cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The low-mass population in the young cluster Stock 8: Stellar properties and Initial Mass Function
Creators: name: Jose, Jessy
name: Herczeg, Gregory J.
name: Samal, Manash R.
name: Fang, Qiliang
name: Panwar, Neelam
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The evolution of HII regions/supershells can trigger a new generation of stars/clusters at their peripheries, with environmental conditions that may affect the initial mass function, disk evolution and star formation efficiency. In this paper we study the stellar content and star formation processes in the young cluster Stock 8, which itself is thought to be formed during the expansion of a supershell. We present deep optical photometry along with JHK and 3.6, 4.5 μm photometry from UKIDSS and Spitzer-IRAC. We use multi-color criteria to identify the candidate young stellar objects in the region. Using evolutionary models, we obtain a median log(age) of ~6.5 (~3.0 Myr) with an observed age spread of ~0.25 dex for the cluster. Monte Carlo simulations of the population of Stock 8, based on estimates for the photometric uncertainty, differential reddening, binarity, and variability, indicate that these uncertainties introduce an age spread of ~0.15 dex. The intrinsic age spread in the cluster is ~0.2 dex. The fraction of young stellar objects surrounded by disk is ~35%. The K-band luminosity function of Stock 8 is similar to that of the Trapezium cluster. The IMF of Stock 8 has a Salpeter- like slope at >0.5 Msun and the IMF flattens and peaks at ~0.4 Msun, below which declines into the substellar regime. Although Stock 8 is surrounded by several massive stars, there seems to be no severe environmental effect in the form of IMF due to the proximity of massive stars around the cluster.
description: Accepted for publication in ApJ
title: Die Bedeutung der "Horizontalstratigraphie" für die relative Chronologie westgotenzeitlicher Nekropolen
title: Die Bedeutung der "Horizontalstratigraphie" für die relative Chronologie westgotenzeitlicher Nekropolen
titleType: Subtitle
Creators: name: Sasse-Kunst, Barbara
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Toledo (Ciudad)
subject: Toledo (Ciudad)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Additional file 15: Table S5. of Genomic repeats, misassembly and reannotation: a case study with long-read resequencing of Porphyromonas gingivalis reference strains
Creators: name: Acuña-Amador, Luis
name: Primot, Aline
name: Cadieu, Edouard
name: Roulet, Alain
name: Barloy-Hubler, Frédérique
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Core genes with pseudogenisation. Gene names and products are listed for all 36 genes that are present in this subset of core genes. An asterisk indicates the strains in which they are pseudogenised, and genes with pseudogenes in more than one strain are bold. (PDF 35 kb)
Elicitação gramatical sobre Juma com anotações / Grammatical elicitation on Juma with notes
Creators: name: Juma, Mandei
name: Dos Santos, Wesley
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2025
Subjects: subject: jua

description: Este conjunto de arquivos contém gravações de vídeo da variedade Juma (ISO jua) da língua Kawahiva e provêm de sessões de elicitação gramatical com a consultora Mandei Juma (identificada pelas iniciais mju) com o linguista Wesley Nascimento dos Santos (identificado pelas iniciais wns) em setembro de 2020, por Zoom.

Essas gravações somam o total de 7 arquivos .mp4. A estrutura do rótulo do arquivo está assim definida:

jua_data_abreviação.do.nome.da.consultora_abreviação.do.nome.do.linguista._número.da.sessão_elicit.mp4

As anotações realizadas durante essas seções de elicitação estão no documento PDF.

= = = = = = = = = = = = = = = = = = = =

This file bundle contains video recordings of the Juma variety (ISO jua) of the Kawahíva language and comes from grammatical elicitation sessions with the consultant Mandei Juma (identified with the initials mju) with the linguist Wesley Nascimento dos Santos (identified with the initials wns) in September 2020 on Zoom.

These recordings total 7 files in mp4 format. The structure of the file name is as follows:

language.ISO.code_date_consultant.abbreviation_collector.abbreviation_number_elicit.mp4

The field notes taken during the sessions are in the pdf document.
Additional file 5 of Development and psychometric properties of surveys to assess patient and family caregiver experience with care transitions
Creators: name: Sorra, Joann
name: Zebrak, Katarzyna
name: Carpenter, Deborah
name: Famolaro, Theresa
name: Rauch, John
name: Li, Jing
name: Davis, Terry
name: Nguyen, Huong Q.
name: McIntosh, Megan
name: Mitchell, Suzanne
name: Hirschman, Karen B.
name: Levine, Carol
name: Clouser, Jessica Miller
name: Brock, Jane
name: Williams, Mark V.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 5.
title: Anmerkungen zu Reccopolis
title: Anmerkungen zu Reccopolis
titleType: Subtitle
Creators: name: Raddatz, Klaus
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Recópolis (Zorita de los Canes, Guadalajara)
subject: Recópolis (Zorita de los Canes, Guadalajara)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
title: Eine selten wiedergegebene Jagdtechnik: Der Einsatz von Leinen mit Blendzeug nach Darstellungen in Conimbriga, Centcelles und Qusayr'Amra
title: Eine selten wiedergegebene Jagdtechnik: Der Einsatz von Leinen mit Blendzeug nach Darstellungen in Conimbriga, Centcelles und Qusayr'Amra
titleType: Subtitle
Creators: name: Arbeiter, Achim
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Centcelles (Constantí, Tarragona)
subject: Conimbriga (Codeixa-a-Velha, Port.)
subject: Centcelles (Constantí, Tarragona)
subject: Conimbriga (Codeixa-a-Velha, Port.)
subject: Centcelles (Constantí, Tarragona)
subject: Conimbriga (Codeixa-a-Velha, Port.)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Additional file 6: of Functional health state description and valuation by people aged 65 and over: a pilot study
Creators: name: Riaan Botes
name: Vermeulen, Karin
name: Adelita Ranchor
name: Buskens, Erik
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 60506 Virology

description: VAS example. Description of data: Example of the Visual Analogue Scale utilized in the study. (DOCX 13Â kb)
Crossing and anti-crossing effects of polaritons in a magnetic-semiconductor superlattice influenced by an external magnetic field
Creators: name: Tuz, Vladimir R.
name: Fesenko, Volodymyr I.
name: Fedorin, Illia V.
name: Sun, Hong-Bo
name: Shulga, Valeriy M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Crossing and anti-crossing effects in dispersion characteristics of both bulk and surface polaritons in a magnetic-semiconductor superlattice influenced by an external static magnetic field being in the Faraday geometry are discussed. The bulk polaritons are classified as eigenwaves with right-handed and left-handed elliptically polarized states, whereas the surface polaritons are considered as hybrid modes having a predominant effect of either magnetic or semiconductor subsystem, and distinctions in dispersion characteristics of such polaritons are revealed involving the concept of critical points.
description: 20 pages, 4 figures
title: Wirkungen der Gruppe von San Ildefonso
title: Wirkungen der Gruppe von San Ildefonso
titleType: Subtitle
Creators: name: Sichtermann, Helmut
Publisher: name: Deutsches Archäologisches Institut
Year: 2020

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
A Close-up View of the Young Circumbinary Disk HD 142527
Creators: name: Boehler, Y.
name: Weaver, E.
name: Isella, A.
name: Ricci, L.
name: Grady, C.
name: Carpenter, J.
name: Perez, L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present ALMA observations of the 0.88 millimeter dust continuum, 13CO, and C18O J=3-2 line emission of the circumbinary disk HD142527 at a spatial resolution of about 0.25". This system is characterized by a large central cavity of roughly 120 AU in radius, and asymmetric dust and gas emission. By comparing the observations with theoretical models, we find that the azimuthal variations in gas and dust density reach a contrast of 54 for dust grains and 3.75 for CO molecules, with an extreme gas-to-dust ratio of 1.7 on the dust crescent. We point out that caution is required in interpreting continuum subtracted maps of the line emission as this process might result in removing a large fraction of the line emission. Radially, we find that both the gas and dust surface densities can be described by Gaussians, centered at the same disk radius, and with gas profiles wider than for the dust. These results strongly support a scenario in which millimeter dust grains are radially and azimuthally trapped toward the center of a gas pressure bump. Finally, our observations reveal a compact source of continuum and CO emission inside the dust depleted cavity at about 50 AU from the primary star. The kinematics of the CO emission from this region is different from that expected from material in Keplerian rotation around the binary system, and might instead trace a compact disk around a third companion. Higher angular resolution observations are required to investigate the nature of this source.
description: 20 pages, 14 figures, accepted in ApJ
Revealing Hidden Antiferromagnetic Correlations in Doped Hubbard Chains via String Correlators
Creators: name: Hilker, Timon A.
name: Salomon, Guillaume
name: Grusdt, Fabian
name: Omran, Ahmed
name: Boll, Martin
name: Demler, Eugene
name: Bloch, Immanuel
name: Gross, Christian
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Topological phases, like the celebrated Haldane phase in spin-1 chains, defy characterization through local order parameters. Instead, non-local string order parameters can be employed to reveal their hidden order. Similar diluted magnetic correlations appear in doped one-dimensional lattice systems due to the phenomenon of spin-charge separation. Here we report on the direct observation of such hidden magnetic correlations via quantum gas microscopy of hole-doped ultracold Fermi-Hubbard chains. The measurement of non-local spin-density correlation functions reveals a hidden finite-range antiferromagnetic order, a direct consequence of spin-charge separation. Our technique demonstrates how topological order can directly be measured in experiments and it can be extended to higher dimensions to study the complex interplay between magnetic order and density fluctuations.
title: Hadrian als neuer Romulus?: Zum letzten Porträt Kaiser Hadrians
title: Hadrian als neuer Romulus?: Zum letzten Porträt Kaiser Hadrians
titleType: Subtitle
Creators: name: Schröder, Stephan
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Hadrianus
subject: Hadrianus

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease
Creators: name: González-Cuesta, Manuel
name: Herrera-González, Irene
name: García-Moreno, M. Isabel
name: Ashmus, Roger A.
name: Vocadlo, David J.
name: Fernández, José M. García
name: Nanba, Eiji
name: Higaki, Katsumi
name: Mellet, Carmen Ortiz
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences

description: The late-onset form of Tay-Sachs disease displays when the activity levels of human β-hexosaminidase A (HexA) fall below 10% of normal, due to mutations that destabilise the native folded form of the enzyme and impair its trafficking to the lysosome. Competitive inhibitors of HexA can rescue disease-causative mutant HexA, bearing potential as pharmacological chaperones, but often also inhibit the enzyme O-glucosaminidase (GlcNAcase; OGA), a serious drawback for translation into the clinic. We have designed sp2-iminosugar glycomimetics related to GalNAc that feature a neutral piperidine-derived thiourea or a basic piperidine-thiazolidine bicyclic core and behave as selective nanomolar competitive inhibitors of human Hex A at pH 7 with a ten-fold lower inhibitory potency at pH 5, a good indication for pharmacological chaperoning. They increased the levels of lysosomal HexA activity in Tay-Sachs patient fibroblasts having the G269S mutation, the highest prevalent in late-onset Tay-Sachs disease.
Design, synthesis and biological evaluation of novel triazoloquinazolinone and imidazoquinazolinone derivatives as allosteric inhibitors of SHP2 phosphatase
Creators: name: Ye, Wenjun
name: Liu, Ye
name: Ren, Qian
name: Liao, Tianhui
name: Chen, Yumei
name: Chen, Dongmei
name: Wang, Sisi
name: Yao, Lihong
name: Jia, Yihe
name: Zhao, Chunshen
name: Zhou, Zhixu
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: A series of novel triazoloquinolinone and imidazoquinazolinone derivatives were designed and synthesised, and their biological activities against SHP2 protein and melanoma A357 cell line were evaluated in vitro. The results show that some target compounds have moderate to excellent inhibitory activity on SHP2 protein and melanoma A357 cell line. Structure-activity relationships (SARs) showed that both imidazoquinazolinone and triazoloquinazolinone derivatives have good SHP2 protein kinase and melanoma cell line A357 inhibitory activity. The results of molecular docking also showed that the cores of imidazoquinazolinone and triazoloquinazolinone have a certain affinity for SHP2 protein at the same time. Compared with SHP244, the target compounds have quite good liver microsomal stability and has more drug potential. The most promising compound B1 has a strong inhibitory effect on the melanoma cell line A357 at 100 µM (76.15% inhibition).
Additional file 3: of Alcohol marketing on YouTube: exploratory analysis of content adaptation to enhance user engagement in different national contexts
Creators: name: Himanshu Gupta
name: Lam, Tina
name: Pettigrew, Simone
name: Tait, Robert
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: References to the content posted on brandsâ YouTube pages. (DOC 32Â kb)
title: Gestalt und Ausstattung des "Marmorforums" in Mérida : Kenntnisstand und Perspektiven
title: Gestalt und Ausstattung des "Marmorforums" in Mérida : Kenntnisstand und Perspektiven
titleType: Subtitle
Creators: name: Trillmich, Walter
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Mérida (Badajoz)
subject: Mérida (Badajoz)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Challenges for Cosmic-ray Experiments
Creators: name: Gaisser, Thomas
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: This paper is a commentary on presentations at ISVHECRI 2016 related to cosmic rays, gamma rays and neutrinos. Its goal is to highlight the unanswered questions raised during the conference about the sources of these cosmic particles and the relations among them.
description: Based on a summary talk at ISVHECRI 2016, Moscow, August 2016. The paper (8 pages, 8 figures) will be published by EPS Web of Conferences
title: Das Porträt des Miltiades: Zum Wandel des Feldherrnbildnisses im klassischen Athen
title: Das Porträt des Miltiades: Zum Wandel des Feldherrnbildnisses im klassischen Athen
titleType: Subtitle
Creators: name: Hertel, Dieter
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Miltiades
subject: Miltiades

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Eightfold Degenerate Dirac Nodal Line in Collinear Antiferromagnet Mn$_5$Si$_3$
Creators: name: Mendoza-Estrada, Victor
name: González-Hernández, Rafael
name: Uribe, Bernardo
name: Šmejkal, Libor
Publisher: name: arXiv
Year: 2025
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Algebraic Topology (math.AT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We study the electronic, magnetic, and spin transport properties of the orthorhombic Mn$_{5}$Si$_{3}$ compound in the $AF2$ phase using symmetry analysis and ab-initio calculations. Our ground state energy calculations align with experimental observations, demonstrating that the collinear antiferromagnetic (AFM) order, with Néel vector in the [010] direction, is the most stable magnetic configuration both with and without spin-orbit coupling (SOC) in a bulk lattice geometry. We identified an unconventional eight-fold degenerate Dirac nodal line (DNL) close to the Fermi level, characterized by negligible SOC. This DNL is robustly protected by a unique combination of a pure-spin symmetry and a lattice symmetry together with magnetic space group symmetries. Upon introducing SOC, this degeneracy is reduced to two four-fold DNLs, being protected by the combination of time-reversal, partial translation and nonsymmorphic symmetries within the magnetic space group. We predict also a large intrinsic spin Hall conductivity (SHC) which correlates with the presence of SOC-induced splitting of these eight-fold degenerate DNLs near the Fermi level. These intriguing characteristics position collinear antiferromagnet Mn$_{5}$Si$_{3}$ as a compelling candidate for spintronic applications, particularly in the generation and detection of spin currents, while remaining compatible with modern silicon technology.
description: 14 pages, 3 figures
Inverse Protein Folding Problem via Quadratic Programming
Creators: name: Riazanov, Andrii
name: Karasikov, Mikhail
name: Grudinin, Sergei
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: Optimization and Control (math.OC)
subject: FOS: Biological sciences
subject: FOS: Mathematics

description: This paper presents a method of reconstruction a primary structure of a protein that folds into a given geometrical shape. This method predicts the primary structure of a protein and restores its linear sequence of amino acids in the polypeptide chain using the tertiary structure of a molecule. Unknown amino acids are determined according to the principle of energy minimization. This study represents inverse folding problem as a quadratic optimization problem and uses different relaxation techniques to reduce it to the problem of convex optimizations. Computational experiment compares the quality of these approaches on real protein structures.
Local Voting: Optimal Distributed Node Scheduling Algorithm for Multihop Wireless Networks
Creators: name: Vergados, Dimitrios J.
name: Amelina, Natalia
name: Jiang, Yuming
name: Kralevska, Katina
name: Granichin, Oleg
Publisher: name: arXiv
Year: 2017
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: An efficient and fair node scheduling is a big challenge in multihop wireless networks. In this work, we propose a distributed node scheduling algorithm, called Local Voting. The idea comes from the finding that the shortest delivery time or delay is obtained when the load is equalized throughout the network. Simulation results demonstrate that Local Voting achieves better performance in terms of average delay, maximum delay, and fairness compared to several representative scheduling algorithms from the literature. Despite being distributed, Local Voting has a very close performance to a centralized algorithm that is considered to have the optimal performance.
description: Accepted at 2017 INFOCOM Poster and Demo
title: In die Zwischenablage Inscripciones, sacrificios y misterios: el santuario rupestre de Panóias (Portugal): informe preliminar
title: In die Zwischenablage Inscripciones, sacrificios y misterios: el santuario rupestre de Panóias (Portugal): informe preliminar
titleType: Subtitle
Creators: name: Alföldy, Géza
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Panóias (Vila Real, Port.)
subject: Panóias (Vila Real, Port.)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Gel-Based Morphological Design of Zirconium Metal-organic Frameworks
Creators: name: Bueken, Bart
name: Van Velthoven, Niels
name: Willhammar, Tom
name: Stassin, Timothée
name: Stassen, Ivo
name: Keen, David A.
name: Ameloot, Rob
name: Bals, Sara
name: De Vos, Dirk
name: Bennett, Thomas D.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The ability of metal-organic frameworks (MOFs) to gelate under specific synthetic conditions opens up new opportunities in the preparation and shaping of hierarchically porous MOF monoliths, which could be directly implemented for catalytic and adsorptive applications. In this work, we present the first examples of xero- or aerogel monoliths consisting solely of nanoparticles of several prototypical Zr4+-based MOFs: UiO-66-X (X = H, NH2, NO2, (OH)2), UiO-67, MOF-801, MOF-808 and NU-1000. High reactant and water concentrations during synthesis were observed to induce the formation of gels, which were converted to monolithic materials by drying in air or supercritical CO2. Electron microscopy, combined with N2 physisorption experiments, was used to show that an irregular nanoparticle packing leads to pure MOF monoliths with hierarchical pore systems, featuring both intraparticle micropores and interparticle mesopores. Finally, UiO-66 gels were shaped into monolithic spheres of 600 micrometer diameter using an oil-drop method, creating promising candidates for packed-bed catalytic or adsorptive applications, where hierarchical pore systems can greatly mitigate mass transfer limitations.
Exotic phase transition and superconductivity in layered titanium-oxypnictides implied by a computational phonon analysis
Creators: name: Nakano, Kousuke
name: Hongo, Kenta
name: Maezono, Ryo
Publisher: name: arXiv
Year: 2017
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We applied $ab$ $initio$ phonon analysis to layered titanium-oxypnictides, Na$_2$Ti$_2Pn_2$O ($Pn$ = As, Sb), and found a clear contrast between the cases with lighter/heavier pnictogen in comparisons with experiments. The result completely explains the experimental structure, $C$2/$m$ for $Pn$ = As, within the conventional electron-phonon framework, while there arise discrepancies when the pnictogen gets heavier, being in the same trend for the BaTi$_2Pn_2$O ($Pn$ = As, Sb, Bi) case. The fact implies a systematic dependence on pnictogen to tune the mechanism of the phase transition and superconductivity from conventional to exotic.
Additional file 14: Figure S11. of Genomic repeats, misassembly and reannotation: a case study with long-read resequencing of Porphyromonas gingivalis reference strains
Creators: name: Acuña-Amador, Luis
name: Primot, Aline
name: Cadieu, Edouard
name: Roulet, Alain
name: Barloy-Hubler, Frédérique
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Overview of the core genomes of P. gingivalis strains ATCC 33277, TDC60, and W83. a. Pie chart of genes present in all three strains grouped by categories: constant (more than 97% nucleotide identity, none has paralogs); variable (less than 97% nucleotide identity, none have paralogs); with paralogs (at least one strain has paralogs); and with pseudogenisation (at least one strain has a pseudogene, another a functional CDS, and none have paralogs). b. Constant core genes classified into five categories. c. Genes in variable core genome. The 47 genes are presented grouped by function. d. Core genes with paralogs. Gene names and products are listed, and the number of paralogs detailed by strain. To facilitate reading, cells were shaded when at least two paralogs exist. *, pseudogenes; †, a hypothetical gene clustered with genes from the BF0131 conjugative transposon. (PDF 26 kb)
title: Augusteische Brücken in Hispanien: Symbole der "Pax Augusta"
title: Augusteische Brücken in Hispanien: Symbole der "Pax Augusta"
titleType: Subtitle
Creators: name: Nünnerich-Asmus, Annette
Publisher: name: Deutsches Archäologisches Institut
Year: 2020

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
title: Küstenforschung im Ampurdán: Ein Vorbericht
title: Küstenforschung im Ampurdán: Ein Vorbericht
titleType: Subtitle
Creators: name: Marzoli, Dirce
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Empordà, Alt i Baix
subject: Empordà, Alt i Baix

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Design, synthesis, and anti-cancer evaluation of new pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers
Creators: name: Elzahabi, Heba S. A.
name: Nossier, Eman S.
name: Alasfoury, Rania A.
name: El-Manawaty, May
name: Sayed, Sara M.
name: Elkaeed, Eslam B.
name: Metwaly, Ahmed M.
name: Hagras, Mohamed
name: Eissa, Ibrahim H.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: A new series of pyrido[2,3-d]pyrimidin-4(3H)-one derivatives having the essential pharmacophoric features of EGFR inhibitors has been designed and synthesised. Cell viability screening was performed for these compounds against A-549, PC-3, HCT-116, and MCF-7 cell lines at a dose of 100 μM. The highest active derivatives (8a, 8 b, 8d, 9a, and 12b) were selected for IC50 screening. Compounds 8a, 8 b, and 9a showed the highest cytotoxic activities and were further investigated for wild EGFRWT and mutant EGFRT790M inhibitory activities. Compound 8a showed the highest inhibitory activities against EGFRWT and EGFRT790M with IC50 values of 0.099 and 0.123 µM, respectively. In addition, it arrested the cell cycle at pre-G1 phase and induced a significant apoptotic effect in PC-3 cells. Furthermore, compound 8a induced a 5.3-fold increase in the level of caspase-3 in PC-3 cells. Finally, docking studies were carried out to examine the binding mode of the synthesised compounds against both EGFRWT and EGFRT790M.
Jet schemes of quasi-ordinary surface singularities
Creators: name: Cobo, Helena
name: Mourtada, Hussein
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14E18, 14J17

description: In this paper we give a complete description of the irreducible components of the jet schemes (with origin in the singular locus) of a two-dimensional quasi-ordinary hypersurface singularity. We associate with these components and with their codimensions and embedding dimensions, a weighted graph. We prove that the data of this weighted graph is equivalent to the data of the topological type of the singularity. We also determine a component of the jet schemes (or equivalently, a divisor on $\mathbb{A}^3$), that computes the log canonical threshold of the singularity embedded in $\mathbb{A}^3$. This provides us with pairs $X\subset\mathbb{A}^3$ whose log canonical thresholds are not contributed by monomial divisorial valuations. Note that for a pair $C\subset\mathbb{A}^2$, where $C$ is a plane curve, the log canonical threshold is always contributed by a monomial divisorial valuation (in suitable coordinates of $\mathbb{A}^2$).
title: Holozäne Küstenlinie am Unterlauf des río Guadalquivir zwischen Sevilla und der Mündung in den Atlantik
title: Holozäne Küstenlinie am Unterlauf des río Guadalquivir zwischen Sevilla und der Mündung in den Atlantik
titleType: Subtitle
Creators: name: Schulz, Horst
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Guadalquivir, río
subject: Guadalquivir, río

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Design and synthesis of some new benzoylthioureido phenyl derivatives targeting carbonic anhydrase enzymes
Creators: name: Najm, Mazin A. A.
name: Mahmoud, Walaa R.
name: Taher, Azza T.
name: Abbas, Safinaz E-S.
name: Awadallah, Fadi M.
name: Allam, Heba Abdelrasheed
name: Vullo, Daniela
name: Supuran, Claudiu T.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Medicine
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The present study aimed to develop potent carbonic anhydrase inhibitors (CAIs). The design of the target compounds was based on modifying the structure of the ureido-based carbonic anhydrase inhibitor SLC-0111. Six series of a substituted benzoylthioureido core were prepared featuring different zinc-binding groups; the conventional sulphamoyl group 4a–d and 12a–c, its bioisosteric carboxylic acid group 5a–d and 13a–c or the ethyl carboxylate group 6a–d and 14a–c as potential prodrugs. All compounds were assessed for their carbonic anhydrase (CA) inhibitory activity against a panel of four physiologically relevant human CA isoforms hCA I and hCA II, and hCA IX, and hCA XII. Compounds 4a, 4b, 4c, 4d, 5d, 12a, and 12c revealed significant inhibitory activity against hCA I that would highlight these compounds as promising drug candidates for the treatment of glaucoma.
Additional file 5: of Functional health state description and valuation by people aged 65 and over: a pilot study
Creators: name: Riaan Botes
name: Vermeulen, Karin
name: Adelita Ranchor
name: Buskens, Erik
Publisher: name: figshare
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: TTO example. Example of the Time Trade Off method utilized in the study. (DOCX 11Â kb)
Gradual Regime Shifts in Fairy Circles
Creators: name: Zelnik, Yuval R.
name: Meron, Ehud
name: Bel, Golan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Large responses of ecosystems to small changes in the conditions--regime shifts--are of great interest and importance. In spatially extended ecosystems, these shifts may be local or global. Using empirical data and mathematical modeling, we investigated the dynamics of the Namibian fairy circle ecosystem as a case study of regime shifts in a pattern-forming ecosystem. Our results provide new support, based on the dynamics of the ecosystem, for the view of fairy circles as a self-organization phenomenon driven by water-vegetation interactions. The study further suggests that fairy circle birth and death processes correspond to spatially confined transitions between alternative stable states. Cascades of such transitions, possible in various pattern-forming systems, result in gradual rather than abrupt regime shifts.
title: Geoarchäologische Forschungen im Umkreis der Marismas am río Guadalquivir (Niederandalusien)
title: Geoarchäologische Forschungen im Umkreis der Marismas am río Guadalquivir (Niederandalusien)
titleType: Subtitle
Creators: name: Arteaga, Oswaldo
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Guadalquivir, río
subject: Guadalquivir, río

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Additional file 4 of CoSTA: unsupervised convolutional neural network learning for spatial transcriptomics analysis
Creators: name: Xu, Yang
name: McCord, Rachel Patton
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 4. Supplementary Fig. 4: Training CoSTA with different ratios of SE and non-SE genes. (A) To simulate non-SE genes, five patterns without clear spatial features were used. (B) Simulated non-SE genes were mixed with SE genes simulated from the 5 patterns in Figure 1 in different ratios from 90:10 to 10:90. CoSTA representations of these gene mixtures are visualized in 2D UMAP. Genes are colored based on pattern membership (top) or SE type (bottom). (C) Silhouette scores quantify how well the representation distinguishes different patterns for SE and non-SE genes across different mixture ratios.
title: Die nacheiszeitliche Landschaftsentwicklung der andalusischen Mittelmeerküste am Beispiel der phönizischen Niederlassung Sexi (Almuñécar)
title: Die nacheiszeitliche Landschaftsentwicklung der andalusischen Mittelmeerküste am Beispiel der phönizischen Niederlassung Sexi (Almuñécar)
titleType: Subtitle
Creators: name: Hoffmann, Gerd
Publisher: name: Deutsches Archäologisches Institut
Year: 2020

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
title: Eine "Dendrochronologische Datenbank für die Iberische Halbinsel": Grundlagen und Möglichkeiten
title: Eine "Dendrochronologische Datenbank für die Iberische Halbinsel": Grundlagen und Möglichkeiten
titleType: Subtitle
Creators: name: Pingel, Volker
name: Richter, Klaus
Publisher: name: Deutsches Archäologisches Institut
Year: 2020

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
title: Forschungsprobleme der Archäozoologie auf der Iberischen Halbinsel
title: Forschungsprobleme der Archäozoologie auf der Iberischen Halbinsel
titleType: Subtitle
Creators: name: Uerpmann, Margarethe
Publisher: name: Deutsches Archäologisches Institut
Year: 2020

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Additional file 2: of Alcohol marketing on YouTube: exploratory analysis of content adaptation to enhance user engagement in different national contexts
Creators: name: Himanshu Gupta
name: Lam, Tina
name: Pettigrew, Simone
name: Tait, Robert
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Types of strategies identified on the top 20 alcohol brands with the greatest YouTube presence, 10 each for India and Australia. (DOC 74Â kb)
Delay-time distribution in the scattering of time-narrow wave packets. (I)
Creators: name: Smilansky, Uzy
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: This is the first of two subsequent publications where the probability distribution of delay-times in scattering of wave packets is discussed. The probability distribution is expressed in terms of the on-shell scattering matrix, the dispersion relation of the scattered beam and the wave packet envelope. In the monochromatic limit (poor time resolution) the mean delay-time coincides with the expression derived by Eisenbud and Wigner and generalized by Smith more than half a century ago. In the opposite limit, and within the semi-classical approximation, the resulting distribution coincides with the result obtained using classical mechanics or geometrical optics. The general expression interpolates smoothly between the two extremes. An application for the scattering of electromagnetic waves in networks of RF transmission lines will be discussed in the next paper to illustrate the method in an experimentally relevant context.
Dynamics of a stochastic excitable system with slowly adapting feedback
Creators: name: Franović, Igor
name: Yanchuk, Serhiy
name: Eydam, Sebastian
name: Bačić, Iva
name: Wolfrum, ##!Error: Attribute  Unknown!##
Publisher: name: Weierstrass Institute
Year: 2020
Subjects: subject: Excitability
subject: adaption
subject: coherence resonance
subject: 89.75.Fb
subject: 05.40.Ca

description: We study an excitable active rotator with slowly adapting nonlinear feedback and noise. Depending on the adaptation and the noise level, this system may display noise-induced spiking, noise-perturbed oscillations, or stochastic busting. We show how the system exhibits transitions between these dynamical regimes, as well as how one can enhance or suppress the coherence resonance, or effectively control the features of the stochastic bursting. The setup can be considered as a paradigmatic model for a neuron with a slow recovery variable or, more generally, as an excitable system under the influence of a nonlinear control mechanism. We employ a multiple timescale approach that combines the classical adiabatic elimination with averaging of rapid oscillations and stochastic averaging of noise-induced fluctuations by a corresponding stationary Fokker-Planck equation. This allows us to perform a numerical bifurcation analysis of a reduced slow system and to determine the parameter regions associated with different types of dynamics. In particular, we demonstrate the existence of a region of bistability, where the noise-induced switching between a stationary and an oscillatory regime gives rise to stochastic bursting.
Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
Creators: name: Ibáñez-Escribano, Alexandra
name: Fonseca-Berzal, Cristina
name: Martínez-Montiel, Mónica
name: Álvarez-Márquez, Manuel
name: Gómez-Núñez, María
name: Lacueva-Arnedo, Manuel
name: Espinosa-Buitrago, Teresa
name: Martín-Pérez, Tania
name: Escario, José Antonio
name: Merino-Montiel, Penélope
name: Montiel-Smith, Sara
name: Gómez-Barrio, Alicia
name: López, Óscar
name: Fernández-Bolaños, José G.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Physical Sciences not elsewhere classified
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Virology

description: Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evaluated towards Trypanosoma cruzi and Trichomonas vaginalis. Thiosemicarbazide 31 showed the best trypanocidal profile (epimastigotes), similar to benznidazole (BZ): IC50 (31)=28.72 μM (CL-B5 strain) and 33.65 μM (Y strain), IC50 (BZ)=25.31 μM (CL-B5) and 22.73 μM (Y); it lacked toxicity over mammalian cells (CC50 > 256 µM). Thiosemicarbazones 49, 51 and 63 showed remarkable trichomonacidal effects (IC50 =16.39, 14.84 and 14.89 µM) and no unspecific cytotoxicity towards Vero cells (CC50 ≥ 275 µM). Selenoisosters 74 and 75 presented a slightly enhanced activity (IC50=11.10 and 11.02 µM, respectively). Hydrogenosome membrane potential and structural changes were analysed to get more insight into the trichomonacidal mechanism.
title: Zur Technik der Goldflaschen aus dem bronzezeitlichen Schatzfund von Villena (Alicante)
title: Zur Technik der Goldflaschen aus dem bronzezeitlichen Schatzfund von Villena (Alicante)
titleType: Subtitle
Creators: name: Armbruster, Barbara Regine
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Villena (Alicante)
subject: Villena (Alicante)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
First constraints on the magnetic field strength in extra-Galactic stars: FORS2 observations of Of?p stars in the Magellanic Clouds
Creators: name: Bagnulo, S.
name: Naze, Y.
name: Howarth, I. D.
name: Morrell, N.
name: Vink, J. S.
name: Wade, G. A.
name: Walborn, N.
name: Romaniello, M.
name: Barba, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Massive O-type stars play a dominant role in our Universe, but many of their properties remain poorly constrained. In the last decade magnetic fields have been detected in all Galactic members of the distinctive Of?p class, opening the door to a better knowledge of all O-type stars. With the aim of extending the study of magnetic massive stars to nearby galaxies, to better understand the role of metallicity in the formation of their magnetic fields and magnetospheres, and to broaden our knowledge of the role of magnetic fields in massive star evolution, we have carried out spectropolarimetry of five extra-Galactic Of?p stars, as well as a couple of dozen neighbouring stars. We have been able to measure magnetic fields with typical error bars from 0.2 to 1.0 kG, depending on the apparent magnitude and on weather conditions. No magnetic field has been firmly detected in any of our measurements, but we have been able to estimate upper limits to the field values of our target stars. One of our targets, 2dFS 936, exhibited an unexpected strengthening of emission lines. We confirm the unusual behaviour of BI 57, which exhibits a 787 d period with two photometric peaks and one spectroscopic maximum. The observed strengthening of the emission lines of 2dFS 936, and the lack of detection of a strong magnetic field in a star with such strong emission lines is at odd with expectations. Together with the unusual periodic behaviour of BI 57, it represents a challenge for the current models of Of?p stars. The limited precision that we obtained in our field measurements (in most cases as a consequence of poor weather) has led to field-strength upper limits that are substantially larger than those typically measured in Galactic magnetic O stars. Further higher precision observations and monitoring are clearly required.
description: Accepted by A&A
title: Fuente Alamo: Eine bronzezeitliche Höhensiedlung in Andalusien
title: Fuente Alamo: Eine bronzezeitliche Höhensiedlung in Andalusien
titleType: Subtitle
Creators: name: Schubart, Hermanfrid
name: Pingel, Volker
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Fuente Álamo (Cuevas del Almanzora, Almería)
subject: Fuente Álamo (Cuevas del Almanzora, Almería)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M
Creators: name: Aboelez, Moustafa O.
name: Belal, Amany
name: Xiang, Guangya
name: Ma, Xiang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer

description: A new class of EGFR PROTACs based on pomalidomide was developed, synthesised, and tested for their cytotoxic activity against a panel of human cancer cells. Compounds 15–21 were showed to be more effective against the four tested cell lines than erlotinib. In particular, compound 16 was found to be the most potent counterpart as it was 5.55, 4.34, 5.04, and 7.18 times more active than erlotinib against MCF-7, HepG-2, HCT-116, and A549 cells, respectively. Compound 15 was revealed to be more active than doxorubicin against the four tested cell lines. Furthermore, the most potent cytotoxic compounds were studied further for their kinase inhibitory effects against EGFRWT and EGFRT790M using HTRF test. Compound 16 showed to be the most effective against both kinds of EGFR, with IC50 values of 0.10 and 4.02 µM, respectively. Compound 16 could effectively degrade EGFR protein through ubiquitination (Dmax = 96%) at 72 h in the tested cells.
title: Zylindrische Gefässe, Kerbblattverzierung und Glockenbecher in Zambujal (Portugal): Ein Beitrag zur kupferzeitlichen Keramikchronologie
title: Zylindrische Gefässe, Kerbblattverzierung und Glockenbecher in Zambujal (Portugal): Ein Beitrag zur kupferzeitlichen Keramikchronologie
titleType: Subtitle
Creators: name: Kunst, Michael
Publisher: name: Deutsches Archäologisches Institut
Year: 2020
Subjects: subject: Zambujal (Torres Vedras, Lisboa, Port.)
subject: Zambujal (Torres Vedras, Lisboa, Port.)

description: Madrider Mitteilungen, Vol. 36 (1995)
description: Deutsche Zusammenfassung folgt.
Design and development of a software system for swarm intelligence based research studies
Creators: name: Kose, Utku
Publisher: name: arXiv
Year: 2017
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: This paper introduce a software system including widely-used Swarm Intelligence algorithms or approaches to be used for the related scientific research studies associated with the subject area. The programmatic infrastructure of the system allows working on a fast, easy-to-use, interactive platform to perform Swarm Intelligence based studies in a more effective, efficient and accurate way. In this sense, the system employs all of the necessary controls for the algorithms and it ensures an interactive platform on which computer users can perform studies on a wide spectrum of solution approaches associated with simple and also more advanced problems.
description: 6 pages, 2 figures, 1 table