cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Synthesis and plant growth inhibitory activity of N-trans-cinnamoyltyramine: its possible inhibition mechanisms and biosynthesis pathway
Creators: name: Thi, Ho Le
name: Haiying Zhou
name: Chung-Ho Lin
name: Shengjun Liu
name: Berezin, Mikhail Y.
name: Smeda, Reid J.
name: Fritschi, Felix B.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The search for potent, selective bioherbicides has been the focus of numerous studies for several decades. Developing an economically viable total chemical synthesis procedure has been the challenge for commercial-scale application of these nature-derived chemicals. An efficient and low-cost total synthesis of an allelopathic and antitumor N-trans-cinnamoyltyramine (NTCT) first reported in rice (Oryza sativa L.) was successfully achieved by one-step amidation from trans-cinnamic acid and tyramine. The synthesized NTCT inhibited root and hypocotyl growth of cress (Lepidium sativum L.) and barnyardgrass (Echinochloa crus-galli L.) at concentrations as low as 0.24 μM. The means of ED50 (the effective dose required for 50% plant growth inhibition) levels of the compound on cress and barnyardgrass hypocotyl and root elongations were 0.96 and 0.73 μM, respectively. Potential mechanisms underlying NTCT growth inhibition and its biosynthesis pathway were also suggested. The developed synthesis strategy could permit production of this synthesized allelochemical at a commercial scale as a bioherbicide.
Additional file 1 of Clearing the air: underestimation of youth smoking prevalence associated with proxy-reporting compared to youth self-report
Creators: name: Barrett, Eden M.
name: Maddox, Raglan
name: Thandrayen, Joanne
name: Banks, Emily
name: Lovett, Raymond
name: Heris, Christina
name: Thurber, Katherine A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer

description: Additional file 1.
Additional file 1 of Tranexamic acid alters the immunophenotype of phagocytes after lower limb surgery
Creators: name: Draxler, Dominik F.
name: Hanafi, Gryselda
name: Zahra, Saffanah
name: McCutcheon, Fiona
name: Ho, Heidi
name: Keragala, Charithani B.
name: Liu, Zikou
name: Daly, David
name: Painter, Thomas
name: Wallace, Sophia
name: Plebanski, Magdalena
name: Myles, Paul S.
name: Medcalf, Robert L.
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Supplementary Figure 1. Gating strategy used to identify myeloid cells. Supplementary Figure 2. Gating strategy used to identify B cells. Supplementary Figure 3. Gating strategy used to identify NK cells. Supplementary Figure 4. Comparison of results for TXA-treated patients in the randomised and after the randomised recruitment. Supplementary Figure 5. Plasmin-antiplasmin (PAP) complex as a readout for plasmin generation.
ПРОТИДIЯ МАРНОТРАТНОМУ ВИТРАЧАННЮ ПАЛИВНО-ЕНЕРГЕТИЧНИХ РЕСУРСIВ В УКРАЇНI: АДМIНIСТРАТИВНО-ПРАВОВI АСПЕКТИ
Creators: name: Kramar, Ruslana
Publisher: name: figshare
Year: 2017
Subjects: subject: Law
subject: FOS: Law

description: До уваги читачів пропонується праця, в якій автор досліджує сутності адміністративних правопорушень та відповідальності за марнотратне витрачання плавно-енергетичних ресурсів. Монографія буде корисною фахівцям з адміністративного права, кримінального права, працівникам правоохоронних органів, слухачам юридичних ВНЗ, а також тим, хто цікавиться проблемами правопорушень.
Additional file 2 of Obesogenic and diabetic effects of CD44 in mice are sexually dimorphic and dependent on genetic background
Creators: name: VerHague, Melissa
name: Albright, Jody
name: Barron, Keri
name: Kim, Myungsuk
name: Bennett, Brian J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Biology

description: Additional file 2: Figure S1. Changes in body weight. Wild type (B6 and C3H) and CD44-deficient (CD44.B6 and CD44.C3H) mice were fed a high fat, high sucrose, high cholesterol diet for 12 weeks. A: Changes in body weight (g) were calculated as the difference in final body weight and the initial body weight. Changes in percent lean mass of body weight (B) and percent fat mass of body weight (C) were calculated by the difference between the percentages calculated at the final and initial timepoint. Data are mean ± SE (n = 12–15). Bars labeled with different letters are P
Additional file 1 of Effect of listening to music on anxiety, pain, and cardiorespiratory parameters in cardiac surgery: study protocol for a randomized clinical trial
Creators: name: de Andrade, Érica Vieira
name: Haas, Vanderlei José
name: de Faria, Maíla Fidalgo
name: dos Santos Felix, Márcia Marques
name: Ferreira, Maria Beatriz Guimarães
name: Barichello, Elizabeth
name: da Silva Pires, Patricia
name: Barbosa, Maria Helena
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Additional file 1. SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents. A completed SPIRIT checklist with page numbers next to each item corresponding to where it is found within the protocol.
How to Save the Universe: testable physics from game theory.
Creators: name: Coyle, Dylan
Publisher: name: figshare
Year: 2017
Subjects: subject: 29902 Complex Physical Systems
subject: FOS: Physical sciences
subject: Entropy
subject: Computation Theory and Mathematics
subject: FOS: Computer and information sciences
subject: 20203 Particle Physics

description: 1: A model of the early universe as a Big Game instead of just a Big Bang shows we are the product of countless good choices, not just good luck or fine-tuning.

2: A vector/agent based model of sub-quantum physics shows that new particles in converging systems have a bias towards antimatter and new particles in diverging systems have a bias towards cis-matter. This rules out impending doom from big crunches or big tears.

3: A model of information flow in the universe assumes that information can be destroyed, but by mapping a course out of doomed zones like galaxies, intelligent systems bring compressed information about the doomed zones with them thereby preventing information destruction. This model solves the Fermi paradox; the universe looks like it is ending to agents that can’t make good choices, but looks like an endless series of tests to more intelligent agents. So theory shows that our choices have consequences and the universe won’t end as long as we play the Big Game intelligently.
What Ails Italy: The Competitive Issue of the Italian State
Creators: name: MARTINIS, DOMENICO DE
Publisher: name: figshare
Year: 2017
Subjects: subject: 160511 Research, Science and Technology Policy
subject: FOS: Political science
subject: 160509 Public Administration
subject: 160506 Education Policy

description: Italy faces a most challenging global financial and economic crisis since the end of World War II. For an economy that grew at a rapid pace between the 1950’s and the 1980’s, Italy has seen slower growth in the last twenty years. Italian policymakers are facing a series of problems that include a contracting gross domestic product (GDP), large unemployment, especially among its young people, high government deficits, large governmental borrowing along with high interest rates, and a divisive north-south economy, to name a few. Adding to these dilemmas are its recent recessionary periods, which some liken to a depression, a decrease in domestic demand, and an exodus by highly skilled younger people for better employment prospects in other countries. Italian policymakers are trying diverse solutions to these complex problems, but are worried that they may not be enough to solve its crisis.
Physico-Chemical Alternatives in Lignocellulosic Materials in Relation to the Kind of Component for Fermenting Purposes
Creators: name: Coz, Alberto
name: Llano, Tamara
name: Cifrián, Eva
name: Viguri, Javier
name: Maican, Edmond
name: Sixta, Herbert
Publisher: name: figshare
Year: 2017
Subjects: subject: 90703 Environmental Technologies
subject: FOS: Environmental engineering

description: The complete bioconversion of the carbohydrate fraction is of great importance for a lignocellulosic-based biorefinery. However, due to the structure of the lignocellulosic materials, and depending basically on the main parameters within the pretreatment steps, numerous byproducts are generated and they act as inhibitors in the fermentation operations. In this sense, the impact of inhibitory compounds derived from lignocellulosic materials is one of the major challenges for a sustainable biomass-to-biofuel and -bioproduct industry. In order to inimise the negative effects of these compounds, numerous methodologies have been tested including physical, chemical, and biological processes. The main physical and chemical treatments have been studied in this work in relation to the lignocellulosic material and the inhibitor in order to point out the best mechanisms for fermenting purposes. In addition, special atention has been made in the case of lignocellulosichydrolysates obtained by chemical processes with SO2, due to the complex matrix of these materialsand the increase in these methodologies in future biorefinery markets. Recommendations of different detoxification methods have been given.
Additional file 1 of Antibiotic delivery evaluation against Mycobacterium fortuitum using nanofluids containing carbon nanotubes
Creators: name: Pargami, Hamid Naderi
name: Siadat, Seyed Davar
name: Amiri, Vahid
name: Sheikhpour, Mojgan
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1.
Additional file 1 of Content and comprehensiveness in the nursing documentation for residents in long-term dementia care: a retrospective chart review
Creators: name: Laukvik, Lene Baagøe
name: Lyngstad, Merete
name: Rotegård, Ann Kristin
name: Slettebø, Åshild
name: Fossum, Mariann
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1.
Additional file 2 of Content and comprehensiveness in the nursing documentation for residents in long-term dementia care: a retrospective chart review
Creators: name: Laukvik, Lene Baagøe
name: Lyngstad, Merete
name: Rotegård, Ann Kristin
name: Slettebø, Åshild
name: Fossum, Mariann
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 2.
title: Kurt Huber und das Volkslied
Creators: name: Focht, Josef
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2012

description: Der Münchner Hochschullehrer Kurt Huber (1893–1943) genießt als Widerstandskämpfer gegen das NS-Regime und Mitglied der Weissen Rose hohes Ansehen. Ungeachtet dessen stand sein wissenschaftliches und publizistisches Bemühen um das sog. Volkslied in den Jahren 1925 bis 1943 ganz im Dienst der NS-Kulturpolitik.
Additional file 1 of Time-dependent memory and individual variation in Arctic brown bears (Ursus arctos)
Creators: name: Thompson, Peter R.
name: Lewis, Mark A.
name: Edwards, Mark A.
name: Derocher, Andrew E.
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1. Appendix providing additional modelling details along with tables that further characterize our results.
Inflammatory arthritis and systemic bone loss are attenuated by gastrointestinal helminth parasites
Creators: name: Sarter, Kerstin
name: Kulagin, Manuel
name: Schett, Georg
name: Harris, Nicola L.
name: Zaiss, Mario M.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Infections with different helminth species have been observed to ameliorate a variety of chronic inflammatory diseases. Herein, we show that the natural murine helminth species, Heligmosomoides polygyrus bakeri (Hp) is capable of attenuating disease severity in two different inflammatory arthritis models. Furthermore, we show that excretory–secretory (ES) products from Hp directly suppress osteoclast differentiation in vitro. Taken together, these results demonstrate that helminth infections can dampen autoimmune diseases and highlight a previously unrecognized and important role for ES products, by directly impacting on bone destruction.
Characterization of chicken interferon-inducible transmembrane protein-10
Creators: name: Okuzaki, Yuya
name: Kidani, Shunsuke
name: Kaneoka, Hidenori
name: Iijima, Shinji
name: Ken-Ichi Nishijima
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Interferon-inducible transmembrane protein (IFITM) family proteins are antivirus factors. In the present study, we examined the expression pattern of chicken IFITM10 using quantitative reverse transcription-polymerase chain reaction. In adult chickens, IFITM10 levels were markedly lower than those of IFITM3, which exhibits antivirus activity. On the other hand, IFITM10 was expressed in levels similar to those of IFITM3 in embryonic organs. Primordial germ cells in 2.5-d embryos expressed high levels of IFITM10, which gradually decreased with time. The interferon-α stimulation of embryonic fibroblast cells did not enhance the expression of IFITM10. The forced expression of IFITM10 slightly inhibited the infectivity of the VSV-G-pseudotyped lentiviral vector. Furthermore, cell fusion was inhibited by IFITM10 when HeLa cells transfected with the VSV-G expression vector were treated with low pH buffer. Although it remains unclear whether IFITM10 inhibits viral infections under physiological conditions, these results suggest that chicken IFITM10 exhibits antivirus activity. Explanation for the graphical abstract (Okuzaki et al.) Chicken IFITM10 inhibits VSV-G-pseudotyped lentiviral vector infection and VSV-G-mediated cell fusion.
Additional file 1 of Genomic variation in baboons from central Mozambique unveils complex evolutionary relationships with other Papio species
Creators: name: Santander, Cindy
name: Molinaro, Ludovica
name: Mutti, Giacomo
name: Martínez, Felipe I.
name: Mathe, Jacinto
name: Ferreira da Silva, Maria Joana
name: Caldon, Matteo
name: Oteo-Garcia, Gonzalo
name: Aldeias, Vera
name: Archer, Will
name: Bamford, Marion
name: Biro, Dora
name: Bobe, René
name: Braun, David R.
name: Hammond, Philippa
name: Lüdecke, Tina
name: Pinto, Maria José
name: Meira Paulo, Luis
name: Stalmans, Marc
name: Regala, Frederico Tátá
name: Bertolini, Francesco
name: Moltke, Ida
name: Raveane, Alessandro
name: Pagani, Luca
name: Carvalho, Susana
name: Capelli, Cristian
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Distribution, location, and heterozygosity of samples (Figure S1). mtDNA phylogenetics (Figure S2). Y chromosome data & phylogenetics. qpGraph (Figure S3). TreeMix (Figure S4). PSMC (Figures S5–S6). Characterizing P. cynocephalus ancestry in P. anubis (Figures S7–S8).
MTNR1A and MTNR1B gene polymorphisms in women with gestational diabetes
Creators: name: Tarnowski, Maciej
name: Malinowski, Damian
name: Safranow, Krzysztof
name: Dziedziejko, Violetta
name: Pawlik, Andrzej
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Gestational diabetes mellitus (GDM) is glucose intolerance detected during pregnancy. The MTNR1B gene is the genetic locus associated with type 2 diabetes, that may affect insulin secretion and pancreatic glucose sensing. In this study, we examined the association between MTNR1A (rs2119882) and MTNR1B (rs10830963, rs4753426) gene polymorphisms and the risk of GDM. According to the results of their oral glucose tolerance test (OGTT), the women were divided into two groups: 204 pregnant women with GDM and 207 pregnant women with normal glucose tolerance (NGT). There were no statistically significant differences in the distribution of MTNR1A rs2119882 and MTNR1B rs4753426 genotypes and alleles between women with GDM and healthy pregnant women. With regard to the MTNR1B rs10830963 polymorphism, we observed a statistically significant prevalence of GG and CG genotypes and the G allele among pregnant women with GDM (GG + CG vs CC, OR 1.50, 95% CI 1.02–2.22, p = 0.04; G vs C, OR 1.43, 95% CI 1.07–1.90, p = 0.016). In a multivariate logistic regression analysis, a higher number of MTNR1B rs10830963 G alleles was an independent significant predictor of a higher risk of GDM. The results of our study indicate that MTNR1B rs10830963 polymorphism is associated with GDM susceptibility, and women with a higher number of G alleles have an increased risk of GDM development.
QANDLI DIABETNING KELIB CHIQISH SABABLARI VA UNI DAVOLASH
Creators: name: Suyarova, Sunbula
name: Asatova, Feruza
name: Uzoqova, Marjona
name: Kurbanova, Nozima
Publisher: name: Zenodo
Year: 2024

description: Diabetes mellitus-bu qon glyukoza darajasining ko‘tarilishi bilan tavsiflangan surunkali metabolik kasallik. Ushbu maqola diabetning asosiy sabablarini, uning tasniflarini va uni davolashdagi yutuqlarni o‘rganadi. Adabiyotlarni tahlil qilish orqali insulin terapiyasi, og‘iz orqali qabul qilinadigan dorilar va doimiy glyukoza monitoringi (CGM) va sun'iy oshqozon osti bezi tizimlari kabi rivojlanayotgan texnologiyalar kabi terapevtik yondashuvlar bilan bir qatorda diabetga olib keladigan genetik, ekologik va turmush tarzi omillari tekshiriladi. Muhokamada diabetni davolash va boshqarish strategiyasini takomillashtirish bo‘yicha tavsiyalar mavjud.
Supplementary Methods from Functional characterization of the TAS2R38 bitter taste receptor for phenylthiocarbamide in colobine monkeys
Creators: name: Laurentia Henrieta Permita Sari Purba
name: Kanthi Arum Widayati
name: Tsutsui, Kei
name: Suzuki-Hashido, Nami
name: Hayakawa, Takashi
name: Nila, Sarah
name: Bambang Suryobroto
name: Imai, Hiroo
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Behavioral experiments, Genotyping of TAS2R38, and Expression vector and site-directed mutagenesis
Supplementary figure S2 from Functional characterization of the TAS2R38 bitter taste receptor for phenylthiocarbamide in colobine monkeys
Creators: name: Laurentia Henrieta Permita Sari Purba
name: Kanthi Arum Widayati
name: Tsutsui, Kei
name: Suzuki-Hashido, Nami
name: Hayakawa, Takashi
name: Nila, Sarah
name: Bambang Suryobroto
name: Imai, Hiroo
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Responses of colobines (N. larvatus B) with mutant TAS2R38 mimicking the macaque-type receptor.
Additional file 1 of Intensive care unit to unit capacity transfers are associated with increased mortality: an observational cohort study on patient transfers in the Swedish Intensive Care Register
Creators: name: Parenmark, Fredric
name: Walther, Sten M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1. Additional Tables.
Further Methods from Long-term memory of relative reward values
Creators: name: Soldati, Francesca
name: Burman, Oliver H. P.
name: John, Elizabeth A.
name: Pike, Thomas W.
name: Wilkinson, Anna
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour

description: Details of experimental methods
Analysis results of rest quadrats. Co-occurrence patterns of ice-rafted dropstones and brachiopods in the Middle Permian Wandrawandian Siltstone of the southern Sydney Basin (southeastern Australia) and palaeoecological implications
Creators: name: Yang, Bo
name: Shi, G. R.
name: Lee, Sangmin
name: Luo, Mao
Publisher: name: Geological Society of London
Year: 2018

description: Supplementary Material 2: Analysis results of rest quadrats
The spatiotemporal interpretation of wave function may solve the mystery of quantum entanglement
Creators: name: Deng, Xiao-han
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 510802
subject: Foundations of quantum mechanics

description: In this paper, the wave function is interpreted as space-time: under any representation, the real part of the wave function represents space and the imaginary part represents time. A wave function represents the quantum entanglement (correlation) between time and space. The unitary evolution process is the mutual transformation of space-time. The imaginary time indicates that it can entangle with space in a non localized way and dominate the integrity (unification) of a quantum, which is the essence of quantum entanglement.
Additional file 1: of Whole genome sequencing data of 1110 Mycobacterium tuberculosis isolates identifies insertions and deletions associated with drug resistance
Creators: name: Zeng, Xi
name: Kwok, Jamie
name: Yang, Kevin
name: Leung, Kenneth
name: Shi, Mai
name: Yang, Zhiyuan
name: Yam, Wing-Cheong
name: Tsui, Stephen
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Figure S1. The profile of 1110 isolates. (a) The distribution of isolates in three studies. (b) The drug profiles for the 1110 isolates. Figure S2. Boxplot of the FS mutation numbers in the drug-resistant and -sensitive strains for each drug. The p-values refer to corrected p-values. Figure S3. Boxplot of the IGR indel numbers in the drug-resistant and -sensitive strains for each drug. The p-values refer to corrected p-values. Figure S4. Boxplot of the FS mutation numbers in the DR-TB, MDR-TB and XDR-TB groups of strains. The distribution of the number of FS mutations is shown. A Wilcoxon rank sum test was used to test the differences among the DR-TB, MDR-TB and XDR-TB groups. Figure S5. Protein-protein interaction for genes with frameshift indels in DR-TB strains. Figure S6. Protein-protein interaction for genes with frameshift indels in pan-susceptible strains comparing to DR-TB group. First, the FS mutations also existing in DR-TB strains were excluded. Then, the remained FS mutation in pan-susceptible strains were annotated onto the genes. The obtained gene list combined with known resistance-associated genes was inputted into STRING. The thicker the lines between two proteins, the stronger the relationship between them. The protein-protein interaction analysis took into consideration the following factors: the presence of fusion evidence, neighborhood evidence, co-occurrence evidence, experimental evidence, text mining evidence, database evidence and co-expression evidence. Figure S7. Validations using another data set. (a) Comparison of the FS indel numbers between drug-resistant and -sensitive strains. (b). Comparison of the IGR indel numbers between drug resistant and sensitive strains. (c). The Correlation between DNA repair mutation numbers and FS + IGR indel numbers. Each dot represents an MTB strain. (DOCX 10447Â kb)
Additional file 1 of Transcriptional and proteomic insights into phytotoxic activity of interspecific potato hybrids with low glycoalkaloid contents
Creators: name: Szajko, Katarzyna
name: Ciekot, Jarosław
name: Wasilewicz-Flis, Iwona
name: Marczewski, Waldemar
name: Sołtys-Kalina, Dorota
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1: Supplementary Table S1. Average retention time (RT) and mass of compounds found in samples D and C.
MOESM1 of Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study
Creators: name: Guo, Yi
name: Musani, Solomon
name: Sims, Mario
name: Pearson, Thomas
name: DeBoer, Mark
name: Gurka, Matthew
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Virology
Computational Biology

description: Additional file 1: Table S1. Cox Proportional Hazards Models: Time to Incident CVD, Overall and by Sex and Race: Risk Scores and HOMA-IR. Table S2. Logistic Models for Predicting Type 2 Diabetes, Overall and by Sex and Race: Risk Scores and HOMA-IR.
Additional file 2 of Transcriptional and proteomic insights into phytotoxic activity of interspecific potato hybrids with low glycoalkaloid contents
Creators: name: Szajko, Katarzyna
name: Ciekot, Jarosław
name: Wasilewicz-Flis, Iwona
name: Marczewski, Waldemar
name: Sołtys-Kalina, Dorota
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 2: Supplementary Figure S1. Mass spectra of GAs found in samples C and D.
Additional file 2: of Whole genome sequencing data of 1110 Mycobacterium tuberculosis isolates identifies insertions and deletions associated with drug resistance
Creators: name: Zeng, Xi
name: Kwok, Jamie
name: Yang, Kevin
name: Leung, Kenneth
name: Shi, Mai
name: Yang, Zhiyuan
name: Yam, Wing-Cheong
name: Tsui, Stephen
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Table S1. Test for the difference in IGR indel incidence rate between resistant and sensitive strains for each drug among 1110 MTB strains. Table S2. Function enrichment for genes with at-least-one-drug-resistant strain-specific FS mutations in more than two resistant strains. Table S3. Function enrichment for genes with frameshift mutations in the DR-TB, MDR-TB and XDR-TB groups of strains. Table S4. The 20 region markers identified according to adjusted chi-square and Fisherâ s exact p-values. Table S5. The 20 identified region markers and corresponding strain numbers. Table S6. Overview of functions for 20 region markers. Table S7. Description of the 20 region markers. Table S8. The distribution of region markers in function categories. Table S9. The 83 identified point markers of FS mutations and IGR indels, showing adjusted p-values. Table S10. The 83 identified point markers of FS mutations and IGR indels, showing strain numbers. Table S11. The identified point markers located in the IGRs expressing sRNA. Table S12. Overview of the functions of the 83 point markers. Table S13. Descriptions of the functions of the 83 point markers. Table S14. The 6 point markers out of the 83 point markers exclusively occurring in resistant strains. Table S15. P-values after logistic regression for the associations between the 20 region markers and drug resistance. Table S16. P-values after logistic regressions for the associations between the 83 point markers and drug resistance. Table S17. Effect of mutations on DNA repair genes. Table S18. Region markers in the validation set overlapping with the 20 region markers. Table S19. Point markers in the validation set overlapping with the 83 point markers. Table S20. Point markers in the 62 samples in which no known drug resistance associated SNPs were found. Table S21. The incidence rate for region markers. Table S22. The incidence rate for point markers. (DOCX 193Â kb)
Additional file 1: of Local infiltration anesthesia versus epidural analgesia for postoperative pain control in total knee arthroplasty: a systematic review and meta-analysis
Creators: name: Li, Chen
name: Qu, Ji
name: Pan, Su
name: Qu, Yang
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Figure S1. Subgroup analysis of the VAS with mobilization at 24, 48, and 72 h (single-shot local infiltration anesthesia or continuous local infiltration anesthesia, A VAS with rest at 24 h, B VAS with rest at 48 h, and C VAS with rest at 72 h). (DOCX 1384 kb)
Additional file 5 of Transcriptional and proteomic insights into phytotoxic activity of interspecific potato hybrids with low glycoalkaloid contents
Creators: name: Szajko, Katarzyna
name: Ciekot, Jarosław
name: Wasilewicz-Flis, Iwona
name: Marczewski, Waldemar
name: Sołtys-Kalina, Dorota
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 5: Supplementary Table S4. Expression pattern of UDP-glucosytransferases and other genes engaged in GAs biosynthesis between the bulks D vs. C, sorted by Log2 FC.
Supplementary figure S1 from Functional characterization of the TAS2R38 bitter taste receptor for phenylthiocarbamide in colobine monkeys
Creators: name: Laurentia Henrieta Permita Sari Purba
name: Kanthi Arum Widayati
name: Tsutsui, Kei
name: Suzuki-Hashido, Nami
name: Hayakawa, Takashi
name: Nila, Sarah
name: Bambang Suryobroto
name: Imai, Hiroo
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Amino acid sequence variation in TAS2R38 of leaf-eating monkeys
Additional file 1: of Echinococcus multilocularis and Echinococcus shiquicus in a small mammal community on the eastern Tibetan Plateau: host species composition, molecular prevalence, and epidemiological implications
Creators: name: Wang, Xu
name: Liu, Jiayu
name: Zuo, Qingqiu
name: Mu, Zhiqiang
name: Weng, Xiaodong
name: Sun, Xiaohui
name: Wang, Junyao
name: Boufana, Belgees
name: Craig, Philip
name: Giraudoux, Patrick
name: Raoul, Francis
name: Wang, Zhenghuan
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Table S1. Information for cox1 sequences used in the Bayesian phylogenic tree in this study. Table S2. Echinococcus detection results of each suspected small mammal sample based on necropsy and molecular analyses. (DOCX 35 kb)
Additional file 1 of Locally adapting generic rubrics for the implementation of outcome-based medical education: a mixed-methods approach
Creators: name: Kondo, Takeshi
name: Nishigori, Hiroshi
name: van der Vleuten, Cees
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1.
Additional file 2 of Locally adapting generic rubrics for the implementation of outcome-based medical education: a mixed-methods approach
Creators: name: Kondo, Takeshi
name: Nishigori, Hiroshi
name: van der Vleuten, Cees
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 2.
Additional file 2: of Local infiltration anesthesia versus epidural analgesia for postoperative pain control in total knee arthroplasty: a systematic review and meta-analysis
Creators: name: Li, Chen
name: Qu, Ji
name: Pan, Su
name: Qu, Yang
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Virology

description: Figure S2. Subgroup analysis of the VAS with rest at 12, 24, 48, and 72 h (single-shot local infiltration anesthesia or continuous local infiltration anesthesia, A VAS with rest at 12 h, B VAS with rest at 24 h, C VAS with rest at 48 h, D VAS with rest at 72 h). (DOCX 2027 kb)
The risk of gastrointestinal bleeding in patients receiving dabigatran etexilate: a systematic review and meta-analysis of the literature
Creators: name: Minno, Matteo Nicola Dario Di
name: Ambrosino, Pasquale
name: Minno, Alessandro Di
name: Tremoli, Elena
name: Minno, Giovanni Di
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology
subject: Cardiology

description: Background: Evidence on the risk of gastrointestinal (GI) bleeding associated with dabigatran etexilate (DE) is contrasting. We performed a meta-analysis of literature to address this issue. Methods and Results: Studies on GI bleeding risk in patients receiving DE or vitamin-K antagonists (VKA) were systematically searched. Twenty-three studies (26 datasets) showed no difference in the GI bleeding risk between the 250,871 patients treated with DE and the 460,386 receiving VKA (OR: 1.052, 95% CI: 0.815, 1.359). Similar results were obtained when pooling together adjusted ORs/HRs, obtained by means of multivariate analysis (OR: 1.06, 95% CI: 0.914, 1.222). Compared with VKA, DE use was associated with a significantly lower risk of upper GI (OR: 0.742, 95% CI: 0.569, 0.968), but not of lower GI bleedings (OR: 1.208, 95% CI: 0.902, 1.619). Furthermore, no significant difference in the GI bleeding risk was found when data on DE 110 mg and DE 150 mg twice-daily were separately compared with VKA. Conclusions: No difference in GI bleeding risk was found between DE and VKA. These results were confirmed for both dosages of DE and when specifically analyzing lower GI bleeding. In contrast, the risk of upper GI bleeding was lower with DE than with VKA.KEY MESSAGESNo difference in the risk of gastrointestinal (GI) bleeding can be found between dabigatran etexilate (DE) and vitamin K-antagonists (VKA).These results are confirmed for both dosages of DE.The risk of upper GI bleeding is lower with DE than with VKA. No difference in the risk of gastrointestinal (GI) bleeding can be found between dabigatran etexilate (DE) and vitamin K-antagonists (VKA). These results are confirmed for both dosages of DE. The risk of upper GI bleeding is lower with DE than with VKA.
Additional file 3 of Locally adapting generic rubrics for the implementation of outcome-based medical education: a mixed-methods approach
Creators: name: Kondo, Takeshi
name: Nishigori, Hiroshi
name: van der Vleuten, Cees
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 3.
Bioactive sesquiterpenes from an endophytic fungus Bipolaris sorokiniana isolated from a popular medicinal plant Costus speciosus
Creators: name: M. Mallique Qader
name: N. Savitri Kumar
name: Jayasinghe, Lalith
name: Araya, Hiroshi
name: Fujimoto, Yoshinori
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Bipolaris sorokiniana, a fungal endophyte, was isolated from the leaves of Costus speciosus, a popular medicinal plant used to control diabetes. Fermentation of the fungus in potato dextrose broth and chromatographic purification of the ethyl acetate (EtOAc) extracts of the culture broth and mycelium yielded two rare sesquiterpenes helminthosporal acid (1) and helminthosporol (2), together with ergosterol. Compounds 1 and 2 showed a strong phytotoxic effect on lettuce seed germination and toxicity against brine shrimps. Compound 1 also showed antifungal activity. Complete assignments of 1H and 13C NMR data of compound 1 are described for the first time.
Additional file 1 of Determinants of food insecurity among households with children in Villa el Salvador, Lima, Peru: the role of gender and employment, a cross-sectional study
Creators: name: Santos, M. Patrizia
name: Brewer, Jessica D.
name: Lopez, Miguel A.
name: Paz-Soldan, Valerie A.
name: Chaparro, M. Pia
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1.
Space Weather Impacts on Ireland
Creators: name: Gallagher, Peter
name: Murray, Sophie
Publisher: name: figshare
Year: 2017
Subjects: subject: 20109 Space and Solar Physics
subject: FOS: Physical sciences

description: Presentation on possible effects of space weather on Irish technological systems during a solar super storm.
Given at the Office of Emergency Planning, Department of Defence on Kildare Street, Dublin (Jan 2017) as part of review of risks to Irish society, security and economy.
Additional file 1 of The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates
Creators: name: Stovner, Lars Jacob
name: Hagen, Knut
name: Linde, Mattias
name: Steiner, Timothy J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 1. Studies included in the analysis.
Additional file 1 of Predictive ability of the health belief model in HIV testing and counselling uptake among youth aged 15–24 in La-Nkwantanang-Madina Municipality, Ghana
Creators: name: Appau, Rosemond
name: Aboagye, Richard Gyan
name: Nyahe, Morkporkpor
name: Khuzwayo, Nelisiwe
name: Tarkang, Elvis Enowbeyang
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
Additional file 2 of The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates
Creators: name: Stovner, Lars Jacob
name: Hagen, Knut
name: Linde, Mattias
name: Steiner, Timothy J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: Additional file 2.
Oxidation and degradation of polypropylene transvaginal mesh
Creators: name: Talley, Anne D.
name: Rogers, Bridget R.
name: Iakovlev, Vladimir
name: Dunn, Russell F.
name: Guelcher, Scott A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Polypropylene (PP) transvaginal mesh (TVM) repair for stress urinary incontinence (SUI) has shown promising short-term objective cure rates. However, life-altering complications have been associated with the placement of PP mesh for SUI repair. PP degradation as a result of the foreign body reaction (FBR) has been proposed as a contributing factor to mesh complications. We hypothesized that PP oxidizes under in vitro conditions simulating the FBR, resulting in degradation of the PP. Three PP mid-urethral slings from two commercial manufacturers were evaluated. Test specimens (n = 6) were incubated in oxidative medium for up to 5 weeks. Oxidation was assessed by Fourier Transform Infrared Spectroscopy (FTIR), and degradation was evaluated by scanning electron microscopy (SEM). FTIR spectra of the slings revealed evidence of carbonyl and hydroxyl peaks after 5 weeks of incubation time, providing evidence of oxidation of PP. SEM images at 5 weeks showed evidence of surface degradation, including pitting and flaking. Thus, oxidation and degradation of PP pelvic mesh were evidenced by chemical and physical changes under simulated in vivo conditions. To assess changes in PP surface chemistry in vivo, fibers were recovered from PP mesh explanted from a single patient without formalin fixation, untreated (n = 5) or scraped (n = 5) to remove tissue, and analyzed by X-ray photoelectron spectroscopy. Mechanical scraping removed adherent tissue, revealing an underlying layer of oxidized PP. These findings underscore the need for further research into the relative contribution of oxidative degradation to complications associated with PP-based TVM devices in larger cohorts of patients.
Additional file 1 of Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin
Creators: name: Chen, Hsin-Hsiung
name: Lu, Hao-Yu
name: Chang, Chao-Hsin
name: Lin, Shih-Hao
name: Huang, Chu-Wei
name: Wei, Po-Han
name: Chen, Yi-Wen
name: Lin, Yi-Rou
name: Huang, Hsien-Sung
name: Wang, Pei-Yu
name: Tsao, Yeou-Ping
name: Chen, Show-Li
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Cell Biology
Molecular Biology
Neuroscience
Developmental Biology
Science Policy

description: Additional file 1. Supplemental Figures.
Additional file 1: of Comparison of outcomesÂ in emergency department patients with suspected cardiac chest pain: two-centre prospective observationalÂ study in Southern China
Creators: name: Jiang, Huilin
name: Li, Yunmei
name: Mo, Junrong
name: Chen, Xiaohui
name: Li, Min
name: Lin, Peiyi
name: Hung, Kevin
name: Rainer, Timothy
name: Graham, Colin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Mental Health

description: Definition of HEART score [29]: There were five elements: history, ECG, age,risk factors and troponin in HEART score. Each variable was scored asÂ 0, 1 or 2 points. Each patient will receive a score of 1-10. (DOCX 32 kb)
Additional file 2 of Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin
Creators: name: Chen, Hsin-Hsiung
name: Lu, Hao-Yu
name: Chang, Chao-Hsin
name: Lin, Shih-Hao
name: Huang, Chu-Wei
name: Wei, Po-Han
name: Chen, Yi-Wen
name: Lin, Yi-Rou
name: Huang, Hsien-Sung
name: Wang, Pei-Yu
name: Tsao, Yeou-Ping
name: Chen, Show-Li
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Cell Biology
Molecular Biology
Neuroscience
Developmental Biology
Science Policy

description: Additional file 2. Supplemental Table.