cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On optimal approximability results for computing the strong metric dimension
Creators: name: DasGupta, Bhaskar
name: Mobasheri, Nasim
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computational Complexity (cs.CC)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences
subject: G.2.2; F.2.2
subject: 68Q17, 68Q25, 68R10

description: The strong metric dimension of a graph was first introduced by Sebö and Tannier (Mathematics of Operations Research, 29(2), 383-393, 2004) as an alternative to the (weak) metric dimension of graphs previously introduced independently by Slater (Proc. 6th Southeastern Conference on Combinatorics, Graph Theory, and Computing, 549-559, 1975) and by Harary and Melter (Ars Combinatoria, 2, 191-195, 1976), and has since been investigated in several research papers. However, the exact worst-case computational complexity of computing the strong metric dimension has remained open beyond being NP-complete. In this communication, we show that the problem of computing the strong metric dimension of a graph of $n$ nodes admits a polynomial-time $2$-approximation, admits a $O^\ast\big(2^{\,0.287\,n}\big)$-time exact computation algorithm, admits a $O\big(1.2738^k+n\,k\big)$-time exact computation algorithm if the strong metric dimension is at most $k$, does not admit a polynomial time $(2-\varepsilon)$-approximation algorithm assuming the unique games conjecture is true, does not admit a polynomial time $(10\sqrt{5}-21-\varepsilon)$-approximation algorithm assuming P$\neq$NP, does not admit a $O^\ast\big(2^{o(n)}\big)$-time exact computation algorithm assuming the exponential time hypothesis is true, and does not admit a $O^\ast\big(n^{o(k)}\big)$-time exact computation algorithm if the strong metric dimension is at most $k$ assuming the exponential time hypothesis is true.
description: revised version based on reviewer comments; to appear in Discrete Applied Mathematics
Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS)
Creators: name: Han, Meilan K
name: Donohue, Kathleen M
name: Hansel, Nadia N
name: Couper, David
name: Kanner, Richard E
name: Barr, R Graham
name: Rennard, Stephen
name: Kleerup, Eric
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: COPD is characterized by reduced airway lumen dimensions and fewer peripheral airways. Most studies of airway properties sample airways based upon lumen dimension or at random, which may bias comparisons given reduced airway lumen dimensions and number in COPD. We sought to compare central airway wall dimensions on computed tomography (CT) in COPD and controls using spatially matched airways, thereby avoiding selection bias of airways in the lung.
Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: Potential compensation by CIB family members
Creators: name: Gentry, Holly R.
name: DeNofrio, Jan C.
name: Temple, Brenda R.
name: Parise, Leslie V.
name: Yuan, Weiping
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Platelet aggregation requires activation of the αIIbβ3 integrin,an event regulated by the integrin cytoplasmic tails. CIB1 binds to the cytoplasmic tail of the integrin αIIb subunit. Previous overexpression and knockdown studies in murine megakaryocytes demonstrated that CIB1 inhibits integrin αIIbβ3 activation.Here we analyzed Cib1-/- mice to determine the function of CIB1 in platelets in vitro and in vivo. We found that although these mice had no overt platelet phenotype, mRNA level of CIB1 homolog CIB3 was increased in Cib1-/- megakaryocytes. In vitro binding experiments showed that recombinant CIB1, -2 and -3 bound specifically to an αIIb cytoplasmic tail peptide. Subsequent protein modeling experiments indicated that CIBs 1–3 each have a highly conserved hydrophobic binding pocket. Therefore, the potential exists for compensation for the loss of CIB1 by these CIB family members, thereby preventing pathologic thrombus formation in Cib1-/- mice.
FAIRness of Open Research Data
Creators: name: Dr Silvia Tomescu
Publisher: name: Zenodo
Year: 2023
Subjects: Open Science
FAIR Principles
FAIR Data
Metadata

description: Open science has been prioritized by the European Council for the environment of research and education. Data expression through specific languages, reusing research data, and annotation with discoverable metadata are all required components of the FAIR principles. The shift towards open data forced the development of new methods for processing data in various environments and using various technologies (description and storage standards, platforms and repositories, security issues, publishing formats, usage and citation requirements). As a stand-alone characteristic, FAIRness guarantees adherence to the principles of open access, interoperability, reuse, adding value, and encouraging new research.
Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram
Creators: name: Key, Nigel
name: Wu, Jogin
name: Machlus, Kellie
name: Koch, Gary
name: Wolberg, Alisa
name: Colby, Emily
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Elevated procoagulant levels have been correlated with increased thrombin generation in vitro and with increased venous thromboembolism (VTE) risk in epidemiological studies. hrombin generation tests are increasingly being employed as a high throughput method to provide a global measure of procoagulant activity in plasma samples. The objective of this study was to distinguish the effects of assay conditions [tissue factor (TF), thrombomodulin, platelets/lipids] and factor levels on thrombin generation parameters, and determine the conditions and parameters with the highest sensitivity and specificity for detecting elevated factor levels. Thrombin generation was measured using calibrated automated thrombography (CAT) in corn trypsin inhibitor (CTI)-treated platelet-free plasma (PFP) and plateletrich plasma (PRP). Statistical analysis was performed using logarithms of observed values with analysis of variance that accounted for experiment and treatment. he relative sensitivity of lag time (LT), time to peak (TTP), peak height and endogenous thrombin potential (ETP) to elevated factors XI, IX,VIII, X, and prothrombin was as follows: PFP initiated with 1 pM TF > PFP initiated with 5 pM TF > PRP initiated with 1 pM TF. For all conditions, inclusion of thrombomodulin prolonged the LT and decreased the peak and ETP; however, addition of thrombomodulin did not increase the ability of CAT to detect elevated levels of individual procoagulant factors. In conclusion, CAT conditions differentially affected the sensitivity of thrombin generation to elevated factor levels. Monitoring the peak height and/ or ETP following initiation of clotting in PFP with 1 pM TF was most likely to detect hypercoagulability due to increased procoagulant factor levels.
Large System Analysis of the Energy Consumption Distribution in Multi-User MIMO Systems with Mobility
Creators: name: Sanguinetti, Luca
name: Moustakas, Aris L.
name: Bjornson, Emil
name: Debbah, Merouane
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this work, we consider the downlink of a single-cell multi-user MIMO system in which the base station (BS) makes use of $N$ antennas to communicate with $K$ single-antenna user equipments (UEs). The UEs move around in the cell according to a random walk mobility model. We aim at determining the energy consumption distribution when different linear precoding techniques are used at the BS to guarantee target rates within a finite time interval $T$. The analysis is conducted in the asymptotic regime where $N$ and $K$ grow large with fixed ratio under the assumption of perfect channel state information (CSI). Both recent and standard results from large system analysis are used to provide concise formulae for the asymptotic transmit powers and beamforming vectors for all considered schemes. These results are eventually used to provide a deterministic approximation of the energy consumption and to study its fluctuations around this value in the form of a central limit theorem. Closed-form expressions for the asymptotic means and variances are given. Numerical results are used to validate the accuracy of the theoretical analysis and to make comparisons. We show how the results can be used to approximate the probability that a battery-powered BS runs out of energy and also to design the cell radius for minimizing the energy consumption per unit area. The imperfect CSI case is also briefly considered.
description: 8 figures, 2 tables, to appear on IEEE Transactions on Wireless Communications
Hypodysfibrinogenemia causing mild bleeding and thrombotic complications in a compound heterozygote of AαIVS4+1G>T mutation and Aα4841delC truncation (AαPerth)
Creators: name: Lord, Susan T.
name: Jayo, Asier
name: Green, David
name: Arnold, Erin
name: González-Manchón, Consuelo
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: 3 páginas, 1 figura -- PAGS nros. 770-772
Tissue factor and thrombosis: The clot starts here
Creators: name: Owens, A. Phillip
name: Mackman, Nigel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Thrombosis, or complications from thrombosis, currently occupies the top three positions in the cardiovascular causes of morbidity and mortality in the developed world. There are a limited number of safe and effective drugs to prevent and treat thrombosis. Animal models of thrombosis are necessary to better understand the complex components and interactions involved in the formation of a clot. Tissue factor (TF) is required for the initiation of blood coagulation and likely plays a key role in both arterial and venous thrombosis. Understanding the role of TF in thrombosis may permit the development of new antithrombotic drugs. This review will focus on the role of TF in in vivo models of thrombosis.
NuSTAR Detection Of A Cyclotron Line In The Supergiant Fast X-ray Transient IGR J17544-2619
Creators: name: Bhalerao, Varun
name: Romano, Patrizia
name: Tomsick, John
name: Natalucci, Lorenzo
name: Smith, David M.
name: Bellm, Eric
name: Boggs, Steven E.
name: Chakrabarty, Deepto
name: Christensen, Finn E.
name: Craig, William W.
name: Fuerst, Felix
name: Hailey, Charles J.
name: Harrison, Fiona A.
name: Krivonos, Roman A.
name: Lu, Ting-Ni
name: Madsen, Kristin
name: Stern, Daniel
name: Younes, George
name: Zhang, William
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present NuSTAR spectral and timing studies of the Supergiant Fast X-ray Transient (SFXT) IGR J17544-2619. The spectrum is well-described by a ~1 keV blackbody and a hard continuum component, as expected from an accreting X-ray pulsar. We detect a cyclotron line at 17 keV, confirming that the compact object in IGR J17544-2619 is indeed a neutron star. This is the first measurement of the magnetic field in a SFXT. The inferred magnetic field strength, B = (1.45 +/- 0.03) * 10^12 G * (1+z) is typical of neutron stars in X-ray binaries, and rules out a magnetar nature for the compact object. We do not find any significant pulsations in the source on time scales of 1-2000 s.
description: MNRAS Accepted. 8 pages, 4 figures, 3 tables
Low-temperature magnetic properties of the Kondo lattice model in one dimension
Creators: name: Minami, Sorato
name: Kawamura, Hikaru
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Low-temperature magnetic properties of the one-dimensional Kondo-lattice model with classical localized spins are investigated by means of a Monte Carlo simulation combined with an exact diagonalization technique. Comparative simulations are also made for the RKKY classical Heisenberg model known to be perturbatively derived in the weak-coupling limit. In addition to the previously identified antiferromagnetic, ferromagnetic and coplanar helical phases, the chiral noncoplanar phase and the collinear phases of the period-4 and 6 are newly identified, neither of which is realized in the corresponding RKKY model. The period-4 collinear phase persists even in the weak-coupling limit at the 1/4- and 3/4-fillings, invalidating the perturbative approach at these fillings.
Survey and Evaluation of Cold War Resources, New Boston Air Station, New Boston, New Hampshire
Creators: name: Wurtz, Michelle
Year: 1999
Subjects: subject: New Boston Air Force Station
valueUri: https://core.tdar.org/browse/geographic-keyword/80942/new-boston-air-force-station
subject: New Hampshire (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/704/new-hampshire-state-territory
subject: Cold War Era
valueUri: https://core.tdar.org/browse/temporal-keyword/5551/cold-war-era
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Military Structure
valueUri: https://core.tdar.org/browse/site-type/322/military-structure
subject: Non-Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/309/non-domestic-structures
subject: Cold War survey
valueUri: https://core.tdar.org/browse/other-keyword/160849/cold-war-survey
subject: Building Survey
valueUri: https://core.tdar.org/browse/other-keyword/158923/building-survey
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey

description: In compliance with Section 110 of the National Historic Preservation Act of 1966, as amended (NHPA), and with Air Force Instruction 32-7065, the 50th Space Wing of the United States Air Force has contracted with Parsons Engineering Science, Inc., to survey and evaluate Cold War properties at New Boston Air Station (NBAS), New Boston, New Hampshire. The field survey was originally conducted in November 1996, with additional field survey conducted in February 1998. Background research was carried out at the National Archives and Records Service, the Library of Congress, the National Register of Historic Places (NRHP), and local libraries. The evaluation of buildings at NBAS was carried out in accordance with the NRHP Criteria for Evaluation (36 CFR. Part 60). This survey and evaluation satisfies the identification requirements for above ground resources in compliance with the NHPA and contributes to Air Force stewardship of cultural resources.
Phase II prospective open-label trial of recombinant interleukin-11 in women with mild von Willebrand disease and refractory menorrhagia
Creators: name: Jaworski, Kristen
name: Kloos, Mark
name: Ragni, Margaret
name: Nichols, Timothy
name: Jankowitz, Rachel
name: Merricks, Elizabeth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Lack of effective treatment for menorrhagia is the greatest unmet healthcare need in women with von Willebrand disease (VWD). We conducted a single-centre phase II clinical trial to determine efficacy and safety of recombinant IL-11 (rhIL-11, Neumega®) given subcutaneously for up to seven days during six consecutive menstrual cycles each in seven women with mild VWD and menorrhagia refractory to haemostatic or hormonal agents. rhIL-11 reduced menstrual bleeding severity as measured by pictorial blood assessment chart (PBAC) ≥50% (to 0.05. Platelet VWF mRNA expression by quantitative PCR increased mean four-fold (1.0–13.5). rhIL-11 was well tolerated with grade 1 or less fluid retention, flushing, conjunctival erythema, and local bruising. In summary, rhIL-11 reduces menorrhagia safely and warrants further study.
Data and matlab code of figures of FOGA 2023 paper: https://doi.org/10.1145/3594805.3607126
Creators: name: Omeradzic, Amir
Publisher: name: Zenodo
Year: 2023

description: Data of OB23a (FOGA 2023): Convergence Properties of the (Âµ/ÂµI , Î»)-ES on the Rastrigin FunctionGenerate experimental results of OB23a.

* fig1/main_dyn.m: generates and displays R(g) and sigma*(g)-dynamics of Fig. 1* fig2/main_avg.m: generates sampled and analytic results for f(R) at N=1 and N=2* fig3/main_avg.m: generates sampled and R-aggregated results for f(R) at N=3,10,100,1000 * fig4/main_dyn_distr.m: first the dynamics is calculated for 500 trials. In the end, the distribution of y_i is evaluated at two residual distances (left and right sub-plot).* fig5/main_phi.m: two configurations used to generate Fig. 5. CONFIG 1 (const Y) evaluates the progress rate for a fixed given y (at R=7), while CONFIG 2 (const R) samples random y-values at R=7. The two plots need to be merged manually.* fig6/main_contour.m, fig6/main_dyn.m: progress landscape phi(sigma*, R) generated by main_contour.m, dynamics (two configurations for TAU) generated by main_dyn.m. In the end, plots can be merged manually.* fig7/main_contour.m: generates progress landscape and intersection points.* fig8_top/main_popsize.m: population sizing experiments under fixed Rastrigin A, ALPHA, by varying N and determining necessary MU(N) to achieve high success rate.    * The relevant MU_RANGE was determined beforehand. It was chosen small enough to cover the most interesting region of P_S~0.99 using many trials (instead of choosing large MU_RANGE with less trials due to limited resources).    * script writes **data_wsp.mat** (binary MATLAB file) to save data. Renamed to **data.mat** to avoid overwriting of final results.    * **data.mat**  was manually exported to text file **data.txt** for universal access.    * script **main_data.m** reads **data.mat** to generate results showing success rate and MU(N) scaling.* fig8_bottom/main_popsize.m: same procedure as in Fig. 8 (top).* fig9/main_popsize.m: same procedure as in Fig. 8, variation of A (fixed N, ALPHA).* fig10/main_popsize.m: same procedure as in Fig. 8, variation of ALPHA (fixed N, A).* fig11/main_contour_y.m: generates visualization (contour lines) of gain term.* fig12/main_contour.m: generates progress landscape including sigma_esc. Dynamics are generated using **main_dyn.m** (configurations 1-3 for varying TAU).* fig13/main_crit.m: main_crit.m calls **isolines_crit_point.m** to calculate the progress landscape and its critical sigma* (minimal sigma* with vanishing progress rate).The determination of sigma* is done by sampling the progress landscape using 1001x1001 values for sigma* and R, respectively.* fig14/main_dyn_sigma.m: loop over multiple sigma-values for the optimization under constant sigma.* fig15/main_dyn_sigma_PS.m: repeated evaluations of experiment in Fig 14. Success probability P_S is determined under optimization with constant sigma.
ASSOCIATION BETWEEN CARDIOVASCULAR DISEASE RISK FACTORS AND OCCURRENCE OF VENOUS THROMBOEMBOLISM: A TIME-DEPENDENT ANALYSIS
Creators: name: Rosamond, Wayne
name: Gornik, Heather
name: Lutsey, Pamela
name: Folsom, Aaron
name: Cushman, Mary
name: Midwest, HeartCare
name: Wattanakit, Keattiyoat
name: Bell, Elizabeth J.
name: Heckbert, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Apart from obesity, it remains controversial whether atherosclerosis and its cardiovascular risk disease (CVD) factors are associated with risk of venous thromboembolism (VTE). Using data from the Atherosclerosis Risk in Communities study (ARIC), we evaluated associations between CVD risk factors and incident VTE in a cohort of 15,340 participants who were free a history of VTE and/or anticoagulant use on enrolment. The CVD risk factors were updated during the follow-up period. Over a mean follow-up time of 15.5 years (237,375 person-years), 468 participants had VTE events. Adjusting for demographic variables and body mass index (BMI), current smokers were at greater risk [HR of 1.44 (95% CI: 1.12–1.86)] compared to non-smokers. There was a positive monotonic association between BMI and VTE risk. Individuals with a BMI ≥35 kg/m2 had a HR for VTE of 3.09 (95%CI: 2.26–4.23) compared to those with normal BMI (<25 kg/m2). Greater physical activity was associated with lower VTE risk in a demographic adjusted model; however, this association became non-significant following adjustment for BMI. Alcohol intake, diabetes, hypertension, high-density lipoprotein and low-density lipoprotein cholesterol, and triglycerides were not associated with VTE risk. In conclusion, among the well-established CVD risk factors, only current smoking and obesity were independently associated with VTE risk in this large cohort where risk factors were updated serially during follow-up. This finding corroborates that the pathogenesis of venous disease differs from that of atherosclerotic disease.
Flip-flopping binary black holes
Creators: name: Lousto, Carlos O.
name: Healy, James
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We study binary spinning black holes to display the long term individual spin dynamics. We perform a full numerical simulation starting at an initial proper separation of $d\approx25M$ between equal mass holes and evolve them down to merger for nearly 48 orbits, 3 precession cycles, and half of a flip-flop cycle. The simulation lasts for $t=20000M$ and displays a total change in the orientation of the spin of one of the black holes from initially aligned with the orbital angular momentum to a complete anti-alignment after half of a flip-flop cycle. We compare this evolution with an integration of the 3.5 Post-Newtonian equations of motion and spin evolution to show that this process continuously flip-flops the spin during the lifetime of the binary until merger. We also provide lower order analytic expressions for the maximum flip-flop angle and frequency. We discuss the effects this dynamics may have on spin growth in accreting binaries and on the observational consequences for galactic and supermassive binary black holes.
description: 5 pages, 5 figures. To appear in Physical Review Letters
Using entanglement against noise in quantum metrology
Creators: name: Demkowicz-Dobrzanski, Rafal
name: Maccone, Lorenzo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We analyze the role of entanglement among probes and with external ancillas in quantum metrology. In the absence of noise, it is known that unentangled sequential strategies can achieve the same Heisenberg scaling of entangled strategies and that external ancillas are useless. This changes in the presence of noise: here we prove that entangled strategies can have higher precision than unentangled ones and that the addition of passive external ancillas can also increase the precision. We analyze some specific noise models and use the results to conjecture a general hierarchy for quantum metrology strategies in the presence of noise.
description: 7 pages, 4 figures, published version
Disruption of PF4/H multimolecular complex formation with a minimally anticoagulant heparin (ODSH)
Creators: name: Wiesner, Mark R.
name: Arepally, Gowthami M.
name: Pempe, Elizabeth
name: Monroe, Dougald M.
name: Marcus, Stephen
name: Diez, Pedro M.
name: Espinasse, Benjamin
name: Joglekar, Manali V.
name: Liu, Jian
name: Qi, Rui
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Recent studies have shown that ultra-large complexes (ULCs) of platelet factor 4 (PF4) and heparin (H) play an essential role in the pathogenesis of heparin-induced thrombocytopenia (HIT), an immune-mediated disorder caused by PF4/H antibodies. Because antigenic PF4/H ULCs assemble through non-specific electrostatic interactions, we reasoned that disruption of charge-based interactions can modulate the immune response to antigen. We tested a minimally anticoagulant compound (2-O, 3-O desulfated heparin, ODSH) with preserved charge to disrupt PF4/H complex formation and immunogenicity. We show that ODSH disrupts complexes when added to pre-formed PF4/H ULCs and prevents ULC formation when incubated simultaneously with PF4 and UFH. In other studies, we show that excess ODSH reduces HIT antibody (Ab) binding in immunoassays and that PF4/ODSH complexes do not cross-react with HIT Abs. When ODSH and unfractionated heparin (UFH) are mixed at equimolar concentrations, we show that there is a negligible effect on amount of protamine required for heparin neutralisation and reduced immunogenicity of PF4/UFH in the presence of ODSH. Taken together, these studies suggest that ODSH can be used concurrently with UFH to disrupt PF4/H charge interactions and provides a novel strategy to reduce antibody mediated complications in HIT.
Extrapolation and unitarity bounds for the $B \to π$ form factor
Creators: name: Imsong, I. Sentitemsu
name: Khodjamirian, Alexander
name: Mannel, Thomas
name: van Dyk, Danny
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We address the problem of extrapolating the vector form factor $f_{Bπ}^+$, which is relevant to $B\to π\ell ν_\ell$ decays, from the region of small to the region of large momentum transfer. As input, we use the QCD light-cone sum rule at small momentum transfer. We carry out a comprehensive Bayesian uncertainty analysis and obtain correlated uncertainties for the normalization and shape parameters of the form factor. The $z$-series parametrization for $f_{Bπ}^+$ is employed to extrapolate our results to large momentum transfer, and to compare with the lattice QCD results. To test the validity of our extrapolation we use the upper and lower bounds from the unitarity and positivity of the two-point correlator of heavy-light quark currents. This correlator is updated by including the NNLO perturbative term and the NLO correction to the quark condensate contribution. We demonstrate that an additional input including the form factor, its first and second derivative calculated at one value of momentum transfer from the light-cone sum rules, considerably improves the bounds. This only holds when the correlations between the form factor parameters are taken into account. We further combine our results with the latest experimental measurements of $B\to π\ell ν_\ell$ by the BaBar and Belle collaborations, and obtain $|V_{ub}|= (3.32^{+0.26}_{-0.22}) \cdot 10^{-3}$ from a Bayesian analysis.
description: 26 pages, 4 figures; v2: as published (reference and zoomed plot added, conclusions and numerics unchanged)
Collective Modes in a Superfluid Neutron Gas within the Quasiparticle Random-Phase Approximation
Creators: name: Martin, Noël
name: Urban, Michael
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study collective excitations in a superfluid neutron gas at zero temperature within the quasiparticle random phase approximation. The particle-hole residual interaction is obtained from a Skyrme functional, while a separable interaction is used in the pairing channel which gives a realistic density dependence of the pairing gap. In accordance with the Goldstone theorem, we find an ungapped collective mode (analogous to the Bogoliubov-Anderson mode). At low momentum, its dispersion relation is approximately linear and its slope coincides with the hydrodynamic speed of sound calculated with the Skyrme equation of state. The response functions are compared with those obtained within the Landau approximation. We also compute the contribution of the collective mode to the specific heat of the neutron gas, which is relevant for the thermodynamic properties of the inner crust of neutron stars.
description: 12 pages
A Hamiltonian approach to implicit systems, generalized solutions and applications in optimization
Creators: name: Tiba, Dan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 26B10, 34A12, 49K21, 49M37

description: We introduce a constructive method that provides the local solution of general implicit systems in arbitrary dimension via Hamiltonian type equations. A variant of this approach constructs parametrizations of the manifold, extending the usual implicit functions solution. We also discuss the critical case of the implicit functions theorem, define the notion of generalized solution and prove existence and properties. Examples are also indicated. The applications concern necessary conditions and algorithms in nonconvex optimization problems and their perturbations.
title: Entnazifizierung im Lager 373 Camp Wolfsberg
Creators: name: Markus, Christina
Year: 2022

description: Der im Dokumentationsarchiv des Österreichischen Widerstandes (DÖW) befindliche Briefbestand des Paares Maria Praßl und Hans Raunikar wurde in dieser Arbeit erstmals wissenschaftlich aufgearbeitet. Die beiden Nationalsozialisten Raunikar und Praßl lernten sich 1946 im Lager 373 Camp Wolfsberg in Kärnten auf schriftlichem Weg kennen. Aus anfänglichen vorsichtigen Annäherungen wurde im Laufe der Zeit eine Liebesbeziehung, die auch außerhalb des Camps von Bestand war und zu einer Ehe führte. Die Arbeit geht den Fragen nach, ob eine Entnazifizierung stattfand, ob sich die Einstellung änderte und wie der Camp-Alltag ausschaute. Von besonderer Bedeutung für diese Arbeit sind ihre schriftlichen Ausführungen zum Alltagsleben im Camp sowie ihre nach wie vor bestehende nationalsozialistische Auffassung, die in ihren verwendeten Begrifflichkeiten zu erkennen ist und die sich weder im Camp noch im späteren Verlauf ihres Lebens änderte. Um eine bessere Vorstellung ihres Lebens und der Gründe für ihr Handeln zu bekommen, wird auf ihre Biographien bis zur Internierung 1945 eingegangen. Besonders von Interesse sind die Ausführungen und Ansichten der Familie Raunikar zu diesem Thema im angeschlossenen Interview.
description: The inventory of letters from the couple Maria Praßl and Hans Raunikar, which is in the Documentation Centre of Austrian Resistance (DÖW), was scientifically processed for the first time in this work. The two National Socialists, Raunikar and Praßl, got to know each other in writing in 1946 in Camp 373, Wolfsberg Camp in Carinthia. Over time, the initial cautious approaches turned into a love affair that also lasted outside the camp and led to a marriage. The work explores the questions of whether denazification took place, whether attitudes changed and what everyday camp life looked like. Of particular importance for this work are their written statements on everyday life in the camp and their still existing National Socialist point of view, which can be seen in the terminology used in their letters and which changed neither in the camp nor later in their life. In order to get a better idea of their lives and the reasons for their actions, their biographies up until their internment in 1945 are discussed. The comments and views of the Raunikar family on this topic in the interview that follows are of particular interest.
title: Juraj Jánošík vs. Alžbeta Báthoryová
Creators: name: Ludl, Katharina
Year: 2022

description: Das Ziel dieser Masterarbeit war eine genaue Analyse und der Vergleich der beiden Werke Ján Bottos. Dazu erfolgte zunächst eine Einordnung des Autors in die Epoche der Romantik und die Relevanz der politischen und historischen Einflüsse auf den Dichter und sein Œuvre. Dabei wird besonders auf die literarische Prägung des jungen Botto hingewiesen, unter ande-rem am Lyzeum Levoča oder durch neue ästhetische Konzeptionen des Štúrschen Dichter-kreises, dessen jüngstes Mitglied er war. Diese beiden Schulen und sein Studium in Budapest bestärkten seine literarischen und nationalen Interessen, siehe dazu auch den regen Briefwechsel zwischen Ján Botto und seinem lebenslangen Freund Pavol Dobšinský. Botto beschäftigte sich unter anderem mit der zeitgenössischen deutschen, russischen, polnischen und auch englischen Literatur seiner Zeit. Er ließ sich von diesen Idealen, Motiven und formalen Realisierungen inspirieren und passte sie an heimische bzw. slowakische Formen an. Zusätzlich konzentrierte sich sein Fokus auch auf die Folklore und die Quellen des Volksschriftums. Botto sah in Märchen und Sagen die Urform der slowakischen Literatur. Nach dem enttäuschenden Ausgang der Revolution 1848/49 und der darauf folgenden Ära Bach veränderte sich gezwungenermaßen Bottos Blickwinkel und dichterischer Ausdruck. Daraus resultierte, dass die Allegorie eine grundlegende Position in seiner Dichtung einnahm. Diese war auch formal durch den literarischen Synkretismus geprägt. Botto verband die Desillusion der Wirklichkeit mit der imaginären und märchenhaften Traumwelt. Dazu wählte er in Smrť Jánošíkova die romantische Figur des Räubers als Helden und das Motiv des schlafenden Volkes und verwunschenen Landes. Interessant ist dabei, dass Botto sich nicht an der historischen Figur orientierte, sondern ein neues Ideal des Helden anhand der tradierten Gestalt aus der Folklore erschuf. Botto adaptierte seine Dichtung mehrmals kritisch und erschuf so verschiedene Versionen, angepasst an die jeweilige gesellschaftliche Situation. An dieser Stelle wird auch damit zusammenhängend auf die Transformation der Erinnerungsfigur des Räuberbildes und die zahlreichen Rezeptionen der Jánošík-Thematik hingewiesen sowie auf die Mythenbildung der Alžbeta Báthoryová im nationalen Bewusstseinsprozess.
Multivariate orthogonal polynomial and integrable systems
Creators: name: Ariznabarreta, Gerardo
name: Mañas, Manuel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Mathematical Physics (math-ph)
subject: Rings and Algebras (math.RA)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 15A23, 33C45, 37K10, 37L60, 42C05, 46L55

description: Multivariate orthogonal polynomials in $D$ real dimensions are considered from the perspective of the Cholesky factorization of a moment matrix. The approach allows for the construction of corresponding multivariate orthogonal polynomials, associated second kind functions, Jacobi type matrices and associated three term relations and also Christoffel-Darboux formulæ. The multivariate orthogonal polynomials, its second kind functions and the corresponding Christoffel-Darboux kernels are shown to be quasi-determinants --as well as Schur complements-- of bordered truncations of the moment matrix; quasi-tau functions are introduced. It is proven that the second kind functions are multivariate Cauchy transforms of the multivariate orthogonal polynomials. Discrete and continuous deformations of the measure lead to Toda type integrable hierarchy, being the corresponding flows described through Lax and Zakharov-Shabat equations; bilinear equations are found. Varying size matrix nonlinear partial difference and differential equations of the 2D Toda lattice type are shown to be solved by matrix coefficients of the multivariate orthogonal polynomials. The discrete flows lead to expressions for the multivariate orthogonal polynomials and its second kind functions in terms of shifted quasi-tau matrices, which generalize to the multidimensional realm those that relate the Baker and adjoint Baker functions with ratios of Miwa shifted $τ$-functions in the 1D scenario. In this context, the multivariate extension of the elementary Darboux transformation is given in terms of quasi-determinants of matrices built up by the evaluation, at a poised set of nodes lying in an appropriate hyperplane in $\mathbb R^D$, of the multivariate orthogonal polynomials. The multivariate Christoffel formula for the iteration of $m$ elementary Darboux transformations is given as a quasi-determinant.
description: In this third version we correct a typo
Hersiliola versicolor
Creators: name: Marusik, Yuri
name: Fet, Victor
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Hersiliidae
Hersiliola
Hersiliola versicolor

description: Hersiliola versicolor (Blackwall, 1865) Fig. 7.1 Hersilia v. Blackwall, 1865: 81 (D ♀). H. v.: Simon 1893: 445. H. v.: Foord and Dippenaar-Schoeman 2005: 261, f. 4A-D (♀). Material examined: A slide of an epigyne (SMF, from the H. Wiehle collection) from “Kapeverde, Maio ” [= Cape Verde Islands, Maio Island]. Identified as H. simoni. Diagnosis. H. versicolor is similar to H. simoni, but differs from it by the shape of the median plate of the epigyne, which is much higher and has a wider septum. Description. Redescribed by Foord and Dippenaar-Schoeman (2005). Comments. This species is known from females only. The shape of the median plate illustrated by Foord and Dippenaar-Schoeman (2005: fig. 4A) appears to be misinterpreted, judging from the figure of the vulva, and from the specimen (a slide of the epigyne) examined by us. Black dots on their fig. 4A and on our Fig. 7.1 seem to correspond to accessory glands. On the slide, glands seem to be displaced due to pressure from the cover glass. Distribution. Known only from the Cape Verde Islands.
description: Published as part of Marusik, Yuri & Fet, Victor, 2009, A survey of East Palaearctic Hersiliola Thorell, 1870 (Araneae, Hersiliidae), with a description of three new genera, pp. 75-114 in ZooKeys 16 (16) on page 83, DOI: 10.3897/zookeys.16.229, http://zenodo.org/record/576478
description: {"references": ["Blackwall J (1865) Descriptions of recently discovered spiders collected in the Cape de Verde Islands by John Gray, Esq. Annals and Magazine of Natural History (3) 16: 80 - 101.", "Simon E (1893) Histoire naturelle das araignees. Paris 1: 257 - 488.", "Foord SH, Dippenaar-Schoeman AS (2005) A revision of the Afrotropical species of Hersiliola Thorell and Tama Simon with the description of a new genus Tyrotama (Araneae: Hersiliidae). African Entomology 13 (2): 255 - 279."]}
A MATTER OF STYLE.HOW MAP THINKING AND BIO-ONTOLOGIES SHAPE CONTEMPORARY MOLECULAR RESEARCH
Creators: name: BOEM, FEDERICO
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: ABSTRACT The aim of this thesis is to provide an epistemic analysis of the transformations occurring in contemporary biological research by considering the relation between molecular biology and computational biology. In particular, I will focus on bio-ontologies, as the tool which incarnates at best the new face of biomedical research. Such a choice is not arbitrary. By appealing to the notion of style of reasoning and way of knowing, I will show that bio-ontologies exemplify the rise and success of map thinking as the signature of a new way of doing molecular biology, while the theoretical tenets, established more than 30 years ago, still maintain their epistemic prominence. This is neither to say that experimentalism will disappear from science, nor that the experiments power will be diminished but rather that experiments will have a new role in the architecture of scientific efforts, precisely because of the increasing importance of classificatory approaches. Therefore, such a transition within biomedical research is indeed radical and profound but it does not involve paradigm shifts but rather a change in the practice. In this sense, it is a matter of style.
L�ECOGRAFIA IN MEDICINA RESPIRATORIA: REALT� ITALIANA, UTILIZZO CLINICO E NUOVE INDICAZIONI
Creators: name: SFERRAZZA PAPA, GIUSEPPE FRANCESCO
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: ULTRASOUND IN RESPIRATORY MEDICINE: AN ITALIAN EXPERIENCE AND CURRENT AND NOVEL CLINICAL APPLICATIONS Over the last couple of decades, thoracic ultrasound witnessed a growing attention especially in the emergency medicine/intensive care units and respiratory medicine. This is presumably due to its point-of-care ability to detect and monitor a wide spectrum of lung and pleural diseases at relatively low costs and with no ionizing radiation. On this ground, dr. Giuseppe Francesco Sferrazza Papa?s PhD program was conceived to expand current knowledge on clinical applications of ultrasound in respiratory medicine that are reported in details in the present thesis. As a first step of the project, a two-year longitudinal study in a hospital setting and a cross-sectional survey have been conducted with the aim to examine the practical interest and application of ultrasound within the pulmonary medical Italian community. Both studies showed a widespread interest and use in Italy, a fact that provides a strong rationale to further explore the potentials of ultrasound in this field. Subsequently, four clinical studies were performed with the aim to best examine the accuracy of ultrasound to diagnose community-acquired pneumonia in children, to clarify the clinical meaning of the ultrasound interstitial pattern, to evaluate the effects of adding ultrasound to the Wells score for suspected pulmonary embolism, and finally to check the accuracy of the technique in detecting the pathogenesis of pleuritic thoracic pain. All these studies achieved the expected targets, thus providing solid evidence that ultrasound is important in clinical practice and has a large potential that respiratory medicine has yet to exploit.
Herbivory and nutrients shape grassland soil seed banks
Creators: name: Eskelinen, Anu
name: Jessen, Maria-Theresa
name: Bahamonde, Hector A.
name: Bakker, Jonathan D.
name: Borer, Elizabeth T.
name: Caldeira, Maria C.
name: Harpole, Stan
name: Jia, Meiyu
name: Lannes, Luciola S.
name: Nogueira, Carla
name: Venterink, Harry Gerhardus Maria Olde
name: Peri, Pablo Luis
name: Porath-Krause, Anita J.
name: Seabloom, Eric W.
name: Schroeder, Katie
name: Tognetti, Pedro M.
name: Yasui, Simone-Louise E.
name: Virtanen, Risto
name: Sullivan, Lauren L.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 580

description: Anthropogenic nutrient enrichment and shifts in herbivory can lead to dramatic changes in the composition and diversity of aboveground plant communities. In turn, this can alter seed banks in the soil, which are cryptic reservoirs of plant diversity. Here, we use data from seven Nutrient Network grassland sites on four continents, encompassing a range of climatic and environmental conditions, to test the joint effects of fertilization and aboveground mammalian herbivory on seed banks and on the similarity between aboveground plant communities and seed banks. We find that fertilization decreases plant species richness and diversity in seed banks, and homogenizes composition between aboveground and seed bank communities. Fertilization increases seed bank abundance especially in the presence of herbivores, while this effect is smaller in the absence of herbivores. Our findings highlight that nutrient enrichment can weaken a diversity maintaining mechanism in grasslands, and that herbivory needs to be considered when assessing nutrient enrichment effects on seed bank abundance.
Dysregulated coagulation associated with hypofibrinogenaemia and plasma hypercoagulability: Implications for identifying coagulopathic mechanisms in humans
Creators: name: Campbell, Robert A.
name: Mackman, Nigel
name: Wolberg, Alisa S.
name: Ma, Alice D.
name: Lin, Feng-Chang
name: Marchi, Rita
name: McGary, Colleen S.
name: Pawlinski, Rafal
name: Di Paola, Jorge
name: Walton, Bethany L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Identifying coagulation abnormalities in patients with combined bleeding and thrombosis history is clinically challenging. Our goal was to probe the complexity of dysregulated coagulation in humans by characterizing pathophysiologic mechanisms in a patient with both bleeding and thrombosis. The patient is a 56-year-old female with a history of haematomas, poor wound healing, and thrombosis (retinal artery occlusion and transient cerebral ischaemia). She had a normal activated partial thromboplastin time, prolonged thrombin and reptilase times, and decreased functional and antigenic fibrinogen levels, and was initially diagnosed with hypodysfibrinogenaemia. This diagnosis was supported by DNA analysis revealing a novel FGB mutation (c.656A>G) predicting a Q189R mutation in the mature chain that was present in the heterozygote state. However, turbidity analysis showed that purified fibrinogen polymerisation and degradation were indistinguishable from normal, and Bβ chain subpopulations appeared normal by two-dimensional difference in-gel electrophoresis, indicating the mutated chain was not secreted. Interestingly, plasma thrombin generation testing revealed the patient’s thrombin generation was higher than normal and could be attributed to elevated levels of factor VIII (FVIII, 163–225%). Accordingly, in an arterial injury model, hypofibrinogenaemic mice (Fgn+/−) infused with factor VIII demonstrated significantly shorter vessel occlusion times than saline-infused Fgn+/− mice. Together, these data associate the complex bleeding and thrombotic presentation with combined hypofibrinogenaemia plus plasma hypercoagulability. These findings suggest previous cases in which fibrinogen abnormalities have been associated with thrombosis may also be complicated by co-existing plasma hypercoagulability and illustrate the importance of “global” coagulation testing in patients with compound presentations.
Bose-Einstein condensate of metastable helium for quantum correlation experiments
Creators: name: Keller, Michael
name: Kotyrba, Mateusz
name: Leupold, Florian
name: Singh, Mandip
name: Ebner, Maximilian
name: Zeilinger, Anton
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We report on the realization of Bose-Einstein condensation of metastable helium-4. After exciting helium to its metastable state in a novel pulse-tube cryostat source, the atomic beam is collimated and slowed. We then trap several 10^8 atoms in a magneto-optical trap. For subsequent evaporative cooling, the atoms are transferred into a magnetic trap. Degeneracy is achieved with typically a few 10^6 atoms. For detection of atomic correlations with high resolution, an ultrafast delay-line detector has been installed. Consisting of four quadrants with independent readout electronics that allow for true simultaneous detection of atoms, the detector is especially suited for quantum correlation experiments that require the detection of correlated subsystems. We expect our setup to allow for the direct demonstration of momentum entanglement in a scenario equivalent to the Einstein-Podolsky-Rosen gedanken experiment. This will pave the way to matter-wave experiments exploiting the peculiarities of quantum correlations.
description: 10 pages, 12 figures