cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2012
Subjects: miR-29b
microRNA
multiple myeloma
DNA methyltransferases
DNMT

description: Aberrant DNA methylation plays a relevant role in multiple myeloma (MM) pathogenesis. MicroRNAs (miRNAs) are a class of small non-coding RNAs that recently emerged as master regulator of gene expression by targeting protein-coding mRNAs. However, miRNAs involvement in the regulation of the epigenetic machinery and their potential use as therapeutics in MM remain to be investigated. Here, we provide evidence that the expression of de novo DNA methyltransferases (DNMTs) is deregulated in MM cells.Moreover, we show that miR-29b targets DNMT3A and DNMT3B mRNAs and reduces global DNA methylation in MM cells. In vitro transfection of MM cells with synthetic miR-29b mimics significantly impairs cell cycle progression and also potentiates the growth-inhibitory effects induced by the demethylating agent 5-azacitidine. Most importantly, in vivo intratumor or systemic delivery of synthetic miR-29b mimics, in two clinically relevant murine models of human MM, including the SCID-synth-hu system, induces significant anti-tumor effects. All together, our findings demonstrate that aberrant DNMTs expressionis efficiently modulated by tumor suppressive synthetic miR-29b mimics, indicating that methyloma modulation is a novel matter of investigation in miRNA-based therapy of MM. copy; Amodio et al.
Physical properties of double-mode RR Lyrae stars based on pulsation and evolution models
Creators: name: Dekany, Istvan
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We determine the fundamental stellar parameters of altogether 20 double-mode RR Lyrae (RRd) stars from the Galactic Field and the Large Magellanic Cloud, following our approach employed on the field RRd star BS Comae. The stars were selected to cover wide ranges of periods and period ratios, implying diverse stellar parameters. From the possible observed quantities we use only the periods and determine stellar parameter combinations that satisfy both current helium-burning evolutionary models and grids of linear non-adiabatic purely radiative pulsational models. Thus, the periods of an object determine a sequence of solutions for its mass, luminosity, effective temperature and metallicity, parametrized by the time elapsed from the zero age horizontal branch. The derived sets of solutions yield various important theoretical relations between the physical parameters of the stars which are, in the case of some parameter combinations, nearly independent of the age. We get very tight simple linear relations between log(P0) and log(R), log(rho), log(g) and the Wesenheit index W(B-V). This latter period-luminosity-color relation is in good agreement with the one derived on empirical basis and calibrated by Baade-Wesselink results.
description: To be published by AIP, in the Proceedings of the 19th Stellar Pulsation Conference of the 'Los Alamos Series', held in Santa Fe, NM, from May 31 to June 5, 2009
ANIMA D3.10 - Studies on Virtual and Auralisation tools
Creators: name: Dedieu, Romain
name: Lavandier, Catherine
Publisher: name: Zenodo
Year: 2021

description: This document gives account for the laboratory and in-situ experiments conducted in order to probe the relevance of an auralization and visualization tool for providing credible communication and engagement with communities around airports. Lab studies are dedicated to assess the validity of the Virtual Community Noise Simulator (VCNS) developed by the Royal Netherlands Aerospace Centre (NLR). Then,in-situ experiment tried to evaluate the advantage of the use of the VCNS compared to a classical communication campaign about a real change in approach procedure. The experiment was organized by Cergy University in Beauchamp (Val d’Oise, France, 25km far from Roissy Charles de Gaulle) where a continuous descent approach should be applied to all flyovers in 2023.
Surveying the Giant HII Regions of the Milky Way with SOFIA: III. W49A
Creators: name: De Buizer, James M.
name: Lim, Wanggi
name: Liu, Mengyao
name: Karnath, Nicole
name: Radomski, James
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present our third set of results from our mid-infrared imaging survey of Milky Way Giant HII (GHII) regions with our detailed analysis of W49A, one of the most distant, yet most luminous, GHII regions in the Galaxy. We used the FORCAST instrument on the Stratospheric Observatory For Infrared Astronomy (SOFIA) to obtain 20 and 37$μ$m images of the entire ~5.0' x 3.5' infrared-emitting area of W49A at a spatial resolution of ~3". Utilizing these SOFIA data in conjunction with previous multi-wavelength observations from the near-infrared to radio, including Spitzer-IRAC and Herschel-PACS archival data, we investigate the physical nature of individual infrared sources and sub-components within W49A. For individual compact sources we used the multi-wavelength photometry data to construct spectral energy distributions (SEDs) and fit them with massive young stellar object (MYSO) SED models, and find 22 sources that are likely to be MYSOs. Ten new sources are identified for the first time in this work. Even at 37$μ$m we are unable to detect infrared emission from the sources on the western side of the extremely extinguished ring of compact radio emission sources known as the Welch Ring. Utilizing multi-wavelength data, we derived luminosity-to-mass ratio and virial parameters of the extended radio sub-regions of W49A to estimate their relative ages and find that overall the sub-components of W49A have a very small spread in evolutionary state compared to our previously studied GHII regions.
description: 35 pages, 15 figures, 10 tables, accepted for publication in ApJ
Subsystem Trace-Distances of Two Random States
Creators: name: de Miranda, Joaquim Telles
name: Micklitz, Tobias
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study two-state discrimination in chaotic quantum systems. Assuming that one of two $N$-qubit pure states has been randomly selected, the probability to correctly identify the selected state from an optimally chosen experiment involving a subset of $N-N_B$ qubits is given by the trace-distance of the states, with $N_B$ qubits partially traced out. In the thermodynamic limit $N\to\infty$, the average subsystem trace-distance for random pure states makes a sharp, first order transition from unity to zero at $f=1/2$, as the fraction $f=N_B/N$ of unmeasured qubits is increased. We analytically calculate the corresponding crossover for finite numbers $N$ of qubits, study how it is affected by the presence of local conservation laws, and test our predictions against exact diagonalization of models for many-body chaos.
description: 9 pages, 4 figures, published version
First-principles calculation of the electronic and optical properties of Gd$_{2}$FeCrO$_{6}$ double perovskite: Effect of Hubbard U parameter
Creators: name: Das, Subrata
name: Bhuyan, M. D. I.
name: Basith, M. A.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We have synthesized Gd$_{2}$FeCrO$_{6}$ (GFCO) double perovskite which is crystallized in a monoclinic structure with P2$_{1}/$n space group. The UV-visible and photoluminescence spectroscopic analyses confirmed its direct bandgap semiconducting nature. Employing experimentally obtained structural parameters in first-principles calculation, we report the spin-polarized electronic band structure, charge carrier effective mass, density of states, electronic charge density distribution and optical absorption property of the GFCO double perovskite. The effects of on-site d-d Coulomb interaction energy (U$_{eff}$) on the electronic and optical properties were investigated by applying a range of Hubbard U$_{eff}$ parameters from 0 to 6 eV to the Fe-3d and Cr-3d orbitals within the generalized gradient approximation (GGA) and GGA+U methods. When we applied U$_{eff}$ in the range of 1 to 5 eV, both the up-spin and down-spin band structures were observed to be direct. The charge carrier effective masses were also found to enhance gradually from U$_{eff} =$ 1 eV to 5 eV, but, these values were anomalous for U$_{eff} =$ 0 and 6 eV. These results suggest that U$_{eff}$ should be limited within the range of 1 to 5 eV to calculate the structural, electronic and optical properties of GFCO double perovskite. We observed that considering U$_{eff} =$ 3 eV, the theoretically calculated optical band gap 1.99 eV matched well with the experimentally obtained value 2.0 eV. The outcomes of our finding imply that the U$_{eff}$ value of 3 eV most accurately localized the Fe-3d and Cr-3d orbitals of GFCO keeping the effect of self-interaction error from the other orbitals almost negligible. Therefore, we may recommend U$_{eff} =$ 3 eV for first-principles calculation of the electronic and optical properties of GFCO double perovskite that might have potential in photocatalytic and related solar energy applications.
Vacuum Decay and Euclidean Lattice Monte Carlo
Creators: name: Shen, Jiayu
name: Draper, Patrick
name: El-Khadra, Aida X.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The decay rate of a metastable vacuum is usually calculated using a semiclassical approximation to the Euclidean path integral. The extension to a complete Euclidean lattice Monte Carlo computation, however, is hampered by analytic continuations that are ill-suited to numerical treatment, and the nonequilibrium nature of a metastable state. In this paper we develop a new methodology to compute vacuum decay rates from Monte Carlo simulations of Euclidean lattice theories. To test the new method, we consider simple quantum mechanical systems systems with metastable vacua. This work can be extended to Euclidean field theories, which we discuss in the Conclusions.
description: 33 pages, 10 figures
Concurrent word generation and motor performance: further evidence for language-motor interaction.
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2012
Subjects: Adolescent
Adult
Brain
Female
Humans
Language
Male
Memory
Motor Activity
Psychomotor Performance
Verbal Behavior
Young Adult

description: Embodied/modality-specific theories of semantic memory propose that sensorimotor representations play an important role in perception and action. A large body of evidence supports the notion that concepts involving human motor action (i.e., semantic-motor representations) are processed in both language and motor regions of the brain. However, most studies have focused on perceptual tasks, leaving unanswered questions about language-motor interaction during production tasks. Thus, we investigated the effects of shared semantic-motor representations on concurrent language and motor production tasks in healthy young adults, manipulating the semantic task (motor-related vs. nonmotor-related words) and the motor task (i.e., standing still and finger-tapping). In Experiment 1 (n = 20), we demonstrated that motor-related word generation was sufficient to affect postural control. In Experiment 2 (n = 40), we demonstrated that motor-related word generation was sufficient to facilitate word generation and finger tapping. We conclude that engaging semantic-motor representations can have a reciprocal influence on motor and language production. Our study provides additional support for functional language-motor interaction, as well as embodied/modality-specific theories.
Strumenti e metodi per lo sviluppo prodotto di lenti oftalmiche
Creators: name: Savio, Gianpaolo <1978>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2008
Subjects: ING-IND/15 Disegno e metodi dell'ingegneria industriale

description: The recent introduction of free form NC machining in the ophthalmic field involved a
full review of the former product development process both from the design and the
manufacturing viewpoint.
Aim of the present work is to investigate and to set up innovative methods and tools
supporting the product development, particularly for lenses characterized by free form
geometry, as e.g. progressive lenses.
In the design stage, the research addressed geometric modeling of complex lens shapes
and relevant analysis tools for the optical-geometrical characterization of the produced
models. In the manufacturing stage, the main interest was focused on the set-up of the
fabrication process, particularly on the NC machining process for which an integration CADCAM
software was developed for the generation and the simulation of the machining cycle.
The methodologies and tools made available by the present work are currently used in
the development of new complex geometry product typologies as, e.g. progressive lenses.
Optical dipole orientation of interlayer excitons in MoSe$_{2}$-WSe$_{2}$ heterostacks
Creators: name: Sigl, Lukas
name: Troue, Mirco
name: Katzer, Manuel
name: Selig, Malte
name: Sigger, Florian
name: Kiemle, Jonas
name: Brotons-Gisbert, Mauro
name: Watanabe, Kenji
name: Taniguchi, Takashi
name: Gerardot, Brian D.
name: Knorr, Andreas
name: Wurstbauer, Ursula
name: Holleitner, Alexander W.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We report on the far-field photoluminescence intensity distribution of interlayer excitons in MoSe$_{2}$-WSe$_{2}$ heterostacks as measured by back focal plane imaging in the temperature range between 1.7 K and 20 K. By comparing the data with an analytical model describing the dipolar emission pattern in a dielectric environment, we are able to obtain the relative contributions of the in- and out-of-plane transition dipole moments associated to the interlayer exciton photon emission. We determine the transition dipole moments for all observed interlayer exciton transitions to be (99 $\pm$ 1)% in-plane for R- and H-type stacking, independent of the excitation power and therefore the density of the exciton ensemble in the experimentally examined range. Finally, we discuss the limitations of the presented measurement technique to observe correlation effects in exciton ensembles.
An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2012
Subjects: Computer Simulation
Ion Channel Gating
Ion Channels
Kv1.2 Potassium Channel
Models, Molecular
Molecular Dynamics Simulation
Potassium Channels, Voltage-Gated
Protein Conformation
Voltage-Gated Sodium Channels

description: Developing an understanding of the mechanism of voltage-gated ion channels in molecular terms requires knowledge of the structure of the active and resting conformations. Although the active-state conformation is known from x-ray structures, an atomic resolution structure of a voltage-dependent ion channel in the resting state is not currently available. This has motivated various efforts at using computational modeling methods and molecular dynamics (MD) simulations to provide the missing information. A comparison of recent computational results reveals an emerging consensus on voltage-dependent gating from computational modeling and MD simulations. This progress is highlighted in the broad context of preexisting work about voltage-gated channels. © 2012 Vargas et al.
The principle of compensation in relation to public interference in the real property market : an interface of law and economics
Creators: name: Heung, Raymond
Publisher: name: University of British Columbia
Year: 2010

description: The objective of this thesis is to examine the principle of compensation in relation to public interferences in the real property market. Public activities in the real property market frequently have the effects of incurring losses to be suffered by some individuals in society and gains to be enjoyed by others. One crucial problem is how we should draw the line between compensable losses and non-compensable losses. In-order to determine the criteria of compensability, we have resorted to economic principles as well as legal rules. Economic principles are relevant because the losses (caused by public activities) that we are interested in are economic losses. Legal rules are also relevant because courts have often been left with the responsibility of determining fair compensation. As far as legal rules are concerned, we recognize three legal rules that have been developed from judicial decisions and legal commentary, and have been deemed to be critical in determining the criteria of compensability. We evaluate these three rules against the economic principles of allocative efficiency and the principles of justice developed by John Rawls, and we have come to the conclusion that these three rules have inherent weaknesses in determining how we should draw the line between compensable and non-compensable losses. However, these three legal rules have considerable influence on judicial decisions with respect to the provision of compensation caused by the following three types of public interferences, namely, compulsory acquisition of land, injurious affection on land, and planning restrictions of land use. Consequently, the provision of compensation under each of the above three occassions for compensation have frequently been unsatisfactory and inadequate. We have also examined recent legislative reforms in Canada, and we have noted certain welcoming changes in statutory law and have also pointed out some other areas where further reforms are required.
Heating up Peccei-Quinn scale
Creators: name: Ramazanov, Sabir
name: Samanta, Rome
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss production of QCD axion dark matter in a novel scenario, which assumes time-varying scale of Peccei-Quinn symmetry breaking. The latter decreases as the Universe's temperature at early times and eventually stabilises at a large constant value. Such behavior is caused by the portal interaction between the complex field carrying Peccei-Quinn charge and a Higgs-like scalar, which is in thermal equilibrium with primordial plasma. In this scenario, axions are efficiently produced during the parametric resonance decay of the complex Peccei-Quinn field, relaxing to the minimum of its potential in the radiation-dominated stage. Notably, this process is not affected by the Universe's expansion rate and allows to generate the required abundance of dark matter independently of an axion mass. Phenomenological constraints on the model parameter space depend on the number density of radial field fluctuations, which are also generically excited along with axions, and the rate of their thermalization in the primordial plasma. For the ratio of radial field and axion particles number densities larger than $\sim 0.01$ at the end of parametric resonance decay, the combination of cosmological and astrophysical observations with the CAST limit confines the Peccei-Quinn scale to a narrow range of values $\sim 10^{8}~\mbox{GeV}$, - this paves the way for ruling out our scenario with the near future searches for axions.
description: 28 pages, 3 figures; matches journal version
title: Hiperplasia Estromal Pseudoangiomatosa
Creators: name: Lerma Ortega, Rocio
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Breast
subject: Mammography
subject: Ultrasound

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
El objetivo de este póster es revisar una patología mamaria poco frecuente como es la Hiperplasia Estromal Pseudoangiomatosa (PASH),
que a pesar de ser un proceso benigno,
puede crear dudas en el diagnóstico tanto clínico como radiológico al...
title: Encefalitis postinfecciosa del tronco encéfalo en niños
Creators: name: Guijo Hernandez, Teresa
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Paediatric
subject: MR

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
La encefalitis de tronco cerebral (ETC) postinfecciosa en la edad infantil,
es un cuadro muy infrecuente,pero potencialmente reversible con tratamiento .
Algunos autores postulan que se trataría de una forma de ADEM que si bien no muestra lesiones...
A line profile-based double partial fusion method for acquiring planning CT of oversized patients in radiation treatment
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2012
Subjects: double scanning
partial registration
oversized patients
planning CT

description: True 3D CT dataset for treatment planning of an oversized patient is difficult to acquire due to the bore size and field of view (FOV) reconstruction. This project aims to provide a simple approach to reconstruct true CT data for oversize patients using CT scanner with limited FOV by acquiring double partial CT (left and right side) images. An efficient line profile-based method has been developed to minimize the difference of the CT numbers in the overlapping region between the right and left images and to generate a complete true 3D CT dataset in the natural state. New image processing modules have been developed and integrated to the Insight Segmentation & Registration Toolkit (ITK 3.6) package. For example, different modules for image cropping, line profile generation, line profile matching, and optimized partial image fusion have been developed. The algorithm has been implemented for images containing the bony structure of the spine and tested on 3D CT planning datasets from both phantom and real patients with satisfactory results in both cases. The proposed optimized line profile-based partial registration method provides a simple and accurate method for acquiring a complete true 3D CT dataset for an oversized patient using CT scanning with small bore size, that can be used for accurate treatment planning.
Averages of central L-values of Hilbert modular forms with an application to subconvexity
Creators: name: Feigon, Brooke
name: Whitehouse, David
Publisher: name: arXiv
Year: 2008
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11M41 (Primary), 11F72, 11F67 (Secondary)

description: We use the relative trace formula to obtain exact formulas for central values of certain twisted quadratic base change L-functions averaged over Hilbert modular forms of a fixed weight and level. We apply these formulas to the subconvexity problem for these L-functions. We also establish an equidistribution result for the Hecke eigenvalues weighted by these L-values.
description: 57 pages, minor changes made to version 1. The final version of this article will be published in the Duke Mathematical Journal, Vol. 149, No. 2, published by Duke University Press
The physical conditions in Gomez's Hamburger (IRAS 18059-3211), a pre-MS rotating disk
Creators: name: Bujarrabal, V.
name: Young, K.
name: Castro-Carrizo, A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We aim to study the structure, dynamics and physical conditions of Gomez's Hamburger (IRAS 18059-3211; GoHam). We confirm that GoHam essentially consists of a flaring disk in keplerian rotation around a young, probably pre-MS star. We present high resolution SMA maps of 12CO J=2-1, 13CO J=2-1, 12CO J=3-2, and C17O J=3-2, as well as data on 12CO J=6-5 and the continuum flux at these wavelengths. Spatial resolutions up to 1" are obtained. Except for the C17O data, the dynamical ranges are larger than 10. The maps are compared to a numerical model, which simulates the emission of a rotating disk with the expected general properties of such objects; a very satisfactory fitting of our maps is obtained. The meaning and reliability of our results are thoroughly discussed. Our observations allow measurement of the main properties of GoHam at scales between ~ 1" (~ 5 10^15 cm, for the assumed distance, 300 pc) and the total extent of the nebula, 14". We are able to measure the global structure of the gas-rich disk, which is found to be flaring, and its dynamics, which is clearly dominated by keplerian rotation, with a very small degree of turbulence. The combination of different lines, particularly showing different opacities, allows us to reasonably estimate the distributions of the gas temperature and density. We clearly find a significant and sharp increase in temperature at large distances from the equator, accompanied by a decrease in density of the same order. Finally, we identify and study a condensation in the southern part of the disk that has no counterparts in the rest of the nebula. This condensation is quite extended (about 5 10^15 cm), contains a significant amount of mass (roughly, ~ 6 10^-3 Mo), and seems to be associated with a detectable distortion of the global rotation kinematics.
description: 16 pages, 12 figures, 1 pdflatex text file, goha.bbl file, aa.cls style file
Biophysical and structural considerations for protein sequence evolution
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2011
Subjects: Amino Acid Sequence
Biophysics
Computer Simulation
Evolution, Molecular
Models, Molecular
Molecular Sequence Data
Protein Conformation
Protein Folding
Proteins
Thermodynamics

description: Background: Protein sequence evolution is constrained by the biophysics of folding and function, causing interdependence between interacting sites in the sequence. However, current site-independent models of sequence evolutions do not take this into account. Recent attempts to integrate the influence of structure and biophysics into phylogenetic models via statistical/informational approaches have not resulted in expected improvements in model performance. This suggests that further innovations are needed for progress in this field. Results: Here we develop a coarse-grained physics-based model of protein folding and binding function, and compare it to a popular informational model. We find that both models violate the assumption of the native sequence being close to a thermodynamic optimum, causing directional selection away from the native state. Sampling and simulation show that the physics-based model is more specific for fold-defining interactions that vary less among residue type. The informational model diffuses further in sequence space with fewer barriers and tends to provide less support for an invariant sites model, although amino acid substitutions are generally conservative. Both approaches produce sequences with natural features like dN/dS < 1 and gamma-distributed rates across sites. Conclusions: Simple coarse-grained models of protein folding can describe some natural features of evolving proteins but are currently not accurate enough to use in evolutionary inference. This is partly due to improper packing of the hydrophobic core. We suggest possible improvements on the representation of structure, folding energy, and binding function, as regards both native and non-native conformations, and describe a large number of possible applications for such a model. © 2011 Grahnen et al; licensee BioMed Central Ltd.
A dataset for multi-sensor drone detection
Creators: name: Svanström, Fredrik
name: Alonso-Fernandez, Fernando
name: Englund, Cristofer
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The use of small and remotely controlled unmanned aerial vehicles (UAVs), or drones, has increased in recent years. This goes in parallel with misuse episodes, with an evident threat to the safety of people or facilities. As a result, the detection of UAV has also emerged as a research topic. Most studies on drone detection fail to specify the type of acquisition device, the drone type, the detection range, or the dataset. The lack of proper UAV detection studies employing thermal infrared cameras is also an issue, despite its success with other targets. Besides, we have not found any previous study that addresses the detection task as a function of distance to the target. Sensor fusion is indicated as an open research issue as well, although research in this direction is scarce too. To counteract the mentioned issues and allow fundamental studies with a common public benchmark, we contribute with an annotated multi-sensor database for drone detection that includes infrared and visible videos and audio files. The database includes three different drones, of different sizes and other flying objects that can be mistakenly detected as drones, such as birds, airplanes or helicopters. In addition to using several different sensors, the number of classes is higher than in previous studies. To allow studies as a function of the sensor-to-target distance, the dataset is divided into three categories (Close, Medium, Distant) according to the industry-standard Detect, Recognize and Identify (DRI) requirements, built on the Johnson criteria. Given that the drones must be flown within visual range due to regulations, the largest sensor-to-target distance for a drone is 200 m, and acquisitions are made in daylight. The data has been obtained at three airports in Sweden: Halmstad Airport (IATA code: HAD/ICAO code: ESMT), Gothenburg City Airport (GSE/ESGP) and Malmö Airport (MMX/ESMS).
description: Published at Elsevier Data in Brief journal. arXiv admin note: text overlap with arXiv:2007.07396
Equivariant quantization of orbifolds
Creators: name: Poncin, N.
name: Radoux, F.
name: Wolak, R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Differential Geometry (math.DG)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 53D50; 53C12; 53B10; 53D20

description: Equivariant quantization is a new theory that highlights the role of symmetries in the relationship between classical and quantum dynamical systems. These symmetries are also one of the reasons for the recent interest in quantization of singular spaces, orbifolds, stratified spaces... In this work, we prove existence of an equivariant quantization for orbifolds. Our construction combines an appropriate desingularization of any Riemannian orbifold by a foliated smooth manifold, with the foliated equivariant quantization that we built in \cite{PoRaWo}. Further, we suggest definitions of the common geometric objects on orbifolds, which capture the nature of these spaces and guarantee, together with the properties of the mentioned foliated resolution, the needed correspondences between singular objects of the orbifold and the respective foliated objects of its desingularization.
description: 13 pages
Wavelength-shifter coated polystyrene as an easy-to-build and low-cost plastic scintillator detector
Creators: name: Brignoli, A.
name: Conaboy, A.
name: Dormenev, V.
name: Jimeno, D.
name: Kazlou, D.
name: Lacker, H.
name: Scharf, C.
name: Schmidt, J.
name: Zaunick, H. G.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We studied the light yield of a pure polystyrene slide coated with wavelength-shifter molecules, coupled to a photomultiplier, using beta particles from a 90-Sr source, as a possible easy-to-build, low-cost plastic scintillator detector. Comparison measurements were performed with an uncoated polystyrene slide as well as with uncoated and coated PMMA slides, the latter which can only produce Cherenkov light when being traversed by charged particles. The results with the single (double) coated polystyrene slides show about 4.9 (6.3) times higher detected photon yield compared to the uncoated slide. For comparison, the light yield of a polystyrene-based extruded plastic scintillator material doped with PTP and POPOP was measured as well. The absolute detected light yield motivates future studies for developing easy-to-build, low-cost polystyrene-based plastic scintillator detectors.
description: 20 pages, 13 figures
The role of chlamydia trachomatis polymorphic membrane proteins in inflammation and sequelae among women with pelvic inflammatory disease
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2011
Subjects: Adult
Antibodies, Bacterial
Bacterial Outer Membrane Proteins
Chlamydia Infections
Chlamydia trachomatis
Female
Fertility
Humans
Pelvic Inflammatory Disease
Pilot Projects
Pregnancy
Pregnancy Outcome

description: Chlamydia trachomatis polymorphic membrane proteins (Pmps) may increase genital tract inflammation and play a role in virulence. Antibody levels for PmpA, PmpD, and PmpI, measured in densitometric units, were assessed among a pilot sample of 40 C. trachomatis-infected women with mild-to-moderate clinical PID. Women who expressed antibodies to PmpA were less likely to achieve pregnancy (40.0 versus 85.7; P = 0.042) and less likely to have a live birth (0.0 versus 80.0; P = 0.005) compared to women who did not express antibody to PmpA. Women who expressed antibodies to PmpI were more likely to have upper genital tract infection (61.5 versus 20.0; P = 0.026). However, seropositivity to PmpI and PmpD did not modify the risk of reproductive sequelae or inflammation. Seropositivity to chlamydial PmpA may represent a biomarker of increased risk of sequelae secondary to infection with C. trachomatis. © 2011 Brandie D. Taylor et al.
The THREEHUNDRED project: the effect of baryon processes at galaxy cluster scale
Creators: name: Cui, Weiguang
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The role of baryon models played in hydrodynamic simulations is still unclear. Future surveys that use cluster statistics to precisely constrain cosmology models require a better understanding of that. With the hydro-simulated galaxy clusters from different baryon models (Gadget-MUSIC, Gadget-X and Gizmo-SIMBA) from the THREEHUNDRED project, we can look into more details of this question. We find that the galaxy cluster mass change due to different baryon models is at a few per cent level. However, the mass changes can be positive or negative, which is depending on the baryon models. Such a small mass change leaves a weak influence (slightly larger compared to the mass changes) on both the cumulative halo numbers and the differential halo mass function (HMF) above the mass completeness. Agreed to the halo mass change, the halo mass (or HMF) can be increased or decreased with respect to the dark-matter-only (DMO) run depending on the baryon models.
description: To appear in the Proceedings of the International Conference entitled "mm Universe @ NIKA2", Rome (Italy), June 2021, EPJ Web of conferences
Reconnection-Driven Energy Cascade in Magnetohydrodynamic Turbulence
Creators: name: Dong, Chuanfei
name: Wang, Liang
name: Huang, Yi-Min
name: Comisso, Luca
name: Sandstrom, Timothy A.
name: Bhattacharjee, Amitava
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Computational Physics (physics.comp-ph)
subject: Plasma Physics (physics.plasm-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: Magnetohydrodynamic turbulence regulates the transfer of energy from large to small scales in many astrophysical systems, including the solar atmosphere. We perform three-dimensional magnetohydrodynamic simulations with unprecedentedly large magnetic Reynolds number to reveal how rapid reconnection of magnetic field lines changes the classical paradigm of the turbulent energy cascade. By breaking elongated current sheets into chains of small magnetic flux ropes (or plasmoids), magnetic reconnection leads to a new range of turbulent energy cascade, where the rate of energy transfer is controlled by the growth rate of the plasmoids. As a consequence, the turbulent energy spectra steepen and attain a spectral index of -2.2 that is accompanied by changes in the anisotropy of turbulence eddies. The omnipresence of plasmoids and their consequences on, e.g., solar coronal heating, can be further explored with current and future spacecraft and telescopes.
description: 32 pages, 8 figures, the world's largest 3D MHD turbulence simulation using a fifth-order scheme
Processed data from somatic WES
Creators: name: Pokorna, Petra
Publisher: name: figshare
Year: 2021
Subjects: Cancer

description: Processed whole-exome sequencing data for patient's somatic exome related to "Minimal disseminated disease guided intermittent dosing in cancer patients: Successful treatment of chemoresitant anaplastic large cell lymphoma using intermittent lorlatinib dosing" article.
The effects of ration type and ralgro implantation on the growth rate, feed efficiency and carcass composition of Hereford steers
Creators: name: Nwokolo, Emmanuel R. N.
Publisher: name: University of British Columbia
Year: 2010

description: Five ration types as well as Ralgro implantation were evaluated in a 5 x 2 factorial experiment to determine their effect on growth rate, feed efficiency and carcass composition of Hereford steers. The five ration types were 100% barley, 50% barley-50% alfalfa cubes, 100% alfalfa cubes, barley followed by cubes, and cubes followed by barley. Implantation of 36 mg Ralgro was done after 12 weeks on the experimental diet. The animals were weighed every two weeks, the morning feed being withheld until weighing had been completed. Rib eye muscle area as well as fat depth over the eye muscle were used to estimate carcass lean and carcass fat. Rib eye area and fat thickness were measured monthly using a USM 2F Krautkramer Ultrasonic flaw detector. The feeding trials lasted 28 to 36 weeks at the end of which the steers were probed for rib eye area and fat depth. They were then starved for 12 hours, weighed and shipped to a packing house. Rib eye muscle area and fat thickness were determined on the chilled carcasses. Dressing percentage as well as cutability were also determined on each carcass. The carcasses were then graded. Average daily gain, group feed efficiency and feed cost/kg gain were computed for each ration type. Results indicated that only the 100%, alfalfa ration supported significantly lower average daily gain (P≤0.05) than other rations. There were no differences between the ration types in terms of the average carcass fat and carcass lean. The 100% barley ration, the 50%, barley ration as well as the ration in which alfalfa was followed by barley, all gave rise to significantly higher dressing percentages (P≤0.05). Over the entire growth period, implantation of 36 mg Ralgro did not significantly improve either the growth rate or the carcass composition of the steers so treated. A breakdown of the growth period indicated that within 60 days post implantation, administration of 36 mg Ralgro caused a significantly higher growth rate than controls. Its effect, however, disappeared after 60 days. There were significant but low positive correlations between the area of rib eye estimated by the ultrasonic method just prior to slaughter and that determined on the carcass by acetate paper tracings (r = 0.27) or by the plastic grid method (r = 0.30). There was, however, a very high correlation (r = 0.72) between the acetate paper tracings and the plastic grid method of determining the area of rib eye muscle. Computation of the feed cost/kg gain indicated that at prevailing prices the all-barley ration was the cheapest to raise steers on while the all-alfalfa ration was by far the most expensive.
L'associazione Tipifarnib-Bortezomib nel trattamento delle leucemie acute mieloidi: risultati di uno studio multicentrico di fase I/II e validazione di un profilo genico predittivo di risposta
Creators: name: Paolini, Stefania <1978>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2011
Subjects: MED/15 Malattie del sangue

description: Background. Outcome of elderly acute myeloid leukemia (AML) patients is dismal. Targeted-therapies might improve current results by overcoming drug-resistance and reducing toxicity.   
Aim. We conduced a phase II study aiming to assess efficacy and toxicity of Tipifarnib (Zarnestra®) and Bortezomib (Velcade®) association in AML patients >18 years, unfit for conventional therapy, or >60 years, in relapse. Furthermore, we aimed to evaluated the predictive value of the RASGRP1/APTX ratio, which was previously found to be associated to treatment sensitivity in patients receiving Zarnestra alone. 
Methods. Velcade (1.0 mg/m2) was administered as weekly infusion for 3 weeks (days 1, 8, 15). Zarnestra was administered at dose of 300-600 mg BID for 21 consecutive days. Real-time quantitative-PCR (q-PCR) was used for RASGRP1/APTX quantification. 
Results. 50 patients were enrolled. Median age was 71 years (56-89). 3 patients achieved complete remission (CR) and 1 partial response (PR). 2 patients obtained an hematological improvement (HI), and 3 died during marrow aplasia. 10 had progressive disease (PD) and the remaining showed stable disease (SD). RASGRP1/APTX was evaluated before treatment initiation on bone marrow (BM) and/or peripheral blood (PB). The median RASGRP/APTX value on BM was higher in responder (R) patients than in non responders (NR) ones, respectively (p=0.006). Interestingly, no marrow responses were recorded in patients with BM RASGRP1/APTX ratio <12, while the response rate was 50% in patients with ratio >12. Toxicity was overall mild, the most common being febrile neutropenia.
Conclusion. We conclude that the clinical efficacy of the combination Zarnestra-Velcade was similar to what reported for Zarnestra alone. However we could confirm that the RASGPR1/APTX level is an effective predictor of response. Though higher RASGRP1/APTX is relatively rare (~10% of cases), Zarnestra (±Velcade) may represent an important option in a subset of high risk/frail AML patients.
Electric and anomalous magnetic dipole moments of the muon in the MSSM
Creators: name: Cheung, Kingman
name: Kong, Otto C. W.
name: Lee, Jae Sik
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the electric dipole moment (EDM) and the anomalous magnetic dipole moment (MDM) of the muon in the CP-violating Minimal Supersymmetric extension of the Standard Model (MSSM). We take into account the contributions from the chargino- and neutralino-mediated one-loop graphs and the dominant two-loop Higgs-mediated Barr-Zee diagrams. We improve earlier calculations by incorporating CP-violating Higgs-boson mixing effects and the resummed threshold corrections to the Yukawa couplings of the charged leptons as well as that of the bottom quark. The analytic correlation between the muon EDM and MDM is explicitly presented at one- and two-loop levels and, through several numerical examples, we illustrate its dependence on the source of the dominant contributions. We have implemented the analytic expressions for the muon EDM and MDM in an updated version of the public code CPsuperH2.0.
description: 26 pages, 10 figures, references added, more references added, to appear in JHEP
Q-factor optimization for high-beta 650 MHz cavities for PIP-II
Creators: name: Martinello, M.
name: Bice, D. J.
name: Boffo, C.
name: Chandrasekeran, S. K.
name: Eremeev, G. V.
name: Furuta, F.
name: Grassellino, A.
name: Melnychuk, O.
name: Sergatskov, D. A.
name: Wu, G.
name: Reid, T. C.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: High Q-factors are of utmost importance to minimize losses of superconducting radio-frequency cavities deployed in continuous wave particle accelerators. This study elucidates the surface treatment that can maximize the Q-factors in high-beta 650 MHz elliptical niobium cavities. State-of-the-art surface treatments are applied in many single-cell cavities, and surface resistance studies are performed to understand the microwave dissipation at this unexplored frequency. The nitrogen doping treatment is confirmed to be necessary to maximize the Q-factors at medium RF fields. We applied this treatment in five-cell high-beta 650 MHz cavities and demonstrated that extremely high Q-factors were obtained at medium RF fields with this treatment. We also demonstrated that adding a cold electropolishing step after N-doping is crucial to push the quench field of multicell cavities to higher gradients.
Mycoplasma genitalium: An emerging cause of pelvic inflammatory disease
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2011
Subjects: Adult
Anti-Bacterial Agents
Female
Humans
Infertility
Mycoplasma Infections
Mycoplasma genitalium
Pelvic Inflammatory Disease

description: Mycoplasma genitalium is a sexually transmitted pathogen that is increasingly identified among women with pelvic inflammatory disease (PID). Although Chlamydia trachomatis and Neisseria gonorrhoeae frequently cause PID, up to 70% of cases have an unidentified etiology. This paper summarizes evidence linking M. genitalium to PID and its long-term reproductive sequelae. Several PCR studies have demonstrated that M. genitalium is associated with PID, independent of gonococcal and chlamydial infection. Most have been cross-sectional, although one prospective investigation suggested that M. genitalium was associated with over a thirteenfold risk of endometritis. Further, a nested case-control posttermination study demonstrated a sixfold increased risk of PID among M. genitalium positive patients. Whether or not M. genitalium upper genital tract infection results in long-term reproductive morbidity is unclear, although tubal factor infertility patients have been found to have elevated M. genitalium antibodies. Several lines of evidence suggest that M. genitalium is likely resistant to many frequently used PID treatment regimens. Correspondingly, M. genitalium has been associated with treatment failure following cefoxitin and doxycycline treatment for clinically suspected PID. Collectively, strong evidence suggests that M. genitalium is associated with PID. Further study of M. genitalium upper genital tract infection diagnosis, treatment and long-term sequelae is warranted. Copyright © 2011 Catherine L. Haggerty and Brandie D. Taylor.