cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: 01_2875
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Survival and tumour control probability in tumours with heterogeneous oxygenation: A comparison between the linear-quadratic and the universal survival curve models for high doses
Creators: name: Lax, Ingmar
name: Toma-Dasu, Iuliana
name: Lindblom, Emely
name: Dasu, Alexandru
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Hematology
subject: Cancer
subject: Mathematics
subject: FOS: Mathematics
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Cell Biology
subject: Medicine
subject: Biophysics

description: Background. The validity of the linear-quadratic (LQ) model at high doses has been questioned due to a decreasing agreement between predicted survival and experimental cell survival data. A frequently proposed alternative is the universal survival curve (USC) model, thought to provide a better fit in the high-dose region. The comparison between the predictions of the models has mostly been performed for uniform populations of cells with respect to sensitivity to radiation. This study aimed to compare the two models in terms of cell survival and tumour control probability (TCP) for cell populations with mixed sensitivities related to their oxygenation.Methods. The study was performed in two parts. For the first part, cell survival curves were calculated with both models assuming various homogeneous populations of cells irradiated with uniform doses. For the second part, a realistic three-dimensional (3D) model of complex tumour oxygenation was used to study the impact of the differences in cell survival on the modelled TCP. Cellular response was assessed with the LQ and USC models at voxel level and a Poisson TCP model at tumour level.Results. For hypoxic tumours, the disputed continuous bend of the LQ survival curve was counteracted by the increased radioresistance of the hypoxic cells and the survival curves started to diverge only at much higher doses than for oxic tumours. This was also reflected by the TCP curves for hypoxic tumours for which the difference in D50 values for the LQ and USC models was reduced from 5.4 to 0.2 Gy for 1 and 3 fractions, respectively, in a tumour with only 1.1% hypoxia and from 9.5 to 0.4 Gy in a tumour with 11.1% hypoxia.Conclusions. For a large range of fractional doses including hypofractionated schemes, the difference in predicted survival and TCP between the LQ and USC models for tumours with heterogeneous oxygenation was found to be negligible.
Heart (Medical illustrations)
Creators: name: Francone, Clarice Ashworth
Publisher: name: Oregon Health & Science University
Year: 0
Subjects: Medical Illustration
Heart
Coronary Circulation
Heart Ventricles
Muscle Contraction

description: 25 pencil sketches of the heart in both black and white and in color. Includes diagrams illustrating blood flow, labeled drawings of the different parts of the heart, its place within the ribcage and its muscles.
title: Burumai
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Kakoro Bibi tells the story of his ancestor, Burumai
title: 02_0418
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
The effect of a chronic Toxoplasma gondii infection on acquired brain injuries and epilepsy in mice
Creators: name: BAKER, TAMARA LEXIE
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 320999
subject: Neurosciences not elsewhere classified

description: Traumatic brain injury (TBI) and mesial temporal lobe epilepsy (MTLE) are common neurological conditions, and neuroinflammation can alter long-term patient outcomes. However, infection can influence this biological process. As such, clinically relevant and common infections, such as the parasite Toxoplasma gondii, should be studied. T. gondii chronically and incurably infects one-third globally. Therefore, this thesis aimed to investigate the impact of a chronic T. gondii infection on TBI and MTLE in male and female mice. Overall, T. gondii worsened neuroinflammation, brain damage and behavioral measures following TBI and MTLE models. T. gondii also increased seizure susceptibility and promoted epilepsy development.
title: Gazette SHCC, cycle 6, Modernité, séance du 25 novembre 2009
Creators: name: Schmidt, Nicolas
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Relation: http://purl.org/poi/crdo.vjf.cnrs.fr/cocoon-92238756-8f2d-4702-a387-568f2d8702e3
Francesco de Martino & Carmen Morenilla (eds.). Teatro y Sociedad en la Antigüedad Clásica. A la sombra de los héroes. Levante Editori, Bari, 2014, 486 pp. ISBN: 978-88-7949-638-4
Creators: name: Molina Muñoz, Pedro Jesús
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2015

description: La presente obra, titulada “A la sombra de los héroes”, volumen decimoséptimo de la colección El teatro clásico en el marco de la cultura griega y su pervivencia en la cultura occidental, editada por los profesores De Martino y Morenilla, recoge las investigaciones realizadas con ocasión del XVII Congreso Internacional de Teatro Grecolatino y su pervivencia en la cultura occidental, organizado por el Grup de Recerca i Acció Teatral de la Universitat de València. El presente volumen dedica su atención a los personajes secundarios y está dividido en dos partes: la primera, dedicada al teatro grecolatino; y la segunda, dedicada a su tradición clásica y recepción en la cultura occidental. Supone un acercamiento a las relaciones que los personajes secundarios mantienen con los protagonistas y aporta valiosas conclusiones al estudio de unos personajes cuya relevancia en la escena teatral no ha sido siempre valorada, a pesar de su importancia para el desarrollo de la trama e incluso para el espectáculo mismo de las obras. (...)
description: Ágora. Estudos Clássicos em Debate, n.º 17 (2015)
title: Amo di bio mutire pi daba
title: Counting like the ancestors
titleType: AlternativeTitle
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Eramiri explains how the ancestors used to count the days
Automated tracking and species classification of ecological communities
Creators: name: Besson, Marc
name: Gilliot, Pierre-Aurélien M.A.
name: Gorochowski, Thomas E.
name: Clements, Christopher F.
Publisher: name: Zenodo
Year: 2021

description: Abstract and Presentation for the British Ecological Society and the Société Française d’Écologie et d’Évolution joint conference (Ecology Across Border 2021).
Assessment of volume segmentation in radiotherapy of adolescents; a treatment planning study by the Swedish Workgroup for Paediatric Radiotherapy
Creators: name: Nilsson, Kristina
name: Taheri-Kadkhoda, Zahra
name: Lindh, Jack
name: Nilsson, Per
name: Kristensen, Ingrid
name: Agrup, Måns
name: Bergström, Per
name: Engellau, Jacob
name: Haugen, Hedda
name: Martinsson, Ulla
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Medicine
subject: Engineering

description: Background and purpose. The variability in target delineation for similar cases between centres treating paediatric and adolescent patients, and the apparent differences in interpretation of radiotherapy guidelines in the treatment protocols encouraged us to perform a dummy-run study as a part of our quality assurance work. The aim was to identify and quantify differences in the segmentation of target volumes and organs at risk (OARs) and to analyse the treatment plans and dose distributions. Materials and methods. Four patient cases were selected: Wilm's tumour, Hodgkin's disease, rhabdomyosarcoma of the prostate and chordoma of the skull base. The five participating centres received the same patient-related material. They introduced the cases in their treatment planning system, delineated target volumes and OARs and created treatment plans. Dose-volume histograms were retrieved for relevant structures and volumes and dose metrics were derived and compared, e.g. target volumes and their concordance, dose homogeneity index (HI), treated and irradiated volumes, remaining volume at risk and relevant Vx and Dx values. Results. We found significant differences in target segmentation in the majority of the cases. The planning target volumes (PTVs) varied two- to four-fold and conformity indices were in the range of 0.3–0.6. This resulted in large variations in dose distributions to OARs as well as in treated and irradiated volumes even though the treatment plans showed good conformity to the PTVs. Potential reasons for the differences in target delineation were analysed. Conclusion. Considerations of the growing child and difficulties in interpretation of the radiotherapy information in the treatment protocols were identified as reasons for the variation. As a result, clarified translated detailed radiotherapy guidelines for paediatric/adolescent patients have been recognised as a way to reduce this variation.
Accurate prostate tumour detection with multiparametric magnetic resonance imaging: Dependence on histological properties
Creators: name: Diest, Paul J. Van
name: Philippens, Marielle E. P.
name: Borren, Alie
name: Groenendaal, Greetje
name: Moman, Maaike R.
name: Kruger, Arto E. Boeken
name: Vulpen, Marco Van
name: Uulke A. Van Der Heide
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Cancer
Biological Sciences
Cell Biology
Medicine
Engineering

description: Background. To benefit most of focal treatment of prostate tumours, detection with high precision of all tumour voxels is needed. Although diffusion-weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) have good diagnostic performance, perfect tumour detection is challenging. In this study, we investigated the variation in prostate tissue characteristics Gleason score (GS), cell density (CD) and microvessel density (MVD) to explain the limitations in tumour voxel detection with a MRI-based logistic regression model. Material and methods. Twelve radical prostatectomy patients underwent a pre-operative 3.0T DWI and DCE-MRI exam. The MRI scans were used to calculate voxel-wise tumour probability with a logistic regression model for the peripheral zone (PZ) of the prostate. Tumour probability maps were correlated and validated with whole-mount histology. Additionally, from the whole-mount histological sections CD, MVD and GS were retrieved for every single voxel. GS, CD and MVD of true- and false-positive voxels and of true- and false-negative voxels were compared using Mann-Whitney U-tests. Results. False-negative tumour voxels had significantly lower CD and MVD (p < 0.0001) and were similar to non-tumour PZ. True-positive detected tumour voxels had high CDs and MVDs (p < 0.0001). In addition, tumour voxels with higher GS showed a trend towards more frequent detection (p = 0.06). Tumour voxels with GS ≥ 3 + 4 showed higher CD and MVD compared to tumour voxels with GS 3 + 3 (p < 0.0001). Conclusion. Tumour voxels with low CD and MVD resemble healthy tissue and are limiting tumour voxel detection using DWI and DCE-MRI. Nevertheless, the most aggressive tumour voxels, containing high CD, MVD and GS, are more likely to be detected and can therefore be treated with high dose using focal therapy or focal boosting.
Joaquín GARCÍA NISTAL (coord.), Imagen y documento: materiales para escribir una historia cultural, León, Eds. El Forastero (Lobo Sapiens), 2014, 324 pp., ISBN: 978-84-942791-0-2
Creators: name: Alonso Romo, Eduardo Javier
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2015

description: Como es sabido, la historia cultural es la denominación de una corriente historiográfica, más que una disciplina en sí misma. Comenzó a utilizarse hace ya varias décadas, sobre todo para definir determinados trabajos de historiadores anglófonos y francófonos. La historia cultural combina diversos enfoques y metodologías, que pueden ir desde lo filológico a la historia del arte, pasando por la archivística, la antropología, la cultura material o la historia de las mentalidades. Pues bien, es en este contexto donde cobra pleno sentido el estudio conjugado de la imagen y el documento desde análisis interdisciplinares. (...)
description: Ágora. Estudos Clássicos em Debate, n.º 17 (2015)
Carmen SOARES (Coord.), Espaços do pensamento científico da Antiguidade, Coimbra, Imprensa da Universidade de Coimbra, 2013, 98 pp. [ISBN 978-989-26-0743-6]
Creators: name: Mora, Carlos De Miguel
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2015

description: Este livro constitui o primeiro número de uma coleção que, sob o título de Conferências & Debates Interdisciplinares, tenciona promover aquela que é a missão do Instituto de Investigação Interdisciplinar da Universidade de Coimbra, isto é, o estímulo de uma investigação alicerçada no cruzamento de áreas de saber distintas. O denominador comum que hão de possuir os volumes que integrarão a coleção será o diálogo entre diferentes domínios científicos. (...)
description: Ágora. Estudos Clássicos em Debate, n.º 17 (2015)
Miguel ALARCOS MARTÍNEZ, Virgilio y su reelaboración cervantina en el Persiles: hacia una aproximación inmanente. Vigo, Editorial Académica del Hispanismo, 2014, 321 pp. [ISBN: 978-84-15175-83-4]
Creators: name: Baeza Angulo, Eulogio
Publisher: name: Ágora. Estudos Clássicos em Debate
Year: 2015

description: Este libro de Miguel Alarcos Martínez es la versión revisada de una parte de su tesis doctoral, defendida en la Universidad de Oviedo en 2011. La monografía se propone, como se desprende evidentemente del propio título, el ambicioso proyecto de estudiar, desde un punto de vista inmanente, la influencia de Virgilio y su reelaboración cervantina en Los trabajos de Persiles y Segismunda. El trabajo, tras un “Prólogo” (pp. 17-19) a cargo de Alberto Blecua, seguido de una no breve “Introducción” programática (pp. 21-32), se divide en doce capítulos, culminados con la “Bibliografía citada y tematizada” (pp. 303-310) y dos índices, “Índice léxico-temático de materias (y conceptos)” (pp. 311-316) e “Índice de onomásticas destacadas (Autores y Obras de Crítica y Creación, Personajes literarios & espacios ficcionales)” (pp. 317-321). (...)
description: Ágora. Estudos Clássicos em Debate, n.º 17 (2015)
title: Making powder aerosol deposition accessible for small amounts : A novel and modular approach to produce dense ceramic films
Creators: name: Exner, Jörg
name: Linz, Mario
name: Kita, Jaroslaw
name: Moos, Ralf
Publisher: name: University of Bayreuth
Year: 2021
Subjects: subject: ceramic cold processing
subject: ceramic spray coating
subject: miniaturized deposition device
subject: optical transmittance
subject: spot deposition
subject: 620

description: Powder aerosol deposition is a promising technique to deposit dense ceramic films directly at room temperature. While previous developments pointed towards larger and more complex deposition devices, this work follows a different approach and proposes a simplified and miniaturized coating device (denoted as Micro-PAD, µPAD). The aim is twofold: creating a smaller and flexible device consisting of an aerosol generation unit and a deposition chamber with a combined low areal footprint of 30 cm by 20 cm (that, e.g., easily fits in a glove box) as well as lowering the hurdle for other researchers to use the powder aerosol deposition. Therefore, we introduce a device mainly based on commercially available components/connectors as well as manual operated valves/flow meters. A key point is the elimination of moving components by just using a spot deposition that was enabled by using a circular de-Laval-type nozzle.The operational capability of µPAD is proven for the deposition of alumina films and compared to conventional PAD in terms of mechanical, crystalline, and optical film properties. Thick films with a bell-shape-like profile are deposited by µPAD, featuring a plateau in the center of the film with a diameter of 5 mm and a FWHM (full width at half maximum) diameter of about 10 mm. Alumina films produced by µPAD do not only match the properties of corresponding PAD films, but oftentimes outperform them. Here, µPAD films exhibit increased hardness and optical transmittance values, surpassing reference values of the conventional sprayed counterparts by at least 10%. Also, film integrity and adhesion to the substrate are slightly higher in case of µPAD. Reasons for the improved film properties are found by X-ray diffraction, with a significantly higher fracturing of impacting particles during µPAD combined with improved film consolidation as observed by SEM. Furthermore, µPAD featured doubled to tripled the deposition rates and, markedly almost doubled the deposition efficiency.
Rapid reduction in the incidence of cancer of unknown primary. A population-based study
Creators: name: Brustugun, Odd Terje
name: Helland, Åslaug
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Biotechnology

description: Background. Cancer of unknown primary (CUP) carries a dismal prognosis due to the two hallmarks of 1) being metastatic with 2) no known specific treatment. An organ-labeled diagnosis of cancer should therefore be sought. In this study, we have analyzed population-based incidence and survival data of CUP over the latest 40 years. Material and methods. Complete national data on 23 004 CUP-patients from the Cancer Registry of Norway sampled from 1971 to 2010 are presented, with absolute and age-adjusted incidence rates correlated to the total cancer incidence. One-year relative survival rates were calculated. Results. The incidence of CUP increased both in absolute numbers and as a fraction of total cancer incidence during the first half of the period. There has been a substantial decrease in incidence over the latest 20 years, now being responsible of only 1.7% and 1.2% of the total cancer incidence in females and males, respectively, with an age-adjusted incidence rate of 3.5 and 3.8, respectively. The one-year relative survival rate has increased and was slightly below 20% for both sexes in 2010. Conclusion. Better diagnostics, both radiological and pathological, is probably responsible for a substantially lower incidence. Improved treatment for cancers in general also benefits the CUP-group.
Dose-adapted salvage radiotherapy after radical prostatectomy based on an erMRI target definition model: Toxicity analysis
Creators: name: Zilli, Thomas
name: Jorcano, Sandra
name: Peguret, Nicolas
name: Caparrotti, Francesca
name: Hidalgo, Alberto
name: Haleem G. Khan
name: Hansjorg Vees
name: Weber, Damien C.
name: Miralbell, Raymond
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Pharmacology
subject: Cell Biology
subject: Microbiology
subject: FOS: Biological sciences

description: Background. To assess treatment tolerance by patients treated with a dose-adapted salvage radiotherapy (SRT) protocol based on an multiparametric endorectal magnetic resonance imaging (erMRI) failure definition model after radical prostatectomy (RP). Material and methods. A total of 171 prostate cancer patients recurring after RP undergoing erMRI before SRT were analyzed. A median dose of 64 Gy was delivered to the prostatic bed (PB) with, in addition, a boost of 10 Gy to the suspected relapse as visualized on erMRI in 131 patients (76.6%). Genitourinary (GU) and gastrointestinal (GI) toxicities were scored using the RTOG scale. Results. Grade ≥ 3 GU and GI acute toxicity were observed in three and zero patients, respectively. The four-year grade ≥ 2 and ≥ 3 late GU and GI toxicity-free survival rates (109 patients with at least two years of follow-up) were 83.9 ± 4.7% and 87.1 ± 4.2%, and 92.1 ± 3.6% and 97.5 ± 1.7%, respectively. Boost (p = 0.048) and grade ≥ 2 acute GU toxicity (p = 0.008) were independently correlated with grade ≥ 2 late GU toxicity on multivariate analysis. Conclusions. A dose-adapted, erMRI-based SRT approach treating the PB with a boost to the suspected local recurrence may potentially improve the therapeutic ratio by selecting patients that are most likely expected to benefit from SRT doses above 70 Gy as well as by reducing the size of the highest-dose target volume. Further prospective trials are needed to investigate the use of erMRI in SRT as well as the role of dose-adapted protocols and the best fractionation schedule.
Accuracy of 18F-FDG PET/CT for primary tumor visualization and staging in T1 breast cancer
Creators: name: Rutgers, Emiel J. Th.
name: Koolen, Bas B.
name: Leij, Femke Van Der
name: Vogel, Wouter V.
name: Marie-Jeanne T. F. D. Vrancken Peeters
name: Elkhuizen, Paula H. M.
name: Olmos, Renato A. Valdés
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Biological Sciences
subject: Cell Biology
subject: Medicine
subject: Engineering

description: Background. The aim of this study was to assess the accuracy of 18F-FDG PET/CT in T1 breast cancer regarding visualization of the primary tumor and the detection of locoregional and distant metastases. Methods. Sixty-two women with invasive T1 breast cancer underwent a PET/CT. Image acquisition of the thorax was done in prone position with hanging breasts, followed by whole-body scanning in supine position. Primary tumor FDG uptake was evaluated and compared with clinical and histopathological characteristics. Presence of locoregional and distant metastases was assessed and compared with conventional imaging procedures. Results. The primary tumor was visible with PET/CT in 54 (87%) of 62 patients, increasing from 59% (10/17) in tumors ≤ 10 mm to 98% (44/45) in tumors over 10 mm. All triple negative and HER2-positive tumors and 40/48 (83%) ER-positive/HER2-negative tumors were visualized. Sensitivity and specificity of PET/CT in the detection of axillary metastases were 73% and 100%, respectively. PET/CT depicted periclavicular nodes in two patients. Of 12 distant lesions, one was confirmed to be a lung metastasis, three were false positive, and eight were new primary proliferative lesions. Conclusion. Using optimal imaging acquisition, the majority of T1 breast carcinomas can be visualized with PET/CT. Specificity in the detection of axillary metastases is excellent, but sensitivity appears to be limited. Additional whole body imaging has a low yield in this specific patient group.
title: 03_0531
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Inhomogeneous dose escalation increases expected local control for NSCLC patients with lymph node involvement without increased mean lung dose
Creators: name: Nielsen, Tine B.
name: Olfred Hansen
name: Schytte, Tine
name: Brink, Carsten
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Hematology
subject: Cancer
subject: Biological Sciences
subject: Physiology
subject: Molecular Biology
subject: Cell Biology
subject: Medicine
subject: Physics
subject: Biophysics

description: Background. Higher doses to NSCLC tumours are required to increase the low control rates obtained with conventional dose prescriptions. This study presents the concept of inhomogeneous dose distributions as a general way to increase local control probability, not only for isolated lung tumours but also for patients with involved lymph nodes. Material and methods. Highly modulated IMRT plans with homogeneous dose distributions with a prescribed dose of 66Gy/33F were created for 20 NSCLC patients, staged T1b-T4 N0-N3, using standard PTV dose coverage of 95–107%. For each patient, an inhomogeneous dose distribution was created with dose constraints of: PTV-coverage ≥ 95%, same mean lung dose as obtained in the homogeneous dose plan, maximum doses of 45 and 66 Gy to spinal canal and oesophagus, respectively, and V74Gy < 1 cm3 for each of: aorta, trachea + bronchi, the connective tissue in mediastinum, and the thorax wall. The dose was escalated using a TCP model implemented into the planning system. The difference in TCP values between the homogeneous and inhomogeneous plans were evaluated using two different TCP models. Results. Dose escalation was possible for all patients. TCP values based on assumed homogeneous distribution of clonogenic cells either in the GTV, CTV or PTV showed absolute TCP increases of approximately 15, 10 and 5 percentage points, respectively. This increase in local control was obtained without increasing the mean lung dose. However, small increases in maximum doses to the mediastinum were observed: 2.5 Gy for aorta, 4.4 Gy for the connective tissue, 1.6 Gy for the heart, and 2.6 Gy for trachea + bronchi. Conclusion. Increased target doses and TCP values using inhomogeneous dose distributions could be achieved for all patients, regardless of lymph node involvement, tumour stage, location, and size. These new treatment plans have the potential to increase the local tumour control by 10–15 percentage points without compromising the clinically acceptable lung toxicity level.
FLT1 kinase is a mediator of radioresistance and survival in head and neck squamous cell carcinoma
Creators: name: Porcu, Michaël
name: Cools, Jan
name: Nuyts, Sandra
name: Limbergen, Evert Jan Van
name: Zabrocki, Piotr
name: Hauben, Esther
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biochemistry

description: Head and neck squamous cell carcinoma (HNSCC) is the fifth most common malignancy worldwide, responsible for approximately half a million new cases every year. The treatment of this disease is challenging and characterised by high rates of therapy failure and toxicity, stressing the need for new innovative treatment strategies. Material and methods. In this study we performed a shRNAmir-based screen on HNSCC cells with the aim to identify tyrosine kinases that are mediating radiotherapy resistance. Results. The receptor tyrosine kinase FLT1 (VEGFR1) was identified as an important driver of cell survival and radioresistance. We show that FLT1 is phosphorylated in HNSCC cells, and document autocrine production of FLT1 ligands VEGFA and VEGFB, leading to receptor activation. Immunohistochemistry on HNSCC patient samples demonstrated FLT1 and VEGFA to be uniformly expressed. Interestingly, FLT1 was selectively overexpressed in tumour tissue as compared to non-cancerous epithelium. Remarkably, we found only membrane permeable FLT1 kinase inhibitors to be effective, which was in agreement with the intracellular localisation of FLT1. Discussion and conclusion. Taken together, we document expression of FLT1 in HNSCC and demonstrate this kinase to modulate radioresistance and cancer cell survival. Given the fact that FLT1 kinase is selectively upregulated in tumour tissue and that its kinase function seems expendable for normal life and development, this kinase holds great promise as a new potential therapeutic target.
Cone beam CT verification for active breathing control (ABC)-gated radiotherapy for lung cancer
Creators: name: Ashley, Sue
name: Kheng-Wei Yeoh
name: McNair, Helen A.
name: McDonald, Fiona
name: Hawkins, Maria
name: Hansen, Vibeke N.
name: Ramos, Monica
name: Fragkandrea, Ioanna
name: Bothwell, Sarah
name: Herbert, Trina
name: Taylor, Helen
name: Helyer, Sarah
name: Brada, Michael
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Developmental Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Medicine
subject: Physics

description: Cone beam CT verification for active breathing control (ABC)-gated radiotherapy for lung cancer
Genitourinary anatomy; contains Three Stage Repair for Penoscrotal Hypospadias (Medical illustrations)
Creators: name: Francone, Clarice Ashworth
Publisher: name: Oregon Health & Science University
Year: 0
Subjects: Medical Illustration
Penis
Testis
Scrotum
Genitalia, Male
Anatomy, Cross-Sectional
Urologic Surgical Procedures, Male

description: 24 detailed pencil sketches of the penis, testicles and related internal reproductive organs. Includes cross sections from the side, testicular surgeries and testicular removal.
title: Amo awareba
title: My story
titleType: AlternativeTitle
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Eramiri is telling what she had done earlier that morning and how she helped Moisés come to Bibi Oboro's house
Gynecology; contains Physiology and Disorders of Menstruation in Research In the Service of Medicine (Medical illustrations)
Creators: name: Francone, Clarice Ashworth
Publisher: name: Oregon Health & Science University
Year: 0
Subjects: Medical Illustration
Genitalia, Female
Ovary
Pregnancy
Menstruation
Fallopian Tubes

description: Pencil sketches of the vagina, ovaries, fallopian tubes, the process of menstruation and pregnancy.
Renewable energy development and the Native Title Act 1993 (Cwlth): The fairness of validating future acts associated with renewable energy projects
Creators: name: Maynard, Ganur
Publisher: name: Centre for Aboriginal Economic Policy Research
Year: 2022
Subjects: Native title
renewable energy
free and prior informed consent

description: Increasing demand, innovations in technology, and extensions to electricity grid infrastructure are likely to lead to a growth in renewable energy development on native title land and water. The likelihood that native title holders and claimants will benefit from this development will depend in part upon the legal regime that governs native title. The prevailing legal regime governing renewable energy development on native title land and water involves two principal alternatives to permitting development: voluntary land use agreements and compulsory government acquisition of native title. While the procedures associated with these alternatives afford native title holders and claimants more procedural protection than some commentators have suggested, they fail to attain the standard of ‘free, prior, and informed consent’ prescribed by international best practice and the philosophical and moral arguments that underpin that standard. To remedy this failure, the Native Title Act 1993 (Cwlth) should be amended to place less weight on economic and similar considerations when authorising the compulsory acquisition of native title for renewable energy development, or prohibit the compulsory acquisition of native title generally, except for in certain exceptional circumstances. While this paper focuses on renewable energy in particular, a number of its conclusions could apply to issues that attenuate native title generally.
Risk-adapted strategy partial liver irradiation for the treatment of large volume metastatic liver disease
Creators: name: Nutting, Christopher M.
name: Aitken, Katharine L.
name: Tait, Diana M.
name: Komel Khabra
name: Hawkins, Maria A.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Cancer
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Physiology
subject: FOS: Biological sciences
subject: Medicine
subject: Physics

description: Risk-adapted strategy partial liver irradiation for the treatment of large volume metastatic liver disease
Three Essays on Behavioral Bias in the Financial Market
Creators: name: Chen, Shuang
Publisher: name: The Australian National University
Year: 2022

description: This thesis consists of three chapters. The first chapter is titled Information Dissemination and Behavioral Bias in Financial Media, which examines how behavioral bias affects the information dissemination role of financial media. By utilizing information from Gallup Survey and immigration records, we construct a measure of journalist surname favorability. We find that journalists with more favorable surnames have stronger impact on the stock price. This effect is more pronounced for stocks with smaller firm size, lower institutional ownership, and lower analyst coverage. We further use the U.S.-China trade war as an exogenous shock to the measure of journalist surname favorability and show that news articles released by journalists with Chinese-origin surnames elicit weaker market reactions during the trade war period. Finally, we find that the stock price shows return reversal patterns after controlling for well-known risk factors. The second chapter, Behavioral Bias in Patent Applications, examines whether behavioral bias affects the patent grant outcomes in the U.S. patent system. We demonstrate that inventors with more favorable surnames are more likely to have patent granted. In addition, conditional on successful applications, the examination processing time is shorter for inventors with more favorable surnames, while conditional on unsuccessful applications, the examination processing time is shorter for inventors with unfavorable surnames. Finally, we introduce three events, the 9/11 terrorist attack, the German-French opposition to the Iraq War, and the U.S.-China trade war, as exogenous shocks to inventor surname favorability, and show that the patent grant probability significantly decreases after these events happened. We show evidence that our findings are not driven by the differential quality of underlying inventions. The third chapter, Strategic Disclosure and Behavioral Bias, examines how firms strategically disclose information of foreign countries in the 10-K filings based on investors' perceptions of foreign countries. We find that firms mention foreign countries more when investors show more favorable perceptions of those countries, conditional on firms having subsidiaries in those countries. Moreover, this effect significantly decreases when the exogenous shocks happen. Finally, both firms' idiosyncratic volatility and political risk increase when firms mention more on foreign countries affected by the exogenous shocks.
Efficacy of multispecies probiotics for patients with irritable bowel syndrome
Creators: name: 吕林玲
Publisher: name: CNGB
Year: 2024
Subjects: Metabolome
Monoisolate

description: Background Probiotics and fecal microbiota transplantation (FMT) have shown potential benefits in irritable bowel syndrome (IBS). This study investigates the efficacy of multispecies probiotics on IBS symptoms and associated gut microbiota changes in participants, aiming to clarify their therapeutic potential.
Results We found the responses occurred in 73% and 68% of the patients who received multispecies probiotics and FMT, respectively at 12 weeks. These were accompanied by significant improvements in anxiety, depression, and the quality of life in either group. Also, the improvement in abdominal pain and stool consistency lower score occurred in probiotics group but not in FMT group. Fecal analysis revealed that FMT changed significantly improving the microbiota community structure at 2 weeks, while multispecies probiotics started at 4 weeks and was maintained until 12 weeks.
Conclusions Multispecies probiotics are effective and comparable to FMT in improving the symptoms of IBS. The alterations of gut microbiota in the composition induced and maintained by multispecies probiotics group was better than FMT group.
title: Damo i tere pi istori abada baba pime
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Eramiri is explaining what she did earlier that day: from wakin up, seeing a white man coming down, seeing some girls cooking and then resting for the rest of the day.
Hand (Medical illustrations)
Creators: name: Francone, Clarice Ashworth
Publisher: name: Oregon Health & Science University
Year: 0
Subjects: Medical Illustration
Hand
Equipment and Supplies
General Surgery

description: 79 pencil sketches of hands from various angles and positions, unlabeled. Also includes sketches of hands holding pens, pens, pencils, medical instruments and closeups of hands performing surgery.
Hausrath et al. SOM
Creators: name: Hausrath, Elisabeth
name: Sullivan, Robert
name: Goreva, Yulia
name: Zorzano, Maria-Paz
name: Vaughan, Alicia
name: Cousin, Agnes
name: Siljestrom, Sandra
name: Sharma, Sunanda
name: Shumway, Andrew
name: Kizovski, T.
name: VanBommel, Scott
name: Tice, Michael
name: Knight, Abigail
name: Martínez, Germán
name: Vicente-Retortillo, Alvaro
name: Mandon, Lucia
name: Adcock, Christopher
name: Madariaga, J.
name: Poblacion, Iratxe
name: Johnson, J.
name: Lasue, Jeremie
name: Gasnault, O.
name: Randazzo, Nicolas
name: Cardarelli, Emily
name: Kronyak, Rachel
name: Bechtold, andreas
name: Paar, Gerhard
name: Udry, Arya
name: Forni, Olivier
name: Bedford, Candice
name: Carman, Nancy
name: Bell, James
name: Benison, Kathleen
name: Bosak, T.
name: Brown, A.
name: Broz, Adrian
name: Calef, Fred
name: Clark, Benjamin
name: Cloutis, E.
name: Czaja, Andrew
name: Fornaro, Teresa
name: Fouchet, T.
name: Golombek, Matthew
name: Gomez, Felipe
name: Herd, C.
name: Herkenhoff, Kenneth
name: Jakubek, Ryan
name: Jandura, Louise
name: Martinez-Frias, Jesus
name: Mayhew, Lisa
name: Meslin, Pierre-Yves
name: Newman, Claire
name: Nunez, J.
name: Poulet, Francois
name: Royer, Clement
name: Russell, Patrick
name: Sephton, Mark A.
name: Sharma, Shiv
name: Shuster, David
name: Simon, J.
name: Tirona, Iona
name: Wiens, R.
name: Weiss, Benjamin
name: Williams, Amy
name: Williford, Kenneth
name: Wolf, Z.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 510905
subject: Solar system planetary science (excl. planetary geology)

description: This is the Supporting Information for Hausrath et al. "Collection and in situ analyses of regolith samples by the Mars 2020 rover: Implications for their formation and alteration history"Contents include:Text S1Figures S1 to S7Tables S1 to S8https://www.youtube.com/watch?v=fpc1PxiXMVoAdditional Supporting Information (Files uploaded separately)Table S9. Measured grain sizes from Topographers PeakTable S10. Chemical compositions of undisturbed (crusted soils) on Mars
Table S11. Chemical compositions of disturbed (Fine-grained soils) on Mars
Table S12. Observation Mountain Sampling activitiesTable S13. SuperCam Shot-to-Shot Major Oxide Component dataTable S14. Members of the Regolith Working GroupSupplementary Movie megaripples wind eventCrosswind Lake Pre-post samplingRegolith sample area
title: Ipiri apa kuma pime daru
title: Prayer
titleType: AlternativeTitle
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Kakoro prays the Christian God so that he can give him the knowledge to speak in Kibiri language. He also mentions the Jesus' death on the cross and then finishes by talking about the work session he is having with Moisés
Radiation-induced lung injury after concurrent neoadjuvant chemoradiotherapy for locally advanced breast cancer
Creators: name: Chambers, Ann F.
name: Chow, Tiffany L.
name: Louie, Alexander V.
name: Palma, David A.
name: D’Souza, David P.
name: Perera, Francisco
name: Rodrigues, George B.
name: Warner, Andrew
name: Brackstone, Muriel
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Evolutionary Biology
subject: Biotechnology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Medicine
subject: Physics
subject: Engineering
subject: Biophysics

description: Radiation-induced lung injury after concurrent neoadjuvant chemoradiotherapy for locally advanced breast cancer
title: Umo dara umo marewo pime beira ibo koiro ovatime pime
title: What I will do next week
titleType: AlternativeTitle
Creators: name: Velásquez, Moisés
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Kibiri
subject: prm

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
description: Kakoro says what he will do next week: some works at home, so he is informing Moisés that he will not be available to work with him next week