cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Biological insights into the parasitic nematode Heligmosomoides bakeri from bulk and single-cell transcriptomics
Creators: name: Pollo, Stephen Michael Jerome
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Parasitology

description: Heligmosomoides bakeri, a parasitic nematode (roundworm) of mice, is closely related to economically important parasites of livestock and the hookworm parasites of humans. As a murine parasite it is more amenable to being maintained and manipulated in a controlled laboratory environment than its relatives. The worm enters its host during its third larval stage and develops through another larval stage into adults that reside in the lumen of the small intestine to mate and lay their eggs. Unravelling these processes and other processes critical to H. bakeri survival could reveal new targets to use for drug discovery for controlling this group of parasites as well as refine previous predictions of immunomodulatory molecules, which have therapeutic potential. My thesis aims to describe the gene expression of H. bakeri during the parasitic phase of its lifecycle. I first used RNA sequencing to investigate how the (whole worm) expression of genes varies across the parasite’s infection. Using differential gene expression analyses I identified genes important for development and genes important for the males vs the females. I also uncovered evidence of an increased importance for anaerobic respiration in the adults compared to the larvae and hypothesize that aerobic conditions are important for the critical developmental processes of molting and cuticle synthesis. I then analyzed single-cell RNA-seq data from young adult male and female worms. Leveraging cell type markers from the model nematode C. elegans allowed me to putatively identify gamete, embryo, intestine, hypodermis, neuron, and muscle cells. The resulting cluster expression profiles can guide investigations into tissue-specific aspects of the adult worms. Putative intestinal transcription profiles suggest compartmentalization of function along the anterior-posterior axis of the worms, with an emphasis on protein synthesis in the anterior portion, as has been observed in other worms. Embryonic profiles are noticeably different from C. elegans embryogenesis, particularly with respect to paternal contributions to the early embryo. Overall, these datasets extend our understanding of how H. bakeri lives as a parasite and provide a public resource for further investigation into genes of interest. They also lay the groundwork for more comprehensive comparisons among the phylum Nematoda.
Clubiona huiming Wang, Zhang F & Zhang ZS 2018, sp. nov.
Creators: name: Wang, Luyu
name: Chen, Huiming
name: Wu, Panlong
name: Zhang, Feng
name: Zhang, Zhisheng
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Clubionidae
Clubiona
Clubiona huiming

description: Clubiona huiming Wang, Zhang & Zhang, sp. nov. (Figs 8A–B, 9A–C) Material examined. Holotype ♂, China, Guizhou, Fanjing Mountain Reserve, Mianxuling (27°54.54′N, 108°39.83′E; elev. 1974 m), 30.IX.2013, L.Y. Wang, D. Wang & X.K. Jiang leg. Paratype. 1♂, between Jinding and Jiandaoxia, 13.X.2014, C. Jin & Z.Z. Gao leg. Etymology. The specific name honours Dr. Huiming Chen, a researcher on biospeleology and local animal resource of Guizhou, China; noun. Diagnosis. Males of the new species are similar to C. subapplanata Wang, Chen & Zhang ZS, sp. nov. (Figs 14A–B, 15A, C–F), but differs from the latter by the VTA as long as wide, the long and slender embolus and the tapering and coiled conductor (Figs 8A–B, 9B–C) (VTA wider than long, embolus short and conductor reduced in C. subapplanata Wang, Chen & Zhang ZS, sp. nov.). Description. Male (Fig. 9A). Holotype total length 4.16. Carapace 2.10 long, 1.58 wide; abdomen 2.07 long, 1.27 wide. Carapace yellowish brown. Eye sizes and interdistances: AME 0.08, ALE 0.14, PME 0.12, PLE 0.14; AME–AME 0.07, AME–ALE 0.04, PME–PME 0.17, PME–PLE 0.10, ALE–PLE 0.05. MOA 0.31 long, front width 0.25, back width 0.40. Clypeus height 0.07. Chelicerae yellow brown, with 5 promarginal and 5 retromarginal teeth. Pairs of ventral spines: Tibia I 3; Metatarsus I 1; Tibia II 3; Metatarsus II 1. Leg measurements: I 4.92 (1.42, 1.98, 0.96, 0.56); II 5.35 (1.61, 2.13, 1.01, 0.60); III 4.57 (1.34, 1.62, 1.11, 0.50); IV 6.58 (1.96, 2.09, 1.94, 0.59). Leg formula 4213. Abdomen yellowish brown. Male pedipalp (Figs 8A–B, 9B–C). Femur without apophysis. Patella longer than wide. Tibia shorter than patella, with 3 apophyses. RTA almost conical, located distally. VTA almost as long as wide. LTA wide and short, located proximally. Embolus long and coiled, arising distally from tegulum. Conductor wide in mid-part and tapering toward its apex. Sperm duct U-shaped. Female. Unknown. Distribution. Known only from the type locality, Guizhou, China. Comment. The new species belongs to the C. corticalis -group.
description: Published as part of Wang, Luyu, Chen, Huiming, Wu, Panlong, Zhang, Feng & Zhang, Zhisheng, 2018, Spider diversity in Fanjing Mountain Nature Reserve, Guizhou, China, II: Clubionidae (Araneae), pp. 317-333 in Zoological Systematics 43 (3) on pages 324-325, DOI: 10.11865/zs.201827, http://zenodo.org/record/5366468
Additional file 4 of Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis
Creators: name: Kuttanamkuzhi, Abhijith
name: Panda, Debiprasad
name: Malaviya, Radhika
name: Gaidhani, Gautami
name: Lahiri, Mayurika
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 4.
Additional file 5 of Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis
Creators: name: Kuttanamkuzhi, Abhijith
name: Panda, Debiprasad
name: Malaviya, Radhika
name: Gaidhani, Gautami
name: Lahiri, Mayurika
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 5.
Correlated Quantum Transport of Density Wave Electrons
Creators: name: Miller, J. H.
name: Wijesinghe, A. I.
name: Tang, Z.
name: Guloy, A. M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Recently observed Aharonov-Bohm quantum interference of period h/2e in charge density wave rings strongly suggest that correlated density wave electron transport is a cooperative quantum phenomenon. The picture discussed here posits that quantum solitons nucleate and transport current above a Coulomb blockade threshold field. We propose a field-dependent tunneling matrix element and use the Schrodinger equation, viewed as an emergent classical equation as in Feynman's treatment of Josephson tunneling, to compute the evolving macrostate amplitudes, finding excellent quantitative agreement with voltage oscillations and current-voltage characteristics in NbSe3. A proposed phase diagram shows the conditions favoring soliton nucleation versus classical depinning. (Published in Phys. Rev. Lett. 108, 036404 (2012).)
description: 9 pages, 4 figures, (5 pages & 3 figures for main article), includes Supplemental Material with 1 figure. Published version: Physical Review Letters, vol. 108, p. 036404 (2012)
Characterization of Livestock Production Systems and the Potential of Feed-based Interventions for Improving Livestock Productivity in Konoin Division Bomet County (Kenya)
Creators: name: Wafula, Sylvia
name: Kirui, Josephine
name: Lukuyu, Ben
Publisher: name: Gates Open Research
Year: 2019

description: Characterization of Livestock Production Systems and the Potential of Feed-based Interventions for Improving Livestock Productivity in Konoin Division Bomet County (Kenya)
Additional file 2 of Glycemic control and neonatal outcomes in women with gestational diabetes mellitus treated using glyburide, metformin, or insulin: a pairwise and network meta-analysis
Creators: name: Yu, Dan-Qing
name: Xu, Guan-Xin
name: Teng, Xin-Yuan
name: Xu, Jing-Wei
name: Tang, Liang-Fang
name: Feng, Chun
name: Rao, Jin-Peng
name: Jin, Min
name: Wang, Li-Quan
Publisher: name: figshare
Year: 2021
Subjects: Biochemistry
Medicine
Biotechnology
Chemical Sciences not elsewhere classified

description: Additional file 2: Supplementary Fig. 1. Flow chart of study selection.
Experimental Observation of Energy Modulation in Electron Beams Passing Through Terahertz Dielectric Wakefield Structures
Creators: name: Antipov, S.
name: Jing, C.
name: Fedurin, M.
name: Gai, W.
name: Kanareykin, A.
name: Kusche, K.
name: Schoessow, P.
name: Yakimenko, V.
name: Zholents, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We report observation of a strong wakefield induced energy modulation in an energy-chirped electron bunch passing through a dielectric-lined waveguide. This modulation can be effectively converted into a spatial modulation forming micro-bunches with a periodicity of 0.5 - 1 picosecond, hence capable of driving coherent THz radiation. The experimental results agree well with theoretical predictions.
description: v3. Reviewers' suggestions incorporated. Accepted by PRL
Development of 3D MOF Nanocomposites with Semiconducting Behavior for Resistive Gas Sensors and Photodetectors Applications
Creators: name: Himayoonnia, Setareh
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Engineering

description: This thesis presents a comprehensive exploration of three distinct projects involving novel nanocomposites consisting of metal-organic frameworks (MOFs) combined with multiwall carbon nanotubes (MWCNTs) and carbon nanofibers (CNFs). These projects encompass methane (CH4) detection, the application of MOF composites for diabetes diagnosis through acetone detection, and their utilization as advanced photodetectors. In the first project, addressing the critical issue of CH4 detection, an innovative MOF/MWCNTs-based resistive sensor was developed. CH4 detection is crucial due to its environmental and safety implications. Existing detection methods often struggle with low concentrations of CH4 at room temperature (RT), typically within the range of a few parts per million (ppm). The developed sensor offers cost-efficiency, reliability, high sensitivity, and selectivity, presenting a breakthrough technology with the potential to significantly enhance environmental monitoring and industrial safety. The second project focuses on diabetes management, a global health concern. Traditional invasive blood glucose measurements can be cumbersome. To simplify and improve diabetes monitoring, the research investigates non-invasive nanomaterial-based gas sensors for detecting acetone, a diabetes biomarker. The developed MOF/MWCNTs nanocomposite resistive sensor offers selective detection of acetone at RT and atmospheric pressure, exhibiting remarkable sensitivity. The limit of detection is three orders of magnitude lower than the concentration of acetone in the exhaled breath of diabetic patients. The third project explores the application of MOF/CNF nanocomposites in photodetectors, crucial components in various technological domains. Traditional photodetectors face limitations, such as broadband absorption and the need for costly optical filters in narrowband applications. The introduced MOF/CNF nanocomposites address these challenges, combining the strengths of MOFs and CNFs while mitigating their weaknesses. This research not only overcomes limitations in traditional and recent nanomaterials-based photodetectors but also extends the capabilities of three-dimensional (3D) MOFs in narrowband photodetection applications, potentially revolutionizing photodetection technology. Overall, this thesis explores the potential of MOF-based nanocomposites in addressing critical challenges in CH4 detection, diabetes management, and photodetection, holding promise for environmental preservation, healthcare, and technological advancements.
Selective darkening of degenerate transitions for implementing quantum controlled-NOT gates
Creators: name: de Groot, P. C.
name: Ashhab, S.
name: Lupascu, A.
name: DiCarlo, L.
name: Nori, Franco
name: Harmans, C. J. P. M.
name: Mooij, J. E.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We present a theoretical analysis of the selective darkening method for implementing quantum controlled-NOT (CNOT) gates. This method, which we recently proposed and demonstrated, consists of driving two transversely-coupled quantum bits (qubits) with a driving field that is resonant with one of the two qubits. For specific relative amplitudes and phases of the driving field felt by the two qubits, one of the two transitions in the degenerate pair is darkened, or in other words, becomes forbidden by effective selection rules. At these driving conditions, the evolution of the two-qubit state realizes a CNOT gate. The gate speed is found to be limited only by the coupling energy J, which is the fundamental speed limit for any entangling gate. Numerical simulations show that at gate speeds corresponding to 0.48J and 0.07J, the gate fidelity is 99% and 99.99%, respectively, and increases further for lower gate speeds. In addition, the effect of higher-lying energy levels and weak anharmonicity is studied, as well as the scalability of the method to systems of multiple qubits. We conclude that in all these respects this method is competitive with existing schemes for creating entanglement, with the added advantages of being applicable for qubits operating at fixed frequencies (either by design or for exploitation of coherence sweet-spots) and having the simplicity of microwave-only operation.
description: 25 pages, 5 figures
Framing Policing Image and Reputation: Police Engagement with Social Media as a Tool to Employ Impression Management Tactics
Creators: name: Dewar, Adriana Lucia
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Impression Management
subject: Policing Image
subject: Reputation Maintenance
subject: Social Media
subject: Qualitative
subject: Education--Sociology of

description: Historically, policing agencies have had a great deal of control over the information released about them. Prior to social media, information was disseminated through media channels such as newspaper articles or press conferences. This allowed for the information to be carefully tailored to highlight only the positive aspects of police behaviour, which directly benefitted them. Alternatively, police used these channels to regulate the information being presented to the public to maintain the position of gatekeeper of influential information. Social media and instant technologically mediated communications offer profound novel opportunities for police to communicate with the public, but also new risks, such as, losing public confidence, legitimacy, and issues of animosity. This study utilized qualitative methods to capture how police agencies employ social media as a means to engage in impression management tactics to influence the public’s perception. In addition, the study analyzed the public’s attitudes and beliefs about the police and their views on policing as a profession through the type of interactions occurring online. The qualitative data was gathered through in-depth interviews with the communications personnel and current police officers from a police agency in Western Canada. In conjunction with the in-depth interviews, an ethnographic content analysis was performed on the social media accounts (Instagram, Twitter, and TikTok) of police agencies in Vancouver, Calgary, Edmonton, Regina, and Winnipeg. This research uncovered the impression management tactics being used to influence the public’s perception of the police. In addition, this research illuminated points of contention between the police and civilians, as well as methods for increasing positive interactions on various social networking platforms.
Persistence of Burkholderia pseudomallei, B. multivorans and B. cenocepacia : differential analysis by proteomics and activation of phosphoinositide-3 kinase
Creators: name: Velapatino Cochachi, Rossi Billie
Publisher: name: University of British Columbia
Year: 2013

description: Persistent infection in mammalian hosts is one intriguing aspect of the study of human diseases. In order to gain insight into the establishment of persistence, this thesis will evaluate the bacterial and host components associated with persistence of two groups within the Burkholderia genus: Burkholderia pseudomallei and Burkholderia cepacia complex. Burkholderia pseudomallei causes septicemic melioidosis with a high rate of relapse; however microbial determinants of relapse are unknown. Proteins were analyzed from sequential B. pseudomallei isolates from primary and relapsing melioidosis. Analysis by iTRAQ revealed that factors required for nitric oxide detoxification (HmpA) and necessary for anaerobic growth (ArcA, ArcC, and ArcB) were highly expressed in the relapse isolate. 2D-PAGE revealed up-regulation of a putative hcp-1 protein in the primary isolate, and flagellin and HSP20/alpha crystalline in the relapse isolate. These observations provide targets for further analysis of latency and virulence of B. pseudomallei in patients with relapsing melioidosis. The role of the host phosphoinositide3-kinase/Akt (PI3K/Akt) signaling pathway in the interaction of Burkholderia cepacia complex (Bcc) species with human immortalized macrophages was explored. B. cenocepacia and B. multivorans are the most clinically important and prevalent of the Bcc members and are serious opportunistic pathogens in cystic fibrosis (CF) patients. This study evaluated whether these pathogens can differentially induce PI3K/Akt signaling pathway, which is important in cell survival. B. cenocepacia activated PI3K/Akt in multiple cell types and this activation proceeded faster after exposure to B. multivorans than to B. cenocepacia in macrophages. Both species promoted cell survival by preventing caspase 9 cleavage, and bacteria internalization was necessary for this process. Unlike, B. cenocepacia, B. multivorans induced PI3K/Akt mediated anti-apoptotic effect, faster NF-κB activation, and IκBα phosphorylation that was PIK3/Akt dependent. Macrophages exposed to B. cenocepacia induced greater proinflammatory cytokines release compared to B. multivorans. Internalization into macrophages of both species was PI3K regulated. These findings provide novel insights into the pathogenic mechanism underlying Bcc infection in CF. Together; this thesis provides data for the identification of mechanisms leading to the persistence of these bacteria in melioidosis and CF and may inform the design of therapeutic approaches for treatment in these diseases.
Introduction to topological superconductivity and Majorana fermions
Creators: name: Leijnse, Martin
name: Flensberg, Karsten
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This short review article provides a pedagogical introduction to the rapidly growing research field of Majorana fermions in topological superconductors. We first discuss in some details the simplest "toy model" in which Majoranas appear, namely a one-dimensional tight-binding representation of a p-wave superconductor, introduced more than ten years ago by Kitaev. We then give a general introduction to the remarkable properties of Majorana fermions in condensed matter systems, such as their intrinsically non-local nature and exotic exchange statistics, and explain why these quasiparticles are suspected to be especially well suited for low-decoherence quantum information processing. We also discuss the experimentally promising (and perhaps already successfully realized) possibility of creating topological superconductors using semiconductors with strong spin-orbit coupling, proximity-coupled to standard s-wave superconductors and exposed to a magnetic field. The goal is to provide an introduction to the subject for experimentalists or theorists who are new to the field, focusing on the aspects which are most important for understanding the basic physics. The text should be accessible for readers with a basic understanding of quantum mechanics and second quantization, and does not require knowledge of quantum field theory or topological states of matter.
description: 21 pages, 5 figures
Capacitance-Resistance Model Connectivity Evaluation Based on Empirical and Heat Transfer Analogy Approaches in Conventional and Heavy Oil Waterfloods
Creators: name: Morales German, Gabriela
Publisher: name: Schulich School of Engineering
Year: 2023
Subjects: subject: Waterflooding
subject: Connectivity analysis
subject: Capacitance-resistance model
subject: Heavy oil reservoirs
subject: Heat transfer analogy
subject: Engineering--Petroleum

description: Inter-well connectivity (IWC) is a key factor for the successful design and operation of waterflooding projects. Thus, connectivity estimation methods such as the Capacitance-Resistance Model (CRM) are continually being improved and developed. The CRM utilizes the injection and production data as input to quantify IWC information through a connectivity parameter (λ). Proposed in 2006, the CRM has been adapted several times to better perform in challenging exploitation projects such as heavy oil waterflooding. Nonetheless, CRM analysis in heavy oil reservoirs yields highly variable λ values during early times. Such a variation and inconsistency make it difficult to readily determine IWC. This research work proposes two novel approaches to improve the CRM analysis by evaluating the uncertainty in the IWC estimates, especially at the early production stage. In the first approach, data generated from reservoir simulations provide input for the CRM to estimate IWC for each injection-production well pair. The objective is to define an equation relating production data and λ behavior patterns for different high mobility ratio cases. The proposed formulation yields acceptable IWC results in homogeneous reservoir cases and provides insight into heterogeneous reservoir evaluations. For the second approach, the analogous behavior of heat conduction and pressure transients is used to complement the CRM analysis. Previous studies suggest that, besides inter-well distance (IWD), IWC estimation might be influenced by injection rate frequency (ω_a) and medium hydraulic diffusivity (D). Sensitivities of those parameters were carried out to determine their effect on IWC. As a result, applying the periodic line source solution (PLSS) for heat conduction, ω_a, D and IWD can all be considered for IWC estimation, and their effects quantified. The PLSS analysis also offered an improvement on a previously proposed method to estimate CRM connectivity prediction errors. The modification includes the effects of ω_a and IWD to provide a better error predictor. A field-case example of the modified method shows the impact of IWD and ω_a in the deviation of CRM- λs. A relevant benefit of this method is its applicability to a wide range of reservoir conditions and fluid types, at any field development stage.
High intergrain critical current density in fine-grain (Ba0.6K0.4)Fe2As2 wires and bulks
Creators: name: Weiss, J. D.
name: Tarantini, C.
name: Jiang, J.
name: Kametani, F.
name: Polyanskii, A. A.
name: Larbalestier, D. C.
name: Hellstrom, E. E.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The K- and Co-doped BaFe2As2 (Ba-122) superconducting compounds are potentially useful for applications because they have upper critical fields (Hc2) of well over 50 T, Hc2 anisotropy Gamma < 2, and thin film critical current densities exceeding 1 MAcm-2 at 4.2 K. However, thin-film bicrystals of Co-doped Ba-122 clearly exhibit weak link behavior for [001] tilt misorientations of more than about 5 degrees, suggesting that textured substrates would be needed for applications, as in the cuprates. Here we present a contrary and very much more positive result in which untextured polycrystalline (Ba0.6K0.4)Fe2As2 bulks and round wires with high grain boundary density have transport critical current densities well over 0.1 MAcm-2 (SF, 4.2 K), more than 10 times higher than that of any other ferropnictide wire. The enhanced grain connectivity is ascribed to their much improved phase purity and to the enhanced vortex stiffness of this low-anisotropy compound (Gamma ~ 1-2) compared to YBa2Cu3O7-x (Gamma ~ 5).
description: Final version published in Nature Materials
Additional file 6 of Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis
Creators: name: Kuttanamkuzhi, Abhijith
name: Panda, Debiprasad
name: Malaviya, Radhika
name: Gaidhani, Gautami
name: Lahiri, Mayurika
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 6.
Data-driven catalyst design for electrochemical CO2 reduction reaction (CO2RR)
Creators: name: Talebi, Pooya
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Cabon dioxide reduction
subject: Electrochemistry
subject: DFT
subject: Density Functional Theory
subject: Materials design
subject: Catalysis
subject: Carbon Utilization
subject: Chemistry--Physical
subject: Environmental Sciences

description: Carbon dioxide (CO2) poses significant global problems, primarily driving climate change and environmental degradation. Fossil fuel combustion leads to rising temperatures, extreme weather events, and ocean acidification. Addressing this challenge necessitates international cooperation, transitioning to renewable energy sources, and implementing policies to reduce emissions and the CO2content in the atmosphere. Electrochemical CO2 reduction (CO2RR) is a promising strategy to mitigate CO2 emissions and combat climate change. By utilizing renewable energy sources, such as solar or wind, CO2RR employs electrocatalysts to convert carbon dioxide into valuable chemicals and fuels. This technology aims to reduce CO2 levels in the atmosphere and to develop a sustainable and circular carbon economy, offering a potential pathway to tackle the challenges posed by excess carbon dioxide and promoting a greener, more efficient future. Nevertheless, numerous technical challenges must be addressed for successful CO2RR implementation, with a primary concern being the lack of a suitable catalyst for the reaction. Presently, copper stands as the only mono-metallic electrocatalyst capable of catalyzing CO2RR, but its performance remains economically impractical. This thesis focuses on exploring and developing non-copper-based catalysts for CO2RR in an effort to overcome this limitation and advance the feasibility of the process. Chapter 3 introduces a novel approach to identify potential catalysts for CO2RR using high-throughput density functional theory (DFT) calculations. The study screened 800 transition metal nitrides (TMNs) and singled out Co, Cr, and Ti TMNs as the most promising candidates based on thermodynamic analysis, with their stability and activity thoroughly assessed. Additionally, machine learning (ML) regression models were employed to predict binding energies, uncovering that the group number of metals significantly impacts the binding energy of *OH and, consequently, the catalysts' stability. By combining high-throughput DFT screening and ML regression analysis, this study demonstrates an effective means of discovering new energy materials for CO2 reduction. In Chapters 4 and 5, metal sulfide, and oxides are investigated respectively. Using experimental validation, it is shown that the 2D SnS2 and the ABO3 perovskites discussed are promising catalyst materials for CO2RR. Furthermore, in Chapter 4, a novel strategy has been implemented to increase the efficiency of the catalyst. By applying an oscillating potential (as opposed to a static and constant potential) to the cell, the Faradaic efficiency (FE) of the cell is improved significantly.
Some geometric analysis on generic Ricci solitons
Creators: name: Mastrolia, Paolo
name: Rigoli, Marco
name: Rimoldi, Michele
Publisher: name: arXiv
Year: 2011
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C21

description: We study the geometry of complete generic Ricci solitons with the aid of some geometric-analytical tools extending techniques of the usual Riemannian setting.
description: 21 pages. Final version: to appear on Commun. Contemp. Math
Clubiona subcylindrata Wang, Chen & Zhang ZS 2018, sp. nov.
Creators: name: Wang, Luyu
name: Chen, Huiming
name: Wu, Panlong
name: Zhang, Feng
name: Zhang, Zhisheng
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Clubionidae
Clubiona
Clubiona subcylindrata

description: Clubiona subcylindrata Wang, Chen & Zhang ZS, sp. nov. (Figs 16A–C, 17A–D) Material examined. Holotype ♂, China, Guizhou, Fanjing Mountain Reserve, Heiwanhe (27°50.778′N, 108°46.362′E; elev. 533 m), 26.IX.2013, L.Y. Wang, D. Wang & X.K. Jiang leg. Etymology. The specific name is taken from its similarity to C. cylindrata Liu, Yan, Griswold & Ubick, 2007; adjective. Diagnosis. The new species is similar to C. cylindrata Liu, Yan, Griswold & Ubick, 2007 (Liu et al., 2007: 67, figs 11– 15), but differs from the latter by the RTA wider than a half of its length, much wider, membranous conductor (Figs 16A–C, 17B–D) (width of RTA less than a half of its length and slender, indistinct conductor in C. cylindrata). Description. Male (Fig. 17A). Holotype total length 8.72. Carapace 3.72 long, 2.72 wide; abdomen 5.12 long, 2.23 wide. Eye sizes and interdistances: AME 0.16, ALE 0.20, PME 0.17, PLE 0.17; AME–AME 0.17, AME–ALE 0.07, PME– PME 0.34, PME–PLE 0.24, ALE–PLE 0.12. MOA 0.50 long, front width 0.49, back width 0.67. Clypeus height 0.10. Chelicerae with 4 promarginal and 2 retromarginal teeth. Pairs of ventral spines: Tibia I 2; Metatarsus I 1; Tibia II 2; Metatarsus II 1. Leg measurements: I 10.50 (2.88, 4.16, 2.24, 1.22); II 11.74 (3.13, 4.73, 2.53, 1.35); III 9.21 (2.61, 3.33, 2.44, 0.83); IV 12.08 (3.02, 4.08, 3.78, 1.20). Leg formula 4213. Abdomen yellow brown. Male pedipalp (Figs 16A–C, 17B–D). Femur and patella without apophysas. Patella and tibia almost 2 times longer than wide. Tibia with two apophyses: RTA short, with slightly peaked apex; VTA small, slightly wider than long. Conductor membranous, wide and slightly folded. Embolus slender, arising prolaterally, extending distally. Part of sperm duct visible on disto-retrolateral side of tegulum. Female. Unknown. Distribution. Known only from the type locality, Guizhou, China. Comment. The new species belongs to the C. corticalis- group.
description: Published as part of Wang, Luyu, Chen, Huiming, Wu, Panlong, Zhang, Feng & Zhang, Zhisheng, 2018, Spider diversity in Fanjing Mountain Nature Reserve, Guizhou, China, II: Clubionidae (Araneae), pp. 317-333 in Zoological Systematics 43 (3) on pages 328-330, DOI: 10.11865/zs.201827, http://zenodo.org/record/5366468
description: {"references": ["Liu, P., Yan, H. M., Griswold, C., Ubick, D. 2007. Three new species of the genus Clubiona from China (Araneae: Clubionidae). Zootaxa, 1456: 63 - 68."]}
Utilizing Statistical and Machine Learning Techniques to Improve Tools Identifying Genetic Basis Underlying Complex Traits
Creators: name: Bian, Jiayi
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Biostatistics

description: In genetic studies, understanding the genetic basis underlying complex traits takes center stage. Modern high-throughput technologies have empowered researchers to generate large amounts of multi-scale omics data that bridge the gap between genotype and phenotype. With the availability of omics data, researchers have successfully identified genetic variants and genes underlying complex traits using genome-wide association studies (GWAS) and other association mapping methods using omics data as mediators, e.g., transcriptome-wide association studies (TWAS). To provide better statistical tools unraveling the genetic basis of complex traits, I have developed three statistical methods: AE-TWAS, edLMM, and Kernel-smoothed permutation, respectively focusing on three stages of association mapping, namely input data denoising, statistical test to detect low-effect variants, and non-parametric generation of small P-values. My first project delves into the limitations of TWAS from the perspective of transcriptomic data denoising by transformation. I introduced AE-TWAS (AutoEncoder-transformed TWAS), which incorporates autoencoder-transformed transcriptome data into a standard TWAS protocol. We showed that AE-TWAS boosts the heritability of low-heritability genes in transcriptomic data and the transformed transcriptome leads to better performance of TWAS. In my second project, I introduced edLMM (expression- directed Linear Mixed Model) that incorporates weights derived from transcriptomic data in a linear mixed model (LMM). These weights provide an alternative estimate of the null hypothesis in an LMM by re-scaling the genetic relationship matrix (GRM). Through real data analysis and simulation studies, we demonstrated that edLMM is more powerful than the benchmark LMM method in GWAS (i.e., EMMAX), especially in its capacity to enhance the identification of genetic variants with low effects. My third project focused on the challenge of accurately estimating small p-values in genetic association studies using permutations when the closed-form distribution of test statistics is unknown. Specifically, I developed Kernel-smoothed permutation, a method that constructs the null distribution of a test statistic through a novel kurtosis-driven Box-Cox transformation, followed by a kernel- based density estimation (KDE). We demonstrated that our approach requires a magnitude of lower rounds of permutations than the conventional Na ̈ıve permutation. Taking together, my thesis contributed meaningful additions to the toolbox of association mapping from three abovementioned aspects, enhancing our ability to identify the genetic basis of complex traits in the cases of low expression heritability genes, low effect-size genetic variants, and low numbers of sampled permutations. These works push the boundary of association mapping to the corners that may be missed by using conventional tools.
Theory of neutrinoless double beta decay
Creators: name: Vergados, J. D.
name: Ejiri, H.
name: Simkovic, F.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Neutrinoless double beta decay, which is a very old and yet elusive process, is reviewed. Its observation will signal that lepton number is not conserved and the neutrinos are Majorana particles. More importantly it is our best hope for determining the absolute neutrino mass scale at the level of a few tens of meV. To achieve the last goal certain hurdles have to be overcome involving particle, nuclear and experimental physics. Nuclear physics is important for extracting the useful information from the data. One must accurately evaluate the relevant nuclear matrix elements, a formidable task. To this end, we review the sophisticated nuclear structure approaches recently been developed, which give confidence that the needed nuclear matrix elements can be reliably calculated. From an experimental point of view it is challenging, since the life times are long and one has to fight against formidable backgrounds. If a signal is found, it will be a tremendous accomplishment. Then, of course, the real task is going to be the extraction of the neutrino mass from the observations. This is not trivial, since current particle models predict the presence of many mechanisms other than the neutrino mass, which may contribute or even dominate this process. We will, in particular, consider the following processes: (i)The neutrino induced, but neutrino mass independent contribution. (ii)Heavy left and/or right handed neutrino mass contributions. (iii)Intermediate scalars (doubly charged etc). (iv)Supersymmetric (SUSY) contributions. We will show that it is possible to disentangle the various mechanisms and unambiguously extract the important neutrino mass scale, if all the signatures of the reaction are searched in a sufficient number of nuclear isotopes.
description: 104 pages, 6 tables, 25 figures.References added. To appear in ROP (Reports on Progress in Physics), copyright ROP
The levels of analysis question in the cross-Strait bargain : domestic constraints and international bargaining power
Creators: name: Chen, Ted Hsuan Yun
Publisher: name: University of British Columbia
Year: 2012

description: Our understanding of the bargain between China and Taiwan depends on our ability to effectively untangle the myriad of processes that exists at multiple levels across the Taiwan Strait. By examining in this context Robert Putnam's two-level game, widely endorsed as the answer to this methodological puzzle but never rigorously examined, I seek to determine the relevant levels of analysis needed to explain, predict, and shape cross-Strait bargaining outcomes. I examine two working hypotheses and a set of supporting questions, derived from Putnam's article and related works, against empirical evidence from the most recent iteration of the cross-Strait bargain, from Ma Ying-jeou's election in 2008 to the 2012 Presidential Elections in Taiwan. On the methodological front, the empirical evidence speaks to the power of systemic-level variables, but ultimately demonstrates the necessity of incorporating domestic-level variables according to the two-level game's interactive logic in any analysis shorter than the longest of the long runs. Regarding substantive aspects of the cross-Strait bargain, my findings suggest that Beijing is most likely to succeed in manipulating the Taiwanese domestic constituency by focusing on mobilizing segments of Taiwanese society with interests similar to its, specifically through agent-specific punishment promoting the KMT at the expense of the DPP. We are presented with the situation in which the KMT is the better agent when it comes to gaining concessions from Beijing, but cannot do so unless the DPP has a credible chance to spend regular time in office.
Additional file 7 of Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis
Creators: name: Kuttanamkuzhi, Abhijith
name: Panda, Debiprasad
name: Malaviya, Radhika
name: Gaidhani, Gautami
name: Lahiri, Mayurika
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 7.
Quantum Integrability for Three-Point Functions
Creators: name: Gromov, Nikolay
name: Vieira, Pedro
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Quantum corrections to three-point functions of scalar single trace operators in planar N=4 Super-Yang-Mills theory are studied using integrability. At one loop, we find new algebraic structures that not only govern all two loop corrections to the mixing of the operators but also automatically incorporate all one loop diagrams correcting the tree level Wick contractions. Speculations about possible extensions of our construction to all loop orders are given. We also match our results with the strong coupling predictions in the classical (Frolov-Tseytlin) limit.
description: 4 pages, 3 figures
Investigating the Sexual Dimorphism of Disease Tolerance in Sepsis
Creators: name: Dobson, Breenna
Publisher: name: Graduate Studies
Year: 2023
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Sepsis is a dysregulated immune response to infection, with mortality rates as high as 30%, however, there are currently no disease-modifying treatments for this disease. One of the reasons why preclinical sepsis discoveries have failed to translate into effective human therapies is that interindividual heterogeneity has historically been neglected in preclinical sepsis research, including the fundamental contributions of biological sex on disease pathogenesis and treatment response. Epidemiologic studies have observed that males have a higher incidence, severity and mortality rate than females in sepsis, however, the mechanisms underlying this bias have not yet been established. This thesis aims to examine potential underlying mediators of the sexual dimorphism within sepsis illness severity. We investigated the impact of biological sex on host defence using a well-established mouse model of sepsis induced by fecal peritonitis. We used this model to study three principal mediators of sex- based immune response differences: the gut microbiota, sex chromosomes and sex hormones. To uncover differences in these mediators we used a transgenic and germ-free mouse model. Further, we aimed to understand the sex-based influence on infection tolerance and resistance. Lastly, we completed preliminary studies on sex-based differences in infection tolerance using a tetracycline antibiotic as a potentiator of mitochondrial tolerance. This project addressed a critical gap within sepsis research and revealed biological sex differences in infection tolerance and potential therapeutic implications.
Additional file 8 of Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis
Creators: name: Kuttanamkuzhi, Abhijith
name: Panda, Debiprasad
name: Malaviya, Radhika
name: Gaidhani, Gautami
name: Lahiri, Mayurika
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 8.
Lunatic Teacher: A Hermeneutic Exploration of Teaching and Suicide in Poetry and Prose
Creators: name: Perry, Tyler Brendan
Publisher: name: Werklund School of Education
Year: 2023
Subjects: subject: poetry
subject: hermeneutics
subject: teaching
subject: suicide
subject: creative writing
subject: teacher wellness
subject: sestina
subject: glosa
subject: T. S. Eliot
subject: Patrick Lane
subject: Albert Camus
subject: Stevie Smith
subject: English language arts
subject: Shakespeare
subject: Hamlet
subject: a/r/tography
subject: poetic inquiry
subject: Hans Georg Gadamer
subject: Paul Ricoeur
subject: The Love Song of J. Alfred Prufrock
subject: William Butler Yeats
subject: Education
subject: Education--Language and Literature
subject: Education--Philosophy of
subject: Education--Reading
subject: Education--Secondary
subject: Literature
subject: Literature--Canadian (English)
subject: Literature--English
subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: This hermeneutic exploration seeks to interpret and understand the author’s ongoing experience as a teacher, observer, and writer through the creation of lyrical poetry and prose. It is a journey through language into poetic understanding—away from the clarity of concrete knowledge and into the fog of questions and creative intuition that rise from the inherent ambiguity of creative language and metaphoric meaning. The primary poetic forms used in this text are glosa, sestina, free verse, and micro essay. The glosa and sestina poems directly and methodically engage with previously existing texts (poetry and prose) by following the patterns and rules of said forms. The free verse poems engage directly with these texts by weaving lines, phrases, and sentences among the freely written new lines in no predetermined pattern, and by rules set only during the play of writing. The micro essays serve as meta writings that further the conversation by pulling back and analysing the language processes used in all the other writings. They are the planks of reason used to build a footpath along which we might traverse the otherwise soggy substance of the poems. All of the writing is infused with the experiences of teaching and living of the author of this text. The reader is asked to read amphibiously, living equally in the liquid language of poetry and the somewhat solid ground of the prose. This thesis strives towards eccentric, expansive, and paradoxical understandings of teaching, learning, language, and lunacy.
Explicit Formulas involving q-Euler Numbers and Polynomials
Creators: name: Araci, Serkan
name: Acikgoz, Mehmet
name: Seo, Jong Jin
Publisher: name: arXiv
Year: 2012
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: In this paper, we deal with q-Euler numbers and q-Bernoulli numbers. We derive some interesting relations for q-Euler numbers and polynomials by using their generating function and derivative operator. Also, we show between the q-Euler numbers and q-Bernoulli numbers via the p-adic q-integral in the p-adic integer ring.
description: 9 pages, submitted