cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 10 of Mitotic arrest affects clustering of tumor cells
Creators: name: Bonnet, Julia
name: Rigal, Lise
name: Mondesert, Odile
name: Morin, Renaud
name: Corsaut, Gaëlle
name: Vigneau, Mathieu
name: Ducommun, Bernard
name: Lobjois, Valérie
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 10: Figure S6. Characterization of clusters in control and experimental conditions. a, b Graphs showing the aspect ratio (a) and circularity (b) analysis results for the larger clusters formed in micro-wells in MCF-7 cells incubated or not (untreated, UNT) with nocodazole and MG132 (i.e., metaphase-synchronized/blocked, Met-sync), or with MG132 (MG) or nocodazole (Noco) alone after 3 h of clustering. Each dot corresponds to the values in one micro-well from 5 independent experiments and bars correspond to the mean ± SD. c, d Determination of the average (µ) (c) and standard deviation (σ) (d) aspect ratio in single MCF-7 cells incubated or not (untreated, UNT) with nocodazole and MG132 (i.e., metaphase-synchronized/blocked, Met-sync), or with MG132 (MG) or nocodazole (Noco) alone after 1 h of aggregation. Each dot corresponds to one cell and the bars correspond to the mean ± SD. Data are from 5 independent experiments with 5-6 cells analyzed per experiment. *P
An Archaeological Repository Minion and Ph.D. Student
Creators: name: MacFarland, Katie
Publisher: name: Archaeology Data Service
Year: 2014

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Families of vector fields with many numerical invariants
Creators: name: Goncharuk, Nataliya
name: Kudryashov, Yury
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 34C23, 37G99, 37E35

description: We study bifurcations in finite-parameter families of vector fields on $S^2$. Recent papers by Yu. Ilyashenko, N. Goncharuk, Yu. Kudryashov, I. Schurov, and N. Solodovnikov provide examples of (locally generic) structurally unstable families of 3-parameter vector fields: generic close 3-parameter families experience different bifurcations. In this paper, we use these results to construct new examples of few-parameter generic families of planar vector fields such that their classification has many invariants. In particular, we construct (a) 3-parameter families with infinitely many numerical invariants; (b) 4-parameter families with arbitrarily many "robust" numerical invariants; (c) 5-parameter families with functional invariants.
Angular Momentum Mixing in Single Flavor Color Superconductivity with Transverse Pairing
Creators: name: Feng, Bo
name: Hou, Defu
name: Ren, Hai-cang
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Because of the equal strength of the pairing potential mediated by one-gluon exchange for all partial waves to the leading order QCD running coupling constant and the nonlinearity of the gap equation, the non-spherical pairing in single flavor color superconductivity(CSC) can not be restricted in a single non-s-wave channel and the mixing among different angular momenta will occur. In this paper, we examine the angular momentum mixing in single flavor CSC with transverse pairing, in which the pairing quarks have opposite helicity. We find that the free energy of all non-spherical pairing states are lowered by angular momentum mixing compared with that contain p-wave only. But the amount of the free energy drop is numerically small. Consequently the most stable pairing state that respect the time reversal invariance remains the spherical CSL.
description: 16 pages, 2 figures, 1 table in Revtex
Magnetotransport through graphene spin valves
Creators: name: Ding, Kai-He
name: Zhu, Zhen-Gang
name: Berakdar, Jamal
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present a theoretical study on the spin-dependent transport through a spin valve consisting of graphene sandwiched between two magnetic leads with an arbitrary orientation of the lead magnetization. No gate voltage is applied. Using Keldysh's nonequilibrium Green's function method we show that, in absence of external magnetic fields, the current-voltage curves are nonlinear. Around zero bias the differential conductance versus bias voltage possesses a strong dip. The zero-bias anomaly in the tunnel magnetoresistance (TMR) is affected strongly by the leads spin polarization. Depending on the value of the bias voltage TMR exhibits a behavior ranging from an insulating to a metallic-type. In presence of a static external magnetic field the differential conductance and TMR as a function of the bias voltage and the strength of the magnetic field show periodic oscillations due to Landau-level crossings. We also inspect the effects of the temperature and the polarization degrees on the differential conductance and TMR.
Foreign direct investment and economic ethnocentrism in Japan
Creators: name: Uchiyama, Hiroyuki
Publisher: name: University of British Columbia
Year: 2012

description: This study has a twofold purpose. The first is to investigate the background and development of Japan's policy on the liberalization of international capital movements and the second is to explore the characteristics of Japanese economic nationalism. By the late 1960's Japan had succeeded in expanding her economy to the level of the economies in the European countries. Rapid increases in U.S. imports from Japan, which reflected Japanese economic expansion made U.S. enterprises realize that Japanese industry had become strong enough to decontrol foreign investment in Japan to a further extent than she had until then. But the Japanese thought that their industry was not developed enough to compete with multinational corporations because of the inherent vulnerability of Japanese enterprises and industries arising from the financial incapability of firms and excessive competition in major industries. Thus Japan has maintained a restrictive policy on foreign inward investment, with the principle that every Japanese industry should be controlled by nationals. In the course of her economic development, Japan proceeded with a five-year capital liberalization program from 1967 to 1971. Nevertheless, Japan's economic policy on foreign investment remains more restrictive than those of Western developed countries. Japanese policy is significantly affected by feelings of economic nationalism rather than considerations of economic welfare. In this paper a model of economic ethnocentrism is formulated with the purpose of explaining the characteristics of economic nationalism in Japan. Japan possesses unique social, cultural and political conditions which have lasted for a long time. These unique traditional traits of Japanese society remain influential enough that Japan's industrial organization, formal and informal, is able to be distinguished from that of Western countries. The basic attitudes of the Japanese towards foreign investment are derived from complex economic, socio-cultural and political conditions. This study attempts to synthesize several major factors which affect the Japanese attitudes which influence policies on foreign investment in Japan.
On Hastings' counterexamples to the minimum output entropy additivity conjecture
Creators: name: Brandao, Fernando G. S. L.
name: Horodecki, Michal
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Hastings recently reported a randomized construction of channels violating the minimum output entropy additivity conjecture. Here we revisit his argument, presenting a simplified proof. In particular, we do not resort to the exact probability distribution of the Schmidt coefficients of a random bipartite pure state, as in the original proof, but rather derive the necessary large deviation bounds by a concentration of measure argument. Furthermore, we prove non-additivity for the overwhelming majority of channels consisting of a Haar random isometry followed by partial trace over the environment, for an environment dimension much bigger than the output dimension. This makes Hastings' original reasoning clearer and extends the class of channels for which additivity can be shown to be violated.
description: 17 pages + 1 line
Horizons - Old and New
Creators: name: Reynolds, Ffion
Publisher: name: Archaeology Data Service
Year: 2014

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Multiplexed electrophoretic systems for the detection and identification of small ions
Creators: name: Gaudry, AJ
Publisher: name: University Of Tasmania
Year: 2023

description: Capillary electrophoresis (CE) is regarded as a powerful separation technique that is an alternative or complementary technique to more traditional methods such as gel electrophoresis and liquid chromatography. When applied to the separation of inorganic species, capillary electrophoresis still continues to take second place to other competitive techniques such as ion chromatography (IC) and elemental mass spectrometry. CE is often touted as having several obvious advantages over chromatographic techniques (mostly IC) including high resolving power, speed, instrumental simplicity, flexibility and cost‚ÄövÑv™efficiency. On the other hand, CE is frequently cited as having a number of comparative disadvantages such as poor reproducibility and sensitivity. The work undertaken in this thesis describes technical innovations to harness the inherent advantages of CE whilst minimising the disadvantages as part of the development of a system for the rapid determination of common small environmental anions and cations. It is unique in its capability to analyse directly from a sample flow, making it especially attractive for monitoring purposes. To enable a move from a capillary to a chip‚ÄövÑv™based system, simple, low cost techniques for the manufacture of polymeric microchips and the incorporation of detection electrodes were developed using limited resources to provide further improvements in speed and reduce resource consumption. A multiplexed polymeric microchip system was developed employing a novel hydrodynamic injection mechanism to reduce sample matrix effects and injection bias, and to improve the quantitative performance of the system. Finally, a compact multipurpose microfluidic platform is developed to support future research interests.
Uniform distribution in nilmanifolds along functions from a Hardy field
Creators: name: Richter, Florian K.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: We study equidistribution properties of translations on nilmanifolds along functions of polynomial growth from a Hardy field. More precisely, if $X=G/Γ$ is a nilmanifold, $a_1,\ldots,a_k\in G$ are commuting nilrotations, and $f_1,\ldots,f_k$ are functions of polynomial growth from a Hardy field then we show that
 $\bullet$ the distribution of the sequence $a_1^{f_1(n)}\cdot\ldots\cdot a_k^{f_k(n)}Γ$ is governed by its projection onto the maximal factor torus, which extends Leibman's Equidistribution Criterion form polynomials to a much wider range of functions; and
 $\bullet$ the orbit closure of $a_1^{f_1(n)}\cdot\ldots\cdot a_k^{f_k(n)}Γ$ is always a finite union of sub-nilmanifolds, which extends some of the previous work of Leibman and Frantzikinakis on this topic.
description: 49 pages, 2nd revised version after referee comments
Interns and Training: You Get What You Put Into Them.
Creators: name: Head, Serra
Publisher: name: Archaeology Data Service
Year: 2014

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Cakes, Cottages and Manky Bones
Creators: name: , Gabe
Publisher: name: Archaeology Data Service
Year: 2014

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
A method to quantitatively evaluate Hamaker constant using the jump-into-contact effect in Atomic Force microscopy
Creators: name: Das, Soma
name: Sreeram, P. A.
name: Raychaudhuri, A. K.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We find that the jump-into-contact of the cantilever in the atomic force microscope (AFM) is caused by an inherent instability in the motion of the AFM cantilever. The analysis is based on a simple model of the cantilever moving in a nonlinear force field. We show that the jump-into-contact distance can be used to find the interaction of the cantilever tip with the surface. In the specific context of the attractive van der Waals interaction, this method can be realized as a new method of measuring the Hamaker constant for materials. The Hamaker constant is determined from the deflection of the cantilever at the jump-into-contact using the force constant of the cantilever and the tip radius of curvature, all of which can be obtained by measurements. The results have been verified experimentally on a sample of cleaved mica, a sample of Si wafer with natural oxide and a silver film, using a number of cantilevers with different spring constants. We emphasize that the method described here is applicable only to surfaces that have van der Waals interaction as the tip-sample interaction. We also find that the tip to sample separation at the jump-into-contact is simply related to the cantilever deflection at this point, and this provides a method to exactly locate the surface.
description: 11 pages, 4 figures, 1 table
Additional file 1 of Mitotic arrest affects clustering of tumor cells
Creators: name: Bonnet, Julia
name: Rigal, Lise
name: Mondesert, Odile
name: Morin, Renaud
name: Corsaut, Gaëlle
name: Vigneau, Mathieu
name: Ducommun, Bernard
name: Lobjois, Valérie
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 1: Figure S1. Synchronization procedure. a Flow cytometry analysis of control (untreated) and mitosis-arrested cells (nocodazole/MG132). Mitotic cells were detected with the mitotic-specific monoclonal 3-12-I-22 antibody. b Representative fluorescence microscopy images (DAPI and α-tubulin) of cells blocked in mitosis (nocodazole/MG132) and used for the clustering assays. Scale bar: 10 µm.
Hot carriers in an intrinsic graphene
Creators: name: Balev, O. G.
name: Vasko, F. T.
name: Ryzhii, V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Heating of carriers in an intrinsic graphene under dc electric field is considered taking into account the intraband energy relaxation due to acoustic phonon scattering and the interband generation-recombination transitions due to thermal radiation. The distribution of nonequilibrium carriers is obtained for the cases when the intercarrier scattering is unessential and when the carrier-carrier Coulomb scattering effectively establishes the quasiequilibrium distribution with the temperature and the density of carriers that are determined by the balance equations. Because of an interplay between weak energy relaxation and generation-recombination processes a very low threshold of nonlinear response takes place. The nonlinear current-voltage characteristics are calculated for the case of the momentum relaxation caused by the elastic scattering. Obtained current-voltage characteristics show low threshold of nonlinear behavior and appearance of the second ohmic region, for strong fields.
description: 9 pages, 8 figures
Have compass, will travel: A cemetery mapping project
Creators: name: Barnes, Jodi
Publisher: name: Archaeology Data Service
Year: 2014

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
Production and characterization of a fragmented spinor Bose-Einstein condensate
Creators: name: Evrard, Bertrand
name: Qu, An
name: Dalibard, Jean
name: Gerbier, Fabrice
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Understanding the ground state of many-body fluids is a central question of statistical physics. Usually for weakly interacting Bose gases, most particles occupy the same state, corresponding to a Bose--Einstein condensate. However, another scenario may occur with the emergence of several, macroscopically populated single-particle states. The observation of such fragmented states remained elusive so far, due to their fragility to external perturbations. Here we produce a 3-fragment condensate for a spin 1 gas of $\sim 100$ atoms, with anti-ferromagnetic interactions and vanishing collective spin. Using a spin-resolved detection approaching single-atom resolution, we show that the reconstructed many-body state is quasi-pure, while one-body observables correspond to a mixed state. Our results highlight the interplay between symmetry and interaction to develop entanglement in a quantum system.
description: Supplementary material available as ancillary file
Autonomous learning of nonlocal stochastic neuron dynamics
Creators: name: Maltba, Tyler E.
name: Zhao, Hongli
name: Tartakovsky, Daniel M.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: Numerical Analysis (math.NA)
subject: Quantitative Methods (q-bio.QM)
subject: Machine Learning (stat.ML)
subject: FOS: Biological sciences
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: Neuronal dynamics is driven by externally imposed or internally generated random excitations/noise, and is often described by systems of random or stochastic ordinary differential equations. Such systems admit a distribution of solutions, which is (partially) characterized by the single-time joint probability density function (PDF) of system states. It can be used to calculate such information-theoretic quantities as the mutual information between the stochastic stimulus and various internal states of the neuron (e.g., membrane potential), as well as various spiking statistics. When random excitations are modeled as Gaussian white noise, the joint PDF of neuron states satisfies exactly a Fokker-Planck equation. However, most biologically plausible noise sources are correlated (colored). In this case, the resulting PDF equations require a closure approximation. We propose two methods for closing such equations: a modified nonlocal large-eddy-diffusivity closure and a data-driven closure relying on sparse regression to learn relevant features. The closures are tested for the stochastic non-spiking leaky integrate-and-fire and FitzHugh-Nagumo (FHN) neurons driven by sine-Wiener noise. Mutual information and total correlation between the random stimulus and the internal states of the neuron are calculated for the FHN neuron.
description: 28 pages, 12 figures, First author: Tyler E. Maltba, Corresponding author: Daniel M. Tartakovsky
Additional file 2 of Mitotic arrest affects clustering of tumor cells
Creators: name: Bonnet, Julia
name: Rigal, Lise
name: Mondesert, Odile
name: Morin, Renaud
name: Corsaut, Gaëlle
name: Vigneau, Mathieu
name: Ducommun, Bernard
name: Lobjois, Valérie
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 2: Figure S2. Impact of incubation with MG132 alone on MCF-7 cells clustering. a Control (untreated) and MG132-treated MCF-7 cells were seeded in 96-well low-attachment plates and monitored by video-microscopy for 5 h. Representative transmitted light microscopy images of cell aggregation at the indicated time points. Segmentation (red line) was performed using a dedicated MATLAB software. Green lines correspond to the excluded holes, and blue to isolated cells. b Using the automated image processing data, the aggregate area was measured over time. The graph corresponds to the percentage of compaction calculated from the normalized area variation relative to the time 0. Data correspond to the mean ± SD of 48 aggregates for each condition from 3 independent experiments. a and b The data of the Fig. 2 obtained with metaphase-synchronized cells are shown for comparison.
Measuring atomic NOON-states and using them to make precision measurements
Creators: name: Hallwood, David W.
name: Stokes, Adam
name: Cooper, Jessica J.
name: Dunningham, Jacob
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A scheme for creating NOON-states of the quasi-momentum of ultra-cold atoms has recently been proposed [New J. Phys. 8, 180 (2006)]. This was achieved by trapping the atoms in an optical lattice in a ring configuration and rotating the potential at a rate equal to half a quantum of angular momentum . In this paper we present a scheme for confirming that a NOON-state has indeed been created. This is achieved by spectroscopically mapping out the anti-crossing between the ground and first excited levels by modulating the rate at which the potential is rotated. Finally we show how the NOON-state can be used to make precision measurements of rotation.
description: 14 preprint pages, 7 figures
Alexandria Archaeology: We Dig Virginia s History
Creators: name: Stohr, Whitney
Publisher: name: Archaeology Data Service
Year: 2014

description: This resource is a single blog post created as part of the Day of Archaeology initiative. The Day of Archaeology project aimed to provide a window into the daily lives of archaeologists from all over the world. The project asked people working, studying or volunteering in the archaeological world to participate in a 'Day of Archaeology' each year by recording their day and sharing it through text, images or video on the Day of Archaeology blog.
The project asked anyone with a personal, professional or voluntary interest in archaeology to get involved, and help highlight the reasons why archaeology is vital to protect the past and inform our futures. The resulting Day of Archaeology project archive demonstrates the wide variety of work the archaeological profession undertakes day-to-day across the globe, and helps to raise public awareness of the relevance and importance of archaeology to the modern world.
The first ever Day of Archaeology was held in 2011 and, since then, the project had thousands of archaeologists take part in the event, from those working in the field through to specialists working in laboratories and behind computers. The last Day of Archaeology was on Friday 28th July 2017.
title: Mechanisms of pathological adipogenesis
Creators: name: Bastien, M
Publisher: name: Liverpool John Moores University
Year: 2019

description: Although adipose tissue plays important physiological roles, the increase in adiposity with aging is a common feature in several pathologies, including some forms of osteoporosis. Ion channels and ghrelin signalling have been shown to be involved in regulating many cell processes such as proliferation, differentiation and apoptosis, particularly in bone. This thesis investigated the roles of ghrelin and ion channels in the adipogenic differentiation of 7F2 preosteoblastic cells. The amount of Oil Red O stain increased by 135%, and the mRNA expression of two adipocytic markers, PPARγ (5.46 ± 0.22; p = 0.024) and C/EBPα (25.3 ± 0.21; p = 0.0048), was higher in 7F2 cells cultured with adipogenic medium compared with basal medium, indicating that 7F2 cells differentiated into adipocytes. 7F2 cells also expressed previously unreported variant isoforms of ghrelin at the mRNA level; these variants isoforms were much more abundant than native ghrelin. 7F2 cells also express the other key genes from ghrelin signalling, i.e. Ghsr and Mboat4, suggesting that ghrelin or its variant isoforms may have autocrine/paracrine effects in these cells. Ghrelin mRNA expression was higher in 7F2 cells treated with basal medium + 200 nM ghrelin (144.84 ± 0.58) and adipogenic medium + 200 nM ghrelin (123.07 ± 0.33) compared with cells cultured with basal medium alone (p = 0.01), and adipogenic medium alone (0.79 ± 0.40; p = 0.0089), respectively. Treatment with 20 nM and 200 nM ghrelin had no significant effect on lipid content and on osteoblastic and adipocytic markers mRNA levels (p > 0.05). On the contrary, cell numbers were lower in 7F2 cells cultured with the voltage-gated K+ channel blocker tetraethylammonium, and lipid droplets inside 7F2 cell-derived adipocytes were smaller compared with cells cultured with adipogenic medium alone, suggesting that voltage-gated K+ channels are involved in regulating cell proliferation and adipogenic differentiation. 7F2 cells and 7F2 cell-derived adipocytes expressed the KATP channel subunits Kcnj8 and Sur2B, and the BK channel subunits Kcnma1 and Kcnmb2. 12 types of functional ion channels were detected in electrophysiology experiments but could not be identified. In conclusion, ghrelin treatment did not inhibit adipogenic differentiation in 7F2 cells, but 7F2 cells expressed previously unreported variant isoforms of ghrelin and ion channels which may play important roles in regulating osteoblast functions and adipogenic differentiation. Future work is required to confirm the presence of ghrelin variants at the protein level, and to study the roles of these variants and ionic mechanisms in bone metabolism. A better understanding of the mechanisms underlying pathological adipogenesis in bone may provide interesting therapeutic targets for disorders such as osteoporosis.
Stark effect on emission spectra of carbon monoxide
Creators: name: Fisher, Nina Jo-Anne
Publisher: name: University of British Columbia
Year: 2012

description: The electronic emission spectra of the CO molecule in an applied electric field of 53.8 kilovolts/cm has been observed. The electric field was determined from the Stark Effect on the H line at 4340Å. The spectra were produced in the high field region of a low pressure glow discharge using carbon monoxide gas and water vapour. The electric dipole moment of the CO molecule has been determined for the BlΣ+ state using the P(l) transition of the Ångstrom ( 0 , 0 ) band. The effect observed is a second order effect in the B1Σ+ state and it has been deduced that the dipole moment of the A1π state is very small or zero. The dipole moment of the B1Σ+ state is 1.61 debye ± 14%.
The Practice of Self-Understanding
Creators: name: Mortari, Luigina
Publisher: name: Thaumàzein | Rivista di Filosofia
Year: 2016
Subjects: Emotional Life; Education; Self-Reflectivity

description: To shed new light on the importance of self-care, it is fundamental to pinpoint the role of the emotional life for this process of self-inquiry. The action of knowing raises ethical issues, even more when dealing with the intimate essence of the person; respecting a delicate ethics is the ground for dealing with such investigation. After an analysis of philosophical and spiritual examples which focus on feelings and affective education, I provide a phenomenological account that introduces some methods for self-understanding and a possible self-transformation.
description: Thaumàzein | Rivista di Filosofia, Vol 3 (2015): Max Scheler and the Emotional Turn
Hubble, Hubble's law and the expanding universe
Creators: name: Bagla, J. S.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences

description: Hubble's name is associated closely with the idea of an expanding universe as he discovered the relation between the recession velocity and distances of galaxies. Hubble also did a lot of pioneering work on the distribution of galaxies in the universe. In this article we take a look at Hubble's law and discuss how it relates with models of the universe. We also give a historical perspective of the discoveries that led to the Hubble's law.
description: 10 pages, 1 figure
Additional file 3 of Mitotic arrest affects clustering of tumor cells
Creators: name: Bonnet, Julia
name: Rigal, Lise
name: Mondesert, Odile
name: Morin, Renaud
name: Corsaut, Gaëlle
name: Vigneau, Mathieu
name: Ducommun, Bernard
name: Lobjois, Valérie
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 3: Figure S3. MCF-7 cell clustering occurs independently of microtubules cytoskeleton disruption. a Immunostaining of -tubulin on control untreated MCF-7 cells (Control) and cells incubated with 10 µM nocodazole for 2 h. For both conditions, each row corresponds to two different fields of view. Inserts show the higher magnification of the region outlined with dotted lines in the corresponding image. *mitotic cells in control and nocodazole conditions. Scale bar: 10 µm. b Schematic representation of the experiment. To test the impact of microtubule depolymerization on aggregation dynamics, MCF-7 cells were pre-treated with 10 µM nocodazole for 1 h, then they were seeded in 96-well low-attachment plates in presence of 10 µM nocodazole, and monitored by video-microscopy for 5 h (clustering assay). c Percentage of compaction calculated from the normalized area at each time points (see “Methods” section) for control (untreated) cells and cells incubated with nocodazole, as described in b. For each time point, data correspond to the mean ± SD of 32 aggregates/condition from 3 independent experiments.
Converting between quadrilateral and standard solution sets in normal surface theory
Creators: name: Burton, Benjamin A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Geometric Topology (math.GT)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 52B55 (Primary) 57N10, 57N35 (Secondary)

description: The enumeration of normal surfaces is a crucial but very slow operation in algorithmic 3-manifold topology. At the heart of this operation is a polytope vertex enumeration in a high-dimensional space (standard coordinates). Tollefson's Q-theory speeds up this operation by using a much smaller space (quadrilateral coordinates), at the cost of a reduced solution set that might not always be sufficient for our needs. In this paper we present algorithms for converting between solution sets in quadrilateral and standard coordinates. As a consequence we obtain a new algorithm for enumerating all standard vertex normal surfaces, yielding both the speed of quadrilateral coordinates and the wider applicability of standard coordinates. Experimentation with the software package Regina shows this new algorithm to be extremely fast in practice, improving speed for large cases by factors from thousands up to millions.
description: 55 pages, 10 figures; v2: minor fixes only, plus a reformat for the journal style
Additional file 2 of Clinical and genetic spectrum of 14 cases of NLRP3-associated autoinflammatory disease (NLRP3-AID) in China and a review of the literature
Creators: name: Zhou, Yu
name: Wang, Wei
name: Zhong, Linqing
name: Wang, Lin
name: Ma, Mingsheng
name: Tang, Xiaoyan
name: Li, Zhuo
name: Wang, Changyan
name: Gou, Lijuan
name: Zhang, Tiannan
name: Song, Hongmei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health

description: Additional file 2: Table S1. Detailed clinical manifestations of CAPS patients in China according to literature.
title: Conditional FAVAR and scenario analysis for a large data: case of Tunisia
Creators: name: Ben Romdhane, Hager
name: Ben Tanfous, Nahed
Publisher: name: Graduate Institute of International and Development Studies
publisherIdentifier: https://ror.org/007ygn379
publisherIdentifierScheme: ROR
Year: 2017

description: Graduate Institute of International and Development Studies Working Paper ; no. 15/2017
Additional file 4 of Mitotic arrest affects clustering of tumor cells
Creators: name: Bonnet, Julia
name: Rigal, Lise
name: Mondesert, Odile
name: Morin, Renaud
name: Corsaut, Gaëlle
name: Vigneau, Mathieu
name: Ducommun, Bernard
name: Lobjois, Valérie
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Additional file 4: Figure S4. Aggregation ability of cells accumulated in mitosis independently of microtubule cytoskeleton disruption is also altered. a Flow cytometry analysis of control (untreated) cells, cells incubated with 6 µM RO3306 (RO3306) for 20 h, or cells at the indicated time points after RO3306 removal from the culture medium. The upper panels show the histograms of the propidium iodide fluorescence intensity (DNA content) and the lower panels show the dot plots of DNA content versus intensity for the detection of the mitotic marker 3.12.I.22 (see “Methods” section). The percentage of mitotic cells (shown in green) is indicated for each condition. b Schematic representation of the experimental design for the aggregation assay. c The percentage of compaction was calculated at each time point of the clustering assay in control cells and in cells collected by shake-off at 2 h after RO3306 removal. Data correspond to the mean ± SD of 32 aggregates in control and 35 aggregates in treated cells from 3 independent experiments.
Multicolor continuous-variable quantum entanglement in the Kerr frequency comb
Creators: name: Li, Ming
name: Zhang, Yan-Lei
name: Xu, Xin-Biao
name: Dong, Chun-Hua
name: Guo, Guang-Can
name: Zou, Chang-Ling
Publisher: name: arXiv
Year: 2021
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In a traveling wave microresonator, the cascaded four-wave mixing (FWM) between optical modes allows the generation of frequency combs, including intriguing dissipative Kerr solitons (DKS). In this study, we explore the quantum fluctuations of frequency combs and unveil the quantum features of solitons. The entanglement of DKS exhibits two distinct characteristics. For modes located at the spectral edge with a small number of excitations, different comb modes with multiple colors become entangled due to photon-pair generation and coherent photon conversion stimulated by the FWM. Notably, we observe a sudden disappearance of quantum entanglement in the center of the DKS spectrum, which is attributed to the self-locking phenomena in the FWM network. Our findings demonstrate the prominent quantum nature of DKS, which is of fundamental significance in quantum optics and has the potential to be utilized in quantum networking and distributed quantum sensing applications.
description: 7 pages,3 figures
Odd parity charge density-wave scattering in cuprates
Creators: name: Seibold, G.
name: Grilli, M.
name: Lorenzana, J.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate a model where superconducting electrons are coupled to a frequency dependent charge-density wave (CDW) order parameter Delta(w). Our approach can reconcile the simultaneous existence of low energy Bogoljubov quasiparticles and high energy electronic order as observed in scanning tunneling microscopy (STM) experiments. The theory accounts for the contrast reversal in the STM spectra between positive and negative bias observed above the pairing gap. An intrinsic relation between scattering rate and inhomogeneities follows naturally.
description: 5 pages, 3 figures
IMPACT OF VITAMIN D DEFICIENCY, DYSLIPIDEMIA AND OBESITY ON SERUM LIPIDOMIC PROFILE. SEARCH FOR NEW BIOMARKERS AS EARLY PREDICTORS OF OBESITY-ASSOCIATED COMORBIDITIES.
Creators: name: BARBACINI, PIETRO
Publisher: name: Universit� degli Studi di Milano
Year: 2020

description: Research studies indicate that up to 58% of the world adult population will be overweight or obese by 2030 [1]. Obesity is not only related to food intake, but factors such as lifestyle and genetic background contribute to its onset [3?5]. This disease [2] is commonly associated with vitamin D (Vit. D) deficiency [6,7], and genetic associations have been identified to explain this link [8]; however, differences in dietary intake, sun exposure, or Vit. D metabolism are also involved [9]. Moreover, along with Vit. D deficiency, lipids, and particularly sphingolipids (SLs) as ceramides (Cers) and sphingomyelins (SMs) have been described as involved, not only in increasing inflammation [10,11], but also in the development of cardiovascular disease and type two diabetes [12?14], two common conditions observed in obese subjects. Given the pivotal role of SLs in obesity associated co-morbidities and the association of Vit. D, dyslipidemia and obesity, our study was aimed at profiling circulating SLs in human subjects under these conditions, in order to provide hints for the identification of new biomarkers to be introduced in clinical settings. To define human SLs profile in obesity, dyslipidemia, and Vit. D associated deficiency, sera from 23 normal-weight normolipidemic (NWNL), 46 normal-weight, dyslipidemic, Vit. D deficient (NWDL) and 60 obese dyslipidemic, Vit. D deficient (ODL) Saudi Arabian subjects were analyzed with a dual approach, characterized by the use of two complementary techniques: the HPTLC-Primuline profiling and the LC-MS analysis. Furthermore, to define SLs profiles in the context of human adaptation to high altitude hypoxia, sera from 59 Vit. D deficient dyslipidemic children living at high altitude were analyzed by LC-MS. Children were grouped based on their BMI percentiles in 7 underweight (UW), 30 normal-weight (NW), 13 overweight (OW) and 9 obese (O). SLs profile analysis of NWNL and ODL Saudi Arabian subjects displayed differences in total Cer and total SM caused by dyslipidemia and vitamin D deficiency, whereas specific Cers, and SMs acyl chains characterize obese subjects, only. Gender differences were found in SLs profiles independently from dyslipidemia and Vit. D status. Obesity-associated Cers, SMs, and dihydrosphingomyelins (dhSMs) specific acyl chains were identified in the NWDL vs. ODL comparison independently from dyslipidemia and Vit D status, and are thought to be drivers of increased risk of developing obesity-associated morbidities. The analysis of SLs profiles from dyslipidemic children with Vit. D deficiency allowed to confirm the results of Saudi Arabian subjects regarding SLs association with dyslipidemia and associated Vit. D deficiency. Furthermore, SLs profile analysis led to the identification of a characteristic SLs portraits associated with BMI and related to hypoxia metabolic adaptation.
Quasi-relativistic approach to analytical gradients of parity violating potentials
Creators: name: Brück, Sascha A
name: Sahu, Nityananda
name: Gaul, Konstantin
name: Berger, Robert
Publisher: name: arXiv
Year: 2021
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: An analytic gradient approach for the computation of derivatives of parity-violating (PV) potentials with respect to displacements of the nuclei in chiral molecules is described and implemented within a quasirelativistic mean-field framework. Calculated PV potential gradients are utilised for estimating PV frequency splittings between enantiomers in rotational and vibrational spectra of four chiral polyhalomethanes, i.e. CHBrClF, CHClFI, CHBrFI and CHAtFI. Values calculated within the single-mode approximation for the frequency shifts agree well with previously reported theoretical values. The influence of non-separable anharmonic effects (multi-mode effects) on the vibrational frequency shifts, which are readily accessible with the present analytic derivative approach, are estimated for the C--F stretching fundamental of all four molecules and computed for each of the fundamentals in CHBrClF and CHAtFI. Multi-mode effects are found to be significant, in particular for the C--F stretching modes, being for some modes and cases of similar size as the single-mode contribution.
description: 20 p/8 fig/4 tab/suppl: 26 tab; minor text changes/corr, eqs 2/27 corr; Numer. vals changed slightly per: more consist. use of fin. nucl; same numer. grid for zora/pv oper. matrix elem. and derivs; improved acc. in assem. of DFT grad; tighter conv. crit. in HF at CHClFI(eq); fewer digits; Tab I/II vals from fin. suppl. of ref 40, as prev. earlier version was linked on publ.'s webpage