cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Assignment of a dubious gene cluster to melanin biosynthesis in the tomato fungal pathogen Cladosporium fulvum
Creators: name: Griffiths, Scott A.
name: Cox, Russell J.
name: Overdijk, Elysa J. R.
name: Mesarich, Carl H.
name: Saccomanno, Benedetta
name: Lazarus, Colin M.
name: De Wit, Pierre J. G. M.
name: Collemare, Jerome
Publisher: name: San Francisco : Public Library of Science
Year: 2018
Subjects: subject: pathogenic fungi
subject: gene cluster
subject: mutants
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: Pigments and phytotoxins are crucial for the survival and spread of plant pathogenic fungi. The genome of the tomato biotrophic fungal pathogen Cladosporium fulvum contains a predicted gene cluster (CfPKS1, CfPRF1, CfRDT1 and CfTSF1) that is syntenic with the characterized elsinochrome toxin gene cluster in the citrus pathogen Elsinoe fawcettii. However, a previous phylogenetic analysis suggested that CfPks1 might instead be involved in pigment production. Here, we report the characterization of the CfPKS1 gene cluster to resolve this ambiguity. Activation of the regulator CfTSF1 specifically induced the expression of CfPKS1 and CfRDT1, but not of CfPRF1. These co-regulated genes that define the CfPKS1 gene cluster are orthologous to genes involved in 1,3-dihydroxynaphthalene (DHN) melanin biosynthesis in other fungi. Heterologous expression of CfPKS1 in Aspergillus oryzae yielded 1,3,6,8-tetrahydroxynaphthalene, a typical precursor of DHN melanin. Delta cfpks1 deletion mutants showed similar altered pigmentation to wild type treated with DHN melanin inhibitors. These mutants remained virulent on tomato, showing this gene cluster is not involved in pathogenicity. Altogether, our results showed that the CfPKS1 gene cluster is involved in the production of DHN melanin and suggests that elsinochrome production in E. fawcettii likely involves another gene cluster.
Gravitational and harmonic oscillator potentials on surfaces of revolution
Creators: name: Santoprete, Manuele
Publisher: name: arXiv
Year: 2013
Subjects: subject: Dynamical Systems (math.DS)
subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In this paper, we consider the motion of a particle on a surface of revolution under the influence of a central force field. We prove that there are at most two analytic central potentials for which all the bounded, nonsingular orbits are closed and that there are exactly two on some surfaces with constant Gaussian curvature. The two potentials leading to closed orbits are suitable generalizations of the gravitational and harmonic oscillator potential. We also show that there could be surfaces admitting only one potential that leads to closed orbits. In this case, the potential is a generalized harmonic oscillator. In the special case of surfaces of revolution with constant Gaussian curvature, we prove a generalization of the well-known Bertrand theorem.
description: 23 pages
title: М. И. Тубянский. Некоторые проблемы монгольской литературы дореволюционного периода. Предисловие, под¬готовка переиздания, примечания, приложение Т. В. Ермаковой и Е. П. Островской // MONGOLICA. Caнкт-Петербургский журнал монголоведных исследований, Том XXII, 2019, №1
Creators: name: Ермакова, Татьяна Викторовна
name: Островская, Елена Петровна
Publisher: name: Издательство "Петербургское востоковедение"
Year: 2019

description: Публикация представляет собой переиздание одной из лучших монголоведческих работ ученого-востоковеда широкого профиля Михаила Израилевича Тубянского (1893–1937), чья научная деятельность с 1927 по 1936 г. протекала в МНР. В этой работе сформулированы методологические вопросы развития монгольского литературоведения, проанализирован состав дореволюционного литературного наследия и дана его классификация, впервые выстроенная в соответствии с системой монгольской культуры. М. И. Тубянский показал, что в феодальный период монгольскими авторами была создана крупная литература на тибетском языке, занимавшая положение национальной литературной традиции и пользовавшаяся известностью в Центральной Азии. Работа была написана в качестве критического отклика на статью члена-корреспондента АН СССР Н. Н. Поппе «Задачи и перспективы исследования монгольского языка и литературы», опубликованную в третьем номере журнала «Современная Монголия» за 1935 г., и вышла в свет в том же журнале с пометкой от редакции: «Печатается в дискуссионном порядке». В дальнейшем она неоднократно характеризовалась авторитетными филологами-монголистами как обладающая значительной научной ценностью, но по политическим причинам оказалась на многие десятилетия фактически выведенной из научного оборота. Настоящая публикация подготовлена по изданию: Тубянский М. И. Некоторые проблемы монгольской литературы дореволюционного периода // Современная Монголия. 1935. № 5 (12). С. 7–31.
Epilobium parviflorum
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: E. paIustre X parviflorum Cat. 145. Keine neuen Fundorte bekanntgeworden.
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
title: Круглый стол «Монголоведение в Санкт-Петербурге: ретроспектива и современность» // MONGOLICA. Caнкт-Петербургский журнал монголоведных исследований, Том XXII, 2019, №1
Creators: name: Кульганек, Ирина Владимировна
Publisher: name: Издательство "Петербургское востоковедение"
Year: 2019

description: Публикация является обзором круглого стола по проблемам отечественного монголоведения, проходившего в Санкт-Петербурге 10 июня 2019 года.
title: Юбилей историка и востоковеда Александра Ивановича Андреева // MONGOLICA. Caнкт-Петербургский журнал монголоведных исследований, Том XXII, 2019, №1
Creators: name: Юсупова, Татьяна Ивановна
Publisher: name: Издательство "Петербургское востоковедение"
Year: 2019

description: Материал представляет собой краткую заметку о научной деятельности петербургского историка науки Александра Ивановича Андреева.
LCAAJ audio for location 47197 (Vác, Hungary)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Vác, Hungary (47.78418, 19.135178)
title: Ernst Baltrusch, Die Juden und das Römische Reich
Creators: name: Engels, David
Publisher: name: University Library Heidelberg
Year: 2016

description: Rezension zu: Ernst Baltrusch, Die Juden und das Römische Reich. Geschichte einer konfliktreichen Beziehung. Wissenschaftliche Buchgesellschaft, Darmstadt 2002. 223 Seite
Insertion of Nanoluc into the Extracellular Loops as a Complementary Method To Establish BRET-Based Binding Assays for GPCRs
Creators: name: Grätz, Lukas
name: Müller, Christoph
name: Pegoli, Andrea
name: Schindler, Lisa
name: Bernhardt, Günther
name: Littmann, Timo
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: G protein-coupled receptor bioluminescence resonance energy transfer ligand binding assay development binding kinetics
subject: 570 Biowissenschaften, Biologie
subject: 540 Chemie

description: Luminescence-based techniques play an increasingly important role in all areas of biochemical research, including investigations on G protein-coupled receptors (GPCRs). One quite recent and popular addition has been made by introducing bioluminescence resonance energy transfer (BRET)-based binding assays for GPCRs, which are based on the fusion of nanoluciferase (Nluc) to the N-terminus of the receptor and the occurring energy transfer via BRET to a bound fluorescent ligand. However, being based on BRET, the technique is strongly dependent on the distance/orientation between the luciferase and the fluorescent ligand. Here we describe an alternative strategy to establish BRET-based binding assays for GPCRs, where the N-terminal fusion of Nluc did not result in functioning test systems with our fluorescent ligands (e.g., for the neuropeptide Y Y1 receptor (Y1R) and the neurotensin receptor type 1 (NTS1R)). Instead, we introduced Nluc into their second extracellular loop and we obtained binding data for the fluorescent ligands and reported standard ligands (in saturation and competition binding experiments, respectively) comparable to data from the literature. The strategy was transferred to the angiotensin II receptor type 1 (AT1R) and the M1 muscarinic acetylcholine receptor (M1R), which led to affinity estimates comparable to data from radioligand binding experiments. Additionally, an analysis of the binding kinetics of all fluorescent ligands at their respective target was performed using the newly described receptor/Nluc-constructs.
Effective System for Pregnant Women using Mobile GIS
Creators: name: Ismaeel, Ayad Ghany
name: Jabar, Emad Khadhm
Publisher: name: arXiv
Year: 2013
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: World Health Organization showed at one year about 287 000 women died most of them during and following pregnancy and childbirth in Africa and south Asia. This paper suggests mHealth system for serving pregnant women, that proposed system is first an effective mHealth system works base on mobile GIS to select adjacent care centre or hospital maternity on Google map at online registration for woman pregnant, that is done when the pregnant woman will send SMS via GPRS network contains her ID and coordinates (Longitude and Latitude) the server when receive it will search database support that system and using the same infrastructure for help the pregnant women at her location (home, market, etc) in emergency cases when the woman send SMS contains her coordinates for succoring. Implement the proposed pregnant women system shows more effective from view of cost than other systems because it works in economic (SMS) mode and from view of serve the system can easy and rapidly manage when achieving locally registration, succoring in emergency cases, change the review date of pregnant woman, as well as different types of advising. Keywords Pregnant Women, mHealth System, General Packet Radio Service (GPRS); Mobile GIS; Short Message Service (SMS), Global Position System (GPS).
description: 7 pages,10 Figures, 4 Tables
title: ШЕРСТНАЯ И МЯСНАЯ ПРОДУКТИВНОСТЬ ПОТОМСТВА СЕВЕРО-КАВКАЗСКОЙ МЯСОШЕРСТНОЙ ПОРОДЫ
title: THE WOOL AND MEAT PRODUCTIVITY OF THE PROGENY OF THE NORTH CAUCASUS MUTTON-WOOL BREED
Creators: name: Захарина, М.И.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: В послeднее врeмя в приоритете работы по увeличению числeнности скороспeлых мясо-шерстных пород и разработки по вывeдению новых с использованиeм отeчественных по-род овец. В статье приведены сравнительные исследования по изучению шерстной и мяс-ной продуктивности потомства.
description: Recently in a priority of work on increase in number of precocious meat-wool breeds and development on removal new with use of domestic breeds of sheep. The article presents compara-tive studies on the study of wool and meat productivity of offspring.
Relevance-shifted tests for high dimensional data with small sample sizes
Creators: name: Frömke, Cornelia
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2006
Subjects: subject: K-fold
subject: nonparametric
subject: test on ratio
subject: relevance-shifted hypothesis
subject: Dewey Decimal Classification::500 | Naturwissenschaften::510 | Mathematik

description: [no abstract]
LCAAJ audio for location 46182 (Bonyhád, Hungary)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Bonyhád, Hungary (46.298102, 18.526353)
title: Hartmut Leppin, Theodosius der Große. Auf dem Wege zum christlichen Imperium
Creators: name: Wirth, Gerhard
Publisher: name: University Library Heidelberg
Year: 2016

description: Rezension zu: Hartmut Leppin, Theodosius der Große. Auf dem Wege zum christlichen Imperium. Wiss. Buchgesellschaft, Darmstadt 2003. 280 Seiten
Role of the Rdr1 gene family in the black spot resistance in roses
Creators: name: Röhrs, Ina
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2019
Subjects: subject: Diplocarpon rosae
subject: TIR-NBS-LRR
subject: R-Gene
subject: Evolution
subject: RT-qPCR
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: Black spot disease, caused by the hemibiotrophic ascomycete Diplocarpon rosae, is the most severe disease in field-grown roses. The Rdr1 locus, comprising nine highly similar TNL-genes, was previously characterised in roses and it is known to confer resistance to black spot. To identify the active Rdr1 gene, we analysed stable transgenic roses harbouring single members of the Rdr1 locus in a disease assay. muRdr1A was identified as the functional Rdr1 and it provides resistance to 13 different single-spore isolates of Diplocarpon rosae belonging to six different races; so far, Rdr1 is only overcome by two races. The identification and phylogenetic analysis of Rdr1-family members from the two recently available genomes of the diploid old Chinese Rosa chinensis cultivar ‘Old Blush’, together with nine different rose species, resulted in a genomic organisation of the Rdr1-family in two major clusters at the distal end of chromosome 1 with different ancient origins. Genes belonging to cluster 2, like the functional muRdr1A, were subjected to a faster evolution compared to genes from cluster 1 due to known processes, such as higher rates of recombination, gene conversion, and birth and death processes. In addition, phylogenetic analysis with additional Rdr1 homologues identified in other Rosaceae, i.e. Fragaria, Malus, Prunus and Rubus, resulted in the hypothesis that the Rdr1-family moved to its current position after the split of Rubeae from other groups within Rosoideae. Transcriptomic analysis during the compatible interaction of roses and D. rosae indicated an initial PTI reaction which is either insufficient, avoided or suppressed by D. rosae. As for the incompatible interaction of roses and D. rosae caused by Rdr1, two genes (peroxidase superfamily protein and Kunitz family trypsin and protease inhibitor protein) showed significant higher expressions in the incompatible interaction compared to the compatible interaction, independently of the genetic background. In conclusion, Rdr1 can be used as the starting point for the breeding of rose varieties with a durable broad spectrum resistance against D. rosae. Furthermore, the genomic organisation and the sequence information of the Rdr1-family provided in this study is a valuable source to analyse the role of Rdr1 homologs in disease resistance in other species.
LCAAJ audio for location 47256 (Gura Humorului (Gura Humora), Romania)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Gura Humorului (Gura Humora), Romania (47.553889, 25.889167)
Modular dynamical systems on networks
Creators: name: DeVille, Lee
name: Lerman, Eugene
Publisher: name: arXiv
Year: 2013
Subjects: subject: Dynamical Systems (math.DS)
subject: Physics and Society (physics.soc-ph)
subject: Molecular Networks (q-bio.MN)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We propose a new framework for the study of continuous time dynamical systems on networks. We view such dynamical systems as collections of interacting control systems. We show that a class of maps between graphs called graph fibrations give rise to maps between dynamical systems on networks. This allows us to produce conjugacy between dynamical systems out of combinatorial data. In particular we show that surjective graph fibrations lead to synchrony subspaces in networks. The injective graph fibrations, on the other hand, give rise to surjective maps from large dynamical systems to smaller ones. One can view these surjections as a kind of "fast/slow" variable decompositions or as "abstractions" in the computer science sense of the word.
description: 37 pages. Major revision of arXiv:1008.5359 [math.DS]. Following referees' suggestions we made the paper more accessible for applied dynamicists
title: ВЛИЯНИЕ ВВОДНОГО СКРЕЩИВАНИЯ СВИНЕЙ НА КАЧЕСТВО ТУШ И ФИЗИКО ХИМИЧЕСКИЕ ПОКАЗАТЕЛИ МЯСА
title: THE INFLUENCE OF INTRODUCTORY CROSSBREEDING OF PIGS ON THE QUALITY OF CARCASSES AND PHYSICO-CHEMICAL INDICATORS OF MEAT
Creators: name: Зацаринин, А.А.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: Изучены морфологический состав и физико-химические показатели мяса свиней при вводном скрещивании свиноматок крупной белой породы с хряками породы йоркшир. Использование породы йоркшир, позволило увеличить длину туши и массу окорока у свиней крупной белой породы на 4,2 % (Р>0,99) и 12,3 % (Р>0,99) - в первом поколении, 3,4 % (Р>0,95) и 8,4 % (Р>0,95) - во втором; увеличить выход мышечной ткани и понизить содержание жира в тушах молодняка крупной белой породы: на 4,9% и 4,0 %, 3,9% и 2,8 % -  для первого и второго поколения соответственно. Использование хряков породы йоркшир при вводном скрещивании, способствует улучшению мясных качеств туш, отли-чающихся высоким выходом мышечной ткани, ее питательной ценности и вполне хоро-шими функционально-технологическим свойствам.
description: Studied the morphological structure and physico-chemical characteristics of meat of pigs in the introductory crossbreeding of sows of large white breed with boars of the Yorkshire breed. The use of the Yorkshire breed made it possible to increase carcass length and ham weight in large white pigs by 4.2 % (P>0.99) and 12.3 % (P>0.99) - in the first generation, 3.4 % (P>0.95) and 8.4 % (P>0.95) - in the second generation; to increase the yield of muscle tissue and reduce the fat content in the carcasses of young large white breeds: by 4.9% and 4.0 %, 3.9% and 2.8 % - for the first and second generation, respectively. Тhe use of Yorkshire boars in the introductory crossing, improves the meat qualities of carcasses, characterized by high yield of muscle tissue, its nutritional value and quite good functional and technological properties.
title: ТЕРАПЕВТИЧЕСКАЯ ЭФФЕКТИВНОСТЬ ТРИОЛАКТА ПРИ ЛЕЧЕНИИ СУБКЛИНИЧЕСКОГО МАСТИТА
title: THERAPEUTIC EFFICACY OF TRIOLACT IN THE TREATMENT OF SUBCLINICAL MASTITIS
Creators: name: Корчагина, А.А.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: Широкое распространение различных форм маститов остается актуальной проблемой со-временного молочного животноводства ввиду больших экономический потерь из-за преж-девременной выбраковки животных, недополучения и снижения качества продукции. При этом субклинический мастит, несмотря на отсутствие клинических проявлений заболева-ния, снижает молочную продуктивность коров на 10-15%, что приводит к потере до 700 кг молока от каждой коровы за период лактации. Для минимизации подобных негативных аспектов производства, необходимо своевременное и адекватное лечение поголовья скота с использованием современных препаратов
description: The wide distribution of various forms of mastitis remains an urgent problem of modern dairy farming due to large economic losses due to the premature culling of animals, short-receiving and reducing product quality. At the same time, subclinical mastitis, despite the absence of clin-ical manifestations of the disease, reduces the milk productivity of cows by 10-15%, which leads to a loss of up to 700 kg of milk from each cow during the lactation period. To minimize such negative aspects of production, timely and adequate treatment of livestock with the use of modern drugs is necessary.
title: ГИСТОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ В ПЕЧЕНИ У ЛАБОРАТОРНЫХ ЖИВОТНЫХ ЗАРАЖЕННЫХ MYCOBACTERIA BOVIS
title: HISTOLOGICAL CHANGES IN THE LIVER IN LABORATORY AN-IMALS INFECTED WITH MYCOBACTERIA BOVIS
Creators: name: Кособоков, Е.А.
name: Дудоладова, Т.С.
name: Дягилева, Д.А.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: В статье отображено сравнение, изменений в печени после инфицирования патогенной культурой Mycobacteria bovis штамм 8, на разных сроках инокулирования. Этот опыт поз-воляет нам более детально изучить течение патологического процесса и механизм разви-тия болезни. Исследования проводились гистологическим методом. При заражении ти-пичным штаммом было выявлено, что на поздних сроках инфицирования, патологические изменения в органе более выражены.
description: The article displays a comparison of changes in the liver after infection with the pathogenic culture of Mycobacteria bovis strain 8, at different periods of inoculation. This experience allows us to study in more detail the course of the pathological process and the mechanism of the development of the disease. Studies were conducted by the histological method. When infected with a typical strain, it was found that in the later stages of infection, pathological changes in the organ are more pronounced.
title: СТИМУЛЯЦИЯ РОСТА И РАЗВИТИЯ ТЕЛЯТ
title: STIMULATION OF THE GROWTH AND DEVELOPMENT OF CALVES
Creators: name: Кучерявенко, А.В.
name: Головань, В.Т.
name: Юрин, Д.А.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: Приводится сравнение развития внутренних органов и мясных качеств телят при разном уровне скармливания молочных кормов. По сравнению со сверстниками, выращенными в основном на молоке, телята, получавшие комбикорм-стартер, имели лучшее развитие кишечного тракта и всех отделов желудка: рубца, сетки, книжки и сычуга на 66,8-99,3 %. У телят, выращенных на комбикорме-стартере, лучше развиты внутренние органы: почки, сердце, легкие и селезенка на 14,1-33,1 %. Они имели более развитый язык на 33,1 % и голову, чем животные, питавшиеся в основном молоком. У бычков, получавших больше комбикорма и меньше молока, вес туши составил в среднем 102,91 кг, выход мяса 51,2 %, у сверстников второй группы соответственно 110,21 кг, 52,5 %.
description: A comparison is made of the development of internal organs and meat qualities of calves at dif-ferent levels of feeding dairy feeds. Compared with peers grown mainly in milk, calves fed feed starter had the best development of the intestinal tract and all parts of the stomach: cicatrix, nets, books and abomasum by 66.8-99.3%. In calves grown on starter feed, internal organs are better developed: kidneys, heart, lungs and spleen by 14.1-33.1%. They had a more developed tongue by 33.1% and head than animals that fed mostly milk In bulls that received more feed and less milk, the weight of the carcass averaged 102.91 kg, meat output 51.2%, in the peers of the se-cond group, respectively, 110.21 kg, 52.5%.
LCAAJ audio for location 47225 (Tăşnad, Romania)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Tăşnad, Romania (47.477222, 22.583889)
Phase diagram and critical behavior of the random ferromagnet $Ga_{1-x}Mn_xN$
Creators: name: Stefanowicz, S.
name: Kunert, G.
name: Simserides, C.
name: Majewski, J. A.
name: Stefanowicz, W.
name: Kruse, C.
name: Figge, S.
name: Li, Tian
name: Jakiela, R.
name: Trohidou, K. N.
name: Bonanni, A.
name: Hommel, D.
name: Sawicki, M.
name: Dietl, T.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Molecular beam epitaxy has been employed to obtain Ga1-xMnxN films with x up to 10% and Curie temperatures T_C up to 13 K. The magnitudes of T_C and their dependence on x, T_C(x) ~ x^m, where m = 2.2 +/- 0.2 are quantitatively described by a tight binding model of superexchange interactions and Monte Carlo simulations of T_C. The critical behavior of this dilute magnetic insulator shows strong deviations from the magnetically clean case (x = 1), in particular, (i) an apparent breakdown of the Harris criterion; (ii) a non-monotonic crossover in the values of the susceptibility critical exponent gamma_eff between the high temperature and critical regimes, and (iii) a smearing of the critical region, which can be explained either by the Griffiths effects or by macroscopic inhomogeneities in the spin distribution with a variance Delta x = (0.2 +/- 0.1)%.
description: 5 pages, 5 figures
Scalability of single-use biopharmaceutical manufacturing processes using process analytical technology (PAT) tools
Creators: name: Metze, Sabrina
Publisher: name: Hannover : Institutionelles Repositorium der Leibniz Universität Hannover
Year: 2020
Subjects: subject: Tierzellkultivierung
subject: Einwegbioreaktor
subject: Technologien zur Prozessanalytik
subject: Skalierbarkeit
subject: Dewey Decimal Classification::600 | Technik::660 | Technische Chemie

description: Monoclonal antibodies (mAbs) are key molecules in biopharmaceutical manufacturing with important therapeutic use such as anticancer drugs. Mammalian cells serve as production hosts for mAbs. However, mammalian cell culture processes are complex and development timelines for new processes are long. To overcome these challenges the industry is moving towards high-throughput, single-use bioreactors and intensified processes. The scalability in both directions (scale-down and scale-up) is a key step towards fast and economic process development. Moreover, novel Process Analytical Technology (PAT) tools aim at improving process understanding and establishing process control and automation resulting in high and consistent product quality. In the first part of this PhD thesis a method to transfer an existing Chinese Hamster Ovary (CHO) cell culture fed-batch process platform into a semi-perfusion process with threefold higher cumulative product titers was developed. Design of Experiment (DoE) as a powerful PAT tool to screen medium and feed compositions speeded up significantly the semi-perfusion process development. The process transfer to a small scale, single-use bioreactor enabled process control for important parameters such as pH and dissolved oxygen (DO) while keeping the experimental costs low. However, important process attributes (e.g. Viable Cell Concentrations (VCC)) were measured offline limiting the automation possibilities. The second part of this thesis demonstrated how the implementation of an advanced inline capacitance sensor can support online monitoring of important biomass related changes in cell culture. The sensor implementation was proven to be scale-independent in single-use bioreactors (50 L up to 2000 L). Additionally, the transferability of the method to different CHO fed-batch processes was demonstrated. The Wet Cell Weight (WCW) and Viable Cell Volume (VCV) were predicted for the complete cultivation duration within an acceptance criterion based on the offline reference method. The VCC, however, correlated with the permittivity signal only until the end of the exponential growth phase due to the single-frequency measurement dependency on cell diameter changes. The third part of this PhD thesis successfully tested the inline capacitance sensor in frequency scanning mode to predict VCCs over the complete culture time by establishing a robust Multivariate Data Analysis (MVDA) model. A small scale bioreactor system served as method development tool. Therefore, a fast and economic development of a robust MVDA model was demonstrated, highlighting the benefits of scale-down models in biopharmaceutical manufacturing.
title: ПРИРОДНОЕ КОРМОВОЕ СЫРЬЕ
title: NATURAL FEED RAW MATERIALS
Creators: name: Лабутина, Н.Д.
name: Осепчук, Д.В.
name: Хорин, Б.В.
name: Гнеуш, А.Н.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: На сегодня в условиях интенсивного заиления степных водоемов вследствие активного антропогенного воздействия на экосистемы встает вопрос об изъятии донных отложений и использовании их в качестве удобрений или сырья для изготовления кормовых доба-вок. В статье приводятся результаты исследования, которые говорят о том, что добав-ление гуминовых кислот в рацион кур-несушек положительно сказывается на их разви-тии, повышая живую массу птицы и увеличивая яйценоскость
description: Today, in conditions of intensive sedimentation silt of steppe reservoirs due to active anthropogenic impact on ecosystems, the question arises of the removal of bottom sediments and their use as fertilizers or raw materials for the manufacture of feed additives. The article presents the results of the study, which suggest that adding humic acids to the diet of laying hens has a positive effect on their development, increasing the live weight of the bird and increasing egg production.
Role of polysialic acid and NCAM in interneuron development
Creators: name: Röckle, Iris Melanie
Publisher: name: Hannover : Gottfried Wilhelm Leibniz Universität Hannover
Year: 2010
Subjects: subject: Interneuron development
subject: polysialic acid
subject: cell adhesion
subject: Interneuronenentwicklung
subject: Polysialinsäure
subject: Zelladhäsion
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: [no abstract]
title: Jean-Charles Moretti und Dominique Tardy (Hrsg.), L’architecture funéraire monumentale. La Gaule dans l’Empire romain
Creators: name: Panhuysen, Titus
Publisher: name: University Library Heidelberg
Year: 2016

description: Rezension zu: Jean-Charles Moretti und Dominique Tardy (Hrsg.), L’architecture funéraire monumentale. La Gaule dans l’Empire romain. Archéologie et histoire de l’art 24. Editions du Comité des Travaux historiques et scientifiques, Paris 2006. 522 Seiten, zahlreiche Abbildungen
LCAAJ audio for location 46272 (Ivești, Romania)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Ivești, Romania (46.183333, 27.533333)
title: Hartwin Brandt und Frank Kolb, Lycia et Pamphylia. Eine römische Provinz im Südwesten Kleinasiens
Creators: name: Bartels, Jens
Publisher: name: University Library Heidelberg
Year: 2016

description: Rezension zu: Hartwin Brandt und Frank Kolb, Lycia et Pamphylia. Eine römische Provinz im Südwesten Kleinasiens. Orbis Provinciarum. Philipp von Zabern, Mainz 2005. vi und 146 Seiten, 176 Abbildungen
Analytic investigations on the susceptibility of nonlinear analog circuits to substrate noise
Creators: name: Widemann, C.
name: Stegemann, S.
name: John, Werner
name: Mathis, Wolfgang
Publisher: name: Göttingen : Copernicus GmbH
Year: 2013
Subjects: subject: Analytic expressions
subject: Frequency ranges
subject: Model order reduction
subject: Nonlinear analog circuits
subject: Nonlinear elements
subject: Nonlinear statics
subject: Substrate couplings
subject: Taylor series expansions
subject: Analog circuits
subject: Field effect transistors
subject: Frequency response
subject: Substrates
subject: Dewey Decimal Classification::600 | Technik

description: This work deals with the conducted susceptibility of nonlinear analog circuits with respect to substrate noise. The substrate coupling mechanism is modeled by a passive three-terminal network that is obtained by means of the finite element method with a subsequently performed model order reduction. Applying this substrate model to the bulk terminal of MOS transistors in integrated analog circuits, it is possible to examine the influence of substrate noise on the circuit's functionality. By means of a block-oriented approach, analytic expressions for the output behavior of the circuits are found. The utilized multi-input Wiener model separates the linear dynamic from the nonlinear static circuit properties. Due to this separation the frequency response of both signals, i.e.,input signal and substrate noise, respectively, can be identified, and hence, the frequency range in which the circuit is most susceptible to substrate noise. Since the nonlinear static behavior of each MOS transistor depends on two signals, truncated multivariate Taylor series expansions of the nonlinear elements are performed on the basis of the EKV model description (Enz et al., 1995). The proposed modeling is illustrated by a simple example. © 2011 Author(s).
title: ВЛИЯНИЕ СОВМЕСТНОГО ИСПОЛЬЗОВАНИЯ НАНОЧА-СТИЦ Fe (ЖЕЛЕЗА) С ЖИРОСОДЕРЖАЩЕЙ ДОБАВКОЙ ПАЛ-МАТРИКС В СОСТАВЕ РАЦИОНОВ НА ГЕМАТОЛОГИЧЕСКИЕ ПОКАЗАТЕЛИ И НЕСПЕЦИФИЧЕСКИЙ ИММУНИТЕТ ОТ-КАРМЛИВАЕМЫХ БЫЧКОВ
title: THE INFLUENCE OF FAT-CONTAINING SUPPLEMENTS PUL-MATRIX ENRICHED WITH SI NANOPARTICLES IN THE COM-POSITION OF THE DIET ON HEMATOLOGICAL AND NATURAL RESISTANCE OF FATTENED STEERS
Creators: name: Левахин, Ю. И.
name: Нуржанов, Б. С.
name: Джуламанов, Е.Б.
name: Рязанов, В.А.
Publisher: name: ФГБНУ "Северо-Кавказский федеральный научный аграрный центр"
Year: 2019

description: В данной статье представлены результаты проведенного исследования по влиянию жиро-содержащей добавки Палматрикс обогащённой разными дозами наночастиц железа в со-ставе рационов на гематологические показатели и естественную резистентность подопыт-ных бычков. На основании проведенного эксперимента было установлено, что использо-вание жиросодержащих добавок в комплексе с наночастицами Fe в составе рационов в ко-личестве 362,6 мг/гол, является оптимальной которая способствует улучшению показате-лей крови и иммунологического статуса животных.
description: This article presents the results of the conducted research on the impact of fat-containing sup-plements Pulmatrix enriched with different doses of iron nanoparticles in the composition of di-ets on hematological parameters and natural resistance of the experimental steers. On the basis of the experiment it was found that the use of fat-containing additives complete with Fe nano-particles in the diet in the amount of 362.6 mg/head, is optimal which improves blood counts and immunological status of animals.
Reconstructing the Subsurface Three-Dimensional Magnetic Structure of A Solar Active Region Using SDO/HMI Observations
Creators: name: Chintzoglou, Georgios
name: Zhang, Jie
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: A solar active region (AR) is a three-dimensional magnetic structure formed in the convection zone, whose property is fundamentally important for determining the coronal structure and solar activity when emerged. However, our knowledge on the detailed 3-D structure prior to its emergence is rather poor, largely limited by the low cadence and sensitivity of previous instruments. Here, using the 45-second high-cadence observations from the Helioseismic and Magnetic Imager (\emph{HMI}) onboard the Solar Dynamics Observatory (\emph{SDO}), we are able for the first time to reconstruct a 3-D datacube and infer the detailed subsurface magnetic structure of NOAA AR 11158 and to characterize its magnetic connectivity and topology. This task is accomplished with the aid of the image-stacking method and advanced 3-D visualization. We find that the AR consists of two major bipoles, or four major polarities. Each polarity in 3-D shows interesting tree-like structure, i.e. while the root of the polarity appears as a single tree-trunk-like tube, the top of the polarity has multiple branches consisting of smaller and thinner flux-tubes which connect to the branches of the opposite polarity that is similarly fragmented. The roots of the four polarities align well along a straight line, while the top branches are slightly non-coplanar. Our observations suggest that an active region, even appearing highly complicated on the surface, may originate from a simple straight flux-tube that undergoes both horizontal and vertical bifurcation processes during its rise through the convection zone.
description: 11 pages, 4 figures and 2 online videos. Accepted to appear on Astrophysical Journal Letters (ApJL)
Deciding circular-arc graph isomorphism in parameterized logspace
Creators: name: Chandoo, Maurice
Publisher: name: Wadern : Schloss Dagstuhl- Leibniz-Zentrum für Informatik GmbH, Dagstuhl Publishing
Year: 2016
Subjects: subject: Canonical representation
subject: Graph isomorphism
subject: Parameterized algorithm
subject: Set theory
subject: Canonical representations
subject: Cardinalities
subject: Circular arc
subject: Circular-arc graph
subject: Parameterized
subject: Space algorithms
subject: Graphic methods
subject: Konferenzschrift
subject: Dewey Decimal Classification::100 | Philosophie

description: We compute a canonical circular-arc representation for a given circular-arc (CA) graph which implies solving the isomorphism and recognition problem for this class. To accomplish this we split the class of CA graphs into uniform and non-uniform ones and employ a generalized version of the argument given by Köbler et al. (2013) that has been used to show that the subclass of Helly CA graphs can be canonized in logspace. For uniform CA graphs our approach works in logspace and in addition to that Helly CA graphs are a strict subset of uniform CA graphs. Thus our result is a generalization of the canonization result for Helly CA graphs. In the non-uniform case a specific set Omega of ambiguous vertices arises. By choosing the parameter k to be the cardinality of Omega this obstacle can be solved by brute force. This leads to an O(k + log(n)) space algorithm to compute a canonical representation for non-uniform and therefore all CA graphs.
LCAAJ audio for location 47272 (Iaşi, Romania)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Iaşi, Romania (47.156944, 27.590278)
LCAAJ audio for location 47233 (Dej, Romania)
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2021
Subjects: Yiddish language--Dialects
Yiddish language--Phonology
Language surveys
Ashkenazim--Social life and customs
Jews--Civilization

description: Dej, Romania (47.141588, 23.878734)
Space Division Multiplexing in Optical Fibres
Creators: name: Richardson, D. J.
name: Fini, J. M.
name: Nelson, L E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Optical communications technology has made enormous and steady progress for several decades, providing the key resource in our increasingly information-driven society and economy. Much of this progress has been in finding innovative ways to increase the data carrying capacity of a single optical fibre. In this search, researchers have explored (and close to maximally exploited) every available degree of freedom, and even commercial systems now utilize multiplexing in time, wavelength, polarization, and phase to speed more information through the fibre infrastructure. Conspicuously, one potentially enormous source of improvement has however been left untapped in these systems: fibres can easily support hundreds of spatial modes, but today's commercial systems (single-mode or multi-mode) make no attempt to use these as parallel channels for independent signals.
description: to appear in Nature Photonics
Transition-Metal-Stabilized Heavy Tetraphospholide Anions
Creators: name: Kelly, John A.
name: Streitferdt, Verena
name: Dimitrova, Maria
name: Westermair, Franz F.
name: Gschwind, Ruth Maria
name: Berger, Rafael J. F.
name: Wolf, Robert
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: 540 Chemie

description: Phosphorus analogues of the ubiquitous cyclopentadienyl (Cp) are a rich and diverse family of compounds, which have found widespread use as ligands in organometallic complexes. By contrast, phospholes incorporating heavier group 14 elements (Si, Ge, Sn, and Pb) are hardly known. Here, we demonstrate the isolation of the first metal complexes featuring heavy cyclopentadienyl anions SnP42– and PbP42–. The complexes [(η4-tBu2C2P2)2Co2(μ,η5:η5–P4Tt)] [Tt = Sn (6), Pb (7)] are formed by reaction of white phosphorus (P4) with cyclooctadiene cobalt complexes [Ar′TtCo(η4-P2C2tBu2)(η4–COD)] [Tt = Sn (2), Pb (3), Ar′ = C6H3-2,6{C6H3-2,6-iPr2}2, COD = cycloocta-1,5-diene] and Tt{Co(η4-P2C2tBu2)(COD)}2 [Tt = Sn (4), Pb (5)]. While the SnP42– complex 6 was isolated as a pure and stable compound, compound 7 eliminated Pb(0) below room temperature to afford [(η4-tBu2C2P2)2Co2(μ,η4:η4–P4) (8), which is a rare example of a tripledecker complex with a P42– middle deck. The electronic structures of 6–8 are analyzed using theoretical methods including an analysis of intrinsic bond orbitals and magnetic response theory. Thereby, the aromatic nature of P5– and SnP42– was confirmed, while for P42–, a specific type of symmetry-induced weak paramagnetism was found that is distinct from conventional antiaromatic species.
Real Time scheduling with Virtual Nodes for Self Stabilization in Wireless Sensor Networks
Creators: name: Virmani, Deepali
name: Jain, Satbir
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: In this paper we propose a new scheduling algorithm called Real Time Scheduling (RTS) which uses virtual nodes for self stabilization. This algorithm deals with all the contributing components of the end-to-end travelling delay of data packets in sensor network and with virtual nodes algorithm achieves QoS in terms of packet delivery, multiple connections, better power management and stable routes in case of failure. RTS delays packets at intermediate hops (not just prioritizes them) for a duration that is a function of their deadline. Delaying packets allows the network to avoid hot spotting while maintaining deadline-faithfulness. We compare RTS with another prioritizing and scheduling algorithm for real-time data dissemination in sensor networks, velocity monotonic scheduling. This paper simulates RTS based on two typical routing protocols, shortest path routing and greedy forwarding with J-Sim.
description: arXiv admin note: substantial text overlap with arXiv:cs/0608069 by other authors without attribution
Oenothera biennis L.
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: O. biennis L. Cat. 145. l: St-Maurice (Marietan); Les Marecottes, an der neuen Strasse, 1030m (Coquoz; Wurgler 1952).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Anisotropic dispersion and partial localization of acoustic surface plasmons on an atomically stepped surface: Au(788)
Creators: name: Smerieri, M.
name: Vattuone, L.
name: Savio, L.
name: Langer, Thomas
name: Tegenkamp, Christoph
name: Pfnür, Herbert
name: Silkin, V.M.
name: Rocca, M.
Publisher: name: College Park, MD : American Physical Society
Year: 2014
Subjects: subject: Anisotropic dispersion
subject: Intersubband transitions
subject: Monoatomic steps
subject: Multiple surfaces
subject: Partial localization
subject: Stepped surfaces
subject: Surface plasmons
subject: Vicinal surface
subject: Plasmons
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: Understanding acoustic surface plasmons (ASPs) in the presence of nanosized gratings is necessary for the development of future devices that couple light with ASPs. We show here by experiment and theory that two ASPs exist on Au(788), a vicinal surface with an ordered array of monoatomic steps. The ASPs propagate across the steps as long as their wavelength exceeds the terrace width, thereafter becoming localized. Our investigation identifies, for the first time, ASPs coupled with intersubband transitions involving multiple surface-state subbands. © 2014 American Physical Society.
title: A Simple Deep Learning Architecture for City-scale Vehicle Re-identification
Creators: name: Kamenou, Eleni
Publisher: name: TU Dublin
Year: 2019

description: The task of vehicle re-identification aims to identify a vehicle across different cameras with non overlapping fields of view and it is a challenging research problem due to viewpoint orientation, scene occlusions and intrinsic inter-class similarity of the data. In this paper, we propose a simplistic approach for one-shot vehicle re-identification based on a siamese/triple convolutional architecture for feature representation. Our method involves learning a feature space in which the vehicles of the same identities are projected closer to one another compared to those with different identities. Moreover, we provide an extensive evaluation of loss functions, including a novel combination of triplet loss with classification loss, and other network parameters applied to our vehicle re-identification system. Compared to most existing state-of-the-art approaches, our approach is simpler and more straightforward for training, utilizing only identity-level annotations. The proposed method is evaluated on the large-scale CityFlow-ReID dataset.
Tunneling magneto thermocurrent in CoFeB/MgO/CoFeB based magnetic tunnel junctions
Creators: name: Liebing, Niklas
name: Serrano-Guisan, Santiago
name: Krzysteczko, Patryk
name: Rott, Karsten
name: Reiss, Günter
name: Langer, Jürgen
name: Ocker, Berthold
name: Schumacher, Hans Werner
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We study the tunneling magneto thermopower and tunneling magneto thermocurrent of CoFeB/MgO/CoFeB magnetic tunnel junctions (MTJ). The devices show a clear change of the thermoelectric properties upon reversal of the magnetisation of the CoFeB layers from parallel to the antiparallel orientation. When switching from parallel to antiparallel the thermopower increases by up to 55% where as the thermocurrent drops by 45%. These observations can be well explained by the Onsager relations taking into account the tunneling magneto resistance of the MTJ. These findings contrast previous studies on AlO based MTJ systems, revealing tunneling magneto thermo power but no tunneling magneto thermocurrent.
description: 9 pages, 3 figures
Fake Run-Time Selection of Template Arguments in C++
Creators: name: Langr, Daniel
name: Tvrdík, Pavel
name: Dytrych, Tomáš
name: Draayer, Jerry P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: C++ does not support run-time resolution of template type arguments. To circumvent this restriction, we can instantiate a template for all possible combinations of type arguments at compile time and then select the proper instance at run time by evaluation of some provided conditions. However, for templates with multiple type parameters such a solution may easily result in a branching code bloat. We present a template metaprogramming algorithm called for_id that allows the user to select the proper template instance at run time with theoretical minimum sustained complexity of the branching code.
description: Objects, Models, Components, Patterns (50th International Conference, TOOLS 2012)