cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
sj-docx-10-tct-10.1177_15330338231183585 - Supplemental material for Prognostic Significance of Advanced Age in Patients with T1a Renal Cell Carcinoma Treated by Microwave Ablation: A 16-Year Experience
Creators: name: Hou, Qidi
name: Wang, Yaxi
name: Zhang, Dongyun
name: Luo, Yanchun
name: Dong, Linan
name: Mu, Mengjuan
name: Yu, Jie
name: Liang, Ping
Publisher: name: SAGE Journals
Year: 2023
Subjects: Oncology and Carcinogenesis not elsewhere classified
Radiology and Organ Imaging
Biochemistry

description: Supplemental material, sj-docx-10-tct-10.1177_15330338231183585 for Prognostic Significance of Advanced Age in Patients with T1a Renal Cell Carcinoma Treated by Microwave Ablation: A 16-Year Experience by Qidi Hou, Yaxi Wang, Dongyun Zhang, Yanchun Luo, Linan Dong, Mengjuan Mu, Jie Yu and Ping Liang in Technology in Cancer Research & Treatment
Labor provisions in bilateral investment treaties: Does the new US Model BIT provide a template for the future?
Creators: Prislan, Vid
Zandvliet, Ruben
Publisher: name: Columbia University
Year: 2013
Subjects: Finance
International relations

description: Unlike its trade-counterpart, the relationship between international investment law and labor standards has neither resulted in much treaty practice nor attracted extensive scholarly attention. The 2004 US Model bilateral investment treaty (BIT) was among the first to devote a full article to labor standards (Article 13). The revised US Model BIT, published in May 2012, updates and expands this provision.
Macrophages producing chondroitin sulfate proteoglycan‐4 induce neuro‐cardiac junction impairment in Duchenne muscular dystrophy
Creators: name: Crosti, Maria Cristina
name: Calogero, Antonella
name: Rizzi, Roberto
name: Brambilla, Francesca
name: Di Silvestre, Dario
name: De Falco, Elena
name: Zigiotto, Rebecca
name: Parisi, Chiara
name: Lanzuolo, Chiara
name: Bombaci, Mauro
name: Maiullari, Fabio
name: Bearzi, Claudia
name: Fratini, Nicole
name: Landoni, Elisa
name: Milan, Marika
name: Seliktar, Dror
name: De Paolis, Veronica
name: Cordiglieri, Chiara
name: Maiullari, Silvia
name: Ceraolo, Maria Grazia
name: Dotti, Gianpietro
name: Torrente, Yvan
name: Mauri, Pierluigi
name: Chirivì, Maila
name: Soluri, Andrea
name: Toccafondi, Mirco
Publisher: name: Wiley
Year: 2024

description:
Duchenne muscular dystrophy (DMD) is caused by the absence of the full form of the dystrophin protein, which is essential for maintaining the structural integrity of muscle cells, including those in the heart and respiratory system. Despite progress in understanding the molecular mechanisms associated with DMD, myocardial insufficiency persists as the primary cause of mortality, and existing therapeutic strategies remain limited. This study investigates the hypothesis that a dysregulation of the biological communication between infiltrating macrophages (MPs) and neurocardiac junctions exists in dystrophic cardiac tissue. In a mouse model of DMD (mdx), this phenomenon is influenced by the over-release of chondroitin sulfate proteoglycan-4 (CSPG4), a key inhibitor of nerve sprouting and a modulator of the neural function, by MPs infiltrating the cardiac tissue and associated with dilated cardiomyopathy, a hallmark of DMD. Givinostat, the histone deacetylase inhibitor under current development as a clinical treatment for DMD, is effective at both restoring a physiological microenvironment at the neuro-cardiac junction and cardiac function in mdx mice in addition to a reduction in cardiac fibrosis, MP-mediated inflammation, and tissue CSPG4 content. This study provides novel insight into the pathophysiology of DMD in the heart, identifying potential new biological targets.
Additional file 8 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 8: eTable 6. Association of changes in frailty status with cardiovascular death and all-cause mortality, further controlling for frailty status at wave 2014.
sj-docx-1-chl-10.1177_17475198231212673 – Supplemental material for Expected and unexpected products from reacting Sanger’s reagent with p-phenylenediamine
Creators: name: Plater, Michael John
name: Harrison, William TA
Publisher: name: SAGE Journals
Year: 2023
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material, sj-docx-1-chl-10.1177_17475198231212673 for Expected and unexpected products from reacting Sanger’s reagent with p-phenylenediamine by Michael John Plater and William TA Harrison in Journal of Chemical Research
title: Zwischen sozialer Sicherung und freiem Fall
Creators: name: Schüttbacher, Gabriele Helene
Year: 2008

description: Der Sozialstaat hatte seit dem Ende des 2. Weltkrieges ein bis dahin nie gekanntes Ausmaß an sozialer Sicherheit und Teilhabe für die breite Masse der Bevölkerung ermöglicht, seit Beginn der 1980er Jahre bahnte sich jedoch das Ende des „Goldenen Zeitalters“ des Wohlfahrtsstaates an. Niedrigere Wachstumsraten der Wirtschaft, steigende Erwerbslosigkeit, Veränderung der Altersstruktur der Gesellschaft und die Auflösung traditioneller Familienstrukturen brachen die Normalitätsannahmen, auf denen der Sozialstaat aufbaute, zum Wanken. Mit dem Ende des Ausbaus wurde auch evident, dass das an sich gut ausgebaute System der sozialen Sicherung keineswegs Verarmungsrisiken ausschließt. Die Verbreitung von Beschäftigungsverhältnissen abseits des (männlichen) Normalarbeitsverhältnisses – wie Teilzeitarbeit, Leiharbeit, geringfügige Beschäftigung etc. nimmt kontinuierlich zu. Vor allem für Frauen wird atypische Beschäftigung zunehmend typisch. Veränderungen in Richtung Atypisierung am Arbeitsmarkt betreffen die sozialen Sicherungssysteme insgesamt, wenn die Frage nach den Modi für dessen Um- oder Rückbau und seine Finanzierung gestellt werden muss. Sie stellen ebenso die Frage nach der Zukunft der Arbeit und damit auch die nach ihrer Funktion für den Staat und den/die EinzelneN in der Vergangenheit und in Zukunft. Politische Handlungsoptionen wurden von den zentralen Akteuren in unterschiedlicher Weise genützt – von Bestrebungen, bestimmte Beschäftigungsformen zu verbieten bis hin zu politischer Non-Decision.
Genome-wide copy number variation association study in anorexia nervosa
Creators: name: Birgegård, Andreas
name: Strober, Michael
name: Kaplan, Allan S.
name: Yilmaz, Zeynep
name: Lin, Tian
name: Watson, Hunna J.
name: McRae, Allan
name: Szatkiewicz, Jin P.
name: Thornton, Laura M.
name: Savva, Androula
name: Jordan, Jennifer
name: Pedersen, Nancy L.
name: Brandt, Harry
name: Kennedy, Martin A.
name: Halmi, Katherine A.
name: Davies, Helena L.
name: Mitchell, James
name: Berrettini, Wade H.
name: Baker, Jessica H.
name: Bulik, Cynthia M.
name: Borg, Stina
name: Kirov, George
name: Munn-Chernoff, Melissa A.
name: Landén, Mikael
name: Karlsson, Robert
name: Woodside, D. Blake
name: Wen, Jia
name: Chawner, Samuel J. R. A.
name: Leppä, Virpi M.
name: Crawford, Steven
name: Gordon, Scott
name: Song, Jie
name: Wray, Naomi R.
name: Kaye, Walter H.
name: Walker, Alicia
name: Parker, Richard
name: Martin, Nicholas G.
name: Sullivan, Patrick F.
name: Sidorenko, Julia
name: Fundín, Bengt T.
Publisher: name: Springer Nature
Year: 2024

description:
This study represents the first large-scale investigation of rare (<1% population frequency) copy number variants (CNVs) in anorexia nervosa (AN). Large, rare CNVs are reported to be causally associated with anthropometric traits, neurodevelopmental disorders, and schizophrenia, yet their role in the genetic basis of AN is unclear. Using genome-wide association study (GWAS) array data from the Anorexia Nervosa Genetics Initiative (ANGI), which included 7414 AN case and 5044 controls, we investigated the association of 67 well-established syndromic CNVs and 178 pleiotropic disease-risk dosage-sensitive CNVs with AN. To identify novel CNV regions (CNVRs) that increase the risk of AN, we conducted genome-wide association studies with a focus on rare CNV-breakpoints (CNV-GWAS). We found no net enrichment of rare CNVs, either deletions or duplications, in AN, and none of the well-established syndromic or pleiotropic CNVs had a significant association with AN status. However, the CNV-GWAS found 21 nominally associated CNVRs that contribute to AN risk, covering protein-coding genes implicated in synaptic function, metabolic/mitochondrial factors, and lipid characteristics, like the CD36 (7q21.11) gene, which transports long-chain fatty acids into cells. CNVRs intersecting genes previously related to neurodevelopmental traits include deletions of NRXN1 intron 5 (2p16.3), IMMP2L (7q31.1), and PTPRD (9p23). Overall, given that our study is well powered to detect the CNV burden level reported for schizophrenia, we can conclude that rare CNVs have a limited role in the etiology of AN, as reported for bipolar disorder. Our nominal associations for the 21 discovered CNVRs are consistent with AN being a metabo-psychiatric trait, as demonstrated by the common genetic architecture of AN, and we provide association results to allow for replication in future research.
After Equality: Why a Decreasing Turnout Harms Democracy (Reviewed: Armin Schäfer: Der Verlust politischer Gleichheit)
Creators: name: Fock, Anne
Publisher: name: Intergenerational Justice Review
Year: 2016

description: No abstract
description: Intergenerational Justice Review, Vol 8, No 1 (2016): Low Electoral Turnout among Young Voters
Complex adaptive systems science in the era of global sustainability crisis
Creators: name: Zhang, Qi
name: Wang, Zhangyang
name: Huang, Ruihong
name: An, Li
name: Grimm, Volker
name: Turner, B.L.
name: Liu, Jianguo
Publisher: name: Elsevier
Year: 2024

description:
A significant number and range of challenges besetting sustainability can be traced to the actions and interactions of multiple autonomous agents (people mostly) and the entities they create (e.g., institutions, policies, social network) in the corresponding social-environmental systems (SES). To address these challenges, we need to understand decisions made and actions taken by agents, the outcomes of their actions, including the feedbacks on the corresponding agents and environment. The science of complex adaptive systems—CAS science—has a significant potential to handle such challenges. We address the advantages of CAS science for sustainability by identifying the key elements and challenges in sustainability science, the generic features of CAS, and the key advances and challenges in modeling CAS. Artificial intelligence and data science combined with agent-based modeling promise to improve understanding of agents’ behaviors, detect SES structures, and formulate SES mechanisms.
sj-docx-1-han-10.1177_15589447231211602 – Supplemental material for Arthroscopic-Assisted Treatment of Bennett Fractures: A Potentially Advantageous Operative Procedure?
Creators: name: Torres Fuentes, Carlos Eduardo
name: Meneses Argalle, Julian David
name: Romero León, Carol Andrea
Publisher: name: SAGE Journals
Year: 2023
Subjects: Medicine
Orthopaedics
Sports Medicine

description: Supplemental material, sj-docx-1-han-10.1177_15589447231211602 for Arthroscopic-Assisted Treatment of Bennett Fractures: A Potentially Advantageous Operative Procedure? by Carlos Eduardo Torres Fuentes, Julian David Meneses Argalle and Carol Andrea Romero León in HAND
Additional file 9 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 9: eTable 7. Association of changes in frailty status with cardiovascular death and all-cause mortality, in considering the losses censored at the median time of follow-up (3.88 years).
Supplemental Material - Transcranial Motor Evoked Potentials as a Predictive Modality for Postoperative Deficit in Cervical Spine Decompression Surgery – A Systematic Review and Meta-Analysis
Creators: name: Reddy, Rajiv P.
name: Singh-Varma, Anya
name: Chang, Robert
name: Vedire, Abhinav
name: Anetakis, Katherine M.
name: Balzer, Jeffrey R.
name: Crammond, Donald J.
name: Shandal, Varun
name: Lee, Joon Y.
name: Shaw, Jeremy D.
name: Thirumala, Parthasarathy D.
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Orthopaedics
subject: Sports Medicine
subject: Surgery

description: Supplemental Material for Transcranial Motor Evoked Potentials as a Predictive Modality for Postoperative Deficit in Cervical Spine Decompression Surgery – A Systematic Review and Meta-Analysis by Rajiv P. Reddy, Anya Singh-Varma, Robert Chang, Abhinav Vedire, Katherine M. Anetakis, Jeffrey R. Balzer, Donald J. Crammond, Varun Shandal, Joon Y. Lee, Jeremy D. Shaw, and Parthasarathy D. Thirumala in Global Spine Journal
title: Factors Impacting Behavioral Intention to Use Online Learning of Junior College Students in a Private Vocational University in Chengdu, China
Creators: name: Yangbaixue, Zhong
Publisher: name: Assumption University Press
publisherIdentifierScheme: ROR
Year: 2025
Subjects: E-Learning Quality
Perceived Usefulness
Perceived Ease of Use
Behavioral Intention

description: The Scholar: Human Sciences, 17, 1, 53-65
Bone loss with aging is independent of gut microbiome in mice
Creators: name: Yan, Jing
name: Sartor, R. Balfour
name: Hammamieh, Rasha
name: You, Xiaomeng
name: Chakraborty, Nabarun
name: Kacena, Melissa A.
name: Charles, Julia F.
name: Nobakhti, Sabah
name: Hoke, Allison
name: Campbell, Ross
name: Herzog, Jeremy
name: Shefelbine, Sandra
Publisher: name: Springer Nature
Year: 2024

description:
Emerging evidence suggests a significant role of gut microbiome in bone health. Aging is well recognized as a crucial factor influencing the gut microbiome. In this study, we investigated whether age-dependent microbial change contributes to age-related bone loss in CB6F1 mice. The bone phenotype of 24-month-old germ-free (GF) mice was indistinguishable compared to their littermates colonized by fecal transplant at 1-month-old. Moreover, bone loss from 3 to 24-month-old was comparable between GF and specific pathogen-free (SPF) mice. Thus, GF mice were not protected from age-related bone loss. 16S rRNA gene sequencing of fecal samples from 3-month and 24-month-old SPF males indicated an age-dependent microbial shift with an alteration in energy and nutrient metabolism potential. An integrative analysis of 16S predicted metagenome function and LC-MS fecal metabolome revealed an enrichment of protein and amino acid biosynthesis pathways in aged mice. Microbial S-adenosyl methionine metabolism was increased in the aged mice, which has previously been associated with the host aging process. Collectively, aging caused microbial taxonomic and functional alteration in mice. To demonstrate the functional importance of young and old microbiome to bone, we colonized GF mice with fecal microbiome from 3-month or 24-month-old SPF donor mice for 1 and 8 months. The effect of microbial colonization on bone phenotypes was independent of the microbiome donors’ age. In conclusion, our study indicates age-related bone loss occurs independent of gut microbiome.
sj-docx-1-isp-10.1177_00207640231212091 – Supplemental material for Decomposition analysis of the difference in depressive symptoms between urban and rural employed people in China: Unpaid work plays an important role
Creators: name: Jiang, Qinqin
name: Zhao, Zhe
name: Liu, Yijun
name: Wei, Zhenbang
name: Bing, Yan
name: Zhang, Feng
name: Liu, Jiahao
name: Gao, Lei
name: Sun, Jinhai
name: Yuan, Lei
Publisher: name: SAGE Journals
Year: 2023
Subjects: Psychology not elsewhere classified
Psychiatry (incl. Psychotherapy)

description: Supplemental material, sj-docx-1-isp-10.1177_00207640231212091 for Decomposition analysis of the difference in depressive symptoms between urban and rural employed people in China: Unpaid work plays an important role by Qinqin Jiang, Zhe Zhao, Yijun Liu, Zhenbang Wei, Yan Bing, Feng Zhang, Jiahao Liu, Lei Gao, Jinhai Sun and Lei Yuan in International Journal of Social Psychiatry
title: Der Iran seit 1979 bis 2008 und seine Beziehungen zu Österreich
Creators: name: Piran-Naderi, Azita
Year: 2008

description: Wie sahen die Beziehungen zwischen Österreich und Iran in den letzen 30 Jahren aus? Dies war die Leitfrage dieser Arbeit. Ausgehend davon wird ein kurzer Rückblick gegeben, wie lange die Beziehungen zurück gehen und wie sich die bilaterale Zusammenarbeit in den verschiedensten Bereichen, wie Wirtschaft, Politik und Kultur entwickelt haben. Ein besonderes Augenmerk wird auf die inneriranischen Prozesse gerichtet, um die jeweils geltenden Rahmenbedingungen für die Außenbeziehungen zu erörtern. Der Iran-Irakkrieg, das illegale Waffengeschäft Noricum, der Mordfall Ghassemlou, die Wiederaufbau Arbeiten nach dem Krieg, die Öffnung und Liberalisierung des Iran unter dem Hoffnungsträger Khatami, der Besuch der Nobelpreisträgerin Shirin Ebadi in Wien bis hin zur Kehrtwende in Irans Außenpolitik unter Präsident Ahmadinejad, sowie ein kurzer Einblick in den Atomkonflikt und der Bau der umstrittenen Nabucco Pipeline geben eine detaillierte Übersicht über die Geschehnisse seit der Islamischen Revolution 1979 und verdeutlichen, dass die Beziehungen zwischen diesen beiden Ländern immer als sehr gut und freundschaftlich bezeichnet werden können, obgleich auch viele Stolpersteine zu gröberen Krisen hätten führen können.
description: What kind of relations were the existing relations between Austria and Iran in the past 30 years? This was the central question in this thesis. Based on this a short review is given of how long these relations have existed and how the bilateral cooperation in the diverse fields like economy, politics and culture have emerged. A special focus is set on the domestic processes in order to reason the basic conditions which determine Iran’s external relations. The Iran-Iraq-war, the illegal weapons deal Noricum, the homicide case of Ghassemlou, the era of reconstruction, the creation of political awareness and liberalization under president Khatami, Shirin Ebadi’s award of the Nobel peace price and her visit to Vienna, up to the turnabout in Iran’s foreign policy under president Ahmadinejad, as well as a short insight on the conflict of nuclear energy and the construction of the controversial Nabucco pipeline will present a detailed overview on the incidents since the Islamic Revolution 1979 and point out that the ties between these two countries have always been very good and cordially, also bearing in mind that some obstacles could have lead to broader crises.
Pathologic dural invasion is associated with regional recurrence in olfactory neuroblastoma: A multi‐institutional study
Creators: name: Hwang, Peter H.
name: Nayak, Jayakar V.
name: Patel, Chirag
name: Patel, Zara M.
name: Zenonos, Georgios A.
name: Van Gompel, Jamie J.
name: Choby, Garret
name: Wang, Eric W.
name: Tang, Anthony
name: Geltzeiler, Mathew
name: Gardner, Paul
name: Sanusi, Olabisi
name: Snyderman, Carl
name: Thorp, Brian D.
name: Fung, Nicholas
name: Almeida, Joao Paulo
name: Champagne, Pierre‐Olivier
name: Fernandez‐Miranda, Juan C.
name: Pinheiro‐Neto, Carlos
name: Celda, Maria Peris
name: Zwagerman, Nathan T.
name: Taori, Suchet
Publisher: name: Wiley
Year: 2024

description:
OBJECTIVE: Neck metastases are a poor prognostic factor in olfactory neuroblastoma (ONB). Pathologic dural invasion (pathDI) may increase the risk of neck metastases due to invasion of dural lymphatics. We aim to evaluate the prognostic value of pathDI in predicting rates of neck metastases and recurrence using a large, multicenter database of ONB patients. DATA SOURCES: Retrospective review of a prospective, multicenter database of electronic health records of all patients who presented with ONB between 2005 and 2021 at nine tertiary academic care centers within North America. REVIEW METHODS: Clinicopathologic features including modified Kadish staging systems, margin status, treatment modalities, Hyams grading, follow-up time, and survival. RESULTS: Of 258 ONB patients, 189 patients met the inclusion criteria. The 10-year neck recurrence-free survival (neck-RFS) rates were 85.7% (75.6‒97.3) and 61.8% (47.9‒79.8) for patients without and with pathDI, respectively (p = 0.018). Time-to-event multivariable regression analysis found pathDI to have an odds ratios of 9.7 (95% confidence interval [CI] 1.2-80.4, p = 0.04) for neck-RFS and 9.5 for RFS at any site (95% CI 1.1-83.3, p = 0.04). CONCLUSION: In multivariable analysis, the presence of pathDI appears to be the strongest predictor of neck recurrence and recurrence at any site. Future studies exploring the benefit of elective neck dissection or radiation for patients with pathDI may impact disease management.
Additional file 10 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 10: eTable 8. Association of changes in frailty status with cardiovascular death and all-cause mortality, in considering the losses censored at the end of follow-up (5.24 years).
title: Factors Impacting Intention to Use and Satisfaction with Blended Learning of Students in Business English Major in Guangdong, China
Creators: name: Yingzhi Fang
Publisher: name: Assumption University Press
publisherIdentifierScheme: ROR
Year: 2025
Subjects: Satisfaction
System Quality
Information Quality
Social Identity
Intention to Use

description: The Scholar: Human Sciences, 17, 1, 66-77
Les  Échos de Russie : bulletin de la délégation du Parti socialdémocrate et du Parti socialiste-révolutionnaire
Creators: name: Partija socialistov-revoljucionerov
Publisher: name: Le Progrès
Year: 1900
Subjects: Revolutionär
Sozialdemokratie

description: publié sous la direction de Paul Axelrod ... [et al.]
description: 1918, N 1(1 Jan.)-
Additional file 11 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 11: eTable 9. Association of changes in frailty status with cardiovascular death and all-cause mortality, after excluding deaths within the first year.
Trajectories of attention problems in preschoolers born very preterm
Creators: name: Pastyrnak, Steven L.
name: Hofheimer, Julie A.
name: McGowan, Elisabeth C.
name: Neal, Charles R.
name: Camerota, Marie
name: Marsit, Carmen J.
name: O'Shea, Thomas Michael
name: Carter, Brian S.
name: Helderman, Jennifer
name: Castellanos, Francisco Xavier
name: Lester, Barry M.
name: Check, Jennifer
name: Smith, Lynne M.
Publisher: name: Wiley
Year: 2024

description:
BACKGROUND: Children born preterm are at heightened risk for neurodevelopmental impairment, including specific deficits in attention. Few studies have investigated change over time in attention problems prior to school entry. The current study aims to describe trajectories of attention problems from age 2 through 5 years in a cohort of children born <30 weeks of gestational age (GA), identify sociodemographic, medical, and neurobehavioral characteristics associated with attention trajectories, and test whether attention problem trajectories predict the risk of a reported attention-deficit/hyperactivity disorder (ADHD) diagnosis. METHODS: We studied 608 infants from the Neonatal Neurobehavior and Outcomes in Very Preterm Infants (NOVI) Study, a prospective, multisite study of infants born <30 weeks of GA. Parents reported on child attention problems at ages 2, 3, 4, and 5 years using the Child Behavior Checklist and the Behavior Assessment System for Children. Sociodemographic and medical characteristics were assessed via maternal interview and medical record review. Neurobehavioral characteristics were determined using neonatal and 2-year assessments. Parent report of child ADHD diagnosis was obtained. We used latent growth curve (LGC) modeling to test our study aims. RESULTS: A linear LGC model provided the best fit to the data. The average trajectory of attention problems evidenced low initial levels of symptoms and little change over time, yet there was significant heterogeneity in both initial levels and change over time. Individual differences in trajectory parameters were associated with sociodemographic, medical, environmental, and neurobehavioral characteristics. Children with higher initial levels of attention problems as well as steeper increases in attention problems over time were more likely to have a reported ADHD diagnosis. CONCLUSIONS: There is significant heterogeneity in trajectories of attention problems from age 2 to 5 in children born <30 weeks of GA and these differences have clinical relevance. These data could inform follow-up guidelines for preterm infants.
Additional file 12 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 12: eTable 10. Association of changes in frailty status with cardiovascular death, accounting for competing risk by non-cardiovascular death.
Could Present Laws Legitimately Bind Future Generations? A Normative Analysis of the Jeffersonian Model
Creators: name: Agmon, Shai
Publisher: name: Intergenerational Justice Review
Year: 2016

description: Thomas Jefferson’s famous proposal, whereby a state’s constitution should be re-enacted every 19 years by a majority vote, purports to solve the intergenerational problem caused by perpetual constitutions: namely that laws which were enacted by people who are already dead bind living citizens without their consent. I argue that the model fails to fulfil its own normative consent-based aspirations. This is because it produces two groups of people who will end up living under laws to which they did not give their consent: (a) citizens who reach the voting age after the re-enactment process; (b) citizens who did not assent to being obliged by the majority vote’s results. I reject possible responses to my argument by showing that they result in making the model either impractical or redundant. The remainder of the paper discusses whether implementing the model would enhance the consent-based legitimacy of the modern state.
description: Intergenerational Justice Review, Vol 9, No 2 (2016): Constitutions as Intergenerational Contracts: Flexible or fixed?
A simple phylogenetic approach to analyze hypermutated HIV proviruses reveals insights into their dynamics and persistence during antiretroviral therapy
Creators: name: Goldstein, Harris
name: Kuniholm, Mark H
name: Shahid, Aniqa
name: Aouizerat, Bradley
name: Ofotokun, Igho
name: Joy, Jeffrey B
name: Fischl, Margaret A
name: MacLennan, Signe
name: Brumme, Zabrina L
name: Dapp, Michael J
name: Archin, Nancie M
name: Gange, Stephen
name: Jones, Bradley R
name: Anastos, Kathryn
name: Kassaye, Seble
name: Duncan, Maggie C
Publisher: name: Oxford University Press (OUP)
Year: 2024

description:
Hypermutated proviruses, which arise in a single HIV replication cycle when host antiviral APOBEC3 proteins introduce extensive G-to-A mutations throughout the viral genome, persist in all people living with HIV receiving antiretroviral therapy (ART). But, hypermutated sequences are routinely excluded from phylogenetic trees because their extensive mutations complicate phylogenetic inference, and as a result we know relatively little about their within-host evolutionary origins and dynamics. Using >1400 longitudinal single-genome-amplified HIV env-gp120 sequences isolated from six women over a median 18 years of follow-up − including plasma HIV RNA sequences collected over a median 9 years between seroconversion and ART initiation, and >500 proviruses isolated over a median 9 years on ART − we evaluated three approaches for masking hypermutation in nucleotide alignments. Our goals were to 1) reconstruct phylogenies that can be used for molecular dating and 2) phylogenetically infer the integration dates of hypermutated proviruses persisting during ART. Two of the approaches (stripping all positions containing putative APOBEC3 mutations from the alignment, or replacing individual putative APOBEC3 mutations in hypermutated sequences with the ambiguous base R) consistently normalized tree topologies, eliminated erroneous clustering of hypermutated proviruses, and brought env-intact and hypermutated proviruses into comparable ranges with respect to multiple tree-based metrics. Importantly, these corrected trees produced integration date estimates for env-intact proviruses that were highly concordant with those from benchmark trees that excluded hypermutated sequences, supporting the use of these corrected trees for molecular dating. Subsequent molecular dating of hypermutated proviruses revealed that these sequences spanned a wide age range, with the oldest ones dating to shortly after infection. This indicates that hypermutated proviruses, like other provirus types, begin to be seeded into the proviral pool immediately following infection, and can persist for decades. In two of the six participants, hypermutated proviruses differed from env-intact ones in terms of their age distributions, suggesting that different provirus types decay at heterogeneous rates in some hosts. These simple approaches to reconstruct hypermutated provirus’ evolutionary histories reveal insights into their in vivo origins and longevity, towards a more comprehensive understanding of HIV persistence during ART.
Constitutions, Democratic Self-Determination and the Institutional Empowerment of Future Generations: Mitigating an Aporia
Creators: name: Rose, Michael
Publisher: name: Intergenerational Justice Review
Year: 2016

description: Is the self-determination of future generations impeded by lasting constitutions, as Thomas Jefferson suggests? In this article it is not only argued that the opposite is true, but also that the question misses the point. It is demonstrated that the very demand for future generations’ full self-determination is self-contradictory, and that it is impossible to achieve. Applying the all-affected principle to future generations, it is shown that we will always affect them, and that we should employ an attitude of “reflective paternalism” towards them. With the help of institutions reviewed in this article, the interests of future generations could be introduced into today’s political decision-making process. The role of constitutions is to provide the prerequisites for democratic self-determination and potentially also to facilitate the institutional empowerment of future generations.
description: Intergenerational Justice Review, Vol 9, No 2 (2016): Constitutions as Intergenerational Contracts: Flexible or fixed?
Additional file 13 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 13: eTable 11. Association of changes in frailty status with cardiovascular death and all-cause mortality, after excluding participants with some comorbidities.
Youth and Politics: Political Education and Participation among Youth (Aydin Gürlevik, Klaus Hurrelmann and Christian Palentien (eds.): Jugend und Politik: Politische Bildung und Beteiligung von Jugendlichen)
Creators: name: Wittmaack, Christof
Publisher: name: Intergenerational Justice Review
Year: 2016

description: No abstract
description: Intergenerational Justice Review, Vol 9, No 2 (2016): Constitutions as Intergenerational Contracts: Flexible or fixed?
Additional file 14 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 14: eTable 12. Association of changes in frailty status with cardiovascular death, after considering deaths of unknown reasons as cardiovascular death.
Associations Between Dietary Patterns and Quality of Life in a Longitudinal Cohort of Colorectal Cancer Survivors
Creators: name: Figueiredo, Jane C.
name: Gigic, Biljana
name: Gudenkauf, Lisa M.
name: Siegel, Erin M.
name: Playdon, Mary C.
name: Toriola, Adetunji T.
name: Oswald, Laura B.
name: Jim, Heather S. L.
name: Hoobler, Rachel
name: Hoogland, Aasha I.
name: Byrd, Doratha A.
name: Li, Xiaoyin
name: Small, Brent J.
name: Shibata, David
name: Greathouse, K. Leigh
name: Crowder, Sylvia L.
name: Smith, Kristen S.
name: Ulrich, Cornelia M.
name: Peoples, Anita R.
name: Gonzalez, Brian D.
name: Li, Christopher I.
Publisher: name: MDPI
Year: 2024

description:
Purpose: To characterize dietary patterns and examine associations with cross-sectional and longitudinal changes in quality of life (QOL) over approximately one year after colorectal cancer (CRC) diagnosis. Methods: The ColoCare Study is an international, multi-center, prospective cohort study of newly diagnosed CRC survivors of any stage. A subset of participants with CRC in the United States completed patient-reported outcome measures at 6- and 12-months post-enrollment, including the Food Frequency Questionnaire (FFQ) and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Dietary patterns at 6 months (around the time of treatment completion) were identified using Principal Component Analysis (PCA) with varimax rotation. Adherence scores were calculated for participants within each dietary pattern, with higher scores indicating higher adherence. Mixed models were used to examine the effect of each dietary pattern on changes in QOL at 6- and 12-month follow-ups, controlling for cancer stage, biological sex, body mass index (BMI), smoking status, and age. Results: Participants (N = 174) were, on average, 56 ± 14 years old and were mostly female (51.5%), stage III or IV (51.7%), never smokers (60.2%), non-Hispanic (97.1%), and White (83.3%) with a BMI of 27.9 ± 6.1 kg/m2. PCA revealed two emerging dietary patterns: “Western diet”, characterized by processed meats, refined grains, and sugars, and “Prudent diet” characterized by lean proteins, fruits, and vegetables. Higher adherence to a Western diet was associated with worse social functioning at 6-month follow-up (FE = −12.6, p = 0.010). Loss of appetite from 6 to 12 months was associated with higher adherence to both the Western and Prudent dietary patterns (FE = 1.5, p = 0.044; FE = 1.3, p = 0.046, respectively). Neither dietary pattern was associated with global QOL score at 6- or 12-month follow-up (p’s > 0.05). Conclusions: Among CRC survivors in the United States, the Western diet was concurrently associated with worse social functioning. Loss of appetite was reported by CRC survivors following both dietary patterns, suggesting that loss of appetite may be a global experience for CRC survivors during this timeframe. Further research is needed to understand specific social challenges experienced by CRC survivors and develop supportive care interventions to address appetite and nutritional concerns.
title: Außenpolitik Nordkoreas unter besonderer Berücksichtigung der Juche-Ideologie
Creators: name: Lösch, Thomas
Year: 2008

description: Die Außenpolitik Nordkoreas unter besonderer Berücksichtigung der Juche-Ideologie: Wie schafft es Nordkorea trotz seiner ökonomischen Probleme und seiner oberflächlich betrachteten Nichtkompatibilität innerhalb „internationalen Staatengemeinschaft“ zu Überleben? Der Grund liegt neben einer starken innenpolitischen Repression in der massiven wirtschaftlichen Unterstützung aus dem Ausland. Zu den größten wirtschaftlichen Wohltätern gehört neben China und Südkorea auch der ideologische Hauptfeind USA. In der Arbeit habe ich versucht, die Handlungsmuster, Veränderungen und Brüche in der nordkoreanischen Außenpolitik seit Gründung der DVRK aufzeigen. Ich habe für meine Arbeit die Form der kritischen Deskription gewählt. Um die Politik eines Landes zu verstehen ist es wichtig sich mit der Geschichte und Kultur auseinander zu setzen. Hier habe ich mich die Methode einer historisch-empirischen Rekonstruktion angewandt. Der Schwerpunkt der Arbeit liegt auf der außenpolitischen Auseinandersetzung um das nordkoreanische Atomwaffenprogramm. Kim Il Sung der nordkoreanische Langzeitpräsident entwickelte eine eigene politische Philosophie, die Juche-Ideologie. Kern dieser Ideologie ist das Streben nach Souveränität. Die Führung der DVRK trachtet danach, weder ökonomisch noch politisch von anderen Ländern abhängig zu sein. Die Führung des Landes will keinerlei politische Veränderungen. Nordkorea braucht sein Atomprogramm um humanitäre Hilfslieferungen erpressen zu können. Andererseits ist aus Sicht der nordkoreanischen Führung, das Atomprogramm der einzige militärische Schutz vor den USA. Kein anderes Land, hat aus unterschiedlichen Gründen ein Interesse am Untergang der DVRK. Die Auseinandersetzung um das nordkoreanische Atomprogramm wird in bisheriger form noch einige Zeit weitergehen.
民营参与正在为中国对非洲的投资带来变化
Creators: Shen, Xiaofang
Publisher: name: Columbia University
Year: 2013
Subjects: Finance
International relations

description: 2012年8月，美国国务卿希拉里克林顿不加掩饰地批评了中国在非洲的影响力，号召非洲国家防范那些“进入非洲贿赂官员，掠夺自然资源而去”的国家。中国官方新闻机构--新华社立即反驳说：克林顿关于中国“出于自身利益”榨取非洲财富的言论完全与事实不符。
Microbial solutions must be deployed against climate catastrophe
Creators: name: Makhalanyane, Thulani P
name: Ventosa, Antonio
name: Voolstra, Christian R
name: Gregory, Ann
name: Bavoil, Patrik M
name: Jiao, Nianzhi
name: Hugenholtz, Philip
name: Häggblom, Max
name: Peixoto, Raquel
name: Wang, Fengping
name: Gilbert, Jack A
name: Salles, Joana Falcao
name: Wang, Yinzhao
name: Stein, Lisa Y
name: Agbodjato, Nadège Adoukè
name: Lennon, Jay T
name: Amin, Shady A
name: Miller, Virginia
Publisher: name: Oxford University Press (OUP)
Year: 2024

description:
The climate crisis is escalating. A multitude of microbe-based solutions have been proposed (Table1), and these technologies hold great promise and could be deployed along with other climate mitigation strategies. However, these solutions have not been deployed effectively at scale. To reverse this inaction, collaborators across different sectors are needed—from industry, funders and policymakers—to coordinate their widespread deployment with the goal of avoiding climate catastrophe. This collective call from joint scientific societies, institutions, editors and publishers, requests that the global community and governments take immediate and decisive emergency action, while also proposing a clear and effective framework for deploying these solutions at scale.
Stratégies pour mieux encadrer les étudiant(e)s à distance lors d'activités de lecture et améliorer leur littératie
Creators: name: Centre de pédagogie universitaire
Publisher: name: Université de Montréal, Centre de pédagogie universitaire
Year: 2021
Subjects: Formation à distance
Lecture
Littératie
Enseignement à distance
Pédagogie universitaire
Enseignement universitaire
Lecture (Enseignement supérieur)
Lecture--Relation avec les matières d'enseignement
Compréhension de la lecture

description: Document qui propose des stratégies et des outils à l'intention des enseignants pour mieux encadrer les activités de lecture des étudiants et mieux soutenir ces derniers dans le développement de leurs habiletés de lecture, de façon générale et dans leur domaine spécifique d'études.
description: Ressources éducatives libres

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Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction
Creators: name: Reis, Kadri
name: Jónsdóttir, Ingileif
name: Skuladóttir, Astros Th.
name: Stefansson, Kari
name: Stefansson, Hreinn
name: Meleka Hanna, Rafael
name: Palotie, Aarno
name: Awasthi, Swapnil
name: Gregersen, Peter K.
name: Elnahas, Abdelrahman G.
name: Kaprio, Jaakko
name: Mergenthaler, Philipp
name: Leypoldt, Frank
name: Meisel, Andreas
name: Fontanillas, Pierre
name: Levey, Daniel F.
name: Shekhar, Sudhanshu
name: Esko, Tõnu
name: Paschou, Peristera
name: Tannemaat, Martijn R.
name: Heilbron, Karl
name: Davis, Lea K.
name: Asbjornsdottir, Bergrun
name: Stein, Murray B.
name: Straub, Peter
name: Braun, Alice
name: Verschuuren, Jan J.G.M.
name: Kraft, Julia
name: Panagiotaropoulou, Georgia M.
name: Gelernter, Joel
name: Stascheit, Frauke
name: Stein, Maike
name: Hoffmann, Sarah
name: Lehnerer, Sophie
name: Huijbers, Maartje G.
name: Kuhlenbäumer, Gregor
name: Ripke, Stephan
name: Palviainen, Teemu
name: Koromina, Maria
name: Topaloudi, Apostolia
Publisher: name: Springer Nature
Year: 2024

description:
Myasthenia gravis (MG) is a rare autoantibody-mediated disease affecting the neuromuscular junction. We performed a genome-wide association study of 5708 MG cases and 432,028 controls of European ancestry and a replication study in 3989 cases and 226,643 controls provided by 23andMe Inc. We identified 12 independent genome-wide significant hits (P < 5e−8) across 11 loci. Subgroup analyses revealed two of these were associated with early-onset (at age <50) and four with late-onset MG (at age ≥ 50). Imputation of human leukocyte antigen alleles revealed inverse effect sizes for late- and early-onset, suggesting a potential modulatory influence on the time of disease manifestation. We assessed the performance of polygenic risk scores for MG, which significantly predicted disease status in an independent target cohort, explaining 4.21% of the phenotypic variation (P = 5.12e−9). With this work, we aim to enhance our understanding of the genetic architecture of MG.
Additional file 15 of Association of changes in frailty status with the risk of all-cause mortality and cardiovascular death in older people: results from the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Creators: name: Wang, Ziqiong
name: Ruan, Haiyan
name: Li, Liying
name: Song, Ningying
name: He, Sen
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 15: eTable 13. Association of changes in frailty status with cardiovascular death and all-cause mortality after multiple imputationa.
BioExcel Webinar #66: Efficient (GROMACS+)CP2K compute resource usage for QM/MM simulation of biomolecular systems
Creators: name: Proeme, Arno
name: Judge, Holly
Publisher: name: Zenodo
Year: 2022
Subjects: webinar

description: Hybrid quantum/classical (QM/MM) simulation of biomolecular systems has grown in popularity in recent years, facilitated in part by the availability of software such as the GROMACS-CP2K and GROMACS-CPMD interfaces developed within BioExcel, which couple GROMACS with the CP2K and CPMD quantum chemistry / electronic structure codes. Performing productive QM/MM simulation of biomolecular systems requires researchers to not only carefully choose suitable QM and QM-MM coupling treatments – a topic covered in depth in our workshop on Best Practices in QM/MM simulation of Biomolecular Systems – but also to consider how best to make use of available computational resources, which are needed mainly for costly QM calculations. Available computational resources may constrain the choice of treatment that is feasible and hence the quality of results obtained, which may amount not merely to a quantitative difference in accuracy but even to qualitatively different conclusions regarding structure or function. Understanding how the QM/MM simulation software employed can best make use of available hardware including processors (CPUs) and accelerators (GPUs) has the potential to not only improve efficient utilisation of these resources but also to significantly accelerate research and individual researcher productivity. Moreover, knowing what computational resources would be needed to pursue a given treatment helps justify and obtain access to high-performance computing (HPC) resources at an institutional, regional, or national level, including the largest facilities available to researchers in the form of – in the EU – supercomputing infrastructure provided through PRACE and EuroHPC. With that in mind and in order to assist researchers using or considering using CP2K – with GROMACS or as a standalone application – for QM/MM simulation of biomolecular systems, we provide in this webinar a brief overview of the parallel performance of CP2K on hardware commonly found on modern HPC machines for a range of biomolecular systems and QM treatments that together make up the BioExcel QM/MM Benchmark Suite. This overview is intended to function as a rough reference and a useful starting point to guide researchers towards obtaining good performance on available hardware for their system of interest, and/or to help plan future work that includes access to and increased usage of HPC resources.
How the private sector is changing Chinese investment in Africa?
Creators: Shen, Xiaofang
Publisher: name: Columbia University
Year: 2013
Subjects: Finance
International relations

description: In August 2012, US Secretary of the State Hilary Clinton offered a thinly veiled criticism of China’s role in Africa, calling upon African countries to guard against those that “come in, take out natural resources, pay off leaders and leave.”The Chinese official news agency, Xinhua, retorted immediately that “Clinton’s implication that China has been extracting Africa’s wealth for itself is utterly wide of the truth.”