cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Analysing The Impact Of Technological Innovation On Health Service Delivery: A Case Study Of Nhs Uk"
Creators: name: Braimer, David
Publisher: name: Zenodo
Year: 2018
Subjects: Technological Innovation, Health Service Delivery, NHS, UK

description: Technological innovation is one of the biggest blessings in health service sector by which the

sector has to embrace today’s advanced form of growth and innovation. This study tends to

explore the impact of technological innovation in the health service delivery in NHS UK. NHS is

the public health service provider of the UK that provides quality and free health care services to

its citizen expect charges in some cases. The main objectives of this study are to analyse the

technological innovations employed in in NHS, its features, its impacts on health service

delivery along with findings ways to improve quality of health care.

In the study, both primary and secondary sources of data and information are collected. A

literature review was conducted by including literature from 2000 AD and onwards. A

conceptual framework has been developed basing on the literature review. Likewise, an online

survey (questionnaire) was conducted among the 60 participants that include patients and staffs

of NHS (31 service user and 29 service provider). The participants were selected the through the

use non-probability purposive sampling method.

The major findings of the study depict that technological innovation has a positive impact on the

health service delivery in NHS UK. The findings reveal that easy and fast diagnosis and

treatment, enhanced quality and standard, improved efficiency and service, reduction in medical

errors, better research and development, improved efficiency and better communication within

and outside are the impacts that technological innovations. However, few of the negative impacts

like a high cost for the service user and mistakes due to technical defects have been found in this

study. Towards the end some of the recommendations are provided basing on the findings of the

study.
title: Ingeborg Bachmann. Interviews
Creators: name: Pötsch, Katharina
Year: 2009

description: Es handelt sich um die Analyse von in Printmedien erschienenen Interviews, die Ingeborg Bachmann im Zeitraum von 1971 bis 1973 gegeben hat. Das Hauptaugenmerk wird gerichtet auf die Themen, die Verläufe sowie die rhetorischen Strategien. Zum Vergleich wird eine Interview-Karikatur des Romans "Malina" herangezogen und das ambivalente Verhältnis der Autorin zu jener Form des öffentlichen Auftritts versucht zu beleuchten. Die Original-Interviews sind im Anhang zu finden.
Additional file 3 of Effect of transcutaneous electrical acupoint stimulation on the quality of postoperative recovery: a meta-analysis
Creators: name: Zhang, Meng
name: Zhang, Huanhuan
name: Li, Pan
name: Li, Jianli
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Science Policy

description: Supplementary Material 3
“Smartphone apps are cool, but do they help me?”: A qualitative interview study of adolescents’ perspectives on using smartphone interventions to manage nonsuicidal self-injury
Creators: name: Čuš, Anja
name: Edbrooke-Childs, Julian
name: Ohmann, Susanne
name: Plener, Paul L.
name: Akkaya-Kalayci, Türkan
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: NSSI
subject: mHealth
subject: smartphone apps
subject: adolescence
subject: qualitative study
subject: user perspectives
subject: user engagement
subject: design framework
subject: design implications
subject: DDC 610 / Medicine & health
subject: Mental health
subject: Mobile applications
subject: Telemedicine
subject: Self-injurious behavior
subject: Adolescent
subject: Telemedizin
subject: Psychische Gesundheit
subject: Jugend
subject: Selbstbeschädigung

description: Nonsuicidal self-injury (NSSI) is a major mental health problem associated with negative psychosocial outcomes and it most often starts in early adolescence. Despite this, adolescents are rarely involved in informing the development of interventions designed to address their mental health problems. This study aimed to (1) assess adolescents’ needs and preferences about future interventions that are delivered through smartphones and (2) develop a framework with implications for designing engaging digital mental health interventions. Fifteen adolescent girls, aged 12–18 years, who met diagnostic criteria for a current NSSI disorder and were in contact with mental health services, participated in semi-structured interviews. Following a reflexive thematic analysis approach, this study identified two main themes: (1) Experiences of NSSI (depicts the needs of young people related to their everyday experiences of managing NSSI) and (2) App in Context (portrays preferences of young people about smartphone interventions and reflects adolescents’ views on how technology itself can improve or hinder engaging with these interventions). Adolescent patients expressed interest in using smartphone mental health interventions if they recognize them as helpful, relevant for their life situation and easy to use. The developed framework suggests that digital mental health interventions are embedded in three contexts (i.e., person using the intervention, mental health condition, and technology-related factors) which together need to inform the development of engaging digital resources. To achieve this, the cooperation among people with lived experience, mental health experts, and human computer interaction professionals is vital.
Evaluation of relationship between SPON1 gene and genetic susceptibility of postmenopausal osteoporosis
Creators: name: Ma, Wenlong
name: Chen, Ke
name: Xiao, Wenqing
name: Tang, Hongtao
name: Wang, Shaohui
name: Wang, Kunzheng
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Hematology

description: Postmenopausal osteoporosis (PMOP) is one of systemic bone degenerative diseases characterised by decreased bone mineral density (BMD). Previous studies suggest that the SPON1 gene may be associated with BMD and play an important role in the occurrence and development of PMOP. In this study, we aimed to investigate the potential association between PMOP and the SPON1 gene. A total of 8062 postmenopausal women comprising 2684 primary PMOP patients, and 5378 healthy controls were recruited. Forty tag SNPs were selected for genotyping to evaluate the association of the SPON1 gene with PMOP and BMD. Genetic association and bioinformatics analyses were performed for PMOP. SNP rs2697825 was identified to be significantly associated with the risk of PMOP at both allelic (T-statistics = −3.84, p = .0001) and genotypic levels (χ2=15.86, p = .0004). The G allele of SNP rs2697825 was significantly associated with a decreased risk of PMOP with an OR [95%] of 0.84 [0.77–0.92]. The G allele of SNP rs2697825 was associated with increased BMD at both the lumbar spine and femoral neck. Our results provide further evidence to support the important role for the SPON1 gene in the aetiology of PMOP, adding to the current understanding of the susceptibility to osteoporosis.
A metabolomic study on the anti-depressive effects of two active components from Chrysanthemum morifolium
Creators: name: Liu, Tong
name: Zhou, Ning
name: Xu, Ruihao
name: Cao, Yangang
name: Zhang, Yanli
name: Liu, Zhen
name: Zheng, Xiaoke
name: Feng, Weisheng
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mental Health

description: Chrysanthemum morifolium (Chr) is a traditional Chinese medicine (TCM) that has been used in the treatment of inflammation-linked diseases for hundreds of years. Naringenin (Nar) and apigenin (Api) are the major active components in aqueous extracts of C. morifolium. The aim of our study was to clarify the roles of Chr, Nar and Api in ameliorating depression-like behaviour induced by corticosterone. First, the behavioural and biochemical indicators closely related to depression were examined to evaluate the therapeutic effects of Chr/Nar/Api on a depression model. Then, a metabolomics approach was utilized to screen for biomarkers and related pathways between a control group and Chr/Nar/Api groups. The comprehensive results revealed that Chr/Nar/Api exerted anti-depressant effects through interfering with tryptophan metabolism, arginine and prolinemetabolism, citrate cycle, niacin and niacinamide metabolism, phenylalanine metabolism, and alanine, aspartate and glutamate metabolism. The mechanism of Chr/Api/Nar in the treatment of depression was elucidated based on material and energy metabolism. Moreover, Nar could be used as a substitute for Chr for reversing depression-like behaviour, and Api was similar to a positive drug in terms of function on depression. The integrated metabolomics approach demonstrated here should be an effective method for interpreting the function of herbs from TCM and clarifying the mechanism of their components in future studies.
Additional file 4 of Intradiol ring cleavage dioxygenases from herbivorous spider mites as a new detoxification enzyme family in animals
Creators: name: Njiru, Christine
name: Xue, Wenxin
name: De Rouck, Sander
name: Alba, Juan M.
name: Kant, Merijn R.
name: Chruszcz, Maksymilian
name: Vanholme, Bartel
name: Dermauw, Wannes
name: Wybouw, Nicky
name: Van Leeuwen, Thomas
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 4: File S3. Coverage plots of 17 T. urticae DOG genes and their surrounding regions in the genome of Tetranychus urticae. Gene models of DOG genes and their neighboring genes are depicted as follows: large and small orange boxes represent coding sequences and untranslated regions, respectively, whereas introns are shown as connecting lines between the boxes. (+) and (-) represent the forward and reverse strand, respectively. Underneath the gene models of TuDOG7, TuDOG10 and TuDOG11, the length and position of an amplicon obtained by PCR (Fig. S4) is indicated with a red line. Next, coverage plots of Illumina-reads (‘“Illu.’”) from adult T. urticae polyA selected RNA [13] and from genomic DNA sequencing of the EtoxR (‘“Etox’”) and London(‘“Lon’”) strain of T. urticae [13, 110] are shown below the gene models. The Illumina reads coverage plots are followed by a coverage plot of Sanger (‘“San.’”) reads from genomic DNA sequencing of the London strain [13] and by an alignment of these Sanger reads with the T. urticae genome of the London strain. Paired-end Sanger reads for which both reads are mapped in or extend nearby the indicated region are denoted by thin lines to show pair connections [13] (see [43], for mapping details).
Additional file 1 of Comparison of diffusion ranges at different local anesthetic volumes during superior laryngeal nerve block
Creators: name: Bao, Yin
name: Wang, Huijun
name: Li, Lifeng
name: Xu, Hongbo
name: Li, Yun
name: Wang, Guyan
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 1.
title: Zugangsmotive von Studierenden für das Lehramtsstudium im Unterrichtsfach "Bewegung und Sport"
Creators: name: Marszalek, Elisabeth
Year: 2009

description: Das Ziel der vorliegenden Arbeit ist es, einen differenzierten Einblick in die Motive der Studierenden, auf deren Grundlage sie das Lehramtstudium im Unterrichtsfach „Bewegung und Sport“ gewählt haben, zu bekommen. Längerfristig soll das Ergebnis dazu verwendet werden, Fragebögen zu entwickeln, mit deren Hilfe Studierende gezielt für diese Studienrichtung ausgewählt werden können. Der theoretische Teil dieser Arbeit befasst sich zu Beginn mit der Lehrerforschung. Es werden die empirischen Ergebnisse der Lehrerforschung präsentiert und grundlegende Theorien der Persönlichkeitsmerkmale von Lehrern sowie der aktuelle Stand der Forschung bezüglich dem zeitgemäßen Anforderungsprofil von Lehrern vorgestellt. Speziell wird auf den Lehrer im Unterrichtsfach „Bewegung und Sport“ eingegangen. Die verschiedenen Positionen zu bedungenen Lehrerkompetenzen und -eigenschaften werden dargelegt und die Merkmale des schulischen Sportunterrichts angeführt. Die Erläuterung der positiven und negativen Aspekte des Sportlehrerberufs, sowie der Arbeitsbedingungen und Unterrichtsbelastungen der Sportlehrer schließen das erste Kapitel des theoretischen Teiles ab. Der zweite Teil beschäftigt sich mit dem Thema „Berufswahlmotive“. Es werden die wichtigsten Begriffe definiert und anschließend die Berufswahlmotive der Lehrer im Allgemeinen aber auch der Sportlehrer im Speziellen beleuchtet. Der letzte Teil des theoretischen Blocks befasst sich mit der qualitativen Sozialforschung. Es wird ein Methodenüberblick gegeben und die qualitative Sozialforschung vorgestellt. Ihre Prinzipien werden erläutert und Datenerhebungs- und Auswertungsverfahren behandelt. An den theoretischen Teil schließt eine empirische Untersuchung an. Diese befasst sich mit der Auswertung von Motivationsschreiben, die Sportstudenten vor dem Beginn des Studiums am Institut für Sportwissenschaften der Universität Wien, einreichen müssen. Es werden 215 Motivationsschreiben mit Hilfe der zusammenfassenden qualitativen Inhaltsanalyse in Kombination mit der induktiven Kategorienbildung ausgewertet. Die Ergebnisse der Untersuchung werden im Kapitel 5 und 6 dargestellt, beschrieben und im Kapitel 7 zusammengefasst. Der Empirieteil endet mit der Beantwortung und Diskussion der Forschungsfrage.
LncRNA PTENP1 inhibits cervical cancer progression by suppressing miR-106b
Creators: name: Fan, Yingrui
name: Sheng, Weiwei
name: Meng, Yi
name: Cao, Yundi
name: Li, Rong
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: Virology

description: LncRNA PTENP1 is a competitive endogenous RNA (ceRNA) involved in decoying miR-106b in multiple diseases. This study investigates the interaction of PTENP1 and miR-106b in cell proliferation, apoptosis and epithelial–mesenchymal transition (EMT) in cervical cancer. The expressions of PTENP1, miR-106b and PTEN were determined in cervical cancer tissues, adjacent normal tissues, cervical cancer cells (HeLa, SiHa, C33A and CasKi) and normal cervical epithelial H8 cells. Up-regulation of PTENP1 and down-regulation of miR-106b were conducted in HeLa and CasKi cells by transfecting cells with corresponding miRNA mimics and inhibitors. Bioinformatics analysis, luciferase reporter assay and RNA-pull down assay were performed to verify the association of miR-106b, PTEN, and PTENP1. Cell growth and cell apoptosis were determined by CCK-8 and flow cytometry analysis. It was found that the expressions of PTENP1 and PTEN were up-regulated and that of miR-106b were down-regulated in cervical cancer tissues and cells. PTENP1 localized in cytoplasm and competitively bound to miR-106b. Up-regulation of PTENP1 and down-regulation of miR-106b contributed to increased expressions of PTEN and E-cadherin. Decreased expression of miR-106b, ZEB1, Snail and Vimentin, resulted in inhibiting cell proliferation and promoting cell apoptosis. Over-expression of PTENP1 and miR-106b accelerated cell proliferation and slowed down cell apoptosis. miR-106b inhibited the expression of PTEN. Our results suggest that LncRNA PTENP1 inhibits cervical cancer progression by competitively binding to miR-106b, leading to promote PTEN expression, inhibit cell proliferation and EMT and induce cell apoptosis in cervical cancer cells
An introduction to TkGofer
Creators: name: Vullinghs, Ton
name: Schulte, Wolfram
name: Schwinn, Thilo
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Functional programming languages
subject: Funktionale Programmiersprache
subject: GOFER

description: N/A
Break-Glass Access Control Systems in Medical Devices
Creators: name: Loos, Melissa
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: break-glass
subject: access
subject: control
subject: medical
subject: devices
subject: DDC 610 / Medicine & health
subject: DDC 620 / Engineering & allied operations
subject: Medical devices
subject: Kontrolle

description: With medical devices performing life-critical operations on the human body and health-related data being classified as very sensitive by the GDPR, we expect data and functionalities in healthcare devices to be secured in the best way possible. However, security measures of medical devices have been highly neglected in the past. Modern security research usually fails to address the specific needs of healthcare, with the contradiction between emergency access and security being a central issue. Until today, no informative overview on break-glass access control systems seems to exist in academic literature. To address this issue, this paper describes both currently used and purely academic break-glass mechanisms, and discusses the benefits and drawbacks of each solution to provide a better understanding of the conflict between safety and security. Hopefully, this paper will motivate security researchers to further investigate possible solutions for break-glass access controls in medical devices.
sj-docx-1-fap-10.1177_09593535231217135 - Supplemental material for The practical realization of the feminist welfare state: Equal sharing and gender equality in institutional interaction about parental leave in Sweden
Creators: name: Höglund, Frida
name: Flinkfeldt, Marie
Publisher: name: SAGE Journals
Year: 2023
Subjects: Gender studies
Psychology not elsewhere classified

description: Supplemental material, sj-docx-1-fap-10.1177_09593535231217135 for The practical realization of the feminist welfare state: Equal sharing and gender equality in institutional interaction about parental leave in Sweden by Frida Höglund and Marie Flinkfeldt in Feminism & Psychology
Simulation supported analysis of the effect of SiNx interlayers in AlGaN on the dislocation density reduction
Creators: name: Klein, Olaf P.
name: Biskupek, Johannes
name: Kaiser, Ute
name: Forghani, Kamran
name: Thapa, Sarad Bahadur
name: Scholz, Ferdinand
name: Dc.Contributor.Author
Publisher: name: Universität Ulm
Year: 2010
Subjects: subject: ALN LAYERS
subject: DDC 530 / Physics
subject: DDC 570 / Life sciences
subject: Growth
subject: MOCVD-Verfahren

description: SiNx interlayers can act as anti-surfactants and drastically reduce the dislocation density in pure GaN layers. In our work we could observe a very efficient dislocation annihilation of the a-type threading dislocations (TD) at a fractional SiNx monolayer even in AlxGa1−xN layers with relatively high Al content of x=0.2, grown on c-plane sapphire by MOVPE. The investigations were focused on the effect of the SiNx interlayer on the dislocation density reduction of the a-type TDs. Weak-beam dark-field (WBDF) and high-resolution (HR) TEM analyses directly at the SiNx interface indicate that the most frequently occurring effect for the reduction of the a-type TDs is the conversion of an a-type TD into an a-type basal dislocation due to lateral overgrowth of SiNx by AlGaN. To confirm this effect, an appropriate dislocation model was developed for the a-type TD in AlGaN and its bending due to the SiNx nano-mask. Corresponding image calculations were performed and compared with the experiments.
MACHINE LEARNING AND EXPLAINABLE AI FOR SCHEDULING IN DELIVERY LOGISTICS
Creators: name: Kim, Yonggab
Publisher: name: Purdue University Graduate School
Year: 2025
Subjects: classificationCode: 401404
subject: Industrial engineering

description: This dissertation explores the integration of machine learning and XAI to address scheduling and dispatching challenges in three critical logistics environments: UAV-based delivery systems, OHT in semiconductor manufacturing, and last-mile delivery operations, exemplified by the Amazon Last Mile Challenge. Each of these areas presents unique logistical hurdles, from managing UAV payload limitations and battery life to coordinating hundreds of vehicles in OHT systems and balancing drivers’ preferences in last-mile delivery. By investigating these diverse contexts, this work aims to develop and validate novel scheduling solutions that leverage the strengths of machine learning while ensuring explainability through XAI.
title: Die interkulturelle Kommunikation in der österreichisch-ungarischen Gewerkschaftsarbeit unter Berücksichtigung der Terminologie im Wandel der Zeit
Creators: name: Szondy, Katalin
Year: 2009

description: In Zeiten der Globalisierung, innerhalb welcher der gesamte Arbeitsmarkt großen und einschneidenden Veränderungen unterliegt und die Nationalstaaten zugunsten der multinationalen Konzerne immer mehr an Bedeutung und Macht verlieren, befinden sich die Arbeitnehmer in einer zunehmend schwierigen und teilweise auch unsicheren Lage. Da erscheint es beinahe selbstverständlich, dass den Gewerkschaften, die mit dem Grundgedanken des Interessensschutzes der Arbeitnehmer gegründet wurden, und insbesondere der internationalen Gewerkschaftszusammenarbeit eine besondere Bedeutung zukommt. In der vorliegenden Arbeit wird die Kommunikation in der österreichisch-ungarischen Gewerkschaftszusammenarbeit näher beleuchtet und analysiert werden. In meiner Hypothese gehe ich davon aus, dass die Mitarbeiter des ÖGB in der Lage waren den Regeln der interkulturellen Kommunikation entsprechend kompetent zu kommunizieren. Die zentrale Fragestellung dabei ist, welche kommunikativen Faktoren darauf deuten, ob die erfolgreiche Kommunikation auf der interkulturellen Ebene bewusst oder unbewusst geschah, und in wie weit die interkulturelle Kompetenz der Akteure eine Garant für eine erfolgreiche und effiziente Kooperation auf dem Gebiet sein kann/konnte? Die Untersuchung der Kommunikation der österreichisch-ungarischen Gewerkschaftszusammenarbeit während drei Dekaden (1970er bis Anfang 2000) soll auch die Veränderungen in der Kommunikation und auch in der Terminologie des Gebietes aufzeigen.
Visualization of the Gödel universe
Creators: name: Buser, Michael
name: Kajari, Endre
name: Schleich, Wolfgang P.
Publisher: name: Universität Ulm
Year: 2013
Subjects: subject: Gödel-Universum
subject: Gödel's universe
subject: DDC 520 / Astronomy
subject: DDC 530 / Physics
subject: General relativity (Physics)
subject: Gödel, Kurt
subject: Time travel
subject: Allgemeine Relativitätstheorie
subject: Gödel, Kurt
subject: Zeitreise

description: The standard model of modern cosmology, which is based on the Friedmann–Lemaître–Robertson–Walker metric, allows the definition of an absolute time. However, there exist (cosmological) models consistent with the theory of general relativity for which such a definition cannot be given since they offer the possibility for time travel. The simplest of these models is the cosmological solution discovered by Kurt Gödel, which describes a homogeneous, rotating universe. Disregarding the paradoxes that come along with the abolishment of causality in such space–times, we are interested in the purely academic question of how an observer would visually perceive the time travel of an object in Gödel's universe. For this purpose, we employ the technique of ray tracing, a standard tool in computer graphics, and visualize various scenarios to bring out the optical effects experienced by an observer located in this universe. In this way, we provide a new perspective on the space–time structure of Gödel's model.
Resolving Mars' Orbital Irregularities, Kirkwood Gaps, and Asteroid Belt Populations Through the Coherence-Dark Coherence Framework
Creators: name: Thavarajah, Rogan
Publisher: name: Zenodo
Year: 2025

description: This study provides a comprehensive mathematical and theoretical analysis of Mars' orbital eccentricity anomalies, the structure of the Asteroid Belt, and the formation of Kirkwood gaps using the Coherence-Dark Coherence Framework. Traditional gravitational models struggle to fully explain the unexpected eccentricity of Mars, the precise periodicity of Kirkwood gaps, and the fractal-like clustering of asteroids, often relying on planetary migration scenarios and collisional evolution.

This work introduces resonance-driven coherence interactions as a predictive mechanism, demonstrating how periodic phasing and dephasing effects influence planetary and small-body orbits. Absolute predictions include:

Long-term oscillatory variations in Mars’ eccentricity (~50 Myr cycles).

Undiscovered minor Kirkwood gaps at ~2.65 AU and additional depletion zones at 3.1 AU and 3.6 AU.

Nested periodic structures in asteroid populations, following a fractal coherence model.

Observational validation is outlined through asteroid belt surveys, Mars' orbital tracking, and future deep-space exploration. This framework offers a self-organizing, predictive alternative to classical models, refining our understanding of planetary and small-body dynamics.
Electron availability in CO2, CO and H2 mixtures constrains flux distribution, energy management and product formation in Clostridium ljungdahlii
Creators: name: Hermann, Maria
name: Teleki, Attila
name: Weitz, Sandra
name: Niess, Alexander
name: Freund, Andreas
name: Bengelsdorf, Frank R.
name: Takors, Ralf
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: DDC 540 / Chemistry & allied sciences
subject: Metabolism
subject: Carbon monoxide
subject: Electrons
subject: Clostridium
subject: Lipidstoffwechsel

description: Acetogens such as Clostridium ljungdahlii can play a crucial role reducing the human CO2 footprint by converting industrial emissions containing CO2, CO and H2 into valuable products such as organic acids or alcohols. The quantitative understanding of cellular metabolism is a prerequisite to exploit the bacterial endowments and to fine-tune the cells by applying metabolic engineering tools. Studying the three gas mixtures CO2 + H2, CO and CO + CO2 + H2 (syngas) by continuously gassed batch cultivation experiments and applying flux balance analysis, we identified CO as the preferred carbon and electron source for growth and producing alcohols. However, the total yield of moles of carbon (mol-C) per electrons consumed was almost identical in all setups which underlines electron availability as the main factor influencing product formation. The Wood–Ljungdahl pathway (WLP) showed high flexibility by serving as the key NAD+ provider for CO2 + H2, whereas this function was strongly compensated by the transhydrogenase-like Nfn complex when CO was metabolized. Availability of reduced ferredoxin (Fdred) can be considered as a key determinant of metabolic control. Oxidation of CO via carbon monoxide dehydrogenase (CODH) is the main route of Fdred formation when CO is used as substrate, whereas Fdred is mainly regenerated via the methyl branch of WLP and the Nfn complex utilizing CO2 + H2. Consequently, doubled growth rates, highest ATP formation rates and highest amounts of reduced products (ethanol, 2,3-butanediol) were observed when CO was the sole carbon and electron source.
sj-docx-1-jpc-10.1177_21501319231220742 – Supplemental material for Multistate Competing Risk Analysis of Transition Back to the Community Among Long-Term Care Home (LTC) Destined Patients: A Brief Report
Creators: name: Egbujie, Bonaventure A.
name: Tran, Jake
name: Hirdes, John P.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Health and Community Services
Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-1-jpc-10.1177_21501319231220742 for Multistate Competing Risk Analysis of Transition Back to the Community Among Long-Term Care Home (LTC) Destined Patients: A Brief Report by Bonaventure A. Egbujie, Jake Tran and John P. Hirdes in Journal of Primary Care & Community Health
Biosynthesis of antioxidative enzymes and polyphenolics content in calli cultures of Prunella vulgaris L. in response to auxins and cytokinins
Creators: name: Fazal, Hina
name: Abbasi, Bilal Haider
name: Ahmad, Nisar
name: Noureen, Bushra
name: Shah, Jahangir
name: Ma, Dan
name: Chuanliang, Liu
name: Akbar, Fazal
name: Uddin, Muhammad Nazir
name: Khan, Haji
name: Ali, Mohammad
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Prunella vulgaris L. is one of the therapeutic herbs containing various polyphenolics, which is used for multiple medicinal purposes. In this study, plant growth regulators (PGRs)-induced calli cultures from seed-derived leaf explants were exploited for the production of stress enzymes and polyphenolics. A growth curve was plotted for each PGR for 49 days period, which showed a distinct lag, log and decline phases. Here, the combination of naphthalene acetic acid (NAA) and 6-benzyleadenine (BA; 0.5 and 2.0 mg l−1) produced maximum fresh (6.32 FW-g/100 ml) and dry biomass (0.75 DW-g/100 ml) in contrast to control. The maximum synthesis of SOD (0.0154 FW-nM/min/mg) was detected on media comprising mixture of NAA and BA (1.5 mg l−1), while POD enzyme (0.366 FW-nM/min/mg) was higher at 0.5 mg l−1 NAA and 2, 4-dichlorophenoxy acetic acid. Further, NAA and BA (1.5 and 2.0 mg l−1) boosted up the synthesis of phenolics (18.83 GAE-mg/g-DW) and flavonoids content (18.05 RE-mg/g-DW) than control. Moreover, NAA of 1.0 and 2.0 mg l−1 were found supportive for maximum antioxidant activity (87.4%) and total protein (716 µg BSAE/mg-DW). This study will contribute in the development of cell culture in fermenter and synthesis of antioxidant secondary metabolites for commercial uses.
title: Kaffeehauskultur: Wien - Krakau - Paris
Creators: name: Löseke, Alina
Year: 2009

description: Kaffeehauskultur in Wien, Krakau un Paris ist das Thema dieser Arbeit. Viele einzelne Kaffeehäuser in den jeweiligen Städten wurden detailliert analysiert, auch Bilder wurden eingebunden, dienen als wichtiges Anschauungsmaterial und sind ein unverzichtbarer Teil der Arbeit. Das Hauptaugenmerk lag auf der Wiener und Krakauer Kaffeehauskultur, Paris wurde nur dann behandelt, wenn es als nützliches Vergleichsmaterial sinnvoll erschien. Der Wiener Kaffeehauskultur wurde besondere Aufmerksamketi geschenkt, weil ihre Einzigartigkeit und ihr Reichtum unvergleichlich sind.
Additional file 4 of Deep-learning-based radiomics of intratumoral and peritumoral MRI images to predict the pathological features of adjuvant radiotherapy in early-stage cervical squamous cell carcinoma
Creators: name: Zhang, Xue-Fang
name: Wu, Hong-yuan
name: Liang, Xu-Wei
name: Chen, Jia-Luo
name: Li, Jianpeng
name: Zhang, Shihao
name: Liu, Zhigang
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Neuroscience
Biotechnology
Mathematical Sciences not elsewhere classified
Cancer

description: Supplementary Material 4
sj-pdf-2-pch-10.1177_21501351231205804 - Supplemental material for Ventricular Assist Device Training and Emergency Management Among Pediatric Cardiac Intensive Care Physicians – Multicenter Cross-Sectional Survey
Creators: name: Esangbedo, Ivie D.
name: Yu, Priscilla
name: Choudhury, Tarif A.
name: Tume, Sebastian C.
name: Lasa, Javier J.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cardiology
Paediatrics
Surgery

description: Supplemental material, sj-pdf-2-pch-10.1177_21501351231205804 for Ventricular Assist Device Training and Emergency Management Among Pediatric Cardiac Intensive Care Physicians – Multicenter Cross-Sectional Survey by Ivie D. Esangbedo, Priscilla Yu, Tarif A. Choudhury, Sebastian C. Tume and Javier J. Lasa in World Journal for Pediatric and Congenital Heart Surgery
title: Religion and Communication Spaces
title: A Semio-pragmatic Approach
titleType: Other
Creators: name: Odin, Roger
Publisher: name: Karl-Franzens-Universität Graz
Year: 2015

description: Journal for Religion, Film and Media; Volume 2015 (1); Issue 1;
  Pages: 23-30; ISSN: 2414-0201
The Social Right Of Eu Citizens To Long-Term Care
Creators: name: Hans-Joachim Reinhard
Publisher: name: Zenodo
Year: 2018
Subjects: long-term care
social investment

description: The aim of this report is the identification of the regulatory and institutional gaps that promote or hinder the achievement of the objective to improve the provision of an acceptable level of care provision for the frail elderly, and the potential of SI in doing so.
c(RGDyk)-modified nanoparticles encapsulating quantum dots as a stable fluorescence probe for imaging-guided surgical resection of glioma under the auxiliary UTMD
Creators: name: Wu, Qi-Long
name: Xu, He-Lin
name: Xiong, Cui
name: Lan, Qing-Hua
name: Fang, Ming-Ling
name: Cai, Jin-Hua
name: Li, Hui
name: Zhu, Shu-Ting
name: Xu, Jing-Hong
name: Tao, Fang-Yi
name: Lu, Cui-Tao
name: Zhao, Ying-Zheng
name: Chen, Bin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Space Science
Medicine
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Marine Biology
Cancer

description: Surgical resection remains the preferred approach for some patients with glioblastoma (GBM), and eradication of the residual tumour niche after surgical resection is very helpful for prolonging patient survival. However, complete surgical resection of invasive GBM is difficult because of its ambiguous boundary. Herein, a novel targeting material, c(RGDyk)-poloxamer-188, was synthesized by modifying carboxyl-terminated poloxamer-188 with a glioma-targeting cyclopeptide, c(RGDyk). Quantum dots (QDs) as fluorescent probe were encapsulated into the self-assembled c(RGDyk)-poloxamer-188 polymer nanoparticles (NPs) to construct glioma-targeted QDs-c(RGDyk)NP for imaging-guided surgical resection of GBM. QDs-c(RGDyk)NP exhibited a moderate hydrodynamic diameter of 212.4 nm, a negative zeta potential of –10.1 mV and good stability. QDs-c(RGDyk)NP exhibited significantly lower toxicity against PC12 and C6 cells and HUVECs than free QDs. Moreover, in vitro cellular uptake experiments demonstrated that QDs-c(RGDyk)NP specifically targeted C6 cells, making them display strong fluorescence. Combined with ultrasound-targeted microbubble destruction (UTMD), QDs-c(RGDyk)NP specifically accumulated in glioma tissue in orthotropic tumour rats after intravenous administration, evidenced by ex vivo NIR fluorescence imaging of bulk brain and glioma tissue sections. Furthermore, fluorescence imaging with QDs-c(RGDyk)NP guided accurate surgical resection of glioma. Finally, the safety of QDs-c(RGDyk)NP was verified using pathological HE staining. In conclusion, QDs-c(RGDyk)NP may be a potential imaging probe for imaging-guided surgery.
Accelerometer-based fall detection using machine learning: training and testing on real-world falls
Creators: name: Palmerini, Luca
name: Klenk, Jochen
name: Becker, Clemens
name: Chiari, Lorenzo
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: fall detection
subject: wearable
subject: DDC 610 / Medicine & health
subject: DDC 620 / Engineering & allied operations
subject: Accelerometers
subject: Machine learning
subject: Smartphones
subject: Beschleunigungssensor
subject: Maschinelles Lernen
subject: Wearable Computing
subject: Handy

description: Falling is a significant health problem. Fall detection, to alert for medical attention, has been gaining increasing attention. Still, most of the existing studies use falls simulated in a laboratory environment to test the obtained performance. We analyzed the acceleration signals recorded by an inertial sensor on the lower back during 143 real-world falls (the most extensive collection to date) from the FARSEEING repository. Such data were obtained from continuous real-world monitoring of subjects with a moderate-to-high risk of falling. We designed and tested fall detection algorithms using features inspired by a multiphase fall model and a machine learning approach. The obtained results suggest that algorithms can learn effectively from features extracted from a multiphase fall model, consistently overperforming more conventional features. The most promising method (support vector machines and features from the multiphase fall model) obtained a sensitivity higher than 80%, a false alarm rate per hour of 0.56, and an F-measure of 64.6%. The reported results and methodologies represent an advancement of knowledge on real-world fall detection and suggest useful metrics for characterizing fall detection systems for real-world use.
Additional file 1 of Association of polymorphisms in the erythropoietin gene with diabetic retinopathy: a case–control study and systematic review with meta-analysis
Creators: name: Sesti, Luís Fernando Castagnino
name: Sbruzzi, Renan Cesar
name: Polina, Evelise Regina
name: dos Santos Soares, Douglas
name: Crispim, Daisy
name: Canani, Luís Henrique
name: dos Santos, Kátia Gonçalves
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1: Supplementary Table S1. Clinical and demographic profile of Brazilian T2DM patients. Supplementary Table S2 Genotype and allele distribution of EPO polymorphisms according to the period of inclusion in the study. Supplementary Table S3 Genotype and allele distribution of EPO polymorphisms according to the skin color/ethnicity. Supplementary Table S4 Haplotype frequencies of EPO polymorphisms according to the presence or absence of diabetic retinopathy (DR). Supplementary Table S5 Genotype, allele, and haplotype frequencies of EPO polymorphisms according to the presence or absence of diabetic macular edema (DME).
sj-docx-2-tag-10.1177_17562848231218555 – Supplemental material for Long-term outcomes of cyclosporin induction and ustekinumab maintenance combination therapy in patients with steroid-refractory acute severe ulcerative colitis
Creators: name: Vitali, Francesco
name: Rath, Timo
name: Klenske, Entcho
name: Vögele, Anna-Lena
name: Ganzleben, Ingo
name: Zundler, Sebastian
name: Strobel, Deike
name: Geppert, Carol
name: Hartmann, Arndt
name: Neurath, Markus F.
name: Atreya, Raja
Publisher: name: SAGE Journals
Year: 2023
Subjects: Nutrition and Dietetics not elsewhere classified
Oncology and Carcinogenesis not elsewhere classified
Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-2-tag-10.1177_17562848231218555 for Long-term outcomes of cyclosporin induction and ustekinumab maintenance combination therapy in patients with steroid-refractory acute severe ulcerative colitis by Francesco Vitali, Timo Rath, Entcho Klenske, Anna-Lena Vögele, Ingo Ganzleben, Sebastian Zundler, Deike Strobel, Carol Geppert, Arndt Hartmann, Markus F. Neurath and Raja Atreya in Therapeutic Advances in Gastroenterology
sj-docx-1-inq-10.1177_00469580231222334 – Supplemental material for Virtual Rehabilitation and COVID-19: Varied Adoption and Satisfaction Among Patients and Providers Participating in a Multi-Site Survey Study
Creators: name: Manes, Mindi R.
name: Burnfield, Judith M.
name: Boersma, Kelsey
name: Peoples, Jason
name: Davis, Anita
name: Beneciuk, Jason M.
name: Bialosky, Joel
name: Jordan, Katelyn
name: Osborne, Raine
Publisher: name: SAGE Journals
Year: 2024
Subjects: Nursing not elsewhere classified

description: Supplemental material, sj-docx-1-inq-10.1177_00469580231222334 for Virtual Rehabilitation and COVID-19: Varied Adoption and Satisfaction Among Patients and Providers Participating in a Multi-Site Survey Study by Mindi R. Manes, Judith M. Burnfield, Kelsey Boersma, Jason Peoples, Anita Davis, Jason M. Beneciuk, Joel Bialosky, Katelyn Jordan and Raine Osborne in INQUIRY: The Journal of Health Care Organization, Provision, and Financing
title: Methodological Challenges by (New) Media
title: An Essay on Perspectives and Possible Consequences
titleType: Other
Creators: name: Wessely, Christian
Publisher: name: Karl-Franzens-Universität Graz
Year: 2015

description: Journal for Religion, Film and Media; Volume 2015 (1); Issue 1;
  Pages: 37-42; ISSN: 2414-0201
Fiche d'inventaire - Objet n° KTM 19 - Clochette
Creators: name: École Française D'Extrême-Orient
name: Conservation D'Angkor
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Bronze

description: Source: FCA/3/2
description: IIIF manifest
description: created: 1950/1970
Preclinical evaluation of antigen-specific nanotherapy based on phosphatidylserine-liposomes for type 1 diabetes
Creators: name: Villalba, Adrian
name: Rodriguez-Fernandez, Silvia
name: Ampudia, Rosa-Maria
name: Cano-Sarabia, Mary
name: Perna-Barrull, David
name: Bertran-Cobo, Cesc
name: Ehrenberg, Clara
name: Maspoch, Daniel
name: Vives-Pi, Marta
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-producing cells. Due to the ability of apoptotic cells clearance to induce tolerance, we previously generated liposomes rich in phophatidylserine (PS) –a feature of apoptotic cells– loaded with insulin peptides to mimic apoptotic beta-cells. PS-liposomes arrested autoimmunity in experimental T1D through the induction of tolerance. The aim of this study was to investigate the potential of several peptides from different T1D autoantigens encapsulated in (PS)-liposomes for T1D prevention and to assess its safety. T1D autoantigens (Insulin, C-peptide, GAD65 and IA2) were encapsulated in PS-liposomes. Liposomes were administered to the 'gold-standard' model for the study of autoimmune T1D, the Non-Obese Diabetic mouse, that spontaneously develop the disease. Safety and toxicity of liposomes were also determined. Only PS-liposomes encapsulating insulin peptides decrease T1D incidence in the Non-Obese Diabetic mouse model. Disease prevention correlates with a decrease in the severity of the autoimmune islet destruction driven by leukocytes. PS-liposomes neither showed toxic effect nor secondary complications. Among the here referred autoantigens, insulin peptides are the best candidates to be encapsulated in liposomes, like an artificial apoptotic cell, for the arrest of autoimmunity in T1D in a safe manner.
Layered P2-NaxMn3/4Ni1/4O2 cathode materials for sodium-ion batteries : synthesis, electrochemistry and influence of ambient storage
Creators: name: Pfeiffer, Lukas Fridolin
name: Jobst, Nicola
name: Gauckler, Cornelius
name: Lindén, Mika
name: Marinaro, Mario
name: Passerini, Stefano
name: Wohlfahrt-Mehrens, Margret
name: Axmann, Peter
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Ambient storage
subject: Layered oxide
subject: DDC 540 / Chemistry & allied sciences
subject: Electrochemistry
subject: Electric batteries
subject: Sodium
subject: Cathodes
subject: Synthesis
subject: Elektrochemie
subject: Electric batteries
subject: Natrium
subject: Kathode
subject: Chemische Synthese

description: Sodium-ion batteries promise efficient, affordable and sustainable electrical energy storage that avoids critical raw materials such as lithium, cobalt and copper. In this work, a manganese-based, cobalt-free, layered NaxMn3/4Ni1/4O2 cathode active material for sodium-ion batteries is developed. A synthesis phase diagram was developed by varying the sodium content x and the calcination temperature. The calcination process towards a phase pure P2-Na2/3Mn3/4Ni1/4O2 material was investigated in detail using in-situ XRD and TGA-DSC-MS. The resulting material was characterized with ICP-OES, XRD and SEM. A stacking fault model to account for anisotropic broadening of (10l) reflexes in XRD is presented and discussed with respect to the synthesis process. In electrochemical half-cells, P2-Na2/3Mn3/4Ni1/4O2 delivers an attractive initial specific discharge capacity beyond 200 mAh g−1, when cycled between 4.3 and 1.5 V. The structural transformation during cycling was studied using operando XRD to gain deeper insights into the reaction mechanism. The influence of storage under humid conditions on the crystal structure, particle surface and electrochemistry was investigated using model experiments. Due to the broad scope of this work, raw material questions, fundamental investigations and industrially relevant production processes are addressed.
Additional file 1 of Contigs directed gene annotation (ConDiGA) for accurate protein sequence database construction in metaproteomics
Creators: name: Wu, Enhui
name: Mallawaarachchi, Vijini
name: Zhao, Jinzhi
name: Yang, Yi
name: Liu, Hebin
name: Wang, Xiaoqing
name: Shen, Chengpin
name: Lin, Yu
name: Qiao, Liang
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics

description: Additional file 1: Supplementary Table 1. The composition of the simulated communities with 12 species. Supplementary Table 2. Characteristics of the protein sequence databases derived from the metagenomic data of the synthetic microbial community. Supplementary Table 3. Details of the reference proteome of the 12 species. Supplementary Table 4. Characteristics of protein sequence databases derived from the metagenomic data of the stool sample. Supplementary Table 5. Characteristics of protein sequence databases derived from the in-silico mixed metagenomic data of the synthetic microbial community and the fecal sample. Supplementary Table 6. Abundance ranking of the 12 species in MD3-based protein sequence databases using the annotation tools of BLAST, Kaiju and Kraken2 from the in-silico mixed metagenomic data. Supplementary Table 7. LC gradient.