cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Molecular characterization, expression pattern and function analysis of the rice OsDUF866 family
Creators: name: Li, Lihua
name: Xie, Chen
name: Ye, Taozhi
name: Xu, Jinghong
name: Chen, Rongjun
name: Gao, Xiaoling
name: Zhu, Jianqing
name: Xu, Zhengjun
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Domain-of-unknown function (DUF) proteins represent a number of gene families with no functional annotation in the Pfam database. So far, the DUF866 family has not been characterized, and no member has been functionally studied. In this study, we uncovered and analysed four OsDUF866 (OsDUF866.1–OsDUF866.4) family members in rice Nipponbare, in which three distinct motifs were identified. The expression of OsDUF866 family in nine tissues was examined by real-time polymerase chain reaction (PCR), and the highest expression of four genes members was found in embryos at 14 days after flowering. We performed real-time PCR to examine the expression of OsDUF866 family under abiotic stress and abscisic acid (ABA) treatment conditions. The expression level of OsDUF866.1 displayed significant decrease under drought and salt conditions, while significant increase under heat conditions. The expression level of OsDUF866.2 displayed significant decrease under drought conditions. The expression level of OsDUF866.3 was significantly elevated under drought and cold, while lowered under heat conditions. The expression level of OsDUF866.4 was increased under cold and heat conditions, while decreased under drought conditions. Interestingly, the expression level of OsDUF866 members was approximately constant under ABA treatment conditions. Overexpression of OsDUF866.1 in Escherichia coli could enhance cell viability and significantly improve the resistance to heat stress conditions. The results may provide new insights into the function of OsDUF866 family in rice.
CoESRA: From virtual desktop to science gateway
Creators: name: Nguyen, Hoang Anh
name: Abramson, David
name: Guru, Siddesware
name: Sun, Yi
Publisher: name: figshare
Year: 2017
Subjects: classificationCode: 460699
subject: Distributed computing and systems software not elsewhere classified
classificationCode: 460605
subject: Distributed systems and algorithms
classificationCode: 460199
subject: Applied computing not elsewhere classified
classificationCode: 461299
subject: Software engineering not elsewhere classified

description: The Collaborative Environment for Ecosystem Science Research and Analysis (CoESRA) is a Web-based virtual desktop environment that integrates existing eResearch infrastructure in Australia for synthesis and analysis of scientific data for the ecological science community. Data synthesis and analysis is performed through scientific workflows. Even though this is powerful, it has a large learning curve for novice users. We have implemented a Web layer on top of an existing virtual desktop layer to hide this complexity from users. This new layer allows users to execute scientific workflows without requiring a desktop, and thus reduces the learning curve. The virtual desktop is still accessible for more advanced users.
Revisiting the size selective performance of EPA's high-volume total suspended particulate matter (Hi-Vol TSP) sampler
Creators: name: Krug, Jonathan D.
name: Dart, Andrew
name: Witherspoon, Carlton L.
name: Gilberry, Jerome
name: Malloy, Quentin
name: Kaushik, Surender
name: Vanderpool, Robert W.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Under the National Ambient Air Quality Standard (NAAQS) for airborne lead, measurements are conducted by means of a high-volume total suspended particulate matter (Hi-Vol TSP) sampler. In the decade between 1973 and 1983, there were 12 publications that explored the sampling characteristics and effectiveness of the Hi-Vol TSP, yet there persists uncertainty regarding its performance. This article presents an overview of the existing literature on the performance of the Hi-Vol TSP, and identifies the reported sampler effectiveness with respect to four factors: particle size (reported effectiveness of 7%–100%), wind speed (−36% to 100%), sampler orientation (7%–100%), and operational state (107%–140%). Effectiveness of the Hi-Vol TSP was evaluated with a solid, polydisperse aerosol in a controlled wind tunnel setting. Isokinetic samplers were deployed alongside the Hi-Vol TSP to investigate three wind speeds (2, 8, and 24 km h−1), three sampler orientations (0°, 45°, 90°), and two operational states (on, off) for aerosols with aerodynamic diameters from 5 to 35 µm. Results indicate that particle diameter was the largest determining factor of effectiveness followed by wind speed. Orientation of the sampler did not have a significant effect at 2 and 8 km h−1 but did at 24 km h−1. In a passive state, the Hi-Vol TSP was collected between 1% and 7% of available aerosol depending on particle size and wind speed. Results of this research do not invalidate results of previous studies but rather contribute to our overall understanding of the Hi-Vol TSP's size-selective performance. While results generally agreed with previous studies, the Hi-Vol TSP was found to exhibit less dependence on these four factors than previously reported. © 2017 American Association for Aerosol Research
A Regioselective and Convenient One-Pot Multi-Component Synthesis of 9-Amino-3,5-Diaryl-4,9-Dihydro-5H-[1,2,4]Triazolo[5,1-C] [1,2,4]Triazepine-8-thiol
Creators: name: Moustafa, Amr Hassan
name: Amer, Amer Anwar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: An efficient and environment-friendly procedure for the synthesis of a new series of nitrogen bridge-head [1,2,4]triazolo[5,1-C][1,2,4]triazepine derivatives via one-pot three component reaction of polyfunctional triazole with aromatic aldehydes and acetophenone derivatives using alcoholic sodium hydroxide solution. The same new products were prepared in classical route via reaction of triazole with the corresponding chalcones under the same conditions.
CoESRA: From virtual desktop to science gateway
Creators: name: Nguyen, Hoang Anh
name: Abramson, David
name: Guru, Siddesware
name: Sun, Yi
Publisher: name: figshare
Year: 2016
Subjects: classificationCode: 460699
subject: Distributed computing and systems software not elsewhere classified
classificationCode: 460605
subject: Distributed systems and algorithms
classificationCode: 460199
subject: Applied computing not elsewhere classified
classificationCode: 461299
subject: Software engineering not elsewhere classified

description: The Collaborative Environment for Ecosystem Science Research and Analysis (CoESRA) is a Web-based virtual desktop environment that integrates existing eResearch infrastructure in Australia for synthesis and analysis of scientific data for the ecological science community. Data synthesis and analysis is performed through scientific workflows. Even though this is powerful, it has a large learning curve for novice users. We have implemented a Web layer on top of an existing virtual desktop layer to hide this complexity from users. This new layer allows users to execute scientific workflows without requiring a desktop, and thus reduces the learning curve. The virtual desktop is still accessible for more advanced users.
Technik- und Naturwissenschaft als (auto-) biographischer Stoff? – Konzepte von Identität, Karriere und Rechtschaffenheit im Wissenschaftsbetrieb
Creators: name: Buck, Henning
Publisher: name: Universität Osnabrück
Year: 1994
Subjects: subject: Autiobiografie
subject: 800 - Literatur, Rhetorik, Literaturwissenschaft
subject: 500 - Naturwissenschaften
subject: 620 - Ingenieurwissenschaften und Maschinenbau
subject: 610 - Medizin, Gesundheit
subject: 02.00 - Wissenschaft und Kultur allgemein: Allgemeines

description: Eine Untersuchung zu autobiografischen Selbstdarstellungen von deutschsprachigen Technik- und Naturwissenschaftlern im 20. Jahrhundert, mit einer Auswahlbibliografie
Revisiting the Size Selective Performance of EPA's High-Volume Total Suspended Particulate Matter (Hi-Vol TSP) Sampler
Creators: name: Krug, Jonathan D.
name: Dart, Andrew
name: Witherspoon, Carlton L.
name: Gilberry, Jerome
name: Malloy, Quentin
name: Kaushik, Surender
name: Vanderpool, Robert W.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: Under the National Ambient Air Quality Standard (NAAQS) for airborne lead measurements are conducted by means of a High-Volume Total Suspended Particulate Matter (Hi-Vol TSP) sampler. In the decade between 1973 and 1983, there were 12 publications that explored the sampling characteristics and effectiveness of the Hi-Vol TSP, yet there persists uncertainty regarding its performance. This paper presents an overview of the existing literature on the performance of the Hi-Vol TSP, and identifies the reported sampler effectiveness with respect to four factors: particle size (reported effectiveness of 7–100%), wind speed (−36–100%), sampler orientation (7–100%), and operational state (107–140%). Effectiveness of the Hi-Vol TSP was evaluated with a solid, polydisperse aerosol in a controlled wind tunnel setting. Isokinetic samplers were deployed alongside the Hi-Vol TSP to investigate three wind speeds (2, 8, and 24 km/hr), three sampler orientations (0°, 45°, 90°), and two operational states (on, off) for aerosols with aerodynamic diameters from 5 to 35 µm. Results indicate that particle diameter was the largest determining factor of effectiveness followed by wind speed. Orientation of the sampler did not have a significant effect at 2 and 8 km/hr but did at 24 km/hr. In a passive state, the Hi-Vol TSP collected between 1 and 7% of available aerosol depending on particle size and wind speed. Results of this research do not invalidate results of previous studies but rather contribute to our overall understanding of the Hi-Vol TSP's size-selective performance. While results generally agreed with previous studies, the Hi-Vol TSP was found to exhibit less dependence on these four factors than previously reported.
Silver(I), nickel(II) N-heterocyclic carbene complexes based on bidentate bis-imidazolium salt with a quinoxaline linker: syntheses, structures, and characterization
Creators: name: Xia, Changkun
name: Yang, Kai
name: Sun, Wen
name: Lu, Xiaojing
name: Xie, Jimin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Quinoxaline-bridged bidentate bis-imidazolium dicarbene ligand 1,1′-(quinoxaline-2,3-diyl)bis(3-methyl-1H-imidazol-3-ium) hexafluorophosphate salt H2L·2PF6 (3) was prepared by a two-step reaction based on 2,3-bis(imidazol-1-yl)quinoxaline (1). First, the 2,3-bis(imidazol-1-yl)quinoxaline reacted with CH3I resulting in the 1,1′-(quinoxaline-2,3-diyl)bis(3-methyl-1H-imidazol-3-ium) iodide salt H2L·2I (2), then through anion exchange reactions with NH4PF6 in water produced the desired bis-imidazolium bidentate ligand H2L·2PF6 (3). Reaction of the bidentate bis-imidazolium ligands H2L·2PF6 (3) with Ag2O in acetonitrile gave the macrocyclic binuclear silver(I) carbene complex [Ag2(L)2]·2PF6·CH3CN (4). Nickel carbene complex [Ni(L)PPh3Cl]·PF6·2DMSO (5) was obtained via transmetalation of 4 with Ni(PPh3)2Cl2 in DMSO. The bidentate carbene ligand is a chelating ligand in 5, while bridging in 4. The imidazolium ligand H2L·2PF6 (3) and transition metal carbene complexes 4 and 5 have been fully characterized by elemental analysis, NMR, ESI-MS spectroscopy, and X-ray diffraction analyses. Furthermore, the UV and luminescent properties of 3–5 were also studied.
An analysis of the Human Resource practices in the mining industry in Zimbabwe’s Midlands Province: A relook at the Resource Based View of managing Human Resources.
Creators: name: Nyamubarwa, Willard
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 350599
subject: Human resources and industrial relations not elsewhere classified
classificationCode: 350503
subject: Human resources management
classificationCode: 350504
subject: Industrial and employee relations
classificationCode: 350505
subject: Occupational and workplace health and safety

description: The mining industry across the globe has always made use of large stocks of labourto achieveorganizational objectives. It is against this background that the study was conducted to determine the HR practices currently being implemented in the mining sector in Zimbabwe. The Results Based View approach to the strategic leadership of organisations was adopted to act as a benchmark against which the current HR practices can be compared with. The research data was gathered through a non-random, convenient sample of HR managers from 8 mining entities in the Midlands Province of Zimbabwe. Convenience sampling was necessitated by the limited finances and time at the disposal of the researcher. However, the relatively large size of the sample would ensure a high degree of generalisability of findings for the mining industry in the Midlands Province in Zimbabwe. The findings of the study revealed that in the mining industry in Zimbabwe, employees are treated as valuable, rare and inimitable resource which they deploy in various ways to achieve organisational objectives. As such the mining companies have come up with innovative methods of managing their human resources which includes providing job security, competitive rewards, and social welfare services amongst other methods. These findings confirm that HR departments in the mining industry in Zimbabwe’s Midlands Province are practising the RBV approach to the management of human resources in their organisations and by so doing manage to resource their mining entities efficiently and effectively.
A New Cascade Reaction of Azides with Malononitrile Dimer to Polyfunctional [1,2,3]triazolo[4,5-b]pyridine
Creators: name: Nazariy T. Pokhodylo
name: Shyyka, Olga Ya.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: A new cascade reaction of azides with malononitrile dimer yielding polyfunctional [1,2,3]triazolo[4,5-b]pyridine was found. It was established that during the reaction of arylazides with malononitrile dimer, under base catalysis, the formed intermediate triazole underwent spontaneous cyclization leading to the pyridine ring annulation. The obtained products have provided a new entry to [1,2,3]triazolo[4,5-b]pyridine.
Silver(I), nickel(II) N-heterocyclic carbene complexes based on bidentate bis-imidazolium salt with a quinoxaline linker: Syntheses, structures, and characterization
Creators: name: Xia, Changkun
name: Yang, Kai
name: Sun, Wen
name: Lu, Xiaojing
name: Xie, Jimin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Quinoxaline bridged bidentate bis-imidazolium dicarbene ligand 1,1’-(quinoxaline-2,3-diyl)bis(3-methyl-1H-imidazol-3-ium) hexafluorophosphate salt H2L·2PF6 (3) was prepared by a two-step-reaction based on 2,3-bis(imidazol-1-yl)quinoxaline (1). First, the 2,3-bis(imidazol-1-yl)quinoxaline reacted with CH3I resulting in the 1,1’-(quinoxaline-2,3-diyl)bis(3-methyl-1H-imidazol-3-ium) iodide salt H2L·2I (2), then though anion exchange reactions with NH4PF6 in water produced the desired bis-imidazolium bidentate ligand H2L·2PF6 (3). Reaction of the bidentate bis-imidazolium ligands H2L·2PF6 (3) with Ag2O in acetonitrile gave the macrocyclic binuclear silver(I) carbene complex [Ag2(L)2]·2PF6·CH3CN (4). Nickel carbene complex [Ni(L)PPh3Cl]·PF6·2DMSO (5) was obtained via transmetalation of 4 with Ni(PPh3)2Cl2 in DMSO. The bidentate carbene ligand is a chelating ligand in 5, while bridging in 4. The imidazolium ligand H2L·2PF6 (3) and transition metal carbene complexes 4 and 5 have been fully characterized by elemental analysis, NMR, ESI-MS spectroscopy, and X-ray diffraction analyses. Furthermore, the UV and luminescent properties of 3-5 were also studied.
Impact of intraoperative MRI-guided resection on resection and survival in patient with gliomas: a meta-analysis
Creators: name: Li, Ping
name: Qian, Ruobing
name: Niu, Chaoshi
name: Fu, Xianming
Publisher: name: Taylor & Francis
Year: 2016
Subjects: Medicine
Cell Biology
Biotechnology
Cancer
Science Policy

description: Objective: This study addressed the benefit of intraoperative magnetic resonance imaging (iMRI) compared with conventional neuronavigation-guided resection in patients with gliomas. Research design and methods: The Medline, PubMed, Cochrane, and Google Scholar databases were searched up to 26 September 2015. Randomized controlled trials (RCTs), two-arm prospective studies, and retrospective studies in patients with glioblastoma/glioma who had received surgical treatment were included. Main outcome measures: The primary outcome measures were the extent of tumor resection and tumor size reduction for using iMRI-guided or conventional neuronavigation-guided neurosurgery. Secondary outcomes included impact of surgery on 6 month progression-free survival (PFS), 12 month overall survival (OS) rates and surgical duration. Results: We found that iMRI was associated with greater rate of gross total resection (rGTR) compared with conventional neuronavigation procedures (3.16, 95% confidence interval [CI] 2.07–4.83, P < .001). We found no difference between the two neuronavigation approaches in extent of resection (EOR), tumor size reduction, or time required for surgery (P values ≥.065). Intraoperative MRI was associated with a higher rate of progression-free survival (PFS) compared with conventional neuronavigation (odds ratio, 1.84; 95% CI 1.15–2.95; P = .012), but the rate of overall survival (OS) between groups was similar (P = .799). Limitations of the study included the fact that data from non-RCTs was used, the small study population, and heterogeneity of outcomes across studies. Conclusions: Our findings indicate that iMRI more frequently resulted in more complete resections leading to improved PFS in patients with malignant gliomas.
Efficient synthesis of thioglycosylated kojic acid by s-glycosyl isothiouronium salts
Creators: name: Wu, Zhimeng
name: Cao, Aijie
name: Ding, Wenzhang
name: Zhu, Tao
name: Shen, Peng
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: In this study, 7-S-glycosides of kojic acid were designed and synthesized as mimics of its 7-O-glycosides to improve its water solubility and metabolic stability. To achieve this synthesis, a one-pot approach involving S-glycosyl isothiouronium salts generated in situ as key intermediates was developed by using 7-chloro-kojic acid as the alkylation reagent. A series of water soluble 7-S-glycosides of kojic acid, incorporating monosaccharides and disaccharides, were prepared using this protocol. Thus, this work offers a mild, convenient, and efficient approach for the synthesis of 7-S-glycosides of kojic acid in medium to good yields.
Supplementary Material
Creators: name: Ortega Sánchez, Francisco Gabriel
Publisher: name: figshare
Year: 2022
Subjects: subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Supplementary Material. ANTIFIBROTIC EFFECTS OF EXTRACELLULAR VESICLES FROM UMBILICAL CORD-MESENCHYMAL STEM CELLS ON LUNG PRO-FIBROTIC CELLS
Syntheses, structures and catalytic activity for Friedel-Crafts reactions of substituted indenyl rhenium carbonyl complexes
Creators: name: Ma, Zhihong
name: Zhang, Xinli
name: Wang, Hong
name: Han, Zhangang
name: Zheng, Xuezhong
name: Lin, Jin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: The complexes [(η5-C9H6R)Re(CO)3] [R = nBu (8), tBu (9), CH(CH2)4 (10), Ph (11), Bz (12), 4-methoxyphenyl (13), 4-chlorophenyl (14)] were synthesized by refluxing substituted indenyl ligands [C9H7R] [R = nBu (1), tBu (2), CH(CH2)4 (3), Ph (4), Bz (5), 4-methoxyphenyl (6), 4-chlorophenyl (7)], and Re2(CO)10 in decalin. The molecular structures of 9, 10, 12, and 13 were determined by X-ray diffraction analysis. These four crystals have similar molecular structures of the mononuclear carbonyl complex. In each of these molecules, Re is η5-coordinated to the five-membered ring of the indenyl group. Complexes 8–14 have catalytic activity for Friedel-Crafts reactions of aromatic compounds with a variety of alkylation and acylation reagents. Compared with traditional catalysts, these mononuclear metal carbonyl complexes have obvious advantages such as high activities, mild reaction conditions, high selectivity, and environmentally friendly chemistry.
Two new coumarins from the bark of Streblus indicus (Bur.) Corner
Creators: name: He, Ruijie
name: Deng, Shengping
name: Nie, Hui
name: Huang, Yan
name: Liu, Buming
name: Yang, Ruiyun
name: Huang, Shuai
name: Zhou, Dexiong
name: Chen, Huangcan
name: Li, Jun
name: Zhang, Yanjun
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Two new coumarins 7-O-(6-O-(5-O-3,4,5-tri-methoxycinnamate-β-d-apiofuranosyl-β-d-glucopyranosyl)-6-methoxy coumarin (1) and 7-O-(6-O-(4-(2-hydroxy-1-hydroxymethyl-ethoxy)-3-methoxy-cinnamyl)-β-d-glucopyranosyl)-6-methoxy coumarin (2), along with 10 known metabolites, were isolated from the bark of Streblus indicus, their structures were identified by comparison of experimental and published spectroscopic data. (S)-marmesinin (6) and scoparone (7) exhibited moderate antimicrobial activity in vitro against Staphylococcus aureus strain with the MIC values of 62.5 and 125.0 μg/mL, respectively. Betulinic acid showed inhibitory activity in vitro against MCF-7 cell with IC50 value of 9.5 ± 0.1 μM.
Evaluation of the sedative and hypnotic effects of astragalin isolated from Eucommia ulmoides leaves in mice
Creators: name: Li, Xin
name: Tang, Zichen
name: Fei, Dongqing
name: Liu, Yunhong
name: Zhang, Min
name: Liu, Shaoyang
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The purpose of this study was to evaluate the effects of astragalin on the central nervous system. Astragalin is a monomeric compound found in the leaves of Eucommia ulmoides using a system solvent method. In the experiments, astragalin showed significant effects on mice, including reduced spontaneous activity, increased sleep ratio, shortened sleep latency and lengthened sleep time with a subthreshold or superthreshold dose of pentobarbital sodium. In addition, astragalin effectively reduced the convulsion rate and prolonged convulsion latency. These findings confirmed that astragalin had excellent sedative and hypnotic effects and has potential to be commercialised as a novel nutraceutical agent to promote calming and improve central nervous system-associated pathologies.
α-Glucosidase inhibitors and phytotoxins from Streptomyces xanthophaeus
Creators: name: Wei, Jing
name: Zhang, Xiu-Yun
name: Deng, Shan
name: Cao, Lin
name: Xue, Quan-Hong
name: Gao, Jin-Ming
Publisher: name: Taylor & Francis
Year: 2016
Subjects: Biochemistry
Space Science
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer

description: Twenty-four metabolites 1–24 were isolated from the fermentation broth of Streptomyces xanthophaeus. Their structures were elucidated on the basis of spectroscopic analysis and by comparison of their NMR data with literature data reported. Daidzein (1), genistein (2) and gliricidin (3) inhibited α-glucosidase in vitro with IC50 values of 174.2, 36.1 and 47.4 μM, respectively, more potent than the positive control, acarbose. Docking study revealed that the amino acid residue Thr 215 is the essential binding site for active ligands 2. In addition, the phytotoxic effects of all compounds were assayed on radish seedlings, five of which, 3, 8, 13, 15 and 18, inhibited the growth of radish (Raphanus sativus) seedlings with inhibitory rates of >60% at a concentration of 100 ppm, which was comparable or superior to the positive control glyphosate. This is the first report of the phytotoxicity of the compounds.
Theoretical investigation of different reactivities of Fe(IV)O and Ru(IV)O complexes with the same ligand topology
Creators: name: Tang, Zhe
name: Wang, Yi
name: Zhang, Peng
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Neuroscience
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The structures and mechanisms for hydrogen abstraction from isopropylbenzene for four high-valence complexes, cis-β-[FeIV(O)(BQCN)]2+ (Fe-2b and Fe-2b-2) and cis-β-[RuIV(O)(BQCN)]2+ (Ru-2b and Ru-2b-2) (BQCN = N,N′-dimethyl-N,N′-bis(8-quinolyl)-cyclohexanediamine), were investigated using density functional theory. Of the two iron complexes, Fe-2b-2 has more exposed FeO units than Fe-2b, with iron being further out of the equatorial plane because of the steric interaction of the same ligand topologies with the iron-oxo group trans to a quinolyl or amine nitrogen. The contribution of BQCN to Fe-2b is higher than the contribution to Fe-2b-2 as shown by the density-of-states spectra. The iron isomers can abstract hydrogen from isopropylbenzene via two-state reactivity patterns, whereas the ruthenium isomers react with isopropylbenzene via a single-state mechanism. In the gas phase, the relative reactivity exhibits the trend Fe-2b > Fe-2b-2, whereas with the addition of the ZPE correction and the SMD model, the relative reactivity follows Fe-2b-2 > Fe-2b. For the ruthenium complexes, the relative reactivity follows the trend Ru-2b-2 > Ru-2b in both the gas phase and solvent. Thus, the same ligand topologies with the metal-oxo group trans to a different nitrogen affect the reactivities of the iron and ruthenium complexes.
High-throughput thermal stability assessment of DNA hairpins based on high resolution melting
Creators: name: Wang, Jing
name: Dong, Ping
name: Wu, Wei
name: Pan, Xiaoming
name: Liang, Xingguo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: On the basis of high-resolution melting, a high-throughput approach to measure melting temperatures (Tms) of short DNA hairpins was developed. With this method, Tms of thousands of triloop, tetraloop, and pentaloop hairpins involving various loop sequences and various closing base pairs (cbp) were obtained in hours. The stability of triloop hairpins decreased with the change of cbp (5′–3′) in the order of c-g > g-c > t-a ≥ a-t, showing that the cbp of 5′-Pyr-Pur-3′ (Pyr = pyrimidine, Pur = purine) contributed more stability than 5′-Pur-Pyr-3′. For tetraloop hairpins, GNNA, GNAB, and CNNG (N = A, G, C, or T; B = G, C, or T) were found to be highly stable irrespective of the cbp type. TNNA was also stable in both g-c and a-t families, while CGNA only in the c-g family. Pentaloop hairpins of cTGNAGg, cGNYNAg (Y = T or C) and cCGNNAg were exceptionally stable motifs. In most cases, pyrimidine-rich loops were more favorable to stabilize the whole structure than purine-rich ones. The present approach showed a good performance in assessing the thermal stability of large amounts of DNA hairpins comprehensively. These data are useful to understand the sequence dependence of the stability of DNA secondary structures and promising to improve the structure simulation by consummating basic databases.
Investigation on evaluation criteria of backwashing effects for a pilot-scale BAF treating petrochemical wastewater
Creators: name: Fu, Liya
name: Wu, Changyong
name: Zhou, Yuexi
name: Zuo, Jiane
name: Ding, Yan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Parameters for evaluation criteria of air–water backwashing effects of a pilot-scale biological aerated filter (BAF) treating petrochemical wastewater were investigated. The parameters included the suspended solids (SS) and specific oxygen uptake rate (SOUR) of the backwashing effluent, recovery of the BAF after backwashing, and the removal of the biomass/bioactivity attached on the filter media after backwashing. Results showed that the weight of the total sludge produced in the backwashing effluent increased with the increase in water-backwashing intensity, while the total SOUR of backwashing effluent rose notably with the increase of air-backwashing intensity. The optimal backwashing intensity of 14 L/(m2·s) for air and 4 L/(m2·s) for water were obtained. When the BAF was backwashed on this condition, the BAF recovered with high average removal of chemical oxygen demand (COD) and ammonia nitrogen of 14.3% and 50.3%, respectively. High amount of biomass removal at 15.8% and low level of bioactivity removal at 8.8% attached on the filter media were also found. Concentrations of the benzene, toluene, ethylbenzene and (o-, m-, p-) xylenes (BTEX) and phenol in the backwashed sludge were analyzed, showing that the backwashing was essential to remove some aromatic compounds adsorbed in the microorganisms.
Cost-effectiveness of sequenced treatment of rheumatoid arthritis with targeted immune modulators
Creators: name: Jansen, Jeroen P.
name: Incerti, Devin
name: Mutebi, Alex
name: Peneva, Desi
name: MacEwan, Joanna P.
name: Stolshek, Bradley
name: Primal Kaur
name: Gharaibeh, Mahdi
name: Strand, Vibeke
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Aims: To determine the cost-effectiveness of treatment sequences of biologic disease-modifying anti-rheumatic drugs or Janus kinase/STAT pathway inhibitors (collectively referred to as bDMARDs) vs conventional DMARDs (cDMARDs) from the US societal perspective for treatment of patients with moderately to severely active rheumatoid arthritis (RA) with inadequate responses to cDMARDs. Materials and methods: An individual patient simulation model was developed that assesses the impact of treatments on disease based on clinical trial data and real-world evidence. Treatment strategies included sequences starting with etanercept, adalimumab, certolizumab, or abatacept. Each of these treatment strategies was compared with cDMARDs. Incremental cost, incremental quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs) were calculated for each treatment sequence relative to cDMARDs. The cost-effectiveness of each strategy was determined using a US willingness-to-pay (WTP) threshold of $150,000/QALY. Results: For the base-case scenario, bDMARD treatment sequences were associated with greater treatment benefit (i.e. more QALYs), lower lost productivity costs, and greater treatment-related costs than cDMARDs. The expected ICERs for bDMARD sequences ranged from ∼$126,000 to $140,000 per QALY gained, which is below the US-specific WTP. Alternative scenarios examining the effects of homogeneous patients, dose increases, increased costs of hospitalization for severely physically impaired patients, and a lower baseline Health Assessment Questionnaire (HAQ) Disability Index score resulted in similar ICERs. Conclusions: bDMARD treatment sequences are cost-effective from a US societal perspective.
Synthesis, Characterization and Theoretical Calculations of a New Fluorescent Probe for Detection Cu2+
Creators: name: Zhao, Junxia
name: Gao, Qi
name: Zhang, Feifei
name: Sun, Wei
name: Bai, Yinjuan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: Biochemistry
Neuroscience
Chemical Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: A novel rhodamine-based probe (RP1) was synthesized and characterized as a colorimetric chemosensor with high selectivity and sensitivity in biological systems toward Cu2+ over other cations tested. RP1 showed low detection limit for copper. The binding between RP1 and Cu2+ was confirmed to be stoichiometric. The recognition process was reversible. We also performed the density functional theory (DFT) calculation to have more understanding of structure, molecular and electronic.
Developing an Effective Market for Open Access Article Processing Charges
Creators: name: Bo-Christer Björk
name: Solomon, David
Publisher: name: Wellcome Trust
Year: 2017
Subjects: Science Policy

description: A report commissioned by Jisc, Research Libraries UK, Research Councils UK, the Wellcome Trust, the Austrian Science Fund (FWF), the Luxembourg National Research Fund and the Max Planck Institute for Gravitational Physics.
Originally published in March 2014.
Discrimination of Alismatis Rhizoma based on chromatographic fingerprint, multiple components quantification, and pattern recognition analysis
Creators: name: Yu, Jingyi
name: Ma, Xueyang
name: Wang, Jun
name: Liang, Hong
name: Zhang, Qingying
name: Chen, Shizhong
name: Tu, Pengfei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Hematology

description: A simple, sensible, and reliable HPLC–DAD method was first developed for fingerprint analysis of Alismatis Rhizoma, and then applied to analyze 85 samples from three main cultivated areas. In all, 40 common fingerprint peaks were designated, and six of which were definitely identified. Then, the combinatory analysis using similarity evaluation, principal component analysis, and orthogonal partial least square discriminant analysis revealed clear chemical consistency between samples from Fujian and Jiangxi provinces and substantial differences between those from Fujian/Jiangxi and Sichuan provinces. Furthermore, six components were dug out as potential chemical markers for distinguishing Alismatis Rhizoma from different areas, among which five were qualified for quantitative analysis. In conclusion, the combination of chemical fingerprint, multiple components quantification, and pattern recognition analysis was rather powerful and useful in discriminating Alismatis Rhizoma from different regions, which was a benefit for quality control.
Discrimination of Alismatis Rhizoma Based on Chromatographic Fingerprint, Multiple Components Quantification and Pattern Recognition Analysis
Creators: name: Yu, Jingyi
name: Ma, Xueyang
name: Wang, Jun
name: Liang, Hong
name: Zhang, Qingying
name: Chen, Shizhong
name: Tu, Pengfei
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: A simple, sensible and reliable HPLC-DAD method was firstly developed for fingerprint analysis of Alismatis Rhizoma, and then applied to analyze 85 samples from three main cultivated areas. Forty common fingerprint peaks were designated, and six of which were definitely identified. Then, the combinatory analysis using similarity evaluation, PCA and OPLS-DA revealed clear chemical consistency between samples from Fujian and Jiangxi provinces and substantial differences between those from Fujian/Jiangxi and Sichuan provinces. Furthermore, six components were dug out as potential chemical markers for distinguishing Alismatis Rhizoma from different areas, among which five were qualified for quantitative analysis. In conclusion, the combination of chemical fingerprint, multiple components quantification and pattern recognition analysis was rather powerful and useful in discriminating Alismatis Rhizoma from different regions, which was a benefit for quality control.
Supplementary material in support of Bacteriophage Co-option from Co-option of bacteriophage lysozyme genes by bivalve genomes
Creators: name: Ren, Qian
name: Wang, Chunyang
name: Jin, Min
name: Lan, Jiangfeng
name: Ye, Ting
name: Hui, Kaimin
name: Tan, Jingmin
name: Wang, Zheng
name: Wyckoff, Gerald J.
name: Wang, Wen
name: Han, Guan-Zhu
Publisher: name: The Royal Society
Year: 2016

description: Broader phylogenetic and molecular data necessary to replicate results.
A new androstanoid metabolite from a soil fungus Curvularia borreriae strain HS-FG-237
Creators: name: Liu, Li-Fei
name: Zhang, Hui
name: Qi, Huan
name: Wang, Xiao-Ming
name: Wang, Ji-Dong
name: Tan, Gui-Shan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cells by CCK-8 assay and weak anti-inflammatory activity in an ANA-1 murine macrophages model.
The yields, agronomic, and nitrogen use efficiency traits of wheat cultivars in north China under N-sufficient and -deficient conditions
Creators: name: Gao, Si
name: Zhang, Feifei
name: Zhi, Yiming
name: Chen, Fang
name: Xiao, Kai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: In this study, the yields, yield components, agronomic, and nitrogen use efficiency (NUE) traits of the eighty-four winter wheat cultivars were investigated under nitrogen (N)-sufficient and -deficient conditions. Dramatic variations were observed in the yield and agronomic traits among the cultivars. Based on absolute yields under the N treatments, the cultivars were categorized into N efficiency groups of high, close high, medium, and low, in which the high efficiency group cultivars generally exhibited improved agronomic traits under these contrasting N-supply conditions. Additionally, the wheat cultivars were classified into various N response groups, including toleration, relative toleration, sensitive, and most sensitive based on the ratios of yield under N deficiency to that under N sufficiency. Regression correlation analyses revealed that straw biomass, total biomass, grain N amount, and straw N amount were significantly correlated with yield, suggesting that these traits can be acted as indices in evaluating yield potentials in wheat.
Additional file 1 of The power of women’s and men’s Social Networks to catalyse normative and behavioural change: evaluation of an intervention addressing Unmet need for Family Planning in Benin
Creators: name: Kim, Theresa Y.
name: Igras, Susan
name: Barker, Kathryn M.
name: Diakité, Mariam
name: Lundgren, Rebecka I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1.
Additional file 1 of Describing workplace interventions aimed to improve health of staff in hospital settings – a systematic review
Creators: name: Worley, Verity
name: Fraser, Penny
name: Allender, Steven
name: Bolton, Kristy A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1.
Additional file 2 of The power of women’s and men’s Social Networks to catalyse normative and behavioural change: evaluation of an intervention addressing Unmet need for Family Planning in Benin
Creators: name: Kim, Theresa Y.
name: Igras, Susan
name: Barker, Kathryn M.
name: Diakité, Mariam
name: Lundgren, Rebecka I.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 2.
The Yields, Agronomic and Nitrogen Use Efficiency Traits of the Wheat Cultivars in North China under N-Sufficient and -Deficient Conditions
Creators: name: Gao, Si
name: Zhang, Feifei
name: Zhi, Yiming
name: Chen, Fang
name: Xiao, Kai
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: In this study, the yields, yield components, agronomic and nitrogen use efficiency (NUE) traits of the eighty four winter wheat cultivars were investigated under nitrogen (N)-sufficient and -deficient conditions. Dramatic variations were observed in yield and the agronomic traits among the cultivars. Based on absolute yields under the N treatments, the cultivars were categorized into N efficiency groups of high, close high, medium, and low, in which the high efficiency group cultivars generally exhibited improved agronomic traits under these contrasting N-supply conditions. Additionally, the wheat cultivars were classified into various N response groups, including toleration, relative toleration, sensitive, and most sensitive based on the ratios of yield under N deficiency to that under N sufficiency. Regression correlation analyses revealed that straw biomass, total biomass, grain N amount, and straw N amount were significantly correlated with yield, suggesting that these traits can be acted as indices in evaluating yield potentials in wheat.
A new phenol glycoside from Physalis angulata
Creators: name: Sun, Cheng-Peng
name: Nie, Xiu-Fang
name: Kang, Ning
name: Zhao, Feng
name: Chen, Li-Xia
name: Qiu, Feng
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Virology

description: A new phenol glycoside, physanguloside A (1), was isolated from Physalis angulata together with four known compounds. We report herein, for the first time, the presence of compounds 2–5 in the genus Physalis. The structures of all the compounds were established by NMR, IR, UV and HRESIMS spectroscopic analyses, and comparison with the literature data. All isolated compounds were assayed for inhibitory activity on nitric oxide production by LPS-induced in RAW 264.7 macrophages.