cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Chasing electrons : exploring the redox balance of platelet functions
Creators: name: Murphy, Desmond D.
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: The platelet redox environment consists of the blood plasma and within it the lowmolecular weight thiols glutathione and cysteine. Both glutathione and cysteine exist as independent redox couples comprising carefully controlled ratios of the reduced (GSH, Cys) and oxidised (GSSG, CySS) form of each thiol. These ratios yield a GSH/GSSG redox potential and a Cys/CySS redox potential in the plasma. Changes in the redox status of the plasma are manifested by alterations in either the glutathione or cysteine redox potential and are associated with the progression of a large number of disease states including cancer, atherosclerosis and schizophrenia. In addition, oxidative changes in either of the plasma redox potentials have been directly linked with risk factors for cardiovascular disease. The post-translational modification of critical cysteine thiol groups on proteins is linked to such alterations in both the GSH/GSSG and Cys/CySS redox potentials and occurs extracellularly and intracellularly. Platelet integrins in particular are prime targets for redox modification due to their high cysteine content. Although the role of thiol/ disulphide bond exchange in platelet activation is established the effects of a changing redox environment on platelet reactivity are unclear. The aims of this thesis therefore, are to explore the impact and consequences of such changes on platelet function. Platelet activation was significantly diminished in the presence of either reducing GSH/GSSG or Cys/CySS redox potentials. Moreover, this response was most notable when platelets were activated with collagen only. The redox modulated effects were shown to be specific to the integrin ɑ2β1, through a mechanism involving disulphide bond reduction. An analysis of the platelet integrin β subunits revealed the presence of the greatest number of potentially reactive cysteine residues within the Pi subunit when compared to the other platelet integrin beta subunit β3. Furthermore, platelet proteins were S-glutathionylated in a reducing extracellular redox environment. The findings of this thesis reveal for the first time how exquisitely sensitive collagen-induced platelet activation is to alterations in the external redox environment. This, in fact, is potentially a novel demonstration of reductive stress regulating platelet reactivity and provides a novel avenue for therapeutic intervention using physiological redox reagents or their precursors.
New Jersey water withdrawals, uses, transfers, and discharges by HUC11, 1990 to 1999: User's guide
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2006

description: This New Jersey Geological Survey (NJGS) report summarizes data on water withdrawal, use, transfer and discharge in New Jersey from 1990 through 1999 for all of New Jersey's 151 11- Digit Hydrologic Unit Code (HUC11) drainage basins. The HUC11 delineations were developed by the United States Geological Survey (USGS) and modified by the New Jersey Department of Environmental Protection (NJDEP) to meet its Geographic Information Systems (GIS) mapping requirements. The NJDEPs HUC11s range in size from 3 to 349 square miles, and average about 60 square miles. HUC11s are aggregated together to form 20 Watershed Management Areas (WMA) and these are further aggregated to form 5 Water Regions (WR) (Figure 1). Withdrawals are defined as the volume of fresh water withdrawn from ground-water or surface-water sources. Withdrawals include sources regulated under the Water Supply Management Act (N.J.S.A. 58:2- 1 et seq.), and estimates of those from private domestic wells and small, public non-community water systems. Use is defined as the volume of water actually used in the HUC11, after accounting for transfers. Use is categorized into one of eight use groups: agricultural, commercial, industrial, non-agricultural irrigation, mining, potable supply, power generation and not classified. Transfers consist of water moved between HUC11s and include fresh water (e.g. bulk transfers of potable water) and sewage (e.g. via sewer collection pipes). Discharge points and reported discharge volumes are also included
title: Analyse von Hatespeech unter Berücksichtigung der strafrechtlichen Relevanz
title: Ein Lehrprojekt aus Information Science an der Hochschule Darmstadt
titleType: Subtitle
Creators: name: Siegel, Melanie
Publisher: name: Zenodo
Year: 2024

description: Im Master-Studiengang Information Science an der Hochschule Darmstadt werden Lehrprojekte durchgeführt, die sich einerseits an Forschungsarbeiten und andererseits an gesellschaftlich relevanten Fragestellungen orientieren. Die Analyse von Hatespeech stand dabei im Zusammenhang mit den Forschungsprojekten DeTox und BoTox, die mit der Meldestelle https://hessengegenhetze.de/ als Praxispartner eng zusammenarbeiten.

https://www.dgfs2024.ruhr-uni-bochum.de/dgfs/mam/content/dgfs2024-bochum-sprache-und-einstellung-tagungsband.pdf
On the averaged Green's function of an elliptic equation with random coefficients
Creators: name: Kim, Jongchon
name: Lemm, Marius
Publisher: name: arXiv
Year: 2018
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We consider a divergence-form elliptic difference operator on the lattice $\mathbb{Z}^d$, with a coefficient matrix that is an i.i.d. perturbation of the identity matrix. Recently, Bourgain introduced novel techniques from harmonic analysis to prove the convergence of the Feshbach-Schur perturbation series related to the averaged Green's function of this model. Our main contribution is a refinement of Bourgain's approach which improves the key decay rate from $-2d+ε$ to $-3d+ε$. (The optimal decay rate is conjectured to be $-3d$.) As an application, we derive estimates on higher derivatives of the averaged Green's function which go beyond the second derivatives considered by Delmotte-Deuschel and related works.
description: 47 pages
Modeling Diffusive Dynamics in Adaptive Resolution Simulation of Liquid Water
Creators: name: Matysiak, Silvina
name: Clementi, Cecilia
name: Praprotnik, Matej
name: Kremer, Kurt
name: Site, Luigi Delle
Publisher: name: arXiv
Year: 2007
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We present a dual-resolution molecular dynamics (MD) simulation of liquid water employing a recently introduced Adaptive Resolution Scheme (AdResS). The spatially adaptive molecular resolution procedure allows for changing from a coarse-grained to an all-atom representation and vice-versa on-the-fly. In order to find the most appropriate coarse-grained water model to be employed with AdResS we first study the accuracy of different coarse-grained water models in reproducing the structural properties of the all-atom system. Typically, coarse-grained molecular models have a higher diffusion constant than the corresponding all-atom models due to the reduction in degrees of freedom (DOFs) upon coarse-graining that eliminates the fluctuating forces associated with those integrated-out molecular DOFs. Here, we introduce the methodology to obtain the same diffusional dynamics across different resolutions. We show that this approach leads to the correct description of essential thermodynamic, structural and dynamical properties of liquid water at ambient conditions.
description: 12 pages, 16 figures
The application of voxel-based methods to magnetic resonance imaging in the study of psychiatric disorder.
Creators: name: Sundram, Frederick
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: While there are a number of psychiatric disorders as classified by the major international coding systems, however, the application of modem neuroimaging methods has only been utilised on a limited basis with some disorders receiving more research attention than others. Consequently, psychiatric phenotypes that have been relatively understudied are investigated further in this thesis. These disorders correspond to psychiatric disorder in: 22ql 1 deletion syndrome, temporal lobe epilepsy, antisocial personality disorder and Asperger syndrome. Subjects with each of these diagnoses were recruited and then compared to healthy matched controls using the application of novel whole-brain voxel-based analyses to their magnetic resonance imaging data whereby white matter integrity and/or brain tissue volume was assessed in each experimental study of this thesis. In Study 1, young people with 22ql 1 deletion syndrome were found to have significant differences in both white matter microstructure and volume. Additionally, there was preliminary evidence that within 22ql 1 deletion syndrome, some regional differences in fractional anisotropy were associated with allelic variation in COMT and with schizotypy. In Study 2, while significant grey and white matter volume deficits were found in temporal lobe epilepsy with comorbid psychosis, these abnormalities encompassed not only the medial temporal lobe structures but also extended to lateral temporal and extratemporal regions whereby some of the deficits also overlapped with those found in schizophrenia. In Study 3, reduced fractional anisotropy was found in antisocial personality disorder and psychopathy in tracts of interhemispheric, posterior brain and frontal lobe networks. Additionally, fractional anisotropy deficits in the frontal lobe demonstrated a significant negative correlation with psychopathy measures. Finally, in Study 4, adults with Asperger syndrome were specifically recruited and found to not only demonstrate impairments in white matter microstructural integrity in regions relevant to social skills and behaviour but also in more widespread white matter networks.
Cost-benefit Analysis of Visualization in Virtual Environments
Creators: name: Chen, Min
name: Gaither, Kelly
name: John, Nigel W.
name: McCann, Brian
Publisher: name: arXiv
Year: 2018
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Graphics (cs.GR)
subject: FOS: Computer and information sciences

description: Visualization and virtual environments (VEs) have been two interconnected parallel strands in visual computing for decades. Some VEs have been purposely developed for visualization applications, while many visualization applications are exemplary showcases in general-purpose VEs. Because of the development and operation costs of VEs, the majority of visualization applications in practice are yet to benefit from the capacity of VEs. In this paper, we examine this perplexity from an information-theoretic perspective. Our objectives are to conduct cost-benefit analysis on typical VE systems (including augmented and mixed reality, theatre-based systems, and large powerwalls), to explain why some visualization applications benefit more from VEs than others, and to sketch out pathways for the future development of visualization applications in VEs. We support our theoretical propositions and analysis using theories and discoveries in the literature of cognitive sciences and the practical evidence reported in the literatures of visualization and VEs.
description: Submitted to SciVis 2017 on 31 March 2017 and was not accepted. Authors' feedback about the SciVis 2017 reviews can be found in the cover letter accompanying the EuroVis submission. Revised with a major extension and submitted to EuroVis 2018 on 13 December 2017, but was not accepted
Discovery and characterization of tyrosinases from sea anemone pedal disc
Creators: name: Wang, Lulu
name: Teng, Luyao
name: Zhang, Xiaokang
name: Liu, Xiaohua
name: Lyu, Qianqian
name: Yang, Yan
name: Liu, Weizhi
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The formation of underwater adhesion is a complicated physiological process and many different types of enzymes are found to be essential apart from structural proteins. Previous studies have shown that various tyrosinases were present in marine adhesives, but little information is available about the over-expression and enzymatic characterization of these enzymes. Specifically, this study first identified four significantly up-regulated tyrosinases in the pedal disc of Haliplanella luciae by means of multi-omics technology, and made preliminary bioinformatics predictions. Sequence alignment showed that the Tyr1_Hl contained six conserved His residues that bind to copper ions, of which a tyrosinase with diphenolase activity named as Tyr1_HlΔ, was expressed in Escherichia coli BL21 (DE3) cells and purified by affinity chromatography. Enzymatic characterization showed that the activity of Tyr1_HlΔ was Cu2+ dependent and maximum catalytic activities were in 20 mM Tris–HCl (pH 8.0) at 37 °C. In summary, we identified novel tyrosinases in the pedal disks of sea anemone for the first time and the Tyr1_HlΔ was successfully recombinant expressed. Our study will provide basis for future exploration of bio-adhesion mechanism and design of bio-adhesives derived from sea anemones.
Impact of resting heart rate at 30 days following transcatheter or surgical aortic valve replacement and cardiovascular outcomes: insights from the PARTNER 2 trial
Creators: name: Macedo, Leon G.R.
name: Kosmidou, Ioanna
name: MA Aaron Crowley
name: MS, Maria Alu
name: Praz, Fabien
name: Chen, Shmuel
name: Nazif, Tamim
name: Babaliaros, Vasilis
name: Herrmann, Howard C.
name: Kapadia, Samir
name: Makkar, Raj
name: Webb, John
name: Thourani, Vinod H.
name: Leon, Martin B.
name: Susheel Kodali MD
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: 60506 Virology
subject: FOS: Biological sciences

description: BACKGROUND: Elevated resting heart rate (RHR) is associated with adverse cardiovascular outcomes in patients with untreated aortic valve stenosis (AS). However, the impact of RHR following transcatheter (TAVR) or surgical aortic valve replacement (SAVR) on cardiovascular outcomes is unknown. We therefore sought to determine the effect of RHR at 30 days after aortic valve replacement (AVR) on 2-year outcomes in patients with severe symptomatic AS. METHODS: The study population consists of 3,170 patients from the PARTNER 2 Trial and its embedded registries who underwent TAVR or SAVR for severe AS, and had available 12-lead electrocardiograms demonstrating sinus rhythm at 30 days post-procedure. Outcomes at 2 years were analyzed according to 30-day RHR modeled as a continuous variable and in groups (RHR ≥75 bpm and RHR <75 bpm). RESULTS: By multivariable analysis, RHR ≥75 bpm at 30 days after AVR was an independent predictor of the composite endpoint of all-cause death, rehospitalization or stroke (hazard ratio [HR] 1.26, 95% confidence interval [CI], 1.05–1.52, p = 0.015) and rehospitalization (HR 1.42, 95% CI, 1.12–1.79, p = 0.004). Similarly, RHR modeled as a continuous variable (per 5 bpm) remained an independent predictor of all-cause death, rehospitalization or stroke (adjusted HR 1.07, 95% CI, 1.03–1.11, p = 0.0007), and rehospitalization (adjusted HR 1.09, 95% CI, 1.04–1.14, p = 0.0003) at 2 years. CONCLUSIONS: In patients with severe AS treated with TAVR or SAVR, resting heart rate at 30 days post-procedure was an independent predictor of the composite endpoint of all-cause death, rehospitalization or any stroke, and of rehospitalization at 2 years.
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0393
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0393, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0393, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Electric Charge Quantization
Creators: name: Foot, R.
name: Lew, H.
name: Volkas, R. R.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Experimentally it has been known for a long time that the electric charges of the observed particles appear to be quantized. An approach to understanding electric charge quantization that can be used for gauge theories with explicit $U(1)$ factors -- such as the standard model and its variants -- is pedagogically reviewed and discussed in this article. This approach uses the allowed invariances of the Lagrangian and their associated anomaly cancellation equations. We demonstrate that charge may be de-quantized in the three-generation standard model with massless neutrinos, because differences in family-lepton--numbers are anomaly-free. We also review the relevant experimental limits. Our approach to charge quantization suggests that the minimal standard model should be extended so that family-lepton--number differences are explicitly broken. We briefly discuss some candidate extensions (e.g. the minimal standard model augmented by Majorana right-handed neutrinos).
description: 18 pages, LaTeX, UM-P-92/52
title: UMass ADVANCE Faculty Survey Report: STEM Faculty Experiences by Gender and Rank
Creators: name: Mickey, Ethel L.
Publisher: name: University of Massachusetts Amherst
Year: 2020

description: The UMass ADVANCE program is working to ensure greater equity among faculty through the power of collaboration. In this research brief, we describe some of the key findings from our initial survey, conducted in 2018-19. We will conduct the same survey in 2022-23 to measure the impact of our interventions. In this research brief, we focus on patterns among STEM faculty by rank and gender.
Liouville Black Holes
Creators: name: Mann, R. B.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The dynamics of Liouville fields coupled to gravity are investigated by applying the principle of general covariance to the Liouville action in the context of a particular form of two-dimensional dilaton gravity. The resultant field equations form a closed system for the Liouville/gravity interaction. A large class of asymptotically flat solutions to the field equations is obtained, many of which can be interpreted as black hole solutions. The temperature of such black holes is proportional to their mass-parameters. An exact solution to the back reaction problem is obtained to one-loop order, both for conformally coupled matter fields and for the quantized metric/Liouville system. Quantum effects are shown to map the space of classical solutions into one another. A scenario for the end-point of black-hole radiation is discussed.
description: 32 pgs., WATPHYS-TH93/03 (Latex plus two postscript figures appended)
Profiling microRNA in Primary Sjögren’s Syndrome: A quantitative and qualitative analysis of an Irish cohort
Creators: name: Qistina S. Pilson
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Sjögren’s syndrome (SS) is a systemic autoimmune disorder characterized by lymphocytic infiltration into exocrine glands. While dry eyes and mouth are the most common presentation, immune complex deposition may lead to systemic manifestations.In SS related DED (SSUDED), a combination of reduced aqueous tear production as a result of lacrimal gland destruction and increased tear osmolarity leads to inflammatory damage at the ocular surface. microRNAs (miR) are known to alter the expression of inflammatory cytokines, which play an important role in the pathogenesis and progression of SS. The main aim of this study was to identify miRs that potentially contribute to primary SS (pSS) in a case control study. In addition, a comprehensive assessment of DED signs, SS disease indices and quality of life (QOL) in SS was undertaken. Twenty pSS patients satisfying the AmericanUEuropean Consensus Group classification criteria (AECG) were recruited to this study. Age and sex matched healthy controls (HC) were evaluated for comparison. Prior to commencing profiling studies impression cytology (IC) was evaluated and optimised as a means of isolating miR and mRNA from primary conjunctival epithelial cells (CEC). Subsequently mRNA isolated from CEC of pSS and HC were sent for miR and mRNA microarray screening. These studies identified a panel of miRs and mRNAs with differential expression in pSS patients compared to HC. Bioinformatic analysis predicted two promising potential interactions; 1 ) Pellino3 (PELI3), a known negative regulator of type I interferon with miRU-744-U5p and 2) Early Growth Factor 1 (EGR1), a gene previously linked in SS studies with miRU3613U3p. Validation studies demonstrated significantly different expression patterns of these miRs and genes in patients compared to HC, indicating that they may potentially contribute to disease pathogenesis. Supporting this experiments using miR mimics, antagomiR and luciferase reporter assays confirmed that PELI3 is a direct target of miRU-744-U5p. Clinical and disease indices assessment gave an insight on pSS in an Irish cohort. We also confirmed the benefit of utilising both vision related QOL and global QOL XIX assessments to investigate functional status and well being of SSUDED. Overall we have identified novel miRs and targets from CECs that may become a potential biomarker for diagnosis and therapeutic target for pSS disease.
Astrochemical evolution along star formation: Overview of the IRAM Large Program ASAI
Creators: name: Lefloch, B.
name: Bachiller, R.
name: Ceccarelli, C.
name: Cernicharo, J.
name: Codella, C.
name: Fuente, A.
name: Kahane, C.
name: López-Sepulcre, A.
name: Tafalla, M.
name: Vastel, C.
name: Caux, E.
name: González-García, M.
name: Bianchi, E.
name: Gómez-Ruiz, A.
name: Holdship, J.
name: Mendoza, E.
name: Ospina-Zamudio, J.
name: Podio, L.
name: Quénard, D.
name: Roueff, E.
name: Sakai, N.
name: Viti, S.
name: Yamamoto, S.
name: Yoshida, K.
name: Favre, C.
name: Monfredini, T.
name: Quitián-Lara, H. M.
name: Marcelino, N.
name: Boechat-Roberty, H. M.
name: Cabrit, S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Evidence is mounting that the small bodies of our Solar System, such as comets and asteroids, have at least partially inherited their chemical composition from the first phases of the Solar System formation. It then appears that the molecular complexity of these small bodies is most likely related to the earliest stages of star formation. It is therefore important to characterize and to understand how the chemical evolution changes with solar-type protostellar evolution. We present here the Large Program "Astrochemical Surveys At IRAM" (ASAI). Its goal is to carry out unbiased millimeter line surveys between 80 and 272 GHz of a sample of ten template sources, which fully cover the first stages of the formation process of solar-type stars, from prestellar cores to the late protostellar phase. In this article, we present an overview of the surveys and results obtained from the analysis of the 3 mm band observations. The number of detected main isotopic species barely varies with the evolutionary stage and is found to be very similar to that of massive star-forming regions. The molecular content in O- and C- bearing species allows us to define two chemical classes of envelopes, whose composition is dominated by either a) a rich content in O-rich complex organic molecules, associated with hot corino sources, or b) a rich content in hydrocarbons, typical of Warm Carbon Chain Chemistry sources. Overall, a high chemical richness is found to be present already in the initial phases of solar-type star formation.
description: 19 pages, 7 figures, 5 Tables
Evaluation of API Request Bundling and its Impact on Performance of Microservice Architectures: artifacts, analysis figures and dataset
Creators: name: El Malki, Amine
name: Zdun, Uwe
Publisher: name: Zenodo
Year: 2021

description: The current repository describes the three main components of the empirical study conducted in the paper: Evaluation of API Request Bundling and its Impact on Performance of Microservice Architectures. Abstract of the paper: The widespread adoption of Microservice architectures has posed many challenges regarding API design for these architectures. Several API best practices and patterns have been proposed that could help API designers ensure API quality attributes such as reliability, availability, and performance. API Request Bundling, which is in focus of this paper, is one of those patterns that aims at optimizing performance. The pattern promises substantial performance gains, but can also lead to significant drawbacks such as increased development effort and application complexity. So far, there is little to no rigorously acquired knowledge to judge whether applying Request Bundling is worth the costs in a given Microservice architecture. To improve this situation, we performed an empirical study based on a Microservice-based open source business application using realistic workload scenarios. To estimate the performance impact of Request Bundling, we derived a regression model and performed a multivariate regression analysis. These selected regression models can help distributed system engineers and architects to estimate the gain in performance, in terms of round-trip time, with or without Request Bundling. Our approach followed in the paper, can be customized to other Microservice architectures or to study other performance-related Microservice patterns.
Low plasma renin activity is an independent predictor of near-term incidence of hypertension in Asian populations
Creators: name: Choo, Eun Ho
name: Ha, Kyoung Hwa
name: Seung-Won Lee
name: Kim, Hyeon Chang
name: Sungha Park
name: Lee, Hae Young
name: Sang-Hyun Ihm
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Hematology
subject: Computational Biology

description: Background: Plasma renin activity is involved in the regulation of body salt content and blood pressure. However, there is a paucity of data regarding the association between low or high plasma renin activity and the development of hypertension. Method: We investigated the relation of baseline plasma renin activity to increases in blood pressure and the incidence of hypertension after four years in 2,146 non-hypertensive individuals from a community-based Korean population (mean age, 50 years), 58% of whom were women. We defined an “increase in blood pressure” as an increment of systolic blood-pressure ≥ 10 mmHg or initiation of antihypertensive drugs and defined “hypertension” as a systolic blood pressure of 140 mm Hg or higher, a diastolic blood pressure of 90 mm Hg or higher, or the use of antihypertensive medications. Results: After 4 years, the increase in blood pressure had increased in 27.9% of the participants, and hypertension had developed in 17.9%. After adjustment, the lowest sex-specific tertile of plasma renin activity was an independent risk factor of an elevation in blood pressure (Adjusted Odds Ratio 1.37, 95% confidence interval 1.07–1.74, p = 0.011) and hypertension (Adjusted Odds Ratio 1.84, 95% confidence interval 1.36–2.50, p < 0.001) compared to the highest sex-specific tertile. The associations between the plasma renin activity and blood-pressure outcomes were evident in adults with especially high urine sodium excretion. Conclusion: Low plasma renin activity was associated with the development of hypertension in the middle-aged Asian population, especially in peoples with high sodium intake.
Synthetic Gauge Fields for Lattices with Multi-Orbital Unit Cells: Routes towards a $π$-flux Dice Lattice with Flat Bands
Creators: name: Möller, Gunnar
name: Cooper, Nigel R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a general strategy for generating synthetic magnetic fields in complex lattices with non-trivial connectivity based on light-matter coupling in cold atomic gases. Our approach starts from an underlying optical flux lattice in which flux arises by coupling several internal states. Starting from a high symmetry optical flux lattice, we superpose a scalar potential with a super- or sublattice period in order to eliminate links between the original lattice sites. As an alternative to changing connectivity, the approach can also be used to create or remove lattice sites from the underlying parent lattice. To demonstrate our concept, we consider the dice lattice geometry as an explicit example, and construct a dice lattice with a flux density of half a flux quantum per plaquette, providing a pathway to flat bands with a large band gap. While the intuition for our proposal stems from analysis of deep optical lattices, we demonstrate that the approach is robust even for shallow optical flux lattices far from the tight-binding limit. We also provide an alternative experimental proposal to realize a synthetic gauge field in a fully frustrated dice lattice based on laser-induced hoppings along individual bonds of the lattice, again involving a superlattice potential. In this approach, atoms with a long-lived excited state are trapped using an 'anti-magic' wavelength of light, allowing the desired complex hopping elements to be induced in a specific laser coupling scheme for the dice lattice geometry. We conclude by comparing the complexity of these alternative approaches, and advocate that complex optical flux lattices provide the more elegant and easily generalisable strategy.
description: 24 pages, 9 figures
The Effects of Smoothing on the Statistical Properties of the Large-Scale Cosmic Fileds
Creators: name: Bernardeau, F.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It has been shown that the large--scale correlation functions of the density field (and velocity divergence field) follow a specific hierarchy in the quasilinear regime and for Gaussian initial conditions (Bernardeau 1992). The exact relationships between the cumulants of the probability distribution functions (the so-called $S_p$ parameters) are however sensitive to the smoothing window function applied to the fields. In this paper, I present a method to derive the whole series of the $S_p$ parameters when the density field is smoothed with a top--hat window function. The results are valid for any power spectrum and any cosmological parameters. Similar calculations are presented for the velocity divergence field. The resulting shapes of the one--point probability distribution functions of the cosmic density and the velocity divergence fields are given as a function of the power spectrum and $Ω$. Simple analytical fits are proposed when the index of the power spectrum is -1. Comparisons with numerical simulations prove these analytical results to be extremely accurate.
description: 24 pages + 6 figures, uuencoded postscript file, also available by anonymous ftp from ftp.cita.utoronto.ca in directory /cita/francis/smoothing, CITA 94/7
Additional file 1 of Clinical outcomes and patterns of failure of head and neck mucosal melanoma treated with multiple treatment modalities
Creators: name: Xu, Qing-Qing
name: Lai, Yan-Zhen
name: Huang, Zi-Lu
name: Zeng, Zi-Yi
name: Zhang, Ya-Ni
name: Ou, Rui-Yao
name: Wu, Wen-Min
name: Chen, Lei
name: Lu, Li-Xia
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1. Figure S1. Survival outcomes between patients treated 10 years ago and within the last 10 years. Table S1. Distribution of the use of immunotherapy/targeted therapy in patients receiving surgery, radiotherapy, and chemotherapy, respectively.Table S2. Other studies evaluating the effect of multiple treatment in MMHN. Dose and target delineation.  The median radiotherapy dose was 58 Gy (range 30-70 Gy). Gross tumor volume (GTV) included the primary tumor and the enlarged lymph nodes, and GTV was expanded by 5-10 mm to generate the clinical tumor volume (CTV). For postoperative adjuvant radiotherapy, the CTV included the entire anatomical site where the tumors were located, and was expanded by 3-5 mm to generate the planning target volume (PTV). Cervical high-risk areas (including the number of metastatic lymph nodes ≥ 2, diameter ≥ 3 cm, extranodal lymph node invasion, and local recurrence after lymphatic dissection) were encompassed by the CTV.
Complementarity in Wormhole Chromodynamics
Creators: name: Lo, Hoi-Kwong
name: Lee, Kai-Ming
name: Preskill, John
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The electric charge of a wormhole mouth and the magnetic flux ``linked'' by the wormhole are non-commuting observables, and so cannot be simultaneously diagonalized. We use this observation to resolve some puzzles in wormhole electrodynamics and chromodynamics. Specifically, we analyze the color electric field that results when a colored object traverses a wormhole, and we discuss the measurement of the wormhole charge and flux using Aharonov-Bohm interference effects. We suggest that wormhole mouths may obey conventional quantum statistics, contrary to a recent proposal by Strominger.
description: 12 pages and 2 figures, phyzzx, CALT-68-1880
Combinatorial Stokes formulas via minimal resolutions
Creators: name: Hanke, Bernhard
name: Sanyal, Raman
name: Schultz, Carsten
name: Ziegler, Günter M.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Combinatorics (math.CO)
subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 13D02, 16e05, 05C15

description: We describe an explicit chain map from the standard resolution to the minimal resolution for the finite cyclic group Z_k of order k. We then demonstrate how such a chain map induces a "Z_k-combinatorial Stokes theorem", which in turn implies "Dold's theorem" that there is no equivariant map from an n-connected to an n-dimensional free Z_k-complex. Thus we build a combinatorial access road to problems in combinatorics and discrete geometry that have previously been treated with methods from equivariant topology. The special case k=2 for this is classical; it involves Tucker's (1949) combinatorial lemma which implies the Borsuk-Ulam theorem, its proof via chain complexes by Lefschetz (1949), the combinatorial Stokes formula of Fan (1967), and Meunier's work (2006).
description: 18 pages
Correlated Errors in the COBE DMR Sky Maps
Creators: name: Lineweaver, C. H.
name: Smoot, G. F.
name: Bennett, C. L.
name: Wright, E. L.
name: Tenorio, L.
name: Kogut, A.
name: Keegstra, P. B.
name: Hinshaw, G.
name: Banday, A. J.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The {\it COBE} DMR sky maps contain low-level correlated noise. We obtain estimates of the amplitude and pattern of the correlated noise from three techniques: angular averages of the covariance matrix, Monte Carlo simulations of two-point correlation functions, and direct analysis of the DMR maps. The results from the three methods are mutually consistent. The noise covariance matrix of a DMR sky map is diagonal to an accuracy of better than 1\%. For a given sky pixel, the dominant noise covariance occurs with the ring of pixels at an angular separation of $60 °$ due to the $60 °$ separation of the DMR horns. The mean covariance at $60 °$ is $0.45\% ^{+0.18}_{-0.14}$ of the mean variance. Additionally, the variance in a given pixel is $0.7\%$ greater than would be expected from a single beam experiment with the same noise properties. Auto-correlation functions suffer from a $\sim 1.5\; σ$ positive bias at $60 °$ while cross-correlations have no bias. Published {\it COBE} DMR results are not significantly affected by correlated noise. COBE pre-print 94-
description: 11 pages + 3 figures, post-script file
Interest of Natural Roots' Exploitation in the Optimization of the Prosthetic Balance: Case Series
Creators: name: Ines Saadellaoui
name: Yosra Mabrouk
name: Sana Bekri
name: Sameh Rezigui
name: Hiba Triki
name: Lamia Mansour
Publisher: name: Zenodo
Year: 2024

description: The conservation of residual roots, when their intrinsic and extrinsic values allow it, and their use as supports of additional means of retention greatly improve prosthetic balance. However, this therapeutic option requires a rigorous implementation and a correct choice of the retention systems better suited to the clinical situation. The aims of this paper were to present, through two clinical cases, interests of natural roots’ exploitation in the treatment of a large edentulous ridge and to describe the implementation of the axial attachment device.
The Basic and the Charge Density Wave Modulated Structures of NbS3-II
Creators: name: Zupanič, E.
name: van Midden, H. J. P.
name: van Midden, M.
name: Šturm, S.
name: Tchernychova, E.
name: Pokrovskii, V. Ya.
name: Zybtsev, S. G.
name: Nasretdinova, V. F.
name: Zaitsev-Zotov, S. V.
name: Chen, W. T.
name: Pai, W. W.
name: Bennett, J. C.
name: Prodan, A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The basic and the charge density wave (CDW) structures of the monoclinic $NbS_3-II$ polymorph were studied by synchrotron x-ray diffraction, ab-initio calculation, simulation of electron diffraction patterns and by atomic-resolution transmission electron and low-temperature scanning tunneling microscopies. It is shown that the basic structure belongs to the space group $P2_1/m$ and is described with a unit cell, formed of four pairs of symmetry-related trigonal prismatic (TP) columns ($a_0$ = 0.96509(8) nm, $b_0$ = 0.33459(2) nm, $c_0$ = 1.9850(1) nm, $β_0$ = 110.695(4) deg), with all Nb and S atoms in $2e$ special positions. The two CDWs, with $\vec{q_1}$ = (0, 0.298,0) and $\vec{q_2}$ = (0, 0.352, 0), form their own modulation unit cells ($a_m$ = $2a_0$, $b_m$ = $b_0/q_{jb}$, $c_m$ = $c_0$, $β_m$ = $β_0$) and are ordered pairwise along adjacent isosceles TP columns. The symmetries of both $\vec{q_j}$ modes belong to the space group $Cm$ and are related according to the $2a$ special positions. If considered as long-period commensurate, the entire modulated structure with both CDWs included is best described with an enlarged unit cell ($a$ = $2a_0$, $b$ = $37b_0$, $c$ = $c_0$, $β$ = $β_0$), with all Nb and S atoms in $1a$ positions of the space group $P1$.
description: v2.Minor changes to figures and text
Introduction and synthesis chapters of PhD dissertation on invasive alien species
Creators: name: Vaas, Jetske
Publisher: name: Zenodo
Year: 2019

description: Introduction chapter Chapter 6. Scientific synthesis. Leaving latency and moving manifest: understanding and resolving inertia Chapter 7. Practical synthesis. Recommendations regarding Coralita management for Saba and Statia From the PhD dissertation "Widely resented yet neglected: latent environmental problems. The case of an invasive alien vine on Saba and Statia" by Jetske Vaas, Utrecht University, December 2019.
CP Violating Form Factors for Three Gauge Boson Vertex in the Two Higgs Doublet and Left-Right symmetric Models
Creators: name: He, X. G.
name: Ma, J. P.
name: McKellar, B. H. J.
Publisher: name: arXiv
Year: 1992
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper we calculate the one loop contributions to the CP violating three gauge boson couplings in two-Higgs doublet and Left--Right symmetric models. In the two-Higgs doublet model only a P conserving and CP violating coupling is generated, and it can be large as $10^{-3}$. In the Left--Right symmetric model both P conserving and violating couplings are generated. Due to constraints on the $W_L$--$W_R$ mixing, these couplings are small.
description: 9 pages, Tex, UM-P-92/75, OZ-92/26
Feynman-Vernon model of a moving thermal environment
Creators: name: Patriarca, Marco
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: This paper reviews the formulation of the Feynman-Vernon model of linear dissipative systems for a standard Brownian particle moving in an external potential $V(x,t)$ and introduces the formulation of a generalized oscillator model of a Brownian particle coupled to a thermal environment moving with a given velocity $v_{env}$. Diffusion processes in a moving environment are of interest e.g. in the study of the motion of vortices in superfluids. The starting point of the paper is the formulation of the oscillator model that takes into account space and time invariance of a thermal environment [M. Patriarca, Statistical correlations in the oscillator model of quantum Brownian motion, Il Nuovo Cimento B, 111(1), 61-72 (1996), doi: 10.1007/BF02726201, arXiv:1801.02429], which has the property of being finite and consistent with the classical limit. The Langevin equation and the influence functional for a Brownian particle in a moving environment are derived.
description: Revised version with corrections and additional references and figures of the article: Marco Patriarca, "Feynman-Vernon model of a moving thermal environment", Physica E 29 (2005) 243250, doi 10.1016/j.physe.2005.05.021. 8 pages, 3 figures, 27 references
title: ADCO, Comptes du Petit-Cîteaux (1477-1491) (11 H 1179), f. 00110
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Archives Départementales De La Côte D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: comptes

description: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179), f. 00110, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Debiased orbit and absolute-magnitude distributions for near-Earth objects
Creators: name: Granvik, Mikael
name: Morbidelli, Alessandro
name: Jedicke, Robert
name: Bolin, Bryce
name: Bottke, William
name: Beshore, Edward
name: Vokrouhlicky, David
name: Nesvorny, David
name: Michel, Patrick
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The debiased absolute-magnitude and orbit distributions as well as source regions for near-Earth objects (NEOs) provide a fundamental frame of reference for studies of individual NEOs and more complex population-level questions. We present a new four-dimensional model of the NEO population that describes debiased steady-state distributions of semimajor axis, eccentricity, inclination, and absolute magnitude $H$ in the range $17
description: 33 pages, 28 figures, accepted for publication in Icarus
The Reality and Measurement of the Wavefunction
Creators: name: Unruh, W. G.
Publisher: name: arXiv
Year: 1993
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Using a simple version of the model for the quantum measurement of a two level system, the contention of Aharonov, Anandan, and Vaidman that one must in certain circumstances give the wavefunction an ontological as well as an epistemological significance is examined. I decide that their argument that the wave function of a system can be measured on a single system fails to establish the key point and that what they demonstrate is the ontological significance of certain operators in the theory, with the wave function playing its usual epistemological role.
description: 10pp
Doubly heavy baryon production at polarized photon collider
Creators: name: Yang, Zhong-Juan
name: Yao, Tao
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the inclusive production of doubly heavy baryon $Ξ_{cc}$ at polarized photon collider. Our results show that proper choice of the initial beam polarizations may increase the production rate of $Ξ_{cc}$ approximately 10%.
description: 9 pages, 5 figures