cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
FACULTY BELIEFS AND ORIENTATIONS TO TEACHING AND LEARNING IN THE LAB: AN EXPLORATORY CASE STUDY
Creators: name: Coutinho, Genisson Silva
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace engineering not elsewhere classified
Chemical engineering design
Chemical engineering not elsewhere classified
Civil engineering not elsewhere classified
Digital processor architectures
Other information and computing sciences not elsewhere classified
Electrical engineering not elsewhere classified
Materials engineering not elsewhere classified
Mechanical engineering not elsewhere classified

description: This dissertation presents a two-phase multiple case study conducted to investigate the facultybeliefs regarding the integration of labs into engineering and engineering technology educationand the relationship between such beliefs and the teaching practices adopted in the labs. In the firstphase, an exploratory study grounded on a framework of beliefs was conducted to elicit the beliefsespoused by the participants. Interviews were used to elicit the participants’ beliefs. Thetranscribed interviews were analyzed through the constant comparative method. Thirteen facultymembers from the College of Engineering and Engineering Technology participated. In the secondphase, a triangulation approach was used to investigate the relationships between the participants’beliefs and their corresponding teaching practices. The findings from phase one were triangulatedwith the data from interviews, questionnaires, and documents to elicit the relationships betweenbeliefs and practices.
Socioeconomic Inequalities in Health and Perceived Unmet Needs for Healthcare among the Elderly in Germany
Creators: name: Hoebel, Jens
name: Rommel, Alexander
name: Schröder, Sara Lena
name: Fuchs, Judith
name: Nowossadeck, Enno
name: Lampert, Thomas
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: health inequalities
subject: socioeconomic position
subject: social determinants
subject: health disparities
subject: unmet needs
subject: access to health services
subject: healthy ageing
subject: 610 Medizin

description: Research into health inequalities in the elderly population of Germany is relatively scarce. This study examines socioeconomic inequalities in health and perceived unmet needs for healthcare and explores the dynamics of health inequalities with age among elderly people in Germany. Data were derived from the Robert Koch Institute’s cross-sectional German Health Update study. The sample was restricted to participants aged 50–85 years (n = 11,811). Socioeconomic status (SES) was measured based on education, (former) occupation, and income. Odds ratios and prevalence differences were estimated using logistic regression and linear probability models, respectively. Our results show that self-reported health problems were more prevalent among men and women with lower SES. The extent of SES-related health inequalities decreased at older ages, predominantly among men. Although the prevalence of perceived unmet needs for healthcare was low overall, low SES was associated with higher perceptions of unmet needs in both sexes and for several kinds of health services. In conclusion, socioeconomic inequalities in health exist in a late working age and early retirement but may narrow at older ages, particularly among men. Socially disadvantaged elderly people perceive greater barriers to accessing healthcare services than those who are better off.
An mRNA-based seasonal influenza vaccine in adults: Results of two phase 3 randomized clinical trials and correlate of protection analysis of hemagglutination inhibition titers
Creators: name: Kandinov, Boris
name: Soens, Mieke
name: Huang, Wenmei
name: Llapur, Conrado
name: Ensz, David
name: Essink, Brandon
name: Fierro, Carlos
name: Vakil, Jignesh
name: Pucci, Alicia
name: Guo, Jia
name: Rudden, Sinead
name: Hall, Kristi
name: Hicks, Bryony
name: Schaefers, Kristin
name: Zhou, Honghong
name: Ma, Chong
name: Zheng, Lingyi
name: Avanesov, Andrei
name: Park, Yoonyoung
name: Du, Evelyn
name: Miller, Jacqueline
name: Ananworanich, Jintanat
name: Nachbagauer, Raffael
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The safety, immunogenicity, and efficacy of the original formulation of the investigational mRNA-1010 vaccine for seasonal influenza were investigated in two randomized, active-controlled, phase 3 trials in adults (NCT05415462 and NCT05566639), and the results were used to evaluate hemagglutination inhibition (HAI) titers as correlates of risk and protection against influenza-like illness. mRNA-1010 (50-µg) demonstrated an acceptable reactogenicity and safety profile among the >14,000 adult participants vaccinated in both trials. The efficacy profile of mRNA-1010 was generally reflective of immunogenicity findings, with higher immune responses against influenza A strains and lower responses against influenza B strains relative to an active comparator (licensed inactivated influenza vaccine). An analysis of HAI titers as a correlate of protection against influenza infection provided support for its use as a surrogate endpoint for mRNA-1010, similar to licensed influenza vaccines. These findings support further optimization and development of mRNA-1010 against seasonal influenza.
Continuity of care by a primary midwife (caseload midwifery): a cost analysis using results from the COSMOS randomised controlled trial
Creators: name: Callander, Emily J
name: Jackson, Hannah
name: McLachlan, Helen
name: Davey, Mary-Ann
name: Forster, Della
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3215
subject: Reproductive medicine
classificationCode: 4204
subject: Midwifery
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: Introduction: Caseload midwifery (continuity of midwifery carer) offers benefits including lower caesarean section rates, lower risks of preterm birth and stillbirth, and improved maternal satisfaction of care. Despite these advantages, concerns about additional costs hinder widespread implementation. This study examines the cost of caseload midwifery compared with standard maternity care from the perspective of both public hospitals and public funders.Methods: A cost analysis was conducted using data from a randomised controlled trial of 2314 low-risk pregnant women in Melbourne, Australia. Women randomised to caseload care received antenatal, intrapartum and postpartum care from a primary midwife, with some care provided by a ‘back-up’ midwife. Women in standard care received midwifery-led care with varying levels of continuity, junior obstetric care or community-based medical care. The cost analysis compared differences in mean costs of health resources to public hospitals and to public funders. Additionally, a budget impact analysis estimated total costs to the health system between 2023 and 2027.Results: For public hospitals, there was no significant difference in overall costs between women receiving caseload midwifery (n=1146) versus standard care (n=1151) ($A12 363 (SD: $A4967) vs $A12 323 (SD: $A7404); p=0.85). Conversely, public funders incurred lower expenditures for women receiving caseload midwifery ($A20 330 (SD: $A8312)) versus standard care ($A21 637 (SD: $A11 818); p <0.001). The budget impact analysis estimated savings of $A625 million to the health system over the next 5 years with expanded access to caseload midwifery in Australia.Conclusion: Caseload midwifery in low-risk women is cost-neutral to public hospitals and cost-saving to public funders.Tweetable abstractContinuity of midwifery for low-risk women reduces costs to public funders, with no additional costs to hospitals.
Soziale Unterschiede bei den Notarztdiagnosen Herzinfarkt und Schlaganfall
Creators: name: Hanefeld, Christoph
name: Haschemi, Alexander
name: Lampert, Thomas
name: Trampisch, Hans J.
name: Mügge, Andreas
name: Miebach, Janine
name: Kloppe, Cordula
name: Klaaßen-Mielke, Renate
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2018
Subjects: subject: 610 Medizin

description: Hintergrund: Dass Personen mit niedrigem sozioökonomischen Status ein höheres Krankheitsrisiko haben, trifft gerade mit Blick auf schwerwiegende und chronische Erkrankungen zu. Hinsichtlich akuter notfallmedizinischer Erkrankungen liegen aktuelle Studien mit größerer Fallzahl nicht vor. Methode: Im Rahmen der retrospektiven Studie wurden alle Notarzteinsätze der Stadt Bochum sowie die notärztlichen Diagnosen (2014/2015) erfasst (16 767 Einsätze). Als Indikator für die sozioökonomische Situation eines Ortsteils wurde die Arbeitslosenquote (Anteil der registrierten Arbeitslosen an der Bevölkerung am Hauptwohnsitz im Alter von 15 bis unter 65 Jahren) verwendet. 12 168 Einsätze wurden schließlich nach notärztlichen Diagnosen gruppiert und für die drei am stärksten besetzten Obergruppen (kardiovaskuläre, neurologische und pulmologische Notfälle), auf die annähernd zwei Drittel aller Diagnosen entfallen, krankheitsbezogen ausgewertet. Ergebnisse: Die notärztlichen Gesamteinsatzraten nehmen mit steigender Arbeitslosenquote zu. Nach Adjustierung für die potenziell zur Effektvermengung führenden Variablen (Confounder) Alter und Geschlecht zeigt sich in den Einsatzraten ein signifikanter Trend (p < 0,01). Für die Gesamteinsatzrate steigt das indirekt standardisierte Ratenverhältnis (IRR) von 0,841 (95-%-Konfidenzintervall: [0,808; 0,875]) bei einer Arbeitslosenquote von weniger als 5 % auf 1,212 [1,168; 1,256] bei einer Arbeitslosenquote von 9,5 % und mehr. Auch die Differenzierung in die diagnosespezifischen Einsatzraten erbrachte in den drei Obergruppen (kardiovaskuläre, neurologische, pneumologische Erkrankungen) sowie bei den jeweiligen häufigsten Einzeldiagnosen (akutes Koronarsyndrom/Herz-Kreislauf-Stillstand [n = 1 498], transitorische ischämische Attacke/Insult/intrazerebrale Blutung [n = 1 274], Asthma/chronisch obstruktive Lungenerkrankung [n = 663]) das gleiche Ergebnis. Schlussfolgerung: Die vorliegende Untersuchung zeigt, dass die notärztliche Einsatzrate in sozial benachteiligten Stadtteilen signifikant erhöht ist. Dieses zeigt sich sowohl bei der Gesamtzahl der Notarzteinsätze als auch in der Betrachtung der einzelnen Erkrankungen. Somit wird eine gesamtgesellschaftliche Problematik erkennbar, die bei der Rettungsdienstorganisation konkret berücksichtigt werden sollte.
Helena. La soledad en el laberinto. Epistolario de Helena Laura Paz Garro y Ernst Jünger, por: Elsa Margarita Schwarz Gasque y María del Carmen Vázquez Martínez, ISBN: 9786078706433, Ediciones del Lirio, 2020.
Creators: name: Kriza, Elisa
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Right-wing extremists
subject: Racism in literature
subject: National socialism
subject: Women in literature
subject: World War (1939-1945)
subject: Mexico
subject: France
subject: Germany

description: This is a book review that evaluates the Spanish-language edition of the letters written by the Mexican poet Helena Paz Garro to the German writer Ernst Jünger, which were originally written in French. The reviewer had access to the original letters in the German Literature Archive in Germany and she compares the original texts with the translation, which was poorly carried out. The reviewer underlines the importance of these letters in the critical exploration of Mexican right-wing thought and the study of Nazi sympathizers from Mexico, as the poet Paz Garro was attracted to Jünger and his circle due to their participation in WWII on the German side. The reviewer notes the lack of adequate historical and cultural contextualizaton by the editors of the Spanish-language edition of these letters.
Additional file 1 of Re-investigation of functional gastrointestinal disorders utilizing a machine learning approach
Creators: name: Mousavi, Elahe
name: Keshteli, Ammar Hasanzadeh
name: Sehhati, Mohammadreza
name: Vaez, Ahmad
name: Adibi, Peyman
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1.
Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA)
Creators: name: Burwinkel, Michael
name: Lutzenberger, Manuel
name: Heppner, Frank L.
name: Schulz-Schaeffer, Walter
name: Baier, Michael
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2018
Subjects: subject: 610 Medizin

description: Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference to prions, not only in terms of pathogenesis but also in terms of potential transmission of disease. We partially characterized the seeded Aβ amyloidosis after intracerebral injection of various brain homogenates in APP/PS1 mice. One particularly seed-laden homogenate was selected to investigate the development of Aβ pathologies after intravenous exposure. We report here that a single intravenous injection of an Alzheimer disease patient’s-brain extract into APP/PS1 recipient mice led to cerebral amyloid angiopathy within 180 days post injection. Thus, vascular proteinopathies such as CAA are transmissible in mice via the intravenous route of peripheral exposure.
SPARSE DISCRETE WAVELET DECOMPOSITION AND FILTER BANK TECHNIQUES FOR SPEECH RECOGNITION
Creators: name: Dai, Jingzhao
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified

description: Speech recognition is widely applied to translation from speech to related text, voice driven commands, human machine interface and so on [1]-[8]. It has been increasingly proliferated to Human’s lives in the modern age. To improve the accuracy of speech recognition, various algorithms such as artificial neural network, hidden Markov model and so on have been developed [1], [2]. In this thesis work, the tasks of speech recognition with various classifiers are investigated. The classifiers employed include the support vector machine (SVM), k-nearest neighbors (KNN), random forest (RF) and convolutional neural network (CNN). Two novel features extraction methods of sparse discrete wavelet decomposition (SDWD) and bandpass filtering (BPF) based on the Mel filter banks [9] are developed and proposed. In order to meet diversity of classification algorithms, one-dimensional (1D) and two-dimensional (2D) features are required to be obtained. The 1D features are the array of power coefficients in frequency bands, which are dedicated for training SVM, KNN and RF classifiers while the 2D features are formed both in frequency domain and temporal variations. In fact, the 2D feature consists of the power values in decomposed bands versus consecutive speech frames. Most importantly, the 2D feature with geometric transformation are adopted to train CNN. Speech recognition including males and females are from the recorded data set as well as the standard data set. Firstly, the recordings with little noise and clear pronunciation are applied with the proposed feature extraction methods. After many trials and experiments using this dataset, a high recognition accuracy is achieved. Then, these feature extraction methods are further applied to the standard recordings having random characteristics with ambient noise and unclear pronunciation. Many experiment results validate the effectiveness of the proposed feature extraction techniques.
Safety and immunogenicity of a bivalent norovirus vaccine candidate in infants from 6 weeks to 5 months of age: A phase 2, randomized, double-blind trial
Creators: name: Sáez-Llorens, Xavier
name: deAntonio, Rodrigo
name: López-Medina, Eduardo
name: López, Pío
name: Masuda, Taisei
name: Mendelman, Paul M
name: Sherwood, Jim
name: Baehner, Frank
name: Borkowski, Astrid
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: As infants suffer significant morbidity and mortality due to norovirus-related acute gastroenteritis (AGE), we assessed four formulations of the bivalent virus-like particle (VLP) vaccine candidate (HIL-214) in Panamanian and Colombian infants. 360 infants aged 6 weeks to 5 months were randomly allocated to 8 groups to receive three doses of HIL-214 or two doses of HIL-214 and one dose of placebo (Days 1, 56 and 112), where HIL-214 doses contained 15/15, 15/50, 50/50 or 50/150 μg of GI.1/GII.4c genotype VLPs and 0.5 mg Al(OH)3. Solicited injection-site and systemic adverse events (AE) were collected within 7 days after each dose, unsolicited AEs were collected within 28 days after each, and serious AEs throughout the study. Pan-Ig and histoblood group antigen-blocking antibodies (HBGA) were measured on Days 1, 56, 84, and 140. All formulations were well-tolerated causing mainly mild-to-moderate transient solicited AEs, most frequently local pain and irritability/fussiness, but no vaccine-related serious AEs. Two doses of each formulation induced high titers of high avidity Pan-Ig and also HBGA antibodies; a third dose increased titers against both antigens and the avidity of Pan-Ig antibodies against GII.4c but not against GI.1. Two and three doses of HIL-214 were well-tolerated and induced potent immune responses at 4–6 months of age supporting further clinical assessment to protect against norovirus-related AGE.
Erfassung inzidenter kardiovaskulärer und metabolischer Erkrankungen in epidemiologischen Kohortenstudien in Deutschland
Creators: name: Herrmann, Wolfram J.
name: Weikert, Cornelia
name: Bergmann, Manuela
name: Boeing, Heiner
name: Katzke, Verena A.
name: Kaaks, Rudolf
name: Tiller, Daniel
name: Greiser, Karin Halina
name: Heier, Margit
name: Meisinger, Christa
name: Schmidt, Carsten Oliver
name: Neuhauser, Hannelore
name: Heidemann, Christin
name: Jünger, Claus
name: Wild, Philipp S.
name: Schramm, Sara Helena
name: Jöckel, Karl-Heinz
name: Dörr, Marcus
name: Pischon, Tobias
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2018
Subjects: subject: Epidemiologie
subject: Risikofaktoren
subject: Kohortenstudien
subject: Herz-Kreislauf-Krankheiten
subject: Metabolische Krankheiten
subject: 610 Medizin

description: Hintergrund: Kardiovaskuläre und metabolische Erkrankungen sind häufige Ursachen für Mortalität und Verlust von Lebensqualität in der deutschen Bevölkerung. Zur Erforschung von Risikofaktoren sind populationsbasierte Kohortenstudien notwendig. Für deren Aussagekraft ist die vollständige und valide Erfassung der Endpunkte ein zentraler Aspekt. Fragestellung: Ziel war es, derzeit in Deutschland durchgeführte populationsbasierte Kohortenstudien mit bereits erreichten inzidenten kardiovaskulären und metabolischen Erkrankungen (Herzinfarkt, Diabetes mellitus Typ 2, Schlaganfall, Herzinsuffizienz und arterielle Hypertonie) zu identifizieren und methodische Aspekte der Erfassung und Klassifikation in diesen Studien zusammenzutragen. Methoden: Über die Arbeitsgruppe „Epidemiologie der Herz-Kreislauf- und Stoffwechsel-Erkrankungen“ wurden deutsche bevölkerungsbasierte Kohortenstudien mit bereits erreichten inzidenten kardiovaskulären und metabolischen Erkrankungen identifiziert. Vertretende Personen dieser Studien wurden im Rahmen eines Workshops eingeladen, ihre Vorgehensweise vorzustellen und im Nachgang systematisch zu ergänzen und aufzubereiten. Ergebnisse: Es wurden 8 Studien aus verschiedenen Regionen mit insgesamt 100.571 Teilnehmern und einer Altersspanne von 18–83 Jahren identifiziert. Die Selbstauskunft der Studienteilnehmenden ist die wichtigste Quelle zur Veranlassung weiterer Recherchen zur Erfassung der Endpunkte in diesen Studien. Die Selbstangaben werden in allen 8 Studien mithilfe verschiedener Informationen aus anderen Datenquellen, z. B. Unterlagen von behandelnden Ärzten oder Kliniken, ergänzt und abschließend bewertet. Diskussion: Unsere Ergebnisse zeigen die zentrale Bedeutung der Selbstauskunft und den Aufwand der erforderlichen Validierung der Endpunkte. Künftige Studien können diese Informationen in der Planung berücksichtigen und standardisieren.
ASSEMBLY OF ARTHROPOD COMMUNITIES IN RESTORED PRAIRIE, OLD FIELD AND MONOSPECIFIC STAND OF PHALARIS ARUNDINACEA: A FUNCTIONAL PERSPECTIVE
Creators: name: Kelleher, Eric M
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Conservation and biodiversity
Ecology not elsewhere classified
Ecosystem function
Environmental management
Environmental assessment and monitoring
Wildlife and habitat management
Natural resource management

description: Effects of prairie restoration on arthropod diversity was investigated at Gabis Arboretum, Valparaiso, Indiana. A total of 35,408 arthropods belonging to 13 taxa in the restored prairie (RP1 and RP2), old field (OF), and monoculture stand of Phalaris arundinacea (reed canary grass – RCG) sites, were captured, counted, and compared. The enhanced plant species diversity in the restored prairies did not appear to promote the diversity of arthropod taxa. However, the restoration led to a more balanced composition of arthropod functional groups and thus elevated the diversity of functional groups. The arthropod assemblages in the three sites diverged clearly according to my canonical correspondence analysis (CCA) ordination. Pollinator abundance was greatest at RP and least at RCG site, positively correlating with greater forb diversity, and suggesting greater potential for nectar feeding and pollination potential at RP sites. Herbivore abundance was greatest at the RP sites, positively correlating with increasing plant species diversity. Predator abundance was significantly greater at the RCG site compared to the OF and RP sites; it was positively correlated with greater C3 grass cover, a characteristic of the structurally homogenous RCG site, and negatively correlated with increasing plant diversity and forb cover, a characteristic of the diverse and more structurally complex RP sites. Given the apparent non-random distribution of arthropods among the field types, my results suggest plant species composition has a significant effect on arthropod assembly. The monoculture grass stand was found to have a predator dominated arthropod community supported by a small, diverse herbivore community. It is concluded that the prairie restoration has resulted in alteration of arthropod communities supporting greater pollinator and herbivore abundance and a more balanced ratio of herbivores to predators due, in part, to increased plant structural diversity.
Elevated atherogenic index of plasma is associated with increased cardiorenal syndrome prevalence: a cross-sectional study
Creators: name: Xu, Sikai
name: Hu, Jianping
name: Ouyang, Zhiyi
name: Yuan, Maolin
name: Zheng, Yan
name: Liu, Xin
name: Shen, Yang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Cardiorenal syndrome (CRS) is a complex clinical condition characterized by the simultaneous dysfunction of the heart and kidneys. The atherogenic index of plasma (AIP), calculated as the logarithm of the ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C), has emerged as a potential biomarker for cardiovascular risk. This study investigates the association between AIP and CRS, aiming to explore the potential linkage between AIP and CRS. Data were sourced from the National Health and Nutrition Examination Survey spanning 2005–2018, involving 35,365 participants after applying exclusion criteria. The primary exposure variable was AIP, categorized into quartiles, while the primary outcome variable was CRS, defined by the coexistence of cardiovascular disease (CVD) and chronic kidney disease (CKD). Statistical analyses, considering sample weights, included ANOVA, Chi-square tests, logistic regression models, and restricted cubic spline (RCS) analysis to examine nonlinear relationships. The weighted logistic regression analysis showed a positive correlation between AIP and CRS across all models. In the fully adjusted model, the highest AIP quartile had a significantly increased odds ratio (OR) for CRS (Q4: OR = 1.62; 95% CI: 1.21–2.15). RCS analysis confirmed a positive correlation between AIP and CRS, with TG positively and HDL-C negatively correlated with CRS. Subgroup analysis indicated a significant interaction with hypertension, showing a stronger association in non-hypertensive individuals. Higher AIP levels are associated with an increased prevalence of CRS, with a notable hypertension-specific interaction indicating a higher effect in individuals without hypertension.
A STUDY ON USERS’ DISCOVERY PROCESS OF AMAZON ECHO DOT’S CAPABILITIES
Creators: name: Zhang, Lingyi
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Human-computer interaction

description: With Home Virtual Assistant (HVA) becoming popular, it has entered many families. This study aims to understand how novice users explore the capabilities of HVAs and the factors influence the users’ discovery process. The researcher used a study inspired by diary study, combining survey and interview to collect the data, along with dialogue history that contains all the activities between the user and the device. The results reveal the activities the users engage in and the factors of the HVA device and the users that influence the discovery process. Three themes emerged from the data, they are: the activities participant engaged to learn the capabilities of Echo Dot, the influence of Echo Dot being screen-less and factors of participants that influenced the initial use. Based on the results, the researcher discusses the current issues of the Echo Dot’s design and suggests potential improvement for the HVAs.
SOURCES OF HEAT REJECTION IN A HDDI DIESEL ENGINE AND METHODS TO IMPROVE THERMAL EFFICIENCY
Creators: name: Palmer, Kyle Michael
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Automotive combustion and fuel engineering

description: In the realm of class 8 trucking, fuel economy and emissions compliance are becoming the driving force for development of new heavy-duty direct injected (HDDI) diesel engine technologies. Current production engines in this class convert around 40% of the fuels energy into usable work while the unused potential transfers to the environment as excess heat energy. Current OEMs are working toward decreasing this heat loss and improve engine efficiency and emissions. Quantifying the energy lost by component and system highlights the areas that demand the most attention. By studying test cell data of heat rejection on a production Cummins ISX engine and using the data to calibrate an engine model for the simulation software GT-Suite, heat rejection values and the components which transfer the energy are exposed. The simulation software provides energy transfer by both system and component type. The results reveal that 10% of engine total heat rejection (THR) is transferred through the cylinder wall to the engine coolant system. When the heat imparted on the cylinder wall is broken up by component, the piston rings contribute nearly as much heat into the liner as the combustion gas.
Emerging insights into thyroid cancer from immunotherapy perspective: A correspondence
Creators: name: Zhang, Zheng
name: Zhang, Zhao-Nan
name: Xu, Zhen-Xi
name: Luan, Wen-Yu
name: Miao, Yan-Dong
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Biotechnology
Chemical Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer
Science Policy

description: While recent studies, such as Wang et al. have explored immunotherapy trends in thyroid cancer, methodological limitations in data retrieval persist. To address this, we implemented a refined search strategy using the Web of Science Core Collection, targeting critical fields (title, abstract, author keywords) with enhanced terminology. This approach yielded 578 publications—41% more than prior studies (e.g. 409 in Wang et al.) – demonstrating the profound impact of search precision on bibliometric outcomes. Key findings revealed a surge in publications post-2017, global collaboration patterns, and high-impact research clusters. Our study uniquely integrates bibliometric analysis with machine learning to map the evolution of thyroid cancer immunotherapy, emphasizing predictive modeling of emerging therapies and clinical translation. We further provide an open-access analytics platform to streamline data reuse, enabling researchers to identify knowledge gaps and prioritize future investigations. By enhancing methodological rigor and fostering data-driven insights, this work accelerates the translation of immunotherapy advances into clinical practice.
"Shakespeare as a Digital Nomad: An Afterword," Digital Shakespeares from the Global South, ed. Amrita Sen (New York: Palgrave, 2022), pp. 93-104.
Creators: name: Joubin, Alexa Alice
Publisher: name: Palgrave
Year: 2022
Subjects: subject: Digital humanities
subject: Postcolonialism
subject: Developing countries
subject: Shakespeare, William, 1564-1616
subject: Film adaptations

description: The rise of global Shakespeare as an industry and cultural practice—the incorporation of Shakespearean performance in cultural diplomacy and in the cultural marketplace—is aided by digital tools of dissemination and digital forms of artistic expression. Shakespeare has evolved from a cultural nomad in the past centuries—a body of works with no permanent artistic home base—to a digital nomad in the twenty-first century—an artist whose livelihood depends on commissions online and who works from any number of physical locations. The digital sphere is now the most important habitation for global Shakespeare, especially in the era of the pandemic of Covid-19. A nomad may not have a place to call home, but they can also lay claim to any cultural location.
Progress toward a novel model system to investigate fungal endophytic suppression of human pathogens in spinach
Creators: name: Golday, Justin S
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Microbiology not elsewhere classified
Plant cell and molecular biology
Animal cell and molecular biology
Mycology

description: This work describes progress toward developing a model system to investigate in plantae suppression of human pathogens by Stemphylium-like fungal endophyte strains.
Brainwave Analysis in Virtual Reality Based Emotional Regulation Training
Creators: name: Wu, Yanjun
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified
Biomechanical engineering
Digital processor architectures
Other information and computing sciences not elsewhere classified

description: Emotional regulation is how people manage their emotions especially anxiety, anger, and frustration, which are all negative emotions. It is critical to health, academic achievement, and work performance to have proper emotion regulation skills. In order to facilitate participants to manage emotions, we developed a series of training programs by using HTC© ViveTM headset and Neuracle. The HTC Vive is to improve immersion in presence to lead to more effective training, and the Neuracle is using Electroencephalography (EEG) techniques for reading user’s brainwave signals which provide real time input for the training programs. We focused on analyzing if emotion, which was reflected in brainwave signals, had changes when participants were exposed to positive/negative stimuli. The testing results indicated that there were noticeable changes in brainwave signals to stimuli. The findings from the testing provide a solid foundation to use brainwave signals as real-time input in our game development for improving emotion regulation skills in the future.
The Architecture of Childhood Vol. 1
Creators: name: Pantano, Daniele
Publisher: name: University of Lincoln
Year: 2024
Subjects: W300 - Music
W382 - Sonic arts
W390 - Music not elsewhere classified

description: Daniele Pantano’s new album of noise poems––The Architecture of Childhood (A Memoir in Noise), Vol. 1––explores his personal experiences and memories of exile, trauma, migration, immigration, refugeeism, and transitoriness. This is the first volume of Pantano’s new multi-volume memoir of noise, in which he continues to investigate the possibilities of noise as voice, poetry, and storytelling.

The Architecture of Childhood Vol. 1 | Daniele Pantano | tkbks (bandcamp.com)
PHOTOVOLTAIC SYSTEM PROPOSAL TO REDUCE KOKOMO TRANSMISSION PLANT’S ELECTRICAL DEPENDENCY
Creators: name: Turner, Troy
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Other engineering not elsewhere classified

description: Automotive manufacturers are striving to go green, while exceeding the expectations of their stakeholders. The Engineering Technology Capstone Project focused on implementing a photovoltaic (PV) system at the Kokomo Transmission Plant (KTP). The installation of a PV system will reduce KTP’s dependency on fossil fuels, while reducing their carbon footprint. The capstone project is to improve KTP’s environmental impact while reducing their electrical consumption cost in kilowatt per hour (kWh). The capstone project investigated the type of roof mounted PV system, maintenance, cost, benefits and environmental impact.
The Architecture of Childhood Vol. 1The Architecture of Childhood Vol. 1
Creators: name: Pantano, Daniele
Publisher: name: University of Lincoln
Year: 2024
Subjects: W300 - Music
W382 - Sonic arts
W390 - Music not elsewhere classified

description: Daniele Pantano’s new album of noise poems––The Architecture of Childhood (A Memoir in Noise), Vol. 1––explores his personal experiences and memories of exile, trauma, migration, immigration, refugeeism, and transitoriness. This is the first volume of Pantano’s new multi-volume memoir of noise, in which he continues to investigate the possibilities of noise as voice, poetry, and storytelling.

The Architecture of Childhood Vol. 1 | Daniele Pantano | tkbks (bandcamp.com)
Additional file 6 of A partial Drp1 knockout improves autophagy flux independent of mitochondrial function
Creators: name: Fan, Rebecca Z.
name: Sportelli, Carolina
name: Lai, Yanhao
name: Salehe, Said S.
name: Pinnell, Jennifer R.
name: Brown, Harry J.
name: Richardson, Jason R.
name: Luo, Shouqing
name: Tieu, Kim
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Supplementary Material 6: Supplementary document
Antimicrobial Resistance in Serratia marcescens
Creators: name: Sopovski, Danielle Susan
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Plant cell and molecular biology
Animal cell and molecular biology

description: With the increase of antibiotic resistant bacteria strains, the need to determine the mechanisms of antimicrobial resistance is similarly rising. Serratia marcescens, a ubiquitous, Gram-negative opportunistic pathogen is known to have strong, natural resistance to diverse antimicrobial agents including antibiotics and antimicrobial peptides. Recently, we identified S. marcescens as one of the few bacteria resistant to antimicrobial compounds produced by Stemphylium vesicarium, an isolated fungal spinach endophyte. To identify the mechanism of antimicrobial resistance to the unknown Stemphylium antimicrobial compounds, we designed a transposon mutant screen identifying mutants sensitive to antimicrobial inhibition of bacterial growth. A transposon mutant library was constructed using the Tn5 EZ-Transposome (Epicentre) system and contains 1,824 individual mutants with 127 being identified as having a decreased resistance to the Stemphylium antimicrobial compounds. The transposon growth inhibition screen initially evaluates the mutants for reduced growth in the presence of 25% fungal metabolite over 24 hours. The growth phenotype is then confirmed in triplicate in a 12-hour time course growth experiment. Identification of the genomic insertion site of the Tn5 transposon utilized a multi-step modified nested-PCR protocol, termed TAIL-PCR. Following PCR purification, nanodrop spectroscopy and gel electrophoresis were performed to ensure the amplification purity of the extracted DNA and was subsequently sequenced via WideSeq analysis. BLAST identified insertions in genes necessary for membrane biogenesis, drug transport, pili formation, and iron metabolism. Future work is aimed at confirming these results and understanding the role of iron sequestration. Not only will this research contribute to our understanding of S. marcescens antimicrobial resistance mechanisms, but it aids in our understanding of the mechanisms of antimicrobial resistance development in other human pathogens.
Evaluating the impact of the vaccination prescription program on herpes zoster vaccine coverage in Ningbo, China: An interrupted time series analysis
Creators: name: Wang, Jianmei
name: Wang, Jiaxin
name: Li, Ning
name: Du, Dongkai
name: Zhang, Dandan
name: Ma, Rui
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: As the population ages, herpes zoster (HZ) and postherpetic neuralgia, which are associated with a substantial disease burden, are expected to increase. Ningbo began to implement the Vaccination Prescription Program for community individuals in April 2022. The anonymized HZ vaccination records of individuals aged above 50 during 2020–2023 were extracted from the Ningbo Immunization Information Management System. We applied interrupted time series analyses controlling for long-term trends and seasonality to assess the effects of the program on HZ vaccination coverage. Effect modification from demographic characteristics was investigated. Totally 18,133 doses of the HZ vaccine were administered. The cumulative coverage increased from 0.16‰ to 2.97‰, and the full series cumulative coverage from 0.04‰ to 2.48‰. Relatively higher coverage and full series coverage were observed among residents, females, individuals residing in inner districts and high socioeconomic regions, and those aged 50–59 years. During the transition period, a 468.7% increase in HZ vaccination coverage was evident (Rate Ratio [RR], 5.687; 95% Confidence Interval [CI], 2.334–13.857), and significant impact was detected among all demographic characteristics. During the post-implementation period, a 261.3% increase in coverage was evident (RR, 3.613; 95% CI, 1.202–10.858), while no effect was found among migrants, individuals living in regions with high socioeconomic status, and those aged above 70 years. Although the positive effect of the program, it is imperative to implement key strategies for providing affordable HZ vaccines, such as government funding, subsidies, and vaccination prescriptions from healthcare professionals, alongside peer initiatives and family members’ education.
Deep learning for the prediction of acute kidney injury after coronary angiography and intervention in patients with chronic kidney disease: a model development and validation study
Creators: name: Tang, Ying
name: Wu, Ting
name: Wang, Xiufen
name: Wu, Xi
name: Chen, Anqun
name: Chen, Guochun
name: Tang, Chengyuan
name: He, Liyu
name: Liu, Yuting
name: Zeng, Meiyu
name: Luo, Xiaoqin
name: Duan, Shaobin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Marine Biology
Science Policy

description: Patients with chronic kidney disease (CKD) are considered the primary population at risk for post-contrast acute kidney injury (PC-AKI), yet there are few predictive tools specifically designed for this vulnerable population. Adult CKD patients undergoing coronary angiography or percutaneous coronary intervention at the Second Xiangya Hospital (2015–2021) were enrolled. The patients were divided into a derivation cohort and a validation cohort based on their admission dates. The primary outcome was the development of PC-AKI. The random forest algorithm was used to identify the most influential predictors of PC-AKI. Six machine learning algorithms were used to construct predictive models for PC-AKI. Model 1 included only preoperative variables, whereas Model 2 included both preoperative and intraoperative variables. The Mehran score was included in the comparison as a classic postoperative predictive model for PC-AKI. Among the 989 CKD patients enrolled, 125 (12.6%) developed PC-AKI. In the validation cohort, deep neural network (DNN) outperformed other machine learning models with the area under the receiver operating characteristic curve (AUROC) of 0.733 (95% CI 0.654-0.812) for Model 1 and 0.770 (95% CI 0.695-0.845) for Model 2. Furthermore, Model 2 showed better performance compared to the Mehran score (AUROC 0.631, 95% CI 0.538-0.724). The SHapley Additive exPlanations method provided interpretability for the DNN models. A web-based tool was established to help clinicians stratify the risk of PC-AKI (https://xydsbakigroup.streamlit.app/). The explainable DNN models serve as promising tools for predicting PC-AKI in CKD patients undergoing coronary angiography and intervention, which is crucial for risk stratification and clinical descion-making.
Additional file 1 of Errors in visual search: Are they stochastic or deterministic?
Creators: name: Li, Aoqi
name: Hulleman, Johan
name: Wolfe, Jeremy M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file1. Detailed Model Illustration and RT analyses.
Ablaze: The 1849 White Supremacist Attack on the Pendleton Post Office
Creators: name: Ashton, Susanna Margaret
Publisher: name: Humanities Commons
Year: 2022
Subjects: subject: Slavery
subject: South Carolina

description: In 1849, a mob of white supremacists eager to seize anti-slavery mailings attacked the US Post Office in Pendleton, South Carolina. They burned leaflets and letters in a bonfire on the village green to make clear their stance against incendiary ideas. This essay explores the context of these events by considering an initial spate of mailings that happened in 1835. This examination includes their author, William Brisbane; the Calhounist culture of Pendleton that fueled this demonstration; the sad fate of the young man, John Barrett, who was arrested for the distribution of such materials; and those held captive in the middle of it all, the enslaved African Americans of Pendleton.
Additional file 1 of The cost of illness and burden of suicide and suicide attempts in France
Creators: name: Segar, Laeticia Blampain
name: Laidi, Charles
name: Godin, Ophélia
name: Courtet, Philippe
name: Vaiva, Guillaume
name: Leboyer, Marion
name: Durand-Zaleski, Isabelle
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cancer
Science Policy

description: Supplementary Material 1.
Effect of Parental Care on the Verical Transmission of Enteric Bacteria in  Nicrophorus Defodiens
Creators: name: Miller, Christopher
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Animal behaviour
Microbial ecology

description: Parental care has evolved promote fitness gains. Burying beetles engage in extensive pre- hatching and post-hatching parental care providing several avenues to transmit bacteria to their offspring. One aspect of pre-hatching parental care consists of preserving a small vertebrate carcass via oral and anal secretions, allowing the carcass to be used as a reproductive resource. Post-hatching parental care consists in large part of parental regurgitations of the preserved carcass. We sought to determine if pre-hatching parental care resulted in bacterial transmission from adults to carcasses via anal secretions. We then sought to determine if lab-rearing conditions affected the digestive tract bacterial communities of F1 and F2 generation adults. We finally sought to determine if carcasses and post-hatching parental care in the form of parental regurgitations resulted into bacterial transmission to larvae. Using High-Throughput Illumina MiSeq, we were able to characterize bacterial communities of adult and larval digestive tracts, anal secretions, and unprepared and prepared carcasses. Our results show that bacterial communities of adults are dissimilar from anal secretions and prepared carcasses. We then show that lab-rearing conditions do not significantly alter digestive tract bacterial communities of F1 and F2 generation adults relative to wild caught adults. We proceed to show that larvae receiving parental regurgitations have digestive tract bacterial communities similar to their parents whereas larvae that do not receive parental regurgitations have dissimilar digestive tract bacterial communities from their parents. We further show that bacterial communities of prepared carcasses are dissimilar from all larvae. Our evidence suggests that anal secretions to preserve carcasses for the reproductive bout and have no influence on bacterial transmission to neither carcasses nor larvae. Our evidence also suggests that parental regurgitations influence bacterial transmission to offspring.
Drogenkonsum: Bacillus anthracis in Heroin?
Creators: name: Bernard, Helen
name: Faber, Mirko
name: Grunow, Roland
name: Bochat, Verena
name: Görg, Anette
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Infektionsrisiko
subject: Milzbrand
subject: Drogenmissbrauch
subject: Robert-Koch-Institut
subject: 610 Medizin

description: Das Robert-Koch-Institut bittet die Ärzteschaft um erhöhte Aufmerksamkeit bezüglich Haut- oder Weichteilinfektionen bei Heroinkonsumenten, da diese durch den Milzbranderreger verursacht sein könnten.
Aortoenterik Fistül Olgusuna Sistematik Cerrahi Yaklaşım
Creators: name: TÜYSÜZ, Mehmet Erin
Publisher: name: Zenodo
Year: 2025

description: Aortoenterik fistül (AEF), vasküler cerrahide en zorlu tanı ve tedavi edici durumlardan biridir. AEF, primer olarak aort ve gastrointestinal sisteminde veya daha yaygın olarak önceki aort rekonstrüktif cerrahisine sekonder olarak ortaya çıkabilir.Bizim olgumuzda daha öncesinde rüptüre abdominal aort anevrizması olması nedeniyle tarafımızca opere edilip sonrasında AEF oluşması nedeniyle sistemik cerrahi yaklaşım planladık.