cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Change management for services redesign in healthcare: a conceptual framework
Creators: name: Silvola, Sofia
name: Restelli, Umberto
name: Croce, Davide
name: Basu, Debashis
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2024
Subjects: change management
services redesign
conceptual framework
healthcare services
health care organization and management

description: Introduction


The introduction of process innovations in healthcare organizations faces challenges in knowledge sharing and incorporating best practices due to a strong professional autonomy, leading to resistance to change. The healthcare paradigm is shifting towards value-based organizations with a patient-centered approach, requiring multidisciplinary care. Change management is crucial, but current approaches are often limited. This study proposes a conceptual framework to support change management in healthcare services redesign.


Methods


The proposed conceptual framework was developed applying Jabareen's multidimensional and multi-method approach. The methodology involved 8 steps consisting in literature review, thematic and content analyses, concepts deconstruction and aggregation, graphical design of the framework, external validation and revision.


Results


The framework integrates 53 evidences from the literature, 3 macro areas of interest and 42 change management models applied to the healthcare context, through 244 implementation actions. Aggregation of concepts led to 15 macro topics applicable to all levels of change and composing the proposed framework. Interviews validated the framework, emphasizing the importance of people-focused approaches and addressing resistance to change. Moreover, steps most and less cited in the literature are highlighted and differences between developed countries and economies in transition or developing countries are explored.


Conclusions


The article proposes a 15-step framework for change in healthcare services redesign. It integrates evidence from literature and change management models, emphasizing stakeholder involvement. A case study in South Africa highlights the importance of awareness, planning, communication, training, and continuous review. Further validation and adaptation are recommended.
description: Journal of Preventive Medicine and Hygiene, Vol. 65 No. 3 (2024)
Looking for olive XF-resistance under high natural selective pressure in Salento
Creators: name: La Notte Pierfederico,
name: Vincenzo, Roseti
name: Francesco, Specchia
name: Donato, Boscia
name: Sebastiano, Vanadia
name: Giovanni, Mita
name: Giovanni, Melcarne
Publisher: name: Zenodo
Year: 2021
Subjects: subject: plant health
subject: xylella
subject: olive
subject: resistance
subject: http://id.agrisemantics.org/gacs/C20262
subject: http://id.agrisemantics.org/gacs/C270

description: Several success stories in plant pathology indicate that the use of plant genetic resistance is the most effective, durable and environmentally/economically sustainable protection system for the coexistence with harmful organism whenever curative methods lack. In the epidemic of Xylella fastidiosa ST53 in Salento, the cultivars Leccino and FS17 showed interesting resistant traits. This important finding, even if allowed the replanting of olives in infected areas, is considered a starting point being highly desirable to find a wider range of varieties to avoid a dangerous genetic uniformity and to offer alternatives to the growers and oil producers. For this purpose in Salento, a large-scale program for testing the susceptibility of Italian and Mediterranean olive germplasm started and the first long-lasting breeding activities for the resistance/tolerance were initiated. Due to the urgency, the selection of productive plants derived from uncontrolled pollination and seed dissemination was identified as a third approach aimed to save the time of long olive juvenile period and enlarge the genetic variability to be explored looking for resistance or tolerance directly under high selective pressure of inoculum in the infected area. Furthermore, each seedling plant, derived mainly from parentals of the local cultivars, is potentially a new candidate “autochthonous” variety. After 3-years of activity in the framework of the regional project ResiXO and thousands of plants observed/tested, the activities of morphological/technological characterization, as well the pathogenicity tests by pathogen inoculation in controlled conditions started on a panel of candidate potentially resistant genotypes. Positive feedbacks are also coming from a newborn initiative called Xylor (Xylella Olive Resistance), contrived as a citizen science approach launched in September 2019 to involve the local community in the exploration of a huge territory to find plants asymptomatic or with mild symptoms in the abandoned and dying olive orchards.
description: IT; PDF; pierfederico.lanotte@ipsp.cnr.it
Improving the ONE HEALTH approach: a lesson from SARS-CoV-2 pandemic
Creators: name: Marchi, Serena
name: Guarducci, Giovanni
name: Marotta, Maria Giovanna
name: Peccetti, Benedetta
name: Viviani, Simonetta
name: Messina, Gabriele
name: Montomoli, Emanuele
name: Martella, Vito
name: Camero, Michele
name: Trombetta, Claudia Maria
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2024
Subjects: SARS-CoV-2
ONE HEALTH
Surveillance
Zoonosis
Humans and animals
Emergency preparedness
One Health Approach

description: The emergence of SARS-CoV-2 has underscored the critical need to enhance the ONE HEALTH approach which recognizes the interconnectedness of human, animal, and environmental health. In this review we report on various animal species that were infected by SARS-CoV-2 virus during the pandemic with the aim to contribute to the One Health approach. The SARS-CoV-2 pandemic has highlighted the devastating consequences of zoonotic diseases such as COVID19 and has reiterated the critical role that the health of wildlife, domestic animals, and the environment plays in human health. The pandemic is a lesson learnt on the urgent need for an enhanced ONE HEALTH approach by developing a robust and interconnected global health strategy to effectively prevent and control zoonotic diseases and protect the health of all species on our planet. These efforts are crucial for a sustainable and resilient future for both human and ecological systems.
description: Journal of Preventive Medicine and Hygiene, Vol. 65 No. 3 (2024)
Aerobic or Resistance Exercise for maximum Cardiovascular Disease Protection? An Appraisal of the Current Level of Evidence
Creators: name: Dimitriadis, Nikos
name: Panagiotakos, Demosthenes B
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2024
Subjects: Muscle Stretching Exercises, exercises, Muscle, Skeletal, Health Promotion.
Cardiovascular disease
exercise
Physical activity
Cardiovascular Disease

description: The beneficial role of physical activity on the cardiovascular system has been well established and appreciated.  The aim of this narrative review was to present a summary of the latest recommendations for physical activity, and to evaluate the most recent scientific evidence regarding the role of aerobic and or resistance exercise in relation to atherosclerotic cardiovascular disease (ASCVD) risk. The guidelines of major Organizations (i.e., European Society of Cardiology, American College of Cardiology/ American Heart Association, American College of Sports Medicine, and World Heart Federation, World Heart Organization) were also retrieved and presented here. Engagement in regular aerobic exercise is strongly recommended for all people and by all scientific organizations for reducing ASCVD mortality and morbidity. Resistance exercise should be implemented in addition to aerobic, however, its individual effects on ASCVD risk are not well established. A reduction of sedentary behavior at population level reduces the healthcare costs by multiple ways. Effective approaches should be implemented that include behavior theory-based interventions, e.g., goal-setting, re-evaluation of goals, self-monitoring, and feedback. Most important is to encourage activity that individuals enjoy and/or can be included in their daily life.
description: Journal of Preventive Medicine and Hygiene, Vol. 65 No. 3 (2024)
Гуманитарные технологии физической культуры и спорта
Creators: name: Батанцев Николай Иванович
name: Дудко Андрей Васильевич
Publisher: name: Международный журнал прикладных наук и технологий «Integral»
Year: 2020
Subjects: гуманитарные технологии
физическая культура
принципы

description: Последние исследования показали, что в области педагогики, социологии и психологии человека необходимо владение гуманитарными технологиями, которые помогают в понимании интересов и мотивов заинтересованных лиц. Необходимо выделить, что важной особенностью современных гуманитарных технологий является то, что чаще всего результатом, на получение которого они направлены, является та ли иная реакция человека, именно поэтому они могут использоваться и в физической культуре. При применении гуманитарных технологий происходит невольное принуждение обучающихся к определенному выбору поведения в данной среде, но при этом, создание ситуации, за счет которой выбор происходит естественно, действия участников физкультурно-образовательного процесса могут варьироваться и выбираться ими самостоятельно.
Spin and Orbital States and Their Phase Transitions of the Perovskite-Type Ti Oxides: Weak coupling Approach
Creators: name: Mochizuki, Masahito
Publisher: name: arXiv
Year: 2002
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The magnetic phase diagram of the perovskite-type Ti oxides as a function of the GdFeO3-type distortion is examined by using the Hartree-Fock analysis of a multiband d-p Hamiltonian from a viewpoint of competitions of the spin-orbit interaction, the Jahn-Teller (JT) level-splitting and spin-orbital superexchange interactions. Near the antiferromagnetic (AFM)-to-ferromagnetic (FM) phase boundary, A-type AFM [AFM(A)] and FM states accompanied by a certain type of orbital ordering are lowered in energy at large JT distortion, which is in agreement with the previous strong coupling study. With increasing the GdFeO3-type distortion, their phase transition occurs. Through this magnetic phase transition, the orbital state hardly changes, which induces nearly continuous change in the spin coupling along the c-axis from negative to positive. The resultant strong two-dimensionality in the spin coupling near the phase boundary is attributed to the strong suppression of T_N and T_C, which is experimentally observed. On the other hand, at small GdFeO3-type without JT distortions, which correspond to LaTiO3, the most stable solution is not G-type AFM [AFM(G)] but FM. Although the spin-orbit interaction has been considered to be relevant at the small or no JT distortion of LaTiO3 in the literature, our analysis indicates that the spin-orbit interaction is irrelevant to the AFM(G) state in LaTiO3 and superexchange-type interaction dominates. On the basis of further investigations on the nature of this FM state and other solutions, this discrepancy is discussed in detail.
description: 9 pages, 10 figures
Pycnogonidae Wilson 1878
Creators: name: Takahashi, Yoshie
name: Dick, Matthew H.
name: Mawatari, Shunsuke F.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Pycnogonida
Pantopoda
Pycnogonidae

description: FamilyPYCNOGONIDAE Wilson, 1878    Diagnosis. Species almost always very sturdy, with short, strong legs; chelifores and palps completely lacking; ovigers in males only, reduced in size, six- to nine-segmented, with large terminal claw and without strigilis, rarely entirely absent in both sexes (subgenus Anovigerum Stock); legs knobby, usually without but sometimes with tiny auxiliary claws. Cement glands usually not visible. Genital pores usually opening ventrally, though sometimes dorsally, on the second coxa. Contains eight- and 10-legged forms. Worldwide in distribution.
description: Published as part of Takahashi, Yoshie, Dick, Matthew H. & Mawatari, Shunsuke F., 2007, Sea spiders (Arthropoda: Pycnogonida) from waters adjacent to the Nansei Islands of Japan, pp. 61-79 in Journal of Natural History 41 (1 - 4) on page 72, DOI: 10.1080/00222930601121783, http://zenodo.org/record/5229875
Investigation of soil properties and pesticide intensity in crop lands at Tangail region of Bangladesh
Creators: name: TN Shila
name: MS Islam
name: MMM Hoque
name: MH Kabir
name: MR Jamil
name: U Kumar
name: TN Shila
name: MS Islam
name: MMM Hoque
name: MH Kabir
name: MR Jamil
name: U Kumar
Publisher: name: Unknown
Year: 2021
Subjects: subject: Crop Production/Industries
subject: Soil fertility
subject: Land use
subject: Pesticide intensity
subject: Organic matter

description: The study was conducted to investigate the soil properties and pesticide intensity in rice, banana and brinjal growing agricultural land of Delduar and Sakhipur upazila of Tangail district during July 2019 to June 2020. Forty five soil samples were collected from different crop land at the study area and analyzed in the Soil Resource Development Institute to determine the soil properties as pH, total organic matter (OM), total nitrogen (N), available phosphorus (P), available sulfur (S), available zinc (Zn), exchangeable potassium (K), exchangeable magnesium (Mg) and exchangeable calcium (Ca). However, pesticide used intensity was also evaluated through questionnaire survey with farmers and stakeholders in the study area. Results showed that pH, OM, available N, exchangeable Ca and exchangeable Mg content were significantly higher in rice growing land than banana and brinjal. On the other hand, available P, exchangeable K and available Zn content were substantially higher in brinjal growing land than rice and banana. The OM showed significant positive correlation with soil pH, available N, available S, exchangeable Mg and exchangeable Ca (r=0.37, 0.99, 0.31, 0.59 and 0.63, respectively), indicated rice growing land built up these soil properties through increasing soil OM. The available P showed significant and positive correlation with K and Zn (r=0.55 and 0.74, respectively), but negative correlation with exchangeable Mg and exchangeable Ca (r=-0.53 and -0.32, respectively). The exchangeable K showed significant and positive correlation with available Zn (r=0.45) but negative correlation with exchangeable Mg (r=-0.37). The Mg showed significant negative correlation with available Zn (r=-0.45) but positive correlation with exchangeable Ca (r=0.87). Results also revealed that pesticide used intensity was higher in brinjal followed by banana and minimum in rice crop. Study suggests that farmers require up-to-date information on soil nutrient status so that they may use the proper utilization of fertilizers and avoid using excessive amounts of fertilizers and pesticides in their crop land.
Биохимические физиологические причины актвиации панкреатических ферментов при стрессе организма
Creators: name: Арсаханова Гайна Абдулловна
Publisher: name: Международный журнал прикладных наук и технологий «Integral»
Year: 2020
Subjects: острый панкреатит
заболевание
ожирение
курение
факторы

description: В последнее время отдельным фактором развития как острого, так и хронического панкреатита также выделяют ожирение, курение. Выявлено, что приблизительно у 10% пациентов с острым панкреатитом, возникший впервые, и у 36% пациентов, имевших рецидив острого панкреатита, развивался хронический панкреатит, в 17% после первого эпизода острого панкреатита наблюдается рецидив, у 8% — заболевания прогрессирует в хроническую форму. Биохимическими признаками являются рост примерно в три раза активности амилазы (2-3 день) и липазы (7-14 день), хотя эти показатели не отражают тяжесть заболевания. Особенностью развития острого деструктивного панкреатита является то, что рано развивается иммунодефицит, следствием чего являются гнойно-некротические осложнения этого заболевания.
Two-Magnon Bound States in the Kitaev Model in a $[111]$-Field
Creators: name: Pradhan, Subhasree
name: Patel, Niravkumar D.
name: Trivedi, Nandini
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: It is now well established that the Kitaev honeycomb model in a magnetic field along the $[111]$-direction harbors an intermediate gapless quantum spin liquid (QSL) phase sandwiched between a gapped non-abelian QSL at low fields $H< H_{c1}$ and a partially polarized phase at high fields $H> H_{c2}$. Here, we analyze the low field and high field phases and phase transitions in terms of single- and two-magnon excitations using exact diagonalization (ED) and density matrix renormalization group (DMRG) methods. We find that the energy to create a bound state of two-magnons $Δ_p$ becomes lower than the energy to create a single spin flip $Δ_s$ near $H_{c2}$. In the entire Kitaev spin liquid $Δ_p
Additional file 4 of Identification and ranking of recurrent neo-epitopes in cancer
Creators: name: Blanc, Eric
name: Holtgrewe, Manuel
name: Arunraj Dhamodaran
name: Messerschmidt, Clemens
name: Willimsky, Gerald
name: Blankenstein, Thomas
name: Beule, Dieter
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 4 Overlap between recurrent variants and hotspot variants. The overlap is based on the codon position, so that all variants occurring at the same protein sequence position are pooled together. The recurrent variants that match the alternate codon definition in Chang et al. are added to the overlap. The recurrent variants are pooled by codon and sorted by decreasing occurrence frequency in the study. The overlap between hotspots and highly recurrent variants is high, and the common variants fraction decreases when recurrent variants become less frequent. The overlap between recurrent variants and the list of suspected false positive hotspots compiled by Chang et al. ([14]) is very limited. Inset: Venn diagram of the total overlap between the recurrent variants called in this study, and the hotspot variants described in Chang et al. ([14]).
The Likelihood of Positive Returns from Value-Added Calf Management Practices
Creators: name: Williams, Brian R.
name: DeVuyst, Eric A.
name: Peel, Derrell S.
name: Raper, Kellie Curry
name: Williams, Brian R.
name: DeVuyst, Eric A.
name: Peel, Derrell S.
name: Raper, Kellie Curry
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: beef production
subject: matching pairs
subject: nonparametric
subject: value-added management

description: Extension faculty have been educating cow-calf producers about value-added calf management programs and the premiums available at auction from these management practices for years. Despite these efforts, producers express doubt regarding the likelihood of premiums and the profitability of value-added management practices. We use matching pairs to calculate the difference in premiums and net returns between adopters and nonadopters and calculate the likelihood of positive net returns (and premiums) for individual practices and practice bundles. The probability of positive net returns ranges from 57% for dehorning to 79% for a certified vac-45 program (calves certified by a third party to be preconditioned for a minimum of 45 days, vaccinated, and dehorned) and probabilities increase with more practices adopted.
MOESM7 of Identification and ranking of recurrent neo-epitopes in cancer
Creators: name: Blanc, Eric
name: Holtgrewe, Manuel
name: Arunraj Dhamodaran
name: Messerschmidt, Clemens
name: Willimsky, Gerald
name: Blankenstein, Thomas
name: Beule, Dieter
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 7 Expected frequency of patients with at least one candidate not labelled as false positive. For each TCGA cohort, we have selected at random 1000 times 50%, 20%, 10% and 5% from the candidates, to conservately model a high rate of false positive within the candidates. From these selected candidates, we have computed the expected frequency of patients with a HLA-1 allele and a mutation matching at least one selected candidate.
Pycnogonum Brunnich 1764
Creators: name: Takahashi, Yoshie
name: Dick, Matthew H.
name: Mawatari, Shunsuke F.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Pycnogonida
Pantopoda
Pycnogonidae
Pycnogonum

description: Genus Pycnogonum Brunnich, 1764
 Diagnosis. Trunk and legs stout, with or without reticulation, usually lumpy overall; proboscis strong, usually barrel-shaped; abdomen short, horizontal; chelifores and palps completely lacking; ovigers in males only or lacking in both sexes, reduced in size, seven- to nine-segmented, without strigilis, with large terminal claw; legs very short, stout; tarsus, propodus, and sometimes tibiae often with short, bifurcate sole spines endally; main claw robust, well curved, generally without and sometimes with auxiliary claws. Cement glands unknown.
 Remarks. The genus Pycnogonum differs from most other pycnogonids in the strong, lumpy body, short legs, and absence of both chelifores and palps. This genus contains at least 68 known species and has a worldwide distribution. Six species have previously been reported from Japan, including Pycnogonum benokianum from shallow waters in the Nansei Island region (Ohshima 1935; Hedgpeth 1949; Child 1996).
description: Published as part of Takahashi, Yoshie, Dick, Matthew H. & Mawatari, Shunsuke F., 2007, Sea spiders (Arthropoda: Pycnogonida) from waters adjacent to the Nansei Islands of Japan, pp. 61-79 in Journal of Natural History 41 (1 - 4) on pages 72-73, DOI: 10.1080/00222930601121783, http://zenodo.org/record/5229875
Меланин в структуре противодействия стрессовым явлениям организма
Creators: name: Арсаханова Гайна Абдулловна
Publisher: name: Международный журнал прикладных наук и технологий «Integral»
Year: 2020
Subjects: доказательство
космическое излучение
грибки
бактерии
меланин

description: Меланины представляют собой группу пигментов, которые синтезируются во всех крупных таксонах как про-, так и эукариот. Их функция считается адаптивной, они обеспечивают приспособление живых организмов к условиям окружающей среды, стресса. Меланин придает окраску коже, волосам, ресницам, бровям, радужной оболочке глаза человека и отсутствует только у больных альбинизмом. Он образуется также в коже в ответ на действие утрафиолетового облучения, при этом выполняет защитную функцию, выступает антиоксидантом, что обеспечивается его строением. Меланин представляет собой полимер, который имеет способность задерживать и стабилизировать свободные радикалы и ксенобиотики как экзо-, так и эндогенного происхождения. В коже меланин не только защищает от ультрафиолетового излучения, но и от ионизирующего. Доказательством этого является то, что некоторые виды грибов, бактерий, имеющих бурые и черные меланиновые пигменты, живут в местах активного электрмагнитного, ультафиолетового, космического излучения, являются устойчивыми к рентгеновскому излучению.
Knowledge, attitude and practice of Lassa fever prevention among adults in Bali Local Government Area, Taraba State, Nigeria.
Creators: name: IGWE, Leaticia
name: Ibe, Sally Nkechinyere
name: Nyamsoh, Christopher Solomon
name: Nworuh, Blessed
name: Asinobi, Oluchi Goodness
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2024
Subjects: Knowledge, Practice, Attitude, Lassa fever prevention, Nigeria.
Descriptive study design and Cross sectional study design was used for this study. A simple and systematic random sampling technique was used to draw samples of 399 participants for the study. A structured questionnaire was used for data collection after being validated and its reliability tested. The data collected was analysed using frequencies, percentage the hypotheses were tested using Data analysis was done using SPSS version 21, frequency, mean standard deviation, and chi square were performed to ascertain the value of the variables the hypotheses were tested using chi-square statistics at ≤0.05 level of significance.

description: This study determined the level of knowledge, attitudes and practice of Lassa fever prevention among adults in Bali Local Government Area of Taraba State, Nigeria. A descriptive survey was employed for this cross sectional community based study. The target population was 176,634 and the sample size was 399 adults determined using TaroYamane’formula for finite population. A multi-staged sampling technique comprising simple and systematic random sampling techniques was used to select the respondents. The instrument for data collection was a structured questionnaire with reliability coefficient of 0.843. Data was analysed using SPSS version 21 and statistical tests included frequencies, percentage, mean standard deviation, while hypotheses were tested using chi square at ≤0.05 level of significance. Result revealed that 75% of the respondents had knowledge of the Lassa fever and the preventive practices and about 66.7% were aware of the varied preventive measures at their disposal. The study further shows that 56% had positive attitudes that could affect their practice of preventive measures of Lassa fever. The acceptability level according to this study was very high (89%) among the adults of Bali L.G.A in Taraba state. In conclusion, knowledge and attitudes were key in influencing the acceptability of any health-related programs, and consequently determines its adoption, if such knowledge and attitudes are utilized properly. The study therefore, recommends; educational intervention to improve the knowledge of Lassa fever among community members this will help towards its preventive practices.
description: Journal of Preventive Medicine and Hygiene, Vol. 65 No. 3 (2024)
Diagnostic pipeline and large-scale monitoring: the experience in the Apulian outbreak
Creators: name: Maria, Saponari
name: Percoco Anna
name: Caroppo Concetta
name: Francesco, Specchia
name: Stefania, Zicca
name: Loconsole Giuliana
name: Donato, Boscia
Publisher: name: Zenodo
Year: 2021
Subjects: subject: plant health
subject: xylella
subject: detection
subject: accuracy
subject: large-scale monitoring
subject: http://id.agrisemantics.org/gacs/C20262
subject: http://id.agrisemantics.org/gacs/C1157

description: In Apulia (southern Italy) since 2016 one of the largest monitoring campaign in EU is ongoing, with an average number of 100.000 samples tested per year in the framework of the official monitoring program for Xylella fastidiosa, in the demarcated and Xylella-free areas. More than 85% of the samples were from olive trees, the remaining from almond, oleander and other host plants. Before the promulgation of the EU Regulation 2020/1201, the diagnostic program was organized with two levels of checks. Samples were first screened in 4 regional laboratories by ELISA, with each laboratories processing 300-600 samples/day. Samples yielding positive or doubtful ELISA-results along with 3-5% of the negative samples, were re-tested by qPCR as confirmation tests and for verifying the lab performance for the serological tests. An average of 8.000 sample/year were re-tested by qPCR. Using this large dataset of samples (double tested by ELISA and qPCR) we determined the diagnostic specificity and sensitivity of the test used, and assessed the influence of other factors (period of sampling, origin of the samples). Overall, less than 0.03% of the ELISA-tested samples could not be assigned as negative/positive (i.e. undetermined) and thus re-tested by qPCR, yielding in the majority of the cases (>85%) negative qPCR-results. The diagnostic sensitivity and specificity calculated on the panel of ELISA-negative/positive samples re-tested in qPCR, approx. 26.000 samples, were 94% and 97%, respectively. These values did not vary significantly when the results were analyzed based on the period of sampling or location of the sampled trees. In conclusion, under the specific scenario characterizing the Apulian epidemics (olive predominant host plants, climatic conditions) this diagnostic workflow had allowed to screen with good diagnostic accuracy a relevant number of samples/year. Given the need to replace ELISA with qPCR tests, the capability of the laboratories to process the samples is now reduced (approx. half samples/day) and other possibilities will be consider for the implementation of the upcoming monitoring campaign (i.e testing pooled samples) to ensure testing the same amount of samples.
description: IT; PDF; donato.boscia@ipsp.cnr.it
Additional file 3 of Identification and ranking of recurrent neo-epitopes in cancer
Creators: name: Blanc, Eric
name: Holtgrewe, Manuel
name: Arunraj Dhamodaran
name: Messerschmidt, Clemens
name: Willimsky, Gerald
name: Blankenstein, Thomas
name: Beule, Dieter
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 3 Frequency of Single Nucleotides Variants (SNVs) that fall in a poly-A, poly-C, poly-G or poly-T sequence of length at least 6. The variants that appear only once in the whole study are colored in blue, while the variants that appear more than once are colored in red. The dotted line shows the expected fraction of such variants, if the sequences were all random. Except for the LIHC study, all variants that occur more than once in the cohort are found in difficult-to-sequence regions less than expected by chance.
Measurement of the azimuthal anisotropy of charged-particle production in Xe+Xe collisions at $\sqrt{s_{\mathrm{NN}}}=5.44$ TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2019
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: This paper describes the measurements of flow harmonics $v_2$-$v_6$ in 3 $μ\mathrm{b}^{-1}$ of Xe+Xe collisions at $\sqrt{s_{\mathrm{NN}}}=5.44$ TeV performed using the ATLAS detector at the LHC. Measurements of the centrality, multiplicity and $p_{\mathrm{T}}$ dependence of the $v_n$ obtained using two-particle correlations and the scalar product technique are presented. The measurements are also performed using a template-fit procedure, which was developed to remove non-flow correlations in small collision systems. This non-flow removal is shown to have a significant influence on the measured $v_n$ at high $p_{\mathrm{T}}$, especially in peripheral events. Comparisons of the measured $v_n$ with measurements in Pb+Pb collisions and $p$+Pb collisions at $\sqrt{s_{\mathrm{NN}}}=5.02$ TeV are also presented. The $v_n$ values in Xe+Xe collisions are observed to be larger than those in Pb+Pb collisions for $n=2$, 3 and 4 in the most central events. However, with decreasing centrality or increasing harmonic order $n$, the $v_n$ values in Xe+Xe collisions become smaller than those in Pb+Pb collisions. The $v_n$ in Xe+Xe and Pb+Pb collisions are also compared as a function of the mean number of participating nucleons, $\langle N_\text{part} \rangle$, and the measured charged-particle multiplicity in the detector. The $v_3$ values in Xe+Xe and Pb+Pb collisions are observed to be similar at the same $\langle N_\text{part}\rangle$ or multiplicity, but the other harmonics are significantly different. Comparisons of the $v_n$ measurements with theoretical calculations are also made.
description: 53 pages in total, author list starting page 37, 21 figures, 1 table, submitted to Phys. Rev. C. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2019-03/
A model and image based investigation of X. fastidiosa within host dynamics
Creators: name: Nancy, Walker
name: Kathryn, Rankin
name: Siul, Ruiz
name: Daniel, McKay Fletcher
name: Anne, Williams Katherine
name: Chiara, Petroselli
name: Pasquale, Saldarelli
name: Maria, Saponari
name: Steven, White
name: Tiina, Roose
Publisher: name: Zenodo
Year: 2021
Subjects: subject: plant health
subject: xylella
subject: http://id.agrisemantics.org/gacs/C20262
subject: http://id.agrisemantics.org/gacs/C1029

description: Xylella fastidiosa (X. fastidiosa) is a bacterium that colonises internal plant vascular networks causing pathogenic effects on several commercially important crops (e.g. olives, grapes, coffee, etc.). Despite a growing research effort since the recent detection of X. fastidiosa in Europe, the exact processes leading to X. fastidiosa disease symptoms are not fully understood due to difficulties in observing internal plant structures. Our goal is to utilise models to elucidate fundamental processes that lead to olive quick decline syndrome, the disease responsible for the devastating olive decline in Apulia, Southern Italy. We endeavour to do this by developing a fundamental mathematical modelling framework describing within-host biofilm development, and the resulting water-stresses that ultimately inhibit plant functionality and development. We have begun work on developing a fluid mechanics model that invokes a polymer-physical description of X.fastidiosa biofilm formation dynamics. Our approach is centred on the assumption that the biofilm structure is determined by the arrangement of extracellular polysaccharide (EPS) molecules. We have also produced X-ray Computed Tomography (XCT) images of both resistant and susceptible olive cultivars to determine possible morphological differences between the vascular networks of the cultivars. Preliminary modelling results of EPS dominant biofilm formation characterise biofilm coalescence in a consistent manner with early microfluidic controlled experiments and require fewer empirical assumptions. We intend to generate model domains with the XCT images and apply our theoretical frame work to simulate infection in actual vascular networks via image based modelling. We hope our work will improve the understanding of possible cultivar resistance mechanisms to enable informed breeding and effective replanting in Apulia, and that model simulations will provide insights for improving the efficiency of current sampling techniques.
description: GB; PDF; ncw1e19@soton.ac.uk
Управление пищевой безопасностью и рекультивация загрязненных земель
Creators: name: Нилиповский Василий Иванович
name: Бауржан Оралбекович Джанкуразов
name: Тлевхан Куромжанович Ахмеджанов
Publisher: name: Московский экономический журнал
Year: 2020
Subjects: пищевая безопасность
управление качеством продукции
загрязненные почвы
рекультивация земель
технологии восстановления нарушенных территорий

description: Качество сельскохозяйственной продукции как сложная функция, изменяется во времени в результате аддитивного действия физико-химических и биологических процессов связанных с экологией окружающей среды. К числу основных факторов деградации природной среды относится ее загрязнение тяжелыми металлами, особенно в районах горнодобывающих предприятий [1,2,3,4,5]. В работе приведены результаты исследований экологических показателей качества зерна пшеницы выращенной в окрестностях Соколовско-Сарбайского месторождения железных руд Костанайской области Республики Казахстан. Предлагается технология восстановления отработанных карьеров месторождений с применением метода полной засыпки их вскрышными породами с целью повышения эффективности восстановления земель сельскохозяйственного назначения [1,6,7,8].
Awareness of Lung Cancer Among the Lebanese General Population: a Cross-Sectional Study
Creators: name: Hmeidan, Mariam
name: Salameh, Pascale
name: Awada, Sanaa
name: Ajrouche, Roula
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2024
Subjects: lung cancer
Awareness
Cancer risk
Attitudes
LCAM
Non-Communicable disease
Lung cancer
Cancer awareness and prevention

description: Background. Lung cancer is a significant contributor to mortality worldwide. The aim of this study was to assess the level of lung cancer awareness among the Lebanese general population.

Methods. An online-based questionnaire was completed by 410 participants all over Lebanon. A validated Lung Cancer Awareness Measurement tool was used. Multivariate analysis using Generalized Linear model and post-hoc analysis were performed after assessing validity and reliability of the scale.

Results. Only 13.7% correctly identified age-related lung cancer risk, while 60.7% thought age was unrelated. Warning signs were poorly recalled, with persistent cough being the most remembered (58%), and coughing up blood being highly recognized (87.8%). Participants struggled to recognize persistent shoulder pain (28.7%) and finger/nail changes (29.51%) as possible warning signs of lung cancer. Multivariate analysis showed that governorates, educational level, and occupation significantly affected warning sign-scores. Post-hoc analysis revealed that people residing in Bekaa scored lower warning sign recognition scales compared with participants residing in Beirut, Mount Lebanon, and North. Postgraduates and medical field workers showed higher symptom recognition, with the latter scoring higher recall scales as well. Smoking was the most recalled and recognized risk factor (82% and 95.6%). Females, postgraduates, and medical workers showed higher risk factor recognition. While 75% were willing to seek medical attention for lung cancer suspicion, 58% lacked confidence in identifying warning signs.

Conclusions. Extensive awareness campaigns focusing on age-related misconceptions, warning signs, and risk factors hold immense promise for improved therapeutic outcomes.
description: Journal of Preventive Medicine and Hygiene, Vol. 65 No. 3 (2024)
Discrete versions of Gronwall's lemma and their application to the numerical analysis of parabolic problems
Creators: name: Emmrich, Etienne
Publisher: name: Technische Universität Berlin
Year: 1999
Subjects: subject: 510 Mathematik
subject: Gronwall-type inequality
subject: differential inequality
subject: difference inequality
subject: parabolic differential equation
subject: temporal discretization
subject: Euler method

description: The well-known Gronwall lemma often serves as a major tool for the analysis of time-dependent problems via energy methods. However, there is the need for a similar tool when considering temporal discretizations of evolutionary problems. With the paper in hand, the author wishes to give an overview of some discrete versions of the Gronwall lemma and presents a unified approach. In particular, new discrete versions of the lemma in its differential form and their application, showing decay behaviour for discretized parabolic problems, are studied. These versions give effective tools for the stability and error analysis of the temporal semi-discretization of parabolic problems covering non-homogeneous problems as well as approximations with variable step sizes.
Critical Behavior of Frustrated Josephson Junction Arrays with Bond Disorder
Creators: name: Yun, Young-Je
name: Baek, In-Cheol
name: Choi, Mu-Yong
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The scaling behavior of the current-voltage ($IV$) characteristics of a two-dimensional proximity-coupled Josephson junction array (JJA) with quenched bond disorder was investigated for frustrations $f=1/5$, 1/3, 2/5, and 1/2. For all these frustrations including 1/5 and 2/5 where a strongly first-order phase transition is expected in the absence of disorder, the $IV$ characteristics exhibited a good scaling behavior. The critical exponent $ν$ indicates that bond disorder may drive the phase transitions of frustrated JJA's to be continuous but not into the Ising universality class, contrary to what was observed in Monte Carlo simulations. The dynamic critical exponent $z$ for JJA's was found to be only 0.60 - 0.77.
description: RevTeX4, 4 pages, 4 figures, the manuscript is replaced with the published version
The Biggest Bang for the Buck: Valuation of Various Components of a Regional Promotion Campaign by Participating Restaurants
Creators: name: Xie, Ran
name: Isengildina-Massa, Olga
name: Carpio, Carlos E.
name: Xie, Ran
name: Isengildina-Massa, Olga
name: Carpio, Carlos E.
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Marketing
subject: FOS: Economics and business
subject: Research Methods/ Statistical Methods
subject: choice experiment
subject: mixed logit model
subject: local food willingness to pay

description: This study examined how various components of the Certified South Carolina campaign are valued by participating restaurants. A choice experiment was conducted to estimate the average willingness to pay (WTP) for each campaign component using a mixed logit model. Three existing campaign components—Labeling, Multimedia Advertising, and the ‘‘Fresh on the Menu’’ program—were found to have a significant positive economic value. Results also revealed that the type of restaurant, the level of satisfaction with the campaign, and the factors motivating participation significantly affected restaurants’ WTP for the campaign components.
Radio / X-ray correlation in the low/hard state of GX 339--4
Creators: name: Corbel, S.
name: Nowak, M. A.
name: Fender, R. P.
name: Tzioumis, A. K.
name: Markoff, S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the results of a long-term study of the black hole candidate GX 339-4 using simultaneous radio (from the Australia Telescope Compact Array) and X-ray (from the Rossi X-ray Timing Explorer and BeppoSAX) observations performed between 1997 and 2000. We find strong evidence for a correlation between these two emission regimes that extends over more than three decades in X-ray flux, down to the quiescence level of GX 339-4. This is the strongest evidence to date for such strong coupling between radio and X-ray emission. We discuss these results in light of a jet model that can explain the radio/X-ray correlation. This could indicate that a significant fraction of the X-ray flux that is observed in the low-hard state of black hole candidates may be due to optically thin synchrotron emission from the compact jet.
description: 8 pages. Accepted for publication in Astronomy & Astrophysics, 2003
Predicting State-Wide Votes on Ballot Initiatives to Ban Battery Cages and Gestation Crates
Creators: name: Smithson, Katie
name: Corbin, Max
name: Lusk, Jayson L.
name: Norwood, F. Bailey
name: Smithson, Katie
name: Corbin, Max
name: Lusk, Jayson L.
name: Norwood, F. Bailey
Publisher: name: Unknown
Year: 2014
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: International Relations/Trade
subject: animal welfare
subject: battery cage
subject: demographics
subject: gestation crate
subject: state initiatives

description: After California voters decided in a state initiative to ban gestation crates and battery cages, some are asking whether other states will host similar initiatives and if they will pass. This study addresses this question by using voting data in California to predict how voters in other states would respond to a similar initiative. Results suggest that a number of states allow such initiatives and possess a demographic profile favorable to the initiative’s passage. However, because these states host only a small portion of the livestock population, the impact of such initiatives on the well-being of farm animals is questionable.
Two-loop renormalization-group analysis of critical behavior at m-axial Lifshitz points
Creators: name: Shpot, M.
name: Diehl, H. W.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We investigate the critical behavior that d-dimensional systems with short-range forces and a n-component order parameter exhibit at Lifshitz points whose wave-vector instability occurs in a m-dimensional isotropic subspace of ${\mathbb R}^d$. Utilizing dimensional regularization and minimal subtraction of poles in $d=4+{m\over 2}-ε$ dimensions, we carry out a two-loop renormalization-group (RG) analysis of the field-theory models representing the corresponding universality classes. This gives the beta function $β_u(u)$ to third order, and the required renormalization factors as well as the associated RG exponent functions to second order, in u. The coefficients of these series are reduced to m-dependent expressions involving single integrals, which for general (not necessarily integer) values of $m\in (0,8)$ can be computed numerically, and for special values of m analytically. The $ε$ expansions of the critical exponents $η_{l2}$, $η_{l4}$, $ν_{l2}$, $ν_{l4}$, the wave-vector exponent $β_q$, and the correction-to-scaling exponent are obtained to order $ε^2$. These are used to estimate their values for d=3. The obtained series expansions are shown to encompass both isotropic limits m=0 and m=d.
description: 42 pages, 1 figure; to appear in Nuclear Physics B; footnote added, minor changes in v2
Higgs-mediated optical amplification in a non-equilibrium superconductor
Creators: name: Buzzi, Michele
name: Jotzu, Gregor
name: Cavalleri, Andrea
name: Cirac, J. Ignacio
name: Demler, Eugene A.
name: Halperin, Bertrand I.
name: Lukin, Mikhail D.
name: Shi, Tao
name: Wang, Yao
name: Podolsky, Daniel
Publisher: name: arXiv
Year: 2019
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The quest for new functionalities in quantum materials has recently been extended to non-equilibrium states, which are interesting both because they exhibit new physical phenomena and because of their potential for high-speed device applications. Notable advances have been made in the creation of metastable phases and in Floquet engineering under external periodic driving. In the context of non-equilibrium superconductivity, examples have included the generation of transient superconductivity above the thermodynamic transition temperature, the excitation of coherent Higgs mode oscillations, and the optical control of the interlayer phase in cuprates. Here, we propose theoretically a novel non-equilibrium phenomenon, through which a prompt quench from a metal to a transient superconducting state could induce large oscillations of the order parameter amplitude. We argue that this oscillating mode could act as a source of parametric amplification of the incident radiation. We report experimental results on optically driven K$_3$C$_{60}$ that are consistent with these predictions. The effect is found to disappear when the onset of the excitation becomes slower than the Higgs mode period, consistent with the theory proposed here. These results open new possibilities for the use of collective modes in many-body systems to induce non-linear optical effects.
description: 11 pages, 7 figures