cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Deja tu huella en la Investigación: taller
Creators: name: González-Rey, Elena
name: Pérez Sánchez-Cañete, María
name: Canet, Luz
name: Pérez Falo, Clara
Publisher: name: CSIC - Instituto de Parasitología y Biomedicina López Neyra (IPBLN)
Year: 2023
Subjects: subject: Taller
subject: Divulgación
subject: Investigación biomédica

description: Apto para público con discapacidad: Personas con discapacidad física motora/orgánica; Personas con discapacidad visual; Personas con discapacidad auditiva; Personas con discapacidad cognitiva/intelectual; Personas con TEA (Trastorno del Espectro Autista); Personas aisladas (geográficamente, hospitalizadas, encarceladas...); Personas socioeconómicamente vulnerables o en riesgo de exclusión social; Otros públicos
description: Edad recomendada: Apto para todas las edades
description: Tipos de público: Todos los públicos; Apto para públicos con discapacidad
description: El recurso ha formado parte del evento: La Noche de la Investigación
description: El objetivo de este taller es que los participantes aprendan los diferentes aspectos en los que la investigación biomédica se encuentra centrada actualmente y ver si coincide con las necesidades de la sociedad actual. En este taller estamos interesados en mostrar diferentes temas de interés biomédico en los que se trabaja en la actualidad. Enfermedades como la infección por el Coronavirus, el cáncer, la artritis reumatoide, la esclerosis múltiple, infecciones parasitarias, etc., se representarán en una cartulina para que todo el que quiera elija mediante una pegatina su preferencia a la hora de destinar fondos, personal y conocimientos para su investigación y desarrollo de tratamientos. Las pegatinas tendrán diferentes colores relacionados con 3 rangos de edad: 5-10 años (rojo); 11-17 años (azul); mayores de 17 años (verde), para poder evaluar posteriormente la visión y perspectiva mayoritaria de la Ciencia actual y sus necesidades en los diferentes grupos. Esta actividad es apta para todos los públicos, desde menores en edad escolar (infantil, primaria o ESO) hasta personas mayores de 65 años.
Additional file 1 of CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD
Creators: name: Govoni, Mirco
name: Bassi, Michele
name: Girardello, Luca
name: Lucci, Germano
name: Rony, François
name: Charretier, Rémi
name: Galkin, Dmitry
name: Faietti, Maria Laura
name: Pioselli, Barbara
name: Modafferi, Gloria
name: Benfeitas, Rui
name: Bonatti, Martina
name: Miglietta, Daniela
name: Clark, Jonathan
name: Pedersen, Frauke
name: Kirsten, Anne-Marie
name: Beeh, Kai-Michael
name: Kornmann, Oliver
name: Korn, Stephanie
name: Ludwig-Sengpiel, Andrea
name: Watz, Henrik
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
The Impact of Food Prices on Conflict Revisited
Creators: name: Jasmien De Winne
name: Peersman, Gert
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Plant Biology

description: Studies that examine the impact of food prices on conflict usually assume that (all) changes in international food prices are exogenous shocks for individual countries or local areas. By isolating strictly exogenous shifts in global food commodity prices, we show that this assumption could seriously distort estimations of the impact on conflict in African regions. Specifically, we show that increases in food prices that are caused by harvest shocks outside Africa raise conflict significantly, whereas a “naive” regression of conflict on international food prices uncovers an inverse relationship. We also find that higher food prices lead to more conflict in regions with more agricultural production. Again, we document that failing to account for exogenous price changes exhibits a considerable bias in the impact. In addition, we show that the conventional approach to evaluate such effects; that is, estimations that include time fixed effects, ignores an important positive baseline effect that is common for all regions.
International Rice Outlook, Baseline Projections 2014-2024
Creators: name: Wailes, Eric J.
name: Chavez, Eddie C.
name: Wailes, Eric J.
name: Chavez, Eddie C.
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agricultural and Food Policy
subject: Crop Production/Industries
subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: International Relations/Trade
subject: Rice
subject: International
subject: Outlook
subject: Baseline
subject: Projections

description: This outlook contains updated baseline rice projections from the Arkansas Global Rice Economics Program (AGREP) for the U.S. and international rice economies. The purpose of this document is to present the current state and the expected directions of the rice economies in the world by assessing their potential supply and demand paths over the next decade. This set of projections serves as a baseline for evaluating and comparing alternative macroeconomic, policy, weather, and technological scenarios. The estimates are intended for use by government agencies and officials, farmers, consumers, agribusinesses and other stakeholders who conduct medium- and long-term planning. The AGREP baseline projections are grounded in a series of assumptions about the general economy, agricultural policies, weather, and technological change. It is generally assumed that current agricultural policies will continue in the United States and other countries reported in this study. The projections included in this outlook are based on information available as of January 2015. In light of the volatility of the global rice economy, a stochastic analysis is included in this report to provide a better understanding of the probable distribution of future outcomes. The stochastic estimates establish likely upper and lower bounds for selected variables.
Emergence of Geometric phase shift in Planar Non-commutative Quantum Mechanics
Creators: name: Biswas, Saptarshi
name: Nandi, Partha
name: Chakraborty, Biswajit
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Appearance of adiabatic geometric phase shift in the context of noncommutative quantum mechanics is studied using an exactly solvable model of 2D simple harmonic oscilator in Moyal plane, where momentum non-commutativity are also considered along with spatial noncommutativity. After finding a suitable Bopp shift, that bridges the noncommutative phase space operators with their effective commutative counterparts, having their dependence on the non-commutative parameters, we study the adiabatic evolution in the Heisenberg picture. An explicit expression for the geometric phase shift under adiabatic approximation is then found without using any perturbative technique. Lastly, this phase is found to be related to the Hannay angle of a classically analogous system, by studying the evolution of the coherent state of this system.
title: Pulseras de ADN: taller
Creators: name: González-Rey, Elena
name: Pérez Sánchez-Cañete, María
name: Canet, Luz
name: Pérez Falo, Clara
Publisher: name: CSIC - Instituto de Parasitología y Biomedicina López Neyra (IPBLN)
Year: 2023
Subjects: subject: Taller
subject: Divulgación
subject: Adn

description: Apto para público con discapacidad: Personas con discapacidad física motora/orgánica; Personas con discapacidad auditiva; Personas con discapacidad cognitiva/intelectual; Personas con TEA (Trastorno del Espectro Autista); Personas aisladas (geográficamente, hospitalizadas, encarceladas...); Personas socioeconómicamente vulnerables o en riesgo de exclusión social
description: Edad recomendada: 0-6 años; 6-12 años; 12-16 años; 16-18 años; Público adulto; Apto para todas las edades
description: Tipos de público: Todos los públicos; Apto para públicos con discapacidad; Estudiantes de Infantil; Estudiantes ESO; Estudiantes Primaria; Personas mayores; Público familiar; Público general; Público infantil
description: El recurso ha formado parte del evento: La Noche de la Investigación; Semana de la Ciencia y la Tecnología; Día de la Mujer y la Niña en la Ciencia (11F); Feria de la Ciencia
description: En este taller, los participantes aprenden qué es el material genético que forma parte de todas las células utilizando gomas de plástico de cuatro colores. Cada color representará un nucleótido del ADN (la base de la vida). Mediante la combinación de dichas gomas y colores, y la formación de pulseras, los participantes podrán crear diferentes «genes». Podrán llevarse este gen ficticio a casa directamente en su muñeca. Esta actividad es apta para todos los públicos, desde menores en edad escolar (primaria o ESO) hasta personas mayores de 65 años.
THE SPREAD OF RETAIL FOREIGN CURRENCY LOANS IN HUNGARY
Creators: name: Nagy, Éva Lotti
name: Csernák, József
name: Nagy, Éva Lotti
name: Csernák, József
Publisher: name: Unknown
Year: 2015
Subjects: subject: Consumer/Household Economics
subject: Financial Economics
subject: foreign currency loans
subject: retail
subject: exchange rate
subject: CHF
subject: devizahitelek
subject: lakosság
subject: árfolyam

description: We chose the problem of the currency loan for our topic because the over-indebtedness of the Hungarian population is a timely and controversial topic. In our opinion, it is important not only for the banks and the government how creditability is changing in Hungary but also an essential question for the dwellers because there are so many people without using modern financial tools in our country. In our paper we examine the changing of the currency loans and bank loans in forint through a case-study and we make a conclusion which loan was the more favourable one. Furthermore, we examine a process to trace down the reasons of evolving, proceeding and managing the crisis. After the accession to the EU, the currency based credit exposure became widespread in the Hungarian bank system and from this aspect we would like to begin and analyse the process. The problems related to loans are continually growing during the years. The questions occur when and how this unbearable situation should have been solved. In our work we analyse the relationship between the past years and the growing exchange rates. We examine different rescue packages and whether they make people’s lives easier. We have heard a lot about the exchange rate gap. In our study we present the different terms to use this kind of aid. -------------------------------------------------------------- A magyar lakosság eladósodottsága sokak számára egy aktuális és vitatott téma. Nem csak a bankok és a kormány számára fontos, hogy miként alakul a hitelezés Magyarországon, hanem az emberek számára is egy mindennapos kérdés, ugyanis egyre kevesebben vannak ma Magyarországon, akik nem hasznának fel a hétköznapi élethez modern pénzügyi eszközöket. Cikkünkben egy esettanulmányon keresztül vizsgáljuk, a devizahitelek és a forinthitelek változását és így következtetünk arra, hogy melyik hitel volt a kedvezőbb. Továbbá egy folyamatot vizsgálunk, hogy felvázoljuk a válság kialakulásának főbb okait, folyamatát és kezelését. Hazánk Európai Unióhoz csatlakozását követően a magyar bankszektorban elterjedt a deviza alapú hitelezés, ebből az aspektusból szeretnék kiindulni és a folyamatot elemezni. A problémák a hitelekkel kapcsolatosan folyamatosan sorakoztak fel az eltelt évek alatt. Továbbá, elemezzük, hogy mit csinálnak most a bankok így, hogy a lakosság bizalmatlanná vált velük szemben. Napjainkban előtérbe került a problémakör, a hozzá kapcsolódó kormányzati intézkedések, amik majdnem minden bankot érzékenyen fognak érinteni. Összességében elmondható, hogy nem lehet a problémát teljes mértékben a bankokra hárítani. Kérdéses az is, hogy például a média vagy a pénzügyi ismeretek megléte milyen hatást gyakorol a lakosság eladósodottságára.
Evolutionary synthesis models of starbursts IV. Soft X-ray emission
Creators: name: Cervino, M.
name: Mas-Hesse, J. M.
name: Kunth, D.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this work we investigate the evolution of the X-ray emission of a cluster of single young massive stars with different metallicities. We have considered the X-ray contribution originated by the diffuse gas heated by the mechanical energy released by stellar winds and SN explosions as well as the X-ray contribution from SN remnants. The resulting ionizing spectrum (i.e. lambda < 912 A) has been used to compute the expected intensity of the nebular He II 4686 A. The observational ratio He II/Hbeta could be reproduced by the models assuming that a fraction of the mechanical energy produced by the star-formation episode is reprocessed by interaction with the ISM as soft X-ray radiation, contributing to the He ionization. However, the discreteness of the stellar populations affects the ionizing flux and may be responsible for the observed dispersion of the ratio. We have finally used the synthesis models to estimate the contribution of circumnuclear star-forming regions to the multiwavelength energy distribution in Active Galactic Nuclei, finding that the UV to soft X-ray continuum in many Seyfert 2 galaxies seems to be dominated by star-formation processes.
description: 14 pages, 10 fig, A&A accepted
Lathrobium reticolle ASSING 2013
Creators: name: Assing, Volker
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Lathrobium
Lathrobium reticolle

description: Lathrobium reticolle ASSING, 2013 Material examined: China: Yunnan: 3 exs., Haba Shan, 27°22'N, 100°07'E, 3830 m, sifted, 19.VI.2012, leg. Grebennikov (CAS, cAss); 1 ex., Haba Shan, 27°21'N, 100°07'E, 3450 m, sifted, 24.VI.2012, leg. Grebennikov (cSme). Comment: The above material was collected close to the type locality (ASSING 2013 c).
description: Published as part of Assing, Volker, 2015, New species and additional records of Lathrobium and Elytrobium from the Palaearctic region, with special reference to the fauna of East Yunnan (Coleoptera: Staphylinidae: Paederinae), pp. 41-74 in Beiträge Zur Entomologie = Contributions to Entomology 65 (1) on page 49, DOI: 10.21248/contrib.entomol.65.1.41-74, http://zenodo.org/record/4753882
description: {"references": ["ASSING, V. 2013 c: On the Lathrobium fauna of China V. New species and additional records from Yunnan (Coleoptera: Staphylinidae: Paederinae). - Contributions to Entomology 63 (1): 53 - 128."]}
Hesione Robineau-Desvoidy 1863
Creators: name: Evenhuis, Neal L.
name: O'Hara, James E.
name: Pape, Thomas
name: Pont, Adrian C.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Annelida
Polychaeta
Phyllodocida
Hesionidae
Hesione

description: 243. Hesione Robineau-Desvoidy, 1863a: 199.
 ORIGINALLY INCLUDED SPECIES: Hesione microcera Robineau-Desvoidy, 1863.
 TYPE SPECIES: Hesione microcera Robineau-Desvoidy, 1863, by original designation.
 CURRENT STATUS: Preoccupied by Rafinesque, 1815; Lamarck, 1818; Savigny, 1818; junior synonym of Macquartia Robineau-Desvoidy, 1830 [teste Herting & Dely-Draskovits (1993: 312)].
FAMILY: TACHINIDAE.
description: Published as part of Evenhuis, Neal L., O'Hara, James E., Pape, Thomas & Pont, Adrian C., 2010, 2373, pp. 1-265 in Zootaxa 2373 on page 89
Study of the eta-proton interaction via the reaction p p --> p p eta
Creators: name: Moskal, P.
name: Adam, H. H.
name: Budzanowski, A.
name: Czyzykiewicz, R.
name: Gotz, T.
name: Grzonka, D.
name: Jarczyk, L.
name: Khoukaz, A.
name: Kilian, K.
name: Kolf, C.
name: Kowina, P.
name: Lang, N.
name: Lister, T.
name: Oelert, W.
name: Quentmeier, C.
name: Santo, R.
name: Schepers, G.
name: Sefzick, T.
name: Siemaszko, M.
name: Smyrski, J.
name: Steltenkamp, S.
name: Strzalkowski, A.
name: Winter, P.
name: Wolke, M.
name: Wustner, P.
name: Zipper, W.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A measurement of the pp --> p p eta reaction at the excess energy of Q = 15.5 +- 0.4 MeV has been carried out at the internal beam facility COSY-11 with an integrated luminosity of 811 nb^-1 The number of ~24000 identified events permits a precise determination of total (2.32 +- 0.05 +- 0.35 μb) and differential cross sections. Preliminary investigations show that the angular distribution of the eta meson in the center-of-mass system is isotropic. A qualitative analysis of the Dalitz-plot distribution is presented.
description: 3pp, Talk given at 9th International Symposium on Meson - Nucleon Physics and the Structure of the Nucleon (MENU 2001), Washington, District of Columbia, 26-31 Jul 2001. To be published in pN Newsletter 16 (2001)
Relative Risk Perception and the Puzzle of Covered Call Writing
Creators: name: Siddiqi, Hammad
name: Siddiqi, Hammad
Publisher: name: Unknown
Year: 2015
Subjects: subject: Financial Economics
subject: Risk Perception
subject: Relative Risk Perception
subject: Covered Call Writing
subject: Informational Efficiency
subject: Anchoring
subject: Behavioral Finance

description: Market professionals with decades of experience typically argue that a call option is a surrogate for the underlying asset, indicating that they perceive the risk of a call option as similar to the risk of the underlying asset. Experimental evidence also points to the same conclusion. Such relative risk perception is in sharp contrast with finance theory, which argues that only the absolute quantity of risk contained in a call option should matter for its price. I show that relative risk perception provides a potential explanation for the puzzling performance of covered call writing.
Note Illustrative della Carta geologica d'Italia alla scala 1:50.000, F. 339 Teramo
Creators: name: Brozzetti, F.
name: Boncio, P.
name: Lavecchia, G.
Publisher: name: INFN Open Access Repository
Year: 2010

description: Note illustrative redatte per il Foglio geologico n. 339 Teramo della Carta Geologica d'Italia alla scala 1:50.000. 78 pp.
Posing Constraints on the Free Parameters of a New Model of Dark Energy EoS : Responses Through Cosmological Behaviours
Creators: name: Biswas, Promila
name: Roy, Parthajit
name: Biswas, Ritabrata
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Since the late 1990's observations of type Ia Supernova, our universe is predicted to experience a late time cosmic acceleration. Theoretical support to this observation were intended to be built via proposition of a hypothetical fluid which staying inside the universe exerts negative pressure. Cosmologists have prescribed many candidates for this exotic fluid so far. In this alley, a popular method is to choose time dependent equation of state parameter $ω= \frac{p}ρ$ and to parametrize it as a function of redshift. Again some common families of such parametrizations are constructed among which different members justify different properties of observed universe. Mainly, these were model dependent studies which comprise free parameters to be constrained by different observations. In this present article, a new expression for redshift parametrization is considered and we have constrain its free parameters for two Hubble parameter vs redshift data sets. These data sets are obtained depending on two basic methodologies known as different ages method and baryonic acoustic oscillation method. Different confidence contours for our model are located under the constraints of said data sets. Besides, different thermodynamic parameters related to the evolution of our universe are analysed. It is notified that our model indicates towards a delayed dark matter model which mimics EoS = $-1(Λ)$ phenomena at the present epoch. Deceleration parameters behaviour's are studied. It is noticed that a possibility of future deceleration may occur for this new model. Outcomes for both the data sets are compared with each other.
description: 18 pages, 20 figures, 6 tables
Sectoral and spatio-temporal differentiation in technical efficiency: A meta-regression
Creators: name: Djokoto, Justice G.
name: Gidiglo, Ferguson K.
name: Srofenyoh, Francis Y.
name: Agyei-Henaku, Kofi Aaron A-O.
name: Akua A. Afrane Arthur
name: Badu-Prah, Charlotte
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Science Policy
subject: Plant Biology

description: In the literature, existing meta-regressions on efficiency have focused on specific sectors in a country or multiple country and on specific economic activity. None of the available efficiency meta-regressions covers multiple sectors of an economy. We contribute to the literature by investigating the technical efficiency differentiation within a multi-sectoral environment. Using data from 152 publications yielding 223 observations from diverse sources and applying meta-regression analysis, we investigated the heterogeneity in mean technical efficiency (MTE), assessed the temporal and spatial drivers of estimated technical efficiency for Ghana. We found heterogeneity in the estimated MTE. The selected cauchit functional form of the fractional regression model showed sectoral and spatial variables drive heterogeneity in MTE. There was a seeming technical efficiency regression with average MTE of 0.676 that requires greater effort in the management of production than has been the case previously in order to close the output gap.
Additional file 1 of Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus
Creators: name: Wang, Frank Qingyun
name: Dang, Xiao
name: Su, Huidong
name: Lei, Yao
name: She, Chun Hing
name: Zhang, Caicai
name: Chen, Xinxin
name: Yang, Xingtian
name: Yang, Jing
name: Feng, Hong
name: Yang, Wanling
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary Material 1: Supplementary Fig. 1. PCA plots of all the samples from the five datasets. (A) PCA plot prior to batch correction. (B-E) Batch effect across different datasets are minimized after limma::removeBatchEffect according the PCA plots. We identified and removed an outlier (marked in the red circle).
Synthesis and molecular docking of some new bis-thiadiazoles as anti-hypertensive α-blocking agents
Creators: name: El-Enany, Waleed A. M. A.
name: Gomha, Sobhi M.
name: El-Ziaty, Ahmed K
name: Hussein, Wesam
name: Abdulla, Mohamed M.
name: Hassan, Shaimaa A.
name: Sallam, Hanan A.
name: Ali, Rania S.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences

description: Twelve bis-thiadiazole derivatives were synthesized in high yield via the reaction of 2,2′-terephthaloyl bis(N-phenylhydrazine carbothioamide) with a variety of hydrazonoyl chlorides in ethanol containing catalytic amounts of TEA. All the newly synthesized compounds were characterized by physical and chemical tools (FT-IR, 1H NMR, 13C NMR, and Mass spectrometry). Moreover, all the novel synthesized derivatives were screened for their antihypertensive α-blocking efficacy against to assess their pharmaceutical significance. The encouraging promising results obtained from antihypertensive α-blocking activity studies on the newly synthesized derivatives make the synthesis of a new series of these compounds and studying of their pharmaceutical importance an active area for more and more investigations. The molecular docking of the most active derivative 15 b against the human dopamine D3 receptor was performed by the Molecular Operating Environment (MOE 2014. 0901) program.
HUDUDLARNI MUTANOSIB RIVOJLANISHINI TAʼMINLASHDAGI GLOBAL YONDASHUV VA STRATEGIYALAR
Creators: name: Mirsaidov, Shuxrat
name: Murtazaev., I.B
Publisher: name: Zenodo
Year: 2025

description: Hududlarni mutanosib rivojlantirish global miqyosda dolzarb masalalardan biri bo‘lib, mamlakatlar ijtimoiy-iqtisodiy taraqqiyotini ta’minlashda muhim ahamiyat kasb etadi. Ushbu maqolada hududiy rivojlanish jarayonlarini tartibga solishda qo‘llanilayotgan global yondashuv va strategiyalar tahlil qilingan. Dunyoda qo‘llanilayotgan zamonaviy konsepsiyalar, jumladan, barqaror rivojlanish, klasterlash, innovatsion infratuzilma yaratish hamda hududlararo integratsiyani kuchaytirish tamoyillari atroflicha o‘rganilgan. Maqolada turli mamlakatlar tajribasi asosida hududiy tafovutlarni kamaytirish strategiyalari va ularning samaradorligi tahlil qilinadi. Xususan, Yevropa Ittifoqi, AQSh, Xitoy va Janubi-Sharqiy Osiyo davlatlarining hududiy rivojlanish modellariga alohida e’tibor qaratilgan. Globalizatsiya sharoitida hududiy rivojlanishning innovatsion mexanizmlarini qo‘llash, jumladan, raqamli texnologiyalar va aqlli shaharlar konsepsiyasining hududiy rivojlanishga ta’siri muhokama qilingan. Shuningdek, rivojlanayotgan davlatlarda hududiy rivojlanish strategiyalarining moslashuvchanligi va ularning mahalliy sharoitga moslashtirish imkoniyatlari tahlil etilgan. Mahalliy resurslardan samarali foydalanish, davlat va xususiy sektor hamkorligi, barqaror iqtisodiy rivojlanish uchun investitsiyalar jalb qilish masalalari yoritilgan. Maqola hududiy muvozanatni ta’minlashga qaratilgan ilg‘or yondashuvlarni o‘rganishga xizmat qiladi va hududlarni samarali rivojlantirish bo‘yicha tavsiyalarni o‘z ichiga oladi.
Additional file 2 of Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus
Creators: name: Wang, Frank Qingyun
name: Dang, Xiao
name: Su, Huidong
name: Lei, Yao
name: She, Chun Hing
name: Zhang, Caicai
name: Chen, Xinxin
name: Yang, Xingtian
name: Yang, Jing
name: Feng, Hong
name: Yang, Wanling
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary Material 2: Supplementary Fig. 2. Correlation plots depict the expression of each TE subfamily in relation to the GSVA pathway (KEGG & REACTOME) score. The pathways exhibiting the highest average correlation with the 75 TEs are illustrated, with color indicating the R value derived from Pearson correlation.
title: A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast display
Creators: name: Schröter, Christian
name: Günther, Ralf
name: Rhiel, Laura
name: Becker, Stefan
name: Toleikis, Lars
name: Doerner, Achim
name: Becker, Janine
name: Schönemann, Andreas
name: Nasu, Daichi
name: Neuteboom, Berend
name: Kolmar, Harald
name: Hock, Björn
Publisher: name: Taylor & Francis
Year: 2025

description: There is growing interest in the fast and robust engineering of protein pH-sensitivity that aims to reduce binding at acidic pH, compared to neutral pH. Here, we describe a novel strategy for the incorporation of pH-sensitive antigen binding functions into antibody variable domains using combinatorial histidine scanning libraries and yeast surface display. The strategy allows simultaneous screening for both, high affinity binding at pH 7.4 and pH-sensitivity, and excludes conventional negative selection steps. As proof of concept, we applied this strategy to incorporate pH-dependent antigen binding into the complementary-determining regions of adalimumab. After 3 consecutive rounds of separate heavy and light chain library screening, pH-sensitive variants could be isolated. Heavy and light chain mutations were combined, resulting in 3 full-length antibody variants that revealed sharp, reversible pH-dependent binding profiles. Dissociation rate constants at pH 6.0 increased 230- to 780-fold, while high affinity binding at pH 7.4 in the sub-nanomolar range was retained. Furthermore, binding to huFcRn and thermal stability were not affected by histidine substitutions. Overall, this study emphasizes a generalizable strategy for engineering pH-switch functions potentially applicable to a variety of antibodies and further proteins-based therapeutics.
Scalar-isoscalar excitation in dense quark matter
Creators: name: Jaikumar, Prashanth
name: Zahed, Ismail
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the spectrum of scalar-isoscalar excitations in the color-flavor locked phase of dense quark matter. The sigma meson in this phase appears as a four-quark state (of diquark and anti-diquark) with a well-defined mass and extremely small width, as a consequence of it's small coupling to two pions. The quark particle/hole degrees of freedom also contribute significantly to the correlator just above the threshold 2Δwhere Δis the superconducting gap.
description: RevTeX, 11 pages, 4 figs
Additional file 3 of Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus
Creators: name: Wang, Frank Qingyun
name: Dang, Xiao
name: Su, Huidong
name: Lei, Yao
name: She, Chun Hing
name: Zhang, Caicai
name: Chen, Xinxin
name: Yang, Xingtian
name: Yang, Jing
name: Feng, Hong
name: Yang, Wanling
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary Material 3: Supplementary Fig. 3. TE expression is correlated with IFN level in SLE in an independent dataset (PRJNA476781). (A) Correlation between the three IFN expression modules and TE score in the integrated dataset (Left: M1.2, Middle: M3.4, Right: M5.12). (B) Bubble plot shows correlation between the expression of each TE subfamily with the three IFN modules of in the integrated dataset (Left: M1.2, Middle: M3.4, Right: M5.12). (C) Heatmap showcasing the correlation between the expression of each TE subfamily and the individual genes within the three IFN modules. (D) Scatter plot shows the correlation between the subfamily level TE expression and the expression level of three IFN modules is concordant in both integrated dataset and PRJNA476781.
The complications of learning from Super Soft Source X-ray spectra
Creators: name: Ness, Jan-Uwe
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Super Soft X-ray Sources (SSS) are powered by nuclear burning on the surface of an accreting white dwarf, they are seen around 0.1-1 keV (thus in the soft X-ray regime), depending on effective temperature and the amount of intervening interstellar neutral hydrogen N_H. The most realistic model to derive physical parameters from observed SSS spectra would be an atmosphere model that simulates the radiation transport processes. However, observed SSS high-resolution grating spectra reveal highly complex details that cast doubts on the feasibility of achieving unique results from atmosphere modeling. In this article, I discuss two independent atmosphere model analyses of the same data set, leading to different results. I then show some of the details that complicate the analysis and conclude that we need to approach the interpretation of high-resolution SSS spectra differently. We need to focus more on the data than the models and to use more phenomenological approaches as is traditionally done with optical spectra.
description: Accepted in JASR. 7 pages, 6 figure
Hubertia Robineau-Desvoidy 1863
Creators: name: Evenhuis, Neal L.
name: O'Hara, James E.
name: Pape, Thomas
name: Pont, Adrian C.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Hubertia

description: 246. Hubertia Robineau-Desvoidy, 1863b: 169.
 ORIGINALLY INCLUDED SPECIES: Hubertia elegans Robineau-Desvoidy, 1863.
 TYPE SPECIES: Hubertia elegans Robineau-Desvoidy, 1863, by original designation.
 CURRENT STATUS: Junior synonym of Bessa Robineau-Desvoidy, 1863 [teste Herting & Dely-Draskovits (1993: 142)].
FAMILY: TACHINIDAE.
description: Published as part of Evenhuis, Neal L., O'Hara, James E., Pape, Thomas & Pont, Adrian C., 2010, 2373, pp. 1-265 in Zootaxa 2373 on page 90
Ultraviolet images of Seyfert galaxies from the Optical Monitor on XMM-Newton
Creators: name: Blustin, A. J.
name: Branduardi-Raymont, G.
name: Breeveld, A.
name: Brinkman, A.
name: Kahn, S.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Optical Monitor telescope (Mason et al. 2001) on XMM-Newton provides an exciting multi-wavelength dimension to observations of Active Galactic Nuclei. Here we present ultraviolet images, taken with the OM UVW2 filter (140-270 nm), of various Seyfert galaxies, some of which have never been observed in this waveband before. The images show UV emission from both the active nucleus and the host galaxy. The distribution of UV emission in the galaxy shows where star formation is occurring, thus giving us clues as to the evolution of the host galaxy and perhaps its relationship to the Seyfert Nucleus.
description: 3 pages, 5 figures, to appear in ESA SP-488 (Proceeedings of the Estec Conference, New Visions of the X-ray Universe in the XMM-Newton and Chandra Era, September 2001), 2002
The Thomas precession and the transformation to rotating frames
Creators: name: Herrera, L.
name: Di Prisco, A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Thomas precession is calculated using three different transformations to the rotating frame. It is shown that for sufficiently large values of $v/c$, important differences in the predicted angle of precession appear, depending on the transformation used. For smaller values of $v/c$ these differences might be measured by extending the time of observation.
description: 12 pages Latex, 2 PS figures, to appear in Found.Phys. (Lett)
A New Fast Computation of a Permanent
Creators: name: Niu, Xuewei
name: Su, Shenghui
name: Zheng, Jianghua
name: Lü, Shuwang
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Complexity (cs.CC)
subject: FOS: Computer and information sciences

description: This paper proposes a general algorithm called Store-zechin for quickly computing the permanent of an arbitrary square matrix. Its key idea is storage, multiplexing, and recursion. That is, in a recursive process, some sub-terms which have already been calculated are no longer calculated, but are directly substituted with the previous calculation results. The new algorithm utilizes sufficiently computer memories and stored data to speed the computation of a permanent. The Analyses show that computating the permanent of an n * n matrix by Store-zechin requires (2^(n - 1)- 1)n multiplications and (2^(n-1))(n - 2)+ 1 additions while does (2^n - 1)n + 1 multiplications and (2^n - n)(n + 1)- 2 additions by the Ryser algorithm, and does (2^(n - 1))n + (n + 2) multiplications and (2^(n - 1))(n + 1)+ (n^2 - n -1) additions by the R-N-W algorithm. Therefore, Store-zechin is excellent more than the latter two algorithms, and has a better application prospect.
description: Unsuitable
Lathrobium stipiferum ASSING 2013
Creators: name: Assing, Volker
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Lathrobium
Lathrobium stipiferum

description: Lathrobium stipiferum ASSING, 2013 Material examined: China: Yunnan: 1 ex., Haba Shan, 27°21'N, 100°07'E, 3450 m, sifted, 24.VI.2012, leg. Grebennikov (cSme); 2 exs., Haba Shan, 27°22'N, 100°06'E, 3330 m, sifted, 23.VI.2012, leg. Grebennikov (CAS, cAss); 1 ex., Haba Shan, 27°22'N, 100°06'E, 3350 m, sifted, 23.VI.2012, leg. Grebennikov (cSme). Comment: This recently described species is endemic to the Haba Shan (ASSING 2013c).
description: Published as part of Assing, Volker, 2015, New species and additional records of Lathrobium and Elytrobium from the Palaearctic region, with special reference to the fauna of East Yunnan (Coleoptera: Staphylinidae: Paederinae), pp. 41-74 in Beiträge Zur Entomologie = Contributions to Entomology 65 (1) on page 49, DOI: 10.21248/contrib.entomol.65.1.41-74, http://zenodo.org/record/4753882
description: {"references": ["ASSING, V. 2013 c: On the Lathrobium fauna of China V. New species and additional records from Yunnan (Coleoptera: Staphylinidae: Paederinae). - Contributions to Entomology 63 (1): 53 - 128."]}
Hyalomya Robineau-Desvoidy 1830
Creators: name: Evenhuis, Neal L.
name: O'Hara, James E.
name: Pape, Thomas
name: Pont, Adrian C.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tachinidae
Hyalomya

description: 248. Hyalomya Robineau-Desvoidy, 1830: 298.
 ORIGINALLY INCLUDED SPECIES: Phasia atropurpurea Meigen, 1824 (as “ Phasia atro-pupurea. Meig.”); Phasia hamata Meigen, 1824 (as “ Phasia hamata. Latr. Meig.”); Thereva obesa Fabricius, 1798; Hyalomya basalis Robineau-Desvoidy, 1830; Phasia albipennis Meigen, 1824; Hyalomya nebulosa Robineau-Desvoidy, 1830; Hyalomya carbonaria Robineau-Desvoidy, 1830; Phasia pusilla Meigen, 1824 (as “ Phasia pusilla. Hoff. Meig.”); Hyalomya corinna Robineau-Desvoidy, 1830; Phasia hyalipennis Meigen, 1824 (as “ Phasia hyalipennis. Fallén. Meig,”); Phasia semicinerea Meigen, 1824 (as “ Phasia semi-cinerea. Meig.”).
 TYPE SPECIES: Phasia semicinerea Meigen, 1824 [= Phasia pusilla Meigen, 1824], by subsequent designation (Westwood, 1840: 140).
 CURRENT STATUS: Junior synonym of Phasia Meigen, 1824 [teste O’Hara & Wood (2004: 227)].
FAMILY: TACHINIDAE.
 REMARKS: Duponchel in d’Orbigny (1845b: 721) and Robineau-Desvoidy (1863b: 241) designated as type species Phasia atropurpurea Meigen, 1824 (the first of the twelve originally included species), but these were later.
 EMENDATIONS: Hyalomyia Macquart, 1834a: 205 (unjustified).
description: Published as part of Evenhuis, Neal L., O'Hara, James E., Pape, Thomas & Pont, Adrian C., 2010, 2373, pp. 1-265 in Zootaxa 2373 on page 90
Is sexual harassment and psychological abuse among medical students a fatality? A 2-year study in the Paris Descartes School of Medicine
Creators: name: Lisan, Quentin
name: Pigneur, Bénédicte
name: Pernot, Simon
name: Flahault, Cécile
name: Lenne, Frédéric
name: Friedlander, Gérard
name: Badoual, Cécile
name: Ranque, Brigitte
name: Lemogne, Cédric
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: An observatory of sexual harassment and psychological abuse was set up at one of France’s largest schools of medicine to both quantify and reduce sexual harassment or psychological abuse of medical students. Over a 2-year period, we described the evolution of sexual harassment and psychological abuse and explored for associated factors. Moreover, a qualitative analysis using an inductive approach was performed from students’ verbatim. 2795 responses were collected. Sexual harassment was reported in 7% and psychological abuse in 15%, at baseline, and decreased after the observatory was set up. Women had higher odds of being a victim of sexual harassment. Older students reported less often psychological abuse and being a witness of sexual harassment. Surgery departments were associated with up to 5.7-fold increased odds of sexual harassment. Surgery and pediatrics departments were associated with a 2-fold increased odds of psychological abuse. Qualitative analysis revealed four categories: humiliation, the feeling of inferiority, sexual harassment, and manifestations of violence. During clerkships, factors associated with higher odds of sexual harassment and psychological abuse were female gender, younger age, and departments of surgery. Setting up such an observatory may contribute to reduce this burden and provide a useful tool to raise awareness.
Comparative Proteomics in Rice Seedlings to Characterize the Resistance to Cadmium Stress by High-Performance Liquid Chromatography – Tandem Mass Spectrometry (HPLC-MS/MS) with Isobaric Tag for Relative and Absolute Quantitation (iTRAQ)
Creators: name: Sanxiong Liu
name: Yongchao Li
name: Licheng Liu
name: Min, Jun
name: Wenqiang Liu
name: Xiaoxiang Li
name: Xiaowu Pan
name: Xiangyang Lu
name: Qiyun Deng
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Cadmium (Cd) is a heavy metal used in industrial processes that impedes the growth of plants. Although intensive work has concentrated on the mechanism of rice under Cd stress, few studies compared the proteomic information on the mechanism between different cultivars. Different rice cultivars were screened and two cultivars, the japonica cultivar Bancanggengnuo (BCGN) and indica cultivar Yuzhenxiang (YZX) were selected to be the varieties for proteomic experiments. High-performance liquid chromatography – tandem mass spectrometry (HPLC-MS/MS) with an isobaric tag for relative and absolute quantitation (iTRAQ) was used to analyze the global protein profiles of these two cultivars. There were 109 and 209 differentially expressed proteins (DEPs) in the Cd treatment groups for BCGN and YZX respectively and 61 additional DEPs between cultivars after treatment. Pathway enrichment analysis showed that three pathways were altered in the cultivars, which affected photosynthesis and redox reactions. A total of 37 up- and 27 down-regulated proteins were identified in both cultivars exposed to Cd. The molecular regulatory network revealed that several proteins associated with carbohydrate metabolism, redox reaction and signal transduction were involved in and acted as the intersection point of disturbed metabolism. This is the first report on the comprehensive proteomic characterization of Cd-exposed leaf proteomes in rice. These findings may facilitate the unraveling molecular mechanism underlying Cd stress response in rice, and provide fundamental insights into the development of Cd-resistant rice cultivars. This work has explored the mechanism of Cd resistance at the protein level, which may be a novel target for improving the resistance of rice to this heavy metal.
Hydromya Robineau-Desvoidy 1830
Creators: name: Evenhuis, Neal L.
name: O'Hara, James E.
name: Pape, Thomas
name: Pont, Adrian C.
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Sciomyzidae
Hydromya

description: 251. Hydromya Robineau-Desvoidy, 1830: 691.
 ORIGINALLY INCLUDED SPECIES: Hydromya caeruleipennis Robineau-Desvoidy, 1830; Hydromya rubicunda Robineau-Desvoidy, 1830.
 TYPE SPECIES: Hydromya caeruleipennis Robineau-Desvoidy, 1830 [= Musca dorsalis Fabricius, 1775], by subsequent designation (Rozkošný & Elberg, 1984: 183).
 CURRENT STATUS: Valid genus [teste Rozkošný & Elberg (1984: 183)].
FAMILY: SCIOMYZIDAE.
 EMENDATIONS: Hydromyia Curtis, 1837: 280 (unjustified), n. syn.; Hydromyia Agassiz, 1846b: 188 (unjustified).
description: Published as part of Evenhuis, Neal L., O'Hara, James E., Pape, Thomas & Pont, Adrian C., 2010, 2373, pp. 1-265 in Zootaxa 2373 on page 91
Time dependent photoionization opacities in dense Gamma-Ray Burst environments
Creators: name: Lazzati, Davide
name: Perna, Rosalba
name: Ghisellini, Gabriele
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The recent detection of a transient absorption feature in the X-ray prompt emission of GRB 990705 showed the importance of such observations in the understanding of gamma-ray bursts and their progenitors. We investigate the time dependence of photoionization edges during the prompt emission of bursts in different environments. We show that their variability can be used to infer the density and geometry of the surrounding medium, giving important clues to unveil the nature of the burst progenitor.
description: 5 pages, 4 postscript figures, MNRAS in press
CBCS Assay Development Guideline
Creators: name: Chemical Biology Consortium Sweden (CBCS)
Publisher: name: Zenodo
Year: 2025
Subjects: Assay design
Assay Development
Assay optimization
Biochemical Assays
Cell-Based Assays
Z'-Factor Analysis
Assay Validation
Detection Methods

description: Unique assays developed in relevant biological environments are the first step toward investigating small molecules. At CBCS, we provide collaborative and supportive services to design and enhance robust assays that meet specific research needs. Whether it involves creating accurate biochemical assays or utilizingsophisticated cell-based models, CBCS offers the necessary tools for successful hit identification. Specializing in adapting bioassays for high-throughput applications, we assist assay transfer from laboratory settings to microtiter-based formats and enable robust screening in 96-, 384-, and 1536-well plates using automation.

This document provides stepwise guidelines of assay development process, which includes crucial and practical information for setting up an assay toward high throughput screening (HTS) applications. Tips and tricks are summarized from our experience in creating successful HTS assays.