cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Toxicological assessment of a prototype e-cigaret device and three flavor formulations: a 90-day inhalation study in rats
Creators: name: Werley, Michael S.
name: Kirkpatrick, Dan J.
name: Oldham, Michael J.
name: Jerome, Ann M.
name: Langston, Timothy B.
name: Lilly, Patrick D.
name: Smith, Donna C.
name: Mckinney, Willie J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: A prototype electronic cigaret device and three formulations were evaluated in a 90-day rat inhalation study followed by a 42-day recovery period. Animals were randomly assigned to groups for exposure to low-, mid- and high-dose levels of aerosols composed of vehicle (glycerin and propylene glycol mixture); vehicle and 2.0% nicotine; or vehicle, 2.0% nicotine and flavor mixture. Daily targeted aerosol total particulate matter (TPM) doses of 3.2, 9.6 and 32.0 mg/kg/day were achieved by exposure to 1 mg/L aerosol for 16, 48 and 160 min, respectively. Pre-study evaluations included indirect ophthalmoscopy, virology and bacteriological screening. Body weights, clinical observations and food consumption were monitored weekly. Plasma nicotine and cotinine and carboxyhemoglobin levels were measured at days 28 and 90. After days 28, 56 and 90, lung function measurements were obtained. Biological endpoints after 90-day exposure and 42-day recovery period included clinical pathology, urinalysis, bronchoalveolar fluid (BALF) analysis, necropsy and histopathology. Treatment-related effects following 90 days of exposure included changes in body weight, food consumption and respiratory rate. Dose-related decreases in thymus and spleen weights, and increased BALF lactate dehydrogenase, total protein, alveolar macrophages, neutrophils and lung weights were observed. Histopathology evaluations revealed sporadic increases in nasal section 1–4 epithelial hyperplasia and vacuolization. Following the recovery period, effects in the nose and BALF were persistent while other effects were resolved. The no observed effect level based upon body weight decreases is considered to be the mid-dose level for each formulation, equivalent to a daily TPM exposure dose of approximately 9.6 mg/kg/day.
Attention and memory bias to facial emotions underlying negative symptoms of schizophrenia
Creators: name: Seon-Kyeong Jang
name: Seon-Cheol Park
name: Seung-Hwan Lee
name: Cho, Yang Seok
name: Kee-Hong Choi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Introduction. This study assessed bias in selective attention to facial emotions in negative symptoms of schizophrenia and its influence on subsequent memory for facial emotions. Methods. Thirty people with schizophrenia who had high and low levels of negative symptoms (n = 15, respectively) and 21 healthy controls completed a visual probe detection task investigating selective attention bias (happy, sad, and angry faces randomly presented for 50, 500, or 1000 ms). A yes/no incidental facial memory task was then completed. Attention bias scores and recognition errors were calculated. Results. Those with high negative symptoms exhibited reduced attention to emotional faces relative to neutral faces; those with low negative symptoms showed the opposite pattern when faces were presented for 500 ms regardless of the valence. Compared to healthy controls, those with high negative symptoms made more errors for happy faces in the memory task. Reduced attention to emotional faces in the probe detection task was significantly associated with less pleasure and motivation and more recognition errors for happy faces in schizophrenia group only. Conclusions. Attention bias away from emotional information relatively early in the attentional process and associated diminished positive memory may relate to pathological mechanisms for negative symptoms.
title: 01_0124
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
EOSC-EVERSE: Paving the way towards a European Virtual Institute for Research Software Excellence
Creators: name: Psomopoulos, Fotis
name: Capella-Gutierrez, Salvador
name: Portell-Silva, Laura
name: Pechlivanis, Nikolaos
Publisher: name: Zenodo
Year: 2024
Subjects: research software
research software quality
software best practices
community building
EOSC Science Clusters
software recognition
sustainable research software
innovation

description: The EVERSE project aims to create a framework for research software and code excellence, collaboratively designed and championed by the research communities across five EOSC Science Clusters and national Research Software Expertise Centres, in pursuit of building a European network of Research Software Quality and setting the foundations of a future Virtual Institute for Research Software Excellence.

This framework for research software excellence will incorporate aspects involving community curation, quality assessment, and best practices for research software. This collective knowledge will be captured in the Research Software Quality toolkit (RSQkit), aknowledge base to gather and curate expertise that will contribute to high-quality software and code across different disciplines.

By embedding the RSQkit and services into the EOSC Science Clusters, EVERSE will demonstrate improvements in the quality ofresearch software and maximise its reuse, leading to standardised software development practices and sustainable research software. Furthermore, we will drive recognition of software and support career progress for developers, from researchers who code to RSEs, raising their capacity to guarantee software quality.

The European network for Research Software Quality aims to cross-fertilise different research domains, act as a lobbying organisation, and raise awareness of software as a key enabler in research, with the overall ambition to accelerate research and innovation through improving the quality of research software and code.

EVERSE ultimate ambition is to contribute towards a cultural change where research software is recognized as a first-class citizen ofthe scientific process and the people that contribute to it are credited for their efforts.

These slides were presented in the context of the ReSA Funders' Forum meeting (January 16th/17th 2024), as well as at the International Research Software Engineering Research (IRSER) Community Meetup (January 17th 2024, agenda here).
Sektionskonzept Training & Education zur Einrichtung einer Sektion im Verein Nationale Forschungsdateninfrastruktur (NFDI) e.V.
Creators: name: Herres-Pawlis, Sonja
name: Pelz, Peter
name: Kockmann, Norbert
name: Gläser, Roger
name: Richter, Manuela
name: Liermann, Johannes
name: Ortmeyer, Jochen
name: Heine, Ina
name: Metzmacher, Amelie
name: Andres, Ann-Christin
name: Münzmay, Andreas
name: Heuer, Jan-Ocko
name: Hagener, Malte
name: Dierkes, Jens
name: Wiljes, Cord
name: Lindstädt, Birte
name: Danabalan, Renita
name: Jolliffe, John D.
Publisher: name: Zenodo
Year: 2022

description: Sektionskonzept zur Einrichtung einer Sektion im Verein Nationale Forschungsdateninfrastruktur (NFDI) e.V. Name der Sektion: Training & Education Akronym der Sektion: section-edutrain Ansprechpersonen Sektionseinrichtung: Prof. Dr.-Ing Peter F. Pelz (NFDI4Ing), Prof. Dr. rer. nat. Sonja Herres-Pawlis (NFDI4Chem) Version: 2.0 Kurzbeschreibung: Datenkompetenz von Anfang an! Damit betonen wir erstens die Wichtigkeit von Bildung in Datenkompetenz aller Stakeholder in allen Bereichen der Forschung und der Hochschullehre. Zweitens zeigt unser Paradigma den Weg zur Nachhaltigkeit von Forschungsdatenmanagement (FDM). Durch “Datenkompetenz von Anfang an” tragen wir zur Weiterentwicklung wissenschaftlicher Methoden und der guten wissenschaftlichen Praxis bei: Bildung in Datenkompetenz ermöglicht, die formale Qualität der Ressource “Daten” so zu steigern, dass sie sowohl für Erkenntnis als auch für nachhaltige Lösungen gesellschaftlicher Herausforderungen genutzt werden kann. Dies geschieht durch Transparenz und Nachvollziehbarkeit für alle Stakeholder in einem offenen oder auch geschützten Datenraum...
Carnet nº 6, commencé à Irkoutsk (p. 4)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 5-1-1930
CODES-Quant_ Coherence-Driven Trading Architecture
Creators: name: Bostick, Devin
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Artificial Intelligence
subject: Monetary and finances
subject: Mathematics
subject: FOS: Mathematics
subject: Coherence-Based Trading
subject: CODES Framework
subject: Financial Signal Modeling

description: Paper to CODES Framework: Link

Abstract

This paper introduces CODES-Quant, the first trading architecture grounded in structured resonance rather than probabilistic modeling. Built on the Resonance Intelligence Core (RIC), the system uses prime-anchored harmonic functions (Cₙ), a real-time coherence metric (PAS), and a nonlinear memory engine (ELF) to detect alignment in market structure and guide execution based on phase integrity—not prediction.

Unlike traditional quant frameworks that optimize for expected value or volatility surfaces, CODES-Quant detects coherence events—moments when market behavior reflects deep structural resonance. The system includes CHORDLOCK, a multi-scale positioning module that locks trades only when macro-phase alignment is confirmed, and FlameCam, a visual overlay for human interpretability.

We demonstrate how this architecture outperforms probabilistic models across key market regimes—FOMC events, earnings traps, and macro rotations—by tuning to the field underneath price, not the noise surrounding it. With no training, no optimization, and no probabilistic assumptions, CODES-Quant redefines trading as resonance participation, not stochastic speculation.
Effect of the structure of dietary epoxylignan on its cytotoxic activity: relationship between the structure and the activity of 7,7′-epoxylignan and the introduction of apoptosis by caspase 3/7
Creators: name: Tuti Wukirsari
name: Nishiwaki, Hisashi
name: Nishi, Kosuke
name: Sugahara, Takuya
name: Akiyama, Koichi
name: Kishida, Taro
name: Yamauchi, Satoshi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: We compared the cytotoxic activities of dietary epoxylignans and their stereoisomers and found (−)-verrucosin, which is (7S,7′R,8R,8′R)-7,7′-epoxylignan, to be the most cytotoxic epoxylignan against HeLa cells (IC50 = 6.6 μM). On the other hand, the activity was about a factor of 10 less against HL-60. In this research on the relationship between the structure and cytotoxic activity of (−)-verrucosin 13, the 7-(4-methoxyphenyl)-7′-(3,4-dimethoxyphenyl) derivative 60, for which the activity (IC50 = 2.4 μM) is three times greater than (−)-verrucosin 13, was discovered. The induction of apoptosis by caspase 3/7 was observed upon treatment with the (−)-verrucosin derivative. 3′,4,4′-Trimethoxy-7,7′-epoxylignan showed highest IC50 value (2.4 μM) in this structure–cytotoxic activity relationship experiment of 7,7′-epoxylignan. The IC50 value of natural (−)-verrucosin was 6.6 μM.
title: 01_1297
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 1 of Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia
Creators: name: Hanren Dai
name: Zhiqiang Wu
name: Hejin Jia
name: Tong, Chuan
name: Yelei Guo
name: Dongdong Ti
name: Han, Xiao
name: Liu, Yang
name: Wenying Zhang
name: Chunmeng Wang
name: Yajing Zhang
name: Meixia Chen
name: Qingming Yang
name: Wang, Yao
name: Weidong Han
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Additional file 1.
Rutgers-Eagleton Poll #189: New Jersey late-October 2013
Creators: name: Eagleton Institute Of Politics, Rutgers University
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Registered to vote (1); favorability of public figures (7); President Barack Obama job performance (1); Governor Christopher Christie job performance (8); New Jersey right/wrong direction (1); most important problem (1); last time you voted (1); how closely are you following news about governor's election (1); debates between Christie and Senator Barbara Buono (1); voter likelihood (1); Buono vs. Christie (5); contacted by campaign (2); news sources for gubernatorial campaign (6); campaign ads (2); reasons why Buono is behind Christie in the polls (2); Democrats or Republicans for the New Jersey Assembly (2); Democrats or Republicans for the New Jersey State Senate (2); Democratic control of New Jersey legislature (1); minimum wage amendment to state constitution (1); Christie run for president (5); Christie conversational style (1); Superstorm Sandy recovery (4); voted in special election for Senate (2); union membership (2).
Snæfellsjökull volcano-centred ice cap landsystem, West Iceland
Creators: name: Evans, David J.A.
name: Ewertowski, Marek
name: Orton, Chris
name: Harris, Charlotte
name: Guðmundsson, Snævarr
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer

description: A 1:10,526 scale map of Snæfellsjökull and its forelands is presented as the first landsystem exemplar of volcano-centred ice caps, for application to understanding glacierized volcanic terrains globally. Mapping of surface materials and landforms was undertaken using orthorectified aerial photographs taken in 2002 and results of ground truth fieldwork in 2010. Nine natural surficial geology units were identified in addition to bedrock, glacier ice and made ground associated with pumice mining. The spatial distribution of landforms and sediments throughout the forelands comprises extensive areas of ice-cored moraine, developed at the limit of the Little Ice Age readvance and located distal to extensive areas of fluted till and glacially abraded bedrock with occasional eskers. This is a widely recognized landsystem signature typical of former polythermal snout conditions at the Little Ice Age maximum. Proglacially, thrust pumice sheets also occur on the east flanks of the volcano where pre-existing deformable materials were susceptible to thrust block development.
MILLIY  KOLORIT VA REALIYALARNI O'ZBEK TILIDAN INGILIZ VA RUS TILLARIGA TARJIMA QILISHDAGI SEMANTIKASINING MATNLARDAGI IFODASI
Creators: name: Noraliyev O'ralbek Baxtiyor o'g'li
Publisher: name: Zenodo
Year: 2024

description: Realiyalarning transliteratsiya usulida tarjima qilinishi haqida so’z borar ekan, o’zbek millati va o’zbek xalqiga xos, o’zbek madaniy hayotini ifodalovchi realiyalarning rus va ingiliz tillariga tarjima qilingan matnlardagi ifodasi borasida to’xtalamiz. Realiyalarni tarjima qilish usullari, xususan, transliteratsiya haqida so„z yuritilgan. Realiyalarning atamalardan farqi ochib berilgan. Realiya birliklar semantikasining xalq dunyoqarashi, turmush tarzi, madaniy munosabatlar bilan aloqadorligi ta"kidlangan.

Kalit so’zlar. Realiya, transliteratsiya, millat va elatlarga xos boʻlgan moddiy madaniyat obyektlari, tarixiy faktlar, atama, badiiy birlik, leksema, semantika
Rutgers-Eagleton Poll #188: New Jersey early-October 2013
Creators: name: Eagleton Institute Of Politics, Rutgers University
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Registered to vote (1); favorability of public figures (6); 0-100 scale of feeling to public figures (4); President Barack Obama job performance (1); Governor Christopher Christie job performance (8); New Jersey right/wrong direction (1); most important problem (1); government shutdown (1); last time you voted (1); October special election for New Jersey senator (4); New Jersey gubernatorial election (3); Senator Cory Booker vs. Steven Lonegan (3); Cory Booker issues (2); Steve Lonogan issues (2); Booker as Newark mayor (1); map of Newark on Twitter (1); Senator Barbara Buono vs. Christie (14); Christie ideology (3); Buono ideology (3); Christie characteristics (13); how does reading or hearing about Christie make you feel (1); same-sex marriage (8); relationships with gay or lesbian people (3); race-relations (3); union membership (2); household phones (2).
title: Analysing the effect of Hungary's dependence on Russian energy on the exchange rate volatility of the Hungarian Forint using ARCH-analysis
Creators: name: Weinwurm, Fanni Gabriella
Year: 2024

description: Die russische Energieabhängigkeit in der mitteleuropäischen Region ist ein interessantes Analysefeld, insbesondere seit dem Beginn des russisch-ukrainischen Konflikts im Jahr 2022, der die gesamte Europäische Union - insbesondere die V4-Länder - einer Energieversorgungsunsicherheit ausgesetzt hat. Während die Wechselkursvolatilität der Währungen der mittel- und osteuropäischen Länder und ihre Beziehung zum Erdöl bereits ausgiebig erforscht wurde, hat bisher keine Studie versucht, die Auswirkungen der russischen Energieabhängigkeit auf die nationalen Währungen zu untersuchen. Ziel der vorliegenden Arbeit ist eine detaillierte Untersuchung dieser Beziehung für den ungarischen Forint, den polnischen Zloty und die tschechische Krone, wobei das britische Pfund als westeuropäische Referenzwährung dient. Unter Verwendung des DCC-GARCH(1,1)-Rahmens und des Diebold-Yilmaz-Volatilitäts-Spillover-Index in Anlehnung an die Arbeit von Kočenda und Moravcová (Kočenda - Moravcová, 2019) werden in dieser Arbeit die Ko-Bewegungen und direktionalen Spillovers zwischen den Währungen, den Henry Hub-Gaspreisen, den Brent-Rohölpreisen und dem russischen Rubel für den Zeitraum 2004-2022 untersucht. Die Ergebnisse deuten auf eine schwache Abhängigkeit der mitteleuropäischen Wechselkurse von den globalen Rohstoffpreisen und dem Wechselkurs des Rubels hin. Die These unterstreicht auch, dass der Forint und der Zloty im Vergleich zur tschechischen Krone und zum britischen Pfund stärker von russlandbezogenen Rohstoffnachrichten abhängen.
description: Russian energy dependence in the Central European region is an interesting field of analysis, especially since the start of the Russian-Ukrainian conflict in 2022, which has exposed the entire European Union – especially V4 countries – to energy supply uncertainty. While there has been extensive research investigating exchange rate volatility of CE currencies and their relationship with oil, no study has attempted to investigate the effect of Russian energy dependence on national currencies. The aim of the current thesis is to provide a detailed inspection of this relationship for, the Hungarian forint, the Polish zloty, and the Czech koruna, with the British pound as a Western European benchmark currency. Using the DCC-GARCH(1,1) framework and the Diebold-Yilmaz volatility spillover index following the work of Kočenda and Moravcová (Kočenda – Moravcová, 2019), the thesis investigates the co-movements and directional spillovers between the currencies, Henry Hub gas prices, Brent crude oil prices, and the Russian rouble for the time period 2004-2022. Results indicate weak exposure of Central European exchange rates to global commodity prices and the rouble’s exchange rate. The thesis also highlights the increased exposure of the forint and the zloty to Russia-related commodity news compared to the Czech koruna and the British pound.
National Honors: Royal Honors of New Zealand
Creators: name: Murawski, Mark
name: Boyd, Christian
Publisher: name: figshare
Year: 2022
Subjects: subject: 210311 New Zealand History
subject: FOS: History and archaeology

description: This is an article in a series documenting the various orders of chivalry and national hoors from around the world. This article provides a basic overview of the Royal Honors of New Zealand as well as the heraldic privileges of the recipients.
La(OTf)3-catalyzed, three-component synthesis of spiro[Indolo-3,10′-indeno[1,2-b]quinolin]-2,4,11′-triones in PEG-400 under conventional heating and ultrasonic irradiation
Creators: name: Kumari, Sudesh
name: M. Rajeswari
name: J. M. Khurana
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: Computational Biology

description: An efficient La(OTf)3-catalyzed three-component reaction has been developed for the synthesis of highly substituted spiro[indolo-3,10′-indeno[1,2-b]quinolin]-2,4,11′-triones in polyethylene glycol (PEG-400) under conventional heating and ultrasonic irradiation. The most exciting feature of this methodology is its mechanism involving the unusual ring opening of an isatin moiety followed by recyclization. All the reactions resulted in good yield of products. The important features of this reaction are use of green solvent, good yields, less reaction times, and recyclability of the catalyst.
Supplementary Material 2 - Paper: Investigating the genomic background of calving-related traits in Canadian Jersey cattle
Creators: name: Brito, Luiz
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 300305
subject: Animal reproduction and breeding

description: Supplementary Material 2 - Paper: Investigating the genomic background of calving-related traits in Canadian Jersey cattle
Synthesis of N1 and N2 coumarin substituted 1,2,3-triazole isomers via click chemistry approach
Creators: name: Devadas Shamala
name: Kalegowda Shivashankar
name: , Chandra
name: Madegowda Mahendra
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology
subject: Computational Biology

description: The synthesis of N1 and N2 coumarin substituted 1,2,3-triazole isomers from terminal alkynes, sodium azide, and 4-bromomethylcoumarins in the presence of triethylamine as a base and CuI as a catalyst in good yield are reported. The molecular structure of compounds 3g and 5d are established by single-crystal analysis.
Multicomponent reaction of benzyl halides: Synthesis of [1,2,4]triazolo/benzimidazolo quinazolinones
Creators: name: Mallappa Beerappa
name: Kalegowda Shivashankar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: We demonstrated a simple, highly efficient, one-pot method to construct triazolo/benzimidazolo quinazolinones through a cascade of oxidation, Knoevenagel condensation, and Michael addition followed by cyclization and dehydration. This protocol tolerates easily available benzyl halides, 2-amino benzimidazole/3-amino-1,2,4-triazole, and α-hydroxy C-H acids as starting materials using trimethyl amine N-oxide in ethanol. To the best of our knowledge, this is the first example of synthesis of triazolo/benzimidazolo quinazolinones directly from benzyl halides in one pot. Simple procedure, environmental friendliness, mild reaction conditions, and good yields are the attractive features of this method.
La(OTf)3 Catalysed Three-Component Synthesis of Spiro[indolo-3,10′-indeno[1,2-b]quinolin]-2,4,11′-triones in PEG-400 Under Conventional Heating and Ultrasonic Irradiation
Creators: name: Kumari, Sudesh
name: M. Rajeswari
name: J. M. Khurana
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: Computational Biology

description: An efficient La(OTf)3 catalyzed three-component reaction has been developed for the synthesis of highly substituted spiro[indolo-3,10′-indeno[1,2-b]quinolin]-2,4,11′-triones in PEG-400 under conventional heating and ultrasonic irradiation. The most exciting feature of this methodology is its mechanism involving the unusual ring opening of an isatin moiety followed by recyclisation. All the reactions resulted in high yield of products. The important features of this reaction are use of green solvent, high yields, less reaction times and recyclability of the catalyst.
title: Für diese Minuten war sie die Norm
Creators: name: Kirner, Alexander
Year: 2024

description: In der vorliegenden Arbeit wird der Roman Biskaya von SchwarzRund (2020) sowie der vierte Handlungsstrang aus Adas Raum von Sharon Dodua Otoo (2021) mittels Interdependenzanalyse auf postkoloniale, interkategoriale Verbindungen in den Darstellungen von Anti-Schwarzem Rassismus sowie von Schwarzem Empowerment untersucht. Das Ergebnis der Analyse zeigt, dass die Positionierungen als Schwarz sowie als weiß aufgrund postkolonialer Dynamiken in den Erzählwelten nicht losgelöst von weiteren sozialen Kategorisierungen gesehen werden können, mit denen sie als interdependent miteinander verbunden aufscheinen. Neben Aspekten von Gender und Begehren beeinflussen ebenso Dimensionen von Sprache, Kleidung, Geschlechtsausdruck und Essen die Positionierungen der jeweiligen Figuren in den Erzählwelten. Für Schwarzes Empowerment erscheinen – neben den zuvor genannten Dimensionen – das Schaffen und Rezipieren von Kunst sowie Dynamiken von Wahlfamilie, Community und dadurch entstehender Safer Spaces als relevant. Das Konzept der Wahlfamilie wird dabei in Geschwisterschaft und in Elternschaft unterteilt. Es wurde außerdem gezeigt, dass die Darstellungen in den Romanen Parallelen zur realen Welt aufweisen. Dies ermöglicht die Zuordnung der Narrative zu Schwarzen und PoC-Wissensarchiven.
Multicomponet Reaction of Benzyl Halides: Synthesis of [1,2,4]Triazolo/Benzimidazolo Quinazolinones
Creators: name: Mallappa Beerappa
name: Kalegowda Shivashankar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: We demonstrated a simple and highly efficient new one-pot method to construct triazolo/benzimidazolo quinazolinones through a cascade of oxidation, Knoevenagel condensation and Michael addition followed by cyclization and dehydration. This protocol tolerates easily available benzyl halides, 2-amino benzimidazole/3-amino-1,2,4-triazole and α-hydroxy C-H acids as starting materials using trimethyl amine N-oxide in ethanol. To the best of our knowledge, this is the first example of synthesis of triazolo/benzimidazolo quinazolinones directly from benzyl halides in one pot. Simple procedure, environmental friendly, mild reaction condition and high yield are the attractive features of this method.
Synthesis of N1 and N2 Coumarin Substituted 1,2,3-Triazole Isomers via Click Chemistry Approach
Creators: name: D. Shamala
name: K. Shivashankar
name: , Chandra
name: M. Mahendra
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology
subject: Computational Biology

description: The synthesis of N1 and N2 coumarin substituted 1,2,3-triazole isomers from terminal alkynes, sodium azide and 4-bromomethylcoumarins in the presence of triethylamine as a base and CuI as a catalyst in good yield are reported. The molecular structure of the compounds (3g) and (5d) are established by single crystal analysis.
التردد وحده ليس يكفي!
Creators: name: Madi, Amr
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390307
subject: Teacher education and professional development of educators
classificationCode: 470401
subject: Applied linguistics and educational linguistics

description: تحاول هذه الورقة الإجابة عن: ما المعايير الواجب توافرها في بناء معجم شيوع لمتعلمي العربية لغةً ثانية؟ وتدَّعي الورقة أن التردد/التكرار وحده ليس معيارًا كافيًا لبناء معجم للشيوع؛ إذ ينبغي أن تؤسَس الوظيفية معيارًا بجانبه. وتُعِد الشيوع مصطلحًا أعم ينبغي أن يشمل تحته التردد أو التكرار، جنبًا إلى جنب مع الوظيفية تقدم الورقة، أولًا، لدور المفردات في عملية التعلم، ثم تعرّج، ثانيًا، على مفهوم الكفاءة والوظيفية. وبعد ذلك، ثالثًا، تعرض لأهم الدراسات السابقة في المجال محللة إياها، وكاشفة عن العوار الذي يظهر فيها بغياب الوظيفية، وتقدم الطرح الذي تراه نموذجيًّا في بناء معجم للشيوع في مجال العربية لغةً ثانيةً. وكل ما سبق يقع بين مقدمة وخاتمة، ثم تأتي قائمة المصادر والمراجع.
A Bayesian Markov-Switching Correlation Model for Contagion Analysis on Exchange Rate Markets
Creators: name: Casarin, Roberto
name: Sartore, Domenico
name: Tronzano, Marco
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: This article develops a new Markov-switching vector autoregressive (VAR) model with stochastic correlation for contagion analysis on financial markets. The correlation and the log-volatility dynamics are driven by two independent Markov chains, thus allowing for different effects such as volatility spill-overs and correlation shifts with various degrees of intensity. We outline a suitable Bayesian inference procedure based on Markov chain Monte Carlo algorithms. We then apply the model to some major and Asian-Pacific cross rates against the U.S. dollar and find strong evidence supporting the existence of contagion effects and correlation drops during crises, closely in line with the stylized facts outlined in the contagion literature. A comparison of this model with its closest competitors, such as a time-varying parameter VAR, reveals that our model has a better predictive ability. Supplementary materials for this article are available online
Structural diversity and similar bioactivity in synthetic bicyclononanes
Creators: name: Luna, Liliana E.
name: Forastieri, Pamela S.
name: Marchiaro, Patricia
name: Limansky, Adriana
name: Cravero, Raquel M.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Simple syntheses of diverse bicyclo[3.3.1]nonanes and related compounds as the minimal substructure of bioactive natural products via Michael, aldol, and alkylation reactions from diketones are described herein. The structures of the synthesized compounds were determined by infrared spectroscopy, NMR (1H and 13C), and electrospray ionization–high-resolution mass spectrometry. We also show the in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria. The qualitative analysis has revealed that the new synthesized compounds 5, 6, 9, and 11 present antibacterial properties.
Factors Associated with Disability and Mortality among Necrotizing Fasciitis Patients in Thailand, 2018
Creators: name: Hirunwut Praekunatham
Publisher: name: Division of Epidemiology
Year: 2020
Subjects: necrotizing fasciitis, NF, disability, mortality, risk factor

description: Outbreak, Surveillance, Investigation & Response Journal, 13, 2, 9-16
Factors Associated with Knowledge and Practice of Healthcare Workers in Cervical Cancer Screening in Ratchaburi Province, Thailand
Creators: name: Chalo Sansilapin
Publisher: name: Division of Epidemiology
Year: 2020
Subjects: cervical cancer, cancer screening, Papanicolau smear

description: Outbreak, Surveillance, Investigation & Response Journal, 13, 1, 1-8
Structural Diversity and Similar Bioactivity in Synthetic Bicyclo Nonanes
Creators: name: Luna, Liliana E.
name: Forastieri, Pamela S.
name: Marchiaro, Patricia
name: Limansky, Adriana
name: Cravero, Raquel M.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Simple syntheses of diverse bicyclo[3.3.1]nonanes and related compounds as the minimal substructure of bioactive natural products via Michael, aldol, and alkylation reactions from diketones, are described herein. The structures of the synthesized compounds were determined by IR, NMR (1H and 13C) and ESI-HRMS. We also show the in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria. The qualitative analysis has revealed that the new synthesized compounds 5, 6, 9 and 11 present antibacterial properties.
Predicting Blood Lead Levels among Children Living in Households Making Fishing Nets with Lead Weights in Phuket and Phang Nga Provinces
Creators: name: Thanawadee Chantian
Publisher: name: Division of Epidemiology
Year: 2020
Subjects: child, lead, Thailand

description: Outbreak, Surveillance, Investigation & Response Journal, 13, 3, 17-25
A Comparative Study of Success Factors and Challenges for Reward-Based Crowdfunding Campaigns In The UK and China (Hou, Y. and Phillips, R.A. (2024) Journal of Asia Entrepreneurship and Sustainability Vol. 20 (3) pp.77-138.
Creators: name: Phillips, Robert
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 350202
subject: Finance
classificationCode: 350208
subject: Investment and risk management

description: Crowdfunding represents an alternative funding mechanism for entrepreneurs to obtain funds from the public and raise awareness of a new project. The reward-based model allows founders to supply rewards which are digital or physical rather than financial. This paper analyses success factors and barriers for reward-based crowdfunding campaigns focusing on the similarities and differences between campaigns in the UK and China. Eight successful project founders were interviewed – four from each country.
title: Psychophysiological Measures and Performance Effects in an Adaptive Sustained Attention Task
Creators: name: Hadley, Gerald Alan
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2001

description: This experiment examined the effect of a biocybernetic system that had been successfully used to control an adaptive automation compensatory tracking task (Freeman, Mikulka, Prinzel, & Scerbo, 1999; Pope, Bogart, & Bartolome, 1995). The present study applied this adaptive automation system to a vigilance task. Recordings of EEG activity were used to derive an index of task engagement, beta/(alpha+ theta). A training session was used to establish a baseline level of this index. Index levels above baseline reflected an increase in arousal, while levels below baseline indicated decreased arousal. Three groups (production, reception, and control) performed the task which presented one target per minute coupled with non-target event rates of 6, 20, and 60 per minute. The production group used a negative feedback methodology in which EEG index values reflecting increased arousal produced a lower non-event rate. A yoked (reception) group was given the same pattern of event rate shills as the production group. The control group was simply required to perform the task with the event rate changing at random. Production group participants showed an attenuated decrement in accuracy scores over time. These initial results suggest that the biocybemetic system may provide a method of reducing the traditional vigilance decrement.
Biomimetic epoxidation in aqueous media catalyzed by cyclic dipeptides
Creators: name: Bérubé, Christopher
name: Voyer, Normand
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: We have developed a practical epoxidation of electron-deficient enones in aqueous media using cyclic dipeptides as bioinspired green catalyst. Optimizing the reaction conditions in a triphasic system led to efficient conditions providing epoxides with good enantioselectivities. Depending on the catalyst substituent chirality, both enantiomers are obtained. The cyclic rigidity impacts significantly the enantioselectivity.
PEG-400 as an efficient and recyclable reaction medium for the synthesis of 2-aryl-2-methyl-4,5-diphenyl-2,3- dihydro-2H-imidazoles
Creators: name: Nageshwar Rao Penumati
name: Lingayya Rajaka
name: Nagaiah Kommu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: A productive natural method has been produced for the synthesis of 2-aryl-2-methyl-4,5-diphenyl-2,3-dihydro-2H-imidazoles in great yields under catalyst free-conditions utilizing polyethylene glycol (PEG-400) as a green reaction medium. The highlights of this new method are shorter reaction times, good yields, room temperature, and use of nontoxic, inexpensive, and recyclable PEG-400.
Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications
Creators: name: Cording, Amy
name: Gormally, Michael
name: Bond, Peter J.
name: Carrington, Mark
name: Balasubramanian, Shankar
name: Miska, Eric A.
name: Thomas, Beth
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Non-coding RNAs are crucial regulators for a vast array of cellular processes and have been implicated in human disease. These biological processes represent a hitherto untapped resource in our fight against disease. In this work we identify small molecule inhibitors of a non-coding RNA uridylylation pathway. The TUTase family of enzymes is important for modulating non-coding RNA pathways in both human cancer and pathogen systems. We demonstrate that this new class of drug target can be accessed with traditional drug discovery techniques. Using the Trypanosoma brucei TUTase, RET1, we identify TUTase inhibitors and lay the groundwork for the use of this new target class as a therapeutic opportunity for the under-served disease area of African Trypanosomiasis. In a broader sense this work demonstrates the therapeutic potential for targeting RNA post-transcriptional modifications with small molecules in human disease.
إستراتيجيات تدريس مهارة الكتابة في تعلم العربية كلغة ثانية.pdf
Creators: name: Madi, Amr
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 470401
subject: Applied linguistics and educational linguistics

description: تحاول هذه الورقة الإجابة عن: ما الإستراتيجيات التواصلية التي من خلالها يتم رفع الكفاءة في مهارة الكتابة؟ والكتابة في تعلم اللغة الثانية لها أنواع كثيرة، تبدأ بتعلم الحروف كتابةً، ثم تعلم كتابة المفردات والتوسع إلى الجمل ثم الفِقَر فالخطابات المستفيضة والنصوص. وهناك الكتابات اليومية التي يقوم بها المتعلمون في واجباتهم من دراسة للمفردات الجديدة أو القواعد الجديدة، كملء فراغات مثلا، أو الاستماع إلى جمل وكتابتها، أو أخذ ملاحظ لغوية على نص قراءة أو استماع، أو غيرها من الكتابات اليومية الروتينية. وهناك الكتابات الطويلة التي تأتي بعد الانتهاء من وحدة أو درس، أو كل أسبوع أو أسبوعين حسب خطة الأساتذة، وهي ما أسميها بالكتابات الطويلة، وهذه هي الكتابة التي نعينها في سطورنا هذه، وهي محل بحثنا.ويبدأ البحث بمقدمة نبين فيها قيمة الكتابة وأثرها في عملية التعلم، ثم نعرّج سريعا في على معايير الكفاءة اللغوية، ومبادئ التعلم التي تسهم في رفع الكفاءة اللغوية للمتعلمين. ثم نتناول إجراءات تعلّم الكتابة التواصلية بداية من تصميم أنشتطها إلى عملية التصحيح وما بعد الكتابة. أما الجزء الأخير من البحث فقد خصصناه للتعرف على دور الأساتذة في مهارة الكتابة وذيّلنا ذلك ببعض التحديات الخاصة التي قد تواجه بعض الأساتذة في عملية تعلم الكتابة. ثم جاءت الخاتمة لتنص على خلاصة ما قدمنا، وتمدّ يدا للبحوث القادمة. وفي النهاية وضعتُ ثبت المصادر والمراجع.