cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The pH-dependence of efflux ratios determined with bidirectional transport assays across cellular monolayers
Creators: name: Kotze, Soné
name: Goss, Kai-Uwe
name: Ebert, Andrea
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 540

description: MDCK/Caco-2 assays serve as essential in vitro tools for evaluating membrane permeability and active transport, especially mediated by P-glycoprotein (P-gp). Despite their utility, challenges remain in quantifying active transport and using the efflux ratio (ER) to determine intrinsic values for active efflux. Such an intrinsic value for P-gp facilitated efflux necessitates knowing whether this transporter transports the neutral or ionic species of a compound. Utilising MDCK-MDR1 assays, we investigate a method for determining transporter substrate fraction preference by studying ER pH-dependence for basic, acidic and non-dissociating compounds. These results are compared with model fits based on various assumptions of transporter species preference. As an unexpected consequence of these assays, we also give evidence for an additional influx transporter at the basolateral membrane, and further extend our model to incorporate this transport. The combined influences of paracellular transport, the previously unaccounted for basolateral influx transporter, as well as potential pH effects on the transporter impedes the extraction of intrinsic values for active transport from the ER. Furthermore, we determined that using inhibitor affects the measurement of paracellular transport. While clear indications of transporter species preference remain elusive, this study enhances understanding of the MDCK system.
Leonardiella machadoi Kontschán 2006, sp. n.
Creators: name: Kontschán, J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Trachyuropodidae
Leonardiella
Leonardiella machadoi

description: Leonardiella machadoi sp. n.
(Figs 8–13)
Diagnosis: Characteristic idiosoma with several strong setiform setae on marginal shield and on central and caudal part of dorsal shield. Ventral and dorsal side without ornamentation. Marginal part of dorsal shield with a wide and wellsclerotised line. Genital shield of females without ornamentation and scutiform.
Description: Female. Length of idiosoma 910 µm, width (in the middle of idiosoma) 630 µm (n = 1). Shape characteristic, posterior margin rounded, anterior margin with vertex.
Dorsal side (Fig. 8): Dorsal shield with two types of setae. Central and caudal part with strong, smooth and spiniform setae, while anteromarginal part with T-shaped setae. Ornamentation of dorsal and marginal shields lacking, marginal setae similar to dorsal ones.
Ventral side (Fig. 9): Ventral shield without ornamentation. All ventral setae not clearly visible. Several short T-shaped setae on caudal part of ventral shield. Marginal setae short, thin and spiniform. Sternal setae not clearly visible. One pair of spiniform setae under coxae 4 near metapodal lines. Genital shield between anterior margin of sternal shield and coxae 4, large, scutiform and without ornamentation.
Gnathosoma (Fig. 10): Corniculi short, horn-like, laciniae with four thicker branches and bearing many thinner branches.Gnathosomal setae are the following: h1 and h3 short, smooth and setiform, h2 long, smooth and setiform, h4 long, apically serrated. Tritosternum with four branches, carrying many thinner branches (Fig. 11). Base of epistome not clearly visible, anterior part with long hairs (Fig. 12). Chelicerae not clearly visible, apical part as shown in Fig. 13.
Male, deuteronymph, protonymph and larva unknown.
Material examined: holotype: female, Angola, Dundo, foret R. Casulo May 1980, leg. SZABÓ.
Etymology: The species is dedicated Dr. A. DE BARROS MACHADO, who collected various materials in Angola.
Remarks: The most important differentiating characters of the new species are the strong setiform setae in dorsum and the characteristic shape of the idiosoma.
description: Published as part of Kontschán, J., 2006, Uropodina (Acari: Mesostigmata) Species From Angola, pp. 1-20 in Acta Zoologica Academiae Scientiarum Hungaricae 52 (1) on pages 4-6, DOI: 10.5281/zenodo.5731774
title: Dendrobium :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Group identity.
New Varieties of Plants
Dendrobium

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
D2.4 AgriBIT Open APIs and interfaces (rev. 1)
Creators: name: Vella, Giuseppe
name: Scrima, Piero
Publisher: name: Zenodo
Year: 2022

description: This document addresses the description of the first version of AgriBIT Open APIs and interfaces. In the first place a technological context is given, describing the concept of Application Program interfaces (APIs) and the OpenAPI specification, and providing an overview on OGC WMS e WFS standards. These standards allow, by HyperText Transfer Protocol (HTTP) interface, to provide geospatial raster services and vector geospatial service. After these introductions on the main technologies and standards involved, the list of AgriBIT APIs for third parties’ users is presented. The APIs are splitted in three major macro areas: Precision Agriculture (PA) services (GNSS enabled services), GNSS enablers services and Big Data Analytics (BDA) services. The first area addresses all the services related to target of the project itself, in fact with this information a third party’s users can retrieve the main elaboration of the project to help and advice farmers in order to monitoring the crop growth, optimize activities of: irrigation, tillage and the fertilization; retrieve information and advices on the possible pests and diseases of the crops. GNSS enablers services enable the invoker to retrieve information on the parcels, as for PA services. The invoker should be the owner of the parcel or a user specifically authorized by the latter. GNSS enablers services also provides sensors data collected on the field, along with the coordinates in GeoJSON of the field border and geometry. Finally, the Big Data Analytics services (BDA) empower the third party’s users by giving them the possibility to work with Big Data Analytics provided by ALIDA platform. BDA are designed using a graphical user interface (GUI). Once the workflow and the analytics are built the APIs allow invoker to manage it, and also to check the status and the associated resource, such as datasets, machine learning models, data sources and applications. In the conclusion paragraph the importance of this document for the coordination and the development of the AgriBIT components is stated.
Neohadria delecta Freytag 2007
Creators: name: Powell, Erin C.
name: Halbert, Susan E.
name: Deeter, Lily
name: Keller, Oliver
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Neohadria
Neohadria delecta

description: Neohadria delecta Freytag, 2007
Neohadria delecta Freytag, 2007: 395
Holotype: 1 ♁. DOMINICAN REPUBLIC;/ Barahona, Filipinas, Larimar / Mine, 3300 ft, 12-IV-1997 // blacklight trap / R. E. Woodruff // [on red with black rectangle] Holotype/ [hw] Neohadria / delecta/ Freytag[/hw] // [upside down barcode label] FSCA 00070598.
Conservation status: Good condition; point mounted; dissected abdomen in micro vial pinned under second label (Fig. 86).
description: Published as part of Powell, Erin C., Halbert, Susan E., Deeter, Lily & Keller, Oliver, 2023, An annotated and illustrated catalog of the primary type material of Hemiptera deposited in the Florida State Collection of Arthropods, pp. 1-107 in Zootaxa 5355 (1) on page 54, DOI: 10.11646/zootaxa.5355.1.1, http://zenodo.org/record/10022197
Strategies for modeling aging and age-related diseases
Creators: name: Jothi, D.
name: Kulka, Linda Anna Michelle
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 540

description: The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and age-related diseases like Parkinson’s, and Alzheimer’s. The established patient-derived disease models mimic disease pathology and can be used to design drugs for aging and age-related diseases. However, the age and genetic mutations of the donor cells, the employed reprogramming, and the differentiation protocol might often pose challenges in establishing an appropriate disease model. In this review, we will focus on the various strategies for the successful reprogramming and differentiation of patient-derived cells to disease models for aging and age-related diseases, emphasizing the accuracy in the recapitulation of disease pathology and ways to overcome the limitations of its potential application in cell replacement therapy and drug development.
Phylogenetic relationship and plant life stage but not biogeographic history mediate priority effects of European grassland plants
Creators: name: Dieskau, Julia
name: Hensen, Isabell
name: Eisenhauer, Nico
name: Gaberle, Ingmar
name: Durka, Walter
name: Lachmuth, Susanne
name: Auge, Harald
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 580

description: The timing and order of species arrival have been shown to be a significant factor in the assembly of biotic communities. Therefore, understanding priority effects, which refer to the impact of an early-arriving species on a later-arriving one, can help us better predict community assembly processes. However, little is known about the role of phylogenetic distance (PD) in priority effects and how they are mediated by the biogeographic history (BH) and the life stages (LSs) of interacting species. To shed light on the role of PD in priority effects, we conducted a multispecies greenhouse experiment. We created 10 allopatric and 10 sympatric species pairs, representing a PD gradient between early- and late-arriving species from 5 to 270 Myr in evolutionary history and tested the priority effect of early-arriving species on the late-arriving species at multiple LSs. We found evidence of stronger competition between closely related species, as late-arriving plants produced less above-ground biomass when the PD was low. However, priority effects varied across the development of late-arriving plants, as there were no effects on seedling emergence and survival, independent of PD. Regardless of PD, the pairs of allopatric and sympatric species did not differ in their responses. Synthesis. While many studies have produced contradictory results regarding the effect of PD on plant–plant interactions, our study provides experimental evidence that priority effects can be stronger when PD is small. This effect was independent of BH but varied across different LSs of late-arriving plants. The dependence of the effect of PD on the LS of late-arriving species highlights the importance of the timing of interactions for the assembly of plant communities, which could also have significant implications for the fields of invasion and restoration ecology.
FindPOTATOs: Minor Planet Observation Linking Software
Creators: name: Nugent, C. R.
name: Tan, Nicole J.
name: Bauer, James M.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: For minor planet observations to be archived and used by the scientific community, observations of individual objects must be linked together into groups called tracklets. This linking is nontrivial, as linking software must find real tracklets in noisy data within a reasonable amount of time. We describe FindPOTATOs, a linking software written in Python that can assemble minor planet tracklets. With the appropriate parameters, FindPOTATOs assembles tracklets for a variety of objects, including close-approaching near-Earth objects and trans-Neptunian objects. FindPOTATOs is ideal for processing data sets taken at small observatories, processing archival data, or finding tracklets of minor planets on unusual orbits. This paper describes the code structure, usage, and validation.
description: 7 pages, 4 figures
Oplitis BERLESE 1884
Creators: name: Kontschán, J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Trachyuropodidae
Oplitis

description: Oplitis BERLESE, 1884
The revision and the identification key to the species groups and the species were made by HIRSCHMANN (1991).
The main characteristics of the genus Oplitis are the following (HIRSCHMANN 1993): Idiosoma: Shape oval or circular, idiosoma small. Gnathosoma: Corniculi short and horn-like. Laciniae with some branches and covered by long hairs. Three to five serrated branches on the base of epistome. Tritosternum with serrated margin. Chelicerae with nodus.
Oplitis species are known from Europe, North and South America, and Asia, and they are widely distributed in the west and east Ethiopian region (WIŚNIEWSKI 1993).
Type species: Oplitis paradoxa (BERLESE, 1884)
description: Published as part of Kontschán, J., 2006, Uropodina (Acari: Mesostigmata) Species From Angola, pp. 1-20 in Acta Zoologica Academiae Scientiarum Hungaricae 52 (1) on page 6, DOI: 10.5281/zenodo.5731774
Paraxenylla Murphy 1965
Creators: name: Queiroz, Gabriel C.
name: Deharveng, Louis
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Hypogastruridae
Paraxenylla

description: Paraxenylla Murphy, 1965
Xenylla (Paraxenylla) Murphy, 1965
Haloxenylla Gama & Deharveng, 1984
Type species Xenylla (Paraxenylla) mangle Murphy, 1965
Diagnosis of the genus (after Palacios-Vargas & Janssens 2006, modified). Habitus of Xenylla. Length 0.36- 1.5 mm. Body with blue pigment. PAO absent. 5+5 eyes. Mouthparts strongly modified. Mandible head narrow and subparallel distally. Maxillary ungulum reduced. Labral chaetae 2, 4–7/5, 5, 4. Ant IV with four thickened S-chaetae, one S-microchaeta and one subapical organ, the apical bulb simple or trilobed. Empodial appendage absent. Furcula developed, mucro present. Tenaculum with 2-4 teeth on each ramus. Anus terminal, abdominal segment VI as a truncate cone. Anal spines absent.
description: Published as part of Queiroz, Gabriel C. & Deharveng, Louis, 2008, Description of a new species of Paraxenylla (Collembola, Hypogastruridae) from Brazil, with comments on the genus, pp. 1-8 in Zootaxa 1858 on page 2, DOI: 10.5281/zenodo.183626
Dust production through collisions between small bodies: an application to the G-ring arc
Creators: name: Lattari, V.
name: Sfair, R.
name: Siqueira, P. B.
name: Schäfer, C. M.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The G-ring arc of Saturn, confined by the 7:6 corotation eccentric resonance with Mimas, is primarily composed of micrometric particles. These particles, significantly influenced by the solar radiation pressure, are subject to rapid depletion. This study investigates a mechanism for dust replenishment in the arc, specifically analyzing collisions between macroscopic bodies and the satellite Aegaeon. Utilizing N-body and Smoothed particle hydrodynamics (SPH) simulations, we assess the dust generation from these impacts, with a focus on the most likely collision parameters derived from the N-body simulations. Our findings indicate that, while collisions among macroscopic bodies are inefficient for dust production, impacts involving Aegaeon are substantially more effective, providing conservative lower limits for dust generation. This mechanism, in conjunction with the natural decay processes and continuous dust generation from impacts, potentially keeps the arc population over thousands of years with a possible variation in brightness.
The frozen elephant trunk technique in acute aortic dissection: the ultimate solution? : an institutional experience
Creators: name: Wisniewski, Konrad
name: Dell'Aquila, Angelo Maria
name: Motekallemi, Arash
name: Oberhuber, Alexander
name: Schäfers, Johannes F.
name: Marchiori, Elena
name: Weber, R.
name: Martens, S.
name: Rukosujew, A.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Objective: Acute aortic dissection remains a serious emergency in the field of cardiovascular medicine and a challenge for cardiothoracic surgeons. In the present study, we seek to compare the outcomes of different surgical techniques in the repair of type A acute aortic dissection. Methods: Between April 2015 and May 2023, 213 patients (82 women, aged: 63.9 ± 13.3 years) with acute aortic dissection (205 type A and 8 non-A-non-B dissections) underwent surgical treatment in our department. A total of 45 patients were treated with the frozen elephant trunk (FET) technique supported by the Thoraflex™ Hybrid prosthesis, 33 received total aortic arch replacement (TAR)—standard or conventional elephant trunk—treatment, and 135 were treated with hemiarch replacement (HR). Aortic arch surgery was performed in most patients under moderate hypothermic (28°C on average) circulatory arrest, with selective antegrade cerebral perfusion through the right axillary artery. Results: The rates of early mortality were 17.8% (38 perioperative deaths) in the whole population, 8.9% in the FET group of patients, and 33% and 17% in the TAR and HR group of patients, respectively (P-value 0.025). The rate of spinal cord injury was 2.3% (five patients), and a paresis of recurrent laryngeal occurred in 3.7% of patients (seven patients, four were treated with FET). Permanent neurological dysfunction occurred in 27 patients (12.7%). After a mean follow-up of 3 years, the rate of mid-term mortality of discharged patients was 19.4% (34 deaths: 7 FET, 4 TAR, and 23 HR) and the overall mortality rate was 33.8% [72 deaths: 11 FET (24.4%); 15 TAR (45.4%); 46 HR (34.1%)]. A total of 8 patients (17.8%) in whom FET was applied received additional endovascular treatment in the descending aorta. Conclusions: In our institutional experience, we found that the frozen elephant trunk technique with a high-end Thoraflex Hybrid prosthesis proved its surgical suitability in the treatment of acute aortic dissection with favorable outcomes. The FET technique and our perioperative management led to comparable neurological outcomes and reduced mortality rates in these emergency cases.
Wave propagation in three-dimensional fractional viscoelastic infinite solid body
Creators: name: Jelić, Slađan
name: Zorica, Dušan
Publisher: name: arXiv
Year: 2024
Subjects: subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: In order to analyze the wave propagation in three-dimensional isotropic and viscoelastic body, the Cauchy initial value problem on unbounded domain is considered for the wave equation written as a system of fractional partial differential equations consisting of equation of motion of three-dimensional solid body, equation of strain, as well as of the constitutive equation, obtained by generalizing the classical Hooke's law of three-dimensional isotropic and elastic body by replacing Lamé coefficients with the relaxation moduli to account for different memory kernels corresponding to the propagation of compressive and shear waves. By the use of the method of integral transforms, namely Laplace and Fourier transforms, the displacement field, as a solution of the Cauchy initial value problem, is expressed through Green's functions corresponding to both compressive and shear wave propagation. Two approaches are adopted in solving the Cauchy problem: in the first one the displacement field is expressed through the scalar and vector fields, obtained as solutions of wave equations which are consequences of decoupling the wave equation for displacement field, while in the second approach the displacement field is obtained by the action of the resolvent tensor on the initial conditions. Fractional anti-Zener and Zener model I$^{{}^{+}}$ID.ID, as well as fractional Burgers model VII, as representatives of models yielding infinite and finite wave propagation speed, are used in numerical calculations and graphical representations of Green's functions and its short and large time asymptotic behavior.
Neohadria grisea Freytag 2007
Creators: name: Powell, Erin C.
name: Halbert, Susan E.
name: Deeter, Lily
name: Keller, Oliver
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Neohadria
Neohadria grisea

description: Neohadria grisea Freytag, 2007
Neohadria grisea Freytag, 2007: 395
Holotype: 1 ♁. DOMINICAN REPUBLIC;/ Barahona, Filipinas, Larimar / Mine, 3300 ft, 12-IV-1997 // blacklight trap / R. E. Woodruff // [on red with black rectangle] Holotype/ [hw] Neohadria / grisea/ Freytag[/hw] // [upside down barcode label] FSCA 00070599.
Conservation status: Good condition; point mounted; dissected abdomen in micro vial pinned under second label (Fig. 87).
description: Published as part of Powell, Erin C., Halbert, Susan E., Deeter, Lily & Keller, Oliver, 2023, An annotated and illustrated catalog of the primary type material of Hemiptera deposited in the Florida State Collection of Arthropods, pp. 1-107 in Zootaxa 5355 (1) on pages 54-55, DOI: 10.11646/zootaxa.5355.1.1, http://zenodo.org/record/10022197
Ceropales cribrata
Creators: name: Madl, Michael
name: P, Cryptocheilus
name: D, Cyphononyx
name: H, Dichragenia
name: D, Hemipepsis
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Ceropales
Ceropales cribrata

description: Ceropales cribrata (COSTA, 1881)
Hemiceropales cribrata cibrata (COSTA, 1881): MÓCZÁR 1986a: 321 (key), 322 (figs 16-20), 331 (taxonomy, biology, Ghinda (Nigeria = Eritrea).
Ceropales cribrata cibrata (COSTA, 1881): MADL 2020: 75 (catalogue Afrotropical region).
D i s t r i b u t i o n:Ghinda.
Ceropales cribrata, which is widely distributed in the Afrotropical region, is also recorded from Ethiopia and the Palaearctic region (Saudi Arabia).
description: Published as part of Madl, Michael, P, Cryptocheilus, D, Cyphononyx, H, Dichragenia & D, Hemipepsis, 2022, A catalogue of the Pompilidae (Hymenoptera, Vespoidea) of Eritrea, pp. 225-234 in Linzer biologische Beiträge 54 (1) on page 226, DOI: 10.5281/zenodo.7507390
B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection
Creators: name: Schultheiß, Christoph
name: Willscher, Edith
name: Paschold, Lisa
name: Ackermann, Christin
name: Escher, Moritz
name: Scholz, Rebekka
name: Knapp, Maximilian
name: Lützkendorf, Jana
name: Müller, Lutz P.
name: Schulze Zur Wiesch, Julian Constantin Raimar
name: Binder, Mascha
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Chronic HCV infection leads to a complex interplay with adaptive immune cells that may result in B cell dyscrasias like cryoglobulinemia or lymphoma. While direct-acting antiviral therapy has decreased the incidence of severe liver damage, its effect on extrahepatic HCV manifestations such as B cell dyscrasias is still unclear. Methods: We sequenced B cell receptor (BCR) repertoires in patients with chronic HCV mono-infection and patients with HCV with a sustained virological response (SVR) after direct-acting antiviral therapy. This data set was mined for highly neutralizing HCV antibodies and compared to a diffuse large B cell lymphoma data set. The TKO model was used to test the signaling strength of selected B-BCRs in vitro. Single-cell RNA sequencing of chronic HCV and HCV SVR samples was performed to analyze the transcriptome of B cells with HCV-neutralizing antigen receptors. Results: We identified a B cell fingerprint with high richness and somatic hypermutation in patients with chronic HCV and SVR. Convergence to specific immunoglobulin genes produced high-connectivity complementarity-determining region 3 networks. In addition, we observed that IGHV1-69 CDR1 and FR3 mutations characterizing highly neutralizing HCV antibodies corresponded to recurrent point mutations found in clonotypic BCRs of high-grade lymphomas. These BCRs did not show autonomous signaling but a lower activation threshold in an in vitro cell model for the assessment of BCR signaling strength. Single-cell RNA sequencing revealed that B cells carrying these point mutations showed a persisting oncogenic transcriptome signature with dysregulation in signaling nodes such as CARD11, MALT1, RelB, MAPK, and NFAT. Conclusions: We provide evidence that lymphoma-like cells derive from the anti-HCV immune response. In many patients, these cells persist for years after SVR and can be interpreted as a mechanistic basis for HCV-related B cell dyscrasias and increased lymphoma risk even beyond viral elimination. Abstract
BayesEoR: Bayesian 21-cm Power Spectrum Estimation from Interferometric Visibilities
Creators: name: Sims, Peter H.
name: Burba, Jacob
name: Pober, Jonathan C.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: BayesEoR is a GPU-accelerated, MPI-compatible Python package for estimating the power spectrum of redshifted 21-cm emission from interferometric observations of the Epoch of Reionization (EoR). Utilizing a Bayesian framework, BayesEoR jointly fits for the 21-cm EoR power spectrum and a "foreground" model, referring to bright, contaminating emission between us and the cosmological signal, and forward models the instrument with which these signals are observed. To perform the sampling, we use MultiNest [arXiv:1402.0004], which calculates the Bayesian evidence as part of the analysis. Thus, BayesEoR can also be used as a tool for model selection [see e.g. arXiv:1701.03384].
Ceropales latifasciata ARNOLD 1937
Creators: name: Madl, Michael
name: P, Cryptocheilus
name: D, Cyphononyx
name: H, Dichragenia
name: D, Hemipepsis
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Ceropales
Ceropales latifasciata

description: Ceropales latifasciata ARNOLD, 1937
Ceropales (Ceropales) latifasciata ARNOLD, 1937: MÓCZÁR 1986b: 126 (key), 135 (taxonomy, lectotype designation, Asmara).
Ceropales latifasciata ARNOLD, 1937: MADL 2020: 77 (catalogue Afrotropical region).
D i s t r i b u t i o n:Asmara.
Ceropales latifasciata is also known from the Democratic Republic of the Congo, Ethiopia and Rwanda.
description: Published as part of Madl, Michael, P, Cryptocheilus, D, Cyphononyx, H, Dichragenia & D, Hemipepsis, 2022, A catalogue of the Pompilidae (Hymenoptera, Vespoidea) of Eritrea, pp. 225-234 in Linzer biologische Beiträge 54 (1) on page 226, DOI: 10.5281/zenodo.7507390
Erenumab escalation in migraine - double dose without additional benefit : a retrospective experience
Creators: name: Heintz, Simon
name: Storch, Peter
name: Burow, Philipp
name: Maier, Patricia
name: Obermann, Mark
name: Stoessel, Grit
name: Kraya, Torsten
name: Naegel, Steffen
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Erenumab is a monoclonal antibody specifically targeting the CGRP-receptor. Several studies showed efficacy and safety in patients with migraine. Less is known regarding dosage increase, especially in a difficult to treat patients. The aim of the study is to evaluate the increased dosage under real world conditions with particular focus on 70 mg non-responders. Methods: In a retrospective analysis, patients treated in tertiary headache centers (Halle or Jena, Germany) receiving 70 mg erenumab for at least 3 months with a dosage increase to 140 mg were analyzed. Data were evaluated regarding headache days, intake of acute medication, previous prophylaxis, and medication overuse. Baseline and all treatment intervals were determined as three-month periods. Results: Datasets of 52 migraine patients (90.4% women) aged between 22 and 78 years (mean 50.4 years, SD 12.1 years) were analyzed. At baseline (mean headache-days 15.67 ± 6.37) 51.9% met criteria for chronic migraine and 56% were currently overusing acute medication. While therapy with 70 mg showed significant improvement in headache days and 50% response, further improvement was not achieved for therapy escalation to 140 mg. The same applies to the secondary endpoints and covers the entire study population as well as the subgroups of chronic and episodic migraine. The 50% response of the 70 mg non-responders for escalation was only 5.14%. Conclusions: In this difficult-to-treat patient cohort we reconfirmed the effectiveness of erenumab, but could not detect any additional benefit for a dosage escalation from 70 mg to 140 mg erenumab.
Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by β-strand slippage
Creators: name: Katzschmann, Anja
name: Haupts, Ulrich
name: Reimann, Anja
name: Settele, Florian
name: Gloser-Bräunig, Manja
name: Fiedler, Erik
name: Parthier, Christoph
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 572

description: Affilin proteins, artificial binding proteins based on the ubiquitin scaffold, have been generated by directed protein evolution to yield de-novo variants that bind the extra-domain B (EDB) of oncofetal fibronectin, an established marker of tumor neovasculature. The crystal structures of two EDB-specific Affilin variants reveal a striking structural plasticity of the ubiquitin scaffold, characterised by β-strand slippage, leading to different negative register shifts of the β5 strands. This process recruits amino acid residues from β5 towards the N-terminus to an adjacent loop region and subsequent residues into β5, respectively, remodeling the binding interface and leading to target specificity and affinity. Protein backbone alterations resulting from β-strand register shifts, as seen in the ubiquitin fold, can pose additional challenges to protein engineering as structural evidence of these events is still limited and they are difficult to predict. However, they can surface under the selection pressure of directed evolution and suggest that backbone plasticity allowing β-strand slippages can increase structural diversity, enhancing the evolutionary potential of a protein scaffold.
Auplopus nigroaurantiacus
Creators: name: Madl, Michael
name: P, Cryptocheilus
name: D, Cyphononyx
name: H, Dichragenia
name: D, Hemipepsis
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Auplopus
Auplopus nigroaurantiacus

description: Auplopus nigroaurantiacus (MAGRETTI, 1884)
Agenia nigro -aurantiaca n.sp.: MAGRETTI 1884: 575 (description ♀ ♁, biology, Khor Gergabb, Sebderat), pl.1 (fig. 11).
Agenia nigroaurantiaca n.sp.: MAGRETTI 1885: 300 (Khor Gergabb), 321 (Sebderat), 353 (catalogue species collected by expedition).
Pseudagenia nigroaurantiaca MAGRETTI, 1884: KOHL 1897 (In: DALLA TORRE): 206 (taxonomy).
Pseudagenia nigroaurantiaca MAGRETTI, 1884: DALLA TORRE 1897: 206 (world catalogue, Eritrea part of Ethiopia).
Pseudagenia nigroaurantiaca MAGRETTI, 1884: ARNOLD 1934: 294 (key ♀), 295 (key ♀), 352 (taxonomy, description ♀, Khor Gergabb), 353 (figs 52, 52a).
Pseudagenia nigroaurantiaca MAGRETTI, 1884: JUNCO Y REYES 1951: 201 (world catalogue, Eritrea part of Ethiopia).
D i s t r i b u t i o n: Khor Gergabb, Sebderat.
Auplopus nigroaurantiacus is known from the Afrotropical (Central African Republic, Democratic Republic of the Congo, Eritrea, Ethiopia, South Africa, Zimbabwe) and Palaearctic (Saudi Arabia) regions.
description: Published as part of Madl, Michael, P, Cryptocheilus, D, Cyphononyx, H, Dichragenia & D, Hemipepsis, 2022, A catalogue of the Pompilidae (Hymenoptera, Vespoidea) of Eritrea, pp. 225-234 in Linzer biologische Beiträge 54 (1) on page 226, DOI: 10.5281/zenodo.7507390
Neokrisna stena Freytag 2012
Creators: name: Powell, Erin C.
name: Halbert, Susan E.
name: Deeter, Lily
name: Keller, Oliver
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Neokrisna
Neokrisna stena

description: Neokrisna stena Freytag, 2012
Neokrisna stena Freytag, 2012a: 7
Holotype: 1 ♁. DOMINICAN REPUBLIC:/ Pr. La Vega, La Cienaga / de Manabao, Park Hdqt./ 3–5-VII-99, 3000 ft. elev./ R. E.Woodruff, blacklight // [on red with black rectangle] HOLOTYPE/ [hw] Neokrisna / stena[/hw]/ P.H. Freytag [hw] 2008[/hw] // [upside down barcode label] FSCA 00070631.
Conservation status: Good condition; pinned; dissected abdomen in micro vial pinned under first label (Fig. 88).
description: Published as part of Powell, Erin C., Halbert, Susan E., Deeter, Lily & Keller, Oliver, 2023, An annotated and illustrated catalog of the primary type material of Hemiptera deposited in the Florida State Collection of Arthropods, pp. 1-107 in Zootaxa 5355 (1) on page 55, DOI: 10.11646/zootaxa.5355.1.1, http://zenodo.org/record/10022197
Theoretical Study of Terahertz Absorption Spectra and Neutron Inelastic Scattering in Frustrated Magnet $\text{Tb}_2\text{Ti}_2\text{O}_7$
Creators: name: Klekovkina, V. V.
name: Malkin, B. Z.
Publisher: name: arXiv
Year: 2025
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Within the framework of the single-particle approximation, the envelopes of the spectral lines of terahertz absorption and inelastic neutron scattering corresponding to magnetic dipole transitions between the sublevels of Tb$^{3+}$ ions in the Tb$_2$Ti$_2$O$_7$ crystal, split by the field of random deformations induced by point defects of the crystal lattice upon violation of the stoichiometric composition of the crystal, were calculated.
Osbornellus (Nereius) arcus Freytag 2008
Creators: name: Powell, Erin C.
name: Halbert, Susan E.
name: Deeter, Lily
name: Keller, Oliver
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Osbornellus
Osbornellus arcus

description: Osbornellus (Nereius) arcus Freytag, 2008
Osbornellus (Nereius) arcus Freytag, 2008: 139
Holotype: 1 ♁. DOM.REP.,LaVega,/ 18km.E.ElRio,Aug./ 10,1979,crest,cloud/ forest CW.O’Brien // [on red with black rectangle] Holotype/ [hw] Osbornellus / arcus[/hw]/ P.H. Freytag 2006 // [upside down barcode label] FSCA 00070584.
Conservation status: Good condition; point mounted; dissected abdomen in micro vial pinned under first label (Fig. 89).
description: Published as part of Powell, Erin C., Halbert, Susan E., Deeter, Lily & Keller, Oliver, 2023, An annotated and illustrated catalog of the primary type material of Hemiptera deposited in the Florida State Collection of Arthropods, pp. 1-107 in Zootaxa 5355 (1) on page 55, DOI: 10.11646/zootaxa.5355.1.1, http://zenodo.org/record/10022197
Auplopus rufocinctus
Creators: name: Madl, Michael
name: P, Cryptocheilus
name: D, Cyphononyx
name: H, Dichragenia
name: D, Hemipepsis
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Auplopus
Auplopus rufocinctus

description: Auplopus rufocinctus (SMITH, 1855)
Auplopus rufocinctus (SMITH, 1855): WAHIS 2000: 88 (taxonomy, Ghiunda = Ghinda)).
D i s t r i b u t i o n:Ghinda.
Auplopus rufocinctus, which is widely distributed in the Afrotropical region, is recorded from the Arabian Peninsula (Saudi Arabia, Yemen), but not from the African neighbour countries.
description: Published as part of Madl, Michael, P, Cryptocheilus, D, Cyphononyx, H, Dichragenia & D, Hemipepsis, 2022, A catalogue of the Pompilidae (Hymenoptera, Vespoidea) of Eritrea, pp. 225-234 in Linzer biologische Beiträge 54 (1) on page 227, DOI: 10.5281/zenodo.7507390
Predictive parameters for early detection of clinically relevant abdominal trauma in multiple-injury or polytraumatised patients
Creators: name: Fabig, Stefan
name: Weigert, Nadja
name: Migliorini, Filippo
name: Kleeff, Jörg H.
name: Hofmann, Gunther O.
name: Schenk, Philipp
name: Hilbert-Carius, Peter
name: Kobbe, Philipp
name: Mendel, Thomas
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Diagnosis of relevant organ injury after blunt abdominal injury (AI) in multiple-injury/polytraumatised patients is challenging. AI can be distinguished between injuries of parenchymatous organs (POI) of the upper abdomen (liver, spleen) and bowel and mesenteric injuries (BMI). Still, such injuries may be associated with delays in diagnosis and treatment. The present study aimed to verify laboratory parameters, imaging diagnostics, physical examination and related injuries to predict intraabdominal injuries. This retrospective, single-centre study includes data from multiple-injury/polytraumatised patients between 2005 and 2017. Two main groups were defined with relevant abdominal injury (AI+) and without abdominal injury (AI−). The AI+ group was divided into three subgroups: BMI+, BMI+/POI+, and POI+. Groups were compared in a univariate analysis for significant differences. Logistic regression analysis was used to determine predictors for AI+, BMI+ and POI+. 26.3% (271 of 1032) of the included patients had an abdominal injury. Subgroups were composed of 4.7% (49 of 1032) BMI+, 4.7% (48 of 1032) BMI+/POI+ and 16.8% (174 of 1032) POI+. Pathological abdominal signs had a sensitivity of 48.7% and a specificity of 92.4% for AI+. Transaminases were significantly higher in cases of AI+. Pathological computed tomography (CT) (free fluid, parenchymal damage, Bowel Injury Prediction Score (BIPS), CT Grade > 4) was summarised and had a sensitivity of 94.8%, a specificity of 98%, positive predictive value (PPV) of 94.5% and, negative predictive value (NPV) of 98.2% for AI+. The detected predictors for AI+ were pathological abdominal findings (odds ratio (OR) 3.93), pathological multi-slice computed tomography (MSCT) (OR 668.9), alanine (ALAT) ≥ 1.23 µmol/ls (OR 2.35) and associated long bone fractures (OR 3.82). Pathological abdominal signs, pathological MSCT and lactate (LAC) levels ≥ 1.94 mmol/l could be calculated as significant risk factors for BMI+. For POI+ pathological abdominal MSCT, ASAT ≥ 1.73 µmol/ls and concomitant thoracic injuries had significant relevance. The study presents reliable risk factors for abdominal injury and its sub-entities. The predictors can be explained by the anatomy of the trunk and existing studies. Elevated transaminases predicted abdominal injury (AI+) and, specifically, the POI+. The pathological MSCT was the most reliable predictive parameter. However, it was essential to include further relevant parameters.
Ontology-Enhanced Educational Annotation Activities
Creators: name: Gayoso-Cabada, Joaquí
name: Goicoechea-de-Jorge, María
name: Gómez-Albarrán, Mercedes
name: Sanz-Cabrerizo, Amelia
name: Sarasa-Cabezuelo, Antonio
name: Sierra, José-Luis
Publisher: name: arXiv
Year: 2025
Subjects: subject: Computation and Language (cs.CL)
subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: Information and communications technology and technology-enhanced learning have unquestionably transformed traditional teaching-learning processes and are positioned as key factors to promote quality education, one of the basic sustainable development goals of the 2030 agenda. Document annotation, which was traditionally carried out with pencil and paper and currently benefits from digital document annotation tools, is a representative example of this transformation. Using document annotation tools, students can enrich the documents with annotations that highlight the most relevant aspects of these documents. As the conceptual complexity of the learning domain increases, the annotation of the documents may require comprehensive domain knowledge and an expert analysis capability that students usually lack. Consequently, a proliferation of irrelevant, incorrect, and/or poorly decontextualized annotations may appear, while other relevant aspects are completely ignored by the students. The main hypothesis proposed by this paper is that the use of a guiding annotation ontology in the annotation activities is a keystone aspect to alleviate these shortcomings. Consequently, comprehension is improved, exhaustive content analysis is promoted, and meta-reflective thinking is developed. To test this hypothesis, we describe our own annotation tool, \@note, which fully implements this ontology-enhanced annotation paradigm, and we provide experimental evidence about how \@note can improve academic performance via a pilot study concerning critical literary annotation.
Guideline on positioning and early mobilisation in the critically ill by an expert panel
Creators: name: Schaller, Stefan
name: Scheffenbichler, Flora Alina Thaddäa
name: Bein, Thomas
name: Blobner, Manfred
name: Grunow, Julius
name: Hamsen, Uwe
name: Hermes, Carsten
name: Kaltwasser, Arnold
name: Nydahl, Peter
name: Reißhauer, Anett
name: Renzewitz, Leonie
name: Siemon, Karsten
name: Staudinger, Thomas
name: Ullrich, Roman
name: Weber-Carstens, Steffen
name: Wrigge, Hermann
name: Zergiebel, Dominik
name: Coldewey, Sina
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: A scientific panel was created consisting of 23 interdisciplinary and interprofessional experts in intensive care medicine, physiotherapy, nursing care, surgery, rehabilitative medicine, and pneumology delegated from scientific societies together with a patient representative and a delegate from the Association of the Scientific Medical Societies who advised methodological implementation. The guideline was created according to the German Association of the Scientific Medical Societies (AWMF), based on The Appraisal of Guidelines for Research and Evaluation (AGREE) II. The topics of (early) mobilisation, neuromuscular electrical stimulation, assist devices for mobilisation, and positioning, including prone positioning, were identified as areas to be addressed and assigned to specialist expert groups, taking conflicts of interest into account. The panel formulated PICO questions (addressing the population, intervention, comparison or control group as well as the resulting outcomes), conducted a systematic literature review with abstract screening and full-text analysis and created summary tables. This was followed by grading the evidence according to the Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence and a risk of bias assessment. The recommendations were finalized according to GRADE and voted using an online Delphi process followed by a final hybrid consensus conference. The German long version of the guideline was approved by the professional associations. For this English version an update of the systematic review was conducted until April 2024 and recommendation adapted based on new evidence in systematic reviews and randomized controlled trials. In total, 46 recommendations were developed and research gaps addressed.
Cryptocheilus octomaculatus
Creators: name: Madl, Michael
name: P, Cryptocheilus
name: D, Cyphononyx
name: H, Dichragenia
name: D, Hemipepsis
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Cryptocheilus
Cryptocheilus octomaculatus

description: Cryptocheilus octomaculatus (ROSSIUS, 1790)
* Salius bicolor (FABRICIUS, 1804): WALKER 1871: 17 (taxonomy, Rafla).
Salius bicolor R. (!): INNES BEY 1911: 110 (Rafla (Annesley Bay), catalogue Lord Collection).
D i s t r i b u t i o n:Rafla.
Cryptocheilus octomaculatus is known from the Palaearctic region. The identification should be checked.
description: Published as part of Madl, Michael, P, Cryptocheilus, D, Cyphononyx, H, Dichragenia & D, Hemipepsis, 2022, A catalogue of the Pompilidae (Hymenoptera, Vespoidea) of Eritrea, pp. 225-234 in Linzer biologische Beiträge 54 (1) on page 227, DOI: 10.5281/zenodo.7507390
Osbornellus (Nereius) brevitubus Freytag 2008
Creators: name: Powell, Erin C.
name: Halbert, Susan E.
name: Deeter, Lily
name: Keller, Oliver
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Osbornellus
Osbornellus brevitubus

description: Osbornellus (Nereius) brevitubus Freytag, 2008
Osbornellus (Nereius) brevitubus Freytag, 2008: 134
Holotype: 1 ♁. DOMINICAN REPUBLIC;/ Barahona, Filipinas, Larimar / Mine, 3300 ft, 12-IV-1997 // blacklight trap / R. E. Woodruff // [on red with black rectangle] Holotype/ [hw] Osbornellus (N.)/ brevitubus[/hw]/ P.H. Freytag 2006 // [upside down barcode label] FSCA 00070583.
Conservation status: Good condition; point mounted; dissected abdomen in micro vial pinned under second label (Fig. 90).
description: Published as part of Powell, Erin C., Halbert, Susan E., Deeter, Lily & Keller, Oliver, 2023, An annotated and illustrated catalog of the primary type material of Hemiptera deposited in the Florida State Collection of Arthropods, pp. 1-107 in Zootaxa 5355 (1) on page 55, DOI: 10.11646/zootaxa.5355.1.1, http://zenodo.org/record/10022197
The Holocode: Computation from Stacked Event Horizons
Creators: name: Padgett, Jason
Publisher: name: Zenodo
Year: 2025

description: The universe is an interference patterns of stacked and entanlged event horizons. The sum of their projectd histories where the action, in Feyman's sum over histories, is defined by the phase and frequency of quantum states on a lattice of Planck scale qubits.
MPEC 2024-X264 : 2024 XK14
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 XK14

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Osbornellus (Nereius) dicellus Freytag 2008
Creators: name: Powell, Erin C.
name: Halbert, Susan E.
name: Deeter, Lily
name: Keller, Oliver
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadellidae
Osbornellus
Osbornellus dicellus

description: Osbornellus (Nereius) dicellus Freytag, 2008
Osbornellus (Nereius) dicellus Freytag, 2008: 138
Holotype: 1 ♁. DOMINICAN REPUBLIC; La / Altagracia, [black spot] Nisibon, // [hw label] 3-V-1978, blacklight/ R. E.Woodruff / & G.B.Fairchild // [on red with black rectangle] Holotype/ [hw] Osbornellus (N.)/ dicellus[/hw]/ P.H. Freytag 2006 // [upside down barcode label] FSCA 00070587.
Conservation status: Good condition; point mounted; dissected abdomen in micro vial pinned under second label (Fig. 91).
description: Published as part of Powell, Erin C., Halbert, Susan E., Deeter, Lily & Keller, Oliver, 2023, An annotated and illustrated catalog of the primary type material of Hemiptera deposited in the Florida State Collection of Arthropods, pp. 1-107 in Zootaxa 5355 (1) on page 55, DOI: 10.11646/zootaxa.5355.1.1, http://zenodo.org/record/10022197