cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 4 of Comparison and development of a metagenomic next-generation sequencing protocol for combined detection of DNA and RNA pathogens in cerebrospinal fluid
Creators: name: Jiang, Hanfang
name: Xing, Zhihao
name: Liu, Xiaorong
name: Chai, Qiang
name: Xin, Zefeng
name: Zhu, Chunqing
name: Lin, Ruihong
name: Deng, Xuwen
name: Cui, Dong
name: Gao, HongDan
name: Ma, Dongli
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics

description: Additional file 4: Fig. S1. The microbial reads percentage of EBV samples and EV71 samples. A. The microbial reads percentage of EBV samples in methods Total DNA , Total NA ,Total RNA and WTA. B. The microbial reads percentage of EV71 samples in methods Total NA ,Total RNA and WTA. Fig. S2. NR, RPMratio and Coverage percent of target pathogens. Subfigure A/B/C shows NR/ RPMratio/coverage percentage of E. coli respectively comparing four sample pretreatment/nuclear acid extraction methods including Microbial DNA, Total DNA, Total NA and Total RNA. The red dots represent concentration of 106cfu/ml and the blue dots represent concentration of 5x104 cfu/ml. Subfigure D/E/F shows NR/ RPMratio/coverage percentage of SP comparing four sample pretreatment/nuclear acid extraction methods respectively. The red dots represent concentration of 106cfu/ml and the blue dots represent concentration of 5x104 cfu/ml. Subfigure G/H/I shows NR/RPMratio/coverage percentage of EBV respectively comparing four sample pretreatment/nuclear acid extraction methods including Total DNA, Total NA, Total RNA and WTA. The red dots represent concentration of 5x105 copies/ml and the blue dots represent concentration of 5x103 copies/ml. Subfigure J/K/L shows NR/RPMratio/coverage percentage of EV71 respectively comparing four sample pretreatment/nuclear acid extraction methods respectively. The red dots represent concentration of 5x105 copies/ml and the blue dots represent concentration of 5x103 copies/ml. Fig. S3. Genomic coverage of pathogens in CSF from encephalitis patients. A. Genomic coverage of Echovirus 30 in clinical CSF 0006. B. Genomic coverage of coxsackievirus B5 in clinical CSF 0010. Fig. S4. Genomic coverage of Streptococcus pneumoniae, Streptococcus thermophilus and Mogibacterium diversum in sample Microbial DNA-ILL -1. A. Genomic coverage of Streptococcus pneumoniae. B. Genomic coverage of Streptococcus thermophilus. C. Genomic coverage of Mogibacterium diversum.
Additional file 7 of Healthcare system resilience in Bangladesh and Haiti in times of global changes (climate-related events, migration and Covid-19): an interdisciplinary mixed method research protocol
Creators: name: Clech, Lucie
name: Meister, Sofia
name: Belloiseau, Maeva
name: Benmarhnia, Tarik
name: Bonnet, Emmanuel
name: Casseus, Alain
name: Cloos, Patrick
name: Dagenais, Christian
name: De Allegri, Manuela
name: du Loû, Annabel Desgrées
name: Franceschin, Lucas
name: Goudet, Jean-Marc
name: Henrys, Daniel
name: Mathon, Dominique
name: Matin, Mowtushi
name: Queuille, Ludovic
name: Sarker, Malabika
name: Turenne, Charlotte Paillard
name: Ridde, Valéry
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 7.
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0193
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0193, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0193, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Additional file 1 of Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
Creators: name: Sarnella, Annachiara
name: Ferrara, Ylenia
name: Auletta, Luigi
name: Albanese, Sandra
name: Cerchia, Laura
name: Alterio, Vincenzo
name: De Simone, Giuseppina
name: Supuran, Claudiu T.
name: Zannetti, Antonella
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Additional file 1.
Elektronisches Patientendossier: Aktuelle Probleme, Potenziale und wie die Institutionen damit umgehen. Bei Healthcare-Expert:innen nachgefragt
Creators: name: Dettwiler, Raymond
name: Märke, Stefan
Publisher: name: Hochschule für Wirtschaft FHNW, Institute for Competitiveness and Communication
Year: 2022
Subjects: subject: Elektronisches Patientendossier
subject: Gesundheitswesen
subject: Digitalisierung
subject: Digitale Transformation
subject: Digitale Gesundheitskompetenz
subject: Patient:innen
subject: Digital Health
subject: 330 - Wirtschaft

description: Obwohl sich alle Beteiligten ein digitaleres Gesundheitswesen wünschen, ist die Einführung des Elektronischen Patientendossiers (EPD) in der Schweiz bisher keine Erfolgsgeschichte. Um herauszufinden, was die Gründe für diese Situation sind, führten die Autoren Interviews mit sechs verschiedenen Expert:innen aus unterschiedlichen Organisationen, die mit dem EPD tun haben (Spitäler unterschiedlicher Grössen, Arztpraxis, EPD-Anbieter). Die genannten Gründe wurden in einer Onlineumfrage von weiteren Expert:innen validiert und ergänzt. Daraus ergab sich ein deutliches Gesamtbild.
title: Putting the Chemistry Back into Analytical Chemistry
Creators: name: Tyson, Julian
Publisher: name: University of Massachusetts Amherst
Year: 1992
Subjects: subject: Chemistry
subject: Analytical Chemistry
subject: FOS: Chemical sciences

description: Aspects of the current status of and research in analytical chemistry are briefly discussed and the need for cost effective analytical procedures is emphasized. The present and future of a number of aspects of flow-injection analysis are considered. These include the basic theory, the kinetic features, the control features, time-based methodology, and the coupling of sample pretreatment with instrumentation. Several aspects of this latter topic are considered with particular reference to the flow-injection atomic spectrometry combination. Problems of kinetic mismatch between chemistry, manifold residence, and instrument operation are discussed and some possible solutions proposed including the use of closed loop manifolds.
Control Modelling of Cognitive Response States and Predicting with Emoticons on Optical Stimulus for Optimized Affect State.
Creators: name: Isiaka, Fatima
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460201
subject: Artificial life and complex adaptive systems
classificationCode: 460202
subject: Autonomous agents and multiagent systems
classificationCode: 460205
subject: Intelligent robotics
classificationCode: 460207
subject: Modelling and simulation
classificationCode: 460802
subject: Affective computing
classificationCode: 460806
subject: Human-computer interaction

description: A dynamic control model is based on a mathematical representation of the dynamics that exist between the inputs and the outputs of an active system. In terms of the physical representation of physiological responses such as skin conductance response, pupil dilation, and emotion recognition, this can be represented in the form of physiological control systems where the reactions of a natural phenomenon are represented as the mechanical interaction between a person and the object of interest, for this case the optical stimulus as a business webpage. This paper aims to highlight more on the representation of the cognitive response of users as emoticons conveyed to optical stimulus based on dynamic control optimization of a minimization problem. The input parameter includes eye movements with recorded pupil dilation and mouse clicks that correlate to gaze points or fixation location. The model is represented as a window-based dynamic control with a set module for each interphase that predicts the users’ cognitive response to the optical visual display as emotive emoticons for precognitive analysis. The output shows users expressed more neutral responses than either stressed or relaxed moods to the product they viewed online.
Improving teaching, teamwork, and school organization. Collaboration networks in school teams
Creators: name: Wullschleger, Andrea
name: Vörös, András
name: Rechsteiner, Beat
name: Rickenbacher, Ariane
name: Maag Merki, Katharina
Publisher: name: Elsevier
Year: 2023
Subjects: subject: Teacher collaboration
subject: School improvement
subject: Social network analysis
subject: Exponential random graph model (ERGM)
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Whereas previous studies on teacher collaboration have focused almost exclusively on improving teaching, this paper investigates collaboration in three highly important school improvement areas. Data for three collaboration networks were collected in four secondary schools in Switzerland in 2018 on teachers exploring new ideas on teaching (teaching improvement), teamwork (team improvement), and school organization (organizational improvement). Using social network analysis, we examined to what extent the collaboration networks overlap, how network structures differ, and what factors explain these differences. The results revealed substantial differences between collaboration in the three areas. This suggests that future research should examine collaboration from a multidimensional network perspective.
Additional file 1 of Assessing the utility and efficacy of e-OSCE among undergraduate medical students during the COVID-19 pandemic
Creators: name: Shorbagi, Sarra
name: Sulaiman, Nabil
name: Hasswan, Ahmad
name: Kaouas, Mujtaba
name: Al-Dijani, Mona M.
name: El-hussein, Rania Adil
name: Daghistani, Mada Talal
name: Nugud, Shumoos
name: Guraya, Salman Yousuf
Publisher: name: figshare
Year: 2022
Subjects: subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Hematology

description: Additional file 1: Appendix 1. Blueprint of end of clerkship e-OSCE stations. Appendix 2. Questionnaire used for the students’ evaluation of e-OSCE. Appendix 3. Questionnaire used for the examiners’ evaluation of e-OSCE. Appendix 4. Questionnaire used for the e-OSCE team’s evaluation of e-OSCE.
title: 03_0858
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Development and field validation of a community-engaged particulate matter air quality monitoring network in Imperial, California
Creators: name: Carvlin, Graeme N.
name: Lugo, Humberto
name: Olmedo, Luis
name: Bejarano, Ester
name: Wilkie, Alexa
name: Meltzer, Dan
name: Wong, Michelle
name: King, Galatea
name: Northcross, Amanda
name: Jerrett, Michael
name: English, Paul B.
name: Hammond, Donald
name: Seto, Edmund
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: The Imperial County Community Air Monitoring Network was developed as part of a community-engaged research study to provide real-time particulate matter (PM) air quality information at a high spatial resolution in Imperial County, California. The network augmented the few existing regulatory monitors and increased monitoring near susceptible populations. Monitors were both calibrated and field validated, a key component of evaluating the quality of the data produced by the community monitoring network. This paper examines the performance of a customized version of the low-cost Dylos optical particle counter used in the community air monitors compared with both PM2.5 and PM10 (particulate matter with aerodynamic diameters <2.5 and <10 μm, respectively) federal equivalent method (FEM) beta-attenuation monitors (BAMs) and federal reference method (FRM) gravimetric filters at a collocation site in the study area. A conversion equation was developed that estimates particle mass concentrations from the native Dylos particle counts, taking into account relative humidity. The R2 for converted hourly averaged Dylos mass measurements versus a PM2.5 BAM was 0.79 and that versus a PM10 BAM was 0.78. The performance of the conversion equation was evaluated at six other sites with collocated PM2.5 environmental beta-attenuation monitors (EBAMs) located throughout Imperial County. The agreement of the Dylos with the EBAMs was moderate to high (R2 = 0.35–0.81). Implications: The performance of low-cost air quality sensors in community networks is currently not well documented. This paper provides a methodology for quantifying the performance of a next-generation Dylos PM sensor used in the Imperial County Community Air Monitoring Network. This air quality network provides data at a much finer spatial and temporal resolution than has previously been possible with government monitoring efforts. Once calibrated and validated, these high-resolution data may provide more information on susceptible populations, assist in the identification of air pollution hotspots, and increase community awareness of air pollution.
Membrane potentials of cancer cells.pdf
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2018
Subjects: subject: Cancer
subject: Cell Biology
subject: 60103 Cell Development, Proliferation and Death
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 60110 Receptors and Membrane Biology
subject: 60104 Cell Metabolism
subject: 111201 Cancer Cell Biology
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
subject: 110709 Tumour Immunology

description: We discuss why the membrane potentials of cancer cells are often smaller than those of healthy cells, and why the stresses associated with reduced membrane potentials might not automatically cause destruction of cells by apoptosis.
The fact that cytochrome c appears as a key intermediary both in cellular respiration and in apoptosis suggests that damage to cytochrome c, or failure to express it, might reduce ion pumping across the cell membrane, thus diminishing the cellular membrane potential, whilst simultaneously damaging a key apoptosis pathway. Degraded respiration will also force the cell to obtain energy from glycolysis, consistent with the Warburg Hypothesis.
Deletion of functionality provided by mitochondria, such as respiration and apoptosis, would cause eukaryotic cells to behave in some ways like their distant ancestors, before they incorporated mitochondria.
The time that elapses between, on the one hand, the initial damage and reduction in membrane potential and, on the other hand, the onset of cancer allows a pre-emptive strike against misbehaving cells before they become cancerous. The modified electrical properties of impaired cells could function as targets for specially chosen or engineered species of immune system cells. E.g., it may be possible to decorate the surfaces of the damaged cells with molecules that first attach preferentially to cells with low membrane potentials, then attract and activate macrophages that will consume the errant cells and initiate a wider immune response. Immune cells that are attracted towards electrical targets, instead of relying entirely on structural motifs, are less likely to be affected by structural mutations of target cells.
Track 2 Paper: The Future of Metadata-Oriented Testing of Research Software: Automated Generation of Test Regimes and Other Benefits
Creators: name: Mulholland, Doug
name: Alencar, Paulo
name: Cowan, Don
Publisher: name: figshare
Year: 2017
Subjects: subject: Computer Software
subject: FOS: Computer and information sciences

description: Software systems and applications that make greater use of descriptive data ("metadata") and less use of program code can, in general, be maintained by individuals with less knowledge of technology and are more readily tested by automated regimes with automatically generated test suites.
Membrane potentials of cancer cells.pdf
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2017
Subjects: subject: Cancer
subject: Cell Biology
subject: 60103 Cell Development, Proliferation and Death
subject: FOS: Biological sciences

description: We discuss why the membrane potentials of cancer cells are often smaller than those of healthy cells, and why the stresses associated with reduced membrane potentials might not automatically cause destruction of cells by apoptosis.
The fact that cytochrome c appears as a key intermediary both in cellular respiration and in apoptosis suggests that damage to cytochrome c, or failure to express it, might reduce ion pumping across the cell membrane, thus diminishing the cellular membrane potential, whilst simultaneously damaging a key apoptosis pathway. Degraded respiration will also force the cell to obtain energy from glycolysis, consistent with the Warburg Hypothesis.
Forschungsverständnis pädagogischer Hochschulen - ein Diskussionsbeitrag
Creators: name: Beywl, Wolfgang
name: Künzli, Christine
name: Messmer, Roland
name: Streit, Christine
Publisher: name: Schweizerische Gesellschaft für Lehrerinnen- und Lehrerbildung
Year: 2015
Subjects: subject: Pädagogische Hochschule Bildungsforschung Erziehungswissenschaft Angewandte Forschung Grundlagenforschung
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Der Artikel geht der Frage nach, wie Pädagogische Hochschulen angesichts ihrer spezifischen Situierung in den Systemen von Bildungswissenschaft und -praxis ihre Forschung verorten und daran anknüpfend Forschungsstrategien entwickeln können. Basierend auf vorliegenden Ordnungsversuchen wird ein durch zwei Dimensionen – Art des angestrebten Nutzens und sozialer Produktionsmodus – strukturiertes Ordnungsschema (Viererfeld der Forschung) beschrieben und beispielhaft veranschaulicht. Abschliessend wird für eine Profilierung plädiert, welche auf instrumentellen Nutzen für die Praxis ausgerichtete Forschung deutlich ausweist, und bei Erhalt der Differenz Wissenschaft-Praxis die Austauschbeziehungen mit den Praxisakteuren auch innerhalb des Forschungsprozesses selbst systematisch stärkt. Mit dem Beitrag soll ein Diskurs über längerfristig ausgerichtete Forschungsperspektiven der Pädagogischen Hochschulen angeregt werden, der sich den Anforderungen nach Anschlussfähigkeit in der internationalen Scientific Community sowie nach Nützlichkeit für nationale, regionale und lokale Bildungssysteme stellt.
title: ADCO, Cartulaire de Saint-Etienne de Dijon (XIIIe siècle), Cart. 34 (G 138), 22 folios, f. 0027
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Saint-Etienne de Dijon (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 34 (G 138), 22 folios, f. 0027, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Saint-Etienne de Dijon (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 34 (G 138), 22 folios, f. 0027, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Additional file 1 of Combined miRNA and SERS urine liquid biopsy for the point-of-care diagnosis and molecular stratification of bladder cancer
Creators: name: Moisoiu, Tudor
name: Dragomir, Mihnea P.
name: Iancu, Stefania D.
name: Schallenberg, Simon
name: Birolo, Giovanni
name: Ferrero, Giulio
name: Burghelea, Dan
name: Stefancu, Andrei
name: Cozan, Ramona G.
name: Licarete, Emilia
name: Allione, Alessandra
name: Matullo, Giuseppe
name: Iacob, Gheorghita
name: Bálint, Zoltán
name: Badea, Radu I.
name: Naccarati, Alessio
name: Horst, David
name: Pardini, Barbara
name: Leopold, Nicolae
name: Elec, Florin
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1: Figure S1. Differentially expressed miRNAs in urine of patients with bladder cancer (BC) and controls (CTRL) (prospective cohort). A Volcano plot showing the differentially expressed urine miRNAs between BC patients and CTRLs in the NGS analysis. The color intensity of the dots represents the expression level (as the log10 of the normalized mean counts), the x-axis represents the fold change, and the y-axis the nominal p-value. B Dot plot showing the statistical significance of the functional terms identified as enriched in the target genes of differentially expressed miRNAs between BC cases and controls. The size of the dot is proportional to the number of target genes belonging to each term, while the color code refers to the coefficient computed by RBiomirGS. Negative (in blue) and positive (in red) coefficients represent processes predicted to be, respectively, downregulated or upregulated based on the miRNA expression change between the two groups. C The expression of the three candidate miRNAs analyzed by RT-qPCR. The expression was normalized with the mean of 7 miRNAs used for this study. Mean ± SD. *p
80 colour pencils
Creators: name: Ritzmann, Marion
Publisher: name: edition fink
Year: 2015
Subjects: 80 colour pencils
Fortsetzung folgt
edition fink
Georg Rutishauser
Claudiabasel
Marion Ritzmann

description: Published as part of “Fortsetzung folgt” / 80 full-page illustration in colour, pad binding The artist’s pad “80 colour pencils” by Marion Ritzmann is published as part of the series “Fortsetzung folgt” (to be continued), an open sequence of individual publications, which are connected and contextualized through the artist’s website as an integral part of the project. The starting point for “80 colour pencils” is a box of eighty crayons in different colours and the concept of painting an A4 sheet of paper completely with each of them, resulting in eighty monochrome drawings. For the publication, these were facsimiled and glued into a pad as a colour fan. A bit-link on the cover page takes us to the corresponding entry on the artist's website, where we find further documentary visual material and a description of the work.
Membrane potentials of cancer cells.pdf
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2018
Subjects: subject: Cancer
subject: Cell Biology
subject: 60103 Cell Development, Proliferation and Death
subject: FOS: Biological sciences

description: We discuss why the membrane potentials of cancer cells are often smaller than those of healthy cells, and why the stresses associated with reduced membrane potentials might not automatically cause destruction of cells by apoptosis.
The fact that cytochrome c appears as a key intermediary both in cellular respiration and in apoptosis suggests that damage to cytochrome c, or failure to express it, might reduce ion pumping across the cell membrane, thus diminishing the cellular membrane potential, whilst simultaneously damaging a key apoptosis pathway. Degraded respiration will also force the cell to obtain energy from glycolysis, consistent with the Warburg Hypothesis.
The time that elapses between, on the one hand, the initial damage and reduction in membrane potential and, on the other hand, the onset of cancer allows a pre-emptive strike against the misbehaving cell before it becomes cancerous. It may be possible to, e.g., decorate the surfaces of the damaged cells with molecules that first attach preferentially to cells with low membrane potentials, then attract and activate macrophages that will consume the errant cells and initiate a wider immune response.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Cart. 185 (11 H 70), f. 0154v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0154v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome I, Archives départementales de la Côte-d'Or, Cart. 185 (11 H 70), f. 0154v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Development of immediate release 3D-printed dosage forms for a poorly water-soluble drug by fused deposition modeling. Study of morphology, solid state and dissolution
Creators: name: Imanidis, Georgios
name: Fanous, Marina
name: Bitar, Malak
name: Gold, Sarah
name: Sobczuk, Adam
name: Hirsch, Adam
name: Ogorka, Joerg
Publisher: name: Elsevier
Year: 2021
Subjects: 3D-printing
Tablet Immediate release
Poorly soluble drug
X-ray computer microtomography
Personalized dosage form
BCS class IV drug

description: 3D-printing technologies such as Fused Deposition Modeling (FDM) bring a unique opportunity for personalized and flexible near-patient production of pharmaceuticals, potentially improving safety and efficacy for some medications. However, FDM-printed tablets often exhibit tendency for slow dissolution due to polymer erosion-based dissolution mechanisms. Development of immediate release (IR) 3D-printed dosage with poorly water-soluble compounds is even more challenging but necessary to ensure wide applicability of the technology within pharmaceutical development portfolios. In this work, process and morphology were considered to achieve IR of BCS class IV compound lumefantrine as model active pharmaceutical ingredient (API) using basic butylated methacrylate copolymer (Eudragit EPO) as matrix former, as well as hydrophilic plasticizer xylitol and pore former maltodextrin. Grid-designed tablets with size acceptable for children from 6 years old and varying programmed infill density were successfully 3D-printed with 5% lumefantrine while higher drug load led to increased brittleness which is incompatible with 3D-printing. Lumefantrine assay was 92 to 97.5% of theoretical content depending on drug load and process parameters. 3D-printed tablets with 65% infill density met rapid release criteria, while 80% and 100% showed slower dissolution. Structural characteristics of 3D-printed tablets with non-continuous surface such as accessible porosity and specific surface area by weight and by volume were quantified by a non-destructive automated µCT-based methodology and were found to correlate with dissolution rate. Increase in accessible porosity, total surface area, specific surface area and decrease in relative density were statistically significant critical factors for modification of lumefantrine dissolution rate. Crystallinity in manufactured tablets and filaments was explored by highly sensitive Raman mapping technique. Lumefantrine was present in the fully amorphous state in the tablets exhibiting adequate stability for on-site manufacturing. The study demonstrates feasibility of immediate release FDM-3D-printed tablets with BCS class IV API and illustrates the correlation of FDM design parameters with morphological and dissolution characteristics of manufactured tablets.
Comprehensive characterisation of tribo-layer in a Cu-15Ni-8Sn alloy during dry sliding wear
Creators: name: Li, Daoxi
name: Wang, Zhi
name: Zhao, Chao
name: Luo, Zongqiang
name: Yang, Chao
name: Zhang, Weiwen
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: The detailed characteristic of the tribo-layer in an age-hardening Cu-15Ni-8Sn alloy was studied with advanced analysis techniques. A comprehensive picture of the tribo-layer was drawn from nanoscale to macroscale. The characterisation was done for the oxide layer (OL) that is easy to scaling off during the preparation of metallographic samples, showing a homogeneous mixture of oxide and nanocrystalline particles with a thickness of several micrometers. The mechanically mixed layer (MML) is a multi-layer structure. In addition, the spinodal structure and ordered intermetallic precipitates existing in the matrix were gradually transformed or disappeared in OL and MML. Furthermore, there is a nanocrystalline transformation on the top of plastically deformed layer (PDL), where thin twin-matrix lamellar structure and equiaxed nanocrystallines were formed.
Membrane potentials of cancer cells.pdf
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2018
Subjects: subject: Cancer
subject: Cell Biology
subject: 60103 Cell Development, Proliferation and Death
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 60110 Receptors and Membrane Biology
subject: 60104 Cell Metabolism
subject: 111201 Cancer Cell Biology
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
subject: 110709 Tumour Immunology

description: We discuss why the membrane potentials of cancer cells are often smaller than those of healthy cells, and why the stresses associated with reduced membrane potentials might not automatically cause destruction of cells by apoptosis.
The fact that cytochrome c appears as a key intermediary both in cellular respiration and in apoptosis suggests that damage to cytochrome c, or failure to express it, might reduce ion pumping across the cell membrane, thus diminishing the cellular membrane potential, whilst simultaneously damaging a key apoptosis pathway. Degraded respiration will also force the cell to obtain energy from glycolysis, consistent with the Warburg Hypothesis.
The time that elapses between, on the one hand, the initial damage and reduction in membrane potential and, on the other hand, the onset of cancer allows a pre-emptive strike against misbehaving cells before they become cancerous. The modified electrical properties of impaired cells could function as targets for specially chosen or engineered species of immune system cells. E.g., it may be possible to decorate the surfaces of the damaged cells with molecules that first attach preferentially to cells with low membrane potentials, then attract and activate macrophages that will consume the errant cells and initiate a wider immune response. Immune cells that are attracted towards electrical targets, instead of relying entirely on structural motifs, are less likely to be affected by structural mutations of target cells.
Additional file 1 of Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors
Creators: name: Heynen, Guus J. J. E.
name: Lisek, Kamil
name: Vogel, Regina
name: Wulf-Goldenberg, Annika
name: Alcaniz, Joshua
name: Montaudon, Elodie
name: Marangoni, Elisabetta
name: Birchmeier, Walter
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: 60506 Virology

description: Additional file 1. Figures S1-S5 and Table S1.
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00490
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00490, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Mechanistic, energetic and structural studies of carbon nanotubes functionalised with dihydroartemisinin drug in gas and solution phases
Creators: name: Naderi, Sahar
name: Morsali, Ali
name: Bozorgmehr, Mohammad Reza
name: S. Ali Beyramabadi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: In this work, using density functional theory, the molecular mechanism of noncovalent interactions of drug dihydroartemisinin (DHA) with (5, 5) pristine (NT) and COOH- functionalised carbon nanotube (NTCOOH) and two mechanisms of covalent functionalisation of this drug with NTCOOH and COCl- functionalised carbon nanotube (NTCOCl) have been studied. Quantum molecular descriptors for five (DHA/NT1-5) and three (DHA/NTCOOH1-3) configurations of noncovalent interaction were calculated. It was specified that binding of DHA with pristine and COOH functionalised CNT is thermodynamically favourable. Using NTCOOH is more desirable due to a stronger interaction between the DHA and carbon nanotube and higher solubility. DHA can bond to NTCOOH via hydroxyl group. The reaction of DHA with NTCOCl has activation energy lower than NTCOOH, being the reason for suitability of NTCOCl for covalent functionalisation of DHA onto carbon nanotubes. These results could be generalised to other similar drugs.
Gifts 101: A Systematic Approach for Gifts of Music
Creators: name: Heath, Kristin
name: Merkey, Terra
Publisher: name: Carnegie Mellon University
Year: 2017
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Making decisions about gift donations to the library can be overwhelming when you accept your first professional music librarian job. The authors provide insight into their academic institutions and offer practical advice based on personal experience and a review of the literature. The goal is to help newer music librarians explore ideas and documents they can implement at their institutions, and give more experienced librarians an opportunity to revisit their gifts policies and procedures.
Charleston Hyde Park Debate 2017 Opening Statement
Creators: name: Rouhi, Sara
Publisher: name: figshare
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Economics
subject: 140199 Economic Theory not elsewhere classified
subject: FOS: Economics and business

description: Charleston Conference Hyde Park Debate
Resolved: The journal impact factor does more harm than good.Moderated by Rick Anderson, Associate Dean for Collections & Scholarly Communication, University of UtahIn Favor: Sara Rouhi, Director of Business Development, North America, at AltmetricAgainst: Ann Beynon, Manager, Solution Specialists, North America, at Clarivate AnalyticsDoes the journal impact factor cause more harm than good? Come hear the arguments for and against it as the popular debate session from the annual Charleston Library Conference makes its online debut!
The debate will be conducted in general accordance with Oxford Union rules. All in the audience will vote their opinion on the resolution before the debate begins and the vote totals will be recorded. Each speaker will offer a formal opening statement, followed by a response to the other’s statement, and then we’ll open the floor to discussion by taking questions from the audience.
At the conclusion of the debate, another vote will be taken. The winner of the debate is the one who causes the most audience members to change their votes.
Coral reefs in the Southern Barents Sea: habitat description and the effects of bottom fishing
Creators: name: Buhl-Mortensen, Pål
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Fifteen Lophelia reefs from offshore to coastal areas off northern Norway were studied using video. Health status of the coral habitat (degree of physical impact, % cover of living tissue, colony size), occurrence of trawl marks and lost fishing gear, height of coral colonies and associated fauna were analysed from 44 video-lines. Fishing impact was more frequent on the offshore reefs (36.5% of the observed areas) than those in the coastal reefs (0.6%). The most visible effects of fishing were broken and displaced coral colonies. At some sites only small scattered fragments of live corals were observed, indicating recent impact. The mean colony height of Lophelia and gorgonian corals at impacted sites was around half the size of those at non-impacted sites. Both species richness and abundance was higher at non-impacted coral habitats compared to impacted. The actinarian Protanthea simplex and unidentified brittlestars were the only taxa with higher abundance on impacted compared with non-impacted habitats. The reefs at the offshore location were protected against bottom trawling in 2009 through the establishment of a marine protected area (MPA), but a general ban against trawling on known coral reefs had already been implemented in 1999. In the MPA, signs of regrowth were observed. Most of the observed damage probably occurred over 10 years earlier. Results show that live and non-impacted cold water coral reefs have an important ecological function by enhancing the local biodiversity and fish abundance. Preventing further damage to impacted reefs may lead to full recovery within a few decades.
Additional file 1 of Exploring the economic impact of inappropriate antibiotic use: the case of upper respiratory tract infections in Ghana
Creators: name: Janssen, Jip
name: Afari-Asiedu, Samuel
name: Monnier, Annelie
name: Abdulai, Martha Ali
name: Tawiah, Theresa
name: Wertheim, Heiman
name: Baltussen, Rob
name: Asante, Kwaku Poku
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. CHEERS checklist.
Additional file 1 of Variety and quantity of dietary protein intake from different sources and risk of new-onset diabetes: a Nationwide Cohort Study in China
Creators: name: Zhou, Chun
name: Liu, Chengzhang
name: Zhang, Zhuxian
name: Liu, Mengyi
name: Zhang, Yuanyuan
name: Li, Huan
name: He, Panpan
name: Li, Qinqin
name: Qin, Xianhui
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional File 1: Fig. S1-S2. Fig. S1. Flow chart of study participants. Fig. S2. The longitudinal comparisons of macronutrients intake from 1997-2011. Table S1-S8. Table S1. Personal characteristics of the included and excluded participants. Table S2. Food sources of dietary protein intake. Table S3. Sensitivity analysis of total protein intake (% of energy) with new-onset diabetes. Table S4. Stratified analyses of the association between total protein intake (% of energy) and new-onset diabetes. Table S5. The relations of specific sourced proteins intake (proportion of non-consumers < 20%) with new-onset diabetes. Table S6. The relations of specific sourced proteins intake (proportion of non-consumers ≥ 20%) with new-onset diabetes. Table S7. The sensitivity analysis of association between variety score of protein sources and new-onset diabetes. Table S8. Stratified analyses of the association between variety score of protein sources and new-onset diabetes.
Additional file 1 of The online learning experience and reported headaches associated with screen exposure time among Saudi health sciences students during the COVID-19 pandemic
Creators: name: Abou Hashish, Ebtsam Aly
name: Baatiah, Nada Yasser
name: Bashaweeh, Alia Hamdi
name: Kattan, Abdullah Mohammad
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary Table 1. Demographic and general information of the study subjects (N= 353). Supplementary Table 2. Participant’s perception of online learning experience per items (N= 353). Supplementary Table 3. Challenges experienced with online learning reported by participants (N= 247).