cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The state of Illinois obstetric hemorrhage project: pre-project and post-training examination scores
Creators: name: Jones, Robin L.
name: Geller, Stacie
name: Wong, Cynthia A.
name: Scott, Shirley
name: Walzer, Jennifer
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Medicine

description: Objective: The Illinois Department of Public Health mandated that all clinicians who provide care to obstetric patients participate in the Illinois Obstetric Hemorrhage Project. The aim of the current report is to describe change in knowledge among providers engaged in the project, as assessed by pre- and post-tests.Methods: The project, implemented 2008 to 2010, included four components: a written 25-item multiple-choice examination (pre-test), a didactic lecture, skill stations (for teaching blood loss estimation), and a simulation drill and debriefing. Participants completed a post-test 6 months later. Pre- and post-test examination scores were compared.Results: Data from 95 hospitals are included in this analysis (9456 paired test results). The proportion of participants who scored ≥88% correct answers increased from 10.9% on the pre-test to 49.1% on the post-test (p p Conclusions: The Illinois Obstetric Hemorrhage Project was successful in improving knowledge of obstetric hemorrhage in a large number of providers with different expertise and experience levels. Further long-term study is essential to determine whether the skills acquired during the Project contribute to improved obstetric hemorrhage outcomes for the women of Illinois.
Longitudinal effects of menopausal hormone treatments on platelet characteristics and cell-derived microvesicles
Creators: name: Miller, Virginia M.
name: Lahr, Brian D.
name: Bailey, Kent R.
name: Heit, John A.
name: S. Mitchell Harman
name: Muthuvel Jayachandran
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Hematology
subject: Developmental Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Biotechnology
subject: Pharmacology
subject: Physiology
subject: Genetics
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Activated platelets serve as a catalyst for thrombin generation and a source of vasoactive and mitogenic factors affecting vascular remodeling. Oral menopausal hormone treatments (MHT) may carry greater thrombotic risk than transdermal products. This study compared effects of oral and transdermal MHT on platelet characteristics, platelet proteins, and platelet-derived microvesicles (MV) in recently menopausal women. Platelets and MV were prepared from blood of a subset of women (n = 117) enrolled in the Kronos Early Estrogen Prevention Study prior to and after 48 months of treatment with either oral conjugated equine estrogen (0.45 mg/day), transdermal 17β-estradiol (50 µg/day), each with intermittent progesterone (200 mg/day for 12 days a month), or placebo pills and patch. Platelet count and expression of platelet P-selectin and fibrinogen receptors were similar across groups. An aggregate measure of 4-year change in vasoactive and mitogenic factors in platelet lysate, by principle component analysis, indicated significantly lower values in both MHT groups compared to placebo. Increases in numbers of tissue factor positive and platelet-derived MV were significantly greater in the transdermal compared to placebo group. MHT was associated with significantly reduced platelet content of vasoactive and mitogenic factors representing a potential mechanism by which MHT may affect vascular remodeling. Various hormonal compositions and doses of MHT could differentially regulate nuclear transcription in bone marrow megakaryocytes and non-genomic pathways in circulating platelets thus determining numbers and characteristics of circulating MV. Thrombotic risk associated with oral MHT most likely involves liver-derived inflammatory/coagulation proteins rather than circulating platelets per se.
Säkularismus in Indien-Theorie und Praxis
Creators: name: Engineer, Ashgar Ali
name: Geilen, Dirk
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Additional file 1 of Short‑ and long‑term outcomes after laparoscopic and open pancreatoduodenectomy for elderly patients: a propensity score‑matched study
Creators: name: Xu, Shuai
name: Deng, Xin
name: Wang, Shulin
name: Yu, Guangsheng
name: Liu, Jun
name: Gong, Wei
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
Perceptions and responses to climate policy risks among California farmers
Creators: name: Niles, Meredith
name: Lubell, Mark
name: Haden, Van Ryan
Publisher: name: figshare
Year: 2015
Subjects: subject: Personality, Social and Criminal Psychology
subject: Applied Psychology
subject: Sociology
subject: FOS: Sociology
subject: Climate Science

description: This paper considers how farmers perceive and respond to climate change policy risks, and suggests that understanding these risk responses is as important as understanding responses to biophysical climate change impacts. Based on a survey of 162 farmers in California, we test three hypotheses regarding climate policy risk: (1) that perceived climate change risks will have a direct impact on farmer's responses to climate policy risks, (2) that previous climate change experiences will influence farmer's climate change perceptions and climate policy risk responses, and (3) that past experiences with environmental policies will more strongly affect a farmer's climate change beliefs, risks, and climate policy risk responses. Using a structural equation model we find support for all three hypotheses and furthermore show that farmers’ negative past policy experiences do not make them less likely to respond to climate policy risks through participation in a government incentive program. We discuss how future research and climate policies can be structured to garner greater agricultural participation. This work highlights that understanding climate policy risk responses and other social, economic and policy perspectives is a vital component of understanding climate change beliefs, risks and behaviors and should be more thoroughly considered in future work.
Dithizone-modified graphene oxide nano-sheet as a sorbent for pre-concentration and determination of cadmium and lead ions in food
Creators: name: Zadeh, Hamid Reza Moghadam
name: Ahmadvand, Parvaneh
name: Behbahani, Ali
name: Amini, Mostafa M.
name: Sayar, Omid
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biochemistry

description: Graphene oxide nano-sheet was modified with dithizone as a novel sorbent for selective pre-concentration and determination of Cd(II) and Pb(II) in food. The sorbent was characterised by various analytical methods and the effective parameters for Cd(II) and Pb(II) adsorption were optimised during this work. The high adsorption capacity and selectivity of this sorbent makes the method capable of fast determinations of the Cd(II) and Pb(II) content in complicated matrices even at μg l−1 levels using commonly available instrumentation. The precision of this method was
Landwirtschaft und Ernährungssicherung in Indien
Creators: name: Van Dillen, Susanne
name: Weber, Eberhard
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Wirtschaftsplanung und Politik in Indien- 1947-1997
Creators: name: Mehrotra, Deepti Priya
name: Geilen, Dirk
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Nepal als Hindustan
Creators: name: Dixit, Kanak Mani
name: Basting, Bernd
name: Geilen, Dirk
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Kruppel like factor 16 promotes lung adenocarcinoma progression by upregulating lamin B2
Creators: name: Jiao, Xiaodan
name: Gao, Weinian
name: Ren, Hongxin
name: Wu, Yanning
name: Li, Tiezhi
name: Li, Shujun
name: Yan, Hongjiang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Lung cancer is one of the most common causes of cancer-related death. In the past decade, the treatment and diagnosis of lung cancer have progressed significantly in early efforts to promote the survival of lung cancer patients. Kruppel like factor 16 (KLF16) is a zinc finger transcription factor that regulates a diverse array of developmental events and cellular processes. KLF16 is involved in the progression of various cancer types. However, the role of KLF16 in the development of lung cancer remains unknown. In this study, KLF16 was overexpressed in lung cancer samples. KLF16 downregulation inhibited lung cancer cell proliferation and migration. Conversely, KLF16 overexpression promoted lung cancer cell growth and invasion. Mechanistically, the expression level LMNB2 was suppressed by KLF16 knockdown and was promoted by KLF16 overexpression. The overall survival of patients with high LMNB2 levels was poor. Luciferase assays showed that KLF16 promoted the transcription activity of LMNB2 gene. Concomitantly, the expression level of LMNB2 was also higher in lung adenocarcinoma (LUAD) than in normal tissues, and its knockdown or overexpression can reverse the effect of KLF16 overexpression or knockdown on lung cancer cell proliferation, migration, and even tumorigenesis, indicating that LMNB2 also functions as an oncogene. In conclusion, KLF16 can be used as a potential therapeutic and preventive biomarker in lung cancer treatment and prognosis by actively regulating the expression of LMNB2.
-Verprügelt, beraubt, deportiert- Tibetische Flüchtlinge an Nepals Grenze
Creators: name: Tüting, Ludmilla
Publisher: name: Südasien
Year: 2024

description: --
description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Kabinett-Umbildung und Umstellungen im Zentralkomitee des 'Nepali Congress'
Creators: name: Redaktion, Die
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Predicting Early Data Revisions to U.S. GDP and the Effects of Releases on Equity Markets
Creators: name: Clements, Michael P.
name: Galvão, Ana Beatriz
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: The effects of data uncertainty on real-time decision-making can be reduced by predicting data revisions to U.S. GDP growth. We show that survey forecasts efficiently predict the revision implicit in the second estimate of GDP growth, but that forecasting models incorporating monthly economic indicators and daily equity returns provide superior forecasts of the data revision implied by the release of the third estimate. We use forecasting models to measure the impact of surprises in GDP announcements on equity markets, and to analyze the effects of anticipated future revisions on announcement-day returns. We show that the publication of better than expected third-release GDP figures provides a boost to equity markets, and if future upward revisions are expected, the effects are enhanced during recessions.
Interview: Calcuttas Verkehrsprobleme
Creators: name: Gupta, Anish
name: Clemens, Jürgen
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
A new monoterpene glucoside and complete assignments of dihydroflavonols of Pulicaria jaubertii: potential cytotoxic and blood pressure lowering activity
Creators: name: Ehab A. Ragab
name: Raafat, Mohamed
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: One new monoterpene glucoside and five dihydroflavonols were isolated for the first time from the aerial parts of Pulicaria jaubertii and identified as p-menthane-2-O-β-D-glucopyranoside [1], dihydroquercetin (taxifolin) [2], 7,3′-di-O-methyltaxifolin [3], 3′-O-methyltaxifolin [4], 7-O-methyltaxifolin (padmatin) [5] and 7-O-methyl-dihydrokampferol (7-O-methylaromadenderin) [6]. The structures of these compounds were unambiguously assigned on the basis of NMR spectroscopic data (1H, 13C, DEPT, HSQC, HMBC) and MS analysis. 2D-NMR methods required revision of assignments of H-6 and H-8 for dihydroflavonol compounds. Possible cytotoxic activity as well as blood pressure (BP) lowering activity were tested. The alcoholic extract showed cytotoxic activity against prostate carcinoma (PC-3), breast carcinoma (MCF-7) and hepatocellular carcinoma (HepG-2) human cell lines with IC50 19.1, 20.0 and 24.1 μg, respectively. The higher dose levels of the alcoholic extract significantly reduced normal BP of rats in a dose-dependent manner.
Begegnung mit dem Gottesdenker Tissa Balasuriya
Creators: name: Seiterich-Kreuzkamp, Thomas
Publisher: name: Südasien
Year: 2024

description: Südasien, Bd. 17 Nr. 7-8 (1997): 50 Jahre Unabhängigkeit- Wirtschaftliche Entwicklung und Ernährungssicherheit
Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications
Creators: name: Ford, Kevin A.
name: Ryslik, Gregory
name: Jasleen Sodhi
name: Halladay, Jason
name: Dolo Diaz
name: Dambach, Donna
name: Masuda, Melisa
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Pharmacology
subject: Genetics
subject: FOS: Biological sciences
subject: Biochemistry

description: Cytochrome P450 2D6 (CYP2D6) is a polymorphic enzyme responsible for metabolizing approximately 25% of all drugs. CYP2D6 is highly expressed in the brain and plays a role as the major CYP in the metabolism of numerous brain-penetrant drugs, including antipsychotics and antidepressants. CYP2D6 activity and inhibition have been associated with numerous undesirable effects in patients, such as bioactivation, drug-associated suicidality and prolongation of the QTc interval. Several in silico tools have been developed in recent years to assist safety assessment scientists in predicting the structural identity of CYP2D6-derived metabolites. The first goal of this study was to perform a comparative evaluation on the ability of four commonly used in silico tools (MetaSite, StarDrop, SMARTCyp and RS-WebPredictor) to correctly predict the CYP2D6-derived site of metabolism (SOM) for 141 compounds, including 10 derived from the Genentech small molecule library. The second goal was to evaluate if a bioactivation prediction model, based on an indicator of chemical reactivity (ELUMO–EHOMO) and electrostatic potential, could correctly predict five representative compounds known to be bioactivated by CYP2D6. Such a model would be of great utility in safety assessment since unforeseen toxicities of CYP2D6 substrates may in part be due to bioactivation mechanisms. The third and final goal was to investigate whether molecular docking, using the crystal structure of human CYP2D6, had the potential to compliment or improve the results obtained from the four SOM in silico programs.
Phenolic constituents from Wissadula periplocifolia (L.) C. Presl. and anti-inflammatory activity of 7,4′-di-O-methylisoscutellarein
Creators: name: Teles, Yanna C. F.
name: Ribeiro-Filho, Jaime
name: Bozza, Patrícia T.
name: Agra, Maria De Fátima
name: Weam Siheri
name: Igoli, John O.
name: Gray, Alexander I.
name: Souza, Maria De Fátima V. De
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: This study reports the first phenolics from Wissadula genus (Malvaceae) and the anti-inflammatory activity of 7,4′-di-O-methylisoscutellarein. Using chromatographic methods, five phenolic compounds were isolated from aerial parts of Wissadula periplocifolia (L.) C. Presl. The compounds were identified as 4-hydroxybenzoic acid, 3-hydroxybenzoic acid, trans-cinnamic acid, tamgermanetin and 7,4′-di-O-methylisoscutellarein using spectroscopic methods. The flavone 7,4′-di-O-methylisoscutellarein showed anti-inflammatory activity by inhibiting neutrophils recruitment in a mice model of pleurisy and by decreasing significantly the production of cytokines IL-1β and TNF-α.
A new monoterpene glucoside and complete assignments of dihydroflavonols of Pulicaria jaubertii: potential cytotoxic and blood pressure lowering activity
Creators: name: Ehab A. Ragab
name: Raafat, Mohamed
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Cell Biology
subject: Biochemistry

description: One new monoterpene glucoside and five dihydroflavonols were isolated for the first time from the aerial parts of Pulicaria jaubertii and identified as p-menthane-2-O-β-D-glucopyranoside [1], dihydroquercetin (taxifolin) [2], 7,3′-di-O-methyltaxifolin [3], 3′-O-methyltaxifolin [4], 7-O-methyltaxifolin (padmatin) [5] and 7-O-methyl-dihydrokampferol (7-O-methylaromadenderin) [6]. The structures of these compounds were unambiguously assigned on the basis of NMR spectroscopic data (1H, 13C, DEPT, HSQC, HMBC) and MS analysis. 2D-NMR methods required revision of assignments of H-6 and H-8 for dihydroflavonol compounds. Possible cytotoxic activity as well as blood pressure (BP) lowering activity were tested. The alcoholic extract showed cytotoxic activity against prostate carcinoma (PC-3), breast carcinoma (MCF-7) and hepatocellular carcinoma (HepG-2) human cell lines with IC50 19.1, 20.0 and 24.1 μg, respectively. The higher dose levels of the alcoholic extract significantly reduced normal BP of rats in a dose-dependent manner.
Predicting Early Data Revisions to US GDP and the Effects of Releases on Equity Markets
Creators: name: Clements, Michael P.
name: Ao, Ana Beatriz Galv
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Medicine

description: The effects of data uncertainty on real-time decision-making can be reduced by predicting data revisions to US GDP growth. We show that survey forecasts efficiently predict the revision implicit in the second estimate of GDP growth, but that forecasting models incorporating monthly economic indicators and daily equity returns provide superior forecasts of the data revision implied by the release of the third estimate. We use forecasting models to measure the impact of surprises in GDP announcements on equity markets, and to analyse the effects of anticipated future revisions on announcement-day returns. We show that the publication of better than expected third-release GDP figures provides a boost to equity markets, and if future upward revisions are expected, the effects are enhanced during recessions
Additional file 1 of Megakaryocytic IGF1 coordinates activation and ferroptosis to safeguard hematopoietic stem cell regeneration after radiation injury
Creators: name: Liao, Weinian
name: Chen, Xinliang
name: Zhang, Shuzhen
name: Chen, Jun
name: Liu, Chaonan
name: Yu, Kuan
name: Zhang, Yimin
name: Chen, Mo
name: Chen, Fang
name: Shen, Mingqiang
name: Lu, Binghui
name: Han, Songling
name: Wang, Song
name: Wang, Junping
name: Du, Changhong
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Computational Biology

description: Supplementary Material 1
Thrice better than once: quality control guidelines to validate new mitogenomes
Creators: name: Delsuc, Frédéric
name: Douzery, Emmanuel J. P.
name: Botero-Castro, Fidel
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Genetics

description: Mitogenomic data are increasingly used in evolutionary biology and ecology, stressing the importance for double checking the authenticity of DNA sequences. For example, Szcześniak et al. (2013) recently published the mitochondrial genome of a bat, the Leschenault's rousette (Rousettus leschenaultii). Here we show using straightforward phylogenetic analyses of available chiropteran sequence data that the taxonomic attribution of the reported mitogenome is erroneous. The purportedly-new complete mitochondrial genome likely belongs to the Egyptian fruit bat (R. aegyptiacus) for which a reference sequence already exists. We propose that future articles reporting complete mitochondrial genome sequences should mandatorily include maximum likelihood trees inferred from (i) the standard barcoding marker for the taxon under focus, which would benefit from the massive data available in public databases, and (ii) the available mitogenomes of closely related species. We also strongly advise these trees be presented as phylograms so that all pertinent phylogenetic information is displayed in the form of a topology and its associated branch lengths. Along with compulsory information on the geographical location and origin of the specimen, these new standards should help avoiding the publication of taxonomically misidentified mitogenomes that might end up as reference sequences in public databases and re-used in subsequent meta-analyses.
ASPECTS Dissemination, Exploitation, and Communication Plan
Creators: name: Mitchison, Mark
Publisher: name: Zenodo
Year: 2023

description: This document details the plan for dissemination, exploitation and communication DEC of results for the EU-funded project “Quantum Thermodynamics of Precision in Electronic Devices” (ASPECTS, Grant Agreement No. 101080167). ASPECTS is a fundamental science project, whose main objective is to exploit quantum coherent processes occurring in nanoscale circuit devices to obtain a thermodynamic advantage for precision measurement.

Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Commission. Neither the European Union nor the granting authority can be held responsible for them
Disease activity score in 28 joints at 3 months after the initiation of biologic agent can be a predictive target for switching to the second biologic agent in patients with polyarticular juvenile idiopathic arthritis
Creators: name: Imanaka, Hiroyuki
name: Syuji Takei
name: Kubota, Tomohiro
name: Yamatou, Tsuyoshi
name: Nerome, Yasuhito
name: Yamasaki, Yuuichi
name: Nonaka, Yukiko
name: Akaike, Harumi
name: Takezaki, Tomoko
name: Yosihumi Kawano
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Genetics
subject: Medicine

description: Objective: To clarify polyarticular juvenile idiopathic arthritis (pJIA) patients who failed to maintain prolonged remission with the first biologic agent.Methods: Fourteen pJIA patients were observed for 47.5 months (median) after initiating the first biologic agent.Results: Eight maintained sustained clinical remission (median 47 months) with the first biologic agents, while the six switched to the second one due to lack of efficacy, thereafter. Receiver operating characteristic (ROC) analysis revealed that disease activity score in 28 joints (DAS28) of 2.37 at 3 months could distinguish between the two patient groups (p = 0.001).Conclusion: pJIA patients with DAS28 >2.37 at 3 months of the initial biologic therapy may be considered to switch to the second biologics.
Additional file 1 of Association between risk of preterm birth and long-term and short-term exposure to ambient carbon monoxide during pregnancy in chongqing, China: a study from 2016-2020
Creators: name: Ming, Xin
name: Yang, Yunping
name: Li, Yannan
name: He, Ziyi
name: Tian, Xiaoqin
name: Cheng, Jin
name: Zhou, Wenzheng
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Neuroscience
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Supplementary Material 1
Optimal Eye Surgeon: Finding Image Priors through Sparse Generators at Initialization
Creators: name: Ghosh, Avrajit
name: Zhang, Xitong
name: Sun, Kenneth K.
name: Qu, Qing
name: Ravishankar, Saiprasad
name: Wang, Rongrong
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We introduce Optimal Eye Surgeon (OES), a framework for pruning and training deep image generator networks. Typically, untrained deep convolutional networks, which include image sampling operations, serve as effective image priors (Ulyanov et al., 2018). However, they tend to overfit to noise in image restoration tasks due to being overparameterized. OES addresses this by adaptively pruning networks at random initialization to a level of underparameterization. This process effectively captures low-frequency image components even without training, by just masking. When trained to fit noisy images, these pruned subnetworks, which we term Sparse-DIP, resist overfitting to noise. This benefit arises from underparameterization and the regularization effect of masking, constraining them in the manifold of image priors. We demonstrate that subnetworks pruned through OES surpass other leading pruning methods, such as the Lottery Ticket Hypothesis, which is known to be suboptimal for image recovery tasks (Wu et al., 2023). Our extensive experiments demonstrate the transferability of OES-masks and the characteristics of sparse-subnetworks for image generation. Code is available at https://github.com/Avra98/Optimal-Eye-Surgeon.git.
description: Pruning image generator networks at initialization to alleviate overfitting
An Ordered Lasso and Sparse Time-lagged Regression
Creators: name: Tibshirani, Robert
name: Xiaotong Suo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Medicine

description: We consider regression scenarios where it is natural to impose an order constraint on the coefficients. We propose an order-constrained version of ℓ1-regularized regression (Lasso) for this problem, and show how to solve it efficiently using the well-known Pool Adjacent Violators Algorithm as its proximal operator. The main application of this idea is to time-lagged regression, where we predict an outcome at time t from features at the previous K time points. In this setting it is natural to assume that the coefficients decay as we move farther away from t, and hence the order constraint is reasonable. Potential application areas include financial time series and prediction of dynamic patient outcomes based on clinical measurements. We illustrate this idea on real and simulated data.
A new antifungal labdane diterpene from the leaves of Saraca indica
Creators: name: U. Hawas
name: S. Eltomy
name: R. Nassif
name: G. El-Hossary
name: S. AbouZid
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology
subject: Biochemistry

description: A new labdane diterpene, along with 10 known sterols and flavonoids, was isolated from the hydroalcoholic extract of the leaves of Saraca indica. The chemical structure of the new compound was identified as 6,9-epoxy marrubiinic acid on the basis of spectroscopic analyses including two-dimensional NMR. The antimicrobial potential of the new compound was evaluated against Gram-positive and Gram-negative bacteria as well as fungi. It showed a significant antifungal activity against Geotrichum candidum with MIC 0.48 μg/mL. It also showed potential cytotoxicity against human cancer cell lines with IC50 ranging from 1.07 to 1.29 μg/well.
Chapter 5: Thin-film composite membranes for carbon efficient CO2 electrolysis
Creators: name: Petrov, Kostadin V.
name: Stellema, Teise
name: Vermaas, David A.
Publisher: name: Zenodo
Year: 2024

description: This file contains the datasets relating to Chapter 5 of the thesis "Addressing CO2 electrolysis challenges with novel ion-exchange membranes" by Kostadin V. Petrov.

The data is in .opju format, used by the Origin Pro software to create the associated figures.
How Limiting Factors Drive Agricultural Adaptation to Climate Change
Creators: name: Niles, Meredith
name: Lubell, Mark
name: Brown, Margaret
Publisher: name: figshare
Year: 2015
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Applied Psychology
subject: Climate Science

description: Consensus is growing that agriculture is vulnerable to climate change and adaptation responses are necessary to minimize impacts. Nonetheless, the diversity of potential impacts, agro-ecological contexts and regional capacity for change make understanding adaptation behaviors challenging and ensure that climate change adaptation will not be the same across all contexts. Considering this heterogeneity, this paper aims to develop a theoretical approach to connect agro-ecosystem diversity with farmer decision-making in the context of agricultural adaptation to climate change. We combine the ecological principle of Liebig’s Law of the Minimum with the Psychological Distance Theory to suggest how adaptation behaviors vary across regional contexts. We argue with our limiting factors hypothesis that limiting factors within a farm system (water or temperature impacts) influence the adoption of adaptation practices differently across regions and farm systems. Limiting factors varied across farm systems and regions, based on historical climate changes, agro-ecological contexts, infrastructure and adaptation capacity. Using farmer survey data from New Zealand we show that limiting factors mediate the effect of past climate experiences on the adoption of adaptation strategies differently in two regions with water acting as a limiting factor in Hawke’s Bay and water and temperature as a limiting factor in Marlborough. This suggests that farmers perceive and respond to climate change in part due to their personal experiences with climate change and the limiting factors within their system. Such results are relevant for the development of regional adaptation strategies, effective policies and targeted climate change communication.
Global and Local Concerns: What Attitudes and Beliefs Motivate Farmers to Mitigate and Adapt to Climate Change?
Creators: name: Niles, Meredith
name: Haden, Van Ryan
name: Lubell, Mark
name: Perlman, Joshua
name: Jackson, Louise
Publisher: name: figshare
Year: 2015
Subjects: Personality, Social and Criminal Psychology
Climate Science

description: In response to agriculture's vulnerability and contribution to climate change, many governments are developing initiatives that promote the adoption of mitigation and adaptation practices among farmers. Since most climate policies affecting agriculture rely on voluntary efforts by individual farmers, success requires a sound understanding of the factors that motivate farmers to change practices. Recent evidence suggests that past experience with the effects of climate change and the psychological distance associated with people's concern for global and local impacts can influence environmental behavior. Here we surveyed farmers in a representative rural county in California's Central Valley to examine how their intention to adopt mitigation and adaptation practices is influenced by previous climate experiences and their global and local concerns about climate change. Perceived changes in water availability had significant effects on farmers' intention to adopt mitigation and adaptation strategies, which were mediated through global and local concerns respectively. This suggests that mitigation is largely motivated by psychologically distant concerns and beliefs about climate change, while adaptation is driven by psychologically proximate concerns for local impacts. This match between attitudes and behaviors according to the psychological distance at which they are cognitively construed indicates that policy and outreach initiatives may benefit by framing climate impacts and behavioral goals concordantly; either in a global context for mitigation or a local context for adaptation.
Additional file 1 of How well do participants in clinical trials represent the U.S. population with chronic neck or back pain?
Creators: name: Leininger, Brent D.
name: Johnson, Pamela Jo
name: Bronfort, Gert
name: Kuntz, Karen M.
name: Enns, Eva
name: Hodges, James S.
name: Evans, Roni
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Science Policy

description: Supplementary Material 1
Chaotic magnetization dynamics driven by feedback magnetic field
Creators: name: Taniguchi, Tomohiro
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: An excitation of highly nonlinear, complex magnetization dynamics in a ferromagnet, for example chaos, is a new research target in spintronics. This technology is applied to practical applications such as random number generator and information processing systems. One way to induce complex dynamics is applying feedback effect to the ferromagnet. The role of the feedback electric current on the magnetization dynamics was studied in the past. However, there is another way to apply feedback effect to the ferromagnet, namely feedback magnetic field. In this paper, we developed both numerical and theoretical analyses on the role of the feedback magnetic field causing complex magnetization dynamics. The numerical simulation indicates the change of the dynamical behavior from a simple oscillation with a unique frequency to complex dynamics such as amplitude modulation and chaos. The theoretical analyses on the equation of motion qualitatively explain several features found in the numerical simulations, exemplified as an appearance of multipeak structure in the Fourier spectra. The difference of the role of the feedback electric current and magnetic field is also revealed from the theoretical analyses.
description: 9 pages, 5 figures
Evaluating the Impact of Retaliatory Tariffs on U.S. Soybeans in China
Creators: name: Muhammad, Andrew
name: Smith, S. Aaron
name: Muhammad, Andrew
name: Smith, S. Aaron
Publisher: name: Unknown
Year: 2018
Subjects: subject: Agricultural and Food Policy
subject: Financial Economics
subject: International Relations/Trade
subject: evaluating
subject: impact
subject: retaliatory
subject: tariffs
subject: U.S.
subject: soybeans
subject: China
subject: intellectual
subject: property
subject: trade
subject: practices

description: On March 8, 2018, President Donald Trump signed proclamations to impose tariffs on steel and aluminum imports. The proclamations were based on a Department of Commerce report that indicated that the current level of aluminum and steel imports have the potential to threaten U.S. national security (White House, Office of the Press Secretary, 2018a; 2018b). On March 22, 2018, President Donald Trump also signed a memorandum to impose tariffs on Chinese goods of $50 billion, which was based on an investigation by the Office of the U.S. Trade Representative on China’s laws, policies and practices related to intellectual property rights, innovation and technology transfer (White House, Presidential Memorandum, 2018). The proposed steel and aluminum tariffs are based on Section 232 of the Trade Expansion Act of 1962 (White House, Office of the Press Secretary, 2018a). The proposed $50 billion in tariffs on Chinese goods are based on Section 301 of the Trade Act of 1974, which gives the U.S. broad authority to respond to unfair trade practices (Leonard, 2018). Accordingly, the proposed tariffs are often referred to as 232 and 301 tariffs (we use this terminology in the report). The Chinese government responded to the 232 and 301 tariffs by threatening its own tariffs on U.S. goods, including soybeans (Caporal, 2018). Although, as of April 16, 2018, nothing has been implemented, concerns have been raised by the U.S. soybean industry about potential negative impacts (Huffstutter, 2018). If the Chinese government retaliates by imposing tariffs on U.S. soybeans, how could this impact U.S. soybean exports? In recent years, Brazil has significantly increased soybean exports to China. Could retaliatory tariffs against the U.S. result in gains for Brazil? Based on ongoing research of China’s soybean import market, we present findings of how retaliatory tariffs could impact U.S. and Brazilian soybean exports to China. This issue is particularly important because the U.S. soybean sector is very dependent on global markets, with China being the primary destination.
Tax Amnesties as an Aid to Peace Deals and Political Settlements
Creators: name: Institute for Integrated Transitions
Publisher: name: Zenodo
Year: 2020
Subjects: taxes
tax amnesty
tax amnesties
political settlements
peace deals
IFIT
legal measure
justice
illicit assets
prosecution
penalty
sanctions
economic crimes
negotiations
application window
tax evasion
enforcement mechanisms
agreements
exchange of information
mutual legal assistance treaties
MLA treaties
anti-money laundering obligations
Financial Action Task Force

description: This paper is authored in principal by Mark Freeman / IFIT Executive Director, Rob Dedman and Lisa McKinnon-Lower.

 

This IFIT discussion paper is part of a larger project on the negotiation and treatment of economic crimes as part of a comprehensive conflict prevention and resolution strategy.

Political amnesty for atrocity crimes is a common expectation in negotiations with warlords, dictators, military commanders, paramilitary chiefs, rebel leaders and others, because it offers desirable legal security at the national level. Yet, political amnesty only goes so far. It does not provide the legal protection these figures often want for illicit assets or businesses they may control. As such, the prospect of a negotiated peace deal or political transition risks exposing themselves to personal disgrace, wealth destruction, jail time and an adverse impact on the lives of family members.

With such considerations in mind, this IFIT discussion paper explores the novel prospect of applying techniques and lessons derived from the global use of conditional tax amnesties to the context and end-goals of a peace negotiation. It examines the basic concept of tax amnesties and relevant trends and data from their global use, before proposing ways to apply tax amnesty techniques that might generate better conditions for inducing, reaching, and implementing negotiated peace deals and political settlements.
[Bibliography] Coronaviruses • SARS • MERS • COVID-19
Creators: name: Pfister, Rodo
Publisher: name: Zenodo
Year: 2020
Subjects: SARS
MERS
COVID-19
Coronaviruses

description: Contents Coronaviruses in general. 3 SARS-Cov • Severe Acute Respiratory Syndrome coronavirus. 6 Traditional Chinese medicine. 11 MERS-CoV • Middle East Respiratory Syndrome coronavirus. 21 SARSr-CoV • Severe acute respiratory syndrome-related coronaviruses. 23 COVID-19 • SARS-CoV-2 • 2019-nCoV. 31 Case reporting websites. 31 Daily reports WHO • NHC PRC • Health Commission of Hubei Province. 34 Bibliographies • Living Papers. 34 Syllabi • Teaching Tools. 34 COVID-19 Research & Development. 35 Biomedical, epidemiological, genetic studies. 36 Websites collecting scientific information.. 36 Virology • Phylogeny and Genome of SARS-like betacoronaviruses. 38 Epidemiology • Transmission • Modelling • Testing. 65 Clinical disease • pathology • pathophysiology. 82 Treatment options • vaccines. 92 Retractions • Withdrawals. 98 Guidelines • Guidance for COVID-19. 100 Traditional Chinese medicine. 102 Press reports. 108 Updating thematic lists of news outlets. 108 News articles. 109 Sociocultural reactions • arts • social sciences • social anthropology. 129 Pandemic memes. 136 Rumours • disinformation • propaganda war. 139 Anti-racist stance.. 139 Notification on false information.. 139 Discussion of propaganda articles • Infodemic • Desinformation.. 140 Enfer • Propaganda articles. 143
Coming out of your shell or crawling back in: Multiple interphylum host switching events within a clade of bivalve- and ascidian-associated shrimps (Caridea: Palaemonidae)
Creators: name: Gier, Werner de
name: Groenhof, Mike
name: Fransen, Charles H.J.M.
Publisher: name: Brill Online
Year: 2022
Subjects: Evolutionary biology not elsewhere classified

description: Marine symbiotic Palaemonidae, comprising over 600 species, live in association with marine invertebrates of different phyla, like Cnidaria, Echinodermata, Mollusca, Porifera, and Tunicata. A phylogenetic study is performed on a clade of bivalve- and ascidian-associated endosymbiotic shrimp species (Caridea: Palaemonidae), using morphological and molecular data. A Total Evidence approach is used in order to include all known species in an evolutionary framework. Ancestral state reconstruction analyses are performed to identify host-switching events and ancestral ranges. The clade, including Ascidonia, Conchodytes, Dactylonia, Odontonia, and Pontonia, and various smaller genera, is recovered as monophyletic, with an ascidian-associated ancestral host state. At least six interphylum host switches are tentatively identified, with members of Odontonia and Notopontonia switching back to an ascidian host affiliation after the ancestral host switch of the clade including Conchodytes, Odontonia and related genera, from an ascidian- to a bivalve host. The clade including Ascidonia and Pontonia was recovered to have an ancestor with an East Pacific/Atlantic distribution. The other studied genera remained in the original ancestral Indo-West Pacific range. We hypothesize that similar internal environments of shrimp hosts from different phyla will function as hot spots for interphylum host switching in various lineages of symbionts.
BOʻLAJAK FIZIKA OʻQITUVCHILARINING KASBIY KOMPETENTLIGINI RIVOJLANTIRISH USULLARI VA MEZONLARI
Creators: name: Aminov, Alijon
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolada bo'lajak fizika o'qituvchilarining kasbiy kompetentligini rivojlanishiga hissa qo'shadigan muhim pedagogik va didaktik sharoitlari, usullari va kasbiy kompetenti mezonlari haqida soʻz yuritiladi.
An Analytical Research on Face Recognition  Attendance System for Employees using Machine  Learning
Creators: name: Afaque Alam
Publisher: name: Zenodo
Year: 2020

description: The primary goal of this paper is to develop a facial recognition-based attendance monitoring system for educational institutions in order to improve and modernise the existing system and make it more effective and efficient than it was in the past. Numerous ambiguities in the previous, outdated approach led to imprecise and ineffective attendance recording. When the authority is unable to enforce the regulations that were in place under the previous system, several issues occur. The facial recognition system will be the technology underlying this. One of the natural characteristics that may be used to identify a person specifically is their face. Since there is little chance of a face deviating or being replicated, it is utilised to trace identification. Face databases will be developed in this study in order to provide information into the recognizer algorithm. Then, in order to determine identification, faces will be compared to the database during the attendance-taking session. Upon identification, the attendance of that person will be automatically recorded, with the relevant data being stored in an Excel spreadsheet.
How Is the Margin Protection Program Performing for Tennessee Dairy Producers?
Creators: name: Griffith, Andrew P.
name: Bilderback, David
name: Eckelkamp, Liz
name: Griffith, Andrew P.
name: Bilderback, David
name: Eckelkamp, Liz
Publisher: name: Unknown
Year: 2018
Subjects: subject: Agricultural and Food Policy
subject: Farm Management
subject: Livestock Production/Industries
subject: Risk and Uncertainty
subject: margin
subject: protection
subject: program
subject: performing
subject: Tennessee
subject: dairy
subject: producers
subject: agricultural
subject: act
subject: farm
subject: bill

description: The Margin Protection Program (MPP) for dairy producers was established by the Agricultural Act of 2014 (2014 Farm Bill) to reduce the market risk of dairy producers associated with the all-milk price and average feed costs. However, the MPP was amended in 2018. This article: 1. Summarizes key changes to the MPP program as a result of the 2018 amendments; 2. Summarizes the technical performance of the program, as originally established in the 2014 Farm Bill; 3. Summarizes, retrospectively, the technical performance of the program, as amended by the Bipartisan Budget Act of 2018; and 4. Summarizes feedback on the MPP provided to the authors by Tennessee dairy producers.
Additional file 1 of Validation of the eating pathology symptoms inventory (EPSI) in Swedish adolescents
Creators: name: Birgegård, Andreas
name: Isomaa, Rasmus
name: Monell, Elin
name: Bjureberg, Johan
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Supplementary Material 1