cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: An Interdisciplinary Examination of the Interpretation and Delivery of Social Inclusion in the Arts
Creators: name: Catherine Durrer, Victoria
Publisher: name: University of Liverpool Repository
Year: 2023

description: Britain's current Labour government has tied the arts to its broader agenda of promoting social inclusion (DCMS 1998; OCMS 2000). This thesis takes this policy shift as a starting point and critically interprets the nature of the collective and individual understandings of culture it makes evident. Informed by the work of Arnold (2003 [1867-69]) and Williams (1958), it considers how such apparently contradictory schools of thought are implied not only in Labour's cultural policy for inclusion, but also in its delivery within the arts, a field perceived to have its own inherent issues of exclusivity and inclusivity (Bourdieu and Oarbel 1991). Employing methodologies from art history and the social sciences, the thesis takes an interdisciplinary approach to contextualise the development and practice of the social inclusion agenda within the arts (Silver 1998; Hooper-Greenhill 2000a; Bevir and Rhodes 2003). In this way, the research aims to add two key areas of consideration to the debate on social inclusion and the arts: the community or the 'field' of the arts and the individual practices within that field (Bourdieu 2000). The thesis looks at case study projects in three art galleries in Liverpool: the Bluecoat, Tate Liverpool, and the Walker Art Gallery. By contextualising the historical developments of each organisation, the thesis examines how each gallery, its staff and its local public may be interpreting the policy of social inclusion in 'real' terms (Bevir and Rhodes 2(03). Through semi-structured interviews with both practitioners and participants involved in the interpretation and subsequent delivery of policy and through the participant observation of particular projects, this research examines the interpretation of social inclusion within practice. The provision of access to art galleries for individuals labeled 'socially excluded' is not necessarily deemed vital to practitioners or even all participants; rather it is provision of access for individuals who may not feel comfortable in an arts setting. The perception of art's exclusivity is seen to change via the different capacities in which both the arts organisations and the individuals working within them may allow perceived boundaries of exclusion to be negotiated. Opposed views on the value of culture are actually conjoined to promote forms of inclusion that are mediated and shaped by 'interpretive communities' (Hooper-Greenhill 2000a). By highlighting the negotiated nature of exclusion as a process of learning (Wenger 1998), this study aims to contribute to the construction of a more reflective practice in the arena of social inclusion and the arts.
Diabetic retinopathy in the SEARCH for Diabetes in Youth Cohort: a pilot study: Retinopathy in youth with diabetes
Creators: name: Lawrence, J. M.
name: Davis, C.
name: Klein, B. E.
name: Saadine, J.
name: Klein, R.
name: D’Agostino, R. B.
name: Dabelea, D.
name: Rodriguez, B. L.
name: Pihoker, C.
name: Dolan, L.
name: Garg, S.
name: Mayer-Davis, E. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The aim of this pilot study was to generate an initial estimate of the prevalence and correlates of diabetic retinopathy in a racially and ethnically diverse sample of youth with Type 1 and Type 2 diabetes mellitus.
Dilations, Linear Matrix Inequalities, the Matrix Cube Problem and Beta Distributions
Creators: name: Helton, J. William
name: Klep, Igor
name: McCullough, Scott A.
name: Schweighofer, Markus
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: Optimization and Control (math.OC)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 47A20, 46L07, 13J30 (Primary), 60E05, 33B15, 90C22 (Secondary)

description: An operator C on a Hilbert space H dilates to an operator T on a Hilbert space K if there is an isometry V from H to K such that C=V^*TV. A main result of this paper is, for a positive integer d, the simultaneous dilation, up to a sharp factor $\vartheta(d)$, of all d-by-d symmetric matrices of operator norm at most one to a collection of commuting self-adjoint contraction operators on a Hilbert space. An analytic formula for $\vartheta(d)$ is derived, which as a by-product gives new probabilistic results for the binomial and beta distributions. Dilating to commuting operators has consequences for the theory of linear matrix inequalities (LMIs). Given a tuple A=(A_1,...,A_g) of symmetric matrices of the same size, L(x):=I-\sum A_j x_j is a monic linear pencil. The solution set S_L of the corresponding linear matrix inequality, consisting of those x in R^g for which L(x) is positive semidefinite (PsD), is a spectrahedron. The set D_L of tuples X=(X_1,...,X_g) of symmetric matrices (of the same size) for which L(X):=I-\sum A_j \otimes X_j is PsD, is a free spectrahedron. A result here is: any tuple X of d-by-d symmetric matrices in a bounded free spectrahedron D_L dilates, up to a scale factor, to a tuple T of commuting self-adjoint operators with joint spectrum in the corresponding spectrahedron S_L. From another viewpoint, the scale factor measures the extent that a positive map can fail to be completely positive. Given another monic linear pencil M, the inclusion D_L \subset D_M obviously implies the inclusion S_L \subset S_M and thus can be thought of as its free relaxation. Determining if one free spectrahedron contains another can be done by solving an explicit LMI and is thus computationally tractable. The scale factor for commutative dilation of D_L gives a precise measure of the worst case error inherent in the free relaxation, over all monic linear pencils M of size d.
description: v4: 93 pages including a table of contents and index, added paragraph at the end of the introduction, several minor changes; v3: 90 pages, new section on including balls into spectrahedra, changes to the introduction; v2: title change, introduction rewritten; v1: 77 pages including a table of contents
A pedagogical approach to creative copying from photographic imagery: A drawing-led practice-based research inquiry
Creators: name: Parker, Mark
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Full paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
A Case Study of Collaborative Practice: Working to promote cross-curricular thinking and making within schools
Creators: name: Wadkin, Gareth
name: Pratt, Caroline
Publisher: name: FUTURESCAN
Year: 2019
Subjects: subject: 120306 Textile and Fashion Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Short paper presented at the Association of Fashion & Textile Courses (FTC) conference Futurescan 4: Valuing Practice, University of Bolton, UK, 23rd-24th January 2019.
Futurescan 4: Valuing PracticeEdited by: Helena Britt, Kevin Almond, Laura MorganISBN: 978-1-5272-4969-1
Ageing, later life and caring in the LGBTQIA+ community
Creators: name: Odunewu, Chrispina
name: O'Connor, Gráinne
Publisher: name: The Open University
Year: 2023
Subjects: classificationCode: 420301
subject: Aged health care
classificationCode: 420303
subject: Family care
classificationCode: 420304
subject: General practice
classificationCode: 420305
subject: Health and community services
classificationCode: 420308
subject: Health informatics and information systems
classificationCode: 420309
subject: Health management
classificationCode: 420315
subject: One health
classificationCode: 420318
subject: People with disability
classificationCode: 420319
subject: Primary health care
classificationCode: 420399
subject: Health services and systems not elsewhere classified

description: Accessible document to accompany Ageing Well Public Talk Series 22/23. Talk 11: Ageing, later life and caring in LGBTQ communities - Joe DeLappe & Tony Collins-Moore July 12th 2023
 The LGBTQ+ community is ageing like other communities but are there different issues? In this talk Joe and Tony will explore what is the appropriate way to support the LGBTQ+ community to age well and how caring can work from an alternative family dynamic perspective.
 Tony Collins-Moore - Carers Wellbeing Academy Manager, Carers Centre Tower Hamlets. Tony describes himself as advocate or & safeguarding champion, husband, animal lover, honest, fun & life loving man. Dr Joseph DeLappe – Research Associate, Faculty of Wellbeing, Education & Language Studies, The Open University. Joe works on a range of health, wellbeing, and social care projects at the OU. His own research interests include health inequalities for LGBTQ+ populations, particularly as they age.
title: Search for non-prompt photons in a diphoton and large missing transverse momentum final state at the ATLAS Detector
Creators: name: Lehan, Allan
Publisher: name: University of Liverpool Repository
Year: 2015

description: A search for non-prompt photons in diphoton events with large missing transverse energy at the ATLAS detector is presented in this thesis. This search was performed using data collected from proton-proton collisions provided by the Large Hadron Collider at CERN at two energies: 4.8 fb^-1 collected at a center of mass energy of 7 TeV in 2011 and 20.3 fb^-1 collected at a center of mass energy of 8 TeV in 2012. The theoretical motivation for this search lies in the Gauge Mediated Symmetry Breaking models in which the lightest neutralino can be long-lived and decay to a photon and a gravitino, which is stable and the source of missing transverse momentum in these models. The photons produced in these decays have two unique properties due to the finite lifetime of the neutralino: they will not point back to the primary collision vertex and they will arrive at the electromagnetic calorimeter delayed compared to promptly produced photons. These two signatures were used to search for non-prompt photons in a simplified model in which the only two free parameters are the lifetime of the neutralino and the effective supersymmetry breaking scale, corresponding to the mass of the neutralino. In the two datasets, no significant excess over the Standard Model predictions was observed. These results were used to set exclusion limits on the lifetime and mass of the lightest neutralinos at the 95% confidence level: neutralinos with lifetimes varying from 250 ps to 50 ns in the mass range of 95 GeV to 240 GeV were excluded by the 7 TeV analysis, neutralinos with lifetimes varying from 250 ps to 100 ns in the mass range of 120 GeV to 440 GeV were excluded by the 8 TeV analysis.
Masterclasses on Open Science
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: To fulfil the gaps in training and education on Open Science skills, RI4C2 has created Masterclasses on Open Science, a collection of Open Educational Resources featuring five instructional videos and two podcasts with internationally renowned Open Science experts sharing their insights and best practices on how to approach some Open Science practices not yet widely established.
Operads from posets and Koszul duality
Creators: name: Giraudo, Samuele
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 05E99, 05C05, 06A11, 18D50

description: We introduce a functor ${\sf As}$ from the category of posets to the category of nonsymmetric binary and quadratic operads, establishing a new connection between these two categories. Each operad obtained by the construction ${\sf As}$ provides a generalization of the associative operad because all of its generating operations are associative. This construction has a very singular property: the operads obtained from ${\sf As}$ are almost never basic. Besides, the properties of the obtained operads, such as Koszulity, basicity, associative elements, realization, and dimensions, depend on combinatorial properties of the starting posets. Among others, we show that the property of being a forest for the Hasse diagram of the starting poset implies that the obtained operad is Koszul. Moreover, we show that the construction ${\sf As}$ restricted to a certain family of posets with Hasse diagrams satisfying some combinatorial properties is closed under Koszul duality.
description: 40 pages
Scalar correlators near the 3-flavor thermal critical point
Creators: name: Jin, Xiao-Yong
name: Kuramashi, Yoshinobu
name: Nakamura, Yoshifumi
name: Takeda, Shinji
name: Ukawa, Akira
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We investigate screening masses at both sides of the first order finite temperature transition with 3 quark flavors using the nonperturbatively improved clover fermion action and the Iwasaki gauge action. We have developed the method of hierarchical truncations with stochastic probing to accelerate the noise estimator for evaluating quark loops at every spatial lattice slices. At parameter values we study, the flavor singlet scalar meson has a screening mass about half of the pion screening mass. It becomes lighter as the system approaches the critical endpoint.
description: 7 pages, 4 figures, and 3 tables, presented at the 32nd International Symposium on Lattice Field Theory (LATTICE2014), 23-28 June, 2014, Columbia University New York, NY
Probing GPDs in Ultraperipheral Collisions
Creators: name: Ivanov, D. Yu.
name: Pire, B.
name: Szymanowski, L.
name: Wagner, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Ultraperipheral collisions in hadron colliders give new opportunites to investigate the hadron stucture through exclusive photoproduction processes. We describe the possibility of measuring the Generalized Parton Distributions in the Timelike Compton Scattering process and in the production of heavy vector meson.
description: to appear in Proceedings Diffraction 2014, Primosten, Croatia, sept 10-16, 2014
title: A thematic analysis of Spanish word order : theoretical and pedagogical aspects
Creators: name: Berrocoso, Solbella
Publisher: name: University of Liverpool Repository
Year: 2023

description: Word order variations in Spanish have led scholars to consider it as a language with flexible word order in comparison with languages such as French or English. Attention has been mainly centred on syntactic variations involving the placement of the subject. Today, the widespread assumption is that Spanish is a pragmatically motivated language; consequently, studies have started to focus on real occurring data in order to study the pragmatic factors that intervene in the creation of meaning. The fact that the pragmatic factors are independent of position makes it difficult to use them as indicators to explain word order variations. Further, studying language in context implies that it more complex to single out a specific feature, because every element of the system collaborates in the creation of meaning.
title: Vertex unique labelled subgraph mining
Creators: name: Yu, Wen
Publisher: name: University of Liverpool Repository
Year: 2016

description: This thesis proposes the novel concept of Vertex Unique Labelled Subgraph (VULS) mining with respect to the field of graph-based knowledge discovery (or graph mining). The objective of the research is to investigate the benefits that the concept of VULS can offer in the context of vertex classification. A VULS is a subgraph with a particular structure and edge labelling that has a unique vertex labelling associated with it within a given (set of) host graph(s). VULS can describe highly discriminative and significant local geometries each with a particular associated vertex label pattern. This knowledge can then be used to predict vertex labels in ``unseen" graphs (graphs with edge labels, but without vertex labels). Thus this research is directed at identifying (mining) VULS, of various forms, that ``best" serve to both capture effectively graph information, while at the same time allowing for the generation of effective vertex label predictors (classifiers). To this end, four VULS classifiers are proposed, directed at mining four different kinds of VULS: (i) complete, (ii) minimal, (iii) frequent and (iv) minimal frequent. The thesis describes and discusses each of these in detail including, in each case, the theoretical definition and algorithms with respect to VULS identification and prediction. A full evaluation of each of the VULS categories is also presented. VULS has wide applicability in areas where the domain of interest can be represented in the form of some sort of a graph. The evaluation was primarily directed at predicting a form of deformation, known as springback, that occurs in the Asymmetric Incremental Sheet Forming (AISF) manufacturing process. For the evaluation two flat-topped, square-based, pyramid shapes were used. Each pyramid had been manufactured twice using Steel and twice using Titanium. The utilisation of VULS was also explored by applying the VULS concept to the field of satellite image interpretation. Satellite data describing two villages located in a rural part of the Ethiopian hinterland were used for this purpose. In each case the ground surface was represented in a similar manner to the way that AISF sheet metal surfaces were represented, with the $z$ dimension describing the grey scale value. The idea here was to predict vertex labels describing ground type. As will become apparent, from the work presented in this thesis, the VULS concept is well suited to the task of 3D surface classification with respect to AISF and satellite imagery. The thesis demonstrates that the use of frequent VULS (rather than the other forms of VULS considered) produces more efficient results in the AISF sheet metal forming application domain, whilst the use of minimal VULS provided promising results in the context of the satellite image interpretation domain. The reported evaluation also indicates that a sound foundation has been established for future work on more general VULS based vertex classification.
Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects
Creators: name: Mohlke, K. L.
name: Valle, T. T.
name: Bergman, R. N.
name: Watanabe, R. M.
name: Buchanan, T. A.
name: Silander, K.
name: Tuomilehto, J.
name: Collins, F. S.
name: Boehnke, M.
name: Lazaridis, K. N.
name: Scott, L. J.
name: Conneely, K. N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Resistin is a peptide hormone produced by adipocytes that is present at high levels in sera of obese mice and may be involved in glucose homeostasis through regulation of insulin sensitivity. Several studies in humans have found associations between polymorphisms in the resistin gene and obesity, insulin sensitivity and blood pressure. An association between variation in the resistin gene and Type 2 diabetes has been reported in some, but not all studies. The aim of this study was to analyse variants of the resistin gene for association with Type 2 diabetes and related traits in a Finnish sample.
Ageing, later life and caring in the LGBTQIA+ community
Creators: name: Odunewu, Chrispina
Publisher: name: The Open University
Year: 2023
Subjects: classificationCode: 420301
subject: Aged health care
classificationCode: 420303
subject: Family care
classificationCode: 420304
subject: General practice
classificationCode: 420305
subject: Health and community services
classificationCode: 420308
subject: Health informatics and information systems
classificationCode: 420309
subject: Health management
classificationCode: 420315
subject: One health
classificationCode: 420318
subject: People with disability
classificationCode: 420319
subject: Primary health care
classificationCode: 420399
subject: Health services and systems not elsewhere classified

description: Accessible document to accompany Ageing Well Public Talk Series 22/23. Talk 11: Ageing, later life and caring in LGBTQ communities - Joe DeLappe & Tony Collins-Moore July 12th 2023
 The LGBTQ+ community is ageing like other communities but are there different issues? In this talk Joe and Tony will explore what is the appropriate way to support the LGBTQ+ community to age well and how caring can work from an alternative family dynamic perspective.
 Tony Collins-Moore - Carers Wellbeing Academy Manager, Carers Centre Tower Hamlets. Tony describes himself as advocate or & safeguarding champion, husband, animal lover, honest, fun & life loving man. Dr Joseph DeLappe – Research Associate, Faculty of Wellbeing, Education & Language Studies, The Open University. Joe works on a range of health, wellbeing, and social care projects at the OU. His own research interests include health inequalities for LGBTQ+ populations, particularly as they age.
Errata Corrige - Abstracts have not been included in the 55th SItI National Congress
Creators: name: Lai, Piero Luigi
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: errata corrige
err

description: Errata Corrige - Abstracts have not been included in the 55th SItI National Congress
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations (Diabetologia DOI: 10.1007/s00125-007-0887-6)
Creators: name: Rolandsson, O.
name: Fawcett, K. A.
name: Franks, P. W.
name: Mohlke, K. L.
name: Barroso, I.
name: Wareham, N. J.
name: Payne, F.
name: Olsson, T.
name: Sandhu, M. S.
name: Willer, C.
name: Hallmans, G.
name: Dina, C.
name: Debenham, S. L.
name: Froguel, P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Mutations at the Wolframin encoding gene, WFS1, cause Wolfram syndrome, a rare neurological condition. Associations between single nucleotide polymorphisms (SNPs) at WFS1 and type 2 diabetes have recently been reported. In the present study, we sought to replicate those associations in a northern Swedish case-control study for type 2 diabetes. We also meta-analyzed published and previously unpublished data from Sweden, Finland and France to obtain updated summary effect estimates.
Open Science practices: Case synthesis
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: This report presents the main findings from the RI4C2 project's exploration into Open Science practices currently being implemented at European universities. To identify and discuss established and emerging Open Science practices, case descriptions about carried out practices were gathered from researchers and members of the administrative staff at the seven member universities of European Campus of City-Universities Alliance (EC2U).
title: An in situ study to determine the effects of casein phosphopeptide-amorphous calcium phosphate toothpaste in orthodontic patients
Creators: name: Garry, Andrew
Publisher: name: University of Liverpool Repository
Year: 2016

description: Objectives: To investigate the remineralisation of enamel subsurface lesions with CPP-ACP toothpaste compared with regular fluoride toothpaste in orthodontic patients. Design: Randomised controlled clinical trial with a cross-over design. Setting: Orthodontic department at the Liverpool University Dental Hospital. Participants: 12 orthodontic patients receiving fixed orthodontic treatment. Methods: Demineralised sub-surface enamel lesions were placed in situ onto a fixed appliance in the lower premolar region. Participants were randomly allocated to receive either standard fluoride toothpaste or a CPP-ACP paste (GC Tooth Mousse™) in addition to the fluoride toothpaste. Transverse Microradiography (TMR) was used to analyse and compare the mineral content profiles of the lesions. Results: Mineral loss ΔZ reduced by 15.4% and 24.6% for the fluoride and CPP-ACP groups respectively, with a statistical significant difference between these groups (p = 0.023). Lesion depth reduced by 1.6% and 11.1% for fluoride and CPP-ACP groups respectively, with a statistically significant difference between these groups (p = 0.037). Lesion width reduced by 4.5% and 15.3% for fluoride and CPP-ACP groups respectively, with a statistically significant difference between these groups (p=0.015). Conclusion/Implications: Remineralisation occurred during the in situ phase regardless of treatment group allocation, however the CPP-ACP combined with fluoride group demonstrated a statistically significant increased remineralising effect. CPP-ACP paste may be beneficial for patients undergoing orthodontic treatment who are at high risk of demineralisation or who have demonstrated early signs of white spot lesion formation. Trial Registration: Registered on Current Control Trials http://www.controlled-trials.com/ISRCTN04899524
title: Integration of a maternal psychosocial well-being component into a early child-development intervention
Creators: name: Zafar, Shamsa
Publisher: name: University of Liverpool Repository
Year: 2015

description: Maternal psychosocial well-being (MPW) is a comprehensive concept that covers the psychological (e.g., depression, distress, anxiety, coping, mental health,) and social (e.g., family and community support, empowerment, relationships, culture) aspects of motherhood. High rates of poor maternal mental health, with maternal depression the most prevalent condition, have been reported in the low and middle income countries, including Pakistan. Though evidence based interventions exist to address maternal depression, these have not been translated into policy because of various implementation barriers. Integration of these interventions into existing maternal and child health (MCH) programmes has been suggested as a strategy to provide accessible care to mothers. In the current study we developed and integrated a cognitive behavioural therapy–based MPW intervention (the 5 pillars approach) into a child nutrition and development program. Following qualitative research with community health workers (CHWs) and families, CHWs were trained in (1) empathic listening, (2) family engagement, (3) guided discovery using pictures, (4) behavioural activation, and (5) problem solving. A qualitative feasibility study in one area demonstrated that CHWs were able to apply these skills effectively to their work, and the approach was found to be useful by CHWs and mothers. This work provides vital information on the lessons learnt in the implementation of a maternal psychosocial wellbeing intervention for universal use. The facilitating factors included mothers being the central focus of the intervention, utilizing existing local CHWs whom the mothers trust, simple training and regular supervision, and an approach that facilitates, and does not add, to the CHWs’ work.
Case descriptions on Open Science
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: This report aims at identifying and establishing the best practices for the practical implementation of a range of Open Science practices, such as data sharing and FAIR data management, open access publishing, open code, open engagement of societal actors, open evaluation, participatory science and preregistration. It supports universities in developing a broader and a more practical perspective towards supporting researchers in meeting the requirements of Open Science.
title: A proteomic and biochemical approach to understanding the mode of action of a novel class insecticide
Creators: name: Powell, Gerard
Publisher: name: University of Liverpool Repository
Year: 2023

description: In order to control insect populations that are resistant to the currently used insecticides, new compounds with completely different modes of action need to be developed. One such novel insecticide is Pyridalyl; it shows high specificity towards lepidopteran pests, no phytotoxicity and it is capable of controlling lepidopteran populations that are resistant to the currently used insecticides. The main aim of this project was to elucidate the mode of action of Pyridalyl using biochemical and proteomic techniques.
Genetic variant selection: learning across traits and sites
Creators: name: Stell, Laurel
name: Sabatti, Chiara
Publisher: name: arXiv
Year: 2015
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: We consider resequencing studies of associated loci and the problem of prioritizing sequence variants for functional follow-up. Working within the multivariate linear regression framework helps us to account for correlation across variants, and adopting a Bayesian approach naturally leads to posterior probabilities that incorporate all information about the variants' function. We describe two novel prior distributions that facilitate learning the role of each variant by borrowing evidence across phenotypes and across mutations in the same gene. We illustrate their potential advantages with simulations and re-analyzing a dataset of sequencing variants.
description: Published at http://www.genetics.org/content/202/2/439 in GENETICS (http://www.genetics.org)
title: Alcohol treatment in the National Health Service : challenging the paradigm
Creators: name: Cobain, Kathryn
Publisher: name: University of Liverpool Repository
Year: 2023

description: Between 3 and 6% of the population in England are dependent on alcohol. However, only 5.6% access treatment per annum. A significant proportion of patients presenting with alcohol dependence do so via a GP or hospital emergency aepariment (ED). It is therefore important to consider presentation within these settings as an opportunity for alcohol specific treatment.
TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study
Creators: name: Pankow, J. S.
name: Bielinski, S. J.
name: Folsom, A. R.
name: North, K. E.
name: Boerwinkle, E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: We hypothesize that transcription factor 7-like 2 (TCF7L2) single nucleotide polymorphisms (SNPs) are associated with cardiovascular disease (CVD) and that the associations differ in diabetic and non-diabetic participants.
A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis
Creators: name: Wright, F. A.
name: Blackman, S. M.
name: Cutting, G. R.
name: Naughton, K. M.
name: Knowles, M. R.
name: Hsu, S.
name: Drumm, M. L.
name: Ritter, S. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Insulin-requiring diabetes affects 25–50% of young adults with cystic fibrosis (CF). Although the cause of diabetes in CF is unknown, recent heritability studies in CF twins and siblings indicate that genetic modifiers play a substantial role. We sought to assess whether genes conferring risk for diabetes in the general population may play a risk modifying role in CF.
Directional learning and the provisioning of public goods
Creators: name: Nax, Heinrich H.
name: Perc, Matjaz
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Computer Science and Game Theory (cs.GT)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: We consider an environment where players are involved in a public goods game and must decide repeatedly whether to make an individual contribution or not. However, players lack strategically relevant information about the game and about the other players in the population. The resulting behavior of players is completely uncoupled from such information, and the individual strategy adjustment dynamics are driven only by reinforcement feedbacks from each player's own past. We show that the resulting "directional learning" is sufficient to explain cooperative deviations away from the Nash equilibrium. We introduce the concept of k-strong equilibria, which nest both the Nash equilibrium and the Aumann-strong equilibrium as two special cases, and we show that, together with the parameters of the learning model, the maximal k-strength of equilibrium determines the stationary distribution. The provisioning of public goods can be secured even under adverse conditions, as long as players are sufficiently responsive to the changes in their own payoffs and adjust their actions accordingly. Substantial levels of public cooperation can thus be explained without arguments involving selflessness or social preferences, solely on the basis of uncoordinated directional (mis)learning.
description: 7 two-column pages, 3 figures; accepted for publication in Scientific Reports
The challenges of urban family physician program over the past decade in Iran: a scoping review and qualitative study with policy-makers
Creators: name: Shahabi, Saeed
name: Bagheri Lankarani, Kamran
name: Honarvar, Behnam
name: Zarei, Fatemeh
name: Behzadifar, Masoud
name: Hedayati, Maryam
name: Fardid, Mojgan
name: Rafiei, Fatemeh
name: Martini, Mariano
name: Rafiei Nejad, Soheila
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Family Physician, scoping review, qualitative study, Iran
Family Physician Program
health policy

description: Introduction: Despite all the advantages of urban family physician program (UFPP), there is still a gap between UFPP and what is actually achieved by the community after its implementation in Iran. In response, this study attempted to review published studies related to the barriers to the implementation of the UFPP in Iran as well as potential solutions to improve it. Further, a qualitative study was conducted to learn the perspectives of experts at the national level and in the Fars province in order to better understand the program's challenges. Methods: This study was conducted in two phases. First, a scoping review was done, aiming to identify the common barriers and potential solutions to implementing UFPP in Iran. Second, a qualitative study using semi-structured interviews was conducted to investigate the views of decision- and policy-makers regarding barriers to and solutions for implementing the UFPP in the Fars province over the last decade. The findings were classified using the five control knobs framework (Organization, financing, payment, regulation, and behavior). Results: The most common barriers to UFPP were: 1) organization (ununited stewardship function of the Ministry of Health, weak management and planning, inadequate training of human resources, and a weak referral system); 2) financing (fragmented insurance funds, insufficient financial resources, and instability of financial resources); 3) payment (inappropriate payment mechanisms and delay in payments); 4) regulation (cumbersome laws and unclear laws); and 5) behavior (cultural problems and conflict of interests). On the other hand, several solutions were identified to improve the implementation of UFPP, including: enhancing the role of government; improving the referral system; providing comprehensive training for UFPP providers; considering sustainable financial resources; moving towards mixed-payment mechanisms; employing appropriate legal and regulatory frameworks; enhancing community awareness; and elevating incentive mechanisms. Conclusion: Our research found that, despite the UFPP having been in place for a decade in Iran, there are still significant challenges in all five components. Therefore, the promotion of this program requires solving the existing implementation challenges in order to achieve the predetermined goals. The ideas in this study can be used to improve the current program in Fars Province and bring it to other cities in Iran.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
On a Phi-Kirchhoff multivalued problem with critical growth in an Orlicz-Sobolev space
Creators: name: Figueiredo, Giovany M.
name: Santos, Jefferson A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: This paper is concerned with the multiplicity of nontrivial solutions in an Orlicz-Sobolev space for a nonlocal problem with critical growth, involving N-functions and theory of locally Lispchitz continuous functionals.
title: Young women's narratives of violence
Creators: name: Morley, Sharon
Publisher: name: University of Liverpool Repository
Year: 2023

description: There is a growing interest in females who commit acts of violence with the mass media claiming that we are witnessing the emergence of a breed of new violent females. This thesis, however, challenges the argument that we are seeing the emergence of sassy, independent, violent females who are imitating, or in some circumstances being more violent, than males. Based on narrative interviews with a group of young women in the North West of England, this thesis reveals the pervasive nature of social control mechanisms that are at play in these young women's lives. In order to adhere to entrenched ideas of appropriate female behaviour, these young women employ a variety of preventative strategies in order to avoid or negotiate violence, sexual or otherwise. As such these strategies were not only employed to prevent violence by males, but also to prevent violence from other women, thus demonstrating women's universal fear of men and their particular fear ofother women. This thesis also builds on Kelly's (1988) continuum of violence theory, suggesting that a matrix of violence is better able to capture the subtleties and complexities ofviolence in the everyday lives ofthese young women. As such, there is no clear-cut distinction between victims and perpetrators, thus disrupting the dichotomy in which women are seen either as innocent victims or as offenders. Rather, the young women may fmd themselves at various places in this matrix as the dynamics of a conflict change. These conflicts are not only evident with regard to physical violence but also with the young women either being victims, or perpetrators of, what was termed 'mean' or 'bitchy' behaviour. However, the author suggests that we should be careful not to conflate the severity of this 'mean' behaviour with the harm inflicted by physical violence. The young women's motivations for using violence are also explored. Important here is the concept of 'respect', which, it is argued is not gender specific. Rather the young women regarded respect in the same marmer as boys and men; it gave them status among their peers. However, it was found that ideas of respectability and respectable femininity were gender specific. It was also evident that these latter terms carried different meanings for the young women at various times in their lives depending upon the circumstances and situations they found themselves in.
Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets
Creators: name: Dai, C.
name: Whitfield, T. T.
name: Wasserman, D. H.
name: Powers, A. C.
name: Kim, H. S.
name: Brissova, M.
name: Luther, J. M.
name: Kreger, M. T.
name: Luo, P.
name: Brown, N. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Aldosterone concentrations increase in obesity and predict the onset of diabetes. We investigated the effects of aldosterone on glucose homeostasis and insulin secretion in vivo and in vitro.
Ethics and humanization of care: Reflections in the teaching of French institutional psychotherapy experience
Creators: name: Schiavone, Valeria
name: Alfano, Linda
name: Ciliberti, Rosagemma
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: Institutional psychotherapy
therapeutic process
role-based interaction
rehabilitation
dignity
individuality
Bioetics

description: French institutional psychotherapy, developed by Jean Oury and his team at the Clinic de la Borde, has played a significant role in the evolution of psychotherapeutic practice, highlighting the importance of considering the institutional context as a determining factor in understanding and treating mental disorders. This innovative approach, based on recognition of asylums' pathogenic effects, has placed particular emphasis on the humanisation of treatment and the application of bioethical principles within psychiatric institutions. This article aims to investigate the key elements of French institutional psychotherapy, analysing its relationship with bioethics and its contribution to the humanisation of care.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
First Citizen Science projects
Creators: name: RI4C2 project
Publisher: name: Zenodo
Year: 2024

description: This report showcases the Citizen Science projects that have been submitted to various European and national call for projects. These projects represent pioneering efforts in harnessing public engagement to advance scientific discovery and problem-solving across different disciplines. By showcasing these initiatives, the report seeks to underscore their significance in advancing Citizen Science through collaborative efforts between researchers, citizens, and institutions.
title: Some contributions to Markov decision processes
Creators: name: Chu, Shanyun
Publisher: name: University of Liverpool Repository
Year: 2016

description: In a nutshell, this thesis studies discrete-time Markov decision processes (MDPs) on Borel Spaces, with possibly unbounded costs, and both expected (discounted) total cost and long-run expected average cost criteria. In Chapter 2, we systematically investigate a constrained absorbing MDP with expected total cost criterion and possibly unbounded (from both above and below) cost functions. We apply the convex analytic approach to derive the optimality and duality results, along with the existence of an optimal finite mixing policy. We also provide mild conditions under which a general constrained MDP model with state-action-dependent discount factors can be equivalently transformed into an absorbing MDP model. Chapter 3 treats a more constrained absorbing MDP, as compared with that in Chapter 2. The dynamic programming approach is applied to a reformulated unconstrained MDP model and the optimality results are obtained. In addition, the correspondence between policies in the original model and the reformulated one is illustrated. In Chapter 4, we attempt to extend the dynamic programming approach for standard MDPs with expected total cost criterion to the case, where the (iterated) coherent risk measure of the cost is taken as the performance measure to be minimized. The cost function under our consideration is allowed to be unbounded from the below, and possibly arbitrarily unbounded from the above. Under a fairly weak version of continuity-compactness conditions, we derive the optimality results for both the finite and infinite horizon cases, and establish value iteration as well as policy iteration algorithms. The standard MDP and the iterated conditional value-at-risk of the cost function are illustrated as two examples. Chapter 5 and 6 tackle MDPs with long-run expected average cost criterion. In Chapter 5, we consider a constrained MDP with possibly unbounded (from both above and below) cost functions. Under Lyapunov-like conditions, we show the sufficiency of stable policies to the concerned constrained problem. Furthermore, we introduce the corresponding space of performance vectors and manage to characterize each of its extreme points with a deterministic stationary policy. Finally, the existence of an optimal finite mixing policy is justified. Chapter 6 concerns an unconstrained MDP with the cost functions unbounded from the below and possibly arbitrarily unbounded from the above. We provide a detailed discussion on the issue of sufficient policies in the denumerable case, establish the average cost optimality inequality (ACOI) and show the existence of an optimal deterministic stationary policy. In Chapter 7, an inventory-production system is taken as an example of real-world applications to illustrate the main results in Chapter 2 and 5.
Smallpox, an ancient term for various infectious diseases: the dreaded Smallpox, the almost unknown Alastrim, the Mpox
Creators: name: Orsini, Davide
name: Martini, Mariano
name: Behzadifar, Masoud
name: Bragazzi, Nicola Luigi
Publisher: name: Journal of Preventive Medicine and Hygiene
Year: 2023
Subjects: History of infectious diseases
epidemiology
ethics
smallpox
Alastrim
epidemics
Mpox
history of infectious diseases
history of Alastrim

description: Introduction: In 2022, the appearance of cases of Mpox outside the countries where the disease is endemic, and of some cases of human-to-human transmission, alerted the scientific community to a virus that is closely related to the smallpox virus. Mpox is a zoonosis and can be transmitted to humans. Following the eradication of smallpox in 1980 and the subsequent cessation of smallpox vaccination, it is emerging as the most important orthopoxvirus in terms of public health impact. Methods: In outlining the current situation of Mpox in the world, the authors frame the virus responsible within a broader reflection on the Orthopoxvirus family, focusing particular attention on the Variola virus, which formerly caused millions of deaths. Discussion: Since Edward Jenner initiated the practice of vaccination, a progressive and careful vaccination campaign has led to the eradication not only of human smallpox but also of a minor form, called Alastrim, which was caused by the same virus. The mode of transmission of Mpox has been debated. At first, it seemed that the disease mainly, though not exclusively, affected men who had sex with other men. This conviction has been partially revised and the WHO recently changed the name of the disease from Monkeypox to Mpox, thereby alleviating the stigma involved. Conclusion: The recent human cases of Mpox have prompted greater surveillance and research into the biology of MPXV and other closely related poxviruses. Studies have focused on the natural history of the virus, its transmission, pathogenesis, host interactions and evolution, and on the development of drugs and vaccines to prevent its spread.
description: Journal of Preventive Medicine and Hygiene, Vol. 64 No. 2 (2023): Vol. 64 No. 2 (2023)
Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth
Creators: name: Mayer-Davis, E. J.
name: D’Agostino, R.
name: Marcovina, S.
name: Hamman, R. F.
name: Dolan, L. M.
name: Dabelea, D.
name: Lawrence, J. M.
name: Florez, J. C.
name: McAteer, J. B.
name: Hernandez, A. M.
name: Pihoker, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been associated with type 2 diabetes in adults. However, it is not known whether TCF7L2 variation increases the risk of early onset type 2 diabetes. Using a case–control design, we examined whether the reported variants [rs12255372 (T/G) and rs7903146 (T/C)] are associated with type 2 diabetes in SEARCH for Diabetes in Youth study participants.