cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Variational formulation of particle algorithms for kinetic plasma simulations
Creators: name: Evstatiev, E. G.
name: Shadwick, B. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Common time-explicit numerical methods for kinetic simulations of plasmas in the low-collisions limit fall into two classes of algorithms: momentum conserving and energy conserving. Each has certain drawbacks. The PIC algorithm does not conserve total energy, which may lead to spurious numerical heating (grid heating). Its overall accuracy is at most second due to the nature of the force interpolation between grid and particle position. Energy-conserving algorithms do not exhibit grid heating, but because their formulation uses potentials, computationally undesirable matrix inversions may be necessary. In addition, compared to PIC algorithms for the same accuracy, these algorithms have higher numerical noise due to the restricted choice of particle shapes. Here we formulate time-explicit, finite-size particle algorithms using particular reductions of the particle distribution function. These reductions are used in two variational principles, a Lagrangian-based and a Hamiltonian-based in conjunction with a non-canonical Poisson bracket. The Lagrangian formulations here generalize previous such formulations. The Hamiltonian formulation is presented here for the first time. Many drawbacks of the two classes of particle methods are mitigated. For example, restrictions on particle shapes are relaxed in energy conserving algorithms, which allows to decrease the numerical noise in these methods. The Hamiltonian formulation of particle algorithms is done in terms of fields instead of potentials, thus avoiding solving Poisson's equation. An algorithm that conserves both energy and momentum is presented. Other features of the algorithms include a natural way to perform coordinate transformations, the use of various time integrating methods, and the ability to increase the overall accuracy beyond second order, including all generalizations.
Cas9-expressing chickens and pigs as resources for genome editing in livestock
Creators: name: Rieblinger, Beate
name: Sid, Hicham
name: Duda, Denise
name: Bozoglu, Tarik
name: Klinger, Romina
name: Schlickenrieder, Antonina
name: Lengyel, Kamila
name: Flisikowski, Krzysztof
name: Hagag, Ibrahim T.
name: Kaufer, Benedikt B.
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Cas9 transgenic chicken
subject: Cas9 transgenic pig
subject: in vivo genome editing
subject: CRISPR-Cas9
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Genetically modified animals continue to provide important insights into the molecular basis of health and disease. Research has focused mostly on genetically modified mice, although other species like pigs resemble the human physiology more closely. In addition, cross-species comparisons with phylogenetically distant species such as chickens provide powerful insights into fundamental biological and biomedical processes. One of the most versatile genetic methods applicable across species is CRISPR-Cas9. Here, we report the generation of transgenic chickens and pigs that constitutively express Cas9 in all organs. These animals are healthy and fertile. Functionality of Cas9 was confirmed in both species for a number of different target genes, for a variety of cell types and in vivo by targeted gene disruption in lymphocytes and the developing brain, and by precise excision of a 12.7-kb DNA fragment in the heart. The Cas9 transgenic animals will provide a powerful resource for in vivo genome editing for both agricultural and translational biomedical research, and will facilitate reverse genetics as well as cross-species comparisons.
Minimal surfaces with positive genus and finite total curvature in $\mathbb{H}^2 \times \mathbb{R}$
Creators: name: Martin, Francisco
name: Mazzeo, Rafe
name: Rodriguez, M. Magdalena
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A10, 49Q05, 49Q10

description: We construct the first examples of complete, properly embedded minimal surfaces in $\mathbb{H}^2 \times \mathbb{R}$ with finite total curvature and positive genus. These are constructed by gluing copies of horizontal catenoids or other nondegenerate summands. We also establish that every horizontal catenoid is nondegenerate. Finally, using the same techniques, we are able to produce properly embedded minimal surfaces with infinitely many ends. Each annular end has finite total curvature and is asymptotic to a vertical totally geodesic plane.
description: 32 pages, 4 figures. This revised version will appear in Geometry and Topology
Similarities and Differences among Protein Dynamics Studied by Variable Temperature Nuclear Magnetic Resonance Relaxation
Creators: name: Busi, Baptiste
name: Yarava, Jayasubba Reddy
name: Bertarello, Andrea
name: Freymond, Francois
name: Adamski, Wiktor
name: Maurin, Damien
name: Hiller, Matthias
name: Oschkinat, Hartmut
name: Blackledge, Martin
name: Emsley, Lyndon
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Peptides and proteins
subject: Activation energy
subject: Monomers
subject: Protein dynamics
subject: Solvents
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Understanding and describing the dynamics of proteins is one of the major challenges in biology. Here, we use multifield variable-temperature NMR longitudinal relaxation (R-1) measurements to determine the hierarchical activation energies of motions of four different proteins: two small globular proteins (GB1 and the SH3 domain of alpha-spectrin), an intrinsically disordered protein (the C-terminus of the nucleoprotein of the Sendai virus, Sendai Ntail), and an outer membrane protein (OmpG). The activation energies map the motions occurring in the side chains, in the backbone, and in the hydration shells of the proteins. We were able to identify similarities and differences in the average motions of the proteins. We find that the NMR relaxation properties of the four proteins do share similar features. The data characterizing average backbone motions are found to be very similar, the same for methyl group rotations, and similar activation energies are measured. The main observed difference occurs for the intrinsically disordered Sendai Ntail, where we observe much lower energy of activation for motions of protons associated with the protein-solvent interface as compared to the others. We also observe variability between the proteins regarding side chain N-15 relaxation of lysine residues, with a higher activation energy observed in OmpG. This hints at strong interactions with negatively charged lipids in the bilayer and provides a possible mechanistic clue for the "positive-inside" rule for helical membrane proteins. Overall, these observations refine the understanding of the similarities and differences between hierarchical dynamics in proteins.
An alternative hypothesis on the origin of the Greek alphabet
Creators: name: Pennacchietti, Fabrizio A.
Publisher: name: Kervan. International Journal of African and Asian Studies
Year: 2023

description: Did the Greeks learn the alphabet directly from the Phoenicians or did they learn it from non-Semitic intermediaries? Were these intermediaries the Phrygians or did the Phrygians learn it from the Greeks or some other people? Discussing the form taken by certain Phoenician letters in the Greek and Phrygian alphabets, this article raises the hypothesis that the current forms of these two alphabets emerged for the first time in Cilicia Pedias towards the end of the 9th century BC at the chancery of the Achaean kingdom that had settled there. They were the first “Westerners” to master the Phoenician alphabet. From there, the alphabet, which by then had become consonantal and vocalic, would have spread to Phrygia through Cappadocia, and then to the peoples of the Mediterranean coast of Anatolia through Cilicia Trachea.
description: Kervan. International Journal of African and Asian Studies, V. 27 N. 1 (2023): Kervan 27, 2023
R. Zehetmayer, Kloster und Gericht. Die Entwicklung der klösterlichen Gerichtsrechte und Gerichtsbarkeit im 13. Jahrhundert unter besonderer Berücksichtigung der Zisterze Zwettl, 2001
Creators: name: Falkenstein, L.
Publisher: name: Francia
Year: 2019

description: Francia, Bd. 32 Nr. 1 (2005)
Which Analysis Approach Is Adequate to Leverage Clinical Microdialysis Data? A Quantitative Comparison to Investigate Exposure and Reponse Exemplified by Levofloxacin
Creators: name: Busse, David
name: Schaeftlein, André
name: Solms, Alexander
name: Ilia, Luis
name: Michelet, Robin
name: Zeitlinger, Markus
name: Huisinga, Wilhelm
name: Kloft, Charlotte
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: levofloxacin
subject: microdialysis
subject: noncompartmental analysis
subject: nonlinear mixed-effects modelling
subject: probability of target-attainment
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Purpose Systematic comparison of analysis methods of clinical microdialysis data for impact on target-site drug exposure and response. Methods 39 individuals received a 500 mg levofloxacin short-term infusion followed by 24-h dense sampling in plasma and microdialysate collection in interstitial space fluid (ISF). ISF concentrations were leveraged using non-compartmental (NCA) and compartmental analysis (CA) via (ii) relative recovery correction at midpoint of the collection interval (midpoint-NCA, midpoint-CA) and (ii) dialysate-based integrals of time (integral-CA). Exposure and adequacy of community-acquired pneumonia (CAP) therapy via pharmacokinetic/pharmacodynamic target-attainment (PTA) analysis were compared between approaches. Results Individual AUCISF estimates strongly varied for midpoint-NCA and midpoint-CA (≥52.3%CV) versus integral-CA (≤32.9%CV) owing to separation of variability in PK parameters (midpoint-CA = 46.5%–143%CVPK, integral-CA = 26.4%–72.6%CVPK) from recovery-related variability only in integral-CA (41.0%–50.3%CVrecovery). This also led to increased variability of AUCplasma for midpoint-CA (56.0%CV) versus midpoint-NCA and integral-CA (≤33.0%CV), and inaccuracy of predictive model performance of midpoint-CA in plasma (visual predictive check). PTA analysis translated into 33% of evaluated patient cases being at risk of incorrectly rejecting recommended dosing regimens at CAP-related epidemiological cut-off values. Conclusions Integral-CA proved most appropriate to characterise clinical pharmacokinetics- and microdialysis-related variability. Employing this knowledge will improve the understanding of drug target-site PK for therapeutic decision-making.
The appeal of subjugation: Artistic evidence of Pharaoh’s propaganda in the southern Levant during the 18th–20th Dynasties
Creators: name: Tucci, Giulia
Publisher: name: Kervan. International Journal of African and Asian Studies
Year: 2023

description: The article proposes an interpretative revisitation of a rather well-known and widespread iconographic motif in Egyptian art: the depiction of the Pharaoh striking his enemies. The scenes of subjugation constitute a red thread that connects all pharaonic dynasties, with an obvious propagandistic purpose to benefit the power of the Pharaoh, and more extensively of the imposition of Egyptian order against the chaos created by everything outside the empire, reason to take foreigners prisoners and therefore punished. The analysis develops on the double strand of monumental art and glyptic media, with a comparison of the diffusion of the two media and an in-depth study of scarabs dated between the 18th and 20th Dynasty found in the southern Levant.
description: Kervan. International Journal of African and Asian Studies, V. 27 N. 1 (2023): Kervan 27, 2023
The Importance of Being Rigid: D6-Brane Model Building on T6/Z2xZ6' with Discrete Torsion
Creators: name: Honecker, Gabriele
name: Ripka, Martin
name: Staessens, Wieland
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Model building with rigid D6-branes on the Type IIA orientifold on T6/Z2xZ6' with discrete torsion is considered. The systematic search for models of particle physics is significantly reduced by proving new symmetries among different lattice orientations. Suitable rigid D6-branes without matter in adjoint and symmetric representations are classified, and SO(2N) and USp(2N) gauge factors on orientifold invariant D6-branes are distinguished in terms of their discrete Wilson line and displacement parameters. Constraints on the non-existence of exotic matter prohibit global completions of local MSSM and left-right symmetric models, while globally defined supersymmetric Pati-Salam models are found. For the latter, only one particle generation possesses perturbative Yukawa couplings. Masses for the mild amount of exotic matter and the role of Abelian symmetries are briefly discussed. Last but not least, it is shown that for all three two-torus volumes of about the same order of magnitude, gauge coupling unification at one-loop can be achieved, while for highly unisotropic choices a low string scale in the TeV range is compatible with the observed strengths of gauge and gravitational couplings.
description: v2: typos corrected, references added, version accepted by Nucl. Phys. B; v1: 1+86 pages
Zwitterionic Character and Lipid Composition Determine the Behaviour of Glycosylphosphatidylinositol Fragments in Monolayers
Creators: name: Malik, Ankita
name: Seeberger, Peter H.
name: Brezesinski, Gerald
name: Varon Silva, Daniel
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: glycosylphosphatidylinositol
subject: monolayers
subject: glycolipids
subject: GPI modifications
subject: lipids
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Glycosylphosphatidylinositols (GPIs) are complex glycolipids found in free form or anchoring proteins to the outer leaflet of the cell membrane in eukaryotes. GPIs have been associated with the formation of lipid rafts and protein sorting on membranes. The presence of a conserved glycan core with cell-specific modifications together with lipid remodelling during biosynthesis suggest that the properties of the glycolipids are being fine-tuned. We synthesized a series of GPI fragments and evaluated the interactions and arrangement of these glycolipids in monolayers as a 2-D membrane model. GIXD and IRRAS analyses showed the need of N-acetylglucosamine deacetylation for the formation of hydrogen bonds to obtain highly structured domains in the monolayers and an effect of the unsaturated lipids in formation and localization of the glycolipids within or between membrane microdomains. These results contribute to understand the role of these glycolipids and their modifications in the organization of membranes.
Zel'dovich approximation and General Relativity
Creators: name: Rampf, Cornelius
name: Rigopoulos, Gerasimos
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show how the Zel'dovich approximation and the second order displacement field of Lagrangian perturbation theory can be obtained from a general relativistic gradient expansion in ΛCDM cosmology. The displacement field arises as a result of a second order non-local coordinate transformation which brings the synchronous/comoving metric into a Newtonian form. We find that, with a small modification, the Zel'dovich approximation holds even on scales comparable to the horizon. The corresponding density perturbation is not related to the Newtonian potential via the usual Poisson equation but via a modified Helmholtz equation. This is a consequence of causality not present in the Newtonian theory. The second order displacement field receives relativistic corrections that are subdominant on short scales but are comparable to the second order Newtonian result on scales approaching the horizon. The corrections are easy to include when setting up initial conditions in large N-body simulations.
description: 5 pages, corrected a typo, accepted for publication in MNRAS Letters
Variational properties of value functions
Creators: name: Aravkin, Aleksandr Y.
name: Burke, James V.
name: Friedlander, Michael P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: Regularization plays a key role in a variety of optimization formulations of inverse problems. A recurring theme in regularization approaches is the selection of regularization parameters, and their effect on the solution and on the optimal value of the optimization problem. The sensitivity of the value function to the regularization parameter can be linked directly to the Lagrange multipliers. This paper characterizes the variational properties of the value functions for a broad class of convex formulations, which are not all covered by standard Lagrange multiplier theory. An inverse function theorem is given that links the value functions of different regularization formulations (not necessarily convex). These results have implications for the selection of regularization parameters, and the development of specialized algorithms. Numerical examples illustrate the theoretical results.
description: 30 pages
Neutron Scattering Study of URu$_{2-x}$Re$_x$Si$_2$ with $x$ = 0.10: Driving Order towards Quantum Criticality
Creators: name: Williams, T. J.
name: Yamani, Z.
name: Butch, N. P.
name: Luke, G. M.
name: Maple, M. B.
name: Buyers, W. J. L.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report inelastic neutron scattering measurements in the hidden order state of URu$_{2-x}$Re$_x$Si$_2$ with $x$ = 0.10. We observe that towards the ferromagnetic quantum critical point induced by the negative chemical pressure of Re-doping, the gapped incommensurate fluctuations are robust and comparable in intensity to the parent material. As the Re doping moves the system toward the quantum critical point, the commensurate spin fluctuations related to hidden order weaken, display a shortened lifetime and slow down. Halfway to the quantum critical point, the hidden order phase survives, albeit weakened, in contrast to its destruction by hydrostatic pressure and by positive chemical pressure from Rh-doping.
description: 5 pages, 6 figures, 24 references
"Of madness and sagacity:" An intercultural dialogue between masks in Luigi Pirandello‘s and Penina Muhando’s plays (Part 1)
Creators: name: Nicolini, Cristina
Publisher: name: Kervan. International Journal of African and Asian Studies
Year: 2023

description: This paper stems from the challenge of translating Pirandello’s plays into Swahili and is aimed to open up a polylogue between Italian and Swahili literature. Therefore, in searching for connections between Luigi Pirandello’s and Penina Muhando’s plays, this paper will explore multiple masks engaged in a reciprocal dialogue among the following six selected plays: Enrico IV (‘Henry IV,’ Pirandello 1921); Così è, Se vi pare (‘It is so, if you think so!’ Pirandello 1917); Il Berretto a Sonagli (‘Cap and bells,’ Pirandello 1916); Pambo (‘Decoration,’ Muhando 1975); Nguzo mama (‘The Mother Pillar,’ Muhando 1982); and Lina ubani (‘An Antidote to Rot,’ Muhando 1984). In conclusion, this study will illustrate how different forms of sociohistorical alienation, which encircle the twentieth century, are stylistically represented in these plays through the characters who wear the masks of madness, or ‘sage-madness.’ To allow an in-depth analysis of the plays this study will be divided into two parts. Part one will examine Enrico IV (‘Henry IV,’ Pirandello 1921) and Pambo (‘Decoration,’ Muhando 1975). Part Two will examine Così è, Se vi pare (‘It is so, if you think so!’ Pirandello 1917); Nguzo mama (‘The Mother Pillar,’ Muhando 1982); Il Berretto a Sonagli (‘Cap and bells,’ Pirandello 1916); and Lina ubani (‘An Antidote to Rot,’ Muhando 1984).
description: Kervan. International Journal of African and Asian Studies, V. 27 N. 1 (2023): Kervan 27, 2023
Seismicity during and after stimulation of a 6.1 km deep enhanced geothermal system in Helsinki, Finland
Creators: name: Leonhardt, Maria
name: Kwiatek, Grzegorz
name: Martínez-Garzón, Patricia
name: Bohnhoff, Marco
name: Saarno, Tero
name: Heikkinen, Pekka
name: Dresen, Georg
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: stress inversion
subject: focal mechanisms
subject: fluid injection
subject: simplex-method
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::550 Geowissenschaften

description: In this study, we present a high-resolution dataset of seismicity framing the stimulation campaign of a 6.1 km deep enhanced geothermal system (EGS) in the Helsinki suburban area and discuss the complexity of fracture network development. Within the St1 Deep Heat project, 18 160 m(3) of water was injected over 49 d in summer 2018. The seismicity was monitored by a seismic network of near-surface borehole sensors framing the EGS site in combination with a multi-level geophone array located at >= 2 km of depth. We expand the original catalog of Kwiatek et al. (2019), including detected seismic events and earthquakes that occurred 2 months after the end of injection, totaling 61 163 events. We relocated events of the catalog with moment magnitudes between M-w -0.5 and M-w 1.9 using the double-difference technique and a new velocity model derived from a post-stimulation vertical seismic profiling (VSP) campaign. The analysis of the fault network development at a reservoir depth of 4.5-7 km is one primary focus of this study. To achieve this, we investigate 191 focal mechanisms of the induced seismicity using a cross-correlation-based technique. Our results indicate that seismicity occurred in three spatially separated clusters centered around the injection well. We observe a spatiotemporal migration of the seismicity during the stimulation starting from the injection well in the northwest- southeast (NW-SE) direction and in the northeast (NE) direction towards greater depth. The spatial evolution of the cumulative seismic moment, the distribution of events with M-w >= 1, and the fault plane orientations of focal mechanisms indicate an active network of at least three NW-SE- to NNW-SSE-oriented permeable zones, which is interpreted to be responsible for the migration of seismic activity away from the injection well. Fault plane solutions of the best-constrained focal mechanisms and results for the local stress field orientation indicate a reverse faulting regime and suggest that seismic slip occurred on a sub-parallel network of pre-existing weak fractures favorably oriented with the stress field, striking NNW-SEE with a dip of 45 degrees ENE parallel to the injection well.
How To Enhance Research Visibility & Citations
Creators: name: Ale Ebrahim, Nader
Publisher: name: Zenodo
Year: 2014
Subjects: H-index, Improve citations, Research tools, Bibliometrics

description: Increase your research visibility in the academic world in order to receive comments and citations from fellow researchers across the globe, is essential. Because, The number of citations contributes to over 30% in the university rankings. Therefore, most of the scientists are looking for an effective method to increase their citation record.

Publishing a high quality paper in scientific journals is only the mid point towards receiving citation in the future. The balance of the journey is completed by advertising and disseminating the publications by using the proper “Research Tools”. Nader who has developed a method for increasing the visibility of the research, will get you familiar with the tools you need in order to grow your research visibility and raise the impact of research.
description: Cite as:

Ale Ebrahim, N. (2014). How to Enhance Research Visibility & Citations. Paper presented at the Pharmacology Department Journal Club Seminar Series, Lecture Hall , Pharmacology Department, Faculty of Medicine., University of Malaya. http://works.bepress.com/aleebrahim/84/
Measurement of the Femoral Anteversion Angle in Medium and Large Dog Breeds Using Computed Tomography
Creators: name: Al Aiyan, Ahmad
name: Richardson, Ken
name: Manchi, George
name: Ginja, Mário
name: Brunnberg, Leo
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: computed tomography
subject: total hip replacement
subject: canine
subject: femoral anteversion angle
subject: femoral morphology
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: To promote the development of an optimally functional total hip prosthesis for medium and large dog breeds, accurate measurements of the normal anatomy of the proximal femur and acetabular retroversion are essential. The aim of the current study was to obtain precise normal values of the femoral anteversion angle using computed tomography on cadavers of mature dogs with normal hip joints of both medium and large breeds. Based on the length of their femora 58 dogs were allocated either to group I: <= 195 mm or group II: >195 mm. In the study the femoral anteversion angle (FAA) was measured on each femur using multi-slice spiral computed tomography (CT). The data were processed as multi-planar and three-dimensional reconstructions using Advantage Workstation software. The CT measurements showed that the mean +/- standard deviation (SD) FAA of group I was 31.34 +/- 5.47 degrees and in group II it was 31.02 +/- 4.95 degrees. There were no significant mean difference associations between the length of the femur and the femoral neck angle in either group (P > 0.05). The data suggest that a prosthesis FAA of 31 degrees would be suitable for a wide range of dog sizes.
Die frühzeitliche Monarchie und ihr Erbe. Festschrift für Heinz Duchhardt zum 60. Geburtstag, hg. von R. Asch, J. Arndt, M. Schnettger, 2003
Creators: name: Michaud, C.
Publisher: name: Francia
Year: 2019

description: Francia, Bd. 32 Nr. 2 (2005)
Worldsheet Form Factors in AdS/CFT
Creators: name: Klose, Thomas
name: McLoughlin, Tristan
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We formulate a set of consistency conditions appropriate to worldsheet form factors in the massive, integrable but non-relativistic, light-cone gauge fixed AdS(5) x S**5 string theory. We then perturbatively verify that these conditions hold, at tree level in the near-plane-wave limit and to one loop in the near-flat (Maldacena-Swanson) limit, for a number of specific cases. We further study the form factors in the weakly coupled dual description, verifying that the relevant conditions naturally hold for the one-loop Heisenberg spin-chain. Finally, we note that the near-plane-wave expressions for the form factors, when further expanded in small momentum or, equivalently, large charge density, reproduce the thermodynamic limit of the spin-chain results at leading order.
description: 30 pages, 12 figures, v3: typos fixed, improved discussion of bound states and bound state axiom
Diversity of methicillin-resistant coagulase-negative Staphylococcus spp. and methicillin-resistant Mammaliicoccus spp. isolated from ruminants and New World camelids
Creators: name: Schauer, B.
name: Szostak, M. P.
name: Ehricht, R.
name: Monecke, S.
name: Feßler, Andrea T.
name: Schwarz, Stefan
name: Spergser, J.
name: Krametter-Frotscher, R.
name: Loncaric, I.
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Coagulase-negative
subject: Staphylococcus spp
subject: Mammaliicoccus spp
subject: Mammaliicoccus sciuri group
subject: Methicillin-resistance
subject: Ruminants
subject: New World camelids
subject: MLST
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Information about livestock carrying methicillin-resistant coagulase-negative staphylococci and mammaliicocci (MRCoNS/MRM) is scarce. The study was designed to gain knowledge of the prevalence, the phenotypic and genotypic antimicrobial resistance and the genetic diversity of MRCoNS/MRM originating from ruminants and New World camelids. In addition, a multi-locus sequence typing scheme for the characterization of Mammaliicoccus (formerly Staphylococcus) sciuri was developed. The study was conducted from April 2014 to January 2017 at the University Clinic for Ruminants and the Institute of Microbiology at the University of Veterinary Medicine Vienna. Seven hundred twenty-three nasal swabs originating from ruminants and New World camelids with and without clinical signs were examined. After isolation, MRCoNS/MRM were identified by MALDI-TOF, rpoB sequencing and typed by DNA microarray-based analysis and PCR. Antimicrobial susceptibility testing was conducted by agar disk diffusion. From all 723 nasal swabs, 189 MRCoNS/MRM were obtained. Members of the Mammaliicoccus (M.) sciuri group were predominant (M. sciuri (n = 130), followed by M. lentus (n = 43), M. fleurettii (n = 11)). In total, 158 out of 189 isolates showed phenotypically a multi-resistance profile. A seven-loci multi-locus sequence typing scheme for M. sciuri was developed. The scheme includes the analysis of internal segments of the house-keeping genes ack, aroE, ftsZ, glpK, gmk, pta1 and tpiA. In total, 28 different sequence types (STs) were identified among 92 selected M. sciuri isolates. ST1 was the most prevalent ST (n = 35), followed by ST 2 (n = 15), ST3 and ST5 (each n = 5), ST4 (n = 3), ST6, ST7, ST8, ST9, ST10 and ST11 (each n = 2).
N=1 superconformal blocks with Ramond fields from AGT correspondence
Creators: name: Belavin, Alexander
name: Mukhametzhanov, Baur
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We use AGT correspondence between N=2 SUSY Yang-Mills theory on ${\mathbb R}^4/{\mathbb Z}_2$ and two-dimensional CFT model with the algebra $ {\cal H} \oplus \hat{sl}(2)_2 \oplus \text{NSR}$ to obtain the explicit expressions for 4-point NSR conformal blocks including Ramond fields in terms of Nekrasov partition functions and correlation functions of $\hat{sl}(2)_2$ WZW model.
description: a reference corrected, version for JHEP
Hyperbranched Rigid Aromatic Phosphorus-Containing Flame Retardants for Epoxy Resins
Creators: name: Battig, Alexander
name: Müller, Patrick
name: Bertin, Annabelle
name: Schartel, Bernhard
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: DOPO
subject: epoxy resins
subject: flame retardant
subject: hyperbranched polymers
subject: phosphine oxide
subject: phosphorus
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: A rigid aromatic phosphorus-containing hyperbranched flame retardant structure is synthesized from 10-(2,5-dihydroxyphenyl)-10H-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO-HQ), tris(4-hydroxyphenyl)phosphine oxide (THPPO), and 1,4-terephthaloyl chloride (TPC). The resulting poly-(DOPO-HQ/THPPO-terephthalate) (PDTT) is implemented as a flame retardant into an epoxy resin (EP) at a 10 wt% loading. The effects on EP are compared with those of the monomer DOPO-HQ and triphenylphosphine oxide (OPPh3) as low molar mass flame retardants. The glass transition temperature, thermal decomposition, flammability (reaction to small flame), and burning behavior of the thermosets are investigated using differential scanning calorimetry, thermogravimetric analysis, pyrolysis combustion flow calorimetry, UL 94-burning chamber testing, and cone calorimeter measurements. Although P-contents are low at only 0.6 wt%, the study aims not at attaining V-0, but at presenting a proof of principle: Epoxy resinswith PDTT show promising fire performance, exhibiting a 25% reduction in total heat evolved (THE), a 30% reduction in peak heat release rate (PHRR) due to flame inhibition (21% reduction in effective heat of combustion (EHC)), and an increase in T-g at the same time. This study indicates that rigid aromatic hyperbranched polymeric structures offer a promising route toward multifunctional flame retardancy.
Kussummiya phonology
Creators: name: Tesfaye, Wondwosen
Publisher: name: Kervan. International Journal of African and Asian Studies
Year: 2023

description: The article provides a descriptive account of the phonology of Kussummiya spoken in southwest Ethiopia. It is basically a qualitative study in that linguistic data are collected from native speakers by using elicitation technique. The collected data are organized and analyzed categorically. The findings of the study show that Kussummiya has 21 attested consonant phonemes and five short and five long vowel phonemes which is a typical feature of Cushitic vowel system. All consonant phonemes geminate and they occur only in word medial position. Consonant gemination and vowel length are phonemic. Consonant cluster occur in word medial position with a maximum of two non-identical consonants. Some of the phonological processes identified in words or across words are: insertion, deletion, devoicing, spirantisation, assimilation and metathesis.
description: Kervan. International Journal of African and Asian Studies, V. 27 N. 1 (2023): Kervan 27, 2023
Guerres et paix en Europe centrale aux époques moderne et contemporaine. Mélanges d'histoire des relations internationales offerts à Jean Bérenger. Textes réunis par D. Tollet avec une introduction de L. Bély, 2003
Creators: name: Externbrink, S.
Publisher: name: Francia
Year: 2019

description: Francia, Bd. 32 Nr. 2 (2005)
Conformal holonomy, symmetric spaces, and skew symmetric torsion
Creators: name: Alt, Jesse
name: Di Scala, Antonio J.
name: Leistner, Thomas
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A30, 53C29 (Primary) 53C35, 53C50 (Secondary)

description: We consider the question: can the isotropy representation of an irreducible pseudo-Riemannian symmetric space be realized as a conformal holonomy group? Using recent results of Cap, Gover and Hammerl, we study the representations of SO(2,1), PSU(2,1) and PSp(2,1) as isotropy groups of irreducible symmetric spaces of signature (3,2), (4,4) and (6,8), respectively, describing the geometry induced by a conformal holonomy reduction to the corresponding subgroups. In the case of SO(2,1) we show that conformal manifolds with such a holonomy reduction are always locally conformally flat and hence this group cannot be a conformal holonomy group. This result completes the classification of irreducible conformal holonomy groups in Lorentzian signature. In the case of PSU(2,1), we show that conformal manifolds of signature (3,3) with this holonomy reduction carry, on an open dense subset, a canonical nearly para-Kaehler metric with positive Einstein constant. For PSp(2,1) we also show that there is an open dense subset endowed with a canonical Einstein metric in the conformal class. As a result, after restricting to an open dense subset the conformal holonomy must be a proper subgroup of PSU(2,1) or of PSp(2,1), respectively. Finally, using a recent result of Graham and Willse we prove the following general non-existence result: for a real-analytic, odd-dimensional conformal manifold, the conformal holonomy group can never be given by the isotropy representation of an irreducible pseudo-Riemannian symmetric space unless the isotropy is SO(p+1,q+1).
description: 39 pages, comments welcome. In version 2 the statement of Theorem 2 is corrected, see also Remark 4 on page 24. In version 3, the technical Lemma 6 in the appendix is changed, typos are corrected and acknowledgements added
Transfer learning for ECG classification
Creators: name: Weimann, Kuba
name: Conrad, Tim O. F.
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: computational biology
subject: bioinformatics
subject: machine learning
subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::000 Informatik, Informationswissenschaft, allgemeine Werke

description: Remote monitoring devices, which can be worn or implanted, have enabled a more effective healthcare for patients with periodic heart arrhythmia due to their ability to constantly monitor heart activity. However, these devices record considerable amounts of electrocardiogram (ECG) data that needs to be interpreted by physicians. Therefore, there is a growing need to develop reliable methods for automatic ECG interpretation to assist the physicians. Here, we use deep convolutional neural networks (CNN) to classify raw ECG recordings. However, training CNNs for ECG classification often requires a large number of annotated samples, which are expensive to acquire. In this work, we tackle this problem by using transfer learning. First, we pretrain CNNs on the largest public data set of continuous raw ECG signals. Next, we finetune the networks on a small data set for classification of Atrial Fibrillation, which is the most common heart arrhythmia. We show that pretraining improves the performance of CNNs on the target task by up to 6.57%, effectively reducing the number of annotations required to achieve the same performance as CNNs that are not pretrained. We investigate both supervised as well as unsupervised pretraining approaches, which we believe will increase in relevance, since they do not rely on the expensive ECG annotations. The code is available on GitHub at https://github.com/kweimann/ecg-transfer-learning.
D-brane instantons on non-Spin cycles
Creators: name: Berglund, Per
name: García-Etxebarria, Iñaki
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We show that non-Spin cycles in type IIB Calabi-Yau orientifold compactifications with vanishing B field naturally support orientifold-invariant D-brane instantons. These instantons, associated to the holomorphic cotangent bundle of the non-Spin cycle, can lead to non-perturbative corrections to the superpotential.
description: 10 pages. v3: version to appear in JHEP
Structure‐based identification of dual ligands at the A2AR and PDE10A with anti‐proliferative effects in lung cancer cell‐lines
Creators: name: Kalash, Leen
name: Winfield, Ian
name: Safitri, Dewi
name: Bermudez, Marcel
name: Carvalho, Sabrina
name: Glen, Robert
name: Ladds, Graham
name: Bender, Andreas
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: Docking
subject: MD simulations
subject: Structure‐based design
subject: Virtual screening
subject: A2AR
subject: PDE10A
subject: Anti‐proliferative
subject: Dual target
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Enhanced/prolonged cAMP signalling has been suggested as a suppressor of cancer proliferation. Interestingly, two key modulators that elevate cAMP, the A2A receptor (A2AR) and phosphodiesterase 10A (PDE10A), are differentially co-expressed in various types of non-small lung cancer (NSCLC) cell-lines. Thus, finding dual-target compounds, which are simultaneously agonists at the A2AR whilst also inhibiting PDE10A, could be a novel anti-proliferative approach. Using ligand- and structure-based modelling combined with MD simulations (which identified Val84 displacement as a novel conformational descriptor of A2AR activation), a series of known PDE10A inhibitors were shown to dock to the orthosteric site of the A2AR. Subsequent in-vitro analysis confirmed that these compounds bind to the A2AR and exhibit dual-activity at both the A2AR and PDE10A. Furthermore, many of the compounds exhibited promising anti-proliferative effects upon NSCLC cell-lines, which directly correlated with the expression of both PDE10A and the A2AR. Thus, we propose a structure-based methodology, which has been validated in in-vitro binding and functional assays, and demonstrated a promising therapeutic value.
Topological Rényi entropy after a quantum quench
Creators: name: Halász, Gábor B.
name: Hamma, Alioscia
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present an analytical study on the resilience of topological order after a quantum quench. The system is initially prepared in the ground state of the toric-code model, and then quenched by switching on an external magnetic field. During the subsequent time evolution, the variation in topological order is detected via the topological Renyi entropy of order 2. We consider two different quenches: the first one has an exact solution, while the second one requires perturbation theory. In both cases, we find that the long-term time average of the topological Renyi entropy in the thermodynamic limit is the same as its initial value. Based on our results, we argue that topological order is resilient against a wide range of quenches.
description: 5 pages, 4 figures, published version with structural changes, see supplemental material at http://link.aps.org/supplemental/10.1103/PhysRevLett.110.170605
Supplemental files for JDS 19563: The effects of organic grass and grass-birdsfoot trefoil pastures on Jersey heifer development: Herbage characteristics affecting intake
Creators: name: Waldron, Blair
Publisher: name: figshare
Year: 2021
Subjects: subject: 70304 Crop and Pasture Biomass and Bioproducts
subject: FOS: Agriculture, forestry and fisheries
subject: 70306 Crop and Pasture Nutrition
subject: 70202 Animal Growth and Development
subject: FOS: Animal and dairy science

description: Supplemental figures and table from J. Dairy Sci. 104: The effects of organic grass and grass-birdsfoot trefoil pastures on Jersey heifer development: Herbage characteristics affecting intake.
Fundamentals of the logarithmic measure for revealing multimodal diffusion
Creators: name: Dalton, Benjamin A.
name: Sbalzarini, Ivo F.
name: Hanasaki, Itsuo
Publisher: name: Freie Universität Berlin
Year: 2021
Subjects: subject: single-particle tracking
subject: motion
subject: behavior
subject: cell
subject: superfamily
subject: surface
subject: flow
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: We develop a theoretical foundation for a time-series analysis method suitable for revealing the spectrum of diffusion coefficients in mixed Brownian systems, for which no prior knowledge of particle distinction is required. This method is directly relevant for particle tracking in biological systems, in which diffusion processes are often nonuniform. We transform Brownian data onto the logarithmic domain, in which the coefficients for individual modes of diffusion appear as distinct spectral peaks in the probability density. We refer to the method as the logarithmic measure of diffusion, or simply as the logarithmic measure. We provide a general protocol for deriving analytical expressions for the probability densities on the logarithmic domain. The protocol is applicable for any number of spatial dimensions with any number of diffusive states. The analytical form can be fitted to data to reveal multiple diffusive modes. We validate the theoretical distributions and benchmark the accuracy and sensitivity of the method by extracting multimodal diffusion coefficients from two-dimensional Brownian simulations of polydisperse filament bundles. Bundling the filaments allows us to control the system nonuniformity and hence quantify the sensitivity of the method. By exploiting the anisotropy of the simulated filaments, we generalize the logarithmic measure to rotational diffusion. By fitting the analytical forms to simulation data, we confirm the method's theoretical foundation. An error analysis in the single-mode regime shows that the proposed method is comparable in accuracy to the standard mean-squared displacement approach for evaluating diffusion coefficients. For the case of multimodal diffusion, we compare the logarithmic measure against other, more sophisticated methods, showing that both model selectivity and extraction accuracy are comparable for small data sets. Therefore, we suggest that the logarithmic measure, as a method for multimodal diffusion coefficient extraction, is ideally suited for small data sets, a condition often confronted in the experimental context. Finally, we critically discuss the proposed benefits of the method and its information content.
Modeling of causality with metamaterials
Creators: name: Smolyaninov, Igor I.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Optics (physics.optics)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Hyperbolic metamaterials may be used to model a 2+1 dimensional Minkowski spacetime in which the role of time is played by one of the spatial coordinates. When a metamaterial is built and illuminated with a coherent extraordinary laser beam, the stationary pattern of light propagation inside the metamaterial may be treated as a collection of particle world lines, which represents a complete history of this 2+1 dimensional spacetime. While this model may be used to build interesting spacetime analogs, such as metamaterial black holes and big bang, it lacks causality: since light inside the metamaterial may propagate back and forth along the timelike spatial coordinate, events in the future may affect events in the past. Here we demonstrate that a more sophisticated metamaterial model may fix this deficiency via breaking the mirror and temporal (PT) symmetries of the original model and producing one-way propagation along the timelike spatial coordinate. Resulting 2+1 Minkowski spacetime appears to be causal. This scenario may be considered as a metamaterial model of the Wheeler-Feynman absorber theory of causality.
description: 16 pages, 4 figures, this version is accepted for publication in the Journal of Optics
Production of negative parity baryons in the holographic Sakai-Sugimoto model
Creators: name: Ballon-Bayona, Alfonso
name: Boschi-Filho, Henrique
name: Braga, Nelson R. F.
name: Ihl, Matthias
name: Torres, Marcus A. C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We extend our investigation of resonance production in the Sakai-Sugimoto model to the case of negative parity baryon resonances. Using holographic techniques we extract the generalized Dirac and Pauli baryon form factors as well as the helicity amplitudes for these baryonic states. Identifying the first negative parity resonance with the experimentally observed S_{11}(1535), we find reasonable agreement with experimental data from the JLab-CLAS collaboration. We also estimate the contribution of negative parity baryons to the proton structure functions.
description: 1+30 pages, 8 figures. v3: typos corrected, references added, section 2 and 3 shortened, improved discussion of helicity amplitudes and comparison with experimental results