cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists
Creators: name: Zhu, H.
name: Kenakin, T.
name: McCorvy, J.D.
name: Kozikowski, A.P.
name: Giguere, P.M.
name: Roth, B.L.
name: Cheng, J.
Publisher: name: American Chemical Society
Year: 2016

description: On the basis of the structural similarity of our previous 5-HT2C agonists with the melatonin receptor agonist tasimelteon and the putative biological cross-talk between serotonergic and melatonergic systems, a series of new (2,3-dihydro)benzofuran-based compounds were designed and synthesized. The compounds were evaluated for their selectivity toward 5-HT2A, 5-HT2B, and 5-HT2C receptors in the calcium flux assay with the ultimate goal to generate selective 5-HT2C agonists. Selected compounds were studied for their functional selectivity by comparing their transduction efficiency at the G protein signaling pathway versus β-arrestin recruitment. The most functionally selective compound (+)-7e produced weak β-arrestin recruitment and also demonstrated less receptor desensitization compared to serotonin in both calcium flux and phosphoinositide (PI) hydrolysis assays. We report for the first time that selective 5-HT2C agonists possessing weak β-arrestin recruitment can produce distinct receptor desensitization properties. © 2016 American Chemical Society.
Asymptotics of Chebyshev Polynomials, I. Subsets of $\mathbb{R}$
Creators: name: Christiansen, Jacob S.
name: Simon, Barry
name: Zinchenko, Maxim
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 41A50, 30E15, 30C10

description: We consider Chebyshev polynomials, $T_n(z)$, for infinite, compact sets $\frak{e} \subset \mathbb{R}$ (that is, the monic polynomials minimizing the sup-norm, $\Vert T_n \Vert_{\frak{e}}$, on $\frak{e}$). We resolve a $45+$ year old conjecture of Widom that for finite gap subsets of $\mathbb{R}$, his conjectured asymptotics (which we call Szegő-Widom asymptotics) holds. We also prove the first upper bounds of the form $\Vert T_n \Vert_{\frak{e}} \leq Q C({\frak{e}})^n$ (where $C(\frak{e})$ is the logarithmic capacity of $\frak{e}$) for a class of $\frak{e}$'s with an infinite number of components, explicitly for those $\frak{e} \subset \mathbb{R}$ that obey a Parreau-Widom condition.
description: 29 pages
Publizistischer Aufbruch in der schweizerischen Geschlechterforschung
Creators: name: Fankhauser, Lilian
Publisher: name: Humboldt-Universität zu Berlin
Year: 2003
Subjects: subject: Geschlechterforschung
subject: Wissenschaft
subject: Feminismus
subject: 050 Zeitschriften, allgemeine fortlaufende Sammelwerke
subject: Publizieren

description: Die Reihe gender wissen und die Zeitschrift Nouvelles Questions Féministes, zwei neue interdisziplinäre Publikationsorgane für Geschlechterforschung und feministische Wissenschaft in der Schweiz, die es zu entdecken gilt.
Local order metrics for many-particle systems across length scales
Creators: name: Maher, Charles Emmett
name: Torquato, Salvatore
Publisher: name: arXiv
Year: 2024
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Formulating order metrics that sensitively quantify the degree of order/disorder in many-particle systems in $d$-dimensional Euclidean space $\mathbb{R}^d$ across length scales is an outstanding challenge in physics, chemistry, and materials science. Since an infinite set of $n$-particle correlation functions is required to fully characterize a system, one must settle for a reduced set of structural information, in practice. We initiate a program to use the local number variance $σ_N^2(R)$ associated with a spherical sampling window of radius $R$ (which encodes pair correlations) and an integral measure derived from it $Σ_N(R_i,R_j)$ that depends on two specified radial distances $R_i$ and $R_j$. Across the first three space dimensions ($d = 1,2,3$), we find these metrics can sensitively describe and categorize the degree of order/disorder of 41 different models of antihyperuniform, nonhyperuniform, disordered hyperuniform, and ordered hyperuniform many-particle systems at a specified length scale $R$. Using our local variance metrics, we demonstrate the importance of assessing order/disorder with respect to a specific value of $R$. These local order metrics could also aid in the inverse design of structures with prescribed length-scale-specific degrees of order/disorder that yield desired physical properties. In future work, it would be fruitful to explore the use of higher-order moments of the number of points within a spherical window of radius $R$ [S. Torquato {\it et al}., Phys. Rev. X, \textbf{11}, 021028 (2021)] to devise even more sensitive order metrics.
description: 19 pages, 8 figures
title: Approach to Endovascular Management of High Flow Priapism
Creators: name: Abdel Aal, Ahmed
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Trauma
subject: Fistula
subject: Embolisation
subject: Catheter arteriography
subject: Vascular

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Recognize the types and Clinical presentation of Priapism. Understand the imaging findings of high flow priapism (HFP). Outline variant management strategies. Discuss technique of embolization for HFP. Outline the potential complications and...
title: Predicting Subtypes of Thymic Epithelial Tumors Using CT based on random forest
Creators: name: Shen, Qijun
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Image verification
subject: Computer Applications-Detection, diagnosis
subject: CT
subject: Mediastinum

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Accurately estimating the risks of thymic epithelial tumors (TETs) is of great guiding significance to choice of treatment approaches. However, TET’s WHO histological classification is very complex[1], and its correlation with CT findings is still...
Crystallization of space: Space-time fractals from fractal arithmetic
Creators: name: Aerts, Diederik
name: Czachor, Marek
name: Kuna, Maciej
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Fractals such as the Cantor set can be equipped with intrinsic arithmetic operations (addition, subtraction, multiplication, division) that map the fractal into itself. The arithmetics allows one to define calculus and algebra intrinsic to the fractal in question, and one can formulate classical and quantum physics within the fractal set. In particular, fractals in space-time can be generated by means of homogeneous spaces associated with appropriate Lie groups. The construction is illustrated by explicit examples.
description: version accepted in Chaos, Solitons & Fractals
(103380) John William Heaven
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models
Creators: name: Giguere, P.M.
name: Huang, X.-P.
name: Cheng, J.
name: Kozikowski, A.P.
name: Roth, B.L.
name: Schmerberg, C.M.
name: Wetsel, W.C.
name: McCorvy, J.D.
name: Pogorelov, V.M.
name: Zhu, H.
name: Rodriguiz, R.M.
Publisher: name: American Chemical Society
Year: 2016

description: A series of novel compounds with two halogen substituents have been designed and synthesized to further optimize the 2-phenylcyclopropylmethylamine scaffold in the quest for drug-like 5-HT2C agonists. Compound (+)-22a was identified as a potent 5-HT2C receptor agonist, with good selectivity against the 5-HT2B and the 5-HT2A receptors. ADMET assays showed that compound (+)-22a possessed desirable properties in terms of its microsomal stability, and CYP and hERG inhibition, along with an excellent brain penetration profile. Evaluation of (+)-22a in animal models of schizophrenia-related behaviors revealed that it had a desirable activity profile, as it reduced d-amphetamine-stimulated hyperlocomotion in the open field test, it restored d-amphetamine-disrupted prepulse inhibition, it induced cognitive improvements in the novel object recognition memory test in NR1-KD animals, and it produced very little catalepsy relative to haloperidol. These data support the further development of (+)-22a as a drug candidate for the treatment of schizophrenia.
Comment on Article by Dawid and Musio
Creators: name: Katzfuss, Matthias
name: Bhattacharya, Anirban
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: Discussion of "Bayesian Model Selection Based on Proper Scoring Rules" by Dawid and Musio [arXiv:1409.5291].
description: Published at http://dx.doi.org/10.1214/15-BA942A in the Bayesian Analysis (http://projecteuclid.org/euclid.ba) by the International Society of Bayesian Analysis (http://bayesian.org/)
title: Frustrated from the gastric fundal loop in gastrojejunostomy catheter placement and exchange. How can I reduce it?
Creators: name: Abdel Aal, Ahmed
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Fluoroscopy
subject: Stomach (incl. Oesophagus)
subject: Gastrointestinal tract
subject: Technical aspects
subject: Outcomes

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Outline indications and alternatives for trans-pyloric feeding. Recognize the causes of gastrojejunostomy malfunction. Illustratethe technique for fundalloop reduction. Discuss the advantages of our...
Towards a first estimate of the gluon Sivers function from $A_N$ data in $pp$ collisions at RHIC
Creators: name: D'Alesio, U.
name: Murgia, F.
name: Pisano, C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Within a generalized parton model approach, with inclusion of spin and intrinsic transverse momentum effects, we show how the latest, highly precise, midrapidity data on the transverse single spin asymmetry measured in $pp\toπ^0\, X$ by the PHENIX Collaboration at RHIC [1], can be used to get a first estimate on the still poorly known gluon Sivers distribution. To this end we also adopt the present information on the quark Sivers functions, as extracted from semi-inclusive deeply inelastic scattering data. This analysis updates a previous study by some of us where a first bound on this distribution was obtained [2].
description: RevTex4, 10 pages, 7 eps figures. V2: discussion on the process dependence of the quark Sivers function, with two new plots (Fig. 4), added in Section II. One reference added. Results unchanged. Matches the published version
New Technologies for Elucidating Opioid Receptor Function
Creators: name: Bruchas, M.R.
name:  Roth, B.L.
Publisher: name: Elsevier Ltd
Year: 2016

description: Recent advances in technology, including high resolution crystal structures of opioid receptors, novel chemical tools, and new genetic approaches have provided an unparalleled palette of tools for deconstructing opioid receptor actions in vitro and in vivo. Here we provide a brief description of our understanding of opioid receptor function from both molecular and atomic perspectives, as well as their role in neural circuits in vivo. We then show how insights into the molecular details of opioid actions can facilitate the creation of functionally selective (biased) and photoswitchable opioid ligands. Finally, we describe how newly engineered opioid receptor-based chemogenetic and optogenetic tools, and new mouse lines, are expanding and transforming our understanding of opioid function and, perhaps, paving the way for new therapeutics. © 2016 Elsevier Ltd. All rights reserved.
title: Noise in the Pediatric Chest X-ray – Do Radiologists and Radiographers Speak the Same Language?
Creators: name: Jensen, Janni
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Quality assurance
subject: Perception image
subject: Digital radiography
subject: Paediatric
subject: Lung

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Sub-optimal image quality of an x-ray may potentially influence the interpretation and consequently alter the diagnostic accuracy. For the pediatric patient in the acute setting, a chest x-ray may offer vital information and an image quality...
Massive Stars in the W33 Giant Molecular Complex
Creators: name: Messineo, Maria
name: Clark, J. Simon
name: Figer, Donald F.
name: Kudritzki, Rolf-Peter
name: Najarro, Francisco
name: Rich, R. Michael
name: Menten, Karl M.
name: Ivanov, Valentin D.
name: Valenti, Elena
name: Trombley, Christine
name: Chen, C. -H. Rosie
name: Davies, Ben
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Rich in HII regions, giant molecular clouds are natural laboratories to study massive stars and sequential star formation. The Galactic star forming complex W33 is located at l=~12.8deg and at a distance of 2.4 kpc, has a size of ~10 pc and a total mass of (~0.8 - ~8.0) X 10^5 Msun. The integrated radio and IR luminosity of W33 - when combined with the direct detection of methanol masers, the protostellar object W33A, and protocluster embedded within the radio source W33 main - mark the region out as a site of vigorous ongoing star formation. In order to assess the long term star formation history, we performed an infrared spectroscopic search for massive stars, detecting for the first time fourteen early-type stars, including one WN6 star and four O4-7 stars. The distribution of spectral types suggests that this population formed during the last ~2-4 Myr, while the absence of red supergiants precludes extensive star formation at ages 6-30 Myr. This activity appears distributed throughout the region and does not appear to have yielded the dense stellar clusters that characterize other star forming complexes such as Carina and G305. Instead, we anticipate that W33 will eventually evolve into a loose stellar aggregate, with Cyg OB2 serving as a useful, albeit richer and more massive, comparator. Given recent distance estimates, and despite a remarkably similar stellar population, the rich cluster Cl 1813-178 located on the north-west edge of W33 does not appear to be physically associated with W33.
description: ApJ (in press), 10 Figures
Development of CNS multi-receptor ligands: Modification of known D2pharmacophores
Creators: name: Etukala, J.R.
name: Ofori, E.
name: Onyameh, E.K.
name: Eyunni, S.V.K.
name: Kang, H.J.
name: Ablordeppey, S.Y.
name: Zhu, X.Y.
name: Roth, B.L.
name: Bricker, B.A.
name: Huang, X.-P.
Publisher: name: Elsevier Ltd
Year: 2016

description: Several known D2pharmacophores have been explored as templates for identifying ligands with multiple binding affinities at dopamine and serotonin receptors considered as clinically relevant receptors in the treatment of neuropsychiatric diseases. This approach has resulted in the identification of ligands that target multiple CNS receptors while avoiding others associated with deleterious effects. In particular, compounds 11, 15 and 22 may have potential for further development as antipsychotic agents as they favorably interact with the clinically relevant receptors including D2R, 5-HT1AR, and 5-HT7R. We have also identified the pair of compounds 11 and 10 as high affinity D2R ligands with and without SERT binding affinities, respectively. These differential binding profiles endow the pair with the potential for evaluating SERT contributions to antipsychotic drug activity in animal behavioral models. In addition, compound 11 has no significant affinity for 5-HT2CR and binds only moderately to the H1R, suggesting it may not induce weight gain or sedation when used clinically. Taken together, compound 11 displays an interesting pharmacological profile that necessitates the evaluation of its functional and in vivo effects in animal models which are currently ongoing.
(103381) Margaret Frances Heaven
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Does HMRS study show hemisphere differences in chemical composition in children?
Creators: name: Cichocka, Monika
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Metabolic disorders
subject: Experimental investigations
subject: MR-Spectroscopy
subject: Paediatric
subject: Neuroradiology brain

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The phenomenon of brain asymmetry is one of the most intriguing aspects of modern neurobiology. It has been observed in animals and humans at different levels: anatomical, functional and behavioral (1,2). It is already known that both hemispheres...
Grain size constraints on HL Tau with polarization signature
Creators: name: Kataoka, Akimasa
name: Muto, Takayuki
name: Momose, Munetake
name: Tsukagoshi, Takashi
name: Dullemond, Cornelis P
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The millimeter-wave polarization of the protoplanetary disk around HL Tau has been interpreted as the emission from elongated dust grains aligned with the magnetic field in the disk. However, the self-scattering of thermal dust emission may also explain the observed millimeter-wave polarization. In this paper, we report a modeling of the millimeter-wave polarization of the HL Tau disk with the self-polarization. Dust grains are assumed to be spherical and to have a power-law size distribution. We change the maximum grain size with a fixed dust composition in a fixed disk model to find the grain size to reproduce the observed signature. We find that the direction of the polarization vectors and the polarization degree can be explained with the self-scattering. Moreover, the polarization degree can be explained only if the maximum grain size is $\sim 150 {\rm~μm}$. The obtained grain size from the polarization is different from a size of millimeter or larger that has been previously expected from the spectral index of the dust opacity coefficient if the emission is optically thin. We discuss that porous dust aggregates may solve the inconsistency of the maximum grain size between the two constraints.
description: 9 pages, 8 figures, accepted for publication in ApJ
title: Community involvement as a model of mission for the local urban church
Creators: name: Williams, Andrew Martin
Publisher: name: University of Glasgow
Year: 2000
Subjects: subject: Church, mission, community development, church management.

description: This thesis attempts to answer the question 'Can community involvement be a model of mission for the local urban church?' The research is introduced with a discussion of the author's experience of church community involvement and the questions which arise from it. The changing social context of the Church in England and Scotland is outlined, before exploring recent developments in missiology and community involvement. The research methodology led to the exploration of mission through community involvement in two case studies of churches and their local communities. The case study research sought to be distinctive by listening primarily to people from the community speak about their perceptions of church community involvement. From analysis of this qualitative data, the key themes discovered in each case study are discussed and brought into dialogue with the author's questions and the literature on missiology and community involvement. The study concludes by pointing towards community involvement as a model of mission, whilst recognising that is an authentic and costly way of being the church in a local urban community. The author ends with some reflections on the implications of the research for personal practice in mission and ministry.
A search for pair production of new light bosons decaying into muons
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for the pair production of new light bosons, each decaying into a pair of muons, is performed with the CMS experiment at the LHC, using a dataset corresponding to an integrated luminosity of 20.7 inverse femtobarns collected in proton-proton collisions at center-of-mass energy of sqrt(s) = 8 TeV. No excess is observed in the data relative to standard model background expectation and a model independent upper limit on the product of the cross section, branching fraction, and acceptance is derived. The results are compared with two benchmark models, the first one in the context of the next-to-minimal supersymmetric standard model, and the second one in scenarios containing a hidden sector, including those predicting a nonnegligible light boson lifetime.
description: Replaced with published version. Added journal reference
title: Aggressive fibromatosis as an uncommon cause of paediatric head and neck masses: The role of imaging in diagnosis and management.
Creators: name: CHAN, Chung Yan Grace
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Paediatric
subject: Head and neck
subject: Musculoskeletal soft tissue
subject: CT
subject: MR
subject: Digital radiography
subject: Diagnostic procedure
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To increase awareness of aggressive fibromatosis as a differential diagnosis for paediatric head and neck masses. Discussion of its imaging features and the role of imaging in diagnosis, treatment planning and disease...
Comprehensive characterization of the Published Kinase Inhibitor Set
Creators: name: Tropsha, A.
name: Kunkel, M.
name: Huang, X.-P.
name: Polley, E.
name: Atkinson, F.L.
name: Fedele, V.
name: Romanov, S.
name: Salah, E.
name: Drewry, D.H.
name: Teicher, B.A.
name: Overington, J.P.
name: Al Haj Zen, A.
name: Knapp, S.
name: Willson, T.M.
name: Müller, S.
name: Roth, B.L.
name: Zuercher, W.J.
name: Muratov, E.
name: Szklarz, M.
name: Mikolajczyk, J.
name: Bamborough, P.
name: Price, D.J.
name: Fourches, D.
name: Morris, J.
name: Lackey, K.E.
name: Elkins, J.M.
name: Sepetov, N.
name: Abdul Azeez, K.R.
Publisher: name: Nature Publishing Group
Year: 2016

description: Despite the success of protein kinase inhibitors as approved therapeutics, drug discovery has focused on a small subset of kinase targets. Here we provide a thorough characterization of the Published Kinase Inhibitor Set (PKIS), a set of 367 small-molecule ATP-competitive kinase inhibitors that was recently made freely available with the aim of expanding research in this field and as an experiment in open-source target validation. We screen the set in activity assays with 224 recombinant kinases and 24 G protein-coupled receptors and in cellular assays of cancer cell proliferation and angiogenesis. We identify chemical starting points for designing new chemical probes of orphan kinases and illustrate the utility of these leads by developing a selective inhibitor for the previously untargeted kinases LOK and SLK. Our cellular screens reveal compounds that modulate cancer cell growth and angiogenesis in vitro. These reagents and associated data illustrate an efficient way forward to increasing understanding of the historically untargeted kinome.
title: Afraid of cervical fractures?: An easy review of traumatic cervical fractures.
Creators: name: Morán Marsili, Joaquín
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Trauma
subject: Education
subject: Computer Applications-Detection, diagnosis
subject: MR
subject: CT
subject: Conventional radiography
subject: Trauma
subject: Neuroradiology spine
subject: Emergency

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review thetraumatic craniocervical junction injuries and subaxial cervical spine lesions according to the Subaxial Injury Classification and Scoring system...
(103379) Francis Gyde Heaven
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The high redshift star-formation history from carbon-monoxide intensity maps
Creators: name: Breysse, Patrick C.
name: Kovetz, Ely D.
name: Kamionkowski, Marc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We demonstrate how cosmic star-formation history can be measured with one-point statistics of carbon-monoxide intensity maps. Using a P(D) analysis, the luminosity function of CO-emitting sources can be inferred from the measured one-point intensity PDF. The star-formation rate density (SFRD) can then be obtained, at several redshifts, from the CO luminosity density. We study the effects of instrumental noise, line foregrounds, and target redshift, and obtain constraints on the CO luminosity density of order 10%. We show that the SFRD uncertainty is dominated by that of the model connecting CO luminosity and star formation. For pessimistic estimates of this model uncertainty, we obtain an error of order 50% on SFRD for surveys targeting redshifts between 2 and 7 with reasonable noise and foregrounds included. However, comparisons between intensity maps and galaxies could substantially reduce this model uncertainty. In this case our constraints on SFRD at these redshifts improve to roughly 5-10%, which is highly competitive with current measurements.
description: 5 pages, 5 figures, Accepted to MNRASL
title: Comparison of PET-CT MR (3.0T) with 68Ga-PSMA for evaluation of prostate cancer patients with biochemical recurrence
Creators: name: Garcia Fontes, Margarita
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Genital / Reproductive system male
subject: Oncology
subject: MR
subject: PET
subject: PET-MR
subject: Molecular imaging
subject: Staging
subject: Neoplasia
subject: Multidisciplinary cancer care
subject: Outcomes

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Prostate cancer represents the most common cancer in men . Early detection of primary disease and its spread is relevant in terms of prognosis and therapy management. It is also very frequent, up to 50 % of all patients undergoing radical...
Relationship between Entropy and Diffusion: A statistical mechanical derivation of Rosenfeld expression for a rugged energy landscape
Creators: name: Seki, Kazuhiko
name: Bagchi, Biman
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Diffusion-a measure of dynamics, and entropy-a measure of disorder in the system, are found to be intimately correlated in many systems, and the correlation is often strongly non-linear. We explore the origin of this complex dependence by studying diffusion of a point Brownian particle on a model potential energy surface characterized by ruggedness. If we assume that the ruggedness has a Gaussian distribution then for this model, one can obtain the excess entropy exactly for any dimension. By using the expression for the mean first passage time (MFPT), we present a statistical mechanical derivation of the well-known and well-tested scaling relation proposed by Rosenfeld between diffusion and excess entropy. In anticipation that Rosenfeld diffusion-entropy scaling (RDES) relation may continue to be valid in higher dimensions (where the mean first passage time approach is not available), we carry out an effective medium approximation (EMA) based analysis of the effective transition rate, and hence of the effective diffusion coefficient. We show that the EMA expression can be used to derive the RDES scaling relation for any dimension higher than unity. However, RDES is shown to break down in the presence of spatial correlation among the energy landscape values.
description: 16 pages
title: Imaging features of myoepithelial carcinoma in the nasopharynx and paranasal sinus
Creators: name: Zhang, Chunyan
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Head and neck
subject: CT
subject: MR
subject: MR-Diffusion/Perfusion
subject: Surgery
subject: Biopsy

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Myoepithelial carcinoma (MEC) is also called malignant myoepithelioma (MME), it is a rare malignant tumor and often occur in salivary gland. The incidence of MEC was not more than 0.5% of all salivary gland tumors. MEC in the nasopharynx and...
Modification speed alters stability of ecological higher-order interaction networks
Creators: name: Van Giel, Thomas
name: Daly, Aisling J.
name: Baetens, Jan M.
name: De Baets, Bernard
Publisher: name: arXiv
Year: 2024
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 92D25

description: Higher-order interactions (HOIs) have the potential to greatly increase our understanding of ecological interaction networks beyond what is possible with established models that usually consider only pairwise interactions between organisms. While equilibrium values of such HOI-based models have been studied, the dynamics of these models and the stability of their equilibria remain underexplored. Here we present a novel investigation on the effect of the onset speed of a higher-order interaction. In particular, we study the stability of the equilibrium of all configurations of a three-species interaction network, including transitive as well as intransitive ones. We show that the HOI onset speed has a dramatic effect on the evolution and stability of the ecological network, with significant structural changes compared to commonly used HOI extensions or pairwise networks. Changes in the HOI onset speed from fast to slow can reverse the stability of the interaction network. The evolution of the system also affects the equilibrium that will be reached, influenced by the HOI onset speed. This implies that the HOI onset speed is an important determinant in the dynamics of ecological systems, and including it in models of ecological networks can improve our understanding thereof.
description: Main: 9 pages, supplementary: 9 pages
Comment on Article by Dawid and Musio
Creators: name: Hans, Christopher M.
name: Peruggia, Mario
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: Discussion of "Bayesian Model Selection Based on Proper Scoring Rules" by Dawid and Musio [arXiv:1409.5291].
description: Published at http://dx.doi.org/10.1214/15-BA942B in the Bayesian Analysis (http://projecteuclid.org/euclid.ba) by the International Society of Bayesian Analysis (http://bayesian.org/)
(103373) Frederick Monkman Driver
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Spin Casimir Effect in Non-collinear Quantum Antiferromagnets
Creators: name: Du, Z. Z.
name: Liu, H. M.
name: Xie, Y. L.
name: Wang, Q. H.
name: Liu, J. -M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Casimir effect is a general phenomenon in physics, which arises when the vacuum fluctuation of an arbitrary field is modified by static or slowly varying boundary. However, its spin version is rarely addressed, mainly due to the fact that a macroscopic boundary in quantum spin systems is hard to define. In this article, we explore the spin Casimir effect induced by the zero-point fluctuation of spin waves in a general non-collinear ordered quantum antiferromagnet. This spin Casimir effect results in a spin torque between local spins and further causes various singular and divergent results in the framework of spin-wave theory, which invalidate the standard $1/S$ expansion procedure. To avoid this dilemma, we develop a self-consistent spin-wave expansion approach, which preserves the spin-wave expansion away from singularities and divergence. A detailed spin-wave analysis of the antiferromagnetic spin-1/2 Heisenberg model on a spatially anisotropic triangular lattice is undertaken within our approach. Our results indicate that the spiral order is only stable in the region $0.5
description: 14 pages, 8 figures. Comments and advice warmly welcome!
(103374) John Wallace Driver
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Vector and tensor contributions to the curvature perturbation at second order
Creators: name: Carrilho, Pedro
name: Malik, Karim A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We derive the evolution equation for the second order curvature perturbation using standard techniques of cosmological perturbation theory. We do this for different definitions of the gauge invariant curvature perturbation, arising from different splits of the spatial metric, and compare the expressions. The results are valid at all scales and include all contributions from scalar, vector and tensor perturbations, as well as anisotropic stress, with all our results written purely in terms of gauge invariant quantities. Taking the large-scale approximation, we find that a conserved quantity exists only if, in addition to the non-adiabatic pressure, the transverse traceless part of the anisotropic stress tensor is also negligible. We also find that the version of the gauge invariant curvature perturbation which is exactly conserved is the one defined with the determinant of the spatial part of the inverse metric.
description: 21 pages. Appendix added and conclusions extended. Updated to match version published in JCAP
title: MR perfusion perilesional oedema difference between glioblastoma and metastasis
Creators: name: Pérez Girbés, Alexandre
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neuroradiology brain
subject: MR-Diffusion/Perfusion
subject: Imaging sequences
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Brain metastases are the most frequent brain tumors in adults, and up to 20-40% of cancer patients will develop them throughout their illness (1). Approximately,50% of patients with metastatic brain disease present with single brain metastasis...
Evolution of entropic dark energy and its phantom nature
Creators: name: Mathew, Titus K.
name: Murali, Chinthak
name: J, Shejeelammal
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Assuming the form of the entropic dark energy as arises form the surface term in the Einstein-Hilbert's action, it's evolution were analyzed in an expanding flat universe. The model parameters were evaluated by constraining model using the Union data on Type Ia supernovae. We found that the model predicts an early decelerated phase and a later accelerated phase at the background level. The evolution of the Hubble parameter, dark energy density, equation of state parameter and deceleration parameter were obtained. The model is diagnosed with $Om$ parameter. The model is hardly seems to be supporting the linear perturbation growth for the structure formation. We also found that the entropic dark energy shows phantom nature for redshifts $z<0.257.$ During the phantom epoch, the model predicts big-rip effect at which both the scale factor of expansion and the dark energy density become infinitely large and the big rip time is found to be around 36 Giga Years from now.
description: 14 pages, 8 figures
(103375) Reginald Ridley Litchfield Gosling
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: The role of radiology in body identification and in determination of the cause of death in shipwrecked refugee casualties
Creators: name: Lo Re, Giuseppe
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Forensic / Necropsy studies
subject: CT
subject: Ethics
subject: Diagnostic procedure
subject: Computer Applications-Detection, diagnosis
subject: Forensics

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: In April 2015 an overcrowded boat with an estimated 700 migrants drowned off the Libyan coasts. It was the deadliest migrants Mediterranean shipwreck disaster of the present period. The Italian navy recovered the boat and thanks to a "Memorandum of...
Spatially Resolved Detection of a Spin-Entanglement Wave in a Bose-Hubbard Chain
Creators: name: Fukuhara, Takeshi
name: Hild, Sebastian
name: Zeiher, Johannes
name: Schauß, Peter
name: Bloch, Immanuel
name: Endres, Manuel
name: Gross, Christian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Entanglement is an essential property of quantum many-body systems. However, its local detection is challenging and was so far limited to spin degrees of freedom in ion chains. Here we measure entanglement between the spins of atoms located on two lattice sites in a one-dimensional Bose-Hubbard chain which features both local spin- and particle-number fluctuations. Starting with an initially localized spin impurity, we observe an outwards propagating entanglement wave and show quantitatively how entanglement in the spin sector rapidly decreases with increasing particle-number fluctuations in the chain.
description: 6 pages, 4 figures
Constraint Lie algebra and local physical Hamiltonian for a generic 2D dilatonic model
Creators: name: Corichi, Alejandro
name: Karami, Asieh
name: Rastgoo, Saeed
name: Vukašinac, Tatjana
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider a class of two dimensional dilatonic models, and revisit them from the perspective of a new set of "polar type" variables. These are motivated by recently defined variables within the spherically symmetric sector of 4D general relativity. We show that for a large class of dilatonic models, including the case \emph{with} matter, one can perform a series of canonical transformations in such a way that the Poisson algebra of the constraints becomes a Lie algebra. Furthermore, we construct Dirac observables and a reduced Hamiltonian that accounts for the time evolution of the system. Thus, with our formulation, the systems under consideration are amenable to be quantized with loop quantization methods.
description: 24 pages, 3 appendices. A few small changes applied to the text, including the addition of important new comments about rescalings on the Killing horizon. 3 new references added
title: Associating MRI findings of adhesive capsulitis with the clinical orthopedic exam
Creators: name: Ho, Corey
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Musculoskeletal system
subject: Musculoskeletal joint
subject: MR
subject: Education
subject: Inflammation

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Background According to the American Shoulder and Elbow Surgeons, adhesive capsulitis is a “condition of uncertain etiology characterized by significant restriction of both active and passive shoulder motion that occurs in the absence of a known...
DG Poisson algebra and its universal enveloping algebra
Creators: name: Lu, Jiafeng
name: Wang, Xingting
name: Zhuang, Guangbin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: In this paper, we introduce the notions of differential graded (DG) Poisson algebra and DG Poisson module. Let $A$ be any DG Poisson algebra. We construct the universal enveloping algebra of $A$ explicitly, which is denoted by $A^{ue}$. We show that $A^{ue}$ has a natural DG algebra structure and it satisfies certain universal property. As a consequence of the universal property, it is proved that the category of DG Poisson modules over $A$ is isomorphic to the category of DG modules over $A^{ue}$. Furthermore, we prove that the notion of universal enveloping algebra $A^{ue}$ is well-behaved under opposite algebra and tensor product of DG Poisson algebras. Practical examples of DG Poisson algebras are given throughout the paper including those arising from differential geometry and homological algebra.
description: Accepted by Science China Mathematics
title: Portal vein malignant thrombus recanalisation by endoportal RFA with metal stent placement (VesOpen procedure): rationale, technique and application
Creators: name: Mizandari, Malkhaz
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Interventional vascular
subject: Liver
subject: Veins / Vena cava
subject: Fluoroscopy
subject: Ultrasound-Colour Doppler
subject: Ablation procedures
subject: Stents

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: PV angioplasty by balloon dilatation and stenting is accepted low-invasive technique for recanalization of portal vein strictures, caused by pancreatic and biliary neoplasms (1,2,5,7), benign stenosis (3,4), postsurgery complications (6). We elected...
(103377) Margaret Ethel Perham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Pertinence of the micro-dose biplanar radiographs in children's pangonometry
Creators: name: Tillaux, Celine
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Paediatric
subject: Musculoskeletal system
subject: Radioprotection / Radiation dose
subject: Conventional radiography
subject: Image manipulation / Reconstruction
subject: Dosimetry
subject: Dosimetric comparison

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The aim of our study is to evaluate the dose and reliability of 2D lower limb measurements in childrens using micro-dose in comparison to low-dose biplanar...