cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Μελέτη σύνθεσης βενζο-2-αζεπινονών, πιθανών αναστολέων PARP-1, μέσω αντιδράσεων κυκλοπροσθήκης νιτριλοξειδίων
Creators: name: Πρίμπας, Γεώργιος Δημητρίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2021
Subjects: βενζο-2-αζεπινόνες
αναστολείς PARP-1
1,3-διπολικές κυκλοπροσθήκες με νιτριλοξείδια
benzo-2-azepinones
PARP-1 inhibitors
1,3-dipolar cycloadditions with nitriloxides

description: Η παρούσα διπλωματική εργασία εκπονήθηκε καθ’ ολοκληρίαν στο Εργαστήριο Οργανικής Χημείας του Τμήματος Χημείας του Αριστοτελείου Πανεπιστημίου Θεσσαλονίκης. Αντικείμενο της υπήρξε η μελέτη και η προσπάθεια σύνθεσης νέων πιθανών αναστολέων της PARP-1 μέσω 1,3-διπολικών κυκλοπροσθηκών. Στην εισαγωγή γίνεται αναφορά τόσο στη δομή και την καταλυτική δράση του ενζύμου PARP-1, όσο και σε πρώιμες και σύγχρονες μελέτες που οδήγησαν στη σύνθεση αναστολέων της PARP-1. Επίσης παρουσιάζονται γενικές πληροφορίες που διέπουν τις αντιδράσεις 1,3-διπολικής κυκλοπροσθήκης και κυρίως σε αυτές στις οποίες χρησιμοποιούνται ως δίπολα τα νιτριλοξείδια. Στο κύριο μέρος παρουσιάζονται αναλυτικά οι συνθετικές πορείες που ακολουθήθηκαν και ερμηνεύονται τα πειραματικά αποτελέσματα. Στο τελευταίο μέρος της εργασίας περιγράφονται λεπτομερώς οι πειραματικές διαδικασίες που ακολουθήθηκαν για την σύνθεση και απομόνωση των ενώσεων και παρατίθενται συνοπτικά τα φασματοσκοπικά τους δεδομένα
description: This Master thesis was conducted at the Laboratory of Organic Chemistry, at the Department of Chemistry of the Aristotle University of Thessaloniki. Main goal of this scientific research was the design and the attempt of synthesis of a novel potential inhibitor of PARP-1 using as a key reaction the 1,3-dipolar cycloaddition. In the introduction are described the structure and the catalytic role of PARP-1 enzyme, as well as, the development of PARP-1 inhibitors that have been designed by other scientific groups. Furthermore, some general information about 1,3-dipolar cycloadditions with nitriloxides are given. The main part of the study contains all the synthetic schemes that were designed and followed step by step, including the problems faced and troubleshooting, for the attempt of synthesis of a novel potential PARP-1 inhibitor. In the last part of this study, all experimental procedures are described in every detail. Also, the spectral data of all compounds synthesized are given, whereas all references are listed at the last pages of this manuscript
Spacetime decay of cones at strong coupling
Creators: name: Gregory, Ruth
name: Harvey, Jeff
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study time dependent solutions in dilaton gravity which correspond to the decay of conical spacetimes. In string theory this can be interpreted as a strong coupling limit of the decay of a non-supersymmetric orbifold spacetime with localized tachyons.
description: 9 pages LaTeX (JHEP3), 2 figures, acknowledgements amended
Density of states approach for lattice gauge theory with a $θ$-term
Creators: name: Gattringer, Christof
name: Orasch, Oliver
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We discuss a new strategy for treating the complex action problem of lattice field theories with a $θ$-term based on density of states (DoS) methods. The key ingredient is to use open boundary conditions where the topological charge is not quantized to integers and the density of states is sufficiently well behaved such that it can be computed precisely with recently developed DoS techniques. After a general discussion of the approach and the role of the boundary conditions, we analyze the method for 2-d U(1) lattice gauge theory with a $θ$-term, a model that can be solved in closed form. We show that in the continuum limit periodic and open boundary conditions describe the same physics and derive the DoS, demonstrating that only for open boundary conditions the density is sufficiently well behaved for a numerical evaluation. We conclude our proof of principle analysis with a small test simulation where we numerically compute the density and compare it with the analytical result.
description: Reference added; slight change of title. Final version to appear in Nuclear Physics B
Total Food Expenditures: An Update on the Revised Series
Creators: name: Manchester, Alden C.
name: Belongia, Mike
name: Manchester, Alden C.
name: Belongia, Mike
Publisher: name: Unknown
Year: 1980
Subjects: Consumer/Household Economics

description: A new measure of U.S. food expenditures, called the total expenditures (TE) series, was developed w reconcile the conceptual differences between two other widely used measures of food expenditures.' The TE accounts bridge the conceptual differences between the personal consumption expenditures (PCE) estimated by the U.S. Department of Commerce, Bureau of Economic Analysis, and the marketing bill series published by the Economics, Statistics, and Cooperatives Service (ESCS), USDA.
Are Coronae of Magnetically Active Stars Heated by Flares? III. Analytical Distribution of Superimposed Flares
Creators: name: Arzner, K.
name: Guedel, M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: (abridged) We study the hypothesis that observed X-ray/extreme ultraviolet emission from coronae of magnetically active stars is entirely (or to a large part) due to the superposition of flares, using an analytic approach to determine the amplitude distribution of flares in light curves. The flare-heating hypothesis is motivated by time series that show continuous variability suggesting the presence of a large number of superimposed flares with similar rise and decay time scales. We rigorously relate the amplitude distribution of stellar flares to the observed histograms of binned counts and photon waiting times, under the assumption that the flares occur at random and have similar shapes. Applying these results to EUVE/DS observations of the flaring star AD Leo, we find that the flare amplitude distribution can be represented by a truncated power law with a power law index of 2.3 +/- 0.1. Our analytical results agree with existing Monte Carlo results of Kashyap et al. (2002) and Guedel et al. (2003). The method is applicable to a wide range of further stochastically bursting astrophysical sources such as cataclysmic variables, Gamma Ray Burst substructures, X-ray binaries, and spatially resolved observations of solar flares.
description: accepted for publication in ApJ
Additional file 1 of Orthologous promoters from related methylotrophic yeasts surpass expression of endogenous promoters of Pichia pastoris
Creators: name: Vogl, Thomas
name: Fischer, Jasmin
name: Hyden, Patrick
name: Wasmayer, Richard
name: Sturmberger, Lukas
name: Glieder, Anton
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Supporting information including S1 (primer sequences), S2 (promoter alignments), S3 (screening data), and S4 (list of plasmids and strains).
Nutrient Content of the National Food Supply
Creators: name: Marston, Ruth M.
name: Peterkin, Betty B.
name: Marston, Ruth M.
name: Peterkin, Betty B.
Publisher: name: Unknown
Year: 1980
Subjects: Food Consumption/Nutrition/Food Safety

description: Although Americans are often admonished for eating too much-especially fats and sugars-the National Food Supply Statistics' indicate that such advice, being ignored. The caloric and most nutrient levels of the U.S. diet are the same or higher than last year and 10 years ago.' Furthermore, consumption of sugars in 1979 is the highest ever recorded-213 grams of carbohydrate and 850 calories per person per day.
Commemorative monuments in Rome (1870-1911)
Creators: name: Chaves, Miguel-Ángel
Publisher: name: CAP - Public Art Journal
Year: 2020

description: In 1870 Rome became part of the unified kingdom of Italy, becoming from that moment the capital of the new State. The city entered a new phase of its history that historiography has called the “Terza Roma” (Third Rome), or “Roma Capitale”, to differentiate it from the “Prima Rome” (the First Rome, the Rome of the Caesars) and the “Seconda Roma” (the Second Rome, the Rome of the Popes). While the first two always had the prominence proper to their importance in the history of architecture and urban planning, the new Roma Capitale also builds its image through a complete and perfectly planned programme of actions, among which the proliferation of commemorative monuments in the public space stands out, with which to contribute to the construction of the image of modern Rome. The permanence in time of these values, and also of their transformations, appreciation and new meanings, enrich and update the relationships between art, heritage, city and communication.
description: CAP - Public Art Journal, Vol 2 No 2 (2020): Public Art Research, aims and networks
Thermally activated diffusion and lattice relaxation in (Si)GeSn materials
Creators: name: Driesch, Nils von den
name: Wirths, Stephan
name: Troitsch, Rene
name: Mussler, Gregor
name: Breuer, Uwe
name: Moutanabbir, Oussama
name: Grützmacher, Detlev
name: Buca, Dan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Germanium-Tin (GeSn) alloys have emerged as a promising material for future optoelectronics, energy harvesting and nanoelectronics owing to their direct bandgap and compatibility with existing Si-based electronics. Yet, their metastability poses significant challenges calling for in-depth investigations of their thermal behavior. With this perspective, this work addresses the interdiffusion processes throughout thermal annealing of pseudomorphic GeSn binary and SiGeSn ternary alloys. In both systems, the initially pseudomorphic layers are relaxed upon annealing exclusively via thermally induced diffusional mass transfer of Sn. Systematic post-growth annealing experiments reveal enhanced Sn and Si diffusion regimes that manifest at temperatures below 600°C. The amplified low-temperature diffusion and the observation of only subtle differences between binary and ternary hint at the unique metastability of the Si-Ge-Sn material system as the most important driving force for phase separation.
description: 15 pages, 3 figures
Scaling of Entropic Shear Rigidity
Creators: name: Xing, Xiangjun
name: Mukhopadhyay, Swagatam
name: Goldbart, Paul M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The scaling of the shear modulus near the gelation/vulcanization transition is explored heuristically and analytically. It is found that in a dense melt the effective chains of the infinite cluster have sizes that scale sub-linearly with their contour length. Consequently, each contributes k_B T to the rigidity, which leads to a shear modulus exponent dν. In contrast, in phantom elastic networks the scaling is linear in the contour length, yielding an exponent identical to that of the random resistor network conductivity, as predicted by de Gennes'. For non-dense systems, the exponent should cross over to dνwhen the percolation length becomes much larger than the density-fluctuation length.
description: 4 pages, 2 eps figures
Food Consumption in 1979
Creators: name: Moore, Patricia A.
name: Moore, Patricia A.
Publisher: name: Unknown
Year: 1980
Subjects: Food Consumption/Nutrition/Food Safety

description: Significant changes in the 1979 food consumption pattern were caused not only by economic conditions and weather variations, but also by nutritional values and cyclical changes in beef production. The greatest substitutions occurred among beef, pork, and poultry consumption.
Insights for the endorsement of a holistic approach for public sculpture research
Creators: name: Moreira, Patricia
name: Vieira, Eduarda
name: Abreu, José G.
Publisher: name: CAP - Public Art Journal
Year: 2020

description: This article reflects on the holistic approach for public sculpture research within the BIONANOSCULP project, focusing on the reasons behind the project development, its objectives, selected achievements and future outcomes. Focusing on one of the seven selected sculptures that were studied within the project, “Afonso de Albuquerque”, the reasons behind the selection of these public art works, their historical study, a critical assessment of their significance and conservation status are discussed. A brief description of the most significant analytical innovations of the project and insight on the future of sustainable conservation is presented.
description: CAP - Public Art Journal, Vol 2 No 2 (2020): Public Art Research, aims and networks
The Optimal Allocation of Global Land Use in the Food-Energy-Environment Trilemma
Creators: name: Steinbuks, Jevgenijs
name: Hertel, Thomas W.
name: Steinbuks, Jevgenijs
name: Hertel, Thomas W.
Publisher: name: Unknown
Year: 2012
Subjects: Land Economics/Use

description: This study analyzes the optimal allocation of the world's land resources over the course of the next century in the dynamic forward-looking framework, which brings together distinct strands of economic, agronomic, and biophysical literature and incorporates key drivers affecting global land use. We show that, while some deforestation is optimal in the near term, the desirability of further deforestation is limited by mid-century under the baseline scenario. While the adverse productivity shocks from climate change have a modest effect on global land use, when combined with high growth in energy prices they lead to significant deforestation and higher GHG emissions than in the baseline. Imposition of GHG emissions constraint further heightens the competition for land, as fertilizer use declines and land-based mitigation strategies expand. However, the effectiveness of such a pre-announced constraint is completely diluted by inter temporal substitution of deforestation which accelerates prior to imposition of the target.
Solid accretion onto planetary cores in radiative disks
Creators: name: Zormpas, Apostolos
name: Picogna, Giovanni
name: Ercolano, Barbara
name: Kley, Wilhelm
Publisher: name: arXiv
Year: 2020
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The solid accretion rate, necessary to grow gas giant planetary cores within the disk lifetime, has been a major constraint for theories of planet formation. We tested the solid accretion rate efficiency on planetary cores of different masses embedded in their birth disk, by means of 3D radiation-hydrodynamics, where we followed the evolution of a swarm of embedded solids of different sizes. We found that using a realistic equation of state and radiative cooling, the disk at 5 au is able to cool efficiently and reduce its aspect ratio. As a result, the pebble isolation mass is reached before the core grows to 10 Earth masses, stopping efficiently the pebble flux and creating a transition disk. Moreover, the reduced isolation mass halts the solid accretion before the core reaches the critical mass, leading to a barrier to giant planet formation, and it explains the large abundance of super-Earth planets in the observed population.
description: Published in A&A, 8 pages, 9 figures
Prediction of a new class of half-metallic antiferromagnets
Creators: name: Kodderitzsch, D.
name: Hergert, W.
name: Szotek, Z.
name: Temmerman, W. M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report on vacancy induced half-metallicity in the prototype Mott-insulating substances MnO and NiO. By embedding a cation-vacancy into a magnetic system a new road opens up to the construction of half-metallic antiferromagnets. For Ni$_{0.97}$O we find a half-metallic antiferromagnet a system hitherto only proposed for complicated crystal structures.
description: 4 pages, 4 figures and 1 table
The Role of Irrigation in Determining the Global Land Use Impacts of Biofuels
Creators: name: Taheripour, Farzad
name: Hurtle, Thomas W.
name: Liu, Jing
name: Taheripour, Farzad
name: Hurtle, Thomas W.
name: Liu, Jing
Publisher: name: Unknown
Year: 2011
Subjects: Land Economics/Use

description: In recent years there has been a flurry of activity aimed at evaluating the land use consequences of biofuels programs and the associated carbon releases. In this paper we argue that these studies have tended to underestimate the ensuing land use emissions, because they have ignored the role of irrigation, and associated constraints on cropland expansion. In this paper, we develop a new general equilibrium model which distinguishes irrigated and rain fed cropping industries at a global scale. Using the new model we evaluate the implications of land use change due to US ethanol programs, in the context of physical constraints on the expansion of irrigated cropland. We find that models which mingle irrigated and rain fed areas underestimate the global land use changes induced due to the US ethanol expansion by about 5.7%. They tend to underestimate the corresponding land use emissions by more than one fifth.
Global Applied General Equilibrium Analysis using the GTAP Framework
Creators: name: Hertel, Thomas W.
name: Hertel, Thomas W.
Publisher: name: Unknown
Year: 2012
Subjects: subject: International Relations/Trade
subject: Domestic policy analysis
subject: Trade and the environment
subject: European Union
subject: Common Wealth of Independent States

description: This chapter provides an overview of the first two decades of the Global Trade Analysis Project (GTAP) - an effort to support a standardized data base and CGE modeling platform for international economic analysis. It characterizes GTAP in four different dimensions: institutional innovation, a network, a database and a standardized modeling platform. Guiding principles for the GTAP modeling framework include flexibility, ease of use, transparency, and symmetric treatment of production and utility fundamentals across regions. The chapter reviews core modeling assumptions relating to the regional household, private consumption behavior, welfare decomposition, the "global bank", treatment of the international trade and transport sector, and imports. Model validation and sensitivity analysis, as well as software issues receive attention as well. The chapter also offers brief overviews of the two major areas of application: international economic integration and global environmental issues. It closes with a discussion of future directions for the Project.
Study of the Gauge Mediation Signal with Non-pointing Photons at the CERN LHC
Creators: name: Kawagoe, Kiyotomo
name: Kobayashi, Tomio
name: Nojiri, Mihoko M.
name: Ochi, Atsuhiko
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper we study the gauge mediation signal with the ATLAS detector at the CERN LHC. We focus on the case where the NLSP is the long-lived lightest neutralino ($\tildeχ^0_1$) which decays dominantly into a photon ($γ$) and a gravitino ($\tilde{G}$). A non-pointing photon from the neutralino decay can be detected with good position and time resolutions by the electormagnetic calorimeter (ECAL), while the photon momentum would be precisely measured if the photon is converted inside the inner tracking detector before reaching the ECAL. A new technique is developed to determine the masses of the slepton ($\tilde{\ell}$) and the neutralino from events with a lepton and a converted non-pointing photon arising from the cascade decay $\tilde{\ell}\to \ell\tildeχ^0_1\to \ellγ\tilde{G}$. A Monte Carlo simulation at a sample point shows that the masses would be measured with an error of 3% for $\cal{O}$(100) selected $\ellγ$ pairs. Once the sparticle masses are determined by this method, the decay time and momentum of the neutralino are solved using the ECAL data and the lepton momentum only, for all $\ellγ$ pairs without the photon conversion. We estimate the sensitivity to the neutralino lifetime for $cτ=10$ cm to $\cal{O}$(10) m.
description: 19 page, 7 figures, revtex
Breather Solutions of the Cubic Klein-Gordon Equation
Creators: name: Scheider, Dominic
Publisher: name: arXiv
Year: 2020
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35L71, 35B32 (Primary) 35B10, 35J05 (Secondary)

description: We obtain real-valued, time-periodic and radially symmetric solutions of the cubic Klein-Gordon equation \begin{align} \partial_t^2 U - ΔU + m^2 U = Γ(x) U^3 \quad \text{on } \mathbb{R} \times \mathbb{R}^3, \end{align} which are weakly localized in space. Various families of such "breather" solutions are shown to bifurcate from any given nontrivial stationary solution. The construction of weakly localized breathers in three space dimensions is, to the author's knowledge, a new concept and based on the reformulation of the cubic Klein-Gordon equation as a system of coupled nonlinear Helmholtz equations involving suitable conditions on the far field behavior.
description: Part of author's dissertation thesis (DOI below)
Performative Materials and Activist Commemoration.
Creators: name: Widrich, Mechtild
Publisher: name: CAP - Public Art Journal
Year: 2020

description: Monument debates in the second decade of the twenty-first century, turning almost entirely on questions of who is represented and by whom, might benefit from considering questions of how and with what material resources first raised in the context of post-WWII commemoration of the Holocaust and other traumatic events. The involvement of audiences in the memorial’s physical substance, entering its spaces and otherwise performing acts of commemoration rather than just looking upon public art meant to broadcast an ideal official history, has been central to the most durable memorials of the last half century, and is given a particularly radical turn by artist interested in justice and restitution. In Colombia, Doris Salcedo has taken the very fabrication of a memorial space—made from surrendered FARC firearms by women who had suffered in the war in cathartic acts of hammering sheet metal—as a performative process making commemoration physical. The same phenomena can be observed spontaneously in acts of public imagination directed at more conventional memorial objects, such as the Korean Statue for Peace, whose bronze girl commemorates the victims of sexual exploitation during WWII is clothed by anonymous contemporary Koreans. The task for theorists of monumentality today, as much as for monument-makers, is to understand how an ethics of care can meet and interact forcefully with a politics of taking responsibility.
description: CAP - Public Art Journal, Vol 2 No 1 (2020): Sculpture: Studies
The Black Hole Singularity in AdS/CFT
Creators: name: Fidkowski, Lukasz
name: Hubeny, Veronika
name: Kleban, Matthew
name: Shenker, Stephen
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We explore physics behind the horizon in eternal AdS Schwarzschild black holes. In dimension d >3, where the curvature grows large near the singularity, we find distinct but subtle signals of this singularity in the boundary CFT correlators. Building on previous work, we study correlation functions of operators on the two disjoint asymptotic boundaries of the spacetime by investigating the spacelike geodesics that join the boundaries. These dominate the correlators for large mass bulk fields. We show that the Penrose diagram for d>3 is not square. As a result, the real geodesic connecting the two boundary points becomes almost null and bounces off the singularity at a finite boundary time t_c \neq 0. If this geodesic were to dominate the correlator there would be a "light cone" singularity at t_c. However, general properties of the boundary theory rule this out. In fact, we argue that the correlator is actually dominated by a complexified geodesic, whose properties yield the large mass quasinormal mode frequencies previously found for this black hole. We find a branch cut in the correlator at small time (in the limit of large mass), arising from coincidence of three geodesics. The t_c singularity, a signal of the black hole singularity, occurs on a secondary sheet of the analytically continued correlator. Its properties are computationally accessible. The t_c singularity persists to all orders in the 1/m expansion, for finite α', and to all orders in g_s. Certain leading nonperturbative effects can also be studied. The behavior of these boundary theory quantities near t_c gives, in principle, significant information about stringy and quantum behavior in the vicinity of the black hole singularity.
description: 49 pages, 6 appendices, 14 figures. v3: typos fixed
Reorientation in Antiferromagnetic Multilayers: Spin-Flop Transition and Surface Effects
Creators: name: Roessler, U. K.
name: Bogdanov, A. N.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Nanoscale superlattices with uniaxial ferromagnetic layers antiferromagnetically coupled through non-magnetic spacers are recently used as components of magnetoresistive and recording devices. In the last years intensive experimental investigations of these artificial antiferromagnets have revealed a large variety of surface induced reorientational effects and other remarkable phenomena unknown in other magnetic materials. In this paper we review and generalize theoretical results, which enable a consistent description of the complex magnetization processes in antiferromagnetic multilayers, and we explain the responsible physical mechanism. The general structure of phase diagrams for magnetic states in these systems is discussed. In particular, our results resolve the long standing problem of a ``surface spin-flop'' in antiferromagnetic layers. This explains the different appearance of field-driven reorientation transitions in systems like Fe/Cr (001) and (211) superlattices, and in [CoPt]/Ru multilayers with strong perpendicular anisotropy.
description: Companion paper for talk at Second Seeheim Conference on Magnetism, June 27- July 1, 2004; 8 pages included 7 figures
Μελέτη της εξέλιξης του τρόπου διαχείρισης των κλινικών δεδομένων στο διάστημα προ της πανδημίας και κατά τη διάρκεια αυτής
Creators: name: Βαντσιώτη, Αικατερίνα Νικολάου
Publisher: name: Aristotle University of Thessaloniki
Year: 2021
Subjects: Κλινικές μελέτες
Πρωτόκολλο
Διαχείριση δεδομένων
Clinical trials
Protocol
Data management

description: Η πορεία σχεδιασμού και ανάπτυξης ενός νέου φαρμάκου ή ιατροτεχνολογικού προϊόντος, αποτελεί μία πολύπλοκη και δαπανηρή διαδικασία, το μεγαλύτερο μέρος της οποίας περιλαμβάνει τη διεξαγωγή κλινικών μελετών. Στις κλινικές μελέτες εξετάζεται η χορήγηση του υπό μελέτη φαρμάκου σε υγιείς και ασθενείς εθελοντές προκειμένου να παρατηρηθεί αν η φαρμακοκινητική και φαρμκοδυναμική του συμπεριφορά είναι οι προβλεπόμενες και αν προκύπτουν μη αναμενόμενες σοβαρές ανεπιθύμητες ενέργειες. Όλες οι διαδικασίες που διεξάγονται κατά τη διάρκεια των κλινικών μελετών –από την ένταξη των εθελοντών συμμετεχόντων μέχρι και τις διαδικασίες της συνήθους κλινικής πρακτικής-ορίζονται από το πρωτόκολλο που συντάσσεται από την ερευνητική ομάδα και εγκρίνεται από ανεξάρτητο οργανισμό. Στην παρούσα ερευνητική εργασία, απευθυνόμενοι μέσω ερωτηματολογίου σε επιστήμονες υγείας που συμμετέχουν ή έχουν συμμετάσχει σε κλινικές μελέτες, μελετήσαμε τα μέσα με τα οποία έχουν πρόσβαση στο πρωτόκολλο, τον τρόπο με τον οποίο διαχειρίζονται το ίδιο αλλά και τα δεδομένα που προκύπτουν και αν η πανδημία του κορωνοϊού επηρέασε αισθητά τις διαδικασίες αυτές
description: Designing and development of a new drug or medical device, considered to be a complicated and expensive procedure, including clinical trials. Conducting clinical trials to human subjects, contributes understanding the pharmacokinetic and pharmacodynamic characteristics of the drug and revealing any unexpectable adverse events. Any procedure that takes place during a trial as well as the way that a new participant can enter the trial, are fully described in trial’s protocol. The content of the protocol is written by the research team and approved by an independent review board. Specifically referring to this study, we have designed a questionnaire which was answered by researchers who have participated at least once, in a clinical trial. According to their answers we concluded how they prefer to study the protocol, which device is more preferable, how they manage the trial’s data and if the covid pandemic has affected the above
Letter on statuary and power. Statues as political statements
Creators: name: Abreu, José G.
Publisher: name: CAP - Cadernos de Arte Pública / Public Art Journal
Year: 2020

description: Statuary, statue and statute all derive from the Latin verb statuere, meaning “to cause, to stand, to set up”, whose root comes from the nom status, meaning “standing, position”. However, if we decide to look for even older origins, we will find out that all these words derive from the Proto-Indo-European root stā-, meaning “to stand, set down, make or be firm".
description: CAP - Cadernos de Arte Pública / Public Art Journal, Vol 2 No 2 (2020): Public Art Research, aims and networks
Level Curvature distribution in a model of two uncoupled chaotic subsystems
Creators: name: Ergun, Guler
name: Fyodorov, Yan V.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We study distributions of eigenvalue curvatures for a block diagonal random matrix perturbed by a full random matrix. The most natural physical realization of this model is a quantum chaotic system with some inherent symmetry, such that its energy levels form two independent subsequences, subject to a generic perturbation which does not respect the symmetry. We describe analytically a crossover in the form of a curvature distribution with a tunable parameter namely the ratio of inter/intra subsystem coupling strengths. We find that the peak value of the curvature distribution is much more sensitive to the changes in this parameter than the power law tail behaviour. This observation may help to clarify some qualitative features of the curvature distributions observed experimentally in acoustic resonances of quartz blocks.
description: 22 pages, 2 new eps figures, uses revtex4. To appear in Phys. Rev. E
Constant vorticity geophysical waves with centripetal forces and at arbitrary latitude
Creators: name: Chu, Jifeng
name: Yang, Yanjuan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Analysis of PDEs (math.AP)
subject: Dynamical Systems (math.DS)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We consider three-dimensional geophysical flows at arbitrary latitude and with constant vorticity beneath a wave train and above a flat bed in the $β$-plane approximation with centripetal forces. We consider the $f$-plane approximation as well as the $β$-plane approximation. For the $f$-plane approximation, we prove that there is no bounded solution. For the $β$-plane approximation, we show that the flow is necessarily irrotational and the free surface is necessarily flat if it exhibits a constant vorticity. Our results reveal some essential differences from those results in the literature, due to the presence of centripetal forces. Moreover, for the case exhibiting the surface tension, we prove that there are no flows exhibiting constant vorticity.
Non-unitary evolutions of noncommutative worlds with symmetry
Creators: name: Sasakura, Naoki
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Motivated by describing time-evolutions of noncommutative worlds, I discuss symmetry-preserving evolutions of noncommutative worlds of finite dimensional representation spaces. An interesting issue in such evolutions is that there can be transitions of representation spaces of symmetry, and therefore the evolutions are generally non-unitary or symmetry-violating. The central idea of this paper is that a main world evolves by emitting baby worlds which compensate the violations of the symmetry of the main world. Tracing out the states of the baby worlds, the symmetry-preserving evolutions of the density matrices of the main world are obtained. I give a simple example with SU(2) symmetry, which can be regarded as an evolving quantum two-sphere. This simple model has some attractive features resembling our universe: it gets born from a vacuum and its entropy of geometric origin grows. I also discuss the evolutions in Heisenberg picture.
description: 10 pages, 2 figures, LaTeX
Introduction to the Global Trade Analysis Project and the GTAP Data Base
Creators: name: Walmsley, Terrie L.
name: Aguiar, Angel H.
name: Narayanan, Badri
name: Walmsley, Terrie L.
name: Aguiar, Angel H.
name: Narayanan, Badri
Publisher: name: Unknown
Year: 2012
Subjects: subject: International Relations/Trade
subject: The GTAP Data Base and extensions

description: The Global Trade Analysis Project (GTAP) is a global network of researchers and policy makers conducting quantitative analysis of international policy issues. The motivation and ultimate success of the Project stems from the fact that collaboration is essential for detailed analysis of the global economy. The importance of collaboration to improve the quality of policy analysis world-wide is most clearly seen in the development of the GTAP Data Base. The GTAP Data Base is the centerpiece of the Global Trade Analysis Project. It records the annual flows of goods and services for the entire world economy in the benchmark year(s). It consists of bilateral trade, transport, and protection matrices that link individual country/regional economic data bases. The production of the GTAP Data Base relies on the valuable contributions of many individuals and organizations throughout the world. Individuals contribute the best available input-output table for their country, while other experts contribute the macro, trade, protection and other data required. The Center for Global Trade Analysis, the home of GTAP, then brings these contributions together into one useable, globally consistent, database. The result is a fully documented , publicly available and regularly updated global database. This year (2012), the eighth version of the GTAP Data Base was released, covering 129 countries, 57 sectors, 5 factors and two base years (2004 and 2007). The GTAP Data Base is utilized in a suite of comparative static and dynamic computable general equilibrium models and underlies most contemporary economic analysis of global policy issues related to trade, energy and the environment.
The 16O(e,e'pp)14C reaction to discrete final states
Creators: name: Ryckebusch, J.
name: Van Nespen, W.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Differential cross sections for exclusive 16O(e,e'pp)14C processes are computed within a distorted-wave framework which includes central short-range correlations and intermediate Δ+ excitations. The cross sections are compared to high-resolution data from the MAMI facility at Mainz for a central energy and momentum transfer of ω=215 MeV and q=316 MeV respectively. A fair agreement between the numerical calculations and data is reached when using spectroscopic information extracted from a 15N(d,3He)14C experiment. The comparison between the calculations and the data provides additional evidence that short-range correlations exclusively affect nucleon pairs with a small center-of-mass momentum residing in a relative S state.
description: 7 pages, 6 figures
Η έννοια του θανάτου στον άγιο Μάξιμο τον Ομολογητή
Creators: name: Χριστόπουλος, Παύλος Αθανασίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2021
Subjects: Μάξιμος Ομολογητής
Θάνατος
Πατερική Γραμματεία
Maximus the Confessor
Death
Orthodox Fathers

description: Αφορμή της παρούσης έρευνας αποτέλεσε η ανάγκη για εμβάθυνση στην Πατερική Γραμματεία και κατά συνέπεια και πιο συγκεκριμένα ο σκοπός της είναι η ανάδειξη της οπτικής του αγίου Μαξίμου του Ομολογητού για το θέμα του θανάτου. Μελετώντας κανείς τα γραπτά του αγίου, αντιλαμβάνεται πως όχι μόνο δεν υπάρχουν γενικοί και επιγραμματικοί ορισμοί για το συγκεκριμένο ζήτημα αλλά η εκμαίευση απαντήσεων πηγάζει από μια σφαιρική ανάγνωση υπό το πρίσμα όλης της ιστορικής πορείας του ανθρώπου. Κατ’ επέκταση αναφερθήκαμε στα τρία στάδια της ιστορίας ως τις αντίστοιχες θεματικές: Δημιουργία – Πτώση – Απολύτρωση. Στο Πρώτο Κεφάλαιο αναλύσαμε το Δημιουργικό σχέδιο του Θεού και τον σκοπό του ανθρώπου μέσα στην κτίση κάνοντας αναφορά για τους λόγους των όντων, την έννοια της κίνησης αλλά και την οντολογία του ανθρώπου. Ουσιαστικά, στο Κεφάλαιο αυτό, τοποθετήσαμε όλες εκείνες τις σταθερές σχετικά με την Δημιουργία ως δεδομένα για την ανθρώπινη πραγματικότητα. Το Δεύτερο Κεφάλαιο μελετήσαμε την κατάσταση του ανθρώπου προπτωτικά, την αστοχία του με το αμάρτημα του Αδάμ καθώς και την κατάσταση που ακολούθησε αυτής της παραβάσεως. Στο Τρίτο Κεφάλαιο ασχοληθήκαμε με την Χριστολογία του αγίου Μαξίμου και γιατί αποτελεί τόσο σημαντικό θέμα η αποσαφήνισή της, το μυστήριο της Ενσάρκου Οικονομίας και παράλληλα, την Εκκλησία ως τόπο και τρόπο με τον οποίο μπορεί ο πιστός να πορευθεί σύμφωνα με την φύση του. Έτσι, εξετάσαμε το ζήτημα του θανάτου συλλογικά μέσα από την θεολογική σκέψη του αγίου Μαξίμου
description: The occasion of this research was a personal need for deepening in the thoughts of the Fathers and consequently and more specifically the purpose is to highlight the view of St. Maximus the Confessor on the issue of death. If someone look closer in the writings of the Saint, realizes that not only there is no general and epigrammatic definitions for this topic but the extraction of answers emerges from a general reading in the light the whole historical line of Man. As a result, we mentioned the three stages of History as the corresponding themes: Creation – Fall – Redemption. In the First Chapter we analyzed the Creative plan of God and the purpose of man in creation, making reference to the logoi of beings, the meaning of movement and the ontology of man. Essentially, in this Chapter, we have placed all those constants about Creation as facts about human reality. In the Second Chapter we studied the condition of man before the Fall, his failure because of Adam’ s sin and the situation that followed this transgression. In the Third Chapter we focused on the Christology of St. Maximus and why is so important, the mystery of Incarnate Economy and also, the Church as the place and the way with which the believer can walk according to his nature. Thus, we examined the issue of death collectively through the theological thought of St. Maximus
title: Using Artificial Intelligence for Disaster Management Providing Relief
Creators: name: Upadhyay , Niteesh Kumar
name: Mahak , Rathee
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2020

description: (1) Galgotias University, India; (2) Supreme Court of India

We have seen drastic growth of Artificial Intelligence in the past few years and what seemed to be a distant dream earlier is now becoming a reality. Though there are a lot of debates on Artificial Intelligence and its use, its legality and much more but Artificial Intelligence can prove to be an asset in the field of Disaster Management and providing relief. There have been many instances wherein a lot of loss in terms of human lives, property and economy of the nation is being caused because of a disaster and it takes time to analyse the situation and provide relief.
Data Driven Transfer Functions and Transmission Network Parameters for GIC Modelling
Creators: name: Heyns, M. J.
name: Gaunt, C. T.
name: Lotz, S. I.
name: Cilliers, P. J.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Space Physics (physics.space-ph)
subject: Systems and Control (eess.SY)
subject: FOS: Physical sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Typical geomagnetically induced current (GIC) modelling assumes the induced quasi-DC current at a node in the transmission network is linearly related to the local geoelectric field by a pair of network parameters. Given a limited time-series of measured geomagnetic and GIC data, an empirical method is presented that results in a statistically significant generalised ensemble of parameter estimates with the error in the estimates identified. The method is showcased for different transmission networks and geomagnetic storms and, where prior modelling exists, shows improved GIC estimation. Furthermore, modelled networks can be locally characterised and probed without any further network knowledge. Insights include network parameter variation, effective network directionality and response. Merging the network parameters and geoelectric field estimation, a transfer function is derived which offers an alternative approach to assessing transformer exposure to GICs.
description: 8 pages, 8 figures, accepted for PSCC 2020
Competition for Land in the Global Bioeconomy
Creators: name: Hertel, Thomas
name: Steinbuks, Jevgenjs
name: Baldos, Uris
name: Hertel, Thomas
name: Steinbuks, Jevgenjs
name: Baldos, Uris
Publisher: name: Unknown
Year: 2012
Subjects: subject: Resource /Energy Economics and Policy
subject: Climate change policy
subject: Bioenergy
subject: Dynamic modeling

description: The global land use implications of biofuel expansion have received considerable attention in the literature over the past decade. Model-based estimates of the emissions from cropland expansion have been used to assess the environmental impacts of biofuel policies. And integrated assessment models have estimated the potential for biofuels to contribute to greenhouse gas abatement over the coming century. All of these studies feature, explicitly or implicitly, competition between biofuel feed stocks and other land uses. However, the economic mechanisms governing this competition, as well as the contribution of biofuels to global land use change, have not received the close scrutiny that they deserve. The purpose of this paper is to offer a deeper look at these factors. We begin with a comparative static analysis which assesses the impact of exogenously specified forecasts of biofuel expansion over the 2006-2035 period. Global land use change is decomposed according to the three key margins of economic response: extensive supply, intensive supply, and demand. Under the International Energy Agency's "New Policies" scenario, biofuels account for nearly one-fifth of global land use change over the 2006-2035 period. The paper also offers a comparative dynamic analysis which determines the optimal path for first and second generation biofuels over the course of the entire 21st century. In the absence of GHG regulation, the welfare-maximizing path for global land use allocates 170 Mha to biofuel feed stocks by 2100, with the associated biofuels accounting for about 30% of global liquid fuel consumption. This area expansion is somewhat diminished by expected climate change impacts on agriculture, while it is significantly increased by a moderately aggressive GHG emissions target and by advances in conversion efficiency of second generation biofuels.
Implications of Agricultural Productivity for Global Cropland Use and GHG Emissions: Borlaug vs. Jevons
Creators: name: Hertel, Thomas W.
name: Hertel, Thomas W.
Publisher: name: Unknown
Year: 2012
Subjects: subject: Productivity Analysis
subject: Baseline development
subject: Calibration and parameter estimation
subject: Model validation
subject: Climate impacts
subject: Land use
subject: Technological change
subject: Other data bases and data issues

description: This paper introduces a general framework for analyzing the impacts of regional and global technological change on long run agricultural output, prices, land rents, land use, and associated GHG emissions. In so doing, it facilitates a reconciliation of the apparently conflicting views of the impacts of agricultural productivity growth on global GHG emissions and environmental quality. As has been previously recognized, in the case of a global change in farm productivity, the critical condition for an innovation to lead to diminished land use is that the farm level demand for agricultural products is inelastic. However, in the more common case where the innovation is regional in nature, the necessary condition for a reduction in global land use and associated GHG emissions is more complex and depends on the relative yields, emissions efficiencies and supply conditions in the affected and unaffected regions. While innovations in agricultural are most common land-sparing at global scale, innovations in regions commanding a small share of global production, with relatively low yields, high land supply elasticities and low emissions efficiencies can lead to an increase in global land use change emissions. A numerical example illustrates these points and suggests that these conditions may hold for productivity shocks in Latin America and Sub-Saharan Africa. These insights are also relevant for the emerging literature on the effect of adverse climate change on global agriculture and associated emissions from land use change.
Growth of superconducting Sm(O,F)BiS2 single crystals
Creators: name: Kinami, Koki
name: Hanada, Yuji
name: Nagao, Masanori
name: Miura, Akira
name: Goto, Yosuke
name: Maruyama, Yuki
name: Watauchi, Satoshi
name: Takano, Yoshihiko
name: Tanaka, Isao
Publisher: name: arXiv
Year: 2019
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Superconducting Sm(O,F)BiS2 single crystals were successfully grown using KI-KCl flux. The obtained single crystals were flat-shaped and their size was 500um. The structure and composition of the obtained single crystals were obtained using X-ray diffraction and X-ray spectroscopy. The lattice constants of the obtained Sm(O,F)BiS2 single crystals were evaluated to be a = 3.9672(4) A and c = 13.417(6) A, while their F/(O + F) molar ratio was approximately 0.17. The superconducting transition temperature of the obtained Sm(O,F)BiS2 single crystals was 4.8 K. This was different from the reported Sm(O,F)BiS2 with no superconducting transition above 2 K. The superconducting anisotropies of the upper critical field and effective mass model of the obtained Sm(O,F)BiS2 single crystals were estimated to be approximately 26 and 10, respectively.
description: 22 pages, 7 figures