Increased prevalence of non-communicable physical health conditions among autistic adults
Creators: name: Weir, Elizabeth
name: Allison, Carrie
name: Warrier, Varun
name: Baron-Cohen, Simon
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Autism and Physical Health Across the Lifespan
adults
autism spectrum disorders
health services
medical comorbidity

description: Funder: National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care East of England at Cambridgeshire and Peterborough NHS Foundation Trust
description: Funder: NIHR Biomedical Research Centre, Cambridge
description: Funder: The Rosetrees Trust
description: Funder: Corbin Charitable Trust
description: Funder: Templeton World Charity Foundation; FundRef: https://doi.org/10.13039/501100011730
description: Funder: Wellcome Trust; FundRef: https://doi.org/10.13039/100004440
description: Funder: Cambridgeshire and Peterborough NHS Foundation Trust
description: Funder: Medical Research Council; FundRef: https://doi.org/10.13039/501100000265
description: Funder: Autism Research Trust
description: Funder: university of cambridge; FundRef: https://doi.org/10.13039/501100000735
description: Autistic individuals may be at risk of premature mortality, and physical health comorbidity increases this risk; however, most studies fail to include older autistic adults or consider lifestyle-related factors that affect health. We developed an anonymous, online physical health survey. The final sample included n = 2368 individuals (mean age = 41.42), and of these, n = 1156 were autistic individuals (mean age = 40.98). We utilized three sex-stratified statistical models to determine the prevalence of cancer, cardiovascular conditions, respiratory conditions, and diabetes. All three models indicate that autistic females are more likely to have cardiovascular conditions, respiratory conditions, asthma, low blood pressure, arrhythmias, and prediabetes than non-autistic females, and autistic males are more likely to have arrhythmias than non-autistic males; these results suggest that autistic individuals carry increased risks for these conditions when compared to the general population, even after controlling for age, ethnicity, education level, body mass index, smoking, and alcohol use. Further, these risks may differ depending on biological sex for autistic individuals. Autistic adults, and particularly autistic females, have greater and wider-ranging risks than previously thought, even after controlling for demographic and lifestyle-related factors. Although this is a large sample of autistic adults across the lifespan, future research should employ larger, population-based samples to confirm these findings. Lay abstract: Previous research indicates autistic individuals die at a younger age than others and that this is possibly due in part to chronic physical health conditions. The present study used an anonymous, online survey to determine how common certain physical health conditions are among autistic adults, compared with non-autistic adults. We found autistic adults are more likely to develop heart conditions, lung conditions, and diabetes than non-autistic adults. Autistic females may be at higher risk of developing certain conditions (including respiratory conditions, asthma, and prediabetes) than autistic males. Finally, autistic individuals have increased health risks even when considering lifestyle factors (such as smoking, alcohol, and body mass index). This is still a relatively small study, and future research needs to confirm these findings and identify why these risks exist.