better understand racial and ethnic minority patients' shared decision-making (SDM) preferences, challenges and facilitators. METHODS: Data sources were PubMed, CINAHL, Embase, Google Scholar, PsycINFO, Sociological Abstracts, and Web of Science databases for publications between 2011 and 2016. Publications were included if they studied SDM during the clinical encounter for minority adults in clinical care in the United States. We conducted a narrative, descriptive synthesis of each study. RESULTS: From over 5000 publications identified through the search strategy, 18 met eligibility criteria following an abstract and full text (n=685) review in Covidence. Studies focused on SDM in developing treatment plans (n=10), and were conducted in primary care (n=6) or hospital/health system settings (n=6). Patients' decision preferences ranged from physician-driven altogether or initially, to patient-driven style. A comprehensive list of SDM facilitators and barriers was developed. CONCLUSION: Despite strong policy and research SDM support to increase patient communication and a growing published literature, results suggest lack of representation of minority populations in contemporary literature. PRACTICE IMPLICATIONS: Provider training may be needed to facilitate patient-provider transition from a passive toward a more active SDM engagement over time while confidence, trust and rapport is established.
A semantic similarity based methodology for predicting protein-protein interactions: Evaluation with P53-interacting kinases
Creators: name: Tropsha, Alexander
name: Rai, Ruhi
name: Dong, Xialan
name: Zheng, Weifan
name: Cox, Steven
name: Christopherson, Laura
name: Schmitt, Charles
Publisher: name: Elsevier
Year: 2020

description: Biomedical literature contains unstructured, rich information regarding proteins, ligands, diseases as well as biological pathways in which they are involved. Systematically analyzing such textual corpus has the potential for biomedical discovery of new protein-protein interactions and hidden drug indications. For this purpose, we have investigated a methodology that is based on a well-established text mining tool, Word2Vec, for the analysis of PubMed full text articles to derive word embeddings, and the use of a simple semantic similarity comparison either by itself or in conjunction with k-Nearest Neighbor (kNN) technique for the prediction of new relationships. To test this methodology, three lines of retrospective analyses of a dataset with known P53-interacting proteins have been conducted. First, we demonstrated that Word2Vec semantic similarity can infer functional relatedness among all kinases known to interact with P53. Second, in a series of time-split experiments, we demonstrated that both a simple similarity comparison and kNN models built with papers published up to a certain year were able to discover P53 interactors described in later publications. Third, in a different scenario of time-split experiments, we examined the predictions of P53-interacting proteins based on the kNN models built on data prior to a certain split year for different time ranges past that year, and found that the cumulative number of correct predictions was indeed increasing with time. We conclude that text mining of research papers in the PubMed literature based on Word2Vec analysis followed by a simple similarity comparison or kNN modeling affords excellent predictions of protein-protein interactions between P53 and kinases, and should have wide applications in translational biomedical studies such as repurposing of existing drugs, drug-drug interaction, and elucidation of mechanisms of action for drugs.
sj-pdf-1-acr-10.1177_02841851221142226 - Supplemental material for Using structured templates or free text style in reporting CT staging on colon cancer: a national survey
Creators: name: Andersen, Rasmus Dam
name: Vils Pedersen, Malene Roland
name: Hesseldal, Laura
name: Rafaelsen, Søren Rafael
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110320 Radiology and Organ Imaging
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-acr-10.1177_02841851221142226 for Using structured templates or free text style in reporting CT staging on colon cancer: a national survey by Rasmus Dam Andersen, Malene Roland Vils Pedersen, Laura Hesselda and Søren Rafael Rafaelsen in Acta Radiologica
sj-docx-1-isp-10.1177_00207640221141589 – Supplemental material for Comparison of attitudes to media representation of mental illness between journalists and mental health professionals in Russia with German-speaking countries of Switzerland, Germany, and Austria
Creators: name: Eichenberg, Christiane
name: Strobl, Lilian
name: Jaeger, Tina
name: Kirsha, Alla
name: Laugharne, Richard
name: Shankar, Rohit
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-isp-10.1177_00207640221141589 for Comparison of attitudes to media representation of mental illness between journalists and mental health professionals in Russia with German-speaking countries of Switzerland, Germany, and Austria by Christiane Eichenberg, Lilian Strobl, Tina Jaeger, Alla Kirsha, Richard Laugharne and Rohit Shankar in International Journal of Social Psychiatry
High Deductible Health Plans and Use of Free Preventive Services Under the Affordable Care Act
Creators: name: Trogdon, Justin G.
name: Stearns, Sally C.
name: Shafer, Paul R.
name: Dusetzina, Stacie B.
name: Sabik, Lindsay M.
name: Platts-Mills, Timothy F.
Publisher: name: SAGE Publications
Year: 2023

description: The Affordable Care Act aimed to increase use of preventive services by eliminating cost-sharing to consumers. However, patients may be unaware of this benefit or they may not seek preventive services if they anticipate that the cost of potential diagnostic or treatment services will be too high, both more likely among those in high deductible health plans. We used nationally representative private health insurance claims (100% sample of IBM® MarketScan®) for the United States from 2006 to 2018, restricting the data to enrollment and claims for non-elderly adults who were enrolled for the full plan year. The cross-sectional sample (185 million person-years) is used to describe trends in preventive service use and costs from 2008 through 2016. The cohort sample (9 million people) focuses on the elimination of cost-sharing for certain high-value preventive services in late 2010, requiring continuous enrollment across 2010 and 2011. We examine whether HDHP enrollment is associated with use of eligible preventive services using semi-parametric difference-in-differences to account for endogenous plan selection. Our preferred model implies that HDHP enrollment was associated with a reduction of the post-ACA change in any use of eligible preventive services by 0.2 percentage points or 12.5%. Cancer screenings were unaffected but HDHP enrollment was associated with smaller increases in wellness visits, immunizations, and screening for chronic conditions and sexually transmitted infections. We also find that the policy was ineffective at reducing out-of-pocket costs for the eligible preventive services, likely due to implementation issues.
sj-docx-1-jte-10.1177_00224871221142845 – Supplemental material for The Development of Collaborative Advocacy: Dialogic Engagements Over Time and Texts
Creators: name: Michener, Catherine J.
name: Suh, Sora
Publisher: name: SAGE Journals
Year: 2022
Subjects: Education

description: Supplemental material, sj-docx-1-jte-10.1177_00224871221142845 for The Development of Collaborative Advocacy: Dialogic Engagements Over Time and Texts by Catherine J. Michener and Sora Suh in Journal of Teacher Education
Additional file 1 of SIMPD: an algorithm for generating simulated time splits for validating machine learning approaches
Creators: name: Landrum, Gregory A.
name: Beckers, Maximilian
name: Lanini, Jessica
name: Schneider, Nadine
name: Stiefl, Nikolaus
name: Riniker, Sereina
Publisher: name: figshare
Year: 2023
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1. Additional tables and figures.
Community Extraction in Multilayer Networks with Heterogeneous Community Structure.
Creators: name: Nobel, Andrew B
name: Bhamidi, Shankar
name: Palowitch, John
name: Wilson, James D
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Multilayer networks are a useful way to capture and model multiple, binary or weighted relationships among a fixed group of objects. While community detection has proven to be a useful exploratory technique for the analysis of single-layer networks, the development of community detection methods for multilayer networks is still in its infancy. We propose and investigate a procedure, called Multilayer Extraction, that identifies densely connected vertex-layer sets in multilayer networks. Multilayer Extraction makes use of a significance based score that quantifies the connectivity of an observed vertex-layer set through comparison with a fixed degree random graph model. Multilayer Extraction directly handles networks with heterogeneous layers where community structure may be different from layer to layer. The procedure can capture overlapping communities, as well as background vertex-layer pairs that do not belong to any community. We establish consistency of the vertex-layer set optimizer of our proposed multilayer score under the multilayer stochastic block model. We investigate the performance of Multilayer Extraction on three applications and a test bed of simulations. Our theoretical and numerical evaluations suggest that Multilayer Extraction is an effective exploratory tool for analyzing complex multilayer networks. Publicly available code is available at https://github.com/jdwilson4/MultilayerExtraction.
58749: Prisoner of War Letter
Creators: name: Project Team, Great War Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: This is the letter my grandmother received in 1914 from the German Army, I believe it portrays the element of moral decency of that period.
Walter Markham joined the 1st Batt. East Yorkshire Regiment in 1903 aged 16 years (he lied about his age). When the Great-War broke out his Battalion left for France on the 8th September 1914 and proceeded towards Aisne where they engaged the Germans in the 1st Battle of Aisne between Sep. 12th to 15th, theirs was the first East Yorkshire Battalion to see action in this war. The records show that the Germans used a high concentration of shrapnel bombs in this engagement and Walter received injuries from shrapnel and was subequently captured by the Germans and taken to 'Stead' POW camp and hospital where he was treated for his lifethreatening injuries. Whilst receiving treatment my grand-mother, who was unaware of his fate, received the letter from the prison camp. In 1915 he was amongst the first group of Excange Prisoners made between the Germans and Allies. He was discharged in 1916, after serving almost 13 years, as 'no longer physically fit for war service'. He was a lance-coporal, Regiment No. 7555.
sj-docx-1-cre-10.1177_02692155221149371 - Supplemental material for Preferences for cardiovascular and pulmonary rehabilitation care: A discrete choice experiment among patients in Lebanon
Creators: name: Farah, Rebecca
name: Groot, Wim
name: Pavlova, Milena
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-docx-1-cre-10.1177_02692155221149371 for Preferences for cardiovascular and pulmonary rehabilitation care: A discrete choice experiment among patients in Lebanon by Rebecca Farah, Wim Groot, and Milena Pavlova in Clinical Rehabilitation
Supplemental Material - Traumatized Sexuality: Understanding and Predicting Profiles of Sexual Behaviors Using Childhood Abuse and Trauma Measures
Creators: name: Gewirtz-Meydan, Ateret
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material for Traumatized Sexuality: Understanding and Predicting Profiles of Sexual Behaviors Using Childhood Abuse and Trauma Measures by Ateret Gewirtz-Meydan in Child Maltreatment
65995: Canadians
Creators: name: Project Team, First World War Poetry Digital Archive
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Typescript in red and black ink, with red ink punctuation corrections added 'conjecturally by M. M. S. (Marion Scott) as probably being what the poet intended.' Possibly amongst those poems submitted to and rejected by the firm Sidgwick and Jackson in 1922. Multiple versions of the poem survive. This version substitutes 'Jack London' for 'Quebec, Stewart White' in line 16, and is close to the draft included in P.J. Kavanagh's 'Ivor Gurney: Collected Poems' (2004).
PBRM1 Inactivation Promotes Upregulation of Human Endogenous Retroviruses in a HIF-Dependent Manner
Creators: name: Davis, Ian J.
name: Simon, Jeremy M.
name: Leung, Janet Y.
name: Kim, William Y.
name: Hepperla, Austin J.
name: Gessner, Kathryn H.
name: Zhou, Mi
Publisher: name: American Association for Cancer Research (AACR)
Year: 2022

description: Clear cell renal cell carcinoma (ccRCC) is considered an immunotherapy-responsive disease; however, the reasons for this remain unclear. Studies have variably implicated PBRM1 mutations as a predictive biomarker of immune checkpoint blockade (ICB) response, and separate studies demonstrate that expression of human endogenous retroviruses (hERV) might be an important class of tumor-associated antigens. We sought to understand whether specific mutations were associated with hERV expression. Two large, annotated genomic datasets, TCGA KIRC and IMmotion150, were used to correlate mutations and hERV expression. PBRM1 mutations were consistently associated with increased hERV expression in primary tumors. In vitro silencing of PBRM1, HIF1A, and HIF2A followed by RNA sequencing was performed in UMRC2 cells, confirming that PBRM1 regulates hERVs in a HIF1α- and HIF2α-dependent manner and that hERVs of the HERVERI superfamily are enriched in PBRM1-regulated hERVs. Our results uncover a role for PBRM1 in the negative regulation of hERVs in ccRCC. Moreover, the HIF-dependent nature of hERV expression explains the previously reported ccRCC-specific clinical associations of PBRM1-mutant ccRCC with both a good prognosis as well as improved clinical outcomes to ICB. See related Spotlight by Labaki et al., p. 274.
BOSHLANG'ICH SINF O'QUVCHILARINING KREATIVLIK QOBILIYATINI SHAKLLANTIRISH
Creators: name: Kulboyeva, Dilnoza
Publisher: name: Zenodo
Year: 2025

description: Ushbu  maqolada  boshlang‘ich sinf o‘quvchilarini  texnologiya  darslarida  turli materiallardan foydalanib, kreativligini shakllantirish haqida tavsiyalar, ma’lumotlar va tushunchalar berilgan.
Interactions between perceived stress and microbial-host immune components: two demographically and geographically distinct pregnancy cohorts
Creators: name: Meltzer-Brody, Samantha
name: Kimmel, Mary
name: Pe±alver Bernabe, Beatriz
name: Tussing-Humphreys, Lisa
name: Gilbert, Jack A.
name: Carroll, Ian M.
name: Cunningham, Janet L.
name: Maki, Pauline M.
name: Eisenlohr-Moul, Tory
Publisher: name: Springer Nature
Year: 2023

description: Higher stress during pregnancy associates with negative outcomes and elevated inflammation. The gut microbiota, reflecting environment and social interactions, alongside host immune responses have the potential to better understand perceived stress and identify when stress is excessive in pregnancy. Two U.S. cohorts of 84 pregnant individuals, composed of urban women of color and suburban white women, completed the Perceived Stress Scale-10 (PSS-10) and provided fecal and blood samples at two time points. Confirmatory Factor Analysis assessed the robustness of a two-factor PSS-10 model (Emotional Distress/ED and Self-Efficacy/SE). Gut microbiota composition was measured by 16S rRNA amplicon sequencing and the immune system activity was assessed with a panel of 21 T-cell related cytokines and chemokines. ED levels were higher in the suburban compared to the urban cohort, but levels of SE were similar. ED and SE levels were associated with distinct taxonomical signatures and the gut microbiota data improved the prediction of SE levels compared with models based on socio-demographic characteristics alone. Integration of self-reported symptoms, microbial and immune information revealed a possible mediation effect of Bacteroides uniformis between the immune system (through CXCL11) and SE. The study identified links between distinct taxonomical and immunological signatures with perceived stress. The data are congruent with a model where gut microbiome and immune factors, both impacting and reflecting factors such as close social relationships and dietary fiber, may modulate neural plasticity resulting in increased SE during pregnancy. The predictive value of these peripheral markers merit further study.
Supplemental Material - Effect of thermally induced microstructural changes on the mechanical properties and ballistic performance of poly (p-phenylene terephthalamide) fibers
Creators: name: Pramanick, Rinku
name: Verma, Sanjeev K
name: Kumari, Rajesh
name: De, Sirshendu
name: Neogi, Sudarsan
name: Neogi, Swati
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental Material for Effect of thermally induced microstructural changes on the mechanical properties and ballistic performance of poly (p-phenylene terephthalamide) fibers by Rinku Pramanick, Sanjeev K Verma, Rajesh Kumari, Sirshendu De, Sudarsan Neogi and Swati Neogi in High Performance Polymers
HPA axis response and psychosocial stress as interactive predictors of suicidal ideation and behavior in adolescent females: a multilevel diathesis-stress framework
Creators: name: Nock, Matthew K.
name: Rudolph, Karen D.
name: Giletta, Matteo
name: Prinstein, Mitchell J.
name: Hastings, Paul D.
name: Eisenlohr-Moul, Tory A.
name: Miller, Adam B.
Publisher: name: Springer Nature
Year: 2018

description: Prior studies suggest that hypothalamic-pituitary-adrenal (HPA) axis stress response is a relatively stable risk factor for suicidal behavior in adults, and also that fluctuations in developmentally salient social stress (i.e., peer stress) predict acute suicidal ideation and behavior in adolescent females. Here, we test the hypothesis that periods of high peer stress are prospectively associated with concurrent episodes of suicidal ideation and behavior, but that abnormal cortisol responses to stress at baseline act as a diathesis that strengthens this stressor-suicidality link, using a longitudinal, multi-wave study design. We measured cortisol responses to an adolescent modification of the Trier Social Stress Test in 220 adolescent females recruited for mental health concerns, and measured stress (peer, academic, and mother-child) and suicidal ideation and behaviors repeatedly across 18 months. Logistic multilevel models revealed the predicted interaction between altered cortisol response and elevated periods of peer stress in predicting suicidal behavior, but not ideation. Higher-than-usual peer stress predicted suicidal ideation regardless of HPA function, but predicted suicide attempt only among those with blunted cortisol responses. Results suggest that peer stress serves to trigger suicidal ideation among female youth, but only triggers suicidal behavior among those with blunted cortisol reactivity.
Appendix I from Apparent differential phenotypic responses by kelp forest grazers to disease-driven removal of sea star predators
Creators: name: Wetmore, Lynne Saradpon
name: Anderson, Todd
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Physical/oceanographic, environmental, and habitat characteristics of paired SS+/SS- sites in each region.
Additional file 1 of The association of conspiracy beliefs and the uptake of COVID-19 vaccination: a cross-sectional study
Creators: name: Kowalska-Duplaga, Kinga
name: Duplaga, Mariusz
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Supplemental Material - A Model for Inhomogeneously Broadened Raman Bands
Creators: name: Jakubek, Ryan S.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental Material for A Model for Inhomogeneously Broadened Raman Bands by Ryan S. Jakubek in Applied Spectroscopy
Appendix III from Apparent differential phenotypic responses by kelp forest grazers to disease-driven removal of sea star predators
Creators: name: Wetmore, Lynne Saradpon
name: Anderson, Todd
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Variability, range, and % mean difference between paired SS+/SS- sites for shell shape (SH:SW; representing growth over the total lifespan of the snail) vs. aperture shape (AH:AW; representing the region of most recent shell growth).
A simultaneous [11C]raclopride positron emission tomography and functional magnetic resonance imaging investigation of striatal dopamine binding in autism
Creators: name: Truong, Kinh
name: Pizzagalli, Diego A.
name: Tseng, Chieh-En J.
name: Phillips, Rachel D.
name: Izquierdo-Garcia, David
name: Zuercher, Nicole R.
name: Dharanikota, Ayarah
name: Walsh, Erin C.
name: Lalush, David
name: Dichter, Gabriel S.
name: Hooker, Jacob M.
name: Kinard, Jessica L.
name: Smith, Eric
name: Dillon, Daniel
name: Bizzell, Joshua C.
name: Li, Zibo
name: Cernasov, Paul M.
name: Greene, Rachel K.
Publisher: name: Springer Nature
Year: 2021

description: The social motivation hypothesis of autism posits that autism spectrum disorder (ASD) is characterized by impaired motivation to seek out social experience early in life that interferes with the development of social functioning. This framework suggests that impaired mesolimbic dopamine function underlies compromised responses to social rewards in ASD. Although this hypothesis is supported by functional magnetic resonance imaging (fMRI) studies, no molecular imaging study has evaluated striatal dopamine functioning in response to rewards in ASD. Here, we examined striatal functioning during monetary incentive processing in ASD and controls using simultaneous positron emission tomography (PET) and fMRI. Using a bolus+infusion protocol with the D2/D3 dopamine receptor antagonist [11C]raclopride, voxel-wise binding potential (BPND) was compared between groups (controls=12, ASD=10) in the striatum. Striatal clusters showing significant between-group BPND differences were used as seeds in whole-brain fMRI general functional connectivity analyses. Relative to controls, the ASD group demonstrated decreased phasic dopamine release to incentives in the bilateral putamen and left caudate, as well as increased functional connectivity between a PET-derived right putamen seed and the precuneus and insula. Within the ASD group, decreased phasic dopamine release in the putamen was related to poorer theory-of-mind skills. Our findings that ASD is characterized by impaired striatal phasic dopamine release to incentives provide support for the social motivation hypothesis of autism. PET-fMRI may be a suitable tool to evaluate novel ASD therapeutics targeting the striatal dopamine system.
The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells
Creators: name: Kardos, Jordan
name: Weissman, Bernard
name: Major, Michael B.
name: Mutter-Rottmayer, Elizabeth
name: Kim, William Y.
name: Gao, Yanzhe
name: Vaziri, Cyrus
name: Yang, Yang
name: Tamir, Tigist Y.
Publisher: name: Springer Nature
Year: 2018

description: The Cancer/Testes (CT) Antigen HORMAD1 is germ cell-restricted and plays developmental roles in generation and processing of meiotic DNA Double Strand Breaks (DSB). Many tumors aberrantly overexpress HORMAD1 yet the potential impact of this CT antigen on cancer biology is unclear. We tested a potential role of HORMAD1 in genome maintenance in lung adenocarcinoma cells. We show that HORMAD1 re-distributes to nuclear foci and co-localizes with the DSB marker γH2AX in response to ionizing radiation (IR) and chemotherapeutic agents. The HORMA domain and C-term disordered oligomerization motif are necessary for localization of HORMAD1 to IR-induced foci (IRIF). HORMAD1-depleted cells are sensitive to IR and camptothecin. In reporter assays, Homologous Recombination (HR)-mediated repair of targeted ISce1-induced DSBs is attenuated in HORMAD1-depleted cells. In Non-Homologous End Joining (NHEJ) reporter assays, HORMAD1-depletion does not affect repair of ISce1-induced DSB. Early DSB signaling events (including ATM phosphorylation and formation of γH2AX, 53BP1 and NBS1 foci) are intact in HORMAD1-depleted cells. However, generation of RPA-ssDNA foci and redistribution of RAD51 to DSB are compromised in HORMAD1-depleted cells, suggesting that HORMAD1 promotes DSB resection. HORMAD1-mediated HR is a neomorphic activity that is independent of its meiotic partners (including HORMAD2 and CCDC36. Bioinformatic analysis of TCGA data show that similar to known HR pathway genes HORMAD1 is overexpressed in lung adenocarcinomas. Overexpression of HR genes is associated with specific mutational profiles (including copy number variation). Taken together, we identify HORMAD1-dependent DSB repair as a new mechanism of radioresistance and a probable determinant of mutability in lung adenocarcinoma.
sj-pdf-1-ejt-10.1177_13540661221143214 – Supplemental material for Does Russian election interference damage support for US alliances? The case of Japan
Creators: name: Goldsmith, Benjamin E.
name: Horiuchi, Yusaku
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-1-ejt-10.1177_13540661221143214 for Does Russian election interference damage support for US alliances? The case of Japan by Benjamin E. Goldsmith and Yusaku Horiuchi in European Journal of International Relations