cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Computerized Decision Making Applied to the Diagnosis of Lactic Acidosis
Creators: name: Yeh, Minken
Publisher: name: University of Utah
Year: 2012

description: Patients with elevated lactic acid have a high mortality rate. In a retrospective search of the computerized LDS Hospital patient file, from February 1976 through August 1978, it was found that 198 patients had lactic acidosis and of those 118 died. The mortality rate was about 60%, However, only 2% of the patients admitted ever had the lactic acid test. Means of predicting and diagnosing lactic acidosis from other more common tests would therefore be helpful. Studies were undertaken to predict lactic acidosis from other more common laboratory tests (the SMA-6, SMA-12, C3C, and the blood gas test).  STUDY I used the first set of data after patient's admission. Three multivariate statistical methods were used* linear discriminant analysis, Bayes method with equal bin widths, and Bayes method with equal bin counts. Linear discriminant analysis was the best method if the blood gas variables were included. True postive rate was 54,2% and true negative rate was 97.5% when the predictive value (true positives divided by the sum of true positives and false  positives)  was 23.3%.   Bayes method with equal bin widths yielded the best results when only the SMA-6, SMA-12, and G3C tests variables were used. True positive rate was 40.0% and true negative rate was 98.7% when the predictive value was 23.5%.  In STUDY II, only patients who had the first high lactic acid within 24 hours of admission were included. Again the three multivariate methods were utilized. Linear discriminant analysis always yielded the best results. ''When using only variables from SfMA-6, SMA-12, and C3C tests, the result was better than in STUDY I.  However, if the blood gas variables were included, the results were not as good as in STUDY I.  In STUDY III, we evaluated patient information for three different time periods* from 0 to 6 hours, 6 to 12 hours, and) 2 to 24 hours before the first high lactic acid result. Linear discriminant functions obtained from the closest set of data before lactic acidosis and from STUDY II were tested and compared. In the period from 0 to 6 hours before the first high lactic acid, discriminant functions from the closest data and the STUDY II data performed about the same if the blood gas variables were included. . True positive rate was 60.0% while true negative rate was 97.6%. When only variables from the SA^-6, SMA-12, and  CBC  were   used,   the  discriminant  functions   from   STUDY   II  gave the better results. True positive rate was 50.8% while true negative rate was 98.7%. For the periods from 6 to 12 hours and 12 to 24 hours before the first high lactic acid, none of  the  discriminant   functions  worked  well.  The results of the above studies warrant a clinical trial.
Additional file 5 of Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
Creators: name: Abong, Raphael Awah
name: Glory N. Amambo
name: Ndongmo, Patrick W. Chounna
name: Njouendou, Abdel Jelil
name: Ritter Manuel
name: Amuam Andrew Beng
name: Esum, Mathias Eyong
name: Kebede Deribe
name: Fru-Cho, Jerome
name: Fombad, Fanny F.
name: Nji, Theobald Mue
name: Enyong, Peter Ivo
name: Poole, Catherine B.
name: Pfarr, Kenneth
name: Hoerauf, Achim
name: Carlow, Clotilde K. S.
name: Wanji, Samuel
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 5 S1 Table. Data input for the simplified interface of three-tests in one-population model (Walter and Irwig model) in Bafia and Melong Health Districts.
Single-leg cycling, an evaluation of pedal powers
Creators: name: Thomas, Larry Nathan
Publisher: name: University of Utah
Year: 2012
Subjects: Biomechanics
Cycling
Single-leg

description: Benefits of single-leg cycling may be compromised because single- and double-leg cycling are biomechanically different. Specifically, during normal double-leg (2L) cycling the gravitational forces acting on each leg are essentially balanced by the contralateral limb and thus do not require active leg flexion. Conversely, single-leg (SL) cycling requires active leg flexion. Recently, The Neuromuscular Function Laboratory at the University of Utah devised a counterweighted cycling crank that facilitates SL cycling with similar biomechanics to normal 2L cycling. The purpose of this study was to evaluate SL noncounterweighted pedal powers (SL-0), SL counterweighted pedal powers at 20 and 30 pounds (SL-20 & SL-30), and compare to normal 2L cycling. Eleven trained cyclists (age: 39 ± 7 years, mass: 172 ± 42 pounds, height: 68 ± 3.5 inches) performed SL cycling with their right leg and 2L cycling with both legs. Pedal powers were calculated during each trial using a force measuring pedal and instrumental spatial linkage system. Participants warmed up for 5 minutes and then performed 6 randomized cycling trials while maintaining 90 rpm at 200 watts 2L, and 100 watts SL-0, SL-20, and SL-30. One-way within-subjects ANOVAs indicated significant effects for cycling condition for both extension [F(1,62) = 26.17, p < .01., partial ?2 = .72] and flexion [F(1,73) = 50.68, p < .01., partial ?2 = .835]. Follow-up pairwise comparisons indicated that 2L cycling generated the most power, 2L-0 the least, with SL-20 & SL-30 falling in between the two extremes, but still significantly different from the low and the high. Within-subjects ANOVAs were conducted using mean-adjusted body weight as a covariate still showed significant differences for power generated under different cycling conditions; also a significant interaction between cycling condition and body weight was observed. The magnitude of power decreased significantly when comparing SL-0 to 2L. However, adding counterweight (SL-20, SL-30) demonstrates evidence that counterweighted cycling brings pedal powers closer to 2L cycling in a SL cycling model. In conclusion, 2L cycling is not the same biomechanical task as SL-0 cycling. Counterweighted single-leg cycling produces similar pedal power to 2L cycling, but the exact application of the counterweight needs further investigation. Properly counterweighted SL cycling may be a beneficial training and rehabilitation modality.
Additional file 6 of Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
Creators: name: Abong, Raphael Awah
name: Glory N. Amambo
name: Ndongmo, Patrick W. Chounna
name: Njouendou, Abdel Jelil
name: Ritter Manuel
name: Amuam Andrew Beng
name: Esum, Mathias Eyong
name: Kebede Deribe
name: Fru-Cho, Jerome
name: Fombad, Fanny F.
name: Nji, Theobald Mue
name: Enyong, Peter Ivo
name: Poole, Catherine B.
name: Pfarr, Kenneth
name: Hoerauf, Achim
name: Carlow, Clotilde K. S.
name: Wanji, Samuel
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 6 S2 Table. Socio-demographic characteristics and distribution of participants screened by microscopy in the Bafia Health District.
Im hinteren Theil des Nanzathals
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860
Subjects: Gletscher

description: Blick ins Nanztal mit dem Fletschhorn und Mattwaldhorn im Hintergrund. Das Mattwaldhorn wurde früher, so auch auf der Dufourkarte von 1862, als Simmelihorn bezeichnet
description: nach Bühlmann ; IM
description: Initialen "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Dyscinetus dubius
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dynastidae
Dyscinetus
Dyscinetus dubius

description: Dyscinetus dubius (Olivier, 1789)
Melolontha dubia Olivier 1789: 32 (French Guiana)
= Melolontha geminata Fabricius 1801b: 166 (South America)
Distribution. Guyana: Erichson 1848: 561 (as Chalepus geminatus); Bodkin 1919: 216 (as D. geminatus); Endrödi 1966a: 387; Dechambre 1979c: 167; Joly and Escalona 2010: 218; Moore et al. 2018b: 265. Suriname: Uyttenboogaart 1902: 116; Endrödi 1966a: 387; Dechambre 1979c: 167; Joly and Escalona 2010: 218; Moore et al. 2018b: 265; MHCN; NZCS; RMNH. French Guiana: Olivier 1789: 32 (as Melolontha dubia); Endrödi 1966a: 387; Dechambre 1979c: 167; Joly and Escalona 2010: 218; Duranton 2011: 18; Ponchel 2011: 60; Dupuis 2016b: 109; Moore et al. 2018b: 265; MHCN. Brazil (NA): Arrow 1937b: 17; Blackwelder 1944: 253; Endrödi 1966a: 387 (NA); Dechambre 1979c: 167; Andreazze and Fonseca 1998: 62 (NA); Joly and Escalona 2010: 218 (NA); Moore et al. 2018b: 265. Venezuela (EO): Arrow 1937b: 17; Blackwelder 1944: 253; Endrödi 1966a: 387 (EO); Dechambre 1979c: 167; Joly and Escalona 2010: 218 (EO); Moore et al. 2018b: 265 (EO). Other: Fabricius 1801b: 166 (South America - as Melolontha geminata); Arrow 1937b: 17 (Ecuador, Trinidad and Tobago); Blackwelder 1944: 253 (Ecuador, Trinidad and Tobago); Endrödi 1966a: 387 (Argentina, Bolivia, Chile, Colombia, Costa Rica, Cuba, Ecuador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Trinidad and Tobago), 1985a: 169 (Argentina–Mexico); Dechambre 1979c: 167 (Bolivia, Central America, Colombia, Cuba, Ecuador, Mexico, Trinidad and Tobago); Joly and Escalona 2010: 218 (Argentina, Bolivia, Chile, Colombia, Costa Rica, Cuba, Ecuador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Trinidad and Tobago); Ratcliffe et al. 2013: 239 (Argentina–Mexico); Moore et al. 2018b: 265 (Argentina, Belize, Bolivia, Chile, Colombia, Costa Rica, Cuba, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Trinidad and Tobago).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 187, DOI: 10.5281/zenodo.3678492
Synthesis and evaluation of anticancer activities of 2- or 4-substituted 3-(N-benzyltriazolylmethyl)-13α-oestrone derivatives
Creators: name: Jójárt, Rebeka
name: Tahaei, Seyyed Ashkan Senobar
name: Trungel-Nagy, Péter
name: Kele, Zoltán
name: Minorics, Renáta
name: Paragi, Gábor
name: Zupkó, István
name: Mernyák, Erzsébet
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Hematology

description: 2- or 4-Substituted 3-N-benzyltriazolylmethyl-13α-oestrone derivatives were synthesised via bromination of ring A and subsequent microwave-assisted, Pd-catalysed C(sp2)–P couplings. The antiproliferative activities of the newly synthesised brominated and phosphonated compounds against a panel of human cancer cell lines (A2780, MCF-7, MDA-MB 231) were investigated by means of MTT assays. The most potent compound, the 3-N-benzyltriazolylmethyl-4-bromo-13α-oestrone derivative exerted substantial selective cell growth-inhibitory activity against A2780 cell line with a submicromolar IC50 value. Computational calculations reveal strong interactions of the 4-bromo derivative with both colchicine and taxoid binding sites of tubulin. Disturbance of tubulin function has been confirmed by photometric polymerisation assay.
Additional file 2 of Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
Creators: name: Abong, Raphael Awah
name: Glory N. Amambo
name: Ndongmo, Patrick W. Chounna
name: Njouendou, Abdel Jelil
name: Ritter Manuel
name: Amuam Andrew Beng
name: Esum, Mathias Eyong
name: Kebede Deribe
name: Fru-Cho, Jerome
name: Fombad, Fanny F.
name: Nji, Theobald Mue
name: Enyong, Peter Ivo
name: Poole, Catherine B.
name: Pfarr, Kenneth
name: Hoerauf, Achim
name: Carlow, Clotilde K. S.
name: Wanji, Samuel
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2 S2 Fig Detection limits of OvActin real-time PCR.
Lago de Zozanne 2704 mt unter dem Col de Torrent im Einfischthal
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860
Subjects: Gletscher

description: Blick auf einen Bergsee, gemäss Titel der Lago Zozanne, mit Bergen und Gletscher im Hintergrund. Der Bergsee Lac de Autannes, auf der Dufourkarte als L. Zozanne bezeichnet, liegt unterhalb des Col de Torrent, auf der Südseite des Sasseneire. Gemäss Dufourkarte von 1863 liegen jedoch die Gletscher und Eisfelder auf der Nordseite mit dem davor liegenden Lac de Lona
description: nach Bühlmann ; IM
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Computerized weaning of childhood respiratory failure
Creators: name: Maloney, Christopher Gerard
Publisher: name: University of Utah
Year: 2012
Subjects: Respirators
Medical Equipment
Children

description: Acute respiratory failure (ARF) is a major reason for admission to a pediatric intensive care unit. Endotracheal intubation and mechanical ventilation is a method of life support for ARF. Mechanical ventilation is intended to be a temporary measure with an ultimate goal of extubation and a return by the patient to natural breathing. Weaning is the process of slowly removing ventilator support in order to achieve this goal. A standardized process for weaning children from mechanical ventilation does not exist. This dissertation describes how use of a computerized pediatric ventilator weaning protocol is safe and efficient.  Standardization of process reduces variation in clinical practice and results in improved outcomes. Protocols provide standardized medical decision making. Computerized protocols are the most robust form of protocols and can assist clinicians at the point of care by providing patient-specific instructions.  A paper-based protocol to wean children with ARF was developed by a group of pediatric critical care clinicians.   Protocol knowledge content was derived from outcomes in the medical literature and local practice. The protocol consisted of eight flow charts executed in series. Sixteen data elements were required to execute the entire protocol. Within a flow chart, time-sensitive, patient-specific instructions were provided.  Following development and validation, the paper-based pediatric ventilator weaning protocol was computerized. Each flow chart was broken down into specific states corresponding to computerized if-then-else" logic statements. A commercially available rules engine was integrated with a web-browser based decision-support infrastructure to continually monitor patient specific data elements and deliver explicit instructions to clinicians.  Upon completion of the computerized pediatric ventilator weaning protocol a prospective randomized controlled trial was conducted to compare the protocol to a typical-physician approach to weaning children from mechanical ventilation. Children in the protocol group were weaned significantly faster than children in the control group (8 hours vs. 28.5 hours p < 0.002). No complications of mechanical ventilation occurred in either group.  These studies demonstrate that a pediatric ventilator weaning protocol can be developed, computerized and implemented to safely and efficiently assist clinicians in weaning children from mechanical ventilation. Standardizing processes for the delivery of healthcare can improve outcomes.
Von Tufleren ob Zermatt
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: nach Bühlmann ; IM
description: Initialen "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Von Jezzinen ob Nieder Gampeln : gegen Turtman Ems und Turtmanthal und Weisshorn
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860
Subjects: Wallis

description: nach Bühlmann ; IM
description: Initialen "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
In the Loop: The Application of System Dynamics in Transport
Creators: name: Harrison, Gillian
name: Gühnemann, Astrid
name: Shepherd, Simon
name: Jittrapirom, Peraphan
name: Gómez Vilchez, Jonatan J.
name: Pfaffenbichler, Paul
Publisher: name: Zenodo
Year: 2024
Subjects: subject: System Dynamics
subject: Transport
subject: Systematic Review
subject: Insights

description: This poster is designed to present to the transport research community the wide existing body of work and potential future applications of the method of System Dynamics (SD) within transport research. We introduce the reader to the basic concepts of the SD method, and discuss previous reviews of academic SD papers, before setting out a systematic review on SD in transport. We find that over 400 papers have been published over the past 40 years, with over 80% in the past decade. The most popular topic is strategic and sustainable policy, but alternative fuel vehicle uptake and maritime applications have been increasingly popular over recent years. SD is also being adopted outside academia in both consultancy and governmental organisations, so we believe that this paper is a timely contribution to embedding SD as a leading emerging method within transport research, which will encourage all members of the community to consider adopting it within their toolkit.
Dyscinetus dytiscoides Arrow 1911
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dynastidae
Dyscinetus
Dyscinetus dytiscoides

description: § Dyscinetus dytiscoides Arrow, 1911
Dyscinetus dytiscoides Arrow 1911b: 168 (Venezuela, Colombia)
Distribution. Venezuela (EO): Arrow 1911b: 168, 1937b: 17; Blackwelder 1944: 253; Endrödi 1966a: 388, 1985a: 170 (as Chalepides dytiscoides); Joly and Escalona 2010: 207 (EO); Moore et al. 2018b: 266 (EO). Other: Arrow 1911b: 168 (Colombia), 1937b: 17 (Colombia); Blackwelder 1944: 253 (Colombia); Endrödi 1966a: 388 (Bolivia, Colombia, Peru), 1985a: 170 (Bolivia, Colombia, Peru - as Chalepides dytiscoides); Joly and Escalona 2010: 207 (Bolivia, Colombia, Peru); Moore et al. 2018b: 266 (Bolivia, Colombia, Peru).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 187, DOI: 10.5281/zenodo.3678492
Vispachbrücke bey Stalden
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860
Subjects: Brücke
Wallis

description: Die Chibrücke oder Chibrigga, die älteste heute noch erhaltenen Staldner Brücke, ab 1544 von Ulrich Ruffiner erbaut
description: nach Bühlmann ; IM
description: Initialen "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Evaluation of a prescription medication voucher system for a homeless population
Creators: name: Sayeed, Azra Talat
Publisher: name: University of Utah
Year: 2012
Subjects: Health Services
Pharmacy

description: The last decade saw a resurgence of the homeless population in the United States. In order to rectify the phenomenon of homelessness, the Stewart B. McKinney Homeless Assistance Act was created in 1987. Under this Act, Congress made emergency funds available for homeless programs in 109 communities, including Salt Lake City, Utah. In January 1988, Salt Lake City obtained McKinney Act funding and created the Wasatch Health Care Program of medical services and substance abuse. Part of the medical services extended through the Act includes provision of prescription medication via a prescription voucher, after the homeless person has been seen by a medical practitioner.  This thesis has traced the phenomenon of homelessness in the United States from the earlier part of the 20th century to the 1980s. Demographics of the homeless population in the United States have been studied and the reasons behind homelessness have been discussed. The study has evaluated the use of the prescription voucher for the homeless person. The analysis has been used to describe and quantify the homeless population who have had their prescriptions filled at local pharmacies in Salt Lake City, Utah.
Capelle zur Hochstegen im Feethal gegen das Almagellhorn
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: Die Wallfahrtskapelle Maria zur Hohen Stiege in Saas Fee
description: nach Bühlmann ; v J Müller
description: "v J Müller" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Zwischen Satarma und Barthelemi im Val de Arolla gegen Piz d' Arolla
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: Copie nach Bühlmann ; IM
description: Initialen "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Bey der Distelalp im Saasthal gegen Monte Moropass
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: nach Bühlmann ; [Johann Müller-Wegmann]
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Dyscinetus fimosus
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dynastidae
Dyscinetus
Dyscinetus fimosus

description: Dyscinetus fimosus (Herbst, 1789)
Scarabaeus fimosus Herbst 1789: 248 (Suriname)
Distribution. Suriname: Herbst 1789: 248 (as Scarabaeus fimosus); Moore et al. 2018b: 267. “Guianas”: Arrow 1937b: 17; Blackwelder 1944: 253. Venezuela: Roze 1955: 58; Moore et al. 2018b: 267. Other: Endrödi 1966a: 389 (none); Endrödi 1985a (not mentioned).
Note. Herbst (1789: 248) mentions in the description of his Scarabaeus fimosus that the species is said to be common in Suriname, which he considers curious as he has not seen it before, even though he has seen many insects from Suriname. Endrödi (1966a: 389) mentions that the species is unknown to him and that the type could not be found. Moore et al. (2018b: 267) mention the species for Venezuela, based on records in Roze (1955: 58), but the species is not mentioned in the synopsis of the genus in Venezuela by Joly and Escalona (2010). The two specimens recorded by Roze are supposed to be in two different museums in Caracas, Venezuela. Without types and without being able to confirm the identification of Roze’s specimens, this species remains a species inquirendum.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on pages 187-188, DOI: 10.5281/zenodo.3678492
Kapelle zur Hochstegen im Feethal
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: Die Wallfahrtskapelle Maria zur Hohen Stiege in Saas Fee
description: nach Bühlmann ; IM
description: "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Attitude of Nursing Personnel Toward Disabled Persons and Performance of Rehabilitative Aspects of Nursing Care
Creators: name: Gilliland, Alice Kelso
Publisher: name: University of Utah
Year: 2012

description: Questionnaires were distributed to 198 registered nurses and 1979 licensed practical nurses in five hospitals to determine:  1) their attitude toward disabled persons through response to the Attitude Toward Disabled Persons Scale, developed by the Human Resources Foundation; 2) their performance level of the rehabilitative aspects of nursing care through response to the Performance of Rehabilitative Aspects of Nursing Care Scale, developed by the author; and 3) the correlation of attitude with performance.  It was expected that attitude and performance would be correlated; a low, but significant correlation of .19 (p = .01) was found.  It was also expected that registered nurses, by virtue of their higher level of educational preparation, would score higher on both instruments, but the results did not show this to be so.  There was no significant difference in either attitude or performance between the two levels of nursing personnel.  Mean score of the two scales revealed that nursing personnel exhibited somewhat lower levels of attitude and performance scores than would be considered, in the opinion of the author, to be indicative of an accepting attitude toward the disabled person and the performance of a high quality of nursing care in relation to the rehabilitative needs of patients.  Although generalizations made from the results of this study should be drawn with caution, some inferences can be derived which have implications for the future provision of a high quality of nursing care.
Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones
Creators: name: Elzahhar, Perihan A.
name: Alaaeddine, Rana A.
name: Nassra, Rasha
name: Ismail, Azza
name: Labib, Hala F.
name: Temraz, Mohamed G.
name: Belal, Ahmed S. F.
name: El-Yazbi, Ahmed F.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: The work reported herein describes the synthesis of a new series of anti-inflammatory pyrazolyl thiazolones. In addition to COX-2/15-LOX inhibition, these hybrids exerted their anti-inflammatory actions through novel mechanisms. The most active compounds possessed COX-2 inhibitory activities comparable to celecoxib (IC50 values of 0.09–0.14 µM) with significant 15-LOX inhibitory activities (IC50s 1.96 to 3.52 µM). Upon investigation of their in vivo anti-inflammatory activities and ulcerogenic profiles, these compounds showed activity patterns equivalent or more superior to diclofenac and/or celecoxib. Intriguingly, the most active compounds were more effective than diclofenac in suppressing monocyte-to-macrophage differentiation and inflammatory cytokine production by activated macrophages, as well as their ability to induce macrophage apoptosis. The latter finding potentially adds a new dimension to the previously reported anti-inflammatory mechanisms of similar compounds. These compounds were effectively docked into COX-2 and 15-LOX active sites. Also, in silico predictions confirmed the appropriateness of these compounds as drug-like candidates.
Zmutt gegen Findelngletscher
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: nach Bühlmann ; [Johann Müller-Wegmann]
description: "IM" in Bleistift unterhalb Titel
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Recent advance in the discovery of tyrosinase inhibitors from natural sources via separation methods
Creators: name: Zhang, Xiao-wei
name: Bian, Guang-li
name: Kang, Pei-ying
name: Cheng, Xin-jie
name: Yan, Kai
name: Liu, Yong-li
name: Gao, Yan-xia
name: Li, De-qiang
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Tyrosinase (TYR) inhibitors are in great demand in the food, cosmetic and medical industrials due to their important roles. Therefore, the discovery of high-quality TYR inhibitors is always pursued. Natural products as one of the most important sources of bioactive compounds discovery have been increasingly used for TYR inhibitors screening. However, due to their complex compositions, it is still a great challenge to rapid screening and identification of biologically active components from them. In recent years, with the help of separation technologies and the affinity and intrinsic activity of target enzymes, two advanced approaches including affinity screening and inhibition profiling showed great promises for a successful screening of bioactive compounds from natural sources. This review summarises the recent progress of separation-based methods for TYR inhibitors screening, with an emphasis on the principle, application, advantage, and drawback of each method along with perspectives in the future development of these screening techniques and screened hit compounds.
Der  Ladstäg 1932 oder Brücke bey Altenstaffeln im Eginen Thal
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: Der Griesgletscher zwischen dem Fülhorn und dem Nufenenstock mit der Brücke in Ladstafel im Vorder- und Altstafel im Mittelgrund
description: [nach Bühlmann] ; [Johann Müller-Wegmann]
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Additional file 9 of Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
Creators: name: Abong, Raphael Awah
name: Glory N. Amambo
name: Ndongmo, Patrick W. Chounna
name: Njouendou, Abdel Jelil
name: Ritter Manuel
name: Amuam Andrew Beng
name: Esum, Mathias Eyong
name: Kebede Deribe
name: Fru-Cho, Jerome
name: Fombad, Fanny F.
name: Nji, Theobald Mue
name: Enyong, Peter Ivo
name: Poole, Catherine B.
name: Pfarr, Kenneth
name: Hoerauf, Achim
name: Carlow, Clotilde K. S.
name: Wanji, Samuel
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 9 S5 Table. Socio-demographic characteristics and distribution of participants that volunteered for the follow up study in the Melong health district.
Dyscinetus mendax Joly and Escalona 2010
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Dynastidae
Dyscinetus
Dyscinetus mendax

description: Dyscinetus mendax Joly and Escalona, 2010
Dyscinetus mendax Joly and Escalona 2010: 227 (Venezuela)
Distribution. Suriname: Joly and Escalona 2010: 227; Moore et al. 2018b: 269; MHCN; NZCS; RMNH. French Guiana: Joly and Escalona 2010: 227; Dupuis 2016b: 102, 109; Moore et al. 2018b: 269; MHCN; NZCS. Brazil (NA): Joly and Escalona 2010: 227 (NA); Moore et al. 2018b: 269. Venezuela (EO): Joly and Escalona 2010: 227 (EO); Moore et al. 2018b: 269 (EO). Other: Joly and Escalona 2010: 227 (Bolivia, Colombia, Ecuador, Peru, Trinidad and Tobago); Moore et al. 2018b: 269 (Bolivia, Colombia, Ecuador, Martinique, Peru, Trinidad and Tobago).
Note. For additional records of Dyscinetus mendax, see D. olivaceus. Explanations are given in the notes at D. olivaceus.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 188, DOI: 10.5281/zenodo.3678492
Time studies in underground coal mining
Creators: name: Koch, Ludwig W.
Publisher: name: University of Utah
Year: 2012
Subjects: Coal mines and mining, Utah

description: Machine performance is the key to higher production and bigger profits in present day coal mining. By far the most important machine in a mechanized coal mining operation is the mobile loader. It must load the coal that pays for the entire operation, and its performance, therefore, is the deciding factor controlling success or failure of the mine.  This paper attemps to analyze the loading and hauling cycle of a producing section, including the actions of the mobile loader and one or more shuttle cars. A simple and effective method of conducting time studies is outlined in the first chapter by which not only the loading operation but also other operations, necessary to keep the mobile loader in coal, can be analyzed and studied.  In the second chapter an attempt is made to evaluate time studies conducted according to the outlined method. The studies had been made in Kenilworth Mine and Castle Gate Mine. Both mines are located near Helper in Carbon County, Utah. They are properties of the Independent Coal and Coke Company. Their productions are 3, 000 and 2, 000 tons per day, respectively. The room and pillar method is used exclusively in both mines. All openings are driven eighteen to twenty two feet wide and ten to twelve feet high. Pillars are recovered on the retreat* The loading is done with Joy 11 BU loaders in all sections. The loaders discharge into Joy 10 SC shuttle cars that empty directly into mine cars.  Recommendations are made in the third chapter which could improve the performance of mobile loaders in general and the operations of Kenilworth mine and Castle Gate mine in particular.  The theoretical considerations in the last chapter deal with requirements that must be met by a high producing section. They also show some limitations of the use of mobile loader units in conventional room and pillar mining - at least with the present day equipment.
Colonial language and postcolonial linguistic hybridity
Creators: name: Watts, Jarica Linn
Publisher: name: University of Utah
Year: 2012
Subjects: Hybridity
Language change
Language crossing
Linguabridity, Linguistics
Postcolonial literature

description: This dissertation project applies community-specific linguistic studies to various postcolonial text;s, thereby offering readers an alternative way of analyzing the patterns of language usage in postcolonial literature. I use linguistic studies to help treat these communities not as they were-long-time colonies of the British Empire-but rather as they are now: multilingual societies that serve as gateways into complex webs of identity construction and language usage. In this vein, I approach postcolonial literature in relation to: (1) how the text;s use language to either include or exclude others; (2) how the characters interpret and respond to the mix of original and new languages; (3) how  language usage either deters from or solidifies the sense of belonging together on the part of colonial natives; and (4) how language functions as a force in each text; considered.   The particular linguistic studies I use have not generally been applied to literature, but I show that these theories can be mapped onto literary text;s in very compelling ways. Because language is constructed differently in different regions, it only makes sense that linguistic identity has to be studied within specific societies; Africa's multilingualism, for example, has often been described as on par with European multilingualism, yet this is theoretically misleading because whereas European multilingualism involves several written languages, the African context; involves only a few written languages (such as Yoruba and Gikuyu) existing alongside oral languages founded on oral cultures and transmitted orally. Given, then, that this dissertation examines literary text;s through the lens of local language, its findings are useful in that they reveal widely disparate modes of colonial resistance that tend to challenge more traditional postcolonial readings and  interpretations.
Vieschergletscher : Anno 1836
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1836
Subjects: Gletscher
Gletschertor

description: nach Bühlmann
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Bey Eisten gegen Platten & Ried und gegen die Faldunfurca
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1860

description: nach Bühlmann
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Transfected mesenchymal stem cells in a thermoreversible hydrogel matrix for the treatment of myocardial infarction
Creators: name: Borden, Bradley Alan
Publisher: name: University of Utah
Year: 2012
Subjects: Hydrogel
Stem cells
Transfected mesenchymal stem cells
Thermoreversible

description: This research presented here was conducted for the purpose of finding an effective method of treating myocardial infarction utilizing genetically modified mesenchymal stem cells delivered in a thermoresponsive hydrogel. Heart disease is the most common cause of death in the industrialized world and treatment still has much room for improvement. Growth factor treatments have shown promise in revascularizing the infarcted tissue, provided either as a recombinant protein or by means of gene therapy. Stem cells are also a means of treating disease that is growing in effectiveness, although cells injected to the heart are often plagued by poor engraftment at the injection site. This research is divided into three main sections. The first deals with the selection of an appropriate growth factor to be used in the study. Testing included quantifying the pro-angiogenic effect of the multiple growth factors on human endothelial cells as well as the growth factors' effects on the proliferation of the cells. Plasmid DNA constructs for the growth factors of interest were created for use in these studies. Growth factors were also tested for their influence on the mesenchymal stem cells. It was found that none of the growth factors or polymers used for DNA complexation and transfection resulted in differentiation of the stem cells. After completing this phase of the research, platelet-derived growth factor "C" was chosen for use in the following phases of the work. The second phase dealt with the characterization of a scaffold to be used with the transfected stem cells. After injection of cells in saline to the myocardium, 90% of the cells can be lost from the injection site. The hydrogel PoligoGel© from Samyang Corp. was found to be compatible with the stem cells, being both nontoxic, as well as not affecting differentiation of the cells. The final portion of the research was the application of the growth factor, stem cells, and scaffold in vivo in a rat model to observe the effects of the treatment in the infarcted heart. Lewis rats underwent a coronary artery ligation to create an infarcted region of the heart. Stem cells transfected to express platelet-derived growth factor ‘C' were then injected into the heart in a thermoreversible scaffold. The effectiveness of the treatment was quantified by analyzing MRI scans of the heart, as well as the biodistribution of the injected cells. The biodistribution was performed by RT-PCR and showed a 15-fold increase in cells retained at the heart for groups injected with cells in a thermoreversible scaffold versus those injected in saline. The MRI data did not show any statistical significance between groups.
Bey Zinal im Einfischthal
Creators: name: Steiger, Johann Martin
Publisher: name: [s.n.]
Year: 1860

description: Zinal mit dem Le Besso im Hintergrund
description: nach Skizze von H. Steiger Zölper ; copiert [Müller-Wegmann]
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC
Certified nurse-midwives' attitudes, beliefs, and perceptions about the use of Universal Precautions
Creators: name: Faucett, Gretchen
name: Velsmid, Stephanie
Publisher: name: University of Utah
Year: 2012
Subjects: Midwifery
Beliefs

description: The primary purpose of this descriptive correlational study was to survey the attitudes, beliefs, and perceptions about the use of Universal Precautions (UPs) by Certified Nurse-Midwives (CNMs). Data were collected using a self-report questionnaire based on the components of Azjen and Fishbein's Theory of Reasoned Action (TRA). A probability sample was used to secure a representative sample of CNMs throughout the United States. This sample reported positive attitudes about the protectiveness of UPs. The CNMs' motivation to comply with the use of UPs was influenced by their family members. However, the CNMs' own opinions regarding the use of UPs held the greatest influence. Only 5.5% of the CNMs reported using UPs 100% of the time, according to the criteria established for this study. Four of eight barriers to use of UPs were identified by the CNMs. These were that UPs affected the ability to see clearly, the intimacy of the birth process, were bothersome, and were sometimes not used out of force of habit. Correlation coefficients were found to be significant between four barriers to UP use and the CNMs' attitude, perceived behavioral control, and their subsequent use of UPs. The more positive the attitude held by the CNMs about the protectiveness of a UP item, the greater the compliance rate and the less perceived barriers there were to its use.
In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches
Creators: name: Hassab, Mahmoud A. El
name: Ibrahim, Tamer M.
name: Al-Rashood, Sara T.
name: Alharbi, Amal
name: Eskandrani, Razan O.
name: Eldehna, Wagdy M.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The novel coronavirus disease COVID-19, caused by the virus SARS CoV-2, has exerted a significant unprecedented economic and medical crisis, in addition to its impact on the daily life and health care systems all over the world. Regrettably, no vaccines or drugs are currently available for this new critical emerging human disease. Joining the global fight against COVID-19, in this study we aim at identifying a potential novel inhibitor for SARS COV-2 2′-O-methyltransferase (nsp16) which is one of the most attractive targets in the virus life cycle, responsible for the viral RNA protection via a cap formation process. Firstly, nsp16 enzyme bound to Sinefungin was retrieved from the protein data bank (PDB ID: 6WKQ), then, a 3D pharmacophore model was constructed to be applied to screen 48 Million drug-like compounds of the Zinc database. This resulted in only 24 compounds which were subsequently docked into the enzyme. The best four score-ordered hits from the docking outcome exhibited better scores compared to Sinefungin. Finally, three molecular dynamics (MD) simulation experiments for 150 ns were carried out as a refinement step for our proposed approach. The MD and MM-PBSA outputs revealed compound 11 as the best potential nsp16 inhibitor herein identified, as it displayed a better stability and average binding free energy for the ligand-enzyme complex compared to Sinefungin.
Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of Ulmus davidiana var. japonica
Creators: name: Kim, Jang Hoon
name: Park, Ji Su
name: Lee, Yun Ji
name: Choi, Sena
name: Kim, Young Ho
name: Yang, Seo Young
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A novel compound 1 and nine known compounds (2–10) were isolated by open column chromatography analysis of the root bark of Ulmus davidiana. Pure compounds (1–10) were tested in vitro to determine the inhibitory activity of the catalytic reaction of soluble epoxide hydrolase (sEH). Compounds 1, 2, 4, 6–8, and 10 had IC50 values ranging from 11.4 ± 2.3 to 36.9 ± 2.6 μM. We used molecular docking to simulate inhibitor binding of each compound and estimated the binding pose of the catalytic site of sEH. From this analysis, the compound 2 was revealed to be a potential inhibitor of sEH in vitro and in silico. Additionally, molecular dynamics (MD) study was performed to find detailed interaction signals of inhibitor 2 with enzyme. Finally, compound 2 is promising candidates for the development of a new sEH inhibitor from natural plants.
Das  Matterhorn von Breul italienische Seite
Creators: name: Rosenmund, Max
Publisher: name: [s.n.]
Year: 1877

description: gez. v. M Rosenmund ; Copie [Müller-Wegmann]
description: Aus der Sammlung Johann Müller-Wegmann; Depositum der SAC Sektion Uto in der Zentralbibliothek des SAC