cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Recognition and repair of DNA damage by bacterial adenine glycosylases
Creators: name: Richards, Jody Lyn
Publisher: name: University of Utah
Year: 2012
Subjects: DNA repair
Adenine

description: E. coli MutY is a base excision repair (BER) glycosylase that excises adenine  mispaired opposite 7,8-dihydro-8-oxo-2'-deoxyguanine. MutY has helix-hairpin-helix  and Gly/Pro-Asp structural motifs characteristic of the BER glycosylase superfamily. In  addition, it has an iron-sulfur cluster that is critical for substrate binding and catalytic  activity. In the absence of DNA this cluster is not redox active; however, in the presence  of DNA, its redox potential shifts dramatically. Here, the effects of DNA binding on the  4Fe-4S cluster of MutY are analyzed by two spectroscopic methods: Electron  Paramagnetic Resonance (EPR) and X-ray Absorption Spectroscopy (XAS). By EPR, no  difference in levels of cluster oxidation is observed when MutY is bound to a DNA  oligonucleotide duplex containing either a G:C or G:THF central base pair, despite much  tighter binding of the latter. EPR also shows that oxidation of the cluster is affected by  the identity of the oxidant presented. XAS on MutY bound to DNA shows an increase in  covalency of the Fe-S bonds relative to the cluster in the absence of DNA.  MutY from a thermophilic bacterium B. stearothermophilus (BsMY) was expressed, purified, and characterized kinetically. Its glycosylase activity showed both temperature and salt dependence. In addition, BsMY discriminated more stringently than  E. coli MutY between OG:A and G:A substrates.
Neuroactivity of the naturally occurring aporphine alkaloid, roemerine
Creators: name: Bayazeid, Omer
name: Nemutlu, Emirhan
name: Eylem, Cemil Can
name: İlhan, Mert
name: Küpeli-Akkol, Esra
name: Karahan, Hande
name: Kelicen-Uğur, Pelin
name: Ersoz, Tayfun
name: Yalçın, Funda N.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Roemerine is a naturally occurring aporphine alkaloid. In this study, we screened a conformer library of Food and Drug Administration (FDA)-approved drugs to identify similar drugs that can assist in identifying the biological targets of roemerine. To assess the neuroactivity in vitro, we measured the levels of cell metabolites, Brain-Derived Neurotrophic Factor (BDNF) and serotonin (5-HT) in SH-SY5Y cell line. By means of structure-based virtual screening, we identified five drugs that are similar to roemerine; mirtazapine, atomoxetine, epinastine, diphenhydramine and orphenadrine. GC-MS metabolomics study revealed that roemerine has a high impact on alanine-aspartate-glutamate pathway in cell lysate and cultured medium. Additionally, roemerine increased intercellular 5-HT level and intracellular BDNF protein expression at 10 µM. In conclusion, roemerine — a major alkaloid in antidepressant-like effect possessing plants (P. lacerum and P. syriacum) — has a neuronal activity through increasing BDNF protein expression and affecting serotonergic and glutamatergic systems in SH-SY5Y cell line.
Additional file 1 of Cardiometabolic multimorbidity is associated with a worse Covid-19 prognosis than individual cardiometabolic risk factors: a multicentre retrospective study (CoViDiab II)
Creators: name: Maddaloni, Ernesto
name: D’Onofrio, Luca
name: Alessandri, Francesco
name: Mignogna, Carmen
name: Leto, Gaetano
name: Pascarella, Giuseppe
name: Mezzaroma, Ivano
name: Lichtner, Miriam
name: Pozzilli, Paolo
name: Agrò, Felice Eugenio
name: Rocco, Monica
name: Pugliese, Francesco
name: Lenzi, Andrea
name: Rury R. Holman
name: Mastroianni, Claudio Maria
name: Buzzetti, Raffaella
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 60506 Virology

description: Additional file 1:Table S1. SARS-CoV-2 infection symptoms at hospitalization in patients with, compared with those without, diabetes and in patients experiencing the primary composite compared with those without. Table S2. Odds ratio (OR) with [95% confidence intervals, CI] for secondary outcomes, unadjusted and adjusted for age and sex. Abbreviations: CV, cardiovascular; COPD, chronic obstructive pulmonary disease.
The use of brokered deposits and its relation to bank failure: the case of industrial banks
Creators: name: Reyes, Gustavo Adolfo
Publisher: name: University of Utah
Year: 2013
Subjects: Bank Failure
Brokered Deposits
Call Reports
FDIC
Industrial Banks
Moral Hazard

description: As a result of the Great Recession of 2007-2009, the financial services industry came under intense government scrutiny that resulted in the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010 (Dodd-Frank). As part of Dodd-Frank, the Federal Deposit Insurance Corporation (FDIC) was required to conduct a study on the use of brokered deposits and its effect on insurance premiums to be completed by July 2011. Across the banking sector, industrial banks are the primary users of brokered deposits and yet no industrial banks failed during the Great Recession. This thesis reviews the literature on industrial banks to help explain how this group of banks endured the effects of the Great Recession. A select data set from FDIC Call Reports will show how the existing regulation of brokered deposits provided the correct incentives to deter moral hazard issues that cause bank failures.
Eurysternus calligrammus Dalman 1824
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Eurysternus
Eurysternus calligrammus

description: § Eurysternus calligrammus Dalman, 1824
Eurysternus calligrammus Dalman 1824: 11 (Brazil)
Distribution. French Guiana: Gillet 1911b: 25; Blackwelder 1944: 197; Génier 2009: 106. Brazil: Dalman 1824: 11; Jessop 1985: 1105; Vaz-de-Mello 2000: 193 (as E. (Eurysternus) calligrammus); Génier 2009: 106.
Note. According to Génier (2009: 109), the record of Eurysternus calligrammus from French Guiana is probably due to a mislabeled specimen. We regard this species as not occurring in the research area.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on pages 85-86, DOI: 10.5281/zenodo.3678492
Brief an [Johann Friedrich Henkel]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1733

description: Schickt einen Brief nach; dass Dr. Cellarius da war und H. Sprechen wollte, u.a. kleine Nachrichten
description: von Friederika R. Henkelin
description: Briefanrede: "Lieber Papa"
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Coefficient of thermal expansion of Portland cement concrete in Utah and pavement performance
Creators: name: Rigby, Michael Thomas
Publisher: name: University of Utah
Year: 2012
Subjects: Cement--Thermal properties
Pavement

description: A laboratory investigation was conducted to determine the coefficient of thermal  expansion (CTE) of typical Utah Department of Transportation (UDOT) concrete  pavement mixtures made with aggregate obtained from 18 different sources around the  state of Utah. The predominant aggregate type used in the concrete mixtures included  quartzite, limestone, and basalt. The CTE of the concrete samples was determined using  the AASHTO standard T336-09 Coefficient of Thermal Expansion of Hydraulic Cement  Concrete. Three replicate test specimens were fabricated for each different aggregate  source. All concrete specimens met the requirements for UDOT (AA)AE-type mixture.  All specimens were moist-cured in a lime-bath for a minimum of 28 days after which  their compressive strength and CTE were measured. CTE testing was not conducted on  any specimens until they fulfilled the requirements set by the AASHTO standard T336-  09. The average CTE values for concrete containing quartzite aggregate is 5.63 |ie/0F and  ranging from 4.34 [xc/°F to 6.21 JIE/°F. The average CTE result for concrete containing  limestone aggregate is 4.67 |XE/°F and ranging from 4.26 jj,e/°F to 5.25 U£/°F. The average  CTE result for concrete containing basalt aggregate is 4.46 U£/°F and ranging from 4.17  |i£/°F to 4.74 |as/°F. Test results conclude that aggregate geology has a significant effect  on CTE results. In addition, this work also discusses the actual impact of the CTE  changes on the performance of jointed plain concrete pavements as measured by  transverse cracking, faulting, and international roughness index (IRI).
Brief an Graf [Hermann Karl von] Keyserling
Creators: name: Henkel, Johann Friedrich
Publisher: name: [s.n.]
Year: 1741

description: von [Johann Friedrich Henckel]
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Serologic classification of selected cases of myeloma
Creators: name: Allred, Lora
Publisher: name: University of Utah
Year: 2012
Subjects: Bone marrow - Tumors
Serodiagnosis

description: Serologic and electrophoretic procedures were employed in the study of serum and urinary proteins from twenty-six patients with multiple myeloma. Hematological, radiological and other findings associated with myelomatous disease, or otherwise applicable to interpretative analyses of serological data, were reviewed.  The serum and urinary proteins of these patients were found to have distinct electrophoretic properties and serologic characteristics.  In this series, the M-components of four patients were classified serologically as Gamma-A paraproteins, two as Gamma-D paraproteins, fifteen as Gamma-G paraproteins and five were nonreactive with the available class specific antisera. Antigenic typing of twenty of these proteins with light chain antisera gave a 1:1 ratio; that is, ten proteins reacted with lambda type light chain antisera and ten proteins reacted with kappa type antisera.  Considerable diversification was present in the electrophoretic patterns of the serum and urinary proteins.  The concentration of the electrophoretic fractions varied with the degree of proteinemia or proteinuria.  Hyperproteinemia was evident in only fifty per cent of the gammopathies included in this study.  The evidence of an abnormal component ranged from negligible to the appearance of three distinct peaks in an electrophoretic region where only one peak usually occurs. Quantitative estimation of an M component in the sera ranged from negligible to 8.8 gm/100 ml.  Proteinuria was demonstrated in the urine of eighteen of the twenty-three patients tested.  The immunoglobulins were quantitated by a radial immunodiffusion technique. A correlation was apparent with the light chain antigenic type and alterations of the Gamma-G immunoglobulin level in the Gamma-A and Gamma-D myelomas. Myeloma proteins consisting of lambda type light chains were associated with reduced Gamma-G serum levels, whereas myeloma proteins consisting of kappa type light chains were associated with quantitatively normal serum Gamma-G levels.
Eurysternus caribaeus
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Eurysternus
Eurysternus caribaeus

description: Eurysternus caribaeus (Herbst, 1789)
Scarabaeus caribaeus Herbst 1789: 300 (French Guiana - NEOTYPE)
= Eurysternus planus Dalman 1824: 10 (French Guiana)
= Eurysternus peruanus Harold 1875a: 137 (Peru)
Distribution. Guyana: Bodkin 1919: 213 (as E. planus); Forsyth and Gill 1993: 70; Génier 2009: 213; Bicknell et al. 2014: table S1; Boilly 2018: 39. Suriname: G. Halffter and V. Halffter 1977: 57; Génier 2009: 213; Larsen 2011: 98, 2013: 97; Boilly 2018: 39; MHCN; NZCS; RMNH. French Guiana: Dalman 1824: 10 (as E. planus); Harold 1880: 13; Gillet 1911b: 25; Balthasar 1941c: 340 (as E. peruanus); Blackwelder 1944: 197; G. Halffter and V. Halffter 1977: 57; Jessop 1985: 1102 (designation NEOTYPE Scarabaeus caribaeus); Feer 2000: 32; Feer and Pincebourde 2005: 30; Génier 2009: 213; Brûlé et al. 2011a: 193; Price and Feer 2012: 327; Boilly 2018: 39; MHCN; RMNH. Brazil (NA): Blackwelder 1944: 197; G. Halffter and V. Halffter 1977: 57; Jessop 1985: 1102; Vaz-de-Mello 2000: 193 (as E. (Eurysternus) caribaeus); Gardner et al. 2008: table S1 (NA); Génier 2009: 213 (NA); Ratcliffe 2013b: 493 (NA); Boilly 2018: 39 (NA). Venezuela (EO): Génier 2009: 213 (EO); Ferrer-Paris et al. 2013: 109 (EO); Boilly 2018: 39. “Amazon Basin”: Gillet 1911b: 25. Other: Herbst 1789: 300 (“Westindien” - as Scarabaeus caribaeus); Harold 1875a: 137 (Peru - as E. peruanus), 1880: 13 (Muzo [= Colombia]); Gillet 1911b: 25 (Colombia, Nicaragua - as E. caribaeus; Peru - as E. peruanus); Balthasar 1941c: 340 (Peru - as E. peruanus); Blackwelder 1944: 197 (Argentina, Colombia, Nicaragua - as E. caribaeus; Peru - as E. peruanus); G. Halffter and V. Halffter 1977: 57 (Argentina, Bolivia, Colombia, Ecuador, Honduras, Mexico, Nicaragua, Paraguay, Peru); Jessop 1985: 1102 (Colombia, Peru); Medina et al. 2001: 135 (Colombia); Noriega et al. 2007: 82 (Colombia); Génier 2009: 213 (Argentina, Belize, Bolivia, Colombia, Costa Rica, Ecuador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Trinidad and Tobago); Boilly 2018: 39 (Argentina, Belize, Bolivia, Colombia, Costa Rica, Ecuador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Trinidad and Tobago).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 86, DOI: 10.5281/zenodo.3678492
Tracking analysis of an improved infinite impulse
Creators: name: Flint, Randall S
Publisher: name: University of Utah
Year: 2012
Subjects: Adaptive filters
Adaptive signal processing

description: In mobile communication systems, the Doppler shift is a very common cause of time-varying changes in the carrier-frequency offset. This thesis discusses the use and design of an adaptive line enhancer to aid in the process of detecting  and tracking these time-varying changes. Specifically, it describes the use of an adaptive line enhancer in quadrature amplitude modulation (QAM), or phase shift keying (PSK), carrier-recovery systems. It shows that finite-impulse response (FIR)  adaptive line enhancers are not well-suited for tracking changes in the carrier frequency  offset, and that an infinite-impulse response (IIR) adaptive line enhancer is much more effective for this application. Then, based on the LMS algorithm, the IIR adaptive line enhancer algorithm is derived. Finally, an FIR filter is developed that is optimal for out-of-band noise rejection, and is used in conjunction with the  IIR adaptive line enhancer to further improve its line-enhancement capabilities. The FIR and IIR adaptive line enhancer algorithms are then simulated under typical mobile communication scenarios, to compare the effectiveness of each algorithm.  Then, it is shown that the IIR adaptive line enhancer, along with the optimal FIR  filter, is much more effective at tracking changes in the carrier-frequency offset.
Use-Cases Postdata Of The Domain Model
Creators: name: , Bermúdez-Sabel
name: Garrido Teixeira
name: Malta, Curado
Publisher: name: Zenodo
Year: 2018
Subjects: POSTDATA
Domain Model
Use-Cases
Validation
Metadata Application Profile
Semantic Web
Linked Open Data
European Poetry

description: This document is framed in the work of defining a domain model (or data model) for the European poetry. This work includes the study of the data structures of several databases of repertoires elected as representatives of the European Poetry. Some of these repertoires did not make available its data structure so the POSTADATA team analysed the correspondent graphical user interface (GUI) on the Web of Documents to understand its informational needs. The work also includes the study of a survey to final users of the data, and the construction of use-cases that use real data from resources available in five different repositories. See https://goo.gl/O0mqhI for more details about the repositories that are used to define the Domain Model.

This document presents the use-cases referred above.
Brief an [Christfried Kirch]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1730

description: von H[einrich] C[hristian] Hermitz
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Brief an Johann [I] Bernoulli
Creators: name: Hermann, Jacob
Publisher: name: [s.n.]
Year: 1702

description: von Jacobus Hermannus
description: Öffentliche Bibliothek der Universität Basel
description: Lateinisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
description: Autograph, siehe Signatur L Ia 659, Nr.1*
Brief an [Christfried] Kirch
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1727

description: von Joh[ann] Seb[astian] Heppe
description: Mit Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Brief an [Gottfried Kirch]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1692

description: von Christian Henzschel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Im Originalbrief ist lediglich der 22. Mai als Entstehungsdatum angegeben, im Zettelkatalog (Briefe UB Basel): "22.Mai [1.Juni] 1692"; unklar, welches Datum tatsächlich gemeint ist (10.11.2014/A100/bot)
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
description: Bl. 61: Figur betreffend ungewöhnliche Sonnenzeichen am 26. Febr. 92
Additional file 1 of Views of advanced cancer patients, families, and oncologists on initiating and engaging in advance care planning: a qualitative study
Creators: name: J. T. Toguri
name: L. Grant-Nunn
name: R. Urquhart
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Interview guide for patients and families of advanced cancer.
Eurysternus cayennensis Laporte 1840
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Eurysternus
Eurysternus cayennensis

description: Eurysternus cayennensis Laporte, 1840
Eurysternus cayennensis Laporte 1840: 93 (French Guiana - NEOTYPE)
= Eurysternus confusus Jessop 1985: 1106 (Ecuador) - Génier 2009: 25 (syn. nov.)
Distribution. Guyana: Bicknell et al. 2014: table S1. Suriname: Génier 2009: 25; Boilly 2018: 37; MHCN; RMNH. French Guiana: Laporte 1840: 93; Gillet 1911b: 25; Blackwelder 1944: 197; G. Halffter and V. Halffter 1977: 73; Jessop 1985: 1105 (designation NEOTYPE Eurysternus cayennensis); Feer 2000: 32; Feer and Pincebourde 2005: 30 (as E. cayennensis; as E. confusus); Génier 2009: 25; Brûlé and Dalens 2012b: 37; Price and Feer 2012: 327; Boilly 2018: 37; MHCN. Brazil (NA): Vaz-de-Mello 2000: 193 (as E. (Eurysternus) confusus); Gardner et al. 2008: table S1 (NA); Génier 2009: 25 (NA); Boilly 2018: 37. Venezuela (EO): G. Halffter and V. Halffter 1977: 73 (EO); Génier 2009: 25 (EO); Boilly 2018: 37. Other: Jessop 1985: 1106 (Colombia, Ecuador - as E. confusus); Medina et al. 2001: 135 (Colombia - as E. cayennensis; Colombia - as E. confusus); Génier 2009: 25 (Bolivia, Colombia, Ecuador, Peru); Boilly 2018: 37 (Colombia, Ecuador, Peru).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 86, DOI: 10.5281/zenodo.3678492
Caspicaiene: a new kaurene diterpene with anti-tubercular activity from an Aspergillus endophytic isolate in Gleditsia caspia desf
Creators: name: Moussa, Ashaimaa Y.
name: Sobhy, Hagar A.
name: Eldahshan, Omayma A.
name: Singab, Abdel Nasser B.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A new kaurene derivative with a new 6/6/6/5/6 ring system structure, given the trivial name caspicaiene, was isolated from the fungal culture of the Aspergillus N830 isolate identified by ITS region DNA sequencing. The compound was characterized by 1, 2 D NMR, and HR-ESI-MS-MS and revealed a promising anti-tubercular effect using the Alamar Blue Assay (MABA), in a dose dependent manner, with MIC value of 124.5 µM. Furthermore, six known compounds were isolated and showed significant MIC values against Mycobacterium tuberculosis, ranging between 15.63 µg/mL (26.5 µM) to 125 µg/mL (500 µM), compared to the positive control isoniazid whose MIC value was 0.24 µg/mL (1.75 µM), which sets them forth as potentially natural anti-tubercular agents. To gain further insight of the underlying mechanism, in-silico molecular docking, using the C-Docker protocol, was conducted and demonstrated various interactions between the isolated compounds and three key mycobacterial enzymes. Additionally, the cytotoxic activity was reported and showed the safety of these molecules according to the calculated safety index in the human hepatic cancer cell line (HepG2) and Vero cell lines.
Examination of how white adoptive parents racially socialize black/biracial adoptees
Creators: name: Smith, Darron
Publisher: name: University of Utah
Year: 2012
Subjects: Ethnic studies
Race and racism
White racial indentity development
Whiteness studies

description: This dissertation was concerned with the efforts of White adoptive parents to promote enculturation and racial inculcation processes by helping their adopted Black  children to develop a positive racial identity and strategies for effectively coping with racism. This dissertation study, drawing from transcripts of in-depth interviews, identified and analyzed themes in the lessons about race conveyed within families formed through  transracial adoption. The central aim of this dissertation was to examine how these race lessons connect family members to and perpetuate or challenge U.S. society?s existing racial hierarchy. In this study, I used the notion of White racial framing to move outside of the traditional arguments for or against transracial adoption and to explore how a close analysis of the adoptive parents? race lessons may serve as a learning tool for fostering  more inclusive and democratic forms of family, community, and teaching and learning processes.
Eurysternus cyclops Genier 2009
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Eurysternus
Eurysternus cyclops

description: Eurysternus cyclops Génier, 2009
Eurysternus cyclops Génier 2009: 237 (French Guiana)
Distribution. Suriname: Génier 2009: 237; Larsen 2011: 98, 2013: 97; Boilly 2018: 39; MHCN; NZCS; RMNH. French Guiana: Génier 2009: 237; Boilly 2018: 39. Brazil: Génier 2009: 237; Boilly 2018: 39.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 87, DOI: 10.5281/zenodo.3678492
Callypyrones from marine Callyspongiidae sponge Callyspongia diffusa: antihypertensive bis-γ-pyrone polypropionates attenuate angiotensin-converting enzyme
Creators: name: Chakraborty, Kajal
name: Francis, Prima
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry

description: Angiotensin I-converting enzyme (ACE) catalyses the biosynthesis of angiotensin II, a potent blood vessel constrictor, from angiotensin I, and ACE inhibitors were recognised as medications for hypertension. Undescribed bis-γ-pyrone polypropionate compounds, callypyrones A and B were purified from the organic extract of Callyspongiidae sponge species Callyspongia diffusa by repeated chromatographic purification. Callypyrone A exhibited significantly greater attenuation potential against ACE (IC50 0.48 mM) than that displayed by callypyrone B (IC50 0.57 mM) and showed comparable activity with standard ACE inhibitor captopril (IC50 0.36 mM). Higher electronic parameters of callypyrone A (topological surface area of 108.36) combined with balanced hydrophilic-lipophilic parameter (octanol–water coefficient, log Pow 1.9), as deduced from the structure–activity relationship analyses, could further indicate the improved ligand–receptor interactions resulting in its prospective ACE inhibitory activity. In silico docking analyses of the callypyrones with ACE recorded lowest binding energy (–12.58 kcal mol−1) for callypyrone A, which further supported the antihypertensive potential of the compound.
Schreiben für He[i]nrich Christian Hermitz
Creators: name: Hildesheim
Publisher: name: [s.n.]
Year: 1729

description: Privileg für den Druck eines Kalenders
description: Hildesheim in Curia ut súpra, Stadt, Regierung daselbst ; ... subscripsit et subsignavit Joh. Henning. Edeler Notarius publicus ...
description: Mit Stempel des Notars
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Brief an Christfried Kirch
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1727

description: von Joh[ann] Sebastian Heppe
description: Mit rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Brief an [Johann III] Bernoulli
Creators: name: Herbst, Johann Friedrich Wilhelm
Publisher: name: [s.n.]
Year: 1781

description: von [Johann] F[riedrich Wilhelm] Herbst
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Brief an [Johann III] Bernoulli
Creators: name: Henzi, Rudolf
Publisher: name: [s.n.]
Year: 1789

description: von R[udolf Samuel] Henzi
description: Mit gebrochenem rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Brief an [Johann III Bernoulli]
Creators: name: Henzi, Rudolf
Publisher: name: [s.n.]
Year: 1784

description: von R[udolf Samuel] Henzi
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Ligand interactions of the HIV-1 Gag p6 domain
Creators: name: Pornillos, Owen
Publisher: name: University of Utah
Year: 2012

description: The Gag protein of human immunodefleiency virus (HIV) contains a series of domains and motifs that drive virus assembly, package components of the virus, and recruit the cellular machinery required for formation of infectious virus particles. The C-terminal domain of Gag, termed p6, contains two short motifs that perform recruitment functions. A P(T/S)AP tetrapeptide motif binds the cellular protein TsglOl (tumor susceptibility gene 101) and is required for the release of new virus particles from the surface of infected cells, whereas an LXXLF motif binds the HIV-1 protein Vpr (viral protein R) and ensures its packaging into the assembling virion. To understand how p6 performs these recruitment functions, p6-Tsgl01 and p6-Vpr complexes were generated in vitro and characterized biochemically and structurally.  The N-terminal UEV domain of TsglOl, a ubiquitin E2 enzyme variant, binds directly to the p6 PTAP motif (Kd = 27±5 ^lM). NMR structural studies of TsglOl UEV, both free and in complex with a PTAP peptide derived from HIV-1 p6, revealed that it is structurally similar to E2 ubiquitin Ligase enzymes, but contains an extra N-terminal helix, an extended p-hairpin, and lacks two C-terminal heHces. The PTAP peptide occupies a hydrophobic groove on the TsglOl  UEV surface that is exposed by the absence of the C-terminal helices. The two PTAP prolines are bound by two pockets along the binding groove: one that recognizes the N-terminal Pro, and a second that recognizes the C-terminal Ala-Pro dipeptide. Interestingly, the Ala-Pro pocket uses the same mechanism of proline recognition as X-Pro pockets of SH3 and WW domains. Mutations in either PTAP or TsglOl UEV that reduce binding also reduce virus particle release. TsglOl is therefore an attractive target for the development of novel drugs against HIV.  TsglOl UEV also binds the protein ubiquitin, albeit weakly (Kd = 635±82 ^M), using the large concave surface of the p-sheet. Ubiquitin enhanced the affinity of p6 by 10-fold, consistent with a role for ubiquitin in modulating TsglOl UEV interactions.  Biochemical studies revealed that HIV-l p6 binds Vpr and a construct spanning the first 71 amino acids (Vpr 1-71) with similar affinity (Kd = -75 ^iM). Mutations in both Vpr and the p6 LXXLF motif that reduce Vpr packaging also reduce binding in vitro, and there is therefore good correlation between the biochemical and genetic data. Vpri-71 forms trimers and aggregates in solution, suggesting that self-association may facilitate Vpr virion incorporation by increasing its avidity to assembling Gag molecules at the plasma membrane. In summary, this thesis provides a biochemical and structural basis for understanding how the p6 domain of the HIV-l Gag protein recruits other proteins that function in viral replication and budding.
Brief an [Johann III] Bernoulli
Creators: name: Henzi, Rudolf
Publisher: name: [s.n.]
Year: 1789

description: von R[udolf Samuel] Henzi
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Evaluation of cytotoxic, immunomodulatory effects, antimicrobial activities and phytochemical constituents from various extracts of Passiflora edulis F. flavicarpa (Passifloraceae)
Creators: name: de Sousa, Georon Ferreira
name: do Nascimento Santos, Dayane Kelly Dias
name: da Silva, Ricardo Sérgio
name: da Silva Barros, Bárbara Rafaela
name: da Cruz-Filho, Iranildo José
name: de Azevedo Ramos, Bárbara
name: da Silva, Túlio Diego
name: da Silva, Pérsio Alexandre
name: de Lima-Neto, Reginaldo Gonçalves
name: de Gusmão, Norma Buarque
name: do Nascimento, Marcia Silva
name: de Melo, Cristiane Moutinho Lagos
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: The leaves of P. edulis were subjected to physicochemical analysis, such as ion content, extractives, and structural molecules. The hexanic, ethanolic and ethyl acetate extracts were submitted to phytochemical analyzes by GC-MS, HPLC-MS, and spectrophotometry. In addition, antioxidant (DPPH, ABTS and TAA methods) potential, antimicrobial (MIC method) action, cytotoxicity and immunostimulant activity (flow cytometry analysis) were performed. The extracts showed a moderate antioxidant capacity and revealed the presence of several metabolites, mainly phenols, such as caffeic acid, p-coumaric acid and luteolin. The ethyl acetate and ethanolic extracts showed antifungal activity. In addition, the extracts did not affect splenocytes viability at 12.5 μg/mL and promoted the production of IL-6, IL-10, IL-17 and TNF-α cytokines. P. edulis extracts showed antifungal and antioxidant activity and were able to induce immunostimulatory action in splenocyte cultures in vitro.
Brief an [Johann III Bernoulli]
Creators: name: Henzi, Rudolf
Publisher: name: [s.n.]
Year: 1788

description: von R[udolf Samuel] Henzi
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Therapeutic benefits of writing: a case study with abused women
Creators: name: Stevens, Margo
Publisher: name: University of Utah
Year: 2012

description: Evidence in favor of the use of writing for therapeutic purposes has been primarily anecdotal and impressionistic. Little empirical support was found for the potentialities of writing until benefits were revealed through research with college undergraduates. As a beginning effort, the present study examined the potential benefits and limitations of writing with a sample of women with clinically significant emotional problems. Analyses of three, 30-minute writings for 9 female subjects in treatment for issues related to domestic violence and results of a final interview provided evidence in favor of greater use of writing in clinical practice. Writing impacted three change agents positively (affective experiencing, cognitive mastery, and behavioral regulation), along with promotion of changes in self-concept and movement in the process of healing from trauma. The importance of the narrative perspective is emphasized. Limitations of the study and the need for future research are discussed.
Additional file 1 of The Impact of Pre-Exercise Carbohydrate Meal on the Effects of Yerba Mate Drink on Metabolism, Performance, and Antioxidant Status in Trained Male Cyclists
Creators: name: Krolikowski, Thaiana C.
name: Borszcz, Fernando K.
name: Panza, Vilma P.
name: Bevilacqua, Laura M.
name: Nichele, Sarah
name: da Silva, Edson L.
name: Amboni, Renata D. M. C.
name: Guglielmo, Luiz G. A.
name: Phillips, Stuart M.
name: de Lucas, Ricardo D.
name: Boaventura, Brunna C. B.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Physiological, perceptual, and performance variables assessed at different time points during CLT, TT, and sprints in the YMD-CHO, YMD-F, and Control-CHO conditions.
Doll play aggression in diabetic and non-diabetic children
Creators: name: Tenney, Janet Kathryn Gunzelman
Publisher: name: University of Utah
Year: 2012
Subjects: Aggression
Child Play

description: An illness such as diabetes may have numerous psychological implications, particularly to a child.  A young child with diabetes is not likely to comprehend all the ramifications of his illness.  He may not understand the importance of regulated diet and exercise, daily insulin injections, and urine testing.  Certain facets of the diabetic regimen may merely represent to him frustrating obstacles to his development.  It would seem logical that frustrations surrounding his illness could cause feelings of aggression and hostility within a diabetic child.  The purpose of the present study was to determine if a small number of diabetic children exhibited greater expressions of aggression during doll play than did an equal number of non-diabetic children.  The study was primarily descriptive in nature.  The doll play behavior of each diabetic and non-diabetic subject was analyzed for aggression according to a set of previously established criteria.  Comparisons were then made between the number of aggressive unites displayed by each diabetic child and that displayed by a non-diabetic child matched for age, sex, general position within the family, and approximate family income.  The data revealed no identifiable trends in regard to aggression.  The diabetic children in the sample did not exhibit consistently greater or fewer expressions of aggression than did the non-diabetic children in the sample.
Brief an [Johann III] Bernoulli
Creators: name: Henzi, Rudolf
Publisher: name: [s.n.]
Year: 1788

description: von R[udolf Samuel] Henzi
description: Mit rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Materials and devices for spintronics applications
Creators: name: Gray, Nathan Wheeler
Publisher: name: University of Utah
Year: 2015
Subjects: Magnetism
Rare earth oxide
Silicon
Spintronics
Thin films
Zinc oxide

description: Realization of next generation spintronic devices will require the use of design and engineering of new materials. In order to reach the performance requirements for spintronic transistor devices to become a reality, spin injection must be extremely efficient at room temperature. Understanding new materials and combinations of materials will enable the injection efficiency required for next-generation devices. Rare earth oxides are explored to determine the feasibility of doping magnetic elements to make new dilute magnetic dielectric materials for spin tunneling injection applications. Samarium Oxide (Sm2O3) doped with a small amount of cobalt (Co) is shown to exhibit a magnetic phenomenon which cannot be accounted for by conventional models. Though the observed magnetic properties appear quite similar to those observed in superparamagnetic systems, the origin of these properties is entirely different. A model, based on the widely accepted bound polaron theory for insulating ferromagnets, is proposed to explain the magnetic behavior of Co doped Sm2O3 films. We have also explored the growth and properties of high quality Tb2O3 thin films with on a variety of substrates in preparation for magnetic doping. We show enhanced dielectric constant related to improved crystal quality compared with previous reports, which makes this material of interest in high-k applications as well. Furthermore, we report room-temperature, all-electrical injection and detection of spin-polarized carriers in silicon using NiFe/MgO tunnel-barrier-contacts. From the magnetic-field dependence of the spin-accumulation voltage, spin-lifetime and diffusion-length of the carriers were determined to be 276 ps and 328 nm, respectively. Attaining spin diffusion lengths of >320 nm in Si channels is a ground breaking step and opens tremendous opportunities for integrating spin functionality into post-Moore-era electronic devices. We have carried out similar research with ZnO channels. We report all-electrical injection and detection of spin-polarized carriers in ZnO using NiFe/MgO tunnel-barrier-contacts. The three-terminal Hanle effect is used to study spin transport in single crystal thin film ZnO grown on sapphire. The results show that spin injection persists up to and above room temperature, with a measured lifetime τs=174 ps at 340K. These results underscore the importance of ZnO as a material for future active spintronics devices.
Degrowth in Postdigital Learning Design
Creators: name: Molloy, Kate
Publisher: name: National Teaching Repository
Year: 2024
Subjects: classificationCode: 390199
subject: Curriculum and pedagogy not elsewhere classified

description: The files available here are SCORM, HTML and PDF. This course is available for preview and access at: https://degrowth.kate-molloy.net/. 

This three-hour course is aimed at learning designers and other higher education professionals who regularly work with educational technology or support others to do so. The course will introduce the concept of degrowth in postdigital learning design, exploring better options for more convivial, sustainable learning experiences. 
In each of the sections below, there are readings and multimedia content, and each section has reflective activities to work through as you explore degrowth. You might consider how the questions apply in your own context, or more widely. It could also be worthwhile to pair up as you complete the course to discuss some of the more reflective elements. 

The course was created by Kate Molloy, when she was a part-time student in the MSc in Digital Education at the University of Edinburgh for the Digital Futures course. Kate has nearly twenty years of experience working in education and has spent eight years working to support digital teaching and learning in higher education. 

Course image "Tech that Grows" by Dheeraj Nanduri for ArtistsForClimate.org. Licensed under Creative Commons-Attribution-NonCommercial-ShareAlike 4.0 International license (CC-BY-NC-SA). 

Learning Design for Postdigital Futures © 2023 by Kate Molloy is licensed under CC -BY-NC 4.0 International
Brief an [Johann III] Bernoulli
Creators: name: Hennert, Johann Friedrich
Publisher: name: [s.n.]
Year: 1783

description: von J[ohann] F[riedrich] Hennert
description: Mit rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
description: Bl. 24-25: Über die Parabolisch. Laufbahn der Cometen und derselben wahren Anomala von J[ohann] F[riedrich] Hennert ([S.l., 1783])
Brief an [Johann III Bernoulli]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1785

description: Ueber den Tod von Dr. Wolf; eine Geldüberweisung
description: von [Fryderyk Ernest] Hennig
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
Novel design strategies to reduce the foreign body response to central nervous system implants
Creators: name: Skousen, John Lawrence
Publisher: name: University of Utah
Year: 2013
Subjects: Extracellular Matrix
Foreign Body Response
Inflammation
Macrophage
Microelectrode
Microglial

description: Multiple studies have shown the potential for using implantable microelectrode arrays to record consciously modulated neural signals and to restore volitional control of external devices to patients suffering from various nervous system and motor disorders. However, despite the promising potential of this technology, achieving widespread clinical application requires improving recording consistency and quality over a clinically relevant time frame. There is near consensus in the field that the foreign body response (FBR) that the brain mounts against implanted devices contributes to the observed recording instability. Available evidence suggests that pro-inflammatory and cytotoxic soluble factors secreted by reactive macrophages/microglia at the device-tissue interface mediate the cellular-level changes underlying the FBR. Based on this assumption, we hypothesize that implant designs that passively reduce the activation of these cells and the concentrations of their released soluble factors surrounding the implant will reduce the severity of the FBR. To explore this hypothesis we have studied the FBR to a series of novel test devices based on single-shank, Michigan-style microelectrode arrays. These devices have modified architectures and altered constitutive properties intended to reduce macrophage activation and/or the impact of their secreted factors. To facilitate the design and testing of these devices, we first created a series of three-dimensional (3-D) finite element simulations to predict the distributions of various macrophage-secreted factors around virtual device designs with altered architectures and permeability (Chapter 2). Building on predictions from these models, we have tested the efficacy of reducing the amount of device surface area presented for macrophage interaction/activation in altering the brain FBR (Chapter 3). Furthermore, we also examined the efficacy of increasing device permeability in altering the brain FBR by incorporating coatings that serve as cytokine sinks to passively absorb pro-inflammatory factors into the device and away from adjacent brain tissue (Chapter 4). In the final portion of this dissertation we move from these passive methods of limiting the extent and impact of activated inflammatory cells and describe the creation of extracellular matrix (ECM) based device coatings to bioactively reduce the FBR and drive improved healing and integration into tissue (Chapter 5).
Brief an [Johann III] Bernoulli
Creators: name: Hennert, Johann Friedrich
Publisher: name: [s.n.]
Year: 1782

description: von J[ohann] F[riedrich] Hennert
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Deutsch
description: Druck: Leipziger Magazin zur Naturkunde, Mathematik und Oekonomie. - Leipzig. - 1782, [S.] 171-172
description: Druck teilw.: Astronomisches Jahrbuch für das Jahr ... - Berlin : Lange. - [17]85, [S.] 228-229
description: Verzeichnung=Description=Inventaire Nov. 2014 HAN-Katalogisierungsregeln
description: Bl. 30-31: Erg. z. obig. Abh.+Fig.; in deutscher Sprache; Utrecht den 1 September 1782
Eurysternus hamaticollis Balthasar 1939
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Eurysternus
Eurysternus hamaticollis

description: Eurysternus hamaticollis Balthasar, 1939
Eurysternus hamaticollis Balthasar 1939d: 113 (French Guiana - LECTOTYPE)
Distribution. Guyana: Génier 2009: 240; Boilly 2018: 39. Suriname: Larsen 2011: 99, 2013: 97. French Guiana: Balthasar 1939d: 113; Blackwelder 1944: 197; Jessop 1985: 1101 (designation LECTOTYPE Eurysternus hamaticollis); Feer 2000: 32; Feer and Pincebourde 2005: 30; Génier 2009: 240; Brûlé et al. 2011a: 193; Price and Feer 2012: 327; Boilly 2018: 39; RMNH. Brazil (NA): Balthasar 1939d: 113; Blackwelder 1944: 197; Vaz-de-Mello 2000: 193 (as E. (Eurysternus) hamaticollis); Gardner et al. 2008: table S1 (NA); Génier 2009: 240 (NA); Boilly 2018: 39 (NA). Venezuela (EO): Génier 2009: 240 (EO); Ferrer-Paris et al. 2013: 109 (EO); Boilly 2018: 39. Other: Balthasar 1939d: 113 (Bolivia); Blackwelder 1944: 197 (Bolivia); Jessop 1985: 1101 (Bolivia); Medina et al. 2001: 135 (Colombia); Génier 2009: 240 (Bolivia, Colombia, Costa Rica, Ecuador, Peru); Boilly 2018: 39 (Bolivia, Colombia Costa Rica, Ecuador, Peru).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 87, DOI: 10.5281/zenodo.3678492