cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Un meta-modele pour l'automatisation du deploiement d'applications logicielles
Creators: name: Merle, Noelle
Publisher: name: arXiv
Year: 2004
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Le deploiement est maintenant considere comme une activite a part entiere du cycle de vie du logiciel. Les grandes entreprises souhaitent pouvoir automatiser cette etape tout en prenant en compte les caracteristiques de chaque machine cible. Pour repondre a ces besoins, nous avons defini un environnement de deploiement : ORYA (Open enviRonment to deploY Applications). Cet environnement utilise un meta-modele de deploiement, decrit dans ce papier. Notre approche utilise aussi les technologies des federations et des procedes, fournissant un environnement flexible et extensible pour l'utilisateur. ----- The deployment is now a full activity of the software lifecycle. Large enterprises want to automate this step, taking into account characteristics of each target machine. To satisfy these needs, we have defined an environment for the deployment phase: ORYA (Open enviRonment to deploY Applications). This environment uses a deployment metamodel, described in this paper. Our approach is based also on federation and process federations, providing a flexible and extensible environment to the user
Welfare Implications of Washington Wheat Breeding Programs
Creators: name: Nogueira, Lia
name: Marsh, Thomas L.
name: Nogueira, Lia
name: Marsh, Thomas L.
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: welfare
subject: wheat breeding programs
subject: economic surplus
subject: partial equilibrium

description: We calculate the welfare effects of the WSU wheat breeding programs for producers and consumers in Washington State, Oregon, Idaho, the United States and the rest of the world. We develop a partial equilibrium multi-region, multi-product, multi-variety trade model for wheat that provides consumer, producer and total surplus for each wheat class and region. Our results provide evidence suggesting that WSU wheat breeding programs have increased welfare in Washington State, in the United States and the rest of the world.
Producer Preferences and Characteristics in Biomass Supply Chains
Creators: name: Altman, Ira J.
name: Johnson, Thomas G.
name: Moon, Wanki
name: Altman, Ira J.
name: Johnson, Thomas G.
name: Moon, Wanki
Publisher: name: Unknown
Year: 2008
Subjects: Agribusiness

description: Organizational costs in biomass transactions could be a key barrier to commercial development of cellulosic based industries. Understanding biomass producer characteristics and preferences will be important to the future development of renewable industries like cellulosic ethanol. In this paper survey data are analyzed that identify assets biomass producers currently own, services they are willing to provide and their preferences for selling mechanisms. A multinomical logit model is used to analyze producer preferences.
A new look at scalar mesons
Creators: name: Maiani, L.
name: Polosa, A.
name: Piccinini, F.
name: Riquer, V.
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Light scalar mesons are found to fit rather well a diquark-antidiquark description. The resulting nonet obeys mass formulae which respect, to a good extent, the OZI rule. OZI allowed strong decays are reasonably reproduced by a single amplitude describing the switch of a qbar-q pair, which transforms the state into two colourless pseudoscalar mesons. Predicted heavy states with one or more quarks replaced by charm or beauty are briefly described; they should give rise to narrow states with exotic quantum numbers.
description: 4 pages, 1 figure, misprints corrected, references added, accepted for publication in Phys. Rev. Lett
The complex channel networks of bone structure
Creators: name: Costa, Luciano da Fontoura
name: Viana, Matheus Palhares
name: Beletti, Marcelo E.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Biological Physics (physics.bio-ph)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Bone structure in mammals involves a complex network of channels (Havers and Volkmann channels) required to nourish the bone marrow cells. This work describes how three-dimensional reconstructions of such systems can be obtained and represented in terms of complex networks. Three important findings are reported: (i) the fact that the channel branching density resembles a power law implies the existence of distribution hubs; (ii) the conditional node degree density indicates a clear tendency of connection between nodes with degrees 2 and 4; and (iii) the application of the recently introduced concept of hierarchical clustering coefficient allows the identification of typical scales of channel redistribution. A series of important biological insights is drawn and discussed
description: 3 pages, 1 figure, The following article has been submitted to Applied Physics Letters. If it is published, it will be found online at http://apl.aip.org/
Agricultural Trade Liberalisation and Economic Growth in Developing Countries: Analysis of Distributional Consequences
Creators: name: Ali, Ershad
name: Talukder, Dayal
name: Ali, Ershad
name: Talukder, Dayal
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: Community/Rural/Urban Development
subject: Crop Production/Industries
subject: Farm Management
subject: Institutional and Behavioral Economics
subject: International Development
subject: Labor and Human Capital
subject: Land Economics/Use
subject: Political Economy
subject: Research and Development/Tech Change/Emerging Technologies
subject: agriculture
subject: developing countries
subject: growth
subject: inequality
subject: trade liberalisation

description: The article analyses the impact of agricultural trade liberalisation on economic growth as well as on the welfare of rural livelihoods in developing countries through technological transformation in the agricultural sector. The article, based on existing literature, considers the background and reasons for the policy shift in developing economies away from agricultural protection and toward trade liberalisation. It attempts to shed light on the debate over the distributional consequences resulting from trade liberalisation. It also analyses how agricultural trade policy reforms affect poverty and inequality, since the majority of the population of developing countries is involved with agriculture, and these households are predominantly rural poor and functionally landless. The study found that trade liberalisation in the agricultural sector has had positive impacts on the agricultural sector but has contributed very little to poverty reduction because of the lack of income distribution and inequality measures in the policy sphere. The article might be useful for policy makers and researchers.
Natural spaces, utopian places : natural history and the elite project in early independent Mexico
Creators: name: Westgard, Clint
Publisher: name: University of British Columbia
Year: 2009

description: One of the fundamental problems facing the creole elite following independence from Spain was how to construct an identity for themselves as elite citizens and leaders of a republic, rather than elite subjects of a monarch. Mexican intellectuals constituted their authority by establishing specific modes of seeing, derived from the practice of natural history, which allowed them to articulate particular notions about individuals and the nation as naturally ordered. The mode of seeing adopted by the elite required the formation of ideal spaces, spaces outside space, that could act as a position from which they could view the nation as a whole. It is through an investigation of space, specifically conceptualizations of space like the city, the museum and the garden, that allow an exploration of the Mexican elite's notions of the nation, family, the individual and nature. With the authority they claimed from occupying their unique viewing position, the elite justified their reform projects and their attempts to craft a nation and a populace that matched the Utopian imaginings they sought to make apparent in such spaces as the museum, the garden and the city.
SiC Detectors for Sub-GeV Dark Matter
Creators: name: Griffin, Sinéad M.
name: Hochberg, Yonit
name: Inzani, Katherine
name: Kurinsky, Noah
name: Lin, Tongyan
name: Yu, To Chin
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Materials Science (cond-mat.mtrl-sci)
subject: High Energy Physics - Experiment (hep-ex)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We propose the use of silicon carbide (SiC) for direct detection of sub-GeV dark matter. SiC has properties similar to both silicon and diamond, but has two key advantages: (i) it is a polar semiconductor which allows sensitivity to a broader range of dark matter candidates; and (ii) it exists in many stable polymorphs with varying physical properties, and hence has tunable sensitivity to various dark matter models. We show that SiC is an excellent target to search for electron, nuclear and phonon excitations from scattering of dark matter down to 10 keV in mass, as well as for absorption processes of dark matter down to 10 meV in mass. Combined with its widespread use as an alternative to silicon in other detector technologies and its availability compared to diamond, our results demonstrate that SiC holds much promise as a novel dark matter detector.
description: 28 pages, 11 figures
Evaluation on Development Level of Rural Circular Economy in Hebei Province, China
Creators: name: Guo, Ping
name: Sun, Wen-Sheng
name: Guo, Ping
name: Sun, Wen-Sheng
Publisher: name: Unknown
Year: 2009
Subjects: subject: Agribusiness
subject: Rural circular economy
subject: Factor analysis
subject: Cluster analysis
subject: China

description: According to availability of rural data, and the actual situation of economic development in different areas, 1 first grade index, 2 grade indices and 20 third grade indices are selected to establish the measurement index system of circular economic development level in rural areas. According to the relevant data, standardized processing of data is conducted. Evaluation on circular economic level in Hebei Province by Factor Analysis indicates that comprehensive score of Shijiazhuang, Qinghuangdao and Tangshan Cities is the highest, that of Xingtai, Handan, Langfang, Baoding, Cangzhou Cities is at a medium level, and that of Hengshui, Chengde and Zhangjiakou is the lowest. Meanwhile, cluster analysis on data after standardization shows that Handan, Baoding, Qinhuangdao, Xingtai, Langfang, Cangzhou and Hengshui belong to the first class; Shijiazhuang and Tangshan belong to the second class; and Zhangjiakou and Chengde belong to the third class. Thus, we can conclude that rural circular economic status in Hebei Province is determined by the proximity of geography and landscape feature. Finally, countermeasures are put forward to realize the harmonious development of rural economy, society and environment and to promote the process of new socialist countryside construction, such as increasing governments’ input in construction of rural circular economy, promoting the development of rural circular economy from the aspect of industrial policy, promoting the construction of rural circular economic market in adjacent areas, and implementing mandatory public participation.
From the butterfly effect to intrinsic randomness: the spontaneous growth of singular shear flows
Creators: name: Thalabard, Simon
name: Bec, Jérémie
name: Mailybaev, Alexei
Publisher: name: arXiv
Year: 2020
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The butterfly effect is today commonly identified with the sensitive dependence of deterministic chaotic systems upon initial conditions. However, this is only one facet of the notion of unpredictability pioneered by Lorenz, who actually predicted that multiscale fluid flows could spontaneously lose their deterministic nature and become intrinsically random. This effect, which is radically different from chaos, have remained out of reach for detailed physical observations. Here, we substantiate this scenario by showing that it is inherent to the elementary Kelvin--Helmholtz hydrodynamical instability of an initially singular shear layer. We moreover provide evidence that the resulting macroscopic flow displays universal statistical properties that are triggered by, but independent of specific physical properties at micro-scales. This spontaneous stochasticity is interpreted as an Eulerian counterpart to Richardson's relative dispersion of Lagrangian particles, giving substance to the intrinsic nature of randomness in turbulence.
Stable Adversarial Learning under Distributional Shifts
Creators: name: Liu, Jiashuo
name: Shen, Zheyan
name: Cui, Peng
name: Zhou, Linjun
name: Kuang, Kun
name: Li, Bo
name: Lin, Yishi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Machine learning algorithms with empirical risk minimization are vulnerable under distributional shifts due to the greedy adoption of all the correlations found in training data. Recently, there are robust learning methods aiming at this problem by minimizing the worst-case risk over an uncertainty set. However, they equally treat all covariates to form the decision sets regardless of the stability of their correlations with the target, resulting in the overwhelmingly large set and low confidence of the learner.In this paper, we propose Stable Adversarial Learning (SAL) algorithm that leverages heterogeneous data sources to construct a more practical uncertainty set and conduct differentiated robustness optimization, where covariates are differentiated according to the stability of their correlations with the target. We theoretically show that our method is tractable for stochastic gradient-based optimization and provide the performance guarantees for our method. Empirical studies on both simulation and real datasets validate the effectiveness of our method in terms of uniformly good performance across unknown distributional shifts.
description: 11 pages
Assignment of a physical energy scale for the dimensionless interaction energies within the PRIME20 peptide model
Creators: name: Kunze, Thomas
name: Dreßler, Christian
name: Lauer, Christian
name: Sebastiani, Daniel
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 530

description: We present a calibration scheme to determine the conversion factors from a coarse-grained stochastic approximation Monte Carlo approach using the PRIME20 peptide interaction model to atomistic force-field interaction energies at full explicit aqueous solvation. The conversion from coarse-grained to atomistic structures was performed according to our previously established inverse coarse-graining protocol. We provide a physical energy scale for both the backbone hydrogen bonding interactions and the sidechain interactions by correlating the dimensionless energy descriptors of the PRIME20 model with the energies averaged over molecular dynamics simulations. The conversion factor for these interactions turns out to be around 2 kJ/mol for the backbone interactions, and zero for the sidechain interactions. We discuss these surprisingly small values in terms of their molecular interpretation.
The effect of using different EOS in modelling the Alpha Centauri binary system
Creators: name: Miglio, Andrea
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this preliminary study we investigate the effects of using different equations of state (CEFF and OPAL) in the calibration of the binary system Alpha Centauri. Constraints coming from the detection of acoustic oscillations in Alpha Centauri A and B are included in the modelling.
description: 6 pages, 7 figures
Surface Structure Studies of CP Stars in the Age of Space Photometry
Creators: name: Kochukhov, Oleg
Publisher: name: Zenodo
Year: 2024

description: Surface chemical abundance inhomogeneities present is several classes of upper main sequence chemically peculiar (CP) stars give rise to conspicuous rotational photometric variability. This variability provides a unique insight into rotational properties of CP stars and can be correlated with their magnetic fields and surface structure. In this talk, I summarise recent progress in our understanding of the relation between photometric variability and surface characteristics of CP stars. Based on superb photometric data collected by space missions, primarily the TESS satellite, I address the questions of what causes photometric rotational variability, is it a reliable indicator of surface magnetism, and how common is this type of behaviour among different groups of CP stars.
Closed-loop Supply Chain Mode of Ecological Agriculture Embedded with Knowledge Scheme
Creators: name: Qin, Li-Hong
name: Ding, Chao-Xun
name: Wang, Dong
name: Qin, Li-Hong
name: Ding, Chao-Xun
name: Wang, Dong
Publisher: name: Unknown
Year: 2009
Subjects: subject: Agribusiness
subject: Knowledge scheme
subject: Ecological agriculture
subject: Closed-loop supply chain
subject: China

description: According to the theoretical and practical experiences of agricultural supply chain both at home and abroad and the principles of profitability, efficiency, sustainable development, closed-loop supply chain mode of ecological agriculture embedded with knowledge scheme is constructed based on the urban and rural two-way logistics system. This mode is embedded with technical knowledge program of eco-crop cultivation and management during the logistics distribution of agriculture means of production. Profit is obtained through the connection between eco-agricultural production base and market. Support system of this mode is introduced, including technology, policy, management, human resources and financial support. Stage characteristics and evolutionary process of closed-loop supply chain of ecological agriculture are analyzed from the periods of incubation, growth, maturity to recession. Applicability of the closed-loop supply chain mode of ecological agriculture embedded with knowledge scheme is discussed from the aspects of capital, logistics network channels, and human resources coordination. Taking Guangxi Kanghua Ecological Agriculture Plantation Development Co. Ltd, as an example, operation process of supply chain is summarized; and the practical significance and popularization value of closed-loop supply chain of ecological agriculture embedded with knowledge scheme are verified.
Analytical solution for the simulation of ground thermal conditions around planar trench collectors
Creators: name: Ven, Adinda
name: Bayer, Peter
name: Koenigsdorff, Roland
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 550

description: Vertical planar installations in shallow ground are uncommon technological variants for geothermal heat supply. Still, they are of increasing interest when depth and space restrictions do not allow the drilling of boreholes or the installation of horizontal collectors. This work is dedicated to plate-shaped closed-loop heat exchangers that are installed in trenches at a few meters depth. A novel three-dimensional analytical model is presented that accounts for the thermal properties as well as seasonal temperature variation in the ground. The model represents the trench collector as a finite plane source with a specific thermal resistance to simulate the mean temperature of the circulating heat carrier fluid. Both, a detailed dimensional analysis and a successful comparison to numerical simulation are presented. Even though only conductive heat transport is simulated, the model could be validated to the conditions observed at an experimental field site with a trench collector installed at Biberach, Germany. The presented analytical method can serve as an ideal tool for the fast dimensioning of vertical planar heat collectors in practice, and it represents a fundamental framework for the integration of advection or latent heat transfer in frozen ground.
Generation of coherence in an exactly solvable nonlinear nanomechanical system
Creators: name: Singh, A. K.
name: Chotorlishvili, L.
name: Srivastava, S.
name: Tralle, I.
name: Toklikishvili, Z.
name: Berakdar, J.
name: Mishra, S. K.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This study is focused on the quantum dynamics of a nitrogen-vacancy (NV) center coupled to a nonlinear, periodically driven mechanical oscillator. For a continuous periodic driving that depends on the position of the oscillator, the mechanical motion is described by Mathieu elliptic functions. This solution is employed to study the dynamics of the quantum spin system including environmental effects and to evaluate the purity and the von Neumann entropy of the NV-spin. The unitary generation of coherence is addressed. We observe that the production of coherence through a unitary transformation depends on whether the system is prepared initially in mixed state. Production of coherence is efficient when the system initially is prepared in the region of the separatrix (i.e., the region where classical systems exhibit dynamical chaos). From the theory of dynamical chaos, we know that phase trajectories of the system passing through the homoclinic tangle have limited memory, and therefore the information about the initial conditions is lost. We proved that quantum chaos and diminishing of information about the mixed initial state favors the generation of quantum coherence through the unitary evolution. We introduced quantum distance from the homoclinic tangle and proved that for the initial states permitting efficient generation of coherence, this distance is minimal.
description: 22 pages, 12 figures
Boundary Conditions for the Einstein Evolution System
Creators: name: Kidder, Lawrence E.
name: Lindblom, Lee
name: Scheel, Mark A.
name: Buchman, Luisa T.
name: Pfeiffer, Harald P.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: New boundary conditions are constructed and tested numerically for a general first-order form of the Einstein evolution system. These conditions prevent constraint violations from entering the computational domain through timelike boundaries, allow the simulation of isolated systems by preventing physical gravitational waves from entering the computational domain, and are designed to be compatible with the fixed-gauge evolutions used here. These new boundary conditions are shown to be effective in limiting the growth of constraints in 3D non-linear numerical evolutions of dynamical black-hole spacetimes.
description: 21 pages, 12 figures, submitted to PRD
Autonomous task planning and situation awareness in robotic surgery
Creators: name: Ginesi, Michele
name: Meli, Daniele
name: Roberti, Andrea
name: Sansonetto, Nicola
name: Fiorini, Paolo
Publisher: name: arXiv
Year: 2020
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The use of robots in minimally invasive surgery has improved the quality of standard surgical procedures. So far, only the automation of simple surgical actions has been investigated by researchers, while the execution of structured tasks requiring reasoning on the environment and the choice among multiple actions is still managed by human surgeons. In this paper, we propose a framework to implement surgical task automation. The framework consists of a task-level reasoning module based on answer set programming, a low-level motion planning module based on dynamic movement primitives, and a situation awareness module. The logic-based reasoning module generates explainable plans and is able to recover from failure conditions, which are identified and explained by the situation awareness module interfacing to a human supervisor, for enhanced safety. Dynamic Movement Primitives allow to replicate the dexterity of surgeons and to adapt to obstacles and changes in the environment. The framework is validated on different versions of the standard surgical training peg-and-ring task.
description: Submitted to IROS 2020 conference
Additional file 1 of New haplochromine cichlid from the upper Miocene (9–10 MYA) of Central Kenya
Creators: name: Altner, Melanie
name: Ruthensteiner, Bernhard
name: Reichenbacher, Bettina
Publisher: name: figshare
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Geology
subject: FOS: Earth and related environmental sciences

description: Additional file 1. Supplementary Data S1. Comparative material of extant species used for X-ray analysis and assembly of meristic data.
Additional file 1 of The ‘goodness-of-fit’ of fit models: creating a multidimensional survey for person-organisation and person-group fit in health care
Creators: name: J. Herkes
name: L. A. Ellis
name: K. Churruca
name: J. Braithwaite
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1: Supplementary File 1. Includes Table 1. Original fit survey items and their corresponding hypothesised latent. Factors; and Table 2. P-G and P-O fit CFA included items statistical information and factor Loadings.
Prediction of Fermentation Qualities of Baled Corn Stalk Silage with Near Infrared Reflectance Spectroscopy
Creators: name: Li, Yu-Meng
name: Yang, Zhong-Ping
name: Li, Yu-Meng
name: Yang, Zhong-Ping
Publisher: name: Unknown
Year: 2009
Subjects: subject: Agribusiness
subject: Near infrared reflectance spectroscopy
subject: Baled silage
subject: Corn stalk
subject: Fermentation qualities
subject: Calibration model
subject: China

description: Near infrared reflectance spectroscopy (NIRS) was evaluated as a tool to predict the chemical compositions of baled corn stalk silage. A total of 112 samples were used for determination of the pH value, crude protein (CP), crude ash (CA), dry matter (DM) and soluble carbohydrate (WSC). Samples were scanned with near infrared reflectance spectrometer and partial least-squares regression (PLSR) was used to predict the chemical compositions. The coefficients of determination of calibration (R2) and the coefficients of determination of validation (R2v) of the pH value, CP, CA and DM were higher than 0.85. The relative percent differences (RPD) of the pH value, CA and CP were higher than 2.5. The RPD of the WSC was higher than 2.0, and its R2V was 0.72. Therefore, the NIRS can provide accurate prediction of the pH value, CP and CA. It can also provide relatively accurate prediction of DM, but the variation range of DM should be enlarged. Moreover, it can be used for a rough estimate of WSC, but the precision should be improved.
Biochemical and structural characterization of enzymes in the 4-hydroxybenzoate catabolic pathway of lignin-degrading white-rot fungi
Creators: name: Kuatsjah, Eugene
name: Schwartz, Alexa
name: Zahn, Michael
name: Tornesakis, Konstantinos
name: Kellermyer, Zoe A.
name: Ingraham, Morgan A.
name: Woodworth, Sean P.
name: Ramirez, Kelsey J.
name: Cox, Paul A.
name: Pickford, Andrew R.
name: Salvachúa, Davinia
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 580

description: White-rot fungi (WRF) are the most efficient lignin-degrading organisms in nature. However, their capacity to use lignin-related aromatic compounds, such as 4-hydroxybenzoate, as carbon sources has only been described recently. Previously, the hydroxyquinol pathway was proposed for the bioconversion of these compounds in fungi, but gene- and structure-function relationships of the full enzymatic pathway remain uncharacterized in any single fungal species. Here, we characterize seven enzymes from two WRF, Trametes versicolor and Gelatoporia subvermispora, which constitute a four-enzyme cascade from 4-hydroxybenzoate to β-ketoadipate via the hydroxyquinol pathway. Furthermore, we solve the crystal structure of four of these enzymes and identify mechanistic differences with the closest bacterial and fungal structural homologs. Overall, this research expands our understanding of aromatic catabolism by WRF and establishes an alternative strategy for the conversion of lignin-related compounds to the valuable molecule β-ketoadipate, contributing to the development of biological processes for lignin valorization.
A practical approach to testing random number generators in computer algebra systems
Creators: name: Gevorkyan, Migran N.
name: Kulyabov, Dmitry S.
name: Demidova, Anastasia V.
name: Korolkova, Anna V.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mathematical Software (cs.MS)
subject: Symbolic Computation (cs.SC)
subject: FOS: Computer and information sciences

description: This paper has a practical aim. For a long time, implementations of pseudorandom number generators in standard libraries of programming languages had poor quality. The situation started to improve only recently. Up to now, a large number of libraries and weakly supported mathematical packages use outdated algorithms for random number generation. Four modern sets of statistical tests that can be used for verifying random number generators are described. It is proposed to use command line utilities, which makes it possible to avoid low-level programming in such languages as C or C++. Only free open source systems are considered.
description: in English, in Russian
Identifying possible bladder cancer ocupational carcinogens via a case-control study and JEM
Creators: name: Richardson, Kathryn Jane
Publisher: name: University of British Columbia
Year: 2009

description: A significant proportion of cancer development is attributable to exposures to certain chemicals in the workplace. However, examining these occupational exposures is often a difficult and challenging task. In this thesis we use the relatively new approach of applying an extensive JEM (Job Exposure Matrix) to estimate the occupational exposures of 1,062 bladder cancer cases and 8,057 matched other cancer controls. The subjects are all male, and were at least 20 years old and resident in British Columbia when diagnosed with cancer between 1983 and 1990. A self-administered questionnaire provided the occupational histories and confounding information on the study subjects. The cumulative exposure (expected work-years of considerable exposure) to each of 11,132 occupational agents was estimated. The bladder cancer cases were matched to cancer controls of other cancer sites (excluding lung) on age at diagnosis and year of diagnosis. The analysis was performed via conditional logistic regression and the following confounders were taken into account: ethnicity, who completed the questionnaire, smoking duration, and alcohol drinking status. Of the 5,699 agents with at least 3 bladder cancer cases exposed, a significantly increased (5% level) odds-ratio was seen for ever exposure to 646 of them. Of the 3,450 agents with at least 9 bladder cancer cases exposed, 350 exhibited a significantly (5% level) increasing dose-response relationship. After adjusting for multiplicity, a subset of 30 agents was selected that demonstrated sufficient evidence of bladder carcinogeneity. Principal components analysis was performed on the cumulative exposures of these selected agents and 10 independent groups of agents were identified. The groups were mainly distinguished by job. The cumulative exposures to these 30 agents were mainly due to employment in logging, ship and boat building, and construction industries, and in occupations involving motor vehicles (e.g. gasoline service station attendant, mechanic, and truck driver). The selected 30 agents seem to mainly be of petroleum or mineral oil base.
Traintrack Calabi-Yaus from Twistor Geometry
Creators: name: Vergu, Cristian
name: Volk, Matthias
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We describe the geometry of the leading singularity locus of the traintrack integral family directly in momentum twistor space. For the two-loop case, known as the elliptic double box, the leading singularity locus is a genus one curve, which we obtain as an intersection of two quadrics in $\mathbb{P}^{3}$. At three loops, we obtain a K3 surface which arises as a branched surface over two genus-one curves in $\mathbb{P}^{1} \times \mathbb{P}^{1}$. We present an analysis of its properties. We also discuss the geometry at higher loops and the supersymmetrization of the construction.
description: 23 pages, 5 figures
Additional file 1 of Involvement of the pulmonary arteries in patients with Takayasu arteritis: a prospective study from a single centre in China
Creators: name: Xiufang Kong
name: Ma, Lili
name: Lv, Peng
name: Xiaomeng Cui
name: Rongyi Chen
name: Zongfei Ji
name: Huiyong Chen
name: Lin, Jiang
name: Lindi Jiang
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: Computational Biology

description: Additional file 1: Figure S1. The flow chart of this study. Table S1. mPAP detected by RHC. Figure S2. Improvement of perfusion defects upon lung VQ scan in a patient with TA. Figure S3. Low perfusion upon MRA in patients with TA.
The Computational Power of the W and GHZ states
Creators: name: D'Hondt, Ellie
name: Panangaden, Prakash
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is well understood that the use of quantum entanglement significantly enhances the computational power of systems. Much of the attention has focused on Bell states and their multipartite generalizations. However, in the multipartite case it is known that there are several inequivalent classes of states, such as those represented by the W-state and the GHZ-state. Our main contribution is a demonstration of the special computational power of these states in the context of paradigmatic problems from classical distributed computing. Concretely, we show that the W-state is the only pure state that can be used to exactly solve the problem of leader election in anonymous quantum networks. Similarly we show that the GHZ-state is the only one that can be used to solve the problem of distributed consensus when no classical post-processing is considered. These results generalize to a family of W- and GHZ-like states. At the heart of the proofs of these impossibility results lie symmetry arguments.
description: 11 pages, substantial rewrite based on referee reports
Primary headache attributed to external compression or traction to the head : a narrative review
Creators: name: Hensel, Ole
name: Kraya, Torsten
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2025
Subjects: subject: 610

description: Background: The aim of this review is to synthesize the existing knowledge regarding headaches attributed to external physical stimuli, as classified by the ICHD-3 (Group 4.6). Two forms can be distinguished in this group: (1) headache attributed to external compression and (2) headache attributed to external traction. Methods: A comprehensive literature review was conducted using the Medline (PubMed) database and other relevant academic sources. All English-language articles were subjected to a relevance assessment. Results: The prevalence of the two types of headache varies considerably, with a higher incidence observed in women or in the presence of predisposing factors (e.g., work with compulsory helmets or long hair). An external-compression headache is typically described as a pressing sensation, whereas an external-traction headache is characterized by a sensation of pulling. The headaches typically persist for less than an hour after the stimulus has ceased, and the intensity is typically reported as mild to moderate. Apart from avoiding the trigger, which is not always possible, effective therapies have not been established. Conclusion: Both types of headaches are relatively common, yet they remain underrepresented in the scientific literature. Furthermore, there is a dearth of comprehensive overviews. If the triggering factor cannot be eliminated, both types of headaches can interfere with daily living and working.
The Femto-experiment for the LHC: The W-boson beams and their targets
Creators: name: Krasny, M. W.
name: Jadach, S.
name: Placzek, W.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The LHC has been designed as a collider of proton and ion beams. However, in its experimental program, which is focused mainly on studies of high energy transfer collisions of Standard Model point-like particles, protons and ions will play a backstage role. For the majority of the LHC experimentalists, their role will be confined to providing standardized, acceleration-process-stable envelopes for tunable-density and tunable-isospin bunches of Standard Model constituents: quarks and gluons. The inter-bunch environment of collisions of these Standard Model particles specific to hadronic colliders and absent in the leptonic ones, has always been considered as a burden - an annoying but unavoidable price to pay for increasing the collision-energy of point-like particles in the storage rings. In this paper we shall argue that such a burden can be converted into an important merit of the high-energy hadronic colliders - a corner-stone for a fermi-length-scale ``collision-experiment'' employing the bunches of spectator quarks and gluons as tunable ``femtoscopic'' targets for the beams of short-living electroweak bosons.
description: 38 pages, 15 eps figures
Additional file 1 of PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures
Creators: name: Emon, Mohammad Asif
name: Domingo-Fernández, Daniel
name: Hoyt, Charles Tapley
name: Hofmann-Apitius, Martin
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. This text file contains all supplementary text, tables and figures referenced in the manuscript.
Systematic review and meta-analysis of the prognostic role of fibroblast-activation protein in gastrointestinal cancers
Creators: name: Sunami, Yoshiaki
name: Bai, Rubing
name: Friedrichs, Juliane
name: Ronellenfitsch, Ulrich
name: Gomes Dos Santos Ferreira Rebelo, Artur Luis
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Gastrointestinal (GI) cancers, particularly pancreatic cancer, are characterized by a dense stromal tumor microenvironment where cancer-associated fibroblasts (CAFs) predominate. CAFs comprise highly heterogeneous subpopulations with different functions, which can be both tumor-promoting and tumor-restraining. This systematic review and meta-analysis aims to comprehensively assess the impact of the CAF marker fibroblast-activation protein (FAP) expression on clinical outcomes in GI cancers. Methods: Adhering to PRISMA guidelines, we systematically searched PubMed/MEDLINE, Web of Science, Cochrane Library, and ClinicalTrials.gov for relevant articles. Inclusion criteria involved studies comparing GI cancer patients with and without FAP overexpression. Meta-analysis evaluated overall survival (OS), histological differentiation, local tumor invasion, lymph node metastases, and distant metastases. For each observational study, the risk of bias was assessed using the risk of bias in non-randomized studies of exposure (ROBINS-E) tool. Results: The meta-analysis included 31 cohort studies from six countries, comprising 3,976 patients. Patients without FAP overexpression exhibited a favorable OS [hazard ratio (HR) =1.74; 95% confidence interval (CI): 1.51–2.01]. Subgroup analyses revealed consistent results across esophageal, pancreatic, colorectal, and gastric cancers. While one-year survival rates showed no significant difference, subsequent years displayed lower rates for FAP-overexpressing groups. Lymph node metastases were more frequent in FAP-overexpressing patients, whereas distant metastases did not differ. None of 31 studies systematically controlled confounding and adjusted data so that all studies were categorized as “high risk of bias” for the domain “risk of bias due to confounding”. For domains “risk of bias arising from measurement of exposure”, “risk of bias due to post-exposure interventions”, “risk of bias arising from measurement of outcomes”, and “risk of bias in selection of the reported result”, all studies were categorized as “low risk of bias”. Conclusions: This meta-analysis underscores the potential adverse prognostic significance of FAP expression in GI cancers. Limitations include heterogeneity in FAP expression cutoffs and definitions. Future research should focus on delineating the precise roles and clinical implications of FAP in GI cancers.
An Attractive Scenario for Light Dark Matter Direct Detection
Creators: name: Davoudiasl, Hooman
name: Denton, Peter B.
name: Gehrlein, Julia
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Direct detection of light dark matter (DM), below the GeV scale, through electron recoil can be efficient if DM has a velocity well above the virial value of $v\sim 10^{-3}$. We point out that if there is a long range attractive force sourced by bulk ordinary matter, i.e. baryons or electrons, DM can be accelerated towards the Earth and reach velocities $v\sim 0.1$ near the Earth's surface. In this "attractive scenario," all DM will be boosted to high velocities by the time it reaches direct detection apparatuses in laboratories. Furthermore, the attractive force leads to an enhanced DM number density at the Earth facilitating DM detection even more. We elucidate the implications of this scenario for electron recoil direct detection experiments and find parameters that could lead to potential signals, while being consistent with stellar cooling and other bounds. Our scenario can potentially explain the recent excess in electron recoil signals reported by the XENON1T experiment in the $\sim$ keV energy regime as well as the hint for non-standard stellar cooling.
description: 6 pages, 4 figures, comments welcome; v2: 7 pages, 4 figures, model signal improved and additional hints considered, matches published version; v3: corrected typos in eqs. 3-4, results unchanged
Design of Agricultural Cleaner Production Technology System
Creators: name: Hu, Jun-Mei
name: Wang, Xin-Jie
name: Hu, Jun-Mei
name: Wang, Xin-Jie
Publisher: name: Unknown
Year: 2009
Subjects: subject: Agribusiness
subject: Non-point source pollution
subject: Agricultural cleaner production
subject: Technology system
subject: China

description: Based on the introduction of agricultural cleaner production, technology system design of planting cleaner production is discussed from five aspects of water-saving irrigation technology, fertilization technology, diseases and insects control technology, straw comprehensive utilization technology and plastic film pollution control technology. Cleaner production technology system of livestock and poultry raise is constructed from the aspects of source control technology, reduction technique in breeding process and end control technology. Thus, the implementation of agricultural cleaner production technology system has profound impact on the agricultural sustainable development in China.
Direct GPCR-EGFR interaction enables synergistic membrane-to-nucleus information transfer
Creators: name: Gekle, Michael
name: Eckenstaler, Robert
name: Braun, Heike
name: Olgac, Abdurrahman
name: Robaa, Dina
name: Mildenberger, Sigrid
name: Dubourg, Virginie
name: Schreier, Barbara
name: Sippl, Wolfgang
name: Benndorf, Ralf
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: We addressed the heteromerization of the epidermal growth factor receptor (EGFR) with G-protein coupled receptors (GPCR) on the basis of angiotensin-II-receptor-subtype-1(AT1R)-EGFR interaction as proof-of-concept and show its functional relevance during synergistic nuclear information transfer, beyond ligand-dependent EGFR transactivation. Following in silico modelling, we generated EGFR-interaction deficient AT1R-mutants and compared them to AT1R-wildtype. Receptor interaction was assessed by co-immunoprecipitation (CoIP), Förster resonance energy transfer (FRET) and fluorescence-lifetime imaging microscopy (FLIM). Changes in cell morphology, ERK1/2-phosphorylation (ppERK1/2), serum response factor (SRF)-activation and cFOS protein expression were determined by digital high content microscopy at the single cell level. FRET, FLIM and CoIP confirmed the physical interaction of AT1R-wildtype with EGFR that was strongly reduced for the AT1R-mutants. Responsiveness of cells transfected with AT1R-WT or –mutants to angiotensin II or EGF was similar regarding changes in cell circularity, ppERK1/2 (direct and by ligand-dependent EGFR-transactivation), cFOS-expression and SRF-activity. By contrast, the EGFR-AT1R-synergism regarding these parameters was completely absent for in the interaction-deficient AT1R mutants. The results show that AT1R-EGFR heteromerisation enables AT1R-EGFR-synergism on downstream gene expression regulation, modulating the intensity and the temporal pattern of nuclear AT1R/EGFR-information transfer. Furthermore, remote EGFR transactivation, via ligand release or cytosolic tyrosine kinases, is not sufficient for the complete synergistic control of gene expression.