cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Titanium dioxide nanoparticles: synthesis, characterisations and aquatic ecotoxicity effects
Creators: name: Mezni, Amine
name: Alghool, Samir
name: Sellami, Badreddine
name: Saber, Nesrine Ben
name: Altalhi, Tariq
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences

description: Little information is available on the potential ecotoxicity of nanomaterials in the marine environment. In particular, the aquatic ecotoxicity impact of titanium dioxide (TiO2) has been rarely reported. To carefully address this issue, we report on the synthesis of TiO2 NPs using solvothermal process. The structure and morphology of the prepared TiO2 nanoparticles were characterised using different techniques. To study the potential ecotoxicity effect of TiO2, antioxidant system of mediterranean bivalves (Mytilus galloprovincialis) was used, measuring three oxidative biomarkers (ROS production, SOD activity and GSH/GSSG level). No considerable effect was found in the digestive glands of any of the groups treated with TiO2 with concentration gradients ranging from 1 to 100 mg/L. Thus, the level of the superoxide anion, the activity of an antioxidant enzyme superoxide dismutase (SOD) and the GSH/GSSG ratio showed no significantly differences in digestive glands of all treated groups compared to the control. However, slight modifications were observed in the gills at high concentrations. These results demonstrated that TiO2 appears to exert little toxicity on marine mussels after a short-term exposure at high concentration. However, before considering the use of this nanomaterial in various applications, further complementary studies are required in order to ensure the environmental safety of these NPs.
Boletín Derecho y Vida - Ius et Vita - Edición 115
Creators: name: Santamaría Echeverría, Orlando Enrique
name: Muñoz, José M.
name: Marinaro, José Ángel
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Innovaciones tecnológicas
subject: Gestión de información
subject: Ensayos clínicos
subject: Ciencia cognoscitiva
subject: Teoría de las máquinas
subject: Visión por computador
subject: Ensayos clínicos in silico
subject: Gestión de datos
subject: Desafíos regulatorios
subject: Innovación tecnológica
subject: Consideraciones éticas
subject: Inteligencia artificial (IA)
subject: Teoría computacional
subject: Habitación china
subject: Cognición 4E
subject: Singularidad tecnológica
subject: Tecnoanimismo
subject: Entidad interactiva artificial (EIA).

description: Este artículo analiza las oportunidades y retos jurídicos de los ensayos clínicos in silico (ISCT). Los ISCT utilizan simulaciones computacionales basadas en datos para innovar en el desarrollo y evaluación de medicamentos y dispositivos médicos. A pesar de su potencial para reducir costos y mejorar la eficiencia, plantean desafíos significativos en cuanto a la gestión de datos, ética, privacidad, obsolescencia tecnológica, y regulación. El crecimiento del mercado de ISCT evidencia su importancia, pero también subraya la necesidad de un marco regulatorio claro y prácticas responsables para su implementación ética. ¿Es la inteligencia artificial (IA) una verdadera inteligencia? La forma en que concibamos el estatus ontológico de la IA influirá decisivamente en nuestra perspectiva ética y social sobre este tipo de entidad, y esto a su vez determinará el estatus legal que sea conveniente otorgarle. La visión mainstream según la cual la IA es, o pronto será, equiparable en su inteligencia a la que poseemos los seres humanos parte de una base conceptual que acepta la teoría computacional, según la cual la consciencia consiste en el manejo simbólico de información entrante y la producción de unos resultados como fruto de dicho manejo. Esta forma de entender la consciencia lleva, en último término, no solo a la antropomorfización de la IA, sino incluso al tecnoanimismo (es decir, la atribución de características cuasi-sobrenaturales a la IA), lo cual implica una subordinación ontológica del humano a la máquina. Sin embargo, la IA no es capaz de pensar; solo puede aparentar que piensa. Es por ello que, en este artículo, sugerimos el nombre de entidad interactiva artificial (EIA) como alternativa semántica que sirva de base para una concepción humanista de la relación humano–máquina en los planos ontológico-antropológico y ético-legal.
title: Segregation and properties at curved vs straight (0001) inversion boundaries in piezotronic ZnO bicrystals
Creators: name: Trapp, Maximilian
name: Keil, Peter
name: Frömling, Till
name: Rödel, Jürgen
name: Kleebe, Hans‐Joachim
Publisher: name: American Ceramic Society
Year: 2022

description: TEM and SEM investigations of ZnO bicrystal interfaces were undertaken with an aim to study the correlation of local grain-boundary structure, segregation, and elec-trical transport perpendicular to the interface. To this end, varistor-like ZnO bicrystals with piezotronic characteristics were chosen with (0001)║(0001) tail-to-tail orienta-tion with respect to the c-axis. In order to contrast different local grain-boundary structures with different coherency and segregation of bismuth, but identical macro-scopic polarization state, two complementary processing techniques were applied. A diffusion-bonded bicrystal with an intermediate thin film containing Zn–Bi–Co–O provided a straight interface as reference. In contrast, a ZnO bicrystal prepared by epitaxial solid-state transformation was manufactured by bonding two ZnO single crystals with a 100 μm thick polycrystalline ZnO varistor material with a typical dopant composition including bismuth and cobalt. This structure was annealed to the point that a bicrystal was formed with the varistor concentration at the boundary, which was strongly curved due to the polycrystalline microstructure still providing a shadow image at the interface. The results highlight a distinct correlation between local interfacial morphology, degree of segregation of bismuth, and degree of non-linearity of the electrical transport across the interface.
Supplementary document for Multiband tunable exciton-induced transparencies: Exploiting both strong and intermediate coupling in a nanocube-hexagonal-nanoplate heterodimer J-aggregates hybrid - 6117399.pdf
Creators: name: Hu, Zhiwei
name: Cui, Ximin
name: Li, Yang
name: Han, Xiaobo
name: hu, huatian
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supporting data
(Supplementary Material B) _ Preliminary analysis workflows, selected results, and Wsa vs. Wdr-b analysis
Creators: name: Clendenon, Cedric
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310913
subject: Invertebrate biology
classificationCode: 310901
subject: Animal behaviour

description: This is a Word document containing two parts. Part one shows supplementary figures for the preliminary analysis of scorpion, tarantula, and crayfish experimental trackway data using Orange Data Mining software, specifically regarding workflows and selected results. Part two shows supplementary figures providing evidence for the merging of the wetter than usual wet drying (Wdr) trackways with the wet saturated (Wsa) condition.
A multicomponent diffusion model for an all-quinone redox flow battery membrane
Creators: name: Gaël, Mourouga
name: Sansone Caterina
name: Iojoiu Cristina
name: Schumacher Jürgen
Publisher: name: Zenodo
Year: 2019
Subjects: Flow batteries
Membrane
Transport
Crossover
Capacity fade
Lifetime predictions
aqueous organic
osmosis
multicomponent diffusion
Stefan-Maxwell

description: We aim to provide a reliable tool for the prediction of:
 • impact of membrane characteristics, i.e. thickness, conductivity, water content on
 current density
 • Impact of crossover of different species on capacity fade based solely on existing experiments that are already performed during membrane characterization.
title: La méthode Total Physical Response, comme stratégie d’enseignement-apprentissage d’une langue seconde au Secondaire I
title: La méthode Total Physical Response, comme stratégie d’enseignement-apprentissage d’une langue seconde au Secondaire I
titleType: AlternativeTitle
Creators: name: Quittet, Léa
name: Zenger, Orane
Publisher: name: Unknown
Year: 0

description: En tant que futures enseignantes de l’anglais au Secondaire I, nous nous sommes intéressées aux différentes stratégies d’enseignement et d’apprentissage qui fonctionnent en termes d’efficacité de mémorisation pour la réussite de nos élèves. L’approche TPR - Total Physical Response - est une méthode d’enseignement langagière basée sur la coordination du langage et du mouvement. Cette approche est pertinente parce qu’elle induit une attitude positive de la part des élèves, et s’avère très efficace quant à la rapidité de mémorisation qu’elle engendre. Ludique et motivante, cette méthode a déjà fait ses preuves depuis de nombreuses années au niveau théorique et pratique à l’école primaire. Nous nous sommes alors interrogées sur la possibilité et la pertinence d’utiliser cette méthode, qui joint le geste à la parole pour faciliter la mémorisation, sur un public plus âgé, des adolescents1 du Secondaire I. Dans cette étude, vous trouverez la façon dont nous avons mis en place une séquence d’enseignement axée sur la méthode TPR dans une classe de 11VG de niveau 1, son analyse réflexive, ainsi que les avantages et contraintes de cette méthode avec des adolescents. La méthode TPR est applicable au Secondaire I, même si les élèves ne sont pas prêts à la réutiliser à des fins d’apprentissage de manière autonome.
Referenciais teóricos sobre a temática “gestão de bibliotecas”: uma investigação na literatura em face da base de periódicos em ciência da informação (BRAPCI)
Creators: name: Anna, Jorge Santa
Publisher: name: figshare
Year: 2018
Subjects: subject: 80706 Librarianship
subject: FOS: Media and communications
subject: Library and Information Studies

description: As unidades e os serviços de informação situam-se em um contexto de intensa redefinição. Os reflexos provocados com a adesão às novas tecnologias permitem um fluxo contínuo de alterações em que, ao passo que surgem novos produtos e serviços, provoca-se obsolescência de outros. As tecnologias contemporâneas têm o potencial, em grande parte, de realizar os procedimentos técnicos anteriormente realizados por humanos. Contudo, enquanto os fazeres técnicos são substituídos por máquinas, outros problemas surgem, o que requer a intervenção humana, no sentido de gerenciar atividades e processos de trabalho, tecnologias e relações humanas. Assim, este artigo analisa o que vem sendo publicado a respeito do assunto “Gestão de Bibliotecas”, por decorrência, analisando o papel do bibliotecário gestor. Reflete acerca dos processos de trabalho que orientam as atividades em uma biblioteca. Descreve o papel do bibliotecário ao deixar o perfil técnico para habilitar-se como gestor. Realiza levantamento bibliográfico na Base de Periódicos em Ciência da Informação, através dos descritores “Gestão de Bibliotecas” e “Gestão de Unidade de Informação”. Conclui-se que, embora a produção científica a respeito dessa temática tem aparecido na literatura, a maioria dos trabalhos analisados ainda está focada nos procedimentos técnico-operacionais. Constatou-se que os estudos analisados abordam com maior intensidade a gestão das atividades e processos de trabalho e gestão com foco nas tecnologias utilizadas na unidade, sendo bastante escassas as discussões acerca da gestão do fator humano nos ambientes e serviços de informação.
rotation angle of the deflection stem
Creators: name: Li, Jinjin
Publisher: name: figshare
Year: 2022
Subjects: subject: 90509 Water Resources Engineering
subject: FOS: Civil engineering

description: The experimental data are collected from Dunn et al. (1996) and Kubrak et al. (2008).The experimental data of Dunn et al. (1996) is shown in The rotation angle of the deflection stem of Dunn et al. (1996) is shown in table S3, which is calculated from the average curvature.The rotation angle of the deflection stem of Kubrak et al. (2008) is shown in table S4.
MOESM5 of Genome-wide RNAi screen in Drosophila reveals Enok as a novel trithorax group regulator
Creators: name: Umer, Zain
name: Akhtar, Jawad
name: Khan, Muhammad
name: Shaheen, Najma
name: Haseeb, Muhammad
name: Mazhar, Khalida
name: Mithani, Aziz
name: Anwar, Saima
name: Tariq, Muhammad
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 5: Table S2. List of primers used in this study.
title: Quadrupole moments of odd-A ⁵³⁻⁶³Mn: Onset of collectivity towards N = 40
Creators: name: Babcock, Carla
name: Heylen, Hanne
name: Bissell, Mark L.
name: Blaum, Klaus
name: Campbell, Paul
name: Cheal, Bradley
name: Fedorov, D.V.
name: Garcia Ruiz, Ronald Fernando
name: Geithner, Wolfgang
name: Gins, Wouter
name: Day Goodacre, Thomas
name: Grob, L.K.
name: Kowalska, Magdalena A.
name: Lenzi, Silvia Monica
name: Maass, Bernhard
name: Malbrunot-Ettenauer, S.
name: Marsh, Bruce Allan
name: Neugart, Rainer
name: Neyens, Gerda
name: Nörtershäuser, Wilfried
name: Otsuka, Takaharu
name: Rossel, Ralf Erik
name: Rothe, Sebastian
name: Sánchez, Rodolfo M.
name: Tsunoda, Yusuke
name: Wraith, Calvin
name: Xie, Liang
name: Yang, Xiaofei
Publisher: name: Elsevier
Year: 2022

description: The spectroscopic quadrupole moments of the odd–even Mn isotopes between N=28 and N=38 have been measured using bunched-beam collinear laser spectroscopy at ISOLDE, CERN. In order to increase sensitivity to the quadrupole interaction, the measurements have been done using a transition in the ion rather than in the atom, with the additional advantage of better spectroscopic efficiency. Since the chosen transition is from a metastable state, optical pumping in ISOLDE’s cooler and buncher (ISCOOL) was used to populate this state. The extracted quadrupole moments are compared to large-scale shell model predictions using three effective interactions, GXPF1A, LNPS and modified A3DA. The inclusion of both the 1νg9/2and 2νd5/2orbitals in the model space is shown to be necessary to reproduce the observed increase in the quadrupole deformation from N=36 onwards. Specifically, the inclusion of the 2νd5/2orbital induces an increase in neutron and proton excitations across the reduced gaps at N=40and Z=28, leading to an increase in deformation above N=36.
title: L'utilisation d'images issues de la culture populaire de masse déclenche-t-elle la motivation des élèves dans la pratique des arts visuels ?
title: L'utilisation d'images issues de la culture populaire de masse déclenche-t-elle la motivation des élèves dans la pratique des arts visuels ?
titleType: AlternativeTitle
Creators: name: Cavadas, Kelly
name: Sudan, Aurèle
Publisher: name: Unknown
Year: 0
Subjects: subject: arts visuels
subject: motivation
subject: musée de classe
subject: la valise musée
subject: références
subject: culture populaire

description: Ce travail propose d’analyser la création de notre outil de travail, à savoir des amorces comportant des références culturelles populaires, et d’analyser si cet outil a permis d'enclencher une motivation chez les élèves. Évoluant dans une société concentrée sur le divertissement par l’image et se construisant autour d’une boulimie audiovisuelle, nous avons voulu questionner celle-ci et l’intégrer dans nos programmes d’enseignement. Le rapport de l’image face à la motivation des élèves nous a rapidement questionnés et nous avons donc décidé de mener à bien une expérience confrontant ces images “mainstream” pour y inclure des consignes d’arts visuels. L’image culturelle populaire peut-elle motiver les élèves à pratiquer les arts visuels ? Est-il possible de proposer des exercices en lien avec la culture visuelle de nos élèves ? C’est en voulant nous rapprocher de leur univers que nous avons construit seize amorces de travail intégrant les références visuelles actuelles et en les mêlant à l’histoire de l’art. Ces amorces nous permettent de confirmer nos hypothèses quant à la motivation des élèves, mais aussi de pouvoir ouvrir nos champs de réflexion pour nos futures séquences d’arts visuels. Les résultats obtenus auprès des élèves, après la mise en œuvre de notre projet, nous ont montré des signes allant dans le sens de nos hypothèses, avec cette classe en tout cas. Nous supposons que l’utilisation de références populaires auprès des élèves permet de générer une motivation supplémentaire dans l’approche du travail des arts visuels. Il semblerait également que cela permette à certain·e·s élèves de s’exprimer plus facilement au sujet de leur processus créatif, ainsi que de leur rapport au monde artistique de manière plus générale.
(Supplementary Material C) _ Complex Trackway Data Tables for Trend Visualizations
Creators: name: Clendenon, Cedric
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310913
subject: Invertebrate biology
classificationCode: 310901
subject: Animal behaviour

description: This is a spreadsheet of tables containing univariate descriptive statistics (e.g. max, min, and median) for each variable split by condition and invertebrate species (scorpion, tarantula, and crayfish). The “arsenal” package in R Studio was used (1) for binary variables, to gather the percentages of absent, present, and missing trackway characteristics, and (2) for ratio variables, to gather the number of ATS with positive values, the number of ATS with missing values, and the maximum, median, and minimum values (Heinzen et al., 2021; R Core Team, 2020). These values were copied to this Excel spreadsheet, and then the values for each ratio (not binary) variable were divided by the maximum value across all five conditions, multiplied by 100, and rounded to the nearest integer.
Supplementary Material for: Prognostic Value of miR-375 for Survival Outcomes in Various Cancers: A Systematic Review and Meta-Analysis
Creators: name: Dan, B.
name: Luo, J.
name: Li, K.
name: Chen, S.
Publisher: name: Karger Publishers
Year: 2018
Subjects: Medicine

description: Background: miR-375 plays a role in tumor progression; however, its potential as a prognostic factor in cancer remains unclear. This meta-analysis assessed the value of miR-375 as a global prognostic biomarker in human cancer. Methods: A systematic literature review was performed to retrieve publications with relevant survival data. Pooled hazard ratios (HRs) were calculated for low miR-375 expression. Publication bias was examined. Results: Data were extracted from 11 studies of 1,797 patients (low expression in 769 cases; high in 1,028 cases). The pooled HR for overall/cumulative survival (OS/CS) was 1.90 (95% confidence interval (CI) 1.57–2.29) and the pooled HR for disease-free, recurrence-free or progression-free survival (DFS/RFS/PFS) was 1.93 (95% CI 1.39–2.67), indicating low miR-375 expression was associated with significantly poorer outcomes compared to normal/high miR-375 expression. Subgroup analysis revealed miR-375 might be a good prognostic factor in cancer, regardless of population, sample type, and cancer type. The prognostic value of miR-375 in non-Chinese patients was particularly high (pooled HR > 2). Conclusion: Low miR-375 expression could represent a valuable prognostic marker in various cancers. Circulating miR-375 Levels may provide a useful non-invasive, practical prognostic biomarker. However, the prognostic value of miR-375 in specific cancer types remains unclear; further studies are warranted.
title: Evolution of nuclear structure in neutron-rich odd-Zn isotopes and isomers
Creators: name: Wraith, Calvin
name: Yang, Xiaofei
name: Xie, Liang
name: Babcock, Carla
name: Bieron, Jacek
name: Billowes, Jonathan
name: Bissell, Mark L.
name: Blaum, Klaus
name: Cheal, Bradley
name: Filippin, Livio
name: Garcia Ruiz, Ronald Fernando
name: Gins, Wouter
name: Grob, L.K.
name: Gaigalas, Gediminas
name: Godefroid, Michel
name: Gorges, Christian
name: Heylen, Hanne
name: Honma, Michio
name: Jo̊nsson, Per
name: Kaufmann, Simon
name: Kowalska, Magdalena A.
name: Krämer, Jörg
name: Malbrunot-Ettenauer, S.
name: Neugart, Rainer
name: Neyens, Gerda
name: Nörtershäuser, Wilfried
name: Nowacki, Frédéric
name: Otsuka, Takaharu
name: Papuga, Jasna
name: Sánchez, Rodolfo M.
name: Tsunoda, Yusuke
name: Yordanov, Deyan Todorov
Publisher: name: Elsevier
Year: 2022

description: Collinear laser spectroscopy was performed on Zn (Z=30) isotopes at ISOLDE, CERN. The study of hyperfine spectra of nuclei across the Zn isotopic chain, N=33–49, allowed the measurement of nuclear spins for the ground and isomeric states in odd-Aneutron-rich nuclei up to N=50. Exactly one long-lived (>10 ms) isomeric state has been established in each 69–79Zn isotope. The nuclear magnetic dipole moments and spectroscopic quadrupole moments are well reproduced by large-scale shell–model calculations in the f5pg9and fpg9d5model spaces, thus establishing the dominant term in their wave function. The magnetic moment of the intruder Iπ=1/2+isomer in 79Zn is reproduced only if the νs1/2orbital is added to the valence space, as realized in the recently developed PFSDG-U interaction. The spin and moments of the low-lying isomeric state in 73Zn suggest a strong onset of deformation at N=43, while the progression towards 79Zn points to the stability of the Z=28 and N=50 shell gaps, supporting the magicity of 78Ni.
НОРМАТИВНО-ПРАВОВОЕ РЕГУЛИРОВАНИЕ СФЕРЫ ОБРАЗОВАНИЯ НА МЕЖДУНАРОДНОМ УРОВНЕ
Creators: name: А. А. Чапенко
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2019
Subjects: образование
ООН
правовое регулирование
права человека
регулирование образования.

description: Статья посвящена анализу нормативно-правовых документов, регулирующих сферу образования на международном уровне. Рассматриваются различные уровни правового регулирования, где ключевое место отводится ООН и ее структурам. Как показал анализ, большинство документов посвящено правам разных людей на образования, вне зависимости от расы, возраста, физического здоровья.
title: Comment favoriser le passage d’un intérêt en situation à un intérêt individuel en parkour ?
title: Comment favoriser le passage d’un intérêt en situation à un intérêt individuel en parkour ?
titleType: AlternativeTitle
Creators: name: Monachon, Nicolas
name: Seiler, Floriane
Publisher: name: Unknown
Year: 0
Subjects: subject: intérêt en situation
subject: intérêt individuel
subject: éducation physique
subject: parkour
subject: valeurs

description: Nous estimons qu’il est plus que jamais nécessaire d’inculquer aux jeunes l’envie de pratiquer le sport en dehors de l’institution scolaire, et l’approche que nous avons choisie se base sur la théorie de l’intérêt. Nous avons basé notre étude sur le modèle de l’intérêt d’Hidi et Renninger, car, depuis sa publication en 2006, ce dernier est devenu une référence. Ce travail a pour question de recherche : « comment favoriser le passage de l’intérêt en situation vers l’intérêt individuel en parkour ? ». Afin d’y apporter une réponse, nous avons centré notre étude sur le troisième facteur de l’intérêt individuel : « valeurs relatives à l’importance de l’activité et intention de développer ses connaissances ». Pour agir sur ce dernier, nous avons décidé de développer une séquence de quatre leçons permettant aux élèves de s’autoréguler au maximum. Nous avons distribué trois questionnaires sur l’intérêt en situation à 12 items lors des deuxièmes et quatrièmes leçons, ainsi que dans une activité contrôle, puis un questionnaire sur l’intérêt individuel à 14 items à la fin de la quatrième leçon. Les résultats des analyses de régressions montrent que le maintien d’un intérêt en situation basé sur les valeurs prédit positivement les connaissances sur l’importance du parkour et l’intention de développer ses connaissances (β = .52) expliquant 54% de sa variance totale. Ceci prouve que l’intérêt en situation basé sur les valeurs est un facteur essentiel pour passer d’un intérêt en situation à un intérêt individuel en parkour.
ПРОТИВОДЕЙСТВИЕ ДЕЯТЕЛЬНОСТИ ДЕСТРУКТИВНЫХ ОРГАНИЗАЦИЙ КРИМИНАЛЬНОЙ НАПРАВЛЕННОСТИ (СЕКТ), ПОСЯГАЮЩИХ НА ЛИЧНОСТЬ И ПРАВА ГРАЖДАН
Creators: name: А. Е. Шалагин
name: А. Д. Идиятуллов
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2019
Subjects: преступление
преступность
секты
деструктивные организации криминальной направленности
самоубийство
предупреждение
профилактика
противодействие.

description: В статье рассмотрены криминологические аспекты преступлений, связанных с созданием и участием в некоммерческой организации, посягающей на личность и права граждан. Дается определение, рассматриваются характерные признаки таких организаций, приводится их классификация. Анализируются причины возникновения и функционирования деструктивных организаций (сект), показана их криминальная активность и взаимосвязь с феноменом самоубийства. Значительное внимание уделено личности организатора, активным участникам, адептам таких групп и сообществ. Выделены меры профилактического и корректирующего воздействия.
КУЛЬТУРНО-ВОСПИТАТЕЛЬНАЯ ФУНКЦИЯ РОССИЙСКОГО ГОСУРДАСТВА И ПРИНЦИПЫ АДМИНИСТРАТИВНО-ПРАВОВОГО РЕГУЛИРОВАНИЯ КУЛЬТУРЫ
Creators: name: К. А. Южанинова
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2019
Subjects: функции государства
принципы правового регулирования
культура
культурно-воспитательная функция
правовое государство.

description: В настоящей статье автором анализируются актуальные для науки административного права вопросы функций государственного управления и принципов правового регулирования культурной сферы в Российской Федерации. По результатам исследования различных позиций современных правоведов сформировано актуальное определение функции государства, культурно-воспитательной функции России, выделены основные специальные (административно-правовые) принципы правового регулирования культурного сектора: принцип специальных форм защиты, принцип сочетания форм собственности, принцип дифференциации уровня управления в зависимости от объекта.
Virtual high-throughput screening: potential inhibitors for the mycobacterial α-subunit of tryptophan synthase
Creators: name: Mohan, Surender
name: Jade, Dhananjay
name: Gupta, Sonal
name: Ayyamperumal, Selvaraj
name: Chandrasekar, M. J. N
name: Nanjan, M. J.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Mycobacterium tuberculosis (Mtb), which causes tuberculosis (TB), is the world’s most successful pathogen. If it is to survive in phagosomes, the tryptophan biosynthetic pathway is essential. The α-subunit of tryptophan synthase (TRPS) executes the irreversible catalysis of indole-3-glyceral-3-phosphate to generate indole. The β-subunit catalyses the conversion of indole and serine to tryptophan. Targeting the TRPS α-subunit may, therefore, render the enzyme inactive. The crystal structure of α-subunit downloaded from the protein data bank (PDB: 5OCW) has gaps at the amino acid sequence positions in three places. We, therefore, retrieved the entire amino acid sequence of the protein from the UniProt and built a complete protein structure by adding the missing amino acids using a Modeller. The 3D model of the α-subunit was then used as the target to develop inhibitors for Mtb. We downloaded 58,699 natural products from the Maybridge database. After space filtering, molecular docking, molecular dynamic simulation and binding free energy calculation were done to develop inhibitors for the TRPS α-subunit. Out of the 18 compounds selected, five virtual hit compounds, namely MFCD00103482, MFCD00118123, MFCD04110719, MFCD01005315 and MFCD04112426, bind well to the TRPS α-subunit. These five potential inhibitors for Mtb will be taken for preclinical testing.
ОБЩИЕ ПРИНЦИПЫ ПРАВОВОГО РЕГУЛИРОВАНИЯ КУЛЬТУРЫ В РОССИЙСКОЙ ФЕДЕРАЦИИ НА СОВРЕМЕННОМ ЭТАПЕ
Creators: name: К. А. Южанинова
Publisher: name: Международный журнал гуманитарных и естественных наук
Year: 2019
Subjects: культурная сфера
культурная политика
принципы правового регулирования
государственное управление
исполнительная власть.

description: В настоящей статье автором рассматриваются важные на современном этапе развития для отечественного государства и права вопросы правового регулирования культурного сектора. Основное внимание было направлено на анализ и формирование системы общих принципов, характерных для всей отечественной правовой системы, в рамках настоящей статьи рассматриваются различные позиции современных правоведов по поводу исследуемой темы. В результате проведенного исследования сформирован исчерпывающий перечень основных и дополнительных общих исходных начал правового регулирования культуры, как составляющей системы принципов.
The Sacred Infrastructure for Computational Research
Creators: name: Greff, Klaus
name: Klein, Aaron
name: Chovanec, Martin
name: Hutter, Frank
name: Schmidhuber, Jürgen
Publisher: name: figshare
Year: 2018
Subjects: subject: 10299 Applied Mathematics not elsewhere classified
subject: FOS: Mathematics

description: We present a toolchain for computational research consisting of Sacred and two supporting tools. Sacred is an open source Python framework which aims to provide basic infrastructure for running computational experiments
independent of the methods and libraries used. Instead, it focuses on solving universal everyday problems, such as managing conﬁgurations, reproducing results, and bookkeeping. Moreover, it provides an extensible basis for other tools, two of which we present here: Labwatch helps with tuning hyperparameters, and Sacredboard provides a web-dashboard for organizing and analyzing runs
and results.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Cart. 188 (11 H 73), f. 0246r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0246r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0246r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Salt effects on knot dynamics in polyelectrolyte solutions
Creators: name: Gao, Xiangxiang
name: Xu, Xiaofei
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: We study the dynamics of linear polyelectrolyte (PE) knot in solution with doping salt by molecular dynamics simulations. The molecular mechanisms of PE knot dynamics are explained. The knot dynamics are the coupling results by the moving effect of chain entanglement and by the breathing effect of knot fluctuations. The moving effect is important as the whole chain is in the random coil state and becomes weak as shrinking to the close-to-globule (CTG) state. Interestingly, as the chain in the CTG state, the knot swells with occupying more segments. The breathing effect dominates the knot dynamics in the CTG state. This nontrivial behaviour (in comparison to neutral polymer knot) is prominent for the cases of doping salt with high concentration or of doping high-valent salt, which attributes to the enhanced electrostatic interactions and long-range fluctuation effects.
title: The Bibliographical Metadata Collection
title: A Guide for Contributors
titleType: Subtitle
Creators: name: Strotmann, Vivian
Publisher: name: Ruhr-Universität Bochum
Year: 2019

description: This Hoe Working Paper offers an overview of the functionalities of the websites of the HOE project, especially of the meta-data collection itself. It also provides a user guide for those who what to contribute data to the meta-data collection.
Molecular dynamics investigation of ivermectin bound to importin alpha/beta heterodimer
Creators: name: Sultana, Mossammad U. C.
name: Uddin, Md. Giash
name: Hossain, Md. Billal
name: Ali, Md Ackas
name: Sonia, Zannatul Ferdous
name: Kamal, Suprio
name: Halim, Mohammad A.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Ivermectin (D1), an FDA-approved drug, is mainly used as an inhibitor for the treatment of parasitic infections. This drug was drawn attention due to its effectiveness in COVID-19 treatment. In this work, we investigated how ivermectin and its analogues are interacted with Impα/β1 heterodimer by molecular docking, steered molecular dynamics (SMD), classical molecular dynamics (MD), and MM/PBSA binding free energy analysis. Docking results showed that ivermectin dimer showed the highest binding affinity of −12.2 kcal/mol compared to its monomer. In SMD, the highest acceleration of 600 pm/ps2 is noticed for D1-Impα/β1 complex in the distance from 18.27 to 18.36 Å. The pulling force of 1745.86 pN is also detected for D1-Impα/β1. To validate the docking and SMD results, 100 ns molecular dynamics (MD) simulation is performed on the D1-Impα/β1 complex. The average RMSD value indicates a good structural stability of the complex despite some significant changes at the beginning. It is noted that most of the residues are stable over the simulation time with an average RMSF value of less than 2.65 Å. The MM/PBSA free energy of ivermectin also shows strong and spontaneous binding with the Impα/β1.
ASFIXIOLOGIA FORENSE: A INVESTIGAÇÃO CRIMINAL ALICERÇADA NA MEDICINA LEGAL
Creators: name: Samuel Lucas Bezerra Tavares
name: Maria Mariana Cavalcante dos Santos Freitas
name: Abgail Clarice de Souza Ferreira
name: Larissa Soares Silva
name: Paulo Belisário Carvalho Cardoso Moitinho
name: Alexei José Esteves
Publisher: name: Zenodo
Year: 2021

description: RESUMO

 

Conforme a doutrina brasileira e os respectivos Códigos de Penal e Processo Penal, a Asfixiologia Forense é espécie do ramo da Traumatologia Forense. A primeira estuda as diversas possibilidades de asfixia, seja por sufocação, constrição cervical ou modificação do meio ambiente. Efetivamos análise jurídica, científica e social das diversas espécies mencionadas de asfixia, cumuladas com o ponto de vista investigativo, criminal e médico-legal do tema em questão.

 

Palavras-chave: Asfixia, medicina legal, investigação criminal, direito penal.
title: La Lesson Study :
title: de la théorie à la pratique. Analyse de l’impact des facilitateurs sur une Lesson Study en mathématique au niveau secondaire 1
titleType: Subtitle
title: La Lesson Study :
titleType: AlternativeTitle
Creators: name: Tedoldi, Amandine
name: King, Nicolas
Publisher: name: Unknown
Year: 0
Subjects: subject: Lesson Study
subject: facilitateur
subject: rôles
subject: confusions
subject: évaluation
subject: mathématiques

description: Le Laboratoire Lausannois de Lesson Study (3LS) mène chaque année des LS en formation continue dans les établissements vaudois. Dans ce mémoire, nous étudions le déroulement d’une de celle-ci en mathématiques au niveau secondaire 1. Les enseignants cherchent à créer un outil d’évaluation des apprentissages des élèves. Nous analysons la différence entre la théorie et la pratique d’une Lesson Study et donnons des éléments de réponses à la problématique suivante : Quel est l’impact des interventions ainsi que des choix organisationnels, didactiques et d’accompagnement des facilitateurs dans le déroulement d’une Lesson Study et sur la posture des enseignants ? Les enseignants participant à une LS doivent changer de posture et adopter, au minimum durant la LS, la position de chercheur. Pour cela les facilitateurs ont un rôle essentiel que ce soit dans la façon de structurer les séances ou dans la façon de communiquer des informations visant à accompagner les enseignants. Il est difficile de suivre un modèle théorique lorsque l’on est confronté aux réalités pratiques telles que les contraintes horaires, les motivations et agendas de chacun. Nous constatons qu’une posture ambigüe des facilitateurs entraîne un certain nombre de confusions chez les enseignants. Ces confusions sont visibles à travers la posture changeante des enseignants (praticiens et chercheurs), lors des apports méthodologiques des facilitateurs et lors des discussions didactiques (que ce soit sur les modalités de travail, les analyses de tâches ou l’élaboration d’outils d’évaluation). Bien que tous les aspects d’une Lesson Study ont été abordés le résultat final n’est pas transposable en l’état. La Lesson Study a besoin d’être effectuée plusieurs fois pour bien en assimiler les mécanismes et développer son plein potentiel.
Neural Expectation Maximization
Creators: name: Greff, Klaus
name: Steenkiste, Sjoerd Van
name: Schmidhuber, Jürgen
Publisher: name: figshare
Year: 2018
Subjects: subject: 10299 Applied Mathematics not elsewhere classified
subject: FOS: Mathematics

description: Many real world tasks such as reasoning and physical interaction require identiﬁcation and manipulation of conceptual entities. A ﬁrst step towards solving these
tasks is the automated discovery of distributed symbol-like representations. In this paper, we explicitly formalize this problem as inference in a spatial mixture model where each component is parametrized by a neural network. Based on the Expectation Maximization framework we then derive a differentiable clustering method that simultaneously learns how to group and represent individual entities.
We evaluate our method on the (sequential) perceptual grouping task and ﬁnd that it is able to accurately recover the constituent objects. We demonstrate that the
learned representations are useful for next-step prediction.
MacDonald_etal_Readme.pdf
Creators: name: MacDonald, Kelly
name: Leroux, Shawn J
name: Purchase, Craig F.
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60204 Freshwater Ecology

description: This file contains information about the code and datasets in this project, associated with
K.J. MacDonald, C. F. Purchase, S.J. Leroux [Submitted for Review]. Landscape, demographic, and dispersal parameters influence the spread and establishment dynamics of an aquatic biological invasion.
Ética profissional, deontologia e sindicalismo na biblioteconomia brasileira
Creators: name: Jessé Albino Santana
name: Nunes, Jefferson Veras
Publisher: name: figshare
Year: 2018
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications
subject: 80706 Librarianship

description: Tem como objetivo abordar a relação entre ética profissional, deontologia e organização sindical na Biblioteconomia brasileira. Na metodologia utiliza como coleta de dados a pesquisa bibliográfica e documental. Apresenta conceitos referentes à ética como ciência e de sua importância no âmbito das profissões. Relaciona ética e deontologia, entendendo esta como ciência do dever, responsável de averiguar como surgem e se sustentam as normas orientadoras das classes de profissionais. Evoca elementos históricos do movimento sindical na Inglaterra, sua chegada ao Brasil e início da sindicalização dos bibliotecários brasileiros. Como resultado, destaca a necessidade de ampliar os debates em torno da ética profissional e do amadurecimento da consciência de classe dos bibliotecários, o que poderá repercutir em ações coletivas de maior visibilidade junto à sociedade.
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00171
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CBMA/CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00171, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Análise documental de imagem: uma leitura das contribuições semióticas
Creators: name: Gatto, Ana Clara
Publisher: name: figshare
Year: 2018
Subjects: subject: 80706 Librarianship
subject: FOS: Media and communications
subject: Library and Information Studies

description: Analisando a imagen como objeto de estudo científico e sendo compreendida como documento, o presente artigo busca realizar uma revisão acerca dos estudos sobre análise documental e análise de conteúdo da Imagem em imagens fotográficas, artísticas e midiáticas, para fins de indexação. A metodologia utilizada será qualitativa com caráter descritivo e objetiva apresentar as principais contribuições na área da semiótica visual. Conclui-se que a análise documental junto com as teorías semióticas, compreende as imagens como documento e, por meio da indexação, torna-o disseminado e recuperado.
Effects of Croton lechleri sap (Sangre de Drago) on AGEs formation, LDL oxidation and oxidative stress related to vascular diseases
Creators: name: Chen, Zheng
name: Bertin, Riccardo
name: Marin, Raffaella
name: Djeujo, Francine Medjiofack
name: Froldi, Guglielmina
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: The sap of Croton lechleri Müll. Arg. (Euphorbiaceae) is well-known in South American traditional medicine. This research investigated its activity against glycation and oxidative stress (glycoxidation) to estimate its usefulness in ROS-related diseases. The activity of the sap on albumin glycation, LDL oxidation and ROS formation was detected. C. lechleri sap inhibited BSA glycation and exhibited a protective effect against LDL oxidation; at the concentration of 0.8 µg/mL, it extended the Lag phase of almost 60%. Furthermore, the sap was studied on cell viability and ROS production in HUVEC showing valuable free-radical scavenging activity. In detail, the sap (1.0 and 10.0 μg/mL) significantly decreased the baseline level and H2O2-induced ROS production in HUVEC. This research showed for the first time the ability of C. lechleri sap to decrease the albumin glycation, LDL oxidation and ROS formation in HUVEC, supporting its potential in vascular diseases.
2024: Current Stem Cell Therapy for Osteoarthritis
Creators: name: Habiba, Umm E
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320216
subject: Orthopaedics
classificationCode: 320223
subject: Rheumatology and arthritis
classificationCode: 320225
subject: Sports medicine
classificationCode: 320218
subject: Pain

description: This work describes the active stem cell treatment centers working globally in Osteoarthritis. This report also displays the patient testimonials and describes the success of stem cell therapy.
Phytochemical and antiplasmodial investigation of Gardenia thunbergia L. f. leaves
Creators: name: Tajuddeen, Nasir
name: Swart, Tarryn
name: Hoppe, Heinrich C.
name: van Heerden, Fanie R.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Virology

description: Previous results indicated that the methanol extract of Gardenia thunbergia has antiplasmodial activity but no compounds have ever been isolated from the plant. Therefore, this study aimed to investigate the phytochemical and antiplasmodial properties of the plant. The methanol leaf extract of G. thunbergia inhibited Plasmodium falciparum at 50 µg/mL (> 80% inhibition) and was not cytotoxic against HeLa cells. Chromatographic purification of the extract afforded a new saponin and eight other known compounds. The saponin and two flavonoid glycosides displayed non-selective antiplasmodial activity at 50 µg/mL but the activities were diminished at 10 µg/mL. The presence of the isolated compounds in the leaf extract of G. thunbergia could account for the folkloric use of the plant in treating malaria.