cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Indoor residual spraying for malaria control in sub-Saharan Africa 1997 to 2017: an adjusted retrospective analysis
Creators: name: Julie-Anne A. Tangena
name: Hendriks, Chantal M. J.
name: Devine, Maria
name: Tammaro, Meghan
name: Trett, Anna E.
name: Williams, Ignatius
name: Adilson José DePina
name: Achamylesh Sisay
name: Ramandimbiarijaona Herizo
name: Hmooda Toto Kafy
name: Chizema, Elizabeth
name: Were, Allan
name: Rozier, Jennifer
name: Coleman, Michael
name: Moyes, Catherine L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Maps showing modelled insecticide-treated bed net (ITN) coverage from Bhatt and Gething [35].
Additional file 3 of Indoor residual spraying for malaria control in sub-Saharan Africa 1997 to 2017: an adjusted retrospective analysis
Creators: name: Julie-Anne A. Tangena
name: Hendriks, Chantal M. J.
name: Devine, Maria
name: Tammaro, Meghan
name: Trett, Anna E.
name: Williams, Ignatius
name: Adilson José DePina
name: Achamylesh Sisay
name: Ramandimbiarijaona Herizo
name: Hmooda Toto Kafy
name: Chizema, Elizabeth
name: Were, Allan
name: Rozier, Jennifer
name: Coleman, Michael
name: Moyes, Catherine L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3:Plasmodium falciparum infection prevalence from Bhatt et al. [1].
Efficient Beamforming Feedback Information-Based Wi-Fi Sensing by Feature Selection
Creators: name: Li, Xin
name: Hu, Jingzhi
name: Luo, Jun
Publisher: name: arXiv
Year: 2024
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Wi-Fi sensing leveraging plain-text beamforming feedback information (BFI) in multiple-input-multiple-output (MIMO) systems attracts increasing attention. However, due to the implicit relationship between BFI and the channel state information (CSI), quantifying the sensing capability of BFI poses a challenge in building efficient BFI-based sensing algorithms. In this letter, we first derive a mathematical model of BFI, characterizing its relationship with CSI explicitly, and then develop a closed-form expression of BFI for 2x2 MIMO systems. To enhance the efficiency of BFI-based sensing by selecting only the most informative features, we quantify the sensing capacity of BFI using the Cramer-Rao bound (CRB) and then propose an efficient CRB-based BFI feature selection algorithm. Simulation results verify that BFI and CSI exhibit comparable sensing capabilities and that the proposed algorithm halves the number of features, reducing 20% more parameters than baseline methods, at the cost of only slightly increasing positioning errors.
PROYECTO DISEÑO, IMPLEMENTACIÓN Y EVALUACIÓN DE PROGRAMAS Y PROYECTOS DE ETP
Creators: name: Cosme, María Cristina
Publisher: name: Zenodo
Year: 2020
Subjects: Proyecto- ABP- REALIDAD AUMENTADA

description: Este proyecto pertenece a un modulo de cursado de un Postitulo denominado Gestión de EDUCACIÓN TÉCNICO PROFESIONAL, la misma estaba organizada por ENFOCO En formación Continua Educación Técnico Profesional perteneciente al INET Instituto Nacional de Educación Tecnológica Ministerio de Educación de la Nación Argentina.
Ferramenta da Terapia Psicodinâmica: Identificação e Análise de Comportamentos de Projeção
Creators: name: Brandl, Edenilson
Publisher: name: Zenodo
Year: 2024
Subjects: Ferramenta da Terapia Psicodinâmica
Identificação e Análise de Comportamentos de Projeção
Terapia Psicodinâmica
Enciclopédia da Conscienciologia

description: Definologia: A Ferramenta da Terapia Psicodinâmica voltada para a identificação e análise de comportamentos de projeção é uma técnica terapêutica utilizada no âmbito da psicologia clínica para investigar e compreender os processos psíquicos que envolvem a projeção de conteúdos internos do indivíduo em outras pessoas ou situações externas.
Dry Eye-Related Visual Blurring and Irritative Symptoms and Their Association with Depression and Anxiety in Eye Clinic Patients
Creators: name: Liyue, Hong
name: Chiang, Peggy Pei-Chia
name: Sung, Sharon C.
name: Tong, Louis
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Purpose: Dry eye is a common condition known to have many systemic co-morbidities. We aim to report the frequency of depression and anxiety suspects in eye clinic patients and explore the association between dry eye signs and symptoms with depression and anxiety. Materials and methods: Adult outpatients were recruited from dry a public tertiary ophthalmology specialist center. Participants underwent socio-demographic and dry eye symptoms questionnaires, fluorescein dye tear break-up time (TBUT), fluorescein dye corneal staining and Schirmer’s test. Rasch analysis was used to internally validate the Hospital Anxiety and Depression Scale (HADS) and the Center for Epidemiologic Studies Depression Scale (CES-D) and determine its psychometric properties. Results: A total of 96 participants (mean age 54.5 ± 10.8; 64.1% women) were recruited. The mean score for the CES-D was 12.1 ± 9.8 with 28 participants (31.5%) having a score of above 16 (published threshold). The mean score for depression-associated questions in the HADS was 3.6 ± 3.6 with 13 participants (14.1%) having a score ≥8. The mean score for the anxiety-associated questions in the HADS was 5.3 ± 3.6 with 24 participants (26.1%) having score ≥8. There was a weak inverse correlation between Schirmer’s test and CES-D scores. Elevated depression scores from the CES-D were significantly associated with visual blurring but not irritation, in dry eye patients with low TBUT. Conclusions: In conclusion, specific types of dry eye symptoms, particularly those with increased frequency of visual blurring were associated with symptoms of depression. The optical aberrations induced by dry eye, associated with tear instability, may predispose to depressive tendency.
Methylphenidate and environmental enrichment ameliorate the deleterious effects of prenatal stress on attention functioning
Creators: name: Zubedat, Salman
name: Aga-Mizrachi, Shlomit
name: Avital, Avi
name: Cymerblit-Sabba, Adi
name: Ritter, Ami
name: Nachmani, Maayan
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Astronomy, Astrophysics, Space Science
subject: Pharmacology
subject: Neuroscience

description: Either pre- or post-natal environmental factors seem to play a key role in brain and behavioral development and to exert long-term effects. Increasing evidence suggests that exposure to prenatal stress (PS) leads to motor and learning deficits and elevated anxiety, while enriched environment (EE) shows protective effects. The dopaminergic system is also sensitive to environmental life circumstances and affects attention functioning, which serves as the preliminary gate to cognitive processes. However, the effects of methylphenidate (MPH) on the dopaminergic system and attentional functioning, in the context of these life experiences, remain unclear. Therefore, we aimed to examine the effects of EE or PS on distinct types of attention, along with possible effects of MPH exposure. We found that PS impaired selective attention as well as partial sustained attention, while EE had beneficial effects. Both EE and MPH ameliorated the deleterious effects of PS on attention functioning. Considering the possible psychostimulant effect of MPH, we examined both anxiety-like behavior as well as motor learning. We found that PS had a clear anxiogenic effect, whereas EE had an anxiolytic effect. Nevertheless, the treatment with both MPH and/or EE recovered the deleterious effects of PS. In the motor-learning task, the PS group showed superior performance while MPH led to impaired motor learning. Performance decrements were prevented in both the PS + MPH and EE + MPH groups. This study provides evidence that peripubertal exposure to EE (by providing enhanced sensory, motor, and social opportunities) or MPH treatments might be an optional therapeutic intervention in preventing the PS long-term adverse consequences.
Insulin involved Akt/ERK and Bcl-2/Bax pathways against oxidative damages in C6 glial cells
Creators: name: Ramalingam, Mahesh
name: Kim, Sung-Jin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Insulin, a hypoglycemic hormone, has multiple functions in the brain. The aim of this study to identify the mechanisms of insulin in hydrogen peroxide (H2O2)-induced toxicity in the C6 glial cells. Cytotoxicity, lactate dehydrogenase, nitric oxide, reactive oxygen species and calcium ion, lipid peroxidation, protein oxidation and glutathione levels were determined. Signaling pathway molecules were assessed by western blotting and RT-PCR. The results showed that treatment with insulin reduced the cell death and cell membrane damages against H2O2-induced toxicity. Furthermore, insulin interfered H2O2-induced intracellular generation of reactive oxygen species and calcium-ion transport, apoptosis, including lipid and protein oxidation products. Cells treated with insulin reverted H2O2-induced suppression of reduced glutathione levels by blocking oxidized glutathione. Moreover, insulin treatment activates Akt, restores ERK1/2 and Bcl-2 by preventing Bax and Bax/Bcl-2 ratio. Our results suggest that treatment of insulin exerts potential role against 24 h of H2O2-induced toxicity in C6 cells.
title: Дистанционное образование в условиях цифровой трансформации современного вуза
Creators: name: ELS IPR BOOKS
Publisher: name: Вузовское образование
Year: 2024

description: В монографии рассматриваются вопросы цифровой трансформации современного образования и роль дистанционного формата в реализации стратегий современного вуза. В процессе исследования авторы теоретически обосновали понятия цифровой трансформации, выявили основные векторы ее направления в образовательных организациях. Кроме того, детально проанализировано понятие дистанционного образования, исторические аспекты его развития, основные виды и функции. Авторами отдельно подчеркивается роль электронно-библиотечных систем, как важного источника лицензионного учебно-методического контента, их основные характеристики и специфика применения в дистанционном образовании. На основе эмпирического исследования сделаны выводы о преимуществах и недостатках дистанционного образования, а также предложены практические рекомендации по его дальнейшему развитию. Монография может быть использована преподавателями и студентами всех направлений подготовки с акцентом на укрупненную группу «Образование и педагогические науки», а также руководителями профильных отделов образовательных организаций для выработки стратегии дистанционного образования.
STROBE-checklist-v4-combined.doc
Creators: name: palimar, vikram
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 429999
subject: Other health sciences not elsewhere classified

description: Background: Sudden and unexpected deaths are increasing drastically. The main cause of sudden death is cardiovascular disease, out of which coronary artery disease predominates forming 80% of the cases. Most of the time, detecting early changes in myocardial infarction during the autopsy is challenging since gross infarct changes do not appear until after 24 to 48 hours of myocardial ischemia injury. So, the aim of this study was to compare two test to detect early changes of Myocardial Infarction one by using Triphenyl Tetrazolium Chloride (TTC) staining of the myocardial tissue, during autopsy and other by histopathological examination.Methods: The sample size of 60 hearts taken from all the sudden deaths cases brought to Mortuary with suspected cause of death due to cardiac origin. The heart was obtained from the deceased by standard post-mortem technique. Serial full-thickness transverse sections of the heart were taken at 2 cm intervals from the apex to the atrioventricular groove. All the serial slices of heart is taken for histochemical staining and TTC staining.Results: In histopathological examination 34 hearts were diagnosed with myocardial infarction and 26 hearts reported non myocardial infarction. With TTC 40 hearts remained unstained suggestive of myocardial infarction and 30 hearts were stained suggestive of non-infarcted hearts. TTC staining in our study shows an accuracy of 88.33%.Conclusion: The result of this study shows that the Triphenyl Tetrazolium Chloride test, a histochemical staining technique of heart, is reliable approach for forensic pathologists to diagnose early myocardial infarction during the post-mortem examination.
Identifying the attended speaker using electrocorticographic (ECoG) signals
Creators: name: K.V. Dijkstra
name: P. Brunner
name: A. Gunduz
name: W. Coon
name: A.L. Ritaccio
name: J. Farquhar
name: G. Schalk
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Neuroscience
subject: Engineering

description: People affected by severe neuro-degenerative diseases (e.g., late-stage amyotrophic lateral sclerosis (ALS) or locked-in syndrome) eventually lose all muscular control. Thus, they cannot use traditional assistive communication devices that depend on muscle control, or brain-computer interfaces (BCIs) that depend on the ability to control gaze. While auditory and tactile BCIs can provide communication to such individuals, their use typically entails an artificial mapping between the stimulus and the communication intent. This makes these BCIs diffcult to learn and use. In this study, we investigated the use of selective auditory attention to natural speech as an avenue for BCI communication. In this approach, the user communicates by directing his/her attention to one of two simultaneously presented speakers. We used electrocorticographic (ECoG) signals in the gamma band (70–170 Hz) to infer the identity of the attended speaker, thereby removing the need to learn such an artificial mapping. Our results from 12 human subjects show that a single cortical location over superior temporal gyrus or premotor cortex is typically sufficient to identify the attended speaker within 10 s and with 77% accuracy (50% accuracy due to chance). These results lay the groundwork for future studies that may determine the real-time performance of BCIs based on selective auditory attention to speech.
Magnesiation of N-Heterocycles Using i-PrMgCl · LiCl and Catalytic Diisopropylamine
Creators: name: W. Nxumalo
name: A. Dinsmore
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Biochemistry
Biophysics

description: The direct magnesiation of various N-heterocyclic compounds with i-PrMgCl · LiCl and catalytic diisopropylamine allows for preparation of 2-substituted pyrroles, imidazole, indoles, and benzimidazoles, in moderate to good yields. The magnesiated substrates canreadily undergo a Kumada-type coupling with iodo-aryls in the presence of catalytic Pd(PPh3)4.
Insulin involved Akt/ERK and Bcl-2/Bax pathways against oxidative damages in C6 glial cells
Creators: name: Ramalingam, Mahesh
name: Kim, Sung-Jin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Insulin, a hypoglycemic hormone, has multiple functions in the brain. The aim of this study to identify the mechanisms of insulin in hydrogen peroxide (H2O2)-induced toxicity in the C6 glial cells. Cytotoxicity, lactate dehydrogenase, nitric oxide, reactive oxygen species and calcium ion, lipid peroxidation, protein oxidation and glutathione levels were determined. Signaling pathway molecules were assessed by western blotting and RT-PCR. The results showed that treatment with insulin reduced the cell death and cell membrane damages against H2O2-induced toxicity. Furthermore, insulin interfered H2O2-induced intracellular generation of reactive oxygen species and calcium-ion transport, apoptosis, including lipid and protein oxidation products. Cells treated with insulin reverted H2O2-induced suppression of reduced glutathione levels by blocking oxidized glutathione. Moreover, insulin treatment activates Akt, restores ERK1/2 and Bcl-2 by preventing Bax and Bax/Bcl-2 ratio. Our results suggest that treatment of insulin exerts potential role against 24 h of H2O2-induced toxicity in C6 cells.
Insulin involved Akt/ERK and Bcl-2/Bax pathways against oxidative damages in C6 glial cells
Creators: name: Ramalingam, Mahesh
name: Kim, Sung-Jin
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Biochemistry

description: Insulin, a hypoglycemic hormone, has multiple functions in the brain. The aim of this study to identify the mechanisms of insulin in hydrogen peroxide (H2O2)-induced toxicity in the C6 glial cells. Cytotoxicity, lactate dehydrogenase, nitric oxide, reactive oxygen species and calcium ion, lipid peroxidation, protein oxidation and glutathione levels were determined. Signaling pathway molecules were assessed by western blotting and RT-PCR. The results showed that treatment with insulin reduced the cell death and cell membrane damages against H2O2-induced toxicity. Furthermore, insulin interfered H2O2-induced intracellular generation of reactive oxygen species and calcium-ion transport, apoptosis, including lipid and protein oxidation products. Cells treated with insulin reverted H2O2-induced suppression of reduced glutathione levels by blocking oxidized glutathione. Moreover, insulin treatment activates Akt, restores ERK1/2 and Bcl-2 by preventing Bax and Bax/Bcl-2 ratio. Our results suggest that treatment of insulin exerts potential role against 24 h of H2O2-induced toxicity in C6 cells.
Towards cross-country comparable reference budgets in Europe: a methodological note on the development of food baskets, EuSocialCit
Creators: name: Carrillo Álvarez, Elena
name: Muñoz-Martinez, Júlia
name: Cornelis, Ilse
name: frederickx, Marieke
name: Cussó Parcerisas, Irene
name: Penne, Tess
name: Delanghe, Heleen
name: Storms, Bérénice
Publisher: name: Zenodo
Year: 2024

description: In the context of the current EuSocialCit project, additional steps have been taken towards elaborating a methodology to calculate and price cross-nationally comparable food baskets representing a healthy and sustainable diet. The methodology has been   implemented in four European countries (Belgium, Finland, Hungary and Spain). In this methodological note, we outline the methodological choices and considerations and the necessary steps for the future development of comparable RBs across Europe.
Urease inhibitory profile of extracts and chemical constituents of Pistacia atlantica ssp. cabulica Stocks
Creators: name: Ghias Uddin
name: , Ismail
name: Abdur Rauf
name: Muslim Raza
name: Khan, Haroon
name: Nasruddin
name: Khan, Majid
name: Farooq, Umar
name: Khan, Ajmal
name: Arifullah
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Hematology

description: The current study was designed to evaluate the urease inhibitory profile of extract and fractions of Pistacia atlantica ssp. cabulica Stocks followed by bioactivity-guided isolated compounds. The crude extract was found significantly active with urease inhibitor (95.40% at 0.2 mg/mL) with IC50 values of 32.0 ± 0.28 μg/mL. Upon fractionation, ethyl acetate fraction displayed 100% urease inhibition with IC50 values of 19.9 ± 0.51 μg/mL at 0.2 mg/mL. However, n-hexane and chloroform fractions exhibited insignificant urease inhibition. Similarly, the isolated compound, transilitin (1) and dihydro luteolin (2) demonstrated marked urease attenuation with 95 and 98% respectively, at 0.15 mg/mL. Both the isolated compounds showed marked potency with IC50 values of 8.54 ± 0.54 and 9.58 ± 2.22 μg/mL, respectively. In short, both the extract and fractions and isolated compounds showed marked urease inhibition and thus a useful natural source of urease inhibition. Graphical abstract showing the image Pistacia atlantica, chemical structure of isolated compounds and urease enzyme.
Diaryltriazolium Photoswitch: Reaching a Millisecond Cycloreversion with High Stability and NIR Absorption
Creators: name: Kolarski, Dušan
name: Steinbach, Pit
name: Bannwarth, Christoph
name: Klaue, Kristin
name: Hecht, Stefan
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Click Chemistry
subject: Diarylethenes
subject: Diaryltriazolium
subject: Photochromism
subject: Photoswitches
subject: 540 Chemie und zugeordnete Wissenschaften

description: The exceptional thermal stability of diarylethene closed isomers enabled many applications but also prevented utilization in photochromic systems that require rapid thermal reversibility. Herein, we report the diaryltriazolium (DAT+) photoswitch undergoing thermal cycloreversion within a few milliseconds and absorption of the closed form in the near-infrared region above 900 nm. Click chemistry followed by alkylation offers modular and fast access to the electron-deficient DAT+ scaffold. In addition to excellent fatigue resistance, the introduced charge increases water solubility, rendering this photoswitch an ideal candidate for exploring biological applications.
Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthma
Creators: name: Kashon, Michael L.
name: Johnson, Victor J.
name: Louis-Philippe Boulet
name: Luster, Michael I.
name: Bernstein, David I.
name: Berran Yucesoy
name: Lummus, Zana L.
name: Fluharty, Kara
name: Gautrin, Denyse
name: Cartier, André
name: Joaquin Sastre
name: Quirce, Santiago
name: Tarlo, Susan M.
name: Maria-Jesus Cruz
name: Munoz, Xavier
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Genetics

description: Diisocyanates are the most common cause of occupational asthma, but risk factors are not well defined. A case-control study was conducted to investigate whether genetic variants in inflammatory response genes (TNFα, IL1α, IL1β, IL1RN, IL10, TGFB1, ADAM33, ALOX-5, PTGS1, PTGS2 and NAG-1/GDF15) are associated with increased susceptibility to diisocyanate asthma (DA). These genes were selected based on their role in asthmatic inflammatory processes and previously reported associations with asthma phenotypes. The main study population consisted of 237 Caucasian French Canadians from among a larger sample of 280 diisocyanate-exposed workers in two groups: workers with specific inhalation challenge (SIC) confirmed DA (DA+, n = 95) and asymptomatic exposed workers (AW, n = 142). Genotyping was performed on genomic DNA, using a 5′ nuclease PCR assay. After adjusting for potentially confounding variables of age, smoking status and duration of exposure, the PTGS1 rs5788 and TGFB1 rs1800469 single nucleotide polymorphisms (SNP) showed a protective effect under a dominant model (OR = 0.38; 95% CI = 0.17, 0.89 and OR = 0.38; 95% CI = 0.18, 0.74, respectively) while the TNFα rs1800629 SNP was associated with an increased risk of DA (OR = 2.08; 95% CI = 1.03, 4.17). Additionally, the PTGS2 rs20417 variant showed an association with increased risk of DA in a recessive genetic model (OR = 6.40; 95% CI = 1.06, 38.75). These results suggest that genetic variations in TNFα, TGFB1, PTGS1 and PTGS2 genes contribute to DA susceptibility.
XR4HUMAN D4.1: Map existing and emerging requirements for interoperability in XR and Spatial Computing
Creators: name: Kadlubsky, Alina
name: Kumar Renganayagalu, Sathiya
name: Salazar, Mikel
Publisher: name: Zenodo
Year: 2023

description: ABSTRACT

This report aims to provide the current state of interoperability in the eXtended Reality (XR) and spatial computing field and assesses its emerging requirements. We employed Systematic Literature Review (SLR) method to examine and map the current state of interoperability standards, frameworks, guidelines, and identify the limitations to elicit future requirements.
Essential oil composition and biological activity from Artemisia caerulescens subsp. densiflora (Viv.) Gamisans ex Kerguélen & Lambinon (Asteraceae), an endemic species in the habitat of La Maddalena Archipelago
Creators: name: Ornano, Luigi
name: Venditti, Alessandro
name: Ballero, Mauro
name: Sanna, Cinzia
name: Donno, Yuri
name: Quassinti, Luana
name: Bramucci, Massimo
name: Vitali, Luca A.
name: Dezemona Petrelli
name: Tirillini, Bruno
name: Papa, Fabrizio
name: Maggi, Filippo
name: Armanodoriano Bianco
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: The purpose of this study was to investigate the composition of the essential oil obtained from a population of Artemisia caerulescens subsp. densiflora growing in Razzoli, an island in the La Maddalena Archipelago (Sardinia, Italy). A. caerulescens sups. densiflora Viv. (Asteraceae), a wild herb, seldom studied in the Mediterranean, represents one of the many rare endemic species growing in North Sardinia. The essential oil composition was analysed by means of GC/MS analysis, which showed davana ethers as the major volatile components, accounting together for 17.5%, followed by (E)-nerolidol (4.5%), β-oplopenone (3.3%), cis-sabinene hydrate (5.2%) and terpinen-4-ol (4.7%). The oil was tested for antioxidant activity by means of DPPH test, inhibition of lipid oxidation test and hypochlorous acid test, which showed a quite interesting scavenger capacity. For the first time, we reported the cytotoxic activity of the essential oil of A. caerulescens subsp. densiflora, against three human tumour cell lines (A375, MDA-MB231 and HCT116), with IC50 values in the range 5.20–7.61 μg/mL, which deserved further studies to support its use as chemopreventive agent. Finally, the antimicrobial activity of the essential oil, displayed on a panel of human pathogens, was very low. Artemisia caerulescens subsp. densiflora (Viv.) Gamisans ex Kerguélen & Lambinon (Asteraceae)
Teachers’ experience and training with visual diagrams production
Creators: name: Fernández, Beatriz García
name: Ruiz-Gallardo, José-Reyes
name: Paños, Esther
name: Jiménez, Antonio Mateos
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Neuroscience
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Science Policy
Mental Health

description: This study aims to explore the experience and training of pre-service and in-service teachers (n = 470) using visual diagrams. For this purpose, they answered a questionnaire regarding their training and experience with them throughout their entire education. The results show that teachers’ experience with visual diagrams was very limited at all educational stages and subjects. They consider them valuable for learning, but they have received little instruction on diagrams, copying existing materials rather than producing original ones. They mainly produced their own visual diagrams in Natural and Social Sciences. They also produced other type of diagrams (mainly quantitative and verbal) in non-STEM subjects. The results indicate a need to provide teachers with training and opportunities to practice with visual diagrams, and to make them competent to use them in their teaching to increase their didactic use with their students throughout the educational system.
Magnesiation of N-Heterocycles Using i-PrMgCl.LiCl and Catalytic Diisopropylamine
Creators: name: W. Nxumalo
name: A. Dinsmore
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Biochemistry
Biophysics

description: The direct magnesiation of various N-heterocyclic compounds with i-PrMgCl.LiCl and catalytic diisopropylamine allows for preparation of 2-substituted pyrroles, imidazole, indoles and benzimidazoles, in moderate to good yields. The magnesiated substrates can readily undergo a Kumada-type coupling with iodo-aryls in the presence of catalytic Pd(PPh3)4.
Synthesis and biological activity of ester derivatives of mycophenolic acid and acridines/acridones as potential immunosuppressive agents
Creators: name: Cholewinski, Grzegorz
name: Iwaszkiewicz-Grzes, Dorota
name: Trzonkowski, Piotr
name: Dzierzbicka, Krystyna
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Improved derivatives of mycophenolic acid (MPA) are necessary to reduce the frequency of adverse effects, this drug exerts in treated patients. In this study, MPA was coupled with N-(ω-hydroxyalkyl)-9-acridone-4-carboxamides or N-(ω-hydroxyalkyl)acridine-4-carboxamides to give respective ester conjugates upon Yamaguchi protocol. This esterification required protection of phenol group in MPA. Designed conjugates revealed higher potency in vitro than parent MPA. Acridine derivatives were more active than acridone analogs and length of the alkyl linker between MPA and heterocyclic units influenced the observed cytotoxicity. Derivatives 2b, 2d, 3a, 3b displayed the most promising immunosuppressive activity.
Maintaining plausible calorie intakes, crop yields and crop land expansion in long-run simulations with Computable General Equilibrium Models
Creators: name: Britz, Wolfgang
name: Britz, Wolfgang
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Food Security and Poverty
subject: long run baselines
subject: food demand
subject: calories
subject: Computable General Equilibrium analysis

description: We demonstrate how a combination of different elements can jointly provide plausible long-term trends for calorie intakes, crop yields and land use in Computable General Equilibrium (CGE) analysis. Specifically, we depict household demand based on a MAIDADS demand system estimated based on cross-sectional data. In order to control for calorie intake we first regress calorie intake on per capita income and construct a Leontief inverse to derive implicit calorie intakes from the final consumption of processed food. This allows jointly shifting preferences of the MAIDADS system by updating commitment terms and marginal budget shares, to arrive at plausible per capita calorie intakes during baseline construction. We control yields based on exogenous projections which we also use to parameterize our land supply functions. The contribution of the different elements is evaluated by comprising key developments in baselines up to 2050 constructed with different model variants
Antimycoplasmic activity and seasonal variation of essential oil of Eugenia hiemalis Cambess. (Myrtaceae)
Creators: name: Zatelli, Gabriele Andressa
name: Zimath, Priscila
name: Adrielli Tenfen
name: Cordova, Caio Maurício Mendes De
name: Dilamara Riva Scharf
name: Edésio Luiz Simionatto
name: Alberton, Michele Debiasi
name: Falkenberg, Miriam
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: The purpose of this work was to study the chemical composition and antimycoplasmic and anticholinesterase activities of the essential oil of Eugenia hiemalis leaves collected throughout the year. A total of 42 compounds were identified by CG, and are present in almost every seasons. Sesquiterpenes were dominant (86.01–91.48%), and non-functionalised sesquiterpenes comprised the major fraction, which increased in the summer; monoterpenes were not identified. The major components were spathulenol (5.36–16.06%), δ-cadinene (7.50–15.93%), bicyclogermacrene (5.70–14.24%) and β-caryophyllene (4.80–9.43%). The highest oil yield was obtained in summer and autumn. Essential oils presented activity against three evaluated Mycoplasma strains, but no activity was observed in the anticholinesterase assay.
Use of video modelling to teach complex and meaningful job skills to an adult with autism spectrum disorder
Creators: name: Rausa, Vanessa C.
name: Moore, Dennis W.
name: Anderson, Angelika
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective: To examine the effectiveness of a video modelling (VM) intervention to teach job-related telephone skills to an adult with Autism Spectrum Disorder (ASD). Methods: A multiple baseline design across four telephone-relevant behaviours was used to assess the effects of the intervention on the participant’s ability to respond to telephone calls. Results: Use of the VM intervention led to immediate improvements in listening and responding to both orders and complaints; more gradual improvements were also observed in the participant’s professional speech. All skill increases were maintained at follow-up. Conclusion: VM may be an effective method of teaching complex vocational skills to adults with ASD, although a stronger focus on social skills may be warranted in the future.
MRL/MpJ-Faslpr mice show abnormalities in ovarian function and morphology with the progression of autoimmune disease
Creators: name: Ichii, Osamu
name: Otsuka-Kanazawa, Saori
name: Chihara, Masataka
name: Nakamura, Teppei
name: Kon, Yasuhiro
name: Otani, Yuki
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Developmental Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Astronomy, Astrophysics, Space Science
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Physiology
subject: Neuroscience
subject: Medicine
subject: Biochemistry

description: The immune system is known to affect reproductive function, and maternal–fetal immune tolerance is essential for a successful pregnancy. To investigate the relationship between autoimmune disease and female reproductive function, we performed a comparative analysis of the ovarian phenotypes for C57BL/6 mice, autoimmune disease-prone MRL/MpJ (MRL/+) mice and congenic MRL/MpJ-Faslpr (MRL/lpr) mice harboring a mutation in the Fas gene that speeds disease onset. Both MRL-background strains showed earlier vaginal opening than C57BL/6 mice. The estrous cycle became irregular by 6 and 12 months of age in MRL/lpr mice and mice of the other two strains, respectively. Histological analysis at 3 months revealed that the number of primordial follicles was smaller in MRL-background mice than in C57BL/6 mice after 3 months. In addition, MRL/lpr and MRL/+ mice displayed lower numbers of ovarian follicles and corpora lutea at 3 and 6 months, and 6 and 12 months, respectively, than that in age-matched C57BL/6 mice. MRL/lpr and MRL/+ mice developed ovarian interstitial glands after 3 and 6 months, respectively. In particular, MRL/lpr mice showed numerous infiltrating lymphocytes within the ovarian interstitia, and partially stratified ovarian surface epithelia with more developed microvilli than that observed in C57BL/6 mice at 6 months. No significant differences in serum hormone levels were observed between the strains. In conclusion, MRL/lpr mice display altered ovarian development, morphology and function consistent with the progression of severe autoimmune disease, as these findings are less severe in MRL/+ counterparts.
Ferramenta da Terapia Humanista: Técnicas de Relaxamento Muscular Progressivo
Creators: name: Brandl, Edenilson
Publisher: name: Zenodo
Year: 2024
Subjects: Ferramenta da Terapia Humanista
Terapia Humanista
Técnicas de Relaxamento Muscular Progressivo
Enciclopédia da Conscienciologia

description: Definologia: As Técnicas de Relaxamento Muscular Progressivo (RMP) constituem uma ferramenta terapêutica utilizada no contexto da abordagem humanista da psicologia, com o objetivo de promover o alívio do estresse, da ansiedade e da tensão muscular por meio de uma sequência sistemática de relaxamento progressivo dos grupos musculares.
Acinetidae Stein 1859
Creators: name: Neuhaus, Birger
name: Lu, Borong
name: Yamasaki, Hiroshi
name: González-Casarrubios, Alberto
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Chromista
Ciliophora
Kinetofragminophora
Suctorida
Acinetidae

description: Species of Acinetidae at Sylt, North Sea.
Küsters (1974) reported four species of Acinetidae collected at Königshafen in the northern part of Sylt in 1969 and 1970 from experimentally exposed artificial substrates, viz, Acineta compressa Claparède & Lachmann, 1858, A. foetida Maupas, 1881, A. tuberosa (Ehrenberg, 1834), and Loricophrya tuba. These species mentioned by Küsters (1974) did not occur on our kinorhynch specimens of Setaphyes kielensis collected at Königshafen in 1998 or on S. dentatus and S. kielensis collected at Kampen in 1988 and 2016, but a different species, viz, Trematosoma husselae sp. nov. was found 1998 and 2016 at Kampen but not at Königshafen at any time (Tables 1–4; Küsters 1974). A suctorian species on the same basibionts and from the same location as in this study was briefly reported before by Neuhaus (2013, p. 331: “ Suctoria, possibly Acineta sp., are also common ectocommensals on Pycnophyes dentatus and P. kielensis from intertidal mudflats in northern Germany; few to several specimens attach to any free area on the trunk cuticle (Fig. 5.8.1D, E; Neuhaus own obs.)”). It turned out that the identification of the epibiont at that time was erroneous, and we here assign the species to Trematosoma husselae sp. nov.
description: Published as part of Neuhaus, Birger, Lu, Borong, Yamasaki, Hiroshi & González-Casarrubios, Alberto, 2023, Epibiontic life on intertidal Setaphyes kielensis and S. dentatus (Kinorhyncha, Pycnophyidae) from Sylt, North Sea, Germany, with a description of a new species of Trematosoma (Ciliophora, Acinetidae) and a redescription of Cothurnia buetschlii (Ciliophora, Vaginicolidae), pp. 439-470 in Zootaxa 5343 (5) on page 464, DOI: 10.11646/zootaxa.5343.5.2, http://zenodo.org/record/8345479
Humic acid removal by electrocoagulation: characterization of aluminum species and humic acid
Creators: name: Palacios, Ronna Jane S.
name: Do-Gun Kim
name: Seok-Oh Ko
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Hematology
subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: In this study, the different aluminum (Al) species generated during electrocoagulation (EC), the humic acid (HA) removal, and the change in HA characteristics were evaluated. The results show that the distribution of monomeric Al species (Ala), medium polymer Al species (Alb), and colloidal or solid Al species (Alc) was dependent on initial pH and current density (CD). The higher the fraction of Alb and Alc, the faster the HA removal. The fraction of Alb and HA removal rates were higher at an initial pH of 4.5 than at 6.5. At a CD of 29 A m−2, the fraction of Alb and Alc was higher and HA removal was faster than at 5 A m−2. The results of UV/Vis spectroscopy, fluorescence spectroscopy, and size-exclusion chromatography show a decrease in aromaticity, degree of conjugation, and average molecular weight after EC treatment. The decreases were more pronounced at a high CD than at a low CD, indicating that Alb and Alc, especially Alc, contribute much to the preferential removal of highly condensed and high molecular weight structures of HA by adsorption and patch coagulation.
Higgs measurements from CMS
Creators: name: Trevisani, Nicolò
Publisher: name: Scuola Internazionale Superiore di Studi Avanzati (SISSA)
Year: 2024

description: Ten years after the discovery of the Higgs boson in 2012, the data collected by CMS during the LHC Run 2 allows measuring many of the properties of this particle. A review of the recent Higgs results from CMS is presented in this report. They include mass, width, and differential cross-section measurements, together with coupling and charge-parity measurements. Additionally, the latest measurements of di-Higgs production are shown. Finally, a few results showing an excess of data over the predictions are illustrated.
Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors
Creators: name: Ceruso, Mariangela
name: Scozzafava, Andrea
name: Supuran, Claudiu T.
name: Antel, Sabrina
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Pharmacology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry

description: New ureido benzenesulfonamides incorporating a GABA moiety as a linker between the ureido and the sulfonamide functionalities were synthesized and their inhibition potency determined against both the predominant cytosolic (hCA I and II) and the transmembrane tumor-associated (hCA IX and XII) isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1). The majority of these compounds were medium potency inhibitors of the cytosolic isoform hCA I and effective hCA II inhibitors, whereas they showed strong inhibition of the two transmembrane tumor-associated isoforms hCA IX and XII, with KIs in nanomolar range. Only one derivative had a good selectivity for inhibition of the tumor-associated hCA IX target isoform over the cytosolic and physiologically dominant off-target hCA I and II, being thus a potential tool to develop new anticancer agents.
Kinorhyncha
Creators: name: Neuhaus, Birger
name: Lu, Borong
name: Yamasaki, Hiroshi
name: González-Casarrubios, Alberto
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Kinorhyncha

description: Species of suctorian ciliates on different basibionts of Kinorhyncha.
Zelinka (1914) described inadvertently the epibiontic Loricophrya tuba on Kinorhyncha from the Gulf of Trieste, because he mentioned the species's name in connection with identifying morphological characters. A more substantial description, the species name of the basibiont of this epibiont, Pycnophyes communis, and the record of Flectacineta livadiana? followed in his monograph (Zelinka 1928). Adrianov and Higgins (1996, fig. 23) labelled two epibionts of Pycophyes parasanjuanensis as “ectocommensal suctorians”, but these specimens represented a species of Cothurnia and not a suctorian. Dovgal et al. (2008) reported Limnoricus ponticus from an unidentified Indian species of Pycnophyes. Together with the new species reported in this article, four acinetid species are now known to settle on pycnophyid Kinorhyncha in European and Indian waters.
Trematosoma husselae sp. nov. was here reported from species of Kinorhyncha, but few other species of Trematosoma were known to settle on meiofauna, viz, T. amphiasci, T. bocqueti, and T. pusilla on Coepepoda, and T. rotunda on Nematoda (Precht 1935; Guilcher 1950; Allgén 1951; Fernandez-Leborans et al. 2012; Chatterjee et al. 2020, 2022).
description: Published as part of Neuhaus, Birger, Lu, Borong, Yamasaki, Hiroshi & González-Casarrubios, Alberto, 2023, Epibiontic life on intertidal Setaphyes kielensis and S. dentatus (Kinorhyncha, Pycnophyidae) from Sylt, North Sea, Germany, with a description of a new species of Trematosoma (Ciliophora, Acinetidae) and a redescription of Cothurnia buetschlii (Ciliophora, Vaginicolidae), pp. 439-470 in Zootaxa 5343 (5) on pages 464-465, DOI: 10.11646/zootaxa.5343.5.2, http://zenodo.org/record/8345479