cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The impact of Gdown1, IE2, and human cytomegalovirus infection on transcription
Creators: name: Ball, Christopher Brooks
Publisher: name: University of Iowa
Year: 2023
Subjects: Chromatin
Human Cytomegalovirus
public abstract
Mitosis
Transcription

description: RNA polymerase II (Pol II) transcribes all protein-coding messenger RNAs. To ensure proper gene expression, Pol II is subject to control mechanisms that dictate the location, timing, and magnitude of transcription. Dysregulation of Pol II transcription is associated with loss of cell identity and myriad disease states, and the Pol II transcriptional machinery is exploited by many viruses to drive productive viral gene expression. The research presented here explores the regulation of Pol II transcription at the level of basic mechanism and in the context of viral infection. The function of Gdown1, a reported Pol II sub-stoichiometric subunit, was investigated. New reagents enabling the careful study of Gdown1 were developed using CRISPR-Cas9 genome engineering. I showed, in contrast to previous reports, that Gdown1 is primarily cytoplasmic, largely not associated with nuclear Pol II, and regulated by nuclear export. Consistently, acute depletion of Gdown1 is associated with minimal direct effects on transcription, as assessed by PRO-Seq. Gdown1-depleted cells exhibited aberrant mitoses, which was linked to a potential role for Gdown1 in mitotic transcriptional repression. Evidence was also provided that Gdown1 modulates the functions of Pol II productive elongation factors.
description: The regulation of transcription by Human Cytomegalovirus transcription factor IE2 was also explored. Using PRO-Seq to measure nascent transcription, I showed that IE2 functions as a transcriptional activator, repressor, and elongation modulator. These properties of IE2 were linked to functional occupancy of a defined IE2 consensus motif. A distance-dependence paradigm was uncovered that relates to whether bound IE2 activates or represses its target viral promoters. Use of novel chromatin immunoprecipitation approaches revealed a functional association between IE2 and nucleosomes that facilitates transcriptional repression. Overall, my research greatly extended our understanding of IE2 mechanism of action.
description: The impact of Human Cytomegalovirus (HCMV) infection on host gene transcription by Pol I, II, and III was investigated through the generation and analysis of PRO-Seq datasets that span the course of lytic infection. I uncovered that late HCMV infection is associated with globally increased rates of release of Pol II into productive elongation. Evidence was also provided that HCMV infection alters Pol I transcription elongation. Finally, I showed that HCMV infection dramatically impacts Pol III transcription of tRNAs. These results revealed unexpected new insights into how HCMV alters transcription of the host genome.
Practical application of spatial ecosystem service models to aid decision support
Creators: name: Hoyer, Christian
name: Zulian, Grazia
name: Stange, Erik
name: Woods, Helen
Publisher: name: My University
Year: 2018

description: Ecosystem service (ES) spatial modelling is a key component of the integrated assessments designed to support policies and management practices aiming at environmental sustainability. ESTIMAP ("Ecosystem Service Mapping Tool") is a collection of spatially explicit models, originally developed to support policies at a European scale. We based our analysis on 10 case studies, and 3 ES models. Each case study applied at least one model at a local scale. We analyzed the applications with respect to: the adaptation process; the "precision differential" which we define as the variation generated in the model between the degree of spatial variation within the spatial distribution of ES and what the model captures; the stakeholders' opinions on the usefulness of models. We propose a protocol for adapting ESTIMAP to the local conditions. We present the precision differential as a means of assessing how the type of model and level of model adaptation generate variation among model outputs. We then present the opinion of stakeholders; that in general considered the approach useful for stimulating discussion and supporting communication. Major constraints identified were the lack of spatial data with sufficient level of detail, and the level of expertise needed to set up and compute the models. © 2017 The Authors. Published by Elsevier B.V.
CD4 T cells as targets for the cytotoxic T lymphocyte assay: A study of enhancers of HIV-1 infection in the target cell preparation.
Creators: name: Fullmer, Elizabeth H.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Health Sciences, Immunology.

description: My objective was to establish the conditions necessary to measure cytotoxic T lymphocyte (CTL) activity. The approach was to clone peripheral blood mononuclear cells (PBMC) from HIV-1$\sp+$ asymptomatic patients to obtain CD8$\sp+$ clones and test these cells against autologous CD4$\sp+$ T lymphoblasts. I also tested the following enhancers of viral infectivity: DEAE-Dextran (DD), Polybrene and Tumor Necrosis Factor-Alpha (TNF$\alpha$) in normal T cells and HUT-78 cells and found that DD greatly increases infection when used as pretreatment and during infection at 10 $\mu$g/ml. Polybrene (2.5-5 $\mu$g/ml) also increases infection when used as pretreatment and during infection but not as much as DD. It proved to be less toxic than DD and would be useful when a slow, less acute infection is desired. The effect of TNF $\alpha$ at 5 ng/ml was not noticeable in normal T cells the first few days after the infection but the infection increased six or seven days later. TNF$\alpha$ did not have any significant effect on the HUT-78 cell line. The improved infection protocol with the use of enhancers will be useful in the production and maintenance of high titer virus stocks in the laboratory and in the infection of sensitive target cells for CTL assays. (Abstract shortened by UMI.)
Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage
Creators: name: Hemmati-Sadeghi, Shabnam
name: Ringe, Jochen
name: Dehne, Tilo
name: Haag, Rainer
name: Sittinger, Michael
Publisher: name: Freie Universität Berlin
Year: 2018
Subjects: subject: hyaluronic acid
subject: osteoarthritis
subject: in vitro model
subject: microarray
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
subject: 500 Naturwissenschaften und Mathematik::540 Chemie

description: The aim of this study is to identify gene expression profiles associated with hyaluronic acid (HA) treatment of normal and osteoarthritis (OA)-like tissue- engineered cartilage. 3D cartilage micromasses were treated with tumour necrosis factor-α (TNF-α) (OA-inducer) and/or HA for 7 days. Viability was examined by PI/FDA staining. To document extracellular matrix (ECM) formation, glycosaminoglycans (GAG) were stained with Safranin-O and cartilage-specific type II collagen was detected immunohistochemically. Genome-wide gene expression was determined using microarray analysis. Normal and OA-like micromasses remained vital and showed a spherical morphology and homogenous cell distribution regardless of the treatment. There was no distinct difference in immunolabeling for type II collagen. Safranin-O staining demonstrated a typical depletion of GAG in TNF-α-treated micromasses (−73%), although the extent was limited in the presence of HA (−39%). The microarray data showed that HA can influence the cartilage metabolism via upregulation of TIMP3 in OA-like condition. The upregulation of VEGFA and ANKRD37 genes implies a supportive role of HA in cartilage maturation and survival. The results of this study validate the feasibility of the in vitro OA model for the investigation of HA. On the cellular level, no inhibiting or activating effect of HA was shown. Microarray data demonstrated a minor impact of HA on gene expression level.
MPEC 2025-E60 : 2025 EN
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 EN

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
On the efficient implementation and parameter selection for TDA Mapper
Creators: name: Rooke, Ethan A.
Publisher: name: University of Iowa
Year: 2023
Subjects: Mapper
Parameter
Persistence
TDA
Visualization
public abstract
Filtration

description: Mapper is a topological data analysis algorithm used to visualize high dimensional data. Mapper is given a dataset X, a lens function f : X → R, a cover,and clustering algorithm and produces a graph. This graph encodes topological data about X.
description: A primary concern with Mapper is parameter selection: out of the limitless choices one has for covers and lens functions, how does one choose what to use? How do we know that the output obtained from Mapper is generally meaningful and not the result of serendipity on behalf of our choices? Previous work by Bungula showed that Mapper complexes exhibit a stable filtration for some parameter choices. This presents a possible way forward adapting the techniques from persistent homology to Mapper.
description: The aim of this thesis is threefold. First, we aim to present algorithms that compute the filtration on the Mapper complex, enabling integration with persistent homology software. Second, we aim to provide tools for visualizing this filtration in addition to computing the persistence. Finally, we aim to address the question of efficient implementation of the Mapper algorithm.
A Quiet Revolution? Youth Perception of State and Church Ideology in Zaire
Creators: name: Romaldi, Christa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Religion, History of.
subject: Geography.
subject: Sub Saharan Africa Studies.

description: This thesis focuses on the power struggle between Mobutu's administration and the Catholic Church as it played out in the realm of education. In particular, it focuses on how state ideology, meaning authenticity and Mobutism, pervaded education through textbooks and teaching materials in 1970s Zaire and how the Catholic Church attempted to resist state ideology through education as well. Discourse analysis was used to determine how state dogma and Church opposition were disseminated to youth via educational materials. Furthermore, I examine how and why youth responded to this power struggle through the examination of painting, music and literature created by the 1970s cohort as they aged. Again, discourse analysis is used to understand the meanings conveyed through the art. Youth, I argue, have rejected Mobutu and his ideologies and remain uncertain, perhaps even suspicious, of the Catholic Church's role in Zaire (Democratic Republic of the Congo).
nIFTy cosmology: Galaxy/halo mock catalogue comparison project on clustering statistics
Creators: name: Chuang, Chia-Hsun
name: Zhao, Cheng
name: Prada, Francisco
name: Munari, Emiliano
name: Avila, Santiago
name: Izard, Albert
name: Kitaura, Francisco-Shu
name: Manera, Marc
name: Monaco, Pierluigi
name: Murray, Steven
name: Knebe, Alexander
name: Scóccola, Claudia G.
name: Yepes, Gustavo
name: Garcia-Bellido, Juan
name: Marin Perucci, Felipe
name: Müller, Volker
name: Skibba, Ramin
name: Crocce, Martin
name: Fosalba, Pablo
name: Gottlöber, Stefan
name: Klypin, Anatoly A.
name: Power, Chris
name: Tao, Charling
name: Turchaninov, Victor
Publisher: name: Swinburne
Year: 2024

description: We present a comparison of major methodologies of fast generating mock halo or galaxy catalogues. The comparison is done for two-point (power spectrum and two-point correlation function in real and redshift space), and the three-point clustering statistics (bispectrum and three-point correlation function). The reference catalogues are drawn from the BigMultiDark N-body simulation. Both friend-of-friends (including distinct haloes only) and spherical overdensity (including distinct haloes and subhalos) catalogues have been used with the typical number density of a large volume galaxy surveys. We demonstrate that a proper biasing model is essential for reproducing the power spectrum at quasi-linear and even smaller scales. With respect to various clustering statistics, a methodology based on perturbation theory and a realistic biasing model leads to very good agreement with N-body simulations. However, for the quadrupole of the correlation function or the power spectrum, only the method based on semi-N-body simulation could reach high accuracy (1 per cent level) at small scales, i.e. r < 25 h-1 Mpc or k > 0.15 h Mpc-1. Full N-body solutions will remain indispensable to produce reference catalogues. Nevertheless, we have demonstrated that the more efficient approximate solvers can reach a few per cent accuracy in terms of clustering statistics at the scales interesting for the large-scale structure analysis. This makes them useful for massive production aimed at covariance studies, to scan large parameter spaces, and to estimate uncertainties in data analysis techniques, such as baryon acoustic oscillation reconstruction, redshift distortion measurements, etc.
Exploring the effect of a lifestyle survivorship program on psychosocial mechanisms of action and cancer-related health outcomes among adult cancer survivors
Creators: name: Steinke, Lauren
Publisher: name: University of Iowa
Year: 2023
Subjects: Behavior change
Cancer Survivors
Health coaching
Lifestyle-based
public abstract

description: Introduction
description: The American Cancer Society (ACS) recommends cancer survivors follow the recommended guidelines for physical activity (PA), diet, and sleep to improve cancer-related health outcomes. The ACS recommends healthcare systems establish comprehensive survivorship programs supportive of engaging in healthy lifestyle behaviors following active treatment. However, few lifestyle-focused programs exist for addressing the unique needs of cancer survivors. The purpose of this project is to explore the effect of a lifestyle-based, health coaching program on cancer-related health outcomes and psychosocial mechanisms of action among young and middle-aged adult cancer survivors.
description: Methods
description: Young and middle-aged cancer survivors (
description: Results
description: A total of 42 individuals consented to the study, and 36 participants completed baseline testing. A total of 30 participants (80% female; mean body mass index (BMI) =31.0+5.8 kg/m2; mean age=42.0+10.8 years) completed the entire study protocol. We observed significant improvements in the following psychosocial mechanisms of action: behavioral skills (d = 2.04, p < 0.01) habits (d = 0.52, p < 0.01) and identities (d = 0.72, p = 0.01). For cancer-related health outcomes, we observed significant improvements in fatigue (d = 0.86, p = 0.03), sleep disturbance (d = 0.95, p = 0.01), social roles (d = 0.68, p = 0.01), and global health (d = 0.99, p < 0.01). We observed significant worsening in pain interference (d = -1.01, p < 0.01). Participants found this program to be enjoyable and helpful for improving health. Health coaching and remote delivery were rated as the most satisfactory of all the program features.
description: Discussion
description: These findings suggest adult cancer survivors improved several targeted psychosocial constructs and reported improvements in important cancer-related health outcomes of fatigue, sleep disturbance, the ability to participate in social roles, and global health. Participants gained skills to maintain behavior change, as indicated by improvements in behavioral skills (goal setting, self-monitoring, action planning), health habits, and health identities. Decreased fatigue and sleep disturbance, and increased ability to participate in social roles and global health suggest important health improvements for participants. Participants found the program to be acceptable and satisfactory to participate. Further investigation is needed to improve the program before advancing to a phase IIb pilot test.
The ALS8-associated P56S mutation of VAPB alters ER morphology and ER function
Creators: name: Tran, Duvinh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biology, Neuroscience.

description: Amyotrophic lateral sclerosis is a neurodegenerative disease that affects motor neurones of the central nervous system leading to the loss of voluntary muscle control. The objective of this study is to characterize the cellular effects of the P56S mutation in the VAPB gene identified in ALS8, and how these might lead to neurodegeneration. Over-expression ofVAPB-P56S induced formation of expanded endoplasmic reticulum tubules and caused nuclear envelope defects resulting in functional deficits. The mutation inhibited transport of correctly folded membrane proteins from the ER to the Golgi complex and dampened activation of the IRE1 and ATF6 signaling pathways of the unfolded protein response. VAPs interact with lipid binding proteins containing a FFAT motif and co-expression of a FFAT motif resolved the morphological and functional deficits, suggesting that VAPB-P56S might be a gain of toxic function and that the FFAT motif acts as a competitive agonist in counteracting this toxic effect.
Peering policy gaps with the National Broadband Network
Creators: name: Hackett, Simon
Publisher: name: Swinburne
Year: 2024

description: Deploying a 'superfast' national tail circuit network (i.e. the National Broadband Network) will highlight other bottlenecks in information flow that currently exist between voice and data service providers in Australia, unless those bottlenecks are also addressed. This paper highlights the need for appropriately symmetrical peering arrangements to be enforced, for both voice and data services, between all NBN Service Provider networks.
Ventricular‐Vascular Coupling in Marfan and Non‐Marfan Aortopathies
Creators: name: Loeper, Farina
name: Oosterhof, Jantine
name: Van Den Dorpel, Mark
name: Van Der Linde, Denise
name: Lu, Yaxin
name: Robertson, Elizabeth
name: Hambly, Brett
name: Jeremy, Richmond
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: aneurysm
subject: β‐blocker
subject: matrix metalloproteinases
subject: mechanics
subject: myocardium
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background: Marfan syndrome (MFS) and familial non–syndromal thoracic aortic aneurysm and dissection (ns‐TAAD) are genetic aortopathies causing aortic dilatation with increased aortic stiffness. Left ventricular (LV) contractility and ventricular‐vascular coupling index (VVI) were compared between MFS and ns‐TAAD and determinants of VVI were investigated. Methods and Results: Patients with MFS (M 57, F 47) and ns‐TAAD (M 72, F 39) were studied by echocardiography and compared with controls (M 77, F 71). Aortic geometry, hemodynamics, LV work, LV contractility (end‐systolic elastance [Ees]), and VVI were documented. Aortic sinuses were equally dilated in MFS (19.7±2.4) and ns‐TAAD (19.8±1.8) compared to controls (16.2±1.4 mm·m−2, P<0.001). Aortic stiffness index was increased in MFS (9.7±5.1) and ns‐TAAD (10.8±4.7) versus controls (5.4±2.0, P<0.01); LV stroke work was unchanged in MFS (436±74) compared to controls (435±60) but increased in ns‐TAAD (492±109 mJ·m−2 P<0.01). The LV Ees was reduced in MFS (1.32±0.19) compared to controls (1.65±0.29 mm Hg·mL−1, P<0.01) but increased in ns‐TAAD (1.83±0.30, P<0.01) and VVI was abnormal in MFS (0.71±0.11) compared to controls (0.62±0.07, P<0.01) and ns‐TAAD (0.62±0.09). Treatment with β‐blockers was associated with partial normalization of VVI in MFS. A VVI ≥0.8 was associated with increased risk of death and heart failure in MFS. Conclusions: Left ventricular contractility and ventricular‐vascular coupling are abnormal in MFS but preserved in ns‐TAAD, and are independent of aortic stiffness, consistent with intrinsic impairment of myocardial contractility in MFS.
РЕКОМЕНДАЦИИ ПО ОЦЕНКЕ ПЕШЕХОДНОЙ ДОСТУПНОСТИ
Creators: name: Пулатова, Зулфия
name: Садиков, Ибрагим
Publisher: name: Zenodo
Year: 2024

description: В данной статье даны рекомендации по оценке пешеходной доступности в разбивке по районам с учетом улично-дорожной сети города Ташкента и по определению ее индекса. В том числе также указывается метод оценки пешеходной доступности с экономической точки зрения, а также расчет экономической прибыли.
The development of powerfulness in male youth through their participation in venturers.
Creators: name: Hanna, Gordon H.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1976
Subjects: subject: Psychology, Social.

description: Youth are seen as existing in a psycho-social moratorium and seem to be becoming increasingly alienated from our society. Rotter suggests that alienation is related to the variable of internal-external control. Rotter operationalizes his theory in research, but he does not provide an etiology for alienation. Upon examining Rotter's and Keniston's theories, it has been concluded that the two theories are similar, and that Keniston's formulations could be used to extend Rotter's theory by providing it with an etiology. Keniston believes that three societal forces are needed for the development of powerfulness in youth; these forces are presented in detail in this report. The Venturer program of Boy Scouts of Canada is presented as a possible recreational program that helps to develop powerfulness in youth. The program is then considered in light of Keniston's three societal forces, and it is concluded that Venturing does seem to have the necessary elements for the development of powerfulness. Using scores on Rotter's Internal Versus External Control Scale as the dependent variable, the hypothesis teated at the .05 level of significance was that participation in the Venturer program results in greater powerfulness than non-participation in the Venturer program. The research involved a pre-test/post-test design with forty-four Venturers and one hundred six non-Venturers from a large suburban community in Southern Ontario. The results indicated that youth joining the Venturer program have a significantly higher degree of powerfulness when joining Venturers, and also, when the initial difference is statistically controlled with a test of covariance, there is a significant difference in powerfulness between Venturers and non-Venturers over a thirteen month period. This report is of particular importance as it supports the contention that youth participating in the Venturer program develop powerfulness. The rationale for this increase in powerfulness is due to the presence of Keniston's three societal forces. This report also shows how Keniston's etiology of alienation is actually an extension of Rotter's locus of control theory. The findings herein indicate that Venturing is a valuable recreational program that can provide a basis for practical work with adolescents. 1 Gordon H. Hanna, master's thesis submitted to the School of Graduate Studies of the University of Ottawa, Ontario, September, 1976, 128 p.
Umweltbewusstsein in Deutschland 2014
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Nachhaltigkeit
subject: Umweltbewusstsein
subject: Konsum
subject: Wirtschaft
subject: Nachhaltigkeit | Strategien | Internationales
subject: Sustainability | Strategies | International matters

description: Die Studie beweist, dass der Umweltschutz in unserer Bevölkerung einen sehr hohen Stellenwert besitzt. Sie zeigt aber auch, dass wir in unseren Bemühungen nicht nachlassen dürfen. Die Befragten verbinden Umweltthemen in der Tendenz weniger mit aktuellen Problemen, sondern betonen eher die Chancen, die sich langfristig durch konsequenten Umweltschutz ergeben. Nach der sozialen und der inneren Sicherheit ist der Umweltschutz in der Wahrnehmung der Menschen eine der größten Aufgaben, denen wir gegenüberstehen. Die Studie zeigt, dass die Bereitschaft größer wird, das eigene Handeln im Hinblick auf die Umweltauswirkungen zu überprüfen. Für mehr als neun von zehn Deutschen ist es wichtig, so zu leben, dass sie sich mit der Umwelt im Reinen fühlen. Sie sind offen für Alternativen zu ressourcenintensiven und klimaschädlichen Gewohnheiten - zum Beispiel, indem sie auf Bus, Bahn oder das Fahrrad umsteigen. Viele Bürgerinnen und Bürger sind auch dazu bereit, sich in der Gesellschaft für die Umwelt zu engagieren. Das zeigt zum Beispiel die hohe Wertschätzung für die Arbeit der Umweltverbände.
Quelle: www.umweltbundesamt.de

description: Die Studie beweist, dass der Umweltschutz in unserer Bevölkerung einen sehr hohen Stellenwert besitzt. Sie zeigt aber auch, dass wir in unseren Bemühungen nicht nachlassen dürfen. Die Befragten verbinden Umweltthemen in der Tendenz weniger mit aktuellen Problemen, sondern betonen eher die Chancen, die sich langfristig durch konsequenten Umweltschutz ergeben. Nach der sozialen und der inneren Sicherheit ist der Umweltschutz in der Wahrnehmung der Menschen eine der größten Aufgaben, denen wir gegenüberstehen. Die Studie zeigt, dass die Bereitschaft größer wird, das eigene Handeln im Hinblick auf die Umweltauswirkungen zu überprüfen. Für mehr als neun von zehn Deutschen ist es wichtig, so zu leben, dass sie sich mit der Umwelt im Reinen fühlen. Sie sind offen für Alternativen zu ressourcenintensiven und klimaschädlichen Gewohnheiten – zum Beispiel, indem sie auf Bus, Bahn oder das Fahrrad umsteigen. Viele Bürgerinnen und Bürger sind auch dazu bereit, sich in der Gesellschaft für die Umwelt zu engagieren. Das zeigt zum Beispiel die hohe Wertschätzung für die Arbeit der Umweltverbände.
Hydrodenitrogenation of pyridine on nickel oxide-tungsten trioxide-aluminum oxide catalyst.
Creators: name: Anabtawi, Jamal.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1977
Subjects: subject: Engineering, Chemical.

description: The kinetics of hydrodenitrogenation of pyridine over a catalyst containing 6% Ni and 19% W supported on alumina has been investigated in an integral fixed bed tubular reactor at 410 psig. The effect of various variables such as molar ratio, reaction temperature, initial partial pressure of reactants, and residence time on the conversion of pyridine have been studied. The reaction was carried out in a temperature range 120--380°C. The reaction is believed to take place according to the following path: pyridine kov → 3H2 piperidine +pip → +H2 n-pentyl piperidine-pip → +H2 pentane + ammonia. A rate equation for the first reaction namely, hydrogenation of pyridine has been suggested. Hydrogenation of pyridine to piperidine was found to be first order with respect to both pyridine and hydrogen. The apparent rate constant was found to be dependent on the initial partial pressure of pyridine. The rate equation was formulated to be as follows: -ddt pPy= ki+ksR &d1;/H2 P° pPy HPy The activation energy of the reaction and the frequency factor were calculated to be 13.691 K cal/gm mole, and 5.987 x 10-2 gm-molegm-cat-hr N/2m respectively.
The determinants that are associated with women deciding to take long-term preventive hormone replacement evaluated in the context of the decision support framework.
Creators: name: Clark, Heather Diane.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Health Sciences, Obstetrics and Gynecology.

description: Objectives. (1) Primary, to identify factors influencing the decision to take long-term preventive hormone replacement therapy (LTP-HRT) assessed 2 months after the counseling interview with the physician. (2) Secondary, to identify factors influencing the decision to take LTP-HRT assessed after reviewing a decision support intervention and after a counseling interview with their physician and to identify the factors that are associated with women being uncertain regarding the decision to take LTP-HRT. Method. Data, collected from women who were participating in a RCT to evaluate the effectiveness of a decision support intervention, was used to develop multivariate statistical models at three specific time points. The time points were after reviewing the decision support intervention, after a counseling interview with their physician, and 2 months after the counseling interview. The physician was the unit of randomization in the original study and thus multivariate statistical modeling adjusting for correlated observations using Generalized Estimating Equations was utilized. (Abstract shortened by UMI.)
Concrete columns confined with scrap tires.
Creators: name: Bugaldian, Adel Abdulmoula.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Engineering, Civil.

description: One possible alternative to conventional transverse reinforcement is to use scrap tires for column confinement. However, there is currently no experimental data available on the effectiveness of scrap tires as confinement reinforcement. It is the objective of the current research program to conduct experimental and analytical investigation to explore the possibilities of using scrap steel-belted tires as transverse column reinforcement for bridge columns. The experimental investigation included testing six large-scale circular columns, confined with scrap tires, under simulated seismic loading. Three different arrangements of tires were used as confinement reinforcement which allowed the investigation of different parameters of confinement on column behavior. The columns were tested under two different levels of axial load, consisting of 11% or 21% of their concentric capacities. Analyses of columns were also conducted using the computer program COLA, which had been developed for inelastic static analysis of conventionally reinforced concrete columns. It was shown both experimentally and analytically that steel-belted tires can be used effectively to confine concrete in reinforced concrete columns. This new approach eliminates many of the construction difficulties involved in building seismic resistant concrete columns, while protecting steel against corrosion. (Abstract shortened by UMI.)
Frame replenishment coding over noisy channels.
Creators: name: Zhang, Liping.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, Electronics and Electrical.

description: In this thesis, we compare the performances of three frame replenishment coding schemes for noiseless and noisy channel transmission. For the noisy channel case, we propose a combined source-channel coding scheme which provides error protection in order to improve the performance. The three frame replenishment coding techniques are: basic frame replenishment coding (BFR), label replenishment coding using vector quantization (LRVQ) and codeword replenishment coding using vector quantization (CWRVQ). Our simulation results demonstrate that for a noiseless channel, the LRVQ and CWRVQ techniques provide better performance, and tolerance to motion in the picture, compared to BFR technique. However, in the presence of channel noise LRVQ and CWRVQ techniques exhibit high sensitivities, resulting in poor performance. We propose to use a combined source-channel coding technique with three different error protection schemes where the bit rates for the source code and channel code are adjusted so as to minimize the mean square error. Simulation results demonstrate that the three error protection schemes provide a significant improvement in performance for LRVQ and CWRVQ without sacrificing transmission bandwidth. (Abstract shortened by UMI.)
A macroeconometric model of a subsistence economy: The case of Ethiopia.
Creators: name: Taye, Haile Kebret.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: Economics, General.

description: The objective of this study is to analyze the structural and behavioral attributes of a small and open subsistence economy. Using a medium-sized macroeconometric policy model, the study analyses specific structural factors and internal rigidities facing the Ethiopian economy and examines the impacts of various past and recent policies implemented by successive governments. The study addresses the question of the applicability of macroeconometric models for developing countries and uses such a model to examine the structural and institutional peculiarities of a subsistence economy. This study also presents the first macroeconometric policy model of Ethiopia. This model is used to examine the supply constraints and the importance of the exchange rate on the economy. Further the study will attempt to examine the impact of alternative macro policies on the performance of the economy and provide a quantitative framework for further policy analysis. The specific policy issues examined include: One, how was the performance of the Ethiopian economy affected by the policy shift of the mid-seventies? Two, what is the likely impact of the recently implemented devaluation of the domestic currency (birr) on the balance of payments and other economic aggregates? And, three, is there a trade-off between military expenditures and social programs? The key findings are summarized below. Devaluing the currency would: One, have an adverse impact on output growth and, hence, on components of aggregate demand--on private consumption expenditures and on private investment, for instance; two, be inflationary, as would be expected for a small (price taking) open economy; but, three, it would have a positive impact on the current account balance. A reduction in military expenditures: One, would increase total output, and would have a positive net impact on private consumption and investment expenditures; two, suggests the existence of a significant trade-off between military expenditures and expenditures on education and health; and, three, would improve the current account balance since most of the military equipment is imported. No change in policy in the mid-1970s would have: One, increased total output and sectoral outputs, and would have had a positive net impact on private consumption and investment expenditures; two, increased expenditures on education and health; but, three, would have decreased most imports and exports and would have had a net positive impact on the current account balance. (Abstract shortened by UMI.)
Social Capital and its Role in 1930s Drought Adaptation and Migration in Saskatchewan
Creators: name: Laforge, Julia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: History, Canadian.
subject: Geography.

description: This research examines the role that capital, particularly social capital, plays in human adaptation to climate change through migration using the 1930s drought in Saskatchewan as the case study. Exploring the motivations of those who migrated from drought-stricken southern portion of the province to the Aspen Parkland to the north provides an understanding of how farmers and rural communities adapt to extreme climatic conditions. In a period of difficult economic and environmental conditions, when financial resources and formal education were limited for many households, farmers relied heavily on social networks to help them adapt to climate change by informing them about potential migration destinations and by helping them integrate into the new community. This project incorporated in-depth interviews with forty participants who experienced this migration along with archival data and other secondary sources, to develop an understanding of the relationship between social capital, migration, and adaptation. Insights developed through this study may be useful in better understanding future adaptation and migration responses to anthropogenic climate change.
Le bilinguisme fonctionnel du gouvernement ontarien, ou, Les origines et la réception des services en français, 1976-1986.
Creators: name: Piret, Nadine.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Language, Modern.

description: Le gouvernement ontarien, quant a lui, n'a pas adhere aux articles 16 a 20 de la Charte canadienne des droits et libertes, mais s'est dote en contrepartie, d'une loi sur les services en francais. En Ontario habite le plus grand nombre de francophones hors Quebec. Cependant, dans la negociation et le lobbying politique qui menerent a l'adoption de la Loi 8 sur les services en francais, la representation numerique de la population franco-ontarienne ne constitua pas un enjeu. Les Franco-Ontariens se savaient minoritaires et l'acceptaient. Ce qu'ils recherchaient en fait, etait une protection de leurs droits linguistiques a titre de minorite francophone vis-a-vis la majorite de la population d'expression anglophone. L'origine de la Loi 8 remonte jusqu'aux gouvernements conservateurs de J. Robarts et de W. Davis. Ces deux Premiers ministres ontariens furent les precurseurs politiques provinciaux dans la creation et l'etablissement d'une politique linguistique en faveur de l'epanouissement de la minorite franco-ontarienne. Cependant, leur vue des choses compartimentait les secteurs des services offerts a la population francophone et tentait de les limiter a l'education et au domaine juridique. Le nouveau gouvernement liberal de D. Peterson, en 1986, vint offrir un projet de loi sur les services en francais, la Loi 8, qui fut implantee graduellement sur une periode de trois annees. (Abstract shortened by UMI.)
First Measurement of InclusiveB →X sηDecays
Creators: name: Nishimura, K.
name: Browder, T. E.
name: Adachi, I.
name: Aihara, H.
name: Arinstein, K.
name: Aushev, T.
name: Bakich, A. M.
name: Balagura, V.
name: Barberio, E.
name: Belous, K.
name: Bhardwaj, V.
name: Bischofberger, M.
name: Bondar, A.
name: Bozek, A.
name: Bračko, M.
name: Chang, M.-C.
name: Chao, Y.
name: Chen, A.
name: Chen, K.-F.
name: Chen, P.
name: Cheon, B. G.
name: Chiang, C.-C.
name: Cho, I.-S.
name: Choi, Y.
name: Dalseno, J.
name: Danilov, M.
name: Doležal, Z.
name: Drutskoy, A.
name: Eidelman, S.
name: Gabyshev, N.
name: Golob, B.
name: Ha, H.
name: Haba, J.
name: Hara, T.
name: Hayasaka, K.
name: Hayashii, H.
name: Horii, Y.
name: Hoshi, Y.
name: Hou, W.-S.
name: Hyun, H. J.
name: Iijima, T.
name: Inami, K.
name: Itoh, R.
name: Iwabuchi, M.
name: Iwasaki, Y.
name: Joshi, N. J.
name: Julius, T'Mir
name: Kang, J. H.
name: Kapusta, P.
name: Kawai, H.
name: Kawasaki, T.
name: Kichimi, H.
name: Kiesling, C.
name: Kim, H. J.
name: Kim, H. O.
name: Kim, M. J.
name: Kim, Y. J.
name: Kinoshita, K.
name: Ko, B. R.
name: Kodyš, P.
name: Korpar, S.
name: Križan, P.
name: Kumita, T.
name: Kuzmin, A.
name: Kwon, Y.-J.
name: Kyeong, S.-H.
name: Lange, J. S.
name: Lee, M. J.
name: Lee, S.-H.
name: Li, J.
name: Liu, C.
name: Liu, Y.
name: Liventsev, D.
name: Louvot, R.
name: Matyja, A.
name: McOnie, S.
name: Miyabayashi, K.
name: Miyata, H.
name: Miyazaki, Y.
name: Mohanty, G. B.
name: Mori, T.
name: Nakano, E.
name: Nakao, M.
name: Nakazawa, H.
name: Natkaniec, Z.
name: Nishida, S.
name: Ogawa, S.
name: Ohshima, T.
name: Olsen, S. L.
name: Ostrowicz, W.
name: Pakhlova, G.
name: Park, C. W.
name: Park, H.
name: Park, H. K.
name: Park, K. S.
name: Pestotnik, R.
name: Petrič, M.
name: Piilonen, L. E.
name: Röhrken, M.
name: Ryu, S.
name: Sahoo, H.
name: Sakai, Y.
name: Schneider, O.
name: Schwanda, C.
name: Schwartz, A. J.
name: Senyo, K.
name: Seon, O.
name: Sevior, M. E.
name: Shapkin, M.
name: Shen, C. P.
name: Shiu, J.-G.
name: Simon, F.
name: Smerkol, P.
name: Sokolov, A.
name: Solovieva, E.
name: Starič, M.
name: Sumiyoshi, T.
name: Suzuki, S.
name: Teramoto, Y.
name: Trabelsi, K.
name: Uehara, S.
name: Uglov, T.
name: Unno, Y.
name: Uno, S.
name: Varner, G.
name: Varvell, K. E.
name: Vervink, K.
name: Wang, C. H.
name: Wang, M.-Z.
name: Wang, P.
name: Watanabe, Y.
name: Wicht, J.
name: Williams, K. M.
name: Won, E.
name: Yamashita, Y.
name: Yamauchi, M.
name: Zhang, C. C.
name: Zhang, Z. P.
name: Zhou, P.
name: Zhulanov, V.
name: Zivko, T.
name: Zupanc, A.
name: Zyukova, O.
Publisher: name: Swinburne
Year: 2024

description: We report a first measurement of inclusive B→Xsη decays, where Xs is a charmless state with unit strangeness. The measurement is based on a pseudoinclusive reconstruction technique and uses a sample of 657×106BB̄ pairs accumulated with the Belle detector at the KEKB e⊃+e⊃- collider. For MXs<2.6GeV/c2, we measure a branching fraction of [26.1±3.0(stat)-2.1+1.9(syst)-7.1+4. 0(model)]×10-5 and a direct CP asymmetry of AC P=-0.13±0.04-0.03+0.02. Over half of the signal occurs in the range MXs>1.8GeV/c2.
Characterization of littoral fish assemblages and their habitat in the St. Lawrence River near Cornwall, Ontario.
Creators: name: Ribey, Sandra Carolyn.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Biology, Ecology.

description: This project was aimed at (i) characterizing and comparing littoral fish communities upstream and downstream of the Moses-Saunders hydroelectric dam on the St. Lawrence River near Cornwall, Ontario and Massena, New York and (ii) exploring relationships between habitat characteristics (including depth gradient--the distance from shore to a 1m depth, percent aquatic vegetation, and percent substrate type) and fish community characteristics (diversity, abundance and biomass). A total of 74,419 fish (43 species) were captured in 36 sites (14 upstream and 22 downstream) using a standard sampling protocol in 1994 and 1995. The downstream region (western portion of Lake St. Francis) had significantly higher number of fish species and biomass when compared to the upstream reservoir (Lake St. Lawrence). A clustering analysis of a Jaccard similarity matrix based on the presence-absence of species for each site revealed largely distinct interregional fish community composition with relatively homogeneous intra-regional communities. A principal component analysis (PCA) of fish species caught in 60% or more of sites allowed the definition of the main fish assemblages. The downstream fish community was characterized by a high abundance of Notropis volucellus, Fundulus diaphanus and Notemigonus crysoleucas, where as upstream a high abundance of Pimephales notatus was found. A PCA of habitat variables revealed a dispersal of downstream sites throughout the graph. The upstream sites clustered together. This suggests a broad spectrum of habitat types downstream, while upstream is more homogeneous. Regression and correlation analyses found relationships between fish variables and habitat variables. The downstream area had a wider variety of habitat types, as well as the higher percentage of vegetation cover, boulder and gravel, which supported a more diverse and abundant fish community.
Too many cooks- have we got our regulatory structures right?
Creators: name: Eason, Ros
Publisher: name: Swinburne
Year: 2024

description: The liberalisation of Australian telecommunications in 1997 was accompanied by changes which saw responsibility for competition policy, and especially access issues, transferred from the industry specific regulator to the ACCC. Ros Eason considers how well the current dispersal of regulatory responsibilities and energies has served the industry and asks whether it is time for a re-think of our institutional arrangements.
A real-time audio transcoder with watermark images for content protection and quality of service monitoring
Creators: name: Jabbour, Hani
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Engineering, Electronics and Electrical.

description: Audio streaming has become a popular application on the Internet over the past few years, and is expected to grow with the advent of high-speed Internet access. Content adaptability, copyright protection, and Quality of Service (QoS) monitoring of these streams are some of the major issues encountered in audio streaming. In this research study, we present a universal media access-compliant (UMA) transcoding module along with a watermarking-based data-hiding module that provides copyright protection as well as data integrity, authenticity assurance, and QoS monitoring. The audio was first adapted to multiple clients' needs on the server side, watermarked, and then sent to the connected clients. The content adaptability was done by down sampling and a sample size reduction of the live microphone-captured audio. The adaptation was done in conformance to the UMA paradigm. The watermarking, on the other hand, was done on different levels in order to provide guaranteed reliability and authenticity of the audio data as well as an efficient lightweight quality of service monitoring. The watermarking scheme was done on three different levels: First, the private watermark was watermarked by a public watermark. Second, the audio was watermarked by the watermarked private watermark using a private key. Third, the watermarked audio was watermarked again by a hashed value or itself using the same private key. The audio contains an image along with encryption and another image protecting it from temperament and allowing users to track the quality of the audio. The client would have the ability to extract the private watermark and the hash value with his private key, check the integrity of the audio using this hash value and the received audio, extract the public watermark from the private watermark, and compare it to its supposed value in order to obtain a broad idea of the quality of the service. The watermarking techniques used throughout this research were least significant bit (LSB) embedding and some variations of this technique. All the audio data that is outputted can be played with legacy audio players. The content adaptation and the watermarking will not change in any way the conformance of the audio to legacy standards.
Untersuchungsverfahren von Mikroplastikgehalten im Wasser für Praxis und Wissenschaft
Creators: name: Altmann, Korinna
name: Braun, Ulrike
name: Heller, Claudia
Publisher: name: My University
Year: 2021
Subjects: Abwasseranlage
Desorption
Gaschromatografie
Mikroplastikpartikel
Oberflächengewässer
Partikel

description: Zielsetzung des vom Bundesministerium für Bildung und Forschung geförderten Projektes RUSEKU (Repräsentative Untersuchungsstrategien für ein integratives Systemverständnis von spezifischen Einträgen von Kunststoffen in die Umwelt) war es, repräsentative Untersuchungsstrategien für die Detektion von Mikroplastik mittels TED GC/MS in wässerigen Medien zu ermitteln. Dabei wurden verschiedene Probenahmekonzepte und -verfahren für unterschiedliche Fallgestaltungen und Fragestellungen untersucht, sowie neue Filtersysteme entwickelt. Bei der Detektion der Partikel lag der Fokus auf der Anwendung und Weiterentwicklung der ThermoExtraktion/Desorption-Gaschromatographie-Massenspektrometrie (TED-GC/MS) zur Bestimmung von Mikroplastikgehalten. Anwendung fanden die Methoden bei der Beprobung von Flaschenwasser, Waschmaschinenabläufen, dem urbanen Abwassersystem der Stadt Kaiserslautern, sowie in Oberflächengewässern. © Authors