cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Von der Vision in die Umsetzung - Kulturwandel und Change-Prozess am Beispiel eines umfangreichen Digitalisierungsprogramms
Creators: name: Pleyer, Conny
Publisher: name: TU Wien
Year: 2024
Subjects: subject: Digitalisierungsprogramm
subject: Kulturwandel
subject: Storytelling
subject: Change-Projekt
subject: Hierarchien
subject: Digitalization Program
subject: Cultural Change
subject: Storytelling
subject: Change Project
subject: Hierarchies

description: Arbeit an der Bibliothek noch nicht eingelangt - Daten nicht geprueft - gesperrte Arbeit (bis 2029-11-21+01:00)
description: Abweichender Titel nach Übersetzung der Verfasserin/des Verfassers
Genie: A new, fast, and outlier-resistant hierarchical clustering algorithm
Creators: name: Gagolewski, Marek
name: Bartoszuk, Maciej
name: Cena, Anna
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The time needed to apply a hierarchical clustering algorithm is most often dominated by the number of computations of a pairwise dissimilarity measure. Such a constraint, for larger data sets, puts at a disadvantage the use of all the classical linkage criteria but the single linkage one. However, it is known that the single linkage clustering algorithm is very sensitive to outliers, produces highly skewed dendrograms, and therefore usually does not reflect the true underlying data structure -- unless the clusters are well-separated. To overcome its limitations, we propose a new hierarchical clustering linkage criterion called Genie. Namely, our algorithm links two clusters in such a way that a chosen economic inequity measure (e.g., the Gini- or Bonferroni-index) of the cluster sizes does not drastically increase above a given threshold. The presented benchmarks indicate a high practical usefulness of the introduced method: it most often outperforms the Ward or average linkage in terms of the clustering quality while retaining the single linkage's speed. The Genie algorithm is easily parallelizable and thus may be run on multiple threads to speed up its execution even further. Its memory overhead is small: there is no need to precompute the complete distance matrix to perform the computations in order to obtain a desired clustering. It can be applied on arbitrary spaces equipped with a dissimilarity measure, e.g., on real vectors, DNA or protein sequences, images, rankings, informetric data, etc. A reference implementation of the algorithm has been included in the open source 'genie' package for R. See also https://genieclust.gagolewski.com for a new implementation (genieclust) -- available for both R and Python.
Recurrent dendrodendritic inhibition of accessory olfactory bulb mitral cells requires activation of group I metabotropic glutamate receptors.
Creators: name: Castro, Jason B.
name: Hovis, Kenneth R.
name: Urban, Nathan
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Metabotropic glutamate receptors (mGluRs) modulate neural excitability and network tone in many brain regions. Expression of mGluRs is particularly high in the accessory olfactory bulb (AOB), a CNS structure critical for detecting chemicals that identify kin and conspecifics. Because of its relative simplicity and its direct projection to the hypothalamus, the AOB provides a model system for studying how mGluRs affect the flow of encoded sensory information to downstream areas. We investigated the role of group I mGluRs in synaptic processing in AOB slices and found that under control conditions, recurrent inhibition of principal neurons (mitral cells) was completely eliminated by the mGluR1 antagonist LY367385 [(S)-(+)-alpha-amino-4-carboxy-2 methylbenzeneacetic acid]. In addition, the group I mGluR agonist DHPG [(S)-3,5-dihydroxyphenylglycine; 20 microM] induced a dramatic increase in the rate of spontaneous IPSCs. This increase was dependent on voltage-gated calcium channels but persisted even after blockade of ionotropic glutamatergic transmission and sodium channels. Together, these results indicate that mGluR1 plays a critical role in controlling information flow through the AOB and suggest that mGluR1 may be an important locus for experience-dependent changes in synaptic function.
Strategies and guidelines for urban sustainability: the explosion of micromobility from Covid-19
Creators: name: Gaglione, Federica
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: Starting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always following a rigorous scientific in-depth analysis. This section of the Journal, Review Notes, is the expression of a continuous updating of emerging topics concerning relationships among urban planning, mobility and environment, through a collection of short scientific papers written by young researchers. The Review Notes are made of five parts. Each section examines a specific aspect of the broader information storage within the main interests of TeMA Journal. In particular: the Town Planning International Rules and Legislation Overview section aims at presenting the latest updates in the territorial and urban legislative sphere. Urban patterns and their intrinsic relationships have completely changed since Covid-19. In particular, the mobility subsystem has undergone a significant change, inducing users to use "soft" such as micromobility. Micromobility is now on the rise, especially in large cities, but at the same time the lack of dedicated routes pushes researchers and technicians in the area to find solutions capable of providing rules to users. This section examines the legislative decrees issued by the Italian government to promote a sustainable mode of travel for cities such as micromobility.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
Many-body theories of density response for a strongly correlated Fermi gas
Creators: name: Hu, Hui
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Recent breakthroughs in the creation of ultra-cold atomic gases in the laboratory have ushered in major changes in physical science. Many novel experiments are now possible, with an unprecedented control of interaction, geometry and purity. Quantum many-body theory is facing severe challenges in quantitatively understanding new experimental results. Here, we review some recently developed theoretical techniques that provide successful predictions for density response of a strongly correlated atomic Fermi gas. These include the strong-coupling random-phase approximation theory, high-temperature quantum virial expansion, and asymptotically exact Tan relations applicable at large momentum.
description: 11 pages, 10 figures, invited review paper for Frontiers of Physics (2012)
Site mutations disrupt inter-helical H-bonds (alpha14W-alpha67T and beta15W-beta72S) involved in kinetic steps in the hemoglobin R-->T transition without altering the free energies of oxygenation.
Creators: name: Ching-Hsuan  Tsai
name: Simplaceanu, Virgil
name: Ho, Nancy T.
name: Tong-Jian  Shen
name: Daojing  Wang
name: Spiro, Thomas G.
name: Ho, Chien
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Three recombinant mutant hemoglobins (rHbs) of human normal adult hemoglobin (Hb A), rHb (alphaT67V), rHb (betaS72A), and rHb (alphaT67V, betaS72A), have been constructed to test the role of the tertiary intra-subunit H-bonds between alpha67T and alpha14W and between beta72S and beta15W in the cooperative oxygenation of Hb A. Oxygen-binding studies in 0.1 M sodium phosphate buffer at 29 degrees C show that rHb (alphaT67V), rHb (betaS72A), and rHb (alphaT67V, betaS72A) exhibit oxygen-binding properties similar to those of Hb A. The binding of oxygen to these rHbs is highly cooperative, with a Hill coefficient of approximately 2.8, compared to approximately 3.1 for Hb A. Proton nuclear magnetic resonance (NMR) studies show that rHb (alphaT67V), rHb (betaS72A), rHb (alphaT67V, betaS72A), and Hb A have similar quaternary structures in the alpha(1)beta(2) subunit interfaces. In particular, the inter-subunit H-bonds between alpha42Tyr and beta99Asp and between beta37Trp and alpha94Asp are maintained in the mutants in the deoxy form. There are slight perturbations in the distal heme pocket region of the alpha- and beta-chains in the mutants. A comparison of the exchangeable 1H resonances of Hb A with those of these three rHbs suggests that alpha67T and beta72S are H-bonded to alpha14W and beta15W, respectively, in the CO and deoxy forms of Hb A. The absence of significant free energy changes for the oxygenation process of these three rHbs compared to those of Hb A, even though the inter-helical H-bonds are abolished, indicates that these two sets of H-bonds are of comparable strength in the ligated and unligated forms of Hb A. Thus, the mutations at alphaT67V and betaS72A do not affect the overall energetics of the oxygenation process. The preserved cooperativity in the binding of oxygen to these three mutants also implies that there are multiple interactions involved in the oxygenation process of Hb A.
The phased telomere-to-telomere reference genome of Musa acuminata, a main contributor to banana cultivars
Creators: name: Liu, Xin
name: Arshad, Rida
name: Wang, Xu
name: Li, Wei-Ming
name: Zhou, Yongfeng
name: Ge, Xue-Jun
name: Huang, Hui-Run
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 310509
subject: Genomics
classificationCode: 310510
subject: Molecular evolution

description: Musa acuminata is a main wild contributor to banana cultivars. Here, we reported a haplotype-resolved and telomere-to-telomere reference genome of M. acuminata by incorporating PacBio HiFi reads, Nanopore ultra-long reads, and Hi-C data. The genome size of the two haploid assemblies was estimated to be 469.83 Mb and 470.21 Mb, respectively. Multiple assessments confirmed the contiguity (contig N50: 16.53Mb and 18.58Mb; LAI: 20.18 and 19.48), completeness (BUSCOs: 98.57% and 98.57%), and correctness (QV: 45.97 and 46.12) of the genome. The repetitive sequences accounted for about half of the genome size. In total, 40,889 and 38,269 protein-coding genes were annotated in the two haploid assemblies, respectively, of which 9.56% and 3.37% were newly predicted. Genome comparison identified a large reciprocal translocation involving 3 Mb and 10 Mb from chromosomes 01 and 04 within M. acuminata. This reference genome of M. acuminata provides a valuable resource for further understanding of subgenome evolution of Musa species, and precise genetic improvement of banana.
The contribution of a tramway to pedestrian vitality
Creators: name: Zacharias, John
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: Pedestrian movement in the public environment is important in supporting local public life, commerce and physical activity. Countering the decline in the presence of people on the streets is a major focus of urban planning in a wide variety of urban contexts. This research investigates the contribution of a tramway to local pedestrian movement, using the Hong Kong Tramway (HKT) as a case. Flow counts were collected in a field study of the tram corridor that enabled regression analysis. Pedestrian flow was positively related to the following, in descending order of importance: feeder street pedestrian flow, tram alighting rates and irregular crossing rates. These factors cumulatively account for 39% of pedestrian volume on tram corridor segments. Pedestrian flow is negatively related to the degree of barrier fencing and block size. The tram is also used to transit between walking segments, effectively enlarging the individual walking environment. The findings suggest spatial planning measures associated with higher pedestrian flow.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
Stochastic steady state gain in a gene expression process with mRNA degradation control.
Creators: name: Kuwahara, Hiroyuki
name: Schwartz, Russell
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Recent analyses with high-resolution single-molecule experimental methods have shown highly irregular and variable bursting of mRNA in a wide range of organisms. Noise in gene expression is thought to be beneficial in cell fate specifications, as it can lay a foundation for phenotypic diversification of isogenetic cells in the homogeneous environment. However, because the stability of proteins is, in many cases, higher than that of mRNAs, noise from transcriptional bursting can be considerably buffered at the protein level, limiting the effect of noisy mRNAs at a more global regulation level. This raises a question as to what constructive role noisy mRNAs can play in the system-level dynamics. In this study, we have addressed this question using the computational models that extend the conventional transcriptional bursting model with a post-transcriptional regulation step. Surprisingly, by comparing this stochastic model with the corresponding deterministic model, we find that intrinsic fluctuations can substantially increase the expected mRNA level. Because effects of a higher mRNA level can be transmitted to the protein level even with slow protein degradation rates, this finding suggests that an increase in the protein level is another potential effect of transcriptional bursting. Here, we show that this striking steady state increase is caused by the asynchronous nature of molecular reactions, which allows the transcriptional regulation model to create additional modes of qualitatively distinct dynamics. Our results illustrate non-intuitive effects of reaction asynchronicity on system dynamics that cannot be captured by the traditional deterministic framework. Because molecular reactions are intrinsically stochastic and asynchronous, these findings may have broad implications in modelling and understanding complex biological systems.
After recovery: new urban emergencies
Creators: name: Guida, Carmen
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: Starting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always remaining in the groove of rigorous scientific in-depth analysis. This section of the Journal, Review Notes, is the expression of a continuous updating of emerging topics concerning relationships between urban planning, mobility and environment, through a collection of short scientific papers written by young researchers. The Review Notes are made of four parts. Each sections examines a specific aspect of the broader information storage within the main interests of TeMA Journal. In particular, the Urban planning literature review section aims at presenting recent books and journals, within global scientific panorama, on selected topics and issues. This contribution aims at discussing the main impacts and consequences of the Covid-19 pandemic on our lives and urban systems. While for the last issue of TeMA, this section of the journal was dedicated to the emergency phase, according to the new policy and strategic actions aimed at improving the coexistence of the new coronavirus within urban environments, this contribution is focused on how policy makers can enhance urban resilience, in sight of potential new health crisis.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
A Characterization of Deterministic Sampling Patterns for Low-Rank Matrix Completion
Creators: name: Pimentel-Alarcón, Daniel L.
name: Boston, Nigel
name: Nowak, Robert D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: Algebraic Geometry (math.AG)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Low-rank matrix completion (LRMC) problems arise in a wide variety of applications. Previous theory mainly provides conditions for completion under missing-at-random samplings. This paper studies deterministic conditions for completion. An incomplete $d \times N$ matrix is finitely rank-$r$ completable if there are at most finitely many rank-$r$ matrices that agree with all its observed entries. Finite completability is the tipping point in LRMC, as a few additional samples of a finitely completable matrix guarantee its unique completability. The main contribution of this paper is a deterministic sampling condition for finite completability. We use this to also derive deterministic sampling conditions for unique completability that can be efficiently verified. We also show that under uniform random sampling schemes, these conditions are satisfied with high probability if $O(\max\{r,\log d\})$ entries per column are observed. These findings have several implications on LRMC regarding lower bounds, sample and computational complexity, the role of coherence, adaptive settings and the validation of any completion algorithm. We complement our theoretical results with experiments that support our findings and motivate future analysis of uncharted sampling regimes.
description: This update corrects an error in version 2 of this paper, where we erroneously assumed that columns with more than r+1 observed entries would yield multiple independent constraints
Project role for climate change in the urban regeneration. Reinventing cities winning projects in Milan and Rome
Creators: name: Strippoli, Veronica
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: The effects of the climate change employ a strong impact on the city and on the inhabitants, in fact the risk appears to be particularly clear in the metropolis. The urban setting fulfils a leading role in the consequences on the climate situation and the cities turn out to be the mainly responsible for the emissions of pollutants. In this situation the urban regeneration, as an opportunity to operate on the city’s “wounds” through an accurate plan, tries to improve the reactions of the urban territory even in terms of environmental sustainability. Becomes particularly important summarising the different kinds of knowledge of the various disciplines to assure the management of complex processes, like those of the transforming city that need a new way to intervene in the urban project. The urban regeneration is a “multidisciplinary container” that can efficaciously face the needs of the territory, a way to obtain the urban quality. The Italian metropolis manifest the will to align to the international expectations through the implementation of targeted urban regeneration built-in programs. The Reinventing Cities projects present solutions attributable to those typological features necessary by now in the sustainable urban regeneration projects, showing vision of a renewed architectural projects.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
From discrete elements to continuum fields: Extension to bidisperse systems
Creators: name: Tunuguntla, Deepak R.
name: Thornton, Anthony R.
name: Weinhart, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Computation (stat.CO)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: To develop, calibrate and/or validate continuum models from experimental or numerical data, micro-macro transition methods are required. These methods are used to obtain the continuum fields (such as density, momentum, stress) from the discrete data (positions, velocities, forces). This is especially challenging for non-uniform and dynamic situations in the presence of multiple components. Here, we present a general method to perform this micro-macro transition, but for simplicity we restrict our attention to two-component scenarios, e.g. particulate mixtures containing two types of particles. We present an extension to the micro-macro transition method, called \emph{coarse-graining}, for unsteady two-component flows. By construction, this novel averaging method is advantageous, e.g. when compared to binning methods, because the obtained macroscopic fields are consistent with the continuum equations of mass, momentum, and energy balance. Additionally, boundary interaction forces can be taken into account in a self-consistent way and thus allow for the construction of continuous stress fields even within one particle radius of the boundaries. Similarly, stress and drag forces can also be determined for individual constituents of a multi-component mixture, which is essential for several continuum applications, \textit{e.g.} mixture theory segregation models. Moreover, the method does not require ensemble-averaging and thus can be efficiently exploited to investigate static, steady, and time-dependent flows. The method presented in this paper is valid for any discrete data, \textit{e.g.} particle simulations, molecular dynamics, experimental data, etc.
description: Published in the special issue -Modelling and computational challenges in granular materials- of the journal -Computational Particle Mechanics-
Structural plasticity within the barrel cortex during initial phases of whisker-dependent learning.
Creators: name: Kuhlman, Sandra
name: O'Connor, Daniel H.
name: Fox, Kevin
name: Svoboda, Karel
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: We report learning-related structural plasticity in layer 1 branches of pyramidal neurons in the barrel cortex, a known site of sensorimotor integration. In mice learning an active, whisker-dependent object localization task, layer 2/3 neurons showed enhanced spine growth during initial skill acquisition that both preceded and predicted expert performance. Preexisting spines were stabilized and new persistent spines were formed. These findings suggest rapid changes in connectivity between motor centers and sensory cortex guide subsequent sensorimotor learning.
Spatial policy in cities during the Covid-19 pandemic in Poland
Creators: name: Śleszyński, Przemysław
name: Nowak, Maciej
name: Blaszke, Małgorzata
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: The ‘geographic’ aim of the study is to find the regularity of the increase in the number of infections in larger cities and their surroundings. The goal related to the science of public policy is to determine the implemented and potential effects related to spatial policy in Polish cities. The geographic part of this publication uses the available data on the development of the number of identified (recorded) infections. The part of the paper related to the accomplishment of the goal covering the sphere of public policy is primarily of an overview nature. It contains the characteristics of the spatial management system in Poland (including tools affecting the broadest impact on urban space) and the introduced and potential changes caused by the pandemic.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
MPEC 2023-O99 : 2023 OX3
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 OX3

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
CAIBC: Capturing All-round Information Beyond Color for Text-based Person Retrieval
Creators: name: Wang, Zijie
name: Zhu, Aichun
name: Xue, Jingyi
name: Wan, Xili
name: Liu, Chao
name: Wang, Tian
name: Li, Yifeng
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Information Retrieval (cs.IR)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: Given a natural language description, text-based person retrieval aims to identify images of a target person from a large-scale person image database. Existing methods generally face a \textbf{color over-reliance problem}, which means that the models rely heavily on color information when matching cross-modal data. Indeed, color information is an important decision-making accordance for retrieval, but the over-reliance on color would distract the model from other key clues (e.g. texture information, structural information, etc.), and thereby lead to a sub-optimal retrieval performance. To solve this problem, in this paper, we propose to \textbf{C}apture \textbf{A}ll-round \textbf{I}nformation \textbf{B}eyond \textbf{C}olor (\textbf{CAIBC}) via a jointly optimized multi-branch architecture for text-based person retrieval. CAIBC contains three branches including an RGB branch, a grayscale (GRS) branch and a color (CLR) branch. Besides, with the aim of making full use of all-round information in a balanced and effective way, a mutual learning mechanism is employed to enable the three branches which attend to varied aspects of information to communicate with and learn from each other. Extensive experimental analysis is carried out to evaluate our proposed CAIBC method on the CUHK-PEDES and RSTPReid datasets in both \textbf{supervised} and \textbf{weakly supervised} text-based person retrieval settings, which demonstrates that CAIBC significantly outperforms existing methods and achieves the state-of-the-art performance on all the three tasks.
description: Accepted on ACM MM '22
title: A method for evaluating air barrier systems and materials
Creators: name: Di Lenardo, B.
Publisher: name: National Research Council of Canada. Institute for Research in Construction
Year: 2000
Subjects: subject: Air and vapour barriers
valueUri: urn:ircsubjects:IRC0310
subject: Pare-vapeur et pare-air
valueUri: urn:ircsubjects:IRC0310

description: The air barrier system is a key to the effective performance of the building envelope. Its importance in controlling the transfer of heat, air and moisture is reflected in requirements in the National Building Code. Although this role has been recognized for more than forty years, the industry did not have a generally recognized test method to evaluate whether an innovative air barrier system would meet the intents of the NBC requirements. Enter the Canadian Construction Materials Centre (CCMC). CCMC, with the support of industry partners and IRC researchers, developed a test method that enables a manufacturer to determine whether its innovative air barrier system meets the intents of the NBC requirements. This Update reviews the NBC requirements for air barrier systems, explains the test method and shows how it applies to three-storey buildings.
description: Le système d'étanchéité à l'air est un élément déterminant dans la performance de l'enveloppe du bâtiment. Son importance dans le contrôle du passage de la chaleur, de l'air et de l'humidité à travers l'enveloppe du bâtiment est d'ailleurs soulignée dans les exigences du Code national du bâtiment. Bien que ce rôle soit reconnu depuis plus de 40 ans maintenant, l'industrie n'avait pas jusqu'à présent une méthode d'essai reconnue pour évaluer si un système d'étanchéité à l'air novateur respecte l'esprit du CNB. Le Centre canadien des matériaux de construction (CCMC) aux côtés des chercheurs de l'IRC et des partenaires de l'industrie a alors mis au point une méthode qui permet aux fabricants de savoir si leurs systèmes novateurs d'étanchéité à l'air sont bien conformes aux exigences du CNB. Ce numéro passe en revue les exigences en question du CNB, explique la méthode d'évaluation et montre comment elle peut s'appliquer à un bâtiment de trois étages.
Land surface temperature and land cover dynamics. A study related to Sardinia, Italy
Creators: name: Leone, Federica
name: Lai, Sabrina
name: Zoppi, Corrado
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: This study aims at analyzing analogies and differences between the spatial relations regarding land surface temperature (LST) and land covers in May and August 2019. Land cover data are drawn from the most updated spatial datasets available from Copernicus, while LST is retrieved from Landsat 8 satellite images made available by the U.S. Geological Survey. The methodology couples GIS spatial analysis and regression analysis; the latter is used to implement spatial inferential analysis as regards LST. Moreover, on the basis of a “what if” assessment, the impact of future afforestation, as regards rural areas, is detected with respect to decrease in LST, building on the outcomes of the model which relates LST to land cover types. The Sardinian region is taken as case study because its climate homogeneity and its self-containment allow for a pretty straightforward identification of the regional boundaries. The correlation between the spatial distribution of LST and land cover reveals, in the two time periods, that urbanization and the spatial dynamics of heating phenomena are closely connected. The methodology can be easily implemented in other regional contexts, and comparison of analogies and differences are quite effective and useful in identifying stylized facts and policy implications.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
title: The 18th Kilbrandon Lecture (University of Strathclyde, 18 February 2021) : Labours of love: the crisis of care
Creators: name: Bunting, Madeleine
Publisher: name: Strathprints - University of Strathclyde
Year: 2021

description: This lecture was arranged during the COVID-19 pandemic and during a period of government-imposed restrictions to normal life. Only essential shops were open. Schools, colleges and universities were mostly closed, and learning moved online. The lecture itself was live-streamed, as a webinar, to an audience of around 500 watching from their own homes. The lecture was based on Ms Bunting's research for her 2020 book, 'Labours of Love: The Crisis of Care'. She spoke about how care has been marginalised and the skills required to perform it widely undervalued, even by carers themselves. The pandemic brought the work of carers to centre-stage. While health and social care services had been underfunded for decades, a war-chest was found to fight the virus and its consequences. Ms Bunting pointed out that the vast amount of caring work, paid and unpaid, falls to women. 'Care is the feminist issue; it profoundly shapes women's lives at home and at work.' The lecture was followed by commentaries by University of Strathclyde academics Dr Graham Connelly and Dr Laura Steckley, and a vote of thanks by Minister for Children and Early Years in the Scottish Government, Ms Maree Todd MSP.
Structured association analysis leads to insight into Saccharomyces cerevisiae gene regulation by finding multiple contributing eQTL hotspots associated with functional gene modules.
Creators: name: Curtis, Ross E.
name: Seyoung  Kim
name: Woolford, John
name: Wenjie  Xu
name: Xing, Eric P
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: BACKGROUND: Association analysis using genome-wide expression quantitative trait locus (eQTL) data investigates the effect that genetic variation has on cellular pathways and leads to the discovery of candidate regulators. Traditional analysis of eQTL data via pairwise statistical significance tests or linear regression does not leverage the availability of the structural information of the transcriptome, such as presence of gene networks that reveal correlation and potentially regulatory relationships among the study genes. We employ a new eQTL mapping algorithm, GFlasso, which we have previously developed for sparse structured regression, to reanalyze a genome-wide yeast dataset. GFlasso fully takes into account the dependencies among expression traits to suppress false positives and to enhance the signal/noise ratio. Thus, GFlasso leverages the gene-interaction network to discover the pleiotropic effects of genetic loci that perturb the expression level of multiple (rather than individual) genes, which enables us to gain more power in detecting previously neglected signals that are marginally weak but pleiotropically significant.
RESULTS: While eQTL hotspots in yeast have been reported previously as genomic regions controlling multiple genes, our analysis reveals additional novel eQTL hotspots and, more interestingly, uncovers groups of multiple contributing eQTL hotspots that affect the expression level of functional gene modules. To our knowledge, our study is the first to report this type of gene regulation stemming from multiple eQTL hotspots. Additionally, we report the results from in-depth bioinformatics analysis for three groups of these eQTL hotspots: ribosome biogenesis, telomere silencing, and retrotransposon biology. We suggest candidate regulators for the functional gene modules that map to each group of hotspots. Not only do we find that many of these candidate regulators contain mutations in the promoter and coding regions of the genes, in the case of the Ribi group, we provide experimental evidence suggesting that the identified candidates do regulate the target genes predicted by GFlasso.
CONCLUSIONS: Thus, this structured association analysis of a yeast eQTL dataset via GFlasso, coupled with extensive bioinformatics analysis, discovers a novel regulation pattern between multiple eQTL hotspots and functional gene modules. Furthermore, this analysis demonstrates the potential of GFlasso as a powerful computational tool for eQTL studies that exploit the rich structural information among expression traits due to correlation, regulation, or other forms of biological dependencies.
title: Curling of concrete slabs on grade
Creators: name: Mailvaganam, N. P.
name: Springfield, J.
name: Repette, W. L.
name: Taylor, D. A.
Publisher: name: National Research Council of Canada. Institute for Research in Construction
Year: 2000
Subjects: subject: Concrete
valueUri: urn:ircsubjects:IRC0740
subject: Béton
valueUri: urn:ircsubjects:IRC0740

description: Concrete slabs on grade tend to curl up at joints and around the perimeter. As a result, floors in industrial and commercial buildings may deteriorate rapidly, causing safety problems and requiring repairs. This Update reviews the basic cause of curling - differential shrinkage produced as the exposed top surface shrinks and the core does not. Factors affecting the amount of curling are listed and discussed, along with possible preventive measures. Readers are advised that, although it is possible to repair most slabs, curling should be minimized by careful control of concrete mix composition and handling. Options are explained for controlling curling, preventing damage to curled slabs and deciding on a repair strategy. Finally, various methods of repair for different situations are discussed.
description: Les dalles de fondation en béton ont tendance à se soulever aux joints et le long de leur périmètre. Résultat, les planchers des bâtiments commerciaux et industriels risquent de se détériorer rapidement ce qui entraîne des réparations et des problèmes de sécurité. Cet article passe en revue les principales causes du gauchissement comme le retrait différentiel qui se produit lorsque la surface exposée de la dalle se rétracte alors que le noyau lui ne bouge pas. Les facteurs influençant l'ampleur du gauchissement d'une dalle sont répertoriés et analysés ainsi que les mesures de prévention possibles. Il est presque toujours possible de réparer les dalles mais il vaut mieux minimiser les risques de gauchissement en contrôlant notamment la composition et la manutention du mélange de béton. Les auteurs expliquent comment contrôler le gauchissement, comment prévenir les dommages et opter pour une stratégie de réparation. Enfin, ils présentent plusieurs méthodes de réparation en fonction de situations données.
Subcompartmentalizing the Golgi apparatus.
Creators: name: Manojkumar Puthenveedu
name: Linstedt, Adam
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The subcompartmentalized structure of the Golgi apparatus contributes to efficient glycosylation in the secretory pathway. Subcompartmentalization driven by maturation relies primarily on constant and accurate vesicle-mediated local recycling of Golgi residents. The precision of this vesicle transport is dependent on the interplay between the key factors that mediate vesicle budding and fusion--the coat proteins and the SNARE fusion machinery. These alone, however, may not be sufficient to ensure establishment of compartments de novo, and additional regulatory mechanisms operate to modify their activity.
title: Considerations in the design of smoke management systems for atriums
Creators: name: Lougheed, G. D.
Publisher: name: National Research Council of Canada. Institute for Research in Construction
Year: 2000
Subjects: subject: Atriums
valueUri: urn:ircsubjects:IRC0442
subject: Atriums
valueUri: urn:ircsubjects:IRC0442

description: An engineered approach to designing smoke management systems for atrium buildings can play a role in extending the use of an atrium space. Such an approach, based on the principles of atrium smoke management outlined in Construction Technology Update No. 47, can be used to meet the requirements of applicable building codes for a particular building use and design. This Update discusses various engineered approaches to the design of smoke management systems, which typically involve the use of mechanical exhaust systems to limit the accumulation and migration of smoke.
description: Une approche technique en matière de conception de système de gestion de la fumée pour les bâtiments pourvus d'atriums peut permettre d'élargir l'utilisation des atriums. Une telle approche, basée sur les principes de la gestion de la fumée dans les atriums qui ont été évoqués dans Solution constructive n° 47, permet en outre de respecter les exigences des codes du bâtiment qui s'appliquent pour une utilisation et une conception de bâtiment données. Cet article traite des différentes approches techniques en matière de conception de systèmes de gestion de la fumée, lesquels mettent habituellement en jeu des systèmes d'évacuation mécaniques pour réduire l'accumulation et la migration de la fumée.
Causes of residential mobility and Turkey practice
Creators: name: Özlü, Seda
name: Beyazli, Dilek
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: Residential mobility is an economic and social recovery process that determines urban growth and regional development. The urban population relocates due to the events in their lives or their dissatisfaction with the conditions. Such individual movements play a role in the construction of urban geography. The aim of the present study was to discuss the factors that affect the residential mobility in Ortahisar district in Trabzon, Turkey. To determine the mobility, a survey was conducted with 445 individuals in 11 neighborhoods with different socio-demographic, economic and physical attributes in Trabzon urban center. The survey findings were analyzed based on a) the analysis of the socio-demographic structure of households, b) evaluation of the residential buildings, c) the analysis of historical mobility, and d) the assessments of causality in mobility. In the study, the causal factors were analyzed based on the life cycle, life course and satisfaction approaches and mobility classification available in the literature, and the study findings were analyzed with descriptive statistics. It was determined that residential ownership, the structure of the household members, and proximity to the workplace factors were effective on residential mobility in Trabzon.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
РАННИЕ БИОМАРКЕРЫ ДИАБЕТИЧЕСКОЙ БОЛЕЗНИ ПОЧЕК
Creators: name: Шагазатова, Барно
name: Рахимбердиева, Зиёда
Publisher: name: Zenodo
Year: 2024

description: Диабетическая болезнь почек (ДБП) является широко распространенным заболеванием во всем мире. Она представляет собой одно из наиболее распространенных осложнений сахарного диабета (СД) и является ведущей причиной болезни почек в терминальной стадии болезни почек (ТСБП). В его развитии участвуют три фундаментальных компонента: гемодинамическая, метаболическая и воспалительная. С клинической точки зрения, постоянная альбуминурия в сочетании с прогрессирующим снижением скорости гломерулярной фильтрации (СКФ) определяет это заболевание. Однако, поскольку эти изменения не являются специфичными для ДБП, необходимо обсудить новые биомаркеры, возникающие в процессе патогенеза заболевания, которые могут помочь в диагностике, наблюдении, лечении и прогнозе заболевания.
A GIS-based automated procedure to assess disused areas
Creators: name: Francini, Mauro
name: Margiotta, Nicole
name: Palermo, Annunziata
name: Viapiana, Maria Francesca
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: Regeneration of disused sites represents a significant opportunity. The scientific interest in their redevelopment possibilities has grown considerably in recent years. Despite this, a shared definition of disused sites which goes beyond that of brownfields and allows recognition the size of the problem on a transnational scale is still lacking. This study provides an overview of the main definitions provided by scientific literature and on this basis, it proposes a parametric definition of functionally disused areas. Subsequently, a GIS-based operational tool able to map functionally disused areas through a progressive screening of the local territory is introduced. The proposed methodology is tested on two Italian municipalities. It is the first step of a research aimed at defining a wider process able to assess the possibility of converting disused areas into multifunctional or monofunctional “smart” districts. They could be, indeed, characterized by a mixed use – contributing to soil consumption reduction – or by a single use – “social infrastructures” – linked to the needs that emerged as result of Covid 19 pandemic. This assessment process, hence, could support urban planning both at ordinary and emergency phase, allowing to identify in very short time areas where temporary facilities could be installed.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
The Covid-19 pandemic from the elderly perspective in urban areas: An evaluation of urban green areas in 10 European capitals
Creators: name: Carpentieri, Gerardo
name: Guida, Carmen
name: Fevola, Ottavia
name: Sgambati, Sabrina
Publisher: name: TeMA - Journal of Land Use, Mobility and Environment
Year: 2020

description: The global Covid-19 pandemic has reshaped lives and activities, especially in urban areas: national and regional authorities have had to react promptly to limit the spread of the coronavirus and avoid the collapse of healthy provision systems. Urban environments, as noted in several World Health Organization reports, are fertile ground for an epidemic’s rapid transformation into a pandemic due to their high densities of people, activities, structures and networks. Cities around the world have thus rapidly reorganised to manage the coronavirus crisis. This paper focuses on the spread of the Covid-19 pandemic in European countries during the initial emergency phase and the importance of safe access to and uniform distribution of urban services. We focus on urban green areas as a means of achieving better quality of life, especially for vulnerable groups like the elderly. We selected 10 capital cities (Amsterdam, Brussels, Berlin, Copenhagen, Dublin, Lisbon, London, Madrid, Paris and Rome) to reflect the heterogeneous demographic, social and economic panoramas of European countries and cities. The outcomes of this study can support decision-makers in defining priority actions to reduce the negative impacts on the elderly in the coexistence phase of the pandemic and for future development.
description: TeMA - Journal of Land Use, Mobility and Environment, Vol 13 No 3 (2020): The city challenges and external agents. Methods, Tools and Best Practices
Synaptic efficacy during repetitive activation of excitatory inputs in primate dorsolateral prefrontal cortex.
Creators: name: González-Burgos, Guillermo
name: Krimer, Leonid S.
name: Urban, Nathan
name: Barrionuevo, Germán
name: Lewis, David A.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Neurons in the monkey dorsolateral prefrontal cortex (DLPFC) fire persistently during the delay period of working memory tasks. To determine how repetitive firing affects the efficacy of synaptic inputs to DLPFC layer 3 neurons, we examined the effects of repetitive presynaptic stimulation on the amplitude and temporal summation of EPSPs. Recordings were obtained in monkey DLPFC brain slices from regular spiking (RS) pyramidal cells and two types of interneurons, fast spiking (FS) and adapting non-pyramidal (ANP) cells. Repetitive stimulation of presynaptic axons in layer 3 caused EPSP depression in RS and FS neurons, but EPSP facilitation in ANP cells. A shorter EPSP duration produced weaker temporal summation in FS neurons compared to the other cell classes. Thus, due to the combined effects of dynamic changes in EPSP amplitude and differences in temporal summation, the effect of a presynaptic spike train differed according to the postsynaptic cell class. Similar results were obtained when recording unitary EPSPs evoked in connected pairs of presynaptic RS pyramidal cells and postsynaptic RS, FS or ANP neurons. In addition, similar differences in the efficacy of sustained inputs among cell classes were observed when delay-related firing was reproduced in vitro by stimulating inputs with the timing of spike trains recorded from the DLPFC of monkeys performing a delayed-response task. We suggest that the transition from baseline firing rates to higher frequency delay-related firing may lead to the differential activation of distinct cell populations, with corresponding significant effects on the patterns of activity in local prefrontal circuits.