cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
"English Professor Uses AI to Teach Shakespeare and Critical Theory." GW Today, April 12, 2023
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Artificial intelligence--Social aspects
subject: Digital humanities
subject: Teaching
subject: Shakespeare, William, 1564-1616
subject: Social justice
subject: Critical theory

description: When ChatGPT was launched, Alexa Alice Joubin realized it was here to stay. She views it as her responsibility to teach students how to use it responsibly, not as a shortcut. “This technology is going to be with us, and students need employable skills in terms of curation, editorial repackaging and prompt engineering,” Joubin said. “They need to be able to formulate good queries—the quality of their queries is really important in this search-driven culture.” The skill to search for information and the ability to evaluate it are important assets in the job market and in life in general, Joubin said. “In our inquiry-driven culture, we need to know how to retrieve information through queries,” Joubin said. “Further, democratic society needs good question-askers as much as good problem-solvers. Asking key questions helps to advance scholarly fields, and students develop editorial, curatorial and critical questioning skills that are employable skills and the foundation of civil society in an era of ChatGPT.”
Mobility, Survival, and the Female Body in Laila Lalami᾿s Hope and Other Dangerous Pursuits
Creators: name: Abbady, Amel
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: Emigration and immigration
subject: Muslim women

description: Abstract of my book chapter, published in Memory, Voice, and Identity Muslim Women’s Writing from across the Middle East Edited By Feroza Jussawalla, Doaa Omran
Mobility, Survival, and the Female Body in Laila Lalami᾿s Hope and Other Dangerous Pursuits
Creators: name: Abbady, Amel
Publisher: name: Routledge
Year: 2021
Subjects: subject: Emigration and immigration
subject: Muslim women

description: Abstract of my book chapter, published in Memory, Voice, and Identity
Muslim Women's Writing from across the Middle East
Edited By Feroza Jussawalla, Doaa Omran
In Vino Veritas: Wine, Sex, and Gender Relations in Late Medieval and Early Modern Spanish Literature
Creators: name: Kang, Minji
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Literature in Spanish and Portuguese

description: Alcohol has been present in almost every society throughout history, and so has a double standard around alcohol usage: women are stigmatized far more than men for excessive drinking. In this dissertation, I explore the intimate association between wine consumption and gender relations in Spanish late medieval and early modern literature. In late medieval and early modern European society, distinctions of gender, age, class, religion, and occupation were reflected in what one chose to eat and drink. Wine was undoubtedly the most popular and highly regarded beverage, especially in the Iberian Peninsula and the rest of southern Europe. Wine has always been deeply integrated into the Spaniards’ lives, not only as a daily beverage but also as a marker of individual and group identities. While references to wine have flowed through Spanish literature, thorough examinations of women’s drinking have surprisingly been left unexplored. This study fills that gap, analyzing representations of female drinking in Spanish literature, specifically the ambivalent approach to wine as it relates to the construction of gender identities. This study analyzes the representation of female drinking throughout the Spanish literary canon, especially focusing on the Libro de buen amor (ca. 1343), the Arcipreste de Talavera (also called as Corbacho, ca. 1438), and the Tragicomedia de Calisto y Melibea (also known as Celestina, 1502) with the purpose of demonstrating how wine consumption constitutes, reflects, and questions normative gender roles. In medieval and early modern Europe, gender identities were either masculine or feminine, attached to rigid, stereotypical gender roles for men and women. Drunken women, therefore, presented a threat that needed to be contained. During the Middle Ages, while drunken women were represented as personifying gluttony and violating both moral and gender norms in didactic, moralizing treatises, there were literary fictions that depicted female drunkards who openly enjoyed wine, praised its virtues, and socialized by drinking with other women. The gender ideology of Spanish patriarchy created masculine anxiety around unfeminine women, like female drunkards, who were unsuited to a life of purity and chastity. I argue that this anxiety, evident in the extreme condemnation of drunken women, paradoxically reveals the contradictions underlying the patriarchal agenda. I also interpret female drinking practices as performative acts of resistance against normative gender roles. Drawing on the notion that gender is a performative act, alcohol drinking by women can be understood as a subversive act that transgresses and reconfigures social norms around gendered identities in late medieval and early modern Spain.
sj-pdf-1-mpp-10.1177_23814683211033249 – Supplemental material for Using Mixed Methods With Multiple Stakeholders to Inform Development of a Breast Cancer Screening Decision Aid for Women With Limited Health Literacy
Creators: name: Gunn, Christine M.
name: Maschke, Ariel
name: Paasche-Orlow, Michael K.
name: Housten, Ashley J.
name: Kressin, Nancy R.
name: Schonberg, Mara A.
name: Battaglia, Tracy A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-mpp-10.1177_23814683211033249 for Using Mixed Methods With Multiple Stakeholders to Inform Development of a Breast Cancer Screening Decision Aid for Women With Limited Health Literacy by Christine M. Gunn, Ariel Maschke, Michael K. Paasche-Orlow, Ashley J. Housten, Nancy R. Kressin, Mara A. Schonberg and Tracy A. Battaglia in MDM Policy & Practice
Foraging Ecology and Stress in Sea Turtles
Creators: name: Clyde-Brockway, Chelsea E
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Animal physiological ecology
Animal physiology - systems
Marine and estuarine ecology (incl. marine ichthyology)

description: As ectothermic marine megafauna, sea turtle physiology and ecology are tightly intertwined with temperature, seasonality, and oceanography. Identifying how turtles respond when exposed to cold water, how they adapt to cold environments when they need to explore cold environments in order to forage, and what foraging resources are exploited by sea turtles are all components central to their conservation. Cold-stunning is a well-documented phenomenon that occurs when water induced decreases in sea turtle body temperature cause turtles to become immobilized and wash ashore. While most cold-stunned turtles are rescued and rehabilitated, we do not know whether cold-stunning is an acute transient occurrence, or a symptom of a bigger environmental problem. Further, while in some environments avoiding cold water is preferential, in other habitats, sea turtles need to inhabit cold environments in order to forage. Along the Eastern Pacific Rim, discrete upwelling locations are characterized by high primary productivity and unusually cold water. In these environments, avoidance is not possible and sea turtles require physiological adaptions to mitigate body temperature decreases in cold water. Little is known about how turtles handle upwelling environments, despite the fact that sea turtles remain in these habitats regardless of water temperature fluctuations. Because upwelling habitats provide increased nutrient presence, and sea turtles are opportunistic foragers, quantification of diet composition will further our understanding of why sea turtles remain in cold water environments year-round. Diet composition in multiple populations of cohabitating sea turtles revealed partitioning that results in reduced inter-specific competition. Further, flexibility in diets provides a wide range of ecosystem services central to habitat resiliency. Therefore, conservation of endangered sea turtles requires complete ecosystem conservation, and complete understanding of the interconnectivity of sea turtles and their environments is crucial.
“The past goes to sleep, and wakes up inside you”: Identity Crisis in Hassan Blasimʼs “The Nightmares of Carlos Fuentes”
Creators: name: Abbady, Amel
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Political refugees
subject: Iraq War (2003-2011)
subject: Assimilation (Sociology)
subject: Abjection in literature

description: This article examines “The Nightmares of Carlos Fuentes,” the last of the fourteen stories that comprise Iraqi writer Hassan Blasimʼs collection The Corpse Exhibition. In “The Nightmares” Blasim is not concerned at all about depicting the reception of refugees in Europe. As evident in the title itself, what is central to the story is the psychological impacts of war on the individual. Drawing on Julia Kristevaʼs psychologically-informed theory of the abject, this article attempts to show how the central character in Blasimʼs short story situates his ethnic origin as an abject object that he should avoid by all means to be able to bury the traumatizing memories of the war. The article argues that, by situating the crisis of identity in the context of the protagonistʼs nightmares, Hassan Blasim manages to articulate the anxieties of exile and the complexity of identity construction particularly for traumatized individuals. Despite his constant denial and avoidance, the central character in the story, Carlos Fuentes, fails to neither construct a hybrid identity nor bury his former self.
Increasing Occurrence of Multidrug-Resistance in Acinetobacter baumannii Isolates From Four German University Hospitals, 2002–2006
Creators: name: Wadl, Maria
name: Heckenbach, Kirsten
name: Noll, Ines
name: Ziesing, S.
name: Pfister, W.
name: Beer, J.
name: Schubert, S.
name: Eckmanns, Tim
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2010
Subjects: subject: Bacterial
subject: Humans
subject: Female
subject: Germany/epidemiology
subject: Male
subject: Middle Aged
subject: Aged
subject: Retrospective Studies
subject: Drug Resistance
subject: Microbial Sensitivity Tests
subject: Aged 80 and over
subject: Multiple
subject: Hospitals University
subject: Acinetobacter Infections/epidemiology
subject: Acinetobacter Infections/microbiology
subject: Acinetobacter baumannii/drug effects
subject: Acinetobacter baumannii/isolation & purification
subject: 610 Medizin

description: Background: Acinetobacter baumannii can cause severe infections, mainly in critically ill inpatients. Treatment is complicated by multidrug-resistance (MDR). In Germany, to date, little is known on the extent of MDR in A. baumannii isolated from inpatients in German hospitals and potential factors influencing the emergence of MDR. Materials and Methods: We retrospectively analysed the data of A. baumannii isolates from the inpatients of four German university hospitals, tested for antimicrobial resistance with the broth dilution method between 2002 and 2006. We defined MDR as resistance to three or more classes of recommended drugs. After calculating the proportions of MDR in A. baumannii isolates, we investigated the association between MDR in A. baumannii and year of pathogen isolation, hospital, ward type, specimen and demographics. We performed descriptive analysis and multivariable logistic regression. Additionally, proportions of in vitro drug effectiveness against multidrug-resistant and non-multidrugresistant A. baumannii isolates were determined. Results: MDR was found in 66 of 1,190 (5.6%) A. baumannii isolates and increased from 2.1% in 2002 to 7.9% in 2006. The highest proportions of MDR were found in hospital A (8.9%), in intensive care units (7.3%), in isolates from blood (7.6%) and in male patients aged 60 years or older (6.6%). In multivariable analysis, the chance of MDR in A. baumannii isolates increased with the successive years of pathogen isolation (odds ratio [OR] 1.3, 95% confidence interval [CI] 1.1–1.5) and there was a higher risk of MDR in A. baumannii in intensive care units (OR 1.8, 95% CI 1.1–2.9). The lowest in vitro antibiotic resistance was found in meropenem, imipenem and ampicillin/sulbactam, with 33, 37 and 39% for multidrugresistant and 0.4, 1 and 3% in non-multidrug-resistant A. baumannii isolates, respectively. Conclusions: The increase of MDR in A. baumannii isolates from 2002 to 2006 in four hospitals suggests that clinicians in Germany may expect a rising proportion of MDR in A. baumannii isolates among inpatients. The antimicrobial susceptibility testing of A. baumannii isolates against recommended drugs, combined with in-house antimicrobial resistance surveillance, is needed to ensure appropriate treatment.
Integrated MicroRNA-mRNA-Analysis of Human Monocyte Derived Macrophages upon Mycobacterium avium subsp. hominissuis Infection
Creators: name: Sharbati, Jutta
name: Lewin, Astrid
name: Kutz-Lohroff, Barbara
name: Kamal, Elisabeth
name: Einspanier, Ralf
name: Sharbati, Soroush
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2011
Subjects: subject: Humans
subject: Oligonucleotide Array Sequence Analysis
subject: Macrophages/microbiology
subject: Cells Cultured
subject: 3' Untranslated Regions/genetics
subject: Macrophages/metabolism
subject: MicroRNAs/genetics
subject: Mycobacterium avium/physiology
subject: RNA Messenger/genetics
subject: Tuberculosis/genetics
subject: Tuberculosis/microbiology
subject: 610 Medizin

description: Background: Many efforts have been made to understand basal mechanisms of mycobacterial infections. Macrophages are the first line of host immune defence to encounter and eradicate mycobacteria. Pathogenic species have evolved different mechanisms to evade host response, e.g. by influencing macrophage apoptotic pathways. However, the underlying molecular regulation is not fully understood. A new layer of eukaryotic regulation of gene expression is constituted by microRNAs. Therefore, we present a comprehensive study for identification of these key regulators and their targets in the context of host macrophage response to mycobacterial infections. Methodology/Principal Findings: We performed microRNA as well as mRNA expression analysis of human monocyte derived macrophages infected with several Mycobacterium avium hominissuis strains by means of microarrays as well as quantitative reverse transcription PCR (qRT-PCR). The data revealed the ability of all strains to inhibit apoptosis by transcriptional regulation of BCL2 family members. Accordingly, at 48 h after infection macrophages infected with all M. avium strains showed significantly decreased caspase 3 and 7 activities compared to the controls. Expression of let-7e, miR- 29a and miR-886-5p were increased in response to mycobacterial infection at 48 h. The integrated analysis of microRNA and mRNA expression as well as target prediction pointed out regulative networks identifying caspase 3 and 7 as potential targets of let-7e and miR-29a, respectively. Consecutive reporter assays verified the regulation of caspase 3 and 7 by these microRNAs. Conclusions/Significance: We show for the first time that mycobacterial infection of human macrophages causes a specific microRNA response. We furthermore outlined a regulatory network of potential interactions between microRNAs and mRNAs. This study provides a theoretical concept for unveiling how distinct mycobacteria could manipulate host cell response. In addition, functional relevance was confirmed by uncovering the control of major caspases 3 and 7 by let-7e and miR-29a, respectively.
Investigating the Postcolonial Grotesque in Martin McDonaghʼs A Very Very Very Dark Matter
Creators: name: Abbady, Amel
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Grotesque in literature
subject: Postcolonialism
subject: McDonagh, Martin
subject: Andersen, H. C. (Hans Christian), 1805-1875

description: McDonagh is arguably one of the most celebrated yet most controversial of contemporary Anglo-Irish playwrights. His plays have received mixed reviews from critics and audiences alike, mostly for featuring graphic violence and obscene dialogues. Even though comedy is mostly seen as an inferior genre compared to tragedy, McDonagh, among many contemporary Anglo-Irish writers, makes use of the malleability of the grotesque to address myriads of serious issues. In his most recent play A Very Very Very Dark Matter (2018), McDonagh juxtaposes both comic and grotesque elements to create a black comedy that manages to represent the painful memories of colonial history. This comic mediation of pain and suffering is only one of the several aspects of the grotesque that are present in Dark Matter. Through a nuanced examination of the features and functions of the grotesque in Dark Matter, this articles aims to illustrate how, by means of the grotesque, McDonagh manages to address the seminal issues of colonialism and social justice. The article shows that by recurring to the shocking, the repugnant, and the fantastical, McDonagh manages to remind his audience of the ugliness of colonial realities. A careful examination of the play reveals that McDonagh employs the grotesque to undermine the power and arrogance of Europe and to remind the audience of the atrocities committed against Africa and other colonized nations in the name of white supremacy.
COVID-19 vaccine knowledge and acceptance among the Libyan population: A cross-sectional study
Creators: name: Shembesh, Rana H.
name: Beshr, Mohammed S.
name: ALTarhouni, Mariam M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: We aim to identify Libyans’ knowledge, attitudes, and acceptance regarding the COVID-19 vaccine. A cross-sectional survey was electronically distributed to the Libyan population aged 18 and older between May and September 2023. The questionnaire had three sections: socio-demographics, COVID-19 vaccination and infection, and knowledge and attitudes toward the COVID-19 vaccine. The chi-square test was used to assess the associations. A total of 1,043 respondents completed the questionnaire. Of these, 590 (56.6%) were vaccinated, and 453 (43.4%) were unvaccinated. Only age, educational level, employment status, history of COVID-19 infection, and source of information had a significant association with vaccination status; all shared a p-value <.05. However, Monthly income did not. Regarding knowledge, 63.7% agreed that vaccines in general are an effective way to prevent and control infectious diseases, and 76.6% agreed that they can prevent disease and mortality. However, regarding COVID-19 vaccine, 48.4% agreed that the benefits outweigh the risks. Regarding COVID-19 safety, 40.8% responded that COVID-19 vaccines are only slightly safe or not safe at all. COVID-19 vaccine acceptance was at 57.2%, and only age and source of information were significantly associated. Those who held favorable views were more likely to accept the vaccine, while those who had concerns about safety were more vaccine hesitant. There is a gap between the perception of the COVID-19 vaccine compared to other vaccines among Libyans. Our study revealed that 57.2% of Libyans accept the COVID-19 vaccine. However, only 34% of the Libyan population is vaccinated. A comprehensive health policy is needed.
sj-docx-1-sms-10.1177_20563051211033815 – Supplemental material for Tweeting About Climate: Which Politicians Speak Up and What Do They Speak Up About?
Creators: name: Yu, Chao
name: Margolin, Drew B.
name: Fownes, Jennifer R.
name: Eiseman, Danielle L.
name: Chatrchyan, Allison M.
name: Allred, Shorna B.
Publisher: name: SAGE Journals
Year: 2021
Subjects: Communication and Media Studies not elsewhere classified

description: Supplemental material, sj-docx-1-sms-10.1177_20563051211033815 for Tweeting About Climate: Which Politicians Speak Up and What Do They Speak Up About? by Chao Yu, Drew B. Margolin, Jennifer R. Fownes, Danielle L. Eiseman, Allison M. Chatrchyan and Shorna B. Allred in Social Media + Society
Genomic expression libraries for the identification of cross-reactive orthopoxvirus antigens.
Creators: name: Miller, Lilija
name: Richter, Marco
name: Hapke, Christoph
name: Stern, Daniel
name: Nitsche, Andreas
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2011
Subjects: subject: Humans
subject: Polymerase Chain Reaction
subject: Vaccinia virus/genetics
subject: Vaccinia virus/immunology
subject: Cowpox virus/genetics
subject: Cowpox virus/immunology
subject: Genome Viral/genetics
subject: Orthopoxvirus/genetics
subject: Orthopoxvirus/immunology
subject: Viral Vaccines/immunology
subject: 610 Medizin

description: Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young nonvaccinated persons have renewed interest in this zoonotic disease. Usually causing a self-limiting local infection, human cowpox can in fact be fatal for immunocompromised individuals. Conventional smallpox vaccination presumably protects an individual from infections with other Orthopoxviruses, including cowpox virus. However, available live vaccines are causing severe adverse reactions especially in individuals with impaired immunity. Because of a decrease in protective immunity against Orthopoxviruses and a coincident increase in the proportion of immunodeficient individuals in today’s population, safer vaccines need to be developed. Recombinant subunit vaccines containing cross-reactive antigens are promising candidates, which avoid the application of infectious virus. However, subunit vaccines should contain carefully selected antigens to confer a solid cross-protection against different Orthopoxvirus species. Little is known about the crossreactivity of antibodies elicited to cowpox virus proteins. Here, we first identified 21 immunogenic proteins of cowpox and vaccinia virus by serological screenings of genomic Orthopoxvirus expression libraries. Screenings were performed using sera from vaccinated humans and animals as well as clinical sera from patients and animals with a naturally acquired cowpox virus infection. We further analyzed the cross-reactivity of the identified immunogenic proteins. Out of 21 identified proteins 16 were found to be cross-reactive between cowpox and vaccinia virus. The presented findings provide important indications for the design of new-generation recombinant subunit vaccines.
Supplemental Material, sj-pdf-1-tva-10.1177_15248380211030242 - Positive Masculinities and Gender-Based Violence Educational Interventions Among Young People: A Systematic Review
Creators: name: Pérez-Martínez, Vanesa
name: Marcos-Marcos, Jorge
name: Cerdán-Torregrosa, Ariadna
name: Briones-Vozmediano, Erica
name: Sanz-Barbero, Belen
name: Davó-Blanes, MCarmen
name: Daoud, Nihaya
name: Edwards, Clarie
name: Salazar, Mariano
name: La Parra-Casado, Daniel
name: Vives-Cases, Carmen
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-1-tva-10.1177_15248380211030242 for Positive Masculinities and Gender-Based Violence Educational Interventions Among Young People: A Systematic Review by Vanesa Pérez-Martínez, Jorge Marcos-Marcos, Ariadna Cerdán-Torregrosa, Erica Briones-Vozmediano, Belen Sanz-Barbero, MCarmen Davó-Blanes, Nihaya Daoud, Clarie Edwards, Mariano Salazar, Daniel La Parra-Casado and Carmen Vives-Cases in Trauma, Violence, & Abuse
Recognition of Clostridium difficile PCR-ribotypes 001, 027 and 126/078 using an extended MALDI-TOF MS system
Creators: name: Reil, M.
name: Erhard, M.
name: Kuijper, Ed J.
name: Kist, Manfred
name: Zaiß, Henning
name: Witte, Wolfgang
name: Gruber, H.
name: Borgmann, S.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2011
Subjects: subject: Humans
subject: Germany/epidemiology
subject: Databases Protein
subject: Species Specificity
subject: Incidence
subject: Polymerase Chain Reaction
subject: Feces/microbiology
subject: Bacterial Typing Techniques/methods
subject: Clostridium difficile/classification
subject: Clostridium difficile/isolation & purification
subject: Enterocolitis Pseudomembranous/epidemiology
subject: Enterocolitis Pseudomembranous/microbiology
subject: Ribotyping
subject: Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization/methods
subject: 610 Medizin

description: During the last decade, Clostridium difficile infection (CDI) increased markedly inside as well as outside of hospitals. In association with the occurrence of new hypervirulent C. difficile strains, CDI became more important. Until now typing of C. difficile strains has been enabled by PCR-ribotyping. However, this method is restricted to specialized laboratories combined with high maintenance cost. Therefore, we tested MALDI-TOF mass spectrometry for typing of C. difficile to provide a fast method for surveillance of CDI. Using a standard set of 25 different C. difficile PCR ribotypes a database was made by different mass spectra recorded in the SARAMIS™ software (AnagnosTec, Zossen, Germany). The database was validated with 355 C. difficile strains belonging to 29 different PCR ribotypes collected prospectively from all submitted feces samples in 2009. The most frequent PCR ribotypes were type 001 (70%), 027 (4.8%) and 078/126 (4.7%). All three types were recognized by MALDI-TOF MS. We conclude that an extended MALDI-TOF system was capable to recognize specific markers for ribotypes 001, 027 and 078/126 allowing an effective identification of these strains.
Enhanced passive safety surveillance of standard-dose and high-dose influenza vaccines in Finland and Germany 2023–24 season
Creators: name: de Avila Machado, Marina Amaral
name: Gallo, Sophie
name: Goldstein, Alexander
name: Vachhani, Parth
name: Byrareddy, Reddappa Maniganahally
name: Kantele, Anu
name: Välimaa, Hanna
name: Schelling, Jörg
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Enhanced Passive Safety Surveillance was used to detect safety signals before the peak period of immunization with quadrivalent inactivated influenza vaccines (IIV4) in Finland (standard dose [SD]) and Germany (high dose [HD]) in the 2023–24 season. The primary objective was to evaluate adverse drug reactions (ADRs) occurring ≤7 days following IIV4 vaccination. Enrolled participants were vaccinated in routine clinical care settings and encouraged to report ADRs. Exposure data and ADR reports were collected in a near real-time manner using an electronic system. Vaccinee reporting rate (RR) with 95% confidence interval (CI) was calculated as the number of vaccinees reporting ≥ 1 ADR divided by total number of vaccinees. In Finland for SD-IIV4, among 1,003 vaccinees aged ≥ 6 months, 81 reported a total of 192 suspected ADRs occurring ≤ 7 days following vaccination (vaccinee RR 8.08%; 95% CI 6.46, 9.94). In Germany for HD-IIV4, among 1,075 vaccinees aged ≥ 60 years, 15 reported 46 ADRs that occurred in ≤ 7 days of vaccination (vaccinee RR 1.40%; 95% CI 0.78, 2.29). No safety signal was detected during this surveillance. The 2023–24 season surveillance did not suggest any clinically significant changes in safety profile compared with previously reported safety data for SD-IIV4 and HD-IIV4.
Infektionsschutzgesetz
Creators: name: Nassauer, Alfred
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2010
Subjects: subject: Infektionsschutzgesetz
subject: IfSG
subject: 610 Medizin

description: Maßnahmen gegen gemeingefährliche und übertragbare Krankheiten sind gem. Art. 74 Nr. 19 GG Gegenstand der konkurrierenden Gesetzgebung (Recht der Länder zur Gesetzgebung, solange der Bund nicht tätig wird). Von seiner Möglichkeit zur materiell-rechtlichen Regelung hat der Bundestag erstmals 1961 Gebrauch gemacht und seinerzeit das Bundes-Seuchengesetz (BSeuchG) verabschiedet. Dieses war stark von Kontrollelementen geprägt und zuletzt in großen Teilen medizinisch-fachlich veraltet. Anfang 2001 wurden deshalb das BSeuchG und das ebenfalls reformbedürftige Geschlechtskrankheitengesetz aus dem Jahr 1953 durch das Infektionsschutzgesetz (IfSG) abgelöst, dessen Kernaussagen anschließend erläutert werden. Die Notwendigkeit, die Materie gesetzlich zu regeln, ist in erster Linie durch die Tatsache begründet, dass die Erreger von Infektionskrankheiten sehr oft direkt von Mensch zu Mensch oder auch durch tierische Vektoren oder Lebensmittel auf Menschen übertragen werden können und individualmedizinische Maßnahmen allein eine Epidemie, einen Ausbruch oder schlicht die Infektion weiterer Einzelpersonen nicht wirksam verhindern können. Damit sind die Verhütung, Bekämpfung und Kontrolle übertragbarer Krankheiten eine öffentliche Aufgabe. In vielen Staaten wurden weltweit vergleichbare Regelungen umgesetzt.
Homeland as a Site of Trauma in Selected Short Stories by Edwidge Danticat
Creators: name: Abbady, Amel
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Psychic trauma
subject: Haitian Americans

description: The main objective of this article is to examine the representation of ʻhomelandʼ in three short stories by Caribbean-American writer Edwidge Danticat: “The Book of the Dead,” “Night Talkers,” and “The Gift.” All three stories represent Haitian migrants in the multi-cultural setting of the United States. A central theme that connects these stories is that of trauma and its physical and psychological repercussions on both victims and perpetrators. In the majority of earlier Caribbean migration narratives, the return to homeland is utilized to allow characters either to “confront the traumatic experience of historical violence and to finally begin the process of healing from it,” or to “[recover] an empowering cultural past” (Richardson 37, 41). However, Danticat problematizes her return narratives by presenting Haiti as a site of perpetual trauma rather than a site of healing. A close reading of Danticatʼs work shows unwillingness to heal from the wounds of the past. Drawing on the intersections between literary trauma theory and psychoanalysis this paper argues that, by establishing Haiti as a site of repetitive traumatic experiences, Danticat resists the perception of ʻreturnʼ as a healing and empowering act.
J.M. Coetzee’s ‘Jesus’ Trilogy: A Search for Answers
Creators: name: Nashef, Hania
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Coetzee, J. M., 1940-
subject: Childhood of Jesus (Coetzee, J. M.)

description: The 2019 novel by the South African-Australian Nobel laureate, J M Coetzee, The Death of Jesus, is a third book in a sequence that includes Jesus in its title; like its predecessors it follows the lives of a recently constructed family in the dystopian Spanish-speaking towns of Novilla and Estrella. The surreal trilogy, which began with The Childhood of Jesus (2013), and then The Schooldays of Jesus (2016), presents us with unreal worlds, leaving us searching for meaning. This fable-like fantasy, which expands the author’s ‘late style’, challenges the genre of fiction itself. Typical of late style, the trilogy resists closure and resolution. The debated ideas are generated by characters who were forced to forsake their memories and histories. Even though the protagonists begin to embody the very ideas they debate, answers are not forthcoming.
Targeting of a chlamydial protease impedes intracellular bacterial growth.
Creators: name: Christian, Jan G.
name: Heymann, Julia
name: Paschen, Stefan A.
name: Vier, Juliane
name: Schauenburg, Linda
name: Rupp, Jan
name: Meyer, Thomas F.
name: Häcker, Georg
name: Heuer, Dagmar
Publisher: name: Robert Koch-Institut
Year: 2011
Subjects: subject: 610 Medizin

description: Chlamydiae are obligate intracellular bacteria that propagate in a cytosolic vacuole. Recent work has shown that growth of Chlamydia induces the fragmentation of the Golgi apparatus (GA) into ministacks, which facilitates the acquisition of host lipids into the growing inclusion. GA fragmentation results from infection-associated cleavage of the integral GA protein, golgin-84. Golgin-84-cleavage, GA fragmentation and growth of Chlamydia trachomatis can be blocked by the peptide inhibitor WEHD-fmk. Here we identify the bacterial protease chlamydial protease-like activity factor (CPAF) as the factor mediating cleavage of golgin-84 and as the target of WEHD-fmk-inhibition. WEHD-fmk blocked cleavage of golgin-84 as well as cleavage of known CPAF targets during infection with C. trachomatis and C. pneumoniae. The same effect was seen when active CPAF was expressed in non-infected cells and in a cell-free system. Ectopic expression of active CPAF in non-infected cells was sufficient for GA fragmentation. GA fragmentation required the small GTPases Rab6 and Rab11 downstream of CPAF-activity. These results define CPAF as the first protein that is essential for replication of Chlamydia. We suggest that this role makes CPAF a potential anti-infective therapeutic target.
Review of Humberto Beck, The Moment of Rupture: Historical Consciousness in Interwar German Thought (University of Pennsylvania Press, 2019)
Creators: name: Gelderloos, Carl
Publisher: name: Humanities Commons
Year: 2020

description: A review of Humberto Beck, The Moment of Rupture: Historical Consciousness in Interwar German Thought (University of Pennsylvania Press, 2019), which appeared in German Quarterly 93.3 (2020). This is the accepted version; please refer to the published version if citing.
Time trends of syphilis and HSV-2 co-infection among men who have sex with men in the German HIV-1 seroconverter cohort from 1996–2007
Creators: name: Spielmann, Nadine
name: Münstermann, Dieter
name: Hagedorn, Hans-Jochen
name: Heiden, Matthias An Der
name: Houareau, Claudia
name: Gunsenheimer-Bartmeyer, Barbara
name: Kücherer, Claudia
name: Keeren, Katrin
name: Hamouda, Osamah
name: Marcus, Ulrich
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2010
Subjects: subject: Adult
subject: Humans
subject: Germany/epidemiology
subject: Male
subject: Incidence
subject: Time Factors
subject: Prospective Studies
subject: HIV Seropositivity/epidemiology
subject: Syphilis/epidemiology
subject: HIV-1/immunology
subject: HIV Seropositivity/complications
subject: Homosexuality Male/statistics & numerical data
subject: Herpes Genitalis/complications
subject: Herpes Genitalis/epidemiology
subject: Herpesvirus 2 Human/immunology
subject: Poisson Distribution
subject: Syphilis/complications
subject: 610 Medizin

description: Objectives: Numbers of newly diagnosed HIV infections among men who have sex with men (MSM) in Germany increased after the year 2000. We sought to explore trends in STI co-infections around the time of HIV seroconversion in patients from the German HIV-1 seroconverter cohort from 1996–2007. Methods: MSM from the cohort were included for secondary analysis, if seroconversion occurred between 1996 and 2007 and if a blood sample taken within 2 y after HIV infection was available for further testing. Samples were tested for antibodies against Treponema pallidum and HSV-2. A classification system was developed to assign the chronology of syphilis and HIV-1 infection. Results: Data of 1052 MSM were eligible for analysis. Overall seroprevalence of syphilis markers was 26%, increasing from 10% (1996–1999) to 35% (2005). Among HIV seroconverters with positive syphilis antibodies, 32% (n=88) were rated as having had coincident infections with HIV and syphilis. Coincident syphilis infection at HIV diagnosis increased substantially (p
Additional file 14 of Cannulated screws versus dynamic hip screw versus hemiarthroplasty versus total hip arthroplasty in patients with displaced and non-displaced femoral neck fractures: a systematic review and frequentist network meta-analysis of 5703 patients
Creators: name: Ramadanov, Nikolai
name: Jóźwiak, Katarzyna
name: Hauptmann, Michael
name: Lazaru, Philip
name: Marinova-Kichikova, Polina
name: Dimitrov, Dobromir
name: Becker, Roland
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 14: Forest plot of mortality (displaced femoral neck fractures only). CS, cannulated screw; DHS, dynamic hip screw; HA, hemiarthroplasty; THA, total hip arthroplasty; OR, odds ratio; CI, confidence interval.
Human papillomavirus vaccination in rural Malawi: Identifying factors associated with vaccine uptake using a community-based household survey
Creators: name: Moucheraud, Corrina
name: Kalande, Pericles
name: Chibaka, Symon
name: Phiri, Khumbo
name: Makwaya, Amos
name: Duah, Maame
name: Li, Mei
name: Liu, Muxin
name: Hoffman, Risa M.
name: Phiri, Sam
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Uptake of the human papillomavirus (HPV) vaccine is suboptimal globally. Effective interventions are needed to meet the global goal of vaccinating 90% of girls against HPV, and this requires a robust understanding of barriers to vaccine uptake. Using a household survey in three communities of Malawi with parents/guardians of girls aged 9–13 years, we collected and analyzed data about intervention-amenable factors hypothesized to be associated with girls’ HPV vaccination status. The 299 parent/guardian respondents provided information on 382 girls aged 9–13 years, of whom 39.0% (n = 149) had received ≥ 1 dose of the HPV vaccine. More than half of parents/guardians were concerned about the HPV vaccine’s safety. Greater HPV vaccine hesitancy was associated with having an unvaccinated daughter in adjusted multilevel models (aOR 0.69 [95% CI 0.50–0.93]). Higher odds of being vaccinated were found among daughters of respondents with greater knowledge about the HPV vaccine and who knew someone who had cervical cancer. Speaking with more people about cervical cancer/HPV vaccination, and perceiving that other parents are vaccinating their daughters against HPV, were strongly associated with daughters’ HPV vaccination status (aOR 2.03 [95% CI 1.59–2.62] and 3.68 [95% CI 1.97–7.18, respectively). Most parents/guardians had not experienced, or did not anticipate experiencing, challenges accessing HPV vaccination services, but those who did also had daughters with lower odds of vaccination. Interventions that leverage social networks and norms, increase confidence in the vaccine’s safety, and work to improve access to HPV vaccination services, may increase coverage of the HPV vaccine in Malawi.
Additional file 1 of How is GPS used? Understanding navigation system use and its relation to spatial ability
Creators: name: Topete, Alexis
name: He, Chuanxiuyue
name: Protzko, John
name: Schooler, Jonathan
name: Hegarty, Mary
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Individual item descriptive statistics for the GPS scales used, and correlations for each of the measures in the Virtual SILCton (in-person) study.
Bullied Young Women, Virginia Woolf's Sex Japes, and Modernist Sociability in the Time of #MeToo
Creators: name: Zemgulys, Andrea P.
Publisher: name: Johns Hopkins University Press
Year: 2023
Subjects: subject: Tennyson, Alfred Tennyson, Baron, 1809-1892
subject: Actors
subject: Terry, Ellen, Dame, 1847-1928
subject: Satire
subject: Bloomsbury group
subject: Costume
subject: Woolf, Virginia, 1882-1941
subject: Riviere, Joan, 1883-1962
subject: MeToo movement
subject: Garnett, Angelica

description: Salacious rumors about Alfred Tennyson's conduct with young women inspired Virginia Woolf's satirical depiction of Tennyson and Ellen Terry in her draft and produced play -Freshwater.- In considering whether Woolf's satire silences the whispers of Victorian women and/or corrects salacious rumor-mongering, this essay decides that the play more certainly harmed Woolf's teen niece, Angelica Bell, who played the role of Ellen Terry for the entertainment of adults, and offers that features of modernism writ large (sexually-progressive artists' circles and economic-libidinal understandings of social life, with reference to psychoanalyst Joan Riviere's "Women as Masquerade") invigorated harmful customs of sociability that are now being brought to critical attention by #MeToo. Posted on the "Orientations" forum of Modernism/modernity Print+, the essay frames its content with the perspective of a feminist scholar and instructor.
Optimization and Control in Procedural Modeling
Creators: name: Krs, Vojtech
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Computer graphics

description: Procedural modeling is a powerful technique used in computer graphics to create geometric models. Instead of manual geometry definition, models are generated implicitly from a set of rules and parameters. Procedural systems have found widespread use in generating content for games, film, and simulation of natural phenomena. Their strength comes from the ability to automatically generate large amount of varied geometry. One of their drawbacks is lack of control because a small change in input parameters often causes large changes in the generated model.
In this work we present three novel procedural systems, investigate different forms of control, namely simulation and optimization, and discuss them in terms of general procedural modeling workflow. First we show modeling of 3D objects with arbitrary topology via erosion and deposition simulation controlled by Smoothed Particle Hydrodynamics. Next, we present an algorithm for generating 3D curves using 2D sketches and contextual geometry. Finally, we propose a novel procedural system capable of generating arbitrary type of geometry with respect to user-defined constraints.
We show that these systems can be controlled via several means and identify common preconditions that facilitate control: maximizing interactivity and amount of structured information input, minimizing unexpected behaviour, and local control akin to traditional modeling.
Immunogenicity and safety of 1 versus 2 doses of quadrivalent-inactivated influenza vaccine in children aged 3–8 years with or without previous influenza vaccination histories
Creators: name: Wen, Feng
name: Liu, Sheng
name: Zhou, Li
name: Zhu, Yinbiao
name: Wang, Wenjuan
name: Wei, Mingwei
name: Xu, Xinglong
name: Liu, Yan
name: Shuai, Qi
name: Yu, Jun
name: Jing, Pengfei
name: Li, Jingxin
name: Zhu, Fengcai
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: This study assessed the immunogenicity and safety of a quadrivalent influenza split-virion vaccine (IIV4) in children with and without prior influenza vaccination. An open-label, phase IV clinical trial was conducted in healthy children aged 3–8 years in Pizhou, Jiangsu Province, China. Children with ≥2 doses of prior influenza vaccination (Influenza Vaccination Group) and those with no prior vaccination (Influenza Vaccine-naïve Group) were given two doses of IIV4, 4 weeks apart. The primary immunogenicity endpoints were seroprotection rates (SPRs) of hemagglutination inhibition antibody 28 days after each dose against influenza A/H1N1, A/H3N2, B/Yamagata (BY), and B/Victoria (BV). Safety endpoints included adverse events (AEs) within 28 days and serious adverse events (SAEs) within 6 months. Between September 19–25, 2021, 278 participants were screened, and 240 were enrolled (120 per group). In the Influenza Vaccination Group, SPRs after the 2nd dose were 98.28%, 92.24%, 99.14%, and 87.93%, similar to those after the 1st dose (all p > .05). In the Influenza Vaccine-naïve Group, SPRs after the 2nd dose were 99.12%, 96.49%, 99.12%, and 92.11%, significantly higher than after the 1st dose (p < .001 for all strains except BY, p = .070). Most AEs were mild or moderate, with no serious AEs related to the vaccine. Children aged 3–8 years with prior influenza vaccination need only one dose of IIV4, while those without prior vaccination require two doses. ClinicalTrials.gov, the identifier is NCT05144464.
Structural and Kinetic Comparison of Acetolactate Synthase and Acetohydroxyacid Synthase from Klebsielle pneumoniae
Creators: name: Latta, Alexander Jon
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Biochemistry and cell biology not elsewhere classified
Catalysis and mechanisms of reactions
Characterisation of biological macromolecules
Crystallography

description: Acetolactate synthase (ALS) and acetohydroxyacid synthase (AHAS) are two thiamin diphosphate (ThDP)-dependent enzymes that catalyze the formation of acetolactate from two molecules of pyruvate. In addition to acetolactate, AHAS can catalyze the formation of acetohydroxybutyrate from pyruvate and α-ketobutyrate. When formed by AHAS, these compounds are important precursors to the essential amino acids valine and isoleucine. Conversely, ALS forms acetolactate as a precursor to 2,3‑butanediol, a product formed in an alternative pathway to mixed acid fermentation. While these enzymes catalyze the same reaction, they have been found to be quite different. Such differences include: biological function, pH optimum, cofactor requirements, reaction kinetics and quaternary structure. Importantly, AHAS has been identified as the target of the widely-used sulfonylurea and imidazolinone herbicides, which has led to many structural and kinetic studies on AHAS enzymes from plants, bacteria, and fungi. ALS, on the other hand, has only been identified in bacteria, and has largely not seen such extensive characterization. Finally, although some bacteria contain both enzymes, they have never been studied in detail from the same organism. Here, the ALS and AHAS enzymes from Klebsiella pneumoniae were studied using steady-state kinetic analyses, X-ray crystallography, site-directed and site‑saturation mutagenesis, and cell growth complementation assays to i) compare the kinetic parameters of each enzyme, ii) compare the active sites to probe their differences in substrate profile and iii) test the ability of ALS to function in place of AHAS in vivo.