cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Feature Learning from Incomplete EEG with Denoising Autoencoder
Creators: name: Li, Junhua
name: Struzik, Zbigniew
name: Zhang, Liqing
name: Cichocki, Andrzej
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: An alternative pathway for the human brain to communicate with the outside world is by means of a brain computer interface (BCI). A BCI can decode electroencephalogram (EEG) signals of brain activities, and then send a command or an intent to an external interactive device, such as a wheelchair. The effectiveness of the BCI depends on the performance in decoding the EEG. Usually, the EEG is contaminated by different kinds of artefacts (e.g., electromyogram (EMG), background activity), which leads to a low decoding performance. A number of filtering methods can be utilized to remove or weaken the effects of artefacts, but they generally fail when the EEG contains extreme artefacts. In such cases, the most common approach is to discard the whole data segment containing extreme artefacts. This causes the fatal drawback that the BCI cannot output decoding results during that time. In order to solve this problem, we employ the Lomb-Scargle periodogram to estimate the spectral power from incomplete EEG (after removing only parts contaminated by artefacts), and Denoising Autoencoder (DAE) for learning. The proposed method is evaluated with motor imagery EEG data. The results show that our method can successfully decode incomplete EEG to good effect.
description: The paper was accepted for publication by Neurocomputing
Testing a scaling relation between coherent radio emission and physical parameters of hot magnetic stars
Creators: name: Das, Barnali
name: Chandra, Poonam
name: Shultz, Matt E.
name: Leto, Paolo
name: Mikulášek, Zdeněk
name: Petit, Véronique
name: Wade, Gregg A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Coherent radio emission via electron cyclotron maser emission (ECME) from hot magnetic stars was discovered more than two decades ago, but the physical conditions that make the generation of ECME favourable remain uncertain. Only recently was an empirical relation, connecting ECME luminosity with the stellar magnetic field and temperature, proposed to explain what makes a hot magnetic star capable of producing ECME. This relation was, however, obtained with just fourteen stars. Therefore, it is important to examine whether this relation is robust. With the aim of testing the robustness, we conducted radio observations of five hot magnetic stars. This led to the discovery of three more stars producing ECME. We find that the proposed scaling relation remains valid after the addition of the newly discovered stars. However we discovered that the magnetic field and effective temperature correlate for $T_\mathrm{eff}\lesssim 16$ kK (likely an artifact of the small sample size), rendering the proposed connection between ECME luminosity and $T_\mathrm{eff}$ unreliable. By examining the empirical relation in light of the scaling law for incoherent radio emission, we arrive at the conclusion that both types of emission are powered by the same magnetospheric phenomenon. Like the incoherent emission, coherent radio emission is indifferent to $T_\mathrm{eff}$ for late-B and A-type stars, but $T_\mathrm{eff}$ appears to become important for early-B type stars, possibly due to higher absorption, or, higher plasma density at the emission sites suppressing the production of the emission.
description: 14 pages, 12 figures, accepted for publication in MNRAS
CD200 is induced by ERK and is a potential therapeutic target in melanoma
Creators: name: Bear, James E.
name: McKinnon, Karen
name: Petermann, Kimberly B.
name: Penland, Shannon
name: Thomas, Nancy E.
name: Buehler, Christin
name: Sharpless, Norman E.
name: Shields, Janiel M.
name: Zedek, Daniel
name: Serody, Jonathan S.
name: Rozenberg, Gabriela I.
name: Kim, William Y.
name: Groben, Pamela
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Immune-mediated antitumor responses occur in patients with metastatic melanoma (MM), and therapies designed to augment such responses are clinically beneficial. Despite the immunogenicity of melanoma, immunomodulatory therapies fail in the majority of patients with MM. An inability of DCs to sufficiently activate effector cells may, in part, underlie this failure of the antitumor response seen in most patients. In this work, we show that mutation of N-RAS or B-RAF, signature genetic lesions present in most MMs, potently induced the expression of cell-surface CD200, a repressor of DC function. Employing 2 independent, genome-wide microarray analyses, we identified CD200 as a highly dynamic, downstream target of RAS/RAF/MEK/ERK activation in melanoma. CD200 protein was similarly overexpressed in human melanoma cell lines and primary tumors. CD200 mRNA expression correlated with progression and was higher in melanoma than in other solid tumors or acute leukemia. Melanoma cell lines expressing endogenous CD200 repressed primary T cell activation by DCs, while knockdown of CD200 by shRNA abrogated this immunosuppressive effect. These data indicate that in addition to its effects on growth, survival, and motility, ERK activation in MM attenuates a host antitumor immune response, implicating CD200 and its interaction with the CD200 receptor as a potential therapeutic target for MM.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 6 (53)]
Creators: name: De Cremona, Michael
name: De Cremona, Johannes
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1421
Subjects: subject: Sonstige weltliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Die Brüder Michael und Johannes de Cremona, Söhne und Erben des verstorbenen Antonius sowie der verstorbenen Comina de Serina, aus der Nachbarschaft St. Lucae in Cremona verkaufen dem Antonius de Scandolariis, Sohn des verstorbenen Basarinus, wohnhaft ebendort, mit Erlaubnis des Franciscus de Biresis, praepositus des Klosters St. Cataldi in Cremona, ein bebautes Stück Land, gelegen in der genannten Nachbarschaft St. Lucae.
Existence and Non-Existence of Doubly Heavy Tetraquark Bound States
Creators: name: Pflaumer, Martin
name: Leskovec, Luka
name: Meinel, Stefan
name: Wagner, Marc
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: In this work we investigate the existence of bound states for doubly heavy tetraquark systems $ \bar{Q}\bar{Q}'qq' $ in a full lattice-QCD computation, where heavy bottom quarks are treated in the framework of non-relativistic QCD. We focus on three systems with quark content $ \bar{b}\bar{b}ud $, $ \bar{b}\bar{b}us $ and $ \bar{b}\bar{c}ud $. We show evidence for the existence of $ \bar{b}\bar{b}ud $ and $ \bar{b}\bar{b}us $ bound states, while no binding appears to be present for $ \bar{b}\bar{c}ud $. For the bound four-quark states we also discuss the importance of various creation operators and give an estimate of the meson-meson and diquark-antidiquark percentages.
description: 9 pages, 9 figures, talk given at the 38th International Symposium on Lattice Field Theory (LATTICE2021), 26th-30th July 2021, Zoom/Gather@Massachusetts Institute of Technology
A family of potential-density pairs for galactic bars
Creators: name: Dehnen, Walter
name: Aly, Hossam
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present a family of analytical potential-density pairs for barred discs, which can be combined to describe galactic bars in a realistic way, including boxy/peanut components. We illustrate this with two reasonable compound models. Computer code for the evaluation of potential, forces, density, and projected density is freely provided.
description: 10 pages, accepted for publication at MNRAS
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR
Creators: name: Kreda, Silvia M.
name: Chen, Yun
name: Gentzsch, Martina
name: Scarlett, Cameron O.
name: Jacobson, Ken
name: Milgram, Sharon L.
name: Borchers, Christoph H.
name: Thelin, William R.
name: Sallee, Jennifer L.
name: Stutts, M. Jackson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The role of the cystic fibrosis transmembrane conductance regulator (CFTR) as a cAMP-dependent chloride channel on the apical membrane of epithelia is well established. However, the processes by which CFTR is regulated on the cell surface are not clear. Here we report the identification of a protein-protein interaction between CFTR and the cytoskeletal filamin proteins. Using proteomic approaches, we identified filamins as proteins that associate with the extreme CFTR N terminus. Furthermore, we identified a disease-causing missense mutation in CFTR, serine 13 to phenylalanine (S13F), which disrupted this interaction. In cells, filamins tethered plasma membrane CFTR to the underlying actin network. This interaction stabilized CFTR at the cell surface and regulated the plasma membrane dynamics and confinement of the channel. In the absence of filamin binding, CFTR was internalized from the cell surface, where it prematurely accumulated in lysosomes and was ultimately degraded. Our data demonstrate what we believe to be a previously unrecognized role for the CFTR N terminus in the regulation of the plasma membrane stability and metabolic stability of CFTR. In addition, we elucidate the molecular defect associated with the S13F mutation.
Light quark decays of doubly heavy baryons in light front approach
Creators: name: Liu, Hang
name: Xing, Zhi-Peng
name: Yang, Chang
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We explore the semileptonic and nonleptonic decays of doubly heavy baryons $(Ω_{cc}^ {(*) +}, Ω_{bb}^ {(*)0}, Ω_{bc}^ {(*) -}, Ω_{bc}^ {\prime 0}) $ induced by the $s\to u$ transition. Hadronic form factors are parametrized by transition matrix elements and are calculated in the light front quark model. With the form factors, we make use of helicity amplitudes and analyze semileptonic and nonleptonic decay modes of doubly heavy baryons. Benchmark results for partial decay widths, branching fractions, forward-backward asymmetries and other phenomenological observables are derived. We find that typical branching fractions for semileptonic decays into $\ell\barν$ are at the order $10^ {-7}-10^ {-8} $ and the ones for nonleptonic decays are at the order $10^ {-5} $, which are likely detectable such as in LHCb experiment. With the potential data accumulated in future, our results may help to shape our understanding of the decay mechanism in the presence of two heavy quarks.
description: 18 pages,8 figures
A theoretical model of an off-axis GRB jet
Creators: name: Kamenetskaia, B. Betancourt
name: Fraija, N.
name: Dainotti, M.
name: Gálvan-Gámez, A.
name: Duran, R. Barniol
name: Dichiara, S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In light of the most recent observations of late afterglows produced by the merger of compact objects or by the core-collapse of massive dying stars, we research the evolution of the afterglow produced by an off-axis top-hat jet and its interaction with a surrounding medium. The medium is parametrized by a power law distribution of the form $n(r)\propto r^{-k}$ is the stratification parameter and contains the development when the surrounding density is constant ($k=0$) or wind-like ($k=2$). We develop an analytical synchrotron forward-shock model when the outflow is viewed off-axis, and it is decelerated by a stratified medium. Using the X-ray data points collected by a large campaign of orbiting satellites and ground telescopes, we have managed to apply our model and fit the X-ray spectrum of the GRB afterglow associated to SN 2020bvc with conventional parameters. Our model predicts that its circumburst medium is parametrized by a power law with stratification parameter $k=1.5$.
description: Presented at the 37th International Cosmic Ray Conference (ICRC2021), Berlin, Germany
Angular Momentum Loss Rates in Be Stars Determined by the Viscous Decretion Disc Model
Creators: name: Ghoreyshi, M. R.
name: Jones, C. E.
name: Granada, A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Circumstellar discs around Be stars are formed by the material ejected by the central star. This process removes excess angular momentum from the star as viscosity facilitates the mass and angular momentum transfer within the disc and its growth. The angular momentum loss rates (AMLR) of Be stars is a subject of debate in the literature. Through the modelling of the disc formation and dissipation phases observed from Be stars, their average AMLR can be determined and this is the goal of this work. We use the viscous decretion disc (VDD) model to provide a range of the average AMLR for Be stars and compare these rates with predicted values from the literature. We explore the reasons for discrepancies between the predicted values of average AMLR using the VDD and Geneva stellar evolution (GSE) models that were previously reported in literature and find that the largest differences occur when Be stars are rotating below their critical speeds. We show that the time over which the mass reservoir builds up is inversely proportional to the average AMLR. Also, we determine a revised value of the average AMLR for the Galactic Be star omega CMa of 4.7x10^36 g cm^2/s^2, which is in better agreement with the values expected for a typical B2 type star. Finally, the effect of disc truncation due to the presence of a companion star is investigated and we find that this has a minimal effect on the average AMLR.
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia
Creators: name: Li, Wei-Ping
name: Jones, Christopher
name: Michaely, Peter
name: Cohen, Jonathan C.
name: Hobbs, Helen H.
name: Maeda, Nobuyo
name: Garuti, Rita
name: Herz, Joachim
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Genetic defects in LDL clearance result in severe hypercholesterolemia and premature atherosclerosis. Mutations in the LDL receptor (LDLR) cause familial hypercholesterolemia (FH), the most severe form of genetic hypercholesterolemia. A phenocopy of FH, autosomal recessive hypercholesterolemia (ARH), is due to mutations in an adaptor protein involved in LDLR internalization. Despite comparable reductions in LDL clearance rates, plasma LDL levels are substantially lower in ARH than in FH. To determine the metabolic basis for this difference, we examined the synthesis and catabolism of VLDL in murine models of FH (Ldlr–/–) and ARH (Arh–/–). The hyperlipidemic response to a high-sucrose diet was greatly attenuated in Arh–/– mice compared with Ldlr–/– mice despite similar rates of VLDL secretion. The rate of VLDL clearance was significantly higher in Arh–/– mice than in Ldlr–/– mice, suggesting that LDLR-dependent uptake of VLDL is maintained in the absence of ARH. Consistent with these findings, hepatocytes from Arh–/– mice (but not Ldlr–/– mice) internalized β-migrating VLDL (β-VLDL). These results demonstrate that ARH is not required for LDLR-dependent uptake of VLDL by the liver. The preservation of VLDL remnant clearance attenuates the phenotype of ARH and likely contributes to greater responsiveness to statins in ARH compared with FH.
Decelerated sub-relativistic material with energy Injection
Creators: name: Kamenetskaia, B. Betancourt
name: Fraija, N.
name: Dainotti, M.
name: Gálvan-Gámez, A.
name: Duran, R. Barniol
name: Dichiara, S.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We investigate the evolution of the afterglow produced by the deceleration of the non-relativistic material due to its surroundings. The ejecta mass is launched into the circumstellar medium with equivalent kinetic energy expressed as a power-law velocity distribution $E\propto (Γβ)^{-α}$. The density profile of this medium follows a power law $n(r)\propto r^{-k}$ with $k$ the stratification parameter, which accounts for the usual cases of a constant medium ($k=0$) and a wind-like medium ($k=2$). A long-lasting central engine, which injects energy into the ejected material as ($E\propto t^{1-q}$) was also assumed. With our model, we show the predicted light curves associated with this emission for different sets of initial conditions and notice the effect of the variation of these parameters on the frequencies, timescales and intensities. The results are discussed in the Kilonova scenario.
description: Presented at the 37th International Cosmic Ray Conference (ICRC2021), Berlin, Germany
Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis
Creators: name: Jacobs, William R.
name: Lee, Sunhee
name: Basaraba, Randall J.
name: Chen, Bing
name: Venkataswamy, Manjunatha M.
name: Porcelli, Steven A.
name: Braunstein, Miriam
name: Orme, Ian M.
name: Derrick, Steven C.
name: Morris, Sheldon L.
name: Jeon, Bo Y.
name: Chan, John
name: Hinchey, Joseph
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The inhibition of apoptosis of infected host cells is a well-known but poorly understood function of pathogenic mycobacteria. We show that inactivation of the secA2 gene in Mycobacterium tuberculosis, which encodes a component of a virulence-associated protein secretion system, enhanced the apoptosis of infected macrophages by diminishing secretion of mycobacterial superoxide dismutase. Deletion of secA2 markedly increased priming of antigen-specific CD8+ T cells in vivo, and vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Guérin vaccination. Our results define a mechanism for a key immune evasion strategy of M. tuberculosis and provide what we believe to be a novel approach for improving mycobacterial vaccines.
Shock-wave heating mechanism of the distant solar wind: explanation of Voyager-2 data
Creators: name: Korolkov, S. D.
name: Izmodenov, V. V.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: One of the important discoveries made by Voyager-2 is the nonadiabatic radial profile of the solar wind proton temperature. This phenomenon has been studied for several decades. The dissipation of turbulence energy has been proposed as the main physical process responsible for the temperature profile. The turbulence is both convected with the solar wind and originated in the solar wind by the compressions and shears in the flows and by pick-up ions. The compression source of the solar wind heating in the outer heliosphere appears due to shock waves, which originated either in the solar corona or in the solar wind itself. The goal of this work is to demonstrate that the shock-wave heating itself is enough to explain the temperature profile obtained by Voyager-2. The effect of shock-wave heating is demonstrated in the frame of a very simple spherically symmetric high-resolution (in both space and time) gas-dynamical data-driven solar wind model. This data-driven model employs the solar-wind parameters at 1 AU with minute resolution. The data are taken from the NASA OMNIWeb database. It is important to underline that (1) the model captures the shocks traveling and/or originating in the solar wind, and (2) other sources of heating are not taken into account in the model. We extended this simple model to the magnetohydrodynamic (MHD) and two-component models and found very similar results. The results of the numerical modeling with the one-minute OMNI data as the boundary condition show very good agreement with the solar-wind temperature profiles obtained by Voyager-2. It is also noteworthy that the numerical results with daily averaged OMNI data show a very similar temperature profile, while the numerical runs with 27-day-averaged OMNI data demonstrate the adiabatic behavior of the temperature.
description: 12 pages, 7 figures
Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC.. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis. J Clin Invest 117: 3879-3889
Creators: name: Rathmell, W. Kimryn
name: Simon, M. Celeste
name: Bezman, Natalie A.
name: Lam, Jennifer C.
name: Hickey, Michele M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The R200W mutation in the von Hippel-Lindau (VHL) tumor suppressor protein (pVHL) is unique in that it is not associated with tumor development, but rather with Chuvash polycythemia, a heritable disease characterized by elevated hematocrit and increased serum levels of erythropoietin and VEGF. Previous studies have implicated hypoxia-inducible factor-1alpha (HIF-1alpha) signaling in this disorder, although the effects of this mutation on pVHL function are not fully understood. In order to explore the mechanisms underlying the development of this polycythemia, we generated mice homozygous for the R200W mutation (Vhl(R/R)). Vhl(R/R) mice developed polycythemia highly similar to the human disease. The activity of HIF proteins, specifically the HIF-2alpha isoform, was upregulated in ES cells and tissues from Vhl(R/R) mice. Furthermore, we observed a striking phenotype in Vhl(R/R) spleens, with greater numbers of erythroid progenitors and megakaryocytes and increased erythroid differentiation of Vhl(R/R) splenic cells in vitro. These findings suggest that enhanced expression of key HIF-2alpha genes promotes splenic erythropoiesis, resulting in the development of polycythemia in Vhl(R/R) mice. This mouse model is a faithful recapitulation of this VHL-associated syndrome and represents a useful tool for studying polycythemias and investigating potential therapeutics.
The Phase Diagram of BPS Black Holes in AdS$_5$
Creators: name: Ezroura, Nizar
name: Larsen, Finn
name: Liu, Zhihan
name: Zeng, Yangwenxiao
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Motivated by recent studies of supersymmetric black holes, we revisit the phase diagram of AdS black holes, whether BPS or not, with particular emphasis on the role of rotation. We develop BPS thermodynamics systematically and, in many explicit examples, we study its striking similarities with more familiar AdS black holes, as well as some differences. We highlight an important fugacity that preserves BPS saturation but is not captured by the supersymmetric index.
description: 49 pages, references added, typos corrected, further discussion added
Parameterized Post-Einsteinian Framework for Precessing Binaries
Creators: name: Loutrel, Nicholas
name: Pani, Paolo
name: Yunes, Nicolás
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In general relativity, isolated black holes obey the no hair theorems, which fix the multipolar structure of their exterior spacetime. However, in modified gravity, or when the compact objects are not black holes, the exterior spacetime may have a different multipolar structure. When two black holes are in a binary, this multipolar structure determines the morphology of the dynamics of orbital and spin precession. In turn, the precession dynamics imprint onto the gravitational waves emitted by an inspiraling compact binary through specific amplitude and phase modulations. The detection and characterization of these amplitude and phase modulations can therefore lead to improved constraints on fundamental physics with gravitational waves. Recently, analytic precessing waveforms were calculated in two scenarios: (i) dynamical Chern-Simons gravity, where the no-hair theorems are violated, and (ii) deformed compact objects with generic mass quadrupole moments. In this work, we use these two examples to propose an extension of the parameterized post-Einsteinian~(ppE) framework to include precession effects. The new framework contains $2n$ ppE parameters $(\mathscr{b}^{\rm ppE}_{(m',n)}, b^{\rm ppE}_{(m',n)})$ for the waveform phase, and $2n$ ppE parameters $(\mathscr{a}^{\rm ppE}_{(m',n)}, a^{\rm ppE}_{(m',n)})$ for the waveform amplitudes. The number of ppE corrections $n$ corresponds to the minimum number of harmonics necessary to achieve a given likelihood threshold when comparing the truncated ppE waveform with the exact one, and $(m',n)$ corresponds to the harmonic numbers of the harmonics containing ppE parameters. We show explicitly how these ppE parameters map to the specific example waveforms discussed above. The proposed ppE framework can serve as a basis for future tests of general relativity with gravitational waves from precessing binaries.
description: 24 pages, 5 figures, published version
SEX DIFFERENCES IN HYPERTENSION MANAGEMENT USING KAPLAN-MEIER & LOG-RANK TEST
Creators: name: Ismail,, Abduljalil Alfa
name: Ibrahim,, Anas
Publisher: name: SADI Journal
Year: 2024
Subjects: hypertensive Management, Kaplan–Meier Estimator, Log-Rank Test, Gender Differences, Survival Analysis

description: This study investigated gender differences in hypertensive management by employing Kaplan–Meier Estimator and Log-Rank Test methodologies. Data were collected from 300 hypertensive patients at Specialist Hospital Sokoto between 2015 and 2021. The Kaplan–Meier survival curves demonstrated that the median times to achieve optimal hypertension control were 43.43 months (3.62 years) for men and 37.76 months (3.15 years) for women. Despite these differences, the log-rank test revealed no significant differences in survival curves between genders (p = 0.259). These findings suggest that sex did not significantly influence the time to optimal hypertensive management in this cohort. The findings of this study underscore the need for further research with larger sample sizes to explore potential variations in hypertensive management across different demographics. The recommendations include personalized patient care strategies and continued public health efforts to ensure equitable hypertensive management
Crystalline Field Effects on Magnetic and Thermodynamic properties of a Ferrimagnetic Centered Rectangular Structure
Creators: name: Gharaibeh, Maen
name: Haifa, Rama Abu
name: Obeidat, Abdalla
name: Badarneh, Mohammad H. A.
name: Qaseer, M. K
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The magnetic properties and phase diagrams of the mixed spin Ising model, with spins S=1 and σ=1/2 on a centered rectangular structure, have been investigated using Monte Carlo simulations based on the Metropolis algorithm. Every spin at one lattice site has four nearest-neighbor spins of the same type and four of the other type. We have assumed ferromagnetic interaction between the same spins type, antiferromagnetic for different spin types. An additional single-site crystal field term on the S=1 site was considered. We have shown that the crystal field enhances the existence of the compensation behavior of the system. In addition, the effects of the crystal field and exchange coupling on the magnetic properties and phase diagrams of the system have been studied. Finally, the magnetic hysteresis cycles of the system for several values of the crystal field have been found.
description: 19 pages, 12 figures. arXiv admin note: text overlap with arXiv:2012.10920
Influence of Octahedral Site Chemistry on the Elastic Properties of Biotite
Creators: name: Hanlon, Dillon F.
name: Andrews, G. Todd
name: Mason, Roger A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Brillouin light scattering spectroscopy was used along with detailed composition information obtained from electron probe microanalysis to study the influence of octahedral site chemistry on the elastic properties of biotite crystals. Elastic wave velocities for a range of directions in the AC and BC crystallographic planes were obtained for each crystal by application of the Brillouin equation with refractive indices and phonon frequencies obtained from the Becke line test and spectral peak positions, respectively. In general, velocities increase with decreasing Fe content, approach those of muscovite at low Fe concentrations. 12 of the 13 elastic constants for the full monoclinic symmetry were obtained for each crystal by fitting analytic expressions for the velocities as functions of propagation direction and elastic constants to corresponding experimental data, with the remaining constant estimated using hexagonal symmetry. Elastic constants C11, C22, and C66 are comparable to those of muscovite and show little change with Fe concentration due to strong bonding within layers. In contrast, nearly all remaining constants show a pronounced dependence on Fe content, likely due to the weak interlayer bonding. Similar behaviour is shown by elastic stability, which falls greatly as Fe concentration increases, and elastic anisotropy within the basal cleavage plane, which decreases with Fe content. This consistent dependency of all measured elastic constants on Fe content suggests that biotite elasticity is a function of octahedral site chemistry and gives a method to determine the elastic constants and elastic stability of most biotite compositions provided, Fe or Mg concentrations are known. Moreover, the good agreement between elastic constants of Fe-poor biotite and those of phlogopite obtained from DFT simulations indicate a method to predict elastic properties of biotites.
description: 26 pages, 9 figures
From Spitzer Galaxy Photometry to Tully-Fisher Distances
Creators: name: Sorce, J. G.
name: Tully, R. B.
name: Courtois, H. M.
name: Jarrett, T. H.
name: Neill, J. D.
name: Shaya, E. J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: This paper involves a data release of the observational campaign: Cosmicflows with Spitzer (CFS). Surface photometry of the 1270 galaxies constituting the survey is presented. An additional ~ 400 galaxies from various other Spitzer surveys are also analyzed. CFS complements the Spitzer Survey of Stellar Structure in Galaxies, that provides photometry for an additional 2352 galaxies, by extending observations to low galactic latitudes (|b|<30 degrees). Among these galaxies are calibrators, selected in K band, of the Tully-Fisher relation. The addition of new calibrators demonstrate the robustness of the previously released calibration. Our estimate of the Hubble constant using supernova host galaxies is unchanged, H0 = 75.2 +/- 3.3 km/s/Mpc. Distance-derived radial peculiar velocities, for the 1935 galaxies with all the available parameters, will be incorporated into a new data release of the Cosmicflows project. The size of the previous catalog will be increased by 20%, including spatial regions close to the Zone of Avoidance.
description: Accepted for publication in MNRAS, 16 pages, 14 figures, 6 tables
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 6 (55)]
Creators: name: Jacobus
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1422
Subjects: subject: Sonstige weltliche Aussteller
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Jacobus de Comiribus aus Mede, Lizenziat für Zivilrecht und commissarius camerae appellatus, verurteilt in einem Streitfall zwischen Marchinus de Boxio, Sohn des verstorbenen Antonius, und Simon de Caualio, Sohn des verstorbenen Johanninus, Letzteren zur Zahlung eines Geldbetrages binnen acht Tagen.
$B_s$ mesons: semileptonic and nonleptonic decays
Creators: name: Albertus, C.
name: Hernandez, E.
name: Nieves, J.
name: Hidalgo-Duque, C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In this contribution we compute some nonleptonic and semileptonic decay widths of $B_s$ mesons, working in the context of constituent quark models \cite{Albertus:2014gba, Albertus:2014bfa}. For the case of semileptonic decays we consider reactions leading to kaons or different $J^π$ $D_s$ mesons. The study of nonleptonic decays has been done in the factorisation approximation and includes the final states enclosed in Table 2.
description: Contribution to the proceedings of the MESON 2014 Conference. 2 tables, 2 figures
Asteroseismology of PG 1541$+$651 and BPM 31594 with TESS
Creators: name: Romero, Alejandra D.
name: da Rosa, Gabriela Oliveira
name: Kepler, S. O.
name: Bradley, Paul A.
name: Uzundag, Murat
name: Bell, Keaton J.
name: Hermes, J. J.
name: Lauffer, G. R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present the photometric data from TESS for two known ZZ Ceti stars, PG 1541+651 and BPM 31594. Before TESS, both objects only had observations from short runs from ground-based facilities, with three and one period detected, respectively. The TESS data allowed the detection of multiple periodicities, 12 for PG 1541$+$651, and six for BPM 31594, which enables us to perform a detailed asteroseismological study. For both objects we found a representative asteroseismic model with canonical stellar mass ~ 0.61 Msun and thick hydrogen envelopes, thicker than 10^(-5.3) M_*. The detection of triplets in the Fourier transform also allowed us to estimate mean rotation periods, being ~22 h for PG 1541+651 and 11.6 h for BPM 31594, which is consistent with range of values reported for other ZZ Ceti stars.
description: 12 pages, 11 figures. Accepted for publication in MNRAS
Thermodynamic of Distorted Reissner-Nordström Black Holes in Five-dimensions
Creators: name: Abdolrahimi, Shohreh
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, we study mechanics and thermodynamics of distorted, five-dimensional, electrically charged (non-extremal) black holes on the example of a static and "axisymmetric" black hole distorted by external, electrically neutral matter. Such a black hole is represented by the derived here solution of the Einstein-Maxwell equations which admits an $\mathbb{R}^1\times U(1)\times U(1)$ isometry group. We study the properties of this distorted black hole.
description: 7 pages, submitted for the proceedings of the First Karl Schwarzschild Meeting (Frankfurt, 2013)
Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
Creators: name: Beg, Amer A.
name: Karin, Michael
name: Sahenk, Zarife
name: Carathers, Micheal
name: Weinstein, Michael
name: Bupha-Intr, Tepmanas
name: Villalta, S. Armando
name: Li, Zhi-Wei
name: Gardner, Katherine L.
name: Bakkar, Nadine
name: Janssen, Paul M.L.
name: Baldwin, Albert S.
name: Guttridge, Denis C.
name: Acharyya, Swarnali
name: Rafael-Fortney, Jill A.
name: Tidball, James G.
name: Ghosh, Sankar
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Duchenne muscular dystrophy (DMD) is a lethal X-linked disorder associated with dystrophin deficiency that results in chronic inflammation and severe skeletal muscle degeneration. In DMD mouse models and patients, we find that IκB kinase/NF-κB (IKK/NF-κB) signaling is persistently elevated in immune cells and regenerative muscle fibers. Ablation of 1 allele of the p65 subunit of NF-κB was sufficient to improve pathology in mdx mice, a model of DMD. In addition, conditional deletion of IKKβ in mdx mice elucidated that NF-κB functions in activated macrophages to promote inflammation and muscle necrosis and in skeletal muscle fibers to limit regeneration through the inhibition of muscle progenitor cells. Furthermore, specific pharmacological inhibition of IKK resulted in improved pathology and muscle function in mdx mice. Collectively, these results underscore the critical role of NF-κB in the progression of muscular dystrophy and suggest the IKK/NF-κB signaling pathway as a potential therapeutic target for DMD.
Pionic depth of the hadron gas after a heavy-ion collision
Creators: name: Fonfría, Guillermo Gómez
name: Llanes-Estrada, Felipe J.
name: Sucunza, Javier Suárez
name: Torres-Rincon, Juan M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The final stage of a relativistic heavy-ion collision is a hadron gas. Final-state interactions therein distort the $p_T$ spectrum of particles coming from the phase transition upon cooling the quark-gluon plasma. Using recent state-of-the-art parametrizations of pion interactions we provide theoretical computations of the pionic depth of the gas: how likely is it that a given pion rescatters in it (we find a high probability around $p_T=0.5$ GeV at midrapidity, corresponding to the formation of the $ρ$ resonance), a comparison of the collision and Bjorken expansion rates, and how many pions make it through without interacting as a function of $p_T$. This is in the range 10-24$\%$ and shown in this plot, the main result of the contribution.
description: 4 pages, 4 figures. Contribution to the proceedings of the European Physical Society Conference on High Energy Physics (EPS-HEP2021), 26-30 July 2021
Density-dependent thermopower oscillations in mesoscopic two-dimensional electron gases
Creators: name: Narayan, Vijay
name: Kogan, Eugene
name: Ford, Chris
name: Pepper, Michael
name: Kaveh, Moshe
name: Griffiths, Jonathan
name: Jones, Geb
name: Beere, Harvey
name: Ritchie, Dave
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present thermopower $S$ and resistance $R$ measurements on GaAs-based mesoscopic two-dimensional electron gases (2DEGs) as functions of the electron density $n_s$. At high $n_s$ we observe good agreement between the measured $S$ and $S_{\rm{MOTT}}$, the Mott prediction for a non-interacting metal. As $n_s$ is lowered, we observe a crossover from Mott-like behaviour to that where $S$ shows strong oscillations and even sign changes. Remarkably, there are absolutely no features in $R$ corresponding to those in $S$. In fact, $R$ is devoid of even any universal conductance fluctuations. A statistical analysis of the thermopower oscillations from two devices of dissimilar dimensions suggest a universal nature of the oscillations. We critically examine whether they can be mesoscopic fluctuations of the kind described by Lesovik and Khmelnitskii in Sov. Phys. JETP. \textbf{67}, 957 (1988).
description: New Journal of Physics (accepted)
New Local Volume Dwarf Galaxy Candidates from the DESI Legacy Imaging Surveys
Creators: name: Karachentsev, I. D.
name: Kaisina, E. I.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We undertook a search for new dwarf galaxies in the vicinity of relatively isolated nearby galaxies with distances $D < 12$ Mpc and stellar masses in the $2\times10^{11}-3\times10^8~M_{\odot}$ interval, using the data from the DESI Legacy Imaging Surveys. Around the 46 considered Local Volume galaxies, $67$ new candidates for satellites of these galaxies were found. About half of them are classified as spheroidal dwarfs of low surface brightness. The new galaxies are included in the Local Volume database (LVGDB), which now contains 1421 objects, being 63% more than the Updated Nearby Galaxy Catalog.
description: 21 pages, 4 figures, 2 tables, 1 Appendix (Images of candidate satellites for nearby massive galaxies, taken from DESI Legacy Imaging Surveys), accepted in Astrophysical Bulletin
Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease
Creators: name: Nankoe, Sharif R.
name: del Re, Elizabetta C.
name: Altintas, Mehmet M.
name: Wei, Changli
name: Hsing, Lianne
name: Kretzler, Matthias
name: Sever, Sanja
name: Reiser, Jochen
name: Henderson, Joel
name: Möller, Clemens C.
name: Nikolic, Boris
name: Ko, David
name: Rudensky, Alexander
name: Kerjaschki, Dontscho
name: Erickson, Ann
name: Cohen, Clemens D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Kidney podocytes and their foot processes maintain the ultrafiltration barrier and prevent urinary protein loss (proteinuria). Here we show that the GTPase dynamin is essential for podocyte function. During proteinuric kidney disease, induction of cytoplasmic cathepsin L leads to cleavage of dynamin at an evolutionary conserved site, resulting in reorganization of the podocyte actin cytoskeleton and proteinuria. Dynamin mutants that lack the cathepsin L site, or render the cathepsin L site inaccessible through dynamin self-assembly, are resistant to cathepsin L cleavage. When delivered into mice, these mutants restored podocyte function and resolve proteinuria. Our study identifies dynamin as a critical regulator of renal permselectivity that is specifically targeted by proteolysis under pathological conditions.
Physics of PT-Symmetric Quantum Systems at Finite Temperature
Creators: name: Du, Qian
name: Cao, Kui
name: Kou, Su-Peng
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study parity-time-symmetric non-Hermitian quantum systems at finite temperature, where the Boltzmann distribution law fails to hold. To characterize their abnormal physical properties, a new quantum statistics theory (the so-called quantum Liouvillian statistics theory) was developed, in which the Boltzmann distribution law was replaced by the Liouvillian-Boltzmann distribution law. Using it, we derived analytical results of thermodynamic properties for thermal PT systems and found that a "continuous" thermodynamic phase transition occurs at the exceptional point, where a zero-temperature anomaly exists.
Extending Optical Flare Models to the UV: Results from Comparing of TESS and GALEX Flare Observations For M Dwarfs
Creators: name: Jackman, James A. G.
name: Shkolnik, Evgenya
name: Million, Chase
name: Fleming, Scott
name: Richey-Yowell, Tyler
name: Loyd, Parke
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The ultraviolet (UV) emission of stellar flares may have a pivotal role in the habitability of rocky exoplanets around low-mass stars. Previous studies have used white-light observations to calibrate empirical models which describe the optical and UV flare emission. However, the accuracy of the UV predictions of models have previously not been tested. We combined TESS optical and GALEX UV observations to test the UV predictions of empirical flare models calibrated using optical flare rates of M stars. We find that the canonical 9000 K blackbody model used by flare studies underestimates the GALEX NUV energies of field age M stars by up to a factor of 6.5$\pm$0.7 and the GALEX FUV energies of fully convective field age M stars by 30.6$\pm$10.0. We calculated energy correction factors that can be used to bring the UV predictions of flare models closer in line with observations. We calculated pseudo-continuum flare temperatures that describe both the white-light and GALEX NUV emission. We measured a temperature of 10,700 K for flares from fully convective M stars after accounting for the contribution from UV line emission. We also applied our correction factors to the results of previous studies of the role of flares in abiogenesis. Our results show that M stars do not need to be as active as previously thought in order to provide the NUV flux required for prebiotic chemistry, however we note that flares will also provide more FUV flux than previously modelled.
description: 20 pages, 9 figures, 4 tables. Accepted for publication in the Monthly Notices of the Royal Astronomical Society
Конец философии или её возрождение?
Creators: name: Гуревич Павел Семёнович
Publisher: name: Философская школа
Year: 2017
Subjects: ФИЛОСОФИЯ
НАУКА
ЧЕЛОВЕК
МЕТАФИЗИКА
ТЕХНОКРАТ
ЛЮБОМУДР
УНИВЕРСАЛЬНАЯ ПРОБЛЕМА
ВЕЧНАЯ ФИЛОСОФИЯ
ВОЗРОЖДЕНИЕ ФИЛОСОФИИ
СТАТУС ФИЛОСОФСКОЙ АНТРОПОЛОГИИ
PHILOSOPHY
SCIENCE
PERSON
METAPHYSICS
TECHNOCRAT
PHILOSOPHER
UNIVERSAL PROBLEM
ETERNAL PHILOSOPHY
REVIVAL OF PHILOSOPHY
STATUS OF PHILOSOPHICAL ANTHROPOLOGY

description: В статье представлена проблема незаменимости философии в человеческом познании. Философия рассматривается как предостережение от необдуманных и опасных экспериментов, способных изменить и сам облик человека и природу человеческого рода. Только мудрец способен предостеречь человечество от посягательства на таинство жизни и смерти. Только философ благодаря своему признанию обязан представить на суд специалистов древние интуитивные предостережения, результаты огромной интеллектуальной работы мыслителей, толкующих о загадках жизни и смерти. Лишь философу надлежит придать проблеме обострённое метафизическое звучание. Проводится демаркационная линия между философией и наукой. При этом философия определяется как специфическая, глубоко личностная и уникальная форма постижения мира, которая пытается ответить на коренные вопросы человеческого существования, раскрыть общие принципы жизни универсума.Review. The article describes the problem of indispensability of philosophy in human knowledge. The philosophy is considered as caution from the rash and dangerous experiments that could change both shape of the person and the nature of the human race. Only the wise man is able to warn mankind against infringement of a sacrament of life and death. Only the philosopher thanks to the recognition is obliged to present ancient intuitive cautions, results of huge intellectual work of the thinkers interpreting riddles of life and death on court of experts. Only the philosopher should give the aggravated metaphysical sounding to a problem. The demarkation line between philosophy and science is drawn. At the same time the philosophy is defined as specific, deeply personal and unique form of comprehension of the world which tries to answer radical questions of human existence, to disclose the general principles of life of a universum.