cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks.
Creators: name: Jarvela, Alys M. Cheatle
name: Brubaker, Lisa
name: Vedenko, Anastasia
name: Anisha  Gupta
name: Armitage, Bruce
name: Bulyk, Martha L.
name: Hinman, Veronica F.
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Gene regulatory networks (GRNs) describe the progression of transcriptional states that take a single-celled zygote to a multicellular organism. It is well documented that GRNs can evolve extensively through mutations to cis-regulatory modules (CRMs). Transcription factor proteins that bind these CRMs may also evolve to produce novelty. Coding changes are considered to be rarer, however, because transcription factors are multifunctional and hence are more constrained to evolve in ways that will not produce widespread detrimental effects. Recent technological advances have unearthed a surprising variation in DNA-binding abilities, such that individual transcription factors may recognize both a preferred primary motif and an additional secondary motif. This provides a source of modularity in function. Here, we demonstrate that orthologous transcription factors can also evolve a changed preference for a secondary binding motif, thereby offering an unexplored mechanism for GRN evolution. Using protein-binding microarray, surface plasmon resonance, and in vivo reporter assays, we demonstrate an important difference in DNA-binding preference between Tbrain protein orthologs in two species of echinoderms, the sea star, Patiria miniata, and the sea urchin, Strongylocentrotus purpuratus. Although both orthologs recognize the same primary motif, only the sea star Tbr also has a secondary binding motif. Our in vivo assays demonstrate that this difference may allow for greater evolutionary change in timing of regulatory control. This uncovers a layer of transcription factor binding divergence that could exist for many pairs of orthologs. We hypothesize that this divergence provides modularity that allows orthologous transcription factors to evolve novel roles in GRNs through modification of binding to secondary sites.
Geometry of wave propagation on active deformable surfaces
Creators: name: Miller, Pearson W.
name: Stoop, Norbert
name: Dunkel, Jörn
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Fundamental biological and biomimetic processes, from tissue morphogenesis to soft robotics, rely on the propagation of chemical and mechanical surface waves to signal and coordinate active force generation. The complex interplay between surface geometry and contraction wave dynamics remains poorly understood, but will be essential for the future design of chemically-driven soft robots and active materials. Here, we couple prototypical chemical wave and reaction-diffusion models to non-Euclidean shell mechanics to identify and characterize generic features of chemo-mechanical wave propagation on active deformable surfaces. Our theoretical framework is validated against recent data from contractile wave measurements on ascidian and starfish oocytes, producing good quantitative agreement in both cases. The theory is then applied to illustrate how geometry and preexisting discrete symmetries can be utilized to focus active elastic surface waves. We highlight the practical potential of chemo-mechanical coupling by demonstrating spontaneous wave-induced locomotion of elastic shells of various geometries. Altogether, our results show how geometry, elasticity and chemical signaling can be harnessed to construct dynamically adaptable, autonomously moving mechanical surface wave guides.
description: text changes abstract and intro, new results on self-propelled elastic shells added; 5 pages, 3 figures; videos available on request
title: Transcriptions du Y//3 - Livre rouge , page #056
Creators: name: Brochard, Pierre
name: Claustre, Julie
name: Regazzi, Hugo
name: Claustre, Julie
name: Brochard, Pierre
name: Regazzi, Hugo
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: Laboratoire de médiévistique occidentale de Paris
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Châtelet de Paris
subject: http://www.idref.fr/032506511/id

description: Transcriptions de certaines pages du Y//3 - Livre Rouge, Châtelet de Paris, Y//1-Y//6/6. Livres de couleur (1223-1604)
Les images liées sont indiquées par le champ Source.

Les transcriptions sont dans deux formats : Txt et PageXml.

Liste des abréviations

App(b)eillees = appareillées
Bouch'r = boucher
Com'e = comme
Laut' = l'autre
Daut' = d'autre
Par' = Paris
Com'andem's = commandemens
Cestass' = c'est assavoir
Envir' = environ
App(b)tient = appartient
Ass' = assavoir
Ch'un = chascun
Oucas = ou cas
Enioint = enjoint
T'spas = trespas
Entiere = entière
Aleurs = à leurs

Les apostrophes représentent les tildes et '(b)' signifie que le jambage de la lettre précédente est barré.
description: Source: https://www.siv.archives-nationales.culture.gouv.fr/siv/media/FRAN_IR_056373/c-2xp1c58jd-1w19uv1g8sus6/FRAN_0053_01056_L
description: Source: https://www.nakala.fr/10.34847/nkl.55cdsz68
description: Relation: https://lamop.hypotheses.org/
description: Bibliographic citation: Hugo Regazzi, Pierre Brochard, Julie Claustre - Transcriptions du Y//3 - Livre Rouge du Châtelet de Paris, page #01056
description: Transcriptions du Y//3 - Livre Rouge page #056 - Format Text
description: Transcriptions du Y//3 - Livre Rouge page #056 - Format PageXML
Buglossoides purpurocaerulea I. M. Johnst.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Boraginales
Boraginaceae
Buglossoides
Buglossoides purpurocaerulea

description: Lithospermum purpurocaeruleum Linnaeus, Species Plantarum 1: 132. 1753.
"Habitat in Ungariae, Angliae, Galliae nemoribus." RCN: 1072.
 Lectotype (Selvi in Cafferty & Jarvis in Taxon 53: 802. 2004): Herb. Linn. No. 181.8 (LINN).
 Current name: Buglossoides purpurocaerulea (L.) I.M. Johnst. (Boraginaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 637, DOI: 10.5281/zenodo.291971
Superfield Realizations of Lorentz Violation
Creators: name: Berger, M. S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Lorentz-violating extensions of the Wess-Zumino model have been formulated in superspace. The models respect a supersymmetry algebra and can be understood as arising from suitably modified superspace transformations.
description: 7 pages
Iterative inversion of synthetic travel times successful at recovering sub-surface profiles of supergranular flows
Creators: name: Bhattacharya, Jishnu
name: Hanasoge, Shravan M.
name: Birch, Aaron C.
name: Gizon, Laurent
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We develop a helioseismic inversion algorithm that can be used to recover sub-surface vertical profiles of 2-dimensional supergranular flows from surface measurements of synthetic wave travel times. We carry out seismic wave-propagation simulations through a 2-dimensional section of a flow profile that resembles an averaged supergranule, and a starting model that has flows only at the surface. We assume that the wave measurements are entirely without realization noise for the purpose of our test. We expand the vertical profile of the supergranule stream function on a basis of B-splines. We iteratively update the B-spline coefficients of the supergranule model to reduce the travel-times differences observed between the two simulations. We carry out the exercise for four different vertical profiles peaking at different depths below the solar surface. We are able to accurately recover depth profiles of four supergranule models at depths up to $8-10\,\text{Mm}$ below the solar surface using $f-p_4$ modes, under the assumption that there is no realization noise. We are able to obtain the peak depth and the depth of the return flow for each model. A basis-resolved inversion performs significantly better than one where the flow field is inverted for at each point in the radial grid. This is an encouraging result and might act as a guide in developing more realistic inversion strategies that can be applied to supergranular flows in the Sun.
description: Accepted for publication in in A&A, 11 pages, 6 figures
Radio emission from shell-type supernova remnants
Creators: name: Asvarov, Abdul
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The evolution of the radio emission of shell-type Supernova remnants (SNRs) is modeled within the framework of the simple and commonly used assumptions that the mechanism of diffusive shock acceleration (DSA) is responsible for generating radio emitting electrons and that the magnetic field is the typical interstellar field compressed at the shock. It is considered that electrons are injected into the mechanism in test-particle regime directly from the high energy tail of the downstream Maxwellian distribution function. The model can be applied to most of the observed SNRs. It is shown that the model successfully explains the many averaged observational properties of evolved shell-type SNRs. In particular, the radio surface brightness ($Σ$) evolves with diameter as $\sim D^{-(0.3 ÷0.5)}$, while the bounding shock is strong (Mach number is ${\mathcal M} \geq10$), followed by steep decrease (steeper than $\sim D^{-4.5}$) for ${\cal M} <10$. Such evolution of the surface brightness with diameter and its strong dependence on the environmental parameters strongly reduce the usefulness of $Σ- D$ relations as a tool for determining the distances to SNRs. The model predicts no radio emission from SNRs in the late radiative stage of evolution and the existence of radio-quiet but relatively active SNRs is possible. Our model easily explains very large-diameter radio sources such as the Galactic Loops and the candidates for Hypernova radio remnants. The model predicts that most of the observed SNRs are located in a tenuous phase of the ISM. From the comparison of the model results with the statistics of evolved shell-type SNRs, we were able to estimate the fraction of electrons accelerated from the thermal pool in the range $(3÷11) \times 10^{- 4}$.
description: 17 pages, 7 figures, Accepted for publication in Astronomy & Astrophysics
title: ADCO, Cartulaire des Dominicains de Dijon (1286), Cart. 221 (H 53), 170 folios, f. 0053
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire des Dominicains de Dijon (1286), Archives départementales de la Côte-d'Or, Cart. 221 (H 53), 170 folios. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire des Dominicains de Dijon (1286), Archives départementales de la Côte-d'Or, Cart. 221 (H 53), 170 folios, f. 0053, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb15250518p
description: Provenance: http://www.idref.fr/02643413X/id
description: Provenance: https://www.geonames.org/6453767
description: Provenance: Dijon
description: Provenance: http://www.wikidata.org/entity/Q7003
Sepsis-trained macrophages promote anti-tumoral tissue-resident T cell.
Creators: name: GOURAIN, victor
Publisher: name: Zenodo
Year: 2024

description: Bioinformatics methods for scientific publication in Nature Immunology titled:

Sepsis-trained macrophages promote anti-tumoral tissue-resident T cell

authored by Broquet, Gourain, Goronflot et al., in 2024
Mod-seq: high-throughput sequencing for chemical probing of RNA structure.
Creators: name: Talkish, Jason
name: May, Gemma
name: Yizhu  Lin
name: Woolford, John
name: C. Joel McManus
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The functions of RNA molecules are intimately linked to their ability to fold into complex secondary and tertiary structures. Thus, understanding how these molecules fold is essential to determining how they function. Current methods for investigating RNA structure often use small molecules, enzymes, or ions that cleave or modify the RNA in a solvent-accessible manner. While these methods have been invaluable to understanding RNA structure, they can be fairly labor intensive and often focus on short regions of single RNAs. Here we present a new method (Mod-seq) and data analysis pipeline (Mod-seeker) for assaying the structure of RNAs by high-throughput sequencing. This technique can be utilized both in vivo and in vitro, with any small molecule that modifies RNA and consequently impedes reverse transcriptase. As proof-of-principle, we used dimethyl sulfate (DMS) to probe the in vivo structure of total cellular RNAs in Saccharomyces cerevisiae. Mod-seq analysis simultaneously revealed secondary structural information for all four ribosomal RNAs and 32 additional noncoding RNAs. We further show that Mod-seq can be used to detect structural changes in 5.8S and 25S rRNAs in the absence of ribosomal protein L26, correctly identifying its binding site on the ribosome. While this method is applicable to RNAs of any length, its high-throughput nature makes Mod-seq ideal for studying long RNAs and complex RNA mixtures.
Alkanna matthioli Tausch 1824
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Boraginales
Boraginaceae
Alkanna
Alkanna matthioli

description: Lithospermum tinctorium Linnaeus, Species Plantarum 1: 132. 1753.
"Habitat in Oriente, Monspelii." RCN: 1078.
 Basionym of: Anchusa tinctoria (L.) L. (1762).
 Lectotype (Selvi & al. in Cafferty & Jarvis in Taxon 53: 802. 2004): [icon] " Anchusa monspeliana" in Bauhin & Cherler, Hist. Pl. Univ. 3(2): 584. 1651. - Epitype (Selvi in Cafferty & Jarvis in Taxon 53: 802. 2004): France. Montpellier, May 1861, G. Watson-Taylor 465 (FI).
 Current name:  Alkanna matthioli Tausch  (Boraginaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 637, DOI: 10.5281/zenodo.291971
DNN Transfer Learning based Non-linear Feature Extraction for Acoustic Event Classification
Creators: name: Mun, Seongkyu
name: Shin, Minkyu
name: Shon, Suwon
name: Kim, Wooil
name: Han, David K.
name: Ko, Hanseok
Publisher: name: arXiv
Year: 2017
Subjects: subject: Sound (cs.SD)
subject: FOS: Computer and information sciences

description: Recent acoustic event classification research has focused on training suitable filters to represent acoustic events. However, due to limited availability of target event databases and linearity of conventional filters, there is still room for improving performance. By exploiting the non-linear modeling of deep neural networks (DNNs) and their ability to learn beyond pre-trained environments, this letter proposes a DNN-based feature extraction scheme for the classification of acoustic events. The effectiveness and robustness to noise of the proposed method are demonstrated using a database of indoor surveillance environments.
Pre-Analysis Plan: A Meta-Analysis on Intergenerational Income Mobility
Creators: name: Bom, Pedro R. D.
name: Stojanovikj, Martin
name: Rachinger, Heiko
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Economics
subject: Social and Behavioral Sciences
subject: intergenerational income elasticity
subject: intergenerational income mobility
subject: meta-analysis

description: We register a pre-analysis plan for a meta-analysis on intergenerational income mobility. Intergenerational mobility refers to the changes in social status that occur from one generation to the next within a society. Our meta-analysis focuses on the intergenerational transmission of income.

Typically, primary studies use individual-level data to model the child's (log) income in relation to the parent's (log) income. The slope coefficient in this regression represents the intergenerational income elasticity, which quantifies the extent to which a parent's income influences their child's income. A higher value of this parameter indicates lower intergenerational income mobility. Researchers have explored various modifications to this basic framework, such as considering different income averaging periods, measuring income at different ages, and introducing different control variables. These methodological differences naturally lead to significant variation in empirical results across studies.

The objective of our study is to synthesize this literature using meta-analysis techniques. We aim to obtain precise estimates of intergenerational income elasticity for different countries and to uncover the study design factors that contribute to the variation in results in the literature, while correcting for the possible presence of publication bias. We are especially interested in testing some hypotheses that have been raised in the literature concerning possible sources of bias, namely the so-called life-cycle bias and age-related measurement error bias. We also plan to examine the so-called 'Great Gatsby' curve, which relates intergenerational mobility with income inequality.
Modification of globin gene expression by RNA targeting strategies.
Creators: name: Tong-Jian  Shen
name: Rogers, Heather
name: Xiaobing  Yu
name: Lin, Felix
name: Noguchi, Constance T.
name: Ho, Chien
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: OBJECTIVE: Sickle cell anemia is a genetic blood disease resulting from production of mutant beta-globin (beta(S)) and has severe clinical consequences. It is known that a higher cellular gamma-globin level, e.g., higher ratio of cellular gamma-globin to beta(S)-globin (gamma/beta(S) ratio), inhibits sickle hemoglobin (HbS) polymerization tendency. Hence, therapeutic treatment of sickle cell anemia has been focused on introducing gamma-globin gene into red blood cells to increase the cellular gamma/beta(S) ratio. Here, we have introduced ribozymes and small interfering RNAs (siRNAs) against beta(S)-globin mRNA into blood cells as a means to increase the gamma/beta(S) ratio. MATERIALS AND METHODS: Single and multiribozymes against beta(S)-globin mRNA have been tested in vitro and in human erythroleukemia K562beta(S) cells that stably express exogenous beta(S)-globin gene. Primary human hematopoietic progenitor cells were also transfected with multiribozyme and the gamma/(gamma + beta) ratio determined and compared with cells transfected with long hairpin beta-globin cDNA and synthetic siRNA genes. RESULTS: We have found that the multiribozyme zb21A containing two ribozyme units effectively reduces beta(S)-globin mRNA both in vitro and in K562beta(S) cells. The gamma-globin mRNA to beta(S)-globin mRNA ratio in the multiribozyme transfected cells is about a factor of 2 more than that in the control cells. We have also found that the gamma/(gamma + beta) ratio in the transfected hematopoietic progenitor cells is increased by more than twofold in cells treated with multiribozyme zb21A or siRNA ib5. CONCLUSION: Our results suggest that introducing multiribozymes or siRNAs into red blood cells is comparable in their effectiveness to increase the ratio of cellular gamma-globin mRNA to beta- or beta(S)-globin mRNA, providing possible strategies to increase the effectiveness of gamma-globin gene transfer as gene therapy for treatment of patients with sickle cell anemia.
Flavor Structure of Scherk-Schwarz Supersymmetry Breaking for Quasi-Localized Matter Field
Creators: name: Choi, Kiwoon
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We discuss the flavor structure of soft supersymmetry breaking parameters in 5-dimensional orbifold field theories in which N=1 supersymmetry is broken by the Scherk-Schwarz boundary condition and hierarchical 4-dimensional Yukawa couplings are obtained by quasi-localizing the matter fields in extra dimension. In such theories, the resulting soft scalar masses and trilinear scalar couplings at the compactification scale are highly flavor-dependent, but appropriately suppressed in correlation with Yukawa couplings. Those flavor violations can give interesting phenomenological consequences at low energies as well as constrain the mechanism of Yukawa coupling generation.
description: 5 pages, Revtex4, Talk presented at 2nd International Conference on Flavor Physics (ICFP 2003), KIAS, Seoul, Korea, Oct.6-11, 2003. To appear in the proceeding
Response to 'Burden of proof: A comprehensive review of the feasibility of 100% renewable-electricity systems'
Creators: name: Brown, T. W.
name: Bischof-Niemz, T.
name: Blok, K.
name: Breyer, C.
name: Lund, H.
name: Mathiesen, B. V.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: A recent article 'Burden of proof: A comprehensive review of the feasibility of 100% renewable-electricity systems' claims that many studies of 100% renewable electricity systems do not demonstrate sufficient technical feasibility, according to the criteria of the article's authors (henceforth 'the authors'). Here we analyse the authors' methodology and find it problematic. The feasibility criteria chosen by the authors are important, but are also easily addressed at low economic cost, while not affecting the main conclusions of the reviewed studies and certainly not affecting their technical feasibility. A more thorough review reveals that all of the issues have already been addressed in the engineering and modelling literature. Nuclear power, which the authors have evaluated positively elsewhere, faces other, genuine feasibility problems, such as the finiteness of uranium resources and a reliance on unproven technologies in the medium- to long-term. Energy systems based on renewables, on the other hand, are not only feasible, but already economically viable and decreasing in cost every year.
description: 11+7 pages, 2 figures; version 2 contains clarifications and further references; version 3 is the accepted manuscript
Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications
Creators: name: Singh, Harpreet
name: Chopra, Hitesh
name: Singh, Inderbir
name: Mohanto, Sourav
name: Ahmed, Mohammed Gulzar
name: Ghumra, Shruti
name: Seelan, Anmol
name: Survase, Manisha
name: Kumar, Arvind
name: Mishra, Amrita
name: Mishra, Arun Kumar
name: Kamal, Mohammad Amjad
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2024
Subjects: skin cancer
clinical trials
combination strategies
clinical implications
patient

description: Cutaneous Squamous Cell Carcinoma (cSCC) is a common and potentially fatal type of skin cancer that poses a significant threat to public health and has a high prevalence rate. Exposure to ultraviolet radiation on the skin surface increases the risk of cSCC, especially in those with genetic syndromes like xerodermapigmentosum and epidermolysis bullosa. Therefore, understanding the molecular pathogenesis of cSCC is critical for developing personalized treatment approaches that are effective in cSCC. This article provides a comprehensive overview of current knowledge of cSCC pathogenesis, emphasizing dysregulated signaling pathways and the significance of molecular profiling. Several limitations and challenges associated with conventional therapies, however, are identified, stressing the need for novel therapeutic strategies. The article further discusses molecular targets and therapeutic approaches, i.e., epidermal growth factor receptor inhibitors, hedgehog pathway inhibitors, and PI3K/AKT/mTOR pathway inhibitors, as well as emerging molecular targets and therapeutic agents. The manuscript explores resistance mechanisms to molecularly targeted therapies and proposes methods to overcome them, including combination strategies, rational design, and optimization. The clinical implications and patient outcomes of molecular-targeted treatments are assessed, including response rates and survival outcomes. The management of adverse events and toxicities in molecular-targeted therapies is crucial and requires careful monitoring and control. The paper further discusses future directions for therapeutic advancement and research in this area, as well as the difficulties and constraints associated with conventional therapies.
description: EXCLI Journal; 23:Doc300; ISSN 1611-2156
Onosmodium virginianum
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Boraginales
Boraginaceae
Onosmodium
Onosmodium virginianum

description: Lithospermum virginianum Linnaeus, Species Plantarum 1: 132. 1753.
"Habitat in Virginia." RCN: 1070.
 Lectotype (Wells in Cafferty & Jarvis in Taxon 53: 802. 2004): Clayton 647 (BM-000051717).
 Current name: Onosmodium virginianum (L.) A. DC. (Boraginaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 637, DOI: 10.5281/zenodo.291971
Stability of relative equilibria with singular momentum values in simple mechanical systems
Creators: name: Rodriguez-Olmos, Miguel
Publisher: name: arXiv
Year: 2005
Subjects: subject: Dynamical Systems (math.DS)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 37J25; 77H33; 53D20

description: A method for testing $G_μ$-stability of relative equilibria in Hamiltonian systems of the form "kinetic + potential energy" is presented. This method extends the Reduced Energy-Momentum Method of Simo et al. to the case of non-free group actions and singular momentum values. A normal form for the symplectic matrix at a relative equilibrium is also obtained.
description: Partially rewritten. Some mistakes fixed. Exposition improved
Electron conduction in solid state via time varying wavevectors
Creators: name: Khaneja, Navin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: In this paper, we study electron wavepacket dynamics in electric and magnetic fields. We rigorously derive the semiclassical equations of electron dynamics in electric and magnetic fields. We do it both for free electron and electron in a periodic potential. We do this by introducing time varying wavevectors $k(t)$. In the presence of magnetic field, our wavepacket reproduces the classical cyclotron orbits once the origin of the Schröedinger equation is correctly chosen to be center of cyclotron orbit. In the presence of both electric and magnetic fields, our equations for wavepacket dynamics differ from classical Lorentz force equations. We show that in a periodic potential, on application of electric field, the electron wave function adiabatically follows the wavefunction of a time varying Bloch wavevector $k(t)$, with its energies suitably shifted with time. We derive the effective mass equation and discuss conduction in conductors and insulators.
description: 15 pages, 6 figures
title: Detection and diagnosis of acute viral encephalitis
Creators: name: Michael, Benedict
Publisher: name: University of Liverpool Repository
Year: 2020

description: Introduction Acute viral encephalitis is a severe form of brain inflammation due to sporadic infection, typically with herpes simplex virus, or epidemic/pandemic infections. Epidemiological data are particularly important for pandemic viruses. Although new reporting approaches are often considered, no real-time clinical data collection tool has been developed. These data are dependent on diagnosis of individual cases. However, the aspects of management that result in delays and missed diagnoses are not clear and it is not known if interventions can improve sample collection and diagnosis. Whilst the importance of cytokines and associated mediators is increasingly recognised, signatures associated with specific aetiologies have not been established. Also, it is not known whether these mediators correlate with clinical severity and outcome, or their impact on blood-brain barrier permeability. Methods I undertook a national surveillance study through neurology networks, and investigated alternative notification approaches. I undertook a multicentre cross-sectional study of clinical investigation, studied viral load and assessed the impact of a lumbar puncture pack. I used bead array to assess mediator profiles and assessed the albumin ratio and viral load, in samples from a Health Protection Agency study. I examined profiles with respect to aetiology, disease severity and outcome and compared this with histopathology tissue and a blood-brain barrier model. Results In the context of a pandemic influenza virus, existing mechanisms identified limited cases, and a smartphone application was developed to collect real-time data. Delays in lumbar puncture and sub-optimal sample collection were identified, in association with a lower viral load. A lumbar puncture pack improved sample collection. Mediator profiles differed between those with an infectious versus immune-mediated aetiology, and those of unknown aetiology best reflected infectious; particularly myeloperoxidase, in part relating to neutrophils in cerebrospinal fluid and parenchyma. The interleukin1 antagonists, IL1RA and IL10, were associated with coma and outcome; and IL10 with reduced blood-brain barrier permeability. Adhesion molecules may counteract this, in both clinical samples and the model. Conclusions Current limitations of detection may be augmented with novel real-time technologies. Diagnosis is limited by delayed and sub-optimal sample collection, which can be improved with a simple pack. Mediators profiles may assist in the distinction of infectious from immune-mediated encephalitis, and cytokines that act against IL1 correlated with clinical severity and outcome. This may be more closely associated with outcome than viral load, although this may reflect sample timing. These findings should direct future research to develop approaches for improved diagnostics and adjunctive therapies.
Explicit representations by halfspaces of the edge cone of a graph
Creators: name: Valencia, Carlos E.
name: Villarreal, Rafael H.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C69, 13F55

description: Let G be an arbitrary simple graph. The main results are explicit representations of the edge cone of G as a finite intersection of closed halfspaces. If G is bipartite and connected we determine the facets of the edge cone and present a canonical irreducible representation.
Modeling nuclear blebs in a nucleoskeleton of independent filament networks.
Creators: name: Wren, Nicholas S.
name: Zhixia  Zhong
name: Schwartz, Russell
name: Dahl, Kris N.
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Correlations between altered nuclear shape and disease are empirically observed, but the causes of nuclear dysmorphisms are poorly understood. The nucleoskeleton, which provides the majority of the mechanical stability of the nucleus, is composed primarily of intermediate filaments of lamin proteins. The nucleoskeleton forms a mostly-planar network between the inner nuclear membrane and chromatin. It is unclear if blebs and larger scale changes in nuclear morphology are consequences of reorganization of the nucleoskeleton alone or of other cellular processes. To test this, we computationally recapitulate the lamina network using a mechanical network model created as a network of Hookean springs. A- and B-type lamin filaments were distributed over a spherical surface into distinct networks linked to one another by lamin-associated proteins. Iterative force-based adjustment of the network structure, together with a stochastically modified Bell model of bond breakage and formation, simulates nucleoskeleton reorganization with blebs. The rate of bleb retraction into the nucleus depends on both initial size of the bleb and number of networks being deformed. Our results show that induced blebs are more stable when only one filament component is deformed or when the networks have no interconnections. Also, the kinetics of retraction is influenced by the composition of the bleb. These results match with our experiments and others.
title: Transcription du manuscrit de Semur-en-Auxois, Bibliothèque Municipale, ms. 1, p. 136
Creators: name: Aubert, Eduardo Henrik
name: Brochard, Pierre
name: Aubert, Eduardo Henrik
name: Brochard, Pierre
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: Laboratoire de médiévistique occidentale de Paris
subject: Semur-en-Auxois
subject: LaMOP

description: Transcription du manuscrit de Semur-en-Auxois, Bibliothèque Municipale, ms. 1, p. 136

production-software: eScriptorium + Kraken version 3.0.13 (PageXml)
description: Source: https://www.nakala.fr/10.34847/nkl.7f8es623
description: Source: https://www.nakala.fr/10.34847/nkl.e905tdea
description: Relation: https://lamop.hypotheses.org/
description: Transcription du manuscrit Semur-en-Auxois, Bibliothèque Municipale, ms. 1
description: Transcription du manuscrit Semur-en-Auxois, Bibliothèque Municipale, ms. 1
A note on approximate Karush-Kuhn-Tucker conditions in locally Lipschitz multiobjective optimization
Creators: name: Van Tuyen, Nguyen
name: Yao, Jen-Chih
name: Wen, Ching-Feng
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 90C29, 90C46, 49J52

description: In the recent paper of Giorgi, Jiménez and Novo (J Optim Theory Appl 171:70--89, 2016), the authors introduced the so-called approximate Karush-Kuhn-Tucker (AKKT) condition for smooth multiobjective optimization problems and obtained some AKKT-type necessary optimality conditions and sufficient optimality conditions for weak efficient solutions of such a problem. In this note, we extend these optimality conditions to locally Lipschitz multiobjective optimization problems using Mordukhovich subdifferentials. Furthermore, we prove that, under some suitable additional conditions, an AKKT condition is also a KKT one.
description: 12 pages
A spectroscopic atlas of post-AGB stars and planetary nebulae selected from the IRAS Point Source Catalogue
Creators: name: Suarez, O.
name: Garcia-Lario, P.
name: Manchado, A.
name: Manteiga, M.
name: Ulla, A.
name: Pottasch, S. R.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Aims: We study the optical spectral properties of a sample of stars showing far infrared colours similar to those of well-known planetary nebulae. The large majority of them were unidentified sources or poorly known in the literature at the time when this spectroscopic survey started, some 15 years ago. Methods: We present low-resolution optical spectroscopy, finding charts and improved astrometric coordinates of a sample of 253 IRAS sources. Results: We have identified 103 sources as post-AGB stars, 21 as ``transition sources'', and 36 as planetary nebulae, some of them strongly reddened. Among the rest of sources in the sample, we were also able to identify 38 young stellar objects, 5 peculiar stars, and 2 Seyfert galaxies. Up to 49 sources in our spectroscopic sample do not show any optical counterpart, and most of them are suggested to be heavily obscured post-AGB stars, rapidly evolving on their way to becoming planetary nebulae. Conclusions: An analysis of the galactic distribution of the sources identified as evolved stars in the sample is presented together with a study of the distribution of these stars in the IRAS two-colour diagram. Finally, the spectral type distribution and other properties of the sources identified as post-AGB in this spectroscopic survey are discussed in the framework of stellar evolution.
description: 69 pages, 413 figures. Accepted by Astronomy and Astrophysics
title: Charlotte Smith and the Sonnet
Creators: name: Roberts, Bethan
Publisher: name: University of Liverpool Repository
Year: 2020

description: This thesis considers the place of Charlotte Smith’s Elegiac Sonnets in the eighteenth-century sonnet revival. Smith is often credited with reviving the sonnet form, and has attracted attention as a ‘Romantic’ poet. This thesis seeks to rebalance the existing critical focus by locating Smith’s sonnets in their eighteenth-century context and by considering her engagement with tradition alongside her innovation and influence. It offers a new history and evaluation of the eighteenth-century sonnet, and locates Smith’s sonnets within it. It traces the expansion of Elegiac Sonnets through its multiple editions from 1784 to 1800, charting Smith’s changing approach to – and the interactions between – form, literary tradition and place. Thus, the thesis clarifies Smith’s real significance as a writer and her place in literary history.
Littorella uniflora Asch.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Plantaginaceae
Littorella
Littorella uniflora

description: Littorella lacustris Linnaeus, Mantissa Plantarum Altera: 295. 1771, nom. illeg.
["Habitat in Europae littora lacuum."] Sp. Pl. 1: 115 (1753). RCN: 7118.
 Replaced synonym: Plantago uniflora L. (1753).
Type not designated.
Original material: as replaced synonym.
 Current name: Littorella uniflora (L.) Asch. (Plantaginaceae).
 Note: A. superfluous name for Plantago uniflora L. (1753).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 637, DOI: 10.5281/zenodo.291971
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Cart. 185 (11 H 70), f. 0059v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0059v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0059v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Extension to the Super-Weyl-K{\" a}hler Symmetry in Anomaly Mediation
Creators: name: Nishihara, Koske
name: Kubota, Takahiro
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Anomaly mediation mechanism of supersymmetry breaking is known to have an unsatisfactory aspect which is often referred to as the tachyonic slepton problem. A possible way out of this difficulty is investigated by considering the mediation mechanism not only of the super-Weyl but of K{\" a}hler part of anomaly. A new formula for the scalar mass squared is presented by including the effect of the K{\" a}hler anomaly. On the basis of the new formulae, the gauge non-singlet scalar mass squared is shown to be positive provided that the superpotential in the hidden sector satisfies a certain condition. The gauge singlet scalar mass squared may also be positive if we consider the threshold correction.
description: 11 pages, 2 figures
Mitotic inhibition of GRASP65 organelle tethering involves Polo-like kinase 1 (PLK1) phosphorylation proximate to an internal PDZ ligand.
Creators: name: Debrup  Sengupta
name: Linstedt, Adam
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: GRASP65 links cis-Golgi cisternae via a homotypic, N-terminal PDZ interaction, and its mitotic phosphorylation disrupts this activity. Neither the identity of the PDZ ligand involved in the GRASP65 self-interaction nor the mechanism by which phosphorylation inhibits its interaction is known. Phospho-mimetic mutation of known cyclin-dependent kinase 1/cyclin B sites, all of which are in the C-terminal "regulatory domain" of the molecule, failed to block organelle tethering. However, we identified a site phosphorylated by Polo-like kinase 1 (PLK1) in the GRASP65 N-terminal domain for which mutation to aspartic acid blocked tethering and alanine substitution prevented mitotic Golgi unlinking. Further, using interaction assays, we discovered an internal PDZ ligand adjacent to the PLK phosphorylation site that was required for tethering. These results reveal the mechanism of phosphoinhibition as direct inhibition by PLK1 of the PDZ ligand underlying the GRASP65 self-interaction.
Loasa urens Jacq. (Apr 1767
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Cornales
Loasaceae
Loasa
Loasa urens

description: Loasa hispida Linnaeus, Systema Naturae, ed. 12, 2: 364. 1767, nom. illeg.
RCN: 3880.
 Replaced synonym: Loasa urens Jacq. (1767).
Type not designated.
 Current name: Loasa urens Jacq. (Loasaceae).
 Note: Loasa hispida L. (Sep 1767) is a superfluous name for Loasa urens Jacq. (Apr 1767).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 637, DOI: 10.5281/zenodo.291971
Barriers and Patterns of Utilization of Dental Care Services among Marginalized Youth: A Scoping Review
Creators: name: Jaskaran Singh Beniwal
name: Pranav Vaishampayan
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Dental Public Health and Education
subject: Other Dentistry
subject: Public Health
subject: Medicine and Health Sciences
subject: Epidemiology
subject: International Public Health
subject: Dentistry
subject: FOS: Clinical medicine
subject: access to oral care
subject: access to oral health
subject: barriers to oral care
subject: barriers to oral health
subject: dental care
subject: marginalized youth
subject: oral health
subject: scoping review

description: The purpose of this scoping review is to examine the current literature concerning access to and the barriers restricting the utilization of oral healthcare services for marginalized youth globally.
Mitogen-activated protein kinase kinase 1-dependent Golgi unlinking occurs in G2 phase and promotes the G2/M cell cycle transition.
Creators: name: Feinstein, Timothy N.
name: Linstedt, Adam
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Two controversies have emerged regarding the signaling pathways that regulate Golgi disassembly at the G(2)/M cell cycle transition. The first controversy concerns the role of mitogen-activated protein kinase activator mitogen-activated protein kinase kinase (MEK)1, and the second controversy concerns the participation of Golgi structure in a novel cell cycle "checkpoint." A potential simultaneous resolution is suggested by the hypothesis that MEK1 triggers Golgi unlinking in late G(2) to control G(2)/M kinetics. Here, we show that inhibition of MEK1 by RNA interference or by using the MEK1/2-specific inhibitor U0126 delayed the passage of synchronized HeLa cells into M phase. The MEK1 requirement for normal mitotic entry was abrogated if Golgi proteins were dispersed before M phase by treatment of cells with brefeldin A or if GRASP65, which links Golgi stacks into a ribbon network, was depleted. Imaging revealed that unlinking of the Golgi apparatus begins before M phase, is independent of cyclin-dependent kinase 1 activation, and requires MEK signaling. Furthermore, expression of the GRASP family member GRASP55 after alanine substitution of its MEK1-dependent mitotic phosphorylation sites inhibited both late G(2) Golgi unlinking and the G(2)/M transition. Thus, MEK1 plays an in vivo role in Golgi reorganization, which regulates cell cycle progression.
Additional file 1: of Hepatitis B infection in the general population of China: a systematic review and meta-analysis
Creators: name: Wang, Huai
name: Men, Peixuan
name: Xiao, Yufeng
name: Gao, Pei
name: Lv, Min
name: Yuan, Qianli
name: Chen, Weixin
name: Bai, Shuang
name: Wu, Jiang
Publisher: name: figshare
Year: 2019
Subjects: Space Science
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology

description: Table S1. Cross-Sectional/Prevalence Study Quality Assessment Forms (AHRQ). (DOCX 16 kb)