cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(500636) Jane Brown
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(500638) Robert Hawdon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Stochastic dynamics of virus capsid formation: direct versus hierarchical self-assembly
Creators: name: Baschek, Johanna E.
name: Klein, Heinrich C. R.
name: Schwarz, Ulrich S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Subcellular Processes (q-bio.SC)
subject: FOS: Biological sciences

description: In order to replicate within their cellular host, many viruses have developed self-assembly strategies for their capsids which are sufficiently robust as to be reconstituted in vitro. Mathematical models for virus self-assembly usually assume that the bonds leading to cluster formation have constant reactivity over the time course of assembly (direct assembly). In some cases, however, binding sites between the capsomers have been reported to be activated during the self-assembly process (hierarchical assembly). In order to study possible advantages of such hierarchical schemes for icosahedral virus capsid assembly, we use Brownian dynamics simulations of a patchy particle model that allows us to switch binding sites on and off during assembly. For T1 viruses, we implement a hierarchical assembly scheme where inter-capsomer bonds become active only if a complete pentamer has been assembled. We find direct assembly to be favorable for reversible bonds allowing for repeated structural reorganizations, while hierarchical assembly is favorable for strong bonds with small dissociation rate, as this situation is less prone to kinetic trapping. However, at the same time it is more vulnerable to monomer starvation during the final phase. Increasing the number of initial monomers does have only a weak effect on these general features. The differences between the two assembly schemes become more pronounced for more complex virus geometries, as shown here for T3 viruses, which assemble through homogeneous pentamers and heterogeneous hexamers in the hierarchical scheme. In order to complement the simulations for this more complicated case, we introduce a master equation approach that agrees well with the simulation results.
description: Revtex, 31 pages, 9 EPS figures
A mixed-methods study to understand the impact of practitioner and organizational factors on fidelity of a child maltreatment prevention intervention in community-based settings
Creators: name: Bright, Charlotte L.
name: DePanfilis, Diane
name: Bartley, Leah
Publisher: name: SAGE Publications Ltd
Year: 2021

description: It has been well-documented that the degree to which interventions are implemented with fidelity in typical service settings has varied. Frequently, interventions are developed and tested in highly controlled or early adopter settings. Less attention has been given to what implementation looks like in usual care, and which factors promote practitioners' ability to implement with fidelity. Individuals and organizations implementing interventions in the real world receive varying levels of external supports and may apply a new intervention unaided. The purpose of this mixed-methods study was to explore factors that support implementation as intended in local community agencies. In the quantitative phase of this study, 32 case planners implementing Family Connections (FC), a child maltreatment preventive intervention, completed a survey about their perceptions of practitioner and organizational factors related to fidelity. The survey data were connected to case-level fidelity scores to understand the relationship between perceptions and fidelity. The qualitative phase of this study involved further exploration with nine case planner interviews and two separate focus groups with supervisors and agency leadership. The results of this study suggest that supervision is a key contributor to a practitioner's ability to implement an intervention in usual care. The quantitative and qualitative results suggest supervision, including supervisors’ perseverance, proactiveness, knowledge, availability, and skill reinforcement are important components of enhancing a practitioners' ability to learn and use FC. The quantitative results suggest that the level of education was positively associated with fidelity and perceptions of the intervention's limitations may be negatively related to implementation. Additional components that influence implementation for future research emerged from the qualitative phase related to system expectations and policies, individual practitioner attributes, and characteristics of the intervention.
Cost savings of paper analytical devices (PADs) to detect substandard and falsified antibiotics: Kenya case study
Creators: name: Lieberman, Marya
name: Laing, Sarah K.
name: Chen, Hui-Han
name: Bliese, Sarah L.
name: Higgins, Colleen
name: Ozawa, Sachiko
Publisher: name: SAGE Publications Ltd
Year: 2021

description: Background: Over 10% of antibiotics in low- and middle-income countries (LMICs) are substandard or falsified. Detection of poor-quality antibiotics via the gold standard method, high-performance liquid chromatography (HPLC), is slow and costly. Paper analytical devices (PADs) and antibiotic paper analytical devices (aPADs) have been developed as an inexpensive way to estimate antibiotic quality in LMICs. Aim: To model the impact of using a rapid screening tools, PADs/aPADs, to improve the quality of amoxicillin used for treatment of childhood pneumonia in Kenya. Methods: We developed an agent-based model, ESTEEM (Examining Screening Technologies with Economic Evaluations for Medicines), to estimate the effectiveness and cost savings of incorporating PADs and aPADs in amoxicillin quality surveillance in Kenya. We compared the current testing scenario (batches of entire samples tested by HPLC) with an expedited HPLC scenario (testing smaller batches at a time), as well as a screening scenario using PADs/aPADs to identify poor-quality amoxicillin followed by confirmatory analysis with HPLC. Results: Scenarios using PADs/aPADs or expedited HPLC yielded greater incremental benefits than the current testing scenario by annually averting 586 (90% uncertainty range (UR) 364-874) and 221 (90% UR 126-332) child pneumonia deaths, respectively. The PADs/aPADs screening scenario identified and removed poor-quality antibiotics faster than the expedited or regular HPLC scenarios, and reduced costs significantly. The PADs/aPADs scenario resulted in an incremental return of $14.9 million annually compared with the reference scenario of only using HPLC. Conclusion: This analysis shows the significant value of PADs/aPADs as a medicine quality screening and testing tool in LMICs with limited resources.
(500639) Charles Ferraby
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
On the Required Number of Antennas in a Point-to-Point Large-but-Finite MIMO System: Outage-Limited Scenario
Creators: name: Makki, Behrooz
name: Svensson, Tommy
name: Eriksson, Thomas
name: Alouini, Mohamed-Slim
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: This paper investigates the performance of the point-to-point multiple-input-multiple-output (MIMO) systems in the presence of a large but finite numbers of antennas at the transmitters and/or receivers. Considering the cases with and without hybrid automatic repeat request (HARQ) feedback, we determine the minimum numbers of the transmit/receive antennas which are required to satisfy different outage probability constraints. Our results are obtained for different fading conditions and the effect of the power amplifiers efficiency on the performance of the MIMO-HARQ systems is analyzed. Moreover, we derive closed-form expressions for the asymptotic performance of the MIMO-HARQ systems when the number of antennas increases. Our analytical and numerical results show that different outage requirements can be satisfied with relatively few transmit/receive antennas.
description: Under review in IEEE Transactions on Communications
Decomposing virulence to understand bacterial clearance in persistent infections
Creators: name: Acuña Hidalgo, Beatriz
name: Silva, Luís M.
name: Franz, Mathias
name: Regoes, Roland R.
name: Armitage, Sophie A. O.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: evolutionary ecology
subject: pathogens
subject: persistent infections
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Following an infection, hosts cannot always clear the pathogen, instead either dying or surviving with a persistent infection. Such variation is ecologically and evolutionarily important because it can affect infection prevalence and transmission, and virulence evolution. However, the factors causing variation in infection outcomes, and the relationship between clearance and virulence are not well understood. Here we show that sustained persistent infection and clearance are both possible outcomes across bacterial species showing a range of virulence in Drosophila melanogaster. Variation in virulence arises because of differences in the two components of virulence: bacterial infection intensity inside the host (exploitation), and the amount of damage caused per bacterium (per parasite pathogenicity). As early-phase exploitation increased, clearance rates later in the infection decreased, whereas there was no apparent effect of per parasite pathogenicity on clearance rates. Variation in infection outcomes is thereby determined by how virulence – and its components – relate to the rate of pathogen clearance. Taken together we demonstrate that the virulence decomposition framework is broadly applicable and can provide valuable insights into host-pathogen interactions.
Sexual function in adult patients who have undergone augmentation surgery in childhood: what is really important?
Creators: name: Bañuelos Marco, Beatriz
name: Hiess, Manuela
name: Stein, Raimund
name: Gonzalez, Ricardo
name: Lingnau, Anja
name: Wood, Dan
name: Radford, Anna
name: Haid, Bernhard
name: Pediatric Urology Group Of The EAU Young Academic Urologists
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Erectile Dysfunction
subject: Sexual Behavior
subject: Spinal Dysraphism
subject: Urinary Incontinence
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Problems relating to the development of a healthy approach to sex and intimacy during puberty, after augmentation cystoplasty, are scarcely discussed in literature. Therefore, this may suggest that such issues are insufficiently addressed by pediatric urologists. We gathered four experts in the field as well as an experienced leader of a patient group and mother of a girl with spina bifida and asked questions relevant to the following areas of care: (a) diversion, urinary incontinence, and sexual life; (b) impact of a stoma on body image perception and self-esteem; (c) specific female concerns with regard to fertility and recurrent urinary infections; (d) specific male concerns on anejaculation and erectile dysfunction. Their answers are discussed in view of the available literature. All experts and the patient group representative agreed that most of these patients will experience: lack of self-confidence as the most frequent obstacle to starting a relationship and incontinence as a barrier to sexual activity. The cosmesis of the stoma and abdominal scars might influence self-esteem and therefore the sexual activity, however it appears to be a less common concern in males than females. Our results outline the importance and influence that the body image, self-esteem, and confidence present for the individual expectations of the patients related to sex life and sexual activity. Physicians should be encouraged to ask all postpubertal patients about their sexual concerns at every visit. Further studies and exchange of information between clinicians are needed to provide meaningful and analyzable patient-related outcome measures (PROMs).
Using Design Thinking to Explore Rural Experiential Education Barriers and Opportunities
Creators: name: Wolcott, Michael D.
name: Williams, Charlene R.
name: Hubbard, Devin K.
name: McLaughlin, Jacqueline E.
name: Kiser, Stephanie N.
Publisher: name: SAGE Publications Ltd
Year: 2021

description: Introduction: Design thinking is a creative problem-solving framework that can be used to better understand challenges and generate solutions in health professions education, such as the barriers to rural education. Rural education experiences can benefit students, providers, and patients; however, placement in and maintenance of rural education experiences offer unique challenges. Design thinking offers strategies to explore and address these challenges. Methods: This study used a design thinking framework to identify barriers of student placement in rural locations; this was accomplished using strategies to empathize with users (eg, students, practitioners, and administrators) and define the problem. Data were collected from focus groups, interviews, and a design thinking workshop. Design activities promoted participant discussion by drawing pictures, discussing findings, and creating empathy maps of student experiences. Qualitative data were analyzed to identify salient barriers to rural experience selection and opportunities for support. Result: Focus group (n=6), interview (n=13), and workshop participants (n=18) identified substantial advantages (eg, exposure to a wider variety of patients, less bureaucracy and constraints, more time with faculty) and disadvantages (eg, isolation, lack of housing, and commuting distances) of rural experiences. Participants identified physical, emotional, and social isolation as a significant barrier to student interest in and engagement in rural experiences. Workshop participants were able to generate over 100 ideas to address the most prominent theme of isolation. Discussion: Design thinking strategies can be used to explore health professions education challenges, such as placement in rural settings. Through engagement with students, practitioners, and administrators it was identified that physical, social, and emotional isolation presents a significant barrier to student placement in rural experiences. This perspective can inform support systems for students, preceptors, and communities that participate in rural educational experiences.
การประเมินการดูแลผู้ป่วยเบาหวานที่มารับบริการที่โรงพยาบาลชุมพลบุรีจังหวัดสุรินทร์โดยการตรวจระดับน้ำตาลสะสม HemoglobinA1c
Creators: name: รัตนาภรณ์ ฮิมหมั่นงาน
Publisher: name: กองนวัตกรรมและวิจัย กรมควบคุมโรค
Year: 2551
Subjects: การดูแลผู้ป่วยเบาหวาน
โรงพยาบาลชุมพลบุรี
จังหวัดสุรินทร์

description: วารสารควบคุมโรค, 34, 1, 1-10
Phases and approximations of baryonic popcorn in a low-dimensional analogue of holographic QCD
Creators: name: Elliot-Ripley, Matthew
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The Sakai-Sugimoto model is the most pre-eminent model of holographic QCD, in which baryons correspond to topological solitons in a five-dimensional bulk spacetime. Recently it has been shown that a single soliton in this model can be well approximated by a flat-space self-dual Yang-Mills instanton with a small size, although studies of multi-solitons and solitons at finite density are currently beyond numerical computations. A lower-dimensional analogue of the model has also been studied in which the Sakai-Sugimoto soliton is replaced by a baby Skyrmion in three spacetime dimensions with a warped metric. The lower dimensionality of this model means that full numerical field calculations are possible, and static multi-solitons and solitons at finite density were both investigated, in particular the baryonic popcorn phase transitions at high densities. Here we present and investigate an alternative lower-dimensional analogue of the Sakai-Sugimoto model in which the Sakai-Sugimoto soliton is replaced by an $O(3)$-sigma model instanton in a warped three-dimensional spacetime stabilised by a massive vector meson. A more detailed range of baryonic popcorn phase transitions are found, and the low-dimensional model is used as a testing ground to check the validity of common approximations made in the full five-dimensional model, namely approximating fields using their flat-space equations of motion, and performing a leading order expansion in the metric.
description: 16 pages, 5 figures
What does the OECD-FAO Agricultural Outlook 2017-2026 imply for income distribution in the Sudan and Ethiopia
Creators: name: Artavia Oreamuno, Marco A.
name: Siddig, Khalid
name: Artavia Oreamuno, Marco A.
name: Siddig, Khalid
Publisher: name: Unknown
Year: 2020
Subjects: subject: Agricultural and Food Policy
subject: Community/Rural/Urban Development
subject: Food Consumption/Nutrition/Food Safety
subject: International Development
subject: Resource /Energy Economics and Policy
subject: OECD-FAO Agricultural Outlook
subject: Sudan
subject: Ethiopia
subject: economy-wide analysis

description: The OECD and FAO provide growth paths (projections over a period of 10 years) for the agricultural sectors of different countries in their joint OECD-FAO Agricultural Outlook. This study assesses the implication of the projected agricultural growth paths for the Sudan and Ethiopia on the structures of the economies and the distribution of incomes among the different household groups in the two countries. First, single country, recursive dynamic computable general equilibrium (CGE) models for the two countries were calibrated to the most recent social accounting matrices (SAMs) of the two countries. Second, a baseline scenario for each country was developed until 2026. These projections were based on GDP projections (value, growth rates and composition) developed by the IMF World Economic Outlook, the World Bank World Development Indicators and the national statistical offices in the two countries. Third, the growth paths of the OECD-FAO Agricultural Outlook were implemented for the agricultural sectors of the two countries while preserving the aggregate GDP projections. Finally, results of the models under the OEDC-FAO growth paths are reported with a special focus on the distribution of income in the two countries. The main findings highlight that, in both countries, agricultural growth is significantly behind that of industry and services. Due to the slower growth, returns to factors of production (e.g. labor and capital) employed in agriculture are much lower than to those employed in the other economic sectors. Unless sensible interventions are made, poor agricultural households will be particularly worse-off within these two countries. Therefore, economic and agricultural policies in these two countries should pay more attention to agricultural sector growth (productivity) within their poverty reduction/eradication efforts.
Drought legacy effects on root morphological traits and plant biomass via soil biota feedback
Creators: name: Lozano, Yudi M.
name: Aguilar-Trigueros, Carlos A.
name: Ospina, Jenny M.
name: Rillig, Matthias C.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: aboveground–belowground interactions
subject: global change drivers
subject: plant–soil feedback
subject: plant–soil interactions
subject: root morphological traits
subject: soil conditioned by drought
subject: soil fungal communities
subject: soil inoculum
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: 1. Drought causes soil feedback effects on plant performance. However, how the linkages between conditioned soil biota and root traits contribute to explain plant–soil feedback (PSF) as a function of drought is unknown. 2. We utilized soil inoculum from a conditioning experiment where grassland species grew under well-watered and drought conditions, and their soil fungi were analyzed. Under well-watered conditions, we grew 21 grassland species with those inocula from either conspecific or heterospecific soils. At harvest, plant biomass and root traits were measured. 3. Negative PSF (higher biomass in heterospecific than in conspecific soils) was predominant, and favored in drought-conditioned soils. Previous drought affected the relationship between root traits and fungal groups. Specific root surface area (SRSA) was higher in heterospecific than in conspecific droughted soils and was linked to an increase in saprotroph richness. Overall, root diameter was higher in conspecific soils and was linked to mutualist and pathogen composition, whereas the decrease of root : shoot in heterospecific soils was linked to pathogenic fungi. 4. Drought legacy affects biomass and root morphological traits via conditioned soil biota, even after the drought conditions have disappeared. This provides new insights into the role that soil biota have modulating PSF responses to drought.
(500627) Margaret Reily
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(500630) Thomas William Gibson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(500637) Robert Middlemas
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The Soundproof Model of an Acoustic–internal Waves System with Low Stratification
Creators: name: Bresch, Didier
name: Klein, Rupert
name: Liu, Xin
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Internal waves
subject: Acoustic waves
subject: Low stratification
subject: Soundproof approximation
subject: 500 Naturwissenschaften und Mathematik::510 Mathematik::510 Mathematik

description: This work is devoted to investigating a compressible fluid system with low stratification, which is driven by fast acoustic waves and internal waves. The approximation using a soundproof model is justified. More precisely, the soundproof model captures the dynamics of both the non-oscillating mean flows and the oscillating internal waves, while filters out the fast acoustic waves, of the compressible system with or without initial acoustic waves. Moreover, the fast-slow oscillation structure is investigated.
(500626) Jane Ferry
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(500629) Thomas Gibson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Patient preferences for development in MRI scanner design: a survey of claustrophobic patients in a randomized study
Creators: name: Iwan, Elisa
name: Yang, Jinhua
name: Enders, Judith
name: Napp, Adriane Elisabeth
name: Rief, Matthias
name: Dewey, Marc
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Claustrophobia
subject: Magnetic resonance imaging
subject: Questionnaire
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objective: To investigate which magnetic resonance imaging (MRI) scanner designs claustrophobic patients prefer. Material/methods: We analyzed questionnaires completed by 160 patients at high risk for claustrophobia directly after a scan in either a short-bore or open panoramic scanner as part of a prospective randomized trial Enders et al (BMC Med Imaging 11:4, 2011). Scanner preferences were judged based on schematic drawings of four scanners. Information on the diagnostic performance of the depicted scanners was provided, too. Results: A majority of patients suggested upright open (59/160, 36.9%) and open panoramic (53/160, 33.1%) before short-bore designs (26/160, 16.3%, for all p < 0.001) for future development. When asked about patients' preferred scanner choice for an upcoming examination, information about a better diagnostic performance of a short-bore scanner significantly improved its preference rates (from 6/160 to 49/160 or 3.8 to 30.5%, p < 0.001). Patients with a claustrophobic event preferred open designs significantly more often than patients without a claustrophobic event (p = 0.047). Patients scanned in a short-bore scanner in our trial preferred this design significantly more often (p = 0.003). Noise reduction (51/160, 31.9%), more space over the head (44/160, 27.5%), and overall more space (33/160, 20.6%) were the commonest suggested areas of improvement. Conclusion: Patients at high risk for claustrophobia visually prefer open- over short-bore MRI designs for further development. Education about a better diagnostic performance of a visually less-attractive scanner can increase its acceptance. Noise and space were of most concern for claustrophobic patients. This information can guide individual referral of claustrophobic patients to scanners and future scanner development. Key points: • Patients at high risk for claustrophobia visually favor the further development of open scanners as opposed to short- and closed-bore scanner designs. • Educating claustrophobic patients about a higher diagnostic performance of a short-bore scanner can significantly increase their acceptance of this otherwise visually less-attractive design. • A medical history of earlier claustrophobic events in a given MRI scanner type and focusing on the features "more space" and "noise reduction" can help to guide referral of patients who are at high risk for claustrophobia.
(500622) William R. Watson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Medical Student Leadership Development through a Business School Partnership Model: A Case Study and Implementation Strategy
Creators: name: Storrie, Mindy
name: Byerley, Julie S.
name: Daaleman, Timothy P.
name: Gilliland, Kurt O.
name: Beck Dallaghan, Gary
name: Smithson, Sarah
Publisher: name: SAGE Publications Ltd
Year: 2021

description: Background: There is an ongoing call for leadership development in academic health care and medical students desire more training in this area. Although many schools offer combined MD/MBA programs or leadership training in targeted areas, these programs do not often align with medical school leadership competencies and are limited in reaching a large number of students.Methods:The Leadership Initiative (LI) was a program created by a partnership between a School of Medicine (SOM) and Business School with a learning model that emphasized the progression from principles to practice, and the competencies of self-awareness, communication, and collaboration/teamwork. Through offerings across a medical school curriculum, the LI introduced leadership principles and provided an opportunity to apply them in an interactive activity or simulation. We utilized the existing SOM evaluation platform to collect data on program outcomes that included satisfaction, fidelity to the learning model, and impact.Results:From 2017 to 2020, over 70% of first-year medical students participated in LI course offerings while a smaller percentage of fourth-year students engaged in the curriculum. Most students had no prior awareness of LI course material and were equivocal about their ability to apply lessons learned to their medical school experience. Students reported that the LI offerings provided opportunities to practice the skills and competencies of self-awareness, communication, and collaboration/teamwork.Discussion: Adding new activities to an already crowded medical curriculum was the greatest logistical challenge. The LI was successful in introducing leadership principles but faced obstacles in having participants apply and practice these principles. Most students reported that the LI offerings were aligned with the foundational competencies.
Improved chiral nucleon-nucleon potential up to next-to-next-to-next-to-leading order
Creators: name: Epelbaum, E.
name: Krebs, H.
name: Meißner, U. -G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present improved nucleon-nucleon potentials derived in chiral effective field theory up to next-to-next-to-next-to-leading order. We argue that the nonlocal momentum-space regulator employed in the two-nucleon potentials of Refs. [E. Epelbaum, W. Gloeckle, U.-G. Meißner, Nucl. Phys. A747 (2005) 362], [D.R. Entem, R. Machleidt, Phys. Rev. C68 (2003) 041001] is not the most efficient choice, in particular since it affects the long-range part of the interaction. We are able to significantly reduce finite-cutoff artefacts by using an appropriate regularization in coordinate space which maintains the analytic structure of the amplitude. The new potentials do not require the additional spectral function regularization employed in Ref. [E. Epelbaum, W. Gloeckle, U.-G. Meißner, Nucl. Phys. A747 (2005) 362] to cut off the short-range components of the two-pion exchange and make use of the low-energy constants c_i and d_i determined from pion-nucleon scattering without any fine tuning. We discuss in detail the construction of the new potentials and convergence of the chiral expansion for two-nucleon observables. We also introduce a new procedure for estimating the theoretical uncertainty from the truncation of the chiral expansion that replaces previous reliance on cutoff variation.
description: 34 pages, 13 figures, 7 tables
Couple communication and contraception use in urban Senegal
Creators: name: Frerichs, Leah
name: Corneli, Amy
name: Domino, Marisa Elena
name: Grabert, Brigid K
name: Speizer, Ilene S.
name: Fried, Bruce J.
Publisher: name: SAGE Publications Ltd
Year: 2021

description: Objectives: Couple communication about family planning has been shown to increase uptake of contraception. However, couple communication is often measured based solely on one partner?s report of communication. This research investigates the influence of couple-reported communication about family planning on current and future use of contraception using couple-level data. Methods: We used baseline data from the Measurement, Learning, and Evaluation (MLE) project collected through household surveys in 2011 from a cross-sectional representative sample of women and men in urban Senegal to conduct secondary data analysis. We used multivariable logit models to estimate the average marginal effects of couple communication about family planning on current contraception use and future intention to use contraception. Results: Couple communication about family planning reported by both partners was significantly associated with an increased likelihood of current use of contraception and with future intention to use contraception among non-contracepting couples. Couples where one partner reported discussing family planning had a 25% point greater likelihood of current contraception use than couples where neither partner reported discussing, while couples where both partners reported discussing family planning had a 56% point greater likelihood of current contraception use, representing more than twice the effect size. Among couples not using contraception, couples where one partner reported discussing family planning had a 15% point greater likelihood of future intention to use contraception than couples where neither partner reported discussing, while couples where both partners reported discussing family planning had a 38% point greater likelihood of future intention to use contraception. Conclusion: These findings underscore the importance of the inclusion of both partners in family planning programs to increase communication about contraception and highlight the need for future research using couple-level data, measures, and analysis.
Long-term small-fiber neuropathy and pain sensitization in survivors of pediatric acute lymphoblastic leukemia after stem cell transplantation
Creators: name: Ruscher, Victoria
name: Lieber, Sascha
name: Kühl, Jörn-Sven
name: Schulte, Johannes
name: Blankenburg, Markus
name: Reindl, Tobias
name: Hernáiz Driever, Pablo
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Acute lymphoblastic leukemia
subject: Chemotherapy-induced peripheral neuropathy
subject: Quantitative sensory testing
subject: Small- and large nerve fibers
subject: Pain sensitization
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Purpose: We aimed at describing for the first time peripheral small-fiber neurotoxicity and pain sensitization in survivors of pediatric acute lymphoblastic leukemia after stem cell transplantation (SCT). Methods: In a cross-sectional, retrospective, single-center study, we assessed 25 relapse-free long-term survivors (median age at SCT: 11 ± 4.9 years; median time between SCT and testing: 8.25 years, 19 males) using a reduced version of the pediatric-modified total neuropathy score for clinical assessment and Quantitative Sensory Testing (QST). Inclusion criteria: ≥ 6 years old at testing, ≤ 18 years old at time of SCT, ≥ 1 year between SCT and testing. Results: Nine patients (36%) had peripheral neuropathy as defined by the clinical red-pmTNS (≥ 4). The QST parameters mechanical pain sensitivity, mechanical detection threshold, thermal sensory limen, vibration detection threshold and pressure pain threshold were significantly abnormal in the survivor cohort (p < 0.0038). Except for one, all survivors showed at least one abnormal QST parameter. When using QST, signs of small and large fiber dysfunction were present in 22 (88%) and 17 (68%) survivors, respectively. More than half of all survivors were found to experience pathologic sensitization to pain. Conclusions and implications for cancer survivors: Survivors of pediatric acute lymphoblastic leukemia after SCT are at high risk for long-term peripheral neuropathy with a dominating small-fiber and pain sensitization pattern.
Prevalence and risk factors of drug-related problems identified in pharmacy-based medication reviews
Creators: name: Sell, Raphael
name: Schaefer, Marion
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Community Pharmacy Services
subject: Inappropriate Prescribing
subject: Medication Reconciliation
subject: Medication Therapy Management
subject: Risk Factors
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Medication safety is a major health concern, especially for older patients, in whom drug-related problems occur frequently as a consequence of polypharmacy and frailty, increasing the risk of adverse drug events. Objective: To investigate the prevalence and types of drug-related problems in community pharmacies and to identify associated risk factors in order to adjust the focus of care. Setting: 300 German community pharmacies in Saxony-Anhalt (Germany). Method: In April 2015, community pharmacists conducted brown bag medication reviews for primary care patients, in which they identified and solved drug-related problems with patients or their physicians. Data from these reviews were analyzed, including frequency and nature of problems and their respective resolutions. Potentially inappropriate medications according to the PRISCUS list were identified by post hoc analysis. Risk factors for drug-related problems were determined using bivariate and multivariate logistic regression analysis. Main outcome measure: Prevalence and risk factors of drug-related problems. Results: 1090 medication reviews were conducted. On average, patients were 72.0 ± 9.1 years old and had 10.6 ± 3.7 medications, 62.0% (n = 676) presented a medication plan. Knowledge gaps about medications were detected in almost a third of patients (n = 345). Drug-related problems were identified in 84.2% (n = 918) of patients (in 3836 medications). Frequent problems concerned drug–drug-interactions (53.7%, n = 585) as well as drug use and adherence (46.7%, n = 509). Most problems (72.2%, n = 2769) were resolved between pharmacist and patient. Knowledge gaps and the number of drugs were independently associated with a higher risk of drug-related problems. For older patients, potentially inappropriate medications were a risk factor in bivariate, but not in multivariate analysis. Conclusion: Pharmacists identified and resolved considerable rates of drug-related problems, suggesting that they are capable and well-positioned to conduct medication reviews. Knowledge gaps, the number of drugs, patient age and, in older patients, potentially inappropriate medications may indicate an increased risk for drug-related problems.
Impact of ηearth on the capabilities of affordable space missions to detect biosignatures on extrasolar planets
Creators: name: Leger, Alain
name: Defrere, Denis
name: Malbet, Fabien
name: Labadie, Lucas
name: Absil, Olivier
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present an analytic model to estimate the capabilities of space missions dedicated to the search for biosignatures in the atmosphere of rocky planets located in the habitable zone of nearby stars. Relations between performance and mission parameters such as mirror diameter, distance to targets, and radius of planets, are obtained. Two types of instruments are considered: coronagraphs observing in the visible, and nulling interferometers in the thermal infrared. Missions considered are: single-pupil coronagraphs with a 2.4 m primary mirror, and formation flying interferometers with 4 x 0.75 m collecting mirrors. The numbers of accessible planets are calculated as a function of ηearth. When Kepler gives its final estimation for ηearth, the model will permit a precise assessment of the potential of each instrument. Based on current estimations, ηearth = 10% around FGK stars and 50% around M stars, the coronagraph could study in spectroscopy only ~1.5 relevant planets, and the interferometer ~14.0. These numbers are obtained under the major hypothesis that the exozodiacal light around the target stars is low enough for each instrument. In both cases, a prior detection of planets is assumed and a target list established. For the long-term future, building both types of spectroscopic instruments, and using them on the same targets, will be the optimal solution because they provide complementary information. But as a first affordable space mission, the interferometer looks the more promising in term of biosignature harvest.
description: Accepted by ApJ
Examining physical activity and quality of life in adults with autism spectrum disorder and intellectual disability
Creators: name: Hume, K.
name: Tomaszewski, B.
name: Savage, M.N.
Publisher: name: SAGE Publications Inc.
Year: 2021

description: Adults with autism and co-occurring intellectual disability engage in low levels of physical activity and are at increased risk of developing secondary health conditions attributed to physical inactivity compared to adults in the general population. Few studies have examined the use of objective measures to characterize physical activity levels for adults with autism and intellectual disability. The current study aimed to examine the relationship between physical activity, using an activity tracker, and quality of life in adults with autism and intellectual disability. In the current study, 38 adults with autism and intellectual disability, ages 18–55, wore a Fitbit Flex 2® activity tracker for 1 week, and completed the Quality of Life Questionnaire. The relationship between average daily step count quality of life was examined. Most adults in the sample were overweight and taking fewer daily steps than recommended guidelines. Increased average daily step count was significantly associated with quality of life.
(500624) James Hood
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Fission dynamics at low excitation energy. 2
Creators: name: Aritomo, Y.
name: Chiba, S.
name: Ivanyuk, F. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The mass asymmetry in the fission of U-236 at low excitation energy is clarified by the analysis of the trajectories obtained by solving the Langevin equations for the shape degrees of freedom. It is demonstrated that the position of the peaks in the mass distribution of fission fragments is determined mainly by the saddle point configuration originating from the shell correction energy. The width of the peaks, on the other hand, results from the shape fluctuations close to the scission point caused by the random force in the Langevin equation. We have found out that the fluctuations between elongated and compact shapes are essential for the fission process. According to our results the fission does not occur with continuous stretching in the prolate direction, similarly to that observed in starch syrup, but is accompanied by the fluctuations between elongated and compact shapes. This picture presents a new viewpoint of fission dynamics and the splitting mechanism.
description: 9 pages, 12 figures, submitted to Phys. Rev. C. arXiv admin note: substantial text overlap with arXiv:1310.3156