cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Afferent Visual Pathway Affection in Patients with PMP22 Deletion-Related Hereditary Neuropathy with Liability to Pressure Palsies
Creators: name: Brandt, Alexander U.
name: Meinert-Bohn, Elena
name: Rinnenthal, Jan Leo
name: Zimmermann, Hanna
name: Mikolajczak, Janine
name: Oberwahrenbrock, Timm
name: Papazoglou, Sebastian
name: Pfuller, Caspar F.
name: Schinzel, Johann
name: Tackenberg, Bjorn
name: Paul, Friedemann
name: Hahn, Katrin
name: Bellmann-Strobl, Judith
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background The PMP22 gene encodes a protein integral to peripheral myelin. Its deletion leads to hereditary neuropathy with liability to pressure palsies (HNPP). PMP22 is not expressed in the adult central nervous system, but previous studies suggest a role in CNS myelin development. The objective of this study was to identify potential structural and functional alterations in the afferent visual system in HNPP patients. Methods Twenty HNPP patients and 18 matched healthy controls (HC) were recruited in a cross-sectional study. Participants underwent neurological examination including visual acuity, visual evoked potential (VEP) examination, optical coherence tomography (OCT), and magnetic resonance imaging with calculation of brain atrophy, regarding grey and white matter, and voxel based morphometry (VBM), in addition answered the National Eye Institute’s 39-item Visual Functioning Questionnaire (NEI- VFQ). Thirteen patients and 6 HC were additionally examined with magnetic resonance spectroscopy (MRS). Results All patients had normal visual acuity, but reported reduced peripheral vision in comparison to HC in the NEI-VFQ (p = 0.036). VEP latency was prolonged in patients (P100 = 103.7±5.7 ms) in comparison to healthy subjects (P100 = 99.7±4.2 ms, p = 0.007). In OCT, peripapillary retinal nerve fiber layer thickness RNFL was decreased in the nasal sector (90.0±15.5 vs. 101.8±16.5, p = 0.013), and lower nasal sector RNFL correlated with prolonged VEP latency (Rho = -0.405, p = 0.012). MRS revealed reduced tNAA (731.4±45.4 vs. 814.9±62.1, p = 0.017) and tCr (373.8±22.2 vs. 418.7±31.1, p = 0.002) in the visual cortex in patients vs. HC. Whole brain volume, grey and white matter volume, VBM and metabolites in a MRS sensory cortex control voxel did not differ significantly between patients and HC. Conclusion PMP22 deletion leads to functional, metabolic and macro- structural alterations in the afferent visual system of HNPP patients. Our data suggest a functional relevance of these changes for peripheral vision, which warrants further investigation and confirmation.
title: JSON Implementation of Time-Frequency Radio Catalogues: TFCat
Creators: name: Cecconi, Baptiste
name: Taylor, Mark
name: Bonnin, Xavier
name: Loh, Alan
Publisher: name: PADC/MASER
Year: 2021

description: TFCat (Time-Frequency Catalogue) is a data interchange format based on JSON. It defines several types of JSON objects and the manner in which they are combined to represent data about time-frequency features of a time spectrogram (a.k.a. dynamic spectrum), their properties, and their temporal and spectral extents.
Magmatic-hydrothermal and wall rock alteration at the Lake Shore gold deposit, Kirkland Lake, Ontario.
Creators: name: Hicks, Kevin Douglas.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Geology.

description: The Lake Shore Au deposit lies in the Kirkland Lake Au camp, the second largest Archean camp in North America. The deposit is hosted in an alkaline to sub-alkaline intrusive complex composed of augite syenite, syenite, feldspar porphyry and quartz-feldspar porphyry. Feldspar and quartz-feldspar porphyry are the latest of the intrusive phases within the Lake Shore property and host over two-thirds of the Au in the camp. Detailed petrography and geochemistry of the feldspar porphyry indicate that it is predominantly a quartz-monzodiorite. The primary mineralogy of this unit consists of plagioclase, orthoclase, biotite, and hornblende, with accessory magnetite, apatite, titanite, monazite, and zircon. Miarolitic cavities within this unit suggest a relatively shallow level of emplacement as well as an H$\sb2$O-rich nature for the magma. Four successive alteration facies are recognized within the feldspar porphyry. The concentric nature of the later three alteration facies as zones about the auriferous veins may be the result of several overprinting, chemically distinct hydrothermal events, each of which penetrated the wall rocks to subsequent decreasing depths. A second possibility is that they are the result of a fluid which evolved as it penetrated the wall rocks. (Abstract shortened by UMI.)
A review of the key issues associated with the commercialization of biobanks
Creators: name: Caulfield, Timothy
name: Burningham, Sarah
name: Joly, Yann
name: Master, Zubin
name: Shabani, Mahsa
name: Borry, Pascal
name: Becker, Allan
name: Burgess, Michael
name: Calder, Kathryn
name: Critchley, Christine
name: Edwards, Kelly
name: Fullerton, Stephanie M.
name: Gottweis, Herbert
name: Hyde-Lay, Robyn
name: Illes, Judy
name: Isasi, Rosario
name: Kato, Kazuto
name: Kaye, Jane
name: Knoppers, Bartha
name: Lynch, John
name: McGuire, Amy
name: Meslin, Eric
name: Nicol, Dianne
name: O'Doherty, Kieran
name: Ogbogu, Ubaka
name: Otlowski, Margaret
name: Pullman, Daryl
name: Ries, Nola
name: Scott, Chris
name: Sears, Malcolm
name: Wallace, Helen
name: Zawati, Ma'n H.
Publisher: name: Swinburne
Year: 2024

description: This 'issues paper' was generated through a 'virtual workshop process' over the course of severalmonths.The authors first outlined relevant issues and key literature. A draft was then distributed, comments were received, and a revised draft was circulated among authors for approval.The use of a 'virtual workshop process' shaped both the tone and coverage of this article, though we hope in a way that still provides a detailed and useful summary of central issues on this topic.We believe that this paper-the collaborative work of globally situated ELSI researchers-exemplifies 'ELSI 2.0' (Jane Kaye et al., Research Priorities. ELSI 2.0 for Genomics and Society, 336 Science 673 (2012)).
title: Teacher beliefs about Chinese character acquisition via computer-assisted language learning
title: a multiple case study
titleType: Subtitle
Creators: name: Chen, Yue
Publisher: name: University of Iowa
Year: 2024

description: Teacher beliefs have received substantial attention particularly in Chinese as a world language context due to the Chinese language proficiency challenges, Chinese character complexity, and cultural barriers. With the development of cutting-edge technology, Computer-Assisted Language Learning (CALL) has played a pivotal role in Chinese language acquisition, empowering learners with interactive tools, online resources, immersive experience, and more that enhance Chinese language learning. However, there have been limited in-depth research exploring teacher beliefs about Chinese character acquisition via CALL. This multiple case study drew upon the theoretical framework of language teacher cognition (Borg, 2015). The research questions included: 1) What are teachers’ beliefs and perceptions about character acquisition via CALL? 2) How do teachers implement CALL when teaching characters? 3) What benefits and challenges do teachers perceive when incorporating CALL in character acquisition? This study comprised three secondary Chinese teachers in the United States. These teachers located in various regions, with a diverse teaching experience. Data were collected via Zoom, including first individual interviews about teacher’s perceptions and stated practices, classroom observations, second individual interviews about teacher’s perspectives on benefits and challenges of characters acquisition via CALL, and a focus group discussion where teachers sharing their knowledge, experiences, and beliefs. Thematic analysis was employed to analyze the qualitative data.
description: The findings suggested that teachers view CALL as valuable, beneficial, enhancing student engagement in character acquisition which have evidenced in the literature (e.g., Chen et al., 2013; Hsiao et al., 2015; Zhan & Cheng, 2014). Moreover, the teachers also believed that CALL increased their productivity and reduced their workload. Nonetheless, challenges such as limited access to CALL resources and insufficient training have been identified (e.g., Zhang et al., 2014). The study's outcomes contribute to Chinese language education, provide insights for effective CALL integration in character acquisition, and provide pedagogical implications to various stakeholders.
3933884.pdf
Creators: name: Esmann, Martin
name: Lamberti, Fabrice
name: Harouri, Abdelmounaim
name: Lanco, Loïc
name: SAGNES, ISABELLE
name: Favero, Ivan
name: Aubin, Guy
name: Gomez-Carbonell, Carmen
name: Lemaitre, Aristide
name: Krebs, Olivier
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Photoelastic model of the anti-Stokes Brillouin scattering cross-section, polarization dependence of the Brillouin signal, spatial filtering of the Brillouin signals in planar and pillar microcavities, and backscattering in superlattices
Assessment of potential :1 programmed ribosomal frameshifting by the human cytokine receptor IL-7Rα
Creators: name: Jackson, Jennie Lynne
Publisher: name: University of British Columbia
Year: 2025

description: Translation is an important step in the flow of genetic information from DNA, to RNA, to protein. Yet, translational fidelity is not always maintained. One example of a recoding event is programmed ribosomal frameshifts (PRF). PRF is mainly utilized by viruses, yeast, or bacteria, where the outcome of a shifted reading frame may result in carboxy-terminally extended fusion proteins or mRNA degradation. In this way, PRF is a form of translational control. The regulation of cytokine receptors, including at the translational level, is valuable to understand due to their importance in immune cell signaling. Interleukin-7 receptor α (IL-7Rα) in particular, which has major roles in proper immune system development and function, is known to be tightly regulated. IL-7Rα has well-documented examples of transcriptional and post-translational regulation, but post-transcriptional and translational regulation remain areas requiring further study. Indeed, IL-7Rα, as well as IL-2Rγ – the other subunit of the heterodimeric IL-7 receptor – were computationally predicted to contain -1 PRF motifs in their mRNA. Initial in vitro testing with reporter constructs expressed in HeLa cells was promising, but HeLa cells are not the best model for intrinsic IL-7Rα signaling pathways. Therefore, I sought to test the putative IL-7Rα PRF motif in a physiologically relevant context. I hypothesized that translational regulation of the cytokine receptor IL-7Rα via -1 PRF modulated its expression in human T cells. Using flow cytometry, I developed a single cell level assay so that -1 PRF could be compared between different T cell subsets, such as naïve, effector, or memory, within the same sample. Through various techniques, I also characterized impaired and/or abnormal Renilla luciferase expression by our IL-7Rα PRF dual luciferase reporter plasmid. Overall, despite being unable to resolve whether IL-7Rα expression is regulated by -1 PRF in human T cells, the flow cytometry PRF assay remains an adaptable tool to study PRF at the single cell level.
Microscopic Theory of the Elastic Shear Modulus and Length-Scale-Dependent Dynamic Re-Entrancy Phenomena in Very Dense Sticky Particle Fluids
Creators: name: Mutneja, Anoop
name: Schweizer, Kenneth S
Publisher: name: arXiv
Year: 2024
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We apply the hybrid Projectionless Dynamic Theory (hybrid PDT) formulation of the Elastically Collective Nonlinear Langevin Equation (ECNLE) activated dynamics approach to study dense fluids of sticky spheres with short range attractions. Of special interest is the problem of non-monotonic evolution with attraction strength of the elastic modulus ("re-entrancy") at high packing fractions far beyond the ideal mode coupling theory (MCT) nonergodicity boundary. The dynamic force constraints explicitly treat the bare attractive forces that drive transient physical bond formation, while a projection approximation is employed for the singular hard-sphere potential. The resultant interference between repulsive and attractive forces contribution to the dynamic vertex results in the prediction of localization length and elastic modulus re-entrancy, qualitatively consistent with experiments. The non-monotonic evolution of the alpha time predicted by ECNLE theory with the hybrid PDT approach is explored in depth as a function of packing fraction, attraction strength, and range. Isochronal dynamic arrest boundaries based on activated relaxation display the classic non-monotonic glass melting form. Comparisons of these results with the corresponding predictions of ideal MCT and the ECNLE and NLE activated theories based on projection reveal large qualitative differences. The consequences of stochastic trajectory fluctuations on intra-cage single particle dynamics with variable attraction strengths are also studied. Large dynamical heterogeneity effects in attractive glasses are properly captured. These include a rapidly increasing non-Gaussian parameter with packing fraction and a non-monotonic evolution with attraction strength, in accord with recent simulations. Extension of the microscopic theoretical approach to treat double yielding in attractive glass nonlinear rheology is possible.
description: Accepted in Softmatter
A nonlinear dynamical systems model for DRP1 oligomerization dependent mitochondrial fission
Creators: name: Leinheiser, Anna Kay
Publisher: name: University of Iowa
Year: 2023
Subjects: public abstract
Biochemistry

description: The overall objective of this project is to identify regulatory parameters in the molecular mechanisms impacting mitochondrial dynamics, specifically fission/fusion balance. These regulatory parameters will help therapeutic target selection with the goal of modulating mitochondrial dynamics without inducing extreme hyperfission or hyperfusion. Cellular stress results in fission/fusion imbalance which further leads to reduced energy production and programmed cell death. There is a critical need in mitochondrial biology to understand the molecular mechanisms that coordinate this complex process. Using multi-scale mathematical modeling, we investigate a DRP1 oligomerization dependent fission mechanism in order to identify regulatory parameters for mitochondrial fission.
description: Based on Dr. Colleen Mitchell’s preliminary mathematical modeling of in vivo and in vitro mitochondrial dynamics which focused on the balance between fission and fusion, the rate of mitochondrial fission is the ideal control point for the distribution of mitochondrial size. We hypothesize
description: the association and dissociation rate constants for dynamin related protein one (Drp1), a GTPase necessary for fission, and oligomerization on the outer mitochondrial membrane (OMM) are critical for determining the fission rate.
Changes in the area at risk over time and following nicardipine administration in the dog.
Creators: name: Sandhu, Reena.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Health Sciences, Pharmacology.

description: A major determinant of myocardial infarct size (IS) is the amount of myocardium at risk of infarcting (AAR). When determined in vivo, AAR size depends upon the size of the normal perfusion territory of the occluded bed and upon collateral flow. We tested the hypothesis that AAR size can change spontaneously or after therapy. $\sp{\rm 99m}$Tc macroaggregates (MAC) or Monastral Blue Dye (MBD) were used to define the AAR. After MBD, the hearts were excised, sliced, photographed and incubated in Nitro-Blue tetrazolium to identify the infarct. After rephotographing, the slices were autoradiographed. The two sets of photographs and autoradiographs were used for planimetery of the AAR as defined by MBD, infarct size, and AAR as defined by MAC respectively. In all 3 groups there was a correlation between the AAR sizes as determined by the two techniques. In this model, the AAR size does not change either spontaneously or following Nicardipine. Nicardipine also does not appear to substantially limit infarct size. (Abstract shortened by UMI.)
Social marketing to address attitudes and behaviours related to preventable injuries in British Columbia, Canada
Creators: name: Smith, Jennifer
name: Zheng, Xin
name: Lafreniere, Kevin
name: Pike, Ian, 1958-
Publisher: name: BMJ
Year: 2021

description: Background Social marketing is a tool used in the domain of public health for prevention and public education. Because injury prevention is a priority public health issue in British Columbia, Canada, a 3-year consultation was undertaken to understand public attitudes towards preventable injuries and mount a province-wide social marketing campaign aimed at adults aged 25–55 years. Methods Public response to the campaign was assessed through an online survey administered to a regionally representative sample of adults within the target age group between 1 and 4 times per year on an ongoing basis since campaign launch. A linear regression model was applied to a subset of this data (n=5186 respondents) to test the association between exposure to the Preventable campaign and scores on perceived preventability of injuries as well as conscious forethought applied to injury-related behaviours. Results Campaign exposure was significant in both models (preventability: β=0.27, 95% CI 0.20 to 0.35; conscious thought: β=0.24, 95% CI 0.13 to 0.35), as was parental status (preventability: β=0.12, 95% CI 0.03 to 0.21; conscious thought: β=0.18, 95% CI 0.06 to 0.30). Exposure to the more recent campaign slogan was predictive of 0.47 higher score on conscious thought (95% CI 0.27 to 0.66). Discussion This study provides some evidence that the Preventable approach is having positive effect on attitudes and behaviours related to preventable injuries in the target population. Future work will seek to compare these data to other jurisdictions as the Preventable social marketing campaign expands to other parts of Canada.
Recurrent features of translation in Canada: A corpus-based study
Creators: name: Williams, Donna A
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Language, General.

description: Based on the theory of translation universals, the general hypothesis that translated texts are distinguishable from non-translated texts by certain recurrent features of translation has been tested in recent contributions to Corpus-based Translation Studies. This hypothesis assumes that translation will leave similar traces in different languages. Major corpus-based studies have recently investigated three specific hypothetical recurrent features of translation (normalization, explicitation, and simplification). However, each of these research projects has hypothesized only one recurrent feature of translation at a time, using mainly literary, Anglo-European corpora, and using English as the sole target language of the translated texts. In the present study, all three of the above previously-studied recurrent features of translation are hypothesized and investigated, along with a fourth (levelling-out), which has not been the subject of previous study. Characteristics of translated and non-translated texts are compared in both English and French: appropriately for study of hypothetical "universal" features, the present research is carried out on target texts in more than one language. Our corpora consist of texts taken from Government of Canada Web sites; they constitute a broad sample of non-literary texts. Specific techniques of analysis are adapted from the literature, and where appropriate, new techniques are devised. WordSmith (versions 3 and 4) was the primary tool used for corpus analysis. The empirical evidence gathered in the present research supports the hypotheses of normalization and explicitation as recurrent features of translation into both English and French, but does not support the hypotheses of simplification and levelling-out. There is some indication that translated texts in both English and French tend to be more difficult to read (according to the standards of readability indices), an unexpected but interesting finding. All of these results must be interpreted in the light of future corpus-based study of recurrent features of translation, and it is recommended that a standardized protocol for recording the attributes of future comparable corpora should be adopted.
Occupants of memory: War in twentieth-century Canadian fiction
Creators: name: Webb, Peter
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Literature, Modern.
subject: Literature, Canadian (English).

description: "Occupants of Memory: War in Twentieth-Century Canadian Fiction" examines key novels and short stories about wartime and post-war experience spanning nine decades. Beginning with Sara Jeannette Duncan's The Imperialist (1904) and ending with Timothy Findley's "Stones" (1988), this dissertation juxtaposes works by such well-known Canadian authors as Ralph Connor, Hugh MacLennan, and L.M. Montgomery with lesser-known but important works by William Allister, Charles Yale Harrison, Edward McCourt, and Colin McDougall. Unlike previous studies of Canadian war literature, most of which focus on an individual author, a single war, or a particular theme, this dissertation argues that war fiction is a tradition in which authors influence, reflect, and counter one another throughout the century. Discourses of social memory and nationalism/anti-nationalism provide a theoretical basis for discussion, and descriptions of major events from the South African War, through the two world wars, to the Cold War form an historical context for authors and their works. References to European and American war literature and its critics show Canadian works to be comparable to, yet different from, their international counterparts. Particularly notable is the way in which Canadian works emphasize a dichotomy between romance and realism, rarely broaching the high modernism that is the hallmark of many international works. Occupants of Memory lays the groundwork for a broad critical discourse of Canadian war literature and its related subjects.
Photometric redshift analysis in the Dark Energy Survey Science Verification data
Creators: name: Sánchez, C.
name: Carrasco Kind, M.
name: Lin, H.
name: Miquel, R.
name: Abdalla, F. B.
name: Amara, A.
name: Banerji, M.
name: Bonnett, C.
name: Brunner, R.
name: Capozzi, D.
name: Carnero, A.
name: Castander, F. J.
name: da Costa, L. A N
name: Cunha, C.
name: Fausti, A.
name: Gerdes, D.
name: Greisel, N.
name: Gschwend, J.
name: Hartley, W.
name: Jouvel, S.
name: Lahav, O.
name: Lima, M.
name: Maia, M. A G
name: Martí, P.
name: Ogando, R. L C
name: Ostrovski, F.
name: Pellegrini, P.
name: Rau, M. M.
name: Sadeh, I.
name: Seitz, S.
name: Sevilla-Noarbe, I.
name: Sypniewski, A.
name: de Vicente, J.
name: Abbot, T.
name: Allam, S. S.
name: Atlee, D.
name: Bernstein, G.
name: Bernstein, J. P.
name: Buckley-Geer, E.
name: Burke, D.
name: Childress, M. J.
name: Davis, T.
name: DePoy, D. L.
name: Dey, A.
name: Desai, S.
name: Diehl, H. T.
name: Doel, P.
name: Estrada, J.
name: Evrard, A.
name: Fernández, E.
name: Finley, D.
name: Flaugher, B.
name: Frieman, J.
name: Gaztanaga, E.
name: Glazebrook, Karl
name: Honscheid, K.
name: Kim, A.
name: Kuehn, K.
name: Kuropatkin, N.
name: Lidman, C.
name: Makler, M.
name: Marshall, J. L.
name: Nichol, R. C.
name: Roodman, A.
name: Sánchez, E.
name: Santiago, B. X.
name: Sako, M.
name: Scalzo, R.
name: Smith, R. C.
name: Swanson, M. E C
name: Tarle, G.
name: Thomas, D.
name: Tucker, D. L.
name: Uddin, S. A.
name: Valdés, F.
name: Walker, A.
name: Yuan, F.
name: Zuntz, J.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: We present results from a study of the photometric redshift performance of the Dark Energy Survey (DES), using the early data from a Science Verification period of observations in late 2012 and early 2013 that provided science-quality images for almost 200 sq. deg. at the nominal depth of the survey. We assess the photometric redshift (photo-z) performance using about 15 000 galaxies with spectroscopic redshifts available from other surveys. These galaxies are used, in different configurations, as a calibration sample, and photo-z's are obtained and studied using most of the existing photo-z codes. A weighting method in a multidimensional colour-magnitude space is applied to the spectroscopic sample in order to evaluate the photo-z performance with sets that mimic the full DES photometric sample, which is on average significantly deeper than the calibration sample due to the limited depth of spectroscopic surveys. Empirical photo-z methods using, for instance, artificial neural networks or random forests, yield the best performance in the tests, achieving core photo-z resolutions σ68 ∼ 0.08. Moreover, the results from most of the codes, including template-fitting methods, comfortably meet the DES requirements on photo-z performance, therefore, providing an excellent precedent for future DES data sets.
A New Characterization Technique to Analyze Concentrator Photovoltaic Optical System Performance
Creators: name: Mcvey White, Patrick
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Solar
Engineering
Concentrator Photovoltaics
Energy Yield
Characterization
Optics
CPV Systems
Irradiance

description: Concentrator photovoltaics is a promising renewable energy technology, especially for utility or large-scale deployments. Like all new technologies, it has obstacles and setbacks to overcome. More specifically, the optics in a concentrator photovoltaics system introduce non-uniform spatial and spectral illumination on the cell, which can change under different operating conditions. This work was put together to discover a new characterization technique capable of analyzing the performance of a concentrator photovoltaics and provide insight to the field on what is happening within the system, linking modeling results seen in the literature to these experimental outcomes. The thesis is composed of three journal papers written by the candidate, who’s contributions are outlined at the beginning of each chapter. In order to study the illumination profiles on the cells, a new method to characterize the optical components had to be developed. Previous version lacked the ability to control the temperature of the lens and had low spectral resolution of the irradiance profiles. To improve, a novel indoor measurement method was developed capable of spectrally imaging concentrator photovoltaics optics and recreate outdoor operating conditions in a controllable environment. With the calibrated system, our test-bench is capable of measuring the spectral distribution with a 10μm2 resolution and characterizing the output of a system to within 3%. Exploiting this experimental technique, the individual effects of module misalignment, cell to primary distance, and lens temperature was studied for three leading technologies associated with the three generations of concentrator photovoltaics optical architectures. Focusing on Fresnel-based concentrator optics, the performance of silicone on a glass module without a secondary optic is the most sensitive to operating conditions, where lens temperature can decrease the absolute efficiency resulting in a difference of 11% in the annual energy yield. The next two generations have secondary optics but are designed slightly differently. The truncated inverted pyramid, designed independently of the primary optic, favoured higher lens temperature values and there was only a difference of 1% in the energy yield calculation. The primary and secondary optics in the 4-fold Fresnel-Kohler are designed together, due to new development tools, and showed the highest stability under the different operating conditions, demonstrating that concentrator photovoltaics is on the right track to overcoming its onset issue. As the technology matures, future designs can improve on the issues characterized within this thesis.
Spin-orbit-splitting-driven nonlinear Hall effect in NbIrTe4
Creators: name: Lee, Ji-Eun
name: Wang, Aifeng
name: Chen, Shuzhang
name: Kwon, Minseong
name: Hwang, Jinwoong
name: Cho, Minhyun
name: Son, Ki-Hoon
name: Han, Dong-Soo
name: Choi, Jun Woo
name: Kim, Young Duck
name: Mo, Sung-Kwan
name: Petrovic, Cedomir
name: Hwang, Choongyu
name: Park, Se Young
name: Jang, Chaun
name: Ryu, Hyejin
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The Berry curvature dipole (BCD) serves as a one of the fundamental contributors to emergence of the nonlinear Hall effect (NLHE). Despite intense interest due to its potential for new technologies reaching beyond the quantum efficiency limit, the interplay between BCD and NLHE has been barely understood yet in the absence of a systematic study on the electronic band structure. Here, we report NLHE realized in NbIrTe4 that persists above room temperature coupled with a sign change in the Hall conductivity at 150 K. First-principles calculations combined with angle-resolved photoemission spectroscopy (ARPES) measurements show that BCD tuned by the partial occupancy of spin-orbit split bands via temperature is responsible for the temperature-dependent NLHE. Our findings highlight the correlation between BCD and the electronic band structure, providing a viable route to create and engineer the non-trivial Hall effect by tuning the geometric properties of quasiparticles in transition-metal chalcogen compounds.
Ultrafast charge-carrier dynamics of copper oxide nanocrystals
Creators: name: Holzman, Jonathan F.
name: Born, Brandon
name: Geoffroy-Gagnon, Simon
name: Collier, Christopher Michael
name: Krupa, Jeffrey D. A.
name: Hristovski, Ilija R.
Publisher: name: American Chemical Society
Year: 2018

description: In this work, a detailed investigation is carried out on copper oxide, in the form of cupric oxide (CuO) nanocrystals. Particular attention is paid to the bandstructure and ultrafast charge-carrier dynamics. Transient absorption spectroscopy is carried out with an above-bandgap pump beam and below-bandgap probe beam to glean insight on the relaxation and recombination dynamics of the CuO nanocrystals at various pump fluences. Three time constants are apparent. The first time constant varies with pump fluence from 330 fs to 630 fs, and it is attributed to momentum relaxation via carrier-carrier scattering in the valence band as well as exciton-exciton annihilation. The second time constant is constant at 2 ps, and it is attributed to energy relaxation via carrier-phonon scattering within the valence band. The third time constant is constant at 50 ps, and it is attributed to trapping and recombination, due to the high density of trap states within the CuO nanocrystals. Such findings lay the foundation for future studies and applications of the emerging CuO material system.
Instrument de-synthesis using wavelets
Creators: name: Pelletier, Emile
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Mathematics.

description: Our point of departure is the concept of 'additive synthesis', which is the traditional explanation for the individual of 'timbre' or 'colour' of the sound of the various musical instruments. When an instrument sounds a note, one hears the note as if by itself, but this is not what is physically happening. What is in fact occurring is a complex waveform featuring a collection of harmonic frequencies, referred to as the spectrum. A synthesizer attempts to imitate the sound of a particular instrument by replicating the amplitudes of its harmonics. We use the term 'de-synthesis' to refer to the inverse procedure, computerized instrument identification. We describe an experiment that we designed and executed with M ATLAB to explore the hypothesis that a computer will be able to recognize an instrument by its characteristic timbre. The idea of applying wavelets to analyze music comes naturally since music consists of sound waves, and wavelets are wave shaped functions. We propose a mathematical model that can take certain musical instrument's attack and decay features into account that utilizes Malvar wavelets: Super Malvar wavelets. Super wavelets are superpositions of ordinary wavelets in some linear combination that can be treated as a wavelet in itself. (Abstract shortened by UMI.)
Autonomous measurement of phytoplankton physiology and productivity using fast repetition rate fluorometry
Creators: name: Sezginer, Yayla
Publisher: name: University of British Columbia
Year: 2025

description: Through photosynthesis, phytoplankton form the base of marine food webs and drive atmospheric CO₂ uptake through the marine biological carbon pump. Monitoring phytoplankton photosynthetic responses to changing environmental conditions is thus critical to predicting ecosystem feedbacks to climate change. Fast Repetition Rate fluorometry (FRRF) offers rapid measurements of phytoplankton photo-physiology and photosynthetic electron transport rates (ETR), which represent the ultimate source of metabolic energy for carbon fixation. This thesis aims to address several physiological and methodological considerations that presently limit the widespread use of FRRF for high resolution in-situ measurements of phytoplankton ETR. These challenges include diverging approaches to calculate ETR (Chapter 2), the influence of pre-measurement sample handling practices and variable photo-acclimation states on ETR measurements (Chapter 3), and variability in the stoichiometry between ETR and downstream carbon fixation (Chapter 4). The field-based studies presented in this work illustrate how natural light and nutrient gradients influence photo-physiology, FRRF signatures and their interpretation. Results presented in Chapter 2 reveal that the coherence between ETR estimates derived from different algorithms varies with underlying phytoplankton photo-physiology. Additionally, ETR estimates are directly affected by photoprotective non-photochemical quenching (NPQ) that dissipates excess absorbed photo-energy as heat. Chapter 3 investigates the effects of photo-physiology and photo-acclimation states on NPQ relaxation time-scales, providing useful insights for field protocol design for high resolution ETR acquisition. In addition to NPQ, phytoplankton mitigate dangerous accumulation of reductant by diverting electrons towards alternative sinks, decoupling electron transport rates from downstream carbon fixation. Chapter 4 illustrates how this effect manifests as a hyperbolic relationship between ETR and carbon fixation, offering a new approach to predict carbon fixation rates from ETR. The work presented in this thesis addresses specific details of FRRF application, as well as broader questions regarding energy transfer efficiencies between photosynthetic processes, supporting the expansion of high-resolution FRRF-based estimates of biological carbon uptake.
Antidepressant dosage taken by patients with bipolar disorder: Factors associated with irregularity
Creators: name: Bauer, Rita
name: Glenn, Tasha
name: Alda, Martin
name: Sagduyu, Kemal
name: Marsh, Wendy
name: Grof, Paul
name: Munoz, Rodrigo
name: Murray, Greg
name: Ritter, Philipp
name: Lewitzka, Ute
name: Severus, Emanuel
name: Whybrow, Peter
name: Bauer, Markus
Publisher: name: Swinburne
Year: 2024

description: Background This study analyzed regularity in the daily dosage of antidepressants taken by patients with bipolar disorder and identified the factors associated with irregularity. Methods Daily self-reported medication dosage taken and mood ratings were available from 144 patients who received treatment as usual. All 144 patients took the same antidepressant for at least 100 days. One hundred eleven of these patients were also taking a mood stabilizer. Approximate entropy (ApEn) was used to measure serial regularity in daily dosage. Regularity is the tendency that values within a time series remain the same on incremental comparisons. Drug holidays (missing three or more consecutive days) were also determined. Generalized estimating equations (GEE) were used to estimate if any demographic or clinical variables were associated with regularity. Results Although the mean percent of days missing doses was only 18.6%, there was a wide range of regularity in the daily antidepressant dosage. Drug holidays were common, occurring in 41% of the analyses. Factors significantly associated with irregularity were as follows: total number of psychotropic medications (p=0.005), pill burden (p=0.005), and depression (p=0.015). Neither the percent of days missing doses nor the drug holidays were associated with any demographic or clinical factors. For patients taking both antidepressants and mood stabilizers, there was no significant difference in regularity in daily dosage between these drugs. Discussion There can be considerable irregularity in daily dosage despite a low percent of days missing doses. Medication regimen complexity and depressed mood are associated with increased irregularity. Daily regularity in drug dosage may be more dependent on the individual than on the specific drug. Research on the clinical impact of irregularity in daily dosage of antidepressants is needed.
title: Exploración ecográfica del tobillo: técnica y hallazgos normales.
Creators: name: Megales Navarro, Rafael Javier
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Education
subject: Ultrasound
subject: Musculoskeletal soft tissue

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Mostrar la sistemática de exploración,
anatomía ecográfica,
hallazgos normales,
así como las principales indicaciones del estudio ecográfico del...
On the dynamics of amphibious vehicles in surf and shallow water
Creators: name: Swafford, Michael C.
Publisher: name: University of Iowa
Year: 2024
Subjects: Amphibious Vehicle
Hexapod
Shallow Water
Surf Zone
System Identification

description: Amphibious craft are a unique class of vehicle -- having the ability to both operate on land as well as in water -- with broad applications in the littoral region of the ocean that include cargo connectors, search and rescue, and coastal monitoring amongst others. Interest in autonomous amphibious vehicles to perform these tasks has grown significantly in recent years due to the decrease in risk to human life in austere environments, persistent monitoring, and freeing up people to perform more critical tasks.Any amphibious vehicle operating in the naval context, at the very least, must pass through the surf zone, a region of the ocean that extends from the point of wave breaking to the shoreline \parencite{Smith2003,Svendsen1992}. When waves break on a beach, they dissipate large amounts of energy as turbulence, driving currents both onshore and offshore\parencite{Michallet2011, Smith2003,Svendsen1992}. These circumstances present a clear challenge to vessel controllability and survivability \parencite{Arnold2020,Behara2020}.
description: Amphibious craft, like many other cross-country ranging ground vehicles, must contend with shallow-water environments both in the surf zone and during water fording. Despite the wide applicability of fording, the literature on the topic mirrors that of surf zone studies. There is a lack of systematic experimental studies on the hydrodynamics of ground vehicles operating in shallow-water.
description: Furthermore, recent advances in both experimental devices and system identification unlock the potential for rapid and accurate identification of model parameters that form the basis for the formulation of automatic control models for marine vehicles.
description: Presented in this thesis are a number of investigations on amphibious vehicles aimed at developing the experimental methods and for the development of dynamic models. Experiments cover surf zone transit of a free-running craft, where results were used to validate numerical codes as well as found the phasing of the first wave encounter and momentum entering the surf zone determined the subsequent wave encounters. A shallow-water experimental campaign was conducted to investigate the hydrodynamic forces on a ground vehicle during water fording. The results of this study were used to validate a machine learning model and to find a scaling relationship for the total resistance coefficient. Finally, a system identification methodology was developed that used phase-optimized orthogonal multisine excitations to determine the added mass and damping matrices of a submerged body. These model parameters can then be extended to contemporary vehicle-specific maneuvering models, where automatic control schemes may be used with full system knowledge to drive an uncrewed underwater vehicle autonomously.
Non-Hermitian polariton-photon coupling in a perovskite open microcavity
Creators: name: Kędziora, Mateusz
name: Król, Mateusz
name: Kapuściński, Piotr
name: Sigurðsson, Helgi
name: Mazur, Rafał
name: Piecek, Wiktor
name: Szczytko, Jacek
name: Matuszewski, Michał
name: Opala, Andrzej
name: Piętka, Barbara
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Exploring the non-Hermitian properties of semiconductor materials for optical applications is at the forefront of photonic research. However, the selection of appropriate systems to implement such photonic devices remains a topic of debate. In this work, we demonstrate that a perovskite crystal, characterized by its easy and low-cost manufacturing, when placed between two distributed Bragg reflectors with an air gap, can form a natural double microcavity. This construction shows promising properties for the realisation of novel, tunable non-Hermitian photonic devices through strong light-matter coupling. We reveal that such a system exhibits double-coupled polariton modes with dispersion including multiple inflection points. Owing to its non-Hermiticity, our system exhibits nonreciprocal properties and allows for the observation of exceptional points. Our experimental studies are in agreement with the theoretical analysis based on coupled mode theory and calculations based on transfer matrix method.
description: Accepted manuscript (AM)
title: Anatomía radiológica intracraneal de los pares craneales
Creators: name: Fernández Martín, Ana Isabel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology peripheral nerve
subject: MR
subject: CT
subject: Education

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo de este poster esfamiliarizar al radiológo con la apariencia y el recorrido normal intracraneal de los pares craneales,
mediante RM y TC.El motivo peticionario de unporcentaje importante de pruebas deneuroimagenes descartar patología...
Upregulation of Immunoproteasome Subunits in Myositis Indicates Active Inflammation with Involvement of Antigen Presenting Cells, CD8 T-Cells and IFNγ
Creators: name: Ghannam, Khetam
name: Martinez-Gamboa, Lorena
name: Spengler, Lydia
name: Krause, Sabine
name: Smiljanovic, Biljana
name: Bonin, Marc
name: Bhattarai, Salyan
name: Grützkau, Andreas
name: Burmester, Gerd-R.
name: Häupl, Thomas
name: Feist, Eugen
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Objective In idiopathic inflammatory myopathies (IIM) infiltration of immune cells into muscle and upregulation of MHC-I expression implies increased antigen presentation and involvement of the proteasome system. To decipher the role of immunoproteasomes in myositis, we investigated individual cell types and muscle tissues and focused on possible immune triggers. Methods Expression of constitutive (PSMB5, -6, -7) and corresponding immunoproteasomal subunits (PSMB8, -9, -10) was analyzed by real-time RT-PCR in muscle biopsies and sorted peripheral blood cells of patients with IIM, non-inflammatory myopathies (NIM) and healthy donors (HD). Protein analysis in muscle biopsies was performed by western blot. Affymetrix HG-U133 platform derived transcriptome data from biopsies of different muscle diseases and from immune cell types as well as monocyte stimulation experiments were used for validation, coregulation and coexpression analyses. Results Real-time RT-PCR revealed significantly increased expression of immunoproteasomal subunits (PSMB8/-9/-10) in DC, monocytes and CD8+ T-cells in IIM. In muscle biopsies, the immunosubunits were elevated in IIM compared to NIM and exceeded levels of matched blood samples. Proteins of PSMB8 and -9 were found only in IIM but not NIM muscle biopsies. Reanalysis of 78 myositis and 20 healthy muscle transcriptomes confirmed these results and revealed involvement of the antigen processing and presentation pathway. Comparison with reference profiles of sorted immune cells and healthy muscle confirmed upregulation of PSMB8 and -9 in myositis biopsies beyond infiltration related changes. This upregulation correlated highest with STAT1, IRF1 and IFNγ expression. Elevation of T-cell specific transcripts in active IIM muscles was accompanied by increased expression of DC and monocyte marker genes and thus reflects the cell type specific involvement observed in peripheral blood. Conclusions Immunoproteasomes seem to indicate IIM activity and suggest that dominant involvement of antigen processing and presentation may qualify these diseases exemplarily for the evolving therapeutic concepts of immunoproteasome specific inhibition.
Magnetic field control of silver nanoparticle formation
Creators: name: Maguire, Steven
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Chemistry, Analytical.

description: Silver nanoparticles can be readily generated in micellar environments by ketyl radicals formed from the photoreduction of benzophenone in the presence of a suitable hydrogen donor. The yield of these ketyl radicals can be increased by extending the lifetime of the triplet radical pair through Zeeman splitting of the triplet sublevels in an externally applied magnetic field. This provides control over the rate of photogeneration of nanoparticles under very mild conditions. The rate of photogeneration can be monitored by the distinctive surface plasmon resonance absorption around 420 nm. In this work, micelles of sodium dodecyl sulphate (SDS) were employed, and 1,4-cyclohexadiene (1,4-CHD), an excellent hydrogen donor, was used to promote the generation of ketyl radicals. When benzophenone and a silver salt are added to this system and it is irradiated in the presence of a magnetic field, the rate of appearance of the plasmon band is enhanced. In addition to serving as a hydrogen donor, 1,4-CHD also has a stabilising influence on the nanoparticles, adsorbing onto the surface and preventing aggregation. 1,4-CHD added to a solution of nanoparticles synthesised without the diene present will even break up existing aggregates.