cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Einfluss des Lösungsmittels auf die Wirkstoffbeladung von Mikroreservoirs mittels Inkjet-Printing
Creators: name: Mau, Robert
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 000 Generalities, Science
subject: 610 Medical sciences Medicine
subject: 620 Engineering & allied operations

description: Die Arbeit liefert Erkenntnisse für die Beladung von Reservoirs (Ø 100 µm, Ø 400 µm) mit pharmazeutischen Wirkstoffen mittels Inkjet-Printing. Eine präzise Tropfeneinbringung führt nicht zwangsläufig zu einer präzisen Wirkstoffeinbringung. Während der Lösungsmittelverdunstung treten der Coffee-Ring-Effekt und Creeping auf. Die Ausprägung hängt vom Lösungsmittel ab. Eine leichtflüchtige, ethanolbasierte ASS-Lösung ist stark betroffen, Präzision und Homogenität stark eingeschränkt. Eine sehr schwerflüchtige DMSO-basierte ASS-Lösung ist geringfügig betroffen, Präzision und Homogenität brauchbar.
Development of thermodynamic methods for quantification and understanding of non-covalent interactions in molecular and ionic systems
Creators: name: Kondratev, Stanislav
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 540 Chemistry & allied sciences

description: Dispersion and non-covalent interactions are often responsible for the intramolecular stabilization of flexible or strained molecules, so taking these forces into account is a crucial contribution to rationalizing the unexpected stabilities of such molecules. To quantify non-covalent interactions in such well-defined molecular and ionic systems, we have developed and validated three thermodynamic methods based on the “experimental” enthalpy of vaporization and enthalpy of formation as well as based on the “theoretical” DFT-calculated energy.
Flexible use of electricity in heat-only district heating plants
Creators: name: Trømborg, Erik
name: Havskjold, Monica
name: Bolkesjø, Torjus Folsland
name: Kirkerud, Jon Gustav
name: Tveten, Åsa Grytli
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2017

description: European energy systems are in a period of significant transition, with the increasing shares of variable renewable energy (VRE) and less flexible fossil-based generation units as predominant factors. The supply-side changes are expected to cause large short-term electricity price volatility. More frequent periods of low electricity prices may mean that electric use in flexible heating systems will become more profitable, and such flexible heating systems may, in turn, improve the integration of increasing shares of VRE. The objective of this study is to analyze the likely future of Nordic electricity price levels and variations and how the expected prices might affect the use of electricity and thermal storage in heat-only district heating plants. We apply the North European energy market model Balmorel to provide scenarios for future hourly electricity prices in years with normal, high, and low inflow levels to the hydro power system. The simulation tool energyPRO is subsequently applied to quantify how these electricity price scenarios affect the hourly use of thermal storage and individual boilers in heat-only district heating plants located in Norway. The two studied example plants use wood chips or heat pump as base load representing common technologies for district heating in Norway. The Balmorel results show that annual differences in inflow is still a decisive factor for Norwegian and Nordic electricity prices in year 2030 and that short-term (daily) price variability is expected to increase. In the plant-level simulations, we find that tank storage, which is currently installed in only a few district heating plants in Norway, is a profitable flexibility option that will significantly reduce the use of fossil peak load in both biomass and heat-pump-based systems. Installation of an electric boiler in addition to tank storage is profitable in the heat pump system due to the limited capacity of the heat pump. Electricity will hence, to a large extent, replace gas when heat demand exceeds the capacity of the heat pump. For the bio-based plant, we find that an electric boiler in addition to tank storage is not profitable in the normal electricity price scenario. The electric boiler investments are only profitable when electricity prices are as low as in the high inflow scenario. In that case the electric boiler will provide 17% of the heat supply in the example plant. Fuel prices for peak load and electricity grid tariffs are found to be decisive factors for the electricity use – and therefore flexibility options – provided by heat-only district heating plants.
description: International Journal of Sustainable Energy Planning and Management, Vol 12 (2017)
Suburban Housing Development and Off-Grid Electric Power Supply Assessment for North-Central Nigeria
Creators: name: Ogundari, Ibikunle Olalekan
name: Akinwale, Yusuf Opeyemi
name: Adepoju, Adeyemi Oluseun
name: Atoyebi, Musiliyu Kunle
name: Akarakiri, Joshua Babatunde
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2017

description: Energy infrastructures in North-Central Nigeria are inadequate and grid electricity is unable to meet suburban housing electricity demand. The alternative power-supply options proposed by government for the region require appropriation analysis for selection. Four public housing estates in suburban Abuja are selected for electricity demand analysis under conventional and energy-efficient lighting scenarios; then techno-economic parameters of two off-grid electric power supply systems (PV and Diesel-powered generation) to meet these electricity demands are evaluated. An energy techno-economic assessment methodology is used. The study determines the energy-efficient lighting system is appropriate with 40% energy savings relative to the Conventional Lighting Systems. The diesel generator alternative power-supply option has Life Cycle Costs almost 4 times those of the PV option. The study established the PV-energy-efficient lighting system as the most feasible off-grid electric power supply alternative for implementation.
description: International Journal of Sustainable Energy Planning and Management, Vol 12 (2017)
Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS)
Creators: name: Fay, James M.
name: Dokholyan, Nikolay V.
name: Redler, Rachel L.
name: Caplow, Michael
name: Fee, Lanette
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Soluble misfolded Cu/Zn superoxide dismutase (SOD1) is implicated in motor neuron death in amyotrophic lateral sclerosis (ALS); however, the relative toxicities of the various non-native species formed by SOD1 as it misfolds and aggregates are unknown. Here, we demonstrate that early stages of SOD1 aggregation involve the formation of soluble oligomers that contain an epitope specific to disease-relevant misfolded SOD1; this epitope, recognized by the C4F6 antibody, has been proposed as a marker of toxic species. Formation of potentially toxic oligomers is likely to be exacerbated by an oxidizing cellular environment, as evidenced by increased oligomerization propensity and C4F6 reactivity when oxidative modification by glutathione is present at Cys-111. These findings suggest that soluble non-native SOD1 oligomers, rather than native-like dimers or monomers, share structural similarity to pathogenic misfolded species found in ALS patients and therefore represent potential cytotoxic agents and therapeutic targets in ALS.
SAMUTER Agrosistema de la uva pasa en la comarca de la Axarquía (Málaga)
Creators: name: Pérez, Rocío Silva
name: Romero, Gema González
Publisher: name: Zenodo
Year: 2023
Subjects: SAMUTER, Sistemas Agroalimentarios, Axarquía

description: La ganadería en extensivo de las Montañas de León: el caso de la Reserva de la Biosfera de Ancares leoneses, forma parte del proyecto SAMUTER (Sistemas Agroalimentarios Multifuncionales y Territorializados) (https://samuter.paisajeterritoriouam.es/). La comarca de la Axarquía (Málaga) es un área montañosa del traspaís de uno de los principales enclaves turísticos internacionales (la Costa del Sol) que se sitúa, además, junto a la aglomeración urbana de Málaga, la quinta en importancia demográfica del país. El sistema tejido en torno a la uva de pasa cumple con los requerimientos exigidos a sistemas agroalimentarios territorializados. La literatura especializada incluye a los viñedos entre los sistema agrarios de alto valor natural; ello implica un reconocimiento a su papel en el mantenimiento de la biodiversidad. La proximidad física de viñedos, paseros y bodegas refuerza las condiciones de sostenibilidad y facilita los contactos (físicos y culturales). Viñas, paseros y bodegas impregnan el carácter de estos paisajes, sientan sus raíces identitarias y desempeña un papel ambiental de primer orden. Extensive livestock farming in the Mountains of León: the case of the Biosphere Reserve of Ancares in León is part of the SAMUTER project (Multifunctional and Territorialised Agri-food Systems) (https://samuter.paisajeterritoriouam.es/). The Axarquia region (Malaga) is a mountainous area in the back country of one of the main international tourist enclaves (the Costa del Sol) which is also located next to the urban agglomeration of Malaga, the fifth most important demographic area in the country. The system woven around the sultana grape meets the requirements demanded of territorialised agri-food systems. The specialised literature includes vineyards among the agricultural systems of high natural value; this implies recognition of their role in the maintenance of biodiversity. The physical proximity of vineyards, grazing land and wineries reinforces the conditions for sustainability and facilitates (physical and cultural) contacts. Vineyards, grazing land and wine cellars imbue the character of these landscapes, establish their identity roots and play a major environmental role.
Development of 3d metal catalysts for redox reactions
Creators: name: Leonard, David
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 500 Natural sciences
subject: 540 Chemistry & allied sciences

description: Herein is reported the application of non-noble metal-based catalytic systems for the homogeneous oxidation of organic substrates using air, specifically in amines and N-heterocycles. Simple 3d metal salts have been used, in combination with N-ligands, to facilitate the oxidative cleavage of C(sp3)–C(sp3) bonds. These reactions have been studied, using spectroscopic methods, to propose plausible mechanistic pathways. We believe such deconstructive strategies can enable late-stage functionalisation of pharmaceuticals and the synthesis of drug metabolites.
Calculating the many-potential vacuum polarization density of the Dirac equation in the finite-basis approximation
Creators: name: Salman, Maen
name: Saue, Trond
Publisher: name: arXiv
Year: 2023
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work, we propose an efficient and accurate computational method to evaluate the many-potential $α\left(Zα\right)^{n\ge3}$ vacuum polarization density of hydrogen-like atoms within the finite-basis approximation of the Dirac equation. To prove the performance of our computational method, we choose to work with the one-electron $_{\,\,\,92}^{238}\text{U}$ atom. In summary, we find that compliance with charge conjugation symmetry is a priori required to obtain physical results that are in line with our knowledge of the analytical problem. We also note that the final numerical results are found to be in excellent agreement with previous formal analytical (and numerical) evaluations that are limited to a few simple nuclear distribution models. Our technique can be efficiently implemented and evaluated in codes that solve the radial Dirac equation in the finite basis set framework and allows the use of arbitrary (radial) nuclear charge distribution. The obtained numerical results of the non-perturbative vacuum polarization density automatically account for the extended nuclear size effect. This method is hence of special importance for atomic Dirac problems whose analytical Green's functions expressions are not at hand or have relatively complicated analytical forms. Furthermore, we propose a vacuum polarization density formula that forces compliance with charge conjugation symmetry and can be used in cases where the relativistic basis violates this symmetry, as is the case in most relativistic basis set programs. In addition, we have shown that vector components of the vacuum polarization four-current vanish in the case where the Dirac Hamiltonian is symmetric under time-reversal symmetry.
description: 14 page, 12 figures
Investigation of the impact of three different reference particulate matter on human monocytic THP-1 and lung epithelial A549 cells
Creators: name: Cao, Xin
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 540 Chemistry & allied sciences

description: Air pollution has been one of the biggest environmental issues in the world. Particulate matter (PM) is a very important component of air pollutants. In this thesis, we firstly found PM, collected from different districts, contained diverse PAHs, and exhibited different toxic and mutagenic equivalent. To understand how PM from different sources impact cells and which components play a key role in the observed adverse effects, in vitro experiments on distinct cell types were conducted.
(100610) George Ashmead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: The role of Ductus Venosus colour Doppler in the evaluation of fetal well being
Creators: name: Pai, Vivek
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Outcomes
subject: Obstetrics
subject: Foetus
subject: Statistics
subject: Ultrasound-Spectral Doppler
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Management
subject: Foetal imaging
subject: Cardiovascular system

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: INTRODUCTION Prediction of intrauterine growth restriction (IUGR) is one of the most challenging areas of research. It is considered a major contributor of perinatal morbidity and mortality. In spite of better methods of prediction using...
A Coalitional Game for Distributed Inference in Sensor Networks with Dependent Observations
Creators: name: He, Hao
name: Varshney, Pramod K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: We consider the problem of collaborative inference in a sensor network with heterogeneous and statistically dependent sensor observations. Each sensor aims to maximize its inference performance by forming a coalition with other sensors and sharing information within the coalition. It is proved that the inference performance is a nondecreasing function of the coalition size. However, in an energy constrained network, the energy consumption of inter-sensor communication also increases with increasing coalition size, which discourages the formation of the grand coalition (the set of all sensors). In this paper, the formation of non-overlapping coalitions with statistically dependent sensors is investigated under a specific communication constraint. We apply a game theoretical approach to fully explore and utilize the information contained in the spatial dependence among sensors to maximize individual sensor performance. Before formulating the distributed inference problem as a coalition formation game, we first quantify the gain and loss in forming a coalition by introducing the concepts of diversity gain and redundancy loss for both estimation and detection problems. These definitions, enabled by the statistical theory of copulas, allow us to characterize the influence of statistical dependence among sensor observations on inference performance. An iterative algorithm based on merge-and-split operations is proposed for the solution and the stability of the proposed algorithm is analyzed. Numerical results are provided to demonstrate the superiority of our proposed game theoretical approach.
Innate behavioural response of Symsagittifera roscoffensis to selected environmental conditions
Angeborene Verhaltensreaktion von Symsagittifera roscoffensis unter gewählten Umweltbedingungen
Creators: name: Janßen, Marjan
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 500 Natural sciences
subject: 570 Life science

description: The sandy eulittoral of the west coast of Europe is the habitat of the green worm Symsagittifera roscoffensis. It’s green colour results from an endosymbiosis with the micro algae Tetraselmis convolutae. The availability of light and nutrients plays a fundamental role for both partners. This theses elucidates the behaviour of the host S. roscoffensis under different light conditions and its ability to react to nutrients. S. roscoffensis chooses optimal light conditions for its symbiont and buries itself into the sand at high light intensities and protects its symbiont against photo damage.
title: Does collimation affect patient dose in antero-posterior thoraco-lumbar spine?
Creators: name: Hogg, Peter
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Dosimetric comparison
subject: Dosimetry
subject: Diagnostic procedure
subject: Digital radiography
subject: Musculoskeletal spine

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To reduce ionising radiation dose in radiography, whilst at the same time achieving images of optimum quality Specific focus is to determine whether differences in organ dose, effective dose and effective risk of cancer incidence for a range of ages...
Phosphorylation at Y1065 in Vinculin Mediates Actin Bundling, Cell Spreading, and Mechanical Responses to Force
Creators: name: Thompson, Peter M.
name: Tolbert, Caitlin E.
name: Superfine, Richard
name: Burridge, Keith
name: Campbell, Sharon L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Vinculin is an essential structural adaptor protein that localizes to sites of adhesion and is involved in a number of cell processes including adhesion, spreading, motility, force transduction, and cell survival. The C-terminal vinculin tail domain (Vt) contains the necessary structural components to bind and cross-link actin filaments. Actin binding to Vt induces a conformational change that promotes dimerization through the C-terminal hairpin of Vt and enables actin filament cross-linking. Here we show that Src phosphorylation of Y1065 within the C-terminal hairpin regulates Vt-mediated actin bundling and provide a detailed characterization of Y1065 mutations. Furthermore, we show that phosphorylation at Y1065 plays a role in cell spreading and the response to the application of mechanical force.
Ribosome RNA Assembly Intermediates Visualized in Living Cells
Creators: name: McGinnis, Jennifer L.
name: Weeks, Kevin M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: In cells, RNAs likely adopt numerous intermediate conformations prior to formation of functional RNA-protein complexes. We used single-nucleotide resolution selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE) to probe the structure of Escherichia coli 16S rRNA in healthy growing bacteria. SHAPE-directed modeling indicated that the predominant steady-state RNA conformational ensemble in dividing cells had a base-paired structure different from that expected on the basis of comparative sequence analysis and high-resolution studies of the 30S ribosomal subunit. We identified the major cause of these differences by stopping ongoing in-cell transcription (in essence, an in-cell RNA structure pulse-chase experiment) which caused the RNA to chase into a structure that closely resembled the expected one. Most helices that formed alternate RNA conformations under growth conditions interact directly with tertiary-binding ribosomal proteins and form a C-shape that surrounds the mRNA channel and decoding site. These in-cell experiments lead to a model in which ribosome assembly factors function as molecular struts to preorganize this intermediate and emphasize that the final stages of ribonucleoprotein assembly involve extensive protein-facilitated RNA conformational changes.
NLO Higgs Effective Field Theory and kappa-framework
Creators: name: Ghezzi, Margherita
name: Gomez-Ambrosio, Raquel
name: Passarino, Giampiero
name: Uccirati, Sandro
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A consistent framework for studying Standard Model deviations is developed. It assumes that New Physics becomes relevant at some scale beyond the present experimental reach and uses the Effective Field Theory approach by adding higher-dimensional operators to the Standard Model Lagrangian and by computing relevant processes at the next-to-leading order, extending the original kappa-framework.
description: 33 pages + appendices
A Sun-like star orbiting a boson star
Creators: name: Pombo, Alexandre M.
name: Saltas, Ippocratis D.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The high-precision astrometric mission GAIA recently reported the remarkable discovery of a Sun-like star closely orbiting a dark object, with a semi-major axis and period of $1.4\, \rm{AU}$ and $187.8$ days respectively. While the plausible expectation for the central dark object is a black hole, the evolutionary mechanism leading to the formation of such a two-body system is highly challenging. Here, we challenge the scenario of a central black hole and show that the observed orbital dynamics can be explained under fairly general assumptions if the central dark object is a stable clump of bosonic particles of spin-0, or spin-1, known as a boson star. We further explain how future astrometric measurements of similar systems will provide an exciting opportunity to probe the fundamental nature of compact objects and test compact alternatives to black holes.
description: 11 pages, 4 figures. Comments are very welcome
Verankerungsstabilität und periimplantäre Knochendichte von Kurzschaftendoprothesen
Creators: name: Steens, Wolfram
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 610 Medical sciences Medicine

description: Das Ziel dieser Arbeit war es zu evaluieren, inwieweit Kurzschaftkonzepte eine Alternative zu herkömmlichen Standardschäften hinsichtlich Implantatstabilität, funktionell- radiologischem Ergebnis sowie periprothetischem Knochenumbau darstellen. Kurzschäfte zeigen Migrationsmuster, die als frühe postoperative Mikrobewegung mit anschließender kontinuierlicher Stabilität beschrieben werden können. Kurzschäfte können den Standardschäften vergleichbare klinische Ergebnisse liefern. Schenkelhalserhaltende Konstruktionen weisen hinsichtlich des Implantatüberlebens schlechtere Ergebnisse auf.
(100611) William Alexander Garraway
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
RNA Tertiary Structure Analysis by 2′-Hydroxyl Molecular Interference
Creators: name: Tandon, Arpit
name: Dokholyan, Nikolay V.
name: Ding, Feng
name: Weeks, Kevin M.
name: Homan, Philip J.
name: Rice, Greggory M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: We introduce a melded chemical and computational approach for probing and modeling higher-order intramolecular tertiary interactions in RNA. 2'-Hydroxyl molecular interference (HMX) identifies nucleotides in highly packed regions of an RNA by exploiting the ability of bulky adducts at the 2'-hydroxyl position to disrupt overall RNA structure. HMX was found to be exceptionally selective for quantitative detection of higher-order and tertiary interactions. When incorporated as experimental constraints in discrete molecular dynamics simulations, HMX information yielded accurate three-dimensional models, emphasizing the power of molecular interference to guide RNA tertiary structure analysis and fold refinement. In the case of a large, multidomain RNA, the Tetrahymena group I intron, HMX identified multiple distinct sets of tertiary structure interaction groups in a single, concise experiment.
Modellierung und Optimierung von Energiespeichern in Kraft-Wärme-Kopplungsanlagen
Creators: name: Haupt, Axel
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 600 Technology (Applied sciences)
subject: 620 Engineering & allied operations

description: In dieser Arbeit wurde das Zusammenspiel von wärmegeführten Kraft-Wärme-Kopplung-Anlagen (kurz: KWK-Anlagen) für Ein- und Mehrfamilienhäuser mit verschiedenen elektrischen Energiespeichern simuliert und evaluiert. Neben dem Vergleich verschiedener KWK-Systeme und elektrischer Energiespeicher wurde auch die Untersuchungsmethode an sich mittels stochastischer Verfahren, wie der Monte-Carlo-Methode, evaluiert und auf ihre Aussagegenauigkeit hin getestet. Somit können mit dieser Arbeit geeignete Speichertechnologien für wärmegeführte KWK-Anlagen identifiziert und ausgelegt werden.
SAMUTER Los viñedos de La Mancha
Creators: name: Pulpón, Ángel Raúl Ruiz
name: Ruiz, María Del Carmen Cañizares
Publisher: name: Zenodo
Year: 2023
Subjects: SAMUTER, Sistema agroalimentario, La Mancha

description: Los Viñedos de La Mancha forman parte del proyecto SAMUTER (Sistemas Agroalimentarios Multifuncionales y Territorializados) (https://samuter.paisajeterritoriouam.es/). El SAMUTER analiza las interrelaciones entre las condiciones naturales y humanas del territorio donde se extienden los viñedos de la comarca de La Mancha, dentro de la región de Castilla-La Mancha (España). The Vineyards of La Mancha are part of the SAMUTER project (Multifunctional and Territorialised Agri-Food Systems) (https://samuter.paisajeterritoriouam.es/). SAMUTER analyses the interrelationships between the natural and human conditions of the territory where the vineyards of the La Mancha region of Castilla-La Mancha (Spain) are located.
Direct numerical simulation of sloshing and phase change in LH2 tanks
Creators: name:  LEANDRO GERMES MARTINEZ
name:   BENJAMIN DURET
name:   JULIEN REVEILLON
name:   FRANCOIS-XAVIER DEMOULIN
name:   AMAURIC JARRY
Publisher: name: Proceedings of the Aerospace Europe Conference - EUCASS - CEAS - 2023
Year: 2023
Subjects: DIRECT NUMERICAL SIMULATION
SLOSHING
PHASE CHANGE
INTERFACE RESOLUTION
HYDROGEN

description: Better understanding the boil-off phenomenon is necessary to optimize the storage and transportation of cryogenic liquids, especially during space missions where the cryogenic tank is subjected to various stresses. Here, a numerical study of sloshing and boiling in LH2 tanks using direct numerical simulation is presented. A compressible formalism is retained to capture phase change and interface deformation in a confined two-phase environment. Our objective is to analyze the behavior of the boil off rate in a sloshed cryogenic tank. A significant increase of the boiling rate is observed compared to the static configuration with the same parameters.
The quest for Magrathea planets I: formation of second generation exoplanets around double white dwarfs
Creators: name: Ledda, S.
name: Danielski, C.
name: Turrini, D.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The evolution of binaries that become double white dwarf (DWD) can cause the ejection of high amounts of dust and gas. Such material can give rise to circumbinary discs and become the cradle of new planets, yet no studies so far have focused on the formation of circumbinary planets around DWDs. These binaries will be the main sources of gravitational waves (GWs) detectable by the ESA Laser Interferometer Space Antenna (LISA) mission, opening the possibility to detect circumbinary planets around short-period DWDs everywhere in the Milky Way. We investigate the formation of Magrathea planets by simulating multiple planet formation tracks to explore how seeds growing first by pebble accretion, and then by gas accretion, are affected by the disc environments surrounding DWDs. We present both planetary formation tracks taking place in steady-state discs, and formation tracks taking place in discs evolving with time. The time-dependent tracks account for both the disc accretion rate onto the central binary and the disc photoevaporation rate caused by stellar irradiation. Our results show that planetary formation in circumbinary discs around DWDs can be possible. In particular, the extreme planetary formation environment implies three main significant results: (i) the accretion rate and the metallicity of the disc should be high in order to form sub-stellar objects with masses up to 31 M$_J$, this is achieved only if planet formation starts soon after the onset of the disc and if first generation seeds are present in the disc; (ii) seeds formed within 0.1 Myr, or within 1 Myr, from the onset of the disc can only produce sub-Neptune and Neptunian planets, unless the disc accommodates first generation seeds with mass 10 M$_{\oplus}$; (iii) most of the planets are finally located within 1 au from the disc centre, while they are still undergoing the gas accretion phase.
description: Accepted for publication in A&A on 05/04/2023, abstract shortened, 28 pages, 11 figures, 14 tables
title: Determination of gestational age by measuring the fetal kidney length after the 20th week of gestation and its significance in Intrauterine Growth Restriction (IUGR) with correlation to fetal renal doppler
Creators: name: Pai, Vivek
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Foetus
subject: Intrauterine diagnosis
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Paediatric
subject: Obstetrics (Pregnancy / birth / postnatal period)
subject: Foetal imaging
subject: Obstetrics

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: 1. To determine the correlation between the length of the fetal kidney and its gestational age (determined ultrasonically using standard growth parameters) in pregnancies beyond the 20th week. . 2. To determine the changes in the fetal kidney length...
Current-induced bond rupture in single-molecule junctions: Effects of multiple electronic states and vibrational modes
Creators: name: Ke, Yaling
name: Dvořák, Jan
name: Čížek, Martin
name: Borrelli, Raffaele
name: Thoss, Michael
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Current-induced bond rupture is a fundamental process in nanoelectronic architectures such as molecular junctions and in scanning tunneling microscopy measurements of molecules at surfaces. The understanding of the underlying mechanisms is important for the design of molecular junctions that are stable at higher bias voltages and is a prerequisite for further developments in the field of current-induced chemistry. In this work, we analyse the mechanisms of current-induced bond rupture employing a recently developed method, which combines the hierarchical equations of motion approach in twin space with the matrix product state formalism, and allows accurate, fully quantum mechanical simulations of the complex bond rupture dynamics. Extending previous work [J. Chem. Phys. 154, 234702 (2021)], we consider specifically the effect of multiple electronic states and multiple vibrational modes. The results obtained for a series of models of increasing complexity show the importance of vibronic coupling between different electronic states of the charged molecule, which can enhance the dissociation rate at low bias voltages profoundly.
Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae
Creators: name: Nicholas, Robert A.
name: Fedarovich, Alena
name: Davies, Christopher
name: Tomberg, Joshua
name: Cook, Edward
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: A hallmark of penicillin-binding protein 2 (PBP2) from penicillin-resistant strains of Neisseria gonorrhoeae is insertion of an aspartate after position 345. The insertion resides on a loop near the active site and is immediately adjacent to an existing aspartate (Asp346) that forms a functionally important hydrogen bond with Ser363 of the SxN conserved motif. Insertion of other amino acids, including Glu and Asn, can also lower the rate of acylation by penicillin, but these insertions abolish transpeptidase function. Although the kinetic consequences of the Asp insertion are well-established, how it impacts the structure of PBP2 is unknown. Here, we report the 2.2 Å resolution crystal structure of a truncated construct of PBP2 containing all five mutations present in PBP2 from the penicillin-resistant strain 6140, including the Asp insertion. Commensurate with the strict specificity for the Asp insertion over similar amino acids, the insertion does not cause disordering of the structure, but rather induces localized flexibility in the β2c−β2d loop. The crystal structure resolves the ambiguity of whether the insertion is Asp345a or Asp346a (due to the adjacent Asp) because the hydrogen bond between Asp346 and Ser362 is preserved and the insertion is therefore Asp346a. The side chain of Asp346a projects directly toward the β-lactam-binding site near Asn364 of the SxN motif. The Asp insertion may lower the rate of acylation by sterically impeding binding of the antibiotic or by hindering breakage of the β-lactam ring during acylation because of the negative charge of its side chain.
Statistical perspectives on dependencies between genomic markers
Creators: name: Wittenburg, Dörte
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 570 Life science
subject: 630 Agriculture

description: To study the genetic impact on a quantitative trait, molecular markers are used as predictor variables in a statistical model. This habilitation thesis elucidated challenges accompanied with such investigations. First, the usefulness of including different kinds of genetic effects, which can be additive or non-additive, was verified. Second, dependencies between markers caused by their proximity on the genome were studied in populations with family stratification. The resulting covariance matrix deserved special attention due to its multi-functionality in several fields of genomic evaluations.
Experimental Scattershot Boson Sampling
Creators: name: Bentivegna, Marco
name: Spagnolo, Nicolò
name: Vitelli, Chiara
name: Flamini, Fulvio
name: Viggianiello, Niko
name: Latmiral, Ludovico
name: Mataloni, Paolo
name: Brod, Daniel J.
name: Galvão, Ernesto F.
name: Crespi, Andrea
name: Ramponi, Roberta
name: Osellame, Roberto
name: Sciarrino, Fabio
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Boson Sampling is a computational task strongly believed to be hard for classical computers, but efficiently solvable by orchestrated bosonic interference in a specialised quantum computer. Current experimental schemes, however, are still insufficient for a convincing demonstration of the advantage of quantum over classical computation. A new variation of this task, Scattershot Boson Sampling, leads to an exponential increase in speed of the quantum device, using a larger number of photon sources based on parametric downconversion. This is achieved by having multiple heralded single photons being sent, shot by shot, into different random input ports of the interferometer. Here we report the first Scattershot Boson Sampling experiments, where six different photon-pair sources are coupled to integrated photonic circuits. We employ recently proposed statistical tools to analyse our experimental data, providing strong evidence that our photonic quantum simulator works as expected. This approach represents an important leap toward a convincing experimental demonstration of the quantum computational supremacy.
description: 8 pages, 5 figures (plus Supplementary Materials, 14 pages, 8 figures)
title: Recognition of Shariah family law in the UK: assessing the application of Shariah succession within Scots law in theory and practice
Creators: name: Alkhamis, Ahmad Mohammad
Publisher: name: University of Glasgow
Year: 2023

description: The practice of Shariah family law has been growing in the UK over the last few decades. This growth in practice has encountered a slow pace of recognition within the existing legal systems, which means that Muslims living in non-Muslim countries who wish to follow Shariah family law in their personal affairs, including marriage, divorce and succession, may face some obstacles in their ability to pursue these practices. This thesis seeks to clarify Shariah family law practices among Muslims and their recognition within the legal systems of England and Scotland. More precisely, this thesis concentrates on investigating the practice of Shariah succession among Scottish Muslims and its applicability to Scots law. This research utilises mixed doctrinal and empirical methods in examining the research issues. The first part of the thesis conceptualises the broad acceptance of Shariah law in Europe. It begins by examining in context how Shariah law practices are tolerated within the scope of multiculturalism. Subsequently, it moves to examine the process whereby the European Convention on Human Rights may lean more toward restricting Shariah practice, unlike Christian practices, because of the influence of Christianity in shaping modern human rights law. It examines a recent case in Shariah succession practice which may show some flexibility in the accommodation of Shariah family law practices. The second part of the thesis assesses the practice of Shariah family law within domestic and private international law. This assessment demonstrates how failure to recognise Islamic marriages and divorces in the UK impacts on the practice of succession. The last part of the thesis examines the perception of Shariah succession practice among Muslims in Scotland. An empirical approach was adopted because of the lack of case law and secondary literature in this area. It argues that despite the potential conflicts between Shariah and Scots law, an Islamic will could be applied within the framework of Scots law. However, it concludes that intestacy law may not be feasibly applied without the consent of all of the beneficiaries of the deceased’s estate. This thesis concludes that while Muslim heirs could maintain the rights assigned by forced heirship rules in Shariah law, other factors might hinder their wishes to apply those rules. This could be due to the amount and type of assets the deceased may leave, whereby applying the forced heirship rules may not satisfy the inheritance rules of Scots law.
(100612) John Stubbings Ashmead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Improved imbalanced classification through convex space learning
Creators: name: Bej, Saptarshi
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 000 Generalities, Science
subject: 004 Data processing Computer sciences

description: Imbalanced datasets for classification problems, characterised by unequal distribution of samples, are abundant in practical scenarios. Oversampling algorithms generate synthetic data to enrich classification performance for such datasets. In this thesis, I discuss two algorithms LoRAS & ProWRAS, improving on the state-of-the-art as shown through rigorous benchmarking on publicly available datasets. A biological application for detection of rare cell-types from single-cell transcriptomics data is also discussed. The thesis also provides a better theoretical understanding behind oversampling.
null Effekt von resistenter Maisstärke, Laktulose und L. casei auf die Ammoniakentgiftung im Kolon, die orozökale Transitzeit sowie die Wasserstoff und Methanbildung, gemessen anhand der Metabolisierung von Laktose [13C]ureid und Laktose [15N2]ureid beim Menschen
Creators: name: Frank, Patricia
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 500 Natural sciences
subject: 610 Medical sciences Medicine

description: In der Studie nahmen 25 gesunde Erwachsene 10 Tage je Maisstärke, Laktulose und L. casei- Joghurt in unterschiedlicher Reihenfolge ein. Zu Studienbeginn und nach den Supplementationsphasen schloss sich eine Messung an. Hierbei wurden als Tracersubstanzen Laktose-[13C]ureid und Laktose-[15N2]ureid eingesetzt. Anschließend wurden in Atemgasproben die Methan- und Wasserstoffkonzentration, die 13C-Exkretion sowie die orozökale Transitzeit ermittelt. In Urin- und Stuhlproben wurden die 13C-und 15N-Exkretion, 15N-Ammoniak- und die Stickstoffkonzentration ermittelt.
Structure and Dynamics of the HIV-1 Frameshift Element RNA
Creators: name: Garcia-Miranda, Pablo
name: Mouzakis, Kathryn D.
name: Butcher, Samuel E.
name: Weeks, Kevin M.
name: Gorelick, Robert J.
name: Low, Justin T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The HIV-1 ribosomal frameshift element is highly structured, regulates translation of all virally encoded enzymes, and is a promising therapeutic target. The prior model for this motif contains two helices separated by a three-nucleotide bulge. Modifications to this model were suggested by SHAPE chemical probing of an entire HIV-1 RNA genome. Novel features of the SHAPE-directed model include alternate helical conformations and a larger, more complex structure. These structural elements also support the presence of a secondary frameshift site within the frameshift domain. Here, we use oligonucleotide-directed structure perturbation, probing in the presence of formamide, and in-virion experiments to examine these models. Our data support a model in which the frameshift domain is anchored by a stable helix outside the conventional domain. Less stable helices within the domain can switch from the SHAPE-predicted to the two-helix conformation. Translational frameshifting assays with frameshift domain mutants support a functional role for the interactions predicted by and specific to the SHAPE-directed model. These results reveal that the HIV-1 frameshift domain is a complex, dynamic structure and underscore the importance of analyzing folding in the context of full-length RNAs.
(100608) Edward Mardon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Microwave signatures of Majorana states in a topological Josephson junction
Creators: name: Väyrynen, Jukka I.
name: Rastelli, Gianluca
name: Belzig, Wolfgang
name: Glazman, Leonid I.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We find the admittance of a topological Josephson junction $Y(ω,φ_0, T)$ as a function of frequency $ω$, the static phase bias $φ_0$ applied to the superconducting leads, and temperature $T$. The dissipative part of $Y$ allows for spectroscopy of the sub-gap states in the junction. The resonant frequencies $ω_{\mathcal{M}, n} (φ_0)$ for transitions involving the Majorana ($\mathcal{M}$) doublet exhibit characteristic kinks in the $φ_0$-dependence at $φ_0=π$. The kinks -- associated with decoupled Majorana states -- remain sharp and the corresponding spectroscopic lines are bright at any temperature, as long as the leads are superconducting. The developed theory may help extracting quantitative information about Majorana states from microwave spectroscopy.
description: 5+16 pages, 2 figures
Klinisches Outcome nach interventioneller Edge-to-Edge-Rekonstruktion der Mitralklappe bei Hochrisikopatienten mit multiplen kardiovaskulären Eingriffen
Creators: name: Albayrak, Neris San
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 610 Medical sciences Medicine

description: In der vorliegenden Arbeit wurde der klinische Verlauf sowie das Langzeitüberleben nach MitraClip-Intervention bei 152 Hochrisikopatientinnen und -patienten mit multiplen kardiologischen Eingriffen dargestellt und prädiktive Faktoren für die Mortalität analysiert.