cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Competition and Coexistence of Order Parameters in Holographic Multi-Band Superconductors
Creators: name: Cai, Rong-Gen
name: Li, Li
name: Li, Li-Fang
name: Wang, Yong-Qiang
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct a holographic multi-band superconductor model with each complex scalar field in the bulk minimally coupled to a same gauge field. Taking into account the back reaction of matter fields on the background geometry and focusing on the two band case with two scalar order parameters, we find that depending on the strength of the back reaction and the charge ratio of the two bulk scalars, five different superconducting phases exist, and three of five phases exhibit some region where both orders coexist and are thermodynamically favored. The other two superconducting phases have only one scalar order. The model exhibits rich phase structure and we construct the full diagram for the five superconducting phases. Our analysis indicates that the equivalent attractive interaction mediated by gravity between the two order parameters tends to make the coexistence of two orders much more easy rather than more difficult.
description: v2: references added
Key messages of EOSC Secretariat "Researcher engagement" activities
Creators: name: Budroni, Paolo
name: Flicker, Katharina
name: Sánchez Solís, Barbara
name: Saurugger, Bernd
Publisher: name: Zenodo
Year: 2020
Subjects: European Open Science Cloud
EOSC
EOSC Secretariat

description: As partner of the project consortium EOSCSecretariat, TU Wien is responsible for the task “researcher engagement” to discuss EOSC building processes. In order to address research communities and research institutions in a structured way, TU Wien organizes a series of workshops, interviews and consultations. As part of this initiative, there were two workshops with researchers and university networks as well as a dialogue with funding bodies and research performing organisations. The goal is learning about actual needs in current research processes as well as future needs and requirements concerning research infrastructures, services and policies. The key findings and messages of the involved participants are summarized in three “Takeaway messages”.
description: Full report of the workshops with university networks: DOI 10.5281/zenodo.3693914 Full report of workshop with researchers: DOI 10.5281/zenodo.3701194
Exploring Genetics and Social Structure
Creators: name: Bearman, Peter Shawn
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Social structure
subject: Sociology
subject: FOS: Sociology

description: Just about every week the Science Times—one of the places where science meets the public enthusiastically reported on new research findings that revealed the genetic basis for something (intelligence, voting behavior, obesity, depression, sexual behavior, religiosity, orgasms, altruism and egoism, generosity, thrift, and, of course, earwax type). Aside from the earwax, the phenomena reported to be “genetic” were largely of sociological interest. Yet sociologists were rarely discussed in these articles. Meanwhile, the prevailing sentiment of the discipline appeared to be that the emphasis on genetic expression as explanation for human behavior and social outcomes was at best undermining sociological perspectives and at worst a return of the eugenicist project of the first half of the 20th century. The two reactions—enthusiastic embrace and uncritical adoption (as represented in the Science Times) and fear and loathing (from sociologists)— appeared to be in some tension. However, thinking about it a little more, one realizes that they arise from the same source: a naive overvaluation of “genetics.”
title: Extensive Periocular Basal Cell Carcinoma (BCC)
Creators: name: Skok , Tadeja
Publisher: name: EURORAD
Year: 2022
Subjects: subject: Head & neck imaging
subject: Eyes
subject: Oncology
subject: Soft tissues / Skin
subject: CT
subject: Neoplasia
subject: Pathology
subject: Clinical Cases

description: Clinical History: A 56-year-old Caucasian woman presented with progressive worsening of vision and a recurring painless mass on the eyelids of the right eye. Ophthalmologic investigation revealed visual acuity of hand motion in the right eye and a large multilobular pigmented tumour with central ulceration and bleeding, including the upper and lower eyelids. The palpebral fissure was diminished, preventing examination of deeper tissue. She had previously undergone several excisional biopsies of a basal cell carcinoma tumour of the right eyelids in the last 15 years and two courses of radiation therapy. The patient was started on treatment with systemic therapy with vismodegib. 

description: 56 years, female
Pressure induced bcc to hcp transition in Fe: Magnetism-driven structure transformation
Creators: name: Mankovsky, S.
name: Polesya, S.
name: Ebert, H.
name: Bensch, W.
name: Mathon, O.
name: Pascarelli, S.
name: Minar, J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The pressure induced bcc to hcp transition in Fe has been investigated via ab-initio electronic structure calculations. It is found by the disordered local moment (DLM) calculations that the temperature induced spin fluctuations result in the decrease of the energy of Burgers type lattice distortions and softening of the transverse $N$-point $TA_1$ phonon mode with $[\bar{1}10]$ polarization. As a consequence, spin disorder in an system leads to the increase of the amplitude of atomic displacements. On the other hand, the exchange coupling parameters obtained in our calculations strongly decrease at large amplitude of lattice distortions. This results in a mutual interrelation of structural and magnetic degrees of freedom leading to the instability of the bcc structure under pressure at finite temperature.
IGFLR1_code.R
Creators: name: Wenjing Song
Publisher: name: figshare
Year: 2020
Subjects: subject: 111201 Cancer Cell Biology
subject: FOS: Clinical medicine
subject: 111203 Cancer Genetics

description: IGFLR1 as a Novel Prognostic Biomarker in Clear Cell Renal Cell Cancer Correlating with Immune Infiltrates
Axios/Ipsos Coronavirus Index Wave 29
Creators: name: Axios
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Changes in health in last week (3); activities in last week (4); changes in work and household over last few weeks (3); personal work or shopping experiences in past few weeks (6); risk of different activities (11); safety procedures when leaving the house (3); holiday season plans (1); federal government making economic recovery from coronavirus better or worse (1); concern about coronavirus (COVID-19) outbreak (6); better or worse at handling coronavirus pandemic compared to beginning of pandemic (6); trust in organizations/politicians to provide accurate information about coronavirus (7); trust in organizations to have your best interests (4); coronavirus testing (7); main news source (1); registered to vote (1); absentee ballot (1).
Koopman-inspired Implicit Backward Reachable Sets for Unknown Nonlinear Systems
Creators: name: Balim, Haldun
name: Aspeel, Antoine
name: Liu, Zexiang
name: Ozay, Necmiye
Publisher: name: arXiv
Year: 2023
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Koopman liftings have been successfully used to learn high dimensional linear approximations for autonomous systems for prediction purposes, or for control systems for leveraging linear control techniques to control nonlinear dynamics. In this paper, we show how learned Koopman approximations can be used for state-feedback correct-by-construction control. To this end, we introduce the Koopman over-approximation, a (possibly hybrid) lifted representation that has a simulation-like relation with the underlying dynamics. Then, we prove how successive application of controlled predecessor operation in the lifted space leads to an implicit backward reachable set for the actual dynamics. Finally, we demonstrate the approach on two nonlinear control examples with unknown dynamics.
The Potts model and chromatic functions of graphs
Creators: name: Klazar, Martin
name: Loebl, Martin
name: Moffatt, Iain
Publisher: name: arXiv
Year: 2013
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: The $U$-polynomial of Noble and Welsh is known to have intimate connections with the Potts model as well as with several important graph polynomials. For each graph $G$, $U(G)$ is equivalent to Stanley's symmetric bad colouring polynomial $XB(G)$. Moreover Sarmiento established the equivalence between $U$ and the polychromate of Brylawski. Loebl defined the $q$-dichromate $B_q(G,x,y)$ as a function of a graph $G$ and three independent variables $q,x,y$, proved that it is equal to the partition function of the Potts model with variable number of states and with a certain external field contribution, and conjectured that the $q$-dichromate is equivalent to the $U$-polynomial. He also proposed a stronger conjecture on integer partitions. The aim of this paper is two-fold. We present a construction disproving Loebl's integer partitions conjecture, and we introduce a new function $B_{r,q}(G;x,k)$ which is also equal to the partition function of the Potts model with variable number of states and with a (different) external field contribution, and we show that $B_{r,q}(G;x,k)$ is equivalent to the $U$-polynomial and to Stanley's symmetric bad colouring polynomial.
The clinical features of the overlap between COPD and asthma
Creators: name: Hardin, Megan
name: Silverman, Edwin
name: Barr, R. Graham
name: Hansel, Nadia
name: Schroeder, Joyce
name: Make, Barry
name: Crapo, James
name: Hersh, Craig
Publisher: name: Columbia University
Year: 2011
Subjects: Epidemiology

description: The coexistence of COPD and asthma is widely recognized but has not been well described. This study characterizes clinical features, spirometry, and chest CT scans of smoking subjects with both COPD and asthma. We performed a cross-sectional study comparing subjects with COPD and asthma to subjects with COPD alone in the COPDGene Study. 119 (13%) of 915 subjects with COPD reported a history of physician-diagnosed asthma. These subjects were younger (61.3 vs 64.7 years old, p = 0.0001) with lower lifetime smoking intensity (43.7 vs 55.1 pack years, p = 0.0001). More African-Americans reported a history of asthma (33.6% vs 15.6%, p < 0.0001). Subjects with COPD and asthma demonstrated worse disease-related quality of life, were more likely to have had a severe COPD exacerbation in the past year, and were more likely to experience frequent exacerbations (OR 3.55 [2.19, 5.75], p < 0.0001). Subjects with COPD and asthma demonstrated greater gas-trapping on chest CT. There were no differences in spirometry or CT measurements of emphysema or airway wall thickness. Subjects with COPD and asthma represent a relevant clinical population, with worse health-related quality of life. They experience more frequent and severe respiratory exacerbations despite younger age and reduced lifetime smoking history. Trial registration: ClinicalTrials.gov: NCT00608764
Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas
Creators: name: Hill, Jonathon
name: Anderson, Keith
name: Mastracci, Teresa
name: Kaestner, Klaus
name: Sussel, Lori
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Bioinformatics
subject: FOS: Computer and information sciences

description: The creation of a complete genome-wide map of transcription factor binding sites is essential for understanding gene regulatory networks in vivo. However, current prediction methods generally rely on statistical models that imperfectly model transcription factor binding. Generation of new prediction methods that are based on protein binding data, but do not rely on these models may improve prediction sensitivity and specificity. We propose a method for predicting transcription factor binding sites in the genome by directly mapping data generated from protein binding microarrays (PBM) to the genome and calculating a moving average of several overlapping octamers. Using this unique algorithm, we predicted binding sites for the essential pancreatic islet transcription factor Nkx2.2 in the mouse genome and confirmed >90% of the tested sites by EMSA and ChIP. Scores generated from this method more accurately predicted relative binding affinity than PWM based methods. We have also identified an alternative core sequence recognized by the Nkx2.2 homeodomain. Furthermore, we have shown that this method correctly identified binding sites in the promoters of two critical pancreatic islet β-cell genes, NeuroD1 and insulin2, that were not predicted by traditional methods. Finally, we show evidence that the algorithm can also be applied to predict binding sites for the nuclear receptor Hnf4α. PBM-mapping is an accurate method for predicting Nkx2.2 binding sites and may be widely applicable for the creation of genome-wide maps of transcription factor binding sites.
Review of Explanation and Understanding in the Human Sciences by Gurpreet Mahajan Delhi: Oxford University Press, 1992. Pp. 124
Creators: name: Mullen, Edward Joseph
Publisher: name: Columbia University
Year: 1994
Subjects: Social service

description: Gurpreet Mahajan
critically analyzes explanation and understanding in the social sciences. Her
approach is consistent with those who have historically argued for a human
science with methods distinct from those of the natural sciences. Four approaches
to scientific explanation and understanding in the social sciences are
examined. The mode associated with logical positivism, causale xplanationi,s
reviewed and found to be insufficient for the social sciences. The second
approach, reason-actioenx planationi,s among the oldest forms of explanation.
Agreeing with common sense, it is the notion that the explanation for a human
action is the reason given by the agent. Hermeneutiucn derstandinga,s originally
formulated by Dilthey and subsequently proposed by Hans-Georg Gadamer
and Paul Ricoeur, is contrasted with causal explanation as well as reasonaction
explanation. Following W. B. Gallie, Arthur C. Danto, and William
Dray, the narrative mode is discussed last. While there are several versions of
the narrative mode, Dray has proposed that an event is explained when one
can "trace the course of events by which it came about." Mahajan presents
each of these four modes as framing the object of inquiry differently and
asking qualitatively different questions. After an analysis of each of these four
modes, Mahajan, taking a relativistic stance, concludes, "Since there is no
theoretical grid from which we can view the world in itself and write its history,
we must allow points of view that offer new insights and uncover different
aspects of reality some space to exist" (p. 101).
title: Der jüngere Titurel; [1000-1099]
title: (Fragmente)
titleType: Subtitle
Creators: name: Albrecht Von Scharfenberg
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2010

description: Entstehungsort: Unbekannt. - Entstehungszeit: 14. Jahrhundert
A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency
Creators: name: White, Perrin
name: Ritzen, Martin
name: Oberfield, Sharon E.
name: Meyer-Bahlburg, Heino
name: Miller, Walter
name: Montori, Victor
name: Speiser, Phyllis
name: Azziz, Ricardo
name: Baskin, Laurence
name: Ghizzoni, Lucia
name: Hensle, Terry
name: Merke, Deborah
Publisher: name: Columbia University
Year: 2010
Subjects: Medicine

description: Steroid 21-hydroxylase deficiency accounts for about 95% of cases of congenital adrenal hyperplasia (CAH). Newborns are currently being screened for the classical forms of this disease throughout the United States and in 12 other countries. As such, it seems important to develop the best practice guidelines for treating not only infants and children, but affected adults as well. This report gives a brief overview of the most recent expert opinion and clinical practice guidelines for CAH as formulated by The Endocrine Society Task Force.
title: A multidisciplinary analysis of the Belt and Road Initiative
Creators: name: Colombo, Natan
Publisher: name: Università Carlo Cattaneo - LIUC
Year: 2018

description: The paper sheds light on and critically analyses the Belt and Road Initiative, the most ambitious financial and  infrastructural  plan  China  is  promoting, inter  alia,  to  reinforce  its  geopolitical  role  in  the  new  global governance.  After  an  introductive  section on  the  evolution of  the  Chinese  economy  in  the  past decades, section 2 describes the background of the Initiative, with a focus on infrastructural connectivity, promotion of  industrialisation  in  the  involved  areas,and  collection  of  the  capitals  to  be allocated  for  its  projects. Section 3 deals with the main challenges and emerging problems, emphasising the geopolitical reactions of  China's  neighbouring  countries  to  the  Initiative,  the  delicate  issues  of  its  financial  sustainability  in  the long term, the connected macroeconomic policies, and the evolution path of the Renminbi toward a wider internationalisation,  in  addition  to  comments  on  the  infrastructural  development.  Several  conclusive remarks end the work
JISTIC: Identification of Significant Targets in Cancer
Creators: name: Pe'er, Dana
name: Mozes, Eyal
name: Sanchez-Garcia, Felix
name: Akavia, Uri David
Publisher: name: Columbia University
Year: 2010
Subjects: subject: Oncology
subject: Bioinformatics
subject: FOS: Computer and information sciences

description: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to the progressive conversion of normal human cells into malignant cancer cells. Interrogation of cancer genomes holds the promise of understanding this process, thus revolutionizing cancer research and treatment. As datasets measuring copy number aberrations in tumors accumulate, a major challenge has become to distinguish between those mutations that drive the cancer versus those passenger mutations that have no effect. We present JISTIC, a tool for analyzing datasets of genome-wide copy number variation to identify driver aberrations in cancer. JISTIC is an improvement over the widely used GISTIC algorithm. We compared the performance of JISTIC versus GISTIC on a dataset of glioblastoma copy number variation, JISTIC finds 173 significant regions, whereas GISTIC only finds 103 significant regions. Importantly, the additional regions detected by JISTIC are enriched for oncogenes and genes involved in cell-cycle and proliferation. JISTIC is an easy-to-install platform independent implementation of GISTIC that outperforms the original algorithm detecting more relevant candidate genes and regions. The software and documentation are freely available and can be found at: http://www.c2b2.columbia.edu/danapeerlab/html/software.html
Transverse Momentum Distributions in proton - proton Collisions at LHC Energies and Tsallis Thermodynamics
Creators: name: Azmi, M. D.
name: Cleymans, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A detailed study of the transverse momentum distributions of charged particles produced in proton - proton collisions at LHC energies is presented. This is done using a thermodynamically consistent form of the Tsallis distribution. All variables used are thermodynamical and in particular, the temperature $T$ follows from the standard thermodynamic definition as being the derivative of the energy with respect to the (Tsallis) entropy. The momentum distribution of the final state particles obtained describe the transverse momentum distributions very well. The values of the parameters are determined from measurements by the ALICE, ATLAS and CMS collaborations and are discussed in detail. In particular, the Tsallis parameter, $q$ is found with consistent values for all the transverse momentum distributions despite large differences in kinematic regions and shows a slight increase with beam energy, reaching a value of 1.15 at 7 TeV. It is concluded that the hadronic system created in high-energy p - p collisions can be seen as obeying Tsallis thermodynamics.
description: 15 pages 9 figures
title: Grasping De(centralized) Fi(nance) Through the Lens of Economic Theory
Creators: name: Chiu, Jonathan
name: Kahn, Charles M.
name: Koeppl, Thorsten V.
Publisher: name: Bank of Canada
Year: 2022

description: In this article, we use a simple stylized model of collateralized lending to analyze the value
proposition and limitations of decentralized finance (DeFi). DeFi uses a decentralized ledger to
run smart contracts that automatically enforce the terms of a lending contract and safeguard
the collateral. DeFi can lower the costs associated with intermediated lending and improve
financial inclusion. Limitations are the volatility of the crypto collateral and stablecoins used for
settlement, the possible incompleteness of smart contracts and the lack of a reliable oracle. A
proper infrastructure reducing such limitations could improve the value of DeFi.
description: Dans cet article, nous utilisons un modèle stylisé et simple de prêts garantis pour examiner la proposition de valeur et les lacunes de la finance décentralisée. La finance décentralisée repose sur la technologie du grand livre distribué pour exécuter des contrats intelligents qui appliquent, de façon automatique, les modalités des contrats de prêt et protègent les garanties. D’une part, elle peut réduire les coûts associés aux prêts intermédiés et accroître l’inclusion financière; d’autre part, elle comporte des lacunes, comme la volatilité des cryptoactifs offerts en garantie et des cryptomonnaies stables utilisées pour les règlements, la possibilité que les contrats intelligents soient incomplets et le manque de sources d’informations exogènes fiables. Une infrastructure adéquate visant à atténuer ces faiblesses pourrait améliorer l’attrait de la finance décentralisée.
Khurbn-geshtaltn bay H. Leivick
Creators: name: Roskies, David G.
Publisher: name: Columbia University
Year: 2015
Subjects: Holocaust, Jewish (1939-1945)
Jews

description: An analysis of H. Leivick's play, Di khasene in Fernvald, written soon after the playwright's historic visit to the D.P. camps in Germany.
Localization phase diagram of two-dimensional quantum percolation
Creators: name: Dillon, Brianna S.
name: Nakanishi, Hisao
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We examine quantum percolation on a square lattice with random dilution up to $q=38%$ and energy $0.001 \le E \le 1.6$ (measured in units of the hopping matrix element), using numerical calculations of the transmission coefficient at a much larger scale than previously. Our results confirm the previous finding that the two dimensional quantum percolation model exhibits localization-delocalization transitions, where the localized region splits into an exponentially localized region and a power-law localization region. We determine a fuller phase diagram confirming all three regions for energies as low as $E=0.1$, and the delocalized and exponentially localized regions for energies down to $E=0.001$. We also examine the scaling behavior of the residual transmission coefficient in the delocalized region, the power law exponent in the power-law localized region, and the localization length in the exponentially localized region. Our results suggest that the residual transmission at the delocalized to power-law localized phase boundary may be discontinuous, and that the localization length is likely not to diverge with a power-law at the exponentially localized to power-law localized phase boundary. However, further work is needed to definitively assess the characters of the two phase transitions as well as the nature of the intermediate power-law regime.
Fragment aus der Psalmübersetzung 21,19-22,3 (Baumburger Blatt); [1000-1099]
Creators: name: Notker Labeo
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2010

description: Entstehungsort: Unbekannt. - Entstehungszeit: 11. Jahrhundert
The Regulation of Leptin, Leptin Receptor and Pro-opiomelanocortin Expression by N-3 PUFAs in Diet-Induced Obese Mice Is Not Related to the Methylation of Their Promoters
Creators: name: Fan, Chaonan
name: Liu, Xinli
name: Shen, Wenwen
name: Deckelbaum, Richard Joseph
name: Qi, Kemin
Publisher: name: Columbia University
Year: 2011
Subjects: Nutrition

description: The expression of leptin is increased in obesity and inhibited by n-3 polyunsaturated fatty acids (n-3 PUFAs), but the underlying molecular mechanisms have not been firmly established. In this study, we investigated the effects of dietary n-3 PUFAs on the methylation of CpG islands in the promoter regions of the leptin, leptin-R and POMC genes, as well as the effects of n-3 PUFA status in early life on the modification of the promoters of these three genes. Male C57 BL/6J mice were fed a high-fat diet with one of four different fat types: sunflower oil (n-3 PUFA deficient), soy oil, fish oil, or a mixture of soy and fish oil (soy:fish oil = 1:1). Two low-fat diets with sunflower oil or soy oil served as controls. Female mice were fed two breeding diets, sunflower oil or a mixture of soy and fish oil (soy:fish oil = 1:1), during pregnancy and lactation to breed new pups. Compared to mice fed the control diets, the expression of leptin in fat tissue and leptin-R and POMC in the hypothalamus was higher in the diet-induced obesity (DIO) mice, and the n-3 PUFAs in the diets reversed these elevated expression levels. The mean methylation levels of CpG sites in the promoter regions of the leptin and POMC genes showed no difference between the DIO and the control diet groups nor between the n-3 PUFA-containing and -deficient diet groups. For the CpG sites in the promoter regions of leptin-R, no methylation was found in any of the DIO or control groups. Feeding mice with the n-3 PUFA diet during pregnancy and lactation did not affect CpG methylation in the leptin or POMC promoters. Our findings indicate that promoter DNA methylation may not be related to the expression of leptin, leptin-R or its related hypothalamic satiety regulator POMC.
Modulation of neutrophil NADPH oxidase activity by alpha-1 antitrypsin
Creators: name: Padraig Hawkins
Publisher: name: Royal College of Surgeons in Ireland
Year: 2020
Subjects: Medicine

description: Alpha-1 antitrypsin is a serine protease inhibitor that demonstrates an array of additional immunomodulatory functions. Individuals with the genetic condition, alpha-1 antitrypsin deficiency (AATD) are at increased risk of early onset emphysematous lung disease. This lung disease is partly driven by neutrophil mediated lung destruction in an environment of low AAT. The diverse functions of AAT appear to point to the pathogenesis of lung disease in AATD being more complex than a mere protease/anti-protease imbalance. There is growing evidence of the role of immune cell derived oxidative stress in the pathogenesis of non-genetic COPD. No such role has been firmly established in AATD related lung disease, while there is some evidence that AAT may affect immune cell O2- production, based on in vitro studies. The aim of this study was to examine the effects of AAT on neutrophil reactive oxygen species (ROS) production and to determine ROS production by circulating neutrophils in AATD individuals.
 We investigated the effects of AAT on circulating neutrophils that had been exposed to fMLP and IL-8 using a cytochrome c reduction assay. We found that physiological concentrations of AAT were capable of significantly modulating neutrophil O2- production. We confirmed that the effects of AAT were directly related to NADPH oxidase activity by measuring O2 consumption in these cells and by demonstrating the assembly of NADPH oxidase subunits at the neutrophil cell membrane. Further to this, we showed that circulating neutrophils from AATD individuals exhibit enhanced O2- production in response to soluble stimuli (fMLP). This enhanced activity did not affect the cytosolic pH of the neutrophil, despite our finding of a reduced abundance of HVCN1 in AATD neutrophils. The mechanism of enhanced responsiveness to fMLP by AATD neutrophils appears to be related to the ability of AAT to bind fMLP and prevent engagement with FPR1 on the cell membrane. AAT augmentation therapy was shown to reduce neutrophil O2- production. In summary, this study demonstrates that AAT can bind fMLP, preventing engagement with FPR1. This interaction prevents the assembly of NADPH oxidase at the cell membrane and therefore reduces ROS production. In AATD individuals this equates to a more robust ROS production in response to stimuli, an abnormality which is corrected by the administration of AAT augmentation therapy.
title: Metastatic melanoma diagnosed secondary to recurrent intussusception
Creators: name: Satei, Alexander M.
Publisher: name: EURORAD
Year: 2022
Subjects: subject: Abdominal imaging
subject: Abdomen
subject: Gastrointestinal tract
subject: Small bowel
subject: CT
subject: Cancer
subject: Metastases
subject: Clinical Cases

description: Clinical History: An 81-year-old male with a history of treated melanoma in 2018 presented with recurrent abdominal pain and vomiting for 3 months. The pain was located in his central abdomen with each episode lasting up to 15 minutes. Esophagogastroduodenoscopy performed 3 weeks prior to admission was unremarkable.

description: 81 years, male
Constraining dark boson decay using neutron stars
Creators: name: Husain, Wasif
name: Sengupta, Dipan
name: Thomas, A W
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Inspired by the well known anomaly in the life time of the neutron, we investigate its consequences inside neutron stars. We first assess the viability of the neutron decay hypothesis suggested by Fornal and Grinstein within neutrons tars, in terms of the equation of state and compatibility with observed properties. This is followed by an investigation of the constraint in formation on neutron star cooling can place on the decay rate of the dark boson into standard model particles, in the context of various BSM ideas.
description: Invited review article for a special edition on neutron decay lifetime anomalies for the journal
Concepts of Stability in Discrete Optimization Involving Generalized Addition Operations
Creators: name: Chistyakov, Vyacheslav V.
name: Pardalos, Panos M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 90C31 (Primary), 90C27, 90C26 (Secondary)

description: The paper addresses the tolerance approach to the sensitivity analysis of optimal solutions to the nonlinear optimization problem of the form $$\mbox{$\bigoplus\limits_{y\in S}C(y)\to\min$\quad over\quad $S\in\mathcal{S}$,}$$ where $\mathcal{S}$ is a collection of nonempty subsets of a finite set $X$ such that the union of $\mathcal{S}$ is $X$ and the intersection of $\mathcal{S}$ is empty, $C$ is a cost (or weight) function from $X$ into $\mathbb{R}^+=[0,\infty)$ or $(0,\infty)$, and $\oplus$ is a continuous, associative, commutative, nondecreasing and unbounded binary operation of generalized addition on $\mathbb{R}^+$, called an A-operation. We evaluate and present sharp estimates for upper and lower bounds of costs of elements from $X$, for which an optimal solution to the above problem remains stable. These bounds present new results in the sensitivity analysis as well as extend most known results in a unified way. We define an invariant of the optimization problem---the tolerance function, which is independent of optimal solutions, and establish its basic properties, among which we mention a characterization of the set of all optimal solutions, the uniqueness of optimal solutions and extremal values of the tolerance function on an optimal solution.
description: 34 pages, 2 tables, LaTeX
Transform to Open Science Mission May 2022 Community Panel
Creators: name: Gentemann, Chelle L.
name: Ivey, Yvonne
name: Hall, Cynthia
name: Mastracchio, Karla
name: Luna-Cruz, Yaitza
name: Steponaitis, Elena
name: Murphy, Kevin
name: Baynes, Kathleen
name: Crawford, Steve
name: Truong, Amy
name: Reyes, Christian
name: Ward, Kevin
name: Cassidy, Emily
name: Martinez, Isabella
name: Stall, Shelley
name: Erdmann, Christopher
name: Lyon, Laura
Publisher: name: Zenodo
Year: 2022
Subjects: Open Science; Open Knowledge; Open-source

description: NASA’s Transform to Open Science (TOPS) mission is being designed to support the adoption of open science and broaden participation in science. During the 2023 Year of Open Science TOPS is planning a broad suite of resources, events, and activities. This is the first meeting of the TOPS Community Panel which reviews and provides input on NASA’s strategy for transitioning to open-source science and plans for the Year of Open Science in 2023. This panel meeting will bring together leaders from the open science, open source software, and data science communities with the NASA TOPS team for a detailed review of TOPS plans.
Minorities and Storable Votes
Creators: name: Casella, Alessandra M.
name: Palfrey, Thomas R.
name: Riezman, Raymond
Publisher: name: Columbia University
Year: 2008
Subjects: subject: Political science
subject: FOS: Political science

description: The paper studies a simple voting system that can increase the power of minorities
without sacrificing aggregate efficiency or treating voters asymmetrically. Storable
votes grant each voter a stock of votes to spend as desired over a series of binary
decisions and thus elicit voters’ strength of preferences. The potential of the mechanism
is particularly clear in the presence of systematic minorities: by accumulating
votes on issues that it deems most important, the minority can win occasionally.
But because the majority typically can outvote it, the minority wins only if its
strength of preference is high and the majority’s strength of preference is low. The
result is that the minority’s preferences are represented, while aggregate efficiency
either falls little or in fact rises, relative to simple majority voting. The theoretical
predictions of our model are confirmed by a series of experiments: the frequency
of minority victories, the relative payoff of the minority versus the majority, and
the aggregate payoffs all match the theory.
Innovation in context: Cosmotechnics in the Anthropocene
Creators: name: Hinder, Ben
Publisher: name: Zenodo
Year: 2022
Subjects: Cosmotechnics
Anthropocene
Technology
Innovation
Transformation

description: Climate change, and environmental crises broadly, are not a threat to be avoided but constitute an unprecedented and permanent shift of the global system which social systems must adapt to (Campbell, McHugh and Ennis, 2018; Wakefield, 2018; IPCC, 2022). This is the abstract of Ben Hinder's presentation to the New crtical geographies of enviro-tech innovation group at the Royal Geographic Socieity's conference in 2022.
D1.2 Data Management Plan
Creators: name: Daquino, Marilena
name: Peroni, Silvio
name: Asprino, Luigi
Publisher: name: Zenodo
Year: 2022
Subjects: DMP
SPICE
H2020

description: This deliverable introduces the Data Management Plan (DMP) of SPICE. The DMP outlines the strategy for the management and accessibility of data generated in the project, including software and data from experiments, surveys, and interviews.
Greater lean tissue and skeletal muscle mass are associated with higher bone mineral content in children
Creators: name: Dorsey, Karen
name: Thornton, John
name: Heymsfield, Steven B.
name: Gallagher, Dympna
Publisher: name: Columbia University
Year: 2010
Subjects: Nutrition
Medicine

description: To compare the relationship of skeletal muscle mass with bone mineral content in an ethnically diverse group of 6 to 18 year old boys and girls. 175 healthy children (103 boys; 72 girls) had assessments of body mass, height, and Tanner stage. Whole body bone mineral content, non-bone lean body mass (nbLBM), skeletal muscle mass, and fat mass were assessed using dual-energy X-ray absorptiometry (DXA). Muscle mass was estimated from an equation using appendicular lean soft tissue measured by DXA, weight and height. Estimates of skeletal muscle mass and adipose tissue were also assessed by whole body multi-slice magnetic resonance imaging (MRI). Linear regression was used to determine whether skeletal muscle mass assessed by DXA or by MRI were better predictors of bone mineral content compared with nbLBM after adjusting for sex, age, race or ethnicity, and Tanner stage. Greater skeletal muscle mass was associated with greater bone mineral content (p *#60; 0.001). The skeletal muscle mass assessed by MRI provided a better fitting regression model (determined by R2 statistic) compared with assessment by DXA for predicting bone mineral content. The proportion of skeletal muscle mass in nbLBM was significantly associated with greater bone mineral content adjusted for total nbLBM. This study is among the first to describe and compare the relationship of skeletal muscle to bone using both MRI and DXA estimates. The results demonstrate that the use of MRI provides a modestly better fitting model for the relationship of skeletal muscle to bone compared with DXA. Skeletal muscle had an impact on bone mineral content independent of total non-bone lean body mass. In addition, Hispanics had greater bone mineral content compared to other race and ethnic groups after adjusting for sex, age, adipose tissue, skeletal muscle mass, and height.
VGS31b: a highly inclined ring along a filament in a void. Implication for the cold accretion
Creators: name: Spavone, M.
name: Iodice, E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: VGS31b is a highly-inclined ring galaxy found along a filament in a void (Kreckel et al. 2012). Detailed photometry, by using u, g, r, i, z SDSS images, has shown that the overall morphology of VGS31b is very tricky, due to (i) the presence of a highly inclined (72 deg) ring-like structure, which reaches the galaxy center tracing a "spiral-like" pattern, (ii) a one sided tail towards North-East and (iii) a bar in the central regions (Beygu et al. 2013). Such structure is reasonably the result of a "second event" in the evolution history of this galaxy, which could be a gravitational interaction with a companion galaxy or with the environment. The main aim of the present work is to address the most reliable formation scenario for this object, by comparing the observed properties, i.e. structure, baryonic mass, kinematics and chemical abundances, with the theoretical predictions. In particular, we have used archival spectroscopic data, to derive the metallicity in the ring: we found a very low, sub-solar average value of Z = 0.3 Zsun, comparable with other polar ring/disk galaxies, but lower than those measured for ordinary spirals of similar luminosity. The study of the chemical abundances in polar ring/disk galaxies and related objects has received an increasing attention in recent years, since it has revealed to be a key-parameter to disentangle among the formation scenarios suggested for this class of objects: major merging, tidal accretion or cold accretion. In the present work we check the cold accretion of gas through a "cosmic filament" as a possible scenario for the formation of the ring-like structure in VGS31b.
description: 15 pages, 12 figures. Accepted for publication in MNRAS. Figure 2 changed. arXiv admin note: text overlap with arXiv:1104.2052
Environmental Data Initiative One-Pager
Creators: name: Vanderbilt, Kristin
name: Gries, Corinna
name: Smith, Colin
name: O'brien, Margaret
name: Grossman-Clarke, Susanne
name: Servilla, Mark
Publisher: name: ESIP
Year: 2020
Subjects: subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: This item is a one-pager introducing the services offered by the Environmental Data Initiative.
Longitudinal molecular microbial analysis of influenza-like illness in New York City, may 2009 through may 2010
Creators: name: Tokarz, Rafal
name: Kapoor, Vishal
name: Wu, Winfred
name: Lurio, Joseph
name: Jain, Komal
name: Mostashari, Farzad
name: Briese, Thomas
name: Lipkin, W. Ian
Publisher: name: Columbia University
Year: 2011
Subjects: Communicable diseases
Epidemiology
Public health

description: We performed a longitudinal study of viral etiology in samples collected in New York City during May 2009 to May 2010 from outpatients with fever or respiratory disease symptoms in the context of a pilot respiratory virus surveillance system. Samples were assessed for the presence of 13 viruses, including influenza A virus, by MassTag PCR. At least one virus was detected in 52% of 940 samples analyzed, with 3% showing co-infections. The most frequently detected agents were rhinoviruses and influenza A, all representing the 2009 pandemic H1N1 strain. The incidence of influenza H1N1-positive samples was highest in late spring 2009, followed by a decline in summer and early fall, when rhinovirus infections became predominant before H1N1 reemerged in winter. Our study also identified a focal outbreak of enterovirus 68 in the early fall of 2009. MassTag multiplex PCR affords opportunities to track the epidemiology of infectious diseases and may guide clinicians and public health practitioners in influenza-like illness and outbreak management. Nonetheless, a substantial proportion of influenza-like illness remains unexplained underscoring the need for additional platforms.
D1.2 Data Management Plan
Creators: name: Daquino, Marilena
name: Peroni, Silvio
Publisher: name: Zenodo
Year: 2020
Subjects: DMP
SPICE
H2020

description: This deliverable introduces the Data Management Plan (DMP) of SPICE. The DMP outlines the strategy for the management and accessibility of data generated in the project, including software and data from experiments, surveys and interviews.
Pion and Kaon Structure Functions at the EIC
Creators: name: Horn, Tanja
name: Roberts, Craig D.
Publisher: name: Zenodo
Year: 2020

description: We provide a summary of discussions at the week-long tele-workshop “Pion and Kaon Structure
 Functions at the EIC”, held in June 2020 under the auspices of the Center for Frontiers in Nuclear
 Science. The presentations and attendant conversations provided a perspective on existing
 challenges and future opportunities as experiment, phenomenology, and theory reach toward
 the goals of revealing the origin and consequences of emergent hadronic mass using modern and
 planned facilities. The potential for discovery at modern and planned facilities was highlighted,
 with emphasis on the electron ion collider.
Exit probability in inflow dynamics: nonuniversality induced by range, asymmetry and fluctuation
Creators: name: Roy, Parna
name: Biswas, Soham
name: Sen, Parongama
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Probing deeper into the existing issues regarding the exit probability (EP) in one dimensional dynamical models, we consider several models where the states are represented by Ising spins and the information flows inwards. At zero temperature, these systems evolve to either of two absorbing states. The exit probability $E(x)$, which is the probability that the system ends up with all spins up starting with $x$ fraction of up spins is found to have the general form $E(x) = x^α/\left[x^α+ (1-x)^α\right]$. The exit probability exponent $α$ strongly depends on $r$, the range of interaction, the symmetry of the model and the induced fluctuation. Even in a nearest neighbour model, nonlinear form of EP can be obtained by controlling the fluctuations and for the same range, different models give different results for $α$. Non-universal behaviour of the exit probability is thus clearly established and the results are compared to existing studies in models with outflow dynamics to distinguish the two dynamical scenarios.
description: 5 pages, 6 figures
Philobiblon; 1473
Creators: name: Richardus De Bury
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2013

description: Bibliogr. Nachweis: Hain/Copinger 4151. VK 1021. Pell-Pol 3101. BNCI R 122. Pol 3351. BMC I, 232 (IA. 3708). Goff R191. IBP 4765
Appendices A-F from Personality-specific carry-over effects on breeding
Creators: name: Harris, Stephanie M.
name: Descamps, Sébastien
name: Sneddon, Lynne U.
name: Cairo, Milena
name: Bertrand, Philip
name: Patrick, Samantha C.
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Carry-over effects describe the phenomenon whereby an animal's previous conditions influence its subsequent performance. Carry-over effects are unlikely to affect individuals uniformly, but the factors modulating their strength are poorly known. Variation in the strength of carry-over effects may reflect individual differences in pace-of-life: slow-paced, shyly behaved individuals are thought to favour an allocation to self-maintenance over current reproduction, compared to their fast-paced, boldly behaved conspecifics (the pace-of-life syndrome hypothesis). Therefore, detectable carry-over effects on breeding should be weaker in bolder individuals, as they should maintain an allocation to reproduction irrespective of previous conditions, while shy individuals should experience stronger carry-over effects. We tested this prediction in black-legged kittiwakes breeding in Svalbard. Using miniature biologging devices, we measured non-breeding activity of kittiwakes and monitored their subsequent breeding performance. We report a number of negative carry-over effects of non-breeding activity on breeding, which were generally stronger in shyer individuals: more active winters were followed by later breeding phenology and poorer breeding performance in shy birds, but these effects were weaker or undetected in bolder individuals. Our study quantifies individual variability in the strength of carry-over effects on breeding and provides a mechanism explaining widespread differences in individual reproductive success.
Maximization of the olfactory receptor neuron selectivity in the sub-threshold regime
Creators: name: Vidybida, Alexander
Publisher: name: arXiv
Year: 2023
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: It is known that if odors are presented to an olfactory receptor neuron (ORN) in a sub-threshold concentration -- i.e., when the average value of the number of the ORN bound receptor proteins (RPs) is insufficient for the generation of spikes, but such a generation is still possible due to fluctuations around the average value -- the ORN selectivity can be higher than the selectivity at higher concentrations and, in particular, higher than the selectivity of the ORN's RPs. In this work, the optimal odorant concentration providing the highest ORN selectivity is found in the framework of a simplified ORN model, and the dependence of the highest selectivity on the total number of RPs in the ORN, $N$, and its threshold value $N_{0}$ is derived. The effect of enhanced selectivity in the sub-threshold regime is best manifested, if $N_{0}$ is close to either unity or $N$. It is also more pronounced at large $N$-values.
description: 13 pages, 4 figures, 29 references