cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Towards autonomous service level agreement negotiation for adaptive service composition
Creators: name: Yan, Jun
name: Zhang, Jianying
name: Lin, Jian
name: Baruwal Chhetri, Mohan
name: Goh, Suk K.
name: Kowalczyk, Ryszard
Publisher: name: Swinburne
Year: 2024

description: This paper reports innovative research aiming at supporting autonomous establishment and maintenance of service level agreements in order to guarantee end-to-end quality of service requirements for service composition provision. In this research, a set of interrelated service level agreements is established and maintained for a service composition, through autonomous agent negotiation. To enable this, an innovative framework is proposed in which agents on behalf of the service requestor and the service providers can negotiate service level agreements in a coordinated way. This framework also enables adaptive service level agreement re-negotiation in the dynamic and ever-changing service environmentAbstract not available.
Specimens from Schärer et al. 2011, "Mating behavior and the evolution of sperm design"
Creators: name: Schärer, Lukas
Publisher: name: Zenodo
Year: 2019
Subjects: Macrostomum
Free-living flatworm

description: The deposited folders contain image and video material of free-living flatworm specimens that were documented in vivo. These data support the following publication: Schärer, L., D. T. J. Littlewood, A. Waeschenbach, W. Yoshida, and D. B. Vizoso. 2011. Mating behaviour and the evolution of sperm design. Proc. Natl. Acad. Sci. USA 108:1490-1495. For more information about these specimens see also http://macrostomorpha.myspecies.info.
description: {"references": ["Sch\u00e4rer, L., D. T. J. Littlewood, A. Waeschenbach, W. Yoshida, and D. B. Vizoso. 2011. Mating behaviour and the evolution of sperm design. Proc. Natl. Acad. Sci. USA 108:1490-1495."]}
Identification and Validation of novel genes implicated in Neurosensory and Neurological Diseases
Creators: name: Kröll-Hermi, Ariane
Publisher: name: Karlsruhe
Year: 2020

description: Worldwide, there are more than 7,000 rare diseases for which 80 % are of genetic origin and for which the gene or genes are not yet all known. Although the interest in rare diseases has increased in recent years, there is a lack of therapeutic strategies for most of them. During my thesis, I focused on the identification and validation of new genes associated with neurosensory and neurodevelopmental diseases. The strategy I used during my thesis to identify new disease-causing genes is based primarily on the analysis of high-throughput sequencing data from patients, the confirmation of variants by Sanger sequencing, and the performance of functional experiments using patient cells and the zebrafish model to proof the pathogenicity of the novel gene mutations. Overall, I contributed to the identification of three novel disease genes associated with neurodevelopmental and neurosensory diseases. The results obtained in this thesis improve the understanding of the pathophysiology of these diseases and may help to find new therapeutic targets.
title: Characterization of the soft X-ray spectrometer PEAXIS at BESSY II
Creators: name: Schulz, Christian
name: Lieutenant, Klaus
name: Xiao, Jie
name: Hofmann, Tommy
name: Wong, Deniz
name: Habicht, Klaus
Publisher: name: Universität Potsdam
Year: 2024
Subjects: subject: 530 Physik

description: The performance of the recently commissioned spectrometer PEAXIS for resonant inelastic soft X-ray scattering (RIXS) and X-ray photoelectron spectroscopy and its hosting beamline U41-PEAXIS at the BESSY II synchrotron are characterized. The beamline provides linearly polarized light from 180 eV to 1600 eV allowing for RIXS measurements in the range 200-1200 eV. The monochromator optics can be operated in different configurations to provide either high flux with up to 10(12) photons s(-1) within the focal spot at the sample or high energy resolution with a full width at half maximum of <40 meV at an incident photon energy of similar to 400 eV. The measured total energy resolution of the RIXS spectrometer is in very good agreement with theoretically predicted values obtained by ray-tracing simulations. PEAXIS features a 5 m-long RIXS spectrometer arm that can be continuously rotated about the sample position by 106 degrees within the horizontal photon scattering plane, thus enabling the study of momentum-transfer-dependent excitations. Selected scientific examples are presented to demonstrate the instrument capabilities, including measurements of excitations in single-crystalline NiO and in liquid acetone employing a fluid cell sample manipulator. Planned upgrades of the beamline and the RIXS spectrometer to further increase the energy resolution to similar to 100 meV at 1000 eV incident photon energy are discussed.
description: Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe; 1355
For an Hour or So: A Corpus Analysis of Diminutive Temporal Adverbials with Delimitative Nouns in Russian
Creators: name: Menzenski, Matthew
Publisher: name: figshare
Year: 2015
Subjects: subject: Linguistics
subject: FOS: Languages and literature
subject: Language

description: Prior research has argued that the morphology of Russian verbal aspect parallels nominal morphology in many ways. This thesis uses data from the Russian National Corpus to extend that analysis, arguing that the functions of the delimitative prefix po- and the functions of nominal diminutive markers overlap significantly.
Variation in subnational electoral authoritarianism: evidence from the Russian Federation
Creators: name: Saikkonen, Inga A.-L.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Despite the burgeoning comparative literature on electoral authoritarian regimes, fewer studies have accounted for the emergence of hegemonic and competitive authoritarian regimes at the subnational level. This article examines the variation in subnational electoral authoritarianism with data from the Russian Federation. First, the article shows that by using a comparative regime classification most Russian subnational cases can be classified as electoral authoritarian between 1991 and 2005. Yet, there are considerable differences in competitiveness between the electoral authoritarian regimes. The article accounts for this variation by drawing on both comparative electoral authoritarianism literature as well as more context-specific explanations. Statistical analysis on 192 subnational electoral authoritarian cases shows that the determinants of Russian subnational authoritarian stability are rather similar to those found in cross-national studies. Subnational (non)competitiveness in Russia appears to be related to the structure of the regional economy and natural resource rents, and to a lesser degree to the specific Russian federal context. Authoritarian “know how” also plays a role in authoritarian regime building. The findings of the article contribute to the literature on electoral authoritarianism, subnational democratization and Russian subnational politics.
Variation in subnational electoral authoritarianism: evidence from the Russian Federation
Creators: name: Saikkonen, Inga A.-L.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Despite the burgeoning comparative literature on electoral authoritarian regimes, fewer studies have accounted for the emergence of hegemonic and competitive authoritarian regimes at the subnational level. This article examines the variation in subnational electoral authoritarianism with data from the Russian Federation. First, the article shows that by using a comparative regime classification most Russian subnational cases can be classified as electoral authoritarian between 1991 and 2005. Yet, there are considerable differences in competitiveness between the electoral authoritarian regimes. The article accounts for this variation by drawing on both comparative electoral authoritarianism literature as well as more context-specific explanations. Statistical analysis on 192 subnational electoral authoritarian cases shows that the determinants of Russian subnational authoritarian stability are rather similar to those found in cross-national studies. Subnational (non)competitiveness in Russia appears to be related to the structure of the regional economy and natural resource rents, and to a lesser degree to the specific Russian federal context. Authoritarian “know how” also plays a role in authoritarian regime building. The findings of the article contribute to the literature on electoral authoritarianism, subnational democratization and Russian subnational politics.
Wertepluralismus als eine (auch innerislamische) Herausforderung an das Zusammenleben der Muslime in einer religiös pluralen Gesellschaft
Creators: name: Khorchide, Mouhanad
Publisher: name: Münchener Theologische Zeitschrift
Year: 2020

description: Münchener Theologische Zeitschrift, Bd. 69 Nr. 2 (2018)
Specimens from Janssen et al. 2015, "The first multi-gene phylogeny of the Macrostomorpha sheds light on the evolution of sexual and asexual reproduction in basal Platyhelminthes"
Creators: name: Schärer, Lukas
Publisher: name: Zenodo
Year: 2019
Subjects: Macrostomum
Free-living flatworm

description: The deposited folders contain image and video material of free-living flatworm specimens that were documented in vivo. These data support the following publication: Janssen, T., D. B. Vizoso, G. Schulte, D. T. J. Littlewood, A. Waeschenbach, and L. Schärer. 2015. The first multi-gene phylogeny of the Macrostomorpha sheds light on the evolution of sexual and asexual reproduction in basal Platyhelminthes. Mol. Phylogenet. Evol. 92:82-107. For more information about these specimens see also http://macrostomorpha.myspecies.info.
description: {"references": ["Janssen, T., D. B. Vizoso, G. Schulte, D. T. J. Littlewood, A. Waeschenbach, and L. Sch\u00e4rer. 2015. The first multi-gene phylogeny of the Macrostomorpha sheds light on the evolution of sexual and asexual reproduction in basal Platyhelminthes. Mol. Phylogenet. Evol. 92:82-107."]}
Multinuclear magnetic resonance study of equilibria between aluminum(III) and sulfur-containing amino acids in aqueous solutions
Creators: name: Thaís Tenório
name: Tenório, André
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry
subject: Biophysics

description: Aluminum(III) is generally found in small amounts in living organisms where it interacts with several biomolecules. Low mass biomolecules can form complexes associated with absorption and distribution processes of this toxic ion. However, investigating aluminum(III) complexes in solution poses singular difficulties, because it is highly hydrolyzable. Amino acids constitute possible ligands for aluminum(III). Methionine, cysteine and homocysteine are found in healthy human body. Penicillamine is a drug used in several circumstances, such as in treating metal poisoning. These four biomolecules share similar donor atoms involved in complexation reactions: a carboxylate oxygen, an amine nitrogen and sulfur. In this study, four binary complexes formed by aluminum(III) and amino acids in solution at a metal-to-ligand ratio of 1:1 were analyzed through potentiometry and multinuclear magnetic resonance (13C and 27Al). Potentiometry data consistently demonstrated complexion formation. Distributions of species revealed the coexistence of several species in ample pH ranges and pointed out the preferable value to perform the NMR analyses. 13C NMR data were used to confirm complexion formation, while 27Al NMR data indicated the geometric arrangement adopted by the complexes. Structures were proposed for each complex.
The Jun-dependent axon regeneration gene program: Jun promotes regeneration over plasticity.
Creators: name: Mason, Matthew RJ
name: van Erp, Susan
name: Wolzak, Kim
name: Behrens, Axel
name: Raivich, Gennadij
name: Verhaagen, Joost
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Model organisms
Tumour Biology
Gene Expression
Genetics & Genomics
Genome Integrity & Repair
Stem Cells

description: The regeneration-associated gene (RAG) expression program is activated in injured peripheral neurons after axotomy and enables long-distance axon re-growth. Over 1000 genes are regulated, and many transcription factors are upregulated or activated as part of this response. However, a detailed picture of how RAG expression is regulated is lacking. In particular the transcriptional targets and specific functions of the various transcription factors are unclear. Jun was the first regeneration-associated transcription factor identified and the first shown to be functionally important. Here we fully define the role of Jun in the RAG expression program in regenerating facial motor neurons. At 1, 4, and 14 days after axotomy, Jun upregulates 11%, 23% and 44% of the RAG program, respectively. Jun functions relevant to regeneration include cytoskeleton production, metabolic functions and cell activation, and the down-regulation of neurotransmission machinery. In silico analysis of promoter regions of Jun targets identifies stronger over-representation of AP1-like sites than CRE-like sites, although CRE sites were also over-represented in regions flanking AP1 sites. Strikingly, in motor neurons lacking Jun, an alternative SRF-dependent gene expression program is initiated after axotomy. The promoters of these newly expressed genes exhibit over-representation of CRE sites in regions near to SRF target sites. This alternative gene expression program includes plasticity-associated transcription factors, and leads to an aberrant early increase in synapse density on motor neurons. Jun thus has the important function in the early phase after axotomy of pushing the injured neuron away from a plasticity response and towards a regenerative phenotype.
Tafeln zur antiken griechischen Literaturgeschichte
Creators: name: (:Unkn) Unknown
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1800
Subjects: subject: 090

description: Geneaologien griechischer Autoren und Figuren; Zusammenstellung von Genres und Gattungen der antiken griechischen Literatur; Genealogie der Familie Napoleons
DETERMINING THE ENVIRONMENTAL WATER REQUIREMENT VIA HYDRAULIC AND HYDROLOGICAL METHODS
Creators: name: Ladan Abrari, Majed Parvan
Publisher: name: TuEngr Group
Year: 2019
Subjects: Environmental Flow Assessment
Water resource management
Environmental flow
Ecological management condition
Ecosystem water.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09A: 1-6.
Aqueous Two-Phase System as an Effective Tool for Purification of Phenolic Compounds from Fig Fruits (Ficus carica L.)
Creators: name: Feng, Yun-Chao
name: Li, Wen-Liang
name: Fa-Mei He
name: Kong, Tao-Tao
name: Huang, Xiao-Wei
name: Zhong-Hong Gao
name: Nai-Hao Lu
name: Li, Hai-Ling
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Information and Computing Sciences
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry

description: Fig fruits (Ficus carica L.) are an excellent source of phenolic compounds. However, the presence of free sugars affects the quality of phenolic compounds. In this study, aqueous two-phase system was selected for purification of the phenolic compounds. The optimization of system parameters rendered conditions (ethanol 18% (w/w), K2HPO4 25% (w/w), temperature 10-30ºC, and sample loading 3% (w/w)), under which more than 75% of phenolic compounds and 95% sugars were respectively recovered in the top and bottom phase. Moreover, some specific phenolic compounds content was enhanced and relatively high antioxidant activity was found after the purification process.
D5.2: Communities of Practice Report #2 - Documentation of Events and Achievements
Creators: name: Martínez, Manuel Bea
name: Goicolea, Elena
name: Wehbel, Marianne
name: Gnirss, Regina
name: Housni, Sofia
name: Tabuchi, Jean-Pierre
name: Greenhill, Barbara
name: Thining, Carsten
name: Bernardi, Marco
name: Dimova, Valentina
name: Stein, Ulf
name: Caradot, Nicolas
Publisher: name: Zenodo
Year: 2022

description: This report documents the activities and progress of the five local Communities of Practice (CoP) and the DWC project CoP.
 The first section describes the different CoPs operating in DWC including their key aims and goals.
 The second section reports the activities carried out and the progress achieved in the five local CoPs (i.e. DWC Berlin, DWC Copenhagen, DWC Milan, DWC Paris and DWC Sofia). Then, the two events organized for the Intra-Project CoP in the initial 30 months are documented.
 Finally, four annexes provide support information which has been shared with the CoP leaders to facilitate the setting up and operation of the CoPs.
description: Version (v0.2.0) submitted to EC.
Design and Evaluation of Chelating Resins through EDTA- and DTPA-Modified Ligands
Creators: name: G. Arrachart
name: A. Kenaan
name: S. Gracia
name: R. Turgis
name: V. Dubois
name: S. Pellet-Rostaing
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Ion-exchange resins through EDTA or DTPA moieties are synthesized and evaluated for the co-extraction of Cs+ and Sr2+ radionuclides for wastewater treatment. EDTA-bis(amide) and DTPA-bis(amide) derivatives bearing phenol or catechol moieties obtained from tyramine or dopamine, respectively, were used as building blocks to prepare ion-exchange resins. Their synthesis involved the condensation of formaldehyde with various phenolic rings, catechol (C), resorcinol (R), or calixresorcinarene (CR) under alkaline conditions. The resulting formo-phenolic-like resins have both ion-exchange and chelating groups in their structure and are indeed efficient in the remediation of Cs+ and Sr2+, even in salted aqueous solutions.
Transcriptional regulation of microRNA-100, −146a, and −150 genes by p53 and NFκB p65/RelA in mouse striatal STHdhQ7/ HdhQ7 cells and human cervical carcinoma HeLa cells
Creators: name: Jayeeta Ghose
name: N P Bhattacharyya
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: Hematology
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biophysics

description: MicroRNA (miRNA) genes generally share many features common to those of protein coding genes. Various transcription factors (TFs) and co-regulators are also known to regulate miRNA genes. Here we identify novel p53 and NFκB p65/RelA responsive miRNAs and demonstrate that these 2 TFs bind to the regulatory sequences of miR-100, −146a and −150 in both mouse striatal and human cervical carcinoma cells and regulate their expression. p53 represses the miRNAs while NFκB p65/RelA induces them. Further, we provide evidence that exogenous p53 inhibits NFκB p65/RelA activity by reducing its nuclear content and competing with it for CBP binding. This suggests for the existence of a functional cross-talk between the 2 TFs in regulating miRNA expression. Moreover, promoter occupancy assay reveals that exogenous p53 excludes NFκB p65/RelA from its binding site in the upstream sequence of miR-100 gene thereby causing its repression. Thus, our work identifies novel p53 and NFκB p65/RelA responsive miRNAs in human and mouse and uncovers possible mechanisms of co-regulation of miR-100. It is to be mentioned here that cross-talks between p53 and NFκB p65/RelA have been observed to define the outcome of several biological processes and that the pro-apoptotic effect of p53 and the pro-survival functions of NFκB can be largely mediated via the biological roles of the miRNAs these TFs regulate. Our observation with cell lines thus provides an important platform upon which further work is to be done to establish the biological significance of such co-regulation of miRNAs by p53 and NFκB p65/RelA.
COMPLICATIONS OF RUSSIAN INNOVATIVE DEVELOPMENT FINANCING
Creators: name: Kolesnikov A.V., Stepanyan T.M.
Publisher: name: TuEngr Group
Year: 2019
Subjects: Innovative development of agricultural industry, internal costs of scientific research, grant support of scientific research, high qualified personnel
agrifood policy.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09B: 1-11
NEURAL NETWORK IDENTIFICATION OF ELECTRIC POWER QUALITY INDICATORS OF COMPLEX POWER SYSTEMS
Creators: name: Tatyana Zhashkova *, Elena Meshcheryakova, Olga Yasarevskaya
Publisher: name: TuEngr Group
Year: 2019
Subjects: Neural network technology
Electric power quality indicators
Information system
power system
Engineering system
System for critical applications.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09C: 1-10
title: Les apports de la pratique régulière de la musique vocale en lien avec l'apprentissage du français et la participation sociale des élèves dans une classe du cycle 1
title: Élèves allophones, bilingues et francophones
titleType: Subtitle
title: Les apports de la pratique régulière de la musique vocale en lien avec l'apprentissage du français et la participation sociale des élèves dans une classe du cycle 1
titleType: AlternativeTitle
Creators: name: Delalay, Roxane
name: Seydoux, Joanne
Publisher: name: Unknown
Year: 0
Subjects: subject: musique
subject: musique vocale
subject: français
subject: langues
subject: allophonie
subject: bilinguisme
subject: interculturalité
subject: participation sociale

description: « Quelle contribution sociale et langagière la musique vocale apporte-t-elle à un enfant allophone, bilingue ou de langue maternelle française dans une classe d’élèves âgés de 4 à 6 ans en Suisse romande ?» voici la question de recherche à laquelle nous avons tenté de répondre par notre mémoire. Pour tenter d’y répondre, nous avons mis en place un dispositif précis et nous avons fait de nombreuses observations sur le terrain. Notre société se trouvant actuellement dans une réalité de pluralité socioculturelle sans cesse croissante, nous souhaitions nous intéresser aux apports de la pratique régulière de la musique vocale. Nous voulions éveiller la curiosité de nos élèves face à une langue ou une culture inconnue ainsi que les voir remettre en question leur langue première. Nous avons donc mené notre recherche dans deux classes de 1-2H du cycle 1 de deux régions différentes en instaurant des moments quotidiens de musique vocale. Nos observations portaient sur la progression au niveau de la participation sociale de l’enfant ainsi qu’au niveau de l’apprentissage du français et du développement de la conscience phonologique. De plus, nous pensions que la musique est un moyen efficace de travailler l’oral au cycle 1. Nous avons introduit plusieurs matériaux musicaux afin de pouvoir observer nos élèves à travers plusieurs situations et nous avons consulté plusieurs ouvrages afin de mieux comprendre les points théoriques à aborder. Nous vous présentons là le résultat de notre recherche et de nos expériences. Le sujet est vaste et aurait probablement nécessité une période d’observation plus longue pour en tirer une conclusion franche, mais, vous pourrez le constater, nous pouvons déjà en extraire plusieurs constats.
Splicing defects caused by exonic mutations in PKD1 as a new mechanism of pathogenesis in autosomal dominant polycystic kidney disease
Creators: name: Claverie-Martin, Felix
name: Gonzalez-Paredes, Francisco J
name: Ramos-Trujillo, Elena
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences

description: The correct splicing of precursor-mRNA depends on the actual splice sites plus exonic and intronic regulatory elements recognized by the splicing machinery. Surprisingly, an increasing number of examples reveal that exonic mutations disrupt the binding of splicing factors to these sequences or generate new splice sites or regulatory elements, causing disease. This contradicts the general assumption that missense mutations disrupt protein function and that synonymous mutations are merely polymorphisms. Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder caused mainly by mutations in the PKD1 gene. Recently, we analyzed a substantial number of PKD1 missense or synonymous mutations to further characterize their consequences on pre-mRNA splicing. Our results showed that one missense and 2 synonymous mutations induce significant defects in pre-mRNA splicing. Thus, it appears that aberrant splicing as a result of exonic mutations is a previously unrecognized cause of ADPKD.
Transcriptional regulation of microRNA-100, −146a, and −150 genes by p53 and NFκB p65/RelA in mouse striatal STHdhQ7/ HdhQ7 cells and human cervical carcinoma HeLa cells
Creators: name: Jayeeta Ghose
name: N P Bhattacharyya
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Computational Biology
subject: Hematology
subject: Cancer
subject: Developmental Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biophysics

description: ABSTRACTMicroRNA (miRNA) genes generally share many features common to those of protein coding genes. Various transcription factors (TFs) and co-regulators are also known to regulate miRNA genes. Here we identify novel p53 and NFκB p65/RelA responsive miRNAs and demonstrate that these two TFs bind to the regulatory sequences of miR-100, −146a and −150 in both mouse striatal and human cervical carcinoma cells and regulate their expression. p53 represses the miRNAs while NFκB p65/RelA induces them. Further, we provide evidence that exogenous p53 inhibits NFκB p65/RelA activity by reducing its nuclear content and competing with it for CBP binding. This suggests for the existence of a functional cross-talk between the two TFs in regulating miRNA expression. Moreover, promoter occupancy assay reveals that exogenous p53 excludes NFκB p65/RelA from its binding site in the upstream sequence of miR-100 gene thereby causing its repression. Thus, our work identifies novel p53 and NFκB p65/RelA responsive miRNAs in human and mouse and uncovers possible mechanisms of co-regulation of miR-100. It is to be mentioned here that cross-talks between p53 and NFκB p65/RelA have been observed to define the outcome of several biological processes and that the pro-apoptotic effect of p53 and the pro-survival functions of NFκB can be largely mediated via the biological roles of the miRNAs these TFs regulate. Our observation with cell lines thus provides an important platform upon which further work is to be done to establish the biological significance of such co-regulation of miRNAs by p53 and NFκB p65/RelA.
Aqueous two - phase system as an effective tool for purification of phenolic compounds from fig fruits (Ficus carica L.)
Creators: name: Feng, Yun-Chao
name: Li, Wen-Liang
name: Fa-Mei He
name: Kong, Tao-Tao
name: Huang, Xiao-Wei
name: Zhong-Hong Gao
name: Nai-Hao Lu
name: Li, Hai-Ling
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Information and Computing Sciences
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry

description: Fig fruits (Ficus carica L.) are excellent source of phenolic compounds. However, the presence of free sugars affects the quality of phenolic compounds. In this study, aqueous two-phase system was selected for purification of the phenolic compounds. The optimization of system parameters rendered conditions (ethanol 18% (w/w), K2HPO4 25% (w/w), temperature 10-30ºC and sample loading 3% (w/w)), under which more than 75% of phenolic compounds and 95% sugars were respectively recovered in the top and bottom phase. Moreover, some specific phenolic compounds content was enhanced and relatively high antioxidant activity was found after the purification process.
A Prime-Fractal Synthesis of Space, Time, Mass, and Energy
Creators: name: Gericke, Marco
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Higgs boson
subject: Quantum Gravity
subject: Mathematical Physics
subject: FOS: Mathematics
subject: Fractal Geometry

description: We investigate a prime-fractal extension of the Higgs mechanism, wherein the vacuum expectation value (VEV) and mass generation arise from discrete prime-density terms embedded in the Higgs potential. Within this framework, each particle’s mass is tied to a fractal dimension and prime-harmonic overlap, leading to novel scalar excitations beyond the Standard Model Higgs. Numerically, we identify three prominent peaks at approximately 541 GeV541\,\mathrm{GeV}541GeV, 809 GeV809\,\mathrm{GeV}809GeV, and 1.26 TeV1.26\,\mathrm{TeV}1.26TeV, predicted to manifest as Higgs-like resonances in collider data. These scalars derive from prime-lattice couplings that enrich the symmetry-breaking sector without introducing unnatural hierarchies. The simulation further suggests possible connections to dark-matter portals through subdominant prime-sum channels. Although phenomenological details depend on coupling constants and specific fractal dimensionalities, the distinct energy scales provide clear targets for ongoing and future collider experiments. By linking prime-based lattice structures to electroweak symmetry breaking, our model offers a testable path toward unifying number-theoretic structures with particle physics.

This project was developed by Marco Gericke, with structured assistance from a large language model. All scientific concepts and conclusions were generated, verified, and interpreted by the author.

Dedicated to Peter Plichta, who envisioned the code before it could be computed.
Design and evaluation of chelating resins through EDTA- and DTPA-modified ligands
Creators: name: G. Arrachart
name: A. Kenaan
name: S. Gracia
name: R. Turgis
name: V. Dubois
name: S. Pellet-Rostaing
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Ion-exchange resins through EDTA or DTPA moieties are synthesized and evaluated for the co-extraction of Cs+ and Sr2+ radionuclides for wastewater treatment. EDTA-bis(amide) and DTPA-bis(amide) derivatives bearing phenol or catechol moieties obtained from tyramine or dopamine, respectively, were used as building blocks to prepare ion-exchange resins. Their synthesis involved the condensation of formaldehyde with various phenolic rings, catechol (C), resorcinol (R), or calixresorcinarene (CR), under alkaline conditions. The resulting formo-phenolic-like resins have both ion-exchange and chelating groups in their structure and are indeed efficient in the remediation of Cs+ and Sr2+, even in salted aqueous solutions.
D6.3: Communication and Dissemination Strategy for digital-water.city - M30 update
Creators: name: Differdange, Camille
name: de Radzitzky, Chloé
name: Witpas, Katrien
name: Mauricio-Planas, Carla
Publisher: name: Zenodo
Year: 2022

description: The present communication strategy defines and establishes an effective framework which will guide the communication and dissemination activities throughout the project. This document presents the communication aims, strategy and the concrete means to be deployed.
description: Version (v0.3.0) submitted to EC.
Dominikus Kraschl: Indirekte Gotteserfahrung. Ihre Natur und Bedeutung für die theologische Erkenntnislehre (QD 282), Freiburg im Breisgau: Herder 2017
Creators: name: Biniek, Rafał
Publisher: name: Münchener Theologische Zeitschrift
Year: 2020

description: Münchener Theologische Zeitschrift, Bd. 69 Nr. 3 (2018)
Heat shock induces premature transcript termination and reconfigures the human transcriptome.
Creators: name: Cugusi, Simona
name: Mitter, Richard
name: Kelly, Gavin P
name: Walker, Jane
name: Han, Zhong
name: Pisano, Paola
name: Wierer, Michael
name: Stewart, Aengus
name: Svejstrup, Jesper Q
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: Model organisms
Biochemistry & Proteomics
Tumour Biology
Gene Expression
Genetics & Genomics
Genome Integrity & Repair
Chemical Biology & High Throughput
Computational & Systems Biology

description: The heat shock (HS) response involves rapid induction of HS genes, whereas transcriptional repression is established more slowly at most other genes. Previous data suggested that such repression results from inhibition of RNA polymerase II (RNAPII) pause release, but here, we show that HS strongly affects other phases of the transcription cycle. Intriguingly, while elongation rates increase upon HS, processivity markedly decreases, so that RNAPII frequently fails to reach the end of genes. Indeed, HS results in widespread premature transcript termination at cryptic, intronic polyadenylation (IPA) sites near gene 5'-ends, likely via inhibition of U1 telescripting. This results in dramatic reconfiguration of the human transcriptome with production of new, previously unannotated, short mRNAs that accumulate in the nucleus. Together, these results shed new light on the basic transcription mechanisms induced by growth at elevated temperature and show that a genome-wide shift toward usage of IPA sites can occur under physiological conditions.
Splicing defects caused by exonic mutations in PKD1 as a new mechanism of Pathogenesis in Autosomal Dominant Polycystic Kidney Disease
Creators: name: Claverie-Martin, Felix
name: Gonzalez-Paredes, Francisco J
name: Ramos-Trujillo, Elena
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences

description: The correct splicing of precursor-messenger RNA depends on the actual splice sites plus exonic and intronic regulatory elements recognized by the splicing machinery. Surprisingly, an increasing number of examples reveal that exonic mutations disrupt the binding of splicing factors to these sequences or generate new splice sites or regulatory elements, causing disease. This contradicts the general assumption that missense mutations disrupt protein function and that synonymous mutations are merely polymorphisms. Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder caused mainly by mutations in the PKD1 gene. Recently, we analyzed a substantial number of PKD1 missense or synonymous mutations to further characterize their consequences on pre-mRNA splicing. Our results showed that one missense and two synonymous mutations induce significant defects in pre-mRNAsplicing. Thus, it appears that aberrant splicing as a result of exonic mutations is a previously unrecognized cause of ADPKD.
FLEXURAL BEHAVIOR OF REINFORCED CONCRETE BEAMS STRENGTHENED WITH FERROCEMENT
Creators: name: Sayan Sirimontree, Boonsap Witchayangkoon
Publisher: name: TuEngr Group
Year: 2019
Subjects: Ferrocement beam
static four-point bending test
shear connectors
load-mid span deflection relationships
flexural load carrying capacity.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09D: 1-7
IMPORT SUBSTITUTION PROCESS IN THE RUSSIAN ECONOMY IN THE CONTEXT OF INTERNATIONAL SANCTIONS: ISSUES OF THEORY AND PRACTICE
Creators: name: L.E. Namyatova
Publisher: name: TuEngr Group
Year: 2019
Subjects: High-tech investment
International sanctions
protectionism
Mechanisms of import substitution
Strategy of import substitution
Domestic technology development.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09E: 1-13
A JUSTIFIED PLAN GRAPHICAL MATHEMATICAL ANALYSIS OF TRADITIONAL HOUSES IN MODERATE AND HUMID CLIMATE OF IRAN
Creators: name: Atikeh Mohammadi Nasab, Peiman Pilechiha. Mina Hajian
Publisher: name: TuEngr Group
Year: 2019
Subjects: Housing spatial configuration
Housing space parameters
Convex map
Integration value
Justified plan graph
Control value
Traditional house
Space syntax.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09F: 1-15
AN EXPERIMENT ON MEASUREMENT OF PAVEMENT ROUGHNESS VIA ANDROID-BASED SMARTPHONES
Creators: name: Piyasak Thiandee, Boonsap Witchayangkoon
Publisher: name: TuEngr Group
Year: 2019
Subjects: Pavement assessment
Pavement smoothness
RMS
Smartphone Accelerometer
Machine Learning
Pavement management.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09G: 1-9
IMPROVE QUALITY OF GLOBAL DEM FOR TOPOGRAPHIC MAPPING: CASE STUDY OF PETCHABURI PROVINCE, THAILAND
Creators: name: Kritsada Anantakarn, Phongphoom Sornchomkaew
Publisher: name: TuEngr Group
Year: 2019
Subjects: Radar
SRTM
GNSS
LBand
accuracy
GCP
topography
RMS error.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 9, 10A09H: 1-9
Animals in higher education settings: Do animal-assisted interventions improve mental and cognitive health outcomes of students?
Creators: name: Huber, Annalena
Publisher: name: figshare
Year: 2022
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Additional code and data used in the manuscript "Animals in higher education settings: Do animal-assisted interventions improve mental and cognitive health outcomes of students?". The manuscript has been submitted for publication.
Brief von Moritz Veit, Salomon Meyer und Joel Wolff Meyer von Älteste der Judenschaft an Leopold Zunz, 05.12.1842
Creators: name: (:Unkn) Unknown
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1842
Subjects: subject: 090

description: Antworten auf Fragen vom 24.11.1842, das Lehrerseminar betreffend
Brief von Strassmann an Salomon Neumann, 07.11.1875
Creators: name: (:Unkn) Unknown
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1875
Subjects: subject: 090

description: Mitteilung, dass Leopold Zunz' Ehrengehalt von 1800 Mark auf 2700 Mark erhöht worden ist
The building of nutrition institutions: a search for guiding principles based on SIDA experience in Africa
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Health Care

description: Greiner T. The building of nutrition institutions: a search for guiding principles based on SIDA experience in Africa. Paper prepared for the Advisory Group on Nutrition. Presented at the United Nations ACC Subcommittee on Nutrition, Sixteenth Session, Paris, February 19-23, 1990. This paper attempts to draw lessons learned from Sida support to four African countries that was aimed at building their capacity to solve their own nutrition problems--quite a rare form of development assistance. It seemed to work well in two caes; for some years Tanzania and Zimbabwe probably had the most technical capacity and ran some of the most successful nutrition programs in Africa.
Wilhelm Damberg; Ute Gause; Isolde Karle; Thomas Söding (HG.): Gottes Wort in der Geschichte. Reformation und Reform in der Kirche, Freiburg im Breisgau: Herder Verlag 2015
Creators: name: Mokry, Stephan
Publisher: name: Münchener Theologische Zeitschrift
Year: 2020

description: Münchener Theologische Zeitschrift, Bd. 69 Nr. 3 (2018)
The Choice by HIV-Positive Women to Exclusively Breastfeed Should Be Supported
Creators: name: Greiner, Ted
name: Sachs S
name: P, Morrison
Publisher: name: figshare
Year: 2015
Subjects: Medicine

description: Greiner T, Sachs S, Morrison P. The Choice by HIV-Positive Women to Exclusively Breastfeed Should Be Supported. Archives of Pediatrics & Adolescent Medicine 156(1):87-88, 2002. This letter was written in response to an article in which pediatricians seemingly proudly state that cases in which HIV-positive women expressed an intention to breast feed were referred to social authorities. Presumably this was considered child endangerment and subjected such mothers to loss of custody of their children. We argued that this is exaggerated and unnecessary.
Richtlinie: Oshtoran-Syndrom (H63D-Syndrom Typ-3)
Creators: name: Fachgesellschaften der H63D-Syndrom Forschung
Publisher: name: Zenodo
Year: 2024

description: Dies ist die offizielle Kurz-Guideline für Ärzte zum Oshtoran-Syndrom, wissenschaftlich auch als H63D-Syndrom Typ-3 bezeichnet. Stand 07/2024. Angenommen von den entscheidenden Fachgesellschaften.

Peer-Review abgeschlossen am 15. Juli 2024 durch Swabian Research ✓
title: Planting the modern city. The role of plants in the modernisation of Bogotá, Colombia (1880-1920)
Creators: name: Molina, Diego
Publisher: name: University of Reading
Year: 2023

description: Cities are inhabited not only by humans but also by plants. However, urban history has underplayed the role of plants in urban areas, largely perceiving them as a passive raw material in exclusively human-created cities. Drawing on the Latin American urban and gardening history, this thesis offers an alternative way of thinking about plants in cities, considering them as social actors actively involved in the symbolic and material development of the modern city. Specifically, this thesis examines how the modernisation of Bogotá involved a transformation in the ways of perceiving and interacting with plants, thereby engendering a change in the role of plants in the city. This research adopts a historical methodology based upon diverse sources, including newspaper articles, personal letters, maps, and photographs, as well as original sources such as literature and herbarium collections. The thesis comprises the following empirical chapters. Chapter Four explores the urban spaces where human-plant interactions were performed in pre-modern Bogotá. This chapter reveals that whereas upper class citizens experienced ornamental plants in domestic spaces such as patios and backyards, lower class citizens were in contact with an array of spontaneous and wild plants that they exploited based on vernacular knowledge. Chapter Five shows that the modernisation of Bogotá involved the creation of public green spaces based on the systematic use of plants, and how plants were endowed with new meanings and played an essential role in the creation of urban civility. Chapter Six shows how this transition to modern urban flora was enabled through the active intervention of people who acclimatised introduced plants and translated European ideas of green spaces into the local conditions to thereby contribute to the creation of a hybrid city characterised by a blend of floras. Finally, taking the use of eucalyptus in Bogotá as an example, Chapter Seven reveals the socioecological contradictions and conflicts that arose when pre-modern botanical knowledge and practices were replaced with modern ways of being-with plants in the city. The study reveals that the modernisation of Bogotá entailed a transformation in previous ways of using and understanding plants, and how the particularities of this emergent human-plant relationship endowed the city with a unique way of expressing its urban modernity. This thesis demonstrates that the city is not only a human-made product and elucidates the key role that plants have had in its historical development. The main contribution of this thesis is that it represents the first attempt to demonstrate that the transformation of green spaces as part of the city’s modernisation in Latin America was not only a matter of design but also entailed a restructuring of historically-produced relationships between people and plants
D7.4: IPR and innovation management
Creators: name: Caradot, Nicolas
Publisher: name: Zenodo
Year: 2022

description: D7.4 describes the innovation and Intellectual Property Rights (IPR) management procedures within DWC. It introduces the concepts of Intellectual Property (IP), the types of protection rights as well as the IPR rules in the project. It summarizes the key procedures introduced in the Grant Agreement and Consortium Agreement documents. Finally, it explains the role of the innovation and IPR manager and the detailed activities that will be carried out to foster innovation and secure the protection of our key results.
 Compared to the first version of May 2020, procedures and IPR management rules have not been changed and relation to WP5 (Plan for exploitation) has been specified.
description: Version (v0.2.0) submitted to EC.
The influence of infant food advertising on infant feeding practices in St. Vincent
Creators: name: Greiner, Ted
name: Latham, Michael C.
Publisher: name: figshare
Year: 2015
Subjects: Medicine

description: Greiner T and Latham M. The influence of infant food advertising on infant feeding practices in St. Vincent. International Journal of Health Services 12:53-75, 1982. This was the first and still perhaps most comprehnsive study to examine the impact of infant food advertising on infant feeding practices.
Evaluation of the impact of a food-based approach to solving vitamin A deficiency in Bangladesh
Creators: name: Greiner, Ted
name: SN, Mitra
Publisher: name: figshare
Year: 2015
Subjects: Medicine

description: Greiner T and Mitra SN. Evaluation of the impact of a food-based approach to solving vitamin A deficiency in Bangladesh. Food and Nutrition Bulletin 16(3):193-205, 1995. This was a large-scale evaluation, implementing a complex questionnaire twice on different probability samples in an intervention and a comparison district in Bangladesh. It measured the impact of the third year of a three-year food-based program. The consumption of green leaves (the most affordable vitamin A rich food) among young children was greatly increased in the intervention area while declining in the comparison area.
Issues potentially affecting the generalizability of Bland et al's findings
Creators: name: Greiner, Ted
Publisher: name: figshare
Year: 2015
Subjects: Medicine

description: Greiner T. Issues potentially affecting the generalizability of Bland et al's findings. Archives of Disease in Childhood Online, 17 November 2003. http://adc.bmjjournals.com/cgi/eletters/archdischild;88/9/778#564 Letter to the editor making a few additional points regarding breastfeeding definitions and HIV related to an excellent paper by Bland et al.