cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The effect of dose reduction of CDK4/6 inhibitors on survival in postmenopausal HR+ HER2-negative metastatic breast cancer
Creators: name: Ceylan, Furkan
name: Efil, Safa Can
name: Sener, Didem
name: Tenekeci, Ates Kutay
name: Bilgin, Burak
name: Yücel, Şebnem
name: Ceylan, Eren Göktuğ
name: Hızal, Mutlu
name: Şendur, Mehmet Ali Nahit
name: Akıncı, Muhammed Bülent
name: Bal, Öznur
name: Yalçın, Bülent
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: This study aimed to evaluate the effect of dose reduction of CDK4/6 inhibitors on survival outcomes in postmenopausal patients with HR+ HER2-negative metastatic breast cancer (mBC). A retrospective cohort study was conducted involving 164 postmenopausal patients with HR+ HER2-negative mBC who received CDK4/6 inhibitors between 2021 and 2024. Clinical parameters were systematically analyzed. Progression-free survival (PFS) and overall survival (OS) were evaluated based on dose reduction status. Survival outcomes were estimated using the Kaplan-Meier method, and independent prognostic factors were identified through multivariate Cox regression analysis. The median age was 61 years, with a median follow-up of 23.5 months. The median PFS was 23.3 months, while median OS was not reached. Dose reduction occurred in 45 patients (27%), who exhibited significantly worse survival (PFS HR: 1.67, 95% CI: 1.02–2.72, p = 0.042; OS HR: 2.54, 95% CI: 1.34–4.83, p = 0.004). Dose reduction and liver metastases were independent risk factors for shorter PFS and OS, while treatment in later lines was associated with shorter PFS. Dose reductions in CDK4/6 inhibitors were associated with worse survival outcomes in postmenopausal HR+ HER2− mBC patients. Future biomarker-driven studies are needed to guide personalized dose adjustments and optimize treatment efficacy.
Suppression of colonization of the pathogenic strain and induction of resistance in tomato are involved in the biocontrol of bacterial wilt by using a phenotypic conversion mutant of Ralstonia pseudosolanacearum
Creators: name: Nakahara, Hiroki
name: Matsusaki, Hiromi
name: Mori, Taro
name: Kondo, Kensuke
name: Matsuzoe, Naotaka
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Ralstonia pseudosolanacearum causes bacterial wilt in plants and undergoes spontaneous phenotypic conversion (PC) from a wild-type pathogenic to a non-pathogenic form. Pre-inoculation of plants with PC mutants suppressed bacterial wilt after challenge with pathogenic strains. In this study, we investigated the colonization of pathogenic strains and PC mutants and induction of disease defense response in tomato plants as the mechanisms of biological control against bacterial wilt in plants by the PC mutants. We created a PC mutant labelled with a red fluorescent protein gene (DsRed2) and a pathogenic strain labelled with a green fluorescent protein gene (gfp) and observed the colonization of both strains in roots under a fluorescence microscope. In plants with disease suppressed, the PC mutants colonized the roots at a high density, and colonization of pathogenic strains was suppressed. Conversely, in plants in which the disease was not suppressed, the colonization of PC mutants in the roots was low, and the colonization of pathogenic strains could not be suppressed. In tomato plants inoculated with the PC mutant, the expression levels of pathogenesis-related (PR) protein genes PR-2b and PR-3a were significantly increased in both the roots and leaves compared to those in the control plants. However, several gene expressions including PR-1, PR-2a, PR-4, PR-5, and defense-related enzymes induced by inoculation with PC mutant indicated contrasting patterns in leaves and roots. These results suggested that the biocontrol of bacterial wilt by PC mutant is related to the suppression of colonization of pathogenic strains and induction of resistance in plants.
TV_BESMIN 2025 cruise,Thalassa R/V
Creators: name: Benoit, LOUBRIEU
name: Javier, ESCARTIN
Publisher: name: Sismer
Year: 2025

description: Initiative « Valorisation bathymétrique des transits de la flotte océanographique » L'acquisition de données bathymétriques sur ce transit est à l'initiative d'un groupe de géologues et géophysiciens , en concertation avec la Flotte Océanographique Française. L'objectif global de cette initiative est de généraliser l'acquisition de données de sondeurs multifaisceaux sur les transits des navires de la flotte, en vue de a) compléter les couvertures bathymétriques existantes à moyenne et haute résolution et contribuer à la cartographie bathymétrique globale des océans, b) établir un protocole d'acquisition et traitement des données des transits valorisées, et c) faciliter les travaux de recherche à travers le partage publique des données acquises lors de ces transits. Les données sont destinées à un usage de cartographie moyenne résolution (modèle numérique de terrain au pas de grille d'une centaine de mètres). L'acquisition de données se fait dans un mode contraint : - la vitesse du navire est celle fixée par le transit, sans ajustement vis-à-vis de la qualité des données ou leur résolution. - le sondeur multifaisceaux est placé dans un mode automatique. L'acquisition n'est pas nécessairement suivie en continu par un opérateur spécialisé. - les profils de célérité utilisés pour l'acquisition des données et le calcul des sondes sont établis à partir de tables globales, sans mesure in-situ de température et salinité lors de l'acquisition (de type sondes de température). Les données sont pré-traitées et validées et sont destinées à être mise à disposition à court terme dans la base de données des navires océanographiques Sismer. L'acquisition est limitée aux eaux internationales, pour lesquelles aucune demande d'autorisation n'est nécessaire.
Appendix_A – Supplemental material for Influence of increased body mass index on orthodontic tooth movement and related parameters in children and adolescents: A systematic review of longitudinal controlled clinical studies
Creators: name: Michelogiannakis, Dimitrios
name: P Emile Rossouw
name: Junad Khan
name: Zohaib Akram
name: Menenakos, Evangelos
name: Javed, Fawad
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, Appendix_A for Influence of increased body mass index on orthodontic tooth movement and related parameters in children and adolescents: A systematic review of longitudinal controlled clinical studies by Dimitrios Michelogiannakis, P Emile Rossouw, Junad Khan, Zohaib Akram, Evangelos Menenakos and Fawad Javed in Journal of Orthodontics
Additional file 3 of Forensic age assessment of late-term bovine fetuses
Creators: name: Agerholm, Jørgen Steen
name: Dahl, Maria
name: Herskin, Mette
name: Nielsen, Søren Saxmose
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Additional file 3: Regression of body weight at birth on gestation length (GL), parity and sex of 2,737 neonatal liveborn Holstein singletons. Model fit: R2=0.27 [95% confidence interval: 0.25–0.30].
Additional file 1 of Detection of reed using cnn method and analysis of the dry reed (phragmites australis) for a sustainable lake area
Creators: name: Obreja, Cristian Dragos
name: Buruiana, Daniela Laura
name: Mereuta, Elena
name: Muresan, Alina
name: Ceoromila, Alina Mihaela
name: Ghisman, Viorica
name: Axente, Roxana Elena
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Additional file 1: Figure S1: EDX spectra – qualitative chemical analysis of the analysed reed samples: a) and b) control reed (epidermis and cross-section); c) and d) reed maintained in water (epidermis and cross section). Figure S2: EDX mapping of the analysed reed samples.
KICHIK MAKTAB YOSHIDAGI O'QUVCHILARNING PSIXOLOGIK JARAYONLARI VA  XUSUSIYATLARINI  SHAKLLANISHI
Creators: name: Dilmurodova, Zilola
Publisher: name: Zenodo
Year: 2024

description: Ushbu mаqоlаdа kichik maktab yoshidagi o‘quvchilarning psixologik jarayonlari va xususiyatlarini shakllanishi, ularda uсhrаydigаn qоbiliyаtlаr, bola qobiliyatini kichik maktab yoshidagidayoq o'rganish nima uchun muhimligi  о`rgаnib сhiqilаdi.
Transformation of a cellular skyrmion to polyomino-like structures
Creators: name: Xia, Jing
name: Zhang, Xichao
name: Zhou, Yan
name: Liu, Xiaoxi
name: Zhao, Guoping
name: Mochizuki, Masahito
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Topological spin structures with transformable shapes may have potential implications on data storage and computation. Here, we demonstrate that a square cellular skyrmion on an artificial grid pinning pattern can be manipulated by programmed current pulses. We find that parallel short pulses could result in the elongation of the skyrmion mainly in the current direction, while parallel long pulses are able to induce the elongation in the direction perpendicular to the current due to the intrinsic skyrmion Hall effect. Consequently, a programmed sequence of parallel pulses could lead to the transformation of the skyrmion to I-, L-, and Z-shaped polyomino-like structures without affecting the topological charge. In addition, we find that orthogonal pulses could lead to the transformation to more complex polyomino-like structures, including the T-shaped and irregular ones. Particularly, when a small T-shaped structure is formed, the topological charge of the system is found to be non-integer due to incomplete compensation of local topological charge densities; however, the T-shaped structure is stable on the attractive pinning pattern. Our results offer an effective way to create polyomino-like spin structures toward functional applications.
description: 7 pages, 5 figures
Supplemental methods from Opsin gene expression plasticity and spectral sensitivity in male damselflies could mediate female colour morph detection
Creators: name: Roberts, Natalie S
name: Svensson, Erik I
name: Liénard, Marjorie A.
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Detailed methodology for opsin heterologous expression, mutagenesis, homology modeling, quantitive PCR analysis, visual modeling, and additional details on statistical analyses
title: Social vocalizations indicate behavioural type in Glossophagine bats
Creators: name: Schabacker, Theresa
name: Castiglione, Raffaella
name: Snijders, Lysanne
name: Knörnschild, Mirjam
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: animal personality
subject: communication
subject: Glossophaga bats
subject: consistent between-individual differences
subject: vocalizations
subject: behavioural syndrome
classificationCode: 570
subject: Biowissenschaften; Biologie

description: Vocalizations play a crucial role in the social systems of many animals and may inadvertently reveal behavioural characteristics of the sender. Bats, the second largest mammalian order, rely extensively on vocalizations owing to their nocturnal lifestyle and complex social systems, making them ideal for studying links between vocalizations and consistent behavioural traits. In this study, we developed a new testing regime to investigate whether consistent individual vocalization differences in nectarivorous bats are associated with specific behavioural types. We exposed 60 wild, male Glossophaga soricina handleyi bats to novel and risky stressors and assessed their behavioural and vocal responses. Proactive, exploratory and bold bats were more likely to produce social calls, and among the vocalizing bats, more agitated bats produced higher numbers of social calls. We thus show that bat vocalization behaviour can be indicative of a certain behavioural type, potentially allowing conspecifics to assess personalities from a distance, which in turn could impact subsequent social interactions, group dynamics and reproductive success. Our results, in combination with previous findings in birds, suggest that advertent or inadvertent long-distance broadcasting of personality may be widespread, thus opening up new exciting questions about the links between vocalizations and sociality.
Supplemental tables and figures from Opsin gene expression plasticity and spectral sensitivity in male damselflies could mediate female colour morph detection
Creators: name: Roberts, Natalie S
name: Svensson, Erik I
name: Liénard, Marjorie A.
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified

description: Supplemental tables and figures referenced in the main text
title: Role of Tailored Timing and Frequency Prompts on the Efficacy of an Internet-Delivered Stress Recovery Intervention for Health Care Workers: Randomized Controlled Trial
Creators: name: Nomeikaite, Auguste
name: Gelezelyte, Odeta
name: Böttche, Maria
name: Andersson, Gerhard
name: Kazlauskas, Evaldas
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: internet interventions
subject: mental health
subject: stress
subject: health care workers
subject: short message service
subject: cognitive behavioral therapy
subject: internet-delivered cognitive behavioral therapy
subject: psychotherapy
classificationCode: 150
subject: Psychologie

description: Background: Prompts offer a promising strategy to promote client engagement in internet-delivered cognitive behavioral therapy (ICBT). However, if the prompts do not meet the needs of clients, they can potentially be more obtrusive rather than helpful. Objective: The aim of this study was to test if prompts tailored based on timing and frequency, aligned with preintervention goal setting, can increase usage and the efficacy of a therapist-supported ICBT stress recovery intervention for health care workers. Methods: The 2-arm randomized controlled trial included 87 health care workers (99% female, aged 19-68 years: mean 39.61, SD 11.49): 43 in the standard intervention group and 44 in the tailored prompts group. The primary outcome measure was the Recovery Experiences Questionnaire, and the secondary outcomes were the Perceived Stress Scale-4, the Patient Health Questionnaire-4, and the World Health Organization-5 Well-Being Index. The self-report data were collected before the intervention (September 2022), postintervention (October 2022), and 6-month follow-up (May 2023). Results: The results showed that tailored prompts, although appreciated by the majority (39/40, 98%), did not improve intervention usage indicators, such as the number of logins (t85=–0.91; P=.36), modules opened (t83.57=–1.47; P=.15), modules completed (t85=–0.71; P=.48), exercises completed (t85=–1.05; P=.30), or the time spent using the program (χ22=1.1; P=.57). Similarly, tailored prompts did not increase the effects of the intervention in terms of stress recovery skills (Cohen d ranging from 0.31 to 0.85), perceived stress (d=–0.08; –0.70), depression (d=–0.11; –0.38), anxiety (d=–0.32; –0.64), or psychological well-being (d=0.26; 0.46). In addition, the standard intervention group showed greater long-term stress recovery effects than the group using the internet-delivered intervention supplemented by tailored prompts (β=–0.24, P=.03). Conclusions: Although the study confirmed the efficacy of the program, the merits of tailored prompts in ICBT for stress recovery were not supported. Future research is needed to test the effects of the stress recovery intervention supplemented by goal setting and tailored prompts. Trial Registration: ClinicalTrials.gov NCT05553210; https://clinicaltrials.gov/study/NCT05553210
Review of Taylor G. Petrey, Tabernacles of Clay: Sexuality and Gender in Modern Mormonism (Durham, NC: University of North Carolina Press, 2020), Choice: Current Reviews for Academic Libraries 58, no. 4
Creators: name: Hurlbut, Dima
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Sexual minorities
subject: History
subject: Mormon Church
subject: Race
subject: Sex

description: This is a book review published in Choice.
Long-range configuration interaction with an ab initio short-range correction and an asymptotic lower bound
Creators: name: Scemama, Anthony
name: Savin, Andreas
Publisher: name: arXiv
Year: 2024
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Short-range corrections to long-range selected configuration interaction calculations are derived from perturbation theory considerations and applied to harmonium (with two to six electrons for some low-lying states). No fitting to reference data is used, and the method is applicable to ground and excited states. The formulas derived are rigorous when the physical interaction is approached. In this regime, the second-order expression provides a lower bound to the long-range full configuration interaction energy. A long-range/short-range separation of the interaction between electrons at a distance of the order of one atomic unit provides total energies within chemical accuracy, and, for the systems studied, provide better results than short-range density functional approximations.
title: Laboratory Acoustic Emissions Reveal Stress Rotation From Preparation Processes Toward Fault Slip on Varying Surface Roughness in Granular Materials
Creators: name: Song, Jiefang
name: Wang, Lei
name: Dresen, Georg
name: Martínez-Garzón, Patricia
name: Vavryčuk, Václav
name: Bohnhoff, Marco
name: Lu, Caiping
name: Kwiatek, Grzegorz
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: acoustic emission
subject: stress rotation
subject: fault slip
subject: fault surface roughness
classificationCode: 550
subject: Geowissenschaften

description: We investigate the influence of fault roughness on physical damage prior to large laboratory rock failure and the evolution of the local stress field surrounding the fault zone as macroscopic shear slip approaches. To achieve this, we analyze acoustic emission (AE) data from displacement-driven rock friction experiments conducted on porous sandstone samples containing either a saw-cut (smooth) or a rough fault. Using high-quality AE-derived focal mechanisms and two stress tensor inversion approaches–one considering double-couple (DC) components and the other one incorporating non-DC components, we examine the temporal evolution of the local stress tensor for both smooth and rough faults. Our results show no significant differences between the two stress inversion methods, indicating that non-DC components have no significant influence on the resulting stress tensors in our experiments. As macroscopic shear slip approaches, the principal stress axes surrounding the fault zone gradually rotate, regardless of the initial fault roughness. The observed evolution of stress tensors correlates with the evolving partitioning between volumetric and shear deformation, as derived from moment tensor inversion of AEs. Compared to the smooth fault, the rough fault exhibits higher local stress heterogeneity and more erratic fluctuations in AE source-related parameters as loading progresses.
title: Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors
Creators: name: Pérez Carrillo, Victor Hugo
name: Whittaker, Jacob J.
name: Wiedemann, Christoph
name: Harder, Jean-Martin
name: Lohr, Theresa
name: Jamithireddy, Anil K.
name: Dajka, Marina
name: Goretzki, Benedikt
name: Joseph, Benesh
name: Guskov, Albert
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: Crystal structure
subject: Immunology
subject: FOS: Clinical medicine
subject: Inhibitors
subject: Ligands
subject: Protein structure
classificationCode: 540
subject: Chemie und zugeordnete Wissenschaften

description: Macrophage infectivity potentiator (MIP) proteins, found in pro- and eukaryotic pathogens, influence microbial virulence, host cell infection, pathogen replication, and dissemination. MIPs share an FKBP (FK506 binding protein)-like prolyl-cis/trans-isomerase domain, making them attractive targets for inhibitor development. We determined high-resolution crystal structures of Burkholderia pseudomallei and Trypanosoma cruzi MIPs in complex with fluorinated pipecolic acid inhibitors. The inhibitor binding profiles in solution were compared across B. pseudomallei, T. cruzi, and Legionella pneumophila MIPs using 1H, 15N, and 19F NMR spectroscopy. Demonstrating the versatility of fluorinated ligands for characterizing inhibitor complexes, 19F NMR spectroscopy identified differences in ligand binding dynamics across MIPs. EPR spectroscopy and SAXS further revealed inhibitor-induced global structural changes in homodimeric L. pneumophila MIP. This study demonstrates the importance of integrating diverse methods to probe protein dynamics and provides a foundation for optimizing MIP-targeted inhibitors in this structurally conserved yet dynamically variable protein family.
The effect and mechanism of sanguinarine against PCV2 based on the analysis of network pharmacology and TMT quantitative Proteomics
Creators: name: Zhang, Sihuan
name: Li, Hongquan
name: Wang, Xuzhen
name: Sun, Panpan
name: Zhang, Hua
name: Yin, Wei
name: Fan, Kuohai
name: Yang, Huizhen
name: Zhang, Zhenbiao
name: Zhong, Jia
name: Sun, Yaogui
name: Sun, Na
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 300911
subject: Veterinary pharmacology
classificationCode: 300906
subject: Veterinary immunology
classificationCode: 300914
subject: Veterinary virology

description: Porcine circovirus type 2 (PCV2) is highly prevalent in nature and serves as the primary pathogen responsible for porcine circovirus-associated disease (PCVD/PCVAD), posing a significant threat to pig production. Currently, vaccination alone could not provide the complete protection for PCV2 infection. The active ingredients of traditional Chinese medicine have shown a positive effect in combating viral infections. This study employed tandem mass tag (TMT) labeled proteomic analyses and network pharmacology to examine the effect and mechanism of sanguinarine against PCV2. IFIH1, IFITM1, p38α, and JNK were identified as the key targets of sanguinarine against PCV2 based on proteomics and network pharmacology. Using PCV2-infected PK-15 cells, it was discovered that sanguinarine inhibited the expression of the PCV2 CAP gene by upregulating IFIH1, thereby promoting STAT1 phosphorylation and activating MAVS expression. This, in turn, facilitated IRF3 phosphorylation, leading to increase IFITM1 expression. Simultaneously, sanguinarine suppressed the expression of the PCV2 CAP gene by inhibiting the expression of p38α, JNK, and p-JNK protein. In conclusion, the results of this study suggest that sanguinarine exerts anti-PCV2 effects through different targets and pathways, which lays the foundation for the subsequent development of new anti-PCV2 veterinary drugs.
TV_MINBES 2025 cruise,Thalassa R/V
Creators: name: Benoit, LOUBRIEU
name: Javier, ESCARTIN
Publisher: name: Sismer
Year: 2025

description: Initiative « Valorisation bathymétrique des transits de la flotte océanographique » L'acquisition de données bathymétriques sur ce transit est à l'initiative d'un groupe de géologues et géophysiciens , en concertation avec la Flotte Océanographique Française. L'objectif global de cette initiative est de généraliser l'acquisition de données de sondeurs multifaisceaux sur les transits des navires de la flotte, en vue de a) compléter les couvertures bathymétriques existantes à moyenne et haute résolution et contribuer à la cartographie bathymétrique globale des océans, b) établir un protocole d'acquisition et traitement des données des transits valorisées, et c) faciliter les travaux de recherche à travers le partage publique des données acquises lors de ces transits. Les données sont destinées à un usage de cartographie moyenne résolution (modèle numérique de terrain au pas de grille d'une centaine de mètres). L'acquisition de données se fait dans un mode contraint : - la vitesse du navire est celle fixée par le transit, sans ajustement vis-à-vis de la qualité des données ou leur résolution. - le sondeur multifaisceaux est placé dans un mode automatique. L'acquisition n'est pas nécessairement suivie en continu par un opérateur spécialisé. - les profils de célérité utilisés pour l'acquisition des données et le calcul des sondes sont établis à partir de tables globales, sans mesure in-situ de température et salinité lors de l'acquisition (de type sondes de température). Les données sont pré-traitées et validées et sont destinées à être mise à disposition à court terme dans la base de données des navires océanographiques Sismer. L'acquisition est limitée aux eaux internationales, pour lesquelles aucune demande d'autorisation n'est nécessaire.
A mean field analysis of the role of indirect transmission in emergent infection events
Creators: name: González, Tomás Ignacio
name: Laguna, María Fabiana
name: Abramson, Guillermo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: We developed a mathematical model to investigate the role of indirect transmission in the spread of infectious diseases, using the illustrative example of sarcoptic mange as a case study. This disease can be transmitted through direct contact between an infected host and a susceptible one, or indirectly when potential hosts encounter infectious mites and larvae deposited in the environment, commonly referred to as fomites. Our focus is on exploring the potential of these infectious reservoirs as triggers for emerging infection events and as stable reservoirs of the disease. To achieve this, our mean field compartmental model incorporates the epidemiological dynamics driven by indirect transmission via fomites. We identify different types of dynamics that the system can go into, controlled by different levels of direct and indirect transmission. Among these, we find a new regime where the disease can emerge and persist over time solely through fomites, without the necessity for direct transmission. This possibility of the system reveals an evolutionary pathway that could enable the parasite to enhance its fitness beyond host co-evolution. We also define a new threshold based on an effective reproductive number, that enables us to predict the conditions for disease persistence. Our model allows us to assess the potential effectiveness of various disease intervention measures by incorporating a feature observed in real systems. We hope this contributes to a better understanding of infectious disease outbreaks.
description: Accepted in Physica A
On Exchange-Correlation Energy in DFT Scenarios
Creators: name: Belhaj, A.
name: Ennadifi, S. E.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Motivated by the considerable importance of material properties in modern condensed matter physics research, and using techniques of the $N_{e}$ -electron systems in terms of the electron density $n_{σe}\left( r\right) $ needed to obtain the ground-state energy $E_{e}$ in Density Functional Theory scenarios, we approach the Exchange-Correlation energy $ E_{xc}\left[ n_{σe}(r)\right] $ by considering the interelectronic position corrections $Δr_{x}^{\uparrow \uparrow ,\uparrow \downarrow }=λ_{x}\left\vert δr^{\uparrow \uparrow }-δr^{\uparrow \downarrow }\right\vert $ and $Δr_{c}^{e_{i}e_{j\neq i}}=λ_{c}\left\vert r-r^{\prime }\right\vert ^{-\left( N_{e}-1\right) ^{-1}}$ corresponding to the spin and the Coulomb correlation effects, respectively, through the electron-electron potential energy. Exploiting such corrections, we get approximate expressions for the exchange $E_{x}\left[ n_{σe} \right] $ and the correlation $E_{c}\left[ n_{σe}\right] $ functional energies which could be interpreted in terms of magnetic and electric dipole potential energies associated with the charge density $n_{σe}\left( r\right) $ described by inverse-square potential behaviors. Based on these arguments, we expect that such obtained Exchange-Correlation functional energy could be considered in the Local Density Approximation functional as an extension to frame such interelectronic effects.
description: 11 Pages, 0 Figures, 0 Tables, Hand-conducted work, Authors in alphabetical order
Ferroelectric AlBN Films by Molecular Beam Epitaxy
Creators: name: Savant, Chandrashekhar
name: Gund, Ved
name: Nomoto, Kazuki
name: Maeda, Takuya
name: Jadhav, Shubham
name: Lee, Joongwon
name: Ramesh, Madhav
name: Kim, Eungkyun
name: Nguyen, Thai-Son
name: Chen, Yu-Hsin
name: Casamento, Joseph
name: Rana, Farhan
name: Lal, Amit
name: Huili
name: Xing
name: Jena, Debdeep
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report the properties of molecular beam epitaxy deposited AlBN thin films on a recently developed epitaxial nitride metal electrode Nb2N. While a control AlN thin film exhibits standard capacitive behavior, distinct ferroelectric switching is observed in the AlBN films with increasing Boron mole fraction. The measured remnant polarization Pr of 15 uC/cm2 and coercive field Ec of 1.45 MV/cm in these films are smaller than those recently reported on films deposited by sputtering, due to incomplete wake-up, limited by current leakage. Because AlBN preserves the ultrawide energy bandgap of AlN compared to other nitride hi-K dielectrics and ferroelectrics, and it can be epitaxially integrated with GaN and AlN semiconductors, its development will enable several opportunities for unique electronic, photonic, and memory devices.
description: DOI: 10.1063/5.0181217
Genomic insights into assembly of α-β hydrolase superfamily genes involved in blast resistance in rice
Creators: name: Zou, Qianmei
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 300110
subject: Transgenesis
classificationCode: 300403
subject: Agronomy

description: Background: The α-βhydrolase gene (ABH) encodes enzymes that catalyze a variety of growth, development, and stress-associatedreactions, playing a crucial role in biological functions. However, despite rice being one of the world's most important cereal crops, the evolution and functional roles of ABHgenes in this species remain poorly understood to date.Results: In present study, bioinformatics analysis was conducted to define and predict OsABH superfamily evolution and function in Oryza indica. OsABH BGIOSGA016507-overexpressed transgenic rice plants were constructed,and assessed itsexpression dynamics of disease resistance factors in response to Magnaporthe oryzaeinfection through RT-qPCR. Meanwhile, endogenous hormones were quantified through ELISA. Forty-one ABHs were identified in O. indica, with synteny analysis revealing OsABH superfamily amplification linked to segmental duplications. The OsABH promoter exhibited multiple biotic and abiotic stress and tolerance-associated cis-acting elements. BGIOSGA016507 haplotypes analysis showed obvious indica bias. Additionally, BGIOSGA016507 responded to blast stress and conjugating salicylic acid signaling pathway to enhance rice resistance to M. oryzae.Conclusions:Forty-one ABH superfamily genes in Oryza indicawere first identified in a comparative genomic scale, and their synteny and evolutionary trajectory were elucidated. Besides, The function of OsABH superfamily—BGIOSGA016507 conjugates the salicylic acid signaling pathway to enhance rice resistance to M. oryzaehas been elucidated through multidimensional ways. These results advance understanding OsABH superfamily evolution and validated ABH involvement in blast resistance in rice.
Stream health and water quality in hill- and high-country deer farms
Creators: name: Thompson, Bryan
name: Muirhead, Richard
name: Ferguson, Colin
name: Bilton, Timothy
name: Ward, Jamie
Publisher: name: AgResearch
Year: 2024
Subjects: classificationCode: 3002
subject: Agriculture, land and farm management

description: Environmental stewardship of the land is a self-valued attribute of many farmers, including those farming in hill- and high-country landscapes (Keeling 2023 et al.). Increased awareness of the environmental implications of meat derived diets from both domestic and international consumers, has resulted in increased critical scrutiny on the environmental footprint of pastoral agriculture. Intensive agricultural practices can result in nutrient rich aquatic environments which are not conducive to diverse natural ecological communities and can negatively impact native flora and fauna species. Additionally, the degradation of these aquatic environments has negatively impacted some public recreational activities further highlighting the negative environmental consequences of some agricultural practices. Hill- and high-country farming systems are generally low intensity, low input operations. Most of the current knowledge and mitigations for agriculture were developed from data collected on low slope intensive agricultural land and have little evidential basis for their effectiveness in hill- and highcountry landscapes. This leaves a paucity of information on the quantified environmental impact of hill- and high-country lower intensity agricultural systems. A research programme was commissioned by DEEResearch in 2017 to collect multi-year data on the impact of deer farming on water quality and stream health in hill- and high-country farming systems to provide scientific evidence to support habitat and farm systems applicable solutions to protect or enhance the environment.
A Qualitative Study on How Usable Security and HCI Researchers Judge the Size and Importance of Odds Ratio and Cohen's d Effect Sizes
Creators: name: Ortloff, Anna-Marie
name: Grohs, Julia Angelika
name: Lenau, Simon
name: Smith, Matthew
Publisher: name: CISPA
Year: 2025

description: Researchers often place a strong focus on statistical significance when reporting the results of statistical tests. However, effect sizes are reported less frequently, and interpretation in the context of the study and the research field is even rarer. These interpretations of effect sizes are, however, necessary to understand the practical importance of a result for the community. To explore how Usable Security & Privacy (USP) and HCI researchers interpret effect sizes and make judgments on practical importance, we conducted survey and interview studies with a total of 63 researchers at CHI and SOUPS 2023. Our studies focused on Cohen’s d and odds ratios in two USP and one HCI scenario. We analyzed which artifacts researchers consider when judging effect size, and found misconceptions and variation between the participants, highlighting how difficult judging statistics can be. Based on our findings, we make concrete recommendations for improved reporting practices around effect sizes.
Publications of BSPU Academic Staff in Scopus and Web of Science 2024
Creators: name: Potapenko, Halyna
name: Kutorha, Alla
Publisher: name: Zenodo
Year: 2025
Subjects: Annual Scientific Index
Bibliographic Index
Research Publications
Scopus
Web of Science
Scientific Productivity
University Research Output
Academic Publications
Science Monitoring
Bibliometric Analysis
Scholarly Publications
Research Performance
Higher Education Research
Ukraine Science Days
BSPU Publications
Berdyansk State Pedagogical University

description: The Annual Scientific and Bibliographic Index of University Researchers’ Publications in the International Databases Scopus and Web of Science is published once a year before the Science Days in Ukraine. The publication systematizes the scientific output of the researchers and academic staff of Berdyansk State Pedagogical University, providing an analytical overview of their works from the previous year. The index is intended for the scientific community, university administration, and librarians as a tool for monitoring scientific productivity.
Additional file 2 of Effect of probiotic supplementation on in-hospital mortality in patients with acute myocardial infarction: a study protocol for an open-label, randomized, controlled, superiority clinical trial
Creators: name: Chen, Yequn
name: Chen, Rongbing
name: Wang, Xin
name: Zhou, Yan
name: Hong, Liekai
name: Xiong, Nianling
name: Zhu, Jinxiu
name: Ye, Shu
name: Tan, Xuerui
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Computational Biology

description: Additional file 2.
Seroepidemiological study of Toxoplasma gondii infection in a population of Iranian epileptic patients
Creators: name: Babaie, Jalal
name: Sayyah, Mohammad
name: Gharagozli, Kourosh
name: Mostafavi, Ehsan
name: Golkar, Majid
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2017
Subjects: epilepsy
Toxoplasma gondii
IgG
ELISA
seroprevalence

description: Epilepsy is one of the most common neurologic disorders. Underlying cause of epilepsy is unknown in 60 % of the patients. Toxoplasma gondii is an intracellular parasite which is capable of forming tissue cysts in brain of chronically infected hosts including humans. Some epidemiological studies suggested an association between toxoplasmosis and acquisition of epilepsy. In this study we determined seroprevalence of latent Toxoplasma infection in a population of Iranian epileptic patients. Participants were classified in three groups as Iranian epileptic patients (IEP, n = 414), non-epileptic patients who had other neurologic disorders (NEP, n = 150), and healthy people without any neurologic disorders (HP, n = 63). The presence of anti-Toxoplasma IgG antibodies and IgG titer in the sera were determined by ELISA method. Anti-T. gondii IgG seroprevalence obtained 35.3 %, 34.7 % and 38.1 % in IEP, NEP and HP, respectively. The seroprevalence rate was not significantly different among the three groups (P = 0.88). Anti-T. gondii IgG titer was 55.7 ± 78, 52.4 ± 74 and 69.7 ± 92 IU/ml in IEP, NEP and HP, respectively. There was not any statistically significant difference in the antibody titer between the study groups (P = 0.32). The rate of T. gondii infection in epileptic patients was not higher than non-epileptic patients and healthy people in the Iranian population.
description: EXCLI Journal; 16:Doc256; ISSN 1611-2156
Перспективи місцевого застосування гентаміцину для лікування бактеріальних інфекцій
Creators: name: Салій, Олена
name: Костюк, Ольга
name: Попова, Марія
Publisher: name: Nordic Sci Publisher
Year: 2023
Subjects: гентаміцину сульфат
аналіз асортименту
лікарська форма
місцеве застосування

description: Гентаміцину  сульфат  належить  до  антибіотиків  групи  аміноглікозидів  II покоління.  Гентаміцин  сульфат  спочатку  має слабку  проникаючу  здатність, пероральна абсорбція практично відсутня, тому Гентаміцин сульфат застосовують парентеральним шляхом, як внутрішньом’язово, внутрішньовенно та локально на шкіру та слизові оболонки. Ряд лікарських фармацевтичних форм можуть являти собою  надійний  спосіб  забезпечити  місцеву  доставку  високої  дози Гентаміцину сульфату, яку можна розподілити по всій хірургічній ділянці або ділянці ураження бактеріальною інфекцією. Асортимент лікарських засобів на основу гентаміцину представлений  та  українському  та  зарубіжному  ринку.  Метою дослідження  було виконати  аналіз  сучасного  асортименту  лікарських  засобів  з  гентаміцину сульфатом  для місцевого застосування  та  визначити  перспективи  використання для  лікування  бактеріальних  інфекцій.  Використано  методи системного  підходу, бібліографічного,  інформаційного  пошуку,  аналізу,  порівняння  та  узагальнення. Оцінено результати клінічних випробувань нових фармацевтичних форм, систем доставки  та  дозувань  для  місцевого  введення Гентаміцину  сульфат.  Об’єктами дослідження  також  слугувала  інформація  щодо  наукових  публікацій  у  мережі інтернет на платформах пошуку наукових цитат та сучасних досліджень вільного та/або  відкритого  доступу. Встановлено,  що  на  українському  фармацевтичному ринку  асортимент  лікарських  засобів  для  місцевого застосування    на  основі гентаміцину  представлений  лише  порошками  та  розчинами  для  зовнішнього застосування, але  на  світовому  фармацевтичному  ринку  додатково  представлені лікарські форми, що забезпечують локальний шлях доставки гентаміцину – мазі та креми, що є підґрунтям для створення вітчизняних лікарських засобів на основі гентаміцину.
The CARMENES search for exoplanets around M dwarfs. Revisiting the GJ 581 multi-planetary system with new Doppler measurements from CARMENES, HARPS, and HIRES
Creators: name: von Stauffenberg, A.
name: Trifonov, T.
name: Quirrenbach, A.
name: Reffert, S.
name: Kaminski, A.
name: Dreizler, S.
name: Ribas, I.
name: Reiners, A.
name: Kürster, M.
name: Twicken, J. D.
name: Rapetti, D.
name: Caballero, J. A.
name: Amado, P. J.
name: Béjar, V. J. S.
name: Cifuentes, C.
name: Góngora, S.
name: Hatzes, A. P.
name: Henning, Th.
name: Montes, D.
name: Morales, J. C.
name: Schweitzer, A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: GJ 581 is a nearby M dwarf known to host a packed multiple planet system with 2 super-Earths and a Neptune-mass planet. We present new orbital analyses of the system, utilizing recent RV data obtained from the CARMENES spectrograph combined with newly reprocessed archival data from the HARPS and HIRES spectrographs. Our aim was to analyze the post-discovery spectroscopic data of GJ 581, which were obtained with CARMENES. In addition, we used publicly available HIRES and HARPS spectroscopic data to seek evidence of the known and disputed exoplanets in this system. We aimed to investigate the stellar activity of GJ 581 and update the planetary system's orbital parameters using state-of-the-art numerical models and techniques. We performed a periodogram analysis of the available precise CARMENES, HIRES, and HARPS RVs and of stellar activity indicators. We conducted detailed orbital analyses by testing various orbital configurations consistent with the RV data. We studied the posterior probability distribution of the parameters fit to the data and explored the long-term stability and overall orbital dynamics of the system. We refined the orbital parameters of the system using the most precise and complete set of Doppler data available. Consistent with the existing literature, we confirm that the system is unequivocally composed of only 3 planets detectable in the present data, dismissing the putative planet GJ 581 d as an artifact of stellar activity. Our N-body fit reveals that the system's inclination is i $=$ 47.0 deg, which implies that the planets could be up to 30% more massive than their previously reported minimum masses. Furthermore, we report that the system exhibits long-term stability, as indicated by the posterior probability distribution, characterized by secular dynamical interactions without the involvement of mean motion resonances.
description: 21 pages, 8 Figures, 5 Tables, 1 Appendix, Accepted for publication in A&A (20th March 2024), Data available at the CDS
Gestão da Capacidade de Carga em Trilhas de Áreas Protegidas
Creators: name: Cintia Cardoso, Capitã
Publisher: name: Zenodo
Year: 2024

description: A gestão eficaz da capacidade de carga é essencial para garantir a sustentabilidade das áreas protegidas. Ao reduzir o número de visitantes e implementar práticas de manejo adequado, podemos preservar a beleza cênica e a biodiversidade dessas áreas para as futuras gerações.
title: Impulsive Behavior Short Scale–8 (I-8)
Creators: name: Groskurth, K.
name: Nießen, D.
name: Rammstedt, B.
name: Lechner, C.
Publisher: name: ZIS - GESIS Leibniz Institute for the Social Sciences
Year: 2022
Subjects: subject: behavior
subject: control
subject: validation

description: The Impulsive Behavior Short Scale–8 (I-8) measures the psychological construct of impulsivity with four subscales comprising two items each (completion time < 1 min). The aim of the present study was threefold: (1) to assess the psychometric properties (objectivity, reliability, and validity) of the English-language I-8; (2) to compare these psychometric properties with those of the original German-language source version of the scale; and (3) to test the cross-national comparability of the scale via measurement invariance tests. For this purpose, we used heterogeneous quota samples from the UK and Germany. Our results indicate that I-8 is a reliable and valid short scale with highly comparable psychometric properties across both language versions. In addition, I-8 showed a highly similar correlational pattern with various extraneous variables across the two nations. Furthermore, partial scalar invariance and full invariance of residual variances held, allowing the comparison of latent means and observed (co)variances across nations. I-8 lends itself as a measure of impulsive behavior especially in surveys in which assessment time is limited, such as in large-scale cross-national surveys.
description: ZIS - The Collection of Items and Scales for the Social Sciences
Supplemental Material, sj-pdf-1-ehp-10.1177_0163278720926714 - Development and Validation of a BMI-Based Figure Rating Scale for Chinese Adolescents
Creators: name: Yu, Chao-Ran
name: Yu, Xin-Yang
name: Fan, Zhi-Tao
name: Wang, Kui
name: Littleton, Heather L.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental Material, sj-pdf-1-ehp-10.1177_0163278720926714 for Development and Validation of a BMI-Based Figure Rating Scale for Chinese Adolescents by Chao-Ran Yu, Xin-Yang Yu, Zhi-Tao Fan, Kui Wang and Heather L. Littleton in Evaluation & the Health Professions
Supplemental_Documents - A Group-Based Walking Study to Enhance Physical Activity Among Older Adults: The Role of Social Engagement
Creators: name: Liu, Yujun
name: Lachman, Margie E.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental_Documents for A Group-Based Walking Study to Enhance Physical Activity Among Older Adults: The Role of Social Engagement by Yujun Liu and Margie E. Lachman in Research on Aging