cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ab-initio Study of Electronic and Lattice Dynamical Properties of monolayer ZnO under Strain
Creators: name: Chaudhuri, Saumen
name: Das, A. K.
name: Das, G. P.
name: Dev, B. N.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: First-principles density functional theory based calculations have been performed to investigate the strain-induced modifications in the electronic and vibrational properties of monolayer (ML) ZnO. Wide range of in-plane tensile and compressive strains along different directions are applied to analyse the modifications in detail. The electronic band gap reduces under both tensile and compressive strains and a direct to indirect band gap transition occurs for high values of biaxial tensile strain. The relatively low rate of decrease of band gap and large required strain for direct to indirect band gap transition compared to other $2$D materials are analysed. Systematic decrease in the frequency of the in-plane and increase in the out-of-plane optical phonon modes with increasing tensile strain are observed. The in-plane acoustic modes show linear dispersion for unstrained as well as strained cases. However, the out-of-plane acoustic mode (ZA), which shows quadratic dispersion in the unstrained condition, turns linear with strain. The dispersion of the ZA mode is analysed using the shell elasticity theory and the possibility of ripple formation with strain is analysed. The strain-induced linearity of the ZA mode indicates the absence of rippling under strain. Finally, the stability limit of ML-ZnO is investigated and found that for $18\%$ biaxial tensile strain the structure shows instability with the emergence of imaginary phonon modes. Furthermore, the potential of ML-ZnO to be a good thermoelectric material is analyzed in an intuitive way based on the calculated electronic and phononic properties. Our results, thus, not only highlight the significance of strain-engineering in tailoring the electronic and vibrational properties but also provide a thorough understanding of the lattice dynamics and mechanical strength of ML-ZnO.
description: 12 pages, 8 figures
Cardiac-specific inactivation of Prdm16 effects cardiac conduction abnormalities and cardiomyopathy-associated phenotypes
Creators: name: Ji-One Kang
name: Nam, Jeong Min
name: Lim, Ji Eum
name: Ha, Tae Woong
name: Bermseok Oh
Publisher: name: figshare
Year: 2019
Subjects: subject: 60603 Animal Physiology - Systems
subject: FOS: Biological sciences

description: Supplemental data
Ku complex interacts with and stimulates the Werner protein
Creators: name: The University of North Carolina at Chapel Hill University Libraries
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Werner syndrome (WS) is the hallmark premature aging disorder in which affected humans appear older than their chronological age. The protein WRNp, defective in WS, has helicase function, DNA-dependent ATPase, and exonuclease activity. Although WRNp functions in nucleic acid metabolism, there is little or no information about the pathways or protein interactions in which it participates. Here we identify Ku70 and Ku86 as proteins that interact with WRNp. Although Ku proteins had no effect on ATPase or helicase activity, they strongly stimulated specific exonuclease activity. These results suggest that WRNp and the Ku complex participate in a common DNA metabolic pathway.
ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis
Creators: name: Chen, J.-G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: To directly address the function of a putative auxin receptor designated ABP1, a reverse genetic approach was taken to identify and characterize ABP1 mutant alleles in Arabidopsis. A homozygous null mutation in ABP1 confers embryo lethality. Null mutant embryos develop normally until the early stages of the globular embryo but are unable to make the transition to a bilaterally symmetrical structure because cells fail to elongate. Cell division was also aberrant both in the suspensor and embryo proper. Antisense suppression of ABP1 in tobacco cells causes slow proliferation and eliminates auxin-induced cell elongation and reduces cell division. The complete lack of auxin-inducible elongation in individual cells confirms the results observed in embryos, indicates a cell autonomous function, and, taken together with biochemical evidence that ABP1 binds auxins, suggests that ABP1 mediates auxin-induced cell elongation and, directly or indirectly, cell division.
Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression
Creators: name: Sullivan, E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Replication-associated histone genes encode the only metazoan mRNAs that lack polyA tails, ending instead in a conserved 26-nt sequence that forms a stem–loop. Most of the regulation of mammalian histone mRNA is posttranscriptional and mediated by this unique 3′ end. Stem–loop–binding protein (SLBP) binds to the histone mRNA 3′ end and is thought to participate in all aspects of histone mRNA metabolism, including cell cycle regulation. To examine SLBP function genetically, we have cloned the gene encoding Drosophila SLBP (dSLBP) by a yeast three-hybrid method and have isolated mutations in dSLBP. dSLBP function is required both zygotically and maternally. Strong dSLBP alleles cause zygotic lethality late in development and result in production of stable histone mRNA that accumulates in nonreplicating cells. These histone mRNAs are cytoplasmic and have polyadenylated 3′ ends like other polymerase II transcripts. Hypomorphic dSLBP alleles support zygotic development but cause female sterility. Eggs from these females contain dramatically reduced levels of histone mRNA, and mutant embryos are not able to complete the syncytial embryonic cycles. This is in part because of a failure of chromosome condensation at mitosis that blocks normal anaphase. These data demonstrate that dSLBP is required in vivo for 3′ end processing of histone pre-mRNA, and that this is an essential function for development. Moreover, dSLBP-dependent processing plays an important role in coupling histone mRNA production with the cell cycle.
Black Hole Binaries in Galactic Nuclei and Gravitational Wave Sources
Creators: name: Hong, Jongsuk
name: Lee, Hyung Mok
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Stellar black hole (BH) binaries are one of the most promising gravitational wave (GW) sources for GW detection by the ground-based detectors. Nuclear star clusters (NCs) located at the centre of galaxies are known to harbour massive black holes (MBHs) and to be bounded by a gravitational potential by other galactic components such as the galactic bulge. Such an environment of NCs provides a favourable conditions for the BH-BH binary formation by the gravitational radiation capture due to the high BH number density and velocity dispersion. We carried out detailed numerical study of the formation of BH binaries in the NCs using a series of N-body simulations for equal-mass cases. There is no mass segregation introduced. We have derived scaling relations of the binary formation rate with the velocity dispersion of the stellar system beyond the radius of influence and made estimates of the rate of formation of black hole binaries per unit comoving volume and thus expected detection rate by integrating the binary formation rate over galaxy population within the detection distance of the advanced detectors. We find that the overall formation rates for BH-BH binaries per NC is 10^(-10)/yr for the Milky-Way-like galaxies and weakly dependent on the mass of MBH as M^(3/28). We estimate the detection rate of 0.02-14/yr for advanced LIGO/Virgo considering several factors such as the dynamical evolution of NCs, the variance of the number density of stars and the mass range of MBH giving uncertainties.
description: 17 pages, 19 figures, 2 tables, published in MNRAS
The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes
Creators: name: Tenenhaus, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2001

description: Histone deacetylation plays an important role in methylated DNA silencing. Recent studies indicated that the methyl-CpG-binding protein, MBD2, is a component of the MeCP1 histone deacetylase complex. Interestingly, MBD2 is able to recruit the nucleosome remodeling and histone deacetylase, NuRD, to methylated DNA in vitro. To understand the relationship between the MeCP1 complex and the NuRD complex, we purified the MeCP1 complex to homogeneity and found that it contains 10 major polypeptides including MBD2 and all of the known NuRD components. Functional analysis of the purified MeCP1 complex revealed that it preferentially binds, remodels, and deacetylates methylated nucleosomes. Thus, our study defines the MeCP1 complex, and provides biochemical evidence linking nucleosome remodeling and histone deacetylation to methylated gene silencing.
Field-Emission Resonances in Thin Metallic Films: Nonexponential Decay of the Tunneling Current as a Function of the Sample-to-Tip Distance
Creators: name: Aladyshkin, A. Yu.
name: Schouteden, K.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Field-emission resonances (FERs) for two-dimensional Pb(111) islands grown on \mbox{Si(111)7$\times$7} surfaces were studied by low-temperature scanning tunneling microscopy and spectroscopy (STM/STS) in a broad range of tunneling conditions with both active and disabled feedback loop. These FERs exist at quantized sample-to-tip distances $Z^{\,}_n$ above the sample surface, where $n$ is the serial number of the FER state. By recording the trajectory of the STM tip during ramping of the bias voltage $U$ (while keeping the tunneling current $I$ fixed), we obtain the set of the $Z^{\,}_n$ values corresponding to local maxima in the derived $dZ/dU(U)$ spectra. This way, the continuous evolution of $Z^{\,}_n$ as a function of $U$ for all FERs was investigated by STS experiments with active feedback loop for different $I$. Complementing these measurements by current-distance spectroscopy at a fixed $U$, we could construct a 4-dimensional $I-U-Z-dZ/dU$ diagram, that allows us to investigate the geometric localization of the FERs above the surface. We demonstrate that (i) the difference $δZ^{\,}_n=Z^{\,}_{n+1}-Z^{\,}_n$ between neighboring FER lines in the $Z-U$ diagram is independent of $n$ for higher resonances, (ii) the $δZ^{\,}_{n}$ value decreases as $U$ increases; (iii) the quantized FER states lead to the \emph{periodic} variations of $\ln I$ as a function of $Z$ with periodicity $δZ$; (iv) the periodic variations in the $\ln I - Z$ spectra allows to estimate the absolute height of the tip above the sample surface. Our findings contribute to a deeper understanding on how the FER states affect various types of tunneling spectroscopy experiments and how they lead to a non-exponential decay of the tunneling current as a function of $Z$ at high bias voltages in the regime of quantized electron emission.
description: 25 pages, 18 figures
D8.14 Report on the Contribution to Standardisation
Creators: name: Suo, Amanda
Publisher: name: Zenodo
Year: 2022

description: UNE, member of the SHAREWORK project, is in charge of the T8.3 “Standardisation activities” and has prepared the deliverable D8.14 “Report on the Contribution to Standardisation” showing the results of the relations with Standardisation in the project. Standardisation has been used as a valuable input for the project, considering the current documents as the state of the art of the industry in the fields of Human-Robot Collaboration, Robotics and AI. The Standardisation environment has also been used for dissemination of the results of the project within the industry and public administration, via Technical Committees (TC). Standardisation documents are commonly used in public and private community as the reference for industrial practices in Europe. Thus, including the results of ‘SHAREWORK’ in a CEN document was considered as a high success that should be pursued. The main goal in task T8.3.2 was the drafting (and if possible the publication) of a CEN Workshop Agreement (CWA). After the assessment of the Standardisation environment made in M30, UNE presented to CEN a CEN WS Proposal and Project Plan for the activation of a project based on the “advanced Human-Robot Collaborative cells design methodology” established in personalized HRC systems of ‘SHAREWORK’. The activation was accepted and the Kick-off meeting (first WS meeting) took place virtually in October 2022. The successful result of this group is the development of the CEN document CWA 'Guidelines for design of advanced Human–Robot Collaborative cells in personalized HRC systems'. The European Standardisation system is one of the most relevant tools for “peer-review” of the innovation initiatives, as industry and public bodies from European 33 countries receive the information and can react, comment and participate. The main dissemination result of this project is the CWA document, but the dissemination of the project through the Standardisation system, in physical meetings or using the digital tools of CEN, are also a very interesting source of visibility for ‘SHAREWORK’.
A one-dimensional Chandrasekhar-mass delayed-detonation model for the broad-lined Type Ia supernova 2002bo
Creators: name: Blondin, Stéphane
name: Dessart, Luc
name: Hillier, D. John
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present 1D non-local thermodynamic equilibrium (non-LTE) time-dependent radiative-transfer simulations of a Chandrasekhar-mass delayed-detonation model which synthesizes 0.51 Msun of 56Ni, and confront our results to the Type Ia supernova (SN Ia) 2002bo over the first 100 days of its evolution. Assuming only homologous expansion, this same model reproduces the bolometric and multi-band light curves, the secondary near-infrared (NIR) maxima, and the optical and NIR spectra. The chemical stratification of our model qualitatively agrees with previous inferences by Stehle et al., but reveals significant quantitative differences for both iron-group and intermediate-mass elements. We show that +/-0.1 Msun (i.e., +/-20 per cent) variations in 56Ni mass have a modest impact on the bolometric and colour evolution of our model. One notable exception is the U-band, where a larger abundance of iron-group elements results in less opaque ejecta through ionization effects, our model with more 56Ni displaying a higher near-UV flux level. In the NIR range, such variations in 56Ni mass affect the timing of the secondary maxima but not their magnitude, in agreement with observational results. Moreover, the variation in the I, J, and K_s magnitudes is less than 0.1 mag within ~10 days from bolometric maximum, confirming the potential of NIR photometry of SNe Ia for cosmology. Overall, the delayed-detonation mechanism in single Chandrasekhar-mass white dwarf progenitors seems well suited for SN 2002bo and similar SNe Ia displaying a broad Si II 6355 A line. Whatever multidimensional processes are at play during the explosion leading to these events, they must conspire to produce an ejecta comparable to our spherically-symmetric model.
description: Accepted for publication in MNRAS. The hydrodynamical input and synthetic spectra are available at https://www-n.oca.eu/supernova/home.html . Minor changes from v1: corrected several typos and updated acknowledgements
Using microworlds for policymaking in the context of resilient farming systems
Creators: name: Herrera, Hugo
name: Kopainsky, Birgit
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy

description: Resilience management of farming systems requires building an understanding of the underlying drivers of the adaptive capacity of the system. In this paper, we use the concept of resilience as a framework to understand how bovine livestock farming systems may adjust to challenging environmental, social, and political conditions. Using an interactive simulation model (microworld), we explored potential developments for livestock farmers in Bourbonnais, France, to the effect of simultaneous changes in the socioeconomic landscape and unpredictable weather conditions resulting from climate change. The results offer insights into the potential trade-offs between systems scale and long-term sustainability by suggesting that sacrificing socioeconomic performance in the short and medium term may increase long-term sustainability and resilience.
A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing
Creators: name: Dominski, Z.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The stem–loop binding protein (SLBP) is the posttranscriptional regulator of histone mRNA in metazoan cells. SLBP binds histone pre-mRNAs and facilitates 3′-end processing by promoting stable association of U7 snRNP with the pre-mRNA. To identify other factors involved in histone pre-mRNA processing, we used a modified yeast two-hybrid assay in which SLBP and its RNA target were coexpressed as bait. A novel zinc finger protein, hZFP100, which interacts with the SLBP/RNA complex but not with free SLBP, was cloned. The interaction requires regions of SLBP that are important for histone pre-mRNA processing. Antibodies to hZFP100 precipitate U7 snRNA, and expression of hZFP100 in Xenopus oocytes stimulates processing of histone pre-mRNA, showing that hZFP100 is a component of the processing machinery.
Cooperative Positioning for Sparsely Distributed High-Mobility Wireless Networks with EKF Based Spatio-Temporal Data Fusion
Creators: name: Cao, Yue
name: Yang, Shaoshi
name: Ma, Xiao
name: Feng, Zhiyong
Publisher: name: arXiv
Year: 2023
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: We propose a distributed cooperative positioning algorithm using the extended Kalman filter (EKF) based spatio-temporal data fusion (STDF) for a wireless network composed of sparsely distributed high-mobility nodes. Our algorithm first makes a coarse estimation of the position and mobility state of the nodes by using the prediction step of EKF. Then it utilizes the coarse estimate as the prior of STDF that relies on factor graph (FG), thus facilitates inferring a posteriori distributions of the agents' positions in a distributed manner. We approximate the nonlinear terms of the messages passed on the associated FG with high precision by exploiting the second-order Taylor polynomial and obtain closed-form representations of each message in the data fusion step, where temporal measurements by imperfect hardware are considered additionally. In the third stage, refinement of position estimate is performed by invoking the update step of EKF. Simulation results and analysis show that our EKF-STDF has a lower computational complexity than the state-of-the-art EKF-based algorithms, while achieving an even superior positioning performance in harsh environment.
description: 5 pages, 3 figures, accepted to appear on IEEE Communications Letters, Jun. 2023
Lifting to the spectral ball with interpolation
Creators: name: Andrist, Rafael B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Complex Variables (math.CV)
subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 30E05 (primary), 32Q55, 32M10 (secondary)

description: We give necessary and sufficient conditions for solving the spectral Nevanlinna--Pick lifting problem. This reduces the spectral Nevanlinna--Pick problem to a jet interpolation problem into the symmetrized polydisc.
description: 7 pages; corrections to references and typos
D8.12 Final Public Communication Materials
Creators: name: Presas, Marina
Publisher: name: Zenodo
Year: 2021

description: As the project coordinator of Sharework project Simona Neri informed the Project Officer the past December 1st 2021 via email, the submission date of Deliverable 8.12, to be submitted according to the project plan by the end of December 2021, is not correct. This deliverable was planned to be submitted by the end of the project on M48, in line with D8.13 – Final PUDR and compile all new communication materials produced from M36 to M48. Recent communication materials and activities carried out were reported on October 2021 in D8.8 – Public Communication Materials. In addition, updates on this activity were included in the technical review report and review meeting presentation during November 2021. To our understanding, replicating the previous deliverable without new content is counter-productive, whilst this deliverable can provide valuable input to the European Commission if produced by the end of the project. Therefore, we believe it is better to postpone the production of this deliverable by M48, when we compromise to submit it in a timely manner and with updates on communication activities.
Distinct requirements for Ras oncogenesis in human versus mouse cells
Creators: name: Hamad, N. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The spectrum of tumors associated with oncogenic Ras in humans often differs from those in mice either treated with carcinogens or engineered to sporadically express oncogenic Ras, suggesting that the mechanism of Ras transformation may be different in humans. Ras stimulates primarily three main classes of effector proteins, Rafs, PI3-kinase, and RalGEFs, with Raf generally being the most potent at transforming murine cells. Using oncogenic Ras mutants that activate single effectors as well as constitutively active effectors, we find that the RalGEF, and not the Raf or PI3-kinase pathway, is sufficient for Ras transformation in human cells. Thus, oncogenic Ras may transform murine and human cells by distinct mechanisms, and the RalGEF pathway—previously deemed to play a secondary role in Ras transformation—could represent a new target for anti-cancer therapy.
Effect of Post-Process Heat Treatment on the Microstructure and Tensile Behaviour of Wire Arc Additive Manufactured 13-8 PH Martensitic Stainless Steel
Creators: Ghaffari, Mahya
Nemani, Alireza Vahedi
Nasiri, Ali
Publisher: name: University of Alberta Library
Year: 2022

Conference Abstract. Part of the Proceedings of the Canadian Society for Mechanical Engineering International Congress 2022.
Are “wrong” models useful? A qualitative study of discrete event simulation modeller stories
Creators: name: Tsioptsias, Naoum
name: Tako, Antulea A.
name: Robinson, Stewart
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Little is known about models deemed ”wrong” by their modellers or clients in Operational Research (OR). This paper aims to improve our understanding of “wrong” Discrete Event Simulation (DES) models based on empirical evidence. We interview 22 modellers who describe projects where modelling did not go as expected and explain how they dealt with those situations. This resulted in 54 stories reporting that a model was identified ”wrong” either by the modeller, the client or both. We perform a qualitative text analysis of the stories to identify the factors that define a ”wrong” model as well as potential uses of ”wrong” models. The results show that some models even though considered ”wrong” may still be useful in practice and provide valuable insights to users and modellers. This study offers practical suggestions for users and modellers to consider when dealing with a model that is considered ”wrong”.
Models of care for pregnant women and birthing people with Multiple Long-Term Conditions and the role of the midwife: a scoping review protocol
Creators: name: Vowles, Zoe
name: Black, Mairead
name: Lovell, Holly
name: Sandall, Jane
name: Easter, Abigail
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Nursing Midwifery
subject: Nursing
subject: FOS: Health sciences
subject: Obstetrics and Gynecology
subject: Medicine and Health Sciences
subject: Medical Specialties

description: This protocol describes a strategy to identify and summarise the different types of evidence on models of care for pregnant, birthing, and postnatal women and birthing people with Multiple Long-Term Conditions, and the role of the midwife in different models of care provision. This will be used to identify research gaps to make recommendations for the future research.
Thermodynamical First Laws of Black Holes in Quadratically-Extended Gravities
Creators: name: Fan, Zhong-Ying
name: Lu, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Einstein gravities in general dimensions coupled to a cosmological constant and extended with quadratic curvature invariants admit a variety of black holes that may asymptote to Minkowski, anti-de Sitter or Lifshitz spacetimes. We adopt the Wald formalism to derive an explicit formula for calculating the thermodynamical first law for the static black holes with spherical/toric/hyperbolic isometries in these theories. This allows us to derive/rederive the first laws for a wide range of black holes in literature. Furthermore, we construct many new exact solutions and obtain their first laws.
description: Latex, 29 pages, many typos (spotted by the referee of PRD) corrected, to appear in PRD
LITHUANIA - Migration and demographic patterns in Central-Eastern Europe
Creators: name: Brzozowski, Jan
name: Wojno, Przemysław
name: Ćwiklicki, Marek
name: Chwat, Olivia
Publisher: name: Zenodo
Year: 2023
Subjects: lithuania
migration
migration scenarios

description: This report is a part of deliverable “D.6.2. Report on migration and demographic patterns in the EU CEE countries and potential source countries” from the project FUME – Future Migration Scenarios for Europe (870649), financed with the Horizon 2020 programme. In particular, this country report focuses on critical analysis of immigration data from Lithuania. The analysis consists of an overview of stock and flow data on migrants including such dimensions as: age groups, gender, country of origin, education levels, and length of residence. This report is a first step in an analytical exercise, which aims to determine migration potential from and to Lithuania and furthermore, to provide necessary data input for fine-tuning of the FUME migration projection model. The report presents the historical framework of the migration transition of Lithuania from migrant-sending to migrant-receiving country, major national groups of immigrants and their demographic structure. It also provides critical analysis on the validity of various statistical sources of data and draws some initial conclusions on the temporality/permanent nature of immigration in Lithuania. Lithuania, as other Baltic states included in this deliverable, shares some similar patterns of migration due to a common history, including Russian and Soviet political dominance, political oppression during the communist times, and settlement policies within the USRR. Yet, Lithuania presents also some different patterns from Estonia and Latvia. This includes, inter alia, the longer history and richer traditions of independence, which have an influence on more inclusive policies on immigration and citizenship than the other two Baltic republics.
Evidence of coupling between the thermal and nonthermal emission in the gamma-ray binary LS I +61 303
Creators: name: Paredes-Fortuny, X.
name: Ribó, M.
name: Bosch-Ramon, V.
name: Casares, J.
name: Fors, O.
name: Núñez, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The gamma-ray binary LS I +61 303 is composed of a Be star and a compact companion orbiting in an eccentric orbit. Variable flux modulated with the orbital period of ~26.5 d has been detected from radio to very high-energy gamma rays. In addition, the system presents a superorbital variability of the phase and amplitude of the radio outburst with a period of ~4.6 yr. We present optical photometric observations of LS I +61 303 spanning ~1.5 yr and contemporaneous Halpha equivalent width (EW Halpha) data. The optical photometry shows, for the first time, that the known orbital modulation suffers a positive orbital phase shift and an increase in flux for data obtained 1-yr apart. This behavior is similar to that already known at radio wavelengths, indicating that the optical flux follows the superorbital variability as well. The orbital modulation of the EW Halpha presents the already known superorbital flux variability but shows, also for the first time, a positive orbital phase shift. In addition, the optical photometry exhibits a lag of ~0.1-0.2 in orbital phase with respect to the EW Halpha measurements at similar superorbital phases, and presents a lag of ~0.1 and ~0.3 orbital phases with respect noncontemperaneous radio and X-ray outbursts, respectively. The phase shifts detected in the orbital modulation of thermal indicators, such as the optical flux and the EW Halpha, are in line with the observed behavior for nonthermal indicators, such as X-ray or radio emission. This shows that there is a strong coupling between the thermal and nonthermal emission processes in the gamma-ray binary LS I +61 303. The orbital phase lag between the optical flux and the EW Halpha is naturally explained considering different emitting regions in the circumstellar disk, whereas the secular evolution might be caused by the presence of a moving one-armed spiral density wave in the disk.
description: 4 pages, 3 figures, accepted for publication in A&A (this version matches the published version)
Effects of 100% organic feeding on performance, carcass composition and fat quality of fattening pigs
Creators: name: Quander-Stoll, Nele
name: Bautze, David
name: Zollitsch, Werner
name: Leiber, Florian
name: Früh, Barbara
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: In organic pig production, one important aim is to achieve 100% organic feeding. This generates the challenge of achieving adequate protein quality in pig feed. Until 31st December 2021, the protein quality in organic pig feed in Europe was improved by using 5% conventional components, mainly potato protein. To investigate the effects of 100% organic feeding on growth performance, meat and fat quality in pigs, a total of 700 fattening pigs were studied in an on-farm feeding trial. The 95% organic diet fed on each farm served as the control diet (CON) and a 100% organic diet with higher proportions of soybean cake and grain legumes was used as the experimental diet (ORG). ORG-fed animals had slightly lower daily weight gains, lower carcass weight, and significantly higher iodine and PUFA values in the backfat. The feeding trial showed that the 100% organic diet led to a slightly deficient dietary amino acid profile and thus to slightly lower performance in a few traits. However, the implementation of consistent 100% organic feeding was considered valuable for organic farming even with the lower performance and change in meat and fat quality of the organic pigs.
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association
Creators: name: Ng, H. H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The amino-terminal histone tails are subject to covalent post-translational modifications such as acetylation, methylation, and phosphorylation. In the histone code hypothesis, these exposed and unstructured histone tails are accessible to a repertoire of regulatory factors that specifically recognize the various modified histones, thereby generating altered chromatin structures that mediate specific biological responses. Here, we report that lysine (Lys) 79 of histone H3, which resides in the globular domain, is methylated in eukaryotic organisms. In the yeast Saccharomyces cerevisiae, Lys 79 of histone H3 is methylated by Dot1, a protein shown previously to play a role in telomeric silencing. Mutations of Lys 79 of histone H3 and mutations that abolish the catalytic activity of Dot1 impair telomeric silencing, suggesting that Dot1 mediates telomeric silencing largely through methylation of Lys 79. This defect in telomeric silencing might reflect an interaction between Sir proteins and Lys 79, because dot1 and Lys 79 mutations weaken the interaction of Sir2 and Sir3 with the telomeric region in vivo. Our results indicate that histone modifications in the core globular domain have important biological functions.
Exousia and Conflict in the Gospel of Mark
Creators: name: König, Judith
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: Gospel of Mark; conflict; literary strategies; authority of Jesus
subject: 230 Theologie, Christentum

description: Interest in the Gospel of Mark has been steadily growing in the field of biblical studies for years. Although Mark’s narrative had long been treated as less polished and thus theologically lacking compared to the other canonical gospels in the past, many scholars now recognize it as a complex narrative with various intertwining and intentionally employed plots and storylines. This study aims to contribute to this growing scholarship which takes the narrative skill of Mark’s author seriously when it traces the term ἐξουσία (exousia) throughout the whole gospel. Special attention will be paid to the way ἐξουσία (exousia) is connected to conflict. Read through this lens, several interesting developments in the Markan presentation of Jesus, the disciples, and reader involvement will emerge. Finally, the question of why ἐξουσία (exousia) is totally absent from the Markan passion story will be answered. This study proposes to see Jesus’ suffering and death on the cross as a consequence of his practice of ἐξουσία (exousia) for which readers are prepared from the beginning of Mark’s narrative.
A simple network-based probabilistic method for estimating recovery of lifeline services to buildings after an earthquake
Creators: name: Mohammadgholibeyki, Negar
name: Koliou, Maria
name: Liel, Abbie B.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: The assessment of how to regain pre-event functionality of buildings after an earthquake within an adequate time has gained attention in the last years, where a critical aspect is to identify the restoration time of the lifeline services that serve those buildings. Existing studies focused on developing frameworks for specific topologies and hazard levels. These methods are mostly out of reach for practicing engineers because of the necessity of identifying the network topology, performing complex network analysis, or conducting a regional seismic hazard analysis. This study develops a generic, network-based probabilistic method to estimate the restoration time of interdependent lifeline services to buildings after an earthquake. By avoiding the complexities above, this method links lifeline networks to utility service restoration to generate service restoration curves useful for building functional recovery assessments. An application to Shelby County and Napa is presented, showing reasonable agreement with more complex network-based analyses. Due to limitations in estimating component quantities and fragility information in regions without data, as well as other assumptions, differences are observed while comparing this method to more rigorous approaches. Still, those differences are acceptable considering the scope of this work for supporting building decision analyses.
title: A short note on coproducts of Abelian pro-Lie groups
Creators: name: Herfort, Wolfgang
name: Hofmann, Karl H.
name: Russo, Francesco G.
Publisher: name: Springer
Year: 2025

description: The notion of conditional coproduct of a family of abelian pro-Lie groups in the category of abelian pro-Lie groups is introduced. It is shown that the cartesian product of an arbitrary family of abelian pro-Lie groups can be characterized by the universal property of the conditional coproduct.
Sensing of intermediates in V(D)J recombination by ATM
Creators: name: Perkins, E. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Ataxia-telangiectasia mutated (ATM) is required for resistance to radiation-induced DNA breaks. Here we use chromatin immunoprecipitation to show that ATM also localizes to breaks associated with V(D)J recombination. ATM recruitment to the recombining locus correlates approximately with recruitment of the break-initiating factor RAG1 and precedes efficient break repair, consistent with localization of ATM to normal recombination intermediates. A product of ATM kinase activity, Ser 18-phosphorylated p53, was detected similarly at these breaks, arguing that ATM phosphorylates target proteins in situ. We suggest routine surveillance of intermediates in V(D)J recombination by ATM helps suppress potentially oncogenic translocations when repair fails.
The hypercentral Constituent Quark Model and its application to baryon properties
Creators: name: Giannini, M. M.
name: Santopinto, E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The hypercentral Constituent Quark Model (hCQM) for the baryon structure is reviewed and its applications are systematically discussed. The model is based on a simple form of the quark potential, which contains a Coulomb-like interaction and a confinement, both expressed in terms of a collective space coordinate, the hyperradius. The model has only three free parameters, determined in order to describe the baryon spectrum. Once the parameters have been fixed, the model, in its non relativistic version, is used to predict various quantities of physical interest, namely the elastic nucleon form factors, the photocouplings and the helicity amplitudes for the electromagnetic excitation of the baryon resonances. In particular, the $Q^2$ dependence of the helicity amplitude is quite well reproduced, thanks to the Coulomb-like interaction. The model is reformulated in a relativistic version by means of the Point Form hamilton dynamics. While the inclusion of relativity does not alter the results for the helicity amplitudes, a good description of the nucleon elastic form factors is obtained.
description: To appear in Chinese Journal of Physics
D8.6 Public Communication Materials I
Creators: name: Presas, Marina
Publisher: name: Zenodo
Year: 2020

description: This deliverable details the communications activities done during M1-M18 including, among others, the development of a corporate visual identity manual, print and digital dissemination and promotional materials designed, social media activity and press releases written. It is worth noting that in order to protect the commercial interests of the industrial participants, publication of the materials has been selective.
Complexity evaluation of network configurations and abstractions
Creators: name: Moreno, Jose
Publisher: name: arXiv
Year: 2023
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Computer networks have been traditionally configured by humans using command-line interfaces. Some network abstractions have emerged in the last 10 years, but there is no easy way of comparing them to each other objectively. Therefore, there is no consensus in the industry of what direction modern network abstractions should take, and the adoption of these abstractions lags as a consequence. In this paper I propose a comparison framework using metrics derived from graph structures to evaluate the simplicity, efficiency, and effectiveness of different network abstraction models. The result of this comparison is that while some of the existing network abstractions are quite efficient to store network policy (such as the Kubernetes or the Cisco Application Centric Infrastructure models), others (notably public cloud) are still very infrastructure-centric and suffer from excessive complexity.
description: 19 pages
Genetics of dark skin in mice
Creators: name: Fitch, K. R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Chemical mutagenesis in the mouse is a powerful approach for phenotype-driven genetics, but questions remain about the efficiency with which new mutations ascertained by their phenotype can be localized and identified, and that knowledge applied to a specific biological problem. During a global screen for dominant phenotypes in about 30,000 animals, a novel class of pigmentation mutants were identified by dark skin (Dsk). We determined the genetic map location, homozygous phenotype, and histology of 10 new Dsk and 2 new dark coat (Dcc) mutations, and identified mutations in Agouti (Met1Leu, Dcc4), Sox18 (Leu220ter, Dcc1), Keratin 2e (Thr500Pro, Dsk2), and Egfr (Leu863Gln, Dsk5). Cutaneous effects of most Dsk mutations are limited to melanocytes, except for the Keratin 2e and Egfr mutations, in which hyperkeratosis and epidermal thickening precede epidermal melanocytosis by 3–6 wk. The Dsk2 mutation is likely to impair intermediate filament assembly, leading to cytolysis of suprabasal keratinocytes and secondary hyperkeratosis and melanocytosis. The Dsk5 mutation causes increased tyrosine kinase activity and a decrease in steady-state receptor levels in vivo. The Dsk mutations represent genes or map locations not implicated previously in pigmentation, and delineate a developmental pathway in which mutations can be classified on the basis of body region, microscopic site, and timing of pigment accumulation.
The Compton hump and variable blue wing in the extreme low-flux NuSTAR observations of 1H0707-495
Creators: name: Kara, E.
name: Fabian, A. C.
name: Lohfink, A. M.
name: Parker, M. L.
name: Walton, D. J.
name: Boggs, S. E.
name: Christensen, F. E.
name: Hailey, C. J.
name: Harrison, F. A.
name: Matt, G.
name: Reynolds, C. S.
name: Stern, D.
name: Zhang, W. W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The Narrow-line Seyfert I galaxy, 1H0707-495, has been well observed in the 0.3-10 keV band, revealing a dramatic drop in flux in the iron K alpha band, a strong soft excess, and short timescale reverberation lags associated with these spectral features. In this paper, we present the first results of a deep 250 ks NuSTAR observation of 1H0707-495, which includes the first sensitive observations above 10 keV. Even though the NuSTAR observations caught the source in an extreme low-flux state, the Compton hump is still significantly detected. NuSTAR, with its high effective area above 7 keV, clearly detects the drop in flux in the iron K alpha band, and by comparing these observations with archival XMM-Newton observations, we find that the energy of this drop increases with increasing flux. We discuss possible explanations for this, the most likely of which is that the drop in flux is the blue wing of the relativistically broadened iron K alpha emission line. When the flux is low, the coronal source height is low, thus enhancing the most gravitationally redshifted emission.
description: Submitted to MNRAS, comments are welcome. 9 pages, 5 figures
Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast
Creators: name: Xiao, T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Histone methylation is now realized to be a pivotal regulator of gene transcription. Although recent studies have shed light on a trans-histone regulatory pathway that controls H3 Lys 4 and H3 Lys 79 methylation in Saccharomyces cerevisiae, the regulatory pathway that affects Set2-mediated H3 Lys 36 methylation is unknown. To determine the functions of Set2, and identify factors that regulate its site of methylation, we genomically tagged Set2 and identified its associated proteins. Here, we show that Set2 is associated with Rbp1 and Rbp2, the two largest subunits of RNA polymerase II (RNA pol II). Moreover, we find that this association is specific for the interaction of Set2 with the hyperphosphorylated form of RNA pol II. We further show that deletion of the RNA pol II C-terminal domain (CTD) kinase Ctk1, or partial deletion of the CTD, results in a selective abolishment of H3 Lys 36 methylation, implying a pathway of Set2 recruitment to chromatin and a role for H3 Lys 36 methylation in transcription elongation. In support, chromatin immunoprecipitation assays demonstrate the presence of Set2 methylation in the coding regions, as well as promoters, of genes regulated by Ctk1 or Set2. These data document a new link between histone methylation and the transcription apparatus and uncover a regulatory pathway that is selective for H3 Lys 36 methylation.
title: Gender Equality and Algorithms: HRC Resolution on New and Emerging Technologies
Creators: name: Lütz, Fabian
Publisher: name: DuEPublico
Year: 2023

description: Algorithms increasingly make decisions for humans or support human decision-making (Sunstein 2023). To address cases of discrimination regulatory efforts for Artificial Intelligence (AI) have recently flourished. On 14 July 2023, the UN Human Rights Council adopted Resolution A/HRC/RES/53/29 on New and Emerging Technologies at the 53rd session calling for equal rights offline and online, also regarding gender equality and non-discrimination. It builds on a wide range of texts including the Guiding Principles on Business and Human Rights (UNGPs), the UNESCO Recommendation on the Ethics of AI, which includes a dedicated gender chapter, the Call to Action for Human Rights, the Roadmap for Digital Cooperation, the creation of the Office of the Secretary-General’s Envoy on Technology and the ongoing process of the UN Global Digital Compact.

The present contribution assesses the Resolution through the lens of gender equality, focusing on its added value regarding regulatory efforts for AI by sketching out elements where AI poses opportunities but also risks for gender equality.
description: blog interdisziplinäre geschlechterforschun