cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Film Sound Analysis Framework: A Conceptual tool to Interpret the Cinematic Experience
Creators: name: Barbosa, Álvaro
name: Dizon, Kristine
Publisher: name: Journal of Science and Technology of the Arts
Year: 2020

description: Today, the importance of sound and music in film is well established and an integral part of professional workflows within the audio-visual production industry. However, Sound and Music Design in film has been explored creatively since the advent of Talkies in the 1920’s. The most well-established practices for the use of sound in film always came from the inspiration of film directors, editors and composers, but in recent years the systematic use of Sound and Music in this media has become increasingly relevant in academic domains, as a subject of study and research. This article proposes a possible direction in addressing challenges presented by this growing academic field, by introducing a process for codifying and systematizing an initial grammar of Sound in Film, entitled the Film Sound Analysis Framework (FSAF). The FSAF is a tool for critical analysis of Sound and Music in Film, that is based on the relationship between Sound Semantics and Syntax from a Taxonomical and Applied perspective. Using the FSAF in longitudinal studies of film, allows for a systematic analysis by the observation of similar variables through the identification and assessment of patterns or trends, when using Sound to convey meaning and foster emotions.
description: Journal of Science and Technology of the Arts, v. 12 n. 2 (2020): Special Issue: On Cinema
Between the Screen-Sediment and the Shattered Window: The Deconstruction of the Screens Limits and Frames in Moving Image Installations
Creators: name: Branco, Sara Castelo
Publisher: name: Journal of Science and Technology of the Arts
Year: 2020

description: In the view of the continuous transformations in the structures of production, distribution and consumption of images, concepts such as expanded cinema or cinema of exhibition enlarged the spectrum of cinema to the contemporary art, which has also become a space to meditate about the fate of the cinematographic device. From a trans-historical and interdisciplinary approach – going from the pictorial perspectiva artificiallis to the pre-cinematographic instruments, cinema, and contemporary art – this paper seeks to reflect, by using the historical metaphor of the window, on the volatility and multiplicity of contemporary screens and their influence on today’s modes of vision. The paper also addresses the changes undergone in the image’s frames and the consequent paradigm shift in how the viewer physically relates with these images, summoning the work of the Portuguese artist Alexandre Estrela to consider the perceptive, cognitive and topological reconfigurations in the moving-image exhibition formats in museums and art galleries.
description: Journal of Science and Technology of the Arts, v. 12 n. 2 (2020): Special Issue: On Cinema
title:  Using transcranial magnetic stimulation to investigate the acute effects of translingual neurostimulation in individuals with Multiple Sclerosis
Creators: name: Blaney, Abby E.
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Introduction: Non-invasive neuromodulation techniques have emerged as a promising treatment to facilitate rehabilitation for individuals with Multiple Sclerosis (MS). One neuromodulation method, translingual neurostimulation (TLNS), involves electrical stimulation of the tongue and when paired with physiotherapy, is proposed to improve gait and balance in individuals with MS. Studies reporting the efficacy of TLNS for improving gait and balance in several neurological disorders are not congruent and the actual mechanisms underlying TLNS is not fully understood. Non-invasive brain stimulation devices such as transcranial magnetic stimulation (TMS) can help elucidate how TLNS may work to influence plasticity and recovery. Methods: Participants were recruited from a clinical trial in which individuals with multiple sclerosis (MS) were randomized to receive either a real or modified TLNS device. TMS variables, including resting motor threshold (RMT), active motor threshold (AMT) and recruitment curves (excitatory and inhibitory) were measured pre and post a 20-minute TLNS stimulation. Results: A repeated measures ANOVA using mixed models was conducted to investigate changes in corticospinal excitability between the TLNS stimulation and sham groups pre and post stimulation. Comparing pre and post RMT, AMT and REC values, there were no significant differences in maximum stimulator output (%MSO), motor evoked potential (MEP) amplitude latency or cortical silent period (CSP) between the stimulation and sham groups (p > 0.1). Conclusion: Our analysis of the TMS variables, RMT, AMT and recruitment curves, indicate that 20 minutes of TLNS did not increase corticospinal excitability or decrease inhibition in individuals with MS. Future research will interrogate overall brain activation through changes in cerebral blood flow.
The Invisible Woman: "Rebecca", after an audiovisual essay by R.V. Lisboa
Creators: name: Bértolo, José
Publisher: name: Journal of Science and Technology of the Arts
Year: 2020

description: This article analyzes several aesthetic, narrative and theoretical topics firstly developed by Alfred Hitchcock in Rebecca (1940) and recently explored and reinvented by Ricardo Vieira Lisboa in his audiovisual essay some visual thoughts about perception in Rebecca (2020). Other specific works and references also come into play, such as the (original and derivative) novels of Daphne du Maurier and Ana Teresa Pereira, other films by Hitchcock, and Stanley Cavell’s conceptualization of the “unknown woman” in classical melodrama. In Hitchcock’s film, the topics under analysis here are narratively acted out in the characters of Rebecca and the unnamed protagonist played by actress Joan Fontaine. However, they also materialize theoretical aspects of the spectral ontology of cinema: i.e. the dynamics between absence and presence, invisibility and visibility, past and present, the dead and the living, perception and point of view, the indexicality and materiality of moving images.
description: Journal of Science and Technology of the Arts, v. 12 n. 2 (2020): Special Issue: On Cinema
Counter-Devices of Moving Image: The Werner Nekes Collection
Creators: name: Mire, Maria
Publisher: name: Journal of Science and Technology of the Arts
Year: 2020

description: If we trace an archaeological perspective on the history of moving image, we will invariably find innumerable visual devices that both belong to the field of science and that have become popular optical toys. Allowing therefore to put in discussion if the nature of cinematic experience is in fact rooted historically in cinema, since this is a diffuse experience, synthesized in devices that wanted to give back anima to what had previously been fixed in an image. It is for this precise reason that it is particularly pertinent to approach in this context the Werner Nekes' collection of optical devices, because it possesses unique qualities as an archive that condenses the history of visual media, cross-referencing it with visual culture in its popular expression, as well as with the universe of fine arts and contemporary art.
description: Journal of Science and Technology of the Arts, v. 12 n. 2 (2020): Special Issue: On Cinema
Genetic analysis of Bactrocera zonata (Diptera: Tephritidae) populations from India based on cox1 and nad1 gene sequences
Creators: name: Jaipal S. Choudhary
name: Naiyar Naaz
name: Moanaro Lemtur
name: Das, Bikash
name: Singh, Arun Kumar
name: Bhagwati P. Bhatt
name: Prabhakar, Chandra S.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 60506 Virology

description: The peach fruit fly, Bactrocera zonata, is among the most serious and polyphagous insect pest of fruit crops in many parts of the world under genus Bactrocera. In the present study, the genetic structure, diversity and demographic history of B. zonata in India were inferred from mitochondrial cytochrome oxidase 1 (cox1) and NADH dehydrogenase 1 (nad1) sequences. The efficiency of DNA barcodes for identification of B. zonata was also tested. Genetic diversity indices [number of haplotypes (H), haplotype diversity (Hd), nucleotide diversity (π) and average number of nucleotide differences (k)] of B. zonata populations across India maintain high level of genetic diversity without isolation by distance among the geographic regions. Non-significant negative correlation between pairwise Fst and geographic distance suggests a high level of gene flow among studied populations of B. zonata. The possibility of sudden expansion of B. zonata revealed through mismatch distribution analysis as well as negative Tajima’s D and Fu’s Fs values further supported by star-like network of haplotypes. DNA barcoding analysis suggests that B. zonata specimens can be clearly differentiated from other species with 100% accuracy of identification. Therefore, cytochrome oxidase 1 (cox1) barcode sequences generated in the present study could be a valuable source for the rapid identification and global population genetic study of B. zonata.
Deep sequencing reveals the mitochondrial DNA variation landscapes of breast-to-brain metastasis blood samples
Creators: name: McGeehan, Rhiannon E.
name: Cockram, Lewis A.
name: D. Timothy J. Littlewood
name: Keatley, Kathleen
name: Eccles, Diana M.
name: An, Qian
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Breast-to-brain metastasis (BBM) often represents a terminal event, due to the inability of many systemic treatments to cross the blood–brain barrier (BBB), rendering the brain a sanctuary site for tumour cells. Identifying genetic variations that can predict the patients who will develop BBM would allow targeting of adjuvant treatments to reduce risk while disease bulk is minimal. Germ-line genetic variations may contribute to whether a BBM forms by influencing the primary tumour subtype that presents, or by influencing the host response to the tumour or treatment regimen, or by facilitating transition of tumour cells across the BBB and establish a viable brain metastasis. The role of mitochondrial DNA (mtDNA) variants specifically in BBM is underexplored. Consequently, using a sensitive deep sequencing approach, we characterized the mtDNA variation landscapes of blood samples derived from 13 females who were diagnosed with early-onset breast cancer and later went on to develop BBM. We also predicted the potential pathogenic significance of variations identified in all mtDNA-encoded oxidative phosphorylation (OXPHOS) proteins using 3D protein structural mapping and analysis, to identify variations worthy of follow-up. From the 70 variations found in protein coding regions, we reveal novel links between three specific mtDNA variations and altered OXPHOS structure and function in 23% of the BBM samples. Further studies are required to confirm the origin of mtDNA variations, and whether they correlate with (1) the predicted alterations in mitochondrial function and (2) increased risk of developing breast-to-brain metastasis using a much larger cohort of samples.
Phylogenetic studies and comparative chloroplast genome analyses elucidate the basal position of halophyte Nitraria sibirica (Nitrariaceae) in the Sapindales
Creators: name: Lu, Lu
name: Li, Xia
name: Zhaodong Hao
name: Liming Yang
name: Jingbo Zhang
name: Peng, Ye
name: Haibin Xu
name: Lu, Ye
name: Zhang, Jin
name: Jisen Shi
name: Jinhui Chen
name: Tielong Cheng
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Nitraria sibirica is a halophyte and belongs to the family Nitrariaceae. The chloroplast genome of Nitraria sibirica (159,466 bp) has a quadripartite structure, which consists of a large single-copy (87,914 bp) region, a small single-copy (18,316 bp) region, and a pair of inverted repeats (26,618 bp). Sequencing analyses indicate that the chloroplast genome contains 113 distinct genes, including 79 peptide-coding genes, 30 transfer RNA genes, and 4 ribosomal RNA genes. We also identified 105 perfect simple sequence repeats, 12 most divergent non-coding regions, and 6 most divergent coding regions when compared to the chloroplast genomes of the Sapindales plants. Phylogenetic analyses using the concatenated amino acid sequences of 58 protein-coding genes from 48 species suggest that the ‘basal’ position of Nitraria sibirica belongs to the Sapindales clade. We also found that the inverted repeat expansion resulted in a duplication of rps19 in Nitraria sibirica when comparing its chloroplast genome structure with Theobroma cacao, Vitis vinifera, Eucalyptus erythrocorys and Arabidopsis thaliana. The duplication of rps19 gene was consistent with that in Zanthoxylum piperitum, Azadirachta indica, Sapindus mukorossi and Citrus sinensis, all of which belong to the order Sapindales, but different from most Rosids plants. In summary, the analyses of Nitraria sibirica chloroplast genome not only provide insights into comparative genome analysis, but also pave the way for a better understanding of the phylogenetic relationships within the Sapindales.
Phylogenetic studies and comparative chloroplast genome analyses elucidate the basal position of halophyte Nitraria sibirica (Nitrariaceae) in the Sapindales
Creators: name: Lu, Lu
name: Li, Xia
name: Zhaodong Hao
name: Liming Yang
name: Jingbo Zhang
name: Peng, Ye
name: Haibin Xu
name: Lu, Ye
name: Zhang, Jin
name: Jisen Shi
name: Jinhui Chen
name: Tielong Cheng
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Nitraria sibirica is a halophyte and belongs to the family Nitrariaceae. The chloroplast genome of Nitraria sibirica (159,466 bp) has a quadripartite structure, which consists of a large single-copy (87,914 bp) region, a small single-copy (18,316 bp) region, and a pair of inverted repeats (26,618 bp). Sequencing analyses indicate that the chloroplast genome contains 113 distinct genes, including 79 peptide-coding genes, 30 transfer RNA genes, and 4 ribosomal RNA genes. We also identified 105 perfect simple sequence repeats, 12 most divergent non-coding regions, and 6 most divergent coding regions when compared to the chloroplast genomes of the Sapindales plants. Phylogenetic analyses using the concatenated amino acid sequences of 58 protein-coding genes from 48 species suggest that the ‘basal’ position of Nitraria sibirica belongs to the Sapindales clade. We also found that the inverted repeat expansion resulted in a duplication of rps19 in Nitraria sibirica when comparing its chloroplast genome structure with Theobroma cacao, Vitis vinifera, Eucalyptus erythrocorys and Arabidopsis thaliana. The duplication of rps19 gene was consistent with that in Zanthoxylum piperitum, Azadirachta indica, Sapindus mukorossi and Citrus sinensis, all of which belong to the order Sapindales, but different from most Rosids plants. In summary, the analyses of Nitraria sibirica chloroplast genome not only provide insights into comparative genome analysis, but also pave the way for a better understanding of the phylogenetic relationships within the Sapindales.
Research Data Management: Writing your first Data Management Plan
Creators: name: Kurapati, Shalini
Publisher: name: Zenodo
Year: 2020

description: Part 1:  Short recap of the 18 Feb session FAIR data Selection & preservation Data sharing Responsibilities & Resources
 Part 2: Set-up of dmponline Writing a dmp for an H2020 project Group discussion Feedback
title: Development of bioinformatics tools for the characterization and classification of low abundant microbes at the strain level, with a study case of SARS-CoV2
Creators: name: Vafadoost, Zahra
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Microbiome and metagenomics studies are key research areas to understand several diseases important for public health. The latest sequencing technologies have allowed affordable massive sequencing of specimen microenvironment and the characterization of pathological microbe strains. Strain level is the lowest level of taxonomic ranks; the characterization of strain sequences of a pathological microbe helps track new potential virulent variants and vaccine development. My master project aimed to; 1) set a bioinformatics pipeline for specimen metagenomics analysis; and 2) characterize potential bias linked to sequencer technologies. A publicly available dataset of human tissues and SARS-CoV-2 swab specimens from the Global Initiative on Sharing All Influenza Data (GISAID)[1] database was used. In detail, a pipeline was designed to analyze low-abundance metagenomics sequencing data from RNA samples extracted from human tissues. Furthermore, taking advantage of the worldwide effort to track the emergence of SARS-CoV-2 variants, sequencing datasets gathered via the two main sequencing platforms (Illumina and Nanopore) were analyzed to identify potential sequencing biases linked to specific sequencing protocols. Also, a descriptive analysis was generated by applying clustering techniques to the phylogenetic tree and processing and evaluating the metadata's effect on the dataset. Overall, my project guides analyzing metagenomics data for strain characterization when working with low-abundant microbiome data.
Teacher Model Fingerprinting Attacks Against Transfer Learning
Creators: name: Chen, Yufei
name: Shen, Chao
name: Wang, Cong
name: Zhang, Yang
Publisher: name: CISPA
Year: 2023

description: Transfer learning has become a common solution to address
training data scarcity in practice. It trains a specified student model by reusing or fine-tuning early layers of a well-trained teacher model that is usually publicly available. However, besides utility improvement, the transferred public knowledge also brings potential threats to model confidentiality, and even further raises other security and privacy issues.

In this paper, we present the first comprehensive investigation of the teacher model exposure threat in the transfer learning context, aiming to gain a deeper insight into the tension between public knowledge and model confidentiality. To this end, we propose a teacher model fingerprinting attack to infer the origin of a student model, i.e., the teacher model it transfers from. Specifically, we propose a novel optimizationbased method to carefully generate queries to probe the student model to realize our attack. Unlike existing model reverse engineering approaches, our proposed fingerprinting method neither relies on fine-grained model outputs, e.g., posteriors, nor auxiliary information of the model architecture or training dataset. We systematically evaluate the effectiveness of our proposed attack. The empirical results demonstrate that our attack can accurately identify the model origin with few probing queries. Moreover, we show that the proposed attack can serve as a stepping stone to facilitating other attacks against machine learning models, such as model stealing.
Additional file 1: of Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016
Creators: name: Liu, Weiping
name: Liu, Jiangmei
name: Song, Yuqin
name: Zeng, Xinying
name: Wang, Xiaopei
name: Mi, Lan
name: Cai, Cai
name: Wang, Lijun
name: Ma, Jun
name: Zhu, Jun
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Hematology

description: Table S1. Age-standardized incidence rates of lymphoma by age and sex in 2016 (per 100,000). Table S2. Age-standardized mortality rates of lymphoma by age and sex in 2016 (per 100,000). Table S3. Age-standardized incidence, mortality and prevalence rates of lymphoma by province of China in 2016 (per 100,000). Figure S1. Relation between lymphoma burden and socio-demographic index (SDI) at provincial level (A) age-standardized incidence rate (ASIR) of Hodgkin lymphoma (HL) vs. SDI, (B) age-standardized mortality rate (ASMR) of HL vs. SDI, (C) age-standardized prevalence rate (ASPR) of HL vs. SDI, (D) age-standardized disability-adjusted life years (DALYs) of HL vs. SDI, (E) ASIR of non-Hodgkin lymphoma (NHL) vs. SDI, (F) ASMR of NHL vs. SDI, (G) ASPR of NHL vs. SDI, (H) age-standardized DALYs of NHL vs. SDI. (PDF 687 kb)
Model-based Motion Estimation of Elastic Surfaces for Minimally Invasive Cardiac Surgery
Creators: name: Bader, Thomas
name: Wiedemann, Alexander
name: Roberts, Kathrin
name: Hanebeck, Uwe D.
Publisher: name: Karlsruhe
Year: 2007

description: In order to assist surgeons during surgery on moving organs, e.g. minimally invasive beating heart bypass surgery, a master-slave system which synchronizes surgical instruments with the organ's motion is desired. This synchronization requires reliable estimation of the organ's motion. In this paper, we present a new approach to motion estimation based on a state motion model for a partition of the heart's surface. Its motion behavior is described by a partial differential equation whose input function is assumed to be periodic. An estimator is used on one hand to predict future model states based on reconstruction of the input function and on the other hand to incorporate noisy spatially discrete measurements in order to improve state estimation. The model-based motion estimation is evaluated using a simple heart simulator. Measurements are obtained by reconstructing 3D position of markers on a pulsating membrane by means of a stereo camera system.
Synthesis and evaluation of antimicrobial properties of new Mannich bases of 4,5-disubstituted-1,2,4-triazole-3-thiones
Creators: name: Łukasz Popiołek
name: Biernasiuk, Anna
name: Paruch, Kinga
name: Paweł Patrejko
name: Wujec, Monika
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: This study presents the synthesis and antimicrobial properties of new Mannich bases of 1,2,4-triazole-3-thiones. New compounds were prepared by the reaction of 4,5-disubstituted-1,2,4-triazole-3-thiones with formaldehyde and various amines. The structures of the prepared compounds were established on the basis of spectral methods (1H NMR, 13C NMR). All synthesized compounds were tested for in vitro antimicrobial activity by broth microdilution method using the reference Gram-positive and Gram-negative bacterial strains and fungi belonging to Candida spp. Antimicrobial assays revealed that newly synthesized compounds: 8, 9, 10, 15, and 17 showed some antimicrobial activity against reference Gram-positive bacteria or yeasts with good to moderate activity of 9 and 15 towards B. subtilisATCC 6633.
Indirect comparison of bronchial thermoplasty versus omalizumab for uncontrolled severe asthma
Creators: name: Niven, Robert M.
name: Simmonds, Michael R.
name: Cangelosi, Michael J.
name: Tilden, Dominic P.
name: Cottrell, Suzanne
name: Shargill, Narinder S.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: Objective: Bronchial thermoplasty (BT) as an add-on therapy for uncontrolled severe asthma is an alternative to biologic therapies like omalizumab (OM). We conducted an indirect treatment comparison (ITC) to appraise comparative effectiveness of BT and OM. Methods: A systematic literature review identified relevant randomized controlled trials. The ITC followed accepted methodology. Results: The ITC comprised a sham-controlled trial of BT (AIR2) and two placebo-controlled trials of OM (INNOVATE; EXTRA). Comparing the BT post-treatment period to ongoing treatment with OM, showed no significant differences in the rate ratios (RRs) for severe exacerbations (RR of BT versus OM = 0.91 [95% CI: 0.64, 1.30]; p = 0.62) or hospitalizations (RR = 0.57 [95% CI: 0.17, 1.86]; p = 0.53); emergency department visits were significantly reduced by 75% with BT (RR = 0.25 [95% CI: 0.07, 0.91]; p = 0.04); the proportions of patients with clinically meaningful response on the asthma quality-of-life questionnaire were comparable (RR = 1.06 [95% CI: 0.86, 1.34]; p = 0.59). The RR for exacerbations statistically favours OM over the total study period in AIR2 (RR = 1.50 [95% CI: 1.11, 2.02]; p = 0.009) likely reflecting a transient increase in events during the BT peri-treatment period. Conclusions: The ITC should be interpreted cautiously considering the differences between patient populations in the included trials. However, based on the analysis, BT compares well with a potentially more costly pharmacotherapy for asthma. Clinicians evaluating the relative merits of using these treatments should consider the totality of evidence and patient preferences to make an informed decision.
Earthworm extract as a biocatalyst for asymmetric Mannich addition of cyclic ketimine 3-aryl-2H-1,4-benzoxazines
Creators: name: Wu, Ling-Ling
name: Zeng, Qing-Qing
name: Ya-Xuan Yang
name: Hu, Hong-Feng
name: Guan, Zhi
name: He, Yan-Hong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: The asymmetric Mannich reaction of 3-substituted-2H-1,4-benzoxazines and acetone catalysed by a crude extract from earthworms is reported. The influence of solvents, water contents, catalyst loading, amounts of substrates and temperature on the reaction was investigated. Yields of up to 51% with enantioselectivities of up to 87% ee were achieved under the optimized conditions. This research promotes the development of earthworm extract as a catalyst in Mannich reaction.
title: Lineamientos Centro de Recursos para el Aprendizaje y la Investigación (CRAI)
Creators: name: Universidad del Rosario. CRAI
Publisher: name: Universidad del Rosario
Year: 2022

description: El documento tiene como objetivo establecer los Lineamientos del Centro de Recursos para el Aprendizaje y la Investigación (CRAI) de la Universidad del Rosario a partir del análisis de las principales tendencias internacionales que afectan a las bibliotecas académicas, señalando las implicaciones que tienen para las Instituciones de Educación Superior y el camino que deben recorrer para innovar en los servicios de soporte al aprendizaje, la investigación y la extensión. Para la Universidad del Rosario, el documento de lineamientos del CRAI es el fruto de los avances de transformación de la biblioteca como área transversal de soporte de quehacer universitario, realizados por nuestra institución en su apuesta por la innovación. El documento aborda, desde el análisis de tendencias, el rol y la importancia de los servicios de soporte a la academia, la investigación y la extensión.
ECG markers associated with ischemic stroke at young age – a case-control study
Creators: name: Pirinen, Jani
name: Eranti, Antti
name: Knekt, Paul
name: Lehto, Mika
name: Martinez-Majander, Nicolas
name: Aro, Aapo L.
name: Rissanen, Harri
name: Heliövaara, Markku
name: Kaste, Markku
name: Tatlisumak, Turgut
name: Huikuri, Heikki
name: Putaala, Jukka
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Introduction: Certain electrocardiographic (ECG) abnormalities are associated with ischemic stroke (IS), especially cardioembolic subtype. Besides atrial fibrillation, markers of left ventricular hypertrophy (LVH) or atrial pathology also reflect elevated risk. We studied the association of ECG markers with IS in young adults. Methods: We performed a case-control study including 567 consecutive IS patients aged 15–49 years (inclusion period: 1994–2007) and one or two age- and sex-matched control subjects enrolled during 1978–1980 (n = 1033), and investigated also the stroke aetiologic subgroups. We studied ECGs of all participants for markers of atrial abnormality, i.e. P-terminal force (PTF) on lead V1, interatrial blocks (IAB; P-wave duration ≥110 ms), and LVH. Conditional logistic regression analyses were used. Results: IAB (hazard ratio [HR]: 1.57, 95% confidence interval [CI]: 1.16–2.13) and PTF combined with LVH (HR: 6.83, 95% CI: 1.65–28.31), were independently associated with IS. LVH, abnormal P-wave (HR: 6.87, 95% CI: 1.97–135.29), PTF, IAB, and combinations of these P-wave abnormalities with LVH – were associated with cardioembolic subtype. Abnormal P-wave and IAB were associated with cryptogenic stroke subtype. In unadjusted analysis, LVH was associated with small-vessel disease subtype. Conclusion: P-wave abnormalities on ECG were associated with cardioembolic but also with a cryptogenic subtype of IS.Key messagesECG patterns associated with atrial pathology are markers of increased risk of ischemic stroke in young adults.The ECG markers reflecting atrial pathology were seen in patients with cardioembolic and cryptogenic subtypes of ischemic stroke. ECG patterns associated with atrial pathology are markers of increased risk of ischemic stroke in young adults. The ECG markers reflecting atrial pathology were seen in patients with cardioembolic and cryptogenic subtypes of ischemic stroke.
Online Resources/Supplementary Materials for the Article: Comparison of Adverse Events in Pregnant Persons receiving COVID-19 and Influenza Vaccines: A Disproportionality Analysis using Combined Data from US VAERS and Eudravigilance spontaneous report databases
Creators: name: Roque-Pereira, Leonardo
Publisher: name: Zenodo
Year: 2025

description: Supplementary Material Caption:

ESM_1/Online Resource 1: Common Data Model to map VAERS and EV variables

ESM_2/Online Resource 2: The READUS-PV checklist to enhance transparency, completeness and accuracy on the reporting of disproportionality analyses conducted using ICSR databases20

ESM 3/Online Resource 3: Frequency of pregnancy-ICSRs per country

ESM 4/Online Resource 4: Most reported Maternal and Neonatal Outcome-High-level with complete list of PTs

ESM 5/Online Resource 5: sensitivity analyses in VAERS and EV

ESM_6/Online Resource 6: Key variables of SDRs for case-by-case analysis

ESM_7/Online Resource 7: PRR estimates pr each HLT-vaccine combination

 

Comparison of Adverse Events in Pregnant Persons receiving COVID-19 and Influenza Vaccines: A Disproportionality Analysis using Combined Data from US VAERS and Eudravigilance spontaneous report databases

 

Drug Safety Journal

 

Authors:

Leonardo Roque-Pereira (0000-0002-5878-5088)1, Malede Mequanent Sisay1, Comfort K. Ogar2, Carlos E. Durán1(0000-0003-1853-3641), Eugene Van Puijenbroek3,5, Daniel Weibel1, Katia Verhamme4 , Miriam Sturkenboom1

 

Affiliation:

1 Department of Data Science and Biostatistics, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands

 2 Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands

3 University of Groningen, Groningen Research Institute of Pharmacy, PharmacoTherapy, - Epidemiology & -Economics, The Netherlands

4Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands

5Pharmacovigilance centre Lareb, 's-Hertogenbosch, the Netherlands
Biodiversity Measures to Summarize Antibiotic Resistance
Creators: name: Sovit Chalise
name: Hurford, Amy
name: Jianhong Wu
name: Hughes, Josie
name: Morris, Andrew M.
Publisher: name: figshare
Year: 2019
Subjects: Computational Biology

description: R script for data analysis in the manuscript Biodiversity Measures to Summarize Antibiotic Resistance. The data set included here is an example data set as the original data set cannot be made available without request to the Public Health Agency of Canada. Hence the R script will run but will create different figures and give different statistical results compared to the original figure and results in the manuscript.
Please use R version (3.3.2; 2016-10-31).
The combined effect of Macondo oil and corexit on sheepshead minnow (Cyprinodon variegatus) during early development
Creators: name: Bosker, Thijs
name: Balen, Liselotte Van
name: Brid Walsh
name: Sepúlveda, Marisol S.
name: DeGuise, Sylvain
name: Perkins, Chris
name: Griffitt, Robert J.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: During the 2010 Deepwater Horizon (DWH), oil spill an estimated 800 million L oil and 7.9 million L dispersant entered the environment. The potential adverse effects of the oil-dispersant mixture are poorly understood. The aim of this study was to investigate the impacts of this mixture on early development of sheepshead minnow (Cyprinodon variegatus), a small-bodied estuarine fish commonly found in the area affected by the DWH spill. Embryos were exposed to a chemically enhanced water accommodated fraction (CEWAF; 10:1 mixture of Macondo oil; Corexit 9500) for 48 hr, after which organisms were maintained in uncontaminated water for an additional 8 days. Impacts were assessed on embryonic (heart rate, development of eye pigmentation, embryonic movement measured) and larval (time to hatch, larval survival, standard length, and cyp1a gene expression) development. No significant alterations were found in survival, time to hatch or cyp1a at the end of the experiment. However, CEWAF induced significant decreases in heart rate of embryos, delayed development of eye pigmentation, reduced embryonic movement, and diminished standard length. These results indicate potential sublethal adverse consequences attributed to CEWAF exposure during early development, even in the absence of maintained cyp1a induction or survival rate, potentially affecting the fitness of organisms later in life.
title: The impact of migration on status within the informal political conversation
Creators: name: Urrego Guzman, Natalia
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2023

description: Migrants' lives are rarely strongly divided between their home and host countries. Instead, their lives orbit between two or sometimes more countries, becoming generators of cross border exchanges with simultaneous loyalties and political participation in several countries. The informal transnational political conversation is a reflection of the overlapping political rights and practices that are forged and maintained through migration. This thesis examines the impact of migration on status within the informal transnational political conversation. It presents findings regarding the effects of migration on political interest and on homogeneity in the characteristics of political conversation partners the importance of perception in political expertise and political ideology as an element in maintaining trustworthiness within the transnational conversation. It is concluded that migration affects not only the political conversation from the point of view of internal dynamics of influence but also impacts the conversation participants themselves , in terms of their characteristics and interests . The thesis also presents a possible avenue for future research.
Electrochemical Determination of 6-Thioguanine and Its Interaction with DNA Oligonucleotides Using Disposable Graphite Pencil Electrodes
Creators: name: Unal, Didem Nur
name: Eksin, Ece
name: Arzum Erdem
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Disposable graphite pencil electrodes were used in this study for the electrochemical determination of 6-thioguanine using its interaction with a single-stranded Oligo (A)25 composed of 25 adenine (A) bases or double-stranded Oligo (A)25–Oligo (T)25, a hybrid form of Oligo (A)25 and Oligo (T)25 composed of 25 thymine (T) bases. The surface interaction was evaluated by monitoring the changes of the oxidation signals of 6-thioguanine and adenine. The electrochemical measurements were performed using differential pulse voltammetry, cyclic voltammetry, and electrochemical impedance spectroscopy. The experimental conditions, including the concentration of 6-thioguanine and its period of interaction with single-stranded Oligo (A)25 or double-stranded Oligo (A)25–Oligo (T)25, were optimized by observing the changes in the 6-thioguanine and adenine oxidation currents by differential pulse voltammetry. The detection limit was determined to be 0.24 µM across the useful linear concentration range from 1 to 4 µM 6-thioguanine. The reported single-use graphite sensor provides a cost-effective, rapid, and sensitive detection approach for the electrochemical characterization of the interaction between DNA and 6-thioguanine.
On the Privacy Risks of Cell-Based NAS Architectures
Creators: name: Huang, Hai
name: Zhang, Zhikun
name: Shen, Yun
name: Backes, Michael
name: Li, Qi
name: Zhang, Yang
Publisher: name: CISPA
Year: 2023

description: Existing studies on neural architecture search (NAS) mainly focus on efficiently and effectively searching for network architectures with better performance. Little progress has been made to systematically understand if the NAS-searched architectures are robust to privacy attacks while abundant work has already shown that human-designed architectures are prone to privacy attacks. In this paper, we fill this gap and systematically measure the privacy risks of NAS architectures. Leveraging the insights from our measurement study, we further explore the cell patterns of cell-based NAS architectures and evaluate how the cell patterns affect the privacy risks of NAS-searched architectures. Through extensive experiments, we shed light on how to design robust NAS architectures against privacy attacks, and also offer a general methodology to understand the hidden correlation between the NAS-searched architectures and other privacy risks.
DataSet_Figures 3-4-5.zip
Creators: name: Peters, Luke
name: Tunesi, Jacob
name: Pasquazi, Alessia
name: Peccianti, Marco
Publisher: name: figshare
Year: 2017
Subjects: subject: Applied Physics
subject: 20503 Nonlinear Optics and Spectroscopy
subject: FOS: Physical sciences

description: This is the complete DataSet of an accepted publication,

The DataSet will be accessible upon paper publication.

The Link to the publication will be published when available.

In particular the file contains 3 folders which identify the original source data of Figure 3, Figure 4 and Figure 5

The format of the raw data is .mat - MATLAB binary -v7, which is compatible and portable to GNU Octave version >4.0 (tested)

Descriptors of all the variables defined in the .mat files are contained in the files

Figure3_MetaData.txt
Figure4_MetaData.txt
Figure5_MetaData.txt

The format of the raw data is .mat - MATLAB binary -v7, which is compatible and portable to GNU Octave version >4.0 (tested)

Note that for the Figure 5 data, the "screening pump" and the "generation pump powers" are both contained in the filename
e.g. "Figure5_0.2W_Pump_1.638W.mat"
MOESM1 of Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition
Creators: name: Fan, Rebecca
name: Guo, Min
name: Luo, Shouqing
name: Cui, Mei
name: Tieu, Kim
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Figure S1. Expression of tyrosine hydroxylase in N27 cells. Figure S2. Comparison of GFP signal in HeLa cells with or without PFA fixation. Figure S3. Generation of inducible expression of human α-synuclein in rat dopaminergic N27 neuronal cells. Figure S4. Efficiency of Drp1 siRNA. Figure S5 Drp1 inhibition attenuates p62 accumulation in N27 neuronal cells with inducible α-syn. Figure S6 Morphology of PFF. Table S1. Primary antibodies and dilutions used in western blot. Table S2. Primary antibodies and dilutions used in immunostaining.
Modern problems of regional transport infrastructure in russia/Aktuelle probleme der regionalen verkehrsinfrastruktur in russland
Creators: name: Kudryashov, Alexander
Publisher: name: figshare
Year: 2017
Subjects: subject: 160505 Economic Development Policy
subject: FOS: Political science
subject: 160401 Economic Geography
subject: FOS: Social and economic geography
subject: 160507 Environment Policy
subject: 160605 Environmental Politics

description: Verkehrsinfrastruktur bietet nicht nur die Einheit des Wirtschaftsraums Russlands, sondern auch einer der wichtigsten Sektoren der Wirtschaft. Nachhaltiges Wirtschaftswachstum von Regionen, die Lebensqualitä zu verbessern, ist unmöglich ohne eine ausgewogene allseitige Entwicklung des Transportkomplexes. Die räumliche Verteilung der Verkehrsinfrastruktur erhöht sich die synergistische Wirkung von mehrdimensionalen Faktoren das regionale Wirtschaftswachstum zu beeinträchtigen. Mehrere Forscher beachten: «Fahrzeuge, Transport und wirtschaftliche Beziehungen in der Regionalen Wirtschaft spezielles Funktionsstattfinden, die zentralen Konzepte direkt verknüpft wie территориальная Teilung und Integration der Arbeits, wirtschaftliche Regionalisierung, die centrale Struktur der Wirtschaft, Spezialisierung und integrierte Entwicklung der Wirtschaftsregionen. Mit anderen Worten, der Transport und Verkehr - Wirtschaftsbeziehungen - ist ein untrennbarer. Системы управления и контроля ».1 Akutes Problem der Verkehrsinfrastruktur der Region und das Land als Ganzes - ist der Zustand der Straßen und Straßeneinrichtungen. Der bestehende Transportkomplex der zentralen Regionen und Großstädte erleben konstante Spitzenlasten auf des bestehenden Straßennetz und speichert das Задача der Zugänglichkeit der Verkehrsverbindungen der Bevölkerung abgelegener Regionen. Die Analyze der statistischen Daten kann gefolgert werden, dass die Dichte der Straßen Erhöhung eine Verringerung des Anteils der Straßen sind gepflastert ist.
Neural correlates of visual memory in patients with diffuse axonal injury
Creators: name: Lauer, Juliane
name: Moreno-López, Laura
name: Manktelow, Anne
name: Carroll, Ellen L.
name: Outtrim, Joanne G.
name: Coles, Jonathan P.
name: Newcombe, Virginia F.
name: Sahakian, Barbara J.
name: Menon, David K.
name: Stamatakis, Emmanuel A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Primary objective: To investigate the neural substrates of visual memory in a sample of patients with traumatic brain injury (TBI). We hypothesized that patients with decreased grey and white matter volume in frontal and parietal cortices as well as medial temporal and occipital lobes would perform poorly on the tests of visual memory analysed. Methods and procedures: 39 patients and 53 controls were assessed on tests of visual memory and learning from the Cambridge Neuropsychological Test Automated Battery (CANTAB). Patients with TBI were scanned with magnetic resonance imaging (MRI). Partial correlations and multiple regression analyses were used to examine relationships between cognitive variables and MRI volumetric findings. This study complements and extends previous studies by performing volumetric comparisons on a variety of resolution levels, from whole brain to voxel-based level analysis. Main outcomes and results: Patients with TBI performed significantly worse than controls in all the tasks assessed. Performance was associated with wide-spread reductions in grey and white matter volume of several cortical and subcortical structures as well as with cerebrospinal fluid space enlargement in accordance with previous studies of memory in patients with TBI and cognitive models suggesting that memory problems involve the alteration of multiple systems. Conclusions: Our results propose that compromised visual memory in patients with TBI is related to a distributed pattern of volume loss in regions mediating memory and attentional processing.