cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Irritation und Werbung?
Creators: name: Sackl, Andreas
Year: 2012

description: Obwohl die Werbeforschung seit Jahrzehnten Ergebnisse für Theoretiker und Praktiker unterschiedlichster Disziplinen liefert, werden diese anscheinend nicht immer konse- quent in der Gestaltung von Werbeschaltungen berücksichtigt. Regelmäßig kommt es zu negativen Bewertungen seitens der Rezipienten bezüglich konsumierter Werbeformate. Die aktuelle Forschungsliteratur führt anhand empirischer Untersuchungen diverse Ursachen hierfür an. So sorgen beispielsweise unrealistische Handlungssituationen oder übertrieben positiv dargestellte Produkteigenschaften für negative Rezeptions- erfahrungen. Ebenso führen sozial unerwünschte Handlungsweisen, etwa das herablassende Verhalten einer Mutter gegenüber ihrer Tochter, zu negativen Bewertungen. Unabhängig von gestalterischen Aspekten, kann das beworbene Produkt an sich zu Irritationen führen, etwa bei der Anpreisung von Hämorridensalben. Einige der mittels Literaturrecherche erstellten Irritationsquellen lassen sich sehr gut mit der Theorie des kommunikativen Handelns von Habermas verbinden. Die Verwendung fremdsprachlicher Ausdrücke kann zu Problemen hinsichtlich des Geltungsanspruchs Verständlichkeit, die Darstellung unrealistischer Situationen kollidiert mit dem Anspruch der Wahrheit und unerwünschtes soziales Verhalten verletzt die normative Richtigkeit. Offensichtlich wird der Geltungsanspruch Wahrhaftigkeit bezogen auf Werbekom- munikationsprozesse von den involvierten Rezipienten nicht eingefordert. Die Ergebnisse der Literaturrecherche wurden mittels eigener Empirie verfeinert und erweitert. Anhand des von mir entwickelte Onlinetool SpotInsight wurden vier Werbe- spots von den teilnehmenden Probanden kommentiert. Mittels der qualitativen Inhaltsanalyse nach Mayring wurden jene Kommentare ausgewählt und zusammengefasst, welche sich negativ über Aspekte des jeweiligen Werbespots äußerten. Die mittels Literaturrecherche und eigener Empirie erstellten, allgemeinen Irritationsquellen können Praktikern helfen, potentielle, nicht erwünschte negative Rezeptionsprozesse bereits im Gestaltungsprozess von Werbeformaten zu verhindern.
title: CLONING OF THE 1.4-kb mRNA SPECIES OF HUMAN COMPLEMENT FACTOR H REVEALS A NOVEL MEMBER OF THE SHORT CONSENSUS REPEAT FAMILY RELATED TO THE CARBOXY TERMINAL OF THE CLASSICAL 150-kDa MOLECULE
Creators: name: Estaller, C.
name: Koistinen, V.
name: Schwaeble, W.
name: Dierich, Manfred P.
name: Weiss, Elisabeth H.
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 1991
Subjects: subject: 570

description: Three factor H mRNA species of 4.3 kb, 1.8 kb,and 1.4 kb are constitutively expressed in humanliver. Having previously characterized full-lengthcDNA clones derived from the 4.3-kb and 1.8-kbfactor mRNA, we report here the isolation and eucaryoticexpression of full-length cDNA clones codingfor the 1.4-kbm RNA species. The 1266-bp cDNAcodes for a polypeptide of 330 amino acids andcontains two polyadenylation signals and a shortpoly(A)+tailT. he protein is composed of a leaderpeptide followed by five short consensus repeat domains.It shows a hybrid structure with the lastthree domains being almost identical to the carboxy-terminal of thcel assical 1 BO-kDa factor H moleculeand the two first domains representing uniqueshort consensus repeat structures. Eucaryoticexpression in COS7 cells revealed two polypeptidesderived from one cDNA clone that area lso found inhuman serum. Differences between the cDcNloAn eswithin the last three domains indicate two distinct,possibly allelic sequences that, in addition, differfrom the authentic 150-kDa factor H sequence.Southern blot results support the notion that the4.3-kb factor H and the 1.4-kb factor H-relatedmRNA are transcribed from two separate but highlyhomologous genes.Factor H, a glycoprotein of 150,000
Gegen dem Draat-Schmittli
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1830
Subjects: Vedute
Barke

description: Am Limmatufer, auf der linken Seite, ist das "Drahtschmidli", eine Häusergruppe, die gegen Ende des 18. Jahrhunderts gebaut wurde sichtbar. Im Vordergrund ist eine Barke dargestellt
description: Datierung gemäss handschriftlichem Vermerk auf der Rückseite des Blattes
20th Century American Family Drama: An Exploration of Image of Loss
Publisher: name: The University Of Kurdistan
Year: 2019

description: The purpose of this study is to explore the image of loss in modern American drama\nin the theme of family. The image of loss prevails the post-war era of American\ndrama in three levels of psychological, physical, and moral space. This image is\nclearly observable in two of the prominent works of the era, Tennessee Williams’\nThe Glass Menagerie and Arthur Miller’s Death of a Salesman. Moreover, this\nimage of loss is closely connected with the notion of time. The familial breakdown\nappears as a sustaining motif that plays a central role in the psychologically\nshattered personality of the major characters, as a result of the profound changes\nin the American post-war society and family. World War II was a milestone in the\nsociety as a whole, and in the family as a smaller society, and correspondingly\namong the people as entities which the image of loss seemed inseparable from.\nAmerican post-War drama fully represents the tough conditions of that era\nparticularly in the themes of familial breakdown and the image of loss.
title: Human complement factor H. Two factor H proteins are derived from alternatively spliced transcripts
Creators: name: Estaller, Cornelia
name: Schwaeble, Wilhelm
name: Dierich, Manfred P.
name: Weiss, Elisabeth H.
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 1991
Subjects: subject: 570

description: The human complement factor H is an important component in the control of thealternative pathway of complement activation. We have previously shown that atleast three factor H homologous mRNA species of 4.3 kb, 1.8 kb and 1.4 kb inlength are constitutively expressed in human liver. In addition, several factor Hrelatedproteins have been detected in human sera using antibodies directedagainst the classical human factor H glycoprotein of 150 kDa.The structure of theadditional polypeptides has not been shown so far. Circumstantial evidencesuggests that the 1.8-kb mRNA might encode the 43-kDa factor H-likepolypeptide. Here we report the isolation, characterization and eukaryoticexpression of the first full-length cDNA representing the major 4.3-kb mRNAand the 1.8-kb mRNA of human factor H. We show that the 4.3-kb transcriptencodes the 150-kDa-factor H glycoprotein and the 1.8-kb mRNA the 43-kDafactorH polypeptide. The identity of the two cDNA in a region of 1400nucleotides suggests that the two factor H-related transcripts are derived fromone gene by a process of alternative splicing.
[Drahtschmidli]
Creators: name: Keller, Heinrich
Publisher: name: [s.n.]
Year: 1830
Subjects: Vedute

description: Ansicht gegen das Drahtschmidli vom linken Limmatufer aus
description: [Heinrich Keller?]
description: Datierung und Zuschreibung gemäss handschriftlichem Vermerk auf der Rückseite des Blattes
Progressive  supranuclear palsy
Creators: name: Paez Camarena, Sheyla
Publisher: name: EURORAD
Year: 2017
Subjects: subject: Neuroradiology brain
subject: MR
subject: Perception image
subject: Dementia

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 61 years
description: Clinical History: A 61-year-old male presented gait disturbances, slowness and falls while walking since over 2 years ago, its symptoms were insidious onset and progressive course. Also, he started with alteration of eye movements since 1 year ago. Final Diagnosis: Progressive supranuclear palsy
Klösterli auf dem Zürichberg
Creators: name: Keller, Heinrich
Publisher: name: [s.n.]
Year: 1811

description: Ansicht der Überreste des Kreuzganges des Klosters St. Martin
description: [Heinrich Keller]
description: Zuschreibung gemäss handschriftlichem Vermerk auf der Rückseite des Passepartouts
Graphical Overview from May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
Creators: name: Hancock, Fran
name: Rosas, Fernando E.
name: Mediano, Pedro A. M.
name: Luppi, Andrea I.
name: Cabral, Joana
name: Dipasquale, Ottavia
name: Turkheimer, Federico E.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Biophysics
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 60114 Systems Biology
subject: FOS: Biological sciences
subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: 69999 Biological Sciences not elsewhere classified

description: Graphical overview illustrating the 4Cs in empirical and model data
[Quodlibet mit Schweizer Ansichten]
Creators: name: Hädener, Johannes
Publisher: name: [s.n.]
Year: 1795
Subjects: Herisau

description: Trompe-l'oeil eines Holzbrettes, auf das mit rotem Sigellack Ansichtszeichnungen und Brieffragmente aufgeklebt scheinen
description: Folgende fiktive Blätter sind dargestellt: 1. Ein Brief an Jean-Jacques Rousseau. Er beginnt mit den Worten: "Monsieur [...] Monsieur Jean Jaques Rou[...]"; 2. eine Ansicht des ehemaligen Austragungsortes der Schlacht bei Vögelinsegg (1403) mit der Bildunterschrift "Vögelins Egg allwo die Schlacht 1043 [sic] gehalten, durch diesen Sieg hat der Canton Ap[penzell ...]"; 3. eine Ansicht der Bruggmühle in Bischofszell mit der Bildunterschrift "Brugg Mühle in BischofZell"; 4. eine Ansicht von Gersau mit der Bildunterschrift "Bourg de Gersau petite Republique sur le Lac de Lucerne des Quatres Cantons"; 5. ein Ausschnitt einer Ansicht der Kirche Herisau, beschriftet mit "Kirch Hof Herisau"; 6. ein Fragment mit dem Backronym "CANONICUS", bestehend aus den Wörtern "Creatus", "Ad", "Nutum", "O[...]as", "Nisi", "In", "Curam", "Ventris", "Sui"; 7. Ein Notizblatt mit der Aufschrift "les Paresseux Suent a la Vue de l'ouvrage" und 8. eine Ansicht des Staubbach-Wasserfalls bei Lauterbrunnen mit der Bildunterschrift "Auss Sicht im Thall Lauterbrun von dem Staub bach im Canton Bern"
description: J. Hädener ad. nat. del.
description: Aus der Sammlung Leonhard Ziegler zum Egli (1782-1854) Exemplar der Zentralbibliothek Zürich, Graphische Sammlung und Fotoarchiv
[Schlösschen Susenberg]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1800
Subjects: Zürich

description: Ansicht des Zürichbergs mit dem Schlösschen Susenberg rechts im Hintergrund. Auf einem Pfad im Vordergrund ist eine sitzende Frau mit einem Holzbottich dargestellt
description: [anonym]
Supplementary Material from May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
Creators: name: Hancock, Fran
name: Rosas, Fernando E.
name: Mediano, Pedro A. M.
name: Luppi, Andrea I.
name: Cabral, Joana
name: Dipasquale, Ottavia
name: Turkheimer, Federico E.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Biophysics
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: 60114 Systems Biology
subject: FOS: Biological sciences
subject: 60199 Biochemistry and Cell Biology not elsewhere classified
subject: 69999 Biological Sciences not elsewhere classified

description: Supplementary Table S 1 Examples of graph theory metrics that are commonly employed in neuroscience. Note that a vast number of graph-theoretic metrics exist, both at the level of individual nodes and the whole network. Also note that many such metrics may allow for generalizations to weighted, signed, or directed networks
title: Modeling Exposure-Lag-Response Associations with Penalized Piece-wise Exponential Models
Creators: name: Bender, A.
name: Scheipl, F.
name: Küchenhoff, H.
name: Day, A. G.
name: Hartl, W.
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2016
Subjects: subject: Survival analysis, piece-wise exponential model, exposure-lag-response association
subject: 510

description: We present a novel approach for the flexible modeling of exposure-lag-response associations, i.e., time-to-event data where multiple past exposures are cumulatively associated with the hazard after a certain temporal delay. Our method is based on piece-wise exponential models and allows estimation of a wide variety of effects, including potentially smooth and time-varying effects as well as cumulative effects with leads and lags, taking advantage of the advanced inference methods that have recently been developed for generalized additive mixed models.
title: „Wenn kein Hahn mehr danach kräht“: Vom Bildungspotenzial biblischer Texte
title: Editorial
titleType: Other
Creators: name: Lehner-Hartmann, Andrea
name: Dangl, Oskar
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 5-7; ISSN: 1018-1539;
Aussicht von unserem Fenster
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1869
Subjects: Zürich

description: Ansicht von Hottingen mit Blick gegen den Zürichsee und die Alpen. In der Bildmitte ist die Kirche Neumünster erkennbar
description: J.
description: Datierung gemäss handschriftlichem Vermerk auf der Rückseite des Blattes
description: Rückseite, unten links: handschriftlich notierte Nummer "4195-42"
title: Als Jona drei Tage im Walfisch war ‒ oder: Vom Zähneputzen!
title: Intertextuelle bibeldidaktische Zugänge in der Grundschule
titleType: Other
Creators: name: Ballhorn, Egbert
name: Gärtner, Claudia
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 18-26; ISSN: 1018-1539;
title: Verständigungserfolg der ‚Anti Corporate Campaign‘ Überparteiliche Plattform gegen die Westring Transitautobahn mitten durch Linz
Creators: name: Haudum, Christina
Year: 2012

description: Öffentlichkeitsarbeit hat in den letzten Jahren die Vorteile des World Wide Web für sich entdeckt. Immer mehr Unternehmen springen auf den Online-Zug auf und nun haben auch kleinere Gruppierungen wie Bürgerinitiativen das Internet als Plattform für ihre Forderungen und Aktionen entdeckt. Es formierten sich Anti Corporate Campaigns, sogenannte Protestkampagnen, die gegen ein Unternehmen oder bestimmtes Vorhaben auftreten und so ein demokratisches Mitbestimmungsrecht erlangen wollen. Doch wie erfolgreich können solche Anti Corporate Campaigns sein? Mit der Verständigungsorientierten Öffentlichkeitsarbeit ist in den 1990er Jahren ein Instrument entwickelt worden, mit dem unter anderem der Verständigungserfolg von Öffentlichkeitsarbeit messbar gemacht werden kann. Anti Corporate Campaigns fallen in den Sonderbereich der Online-Kampagnenkommunikation und zählen somit zu den Werkzeugen der Public Relations. Folglich ist es möglich den Verständigungserfolg von Protestkampagnen mittels der VÖA zu messen. Das Fallbeispiel, das dieser Forschungsarbeit zugrunde liegt, ist die Online – Anti Corporate Campaign der Bürgerinitiative „Pro Linz“ Überparteiliche Plattform gegen die Westring Transitautobahn mitten durch Linz. Mittels einer quantitativen Online-Befragung wurden die User der Website nach verständigungsrelevanten Merkmalen untersucht, um so den Verständigungserfolg der Protestkampagne zu evaluieren. Die Auswertung der Untersuchungsergebnisse erfolgte mit dem statistischen Auswertungsprogramm SPSS. Die Ergebnisse der Untersuchung zeigen, dass die Mehrheit der befragten User verständigungsrelevante Merkmale besitzen. Diejenigen, die über ausreichendes Wissen über die Bürgerinitiative, den Linzer Westring und die Website verfügen, stimmen in ihren Sach- und Werturteilen mit der BI vermehrt überein. Ebenso empfinden diese Personen die Bürgerinitiative häufiger als seriös vertrauenswürdig, als User mit unzureichendem Wissen. Dennoch gelingt es der Anti Corporate Campaign nicht, genügend User zu aktivieren. Das zeigt sich in den Ergebnissen zu dem Merkmal der „aktiven Auseinandersetzung“. Die summative Evaluierung dieses Fallbeispiels ermöglicht, es Vorschläge für eine Verbesserung der Verständigungsqualität aufzuzeigen. Die Umsetzung obliegt allein der Bürgerinitiative „Pro Linz“.
[Das  Gemeindehaus zu Hottingen]
Creators: name: Nieriker, Joseph
name: Meyer, Conrad
Publisher: name: [s.n.]
Year: 1899
Subjects: Zürich

description: Cop. v. J. Nieriker; nach einer Bleistiftzeichnung v. Conrad Meyer 1618-89
description: Handschriftliche Notiz auf der Rückseite des Passepartouts: "Orig. s. Kh Zh [Kunsthaus Zürich], Skizzenbücher C. Meyers"
[Das  Schlösschen Susenberg auf dem Zürichberg]
Creators: name: Bullinger, Johann Balthasar
Publisher: name: [s.n.]
Year: 1800
Subjects: Zürich

description: [anonym]
description: Es handelt sich vermutlich um eine Kopie nach Johann Balthasar Bullingers (1713-1793) Federzeichnung "Das Schlösslein auf dem Zürichberg", vgl. dazu Signatur STF Bullinger, Johann Balthasar V, 71 der Graphischen Sammlung
title: Sido betet
title: Wenn Hip Hop auf Psalmendidaktik trifft
titleType: Other
Creators: name: Spiering-Schomborg, Nele
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 27-31; ISSN: 1018-1539;
[Beim Kreuz]
Creators: name: Meyer, Johann
Publisher: name: [s.n.]
Year: 1710
Subjects: Zürich

description: Ansicht von Hottingen beim Kreuzplatz
description: [Johannes Meyer]
description: Angaben zu Titel, Künstler und Datierung gemäss handschriftlicher Notiz auf der Rückseite des Blattes: "Appenzeller: Beim Kreuz Joh. Meyer del 1710"
title: Menschenrechte und Demokratie begriffliche Unterschiede und Konvergenzen-
Creators: name: Weingessel, Christoph
Year: 2012

description: Diese Arbeit möchte der Frage nachgehen, wie eng die Begriffe Demokratie und Menschenrechte eng miteinander verknüpft sind und ob in der ideengeschichtlichen Entwicklung der beiden Phänomene immer schon ein notwendiger Zusammenhang bestand. Es wird beleuchtet wie dieser Zusammenhang von maßgeblichen politischen Denkern des 18. Jahrhunderts, in dem sich mit der französischen Revolution und der amerikanischen Unabhängigkeitserklärung die Gedanken von Demokratie und Menschenrechten stark politisch manifestierten, gesehen wurde. In der zweiten Hälfte der Arbeit 4 wechselt der/die LeserIn ins ausgehende 20. Jahrhundert wo nach wie vor dieser Zusammenhang Gestand zahlreicher Betrachtung darstellt. Abschließend kommt die Arbeit zu dem Schluss, dass es sich bei Demokratie und Menschenrechten um zwei unterschiedliche Phänomene handelt, auch wenn eine Sichtweise, in der alle als freie und gleiche Individuen verstanden werden, häufig zu einem Nebeneinander von beiden führen wird.
title: Von stillen Stürmen und stillen Schülern
title: Mit Jugendlichen das Potenzial biblischer Wundererzählungen entdecken
titleType: Other
Creators: name: Drube, Julia
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 32-39; ISSN: 1018-1539;
[Die  alte Kreuzkirche in Hottingen]
Creators: name: Meyer, Johann
Publisher: name: [s.n.]
Year: 1710
Subjects: Zürich

description: Ansicht von Hottingen mit der alten Kreuzkirche
description: [Johannes Meyer]
description: Angaben zu Künstler und Datierung gemäss handschriftlicher Notiz auf der Rückseite des Blattes: "Appenzeller: Joh. Meyer del 1710"
description: Vermerk auf der Rückseite in brauner Tinte und in Bleistift: "Crütz"
title: Zur Prozessualität der Spirale im Film
Creators: name: Müller, Andreas
Year: 2013

description: Die vorliegende Arbeit geht von Untersuchungen über die Prozessualität der Spirale in unterschiedlichen wissenschaftlichen Disziplinen aus, in Folge muss jener im Bereich der bildenden Kunst ein Auftreten als Zustandsmuster attestiert werden. Die implizite Frage nach der Notwendigkeit eines adäquaten Mediums zur Darstellung der Spirale als zeitlich bedingter Wachstumsform führt schließlich zum Film, und geleitet von Gilles Deleuze und seinen Überlegungen zum Kino werden drei Filme exemplarisch auf Mikro- und Makrostrukturen der Spirale untersucht. Eisensteins „Panzerkreuzer Potemkin“ wird vor allem deshalb zuerst vorgestellt, da Eisenstein selbst behauptet hat, er hätte seinen Film als Spirale konzipiert, was nach eingehender Analyse jedoch widerlegt werden musste. In Hitchcocks „Vertigo“ wird endlich nicht nur die subjektbedingte Spirale, sondern gleich eine gegenläufig kreisende Doppelspirale sichtbar. Darüber hinaus setzt Hitchcock den dimensionalen Konflikt räumlicher und zeitlicher Spiralen auch mit ins Bild. Das Kapitel schließt mit einer Analyse der Filmmusik, des stilistisch vorausgreifenden Vorspanns und den damit verbundenen Lissajous-Figuren. Im dritten Filmabschnitt der Arbeit wird Aronofskys Film „PI“ untersucht, in welchem nicht nur das strukturelle Vorkommen der Spirale belegt, sondern deren Wachstumsform mit Überlegungen aus der Feldtheorie untermauert wird. Ein Fokus des letzten Kapitels liegt mitunter auf Aspekten der Transzendenz im Wechselspiel zwischen dem diegetischen und Realraum.
description: The current work emanates from studies on the processuality of the spiral in different scientific disciplines, and as a result from that it had to be attested its occurrence as a fixed pattern in the area of visual art. The implicit question on the necessity of an adequate medium for depicting the spiral as a temporal induced form of growth finally leads to film, and guided by Gilles Deleuze and his reflections on cinema three films are exemplary being examined on micro- and macrostructures of the spiral. „The Battleship Potemkin“ by Eisenstein is presented first above all, because he claimed the concept for the spiral in his film himself, what could be disproved after detailed analysis. In „Vertigo“ by Hitchcock finally not only the subject induced spiral, but also a contra-rotating double spiral is becoming visible. Furthermore Hitchcock is also able to put the dimensional conflict between spatial and temporal spirals into the picture. The chapter closes with an analysis of the film score, the stylistically anticipated opening credits and with this connected the Lissajous figures. In the third film section of the text „PI“ by Aronofsky is examined, where the structural occurrence of the spiral is not only proven, but its form of growth is underpinned with reflections from the field theory. A focus of the last chapter is set occasionally on aspects of transcendence in the interaction between the diegetic and the real space.
title: Measuring satisfaction with health care in young persons with inflammatory bowel disease -an instrument development and validation study
Creators: name: Sadlo, Andrea
name: Altevers, Julia
name: Peplies, Jenny
name: Kaltz, Birgit
name: Classen, Martin
name: Bauer, Alexandra
name: Koletzko, Sibylle
name: Timmer, Antje
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2014
Subjects: subject: 610

description: Background: Patient satisfaction is a relevant prognostic factor in young persons with chronic disease and may be both age and disease specific. To assess health care quality from the patient's view in young persons with inflammatory bowel disease, an easy to use, valid, reliable and informative specific instrument was needed. Methods: All parts of the study were directed at persons with inflammatory bowel disease aged 15 to 24 (" youth"). A qualitative internet patient survey was used to generate items, complemented by a physician survey and literature search. A 2nd internet survey served to reduce items based on perceived importance and representativeness. Following pilot testing to assess ease of use and face validity, 150 respondents to a postal survey in patients from a paediatric clinical registry were included for validation analyses. Construct validity was assessed by relating summary scores to results from global questions on satisfaction with care using ANOVA. To assess test-retest reliability using intraclass correlation coefficients (ICC),a subset of patients were assessed twice within 3 months. Results: 302 persons with IBD and 55 physicians participated in the item generating internet survey, resulting in 3, 954 statements. After discarding redundancies 256 statements were presented in the 2nd internet survey. Of these, 32 items were retained. The resulting instrument assesses both the perceived relevance (importance) of an item as well as the performance of the care giver for each item for calculation of a summary satisfaction score (range 0 to 1). Sensibility testing showed good acceptance for most items. Construct validity was good, with mean scores of 0.63 (0.50 to 0.76),0.71 (0.69 to 0.74) and 0.81 (0.79 to 0.83) for no, some and good global satisfaction (ANOVA, p < 0.001). Test-retest reliability was satisfactory (ICC 0.6 to 0.7). Conclusions: We developed an easy to use, patient oriented, valid instrument to assess satisfaction with care in young persons with IBD for use in survey research.
Cambridge Bioinformatics Hackathon 2017
Creators: name: Wingett, Steven
name: Ayres, Daniel
name: Bagshaw, Andrew
name: Botta, Marco
name: Brown, Katherine
name: Burge, Sarah
name: Burren, Olly
name: Cortijo, Sandra
name: Dialdestoro, Kevin
name: Gogleva, Anna
name: Hamilton, Russell
name: Fengyuan Hu
name: Kayikci, Melis
name: Krueger, Christel
name: Krueger, Felix
name: Manzano, Raquel
name: Matheson, Louise
name: Nguyen, Thuy
name: Malwina Prater
name: Roushanak Rahmat
name: Rice, Peter
name: Rocheteau, Emma
name: Samarghitean, Crina
name: Markiyan Samborskyy
name: Przemyslaw Stempor
name: Tavares, Hugo
name: Thiecke, Michiel
name: Tumescheit, Charlotte
name: Zorin, Andrey
name: Andrews, Simon
Publisher: name: F1000 Research Limited
Year: 2017

description: For several years the Babraham Bioinformatics department has organised a bi-annual hackathon in which participants set themselves a life sciences-related computational project and then spend two days in a room together working on projects collaboratively, drawing on the expertise available.  Following on from the success of these events, we wanted to extend the hackathon to become a Cambridge-wide initiative in which bioinformaticians and computational biologists from across the city could participate.

The Cambridge Bioinformatics Hackathon took place on the 25-27th September 2017 and was open to students, postdocs and PIs from academic institutions or companies.  The event provided a forum for the generation of innovative science and exchange of ideas and the resulting projects were deposited on GitHub, possibly leading to collaborations involving researchers across the world.
[Milchgütlein]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1800
Subjects: Fachwerkbau
Molkerei

description: Ansicht eines Fachwerkhauses mit Garten
description: [anonym]
description: Auf der Rückseite aufgeklebter Papierstreifen mit handschriftlichen Vermerken in Bleistift: "Laîterie aux petits bains" und "Zürichberg Milchgütlein"
Sonnenfleckenzeichnung Nr. 1254.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.09.1892, erstellt von Alfred Wolfer
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1892

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zugeordnete numerische Werte wurden in einer separat geführten, chronologischen Tabelle erfasst. Unter Umständen sind tabellarisch notierte Werte, die für Protuberanzen mit rot geschrieben wurden, direkt auf der Fleckenzeichnung vermerkt
description: ETH-Bibliothek
Organic semiconductor sensors for detecting airborne chemicals
Creators: name: Bunes, Benjamin R.
Publisher: name: University of Utah
Year: 2018
Subjects: carbon nanotube
chemFET
dielectrophoresis
oligomer
organic semiconductor
sensor

description: Organic semiconductors offer tremendous potential for detecting airborne chemicals. Planar, Ï€-conjugated molecules, such as perelyene diimide derivatives, are especially appealing because they can form nanofibers through self-assembly. Depositing these structures onto a substrate creates a porous network. This network is easily penetrable and offers a large surface area for interaction with the target chemical, leading to enhanced sensitivity when used as a gas sensor. Furthermore, the Ï€-conjugation provides electronic conductivity, which enables the use of these ma- terials as chemiresistors. Finally, because the building blocks are organic molecules, there are virtually limitless structural possibilities; molecules can be engineered to interact with a specific chemical by modifying the side groups. Using these materials, our group has demonstrated vapor-phase detection of explosives, chemical warfare agents, narcotics, and toxic gases at concentrations extending into the low parts per trillion range. While organic semiconductors have many strengths, major barriers have limited their utility to the lab. First, the conductivity is intrinsically low. Oftentimes, it is too low to be read by commercial electronics (picoampere scale). Secondly, because of the random way the nanofibers deposit, device-to-device variation is difficult to control. In this dissertation, we will discuss early-stage work to address these issues. Three strategies were investigated and will be presented: 1) integrating sensor molecules with conductive materials, 2) integrating sensor molecules with conductive devices, and 3) controlled deposition to align the nanofibers across the electrode gap. In the first strategy, we explore the fundamental properties of the sensing material interface with carbon nanotubes. The formation of charge transfer complexes and unexpected charge transfer were observed. Next, sensor molecules were used to gate field effect transistors. The result is a sensitive, selective device compatible with production-scale manufacturing. Finally, we will discuss nanofiber alignment using dielectrophoresis. Removing the randomness from deposition is a potential means to reduce device-to- device variation while increasing the conductivity. These investigations may produce a route from the lab to the real world for sensors based on organic semiconductors.
title: Neutestamentliche Streitgespräche
title: Religionspädagogische Überlegungen zur biblischen Gattung Streitgespräch in der markinischen Überlieferung
titleType: Other
Creators: name: Weiß, Thomas
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 40-46; ISSN: 1018-1539;
Bibel ‒ LeserInnen ‒ Perspektiven: polyphon und fragmentarisch
Creators: name: Schiefer Ferrari, Markus
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 47-57; ISSN: 1018-1539;
Population pharmacokinetics of intravenous acetaminophen (paracetamol) and its metabolites in neonates
Creators: name: Cook, Sarah Fogley
Publisher: name: University of Utah
Year: 2018
Subjects: acetaminophen
drug metabolism
LC-MS/MS
neonates
paracetamol
population pharmacokinetics

description: Pain management is a critical component of neonatal intensive care, not only for ethical reasons, but also because the failure to provide adequate analgesia during early life has been associated with poor outcomes. Intravenous acetaminophen is an attractive option for treatment of neonatal pain; however, there is a lack of consensus regarding optimal dosing guidelines, and safety data are limited. A principal safety concern is acetaminophen-induced hepatotoxicity, which depends highly on drug metabolism. Unfortunately, neonatal pharmacokinetic data for acetaminophen metabolites are scarce. The objective of this dissertation was to explore maturational changes in the pharmacokinetics of intravenous acetaminophen and its metabolites in neonates. This goal was achieved by completion of three major aims that centered on a prospective clinical trial. Neonates with a clinical indication for intravenous analgesia received multiple doses of intravenous acetaminophen, and pharmacokinetic samples were collected throughout a 72-h study period. Aim 1 focused on development and validation of a novel high-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification of acetaminophen and the metabolites derived from acetaminophen glucuronidation, sulfation, and oxidation. Suitability of the assay was demonstrated by analysis of plasma and urine samples from the neonatal pharmacokinetic study. In Aim 2, a population pharmacokinetic model was developed from the parent drug concentration-time data. In extremely preterm to full-term neonates, body weight was the principal predictor of intravenous acetaminophen pharmacokinetics. External evaluation with a dataset from an independent study suggested that these findings should be generalizable to other similar patient populations. Aim 3 focused on development of a parent-metabolite population pharmacokinetic model using the data obtained from the neonatal pharmacokinetic study. As part of model development, an extensive covariate analysis was performed to identify patient characteristics that influenced metabolite pharmacokinetic parameters, with a particular focus on formation clearance of metabolites derived from acetaminophen oxidation. Maturational changes in the fraction of acetaminophen undergoing oxidation were small relative to between-subject variability. Collectively, these results improve understanding of the factors influencing acetaminophen disposition during the neonatal period, and these findings inform appropriate dosing strategies for intravenous acetaminophen in this vulnerable patient population.
Experimental study of xurographic spiral microchannel heat sinks
Creators: name: Thamer, Ali Yasser
Publisher: name: University of Utah
Year: 2018
Subjects: Applied sciences

description: An experimental study was performed to explore the possibility of constructing a spiral microchannel heat sink using a laser-based xurographic technology with double-sided adhesive KaptonÂ® tape, which has a low thermal conductivity. Xurography is a rapid prototyping micromanufacturing technology that, in contrast to expensive and time-consuming traditional microfabrication technologies, enables the fabrication of inexpensive microfluidics devices in a short time frame. A set of three xurographic spiral microchannel heat sinks with different channel length, width, hydraulic diameter, aspect ratio, and number of spirals were fabricated, tested and analyzed. For all test sections, channel depth was determined by the KaptonÂ® tape film thickness, which is approximately 105Âµm. The heat sinks were experimentally tested at different flow rates and heat fluxes.  Four sets of tests were performed on each heat sink. Distilled water, used as the working fluid, entered the test sections at room temperature (~22Â°C). The supplied heat ranged from 25 to 200 W, and the Reynolds number ranged from 200 to 1800. Results showed that the device with the widest channel (3 mm) extracts more heat than those with smaller widths and requires the least amount of driving pressure.  The maximum heat dissipation rate for the devices was approximately 140 W, corresponding to a heat flux of approximately 10 W/cmÂ². The maximum convection coefficient was on the order of 6500 W/mÂ²/K and was achieved in the widest channel device with a corresponding Nusselt number of up to 2.2. Results indicate a thermal performance that is less than desirable.  Performance was adversely affected by the low thermal conductivity KaptonÂ® tape and no enhancement due to secondary flows in the spiral geometry was observed. Comparison with a well-known macroscale curved duct correlation revealed a significant difference between the experimental results and predications.
Quorum sensing and host killing in an insect symbiosis
Creators: name: Chari, Abhishek
Publisher: name: University of Utah
Year: 2018
Subjects: host killing
Quorum sensing
Sodalis praecaptivus
symbiosis

description: Sodalis praecaptivus is a recently isolated, novel bacterium that was isolated from a wound on the hand of a 71-year-old human patient. Phylogenetic analysis and comparative genomics revealed that this organism is closely related to members of the Sodalis-allied clade of insect endosymbiotic bacteria. This thesis deals with two investigations of this bacterium. The first is a study providing a physiological and biochemical characterization of this organism. The second is an analysis of the relationship between quorum sensing, virulence modulation against an insect host and a novel self-regulatory population control phenomenon in S. praecaptivus. It is proposed that using a population density signal to modulate virulence and growth could allow this organism to balance the need for host invasion against the need to maintain an asymptomatic infection of high density within an insect vector. This would allow the insect vector to transmit S. praecaptivus between potential plant and animal hosts without significant loss of fitness and might be a crucial step in the conversion of free living antecedent bacteria to mutualistic symbionts.
[Aussicht von der Klus]
Creators: name: Maurer, Heinrich
Publisher: name: [s.n.]
Year: 1800

description: Ansicht mit dem Zürichsee und den Alpen von der Klus (Adlisberg) aus. Im Vordergrund ist ein Bauernhof abgebildet
description: [Heinrich Murer]
description: Angaben zu Titel und Künstler gemäss handschriftlichem Vermerk auf dem Unterlagenblatt
description: Handschriftliche Notizen auf dem Unterlagenblatt, unterhalb des Bildes, links: "Zürich 628"; rechts: "Zürichberg"
[Küsnacht am Zürichsee]
Creators: name: Meyer, Johann
Publisher: name: [s.n.]
Year: 1670
Subjects: Kanton Zürich
Küsnacht, Kanton Zürich

description: Auf der linken Bildseite, direkt am Zürichsee, ist der Gasthof zur Sonne mit seinem mittelalterlichen Turm erkennbar
description: [Conrad Meyer?]
description: Angaben zu Titel und Künstler gemäss Vermerk in Leonhard Zieglers "Catalogus Schweizerischer Prospecten und Landskarten", S. 197
description: In der Mitte des Blattes Wasserzeichen mit Trauben und Buchstaben "PC"
Your support touches my heart: testing a mediational model of receiving social support, culture, and ambulatory blood pressure
Creators: name: Bowen, Kimberly Suzanne
Publisher: name: University of Utah
Year: 2018
Subjects: Ambulatory Blood Pressure
Culture
Interdependence
Japan
Self-schema
Social support

description: Social support is a reliable predictor of psychological and physical health. However, received social support can result in either improvements or detriments to health depending on contextual processes. The cultural facet of independence-interdependence â€" cultural variations in social orientation and self-schema â€" is a macro level of analysis that may determine when receiving social support results in benefits or costs to health. The current study examined whether solicited and unsolicited received support results in either health improvements or health costs. The study consisted of 148 participants in the United States and Japan who completed a 2-day ambulatory blood pressure and daily diary protocol. Multilevel modeling was used to account for the data dependence across repeated measures as well as to examine both effects of support at the individual and cultural level. Mediational bootstrapping analyses and moderated mediational analyses were used to examine whether changes to self-schema variables mediated the relationship between support and health and whether culture served as moderator of these indirect effects. No consistent evidence was found to support these hypotheses. However, some evidence for cultural differences and for the stress-buffering effects of social support on ABP were observed. Implications are discussed.
[Schloss Knonau]
Creators: name: Meyer, Johann
Publisher: name: [s.n.]
Year: 1670

description: Schloss Knonau mit dem Dorf im Hintergrund
description: Joh. Meyer
description: Handschriftliche Bezeichnung in brauner Feder, oben Mitte: "Konau [i.e. Knonau]"
title: Das Veränderungspotenzial der Bibel
title: Eine doppelte Typologie
titleType: Other
Creators: name: Wunderli, Armin
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 58-65; ISSN: 1018-1539;
Effect of various image reconstruction parameters on pet lesion detection performance
Creators: name: Morey, Alan Michael
Publisher: name: University of Utah
Year: 2018
Subjects: imaging
lesion detection
LROC
positron emission tomography

description: Positron emission tomography (PET) images can be reconstructed using a wide variety of techniques. Two aspects of image reconstruction are addressed in this thesis:  the number of subsets used for the block-iterative ordered-subsets expectation-maximization (OSEM) reconstruction algorithm, and using smaller in-plane pixels. Both of these aspects of PET image reconstruction affect image quality. Although image quality in PET is difficult to quantify, it can be evaluated objectively using task-basked assessments such as lesion detection studies. The objective of this work was to evaluate both the effect of the number of OSEM subsets and pixel size on general oncologic PET lesion detection. Experimental phantom data were taken from the Utah PET Lesion Detection Database Resource, modeling whole-body oncologic 18F-FDG PET imaging of a 92kg patient. The data comprised multiple scans on a Biograph mCT time-of-flight (TOF) scanner, with up to 23 sources modeling lesions (diam. 6-16 mm) distributed throughout the phantom for each scan. Two observer studies were performed as part of this thesis. In the first study, images were reconstructed with maximum-likelihood expectation-maximization (MLEM) and with OSEM using 12 different numbers of subsets (i.e., 2-84 subsets). Localization receiver operating characteristics (LROC) analysis was applied using a mathematical observer. The probability of correct localization (PLOC) and the area under the LROC (ALROC) curve were used as figures-of merit in order to quantify lesion detection performance. The results demonstrated an overall decline in lesion detection performance as the number of subsets increased. This loss of image quality can be controlled using a moderate number of subsets (i.e., 12-14 or fewer). In the second study, images were reconstructed with 2.036 mm and 4.073 mm in-plane pixels. Similar LROC analysis methods were applied to determine lesion detection performance for each pixel size. The results of this study demonstrated that images with ~2 mm pixels provided higher lesion detection performance than those with ~4 mm pixels. The primary drawback of using smaller pixels (i.e. ~2 mm) was a 4-fold increase in reconstruction time and data storage requirements. Overall, this work demonstrated that reconstructing with moderate subsets or with smaller voxel sizes may provide important benefits for general PET cancer imaging.
title: Ermächtigung zum Hören
title: Grundriss einer biblischen Hördidaktik
titleType: Other
Creators: name: Wagerer, Wolfgang
Publisher: name: Karl-Franzens-Universität Graz
Year: 2017

description: Österreichisches Religionspädagogisches Forum; Volume 2017 (25); Issue 2;
  Seitenzahl: 66-73; ISSN: 1018-1539;
DNA packaging and ejection by P22-like bacteriophage
Creators: name: Leavitt, Justin Conrad
Publisher: name: University of Utah
Year: 2018
Subjects: Bacteriophage
P22

description: This work analyzes the DNA translocating mechanisms by the â€œP22-likeâ€ bacteriophages Salmonella enterica phage P22 and Shigella flexneri phage Sf6. DNA packaging into virions during assembly and ejection of the DNA into target cells is examined. To explore DNA packaging, interactions of the terminase proteins (TerS and TerL) and their role in recognizing the correct DNA to be packaged are explored experimentally in vivo.  Evidence was obtained showing that the N-terminal domain of TerS is involved in the recognition of bacteriophage DNA, and the C-terminal domain of TerS likely interacts with TerL. The P22 pac site was shown to be necessary and sufficient to induce DNA packaging. Additionally, the Sf6 pac site was identified and shown to be similar to the P22 pac site. The phenotypes of a pac-null P22 mutant and mutations that alter TerS were analyzed. For the first time, the pac site was shown to be essential for P22 lytic growth. Mutations altering the TerS protein that affect pac site recognition were shown to be located in various locations on the protein. Additionally, a mutation in terL was also identified that allows normal progeny phage production in the absence of a functional pac site. This is the first evidence that TerL can work in conjunction with TerS to enable DNA recognition. In our studies of DNA ejection from the virion, a number of insights were obtained. The tail needle (gp26 protein) is the plug that keeps the DNA inside the complete virion, while the ejection proteins (gp7, gp20, and gp16) are required to deliver the DNA into the cytoplasm after gp26 release. We found that alterations of the C-terminal protein domain at the tip of the tail needle can have a strong affect on the rate at which DNA is released into the host cytoplasm, indicating that it may serve as a secondary switch controlling DNA delivery. We also examined the numbers and locations of the three different ejection proteins present in the complete P22 virion and found that they occupy space that is also available to the DNA inside the viral head.