cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Women's engagement with and experience of interventions for antenatal and postnatal depression
Creators: name: McCarthy, Emma Michelle
Publisher: name: Macquarie University
Year: 2022
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified

description: A review of the relevant literature into prevention and treatment of postnatal depression (PND) reveals low acceptance rates for treatment, relatively high attrition. The following thesis set out to explore the acceptance and experience of treatment for postnatal depression. An investigation into the factors which influence women to accept treatment and maintain engagement was carried out with two separate groups of women in two separate contexts. The study employed qualitative methods in order to gain an in-depth understanding of the relevant issues. -- The first study carried out interviews with 15 'at risk' women who had taken part in a 9-week preventive cognitive-behavioural group program in an urban setting. Acceptance of treatment for these women appears to have been influenced by the non-stigmatising nature of the program. Furthermore it appears women found the group experience more beneficial than the program content. It is suggested social contact and support could be the crucial element both in terms of maintaining engagement and in preventing depression. -- In the second study 15 women who had received treatment and support from the community mental health service for postnatal depression were interviewed. Findings revealed that many women did not seek help until they reached 'crisis point' and a significant barrier to seeking more timely help was the stigma associated with the inability to cope with motherhood. Talking of their distress and experiences both with health professionals and other mothers is important both in terms of receiving help and aiding recovery. Finally, conclusions and clinical implications drawn from the two studies are discussed which includes suggestions for future health initiatives and interventions.
Incorporation of Liberal Education into the Engineering Curriculum at a Polytechnic
Creators: name: Berg, Devin
name: Lee, Tina
Publisher: name: figshare
Year: 2016
Subjects: subject: 91503 Engineering Practice
subject: FOS: Other engineering and technologies

description: A preprint of an article accepted for presentation at the 2016 American Society for Engineering Education Annual Conference and Exposition in New Orleans, LA, June 26-29, 2016.
AbstractTraditional engineering education often falls short when it comes to the inclusion of issues related to social justice, ethics, and globalization. While engineering programs are required to include ethics content for accreditation, most seem to rely primarily on general education electives, providing only a high-level overview and including the bare minimum in the program core. This can lead to an inconsistent student experience and minimal exposure to topics which are critically important for achieving worldwide equity and operating responsibly in the engineering workplace. Given the role that engineers play in economic development, this is unacceptable. It is therefore the responsibility of engineering educators to find a better way to shape the future of the engineering profession. This paper outlines the early efforts at integrating the topics of ethics, social justice, and social responsibility more directly into the engineering curriculum. This is approached from the perspectives of pedagogy, curriculum development, and service learning opportunities. It is within this context that the authors hope to influence students’ awareness of and connection to social and environmental issues as well as the ethical frameworks they develop and carry with them into their professional careers. This paper centers around the creation and delivery of a new introductory engineering course combining liberal education topics and introductory engineering topics. This course also includes a substantial design project which incorporates a cultural engagement component through collaboration with international partners. The first offering of this new course revealed that, while some reservations persist, students found value in exploring what it means to be an engineer in a broader global context.
Introduction of PEG-SANM nanocomposite as a new and highly efficient reagent for the promotion of the silylation of alcohols and phenols and deprotection of the silyl ethers
Creators: name: Shirini, Farhad
name: Abdollah Fallah Shojaei
name: Seyedeh Zahra Dalil Heirati
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Poly (ethylene glycol)-sulfonated sodium montmorillonite (PEG-SANM) nanocomposite was prepared by a simple method and characterized using XRD, TGA, SEM, TEM, and FT-IR techniques. After preparation and characterization, this reagent was used as a highly efficient and reusable solid acid catalyst for the chemoselective silylation of alcohols and phenols and deprotection of the obtained silyl ethers. The method offers several advantages including high to excellent yields of the products, short reaction times, easy preparation of the catalyst and easy work-up procedure. In addition, the catalyst can be recycled and reused at least for five times without significant decrease in the catalytic activity.
Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)
Creators: name: L. V. Laing
name: J. Viana
name: E. L. Dempster
name: M. Trznadel
name: L. A. Trunkfield
name: T. M. Uren Webster
name: R. Van Aerle
name: G. C. Paull
name: R. J. Wilson
name: J. Mill
name: E. M. Santos
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Bisphenol A (BPA) is a commercially important high production chemical widely used in epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous studies demonstrated that BPA activates estrogenic signaling pathways associated with adverse effects on reproduction in vertebrates and that exposure can induce epigenetic changes. We aimed to investigate the reproductive effects of BPA in a fish model and to document its mechanisms of toxicity. We exposed breeding groups of zebrafish (Danio rerio) to 0.01, 0.1, and 1 mg/L BPA for 15 days. We observed a significant increase in egg production, together with a reduced rate of fertilization in fish exposed to 1 mg/L BPA, associated with significant alterations in the transcription of genes involved in reproductive function and epigenetic processes in both liver and gonad tissue at concentrations representing hotspots of environmental contamination (0.1 mg/L) and above. Of note, we observed reduced expression of DNA methyltransferase 1 (dnmt1) at environmentally relevant concentrations of BPA, along with a significant reduction in global DNA methylation, in testes and ovaries following exposure to 1 mg/L BPA. Our findings demonstrate that BPA disrupts reproductive processes in zebrafish, likely via estrogenic mechanisms, and that environmentally relevant concentrations of BPA are associated with altered transcription of key enzymes involved in DNA methylation maintenance. These findings provide evidence of the mechanisms of action of BPA in a model vertebrate and advocate for its reduction in the environment.
A Strategic Research Agenda for Oceans and Human Health: Identifying priority research areas towards establishing an oceans and human health research capacity in Europe
Creators: name: H2020 SOPHIE Consortium
Publisher: name: Zenodo
Year: 2020
Subjects: ocean
human health
food
biodiversity
biotechnology
wellbeing
blue spaces
tourism
sustainability

description: Oceans and Human Health (OHH) is a meta-discipline exploring the complex and inextricable links between the health of the ocean and that of humans. It is our vision that OHH will be recognized as a core component of the Planetary Health concept, with OHH awareness spreading through all relevant fields and communities. This will help build the required OHH research capacity to understand the links between ocean health and human health, in order to optimize the outcomes for both. This Strategic Research Agenda (SRA) presents the necessary OHH research that will enable fundamental questions to be answered, evidence to be provided to policy, and OHH literacy to be increased in Europe and beyond.
[4+2]-Cycloaddition of sterically hindered thiophene S-oxides to alkenes and SO extrusion reactions of the cycloadducts
Creators: name: Thiemann, Thies
name: Iniesta, Jesus
name: Walton, David J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Cycloaddition reactions of 2,5-di-tert-butylthiophene S-oxide and 2,3,4,5-tetrakis(p-tolyl)thiophene S-oxide with alkenes are described. The reactivity of 2,5-di-tert-butylthiophene S-oxide as diene in Diels–Alder reactions is compared with 2,5-di-tert-butylthiophene S,S-dioxide. The thermal and photochemical SO extrusion reactions of the cycloadducts under formation of highly substitutedaromatic compounds are exemplified.
Maternity waiting homes and the shaping of maternal health policy in timor-leste
Creators: name: Wild, Kayli
Publisher: name: Charles Darwin University
Year: 2009

description: Timor-Leste's independence in 1999 provided an opportunity for Timorese health leaders, in conjunction with donors and technical advisors, to direct the nation's health policy agenda. Reducing the high rate of maternal mortality was a national priority. In 2005 a maternity waiting home policy was developed to improve access to care for women in rural and remote areas, and to facilitate a transition from birthing at home to birthing in hospital. By 2007 the concept had been incorporated into the Basic Services Package and was planned for every health post, health centre and hospital in the country. Drawing on the anthropology of policy and mixed methods research, this project uses maternity waiting homes as a case study to examine the factors that influence the development of maternal health policy and use of maternity services in Timor-Leste. An analysis of the policy process revealed complex power relationships which favoured the role of national elites when setting the policy agenda. Solutions tended to be based on dominant ideology rather than evidence. Despite strong national leadership, maternity waiting homes were transformed during implementation indicating 'street level bureaucrats' such as health managers and midwives had more control over implementation than expected. The maternity waiting homes in Timor-Leste were used as postpartum care facilities, mostly by women who lived within 5km of the health centre. They were not used by women to 'wait' prior to labour and did not improve access to hospital birth for women in remote areas. A range of qualitative and quantitative data is used to illustrate the importance of other issues affecting access to care, including individual, sociocultural, societal and health system factors. The failure of maternity waiting homes to meet national objectives highlights the need to invest in transport, decentralised birthing services and improved quality of care in hospitals. An alternative model of policy is presented, one which frames implementation as a process of adaptation. This model emphasises the need to re-evaluate the dominant approach to policy-making so that women's needs and the health system context inform the development and implementation of policies. It advocates for the participation of street level bureaucrats and rural women in setting a rural health policy agenda.
ЮҚОРИ МАРКАГА ЭГА БЎЛГАН БОҒЛОВЧИ МОДДАЛАР ОЛИШ УСУЛЛАРИ
Creators: name: Холова, Нодира
Publisher: name: Zenodo
Year: 2024

description: Ушбу мақолада юқори мустаҳкамликка эга бўлган боғловчи моддалар олишнинг  муаммоларини бартараф қилиш  яъни цементнинг муҳим экологик нуқсон  ва камчиликлари, уларни ишлаб чиқаришда кўп энергия талаб қилиниши, CО2 ва чангнинг катта чиқиндилари ажралиб чиқиши, экологияга зарарлари ва буларни олдини олиш бўйича қилинган ишлар ёритилган.
The Game Jam Guide
Creators: name: Cornish, Sara
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: classificationCode: 330310
subject: Interaction and experience design

description: How can designing games about real world issues teach students empathy, systems thinking, and design thinking? This curriculum guide shares lesson plans and ideas for educators to implement created by experts who lead game jams themed on topics such as climate change, immigration stories and local voices, and future cities.
Facile synthesis of bisphosphine monoxides from Morita–Baylis–Hillman carbonates
Creators: name: Zhou, Rong
name: Zhang, Kai
name: Rongfang Liu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Inorganic Chemistry
subject: 60506 Virology
subject: Computational Biology

description: A facile two-step synthesis of bisphosphine monoxides (BPMOs, with both the phosphine and phosphine oxide moieties within one molecule) from readily available Morita–Baylis–Hillman (MBH) carbonates was realized. Under the catalysis of DABCO, the MBH carbonates undergo allylic phosphorylation reaction with diphenylphosphine oxide or diethyl phosphonate to give monophosphine oxides bearing an activated alkene moiety; subsequent base-catalyzed hydrophosphination of the prepared monophosphine oxide with HPPh2 readily affords the BPMOs.
What’s Under the Big Tent?: A Study of ADHO Conference Abstracts
Creators: name: Weingart, Scott B.
name: Eichmann-Kalwara, Nickoal
Publisher: name: figshare
Year: 2016
Subjects: subject: Digital Humanities
subject: History
subject: Library and Information Studies
subject: FOS: Media and communications

description: This is a companion piece to our presentation at the 2015 DHSI Colloquium and to our manuscript with Jeanna Jorgensen, "Representation at Digital Humanities Conferences (2000-2015)" submitted to Feminist Debates in Digital Humanities, University of Minnesota Press (2017) [pre-print: dx.doi.org/10.6084/m9.figshare.3120610.v1].
Latitudinal regionalization of epibenthic macroinvertebrate communities on rocky reefs in the Gulf of California
Creators: name: Ulate, Karol
name: Sánchez, Carlos
name: Sánchez-Rodríguez, Alexandra
name: Alonso, David
name: Aburto-Oropeza, Octavio
name: Huato-Soberanis, Leonardo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: We report on a latitudinal pattern in the structure and species composition of epibenthic macroinvertebrate communities on rocky reefs along a gradient of eight degrees of latitude in the Gulf of California. We provide quantitative evidence of a prominent shift in the taxa dominating these communities, particularly the sessile taxa (Cnidaria, Bivalvia, Annelida, Ascidiacea and Porifera). This pattern was not found in non-sessile taxa (Echinodermata, Decapoda, Cephalopoda, Gastropoda and Polycladida). Based on Bray–Curtis similarity and indicator species analysis we found that the macroinvertebrates of rocky reefs in the Gulf of California are distributed in three broad regions, indicating that sessile taxa are creating such a structure and are related to environmental changes tied to latitude. The northern region (>28° N) was a temperate zone with the coolest water in winter and highest chlorophyll a concentrations, where Octocorallia of the genus Muricea were the dominant taxa. The central region (∼24–28° N) had a mix of oceanographic features of the northern and southern regions and was dominated by Echinodermata in terms of species richness and density. The southern region (<24° N) is a subtropical zone with typically warm and clear water, and dominated by Hexacorallia (stony corals). The southern area was less diverse and had lower densities than the central and northern areas. These three communities correspond to known oceanographic discontinuities in the Gulf of California. This implies that future coastal management plans and conservation efforts in the Gulf of California must be regionalized to support their distinct ecological communities.
“El que pone la música”: Reflexiones sobre un innecesario control del tribunal constitucional sobre la operación acordeón
Creators: name: Repositorio Academico UPC
name: Viña, César Enrique Bravo García
Publisher: name: figshare
Year: 2016
Subjects: subject: 150107 Taxation Accounting
subject: FOS: Economics and business
subject: 140215 Public Economics- Taxation and Revenue

description: A través del presente artículo, el autor establece el marco de las denominadas operaciones de acordeón de acuerdo a nuestra legislación societaria. Acto seguido comenta un conocido caso que se trata en sede constitucional a efectos de analizar los fundamentos más relevantes por los cuales de su sentencia fluiría que el Poder Judicial podría decidir sobre el futuro de la empresa en el marco de una operación financiera. ¿Podría acaso el máximo intérprete de la Constitución decidir qué hacer con el dinero ajeno aplicando el test de proporcionalidad?
Entretien de Rakan Fayiz Farhan al-Majali auprès de Yusuf al-Habashnah à propos du diwan de Dleywan al-Majali à Karak
Creators: name: al-Habashnah, Yusuf
name: Rakan Fayiz Farhan Al-Majali (Enquêteur)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/FileId-3139
description: Coverage: Karak, Jordanie
Beamforming and evaluation of focal plane arrays for radio astronomy
Creators: name: Hayman, Douglas Brian
Publisher: name: Macquarie University
Year: 2022
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified

description: Dense focal plane arrays (FPAs) are a key technology for a new generation of radiotelescopes. Their primary benefit is the rapid survey speed facilitated by the wide field-of-view provided by multiple beams. Recent advances have brought dense FPAs within reach of radio astronomy applications and a number of institutions have significant research programs in this field. The size of the FPA required for a specified field-of-view is an important parameter for preliminary system design. In this thesis, this is examined by calculating the encircled power in the focal plane using physical optics. Design data is provided relating the FPA size, dish size, focal length and field-of-view for prime focus reflectors. A broad minimum in the FPA size for a dish focal length and diameter ratio (F/D) of 0.4 is found and over practical geometries, the FPA size is dependent on only F/D and the scan angle times dish diameter divided by wavelength. The utility of this design data is confirmed by comparing it with current FPA system designs. In an operational radiotelescope, factors such as electronic gain drift and imperfect modelling result in the beamformer weights being best determined adaptively. Therefore a 'black-box' approach is used in this work. The theoretical basis for this approach is detailed; the determination of the gain (G) and system temperature (T) and the calculation of the maximum sensitivity (G/T) weighting are shown. A prototype interferometer-radiotelescope, built at CSIRO's Radiophysics Laboratory in Sydney, is used to demonstrate a suite of techniques for FPA beamforming and evaluation for this thesis. The method for calculating the maximum G/T weighting is demonstrated by applying the blackbox model to parameters that are readily extracted from an appropriately equipped radiotelescope.
The Augmented Museum: Essays on Opportunities and Uses of Augmented Reality in Museums
Creators: name: Kane, Elizabeth
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: classificationCode: 330310
subject: Interaction and experience design

description: Augmented reality (AR) can be an artistic choice or an experience augmentation for museum patrons. The Knight Foundation analyzed how museums are adapting to digital demands noting it is “vast” and “complicated.” The following collection from contributors to the Arts Management and Technology Laboratory offers perspectives on how museums are adapting to AR and similar digital disruptions.
Self-regulated learning at work (Upwork) pilot questionnaire
Creators: name: Margaryan, Anoush
Publisher: name: figshare
Year: 2016
Subjects: subject: 130108 Technical, Further and Workplace Education
subject: FOS: Educational sciences

description: Pilot questionnaire that was used to survey crowdworkers' learning practices within Upwork platform. Adapted from two instruments: SRLWQ and Davenport's Classification Structure of Knowledge-Intensive Processes (references below):
1) Fontana, P., Milligan, C., Littlejohn, A., & Margaryan, A. (2015). Measuring self-regulated learning in the workplace. International Journal of Training and Development, 19(1), 32-52.
2) Margaryan, A., Milligan, C., & Littlejohn, A. (2011). Validation of Davenport’s Classification Structure of Knowledge-intensive Processes. Journal of Knowledge Management, 15(4), 568-581.
With thanks to Alexandra Florea (Goethe University Frankfurt) for her feedback which helped improve the pilot questionnaire.
TeacherCraft: How Teachers Learn to Use MineCraft in Their Classrooms
Creators: name: Dikkers, Seann
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: classificationCode: 330310
subject: Interaction and experience design

description: Teacher Craft is about how teachers learn to use new digital media. Teacher learning is central to reform and change across subject areas and age levels, but how much do we really know about how teachers learn to try new lessons in classrooms? Minecraft is currently the game of choice for millions of youth and also for these seventeen teachers who claim it has transformed their classrooms. Its rapid adoption also provides a unique window of opportunity to look inside the recent memory of innovative teachers and unpack how they learned. Why did they pick Minecraft? More importantly, how did they pick Minecraft? Where did they hear about it? Who do they trust for ideas? How do they test new ideas? Can we begin to identify the trajectories of truly innovative teachers? It turns out, we can - and it may not be what you’d expect.
Self-regulated learning at work (CrowdFlower) pilot questionnaire
Creators: name: Margaryan, Anoush
Publisher: name: figshare
Year: 2016
Subjects: subject: 130108 Technical, Further and Workplace Education
subject: FOS: Educational sciences
subject: Sociology
subject: FOS: Sociology

description: Pilot questionnaire that was used to survey crowdworkers' learning practices within CrowdFlower platform. Adapted from two instruments: SRLWQ and Davenport's Classification Structure of Knowledge-Intensive Processes (references below):
1) Fontana, P., Milligan, C., Littlejohn, A., & Margaryan, A. (2015). Measuring self-regulated learning in the workplace. International Journal of Training and Development, 19(1), 32-52.
2) Margaryan, A., Milligan, C., & Littlejohn, A. (2011). Validation of Davenport’s Classification Structure of Knowledge-intensive Processes. Journal of Knowledge Management, 15(4), 568-581.
With thanks to Alexandra Florea (Goethe University Frankfurt) for her feedback which helped improve the pilot questionnaire.
Adams_UrbanEmissions.pptx
Creators: name: Adams, Matthew
Publisher: name: figshare
Year: 2016
Subjects: Geography

description: Presented during the McMaster University Big Ideas Better Cities Conference on April 20, 2016 in Hamilton, Ontario, Canada.
This work is part of the Environmental Component for the McMaster Institute for Transportation & Logistics' project: Social Costs and Benefits of Electric Mobility in Canada.
Editorial do n.º normal de julho da Indagatio Didactica
Creators: name: Bettencourt, Teresa
Publisher: name: Indagatio Didactica
Year: 2019

description: O presente número da Revista Online Indagatio Didactica é composto por dezasseis artigos distribuídos por quatro secções diferentes. Na secção Desenvolvimento Curricular e Didática apresentam-se nove artigos. As rubricas Avaliação em Educação e Tecnologias da Informação em Educação contam com dois trabalhos em cada e a secção Supervisão é composta por três artigos. Importa informar que, mais uma vez, recebemos um elevado número de submissões de propostas, reafirmando-se a vitalidade e o interesse da Revista. Aos novos autores e aos revisores que gentilmente aceitaram o convite dirigimos, desde já, o nosso reconhecido agradecimento.
description: Indagatio Didactica, vol. 11 n.º 1 (2019)
MASTER-SRLWQ-CrowdFlower270416.pdf
Creators: name: Margaryan, Anoush
Publisher: name: figshare
Year: 2016
Subjects: subject: 130108 Technical, Further and Workplace Education
subject: FOS: Educational sciences
subject: Sociology
subject: FOS: Sociology

description: Pilot questionnaire that was used to survey crowdworkers' learning practices within CrowdFlower platform. Adapted from two instruments: SRLWQ and Davenport's Classification Structure of Knowledge-Intensive Processes (references below):
1) Fontana, P., Milligan, C., Littlejohn, A., & Margaryan, A. (2015). Measuring self-regulated learning in the workplace. International Journal of Training and Development, 19(1), 32-52.
2) Margaryan, A., Milligan, C., & Littlejohn, A. (2011). Validation of Davenport’s Classification Structure of Knowledge-intensive Processes. Journal of Knowledge Management, 15(4), 568-581.
With thanks to Alexandra Florea (Goethe University Frankfurt) for her feedback which helped improve the pilot questionnaire.
Alkane oxidation catalysed by a self-folded multi-iron complex
Creators: name: Mettry, Magi
name: Moehlig, Melissa Padilla
name: Gill, Adam D.
name: Hooley, Richard J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Physiology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry

description: A preorganised ligand scaffold is capable of coordinating multiple Fe(II) centres to form an electrophilic CH oxidation catalyst. This catalyst oxidises unactivated hydrocarbons including simple, linear alkanes under mild conditions in good yields with selectivity for the oxidation of secondary CH bonds. Control complexes containing a single metal centre are incapable of oxidising unstrained linear hydrocarbons, indicating that participation of multiple centres aids the CH oxidation of challenging substrates.
Monsoonal and lunar variability in microzooplankton abundance and community structure in the Terusan mangrove creek (Malaysia)
Creators: name: Yong, Yu Lin
name: Chew, Li Lee
name: Lee, Choon Weng
name: Ving Ching Chong
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: This study documents the monsoonal and lunar effects on species composition and abundance of microzooplankton in a tropical estuary. We investigated microzooplankton abundance in relation to the various environmental and biotic parameters, sampled in the Matang mangrove (Malaysia) from April 2013 to February 2014. A total of 39 microzooplankton taxa comprising four major groups, i.e. loricate ciliates (37.72%), aloricate ciliates (29.46%), dinoflagellates (24.33%) and meroplanktonic nauplii (8.49%) were identified. The loricate ciliates were the most diverse group with 31 taxa recorded. Four major species of loricate ciliates were identified, i.e. Tintinnopsis beroidea, Tintinnopsis rotundata, Stenosemella avellana and Tintinnidium primitivum, while Strombidiidae and Strobilidiidae dominated the aloricate ciliates. Although small loricate ciliates were ubiquitous, redundancy analysis shows marked shifts in microzooplankton community structure, from one that was dominated by loricate ciliates during the drier SW monsoon, to aloricate ciliates at the onset of the wet NE monsoon, and then to dinoflagellates towards the end of the drier NE monsoon period. These shifts were associated with rainfall, dissolved inorganic nutrients, salinity, temperature and microbial food abundance. There was no clear lunar effect on abundance of microzooplankton except for Favella ehrenbergii and copepod nauplii, which were more abundant during neap than spring tides.
Metodologias ativas de ensino e aprendizagem: o emprego da aprendizagem baseada em desafios na elaboração de revisão de literatura
Creators: name: Moresi, Eduardo Amadeu Dutra
name: Filho, Mário De Oliveira Braga
name: Barbosa, Jair Alves
name: Hartmann, Vilson Carlos
Publisher: name: Indagatio Didactica
Year: 2019

description: Metodologias tradicionais de ensino e aprendizado no ensino super ior estão sendo questionadas se realmente são tão eficazes quanto se acredita que sejam. A aplicação de métodos inovadores de ensino e aprendizagem é essencial para motivar e gerar um espírito de aprendizagem e entusiasmo por parte dos estudantes, particularmente em relação à sua autonomia na autoria de textos científicos. Nesse sentido, a possibilidade do uso de novos recursos em prol do aprendizado evidenciam que novas práticas são necessárias para a fundamentação de temas de pesquisa. O objetivo deste artigo é apresentar o emprego da Aprendizagem Baseada em Desafios (ABD) para orientar a elaboração de revisão de literatura de temas de pesquisa. Para alcançar este objetivo, foi apresentada uma revisão de literatura sobre as metodologias ativas de ensino e aprendizagem, um referencial teórico sobre a ABD e um exemplo de emprego da metodologia na execução de pesquisa bibliográfica de um tema de pesquisa. A ABD, que é uma metodologia ativa de ensino, divide-se em três fases interligadas: engajar, pesquisar e agir. Toda a metodologia se apoia em um processo contínuo de documentação, reflexão e compartilhamento. O exemplo apresentado foca o tema Gestão da Inovação, cuja pesquisa bibliográfica foi realizada na base Scopus. Conclui-se que a aplicação da metodologia ABD orienta o pesquisador no processo de investigação e na elaboração de uma proposta mais fundamentada, além de trabalhar a construção da revisão de literatura.
description: Indagatio Didactica, vol. 11 n.º 3 (2019)
Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target
Creators: name: Beato, Claudia
name: Pecchini, Chiara
name: Cocconcelli, Chiara
name: Campanini, Barbara
name: Marialaura Marchetti
name: Pieroni, Marco
name: Mozzarelli, Andrea
name: Costantino, Gabriele
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: d-Serine is the co-agonist of NMDA receptors and binds to the so-called glycine site. d-Serine is synthesized by human serine racemase (SR). Over activation of NMDA receptors is involved in many neurodegenerative diseases and, therefore, the inhibition of SR might represent a novel strategy for the treatment of these pathologies. SR is a very difficult target, with only few compounds so far identified exhibiting weak inhibitory activity. This study was aimed at the identification of novel SR inhibitor by mimicking malonic acid, the best-known SR inhibitor, with a cyclopropane scaffold. We developed, synthesized, and tested a series of cyclopropane dicarboxylic acid derivatives, complementing the synthetic effort with molecular docking. We identified few compounds that bind SR in high micromolar range with a lack of significant correlation between experimental and predicted binding affinities. The thorough analysis of the results can be exploited for the development of more potent SR inhibitors.
SIMULATION ANALYSIS OF IMPLEMENTING END-AROUND TAXIWAY ON CROSSING RUNWAYS
Creators: name: Wang, Jiansen
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 460207
subject: Modelling and simulation
classificationCode: 350901
subject: Air transportation and freight services

description: At airports, aircraft taxi time may have effect on congestion, engine pollutants, and aircraft fuel consumption. An End-Around Taxiway (EAT) improves airport runway efficiencies and safety by providing a path for aircraft to move from one side of the runway to the other side without crossing that runway (FAA, 2022). The EAT has been implemented in four airports in the U.S.: Dallas/Fort Worth International Airport (KDFW), Hartsfield-Jackson International Airport (KATL), Detroit Metro Airport (KDTW), and Miami International Airport (KMIA) (Le, 2014). Currently, all the EATs are implemented at parallel runways. Previous research have shown that EAT on parallel runways has the potential to improve airport capacity and reduce fuel consumption (Fala et al., 2014; Feng & Johnson, 2021). There was no published application or research found about implementing EAT on crossing runways. This research is an explanatory study that focuses on analyzing the effect of EATs on airports with crossing runways. This research uses dynamic discrete event stochastic simulation software to build simulation models to analyze the effects of implementing EAT at crossing runways. Using a fictional airport loosely based on existing commercial service airports, the effect of EATs on a crossing runway airport was studied. The research has three experiments to measure the effects of the EAT in terms of taxi-in time, taxi-out time, and number of operations completed.The major findings of the research are: 1) using EAT for taxi-in operations significantly reduces the taxi-in time and taxi-out time at the fictional airport with crossing runways; 2) using EAT for taxi-out operation significantly increases taxi-in time at the fictional airport with crossing runways; 3) using EAT for taxi-out operations significantly reduces taxi-out times at the fictional airport with crossing runways; 4) there is no statistical significance found when implementing EAT at the fictional airport with crossing runways in terms of number of operations completed per day. The configuration of the airport, the number of operations, the weather, and other factors may affect the transfer of these results to other airports with crossing runways.Current EATs are only implemented and proposed at parallel runway airports. As aviation demand grows, this research may provide insights about a novel usage and operation strategy of EATs. The simulation model in this research is subject to assumptions and limitations. Future research is needed to improve the simulation model and further explore the effect of EATs on crossing runways.
Measuring the potential role of frailty in apparent declining efficacy of HIV interventions
Creators: name: Hardnett, Felicia P.
name: Rose, Charles E.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objective:In recent HIV intervention trials, intervention efficacies appear to decline over time. Researchers have attributed this to “waning,” or a loss of intervention efficacy. Another possible reason is heterogeneity in infection risk or “frailty.” We propose an approach to assessing the impact of frailty and waning on measures of intervention efficacy and statistical power in randomized-controlled trials. Methods:Using multiplicative risk reduction, we developed a mathematical formulation for computing disease incidence and the incidence rate ratio (IRR) as a function of frailty and waning. We designed study scenarios, which held study-related factors constant, varied waning and frailty parameters and measured the change in disease incidence, IRR, and statistical power. Results:We found that frailty alone can impact disease incidence over time. However, frailty has minimal impact on the IRR. The factor that has the greatest influence on the IRR is intervention efficacy and the degree to which it is projected to wane. We also found that even moderate waning can cause an unacceptable decrease in statistical power while the impact of frailty on statistical power is minimal. Discussion:We conclude that frailty has minimal impact on trial results relative to intervention efficacy. Study resources would, therefore, be better spent on efforts to keep the intervention efficacy constant throughout the trial (e.g., enhancing the vaccine schedule or promoting treatment adherence).
National Imaging Facility Museums Special Interest Group - Submission to the AAS Accessing Australia's Research Collections stakeholder consultation
Creators: name: Weisbecker, Vera
name: Fisher, Nicole
name: Goscinski, Wojtek
name: Kench, Peter
name: Keogh, Scott
name: Melville, Jane
name: Patalwala, Diana
name: Peachey, Thomas
name: Rampe, Michael
name: Tatarnic, Nik
Publisher: name: Zenodo
Year: 2024

description: This is a submission from the Australian National Imaging Facility Museums and Collections Special Interest Group (NIF Museums and Collections SIG) to the Australian Academy of Science "Accessing Australia’s Research Collections" stakeholder consultation. It was submitted on 8/6/2023.

The NIF Museums and Collections SIG is a community of practitioners from the natural history collections sector who are engaged with three-dimensional (3D) imaging of biodiversity collections. It includes curators, collection managers, academic researchers, digitisation and informatics staff, and staff of several NIF nodes who support the community’s imaging efforts.

This submission outlines the importance of 3D imaging in future-proofing biodiversity collections and sets the group's priorities for the digital future of Australia’s 3D biodiversity objects.
Teacher Pioneers
Creators: name: Williams, Caro
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: classificationCode: 330310
subject: Interaction and experience design

description: PART I. BUILDING GAMES FROM SCRATCH

1. WarLords!: Deconstructing Digital Games for Classroom Use By Seann Dikkers
2. Finding the Journal of Odysseus: Making and Using Alternate Reality Games in the Classroom By John Fallon
3. Beyond Gameplay—Using Role-Playing Game Creation to Teach Beowulf in a High School English Class By Kip Glazer
4. Immersive Learning—Using Role-Playing Games to Teach Creative Writing, Literature, and History By Trent Hergenrader
5. The Ward Game: How McMurphy, McLuhan, and MacGyver Might Free Us From McEducation By Paul Darvasi

PART II. USING PREEXISTING PLATFORMS 6. Conservation of Momentum By Cameron Pittman

7. Gone Home and the Apocalypse of High School English By Paul Darvasi
8. A Space to Create: Teaching With Minecraft By Jason Wilmot
9. Teaching Earth Science With Minecraft By Megan Pusey
10. Unlocking a Mystery: Designing a Resilient Place-Based Game By John Martin
11. Adventures in ARIS: The Affordances of Designing Place-Based Augmented Reality Games in the University Classroom By Laini Kavaloski

PART III. BROADENING THE GENRE

12. A First-Year Teacher’s Experience With PBL and Lego Robotics By William Vann
13. E-textiles to Teach Electricity: An Experiential, Aesthetic, Handcrafted Approach to Science By James Howell, Colby Tofel-Grehl, Deborah A. Fields, and Gabriella J. Ducamp
14. Kingdoms of Adarya: Considering the Ethics of a Game for Schooling By Lucas Cook and Sean C. Duncan
15. From Improvisational Puzzle to Interest-Driven Inquiry BY TIM SAUNDERS AND JEREMIAH KALIR
16. Teaching the Iterative Process Through Game Design and Development By Steve Isaacs
17. Teachers as Hackers: A New Approach to Teacher Professional Development Using a Hackathon Model By Kip Glazer and David Ng
18. Rewriting the Rules of School: A New Game to Play By Seann Dikkers
Conclusion: Good Game: On the Limitations of Puzzles and Possibilities for Gameful Learning By Jeremiah Kalir
Tabletop: Analog Game Design
Creators: name: Costikyan, Greg
Publisher: name: Carnegie Mellon University
Year: 2024
Subjects: classificationCode: 330310
subject: Interaction and experience design

description: DESIGNING TABLETOP GAMES

The Three-Player Problem Lewis Puslifer
Simulation Game Design James F. Dunnigan
Randomness, Player Choice, and Player Experience John Kaufeld
Dice as Dramaturge Chris Klug
Designing for Publishing JT Smith
Simply Knizia Kevin Jacklin
Filtering Feedback Ira Fay
15 Games in 15 Years Stone Librande

GAME ANALYSES

Settlers of Catan Ian Schreiber
Conquest David Parlett
Fair Isn't Funny: The Design of Cosmic Encounter Peter Olotka
The Greatest Gift Ray Mazza
Pandemic John Sharp
Design Lessons from Poker Richard Garfield
Ra Brian Magerko
Train Simon Ferrari
Twilight Struggle Pat Harrigan and Noah Wardrip-Fruin

THE STUDY OF TABLETOP GAMES

Understanding Strategic Boardgames as Computational Thinking Training Machines Matthew Berland
Boardgame Aesthetics Greg Costikyan
Improv Brenda Bakker Harger
Investigação Qualitativa de Práticas Pedagógicas: O Caso Particular da Formação Docente
Creators: name: Cilleros, María Victoria Martín
name: De Castro, Paulo Alexandre
name: De Oliveira E Sá, Susana Emília Vaz
Publisher: name: Indagatio Didactica
Year: 2019

description: Foram selecionados 13 (treze) dos artigos apresentados na 7ª edição do Congresso Ibero-Americano em Investigação Qualitativa, CIAIQ de 2018 — que ocorreu entre os dias 10 e 13 de julho de 2018, nas instalações da UNIFOR – Universidade de Fortaleza, na cidade de Fortaleza — como forma de reconhecer e premiar alguns dos melhores trabalhos de investigação qualitativa desenvolvidos pela comunidade Ibero-Americana. Este número especial da revista é uma colaboração exitosa entre a Revista Indagatio Didactica e o CIAIQ, o resultado de esforços contínuos e conjuntos de internacionalização e de promoção da investigação qualitativa nas diversas áreas de conhecimento. É importante informar que, cada um dos 13 (treze) artigos deste número especial foi selecionado por um comité interno ad hoc do CIAIQ, e, na sequência, passou por nova avaliação técnica e revisão por pares, seguida de uma última revisão técnica para concluir todo o processo e garantir um número especial da Revista Indagatio Didactica de alta qualidade e de interesse para os seus leitores. Por fim, releva-se que todos os artigos deste número especial da Revista Indagatio Didactica foram alterados e aprofundados em relação às versões publicadas nas atas do CIAIQ de 2018, para assim merecerem esta publicação. O tema que uniu/aproximou todos os 13 (treze) artigos — que em princípio abordam assuntos distintos — foi a pesquisa/investigação de práticas pedagógicas e, em particular, na formação de docentes.
description: Indagatio Didactica, vol. 11 n.º 3 (2019)
The history and rationale of using carbonic anhydrase inhibitors in the treatment of peptic ulcers. In memoriam Ioan Puşcaş (1932–2015)
Creators: name: Buzás, György M.
name: Supuran, Claudiu T.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Carbonic anhydrase (CA, EC 4.2.1.1) inhibitors (CAIs) started to be used in the treatment of peptic ulcers in the 1970s, and for more than two decades, a group led by Ioan Puşcaş used them for this purpose, assuming that by inhibiting the gastric mucosa CA isoforms, hydrochloric acid secretion is decreased. Although acetazolamide and other sulfonamide CAIs are indeed effective in healing ulcers, the inhibition of CA isoforms in other organs than the stomach led to a number of serious side effects which made this treatment obsolete when the histamine H2 receptor antagonists and the proton pump inhibitors became available. Decades later, in 2002, it has been discovered that Helicobacter pylori, the bacterial pathogen responsible for gastric ulcers and cancers, encodes for two CAs, one belonging to the α-class and the other one to the β-class of these enzymes. These enzymes are crucial for the life cycle of the bacterium and its acclimation within the highly acidic environment of the stomach. Inhibition of the two bacterial CAs with sulfonamides such as acetazolamide, a low-nanomolar H. pylori CAI, is lethal for the pathogen, which explains why these compounds were clinically efficient as anti-ulcer drugs. Thus, the approach promoted by Ioan Puşcaş for treating this disease was a good one although the rationale behind it was wrong. In this review, we present a historical overview of the sulfonamide CAIs as anti-ulcer agents, in memoriam of the scientist who was in the first line of this research trend.
YOSHLAR XULQ-ATVORIDA MILLIY FAZILATLARNI SHAKLLANTIRISHNING IJTIMOIY-PSIXOLOGIK OMILLARI
Creators: name: Adilova, Aziza
name: Jabborov, Xazrat
Publisher: name: Zenodo
Year: 2025

description: Yoshlar xulq-atvorida miliy fazilatlarni ijtimoiy-psixologik omillari haqida gap ketganda beixtiyor taniqli o‘zbek ma'rifatparvari Abdulla Avloniyning “Tarbiya biz uchun yo hayot - yo mamot, yo najot - yo halokat, yo saodat - yo falokat masalasidir” degan chuqur  ma'noli so‘zlari inson e'tiborini tortadi [2, s.108-118].