cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 8: of Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
Creators: name: Castro, Andrea
name: Kivilcim Ozturk
name: Pyke, Rachel
name: Xian, Su
name: Zanetti, Maurizio
name: Carter, Hannah
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Figure S8. NK, CD8+ T-cell and cytotoxicity levels of patients with mutations in HLA, related to Fig. 5. (A-B-C) Boxplots comparing MSS TCGA patients with or without HLA mutations for additional tissue types not shown in Fig. 5(B-D-F), in terms of their (A) CD8+ T-cell levels, (B) NK cell levels, and (C) cytotoxicity scores. Patients are divided by tumor type and only the tumor types with at least 5 mutated patients and that have not been reported in Fig. 5 are shown. P-values are adjusted for multiple comparisons using the Benjaminiâ Hochberg procedure. (PDF 428 kb)
Protein Supplementation May Dampen Positive Effects of Exercise on Glucose Homeostasis: A Pilot Weight Loss Intervention
Creators: name: Batsis, John A.
name: Gross, Danae C.
name: Petersen, Curtis L.
name: Cook, Summer B.
name: Spangler, Hillary B.
name: Batchek, Dakota J.
name: Lynch, David H.
Publisher: name: MDPI
Year: 2023

description: Background: The role of protein in glucose homeostasis has demonstrated conflicting results. However, little research exists on its impact following weight loss. This study examined the impact of protein supplementation on glucose homeostasis in older adults >65 years with obesity seeking to lose weight. Methods: A 12-week, nonrandomized, parallel group intervention of protein (PG) and nonprotein (NPG) arms for 28 older rural adults (body mass index (BMI) ≥ 30 kg/m2) was conducted at a community aging center. Both groups received twice weekly physical therapist-led group strength training classes. The PG consumed a whey protein supplement three times per week, post-strength training. Primary outcomes included pre/post-fasting glucose, insulin, inflammatory markers, and homeostasis model assessment of insulin resistance (HOMA-IR). Results: Mean age and baseline BMI were 72.9 ± 4.4 years and 37.6 ± 6.9 kg/m2 in the PG and 73.0 ± 6.3 and 36.6 ± 5.5 kg/m2 in the NPG, respectively. Mean weight loss was −3.45 ± 2.86 kg in the PG and −5.79 ± 3.08 kg in the NPG (p < 0.001). There was a smaller decrease in pre- vs. post-fasting glucose levels (PG: −4 mg ± 13.9 vs. NPG: −12.2 ± 25.8 mg/dL; p = 0.10), insulin (−7.92 ± 28.08 vs. −46.7 ± 60.8 pmol/L; p = 0.01), and HOMA-IR (−0.18 ± 0.64 vs. −1.08 ± 1.50; p = 0.02) in the PG compared to the NPG. Conclusions: Protein supplementation during weight loss demonstrated a smaller decrease in insulin resistance compared to the NPG, suggesting protein may potentially mitigate beneficial effects of exercise on glucose homeostasis.
Racial, ethnic, and age disparities in the association of mental health symptoms and polysubstance use among persons in HIV care
Creators: name: Flamm, Jason A.
name: Luu, Mitchell N.
name: Leibowitz, Amy S.
name: Lea, Alexandra N.
name: Davy-Mendez, Thibaut
name: Iturralde, Esti
name: Smith, Jaime Dumoit
name: Satre, Derek D.
name: Silverberg, Michael J.
name: Dilley, James
name: Sarovar, Varada
name: Levine-Hall, Tory
name: Hare, C. Bradley
Publisher: name: Public Library of Science
Year: 2023

description: We characterized polysubstance use burden and associations with mental health problems across demographic subgroups of PWH. In 2018–2020, as part of a primary care-based intervention study, PWH in care at three medical centers in Kaiser Permanente Northern California were screened for depression (PHQ-9≥10), anxiety (GAD-2≥3), and substance use (Tobacco, Alcohol, Prescription medication, and other Substance use [TAPS]≥1 per substance). We used Poisson regression to estimate prevalence ratios (PRs) comparing polysubstance use prevalence (TAPS≥1 for ≥2 substances) between PWH with positive screens for depression or anxiety vs. neither, among all PWH, and stratified by race/ethnicity and age (restricted to men), adjusting for sociodemographics, CD4, and HIV load. Screened PWH (N = 2865) included 92% men, 56% White, 19% Black, and 15% Hispanic PWH, with a median age of 55 years. Overall, polysubstance use prevalence was 26.4% (95% CI 24.9%-28.1%). PWH with depression or anxiety (n = 515) had an adjusted polysubstance use PR of 1.26 (1.09–1.46) vs. PWH with neither (n = 2350). Adjusted PRs were 1.47 (1.11–1.96), 1.07 (0.74–1.54), and 1.10 (0.85–1.41) among Black, Hispanic, and White men, respectively. Adjusted PRs did not differ by age group. Interventions should consider jointly addressing mental health and substance use problems and potential drivers, e.g. stigma or socioeconomic factors.
Rebound of COVID-19 With Nirmatrelvir-Ritonavir Antiviral Therapy
Creators: name: Brown, Elizabeth R.
name: Cohen, Myron S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: In their article, Edelstein and colleagues provide the results of an observational study of virologic response in patients who received treatment with nirmatrelvir–ritonavir (N-R) versus those who received no COVID-19 therapy. The editorialists discuss the findings and emphasize the need for further consideration of the dosage, timing, and duration of treatment to inform optimal use of N-R.
Isoscaling in central Sn+Sn collisions at 270 MeV/u
Creators: name: Lee, J. W.
name: Tsang, M. B.
name: Tsang, C. Y.
name: Wang, R.
name: Barney, J.
name: Estee, J.
name: Isobe, T.
name: Kaneko, M.
name: Kurata-Nishimura, M.
name: Lynch, W. G.
name: Murakami, T.
name: Ono, A.
name: Souza, S. R.
name: Ahn, D. S.
name: Atar, L.
name: Aumann, T.
name: Baba, H.
name: Boretzky, K.
name: Brzychczyk, J.
name: Cerizza, G.
name: Chiga, N.
name: Fukuda, N.
name: Gasparic, I.
name: Hong, B.
name: Horvat, A.
name: Ieki, K.
name: Ikeno, N.
name: Inabe, N.
name: Jhang, G.
name: Kim, Y. J.
name: Kobayashi, T.
name: Kondo, Y.
name: Lasko, P.
name: Lee, H. S.
name: Leifels, Y.
name: Łukasik, J.
name: Manfredi, J.
name: McIntosh, A. B.
name: Morfouace, P.
name: Nakamura, T.
name: Nakatsuka, N.
name: Nishimura, S.
name: Otsu, H.
name: Pawłowski, P.
name: Pelczar, K.
name: Rossi, D.
name: Sakurai, H.
name: Santamaria, C.
name: Sato, H.
name: Scheit, H.
name: Shane, R.
name: Shimizu, Y.
name: Simon, H.
name: Snoch, A.
name: Sochocka, A.
name: Sumikama, T.
name: Suzuki, H.
name: Suzuki, D.
name: Takeda, H.
name: Tangwancharoen, S.
name: Togano, Y.
name: Xiao, Z. G.
name: Yennello, S. J.
name: Zhang, Y.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Experimental information on fragment emissions is important in understanding the dynamics of nuclear collisions and in the development of transport model simulating heavy-ion collisions. The composition of complex fragments emitted in the heavy-ion collisions can be explained by statistical models, which assume that thermal equilibrium is achieved at collision energies below 100 MeV/u. Our new experimental data together with theoretical analyses for light particles from Sn+Sn collisions at 270 MeV/u, suggest that the hypothesis of thermal equilibrium breaks down for particles emitted with high transfer momentum. To inspect the system's properties in such limit, the scaling features of the yield ratios of particles from two systems, a neutron-rich system of ${}^{132}\mathrm{Sn}+{}^{124}\mathrm{Sn}$ and a nearly symmetric system of ${}^{108}\mathrm{Sn}+{}^{112}\mathrm{Sn}$, are examined in the framework of the statistical multifragmentation model and the antisymmetrized molecular dynamics model. The isoscaling from low energy particles agree with both models. However the observed breakdown of isoscaling for particles with high transverse momentum cannot be explained by the antisymmetrized molecular dynamics model.
title: Zum Andenken an Frau Dr. Näf-Züblin (29. Januar 1855-9. März 1920)
title: Vorsteherin der Zürcher Heilstätte Unterägeri seit 1885
titleType: Subtitle
title: Gewidmet von den Geschwistern und dem Komitee der Heilstätte Unterägeri
titleType: Subtitle
Creators: name: (:Unkn) Unknown
Publisher: name: Buchdruckerei E. Löpfe-Benz
Year: 1920
Subjects: subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Sankt Gallen
subject: Zürich

description: Enthält: Personalien; Predigt gehalten anlässlich der Abdankungsfeier in der Anstalt in Unterägeri, von Pfarrer Nidecker, Baar; Worte der Erinnerung gesprochen bei der Bestattungsfeier im Krematorium Zürich von G. Bosshard, Pfarrer; Gedenkworte von Prof. Dr. Haab, Präsident des Komitee der Zürcher Heilstätte, Unterägeri; Nachruf in der "Zürcher Post" von Dr. Kruker
A Proof of the Strong Converse Theorem for Gaussian Multiple Access Channels
Creators: name: Fong, Silas L.
name: Tan, Vincent Y. F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We prove the strong converse for the $N$-source Gaussian multiple access channel (MAC). In particular, we show that any rate tuple that can be supported by a sequence of codes with asymptotic average error probability less than one must lie in the Cover-Wyner capacity region. Our proof consists of the following. First, we perform an expurgation step to convert any given sequence of codes with asymptotic average error probability less than one to codes with asymptotic maximal error probability less than one. Second, we quantize the input alphabets with an appropriately chosen resolution. Upon quantization, we apply the wringing technique (by Ahlswede) on the quantized inputs to obtain further subcodes from the subcodes obtained in the expurgation step so that the resultant correlations among the symbols transmitted by the different sources vanish as the blocklength grows. Finally, we derive upper bounds on achievable sum-rates of the subcodes in terms of the type-II error of a binary hypothesis test. These upper bounds are then simplified through judicious choices of auxiliary output distributions. Our strong converse result carries over to the Gaussian interference channel under strong interference as long as the sum of the two asymptotic average error probabilities less than one.
description: Explanation of the proof is added. Typos are corrected
Public political tolerance of the far right in contemporary Western Europe
Creators: name: Bjånesøy, Lise
name: Ivarsflaten, Elisabeth
name: Berntzen, Lars Erik
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Political initiatives promoting a far-right agenda have gained significant political influence in Western European democracies. This has occurred despite apparent broad-based public rejection of Europe’s Nazi past. This is a puzzle, since there are affinities between the old and the new far right. This article addresses that puzzle. Theoretically, the article distinguishes between broad and narrow interpretations of what it means to reject Europe’s Nazi past. Empirically, it shows how a well-established survey experimental template reveals substantive variations in public political tolerance of the far right. For citizens in five key Western European democracies, rejecting the Nazi past only means rejecting initiatives explicitly identified as neo-Nazi. For other far-right initiatives, political tolerance is more common and increases in accordance with these initiatives’ institutionalisation in the party system. For far-right parties fully institutionalised in the party system, public political tolerance is at the same level as for other political parties.
title: Managing the economic dimensions of peace processes: resource wealth, autonomy, and peace in Aceh
Creators: name: Wennmann, Achim
name: Krause, Jana
Publisher: name: Graduate Institute of International and Development Studies
publisherIdentifier: https://ror.org/007ygn379
publisherIdentifierScheme: ROR
Year: 2009

description: CCDP Working Paper ; no. 3
Role and effectiveness of telephone hotlines in outbreak response in Africa: A systematic review and meta-analysis
Creators: name: Rohan, Hana
name: Nchafack, Almighty
name: Fongwen, Noah T.
name: Beckmann, Nadine
name: Ong, Jason J.
name: Peeling, Rosanna W.
name: Tucker, Joseph D.
name: Hughes, Gwenda
Publisher: name: Public Library of Science
Year: 2023

description: Background In Africa, little is known about the role of telephone hotlines in outbreak response. We systematically reviewed the role and effectiveness of hotlines on outbreak response in Africa. Method We used the Cochrane handbook and searched five databases. The protocol was registered on PROSPERO (CRD42021247141). Medline, Embase, PsycINFO, Global Health and Web of Science were searched from 30 June 2020 to August 2020 for studies on the use of telephone hotlines in outbreak response in Africa published between January 1995 and August 2020. The search was also repeated on 16 September 2022. Data on effectiveness (alerts generated, cases confirmed) were extracted from peer-reviewed studies. Meta-analysis of alerts generated, and proportion of cases confirmed was done using the random effects model. The quality of studies was assessed using the Joanna Briggs Institute (JBI) tools. The heterogeneity and publication bias were assessed using the Galbraith and funnel plots, respectively. Results Our search yielded 1251 non-duplicate citations that were assessed. 41 full texts were identified, and 21 studies were included in the narrative synthesis, while 12 were included in the meta-analysis. The hotlines were local (seven studies) or national (three studies). A combination of a local and national hotline was used in one study. The hotlines were set up for unusual respiratory events (one study), polio (one study), Ebola (10 studies), COVID-19 (two studies), malaria (one study), influenza-like illnesses (ILI) (one study) and rift valley fever in livestock (one study). Hotlines were mainly used for outbreak surveillance at the local level. A total of 332,323 alerts were generated, and 67,658 met the case definition, corresponding to an overall pooled proportion of alerts generated(sensitivity) of 38% (95%CI: 24–52%). The sensitivity was 41% (95% CI: 24–59%) for local hotlines and 26%(95%CI:5–47%) for national hotlines. Hotlines were also used for surveillance of rift valley fever in livestock (one study) vaccination promotion (one study), death reporting (five studies), rumour tracking and fighting misinformation (two studies) and community engagement (five studies). The studies were of low to moderate quality with high publication bias and heterogeneity(I2 = 99%). The heterogeneity was not explained by the sample size. Conclusion These data suggest that telephone hotlines can be effective in outbreak disease surveillance in Africa. Further implementation research is needed to scale up telephone hotlines in rural areas.
Additional file 1 of Radiomic detection of microscopic tumorous lesions in small animal liver SPECT imaging
Creators: name: Veres, Dániel
name: Domokos Máthé
name: Hegedűs, Nikolett
name: Horváth, Ildikó
name: Kiss, Fanni
name: Taba, Gabriella
name: Tóth-Bodrogi, Edit
name: Kovács, Tibor
name: Szigeti, Krisztián
Publisher: name: Figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: The supplementary file contains the MATLAB script for calculating the parameters, additional example projections in each animal of the segmented liver and the values of the calculated parameters. (DOCX 1151 kb)
Global monopoles can change Universe's topology
Creators: name: Marunovic, Anja
name: Prokopec, Tomislav
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: If the Universe undergoes a phase transition, at which global monopoles are created or destroyed, topology of its spatial sections can change. More specifically, by making use of Myers' theorem, we show that, after a transition in which global monopoles form, spatial sections of a spatially flat Universe become finite and closed. This implies that global monopoles can change topology of Universe's spatial sections (from infinite and open to finite and closed). We emphasize that global monopoles cannot alter topology of the space-time manifold.
description: 5 pages, 1 figure; introduction changed; matches published version
A Machine Learning-based Framework for Predictive Maintenance of Semiconductor Laser for Optical Communication
Creators: name: Abdelli, Khouloud
name: Griesser, Helmut
name: Pachnicke, Stephan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Semiconductor lasers, one of the key components for optical communication systems, have been rapidly evolving to meet the requirements of next generation optical networks with respect to high speed, low power consumption, small form factor etc. However, these demands have brought severe challenges to the semiconductor laser reliability. Therefore, a great deal of attention has been devoted to improving it and thereby ensuring reliable transmission. In this paper, a predictive maintenance framework using machine learning techniques is proposed for real-time heath monitoring and prognosis of semiconductor laser and thus enhancing its reliability. The proposed approach is composed of three stages: i) real-time performance degradation prediction, ii) degradation detection, and iii) remaining useful life (RUL) prediction. First of all, an attention based gated recurrent unit (GRU) model is adopted for real-time prediction of performance degradation. Then, a convolutional autoencoder is used to detect the degradation or abnormal behavior of a laser, given the predicted degradation performance values. Once an abnormal state is detected, a RUL prediction model based on attention-based deep learning is utilized. Afterwards, the estimated RUL is input for decision making and maintenance planning. The proposed framework is validated using experimental data derived from accelerated aging tests conducted for semiconductor tunable lasers. The proposed approach achieves a very good degradation performance prediction capability with a small root mean square error (RMSE) of 0.01, a good anomaly detection accuracy of 94.24% and a better RUL estimation capability compared to the existing ML-based laser RUL prediction models.
description: Published in Journal of Lightwave Technology (Volume: 40, Issue: 14, 15 July 2022)
Seelsorge als Dienst an der Befreiung
Creators: name: Ladenhauf, Karl Heinz
name: Schulz, Heinz-Manfred
name: Rechberger, Walter H.
name: Erharter, Helmut
name: Mette, Norbert
name: Strolz, Walter
name: Sommer, Christine
name: Landman, Henk
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 18 Nr. 3 (1987): Diakonia, Band 18, Heft 3
First-principles calculations of indirect Auger recombination in nitride semiconductors
Creators: name: Kioupakis, Emmanouil
name: Steiauf, Daniel
name: Rinke, Patrick
name: Delaney, Kris T.
name: Van de Walle, Chris G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Auger recombination is an important non-radiative carrier recombination mechanism in many classes of optoelectronic devices. The microscopic Auger processes can be either direct or indirect, mediated by an additional scattering mechanism such as the electron-phonon interaction. Phonon-assisted Auger recombination is particularly strong in nitride materials and affects the efficiency of nitride optoelectronic devices at high powers. Here we present a first-principles computational formalism for the study of direct and indirect Auger recombination in direct-band-gap semiconductors and apply it to the case of nitride materials. We show that direct Auger recombination is weak in the nitrides and cannot account for experimental measurements. On the other hand, carrier scattering by phonons and alloy disorder enables indirect Auger processes that can explain the observed loss in devices. We analyze the dominant phonon contributions to the Auger recom- bination rate and the influence of temperature and strain on the values of the Auger coefficients. Auger processes assisted by charged-defect scattering are much weaker than the phonon-assisted ones for realistic defect densities and not important for the device performance. The computational formalism is general and can be applied to the calculation of the Auger coefficient in other classes of optoelectronic materials.
Social isolation increases from adolescence through later life but varies by gender, age, and partnership status
Creators: name: Umberson, Debra
name: Lin, Zhiyong
name: Cha, Hyungmin
Publisher: name: University of Texas at Austin Population Research Center
Year: 2022
Subjects: social isolation
negative health impacts

description: Substantial evidence has found that people who are socially isolated experience worse mental and physical health and are more likely to die compared to their less isolated peers. And while the negative health impacts of social isolation affect both men and women, social isolation unfolds over the life course and perhaps in different ways for men and women. In this research brief, CAPS director and PRC faculty scholar Debra Umberson, along with PRC faculty affiliate Zhiyong Lin, and CAPS/PRC graduate student trainee Hyungmin Cha, report on a recent study that explores the gendered patterns of social isolation from adolescence to old age. Using Add Health and Health and Retirement Study data, they find that social isolation increases from adolescence through later life and that men are more socially isolated than women across all age and partnership categories with one exception: after age 62, married women are more socially isolated than married men.
description: Substantial evidence has found that people who are socially isolated experience worse mental and physical health and are more likely to die compared to their less isolated peers. And while the negative health impacts of social isolation affect both men and women, social isolation unfolds over the life course and perhaps in different ways for men and women. In this research brief, CAPS director and PRC faculty scholar Debra Umberson, along with PRC faculty affiliate Zhiyong Lin, and CAPS/PRC graduate student trainee Hyungmin Cha, report on a recent study that explores the gendered patterns of social isolation from adolescence to old age. Using Add Health and Health and Retirement Study data, they find that social isolation increases from adolescence through later life and that men are more socially isolated than women across all age and partnership categories with one exception: after age 62, married women are more socially isolated than married men.
Additional Information
Creators: name: Godinez Garcia, Maria de Montserrat
name: Soto, Adrian
name: Catrip, Jorge
name: Gaitan, Ruben
name: Falcon, Miguel Angel
name: Aranda Fraustro, Alberto
name: Tena, Carlos Alberto
name: Zamudio, Pedro
name: Alvarez Alvarez, Rolando Joel
name: Guillen Dolores, Yazmin
name: Lespron, Ma Carmen
name: Briseño, Ivan
name: Molina, Francisco Javier
Publisher: name: figshare
Year: 2022
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: Supplementary information includes study design and flow, gastric impedance device, tables and plots with blood gas data, vital signs hemodynamics, laboratories, histology, and mucosal classification.
Degradation Prediction of Semiconductor Lasers using Conditional Variational Autoencoder
Creators: name: Abdelli, Khouloud
name: Griesser, Helmut
name: Neumeyr, Christian
name: Hohenleitner, Robert
name: Pachnicke, Stephan
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Semiconductor lasers have been rapidly evolving to meet the demands of next-generation optical networks. This imposes much more stringent requirements on the laser reliability, which are dominated by degradation mechanisms (e.g., sudden degradation) limiting the semiconductor laser lifetime. Physics-based approaches are often used to characterize the degradation behavior analytically, yet explicit domain knowledge and accurate mathematical models are required. Building such models can be very challenging due to a lack of a full understanding of the complex physical processes inducing the degradation under various operating conditions. To overcome the aforementioned limitations, we propose a new data-driven approach, extracting useful insights from the operational monitored data to predict the degradation trend without requiring any specific knowledge or using any physical model. The proposed approach is based on an unsupervised technique, a conditional variational autoencoder, and validated using vertical-cavity surface-emitting laser (VCSEL) and tunable edge emitting laser reliability data. The experimental results confirm that our model (i) achieves a good degradation prediction and generalization performance by yielding an F1 score of 95.3%, (ii) outperforms several baseline ML based anomaly detection techniques, and (iii) helps to shorten the aging tests by early predicting the failed devices before the end of the test and thereby saving costs
description: Published in: Journal of Lightwave Technology (Volume: 40, Issue: 18, 15 September 2022)
Opinions Towards the Use of Reciprocal Teaching Strategy in English Reading of Thai Lower Secondary Level Students
Creators: name: Apisara Kaewsuan
Publisher: name: Faculty of Liberal Arts, Prince of Songkla University
Year: 2023
Subjects: opinionson the use of RTS
reciprocal teaching strategy
English reading
lower secondary school students

description: Journal of Liberal Arts, Prince of Songkla University, 15, 2, 267957, pp. 1-18
Safety and Efficacy of Concurrent Atezolizumab/Bevacizumab or Nivolumab Combination Therapy with Yttrium-90 Radioembolization of Advanced Unresectable Hepatocellular Carcinoma
Creators: name: Kokabi, Nima
name: Dabbous, Howard Hussein
name: Gbolahan, Olumide Babajide
name: Little, Olivia
name: Villalobos, Alexander
name: Lilly, Meghan Allegra
name: Akce, Mehmet
name: Bercu, Zachary
Publisher: name: MDPI
Year: 2023

description: To evaluate the safety and efficacy of combining yttrium-90 radioembolization (Y90-RE) with immune checkpoint inhibitor therapy, consecutive advanced unresectable hepatocellular carcinoma (HCC) patients treated between 2016 and 2022 with atezolizumab/bevacizumab or nivolumab within three-months pre- and post-Y90-RE were retrospectively evaluated. Tumor response and treatment-related clinical/laboratory adverse events (AE) were assessed at 1 and 6 months, as well as differences in clinical and laboratory variables and median overall survival (OS) from initial treatment (whether it was Y90-RE or systemic therapy) between the two cohorts. A total of 19 patients (10 atezolizumab/bevacizumab; 9 nivolumab), comprising 84% males with median age 69 years, met the inclusion criteria. Compared to the atezolizumab/bevacizumab group, there were less males (100% vs. 67%; p = 0.02) and more ECOG ≥ 2 patients in the nivolumab group (0% vs. 33%; p = 0.02). Baseline characteristics or incidence of 6-month post-treatment any-grade AE (60% vs. 56%; p = 0.7), grade ≥ 3 AE (0% vs. 11%; p = 0.3), objective response (58% total, 60% vs. 56%; p = 0.7), and complete response (16% total; 10% vs. 22%; p = 0.8) were similar between the atezolizumab/bevacizumab and the nivolumab cohorts. Median OS was 12.9 months for the whole cohort, 16.4 months for nivolumab, and 10.7 months for atezolizumab/bevacizumab. Among patients with advanced unresectable HCC, the utilization of Y90-RE concurrently or within 90 days of nivolumab or atezolizumab/bevacizumab immunotherapy, appears to be well-tolerated and with a low incidence of severe AE.
Additional file 4: of Interventions to promote patients and familiesâ involvement in adult intensive care settings: a protocol for a mixed-method systematic review
Creators: name: Xyrichis, Andreas
name: Fletcher, Simon
name: Brearley, Sally
name: Philippou, Julia
name: Purssell, Ed
name: Terblanche, Marius
name: Rafferty, Anne
name: Reeves, Scott
Publisher: name: Figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Draftâ quantitative quality assessment form. (DOCX 19 kb)
Predicting short term outcomes of infants receiving Ponseti management for idiopathic clubfoot
Creators: name: Quinlan, Rachal
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: This thesis explores a different way of using the most common clubfoot scoring system, the Pirani scale, to provide prognostic information. Currently, predicting treatment outcomes using total Pirani scale scores at initial assessment has varied results. Anecdotally, different patterns of midfoot and hindfoot correction in idiopathic clubfoot during Ponseti management have been noted in the clubfoot clinic at a paediatric tertiary institution. However, the prognostic value of change in Pirani scale midfoot (MFS) and hindfoot (HFS) components during Ponseti management has not been robustly investigated. Therefore, a retrospective study reviewing medical records of 226 children with 335 idiopathic clubfoot from 2008-2020 was completed. Group-based trajectory of MFS and HFS identified four subgroups of clubfoot that followed statistically distinct patterns of change during Ponseti management. Tenotomy rate differed between the subgroups demonstrating the role of subgrouping to predict outcomes in Ponseti managed idiopathic clubfoot. This is the first report of the existence of four subgroups of idiopathic clubfoot and their ability to predict some short term treatment outcomes. Future research should focus on prospectively evaluating the existence of these subgroups in other idiopathic clubfoot cohorts and the ability of the subgroups to predict long term treatment outcomes.
Low red-shift effects of local structure on the Hubble parameter in presence of a cosmological constant
Creators: name: Romano, Antonio Enea
name: Vallejo, Sergio Andres
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In order to estimate the effects of local structure on the Hubble parameter we calculate the low-redshift expansion for $H(z)$ and $\frac{δH}{H}$ for an observer at the center of a spherically symmetric matter distribution in presence of a cosmological constant. We then test the accuracy of the formulae comparing them with fully relativistic non perturbative numerical calculations for different cases for the density profile. The low red-shift expansion we obtain gives results more precise than perturbation theory since is based on the use of an exact solution of Einstein's field equations. For larger density contrasts the low red-shift formulae accuracy improves respect to the perturbation theory accuracy because the latter is based on the assumption of a small density contrast, while the former does not rely on such assumption. The formulae can be used to take into account the effects on the Hubble expansion parameter due to the monopole component of the local structure. If the $H(z)$ observations will show deviations from the $ΛCDM$ prediction compatible with the formulae we have derived, this could be considered an independent evidence of the existence of a local inhomogeneity, and the formulae could be used to determine the characteristics of this local structure.
description: 14 pages, 4 figures
Ideational agenda-setting leadership: President von der Leyen and the EU response to the invasion of Ukraine
Creators: name: Baracani, Elena
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: This article presents an ideational perspective on agenda-setting leadership, which it applies to the role played by President von der Leyen in the EU’s response to the crisis that followed the Russian full-scale military invasion of Ukraine that started on 24 February 2022. On a conceptual and methodological level, by searching for evidence of strategic framing, this study traces the process of President von der Leyen’s ideational agenda-setting leadership and how it influenced the overall development of the EU’s response during the initial ten weeks of the crisis. The empirical findings contribute to the academic debate on the Commission President’s leadership in a crisis context by revealing how her principled ideas enabled her to diagnose the situation precisely and devise clear priorities and tools to address it. The empirical analysis also suggests that President von der Leyen, in line with her geopolitical Commission, played a very active foreign policy role.
Additional file 1 of Multidrug-resistant enterobacteriaceae in coastal water: an emerging threat
Creators: name: Cohen, Regev
name: Paikin, Svetlana
name: Rokney, Assaf
name: Rubin-Blum, Maxim
name: Peleg Astrahan
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Figure 1: Alignment of IMI type carbapenem-hydrolyzing class A beta-lactamase amino acid sequences (see Figure 2 in the main text for accession numbers). Names of novel IMI alleles are marked in blue, cysteine to phenylalanine substitution is shown in the frame.
Sex Differences in Mouse Cardiac Electrophysiology Revealed by Simultaneous Imaging of Excitation-Contraction Coupling
Creators: name: Shi, Wei
name: Conlon, Frank L.
name: Ariel, Pablo
name: Emerson, James I.
Publisher: name: MDPI
Year: 2023

description: Males and females differ in the basic anatomy and physiology of the heart. Sex differences are evident in cardiac repolarization in humans; women have longer corrected QT and JT intervals. However, the molecular mechanisms that lead to these differences are incompletely understood. Here, we present that, like in humans, sex differences in QT and JT intervals exist in mouse models; female mice had longer corrected QT and JT intervals compared with age-matched males. To further understand the molecular underpinning of these sex differences, we developed a novel technology using fluorescent confocal microscopy that allows the simultaneous visualization of action potential, Ca2+ transients, and contractions in isolated cardiomyocytes at a high temporal resolution. From this approach, we uncovered that females at baseline have increased action potential duration, decreased Ca2+ release and reuptake rates, and decreased contraction and relaxation velocities compared with males. Additionally, males had a shorter overall time from action potential onset to peak contraction. In aggregate, our studies uncovered male and female differences in excitation-contraction coupling that account for differences observed in the EKG. Overall, a better understanding of sex differences in electrophysiology is essential for equitably treating cardiac disease.
Dynamical Mean-Field Theory description of the voltage induced transition in a non-equilibrium superconductor
Creators: name: Amaricci, A.
name: Capone, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Using dynamical mean-field theory (DMFT) we study a simplified model for heterostructures involving superconductors. The system is driven out-of-equilibrium by a voltage bias, imposed as an imbalance of chemical potential at the interface. We solve the self-consistent DMFT equations using iterative second-order perturbation theory in the Nambu-Keldysh formalism. We show that the superconducting state is destabilized by voltage biases of the order of the energy gap. We demonstrate that the transition to the normal state occurs through an intermediate bad superconducting state, which is characterized by a smaller value of the order parameter and incoherent excitations. We discuss the energetic balance behind the stabilization of such exotic superconducting state.
description: 6 pages, 3 figures
Intergenerational Racial Justice for the Korean American Community
Creators: name: Jung, Sarah
Publisher: name: Stanford Digital Repository
Year: 2022
Subjects: Korean American racial justice
Korean American intergenerational relationships
Korean American interracial relationships

description: This paper discusses an ongoing community-based research project with the HANA Center, a community organization for Korean Americans in the greater Chicagoland area, conducted in the summer of 2022. The primary aim of the research project is to build consciousness, awareness, and engagement with racial justice issues within the Korean American community through conversations and listening sessions, promoting healthy engagement and discussion of topics such as personal experiences with racism, Korean American perceptions of other communities of color, and what needs to be improved across both intergenerational and interracial lines in order to work towards racial justice.
Multi-level blame attribution and public support for EU welfare policies
Creators: name: Baute, Sharon
name: Pellegata, Alessandro
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Since the Eurozone crisis, intense political debate has resurfaced about deservingness judgements in European solidarity. To contribute to this debate, this article proposes a refined concept of ‘multi-level blame attribution’. It postulates that public support for EU-level welfare policies crucially depends on how citizens attribute responsibility for economic outcomes across different levels of agency. Results from an original public opinion survey conducted in 10 European Union member states demonstrate that attributing blame to individuals decreases citizens’ willingness to show solidarity with needy Europeans, whereas attributing blame to the EU increases support. The role of attributing blame to national governments is dependent on the country context; beliefs that worse economic outcomes are caused by national governments’ policy decisions tend to dampen support for EU targeted welfare policies only in the Nordic welfare states. The article concludes by discussing the implications of multi-level blame attribution for the formation of public attitudes towards European solidarity.
Isomorphism classes for higher order tangent bundles
Creators: name: Suri, Ali
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: Primary 58B20, Secondary 58A05

description: The tangent bundle $T^kM$ of order $k$, of a smooth Banach manifold $M$ consists of all equivalent classes of curves that agree up to their accelerations of order $k$. In the previous work of the author he proved that $T^kM$, $1\leq k\leq \infty$, admits a vector bundle structure on $M$ if and only if $M $ is endowed with a linear connection or equivalently a connection map on $T^kM$ is defined. This bundle structure depends heavily on the choice of the connection. In this paper we ask about the extent to which this vector bundle structure remains isomorphic. To this end we define the notion of the $k$'th order differential $T^kg:T^kM\longrightarrow T^kN$ for a given differentiable map $g$ between manifolds $M$ and $N$. As we shall see, $T^kg$ becomes a vector bundle morphism if the base manifolds are endowed with $g$-related connections. In particular, replacing a connection with a $g$-related one, where $g:M\longrightarrow M$ is a diffeomorphism, follows invariant vector bundle structures. Finally, using immersions on Hilbert manifolds, convex combination of connection maps and manifold of $C^r$ maps we offer three examples to support our theory and reveal its interaction with the known problems such as Sasaki lift of metrics.
description: 21 pages
MOESM1 of Transgene stacking in potato using the GAANTRY system
Creators: name: McCue, Kent
name: Gardner, Ethan
name: Chan, Ronald
name: Thilmony, Roger
name: Thomson, James
Publisher: name: Figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Plant Biology

description: Additional file 1: Fig. S1. Transgene copy number measurements in seven potato 10-stack events.
Simulations suggest walking with reduced propulsive force would not mitigate the energetic consequences of lower tendon stiffness
Creators: name: Franz J.R.
name: Sawicki G.S.
name: Pimentel R.E.
Publisher: name: Public Library of Science
Year: 2023

description: Aging elicits numerous effects that impact both musculoskeletal structure and walking function. Tendon stiffness (kT) and push-off propulsive force (FP) both impact the metabolic cost of walking and are diminished by age, yet their interaction has not been studied. We combined experimental and computational approaches to investigate whether age-related changes in function (adopting smaller FP) may be adopted to mitigate the metabolic consequences arising from changes in structure (reduced kT). We recruited 12 young adults and asked them to walk on a force-sensing treadmill while prompting them to change FP (±20% & ±40% of typical) using targeted biofeedback. In models driven by experimental data from each of those conditions, we altered the kT of personalized musculoskeletal models across a physiological range (2–8% strain) and simulated individual-muscle metabolic costs for each kT and FP combination. We found that kT and FP independently affect walking metabolic cost, increasing with higher kT or as participants deviated from their typical FP. Our results show no evidence for an interaction between kT and FP in younger adults walking at fixed speeds. We also reveal complex individual muscle responses to the kT and FP landscape. For example, although total metabolic cost increased by 5% on average with combined reductions in kT and FP, the triceps surae muscles experienced a 7% local cost reduction on average. Our simulations suggest that reducing FP during walking would not mitigate the metabolic consequences of lower kT. Wearable devices and rehabilitative strategies can focus on either kT or FP to reduce age-related increases in walking metabolic cost.
สถานการณ์การวิจัยด้านเภสัชวิทยา และพิษวิทยาของสลอด
Creators: name: รณชัย ภูวันนา
Publisher: name: สถาบันวิจัยและพัฒนา
Year: 2024
Subjects: องค์ประกอบทางเคมี
ความเป็นพิษ
สลอด

description: วารสารวิทยาศาสตร์ เทคโนโลยี และนวัตกรรม มหาวิทยาลัยกาฬสินธุ์, 3, 2, 14-24
Bipolar region formation in stratified two-layer turbulence
Creators: name: Warnecke, Jörn
name: Losada, Illa R.
name: Brandenburg, Axel
name: Kleeorin, Nathan
name: Rogachevskii, Igor
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: This work presents an extensive study of the previously discovered formation of bipolar flux concentrations in a two-layer model. We interpret the formation process in terms of negative effective magnetic pressure instability (NEMPI), which is a possible mechanism to explain the origin of sunspots. In our simulations, we use a Cartesian domain of isothermal stratified gas that is divided into two layers. In the lower layer, turbulence is forced with transverse nonhelical random waves, whereas in the upper layer no flow is induced. A weak uniform magnetic field is imposed in the entire domain at all times. In this study we vary the stratification by changing the gravitational acceleration, magnetic Reynolds number, strength of the imposed magnetic field, and size of the domain to investigate their influence on the formation process. Bipolar magnetic structure formation takes place over a large range of parameters. The magnetic structures become more intense for higher stratification until the density contrast becomes around $100$ across the turbulent layer. For the Reynolds numbers considered, magnetic flux concentrations are generated at magnetic Prandtl number between 0.1 and 1. The magnetic field in bipolar regions increases with higher imposed field strength until the field becomes comparable to the equipartition field strength of the turbulence. A larger horizontal extent enables the flux concentrations to become stronger and more coherent. The size of the bipolar structures turns out to be independent of the domain size. In the case of bipolar region formation, we find an exponential growth of the large-scale magnetic field, which is indicative of a hydromagnetic instability. Additionally, the flux concentrations are correlated with strong large-scale downward and converging flows. These findings imply that NEMPI is responsible for magnetic flux concentrations.
description: 15 pages, 13 figures, Astronomy and Astrophysics, published