cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Immunoconiugati contenenti tossine vegetali o siRNA per la deplezione selettiva di cellule leucemiche.
Preparazione, citotossicità e studi di mutagenesi sito-specifica.
Immunoconjugates containing plant toxins or siRNAs for selective depletion of leukemic cells.
Preparation, cytotoxicity and site-directed mutagenesis studies.
Creators: name: Mancuso, Rossella <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: MED/04 Patologia generale

description: CD33 is a myeloid cell surface marker absent on normal hematopoietic stem cells and normal tissues but present on leukemic blasts in 90% of adult and paediatric acute myeloid leukaemia (AML) cases. By virtue of its expression pattern and its ability to be rapidly internalized after antibody binding, CD33 has become an attractive target for new immunotherapeutic approaches to treat AML.
In this study two immunoconjugates were constructed to contain a humanised single-chain fragment variable antibody (scFv) against CD33 in order to create new antibody-derived therapeutics for AML. 
The first immunoconjugate was developed to provide targeted delivery of siRNAs as death effectors into leukemic cells. To this purpose, a CD33-specific scFv, modified to include a Cys residue at its C-terminal end (scFvCD33-Cys), was coupled through a disulphide bridge to a nona-d-arginine (9R) peptide carrying a free Cys to the N-terminal. The scFvCD33-9R was able to completely bind siRNAs at a protein to nucleic acid ratio of about 10:1, as confirmed by electrophoretic gel mobility-shift assay. The conjugate was unable to efficiently transduce cytotoxic siRNA (siTox) into the human myeloid cell line U937. We observed slight reductions in cell viability, with a reduction of 25% in comparison to the control group only at high concentration of siTox (300 nM).
The second immunoconjugate was constructed by coupling the scFvCD33-Cys to the type 1 ribosome inactivating protein Dianthin 30 (DIA30) through a chemical linking
The resulting immunotoxin scFvCD33-DIA30 caused the rapid arrest of protein synthesis, inducing apoptosis and leading ultimately to cell death. 
In vitro dose-dependent cytotoxicity assays demonstrated that scFvCD33-DIA30 was specifically toxic to CD33-positive cell U937. The concentration needed to reach 50 % of maximum killing efficiency (EC50) was approximately 0.3 nM. The pronounced antigen-restricted cytotoxicity of this novel agent makes it a candidate for further evaluation of its therapeutic potential.
A Novel Approach to Classifying Breast Cancer Histopathology Biopsy Images Using Bilateral Knowledge Distillation and Label Smoothing Regularization
Creators: name: B, Prasanalakshmi
Publisher: name: figshare
Year: 2021
Subjects: subject: 111202 Cancer Diagnosis
subject: FOS: Clinical medicine

description: Breast cancer is the most common invasive cancer in women and the second main cause of cancer death in females, which can be classified benign or malignant. Research and prevention on breast cancer have attracted more concern of researchers in recent years. On the other hand, the development of data mining methods provides an effective way to extract more useful information from complex databases, and some prediction, classification, and clustering can be made according to the extracted information. The generic notion of knowledge distillation is that a network of higher capacity acts as a teacher and a network of lower capacity acts as a student. There are different pipelines of knowledge distillation known. However, previous work on knowledge distillation using label smoothing regularization produces experiments and results that break this general notion and prove that knowledge distillation also works when a student model distils a teacher model, i.e., reverse knowledge distillation. Not only this, but it is also proved that a poorly trained teacher model trains a student model to reach equivalent results. Building on the ideas from those works, we propose a novel bilateral knowledge distillation regime that enables multiple interactions between teacher and student models, i.e., teaching and distilling each other, eventually improving each other’s performance and evaluating our results on BACH histopathology image dataset on breast cancer. The pretrained ResNeXt29 and MobileNetV2 models which are already tested on ImageNet dataset are used for “transfer learning” in our dataset, and we obtain a final accuracy of more than 96% using this novel approach of bilateral KD.
Abundances of the elements in the solar system
Creators: name: Lodders, K.
name: Palme, H.
name: Gail, H. -P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: A review of the abundances and condensation temperatures of the elements and their nuclides in the solar nebula and in chondritic meteorites. Abundances of the elements in some neighboring stars are also discussed.
description: 42 pages, 11 tables, 8 figures, chapter, In Landolt- B\"ornstein, New Series, Vol. VI/4B, Chap. 4.4, J.E. Tr\"umper (ed.), Berlin, Heidelberg, New York: Springer-Verlag, p. 560-630
O impacte dos ajustamentos orçamentais na procura internacional de turismo: o caso de Portugal
Creators: name: Pêgo, Pedro Mariano
name: Costa, Rui Augusto Da
name: Viegas, Miguel
Publisher: name: Revista Turismo & Desenvolvimento
Year: 2014

description: Em períodos onde ocorrem grandes ajustamentos orçamentais na economia de um país, a despesa e o investimento público diminuem em consequência desse processo de ajustamento. Frequentemente assiste-se a um aumento generalizado de impostos de forma a gerar mais receita pública, e, pelo lado da despesa, a um corte ‘cego’ nas despesas do Estado de forma a reduzir os gastos públicos. Ora uma maior carga fiscal tem reflexos, diretos ou indiretos, nos rendimentos do trabalho que, por sua vez, levam a uma diminuição do poder de compra da população e consequentemente à diminuição da procura interna. Este tipo de políticas orçamentais, no curto prazo, conduz à contração da economia de um país e a retoma económica depende fortemente do setor da exportação de bens e serviços onde se encontra o turismo. Entre 1970 e 2012 Portugal viu-se forçado a fazer três fortes ajustamentos orçamentais devido a desequilíbrios externos. O presente trabalho pretende inferir se a procura turística externa em Portugal evoluiu a contraciclo funcionando desta forma como um estabilizador da economia, ou se pelo contrário, apresenta uma evolução cíclica a par da conjuntura económica. Utilizando-se um modelo autorregressivo de desfasagens distribuídas para o período 1970-2012, o resultado das estimações sugere que o setor turístico durante as fases de ajustamento orçamental nunca serviu de estabilizador da economia.
description: Revista Turismo & Desenvolvimento, vol. 4 n.º 21/22 (2014)
The business structure and the employment characteristics of the restaurants industry: the dominance of small familyrun businesses: evidences from the city of Aveiro, Portugal
Creators: name: Simão, Pedro
name: Breda, Zélia
Publisher: name: Journal of Tourism & Development
Year: 2014

description: Nowadays tourism is a very important sector in most economies, being its relevance also recognized in the academia. Many researchers have been studying this sector in several different perspectives, but there is not much evidence on the restaurants industry and on its characteristics. Therefore, this study aims to present the main specificities associated with the restaurant business in the city of Aveiro (Portugal), as well as managers’ and employees’ employment characteristics. For that purpose, a questionnaire survey was conducted. Results show that both managers and employees present low educational qualifications, work long hours, and have low salaries. As for businesses, the restaurants industry is mostly characterised by the dominance of SMEs, which in the current economic situation, are facing a harsh time and need to be creative to be able to surpass a number of barriers in order to become more competitive. Managers are required to carefully analyse the most important aspects of their businesses so that they can stay competitive in the long run.
description: Journal of Tourism & Development, vol. 4 n.º 21/22 (2014)
Orientação empreendedora no contexto internacional: um estudo de caso da Vinícola Panceri
Creators: name: Tonial, Graciele
name: Rosseto, Carlos Ricardo
Publisher: name: Revista Turismo & Desenvolvimento
Year: 2014

description: O objetivo deste estudo é analisar a orientação empreendedora internacional (OEI) em uma empresa vinícola internacionalizada do sul do Brasil. Adotou-se a abordagem qualitativa, por meio de um estudo exploratório e descritivo. Utilizou-se o método estudo de caso único, os dados foram coletados por pesquisa documental e de campo sendo aplicadas entrevistas semiestruturadas. Nos resultados identificaram-se comportamentos decorrentes da prática organizacional da empresa que caracterizam a OEI, com maior ocorrência nas dimensões ‘inovatividade internacional’ e ‘proatividade internacional’. Na dimensão ‘assunção ao risco internacional’ ficou evidenciado algumas disparidades, pois alguns elementos se apresentam com maior ocorrência que outros. Nas dimensões ‘agressividade competitiva’ e ‘autonomia internacional’, os elementos são identificados em menor ocorrência, corroborando com o conceito de multidimensionalidade na OEI.
description: Revista Turismo & Desenvolvimento, vol. 4 n.º 21/22 (2014)
Production of eta and 3pi mesons in the pd->3HeX reaction at 1360 and 1450 MeV
Creators: name: Schoenning, K.
name: Bargholtz, Chr.
name: Bashkanov, M.
name: Berlowski, M.
name: Bogoslawsky, D.
name: Calen, H.
name: Clement, H.
name: Demiroers, L.
name: Ekstroem, C.
name: Fransson, K.
name: Geren, L.
name: Gustafsson, L.
name: Hoeistad, B.
name: Ivanov, G.
name: Jacewicz, M.
name: Jiganov, E.
name: Johansson, T.
name: Keleta, S.
name: Khakimova, O.
name: Kren, F.
name: Kullander, S.
name: Kupsc, A.
name: Kuzmin, A.
name: Lindberg, K.
name: Marciniewski, P.
name: Morosov, B.
name: Oelert, W.
name: Pauly, C.
name: Petren, H.
name: Petukhov, Y.
name: Povtorejko, A.
name: Scobel, W.
name: Shafigullin, R.
name: Shwartz, B.
name: Skorodko, T.
name: Sopov, V.
name: Stepaniak, J.
name: tegner, P. -E.
name: Engblom, P. Thoerngren
name: Tikhomirov, V.
name: Turowiecki, A.
name: Wagner, G. J.
name: Wolke, M.
name: Zabierowski, J.
name: Zartova, I.
name: Zlomanczuk, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The cross sections of the pd -> 3He eta, pd -> 3He pi0 pi0 pi0 and pd -> 3He pi+ pi- pi0 reactions have been measured at beam kinetic energies T_p= 1360 MeV and T_p= 1450 MeV using the CELSIUS/WASA detector setup. At both energies, the differential cross section dsigma/dOmega of the eta meson in the pd -> 3He eta reaction shows a strong forward-backward asymmetry in the CMS. The ratio between the pd -> 3He pi+ pi- pi0 and the pd -> 3He pi0 pi0 pi0 cross sections has been analysed in terms of isospin amplitudes. The reconstructed invariant mass distributions of the pi-pi, 3He-pi and 3He-2pi systems provide hints on the role of nucleon resonances in the 3pi production process.
description: Shorter version accepted to EPJA 10 pages 14 figures
Turismo e desenvolvimento económico em territórios rurais: uma revisão da literatura
Creators: name: Milheiro, Eva
name: Eusébio, Celeste
name: Kastenholz, Elisabeth
Publisher: name: Revista Turismo & Desenvolvimento
Year: 2014

description: O turismo pode ser encarado como uma atividade suscetível de contribuir para o desenvolvimento das áreas rurais. Neste contexto, o presente artigo pretende analisar os estudos científicos existentes sobre os impactes que o turismo pode ter no desenvolvimento das áreas rurais. Com o intuito de alcançar este objetivo, foram realizadas pesquisas numa base de dados científica, a SCOPUS, tendo-se obtido um total de 123 artigos publicados na última década que, após filtrados, resultaram em vinte artigos que foram considerados relevantes para este estudo. Da análise destes artigos é possível concluir que: (i) os autores são relativamente consensuais quanto à importância do turismo para o desenvolvimento das áreas rurais; (ii) emergem essencialmente duas dimensões de análise nos artigos analisados, nomeadamente os impactes do turismo e as perceções e atitudes dos residentes face ao turismo nas áreas rurais; (iii) verifica-se uma predominância de utilização de metodologias quantitativas nos estudos empíricos desenvolvidos, principalmente nos que concernem à análise das perceções dos residentes face aos impactes do turismo, sendo o questionário o método de recolha de dados mais utilizado. O artigo termina com algumas reflexões sobre necessidades de investigação nesta área.
description: Revista Turismo & Desenvolvimento, vol. 4 n.º 21/22 (2014)
A self-degradable hydrogel sensor for a nerve agent tabun surrogate through a self-propagating cascade
Creators: name: Lee, Doo-Hee
name: Valenzuela, Stephanie A.
name: Dominguez, Manuel N.
name: Otsuka, Mai
name: Milliron, Delia J.
name: Anslyn, Eric V.
Publisher: name: Elsevier
Year: 2021
Subjects: Hydrogels

description: Nerve agents that irreversibly deactivate the enzyme acetylcholin- esterase are extremely toxic weapons of mass destruction. Thus, developing methods to detect these lethal agents is important. To create an optical sensor for a surrogate of the nerve agent tabun, as well as a physical barrier that dissolves in response to this analyte, we devise a network hydrogel that decomposes via a self-propagating cascade. A Meldrums acid-derived linker is incor- porated into a hydrogel that undergoes a declick reaction in response to thiols, thereby breaking network connections, which re- leases more thiols, propagating the response throughout the gel. A combination of chemical reactions triggered by the addition of the tabun mimic initiates the cascade. The dissolving barrier is used to release dyes, as well as nanocrystals that undergo a spontaneous aggregation. Thus, this sensing system for tabun generates a phys- ical response and the delivery of chemical agents in response to an initial trigger.
From the mass gap in O(N) to the non-Borel-summability in O(3) and O(4) sigma-models
Creators: name: Volin, Dmytro
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We give an analytical derivation of the mass gap of the O(N) sigma models and investigate a large-order behavior of the weak coupling asymptotic expansion for the energy. For sufficiently large N the series is sign-oscillating, which is expected from the large N solution of the sigma model. However, for N=3 and N=4 the series are sign positive.
description: 4 pages; v2: +1 figure, typos corrected, formula (23) corrected; improved explanation and discussion throughout the text; references added
title: Ecografía doppler de pene; nuestra experiencia
Creators: name: Gordillo Arnaud, Jose Enrique
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Genital / Reproductive system male
subject: Echocardiography
subject: Ultrasound-Colour Doppler

description: Objetivos
Material y método
Resultados
Conclusiones
Bibliografía
description: Objetivos:
Recordar la anatomía,
vascularización y hallazgos ecográficos del pene. Exponer las principales indicaciones para la realización de este tipo de estudio y los hallazgos característicos de las distintas patologías. Exponer y analizar la...
Signature of Kondo breakdown quantum criticality in optical conductivity
Creators: name: Paul, I.
name: Civelli, M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the finite-frequency inter-band transition peak in the optical conductivity of a heavy fermion system close to a Kondo breakdown quantum critical point, where the lattice Kondo temperature vanishes. As the system approaches the phase transition from the heavy Fermi liquid side, we find a new cross-over regime where the peak position is related to, but is not directly proportional to, the lattice Kondo scale. In particular, the position of the peak moves to lower energies, but remains finite at the critical point. On the other hand, the peak value changes non-monotonically and eventually the peak disappears at the quantum critical point, indicating the decoupling of the narrow band of f-electrons from the conduction band. We argue that these are unique signatures of a Kondo breakdown transition, and therefore can be useful to distinguish it experimentally from a spin density wave instability.
description: 4 pages, 3 figures
title: Tungusic languages
title: Past and present
titleType: Subtitle
Creators: name: Hölzl, Andreas (Ed.)
name: Payne, Thomas E. (Ed.)
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Tungusic
subject: Siberia
subject: northern China
subject: 400 Sprache::410 Linguistik::410 Linguistik

description: Tungusic is a small family of languages, many of which are endangered. It encompasses approximately twenty languages located in Siberia and northern China. These languages are distributed over an enormous area that ranges from the Yenisey River and Xinjiang in the west to the Kamchatka Peninsula and Sakhalin in the east. They extend as far north as the Taimyr Peninsula and, for a brief period, could even be found in parts of Central and Southern China. This book is an attempt to bring researchers from different backgrounds together to provide an open-access publication in English that is freely available to all scholars in the field. The contributions cover all branches of Tungusic and a wide range of linguistic features. Topics include synchronic descriptions, typological comparisons, dialectology, language contact, and diachronic reconstruction. Some of the contributions are based on first-hand data collected during fieldwork, in some cases from the last speakers of a given language.
QCD phenomenology with infrared finite SDE solutions
Creators: name: Natale, A. A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recent progress in the solution of Schwinger-Dyson equations (SDE), as well as lattice simulation of pure glue QCD, indicate that the gluon propagator and coupling constant are infrared (IR) finite. We discuss how this non-perturbative information can be introduced into the QCD perturbative expansion in a consistent scheme, showing some examples of tree level hadronic reactions that successfully fit the experimental data with the gluon propagator and coupling constant depending on a dynamically generated gluon mass. This infrared mass scale acts as a natural cutoff and eliminates some of the ad hoc parameters usually found in perturbative QCD calculations. The application of these IR finite Green's functions in the case of higher order terms of the perturbative expansion is commented.
description: Talk at International Workshop on QCD Green's Functions, Confinement and Phenomenology, September 7-11, 2009, ECT, Trento, Italy, 12 pages, 7 figures
The effect of ship noise to marine mammals
Creators: name: Gkini, Fatmira
name: Γκίνι, Φατμίρα
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2023
Subjects: subject: Ηχορύπανση
subject: Θαλάσσια θηλαστικά
subject: Ναυτιλία
subject: Noise pollution
subject: Marine mammals
subject: Shipping

description: Η παρούσα διπλωματική εργασία αποτελεί έρευνα και καταγραφή γεγονότων και συμπερασμάτων για το θέμα «Η επίδραση του θορύβου των πλοίων στα θαλάσσια θηλαστικά». Στόχος της είναι να αναδείξει ένα πολύ σημαντικό πρόβλημα, αυτό της ηχορύπανσης, που αντιμετωπίζουν τα θαλάσσια θηλαστικά λόγω της συχνής διέλευσης των πλοίων από το φυσικο τους περιβάλλον. Παρακάτω θα αναλυθούν οι όροι της ναυτιλίας και των θαλάσσιων θηλαστικών, καθώς και η πορεία εξέλιξης της ναυτιλίας στο πέρασμα των χρόνων. Επίσης, θα αναλυθεί πώς επηρεάζονται τα θαλάσσια θηλαστικά και η ζωή τους στη θάλασσα από τη ναυτιλία, ενώ παράλληλα ο κ. Αλέξανδρος Φρατζής από το Ινστιτούτο Πέλαγος θα αναφέρει σημαντικά προβλήματα, μεταξύ των οποίων ο ήχος των πλοίων, που αντιμετωπίζουν τα θηλαστικά του θάλασσα στην Ελλάδα και κατ' επέκταση σε όλο τον κόσμο. Κλείνοντας, θα επισυμανθούν προτάσεις για τη μείωση του θορύβου που δημιουργούν τα πλοία στον ωκεανό, όπως η βελτίωση του σχεδιασμού των πλοίων για τη μείωση του υδροδυναμικού θορύβου που προκαλείται από τις έλικες, η μείωση της ταχύτητας των πλοίων, ο σχεδιασμός και η διαχείριση διαδρομής τους κ.λπ.
Critical success factors for tourism in developing countries: a critical reflection
Creators: name: Lima, Susana
name: Eusébio, Celeste
name: Partidário, Maria Do Rosário
Publisher: name: Journal of Tourism & Development
Year: 2014

description: The idea of using tourism as a tool for development has been established as a major priority by multilateral institutions, donors, governments, non-Governmental Organizations (NGO), national and international tourism bodies. Nevertheless, only few studies have analysed the factors that have had major impacts in such initiatives in developing countries. In order to overcome this gap, the main aim of this paper is to provide a comprehensive reflection about the critical factors that determine the success of the tourism development strategies adopted by developing countries. To accomplish this aim a literature review was conducted. The theoretical discussion suggests that there is a set of factors that should be evaluated when tourism is used as a tool for development. Despite the context in which this process takes place, the main focus of a tourism development strategy should necessarily approach a capacity-building reinforcement of the communities it strives to help. It will be postulated that these factors are essential to guarantee that the targeted communities are in full control and are the main beneficiaries of the whole development process.
description: Journal of Tourism & Development, vol. 4 n.º 21/22 (2014)
End-to-End Learning with Text & Knowledge Bases
Creators: name: Dhingra, Bhuwan
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: Communications Technologies not elsewhere classified

description:  Deep learning has been tremendously successful on tasks where the output prediction depends on a small, relatively clean input, such as a single image or a passage of text. But for many tasks, such as answering factoid questions or fact verification, the output depends on a broader context, or background knowledge, which goes beyond the input. Despite the best efforts to automatically create large knowledge bases, in most domains a majority of the information is only available in raw unstructured text. Harnessing this knowledge requires fine-grained language understanding at the document level, and scalable reasoning procedures to aggregate information across documents. While neural networks excel at the former, it is not clear how to scale them for the latter. On the other hand, symbolic representations such as knowledge graphs support scalable reasoning algorithms, but these are difficult to integrate with gradient-based learning. 
This thesis develops methods which leverage the strength of both neural and symbolic approaches. Specifically, we augment raw text with symbolic structure about entities and their relations from a knowledge graph, and learn task-specific neural embeddings of the combined data structure. We also develop algorithms for doing multi-step reasoning over the embeddings in a differentiable manner, leading to end-to-end models for answering complex queries. Along the way we develop variants of recurrent and graph neural networks suited to modeling textual and multi-relational data, respectively, and use transfer learning to improve generalization. Through a series of experiments on factoid question answering, task-oriented dialogue, language modeling, and relation extraction, we show that our proposed models perform complex reasoning over rich fine-grained information.
Freedom to travel ou freedom to trade? Uma análise crítica do discurso do WTTC
Creators: name: Hintze, Hélio
name: Júnior, António Ribeiro De Almeida
Publisher: name: Revista Turismo & Desenvolvimento
Year: 2014

description: O objetivo deste artigo é apresentar o discurso neoliberal do World Travel and Tourism Council (WTTC) e promover estudos críticos a respeito dos enunciados produzidos por tal entidade. Em vez de se apresentar como um organismo neutro que produz enunciados neutros sobre o turismo, o WTTC é um agente de mercado que tem claros interesses na produção da confusão entre as ideias de viagem (direito humano inalienável de se deslocar pelo mundo livre de constrangimentos) e turismo (forma capitalista da exploração destes deslocamentos legítimos). Tais interesses devem ser postos às claras na hora da produção dos significados do turismo. O objeto de análise deste artigo é o discurso da prioridade estratégia freedom to travel elaborada pelo organismo em questão. A Análise Crítica de Discursos foi a metodologia adotada. Com este trabalho procurou-se fazer com que aqueles que se envolvem com o turismo se posicionem dentro deste campo de disputas que tem o planeta como ‘tabuleiro’.
description: Revista Turismo & Desenvolvimento, vol. 4 n.º 21/22 (2014)
Effect of an instructional program on the use of the nursing process in practice
Creators: name: Boyle, Barbara Ann Joyce
Publisher: name: University of British Columbia
Year: 2010

description: The purpose of this study was to examine the effect of an instructional program on the utilization of the nursing process by graduate nurses in the practice area, and on the attitude of the graduate nurse toward the nursing process. Patient records were audited before and after completion of an instructional program to determine the extent to which the nursing process was being used. A questionnaire to determine attitude toward the nursing process that was held by the graduate nurse, was administered to the study and control groups before and after completion of the instructional program. It was hypothesized that there would be no measurable difference in: 1. the frequency with which a defined data base is obtained on individual patients; 2. the number of patient problems identified; 3. the number of patient problems which are consistent with established criteria; 4. the planning phase of the nursing process; 5. the implementing phase of the nursing process; 6. the evaluating phase of the nursing process; or 7. the way in which the graduate nurse views the nursing process, before and after completion of an instructional program by such graduate nurses. All seven null hypotheses were retained, although there was a statistical significance obtained in three of the criteria in the planning phase between the comparison groups of nurses. Those nurses having been exposed to the instructional program, scored higher as a group on the following criteria. These were: 1. expected behavioural outcomes are established; 2. the expected behavioural outcomes are realistic; and 3. the expected behavioural outcomes are related to patient problems identified in the assessment phase. From this study other variables have been identified concerning the use of the nursing process by graduate nurses in the clinical area and their attitude toward it. However, the major limitation of the study was thought to be the inability to compare each nurse's performance, in the study group, in the use of the nursing process before and after completion of the instructional program.
title: ¿Por qué no debemos prescindir de la Radiografía Lateral?
Creators: name: Quisiyupanqui, Kathy
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Conventional radiography
subject: Thorax

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Enfatizar el valor de la radiografía lateral de tórax revisando: - La anatomía normal y la sistemática de lectura que nos permite reconocer las estructuras y espacios de difícil visulaización en la proyección PA. - Los signos y hallazgos...
title: Nuevas aportaciones de la RM en las espondiloartropatias
Creators: name: Garcia Hernando, Thais Maria
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Inflammation
subject: MR
subject: Musculoskeletal spine

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Describir los hallazgos detectados mediante RM de sacroilíacas y de columna vertebral,
en los dos últimos años en el Hospital Universitario Fundación de Alcorcón,
solicitadas para el diagnóstico y la valoración de la respuesta al tratamiento...
Towards a solution of the cosmological constant problem
Creators: name: Klinkhamer, F. R.
name: Volovik, G. E.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The standard model of elementary particle physics and the theory of general relativity can be extended by the introduction of a vacuum variable which is responsible for the near vanishing of the present cosmological constant (vacuum energy density). The explicit realization of this vacuum variable can be via a three-form gauge field, an aether-type velocity field, or any other field appropriate for the description of the equilibrium state corresponding to the Lorentz-invariant quantum vacuum. The extended theory has, without fine-tuning, a Minkowski-type solution of the field equations with spacetime-independent fields and provides, therefore, a possible solution of the main cosmological constant problem.
description: 7 pages; v6: published version
Design and Implementation of Adaptive Game AI using Priority Matrices and Vector-Based Navigation
Creators: name: Gautam, Dikesh
name: Naik, Bhargav
name: Gohil, Aakash
name: Gawade, Sushant
Publisher: name: Zenodo
Year: 2025

description: In modern gaming, the realism and responsiveness of non-player characters (NPCs) significantly enhance player immersion and engagement. This paper proposes an adaptive. AI framework for NPCs using priority matrices for behavior selection and vector-based navigation for pathfinding and movement. The priority matrix evaluates environmental and internal game parameters to assign dynamic action priorities. Simultaneously, vector-based navigation enables fluid, real-time navigation in complex environments by computing motion vectors influenced by goal attraction, obstacle avoidance, and inertia. The hybrid framework was implemented in a custom game simulation built with Unity and C, demonstrating improved NPC adaptability and naturalistic behavior. Comparative evaluation shows our model enhances responsiveness and decision quality while maintaining computational efficiency. This paper details the design, implementation, and validation of the system, offering a novel and scalable approach to adaptive game AI.
title: Estudio mediante Resonancia Magnética de las enfermedades de la sustancia blanca
Creators: name: Nieto Parga, Angel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Head and neck
subject: Neuroradiology brain
subject: MR
subject: MR-Spectroscopy

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
-Describir los hallazgos en Resonancia Magnética de las entidades patológicas que más frecuentemente producen lesiones en la sustancia blanca. -Intentar facilitar el diagnóstico de estas entidades mediante la valoración de las características...
Origin of translocation barriers for polyelectrolyte chains
Creators: name: Kumar, Rajeev
name: Muthukumar, M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: For single-file translocations of a charged macromolecule through a narrow pore, the crucial step of arrival of an end at the pore suffers from free energy barriers, arising from changes in intrachain electrostatic interaction, distribution of ionic clouds and solvent molecules, and conformational entropy of the chain. All contributing factors to the barrier in the initial stage of translocation are evaluated by using the self-consistent field theory for the polyelectrolyte and the coupled Poisson-Boltzmann description for ions, without radial symmetry. The barrier is found to be essentially entropic, due to conformational changes. For moderate and high salt concentrations, the barriers for the polyelectrolyte chain are quantitatively equivalent to that of uncharged self-avoiding walks. Electrostatic effects are shown to increase the free energy barriers, but only slightly. The degree of ionization, electrostatic interaction strength, decreasing salt concentration and the solvent quality all result in increases in the barrier.
description: J.Chem. Phys. 131, 21 (2009) - to be appeared
title: De los nervios:  Valoración por ultrasonido con correlación por IRM
Creators: name: Escalona Huerta, Christian
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: Neuroradiology peripheral nerve
subject: Musculoskeletal soft tissue

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Familiarizarse con la exploración de nervios periféricos con ultrasonido dentro de la imagen musculoesquelética. Revisar las indicaciones y contraindicaciones de la exploración sonográfica de nervios periféricos. Revisar los aspectos técnicos...
O efeito da diversificação relacionada e não relacionada no desempenho financeiro de grupos empresariais na hotelaria: o caso português
Creators: name: Mota, Jorge Humberto
name: Almeida, Sara Cachide
name: Pardinha, João
name: Campos, António Miguel
Publisher: name: Revista Turismo & Desenvolvimento
Year: 2014

description: A crescente adoção de estratégias de diversificação de áreas negociais, na economia em geral, e no sector da hotelaria, em particular, suporta a pertinência de investigar o seu impacto ao nível de retorno e risco financeiros, no caso específico e não investigado de grupos empresariais do setor da hotelaria em Portugal. O problema de investigação anteriormente referido é complementado com a comparação de diferentes tipologias de diversificação (relacionada e não relacionada) e com a definição da metodologia adequada à sua quantificação, completando o enquadramento para a presente investigação. Esta tem como objetivos: (i) compreender se a adoção de uma determinada estratégia de diversificação no setor da hotelaria está associada a melhorias no retorno e estabilidade financeiros; (ii) averiguar se existem diferenças significativas ao nível do retorno e estabilidade financeiros resultantes da adoção de estratégias de diversificação relacionada e de diversificação não relacionada. Os resultados obtidos através da análise descritiva permitem concluir que a adoção de uma estratégia de diversificação relacionada traduz-se num melhor desempenho, tanto a nível do retorno como da estabilidade financeiros.
description: Revista Turismo & Desenvolvimento, vol. 4 n.º 21/22 (2014)
The effect of adding features on product attractiveness: the role of product perceived congruity
Creators: name: De Angelis, Matteo <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2008
Subjects: SECS-P/08 Economia e gestione delle imprese

description: Technological progress has been enabling companies to add disparate features to
their existing products. This research investigates the effect of adding more features
on consumers’ evaluation of the product, by examining in particular the role of the
congruity of the features added with the base product as a variable the moderates the
effect of increasing the number of features. Grounding on schema-congruity theory, I
propose that the cognitive elaboration associated with the product congruity of the
features added explains consumers’ evaluation as the number of new features
increases. In particular, it is shown that consumers perceive a benefit from increasing
the number of features only when these features are congruent with the product. The
underlying mechanisms that explains this finding predicts that when the number of
incongruent features increases the cognitive resources necessary to elaborate such
incongruities increase and consumers are not willing to spend such resources.
However, I further show that when encouraged to consider the new features
thoughtfully, consumers do seem able to infer value from increasing the number of
moderately incongruent features. Nonetheless, this finding does not apply for those
new features that are extremely incongruent with the product. Further evidence for
consumers’ ability to resolve the moderate incongruity associated with adding more
features is also shown, by studying the moderating role of temporal construal. I
propose that consumers perceive an increase in product evaluation as the number of
moderately incongruent features increases when consumers consider purchasing the
product in the distant future, whereas such an increase is not predicted for the near
future scenario. I verify these effect in three experimental studies. Theoretical and
managerial implications, and possible avenues of future research are also suggested.
Additional file 5 of Endolysins of bacteriophage vB_Sal-S-S10 can naturally lyse Salmonella enteritidis
Creators: name: Wang, Xinrui
name: Han, Lili
name: Rong, Jiaqing
name: Ren, Huiying
name: Liu, Wenhua
name: Zhang, Can
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 5.
Floer homology of cotangent bundles and the loop product
Creators: name: Abbondandolo, Alberto
name: Schwarz, Matthias
Publisher: name: arXiv
Year: 2008
Subjects: subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics

description: We prove that the pair-of-pants product on the Floer homology of the cotangent bundle of a compact manifold M corresponds to the Chas-Sullivan loop product on the singular homology of the loop space of M. We also prove related results concerning the Floer homological interpretation of the Pontrjagin product and of the Serre fibration. The techniques include a Fredholm theory for Cauchy-Riemann operators with jumping Lagrangian boundary conditions of conormal type, and a new cobordism argument replacing the standard gluing technique.
description: Fully revised version
Obtaining presentations from group actions without making choices
Creators: name: Putman, Andrew
Publisher: name: arXiv
Year: 2009
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: Consider a group $G$ acting nicely on a simply-connected simplicial complex $X$. Numerous classical methods exist for using this group action to produce a presentation for $G$. For the case that $X/G$ is 2-connected, we give a new method that has the novelty that one does not have to identify a fundamental domain for the action. Indeed, the resulting presentation is canonical in the sense that no arbitrary choices need to be made. It can be viewed as a nonabelian analogue of a simple result in the study of equivariant homology.
description: 24 pages, 8 figures. Some small corrections. To appear in Algebr. Geom. Topol
Innovazione organizzativa e istituzionale della pubblica amministrazione. Un approccio interpretativo e l'analisi di un dispositivo partecipativo nel settore della cultura
Creators: name: Dall’Agata, Claudia <1967>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2009
Subjects: SPS/09 Sociologia dei processi economici e del lavoro

description: The thesis aims at inquiring into the issue of innovation and organizational and institutional change in the public administration with regard to the increasingly massive adoption of participatory devices and practices in various arenas of public policies. The field of reference regards transformations of the types of public actions and regulation systems, concerning governance. Together with the crisis of the public function and of the role played by the insitutions what is emerging are different levels of governement, both towards an over national and a local direction, and a plurality of social interlocutors, followed by a post-bureaucratic pattern of the public administration that is opening itself in the direction of environment and citizens. The public adminstration is no longer considered an inert object within the bureaucratic paradigm but as a series of communicative processes, choices, cultures and practices that actively builds itself and the environment it interacts with. Therefore, the output of the public administration isn’t the simple service being supplied but the relationship enacted with the citizen, relationship that becomes the constituent basis of adminstrative processes.
The intention of thesis is to take into consideration the relation between innovation of the public administration and participatory experimentations and implementations regarded as exchanges in which citizens and the public administration hold talks and debates.
The issue of the organizational change of the public administration as output and effect of inclusive deliberative practices has been analysed starting from an institutionalist approach, in other words examining the constituent features of institutions, “rediscovering” them with regard to their public nature, their ability to elaborate collective values and meanings, the social definition of problems and solutions. The participatory device employed by the Forlì city council that involved enterprises and cultural associations of the area in order to build a participatory Table, has been studied through a qualitative methodology (participant observation and semi-strutctured interviews). The analysis inquired into the public nature both of the participatory device and the administrative action itself as well as into elements pertaining the deliberative setting, the regulative reference framework and the actors which took part in the process.
Estrutura econômica e turismo: o domínio local versus extra-local no distrito de Lavras Novas, Ouro Preto (Minas Gerais, Brasil)
Creators: name: Rosvadoski-Da-Silva, Patrícia
name: Gava, Rodrigo
name: Deboçã, Leonardo Pinheiro
Publisher: name: Revista Turismo & Desenvolvimento
Year: 2014

description: Neste artigo procurou-se analisar o desenvolvimento de uma fração territorial do município mineiro de Ouro Preto, o distrito de Lavras Novas, em função da dinâmica da atividade turística que o atinge. Objetivou-se compreender estrutura político-institucional do turismo no distrito de Lavras Novas e a relação entre os empreendimentos turísticos de domínio local e extra local. Assim, buscou-se a exploração de elementos teóricos a partir dos temas desenvolvimento local e turismo. A abordagem utilizada foi a qualitativa e os dados foram coletados por meio de entrevistas aos gerentes ou proprietários das pousadas e restaurantes, membros das entidades de representação dos nativos e representantes do poder público. A geração de emprego foi a principal variável sentida positivamente pelos moradores; contudo, percebeu-se uma predominância das pousadas e restaurantes dos proprietários externos fazendo com que o lucro ali gerado acabe beneficiando o lugar de origem do proprietário e, de forma minoritária, o distrito de Lavras Novas.
description: Revista Turismo & Desenvolvimento, vol. 4 n.º 21/22 (2014)
Effectiveness of teaching in the rehabilitation of patients with chronic bronchitis and emphysema
Creators: name: Perry, JoAnn
Publisher: name: University of British Columbia
Year: 2010

description: This study concerned itself with planned teaching, based on principles of adult education, as a component of the rehabilitation of patients with chronic bronchitis and emphysema. The need for teaching in this area has been recognized, but as yet not researched. The purpose of this study was to determine whether the teaching intervention, conducted in groups and on a one-to-one basis, would affect the patient's ability to recognize and treat his disease symptoms. The null hypothesis was tested: there is no significant difference in the patient's ability to recognize and treat disease symptoms after he has participated in a teaching program as compared to his ability to recognize and treat disease symptoms before participating in such a program. Using two rehabilitation facilities in large metropolitan hospitals, all patients accepted for the rehabilitation programs over a four-month period were asked to participate in the study. Ultimately, twenty patients made up the study group. Patients were instructed in diary-keeping skills and given one diary per week for four weeks before they began the rehabilitation program. These diaries were reviewed on a weekly basis with the researcher. After the patients had participated in the teaching program they were again given diaries (one per week for eight weeks) which were reviewed weekly with the researcher. The patients were asked to describe each day as being a good (comfortable) day or a bad (uncomfortable) day, to record the presence of any symptoms that they experienced, and to record any activities or treatments that they used to make themselves more comfortable. Twelve symptoms and eleven treatments were under consideration. The symptoms and treatments were divided into before and after categories and analyzed using the t ratio for non-independent groups. The results of the analysis lead to the rejection of the null hypothesis with p=0.05, indicating that patients with chronic bronchitis and emphysema were better able to cope with their illnesses after the teaching intervention. The study recommends that health care facilities establish teaching programs for patients with these illnesses, and that nurses assume greater involvement and responsiblity for teaching patients. The study concludes with recommendations for further investigation.
Structural and magnetic transition in CeFeAsO: separated or connected?
Creators: name: Jesche, A.
name: Krellner, C.
name: de Souza, M.
name: Lang, M.
name: Geibel, C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Using an adapted Sn-flux growth technique we obtained comparatively large CeFeAsO single crystals of better quality than previously reported polycrystals or single crystals, as evidenced by much sharper anomalies at the structural and magnetic phase transitions as well as a much higher residual resistivity ratio of 12. In the magnetically ordered phase we observe a very pronounced metallic behavior of the in-plane resistivity, which excludes a Mott insulator regime at low temperature. The separation Delta_T = T_0 - T_N between structural and magnetic ordering temperatures decreases with increasing sample quality, from 18 K in the initial reports to 6 K in the present single crystals, demonstrating that this separation is not an intrinsic property of the RFeAsO systems. Our results indicate that the coupling between magnetic ordering and structural distortion is very similar in AFe2As2 and RFeAsO type of compounds, much more similar than previously thought. The implications of our experimental results give arguments both in favor and against the nematic phase model.
description: published in PRB with the title 'Coupling between the structural and magnetic transition in CeFeAsO'