cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Η αυτόματη παραγγελία στην εφοδιαστική αλυσίδα
Creators: name: Αρβανιτάκης, Ευάγγελος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Αυτοματισμός
subject: Εφοδιαστική αλυσίδα
subject: Αυτοματοποίηση διαδικασιών

description: Το εσωτερικό σύστημα εφοδιαστικής περιλαμβάνει όλες τις δραστηριότητες που σχετίζονται με τη διαχείριση της ροής των υλικών μέσα στα φυσικά όρια μιας εγκατάστασης. Ο αυτοματισμός είναι ένας πιθανός τρόπος που μπορεί να αυξήσει την ανταγωνιστικότητα ενός οργανισμού. Ωστόσο, η χρήση τέτοιων αυτοματισμών είναι επί του παρόντος περιορισμένη. Ο κύριος στόχος αυτής της εργασίας είναι να εξηγήσει την ανάπτυξη και την χρήση του αυτοματισμού μέσα σε μια εταιρεία, μέσα από την ανασκόπηση της υπάρχουσας βιβλιογραφίας και ταυτόχρονα με την ανάλυση μιας μελέτης περίπτωσης της αυτοματοποίησης της αλυσίδας εφοδιασμού του ομίλου Inditex-Zara. Υπάρχουν διάφορα μοντέλα που αναλύουν την εφοδιαστική αλυσίδα και τη διαχείριση της, οι οποίες συνέβαλλαν στην εξέλιξη και την αποτελεσματικότητα του τομέα. Έχει γίνει διεξοδική έρευνα σχετικά με τα οφέλη αλλά και τους κινδύνους που συνεπάγεται η πρόοδος και η αυτοματοποίηση του τμήματος εφοδιαστικής με χρήση προηγμένου τεχνολογικού εξοπλισμού. Με αυτόν τον τρόπο, η σημασία των αυτοματοποιημένων παραγγελιών αναδεικνύεται στο δεύτερο μέρος της εργασίας. Συνοψίζοντας, η μελέτη περίπτωσης παρουσιάζει μια πιο ξεκάθαρη εικόνα της πρακτικής χρήσης των μοντέλων αυτοματισμού στη διαχείριση της αλυσίδας εφοδιασμού.
A nested model for AI design and validation
Creators: name: Dubey, Akshat
name: Yang, Zewen
name: Hattab, Georges
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: AI design
subject: validation
subject: nested model
subject: 000 Informatik, Informationswissenschaft, allgemeine Werke::000 Informatik, Wissen, Systeme::004 Datenverarbeitung; Informatik

description: The growing AI field faces trust, transparency, fairness, and discrimination challenges. Despite the need for new regulations, there is a mismatch between regulatory science and AI, preventing a consistent framework. A five-layer nested model for AI design and validation aims to address these issues and streamline AI application design and validation, improving fairness, trust, and AI adoption. This model aligns with regulations, addresses AI practitioners’ daily challenges, and offers prescriptive guidance for determining appropriate evaluation approaches by identifying unique validity threats. We have three recommendations motivated by this model: (1) Authors should distinguish between layers when claiming contributions to clarify the specific areas in which the contribution is made and to avoid confusion; (2) authors should explicitly state upstream assumptions to ensure that the context and limitations of their AI system are clearly understood, (3) AI venues should promote thorough testing and validation of AI systems and their compliance with regulatory requirements.
Inference of proto-neutron star properties from gravitational-wave data in core-collapse supernovae
Creators: name: Bizouard, Marie-Anne
name: Maturana-Russel, Patricio
name: Torres-Forné, Alejandro
name: Obergaulinger, Martin
name: Cerdá-Durán, Pablo
name: Christensen, Nelson
name: Font, José A.
name: Meyer, Renate
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The eventual detection of gravitational waves from core-collapse supernovae (CCSN) will help improve our current understanding of the explosion mechanism of massive stars. The stochastic nature of the late post-bounce gravitational wave signal due to the non-linear dynamics of the matter involved and the large number of degrees of freedom of the phenomenon make the source parameter inference problem very challenging. In this paper we take a step towards that goal and present a parameter estimation approach which is based on the gravitational waves associated with oscillations of proto-neutron stars (PNS). Numerical simulations of CCSN have shown that buoyancy-driven g-modes are responsible for a significant fraction of the gravitational wave signal and their time-frequency evolution is linked to the physical properties of the compact remnant through universal relations, as demonstrated in [1]. We use a set of 1D CCSN simulations to build a model that relates the evolution of the PNS properties with the frequency of the dominant g-mode, which is extracted from the gravitational-wave data using a new algorithm we have developed for our study. The model is used to infer the time evolution of a combination of the mass and the radius of the PNS. The performance of the method is estimated employing simulations of 2D CCSN waveforms covering a progenitor mass range between 11 and 40 solar masses and different equations of state. Considering signals embedded in Gaussian gravitational wave detector noise, we show that it is possible to infer PNS properties for a galactic source using Advanced LIGO and Advanced Virgo data at design sensitivities. Third generation detectors such as Einstein Telescope and Cosmic Explorer will allow to test distances of ${\cal O}(100\, {\rm kpc})$.
Identified particle transverse momentum spectra in p+p and d+Au collisions at sqrt{s_NN} = 200 GeV
Creators: name: Netrakanti, Pawan Kumar
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The transverse momentum ($p_{\mathrm T}$) spectra for identified charged pions, protons and anti-protons from $p$+$p$ and $d$+Au collisions are measured around midrapidity ($\mid$y$\mid$ $
description: Talk given at Particles and Nuclei International Conference, Santa Fe,NM-October 24-28,2005
Η κερδοφορία των ευρωπαϊκών τραπεζών στην εποχή του ευρώ
Creators: name: Κλεισαρχάκη, Αθηνά
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Κερδοφορία
subject: Ευρωπαϊκό τραπεζικό σύστημα
subject: Ευρωζώνη
subject: Τράπεζες
subject: Παράγοντες κερδοφορίας

description: Το τραπεζικό σύστημα στην ευρωζώνη ειδικά μετά την κρίση του 2008 βρέθηκε στο επίκεντρο των κανονιστικών αρχών καθώς οι εξελίξεις σε αυτό αρχικά έχουν τεράστιες επιπτώσεις στην πραγματική οικονομία αλλά παράλληλα λόγω της νομισματικής ένωσης επιδρούν σε όλες τις οικονομίες των κρατών-μελών. Η αύξηση της εποπτείας και των εποπτικών μηχανισμών κρίθηκε απαραίτητη, ενώ σταδιακά επήλθε και η τραπεζική ενοποίηση. Όσον αφορά την διάρθρωση του πιστωτικού συστήματος μεταξύ των χωρών της ευρωζώνης υπάρχει μεγάλη ανομοιογένεια και βασικό χαρακτηριστικό των τελευταίων ετών είναι η αύξηση του βαθμού συγκέντρωσης και ο περιορισμός του κλάδου (σε καταστήματα, ανθρώπινο δυναμικό και τράπεζες). Στο εμπειρικό μέρος της εργασίας εξετάζεται η κερδοφορία των τραπεζών των χωρών της ευρωζώνης μετά την κρίση (και κατά τη διάρκεια για κάποιες χώρες) και συγκεκριμένα την περίοδο 2011-2018 καθώς και οι παράγοντες που την καθορίζουν. Μεταξύ των τραπεζών του δείγματος υπήρξαν μεγάλες αποκλίσεις τόσο στην κερδοφορία (που κατά μέσο όρο ήταν σε χαμηλά επίπεδα) όσο και στους υπόλοιπους δείκτες. Από την έρευνα διαπιστώνεται ότι η αύξηση της κεφαλαιακής αυτονομίας και η μεγαλύτερη επέκταση στην αγορά μιας τράπεζας από την συνολική ανάπτυξη του κλάδου δρουν ευεργετικά στα κέρδη των τραπεζών. Αντίθετα, η αύξηση των καταθέσεων, των λειτουργικών εξόδων και των προβλέψεων για ζημιές από δάνεια μειώνουν την απόδοση των κεφαλαίων.
The androgen receptor plays different roles in macrophage-induced proliferation in prostate stromal cells between transitional and peripheral zones of benign prostatic hypertrophy
Creators: name: Xu, Dongliang
name: Wang, Xingjie
name: Jiang, Chenyi
name: Ruan, Yuan
name: Xia, Shujie
name: Wang, Xiaohai
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: stromal cell
subject: macrophage
subject: androgen receptor
subject: benign prostatic hyperplasia
subject: transitional zone
subject: 610

description: Macrophages play a critical role in the process of excessive stromal proliferation of benign prostatic hyperplasia (BPH). In our previous study, we used a BPH mouse model to elucidate a potential mechanism whereby macrophage infiltration promotes stromal cell proliferation in the prostate via the androgen receptor (AR)/inflammatory cytokine CCL3-dependent pathway. In our present study, we used the co-culture system of human macrophages and various prostatic zone stromal cells to further demonstrate that infiltrating macrophages promote prostatic stromal cell proliferation through stromal AR-dependent pathways, and we show that the stroma of TZ and PZ respond to macrophages differently because of differences in stromal AR signaling; this could possibly be one of the key pathways for stromal expansion during BPH development and progression. We hypothesize that AR and different downstream inflammatory mediators between TZ and PZ could serve as potential targets for the future design of therapeutic agents for BPH and our results provide significant insights into the search for targeted therapeutic approaches to battle BPH.
description: EXCLI Journal;Vol. 16 2017
Αποτελεσματικότητα και κερδοφορία στο τραπεζικό σύστημα
Creators: name: Κοκκόσης, Ιωάννης
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Λειτουργία των τραπεζικών ιδρυμάτων
subject: Αποτελεσματικότητα των τραπεζικών ιδρυμάτων
subject: Πλαίσιο κανόνων για τα τραπεζικά ιδρύματα
subject: Κερδοφορία των τραπεζικών ιδρυμάτων

description: Στόχος της παρούσας διπλωματικής είναι η ανάλυση της κερδοφορίας των τραπεζών Alpha Bank, Eurobank, Εθνικής Tράπεζας και Τράπεζας Πειραιώς. Στην αρχή παρουσιάζονται κάποιοι ορισμοί σχετικά με τα χρηματοπιστωτικά ιδρύματα και μία σύντομη ανάλυση του ισολογισμού της τράπεζας. Η σωστή κατανόηση και ερμηνεία του ισολογισμού των τραπεζών είναι πολύ σημαντική διότι σε αυτά τα δημοσιευμένα στοιχεία απεικονίζονται οι κινήσεις που έχουν διεξαχθεί καθώς και το τελικό αποτέλεσμα (κέρδος/ ζημία). Εν συνεχεία αναλύονται τα αποτελέσματα των ισολογισμών για τις παραπάνω τράπεζες. Απεικονίζεται διαγραμματικά η κερδοφορία των τραπεζών και γίνεται επεξήγηση αυτών των αποτελεσμάτων ανάλογα με τις κινήσεις-επενδύσεις που έχουν αναλάβει. Στο επόμενο κεφάλαιο αναλύονται οι κίνδυνοι που αναλαμβάνουν οι τράπεζες λόγω της λειτουργίας τους. Η δραστηριότητα των τραπεζών ενέχει κάποιους κινδύνους και είναι σημαντικό να κατανοηθεί η φύση των κινδύνων αυτών προκειμένου να περιοριστούν (δεν είναι δυνατόν να μηδενιστούν οι κίνδυνοι. Κατόπιν περιγράφεται η λειτουργία της Βασιλείας ΙΙΙ, αφού πρώτα δίνεται μία σύντομη περιγραφή της Βασιλείας Ι και ΙΙ, και πως επηρεάζει την λειτουργία των τραπεζών. Τα μέτρα που προτείνουν συνεπάγονται κάποια κόστη για τα τραπεζικά ιδρύματα. Στόχος της διπλωματικής είναι να αξιολογηθεί αν αυτό είναι απαραίτητο για τις τράπεζες. Στη συνέχεια περιγράφονται κάποια σύντομα στοιχεία που συνθέτουν το μακροοικονομικό περιβάλλον των τραπεζών. Τέλος παρουσιάζεται το οικονομετρικό μοντέλο για να εξετάσει την σχέση των μεταβλητών που σχετίζονται με το τελικό αποτέλεσμα.
The Study of Historical Travelogues from a Digital Humanities Perspective: Experiences and New Approaches
Creators: name: Ananieva, Anna
name: Balck, Sandra
name: Möhrke, Jacob
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: historical travelogues
subject: digital humanities
subject: digital scholarly edition
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::300 Sozialwissenschaften

description: This article explores how Digital Humanities methodologies can be applied to historical travelogues and highlights the potential of these technologies to provide new insights into historical data. It summarizes the experiences acquired through various research tasks undertaken by the interdisciplinary project team “Digital Editions of Historical Travelogues” (DEHisRe), funded by the German Research Council (DFG) from 2021 to 2024. Based on an iterative case study of handwritten travel journals from the early 19th century, the authors outline the six-step “Life Cycle of Digital Editing”. This circular workflow incorporates best practices in the field while aiming to produce sustainable digital editions of historical travelogues.
Molecular cloning and characterization of protein disulfide isomerase of Brugia malayi, a human lymphatic filarial parasite
Creators: name: Verma, Pravesh
name: Doharey, Pawan Kumar
name: Yadav, Sunita
name: Omer, Ankur
name: Singh, Poonam
name: Saxena, Jitendra Kumar
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: protein disulfide isomerase
subject: Brugia malayi
subject: antifilarials
subject: homology modelling and docking
subject: 610

description: Lymphatic filariasis results in an altered lymphatic system and the abnormal enlargement of body parts, causing pain, serious disability and social stigma. Effective vaccines are still not available nowadays, drugs against the disease is required. Protein disulfide isomerase (PDI) is an essential catalyst of the endoplasmic reticulum which is involved in folding and chaperone activities in different biological systems. Here, we report the enzymatic characterization of a Brugia malayi Protein disulfide isomerase (BmPDI), which was expressed and purified from Escherichia coli BL21 (DE3). Western blotting analysis showed the recombinant BmPDI could be recognized by anti-BmPDI Rabbit serum. The rBmPDI exhibited an optimum activity at pH 8 and 40 °C. The enzyme was inhibited by aurin and PDI inhibitor. Recombinant BmPDI showed interaction with recombinant Brugia malayi calreticulin (rBmCRT). The three-dimensional model for BmPDI and BmCRT was generated by homology modelling. A total of 25 hydrogen bonds were found to be formed between two interfaces. There are 259 non-bonded contacts present in the BmPDI-BmCRT complex and 12 salt bridges were formed in the interaction.
description: EXCLI Journal;Vol. 16 2017
From regulation of cell fate decisions towards patient-specific treatments, insights from mechanistic models of signalling pathways
Creators: name: Simon, Mareike
name: Konrath, Fabian
name: Wolf, Jana
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: cell fate decisions
subject: patient-specific treatments
subject: signalling pathways
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Cell fate decisions are tightly regulated by complex signalling networks. Disturbed signalling through these networks is prominent in disease development. To elucidate pathway contributions and effects of alterations to the regulation of proliferation, quiescence, senescence, and apoptosis, computational modelling has been essential. Modelling heterogeneity on different scales was shown to be important for cell fate prediction. In recent years, personalised models capturing signalling and cell fate decisions have been developed. Of special interest is the application of these models to predict the response to drugs. In this review, we highlight examples of mathematical models of signalling pathways that regulate disease-relevant cell fate decisions on the path to develop individualised patient models for optimal treatment prediction.
Emotion recognition by fusing time synchronous and time asynchronous representations
Creators: name: Wu, Wen
name: Zhang, Chao
name: Woodland, Philip C.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In this paper, a novel two-branch neural network model structure is proposed for multimodal emotion recognition, which consists of a time synchronous branch (TSB) and a time asynchronous branch (TAB). To capture correlations between each word and its acoustic realisation, the TSB combines speech and text modalities at each input window frame and then does pooling across time to form a single embedding vector. The TAB, by contrast, provides cross-utterance information by integrating sentence text embeddings from a number of context utterances into another embedding vector. The final emotion classification uses both the TSB and the TAB embeddings. Experimental results on the IEMOCAP dataset demonstrate that the two-branch structure achieves state-of-the-art results in 4-way classification with all common test setups. When using automatic speech recognition (ASR) output instead of manually transcribed reference text, it is shown that the cross-utterance information considerably improves the robustness against ASR errors. Furthermore, by incorporating an extra class for all the other emotions, the final 5-way classification system with ASR hypotheses can be viewed as a prototype for more realistic emotion recognition systems.
Pinning of polymers and interfaces by random potentials
Creators: name: Alexander, Kenneth S.
name: Sidoravicius, Vladas
Publisher: name: arXiv
Year: 2005
Subjects: subject: Probability (math.PR)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 82D60 (Primary) 82B44, 60K35 (Secondary)

description: We consider a polymer, with monomer locations modeled by the trajectory of a Markov chain, in the presence of a potential that interacts with the polymer when it visits a particular site 0. Disorder is introduced by, for example, having the interaction vary from one monomer to another, as a constant $u$ plus i.i.d. mean-0 randomness. There is a critical value of $u$ above which the polymer is pinned, placing a positive fraction of its monomers at 0 with high probability. This critical point may differ for the quenched, annealed and deterministic cases. We show that self-averaging occurs, meaning that the quenched free energy and critical point are nonrandom, off a null set. We evaluate the critical point for a deterministic interaction ($u$ without added randomness) and establish our main result that the critical point in the quenched case is strictly smaller. We show that, for every fixed $u\in\mathbb{R}$, pinning occurs at sufficiently low temperatures. If the excursion length distribution has polynomial tails and the interaction does not have a finite exponential moment, then pinning occurs for all $u\in\mathbb{R}$ at arbitrary temperature. Our results apply to other mathematically similar situations as well, such as a directed polymer that interacts with a random potential located in a one-dimensional defect, or an interface in two dimensions interacting with a random potential along a wall.
description: Published at http://dx.doi.org/10.1214/105051606000000015 in the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
In vitro and in vivo anticancer studies of 2'-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by HDAC inhibition and cell cycle arrest
Creators: name: Pande, Aditya Narayan
name: Biswas, Subhankar
name: Reddy, Neetinkumar D.
name: Jayashree, B. S.
name: Kumar, Nitesh
name: Rao, C. Mallikarjuna
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: chalcones
subject: apoptosis
subject: cell cycle
subject: HDAC
subject: DMH
subject: colon cancer
subject: 610

description: Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2′-hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro cytotoxicity on human colon carcinoma (HCT116) and African green monkey kidney epithelial cells (Vero). Only C5 showed selective cytotoxicity against HCT116 cells. Other potent cytotoxic compounds were C1, C2 and C3. Further screening included enzyme inhibition studies on histone deacetylase (HDAC) enzyme where C1 showed lowest IC50 value (105.03 µM). Based on cytotoxicity data C1, C2 and C3 were selected for further in vitro mechanistic studies, namely apoptotic studies (Acridine or- ange/Ethidium bromide (AO/EB) and Annexin V), cell cycle analysis using propidium iodide (PI) stain and in vivo anticancer efficacy in 1,2-dimethyl hydrazine (DMH) induced colorectal carcinoma in Wistar rats. The com- pounds induced apoptosis in more than 30 % cells in AO/EB and Annexin V staining. They also showed cell cycle arrest in G2/M phase with PI staining. They showed a significant reduction in aberrant crypt foci formation and adenocarcinoma count along with a significant (p<0.05) reduction in TNF-α levels as compared to DMH control at 100 mg/kg dose. Thus, it can be concluded that the synthesized 2′-hydroxychalcones were effective against colon adenocarcinoma in in vitro and in vivo studies.
description: EXCLI Journal;Vol. 16 2017
Η προώθηση της συμπεριληπτικής εκπαίδευσης μέσω της βιώσιμης στρατηγικής ηγεσίας (εμπειρική διερεύνηση)
Creators: name: Κετικίδου, Γεωργία
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Συμπεριληπτική εκπαίδευση
subject: Ειδικές εκπαιδευτικές ανάγκες
subject: Ισότιμη εκπαίδευση
subject: Βιώσιμη / αειφορική ηγεσία
subject: Ποιοτική εκπαίδευση

description: Στο πλαίσιο της διεθνούς προσπάθειας υλοποίησης της ατζέντας του ΟΗΕ για βιώσιμη εκπαίδευση, και συγκεκριμένα με σκοπό την επίτευξη του 4ου στόχου για την προώθηση της ελεύθερης, ισότιμης και ποιοτικής εκπαίδευσης της εκπαίδευσης, προκύπτει σήμερα περισσότερο από ποτέ η ανάγκη προώθησης της συμπεριληπτικής εκπαίδευσης στις σχολικές μονάδες. Η συμπεριληπτική εκπαίδευση είναι μια νέα φιλοσοφία, που εστιάζει σε μια διαφορετική οπτική της εκπαίδευσης και αποβλέπει στον συνεχή εκσυγχρονισμό του σημερινού σχολείου. Πρόκειται για μια πρόσκληση- πρόκληση για τη δημιουργία μιας κοινότητας, που προσφέρει ίσες ευκαιρίες μάθησης, εμπνέει ασφάλεια, αποδοχή και συνεργασία και επενδύει στην ευημερία των μαθητών, ανεξαρτήτως φύλου, φυλής, έθνους, κοινωνικο-οικονομικής τάξης, νοητικής κατάστασης. Δεν εστιάζει μόνο σε ένα διαφορετικό τρόπο θέασης των πραγμάτων εντός του σχολείου, άλλα στοχεύει σε μια γενικότερη αλλαγή του κοινωνικοπολιτισμικού γίγνεσθαι, όπου καλείται το σύγχρονο σχολείο από το ατομικό μοντέλο να περάσει στο κοινωνικό μοντέλο θέασης της διαφορετικότητας, σύμφωνα με το οποίο το ίδιο το σχολείο είναι αυτό που δεν μπορεί να ανταποκριθεί στις εκπαιδευτικές ανάγκες κάθε μαθητή και κάθε μαθήτριας και όχι ίδιος ο μαθητής, λόγω της ιδιαιτερότητας του. Συνεπώς, πρόκειται για μια καινοτόμα δράση και μια αέναη διαδικασία που μέσω της μοναδικότητας και ιδιαιτερότητας του κάθε παιδιού θα στοχεύει στον συνεχή μετασχηματισμό́ της ίδιας της κοινωνίας. Βέβαια, καθοριστικό ρόλο στην προώθηση συμπεριληπτικής κουλτούρας διαδραματίζει ο σχολικός ηγέτης, ο οποίος/η οποία οφείλει να αμφισβητεί το κατεστημένο, να είναι ευέλικτος/η, να αναστοχάζεται συνεχώς σε θέματα δημοκρατικών αξιών και να είναι προσανατολισμένος/η προς την βιωσιμότητα της εκπαίδευσης, ώστε να μεταλαμπαδεύσει το όραμά του/της για συμπερίληψη στους/στις υφισταμένους/ες και να δημιουργήσει τις βάσεις για συνεχείς βελτιώσεις. Στην εργασία αυτή, μελετήθηκαν τόσο οι συμπεριληπτικές πρακτικές των διευθυντών πρωτοβάθμιας εκπαίδευσης, που εφαρμόζουν στο πλαίσιο της εκπαίδευσής τους, το κλίμα του σχολείου, τους/τις εκπαιδευτικούς-υφισταμένους τους και την κοινότητα όσο και τα βασικά εμπόδια, με τα οποία έρχονται αντιμέτωποι στην προσπάθεια τους να καλλιεργήσουν συμπεριληπτική κουλτούρα στα πλαίσια ενός βιώσιμου σχολείου. Ως μέσο συλλογής των στοιχείων χρησιμοποιήθηκε το ερωτηματολόγιο. Τα πορίσματα της έρευνας καταδεικνύουν ότι οι σύγχρονοι σχολικοί ηγέτες ανταποκρίνονται στις ανάγκες της σύγχρονης κοινωνίας, υιοθετούν το συμπεριληπτικό όραμα και προχωρούν σε μια μεγάλη ποικιλία συμπεριληπτικών πρακτικών που στοχεύουν σε βιώσιμα συμπεριληπτικά σχολεία. Ωστόσο, σε αυτή τους την προσπάθεια συναντούν πολλά εμπόδια.
"DEVELOPMENT BOX" AND SPECIAL AND DIFFERENTIAL TREATMENT FOR FOOD SECURITY OF DEVELOPING COUNTRIES: POTENTIALS, LIMITATIONS AND IMPLEMENTATION ISSUES
Creators: name: Von Braun, Joachim
name: Wobst, Peter
name: Grote, Ulrike
name: Von Braun, Joachim
name: Wobst, Peter
name: Grote, Ulrike
Publisher: name: Unknown
Year: 2002
Subjects: Food Security and Poverty

description: At the Ministerial Conference in Doha, WTO member countries acknowledged the need to further correct the prevailing restrictions and distortions in agricultural world markets. The Ministerial Declaration of Doha reaffirms the commitment of creating a fair agricultural trading system that will recognize the special needs of developing countries and foster their full integration and participation in agricultural world trade. It has been widely discussed who the winners and losers of further trade liberalization may be, considering particular country groups such as the Cairns Group or the group of Net Food Importing Developing Countries. Although many developing countries may gain from both increased access to OECD markets and the elimination of own trade barriers, the most vulnerable economies within the international trading system are likely to be left behind. Therefore, it has been argued that the current WTO negotiations have to be held under the motto of a "development round" and multiple proposals have been made towards the creation of a Development Box. In this context, our paper emphasizes the heterogeneity of developing countries as a group and the regional diversity within particular economies and puts a special focus on people rather than countries. We suggest a conceptual design of a potential Development and Food Security Box within the WTO Agreement on Agriculture that would address the most pressing issues of hunger and poverty in food-insecure, low-income countries/regions. We also suggest conceptual measures to further integrate the poorest of the poor into the existing trading system and to stimulate their economic development. Finally, we make a first attempt to identify possible actors as well as financing and implementation mechanisms for a viable Development Box that would reach beyond conventional Green Box and Special and Differential Treatment measures. We conclude that direct action for food security remains necessary. The complementary potentials of trade, finance, and political reform, and the multiplicity of instruments needed for sustainable development, including food security, are to be utilized. A rule-based Development Box that is complementary to trade liberalization in the long run is called for.
Fronto-striatal alterations correlate with apathy severity in behavioral variant frontotemporal dementia
Creators: name: Upadhyay, Neeraj
name: Spottke, Annika
name: Schneider, Anja
name: Hoffmann, Daniel C.
name: Frommann, Ingo
name: Ballarini, Tommaso
name: Fliessbach, Klaus
name: Bender, Benjamin
name: Heekeren, Hauke R.
name: Haynes, John Dylan
name: Ewers, Michael
name: Düzel, Emrah
name: Glanz, Wenzel
name: Dobisch, Laura
name: Buerger, Katharina
name: Janowitz, Daniel
name: Levin, Johannes
name: Danek, Adrian
name: Teipel, Stefan
name: Kilimann, Ingo
name: Synofzik, Matthis
name: Wilke, Carlo
name: Peters, Oliver
name: Preis, Lukas
name: Priller, Josef
name: Spruth, Eike Jakob
name: Jessen, Frank
name: Boecker, Henning
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Behavioral variant FTD
subject: Cortical thickness
subject: Resting state functional connectivity
subject: Neuropsychiatric inventory questionnaire for apathy and disinhibition
subject: Executive dysfunction
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: Structural and functional changes in cortical and subcortical regions have been reported in behavioral variant frontotemporal dementia (bvFTD), however, a multimodal approach may provide deeper insights into the neural correlates of neuropsychiatric symptoms. In this multicenter study, we measured cortical thickness (CTh) and subcortical volumes to identify structural abnormalities in 37 bvFTD patients, and 37 age- and sex-matched healthy controls. For seed regions with significant structural changes, whole-brain functional connectivity (FC) was examined in a sub-cohort of N = 22 bvFTD and N = 22 matched control subjects to detect complementary alterations in brain network organization. To explore the functional significance of the observed structural and functional deviations, correlations with clinical and neuropsychological outcomes were tested where available. Significantly decreased CTh was observed in the bvFTD group in caudal middle frontal gyrus, left pars opercularis, bilateral superior frontal and bilateral middle temporal gyrus along with subcortical volume reductions in bilateral basal ganglia, thalamus, hippocampus, and amygdala. Resting-state functional magnetic resonance imaging showed decreased FC in bvFTD between: dorsal striatum and left caudal middle frontal gyrus; putamen and fronto-parietal regions; pallidum and cerebellum. Conversely, bvFTD showed increased FC between: left middle temporal gyrus and paracingulate gyrus; caudate nucleus and insula; amygdala and parahippocampal gyrus. Additionally, cortical thickness in caudal, lateral and superior frontal regions as well as caudate nucleus volume correlated negatively with apathy severity scores of the Neuropsychiatry Inventory Questionnaire. In conclusion, multimodal structural and functional imaging indicates that fronto-striatal regions have a considerable influence on the severity of apathy in bvFTD.
Using curcumin to prevent structural and behavioral changes of medial prefrontal cortex induced by sleep deprivation in rats
Creators: name: Noorafshan, Ali
name: Karimi, Fatemeh
name: Karbalay-Doust, Saied
name: Kamali, Ali Mohammad
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: sleep deprivation
subject: mPFC
subject: curcumin
subject: stereology
subject: rat
subject: 610

description: Sleep Deprivation (SD) is known to result in a range of neurological consequences in chronically-afflicted subjects. Curcumin, a natural substance, has neuroprotective properties. This study aimed to evaluate the effects of curcumin on the medial Prefrontal Cortex (mPFC) of SD rats. Male rats were arbitrarily assigned to nine groups, including control, curcumin (100 mg/kg/day), olive oil, SD, SD+curcumin, SD+olive oil, grid, grid+curcumin, and grid+ol- ive oil groups. SD was induced by a multiplatform box containing water. After a period of 21 days, the learning and memory of the rats were tested in an eight-arm radial maze. Afterwards, their brains were evaluated using stereological methods. Concomitant treatment of curcumin during SD caused fewer errors during evaluation of the working and reference memory errors in the acquisition and retention phases. The overall volume of the mPFC, Infralimbic Cortex (ILC), Prelimbic Cortex (PLC), Anterior Cingulate Cortex (ACC) and the total number of neurons and glial cells reduced by 20 %-40 % on average in the SD animals in comparison to the control group. This indicated atrophic changes and cell loss in these areas (p < 0.01). The dendrites’ length and the number of spines per dendrite also reduced by 35 %-55 % in the SD rats compared to the ones in the control group (p < 0.01). Yet, treatment of the SD animals with curcumin prevented the atrophic changes of the mPFC, cell loss, and den- dritic changes (p < 0.05). SD induced structural changes in the mPFC and memory impairment in the rats. However, curcumin could protect their PFC.
description: EXCLI Journal;Vol. 16 2017
Aromatase inhibitory activity of 1,4-naphthoquinone derivatives and QSAR study
Creators: name: Prachayasittikul, Veda
name: Pingaew, Ratchanok
name: Worachartcheewan, Apilak
name: Sitthimonchai, Somkid
name: Nantasenamat, Chanin
name: Prachayasittikul, Supaluk
name: Ruchirawat, Somsak
name: Prachayasittikul, Virapong
Publisher: name: Technische Universität Dortmund
Year: 2017
Subjects: subject: 1,4-naphthoquinones
subject: aromatase inhibitory activity
subject: structural modification
subject: computer-aided drug design
subject: anticancer agents
subject: 610

description: A series of 2-amino(chloro)-3-chloro-1,4-naphthoquinone derivatives (1-11) were investigated for their aromatase inhibitory activities. 1,4-Naphthoquinones 1 and 4 were found to be the most potent compounds affording IC50 values 5.2 times lower than the reference drug, ketoconazole. A quantitative structure-activity relationship (QSAR) model provided good predictive performance (R2 CV = 0.9783 and RMSECV = 0.0748) and indicated mass (Mor04m and H8m), electronegativity (Mor08e), van der Waals volume (G1v) and structural information content index (SIC2) descriptors as key descriptors governing the activity. To investigate the effects of structural modifications on aromatase inhibitory activity, the model was employed to predict the activities of an additional set of 39 structurally modified compounds constructed in silico. The prediction suggested that the 2,3-disubstitution of 1,4-naphthoquinone ring with halogen atoms (i.e., Br, I and F) is the most effective modification for potent activity (1a, 1b and 1c). Importantly, compound 1b was predicted to be more potent than its parent compound 1 (11.90-fold) and the reference drug, letrozole (1.03-fold). The study suggests the 1,4-naphthoquinone derivatives as promising compounds to be further developed as a novel class of aromatase inhibitors.
description: EXCLI Journal;Vol. 16 2017
On the impact of aromatic core fluorination in hydrogen-bonded liquid crystals
Creators: name: Darweesh, Ahmed F.
name: Anders, Christian
name: Ranjitha, B. S.
name: Shanker, G.
name: Alaasar, Mohamed
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 540

description: Herein we report the impact of fluorine substitution on the liquid crystalline (LC) self-assembly of supramolecular hydrogen-bonded rod-like architectures. This was systematically investigated by introducing fluorine atom at different positions or with different numbers on the investigated supramolecules. Therefore, eight different groups of hydrogen-bonded LCs (HBLCs) were designed and synthesized in which four 4-hexyloxybenzoic acid derivatives without or with fluorine substitution were used as proton donors. The proton acceptors are fluorinated or nonfluorinated alkyloxyazopyridine derivatives. The hydrogen bond formation between the complementary components was proved using FTIR and 1H NMR spectroscopy. All HBLCs were investigated for their mesomorphic behaviour using various tools such as differential scanning calorimetry (DSC), polarized optical microscopy (POM) and X-ray diffraction (XRD). Depending on the position and number of fluorine atoms different LC phases were observed including nematic, orthogonal non-tilted smectic A (SmA) or tilted smectic C (SmC) phases in addition to an unknown X phase. Depending on the position of the fluorine substitution, it was proved from the XRD investigations that different types of cybotactic nematic phases (NCyb) are exhibited by the reported HBLCs. Because of cis–trans photoisomerization under light irradiation of the reported HBLCs, their photo responsivity was investigated in solutions as well as between the different LC phases. This report provides key insights into the structure–property relationships of HBLCs, which might be of interest for optical storage device applications.
Τρομοκρατία και ασφάλεια σε συνάρτηση με την προστασία των δικαιωμάτων του ανθρώπου στην Ευρωπαϊκή Ένωση: η εκπαίδευση ως μέσο πρόληψης του τρομοκρατικού φαινομένου
Creators: name: Καραχάλιος, Δημήτριος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Εκπαίδευση
subject: Τρομοκρατία
subject: Ανθρώπινα δικαιώματα
subject: Ασφάλεια
subject: Ευρωπαϊκή Ένωση
subject: Education
subject: Terrorism
subject: Human rights
subject: Safety
subject: European Union

description: Το φαινόμενο της τρομοκρατίας απασχολεί εδώ και αιώνες τη διεθνή κοινότητα. Από τις επιθέσεις της 11ης Σεπτεμβρίου, οπότε ήρθε στο προσκήνιο το ζήτημα της τρομοκρατίας, μέχρι και τα τρομοκρατικά χτυπήματα που συμβαίνουν στις μέρες μας, το φαινόμενο αυτό φαίνεται να αποτελεί τη σοβαρότερη απειλή για τη διεθνή ειρήνη και ασφάλεια. Από τη μια, η περιφρόνηση του δικαιώματος στη ζωή από τους τρομοκράτες και η χρήση βίας και από την άλλη η ανάγκη επιβολής μέτρων εναντίον των τρομοκρατών με σκοπό τη διαφύλαξη της ασφάλειας, παραβιάζουν κατάφορα τα ανθρώπινα δικαιώματα. Σκοπός της παρούσας εργασίας είναι να εξετάσει τη σχέση μεταξύ της διαφύλαξης της ασφάλειας και της προστασίας των ανθρωπίνων δικαιωμάτων στην ΕΕ ιδίως μετά την αύξηση των κατασταλτικών και των προληπτικών μέτρων από πλευράς της Ένωσης, η οποία έχει επιφέρει τη διατάραξη της επιθυμητής ισορροπίας ασφάλειας-δικαιωμάτων. Απόρροια αυτής της ανισορροπίας είναι η καταπάτηση των δικαιωμάτων και η παραβίαση των προσωπικών δεδομένων των Ευρωπαίων αλλά και η πυροδότηση ενός κλίματος ισλαμοφοβίας, ακροδεξιού λαϊκισμού και αντιτρομοκρατικής υστερίας. Η εργασία ερευνά, επιπλέον, τη συμβολή της εκπαίδευσης στην άμβλυνση του φαινομένου της τρομοκρατίας και τους τρόπους με τους οποίους αυτό καθίσταται εφικτό. Ιδιαίτερη έμφαση δίνεται στις εκπαιδευτικές πρωτοβουλίες της ΕΕ για την καταπολέμηση της ριζοσπαστικοποίησης.
Pairing renormalization and regularization within the local density approximation
Creators: name: Borycki, P. J.
name: Dobaczewski, J.
name: Nazarewicz, W.
name: Stoitsov, M. V.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We discuss methods used in mean-field theories to treat pairing correlations within the local density approximation. Pairing renormalization and regularization procedures are compared in spherical and deformed nuclei. Both prescriptions give fairly similar results, although the theoretical motivation, simplicity, and stability of the regularization procedure makes it a method of choice for future applications.
description: 10 pages, 8 figures, submitted to Phys. Rev. C
Assessment of the effect of tricaine (MS-222)-induced anesthesia on brain-wide neuronal activity of zebrafish (Danio rerio) larvae
Creators: name: Ohnesorge, Nils
name: Wilzopolski, Jenny
name: Steinfath, Matthias
name: Lewejohann, Lars
name: Banneke, Stefanie
name: Heinl, Céline
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: zebrafish
subject: brain
subject: nociception
subject: behavior
subject: anesthesia
subject: tricaine
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Fast and effective anesthesia is the key for refining many invasive procedures in fish and gaining reliable data. For fish as for all vertebrates, it is also required by European law to reduce pain, suffering, and distress to the unavoidable minimum in husbandry and experiments. The most often used substance to induce anesthesia in zebrafish is tricaine (MS-222). When properly prepared and dosed, tricaine causes rapid loss of mobility, balance and reaction to touch. These signs are interpreted as a stage of deep anesthesia although its effects on the central nervous system have not convincingly been shown. Therefore, it might be possible that tricaine first acts only on the periphery, resulting in a paralyzed instead of an anesthetized fish. This has severe implications for animals undergoing procedures. To investigate the effects of tricaine on the central nervous system, we used zebrafish larvae [Tg( elavl3 :H2B-GCaMP6s)] at 4 days post fertilization (dpf), expressing a calcium indicator (GCaMP6s) in all neurons, that allows monitoring and quantifying the neuronal activity. After treating larvae with 168 mg/L tricaine, a rapid loss of neuronal activity in the forebrain was observed in confocal microscopy. In contrast, only mild effects were seen in the midbrain and hindbrain. In conclusion, the different larval brain areas showed differences in the sensitivity to tricaine treatment. The effects on the central nervous system are indicative of tricaine’s anesthetic function and are consistent with behavioral observations of inactivity and unresponsiveness to touch.
Η νέα νομισματική πολιτική μετά την μεγάλη κρίση του 2008-2009: ποιοι είναι οι πιθανοί κίνδυνοι της ποσοτικής χαλάρωσης;
Creators: name: Δενελάβα, Μαρίνα Αικατερίνη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Νομισματική πολιτική
subject: Κεντρικές τράπεζες
subject: Ποσοτική χαλάρωση
subject: Επιτόκια
subject: Πληθωρισμός
subject: Ομόλογα
subject: Πρόγραμμα αγοράς περιουσιακών στοιχείων
subject: Λαϊκό QE
subject: Ευρωoμόλογο
subject: Monetary policy
subject: Central banks
subject: Quantitative easing
subject: Interest rates
subject: Inflation
subject: Bonds
subject: Asset purchase program
subject: Modern monetary theory
subject: Eurobond

description: Στην προκείμενη διπλωματική διατριβή, θα διενεργηθεί έρευνα που θέτει ως θεματική τη νομισματική πολιτική που μεταδόθηκε μετά την εκδήλωση της κρίσης του 2008-2009. Αναλυτικότερα, θα επικεντρωθεί στην εφαρμογή του προγράμματος ποσοτικής χαλάρωσης, το οποίο έδρασε ως ένα επιπρόσθετο και αντισυμβατικό – έως πρότινος – μέτρο για το Ευρωσύστημα και τις Ηνωμένες Πολιτείες. Στα ακόλουθα χωρία θα αποτυπωθεί η δομή των προγραμμάτων που θεσπίστηκαν από τις κεντρικές τράπεζες στην Ευρώπη, τις Η.Π.Α. και την Ιαπωνία, το περιεχόμενο τους και θα εξετασθούν ενδελεχώς οι επιδράσεις τους σε όλο το φάσμα της οικονομίας, όπως στοιχειοθετούνται κι ερμηνεύονται αυτές. Ιδιαίτερη μνεία θα γίνει στο πρόγραμμα ποσοτικής χαλάρωσης που ακολουθήθηκε από την Ομοσπονδιακή Τράπεζα των Η.Π.Α. και πώς αυτό αποτιμάται. Επιπροσθέτως, θα αναφερθεί κι η εναλλακτική και πιο ανθρωποκεντρική «εκδοχή» της ποσοτικής χαλάρωσης όπως προτάθηκε, θέτοντας στο επίκεντρο την κοινωνική ευημερία, πέρα από το αποτύπωμα στις χρηματαγορές αλλά και υποδεικνύοντας το ρόλο που θα πρέπει λάβουν οι κεντρικές τράπεζες στη δημιουργία χρήματος ώστε να επιτευχθεί ένας ενάρετος οικονομικός κύκλος.
Analytical expressions for the time evolution of spin systems affected by two or more interactions
Creators: name: Hempel, Günther
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 530

description: Analytical expressions for the description of the time evolution of spin systems beyond product–operator formalism (POF) can be obtained if a low-dimensional subspace of the Liouville space has been found in which the time evolution of the spin system takes place completely. This can be achieved using a procedure that consists of repeated application of the commutator of the Hamiltonian with the density operator. This iteration continues as long as the result of such a commutator operation contains a term that is linearly independent of all the operators appearing in the previous commutator operations. The coefficients of the resulting system of commutator relations can be immediately inserted into the generic propagation formulae given in this article if the system contains two, three, or four equations. In cases where the validity conditions of any of these propagation formulae are not met, the coefficients are used as intermediate steps to obtain both the Liouvillian and propagator matrices of the system. Several application examples are given where an analytical equation can be obtained for the description of the time evolution of small spin systems under the influence of two or more interactions. This procedure for finding the Liouvillian matrix is not limited to time-independent interactions. Some examples illustrate the treatment of time-dependent problems using this method.
FOOD SECURITY IN TRANSITION COUNTRIES: CONCEPTUAL ISSUES AND CROSS-COUNTRY ANALYSES
Creators: name: Wehrheim, Peter
name: Wiesmann, Doris M.
name: Wehrheim, Peter
name: Wiesmann, Doris M.
Publisher: name: Unknown
Year: 2003
Subjects: Food Security and Poverty

description: Most methodological materials and analyses of food security pertain to the classical developing countries of the world. In this paper we discuss the question what pattern of food insecurity has developed across the transition countries? And, are there specific characteristics of food insecurity in the transition economies which can be attributed to the legacy of the socialist era? We argue that various legacies from the socialist system are decisive for today's economic and social environment in which food insecurity in these countries arises and has to be tackled. We discuss how the standard conceptual framework for the analysis of food security has to be adapted to take the specific characteristics of transition countries into account. Furthermore, we investigate if these legacies explain any significant differences in food security between transition and developing countries. We concluded from the analysis that on the macro-level similar basic factors determine food insecurity in transition countries and in developing countries. However, various legacies from the socialist era explain why transition countries have patterns, levels and trends of food insecurity distinct from developing countries. For instance, socialist legacies have contributed to the disproportionate decrease of the agricultural sector in most countries in transition in the 90s, and they still influence the pattern of food supply and consumption. Micro-studies would be needed to identify more precisely which affect the legacies have on food security at the household level.
Entanglement and the Power of One Qubit
Creators: name: Datta, Animesh
name: Flammia, Steven T.
name: Caves, Carlton M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The "Power of One Qubit" refers to a computational model that has access to only one pure bit of quantum information, along with n qubits in the totally mixed state. This model, though not as powerful as a pure-state quantum computer, is capable of performing some computational tasks exponentially faster than any known classical algorithm. One such task is to estimate with fixed accuracy the normalized trace of a unitary operator that can be implemented efficiently in a quantum circuit. We show that circuits of this type generally lead to entangled states, and we investigate the amount of entanglement possible in such circuits, as measured by the multiplicative negativity. We show that the multiplicative negativity is bounded by a constant, independent of n, for all bipartite divisions of the n+1 qubits, and so becomes, when n is large, a vanishingly small fraction of the maximum possible multiplicative negativity for roughly equal divisions. This suggests that the global nature of entanglement is a more important resource for quantum computation than the magnitude of the entanglement.
description: 22 pages, 4 figures