cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Subtle changes in plant diversity in the Bavarian Alps over the past eight decades
Creators: name: Zettlemoyer, Meredith A.
name: Munck, Svenja
name: Poschlod, Peter
name: Rosbakh, Sergey
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: (sub)alpine vegetation, Alps, community composition, functional diversity, global change, grassland, historical record, re-survey, richness, stability
subject: 570 Biowissenschaften, Biologie
subject: 580 Pflanzen (Botanik)

description: Historical resurveys represent a unique opportunity to analyze vegetation dynamics over longer timescales than is typically achievable. Leveraging the oldest historical dataset of vegetation change in the Bavarian Alps, Germany, we address how environmental conditions, vegetation composition, and functional diversity in the calcareous grasslands of the Schachen region have changed across different elevational ranges over an 83-year timeframe. We document changes in regional average temperature and precipitation. We use indicator values (IV) for species' ecological preferences and their palatability to grazers to infer local conditions (temperature, soil moisture/fertility, and grazing regime). We further estimate changes in temporal beta-diversity and functional trait community composition between historical (1936) and contemporary (2019) surveys in two elevational (subalpine and alpine) belts. Both subalpine and alpine sites became drier; subalpine sites also became warmer with more palatable plants. Species occurrence and abundance in the Schachen region has not changed substantially over time despite changing macroclimate and local environmental conditions under anthropogenic change. Yet these grasslands have experienced several “invisible” changes in functional composition over the past 80 years. As the Schachen has become drier, species with traits related to drought tolerance and animal-based dispersal have increased in dominance. Specifically, in alpine sites, community-weighted means revealed that with low fecundity, higher potential for endo- and epizoochory (seed dispersal via animal gut and fur, respectively), higher foliar frost tolerance, and deeper dormancy increased in dominance. Similar trends were found for increasing dominance of low fecundity, epizoochorous species in subalpine sites. Vegetation data from resurveying historical plots in combination with changes in local conditions, classic biodiversity indices, and functional trait indices can provide more holistic insights into changes in the environment and potential impacts of those environmental changes on long-term plant community and functional diversity.
“Update prognostic potency of surfactant protein D (SP-D) in the COVID-19 landscape: an In-depth meta-analytical exploration”
Creators: name: Bastani, Mohammad-Navid
name: Jalilian, Shahram
name: Bahreiny, Seyed Sobhan
name: Makvandi, Manoochehr
name: Aghaei, Mojtaba
name: Mansouri, Zahra
name: Karamali, Negin
name: Sakhavarz, Tannaz
name: Amraei, Mahdi
name: Harooni, Elnaz
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Surfactant Protein D (SP-D), a key component of the innate immune system, has attracted significant interest for its potential role in the pathophysiology and prognosis of COVID-19. This systematic review and meta-analysis aim to clarify the prognostic importance of SP-D levels in COVID-19 patients. A comprehensive literature search was conducted using PubMed, Web of Science, Cochrane Library, Scopus, EMBASE, and Google Scholar, covering studies published from January 2000 to January 2024. The inclusion criteria focused on studies measuring SP-D levels in the serum or plasma of COVID-19 patients, comparing severe and non-severe cases. Standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated using a random-effects model to assess overall effect sizes. Meta-regressions and subgroup analyses were performed to identify potential sources of heterogeneity, including patient age, assay techniques, and gender ratio. The meta-analysis incorporated data from nine studies involving 5,410 COVID-19 patients. Elevated SP-D levels were significantly correlated with increased disease severity, yielding an SMD of 0.642 (95% CI: 0.314 to 0.870; p = 0.012). This meta-analysis confirms the prognostic significance of SP-D in the context of COVID-19. Elevated SP-D levels are associated with severe disease outcomes, highlighting its potential as a prognostic biomarker.
Neoribates (Neoribates) Berlese 1914
Creators: name: Yu, Bixiao
name: Pan, Xue
name: Liu, Dong
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Parakalummidae
Neoribates

description: Subgenus Neoribates (Neoribates) Berlese, 1914
Type species: Oribata roubali Berlese, 1910
description: Published as part of Yu, Bixiao, Pan, Xue & Liu, Dong, 2024, Neoribates (Neoribates) subiasi sp. nov. (Acari, Oribatida, Parakalummidae) from Changbai Mountain, China, pp. 122-131 in Zootaxa 5556 (1) on page 123, DOI: 10.11646/zootaxa.5556.1.11, http://zenodo.org/record/14595036
Additional file 1: Table S1. of Correlates of meeting the combined and independent aerobic and strength exercise guidelines in hematologic cancer survivors
Creators: name: Vallerand, James
name: Rhodes, Ryan
name: Walker, Gordon
name: Courneya, Kerry
Publisher: name: Figshare
Year: 2017
Subjects: Space Science
Medicine
Cell Biology
Marine Biology
Cancer
Computational Biology

description: Multinomial regression of demographic and cancer-specific correlates comparing combined, aerobic-only, and strength-only guidelines versus neither. Table S2. Pairwise comparisons of exercise-specific motivations, regulations, and reflective processes versus neither guideline. (DOCX 22 kb)
Additional file 2: Table S1. of A process evaluation plan for assessing a complex community-based maternal health intervention in Ogun State, Nigeria
Creators: name: Sumedha Sharma
name: Olalekan Adetoro
name: Vidler, Marianne
name: Drebit, Sharla
name: Payne, Beth
name: Akeju, David
name: Akinmade Adepoju
name: Ebunoluwa Jaiyesimi
name: Sotunsa, John
name: Bhutta, Zulfiqar
name: Magee, Laura
name: Dadelszen, Peter Von
name: Olukayode Dada
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Final plan to measure the construct of implementation. (DOCX 17 kb)
MOESM3 of
                     Citrobacter amalonaticus Y19 for constitutive expression of carbon monoxide-dependent hydrogen-production machinery
Creators: name: Ainala, Satish
name: Eunhee Seol
name: Kim, Jung
name: Sunghoon Park
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Computational Biology

description: Additional file 3: Table S2. The gentype of the promoter replaced Y19-PR1 strain.
Central immunological position of the human blood group O in light of the Duffy groups.
Creators: name: Arend, Peter
Publisher: name: Figshare
Year: 2017
Subjects: Cancer

description: Blood
group A phenotype development is associated with the impaired formation of
adaptive and innate immunoglobulins due to clonal selection and phenotypic,
glycosidic accommodation of the plasma proteins. This group is significantly
burdened with an increased risk of developing distinct types of cancer when
compared with the blood group O and is exerting strong susceptibility to Malaria
tropica or infection by Plasmodium
falciparum. While Malaria tertiana, caused by Plasmodium vivax, ovale and
knowlesi, is the best documented type of malaria, P. falciparum causes the most severe disease. In both malaria
types, the risk of developing the disease is molecularly
strongly related to blood group phenotype formation, although with reverse outcomes; while the Duffy positive (Fya)
individuals are most susceptible to P. vivax infections, but the Duffy antigen receptor for chemokines (DARC) protein
exerts cancer regulation, the human blood group A shows significant susceptibility
to both life-threatening infection by P.
falciparum and distinct types of cancer. Aside from the molecular features
of the DARC protein, the phenotype-determining glycotransferase(s) from blood
group A, affecting the levels of anti-A/Tn cross-reactive immuno-globulins, may also
initiate the entry of Plasmodium merozoites
into the host's red blood cells (RBCs) via the parasite's serine repeat antigen
(SERA), which when exposed to cancerous GalNAcα1-O-Ser/Thr-R, "A-like" (Tn) glycosylation, may provide the invasion of the parasite
into a cancer cell as well. In contrast, the human blood group O is currently
discussed to have a survival advantage of the overall risk of developing cancer;
moreover, it rarely develops life-threatening malaria disease and offers the
widest functional flexibility in adaptive and germline-encoded innate immunity.
Additional file 2: of Dimensions of sustainability for a health communication intervention in African American churches: a multi-methods study
Creators: name: Scheirer, Mary
name: Santos, Sherie
name: Tagai, Erin
name: Bowie, Janice
name: Slade, Jimmie
name: Carter, Roxanne
name: Holt, Cheryl
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: 12-month Womenâ  s Participant Survey. This survey was completed by female Project HEAL participants at the 12-month workshop. (PDF 2806 kb)
Additional file 5: of Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Creators: name: Cole, John
name: Robertson, Neil
name: Rather, Mohammed
name: Thomson, John
name: McBryan, Tony
name: Sproul, Duncan
name: Wang, Tina
name: Brock, Claire
name: Clark, William
name: Ideker, Trey
name: Meehan, Richard
name: Miller, Richard
name: Brown-Borg, Holly
name: Adams, Peter
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary figures. Supplementary figures for this manuscript. (PDF 2707 kb)
Additional file 3: Table S2. of A process evaluation plan for assessing a complex community-based maternal health intervention in Ogun State, Nigeria
Creators: name: Sumedha Sharma
name: Olalekan Adetoro
name: Vidler, Marianne
name: Drebit, Sharla
name: Payne, Beth
name: Akeju, David
name: Akinmade Adepoju
name: Ebunoluwa Jaiyesimi
name: Sotunsa, John
name: Bhutta, Zulfiqar
name: Magee, Laura
name: Dadelszen, Peter Von
name: Olukayode Dada
Publisher: name: Figshare
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy

description: Final plan to assess the mechanisms of impact of CLIP intervention. (DOCX 15 kb)
Flipped $SU(5)$ GUT with conformal gravity from a single supermultiplet
Creators: name: Chester, David
name: Marrani, Alessio
name: Rios, Michael
name: Irwin, Klee
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The Grassmann envelope is used to find the $\mathcal{N}=1$ `superquasiconformal' algebra in $D=10+1$. The adjoint representation of this algebra is found to contain $\mathfrak{su}_{2,2}\oplus \mathfrak{u}_{1}\oplus \mathfrak{su}_{5}$ as a submaximal subalgebra, giving a spectrum of conformal gravity with flipped $SU_{5}\times U_{1}$ GUT. Combining Yang-Mills theory with MacDowell-Mansouri gravity over the conformal group is found to recover the Einstein-Hilbert action with a cosmological constant. An action for the theory is presented, which contains the gauge bosons of gravity and GUT, three generations of fermions in an efficient manner, and a new Higgs sector. By using the superalgebra for the entire multiplet, the theory gauges a non-supersymmetric subalgebra without introducing superpartners.
description: 9 pages. Contribution to the Proceedings of the 28th International Conference on Integrable Systems and Quantum Symmetries (ISQS-28), Prague, Czechia, July 1-5, 2024
Additional file 5: of Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Creators: name: Cole, John
name: Robertson, Neil
name: Rather, Mohammed
name: Thomson, John
name: McBryan, Tony
name: Sproul, Duncan
name: Wang, Tina
name: Brock, Claire
name: Clark, William
name: Ideker, Trey
name: Meehan, Richard
name: Miller, Richard
name: Brown-Borg, Holly
name: Adams, Peter
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary figures. Supplementary figures for this manuscript. (PDF 2707 kb)
title: Adaptive Hashing
title: Faster Hash Functions with Fewer Collisions
titleType: Subtitle
Creators: name: Melis, Gábor
Publisher: name: Zenodo
Year: 2024

description: Hash tables are ubiquitous, and the choice of hash function, which maps a key to a bucket, is key for their performance. We argue that the predominant approach of fixing the hash function for the lifetime of the hash table is suboptimal and propose adapting it to the current set of keys. In the prevailing view, good hash functions spread the keys "randomly'' and are fast to evaluate. General-purpose ones (e.g. Murmur) are designed to do both while remaining agnostic to the distribution of the keys, which limits their bucketing ability and wastes computation. When these shortcomings are recognised, the user of the hash table may specify a hash function more tailored to the expected key distribution, but doing so almost always introduces an unbounded risk in case their assumptions do not bear out in practice. At the other, fully key-aware end of the spectrum, Perfect Hashing algorithms can discover hash functions to bucket a given set of keys optimally, but they are costly to run and require the keys to be known and fixed ahead of time. Our main conceptual contribution is that adapting the hash table's hash function to the keys online is necessary for the best performance as adaptivity allows for better bucketing of keys and faster hash functions. We instantiate the idea of online adaptation with minimal overhead and no change to the hash table API. The experiments show that the adaptive approach marries the common-case performance of weak hash functions with the robustness of general-purpose ones.
Additional file 1: of New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali
Creators: name: Dara, Antoine
name: DrĂĄbek, Elliott
name: Travassos, Mark
name: Moser, Kara
name: Delcher, Arthur
name: Su, Qi
name: Hostelley, Timothy
name: Drissa Coulibaly
name: Modibo Daou
name: Ahmadou Dembele
name: Diarra, Issa
name: Abdoulaye Kone
name: Bourema Kouriba
name: Laurens, Matthew
name: Amadou Niangaly
name: Traore, Karim
name: Tolo, Youssouf
name: Fraser, Claire
name: Mahamadou Thera
name: Abdoulaye Djimde
name: Ogobara Doumbo
name: Plowe, Christopher
name: Silva, Joana
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: A file containing Supplementary Tables S1â  S7. Table S1: Samples and respective metadata. Table S2: Genomic DNA: Illumina and PacBio Sequencing Statistics. Table S3: Assembly characteristics for 12 Malian samples generated by Sprai and Celera assemblers. Table S4: Exon 1 var sequences recovered with ETHA compared to raw var-like sequences extracted directly from assemblies. Table S5: Percent of extracted sequence absent from the ETHA output. Table S6: Comparison of PfEMP1 constitutive domains reconstructed from 12 samples to the reference 3D7. Table S7: Average percent (%) amino acid identity within PfEMP1 constitutive domains. (DOCX 64 kb)
The concurrent game semantics of Probabilistic PCF
Creators: name: Castellan, S
name: Clairambault, P
name: Paquet, H
name: Winskel, G
Publisher: name: Association for Computing Machinery
Year: 2018
Subjects: 46 Information and Computing Sciences
4904 Pure Mathematics
49 Mathematical Sciences
50 Philosophy and Religious Studies
5003 Philosophy

description: We define a new games model of Probabilistic PCF (PPCF) by enriching thin concurrent games with symmetry, recently introduced by Castellan et al, with probability. This model supports two interpretations of PPCF, one sequential and one parallel. We make the case for this model by exploiting the causal structure of probabilistic concurrent strategies. First, we show that the strategies obtained from PPCF programs have a deadlock-free interaction, and therefore deduce that there is an interpretation-preserving functor from our games to the probabilistic relational model recently proved fully abstract by Ehrhard et al. It follows that our model is intensionally fully abstract. Finally, we propose a definition of probabilistic innocence and prove a finite definability result, leading to a second (independent) proof of full abstraction.
Eryngiopus Summers 1964
Creators: name: Khanjani, M.
name: Hajizadeh, J.
name: Ueckermann, E. A.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Prostigmata
Stigmaeidae
Eryngiopus

description: Genus Eryngiopus Summers1964.
Type species: Eryngiopus gracilis Summers 1964, by original designation.
Diagnosis — female (based on Fan and Zhang, 2005): Chelicerae hinged at base. Palp tibial claw almost as long as palp tarsus; accessory claw slender, seta-like or spine-like; terminal eupathidia on palp tarsus mostly fused and split into 2-3 vestigial prongs; counts of setae and solenidia, from palp trochanter to palp tarsus: 0, 3, 1, 2+1 claw+1 accessory claw, 4+1ω+1 sub terminal spine-like eupathidium+3 eupathidia (mostly fused). Subcapitulum with two pairs of subcapitular long to short setae, m posterolaterad of pharynx, n posteromediad of m. Prodorsum reticulate to striate, eyes present. Dorsal hysterosomal area C-F mainly striated, setae d 1 and d 2 situated on tiny platelets; humeral shields minute or vestigial, dorsolateral, with setae c 2; intercalary shields (F) divided along midline, each side with one seta (f 1). Suranal shield (H) divided or entire, with 2 pairs of setae (h 1 and h 2), h 3 absent. Venter with 3 pairs of intercoaxal setae 1a, 3a, 4a and 2-3 pairs of aggenital setae (ag1-3 or ag1-2); genitoanal valves with 1 pair of genital setae (g1), and 3 pairs of pseudanal setae. Leg tarsal claws robust; empodial shafts branching into tenent hairs before extending beyond tips of claws, with 3 pairs of tenent hairs.
description: Published as part of Khanjani, M., Hajizadeh, J. & Ueckermann, E. A., 2014, Eryngiopus Langroudiensis N. Sp. (Acari: Stigmaeidae) From Guilan, Iran, pp. 171-176 in Acarologia 54 (2) on page 172, DOI: 10.1051/acarologia/20142124, http://zenodo.org/record/4667270
Additional file 1: of New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali
Creators: name: Dara, Antoine
name: DrĂĄbek, Elliott
name: Travassos, Mark
name: Moser, Kara
name: Delcher, Arthur
name: Su, Qi
name: Hostelley, Timothy
name: Drissa Coulibaly
name: Modibo Daou
name: Ahmadou Dembele
name: Diarra, Issa
name: Abdoulaye Kone
name: Bourema Kouriba
name: Laurens, Matthew
name: Amadou Niangaly
name: Traore, Karim
name: Tolo, Youssouf
name: Fraser, Claire
name: Mahamadou Thera
name: Abdoulaye Djimde
name: Ogobara Doumbo
name: Plowe, Christopher
name: Silva, Joana
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: A file containing Supplementary Tables S1â  S7. Table S1: Samples and respective metadata. Table S2: Genomic DNA: Illumina and PacBio Sequencing Statistics. Table S3: Assembly characteristics for 12 Malian samples generated by Sprai and Celera assemblers. Table S4: Exon 1 var sequences recovered with ETHA compared to raw var-like sequences extracted directly from assemblies. Table S5: Percent of extracted sequence absent from the ETHA output. Table S6: Comparison of PfEMP1 constitutive domains reconstructed from 12 samples to the reference 3D7. Table S7: Average percent (%) amino acid identity within PfEMP1 constitutive domains. (DOCX 64 kb)
§ 5 Die "Gießkanne" als Gleichheitsproblem - Zur Vereinbarkeit der Energiepreispauschale für Erwerbstätige mit dem allgemeinen Gleichheitssatz
Creators: name: Steinbeck, Luca
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2024

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 22 (2023): Geprägte Freiheit 2023/24
§ 6 Zum Solidaritätszuschlag - München locuta, causa finita?
Creators: name: Pracht, Robert
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2024

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 22 (2023): Geprägte Freiheit 2023/24
§ 7 Gelebte Interdisziplinarität
Creators: name: Reimer, Ekkehart
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2024

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 22 (2023): Geprägte Freiheit 2023/24
§ 8 Juristische Use Cases im LangChain Framework - Untersuchungen im Kontext des OECD-Musterabkommens
Creators: name: Steuer, Katharina
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2024

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 22 (2023): Geprägte Freiheit 2023/24
MOESM10 of Robust, high-productivity phototrophic carbon capture at high pH and alkalinity using natural microbial communities
Creators: name: Sharp, Christine
name: Urschel, Sydney
name: Xiaoli Dong
name: Brady, Allyson
name: Slater, Greg
name: Strous, Marc
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 10: Table S8. Characteristics of the four soda lakes.
Additional file 1: of Towards evidence-based vitamin D supplementation in infants: vitamin D intervention in infants (VIDI) — study design and methods of a randomised controlled double-blinded intervention study
Creators: name: Helve, Otto
name: Viljakainen, Heli
name: Holmlund-Suila, Elisa
name: Rosendahl, Jenni
name: Hauta-Alus, Helena
name: Enlund-Cerullo, Maria
name: Valkama, Saara
name: Heinonen, Kati
name: Räikkönen, Katri
name: Hytinantti, Timo
name: Mäkitie, Outi
name: Andersson, Sture
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Supplementary documentation. Methods described in further detail. (DOCX 520 kb)
§ 9 "Allgemeine" Dogmatik speziell für das Steuerrecht?
Creators: name: Zimmermann, Noah
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2024

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 22 (2023): Geprägte Freiheit 2023/24
§ 10 Der Sach- und Rechtsstoff des Steuerwesens
Creators: name: Teichmann, Moritz
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2024

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 22 (2023): Geprägte Freiheit 2023/24
BAP1 genetic testing among melanoma and cancer-prone families in Sweden
Creators: name: Helgadottir, Hildur
name: Schultz, Karina
name: Lapins, Jan
name: Vassilaki, Ismini
name: All-Eriksson, Charlotta
name: Höiom, Veronica
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: BAP1 genetic testing among melanoma and cancer-prone families in Sweden
MOESM1 of Upgrading syngas fermentation effluent using Clostridium kluyveri in a continuous fermentation
Creators: name: Gildemyn, Sylvia
name: Molitor, Bastian
name: Usack, Joseph
name: Mytien Nguyen
name: Korneel Rabaey
name: Largus Angenent
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology

description: Additional file 1. Media used for syngas fermentation; Media compositions.
MOESM11 of Robust, high-productivity phototrophic carbon capture at high pH and alkalinity using natural microbial communities
Creators: name: Sharp, Christine
name: Urschel, Sydney
name: Xiaoli Dong
name: Brady, Allyson
name: Slater, Greg
name: Strous, Marc
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 11: Figure S3. Design of the flat panel photobioreactor system showing (a) a schematic of the photobioreactor design and media flow pattern (b) a photo of an individual photobioreactor, and (c) a photo of the photobioreactor system in operation.
Local disease control after stereotactic body radiotherapy in patients with neuroendocrine neoplasms: a cohort study
Creators: name: Nygaard, Anneli Dowler
name: Pedersen, Ninna Aggerholm
name: Dam, Gitte Aarøe
name: Knap, Marianne Marquard
name: Tabaksblat, Elizaveta Mitkina
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Cancer

description: Neuroendocrine neoplasms represent a diverse group of malignancies. Anatomic origin, histology and aggressiveness vary extensively, from low-grade tumours with an indolent prognosis to highly aggressive conditions with poor outcome. Surgery, with a curative intent, is the standard of treatment when possible. Other treatment regimens include local treatment, or systemic therapy. The role of radiotherapy in treating neuroendocrine neoplasms is not yet established, but studies indicate that a high rate of local control can be achieved by high-dose radiotherapy. Stereotactic body radiotherapy (SBRT) is high dose of radiation delivered to a small volume. We aimed to investigate the one-year local control rate of SBRT in patients with neuroendocrine neoplasms. Patients with neuroendocrine neoplasms treated with SBRT between 2003 and 2021 were retrospectively identified. Patient characteristics and SBRT-details were collected by review of patient records and the radiotherapy planning charts. All types except for small cell lung cancer and brain metastases were allowed. The prescribed dose was 45–67.8 Gy in three fractions. Progression, both within the target-site and in other sites, was determined based on existing imaging reports. One-year local control rate and systemic control rate was calculated. Descriptive analyses of local response duration, progression-free survival and overall survival were performed. Twenty-one patients were included. The one-year local control rate was 94%. Four of the patients had local progression. All patients receiving SBRT towards their primary tumour (n = 11) had a bronchopulmonary neuroendocrine neoplasm, and a one-year local control rate of 100%. In patients treated at a metastatic target, 80% developed systemic progression but the local control remained high. Our study suggests that SBRT may offer a feasible and effective treatment of neuroendocrine neoplasms in selected cases. SBRT provides long-term local stability and may be useful in treating patients with localised disease not fit for surgery.
Additional file 1: Figure S3. of Anti-tumor effects of everolimus and metformin are complementary and glucose-dependent in breast cancer cells
Creators: name: Ariaans, Gerke
name: Jalving, Mathilde
name: Vries, Emma
name: Jong, Steven
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Plant Biology

description: Uncoupling of the mitochondrial respiration with FCCP after treatment with metformin and everolimus for 48 h. Using the seahorse XF analyzer, the basal OCR and maximal OCR after uncoupling of mitochondrial respiration with FCCP of MCF-7 (A) and MDA-MB-231 cells (B) in response to 48 h of metformin or everolimus treatment was determined. Basal OCR in untreated cells was set at 100% as a reference to which all other mitochondrial respiration values of the same glucose concentration group were correlated. Data are presented as mean ± SD of three different experiments. (PDF 69 kb)
Brain radiotherapy in patients treated for a newly diagnosed primary central nervous system lymphoma: professional practice evaluation in 19 French centers
Creators: name: Thomas-Joulié, Alice
name: Houillier, Caroline
name: Antoni, Delphine
name: Créhange, Gilles
name: Jouglar, Emmanuel
name: Colin, Philippe
name: Benchalal, Mohamed
name: Lang, Philippe
name: Alfonsi, Marc
name: Hamidou, Hadji
name: Coutte, Alexandre
name: Ahrweiller, Flora
name: Dadoun, Nathalie
name: Pointreau, Yohan
name: Ammarguellat, Hanifa
name: Bernier-Chastagner, Valérie
name: Belkacemi, Yazid
name: Vieillot, Sabine
name: Hoang-Xuan, Khê
name: Soussain, Carole
name: Jacob, Julian
name: Feuvret, Loïc
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Neuroscience
Pharmacology
Cancer
Science Policy
Mental Health
Hematology

description: The objective of this study was a multicentric evaluation of professional practices, analyzing the irradiation technique itself and its impact on survival and recurrence sites, in primary central nervous system lymphomas (PCNSLs). We retrospectively analyzed the technical and clinical records of 79 PCNSL patients included in the database of the national expert network for oculocerebral lymphoma (‘LOC’) who were treated with brain radiotherapy as first-line treatment for newly diagnosed primary central nervous system lymphoma between 2011 and 2018. The number of patients treated with brain radiotherapy gradually decreased over time. The heterogeneity of radiotherapy prescriptions was significant, and 55% of them did not comply with published recommendations in terms of irradiation dose and/or volume. The proportion of complete responders to induction chemotherapy treated with reduced-dose radiotherapy increased over time. Partial brain radiotherapy was associated with significantly lower overall survival in univariate analysis. In partial responders to induction chemotherapy, increasing the total dose to the brain >30 Gy and adding a boost to the WBRT induced a trend toward improved progression-free and overall survival. Five recurrences (13%) occurred exclusively in the eyes, all in patients whose eyes had been excluded from the irradiation target volume and including 2 patients without ocular involvement at diagnosis. The visibility of recommendations for prescribing brain radiotherapy for the treatment of newly diagnosed primary central nervous system lymphoma needs to be improved to harmonize practices and improve their quality. We propose an update of the recommendations.
Apoprotein E methylation is correlated with immune microenvironment in hepatocellular carcinoma
Creators: name: Li, Jiao
name: Tian, Shan
name: Liu, Qi
name: Peng, Pailan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: We aimed to evaluate the correlation of apoprotein E (APOE) transcription and its methylation with immune microenvironment in HCC patients. The expression profiles of APOE transcription, APOE methylation, and APOE protein were investigated via comprehensive bioinformatic analyses. After that, the association between the immune activation of HCC and APOE transcription and methylation were analyzed. Finally, the prognostic role and immune correlation of the APOE protein in 92 HCC individuals was determined. Based on data from TCGA, GEO, and ICGC datasets, the APOE mRNA was differentially expressed in HCC tissues compared with normal liver tissues. Further, APOE methylation was down-regulated in HCC tissues compared to normal liver tissues. APOE methylation was negatively correlated with APOE transcription in HCC (r=–0.52, p < 0.0001). Based on APOE methylation, the HCC patients were stratified into hypermethylation and hypomethylation subgroups as they exhibited different immune activation statuses. Further, HCC individuals with APOE hypermethylation had a closer immune correlation than those with hypomethylation. Notably, APOE transcription was associated with weak immune infiltrates and activation. Finally, over-expression of the APOE protein was correlated with better survival outcomes, but not correlated with PD-1 or CTLA4 protein in HCC revealed by immunohistochemistry. APOE methylation had a closer correlation with immune cells than APOE mRNA, indicating that APOE methylation might play an important role in immune regulation in HCC.
MOESM1 of Robust, high-productivity phototrophic carbon capture at high pH and alkalinity using natural microbial communities
Creators: name: Sharp, Christine
name: Urschel, Sydney
name: Xiaoli Dong
name: Brady, Allyson
name: Slater, Greg
name: Strous, Marc
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 1: Table S1. Summary of microbial community composition detected in Deer Lake (DL-M) bioreactors on day 58, 85, 98 and 128 using 16S rRNA gene sequencing. Day 0 microbial mat sample is taken from the initial inoculation. Numbers indicate proportion of reads with a >1% average relative abundance in an OTU compared to all OTUs listed on a per sample basis. Closest cultured relative as determined by BLAST search is shown.
Trends in cost of treatment of lung cancer patients in 2014–2019 in Finland – a descriptive register study
Creators: name: Leskelä, Riikka-Leena
name: Korhonen, Sonja
name: Haavisto, Ira
name: Nuutinen, Mikko
name: Peltonen, Emmi
name: Herse, Fredrik
name: Käkelä, Sari
name: Autere, Anna-Maija
name: Nolvi, Katja
name: Tiainen, Satu
name: Silvoniemi, Maria
name: Junnila, Eeva-Liisa
name: Ahvonen, Jarkko
name: Knuuttila, Aija
name: Koivunen, Jussi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: The aim of this descriptive study is to analyze the cost for the treatment of NSCLC and SCLC patients (2014–2019) in Finland. The primary objective is to understand recent (2014–2019) cost developments. The study is retrospective and based on hospital register data. The study population consists of NSCLC and SCLC patients diagnosed in four out of the five Finnish university hospitals. The final sample included 4047 NSCLC patients and 766 SCLC patients. Cost of the treatment in lung cancer is increasing. Both the average cost of the first 12 months as well as the first 24 months after diagnosis increases over time. For patients diagnosed in 2014, the average cost of the first 24 months was 19,000 €and for those diagnosed in 2015 22,000 €. The annual increase in the nominal 24-month costs was 10.4% for NSCLC and 7.3% for SCLC patients. The average cost per patient has increased annually for both NSCLC and SCLC. Possible explanations to the cost increase are increased medicine costs (especially in NSCLC), and the increased percentage of patients being actively treated.
Additional file 2: Figure S1. of Anti-tumor effects of everolimus and metformin are complementary and glucose-dependent in breast cancer cells
Creators: name: Ariaans, Gerke
name: Jalving, Mathilde
name: Vries, Emma
name: Jong, Steven
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Glucose concentration of cell culture medium during 4 days of metformin treatment. MCF-7 and MDA-MB-231 cells were plated at a concentration of 30.000 (MCF-7) or 80.000 (MDA-MB-231) cells in medium containing 11 mM or 2.75 mM glucose. Additionally, cells were plated in medium containing 2.75 mM glucose and replenished with 2.75 mM glucose every 24 h (2.75 mM glucose replenished). Cells were treated with 5 mM metformin for 4 days. 20 μl medium samples were taken for glucose concentration measurements every day. In the glucose-supplemented condition, this was done after addition of glucose. Data are presented as mean ± SD of three different experiments. (PDF 35 kb)
The BioLymph study – implementing precision medicine approaches in lymphoma diagnostics, treatment and follow-up: feasibility and first results
Creators: name: Smedby, K. E.
name: Wästerlid, T.
name: Tham, E.
name: Haider, Z.
name: Joelsson, J.
name: Thorvaldsdottir, B.
name: Krstic, A.
name: Wahlin, B. E.
name: Foroughi-Asl, H.
name: Karlsson, C.
name: Eloranta, S.
name: Saft, L.
name: Palma, M.
name: Kwiecinska, A.
name: Hansson, L.
name: Österborg, A.
name: Wirta, V.
name: Rassidakis, G.
name: Sander, B.
name: Sonnevi, K.
name: Rosenquist, R.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: The BioLymph study – implementing precision medicine approaches in lymphoma diagnostics, treatment and follow-up: feasibility and first results
Prediction of plan adaptation in head and neck cancer proton therapy using clinical, radiographic, and dosimetric features
Creators: name: Bohannon, D.
name: Janopaul-Naylor, J.
name: Rudra, S.
name: Yang, X.
name: Chang, C. W.
name: Wang, Y.
name: Ma, C.
name: Patel, S. A.
name: McDonald, M. W.
name: Zhou, J.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Cell Biology
Pharmacology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Hematology

description: Because proton head and neck (HN) treatments are sensitive to anatomical changes, plan adaptation (re-plan) during the treatment course is needed for a significant portion of patients. We aim to predict re-plan at plan review stage for HN proton therapy with a neural network (NN) model trained with patients’ dosimetric and clinical features. The model can serve as a valuable tool for planners to assess the probability of needing to revise the current plan. Mean beam dose heterogeneity index (BHI), defined as the ratio of the maximum beam dose to the prescription dose, plan robustness features (clinical target volume (CTV), V100 changes, and V100 > 95% passing rates in 21 robust evaluation scenarios), as well as clinical features (e.g., age, tumor site, and surgery/chemotherapy status) were gathered from 171 patients treated at our proton center in 2020, with a median age of 64 and stages from I-IVc across 13 HN sites. Statistical analyses of dosimetric parameters and clinical features were conducted between re-plan and no-replan groups. A NN was trained and tested using these features. Receiver operating characteristic (ROC) analysis was conducted to evaluate the performance of the prediction model. A sensitivity analysis was done to determine feature importance. Mean BHI in the re-plan group was significantly higher than the no-replan group (p < .01). Tumor site (p < .01), chemotherapy status (p < .01), and surgery status (p < .01) were significantly correlated to re-plan. The model had sensitivities/specificities of 75.0%/77.4%, respectively, and an area under the ROC curve of .855. There are several dosimetric and clinical features that correlate to re-plans, and NNs trained with these features can be used to predict HN re-plans, which can be used to reduce re-plan rate by improving plan quality.
title: A Job-Shop Scheduling Model Using Genetic Algorithm and Giffler Thompson Approach
Creators: name: Bumb, Nikhil Deepak
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2009

description: The major objective of this thesis topic is to study the challenging research subject of job shop scheduling with the intent of optimizing the makespan. The job - shop scheduling problem is one of the hardest combinatorial optimization problems. The main aim of scheduling is an efficient allocation of shared resources like machines, operators or both over time for competing activities.

This research focuses on developing a model for optimizing job shop scheduling problem using genetic algorithm and the Giffler Thompson (priority dispatching rule) technique. Considering different parameters, the model comes up with an appropriate way to schedule the tasks for a job shop in order to minimize the makespan. The model leads to a method of finding out the optimal makespan for a job shop problem by taking into consideration various constraints like the availability of machines, availability of operators, and the possibility of processing back a particular job on the same machine.
Xenoberotha Makarkin, 2017, gen. nov.
Creators: name: Makarkin, Vladimir N.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Berothidae
Xenoberotha

description: Genus Xenoberotha gen. nov.
Type and only species. Xenoberotha angustialata sp. nov.
Diagnosis. May be easily distinguished from other genera of the family by a combination of the following character states: [1] scale-like, short, densely spaced setae on procoxae; [2] forewing very narrow (length/width ratio 4.1); [3] forewing CuA pectinate; [4] outer gradate series of crossveins close, nearly parallel to hind margin.
Remarks. This combination of character states does not occur in any other genus of the family. Condition [4] is characteristic of only this genus in the subfamily.
Etymology. From the Greek xenos [ξένος], strange, unusual, and Berotha, a genus-group name. Gender feminine.
description: Published as part of Makarkin, Vladimir N., 2017, An interesting new genus of Berothinae (Neuroptera: Berothidae) from the early Eocene Green River Formation, Colorado, pp. 594-600 in Zootaxa 4226 (4) on page 595, DOI: 10.11646/zootaxa.4226.4.9, http://zenodo.org/record/265181