cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quand donner la vie bascule dans la folie!
Creators: name: Hostettler, Sophie
name: Pomorski, Maroussia
Publisher: name: Unknown
Year: 0
Subjects: subject: santé mentale
subject: psychiatrie
subject: accouchement
subject: femme
subject: maternité
subject: traumatologie
subject: psychose

description: Donner la vie est un merveilleux moment pour de nombreuses femmes, mais la période du postpartum est parfois aussi un moment vulnérable pour les maladies psychiatriques. À travers cette revue de littérature, nous chercherons à savoir quel est le rôle infirmier auprès de femmes souffrant de psychose puerpérale (PPP) dans une unité mère-enfant, dans le but de favoriser leurs compétences maternelles.
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
Uni-layer magnets: a new concept for LTS and HTS based superconducting magnets
Creators: name: Fernández, José Luis Rudeiros
name: Ferracin, Paolo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: A novel geometrical configuration to form a magnetic field perpendicular to an aperture, created by an asymmetric current distribution, within a single layer, and using a continuous ideal current line, named the uni-layer magnet, is here presented. The idea is compared to existing concepts in superconducting magnets, namely, the $\cosθ$ sector magnet, stress managed $\cosθ$ and canted $\cosθ$. The uni-layer magnet allows for a design with a continuous unit length (no layer jump), and an increased minimum bending radius of the conductor in relation to traditional $\cosθ$ and canted $\cosθ$ designs. The specific characteristics of the uni-layer design are especially advantageous for strain-sensitive and prone to winding degradation high-temperature superconductors, in very high field accelerator magnet applications, in which, high efficiency in the use of conductor, and a small aperture are required. The advantages with regard to the design and fabrication of uni-layer magnets in relation to other concepts are also discussed.
description: 17 pages, submitted to IOP's Superconductor Science and Technology Journal (SuST)
Two Distinct Gamma Interferon-Inducible Promoters of the Major Histocompatibility Complex Class II Transactivator Gene Are Differentially Regulated by STAT1, Interferon Regulatory Factor 1, and Transforming Growth Factor β
Creators: name: Piskurich, Janet F.
name: Wang, Ying
name: Linhoff, Michael W.
name: Ting, Jenny P.-Y.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: The major histocompatibility complex (MHC) class II transactivator (CIITA) is the master regulatory factor required for appropriate expression of class II MHC genes. Understanding the expression of CIITA is key to understanding the regulation of class II MHC genes. This report describes the independent regulation of two distinct CIITA promoters by cytokines with opposing functions, gamma interferon (IFN-γ) and transforming growth factor β (TGF-β). A functional analysis of deletion mutations of the upstream promoter (promoter III) identified an IFN-γ-responsive region located approximately 5 kb from the transcriptional start site. An in vivo DNase I hypersensitivity analysis detected a hypersensitive site in this area which supports the relevance of this region. When the downstream promoter (promoter IV) was studied by in vivo genomic footprinting, IFN-γ-induced changes at putative binding sites for STAT1, interferon regulatory factor 1 (IRF-1), and E-box proteins were seen. Gel shift and supershift analyses for IRF-1 confirmed the in vivo footprint results. The role of the IFN-γ-inducible transcription factor STAT1 was examined functionally. Although both promoters were controlled by STAT1, promoter-specific regulation was exhibited. The IFN-γ response of promoter III was completely dependent on STAT1 and not IRF-1, while promoter IV was partially activated by IRF-1 in the total absence of STAT1 expression. While both promoters were affected by TGF-β, activation of promoter III by IFN-γ was more severely diminished by TGF-β treatment. The differential control of CIITA promoters by TGF-β, IRF-1, and STAT1 may be important in refining regulation of class II MHC genes in different cell types and under different stimulatory conditions.
Voids in Modified Gravity Reloaded: Eulerian Void Assignment
Creators: name: Lam, Tsz Yan
name: Clampitt, Joseph
name: Cai, Yan-Chuan
name: Li, Baojiu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We revisit the excursion set approach to calculate void abundances in chameleon-type modified gravity theories, which was previously studied by Clampitt, Cai and Li (2013). We focus on properly accounting for the void-in-cloud effect, i.e., the growth of those voids sitting in over-dense regions may be restricted by the evolution of their surroundings. This effect may change the distribution function of voids hence affect predictions on the differences between modified gravity and GR. We show that the thin-shell approximation usually used to calculate the fifth force is qualitatively good but quantitatively inaccurate. Therefore, it is necessary to numerically solve the fifth force in both over-dense and under-dense regions. We then generalise the Eulerian void assignment method of Paranjape, Lam and Sheth (2012) to our modified gravity model. We implement this method in our Monte Carlo simulations and compare its results with the original Lagrangian methods. We find that the abundances of small voids are significantly reduced in both modified gravity and GR due to the restriction of environments. However, the change in void abundances for the range of void radii of interest for both models is similar. Therefore, the difference between models remains similar to the results from the Lagrangian method, especially if correlated steps of the random walks are used. As Clampitt, Cai and Li (2013), we find that the void abundance is much more sensitive to modified gravity than halo abundances. Our method can then be a faster alternative to N-body simulations for studying the qualitative behaviour of a broad class of theories. We also discuss the limitations and other practical issues associated with its applications.
description: 12 pages, 7 figures
Interactions of Charged Spin-2 Fields
Creators: name: de Rham, Claudia
name: Matas, Andrew
name: Ondo, Nicholas
name: Tolley, Andrew J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In light of recent progress in ghost-free theories of massive gravity and multi-gravity, we reconsider the problem of constructing a ghost-free theory of an interacting spin-2 field charged under a U(1) gauge symmetry. Our starting point is the theory originally proposed by Federbush, which is essentially Fierz-Pauli generalized to include a minimal coupling to a U(1) gauge field. We show the Federbush theory with a dynamical U(1) field is in fact ghost-free and can be treated as a healthy effective field theory to describe a massive charged spin-2 particle. It can even potentially have healthy dynamics above its strong-coupling scale. We then construct candidate gravitational extensions to the Federbush theory both by using Dimensional Deconstruction, and by constructing a general non-linear completion. However, we find that the U(1) symmetry forces us to modify the form of the Einstein-Hilbert kinetic term. By performing a constraint analysis directly in the first-order form, we show that these modified kinetic terms inevitably reintroduce the Boulware-Deser ghost. As a by-product of our analysis, we present a new proof for ghost-freedom of bi-gravity in 2+1 dimensions (also known as Zwei-Dreibein gravity). We also give a complementary algebraic argument that the Einstein-Hilbert kinetic term is incompatible with a U(1) symmetry, for a finite number of gravitons.
Quand on ne peut rajouter de jours à la vie …
Creators: name: Hajdari, Merita
name: Thuraisingam, Venusha
name: Vo, Nhu-Linh
Publisher: name: Unknown
Year: 0
Subjects: subject: soins palliatifs
subject: pédiatrie
subject: mort
subject: accompagnement
subject: parentalité
subject: enfant
subject: relation soignants-soigné
subject: fin de vie

description: Dans le but d’aider les parents à traverser au mieux la phase terminale de leur enfant atteint de maladie mortelle, cette revue de littérature tente d’identifier les besoins de ces parents, dans le contexte des soins palliatifs pédiatriques.
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
Strategies for variational quantum compiling of a zero-phase beamsplitter on the Xanadu X8 processor
Creators: name: Volkoff, T. J.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In the context of variational compiling of a continuous-variable (CV) unitary operation, the architecture and parameter space of the Xanadu X8 processor constrain both the set of feasible compiling problems and the allowed cost functions. In this paper, we motivate a faithful cost function for variational compiling of a two-mode, continuous-variable beamsplitter gate with real matrix elements (i.e., a "zero-phase" beamsplitter) that complies with the constraints of the X8 processor. This cost function is then computed on the X8. Despite the noise in the processor, we find that the cost function exhibits optimum parameter resilience and, therefore, that this variational compiling problem is feasible on the X8. The intent of the paper is partly to report a proof-of-principle cost function calculation on near-term CV hardware, and partly to present methods that may be relevant for CV variational compiling problems in more complicated, large scale settings.
description: 12 pages, 3 figures
Les douleurs fantômes : comment soigner l'invisible ?
Creators: name: Goumaz, Marc
name: Rouiller, Christelle
Publisher: name: Unknown
Year: 0
Subjects: subject: amputation
subject: douleur
subject: thérapeutique
subject: rôle infirmier

description: But de la revue de littérature : Avec l’augmentation de pathologies entrainant l’amputation d’un membre, le phénomène de douleurs fantômes est déjà bien présent dans les soins. Ayant tous deux été confrontés à cette problématique lors de nos stages, il nous semblait important de revenir sur ces douleurs particulières, mais surtout sur les actions que nous pourrions mettre en place en tant que future infirmière et infirmier. Le but de cette revue de littérature est alors de mettre en lumière quelles sont les interventions que l’infirmière peut mettre en place de manière autonome, afin de soulager les douleurs fantômes du patient.
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
RG Flows and Symmetry Enhancement in Five-Dimensional Lifshitz Gauge Theories
Creators: name: Lambert, Neil
name: Smith, Joseph
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Lagrangian gauge theories with a z=2 Lifshitz scaling provide a family of interacting, asymptotically free five-dimensional field theories. We examine some of their quantum properties, extending previous results to include matter. We present no-go theorems that, in the absence of constraints, such theories cannot admit a spinorial supersymmetry or a boost symmetry. However, we argue that there exist renormalization group flows whose fixed points can admit supersymmetry and boosts, i.e. super-Schrodinger symmetry. We also present examples of Lifshitz gauge theories with a scalar supersymmetry.
description: Minor corrections and some improved explanations. Version to appear in JHEP
Conduction in low Mach number flows: Part I Linear & weakly nonlinear regimes
Creators: name: Lecoanet, Daniel
name: Brown, Benjamin P.
name: Zweibel, Ellen G.
name: Burns, Keaton J.
name: Oishi, Jeffrey S.
name: Vasil, Geoffrey M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Thermal conduction is an important energy transfer and damping mechanism in astrophysical flows. Fourier's law - the heat flux is proportional to the negative temperature gradient, leading to temperature diffusion - is a well-known empirical model of thermal conduction. However, entropy diffusion has emerged as an alternative thermal conduction model, despite not ensuring the monotonicity of entropy. This paper investigates the differences between temperature and entropy diffusion for both linear internal gravity waves and weakly nonlinear convection. In addition to simulating the two thermal conduction models with the fully compressible Navier-Stokes equations, we also study their effects in the reduced, "sound-proof" anelastic and pseudo-incompressible equations. We find that in the linear and weakly nonlinear regimes, temperature and entropy diffusion give quantitatively similar results, although there are some larger errors in the pseudo-incompressible equations with temperature diffusion due to inaccuracies in the equation of state. Extrapolating our weakly nonlinear results, we speculate that differences between temperature and entropy diffusion might become more important for strongly turbulent convection.
description: 17 pages, accepted to ApJ
Understanding Forbush decrease drivers based on shock-only and CME-only models using global signature of February 14, 1978 event
Creators: name: Raghav, Anil
name: Bhaskar, Ankush
name: Lotekar, Ajay
name: Vichare, Geeta
name: Yadav, Virendra
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We have studied Forbush decrease (FD) event occurred on February 14, 1978 using 43 neutron monitor observatories to understand the global signature of FD. We have studied rigidity dependence of shock amplitude and total FD amplitude. We have found almost the same power law index for both shock phase amplitude and total FD amplitude. Local time variation of shock phase amplitude and maximum depression time of FD have been investigated which indicate possible effect of shock/CME orientation. We have analyzed rigidity dependence of time constants of two phase recovery. Time constants of slow component of recovery phase show rigidity dependence and implies possible effect of diffusion. Solar wind speed was observed to be well correlated with slow component of FD recovery phase. This indicates solar wind speed as possible driver of recovery phase. To investigate the contribution of interplanetary drivers, shock and CME in FD, we have used shock-only and CME-only models. We have applied these models separately to shock phase and main phase amplitudes respectively. This confirms present accepted physical scenario that the first step of FD is due to propagating shock barrier and second step is due to flux rope of CME/magnetic cloud.
description: 24 pages, 11 figures
Algorithmic Fairness Datasets: the Story so Far
Creators: name: Fabris, Alessandro
name: Messina, Stefano
name: Silvello, Gianmaria
name: Susto, Gian Antonio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Data-driven algorithms are studied in diverse domains to support critical decisions, directly impacting people's well-being. As a result, a growing community of researchers has been investigating the equity of existing algorithms and proposing novel ones, advancing the understanding of risks and opportunities of automated decision-making for historically disadvantaged populations. Progress in fair Machine Learning hinges on data, which can be appropriately used only if adequately documented. Unfortunately, the algorithmic fairness community suffers from a collective data documentation debt caused by a lack of information on specific resources (opacity) and scatteredness of available information (sparsity). In this work, we target data documentation debt by surveying over two hundred datasets employed in algorithmic fairness research, and producing standardized and searchable documentation for each of them. Moreover we rigorously identify the three most popular fairness datasets, namely Adult, COMPAS and German Credit, for which we compile in-depth documentation. This unifying documentation effort supports multiple contributions. Firstly, we summarize the merits and limitations of Adult, COMPAS and German Credit, adding to and unifying recent scholarship, calling into question their suitability as general-purpose fairness benchmarks. Secondly, we document and summarize hundreds of available alternatives, annotating their domain and supported fairness tasks, along with additional properties of interest for fairness researchers. Finally, we analyze these datasets from the perspective of five important data curation topics: anonymization, consent, inclusivity, sensitive attributes, and transparency. We discuss different approaches and levels of attention to these topics, making them tangible, and distill them into a set of best practices for the curation of novel resources.
description: Published in Data Mining and Knowledge Discovery https://doi.org/10.1007/s10618-022-00854-z
A la rencontre de mon patient, cet être humain si singulier hospitalisé
Creators: name: Gabriel, Laura
name: Medina, Fanny
Publisher: name: Unknown
Year: 0
Subjects: subject: caring
subject: relation soignant-soigné
subject: satisfaction
subject: patient
subject: qualité des soins

description: Les situations de soins évoluent et deviennent de plus en plus complexes. Les besoins des patients se diversifient et l’infirmière doit faire face à de nouvelles préoccupations. Les exigences des milieux hospitaliers changent : la meilleure qualité au moindre coût, le meilleur soin dans un minimum de temps et aux moindres frais. Tout est protocolaire et s’effectue sous une forte pression économique et temporelle. Où est la dimension humaine dans ce système qui accorde une place prépondérante aux tâches mesurables, visibles et aux check-lists sans fin? Le quotidien des infirmières semble de plus en plus difficile et nous nous demandons de quoi notre avenir d’infirmière sera fait. Nous nous intéressons, dans ce travail, au milieu somatique aigu (médecine, chirurgie, soins intensifs, …) de manière générale et nous avons comme population cible les adultes, de 18 à 90 ans. Le contexte actuel est considéré comme rationalisé et standardisé avec un accent de performance et d’efficience. L’être humain est vu comme unique et singulier, comme un individu. Le soin humain est considéré à travers le care et les soins individualisés et centrés sur la personne. La question est mise en lien avec la qualité des soins aux patients.
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
A Cognitive Routing framework for Self-Organised Knowledge Defined Networks
Creators: name: Ghosh, Saptarshi
Publisher: name: London South Bank University
Year: 2022

description: This study investigates the applicability of machine learning methods to the routing protocols for achieving rapid convergence in self-organized knowledge-defined networks. The research explores the constituents of the Self-Organized Networking (SON) paradigm for 5G and beyond, aiming to design a routing protocol that complies with the SON requirements. Further, it also exploits a contemporary discipline called Knowledge-Defined Networking (KDN) to extend the routing capability by calculating the “Most Reliable” path than the shortest one. The research identifies the potential key areas and possible techniques to meet the objectives by surveying the state-of-the-art of the relevant fields, such as QoS aware routing, Hybrid SDN architectures, intelligent routing models, and service migration techniques. The design phase focuses primarily on the mathematical modelling of the routing problem and approaches the solution by optimizing at the structural level. The work contributes Stochastic Temporal Edge Normalization (STEN) technique which fuses link and node utilization for cost calculation; MRoute, a hybrid routing algorithm for SDN that leverages STEN to provide constant-time convergence; Most Reliable Route First (MRRF) that uses a Recurrent Neural Network (RNN) to approximate route-reliability as the metric of MRRF. Additionally, the research outcomes include a cross-platform SDN Integration framework (SDN-SIM) and a secure migration technique for containerized services in a Multi-access Edge Computing environment using Distributed Ledger Technology. The research work now eyes the development of 6G standards and its compliance with Industry-5.0 for enhancing the abilities of the present outcomes in the light of Deep Reinforcement Learning and Quantum Computing.
Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-kappa B
Creators: name: Mayo, M. W.
name: Baldwin, A. S.
name: Wang, C.-Y.
name: Madrid, L. V.
name: Schottelius, A. J. G.
name: Guttridge, D. C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: It is well established that cell survival signals stimulated by growth factors, cytokines, and oncoproteins are initiated by phosphoinositide 3-kinase (PI3K)- and Akt-dependent signal transduction pathways. Oncogenic Ras, an upstream activator of Akt, requires NF-κB to initiate transformation, at least partially through the ability of NF-κB to suppress transformation-associated apoptosis. In this study, we show that oncogenic H-Ras requires PI3K and Akt to stimulate the transcriptional activity of NF-κB. Activated forms of H-Ras and MEKK stimulate signals that result in nuclear translocation and DNA binding of NF-κB as well as stimulation of the NF-κB transactivation potential. In contrast, activated PI3K or Akt stimulates NF-κB-dependent transcription by stimulating transactivation domain 1 of the p65 subunit rather than inducing NF-κB nuclear translocation via IκB degradation. Inhibition of IκB kinase (IKK), using an IKKβ dominant negative protein, demonstrated that activated Akt requires IKK to efficiently stimulate the transactivation domain of the p65 subunit of NF-κB. Inhibition of endogenous Akt activity sensitized cells to H-Ras(V12)-induced apoptosis, which was associated with a loss of NF-κB transcriptional activity. Finally, Akt-transformed cells were shown to require NF-κB to suppress the ability of etoposide to induce apoptosis. Our work demonstrates that, unlike activated Ras, which can stimulate parallel pathways to activate both DNA binding and the transcriptional activity of NF-κB, Akt stimulates NF-κB predominantly by upregulating of the transactivation potential of p65.
La peau, reflet de soi
Creators: name: Dos Santos Pêgo, Myriam
name: Turin, Lucie
Publisher: name: Unknown
Year: 0
Subjects: subject: accompagnement
subject: rôle infirmier
subject: brûlure
subject: réadaptation
subject: psychosociologie

description: La présente revue de littérature est centrée sur l’accompagnement infirmier en milieu hospitalier auprès d’adultes atteints de brûlures dans le but de favoriser leur réadaptation psychosociale, ceci en se concentrant sur l’image corporelle. De nombreuses études autour de la thématique de la brûlure se concentrent sur la douleur de cette population, ou encore sur la population pédiatrique touchée par cette problématique. Or, d’un point de vu holistique, il semble essentiel de s’intéresser à la sphère psychosociale de la personne ainsi qu’aux conséquences de la brûlure sur celle-ci. Plusieurs études montrent qu’il y a parfois un manque de connaissances dans ce domaine et qu’il est primordial de s’intéresser au vécu du patient et à l’impact de sa brûlure pour favoriser un état de mieux-être psychosocial.
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
Arginine-Rich Regions Mediate the RNA Binding and Regulatory Activities of the Protein Encoded by the Drosophila melanogaster suppressor of sable Gene
Creators: name: Bai, W.-L.
name: Brewer-Jensen, P.
name: Turnage, M. A.
name: Searles, L. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: The Drosophila melanogaster suppressor of sable gene, su(s), encodes a novel, 150-kDa nuclear RNA binding protein, SU(S), that negatively regulates RNA accumulation from mutant alleles of other genes that have transposon insertions in the 5′ transcribed region. In this study, we delineated the RNA binding domain of SU(S) and evaluated its relevance to SU(S) function in vivo. As a result, we have defined two arginine-rich motifs (ARM1 and ARM2) that mediate the RNA binding activity of SU(S). ARM1 is required for in vitro high-affinity binding of SU(S) to small RNAs that were previously isolated by SELEX (binding site selection assay) and that contain a common consensus sequence. ARM1 is also required for the association of SU(S) with larval polytene chromosomes in vivo. ARM2 promotes binding of SU(S) to SELEX RNAs that lack the consensus sequence and apparently is neither necessary nor sufficient for the stable polytene chromosome association of SU(S). Use of the GAL4/UAS system to drive ectopic expression of su(s) cDNA transgenes revealed two previously unknown properties of SU(S). First, overexpression of SU(S) is lethal. Second, SU(S) negatively regulates expression of su(s) intronless cDNA transgenes, and the ARMs are required for this effect. Considering these and previous results, we propose that SU(S) binds to the 5′ region of nascent transcripts and inhibits RNA production in a manner that can be overcome by splicing complex assembly.
Five Facets of 6G: Research Challenges and Opportunities
Creators: name: Shen, Li-Hsiang
name: Feng, Kai-Ten
name: Hanzo, Lajos
Publisher: name: arXiv
Year: 2022
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Whilst the fifth-generation (5G) systems are being rolled out across the globe, researchers have turned their attention to the exploration of radical next-generation solutions. At this early evolutionary stage we survey five main research facets of this field, namely {\em Facet~1: next-generation architectures, spectrum and services, Facet~2: next-generation networking, Facet~3: Internet of Things (IoT), Facet~4: wireless positioning and sensing, as well as Facet~5: applications of deep learning in 6G networks.} In this paper, we have provided a critical appraisal of the literature of promising techniques ranging from the associated architectures, networking, applications as well as designs. We have portrayed a plethora of heterogeneous architectures relying on cooperative hybrid networks supported by diverse access and transmission mechanisms. The vulnerabilities of these techniques are also addressed and carefully considered for highlighting the most of promising future research directions. Additionally, we have listed a rich suite of learning-driven optimization techniques. We conclude by observing the evolutionary paradigm-shift that has taken place from pure single-component bandwidth-efficiency, power-efficiency or delay-optimization towards multi-component designs, as exemplified by the twin-component ultra-reliable low-latency mode of the 5G system. We advocate a further evolutionary step towards multi-component Pareto optimization, which requires the exploration of the entire Pareto front of all optiomal solutions, where none of the components of the objective function may be improved without degrading at least one of the other components.
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: What awaits Malvolio after the conclusion of William Shakespeare’s Twelfth Night is a contentious topic in scholarship. Some scholars, such as Marjorie Garber, contend that he is the sole character excluded from the comedy’s joyous ending, while others, such as Alastair Fowler, contend that the play suggests an ultimate reconciliation. This essay will contend that Shakespeare deliberately leaves Malvolio’s destiny ambiguous and undecidable. Drawing from historical texts such as John Calvin’s works and the Geneva Bible, it will argue that Twelfth Night attacks the Puritans, who themselves often attacked the institution of the theatre and opposed such festal occasions as Epiphany, which the play celebrates. The comedy accomplishes this attack by subverting a key Puritan doctrine: double predestination. Malvolio’s potential exclusion or inclusion at the concluding wedding feast, following biblical imagery, becomes symbolic of reprobation and election. As Malvolio’s character is left thoroughly ambiguous throughout the play, and as the play ends with Olivia’s offer of reconciliation to Malvolio—which is neither accepted nor rejected within the play itself—the emphasis is placed upon Malvolio’s free will to determine his future, and, by extension, his eschatological state. Hence, the cost of the Puritan’s symbolic redemption is his very Puritanism.
Dimensional Reduction in 6D Standing Waves Braneworld
Creators: name: Sakhelashvili, Otari
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We found cosmological solution of the 6D standing wave braneworld model generated by gravity coupled to a massless scalar phantom-like field. By obtaining a full exact solution of the model we found a novel dynamical mechanism in which the anisotropic nature of the primordial metric gives rise to expansion of three spatial brane dimensions and affectively reduction of other spatial directions. This dynamical mechanism can be relevant for dimensional reduction in string and other higher dimensional theories in the attempt of getting a 4D isotropic expanding space-time.
description: arXiv admin note: text overlap with arXiv:1202.1608 by other authors
Le délirium hyperactif de la personne âgée
Creators: name: Di Biase, Debora
name: Nguyen, Christian
Publisher: name: Unknown
Year: 0
Subjects: subject: personne âgée, délirium
subject: psychogériatrie
subject: rôle infirmier
subject: accompagnement

description: « Je ne sais plus où j’en suis. Qu’est-ce que vous faites ? », « Calmez-vous ! Vous êtes confuse, ça passera ! » Qui n’a jamais entendu ce genre de propos de la part du personnel soignant envers un patient qui semble agité et désorienté ? Le phénomène de délirium constitue un réel problème de santé publique et, plus particulièrement auprès des personnes âgées. Avec des répercussions non négligeables sur la qualité de vie, le délirium chez la personne âgée est souvent sousestimé et les infirmières, ainsi que les médecins, rencontrent des difficultés quant à sa détection. L’objectif de notre travail de Bachelor consiste à une revue documentaire visant à proposer des recommandations spécifiques au rôle infirmier. Chez la personne âgée de 65 ans et plus manifestant un délirium hyperactif dans le contexte hospitalier, quelle est la contribution de l’infirmière dans la prévention secondaire et la gestion des symptômes? Guidés par les concepts relatifs à la théorie de gestion des symptômes, nous avons utilisé deux bases de données : CINAHL et NCBI pubmed. Nous avons inclus dans ces bases de données les critères propres à la personne âgée de 65 ans et plus, ainsi que les publications comprises entre 2004 et 2014. Ce travail exclut les contextes liés aux soins palliatifs, aux soins intensifs et les soins à domicile, ainsi que le délirium surajouté à la démence. Neuf articles scientifiques ont été retenus, dont deux revues de littératures systématiques. Les infirmières ont un rôle primordial dans la détection et la prévention du délirium. Sous sa forme hyperactive, l’utilisation de la Confusion Assessment Method (CAM) constitue un outil de choix associé au Nursing Delirium Scale (Nu-DESC).
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
Dissection of Ras-Dependent Signaling Pathways Controlling Aggressive Tumor Growth of Human Fibrosarcoma Cells: Evidence for a Potential Novel Pathway
Creators: name: Plattner, R.
name: Der, C. J.
name: Gupta, S.
name: Stanbridge, E. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: Activation of multiple signaling pathways is required to trigger the full spectrum of in vitro and in vivo phenotypic traits associated with neoplastic transformation by oncogenic Ras. To determine which of these pathways are important for N-ras tumorigenesis in human cancer cells and also to investigate the possibility of cross talk among the pathways, we have utilized a human fibrosarcoma cell line (HT1080), which contains an endogenous mutated allele of the N-ras gene, and its derivative (MCH603c8), which lacks the mutant N-ras allele. We have stably transfected MCH603c8 and HT1080 cells with activating or dominant-negative mutant cDNAs, respectively, of various components of the Raf, Rac, and RhoA pathways. In previous studies with these cell lines we showed that loss of mutant Ras function results in dramatic changes in the in vitro phenotypic traits and conversion to a weakly tumorigenic phenotype in vivo. We report here that only overexpression of activated MEK contributed significantly to the conversion of MCH603c8 cells to an aggressive tumorigenic phenotype. Furthermore, we have demonstrated that blocking the constitutive activation of the Raf-MEK, Rac, or RhoA pathway alone is not sufficient to block the aggressive tumorigenic phenotype of HT1080, despite affecting a number of in vitro-transformed phenotypic traits. We have also demonstrated the possibility of bidirectional cross talk between the Raf-MEK-ERK pathway and the Rac-JNK or RhoA pathway. Finally, overexpression of activated MEK in MCH603c8 cells appears to result in the activation of an as-yet-unidentified target(s) that is critical for the aggressive tumorigenic phenotype.
Un dernier maessage…
Creators: name: Desgalier, Aurélia
name: Novak, Theresa
Publisher: name: Unknown
Year: 0
Subjects: subject: soins palliatifs
subject: médecine complémentaire
subject: maladie incurable
subject: massage
subject: qualité de vie

description: Après ces trois années de formation, nous avons développé un intérêt particulier pour le domaine des soins palliatifs et les médecines complémentaires. Nos expériences durant les stages nous ont montré la difficulté des prises en charge de patients souffrant de pathologies incurables. Durant nos prestations de soins, nous avons pu constater auprès de plusieurs patients, l’importance du massage. En effet, à plusieurs reprises cette demande a été évoquée. C’est pourquoi, nous voulons apporter une contribution à cette offre en soins. Les soins palliatifs sont en plein développement en Suisse, depuis la création de la Société Suisse de Médecine Palliative en 1988. De plus, en 2009, la Confédération Helvétique a mis en place la première stratégie nationale afin d’incorporer les soins palliatifs dans le système de santé Suisse. En effet, selon la Revue médicale suisse, en 2011, « le cancer est responsable de 30% des décès chez les hommes et de 23% chez les femmes, ce qui en fait la deuxième cause de décès en Suisse. » (Di Silvestro, Pugliesi, Pautex, 2011).
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
title: Electroconvulsivothérapie et accompagnement infirmier
title: il y a de l'électricité dans l'air…
titleType: Subtitle
Creators: name: Da Costa Oliveira, Helena
name: Fauchère, Isabelle
Publisher: name: Unknown
Year: 0
Subjects: subject: électroconvulsivothérapie
subject: électrochocs
subject: thérapie
subject: psychiatrie
subject: dépression

description: Pendant notre stage en psychiatrie, nous avons été confrontées à la thérapie par électrochocs : l’électroconvulsivothérapie (ECT). Ce traitement controversé divise l’opinion publique de par son contexte historique, son mécanisme d’action encore mystérieux et les effets secondaires difficiles à supporter. Cependant, l’ECT apporte des effets bénéfiques aux patients souffrant de dépression sévère, là où les traitements pharmacologiques ont échoué. Malgré cela, les divergences de ce traitement au sein de l’équipe remettent en question la prise en soin du patient.
description: Mémoire de bachelor : Haute école de la santé La Source, 2014
DNA Damage in the Nucleosome Core Is Refractory to Repair by Human Excision Nuclease
Creators: name: Mo, J.
name: Hara, R.
name: Sancar, A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: To investigate the effect of nucleosomes on nucleotide excision repair in humans, we prepared a mononucleosome containing a (6-4) photoproduct in the nucleosome core and examined its repair with the reconstituted human excision nuclease system and with cell extracts. Nucleosomal DNA is repaired at a rate of about 10% of that for naked DNA in both systems. These results are in agreement with in vivo data showing a considerably slower rate of repair of overall genomic DNA relative to that for transcriptionally active DNA. Furthermore, our results indicate that the first-order packing of DNA in nucleosomes is a primary determinant of slow repair of DNA in chromatin.
Energy Flows in Graphene: Hot Carrier Dynamics and Cooling
Creators: name: Song, Justin C. W.
name: Levitov, Leonid S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Long lifetimes of hot carriers can lead to qualitatively new types of responses in materials. The magnitude and time scales for these responses reflect the mechanisms governing energy flows. We examine the microscopics of two processes which are key for energy transport, focusing on the unusual behavior arising due to graphene's unique combination of material properties. One is hot carrier generation in its photoexcitation dynamics, where hot carriers multiply through an Auger type carrier-carrier scattering cascade. The hot-carrier generation manifests itself through elevated electronic temperatures which can be accessed in a variety of ways, in particular optical conductivity measurements. Another process of high interest is electron-lattice cooling. We survey different cooling pathways and discuss the cooling bottleneck arising for the momentum-conserving electron-phonon scattering pathway. We show how this bottleneck can be relieved by higher-order collisions - supercollisions - and examine the variety of supercollision processes that can occur in graphene.
description: 16 pgs, 5 fgs, 1 tbl
Transient Radio Lines from Axion Miniclusters and Axion Stars
Creators: name: Witte, Samuel J.
name: Baum, Sebastian
name: Lawson, Matthew
name: Marsh, M. C. David
name: Millar, Alexander J.
name: Salinas, Gustavo
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Gravitationally bound clumps of dark matter axions in the form of 'miniclusters' or even denser 'axion stars' can generate strong radio signals through axion-photon conversion when encountering highly magnetised neutron star magnetospheres. We systematically study encounters of axion clumps with neutron stars and characterise the axion infall, conversion and the subsequent propagation of the photons. We show that the high density and low escape velocity of the axion clumps lead to strong, narrow, and temporally characteristic transient radio lines with an expected duration varying from seconds to months. Our work comprises the first end-to-end modeling pipeline capable of characterizing the radio signal generated during these transient encounters, quantifying the typical brightness, anisotropy, spectral width, and temporal evolution of the radio flux. The methods developed here may prove essential in developing dedicated radio searches for transient radio lines arising from miniclusters and axion stars.
description: v2: Minor updates made to match published version. v1: 17 pages, 15 figures
Chaos in Jahn-Teller Rattling
Creators: name: Hotta, Takashi
name: Shudo, Akira
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We unveil chaotic behavior hidden in the energy spectrum of a Jahn-Teller ion vibrating in a cubic anharmonic potential as a typical model for rattling in cage-structure materials. When we evaluate the nearest-neighbor level-spacing distribution $P(s)$ of eigenenergies of the present oscillator system, we observe the transition of $P(s)$ from the Poisson to the Wigner distribution with the increase of cubic anharmonicity, showing the occurrence of chaos in the anharmonic Jahn-Teller vibration. The energy scale of the chaotic region is specified from the analysis of $P(s)$ and we discuss a possible way to observe chaotic behavior in the experiment of specific heat. It is an intriguing possibility that chaos in nonlinear physics could be detected by a standard experiment in condensed matter physics.
description: 5 pages, 4 figures
Functionalizing Aromatic Compounds with Optical Cycling Centers
Creators: name: Zhu, Guo-Zhu
name: Mitra, Debayan
name: Augenbraun, Benjamin L.
name: Dickerson, Claire E.
name: Frim, Michael J.
name: Lao, Guanming
name: Lasner, Zack D.
name: Alexandrova, Anastassia N.
name: Campbell, Wesley C.
name: Caram, Justin R.
name: Doyle, John M.
name: Hudson, Eric R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Molecular design principles provide guidelines for augmenting a molecule with a smaller group of atoms to realize a desired property or function. We demonstrate that these concepts can be used to create an optical cycling center that can be attached to a number of aromatic ligands, allowing the scattering of many photons from the resulting molecules without changing the molecular vibrational states. We provide further design principles that indicate the ability to expand this work. This represents a significant step towards a quantum functional group, which may serve as a generic qubit moiety that can be attached to a wide range of molecular structures and surfaces.
description: 6 pages, 3 figures
DNA Interstrand Cross-Links Induce Futile Repair Synthesis in Mammalian Cell Extracts
Creators: name: Hearst, J. E.
name: Chen, D. J.
name: Harris, T. M.
name: Bessho, T.
name: Sancar, A.
name: Mu, D.
name: Nechev, L. V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2000

description: DNA interstrand cross-links are induced by many carcinogens and anticancer drugs. It was previously shown that mammalian DNA excision repair nuclease makes dual incisions 5′ to the cross-linked base of a psoralen cross-link, generating a gap of 22 to 28 nucleotides adjacent to the cross-link. We wished to find the fates of the gap and the cross-link in this complex structure under conditions conducive to repair synthesis, using cell extracts from wild-type and cross-linker-sensitive mutant cell lines. We found that the extracts from both types of strains filled in the gap but were severely defective in ligating the resulting nick and incapable of removing the cross-link. The net result was a futile damage-induced DNA synthesis which converted a gap into a nick without removing the damage. In addition, in this study, we showed that the structure-specific endonuclease, the XPF-ERCC1 heterodimer, acted as a 3′-to-5′ exonuclease on cross-linked DNA in the presence of RPA. Collectively, these observations shed some light on the cellular processing of DNA cross-links and reveal that cross-links induce a futile DNA synthesis cycle that may constitute a signal for specific cellular responses to cross-linked DNA.
Focus Group Discussion Report Final
Creators: name: Chemeda, Beshea
Publisher: name: figshare
Year: 2022
Subjects: subject: Climate Science
subject: 50205 Environmental Management
subject: FOS: Earth and related environmental sciences
subject: Environmental Science

description: This document is the report of focus group discussions held in Gimbi district, western Ethiopia. It was trancsribed to be included in the manuscript prepared for publication. The manuscript title is " Determinants on perception of climate change and adaptation strategies of coffee-based agroforestry farmers in western Ethiopia". 
On Gradient like Properties of Population games, Learning models and Self Reinforced Processes
Creators: name: Benaim, Michel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Dynamical Systems (math.DS)
subject: Probability (math.PR)
subject: FOS: Mathematics

description: We consider ordinary differential equations on the unit simplex of $\RR^n$ that naturally occur in population games, models of learning and self reinforced random processes. Generalizing and relying on an idea introduced in \cite{DF11}, we provide conditions ensuring that these dynamics are gradient like and satisfy a suitable "angle condition". This is used to prove that omega limit sets and chain transitive sets (under certain smoothness assumptions) consist of equilibria; and that, in the real analytic case, every trajectory converges toward an equilibrium. In the reversible case, the dynamics are shown to be $C^1$ close to a gradient vector field. Properties of equilibria -with a special emphasis on potential games - and structural stability questions are also considered.
Exact Diagonalization of Heisenberg SU(N) models
Creators: name: Nataf, Pierre
name: Mila, Frederic
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: Building on advanced results on permutations, we show that it is possible to construct, for each irreducible representation of SU(N), an orthonormal basis labelled by the set of {\it standard Young tableaux} in which the matrix of the Heisenberg SU(N) model (the quantum permutation of N-color objects) takes an explicit and extremely simple form. Since the relative dimension of the full Hilbert space to that of the singlet space on $n$ sites increases very fast with N, this formulation allows to extend exact diagonalizations of finite clusters to much larger values of N than accessible so far. Using this method, we show that, on the square lattice, there is long-range color order for SU(5), spontaneous dimerization for SU(8), and evidence in favor of a quantum liquid for SU(10).
description: To be published in Physical Review Letters