cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sup norms of Cauchy data of eigenfunctions on manifolds with concave boundary
Creators: name: Sogge, C. D.
name: Zelditch, S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We prove that the Cauchy data of Dirichlet or Neumann $Δ$- eigenfunctions of Riemannian manifolds with concave (diffractive) boundary can only achieve maximal sup norm bounds if there exists a self-focal point on the boundary, i.e. a point at which a positive measure of geodesics leaving the point return to the point. As an application, the Dirichlet or Neumann eigenfunctions of Riemannian manifolds with concave boundary and non-positive curvature never have eigenfunctions whose boundary traces achieve maximal sup norm bounds.
description: This result is used in the article arXiv:1401.4520 of the second author with J.Jung on counting nodal domains on surfaces of non-positive curvature and concave boundary
BAB 2 Akuntansi Untuk Pendirian Firma Pertemuan 3 19 September 2022
Creators: name: Dr. Rusdiyanto, SE,. M. Ak,. CH,. CHt
Publisher: name: Zenodo
Year: 2022
Subjects: BAB 2, Akuntansi, Pendirian Firma, AKL1

description: Akuntansi Pendirian Firma/Persekutuan
 Firma adalah merupakan bentuk perusahaan yang didirikan oleh dua orang atau lebih untuk memperluas usahanya atau
 untuk memperoleh laba. Tujuan pendirian firma ini biasanya adalah untuk memperluas usaha & menambah modal agar lebih kuat &
 mampu bersaing dengan perusahaan-perusahaan yang lain. Firma biasanya disebut juga Persekutuan (Partnership), dengan demikian pemilik Firma disebut dengan anggota atau sekutu atau partner. Di dalam firma semua anggota atau sekutu adalah pemilik yang sekaligus merangkap pengelola (manajemen) yang secara langsung aktif melaksanakan usaha perusahaan.
БЕЗОПАСНОСТЬ В СФЕРЕ ЭКОНОМИЧЕСКОЙ ДЕЯТЕЛЬНОСТИ КАК ПРАВОВАЯ КАТЕГОРИЯ И ОБЪЕКТ УГОЛОВНОПРАВОВОЙ ОХРАНЫ
Creators: name: Майстренко Г.А.
Publisher: name: Образование и право
Year: 2022
Subjects: экономическая безопасность
экономическая преступность
противодействие
рыночная система хозяйствования
стабильность финансово-экономической системы.

description: Статья посвящена научно-практическим и правовым проблемам определения экономической безопасности как особого объекта уголовно-правовой охраны. Автором на основе анализа мнений представителей научного сообщества определены основные критерии и свойства названной категории, имеющие значение для противодействия экономической преступности в целом.
Inference on Nonstationary Time Series with Moving Mean
Creators: name: Gao, Jiti
name: Robinson, Peter M.
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: A semiparametric model is proposed in which a parametric filtering of a non-stationary time series, incorporating fractionally differencing with short memory correction, removes correlation but leaves a nonparametric deterministic trend. Estimates of the memory parameter and other dependence parameters are proposed, and shown to be consistent and asymptotically normally distributed with parametric rate. Unit root tests with standard asymptotics are thereby justified. Estimation of the trend function is also considered. We include a Monte Carlo study of finite-sample performance.
Genetic Interference: Dont Stand So Close to Me
Creators: name: Berchowitz, Luke
name: Copenhaver, Gregory
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Meiosis is a dynamic process during which chromosomes undergo condensation, pairing, crossing-over and disjunction. Stringent regulation of the distribution and quantity of meiotic crossovers is critical for proper chromosome segregation in many organisms. In humans, aberrant crossover placement and the failure to faithfully segregate meiotic chromosomes often results in severe genetic disorders such as Down syndrome and Edwards syndrome. In most sexually reproducing organisms, crossovers are more evenly spaced than would be expected from a random distribution. This phenomenon, termed interference, was first reported in the early 20th century by Drosophila geneticists and has been subsequently observed in a vast range of organisms from yeasts to humans. Yet, many questions regarding the behavior and mechanism of interference remain poorly understood. In this review, we examine results new and old, from a wide range of organisms, to begin to understand the progress and remaining challenges to understanding the fundamental unanswered questions regarding genetic interference.
ВОПРОСЫ СОДЕРЖАНИЯ ОБУЧЕНИЯ КУРСАНТОВ ПЕНИТЕНЦИАРНЫХ ОБРАЗОВАТЕЛЬНЫХ УЧРЕЖДЕНИЙ РАБОТЕ ПО ИЗУЧЕНИЮ СОЦИАЛЬНО-ПСИХОЛОГИЧЕСКОГО КЛИМАТА В КОЛЛЕКТИВАХ СОТРУДНИКОВ
Creators: name: Казберов П.Н.
Publisher: name: Образование и право
Year: 2022
Subjects: курсанты
обучение
изучение
формирование
социально-психологический климат
сотрудники
стресс
определение.

description: Служебная деятельность пенитенциарных сотрудниковвсегда объективно носила во многом экстремальный и, следовательно, психогенный характер. Логическим следствием такой профессиональной деятельности являются не только негативные личностные изменения, происходящие с отдельно взятым сотрудником, но и деструктивные процессы и явления, носящие групповой характер. Качественное и своевременной обучение курсантов ведомственных ВУЗов пенитенциарной системы умению не только изучать, но и формировать, поддерживать конструктивный социально-психологический климат в коллективах сотрудников ФСИН России – это во многом залог успешности будущего психолога подразделения. Практика обучения курсантов ведомственных ВУЗов пенитенциарной системы определяет на ряду с трудностями организационного и субъективного характера, наличие трудностей в обучении курсантов вполне объективного характера. Раскрытие вопроса основных характеристик (составляющих) такого явления как социально-психологический климат в коллективах сотрудников определяет предмет и возможные способы (методы) их изучения, а соответственно и обучения этому будущих психологов. Сложности объяснения курсантам такого направления их будущей профессиональной деятельности, как изучение социально-психологического климата начинаются на теоретическом уровне. Многочисленные исследователи этого вопроса используют весьма различные категории, термины, характеризуя рассматриваемое явление. Не меньше проблемных вопросов и в прикладном аспекте изучения, формирования и поддержания конструктивного социально-психологического климата в коллективах сотрудников. этнические группы, психологи, воспитатели.
Dolostone as a reliable tracer of seawater lithium isotope composition
Creators: name: Zhai S.
name: Liu X.-M.
name: Liu X.-F.
name: Liu X.
name: Wang X.-K.
Publisher: name: Nature Publishing Group
Year: 2023

description: The lithium isotope composition (δ7Li) of seawater records important information on the evolution of the carbon and silicon cycles over geologic time. Here we report δ7Li values in a suite of Neogene dolostones (23–3.4 Ma, n = 39) from the South China Sea. Over the Neogene, dolostone δ7Li values have increased from 24.9‰ to 30.1‰, overlapping previously published foraminifera records and documenting seawater δ7Li without applying any isotopic fractionation factor correction. Our results suggest that fabric-retentive dolostones are good proxies for providing seawater δ7Li records even after early diagenesis. Importantly, these results provide a high-resolution dolostone record rather than a foraminifera record to confirm the observed ~5‰ increase in Neogene seawater δ7Li. We predict that early marine diagenetic dolostones with fabric textures abundant in the Proterozoic may record changes in seawater δ7Li and continental weathering, providing great insights into the Precambrian global carbon cycle.
Illuminating microRNA Transcription from the Epigenome
Creators: name: Sethupathy, Praveen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Cellular gene expression is governed by a complex, multi-faceted network of regulatory interactions. In the last decade, microRNAs (miRNAs) have emerged as critical components of this network. miRNAs are small, non-coding RNA molecules that serve as post-transcriptional regulators of gene expression. Although there has been substantive progress in our understanding of miRNA-mediated gene regulation, the mechanisms that control the expression of the miRNAs themselves are less well understood. Identifying the factors that control miRNA expression will be critical for further characterizing miRNA function in normal physiology and pathobiology. We describe recent progress in the efforts to map genomic regions that control miRNA transcription (such as promoters). In particular, we highlight the utility of large-scale “-omic” data, such as those made available by the ENCODE and the NIH Roadmap Epigenomics consortiums, for the discovery of transcriptional control elements that govern miRNA expression. Finally, we discuss how integrative analysis of complementary genetic datasets, such as the NHGRI Genome Wide Association Studies Catalog, can predict novel roles for transcriptional mis-regulation of miRNAs in complex disease etiology.
title: Pathomechanisms of Synkinesis- A Scoping Review
Creators: name: Lawrence, Amelia
name: Johnson, Peter
name: Dr. John Flynn
name: Nieves, Antonio Bon
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Medicine and Health Sciences

description: The primary goal of this scoping review is to comprehensively organize and synthesize the existing body of literature concerning synkinesis mechanism and pathophysiology. We aim to systematically map the research done on the mechanism of synkinesis with hopes to determine potential gaps in the literature, which mechanisms are most studied, and potential for future research. This scoping review will additionally explore synkinesis definitions and the published literature surrounding potential causative factors and etiologies contributing to synkinesis.
Contextualizing the Genes Altered in Bladder Neoplasms in Pediatric and Teen Patients Allows Identifying Two Main Classes of Biological Processes Involved and New Potential Therapeutic Targets
Creators: name: Piergentili, R.
name: Porrello, A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Research on bladder neoplasms in pediatric and teen patients (BNPTP) has described 21 genes, which are variously involved in this disease and are mostly responsible for deregulated cell proliferation. However, due to the limited number of publications on this subject, it is still unclear what type of relationships there are among these genes and which are the chances that, while having different molecular functions, they i) act as downstream effector genes of well-known pro- or anti- proliferative stimuli and/or interplay with biochemical pathways having oncological relevance or ii) are specific and, possibly, early biomarkers of these pathologies. A Gene Ontology (GO)-based analysis showed that these 21 genes are involved in biological processes, which can be split into two main classes: cell regulation-based and differentiation/development-based. In order to understand the involvement/overlapping with main cancer-related pathways, we performed a meta-analysis dependent on the 189 oncogenic signatures of the Molecular Signatures Database (OSMSD) curated by the Broad Institute. We generated a binary matrix with 53 gene signatures having at least one hit; this analysis i) suggests that some genes of the original list show inconsistencies and might need to be experimentally re- assessed or evaluated as biomarkers (in particular, ACTA2) and ii) allows hypothesizing that important (proto)oncogenes (E2F3, ERBB2/HER2, CCND1, WNT1, and YAP1) and (putative) tumor suppressors (BRCA1, RBBP8/CTIP, and RB1-RBL2/p130) may participate in the onset of this disease or worsen the observed phenotype, thus expanding the list of possible molecular targets for the treatment of BNPTP.
ВОПРОСЫ ПРАВОВОГО РЕГУЛИРОВАНИЯ ФИНАНСОВОГО КОНТРОЛЯ В ГОРОДЕ МОСКВЕ
Creators: name: Афанасьева С.А.
Publisher: name: Образование и право
Year: 2022
Subjects: финансовый контроль
бюджетные средства
Контрольно-счетная палата Москвы
контрольно-надзорные органы
финансовый аудит.

description: В представленной статье автор анализирует некоторые вопросы правового регулирования финансового контроля в городе Москве, эффективность его осуществления органами власти столицы. Кроме того, анализируются отдельные полномочия органов внешнего и внутреннего финансового контроля в городе Москве, положения московского законодательства в этой части. Автор путем анализа норм законодательства и практики его применения в городе Москве делает вывод о его несовершенстве в части регулирования финансового контроля, в том числе взаимодействия субъектов контроля при его реализации на территории столицы, предпринимает попытку определить основные направления дальнейшего развития законодательства в этой части.
Population statistics of beamed sources. II: Evaluation of Doppler factor estimates
Creators: name: Liodakis, I.
name: Pavlidou, V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In a companion paper we presented a statistical model for the blazar population, consisting of distributions for the unbeamed radio luminosity function and the Lorentz factor distribution of each of the BL Lac and Flat Spectrum Radio Quasar (FSRQ) classes. Our model has been optimized so that it reproduces the MOJAVE distributions of apparent speeds and redshifts when the appropriate flux limit is applied and a uniform distribution of jet viewing angles is assumed for the population. Here we use this model to predict the Doppler factor distribution for various flux-limited samples for which Doppler factors have been estimated in a variety of ways (equipartition, variability + equipartition, inverse Compton dominance) on a blazar-by-blazar basis. By comparing the simulated and data-estimated Doppler factor distributions in each case, we evaluate the different methods of estimating blazar Doppler factors. We find that the variability Doppler factors assuming equipartition are the ones in the best agreement with our statistical model, whereas the inverse Compton Doppler factor method is only suitable for FSRQs. In the case of variability Doppler factors, we find that while random errors are relatively low ($\sim 30\%$), uncertainties are dominated by systematic effects. In the case of inverse Compton Doppler factors, random errors appear to dominate, but are significantly larger ($\sim 60\%$).
description: 11 pages, 17 figures, published in MNRAS
Functional Coefficient Nonstationary Regression with Non- and Semi-Parametric Cointegration
Creators: name: Gao, Jiti
name: Phillips, Peter C.B.
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: This paper studies a general class of nonlinear varying coefficient time series models with possible nonstationarity in both the regressors and the varying coefficient components. The model accommodates a cointegrating structure and allows for endo-geneity with contemporaneous correlation among the regressors, the varying coefficient drivers, and the residuals. This framework allows for a mixture of stationary and non-stationary data and is well suited to a variety of models that are commonly used in applied econometric work. Nonparametric and semiparametric estimation methods are proposed to estimate the varying coefficient functions. The analytical findings reveal some important differences, including convergence rates, that can arise in the conduct of semiparametric regression with nonstationary data. The results include some new asymptotic theory for nonlinear functionals of nonstationary and stationary time series that are of wider interest and applicability and subsume much earlier research on such systems. The finite sample properties of the proposed econometric methods are analyzed in simulations. An empirical illustration examines nonlinear dependencies in aggregate consumption function behavior in the US over the period 1960 - 2009.
Social Media and the Practicing Hematologist: Twitter 101 for the Busy Healthcare Provider
Creators: name: Wood, William A.
name: Thompson, Michael A.
name: Chaboissier, Mélanie
name: Majhail, Navneet S.
name: Perales, Miguel-Angel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Social media is a relatively new form of media that includes social networks for communication dissemination and interaction. Patients, physicians, and other users are active on social media including the microblogging platform Twitter. Many online resources are available to facilitate joining and adding to online conversations. Social media can be used for professional uses, therefore we include anecdotes of physicians starting on and implementing social media successfully despite the limits of time in busy practices. Various applications demonstrating the utility of social media are explored. These include case discussions, patient groups, research collaborations, medical education and crowdsourcing/crowdfunding. Social media is integrating into the professional workflow for some individuals and hematology/oncology societies. The potential for improving hematology care and research is just starting to be explored.
ЗАКОНОДАТЕЛЬНОЕ РЕГУЛИРОВАНИЕ ГОСУДАРСТВЕННОЙ ПОДДЕРЖКИ ИНСТИТУТОВ ГРАЖДАНСКОГО ОБЩЕСТВА: СОСТОЯНИЕ И ПЕРСПЕКТИВЫ РАЗВИТИЯ
Creators: name: Никитина Е.Е.
Publisher: name: Образование и право
Year: 2022
Subjects: гражданское общество
институты гражданского общества
органы публичной власти
государственная поддержка
грант.

description: Статья посвящена конституционно-правовому анализу федерального компонента в системе действующего законодательства, регулирующего государственную поддержку институтов гражданского общества в Российской Федерации. Актуальность исследования обусловлена происходящей социальной трансформацией, которая характеризуется качественными изменениями самой структуры общества, усложнением общественных связей, принципиальным ускорением коммуникации и усилением информационного воздействия на общество. Данные изменения во многом привели к включению в Конституцию Российской Федерации положений, связанных с взаимодействием государства и гражданского общества. В работе проанализированы конституционные положения и сделан вывод о закреплении в ее тексте двух способов осуществления государственной поддержки: институциональная поддержка (поддержка институтов гражданского общества) функциональная поддержка (поддержка деятельности, которую осуществляют институты гражданского общества). Автором обращено внимание на проблемы действующего федерального законодательства в указанной сфере и предлагаются пути его совершенствования: необходимость переноса существенной части нормативных правил распределения государственной финансовой поддержки с подзаконного уровня на уровень федерального закона, выработка единой терминологии, закрепление общих стандартов к критериям организаций, которым может быть предоставлена государственная помощь. Автор полагает, что постоянно меняющиеся правила распределения государственной поддержки не позволяют институтам гражданского общества выработать собственную стратегию развития. Предложенные в статье меры будут способствовать укреплению доверия между органами публичной власти, гражданами и их объединениями.
Exploring Devolved Decision Authority in Performance Management Regimes: The Relevance of Perceived and Actual Decision Authority as Elements of Performance Management Success
Creators: name: Roenigk D.J.
name: Ammons D.N.
Publisher: name: Routledge
Year: 2020

description: According to performance management doctrine, successful performance management requires devolved decision authority—that is, meaningful decision authority must be placed in the hands of managers at the program level, where those best equipped with insights can make needed changes. Using both perceptual and objective information on decision authority in 62 select U.S. city and county governments, the authors find a positive relationship between devolved decision authority and reported performance management success—especially when managers both have and perceive that they have meaningful discretion.
ЗАКОНОДАТЕЛЬНОЕ РЕГУЛИРОВАНИЕ УЧАСТИЯ В ГРАЖДАНСКОПРАВОВЫХ СДЕЛКАХ ГРАЖДАН, СОДЕРЖАЩИХСЯ В МЕСТАХ СОДЕРЖАНИЯ ПОД СТРАЖЕЙ
Creators: name: Новицкий С.С.
name: Новицкая Л.Ю.
Publisher: name: Образование и право
Year: 2022
Subjects: гражданско-правовые сделки
гражданское законодательство
содержание под стражей
права граждан
нотариус.

description: В статье проводится анализ норм гражданского и уголовно-процессуального законодательства, регламентирующих права лиц, содержащихся под стражей, на участие в гражданско-правовых сделках. Рассматриваются понятия, отнесенные нормативными правовыми актами к указанному виду сделок. На основе проведенного анализа делаются предложения по внесению изменений в действующее законодательство Российской Федерации.
ЗАЩИТА ПРАВ НЕСОВЕРШЕННОЛЕТНИХ ОСУЖДЕННЫХ, ОТБЫВАЮЩИХ НАКАЗАНИЕ В ВИДЕ ЛИШЕНИЯ СВОБОДЫ: ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ
Creators: name: Майстренко Г.А.
Publisher: name: Образование и право
Year: 2022
Subjects: право
несовершеннолетний осужденный
воспитательная колония
закон
государственная власть
защита
самозащита.

description: В статье автором сделана попытка раскрыть часть проблем защиты прав несовершеннолетних осужденных отбывающих наказания в виде лишения свободы. Вопросы защиты прав несовершеннолетних осужденных постоянно находится во внимании общества, общественных организаций, государственной власти, но на ряду с положительными аспектами имеются ряд проблем, которые автором частично показаны в представленной статье. Основной проблемой в данном вопросе раскрывается сам субъект правоотношений – несовершеннолетний осужденный, затрудняющем самостоятельную защиту прав, в силу недостаточного уровня знаний, юридической грамотности, как для осознания факта нарушения собственных прав, так и для соблюдения процедур по их защите, психологической устойчивости и готовности к отстаиванию собственных интересов.
title: Geometries of Tall Buildings Improving Wind Comfort in London
Creators: name: Kim, Yujin
Publisher: name: The Open University
Year: 2023

description: The objective of the present study is to improve pedestrian-level wind (PLW) comfort by developing design procedures for tall buildings in London. While tall buildings address London’s increasing urban population and rising land prices, they introduce several wind microclimatic challenges, accelerating PLWs causing PLW discomfort and safety concerns. Previous research that has focused primarily on perpendicular façades has limitations for assessing the aerodynamic performances of London’s tall buildings, which have various façade angles. Extant studies using urban packing densities (plan area ratio [PAR], frontal area ratio [FAR] and façade area ratio [FAR′]) have gaps when examining the impacts of urban forms on PLWs in cases where two different urban typologies have similar PAR, FAR and FAR′. To advance knowledge regarding the aerodynamic performance of various building geometries, the analytical and simulation work was undertaken, using computational fluid dynamics (CFD) as the main methodology. A sensitivity study and field measurements were carried out to verify and validate the accuracy of the CFD results. A comparative analysis was undertaken between the isolated building condition (pure aerodynamic condition without impacts from the surrounding buildings) and London’s typical urban conditions to examine the aerodynamic interactions between the tall building and the surrounding buildings. The results suggest that wind comfort assessments of tall buildings should be undertaken in an urban context, as significantly different results were obtained between the isolated and urban conditions. The building parameters – façade angle, corner condition and height – and the urban parameter – open area ratio [OAR] – should all be considered when assessing the effects of tall buildings on PLW comfort in urban environments. The design guidelines, based on the new knowledge discovered by the current study, provide recommendations concerning the urban-related and building geometry-related design requirements.
Current Interventions to Reduce Sexual Risk Behaviors and Crack Cocaine Use among HIV-Infected Individuals
Creators: name: El-Bassel, Nabila
name: Golin, Carol
name: Hopkins, Jessica
name: Wechsberg, Wendee M.
name: Zule, William
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The dual global epidemics of crack cocaine use and HIV have resulted in a large number of people living with HIV who use crack cocaine, many of whom continue to engage in unprotected sex. Crack use also increases the rate of HIV progression. Consequently, there is an urgent need for effective interventions to decrease crack use and unprotected sex and to improve antiretroviral therapy (ART) adherence in this population. This article reviews the recent published literature on interventions for reducing crack use and unprotected sex among people living with HIV. Only a few intervention outcome studies targeting exclusively HIV positive crack cocaine users were identified, whereas other studies used a mixed sample. Some interventions focused on reducing crack use and several focused on reducing sex-risk behaviors. Consequently, there is a critical need for efficacious interventions that address crack use, risky sex and ART adherence among people living with HIV.
Neutron stars in Einstein-$Λ$ gravity: the cosmological constant effects
Creators: name: Bordbar, G. H.
name: Hendi, S. H.
name: Panah, B. Eslam
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Regarding a $d-$dimensional spherically symmetric line element in the context of Einstein-$Λ$ gravity, the hydrostatic equilibrium equation of stars is obtained. Then, by using the lowest order constrained variational (LOCV) method with the AV$18$ potential and employing microscopic many body calculations in the modern equation of state, the structure properties of neutron stars are investigated. Regardless of cosmological point of view and considering arbitrary positive and negative values of the cosmological constant, the maximum mass of the neutron stars and their corresponding radius in $4$-dimensions are computed. The results show that there is an upper limit for the maximum mass of neutron star for positive cosmological constant ($M_{\max }\leq 1.68M_{\odot }$). On the other hand, it is shown that the Einstein gravity cannot explain the structure of neutron star with negative $Λ$. Other properties of neutron stars such as; the Schwarzschild radius, average density, compactness and Buchdahl- Bondi bound are studied. In addition, by using the Buchdahl-Bondi bound for neutron stars, stability of these stars is investigated. Finally, the dynamical stability is investigated and shown that the neutron stars follow the dynamical stability in this gravity.
description: 14 pages, 10 figures, title changed, numerical solutions added, references added
The HIV-1 Env Protein: A Coat of Many Colors
Creators: name: Joseph, Sarah Beth
name: Arrildt, Kathryn Twigg
name: Swanstrom, Ronald
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Human immunodeficiency virus type 1 (HIV-1) is completely dependent upon the Env protein to enter cells. The virus typically replicates in activated CD4+ T cells due to viral entry requirements for the CCR5 coreceptor and for high surface levels of the CD4 receptor. This is the case for the transmitted virus and for most of the virus sampled in the blood. Over the course of infection, the env gene can evolve to encode a protein with altered receptor and coreceptor usage allowing the virus to enter alternative host cells. In about 50% of HIV-1 infections, the viral population undergoes coreceptor switching, usually late in disease, allowing the virus to use CXCR4 to enter a different subset of CD4+ T cells. Neurocognitive disorders occur in about 10% of infections, also usually late in disease, but caused (ultimately) by viral replication in the brain either in CD4+ T cells or macrophage and/or microglia. Expanded host range is significantly intertwined with pathogenesis. Identification and characterization of such HIV-1 variants may be useful for early detection which would allow intervention to reduce viral pathogenesis in these alternative cell types.
ЗЛОУПОТРЕБЛЕНИЕ ПОТРЕБИТЕЛЕМ ПРАВАМИ НА ЗАЩИТУ (ПОТРЕБИТЕЛЬСКИЙ ЭКСТРЕМИЗМ)
Creators: name: Поснов И.В.
name: Темботов Р.А.
Publisher: name: Образование и право
Year: 2022
Subjects: гражданское право
гражданский процесс
судебная система
право на защиту
злоупотребление правом.

description: Авторы рассматривают проблемы злоупотребления прав потребителем на защиту в ключе теоретических научных исследований, руководящих разъяснений вышестоящих судебных инстанций, функционирования судебного механизма в целом. Эффективное использование в практической деятельности норм права судами есть нормальное обеспечения функционирования и развития различных социальных сфер жизни общества в целом. Проблемы обуславливающие актуальность: активизация деловой активности юридических и физических лиц в период отмены ковидных ограничений, необходимость качественной работы по реализации, развитию и совершенствованию законодательства, организации корректного применения законодательства потребителями и реализаторами услуг. В статье рассматриваются проблемы отечественного теоретического исследования проблемы злоупотребления правом потребителями, опыт правоприменения.
Hermite Series Estimation in Nonlinear Cointegrating Models
Creators: name: Cai, Biqing
name: Gao, Jiti
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: This paper discusses nonparametric series estimation of integrable cointegration models using Hermite functions. We establish the uniform consistency and asymptotic normality of the series estimator. The Monte Carlo simulation results show that the performance of the estimator is numerically satisfactory. We then apply the estimator to estimate the stock return predictive function. The out-of-sample evaluation results suggest that dividend yield has nonlinear predictive power for stock returns while book-to-market ratio and earning-price ratio have little predictive power.
Antiretroviral Drug Regimens to Prevent Mother-To-Child Transmission of HIV: A Review of Scientific, Program, and Policy Advances for Sub-Saharan Africa
Creators: name: Moodley, Dhayendre
name: Stringer, Jeffrey S. A.
name: Chi, Benjamin H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Considerable advances have been made in the effort to prevent mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. Clinical trials have demonstrated the efficacy of antiretroviral regimens to interrupt HIV transmission through the antenatal, intrapartum, and postnatal periods. Scientific discoveries have been rapidly translated into health policy, bolstered by substantial investment in health infrastructure capable of delivering increasingly complex services. A new scientific agenda is also emerging, one that is focused on the challenges of effective and sustainable program implementation. Finally, global campaigns to “virtually eliminate” pediatric HIV and dramatically reduce HIV-related maternal mortality have mobilized new resources and renewed political will. Each of these developments marks a major step in regional PMTCT efforts; their convergence signals a time of rapid progress in the field, characterized by an increased interdependency between clinical research, program implementation, and policy. In this review, we take stock of recent advances across each of these areas, highlighting the challenges – and opportunities – of improving health services for HIV-infected mothers and their children across the region.
Éditorial
Creators: name: Le Quellec Cottier, Christine
name: Leroy, Claude
Publisher: name: Classiques Garnier
Year: 2022
Subjects: subject: AIBC
subject: CEBC
subject: Relance
subject: Séminaire
subject: Thèses
subject: Éditions
subject: Gallimard
subject: Denoël.
subject: AIBC
subject: CEBC
subject: Resumption
subject: Seminar
subject: Thesis
subject: Edition
subject: Gallimard
subject: Denoël.

description: Surmontant les difficultés sanitaires et les obstacles juridiques, la vie de nos associations a repris un cours régulier : rencontre annuelle du CEBC à Berne, reprise du séminaire de l’AIBC à Paris, parution de notre revue commune. Contribuent à la relance des activités autour de Cendrars des rencontres, des conférences, des spectacles, les thèses universitaires de jeunes chercheurs et de nouvelles publications annoncées chez Gallimard et Denoël.
description: Overcoming sanitary difficulties and legal obstacles, associational life resumed on a regular basis: annual encounter of the CEBC in Berne, resumption of the AIBC seminar in Paris, publication of our common review. Contributed in the revival of activities concerning Cendrars, encounters, lectures, shows, academic thesis of young researchers and new publications announced at Gallimard and Denoël.
Advances in HIV Prevention for Serodiscordant Couples
Creators: name: Cohen, Myron S.
name: Muessig, Kathryn E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Serodiscordant couples play an important role in maintaining the global HIV epidemic. This review summarizes biobehavioral and biomedical HIV prevention options for serodiscordant couples focusing on advances in 2013 and 2014, including World Health Organization guidelines and best-evidence for couples counseling, couples-based interventions, and the use of antiviral agents for prevention. In the past few years marked advances have been made in HIV prevention for serodiscordant couples and numerous ongoing studies are continuously expanding HIV prevention tools, especially in the area of pre-exposure prophylaxis. Uptake and adherence to antiviral therapy remains a key challenge. Additional research is needed to develop evidence-based interventions for couples, and especially for male-male couples. Randomized trials have demonstrated the prevention benefits of antiretroviral-based approaches among serodiscordant couples; however, residual transmission observed in recognized serodiscordant couples represents an important and resolvable challenge in HIV prevention.
A STEMM woman's guide to leadership characteristics and management skills
Creators: name: Maurice, Patricia A.
name: Hering, Janet G.
Publisher: name: Zenodo
Year: 2024
Subjects: subject: leadership
subject: Gender equality

description: This is a copy of a blog posted on the Epistimi website at: https://www.epistimi.org/blog/a-stemm-womans-guide-to-leadership-characteristics-and-management-skills
Global Classical Solutions of the one and one-half dimensional Vlasov-Maxwell Fokker-Planck System
Creators: name: Pankavich, Stephen
name: Schaeffer, Jack
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We study the "one and one-half" dimensional Vlasov-Maxwell-Fokker-Planck system and obtain the first results concerning well-posedness of solutions. Specifically, we prove the global-in-time existence and uniqueness in the large of classical solutions to the Cauchy problem and a gain in regularity of the distribution function in its momentum argument.
description: 28 pages. arXiv admin note: text overlap with arXiv:1312.3666
A Systematic Review of Recent Smartphone, Internet and Web 2.0 Interventions to Address the HIV Continuum of Care
Creators: name: Hightow-Weidman, Lisa B.
name: Bauermeister, Jose
name: Bull, Sheana
name: Nekkanti, Manali
name: Muessig, Kathryn E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: eHealth, mHealth and “Web 2.0” social media strategies can effectively reach and engage key populations in HIV prevention across the testing, treatment, and care continuum. To assess how these tools are currently being used within the field of HIV prevention and care, we systematically reviewed recent (2013–2014) published literature, conference abstracts, and funded research. Our searches identified 23 published intervention studies and 32 funded projects underway. In this synthesis we describe the technology modes applied and the stages of the HIV care cascade addressed, including both primary and secondary prevention activities. Overall trends include use of new tools including social networking sites, provision of real-time assessment and feedback, gamification and virtual reality. While there has been increasing attention to use of technology to address the care continuum, gaps remain around linkage to care, retention in care, and initiation of antiretroviral therapy.
ИЗ ИСТОРИИ ОРГАНИЗАЦИИ ТЮРЕМНЫХ УЧРЕЖДЕНИИ НА ТЕРРИТОРИИ ОРЕНБУРГСКОЙ ГУБЕРНИИ В XVIII-XIX ВЕКАХ
Creators: name: Евсеев И.В.
name: Слукин С.В.
Publisher: name: Образование и право
Year: 2022
Subjects: гауптвахты
углы
чуланы
тюрьмы
главное тюремное управление
исправительные учреждения
тюремная система
исправительно трудовая система.

description: В статье обобщается исторический материал развития тюремных учреждении на территории Урала в период XVIII-XIX веков, когда из множества отдельных и не связанных друг с другом тюрем разной подчинённости направленности была выстроена целостная тюремная система. Так, на Урале были построены новые тюрьмы в Челябинске, Троицке, Златоусте, Верхнеуральске, Орске, Магнитной и других городах Оренбургской губернии. К началу ХХ века в Оренбургской губернии, как и в других губерниях Урала, уже четко вырисовывалась схема подчиненности и размещения учреждении тюремного вида по губернии с четкой привязанности тюрем к промышленным площадкам. Главным становился вопрос индустриального освоения края, где огромная роль отводилась контингенту тюремной системы и самой тюремной системе. Построенные тюрьмы конца ХIХ и начала ХХ века стали опорными пунктами. Все учреждения были разбиты по кустовой принадлежности по всему Уралу. Именно на этой кустовой основе в дальнейшем и сформировались учреждения современной системы. Исходя из рационалистического подхода, создание и функционирование специального учреждения изоляции должно было соответствовать долговременным или сиюминутным целям государства. Авторы приходят к выводу, что советская исправительно-трудовая система не возникла революционно сама по себе, а она выросла из тюремной системы царской России, когда уже были сформированы промышленно-тюремные кусты будущего экономического освоения Урала.
КАК ИЗМЕНИТСЯ КАДРОВЫЙ УЧЕТ В ОРГАНИЗАЦИИ, В СВЯЗИ С ПЕРЕХОДОМ В ЦИФРОВУЮ СРЕДУ
Creators: name: Фатеева Н.Б.
name: Петрякова С.В.
name: Петрова Л.Н.
name: Алимарданова Н.А.
name: Симачкова Н.Н.
Publisher: name: Образование и право
Year: 2022
Subjects: электронный кадровый документооборот
работники и работодатели
локальные нормативные акты
трудовые отношения
электронные цифровые подписи.

description: Переход на электронный документооборот в организациях стоит остро сейчас на повестке дня у работодателей. Чтобы перейти на электронный документооборот, необходимо выбрать информационную систему, через которую будем обмениваться документами, программное обеспечение, разработать локальные нормативные акты. Далее надо уведомить сотрудников о переходе на электронный формат и получить от них заявление о согласии или отказе. Оформить электронные подписи и обмениваться документами в электронном виде.
Self-Fourier transform and self-Fourier beams due to parabolic potential
Creators: name: Zhang, Yiqi
name: Liu, Xing
name: Belić, Milivoj R.
name: Zhong, Weiping
name: Petrović, Milan S.
name: Zhang, Yanpeng
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We investigate the propagation of light beams including Hermite-Gauss, Bessel-Gauss and finite energy Airy beams in a linear medium with parabolic potential. Expectedly, the beams undergo oscillation during propagation, but quite unexpectedly they also perform automatic Fourier transform, that is, periodic change from the beam to its Fourier transform and back. The oscillating period of parity-asymmetric beams is twice that of the parity-symmetric beams. In addition to oscillation, the finite-energy Airy beams exhibit periodic inversion during propagation. Based on the propagation in parabolic potential, we introduce a class of optically-interesting beams that are self-Fourier beams -- that is, the beams whose Fourier transforms are the beams themselves.
description: 11 pages, 5 figures, Ann. Phys., in press
ИСЛОҲОТЛАР ЖАРАЁНИДА ОММАВИЙ АХБОРОТ ВОСИТАЛАРИНИНГ РОЛИ ВА РИВОЖЛАНИШ ТЕНДЕНЦИЯЛАРИ
Creators: name: Сеитназарова, Гулжаҳан
name: Бахитова, Жасмина
Publisher: name: Zenodo
Year: 2024

description: Мазкур мақолада Ўзбекистон янгиланишида ОАВ олдида турган асосий вазифалар, журналистларнинг ислоҳотлар жараёнидаги ўрни, ижтимоий мавқеи ҳамда матбуонинг ислоҳотлар ва унинг аҳамиятини аҳолининг кенг қатламига етказишдаги ўрни хусусида сўз боради.
Compartmentalization, Viral Evolution, and Viral Latency of HIV in the CNS
Creators: name: Sturdevant, Christa Buckheit
name: Arrildt, Kathryn Twigg
name: Tompkins, Lauren A.
name: Kincer, Laura P.
name: Bednar, Maria M.
name: Dukhovlinova, Elena
name: Swanstrom, Ronald
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Human immunodeficiency virus type 1 (HIV-1) infection occurs throughout the body, and can have dramatic physical effects, such as neurocognitive impairment in the central nervous system (CNS). Furthermore, examining the virus that resides in the CNS is challenging due to its location and can only be done using samples collected either at autopsy, indirectly form the cerebral spinal fluid (CSF), or through the use of animal models. The unique milieu of the CNS fosters viral compartmentalization as well as evolution of viral sequences, allowing for new cell types, such as macrophages and microglia, to be infected. Treatment must also cross the blood brain barrier adding additional obstacles in eliminating viral populations in the CNS. These long-lived infected cell types and treatment barriers may affect functional cure strategies in people on highly active antiretroviral therapy (HAART).
К ВОПРОСУ КВАЛИФИКАЦИИ И НАЗНАЧЕНИЯ НАКАЗАНИЯ ЗА ПРЕСТУПЛЕНИЯ, ПОСЯГАЮЩИЕ НА ПРАВА И СВОБОДЫ БЕСПОМОЩНОГО ПОТЕРПЕВШЕГО
Creators: name: Шикула И.Р.
name: Каменева З.В.
Publisher: name: Образование и право
Year: 2022
Subjects: уголовно-правовая охрана
защита потерпевшего в беспомощном состоянии
насильственные преступления
квалификация
назначение наказания
судебная практика.

description: В статье авторами рассматриваются актуальные проблемы квалификации преступлений в отношении потерпевших, находящихся в беспомощном состоянии, разработаны предложения по оптимизации уголовного законодательства в части квалификации и назначения наказания за преступления, посягающие на права и свободы потерпевшего, находящегося в беспомощном состоянии. Юридическая наука не содержит четкого и однозначного понятия «беспомощное состояние», которое имеет уголовно-правовую значимость, не содержит критерии оценивания состояния беспомощности, не в полной мере разработанные конкретные рекомендации по вопросам квалификации преступлений, совершаемых в отношении лиц, находящихся в беспомощном состоянии, создают определенные препятствия в уголовно-правовой охране их прав и свобод.
Implementation Research for the Prevention of Mother-to-Child HIV Transmission in Sub-Saharan Africa: Existing Evidence, Current Gaps, and New Opportunities
Creators: name: Chi, Benjamin H.
name: Aarons, Gregory A.
name: Bhardwaj, Sanjana
name: Carter, Bryan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Tremendous gains have been made in the prevention of mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. Ambitious goals for the “virtual elimination” of pediatric HIV appear increasingly feasible, driven by new scientific advances, forward-thinking health policy, and substantial donor investment. To fulfill this promise, however, rapid and effective implementation of evidence-based practices must be brought to scale across a diversity of settings. The discipline of implementation research can facilitate this translation from policy into practice; however, to date, its core principles and frameworks have been inconsistently applied in the field. We reviewed the recent developments in implementation research across each of the four “prongs” of a comprehensive PMTCT approach. While significant progress continues to be made, a greater emphasis on context, fidelity, and scalability – in the design and dissemination of study results – would greatly enhance current efforts and provide the necessary foundation for future evidence-based programs.
Gaussian kernel GARCH models
Creators: name: Zhang, Xibin
name: King, Maxwell L.
Publisher: name: Monash University
Year: 2022
Subjects: Econometric and statistical methods
Econometrics not elsewhere classified

description: This paper aims to investigate a Bayesian sampling approach to parameter estimation in the GARCH model with an unknown conditional error density, which we approximate by a mixture of Gaussian densities centered at individual errors and scaled by a common standard deviation. This mixture density has the form of a kernel density estimator of the errors with its bandwidth being the standard deviation. This study is motivated by the lack of robustness in GARCH models with a parametric assumption for the error density when used for error-density based inference such as value-at-risk (VaR) estimation. A contribution of the paper is to construct the likelihood and posterior of the model and bandwidth parameters under the kernel-form error density, and to derive the one-step-ahead posterior predictive density of asset returns. We also investigate the use and benefit of localized bandwidths in the kernel-form error density. A Monte Carlo simulation study reveals that the robustness of the kernel-form error density compensates for the loss of accuracy when using this density. Applying this GARCH model to daily return series of 42 assets in stock, commodity and currency markets, we find that this GARCH model is favored against the GARCH model with a skewed Student t error density for all stock indices, two out of 11 currencies and nearly half of the commodities. This provides an empirical justification for the value of the proposed GARCH model.
Youth, Technology, and HIV: Recent Advances and Future Directions
Creators: name: LeGrand, Sara
name: Muessig, Kathryn E.
name: Hightow-Weidman, Lisa B.
name: Bauermeister, Jose
name: Zhang, Chen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Technology, including mobile technologies and social media, offers powerful tools to reach, engage, and retain youth and young adults in HIV prevention and care interventions both in the United States and globally. In this report we focus on HIV, technology, and youth, presenting a synthesis of recently published (Jan 2014-May 2015) observational and experimental studies relevant for understanding and intervening on HIV risk, prevention and care. We present findings from a selection of the 66 relevant citations identified, highlighting studies that demonstrate a novel approach to technology interventions among youth in regard to content, delivery, target population or public health impact. We discuss current trends globally and in the US in how youth are using technology, as well as emergent research issues in this field – including the need for new theories for developing technology-based HIV interventions and new metrics of engagement, exposure, and evaluation.