cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
WR 148: Identifying the companion of an extreme runaway massive binary
Creators: name: Munoz, Melissa
name: Moffat, Anthony F. J.
name: Hill, Grant M.
name: Shenar, Tomer
name: Richardson, Noel D.
name: Pablo, Herbert
name: St-Louis, Nicole
name: Ramiaramanantsoa, Tahina
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: WR 148 (HD 197406) is an extreme runaway system considered to be a potential candidate for a short-period (4.3173 d) rare WR + compact object binary. Provided with new high resolution, high signal-to-noise spectra from the Keck observatory, we determine the orbital parameters for both the primary WR and the secondary, yielding respective projected orbital velocity amplitudes of $88.1\pm3.8$ km s$^{-1}$ and $79.2\pm3.1$ km s$^{-1}$ and implying a mass ratio of $1.1\pm0.1$. We then apply the shift-and-add technique to disentangle the spectra and obtain spectra compatible with a WN7ha and an O4-6 star. Considering an orbital inclination of $\sim67^\circ$, derived from previous polarimetry observations, the system's total mass would be a mere 2-3 M$_{\odot}$ , an unprecedented result for a putative massive binary system. However, a system comprising a 37 M$_{\odot}$ secondary (typical mass of an O5V star) and a 33 M$_{\odot}$ primary (given the mass ratio) would infer an inclination of $\sim18^\circ$. We therefore reconsider the previous methods of deriving the orbital inclination based on time-dependent polarimetry and photometry. While the polarimetric results are inconclusive requiring better data, the photometric results favour low inclinations. Finally, we compute WR 148's space velocity and retrace the runaway's trajectory back to the Galactic plane (GP). With an ejection velocity of $198\pm27$ km s$^{-1}$ and a travel time of $4.7\pm0.8$ Myr to reach its current location, WR 148 was most likely ejected via dynamical interactions in a young cluster.
Additional file 1 of The B56γ3-containing protein phosphatase 2A attenuates p70S6K-mediated negative feedback loop to enhance AKT-facilitated epithelial-mesenchymal transition in colorectal cancer
Creators: name: Hsiao, Kai-Ching
name: Ruan, Siou-Ying
name: Chen, Shih-Min
name: Lai, Tai-Yu
name: Chan, Ren-Hao
name: Zhang, Yan-Ming
name: Chu, Chien-An
name: Cheng, Hung-Chi
name: Tsai, Hung-Wen
name: Tu, Yi-Fang
name: Law, Brian K.
name: Chang, Ting-Tsung
name: Chow, Nan-Haw
name: Chiang, Chi-Wu
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Additional file 1: Supplemental Table 1. List of antibodies applied in this study.
Materials to improve professional language skills for teachers in the new country: scenario ‘preparing your future as a teacher’
Creators: name: D’Herdt, Katrijn
name: Oruc Erturk, Nesrin
name: Holz, Oliver
name: Hachmeister, Silke
name: Hopton, Cherry
name: Petursdottir, Gudrun
Publisher: name: Univ. Bielefeld, Fakultät für Erziehungswissenschaft
Year: 2023
Subjects: subject: 370

description: The scenarios in this chapter will help international teachers to focus on both active and passive language skills, namely: speaking/writing and reading/listening by giving them possible scenarios which international teachers may come across in their daily teaching environments. All the documents consist of concrete materials. None of the materials provided include an evaluation or assessment, as the focus is on practicing. Furthermore, it is possible to work with the materials both face-to-face and in online situations. The first part of the scenarios was developed by the IQ Netzwerk from Germany and afterwards summarized and translated. In addition, three new scenarios have been developed within the ITTS project: ‘solving a conflict’, ‘reorientation of a student’, ‘preparing your future as a teacher’. The scenario on ‘preparing your future as a teacher’ can be found below.
Elastic scattering of vortex electrons provides direct access to the Coulomb phase
Creators: name: Ivanov, I. P.
name: Seipt, D.
name: Surzhykov, A.
name: Fritzsche, S.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Vortex electron beams are freely propagating electron waves carrying adjustable orbital angular momentum with respect to the propagation direction. Such beams were experimentally realized just a few years ago and are now used to probe various electromagnetic processes. So far, these experiments used the single vortex electron beams, either propagating in external fields or impacting a target. Here, we investigate the elastic scattering of two such aligned vortex electron beams and demonstrate that this process allows one to experimentally measure features which are impossible to detect in the usual plane-wave scattering. The scattering amplitude of this process is well approximated by two plane-wave scattering amplitudes with different momentum transfers, which interfere and give direct experimental access to the Coulomb phase. This phase (shift) affects the scattering of all charged particles and has thus received significant theoretical attention but was never probed experimentally. We show that a properly defined azimuthal asymmetry, which has no counterpart in plane-wave scattering, allows one to directly measure the Coulomb phase as function of the scattering angle.
description: 23 pages, 6 figures
Anticorrelated position fluctuation of lipids in forming membrane water pores: molecular dynamics simulations study with dengue virus capsid protein
Creators: name: Rajapaksha, Suneth P.
name: Nawagamuwage, Sithara U.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: Computational Biology

description: The traffic of molecules into or out of cells is regulated by many membrane-associated mechanisms. Membrane pores are considered as one of the major passage mechanisms, although molecular-level understanding of pore formation is still vague. The opening of a membrane pore depends on many factors, including the influence of some proteins. The ability of the cell-penetrating peptides and supercharged proteins to form membrane pores has been reported. We studied pore formation through dipalmitoylphosphatidylcholine (DPPC) lipid bilayers by supercharged dengue virus capsid (C) protein. Atomistic molecular dynamics simulations confirmed the formation of membrane pores by a combined effect of the C protein and the membrane electric field. Analyses of simulated trajectories showed highly correlated vertical position fluctuations between the Cα atom of the membrane-anchored arginine residues and the phosphorus atoms of the surrounding DPPC lipids. Certain regions of the bilayer were negatively correlated while the others were positively correlated with respect to the fluctuations of the Cα atom of the anchored arginine residues. When positively correlated lipids in one leaflet vertically aligned with the negatively correlated lipids in the other leaflet, a local anticorrelated region was generated by weakening the bilayer. The membrane pore was always formed close to this anticorrelated region. Once formed, the C protein followed the hydrated pathway provided by the water-filled pores to cross the membrane. Communicated by Ramaswamy H. Sarma
An investigation of flow components in separate sewerage systems
Creators: name: Norrish, A. M. .
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Xenia kuekenthali Roxas 1933
Creators: name: Halász, Anna
name: Mcfadden, Catherine S.
name: Toonen, Robert
name: Benayahu, Yehuda
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Cnidaria
Anthozoa
Alcyonacea
Xeniidae
Xenia
Xenia kuekenthali

description: Xenia kuekenthali Roxas, 1933
Xenia kuekenthali Roxas, 1933: 79–80, plate 1, Fig. 1; Xenia kuekenthali; Utinomi 1950: 84, Fig. 2 d–g, 3a; Verseveldt & Cohen 1971: 61, table 1; Benayahu 1990: 114, table 1, listed only; Reinicke 1997: 31–32, plate 11.
Material. Holotype and two small fragments: ZMB 6917, Philippines, Mindoro, Puerto Galera, Sabang, 1912– 1914, coll. members of the Zoology Department, University of the Philippines.
Description. The holotype is 45–50 mm high; its stalk is 13–15 mm long and splits at the base into five branches, four of which split again into two, 13–15 mm above the colony base; the latter branches are 10–14 mm long, 7–8 mm wide at their base, 4–5 mm at their uppermost part. The colony stalk is 45 mm wide at its widest part. The holotype is extremely flabby. The polyp body is up to 4 mm long, and the tentacles up to 4 mm long, featuring one row of pinnules on each side, with 8–10 pinnules. The pinnules are extremely short, up to 0.10 mm long and 0.30 mm wide, with no gap between adjacent ones. No sclerites are found in any part of the colony. The ethanolpreserved colony is light beige. The two fragments have similar features to those of the holotype.
Remarks. The original description of X. kuekenthali by Roxas (1933) indicated two rows of pinnules with 8 pinnules in a row, thus not corresponding to the current findings of one row of pinnules. Utinomi (1950) referred to a specimen from Japan as having two rows with 10–12 pinnules in the outermost row. Later, Benayahu (1990) reported this species from the Red Sea based on the original description. Reinicke (1997) described a pulsating colony of the species from the Gulf of Aqaba, and indicated that the validation of its presence in the Red Sea should be based on the examination of additional material. The current examination of the type of Xenia kuekenthali revealed that the original description was inaccurate, and thus most probably led to the recurring errors in the subsequent studies.
Similar species and conclusion. X. kuekenthali is the only Xenia species among those examined in this study with one row of pinnules.
Distribution. Philippines.
description: Published as part of Halász, Anna, Mcfadden, Catherine S., Toonen, Robert & Benayahu, Yehuda, 2019, Re-description of type material of Xenia Lamarck, 1816 (Octocorallia: Xeniidae), pp. 201-239 in Zootaxa 4652 (2) on pages 215-216, DOI: 10.11646/zootaxa.4652.2.1, http://zenodo.org/record/3363653
(Mis)using Global Vaccine Inequality: An Analysis of the Global Political Economy of Bilateral COVID-19 Vaccine Donations
Creators: name: Ras, Niels
Publisher: name: University of Chicago
Year: 2022
Subjects: subject: COVID-19
subject: vaccines
subject: political economy
subject: vaccine diplomacy
subject: global inequality
subject: vaccine donations
subject: determinants
subject: foreign aid
subject: foreign policy
subject: international relations
subject: bilateralism
subject: COVAX
subject: China
subject: United States
subject: India

description: The global inequality in vaccines has led countries with an abundance of vaccines to donate vaccines to countries in need. These vaccine donations were not only provided out of pure altruism but were part of vaccine diplomacy. This thesis finds through descriptive case studies and quantitative research that political factors were often more important than factors of need in the determination of who to donate vaccines to. For China, political alignment was an important factor, just as GDP per capita, Taiwan relations, whether they are part of the Belt and Road Initiative, and geographical distance. For the United States, the pre-existing trade relations and whether a country is democratic were important. And India primarily donated to countries that politically align with them, are democratic, support Taiwan, and have a large Indian diaspora. These findings extend the literature on bilateral foreign aid and provides a better understanding of the global political economy of vaccine donations. Overall, the conclusion is that, even though vaccine donations have helped countries in need significantly, it was primarily an extension of the donor countries’ foreign policy.
Quantum-enhanced machine learning
Creators: name: Dunjko, Vedran
name: Taylor, Jacob M.
name: Briegel, Hans J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The emerging field of quantum machine learning has the potential to substantially aid in the problems and scope of artificial intelligence. This is only enhanced by recent successes in the field of classical machine learning. In this work we propose an approach for the systematic treatment of machine learning, from the perspective of quantum information. Our approach is general and covers all three main branches of machine learning: supervised, unsupervised and reinforcement learning. While quantum improvements in supervised and unsupervised learning have been reported, reinforcement learning has received much less attention. Within our approach, we tackle the problem of quantum enhancements in reinforcement learning as well, and propose a systematic scheme for providing improvements. As an example, we show that quadratic improvements in learning efficiency, and exponential improvements in performance over limited time periods, can be obtained for a broad class of learning problems.
description: 5+15 pages. This paper builds upon and mostly supersedes arXiv:1507.08482. In addition to results provided in this previous work, here we achieve learning improvements in more general environments, and provide connections to other work in quantum machine learning. Explicit constructions of oracularized environments given in arXiv:1507.08482 are omitted in this version
Sparticles in Motion - getting to the line in compressed scenarios with the Recursive Jigsaw Reconstruction
Creators: name: Jackson, Paul
name: Rogan, Christopher
name: Santoni, Marco
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The observation of light super-partners from a supersymmetric extension to the Standard Model is an intensely sought-after experimental outcome, providing an explanation for the stabilization of the electroweak scale and indicating the existence of new particles which could be consistent with dark matter phenomenology. For compressed scenarios, where sparticle spectra mass-splittings are small and decay products carry low momenta, dedicated techniques are required in all searches for supersymmetry. In this paper we suggest an approach for these analyses based on the concept of Recursive Jigsaw Reconstruction, decomposing each event into a basis of complementary observables, for cases where strong initial state radiation has sufficient transverse momentum to elicit the recoil of any final state sparticles. We introduce a collection of kinematic observables which can be used to probe compressed scenarios, in particular exploiting the correlation between missing momentum and that of radiative jets. As an example, we study squark and gluino production, focusing on mass-splittings between parent super-particles and their lightest decay products between 25 and 200 GeV, in hadronic final states where there is an ambiguity in the provenance of reconstructed jets.
FINANCIAL PERFORMANCE ANALYSIS OF KPR MILL LIMITED
Creators: name: Dr. N. Prem Anand*, S. Nikila** & D. Abishek**
Publisher: name: Zenodo
Year: 2025

description: This research paper analyzes the financial performance of KPR Mill Limited for five years from 2019-2020 to 2023-2024 using key financial ratios and trend analysis. The research examines the company’s liquidity, solvency, profitability, and operational efficiency through ratio analysis. Secondary data from published financial statements were analyzed using tools such as the current ratio, quick ratio, debt-equity ratio, inventory turnover, and profit margins. The findings indicate overall financial stability with strong equity growth and liquidity, though some fluctuations in inventory and asset utilization suggest areas for improvement. The research offers insights to support informed decision-making for stakeholders and investors.
Central Engine of Late-Time X-ray Flares with Internal Origin
Creators: name: Mu, Hui-Jun
name: Gu, Wei-Min
name: Hou, Shu-Jin
name: Liu, Tong
name: Lin, Da-Bin
name: Yi, Tuan
name: Liang, En-Wei
name: Lu, Ju-Fu
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: This work focuses on a sample of seven extremely late-time X-ray flares with peak time $t_{\rm p} > 10^4 {\rm s}$, among which two flares can be confirmed as the late-time activity of central engine. The main purpose is to investigate the mechanism of such late-time flares based on the internal origin assumption. In the hyper-accreting black hole (BH) scenario, we study the possibility of two well-known mechanisms as the central engine to power such X-ray flares, i.e., the neutrino-antineutrino annihilation and the Blandford-Znajek (BZ) process. Our results show that the annihilation luminosity is far below the observational data. Thus, the annihilation mechanism cannot account for such late-time flares. For the BZ process, if the role of outflows is taken into consideration, the inflow mass rate near the horizon will be quite low such that the magnetic field will probably be too weak to power the observed X-ray flares. We therefore argue that, for the late-time flares with internal origin, the central engine is unlikely to be associated with BHs. On the contrary, a fast rotating neutron star with strong bipolar magnetic fields may be responsible for such flares.
description: 16 pages, 6 figures, accepted for publication in ApJ
Drug repositioning to propose alternative modulators for glucocorticoid receptor through structure-based virtual screening
Creators: name: Metin, Reyhan
name: Akten, Ebru Demet
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Drug repositioning has recently become one of the widely used drug design approaches in proposing alternative compounds with potentially fewer side effects. In this study, structure-based pharmacophore modelling and docking was used to screen existing drug molecules to bring forward potential modulators for ligand-binding domain of human glucocorticoid receptor (hGR). There exist several drug molecules targeting hGR, yet their apparent side effects still persist. Our goal was to disclose new compounds via screening existing drug compounds to bring forward fast and explicit solutions. The so-called shared pharmacophore model was created using the most persistent pharmacophore features shared by several crystal structures of the receptor. The shared model was first used to screen a small database of 75 agonists and 300 antagonists/decoys, and exhibited a successful outcome in its ability to distinguish agonists from antagonists/decoys. Then, it was used to screen a database of over 5000 molecules composed of FDA-approved, worldwide used and investigational drug compounds. A total of 110 compounds satisfying the pharmacophore requirements were subjected to different docking experiments for further assessment of their binding ability. In the final hit list of 54 compounds which fulfilled all scoring criteria, 19 of them were nonsteroidal and when further investigated, each presented a unique scaffold with little structural resemblance to any known nonsteroidal GR modulators. Independent 100 ns long MD simulations conducted on three selected drug candidates in complex with hGR displayed stable conformations incorporating several hydrogen bonds common to all three compounds and the reference molecule dexamethasone. Communicated by Ramaswamy H. Sarma
Grant proposal: Invest in Open Infrastructure operational capacity
Creators: name: Thaney, Kaitlin
Publisher: name: Zenodo
Year: 2021
Subjects: grant proposals
scholarly communication
open science
open infrastructure

description: Grant proposal submitted by Invest in Open Infrastructure to Arcadia, a charitable fund of Lisbet Rausing and Peter Baldwin, in 2023-01. From the proposal summary: "...We are asking the Arcadia Fund for three-years of support to scale the operational capacity of IOI. Additional staff and resources will accelerate our efforts to alleviate decision fatigue at institutions and meet information gaps with cutting-edge research, analysis, and guidance. Based on our research, we believe that coordinated action is critical today in order to drive investment to where it’s needed most to advance open infrastructure, and improve the health of the ecosystem writ large."
Control of an airmotor powered servodrive via a set of computer-controlled on-off valves
Creators: name: Sen-Ngam., Smarn
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Forschende Lehre in einer polarisierten Gesellschaft
Creators: name: Domann, Valentin
name: Liebscher, Stephan
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: forschende Lehre
subject: Urban Transition Lab
subject: Aktionsforschung
subject: Solidarität
subject: Rechtspopulismus
subject: Geographie
subject: 370 Bildung und Erziehung

description: Der Artikel geht der Frage nach, wie geographische Lehre an der Hochschule in Zeiten eines allgegenwärtigen Rechtsrucks kritische Perspektiven anregen und zugleich in stadtgesellschaftlichen Polarisierungsprozessen emanzipatorisch intervenieren kann. Hierfür werden Erfahrungen aus zwei Lehrforschungsprojekten aus Chemnitz und Berlin dialogisch reflektiert. Dabei werden Potenziale von verschiedenen Ansätzen der geographischen Forschung und Lehre, die sich partizipatorischen und transformativen Method(ologi)en bedienen, wie Aktionsforschung und Urban Transition Lab, diskutiert.
Pontential energies and potential-energy tensors for subsystems: general properties
Creators: name: Caimmi, R.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: With regard to generic two-component systems, the theory of first variations of global quantities is reviewed and explicit expressions are inferred for subsystem potential energies and potential-energy tensors. Performing a conceptual experiment, a physical interpretation of subsystem potential energies and potential-energy tensors is discussed. Subsystem tidal radii are defined by requiring an unbound component in absence of the other one. To this respect, a few guidance examples are presented as: (i) an embedding and an embedded homogeneous sphere; (ii) an embedding and an embedded truncated, singular isothermal sphere where related centres are sufficiently distant; (iii) a homogeneous sphere and a Roche system i.e. a mass point surrounded by a vanishing atmosphere. The results are discussed and compared with the findings of earlier investigations.
description: MS of 39 pages, 2 tables, 3 figures
Additional file 1 of Health-related quality of life of mothers and developmental characteristics of very low birth weight children at 2.5 years of age: results from the Japan Environment and Children’s Study (JECS)
Creators: name: Sasaki, Hatoko
name: Pak, Kyongsun
name: Mezawa, Hidetoshi
name: Yamamoto-Hanada, Kiwako
name: Ishitsuka, Kazue
name: Konishi, Mizuho
name: Nishizato, Minaho
name: Sato, Miori
name: Saito-Abe, Mayako
name: Yang, Limin
name: Ohya, Yukihiro
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1: Supplementary Table 1. Summary of Categorical J-ASQ - Percentile Method (N = 357)
title: Compiling Measurement Invariant Short Scales in Cross‐Cultural Personality Assessment Using Ant Colony Optimization
Creators: name: Jankowsky, Kristin
name: Olaru, Gabriel
name: Schroeders, Ulrich
Publisher: name: Universität Kassel
Year: 2020
Subjects: subject: ant colony optimization
subject: item selection
subject: short scale construction
subject: measurement invariance
subject: personality assessment
subject: 150
subject: Persönlichkeitsforschung
subject: Kulturvergleich
subject: Ameisenalgorithmus
subject: Persönlichkeitsbeurteilung

description: This article earned Open Materials badge through Open Practices Disclosure from the Center for Open Science: https://osf.io/tvyxz/wiki. The materials are permanently and openly accessible at: https://osf.io/ds7j5/. Author's disclosure form may also be found at the Supporting Information in the online version.
description: Gefördert im Rahmen des Projekts DEAL
New Photometrically Variable Magnetic Chemically Peculiar Stars in the ASAS-3 Archive
Creators: name: Hümmerich, Stefan
name: Paunzen, Ernst
name: Bernhard, Klaus
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The magnetic Ap or CP2 stars are natural atomic and magnetic laboratories and ideal testing grounds for the evaluation of model atmospheres. CP2 stars exhibiting photometric variability are traditionally referred to as alpha2 Canum Venaticorum (ACV) variables. Strictly periodic changes are observed in the spectra and brightness of these stars, which allow the derivation of rotational periods. Related to this group of objects are the He-weak (CP4) and He-rich stars, some of which are also known to undergo brightness changes due to rotational modulation. Increasing the sample size of known rotational periods among CP2/4 stars is an important task, which will contribute to our understanding of these objects and their evolution in time. We have compiled an extensive target list of magnetic chemically peculiar (CP2/4) stars. In addition to that, a systematic investigation of early-type (spectral types B/A) variable stars of undetermined type in the International Variable Star Index of the AAVSO (VSX) yielded additional ACV candidates, which were included in our sample. We investigated our sample stars using publicly available observations from the ASAS-3 archive. We were able to identify another 360 stars exhibiting photometric variability in the accuracy limit of the ASAS-3 data, thereby concluding our search for photometrically variable magnetic chemically peculiar stars in the ASAS-3 archive. Summary data, folded light curves and, if available, information from the literature are presented for all variable stars of our sample, which is composed of 334 bona-fide ACV variables, 23 ACV candidates and three eclipsing binary systems. In particular, we call attention to HD 66051 (V414 Pup), which was identified as an eclipsing binary system showing obvious rotational modulation of the light curve due to the presence of an ACV variable in the system.
description: 22 pages, 8 figures
Additional file 2 of The B56γ3-containing protein phosphatase 2A attenuates p70S6K-mediated negative feedback loop to enhance AKT-facilitated epithelial-mesenchymal transition in colorectal cancer
Creators: name: Hsiao, Kai-Ching
name: Ruan, Siou-Ying
name: Chen, Shih-Min
name: Lai, Tai-Yu
name: Chan, Ren-Hao
name: Zhang, Yan-Ming
name: Chu, Chien-An
name: Cheng, Hung-Chi
name: Tsai, Hung-Wen
name: Tu, Yi-Fang
name: Law, Brian K.
name: Chang, Ting-Tsung
name: Chow, Nan-Haw
name: Chiang, Chi-Wu
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Additional file 2: Supplementary Fig. 1. B56γ3 enhances Akt phosphorylation at both Thr308 and Ser473. Supplementary Fig. 2. The PP2A-B56γ3 holoenzyme physically interacts with p70S6K. Supplementary Fig. 3. The PP2A-B56γ3 holoenzyme catalyzes dephosphorylation of phospho-p70S6Kin vitro. Supplementary Fig. 4. B56γ3 downregulates p70S6K activation in response to insulin stimulation and supply of amino acids in NIH3T3 cells. Supplementary Fig. 5. B56γ3 upregulates AKT activation through downregulating p70S6K-mediated negative feedback loop regulation on growth factor signaling. Supplementary Fig. 6. B56 3 promotes wound healing migration in CRC cells. Supplementary Fig. 7. PPP2R5C knockout clones of HCT116 cells showed reduced mesenchymal phenotypes. Supplementary Fig. 8. B56 3 promotes EMT hallmarks in CRC cells through enhancing AKT activation. Supplementary Fig. 9. Knockdown of B56γ3 decreases phosphorylation of GSK3β at Ser9 in CRC cells. Supplementary Fig. 10. High expression of B56γ3 associates with poor prognosis in adrenocortical carcinoma, esophageal carcinoma, uveal melanoma, and kidney chromophobe carcinoma. Supplementary Fig. 11. The upregulation of AKT phosphorylation by reexpression of B56γ3 in a PPP2R5C knockout clone of HCT116 cells occurred at 48 h after B56γ3 re-expression.
Dynamics of expansion of the Universe in the models with non-minimally coupled dark energy
Creators: name: Neomenko, R.
name: Novosyadlyj, B.
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences
subject: J.2
subject: 85-00

description: We consider the dark energy model with barotropic equation of state, which interacts with dark matter through gravitation and another force, causing the energy-momentum exchange between them. Both components are described in approximation of ideal fluids, which are parametrized by density and equation of state parameters. Three types of interactions between dark components are considered: the interaction independent from their densities, the one proportional to density of dark energy and the one proportional to density of dark matter. The equations which describe the expansion dynamics of homogeneous and isotropic Universe and evolution of densities of both components for different values of interaction parameter are obtained on the bases of the general covariant conservation equations and Einstein's ones. For three kinds of interactions we show the existence of the range of values of parameters of dark energy for which the densities of dark components and their sum are negative. We find the conditions of positivity of density of dark energy and dark matter. The constraints on the value of parameter of interaction are derived. The dynamics of expansion of the Universe with these interactions of dark energy and dark matter is analysed.
description: 18 pages, 6 figures, published in Kinematics and Physics of Celestial Bodies (2016)
Performance evaluation of the A.P.P.M. Wesley Vale cold soda eucalypt prex impregnator
Creators: name: Cain, Peter M.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Role of Experiments in the Progress of Science: Lessons from our History
Creators: name: Roy, D. P.
Publisher: name: arXiv
Year: 2016
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: I shall discuss the history of Indian astronomy, Aurveda (life science), chemistry and metallurgy to illustrate how downgrading experiments from scientific learning lead to the decline of ancient Indian science and civilization. We shall see that in the glorious period of ancient Indian civilization, lasting up to the 9th century, there was close interaction between experimental investigations and theoretical analyses in each of these sciences. This was further augmented by two-way interactions with the other advanced civilizations of that time. But both these interactions came to an end around 9th century, leading to the stagnation and decline of Indian science and civilization over the next thousand years. This was the cause rather than the consequence of its subjugation by external invaders, though it was no doubt aggravated by the latter.
description: 20 pages with 7 figures
Bakterie siarkowe zasiedlające czarny łupek Kupferschiefer i ich znaczenie w przemianach nieorganicznych zredukowanych związków siarki
Creators: name: Matlakowska, Renata
name: Piotrowska, Wioletta
Publisher: name: Wydział Geoinżynierii, Górnictwa i Geologii, Politechnika Wrocławska, Wrocław / Faculty of Geoengineering, Mining and Geology, Wrocław University of Science and Technology, Wrocław
Year: 2018

description: Łupek miedzionośny IV, Ratajczak T., Drzymała J. (red.), WGGG PWr, Wrocław, ISBN 978-83-946706-7-2
Charakterystyka i właściwości kerogenu w kontekście wzbogacania rud miedzi
Creators: name: Kibort, Katarzyna
name: Małachowska, Aleksandra
Publisher: name: Wydział Geoinżynierii, Górnictwa i Geologii, Politechnika Wrocławska, Wrocław / Faculty of Geoengineering, Mining and Geology, Wrocław University of Science and Technology, Wrocław
Year: 2018

description: Łupek miedzionośny IV, Ratajczak T., Drzymała J. (red.), WGGG PWr, Wrocław, ISBN 978-83-946706-7-2
Dynamical Stationarity as a Result of Sustained Random Growth
Creators: name: Biró, Tamás
name: Néda, Zoltán
Publisher: name: arXiv
Year: 2016
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Mathematical Finance (q-fin.MF)
subject: FOS: Physical sciences
subject: FOS: Economics and business

description: In sustained growth with random dynamics stationary distributions can exist without detailed balance. This suggests thermodynamical behavior in fast growing complex systems. In order to model such phenomena we apply both a discrete and a continuous master equation. The derivation of elementary rates from known stationary distributions is a generalization of the fluctuation--dissipation theorem. Entropic distance evolution is given for such systems. We reconstruct distributions obtained for growing networks, particle production, scientific citations and income distribution.
description: 7 pages, 2 Figures, PRE style
Additional file 2 of Health-related quality of life of mothers and developmental characteristics of very low birth weight children at 2.5 years of age: results from the Japan Environment and Children’s Study (JECS)
Creators: name: Sasaki, Hatoko
name: Pak, Kyongsun
name: Mezawa, Hidetoshi
name: Yamamoto-Hanada, Kiwako
name: Ishitsuka, Kazue
name: Konishi, Mizuho
name: Nishizato, Minaho
name: Sato, Miori
name: Saito-Abe, Mayako
name: Yang, Limin
name: Ohya, Yukihiro
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file2: Supplementary Table 2. Summary of Categorical J-ASQ - Gaussian Method (N = 357)
Process simulation of a thermo-mechanical pulp mill
Creators: name: Bewsher, Glenn David.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
La metodología antes que la tecnología para afrontar la nueva normalidad docente en la universidad
Creators: name: García-Peñalvo, F. J.
Publisher: name: Zenodo
Year: 2020
Subjects: eLearning; Metdología docente; Transformación digital; Educación Superior

description: García-Peñalvo, F. J. (2020). La metodología antes que la tecnología para afrontar la nueva normalidad docente en la universidad . Webinar en el Ciclo de Webminars “La nueva realidad docente de la Universidad de Salamanca: Lecciones aprendidas y reflexiones”. Universidad de Salamanca. Salamanca, España: Grupo GRIAL. doi:10.5281/zenodo.3899965
Polyols, increasing global stability of cytochrome c, destabilize the thermal unfolding intermediate
Creators: name: Naidu, K. Tejaswi
name: Prabhu, N. Prakash
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Studies on the intermediate states of proteins provide essential information on folding pathway and energy landscape of proteins. Osmolytes, known to alter the stability of proteins, might also affect the structure and energy states of folding intermediates. This was examined using cytochrome c (Cyt) as a model protein which forms a spectroscopically detectable intermediate during thermal denaturation transition. Most of the secondary structure and the native heme-ligation were intact in the intermediate state of the protein. Denaturants, urea and guanidinium hydrochloride, and ionic salt destabilizes the intermediate and drive the protein to follow two-state transition. The effect of polyol class of osmolytes, glycol, glycerol, erythritol, xylitol and sorbitol (with OH-groups two to six), on the intermediate was studied using Soret absorbance and far-UV circular dichroism. With the increasing concentration of any of the polyols, the transition-midpoint temperature (Tm) and the enthalpy change (ΔH) for native to intermediate transition were decreased. This indicated that the intermediate was destabilized by the polyols. However, the polyols increased the overall stability of the protein by increasing Tm and ΔH for intermediate to unfolded transition, except for glycol which destabilized the protein. These results show that the polyols could alter the energy state of the intermediate, and the effect of lower and higher polyols might be different on the stability and folding pathway of the protein. Communicated by Ramaswamy H. Sarma
Protein degradation: a novel computational approach to design protein degrader probes for main protease of SARS-CoV-2
Creators: name: Shaheer, Muhammed
name: Singh, Ravi
name: Sobhia, M. Elizabeth
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has afflicted many lives and led to approvals of drugs and vaccines for emergency use. Even though vaccines have emerged, the high mortality of COVID-19 and its insurgent proliferation throughout the masses commands an innovative therapeutic proposition for the treatment. Targeted protein degradation has been applied to various disease domains and we propose that it could be incredibly beneficial to tackle the current pandemic. In this study, we have attempted to furnish insights on the design of suitable PROTACs for the main protease (Mpro) of SARS-CoV-2, a protein that is considered to be an essential target for viral replication. We have employed protein-protein docking to predict the possible complementarity between a cereblon E3 ligase and Mpro of SARS-CoV-2, and estimate possible linker length. Molecular Dynamic simulation and analysis on generated ternary complexes demonstrated stable interactions that suggested that designed PROTAC has a potential to cause degradation. The superior characteristics rendered by PROTACS led us to propose them as possibly the next-generation antiviral drugs for SARS-CoV-2. Communicated by Ramaswamy H. Sarma
Wpływ flokulacji drobnoziarnistej frakcji łupka miedzionośnego na jego flotację w celce Hallimonda
Creators: name: Kruszelnicki, Mateusz
name: Legawiec, Krzysztof J.
name: Skrzyszowska, Maja
Publisher: name: Wydział Geoinżynierii, Górnictwa i Geologii, Politechnika Wrocławska, Wrocław / Faculty of Geoengineering, Mining and Geology, Wrocław University of Science and Technology, Wrocław
Year: 2018

description: Łupek miedzionośny IV, Ratajczak T., Drzymała J. (red.), WGGG PWr, Wrocław, ISBN 978-83-946706-7-2
Design and in silico investigation of novel Maraviroc analogues as dual inhibition of CCR-5/SARS-CoV-2 Mpro
Creators: name: Basha, G. Mahaboob
name: Parulekar, Rishikesh S.
name: Al-Sehemi, Abdullah G.
name: Pannipara, Mehboobali
name: Siddaiah, Vidavalur
name: Kumari, Sunanda
name: Choudhari, Prafulla B.
name: Tamboli, Yasinalli
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: A sudden increase in life-threatening COVID-19 infections around the world inflicts global crisis and emotional trauma. In current study two druggable targets, namely SARS-COV-2 Mpro and CCR-5 were selected due to their significant nature in the viral life cycle and cytokine molecular storm respectively. The systematic drug repurposing strategy has been utilized to recognize inhibitory mechanism through extensive in silico investigation of novel Maraviroc analogues as promising inhibitors against SARS-CoV-2 Mpro and CCR-5. The dual inhibition specificity approach implemented in present study using molecular docking, molecular dynamics (MD), principal component analysis (PCA), free energy landscape (FEL) and MM/PBSA binding energy studies. The proposed Maraviroc analogues obtained from in silico investigation could be easily synthesized and constructive in developing significant drug against COVID-19 pandemic, with essentiality of their in vivo/in vitro evaluation to affirm the conclusions of this study. This will further fortify the concept of single drug targeting dual inhibition mechanism for treatment of COVID-19 infection and complications. Communicated by Ramaswamy H. Sarma
Additional file 1 of Airway and systemic biomarkers of health effects after short-term exposure to indoor ultrafine particles from cooking and candles – A randomized controlled double-blind crossover study among mild asthmatic subjects
Creators: name: Laursen, Karin Rosenkilde
name: Christensen, Nichlas Vous
name: Mulder, Frans AA
name: Schullehner, Jörg
name: Hoffmann, Hans Jürgen
name: Jensen, Annie
name: Møller, Peter
name: Loft, Steffen
name: Olin, Anna-Carin
name: Rasmussen, Berit B.
name: Rosati, Bernadette
name: Strandberg, Bo
name: Glasius, Marianne
name: Bilde, Merete
name: Sigsgaard, Torben
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
classificationCode: 29999
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 110309
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
In silico design of epitope-based peptide vaccine against non-typhoidal Salmonella through immunoinformatic approaches
Creators: name: Ali, Md. Chayan
name: Khatun, Mst. Shanzeda
name: Jahan, Sultana Israt
name: Das, Raju
name: Munni, Yeasmin Akter
name: Rahman, Md Mafizur
name: Dash, Raju
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Non-typhoidal Salmonella (NTS) is one of the leading bacterial causes of many invasive human infections with a high antibiotic resistance profile. With this concern, the current study aimed to design an effective epitope-based peptide vaccine against NTS species as a successive and substitutive protective measure of invasive NTS disease. To design rationally, the current study considered a comprehensive in silico workflow combination of both immunoinformatics and molecular modeling approaches, including molecular docking and molecular dynamics (MD) simulation. We identified the two most promising T cell epitopes KVLYGIFAI and YGIFAITAL, and three B cell epitopes AAPVQVGEAAGS, TGGGDGSNT, and TGGGDGSNTGTTTT, in the outer membrane of NTS. Using these epitopes, a multiepitope vaccine was subsequently constructed along with appropriate adjuvant and linkers, which showed a good binding affinity and stability with toll-like receptor 2 (TLR2) in both molecular docking and MD simulation. Furthermore, in silico immune simulation described a strong immune response with a high number of antibodies, interferon-γ, and activated B and T cells. This study collectively suggests that predicted vaccine constructs could be considered potential vaccine candidates against common NTS species. Communicated by Ramaswamy H. Sarma