cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bridging the gap between field experiments and machine learning : the EC H2020 B-GOOD project as a case study towards automated predictive health monitoring of honey bee colonies
Creators: name: Dooremalen, Coby
name: Paxton, Robert J.
name: Tehel, Anja
name: Streicher, Tabea
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 595

description: Honey bee colonies have great societal and economic importance. The main challenge that beekeepers face is keeping bee colonies healthy under ever-changing environmental conditions. In the past two decades, beekeepers that manage colonies of Western honey bees (Apis mellifera) have become increasingly concerned by the presence of parasites and pathogens affecting the bees, the reduction in pollen and nectar availability, and the colonies’ exposure to pesticides, among others. Hence, beekeepers need to know the health condition of their colonies and how to keep them alive and thriving, which creates a need for a new holistic data collection method to harmonize the flow of information from various sources that can be linked at the colony level for different health determinants, such as bee colony, environmental, socioeconomic, and genetic statuses. For this purpose, we have developed and implemented the B-GOOD (Giving Beekeeping Guidance by computational-assisted Decision Making) project as a case study to categorize the colony’s health condition and find a Health Status Index (HSI). Using a 3-tier setup guided by work plans and standardized protocols, we have collected data from inside the colonies (amount of brood, disease load, honey harvest, etc.) and from their environment (floral resource availability). Most of the project’s data was automatically collected by the BEEP Base Sensor System. This continuous stream of data served as the basis to determine and validate an algorithm to calculate the HSI using machine learning. In this article, we share our insights on this holistic methodology and also highlight the importance of using a standardized data language to increase the compatibility between different current and future studies. We argue that the combined management of big data will be an essential building block in the development of targeted guidance for beekeepers and for the future of sustainable beekeeping.
Comparative structure-based virtual screening utilizing optimized AlphaFold Model identifies selective HDAC11 inhibitor
Creators: name: Baselious, Fady
name: Hilscher, Sebastian
name: Robaa, Dina
name: Barinka, Cyril
name: Schutkowski, Mike
name: Sippl, Wolfgang
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: HDAC11 is a class IV histone deacylase with no crystal structure reported so far. The catalytic domain of HDAC11 shares low sequence identity with other HDAC isoforms, which makes conventional homology modeling less reliable. AlphaFold is a machine learning approach that can predict the 3D structure of proteins with high accuracy even in absence of similar structures. However, the fact that AlphaFold models are predicted in the absence of small molecules and ions/cofactors complicates their utilization for drug design. Previously, we optimized an HDAC11 AlphaFold model by adding the catalytic zinc ion and minimization in the presence of reported HDAC11 inhibitors. In the current study, we implement a comparative structure-based virtual screening approach utilizing the previously optimized HDAC11 AlphaFold model to identify novel and selective HDAC11 inhibitors. The stepwise virtual screening approach was successful in identifying a hit that was subsequently tested using an in vitro enzymatic assay. The hit compound showed an IC50 value of 3.5 µM for HDAC11 and could selectively inhibit HDAC11 over other HDAC subtypes at 10 µM concentration. In addition, we carried out molecular dynamics simulations to further confirm the binding hypothesis obtained by the docking study. These results reinforce the previously presented AlphaFold optimization approach and confirm the applicability of AlphaFold models in the search for novel inhibitors for drug discovery.
Knowledge management stakes: a marathon, sprint or decathlon
Creators: name: Sussman, Jeff
name: Hall, Bill
name: Burstein, Frada
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: Organizations competing in dynamic environments must be able to effectively marshal their resources to survive and thrive. The most important resource most organizations have is their specialist knowledge and intellectual assets that tell them how to produce, trade, grow and react to environmental variations. Many organizations have become aware of the knowledge management (KM) discipline and understand that effective knowledge management can help them thrive and grow. A key success factor for organizations that are not already consciously practicing knowledge management is to develop a KM strategy for guidance and against which they can measure their progress. It is within the framework for the KM strategy that we discuss the functions and roles of a KM audit, and review the insights gained from performing KM audits for two large organizations, one of a state level social services organization, and the other of a multidivisional engineering company.
Presented at: Knowledge Management Challenge; 2003 Apr 3-4; Melbourne, Australia. p. 65-75.
title: Equipement rural (Ouezzane - Port-Lyautey - Rabat)
title: Equipement rural (Ouezzane - Port-Lyautey - Rabat)
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Rural (Le)
subject: Equipement rural

description: Cartographie
description: BESM-carto_1955-64-p591_64-05
description: 591
description: 64
description: Bulletin économique et social du Maroc
description: Source: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Source: Bulletin économique et social du Maroc
description: Source: Bulletin économique et social du Maroc (BESM) > BESM (Cartographie)
description: Relation: https://cinumed.mmsh.univ-aix.fr/idurl/1/81875
description: Coverage: Maroc
description: Coverage: Ouezzane
description: Coverage: XXe siècle
description: Temporal: XXe siècle
description: Bibliographic citation: « Equipement rural (Ouezzane - Port-Lyautey - Rabat) », In Bulletin économique et social du Maroc (BESM), n° 64, 1955
description: Provenance: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Provenance: https://cinumed.mmsh.univ-aix.fr/
Coordinating distributed group multiple criteria decision-making processes: preliminary results from a laboratory experiment
Creators: name: Monash University Research Repository
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: This paper presents an experimental study which explores the effects of different coordination methods on outcomes of distributed group decision-making processes. We adapt two methods: parallel and sequential, which represent loosely and tightly coupled coordination methods in terms of system structure imposed by GDSS on distributed group MCDM processes. The laboratory experiment with 84 senior undergraduate students shows that loosely coupled method yields higher users' satisfaction, while the tightly coupled method produces the better group decisions. These findings suggest that structures embedded in GDSS should be flexible.
Presented at: 7th International Conference of the International Society for Decision Support Systems: DSS in the Uncertainty of the Internet Age; 2003 Jul 13-16; Ustron, Poland. 22 leaves.
Breast cancer knowledge on line portal: an Intelligent decision support system perspective
Creators: name: Malhotra, Pooja
name: Burstein, Frada
name: Fisher, Julie
name: McKemmish, Sue
name: Anderson, June
name: Manaszewicz, Rosetta
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: Information provision over the Internet offers little by way of "intelligently" assisting users in retrieving personally relevant information. Web portals are envisaged as tools for matching users information needs in order to enhance their ability for decision-making. This paper looks at portals as a new type of intelligent decision support systems, which incorporate problem domain knowledge in order to improve efficiency in information provision. The main focus of the paper is in suggesting how certain characteristics of an intelligent decision support system can be implemented in a portal, which seeks to deliver personalised information to support efficient healthcare decision-making.
Presented at: 14th Australasian Conference on Information Systems; 2003 Nov 26-28; Perth, Australia. 11 leaves.
Pooja Malhotra, Frada Burstein, Julie Fisher, Sue McKemmish, June Anderson, Rosetta Manaszewicz © 2003. The authors assign to ACIS and educational and non-profit institutions a non-exclusive licence to use this document for personal use and in courses of instruction provided that the article is used in full and this copyright statement is reproduced. The authors also grant a non-exclusive licence to ACIS to publish this document in full in the Conference Papers and Proceedings. Those documents may be published on the World Wide Web, CD-ROM, in printed form, and on mirror sites on the World Wide Web. Any other usage is prohibited without the express permission of the authors.
Membrane condensation and curvature induced by SARS-CoV-2 envelope protein
Creators: name: Wölk, Christian
name: Shen, Chen
name: Hause, Gerd
name: Surya, Wahyu
name: Torres, Jaume
name: Harvey, Richard
name: Bello, Gianluca
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: The envelope (E) protein of SARS-CoV-2 participates in virion encapsulation and budding at the membrane of the endoplasmic reticulum Golgi intermediate compartment (ERGIC). The positively curved membrane topology required to fit an 80 nm viral particle is energetically unfavorable; therefore, viral proteins must facilitate ERGIC membrane curvature alteration. To study the possible role of the E protein in this mechanism, we examined the structural modification of the host lipid membrane by the SARS-CoV-2 E protein using synchrotron-based X-ray methods. Our reflectometry results on solid-supported planar bilayers show that E protein markedly condenses the surrounding lipid bilayer. For vesicles, this condensation effect differs between the two leaflets such that the membrane becomes asymmetric and increases its curvature. The formation of such a curved and condensed membrane is consistent with the requirements to stably encapsulate a viral core and supports a role for E protein in budding during SARS-CoV-2 virion assembly.
An approach to sensitivity analysis for data quality assessment in mobile decision-makingNew draft item
Creators: name: San Pedro, Jocelyn
name: Burstein, Frada
name: Zaslavsky, Arkady
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: In this paper, we propose a framework for mobile decision support that uses a dynamic context representation of quality of data to represent uncertainties in the mobile computing environment. We explore the notion of sensitivity analysis in these settings. Such analysis would be aimed at assessing the impact of con-text changes to decision outcomes. Our aim is to develop a decision support tool that intelligently adapts to changes in environment and sends alerts and advice on impact of these changes in decision outcomes. The paper describes how such system can be developed.
Presented at: 7th International Conference of the International Society for Decision Support Systems: DSS in the Uncertainty of the Internet Age; 2003 Jul 13-16; Ustron, Poland. 10 leaves.
Towards an organisational perspective to promote knowledge strategy
Creators: name: Gonçalo, Cláudio
name: Burstein, Frada
name: Lezana, Alvaro
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: This paper presents empirical research of an organisational perspective for promotion of knowledge strategy. Using this perspective as a guide, it presents an exploratory case study that examines how an organisation can be analysed for better promoting knowledge strategy. The chosen case is a firm daily involved with the design and development of new products and technologies. This research contributes to the wider knowledge management project, foregrounding intelligence and strategy as interactive concepts.
Presented at: 13th Australasian Conference on Information Systems; 2002 Dec 4-6, Melbourne, Australia. p. 255-265.
Rights: Cláudio Gonçalo, Frada Burstein and Alvaro Lezana © 2002. The authors assign to ACIS and educational and non-profit institutions a non-exclusive licence to use this document for personal use and in courses of instruction provided that the article is used in full and this copyright statement is reproduced. The authors also grant a non-exclusive licence to ACIS to publish this document in full in the Conference Papers and Proceedings. Those documents may be published on the World Wide Web, CD-ROM, in printed form, and on mirror sites on the World Wide Web. Any other usage is prohibited without the express permission of the authors.
Knowledge management obstacles in Australia
Creators: name: Zyngier, Suzanne
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: This paper presents a discussion of field research by survey of the range of obstacles to the effective implementation of knowledge management strategies in the Australian corporate environment. The paper provides background to the current study, refers to results and to further research possibilities. Previous research in the UK, in Europe, in Australasia and the USA has presented consistent findings of the obstacles to knowledge management implementation strategies. This Australian study reveals external obstacles to knowledge management that have not been found or discussed previously. These obstacles are outside the immediate control of the organisation itself, in that they are externally derived.
Presented at: 10th European Conference on Information Systems; 2002 Jun 6-8; Gdan'sk, Poland. 10 leaves.
Asset Backed Note Securitization Modelling
Creators: name: Lee, David
Publisher: name: unknown
Year: 2024
Subjects: subject: Asset-backed financing
subject: Derivative securities
subject: Derivative securities--Valuation

description: The model makes the assumption that the future values of these parameters will be unchanged until the final payment date. Subsequently, we perform a deterministic computation consisting of calculating the future cashflows in the waterfall and discounting them. We note that, in reality,
future parameter values are uncertain. Furthermore, the model does not account for a possible liquidity premium, credit and reinvestment risk associated with the notes.
Asset Backed Note Securitization Modelling
Creators: name: Lee, David
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Asset-backed financing
subject: Derivative securities
subject: Derivative securities--Valuation

description: The model makes the assumption that the future values of these parameters will be unchanged until the final payment date. Subsequently, we perform a deterministic computation consisting of calculating the future cashflows in the waterfall and discounting them. We note that, in reality, future parameter values are uncertain. Furthermore, the model does not account for a possible liquidity premium, credit and reinvestment risk associated with the notes.
NextGen Civil tiltrotor crashworthiness approaches
Creators: name: Di Palma, Luigi
name: Di Caprio, Francesco
name: Belardo, Marika
Publisher: name: Zenodo
Year: 2021

description: The presentation briefly describes the crashworthiness approaches followed in the collaborative projects T-WING and DEFENDER, funded by Clean Sky2 in the framework of EU Horizon2020 program.
description: Contribution presented in the EVTOL CRASHWORTHINESS WORKSHOP (https://nari.arc.nasa.gov/crashworthiness)
Enfoques de aprendizaje y rendimiento académico universitario en Ecuador
Creators: name: Catucuago, Dennys
Publisher: name: Humanities Commons
Year: 2024

description: La Universidad ecuatoriana está transformando su enfoque educativo para tratar al estudiante como un sujeto activo en su aprendizaje. Este estudio analiza cómo los enfoques de aprendizaje afectan el rendimiento académico de los estudiantes de la Facultad de Ciencias Agrícolas de la Universidad Central del Ecuador.
Knowledge management in the financial services sector: understandings and trends in Australia
Creators: name: Burstein, Frada
name: Zyngier, Suzanne
name: Rateb, Zohdy
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: Knowledge management in a difficult concept but one that is fairly well understood by the Australian financial services sector. These organisations are in the process of implementing some form of strategy to manage knowledge. Many organisations that do not claim to have a strategy to manage knowledge are implementing practical steps to do so. The results of this research are compared with previous research in this sector in the UK and Europe that have shown different understandings and strategies to manage it.
Presented at: 3rd European Conference on Knowledge Management; 2002 Sep 24-25; Dublin, Ireland. p. 113-124.
FROM DIGITAL TECHNOLOGIES IN THE EDUCATIONAL SYSTEM PROSPECTS
Creators: name: Jumamuratova, Gulziba
Publisher: name: Zenodo
Year: 2024

description: In this article, the priority areas of development of the educational process are identified based on the application of digital technologies in the higher education system of our republic, the analysis of their capabilities. Also in the field of education through the study, systematization and generalization of the existing practice in drawing scientifically based conclusions on the introduction of digital technologies in higher education  not only in terms of its important place and in what form it is introduced suggestions are given.
Building a user sensitive intelligent portal to breast cancer knowledge to meet diverse information needs
Creators: name: Fisher, Julie
name: Burstein, Frada
name: McKemmish, Sue
name: Manaszewicz, Rosetta
name: Anderson, June
name: Williamson, Kristy
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: The Internet provides access to a plethora of information, with health information being no exception. Portals for guiding users seeking health knowledge are proliferating. A major challenge in their development is filtering the information available in a user-sensitive way. The Breast Cancer Knowledge Online (BCKOnline) project addresses the challenge of meeting the diverse information needs of women with breast cancer and their families through the provision of timely, relevant and reliable information to support decision-making. This paper focuses on how the outcomes of user needs analysis and user-aware resource description will feed into building an intelligent portal prototype to breast cancer knowledge.
Presented at: 13th Australasian Conference on Information Systems; 2002 Dec 4-6; Melbourne, Australia. p. 685-697.
An accounting framework for implementing India’s NDCs and reporting the capacity building needs in the context of the Paris rulebook
Creators: name: Prusty, Debasish
name: Garg, Amit
name: Solanki, Umesh
name: Maheshwari, Jyoti
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: The purpose of this paper is to suggest an accounting framework for India for implementation of its nationally determined contributions (NDCs) and design the appropriate modality for reporting its capacity building needs and priorities in a manner that is in consonance with the provisions of the Paris Rule book from the perspective of a developing country. The suggested accounting methodology considers India’s national greenhouse gas (GHG) inventory and climate mitigation policies. The Key Category Analysis concept of the Intergovernmental Panel on Climate Change for accounting GHG inventory estimation at the national level is used to identify and rank the key inventory categories for India. Accounting of various national level mitigation policies is undertaken by assessing their impact on the key categories, subsequently recognizing ‘Key Policies’ in accordance with the provisions of the Paris rulebook. ‘Key Policies’ are found to have a definite role in driving the progress of implementation of NDCs. The study recommends a modality that developing countries can use to report their needs for capacity building support for full implementation of their ‘key policies’ while accounting their future NDCs, using the flexibilities provided under the Paris Rule book.
Climate shocks, vulnerability, resilience and livelihoods in rural Zambia
Creators: name: Ngoma, Hambulo
name: Finn, Arden
name: Kabisa, Mulako
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Neuroscience
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Computational Biology

description: Climate and weather shocks pose risks to livelihoods in Southern Africa. We assess the extent to which smallholders are exposed to climate shocks in Zambia and how behavioural choices influence the negative effects of these shocks on vulnerability and resilience. We use household data from the nationally representative Rural Agricultural Livelihoods Survey and employ an instrumental variable probit regression model to control for the endogeneity of key choice variables. There are four main findings. First, droughts are the most prevalent climate shock faced by rural smallholder farmers in Zambia, but the extent of exposure differs spatially, with the Southern and Western Provinces being the hardest hit. Nationally, 76% of all smallholder farmers are vulnerable and only 24% are resilient, with female households most vulnerable. Second, increased climate shocks correlate with both increased vulnerability and reduced resilience, with short- and long-term deviations in seasonal rainfall worsening vulnerability and resilience. Third, higher asset endowments and education are correlated with reduced vulnerability and increased resilience. And last, climate-smart agricultural practices significantly improve household resilience. These findings imply a need to support scaling of climate-smart agricultural technologies and to invest in risk mitigation strategies such as weather-indexed insurance and targeted social cash transfers.
A task-based framework for supporting knowledge work practices
Creators: name: Burstein, Frada
name: Linger, Henry
Publisher: name: Monash University
Year: 2016
Subjects: Uncategorized

description: This paper examines the role of knowledge management and knowledge management systems (KMS) for supporting knowledge work. We argue that an organization benefits from knowledge management systems when it is focused on a specific task as knowledge is always task-specific and situated in the specific context in which the task is instantiated. Providing support for knowledge work at the task level complements the work practices of actors performing the task. Such a system supports extended functionality such as reasoning, memory aids, and explanation facilities and learning capability, amongst other facilities. A system with such capability can be defined Knowledge Work Support System. The paper discusses the task-based knowledge management approach at individual and organisational levels and describes its application to the strategy development at an International Bank.
Presented at: 3rd European Conference on Knowledge Management; 2002 Sep 24-25; Dublin, Ireland. p. 100-112.
[Enveloppe d'un courrier adressé à Yolanda Huerga Cedeño-01]
Creators: name: Manuel, Vázquez Portal
name: Vázquez Portal, Manuel
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: Prison de Boniato

description: Destinataire : Huerga Cedeño, Yolanda
description: Notes : Absence dans le fonds d'archives de la lettre de Vázquez Portal à son épouse correspondante à cette enveloppe. Courrier envoyé depuis la Prison de Boniato, 'Celda n° 9. Boniatico'. Dates illisibles (année) sur les cachets de la poste au recto et au verso. Adresse figurant sur l'enveloppe : 'Edificio 979 apto 14 – Zona 24. Alamar – Habana del Este – Ciudad de la Habana – Cuba'.
description: Source: Cote : MVP-B-2003-00-07
description: Source: Localisation du document : États-Unis, Miami (Floride)
description: created: 2003/2004
title: A new universal model explaining fracture-trace length distributions
Creators: name:  Krumbholz ,   Michael
name:  Hieronymus ,   Christoph
name:  Kamm ,   Jochen
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Fracture dimensions largely control rock properties like strength and permeability. Thus, knowing their statistical distributions is of great importance in many applied fields of the geosciences e.g., in geothermics, mineral exploration, and hydrology. They are also of academic interest since the statistical distribution of fracture dimensions (length, height, width) might provide inside in fracture formation mechanisms. However, in the vast majority of cases this information is derived from observations in 2 dimensions, i.e., instead of a fractures length, not the true length, but a fractures-trace length (FTL) is measured. In conclusion information or even estimates about the length of an individual fracture and about the statistical distribution of fracture lengths of a fracture population are not possible. We analyze the statistical distributions of FTLs mapped at 3 different scales under the application of different mapping schemes that are commonly used to account for the limitations that are unavoidable, when recording fracture lengths in 2 dimensions. In our study we test how well powerlaw-, exponential-, Weibull-, lognormal-, and log-logistic distributions fit the FTL data. Our results show that FTLs are lognormal distributed independent of scale and mapping scheme and that the parameters of the lognormal distributions reflect outcrop quality and dimension. In addition, we provide a comprehensive model that explains the observed lognormal distributions of FTLs. This model is based on random restrictions that control the observable FTLs and includes human error and bias in mapping.
Ultrasonography predicts achievement of Boolean remission after DAS28-based clinical remission of rheumatoid arthritis
Creators: name: Yoshimi, Ryusuke
name: Maasa Hama
name: Minegishi, Kaoru
name: Kishimoto, Daiga
name: Watanabe, Toshiyuki
name: Reikou Kamiyama
name: Kirino, Yohei
name: Asami, Yukiko
name: Ihata, Atsushi
name: Tsunoda, Shinichiro
name: Ueda, Atsuhisa
name: Takeno, Mitsuhiro
name: Ishigatsubo, Yoshiaki
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Objectives. To determine whether ultrasonography (US) predicts Boolean remission in rheumatoid arthritis (RA) patients who had achieved disease activity score in 28 joints (DAS28)-based remission criteria. Methods. Thirty-one RA patients in DAS28-based clinical remission were recruited. US semiquantitatively determined Gray scale (GS) and power Doppler (PD) signal scores in the bilateral wrists and all metacarpophalangeals and proximal interphalangeals. Total GS score and total PD score were calculated as the sum of individual scores for each joint. Results. Among 22 RA patients, who maintained DAS28 remission for 2 years, 16 met Boolean remission criteria at the end of study. Both total GS and total PD scores at baseline were significantly lower in Boolean remission group than non-remission group. There was no significant difference in other baseline parameters, including duration of disease, duration of remission, mTSS, and disease activity composite parameters between the two groups. Among the factors for Boolean remission criteria at 2 years, patient global assessment score was associated with total GS score at the entry, while swollen joint count was related to total PD score. Conclusions. Null or low grade of GS and PD findings in US are associated with achieving Boolean remission. Thus, US is essential for assessment and prediction of “deeper remission” of RA.
Owen Jones, The Establishment: And How They Get Away With It (2015)
Creators: name: Akyildiz, Sevket
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Great Britain
subject: Politics and government
subject: Neoliberalism
subject: Ideology

description: Eurasia Studies Society of Great Britain & Europe Journal, Book Review, Vol. 6. No. 1. 2023: 8-15. What do the British mean by the term ‘The Establishment’? How does it function? Is it a collection of individuals who know each other or a network of interconnected groups based on power and privilege? How does it justify its behaviour? Do its group members share an ideology? Owen Jones’s The Establishment: And How They Get Away With It seeks to answer these questions and explain how the neoliberal Establishment threatens British democracy.
title: The European continental crust through detrital zircons from modern rivers: biasing effects in the detrital zircon record
Creators: name:  Castillo ,   Paula
name:  Bahlburg ,   Heinrich
name:  Fernández ,   Rodrigo
name:  Fanning ,   Mark
name:  Berndt ,   Jasper
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: We present U-Pb, Lu-Hf, and O isotopic data, as well as size-shape data for approximately 3700 detrital zircons from 15 European rivers. In combination with geomorphological information for each river basin (area, drainage length, and hypsometric curves), we evaluate the representativeness and biases affecting such datasets. The new data allow us to demonstrate that the detrital zircon record from major rivers represents all relevant geological events in Europe at the continental scale, with detrital zircon ages ranging from Cenozoic to Archean. Several age peaks can be linked to different orogenic cycles and the formation of supercontinents such as Pangea and the Variscan Orogen, the largest episode of crustal reworking in Europe. These Variscan detrital zircons occur in all rivers, but Permian post-Variscan were only found in the Po (with significant crustal contamination) and Glomma rivers (with radiogenic and mantle-like signatures). Other important age clusters are the Alpine and post-Alpine Cenozoic 25-40 Ma and juvenile 0.2-10 Ma, the Caledonian 400-490 Ma, and the Avalonian-Cadomian 540-650 Ma. Detrital zircons of 930-1170 Ma and 1400-1700 Ma are significant in Scandinavia, as well as ca. 1850 and 2500-2900 Ma in east Europe. Despite the good representation of the different geological events in Europe, this does not occur when analyzing detrital zircon at smaller scales (i.e. the basin scale). The presence, importance, and proportions of peaks are strongly dominated by factors such as fertility, zircon-size-shape, and other geomorphological aspects. Excluding fertility, these factors alone can bias the proportion of peaks by up to 10%.
A comparison of incidence and risk factors for serious adverse events in rheumatoid arthritis patients with etanercept or adalimumab in Korea and Japan
Creators: name: Cho, Soo-Kyung
name: Sakai, Ryoko
name: Nanki, Toshihiro
name: Koike, Ryuji
name: Watanabe, Kaori
name: Yamazaki, Hayato
name: Nagasawa, Hayato
name: Tanaka, Yoshiya
name: Nakajima, Atsuo
name: Yasuda, Shinsuke
name: Ihata, Atsushi
name: Ezawa, Kazuhiko
name: Soyoung Won
name: Chan-Bum Choi
name: Yoon-Kyoung Sung
name: Kim, Tae-Hwan
name: Jae-Bum Jun
name: Yoo, Dae-Hyun
name: Miyasaka, Nobuyuki
name: Sang-Cheol Bae
name: Harigai, Masayoshi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: 60506 Virology

description: Objective. To compare the incidence and risk factors of serious adverse events (SAEs) in rheumatoid arthritis (RA) patients treated with etanercept (ETN) or adalimumab (ADA) between Korean and Japanese registries. Methods. We recruited 416 RA patients [505.2 patient-years (PYs)] who started ETN or ADA from Korean registry and 537 RA patients (762.0 PY) from Japanese registry. The patient background, incidence rate (IR) of SAE in 2 years, and risk factors for SAEs were compared. Results. Korean patients were younger and used more nonbiologic DMARDs, higher doses of methotrexate, and lower doses of prednisolone (PSL). The IR of SAEs (/100 PY) was higher in the Japanese registry compared to the Korean [13.65 vs. 6.73]. In both registries, infection was the most frequently reported SAE. The only significant risk factor for SAEs in Korean registry was age by decade [1.45]. In Japanese registry, age by decade [1.54], previous use of nonbiologic DMARDs ≥ 4 [1.93], and concomitant use of oral PSL ≥ 5 mg/day [2.20] were identified as risk factors for SAEs. Conclusions. The IR of SAE in Japan, especially infection, was higher than that of Korea, which was attributed to the difference of demographic and clinical characteristics of RA patients and treatment profiles.
Social Norms and Obligation: Rescuing the Joint Commitment Account
Creators: name: Stahl, Titus
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Social norms

description: In Morality and Socially Constructed Norms, Laura Valentini argues that moral obligations to respect social norms can be explained without invoking the concept of ‘joint commitment.’ Her resulting account is, in one important sense, individualistic, and therefore struggles to account for widely held intuitions about the normative significance of social norms. I argue that we can rescue the notion of joint commitment from Valentini’s objections, and incorporate it into a version of her account that preserves its insights.
title: Crystallisation sequence of a REE-rich carbonate melt: an experimental approach
Creators: name:  Mollé ,   Valentin
name:  Gaillard,   Fabrice
name:  Nabyl ,   Zineb
name:  Tuduri ,   Johann
name:  Di Carlo ,   Ida
name:  Erdmann ,   Saskia
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Carbonatites host the main REE deposits in the world, with bastnaesite being the main REE-bearing mineral of interest. However, the nature of the enrichment process, magmatic vs hydrothermal, is still debated. This study aims to experimentally determine the behaviour of REE elements during carbonatite crystallisation, and if bastnaesite can be directly crystallised from a carbonate melt. Crystallisation experiments have been done from 900 to 600°C at 1 kbar on a REE-rich calciocarbonatitic composition. Calcite (Ca,REE)CO3 is the dominant magmatic mineral, so the residual melt evolves toward natrocarbonatitic compositions as crystallisation proceeds. A small amount of britholite (REE,Ca)5((Si,P)O4)3(OH,F) is observed at high temperatures and is replaced by phlogopite KMg3(AlSi3O10)(OH)2 and apatite (Ca,REE)5(PO4)3(F,OH) at T < 650°C. A small amount of pyrochlore (Ca,Na,REE)2Nb2O6(OH,F) is observed at T < 700°C. No bastnaesite has been found in any crystallisation experiment. We thus performed a bastnaesite saturation experiment at 600°C. The melt saturated with bastnaesite however contains 20 wt% of REE: such high value implies that magmatic saturation of bastnaesite is unlikely to happen in nature. F, Cl and water decrease the temperature of calcite saturation, allowing the system to crystallise at lower temperatures. REE are slightly incompatible with calcite, especially at low temperatures. The residual carbonate melt is thus enriched as crystallisation proceeds. Finally, we collected textural and chemical evidence suggesting the presence of a Na,Cl,REE-rich fluid at high temperatures and under hydrous conditions. Such Na,Cl,REE-rich fluids may play a critical role in the remobilisation of REE and the bastnaesite crystallisation during subsolidus reactions.
A nationwide survey on the epidemiology and clinical features of eosinophilic granulomatosis with polyangiitis (Churg-Strauss) in Japan
Creators: name: Ken-Ei Sada
name: Amano, Koichi
name: Ritei Uehara
name: Yamamura, Masahiro
name: Arimura, Yoshihiro
name: Nakamura, Yoshikazu
name: Makino, Hirofumi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objective. We conducted a cross-sectional nationwide survey to determine eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) prevalence and clinical features in Japan. Methods. Data for EGPA patients in 2008 were collected from 1,564 hospitals. In total, 965 patients were reported from 365 departments. In a second survey, clinical data for 473 patients were obtained. Results. We estimated that 1,866 (95% CI: 1,640–2,092) patients have EGPA in Japan (prevalence, 17.8/1,000,000). Of the 473 patients in the second survey, 315 fulfilled American College of Rheumatology (ACR) criteria or Lanham's criteria for EGPA. The mean age (± SD) of the 315 at onset was 55 ± 14 years, male to female ratio 1:2. 93% of patients had neurological manifestations, which were the organ system most frequently involved. Among 277 patients tested for myeloperoxidase (MPO)-/p anti-neutrophil cytoplasmic antibody (ANCA), 139 (50%) were positive, while only 6 of 238 were positive for proteinase3 (PR3)-/cANCA. MPO-ANCA-positive patients had renal involvement, mucous membrane or ophthalmological symptoms, and ENT symptoms more frequently, whereas cutaneous lesions and cardiovascular involvement were less common. Conclusion. The prevalence of EGPA and the frequency of MPO-/p-ANCA-positivity in Japanese EGPA patients were mostly similar to those of Western countries. However, female predominance and a high frequency of neurological manifestations characterized Japanese patients.
York.Classroom.sept15-2016.cvs.csv
Creators: name: Hosseini, Kiana Malak
Publisher: name: figshare
Year: 2016
Subjects: subject: 60202 Community Ecology (excl. Invasive Species Ecology)
subject: FOS: Biological sciences

description: Method: A group of 4 members was assembled in a York university (in Toronto, Canada) classroom to conduct a verbal survey. Each member went to a different group containing 4 or 5 individuals and asked each individual to self identify both their hair color and their gender. Once each member collected the desired information, the data was filled into a table containing information about the hair color and gender of 24 individuals.
Hypothesis: Female hair color varies more than male hair color.
Prediction:1.Female hair color varies more due to there being stigma behind idea.2. Female and male hair color variety is the same, due to social changes, and society becoming more accepting to peoples way of expression and their choices.

Group members: Michelle Urman, Brenda Espin, Shunelle Prasad
Collective victim beliefs in the aftermath of historical trauma and their effects on psychological well-being: Initial findings among the Polish diaspora in the United States
Creators: name: Skrodzka, Magdalena
name: Vollhardt, Johanna Ray
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: Historical trauma impacts the affected groups long after traumatic events. In response to such experiences, people may make sense of this history through collective victimisation beliefs that compare their ingroup's experiences to outgroups' experiences. Additionally, they may perceive these collective experiences as central to their self and group identity, or distance themselves from them. How-ever, it is not yet well understood how distinct beliefs about historical trauma are linked to psychological well-being. The present study examined this question among the Polish diaspora in the United States (N = 280). Mediation analyses showed a negative indirect effect of exclusive victim beliefs and centrality of collective victimisation on psychological well-being, while inclusive victim beliefs and decentring collective victimisation had positive indirect effects on psychological well-being. Structural equation modelling examining all collective victim beliefs simultaneously highlighted historical victimisation as identity content (a subscale of centrality of collective victimisation) as a particularly important predictor of psychological well-being, through historical trauma emotions. Overall, in line with appraisal theory, these findings suggest that how a group's historical victimisation is construed is linked to emotional processes and can predict psychological well-being. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement.
title: Identification of the diagenetic sedimentary environment and hydrothermal fluid fluxes in Southern Ocean sediments (IODP Exp 382) using B, Si and Sr isotopes in interstitial waters
Creators: name:  Mollé ,   Valentin
name:  Geilert ,   Sonja
name:  Kenlee ,   Bridget
name:  Wallmann ,   Klaus
name:  Seki ,   Osamu
name:  Hwan ,   Ji-Hwan
name:  Weber ,   Michael E
name:  Raymo ,   Maureen
name:  Peck ,   Victoria L.
name:  Williams ,  Trevor
name:  Scholz ,   Florian
name:  382 Scientists ,   Expedition
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: During IODP Expedition 382, two sites were drilled at 53.2°S at the northern edge of the Scotia Sea and three sites at 57.4°–59.4°S in the southern Scotia Sea within the Atlantic sector of the Southern Ocean. Sediments at both locations alternate between dominant terrigenous components during glacials and dominant biogenic components, carbonate at the northerly sites and opal in the southern Scotia Sea, during interglacials. Here we constrain the geochemical environment in interstitial waters using the boron (δ11B), silicon (δ30Si) and 87Sr/86Sr isotopic composition. Interstitial water δ11B and δ30Si decrease in the uppermost tens of meters downcore, most likely due to in situ weathering processes preferentially releasing light isotopes to interstitial waters. This process is partly also reflected by strongly increasing alkalinities in this depth interval. While δ30Si at all sites increase already at shallow sediment depth where organic matter degradation is intense, δ11B remain relatively low beyond the lower boundary of elevated dissolved phosphate concentrations at every core site. Below this depth δ11B follow isotopic trends seen in δ30Si towards heavy compositions, presumably because of dominating secondary clay formation. Interstitial waters obtained as deep as 550 and 670 mbsf from the southern Scotia Sea sites reveal an increasing importance of off-axis hydrothermal fluids within the basement underlying the sediments. This feature is detectable by lowest 87Sr/86Sr alongside lowest Mg/Sr and strongly decreasing δ11B at the lower end of the cores. Our key aim is to illustrate the dominant diagenetic process at each depth downcore, and how to identify these.
Microwave-assisted synthesis of benzoxazinediones under solvent-free conditions
Creators: name: Sarmiento-Sánchez, Juan I.
name: Ochoa-Terán, Adrián
name: Picos-Corrales, Lorenzo A.
name: Osuna-Martínez, Lorenzo U.
name: Montes-Ávila, Julio
name: Bastidas-Bastidas, Pedro
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: Benzoxazinediones exhibit potential as versatile synthons in the synthesis of wide variety of heterocyclic compounds with biological activity. In this work, an efficient and eco-friendly one-step synthesis of benzoxazine-2,4-diones from phthalic anhydrides derivatives and trimethylsilyl azide using the microwave technique was developed and compared with conventional heating. Microwave irradiation plays a critical role in driving the reaction and providing access to products and/or regioisomers not available from conventional heating. Thus, the regioselectivity of the reaction may be modulated by the irradiation time. Depending on the method employed the benzoxazinediones were isolated with yields in the range of 30–90%.
Yegorov et al GCE 2014.pdf
Creators: name: Yegorov, Sergey
Publisher: name: figshare
Year: 2016
Subjects: subject: 60409 Molecular Evolution
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: This is a draft of a manuscript published in the General and Comparative Endocrinology Journal.