cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Two representatives of lamiaceae essential oils and their main components cause changes in glutathione related enzymatic activities
Creators: name: Vašková, Janka
name: De Martino, Laura
name: Caputo, Lucia
name: De Feo, Vincenzo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plant Biology

description: Lavandula angustifolia Mill. (lavender) and Origanum heracleoticum L. (greek oregano) are aromatic plants used in traditional medicine for relief of convulsion, anxiety, insomnia and in the treatment of neurological disorders. On the basis of literature, we evaluated the changing in glutathione enzymatic activities provoked by the essential oils and pure components, linalool, carvacrol and limonene to study the mechanisms of action, responsible for several activities. Activities of SOD (superoxide dismutase) and GPx (glutathione peroxidase) tend to increase respect to control. SOD maximal increase reached up to 117% for carvacrol and limonene. Increase in GPx activity reached even up to value 1.229 for origanum oil in comparison to control 0.125 μkat/mg prot. Activities of GR (glutathione reductase), except for lavender, showed a biphasic response. Like for GR, the administration of compounds, resulted in a biphasic response in GST (glutathione-S-transferase) activities (with a consistent increase in activity at concentration 125 μg/mL for all compounds except lavender). Moreover, the changes in GSH (reduced glutathione), are no significant for different concentrations of essential oils. So, the biological properties of essential oils and specifically, the antioxidant ones, can be related to their capacity to modify the glutathione enzymatic activities.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.09.1968, erstellt von Emilia Tifrea, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Capture of BCR-ABL for Induction of Apoptosis in Chronic Myelogenous Leukemia: From Inhibition to Nuclear Escort
Creators: name: Dixon, Andrew S.
Publisher: name: University of Utah
Year: 2014

description: The primary cause of chronic myelogenous leukemia (CML) is the presence of the Philadelphia chromosome, resulting in the oncoprotein Bcr-Abl. The constitutive tyrosine kinase activity of Bcr-Abl, localized intracellularly in the cytoplasm, activates numerous oncogenic signaling pathways. Conversely, Bcr-Abl trapped in the cell nucleus induces apoptosis. This work is aimed at turning the oncogenic Bcr-Abl signaling into apoptotic signaling through redirecting Bcr-Abl, found only in the cancerous cells, to the nucleus. First, this work validated that Bcr-Abl could be directed to the nucleus with nuclear localization signals, and that nuclear Bcr-Abl does induce apoptosis. Ectopic expression of a nuclear localized Bcr-Abl construct in CML cells activated apoptotic signaling. Next, this worked focused on the design and isolation of Bcr-Abl binding domains. The first approach was the rational design of the Bcr-Abl coiled-coil domain which led to identification of mutations that could be made to enhance the oligomerization properties with Bcr-Abl. A nuclear translocation assay was then developed for studying protein interactions inside a live cell, and confirmed the modifications to the coiled-coil domain improved the binding to the wild-type coiled-coil domain representative of Bcr-Abl. In addition to the application to translocating Bcr-Abl iv to the nucleus, the improved oligomerization domain (CCmut2) was found to function as an inhibitor of Bcr-Abl. A second generation modification to the Bcr-Abl coiled-coil domain, CCmut3, was found to exhibit even greater binding than CCmut2 and also inhibited Bcr-Abl. As an alternative binding approach we used the intracellular antibody capture (IAC) methodology to isolate single domain antibodies (iDabs). Two Bcr-Abl regions with potential implications in the cytoplasmic retention of Bcr-Abl were targeted in the iDabs screens, the actin binding domain and Dbl homology/Pleckstrin homology domains. These screens produced ABI7, and when co-expressed with Bcr-Abl, caused a redistribution of the normal Bcr-Abl localization pattern. Both CCmut3 and ABI7 were tested for their ability to translocate Bcr-Abl into the nucleus and together were found to efficiently redirect Bcr-Abl to the nucleus. The culmination of this work is an established method to efficiently redirect Bcr-Abl from the cytoplasm into the nucleus where it is known to induce apoptosis.
Sonnenfleckenzeichnung Nr. 22900.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.09.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.09.1968, erstellt von Ahmet Topalbekiroglu an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
UPLC–QTOF–MS analysis of cytotoxic and antibacterial extracts of Hechtia glomerata Zucc
Creators: name: Stefani, Tommaso
name: Del C. Morales-San Claudio, Pilar
name: Rios, María Yolanda
name: Aguilar-Guadarrama, A. Berenice
name: González-Maya, Leticia
name: Sánchez-Carranza, Jessica Nayelli
name: González-Ferrara, Maurcio
name: del Rayo Camacho-Corona, María
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Hechtia glomerata, a Mexican medicinal plant employed against bacterial infections and as food, is taxonomically related to the genus Tillandsia which has anticancer activity. Organic and aqueous extracts of H. glomerata leaves were prepared and tested for cytotoxic and antibacterial activity. UPLC–QTOF–MS analysis determined the chemical composition of active extracts to find cytotoxic and antibacterial compounds. Hexane extract was cytotoxic against HepG2, Hep3B and MCF7 (IC50: 24–28 µg/mL), whereas CHCl3/MeOH extract against PC3 and MCF7 (IC50: 25 and 32 µg/mL). CHCl3/MeOH extract showed antibacterial activity against Staphylococcus aureus and Enterococcus faecium (MIC: 125 and 62.5 µg/mL). Hexane extract cytotoxic compounds were β-sitosterol, stigmasterol, phytol and ursolic acid. CHCl3/MeOH extract antibacterial and/or cytotoxic compounds were daucosterol, oleanolic acid, resveratrol, quercetin, kaempferol, apigenin, cyanidin, p-coumaric acid and caffeic acid. This plant could be useful against bacterial infections and cancer. However, in vivo studies are needed to determine its toxicity and therapeutic efficacy.
Molecular genetics of Williams syndrome
Creators: name: Toland, Amanda Ewart
Publisher: name: University of Utah
Year: 2012
Subjects: Mental Disabilities

description: Williams syndrome (WS) is a developmental disorder characterized by cardiovascular disease, connective tissue abnormalities, unique personality, specific cognitive profile, mental retardation, and infantile hypercalcemia.  Over the past five years, our laboratory discovered that submicroscopic deletions of chromosome 7q11.23 cause WS and demonstrated the hemizygosity of two genes, elastin (ELN) and LIM-kinase (LILMK), is important for the WS phenotype.  My contribution to these discoveries includes the following:  mapping the locus for autosomal dominant supravalvular aortic stenosis (SVAS) to chromosome 7q11.23; identifying linkage between SVAS and ELN in two kindreds; demonstrating by Southern analyses that an SVAS-associated translocation disrupts ELN in a third kindred; identifying a ~90 kb SVAS-associated deletion in the 3' end of ELN in another kindred; demonstrating by dosage and genotype analyses that WS is caused by a submicroscopic deletion of chromosome 7q11.23 including one ELN allele; completing the characterization of the genomic structure of ELN for addition mutational analysis; and contributing to the finding that deletions of a second gene,  LIMK are associated with specific cognitive profile of WS.  These results provide the first molecular insight into the development of human cognitive function and the pathophysiology of ELN in vascular disease.  Furthermore, these studies will facilitate future work deciphering the molecular basis of WS.
The Psychological Burden of the COVID-19 Pandemic and Its Associated Factors among the Frontline Doctors of Bangladesh: A Cross-sectional Study-STROBE checklist
Creators: name: Barua, Lingkan
name: Zaman, Muhammed Shahriar
name: Omi, Fardina Rahman
name: Faruque, Mithila
Publisher: name: Zenodo
Year: 2020
Subjects: STROBE, COVID-19, Bangladesh, Frontline doctors, Mental health

description: We used the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines for reporting the results of the cross-sectional observational study.
Effectiveness of a brief stress reduction intervention for nursing students in reducing physiological stress indicators and improving well-being and mental health
Creators: name: Leggett, Diane K.
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Depression
subject: Mindfulness
subject: Nursing
subject: FOS: Health sciences
subject: Self-efficacy
subject: Stress
subject: Students
subject: Stress reduction intervention

description: Nursing students are faced with stress on a regular basis, which can impact physical and psychological functioning. Despite the identification of stress, anxiety, poor performance, and risk for depression, few studies identify measures to manage stress in a student nurse population. The purpose of this study was to examine the effectiveness of a brief mindfulness breathing intervention to decrease stress and ultimately the risk for depression while increasing self-efficacy with clinical skills performance in a 1st-year student nurse population.  Participants were recruited from an associate degree nursing program at a northwestern university. Data gathered included demographic information, depression scores, physiological measures (i.e., blood pressure and pulse), self-efficacy scores, and skills performance scores. The design was a two-group (experimental and no-treatment control) true experimental randomized control trial with the following four repeated measures: (a) pretest, (b) posttest, (c) 2-month follow-up test, and (d) 4-month follow-up test. Data collection took place from November 2009 to March 2010. The sample (N = 85) was predominantly female (87.1%, n = 74) and Caucasian (89.4%, n = 86). Fifty-six of the participants were married and 46% of the participants identified themselves as parents of children still living at home.  Analyses of variance demonstrated a greater mean decrease for the intervention group than for the treatment-as-usual group following the mindfulness breathing intervention for depression, F(1,82) = 6.864, p = .010; systolic, F(1,81) = 6.557, p = .012; and diastolic, F(1,81) = 6.078, p = .016-measures indicating the intervention may be of benefit. Pulse did not reach statistical significance. Analyses of variance for mindfulness, self-efficacy, and skills performance did not reach significance. Correlations conducted on measures indicated that as depression decreased, systolic and diastolic measures also decreased. As mindfulness increased, self-efficacy increased, and as self-efficacy increased, skills performance also increased. These results suggest that mindfulness may be of benefit as a method to decrease the risk for depression while contributing to increased self-efficacy and skills performance in a student nurse population. Although not all measures achieved statistical significance, the findings are encouraging for increasing feelings of confidence, leading to a more rewarding educational experience in nursing students
Callistethus virescens
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Callistethus
Callistethus virescens

description: Callistethus virescens (Burmeister, 1844)
Anomala (Spilota) virescens Burmeister 1844: 268 (French Guiana)
= Anomala demerarae Ohaus 1897: 423 (Guyana)
Distribution. Guyana: Ohaus 1897: 423 (as Anomala demerarae); Machatschke 1972: 175. French Guiana: Burmeister 1844: 268 (as Anomala virescens); Machatschke 1972: 175; Soula 2010a: 53. “Guianas”: Blackwelder 1944: 245 (as Anomala virescens).
Note. Soula (2010a: 53) mentions Callistethus virescens as “doubtful or to be confirmed” for French Guiana because it is, according to him, described from “ Guyana.” In fact, this species is described from French Guiana, whereas its synonym, Anomala demerarae, is described from Guyana in Ohaus (1897: 423).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 121, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung Nr. 22907.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.09.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Fotografische Sonnenaufnahme und zugehörige Zeichnung, unnummeriert.
Fotoabzug und durchgepauste Zeichnung der Aufnahme von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.09.1968, fotografiert von John S. Korintus
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Der Abzug ist auf der Rückseite mit genauen Angaben versehen. Flecken und Fackelflächen sind auf das Pauspapier übertragen. Im Jahresbericht für das vorliegende Jahr ist John S. Korintus nicht erwähnt
Strigoderma Burmeister 1844
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Strigoderma

description: STRIGODERMA Burmeister, 1844
Strigoderma Burmeister 1844: 310
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 121, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.11.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Completeness and accuracy of the registration of recurrences in the Swedish Colorectal Cancer Registry (SCRCR) and an update of recurrence risk in colon cancer
Creators: name: Osterman, Erik
name: Hammarström, Klara
name: Imam, Israa
name: Osterlund, Emerik
name: Sjöblom, Tobias
name: Glimelius, Bengt
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: The completeness and accuracy of the registration of synchronous metastases and recurrences in the Swedish Colorectal Cancer Registry has not been investigated. Knowing how accurate these parameters are in the registry is a prerequisite to adequately measure the current recurrence risk. All charts for patients diagnosed with stage I–III colorectal cancer (CRC) in two regions were reviewed. In one of the regions, all registrations of synchronous metastases were similarly investigated. After the database had been corrected, recurrence risk in colon cancer was calculated stratified by risk group as suggested by ESMO in 2020. In patients operated upon more than five years ago (N = 1235), there were 20 (1.6%) recurrences not reported. In more recent patients, more recurrences were unreported (4.0%). Few synchronous metastases were wrongly registered (3.6%) and, likewise, few synchronous metastases were not registered (about 1%). The five-year recurrence risk in stage II was 6% for low-risk, 11% for intermediate risk, and 23% for high-risk colon cancer patients. In stage III, it was 25% in low- and 45% in high-risk patients. Incorporation of risk factors in stage III modified the risks substantially even if this is not considered by ESMO. Adjuvant chemotherapy lowered the risk in stage III but not to any relevant extent in stage II. The registration of recurrences in the registry after 5 years is accurate to between 1 and 2% but less accurate earlier. A small number of unreported recurrences and falsely reported recurrences were discovered in the chart review. The recurrence risk in this validated and updated patient series matches what has been recently reported, except for the risk of recurrence in stage II low risk colon cancers which seem to be even a few percentage points lower (6 vs. 9%).
Strigoderma marginata
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Strigoderma
Strigoderma marginata

description: § Strigoderma marginata (Olivier, 1789)
Melolontha marginata Olivier 1789: 70 (Guadeloupe)
= Strigoderma aenea Blanchard 1851: 202 (Bolivia)
Distribution. French Guiana: Blanchard 1851: 202. Brazil: Blackwelder 1944: 246; Machatschke 1972: 220; Bader 1992: 279. Venezuela: Blanchard 1851: 202; Bader 1992: 279. Other: Olivier 1789: 70 (Guadeloupe - as Melolontha marginata); Blanchard 1851: 202 (Bolivia - as S. aenea; Bolivia - as S. marginata); Blackwelder 1944: 245, 246 (Bolivia - as S. aenea; Argentina, Guadeloupe, Mexico, Panama - as S. marginata); Machatschke 1972: 220 (Argentina–Mexico, Bolivia, Guadeloupe); Bader 1992: 279 (Costa Rica, Nicaragua, Panama, Peru).
Note 1. Blanchard (1851: 202) mentions Strigoderma marginata for Cayenne [= French Guiana], but we are unaware of any other records from the research area. We assume that Blanchard’s record is based on a mislabeled or misidentified specimen and regard this species as not occurring in the research area.
Note 2. See the first note at Callistethus marginatus for a comment on the specific epithet of Strigoderma marginata.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 122, DOI: 10.5281/zenodo.3678492
Glutaminase inhibitory activity of umbelliferone isolated from kabosu (Citrus sphaerocarpa Hort. ex Tanaka)
Creators: name: Shimada, Atsumi
name: Ueno, Hiroshi
name: Inagaki, Masanori
name: Yoshimitsu, Hitoshi
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Kabosu (Citrus sphaerocarpa Hort. ex Tanaka) fruits have pleasant and fresh odors and have been used as raw materials for vinegar, seasonings, jams, marmalades and juices in Japan. The n-butanol extracts from kabosu fruits were prepared and a component in the extract was purified by column chromatography and HPLC to afford compounds 1-3. Three compounds, 5-(hydroxymethyl)-2-furaldehyde (1), umbelliferone (2) and oxypeucedanin hydrate (3), have been isolated from kabosu, and the structures of compounds 1-3 were elucidated by 1 D and 2 D NMR as well as EI-MS. Compound 2 exhibited potent glutaminase inhibitory activity with an IC50 value of 1.33 mM. This is the first report on glutaminase inhibitory activity of 2 and the isolation of three compounds 1-3 from kabosu fruits.
Drug modification of chloride transport in the choroid plexus- cerebrospinal fluid system of the rat
Creators: name: Quan-Sheng, Deng
Publisher: name: University of Utah
Year: 2012
Subjects: Chlorides in the body
Cerebrospinal fluid

description: The mechanisms of anion and cation transport in the choroid plexus-cerebrospinal fluid (CP-CSF) system are a part of the blood-brain barrier system which provides a homeostatically regulated environment for the brain. The characteristics of CI transport in the CP-CSF system have been investigated both in vivo and in vitro. The following hypotheses have been tested in these studies: 1) that the primary carrier mechanism for CI transport in the CP is the CI-HCO3 antiport system which exists at both poles of the epithelial cell; and 2) that CI transport plays an important role in the CSF secretory process.  The disulfonic stilbene (DIDS), a specific inhibitor of CI-HCO-3 exchange, was used to study the location and the mechanism of CI transport. Sprague-Dawley rats were used in all studies. Animals were nephrectomized under ether anesthesia and ketamine (80 mg/kg) was administered prior to placement of the animal in the stereotaxic instrument. Drugs were injected into the left lateral ventricle, and 36-Cl and 22-Na (100 microcuries/kg) were administered intraperitoneally (IP.) 30 min after drug treatment. The ventriculo-cistemal perfusion technique was used to measure the rate of formation of CSF during the control and drug treatment (DIDS and PGE2) periods. The quantity of 36-Cl and 22-Na in CSF, medulla and CPs was expressed as the percent of the tissue volume that would be occupied by the radioactivity if it existed at the same concentration as in the plasma water, i.e., Vd = 100 X (dpm/g tissue / dpm/g plasma H-2-O). Tissue electrolytes were extracted into a 0.02 N HNO-3-O.OI5 N Li solution and Na and K were measured by flame photometry.  The results suggest that: 1) the CI-HCO-3 transport systems exist on both sides of the epithelial membrane of the CP; 2) DIDS inhibits CI and Na transport in the CP-CSF system; 3) as a result of inhibition of both CI and Na transport by DEDS, the rate of formation of CSF is decreased; and 4) PGE-2 stimulates the entry of CI into both CP and CSF which may account for its effect to increase the rate of formation of CSF. These observations support the hypothesis that CI transport may be one of the driving forces of CSF formation.
CAP After 2004: Policy to Promote Development or to Elimination Differences Between Regions? Non-parametric Approach Based on Farm Efficiency in the Old and New EU Regions
Creators: name: Błażejczyk-Majka, Lucyna
name: Błażejczyk-Majka, Lucyna
Publisher: name: Unknown
Year: 2022
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: EU cohesion policy
subject: Common Agricultural Policy
subject: supper-efficiency model
subject: DEA

description: In the light of the Treaty establishing the European Economic Community (Treaty of Rome) of 25 March 1957, the primary aim of the Common Agricultural Policy is to provide European Economic Community citizens with adequate amounts of food at reasonable prices and to guarantee farmers a decent standard of living. That is more, the EU fund transfers were to eliminate differences between regions and promote development of individual regions. These aims proved to be particularly important following the EU enlargement in 2004. The indispensible effect of the integration process has been connected with changes in the directions of agricultural production and efficiency of utilisation of individual inputs. Nevertheless, it is difficult to evaluate the effects of the implemented policy based on univariate comparisons. In view of the above, the aim of this paper is to assess the effects of the agricultural policy and the cohesion policy implemented in the EU, focusing on the valuation of the impact of the greatest EU enlargement on this relationship. This goal was achieved thanks to constructing multivariate rankings applying the DEA super-efficiency model for average farms specialising in plant, animal and mixed production in individual EU member countries for two period. The application of the DEA efficiency model makes it possible in the computation process to take into consideration the fact that in the course of agricultural production three groups of products are manufactured involving four basic types of inputs. The starting point for the analyses was provided by data published within the FADN agenda for average farms operating in the countries being the EU members. The results showed that after the largest enlargement of the EU, in the case of plant and livestock production, a simultaneous increase in agricultural production and improvement in efficiency in the individual EU members was achieved, with a gradual reduction of disproportions in the efficiency of agricultural production between regions. The only area where such a relationship could not be observed was related to the production of mixed-type farms. The novelty of the proposed in this article approach is that it allows for simultaneous analysing of changes in EU agriculture while taking into account several perspectives: changes in the assumptions of the common agricultural policy, the consequences of EU enlargement, and results of the implementation of the cohesion policy.
Relationship between housing and health
Creators: name: Makhaye, Nelisile Rosemary
Publisher: name: University of Utah
Year: 2012
Subjects: South Africa

description: The primary concerns of this paper are threefold:  to explore the possible relationship between housing conditions and health, to determine how much people know about personal hygiene, and to identify what the people from the squatter areas need in order to uplift their standard of living.  A survey was undertaken covering 150 households in three different housing areas.  Associations were established between crowding and a number of health indices and between sanitation and sanitary facilities.  The difficulties of determining the effects of housing conditions per se, of other environmental circumstances, and of factors such as economic status, adequacy of medical care and nutrition are also discussed.  The findings of this study show that there is a positive relationship between housing conditions and health and that there is a need for constructive policies.
Chemical composition and antioxidant activity of the essential oil of Alseodaphne velutina Chev. from Viet Nam
Creators: name: Cuong, Nguyen Tien
name: Ban, Pham Hong
name: Van Chung, Mai
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: Chemical composition and antioxidant activity of the essential oil of Alseodaphne velutina Chev. (Lauraceae) were investigated for the first time from Viet Nam. Leaf essential oil was hydrodistilled and analysed by GC and GC-MS that totally identified 32 terpenoid compounds (accouting for 89.18% of the total oil) with β-patchoulene (25.74%) and β-caryophyllene (12.81%) as two major sesquiterpene hydrocarbons compounds. The antioxidant potential of leaf essential oil was evaluated using DPPH, ABTS and FRAP assays, and revealed a moderate-to-high activity comparable with already known antioxidant standard Trolox.
Analysis of state public employee retirement systems (PERS): governance network complexity, capacity, accountability and legitimacy
Creators: name: Franco, Heidi Hicks
Publisher: name: University of Utah
Year: 2012
Subjects: Governance
Governance networks
Pension plans
PERS
Privatization
State and local government

description: State government Public Employee Retirement Systems (PERS) are studied extensively in Economic and Financial literature regarding their history, fund solvency, management standards and governance practices; yet research in State PERS is relatively new in Political Science;. State PERS‘ funds are generated from taxpayer, employee contributions, and investment earnings and are accruing immense liabilities for the future. All State PERS are dependent on one of the largest privatization movements at the state level-the privatization of their fund management through financial professionals. State pension funds rely on global private markets for investment returns to provide beneficiary pension payments. Given State PERS‘ impact on the global economy, state taxpayer liabilities, and the continuing effects of the 2008-2009 "Great Recession,"  Political Science; must further investigate State PERS to understand the complexities of their policymaking dynamics. How are State PERS managed? This dissertation explains the pressures and concerns in their policymaking environment. Ultimately it shows how State PERS meet the standards of governance capacity, accountability and legitimacy within their governance networks.
Sonnenfleckenzeichnung Nr. 22880.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.08.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Automated screening of metabolic disorders using pattern recognition of GC-MS full scan spectra from urine organic acids
Creators: name: Crockett, David K.
Publisher: name: University of Utah
Year: 2012
Subjects: Metabolism Errors
Fatty Acid Oxidation Disorders
Urine Organic Acids

description: Analysis of organic acids in urine is a valuable tool in the diagnosis of the inborn errors of metabolism known as organic acidurias.  This test is commonly ordered in newborns with symptoms such as lethargy, failure to thrive, hepatic failure, and suspected familial disorders.  A drawback of published methods is the overwhelming amount of data to examine for each patient, prior to the final laboratory report.  Physicians will wait as long as two weeks for these time critical results.  The goal of this research was to develop and export system to automate the process of screening for metabolic disorders of urine organic acids.  The Xaminer® pattern recognition software (ThermoFinnigan, San Jose, CA) was adapted to predict and identify patterns of urine organic acid disorders.  The gas chromatography-mass spectrometry (GC-MS) full scan spectra of organic acids were used to build the pattern match library and train the software to recognized methylmalonic aciduria (MMA) and associated vitamin B12 deficiency, as well as, a subset of fatty acid oxidation defects (FAOD), including medium chain acyl-CoA dehydrogenase (MCAD) deficiency.  Patient data files were de-identified and reprocessed using the expert system.  The expert system results were compared to the original laboratory findings.  From a total of 2573 samples, the original laboratory findings were 20 positives for MMA and 29 positives for FAOD.  The Xaminer software identified 17 of the 20 MMA positives, plus 4 additional candidate samples that matched the search pattern criteria.  The software found 26 of the 29 FAOD positives.  Five additional samplers found to be candidates for FAOD.  Software analysis time averaged less than 10 seconds per sample.  This expert system can use pattern recognition of full scan GC-MS data to aid in patient screening for MMA and fatty acid oxidation disorders.  The performance of Xaminer shows promise for refining or expanding the reference library to include other metabolic disorders as well.
Strigoderma Burmeister 1844
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Rutelidae
Strigoderma

description: Strigoderma sp.
Distribution. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Sipaliwini, Puketi, (4°07′30″N, 54°37′30″W). 14/ 18-VII-2013. A. J. Hielkema. On UV/HPL in open area.).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 122, DOI: 10.5281/zenodo.3678492
Random geometric graphs and data structures: discrete estimations of the continuous
Creators: name: De Kergorlay, Henry-Louis Melchior
Publisher: name: The University of Edinburgh
Year: 2020
Subjects: data sets
Topological Data Analysis
Cheeger consistency
Morse theory
spectral clustering

description: In recent years, there have been significant efforts to develop rigourous geometric and topological methodologies to better understand data sets, with the view of performing machine learning tasks such as spectral clustering, non-linear dimensionality reduction and Topological Data Analysis. These methodologies have various objectives, use different techniques and are fundamentally different. For instance, the techniques used to tackle the consistency of spectral clustering or Cheeger consistency which are also discussed in this thesis, follow the so-called variational approach (proposed by Trillos and Slepcev in a series of works, initiated in [63]). On the other hand, techniques used to investigate topological features of random geometric complexes usually require knowledge of different fields such as Morse theory. While these methodologies are fundamentally different, they may be related through the concept of random geometric graphs. On the one hand, problems such as spectral clustering and Cheeger consistency can be seen as optimisation problems on functionals defined on random geometric graphs. On the other hand, random geometric complexes can be thought as generalisations of random geometric graphs, where we not only take into consideration vertices and edges, but also higher order simplices. Another common point is that all these methodologies are attempts to capture various geometric invariants of a manifold from an underlying sampled set of i.i.d. points (e.g., Betti numbers, Cheeger constants, spectrum of the Laplacian). While these methodologies have been applied successfully, there is still a lack of results providing theoretical guarantees and rigorously explaining the extent to which these various frameworks effectively work, under various settings. The aim of this thesis is to contribute to the development of such theoretical guarantees, building on existing results and methods.
Bacteriological survey of wound infections in Benin city, Nigeria
Creators: name: Ifeoma Enweani
Publisher: name: figshare
Year: 2020
Subjects: subject: 110801 Medical Bacteriology
subject: FOS: Health sciences

description: The bacterial aetiology of wound infections in a large, urban referral hospital was studied over a sixmonth period. Of a total of 150 patients used for this study, a very high rate of infected wounds (62%)was recorded. There was no significant difference in the incidence of infected wounds among males andfemales (P>0.001) but a notable variation in incidence was observed among different age groups withvery high rates of wound infections occurring among the elderly (75%) and infants (66.6%) at P>0.001.predominant bacteria isolated include Staphylococcus aureus (40.7%), Pseudomonas aeruginosa (17.8%),Proteus mirabilis (12.7%) and Escherichia coli 911.0%). The antibiotic sensitivity profile showed that thequinolone drugs (ofloxacin, pefloxacin and ciprofloxacin) are more potent against the isolated pathogenswhile there was high resistance to penicillin G, ampicillin and erythromycin. Appropriate practical meansof improving wounds management and therapy are advocated.
Fotografische Sonnenaufnahme und zugehörige Zeichnung, unnummeriert, einen Zürcher Lückentag ergänzend.
Fotoabzug und durchgepauste Zeichnung der Aufnahme von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.09.1968, fotografiert von John S. Korintus
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Der Abzug ist auf der Rückseite mit genauen Angaben versehen. Flecken und Fackelflächen sind auf das Pauspapier übertragen. Im Jahresbericht für das vorliegende Jahr ist John S. Korintus nicht erwähnt
Sonnenfleckenzeichnung Nr. 22934.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.10.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.09.1968, erstellt am Sonnenobservatorium der Universität Teheran
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Zeichnung von Sonnenflecken (Bleistift und Farbstift), erstellt als Projektionsbildzeichnung in Teheran.
Unter Umständen im Zusammenhang mit Beobachtungen des Air Weather Service der U.S. Air Force im Auftrag des NASA Controll Centers in Houston erstellt. Instrument: unbekannt.
Instrument unbekannt
Surface local field potentials for brain-computer interfaces
Creators: name: Kellis, Spencer Sterling
Publisher: name: University of Utah
Year: 2012
Subjects: Electrocorticography
Human
Micro-ECoG
Neural prosthetics
Signal processing
Speech decode
Brain-computer interfaces

description: This dissertation describes the use of cortical surface potentials, recorded with dense grids of microelectrodes, for brain-computer interfaces (BCIs). The work presented herein is an in-depth treatment of a broad and interdisciplinary topic, covering issues from electronics to electrodes, signals, and applications.  Within the scope of this dissertation are several significant contributions. First, this work was the first to demonstrate that speech and arm movements could be decoded from surface local field potentials (LFPs) recorded in human subjects. Using surface LFPs recorded over face-motor cortex and Wernickes area, 150 trials comprising vocalized articulations of ten different words were classified on a trial-by-trial basis with 86% accuracy. Surface LFPs recorded over the hand and arm area of motor cortex were used to decode continuous hand movements, with correlation of 0.54 between the actual and predicted position over 70 seconds of movement.  Second, this work is the first to make a detailed comparison of cortical field potentials recorded intracortically with microelectrodes and at the cortical surface with both micro- and macroelectrodes. Whereas coherence in macroelectrocorticography (ECoG) decayed to half its maximum at 5.1 mm separation in high frequencies, spatial constants of micro-ECoG signals were 530-700 ?m-much closer to the 110-160 ?m calculated for intracortical field potentials than to the macro-ECoG. These findings confirm that cortical surface potentials contain millimeter-scale dynamics. Moreover, these fine spatiotemporal features were important for the performance of speech and arm movement decoding.  In addition to contributions in the areas of signals and applications, this dissertation includes a full characterization of the microelectrodes as well as collaborative work in which a custom, low-power microcontroller, with features optimized for biomedical implants, was taped out, fabricated in 65 nm CMOS technology, and tested. A new instruction was implemented in this microcontroller which reduced energy consumption when moving large amounts of data into memory by as much as 44%.  This dissertation represents a comprehensive investigation of surface LFPs as an interfacing medium between man and machine. The nature of this work, in both the breadth of topics and depth of interdisciplinary effort, demonstrates an important and developing branch of engineering.
Solvent-free microwave extraction: an eco-friendly and rapid process for green isolation of essential oil from lemongrass
Creators: name: Boukhatem, Mohamed Nadjib
name: Ferhat, Mohamed Amine
name: Rajabi, Mehdi
name: Mousa, Shaker A.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: The extraction of lemongrass essential oil (LGEO) using large quantities of solvents makes this extraction a hazardous and environmentally unfriendly procedure. Our aim was to find a suitable method for the improvement of its extraction and its quality. Solvent-Free Microwave Extraction (SFME) is a combination of dry distillation and microwave heating. SFME of LGEO was compared with conventional extraction hydrodistillation (HD). SFME is quicker than conventional HD. An extraction time of 15 min with SFME provided a yield of 0.6% comparable with that obtained after 120 min using HD. The composition of these oils revealed that the main components obtained with HD and SFME were both geranial (59.93% vs 44.59%, respectively). The quality of lemongrass is determined by its citral content, and a higher amount of citral was present in SFME oil (74%) in comparison with HD oil (60%). SFME is a green and a promising technology for the extraction of essential oils.
Sonnenfleckenzeichnung Nr. 22944.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.11.1968, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Geniatini Burmeister 1844
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae

description: GENIATINI Burmeister, 1844
Synopsis. Jameson and Hawkins 2005 (genera)
Catalogue. Jameson and Hawkins 2005
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 122, DOI: 10.5281/zenodo.3678492