cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Unmet needs in abnormal uterine bleeding due to ovulatory dysfunction
Creators: name: Simoncini, Tommaso
name: Arab, Hisham
name: Pedachenko, Nataliia
name: Tian, Qinjie
name: Pineda, Fernando
name: Puranam, Balamba
name: Sohail, Rubina
name: Wender, Maria Celeste Osorio
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Ovulatory disorders are a common cause of abnormal uterine bleeding in women of reproductive age. The International Federation of Gynecology and Obstetrics currently offers a causal classification system for ovulatory disorders but does not provide clear management recommendations. There remains regional disparity in treatment practices, often influenced by institutional and insurance regulations as well as cultural and religious practices. A panel of experts evaluated current gaps in ovulatory disorder management guidelines and discussed potential strategies for addressing these unmet needs. Key gaps included a lack in consensus about the effectiveness of combined estrogen and progestogen versus progestogen alone, a paucity of evidence regarding the relative effectiveness of distinct hormonal molecules, a lack of data regarding optimal treatment duration, and limited guidance on optimal sequencing of treatment. Recommendations included development of a sequential treatment-line approach and development of a clinical guide addressing treatment scenarios common to all countries, which can then be adapted to local practices. It was also agreed that current guidelines do not address the unique clinical challenges of certain patient groups. The panel discussed how the complexity and variety of patient groups made the development of one single disease management algorithm unlikely; however, a simplified, decision-point hierarchy could potentially help direct therapeutic choices. Overall, the panel highlighted that greater advocacy for a tailored approach to the treatment of ovulatory disorders, including wider consideration of non-estrogen therapies, could help to improve care for people living with abnormal uterine bleeding due to ovarian dysfunction.
Diagnostic value of ultrasound elastography in polycystic ovary syndrome: a systematic review and meta-analysis
Creators: name: Ruan, Zhongtan
name: Yu, Zhen
name: Qin, Qianyu
name: Tang, Ying
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: The main purpose of this systematic review and meta-analysis was to investigate the diagnostic value of ultrasound elastography in the evaluation of polycystic ovary syndrome (PCOS). A comprehensive and methodical investigation was carried out in the databases of PubMed, EMBASE, Cochrane, Scopus, Web of Science, and China National Knowledge Infrastructure, covering the entire duration of these databases until October 18, 2023. The primary purpose of this research was to evaluate and contrast ovarian tissue elasticity in people with and without PCOS. The elasticity of ovarian tissue was quantified using standardized mean difference (SMD). A total of eight studies were ultimately selected for systematic evaluation and meta-analysis. Five studies used shear wave elastography (SWE) as a diagnostic tool, and it was discovered that women with PCOS had higher levels of ovarian shear wave elasticity than their healthy counterparts. The SMD was determined to be 1.86 kilopascal (95% CI: 1.27 to 2.44). Three studies were conducted using strain elastography (SE) to compare the ovarian strain ratio of patients with PCOS to that of a healthy control group. The SMD for the PCOS group was 2.07 (95% CI: 1.79 to 2.34), which indicated that the ovarian strain ratio was significantly higher in that group. This systematic review and meta-analysis found that women with PCOS had stiffer ovarian tissue than women without the disorder. Ultrasound elastography may provide clinicians with value beyond 2D ultrasound in the diagnosis of PCOS.
Emergence of New Segments of Swiss Wine Consumers: A Comparison with a Segmentation Study from 2011
Creators: name: Brunner, Thomas
name: Schnetzer, Thomas
name: Delley, Mathilde
Publisher: name: Hindawi Publishing Corporation
Year: 2023

description: This study aimed to examine the various Swiss wine consumer segments, evaluate whether and how these segments had changed during the past decade, and formulate recommendations for targeted marketing. Data were collected through an online survey involving randomly selected Swiss households who were invited using flyers; the final sample size was N = 512. With the use of a shortened version of the questionnaire devised for a similar study published in 2011, we were able to compare the results of the said study with the present results. The results of the principal component analyses revealed eight factors. The factor scores were then used in hierarchical cluster analyses, which in turn revealed seven distinct segments of wine consumers. Four of these had already been identified 10 years ago: involved (21.9%), price-conscious (20.3%), lowbrow (16.0%), and image-oriented (5.3%) consumers. Three new segments emerged: local (15.2%), traditional (11.9%), and relaxation-seeking (9.4%) consumers. Our results show that each wine seller has its own place in the market and can benefit from the present study, which determines the appropriate marketing mix for a specific segment.
Exploring acetylation-related gene markers in polycystic ovary syndrome: insights into pathogenesis and diagnostic potential using machine learning
Creators: name: Wang, Jiqing
name: Wang, Yuqing
name: Li, Shanshan
name: Fang, Xiaoqin
name: Zhang, Chaoyue
name: Wang, Zuqing
name: Zheng, Yi
name: Deng, Hanzhi
name: Xu, Shifen
name: Mi, Yiqun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Plant Biology

description: Polycystic ovary syndrome (PCOS) is a prevalent cause of menstrual irregularities and infertility in women, impacting quality of life. Despite advancements, current understanding of PCOS pathogenesis and treatment remains limited. This study uses machine learning-based data mining to identify acetylation-related genetic markers associated with PCOS, aiming to enhance diagnostic precision and therapeutic efficacy. Advanced machine learning techniques were used to improve the precision of key gene identification and reveal their biological mechanisms. Validation on an independent dataset (GSE48301) confirmed their diagnostic value, assessed through ROC curves and nomograms for PCOS risk prediction. Molecular mechanisms of acetylation-related gene regulation in PCOS were further examined through clustering, immune-environmental, and gene network analyses. Our analysis identified 15 key acetylation-regulated genes differentially expressed in PCOS, including SGF29, NOL6, KLF15, and INO80D, which are relevant to PCOS pathogenesis. ROC curve analyses on training and validation datasets confirmed the model’s high diagnostic accuracy. Additionally, these genes were associated with immune cell infiltration, offering insights into the inflammatory aspect of PCOS. The identified acetylation gene markers offer novel insights into the molecular mechanisms underlying PCOS and hold promise for enhancing the development of precise diagnostic and therapeutic strategies.
A review of antioxidant N-acetylcysteine in addressing polycystic ovary syndrome
Creators: name: Yifu, Pu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: N-acetylcysteine (NAC), a compound known for its cysteine and glutathione precursor properties, has been used in therapeutic applications for many years. Recently, there has been increasing interest in exploring the potential benefits of NAC in addressing polycystic ovary syndrome (PCOS). However, the exact mechanisms underlying NAC’s therapeutic and clinical uses remain not fully understood. This review aims to specifically investigate how NAC offers protection against PCOS. This involved an extensive systematic review of the literature, and it made use of PubMed, Embase, and Web of Science databases. By analyzing key findings from over 100 research papers, the potential mechanisms through which NAC produces its effects were explored and summarized. Most studies suggest that NAC, whether used on its own or in combination with other medications, has the potential to counteract oxidative stress, utilize its anti-inflammatory and anti-apoptotic properties, and offer benefits in managing PCOS. Moreover, NAC might have the potential to influence specific signaling pathways in insulin target cells and β cells. Diverse biological effects of NAC indicate its potential usefulness as a supplementary or therapeutic approach for managing PCOS. As a result, additional research is required to explore its potential in addressing PCOS.
Launching for success: The effects of psychological distance and mental simulation on funding decisions and crowdfunding performance
Creators: name: Kaminski, Jermain
name: Rose, Stefan
name: Wentzel, Daniel
name: Hopp, Christian
Publisher: name: Elsevier
Year: 2020
Subjects: Crowdfunding New product development Entrepreneurial financing Construal level theory Psychological distance Mental simulation

description: This research examines how potential backers form mental representations of products in reward-based crowdfunding campaigns, and how these representations affect funding decisions and campaign performance. To test our framework, we conducted four experiments and also drew on a sample of 961 Kickstarter campaigns. Our results show that two campaign characteristics – the product's development stage and the indicated time to product delivery – determine the psychological distance that supporters experience in response to a campaign, and that psychological distance, in turn, inhibits individual campaign contributions and cumulative campaign success. Furthermore, we find that encouraging supporters to imagine the benefits of product usage is an effective means to increase support for campaigns that elicit high psychological distance.
Dienogest does not augment the gene expression of adhesion molecules, MCP-1, and monocyte adherence in human endothelial cells
Creators: name: Tahara, Nanami
name: Ito, Fumitake
name: Kawamata, Mari
name: Otani, Masahiro
name: Mori, Taisuke
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology
subject: Computational Biology

description: Medroxyprogesterone acetate (MPA) may increase the risk of atherosclerosis during hormone replacement therapy (HRT); therefore, the effect of progestogens other than MPA on atherosclerotic lesions requires evaluation. Adhesion of monocytes to vascular endothelial cells is an important early step in atherosclerosis progression. MCP-1 is a key chemokine that promotes monocyte migration and adhesion to vascular endothelial cells. In this study, we investigated the effects of dienogest (DNG), an alternative progestogen, on monocyte adhesion and cytokine expression in human umbilical vein endothelial cells (HUVECs). HUVECs were treated with DNG, natural progesterone, or MPA, followed by interleukin (IL)-1β stimulation. The mRNA expression of adhesion molecules (E-selectin and ICAM-1) and cytokines (MCP-1 and IL-6) was examined using real-time PCR. A flow chamber system was used to examine the effect of DNG on the adhesion of U937 monocytic cells to monolayer HUVECs. Unlike MPA, DNG did not alter the mRNA expression of E-selectin, ICAM-1, MCP-1, and IL-6 in HUVECs. Moreover, it did not increase the number of monocytes adhering to HUVECs in the flow chamber system. However, MPA treatment significantly enhanced monocyte adhesion to HUVECs (p < 0.05). DNG had no effect on the mRNA expression of adhesion molecules and cytokines in HUVECs, as well as the monocyte adhesion to HUVECs, suggesting that DNG can be explored as an alternative to MPA for HRT.
The in vitro mechanism of Vaspinregulates the proliferation and steroidogenesis of rat lutein cells
Creators: name: Fu, Xiao-wen
name: Liu, Ling
name: Zhu, Xiao-yu
name: Wang, Jian-jun
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Stable luteal cell function is an important prerequisite for reproductive ability and embryonic development. However, luteal insufficiency seriously harms couples who have the desire to have a pregnancy, and the most important thing is that there is no complete solution. In addition, Vaspin has been shown to have regulatory effects on luteal cells, but the complex mechanisms involved have not been fully elucidated. Therefore, this study aimed to explore the effect of Vaspin on rat luteal cells and its mechanism. Granulosa lutein cells separated from the ovary of female rats were incubated for 24h with gradient concentrations of Vaspin, and granulosa lutein cells incubated with 0.5% bovine serum albumin were used as controls. The proliferation, apoptosis, angiogenesis, progesterone (P4) and estradiol (E2) were detected by CCK-8, Anneixn-FITC/PI staining, angiogenesis experiment and ELISA. Western blot was applied to observe the expression levels of proteins related to cell proliferation, apoptosis, angiogenesis and MEK/MAPK signaling pathway. Compared with the Control group, Vaspin could significantly up-regulate the proliferation of granulosa lutein cells and reduce the apoptosis. Moreover, Vaspin promoted the angiogenesis of granulosa lutein cells and the production of P4 and E2 in a concentration-dependent manner. Furthermore, Vaspin up-regulated the CyclinD1, CyclinB1, Bcl2, VEGFA and FGF-2 expression in granulosa lutein cells, and down-regulated the level of Bax. Also, Vaspin increased the p-MEK1 and p-p38 levels. Vaspin can up-regulate the proliferation and steroidogenesis of rat luteal cells and reduce apoptosis, which may be related to the influence of MEK/MAPK activity.
"Global Health Diet" im Alpenraum?
Creators: name: Schönberg, Sonja
Publisher: name: Berner Fachhochschule BFH, Departement Gesundheit
Year: 2020

description: Die EAT-Lancet-Comission hat kürzlich die «Global Health Diet» publiziert. Diese vereint die Gesundheit der Menschen und die Gesundheit der Umwelt. Im Master-Studiengang Life Sciences – Food, Nutrition and Health entstand eine Projektarbeit, die eine mögliche Umsetzung der «Global Health Diet» im Schweizer Alpenraum untersucht.
International prevalence measurement of care problems: results
Creators: name: Halfens, Ruud J.
name: Meesterberends, Esther
name: Van Nie-Visser, No�Emi C.
name: Lohrmann, Christa
name: Schonherr, Silvia
name: Meijers, Judith M.
name: Hahn, Sabine
name: Vangelooven, C.
name: Schols, J. M.
Publisher: name: Wiley-Blackwell - STM
Year: 2013

description: AIM: This report describes the results from the last international prevalence measurement of care problems in the Netherlands, Austria and Switzerland, including the course of the prevalence rates during the past 4 years. BACKGROUND: Basic care problems such as pressure ulcers, malnutrition and falls occur frequently in healthcare organizations. Measuring these care problems provides insight into their occurrence, and, while a measurement is included of the prevention, treatment and structural quality indicators, this gives institutions the possibility of improving their care regarding these care problems. DESIGN: An annual cross-sectional multicentre study. METHOD: The prevalence measurement of care problems is conducted annually on one specific day in different healthcare settings, among which are hospitals and care homes. Data are collected by means of a comprehensive, standardized questionnaire that comprises three levels: institutional, ward/department and patient level. RESULTS: Besides general characteristics of patients, results are presented for prevalence rates, prevention, treatment and quality indicators regarding each care problem for each country.
ВОЯГА ЕТМАГАНЛАР ТОМОНИДАН СОДИР ЭТИЛАЁТГАН ҲУҚУҚБУЗАРЛИКЛАР ВА УЛАРНИ ОЛДИНИ ОЛИШНИНГ ЎЗИГА ХОС ХУСУСИЯТЛАРИ
Creators: name: Қулдашев, Абдумалик
Publisher: name: Zenodo
Year: 2024

description: Мазкур мақолада вояга етмаганлар томонидан содир этилаётган ҳуқуқбузарликларнинг илмий таҳлили ҳамда ҳуқуқбузарликларнинг профилактикаси тушунчалари ва маҳалла ҳамда кенг жамоатчилик вакиллари, тегишли идора масъулларини жалб этган ҳолда профилактик тадбирларни тизимли амалга ошириш мақсадга мувофиқ деган фикр илгари сурилган.
Acuros® CQD® SWIR Camera Applications Note - High Resolution Infrared Reflectography of Painting Underdrawings
Creators: name: Küffner, Markus
name: Palmbach, Cornelius
Publisher: name: SWIR Vision Systems Inc.
Year: 2020

description: Infrared reflectography of paintings is used to make underlying layers clearly visible in contrast. IR radiation penetrates the upper layers of the painting and is reflected by the primer. The underdrawing, which is made with carbonaceous colorants on the primer, absorbs IR radiation and shows a strong contrast. The 2 MP sensor of the camera in combination with a lens with a short minimum working distance allows the realization of a very high resolution, which is important for the possibility to evaluate the underdrawing. The effective achievable resolution is therefore dependent on both components, sensor and lens.
Un éprouvant début dans la vie
Creators: name: Daniels, Carmen
name: Eggimann, Maria
name: Hobi, Bettina
name: Bernet, Madeleine
Publisher: name: Schweizer Berufsverband der Pflegefachfrauen und Pflegefachmänner
Year: 2024

description: Lorsqu’un bébé est hospitalisé sitôt après sa naissance, les parents traversent une période de terrible incertitude avec un sentiment d’impuissance et de perte de contrôle. Pour permettre la construction de l’attachement malgré cette rude situation, il est important d’impliquer les parents dans les soins et la prise en charge des nourrissons vulnérables.
Effects of Physical and Mental Fatigue on Postural Sway and Cortical Activity in Healthy Young Adults
Creators: name: Gebel, Arnd
name: Busch, Aglaja
name: Stelzel, Christine
name: Hortóbagyi, Tibor
name: Granacher, Urs
Publisher: name: Frontiers Research Foundation
Year: 2022

description: Physical fatigue (PF) negatively affects postural control, resulting in impaired balance performance in young and older adults. Similar effects on postural control can be observed for mental fatigue (MF) mainly in older adults. Controversial results exist for young adults. There is a void in the literature on the effects of fatigue on balance and cortical activity. Therefore, this study aimed to examine the acute effects of PF and MF on postural sway and cortical activity. Fifteen healthy young adults aged 28 ± 3 years participated in this study. MF and PF protocols comprising of an all-out repeated sit-to-stand task and a computer-based attention network test, respectively, were applied in random order. Pre and post fatigue, cortical activity and postural sway (i.e., center of pressure displacements [CoPd], velocity [CoPv], and CoP variability [CV CoPd, CV CoPv]) were tested during a challenging bipedal balance board task. Absolute spectral power was calculated for theta (4–7.5 Hz), alpha-2 (10.5–12.5 Hz), beta-1 (13–18 Hz), and beta-2 (18.5–25 Hz) in frontal, central, and parietal regions of interest (ROI) and baseline-normalized. Inference statistics revealed a significant time-by-fatigue interaction for CoPd (p = 0.009, d = 0.39, Δ 9.2%) and CoPv (p = 0.009, d = 0.36, Δ 9.2%), and a significant main effect of time for CoP variability (CV CoPd: p = 0.001, d = 0.84; CV CoPv: p = 0.05, d = 0.62). Post hoc analyses showed a significant increase in CoPd (p = 0.002, d = 1.03) and CoPv (p = 0.003, d = 1.03) following PF but not MF. For cortical activity, a significant time-by-fatigue interaction was found for relative alpha-2 power in parietal (p < 0.001, d = 0.06) areas. Post hoc tests indicated larger alpha-2 power increases after PF (p < 0.001, d = 1.69, Δ 3.9%) compared to MF (p = 0.001, d = 1.03, Δ 2.5%). In addition, changes in parietal alpha-2 power and measures of postural sway did not correlate significantly, irrespective of the applied fatigue protocol. No significant changes were found for the other frequency bands, irrespective of the fatigue protocol and ROI under investigation. Thus, the applied PF protocol resulted in increased postural sway (CoPd and CoPv) and CoP variability accompanied by enhanced alpha-2 power in the parietal ROI while MF led to increased CoP variability and alpha-2 power in our sample of young adults. Potential underlying cortical mechanisms responsible for the greater increase in parietal alpha-2 power after PF were discussed but could not be clearly identified as cause. Therefore, further future research is needed to decipher alternative interpretations.
Tra Napoli e Parigi: Storie di una migrazione libraria
Creators: name: Giovani, Giulia
Publisher: name: LIM
Year: 2021

description: Le biblioteche musicali del Conservatorio della Pietà dei Turchini di Napoli e del Conservatoire di Parigi videro la luce negli stessi anni con il fine comune di servire la didattica e divenire luoghi cardine per la costruzione di una memoria collettiva. Partendo dall’illustrazione dei rapporti tra i due centri urbani, questo volume analizza i primi decenni di vita delle due biblioteche guardando alle differenti modalità di accrescimento delle collezioni, mostrando l’interesse generale dei francesi per il patrimonio musicale napoletano e individuando le carte che migrarono dalla città vesuviana verso Parigi in età napoleonica. Attraverso l’analisi di documenti archivistici, partiture, carteggi degli emissari napoleonici in Italia in larga parte inediti, è narrato un capitolo di storia musicale intrecciato a doppio filo con le operazioni di sottrazione di opere d’arte attuate dai funzionari di Napoleone in Italia.
Wie attraktiv ist die Sozialhilfe als Arbeitsfeld?
Creators: name: Matti, Thomas
name: Pfiffner, Roger
Publisher: name: Schweizerische Konferenz für Sozialhilfe
Year: 2021

description: Im Sozialwesen intensiviert sich der Wettbewerb um talentierte Fachkräfte. Eine neue Studie hat deshalb untersucht, wie attraktiv die Sozialhilfe im Vergleich zu anderen Arbeitsfeldern ist und welche Studienabgängerinnen und -abgänger sich für die Tätigkeit in einem Sozialdienst interessieren.
Trained men show lower cortisol, heart rate and psychological responses to psychosocial stress compared with untrained men
Creators: name: Heinrichs, Markus
name: Rimmele, Ulrike
name: Zellweger, Bea Costa
name: Marti, Bernard
name: Seiler, Roland
name: Mohiyeddini, Changiz
name: Ehlert, Ulrike
Publisher: name: Elsevier
Year: 2007
Subjects: Physical activity Sports Exercise Psychosocial stress Cortisol Heart rate

description: Physical activity has proven benefits for physical and psychological well-being and is associated with reduced responsiveness to physical stress. However, it is not clear to what extent physical activity also modulates the responsiveness to psychosocial stress. The purpose of this study was to evaluate whether the reduced responsiveness to physical stressors that has been observed in trained men can be generalized to the modulation of physiological and psychological responses to a psychosocial stressor. Twenty-two trained men (elite sportsmen) and 22 healthy untrained men were exposed to a standardized psychosocial laboratory stressor (Trier Social Stress Test). Adrenocortical (salivary free cortisol levels), autonomic (heart rate), and psychological responses (mood, calmness, anxiety) were repeatedly measured before and after stress exposure. In response to the stressor, cortisol levels and heart rate were significantly increased in both groups, without any baseline differences between groups. However, trained men exhibited significantly lower cortisol and heart rate responses to the stressor compared with untrained men. In addition, trained men showed significantly higher calmness and better mood, and a trend toward lower state anxiety during the stress protocol. On the whole, elite sportsmen showed reduced reactivity to the psychosocial stressor, characterized by lower adrenocortical, autonomic, and psychological stress responses. These results suggest that physical activity may provide a protective effect against stress-related disorders.
Papunega Gnezdilov et Bourgoin
Creators: name: Gnezdilov, V. M.
name: Cesne, M. Le
name: Soulier-Perkins, A.
name: Bourgoin, T.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Issidae
Papunega

description: Papunega Gnezdilov et Bourgoin, gen. nov.
Type species: Papunega magnifacies sp. nov.
Description. Metope wide, with thick subapical transverse carina (Figs 2, 14). Metope convex (visible from above), but in the same time flattened together with clypeus. Lateral margins (keels) of metope raised, slightly leafshaped above pedicel. Metopoclypeal suture distinct, complete, widely convex. Pedicel elongate and cylindrical. Coryphe transverse, usually with two large tubercles near its posterior margin besides of median line (Figs 1, 13). Paradiscal fields of pronotum behind the eyes very narrow. No ocelli. Fore wings elongate (Figs 3, 15), weakly narrowing to rounded apices, without hypocostal plate. R 2 M 4–5 CuA 2, with many transverse veins. Hind wings well developed, 3-lobed (Fig. 4). Hind tibia with 2 lateral spines distally and 7 spines apically. First metatarsomere with 2 lateral and 5–7 intermediate (in entire row) spines apically.
Etymology. Generic name is derived from the combination of words " Papua ", "New", and " Guinea ". Gender feminine.
Comparison. Related to the genus Tetrica Stål (type species: Tetrica fusca Stål, 1870), but distinguished as follows: metope with tiny or without median carina (strong median carina which runs through whole metope (Figs 20, 21) from its upper margin in T. fusca); postclypeus without median carina (distinct carina in T. fusca (Fig. 21); fore wings without hypocostal plate (present in T. fusca (Fig. 22); basal cell of fore wings oval and elongated (wide in T. fusca (Fig. 22)).
description: Published as part of Gnezdilov, V. M., Cesne, M. Le, Soulier-Perkins, A. & Bourgoin, T., 2015, New Guinean Issidae: description of new taxa in a poorly known island fauna (Hemiptera, Fulgoroidea) in Zootaxa 3904 (1), DOI: 10.11646/zootaxa.3904.1.4, http://zenodo.org/record/240866
Additional file 8: of Differential cytotoxicity induced by the Titanium(IV)Salan complex Tc52 in G2-phase independent of DNA damage
Creators: name: Pesch, Theresa
name: Schuhwerk, Harald
name: Wyrsch, Philippe
name: Immel, Timo
name: Dirks, Wilhelm
name: BĂźrkle, Alexander
name: Huhn, Thomas
name: Beneke, Sascha
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Additional Methods. (PDF 144 kb)
Additional file 3: of Dhurrin metabolism in the developing grain of Sorghum bicolor (L.) Moench investigated by metabolite profiling and novel clustering analyses of time-resolved transcriptomic data
Creators: name: Nielsen, Lasse
name: Stuart, Peter
name: PiÄManovĂĄ, Martina
name: Rasmussen, Simon
name: Olsen, Carl
name: Harholt, Jesper
name: MĂ¸Ller, Birger
name: Bjarnholt, Nanna
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Computational Biology

description: Clustering analysis of transcript expression profiles divided into 20 groups of similar expression. (PDF 245 kb)
Additional file 7: of Differential cytotoxicity induced by the Titanium(IV)Salan complex Tc52 in G2-phase independent of DNA damage
Creators: name: Pesch, Theresa
name: Schuhwerk, Harald
name: Wyrsch, Philippe
name: Immel, Timo
name: Dirks, Wilhelm
name: Bürkle, Alexander
name: Huhn, Thomas
name: Beneke, Sascha
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Analysis of rapid free cytosolic Ca2 + -shifts in HeLa tumor cells and VH7 normal fibroblasts. Cells were processed as suggested by the manufacturer. Tc52 or Tc53 or solvent control (CTR) was administered to the cells and Ca2 + -dependent increase in fluorescence of Fluo4-NW-dye was measured. Significant increase in fluorescence is an indicator for cell death signaling. A: Increase in free cytosolic Ca2+ in HeLa cells. Both concentrations show significant and rapid increase in Ca2+ signal, reaching after 5 sec 4 and 5.5 RFU above CTR and after 10 sec 6.5 and 5 RFU above CTR, whereas control and Tc53 values stay low. B: No significant increase in free cytosolic Ca2+ in VH7 cells. Only the 10 μM Tc52 exposure samples display initially a mild increase (1 RFU above CTR), which is lost after 10 sec (0 RFU above CTR). As summary, rapid Ca2+ increase is indicative for cytotoxicity of Tc52 in HeLa cells, whereas its toxicity is negligible in VH7 normal fibroblasts, in line with other data. (PDF 1085 kb)
Classifying Numbers from EEG Data – Which Neural Network Architecture Performs Best?
Creators: name: Selvasingham, Sugeelan
name: Denecke, Kerstin
Publisher: name: IOS Press
Year: 2022
Subjects: Convolutional neural networks
EEG
P300
Classification

description: This paper presents a comparison of deep learning models for classifying P300 events, i.e., event-related potentials of the brain triggered during the human decision-making process. The evaluated models include CNN, (Bi | Deep | CNN-) LSTM, ConvLSTM, LSTM + Attention. The experiments were based on a large publicly available EEG dataset of school-age children conducting the “Guess the number”-experiment. Several hyperparameter choices were experimentally investigated resulting in 30 different models included in the comparison. Ten models with good performance on the validation data set were also automatically optimized with Grid Search. Monte Carlo Cross Validation was used to test all models on test data with 30 iterations. The best performing model was the Deep LSTM with an accuracy of 77.1% followed by the baseline (CNN) 76.1%. The significance test using a 5x2 cross validation paired t-test demonstrated that no model was significantly better than the baseline. We recommend experimenting with other architectures such as Inception, ResNet and Graph Convolutional Network.
Additional file 1: of Epidemiology and outcome ofÂ Clostridium difficileÂ infections in patients hospitalized in Internal Medicine:Â findings from the nationwide FADOI-PRACTICE study
Creators: name: Cioni, Giorgio
name: Viale, Pierluigi
name: Frasson, Stefania
name: Cipollini, Francesco
name: Menichetti, Francesco
name: Petrosillo, Nicola
name: Brunati, Sergio
name: Spigaglia, Patrizia
name: Vismara, Chiara
name: Bielli, Alessandra
name: Barbanti, Fabrizio
name: Landini, Giancarlo
name: Panigada, Grazia
name: Gussoni, Gualberto
name: Bonizzoni, Erminio
name: Gesu, Giovanni
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: List of local Ethics Committees which approved the study. (DOC 25Â kb)
Team efficacy and leadership in managing aggressive situations in the general hospital setting: A qualitative descriptive analysis of focus groups with ward managers.
Creators: name: Heckemann, Birgit
name: Siegrist-Dreier, Sandra
name: Thilo, Friederike J.S.
name: Hahn, Sabine
Publisher: name: Wiley-Blackwell - STM
Year: 2020

description: Aims and objectives This study explores the perception and issues regarding the ability of nursing teams to manage patient and visitor aggression in clinical practice, from ward managers’ perspectives. Background Patient and visitor aggression causes substantial human suffering and financial damage in healthcare organizations. Nurse managers are key persons for developing their teams’ efficacy in dealing with patient and visitor aggression. However, their perception of patient and visitor aggression in clinical practice has rarely been explored, and issues relating to team management in this context are underinvestigated. Design A secondary, qualitative thematic analysis of focus group interviews. Methods Five focus groups consisting of a total of 30 ward and deputy ward managers from five Swiss hospitals were interviewed with audio recording between December 2015 and January 2016. Since the recordings were rich in additional content exceeding the primary research question, a secondary analysis was conducted to answer the questions: (1) Which factors influence team efficacy in regard to patient and visitor aggression? (2) What are the implications for nurse leadership? The Consolidated Criteria for Reporting Qualitative Research were followed in the conduct and reporting of this study. Results Three themes emerged from our analysis: (1) contextual factors (organizational safety culture and collaboration), (2) influences from within the team (team culture, nursing aggression and general management principles) and (3) implications for nurse leadership. Conclusions Managing patient and visitor aggression is a challenge for nurse managers. A team's ability to prevent, de‐escalate and debrief after PVA incidents is an important leadership task in which ward managers are neither supported in nor trained for within their organizations. Relevance to clinical practice Nurse managers in general hospitals require more support to enable their teams to cope effectively with patient and visitor aggression. Policy and guideline implementation need to be prioritized.
Additional file 3. of Implementing Kanyini GAP, a pragmatic randomised controlled trial in Australia: findings from a qualitative study
Creators: name: Hueiming Liu
name: Massi, Luciana
name: Eades, Anne-Marie
name: Howard, Kirsten
name: Peiris, David
name: Redfern, Julie
name: Usherwood, Tim
name: Cass, Alan
name: Patel, Anushka
name: Jan, Stephen
name: Tracey-Lea Laba
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Coding framework. (DOCX 21 kb)
Papunega fasciatifrons Melichar 1906, comb. nov.
Creators: name: Gnezdilov, V. M.
name: Cesne, M. Le
name: Soulier-Perkins, A.
name: Bourgoin, T.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Issidae
Papunega
Papunega fasciatifrons

description: Papunega fasciatifrons (Melichar, 1906), comb. nov.
(Figs 24, 25)
Tetrica fasciatifrons Melichar, 1906: 298.
Note. The photos of Tetrica fasciatifrons syntype (Figs 24, 25) deposited in the Hungarian Natural History Museum (Budapest, Hungary) were examined. The species is placed in the genus Papunega gen. nov. as it corresponds to the diagnostic characters of the genus mentioned above.
We do not include currently Tetrica suffusa Melichar, 1906 to the genus Papunega gen. nov. as this species is characterised by coryphe with distinctly convex anterior margin and glib fore wings with multibranched median vein (Melichar, 1906, Fig. 72 and unpublished data of V.M. Gnezdilov). The taxonomic position of this species will be solved later (Gnezdilov, in preparation).
description: Published as part of Gnezdilov, V. M., Cesne, M. Le, Soulier-Perkins, A. & Bourgoin, T., 2015, New Guinean Issidae: description of new taxa in a poorly known island fauna (Hemiptera, Fulgoroidea) in Zootaxa 3904 (1), DOI: 10.11646/zootaxa.3904.1.4, http://zenodo.org/record/240866
Povertà tra i minorenni : quadro generale e proposte di soluzione in Svizzera
Creators: name: Chiapparini, Emanuela
Publisher: name: Dipartimento economia aziendale, sanità e sociale (Manno)
Year: 2020

description: Nonostante la Svizzera sia una società benestante, la povertà colpisce più persone di quante ne siano percepite pubblicamente. In special modo, la povertà tra i minorenni è diffusa e un tabù. Il presente articolo intende fornire una spiegazione di cosa si intende oggi per povertà in Svizzera, nonché una descrizione del fenomeno della povertà tra i minorenni con l’ausilio di determinati criteri e dati quantitativi. Verranno inoltre presentate due soluzioni attuali e innovative: le scuole continuative e la partecipazione a strutture e processi politici.
Additional file 2: of Frequent but asymmetric niche shifts in Bulbophyllum orchids support environmental and climatic instability in Madagascar over Quaternary time scales
Creators: name: Gamisch, Alexander
name: Fischer, Gunter
name: Comes, Hans
Publisher: name: Figshare
Year: 2016
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Developmental Biology
subject: Computational Biology

description: Rankings of loadings for the first two principal components (PC1, PC2) of 604 Bulbophyllum clade C (plus outgroup) locality values of 20 environmental variables (altitude, bioclim 1â  19). (DOC 40 kb)
Gaeolaelaps Evans & Till 1966
Creators: name: Nemati, Alireza
name: Mohseni, Mastaneh
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Mesostigmata
Laelapidae
Gaeolaelaps

description: Genus Gaeolaelaps Evans & Till, 1966
Hypoaspis (Gaeolaelaps) Evans & Till, 1966: 159.
Type species Laelaps aculeifer Canestrini, 1884, by original designation.
description: Published as part of Nemati, Alireza & Mohseni, Mastaneh, 2013, Two new species of Gaeolaelaps (Acari: Laelapidae) from Iran, pp. 71-82 in Zootaxa 3750 (1) on page 72, DOI: 10.11646/zootaxa.3750.1.5, http://zenodo.org/record/285342
CCIs' needs for indoor filming using RPAS. AiRT project
Creators: name: De-Miguel-Molina, Blanca
name: Segarra-Oña, Marival
name: Santamarina-Campos, Virginia
name: de-Miguel-Molina, Mária
name: Stephan Kröner
name: Xavier Mas-Barberá
name: Carabal-Montagud, Mª Ángeles
Publisher: name: Zenodo
Year: 2017

description: This document describes the creative industries’ needs for aerial indoor filming and photography using RPAS, commonly also known as drones. To do so, three sessions in different countries, England, Belgium and Spain using the Participatory Action Research (PAR) technique, commonly applied for the analysis of focus groups were held. The PAR tool, that consist on collecting information through a semi-structured group interview process, is led by a moderator that can intervene from a low to a higher level, depending on the dynamics of the discussion. This methodology is very useful to gather information on a specific topic. Informants (experts) were chosen strategically from 13 different sectors to guarantee that all the Creative Industry’s (CI) needs are detected, including experienced drone pilots working in different CI sectors (40% of the informants). Then, information was codified and analysed using the qualitative analysis software QDA Miner by Provalis Research, which is especially designed to analyse interviews and focus group transcriptions. Following ethnographic rules, the names of participants were encoded so they remain anonymous. Results and conclusions are presented in this document, deliverable D2.1, and also in the deliverable D2.2 “Ethical, Security and Safety issues concerning RPAS use in confined spaces”.
description: With contributions from: Clearhead, Pozyx and the 20 participants in the focus groups who are experts in 13 sectors of creative industries. Design and layout: Virginia Santamarina (Universitat Politècnica de València). Photography: Clearhead Media Ltd. (UK) Diagrams, tables and images: Blanca de Miguel, Marival Segarra and Virginia Santamarina (Universitat Politècnica de València)
Femtosecond Laser-Induced Periodic Surface Structures in Titanium-Doped Diamond-like Nanocomposite Films: Effects of the Beam Polarization Rotation
Creators: name: Pimenov, Sergei M.
name: Zavedeev, Evgeny V.
name: Jaeggi, Beat
name: Neuenschwander, Beat
Publisher: name: MDPI
Year: 2023
Subjects: Ti-DLN films Femtosecond laser ablation Linear polarization Laser-induced periodic surface structures (LIPSS) Lateral force microscopy

description: We study the properties of laser-induced periodic surface structures (LIPSS) formed on 12 titanium-doped diamond-like nanocomposite (DLN) a-C:H:Si:O films during ablation processing 13 with linearly-polarized beams of a visible femtosecond laser (wavelength 515 nm, pulse duration 14 320 fs, pulse repetition rates 100 kHz-2 MHz, scanning beam velocity 0.05-1 m/s). The studies are 15 focused on (i) laser ablation characteristics of Ti-DLN films at different pulse frequencies and con-16 stant fluence close to the ablation threshold, (ii) effects of the polarization angle rotation on the 17 properties of low spatial frequency LIPSS (LSFL), and (iii) nanofriction properties of the ‘rotating’ 18 LIPSS using atomic force microscopy (AFM) in a lateral force mode. It is found that (i) all LSFL are 19 oriented perpendicular to the beam polarization direction, so being rotated with the beam polari-20 zation, and (ii) LSFL periods are gradually changed from 360±5 nm for ripples parallel to the beam 21 scanning direction to 420±10 nm for ripples formed perpendicular to the beam scanning. The ob-22 tained results are discussed in the frame of the surface plasmon polaritons model of the LIPSS 23 formation. Also, the findings of the nanoscale friction behavior, dependent on the LIPSS orientation 24 relative to the AFM tip scanning direction, are presented and discussed.
Additional file 3: of Diversity, evolution and expression profiles of histone acetyltransferases and deacetylases in oomycetes
Creators: name: Wang, Xiao-Wen
name: Guo, Li-Yun
name: Han, Miao
name: Shan, Kun
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: Primers for real-time qPCR used in this study. (DOC 156Â kb)
Additional file 8: of Dhurrin metabolism in the developing grain of Sorghum bicolor (L.) Moench investigated by metabolite profiling and novel clustering analyses of time-resolved transcriptomic data
Creators: name: Nielsen, Lasse
name: Stuart, Peter
name: PiÄManovĂĄ, Martina
name: Rasmussen, Simon
name: Olsen, Carl
name: Harholt, Jesper
name: MĂ¸Ller, Birger
name: Bjarnholt, Nanna
Publisher: name: Figshare
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Plant Biology

description: Dendrogram showing specific clusters from the hierarchical clustering of expressed UGTs in sorghum. (PDF 153 kb)
Additional file 3: of Differential cytotoxicity induced by the Titanium(IV)Salan complex Tc52 in G2-phase independent of DNA damage
Creators: name: Pesch, Theresa
name: Schuhwerk, Harald
name: Wyrsch, Philippe
name: Immel, Timo
name: Dirks, Wilhelm
name: Bürkle, Alexander
name: Huhn, Thomas
name: Beneke, Sascha
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Detection of DNA strand break markers poly(ADP-ribosyl)ation and γH2AX in HeLa and VH7. A: PAR can be weakly detected in HeLa cells about 5 min after application of 500 μM H2O2 in cell culture medium, peaking at 10 min, and signals disappear completely after 60 min. Later time points are not depicted. Phosphorylated H2AX appears after 10 min incubation as a pan-nuclear signal, with pronounced characteristic foci formation after 6 h. B: PAR can be weakly detected in VH7 cells about 5 min after application of 500 μM H2O2 in cell culture medium, peaking at 30 min and signals disappear completely after 60 min. Later time points are not depicted. Phosphorylated H2AX appears after 10 min incubation as a pan-nuclear signal, with less well pronounced characteristic foci formation after 60 min. C: H2AX and-tubulin detection in a time-course from 0 min (Ctr) to 1440 min (24 h) after application of 500 μM H2O2 (H), 10 μM Tc52 (52) or 10 μM Tc53 (53) to HeLa cells. Signal-ratio evaluation of γH2AX/tubulin is presented in the lower panel. γH2AX formation in H2O2 treated samples is evident after 30 min and increases over time. Only after 24 h of Tc52 treatment, a mild increase in γH2AX is detectable, concurrent with the onset of cell death (Fig. 1a). (PDF 1085 kb)