cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quantifying the validity and breakdown of the overdamped approximation in stochastic thermodynamics: Theory and experiment
Creators: name: Pan, Rui
name: Hoang, Thai M.
name: Fei, Zhaoyu
name: Qiu, Tian
name: Ahn, Jonghoon
name: Li, Tongcang
name: Quan, H. T.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Stochastic thermodynamics provides an important framework to explore small physical systems where thermal fluctuations are inevitable. In the studies of stochastic thermodynamics, some thermodynamic quantities, such as the trajectory work, associated with the complete Langevin equation (the Kramers equation) are often assumed to converge to those associated with the overdamped Langevin equation (the Smoluchowski equation) in the overdamped limit under the overdamped approximation. Nevertheless, a rigorous mathematical proof of the convergence of the work distributions to our knowledge has not been reported so far. Here we study the convergence of the work distributions explicitly. In the overdamped limit, we rigorously prove the convergence of the extended Fokker-Planck equations including work using a multiple timescale expansion approach. By taking the linearly dragged harmonic oscillator as an exactly solvable example, we analytically calculate the work distribution associated with the Kramers equation, and verify its convergence to that associated with the Smoluchowski equation in the overdamped limit. We quantify the accuracy of the overdamped approximation as a function of the damping coefficient. In addition, we experimentally demonstrate that the data of the work distribution of a levitated silica nanosphere agrees with the overdamped approximation in the overdamped limit, but deviates from the overdamped approximation in the low-damping case. Our work fills a gap between the stochastic thermodynamics based on the complete Langevin equation (the Kramers equation) and the overdamped Langevin equation (the Smoluchowski equation), and deepens our understanding of the overdamped approximation in stochastic thermodynamics.
description: 15 pages, 6 figures
A Method to Estimate the Primordial Power Spectrum from CMB Data
Creators: name: Bautista, Rafael
name: Torres, Sergio
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A precise determination of the primordial spectrum of matter density fluctuations at super-horizon scales is essential in understanding large scale structure in the universe. Attempts to constrain or obtain the primordial spectrum using data on cosmic microwave background (CMB) anisotropies has relied on statistical and correlation analyses that assume a power-law spectrum. We propose a method to derive $P(k)$ directly from the CMB angular power spectrum which does not presuppose the need to know anything about its functional form. The method consists of a direct inversion of the Sachs-Wolfe formula. Using this new analysis technique and COBE data we obtain an empirical $P(k)$ which 1) supports a power-law parameterization and 2) has an amplitude and spectral index consistent with previous analyses of the same data. We obtained for the spectral index, $n=1.52 \pm 0.4$ when the 2nd year COBE data is used and $n=1.22 \pm 0.3$ using the 4 year data set.
description: 6 pages, Latex(with aaas macros) + 3 (uuencoded) Postscript figures revised and accepted (ApJ) version with some corrections and inclusion of COBE 4yr data. New Fig 2 and 3 , PS files attached
Additional file 1 of Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype
Creators: name: Chernyakov, Dmitry
name: Groß, Alexander
name: Fischer, Annika
name: Bornkessel, Nicola
name: Schultheiss, Christoph
name: Gerloff, Dennis
name: Edemir, Bayram
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Word file S1. The detailed description of quality control, sequencing and bioinformatics of Novogene.
RX J2115-5840: confirmation of a new near-synchronous polar
Creators: name: Ramsay, Gavin
name: Buckley, David
name: Cropper, Mark
name: Harrop-Allin, M Kate
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Schwope et al (1997) suggested that the newly discovered Polar RX J2115-5840 is a near-synchronous system. We have obtained circular polarisation observations of RX J2115-5840 which show that the spin and orbital periods differ by 1.2%. We find the first direct evidence of `pole-switching' in a near-synchronous Polar. Further our data requires that the accretion flow must be directed onto the same magnetic field line at all spin-orbit beat phases implying that at some phases the flow must follow a path around the white dwarf before accreting.
description: To be published in Proc Annapolis workshop on magnetic CVs, held in July 1998
Distribution of Blue Galaxies in a Merging Cluster of Galaxies Abell 168
Creators: name: Tomita, A.
name: Nakamura, F. E.
name: Takata, T.
name: Nakanishi, K.
name: Takeuchi, T.
name: Ohta, K.
name: Yamada, T.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The fraction of star-forming galaxies in rich clusters of galaxies increases rapidly with the redshift. This is interpreted as the result of a rapid evolution of cluster galaxies, though its mechanism is not yet clear. One hypothesis is that if galaxies run into the dense intracluster medium (ICM) regions, starbursts can be induced due to compression of molecular clouds in the galaxies by a raised "external" ICM pressure. In a merging cluster, there would be dense ICM regions and some galaxies may experience a rapid increase of external pressure. Thus, if the mechanism works, starbursts would occur in such galaxies. Such a situation is considered to be realized in Coma cluster, and galaxies showing a recent starburst have a characteristic spatial distribution; they populate an elongated region between two sub-clusters. We examined the above hypothesis by measuring the spatial distribution of blue galaxies, regarded as star-forming galaxies in Abell~168 to check whether a case like Coma is realized in this recently merging cluster. However, we could not find an enhanced blue-galaxy distribution between two sub-clusters. We discuss the causes of our result, including possibilities of surviving the hypothesis.
description: uuencoded-gziped file made from 2 AAS LaTeX files. 35 pages including tables without figures. The paper has 10 figures. Access ftp://ftp.kusastro.kyoto-u.ac.jp/pub/atomita/preprint/pA168 To be appeared in AJ, Jan 1995 issue
Fermion scattering by a class of Bardeen black holes
Creators: name: Sporea, Ciprian A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper the scattering of fermions by a class of Bardeen black holes is investigated. After obtaining the scattering modes by solving the Dirac equation in this geometry, we use the partial wave method to derive an analytical expression for the phase shifts that enter into the definitions of partial amplitudes that define the scattering cross sections and the induced polarization. It is then showed that, like in the case of Schwarzschild and Reissner-Nordström, the phenomena of glory and spiral scattering are present.
description: v2: 11 pages (two-collumn), 7 figs., matches the published version in Chinese Physics C
Long-Term Stability of Planets in Binary Systems
Creators: name: Holman, Matthew
name: Wiegert, Paul
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: A simple question of celestial mechanics is investigated: in what regions of phase space near a binary system can planets persist for long times? The planets are taken to be test particles moving in the field of an eccentric binary system. A range of values of the binary eccentricity and mass ratio is studied, and both the case of planets orbiting close to one of the stars, and that of planets outside the binary orbiting the system's center of mass, are examined. From the results, empirical expressions are developed for both 1) the largest orbit around each of the stars, and 2) the smallest orbit around the binary system as a whole, in which test particles survive the length of the integration (10^4 binary periods). The empirical expressions developed, which are roughly linear in both the mass ratio mu and the binary eccentricity e, are determined for the range 0.0 <= e <= 0.7-0.8 and 0.1 <= mu <= 0.9 in both regions, and can be used to guide searches for planets in binary systems. After considering the case of a single low-mass planet in binary systems, the stability of a mutually-interacting system of planets orbiting one star of a binary system is examined, though in less detail.
description: 19 pages, 5 figures, 7 tables, accepted by the Astronomical Journal
Development of microfluidic platforms to construct giant unilamellar vesicles (GUVs) for the biophysical study of lipid membranes
Creators: name: Karamdad, Kaiser
Publisher: name: Imperial College London
Year: 2016

description: This thesis presents the design, development and application of several platforms through which to generate giant vesicles for biophysical and mechanical membrane studies. There has been a growing focus on manufacturing model membrane systems with improved throughput and structural properties in recent years. GUVs are a popular model membrane system for studying lipid membrane-associated phenomena due to their inherent similarity to biological cells. Traditional methods to construct vesicles offer little control over nuanced membrane properties such as asymmetry and patterning, which has paved the way for more refined techniques to be developed. This thesis details the development of a microfluidic platform technology that addresses this chasm in sophisticated GUV fabrication strategies. The technique presented offers control over key structural features such as vesicle size dispersity, internal content, membrane composition and asymmetry. Vesicles were investigated using contour detection and fluctuation analysis in order to quantify the bending rigidity in membranes constructed by microfluidics for the very first time. Furthermore, the emulsion phase transfer (EPT) method was refined for the construction of GUVs with phase separated membranes across three of compositions. This is the first investigation concerning domain formation in membranes constructed from emulsion precursors at a range of a compositions. The progress made in advancing platform technologies opens up various avenues through which to further explore biophysical phenomena such as a lipid flip-flop dynamics, as well as for the high-throughput generation of artificial cell systems, with potential relevance for therapeutic applications such as smart drug delivery.
title: ADCO, Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Cart. 143 (7 H 7), 153 fol, f. 0018r
Creators: name: de la Côte d'Or, Archives départementales
name: Projet CBMA
name: CG21/F.PETOT/2009
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0018r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Deuxième cartulaire ou Grand cartulaire de l'abbaye de Molesme, Archives départementales de la Côte-d'Or, Cart. 143 (7 H 7), 153 fol, f. 0018r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb137389344
description: Provenance: abbaye de Molesme
description: Provenance: http://www.wikidata.org/entity/Q334044
Additional fileÂ 1: of Diagnostic test accuracy of a novel smartphone application for the assessment of attention deficits in delirium in older hospitalised patients: a prospective cohort study protocol
Creators: name: Lisa-Marie Rutter
name: Nouzova, Eva
name: Stott, David
name: Weir, Christopher
name: Assi, Valentina
name: Barnett, Jennifer
name: Clarke, Caoimhe
name: Duncan, Nikki
name: Evans, Jonathan
name: Green, Samantha
name: Hendry, Kirsty
name: Meigan McGinlay
name: McKeever, Jenny
name: Middleton, Duncan
name: Parks, Stuart
name: Shaw, Robert
name: Tang, Elaine
name: Walsh, Tim
name: Weir, Alexander
name: Wilson, Elizabeth
name: Quasim, Tara
name: MacLullich, Alasdair
name: ZoĂŤ Tieges
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: This document presents instructions and scoring procedures for the DelApp arousal and attention assessments. Table S1. DelApp assessment and scoring procedure (i.e. arousal and attention assessment). Figure S1. Schematic display of DelApp arousal assessment and scoring. (PDF 124 kb)
Collisions of Main-Sequence Stars and the Formation of Blue Stragglers in Globular Clusters
Creators: name: Lombardi, J. C.
name: Rasio, F. A.
name: Shapiro, S. L.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the results of new SPH calculations of parabolic collisions between two main-sequence stars in a globular cluster. Such collisions are directly relevant to the formation of blue stragglers. In particular, we consider parent stars of mass $M/M_{TO}=0.2,0.5,0.75$, and $1$, where $M_{TO}$ is the cluster turnoff mass (typically about $0.8\,M_\odot$). Low-mass stars (with $M=0.2 M_{TO}$ or $0.5 M_{TO}$) are assumed to be fully convective and are therefore modeled as $n=1.5$ polytropes. Stars at the turnoff (with $M= M_{TO}$) are assumed to be mostly radiative and are modeled as $n=3$ polytropes. Intermediate-mass stars (with $M=0.75 M_{TO}$) are modeled as composite polytropes consisting of a radiative core with polytropic index $n=3$ and a convective envelope with $n=1.5$. We focus our study on the question of hydrodynamic mixing of helium and hydrogen, which plays a crucial role in determining the observable characteristics of blue stragglers. In all cases we find that there is negligible hydrodynamic mixing of helium into the outer envelope of the merger remnant. The amount of hydrogen mixed into the core of the merger depends strongly on the entropy profiles of the two colliding stars. In contrast to what has been done in previous studies, blue stragglers formed by direct stellar collisions should not necessarily be assumed to have initially homogeneous composition profiles.
description: uses AAS latex macros v3, 66 pages with tables and figures, submitted to ApJ, complete postscript also available at http://ensor.mit.edu/~rasio/papers
Changes in productivity across northern terrestrial ecosystems
Creators: name: Thomas, Rebecca Thursa
Publisher: name: Imperial College London
Year: 2018

description: It is well established that the terrestrial biosphere is currently a net carbon sink, driven by increases in productivity, but the mechanisms involved remain uncertain. Observations indicating large-scale increases in productivity across northern terrestrial ecosystems include aircraft data that show an increase in the amplitude of the seasonal cycle of CO2 (ASC) between 45-90N of 56±9.8% over the last 50 years (1958-61 - 2009-11), and satellite observed greening trends of 0.25-0.5%yr 1 between 30-90N since the 1980s. I analyse output from 13 terrestrial biosphere models taking part in the Multi-scale Synthesis and Terrestrial Model Intercomparison Project (MsTMIP) against these observations, which together provide a powerful benchmarks for models. I also validate a simple, data-driven model for photosynthesis, the P-model, which I use to further examine changes in productivity. New approaches are also required for analysing how model output relates to real-world observations. Thus, I additionally use the metric of ecosystem light-use e fficiency (eLUE), the ratio of ecosystem productivity to the light absorbed, to distinguish structural (i.e. greening) from physiological (i.e. rate of carbon fixation) vegetation changes in models on ecosystem scales. The MsTMIP models have good skill at representing observed greening trends and thus capture structural changes in vegetation, but they underestimate the observed increase in ASC, indicating that they underestimate changes in eLUE and productivity. The P-model, which is driven by observed greening, has a similar trend in productivity to the MsTMIP models and eLUE changes contribute only 34% to this trend. Although both the P-model and MsTMIP models show that productivity changes were driven primarily by CO2 fertilisation, this analysis suggests that models require better representation of CO2 fertilisation and other processes that can increase eLUE. Overall these results indicate that eLUE trends, larger than current models allow, are driving increases in productivity across high northern latitudes.
Anticipating cryptocurrency prices using machine learning
Creators: name: Alessandretti, Laura
name: ElBahrawy, Abeer
name: Aiello, Luca Maria
name: Baronchelli, Andrea
Publisher: name: arXiv
Year: 2018
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Machine Learning (cs.LG)
subject: General Finance (q-fin.GN)
subject: Statistical Finance (q-fin.ST)
subject: Trading and Market Microstructure (q-fin.TR)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Economics and business

description: Machine learning and AI-assisted trading have attracted growing interest for the past few years. Here, we use this approach to test the hypothesis that the inefficiency of the cryptocurrency market can be exploited to generate abnormal profits. We analyse daily data for $1,681$ cryptocurrencies for the period between Nov. 2015 and Apr. 2018. We show that simple trading strategies assisted by state-of-the-art machine learning algorithms outperform standard benchmarks. Our results show that nontrivial, but ultimately simple, algorithmic mechanisms can help anticipate the short-term evolution of the cryptocurrency market.
description: Complexity, 2018
Contribution of Bremsstrahlung Emission from Lyman-alpha Clouds to the Microwave Background Fluctuations
Creators: name: Loeb, Abraham
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: I calculate the contribution of Bremsstrahlung emission from Lyman-alpha absorption clouds to the brightness of the microwave sky. The calculation is based only on the assumption that the clouds below the Lyman-limit are in photoionization equilibrium with a UV background radiation, and avoids any uncertainty about the clumpiness of the gas. I predict a minimum fluctuation amplitude in the Rayleigh-Jeans regime of DeltaT/T = 10^{-5.5+-0.4}*J_21*(L/5cm)^2, which varies over characteristic angular scales of 1-100'', where L is the observed wavelength and J_21 is a weighted redshift average of the UV background intensity at the Lyman-limit in units of 10^{-21} erg cm^{-2} s^{-1} Hz^{-1} sr^{-1}. Detection of this signal can be used to map the intergalactic hydrogen distribution and to calibrate the UV background at high redshifts. Existing VLA observations constrain J_21<10^{1.3+-0.4}, unless some of the extended flat-spectrum sources which were detected are Lyman-alpha absorption systems.
description: 9 pages, uuencoded compressed Postscript, no figures
Mass transport and electrochemical properties of sodium bismuth titanate based electrolyte materials
Creators: name: Shih, Po-Chen (Duke)
Publisher: name: Imperial College London
Year: 2018

description: Oxide-ion conductors have drawn significant attention because of their crucial technical applications such as solid oxide fuel cells (SOFCs), oxygen separation membranes and sensors. Recently, sodium bismuth titanate (Na0.5Bi0.5TiO3, NBT) has been studied for its superior oxide-ion conductivity. In this thesis, the oxide-ion conductivity of acceptor-doped NBT is reported. A range of acceptor-type ions (K+, Li+, and Al3+) with varying doing levels are introduced into NBT, and their effects on material properties, including crystal structure, electrical conductivity, and oxygen transport properties, were investigated. Overall, low levels of acceptor dopants can be introduced on both cation sites of NBT through an ionic compensation mechanism that generates additional oxygen vacancies which improve oxide-ion conductivity to the levels of ~ 10-3 S cm-1 at 600 oC. Among the three acceptor dopants, a maximum enhancement of more than one order of magnitude was achieved by substituting Li on the A-site (7 x 10-3 S cm-1) or Al (3 x 10-3 S cm-1) on the B-site of NBT ceramics. The oxygen diffusion coefficients are in excellent agreement with the values derived from Electrochemical Impedance Spectroscopy data, confirming that the oxygen ions are the main charge carriers in the system. Finally, a degradation test was conducted under a variety of atmospheres and initial results show that Li- and Al-doped NBT materials were stable with a slight decay in conductivity. Compared with other well-known oxide-ion conductors, acceptor-doped NBT materials demonstrate superior ionic conductivity at temperatures above 600 oC and impressive durability under oxidizing atmospheres in the intermediate-temperature range. In short, the acceptor-doped NBT-based materials are excellent candidates for IT-SOFC applications.
Surrogate Outcomes and Transportability
Creators: name: Tikka, Santtu
name: Karvanen, Juha
Publisher: name: arXiv
Year: 2018
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Identification of causal effects is one of the most fundamental tasks of causal inference. We consider an identifiability problem where some experimental and observational data are available but neither data alone is sufficient for the identification of the causal effect of interest. Instead of the outcome of interest, surrogate outcomes are measured in the experiments. This problem is a generalization of identifiability using surrogate experiments and we label it as surrogate outcome identifiability. We show that the concept of transportability provides a sufficient criteria for determining surrogate outcome identifiability for a large class of queries.
description: This is the version published in the International Journal of Approximate Reasoning
Three years of Galileo dust data: II. 1993 to 1995
Creators: name: Krüger, H.
name: Grün, E.
name: Hamilton, D. P.
name: Baguhl, M.
name: Dermott, S.
name: Fechtig, H.
name: Gustafson, B. A.
name: Hanner, M. S.
name: Horányi, M.
name: Kissel, J.
name: Lindblad, B. A.
name: Linkert, D.
name: Linkert, G.
name: Mann, I.
name: McDonnell, J. A. M.
name: Morfill, G. E.
name: Polanskey, C.
name: Riemann, R.
name: Schwehm, G.
name: Srama, R.
name: Zook, H. A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Between Jan 1993 and Dec 1995 the Galileo spacecraft traversed interplanetary space between Earth and Jupiter and arrived at Jupiter on 7 Dec 1995. The dust instrument onboard was operating during most of the time. A relatively constant impact rate of interplanetary and interstellar (big) particles of 0.4 impacts per day was detected over the whole three-year time span. In the outer solar system (outside about 2.6 AU) they are mostly of interstellar origin, whereas in the inner solar system they are mostly interplanetary particles. Within about 1.7 AU from Jupiter intense streams of small dust particles were detected with impact rates of up to 20,000 per day whose impact directions are compatible with a Jovian origin. Two different populations of dust particles were detected in the Jovian magnetosphere: small stream particles during Galileo's approach to the planet and big particles concentrated closer to Jupiter between the Galilean satellites. There is strong evidence that the dust stream particles are orders of magnitude smaller in mass and faster than the instrument's calibration, whereas the calibration is valid for the big particles. Because the data transmission rate was very low, the complete data set for only a small fraction (2525) of all detected particles could be transmitted to Earth; the other particles were only counted. Together with the 358 particles published earlier, information about 2883 particles detected by the dust instrument during Galileo's six years' journey to Jupiter is now available.
description: Accepted for Planetary and Space Science, 37 pages, 5 tables, 13 figures
Phase-space geometric Sagnac interferometer for rotation sensing
Creators: name: Che, Yanming
name: Yao, Fei
name: Liang, Hongbin
name: Li, Guolong
name: Wang, Xiaoguang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum information processing with geometric features of quantum states may provide promising noise-resilient schemes for quantum metrology. In this work, we theoretically explore phase-space geometric Sagnac interferometers with trapped atomic clocks for rotation sensing, which could be intrinsically robust to certain decoherence noises and reach high precision. With the wave guide provided by sweeping ring-traps, we give criteria under which the well-known Sagnac phase is a pure or unconventional geometric phase with respect to the phase space. Furthermore, corresponding schemes for geometric Sagnac interferometers with designed sweeping angular velocity and interrogation time are presented, and the experimental feasibility is also discussed. Such geometric Sagnac interferometers are capable of saturating the ultimate precision limit given by the quantum Cramér-Rao bound.
description: 9 pages, 2 figures
Non-linear system identification in structural dynamics: advances in characterisation of non-linearities and non-linear modal analysis
Creators: name: Ondra, Václav
Publisher: name: Imperial College London
Year: 2017

description: Many new methods for theoretical modelling, numerical analysis and experimental testing have been developed in non-linear dynamics in recent years. Although the computational power has greatly improved our ability to predict non-linear behaviour, non-linear system identification, a central topic of this thesis, still plays a key role in obtaining and quantifying structural models from experimental data. The first part of the thesis is motivated by the industrial needs for fast and reliable detection and characterisation of structural non-linearities. For this purpose a method based on the Hilbert transform in the frequency domain is proposed. The method detects and characterises structural non-linearities from a single frequency response function and does not require a priori knowledge of the system. The second part of the thesis is driven by current research trends and advances in non-linear modal analysis and adaptive time series processing using the Hilbert-Huang transform. Firstly, the alternatives of the Hilbert transform, which is commonly used in structural dynamics for the estimation of the instantaneous frequency and amplitude despite suffering from a number of numerical issues, are compared to assess their potential for non-linear system identification. Then, a possible relation between the Hilbert-Huang transform and complex non-linear modes of mechanical systems is investigated. Based on this relation, an approach to experimental non-linear modal analysis is proposed. Since this approach integrates the Hilbert-Huang transform and non-linear modes, it allows not only to detect and characterise structural non-linearities in a non-parametric manner, but also to quantify the parameters of a selected model using extracted non-linear modes. Lastly, a new method for the identification of systems with asymmetric non-linear restoring forces is proposed. The application of all proposed methods is demonstrated on simulated and experimental data.
Additional file 4: of Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple displacement amplification and exome sequencing
Creators: name: Simonsen, Anita
name: Hansen, Marcus
name: Kjeldsen, Eigil
name: Møller, Peter
name: Hindkjær, Johnny
name: Hokland, Peter
name: Aggerholm, Anni
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Figure S3. Kernel density estimates of allele frequencies enables the detection of trisomy down to two cells. Variant alleles are normally a bimodal distribution, whereas trisomies display a trimodal distribution as shown for chromosome 8. The Gaussian function was used as kernel and bandwidth selection was based on Silverman’s rule ((4σ^5/3n)^1/5). The functions have been scaled to same maximum (at VAF = 1) for relative comparison. As a result, the Y-axis is unitless. (PDF 117 kb)
Additional file 6 of Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype
Creators: name: Chernyakov, Dmitry
name: Groß, Alexander
name: Fischer, Annika
name: Bornkessel, Nicola
name: Schultheiss, Christoph
name: Gerloff, Dennis
name: Edemir, Bayram
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6: Figure S1. (A) Schematic representation of domain organization in RANBP3L and RANBP3 (AS sequence in Table S1). (B) Median gene expression of RANBP3 and RANBP3L in a bodymap from the gene expression profiling interactive analysis tool (GEPIA2) [33]. (C) Schematic representation of IMCD isolation and culturing from murine kidneys for next-generation sequencing (NGS). (D-E) Analysis of NFAT5 intensity in mpKCCD immunofluorescence images (D) and in IMCD cell immunofluorescence images (E) shown in Fig. 2A. Scale bar 100 μm. (F-G) The NFAT5 fluorescence intensities of cells were plotted on a line graph. Lines correspond to the relative fluorescence of cells marked with a white arrow. F corresponds to signal intensity in mpkCCD cell while G corresponds to signal intensity of IMCD cells. (H) TIDE analysis of N1 and N3 single clones reveal INDELs in the Nfat5 target sites [26]. (I) Selected distribution of RNA-Seq reads across the Nfat5 gene for control and 4-OH-TM treated cells shows loss of exon 4. (J) Screen capture of human RANBP3L promotor region from the ECR Browser website with evolutionary conserved regions (ECR) in the genomes of rat, mouse, canis, macaca and pan. The lines in pink (arrows ahead) show ECR between human and the indicated mammals [28]. (K) 800 bp region uptream from RANBP3L start site is conserved in the indicated mammals and contains one conserved NFAT5 consensus sequence (NNTTTCCA is indicated in yellow) and one non-conserved (nucleotides are indicated in red). (L) Relative promotor activity of all Ranbp3l promotor constructs normalized to the isoosmolar control (n = 4, each with duplicates). n.s. > 0.05, *, p
The UK Neonatal Collaborative Necrotising Enterocolitis (NEC) study: testing the utility of operational clinical data to conduct population surveillance, develop an evidence-based case-definition and identify risk factors associated with NEC
Creators: name: Battersby, Cheryl Wing
Publisher: name: Imperial College London
Year: 2016

description: Background: Necrotising enterocolitis (NEC) is growing in global relevance. Aetiology and pathophysiology are uncertain; non-invasive diagnostic tests and case-definition lacking; population incidence data scant, and evidence to inform preventive feeding strategies are inadequate. The National Neonatal Research Database (NNRD) comprises data from infants admitted to neonatal units in England and offers opportunities to facilitate population studies. Methods: I performed a systematic review of global NEC incidence; secured the participation of all English neonatal units in a prospective two-year study employing the NNRD as the source of data; quantified the burden of severe NEC (confirmed at laparotomy and/or leading to death); investigated the impact of early maternal breast milk (MBM), and avoidance of bovine products (formula/fortifier) on NEC, and developed a case-definition for NEC suitable for surveillance and research. Statistical methods included multivariate logistic regression, funnel plot and propensity analysis. Results: 118,073 infants (14,678 <32 weeks (w) gestational age (GA)) were admitted to 163 English neonatal units (23 networks) in 2012-2013; 531 (462; 3.15% of infants <32w GA) developed severe NEC; 20% died without a laparotomy; a third who received a laparotomy died. Among infants <32w there was no strong evidence of variation in relation to the adjusted national incidence of 3.13% (95%CI 2.85, 3.42) despite variation in feeding practices. Early vs. late or no MBM (within 7 days) resulted in an Absolute Risk Difference (ARD) of -0.88% (95% CI -1.15, -0.61), Relative Risk (RR) 0.69 (95% CI 0.60, 0.78); equivalent figures for no vs. any bovine products within 14 postnatal days, were ARD -0.65% (95% CI -1.01, 0.29), RR 0.61 (95% CI 0.39, 0.83). The ordinal NEC score allocated three points to pneumatosis, two to blood in stools and one to abdominal tenderness; abdominal discolouration; the composite of increased and/or bilious aspirates AND abdominal distension; one or more of pneumoperitoneum, fixed loop and portal venous gas. Infants with a score of ≥2 (<30 w); ≥3 (30 to <37 w); ≥4 (≥37w GA) were considered to have NEC. Conclusions: This thesis provides, for the first time, population incidence of severe NEC in England. The proposed NEC score and GA-specific case-definition offer opportunity to strengthen research efforts. Commencing MBM early and avoiding bovine products may reduce NEC but effect sizes appear small. The lack of network variation in severe NEC despite differences in feeding practices highlights the need to address ongoing uncertainties.
Dependence of the Fundamental Plane Scatter on Galaxy Age
Creators: name: Forbes, Duncan
name: Ponman, Trevor
name: Brown, Richard
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The fundamental plane (FP) has an intrinsic scatter that can not be explained purely by observational errors. Using recently available age estimates for nearby early type galaxies, we show that a galaxy's position relative to the FP depends on its age. In particular, the mean FP corresponds to ellipticals with an age of ~10 Gyr. Younger galaxies are systematically brighter with higher surface brightness relative to the mean relation. Old ellipticals form an `upper envelope' to the FP. For our sample of mostly non-cluster galaxies, age can account for almost half of the scatter in the B band FP. Distance determinations based on the FP may have a systematic bias, if the mean age of the sample varies with redshift. We also show that fundamental plane residuals, B-V colors and Mg_2 line strength are consistent with an ageing central burst superposed on an old stellar population. This reinforces the view that these age estimates are tracing the last major episode of star formation induced by a gaseous merger event. We briefly discuss the empirical `evolutionary tracks' of merger-remnants and young ellipticals in terms of their key observational parameters.
description: 14 pages, Latex, 2 figures, accepted by ApJ Letters
Alcedo todus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Coraciiformes
Alcedinidae
Alcedo
Alcedo todus

description: Alcedo todus [spec. nov.]
A. brachyura viridis, gula sanguinea, abdomine albo.
Rubecula viridis elegantissima. Edw. av. 121. t. 121. f. 1. Sloan. jam. 2. p. 306. t. 263. f. 1. Raj. av. 187.
Todus viridis, pectore rubro, rostro recto. Brown. jam. 476.
Habitat in America.
Genus dubium & quasi medium inter Alcedinem & Trochilum.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 116, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Two-Dimensional Yang-Mills Theory on Surfaces With Corners in Batalin-Vilkovisky Formalism
Creators: name: Iraso, Riccardo
name: Mnev, Pavel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we recover the non-perturbative partition function of 2D~Yang-Mills theory from the perturbative path integral. To achieve this goal, we study the perturbative path integral quantization for 2D~Yang-Mills theory on surfaces with boundaries and corners in the Batalin-Vilkovisky formalism (or, more precisely, in its adaptation to the setting with boundaries, compatible with gluing and cutting -- the BV-BFV formalism). We prove that cutting a surface (e.g. a closed one) into simple enough pieces -- building blocks -- and choosing a convenient gauge-fixing on the pieces, and assembling back the partition function on the surface, one recovers the known non-perturbative answers for 2D~Yang-Mills theory.
description: 70 pages; small expository changes, citations added
Additional file 3: of Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple displacement amplification and exome sequencing
Creators: name: Simonsen, Anita
name: Hansen, Marcus
name: Kjeldsen, Eigil
name: MĂ¸Ller, Peter
name: HindkjĂŚr, Johnny
name: Hokland, Peter
name: Aggerholm, Anni
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 60506 Virology

description: Figure S2. Variability of allele depths. The known driver mutations are shown along with another focus variant MET T1010I of unknown relevance. (PDF 34 kb)
Long and Short GRB
Creators: name: Katz, J. I.
name: Canel, L. M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report evidence from the 3B Catalogue that short (T_90 < 10 s) and long (T_90 > 10 s) GRB represent different populations and processes: Their spectral behavior is qualitatively different, with short bursts harder in the BATSE range, but chiefly long bursts detected at higher photon energies; \langle V/V_max \rangle = 0.385 \pm 0.019 for short GRB but \langle V/V_max \rangle = 0.282 \pm 0.014 for long GRB, differing by 0.103 \pm 0.024. Long GRB may be the consequence of accretion-induced collapse, but this mechanism fails for short GRB, for which we suggest colliding neutron stars.
description: 5 pp., latex, no figures, revised to work around bug in latex compiler
Rossby Wave Instability of Keplerian Accretion Disks
Creators: name: Lovelace, R. V. E.
name: Li, H.
name: Colgate, S. A.
name: Nelson, A. F.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We find a linear instability of non-axisymmetric Rossby waves in a thin non-magnetized Keplerian disk when there is a local maximum in the radial profile of a key function ${\cal L}(r) \equiv {\cal F}(r) S^{2/Γ}(r)$, where ${\cal F}^{-1} = \hat {\bf z}\cdot ({\bf \nabla}\times {\bf v}) /Σ$ is the potential vorticity, $S = P/Σ^Γ$ is the entropy, $Σ$ is the surface mass density, $P$ is the vertically integrated pressure, and $Γ$ is the adiabatic index. We consider in detail the special case where there is a local maximum in the disk entropy profile $S(r)$. This maximum acts to trap the waves in its vicinity if its height to width ratio ${\rm max}(S)/Δr$ is larger than a threshold value. The pressure gradient derived from this entropy variation provides the restoring force for the wave growth. We show that the trapped waves act to transport angular momentum outward. A plausible way to produce an entropy variation is when an accretion disk is starting from negligible mass and temperature, therefore negligible entropy. As mass accumulates by either tidal torquing, magnetic torquing, or Roche-lobe overflow, confinement of heat will lead to an entropy maximum at the outer boundary of the disk. Possible nonlinear developments from this instability include the formation of Rossby vortices and the formation of spiral shocks. What remains to be determined from hydrodynamic simulations is whether or not Rossby wave packets (or vortices) ``hold together'' as they propagate radially inward.
description: Accepted to ApJ (Part 1), aaspp4 format, 15 pages, 3 figures
Additional file 2: of Systematic evaluation of signal-to-noise ratio in variant detection from single cell genome multiple displacement amplification and exome sequencing
Creators: name: Simonsen, Anita
name: Hansen, Marcus
name: Kjeldsen, Eigil
name: MĂ¸Ller, Peter
name: HindkjĂŚr, Johnny
name: Hokland, Peter
name: Aggerholm, Anni
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 60506 Virology
subject: Computational Biology

description: Figure S1. The number of GATK-passed variants increase as cell input decreases. (PDF 39 kb)
XENON1T Takes a Razor to a Dark $E_6$-Inspired Model
Creators: name: Camargo, Daniel A.
name: Mambrini, Yann
name: Queiroz, Farinaldo S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Motivated by the recent result of XENON1T collaboration with full exposure, 279 life days, that sets the most stringent limit on the spin-independent dark matter-nucleon scattering cross section we discuss a dark $E_6$-inspired model that features the presence of a $U(1)_{d-u}$ gauge symmetry. The dark matter candidate is a Dirac fermion that interacts with Standard Model fermions via a massive Z' that preserves the quantum number assignments of this symmetry. We compute the spin-independent scattering cross section off xenon nucleus and compare with the XENON1T limit; find the LHC bound on the Z' mass as well as the projection sensitivity of high-energy and luminosity LHC; and derive the Fermi-LAT bounds on the dark matter annihilation cross section based on the observation of gamma-rays in the direction of Dwarf Spheroidal galaxies. We exploit the complementarity between these datasets to conclude that the new bound from XENON1T severely constrain the model, which combined with the LHC upgrade sensitivity rules out this WIMP realization setup below 5 TeV.
description: 7 pages, 3 figures
Open Inflation
Creators: name: Garcia-Bellido, Juan
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Open Inflation has recently been suggested as a possible way out of the age crisis caused by observations of a large rate of expansion of the universe, in conflict with the existence of very old globular clusters. It proposes that our local patch of the universe originated in a quantum tunneling event, with the formation of a single bubble within which our universe inflated to almost flatness. I review the different models proposed together with their predictions for the amplitude of temperature anisotropies in the cosmic microwave background.
description: RevTex, 3 pages, Contribution to TAUP '95 Conference Proceedings, Toledo, Sept 1995. also available on WWW at http://star.maps.susx.ac.uk/index.html
Alcedo smyrnensis Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Coraciiformes
Alcedinidae
Alcedo
Alcedo smyrnensis

description: Alcedo smyrnensis [spec. nov.]
A. macroura ferruginea, alis cauda dorsoque viridibus. Alcedo smyrnensis. Alb. av. 3. p. 26. t. 27.
Ispida major africana. Edw. av. 8. t. 8.
Habitat in Africa & Asia.
Confer. Alcedo major benghalensis. Alb. av. 3. p. 271. 28.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 116, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Improved limits on gamma ray burst repetition
Creators: name: Tegmark, Max
name: Hartmann, Dieter
name: Briggs, Michael
name: Hakkila, Jon
name: Meegan, Charles
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We tighten previous upper limits on gamma ray burst repetition by analyzing the angular power spectrum of the BATSE 3B catalog of 1122 bursts. At 95% confidence, we find that no more than 2% of all observed bursts can be labeled as repeaters, even if no sources are observed to repeat more than once. If a fraction f of all observed bursts can be labeled as repeaters that are observed to burst v times each, then all models with (v-1)f>0.05 are ruled out at 99% confidence, as compared to the best previous 99% limit (v-1)f>0.27. At 95% confidence, our new limit is (v-1)f>0.02. Thus even a cluster of 6 events from a single source would have caused excess power above that present in the 3B catalog. We conclude that the current BATSE data are consistent with no repetition of classical gamma ray bursts, and that any repeater model is severely constrained by the near perfect isotropy of their angular distribution.
description: 18 pages, with 2 figures included. Postscript. Submitted to ApJL. Latest version at http://astro.berkeley.edu/~max/repeaters.html (faster from the US), from http://www.mpa-garching.mpg.de/~max/repeaters.html (faster from Europe) or from max@mppmu.mpg.de