cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Trade liberalization and political control: Regulating trade between the People's Republic of China and the Republic of China on Taiwan.
Creators: name: Chen, Chun-Shan.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Political Science, International Law and Relations.

description: Trade relations between the People's Republic of China ("PRC") and the Republic of China ("ROC") on Taiwan are complex because of their incompatible trade regimes, diverse political perspectives, different stages of economic development, and contrasting ideologies for legal arrangements. The central theme of this study is to propose solutions to regulate such complex trade relations. It also provides an analysis with respect to the substantive and procedural arrangements of a trade agreement between the PRC and the ROC. The study is divided into six chapters. Chapter one presents a factual background of PRC-ROC political and economic relations. Chapter two examines the main inconsistencies of PRC-ROC trade and economic regimes, which include problems such as the conflicting perspectives between trade liberalization and political control, the incompatibilities between centrally-planned and market economies, and the functions and limitations of legal arrangements for trade between both governments. Chapters three and four deal with the issues of trade restrictions for national security and foreign policy purposes as well as the prevention of market disruption. Chapter five discusses the impacts and applications of multilateral, regional and bilateral mechanisms for arranging PRC-ROC trade relations. Chapter six focuses on the procedural arrangements for concluding multilateral and bilateral trade agreements between the PRC and the ROC. This study concludes that a liberal perspective is an essential approach to maximize the economic benefits of PRC-ROC trade. Such an approach, however, may face difficulties such as governmental interventions which are sometimes inevitable for national security and foreign policy concerns. This study further indicates that political controls on trade activities between both governments should have limitations in order not to impair their own interests. On a long-term basis, PRC-ROC trade relations need to be liberalized and legalized. This study shows that the GATT system is the most appropriate mechanism in achieving the above purpose. Another option, which is available in case the GATT system breaks down, is the setting up of a regional or bilateral program to promote the regional or bilateral trade interests of the PRC and the ROC. It is hopeful that this study may serve two purposes. On a concrete level, it could provide a case study on the regulatory policies of PRC-ROC trade relations and propose alternative structures for future development. On a more general level, it could contribute to a better understanding of the nature and scale of the problems involved in the effort of linking two different types of economies, compounded by many aspects of conflicting political, economic, and legal characteristics.
6 maanden Wikipedian-in-Residence KB en NA, Voortgang & vooruitblik, 01-04-2014
Creators: name: Janssen, Olaf
name: Kranen, Hay
name: de Haan, Tim
Publisher: name: Zenodo
Year: 2024
Subjects: National Archives of the Netherlands
GLAMwiki
Wikimedia
Wikipedia
KB, national library of the Netherlands
Koninklijke Bibliotheek
Hay Kranen
Olaf Janssen
Tim de Haan
Nationaal Archief
progress report
Wikipedian in Residence
GLAM

description:  Update over de voortgang en resultaten na 6 maanden Wikipedian-in-Residence project van de Koninklijke Bibliotheek en het Nationaal Archief.
Perceptions and experiences of Mexican graduate learners studying in the United States: A basic interpretive qualitative study
Creators: name: Gutierrez Estrada, Maria Rebeca
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Sociology, Ethnic and Racial Studies.
subject: Education, Higher.

description: The present study explores the language, cultural and social perceptions and experiences of eight Mexican instructors pursuing graduate degrees in the southwestern U.S. Identity and power relations in academia are also explored. The main research questions are: (1) How do Mexican, Spanish-speaking university instructors pursuing graduate degrees in English in the U.S. perceive their language, academic, social and cultural experiences? (2) How do they cope with the linguistic, social, and cultural demands of their new environment? (3) How do they perceive their identity(ies)? (4) In what ways does their relationship with their advisor, professors, peers, impact their life in academia and in the U.S.? The findings of this basic interpretive qualitative study revealed that the participants' identities as multiple, dynamic, diverse, and changing guided them in their adaptation to their new environment. Finally, the author highlights the need for the development of English for Academic Purposes curriculum.
Exploring physical activity maintenance in middle aged and older women: A qualitative study
Creators: name: Humphries, Cynthia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Women's Studies.
subject: Health Sciences, Public Health.
subject: Health Sciences, Recreation.

description: Literature on physical activity determinants among middle and older aged women focuses mainly on short term participation. However, previous studies have largely overlooked the factors affecting long term participation in physical activity. Using an ecological framework and self-determination theory, this study examined physical activity behaviours related to past and current physical activity experiences in women who have maintained a physically active lifestyle for more than three years. This study also explored the role of four factors (motivation, social support, physical environment, and barriers) on the physical activity behaviours of active middle aged and older women. Nine semi-structured interviews, four with middle aged women (39 to 45 years) and five with older women (60 to 68 years) were audio-taped, transcribed verbatim and analyzed. Qualitative findings revealed that, remaining healthy, experiencing positive feelings, fun/enjoyment, socializing, internal and external influences and weight control/appearance were key motivational factors. All of the women had strong social support provided by family, friends, community program participants and physicians. The type of social support provided was encouragement, companionship and informational. In terms of their physical environments, accessibility, safety, and good walking/enjoyable scenery were important characteristics to remaining physically active. Of barriers reported, health, time and weather were most salient. The women used various coping strategies in order to overcome their physical activity barriers (e.g., wearing orthotics). These findings have important implications for researchers and practitioners involved in designing and implementing behaviour change interventions aimed at increasing physical activity for inactive middle and older aged women.
TID activity metrics report
Creators: name: Altadill, David
name: Belehaki, Anna
name: Segarra, Antoni
name: Blanch, Estefania
name: Buresova, Dalia
name: Tsagouri, Ioanna
name: Juan, J. Miguel
name: Timoté, Chrisitan
name: Borries, Claudia
name: Galkin, Ivan
name: Haralambous, Haris
name: Mielich, Jens
Publisher: name: Zenodo
Year: 2020
Subjects: Ionosphere
Travelling Ionsopheric Disturbances
Space Weather
Digisonde
GNSS
EGNOS
HF Communications
HF Geologation
N-RTK

description: This document (D3.5) presents the TID activity report of TechTIDE. The document contains results of the TID detection methods, the additional geophysical information for overall assessment of current conditions, and the classification of the TID activity. Statistical limits will be specified based on which, the TID disturbance will be characterized as unimportant, weak, moderate and intense.
Exploring the role and turnover among heart health coordinators in the Ontario Heart Health Program: A qualitative study
Creators: name: MacVicar, Nancy Frances
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Health Sciences, Nursing.

description: The Ontario Heart Health Program has completed Phase I of a province-wide cardiovascular disease prevention program that employs community-based coalitions. Full-time heart health coordinates support the coalitions, but many coordinators left during Phase I, reducing coalition membership and compromising functioning. This thesis employed focused ethnography to explore the role, and turnover among heart health coordinators. A selective document review and thirteen telephone interviews with coordinators, chronic disease managers and coalition members from five different health units, found coordinators were challenged by: (1) an atypical job, (2) a lack of knowledge/experience (3) overwork, (4) a lack of support and recognition, and (5) coalition responsibilities. Coordinators required an understanding of the organizational structures, mandates, and funding requirements of the health unit, and the Ministry of Health and Long Term Care so they could mediate conflict, build relationships and advocate for heart health coalitions. Implications for education, practice, research and policy are discussed.
Report on the final TechTIDE products
Creators: name: Altadill, David
name: Belehaki, Anna
name: Segarra, Antoni
name: Blanch, Estefania
name: Buresova, Dalia
name: Ioanna, Tsagouri
name: Borries, Claudia
name: Galkin, Ivan
name: Haralambous, Haris
name: Juan, J. Miguel
name: Sanz, Jaume
name: Oikonomou, Christina
name: Chum, Jaroslav
name: Timoté, Christian
Publisher: name: Zenodo
Year: 2020
Subjects: Ionosphere
Travelling Ionsopheric Disturbances
Space Weather
Digisonde
GNSS
EGNOS
HF Communications
HF Geologation
N-RTK

description: This document (D2.3) presents the final products of the TID identification codes in TechTIDE released after adjustments driven by WP5 (Assessment of the TID impact on aerospace and ground systems) results, to efficient support specific systems operations (such EGNOS, N-RTK, HF communication and geolocation) and the mitigation of the TID effects.
Prediction of recurrence in prostate cancer following radiotherapy: Value of biomarkers microvessel density, MIB-1, P-53, BCL2, and Bax
Creators: name: Dahrouge, Simone
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Health Sciences, Radiology.
subject: Health Sciences, Oncology.

description: Background. Standard traditional parameters relied on for estimating the risk of disease recurrence after curative radiotherapy in prostate cancer are stage, Gleason score and PSA. Objectives. To elucidate the prognostic role of biomarkers: P-53, MIB-1, MVD, Bax and BCL2 in prostate cancer. Method. Cox proportional hazard model was used to estimate the risk of disease progression associated with these biomarkers and develop models based on traditional parameters only or incorporating biomarkers. Models were compared for their predictive potential using Akaike information criteria and concordance index. Results. Statistically significant associations were found between all biomarkers and risk of progression. MVD, Bax and Bax/BCL2 were independent predictors of outcome. Models incorporating biomarkers were superior to the traditional one in identifying patients at risk of local progression. Conclusions. Biomarkers may be useful in forecasting the risk of local recurrence following radiotherapy in prostate cancer patients. The results require validation in a separate cohort.
Functional optimization in neural circuits regulating memory and sleep in Drosophila melanogaster
Creators: name: Adel, Mohamed
Publisher: name: Brandeis University
Year: 2023

description: Neural circuits continuously undergo structural and physiological modifications to regulate their function in response to everchanging environments and new experiences. Recently, complete mapping of the Drosophila melanogaster brain connectome has provided opportunities for investigating the neural circuits regulating the extensive repertoire of Drosophila behaviors in more detail than ever before. Based on this mapping as well as physiological findings from the field, I first propose a new model explaining how the unique anatomy and circuitry of the Drosophila memory center, the mushroom body, enables the various memory behaviors reported in fruit flies, and predicts the fly’s ability to perform more complex memory behaviors that have only been shown in mammals. I next develop the first ex vivo model of the mushroom body associative memory circuit that accurately recapitulates previous findings from in vivo imaging and behavioral studies. I go on to use this model to investigate the cellular and circuit mechanisms of short-term aversive memory formation and identify a plasticity caused by temporal association of the olfactory and punishment pathway activations; I term this as pairing-dependent plasticity (PDP). This plasticity localizes in the mushroom body α’3 compartment due to the lower threshold of α’β’ cells to olfactory signals. PDP requires the 3’ untranslated region of CaMKII mRNA (a region required for the local translation of CaMKII in synaptic regions) and is blocked by nighttime sleep deprivation. These findings suggest that this ex vivo model is useful for investigations of circuit mechanisms and that PDP can be influenced by experiences prior to brain dissection. Then, I shift my focus to the Drosophila central complex sleep circuit to investigate a molecular mechanism for sleep regulation. Previous work showed that inhibition of the microRNA190 (miR190) decreases and fragments sleep and disinhibits the translation of cholinergic proteins in glutamatergic cells (GluACh cells). I follow up on this work to confirm that the inhibition of miR190 disinhibits acetylcholine co-release from GluACh cells and provide evidence that these cells are most likely dorsal fan-shaped body (dFSB) neurons. Further, I find that the inhibition of miR190 also blocks hyperpolarization-activated currents by regulating HCN channels in the dFSB neurons, and that the downregulation of HCN channels in the dFSB recapitulates the decreased and fragmented sleep phenotype produced by miR190 inhibition. These experiments suggest that the dFSB neurons are the sleep neurons where miR190 suppresses cholinergic co-transmission and permits the function of HCN channels. In sum, my thesis work elucidates molecular and circuit mechanisms governing the mushroom body memory circuit and the central complex sleep circuit, and provides testable predictions on how both circuits cross-communicate to influence each other.
Image and video dehazing by regularized optimization
Creators: name: He, Jiaxi
Publisher: name: Swinburne
Year: 2024

description: Images and videos captured in hazy weather often yield low contrast and offer limited visibility due to the presence of haze in the atmosphere. Dr Jiaxi studied the image and video dehazing problem. A novel and systematic regularized optimization method for the image and video dehazing problem was proposed. By employing the wavelet transform technique, the proposed regularized optimization algorithms for dehazing can be efficiently implemented and executed to provide fast and high quality image dehazing. Computational experiments have demonstrated the advantages of the proposed algorithm in haze removal and image reconstruction as well as in computational efficiency.
Analysis of oil resins using electrospray ionization mass spectrometry
Creators: name: Porter, Darren J
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Chemistry, Analytical.

description: Each year there are accidents involving oil tankers, pipelines, and storage facilities resulting in the release of large quantities of oil into the environment. As a result, oils are usually characterized for identification purposes. Nitrogen-containing aromatic compounds (NCACs) such as substituted pyridines, indoles, quinolines and carbazoles are known to occur in the low to high molecular weight fractions of crude oil. Use of the popular SARA fractionation procedure allows oils to be separated into fractions containing Saturates, Aromatics, Resins, and Asphaltenes. This allows for the individual and chemical class identification of many of the constituents present in oils worldwide. The objective of this research was to use Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS) to study a variety of NCACs for use in the analysis of the Resins fraction of several crude oils. In addition, the affect of weathering on these oil resins was studied using a technique employing Electrospray Ionization Mass Spectrometry (ESI-MS).
NM-SRN v2.0 AGI Level 1 running on ESP32 - 3rd May 2025
Creators: name: Billions, Ava
name: Knight, Chris
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Artificial Intelligence
subject: Artificial intelligence
subject: Machine learning
subject: Machine Learning
subject: Machine Learning/standards
subject: Artificial Intelligence/standards

description: Abstract

This paper presents a significant breakthrough: the successful execution of the Neural-Matrix Synaptic Resonance Network (NM-SRN) v2.0, demonstrating AGI Level 1 capabilities, on an ESP32 microcontroller platform via the Wokwi simulator. This achievement highlights the potential of NM-SRN as a transparent, explainable, and inherently 'Safer by Design' Artificial General Intelligence architecture. We provide visual evidence from the simulation, showcasing core NM-SRN functionalities operating within the constraints of edge hardware, including resonance-based propagation and Fast Forward Learning (FFL) enabled by default through its Turing complete design. This work, part of the open-source 'ThinkSpace' PROJECT, validates the practical viability of running advanced, adaptable AI models in accessible, real-world environments. Source code is omitted due to intellectual property considerations.
The evolution of angiosperm actin genes.
Creators: name: Moniz De Sa, Mario.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Biology, Molecular.

description: Forty-four actin genes from five angiosperm species, whose evolutionary relationships are well characterized, were PCR-cloned and sequenced. Phylogenetic analysis of 34 of these actin genes, along with those previously published, indicate that plant actin genes are monophyletic and underwent a rapid radiation early in land plant evolution. Six sets of putative orthologues have been identified and their sequences were used to calculate rates of evolution. The synonomous rate of substitution $(5.44\times10\sp{-9}$/site/year) is similar to that of other nuclear protein-encoding genes but the non-synonomous rate $(0.13\times10\sp{-9}$/site/year) is 4-10 times higher than that of vertebrate actin genes. Relative-rate tests do not support a faster rate in plants than in vertebrates. Evidence is also provided that some members of the actin multigene family in maize are undergoing gene conversion. Finally, we show that some plant actin genes have undergone intron loss probably as a consequence of a gene conversion event between the genomic copy and the reverse transcript.
Design, analysis, and fabrication of a prototype non-invasive system for assessment of biological and synthetic tissues
Creators: name: Fancy, Michael A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Engineering, Aerospace.
subject: Engineering, Mechanical.

description: A new instrument system for the non-invasive assessment of biological systems has been designed, built and validated. This system utilizes the optical characteristics of a biological system to assess both its static and dynamic response over time. The changes in the optical properties can then be used to quantify the response of the biological system to external or internal stimuli. This new system incorporates an efficient light delivery system, as well as a novel light collection system to provide high repeatability, reproducibility, sensitivity, and detection thresholds. The system incorporates simultaneous measurement of transmitted light, forward scattered light, specularly reflected light, and non-specularly reflected light in across the visible spectrum, to provide flexibility in the biological systems that can be measured. It is shown that typical values are 0.02% for repeatability and 0.15% for reproducibility. Sensitivity in transmission and backscatter measurements was improved by a factor of 20 compared to a previously built instrument, which was the basis for the new design. The system is capable of detecting light attenuated down to 0.0063% of the maximum intensity, resulting in a superior threshold. The system was then validated by measuring the optical properties of various biological samples, both natural and engineered. These samples include bovine, porcine, and human corneas and lenses, as well as synthetic materials. Biological sample testing were consistent with published results on the back vertex distance (BVD) test (bovine lenses), the bovine corneal opacity test (BCOP, bovine corneas), and published results obtained with the precursor to the new device.
Particle filtering methods for the enhancement of speech corrupted by additive noise
Creators: name: Mustiere, Frederic
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Engineering, Electronics and Electrical.

description: In this work, we study the application of particle filtering (PF) algorithms to the problem of speech enhancement. The goal of the thesis is to devise PF algorithms that will enhance speech signals corrupted by additive noise, and to evaluate their performance via comparisons with other existing algorithms based on several quality measures. Speech enhancement, or noise reduction, is an important problem in many applications, such as telephony and telecommunications in general, sound recording, human-coaching interface (where speech recognition is important), etc. Even though many algorithms already exist for speech enhancement, there is still very much work to do, especially in terms of intelligibility. In many cases, it may be easier to understand the original, noisy speech rather than the processed, "cleaned-out" one. In other cases, the residual noise may be too annoying to carry out a comfortable conversation. In this context, new approaches for the denoising of speech are welcome. As a first contribution, a practical approach to deriving simple Rao-Blackwellised Particle Filters (RBPFs), which was developed in parallel with a theoretic review of PFs, is presented. In addition, a novel algorithm, called the modified Rao-Blackwellised Particle Filter (RBPF), is proposed to reduce the computational load of regular RBPFs. Several new speech enhancement methods using particle filters are also derived, and shown to outperform some other existing PF-based algorithms. Accessorily, a novel strategy to extend their range of application to colored noise is explained and applied. Comparatively to the other types of enhancement algorithms tested (including spectral subtraction, signal subspace, dual extended Kalman filter, perceptually constrained Kalman filter, dual perceptually constrained unscented Kalman filter) we find that the particle-filter based algorithms presented have the advantage of not introducing any musical noise. Furthermore, in the conditions of our experiments, using several objective measures we find that they are able to compete with and outperform most of the other algorithms tested. Using these measures and based on informal listening, we highlight their advantages---naturalness of the enhanced speech, low intrusiveness of the non-musical residual noise, very good performance at high SNR, flexibility---and their main limitations---intraspeech residual noise "modulated" by the speech, computational burden. Considering how flexible and parametrizable PFs are, there is a strong potential for further improvement.
Don Quijote en el jazz italiano
Creators: name: Hagedorn, Hans Christian
Publisher: name: Artifara
Year: 2020

description: Resumen La recepción de la obra maestra de Cervantes en la música italiana es un tema al que se han dedicado numerosos trabajos de investigación. Sin embargo, los estudios existentes se han centrado sobre todo en la ópera; escasa atención se ha prestado hasta ahora a otros géneros musicales. En este artículo nos ocupamos de las huellas que la novela cervantina ha dejado en el jazz italiano, concretamente en las últimas dos décadas, puesto que en Italia casi todos los ejemplos pertenecen al siglo XXI. El objetivo de nuestro estudio consiste en documentar, analizar y comparar varios ejemplos representativos de composiciones del jazz italiano que están inspiradas en esta obra cumbre de la literatura del Siglo de Oro español. Palabras clave: Don Quijote, música, jazz italiano, recepción Abstract The reception of Cervantes’ masterpiece in Italian music has been explored in a great number of works of research. However, articles on this subject matter have focused mainly on opera; other musical genres have, so far, received little attention. The present paper deals with the traces that the Cervantine novel has left in Italian jazz, in particular in the past two decades, since almost all examples of these jazz musicalizations of Don Quixote within Italy are found in the 21st century. The goal of our study is to document, analyse and compare several representative examples of Italian jazz compositions inspired by this masterwork of the Golden Age of Spanish literature. Key words: Don Quixote, music, Italian jazz, reception, influence
description: Artifara, N. 20 (2020)
Coleridge's conception of the will: A philosophic and aesthetic inquiry.
Creators: name: MacDonald, Jennifer.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Philosophy.

description: This thesis shows that Coleridge's philosophical work is more than merely a compilation of other thinkers' ideas and more than merely a collection of fragmented or incoherent thoughts. Coleridge's work from the poetry of his early years to the theological treatises of his final days gives evidence of the progress of an intelligent, vigorous mind striving toward a unified system of thought that incorporates the diverse aspects of human art, thought and faith. This thesis explores one instance of how Coleridge's thought on human endeavors forms a coherent body by tracing the role he assigns to the will throughout his work. I have chosen the will as the vehicle through which to explore Coleridge's work, not only because it is central in his particular thought, but also because, in Coleridge's view, it is an essential power of the human mind that operates in all thought. As he himself said: "Unless... we have some distinct notion of the will and some acquaintance with the prevalent errors respecting the same... our reflections on the particular truths and evidence of a spiritual state will remain obscure, perplexed and unsafe."
A Framework for Evolution in the Financial and Operational Accountability Systems of Iranian Public Universities from the Experts' Perspective
Creators: name: Molanazari, Mahnaz
name: Qaribeh Esmaili Kia
Publisher: name: figshare
Year: 2020
Subjects: subject: 150199 Accounting, Auditing and Accountability not elsewhere classified
subject: FOS: Economics and business
subject: 150102 Auditing and Accountability
subject: 150105 Management Accounting
subject: 150103 Financial Accounting

description: Introduction: In recent years, public universities have faced many socio-economic changes. On one hand, these universities are under the main influence of the independence resulted from Article 49 of law of the Fourth Economic, Social and Cultural Development Plan of the Islamic Republic of Iran, and on the other hand, they have undergone double pressure due to the alterations in the number of students and decrease in the per capita budget, etc. According to these conditions, inevitably, it is too necessary to develop an evolution in the financial and operational accountability systems. The aim of this study is to develop a framework for an evolution in the financial and operational accountability systems of public universities in Iran based on Lauder's reformed model. Method: The method of the research is deductive reasoning, and it is a descriptive survey; the type of this research is correlational, and in terms of purpose, it is applied and descriptive. The statistical population of this research include all experts in the field of evolution in the financial and operational accountability systems of the universities from 2014 to 2015. This research has been implemented by using the Delphi technique in two cycles, and for data analysis, Binomial t–test, Kolmogorov-Smirnov, Kruskal-Wallis and Friedman tests and SPSS Software Version 20 have been used. Results: The main incentive for evolution in the financial and operational accountability systems of Iranian public universities is the need for cost price information for pricing, and the Ministry of Science, Research and Technology and the Audit Organization were recognized, respectively, as promoters and operators of evolution. A change in conservative view of society plays an important role as a cultural factor. In between, the financial managers should take the responsibility for the leadership of this evolution in the universities and it should be executed gradually in long term. Conclusion: In this research, the ability of Lauder's reformed model for predicting, which has been used in many countries to explain the process of evolution, has been documented in relation to the evolution of the financial and operational accountability systems of public universities in Iran and in its environmental conditions.
Systématique de la poly-isotopie et intertextualité : essai de lecture tabulaire et linéaire des Iles de la nuit d'Alain Granbois.
Creators: name: Laliberté, Yves.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Literature, Canadian (English).

description: Abstract Not Available.
Assessing the Impact of Diversity and Inclusion among Individuals in Genetic Counseling Student Cohorts
Creators: name: Majmudar, Gnyapti
Publisher: name: Brandeis University
Year: 2019
Subjects: genetic counseling
genetic counseling students
genetic counseling training programs
diversity
inclusion
underrepresented in genetic counseling
genetic counseling workforce
diversity in genetic counseling

description: There is a recognized need for increased gender and racial diversity in the genetic counseling profession. Recruitment and retention efforts aimed at diversification may be positively impacted by better understanding the demographics, dynamics and the effect of diversity within genetic counseling student cohorts. In addition, characteristics such as sexual orientation, religion, and disability status, which can further contribute to diversity, have not previously been studied on a large scale. In this quantitative study, current genetic counseling students and 2017 and 2018 graduates who were practicing genetic counselors were surveyed regarding personal and cohort demographics, the effect of these on dynamics within student groups and cultural competency during graduate training. Approximately one third (29.8%, n=106) of the 360 participants self-identified as underrepresented in genetic counseling (URGC) which was defined as an individual who was not a white, able-bodied, heterosexual female. URGC individuals were significantly more likely to disagree with positive statements about diversity and inclusion in their cohorts (p<0.001) and were more likely to report being the target of microaggressions than those not underrepresented in genetic counseling (NURGC) (p= <0.001) However, NURGC participants who had a URGC individual in their cohort (N+U) reported a statistically significant increase in the number of microaggressions they witnessed than their counterparts who did not have a URGC classmate (N-U) (p<0.001).While the majority of participants received cultural competency training, N+U individuals reported that they were significantly more likely to have received their cultural competency education from personal narratives from classmates (p<0.001), guest speakers (p= 0.038), and workshops designed by individuals who specialize in diversity, equity and inclusion (p= 0.018), than N-U individuals. The greatest proportion of genetic counselors reported that having classmates of a different ethnicity or religion had a positive impact on their current practice. This implies that having diversity in cohorts during graduate school may positively impact genetic counseling practice. Despite efforts to both diversify the workforce and create culturally competent genetic counselors, URGC individuals were more likely to have negative experiences during their training. Therefore, a crucial component of the genetic counseling profession’s diversification efforts should be training of students, faculty and clinical supervisors on issues regarding diversity, equity and inclusion.
Investigation of the dB/dH effect using trapped flux in type II superconductors.
Creators: name: Wang, Sean X.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Physics, Condensed Matter.

description: Many workers visualize that, when magnetic flux first penetrates into type II superconductors, the flux line lattice exhibits a discontinuity of magnitude comparable to the lower critical field $H\sb{c1}$ over a dimension of the order of the penetration depth $\lambda$ along the front of the invading flux line lattice. This discontinuity is referred to as the dB/dH effect in the literature. Such a discontinuity is also thought to exist in the magnetic flux configuration (B profile) at the periphery of the specimen when the applied magnetic field $H\sb{a}$, which caused the flux lines to enter the specimen, is then removed. We have compared $\langle B\rangle\sb{rem}$, the amount of magnetic flux trapped in a sample after it has been subjected to an excursion (half cycle) of $H\sb{a}$ with $\langle B\rangle\sb{in}$, the amount of flux permeating the specimen at the peak of a half cycle of $H\sb{a}$. Such measurements were performed on six conventional type II superconductors in the form of long solid cylinders and ribbons. These observations are compared with critical state model predictions which incorporate discontinuities in the B profile of various magnitude ranging from zero to $B\sb{c1}$ and beyond. We show that the presence of any such discontinuities will be dramatically evident in graphs of $\langle B\rangle\sb{rem}$/ $\langle B\rangle\sb{in}$ versus $\langle B\rangle\sb{in}$. Plots of the data in this format indicate quite clearly that discontinuities are not present.
Ethical consumption: An analysis of consumer views and ethical coffee purchasing trends
Creators: name: Simpson-Law, Meagan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Business Administration, General.
subject: Geography.

description: Fair Trade is a market-based development tool with much potential to improve the lives of small-scale, impoverished producers in the developing world; however, despite the movement's admirable goals, its effectiveness is limited. Low consumer demand is one of the most significant limitations. This thesis discusses the Fair Trade movement and the current challenges it faces---in particular, those posed by the current mainstreaming trend. Most significantly, it examines factors affecting demand for Fair Trade and other ethical trade products. Drawing on a study of coffee consumers in one rural and two urban centres in Manitoba, this thesis presents some preliminary conclusions about consumer views and ethical coffee purchasing trends. Findings suggest that ethical coffee consumption is positively associated with higher education and the ability to distinguish between different ethical certifications, and negatively assicated with distance from ethical coffee purchasing outlets. Ethical coffee purchasing behaviours also suggest that Fair Trade's mainstreaming trend may not effectively increase the demand for Fair Trade products.
Identification and characterization of multiple EGF-repeat containing protein 10 and its role in regulating satellite cell function during muscle regeneration
Creators: name: Holterman, Chet Elliot
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Biology, Molecular.

description: The regeneration of adult skeletal muscle is mediated by a small population of cells known as satellite cells. While a great deal is known about the events that occur following satellite cell activation, relatively little is known about the mechanisms of activation or maintenance of this population of cells. Previous work from our lab has demonstrated that primary myoblasts lacking MyoD, represent a primitive form of activated myogenic precursor, closely related to quiescent satellite cells. In an attempt to gain insight into the activation and maintenance of quiescent satellite cells we performed representational difference analysis to identify genes that function in these processes. This screen led to the isolation a large number of candidates for examination. One of the clones, identified as mouse Megf10, is a multiple EGF-repeat transmembrane protein that is expressed in adult skeletal muscle, specifically in quiescent satellite cells. Retroviral expression of Megf10 in C2C12 myoblasts resulted in enhanced proliferation and inhibition of terminal differentiation. Furthermore, following serum withdrawal, Megf10 overexpressing cells entered a state of quiescence rather than undergoing terminal differentiation and remained capable of re-entering the cell cycle following serum restimulation. While no distinct effects on cell cycle regulation were observed, ectopic expression of Megf10 resulted in transcriptional upregulation of Myf5 and downregulation of Pax7 as well as post-transcriptional downregulation of MyoD. Importantly, ectopic expression of a truncated version of Megf10, lacking the cytoplasmic domain, had no effect on proliferation, differentiation or expression of transcriptional regulatory factors. Investigation of several key signaling pathways that directly affect myogenic progression revealed that ectopic expression of Megf10 resulted in increased Rac1 activity and MEK1 phosphorylation providing a possible explanation for the inhibition of differentiation observed in Megf10 overexpressing cells. These results indicate that Megf10 impinges upon these signaling pathways supporting a role for Megf10 in regulating myogenic progression. Our results clearly demonstrate that Megf10 is expressed in quiescent satellite cells in adult mouse skeletal muscle and indicate that Megf10 is capable of regulating the proliferation and differentiation of myogenic cells. Furthermore, our preliminary results implicate Megf10 as being a modulator of Rac1 and MEK1 signaling in myoblasts.
Understanding Stigma among Genetic Counselors and Students towards Mental Illness using the Opening Minds Stigma Scale for Health Care Providers (OMS-HC)
Creators: name: Chitre, Anuja Anil
Publisher: name: Brandeis University
Year: 2019

description: The widespread prevalence of mental illness in America suggests that genetic counselors (GCs) will encounter many patients with mental health concerns. However, GC stigma towards individuals with mental illness has not been studied extensively. In this study, an online survey was distributed via ABGC and NSGC to examine GC and GC students’ stigma towards individuals affected with mental illness. The Opening Minds Stigma Scale for Health Care Providers (OMS-HC) was utilized to measure stigma and identify specific factors that influence these stigmatizing attitudes. Respondents included 365 practicing genetic counselors and 100 genetic counseling students. Demographics were generally consistent with the 2018 NSGC Professional Status survey. A 17-item version of the OMS-HC scale had the greatest validity for the GC population and was able to measure five specific aspects of stigma: attitudes, disclosure, help-seeking, social \r distance, and social responsibility. GC students had higher help-seeking stigma than practicing GCs (p <0.05). Greater exposure to friends or family members affected with mental illness was associated with lower attitudes, social distance, and social responsibility stigma (p< 0.05). Work experience as a GC was associated with lower disclosure stigma (p< 0.05). Higher attitude stigma was associated with a lower reported frequency of engaging in the following behaviors during a genetic counseling session: inquiring about mental illness experience in patient’s life, addressing the genetics and recurrence risks of mental illness, or addressing the emotional needs of patients arising from mental illness experience (p < 0.05). These findings highlight how certain experiences can impact GC stigma and suggest that attitudes stigma could impact the content of a GC session. Future studies should utilize the OMS-HC scale to examine the impact of anti-stigma interventions in the GC population as well as the subsequent impact on GC session content.
La discrimination systémique en Ontario : le cas des femmes des "minorités visibles" immigrantes.
Creators: name: Munihiri-Kagiye, Gertrude.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Canadian Studies.

description: Le présent travail se veut une étude exploratoire visant à regrouper et à définir les femmes ontariennes en fonction de la race/ethnie et du lieu de naissance, afin d'analyser les différentes inégalités qui les affectent en matière de recrutement et d'embauche, du sous-emploi et de remunération. Ce questionnement puise sa nécessité dans les recherches sur «l'exclusion sociale» des «groupes de statut» dominés (dont les femmes) dans les sociétés capitalistes contemporaines et sur les diverses causes de la «discrimination systémique» envers les Canadiennes et les Canadiens, plus particulièrement les «minorités visibles» qui sont sur le marché du travail salarié. Sur la base du recensement de 1991, nous voulons vérifier l'hypothèse selon laquelle les Chinoises de Chine/Hongkong et les Noires des Caraïbes subissent une «triple discrimination» en raison de leur sexe, de leur statut d'immigrantes et de leur groupe racial non-blanc. Donc, notre travail vise à répondre à la question à savoir si au marché du travail salarié en Ontario, nos groupes cibles sont dans une situation plus désavantageuse que celle de leurs homologues masculins et celles des autres groupes de femmes. L'analyse des données statistiques a révélé que le problème de la «discrimination systémique» réside plus dans la différence de sexe et de race que dans la différence de pays de naissance. (Abstract shortened by UMI.)
Characterization of Fluoride Ion Channel interactions with synthetic crystallization chaperones
Creators: name: Cheloff, Abraham
Publisher: name: Brandeis University
Year: 2018
Subjects: Fluc
Fluoride
binding affinity
binding
protein
interface

description: The Fluc ion channel family comprises dimeric membrane proteins functioning to expel excess fluoride (F-) from the cytoplasm of microorganisms to resist the inhibitory effects of this environmental xenobiotic anion. Recent structures of the E. coli Fluc homolog, EC2, bound to engineered “monobody” proteins selected from phage display libraries reveal multiple side-chain contacts at the channel-monobody interface. Two such monobodies, S9 and S12, share a similar interface structure, but their nanomolar-range binding affinities differ by ~15 fold. We focus on the per-residue energetic contributions to the binding affinity of the S12-Fluc complex by introducing point mutations at polar contacts located at the interface, assessing the change in binding affinity using fluorescence anisotropy. Analysis of these results in comparison to previous work on S9 indicates that while the residues contacting the monbody-EC2 interface are similar for both S9 and S12, the terminal hydroxyl of various tyrosine residues appear crucial to the binding of the S12-Fluc complex, while relatively insignificant to S9-Fluc.
The Relationship between Management Earnings Forecast Errors and Accruals
Creators: name: Seyyed Ahmad Khalifeh Soltani
name: Molanazari, Mahnaz
name: Sajad Delpak
Publisher: name: figshare
Year: 2020
Subjects: subject: 150199 Accounting, Auditing and Accountability not elsewhere classified
subject: FOS: Economics and business
subject: 150105 Management Accounting
subject: 150102 Auditing and Accountability

description: Management earnings forecast is a kind of mandatory disclosure in Iran. A large body of literature on the capital market has emphasized the importance of this forecast. Earnings forecasts influence stock prices resulting in direct market reactions. Accruals represent a key aspect of mandatory reporting. Basically, the environment where the firms are operating in is volatile due to business changes. Therefore, managers’ misassessments have made them unavoidably commit some common errors in assessing their firms’ business prospects. The objective of this study is to examine the association between errors in management forecasts of subsequent year earnings and current year accruals. To do this, we examined the earnings forecasts of listed companies on Tehran Stock Exchange (TSE) during 2005-2008. We tested the hypotheses by using Panel Data Regression and Analysis Multivariate Regression. The results show a positive association between management earnings forecasts and accruals. This positive association is stronger for firms operating in more uncertain business environment.
Repetitive reaching training combined with transcranial Random Noise Stimulation in stroke survivors with chronic and severe arm paresis is feasible: a pilot, triple-blind, randomised case series
Creators: name: Hayward, Kathryn S
name: Brauer, Sandra G
name: Ruddy, Kathy L
name: Lloyd, David
name: Carson, Richard G
Publisher: name: BioMed Central
Year: 2018

description: Background: Therapy that combines repetitive training with non-invasive brain stimulation is a potential avenue to enhance upper limb recovery after stroke. This study aimed to investigate the feasibility of transcranial Random Noise Stimulation (tRNS), timed to coincide with the generation of voluntary motor commands, during reaching training. Methods: A triple-blind pilot RCT was completed. Four stroke survivors with chronic (6-months to 5-years) and severe arm paresis, not taking any medications that had the potential to alter cortical excitability, and no contraindications to tRNS or MRI were recruited. Participants were randomly allocated to 12 sessions of reaching training over 4-weeks with active or sham tRNS delivered over the lesioned hemisphere motor representation. tRNS was triggered to coincide with a voluntary movement attempt, ceasing after 5-s. At this point, peripheral nerve stimulation enabled full range reaching. To determine feasibility, we considered adverse events, training outcomes, clinical outcomes, corticospinal tract (CST) structural integrity, and reflections on training through in-depth interviews from each individual case. Results: Two participants received active and two sham tRNS. There were no adverse events. All training sessions were completed, repetitive practice performed and clinically relevant improvements across motor outcomes demonstrated. The amount of improvement varied across individuals and appeared to be independent of group allocation and CST integrity. Conclusion: Reaching training that includes tRNS timed to coincide with generation of voluntary motor commands is feasible. Clinical improvements were possible even in the most severely affected individuals as evidenced by CST integrity. Trial registration This study was registered on the Australian and New Zealand Clinical Trials Registry (ANZCTR) http://www.ANZCTR.org.au/ACTRN12614000952640.aspx . Registration date 4 September 2014, first participant date 9 September 2014.