cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Antibacterial Activity of a Natural Clay Mineral against Burkholderia cepacia Complex and Other Bacterial Pathogens Isolated from People with Cystic Fibrosis
Creators: name: Behroozian, Shekooh
name: Zlosnik, James E. A.
name: Xu, Wanjing
name: Li, Loretta Y.
name: Davies, Julian E.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2025

description: There is an impending crisis in healthcare brought about by a new era of untreatable infections caused by bacteria resistant to all available antibiotics. Thus, there is an urgent need to identify novel antimicrobial agents to counter the continuing threat posed by formerly treatable infections. We previously reported that a natural mineral clay known as Kisameet clay (KC) is a potent inhibitor of the organisms responsible for acute infections. Chronic bacterial infections present another major challenge to treatment by antimicrobials, due to their prolonged nature, which results in repeated exposure to antibiotics and a constant selection for antimicrobial resistance. A prime example is bacteria belonging to the Burkholderia cepacia complex (Bcc), which particularly causes some of the most serious chronic lung infections in patients with cystic fibrosis (CF) associated with unpredictable clinical outcomes, poor prognosis, and high mortality rates. Eradication of these organisms from CF patients with limited effective antimicrobial options is a major challenge. Novel therapeutic approaches are urgently required. Here, we report the in vitro antibacterial activity of KC aqueous suspensions (1–10% w/v) and its aqueous extract (L100) against a collection of extensively and multi-drug resistant clinical isolates of Bcc, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia isolated from patients with CF. These findings present a potential novel therapy for further investigation in the clinic.
Utilizzo del protocollo RiVe per il monitoraggio della Vegetazione Riparia
Creators: name: Gumiero, Bruna
name: Cossu, Marco
name: Di Grazia, Francesco
name: Di Stefano, Cristian
Publisher: name: Zenodo
Year: 2024
Subjects: Citizen Science Italia
Citizen Science

description: Le zone ripariali sono il punto di incontro tra ecosistemi acquatici e terrestri dove avvengono una molteplicità di funzioni e servizi ecosistemici (ad es., la regolazione della qualità delle acque, il supporto alla biodiversità acquatica e riparia) oltre a rappresentare l’ossatura delle reti ecologiche. Una corretta gestione della fascia riparia aiuterebbe il ripristino della connettività ecologica e l’integrazione dei corridoi ecologici – specialmente nei contesti di pianura e negli agroecosistemi – in una vera e propria rete naturalistica trans-europea come previsto dalla Strategia Nazionale Biodiversità 2030. Nonostante questo, la vegetazione riparia non è inclusa tra i parametri elencati nella Direttiva Quadro sulle Acque (WFD 60/2000 UE) per la valutazione e il raggiungimento del buono stato ecologico dei corpi idrici a scala europea. Viene, pertanto, proposta una metodologia di monitoraggio della qualità della vegetazione riparia che si divide in tre fasi: una prima fase di formazione alle attività di campo, una seconda di raccolta dati con l’App RiVe o con la scheda di monitoraggio cartacea e una terza di analisi dei dati. I risultati possono essere riassunti nell’indice multi parametrico RiVe. L’indice varia da 0 a 120 e il punteggio finale si ottiene sommando i punteggi di sei parametri: 1) sezione del fiume, 2) altezza della vegetazione, 3) alberi caduti, 4) struttura del bosco, 5) copertura specie target nello strato arboreo e 6) copertura specie target nello strato arbustivo. La metodologia di monitoraggio proposta è stata sviluppata per progetti di Citizen science, ma può essere utilizzata anche da esperti come indagine rapida, integrata con analisi di telerilevamento. Le attività di citizen science hanno importanti benefici educativi e sociali in quanto migliorano la consapevolezza dei cittadini sulle pressioni che agiscono sui fiumi. Verranno presentati i risultati ottenuti dall’analisi dei dati provenienti dall’applicazione del protocollo RiVe in un tratto del torrente Idice nella zona est di Bologna.
Angle-Dependent Synthesis Method for Holographic Multi-Feed Antennas
Creators: name: Frey, Thomas
name: Döring, Maximilian
name: Riese, Nico
name: Waldschmidt, Christian
name: Chaloun, Tobias
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Holographic antenna
subject: Metasurface antenna
subject: Multi-beam antenna
subject: Glass technology
subject: Surface wave
subject: Leaky wave
subject: DDC 620 / Engineering & allied operations
subject: Antennas (Electronics)
subject: Monopulse radar
subject: Metasurfaces
subject: Radarantenne
subject: Monopulsverfahren
subject: Leckwelle
subject: Oberflächenwellenelement

description: A novel synthesis method for holographic multi-feed antennas is presented to combine all sub-holograms into an angle-dependent shared holographic aperture. In order to find the global error minimum between the shared holographic aperture and all ideal sub-holograms, a non-pixel-based genetic optimization is used. For a more accurately implementation of the analytical impedance tensor an eigenvector approach taking all tensor components into account is introduced. The optimized holographic antenna has four feeds for an exemplary integration into a 2D-monopulse radar system and is realized on a fused silica wafer due to its lower loss at millimeter-wave frequencies compared to Teflon-based materials. The antenna prototype provides a measured gain of 23 dBi, a polarization purity of 26 dB and a side-lobe level of 20 dB for feed 1, 2 and 4 is reached across 76 GHz−81 GHz. The S-parameters are measured from 60 GHz to 90 GHz , and a reflection coefficient of −14 dB and an inter-port coupling <−38 dB are achieved. The measured 2D-monopulse patterns provide a FOV of ang 10, the sum beam has a gain of 26 dBi leading to an aperture efficiency of 45 % and the differential beams show a null depth of 30 dB.
Cross-cultural differences in academic self-efficacy and its sources across socialization contexts
Creators: name: Gebauer, Miriam Marleen
name: McElvany, Nele
name: Köller, Olaf
name: Schöber, Christian
Publisher: name: TU Dortmund
Year: 2021
Subjects: subject: Immigrant backgrounds
subject: Socialization contexts
subject: Sources of self-efficacy
subject: Student academic self-efficacy
subject: Social cognitive theory
subject: 370
subject: Migrationshintergrund
subject: Selbstwirksamkeit |
subject: Sozialisation |
subject: Sozial-kognitive Lerntheorie |

description: This study investigated how as reported by Bandura (Self-efficacy: The exercise of control Freeman, 1997) sources of self-efficacy differ across socialization contexts for German students with diverse immigrant backgrounds. We measured all four sources of academic self-efficacy in three socialization contexts for students of former Soviet Union and Turkish descent as well as without an immigrant background, assuming that we would find differences between these groups. Participants were 1217 seventh-grade students in Germany. Multigroup structural equation analyses with latent variables revealed the differential importance of socialization contexts for the relation between academic self-efficacy and its sources across groups. For students of former Soviet Union and Turkish descent, verbal or social persuasion is the strongest contributing factor for academic self-efficacy, whereas for students without an immigrant background, it is mastery experience. In the school context, significant relationships between sources of self-efficacy and academic self-efficacy could only be observed for students without an immigrant background. The results both support and refine Bandura’s social cognitive theory by showing that self-related constructs function differently in students with culturally diverse immigrant backgrounds.
description: Social psychology of education,;Band 24. 2021, Heft 6, Seiten 1407-1432
title: Scottish Crown Estate Bill - Evidence to Scottish Parliament Environment, Climate Change and Land Reform Committee
Creators: name: Bell, Rebecca
name: Brownsort, Peter
name: Haszeldine, R Stuart
name: Parmiter, Philippa
Publisher: name: SCCS
Year: 2018
Subjects: subject: CCS
subject: carbon capture and storage
subject: Scottish Crown Estate
subject: Crown Estate Scotland
subject: Scottish Crown Estate Bill
subject: CCUS

description: We recognise that there may be some benefit in some Scottish Crown Estate assets being managed by local authorities or other bodies specified in the Bill. However, we consider that offshore energy and energy-related assets and investments, including CO2 storage rights and leasing rights for oil and gas pipelines, should be managed by CES as a single integrated portfolio and not have their management further devolved. We consider that the current Bill does not provide adequate safeguards against the break-up of offshore and coastal assets, and we suggest here some ways that the Bill could be improved.
description: We recognise that there may be some benefit in some Scottish Crown Estate assets being managed by local authorities or other bodies specified in the Bill. However, we consider that offshore energy and energy-related assets and investments, including CO2 storage rights and leasing rights for oil and gas pipelines, should be managed by CES as a single integrated portfolio and not have their management further devolved. We consider that the current Bill does not provide adequate safeguards against the break-up of offshore and coastal assets, and we suggest here some ways that the Bill could be improved.
Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity
Creators: name: Saeidi, Ayoub
name: Nouri-Habashi, Akbar
name: Razi, Omid
name: Ataeinosrat, Ali
name: Rahmani, Hiwa
name: Mollabashi, Shirin Shirzad
name: Bagherzadeh-Rahmani, Behnam
name: Aghdam, Shahin Mahmoudi
name: Khalajzadeh, Leila
name: Al Kiyumi, Maisa Hamed
name: Hackney, Anthony C.
name: Laher, Ismail
name: Heinrich, Katie M.
name: Zouhal, Hassane
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2025

description: The aim of this study was to investigate the effects of 12 weeks of high-intensity training with astaxanthin supplementation on adipokine levels, insulin resistance and lipid profiles in males with obesity. Sixty-eight males with obesity were randomly stratified into four groups of seventeen subjects each: control group (CG), supplement group (SG), training group (TG), and training plus supplement group (TSG). Participants underwent 12 weeks of treatment with astaxanthin or placebo (20 mg/d capsule daily). The training protocol consisted of 36 sessions of high-intensity functional training (HIFT), 60 min/sessions, and three sessions/week. Metabolic profiles, body composition, anthropometrical measurements, cardio-respiratory indices and adipokine [Cq1/TNF-related protein 9 and 2 (CTRP9 and CTRP2) levels, and growth differentiation factors 8 and 15 (GDF8 and GDF15)] were measured. There were significant differences for all indicators between the groups (p < 0.05). Post-hoc analysis indicated that the levels of CTRP9, CTRP2, and GDF8 were different from CG (p < 0.05), although levels of GDF15 were similar to CG (p > 0.05). Levels of GDF8 were similar in the SG and TG groups (p > 0.05), with reductions of GDF15 levels in both training groups (p < 0.05). A total of 12 weeks of astaxanthin supplementation and exercise training decreased adipokines levels, body composition (weight, %fat), anthropometrical factors (BMI), and improved lipid and metabolic profiles. These benefits were greater for men with obesity in the TSG group.
title: Richards Piano Roll Collection finding aid
Creators: name: Staff, Fine Arts Library
Publisher: name: The University of Texas at Austin
Year: 2025
Subjects: subject: player piano rolls
subject: Welte Mignon
subject: Ampico
subject: Duo-Art
subject: QRS
subject: Themodist-Metrostyle

description: This collection includes 857 player piano rolls from a variety of brands, including but not limited to Ampico, Welte Mignon, 88-Note Themodist-Metrostyle, and QRS.
Data on the Environment 2015
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: Klima
Boden
Landwirtschaft
Abfall
Nachhaltigkeit

description: Environmental policy requires great staying power not only in terms of climate protection. A look at air pollution control and water protection shows that while harmful emissions to the environment are decreasing in many areas, this is no reason to sound the all clear. For example, only ten percent of rivers and streams in Germany and only about one percent of examined sections of North and Baltic Sea coasts exhibit good ecological status, mainly because nutrient loads are still too high.
Quelle: www.umweltbundesamt.de
Supplementary document for Imaging Deeper than the Transport Mean Free Path with Multiphoton Microscopy - 5572407.pdf
Creators: name: Akbari, Najva
name: rebec, mihailo
name: Xia, Fei
name: Xu, Chris
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Applied Physics
Biomedical Instrumentation

description: Supplementary equations and figures.
Food Web Connectivity in a Mangrove–Seagrass–Patch Reef (MSP) Seascape: Lessons from a Tropical Back-Reef in Puerto Rico
Creators: name: Quigg, Antonietta
name: Wells, R. J. David
name: Rooker, Jay R.
name: Hill, Ronald L.
name: Kitchens, Larissa L.
name: Dance, Michael A.
name: Moulton, David L.
name: Sanchez, Phillip J.
name: Ferreira, Beatrice Padovani
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2024

description: Alterations to the functions and connectivity of mangrove–seagrass–patch reef (MSP) seascapes have the potential to impact the survival, foraging activities, and movement of reef-dependent invertebrates (e.g., crabs and shrimp) and fishes. In the current study, we examined carbon flow in the Guánica Biosphere Reserve in southwestern Puerto Rico using pigment analysis of particulate organic matter and stable isotope analysis of carbon (¹³C) and nitrogen (¹⁵N) in flora and fauna1 . Several lines of evidence pointed to N₂ fixers (cyanobacteria) being important for fueling primary productivity in this oligotrophic ecosystem including low (<0.7 μg L⁻¹) chlorophyll, prevalence of cyanobacteria based on pigment signatures, and the isotope signatures of seagrass and red mangrove leaf tissue (enriched ¹⁵N values) and consumers (depleted ¹⁵N values). Food web mixing models based on stable isotopes (¹³C and ¹⁵N) revealed that multiple producers (phytoplankton, benthic microalgae, seagrasses, etc.) contributed organic matter to the consumers (zooplankton, invertebrates, and fishes) in the MSP seascape at the center of the reserve. Contribution estimates for common benthic invertebrates (crabs and shrimp) were taxon-specific, and the highest input was generally linked to particulate organic matter (POM) and benthic microalgae (BMA)/seagrass producer categories, although meaningful mangrove contribution was observed for some taxa. Similarly, contribution estimates for fishes were highest for POM and BMA/seagrass, with the latter producer category being more important for species known to migrate from mangroves or patch reefs to seagrass beds at night (bluestriped grunt, French grunt, and white grunt). Although all fish investigated were observed in mangrove prop-root habitats, input of organic matter from mangroves to these consumers was typically limited for most of the species examined. Understanding these complex seascapes contributes to our understanding of the ecology of these vital ecosystems.
NMR Based Foodomics to Investigate the Digestibility of Protein-Rich Food Products
Creators: name: Marcolini, Elena <1986>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2015
Subjects: CHIM/03 Chimica generale e inorganica

description: Nowadays, in developed countries, the excessive food intake, in conjunction with a decreased physical activity, has led to an increase in lifestyle-related diseases, such as obesity, cardiovascular diseases, type -2 diabetes, a range of cancer types and arthritis. 
The socio-economic importance of such lifestyle-related diseases has encouraged countries to increase their efforts in research, and many projects have been initiated recently in research that focuses on the relationship between food and health. 
Thanks to these efforts and to the growing availability of technologies, the food companies are beginning to develop healthier food. The necessity of rapid and affordable methods, helping the food industries in the ingredient selection has stimulated the development of in vitro systems that simulate the physiological functions to which the food components are submitted when administrated in vivo. One of the most promising tool now available appears the in vitro digestion, which aims at predicting, in a comparative way among analogue food products, the bioaccessibility of the nutrients of interest.. The adoption of the foodomics approach has been chosen in this work to evaluate the modifications occurring during the in vitro digestion of selected protein-rich food products. The measure of the proteins breakdown was performed via NMR spectroscopy, the only techniques capable of observing, directly in the simulated gastric and duodenal fluids, the soluble oligo- and polypeptides released during the in vitro digestion process. The overall approach pioneered along this PhD work, has been discussed and promoted in a large scientific community, with specialists networked under the INFOGEST COST Action, which recently released a harmonized protocol for the in vitro digestion. NMR spectroscopy, when used in tandem with the in vitro digestion, generates a new concept, which provides an additional attribute to describe the food quality: the comparative digestibility, which measures the improvement of the nutrients bioaccessibility.
Supplementary document for Imaging Deeper than the Transport Mean Free Path with Multiphoton Microscopy - 5572407.pdf
Creators: name: Akbari, Najva
name: rebec, mihailo
name: Xia, Fei
name: Xu, Chris
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Applied Physics
Biomedical Instrumentation

description: Supplementary equations and figures.
“I’m Trying to be There for my Kids” : A Needs Analysis of Fathers Who Experience Health Inequities in Vancouver, Canada
Creators: name: Darroch, Francine E.
name: Oliffe, John Lindsay
name: Montaner, Gabriela Gonzalez
name: Webb, Jessica M.
Publisher: name: Sage
Year: 2023

description: To better understand the needs of fathers who experience health inequities, we individually interviewed fathers, mothers, and service providers about their perspectives of supports for men in Vancouver’s Downtown Eastside, one of the most disadvantaged groups in Canada. Using a gender lens, thematic analysis of transcribed interviews with three cohorts revealed the following themes: “we need a He-way”: Fathers arguing for men-friendly services; “I had to do all the hard work”: Mothers identifying relational impacts of fathers’ barriers to services; “there is nothing out there for them”: Service providers acknowledging the lack of father-focused programs. Findings highlight the need for, and challenges to creating accessible, gender specific, father focused programs and services to best support men and families within the complex contexts of experiencing significant health inequities. This work illustrates how gender-based analyses can guide strategies for health promotion programs that will ultimately support fathers, mothers and their families.
Progetto "SeaCleaner": coniugare ricerca, educazione e sensibilizzazione sul tema dell'impatto antropogenico sull'ambiente marino
Creators: name: Merlino, Silvia
name: Locritani, Marina
Publisher: name: Zenodo
Year: 2024
Subjects: Citizen Science Italia
Citizen Science
Sea

description: ll problema dell’impatto antropogenico sull’ambiente marino è un tema su cui si è posta, negli ultimi anni, sempre più l’attenzione politica, mediatica, sociale e scientifica. Il progetto “seaCleaner"(https://sites.google.com/view/seacleaner/home-page) nasce nel 2013 con la volontà di coniugare diversi aspetti, tutti parimenti importanti, legati a questo tema: la ricerca scientifica, che ha bisogno di molti dati; l’educazione, che, nel decennio dell’ oceano (2021-2030) si trova a dover affrontare tematiche fino ad ora non inserite fra i curricula scolastici; la sensibilizzazione al problema di cittadini spesso all’oscuro di molti aspetti legati all’uso e conferimento di oggetti in plastica e bioplastica. Nato da una esperienza scolastica di “alternanza scuola-lavoro” (oggi PCTO) con alcune classi di scuola superiore di la Spezia, SeaCleaner cerca, da 10 anni, di coniugare questi tre aspetti, proponendo esperienze partecipative, progetti di monitoraggio e elaborazione dati a studenti, insegnanti e volontari, creando sinergie fra chi si occupa di tematiche ambientali, la scuola e i ricercatori. I protocolli “SeaCleaner” sono stati adoperati per raccogliere dati rigorosi inseriti in database di ricerca dedicati, per pubblicare articoli scientifici, per coinvolgere studenti nella raccolta ed analisi dei dati, per presentare questi ultimi durante manifestazioni e conferenze, per realizzare (o prendere parte a) documentari scientifici. Attualmente alcuni dati sono anche utilizzati da associazioni come “Spazzapnea”, Marevivo e Legambiente, a partire dalle macro e microplastiche in spiaggia a quelle sui fondali marini. Le scuole coinvolte negli anni sono state più di 40, sia in Liguria che nelle 4 regioni limitrofe, nonché alcune in provincie del sud Italia. In questi anni di attività, SeaCleaner ha ricevuto vari riconoscimenti, fra cui il premio per il miglior progetto di Alternanza Scuola-Lavoro nel 2013; è stato selezionato dal progetto EU “NEWSERA” fra le attività di CS a livello nazionale; ha presenziato Padiglione Italia- EXPO DUBEI 2021, con il documentario “MARINE RUBBISH” che ne illustra le tematiche e metodologie; ha partecipato (e partecipa tutt’ ora) alle docuserie per famiglie dedicata al tema della plastica in mare “Luna sul Mare”. È stato “consulente scientifico” per la realizzazione di contenuti e allestimento della Mostra “La Plastica e Noi”, Museo di Storia naturale dell’Università di Pisa, Calci, da Giugno 2020 a Giugno 2021.
Subcapsular liver hematoma: a rare complication of HELLP syndrome
Creators: name: Ikram, Taam
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Abdomen
subject: Genital / Reproductive system female
subject: CT
subject: Ultrasound
subject: Diagnostic procedure
subject: Haemorrhage

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 34 years
description: Clinical History: A 34 year-old women, gravid 2, parity 1, was admitted at 34 weeks of gestation. She complained of epigastric pain and headache.The blood pressure measuring 170/100 mmHg, the laboratory analysis revealed a hepatic dysfunction, haemolysis (ALAT: 280UI... Final Diagnosis: Subcapsular liver hematoma (complication of HELLP syndrome)
Valleys of friction: a regional consideration of Israelite and Philistine interrelationship during their early encounters in the northern Shephelah
Creators: name: Hardesty, Edgar Berkeley
Publisher: name: Maryland Shared Open Access Repository
Year: 2016

description: (Ph. D.) -- Towson University, 2015.
description: Dr. William G. Dever, in his book “What Did the Biblical Writers Know and When Did They Know It?” expressed in part the issue to be addressed by this study. Speaking of “Primary” and “Secondary” Sources and the separate yet parallel disciplines of Biblical Interpretation and Archaeology he comments, ´Biblical scholars, until recently, trained primarily as philologians, have always tended to overvalue texts as the more ‘objective’ evidence, even when they acknowledge as they must the inherent differences in interpretation. In my judgment, this reflects a certain naïveté about how texts serve as ‘symbols’ and an abysmal ignorance of how artifacts can serve in the same way” (Dever, 2001, p.87).

This statement could also apply to the trained archaeologist who often undervalues the biblical text when evaluating the physical data uncovered in his or her professional activities. Thus, the extant literature addressing Philistine and Israelite interaction tends to reflect a parochial and often isolated view confined to the given researcher’s discipline. This dissertation will add a third parallel discipline, often neglected or ignored altogether, to the two aforementioned disciplines. The biblical narrative and the archaeologist’s understanding of material remains both exist within a “physical setting” which can be defined in terms of geography, geology and topography. The elements of that definition have a direct contextual connection with the Biblical text and the archaeological data. It is the purpose of this dissertation to combine the geographic environment, the Biblical narrative and the physical remains to further define and understand the Israelite and Philistine interrelationships during their early encounters in the northern Shephelah.
description: http://library.towson.edu/cdm/ref/collection/etd/id/47076
Effect of Metal Atom in Zeolitic Imidazolate Frameworks (ZIF-8 & 67) for Removal of Dyes and Antibiotics from Wastewater: A Review
Creators: name: Pouramini, Zahra
name: Mousavi, Seyyed Mojtaba
name: Babapoor, Aziz
name: Hashemi, Seyyed Alireza
name: Lai, Chin Wei
name: Mazaheri, Yousef
name: Chiang, Wei-Hung
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2024

description: The use of antibiotics and dyes has resulted in severe water pollution and health risks; therefore, it is urgent to remove them from water sources. Among the most common methods for removing harmful water contaminants, adsorption and photodegradation are the most economical, simple, and reusable. Due to their high porosity, adjustability, and crystal structure, metal-organic frameworks (MOFs) are one of the effective adsorbents and photocatalysts. A typical MOF material is zeolitic imidazolate framework-8/67 (ZIF-8 and ZIF-67), comprising essentially of the metal atoms Zn and 2-methylimidazole (2-MIM). ZIF-8 and ZIF-67 have unique properties that make them efficient in water treatment due to high adsorption capacities and being good hosts for photocatalytic materials. In this article, a review study of the design and methods of synthesis of ZIF-8 and ZIF-67 composites is presented. An introduction to the current research on the role of ZIF-8 and ZIF-67 compounds as adsorbents and photocatalysts for wastewater pollution removal is provided. In this review study, we aim to supply a mechanistic perspective on the use of ZIF-8/67 composites in wastewater purification and present novel visions for the development of extremely effective ZIF-8/67-based adsorbents and photocatalysts. To unlock the full potential of ZIF-8/67 composites in dye and antibiotic removal and water recycling, current difficulties will be discussed in detail.
title: Human biomonitoring initiative (HBM4EU): Human biomonitoring guidance values (HBM-GVs) derived for cadmium and its compounds
title: Human biomonitoring initiative (HBM4EU): Human biomonitoring guidance values (HBM-GVs) derived for cadmium and its compounds
titleType: AlternativeTitle
Creators: name: Apel, Petra
name: Lamkarkach, Farida
name: Ougier, Eva
name: Kolossa-Gehring, Marike
name: Garnier, Robert
name: Lange, Rosa
Publisher: name: My University
Year: 2021
Subjects: Human-Biomonitoring
Cadmium
Gesundheitliche Auswirkungen
Niere
Neurotoxizität
Expositionsabschätzung

description: Aims The methodology agreed within the framework of the HBM4EU project is used in this work to derive HBM-GVs for the general population (HBM-GVGenPop) and for workers (HBM-GVWorker) exposed to cadmium (Cd) and its compounds. Methods For Cd, a significant number of epidemiological studies with doseââą Ìresponse relationships are available, in particular for kidney effects. These effects are described in terms of a relation between urinary Cd (U-Cd) or blood Cd (B-Cd) levels and low molecular weight proteinuria (LMWP) markers like beta-2-microglobulin (Î22M) and retinol-binding protein (RBP). In order to derive HBM-GVs for the general population and workers, an assessment of data from evaluations conducted by national or international organisations was undertaken. In this work, it appeared relevant to select renal effects as the critical effect for the both groups, however, differences between general population (including sensitive people) and workers (considered as an homogenous population of adults who should not be exposed to Cd if they suffer from renal diseases) required the selection of different key studies (i.e. conducted in general population for HBM-GVGenPop and at workplace for HBM-GVWorker). Results and conclusions For U-Cd, a HBM-GVGenPop of 1 (my)g/g creatinine (creat) is recommended for adults older than 50 years, based on a robust meta-analysis performed by EFSA (EFSA, 2009a). To take into account the accumulation of Cd in the human body throughout life, threshold or 'alert' values according to age were estimated for U-Cd. At workplace, a HBM-GVWorker of 2 (my)g/g creat is derived from the study of Chaumont et al., (2011) for U-Cd, and in addition to this recommendation a HBM-GVworker for B-Cd of 5 Ìg/L is also proposed. The HBM-GVWorker for U-Cd is similar to the biological limit value (BLV) set by the new amendment of the European Carcinogens and Mutagens Directive in June 2019 (2 (my)g/g creat for U-Cd). © 2021 The Authors
YANGI O'ZBEKISTONDA YOSHLAR SIYOSATINI ZAMON TALABLARIDAN KELIB CHIQIB TAKOMILLASHTIRISHNING DOLZARBLIGI.
Creators: name: Madraximov, Jahongir
Publisher: name: Zenodo
Year: 2024

description: Rivojlanayotgan ijtimoiy-iqtisodiy landshaft va o‘sib kelayotgan yosh avlod ehtiyojlarini hisobga olgan holda, yangi O‘zbekistonda yoshlarga oid siyosatni takomillashtirishning dolzarbligi birinchi o‘rinda turadi. O‘zbekiston yangi islohot va modernizatsiya davriga o‘tayotgan bir paytda yoshlar oldida turgan vazifa va imkoniyatlarni samarali hal etish uchun yoshlarga oid siyosatni zamon talablari bilan uyg‘unlashtirish zarur.
The Implication of Topoisomerase II Inhibitors in Synthetic Lethality for Cancer Therapy
Creators: name: Matias-Barrios, Victor M.
name: Dong, Xuesen
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2025

description: DNA topoisomerase II (Top2) is essential for all eukaryotic cells in the regulation of DNA topology through the generation of temporary double-strand breaks. Cancer cells acquire enhanced Top2 functions to cope with the stress generated by transcription and DNA replication during rapid cell division since cancer driver genes such as Myc and EZH2 hijack Top2 in order to realize their oncogenic transcriptomes for cell growth and tumor progression. Inhibitors of Top2 are therefore designed to target Top2 to trap it on DNA, subsequently causing protein-linked DNA breaks, a halt to the cell cycle, and ultimately cell death. Despite the effectiveness of these inhibitors, cancer cells can develop resistance to them, thereby limiting their therapeutic utility. To maximize the therapeutic potential of Top2 inhibitors, combination therapies to co-target Top2 with DNA damage repair (DDR) machinery and oncogenic pathways have been proposed to induce synthetic lethality for more thorough tumor suppression. In this review, we will discuss the mode of action of Top2 inhibitors and their potential applications in cancer treatments.
Supplementary document for Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy - 5572448.pdf
Creators: name: de Vito, Giuseppe
name: Turrini, Lapo
name: Muellenbroich, Marie-Caroline
name: ricci, pietro
name: Sancataldo, Giuseppe
name: Mazzamuto, Giacomo
name: Tiso, Natascia
name: Sacconi, Leonardo
name: Fanelli, Duccio
name: Silvestri, Ludovico
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Animal Neurobiology

description: Supplemental Document
Supplementary document for Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy - 5572448.pdf
Creators: name: de Vito, Giuseppe
name: Turrini, Lapo
name: Muellenbroich, Marie-Caroline
name: ricci, pietro
name: Sancataldo, Giuseppe
name: Mazzamuto, Giacomo
name: Tiso, Natascia
name: Sacconi, Leonardo
name: Fanelli, Duccio
name: Silvestri, Ludovico
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Animal Neurobiology

description: Supplemental Document
ARCHÉ vs Safe Superintelligence Inc. (SSI): A Philosophical and Ontological Comparison
Creators: name: Ioffe, Yuriy
Publisher: name: Zenodo
Year: 2025

description: This document compares the philosophical foundations of the ARCHÉ model with the design logic of Safe Superintelligence Inc. (SSI), founded by Ilya Sutskever. Both systems aim to rethink the future of intelligent systems — ARCHÉ through resonant subjectivity, SSI through a guaranteed safe superintelligence. The comparison reveals deep structural and ethical differences, as well as potential conceptual bridges between them.
MPEC 2024-Q34 : COMET P/2010 WK = P/2010 PB57 = P/2024 O3 (LINEAR)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: COMET P/2010 WK = P/2010 PB57 = P/2024 O3 (LINEAR)

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
An open approach to modular control systems for agile automations
Creators: name: Dimitropoulos, George P.
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 91399 Mechanical Engineering not elsewhere classified
subject: FOS: Mechanical engineering

description: This research has investigated methods and technologies to improve the agility of automated production systems with particular reference to open systems, modular control, and parametric mechatronic software. A critical review of current methods and technologies, both in available literature and the study of prototype modular control systems available in the Manufacturing Systems Integration Research Institute (MSIRI) of Loughborough University, revealed that production agility could be improved by enabling adaptability at the levels of control system integration and control module configuration. The practise to parametrically link the transition logic of many autonomous modules together forming integrated systems on the basis of functional components was known to improve adaptability. The research found that adaptability could be further increased if all other logic elements within the components became reconfigurable as well. Proprietary control infrastructures used in the prior art were identified as a limitation on adaptability. These findings led to the design and implementation of the universal mechatronic software (UMS), in a manner that supports a wide range of mainstream computing infrastructures, features fully parametric logic, and connects modules through open network protocols. This makes it possible to: 1) Design, simulate and parametrise clusters of mechatronic systems using uniform models. 2) Use the UMS in all control modules regardless of module function and cluster architecture. 3) Reuse legacy systems and existing networks in UMS controlled systems without modifications. This research quantified adaptability in automatic production control systems, contributed to science by proposing mathematical models that focus on maximising adaptability, and contributed to technology by implementing these models in the form of parametrisable control software which when used for production control promises to deliver higher adaptability than its prior art.
CSCCE Community Manager Case Study: Maria Cruz
Creators: name: Cruz, Maria
name: Pratt, Katie
name: Sidik, Saima
name: Woodley, Lou
Publisher: name: Zenodo
Year: 2022
Subjects: CSCCE
CSCCE Community Manager Case Study
NWO
Dutch Research Council
scientific community manager

description: This case study features Maria Cruz, Senior Open Science and Data Policy Advisor for the Dutch Research Council (NWO). It is part of an ongoing collection created by the Center for Scientific Collaboration and Community Engagement. It is part of our research into the nature of community manager roles and how they vary across the STEM ecosystem. You can find out more about the project, and view additional case studies in the collection, on our website. To find the case studies on Zenodo, click here. About CSCCE The Center for Scientific Collaboration and Community Engagement (CSCCE) champions the importance of human infrastructure for effective collaboration in STEM. We provide training and support for the people who make scientific collaborations succeed at scale - and we also research the impact of these emerging roles. Find out more about us on our website: CSCCE.org.
Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators
Creators: name: Chu, Mu-Tzu
name: Chang, Wan-Chun
name: Pao, Shih-Cheng
name: Hung, Shuen-Iu
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2024

description: Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell activation. The clinical presentations of such hypersensitivity are various and range from mild reactions (e.g., maculopapular exanthema (MPE) and fixed drug eruption (FDE)), to drug-induced liver injury (DILI) and severe cutaneous adverse reactions (SCARs) (e.g., Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP)). The common culprits of delayed drug hypersensitivity include anti-epileptics, antibiotics, anti-gout agents, anti-viral drugs, etc. Delayed drug hypersensitivity is proposed to be initiated by different models of molecular recognition, composed of drug/metabolite antigen and endogenous peptide, HLA presentation, and T cell receptor (TCR) interaction. Increasing the genetic variants of HLA loci and drug metabolic enzymes has been identified to be responsible for delayed drug hypersensitivity. Furthermore, preferential TCR clonotypes, and the activation of cytotoxic proteins/cytokines/chemokines, are also involved in the pathogenesis of delayed drug hypersensitivity. This review provides a summary of the current understanding of the molecular recognition, genetic susceptibility, and immune mediators of delayed drug hypersensitivity.
Isothermal stress-relief and stress-relaxation of cold-extruded mild steel rods
Creators: name: Adeyemi, Michael B.
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 91399 Mechanical Engineering not elsewhere classified
subject: FOS: Mechanical engineering

description: In the present investigation, the kinetics of stress-relief in cold-extruded mild steel rods have been obtained by the longitudinal slitting method, the fractional residual stress remaining as a function of heating time being estimated at each annealing temperature. Corrections have been applied for the time taken to reach the required annealing temperatures. It is found that stress-relief is substantially completed at approximately 500°C in one hour with little change in hardness from that of the as-extruded rod. The residual stress distribution has also been measured, using the Sach's bore-out method. Stress-relaxation and strain rate cycling tests have been conducted on the cold-extruded and annealed mild steel rods at temperatures ranging from room temperature to 500°C. Attempts are made to correlate the results of the stress-relaxation and stress-relief tests. Theoretical and experimental approaches, based on constant strain are presented. Some of the theoretical and experimental analyses, which have been successfully applied to stress-relaxation tests at low temperature (i.e. below room temperature) are found to be inadequate in analysing the stress-relaxation tests on both the cold extruded and annealed mild steel rods over the test temperature range because the assumptions, on which they are based become invalid. The apparent activation energies, as measured from the temperature dependence of the rate of reduction in residual stress or stress relaxation, for both the stress-relaxation and stress-relief tests are approximately equal over the same temperature considered and are found to increase as the residual stress or applied stress decreases. The same mechanisms are suggested to be operative in both the stress-relief and stress-relaxation tests. Dislocation-point defects interaction mechanism has been suggested to operate at the low temperature of the test temperature range, while the higher temperatures have been associated with dislocation climb-controlled processes. Hot tensile tests have been conducted on the extruded specimens while room temperature tensile tests have also been performed on specimens previously subjected to stress-relaxation tests. Very small changes in hardness, due to a precipitation phenomenon, occur during stress relief. Electron transmission examinations of the extruded and stress-relaxed extruded specimens are presented.
Multimedia and learning: an empirical investigation for media combinations and learning
Creators: name: Al-Sharrah, Ahmed
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Developments in distance learning education have revealed difficulties in providing education “at a distance”. It has been suggested that these deficiencies might be overcome through the use of better-designed interfaces exploiting the capabilities of multimedia interface design techniques. A framework for characterising media is identified and the Dual Coding Theory of Cognition is identified as a possible theoretical basis for examining the effects of media on learning. A pilot experiment compared the effects of teaching identical material on statistics in both a face-to-face manner and wholly on-line. The objective of the experiment was to determine what problems emerged in carrying out such experimentation and what the student response would be. This was then followed by a set of empirical investigations on how different combinations of media affect learning outcomes in computer-based education. In particular, it examined if there is a relationship between the media combinations and the learning styles of the students. Specifically the following hypotheses were tested. (1) Presentations using sound and diagrams result in better recall than text and diagrams, and text-only for modules presenting statistical knowledge. (2) Presentations using text and diagrams results in better recall than text-only presentations for each valid learning unit. (3) Specific styles of learning have better recall than others for each valid learning unit. These hypotheses were examined in a large-scale experiment in which three different presentation styles were presented (Voice over+Diagrams, Text + Diagrams, and Text Only) to large numbers of students. The results show firstly that there are indeed media effects when the same information is presented in different ways as predicted by Dual Coding Theory. The combination of voice and diagrams resulted in superior recall of knowledge in all cases and was very persistent over all subject groups and conditions. Finally, a significant effect was observed in recall between Sensor and Intuitor Learners. The work suggests that Dual Coding theory can provide a theoretical framework upon which media combinations can be incorporated into interface design.
Canadian Physicians’ Use of Intramuscular Botulinum Toxin Injections for Shoulder Spasticity: A National Cross-Sectional Survey
Creators: name: Kassam, Farris
name: Lim, Brendan
name: Afroz, Sadia
name: Boissonnault, Ève
name: Reebye, Rajiv
name: Finlayson, Heather
name: Winston, Paul
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2025

description: Spasticity of the upper extremity can result in severe pain, along with many complications that can impair a patient’s activities of daily living. Failure to treat patients with spasticity of the upper limb can result in a decrease in the range of motion of joints and contracture development, leading to further restriction in daily activities. We aimed to investigate the practice patterns of Canadian physicians who utilize Botulinum toxin type-A (BoNT-A) injections in the management of shoulder spasticity. 50 Canadian Physical Medicine and Rehabilitation (PM&R) physicians completed a survey with an estimated completion rate of (36.23%). The demographics of the survey participants came from a variety of provinces, clinical settings, and patient populations. The most common muscle injected for shoulder adduction and internal rotation spasticity was the pectoralis major, this was followed by latissimus dorsi, pectoralis minor, subscapularis and teres major. Injection of BoNT-A for problematic post-stroke shoulder spasticity was common, with (81.48%) of participants responding that it was always or often used in their management of post-stroke spasticity (PSS). Dosing of BoNT-A demonstrated variability for the muscle injected as well as the type of toxin used. The goals of the patients, caregivers, and practitioners were used to help guide the management of these patients. As a result, the practice patterns of Canadian physicians who treat shoulder spasticity are varied, due to numerous patient factors. Future studies are needed to analyze optimal treatment patterns, and the development of algorithms to standardize care.
Supplementary document for Effect of detection angle and substrate in the polarization analysis of dipole emission - 5572747.pdf
Creators: name: Dasallas, Lean
name: Jaculbia, Rafael
name: Balois, Maria Vanessa
name: Garcia, Wilson
name: Hayazawa, Norihiko
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document