cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Neural Chronos ODE: Unveiling Temporal Patterns and Forecasting Future and Past Trends in Time Series Data
Creators: name: Coelho, C.
name: Costa, M. Fernanda P.
name: Ferrás, L. L.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences
subject: I.5.1; G.1.7

description: This work introduces Neural Chronos Ordinary Differential Equations (Neural CODE), a deep neural network architecture that fits a continuous-time ODE dynamics for predicting the chronology of a system both forward and backward in time. To train the model, we solve the ODE as an initial value problem and a final value problem, similar to Neural ODEs. We also explore two approaches to combining Neural CODE with Recurrent Neural Networks by replacing Neural ODE with Neural CODE (CODE-RNN), and incorporating a bidirectional RNN for full information flow in both time directions (CODE-BiRNN), and variants with other update cells namely GRU and LSTM: CODE-GRU, CODE-BiGRU, CODE-LSTM, CODE-BiLSTM.
 Experimental results demonstrate that Neural CODE outperforms Neural ODE in learning the dynamics of a spiral forward and backward in time, even with sparser data. We also compare the performance of CODE-RNN/-GRU/-LSTM and CODE-BiRNN/-BiGRU/-BiLSTM against ODE-RNN/-GRU/-LSTM on three real-life time series data tasks: imputation of missing data for lower and higher dimensional data, and forward and backward extrapolation with shorter and longer time horizons. Our findings show that the proposed architectures converge faster, with CODE-BiRNN/-BiGRU/-BiLSTM consistently outperforming the other architectures on all tasks.
description: Under review at journal
Supplemental Material - Neighborhood Built Environments and Health in Later Life: A Literature Review
Creators: name: Finlay, Jessica
name: Westrick, Ashly C.
name: Guzman, Viveka
name: Meltzer, Gabriella
Publisher: name: SAGE Journals
Year: 2023
Subjects: Endocrinology
Geriatrics and Gerontology
Public Health and Health Services not elsewhere classified

description: Supplemental Material for Neighborhood Built Environments and Health in Later Life: A Literature Review by Jessica Finlay, Ashly C. Westrick, Viveka Guzman, and Gabriella Meltzer in Journal of Aging and Health.
Additional file 7 of Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
Creators: name: Miao, Jia-xi
name: Xu, Jia-ping
name: Wang, Rui
name: Xu, Yu-xian
name: Xu, Feng
name: Wang, Chun-hua
name: Yu, Chao
name: Zhang, Dong-mei
name: Su, Jian-bin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 7: Table S5. Impact of body composition on outcomes of islet α- and β-cell functions according to multivariate linear regression analysis in women with T2D (n = 315).
On relativistic thermodynamics
Creators: name: Wallace, David
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: 'Relativistic thermodynamics' should be understood not as a generalization of a non-relativistic theory but as an application of a general thermodynamic framework, neutral as to spacetime setting and allowing arbitrary conserved quantities, to the specific case of relativity. That framework gives an unambiguous result as to the thermodynamics of relativistically moving systems (an answer coinciding with Einstein's, and Planck's, original results.) Thermodynamic temperature is unambiguously defined as rate of change of energy with entropy at constant momentum; that said, its operational significance is limited and other measures of energy/entropy covariance, which incorporate momentum transfer, are often more useful.
description: 22 pages; very substantially revised from previous version
sj-pdf-1-mrj-10.1177_00222437231195577 - Supplemental material for Correcting Regressor-Endogeneity Bias via Instrument-Free Joint Estimation Using Semiparametric Odds Ratio Models
Creators: name: Qian, Yi
name: Xie, Hui
Publisher: name: SAGE Journals
Year: 2023
Subjects: Hospitality Management

description: Supplemental material, sj-pdf-1-mrj-10.1177_00222437231195577 for Correcting Regressor-Endogeneity Bias via Instrument-Free Joint Estimation Using Semiparametric Odds Ratio Models by Yi Qian and Hui Xie in Journal of Marketing Research
Additional file 1 of The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation
Creators: name: Zhou, Shi-Qing
name: Feng, Ping
name: Ye, Ming-Liang
name: Huang, Sheng-Yan
name: He, Shi-Wei
name: Zhu, Xun-Hua
name: Chen, Jun
name: Zhang, Qun
name: Li, Ying-Qing
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Effect of acute stress on the expression of BDNF in the hippocampus of the Roman rats, a genetic model of stress-induced depression-like behaviour
Creators: name: Quartu, Marina
Publisher: name: Firenze University Press
Year: 2017
Subjects: Depression; BDNF; hippocampus; western blot; immunohistochemistry

description: The outbred Roman High- (RHA) and Roman Low-Avoidance (RLA) rats were psychogenetically selected for rapid vs. poor acquisition of active avoidance, respectively, and differ in many behavioural traits. Thus, RHA rats are impulsive, novelty seekers, and proactive copers, whereas RLA rats display behavioural traits that resemble some of the cardinal symptoms of depression (1). Beyond the monoamine hypothesis, compelling evidence suggests that mood disorders are characterized by reduced neuronal plasticity. Thus, it has been shown that exposure to stress and antidepressant treatments modulate the expression of neurotrophic factors, and that these changes show an anatomical specificity (2). To characterize the molecular and neuronal systems involved in the pathogenesis of stress-induced depression and in the mechanism of action of antidepressant treatments, we performed western blot (WB) and immunohistochemistry studies to assess the localization of the brain-derived neurotrophic factor (BDNF) in the hippocampus of RHA and RLA rats, both under basal conditions and after exposure to an acute stressor, i.e., the Forced Swim Test (FST). WB analyses showed that, under basal conditions, the relative levels of BDNF were lower in RLA vs. RHA rats, whereas, after FST, the relative levels of BDNF were markedly higher in the hippocampus of RLA vs. RHA rats. In brain tissue sections, BDNF-like immunoreactive material labeled neuronal cell bodies, proximal processes and varicose nerve fibers. Densitometric analysis used to compare immunostained brain sections from the two rat lines showed that, under basal conditions and upon FST, major differences were limited to the hippocampus proper, mostly to the CA3 and CA2 sectors, whereas the dentate gyrus (DG) showed no line-related differences. These results are at variance with previous studies showing that the expression of BDNF in the hippocampus is reduced in depressed patients and in rats exposed to stressors. In conclusion, the present study provides morphological evidence for an unexpected differential regional expression of BDNF in the hippocampus of RLA vs. RHA rats and supports the view that acute stress stimulates neuronal plasticity in genetic animal models of depression. This work was supported by grants from L.R. 07/2007, RAS project 2012.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Leadership and Organizational Performance of Public Universities in Kachin State
Creators: name: Nay Tun Aung
name: Zin Ko Ko
name: Nan Wai Linn
name: Yin Ko Ko
Publisher: name: gjrpublication
Year: 2024

description: Leadership and organizational performance are a valuable topic that has debated worldwide for ages. Every organization needed leaders for their survival during pandemic and crisis. Especially all of the business organizations required standards and norms to get better organizational performance among strong competitive industries. Moreover, higher education institutions face significant challenges because the educational environment is a changing environment. In Myanmar, National Education Law was enacted in 2014. Service quality of Myanmar higher education is developing every year. The development of higher education sector mainly depends on academic leadership. Academic leader is not enough to manage operations and hold specialized degrees but must develop people. Leadership and organizational performance of public universities in Kachin state is crucial subject matter because higher education institutions always produce future leaders and they offer people both expectation and dream.

This study examines the crucial role of academic leadership on organizational performance of public universities in Kachin State, Myanmar. The study focused on the variables, transformational leadership, transactional leadership and laissez- faire leadership and mediating effect of service quality on the relationship between leadership style and organizational performance in public universities in Kachin state.
Cholesteatoma affected incus bone surface shows unusual iron-rich crystals, microvesicles and altered bone turnover
Creators: name: Relucenti, Michela
name: Matassa, Roberto
name: Miglietta, Selenia
name: Battaglione, Ezio
name: Covelli, Edoardo
name: Barbara, Maurizio
name: Familiari, Giuseppe
Publisher: name: Firenze University Press
Year: 2017
Subjects: Cholesteatoma; scanning electron microscopy; microvesicle; crystals

description: Cholesteatoma is a noncancerous cystic lesion consisting in an abnormal growth of keratinizing squamous epithelium that invades the middle ear cavity. Due to its capacity of intracranial complications, cholesteatoma is cause of pediatric morbidity and death in countries with scarce hygiene and low possibility to access to advanced medical care (1). In order to understand cholesteatoma etiopathogenesis, we performed a SEM morphological analysis of 11 incus bones affected by cholesteatoma. Samples were fixed immediately upon recovery in 2.5% glutaraldehyde in PBS at 4°C for 48 h, then they were gently sonicated (to remove excess of keratinizing squamous epithelium, that would have prevented surface observation) and finally they were prepared with standard method for scanning electron microscopy observation. Five consecutive fields at 100X magnification aligned in 3 raws, the first one proximal and the last one distal to surgical removal point were analized. Images were obtained in secondary electron mode and in backscattering, bidimensional EDX analysis and mapping was also carried on. Incus bone surface analysis reveals the existence of an environment in which abnormal bone turnover takes place, in fact area of marked erosion were present together with areas of new bone formation. Resorbing bone surfaces with their characteristic lacunae were observed, resting surfaces (smooth and with collagen fibre bundles evident) were found and forming bone surface (collagen bundles in which calcium salts were just deposited) were also observed. Unusual flower-like apatite crystals rich in iron were uncovered in one sample. Iron presence may be due to cholesteatoma itself, being it made up of corneocytes that are iron-rich cells (2). Microvesicles of cellular origin, alone or clustered in groups or in about to fusing together, were found. Macrophages, lymphocytes osteoblast and osteoclast were observed in fully activated stage. The picture of these cell near to each other is the morphological representation of the complex cytochemical dialog existing among them. Taken all together our morphological results let us hypothesize that cholesteatoma creates an environment of chronic infection with peculiar biochemical characteristics that alters normal bone turnover on incus bone.This work was supported by grants from MIUR.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
sj-docx-2-msj-10.1177_13524585231213241 – Supplemental material for Modifying diet and exercise in multiple sclerosis (MoDEMS): A randomized controlled trial for behavioral weight loss in adults with multiple sclerosis and obesity
Creators: name: Bruce, Jared M
name: Cozart, Julia S
name: Shook, Robin P
name: Befort, Christie
name: Siengsukon, Catherine F
name: Simon, Stephen
name: Lynch, Sharon G
name: Mahmoud, Rola
name: Drees, Betty
name: Posson, Paige
name: Hibbing, Paul R
name: Huebner, Joanie
name: Bradish, Taylor
name: Robichaud, Jade
name: Bruce, Amanda S
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care

description: Supplemental material, sj-docx-2-msj-10.1177_13524585231213241 for Modifying diet and exercise in multiple sclerosis (MoDEMS): A randomized controlled trial for behavioral weight loss in adults with multiple sclerosis and obesity by Jared M Bruce, Julia S Cozart, Robin P Shook, Christie Befort, Catherine F Siengsukon, Stephen Simon, Sharon G Lynch, Rola Mahmoud, Betty Drees, Paige Posson, Paul R Hibbing, Joanie Huebner, Taylor Bradish, Jade Robichaud and Amanda S Bruce in Multiple Sclerosis Journal
The effectiveness of strengths based early intervention with young autistic children and their families
Creators: name: Thomas, Claudi
Publisher: name: The Open University
Year: 2025
Subjects: classificationCode: 420303
subject: Family care
classificationCode: 420318
subject: People with disability

description: Analysis of data to establish impact, and improve the effectiveness, of an early intervention programme offered by the Transforming Autism charity to young autistic children and their family and caregivers
Additional file 2 of The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation
Creators: name: Zhou, Shi-Qing
name: Feng, Ping
name: Ye, Ming-Liang
name: Huang, Sheng-Yan
name: He, Shi-Wei
name: Zhu, Xun-Hua
name: Chen, Jun
name: Zhang, Qun
name: Li, Ying-Qing
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Increased MG-63s invasion potential mediated by HFs
Creators: name: Salvatore, Viviana
name: Focaroli, Stefano
name: Mazzotti, Maria Carla
name: Falconi, Mirella
Publisher: name: Firenze University Press
Year: 2017
Subjects: Tumor microenvironment; cell invasion; co-culture

description: During a malignant transformation, the crosstalk between the stroma and the cancer cells is described as a growing network of physical and paracrine signals, and it seems to have a direct influence on the phenotypic, genetic and epigenetic changes that affect the cells (1). In order to invade and metastasize to distant tissues, cancer cells transform themselves via ECM, induce tumor angiogenesis as well as undergo proliferation, detachment, migration, and invasion through secretion of various tumor derived factors (2). In this study we decided to analyze morphological and molecular aspects due to the coexistence between tumor cells MG-63s and fibroblasts HFs, verifying in particular the ability of MG-63s of invasion and microenvironment modulation. Monolayers of co-cultured cells were morphologically analyzed in time-laps by HR-SEM microscopy and a trans-well migration assay was performed over 24 h, 48 h, 72 h, and 96 h. The expression of several proteins, focusing on those involved in cancer cell invasion, inflammatory responses, and angiogenesis (TNF alpha, IL-6, YKL-40, MMP-1, MMP-9, and VEGF) was validated by Western blotting analysis. The images in time-laps for HR - SEM showed that fibroblasts in contact with MG-63 lost their spatial orientation, while the MG-63 quickly reached the confluence advancing towards HF cells, invading their space and overlying them. The increased MG-63s invasion mediated by the coexistence with HFs was confirmed by invasion assays in transwell co-culture. The protein levels of TNF-alpha, IL-6, YKL-40 and VEGF confirmed that tumor cells can regulate the development of a “tumor-stroma” via the aberrant expression of growth factors in the stromal compartment. Our results showed how tumor-stroma interactions play a significant role in tumor development and progression.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Effects of methacrilyc thermosets coated with Silver-polysaccharide nanocomposite on HGFs adhesion in a S. mitis co-culture system
Creators: name: Sancilio, Silvia
name: Gallorini, Marialucia
name: Rapino, Monica
name: Di Valerio, Valentina
name: Marsich, Eleonora
name: Di Giulio, Mara
name: Cataldi, Amelia
name: Di Giacomo, Viviana
Publisher: name: Firenze University Press
Year: 2017
Subjects: Human gingival fibroblasts; co-culture; Chitlac-nAg

description: Silver based medical products have been proven to be effective in retarding and preventing bacterial growth, being silver reported to control infections since ancient times (1). In the field of dentistry, the use of silver ions/nanoparticles has been explored to counteract bacteria in resins and implants, as silver can destroy bacterial cell walls by reacting with the thiol groups (–SH) of proteins exposed to the extracellular portion of the bacterial membrane. Conversely, eukaryotic cells lack these exterior binding sites, so nanoparticles are supposed to interact with them only upon metal internalization (2). To reduce both bacterial adhesion to dental devices and cytotoxicity against eukaryotic cells, we coated BisGMA/TEGDMA methacrylic thermosets with a new material, Chitlac-nAg, formed by stabilized silver nanoparticles with a polyelectrolyte solution containing Chitlac. Here we analyzed the proliferative and adhesive ability of human gingival fibroblasts (HGFs) on BisGMA/TEGDMA thermosets uncoated and coated with AgNPs in a co-culture model system with Streptococcus mitis. After 48 h, HGFs well adhered onto both surfaces, while S. mitis cytotoxic response was higher in the presence of AgNPs coated thermosets. After 24 h thermosets coated with Chitlac as well as those coated with Chitlac-nAg exerted a minimal cytotoxic effect on HGFs, while after 48 h LDH release rised up to 20%. Moreover, the presence of S. mitis reduced this release mainly when HGFs adhered to Chitlac-nAg coated thermosets. The reduced secretion of collagen type I was significant in the presence of both surfaces even more when saliva is added. Integrin β1 localized closely to cell membranes onto Chitlac-nAg thermosets and PKC α translocated into nuclei. These data confirm that Chitlac-nAg thermosets have a promising utilization in the field of restorative dentistry exerting their antimicrobial activity due to AgNPs without cytotoxicity for eukaryotic cells.This work was supported by grants from MIUR FIRB 2010 and MIUR PRIN-2009.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Novel mechanisms of neuroprotective effects of Quercetin on human striatal neuroblasts
Creators: name: Sarchielli, Erica
name: Guarnieri, Giulia
name: Iorizzi, Maria
name: Lodi, Leda
name: Morelli, Annamaria
name: Sgambati, Eleonora
Publisher: name: Firenze University Press
Year: 2017
Subjects: Quercetin; human striatal neuroblasts; neuroprotection

description: Human striatal precursor (HSP) primary cell cultures were isolated from ganglionic eminence of 9-12 week old human fetuses and extensively characterized in vitro (1). Our studies demonstrated that these cultures consists of a mixed population of neural stem cells, neuronal-restricted progenitors and striatal neurons that express and are responsive to many trophic factors, as BDNF and FGF2, and possess an adaptive response to stress conditions as nutrient deprivation and hypoxia through mechanisms involving different factors and neurotrophins (1,2). In the last decades, several in vitro and in vivo studies have provided evidence for neuroprotective effects by Quercetin, a polyphenol widely present in nature, passively absorbed in the small intestine and able to traverse the blood brain barrier (3). However, the mechanisms through which Quercetin exerts its neuroprotective effects are not fully delucidated. Our study was aimed at investigating the effects of Quercetin on HSP cells and its contribution to cell survival in nutrient deprivation condition, obtained replacing culture medium with Phosphate Buffer Saline (PBS). Quercetin treatment significantly promoted cell survival and strongly decreased apoptosis induced by nutrient deprivation condition, as evaluated by MTT assay, Trypan Blue staining and western blot analysis of cell death and proliferation markers. Moreover, since the adhesive capacities of cells are essential for cell survival, we next analysed the expression of some adhesion molecules such as Pancadherin and Focal Adhesion Kinase; our results interestingly showed that PBS exposure determined a strong decrease in all the analysed adhesion molecules, while in presence of Quercetin the expression was significantly increased. Our results add new mechanicistic insights into the comprehension of neuroprotective action of Quercetin treatment, thus suggesting possible implications in sustaining striatal neuron survival during neurodegenerative disorders, such as Huntington Disease.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Supplemental Material - Data-Driven Precision Nutrition Improves Clinical Outcomes and Risk Scores for IBS, Depression, Anxiety, and T2D
Creators: name: Connell, Janelle
name: Toma, Ryan
name: Ho, Cleo Han-Chen
name: Shen, Nan
name: Moura, Pedro
name: Le, Tiep
name: Patridge, Eric
name: Antoine, Grant
name: Keiser, Hilary
name: Julian, Cristina
name: Naidoo, Uma
name: Tanton, Damon
name: Banavar, Guruduth
name: Vuyisich, Momchilo
Publisher: name: SAGE Journals
Year: 2023
Subjects: Nursing not elsewhere classified
Nutrition and Dietetics not elsewhere classified
Public Health and Health Services not elsewhere classified

description: Supplemental Material for Data-Driven Precision Nutrition Improves Clinical Outcomes and Risk Scores for IBS, Depression, Anxiety, and T2D by Janelle Connell, Ryan Toma, Cleo Han-Chen Ho, Nan Shen, Pedro Moura, Tiep Le, Eric Patridge, Grant Antoine, Hilary Keiser, Cristina Julian, Uma Naidoo, Damon Tanton, Guruduth Banavar, and Momchilo Vuyisich in American Journal of Lifestyle Medicine
Sulforaphane prevents oxidative stress and cell death in rat cardiomyocytes
Creators: name: Teti, Gabriella
name: Angeloni, Cristina
name: Malaguti, Marco
name: Barbalace, Maria Cristina
name: Hrelia, Silvana
name: Falconi, Mirella
Publisher: name: Firenze University Press
Year: 2017
Subjects: Cardiomyocytes; sulforaphane; oxidative stress; cardiovascular diseases

description: Cardiovascular diseases (CVDs) are the major cause of death in developed countries. Oxidative stress plays a major role in the pathophysiology of cardiac disorders. Several studies have highlighted the cardinal role played by the overproduction of reactive oxygen species in the pathogenesis of ischemic myocardial damage and consequent cardiac dysfunction. Sulforaphane (SF) is a molecule within the isothiocyanate (ITC) group of organosulfur compound commonly found in cruciferous vegetables. It is reported to be capable of stimulating cellular antioxidant defenses and inducing phase 2 detoxifying enzymes, which can protect cells against oxidative damage. Although SF is known for its anticancer benefits, its role in cardioprotection is emerging. The aim of this study was to investigate the effects of SF in preventing cell damage induced by oxidative stress. Primary rat cardiomyocytes were exposed to different concentrations of SF for 24 h and subsequently treated with H2O2 to induce oxidative stress. Cell viability, and the expression of oxidative stress markers were studied. A transmission electron microscopy (TEM) analysis was carried out to evaluate the effect of SF on cell morphology. Results showed an higher cell viability and a lower level of oxidative stress in cells pre-treated with SF before peroxide exposure in respect to H2O2 treated cardiomyocytes. TEM analysis showed a well preserved morphology in cells pre-treated with SF before H2O2. These findings demonstrate that sulforaphane prevents H2O2 - induced oxidative stress and cell death in rat cardiomyocytes, suggesting a potential protective role of SF in CVDs
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Supplemental Material - Social and Neighborhood Context Moderates the Associations Between Processing Speed and Driving Mobility: A 10-year Analysis of the ACTIVE Study
Creators: name: Rebok, George W.
name: Clay, Olivio J.
name: Thorpe, Roland J.
name: Willis, Sherry L.
name: Pope, Caitlin N.
name: Wheeler, Katie M.
name: Bell, Tyler R.
name: Carroll, Brooke E.
name: Ross, Lesley A.
name: Crowe, Michael
name: Black, Shelia R.
name: Ball, Karlene K.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Endocrinology
Geriatrics and Gerontology
Public Health and Health Services not elsewhere classified

description: Supplemental Material for Social and Neighborhood Context Moderates the Associations Between Processing Speed and Driving Mobility: A 10-year Analysis of the ACTIVE Study by Caitlin N. Pope, Katie M. Wheeler, Tyler R. Bell, Brooke E. Carroll, Lesley A. Ross, Michael Crowe, Shelia R. Black, Olivio J. Clay, and Karlene K. Ball in Journal of Aging and Health
Implications for the non-Gaussianity of curvature perturbation from pulsar timing arrays
Creators: name: Liu, Lang
name: Chen, Zu-Cheng
name: Huang, Qing-Guo
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The recently released data by pulsar timing array (PTA) collaborations present strong evidence for a stochastic signal consistent with a gravitational-wave background. Assuming this signal originates from scalar-induced gravitational waves, we jointly use the PTA data from the NANOGrav 15-yr data set, PPTA DR3, and EPTA DR2 to probe the small-scale non-Gaussianity. We put the first-ever constraint on the non-Gaussianity parameter, finding $|F_\mathrm{NL}|\lesssim 13.9$ for a lognormal power spectrum of the curvature perturbations. Furthermore, we obtain $-13.9 \lesssim F_\mathrm{NL}\lesssim -0.1$ to prevent excessive production of primordial black holes. Moreover, the multi-band observations with the space-borne gravitational-wave detectors, such as LISA/Taiji/TianQin, will provide a complementary investigation of primordial non-Gaussianity. Our findings pave the way to constrain inflation models with PTA data.
description: 8 pages, 2 figures, 1 table; Refs added; Supplementary Material added; Accepted by PRD as a Letter
Supplemental Material - Prognostic Implications of Changes in Total Physiological Atherosclerotic Burden in Patients With Coronary Artery Disease—A Serial QFR Study
Creators: name: Chu, Jiapeng
name: Yuan, Deqiang
name: Lai, Yan
name: Ye, Wen
name: Liu, Lei
name: Lin, Hao
name: Ping, Fan
name: Zhu, Guoqi
name: Chen, Fei
name: Yao, Yian
name: Yan, Wenwen
name: Liu, Xuebo
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cardiology

description: Supplemental Material for Prognostic Implications of Changes in Total Physiological Atherosclerotic Burden in Patients With Coronary Artery Disease—A Serial QFR Study by Jiapeng Chu, Deqiang Yuan, Yan Lai, Wen Ye, Lei Liu, Hao Lin, Fan Ping, Guoqi Zhu, Fei Chen, Yian Yao, Wenwen Yan, and Xuebo Liu in Angiology
title: Frans de Neve, ein flämischer Maler im 17. Jahrhundert auf Wanderschaft in Süd- und Mitteleuropa
Creators: name: Stillfried, Silvia
Year: 2008

description: Bisher gibt es keine ausführliche Dokumentation über Leben und Werk des Frans de Neve. Ein Geburtsdatum von 1606 und eine weitere Eintragung in der St. Lukasgilde von Antwerpen im Jahre 1690/91 werfen die Frage auf, ob dieser Künstler ein hohes Alter erreicht haben könnte oder ob es sich um zwei oder gar drei Maler gleichen Namens handelt. In der jüngeren Forschung vermutet man zwar zwei Künstler, aber dies konnte bis dato nicht belegt werden. Diese Arbeit ist der Versuch, die offenen Fragen zu klären und ein Werkverzeichnis zu erstellen, das sich, ohne Anspruch auf Vollständigkeit, auf die Ölbilder des Künstlers in Süd- und Mitteleuropa beschränkt. Die Aufarbeitung der Zeichen- und Druckgraphik muss weiterer Forschung vorbehalten bleiben. Die Recherchen haben ergeben, dass unter dem Namen Frans de Neve zwei Künstler, nämlich Vater und Sohn als Maler tätig waren. Der Ältere wurde 1606 in Antwerpen geboren, arbeitete vorwiegend in seiner Heimatstadt und starb um 1681 daselbst oder in Brüssel. Sein Sohn, Frans II, wurde 1632 in Antwerpen geboren und ist in den 1660er Jahren in Rom nachweisbar. Er war Mitglied der dortigen Künstlervereinigung „Bentveughels“ mit dem Bentnamen „Bloosaerken“. Von ca. 1669 bis 1689 hielt er sich in Mitteleuropa auf und malte vorwiegend Altarbilder für den Erzbischof von Salzburg, den Fürstbischof von Passau und die großen Benediktinerstifte Kremsmünster, Garsten und Admont. Für Karl Eusebius von Liechtenstein, ebenfalls ein Auftraggeber, war Frans II auch als Kunsthändler und Restaurator tätig. Um 1690 kehrte der Maler in seine Heimatstadt zurück und wird in der dortigen St. Lukasgilde genannt. Frans II vertritt in seinen Altarbildern einen Mischstil aus flämischen, venezianischen und klassisch-römischen Vorbildern wie Rubens, Raphael, Tizian, Tintoretto, Pietro da Cortona aber auch Poussin. Hervorzuheben sind der flämische Oberflächenrealismus, eine Farbigkeit in differenzierten Braun- und Rottönen, die gegen die 1680er Jahre stärker ins Rötliche übergeht und gegen Ende seines Aufenthaltes in Mitteleuropa ins Süßliche mit vermehrten Rosatönen wechselt. Gelegentlich tauchen Mythologien und andere Bildgattungen im Kunsthandel auf. Die Kolorierung der Ölgemälde wie auch seine Porträtkunst, die hauptsächlich in Kupferstichen erhalten ist, wurde von den Zeitgenossen hoch geschätzt. Weiters ist eine große Anzahl kleinformatiger, signierter Landschaftsbilder fast ausschließlich in Kupferstichen tradiert, die von Giovanni Giacomo de Rossi alla Pace in den 1660er Jahren in Rom gestochen wurden. Sie fanden weite Verbreitung und waren bereits in frühen Sammlungen anzutreffen. Der Maler gehörte zu jenen auswärtigen Wanderkünstlern, deren Vorherrschaft in Mitteleuropa ab den 1680er Jahren langsam zu Ende ging und an deren Stelle dann zunehmend einheimische Künstler traten. Er starb nach 1704.
Role of melatonin in HT22 cells challenged with serum deprivation
Creators: name: Di Sario, Gianna
name: Cesarini, Erica
name: Canonico, Barbara
name: Gabrielli, Sara
name: Zamai, Loris
name: Papa, Stefano
name: Luchetti, Francesca
Publisher: name: Firenze University Press
Year: 2017
Subjects: Melatonin; HT22; serum deprivation

description: In vitro serum deprivation (SD) is one model for investigating the molecular mechanisms underlying apoptosis as well as autophagy, which generally function as defense strategies upon cell injury by eliminating damaged organelles [1]. Furthermore, SD injury in vitro is widely used to mimic the ischemic environment [2]. In serum deprived conditions, cells show different parameters of apoptosis and autophagy. Melatonin (MLT), a lipophilic indole secreted by pineal and non-pineal cells, is a well-known potent free radical scavenger acting as neuroprotective molecule that prevents apoptotic cell death in several models of neurodegenerative diseases. In the present study we investigated the neuroprotective effects of MLT during SD condition on mouse hippocampal HT22 cells, considering that intracellular ROS are usually linked to autophagy and apoptosis. To explore potential effects of combining SD with melatonin we studied clonogenic survival of HT22 cells. Clonogenic assay demonstrated a significative (p< 0.01) reduction of HT22 total cell numbers challenged for 24h with SD, whereas the pre-treatment with 200nM of MLT for 24hr noticeably reduced this effect of about 30%. In HT22 starved cells the percentage of MitoTracker Red (MTR) positive cells doubled (P< 0.05) if compared to the control condition, suggesting that SD induced a remodelling of mitochondrial network. It is noteworthy that MLT pre-treatment produced a MTR positivity similar to that of controls. We next investigated whether melatonin was able to influence the autophagic pathway. Autophagy was detected by measuring the aggregation of LC3B protein coupled to green fluorescence protein (GFP). Confocal images show that SD induced an increase in the GFP-LC3 puncta, whereas the melatonin treatment reduces these aggregations. Taken together, our results suggest that MLT treatment may play protective roles against cellular modifications induced by SD treatment in HT22 cells.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
sj-docx-4-hss-10.1177_15563316231213367 – Supplemental material for Innovations in Total Hip and Knee Arthroplasty Episodes of Care: Transitioning from Inpatient to Ambulatory Care
Creators: name: Tuohy, Sharlynn
name: Ast, Michael P.
name: Quinlan, Patricia
name: Titmuss, Matthew
name: Edwards, Danielle
Publisher: name: SAGE Journals
Year: 2023
Subjects: Surgery

description: Supplemental material, sj-docx-4-hss-10.1177_15563316231213367 for Innovations in Total Hip and Knee Arthroplasty Episodes of Care: Transitioning from Inpatient to Ambulatory Care by Sharlynn Tuohy, Michael P. Ast, Patricia Quinlan, Matthew Titmuss and Danielle Edwards in HSS Journal®
sj-pdf-1-jso-10.1177_23971983231209807 – Supplemental material for Deficiency and altered phenotype of mucosal-associated invariant T cells in systemic sclerosis
Creators: name: Lesturgie-Talarek, Manon
name: Gonzalez, Virginie
name: Beaudoin, Lucie
name: Frantz, Camelia
name: Sénot, Noémie
name: Gouda, Zouriatou
name: Rousseau, Camille
name: Avouac, Jérôme
name: Lehuen, Agnès
name: Allanore, Yannick
Publisher: name: SAGE Journals
Year: 2023
Subjects: Rheumatology and Arthritis

description: Supplemental material, sj-pdf-1-jso-10.1177_23971983231209807 for Deficiency and altered phenotype of mucosal-associated invariant T cells in systemic sclerosis by Manon Lesturgie-Talarek, Virginie Gonzalez, Lucie Beaudoin, Camelia Frantz, Noémie Sénot, Zouriatou Gouda, Camille Rousseau, Jérôme Avouac, Agnès Lehuen and Yannick Allanore in Journal of Scleroderma and Related Disorders
Sediment Transport Modelling Using Dynamic (Dis)Connectivity Prediction for a Bedrock Controlled Catchment
Creators: name: Mahoney, David Tyler
Publisher: name: University of Kentucky Libraries
Year: 2017
Subjects: subject: Civil Engineering
subject: FOS: Civil engineering
subject: Environmental Engineering
subject: FOS: Environmental engineering

description: The (dis)connectivity of sediment, defined as the detachment and transport of sediment from source to sink between geomorphic zones, is a major control on sediment transport rates but has seldom taken precedence in sediment transport models that focus on assessment of sediment impacts on water supply. A watershed-scale sediment transport model was formulated that incorporates sediment (dis)connectivity knowledge and subroutines and predicts sediment flux through coupling with an excessive shear stress erosion equation. The intersecting probabilities of sediment supply, detachment, transport, and (dis)connectivity produce the probability of sediment connectivity for a watershed or region of a watershed. The integration of the net watershed probability of sediment connectivity yields an estimate of the active watershed area in terms of sediment transport when multiplied times the entire watershed area. The sediment transport model was tested for a bedrock controlled catchment in the Southeastern United States for which extensive historic water and sediment flux data was available. It is expected that the model presented here can be used as a tool to assess the regional impacts of natural and anthropogenic sources of (dis)connectivity on sedimentation rates that lead to problems such as reservoir sedimentation and water quality degradation.
Biliary tree stem cells are involved in the pathogenesis of primary sclerosing cholangitis
Creators: name: Carpino, Guido
name: Franchitto, Antonio
name: Cardinale, Vincenzo
name: Alvaro, Domenico
name: Karlsen, Tom H.
name: Gaudio, Eugenio
Publisher: name: Firenze University Press
Year: 2017
Subjects: Stem cells; biliary tree; hedgehog; liver cirrhosis

description: Biliary tree stem cells (BTSCs) are multipotent stem cells located in peribiliary glands (PBGs) of extrahepatic and large intrahepatic bile ducts (1). Primary sclerosing cholangitis (PSC) is characterised by fibro-stenosing strictures involving extrahepatic and/or large intrahepatic bile ducts. Mechanisms leading to bile duct injury are poorly understood (2). Our aims are to study the role of BTSC in the pathogenesis of biliary fibrosis in PSC. Specimens containing extrahepatic or large intrahepatic bile ducts were obtained from normal liver (n=6), liver explants from patients with PSC (n=11), and primary biliary cirrhosis (n=6). Specimens were processed for histology, immunohistochemistry and immunofluorescence. In PSC samples, progressive hyperplasia and mucinous metaplasia of PBGs were observed in large ducts with fibrosis, but not in inflamed ducts without fibrosis. PBG hyperplasia was associated with progressive biliary fibrosis and the occurrence of dysplastic lesions. Hyperplasia of PBGs was determined by the expansion of biliary tree stem cells, which sprouted towards the surface epithelium. In PSC, PBGs and myofibroblasts displayed enhanced expression of Hedgehog pathway components. PBGs in ducts with onion skin-like fibrosis expressed epithelial-to-mesenchymal transition traits associated with components of Hedgehog pathway, markers of senescence and autophagy. The biliary tree stem cell compartment is activated in PSC, its activation contributes to biliary fibrosis, and is sustained by the Hedgehog pathway. Our findings suggest a key role for peribiliary glands in the progression of bile duct lesions in PSC and could explain the associated high risk of cholangiocarcinoma. This work was supported by grants from MIUR FIRB 2010 and MIUR PRIN-2009.
description: Italian Journal of Anatomy and Embryology, Vol. 121, No. 1 (Supplement) 2016
Additional file 3 of The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation
Creators: name: Zhou, Shi-Qing
name: Feng, Ping
name: Ye, Ming-Liang
name: Huang, Sheng-Yan
name: He, Shi-Wei
name: Zhu, Xun-Hua
name: Chen, Jun
name: Zhang, Qun
name: Li, Ying-Qing
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 3
sj-docx-1-fac-10.1177_27325016231212564 – Supplemental material for A Scoping Review of Adjuvant Perioperative Therapies for Primary Cleft Lip Repair
Creators: name: Lem, Melinda
name: T Pham, Jason
name: Arora, Jagmeet
name: Trivedi, Shivang
name: Arowojolu, Omotayo
name: Castro, Ruben
name: Mocharnuk, Joseph
name: Vyas, Raj
name: Pfaff, Miles J.
Publisher: name: SAGE Journals
Year: 2023
Subjects: Surgery

description: Supplemental material, sj-docx-1-fac-10.1177_27325016231212564 for A Scoping Review of Adjuvant Perioperative Therapies for Primary Cleft Lip Repair by Melinda Lem, Jason T Pham, Jagmeet Arora, Shivang Trivedi, Omotayo Arowojolu, Ruben Castro, Joseph Mocharnuk, Raj Vyas and Miles J. Pfaff in FACE
sj-docx-1-dhj-10.1177_20552076231207577 - Supplemental material for Challenges in e-Health: The effect of digitalisation of frequency voiding charts on compliance in paediatric patients. Randomised controlled trial comparing digital and versus paper frequency voiding charts
Creators: name: de Wall, Liesbeth L
name: Kragt, Elisabeth AM
name: Van De Wetering, Eline HM
name: Cobussen-Boekhorst, Johanna GL
name: Mantel-van Stel, Joyce
name: Kortmann, Barbara BM
name: Feitz, Wout F
name: Bootsma-Robroeks, Charlotte MHHT
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Nursing not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Aged Health Care
subject: Public Health and Health Services not elsewhere classified
subject: Engineering not elsewhere classified
subject: Anthropology
subject: FOS: Sociology
subject: Cultural Studies not elsewhere classified
subject: Information and Computing Sciences not elsewhere classified
subject: Organisation and Management Theory
subject: Science Policy
subject: Social Policy
subject: Sociology

description: Supplemental material, sj-docx-1-dhj-10.1177_20552076231207577 for Challenges in e-Health: The effect of digitalisation of frequency voiding charts on compliance in paediatric patients. Randomised controlled trial comparing digital and versus paper frequency voiding charts by Liesbeth L de Wall, Elisabeth AM Kragt, Eline HM Van De Wetering, Johanna GL Cobussen-Boekhorst, Joyce Mantel-van Stel, Barbara BM Kortmann, Wout F Feitz and Charlotte MHHT Bootsma-Robroeks in DIGITAL HEALTH
sj-docx-1-tva-10.1177_15248380231188068 – Supplemental material for The Impacts of Intimate Partner Violence on Postpartum Depression: An Updated Meta-Analysis
Creators: name: Wei, Xinyi
name: Wang, Weiwei
name: Law, Yik Wa
name: Zhang, Huiping
Publisher: name: SAGE Journals
Year: 2023
Subjects: Criminology not elsewhere classified

description: Supplemental material, sj-docx-1-tva-10.1177_15248380231188068 for The Impacts of Intimate Partner Violence on Postpartum Depression: An Updated Meta-Analysis by Xinyi Wei, Weiwei Wang, Yik Wa Law and Huiping Zhang in Trauma, Violence, & Abuse
sj-docx-1-aan-10.1177_02184923231187842 - Supplemental material for Coronary bronchial fistula – A rare incidental finding
Creators: name: Goswami, Sourabh
name: Deora, Surender
name: Rajagopal, Rengarajan
name: Sharma, Smily
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cardiology

description: Supplemental material, sj-docx-1-aan-10.1177_02184923231187842 for Coronary bronchial fistula – A rare incidental finding by Sourabh Goswami, Surender Deora, Rengarajan Rajagopal and Smily Sharma in Asian Cardiovascular and Thoracic Annals
sj-docx-1-jiv-10.1177_08862605231181377 – Supplemental material for Psychological Factors Linked to Intimate Partner Violence and Childhood Maltreatment: On Dissociation as a Possible Bridge Symptom
Creators: name: Krause-Utz, Annegret
name: Černáková, Romana
name: Hoogenboom, William
name: Schulze, Anna
name: Büttner, Sarah
name: Demirelli, Zeynep
name: Mouthaan, Joanne
name: van Schie, Charlotte C.
name: Garnefski, Nadia
name: Kraaij, Vivian
Publisher: name: SAGE Journals
Year: 2023
Subjects: Criminology not elsewhere classified

description: Supplemental material, sj-docx-1-jiv-10.1177_08862605231181377 for Psychological Factors Linked to Intimate Partner Violence and Childhood Maltreatment: On Dissociation as a Possible Bridge Symptom by Annegret Krause-Utz, Romana Černáková, William Hoogenboom, Anna Schulze, Sarah Büttner, Zeynep Demirelli, Joanne Mouthaan, Charlotte C. van Schie, Nadia Garnefski and Vivian Kraaij in Journal of Interpersonal Violence
sj-docx-3-rsh-10.1177_17579139231185004 – Supplemental material for We care but we’re not carers: perceptions and experiences of social prescribing in a UK national community organisation
Creators: name: Porter, B
name: Wood, C
name: Belderson, P
name: Manning, C
name: Meadows, R
name: Sanderson, K
name: Hanson, S
Publisher: name: SAGE Journals
Year: 2023
Subjects: Health and Community Services
Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-3-rsh-10.1177_17579139231185004 for We care but we’re not carers: perceptions and experiences of social prescribing in a UK national community organisation by B Porter, C Wood, P Belderson, C Manning, R Meadows, K Sanderson and S Hanson in Perspectives in Public Health
sj-docx-2-ctc-10.1177_25152564231211976 - Supplemental material for Phylogenetic and Structural Analyses of VPS13 Proteins in Archaeplastida Reveal Their Complex Evolutionary History in Viridiplantae
Creators: name: Leterme, Sébastien
name: Bastien, Olivier
name: Aiese Cigliano, Riccardo
name: Amato, Alberto
name: Michaud, Morgane
Publisher: name: SAGE Journals
Year: 2023
Subjects: Cell Biology

description: Supplemental material, sj-docx-2-ctc-10.1177_25152564231211976 for Phylogenetic and Structural Analyses of VPS13 Proteins in Archaeplastida Reveal Their Complex Evolutionary History in Viridiplantae by Sébastien Leterme, Olivier Bastien, Riccardo Aiese Cigliano, Alberto Amato and Morgane Michaud in Contact
Additional file 1 of mosGILT controls innate immunity and germ cell development in Anopheles gambiae
Creators: name: Arora, Gunjan
name: Tang, Xiaotian
name: Cui, Yingjun
name: Yang, Jing
name: Chuang, Yu-Min
name: Joshi, Jayadev
name: Sajid, Andaleeb
name: Dong, Yuemei
name: Cresswell, Peter
name: Dimopoulos, George
name: Fikrig, Erol
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Supplementary Figure 1. Distribution of Raw counts in all Anopheles samples. Supplementary Figure 2. Key statistics of Ovary samples. Supplementary Figure 3. Key statistics of whole-body samples. Supplementary Figure 4. Key statistics of Fatbody samples. Supplementary Figure 5. Pathway enrichment analysis using the g:Profiler online tool. Table provides comprehensive information related to the selected term, including the data source, term ID, term name, and corresponding p-value. Abbreviations: GO:BP (Gene Ontology: Biological Process); GO:CC (GO: Cellular Component); GO:MF (GO: Molecular Function). Supplementary Figure 6. Protein-Protein Interaction (PPI) network: The interaction Network of DEGs in the Ovary of mosGILTnull mosquitoes was created using the STRING database and imported into Cytoscape. The k clustering method was used to identify clusters and key nodes in this network.
Supplemental Material - Preparation of cellulose-based composite hydrogels for the removal of methylene blue
Creators: name: Aymara, Lizbeth
name: Herrera, Nora Gabriela
name: Lezama, Hélmer Helí
name: Villacrés, Nelson Adrián
Publisher: name: SAGE Journals
Year: 2023
Subjects: Materials Engineering not elsewhere classified

description: Supplemental Material for Preparation of cellulose-based composite hydrogels for the removal of methylene blue by Lizbeth Aymara, Nora Gabriela Herrera, Hélmer Helí Lezama and Nelson Adrián Villacrés in Polymers from Renewable Resources