cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Key Role of Reactive Oxygen Species (ROS) in Indirubin Derivative-Induced Cell Death in Cutaneous T-Cell Lymphoma Cells
Creators: name: Soltan, Marwa Y.
name: Sumarni, Uly
name: Assaf, Chalid
name: Langer, Peter
name: Reidel, Ulrich
name: Eberle, Jürgen
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: CTCL
subject: apoptosis
subject: cell viability
subject: c-FLIP
subject: XIAP
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Cutaneous T-cell lymphoma (CTCL) may develop a highly malignant phenotype in its late phase, and patients may profit from innovative therapies. The plant extract indirubin and its chemical derivatives represent new and promising antitumor strategies. This first report on the effects of an indirubin derivative in CTCL cells shows a strong decrease of cell proliferation and cell viability as well as an induction of apoptosis, suggesting indirubin derivatives for therapy of CTCL. As concerning the mode of activity, the indirubin derivative DKP-071 activated the extrinsic apoptosis cascade via caspase-8 and caspase-3 through downregulation of the caspase antagonistic proteins c-FLIP and XIAP. Importantly, a strong increase of reactive oxygen species (ROS) was observed as an immediate early effect in response to DKP-071 treatment. The use of antioxidative pre-treatment proved the decisive role of ROS, which turned out upstream of all other proapoptotic effects monitored. Thus, reactive oxygen species appear as a highly active proapoptotic pathway in CTCL, which may be promising for therapeutic intervention. This pathway can be efficiently activated by an indirubin derivative.
Stinging risk and sting pain of the ivy bee, Colletes hederae
Creators: name: Hennessy, Georgia
name: Balfour, Nicholas J.
name: Shackleton, Kyle
name: Goulson, Dave
name: Ratnieks, Francis L. W.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The ivy bee, Colletes hederae, was first detected in Britain in 2001 and is abundant in many locations. Their ground nesting aggregations can occur in public areas and cause concern about stinging risk. Here we assess that risk. The likelihood of being stung or collided with when in an active aggregation was low, with only 1 sting in 10 h of activity (standing, walking, and “gardening”) by a human subject. Collisions were low at 6 per hour. The ivy bee sting is frequently unable to penetrate human skin. Only half were able to sting the fingertips and 75% the inner forearm when held against these areas. Pain was scored using a modified Starr/Schmidt scale. Ivy bee stings were significantly less painful than those of honey bee workers Apis mellifera, with similar scores to a nettle sting, Urtica dioica. Pain subsided after 10 min with weals smaller than both honey bees and nettles. The ivy bee venom sac was ca. 39% the volume of that of a worker honey bee. The sting is similar in size to the honey bee sting and barbs were not seen at 35× magnification. We conclude that the ivy bee is not a danger to the public. They rarely sting people active in a nest aggregation area, have a sting that is frequently unable to penetrate human skin and that causes minimal pain for a short duration, comparable to that of a nettle sting. Nettle stings are considered to be annoying but not dangerous.
Teisei zōyaku Sairan igen. Kan no 2
訂正増譯采覧異言.巻之二
Creators: name: Yamamura, Masanaga.
Publisher: name: [place of publication unknown : publisher not identified]
Year: 2021

description: Cover title: 増譯采覧異言 Zōyaku Sairan igen (Enlarged Sairan igen); 采覧異言 Sairan igen is a geographical work by 新井白石 Arai Hakuseki in 1713. The 14 volumes include a preface volume, 12 volumes of text, and a volume of maps. The maps are coloured with the exception of the last four, which have only the boundaries outlined in red. All the maps occupy two facing pages, with one exception (Beans 1803.9) [East Indies]. Contents: (Beans 1803.1) 歐羅巴洲與地圖 Yōroppashū yochizu (General map of Europe); (Beans 1803.2) Horutogaru Isuhania Furansu Itaria Serumania Aran Heruheshia Suuyusserurando ijō nanakoku no zu (Map of the seven countries Portugal, Spain, France, Italy, Germany, Holland, and Switzerland); (Beans 1803.3) Teemaruka Noruweshiakoku Shueshiakoku ijō nikoku no zu [and] Koroodo Buritaniakoku no zu (Scandinavia [and] British Isles); (Beans 1803.4) [Balkans, Black Sea region and Asia Minor]; (Beans 1803.5) [Southern Russia and Poland]; (Beans 1803.6) 亞細亞洲與地圖 Ajiashū yochizu (General map of Asia); (Beans 1803.7) [East Asia]; (Beans 1803.8) [Southern Asia]; (Beans 1803.9) [East Indies]; (Beans 1803.10) 亞弗利加洲與地圖 Afurikashū yochizu (General map of Africa); (Beans 1803.11) 南亞墨利加洲與地圖 Minami Amerikashū yochizu (General map of South America); (Beans 1803.12) 北亞墨利加洲與地圖 Kita Amerikashū yochizu (General map of North America). Cited in: WSN; 125
A U-Net Deep Learning Framework for High Performance Vessel Segmentation in Patients With Cerebrovascular Disease
Creators: name: Livne, Michelle
name: Rieger, Jana
name: Aydin, Orhun Utku
name: Taha, Abdel Aziz
name: Akay, Ela Marie
name: Kossen, Tabea
name: Sobesky, Jan
name: Kelleher, John D.
name: Hildebrand, Kristian
name: Frey, Dietmar
name: Madai, Vince I.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: cerebrovascular disease
subject: deep learning
subject: medical imaging
subject: segmentation
subject: U-net
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Brain vessel status is a promising biomarker for better prevention and treatment in cerebrovascular disease. However, classic rule-based vessel segmentation algorithms need to be hand-crafted and are insufficiently validated. A specialized deep learning method-the U-net -is a promising alternative. Using labeled data from 66 patients with cerebrovascular disease, the U-net framework was optimized and evaluated with three metrics: Dice coefficient, 95% Hausdorff distance (95HD) and average Hausdorff distance (AVD). The model performance was compared with the traditional segmentation method of graph-cuts. Training and reconstruction was performed using 2D patches. A full and a reduced architecture with less parameters were trained. We performed both quantitative and qualitative analyses. The U-net models yielded high performance for both the full and the reduced architecture: A Dice value of similar to 0.88, a 95HD of similar to 47 voxels and an AVD of similar to 0.4 voxels. The visual analysis revealed excellent performance in large vessels and sufficient performance in small vessels. Pathologies like cortical laminar necrosis and a rete mirabile led to limited segmentation performance in few patients. The U-net outperfomed the traditional graph-cuts method (Dice similar to 0.76, 95HD similar to 59, AVD similar to 1.97). Our work highly encourages the development of clinically applicable segmentation tools based on deep learning. Future works should focus on improved segmentation of small vessels and methodologies to deal with specific pathologies.
On the Importance of Building High-quality Training Datasets for Neural Code Search
Creators: name: Sun, Zhensu
name: Li, Li
name: Liu, Yan
name: Du, Xiaoning
name: Li, Li
Publisher: name: Zenodo
Year: 2022

description: In our paper "On the Importance of Building High-quality Training Datasets for Neural Code Search", we propose a data cleaning framework for the training datasets of neural code search models. The implementation of this framework is a third-party Python library, Natural Language Query Filter (NLQF). NLQF is designed to filter out the noisy data given a set of comment-code pairs based on the syntax and semantic of the comments. We would like to apply for the Reusable badge and Available badge for NLQF. The evaluation of this artifact requires Python programming skills and a GPU-enabled evironment.
Open Strings on AdS_2 Branes
Creators: name: Lee, Peter
name: Ooguri, Hirosi
name: Park, Jongwon
name: Tannenhauser, Jonathan
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the spectrum of open strings on AdS_2 branes in AdS_3 in an NS-NS background, using the SL(2,R) WZW model. When the brane carries no fundamental string charge, the open string spectrum is the holomorphic square root of the spectrum of closed strings in AdS_3. It contains short and long strings, and is invariant under spectral flow. When the brane carries fundamental string charge, the open string spectrum again contains short and long strings in all winding sectors. However, branes with fundamental string charge break half the spectral flow symmetry. This has different implications for short and long strings. As the fundamental string charge increases, the brane approaches the boundary of AdS_3. In this limit, the induced electric field on the worldvolume reaches its critical value, producing noncommutative open string theory on AdS_2.
description: 51 pages, 8 figures; v2: references added, typos corrected
Reasoning about Tendency: What Does Hughes v The Queen Really Tell Us?
Creators: name: Robinson, Peter M
Publisher: name: Monash University
Year: 2019
Subjects: subject: Law
subject: FOS: Law

description: Patterns of illicit sexual misconduct by celebrities and institutional carers have been the subject of constant publicity in recent times. These episodes have often led to calls for reform of the law relating to the admission of prior conduct and convictions as evidence of criminal offences. The case of the Hey Dad..! star, Robert Hughes, triggered a High Court appeal on the subject aimed at resolving legal controversies in this area, but the High Court’s decision was regarded as insufficient by the recently completed Royal Commission Into Institutional Responses to Child Sexual Abuse, which recommended its own reform. This article argues that the problems lie in factual reasoning rather than legal rule-making. It explores the factual reasoning underlying decisions of admissibility of tendency evidence to try to shed light on issues of probative value not only under the Uniform Evidence Acts but under any legislative or common law regime.
Cardiac 123I-MIBG Scintigraphy in Neurodegenerative Parkinson Syndromes: Performance and Pitfalls in Clinical Practice
Creators: name: Skowronek, Cornelia
name: Zange, Leonora
name: Lipp, Axel
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Parkinson's disease
subject: Lewy body disorders
subject: multiple system atrophy
subject: MIBG scintigraphy
subject: autonomic function
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Purpose: Cardiac [I-123]metaiodobenzylguanidine scintigraphy (123I-MIBG), reflecting postganglionic cardiac autonomic denervation, is proposed for early detection of Parkinson's disease (PD; reduced tracer uptake) and separation from Multiple System Atrophy (MSA; preserved tracer uptake). However, several recent studies report on frequent unexpected 123I-MIBG results in PD and MSA. We sought to determine, whether 123I-MIBG is feasible to discriminate PD from MSA in unselected geriatric patients in clinical practice. Materials and Methods: We screened consecutive patients, that underwent 123I-MIBG for diagnostic reasons. Delayed 123I-MIBG uptake (heartimediastinum ratio; H/M ratio) was verified by clinical diagnosis of PD, MSA, and ET based on a two-stage clinical assessment: comprehensive baseline (including autonomic testing and additional neuroimaging) and confirmatory clinical follow-up. Results: 28 patients with clinical diagnosis of PD (N = 11), MSA (N = 9), and Essential Tremor (ET, N = 8) were identified. In one third (9/28) nuclear medical diagnosis deviated from clinically suspected syndrome. Visual interpretation of 123I-MIBG identified two cases (MSA and El) with indeed normal 123I-MIBG uptake. Detailed review of clinical phenotypes provided only in two cases (PD and ET) an adequate explanation (correction of initial diagnosis and confounding drug history) for unexpected 123I-MIBG. In conclusion, 123I-MIBG did not match initial clinical phenotype in 27% PD, 44% MSA, and 25% ET patients. Conclusion: 123I-MIBG scintigraphy is a known specific and valuable technique in scientific approaches and well-defined and highly selected samples. However, predictability of 123I-MIBG based nuclear medical diagnosis for individual cases and thus, feasibility in routine clinical practice is limited. Our clinical series emphasize clinical verification of 123I-MIBG results on an individual basis in clinical routine.
Isothermal Microcalorimetry Detects the Presence of Persister Cells in a Staphylococcus aureus Biofilm After Vancomycin Treatment
Creators: name: Butini, Maria Eugenia
name: Abbandonato, Gerardo
name: Di Rienzo, Carmine
name: Trampuz, Andrej
name: Di Luca, Mariagrazia
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Staphylococcus aureus
subject: biofilm
subject: persister cells
subject: antibiotic activity
subject: isothermal microcalorimetry
subject: vancomycin
subject: biofilm-associated infection
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Staphylococcus aureus biofilm plays a major role in implant-associated infections. Here, the susceptibility of biofilm S. aureus to daptomycin, fosfomycin, vancomycin, trimethoprim/sulfamethoxazole, linezolid, and rifampicin was investigated by isothermal microcalorimetry (IMC). Moreover, the persister status of cells isolated from S. aureus biofilm after treatment with vancomycin was also analyzed. S. aureus biofilm was tolerant to all the antibiotics tested [minimum biofilm bactericidal concentration (MBBC) 7> 256 mu g/ml], except to daptomycin [MBBC and minimum biofilm eradicating concentration (MBEC) = 32 mu g/ml] and rifampin (MBBC and MBEC = 128 mu g/ml). After the treatment of MRSA biofilm with 1024 mu g/ml vancomycin, similar to 5% cells survived, although metabolically inactive (persisters). Interestingly, IMC revealed that persister bacteria reverted to a normal-growing phenotype when inoculated into fresh medium without antibiotics. A staggered treatment of MRSA biofilm with vancomycin to kill all the metabolically active cells and daptomycin to kill persister cells eradicated the whole bacterial population. These results support the use in the clinical practice of a therapeutic regimen based on the use of two antibiotics to kill persister cells and eradicate MRSA biofilms. IMC represents a suitable technique to characterize in real-time the reversion from persister to metabolically-active cells.
Searches for Atmospheric Long-Lived Particles
Creators: name: Argüelles, Carlos
name: Coloma, Pilar
name: Hernández, Pilar
name: Muñoz, Víctor
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Long-lived particles are predicted in extensions of the Standard Model that involve relatively light but very weakly interacting sectors. In this paper we consider the possibility that some of these particles are produced in atmospheric cosmic ray showers, and their decay intercepted by neutrino detectors such as IceCube or Super-Kamiokande. We present the methodology and evaluate the sensitivity of these searches in various scenarios, including extensions with heavy neutral leptons in models of massive neutrinos, models with an extra $U(1)$ gauge symmetry, and a combination of both in a $U(1)_{B-L}$ model. Our results are shown as a function of the production rate and the lifetime of the corresponding long-lived particles.
description: 33 pages, 19 figures. v2: Minor changes, references added. Version accepted for publication in JHEP
Conus monile Hwass
Creators: name: Franklin, J. Benjamin
name: Subramanian, K. A.
name: Fernando, S. Antony
name: Krishnan, K. S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Conidae
Conus
Conus monile

description: 42. Conus monile Hwass in Bruguière, 1792 (Figure 43)
 Conus monile Hwass in Bruguière, 1792: 646–647, no. 45 (lectotype, MHNG (70 x 36 mm) (Kohn 1968); "Ocean Asiatique").
 Cucullus cereolus Röding, 1798: 44, no. 557/67 (representation of lectotype, Chemnitz 1788: pl. 140, fig. 1301 (52 x 25 mm) (Kohn 1975); locality unknown).
 Material examined: MBMCS142, 157 specimens, SL 66–120 mm; SW 35–42 mm.
 Description. Shell medium to large, moderately heavy, and conical with high gloss; sides nearly straight. Body whorl conical, outline variably convex over adapical fourth to third and straight below. Body whorl with a few weak spiral ridges above the base and sometimes conspicuous axial threads. Shoulder broad, carinate to angulate, concave above. Spire of low to moderate height.
Ground colour white or cream. Body whorl suffused or spirally banded with pale orange or pink. Spiral rows of brown dots, dashes and variously shaped spots extend from base to shoulder but vary in number and arrangement, often concentrated at both sides of the centre. Sometimes dark markings fuse into axial flames or blotches. Base pale orange or brown. Aperture white. Periostracum yellowish brown, thin, translucent to opaque, smooth or with fine axial ridges.
 Distribution. Gravely (1942) first reported this species from Madras. Subsequently, Hornell (1949) recorded it from India without giving precise locality data. Kohn (1978) collected two specimens trawled off PortoNovo. He also reported museum specimens dredged off Madras (at MGM) and Tuticorin (at BMNH). Conus monile has also been recorded from Bombay along the west coast (Subrahmanyam et al. 1952).
The specimens reported herein were collected from various stations (Table 6) of the TamilNadu Coast by trawling in 9–40 m, mainly on sand and sandy-mud bottoms. However, at Periyakuppam it was collected in 5– 15 m.
 Remarks. Although the shell shape is generally uniform, few specimens showed markedly elevated spire, and there is considerable variation in the colour pattern of the body whorl (Figure 62O). The occurrence of this species around the northern region suggests its preference for shallow sand and sandy-mud bottoms.
description: Published as part of Franklin, J. Benjamin, Subramanian, K. A., Fernando, S. Antony & Krishnan, K. S., 2009, 2250, pp. 1-63 in Zootaxa 2250 on page 41
Quantum Trajectories for Realistic Photodetection I: General Formalism
Creators: name: Warszawski, P.
name: Wiseman, H. M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum trajectories describe the stochastic evolution of an open quantum system conditioned on continuous monitoring of its output, such as by an ideal photodetector. In practice an experimenter has access to an output filtered through various electronic devices, rather than the microscopic states of the detector. This introduces several imperfections into the measurement process, of which only inefficiency has previously been incorporated into quantum trajectory theory. However, all electronic devices have finite bandwidths, and the consequent delay in conveying the output signal to the observer implies that the evolution of the conditional state of the quantum system must be non-Markovian. We present a general method of describing this evolution and apply it to avalanche photodiodes (APDs) and to photoreceivers. We include the effects of efficiency, dead time, bandwidth, electronic noise, and dark counts. The essential idea is to treat the quantum system and classical detector jointly, and to average over the latter to obtain the conditional quantum state. The significance of our theory is that quantum trajectories for realistic detection are necessary for sophisticated approaches to quantum feedback, and our approach could be applied in many areas of physics.
description: 15 pages. Part I of a two-part paper
Consistent time-to-failure tests and analyses of adhesive anchor systems
Creators: name: Nincevic, Kresimir
name: Boumakis, Ioannis
name: Meissl, Stefan
name: Wan-Wendner, Roman
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Motivated by tunnel accidents in the recent past several investigations into the sustained load behavior of adhesive anchors have been initiated. Nevertheless, the reliable life-time prediction of bonded anchor systems based on a relatively short period of testing still represents an unsolved challenge due to the complex non-liner viscoelastic behaviour of concrete and adhesives alike. This contribution summarizes the results of a comprehensive experimental investigation and systematically carried out time-to-failure analysis performed on bonded anchors under sustained tensile load. Two different adhesive materials that find widespread application in the building industry were used, one epoxy and one vinylester based. Performed experiments include full material characterizations of concrete and the adhesives, bonded anchor pull-out tests at different loading rates, and time-to-failure sustained load tests. All anchor tests are performed in a confined configuration with close support. After a thorough review of available experimental data and analysis methods in the literature the experimental data is presented with the main goals to (i) derive a set of recommendations for efficient time to failure tests, and (ii) to provide guidance for the analysis of load versus time-to-failure test data. Finally,a new approach based on a sigmoid function is proposed and compared to the established regression models. The analyses indicate a better agreement with the physics of the problem and, thus, more reliable extrapolations.
description: 42 pages, 13 figures
Copyright in Published Editions: A History of a Declining Right
Creators: name: Matulionyte, Rita
Publisher: name: Monash University
Year: 2019
Subjects: subject: Law
subject: FOS: Law

description: The right to published editions was introduced in the Copyright Act 1968 (Cth) in order to prevent the unfair copying of typographical layouts of published editions of books in the public domain. The initial rationale, its actual effectiveness, and its relevance today has attracted very little attention among commentators. Historical analysis shows that the right was introduced into Australian copyright law without much discussion or engagement. Even today it is difficult to find evidence that there was ever an actual need for a right of this nature in Australia, or that it has had any positive effects on the local publishing industry since. This article demonstrates that despite its original intention, some industries today have moved to exploit the right by reinterpreting it to protect their own financial interests. This article concludes with some lessons that could be learned from the history of published edition copyright in the context of current copyright policy discussions — particularly in relation to the newly proposed rights for news publishers.
B cell subset distribution in human bone marrow is stable and similar in left and right femur: An instructive case
Creators: name: Wiedemann, Annika
name: Lino, Andreia C.
name: Dörner, Thomas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: bone marrow
subject: B cell
subject: long-lived plasma cells
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The bone marrow (BM) is, in addition to being the site of B cell development, a tissue that harbors long-lived plasma cells (PC), the cells that protect the body against foreign antigens by continuous production of antibodies. Nothing is known about the long-term stability and functionality of both B cells and PC in the BM at the individual donor level since repeated sampling possibilities outside of oncology are scarce. Here, we had the opportunity to obtain BM samples from a patient undergoing bilateral total hip arthroplasty half a year apart. We observed that the frequencies of the analyzed B cell and PC subsets were similar despite a time of six months in between and sampling on left and right side of the body. Additionally, B cell receptor stimulation led to comparable results. Our data suggest that composition and functionality of B cells are stable in the BM of adults at the individual donor level.
Instituciones y costes de transacción en la gestión de pesquerías: el caso de Grand Sole
Creators: name: Torreiro, Marcos
name: Alvarez, Ana B.
name: Malvido, Carlos
name: Torreiro, Marcos
name: Alvarez, Ana B.
name: Malvido, Carlos
Publisher: name: Unknown
Year: 2003
Subjects: subject: Agricultural and Food Policy
subject: Financial Economics
subject: Land Economics/Use
subject: Politica pesquera comun
subject: pesquerias de Grand Sole
subject: sistemas de gestion
subject: nueva economia institucional
subject: costes de transaccion
subject: Common fisheries policy
subject: Grand Sole fishery
subject: management systems
subject: new institutional economics
subject: transaction costs

description: La adhesión de España a la CEE en 1986 supuso la definición de derechos de pesca con la finalidad de limitar el acceso de los buques españoles a las pesquerías del Grand Sole (divisiones CIEM Vb, VI, VII, VIIIabde), explotadas mayoritariamente por buques procedentes de las regiones de Galicia y el País Vasco. Desde entonces, han surgido diferentes estrategias (acumulación de derechos, exportación de buques, etc.) para ajustar las capacidades de pesca a las disponibilidades de cuotas. En la actualidad, el sistema ha culminado en el establecimiento de derechos de pesca individuales y transferibles. Sin embargo, los pescadores han optado por delegar en su Asociación la gestión de sus derechos. Este trabajo tiene por objetivo analizar la evolución del sistema de gestión en esta pesquería adoptando la metodología de la Nueva Economía Institucional...Spanish accession to the EEC in 1986 meant the definition of fishing rights with the aim of restricting the activity of Spanish vessels in the Grand Sole fishery (ICES Vb, VI, VII, VIIIabde), mainly exploited by vessels based in two regions, Galicia and the Basque Country. Since then, different strategies (accumulation of fishing rights, export of fishing vessels, etc.) arose out in order to adequate the fishing capacity to the availability of quotas. Nowadays, the system has culminated in the setting-up of individual and transferable fishing rights. However, fishermen have preferred to delegate the management of their rights in the hands of their Associations. The purpose of this paper is to analyse the evolution of the management system in the fishery from the New Institutional Economics point of view.
Halova et al. Supplementary Data Table 1–17. from A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans
Creators: name: Halova, Lenka
name: Cobley, David
name: Franz-Wachtel, Mirita
name: Wang, Tingting
name: Morrison, Kaitlin R.
name: Krug, Karsten
name: Nalpas, Nicolas
name: Maček, Boris
name: Hagan, Iain M.
name: Humphrey, Sean J.
name: Petersen, Janni
Publisher: name: The Royal Society
Year: 2021

description: Excel sheets including all detailed information about phosphorylation sites identified in this study.
On the critical behavior of the one dimensional, diffusive pair contact process
Creators: name: Odor, Geza
Publisher: name: arXiv
Year: 2002
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The phase transition of the one-dimensional, diffusive pair contact process (PCPD) is investigated by N cluster mean-field approximations and high precision simulations. The N=3,4 cluster approximations exhibit smooth transition line to absorbing state by varying the diffusion rate D with beta_2=2 mean-field order parameter exponent of the pair density. This contradicts with former N=2 results, where two different mean-field behavior was found along the transition line. Extensive dynamical simulations on L=10^5 lattices give estimates for the order parameter exponents of the particles for 0.05 <= D <= 0.7. These data can support former two distinct class findings. However the gap between low and high D exponents is narrower than estimated previously and the possibility for interpreting numerical data as a single class behavior with exponents alpha=0.21(1), beta=0.41(1) assuming logarithmic corrections is shown. Finite size scaling and cluster simulation results are also presented.
description: 6 pages, 8 figures included, minor changes
Gravitational wave stochastic background from cosmological particle decay
Creators: name: Allen, Bruce
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We assume that the cosmological dark matter is composed of massive neutral scalar particles that decay into two massless particles. The decay produces a stochastic background of gravitational waves (GWs) via a 'memory effect' mechanism. We calculate the spectral amplitude and slope of the resulting background, which is frequency independent (flat). We discuss its potential observability and show that the resulting background might dominate the cosmological GW background at frequencies above about 10 GHz. Penrose has proposed a cosmological model in which dark matter particles have the Planck mass and decay into two gravitons. For these, the spectrum has an additional 'direct' contribution from the decay products, which we also calculate. At low frequencies, this direct contribution also has a flat spectrum but with a much smaller amplitude than the memory part.
description: Final published version (Open Access)
Localization of metric fluctuations on scalar branes
Creators: name: Giovannini, Massimo
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The localization of metric fluctuations on scalar brane configurations breaking spontaneously five-dimensional Poincaré invariance is discussed. Assuming that the four-dimensional Planck mass is finite and that the geometry is regular, it is demonstrated that the vector and scalar fluctuations of the metric are not localized on the brane.
description: 8 pages in Latex style
Overgrowth of the lower limb after treatment of developmental dysplasia of the hip: incidence and risk factors in 101 children with a mean follow-up of 15 years
Creators: name: Yoon, Chan
name: Shin, Chang Ho
name: Kim, Dong Ook
name: Park, Moon Seok
name: Yoo, Won Joon
name: Chung, Chin Youb
name: Choi, In Ho
name: Tae-Joon Cho
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Background and purpose — There are few studies on overgrowth of the affected limb after treatment of developmental dysplasia of the hip (DDH). We investigated the incidence of overgrowth and its risk factors in DDH patients. Patients and methods — 101 patients were included in this study. Overgrowth was defined by 2 criteria: when the height of the femoral head of the affected side was higher than that of the contralateral side by more than 10 mm, or by more than 15 mm. The potential risk factors of distinct overgrowth were retrospectively examined using multivariable analysis. Results — When overgrowth was defined as femoral head height difference (FHHD) > 10 mm, its incidence was 44%, and only femoral osteotomy was identified as a significant risk factor with a relative risk (RR) of 1.6 (95% confidence interval [CI] 1.0–2.5). When overgrowth was defined as FHHD > 15 mm, its incidence was 23%, and femoral osteotomy was identified as the only significant risk factor with an RR of 2.3 (CI 1.2–4.5). Overgrowth developed more frequently in patients who underwent femoral osteotomy at the age of 2 to 4 years (87%) than in the others (46%) (p = 0.04). Interpretation — Overgrowth of the affected limb is common in DDH patients. Patients who underwent femoral osteotomy, especially at the age of 2 to 4 years, may require careful follow-up because of the substantial risk for overgrowth.
Quasi free electro fission of 238U
Creators: name: Likhachev, V. P.
name: Mesa, J.
name: Arruda-Neto, J. D. T.
name: Carlson, B. V.
name: Deppman, A.
name: Hussein, M. S.
name: Nesterenko, V. O.
name: Garcia, F.
name: Rodriguez, O.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present the result of a theoretical study of the quasi free electrofission of $^{238}$U. The exclusive differential cross sections for the quasi free scattering reaction stage have been calculated in PWIA, using a Macroscopic-Microscopic approach for the description of the proton bound states. The nuclear shape was parametrized in terms of cassinian ovaloids. The equilibrium deformation parameters have been calculated by minimizing the total nuclear energy. In the calculation the axially deformed Woods-Saxon single particle potential was used. The obtained single particle momentum distributions were averaged over the nuclear symmetry axis direction. The occupation numbers were calculated in the BCS approach. The fissility for the single hole excited states of the residual nucleus $^{237}$% Pa was calculated on the statistical theory grounds both without taking into account the pre-equilibrium emission of the particle, and with preequilibrium emission in the framework of the exciton model.
description: 24 pages, 10 figures, 1 table. Accepted in Physical Review C
Peptidoglycan Recognition Protein 2 Regulates Neutrophil Recruitment Into the Lungs After Streptococcus pneumoniae Infection
Creators: name: Dabrowski, Alexander N.
name: Conrad, Claudia
name: Behrendt, Ulrike
name: Shrivastav, Anshu
name: Baal, Nelli
name: Wienhold, Sandra M.
name: Hackstein, Holger
name: N'Guessan, Philippe D.
name: Aly, Sahar
name: Reppe, Katrin
name: Suttorp, Norbert
name: Zahlten, Janine
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: infectious diseases
subject: innate immunity
subject: mouse
subject: PGRP
subject: PGLYRP2
subject: pneumonia
subject: S. pneumoniae
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Peptidoglycan (PGN) recognition proteins (PGLYRPs) are a highly conserved group of host defense proteins in insects and mammals that sense bacterial cell wall PGN and act bactericidally or cleave PGN by amidase function. Streptococcus (S.) pneumoniae is one of the top five killers worldwide and causes, e.g., pneumonia, endocarditis, meningitis and sepsis. S. pneumoniae accounts for approximately 1.5-2 million deaths every year. The risk of antibiotic resistance and a general poor prognosis in young children and elderly people have led to the need for new treatment approaches. To the best of our knowledge, there is no report on the relevance of PGLYRP2 in lung infections. Therefore, we infected mice deficient for PGLYRP2 transnasally with S. pneumoniae and examined the innate immune response in comparison to WT animals. As expected, PGLYRP2-KO animals had to be sacrificed earlier than their WT counterparts, and this was due to higher bacteremia. The higher bacterial load in the PGLYRP2-KO mice was accomplished with lower amounts of proinflammatory cytokines in the lungs. This led to an abolished recruitment of neutrophils into the lungs, the spread of bacteria and the subsequent aggravated course of the disease and early mortality of the PGLYRP2-KO mice. These data suggest a substantial role of PGLYRP2 in the early defense against S. pneumoniae infection, and PGLYRP2 might also affect other infections in the lungs.
Quantum Mechanics in Curved Configurational Space
Creators: name: Tagirov, E. A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Different approaches are compared to formulation of quantum mechanics of a particle on the curved spaces. At first, the canonical, quasi-classical and path integration formalisms are considered for quantization of geodesic motion on the Rimannian configurational spaces. A unique rule of ordering of operators in the canonical formalism and a unique definition of the path integral are established and, thus, a part of ambiguities in the quantum counterpart of geodesic motion is removed. A geometric interpretation is proposed for non-invariance of the quantum mechanics on coordinate transformations. An approach alternative to the quantization of geodesic motion is surveyed, which starts with the quantum theory of a neutral scalar field. Consequences of this alternative approach and the three formalisms of quantization are compared. In particular, the field theoretical approach generates a deformation of the canonical commutation relations between coordinates and momenta of a prticle. A possible cosmological consequence of the deformation is presented in short. Key words: quantum mechanics, Riemannian space, geodesic motion, deformation.
description: 31 pages
Risk Management by University Lawyers in Work Integrated Learning Programs
Creators: name: Cameron, Craig
Publisher: name: Monash University
Year: 2019
Subjects: subject: Law
subject: FOS: Law

description: The strategic expansion of work integrated learning (‘WIL’) programs by Australian universities is not without legal risk. The primary sources of that legal risk are the participation of third party entities that host students in the workplace and the placement of students in a workplace environment that they may be unfamiliar with. Managing the legal risks associated with WIL is not only a commercial imperative, but is mandatory under higher education law. University lawyers, a relatively unknown category of in-house counsel, have a central role in risk management. A case study involving 13 Australian university lawyers represents the first known systematic study of risk management in WIL from the perspective of university lawyers. The insights and recommendations provided by university lawyers can educate stakeholders about risk management and the role of university lawyers, and can be used as a basis for evaluating and improving risk management in WIL programs.
A Growth Factor-Free Co-Culture System of Osteoblasts and Peripheral Blood Mononuclear Cells for the Evaluation of the Osteogenesis Potential of Melt-Electrowritten Polycaprolactone Scaffolds
Creators: name: Hammerl, Andreas
name: Diaz Cano, Carlos E.
name: De-Juan-Pardo, Elena M.
name: Griensven, Martijn Van
name: Poh, Patrina S. P.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: melt electrowriting
subject: bone tissue engineering
subject: calcium phosphate
subject: human primary cells
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Scaffolds made of biodegradable biomaterials are widely used to guide bone regeneration. Commonly, in vitro assessment of scaffolds' osteogenesis potential has been performed predominantly in monoculture settings. Hence, this study evaluated the potential of an unstimulated, growth factor-free co-culture system comprised of osteoblasts (OB) and peripheral blood mononuclear cells (PBMC) over monoculture of OB as an in vitro platform for screening of bone regeneration potential of scaffolds. Particularly, this study focuses on the osteogenic differentiation and mineralized matrix formation aspects of cells. The study was performed using scaffolds fabricated by means of a melt electrowriting (MEW) technique made of medical-grade polycaprolactone (PCL), with or without a surface coating of calcium phosphate (CaP). Qualitative results, i.e., cell morphology by fluorescence imaging and matrix mineralization by von Kossa staining, indicated the differences in cell behaviours in response to scaffolds' biomaterial. However, no obvious differences were noted between OB and OB+PBMC groups. Hence, quantitative investigation, i.e., alkaline phosphatase (ALP), tartrate-resistant acid phosphatase (TRAP) activities, and gene expression were quantitatively evaluated by reverse transcription-polymerase chain reaction (RT-qPCR), were evaluated only of PCL/CaP scaffolds cultured with OB+PBMC, while PCL/CaP scaffolds cultured with OB or PBMC acted as a control. Although this study showed no differences in terms of osteogenic differentiation and ECM mineralization, preliminary qualitative results indicate an obvious difference in the cell/non-mineralized ECM density between scaffolds cultured with OB or OB+PBMC that could be worth further investigation. Collectively, the unstimulated, growth factor-free co-culture (OB+PBMC) system presented in this study could be beneficial for the pre-screening of scaffolds' in vitro bone regeneration potential prior to validation in vivo.
Real World Simulation of Life on Mars
Creators: name: Garg, Rishabh
Publisher: name: Zenodo
Year: 2014
Subjects: Earth, Mars, Life Support System, Real world simulation of Life on Mars.

description: Real-world Mock-up of Earth & Mars facilitated the peer group to understand how Nature shields them from the hostile spell of cosmic assaults and supplies their day-to-day needs. Students could appreciate this fact when they imagined life on an alien star, a million miles away from their home planet, struggling with a strange, non-supportive and non-sustainable environment.
description: National Aeronautics and Space Administration | US
Conus achatinus Gmelin 1791
Creators: name: Franklin, J. Benjamin
name: Subramanian, K. A.
name: Fernando, S. Antony
name: Krishnan, K. S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Conidae
Conus
Conus achatinus

description: 1. Conus achatinus Gmelin, 1791 (Figure 2)
 Conus achatinus Gmelin, 1791: 3388, no. 25 (representation of lectotype, Chemnitz 1788: pl. 142, fig. 1317 (74 x 42 mm) (Kohn 1966); "Oceano americano", corrected to " Java " (Coomans et al. 1979b)).
 Conus achatinus Hwass in Bruguière, 1792: 671–673, no. 66 (lectotype, MHNG (68.5 x 40.5 mm) (Kohn 1968); "Océan asiatique").
 Conus ranunculus Hwass in Bruguière, 1792: 671, no. 65 (holotype, MHNG (45 x 23 mm) (Kohn 1968); "Océan Amériquain").
 Cucullus ventricosus Röding, 1798: 49, no. 623/114.
 Conus achatinus var. infumata Dautzenberg, 1937: 12 (representation of lectotype, Chemnitz 1788: pl. 142, fig. 1320 (60 x 31 mm) (Walls 1979)).
 Material examined: MBMCS 101, 5 specimens, SL 35–65 mm; SW 17–32 mm.
 Description. Shell moderately solid, outline convex. Aperture wider at base than near shoulder. Spire of moderate height. Colour of body whorl olive or orange red to blackish brown, clouded with scattered white to dull yellowish flammules and blotches; broad band at centre with similar pattern. Spiral uniform thin lines of dark brown interrupted by white dots and dashes run from shoulder to base. Aperture bluish white; exterior dark colour pattern visible as a band along interior border of lip. Periostracum brown and opaque. End of siphon dark brown, proboscis deep orange to red.
 Distribution. Melvill & Abercrombie (1893) first reported C. achatinus from India as ‘ C. monachus Linnaeus var. achatinus Chemnitz’. C. achatinus was reported to be widely distributed along northwest coast from Okha southward to Goa (Melvill & Abercrombie 1893; Abercrombie 1893; Melvill & Standen 1901; Hornell & Tomlin 1951; Subrahmanyam et al. 1952; Kohn 1978). Ray (1949) reported two specimens from the east coast.
The specimens reported herein were collected from Keelakarai (Table 6) by trawling in 5–20 m and by diving in 10 m. Fifty-eight specimens from Colaba, Bombay were collected by hand at low tide.
 Remarks. In Colaba, Bombay (18 0 53’N 72 0 48’E), C. achatinus (piscivore) occurs together with C. hyaena (vermivore) on the upper intertidal region of the west coast, but it occurs only subtidally on the east coast.
 Four types of shell colour patterns were observed among C. achatinus found on the west coast (Figure 62A, B, C & D) whereas only one type was observed in the east (Figure 2). The size range was similar between both coast specimens.
description: Published as part of Franklin, J. Benjamin, Subramanian, K. A., Fernando, S. Antony & Krishnan, K. S., 2009, 2250, pp. 1-63 in Zootaxa 2250 on pages 12-17
Effective spin distribution of black hole mergers in triples
Creators: name: Fragione, Giacomo
name: Kocsis, Bence
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Many astrophysical scenarios have been proposed to explain the several black hole (BH) and neutron star binary mergers observed via gravitational waves (GWs) by the LIGO-Virgo collaboration. Contributions from various channels can be statistically disentangled by mass, spin, eccentricity and redshift distributions of merging binaries. In this paper, we investigate the signatures of BH-BH binary mergers induced by a third companion through the Lidov-Kozai mechanism in triple systems. We adopt different prescriptions for the supernovae natal kicks and consider different progenitor metallicities and initial orbital parameters. We show that the typical eccentricity in the LIGO band is $0.01$-$0.1$ and that the merger rate is in the range $0.008-9 \ \mathrm{Gpc}^{-3}\ \mathrm{yr}^{-1}$, depending on the natal kick prescriptions and progenitor metallicity. Furthermore, we find that the typical distribution of effective projected spin is peaked at $χ_{\rm eff}\sim 0$ with significant tails. We show that the triple scenario could reproduce the distribution of $χ_{\rm eff}$. We find that the triple channel may be strongly constrained by the misalignment angle between the binary component spins in future detections with spin precession.
description: 13 pages, 8 figures, 2 tables, accepted by MNRAS. arXiv admin note: text overlap with arXiv:1907.08614