Herpes zoster vaccination: Primary care provider knowledge, attitudes, and practices
Creators: name: Stempniewicz, Nikita
name: Davenport, Eric
name: Wang, Jinyi
name: Sweeney, Carolyn
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Primary care providers (PCPs) play a key role in vaccine recommendations and uptake, but limited information exists about PCP knowledge, attitudes, and practices regarding herpes zoster (HZ) vaccination. Clinical trials have shown that recombinant zoster vaccine (RZV) significantly reduces the risk of developing HZ. Hence, RZV is recommended by the US Advisory Committee on Immunization Practices (ACIP) for adults aged ≥50 years and immunocompromised adults aged ≥19 years. However, RZV uptake varies across age groups, and is lower for adults aged 50–59 compared to those aged ≥60 years. Using a cross-sectional web-based survey, this study described provider knowledge of HZ risk factors, ACIP recommendations, attitudes toward HZ vaccination, and HZ vaccination practices/barriers. Among 301 licensed PCPs in the US, knowledge of HZ risk factors was high, but only 29% were fully aware of the ACIP recommendations. PCPs indicated that HZ vaccination was important for patients aged 50–59, 60–69, and ≥70 years, with importance increasing with advancing age. During a typical week, an average of 44% (standard deviation = 32%) of PCPs reported initiating a conversation about HZ vaccination among adults aged 50–59 years. Key perceived barriers to recommending HZ vaccines to adults were contraindications and insufficient time to assess risk factors, while perceived HZ vaccine administration challenges included patients’ out-of-pocket costs and lack of motivation. Results suggest that PCPs may benefit from updated information about ACIP recommendations, while both patients and providers may benefit from streamlining the vaccination process and educational efforts focused on addressing perceived barriers. Shingles (herpes zoster) typically causes a painful rash on the torso, and people often develop pain at the rash site, which can last for several months. Shingles is more common in older people and those whose immune system is compromised. To help prevent shingles, a vaccine called recombinant zoster vaccine (RZV) is recommended in the United States (US) for adults aged 50 years and over and for immunocompromised adults 19 years and over. However, people aged 50–59 years are less likely to have received shingles vaccination compared to older age groups. In this study, 301 primary care providers (PCPs) in the US completed a survey about shingles and vaccination. Most PCPs knew the risk factors for shingles, but only 29% were fully aware of the shingles vaccine recommendations in the US. PCPs generally believed in the importance of vaccinating adults 50 years and over against shingles, with the perceived importance increasing with the patient’s age. The PCPs identified various barriers to shingles vaccination, but interestingly, some of these barriers were based on outdated information, particularly regarding out-of-pocket costs, which have been largely addressed by recent changes in legislation. Providing updated information to PCPs about the current vaccination recommendations for shingles prevention and addressing misconceptions could help to improve shingles prevention. Additionally, educating patients about shingles could further support improvements, and help reduce the overall burden of shingles.