cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Essays in economic development: education, child labour and wage inequality
Creators: name: Ahmed, Salma
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis presents four self-contained essays that explore issues that are crucial in improving human well-being in a developing country: improving health, minimising child labour and reducing gender inequality. The analysis is focused on Bangladesh where the prevalence of child labour and gender differences in several domains is still widespread. The first essay aims to examine the gender wage gap along the entire wage distribution into an endowment effect and a discrimination effect, taking into account possible selection into full-time employment. Applying a new decomposition approach to the Bangladesh Labour Force Survey (LFS) datasets of 1999 and 2005, we find that women are paid less than men everywhere on the wage distribution and the gap is higher at the lower end of the distribution. Discrimination against women is the primary determinant of the wage gap. We also find that this gap has widened between 1999 and 2005. The second essay examines whether gender differences in tertiary enrolment rates can be explained by wage premiums in returns from secondary to tertiary education levels. Using LFS data, we find that wage premiums do not have any significant effect on the gender gap in tertiary enrolment rates. We also note that wage premiums in returns from secondary to tertiary education significantly influence tertiary enrolment rates for males but not for females, once additional variables are added. We offer evidence that part of the explanation for low female enrolment in tertiary education is attributable to demographic factors. The third essay investigates whether there is any trade-off between child labour hours and schooling. By drawing on the 2002 dataset of the Bangladesh National Child Labour Survey (NCLS), we find that working hours adversely affect child schooling from the very first hour of work. However, the marginal impact of child labour hours weakens when working hours increase; yet, working hours always negatively affect schooling when we use a non-parametric approach. We find that parents do not have identical preferences towards schooling decisions concerning boys and girls. Both mother and father show a significant preference for educating a female child. The same incentive effect is not found for a male child. These conclusions persist, even after allowing for sample selection in child labour. The fourth essay tests the effect of child labour on child health outcomes in Bangladesh. We use self-reported injury or illness due to work as a general measure of health status. Using NCLS data, we find that child labour is positively and significantly associated with the probability of being injured or becoming ill, once the endogenous relationship between these factors is accounted for. These findings remain robust when we consider child labour hours and restrict our analysis to rural areas. Moreover, the intensity of injury or illness is significantly higher in construction and manufacturing than in other sectors.
Additional file 1 of Discovery of antimalarial drugs from secondary metabolites in actinomycetes culture library
Creators: name: Teklemichael, Awet Alem
name: Teshima, Aiko
name: Hirata, Asahi
name: Akimoto, Momoko
name: Taniguchi, Mayumi
name: Khodakaramian, Gholam
name: Fujimura, Takashi
name: Tokumasu, Fuyuki
name: Arakawa, Kenji
name: Mizukami, Shusaku
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Supplementary Material 1.
Additional file 8: of A pooled analysis of mesenchymal stem cell-based therapy for liver disease
Creators: name: Zhao, Lu
name: Chen, Shanquan
name: Shi, Xiaowei
name: Cao, Hongcui
name: Li, Lanjuan
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Results of sensitivity analyses: TBiL levels. (PDF 54 kb)
Generation of monohormonal INSULIN+ cells from human embryonic stem cells
Creators: name: Schiesser, Jacqueline Victoria
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Human Embryonic Stem Cells (hESCs) are immortal, pluripotent cells derived from the inner cell mass of the pre implantation embryo. These cells have the potential to differentiate into all cell types including insulin producing beta cells, which could provide an alternative to cadaver‐derived islets for the treatment of type 1 diabetes. We have explored the formation of pancreatic progenitor cells and mature β‐cells using hESC reporter lines which express GFP under the control of regulatory sequences from the PDX1 and INSULIN genes respectively. Using serum‐free media, we have found that specific combinations of factors applied in a sequential fashion result in the formation of a pancreatic precursor population, which can be further differentiated to hormone expressing cells. These endocrine cells have been shown to be a heterogeneous population that contains a substantial population of INSULIN expressing cells that do not express either glucagon or somatostatin, of which a subpopulation expresses NKX6.1. An INSULINGFP/w hESC reporter line was further modified by the addition of a luciferase transgene under the control of an EF1α promoter, which allowed for in vivo imaging of transplanted INSULIN expressing cells. Differentiated Tg‐EF1αLuc.INSULINGFP/w cells were sorted based on INSULIN‐GFP expression, and transplanted under the kidney capsule of immunocompromised mice and assessed for the retention of INSULIN‐GFP+ cells. It was found that the transplanted INSULIN+ cells had the ability to form monohormonal endocrine cells of three different lineages. Additionally it was seen that persisting INSULIN+ cells co‐expressed transcription factors associated with beta‐cell maturity, such as NKX6.1 and MAFA.
Strengthening of concrete structures using carbon fibre reinforced polymers and cement-based adhesives
Creators: name: Hashemi, Siavash
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: The research project conducted in this study concerns the investigation of the application of cement-based adhesives in CFRP strengthening of reinforced concrete members. The results demonstrate that mineral-based adhesives can provide the desired matrices for CFRP reinforcement. The literature review covers the background of CFRP application with conventional techniques. The bond characteristics of CFRP to concrete substrate, the flexural performance of retrofitted RC beams, and the failure modes at normal temperature are discussed. The guidelines for and numerical approaches to CFRP application are reviewed. Current studies of CFRP application at high temperature and related studies on the application of cement-based adhesive as bonding agent are investigated. The experimental work on the bond characteristics of CFRP material to concrete substrate using cement-based adhesive includes tests on single-lap shear. Results show that the cementitious adhesive can provide a reliable matrix for CFRP textiles to achieve certain bond stresses comparable to what can be achieved using conventional inorganic adhesives. The failure mode is debonding through the CFRP-mortar interface. The bond-slip relationship was extracted and later applied in finite element analysis. The experimental work on retrofitting of RC beams using cementitious adhesive showed that CFRP textile is the most compatible option with this new type of adhesive. The CFRP textile can improve the flexural ultimate strength of RC beams by 35%. The failure mode was intermediate debonding, similar to that achieved by using epoxy as reported in the research literature. A new type of anchorage was utilised for CFRP application using cementitious adhesive, which improved the ultimate capacity by 42%. The failure mode was concrete crushing on top, inferring that the full possible capacity of the beam was utilised. The experimental work pursued an investigation of flexural performance of retrofitted beams at high temperature. The results show that the retrofitted RC beam with cement-based adhesive had a considerable high temperature endurance compared to the specimens with epoxy. The failure temperature was 844°C. The proposed strengthening technique is therefore a reliable method for structures at high risk of fire exposure. The failure mode is intermediate debonding within a high moment region. Finite element analysis (FEA) was conducted to simulate and gain a better understating of the performance of retrofitted members. There was a good correlation between the empirical results and the FE analysis. Furthermore, FEA was used to simulate the performance of a retrofitted RC beam under fire, and to predict the fire endurance and failure mode of the beam.
Back contact dye-sensitized solar cells
Creators: name: Fu, Dongchuan
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Abstract The objective of this work was to develop back-contact dye-sensitized solar cells (back-contact DSCs). These solar cells comprise working and counter electrodes on the same side of the dye-sensitized TiO2 film, in either an interdigitated or a coplanar configuration. In the novel solar cell architectures, transparent conductive electrodes can be replaced by metal-based electrodes. This facilitates the use of cheaper and more conductive electrode materials in dye-sensitized solar cells. We presented in Chapter 1 an introduction to solar energy and solar cells including dye-sensitized solar cell, followed by a literature review on relevant research. In Chapter 2, we summarized experimental details, including materials, reagents, general DSC fabrication methods, and DSC characterization techniques. In Chapter 3, we described the first step in the fabrication of interdigitated back-contact DSCs (IBCDSCs) - the laser ablation process to produce interdigitated electrodes. Successfully patterned electrodes are essentially required to produced working IBCDSCs. In Chapter 4, we developed a pulsed-current electrochemical deposition method for producing Pt catalytic coatings in IBCDSCs. The method was found also suitable for platinizing counter electrodes for conventional DSCs. In Chapter 5 and chapter 6, we discussed the fabrication of interdigitated and coplanar back-contact DSCs (IBCDSCs and CBCDSCs). We achieved the highest conversion efficiencies of 3.6 % and 4.6 % on the two devices measured under simulated AM1.5G sunlight. All the results were compared to the performance of conventional DSCs using identical TiO2, dyes and electrolytes. In Chapter 7, we described three-terminal tandem DSCs comprising conventional TiO2 photoelectrodes and IBCDSCs. Nearly 10 % improvements in the photocurrent and conversion efficiencies were shown by using the IBCDSCs as back subcells. The final chapter drew general conclusions and proposed outlook of the future work for the present research.
Structure and inhibitors of S. aureus HPPK - a folate pathway enzyme
Creators: name: Chhabra, Sandeep
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Folate is an essential vitamin (vitamin B9) that is required for many one-carbon transfer reactions and is a critical precursor for the biosynthesis of purines, pyrimidines, and amino acids. Folate is a dietary requirement for man and animals. However bacteria, parasites and plants can synthesize folate de novo using enzymes of the folate biosynthesis pathway. Thus folate biosynthesis remains a key target for antimicrobial therapy as exemplified by the sulfa drugs that date back to the 1940s, acting on the enzyme DHPS. HPPK, like other enzymes of the folate biosynthesis pathway, is absent in man and therefore is a potential drug target for the development of antimicrobial agents. Increasing rates of drug resistance to current antibiotics is a serious problem, due to the rapid adaptation of microorganisms to our chemical interventions. Because HPPK is not the target of any existing antibiotic, it is attractive for the development of new antibiotics against resistant strains. The dearth of substrate-site inhibitors for HPPK observed in the literature reflects a combination of difficult pterin-like chemistry and a paucity of commercially available pterin-like molecules, compounded by a highly specific substrate site. This knowledge gap presents interesting research opportunities. Herein, the first structural and biophysical data on 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (SaHPPK), from the pathogen Staphylococcus aureus is presented. HPPK catalyses the pyrophosphoryl transfer from the cofactor (ATP) to the pterin substrate (6-hydroxymethyl-7,8-dihydropterin, HMDP). The expression, purification and protein stability was optimised to provide high yields for both screening and crystallisation experiments. A combination of fragment and in silico based methods was adopted to identify small molecule inhibitors of the SaHPPK enzyme.
Additional file 1: of Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
Creators: name: Hoyles, Lesley
name: Snelling, Tom
name: Umlai, Umm-Kulthum
name: Nicholson, Jeremy
name: Carding, Simon
name: Glen, Robert
name: McArthur, Simon
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S1. Effects of propionate treatment (1 μM, 24 h) upon mRNA expression of BBB-related genes in hCMEC/D3 cells, grouped in broad functional categories. Gene names listed in bold were significantly regulated compared to untreated cells (PFDR < 0.05). (PDF 381 kb)
Additional file 9: of A pooled analysis of mesenchymal stem cell-based therapy for liver disease
Creators: name: Zhao, Lu
name: Chen, Shanquan
name: Shi, Xiaowei
name: Cao, Hongcui
name: Li, Lanjuan
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Visualized results of publication bias of TBiL. (PDF 133 kb)
The Significance of Ratifying International Laws and  Resolutions on Anti-Corruption in Uzbekistan:  Economic-Political and Socio-Legal Mechanisms
Creators: name: Research advisor:, MUSTAFAYEV J. SH.
name: Boliyev Ravshan Akmal o'g'li
Publisher: name: Zenodo
Year: 2024

description: Abstract:  The  article  is  devoted  to  an  analysis  of  legal  acts  of  the  Republic  of Uzbekistan  on  counteraction  against  corruption.  The  article  provides  the classification  and  review  of  the  anti-corruption  legislation  of  Uzbekistan.  The article  also  deliberates  about  the  measures  taken  by  Uzbekistan  to  implement relevant international legal standards into the national legal system
Additional file 2: of Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
Creators: name: Hoyles, Lesley
name: Snelling, Tom
name: Umlai, Umm-Kulthum
name: Nicholson, Jeremy
name: Carding, Simon
name: Glen, Robert
name: McArthur, Simon
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Figure S1. Persistence of the protective effect of propionate upon LPS-induced barrier disruption across different doses. (a) Assessment of the paracellular permeability of hCMEC/D3 monolayers to 70 kDa FITC–dextran following treatment for 24 h with 1, 10 or 100 μM propionate, with or without inclusion of 50 ng/ml LPS for the last 12 h of incubation; data are mean ± SEM, n = 3 independent experiments. (b) Trans-endothelial electrical resistance of hCMEC/D3 monolayers following treatment for 24 h with 1, 10 or 100 μM propionate, with or without inclusion of 50 ng/ml LPS for the last 12 h of incubation; data are mean ± SEM, n = 3 independent experiments. (PDF 341 kb)
Carnet nº 2, commencé à Vienne (p. 91)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 14-10-1928
Additional file 1 of Feature selection with interactions in logistic regression models using multivariate synergies for a GWAS application
Creators: name: Xu, Easton
name: Qian, Xiaoning
name: Yu, Qilian
name: Zhang, Han
name: Cui, Shuguang
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Marine Biology
subject: Virology

description: Some useful lemmas and the proofs of Theorems 1 and 5. (PDF 89 kb)
MOESM1 of Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT
Creators: name: Simonis, Fabienne
name: Barbas, Carmen
name: Artigas-RaventĂłs, Antonio
name: Canet, Jaume
name: Determann, Rogier
name: Anstey, James
name: Hedenstierna, Goran
name: Hemmes, Sabrine
name: Hermans, Greet
name: Hiesmayr, Michael
name: Hollmann, Markus
name: Jaber, Samir
name: Martin-Loeches, Ignacio
name: Mills, Gary
name: Pearse, Rupert
name: Putensen, Christian
name: Schmid, Werner
name: Severgnini, Paolo
name: Smith, Roger
name: Treschan, Tanja
name: Tschernko, Edda
name: Vidal Melo, Marcos
name: Wrigge, Hermann
name: Abreu, Marcelo
name: Pelosi, Paolo
name: Schultz, Marcus
name: Neto, Ary
Publisher: name: figshare
Year: 2018
Subjects: Biophysics
Space Science
Medicine
Biological Sciences not elsewhere classified
Science Policy
Mental Health
Hematology

description: Additional file 1. List of PRoVENT network collaborators. Table S1 Univariable analysis of factors associated with in-hospital mortality in patients without ARDS receiving mechanical ventilation. Table S2 Analysis of factors associated with ICU mortality in patients without ARDS receiving mechanical ventilation. Table S3 Analysis of factors associated with ICU mortality in patients without ARDS receiving mechanical ventilation considering driving pressure in the model instead of maximum airway pressure. Table S4 Analysis of factors associated with in-hospital mortality in patients without ARDS receiving mechanical ventilation considering driving pressure in the model instead of maximum airway pressure. Table S5 Analysis of factors associated with in-hospital mortality in patients without ARDS receiving mechanical ventilation considering maximum airway pressure in the subset of 343 patients in whom driving pressure could be reliably measured. Table S6 Analysis of factors associated with ICU mortality in patients without ARDS receiving mechanical ventilation considering maximum airway pressure in the subset of 343 patients in whom driving pressure could be reliably measured. Figure S1 Odds ratio of ICU mortality according to increases in one standard deviation of Pmax and in the patients at risk and not at risk of ARDS.
Additional file 3: of Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
Creators: name: Hoyles, Lesley
name: Snelling, Tom
name: Umlai, Umm-Kulthum
name: Nicholson, Jeremy
name: Carding, Simon
name: Glen, Robert
name: McArthur, Simon
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Figure S2. Protective effects of propionate against LPS-induced barrier disruption in primary human brain microvascular endothelial cells (HBMEC). (a) Assessment of the paracellular permeability of HBMEC monolayers to 70 kDa FITC–dextran following treatment for 24 h with 1 μM propionate, with or without inclusion of 50 ng/ml LPS for the last 12 h of incubation; data are mean ± SEM, n = 3 independent experiments. (b) Trans-endothelial electrical resistance of HBMEC monolayers following treatment for 24 h with 1 μM propionate, with or without inclusion of 50 ng/ml LPS for the last 12 h of incubation; data are mean ± SEM, n = 3 independent experiments. (PDF 321 kb)
Additional file 4: of Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
Creators: name: Hoyles, Lesley
name: Snelling, Tom
name: Umlai, Umm-Kulthum
name: Nicholson, Jeremy
name: Carding, Simon
name: Glen, Robert
name: McArthur, Simon
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S2. Effects of propionate treatment (1 μM, 24 h) upon mRNA expression of antioxidant system-related genes in hCMEC/D3 cells. Gene names listed in bold were significantly regulated compared to untreated cells (PFDR < 0.05). (PDF 385 kb)
Additional file 1: of Facial soft tissue changes after nonsurgical rapid maxillary expansion: a systematic review and meta-analysis
Creators: name: Huang, Jing
name: Li, Cui-Ying
name: Jiang, Jiu-Hui
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Table S1. Articles excluded after full text reading and the reasons for exclusion. (DOC 36Â kb)
Additional file 1: of Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice
Creators: name: Pan, Fengwei
name: Zhang, Liying
name: Li, Min
name: Hu, Yingxin
name: Zeng, Benhua
name: Yuan, Huijuan
name: Zhao, Liping
name: Zhang, Chenhong
Publisher: name: figshare
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary results about summary of sequencing on the V3-V4 region of 16S rRNA gene. (DOCX 13Â kb)
Additional file 5: of Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
Creators: name: Hoyles, Lesley
name: Snelling, Tom
name: Umlai, Umm-Kulthum
name: Nicholson, Jeremy
name: Carding, Simon
name: Glen, Robert
name: McArthur, Simon
Publisher: name: figshare
Year: 2018
Subjects: Biochemistry
Medicine
Molecular Biology
Neuroscience
Pharmacology
Chemical Sciences not elsewhere classified
Cancer
Mental Health

description: Figure S3. Effects of propionate upon expression and activity of typical cerebromicrovascular efflux transporter systems. (a) Surface expression of BCRP, LRP-1 and P-glycoprotein on control and propionate-treated (1 μM, 24 h) hCMEC/D3 cells (black, control, red, propionate), data are representative of three independent experiments. (b) Median fluorescence intensity of surface expression of BCRP, LRP-1 and P-glycoprotein on control and propionate-treated (1 μM, 24 h) hCMEC/D3 cells; data are mean ± SEM, n = 3 independent experiments. (c) Lack of stimulatory effect of propionate upon BCRP, data are mean ± SEM, n = 4. (d) Lack of inhibitory effect of propionate upon stimulated ATP-dependent activity of BCRP, data are mean ± SEM, n = 4. (e) Lack of stimulatory effect of propionate upon P-glycoprotein, data are mean ± SEM, n = 4. (f) Lack of inhibitory effect of propionate upon stimulated ATP-dependent activity of P-glycoprotein, data are mean ± SEM, n = 4. (PDF 437 kb)
Pierre de Truchis
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (9 pages). Autres destinataires : Jean-Claude Alvarez, Dominique Mathez, Damien Le Dû, Christian Perronne, Jean-Claude Melchior
description: Pièce jointe : article de Akil Jackson, et al. "Plasma and Intracellular Pharmacokinetics of Darunavir/ Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals"
Dietary intervention among patients with type 2 diabetes mellitus: an e-approach
Creators: name: Ramadas, Amutha
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: myDIDeA was a 12-months two-armed randomised controlled trial conducted in three tertiary public hospitals in Klang Valley, Malaysia. The primary outcome was the Dietary Knowledge, Attitude and Behaviour (DKAB) score, while the secondary outcomes included measures of food intake, anthropometry measurements, blood pressure and resting heart rate, some blood biomarkers and the Dietary Stages of Change (DSOC) score. The study was designed according to the recommendations of the CONSORT statement for randomised trials of non-pharmacologic treatment. The study commenced in November 2009 after obtaining the ethical approvals from relevant authorities, and the trial has been registered with Clinicaltrials.gov (NCT01246687). After being screened for eligibility, 128 patients with Type 2 Diabetes Mellitus (T2DM) from the outpatient clinics at these hospitals were recruited with informed consent, and then randomised into the e-intervention (n=66) or the control (n=62) group. The e-intervention group received an intensive six-month dietary intervention through the study website, which was developed based on various established guidelines and recommendations but personalised according to the participants’ DSOC, in addition to the usual standard treatment at the outpatient clinics. In contrast, the control group continued their usual standard treatment for patients with T2DM in the hospitals. Data were collected at baseline, six months post-intervention and at 12 months follow-up. A pre-tested and validated questionnaire was used for this purpose. The anthropometry measurements, blood pressure and resting heart rate were measured at data collection, while details on the blood biomarkers were obtained from the hospital medical records. All data were analysed with IBM® PASW® Statistics 17.0. On average, each participant logged into the website once a week and spent 11 minutes at the website per visit. myDIDeA was found to be a successful intervention programme to improve the overall DKAB score, due to the improvement in the knowledge and attitude sub-domains. Additionally, the intervention programme also successfully improved the DSOC score of the intervention group, which suggests participants were also making small but significant progress in changing their dietary behaviour. Some additional improvements in diet quality (reduction in carbohydrate and protein intake), glycaemic control and total cholesterol were also detected. myDIDeA is one of few web-delivered dietary interventions for patients with chronic disease. The reach, flexibility, accessibility and conversion of established guidelines into a more user-friendly format have contributed to the success of this intervention programme. Future related studies are suggested to emphasise on the interactivity, familiarise the participants with the system prior to the intervention, encourage self-monitoring and built the intervention on a strong theoretical background.
title: 01_0323
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Does information about minimization tactics alter observers' expectations of sentencing?
Creators: name: Luke, Timothy J.
name: Alceste, Fabiana
Publisher: name: OSF Registries
Year: 2016

description: In a previous study, we found that minimization tactics influenced people's sentencing expectations such that they believed a suspect would be treated more leniently if they confessed. This effect persisted in the face of a warning that police could not guarantee leniency in exchange for a confession, and it occurred even though participants were generally aware that interrogators did not directly promise leniency in exchange for a confession when they read a transcript that contained minimization tactics.

This study is designed as a replication and extension of our previous study (Study 1). As in Study 1, we will manipulate the tactics used by the interrogator in the transcripts read by the participants. We will also manipulate whether the participant receives a corrective message about police promises of leniency (and the position of that correction). Unlike Study 1, we will additionally manipulate whether participants are given a description of the tactic of minimization (and the position of that informative message).

We think observers might be prone to a fundamental attribution error, such that even when they know minimization is merely a tactic to convince suspects to confess, they may nevertheless not adjust their sentencing expectations to account for this fact.
Two-dimensional spatiotemporal complexity in dual-delayed nonlinear feedback systems: Chimeras and dissipative solitons
Creators: name: Brunner, Daniel
name: Penkovsky, Bogdan
name: Levchenko, Roman
name: Schöll, Eckehard
name: Larger, Laurent
name: Maistrenko, Yuri
Publisher: name: Technische Universität Berlin
Year: 2018
Subjects: subject: 530 Physik
subject: dissipative soliton
subject: numerical simulation
subject: chimeras
subject: delay systems

description: This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Chaos 28, 103106 (2018) and may be found at https://doi.org/10.1063/1.5043391.
description: We demonstrate for a photonic nonlinear system that two highly asymmetric feedback delays can induce a variety of emergent patterns which are highly robust during the system’s global evolution. Explicitly, two-dimensional chimeras and dissipative solitons become visible upon a space-time transformation. Switching between chimeras and dissipative solitons requires only adjusting two system parameters, demonstrating self-organization exclusively based on the system’s dynamical properties. Experiments were performed using a tunable semiconductor laser’s transmission through a Fabry-Pérot resonator resulting in an Airy function as nonlinearity. Resulting dynamics were bandpass filtered and propagated along two feedback paths whose time delays differ by two orders of magnitude. An excellent agreement between experimental results and the theoretical model given by modified Ikeda equations was achieved. Photonic delay systems are of astonishing diversity and have created a rich field of fundamental research and a wide range of applications. Under a transformation from time into pseudo-scape, their basic architecture makes them equivalent to ring networks with perfectly-symmetric coupling. For the first time we extend this spatiotemporal analogy in experiments by adding a second delay, 100 times the length of the first delay line. Nonlinearity is provided by a tunable semiconductor laser traversing a Fabry-Pérot resonator. Visualized in 2D-space, we show the temporal evolution of different chimeras and dissipative solitons. Experimental results excellently agree with numerical simulations of the double-delay bandpass Ikeda equation. Based on the attractors of multiple fixed-point solutions, we provide insight into the mechanism structuring the system’s dynamics.
title: ÐÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½ÑÐ¹ ÑÑÑÐ¸Ð·Ð¼ ÐºÐ°Ðº ÑÐ°ÐºÑÐ¾Ñ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð²Ð½ÐµÑÐ½ÐµÐ¿Ð¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸Ð½ÑÐµÑÐµÑÐ¾Ð² Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²Ð°
title: Ð¼Ð¾Ð½Ð¾Ð³ÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ°ÑÐ²ÐµÐµÐ²ÑÐºÐ°Ñ, ÐÐ½Ð½Ð°
name: ÐÐ²ÑÐµÐµÐ², ÐÐ»Ð°Ð´Ð¸Ð¼Ð¸Ñ
name: ÐÐ¾Ð³Ð¾Ð´Ð¸Ð½, Ð¡ÐµÑÐ³ÐµÐ¹
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2023
Subjects: Ð²Ð½ÐµÑÐ½ÑÑ Ð¿Ð¾Ð»Ð¸ÑÐ¸ÐºÐ°

description: Ð Ð¼Ð¾Ð½Ð¾Ð³ÑÐ°ÑÐ¸Ð¸ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð¾Ð² Ðº ÑÑÐµÑÐµ Ð¼ÐµÐ¶Ð´ÑÐ½Ð°ÑÐ¾Ð´Ð½Ð¾Ð³Ð¾ ÑÑÑÐ¸Ð·Ð¼Ð° ÐºÐ°Ðº ÑÐ°ÐºÑÐ¾ÑÐ° Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð²Ð½ÐµÑÐ½ÐµÐ¿Ð¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸Ð½ÑÐµÑÐµÑÐ¾Ð² Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ² Ð¸ Ð¿Ð¾Ð¸ÑÐºÐ° Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ ÑÑÐµÐ½Ð´Ð¾Ð² Ð¸Ñ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ Ð³Ð»Ð¾Ð±Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸, ÑÐ¾ÑÑÐ° Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÑÐ°ÐµÐºÑÐ¾ÑÐ¸Ð¹ Ð¸ ÑÐ¸ÑÑÐ¾Ð²Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ ÑÑÐµÐ´Ñ. ÐÐ¾Ð½Ð¾Ð³ÑÐ°ÑÐ¸Ñ Ð¾ÑÑÐ°Ð¶Ð°ÐµÑ Ð¸Ð½ÑÐµÑÐµÑ Ð½Ð°ÑÑÐ½Ð¾Ð¹ Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ðº Ð²Ð¾Ð¿ÑÐ¾ÑÐ°Ð¼ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° ÑÑÐ°Ð½ÑÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¸ ÐºÐ°Ð½Ð°Ð»Ð¾Ð² Ð¸ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð¸ Ð¿Ð¾Ð·Ð¸ÑÐ¸Ð¾Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð²Ð½ÐµÑÐ½ÐµÐ¿Ð¾Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸Ð½ÑÐµÑÐµÑÐ¾Ð² Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ² Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Â«ÑÐ°Ð½ÐºÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¾Ð³ÑÐ°Ð½Ð¸ÑÐµÐ½Ð¸Ð¹Â» Ð¸ Ð¾Ð´Ð½Ð¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ Ð·Ð½Ð°ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¿ÑÐ¾ÑÐµÑÑÐ¾Ð² Ð² Ð¼Ð¸ÑÐ¾Ð²Ð¾Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐ¸ÐºÐµ.
A SYSTEMATIC RESEARCH REVIEW ON TEACHERS PROFESSIONAL DEVELOPMENT
Creators: name: Dr. Kotra Balayogi
Publisher: name: Zenodo
Year: 2024

description: Teaching profession is a greatest noblest occupation and quality of teachers determines the standard of student performance, success, achievement, etc. As educators one should be always ready for challenges and changes to upgrade skills and knowledge, can be made possible only through continuous Professional Development (PD) and he/she meeting the requisite qualification but lacks skills and no opportunity to update knowledge base cannot be called a qualified or trained teacher. A qualified teacher should be consistently evolving for better performance and appraisal. In this article we will be discussing about the different areas where teacher educators can enhance their professional competencies in order to transact quality education to learners and how improperly qualified educators affect the 21st century educational system.
title: Image-based multispectral flow cytometry – a new analytical approach for fast and efficient pollen determination
Creators: name: Walther, Franziska
name: Dunker, Susanne
name: Janke, Martina
name: Campbell, Selina
name: Erler, Silvio
name: Hornick, Thomas
name: Rakosy, Demetra
name: Harpole, Stan
name: Friedrich, Elsa
name: Schroeder, Annette
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2025
Subjects: subject: 630

description: Julius-Kühn-Archiv, vol. 481Hazards of pesticides to bees, 16th International Symposium of the ICP-PR Bee Protection Group, - Proceedings -; 15th - 17th October, 2024; Sevilla (Spain), p. 64
Additional file 1: of Tumor-infiltrating mast cells predict prognosis and gemcitabine-based adjuvant chemotherapeutic benefit in biliary tract cancer patients
Creators: name: Bo, Xiaobo
name: Wang, Jie
name: Suo, Tao
name: Ni, Xiaoling
name: Liu, Han
name: Shen, Sheng
name: Li, Min
name: Wang, Yueqi
name: Liu, Houbao
name: Xu, Jiejie
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Table S1. Association between CD8+ T cells infiltration and patient characteristics. (DOC 64 kb)
Non-parametric estimation of forecast distributions in non-linear, non-gaussian state space models
Creators: name: Ng, Jason Wei Jian
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Non-Gaussian time series variables are prevalent in the economic and finance spheres, with state space models often employed to analyze such variables and, ultimately, to produce forecasts. A review of the relevant literature reveals that existing methods are characterized by a reliance on (potentially incorrect) parametric assumptions and are often computationally expensive. The primary aim of this thesis is to develop a non-parametric approach to forecasting - within the state space framework - with computational ease an important focus. With a view to capturing all relevant information about the likely future values of the variable of interest, the approach is used to produce non-parametric estimates of the full forecast distribution over any time horizon. Simulation experiments are used to document the accuracy of the non-parametric method relative to both correctly and incorrectly specified parametric alternatives, in a variety of relevant settings. Applying a range of methods for evaluating and comparing distributional forecasts, the non-parametric method is shown to perform significantly better, overall, than misspecified parametric alternatives while remaining competitive with correctly specified parametric estimators. Focus is then given to the development of a new non-Gaussian state space model for observed realized volatility from which estimates of forecast distributions of future volatility are produced using the non-parametric method. In an empirical illustration, the non-parametric method is used to produce sequential estimates of the out-of-sample one-step-ahead forecast distribution of realized volatility on the S&P500 index during the recent financial crisis. A resampling technique for measuring sampling variation in an estimated forecast distribution is also demonstrated. The proposed filtering algorithm is further extended to cater, in particular, for multi-step-ahead forecasting and multivariate systems. A simulation-based version of the algorithm is also illustrated, with the algorithm in this form seen to be a computationally efficient alternative to existing particle filtering algorithms.
title: 03_0244
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 1 of Behaviour change interventions to improve physical activity in adults: a systematic review of economic evaluations
Creators: name: Barrett, Stephen
name: Begg, Stephen
name: Lawrence, Jack
name: Barrett, Gabrielle
name: Nitschke, Josh
name: O’Halloran, Paul
name: Breckon, Jeff
name: Pinheiro, Marina De Barros
name: Sherrington, Catherine
name: Doran, Chris
name: Kingsley, Michael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1
A fragment-based approach to the identification of novel ketopantoate reductase inhibitors
Creators: name: Vom, Amelia
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Pantothenate (Vitamin B5) is a key precursor to coenzyme A, an essential cofactor for fatty acid biosynthesis and other metabolic processes. The pathway for pantothenate biosynthesis is only present in microorganisms and plants, suggesting it may be a target for developing novel antimicrobial agents. Ketopantoate reductase (KPR), a 34 kDa protein, is a key enzyme on this pathway, catalysing the NADPH-dependent reduction of ketopantoate to pantoate. In this study, a fragment-based lead design (FBLD) approach was used to identify small molecule inhibitors of KPR. The expression and purification of labelled and unlabelled KPR was optimised to give high yields suitable for screening and kinetic studies. NMR based screening of 500 fragments using STD-NMR identified 47 hits that were validated by 1H/15N-HSQC NMR, resulting in 14 confirmed fragment hits, correlating to a hit rate of 3%. These hits were assessed for inhibitory activity, with 4 compounds showing an IC50 < 500 μM. The fragment hits were prioritised based on ligand efficiency (the quality of binding interactions between the fragment and target protein) and tractability for synthetic elaboration and derivatisation. Preliminary SAR was established for three series by testing simple analogues of the initial hit. Further analogues based on the scaffolds - sulfonamide, thienopyrrole and phenylthiophene were designed and synthesised to optimise binding to the active site and improve the potency. Binding locations of the fragment hits were identified using 1H/15N-HSQC NMR based on the assigned backbone resonances of E. coli KPR. This thesis also describes the risks of false positives in fragment-based identification of KPR inhibitors. The lead series were identified to be inhibiting through a non-specific mechanism, which was confirmed to be aggregation based, by comparison with literature studies of aggregating compounds. As a result, an NMR-based fragment screening approach and enzyme assay was developed to overcome many of the challenges posed by false positives. Post elimination of false positives, a number of fragment hits has been confirmed to inhibit KPR activity in an in vitro assay.
Additional file 1: of No difference in the functional improvements between unilateral and bilateral total knee replacements
Creators: name: Huang, Yu-Hao
name: Lin, Chin
name: Yang, Jia-Hwa
name: Lin, Leou-Chyr
name: Mou, Chih-Yuan
name: Chiang, Kwo-Tsao
name: Lee, Man-Gang
name: Chang, Hsien-Feng
name: Chang, Hsueh-Lu
name: Su, Wen
name: Yeh, Shih-Jen
name: Chang, Hung
name: Wang, Chih-Chien
name: Su, Sui-Lung
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology

description: Table S1. Characteristics between patients who loss to follow-up or not. (DOCX 35Â kb)
INVESTIGATION AND COMPARISON OF OPTICAL PROPERTIES OF NICKEL NANOWIRES AND NICKEL THIN FILM USING HE-NE LASER
Creators: name: Arya, Sandeep
name: Kaur, Manpreet
name: Kumar, Ashok
name: Lehana, Parveen
Publisher: name: figshare
Year: 2018
Subjects: classificationCode: 400607
subject: Signal processing

description: Ni nanowires are synthesized by template based electrochemical technique. A commercially available filter membrane of alumina anodic oxide (AAO) is used for the fabrication of nanowires. AAO membrane supported on copper substrate yields better hexagonal nanowires. Morphological studies of nanowires are carried out using scanning electron microscopy (SEM). The analysis shows the fabrication of vertical 100 nm nanowires. The optical properties using He-Ne laser light have been studied. In order to study the reflection of laser light from the substrate containing Ni nanowires a high resolution camera was employed. These images were further processed using image processing technique. To nullify the effect of the surrounding optical sources, these images were desaturated. The analysis of the results shows that at different angles the reflection of light from substrate containing Ni nanowires shows a regular pattern as compared to Ni thin film. Peak is observed when laser is incident at right angle to the plane of the sample containing Ni nanowires.