cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Symptomatic pes planus in children: A synthesis of allied health professional practices
Creators: name: SC Morrison
name: M Tait
name: E Bong
name: KJ Kane
name: Nester, Christopher
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Author(s). Background: This study sought to explore professional perspectives on the assessment and management of symptomatic pes planus in children. Methods: Data was collected from three professional groups (podiatrists, physiotherapists, and orthotists) with experience of managing foot problems in children. The survey was undertaken in the United Kingdom via a self-administered, online survey. Data was captured over a four-month period in 2018. Results: Fifty-five health professionals completed the survey and the results highlighted that assessment techniques varied between professions, with standing tip-toe and joint range of motion being the most common. Treatment options for children were diverse and professionals were adopting different strategies as their first line intervention. All professions used orthoses. Conclusions: There were inconsistencies in how the health professionals assessed children presenting with foot symptoms, variation in how the condition was managed and differences in outcome measurement. These findings might be explained by the lack of robust evidence and suggests that more effort is needed to harmonise assessment and treatment approaches between professions. Addressing discrepancies in practice could help prioritise professional roles in this area, and better support the management of children with foot pain.
Additional file 1 of Effects of gender-affirming hormone therapy on body fat: a retrospective case‒control study in Chinese transwomen
Creators: name: Pei, Qin
name: Song, Yuwei
name: Huang, Zhongwei
name: Yu, Hongkun
name: Xu, Hao
name: Ye, Xunda
name: Gao, Lvfen
name: Gong, Jian
name: Tian, Xiaoying
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology
subject: Cardiology

description: Supplementary Material 1
Busulfan/Sulfolane metabolic ratio on the third day of conditioning may predict the event-free survival in children receiving busulfan based conditioning prior to hematopoietic stem-cell transplantation
Creators: name: Chakradhara Rao S Uppugunduri
name: Rezgui, Aziz
name: Curtis, Patricia Huezo-Diaz
name: Nava, Tiago
name: Mlakar, Simona
name: Theoret, Yves
name: Bittencourt, Henrique
name: Krajinovic, Maja
name: Ansari, Marc
Publisher: name: Zenodo
Year: 2019
Subjects: busulfan
sulfolane
efficacy
metabolic ratio
HSCT
Pediatrics

description: EBMT 2019 meeting abstract : https://www.professionalabstracts.com/ebmt2019/programme-ebmt2019.pdf ESDPPP 2019 meeting abstract; https://adc.bmj.com/content/104/6/e57.2
Deep Learning for Segmentation Of 3D Cryo-EM Images
Creators: name: Haslam, Devin Reid
Publisher: name: Old Dominion University Libraries
Year: 2018

description: Cryo-electron microscopy (cryo-EM) is an emerging biophysical technique for structural determination of protein complexes. However, accurate detection of secondary structures is still challenging when cryo-EM density maps are at medium resolutions (5-10 Å). Most existing methods are image processing methods that do not fully utilize available images in the cryo-EM database. In this paper, we present a deep learning approach to segment secondary structure elements as helices and β-sheets from medium- resolution density maps. The proposed 3D convolutional neural network is shown to detect secondary structure locations with an F1 score between 0.79 and 0.88 for six simulated test cases. The architecture was also applied to experimentally-derived cryo- EM density regions of 571 protein chains. . The average F1 score for helix detection is 0.747 and 0.674 for β-sheets in a test involving seven cryo-EM density regions. Additionally, we extend an arc-length association method to β -strands and show that this method for measuring error is superior to many popular methods. An interactive tool is also presented that can visualize the results of this arc-length association method.
Neoascochyta zhejiangensis Y. Wang, Y. Tu, X. Chen, H. Jiang, H. Ren, Q. Lu, C. Wei & W. Lv 2024, sp. nov.
Creators: name: Wang, Yuchun
name: Tu, Yiyi
name: Chen, Xueling
name: Jiang, Hong
name: Ren, Hengze
name: Lu, Qinhua
name: Wei, Chaoling
name: Lv, Wuyun
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Pleosporales
Didymellaceae
Neoascochyta
Neoascochyta zhejiangensis

description: Neoascochyta zhejiangensis Y. Wang, Y. Tu, X. Chen, H. Jiang, H. Ren, Q. Lu, C. Wei & W. Lv sp. nov.
Fig. 10
Etymology.
Named after the location where it was collected, Zhejiang Province.
Description.
 Sexual morph: undetermined. Asexual morph: Pycnidia smooth, subglobose to ellipsoidal, hyaline. Conidia biconical to subcylindrical, hyaline, smooth- and thin-walled, abundant, generated from pycnidia, aseptate, 4.8–6.5 × 2.9–4.2 µm (av. = 5.6 ± 0.5 × 3.6 ± 0.3 µm, n = 30). Mycelia lateral branching or uniaxial branching, septate, hyaline.
Culture characteristics.
Colonies on PDA reaching 65–69 mm diam. after 7 days at 28 ° C in the dark, margin regular, aerial mycelium flat, whitish; reverse black, white edges. Pycnidia and conidia produced on the colony surface after being cultured for 14 days at 28 ° C in the dark. Colonies on OA reaching 53–57 mm diam. after 7 days at 28 ° C in the dark, margin regular, aerial mycelium flat, whitish; reverse olivaceous, white edges.
Materials examined.
 China, Zhejiang Province, Hangzhou City, from diseased leaves of C. sinensis cv. Longjing 43, Jun 2014, Y. C. Wang, Holotype HMAS 352392, culture ex-type CGMCC 3.24250 = YCW 1107. Yunnan Province, from diseased leaves of C. sinensis, 23 Mar 2020, Y. C. Wang, culture CGMCC 3. YCW 1361.
Notes.
 Neoascochyta zhejiangensis is closely related to N. cylindrispora with high statistical support (82 % / 77, ML / PP, Fig. 4). Neoascochyta Cylindrispora differs in 1 bp in ITS, 16 bp in TUB 2 and 95 bp in LSU from N. zhejiangensis. In the present study, two strains were isolated from healthy tea plant leaves.
description: Published as part of Wang, Yuchun, Tu, Yiyi, Chen, Xueling, Jiang, Hong, Ren, Hengze, Lu, Qinhua, Wei, Chaoling & Lv, Wuyun, 2024, Didymellaceae species associated with tea plant (Camellia sinensis) in China, pp. 217-251 in MycoKeys 105 on pages 217-251, DOI: 10.3897/mycokeys.105.119536
Astrosarkus Mah 2003
Creators: name: Mah, Christopher L.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Valvatida
Oreasteridae
Astrosarkus

description: Astrosarkus Mah 2003
 Diagnosis. Body pentagonal to weakly stellate, R/r=1.25–1.4. Arms and disk confluent with rounded arm tips, with thick smooth, soft “flesh” imbued with channels through the body wall; highly modified abactinal, marginal and actinal plates. Surface has continuous granular cover. Larger accessory structures present or absent. Papular areas extensive on discrete mound-like regions on abactinal, lateral surface. Internal, fixed, spine-like processes on ambulacrals. Furrow spines 10– 11, subambulacral spines, 2–5. Modified from Mah (2003).
 Comments. This account reports on new specimens and observations from Australian as well as other Indian Ocean localities. At the time of description, known distribution was limited to the tropical South Pacific to Reunion Island. Astrosarkus is now known to be widely distributed at mesophotic depths throughout the tropical Indo-Pacific (30– 150 m), including southern Japan and Guam (Kogure et al., 2009) to the Marshall Islands /South Pacific, the coast of northern Australia (Queensland and Western Australia) and the western Indian Ocean (Reunion Island, Mayotte, Maldives).
description: Published as part of Mah, Christopher L., 2023, A new species of Astrosarkus from Western Australia including new Mesophotic occurrences of Indian Ocean Oreasteridae (Valvatida, Asteroidea), pp. 143-165 in Memoirs of Museum Victoria 82 on page 144, DOI: 10.24199/j.mmv.2023.82.08, http://zenodo.org/record/12214383
Additional file 2 of Effects of gender-affirming hormone therapy on body fat: a retrospective case‒control study in Chinese transwomen
Creators: name: Pei, Qin
name: Song, Yuwei
name: Huang, Zhongwei
name: Yu, Hongkun
name: Xu, Hao
name: Ye, Xunda
name: Gao, Lvfen
name: Gong, Jian
name: Tian, Xiaoying
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology
subject: Cardiology

description: Supplementary Material 2
Professional appraisal of online information about children's footwear measurement and fit: Readability, usability and quality
Creators: name: C Price
name: M Haley
name: A Williams
name: Nester, Christopher
name: SC Morrison
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Author(s). Background: Parents increasingly use the internet to seek health information, share information and for purchasing textiles and footwear. This shift in footwear purchasing habits raises concern about how (and if) parents are getting their children's feet measured, and what support strategies are in place to support the fit of footwear. In response to this, some companies and healthcare organisations have developed resources to support home measurement of foot size, and link these measures to footwear selection, measurement and fitting. The aim of this research was to undertake an appraisal of web-based resources about measurement and fit of children's footwear, focussing specifically on readability, usability and quality. Methods: Search terms relating to children's foot measurement were compiled and online searching was undertaken. Search results were saved and screened for relevance. Existing resources were categorised based on their source e.g. a footwear company or a health website. The 15 most commonly identified resources were reviewed by a professional panel for readability, content, usability and validity. One researcher also assessed the accessibility and reading ease of the resources. Results: Online resources were predominantly from commercial footwear companies (54%). Health information sources from professional bodies made up 4.2% of the resources identified. The top 15 resources had appropriate reading ease scores for parents (SMOG Index 4.3-8.2). Accessibility scores (the product of the number of times it appeared in search results and its ranking in the results) were highest for commercial footwear companies. The panel scores for readability ranged from 2.7 to 9 out of 10, with a similar range for content, usability and validity. Conclusions: Information for parents seeking to purchase footwear for their children is readily available online but this was largely dominated by commercial footwear companies. The quality and usability of this information is of a moderate standard; notable improvements could be made to the validity of the task the child is asked to undertake and the measures being taken. Improvements in these resources would improve the data input to the selection of footwear and therefore have a beneficial impact on footwear fit in children.
The evolution of the Kuna Mola: from cultural authentication to cultural survival
Creators: name: Marks, Diana
Publisher: name: RMIT University
Year: 2024

description: The San Blas Kuna Indians, an American Indian indigenous people, live in an autonomous territory in Panama and are considered to be a micro island nation. The distinctive mola blouse worn by Kuna women is recognised as an identifier of the Kuna people and also of Panama, and the history of this dual symbolism is investigated through an interdisciplinary approach. A “reference collection” comprising molas from six museums provided the basis for understanding the evolution of molas over the last one hundred years. A visual analysis comparing molas in these museums with contemporaneous archival photographs prompted an investigation of the role of the mola in Kuna culture, since the iconography of the mola panels is obscured when worn as part of the dress ensemble of Kuna women. The conceptual framework developed for this dissertation comprised four elements: cultural authentication; flow theory; cultural survival; and identity. The origin of the mola is explained in terms of the concept of cultural authentication developed by Eicher and Erekosima (1980) and this is linked to the concept of the invention of tradition (Hobsbawm and Ranger, 1983). Each of the components of cultural authentication outlined by Eicher and Erekosima was found to occur. The motivation for the continuation of the high quality mola production can be explained by a combination of factors, which relate to Csikszentmihalyi’s Flow Theory and the central role of ritual, which are linked to positive well-being. Previous research has established a link between textile making activities and the well-being of women in Western cultures and this research confirms that the theory is applicable to non-Western culture.

 The concept of ‘serious leisure’ is also found to be relevant to non-Western culture. The continuation of mola production is also considered in the context of the cultural survival of ethnic nation-states and the concept of ‘islamiento’, developed by Chernela (2011), is extended to encompass the overarching strategy developed by Kuna leaders since the move of the Kuna people to the San Blas islands, during the second half of the 19th century. This dissertation explores the reasons why the mola developed during the first part of the 20th century as part of the everyday dress ensemble of Kuna women, and why after the Kuna Revolution in 1925, the role of the mola in creating Kuna identity was reinforced. The association of the mola with Panama has in recent years also created a market for the mola as a tourist souvenir. Finally, the dissertation examines the role of museums in preserving Kuna material culture, which is not possible under local conditions. This dissertation concludes that museum collections are an integral part of a strategy to ensure cultural continuity and survival. Museum collections provide an important resource, vital for researchers from Kuna Indian communities, to trace the evolution of mola design and the significance of the mola for cultural identity.
Additional file 3 of Effects of gender-affirming hormone therapy on body fat: a retrospective case‒control study in Chinese transwomen
Creators: name: Pei, Qin
name: Song, Yuwei
name: Huang, Zhongwei
name: Yu, Hongkun
name: Xu, Hao
name: Ye, Xunda
name: Gao, Lvfen
name: Gong, Jian
name: Tian, Xiaoying
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology
subject: Cardiology

description: Supplementary Material 3
Paraboeremia litseae J. R. Jiang
Creators: name: Wang, Yuchun
name: Tu, Yiyi
name: Chen, Xueling
name: Jiang, Hong
name: Ren, Hengze
name: Lu, Qinhua
name: Wei, Chaoling
name: Lv, Wuyun
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Pleosporales
Didymellaceae
Paraboeremia
Paraboeremia litseae

description: Paraboeremia litseae J. R. Jiang et al., Mycological Progress. 16: 291. 2017
Description.
see Jiang et al. (2017).
Materials examined.
 China, Yunnan Province, from diseased leaves of C. sinensis, 23 Mar 2020, Y. C. Wang, culture YCW 1356 and culture YCW 1363.
Notes.
 Isolates of Paraboeremia litseae clustered into a sister clade to P. selaginellae (Fig. 5). It was first isolated from Litsea sp. (Jiang et al. 2017). Conidia produced by P. litseae are oblong to ellipsoidal and aseptate with two large polar guttules (Jiang et al. 2017). This species as an endophytic fungus in Coptis chinensis exhibited obvious inhibition against methicillin-resistant Staphylococcus aureus (Ming et al. 2022). In the present study, two strains were isolated from diseased tea plant leaves. This is the first report of P. litseae causing leaf blight on C. sinensis.
description: Published as part of Wang, Yuchun, Tu, Yiyi, Chen, Xueling, Jiang, Hong, Ren, Hengze, Lu, Qinhua, Wei, Chaoling & Lv, Wuyun, 2024, Didymellaceae species associated with tea plant (Camellia sinensis) in China, pp. 217-251 in MycoKeys 105 on pages 217-251, DOI: 10.3897/mycokeys.105.119536
Protecting web servers from distributed denial of service attack
Creators: name: Sivabalan, Sujatha
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 400604
subject: Network engineering
classificationCode: 460407
subject: System and network security
classificationCode: 460609
subject: Networking and communications
classificationCode: 460612
subject: Service oriented computing

description: This thesis developed a novel architecture and adaptive methods to detect and block Distributed Denial of Service attacks with minimal punishment to legitimate users. A real time scoring algorithm differentiated attackers from
legitimate users. This architecture reduces the power consumption of a web server farm thus reducing the carbon footprint.
Additional file 2 of Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study
Creators: name: Miao, Lusheng
name: Miao, Taosheng
name: Zhang, Ying
name: Hao, Jin
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Mental Health

description: Additional file 2 Overview of the study design. eQTLs, expression quantitative trait loci; GWAS, genome-wide association study; LDL-C, low-density lipoprotein cholesterol; HMGCR, 3-Hydroxy-3-Methylglutaryl-CoA Reductase; PCSK9, Proprotein convertase subtilisin/kexin type 9; NPC1L1, NPC1 Like Intracellular Cholesterol Transporter 1; MR, Mendelian randomization; SMR, Summary data-based Mendelian randomization; HEIDI, heterogeneity in dependent instruments; IVW, inverse-variance weighted; WM, Weighted median
Enhancing computational fluid dynamics modelling using intelligent systems technology
Creators: name: Becker, William
Publisher: name: RMIT University
Year: 2024

description: Computational Fluid Dynamic simulations take a long time to run, yet the results that these simulations produce is required quickly in user interfaces and optimisation routines. One solution to this is preprocessing the simulations and using this as the basis of some interpolation methodology, such as neural networks. However creating such a system is not a simple task. A trade off needs to be made between the quality of the simulations run and thus the speed at which simulations can be generated; the number of simulations run and the time allocated to gathering data; the amount of inputs to interpolate over and the complexity of the system. This is complicated by the fact that simulations are difficult to run and monitor and thus can be hard to generally automate. Furthermore, merely running more simulations is not necessarily useful: the parameters used to run a simulation are critical to improve the interpolation ability of the prediction methodology, especially when dealing with more than a small number of inputs.

This thesis proposes a system, CFDLearner, which is a framework that attempts to break this problem down into a number of modules that then can be independently solved. It deals with the execution, monitoring and extraction of data from simulations, the generation of parameters with which a simulation is run and the learning of the results generated to create an ``expert surveyor' which is capable of quickly estimating the results gained from the simulations. Furthermore a visualisation tool is generated which provides a means of assessing the confidence of the interpolated results and allows for the optimisation of outputs. To accomplish this task, new techniques are proposed in the fields of neural networks, parameter selection and knowledge based systems.

CFDLearner has been used with the Fire Dynamics Simulator to simulate single compartment house fires. The advantages of the novel neural network methodologies used and the adaptive parameter selection scheme are presented. Furthermore the utility of CFDLearner is demonstrated in its graphical ability to interactively allow users to simply navigate through hundreds of simulation results with multiple input and output parameters. This allows non-expert users to simply obtain useful information about complex simulations without having to understand the underlying complexity that it takes to generate and collate such data.
Satellite Image Map West-Neuschwabenland 1:3 000 000 1982, Antarktis
Creators: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Publisher: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Year: 1982
Subjects: Antarctica
Satellite image mosaic
Ice front
Dronning Maud Land
Neuschwabenland
Riiser-Larsenisen
Camp Norvegia 3 and 4
Kapp Norvegia
Ritscherhochland
Ekströmisen
Atka Iceport
Atkabukta
Station Georg von Neumayer (DE)
Wegenerinlandeis
Jutulstraumen
Fimbulisen
Station SANAE (ZA)
Mühlig-Hofmann-Gebirge
Wohlthatmassiv
Novolazarevskaja
Schirmacheroase
Sør Rondane

description: Satellite image mosaic, NOAA-6 and 7-AVHRR, Records taken from Dec 1981 to March 1982, Geometrically rectified using 19 ground control points, 500m-contours on the mainland taken from GEBCO Chart 5.18 at 1.6 000 000 scale, 1980; Map graticule, Inset maps: Location diagram, Imagery coverage diagramScale: 1:3000000;Projection: Polar Stereographic;Bounding Box: POLYGON ((-15 -68.5, 25 -68.5, 30 -72.5, 11 -74.5, 11 -76, -20 -76, -15 -68.5))
Conservative treatment for acute ankle sprain: a systematic review
Creators: name: Ortega-Avila, Ana Belen
name: Cervera-Garvi, Pablo
name: Marchena-Rodriguez, Ana
name: Chicharro-Luna, Esther
name: Nester, Christopher
name: Starbuck, Chelsea
name: Gijon-Nogueron, Gabriel
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The aim was to identify conservative treatments available for acute ankle sprain and to evaluate their effectiveness with respect to pain relief and short-term recovery of functional capacity. A systematic review of the relevant literature was conducted via a data search of the PROSPERO, PubMed, Scopus, CINAHL, PyscINFO and SPORTDiscus databases, from inception until December 2019, focusing on randomised control trial studies. Two of the authors independently assessed the quality of each study located and extracted the relevant data. The quality of each paper was assessed using the Cochrane risk of bias tool included in RevMan 5. In all, 20 studies met the inclusion criteria. In terms of absence of bias, only nine papers were classed as “high quality”. Studies (75%) were of low quality in terms of the blinding of participants and personnel and uncertainty in blinding of outcome assessment and all presented one or more other forms of bias. Despite the generally low quality of the studies considered, it can be concluded that conservative treatment for acute ankle sprain normally achieves pain relief and rapidly improved functionality. Research based on higher-quality study designs and procedures would enable more definitive conclusions to be drawn.
Cemcap Economic Model Spreadsheet
Creators: name: Lena, Edoardo De
name: Marizio Spinelli
name: Romano, Matteo
name: Gardarsdottir, Stefania Osk
name: Roussanaly, Simon
name: Voldsund, Mari
Publisher: name: Zenodo
Year: 2018
Subjects: Co2 capture
cement
economic evaluation
cost of cement
cost of CO2 avoided

description: Excel spreadsheet for calcualtion of cost of clinker and cost of CO2 avoided for CO2 capture in the cement industry.
Carer experience of end-of-life service provision: a social network analysis
Creators: name: R Leonard
name: D Horsfall
name: Rosenberg, John
name: K Noonan
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2020. Objective To identify the position of formal service providers in the networks of those providing end-of-life care in the home from the perspective of the informal network. Methods Using third-generation social network analysis, this study examined the nature and strength of relationships of informal caring networks with formal service providers through individual carer interviews, focus groups of caring networks and outer network interviews. Results Service providers were usually highly valued for providing services, equipment, pain management and personalised care for the dying person plus support and advice to the principal carer about both caring tasks and negotiating the health system. However, formal service providers were positioned as marginal in the caring network. Analysis of the relative density of relationships within networks showed that whereas relationships among family and friends had similar density, relationships between service providers and family or friends were significantly lower. Conclusion The results supported the Circles of Care model and mirror the perspective of formal service providers identified in previous research. The research raises questions about how formal and informal networks might be better integrated to increase their effectiveness for supporting in-home care.
Comparing older people's drinking habits in four Nordic countries: Summary of the thematic issue
Creators: name: Tigerstedt, Christoffer
name: Agahi, Neda
name: Bye, Elin
name: Ekholm, Ola
name: Harkonen, Janne
name: Jensen, Heidi Rosendahl
name: Lau, Cathrine Juel
name: Makela, Pia
name: Moan, Inger Synnove
name: Parikka, Suvi
name: Raninen, Jonas
name: Vilkko, Anni
name: Bloomfield, Kim
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © The Author(s) 2020. Aim: The present article summarises status and trends in the 21st century in older people’s (60–79 years) drinking behaviour in Denmark, Finland, Norway and Sweden and concludes this thematic issue. Each country provided a detailed report analysing four indicators of alcohol use: the prevalence of alcohol consumers, the prevalence of frequent use, typical amounts of use, and the prevalence of heavy episodic drinking (HED). The specific aim of this article is to compare the results of the country reports. Findings: Older people’s drinking became more common first in Denmark in the 1970s and then in the other countries by the 1980s. Since 2000 the picture is mixed. Denmark showed decreases in drinking frequency, typically consumed amounts and HED, while in Sweden upward trends were dominant regarding prevalence of consumers and frequency of drinking as well as HED. Finland and Norway displayed both stable indicators except for drinking frequency and proportion of women consumers where trends increased. In all four countries, the gender gap diminished with regard to prevalence and frequency of drinking, but remained stable in regard to consuming large amounts. In Norway the share of alcohol consumers among women aged 60–69 years exceeded the share among men. During the late 2010s, Denmark had the highest prevalence of alcohol consumers as well as the highest proportion drinking at a higher frequency. Next in ranking was Finland, followed by Sweden and Norway. This overall rank ordering was observed for both men and women. Conclusion: As the populations aged 60 years and older in the Nordic countries continue to grow, explanations for the drivers and consequences of changes in older people’s drinking will become an increasingly relevant topic for future research. Importantly, people aged 80 years and older should also be included as an integral part of that research.
Additional file 5 of Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study
Creators: name: Miao, Lusheng
name: Miao, Taosheng
name: Zhang, Ying
name: Hao, Jin
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Mental Health

description: Additional file 5 The flowchart of the selection of instrumental variables (IVs) in IVW-MR. LDL-C, low-density lipoprotein cholesterol; GWAS, genome-wide association study; HMGCR, 3-Hydroxy-3-Methylglutaryl-CoA Reductase; PCSK9, Proprotein convertase subtilisin/kexin type 9; NPC1L1, NPC1 Like Intracellular Cholesterol Transporter 1; CM, cutaneous melanoma; MR, Mendelian randomization; CHD, coronary heart disease.
Chondrophycus planiparvus Popolizio, C. W. Schneider & C. E. Lane 2022, sp. nov.
Creators: name: Popolizio, Thea R.
name: Schneider, Craig W.
name: Jongbloed, Walter M.
name: Saunders, Gary W.
name: Lane, Christopher E.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Rhodophyta
Florideophyceae
Ceramiales
Rhodomelaceae
Chondrophycus
Chondrophycus planiparvus

description: Chondrophycus planiparvus Popolizio, C.W.Schneider & C.E.Lane, sp. nov.   (Fig. 5)
 HOLOTYPE. — T.R. Popolizio / C.W. Schneider 12-40-13 (BDA0934), 13.III.2012, Gurnet Rock, mouth of Castle Harbour, Bermuda, western Atlantic Ocean, 32°20’22.7”N, 64°39’44.8”W, depth 13 m [deposited in UNB]; iso-, MICH [TRP 12-40-12 (BDA0933)].
 HOLOTYPE DNA BARCODE. — GenBank OK209884, COI-5P; OK209859, rbc L.
 PARATYPES. — Bermuda. CWS/CEL 09-30-9, 19.III.2009, Gurnet Rock, loc. cit., 32°20’20.2”N, 64°39’32.1”W, depth 16-17 m; TRP/ CWS 12-148-6 [BDA1625], 5.XI.2012, wreck of the Pelinaion, north shore Bermuda I., 32°21’20.9”N, 64°38’36.9”W, depth 18 m; TRP/CWS 12-160-8 [BDA1741], 1.XII.2012, wreck of the Hermes, south shore Bermuda I., 32°14’42.4”N, 64°48’00.1”W, depth 23 m.
 ETYMOLOGY. — From the Latin, describing the typical habit of this flattened (‘ planus ’) and relatively small (‘ parvus ’) species.
DISTRIBUTION. — Endemic to Bermuda as presently known.
SEASONALITY. — Collected from November to March in Bermuda.  DESCRIPTION
Plants to 2 cm high, distinctly compressed, rosy-red, cartilaginous (Fig. 5 A-D); main axes to 2 mm diam. with one or more arising from discoidal holdfasts; branching irregular to opposite or alternate, with branch apices sometimes appearing trifurcated (Fig. 5B, D); branchlets to 2 mm in diam. Vegetative axes with 2 pericentral cells; cortical cells arranged longitudinally in surface view (Fig. 5E, H), secondary pit connections abundant (Fig. 5G, H). In transverse section, non-palisade outer cortical cells, obtriangulate to obovate, with constrictions at the base (Fig. 5G), 12-35 µm diam. and 9-27 µm long, some acute projections present at branch apices in surface view; outer cortical cells ovoid in upper branch regions, irregularly angular and elongated below, 9-55 µm diam. and 20-100 µm long (Fig. 5H); lenticular thickenings absent in the walls of medullary cells. Extensive trichoblasts emerging from shallow apical pits (Fig. 5F), dichotomously branched, to 600 µm long. Tetrasporangia forming at apices, slightly ovoid, arranged at right angles to the axis (Saito 1967: 71), 43-68 µm diam. and 48-96 µm long (Fig. 5I). Gametangia not found.
description: Published as part of Popolizio, Thea R., Schneider, Craig W., Jongbloed, Walter M., Saunders, Gary W. & Lane, Christopher E., 2022, Molecular analysis resolves the taxonomy of the Laurencia complex (Rhodomelaceae, Ceramiales) in Bermuda and uncovers novel species of Chondrophycus and Laurenciella, pp. 1-30 in Cryptogamie, Algologie 20 (1) on page 8, DOI: 10.5252/cryptogamie-algologie2022v43a1
Evaluating the effectiveness of pulsed electromagnetic field stimulation on bone fracture-related healing through in vitro experiments and computational modelling
Creators: name: Daish, Christian
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 400302
subject: Biomaterials
classificationCode: 400305
subject: Biomedical instrumentation
classificationCode: 401706
subject: Numerical modelling and mechanical characterisation

description: Bone fractures are one of the most commonly occurring injuries of the musculoskeletal system. A highly physiological process, fracture healing has been studied extensively. Data from in vivo, in vitro, and clinical studies have shown exposure to pulsed electromagnetic fields (PEMFs) to be influential in the fracture repair process. It has been a challenge to determine which PEMF exposure parameters (i.e., frequency of field, intensity of field, and exposure duration) will produce the most effective repair, due to the complexity of the repair process, involving many components acting at different time steps, and the variation in patient biology and physiology. Conclusively determining such parameters requires: ensuring the exposure being produced is consistent and homogeneous through field simulations and development of a device adequate to produce such a field, and: validating the exposure and its effects through cellular experimentations and computational modelling. In this PhD project, these tools were applied, first through the design and development of a device which was then subsequently used for the testing of field effects on stem cells in vitro, and then through the development of a novel wearable therapeutic prototype to be used in clinical studies for accelerated fracture repair-related processes. Through the application of such tools, an optimal exposure condition was found that significantly, above others, influenced the proliferation of stem cells. A major finding of this research was that fracture repair studies performed in vitro have limitations and as such it is recommended that more research be performed into the mechanisms of action of PEMF effects; similar experiments as those applied herein be performed at the in vivo scale; and further more anatomically similar (i.e., 3D) computational models be built stemming from those developed in this project.
A compendium of ecological knowledge for restoration of freshwater fishes in Australia's Murray-Darling Basin
Creators: name: JD Koehn
name: SM Raymond
name: I Stuart
name: CR Todd
name: Balcombe, Stephen
name: BP Zampatti
name: H Bamford
name: BA Ingram
name: CM Bice
name: K Burndred
name: G Butler
name: L Baumgartner
name: P Clunie
name: I Ellis
name: JP Forbes
name: M Hutchison
name: WM Koster
name: M Lintermans
name: JP Lyon
name: M Mallen-Cooper
name: M McLellan
name: L Pearce
name: J Ryall
name: C Sharpe
name: DJ Stoessel
name: JD Thiem
name: Z Tonkin
name: A Townsend
name: Q Ye
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 Journal Compilation Many freshwater fishes are imperilled globally, and there is a need for easily accessible, contemporary ecological knowledge to guide management. This compendium contains knowledge collated from over 600 publications and 27 expert workshops to support the restoration of 9 priority native freshwater fish species, representative of the range of life-history strategies and values in south-eastern Australia's Murray-Darling Basin. To help prioritise future research investment and restoration actions, ecological knowledge and threats were assessed for each species and life stage. There is considerable new knowledge (80% of publications used were from the past 20 years), but this varied among species and life stages, with most known about adults, then egg, juvenile and larval stages (in that order). The biggest knowledge gaps concerned early life stage requirements, survival, recruitment, growth rates, condition and movements. Key threats include reduced longitudinal and lateral connectivity, altered flows, loss of refugia, reductions in both flowing (lotic) and slackwater riverine habitats, degradation of wetland habitats, alien species interactions and loss of aquatic vegetation. Examples and case studies illustrating the application of this knowledge to underpin effective restoration management are provided. This extensive ecological evidence base for multiple species is presented in a tabular format to assist a range of readers.
What is needed to restore native fishes in Australia's Murray-Darling Basin?
Creators: name: JD Koehn
name: Balcombe, Stephen
name: LJ Baumgartner
name: CM Bice
name: K Burndred
name: I Ellis
name: WM Koster
name: M Lintermans
name: L Pearce
name: C Sharpe
name: I Stuart
name: CR Todd
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 Journal Compilation The Murray-Darling Basin (MDB) is Australia's food bowl, contributing 40% of agricultural production and supporting a population of over 4 million people. Historically, the MDB supported a unique native fish community with significant cultural, subsistence, recreational, commercial and ecological values. Approximately one-quarter of the MDB's native species are endemic. Changes to river flows and habitats have led to a >90% decline in native fish populations over the past 150 years, with almost half the species now of conservation concern. Commercial fisheries have collapsed, and important traditional cultural practices of First Nations People have been weakened. The past 20 years have seen significant advances in the scientific understanding of native fish ecology, the effects of human-related activities and the recovery measures needed. The science is well established, and some robust restoration-enabling policies have been initiated to underpin actions. What is now required is the political vision and commitment to support investment to drive long-term recovery. We present a summary of 30 priority activities urgently needed to restore MDB native fishes.
Temporal analysis of Brd4 displacement in the control of B Cell survival, proliferation, and differentiation
Creators: name: IY Kong
name: JS Rimes
name: A Light
name: I Todorovski
name: S Jones
name: E Morand
name: DA Knight
name: YE Bergman
name: SJ Hogg
name: H Falk
name: BJ Monahan
name: PA Stupple
name: IP Street
name: Heinzel, Susanne
name: P Bouillet
name: RW Johnstone
name: Hodgkin, Philip
name: SJ Vervoort
name: ED Hawkins
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 The Authors JQ1 is a BET-bromodomain inhibitor that has immunomodulatory effects. However, the precise molecular mechanism that JQ1 targets to elicit changes in antibody production is not understood. Our results show that JQ1 induces apoptosis, reduces cell proliferation, and as a consequence, inhibits antibody-secreting cell differentiation. ChIP-sequencing reveals a selective displacement of Brd4 in response to acute JQ1 treatment (<2 h), resulting in specific transcriptional repression. After 8 h, subsequent alterations in gene expression arise as a result of the global loss of Brd4 occupancy. We demonstrate that apoptosis induced by JQ1 is solely attributed to the pro-apoptotic protein Bim (Bcl2l11). Conversely, cell-cycle regulation by JQ1 is associated with multiple Myc-associated gene targets. Our results demonstrate that JQ1 drives temporal changes in Brd4 displacement that results in a specific transcriptional profile that directly affects B cell survival and proliferation to modulate the humoral immune response.
Long-term performance of nanocomposite in power transmission and distribution systems
Creators: name: Liang, Mu
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 400805
subject: Electrical energy transmission, networks and systems
classificationCode: 401609
subject: Polymers and plastics

description: The use of nanofillers to enhance the properties of conventional composite has been studied since the 1990s. It has been proved that nanocomposite has superior mechanical, electrical and thermal properties compared with conventional composite. When polymer devices were first used in power transmission systems to replace porcelain devices, many of them did not reach the expected service life, and early failures created many challenges for the power companies. Just like most polymeric materials, the long-term performance of nanocomposite faces the same problem, an issue which demands further investigation. In this thesis, the effect of accelerated weathering on different kinds of nanocomposite, as well as micro-composite and micro-nano-composite, is studied. The specimens are prepared using various types of synthesising methods including sonication and a relatively new technique called the ‘planetary centrifugal mixing technique’. The latter technique is an effective synthesizing method that could be applied in industry to produce bulk nanocomposite with a good dispersion of nano-fillers within a host matrix. Detailed analysis and comparison between these mixing techniques to achieve a uniform dispersion of the fillers are presented. In order to simulate the long-term aging process in these specimens, a multi-stress accelerated aging method based on ASTM G154 standard is applied to age the nano, micro, and micro-nano-composite specimens. The experimental results show improvements in electrical, thermal and mechanical properties such as improved dielectric breakdown strength, glass transition temperature and thermal stability in nanocomposite and nano-micro-composite both before and after aging. All the nanocomposite specimens exhibit a significantly higher glass transition temperature than pure epoxy resin specimens; the results also showed that the accelerated aging process tends to further increase the glass transition temperature, which can be explained by the curing behaviour of epoxy resin. However, both nanocomposite and nano-micro-composite tended to lose the superior surface partial discharge resistance after the accelerated aging. The outcomes of this thesis proved that the most of the unique bulk properties of nanocomposite and nano-micro-composite can remain after a lengthy aging process, but the superior surface properties tend to degrade with time. This research also provides an effective approach for synthesising nanocomposite materials.
A coumarin derivative-Cu2+complex-based fluorescent chemosensor for detection of biothiols
Creators: name: NK Hien
name: M Van Bay
name: PD Tran
name: NT Khanh
name: ND Luyen
name: Vo, Quan Van
name: DU Van
name: PC Nam
name: DT Quang
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © The Royal Society of Chemistry. Herein, a novel fluorescent sensor has been developed for the detection of biothiols based on theoretical calculations of the stability constant of the complex between a Cu2+ ion and (E)-3-((2-(benzo[d]thiazol-2-yl)hydrazono)methyl)-7-(diethylamino) coumarin (BDC) as a fluorescent ligand. In this study, on the basis of density functional theory method, the Gibbs free energy of ligand-exchange reaction and the solvation model were carried out using thermodynamic cycles. The obtained results are in good agreement with the experimental data. The BDC-Cu2+ complex can be used as a fluorescent sensor for the detection of biothiols in the presence of non-thiol containing amino acids, with a detection limit for cysteine at 0.3 μM. Moreover, theoretical calculations of excited states were used to elucidate variations in the fluorescence properties. The computed results show that the excited doublet states D2 and D1 are dark doublet states, which quench the fluorescence of the complex.
sj-pdf-1-cpx-10.1177_21677026221137006 – Supplemental material for Detecting Impending Symptom Transitions Using Early-Warning Signals in Individuals Receiving Treatment for Depression
Creators: name: Helmich, Marieke A.
name: Smit, Arnout C.
name: Bringmann, Laura F.
name: Schreuder, Marieke J.
name: Oldehinkel, Albertine J.
name: Wichers, Marieke
name: Snippe, Evelien
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-1-cpx-10.1177_21677026221137006 for Detecting Impending Symptom Transitions Using Early-Warning Signals in Individuals Receiving Treatment for Depression by Marieke A. Helmich, Arnout C. Smit, Laura F. Bringmann, Marieke J. Schreuder, Albertine J. Oldehinkel, Marieke Wichers and Evelien Snippe in Clinical Psychological Science
The radical scavenging activity of moracins: theoretical insights
Creators: name: Vo, Quan Van
name: NT Hoa
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © The Royal Society of Chemistry. Moracins are natural products that have been isolated from different plants such as Artocarpus heterophyllus, Cassia fistula, Morus alba, and Morus mesozygia. Studies showed that moracins may have various advantageous physiological effects such as anticancer, anti-inflammatory, anticholinesterase and particularly antioxidant activities. Most of these bioactivities have not been studied systematically. In this study, the radical scavenging of a typical moracin (moracin M, MM) against HO and HOO radicals was evaluated by thermodynamic and kinetic calculations in the gas phase as well as in water and pentyl ethanoate solvents. It was found that the overall rate constants for the HO radical scavenging in the gas phase and the physiological environments are in the range of 1011 to 1010 M-1 s-1, respectively. For the HOO + MM reaction the rate constants are 4.10 × 107 and 3.80 × 104 M-1 s-1 in the polar and lipid media, respectively. It is important to notice that the single electron transfer pathway of the anion state (MM-O6′-) dominated the HOO radical scavenging in the aqueous solution, whereas in lipid medium the neutral MM exerted its activity by the formal hydrogen transfer mechanism. The HOO radical scavenging of MM is comparable to that of Trolox in lipid medium, whereas it is 315.4 times more active in the polar environment.