cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Development of Receptors for Posttranslationally Modified Peptides in Water
Creators: name: Beaver, Joshua
Publisher: name: University of North Carolina at Chapel Hill Graduate School
Year: 2015
Subjects: Chemistry, Organic
Chemistry
Molecules

description: The work presented in this dissertation highlights recent progress and advances in using dynamic combinatorial chemistry (DCC) for the investigation of molecular recognition in water. In particular, this work emphasizes the selective recognition of posttranslational modifications of histone proteins in the context of peptides through differential non-covalent interactions. DCC was used to identify and synthesize small molecule receptors, in the form of amphiphilic macrocycles with aromatic interiors and anionic exteriors, which bind to modified amino acids with protein-like affinity and selectivity. Advances in supramolecular and materials chemistry continue to expound upon the limits of molecular recognition. The progression of biotechnology in cancer research and the development of green materials, emphasizes the importance of controlling and predicting the non-covalent interactions that drive molecular recognition in water. Understanding posttranslational modifications of histone proteins has been the focus of intense research in recent years, due to their critical involvement in the control of gene transcription. Iterative redesign of a previously identified synthetic receptor that binds to trimethyllysine with affinity and selectivity comparable to the HP1 chromodomain led to the identification of a small molecule receptor with an expanded binding pocket and aromatic surface that recognizes asymmetric dimethylarginine (RaMe2). The size of the binding pocket limited binding to symmetric dimethyl arginine (RsMe2), leading to preferential binding of RaMe2. DCC was also used to conduct a structure function study of previously identified receptors in order to investigate the influences of structure and electrostatic interactions on binding affinity to methylated lysine derivatives. Parallels in relationship to binding pocket depth, were observed between the binding selectivity of native proteins for various methylated lysines and small molecule receptors. The influence of electrostatic interactions on affinity and selectivity revealed that additional carboxylate-ammonium interactions can improve binding affinity, but do not significantly affect selectivity between methylation states of lysine. Non-covalent influences on binding to 3-nitrotyrosine, a product of oxidative stress and important biomarker for disease, were also investigated using DCC. A potential scaffold for selective binding to 3NT over tyrosine was identified and a variety of novel DCC monomers was developed for use in future iterative redesign studies.
Hybrid leg compliance enables robots to operate with sensorimotor delays and low control update frequencies
Creators: name: Ashtiani, Milad Shafiee
name: Sarvestani, Alborz Aghamaleki
name: Badri-Spröwitz, Alexander
Publisher: name: arXiv
Year: 2021
Subjects: subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Animals locomote robustly and agile, albeit significant sensorimotor delays of their nervous system. The sensorimotor control of legged robots is implemented with much higher frequencies-often in the kilohertz range-and sensor and actuator delays in the low millisecond range. But especially at harsh impacts with unknown touch-down timing, legged robots show unstable controller behaviors, while animals are seemingly not impacted. Here we examine this discrepancy and suggest a hybrid robotic leg and controller design. We implemented a physical, parallel joint compliance dimensioned in combination with an active, virtual leg length controller. We present an extensive set of systematic experiments both in computer simulation and hardware. Our hybrid leg and controller design shows previously unseen robustness, in the presence of sensorimotor delays up to 60 ms, or control frequencies as low as 20 Hz, for a drop landing task from 1.3 leg lengths high and with a passive compliance ratio of 0.7. In computer simulations, we report successful drop-landings of the hybrid compliant leg from 3.8 leg lengths (1.2 m) for a 2 kg quadruped robot with 100 Hz control frequency and a sensorimotor delay of 35 ms. The results of our presented hybrid leg design and control provide a further explanation for the performance robustness of animals, and the resulting discrepancy between animals and legged robots.
A simple method for estimating the fractal dimension from digital images: The compression dimension
Creators: name: Chamorro-Posada, P.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Graphics (cs.GR)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The fractal structure of real world objects is often analyzed using digital images. In this context, the compression fractal dimension is put forward. It provides a simple method for the direct estimation of the dimension of fractals stored as digital image files. The computational scheme can be implemented using readily available free software. Its simplicity also makes it very interesting for introductory elaborations of basic concepts of fractal geometry, complexity, and information theory. A test of the computational scheme using limited-quality images of well-defined fractal sets obtained from the Internet and free software has been performed. Also, a systematic evaluation of the proposed method using computer generated images of the Weierstrass cosine function shows an accuracy comparable to those of the methods most commonly used to estimate the dimension of fractal data sequences applied to the same test problem.
Acute Effect of Altered Mechanical Loading on Biomechanics and Biochemical Markers in Individuals with Anterior Cruciate Ligament Reconstruction
Creators: name: Harkey, Brittney
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Context: The complex interaction between aberrant mechanical loading and altered cartilage metabolism is hypothesized to lead to the development of posttraumatic osteoarthritis (PTOA) following anterior cruciate ligament reconstruction (ACLR). There is a critical need for effective therapeutic strategies that are capable of manipulating mechanical loading for the purpose of maintaining homeostatic cartilage metabolism following ACLR. Objective: To utilize real-time biofeedback to acutely increase (i.e. overloading), acutely decrease (i.e. under-loading) and promote symmetrical loading between limbs during walking gait in individuals with ACLR to determine changes in lower extremity biomechanical outcomes and cartilage metabolism that occur following acute bouts of altered mechanical loading. Participants: 30 individuals with a primary, unilateral ACLR. Interventions: Participants completed four testing sessions. One of four loading conditions was completed during 20 minutes of treadmill walking, and included 1) control condition of normal walking, 2) a 5% increase (i.e. overloading) in peak vGRF, 3) a 5% decrease (i.e. under-loading) in peak vGRF, and 4) symmetrical peak vGRF between limbs. Main Outcome Measures: Root mean square error (RMSE) was calculated during the acquisition and recall periods. Lower biomechanical outcomes included peak vGRF, instantaneous vGRF loading rate, peak KEM, and knee flexion excursion. Catilage metabolism was quantified using serum oligomeric matrix protein (COMP). Results: Individuals with ACLR demonstrate lesser RMSE during the acquisition of symmetrical loading as compared to the overloading and under-loading conditions. Peak vGRF was significantly greater during the overloading condition, and significantly lesser during the under-loading condition as compared to the control condition. Peak KEM and knee flexion excursion were significantly greater during the overloading condition as compared to the under-loading condition. Individuals with ACLR demonstrating an increase in COMP during the control condition demonstrated a significant decrease in COMP during the overloading condition as compared to the control. Individuals with ACLR demonstrating a lesser baseline peak vGRF also demonstrated a greater increase in COMP following 20 minutes of normal walking. Conclusions: Real-time biofeedback may be beneficial for altering mechanical loading during walking gait in individuals with ACLR. Acutely manipulating mechanical during walking gait may be able to influence cartilage metabolism in individuals with ACLR.
An End-To-End-Trainable Iterative Network Architecture for Accelerated Radial Multi-Coil 2D Cine MR Image Reconstruction
Creators: name: Kofler, Andreas
name: Haltmeier, Markus
name: Schaeffter, Tobias
name: Kolbitsch, Christoph
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Image and Video Processing (eess.IV)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Purpose: Iterative Convolutional Neural Networks (CNNs) which resemble unrolled learned iterative schemes have shown to consistently deliver state-of-the-art results for image reconstruction problems across different imaging modalities. However, because these methodes include the forward model in the architecture, their applicability is often restricted to either relatively small reconstruction problems or to problems with operators which are computationally cheap to compute. As a consequence, they have so far not been applied to dynamic non-Cartesian multi-coil reconstruction problems. Methods: In this work, we propose a CNN-architecture for image reconstruction of accelerated 2D radial cine MRI with multiple receiver coils. The network is based on a computationally light CNN-component and a subsequent conjugate gradient (CG) method which can be jointly trained end-to-end using an efficient training strategy. We investigate the proposed training-strategy and compare our method to other well-known reconstruction techniques with learned and non-learned regularization methods. Results: Our proposed method outperforms all other methods based on non-learned regularization. Further, it performs similar or better than a CNN-based method employing a 3D U-Net and a method using adaptive dictionary learning. In addition, we empirically demonstrate that even by training the network with only iteration, it is possible to increase the length of the network at test time and further improve the results. Conclusions: End-to-end training allows to highly reduce the number of trainable parameters of and stabilize the reconstruction network. Further, because it is possible to change the length of the network at test time, the need to find a compromise between the complexity of the CNN-block and the number of iterations in each CG-block becomes irrelevant.
Bulk universality for random lozenge tilings near straight boundaries and for tensor products
Creators: name: Gorin, Vadim
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We prove that the asymptotic of the bulk local statistics in models of random lozenge tilings is universal in the vicinity of straight boundaries of the tiled domains. The result applies to uniformly random lozenge tilings of large polygonal domains on triangular lattice and to the probability measures describing the decomposition in Gelfand-Tsetlin bases of tensor products of representations of unitary groups. In a weaker form our theorem also applies to random domino tilings.
description: 27 pages, 11 figures. v2: inconsistency in Section 4 notations corrected
title: The Impact of Building Certificates in regard to the implementation of relevant SDGs using the example of Austrian Office Buildings
Creators: name: Backmeister, Hannah
Publisher: name: TU Wien
Year: 2023
Subjects: subject: Building Certificates
subject: SDG

description: In light of this years ́ 30th anniversary of the adoption of the United Nations Framework Convention on Climate Change, the world still faces a critical decade for climate action. Therefore, the Conference of the Parties (COP 27) deliberated on further initiatives to cut global emissions. (UN, 2022) Given the complexity where threats of climate change equally affect the “welfare, prosperity and integrity of people and the planet”, COP27 promoted the 2030 Agenda once more. (EN, 2021, p. 3) Therefore, the thesis at hand focuses on interlinkages and interdependencies of relevant Sustainable Development Goals (SDGs), providing particular reference to the Austrian real estate sector. Hence, the compliance of two selected building certificates, ÖNGI and WELL, are elaborated, presenting their added value for all parties involved. In this regard, building certificates not only provide performance indicators (PIs) of a building’s operation but also benefit the corporates’ identity by highlight additional effort of businesses and developers. However, the ME310 prototype demonstrated once more that merely technical solutions do not achieve-long term sustainability if tenant ́s intentions regarding sustainability have not been changed. (Biggio & Cortese, 2013) Discussing therefore the attitude-behavior gap, the contribution of green leases is also raised. Yet, the implementation of the 17 SDGs not only requires horizontal demand, but also vertical legislation. (Frantz, 2016) Therefore, the thesis finally considers Austrian legislation and European policy revisions by discussing ESG alignment of the theoretical comparison of GBS and the 2030 Agenda.
Numerical simulations of bumblebee hovering flights using the passive feathering model
Creators: name: Kolomenskiy, Dmitry
name: Ravi, Sridhar
name: Xu, Ru
name: Ueyama, Kohei
name: Jakobi, Timothy
name: Engels, Thomas
name: Nakata, Toshiyuki
name: Sesterhenn, Joern
name: Schneider, Kai
name: Onishi, Ryo
name: Liu, Hao
Publisher: name: Open Science Framework
Year: 2022

description: Input and output files from numerical simulations of bumblebee hovering flights using the passive feathering model. FluSI, a computational fluid dynamics solver, is combined with a dynamical model that describes the wing motion. The model consists of the wings approximated as flat plates, connected with the body by elastic hinges.
The Relationship of Ethics Education to Moral Sensitivity and Moral Reasoning of Students in Baccalaureate Nursing Programs of South Korea
Creators: name: Park, Mihyun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The purposes of this study were to describe the relationships 1) between academic class and moral sensitivity and moral reasoning of students in baccalaureate nursing programs in South Korea, 2) between curriculum design components for ethics education and moral sensitivity and moral reasoning, and 3) between student characteristics, and moral sensitivity and moral reasoning. This study has a descriptive design using preexisting groups to explore the relationships between multiple variables and the student outcome variables. Data were collected by surveying freshman and senior students in eight private baccalaureate nursing programs in the Seoul metropolitan area in South Korea. The survey consisted of a demographic form, the Korean Moral Sensitivity Questionnaire to examine moral sensitivity of students, and the Korean Defining Issues Test to examine moral reasoning of students. To examine the relationships, this study used mixed models for analysis of clustered data within schools. According to the results of this study, there were significant relationships between: 1) academic class and moral sensitivity, 2) curricular variables (i.e., hours of ethics content and hours of non-lecture teaching methods) and moral reasoning, 3) student characteristics, age, gender, and number of siblings, and moral sensitivity, and 4) student characteristics, religion and GPA, and moral reasoning. The findings of this study indicate that nursing education in South Korea may have an impact on developing student moral sensitivity, particularly, in caring relationship with patients (b =1.44, SE=.36, p<.001) and in expression of conflict in moral dilemma situations (b =.94, SE=.44, p<.05). However, specific ethics education provided by the programs was significantly associated with student moral reasoning rather than moral sensitivity; more hours of ethics content increased the principled thinking scores of senior students (b =.26, SE=.12, p<.05). Nursing programs in South Korea need to stress the principled reasoning of students and consider that planned ethics content in a nursing curriculum can improve moral sensitivity and moral reasoning of students based on understanding the influence of student characteristics on student moral development. Further research to test the effect of a specific curriculum intervention on the moral development of students is suggested.
Natural orbital description of the halo nucleus 6He
Creators: name: Constantinou, Ch.
name: Caprio, M. A.
name: Vary, J. P.
name: Maris, P.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Ab initio calculations of nuclei face the challenge of simultaneously describing strong short-range internucleon correlations and the long-range properties of weakly-bound halo nucleons. Natural orbitals, which diagonalize the one-body density matrix, provide a basis which is better matched to the physical structure of the many-body wave function. We demonstrate that the use of natural orbitals significantly improves convergence for ab initio no-core configuration interaction calculations of the neutron halo nucleus 6He, relative to the traditional oscillator basis.
description: 6 pages, 4 figures; presented at the Symposium on Nuclear Dynamics and Thermodynamics, Huizhou, China, December 11, 2016; as published in Nucl. Sci. Tech
Rotational spectra of isotopic species of methyl cyanide, CH$_3$CN, in their $v_8 = 1$ excited vibrational states
Creators: name: Müller, H. S. P.
name: Drouin, B. J.
name: Pearson, J. C.
name: Ordu, M. H.
name: Wehres, N.
name: Lewen, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Methyl cyanide is an important trace molecule in space, especially in star-forming regions where it is one of the more common molecules used to derive kinetic temperatures. We want to obtain accurate spectroscopic parameters of minor isotopologs of methyl cyanide in their lowest excited $v_8 = 1$ vibrational states to support astronomical observations, in particular, with interferometers such as ALMA. The laboratory rotational spectrum of methyl cyanide in natural isotopic composition has been recorded from the millimeter to the terahertz regions. Transitions with good signal-to-noise ratios could be identified for the three isotopic species CH$_3^{13}$CN, $^{13}$CH$_3$CN, and CH$_3$C(15)N up to about 1.2 THz ($J'' \le 66$). Accurate spectroscopic parameters were obtained for all three species. The present data were already instrumental in identifying $v_8 = 1$ lines of methyl cyanide with one $^{13}$C in IRAM 30 m and ALMA data toward Sagittarius B2(N).
description: 6 pages, 1 figure, article appeared; CDMS links and two references updated
Relationship Between Freestyle Biomechanical Errors and Shoulder Pain in Elite Competitive Swimmers
Creators: name: Virag, Bonnie Jean
Publisher: name: University of North Carolina at Chapel Hill
Year: 2012

description: Biomechanical freestyle stroke errors are thought to be risk factors for the development of shoulder pain among swimmers. The aim of this study was to examine the relationship between freestyle stroke biomechanical errors and shoulder pain in elite competitive swimmers. Thirty-one swimmers from an elite competitive population completed two Penn Shoulder Score questionnaires (one per shoulder) for evaluation of shoulder pain, satisfaction, and function. Each swimmer was instructed to swim freestyle for two lengths of a 25 yard competitive swimming pool which was filmed from both above water and underwater cameras, providing frontal and lateral views. The biomechanics were analyzed and clipped using Dartfish TeamPro(TM) software. Presence of errors was determined by selected evaluators and this data was used to determine if freestyle biomechanical errors predicted shoulder pain. Neither the total number of biomechanical freestyle errors, nor any of the specific errors were predictive of the PENN shoulder pain score.
Constructions of $\ell$-Adic $t$-Deletion-Correcting Quantum Codes
Creators: name: Matsumoto, Ryutaroh
name: Hagiwara, Manabu
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We propose two systematic constructions of deletion-correcting codes for protecting quantum information. The first one works with qudits of any dimension, but only one deletion is corrected and the constructed codes are asymptotically bad. The second one corrects multiple deletions and can construct asymptotically good codes. The second one also allows conversion of stabilizer-based quantum codes to deletion-correcting codes, and entanglement assistance.
description: LaTeX2e, 6 pages, no figure, version 2 only corrects typos
Phenomenology of the simple 3-3-1 model with inert scalars
Creators: name: Van Dong, Phung
name: Ngan, N. T. K.
name: Tham, T. D.
name: Thien, L. D.
name: Thuy, N. T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The simple 3-3-1 model that contains the minimal lepton and minimal scalar contents is detailedly studied. The impact of the inert scalars (i.e., the extra fundamental fields that provide realistic dark matter candidates) on the model is discussed. All the interactions of the model are derived, in which the standard model ones are identified. We constrain the standard model like Higgs particle at the LHC. We search for the new particles including the inert ones, which contribute to the $B_s$-$\bar{B}_s$ mixing, the rare $B_s\rightarrow μ^+μ^-$ decay, the CKM unitarity violation, as well as producing the dilepton, dijet, diboson, diphoton, and monojet final states at the LHC.
description: 41 pages, 5 figures, 14 tables; substantially improved and enlarged with added references; new contributors included
D-JRP15-FED-AMR-WP6.4 (Submission/publication of 1/2 paper(s) on how resilience of microbial communities depends on external environmental drivers and richness and diversity of the community
Creators: name: Cabal Rosel, Adriana
name: Lo Iacono, Giovanni
Publisher: name: Zenodo
Year: 2022
Subjects: FED-AMR
resilience
microbial communities

description: D-JRP15-FED-AMR-WP6.4 reports on the effect that environmental factors have on the prevalence of antibiotic resistance in the non-built environment . The outcome is a protocol for a systematic evidence map that has been published in Environment International.
Digital Power for RMS & PF Meter Using Microprocessor
Creators: name: Alali, Walid Y
Publisher: name: figshare
Year: 2022
Subjects: Interaction and experience design
Software engineering not elsewhere classified
Engineering design

description: This paper uses a digital sampling technique to measure the power RMS and power factor values. It is controlled by a microprocessor 8085. This technique performs simultaneous sampling at equal time intervals over the period of both the input voltage and the current signals. It measures the required measurement value by calculating the numerical values of the synchronous input voltage and current samples. The stated system accuracy is ± 0 05% class. The output result is presented to 5 decimal places on the display unit, with the lead sign indicated.
UV Completions for Non-Critical Strings
Creators: name: Apruzzi, Fabio
name: Hassler, Falk
name: Heckman, Jonathan J.
name: Melnikov, Ilarion V.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Compactifications of the physical superstring to two dimensions provide a general template for realizing 2D conformal field theories coupled to worldsheet gravity, i.e. non-critical string theories. Motivated by this observation, in this paper we determine the quasi-topological 8D theory which governs the vacua of 2D N = (0,2) gauged linear sigma models (GLSMs) obtained from compactifications of type I and heterotic strings on a Calabi-Yau fourfold. We also determine the quasi-topological 6D theory governing the 2D vacua of intersecting 7-branes in compactifications of F-theory on an elliptically fibered Calabi-Yau fivefold, where matter fields and interaction terms localize on lower-dimensional subspaces, i.e. defect operators. To cancel anomalies / cancel tadpoles, these GLSMs must couple to additional chiral sectors, which in some cases do not admit a known description in terms of a UV GLSM. Additionally, we find that constructing an anomaly free spectrum can sometimes break supersymmetry due to spacetime filling anti-branes. We also study various canonical examples such as the standard embedding of heterotic strings on a Calabi-Yau fourfold and F-theoretic "rigid clusters" with no local deformation moduli of the elliptic fibration.
description: v4: 102 pages, 2 figures, clarifications added
The application of low energy photon ionization to heterogeneous aerosol chemistry
Creators: name: Nash, David Gerald.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The first part of this dissertation is a review of developments made in the field of aerosol mass spectrometry. The focus of the research is on the reduction of fragmentation observed in the mass spectra of organic molecules and its application to studying the reactivity of more realistic aerosol particles. Initial studies examined reduction in oleic acid fragmentation with lower energy (8.75 eV) photons generated using resonance difference frequency mixing (RDFM), a form of four wave mixing. In the same study, the effects of different particle vaporization methods on the ion production mechanism are discussed. Understanding both of these issues is very important to accurate kinetics studies. These findings were then applied to the study of the reactivity of mixed myristic acid/oleic acid particles. While still not as complex as typical atmospheric particles, studying particles consisting of a binary mixture, especially the ones studied here which can undergo phase changes with changing relative composition is an important first step in understanding issues such as why the lifetime of oleic acid as measured in the field is longer than what would be predicted from laboratory studies. Our study of mixed particles demonstrates reduced reactivity upon crystallization of myristic acid. Possibilities for the way in which crystallization would have to occur to result in the observed degree of decreased reactivity are also discussed.
THE ACTIVATION AND CONSEQUENCES OF THE ATM MEDIATED DNA DAMAGE RESPONSE IN HPV INFECTED CELLS
Creators: name: Johnson, Bryan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Infection with Human papillomavirus (HPV) is the most prevalent sexually transmitted disease in the world. From a public health standpoint, a subset of mucosa-tropic HPVs termed the high-risk genotypes are of most concern, as they are the causative agents of over 99 percent of cervical cancers and are increasingly linked to other forms of cancer. HPV initially infects the basal keratinocytes of the host epithelium and subsequently undergoes a life cycle tightly linked to the differentiation of its host cell. Despite having a small coding capacity, HPV is a master manipulator of the host cell, subverting a number pathways in order to ensure its own replication. Manipulation of the host cell is largely achieved through the expression of HPV’s two major oncoproteins, E6 and E7, to dysregulate p53 and Rb-E2F signaling respectively. This dissertation examines the function of the E7 protein in the viral life cycle. E7 expression has been linked previously to the activation of the ATM DNA damage repair pathway throughout infection and the induction of G2 arrest in the upper layers of the stratified epithelium. Here I show that deletion of the Rb binding domain of E7 ablates its ability to increase the levels of ATM pathway proteins in HPV positive cells. Additionally, I demonstrate that E7 broadly upregulates the stability of DNArepair factors to increase their levels, regulating the transcription of only a subset of factors. I also show that the activity of the ATM kinase is necessary to increase the levels of proteins regulating the G2/M checkpoint, but does not play a role in increasing the levels of most DNA repair factors. Together, these data establish a model for ATM activation by E7 during HPV infection.
Benefit-Cost Analysis of Municipal Rural and Industrial System on Crow Reservation Montana
Creators: name: Reichhardt, Tasha
Publisher: name: Unknown
Year: 2023
Subjects: Demand and Price Analysis
Environmental Economics and Policy

description: There is currently little research about the economic outcomes for tribes that settle their water rights with the United States. To address this gap, I conduct a benefit-cost analysis on the Crow Reservation’s Municipal, Rural, and Industrial System funded by the Crow Tribe Water Rights Settlement Act of 2010. This project is designed to revitalize the existing community water systems on Crow Reservation and provide community water access to over half of the reservation's residents that otherwise rely on wells, springs, or hauling water. I also discuss the implications this may have for tribes unable or ineligible to settle water rights. Based on the baseline scenario of the cost-benefit model, the benefits of this system accumulate to $413 million (95% CI $339 million - $508 million) at a 3 percent discount rate, $1,464 (95% CI $1,261 million - $1,776 million) at a 0.1 percent discount rate, and $153 million (95% CI $115 million - $194 million) at a 7 percent discount rate. Costs accumulate to $320 million at a 3 percent discount rate, $632 million at a 0.1 percent discount rate, and $196 million at a 7 percent discount rate. The respective benefit-cost ratio for each discount rate is 1.29, 2.31, and 0.78.
DIGITAL SYSTEM FOR A STATIC ELECTRIC CURRENT METER
Creators: name: Alali, Walid Y
Publisher: name: figshare
Year: 2023
Subjects: Signal processing
Interaction and experience design

description: Abstract: Microelectronic technologie1 made  possible the  im­plementation of solid  1tate  ba1ed metering system1.  In this  paper, an ASIC design  that implements all but the analog part of a watt-hour meter  is described.  This  A­ SIC designed  with the APBB {1} technology  is intented to be used in  conjunction with the  Ferraris  power me­ ter in a hybrid  telecounting system or in a fully static watt-hour meter.  In  the  first  case,  the  data  received and  processed by the  ASJC  is the  disk  turn count  of the Ferraris  power meter, being the transmission  from the latter  to the  ASIC achieved by optical interconnec­tion. In the  second  case,  a fully  static  power meter  is used,  and, data  received  by the  ASIC are two  12  bit words representing the  current  and the  voltage values
Cyclic Integration in the Instrumental Music of Haydn and Mozart
Creators: name: Proksch, Bryan Jeffrey
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Cyclic integration - the manner in which movements of a multi-movement cycle relate to one another - is a compositional device generally associated with music written from the nineteenth century onward, beginning with the works of Beethoven. It is most commonly perceived to be based primarily (if not exclusively) on thematic resemblances. The use of Beethoven's works as a standard for evaluating the practices of other composers, and the limited number of compositions by Haydn and Mozart including thematic resemblances, have combined to create the perception that Haydn and Mozart ignored cyclic integration in the majority of their works. This dissertation argues for a broader conception of cyclic integration in the music of Haydn and Mozart by viewing it as a compositional device that can extend beyond thematic ideas to incorporate a variety of possible elements. These include harmony, texture, form, phrase structure, musical topics, rhythm, articulation, and other musical elements. An analysis of Mozart's String Quartet in A major, K. 464, serves as a case study in demonstrating a methodology for eighteenth-century cyclic integration. A broad survey of their practices from c. 1770-c. 1800 evaluates the extent of their use of cyclic integration as a compositional device. The results of this survey indicate that Haydn and Mozart reserve their strongest connections for symphonies and string quartets, and that their practices changed over the course of time.
Stilgeschichte als Problem. Über die prinzpielle Unmöglichkeit einer digitalen historischen Musikwissenschaft
Creators: name: Nägele, Reiner
Publisher: name: Universität Tübingen
Year: 2017
Subjects: subject: Musikwissenschaft , Digital Humanities , Stilgeschichte , Bayerische Staatsbibliothek , Fachinformationsdienst
subject: 020
subject: 700
subject: 780

description: Im Rahmen des seit 2014 von der DFG geförderten Projektes „Fachinformationsdienst Musikwissenschaft“ an der Bayerischen Staatsbibliothek ist zu beobachten, dass die beratenden Vertreter der systematischen und musikethnologischen Disziplinen von Anbeginn an ein großes Interesse zeigten, dieses aktiv mitzugestalten. Die Musikhistoriker dagegen tun sich bis heute schwer, die DH-spezifischen Förderrichtlinien innovativ fruchtbar zu machen. Die offensichtliche Scheu vor einer konsequent umgesetzten DH-Strategie verweist auf ein grundsätzliches Problem unserer kompositionsgeschichtlich orientierten Disziplin. Eine Abkehr vom Postulat „Kunsterfahrung ist Wahrheitserfahrung“, also ein Bruch mit der hermeneutischen Ontologie, würde nämlich bedeuten, die Historische Musikwissenschaft in ihren Grundfesten zu erschüttern.
DNA Degradation: the Effect of Bluestar® Forensic on Recovered DNA in Various Storage Conditions
Creators: name: Dominici, Ashley
Publisher: name: University of Illinois at Chicago
Year: 2023

description: Luminol is a well-known reagent used at crime scenes for revealing hidden bloodstains, which can then be collected for forensic identification purposes. This study focused on a commercialized luminol solution known as Bluestar® Forensic and attempted to determine its effects on naked DNA in various conditions. DNA was mixed with Bluestar® Forensic and kept in a liquid or dried state at two different temperatures for up to 140 days. DNA was extracted using the organic method and quantified using the Quantifiler™ Trio DNA Quantification Kit. Results showed that storage temperature and time stored were both correlated with differences in recovered DNA from samples, though the trends were not always consistent. Interestingly, the biggest predictor of DNA recovery was state of matter, as DNA was consistently recovered from dried samples but rarely from liquid samples. These results indicate that samples treated with Bluestar® Forensic are best stored in the dried state, though further research is needed to determine optimal storage temperature and time stored for such samples.
DIGITAL SYSTEM FOR A STATIC ELECTRIC CURRENT METER
Creators: name: Alali, Walid Y
Publisher: name: figshare
Year: 2022
Subjects: Signal processing
Interaction and experience design

description: Abstract: Microelectronic technologie1 made  possible the  im­plementation of solid  1tate  ba1ed metering system1.  In this  paper, an ASIC design  that implements all but the analog part of a watt-hour meter  is described.  This  A­ SIC designed  with the APBB {1} technology  is intented to be used in  conjunction with the  Ferraris  power me­ ter in a hybrid  telecounting system or in a fully static watt-hour meter.  In  the  first  case,  the  data  received and  processed by the  ASJC  is the  disk  turn count  of the Ferraris  power meter, being the transmission  from the latter  to the  ASIC achieved by optical interconnec­tion. In the  second  case,  a fully  static  power meter  is used,  and, data  received  by the  ASIC are two  12  bit words representing the  current  and the  voltage values
Hamiltonian Truncation Study of the Phi^4 Theory in Two Dimensions II. The Z_2-Broken Phase and the Chang Duality
Creators: name: Rychkov, Slava
name: Vitale, Lorenzo G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: The Fock-space Hamiltonian truncation method is developed further, paying particular attention to the treatment of the scalar field zero mode. This is applied to the two-dimensional Phi^4 theory in the phase where the Z_2-symmetry is spontaneously broken, complementing our earlier study of the Z_2-invariant phase and of the critical point. We also check numerically the weak/strong duality of this theory discussed long ago by Chang.
description: 28 pages, 28 figures; V2: refs added, published version; V3: added note in Appendix on perturbation theory checks
Eigenvectors of the critical 1-dimensional random Schroedinger operator
Creators: name: Rifkind, Ben
name: Virag, Balint
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: The purpose of this paper is to understand in more detail the shape of the eigenvectors of the random Schroedinger operator H = Delta+V. Here Delta is the discrete Laplacian and V is a random potential. It is well known that under certain assumptions on V the spectrum of this operator is pure point and its eigenvectors are exponentially localized; a phenomenon known as Anderson Localization. We restrict the operator to Z_n and consider the critical model H_n. We show that the shape of a uniformly chosen eigenvector of H_n converges in law to exp (-|t|/4 + Z_t/sqrt(2)), where Z is two-sided Brownian motion.
Digital Power for RMS & PF Meter Based on Microprocessor
Creators: name: Alali, Walid Y
Publisher: name: figshare
Year: 2023
Subjects: Interaction and experience design
Software engineering not elsewhere classified
Engineering design

description: https://figshare.com/articles/journal_contribution/Digital_Power_for_RMS_PF_Meter_Using_Microprocessor/20218160
MPEC 2023-Q55 : 2023 QN1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 QN1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Lagrangian data assimilation into layered ocean model
Creators: name: Liu, Liyan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Since much surface ocean data is Lagrangian in nature, its assimilation into ocean models is a key element of an ocean forecasting system. We investigate the propagation of information vertically caused by the existing vertical correlations between a stack of layers in the water column, such as the Eulerian velocity field and other dynamical variables, by observing Lagrangian data in the surface. We test the method by using different layered models with the known Lagrangian observations at discrete time intervals in the surface layer and unknown sub-surface layers. We adopt the method for assimilating Lagrangian data in which the model is augmented with drifter advection equations and track the correlations between the flow and the drifters via the Kalman Filter. The experiments show that Lagrangian data assimilation is feasible and effective for layered models. The technique is first tested on a two layer point vortex flow: a two layer point vortex system of (N(1) v ;N(2) v ) vortices at each layer with a Gaussian white noise term is modeled by its deterministic counterpart. Positions of N(1) d drifter particles in the top layer are observed at regular time intervals and assimilated into the model. Numerical experiments demonstrate successful system tracking for (N(1) v ;N(2) v ;N(1) d ;N(2) d ) = (2; 2; 1; 0). Our numerical model simulations show that our method is capable of successful tracking of the vortices in both of the layers by observing the Lagrangian data from the top layer. It demonstrates that we can capture the Eulerian velocity field of the point vortex flow in the sub-surface layer by assimilating the Lagrangian data in the top layer. The method we have developed gives an understanding of the potential of Lagrangian data assimilation in models with vertical variation. We further test the method on the two and a half layer reduced gravity shallow water double gyre unsteady flow configuration. Our numerical simulations show that the method is capable of correcting both of the active layers even if Lagrangian observations are only available in the top active layer and the assimilation time interval is of the order of the Lagrangian auto-correction time scale of the flow. The results clearly demonstrate that our method is effective when dealing with a more complex dynamics flow with an unknown sub-surface flow structure. The Lagrangian data assimilation method that we have developed, therefore, provides an approach that allows us to fully realize the potential of Lagrangian data for assimilation in more realistic ocean models.
Active spanning trees with bending energy on planar maps and SLE-decorated Liouville quantum gravity for $κ> 8$
Creators: name: Gwynne, Ewain
name: Kassel, Adrien
name: Miller, Jason
name: Wilson, David B.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We introduce a two-parameter family of probability measures on spanning trees of a planar map. One of the parameters controls the activity of the spanning tree and the other is a measure of its bending energy. When the bending parameter is 1, we recover the active spanning tree model, which is closely related to the critical Fortuin--Kasteleyn model. A random planar map decorated by a spanning tree sampled from our model can be encoded by means of a generalized version of Sheffield's hamburger-cheeseburger bijection. Using this encoding, we prove that for a range of parameter values (including the ones corresponding to maps decorated by an active spanning tree), the infinite-volume limit of spanning-tree-decorated planar maps sampled from our model converges in the peanosphere sense, upon rescaling, to an SLE$_κ$-decorated $γ$-Liouville quantum cone with $κ> 8$ and $γ= 4/\sqrtκ\in (0,\sqrt 2)$.
description: 55 pages, 9 figures; revised
Digital Power for RMS & PF Meter Based on Microprocessor
Creators: name: Alali, Walid Y
Publisher: name: figshare
Year: 2022
Subjects: Interaction and experience design
Software engineering not elsewhere classified
Engineering design

description: This paper represents a sampling digital technique for the power, rms and power­ factor values measurement. It is based on a microcomputer-controlled measure­ ment system. The measurement technique involves taking simultaneous samples at equal time-intervals through the period of both the input voltage and current signals. The required measurement value will be measured by computation from the numerical values of simultaneous input voltage and current samples. The system accuracy quoted is of ±0·05% class. The output result is provided to 5 decimal digits on a display unit, with a lead-tag indication.
Accounting Quality, Corporate Acquisition, and Financing Decisions
Creators: name: Kim, Sangwan
Publisher: name: University of North Carolina at Chapel Hill
Year: 2013

description: This paper examines the extent to which the quality of financial accounting information disciplines manager interests to align with stockholder interests in corporate acquisition and financing decisions. I find that, after controlling for financing constraints, recent performance and payout policy, the tendency of firm managers to time the market is significantly constrained for firms with high-quality financial accounting information. Further, I find that the disciplining impact of accounting information is mostly driven by firms that bid for acquisitions financed with stock issuance. I also provide corroborating evidence by examining a similar disciplining role of financial accounting information in the seasoned public offering markets. I find no such effect for potential acquisitions financed through cash. The evidence suggests that high-quality accounting information allows stockholders to discipline firm managers that are motivated to take advantage of the misvaluation. Further, the results suggest the effectiveness of accounting information as a control mechanism is pronounced for firms that pursue more value-decreasing investment projects.
Absence of heating in a uniform Fermi gas created by periodic driving
Creators: name: Shkedrov, Constantine
name: Menashes, Meny
name: Ness, Gal
name: Vainbaum, Anastasiya
name: Altman, Ehud
name: Sagi, Yoav
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Ultracold atomic gas provides a useful tool to explore many-body physics. One of the recent additions to this experimental toolbox is the Floquet engineering, where periodic modulation of the Hamiltonian allows the creation of effective potentials that do not exist otherwise. When subject to external modulations, however, generic interacting many-body systems absorb energy, thus posing a heating problem that may impair the usefulness of this method. For discrete systems with bounded local energy, an exponentially suppressed heating rate with the driving frequency has been observed previously, leaving the system in a prethermal state for exceedingly long durations. But for systems in continuous space, the situation remains unclear. Here we show that Floquet engineering can be employed to a strongly interacting degenerate Fermi gas held in a flat box-like potential without inducing excessive heating on experimentally relevant timescales. The driving eliminates the effect of a spin-dependent potential originating from a simultaneous magnetic levitation of two different spin states. We calculate the heating rate and obtain a power-law suppression with the drive frequency. To further test the many-body behavior of the driven gas, we measure both the pair-condensation fraction at unitarity and the contact parameter across the BEC-BCS crossover. At low driving frequencies, the condensate fraction is reduced by the time-dependent force, but at higher frequencies, it revives and attains an even higher value than without driving. Our results are promising for future exploration of exotic many-body phases of a bulk strongly-interacting Fermi gas with dynamically engineered Hamiltonians.
description: 16 pages, 10 figures