cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Petromus typicus A. Smith 1831
Creators: name: Woods, Charles A.
Publisher: name: Zenodo
Year: 1993
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Petromuridae
Petromus
Petromus typicus

description: Petromus typicus Smith, 1831. S. Afr. Quart. J., 1 (5): 11. TYPE LOCALITY: South Africa, "Mountains towards mouth of Orange River". DISTRIBUTION: W South Africa, Namibia, to SW Angola. STATUS: Common. SYNONYMS: ausensis, barbiensis, cinnamomeus, cunealis, greeni, guinasensis, karasensis, kobosensis, marjoriae, namaquensis, pallidior, tropicalis, windhoekensis. COMMENTS: Numerous subspecies have been named, most of which are invalid.
description: Published as part of Charles A. Woods, 1993, Order Rodentia - Suborder Hystricognathi, pp. 771-806 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on page 774, DOI: 10.5281/zenodo.7353083
City Knights: Urban Networking and City Life in Late Medieval Iberia
Creators: name: Rodriguez-Velasco, Jesus D.
Publisher: name: Columbia University
Year: 2012
Subjects: City and town life
Orders of knighthood and chivalry
Fraternal organizations
Social history--Medieval
History

description: Civil uprisings, urban networking, and civil life, no matter how contemporary it is, must also be historicized. The genealogy of current international issues of global nature raises also the question of how and by what means city life and urban networking became a crucial element for the opposition of central powers, and why collective practices of power where thus devised in order to fight against monarchical and oligarchical models. Historicizing the uprisings also means to investigate into the procedures whereby urban networking and city life established lists and programs of concrete requests and structures of control that were put forth for negotiation in legally constituted assemblies. Historicizing is definitely a way to understand the process whereby a society is created by means of processes of association and assembling or re-assembling, giving us, thus, a better understanding of social movements in general (Latour 2005). Medieval chivalry. Medieval bourgeois organizations. Fraternities. Brotherhoods.
Travelling Waves in Hall-MHD and the Ion-Acoustic Shock Structure
Creators: name: Hagstrom, George I.
name: Hameiri, Eliezer
Publisher: name: arXiv
Year: 2013
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Hall-MHD is a mixed hyperbolic-parabolic partial differential equation that describes the dynamics of an ideal two fluid plasma with massless electrons. We study the only shock wave family that exists in this system (the other discontinuities being contact discontinuities and not shocks). We study planar travelling wave solutions and we find solutions with discontinuities in the hydrodynamic variables, which arise due to the presence of real characteristics in Hall-MHD. We introduce a small viscosity into the equations and use the method of matched asymptotic expansions to show that solutions with a discontinuity satisfying the Rankine-Hugoniot conditions and also an entropy condition have continuous shock structures. The lowest order inner equations reduce to the compressible Navier-Stokes equations, plus an equation which implies the constancy of the magnetic field inside the shock structure. We are able to show that the current is discontinuous across the shock, even as the magnetic field is continuous, and that the lowest order outer equations, which are the equations for travelling waves in inviscid Hall-MHD, are exactly integrable. We show that the inner and outer solutions match, which allows us to construct a family of uniformly valid continuous composite solutions that become discontinuous when the diffusivity vanishes.
Approaches to ensuring and improving quality in the context of health system strengthening: a cross-site analysis of the five African Health Initiative Partnership programs
Creators: name: Philips, James F.
name: Finnegan, Karen
name: Baynes, Colin Duncan
name: Sherr, Kenneth
name: Chintu, Namwinga
name: Basinga, Paulin
name: Bawah, Ayaga A.
name: Anatole, Manzi
name: Awoonor-Williams, John Koku
name: Hirschhorn, Lisa R.
Publisher: name: Columbia University
Year: 2013
Subjects: Health care reform
Public policy (Law)
Public health

description: Background
Integrated into the work in health systems strengthening (HSS) is a growing focus on the importance of ensuring quality of the services delivered and systems which support them. Understanding how to define and measure quality in the different key World Health Organization building blocks is critical to providing the information needed to address gaps and identify models for replication.

Description of approaches
We describe the approaches to defining and improving quality across the five country programs funded through the Doris Duke Charitable Foundation African Health Initiative. While each program has independently developed and implemented country-specific approaches to strengthening health systems, they all included quality of services and systems as a core principle. We describe the differences and similarities across the programs in defining and improving quality as an embedded process essential for HSS to achieve the goal of improved population health. The programs measured quality across most or all of the six WHO building blocks, with specific areas of overlap in improving quality falling into four main categories: 1) defining and measuring quality; 2) ensuring data quality, and building capacity for data use for decision making and response to quality measurements; 3) strengthened supportive supervision and/or mentoring; and 4) operational research to understand the factors associated with observed variation in quality.

Conclusions
Learning the value and challenges of these approaches to measuring and improving quality across the key components of HSS as the projects continue their work will help inform similar efforts both now and in the future to ensure quality across the critical components of a health system and the impact on population health.
Spin correlated dielectric memory and rejuvenation in relaxor ferroelectric CuCrS2
Creators: name: Karmakar, A.
name: Dey, K.
name: Chatterjee, S.
name: Majumdar, S.
name: Giri, S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: CuCrS2, a Heisenberg antiferromagnet with layered edge sharing triangular lattice, exhibits a spiral magnetic order. Dielectric (E) and polarization studies show magnetoelectric (ME) coupling at Neel temperature (T_N=38 K) where simultaneous dielectric and magnetic long range order occur. The compound shows a diffused ferroelectric (FE) transition and slow relaxation dynamics above T_N, indicative of relaxor FE behavior. Interestingly, memory effect and magnetic field induced rejuvenation are also observed in E, establishing cooperative glassy dynamics and ME coupling even above T_N. We discuss the role of geometrical frustration and metal ligand hybridization for these unusual properties.
description: 5 pages, 3 figures
How Do Recommendation Models Amplify Popularity Bias? An Analysis from the Spectral Perspective
Creators: name: Lin, Siyi
name: Gao, Chongming
name: Chen, Jiawei
name: Zhou, Sheng
name: Hu, Binbin
name: Feng, Yan
name: Chen, Chun
name: Wang, Can
Publisher: name: arXiv
Year: 2024
Subjects: subject: Information Retrieval (cs.IR)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Recommendation Systems (RS) are often plagued by popularity bias. When training a recommendation model on a typically long-tailed dataset, the model tends to not only inherit this bias but often exacerbate it, resulting in over-representation of popular items in the recommendation lists. This study conducts comprehensive empirical and theoretical analyses to expose the root causes of this phenomenon, yielding two core insights: 1) Item popularity is memorized in the principal spectrum of the score matrix predicted by the recommendation model; 2) The dimension collapse phenomenon amplifies the relative prominence of the principal spectrum, thereby intensifying the popularity bias. Building on these insights, we propose a novel debiasing strategy that leverages a spectral norm regularizer to penalize the magnitude of the principal singular value. We have developed an efficient algorithm to expedite the calculation of the spectral norm by exploiting the spectral property of the score matrix. Extensive experiments across seven real-world datasets and three testing paradigms have been conducted to validate the superiority of the proposed method.
description: 14 pages, 7 figures
Thryonomyidae Pocock 1922
Creators: name: Woods, Charles A.
Publisher: name: Zenodo
Year: 1993
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Thryonomyidae

description: Family Thryonomyidae Pocock, 1922. Proc. Zool. Soc. London, 1922:423. COMMENTS: Several fossil forms from the Oligocene of North Africa.
description: Published as part of Charles A. Woods, 1993, Order Rodentia - Suborder Hystricognathi, pp. 771-806 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on page 775, DOI: 10.5281/zenodo.7353083
Additional file 1 of AMEND 2.0: module identification and multi-omic data integration with multiplex-heterogeneous graphs
Creators: name: Boyd, Samuel S.
name: Slawson, Chad
name: Thompson, Jeffrey A.
Publisher: name: figshare
Year: 2025
Subjects: Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Additional file1: Appendix. This file acts as an appendix for the main manuscript, covering the implementation of AMEND in R, mathematical details of transition matrix construction for RWR-MH, details on degree bias adjustment methods, and further details on the AMEND-DIABLO comparison on the TCGA-KIRC data
Thryonomys Fitzinger 1867
Creators: name: Woods, Charles A.
Publisher: name: Zenodo
Year: 1993
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Thryonomyidae
Thryonomys

description: Thryonomys Fitzinger, 1867. Sitzb. Akad. Wiss. Wien, 56(1):141. TYPE SPECIES: Aulacodus swinderianus Temminck, 1827. SYNONYMS: Aulacodus, Choeromys, Triaulacodus.
description: Published as part of Charles A. Woods, 1993, Order Rodentia - Suborder Hystricognathi, pp. 771-806 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on page 775, DOI: 10.5281/zenodo.7353083
description: {"references": ["Temminck, C. J. 1827 [1824] - 1841. Monographies de Mammalogie, ou description de quelques genres de mammiferes, dont les especes ont ete observees dans les differens musees de l'Europe. C. C. Vander Hoek, Leiden, 392 pp."]}
Additional file 1 of Leukocyte telomere length, allelic variations in related genes and risk of coronary heart disease in people with long-standing type 1 diabetes
Creators: name: Sanchez, Manuel
name: Kannengiesser, Caroline
name: Hoang, Sophie
name: Potier, Louis
name: Fumeron, Frédéric
name: Venteclef, Nicolas
name: Scheen, André
name: Gautier, Jean-François
name: Hadjadj, Samy
name: Marre, Michel
name: Roussel, Ronan
name: Mohammedi, Kamel
name: Velho, Gilberto
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1: Table S1. Baseline characteristics of GENEDIAB and GENESIS participants included in the present investigation. Table S2. Baseline characteristics of participants included or not in the LTL or the SNP studies. Table S3. SNPs in LTL-related genes genotyped in GENEDIAB and GENESIS participants. Table S4. Baseline characteristics of GENEDIAB participant by LTL tertiles of LTL distribution. Table S5. CHD risk during follow-up in the GENEDIAB cohort by baseline LTL with all-cause death as a competing risk. Figure S1. Flow chart of participants.
Strategy For Assessment Of Land And Complex Fields Type Analysis Through GIS In Bangladesh
Creators: name: Rumi, Yeasir Fathah
name: Prodhan, Uzzal Kumar
name: Hussain, Mohammed Ibrahim
name: Parvez, A. H. M. Shahariar
name: Hossain, Md. Ali
Publisher: name: arXiv
Year: 2013
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Bangladesh is an over populated developing country where crisis of food is a major issue, it faces different infrastructure problem in every sector. For Poverty Alleviation from the country we have to confirm cultivable land to increase the crop production for feeding the over population of the country. This paper focuses on the measurement of cultivable land for cultivation. The main purpose of this paper is to briefly describe how the GIS, Digital Mapping, Internet concepts and tools can effectively contribute in the modeling, analysis and visualization phases within an engineering or research project according to the crops by using object detection, object tracking and field mapping in Bangladesh. Through GIS mapping of the agricultural lands, the statistics can be made of how much land is cultivable and each year how much land we are losing. Mapping the cultivation land will tell us how much crop we have to import from other countries. Enabling real-time GIS analysis anytime, anywhere, the implementation of the GIS information to a wider aspect. Automation is the indicator of the modern civilizations. The system will benefit the food stock of the country according to the harvest. For this research we developed a new interactive system. The system will integrate with GIS project data in Google Earth, first finds highly accurate cluster images and partial images, obtains user feedback to merge or correct these digests, and then the supplementary visual analysis complete the partitioning of the data. This study was conducted at the software laboratory, Computer Science and Engineering department, Jahangirnagar University, Dhaka, Bangladesh in 2013.
description: 13 pages, 7 Figures
A cerebellar learning model that reproduces the behavior of vestibulo-ocular reflex adaptation in wild-type and knock-out mice
Creators: name: Clopath, Claudia
name: Badura, A.
name: De Zeeuw, C. I.
name: Brunel, N.
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Cerebellum
subject: Mice as laboratory animals
subject: Neuroplasticity
subject: Vestibulo-ocular reflex
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Medical sciences

description: The cerebellum is crucial for different types of motor learning. Established theories of cerebellar learning posit that the cerebellum learns by adjusting the weights of Parallel Fiber (PF) to Purkinje cells (PC) synapses, thanks to teaching signals provided by Climbing Fiber inputs. While these theories are consistent with a large body of experimental data, in particular on synaptic plasticity in PF to PC synapses, they cannot easily explain a growing body of experimental work, which seems to indicate a significant role of other sites of plasticity. Recent advances in the development of a large number in transgenic animals, as well as behavioral and electrophysiogical comparative studies between these animals and wild-type animals, have opened an unprecedented window into the mechanisms underlying learning in this structure. In particular, it has been shown that specific knock-outs are impaired selectively on difficult variants of the vestibulo-ocular reflex (VOR) adaptation task, one of the most studied cerebellar-dependent motor learning tasks. These impairments can occur even though the classical plasticity mechanisms are left untouched. These data pose significant new challenges for established models of cerebellar learning.
Mass Extinction And The Structure Of The Milky Way
Creators: name: Filipović, M. D.
name: Horner, J.
name: Crawford, E. J.
name: Tothill, N. F. H.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We use the most up to date Milky Way model and solar orbit data in order to test the hypothesis that the Sun's galactic spiral arm crossings cause mass extinction events on Earth. To do this, we created a new model of the Milky Way's spiral arms by combining a large quantity of data from several surveys. We then combined this model with a recently derived solution for the solar orbit to determine the timing of the Sun's historical passages through the Galaxy's spiral arms. Our new model was designed with a symmetrical appearance, with the major alteration being the addition of a spur at the far side of the Galaxy. A correlation was found between the times at which the Sun crosses the spiral arms and six known mass extinction events. Furthermore, we identify five additional historical mass extinction events that might be explained by the motion of the Sun around our Galaxy. These five additional significant drops in marine genera that we find include significant reductions in diversity at 415, 322, 300, 145 and 33 Myr ago. Our simulations indicate that the Sun has spent ~60% of its time passing through our Galaxy's various spiral arms. Also, we briefly discuss and combine previous work on the Galactic Habitable Zone with the new Milky Way model.
description: Accepted for publication in Serbian Astronomical Journal
title: Humoral signatures of MOG-antibody-associated disease track with age and disease activity
Creators: name: Spatola, Marianna
name: Chuquisana, Omar
name: Jung, Wonyeong
name: Lopez, Joseph A.
name: Wendel, Eva-Maria
name: Ramanathan, Sudarshini
name: Keller, Christian W.
name: Hahn, Tim
name: Meinl, Edgar
name: Reindl, Markus
name: Dale, Russell C.
name: Wiendl, Heinz
name: Lauffenburger, Douglas A.
name: Rostásy, Kevin
name: Brilot, Fabienne
name: Alter, Galit
name: Lünemann, Jan
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2023
Subjects: subject: 610 Medicine and health

description: Myelin oligodendrocyte glycoprotein (MOG)-antibody (Ab)-associated disease (MOGAD) is an inflammatory demyelinating disease of the CNS. Although MOG is encephalitogenic in different mammalian species, the mechanisms by which human MOG-specific Abs contribute to MOGAD are poorly understood. Here, we use a systems-level approach combined with high-dimensional characterization of Ab-associated immune features to deeply profile humoral immune responses in 123 patients with MOGAD. We show that age is a major determinant for MOG-antibody-related immune signatures. Unsupervised clustering additionally identifies two dominant immunological endophenotypes of MOGAD. The pro-inflammatory endophenotype characterized by increased binding affinities for activating Fcγ receptors (FcγRs), capacity to activate innate immune cells, and decreased frequencies of galactosylated and sialylated immunoglobulin G (IgG) glycovariants is associated with clinically active disease. Our data support the concept that FcγR-mediated effector functions control the pathogenicity of MOG-specific IgG and suggest that FcγR-targeting therapies should be explored for their therapeutic potential in MOGAD.
description: Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Thryonomys gregorianus
Creators: name: Woods, Charles A.
Publisher: name: Zenodo
Year: 1993
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Thryonomyidae
Thryonomys
Thryonomys gregorianus

description: Thryonomys gregorianus (Thomas, 1894). Ann. Mag. Nat. Hist., ser. 6, 13:202. TYPE LOCALITY: Kenya, Kiroyo, Luiji Reru River (00°35'S, 37°05'E). DISTRIBUTION: Cameroon, Central African Republic, Zaire, S Sudan, Ethiopia, Kenya, Uganda, Tanzania, Malawi, Zambia, Zimbabwe, Mozambique. STATUS: Common. SYNONYMS: camerunensis, harrisoni, logonensis, rutshuricus, sclateri. COMMENTS: See Misonne (1974:7).
description: Published as part of Charles A. Woods, 1993, Order Rodentia - Suborder Hystricognathi, pp. 771-806 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on page 775, DOI: 10.5281/zenodo.7353083
description: {"references": ["Misonne, X. 1974. Order Rodentia. Part 6. Pp. 1 - 39, in The mammals of Africa: An identification manual (J. Meester and H. W. Setzer, eds.). [issued 10 Sep 1974]. Smithsonian Institution Press, Washington, D. C., not continuously paginated."]}
Az egyes nemzetközi szervezetek reagálása a családon belüli erőszakra pandémia idején
Creators: name: Domokos, Andrea
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 489999
subject: Other law and legal studies not elsewhere classified

description: Az egyes nemzetközi szervezetek reagálása a családon belüli erőszakra pandémia idejénJogelméleti Szemle 2021, (3) 25-33. ISSN 1588-080X
Broken discrete and continuous symmetries in two dimensional spiral antiferromagnets
Creators: name: Mezio, A.
name: Sposetti, C. N.
name: Manuel, L. O.
name: Trumper, A. E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the occurrence of symmetry breakings, at zero and finite temperatures, in the J_1-J_3 antiferromagnetic Heisenberg model on the square lattice using Schwinger boson mean field theory. For spin-1/2 the ground state breaks always the SU(2) symmetry with a continuous quasi-critical transition at J_3/J_1=0.38, from Néel to spiral long range order, although local spin fluctuations considerations suggest an intermediate disordered regime around 0.35 < J_3/J_1 < 0.5, in qualitative agreement with recent numerical results. At low temperatures we find a Z_2 broken symmetry region with short range spiral order characterized by an Ising-like nematic order parameter that compares qualitatively well with classical Monte Carlo results. At intermediate temperatures the phase diagram shows regions with collinear short range orders: for J_3/J_1<1 Néel (π,π) correlations and for J_3/J_1>1 a novel phase consisting of four decoupled third neighbour sublattices with Néel (π,π) correlations in each one. We conclude that the effect of quantum and thermal fluctuations is to favour collinear correlations even in the strongly frustrated regime.
description: 17 pages, accepted for publication in Journal of Physics: condensed Matter
Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation
Creators: name: Muchir, Antoine
name: Kim, Young Jin
name: Reilly, Sarah A.
name: Wu, Wei
name: Choi, Jason C.
name: Worman, Howard J.
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Nuclear membranes
subject: Muscular dystrophy
subject: Muscular dystrophy--Genetic aspects
subject: Mitogen-activated protein kinases
subject: Medical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences

description: Background
Autosomal Emery-Dreifuss muscular dystrophy is caused by mutations in the lamin A/C gene (LMNA) encoding A-type nuclear lamins, intermediate filament proteins of the nuclear envelope. Classically, the disease manifests as scapulo-humeroperoneal muscle wasting and weakness, early joint contractures and dilated cardiomyopathy with conduction block; however, move variable skeletal muscle involvement can be present. Previously, we demonstrated increased activity of extracellular signal-regulated kinase (ERK) 1/2 in hearts of LmnaH222P/H222P mice, a model of autosomal Emery-Dreifuss muscular dystrophy, and that blocking its activation improved cardiac function. We therefore examined the role of ERK1/2 activity in skeletal muscle pathology.

Methods
Sections of skeletal muscle from LmnaH222P/H222P mice were stained with hematoxylin and eosin and histological analysis performed using light microscopy. ERK1/2 activity was assessed in mouse tissue and cultured cells by immunoblotting and real-time polymerase chain reaction to measure expression of downstream target genes. LmnaH222P/H222P mice were treated with selumetinib, which blocks mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 that activates ERK1/2, from 16 to 20 weeks of age to assess the effects of treatment on muscle histology, ERK1/2 activity and limb grip strength.

Results
We detected enhanced activation of ERK1/2 in skeletal muscle of LmnaH222P/H222P mice. Treatment with selumetinib ameliorated skeletal muscle histopathology and reduced serum creatine phosphokinase and aspartate aminotransferase activities. Selumetinib treatment also improved muscle function as assessed by in vivo grip strength testing.

Conclusions
Our results show that ERK1/2 plays a role in the development of skeletal muscle pathology in LmnaH222/H222P mice. They further provide the first evidence that a small molecule drug may be beneficial for skeletal muscle in autosomal Emery-Dreifuss muscular dystrophy.
Registro 5
Creators: name: López-González, Enrique
name: Bermejo, César
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Education

description: Registro centrado en las noticias resaltadas de las últimas semanas y las tecnologías que han salido que son interesantes desde el punto de vista de la asignatura y que pueden ser interesantes para el desarrollo de la práctica.
Thryonomys swinderianus
Creators: name: Woods, Charles A.
Publisher: name: Zenodo
Year: 1993
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Thryonomyidae
Thryonomys
Thryonomys swinderianus

description: Thryonomys swinderianus (Temminck, 1827). Monogr. Mamm., 1:248. TYPE LOCALITY: Sierra Leone. DISTRIBUTION: Africa south of the Sahara. SYNONYMS: calamophagus, raptorum, semipalmatus, variegatus.
description: Published as part of Charles A. Woods, 1993, Order Rodentia - Suborder Hystricognathi, pp. 771-806 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on page 775, DOI: 10.5281/zenodo.7353083
Godbillon-Vey classes of a family of regular foliations
Creators: name: Ida, Cristian
name: Popescu, Paul
Publisher: name: arXiv
Year: 2014
Subjects: subject: Geometric Topology (math.GT)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 57R15, 57R30, 57R25

description: The aim of the paper is to construct some Godbillon-Vey classes of a family of regular foliations, defined in the paper. These classes are cohomology classes on the manifold or on suitable open subsets. Some examples are also considered.
description: A new version with minor corrections
Additional file 1 of Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
Creators: name: Shim, Jin-Kyoung
name: Choi, Seonah
name: Yoon, Seon-Jin
name: Choi, Ran Joo
name: Park, Junseong
name: Lee, Eun Hee
name: Cho, Hye Joung
name: Lee, Suji
name: Teo, Wan-Yee
name: Moon, Ju Hyung
name: Kim, Hyun Sil
name: Kim, Eui Hyun
name: Cheong, Jae-Ho
name: Chang, Jong Hee
name: Yook, Jong In
name: Kang, Seok-Gu
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer

description: Additional file 1: Table S1. Clinicohistopathologic characteristics of the tumor-free cortex and GBM tissue. Table S2. Histopathologic characteristics of GBM tissues from which TSs were derived. Figure S1. Mitochondrial stress analysis showing decreased OCR in TS13-64 following etomoxir treatment. Figure S2. The sphere-forming capacity of GBM TSs cells were examined using the Extreme Limiting Dilution Assay (ELDA). TS cells were seeded in increasing order per well (1, 5, 10, 20, and 50 cells per well) in TS complete media with or without drugs in 96-well plates. The number of tumor spheres in each well was counted 7 days after plating. The online ELDA analysis tool was used ( http://bioinf.wehi.edu.au/software/elda ). Figure S3. Effects of etomoxir and TMZ combination treatment on gene expression profile as determined by RNA-sequencing. TS13-64 cells were treated with etomoxir and/or TMZ for 72 h, and RNA-sequencing was performed to determine the gene expression profiles. a Average linkage hierarchical clustering was achieved with Euclidean distance used as a distance metric for genes showing average expression in the top 30%. Expression was visualized as a heat map using GENE-E software. Among the DEGs between the control and combination groups, genes with b. upregulated and c. downregulated expression following combination therapy were functionally annotated, clustered, and visualized in an enrichment map. Each node represents a GO term with the size of the nodes indicating the statistical significance of over-representation. The kappa score connection is represented by an edge between two nodes. Clustered modules are represented by node colors, and the most important GO phrases for each module are shown with highlighted labels. Figure S4. Kaplan–Meier survival curves following etomoxir-alone, TMZ-alone, or etomoxir-TMZ combination treatment. a–c The etomoxir-only and combination groups had significantly improved survival compared to the control group, in contrast to the TMZ-only group. d–e The combination group exhibited improved survival compared to the etomoxir- or TMZ-only groups.
Erethizontidae Bonaparte 1845
Creators: name: Woods, Charles A.
Publisher: name: Zenodo
Year: 1993
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Erethizontidae

description: Family Erethizontidae Bonaparte, 1845. Cat. Meth. Mamm. Europe, p. 5. COMMENTS: Spelled Erithizontidae by Corbet and Hill (1980:189); but see comment under Erethizon. Extinct forms date to the Oligocene of South America. The genus Chaetomys is moved to Echimyidae based on its retention of the deciduous premolars and other dental features (see Patterson and Wood, 1982:394), although retained in Erethizontidae by Corbet and Hill (1991:200).
description: Published as part of Charles A. Woods, 1993, Order Rodentia - Suborder Hystricognathi, pp. 771-806 in Mammal Species of the World (2 nd Edition), Washington and London :Smithsonian Institution Press on page 775, DOI: 10.5281/zenodo.7353083
description: {"references": ["Corbet, G. B., and J. E. Hill. 1980. A world list of mammalian species. British Museum (Natural History), London, 226 pp.", "Patterson, B., and A. E. Wood. 1982. Rodents from the Deseadan Oligocene of Bolivia and the relationships of the Caviomorpha. Bulletin Museum of Comparative Zoology, 149: 371 - 543.", "Corbet, G. B., and J. E. Hill. 1991. A world list of mammalian species. Third ed. British Museum (Natural History) Publications, London, 243 pp."]}
Inhibition of p38 MAPK Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation
Creators: name: Liu, Liang
name: Rezvani, Hamid Reza
name: Back, Jung Ho
name: Hosseini, Mohsen
name: Tang, Xiuwei
name: Zhu, Yucui
name: Mahfouf, Walid
name: Raad, Houssam
name: Raji, Grace
name: Athar, Mohammad
name: Kim, Arianna
name: Bickers, David R.
Publisher: name: Columbia University
Year: 2014
Subjects: Mitogen-activated protein kinases
Carcinogenesis
Skin--Tumors
Oncology
Medical sciences
Cytology

description: p38 mitogen-activated protein kinases (MAPKs) respond to a wide range of extracellular stimuli. While the inhibition of p38 signaling is implicated in the impaired capacity to repair ultraviolet (UV)-induced DNA damage—a primary risk factor for human skin cancers—its mechanism of action in skin carcinogenesis remains unclear, as both anti-proliferative and survival functions have been previously described. In this study, we utilized cultured keratinocytes, murine tumorigenesis models, and human cutaneous squamous cell carcinoma (SCC) specimens to assess the effect of p38 in this regard. UV irradiation of normal human keratinocytes increased the expression of all four p38 isoforms (α/β/γ/δ); whereas irradiation of p53-deficient A431 keratinocytes derived from a human SCC selectively decreased p38α, without affecting other isoforms. p38α levels are decreased in the majority of human cutaneous SCCs assessed by tissue microarray, suggesting a tumor-suppressive effect of p38α in SCC pathogenesis. Genetic and pharmacological inhibition of p38α and in A431 cells increased cell proliferation, which was in turn associated with increases in NAPDH oxidase (NOX2) activity as well as intracellular reactive oxygen species (ROS). These changes led to enhanced invasiveness of A431 cells as assessed by the matrigel invasion assay. Chronic treatment of p53-/-/SKH-1 mice with the p38 inhibitor SB203580 accelerated UV-induced SCC carcinogenesis and increased the expression of NOX2. NOX2 knockdown suppressed the augmented growth of A431 xenografts treated with SB203580. These findings indicate that in the absence of p53, p38α deficiency drives SCC growth and progression that is associated with enhanced NOX2 expression and ROS formation.
Additional file 2 of Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
Creators: name: Shim, Jin-Kyoung
name: Choi, Seonah
name: Yoon, Seon-Jin
name: Choi, Ran Joo
name: Park, Junseong
name: Lee, Eun Hee
name: Cho, Hye Joung
name: Lee, Suji
name: Teo, Wan-Yee
name: Moon, Ju Hyung
name: Kim, Hyun Sil
name: Kim, Eui Hyun
name: Cheong, Jae-Ho
name: Chang, Jong Hee
name: Yook, Jong In
name: Kang, Seok-Gu
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer

description: Additional file 2: Figure S5. Original image indicating AMPKa, p-AMPKa, ACC2, CPT1 and GAPDH for Western blots of figure 3c. Figure S6. Original image indicating CD133, Nestin, SOX2, Msi-1 and GAPDH for Western blots of figure 4b. Figure S7. Original image indicating CD133, Nestin, SOX2, Msi-1 and GAPDH for Western blots of figure 4e.
Is the Universe Simpler than LCDM?
Creators: name: Walker, Matthew G.
name: Loeb, Abraham
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In the standard cosmological model, the Universe consists mainly of two invisible substances: vacuum energy with constant mass-density rho_v=Λ/(8pi G) (where Lambda is a `cosmological constant' originally proposed by Einstein and G is Newton's gravitational constant) and cold dark matter (CDM) with mass density that is currently rho_{DM,0}\sim 0.3 rho_v. This `LCDM' model has the virtue of simplicity, enabling straightforward calculation of the formation and evolution of cosmic structure against the backdrop of cosmic expansion. Here we review apparent discrepancies with observations on small galactic scales, which LCDM must attribute to complexity in the baryon physics of galaxy formation. Yet galaxies exhibit structural scaling relations that evoke simplicity, presenting a clear challenge for formation models. In particular, tracers of gravitational potentials dominated by dark matter show a correlation between orbital size, R, and velocity, V, that can be expressed most simply as a characteristic acceleration, a_{DM}\sim 1 km^2 s^{-2} pc^{-1} \approx 3 x 10^{-9} cm s^{-2} \approx 0.2c\sqrt{G rho_v}, perhaps motivating efforts to find a link between localized and global manifestations of the Universe's dark components.
description: replaced with accepted version (added two figures and some text)
Symmetric generalized binomial distributions
Creators: name: Bergeron, H.
name: Curado, E. M. F.
name: Gazeau, J. P.
name: Rodrigues, Ligia M. C. S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In two recent articles we have examined a generalization of the binomial distribution associated with a sequence of positive numbers, involving asymmetric expressions of probabilities that break the symmetry {\it win-loss}. We present in this article another generalization (always associated with a sequence of positive numbers) that preserves the symmetry {\it win-loss}. This approach is also based on generating functions and presents constraints of non-negativeness, similar to those encountered in our previous articles.
description: 23 pages, 2 figures
Lactobacillus crispatus Dominant Vaginal Microbiome Is Associated with Inhibitory Activity of Female Genital Tract Secretions against Escherichia coli
Creators: name: Ghartey, Jeny P.
name: Smith, Benjamin C.
name: Chen, Zigui
name: Buckley, Niall
name: Lo, Yungtai
name: Ratner, Adam Jonathan
name: Herold, Betsy C.
name: Burk, Robert D.
Publisher: name: Columbia University
Year: 2014
Subjects: subject: Generative organs, Female--Secretions
subject: Lactobacillus
subject: Escherichia coli
subject: Obstetrics
subject: Gynecology
subject: Microbiology
subject: FOS: Biological sciences

description: Objective:

Female genital tract secretions inhibit E. coli ex vivo and the activity may prevent colonization and provide a biomarker of a healthy microbiome. We hypothesized that high E. coli inhibitory activity would be associated with a Lactobacillus crispatus and/or jensenii dominant microbiome and differ from that of women with low inhibitory activity.

Study Design:

Vaginal swab cell pellets from 20 samples previously obtained in a cross-sectional study of near-term pregnant and non-pregnant healthy women were selected based on having high (>90% inhibition) or low (<20% inhibition) anti-E. coli activity. The V6 region of the 16S ribosomal RNA gene was amplified and sequenced using the Illumina HiSeq 2000 platform. Filtered culture supernatants from Lactobacillus crispatus, Lactobacillus iners, and Gardnerella vaginalis were also assayed for E. coli inhibitory activity.

Results:

Sixteen samples (10 with high and 6 with low activity) yielded evaluable microbiome data. There was no difference in the predominant microbiome species in pregnant compared to non-pregnant women (n = 8 each). However, there were significant differences between women with high compared to low E. coli inhibitory activity. High activity was associated with a predominance of L. crispatus (p<0.007) and culture supernatants from L. crispatus exhibited greater E. coli inhibitory activity compared to supernatants obtained from L. iners or G. vaginalis. Notably, the E. coli inhibitory activity varied among different strains of L. crispatus.

Conclusion:

Microbiome communities with abundant L. crispatus likely contribute to the E. coli inhibitory activity of vaginal secretions and efforts to promote this environment may prevent E. coli colonization and related sequelae including preterm birth.
Relativistic mean field plus exact pairing approach to open shell nuclei
Creators: name: Chen, Wei-Chia
name: Piekarewicz, J.
name: Volya, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Background: Pairing correlations play a critical role in determining numerous properties of open-shell nuclei. Traditionally, they are included in a mean-field description of atomic nuclei through the approximate Bardeen-Cooper-Schrieffer or Hartree-Fock-Bogoliubov formalism. Purpose: We propose a new hybrid ''relativistic-mean-field-plus-pairing'' approach in which pairing is treated exactly so the number of particles is conserved. To verify the reliability of the formalism, we apply it to the study of both ground-state properties and isoscalar monopole excitations of the Tin isotopes. Methods: Accurately-calibrated relativistic mean-field models supplemented by an exact treatment of pairing correlations are used to compute ground-state observables along the isotopic chain in Tin. In turn, ground-state densities are used as input to the calculation of giant monopole resonances through a constrained-relativistic approach. Results: We compute a variety of ground-state observables sensitive to pairing correlations as well as the evolution of giant monopole energies along the isotopic chain in Tin. Whereas ground-state properties are consistent with experiment, we find that pairing correlations have a minor effect on the giant monopole energies. Conclusions: A new mean-field-plus-pairing approach is introduced to compute properties of open-shell nuclei. The formalism provides an efficient and powerful alternative to the computation of both ground-state properties and monopole energies of open-shell nuclei. We find ground-state properties to be well reproduced in this approach. However, as many have concluded before us, we find that pairing correlations are unlikely to provide an answer to the question of ''why is Tin so soft?''
description: 13 pages, 4 figures
GENERAL CONCEPTS OF WESTERN AND EASTERN PHILOSOPHY, EDUCATION, AND CULTURE
Creators: name: Xayridinov, Abbosxon
Publisher: name: Zenodo
Year: 2025

description: This articlе analyzеs thе main fеaturеs of Еastеrn and Wеstеrn philosophy, еducational systеms and culturеs. Whilе Еastеrn philosophy is focusеd on moral and spiritual dеvеlopmеnt, Wеstеrn philosophy is basеd on sciеntific mеthodology and critical thinking. It also analyzеs approachеs in thе еducational systеm, cultural valuеs and thеir intеraction. It еxaminеs how thе intеgration of Еastеrn and Wеstеrn culturе and philosophy in thе contеxt of modеrn globalization affеcts human dеvеlopmеnt.
Additional file 1 of The baroreceptor reflex brought to life outside the classroom – an e-learning based asynchronous laboratory class using a non-supervised modified Active Standing Test
Creators: name: Heinrich, Tobias
name: Sehner, Susanne
name: Wageringel, Isabel
name: Ehmke, Heimo
name: Schwoerer, Alexander Peter
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1. Instructions and experimental protocol. Stepwise instructions to the mAST and experimental protocol table as provided for the students (translated from German).
Domestic Animal Hosts Strongly Influence Human-Feeding Rates of the Chagas Disease Vector Triatoma infestans in Argentina
Creators: name: Gürtler, Ricardo E.
name: Cecere, María C.
name: Vázquez-Prokopec, Gonzalo M.
name: Ceballos, Leonardo A.
name: Gurevitz, Juan M.
name: Del Pilar Fernández, María
name: Kitron, Uriel
name: Cohen, Joel E.
Publisher: name: Columbia University
Year: 2014
Subjects: Conenoses
Chagas' disease--Transmission
Domestic animals
Parasitology
Public health

description: Background:

The host species composition in a household and their relative availability affect the host-feeding choices of blood-sucking insects and parasite transmission risks. We investigated four hypotheses regarding factors that affect blood-feeding rates, proportion of human-fed bugs (human blood index), and daily human-feeding rates of Triatoma infestans, the main vector of Chagas disease.

Methods:

A cross-sectional survey collected triatomines in human sleeping quarters (domiciles) of 49 of 270 rural houses in northwestern Argentina. We developed an improved way of estimating the human-feeding rate of domestic T. infestans populations. We fitted generalized linear mixed-effects models to a global model with six explanatory variables (chicken blood index, dog blood index, bug stage, numbers of human residents, bug abundance, and maximum temperature during the night preceding bug catch) and three response variables (daily blood-feeding rate, human blood index, and daily human-feeding rate). Coefficients were estimated via multimodel inference with model averaging.

Findings:

Median blood-feeding intervals per late-stage bug were 4.1 days, with large variations among households. The main bloodmeal sources were humans (68%), chickens (22%), and dogs (9%). Blood-feeding rates decreased with increases in the chicken blood index. Both the human blood index and daily human-feeding rate decreased substantially with increasing proportions of chicken- or dog-fed bugs, or the presence of chickens indoors. Improved calculations estimated the mean daily human-feeding rate per late-stage bug at 0.231 (95% confidence interval, 0.157–0.305).

Conclusions and Significance:

Based on the changing availability of chickens in domiciles during spring-summer and the much larger infectivity of dogs compared with humans, we infer that the net effects of chickens in the presence of transmission-competent hosts may be more adequately described by zoopotentiation than by zooprophylaxis. Domestic animals in domiciles profoundly affect the host-feeding choices, human-vector contact rates and parasite transmission predicted by a model based on these estimates.
Mars Encounters cause fresh surfaces on some near-Earth asteroids
Creators: name: DeMeo, Francesca E.
name: Binzel, Richard P.
name: Lockhart, Matthew
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: All airless bodies are subject to the space environment, and spectral differences between asteroids and meteorites suggest many asteroids become weathered on very short (<1My) timescales. The spectra of some asteroids, particularly Q-types, indicate surfaces that appear young and fresh, implying they have been recently been exposed. Previous work found that Earth encounters were the dominant freshening mechanism and could be responsible for all near-Earth object (NEO) Q-types. In this work we increase the known NEO Q-type sample of by a factor of three. We present the orbital distributions of 64 Q-type near-Earth asteroids, and seek to determine the dominant mechanisms for refreshing their surfaces. Our sample reveals two important results: i) the relatively steady fraction of Q-types with increasing semi-major axis and ii) the existence of Q-type near-Earth asteroids with Minimum Orbit Intersection Distances (MOID) that do not have orbit solutions that cross Earth. Both of these are evidence that Earth-crossing is not the only scenario by which NEO Q-types are freshened. The high Earth-MOID asteroids represent 10% of the Q-type population and all are in Amor orbits. While surface refreshing could also be caused by Main Belt collisions or mass shedding from YORP spinup, all high Earth-MOID Q-types have the possibility of encounters with Mars indicating Mars could be responsible for a significant fraction of NEOs with fresh surfaces.
description: Accepted for publication in Icarus -- 14 pages, 8 figures, 1 table, 2 appendices