cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Subgruppenanalyse zur Studie 65 plus
Creators: name: Niemann, Bettina
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2018
Subjects: subject: 610

description: Trotz höchster Inzidenzrate jenseits des 70. Lebensjahres sind gerade ältere Patienten in großen Studien zur Behandlung des lokal fortgeschrittenen oder metastasierten Bronchialkarzinoms oftmals unterrepräsentiert. Gezielt bei Patienten älter als 65 Jahre zeigte die Studie 65 plus im Vergleich der Wirksamkeit einer Behandlung mit Pemetrexed und Bevacizumab mit oder ohne Carboplatin ein signifikant höheres progressionsfreies Überleben ohne Auswirkung auf das Gesamtüberleben für die mit Carboplatin behandelten Patienten. Die vorliegende Dissertation untersuchte die Effektivität beider Therapien auf die gebildeten Subgruppen bezüglich Alter, Geschlecht, Raucherstatus und Erhaltungstherapie. Die Ergebnisse zeigen, dass bei bestimmten Patientengruppen die Wahl des Therapieregimes sowie die applizierte Gesamtdosis der Medikation eine entscheidende Rolle in der Behandlung des Bronchialkarzinoms spielt. Zukünftig sind dennoch weitere Untersuchungen mit größeren Patientenzahlen notwendig, um die genannten positiven Effekte zu bestätigen und individuelle palliative Therapiekonzepte für ältere Patienten außerhalb der Target- oder Immuntherapie zu entwickeln.
description: Despite the highest incidence rate over the age of 70 older patients are often underrepresented in large studies on the treatment of advanced or metastatic lung cancer. Targeted patients older 65 years the study 65 plus pointed in comparison of effectiveness between a treatment with Pemetrexed and Bevacizumab with or without Carboplatin a significant higher progression free survival for patients treated with Carboplatin. This dissertation investigated the effectiveness of both therapies regarding age, sex, smoking status and maintenance therapy. The results show that in certain patient groups the choice of therapy regimen and the total dose of medication administered play a crucial role in the treatment of bronchial carcinoma. In the future, however, further examinations with larger numbers of patients will be necessary to confirm the mentioned positive effects and to develop individual palliative therapy concepts for older patients outside the target or immunotherapy.
title: Higgs boson potential at colliders: status and perspectives
Creators: name:  Di Micco, Biagio
name: Vernier, Caterina
name: Mazzitelli, Javier
name: Gouzevitch, Maxime
Publisher: name: Roma TrE-Press
Year: 2020

description: Questo documento riassume lo stato attuale degli ricerche studi, teorici e sperimentali,  sulla produzione di coppie di bosoni di Higgs, e sui vincoli, sia diretti che indiretti, al valore del termine di auto-interazione del bosone di Higgs, con l’intento di servire da referenza per i prossimi anni. Il documento discute lo stato degli studi teorici, includendo le più recenti stime della sezione di produzione di coppie di bosoni di Higgs, sviluppi sulle teorie di campo efficaci, e studi su specifici scenari di nuova fisica che possono contribuire alla produzione di due bosoni di Higgs. Sono presentati i più recenti risultati sperimentali sulle ricerche di coppie di bosoni di Higgs e sui limiti diretti e indiretti al termine di auto-interazione, ottenuti al Large Hadron Collider di Ginevra, con una panoramica delle tecniche sperimentali. Infine, sono discusse le capacità dei collisionatori futuri di determinare il termine di auto-interazione del bosone di Higgs.  Questo lavoro è iniziato come raccolta di contributi della conferenza  “Di-Higgs ai Colliders”, che ha avuto luogo a Fermilab dal 4 al 9 settembre 2018,  ma gli argomenti discussi vanno al di là di quelli presentati alla conferenza,  includendo ulteriori sviluppi.
Molecular dynamics simulations of the contact angle between water droplets and graphite surfaces
Creators: name: Sergi, Danilo
name: Scocchi, Giulio
name: Ortona, Alberto
Publisher: name: arXiv
Year: 2012
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Wetting is a widespread phenomenon, most prominent in a number of cases, both in nature and technology. Droplets of pure water with initial radius ranging from 20 to 80 [Å] spreading on graphitic surfaces are studied by molecular dynamics simulations. The equilibrium contact angle is determined and the transition to the macroscopic limit is discussed using Young equation in its modified form. While the largest droplets are almost perfectly spherical, the profiles of the smallest ones are no more properly described by a circle. For the sake of accuracy, we employ a more general fitting procedure based on local averages. Furthermore, our results reveal that there is a possible transition to the macroscopic limit. The modified Young equation is particularly precise for characteristic lengths (radii and contact-line curvatures) around 40 [Å].
description: Revised and extended version; http://dx.doi.org/10.1016/j.fluid.2012.07.010
Hand-eye coordination for grasping moving objects
Creators: name: Allen, Peter K.
name: Timcenko, Aleksandar
name: Yoshimi, Billibon
name: Michelman, Paul
Publisher: name: Columbia University
Year: 1991
Subjects: Robotics

description: Most robotic grasping tasks assume a stationary or fixed object. In this paper, we explore the requirements for grasping a moving object. This task requires proper coordination between at least 3 separate subsystems: dynamic vision sensing, real-time arm control, and grasp control. As with humans, our system first visually tracks the object's 3-D position. Because the object is in motion, this must be done in a dynamic manner to coordinate the motion of the robotic arm as it tracks the object. The dynamic vision system is used to feed a real-time arm control algorithm that plans a trajectory. The arm control algorithm is implemented in two steps: 1) filtering and prediction, and 2) kinematic transformation computation. Once the trajectory of the object is tracked, the hand must intercept the object to actually grasp it. We present 3 different strategies for intercepting the object and results from the tracking algorithm.
Tunable singlet-triplet splitting in a few-electron Si/SiGe quantum dot
Creators: name: Shi, Zhan
name: Simmons, C. B.
name: Prance, J. R.
name: Gamble, John King
name: Friesen, Mark
name: Savage, D. E.
name: Lagally, M. G.
name: Coppersmith, S. N.
name: Eriksson, M. A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We measure the excited-state spectrum of a Si/SiGe quantum dot as a function of in-plane magnetic field, and we identify the spin of the lowest three eigenstates in an effective two-electron regime. The singlet-triplet splitting is an essential parameter describing spin qubits, and we extract this splitting from the data. We find it to be tunable by lateral displacement of the dot, which is realized by changing two gate voltages on opposite sides of the device. We present calculations showing the data are consistent with a spectrum in which the first excited state of the dot is a valley-orbit state.
description: 4 pages with 3 figures
Costs of Producing Milk, 1975-84
Creators: name: Betts, Carolyn
name: Betts, Carolyn
Publisher: name: Unknown
Year: 1987
Subjects: subject: Livestock Production/Industries
subject: Production Economics
subject: Research Methods/ Statistical Methods
subject: Cost of production
subject: costs and returns

description: Costs of producing milk rose 53 percent in 1975-84 to $13.57 per hundredweight (cwt). Cash (out-of-pocket) costs rose 56 percent to $10.64 per cwt. Cash receipts, measuring gross production value, peaked in 1981 at $14.94 per cwt compared with $9.23 in 1975. Production costs in the Pacific region were more than $1 per cwt lower than costs in other regions every year during 1975-84. Appalachia and the Corn Belt had the highest costs. In 1983, the Economic Research Service (ERS) revised its cost-of-production estimating procedures and cost-and-return budget formats to incorporate new concepts and methodologies. This report describes those revisions and re-estimates milk production costs for 1975-80 using the new methods and formats to provide comparable estimates for 1975-84.
Thinning and prescribed fire for ecosystem restoration in Rocky Mountain forests of British Columbia : changes in physical, chemical and biological properties of forest floors and soil
Creators: name: Switzer, Joshua M.
Publisher: name: University of British Columbia
Year: 2011

description: Prevention of uncontrolled wildfire and restoration of Rocky Mountain forests can be accomplished through ecosystem restoration practices such as thinning followed by prescribed fire. The objective of this study is to determine how much thinned fuel can be left on the ground without causing fire temperatures high enough to impair soil physical, chemical and biological properties. I assess the effects of different fuel loadings on soil properties (forest floor depth, soil pH, carbon and nutrient levels, and soil bacteria and fungal communities) during the first year after fire and explore relationships among fuel loadings, fire temperatures and indicators of soil health. Five fuel management treatments were assessed: large piles, small piles, areas of cut-and-leave, deep litter and an unburned control. In all burned treatments, fuel loadings were greatly reduced and maximum temperatures at the forest floor surface ranged from 60 to 850°C. Temperatures were over 300°C for over 3 hours in the large-pile treatment but were lower and of shorter duration in the small-pile and cut-and-leave treatments. The deep-litter treatment had temperatures above 200°C for over 2 hours and complete combustion of the forest floor occurred. The low moisture content and resulting consumption of the forest floor in the deep-litter treatment resulted in the largest negative impacts on soil chemical and microbiological properties, while few significant differences were evident among the other treatments. Higher nitrate availability and significant increases in pH were found in the forest floors of burned plots and in the mineral soil of the deep-litter treatment. Microbial abundance did not recover to pre-fire levels in any burned treatments after one year, which may be attributed to the persistence of significant increases in pH.
Trajectory filtering and prediction for automated tracking and grasping of a moving object
Creators: name: Allen, Peter K.
name: Timcenko, Aleksandar
name: Yoshimi, Billibon
name: Michelman, Paul
Publisher: name: Columbia University
Year: 1992
Subjects: Robotics

description: The authors explore the requirements for grasping a moving object. This task requires proper coordination between at least three separate subsystems: real-time vision sensing, trajectory-planning/arm-control, and grasp planning. As with humans, the system first visually tracks the object's 3D position. Because the object is in motion, this must be done in real-time to coordinate the motion of the robotic arm as it tracks the object. The vision system is used to feed an arm control algorithm that plans a trajectory. The arm control algorithm is implemented into two steps: filtering and prediction and kinematic transformation computation. Once the trajectory of the object is tracked, the hand must intercept the object to actually grasp it. Experimental results are presented in which a moving model train was tracked, stably grasped, and picked up by the system.
Modeling dynamic uncertainty in robot motions
Creators: name: Timcenko, Aleksandar
name: Allen, Peter K.
Publisher: name: Columbia University
Year: 1993
Subjects: Robotics

description: A method for modeling uncertainties that exist in a robotic system, based on stochastic differential equations, is presented. The use of such a model permits the capture in an analytical structure of the ability to properly express uncertainty within the motion descriptions and the dynamic, changing nature of the task and its constraints. With respect to the dynamic nature of robotic motion tasks, the model of the environment uncertainty proposed is dynamic rather than static. The amount of knowledge about the environment is allowed to change as the robot moves. These results suggest that computational models traditionally found in the lower levels in robot systems may have application in the upper planning levels as well. Some experimental results using the model are presented.
Unfinished History and Paradoxes of Quantum Potential. I. Non-Relativistic Origin, History and Paradoxes
Creators: name: Tagirov, E. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The first of the two related papers analising and explaining the origin, manifestations and parodoxical features of the quantum potential (QP) from the non-relativistic and relativistic point of view. QP arises in the quantum Hamiltonian, under various procedures of quantization of the systems whose Hamilton functions are the positive-definite quadratic forms in momenta with coefficients depending on the coordinates in (n-dimensional) configurational space (natural systems). Owing to the Riemannian structure thus introduced in the space, the result of quantization is considered as quantum mecanics (QM) of a particle. Contradiction of QP to the Principles of General Covariance and Equivalence is discussed. It is found that actually the historically first Hilbert space based quantization by E. Schrödinger (1926), after revision in the modern framework of QM, also leads to QP in the form that B. DeWitt had been found 26 years later. Efforts to avoid QP or reduce its drawbacks are discussed. The general conclusion is that some form of QP and a violation of the principles of general relativity induced by it are apparently inevitable in the non-relativistic QM. It is shown also that Feynman quantization singles out two versions of QP, which both determine two bi-scalar propagators which fix two different algorithms of path integral calculation. In the accompanying paper under the same general title and the subtitle "The Relativistic Point of View", relation of the non-relativistic QP to the quantum theory of the scalar field non-minimally coupled to the curved space-time metric is considered.
description: 16 pages; tagirov@theor.jinr.ru ; based on the plenary talk at the A. Z. Petrov Centenary Memorial International Symposium, 1-7.11.2010, Kazan, Russia; minor corrections and improvements in the text; a reference added
The STRONGMAN Architecture
Creators: name: Keromytis, Angelos D.
name: Ioannidis, Sotiris
name: Greenwald, Michael B.
name: Smith, Jonathan M.
Publisher: name: Columbia University
Year: 2003
Subjects: Computer science

description: The design principle of restricting local autonomy only where necessary for global robustness has led to a scalable Internet. Unfortunately, this scalability and capacity for distributed control has not been achieved in the mechanisms for specifying and enforcing security policies. This shortcoming must be overcome if end-to-end security mechanisms (such as IPsec or TLS) are to ever replace solutions of short-term convenience such as firewalls. The STRONGMAN (for Scalable Trust Of Next Generation Management) system offers three new approaches to scalability, applying the principle of local policy enforcement complying with global security policies. First is the use of a compliance checker to provide great local autonomy within the constraints of a global security policy. Second is a mechanism to compose policy rules into a coherent enforceable set, e.g. at the boundaries of two locally autonomous application domains. Third is the "lazy instantiation" of policies to reduce the amount of state that enforcement points need to maintain. We demonstrate the use of these approaches in the design, implementation, and measurements of a distributed firewall. Our experiments show that, under certain circumstances, performance can improve over the traditional-firewall approach.
Submission on a proposed Data Act for the European Union from the perspective of open energy system analysis / 2 — Release 02
Creators: name: Morrison, Robbie
Publisher: name: Zenodo
Year: 2021
Subjects: european-union-legislation

description: A second submission in response to the "Inception impact assessment: Data Act" document from the European Commission and the associated public consultation. This iteration has just one submitter. A potentially novel aspect is the suggestion to provide specific statutory support for open data rather than rely on public licenses drafted by third parties.
Abelian-Higgs and Vortices from ABJM: towards a string realization of AdS/CMT
Creators: name: Mohammed, Asadig
name: Murugan, Jeff
name: Nastase, Horatiu
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present ansätze that reduce the mass-deformed ABJM model to gauged Abelian scalar theories, using the fuzzy sphere matrices $G^α$. One such reduction gives a Toda system, for which we find a new type of nonabelian vortex. Another gives the standard Abelian-Higgs model, thereby allowing us to embed all the usual (multi-)vortex solutions of the latter into the ABJM model. By turning off the mass deformation at the level of the reduced model, we can also continuously deform to the massive $ϕ^4$ theory in the massless ABJM case. In this way we can embed the Landau-Ginzburg model into the AdS/CFT correspondence as a consistent truncation of ABJM. In this context, the mass deformation parameter $μ$ and a field VEV $$ act as $g$ and $g_c$ respectively, leading to a well-motivated AdS/CMT construction from string theory. To further this particular point, we propose a simple model for the condensed matter field theory that leads to an approximate description for the ABJM abelianization. Finally, we also find some BPS solutions to the mass-deformed ABJM model with a spacetime interpretation as an M2-brane ending on a spherical M5-brane.
description: 43 pages, latex, explanations added in the introduction, end of section 4, and on page 25
Countering Code Injection Attacks With Instruction Set Randomization
Creators: name: Kc, Gaurav S.
name: Keromytis, Angelos D.
name: Prevelakis, Vassilis
Publisher: name: Columbia University
Year: 2003
Subjects: Computer science

description: We describe a new, general approach for safeguarding systems against any type of code-injection attack. We apply Kerckhoff's principle, by creating process-specific randomized instruction sets (e.g., machine instructions) of the system executing potentially vulnerable software. An attacker who does not know the key to the randomization algorithm will inject code that is invalid for that randomized processor, causing a runtime exception. To determine the difficulty of integrating support for the proposed mechanism in the operating system, we modified the Linux kernel, the GNU binutils tools, and the bochs-x86 emulator. Although the performance penalty is significant, our prototype demonstrates the feasibility of the approach, and should be directly usable on a suitable-modified processor (e.g., the Transmeta Crusoe).Our approach is equally applicable against code-injecting attacks in scripting and interpreted languages, e.g., web-based SQL injection. We demonstrate this by modifying the Perl interpreter to permit randomized script execution. The performance penalty in this case is minimal. Where our proposed approach is feasible (i.e., in an emulated environment, in the presence of programmable or specialized hardware, or in interpreted languages), it can serve as a low-overhead protection mechanism, and can easily complement other mechanisms.
Conceptualizing landscapes through language: The role of native language and expertise in the representation of waterbody related terms
Creators: name: Striedl, Philipp
name: Purves, Ross
name: Kong, Inhye
name: Majid, Asifa
Publisher: name: figshare
Year: 2023
Subjects: Other language, communication and culture not elsewhere classified
Sensory processes, perception and performance
Environmental management
Geoinformatics not elsewhere classified

description: Supplementary material to the paper: Conceptualizing landscapes through language: The role of native language and expertise in the representation of waterbody related terms https://doi.org/10.1111/tops.12652
 The data set contains raw data from surveys, the limesurvey code of one of the surveys (in input), analytical code (R markdown), summarised data (in output) and Figures used in the paper (in graphics).
Mapping haptic exploratory procedures to multiple shape representations
Creators: name: Allen, Peter K.
Publisher: name: Columbia University
Year: 1990
Subjects: Robotics

description: Research in human haptics has revealed a number of exploratory procedures (EPs) that are used in determining attributes on an object, particularly shape. This research has been used as a paradigm for building an intelligent robotic system that can perform shape recognition from touch sensing. In particular, a number of mappings between EPs and shape modeling primitives have been found. The choice of shape primitive for each EP is discussed, and results from experiments with a Utah-MIT dextrous hand system are presented. A vision algorithm to complement active touch sensing for the task of autonomous shape recovery is also presented.
Manual tracking in Parkinson's disease : implications for L-dopa-induced dyskinesias
Creators: name: Stevenson, James
Publisher: name: University of British Columbia
Year: 2011

description: Though Parkinson’s disease (PD) is considered to be a prototypical basal ganglia disorder, it has become increasingly clear that this traditional view does not capture the complexity of the disease pathophysiology. For instance, imaging studies demonstrate altered cerebellar activity in PD that may compensate for and/or contribute to the symptoms of the disease. L-dopa-induced dyskinesias (LID) are involuntary writhing movements that commonly occur as a side effect of L-dopa therapy, and despite the prevalence of LID their underlying mechanisms are poorly understood. Altered cerebellar activity in PD may contribute to the pathophysiology of LID, and due to altered ‘forward models’ lead dyskinetic subjects to more heavily rely on ambiguous visual feedback. The principal aim of this thesis was to investigate the ability of PD subjects to de-weight ambiguous visual feedback during motor performance, while examining this ability as well as subtle differences in motor performance across dyskinetic and non-dyskinetic PD subjects. To this end we designed a large-amplitude visually guided tracking task where the target ‘jittered’ about the desired trajectory, and used root mean square (RMS) error and linear dynamical system (LDS) models to quantify tracking performance. The three major findings of this work were: 1) in addition to their known susceptibility to speed, PD subjects off medication were significantly more susceptible to increasing visual uncertainty than control subjects, 2) despite similar RMS error during non-ambiguous tracking the damping ratio parameter of the LDS models was significantly lower for dyskinetic subjects off medication, and 3) dyskinetic PD subjects were significantly more susceptible to visual uncertainty than non-dyskinetic and control subjects, and though L-dopa improved their overall tracking ability, this came at the price of a greater response to and reliance on ambiguous visual feedback. From this work we conclude that PD subjects demonstrate an impaired ability to de-weight ambiguous visual input, possibly due to inadequate forward models, and which may be specific to LID pathophysiology. The presence of motor abnormalities while dyskinetic subjects are off medication and not actively experiencing LID is suggestive of persistent neural plasticity. We argue these findings are related to altered cerebellar function in PD.
Cooperative integration of vision and touch
Creators: name: Allen, Peter K.
Publisher: name: Columbia University
Year: 1990
Subjects: Robotics
Artificial intelligence

description: Vision and touch have proved to be powerful sensing modalities in humans. In order to build robots capable of complex behavior, analogues of human vision and taction need to be created. In addition, strategies for intelligent use of these sensors in tasks such as object recognition need to be developed. Two overriding principles that dictate a good strategy for cooperative use of these sensors are the following: 1) sensors should complement each other in the kind and quality of data they report, and 2) each sensor system be used in the most robust manner possible. We demonstrate this with a contour following algorithm that recovers the shape of surfaces of revolution from sparse tactile sensor data. The absolute location in depth of an object can be found more accurately through touch than vision; but the global properties of where to actively explore with the hand are better found through vision.
Spindown of Isolated Neutron Stars: Gravitational Waves or Magnetic Braking?
Creators: name: Staff, Jan
name: Jaikumar, Prashanth
name: Chan, Vincent
name: Ouyed, Rachid
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the spindown of isolated neutron stars from initially rapid rotation rates, driven by two factors: (i) gravitational wave emission due to r-modes and (ii) magnetic braking. In the context of isolated neutron stars, we present the first study including self-consistently the magnetic damping of r-modes in the spin evolution. We track the spin evolution employing the RNS code, which accounts for the rotating structure of neutron stars for various equations of state. We find that, despite the strong damping due to the magnetic field, r-modes alter the braking rate from pure magnetic braking for B<10^{13}G. For realistic values of the saturation amplitude, the r-mode can also decrease the time to reach the threshold central density for quark deconfinement. Within a phenomenological model, we assess the gravitational waveform that would result from r-mode driven spindown of a magnetized neutron star. To contrast with the persistent signal during the spindown phase, we also present a preliminary estimate of the transient gravitational wave signal from an explosive quark-hadron phase transition, which can be a signal for the deconfinement of quarks inside neutron stars.
description: 25 pages, 9 figs., to be published in The Astrophysical Journal (2012)
On Hawaiian Groups of Some Topological Spaces
Creators: name: Babaee, Ameneh
name: Mashayekhy, Behrooz
name: Mirebrahimi, Hanieh
Publisher: name: arXiv
Year: 2011
Subjects: subject: Algebraic Topology (math.AT)
subject: General Topology (math.GN)
subject: FOS: Mathematics
subject: 55Q05, 55Q20, 54F15, 54D05

description: The paper is devoted to study the structure of Hawaiian groups of some topological spaces. We present some behaviors of Hawaiian groups with respect to product spaces, weak join spaces, cone spaces, covering spaces and locally trivial bundles. In particular, we determine the structure of the $n$-dimensional Hawaiian group of the $m$-dimensional Hawaiian earring space, for all $1\leq m\leq n$.
description: 16 pages. To appear in Topology and its Applications
Coupling life cycle assessment with energy system analysis
Creators: name: Xu, Lei
Publisher: name: Karlsruher Institut für Technologie (KIT)
Year: 2023

description: One of the main drivers for switching the current energy system from a conventional fossil-base to one dominated by renewable technologies is climate change. However, energy system transformation aiming at reducing greenhouse gas (GHG) emissions may lead to increases in other types of environmental impacts. Incorporating environmental impacts beyond climate change into future energy systems is required, in order to develop energy policies that do not, or at least can reduce, conflict with other goals. With this as the background, this thesis couples life cycle assessment (LCA) with energy system analysis, to broaden the scope by including additional environmental impacts, and to switch from a direct emissions perspective to a life cycle perspective. For this purpose, a standard LCA approach is applied to assess energy technologies. Subsequently, the standard LCA is extended to couple with energy system models (ESM) for the assessment of multi-technological energy systems, from both life cycle and energy system perspectives. Considering the methodological challenges that occur due to differences between the models resulting from their different system boundaries, databases, and the levels of detail of their input data, the thesis introduces the Environmental Assessment Framework for Energy System Analysis (EAFESA) as a guideline for studies to cope with model coupling between LCA and ESM. This thesis includes four papers with different study aims. Paper A applies the standard LCA approach for technological assessment. As wind power is one of the most promising renewable energy sources worldwide, a case study assessing the environmental impacts of wind power technologies is conducted. Paper B develops the EAFESA framework and includes a case study to elaborate how to use the framework. Paper C and Paper D are two additional case studies applying the EAFESA framework for model coupling between LCA and ESM, considering, respectively, one of the two model coupling directions. The applications of the EAFESA framework in the case studies confirms the importance and benefits of “integrated thinking” as proposed by EAFESA, which allows minimizing the pitfalls of combining both models comprehensively. At the same time, EAFESA has the potential to raise awareness of issues not often discussed among policymakers. As shown, for example, the decarbonized electricity system will be accompanied by increased metal demand and urban land occupation. Nevertheless, metal demand could be decreased slightly, together with the decrease of GHG emissions, when the system expenditure increases insignificantly.
Measuring mechanical motion with a single spin
Creators: name: Bennett, S. D.
name: Kolkowitz, S.
name: Unterreithmeier, Q. P.
name: Rabl, P.
name: Jayich, A. C. Bleszynski
name: Harris, J. G. E.
name: Lukin, M. D.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study theoretically the measurement of a mechanical oscillator using a single two level system as a detector. In a recent experiment, we used a single electronic spin associated with a nitrogen vacancy center in diamond to probe the thermal motion of a magnetized cantilever at room temperature {Kolkowitz et al., Science 335, 1603 (2012)}. Here, we present a detailed analysis of the sensitivity limits of this technique, as well as the possibility to measure the zero point motion of the oscillator. Further, we discuss the issue of measurement backaction in sequential measurements and find that although backaction heating can occur, it does not prohibit the detection of zero point motion. Throughout the paper we focus on the experimental implementation of a nitrogen vacancy center coupled to a magnetic cantilever; however, our results are applicable to a wide class of spin-oscillator systems. Implications for preparation of nonclassical states of a mechanical oscillator are also discussed.
description: 17 pages, 6 figures
Evaluation Distance Measures Between Gaussian Mixture Models of MFCCs
Creators: name: Jensen, Jesper Hojvang
name: Ellis, Daniel P. W.
name: Christensen, Mads G.
name: Jensen, Soren Holdt
Publisher: name: Columbia University
Year: 2007
Subjects: subject: Electrical engineering
subject: Mathematics
subject: FOS: Mathematics

description: In music similarity and in the related task of genre classification, a distance measure between Gaussian mixture models is frequently needed. We present a comparison of the Kullback-Leibler distance, the earth movers distance and the normalized L2 distance for this application. Although the normalized L2 distance was slightly inferior to the Kullback-Leibler distance with respect to classification performance, it has the advantage of obeying the triangle inequality, which allows for efficient searching.
Sag Harbor Presbyterian Church Interior and Organ, Prior to 1900
Creators: name: Unknown
name: Sag Harbor First Presbyterian Church
Publisher: name: Unknown
Year: 1870
Subjects: Churches
Presbyterian churches
Sag Harbor
Photographs
Organizations
Organ lofts
Organs
Christmas decorations
Gas-lighting

description: A date is estimated based on the use of round style photos, which were popular in the 1870s and 1880s. The gaslights would have also been popular during that time and a little later. This image shows the interior of the church in December, with Christmas decorations. Some of the Minard Lafever architectural details are visible, too.
iLeak: A Lightweight System for Detecting Inadvertent Information Leaks
Creators: name: Kemerlis, Vasileios
name: Pappas, Vasileios
name: Portokalidis, Georgios
name: Keromytis, Angelos D.
Publisher: name: Columbia University
Year: 2010
Subjects: Computer science

description: Data loss incidents, where data of sensitive nature are exposed to the public, have become too frequent and have caused damages of millions of dollars to companies and other organizations. Repeatedly, information leaks occur over the Internet, and half of the time they are accidental, caused by user negligence, misconfiguration of software, or inadequate understanding of an application's functionality. This paper presents iLeak, a lightweight, modular system for detecting inadvertent information leaks. Unlike previous solutions, iLeak builds on components already present in modern computers. In particular, we employ system tracing facilities and data indexing services, and combine them in a novel way to detect data leaks. Our design consists of three components: uaudits are responsible for capturing the information that exits the system, while Inspectors use the indexing service to identify if the transmitted data belong to files that contain potentially sensitive information. The Trail Gateway handles the communication and synchronization of uaudits and Inspectors. We implemented iLeak on Mac OS X using DTrace and the Spotlight indexing service. Finally, we show that iLeak is indeed lightweight, since it only incurs 4% overhead on protected applications.
Computing the Ramsey Number $R(K_5-P_3,K_5)$
Creators: name: Calvert, Jesse A.
name: Schuster, Michael J.
name: Radziszowski, Stanisław P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Combinatorics (math.CO)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 05C55

description: We give a computer-assisted proof of the fact that $R(K_5-P_3, K_5)=25$. This solves one of the three remaining open cases in Hendry's table, which listed the Ramsey numbers for pairs of graphs on 5 vertices. We find that there exist no $(K_5-P_3,K_5)$-good graphs containing a $K_4$ on 23 or 24 vertices, where a graph $F$ is $(G,H)$-good if $F$ does not contain $G$ and the complement of $F$ does not contain $H$. The unique $(K_5-P_3,K_5)$-good graph containing a $K_4$ on 22 vertices is presented.
Lattice thermal conductivity of graphene with conventionally isotopic defects
Creators: name: Adamyan, Vadym
name: Zavalniuk, Vladimir
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The thermal conductivity of doped graphene flake of finite size is investigated with emphasis on the influence of mass of substituting atoms on this property. It is shown that the graphene doping by small concentrations of relatively heavy atoms results in a disproportionately impressive drop of lattice thermal conductivity.
description: 12 pages, 3 figures
D2.5: Update on PRACE's strategic and operational developments towards EuroHPC JU
Creators: name: Veronica Teodor
name: Oriol Pineda
Publisher: name: Zenodo
Year: 2022
Subjects: Deliverable
HPC
Research infrastructure

description: This deliverable reports on the main activities of Work Package 2 (WP2) during the last 12 months of the PRACE-6IP project (January 2022-December 2022). These include the following:

Support to PRACE 2 programme, including a view towards PRACE 3;
Provision of input to PRACE's position in the EuroHPC era and the impact for the HPC community of the PRACE services, activities and their interruption once the PRACE-
6IP will come to an end;
Peer Review activity undertaken for the last PRACE 2 Calls and first EuroHPC JU Calls;
Update of the stakeholder management;
Legal support to the PRACE Infrastructure and other work packages of the project
Impact assessment.
The reporting on the PRACE 2 status within the PRACE Implementation Phase projects was initiated during PRACE-4IP (D2.2 "Second Report on PRACE 2.0 Development"). This report was continued during PRACE-5IP (D2.1 "Report on PRACE 2, TNA, DECI and KPIs Year 1" and D2.3 "Report on PRACE 2, TNA and DECI Year 2") and PRACE-6IP (D2.1 "PRACE role in the European HPC strategy and implementation", D2.4 "Report on PRACE strategic and operational developments towards EuroHPC-JU"). The current deliverable provides an update on this activity during the last year of the PRACE-6IP project (Jan 2022-Dec 2022). It reports on the last calls in the Second Period of operations of the PRACE pan-European Research Infrastructure, called PRACE 2, which began in 2017 and succeeded the PRACE agreement for the Initial Period (referred to as PRACE 1). This is complemented with a number of indicators to show the impact of PRACE as a pan-European research infrastructure, including statistics on gender and country participation for the last PRACE 2 calls. As part of the PRACE 2 programme, it presents also a summary of the final reports of the High Level Support Teams. 
Another important activity during the last 12 months was the Peer Review activity where the PRACE Peer Review office managed not only the last PRACE 2 calls, but also the first EuroHPC JU calls and the transfer of the Peer Review activities from PRACE to EuroHPC JU, and its implementation. The deliverable includes also a list of indicators that EuroHPC JU could monitor and use to develop a set of HPC access KPIs.
With the last allocations of PRACE 2 ending in March 2023, this deliverable underlines the added value of the PRACE services and activities, and their impact for the HPC community once the PRACE Implementation Phase projects will come to an end in December 2022. In this regard, further considerations regarding PRACE's role and the future PRACE 3 in relation to the EuroHPC JU are presented.
Additionally, this document presents an analysis of the European HPC landscape including latest coordination events organised by PRACE-6IP and feedback of the main important stakeholders with regards to the future of this ecosystem.
Heart rate response and chronotropic incompetence during cardiopulmonary exercise testing in childhood acute lymphoblastic leukemia survivors
Creators: name: Bertrand, Émilie
name: Caru, Maxime
name: Lemay, Valérie
name: Andelfinger, Gregor
name: Laverdiere, Caroline
name: Krajinovic, Maja
name: Sinnett, Daniel
name: Curnier, Daniel
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Cardiopulmonary exercise tests (CPET) focusing on analyses of heart rate (HR) responses and chronotropic incompetence (CI) could provide early information about treatment’s negative cardiac effects. We examined childhood acute lymphoblastic leukemia (ALL) survivors’ HR response during maximal CPET and identified survivors with CI. A total of 250 childhood ALL survivors underwent a CPET on ergocycle to assess their HR response. We used a multiparametric structure of three methods to assess survivors’ CI, as follows: 1) age-predicted HRmax (APMHR): failure to achieve 85% of the APMHR at the peak of CPET; 2) HR reserve (HRR): failure to achieve 80% of the HRR at the peak of CPET; and 3) metabolic chronotropic relationship (MCR): failure to reach an MCR slope ratio >0.8 at each stage of the CPET. Among 250 childhood ALL survivors, 216 survivors performed a maximum CPET. We observed that 73 males and 74 females did not achieve their predicted HRmax. We found that 6 survivors did not achieve 85% of their APMHR (80.9 ± 3.9%) and had an MCR below 80% (53.9 ± 13.8%). In addition, 16 survivors did not achieve 80% of their HRR (71.0 ± 7.4%) and among them, 15 survivors had an MCR below 80% (61.0 ± 12.1%). Survivors with CI had a significantly lower cardiorespiratory fitness than those without CI. This study shows that survivors are at risk of developing altered HR responses and CI many years after the end of their cancer treatments. These findings highlight the importance of early detection of cardiac damage due to cancer treatments.
The Policeman, the President, the Professor, an Apology, and a Round of Beers
Creators: name: Mitchell, Lincoln A.
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Political science
subject: FOS: Political science

description: If Obama, Gates and Crowley ever get together for that beer, it will be a good photo and probably an interesting discussion, but it will not change how African Americans are treated by police.
Delayed diagnosis of Griscelli syndrome type 2 with compound heterozygote RAB27A variants presenting with pulmonary failure
Creators: name: Messinger, Yoav H.
name: Pozos, Tamara C.
name: Griffiths, Anne G.
name: Mize, William A.
name: Olson, Damon R.
name: Smith, Angela R.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Delayed diagnosis of Griscelli syndrome type 2 with compound heterozygote RAB27A variants presenting with pulmonary failure
D8.5: Final Report: including performance results on (pre)Exascale systems
Creators: name: Alex Upton
name: Joost VandeVondele
name: Fabio Affinito
Publisher: name: Zenodo
Year: 2022
Subjects: Deliverable
HPC
Research infrastructure

description: From April 2019 to June 2022, Work Package 8 of PRACE-6IP oversaw a number of projects developing forward-looking software solutions. These projects were selected following two competitive calls for proposals; eight started in April 2019 following the first call for proposals, and two additional projects started in January 2020 following the second call for proposals. Eight of the projects were active, albeit with a reduced level of activity, during the WP8 extension period, which ran from November 2021 to June 2022. This deliverable builds upon the previous deliverable D8.3, that provided an overview of the first phase of the project, and deliverable D8.4, that provided an overview of the second phase of the project. A comprehensive overview is provided of the progress of the projects during WP8, including a summary of the compatibility of the WP8 projects on the leading European HPC systems, as well as individual sections about each of the projects with 1) a summary of each projects and the goals 2) benchmarking results on leading HPC systems 3) engagement with stakeholders and outreach activities and 4) an overall assessment of achievements and areas for future developments. A separate annex is included that provides an overview of the performance and benchmarking results obtained by the eight projects that were active during the WP8 extension period. Overall, it is fair to say that the projects have carried out a thorough level of work, and have contributed to the success of Work Package 8 of PRACE-6IP.
Acquisition and interpretation of 3-D sensor data from touch
Creators: name: Allen, Peter K.
name: Michelman, Paul
Publisher: name: Columbia University
Year: 1990
Subjects: Robotics

description: A description is given of the use of touch sensing as part of a larger system the authors are building for 3-D shape recovery and object recognition using touch and vision methods. The authors focus on three exploratory procedures (EPs) they have built to acquire and interpret sparse 3D touch data: grasping by containment, planar surface exploration, and surface contour exploration. Experimental results for each of these procedures are presented. The EPs can be used in a coarse-to-fine sensing strategy that tries to build shape descriptions at a number of levels. An important feature of this system is the multiple representations used in recovering and reasoning about shape.
The endocannabinoid system and female sexual arousal
Creators: name: Klein, Carolin
Publisher: name: University of British Columbia
Year: 2011

description: Evidence from several lines of research points to the potential role of the endocannabinoid system in female sexual functioning. This evidence includes results from studies describing the subjective effects of exogenous cannabinoids on sexual functioning in humans and the observable effects of exogenous cannabinoids on sexual functioning in other species, as well as the results from studies investigating the location of cannabinoid receptors in the brain and periphery, and the effects of cannabinoid receptor activation on neurotransmitters implicated in sexual functioning. However, while these lines of research are suggestive of a role of the endocannabinoid system in female sexual functioning, no studies investigating the relationship between levels of endogenous cannabinoids (i.e., arachidonoylethanolamide [anandamide or AEA] and 2-arachidonoylglycerol [2-AG]) and sexual functioning, or investigating the effects of exogenous cannabinoid use on physiological measures of sexual functioning in humans, have been conducted. Experiments 1 and 2 of the present dissertation are the first known studies to measure and examine circulating endocannabinoid levels in relation to both subjective and physiological indices of sexual arousal in women. Experiment 3 is the first known study to examine the relationship between exogenous cannabinoid use and physiological sexual arousal in women. Physiological sexual arousal in all three studies was measured via the vaginal photoplethysmograph. Although the results of Experiment 1 did not reveal an association between endocannabinoid levels and female sexual arousal, the results of Experiment 2 revealed a significant relationship, whereby increases in both physiological and subjective indices of sexual arousal were significantly associated with decreases in endocannabinoid (AEA and/or 2-AG) levels. Experiment 3 revealed that women who use marijuana show significantly smaller increases in physiological sexual arousal in response to erotic film stimuli than women who do not use marijuana. The findings from these studies support the hypothesis that the endocannabinoid system plays a role in female sexual functioning. This line of research has broad clinical and research implications, not only in terms of furthering understanding of the biological mechanisms underlying female sexual functioning, but also in terms of finding effective treatments for sexual dysfunctions in women.