cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Strong Coupling Quantum Thermodynamics far away from Equilibrium: Non-Markovian Transient Quantum Heat and Work
Creators: name: Huang, Wei-Ming
name: Zhang, Wei-Min
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In this paper, we investigate the strong coupling quantum thermodynamics of the hybrid quantum system far away from equilibrium. The strong coupling hybrid system consists of a cavity and a spin ensemble of the NV centers in diamond under external driving that has been realized experimentally. We apply the renormalization theory of quantum thermodynamics we developed recently to study the transient quantum heat and work in this hybrid system. We find that the dissipation and fluctuation dynamics of the system induce the transient quantum heat current which involve the significant non-Markovian effects. On the other hand, the energy renormalization and the external driving induce the quantum work power. The driving-induced work power also manifests non-Markovian effects due to the feedback of non-Markovian dynamics of the cavity due to its strong coupling with the spin ensemble.
description: 10 pages, 9 figures
A Robust Method for Transcript Quantification with RNA-Seq Data
Creators: name: Liu, Yufeng
name: Hu, Yin
name: Prins, Jan F.
name: Chiang, Derek Y.
name: Jones, Corbin D.
name: MacLeod, James N.
name: Huang, Yan
name: Liu, Jinze
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The advent of high throughput RNA-seq technology allows deep sampling of the transcriptome, making it possible to characterize both the diversity and the abundance of transcript isoforms. Accurate abundance estimation or transcript quantification of isoforms is critical for downstream differential analysis (e.g., healthy vs. diseased cells) but remains a challenging problem for several reasons. First, while various types of algorithms have been developed for abundance estimation, short reads often do not uniquely identify the transcript isoforms from which they were sampled. As a result, the quantification problem may not be identifiable, i.e., lacks a unique transcript solution even if the read maps uniquely to the reference genome. In this article, we develop a general linear model for transcript quantification that leverages reads spanning multiple splice junctions to ameliorate identifiability. Second, RNA-seq reads sampled from the transcriptome exhibit unknown position-specific and sequence-specific biases. We extend our method to simultaneously learn bias parameters during transcript quantification to improve accuracy. Third, transcript quantification is often provided with a candidate set of isoforms, not all of which are likely to be significantly expressed in a given tissue type or condition. By resolving the linear system with LASSO, our approach can infer an accurate set of dominantly expressed transcripts while existing methods tend to assign positive expression to every candidate isoform. Using simulated RNA-seq datasets, our method demonstrated better quantification accuracy and the inference of dominant set of transcripts than existing methods. The application of our method on real data experimentally demonstrated that transcript quantification is effective for differential analysis of transcriptomes.
Polyakov loop, gluon mass, gluon condensate and its asymmetry near deconfinement
Creators: name: Dudal, D.
name: van Egmond, D. M.
name: Reinosa, U.
name: Vercauteren, D.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a BRST invariant generalization of the "massive background Landau gauge", resembling the original Curci-Ferrari model that saw a revived interest due to its phenomenological success in modeling infrared Yang-Mills dynamics, including that of the phase transition. Unlike the Curci-Ferrari model, however, the mass parameter is no longer a phenomenological input but it enters as a result of dimensional transmutation via a BRST invariant dimension two gluon condensate. The associated renormalization constant is dealt with using Zimmermann's reduction of constants program which fixes the value of the mass parameter to values close to those obtained within the Curci-Ferrari approach. Using a self-consistent background field, we can include the Polyakov loop and probe the deconfinement transition, including its interplay with the condensate and its electric-magnetic asymmetry. We report a continuous phase transition at Tc ~ 0.230 GeV in the SU(2) case and a first order one at Tc ~ 0.164 GeV in the SU(3) case, values which are again rather close to those obtained within the Curci-Ferrari model at one-loop order.
description: 31 pages, 12 figures
Light trajectory and shadow shape in the rotating naked singularity
Creators: name: Patel, Vishva
name: Tahelyani, Divya
name: Joshi, Ashok B.
name: Dey, Dipanjan
name: Joshi, Pankaj S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, we investigate the light trajectories and shadow properties in the rotating version of null naked singularity (NNS) spacetime which is derived using the Newman- Janis algorithm without complexification method. We discuss some of the geometrical properties and causal structure of Rotating Naked Singularity (RNS) spacetime. The gravitational lensing in a rotating naked singularity is analyzed, and the results are compared to those of a Kerr black hole. In the case of a Kerr black hole, the photon sphere exists for both prograde and retrograde photon orbits, whereas for RNS, the photon sphere exists only for retrograde photon orbits. As a result, the naked singularity projects an arc-shaped shadow that differs from the contour-shaped shadow cast by a Kerr black hole.
description: 12 pages, 4 figures
Trypsin-ligand binding free energies from explicit and implicit solvent simulations with polarizable potential
Creators: name: Ren, Pengyu
name: Li, Guohui
name: Schnieders, Michael J.
name: Duke, Robert E.
name: Jiao, Dian
name: Zhang, Jiajing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: We have calculated the binding free energies of a series of benzamidine-like inhibitors to trypsin with a polarizable force field using both explicit and implicit solvent approaches. Free energy perturbation has been performed for the ligands in bulk water and in protein complex with molecular dynamics simulations. The calculated binding free energies are well within the accuracy of experimental measurement and the direction of change is predicted correctly in call cases. We analyzed the molecular dipole moments of the ligands in gas, water and protein environments. Neither binding affinity nor ligand solvation free energy in bulk water shows much dependence on the molecular dipole moments of the ligands. Substitution of the aromatic or the charged group in the ligand results in considerable change in the solvation energy in bulk water and protein whereas the binding affinity varies insignificantly due to cancellation. The effect of chemical modification on ligand charge distribution is mostly local. Replacing benzene with diazine has minimal impact on the atomic multipoles at the amidinium group. We have also utilized an implicit solvent based end-state approach to evaluate the binding free energies of these inhibitors. In this approach, the polarizable multipole model combined with Poisson-Boltzmann/surface area (PMPB/SA) provides the electrostatic interaction energy and the polar solvation free energy. Overall the relative binding free energies obtained from the PMPB/SA model are in good agreement with the experimental data.
Ramsey Scheme Applied to String Theoretical Processes
Creators: name: Wani, Salman Sajad
name: Shabir, Arshid
name: Faizal, Mir
name: Rubab, Seemin
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this letter, we analyze the evolution of physical quantities due to the interaction of strings with background fields. We will obtain the characteristic function for such a string theoretical process. This will be done by generalizing the Ramsey scheme to world-sheet, and using it to obtain the information about the evolution of quantity in a string theoretical process, without making two-point measurements. We will also use the characteristic function to obtain the average of the difference between the initial and final values of such a quantity. Finally, using the characteristic function, we calculate fisher information for the difference of such a quantity.
description: Accepted for publication in EPL
Combined Administration of Oxycodone/Naloxone in Chronic Osteo-Articular Diseases Pain Therapy
Creators: name: Palomba, Rosa
name: Miralto, Federica
name: Vinciguerra, Annamaria
name: Salvato, Fabiana
name: Vaccarella, Anna
Publisher: name: Universita' degli Studi di Salerno
Year: 2014
Subjects: Oxycodone/Naloxone
Chronic pain
Chronic osteo-articular diseases

description: The aim of this study is the analysis of the beneficial impact of using opioid receptor antagonist associated to opioid analgesic on the quality of life in patients suffering from chronic non-cancer pain. We recruited 60 patients suffering from osteo-articular diseases who were randomized into two groups of treatment. The group A was treated with the association of opioid receptor antagonist and opioid agonist, represented by Oxycodone. The group B was treated with the opioid analgesics Oxycodone, transdermal Fentanil, and Hidromorphone, without the opioid antagonist. The end-points assessed were the duration of titration, the average reached dosage, the duration of the stability of dosage and the opioid–induced constipation (OIC) using the BFI.
Galaxy populations in the Hydra I cluster from the VEGAS survey II. The ultra-diffuse galaxy population
Creators: name: La Marca, Antonio
name: Iodice, Enrichetta
name: Cantiello, Michele
name: Forbes, Duncan A.
name: Rejkuba, Marina
name: Hilker, Michael
name: Arnaboldi, Magda
name: Greggio, Laura
name: Spiniello, Chiara
name: Mieske, Steffen
name: Venhola, Aku
name: Spavone, Marilena
name: D'Ago, Giuseppe
name: Raj, Maria Angela
name: Ragusa, Rossella
name: Mirabile, Marco
name: Rampazzo, Roberto
name: Peletier, Reynier
name: Paolillo, Maurizio
name: Challapa, Nelvy Choque
name: Schipani, Pietro
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: In this work, we extend the catalog of low-surface brightness (LSB) galaxies, including Ultra-Diffuse Galaxy (UDG) candidates, within $\approx 0.4R_{vir}$ of the Hydra I cluster of galaxies, based on deep images from the VST Early-type GAlaxy Survey (VEGAS). The new galaxies are found by applying an automatic detection tool and carrying out additional visual inspections of $g$ and $r$ band images. This led to the detection of 11 UDGs and 8 more LSB galaxies. For all of them, the cluster membership has been assessed using the color-magnitude relation derived for early-type giant and dwarf galaxies in Hydra I. The UDGs and new LSB galaxies found in Hydra I span a wide range of central surface brightness ($22.7 \lesssim μ_{0,g} \lesssim 26.5$ mag/arcsec$^2$), effective radius ($0.6 \lesssim R_e \lesssim 4.0$ kpc) and color ($0.4 \leq g-r \leq 0.9$ mag), and have stellar masses in the range $\sim 5\times 10^6 - 2\times 10^8$M$_{\odot}$. The 2D projected distribution of both galaxy types is similar to the spatial distribution of dwarf galaxies, with over-densities in the cluster core and north of the cluster centre. They have similar color distribution and comparable stellar masses to the red dwarf galaxies. Based on photometric selection, we identify a total of 9 globular cluster candidates associated to the UDGs and 4 to the LSB galaxies, with the highest number of candidates in an individual UDG being three. We find that there are no relevant differences between dwarfs, LSB galaxies and UDGs: the structural parameters (that is surface brightness, size, colors, n-index) and GCs content of the three classes have similar properties and trends. This finding is consistent with UDGs being the extreme LSB tail of the size-luminosity distribution of dwarfs in this environment.
description: Accepted for publication in A&A. 30 pages, 22 figures
CMB lensing from Planck PR4 maps
Creators: name: Carron, Julien
name: Mirmelstein, Mark
name: Lewis, Antony
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We reconstruct the Cosmic Microwave Background (CMB) lensing potential on the latest Planck CMB PR4 (NPIPE) maps, which include slightly more data than the 2018 PR3 release, and implement quadratic estimators using more optimal filtering. We increase the reconstruction signal to noise by almost $20\%$, constraining the amplitude of the CMB-marginalized lensing power spectrum in units of the Planck 2018 best-fit to $1.004 \pm 0.024$ ($68\%$ limits), which is the tightest constraint on the CMB lensing power spectrum to date. For a base $Λ$CDM cosmology we find $σ_8 Ω_m^{0.25} = 0.599\pm 0.016$ from CMB lensing alone in combination with weak priors and element abundance observations. Combination with baryon acoustic oscillation data gives tight $68\%$ constraints on individual $Λ$CDM parameters $σ_8 = 0.814\pm 0.016$, $H_0 = 68.1^{+1.0}_{-1.1}$km s$^{-1}$ Mpc$^{-1}$, $Ω_m = 0.313^{+0.014}_{-0.016}$. Planck polarized maps alone now constrain the lensing power to $7\%$.
description: 15 pages, 9 figures, 4 tables. Matches version accepted for publication
Full Investigation on the Dynamics of Power-Law Kinetic Quintessence
Creators: name: Fang, Wei
name: Tu, Hong
name: Li, Ying
name: Huang, Jiasheng
name: Shu, Chenggang
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We give a full investigation on the dynamics of power-law kinetic quintessence $L(X, ϕ)=V(ϕ)(-X+X^2)$ by considering the potential related parameter $Γ$($=\frac{V V''}{V'^2}$) as a function of another potential parameter $λ$($=\frac{V'}{κV^{3/2}}$), which correspondingly extends the analysis of the dynamical system of our universe from two-dimension to three-dimension. Beside the critical points found in previous papers, we find a new de-Sitter-like dominant attractor(\textit{cp$6$}) and give its stable condition using the center manifold theorem. For the dark energy dominant solution(\textit{cp$6$} and \textit{cp$7$}), it could be distinguished from canonical quintessence and tachyon models since the sound speed $c_s^2=0$ or $c_s^2\ll 1$. For the scaling solution (\textit{cp$8$}), it is very interesting that the sound speed $c_s^2=1/5$ while it behaves as ordinary matter. We therefore point out that the power-law kinetic quintessence should have different signatures on cold dark matter power spectrum and cosmic microwave background both at early time when this scalar field is an early dark energy with $Ω_ϕ$ being non-negligible at high redshift and at late time when it drives the accelerating expansion. We even do not know whether there are any degeneracies of the impacts between these two epoches. They are expected to be investigated in future.
description: 17 pages, 4 figures, accepted by Physical Review D, in press
Decays $h\to e_ae_b$, $e_b\to e_aγ$, and $(g-2)_{e,μ}$ in a 3-3-1 model with inverse seesaw neutrinos
Creators: name: Hong, T. T.
name: Nha, N. H. T.
name: Nguyen, T. Phong
name: Phuong, L. T. T.
name: Hue, L. T.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We will show that the 3-3-1 model with new heavy right handed neutrinos as $SU(3)_L$ singlets can explain simultaneously the lepton flavor violating decays of the SM-like Higgs boson, charged lepton flavor violating decays $e_b\rightarrow e_aγ$, and the electron $(g-2)_e$ anomalies under recent experimental data. The discrepancy of $(g-2)_μ$ predicted by the model under consideration and that of the standard model can reach $10^{-9}$. The decay rates of the standard model-like Higgs boson $h\to τe, τμ$ can reach the values of $\mathcal{O}(10^{-4})$.
description: 35 pages, new references were added, numerical investigations were changed, version accepted for publication in PTEP
Atomic forces for geometry-dependent point multipole and Gaussian multipole models
Creators: name: Darden, Thomas
name: Pedersen, Lee G.
name: Perera, Lalith
name: Elking, Dennis M.
name: Duke, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: In standard treatments of atomic multipole models, interaction energies, total molecular forces, and total molecular torques are given for multipolar interactions between rigid molecules. However, if the molecules are assumed to be flexible, two additional multipolar atomic forces arise due to 1) the transfer of torque between neighboring atoms, and 2) the dependence of multipole moment on internal geometry (bond lengths, bond angles, etc.) for geometry-dependent multipole models. In the current study, atomic force expressions for geometry-dependent multipoles are presented for use in simulations of flexible molecules. The atomic forces are derived by first proposing a new general expression for Wigner function derivatives ∂Dlm′m/∂Ω. The force equations can be applied to electrostatic models based on atomic point multipoles or Gaussian multipole charge density. Hydrogen bonded dimers are used to test the inter-molecular electrostatic energies and atomic forces calculated by geometry-dependent multipoles fit to the ab initio electrostatic potential (ESP). The electrostatic energies and forces are compared to their reference ab initio values. It is shown that both static and geometry-dependent multipole models are able to reproduce total molecular forces and torques with respect to ab initio, while geometry-dependent multipoles are needed to reproduce ab initio atomic forces. The expressions for atomic force can be used in simulations of flexible molecules with atomic multipoles. In addition, the results presented in this work should lead to further development of next generation force fields composed of geometry-dependent multipole models.
Mathematical Analysis of Dairy Farming
Creators: name: Dr. Vinay Pandit
name: Dr. Swati Desai
Publisher: name: Zenodo
Year: 2022
Subjects: Regression, Correlation, Nutritional food, A2 Milk

description: Abstract: Mathematics is the queen of science. The Application areas of Mathematics are of utmost importance. In this research article, the researcher has tried to study the correlational between the dependant variable fat content is the A2 milk of Indigenous cows of Various breeds. The current study highlights the importance of Nutritional food provided to the cows with green and dry fodder. The results state that there is a strong positive correlation between the nutritional fodder given to cows per day and the quality of Milk in terms of Fat content. The result was significance at 95 % confidence. Further using simple regression Ŷ = -0.7337 + 1.2323X the researcher has found out that the impact of nutritional fodder on quality of Milk in terms of Fat content. This accuracy level of this equation was 0.4376%. Also, this equation is significant at 5% LOS as 0.001491
Yaygın Anksiyete Bozukluğu ve Bilişsel Davranışçı Terapi Üzerine Sistematik Derleme
Creators: name: KARAEL, Buse
name: KARAAZİZ, Meryem
Publisher: name: Zenodo
Year: 2024

description: Bu derleme çalışmasının amacı yaygın anksiyete bozukluğu yaşayan bireylerde bilişsel davranışçı terapisinin kullanımını incelemektir. Yapılan bu çalışmada sistematik derleme yöntemi kullanılmış olup saha çalışması ya da herhangi bir ölçek kullanılmamıştır. Sadece İngilizce dilinde ele alınan çalışmalar 2009-2018 yılları arasındadır. Bu çalışmalar randomize kontrollü çalışmalardan oluşmaktadır. Bu derleme çalışması Şubat 2024 ve Mayıs 2024 olmak üzere iki aşamada gerçekleşmiştir. Yapılan literatür taraması sonucunda 6 çalışma ele alınmıştır. Ele alınan bu 6 çalışma sonucunda BDT’nin terapiye uyumu arttırıcı ve iyileşmeyi hızlandıran bir terapi yöntemi ve kısa süre içerisinde sonuca ulaşabilme yönünden etkin bir yöntem olduğu görülmüştür. YAB yaşayan bireylerde BDT terapisi uygulandıktan sonra belirtilerin büyük oranda azaldığı ve ortadan kaybolduğu bulunmuştur. Bu sebeple de YAB tedavisinde BDT terapisi etkili bir yöntemdir.
Observation of Density-Induced Tunneling
Creators: name: Jürgensen, Ole
name: Meinert, Florian
name: Mark, Manfred J.
name: Nägerl, Hanns-Christoph
name: Lühmann, Dirk-Sören
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We study the dynamics of bosonic atoms in a tilted one-dimensional optical lattice and report on the first direct observation of density-induced tunneling. We show that the interaction affects the time evolution of the doublon oscillation via density-induced tunneling and pinpoint its density- and interaction-dependence. The experimental data for different lattice depths are in good agreement with our theoretical model. Furthermore, resonances caused by second-order tunneling processes are studied, where the density-induced tunneling breaks the symmetric behavior for attractive and repulsive interactions predicted by the Hubbard model.
description: Including supplementary material
A finite field method for calculating molecular polarizability tensors for arbitrary multipole rank
Creators: name: Elking, Dennis M.
name: Darden, Thomas
name: Pedersen, Lee G.
name: Duke, Robert
name: Perera, Lalith
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: A finite field method for calculating spherical tensor molecular polarizability tensors αlm;l′m′ = ∂Δlm/∂ϕl′m′* by numerical derivatives of induced molecular multipole Δlm with respect to gradients of electrostatic potential ϕl′m′* is described for arbitrary multipole ranks l and l′. Inter-conversion formulae for transforming multipole moments and polarizability tensors between spherical and traceless Cartesian tensor conventions are derived. As an example, molecular polarizability tensors up to the hexadecapole-hexadecapole level are calculated for water at the HF, B3LYP, MP2, and CCSD levels. In addition, inter-molecular electrostatic and polarization energies calculated by molecular multipoles and polarizability tensors are compared to ab initio reference values calculated by the Reduced Variation Space (RVS) method for several randomly oriented small molecule dimers separated by a large distance. It is discussed how higher order molecular polarizability tensors can be used as a tool for testing and developing new polarization models for future force fields.
Performance of a Small Array of Imaging Air Cherenkov Telescopes sited in Australia
Creators: name: Lee, Simon
name: Einecke, Sabrina
name: Rowell, Gavin
name: Balazs, Csaba
name: Bellido, Jose A.
name: Dai, Shi
name: Elsässer, Dominik
name: Filipović, Miroslav
name: Harvey, Violet M.
name: McGee, Padric
name: Rhode, Wolfgang
name: Tingay, Steven
name: White, Martin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: As TeV gamma-ray astronomy progresses into the era of the Cherenkov Telescope Array (CTA), there is a desire for the capacity to instantaneously follow up on transient phenomena and continuously monitor gamma-ray flux at energies above $10^{12}$ eV. To this end, a worldwide network of Imaging Air Cherenkov Telescopes (IACTs) is required to provide triggers for CTA observations and complementary continuous monitoring. An IACT array sited in Australia would contribute significant coverage of the Southern Hemisphere sky. Here, we investigate the suitability of a small IACT array and how different design factors influence its performance. Monte Carlo simulations were produced based on the Small-Sized Telescope (SST) and Medium-Sized Telescope (MST) designs from CTA. Angular resolution improved with larger baseline distances up to 277m between telescopes, and energy thresholds were lower at 1000m altitude than at 0m. The $\sim$300 GeV energy threshold of MSTs proved more suitable for observing transients than the $\sim$1.2 TeV threshold of SSTs. An array of four MSTs at 1000m was estimated to give a 5.7$σ$ detection of an RS Ophiuchi-like nova eruption from a 4-hour observation. We conclude that an array of four MST-class IACTs at an Australian site would ideally complement the capabilities of CTA.
description: 10 pages, 13 figures, 2 tables, accepted for publication in PASA
Assessment of free energy predictors for ligand binding to a methyllysine histone code reader
Creators: name: Gao, Cen
name: Herold, J. Martin
name: Kireev, Dmitri
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Methyllysine histone code readers constitute a new promising group of potential drug targets. For instance, L3MBTL1, a Malignant Brain Tumor (MBT) protein, selectively binds mono- and di-methyllysine epigenetic marks (KMe, KMe2) that eventually results in the negative regulation of multiple genes through the E2F/Rb oncogenic pathway. There is a pressing need in potent and selective small-molecule probes that would enable further target validation and might become therapeutic leads. Such an endeavor would require efficient tools to assess the free energy of protein-ligand binding. However, due to an unparalleled function of the MBT binding pocket (i.e. selective binding to KMe/KMe2) and because of its distinctive structure representing a small aromatic “cage”, an accurate assessment of its binding affinity to a ligand appears to be a challenging task. Here, we report a comparative analysis of computationally affordable affinity predictors applied to a set of seven small-molecule ligands interacting with L3MBTL1. The analysis deals with novel ligands and targets, but applies widespread computational approaches and intuitive comparison metrics that makes this study compatible with and incremental to earlier large scale accounts on the efficiency of affinity predictors. Ultimately, this study has revealed three top performers, far ahead of the other techniques, including two scoring functions, PMF04 and PLP, along with a simulation-based method Molecular Mechanics Poisson-Boltzmann/Surface Area (MM-PB/SA). We discuss why some methods may perform better than others on this target class, the limits of their application, as well as how the efficiency of the most CPU-demanding techniques could be optimized.
An analysis of polynomial chaos approximations for modeling single-fluid-phase flow in porous medium systems
Creators: name: Miller, C.T.
name: Rupert, C.P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: We examine a variety of polynomial-chaos-motivated approximations to a stochastic form of a steady state groundwater flow model. We consider approaches for truncating the infinite dimensional problem and producing decoupled systems. We discuss conditions under which such decoupling is possible and show that to generalize the known decoupling by numerical cubature, it would be necessary to find new multivariate cubature rules. Finally, we use the acceleration of Monte Carlo to compare the quality of polynomial models obtained for all approaches and find that in general the methods considered are more efficient than Monte Carlo for the relatively small domains considered in this work. A curse of dimensionality in the series expansion of the log-normal stochastic random field used to represent hydraulic conductivity provides a significant impediment to efficient approximations for large domains for all methods considered in this work, other than the Monte Carlo method.
A one-dimensional liquid of fermions with tunable spin
Creators: name: Pagano, Guido
name: Mancini, Marco
name: Cappellini, Giacomo
name: Lombardi, Pietro
name: Schäfer, Florian
name: Hu, Hui
name: Liu, Xia-Ji
name: Catani, Jacopo
name: Sias, Carlo
name: Inguscio, Massimo
name: Fallani, Leonardo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Correlations in systems with spin degree of freedom are at the heart of fundamental phenomena, ranging from magnetism to superconductivity. The effects of correlations depend strongly on dimensionality, a striking example being one-dimensional (1D) electronic systems, extensively studied theoretically over the past fifty years. However, the experimental investigation of the role of spin multiplicity in 1D fermions - and especially for more than two spin components - is still lacking. Here we report on the realization of 1D, strongly-correlated liquids of ultracold fermions interacting repulsively within SU(N) symmetry, with a tunable number N of spin components. We observe that static and dynamic properties of the system deviate from those of ideal fermions and, for N>2, from those of a spin-1/2 Luttinger liquid. In the large-N limit, the system exhibits properties of a bosonic spinless liquid. Our results provide a testing ground for many-body theories and may lead to the observation of fundamental 1D effects.
description: 9 pages (including Supplementary Information), 4 figures
Continuum-kinetic-microscopic model of lung clearance due to core-annular fluid entrainment
Creators: name: Mitran, Sorin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The human lung is protected against aspirated infectious and toxic agents by a thin liquid layer lining the interior of the airways. This airway surface liquid is a bilayer composed of a viscoelastic mucus layer supported by a fluid film known as the periciliary liquid. The viscoelastic behavior of the mucus layer is principally due to long-chain polymers known as mucins. The airway surface liquid is cleared from the lung by ciliary transport, surface tension gradients, and airflow shear forces. This work presents a multiscale model of the effect of airflow shear forces, as exerted by tidal breathing and cough, upon clearance. The composition of the mucus layer is complex and variable in time. To avoid the restrictions imposed by adopting a viscoelastic flow model of limited validity, a multiscale computational model is introduced in which the continuum-level properties of the airway surface liquid are determined by microscopic simulation of long-chain polymers. A bridge between microscopic and continuum levels is constructed through a kinetic-level probability density function describing polymer chain configurations. The overall multiscale framework is especially suited to biological problems due to the flexibility afforded in specifying microscopic constituents, and examining the effects of various constituents upon overall mucus transport at the continuum scale.
A fully resolved active musculo-mechanical model for esophageal transport
Creators: name: Patankar, Neelesh A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multilayered muscular tube. This process involves interactions between the bolus, the esophagus, and the neurally coordinated activation of the esophageal muscles. In this work, we use an immersed boundary (IB) approach to simulate peristaltic transport in the esophagus. The bolus is treated as a viscous fluid that is actively transported by the muscular esophagus, and the esophagus is modeled as an actively contracting, fiber-reinforced tube. Before considering the full model of the esophagus, however, we first consider a standard benchmark problem of flow past a cylinder. Next a simplified version of our model is verified by comparison to an analytic solution to the tube dilation problem. Finally, three different complex models of the multi-layered esophagus, which differ in their activation patterns and the layouts of the mucosal layers, are extensively tested. To our knowledge, these simulations are the first of their kind to incorporate the bolus, the multi-layered esophagus tube, and muscle activation into an integrated model. Consistent with experimental observations, our simulations capture the pressure peak generated by the muscle activation pulse that travels along the bolus tail. These fully resolved simulations provide new insights into roles of the mucosal layers during bolus transport. In addition, the information on pressure and the kinematics of the esophageal wall resulting from the coordination of muscle activation is provided, which may help relate clinical data from manometry and ultrasound images to the underlying esophageal motor function.
Dikkat Eksikliği ve Hiperaktivite ve Oyun Terapisi Üzerine Derleme
Creators: name: AKOĞLU, Yağmur
name: KARAAZİZ, Meryem
Publisher: name: Zenodo
Year: 2024

description: Bu derleme çalışmasının amacı DEHB sahip bireylerde Oyun terapisinin nasıl kullanıldığını incelemektir. Yapılan bu çalışmada derleme yöntemi kullanılmış olup saha çalışması ya da herhangi bir ölçek kullanılmamıştır. İngilizce Türkçe dilinde ele alınan çalışmalar 2000-2022 yılları arasındadır. Bu çalışmalar araştırma makalelerinden oluşmaktadır. Bu derleme çalışması Şubat, 2024 ve Mayıs, 2024 olmak üzere iki aşamada gerçekleşmiştir. Yapılan literatür taraması sonucunda 6 çalışma ele alınmıştır. Ele alınan bu 6 çalışma sonucunda Oyun Terapinin iyileşmeye tedavide etkili olduğu, iyileşme sürecinde yardımcı olduğu görülmüştür. Dehb sahip bireylerde Oyun Terapi uygulandıktan sonra semptomların azaldığı ve iyileştiği sonucuna ulaşılmıştır. Bu sebeple de Dehb tedavisinde Oyun Terapi etkili bir yöntemdir. Oyun Terapinin Dehb iyileştirmesinde etkili bir model olduğu sonucuna ulaşılmıştır, bu çıkarım sonucunda Dehb tedavisinde kullanılabilir bir modeldir.
The Gaia inertial reference frame and the tilting of the Milky Way disk
Creators: name: Perryman, Michael
name: Spergel, David N.
name: Lindegren, Lennart
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: While the precise relationship between the Milky Way disk and the symmetry planes of the dark matter halo remains somewhat uncertain, a time-varying disk orientation with respect to an inertial reference frame seems probable. Hierarchical structure formation models predict that the dark matter halo is triaxial and tumbles with a characteristic rate of ~2 rad/Hubble time (~30 muas/yr). These models also predict a time-dependent accretion of gas, such that the angular momentum vector of the disk should be misaligned with that of the halo. These effects, as well as tidal effects of the LMC, will result in the rotation of the angular momentum vector of the disk population with respect to the quasar reference frame. We assess the accuracy with which the positions and proper motions from Gaia can be referred to a kinematically non-rotating system, and show that the spin vector of the transformation from any rigid self-consistent catalog frame to the quasi-inertial system defined by quasars should be defined to better than 1 muas/yr. Determination of this inertial frame by Gaia will reveal any signature of the disk orientation varying with time, improve models of the potential and dynamics of the Milky Way, test theories of gravity, and provide new insights into the orbital evolution of the Sagittarius dwarf galaxy and the Magellanic Clouds.
description: 16 pages; accepted for publication in ApJ
Coffee Lecture Slides:  Datenaufbereitung und Qualitätsverbesserung mit OpenRefine
Creators: name: Assmann, Cora
Publisher: name: Zenodo
Year: 2023
Subjects: RDM
FDM
datamanagement
OpenRefine
Tabellendaten

description: English: Coffee Lecture Slides:  "Datenaufbereitung und Qualitätsverbesserung mit OpenRefine"
Do you work with data organized in tables? Do you usually spend more time on data cleansing and data quality improvement than on data analysis? If you can answer YES to these questions, it's worth taking a look at the free open-source tool OpeRefine. In this Coffee Lecture we will give you a short overview of the possibilities OpenRefine offers to improve the quality of your data.
Video: Link 
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Deutsch: Präsentation zur Coffee Lecture "Datenaufbereitung und Qualitätsverbesserung mit OpenRefine" am 18.10.2023
Arbeiten Sie mit Daten, die in Tabellen organisiert sind? Verbringen Sie normalerweise mehr Zeit mit der Datenaufbereitung als mit der Datenanalyse? Wenn Sie diese Fragen mit JA beantworten können, lohnt sich einen Blick auf das kostenloses Open-Source-Tool OpeRefine zu werfen. In der TKFDM Coffee Lecture werden wir Ihne einen kurzen Einblick geben, welche Möglichkeiten Ihnen OpenRefine bietet, die Qualität Ihrer Daten zu verbessern.
Video: Link
Improved Characterization of Focal Liver Lesions With Liver-Specific Gadoxetic Acid Disodium-Enhanced Magnetic Resonance Imaging: A Multicenter Phase 3 Clinical Trial
Creators: name: Mitchell, Donald
name: Sheafor, Douglas H.
name: Bluemke, David A.
name: Brody, Jeffrey
name: Feldman, David R.
name: McTavish, Jeffrey D.
name: Francis, Isaac R.
name: Leary, Christopher
name: Semelka, Richard C.
name: Shamsi, Kohkan
name: Amendola, Marco
name: Fidler, Jeff
name: Sahani, Dushyant
name: Outwater, Eric
name: Gschwend, Simone
name: Breuer, Josy
name: Raman, Steven S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: To evaluate the safety of gadoxetic acid disodium (Gd-EOB-DTPA) magnetic resonance imaging (MRI) and its efficacy in characterizing liver lesions.
A simulation framework to investigate in vitro viral infection dynamics
Creators: name: Sloot, Peter M.A.
name: Mancini, Emiliano
name: Bankhead, Armand
name: Baric, Ralph S.
name: McWeeney, Shannon
name: Sims, Amy C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Virus infection is a complex biological phenomenon for which in vitro experiments provide a uniquely concise view where data is often obtained from a single population of cells, under controlled environmental conditions. Nonetheless, data interpretation and real understanding of viral dynamics is still hampered by the sheer complexity of the various intertwined spatio-temporal processes. In this paper we present a tool to address these issues: a cellular automata model describing critical aspects of in vitro viral infections taking into account spatial characteristics of virus spreading within a culture well. The aim of the model is to understand the key mechanisms of SARS-CoV infection dynamics during the first 24 hours post infection. Using a simulated annealing algorithm we tune free parameters with data from SARS-CoV infection of cultured lung epithelial cells. We also interrogate the model using a Latin Hypercube sensitivity analysis to identify which mechanisms are critical to the observed infection of host cells and the release of measured virus particles.
MPEC 2023-R20 : OBSERVATIONS AND ORBITS OF COMETS AND A/ OBJECTS
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: OBSERVATIONS AND ORBITS OF COMETS AND A/ OBJECTS

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
EDUCATION FOR SUSTAINABLE DEVELOPMENT - AN ANALYSIS OF TEACHING TECHNIQUES OF ESD PEDAGOGIES FOR PROMOTING ENVIRONMENTAL SUSTAINABILITY AMONG HIGHER SECONDARY STUDENTS
Creators: name: DR ARCHANA S.S
Publisher: name: Zenodo
Year: 2022
Subjects: Education for Sustainable Development, Environmental Sustainability, ESD Pedagogies, Teaching techniques, Issue Analysis Technique, Simulations, Class Discussions

description: Abstract Sustainable development is considered as one of the greatest challenges of 21stcentury. Every phase of education is now being urged to declare its support for Education for Sustainable Development (ESD). The present study analyzed the teaching techniques of ESD pedagogies preferred by the teachers for promoting environmental sustainability among Higher Secondary students. The sample selected for the study involves 50 Higher Secondary School Teachers. The method adopted was survey cum descriptive. The findings revealed that Issue Analysis Technique is the most preferred and appropriate teaching technique for promoting environmental sustainability among students.
Solving the inverse problem of noise-driven dynamic networks
Creators: name: Zhang, Zhaoyang
name: Zheng, Zhigang
name: Niu, Haijing
name: Mi, Yuanyuan
name: Wu, Si
name: Hu, Gang
Publisher: name: arXiv
Year: 2014
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Nowadays massive amount of data are available for analysis in natural and social systems. Inferring system structures from the data, i.e., the inverse problem, has become one of the central issues in many disciplines and interdisciplinary studies. In this Letter, we study the inverse problem of stochastic dynamic complex networks. We derive analytically a simple and universal inference formula called double correlation matrix (DCM) method. Numerical simulations confirm that the DCM method can accurately depict both network structures and noise correlations by using available kinetic data only. This inference performance was never regarded possible by theoretical derivation, numerical computation and experimental design.
description: 4 pages, 2 figures
title: Alexander III: a pogrom-maker? : capability and culpability in Russian society, 1881-1894.
Creators: name: Lea. Mian, Natasha
Publisher: name: University of Liverpool Repository
Year: 2023

description: This thesis intends to show that pogroms in the reign of Alexander III were neither encouraged nor instigated by the government. While other historians have demonstrated why the government could not have been involved in a pogrom policy, a thesis to which the author adds new primary source materials, it is possible to go one step further with new information emerging on alternative origins and reasons for the pogroms. It is argued that there was independent anti-Jewish action among the peasantry that clearly shows their capability for self-motivation and organisation. Chapters 1 and 2 review the literature on the Russian peasantry, the nature of the autocracy, the tensions within Russian society and the role of the Jewish population within the Russian Empire until the 1880s. These are the areas on which the crux of the thesis rests. Chapter 3 re-examines the period 1881-1894 in more detail in an effort to understand more clearly Jewish and Russian social perceptions of the pogroms, and how this has led to misconceptions among historians. Chapter 4 looks more closely at the government policy on the Jewish Question, using new data that allows research to take into account the real feelings and concerns that were expressed at the highest levels of government. Chapter 5 considers the same unofficial and frank source of documentation but at lower levels, i. e. police and local officials. From these police reports, comes the factual evidence of the existence of peasant leadership, organisation and movements against authority, and more specifically against Jews. Chapter 6 concludes that by 1881, the autocracy did not control or understand Russian or Jewish society, and it was during the next thirteen years that this became evident. The re-evaluation of available data only serves to show that the pogroms were a clear illustration of this fact.
On the thermodynamic properties of fictitious identical particles and the application to fermion sign problem
Creators: name: Xiong, Yunuo
name: Xiong, Hongwei
Publisher: name: arXiv
Year: 2022
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Computational Physics (physics.comp-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: By generalizing the recently developed path integral molecular dynamics for identical bosons and fermions, we consider the finite-temperature thermodynamic properties of fictitious identical particles with a real parameter $ξ$ interpolating continuously between bosons ($ξ=1$) and fermions ($ξ=-1$). Through general analysis and numerical experiments we find that the average energy may have good analytical property as a function of this real parameter $ξ$, which provides the chance to calculate the thermodynamical properties of identical fermions by an extrapolation with a simple polynomial function after accurately calculating the thermodynamic properties of the fictitious particles for $ξ\geq 0$. Using several examples, it is shown that our method can efficiently give accurate energy values for finite-temperature fermionic systems. Our work provides a chance to circumvent the fermion sign problem for some quantum systems.
description: 24 pages, 7 figures, Accepted by The Journal of Chemical Physics
Disasters management and Public participation!
Creators: name: Dr. Prakash Laxmanrao Dompale
Publisher: name: Zenodo
Year: 2022

description: Abstract: The most beautiful gifts given by nature include air, water, trees. But if the same air assumes a violent form, if the same water shows evil qualities, if the same tree leaves its support, a great calamity may occur. A disaster is a crisis that causes large-scale loss of life, economic and social life to a nation or society and has far-reaching effects on that nation or society. Such a crisis is called a disaster. Disasters are events that have a major impact on humans and the environment. Disasters are unpredictable. A natural disaster is a very terrible and dangerous phenomenon that occurs suddenly and usually causes damage to houses, property, goods and many other types and also causes many deaths. Due to human mistakes, it is increasing day by day as human beings misuse the ecological resources. There are many types of natural disasters such as volcanoes, floods, earthquakes, droughts, landslides, cyclones, tsunamis, avalanches, thunderstorms, heat waves and lightning. Due to some disasters, the economic backbone of the countries has been broken. For this, people should be educated about this disaster, information should be exchanged, training should be given to deal with these situations, a sense of security should be instilled in the general public, financial and medical assistance should be provided to the disaster affected people quickly and proper management should be done during the disaster, it should be the aim of the government, and at the same time the people should also participate. Unfortunately, the poor people of the world are the sure victims of this natural disaster. Recent tsunamis, volcanoes, earthquakes are recent examples of this. For this, the governments of the country and the country hold hands with the media and make a declaration and explain its reasoning to the people