Metadata record for the article: Impact of estrogen receptor levels on outcome in non-metastatic triple negative breast cancer patients treated with neoadjuvant/adjuvant chemotherapy
Creators: name: Dieci, Maria Vittoria
name: Griguolo, Gaia
name: Bottosso, Michele
name: Tsvetkova, Vassilena
name: Giorgi, Carlo Alberto
name: Vernaci, Grazia
name: Michieletto, Silvia
name: Angelini, Silvia
name: Marchet, Alberto
name: Tasca, Giulia
name: Genovesi, Elisa
name: Cumerlato, Enrico
name: Mele, Marcello Lo
name: Conte, PierFranco
name: Guarneri, Valentina
Publisher: name: figshare
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: FOS: Clinical medicine
subject: Biomarkers
subject: Diseases

description: <b>Summary</b><br> This metadata record provides details of the data supporting the claims of the related article: “Impact of estrogen receptor levels on outcome in non-metastatic triple negative breast cancer patients treated with neoadjuvant/adjuvant chemotherapy”. The related study evaluated clinical outcomes according to estrogen receptor (ER) levels in a monoinstitutional cohort of non-metastatic triple negative breast cancer (BC) patients undergoing (neo)adjuvant chemotherapy. Type of data: clinical data; analysis from retrospective data Subject of data: <i>Homo sapiens</i> Population characteristics and recruitment: All consecutive patients diagnosed with stage I-III BC with ER expression &lt;10% by IHC and HER2-negative according to current ASCO/CAP recommendations treated with neoadjuvant and/or adjuvant chemotherapy at Istituto Oncologico Veneto of Padova between January 2000 and April 2019 were included <b>Data access</b> The data underlying the claims of the related study (demographic, clinicopathologic and treatment data retrospectively collected from medical charts; ER expression on pretreatment core biopsy specimens for patients treated with neoadjuvant chemotherapy; ER expression on surgical specimens for patients receiving adjuvant chemotherapy) are contained in the file ‘TNBC_ERlow_Padova.txt’. This file is not publicly available for the following reason: data contain information that could compromise research participant privacy and informed consent to share participant-level data was not obtained prior to or during data collection. However, the data can be made available upon request to the corresponding author. <b>Corresponding author(s) for this study</b> Prof. Valentina Guarneri, MD PhD. Department of Surgery, Oncology and Gastroenterology, University of Padova, Division of Oncology 2, Istituto Oncologico Veneto IRCCS, Via Gattamelata 64, 35128 Padova, Italy. Telephone: +39 0498215931. Fax: +39 0498215932. E-mail: valentina.guarneri@unipd.it<br> <br> <b></b> <b>Study approval </b> The study was approved by the ethics committee of Istituto Oncologico Veneto and all relevant ethical regulations have been complied with. Informed consent was obtained from all participants.