cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A parallel interaction potential approach coupled with the immersed boundary method for fully resolved simulations of deformable interfaces and membranes
Creators: name: Spandan, Vamsi
name: Meschini, Valentina
name: Ostilla-Monico, Rodolfo
name: Lohse, Detlef
name: Querzoli, Giorgio
name: de Tullio, Marco D
name: Verzicco, Roberto
Publisher: name: arXiv
Year: 2016
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In this paper we show and discuss the use of a versatile interaction potential approach coupled with an immersed boundary method to simulate a variety of flows involving deformable bodies. In particular, we focus on two kinds of problems, namely (i) deformation of liquid-liquid interfaces and (ii) flow in the left ventricle of the heart with either a mechanical or a natural valve. Both examples have in common the two-way interaction of the flow with a deformable interface or a membrane. The interaction potential approach (de Tullio & Pascazio, Jou. Comp. Phys., 2016; Tanaka, Wada and Nakamura, Computational Biomechanics, 2016) with minor modifications can be used to capture the deformation dynamics in both classes of problems. We show that the approach can be used to replicate the deformation dynamics of liquid-liquid interfaces through the use of ad-hoc elastic constants. The results from our simulations agree very well with previous studies on the deformation of drops in standard flow configurations such as deforming drop in a shear flow or a cross flow. We show that the same potential approach can also be used to study the flow in the left ventricle of the heart. The flow imposed into the ventricle interacts dynamically with the mitral valve (mechanical or natural) and the ventricle which are simulated using the same model. Results from these simulations are compared with ad- hoc in-house experimental measurements. Finally, a parallelisation scheme is presented, as parallelisation is unavoidable when studying large scale problems involving several thousands of simultaneously deforming bodies on hundreds of distributed memory computing processors.
A new pressure-parametrization unified dark fluid model
Creators: name: Wang, Deng
name: Yan, Yang-Jie
name: Meng, Xin-He
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We propose a new pressure-parametrization model to explain the accelerated expansion of the late-time Universe by considering the dark contents (dark matter and dark energy) as a unified dark fluid. To realize this model more physically, we reconstruct it with the quintessence and phantom scalar fields, respectively. We use the recent cosmological data to constrain this model, distinguish it from the standard cosmological model and find that the value of the Hubble constant $H_0=68.34^{+0.53}_{-0.92}$ supports the global measurement by the Planck satellite at the $1σ$ confidence level.
hnRNPA1 impedes snakehead vesiculovirus replication via competitively disrupting viral phosphoprotein-nucleoprotein interaction and degrading viral phosphoprotein
Creators: name: Liu, An-Qi
name: Qin, Xiangmou
name: Wu, Hui
name: Feng, Hao
name: Zhang, Yong-An
name: Tu, Jiagang
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) plays an important role in regulating the replication of many viruses. However, it remains elusive whether and how hnRNPA1 regulates fish virus replication. In this study, the effects of twelve hnRNPs on the replication of snakehead vesiculovirus (SHVV) were screened. Three hnRNPs, one of which was hnRNPA1, were identified as anti-SHVV factors. Further verification showed that knockdown of hnRNPA1 promoted, while overexpression of hnRNPA1 inhibited, SHVV replication. SHVV infection reduced the expression level of hnRNPA1 and induced the nucleocytoplasmic shuttling of hnRNPA1. Besides, we found that hnRNPA1 interacted with the viral phosphoprotein (P) via its glycine-rich domain, but not with the viral nucleoprotein (N) or large protein (L). The hnRNPA1-P interaction competitively disrupted the viral P-N interaction. Moreover, we found that overexpression of hnRNPA1 enhanced the polyubiquitination of the P protein and degraded it through proteasomal and lysosomal pathways. This study will help understanding the function of hnRNPA1 in the replication of single-stranded negative-sense RNA viruses and providing a novel antiviral target against fish rhabdoviruses.
Additional file 1: Figure S1. of Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study
Creators: name: Hayashi, Tomoyuki
name: Yamashita, Taro
name: Terashima, Takeshi
name: Suda, Tsuyoshi
name: Okada, Hikari
name: Asahina, Yoshiro
name: Hayashi, Takehiro
name: Hara, Yasumasa
name: Nio, Kouki
name: Sunagozaka, Hajime
name: Takatori, Hajime
name: Arai, Kuniaki
name: Sakai, Yoshio
name: Yamashita, Tatsuya
name: Eishiro Mizukoshi
name: Honda, Masao
name: Kaneko, Shuichi
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Kaplan-Meier survival analysis of HCC patients classified as HGF-high and -low, IL-4-high and -low, and SDF1-high and â low in Cohort 2. (PDF 101 kb)
Why has the USA Never Elected a Female President?
Creators: name: Mosashvili, Gia
Publisher: name: figshare
Year: 2020
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 160699 Political Science not elsewhere classified

description: The United States of America is the leader democracy in the world, which supports other countries to protect human rights, build international relations, avoid gender discrimination and achieve high level of development. Surprisingly, a country where more than 50 percent of population is woman, has never elected a female president. This topic constantly draws attention, because from the declaring of the independence to present, Americans always distrusted woman candidate. The first reason is historical inequality between men and women. American history has kept some facts when woman was considered as an extension of her husband and did not need her own vote. Secondly, the level of political ambition between males and females is different. Men and women do not have an equal interest in politics. This is fundamental reason of women’s under-representation in politics. The third reason is strange behavior of Americans during presidential elections. The fourth, beside official, constitutional requirements, many other unofficial requirements exist and there the prospect becomes trickier for a woman candidate. In contrast to the past, today women are more involved in presidential and other political campaigns, but despite this, in most of cases citizens select males anyway. Both parties, Democrats and Republicans claim that their party would get the first woman into the White House.The aim of this paper is to introduce fundamental reasons, why has the USA never elected a female president, when women can perform as well as men in running for office. Primary and secondary documents are analyzed with qualitative research. There are also used official statistics of international organizations (CAWP, IPU). Major research is based on the analysis of the US Constitution.
The Early Evolution of Star Clusters in Compressive and Extensive Tidal Fields
Creators: name: Webb, Jeremy J.
name: Patel, Saahil S.
name: Vesperini, Enrico
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present N-body simulations of star clusters that initially evolve within a strong compressive tidal field and then transition into extensive tidal fields of varying strengths. While subject to compressive tides, clusters can undergo significant heating due to two-body interactions and mass loss due to stellar evolution. When the cluster transitions into an extensive tidal field it is super-virialized, which leads to a rapid expansion and significant mass loss before the cluster reaches virial equilibrium. After the transition, clusters are significantly less massive, more extended and therefore more tidally filling than clusters which have spent their entire lifetime in a similar extensive tidal field.
description: 5 pages, 4 figures, Accepted for publication in MNRAS Letters
Additional file 3: of Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy
Creators: name: KĂźhne, Louisa
name: Jung, Bettina
name: Poth, Helen
name: Schuster, Antonia
name: Wurm, Simone
name: Ruemmele, Petra
name: Banas, Bernhard
name: Bergler, Tobias
Publisher: name: figshare
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: anti-CD11b/c and anti-CD68 FACS costain of rat splenocytes. (A) shows unstained cells, (B) shows anti-CD11b/c-PE antibody only, and (C) shows anti-anti-CD11b/c-PE antibody and anti-CD68-APC antibody co-stain of rat splenocytes. (PDF 82 kb)
Field-induced quantum criticality in the Kitaev system $α$-RuCl$_3$
Creators: name: Wolter, A. U. B.
name: Corredor, L. T.
name: Janssen, L.
name: Nenkov, K.
name: Schönecker, S.
name: Do, S. -H.
name: Choi, K. -Y.
name: Albrecht, R.
name: Hunger, J.
name: Doert, T.
name: Vojta, M.
name: Büchner, B.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: $α$-RuCl$_3$ has attracted enormous attention since it has been proposed as a prime candidate to study fractionalized magnetic excitations akin to Kitaev's honeycomb-lattice spin liquid. We have performed a detailed specific-heat investigation at temperatures down to $0.4$ K in applied magnetic fields up to $9$ T for fields parallel to the $ab$ plane. We find a suppression of the zero-field antiferromagnetic order, together with an increase of the low-temperature specific heat, with increasing field up to $μ_0H_c\approx 6.9$ T. Above $H_c$, the magnetic contribution to the low-temperature specific heat is strongly suppressed, implying the opening of a spin-excitation gap. Our data point toward a field-induced quantum critical point (QCP) at $H_c$; this is supported by universal scaling behavior near $H_c$. Remarkably, the data also reveal the existence of a small characteristic energy scale well below $1$~meV above which the excitation spectrum changes qualitatively. We relate the data to theoretical calculations based on a $J_1$--$K_1$--$Γ_1$--$J_3$ honeycomb model.
description: 5 pages, 4 figures (main text), plus Supplemental Material
Événement d'engagement national de NATI00NS en Tunisie
Creators: name: Khomsi, Mahdi
name: Boutiba Mrad, Jihen
name: Fersi, Cheima
name: Gargouri, Samia
name: Dhahri, Samia
name: MAKI, Abdourahman
name: JELASSI KAMOUN, Emna
name: Attia, Rafla
Publisher: name: Zenodo
Year: 2024

description: Les pressions de dégradation, principalement dues aux activités humaines liées à la surconsommation et aux processus industriels, affectent la santé des sols par des dommages physiques ou l'introduction de polluants. À leur tour, ces processus perturbent la capacité des sols à fournir une série de services écosystémiques, impliquant ainsi des conséquences économiques, environnementales et sociétales majeures; soit 60 à 70 % des sols en Europe sont dans un état malsain. Il est donc urgent de passer à l'action.

L'ambitieuse mission de l'UE "Un pacte pour les sols en Europe" a pour objectif la création de 100 "Living Labs" et "Lighthouses" régionaux, véritables centres de connaissances et d'innovation, capables de créer et de tester, conjointement, des pratiques et des solutions de gestion des sols permettant d'améliorer la santé de ceux-ci.L'ambition de la mission d'obtenir des effets visibles grâce à ses huit objectifs spécifiques rend nécessaire un déploiement régulier et efficace des "Living Labs", ainsi qu'un bon fonctionnement et une capitalisation efficace des résultats. À cet effet, les LL doivent être bien ancrés, sur la base de communautés fortes et engagées, conscientes des besoins spécifiques des sols dans le cadre de la mission et de l'accès aux réseaux de connaissances et d'échange de connaissances.

Sous la coordination de BUSINESSMED et dans le cadre l’évènement d’engagement en Tunisie, le projet NATI00NS assistera et agira en tant que médiateur pour la mission, en adressant les principaux messages de sensibilisation aux parties prenantes nationales.
Radii and Mass-loss Rates of Type IIb Supernova Progenitors
Creators: name: Ouchi, Ryoma
name: Maeda, Keiichi
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Several Type IIb supernovae (SNe IIb) have been extensively studied, both in terms of the progenitor radius and the mass-loss rate in the final centuries before the explosion. While the sample is still limited, evidence has been accumulating that the final mass-loss rate tends to be larger for a more extended progenitor, with the difference exceeding an order of magnitude between the more and less extended progenitors. The high mass-loss rates inferred for the more extended progenitors are not readily explained by a prescription commonly used for a single stellar wind. In this paper, we calculate a grid of binary evolution models. We show that the observational relation in the progenitor radii and mass-loss rates may be a consequence of non-conservative mass transfer in the final phase of progenitor evolution without fine tuning. Further, we find a possible link between SNe IIb and SNe IIn. The binary scenario for SNe IIb inevitably leads to a population of SN progenitors surrounded by dense circumstellar matter (CSM) due to extensive mass loss ($\dot{M} \gtrsim 10^{-4} M_{\odot} \mathrm{yr}^{-1}$) in the binary origin. About 4% of all observed SNe IIn are predicted to have dense CSM, produced by binary non-conservative mass transfer, whose observed characteristics are distinguishable from SNe IIn from other scenarios. Indeed, such SNe may be observationally dominated by systems experiencing huge mass loss in the final $10^3$ yr, leading to luminous SNe IIn or initially bright SNe IIP or IIL with characteristics of SNe IIn in their early spectra.
description: 18 pages, 12 figures, Accepted for publication in The Astrophysical Journal
Towards a theoretical description of dense QCD
Creators: name: Philipsen, Owe
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The properties of matter at finite baryon densities play an important role for the astrophysics of compact stars as well as for heavy ion collisions or the description of nuclear matter. Because of the sign problem of the quark determinant, lattice QCD cannot be simulated by standard Monte Carlo at finite baryon densities. I review alternative attempts to treat dense QCD with an effective lattice theory derived by analytic strong coupling and hopping expansions, which close to the continuum is valid for heavy quarks only, but shows all qualitative features of nuclear physics emerging from QCD. In particular, the nuclear liquid gas transition and an equation of state for baryons can be calculated directly from QCD. A second effective theory based on strong coupling methods permits studies of the phase diagram in the chiral limit on coarse lattices.
description: 10 pages, 9 figures; Contribution to the "12th Quark Confinement and the Hadron Spectrum" conference, Thessaloniki, 28.08.-04.09.2016
The Soyokaze: A Gentle Wind That Weathered the Storm
Creators: name: Boyce, Beth
Publisher: name: BC Studies: The British Columbian Quarterly
Year: 2020

description: The Canadian government confiscated 1,137 fishing vessels from Japanese Canadian fishing communities during the Second World War. These boats were then sold for below market prices, while the fishers and their families were uprooted, detained, dispossessed and exiled. Of the 1,137 vessels taken from their owners, only one was successfully reclaimed following the war. This is the story of the Soyokaze, a cod-fishing vessel built in 1939 for Shigekazu Matsunaga. It was seized and sold in 1942, but was later found, reclaimed and fished again by the Matsunaga family until it was donated to the Museum at Campbell River where it rests today, overlooking its old fishing grounds. Its longevity is a testament not only to the fine craftsmanship of Japanese Canadian boat builders, but also to the resilience of a family in the face of imposed life-altering government policies fueled by racism and fear.
description: BC Studies: The British Columbian Quarterly, No 204 (2020): (Un)Settling the Islands: Race, Indigeneity, and the Transpacific
Localization and symmetry breaking in the quantum quasiperiodic Ising glass
Creators: name: Chandran, Anushya
name: Laumann, C. R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Quasiperiodic modulation can prevent isolated quantum systems from equilibrating by localizing their degrees of freedom. In this article, we show that such systems can exhibit dynamically stable long-range orders forbidden in equilibrium. Specifically, we show that the interplay of symmetry breaking and localization in the quasiperiodic quantum Ising chain produces a \emph{quasiperiodic Ising glass} stable at all energy densities. The glass order parameter vanishes with an essential singularity at the melting transition with no signatures in the equilibrium properties. The zero temperature phase diagram is also surprisingly rich, consisting of paramagnetic, ferromagnetic and quasiperiodically alternating ground state phases with extended, localized and critically delocalized low energy excitations. The system exhibits an unusual quantum Ising transition whose properties are intermediate between those of the clean and infinite randomness Ising transitions. Many of these results follow from a geometric generalization of the Aubry-André duality which we develop. The quasiperiodic Ising glass may be realized in near term quantum optical experiments.
description: 19 pages, 6 figures, Comments welcome
Tripartite entangled plaquette state in a cluster magnet
Creators: name: Carrasquilla, Juan
name: Chen, Gang
name: Melko, Roger G.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Using large-scale quantum Monte Carlo simulations we show that a spin-$1/2$ XXZ model on a two-dimensional anisotropic Kagome lattice exhibits a tripartite entangled plaquette state that preserves all of the Hamiltonian symmetries. It is connected via phase boundaries to a ferromagnet and a valence-bond solid that break U(1) and lattice translation symmetries, respectively. We study the phase diagram of the model in detail, in particular the transitions to the tripartite entangled plaquette state, which are consistent with conventional order-disorder transitions. Our results can be interpreted as a description of the charge sector dynamics of a Hubbard model applied to the description of the spin liquid candidate ${\mathrm{LiZn}}_{2}{\mathrm{Mo}}_{3}{\mathrm{O}}_{8}$, as well as a model of strongly correlated bosonic atoms loaded onto highly tunable {\it trimerized} optical Kagome lattices.
description: 10 pages, 10 figures
ZrgA contributes to zinc acquisition in Vibrio parahaemolyticus
Creators: name: Zheng, Chengkun
name: Qiu, Jun
name: Zhai, Yimeng
name: Wei, Man
name: Zhou, Xiaohui
name: Jiao, Xinan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Metals are nutrients essential for almost all lifeforms. Bacteria have evolved several mechanisms to overcome the metal restrictions imposed by the host. Vibrio parahaemolyticus causes severe threats to public health and significant economic losses in shrimp aquaculture. Herein, we report that ZrgA contributes to zinc acquisition in this pathogen. The operon VP_RS01455 to VP_RS01475 of V. parahaemolyticus encodes the putative Zn transporter ZrgABCDE, whose homologs are widely distributed in Vibrionaceae. RNA sequencing analysis revealed that V. parahaemolyticus modulates the transcriptome in response to Zn limitation. Genes in the Zinc uptake regulator (Zur) regulon are upregulated during Zn limitation, including three genes annotated to encode Zn-binding proteins. Significant upregulation of these three genes during Zn limitation was also confirmed by quantitative real-time PCR (qRT-PCR) analysis. However, only the mutants containing a VP_RS01470 (zrgA) deletion exhibited impaired growth under Zn-deficient conditions, indicating that VP_RS01470 plays the predominant role in V. parahaemolyticus Zn acquisition. The VP_RS01470 deletion mutant displayed a false appearance of decreased swimming motility under Zn-deficient conditions, as revealed by the fact that the polar flagellar-related genes were not downregulated in the mutant. Moreover, VP_RS01470 deletion produced no noticeable impact on the swarming motility and virulence in mice. qRT-PCR analysis and β-galactosidase activity assays indicated that Zur negatively regulates VP_RS01470 expression in V. parahaemolyticus. Collectively, our findings suggest that ZrgA is required for Zn acquisition in V. parahaemolyticus and highlight the importance of detecting the expression of flagellar genes during analysis of motility of a mutant deficient in growth.
Additional file 2 of Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
Creators: name: Huang, Zegui
name: Ding, Xiong
name: Yue, Qing
name: Wang, Xianxuan
name: Chen, Zekai
name: Cai, Zefeng
name: Li, Weijian
name: Cai, Zhiwei
name: Chen, Guanzhi
name: Lan, Yulong
name: Wu, Weiqiang
name: Wu, Shouling
name: Chen, Youren
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Neuroscience
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Hematology

description: Additional file 2: Table S1. Sensitivity Analysis of additionally adjusted for TyG in 2006. Table S2. Sensitivity Analysis of additionally adjusted for TyG in 2010. Table S3. Sensitivity Analysis of adjusted for the change degree of covariates from 2006 to 2010. Table S4. Sensitivity Analysis of excluding Outcome Events within the first year of follow-up. Table S5. Sensitivity Analysis of excluding participants with the history of atrial fibrillation. Table S6. Sensitivity Analysis of excluding participants with the use of anti-hypertensive drugs, hypoglycemic drugs or lipid-lowering drugs, respectively.
Bildmittenübersicht/Index Map 1:500 000 Ekström-Schelfeis, Antarktis-Expedition 1983/84
Creators: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Publisher: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Year: 1984
Subjects: Antarctica
Flight index map
Ekström-Schelfeis
Ekströmisen
Atka-Bucht
Atka Iceport
Atkabukta
Station Georg von Neumayer (DE)
Kronprinsesse Märtha Kyst
Neuschwabenland
Dronning Maud Land

description: Flight index map of vertical aerial photography, 1983/84 expedition; Accuracy referred to geographic graticule only approximated; Photographic material, Aerial photo scale, Flight dates, see map legend; Scale: 1:500000;Projection: Lambert Conformal Conic;Bounding Box: POLYGON ((-11 -70, -5 -70, -5 -72, -11 -72, -11 -70))
Additional file 1: of Establishing core outcome sets for phenylketonuria (PKU) and medium-chain Acyl-CoA dehydrogenase (MCAD) deficiency in children: study protocol for systematic reviews and Delphi surveys
Creators: name: Potter, Beth
name: Hutton, Brian
name: Clifford, Tammy
name: Pallone, Nicole
name: Smith, Maureen
name: Stockler, Sylvia
name: Pranesh Chakraborty
name: Barbeau, Pauline
name: Garritty, Chantelle
name: Pugliese, Michael
name: Alvi Rahman
name: Skidmore, Becky
name: Tessier, Laure
name: Tingley, Kylie
name: Coyle, Doug
name: Greenberg, Cheryl
name: Korngut, Lawrence
name: MacKenzie, Alex
name: Mitchell, John
name: Nicholls, Stuart
name: Offringa, Martin
name: Schulze, Andreas
name: Taljaard, Monica
Publisher: name: figshare
Year: 2017
Subjects: Space Science
Medicine
Cell Biology
Developmental Biology
Computational Biology

description: Additional details on the methods for the rapid review and evidence map. (PDF 174 kb)
Recommendations for Redressing Historical Wrongs against Japanese Canadians in BC (excerpt)
Creators: name: Canadians Community Consultations Report, National Association Of Japanese
Publisher: name: BC Studies: The British Columbian Quarterly
Year: 2020

description: BC Studies: The British Columbian Quarterly, No 204 (2020): (Un)Settling the Islands: Race, Indigeneity, and the Transpacific
title: DEMEDARTS. (Dementia.Empathy.Education.Arts.)
title: Artistic Research.  Künstlerische Forschung zu Wahrnehmungs- und Handlungsmustern im Kontext einer alternden Gesellschaft.
titleType: Subtitle
Creators: name: Mateus-Berr, Ruth
Publisher: name: University of Applied Arts Vienna
publisherIdentifier: https://ror.org/05yjy4360
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Dementia
Artistic Research
Arts
Design
Education
Ageism, Empathy
alternde Gesellschaft, Wahrnehmungsmuster

description: Artistic Research on Patterns of Perception and Action in the Context of an Aging Society

DEMEDARTS is an arts-based research project, located at the University of Applied Arts Vienna (Center for Didactics of Art and Interdisciplinary Education) and funded by the Austrian Science Fund (FWF), within the PEEK-program (Programm zur Erweiterung und Erschließung der Künste): Grant-DOI: 10.55776/AR609 The project ran from February 2020 to January 2024. INITIAL SITUATION There are currently more than fifty-five million people living with dementia worldwide, and nearly ten million new cases are added each year. At the same time, not only is there a demographic increase in elderly people, ageism – a significant factor in society’s attitude to dementia – is also on the rise. Unfortunately, there are no medical treatments yet to cure or contain dementia. Artistic research, however, offers a means of creating a sense of well-being for those affected; it also provides education for caregivers and mindfulness for the society.
description: Künstlerische Forschung zu Wahrnehmungs- und Handlungsmustern im Kontext einer alternden Gesellschaft

DEMEDARTS ist ein künstlerisches Forschungsprojekt, angesiedelt an der Universität für angewandte Kunst Wien (Zentrum Didaktik für Kunst und interdisziplinären Unterricht) und gefördert vom Österreichischen Wissenschaftsfonds (FWF) im Rahmen des PEEK-Programms (Programm zur Erweiterung und Erschließung der Künste): Grant-DOI: 10.55776/AR609 Projektlaufzeit: Februar 2020 bis Jänner 2024 AUSGANGSLAGE Derzeit leben weltweit mehr als fünfundfünfzig Millionen Menschen mit Demenz, und jedes Jahr kommen fast zehn Millionen neue Fälle hinzu. Gleichzeitig nimmt nicht nur die Zahl der älteren Menschen zu, sondern hiermit die Altersdiskriminierung - ein wichtiger Faktor für die Einstellung der Gesellschaft zur Demenz. Leider gibt es noch keine medizinischen Behandlungsmöglichkeiten, um Demenz zu heilen oder einzudämmen. Die künstlerische Forschung bietet jedoch eine Möglichkeit, den Betroffenen ein Gefühl des Wohlbefindens zu vermitteln und auch die Betreuer*innen zu schulen und die Gesellschaft zu sensibilisieren.
A Historic Day for BC First Nations. Now the Work Starts: UNDRIP starts us on a journey, but without work, co-operation and shared vision we will be lost
Creators: name: Sayers, Judith
Publisher: name: BC Studies: The British Columbian Quarterly
Year: 2020

description: BC Studies: The British Columbian Quarterly, No 204 (2020): (Un)Settling the Islands: Race, Indigeneity, and the Transpacific
An Improved Diffuse Foreground Subtraction by ILC method: CMB Map and Angular Power Spectrum using Planck and WMAP Observations
Creators: name: Sudevan, Vipin
name: Aluri, Pavan K.
name: Yadav, Sarvesh Kumar
name: Saha, Rajib
name: Souradeep, Tarun
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report an improved technique for diffuse foreground minimization from Cosmic Microwave Background (CMB) maps using a new multi-phase iterative internal-linear-combination (ILC) approach in harmonic space. The new procedure consists of two phases. In phase 1, a diffuse foreground cleaned map is obtained by performing a usual ILC operation in the harmonic space in a single iteration over the desired portion of the sky. In phase 2, we obtain the final foreground cleaned map using an iterative ILC approach also in the harmonic space, however, now, during each iteration of foreground minimization, some of the regions of the sky that are not being cleaned in the current iteration, are replaced by the corresponding cleaned portions of the phase 1 cleaned map. The new ILC method nullifies a foreground leakage signal that is otherwise inevitably present in the old and usual harmonic space iterative ILC method. The new method is flexible to handle input frequency maps, irrespective of whether or not they initially have the same instrumental and pixel resolution, by bringing them to a common and maximum possible beam and pixel resolution at the beginning of the analysis. This dramatically reduces data redundancy and hence memory usage and computational cost. During the ILC weight calculation it avoids any need to deconvolve partial sky spherical harmonic coefficients by the beam and pixel window functions, which in strict mathematical sense, is not well-defined for azimuthally symmetric window functions. Using WMAP 9-year and Planck-2015 published frequency maps we obtain a pair of foreground cleaned CMB maps and CMB angular power spectrum. Our power spectrum match well with Planck-2015 results, with some difference. Finally, we show that the weights for ILC foreground minimization have an intrinsic characteristic that it tends to produce a statistically isotropic CMB map as well.
description: 17 pages, 17 figures
Additional file 1 of Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
Creators: name: Huang, Zegui
name: Ding, Xiong
name: Yue, Qing
name: Wang, Xianxuan
name: Chen, Zekai
name: Cai, Zefeng
name: Li, Weijian
name: Cai, Zhiwei
name: Chen, Guanzhi
name: Lan, Yulong
name: Wu, Weiqiang
name: Wu, Shouling
name: Chen, Youren
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Neuroscience
Biotechnology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Hematology

description: Additional file 1: Fig. S1. Flow chart of inclusion and exclusion. The flowchart of 19,924 hypertensive patients included in the final analyses.
Isotropic turbulence in compact space
Creators: name: Gravanis, Elias
name: Akylas, Evangelos
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences
subject: 76F05, 76F30

description: Isotropic turbulence is typically studied numerically through the direct numerical simulations (DNS). The DNS flows are described by the Navier-Stokes equation in a 'box', defined through periodic boundary conditions. The DNS flows live in a compact space and they are not isotropic in their large scales. The investigation of important phenomena of isotropic turbulence, such as anomalous scaling, through the DNS is affected by large scale effects. In this work we put isotropic turbulence - or better, the associated formal theory - in a 'box', through imposing periodicity at the level of the correlations functions. We offer a framework where one may investigate isotropic theories/models through the data of DNS in a formally consistent manner. We work at the level of the Karman-Howarth equation. Unlike the Navier-Stokes equation, infinitely smooth periodicity is obstructed in this theory, a fact expressed by a sequence of relations obeyed by the normal modes of the Karman-Howarth equation. Similar relations are imparted to the two-point functions under the condition that the energy spectrum and energy transfer function are realizable. Naturally constructed closures scheme for the Karman-Howarth equation do not conform to such relations, thereby destroying realizability. A closure can be made to conform to a finite number of them by adding corrective terms, in a procedure which possesses certain analogies with the renormalization of quantum field theory. The spectrum becomes unphysical (through sign-changing oscillations) for infinitely large wavenumbers, but we can controllably extend the regime where the spectrum remains physical deep enough in the dissipation range so that to be realistically adequate. We show that one or two such 'regularity relations' are needed at most for comparisons of the predictions of the theory with the current resolution level results of the DNS.
description: 57 pages, 3 figures
ZrgA contributes to zinc acquisition in Vibrio parahaemolyticus
Creators: name: Zheng, Chengkun
name: Qiu, Jun
name: Zhai, Yimeng
name: Wei, Man
name: Zhou, Xiaohui
name: Jiao, Xinan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Metals are nutrients essential for almost all lifeforms. Bacteria have evolved several mechanisms to overcome the metal restrictions imposed by the host. Vibrio parahaemolyticus causes severe threats to public health and significant economic losses in shrimp aquaculture. Herein, we report that ZrgA contributes to zinc acquisition in this pathogen. The operon VP_RS01455 to VP_RS01475 of V. parahaemolyticus encodes the putative Zn transporter ZrgABCDE, whose homologs are widely distributed in Vibrionaceae. RNA sequencing analysis revealed that V. parahaemolyticus modulates the transcriptome in response to Zn limitation. Genes in the Zinc uptake regulator (Zur) regulon are upregulated during Zn limitation, including three genes annotated to encode Zn-binding proteins. Significant upregulation of these three genes during Zn limitation was also confirmed by quantitative real-time PCR (qRT-PCR) analysis. However, only the mutants containing a VP_RS01470 (zrgA) deletion exhibited impaired growth under Zn-deficient conditions, indicating that VP_RS01470 plays the predominant role in V. parahaemolyticus Zn acquisition. The VP_RS01470 deletion mutant displayed a false appearance of decreased swimming motility under Zn-deficient conditions, as revealed by the fact that the polar flagellar-related genes were not downregulated in the mutant. Moreover, VP_RS01470 deletion produced no noticeable impact on the swarming motility and virulence in mice. qRT-PCR analysis and β-galactosidase activity assays indicated that Zur negatively regulates VP_RS01470 expression in V. parahaemolyticus. Collectively, our findings suggest that ZrgA is required for Zn acquisition in V. parahaemolyticus and highlight the importance of detecting the expression of flagellar genes during analysis of motility of a mutant deficient in growth.
Additional file 1: of Development and validation of a new tool to measure the facilitators, barriers and preferences to exercise in people with osteoporosis
Creators: name: Rodrigues, Isabel
name: Adachi, Jonathan
name: Beattie, Karen
name: MacDermid, Joy
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Appendix A. Critical appraisal of the checklist of facilitators and barriers to exercise. The content validity survey invited experts (healthcare professionals and researchers) to evaluate whether items in the PEQ were relevant, clear and essential. Additional file 1: Appendix A is a critical appraisal sheet with the following four inquiries: 1) the relevance of each question in the tool (how important the question is); 2) the clarity of each question (how clear the wording is); 3) the essentiality of each question (how necessary the question is); and 4) recommendations. (PDF 751 kb)
The pseudokinase MLKL contributes to host defense against Streptococcus pluranimalium infection by mediating NLRP3 inflammasome activation and extracellular trap formation
Creators: name: Lei, Yu-Xin
name: Liu, Yang
name: Xing, Li-Hua
name: Wu, Yu-Jing
name: Wang, Xue-Yin
name: Meng, Fan-Hua
name: Lou, Ya-Nan
name: Ma, Zhao-Guo
name: Yuan, Lin
name: Yu, Shui-Xing
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Host innate immunity plays a pivotal role in the early detection and neutralization of invading pathogens. Here, we show that pseudokinase mixed lineage kinase-like protein (MLKL) is required for host defence against Streptococcus pluranimalium infection by enhancing NLRP3 inflammasome activation and extracellular trap formation. Notably, Mlkl deficiency leads to increased mortality, increased bacterial colonization, severe destruction of organ architecture, and elevated inflammatory cell infiltration in murine models of S. pluranimalium pulmonary and systemic infection. In vivo and in vitro data provided evidence that potassium efflux-dependent NLRP3 inflammasome signalling downstream of active MLKL confers host protection against S. pluranimalium infection and initiates bacterial killing and clearance. Moreover, Mlkl deficiency results in defects in extracellular trap-mediated bactericidal activity. In summary, this study revealed that MLKL mediates the host defence response to S. pluranimalium, and suggests that MLKL is a potential drug target for preventing and controlling pathogen infection.
Design and implementation of an adaptive critic-based neuro-fuzzy controller on an unmanned bicycle
Creators: name: Shafiekhani, Ali
name: Mahjoob, Mohammad J.
name: Akraminia, Mehdi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Fuzzy critic-based learning forms a reinforcement learning method based on dynamic programming. In this paper, an adaptive critic-based neuro-fuzzy system is presented for an unmanned bicycle. The only information available for the critic agent is the system feedback which is interpreted as the last action performed by the controller in the previous state. The signal produced by the critic agent is used along with the error back propagation to tune (online) conclusion parts of the fuzzy inference rules of the adaptive controller. Simulations and experiments are conducted to evaluate the performance of the proposed controller. The results demonstrate superior performance of the developed controller in terms of improved transient response, robustness to model uncertainty and fast online learning.
description: 24 pages, 17 figures, Mechatronics Journal
Bildmittenübersicht/Index Map 1:500 000 Ritscher-Hochland (Borgmassiv/Ahlmannrücken), Antarktisexpedition 1983/84
Creators: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Publisher: name: Institut für Angewandte Geodäsie (Now: Bundesamt für Kartographie und Geodäsie), Frankfurt am Main
Year: 1984
Subjects: Antarctica
Flight index map
Ritscherhochland
Borgmassivet
Ahlmannryggen
Station Grunehogna (ZA)
Førstefjell
Boreas
Passat

description: Flight index map of vertical and oblique aerial photography, 1983/84 expedition; Accuracy referred to geographic graticule only approximated; Photographic material, Aerial photo scale and flight dates, see map legend; Scale: 1:500000;Projection: Lambert Conformal Conic;Bounding Box: POLYGON ((-6 -71, 0 -71, 0 -73, -6 -73, -6 -71))
Additional file 7: Figure S6. of Divergent regulation of Arabidopsis SAUR genes: a focus on the SAUR10-clade
Creators: name: Mourik, Hilda Van
name: Dijk, Aalt Van
name: Stortenbeker, Niek
name: Angenent, Gerco
name: Bemer, Marian
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: The location of GUS expression does not change after IAA-BR treatment. (PDF 373 kb)
Commemorating John A. Macdonald: Collective Remembering and the Structure of Settler Colonialism in British Columbia
Creators: name: Stanley, Timothy J
Publisher: name: BC Studies: The British Columbian Quarterly
Year: 2020

description: The 2018 controversy surrounding the decision of the mayor and council of the City of Victoria, BC, to remove a statue of John A. Macdonald from the entrance to city hall raises questions about how lived histories of colonialism and racisms are marked in landscape of collective remembering within the city and more broadly within Canada. Building of the work of James Wertsch on collective remembering, Eileen Moreton Robinson on private property and Patrick Wolfe on settler colonialism, this paper explores how the cultural markings of the City of Victoria have been produced by processes of colonization and racist exclusion. In particular, it discusses how such things as the dominance of English, the nature of place names, the marginalization Indigenous and Chinese people within the territory have come to be and how this making is erased from technologies of remembering. The paper contrasts the historical John A. Macdonald and his colonizing and racist practices his celebration by nationalists today. In so doing it show how the positions of the Macdonald apologists enact the same exclusions as those of the colonizing landscape. It conclude sby considering the implications of this structure of colonized remembering for transformative projects of decolonization and antiracism.
description: BC Studies: The British Columbian Quarterly, No 204 (2020): (Un)Settling the Islands: Race, Indigeneity, and the Transpacific
One-step preparation of a self-assembled bioconjugate nanovaccine against Brucella
Creators: name: Huang, Jing
name: Guo, Yan
name: Yu, Shujuan
name: Wang, Dongshu
name: Li, Shulei
name: Wu, Jun
name: Sun, Peng
name: Zhu, Li
name: Wang, Hengliang
name: Pan, Chao
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Brucellosis, caused by Brucella, is a severe zoonosis, and the current Brucella live attenuated vaccine cannot be used in humans due to major safety risks. Although polysaccharide antigens can be used to prepare the Brucella vaccine, their lower immunogenicity limits them from producing efficient and broad protection. In this study, we produced a high-performance bioconjugate nanovaccine against different species of Brucella by introducing a self-assembly nanoparticle platform and an O-linked glycosylation system into Yersinia enterocolitica serotype O:9, which has an O-polysaccharide composed of the same unit as Brucella. After successfully preparing the vaccine and confirming its stability, we subsequently demonstrated the safety of the vaccine in mice by high-dose immunization. Then, by a series of mouse experiments, we found that the nanovaccine greatly promoted antibody responses. In particular, the increase of IgG2a was more obvious than that of IgG1. Most importantly, this nanovaccine could provide cross-protection against B. abortus, B. melitensis, and B. suis strains by lethal dose challenged models, and could improve the clearance of B. melitensis, the most common pathogenic species in human brucellosis, by non-lethal dose infection. Overall, for the first time, we biocoupled polysaccharide antigens with nano carriers to prepare a Brucella vaccine, which showed pronounced and extensive protective effects in mice. Thus, we provided a potential candidate vaccine and a new direction for Brucella vaccine design.
The Murakami Women of Saltspring Island
Creators: name: Smallshaw, Brian
Publisher: name: BC Studies: The British Columbian Quarterly
Year: 2020

description: After Pearl Harbor during World War Two, the Murakami family of Saltspring Island was forcibly removed to the BC interior together with about 22,000 other Japanese Canadians. Almost uniquely, they chose to return to the place from where they had been uprooted and some members have lived on the island ever since. Back on Saltspring they were unable to buy their farms back, and in the face of hostility and racism were forced to begin anew, much as they had done half a century earlier on the island. This article focuses on the Murakami women, who have been a driving force on a number of levels: the operation of the family farms; surviving and surmounting incarceration during and after the war; and in the struggle to reestablish themselves on Saltspring and raise awareness of the history of Japanese Canadians on the island.
description: BC Studies: The British Columbian Quarterly, No 204 (2020): (Un)Settling the Islands: Race, Indigeneity, and the Transpacific
Supplementary material of this manscuript from GuUGT, a glycosyltransferase from Glycyrrhiza uralensis, exhibits glycyrrhetinic acid 3- and 30-O-glycosylation
Creators: name: Huang, Ying
name: Li, Da
name: Wang, Jinhe
name: Cai, Yi
name: Dai, Zhubo
name: Jiang, Dan
name: Liu, Chunsheng
Publisher: name: The Royal Society
Year: 2019

description: Supplementary tables of primers used in this study