cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Soziale Nachhaltigkeit in der Beschaffung von IKT-Produkten : Forderung von Nachweisen zur Überprüfung der ILO-Kernarbeitsnormen
Creators: name: Biehl, Lara
Publisher: name: Weblaw
Year: 2024

description: Das revidierte Vergaberecht verlangt von Beschaffungsverantwortlichen, Nachhaltigkeitsaspekte in Ausschreibungen zu berücksichtigen. Dazu gehört auch die soziale Nachhaltigkeit, die vor allem die Einhaltung von Arbeitsschutzvorschriften umfasst. In einigen Branchen, z.B. im IKT-Sektor, sind Verstösse gegen die Normen der Internationalen Arbeitsorganisation (ILO) sehr ausgeprägt und erstrecken sich über alle Stufen der Lieferkette. Aus Gründen der Sorgfaltspflicht sind Beschaffungsstellen in der Verantwortung, die soziale Nachhaltigkeit in den Lieferketten der Produkte, die sie beschaffen, zu überprüfen und zu fördern. Der folgende Artikel zeigt einerseits auf, warum es notwendig ist, dass Beschaffungsstellen die Einhaltung der ILO-Kernarbeitsnormen überprüfen. Andererseits evaluiert er zwei Varianten, wie Beschaffer*innen eine solche Überprüfung im IKT-Bereich vornehmen können.
Arbeit nach 65: «Ja, gerne» oder «Nein, danke»?
Creators: name: Torben-Nielsen, Karen
name: N
Publisher: name: Berner Fachhochschule, Soziale Arbeit
Year: 2024

description: In der Schweiz kann sich fast die Hälfte der Arbeitnehmenden ab 45 Jahren vorstellen, nach der Pensionierung weiterzuarbeiten. Dennoch bleiben heute noch viele Fragen offen. Das Forschungsprojekt «Erwerbstätigkeit nach der Pensionierung» der Berner Fachhochschule hebt sechs wichtige gesellschaftlichen Fragen zum verlängerten Arbeitsleben hervor.
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial
Creators: name: Zhang, Huimin
name: Bao, Riyue
name: Hegde, Meenakshi
name: Nawas, Zeid
name: Chakraborty, Rikhia
name: Mehta, Birju
name: Ahmed, Nabil
name: Joseph, Sujith K.
name: Major, Angela
name: Hicks, M. John
name: Salem, Ahmed Hamed
name: Gad, Ahmed Z.
name: Gottschalk, Stephen
name: Wels, Winfried S.
name: Janeway, Katherine A.
name: Dotti, Gianpietro
name: Lapteva, Natalia
name: Sanber, Khaled
name: Dakhova, Olga
name: Shree, Ankita
name: Wu, Mengfen
name: Wang, Tao
name: Brenner, Malcolm K.
name: Bhat, Raksha R.
name: Robertson, Catherine
name: Campbell, Matthew
name: Kalra, Mamta
name: Thakkar, Sachin G.
name: Heslop, Helen E.
name: Mullikin, Dolores
name: Navai, Shoba
name: Gee, Adrian
name: Grilley, Bambi
name: DeRenzo, Christopher
name: Gerken, Claudia
name: Salsman, Vita S.
name: Mathew, Pretty R.
Publisher: name: Springer Nature
Year: 2024

description:
In this prospective, interventional phase 1 study for individuals with advanced sarcoma, we infused autologous HER2-specific chimeric antigen receptor T cells (HER2 CAR T cells) after lymphodepletion with fludarabine (Flu) ± cyclophosphamide (Cy): 1 × 108 T cells per m2 after Flu (cohort A) or Flu/Cy (cohort B) and 1 × 108 CAR+ T cells per m2 after Flu/Cy (cohort C). The primary outcome was assessment of safety of one dose of HER2 CAR T cells after lymphodepletion. Determination of antitumor responses was the secondary outcome. Thirteen individuals were treated in 14 enrollments, and seven received multiple infusions. HER2 CAR T cells expanded after 19 of 21 infusions. Nine of 12 individuals in cohorts A and B developed grade 1–2 cytokine release syndrome. Two individuals in cohort C experienced dose-limiting toxicity with grade 3–4 cytokine release syndrome. Antitumor activity was observed with clinical benefit in 50% of individuals treated. The tumor samples analyzed showed spatial heterogeneity of immune cells and clustering by sarcoma type and by treatment response. Our results affirm HER2 as a CAR T cell target and demonstrate the safety of this therapeutic approach in sarcoma. ClinicalTrials.gov registration: NCT00902044.
title: Eyes in the Heat: The Question Concerning Abstract Expressionism
Creators: name: Neofetou, Daniel
Publisher: name: Goldsmiths, University of London
Year: 2018
Subjects: subject: Abstract Expressionism, Clement Greenberg, Theodor W. Adorno, Maurice Merleau-Ponty, Leon Trotsky, Meyer Schapiro, Jackson Pollock, Joan Mitchell, Norman Lewis, Barnett Newman, Robert Motherwell, Cold War

description: Since the 1970s, revisionist art historians have elaborated how Abstract Expressionism was exhibited abroad by the post-war US establishment in order to characterise the movement, especially on Clement Greenberg’s account, as an artistic correlate to United States’ post-war dominance and worldwide imposition of capitalism. However, in this thesis, drawing on the theoretical resources of Theodor W. Adorno and Maurice Merleau-Ponty, I argue that Greenberg’s criticism in fact indicates how Abstract Expressionism stakes a claim against the rule of exchange-value. I interrogate the still prevalent notion that a development which Greenberg would retrospectively identify as a shift from Trotskyism to art-for-art’s-sake in the New York art scene of the ‘30s and ‘40s resulted in a movement, Abstract Expressionism, which lent itself to co-optation by US imperialism. I show that Abstract Expressionism’s deployment in efforts of cultural imperialism was certainly informed by Greenberg’s positioning of it as the pinnacle of the European modernist lineage due to its determinate negation of non-medium-specific elements. However, taking cues from philosopher J.M. Bernstein’s Adornian account of Abstract Expressionism, I then contend that this determinate negation is at the same time the affirmation of particularity delegitimated by capitalism. I then take recourse to both Greenberg’s and the artists’ accounts of their praxis, to show that it entailed a dialectic of construction and mimesis whereby the latter is guided by that which it forms. I then elaborate how, contrary to predominate accounts of Greenberg’s criticism, he in fact indicates the way in which the artworks invite mimetic comportment on the part of spectators, and engage cognition in a manner inextricable from corporeality. I contend that, thus, rather than buttressing the reified pluralism of capitalism, Abstract Expressionism both condemns capitalism’s disregard for corporeal subjects and prefigures the possibility of reconciliation which capitalism debars.
Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China
Creators: name: Zhang, Hua
name: Hou, Jinlin
name: Chen, Hui
name: Jin, Jie
name: Qi, Minghua
name: Duan, Chongyang
name: Tang, Weiming
name: Chan, Polin
name: Wang, Wei
name: Han, Guorong
name: Yao, Lyufeng
name: Sun, Tong
name: Li, Baijun
name: Cui, Fuqiang
name: Liu, Zhihua
name: Yin, Xueru
name: Mao, Qing
name: Gao, Qingwei
name: Gao, Yunfei
name: SHEILD Study Group
Publisher: name: Springer Nature
Year: 2024

description:
Reducing hepatitis B virus (HBV) mother-to-child transmission (MTCT) is a fundamental step toward the HBV elimination goal. The multicentred, multilevel SHIELD program aimed to use an intense intervention package to reduce HBV MTCT in China. This study was conducted in diverse health settings across China, encompassing 30,109 pregnant women from 178 hospitals, part of the interim analysis of stage II of the SHIELD program, and 8,642 pregnant women from 160 community-level health facilities in stage III of the SHIELD program. The study found that the overall MTCT rate was 0.23% (39 of 16,908; 95% confidence interval (CI): 0.16–0.32%) in stage II and 0.23% (12 of 5,290; 95% CI: 0.12–0.40%) in stage III. The MTCT rate was lower among participants who were compliant with the interventions (stage II: 0.16% (95% CI: 0.10–0.26%); stage III: 0.03% (95% CI: 0.00–0.19%)) than among those who were noncompliant (3.16% (95% CI: 1.94–4.85%); 1.91% (95% CI: 0.83–3.73%); P < 0.001). Our findings demonstrate that the comprehensive interventions among HBV-infected pregnant women were feasible and effective in dramatically reducing MTCT.
New Approaches of Planar Piezoelectric Ultrasonic Transducers for Effective Periodontal Scaling and Care
Creators: name: Hofmann, Martin
name: Stutzer, Diego
name: Nassisi, Quentin
name: Niederhauser, Thomas
name: Harmouch, Khaled
name: Spiezia, Giovanni
name: Eick, Sigrun
name: Burger, Jürgen
Publisher: name: IEEE
Year: 2024
Subjects: Ultrasonic instrumentation
Planar piezoelectric transducer
Periodontal debridement
Periodontitis

description: Besides dental caries, periodontitis and periimplant infections are the two most prevalent biofilm-associated oral diseases. Such chronic inflammation can cause destruction of the supporting gum tissue and eventually bone and tooth loss. To prevent oral pathologies, a professional routine for the removal of soft and hard bacterial deposits is recommended in supplement to daily oral hygiene. Manual instrumentation with curettes and ultrasonic scalers are used for prophylactic treatment. However, current ultrasonic instruments are limited in dimensions and operating frequencies. An innovative design for a novel dental scaler based on a planar ultrasonic transducer is introduced. The planar design allows the mass to be considerably reduced compared to a conventional Langevin transducer, resulting in a higher velocity to current ratio and thus an efficient but also sensitive scaler. The feasibility and potential of the planar scaler have already been confirmed by achieving displacement amplitudes of >50 μm at 28 kHz. In addition, the planar design allows for an alteration of the resonant frequency through minor geometric adjustments to the horn. The design was modified for 20 and 40 kHz to obtain information about the most advantageous operating frequency, through both electromechanical characterisation and an in vitro setup with an artificial biofilm pocket model.
title: Theatricalizing Dissent: An Examination of the Methodology and Efficacy of Performance in Contemporary Political Protest
Creators: name: Rees, Sian
Publisher: name: Goldsmiths, University of London
Year: 2018
Subjects: subject: Theatre, Performance, Dissent, Theatrical Dissent, Protest, Contemporary Protest, Austerity, Creative Activism, Protest Performance, Artistic Activism, Climate Justice, Democracy, Ecology, Guerrilla Performance, Interventions, Rough Music, Play as Resistance, Play and Gaming, Temporary Autonomous Zone, BP or Not BP, Liberate Tate, Art Not Oil, Coney, Laboratory of Insurrectionary Imagination, Burning Man, Occupy, Occupy London, Practice as Research

description: Activists and artists are consciously bringing theatre to the forefront of contemporary protest interventions. This thesis examines the efficacy of performative modes in acts of theatrical dissent. 

My research is based on case studies from the UK, Paris, Belgium, and the United States which staged interventions, often experimenting with different democratic models of relationships and often prefiguratively, and which campaigned on social, economic, and political issues: against austerity, climate injustice, and consumerism. They employed diverse performative modes: Rough Music, Guerrilla Performance, Play and Gaming, and the creation of a Temporary Autonomous Zone. The Practice as Research component provided the perspective of an insider through my participation in theatrical dissent organized by artists and activists, and through my own work, HOUND (2016), which incorporated a variety of performative modes previously identified as efficacious.

Activists seek to expose, through their own performances, the performances of power and legitimacy staged by corporations and governments; and to advocate the necessity for change. Some elements of these modes may militate against political efficacy, whilst others contribute towards it by working to avoid a crude and heavy-handed didacticism by encouraging spectators to collaborate in the performance. I identify and analyze the elements of performance modes which may be conducive in supporting and sustaining activists; and those which may ignite an interest in a cause in spectators. To be a dissenter, to some extent, is to be an outsider, one who questions society’s norms and mores. I argue that theatrical devices (such as ‘making strange’ the everyday), provide the necessary distancing for audiences and participants alike to question the ‘normal’. This is the first step in an exploration of dissent provided by theatre’s ability, when staged as dissent, to create new political realities.
Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population
Creators: name: Lichtenstein, Paul
name: Hottenga, Jouke-Jan
name: Wu, Hei Man
name: Meier, Sandra M.
name: Mattheisen, Manuel
name: Pool, René
name: Crowley, James J.
name: Antonyan, Lilit
name: Larsson, Henrik
name: Lemire, Mathieu
name: Schachar, Russell
name: Boomsma, Dorret I.
name: Ivanov, Volen Z.
name: Mataix-Cols, David
name: Silzer, Talisa
name: Rück, Christian
name: Iyegbe, Conrad
name: Crosbie, Jennifer
name: Strom, Nora I.
name: Arnold, Paul D.
name: Magnusson, Patrik
name: Cath, Danielle
name: Smit, Dirk J. A.
name: Burton, Christie L.
Publisher: name: Springer Nature
Year: 2024

description:
While 1–2% of individuals meet the criteria for a clinical diagnosis of obsessive-compulsive disorder (OCD), many more (~13–38%) experience subclinical obsessive-compulsive symptoms (OCS) during their life. To characterize the genetic underpinnings of OCS and its genetic relationship to OCD, we conducted the largest genome-wide association study (GWAS) meta-analysis of parent- or self-reported OCS to date (N = 33,943 with complete phenotypic and genome-wide data), combining the results from seven large-scale population-based cohorts from Sweden, the Netherlands, England, and Canada (including six twin cohorts and one cohort of unrelated individuals). We found no genome-wide significant associations at the single-nucleotide polymorphism (SNP) or gene-level, but a polygenic risk score (PRS) based on the OCD GWAS previously published by the Psychiatric Genetics Consortium (PGC-OCD) was significantly associated with OCS (Pfixed = 3.06 × 10−5). Also, one curated gene set (Mootha Gluconeogenesis) reached Bonferroni-corrected significance (Ngenes = 28, Beta = 0.79, SE = 0.16, Pbon = 0.008). Expression of genes in this set is high at sites of insulin mediated glucose disposal. Dysregulated insulin signaling in the etiology of OCS has been suggested by a previous study describing a genetic overlap of OCS with insulin signaling-related traits in children and adolescents. We report a SNP heritability of 4.1% (P = 0.0044) in the meta-analyzed GWAS, and heritability estimates based on the twin cohorts of 33–43%. Genetic correlation analysis showed that OCS were most strongly associated with OCD (rG = 0.72, p = 0.0007) among all tested psychiatric disorders (N = 11). Of all 97 tested phenotypes, 24 showed a significant genetic correlation with OCS, and 66 traits showed concordant directions of effect with OCS and OCD. OCS have a significant polygenic contribution and share genetic risk with diagnosed OCD, supporting the hypothesis that OCD represents the extreme end of widely distributed OCS in the population.
Impact of dietary counselling on allergic reactions in children with food allergy
Creators: name: Eisenblaetter, Julia
name: Stephens-Metcalfe, Nia
name: Meichtry, André Anton
name: Van Der Horst, Klazine
name: Roduit, Caroline
name: Koehli, Alice
name: Enders, Felicitas Bellutti
name: Skypala, Isabel
name: Hickson, Mary
Publisher: name: Springer Science and Business Media LLC
Year: 2024

description: Purpose Dietary counselling in the field of food allergy aims primarily to empower individuals to prevent allergic reactions, but its impact on allergic reactions remains unclear. This study examined the impact of dietary counselling and other factors on allergic reactions in children with food allergies. Methods In a multicentre study, parents of children (0–10 years) recently diagnosed with food allergies completed online questionnaires collecting data on subsequent allergic reactions. Data were collected at baseline and at 3, 6 and 12 months postdiagnosis. We fitted a negative binominal model to the data in order to quantify effects of counselling, time period and multiple food allergies on food allergy reaction rates. Results Among the 48 enrolled children, 31 encountered a total of 85 food allergic reactions. The monthly reaction rate decreased from 0.28 in the first 3 months to 0.07 between 6 and 12 months. Children receiving counselling from a dietitian demonstrated a lower ratio (incidence rate ratio [IRR] = 0.37, confidence interval [CI] 0.19–0.72, p = 0.004). Those with more than three food allergies have an increased ratio compared to those with one to two food allergies (IRR = 6.18, CI 2.75–3.89, p < 0.001). Conclusion Individual dietary counselling has the potential to prevent subsequent allergic reactions after diagnosis as it reduced the risk of allergic reactions by 63%. This impact might be most pronounced in the early months following diagnosis. Children with multiple food allergies are at a higher risk of allergic reactions and should, therefore, be prioritized to receive dietary counselling.
Mental health of individuals at increased suicide risk after hospital discharge and initial findings on the usefulness of a suicide prevention project in Central Switzerland
Creators: name: Werdin, Sophia
name: Fink, Günther
name: Rajkumar, Sarah
name: Durrer, Michael
name: Gurtner, Caroline
name: Harbauer, Gregor
name: Warnke, Ingeborg
name: Wyss, Kaspar
Publisher: name: Frontiers Research Foundation
Year: 2024

description: Background: Supporting individuals in managing their suicidality can prevent suicidal behavior. This study evaluated the suicide prevention project SERO, which was launched in Central Switzerland in 2021. SERO comprises four components: the suicide risk assessment technique PRISM-S, a personal safety plan, mental health first aid courses for relatives, and a self-management app. We assessed the mental health of individuals at increased suicide risk after hospital discharge and evaluated the usage and usefulness of SERO components. Methods: A cross-sectional study targeted former patients of Lucerne Psychiatry with an increased suicide risk. Between March 2023 and March 2024, we collected data from 24 individuals through a questionnaire administered six months post-discharge. Descriptive statistics characterized sociodemographics, assessed self-efficacy, self-management, and health literacy, and analyzed the usage and usefulness of SERO components. Associations between the usage of SERO components and mental health outcomes were investigated using Wilcoxon rank sum tests. Results: Mental health assessments indicated, on average, low to moderate levels of self-efficacy, self-management, and health literacy, with substantial variations across individuals. Participants’ exposure to SERO components varied: 83% used PRISM-S for suicide risk assessment, 67% developed a personal safety plan, 38% used the SERO app, and 8% reported that their relatives participated in a mental health first aid course. 50% of safety plan users and 44% of SERO app users found the tools helpful before or during a suicidal crisis. 78% of SERO app users would recommend the app to others. Conclusion: Low to moderate levels of self-efficacy, self-management, and health literacy underscore the need for targeted interventions to support individuals at suicide risk. Positive feedback on the personal safety plan and the SERO app suggests their potential effectiveness in helping individuals manage their suicidality. Therefore, integrating structured measures for promoting self-management into standard care protocols in psychiatric hospitals and into patients’ lives may contribute to preventing suicides. The main limitation of our study is its small sample size. Future larger-scale studies should investigate user experiences in detail, assess the causal effects of SERO components on specific mental health and suicide outcomes, and evaluate the cost-effectiveness of each component separately and in combination.
Search for charged excited states of dark matter with KamLAND-Zen
Creators: name: Sakai, T.
name: Weerman, K.M.
name: Learned, J.G.
name: Umehara, S.
name: Nakajima, R.
name: Tornow, W.
name: Kotera, K.
name: Grant, C.
name: Mitsui, T.
name: Berger, B.E.
name: Gando, A.
name: Li, A.
name: Axani, S.N.
name: Enomoto, S.
name: Efremenko, Y.
name: Ishidoshiro, K.
name: Kishimoto, Y.
name: Decowski, M.P.
name: Tamae, K.
name: Kawada, N.
name: Karwowski, H.J.
name: Watanabe, K.
name: Dell'Oro, S.
name: Hachiya, T.
name: Koga, M.
name: Eizuka, M.
name: Kurasawa, M.
name: Fu, Z.
name: O'Donnell, T.
name: Inoue, K.
name: Hata, K.
name: Abe, S.
name: Shoji, R.
name: Watanabe, H.
name: Miyake, H.
name: Hosokawa, K.
name: Detwiler, J.A.
name: Smolsky, J.
name: Ichimura, K.
name: Winslow, L.A.
name: Nakamura, R.
name: Shimizu, I.
name: Fushimi, K.
name: Kamei, Y.
name: Futagi, S.
name: Fujikawa, B.K.
name: Suzuki, A.
name: Maricic, J.
name: Nakamura, K.
name: Shirai, J.
name: Morita, D.
name: Urano, Y.
name: Nakane, J.
name: Takeuchi, A.
name: Ieki, S.
name: Nakamura, R.
name: Gando, Y.
name: Ikeda, H.
name: Shiraishi, K.
name: Obara, S.
name: Nakahata, T.
name: Ozaki, H.
name: Yoshida, S.
name: Goto, S.
name: Ichikawa, A.
name: Song, H.
name: Markoff, D.M.
Publisher: name: Elsevier
Year: 2024

description:
Particle dark matter could belong to a multiplet that includes an electrically charged state. WIMP dark matter ( χ 0 ) accompanied by a negatively charged excited state ( χ − ) with a small mass difference (e.g. < 20 MeV) can form a bound-state with a nucleus such as xenon. This bound-state formation is rare and the released energy is O ( 1 − 10 ) MeV depending on the nucleus, making large liquid scintillator detectors suitable for detection. We searched for bound-state formation events with xenon in two experimental phases of the KamLAND-Zen experiment, a xenon-doped liquid scintillator detector. No statistically significant events were observed. For a benchmark parameter set of WIMP mass m χ 0 = 1 TeV and mass difference Δ m = 17 MeV, we set the most stringent upper limits on the recombination cross section times velocity 〈 σ v 〉 and the decay-width of χ − to 9.2 × 10 − 30 c m 3 / s and 8.7 × 10 − 14 GeV, respectively at 90% confidence level.
Supplemental Material - STI prevalence, incidence, and partner notification among women in a periconception HIV prevention program in Uganda
Creators: name: Chitneni, Pooja
name: Muyindike, Winnie
name: Bwana, Mwebesa Bosco
name: Owembabazi, Moran
name: O’Neil, Kasey
name: Kalyebara, Paul Kato
name: Hedt-Gauthier, Bethany
name: Bangsberg, David R
name: Marrazzo, Jeanne M
name: Kaida, Angela
name: Haberer, Jessica E
name: Matthews, Lynn T
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplemental Material for STI prevalence, incidence, and partner notification among women in a periconception HIV prevention program in Uganda by Pooja Chitneni, Winnie Muyindike, Mwebesa Bosco Bwana, Moran Owembabazi, Kasey O’Neil, Paul Kato Kalyebara, Bethany Hedt-Gauthier, David R Bangsberg, Jeanne M Marrazzo, Angela Kaida, Jessica E Haberer and Lynn T Matthews in International Journal of STD & AIDS
Die Rolle der Frau in der Waldwirtschaft
Creators: name: Möller, Sharon
name: Coleman Brantschen, Evelyn Constance
name: Wilkes-Allemann, Jerylee
Publisher: name: Schweizerischer Forstverein
Year: 2024

description: 2001 wurden im Auftrag des Bundesamts für Umwelt, Wald und Landschaft (BUWAL, heute BAFU) Hürden, Chancen und Perspektiven der Frauen in der Waldwirtschaft untersucht. Heute soll eruiert werden, welche Rolle die Frau in der Waldwirtschaft im internationalen Kontext einnimmt und welche Förderprogramme und Methoden existieren. Zudem beleuchten wir in diesem Beitrag die Rolle der Frau in der Schweizer Waldwirtschaft. Dazu haben wir wissenschaftliche Publikationen von 2001 bis 2023 analysiert.
Entwicklung und Prüfung eines praxistauglichen Tools zur Herleitung von Steinschlag-Ablöseszenarien
Creators: name: Moos, Christine
name: Bontognali, Zeno
name: Hantz, Didier
name: Jaboyedoff, Michel
name: Dorren, Luuk
Publisher: name: Fachleute Naturgefahren Schweiz FAN
Year: 2024

description: Nachvollziehbare und objektive Steinschlag- Ablöseszenarien erhöhen die Akzeptanz im Steinschlag-Risikomanagement. In diesem Projekt wurde eine Methode basierend auf «Potenzgesetz-Verteilungen» zur Herleitung von Ablöseszenarien in 15 Untersuchungs- gebieten überprüft. Basierend darauf wurde das Tool «RockFreq» (RFT) erstellt, das die Herleitung von Ablöseszenarien unterstützen soll. Der Vergleich der Blockgrössen basie- rend auf dem RFT mit Szenarien aus Gefah- renanalysen zeigte, dass erstere grösser sind für die grösseren Wiederkehrperioden. Dies ist darauf zurückzuführen, dass die Szenarien der Gefahrenanalysen zumeist keiner Potenz- gesetz-Verteilung folgen. Ein Vorteil des RFT ist, dass es die Grösse einer Felswand explizit berücksichtigt, da diese die Szenarien stark beeinflusst. Unsicherheiten bestehen in der Parameterschätzung für die Felswand sowie im maximale Blockvolumen. Im Allgemeinen ist das RFT ein objektiver Ansatz, um Stein- schlag-Ablöseszenarien zu bestimmen und kann mit relativ geringem Aufwand angewen- det werden. In einem nächsten Schritt soll das RFT in weiteren Fallstudien validiert werden.
title: Report on Lessons Learned and Best Practices
title: TRAIN4EU+ Deliverable 7.5
titleType: Subtitle
Creators: name: University of Copenhagen
Publisher: name: Zenodo
Year: 2023
Subjects: lessons learned
best practices
ERA policy briefs
transformation modules
research support

description: TRAIN4EU+ deliverable D7.5 is the Publications on lessons learned and best practices in Work Package 7 "Dissemination, Exploitation and Communication". Focus areas include Main Learnings and Project Progress in TRAIN4EU+; Publications on lessons learned and best practices in TRAIN4EU+; ERA Policy Briefs; SwafS Cross Alliances Forum 2023.
sj-docx-1-pie-10.1177_09544089221110746 - Supplemental material for Hydromagnetic CuO-H2O nanofluid transportation through irreversibility analysis
Creators: name: Ibrahim, SM
name: Shehzad, SA
name: Mabood, F
name: Badruddin, IA
name: Ambreen, T
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-docx-1-pie-10.1177_09544089221110746 for Hydromagnetic CuO-H2O nanofluid transportation through irreversibility analysis by SM Ibrahim, SA Shehzad, F Mabood and IA Badruddin, T Ambreen in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering
Research gaps and priorities for quantitative microbial risk assessment (QMRA)
Creators: name: Dean, Kara
name: Gerrity, Daniel
name: Murphy, Heather
name: Jahne, Michael
name: Nejadhashemi, A. Pouyan
name: Dunbar, Gwyneth
name: Harrison, Joanna Ciol
name: Zimmer‐Faust, Amy
name: Aw, Tiong Gim
name: Oryang, David
name: Pasek, Emily
name: Weir, Mark
name: Owusu‐Ansah, Emmanuel de‐Graft Johnson
name: Solo‐Gabriele, Helena
name: Schoen, Mary
name: Eisenberg, Joseph N. S.
name: Smeets, Patrick W. M. H.
name: Gurian, Patrick L.
name: Haas, Charles N.
name: Mraz, Alexis
name: Julian, Timothy R.
name: Gibson, Jacqueline MacDonald
name: Jones, Rachael M.
name: Meschke, J. Scott
name: Pradhan, Abani K.
name: Medema, Gertjan
name: Razzolini, Maria Tereza Pepe
name: Hamilton, Kerry A.
name: Li, Yanbin
name: Li, Hongwan
name: Bibby, Kyle
name: Libarkin, Julie
name: Verhougstraete, Marc
name: Mitchell, Jade
name: Wilson, Amanda M.
name: Williams, Clinton
name: Emelko, Monica
name: Brown, Joe
name: Soller, Jeffrey
name: Ryan, Michael O.
name: Rose, Joan B.
name: Alja'fari, Jumana
name: Hartnett, Emma
name: Bivins, Aaron
Publisher: name: Wiley
Year: 2024

description:
The coronavirus disease 2019 pandemic highlighted the need for more rapid and routine application of modeling approaches such as quantitative microbial risk assessment (QMRA) for protecting public health. QMRA is a transdisciplinary science dedicated to understanding, predicting, and mitigating infectious disease risks. To better equip QMRA researchers to inform policy and public health management, an Advances in Research for QMRA workshop was held to synthesize a path forward for QMRA research. We summarize insights from 41 QMRA researchers and experts to clarify the role of QMRA in risk analysis by (1) identifying key research needs, (2) highlighting emerging applications of QMRA; and (3) describing data needs and key scientific efforts to improve the science of QMRA. Key identified research priorities included using molecular tools in QMRA, advancing dose-response methodology, addressing needed exposure assessments, harmonizing environmental monitoring for QMRA, unifying a divide between disease transmission and QMRA models, calibrating and/or validating QMRA models, modeling co-exposures and mixtures, and standardizing practices for incorporating variability and uncertainty throughout the source-to-outcome continuum. Cross-cutting needs identified were to: develop a community of research and practice, integrate QMRA with other scientific approaches, increase QMRA translation and impacts, build communication strategies, and encourage sustainable funding mechanisms. Ultimately, a vision for advancing the science of QMRA is outlined for informing national to global health assessments, controls, and policies.
Additional file 1 of Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Creators: name: Lu, Yang
name: Wu, Yu-Wei
name: Pu, Jiu
name: Wu, Qiong-Feng
name: Dong, Qian
name: Zhao, Ning
name: Li, Gui-Rong
name: Du, Yi-Mei
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 1.
Anton Freiherr v. Ow., Hom der falsche Prophet aus noachitischer Zeit
Creators: name: István, Sulyok
Publisher: name: Römische Quartalschrift
Year: 1970

description: Römische Quartalschrift, Bd. 20 Nr. 1 (1906): Römische Quartalschrift, Band 20, Heft 1
Systematic data quality assessment of electronic health record data to evaluate study-specific fitness: Report from the PRESERVE research study
Creators: name: Denburg, Michelle R.
name: Bailey, L. Charles
name: Rosenman, Marc
name: Dickinson, Kimberley
name: Boss, Samuel
name: Lemas, Dominick J.
name: Razzaghi, Hanieh
name: Huang, Yungui
name: Chrischilles, Elizabeth A.
name: Matthews, Kevin
name: Davies, Amy Goodwin
name: Lehmann, Harold
name: Mendonca, Eneida A.
name: Hanauer, David
name: Ranade, Daksha
name: Chen, Yong
name: Forrest, Christopher B.
name: Walters, Kellie
name: Katsoufis, Chryso
name: Morse, Keith
name: Ilunga, K. T. Sandra
name: Bunnell, H. Timothy
name: Taylor, Bradley
Publisher: name: Public Library of Science (PLoS)
Year: 2024

description:
Study-specific data quality testing is an essential part of minimizing analytic errors, particularly for studies making secondary use of clinical data. We applied a systematic and reproducible approach for study-specific data quality testing to the analysis plan for PRESERVE, a 15-site, EHR-based observational study of chronic kidney disease in children. This approach integrated widely adopted data quality concepts with healthcare-specific evaluation methods. We implemented two rounds of data quality assessment. The first produced high-level evaluation using aggregate results from a distributed query, focused on cohort identification and main analytic requirements. The second focused on extended testing of row-level data centralized for analysis. We systematized reporting and cataloguing of data quality issues, providing institutional teams with prioritized issues for resolution. We tracked improvements and documented anomalous data for consideration during analyses. The checks we developed identified 115 and 157 data quality issues in the two rounds, involving completeness, data model conformance, cross-variable concordance, consistency, and plausibility, extending traditional data quality approaches to address more complex stratification and temporal patterns. Resolution efforts focused on higher priority issues, given finite study resources. In many cases, institutional teams were able to correct data extraction errors or obtain additional data, avoiding exclusion of 2 institutions entirely and resolving 123 other gaps. Other results identified complexities in measures of kidney function, bearing on the study's outcome definition. Where limitations such as these are intrinsic to clinical data, the study team must account for them in conducting analyses. This study rigorously evaluated fitness of data for intended use. The framework is reusable and built on a strong theoretical underpinning. Significant data quality issues that would have otherwise delayed analyses or made data unusable were addressed. This study highlights the need for teams combining subject-matter and informatics expertise to address data quality when working with real world data.
Additional file 1 of Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment
Creators: name: Cabrera-Pérez, Raquel
name: Ràfols-Mitjans, Alexis
name: Roig-Molina, Ángela
name: Beltramone, Silvia
name: Vives, Joaquim
name: Batlle-Morera, Laura
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1: Table S1. Distribution and justification of the experimental study groups. Composition, nature, and justification of the different experimental treatment groups included in the study. N, number of animals; TI, Test Item; RI, Reference Item; FFly, FireFly; NLuc, NanoLuc; NT, Non-Treated; BLI, Bioluminescence Imaging.
title: Searching for Manila : Personal and Political Journeys in an Asian Megacity
Creators: name: Sykes, Thomas
Publisher: name: Goldsmiths, University of London
Year: 2018
Subjects: subject: Travel writing, Postcolonialism, Literary journalism, Asia, Philippines, Manila

description: Searching for Manila: Personal and Political Journeys in an Asian Megacity is an autobiographical travelogue based on a period I spent living and working in Manila, the Philippines in 2009-10, and on two subsequent visits to the city. The book, which is slightly abridged for this submission, addresses themes both personal (such as the difficult processes of deciding what to do with my life, of falling in love and of becoming a surrogate father) and political (the struggles of marginalised communities against official oppression, the impact of neo-liberalism on various aspects of Philippine society and the ideological reasons why Filipinos selectively remember national traumas). I interweave my lived, empirical experiences of people and places with data researched from other Manila-focused texts both historical and contemporary: novels, memoirs, travel books, media reports, statistical surveys and historiographical analyses.
 
The critical commentary element of my thesis begins with an analysis of what I term ‘Manilaism’, a trajectory of Anglo-American travel writing, literary journalism and realist fiction set in Manila dating from the mid-Victorian era to the twenty-first century, and goes on to argue that Searching for Manila contests the reactionary and ethnocentric assumptions of these texts by employing a variety of research methods, narrative strategies and linguistic devices. The result of these creative decisions has been to situate Searching for Manila as a ‘radical travelogue’; that is to say radical according to both the formal and political senses of the word: my mobilisation of parody, self-reflexivity and inter-textuality are complemented by my endeavours to evoke Manila through the lens of my leftist commitments to peace, social equality, economic justice, anti-racism and anti-imperialism.
Active Sourcing Tools in der Schweiz: Zwischen Effizienz und Fairness
Creators: name: Straub, Caroline
name: Kurpicz-Briki, Mascha
Publisher: name: Berner Fachhochschule, Wirtschaft
Year: 2024

description: Grosse Schweizer Unternehmen setzen verstärkt auf digitale Tools im Recruiting – von LinkedIn Recruiter bis ChatGPT. Doch wie effektiv sind diese Werkzeuge wirklich? Caroline Straub und Mascha Kurpicz-Briki haben untersucht, wie verbreitet Active Sourcing Tools sind, wo ihre Stärken liegen und ob es zu Verzerrungen bzw. Benachteiligung von Personengruppen im digitalen Recruiting kommt.
sj-pdf-1-jdr-10.1177_00220345221105816 – Supplemental material for Spatiotemporal MicroRNA-Gene Expression Network Related to Orofacial Clefts
Creators: name: Yan, F.
name: Simon, L.M.
name: Suzuki, A.
name: Iwaya, C.
name: Jia, P.
name: Iwata, J.
name: Zhao, Z.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-pdf-1-jdr-10.1177_00220345221105816 for Spatiotemporal MicroRNA-Gene Expression Network Related to Orofacial Clefts by F. Yan, L.M. Simon, A. Suzuki, C. Iwaya, P. Jia, J. Iwata and Z. Zhao in Journal of Dental Research
Daratumumab-based quadruplet therapy for transplant-eligible newly diagnosed multiple myeloma with high cytogenetic risk
Creators: name: Cortoos, Annelore
name: Rodriguez, Cesar
name: Jakubowiak, Andrzej
name: Wildes, Tanya M.
name: Hari, Parameswaran
name: Bumma, Naresh
name: Orlowski, Robert Z.
name: Chhabra, Saurabh
name: Dhakal, Binod
name: Shah, Nina
name: Chari, Ajai
name: Medvedova, Eva
name: Richardson, Paul G.
name: Callander, Natalie S.
name: Lin, Thomas S.
name: Silbermann, Rebecca
name: Voorhees, Peter M.
name: Costa, Luciano J.
name: Usmani, Saad Z.
name: Bal, Susan
name: Dholaria, Bhagirathbhai R.
name: Nathwani, Nitya
name: Anderson, Larry D.
name: Giri, Smith
name: Shain, Kenneth H.
name: Laubach, Jacob
name: Sborov, Douglas W.
name: Holstein, Sarah A.
name: Costello, Caitlin
name: Godby, Kelly N.
name: Schmidt, Timothy M.
name: Pei, Huiling
name: Patel, Sharmila
name: Reeves, Brandi
name: Cowan, Andrew J.
name: Kaufman, Jonathan L.
Publisher: name: Springer Nature
Year: 2024

description:
In the MASTER study (NCT03224507), daratumumab+carfilzomib/lenalidomide/dexamethasone (D-KRd) demonstrated promising efficacy in transplant-eligible newly diagnosed multiple myeloma (NDMM). In GRIFFIN (NCT02874742), daratumumab+lenalidomide/bortezomib/dexamethasone (D-RVd) improved outcomes for transplant-eligible NDMM. Here, we present a post hoc analysis of patients with high-risk cytogenetic abnormalities (HRCAs; del[17p], t[4;14], t[14;16], t[14;20], or gain/amp[1q21]). Among 123 D-KRd patients, 43.1%, 37.4%, and 19.5% had 0, 1, or ≥2 HRCAs. Among 120 D-RVd patients, 55.8%, 28.3%, and 10.8% had 0, 1, or ≥2 HRCAs. Rates of complete response or better (best on study) for 0, 1, or ≥2 HRCAs were 90.6%, 89.1%, and 70.8% for D-KRd, and 90.9%, 78.8%, and 61.5% for D-RVd. At median follow-up (MASTER, 31.1 months; GRIFFIN, 49.6 months for randomized patients/59.5 months for safety run-in patients), MRD-negativity rates as assessed by next-generation sequencing (10–5) were 80.0%, 86.4%, and 83.3% for 0, 1, or ≥2 HRCAs for D-KRd, and 76.1%, 55.9%, and 61.5% for D-RVd. PFS was similar between studies and superior for 0 or 1 versus ≥2 HRCAs: 36-month PFS rates for D-KRd were 89.9%, 86.2%, and 52.4%, and 96.7%, 90.5%, and 53.5% for D-RVd. These data support the use of daratumumab-containing regimens for transplant-eligible NDMM with HCRAs; however, additional strategies are needed for ultra-high–risk disease (≥2 HRCAs).
Towards Adaptive Mils System: Model- Based Design, Verification And Run-Time Adaptation
Creators: name: Cimatti, Alessandro
name: DeLong, Rance
name: Stojic, Ivan
name: Tonetta, Stefano
Publisher: name: Zenodo
Year: 2018
Subjects: MILS

description: Presentation to conference paper: Towards adaptive MILS System: Model- Based Design, Verification and Run-Time Adaptation
Topological operators, noninvertible symmetries and decomposition
Creators: name: Sharpe, E.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we discuss the relationship between noninvertible topological operators, one-form symmetries, and decomposition of two-dimensional quantum field theories, focusing on two-dimensional orbifolds with and without discrete torsion. As one component of our analysis, we study the ring of dimension-zero operators in two-dimensional theories exhibiting decomposition. From a commutative algebra perspective, the rings are naturally associated to a finite number of points, one point for each universe in the decomposition. Each universe is canonically associated to a representation, which defines a projector, an idempotent in the ring of dimension-zero operators. We discuss how bulk Wilson lines act as defects bridging universes, and how Wilson lines on boundaries of two-dimensional theories decompose, and compute actions of projectors. We discuss one-form symmetries of the rings, and related properties. We also give general formulas for projection operators, which previously were computed on a case-by-case basis. Finally, we propose a characterization of noninvertible higher-form symmetries in this context in terms of representations. In that characterization, non-isomorphic universes appearing in decomposition are associated with noninvertible one-form symmetries.
description: 77 pages, LaTeX; v2: reference added; v3: typos fixed and material on bulk Wilson lines added
In der Stadt ist der Wald ein anspruchsvoller Mitbewohner
Creators: name: Wilkes-Allemann, Jerylee
name: Pfund, Jean-Laurent
name: Augustinus, Benno Andreas
name: Kleinschroth, Fritz
Publisher: name: Schweizerischer Forstverein
Year: 2024

description: Der partizipative Anlass «Urban Forestry: Herausforderungen für das Management von Ökosystemleistungen in grünen Städten» thematisierte multidisziplinäre Ansätze zur Schaffung nachhaltiger und lebenswerter Grünräume in Zeiten des Klimawandels und der inneren Verdichtung in Städten. Organisiert wurde er von der ETH Zürich und vom Schweizer Netzwerk für Urban Forestry (ArboCityNet).
Overcoming User Resistance in Location Data Sharing
Creators: name: Baumann, Dominic Beat Martin
name: Hietschold, Nadine
name: Laube, Annett
name: Pruschak, Gernot
name: Yatsenko, Olena
Publisher: name: Berner Fachhochschule, Wirtschaft
Year: 2024

description: We investigate whether and how sustainability and financial incentives encourage ethical location data sharing. Our results show that users do not share their location data for the sake of sustainability. Nevertheless, we find that financial incentives increase data sharing rates modestly. Thus, when asking for data sharing in a transparent and ethical manner, privacy concerns seem to increase and reduce actual data sharing rates.
“We embrace winter here”: Celebrating place in winter cities
Creators: Stout, Madeleine
Collins, Damian
Evans, Josh
Publisher: name: University of Alberta Library
Year: 2022

Weather is an elementary and fundamental characteristic of place. In any given place we encounter the materiality of weather, local meanings attached to weather, and practices adopted in response to living with weather. Winter cities are places defined by their weather—long, cold winters that can pose challenges to urban life. Efforts to address these challenges centre on place-making activities, such as seasonal festivals, which seek to enrich public spaces. In this paper, we examine the relationship between winter, place, and placemaking in three Canadian prairie cities. Participants sought to promote a celebratory relationship with winter by changing public attitudes, fostering unique winter experiences, and incorporating winter into their cities’ identities. This shift was encouraged by strategies and events that were “authentic” to local context and community. They did not simply reframe winter weather as positive, but recognized the season as presenting both challenges and opportunities. Enabling residents to realize opportunities is critical to being a successful winter city, and requires negotiating a set of dyads: warm/cold, indoor/outdoor, and light/dark. This paper highlights the constitutive role of weather in shaping place, while revealing the agentic ways in which communities act towards and with weather.
sj-pdf-8-hss-10.1177_15563316221104765 – Supplemental material for Association Between Limited English Language Proficiency and Disparities in Length of Stay and Discharge Disposition After Total Shoulder Arthroplasty: A Retrospective Cohort Study
Creators: name: Kunze, Kyle N.
name: Estrada, Jennifer A.
name: Apostolakos, John
name: Fu, Michael C.
name: Taylor, Samuel A.
name: Gulotta, Lawrence V.
name: Dines, David M.
name: Dines, Joshua S.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-8-hss-10.1177_15563316221104765 for Association Between Limited English Language Proficiency and Disparities in Length of Stay and Discharge Disposition After Total Shoulder Arthroplasty: A Retrospective Cohort Study by Kyle N. Kunze, Jennifer A. Estrada, John Apostolakos, Michael C. Fu, Samuel A. Taylor, Lawrence V. Gulotta, David M. Dines and Joshua S. Dines in HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary
Creators: name: Cluck, David B.
name: Ladak, Amber F.
name: Jeter, Sarah B.
name: Patel, Nimish
name: Thomas, Ian
name: Kilcrease, Christin
name: Pérez, Sarah E.
name: Chahine, Elias B.
name: Chastain, Daniel B.
name: Hester, E. Kelly
name: Poe, Jonell B.
name: Short, William R.
name: Johnson, Melissa D.
name: Murray, Milena
name: Dumond, Julie B.
name: Derrick, Caroline
name: Asiago‐Reddy, Elizabeth
name: Kufel, Wesley D.
name: Kwong, Jeffrey
name: Durham, Spencer H.
name: Bolch, Charlotte
Publisher: name: Wiley
Year: 2024

description:
Treatment options are currently limited for persons with HIV-1 (PWH) who are heavily treatment-experienced and/or have multidrug-resistant HIV-1. Three agents have been approved by the U.S. Food and Drug Administration (FDA) since 2018, representing a significant advancement for this population: ibalizumab, fostemsavir, and lenacapavir. However, there is a paucity of recommendations endorsed by national and international guidelines describing the optimal use (e.g., selection and monitoring after initiation) of these novel antiretrovirals in this population. To address this gap, a modified Delphi technique was used to develop these consensus recommendations that establish a framework for initiating and managing ibalizumab, fostemsavir, or lenacapavir in PWH who are heavily treatment-experienced and/or have multidrug-resistant HIV-1. In addition, future areas of research are also identified and discussed in the main document.
Agrarpolitik erlebbar machen
Creators: name: Schärer, Ann
Publisher: name: Berner Fachhochschule, Hochschule für Agrar-, Forst- und Lebensmittelwissenschaften HAFL
Year: 2024

description: Agrarpolitik ist komplex, ihre Mechanismen sind oft schwer zu durchschauen. Ein neues Spiel soll nun im Unterricht helfen, Zusammenhänge zu verstehen. Zu Besuch bei den Spielmacher*innen.