Additional file 1 of Role of surgery in T4N0-3M0 esophageal cancer
Creators: name: Qi, Chen
name: Hu, Liwen
name: Zhang, Chi
name: Wang, Kang
name: Qiu, Bingmei
name: Yi, Jun
name: Shen, Yi
Publisher: name: figshare
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Hematology

description: Additional file 1: Supplementary Table S1. Selection procedure of study cohort. Supplementary Table S2. Univariable and multivariable Cox regression analysis comparing no surgery with surgery for the OS of AJCC 8th T4aN0-3M0 EC patients. Supplementary Table S3. Univariable and multivariable Cox regression analysis comparing no surgery with surgery for the OS of AJCC 8th T4bN0-3M0 EC patients. Supplementary Table S4. Univariable and multivariable Cox regression analysis comparing no surgery with neoadjuvant therapy plus surgery for the OS of AJCC 8th T4N0-3M0 EC patients. Supplementary Table S5. Univariable and multivariable Cox regression analysis comparing no surgery with no neoadjuvant therapy plus surgery for the OS of AJCC 8th T4N0-3M0 EC patients. Supplementary Table S6. Univariable and multivariable Cox regression analysis comparing neoadjuvant therapy plus surgery with no neoadjuvant therapy plus surgery for the OS of AJCC 8th T4N0-3M0 EC patients. Supplementary Table S7. Univariable and multivariable Cox regression analysis comparing no surgery with surgery for the OS of AJCC 8th IIIB-IVA esophageal adenocarcinoma patients. Supplementary Table S8. Univariable and multivariable Cox regression analysis comparing no surgery with surgery for the OS of AJCC 8th IIIB-IVA esophageal squamous cell carcinoma patients. Supplementary Figure S1. Baseline standardized mean difference before and after PSM for surgery vs. no surgery in T4N0-3M0 EC (A), surgery vs. no surgery in T4aN0-3M0 EC (B), surgery vs. no surgery in T4bN0-3M0 EC (C), Neo + surgery vs. no surgery in T4N0-3M0 EC (D), surgery without Neo vs. no surgery in T4N0-3M0 EC (E), and Neo + surgery vs. surgery without Neo in T4N0-3M0 EC (F). PSM, propensity score matching; EC, esophageal cancer; Neo, neoadjuvant therapy. Supplementary Figure S2. Subgroup analysis of HR for surgery vs. no surgery in OS of stage T4aN0-3M0 EC. HR, hazard ratio; OS, overall survival; EC, esophageal cancer; CI, confidential interval. Supplementary Figure S3. Subgroup analysis of HR for surgery vs. no surgery in OS of stage T4bN0-3M0 EC. HR, hazard ratio; OS, overall survival; EC, esophageal cancer; CI, confidential interval. Supplementary Figure S4. Baseline standardized mean difference before and after PSM for surgery vs. no surgery in IIIB-IVA esophageal adenocarcinoma patients (A), and IIIB-IVA esophageal squamous cell carcinoma patients (B). PSM, propensity score matching. Supplementary Figure S5. Survival curves of OS for stage IIIB-IVA esophageal adenocarcinoma comparing surgery with no surgery before PSM (A) and after PSM (B), IIIB-IVA esophageal squamous cell carcinoma comparing surgery with no surgery before PSM (C) and after PSM (D). OS, overall survival; PSM, propensity score matching.