cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Begehren in Barbara Frischmuths Roman "die Klosterschule"
Creators: name: Köberl, Katharina Sofie
Year: 2021

description: Die vorliegende Masterarbeit zeigt und diskutiert konstruierte Begehrensstrukturen im Roman Die Klosterschule von Barbara Frischmuth. Der dafür ausgewählte gendertheoretische Ansatz verbindet im theoretischen Teil Ansätze Jacque Lacans und des französischen Feminismus‘ sowie philosophische Überlegungen von Michel Foucault und Judith Butler zum Thema Begehren. Anhand herausgearbeiteter Kriterien werden entsprechende Passagen im Buch mit der Methode des „close readings“ analysiert und interpretiert. Die zentralen Ergebnisse der Arbeit zeigen, dass die Begehrensstrukturen der Mädchen in der Klosterschule mit Hilfe von Körperfeindlichkeit, einer unterdrückenden Sprachdoktrin und Lustfeindlichkeit klar normiert, und im Sinne des „doing genders“ erzeugt werden. Die Klosterschüler*innen dürfen zu keiner körperlichen und sprachlichen Selbsterfahrung kommen, womit ihnen Subjektivität und eigene Begehrensstrukturen verwehrt bleiben sollen. Dennoch findet die Ich-Erzählerin einen Weg sich in ihrem Denken, ihrer Fantasie und ihrem Begehren auszudrücken. Dadurch entstehen Spannungen zwischen den Werten der Klosterschule, die über die Sprache sichtbar gemacht werden und den individuellen Entscheidungen der Hauptfigur. Die Klosterschule kann als sprachkritischer Roman gelesen werden, der bigotte, frauenfeindliche und intolerante Strukturen einer Bildungsinstitution und ihrer Gesellschaft sichtbar macht.
Non-divergent representation of non-Hermitian operator near the exceptional point with application to a quantum Lorentz gas
Creators: name: Hashimoto, Kazunari
name: Kanki, Kazuki
name: Hayakawa, Hisao
name: Petrosky, Tomio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We propose a non-singular representation for a non-Hermitian operator even if the parameter space contains exceptional points (EPs), at which the operator cannot be diagonalized and the usual spectral representation ceases to exist. Our representation has a generalized Jordan block form and is written in terms of extended pseudo-eigenstates. Our method is free from a divergence in the spectral representation at EPs, at which multiple eigenvalues and eigenvectors coalesce and the eigenvectors cannot be normalized. Our representation improves the accuracy of numerical calculations of physical quantities near EPs. We also find that our method is applicable to various problems related to EPs in the parameter space of non-Hermitian operators. We demonstrate the usefulness of our representation by investigating Boltzmann's collision operator in a one-dimensional quantum Lorentz gas in the weak coupling approximation.
Unity and Struggle v.4 no.3
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1975

description: This issue of Unity and Struggle volume 4, number 3, has a publication date of February 1975. Contributions of news articles, essays, illustrations, photographs, or advertisements are attributed to Afrikan Youth Movement for Liberation & Unity, Willie Brown, and Pedro Juan Soto.
Phalaena (Noctua) gamma 91
Creators: name: Linnaeus, Carolus
Publisher: name: Zenodo
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Noctuidae
Phalaena
Phalaena gamma

description: Gamma 91 P. Noctua spirilinguis cistata, alis deflexis: superioribus fuscis λ aureo inscriptis Fnt. scec. 873 Goed. ins. 2 t. 21 Alb. ins. t. 79 F. G. H. List. goed f. 14 Frisch. ins. 5. t. 15. Blank. ins. t. 8. f. N. P. Reaum. ins. 2. t. 26, 27, f. 5. Pet. gaz. t. 64. f. 6. Roes. ins. 1. phal. 3. t. 5. Raj. ins. 163 n. 17. Wilk. pap. 34. t. 2. a. 1. Mer. eur. 82. f. 78 Habitat in Abrotano, Boragine, Lactuca Larva geometrica, 12 - poda, viridis, subpilosa, nec ideo ad Geometras amandanda
description: Published as part of Carolus Linnaeus, 1758, gamma 91, pp. 513 in Systema naturae per regna tria naturae, secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis., Laurentii Salvii, Holmiae [= Stockholm]. on page 513, DOI: 10.5962/bhl.title.542
GraphWorld: A Novel Approach for Testing and Visualizing Graph-based Reinforcement Learning Algorithms
Creators: name: HRIDAY SAINATHUNI
name: KESHAV SUBRAMONIAN
name: Manshi Limbu
name: Xuesu Xiao
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Reinforcement Learning (RL) is a rapidly emerging branch of Machine Learning and computer science as a whole, based on the inherent reward system of biological beings. It is becoming increasingly popular to combine RL with engineering, specifically in the realm of motion-planning for autonomous robots. Cooperation between robotic systems is currently a vastly unexplored yet important field, as it is essential for the integration of autonomous robots in day-to-day life. Specifically, robotic systems can be represented in a graph framework using the concepts of nodes and edges, creating a more complex and descriptive method of inputs for neural networks in RL applications. In our study, we create an open-source, graph-based method of simulating agents, which can represent robotic systems in real-life. With the options of either tuning multiple parameters to fit a certain environment or creating completely randomized graph structures, our environment can simulate and provide dynamic visualizations for virtually any real life scenario. Therefore, our code offers a useful method for researchers to test the effectiveness and scalability of their graph network architectures.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Using Machine Learning to Improve Autonomous Robot Navigation on Vertically Challenging Terrain
Creators: name: PRISHA RACHAKONDA
name: HIMAGNYA ELAPROLU
name: Aniket Anand Datar
name: Chenhui Pan
name: Xuesu Xiao
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Autonomous robots can easily navigate flat surfaces like roads and sidewalks; however, when it comes to vertically challenging terrain, such as jagged rocks in off-road conditions, current robots tend to struggle. In order to address this problem, our research utilized machine learning (teaching a robot to make optimal decisions based on expert human demonstration). We built a four-wheel robot (crawler), constructed from a Traxxas chassis, with the following elements added to it: an Arduino Mega 2560, a Microsoft Azure Kinect RGB-D camera, an NVIDIA Jetson ORIN NX onboard computer, and a 6-volt servo. We then used this crawler to collect data by manually driving it over a bed of rocks and recording an elevation map generated by the RGB-Dcamera. In addition to mapping, each time we drove the robot over a bed of rocks, we recorded factors such as speed, odometry, and the state of its differentials (either locked or unlocked). Our lab will generate a neural network with the data collected and use it to train the crawler to traverse similarly difficult terrain autonomously in the future. By teaching it to recognize the best paths and courses of action on such terrain, the possibility of the robots’ ability for autonomous navigation creates more opportunities for the application of robotics in the real world.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Biorisk Management Case Study: National Institute for Public Health and the Environment
Creators: name: Bleijs, Rik
name: Brink, Kathryn
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Risk management

description: The National Institute for Public Health and the Environment (RIVM) Biosecurity Office is the expert information and advisory body for high-risk pathogens, knowledge, information, and technologies for the Dutch government. The Biosecurity Office provides support to biosafety officers and researchers in the Netherlands through awareness raising activities and the development of biosecurity tools. These tools include the Dual-Use Quickscan, which is the focus of this case study. Through its activities, the Biosecurity Office:
• raises awareness and promotes discussion between researchers and biosafety officers about dual-use risks.
• works closely with researchers and biosafety officers to understand risks “on the ground.”
• leverages existing resources to create streamlined risk assessment tools.
title: Baustelle im Diskurs
Creators: name: Voser, Sandra
Year: 2021

description: Die Masterarbeit analysiert die Kontroverse um die Neugestaltung der Wiener Mariahilfer Straße aus diskursanalytischer Sicht und begreift sie als symbolische Bedeutungsproduktion in Verwobenheit mit spezifischen Praktiken und materiellen Arrangements. Wie wird das Projekt urbaner Transformation vor und während des Umbaus medial dargestellt? Und inwiefern beeinflusst diese diskursive Ordnungsmaschine die Wahrnehmung der NutzerInnen des neugestalteten Stadtraums zum Zeitpunkt seiner Fertigstellung? Um die gesellschaftlichen Prozesse der Erzeugung, vorübergehenden Stabilisierung und Transformation von Wissen zu untersuchen, die soziale und räumliche Wirklichkeiten hervorbringen, wurde ein eigenes Verfahren entwickelt. Die mediale Diskursanalyse differenziert zwischen einem visionären Leitdiskurs und einem entlarvenden Gegendiskurs. Die exemplarische Rekonstruktion diskursiver Praktiken stellt eine ungleiche Verteilung von Macht und Ressourcen fest, offenbart aber auch eine wechselseitige Beeinflussung der eingesetzten Legitimierungsstrategien und Mitteln der Hegemoniebildung. Die dazugehörigen Deutungsmuster imaginieren und konstituieren den physischen Raum kontradiktorisch. Während das Vorhaben durch eine dystopische Risikoerzählung in virtuellen Resonanzräumen angegriffen wird – unterstützt von politisierten Lebensgefühlen und medienökonomischen Entwicklungen –, strebt die offizielle Chancenerzählung danach, die inhaltlichen Kritikpunkte einzuverleiben. Dabei kommt es zur Vermengung heterogener Wissensbestände, ohne dass die eine oder andere ideologische Einstellung ein stabiles Dominanzverhältnis entfalten kann. So hat die Triangulation mit einer Befragung der NutzerInnen der umgestalteten Straße ausgehandelte Codes des hegemonialen Narrativs und der oppositionellen Position detektiert. Ausgewählte Passagen aus den qualitativen Interviews wurden ausgehend von den kulturwissenschaftlichen Interpretationen zu einer eigenen Erzählung verdichtet und in Form einer Radiosendung vermittelt.
SU(4) harmonic superspace and supersymmetric gauge theory
Creators: name: Zupnik, B. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the harmonic-superspace formalism in the $N=4$ supersymmetry using the $SU(4)/SU(2)\times SU(2)\times U(1)$ harmonics which was earlier applied to the abelian gauge theory. The N=4 non-abelian constraints in a standard superspace are reformulated as the harmonic-superspace equations for two basic analytic superfields: the independent superfield strength W of a dimension 1 and the dimensionless harmonic gauge 4-prepotential V having the $U(1)$ charge 2. These constraint equations I manifestly depend on the Grassmann coordinates $θ$, although they are covariant under the unusual N=4 supersymmetry transformations. We analyze an alternative harmonic formalism of the supergauge theory for two unconstrained nonabelian analytic superfields W and V. The gauge-invariant action A(W,V) in this formalism contains $θ$ factors in each term, it is invariant under the $SU(4)$ automorphism group. In this model, the interaction of two infinite-dimensional N=4 supermultiplets with the physical and auxiliary fields arises at the level of component fields. The action A(W,V) generate analytic equations of motion II alternative to the harmonic-superspace superfield constraints I. Both sets of equations give us the equivalent equations for the physical component fields of the $N=4$ gauge supermultiplet, they connect auxiliary and physical fields of two superfields. The nonlinear effective interaction of the abelian harmonic superfield W is constructed.
description: 21 pages, v2: corrected version
ФОРМИРОВАНИЕ ПРОФЕССИОНАЛЬНЫХ КОМПЕТЕНЦИЙ СТУДЕНТОВ-ЭКОЛОГОВ, КАК ФАКТОР УСПЕШНОСТИ БУДУЩЕГО СПЕЦИАЛИСТА
Creators: name: А.С. Данильченко
name: К.А. Турушева
name: В.Ф. Торосян
Publisher: name: Zenodo
Year: 2025

description: Статья посвящена анализу формирования профессиональных компетенций студентов-экологов как важного фактора их успешности в будущей профессиональной деятельности. В статье рассматриваются ключевые аспекты образовательного процесса, включая теоретическую подготовку, практическую деятельность, междисциплинарный подход и использование инновационных технологий. Охарактеризована роль личностных качеств, таких как критическое мышление, инициативность и способность работать в команде, в становлении квалифицированных специалистов. Автор подчеркивает, что интеграция знаний из различных областей, а также развитие практических навыков через участие в реальных экологических проектах, способствуют подготовке успешных экологов. Статья также акцентирует внимание на важности постоянного профессионального развития и адаптации к изменениям в экологической сфере.
Evaluation of differential G-protein subunit markers for HIV latent infection in Jurkat and A3R5.7 cells
Creators: name: SAMUEL LI
name: LUKE MEHTA
name: Chillin, Linda
name: Tiwari, Sameer
name: Yuntao Wu
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Human immunodeficiency virus (HIV) infects helper T-cells by binding to the CD4 and CCR5/CXCR4 receptors for viral entry. The available antiretroviral therapy (ART) prevents progression towards acquired immunodeficiency syndrome (AIDS), but interruption of ART causes HIV rebound. This rebound is due to latent HIV reservoirs. There is no diagnostic method available to detect latently infected T-cells. CCR5 and CXCR4 are G-protein coupled receptors (GPCRs), which regulate the activation of G-proteins. Our prevous studies have shown that during viral entry, HIV uses CXCR4/CCR5 to activate G-proteins to facilitate infection. We are interseted in knowing whether the establishment of HIV reservoir in T cells can alter T cell G-proteins to facilitate viral persistence. G-proteins are heterotrimers of α, β, and γ subunits, each subunit performs different signaling roles in cells. Our lab developed a Multiplex G-protein profiling system. This system can identify G-protein subunits expressed in lymphocytes. We profiled G-proteins in HIV-infected cells and uninfected cells. Lymphocytes were infected with HIV-1 for five days. p24 expression was then analyzed by intracellular staining using flow cytometry. Lymphocytes showed p24 expression and were prepared for RNA extraction. RNA from cells is then used for our Multiplex G-Protein profiling system. The expression of G-protein subunits was then analyzed by gel-electrophoresis. The identification of the specific G-proteins subunits and the pattern expressed in infected HIV cells may be a powerful tool for detecting HIV latent reservoirs.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Unity and Struggle v.4 no.4
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1975

description: This issue of Unity and Struggle volume 4, number 4, has a publication date of March 1975. Contributions of news articles, essays, illustrations, photographs, or advertisements are attributed to Trevor Munroe, Mao Tse Tung, Nicholas Guillen, Horace Campell, and Amiri Baraka.
Branching Fraction of the Decay $B^+ \to \pi^+ \tau^+ \tau^-$ and Lepton Flavor Universality Test via the Ratio $R_\pi (\tau/\mu)$
Creators: name: Ali, Ahmed
name: Parkhomenko, Alexander Ya.
name: Parnova, Irina M.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: lepton, flavor, universality
branching ratio, ratio
lepton, flavor
neutral current, flavor changing
flavor, universality
psi(3685)
semileptonic decay
BELLE
decay rate
electroweak interaction
parametrization
LHC-B
CERN LHC Coll
Hamiltonian formalism
form factor

description: Among (semi)leptonic rare $B$-decays induced by the $b \to d$ flavor changing neutral current, the decay $B^+ \to \pi^+ \mu^+ \mu^-$ is the only one observed so far experimentally. Related decays involving the $e^+e^-$ and $\tau^+ \tau^-$ pairs are the targets for the ongoing experiments at the LHC, in particular LHCb, and Belle II. The muonic and electronic semileptonic decays have almost identical branching fractions in the Standard Model (SM). However, the tauonic decay $B^+ \to \pi^+ \tau^+ \tau^-$ differs from the other two due to the higher reaction threshold which lies slightly below the $\psi (2S)$-resonance. We present calculations of the ditauon ($\tau^+ \tau^-$) invariant-mass distribution and the branching fraction ${\rm Br} (B^+ \to \pi^+ \tau^+ \tau^-)$ in the SM based on the Effective Electroweak Hamiltonian approach, taking into account also the so-called long-distance contributions. The largest theoretical uncertainty in the short-distance part of the decay rates is due to the $B \to \pi$ form factors, which we quantify using three popular parametrizations. The long-distance contribution can be minimized by a cut on the ditauon mass $m_{\tau^+ \tau^-} > M_{\psi (2S)}$. Once available, the branching fractions in the tauonic and muonic (and electronic) modes provide stringent test of the lepton flavor universality in the $b \to d$ transitions. We illustrate this by calculating the ratio $R_\pi (\tau/\mu) \equiv {\rm Br} (B^+ \to \pi^+ \tau^+ \tau^-)/{\rm Br} (B^+ \to \pi^+ \mu^+ \mu^-)$ in the SM for the total and binned ratios of the branching fractions.
On the prime graph of simple groups
Creators: name: Burness, Timothy C.
name: Covato, Elisa
Publisher: name: arXiv
Year: 2014
Subjects: subject: Group Theory (math.GR)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Let $G$ be a finite group, let $π(G)$ be the set of prime divisors of $|G|$ and let $Γ(G)$ be the prime graph of $G$. This graph has vertex set $π(G)$, and two vertices $r$ and $s$ are adjacent if and only if $G$ contains an element of order $rs$. Many properties of these graphs have been studied in recent years, with a particular focus on the prime graphs of finite simple groups. In this note, we determine the pairs $(G,H)$, where $G$ is simple and $H$ is a proper subgroup of $G$ such that $Γ(G) = Γ(H)$.
description: 11 pages; to appear in Bull. Aust. Math. Soc
First-principles study of hydrogen-bonded molecular conductor $κ$-H$_3$(Cat-EDT-TTF/ST)$_2$
Creators: name: Tsumuraya, Takao
name: Seo, Hitoshi
name: Kato, Reizo
name: Miyazaki, Tsuyoshi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We theoretically study hydrogen-bonded molecular conductors synthesized recently, $κ$-H$_3$(Cat-EDT-TTF)$_2$ and its diselena analog, $κ$-H$_3$(Cat-EDT-ST)$_2$, by first-principles density-functional theory calculations. In these crystals, two H(Cat-EDT-TTF/ST) units share a hydrogen atom with a short O--H--O hydrogen bond. The calculated band structure near the Fermi level shows a quasi-two-dimensional character, with a rather large interlayer dispersion due to the absence of insulating layers in contrast with conventional molecular conductors. We discuss effective low-energy models based on H(Cat-EDT-TTF/ST) units and its dimers, respectively, where the microscopic character of the orbitals composing them are analyzed. Furthermore, we find a stable structure which is different from the experimentally determined structure, where the shared hydrogen atom becomes localized to one of the oxygen atoms, in which charge disproportionation between the two types of H(Cat-EDT-TTF) units is associated. The calculated potential energy surface for the H atom is very shallow near the minimum points, therefore the probability of the H atom can be delocalized between the two O atoms.
description: 10 pages, 8 figures
Quantitative Analysis of Strabismus Misalignment
Creators: name: CHARLOTTE GABRIEL
name: Chang, Thomas
name: Wei, Qi
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Strabismus is a binocular misalignment disorder in which the two eyes are not focused at the same target. Strabismus affects approximately 1 of 50 people, causing blurry and double vision as a result of the brain’s reception of differing images from the affected and non-affected eyes. Superior oblique palsy (SOP) occurs due to weakening of the superior oblique muscle and is a common cause of vertically-imbalanced strabismus. SOP is treated surgically. However, a lack of quantitative, long-term analysis results in lesser knowledge about the regression of strabismus post-surgery. Throughout this study, Hess Screen Charts, which mapped SOP-affected patients’ misaligned vision at 21 standardized eye positions, were translated digitally to obtain measured eye position angles and then analyzed at three time periods in the treatment process. These samples included pre-surgery, immediately post-surgery, and a post-post surgery period ranging from approximately 5-208 weeks. Then, the error between each standardized and actual eye position was calculated using three metrics: horizontal, vertical, and composite. Finally, these errors were averaged for each of the patients to examine the effects of the corrective surgery and regression of SOP misalignment post-operatively.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Additional file 2 of Professionalism in traditional Chinese medicine (TCM) practitioners: a qualitative study
Creators: name: Kwan, Yu Heng
name: Chooi, Sarah
name: Sungwon Yoon
name: Ang, Xiang Ling
name: Phang, Jie Kie
name: Hwee Ling Koh
name: Thumboo, Julian
name: Swee Cheng Ng
name: Fong, Warren
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 2.
Generic axion Maxwell equations: path integral approach
Creators: name: Sokolov, Anton V.
name: Ringwald, Andreas
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: strong interaction, CP
energy, interaction
photon, regeneration
energy, low
CP, violation
axion
Maxwell equation
path integral
signature
dyon
electromagnetic field
spontaneous symmetry breaking
U(1)
axial
Peccei-Quinn
structure

description: Using the path integral approach, we derive the low energy interactions between axions and electromagnetic field that arise in models with heavy dyons charged under a spontaneously broken global axial $U(1)$ symmetry. Hence, we obtain generic axion-Maxwell equations relevant for experimental searches. We find that the structure of the axion Maxwell equations could be significantly different compared to what is normally assumed in the literature, as the derived equations feature new axion-dependent terms including CP-violating ones. The new terms can reconcile the Peccei-Quinn solution to the strong CP problem with astrophysical axion hints, as well as give unique signatures in light-shining-through-wall and haloscope experiments. Moreover, via the latter signatures, these experiments can indirectly probe the existence of heavy dyons.
Enhanced DRT estimation using prior knowledge
Creators: name: T Malkow
Publisher: name: Zenodo
Year: 2022
Subjects: impedance, DRT, Mellin transform, logarithmic Fourier transform, PEM fuel cell

description: In recent decades, the analysis of impedance data by their numerical transformation into the domain of relaxation times to yield distributions of uncorrelated relaxation times (DRT) has gained widespread popularity for characterising electrochemical power and conversion devices such as batteries, capacitors, electrolysis and fuel cells. Information acquired by DRT analysis supplements the information known from measurements and the physical and electrochemical characteristics of the studied device.
 Various pre-compiled numerical tools for the inversion of the underlying integral equation of the DRT impedance are nowadays readily available to estimate the DRT from measured (or modelled) data. The only significant effort in such DRT estimation is yet to adjust one or another tuning parameter especially when employing regularisation methods.
 Virtually all these tools assume the DRT is real valued, which is unfortunately not the case when the data are not exactly of the same nature as that of the employed integral kernel. This is regrettably a fact little known even among those familiar and well versed with DRT analysis. The use of prior knowledge that is, valid information independent of the data, is rarely utilised to full extent for constraining numerically the solution space of the resulting DRT.
Additional file 1 of Chromosomal instability in the prediction of pituitary neuroendocrine tumors prognosis
Creators: name: Lasolle, Hélène
name: Mad-Hélénie Elsensohn
name: Wierinckx, Anne
name: Eudeline Alix
name: Bonnefille, Clément
name: Vasiljevic, Alexandre
name: Cortet, Christine
name: Decoudier, Bénédicte
name: Sturm, Nathalie
name: Gaillard, Stephan
name: Ferrière, Amandine
name: Roy, Pascal
name: Jouanneau, Emmanuel
name: Bertolino, Philippe
name: Bardel, Claire
name: Sanlaville, Damien
name: Raverot, Gérald
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1
Variational Quantum Algorithm for Quantum Dynamics
Creators: name: JACOB MAURER
name: Tsakanikas, Joachim
name: Avin Buddheesha
name: Jayasundara Seneviratne
name: Wang, Fei
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Simulating quantum dynamics on classical computers remains challenging on classical computers due to the exponentially large Hilbert space. On the other hand, quantum computers are naturally suited for quantum simulations. This paper explores the state-of-the-art variational quantum algorithm for simulating quantum dynamics using near-term quantum devices. In essence, the most expensive part of the calculation is done on the quantum machine which can take advantage of the quantum speed up. The relatively straight forward optimization process is conducted on a classical computer. This hybrid approach makes best use of the two computing architectures to solve the challenging problems in quantum dynamic simulation. We apply the algorithm to the electron tunneling dynamics in chemical reactions. The workflow includes constructing a Hamiltonian that represents the energy levels of the system and the electronic coupling strength, designing quantum circuits, and running the algorithm on real quantum devices. The algorithm design and its application will demonstrate practical use cases of quantum computing in quantum simulation.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
The CMS di-photon excess at 95 GeV in view of the LHC Run 2 results
Creators: name: Biekötter, T.
name: Heinemeyer, S.
name: Weiglein, G.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: final state, two-photon
Higgs particle
GeV
CERN LHC Coll
CMS
Yukawa
CERN LEP Stor
singlet
supersymmetry
ATLAS
doublet

description: The CMS collaboration has recently reported the results of a low-mass Higgs-boson search in the di-photon final state based on the full Run 2 data set with refined analysis techniques. The new results show an excess of events at a mass of about 95 GeV with a local significance of $2.9\,\sigma$, confirming a previously reported excess at about the same mass and similar significance based on the first-year Run 2 plus Run 1 data. The observed excess is compatible with the limits obtained in the corresponding ATLAS searches. In this work, we discuss the di-photon excess and show that it can be interpreted as the lightest Higgs boson in the Two-Higgs doublet model that is extended by a complex singlet (S2HDM) of Yukawa types II and IV. We show that the second-lightest Higgs boson is in good agreement with the current LHC Higgs-boson measurements of the state at 125 GeV, and that the full scalar sector is compatible with all theoretical and experimental constraints. Furthermore, we discuss the di-photon excess in conjunction with an excess in the $b \bar b$ final state observed at LEP and an excess observed by CMS in the di-tau final state, which were found at comparable masses with local significances of about $2\sigma$ and $3\sigma$, respectively. We find that the $b \bar b$ excess can be well described together with the di-photon excess in both types of the S2HDM. However, the di-tau excess can only be accommodated at the level of $1\sigma$ in type IV. We also comment on the compatibility with supersymmetric scenarios and other extended Higgs sectors, and we discuss how the potential signal can be further analyzed at the LHC and at future $e^+e^-$ colliders.
Using a Convolutional Neural Network to Classify Nanobodies on Neutralizing Ability Using Sequence Data for SARS-Cov-2
Creators: name: NITHYA VINODH
name: Losif Vaisman
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: In order to combat the growing number of viral diseases, scientists have found a variety of new technologies to help reduce the risk of contracting a disease. Of the many that have been found over the last few years, one of the most promising are nanobodies. Nanobodies, much like antibodies, are able to bind to viruses. However, they consist only of a heavy chain variable domain, making them significantly smaller than antibodies and far more stable (Bao et al., 2021). They are also easier to produce synthetically, making them a viable alternative to current monoclonal antibody therapies. Certain nanobodies have the ability to neutralize antigens by binding to the outer regions of the virus and preventing it from entering cells and replicating. However, there are no ways to predict whether a given nanobody would neutralize a given virus without expensive wet lab testing, which is expensive and time consuming, Bioinformatics, however, provides tools that can speed up the discovery of neutralizing nanobodies. While methods exist to determine nanobody structure based on sequence, none exist to classify nanobodies based on neutralization ability. To address this, a CNN was created in order to classify nanobodies' neutralizing abilities using only sequence data for SARS-Cov-2. This yielded a preliminary model with a 69.4% accuracy in predicting the neutralization activity of nanobodies against SARS-Cov-2, which indicates with further testing, an accurate model to determine neutralization activity can be created.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Assessing a Correlation between Predicted Protein Stability and Antibiotic Resistance of Beta-Lactamase Enzymes
Creators: name: SARINA LI
name: SHARANYA TUMMA
name: Vaisman, Iosif
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Rates of antibiotic resistance in pathogenic bacteria have risen significantly in the past decades, rendering many widely used beta-lactam antibiotics ineffective. The main resistance mechanisms of these bacteria are linked to beta-lactamase enzymes that hydrolyze rings within beta-lactam antibiotics. As a result, predicting the impact of mutations in beta-lactamases can be critical to developing effective antibiotic treatments. The aim of our research is to investigate how antibiotic resistance correlates with protein stability changes. Our research employs computational machine learning models that predict changes in protein stability, including AUTOMUTE 2.0, MAESTROweb, PROST, and MUpro. We compiled a dataset of 83 single residue mutations with known antibiotic resistance degrees. Using these models, we predicted stability scores (ΔΔG) for each mutant in the dataset, as well as classified each mutant by residue depth and secondary structure using Swiss PDB Viewer and PDB database, respectively. Lastly, the analysis of the results indicated that the correlation between the enzyme stability and drug resistance is not statistically significant. Additional features for drug resistance modeling should be considered.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Perspective on completing natural inflation
Creators: name: Choi, Ki-Young
name: Kim, Jihn E.
name: Kyae, Bumseok
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a perspective on the inflation paths in 2-, 3-,,, N-flation models based on the ultraviolet completion in heterotic string theory, where a number of grand unification scale axions are used. The number of non-Abelian gauge groups for a natural inflation is restricted in string compactification, and we argue that the most plausible completion of natural inflation from a theory perspective is the 2-flation.
description: 5 pages, 1 eps figure
CP violation with a dynamical Higgs
Creators: name: Gavela, M. B.
name: Gonzalez-Fraile, J.
name: Gonzalez-Garcia, M. C.
name: Merlo, L.
name: Rigolin, S.
name: Yepes, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We determine the complete set of independent gauge and gauge-Higgs CP-odd effective operators for the generic case of a dynamical Higgs, up to four derivatives in the chiral expansion. The relation with the linear basis of dimension six CP-odd operators is clarified. Phenomenological applications include bounds inferred from electric dipole moment limits, and from present and future collider data on triple gauge coupling measurements and Higgs signals.
description: 41 pages, 3 figures; V2: citations added, typos corrected, version published on JHEP
Analysis of CFTR Gene Mutations in Cystic Fibrosis
Creators: name: PRANAV PREM
name: Vaisman, Iosif
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Cystic Fibrosis is a genetic disorder caused by mutations in the CFTR gene. Despite significant advances in recent years, the specific molecular mechanisms of how different CFTR mutations affect disease severity remain unclear. In this study, we analyzed various CFTR mutations to show their impact on Cystic Fibrosis phenotypes, geographical regions, structural modifications in the CFTR protein, and potential functional implications. A statistical association between mutation type and clinical significance was assessed, showing that some mutation types like missense mutations were more likely to be pathogenic. Geographical analysis indicated variant frequencies were distinct across various global populations, hinting towards the role of genetic drift and possibly the Founder Effect from Northern Europeans. The preliminary structural analysis provided insights into how specific mutations, like F508del, might alter the protein conformation affecting its function. Employing machine learning tools, we analyzed the functional implications of specific mutations, helping to establish a genotype-phenotype correlation. Our findings provide a multi-dimensional view of CFTR mutations which enhances our understanding of Cystic Fibrosis and potentially help in personalized patient care.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
title: Spezielle elektrische Messgeräte in der historischen Sammlung der Fakultät für Physik
Creators: name: Leschnik, Alfred
Year: 2021

description: In der historischen Sammlung der Fakultät für Physik gibt es zahlreiche elektrostatische Messgeräte und Drehspulspiegelgalvanometer, die einige Jahrzehnte vor 1900 oder um 1900 verwendet wurden. Das Ziel der vorliegenden Masterarbeit ist es Aufbau und Funktion einiger dieser Messgeräte zu analysieren und sie auch im Experiment einzusetzen. Voll einsatzfähig erwies sich das Elektrostatische Voltmeter nach Thomson in einem Messbereich von 0 bis 10 kV. Ein näher untersuchtes Binantenelektrometer von Bartels war nicht mehr einsatzfähig. Es konnte soweit restauriert werden, dass ein kleiner Ausschlag merkbar war, weiteren Optimierungsversuchen hielten leider die filigranen mehr als hundert Jahre alten Bernsteinisolationen und auch die dünne Folie der zweiteiligen Nadel nicht stand. Auch der Versuch, ein Einfadenelektrometer nach Wulf von Günther und Tegetmeyer zu restaurieren scheiterte an fehlenden Materialien und handwerklichem Knowhow. Ein mit Quecksilber zu betreibendes Torsions-Elektrodynamometer wurde nur theoretisch behandelt. Näherungsweise berechnete Werte für das Drehmoment bestätigen die Sinnhaftigkeit der Konstruktion aus dem Jahr 1883. Durchaus erfolgreich waren die Experimente mit den fünf ausgewählten Drehspulspiegelgalvanometern von Hartmann & Braun, Siemens & Halske sowie Kipp & Zonen. Die Transportsicherung, Galvanometerwiderstand, der aperiodische Grenzfall und gute Linearität konnten für die jeweiligen Geräte herausgefunden werden. Die kleinste gefundene Spannungskonstante betrug 3 μV bei einem Skalenabstand von einem Meter.
Efficient negative-weight elimination in large high-multiplicity Monte Carlo event samples
Creators: name: Andersen, Jeppe R.
name: Maier, Andreas Martin
name: Maître, Daniel
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: multiplicity, high
vector boson, production
efficiency
Monte Carlo
enhancement

description: We demonstrate that cell resampling can eliminate the bulk of negative event weights in large event samples of high multiplicity processes without discernible loss of accuracy in the predicted observables. The application of cell resampling to much larger data sets and higher multiplicity processes such as vector boson production with up to five jets has been made possible by improvements in the method paired with drastic enhancement of the computational efficiency of the implementation.
Prediction of Blood Brain Barrier Penetrating Peptides Using BERT Feature Embeddings Fused With Physiochemical Properties Representation.
Creators: name: MYTHREYA DHARANI
name: Vaisman, Iosif
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: As the largest site for blood-brain interchange, the blood-brain barrier (BBB) is distinctly composed to limit fenestrations, which allows for regulation of neurotransmitters, plasma macromolecules, neurotoxins, and unwanted substances in general from entering the central nervous system (CNS). Although peptides were historically thought of as not being able to permeate BBB, recent research has established that several can cross, and are now of interest as drugs and treatment conjugates. Experimental methods for study the BBB penetrating peptides can be expensive are time consuming. Machine learning methods provide a promising alternative, but current approaches neglect to utilize the contextual information in the peptide sequences themselves. Thus, a novel algorithm considering both the protein sequence embeddings and the physicochemical features of the peptides themselves was developed. Sequence embeddings were constructed using ProteinBERT, a bidirectional transformer model, and five physicochemical feature vectors were generated with multiple scripts and database extractions. A multi-layer perceptron was trained on a dataset consisting of around 500 peptides, filtered for similarity by CD-HIT. The model had an 84% accuracy, outperforming machine learning algorithms for BBB peptide permeability prediction. Thus, this model has widespread implications, and can be utilized for efficient screening of peptide development, in order to create effective drugs for neurological and other conditions.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Predicting optimal catalytic temperature of enzymes using Graph Convolutional Networks
Creators: name: LUKE MEI
name: Vaisman, Iosif
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: As enzymes that are stable at higher temperatures play an important role in industrial applications for enhancing reaction rates in biochemical processes, accurate prediction of optimal catalytic temperature (Topt) of enzymes can be valuable in biotechnology. Furthemore, the number of experimentally determined Topt values are limited as they are difficult and time consuming to retrieve. Existing enzyme temperature optima prediction models are based on traditional machine learning algorithms and only utilize protein sequence information. Here, we introduce DeepTOP, a Graph Convolutional Network for predicting Topt of enzymes by utilizing both protein structure as well as protein sequence features extracted using a pre-trained language model. A dataset of 2917 enzymes with experimental Topt was obtained from a previous study that produced the state of the art model. Out of the 2917 enzymes, features were extracted from 2859 with alpha fold predicted three dimensional structure. DeepTOP exhibits near state of the art performance with R^2 of 0.45 and mean squared error (MSE) of 247.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
Sequence-based Models of Antimicrobial Peptide Stability
Creators: name: JASMINE MA
name: Vaisman, Iosif
Publisher: name: Journal of Student-Scientists' Research
Year: 2023

description: Antimicrobial peptides (AMPs) are peptides commonly found in organism immune systems, fighting off bacterial, fungal, and other infections. Their potential for application in the medical field includes combating antibacterial resistance and developing novel oral ingestible options to decrease toxicity in infection treatment. A major difficulty in working with AMPs is their high instability and expensive storage procedures, which create challenges in lab environments and experimental procedures. Additionally, high AMP instability can reduce effectiveness and create safety risks in medicinal applications. Previous models created do not specifically target factors that affect AMP stability, such as chemical structure, size, shape, hydrophobicity, temperature, and more. To holistically scale the results of the model runs, a new "stability score" system ranging from 0 (least stable) to 1 (most stable) was developed to easily determine the st ability of the inputed sequence. Two key tools used in this study included the DeepSTABp model for assessing thermal stability and the ThermoFisher Peptide Synthesis and Proteotypic Peptide Analyzing Tool for evaluating chemical composition. Data samples of amino acid sequences were selected from various thermal stability model datasets with a uniform size distribution. The DeepSTABp results were further complemented by the Peptide Analyzing Tool to analyze chemical composition and compatibility. Results were then analyzed and scaled based on their hydrophobicity and thermal stability, resulting in a stability score ranging from 0 to 1. Through this study, stability scores for amino acid prediction were standardized and evaluated based on multiple factors.
description: Journal of Student-Scientists' Research, Vol. 5 (2023)
MPEC 2024-S11 : COMET P/2024 R3 (PANSTARRS)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: COMET P/2024 R3 (PANSTARRS)

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Vector rogue waves and dark-bright boomeronic solitons in autonomous and non-autonomous settings
Creators: name: Mareeswaran, R. B.
name: Charalampidis, E. G.
name: Kanna, T.
name: Kevrekidis, P. G.
name: Frantzeskakis, D. J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: In this work, we consider the dynamics of vector rogue waves and dark-bright solitons in two-component nonlinear Schrödinger equations with various physically motivated time-dependent nonlinearity coefficients, as well as spatio-temporally dependent potentials. A similarity transformation is utilized to convert the system into the integrable Manakov system and subsequently the vector rogue and dark-bright boomeron-like soliton solutions of the latter are converted back into ones of the original non-autonomous model. Using direct numerical simulations we find that, in most cases, the rogue wave formation is rapidly followed by a modulational instability that leads to the emergence of an expanding soliton train. Scenarios different than this generic phenomenology are also reported.
description: 15 pages, 8 figures, 1 table
HEJ 2.2: W boson pairs and Higgs boson plus jet production at high energies
Creators: name: Andersen, Jeppe R.
name: Ducloué, Bertrand
name: Hassan, Hitham
name: Elrick, Conor
name: Maier, Andreas Martin
name: Nail, Graeme
name: Paltrinieri, Jérémy
name: Papaefstathiou, Andreas
name: Smillie, Jennifer M.
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: energy, high
lepton, pair production
jet, production
W, production
Higgs particle, production
jet, multiplicity, high
jet, energy
Monte Carlo
interface
scattering
perturbation theory

description: We present version 2.2 of the High Energy Jets (HEJ) Monte Carlo event generator for hadronic scattering processes at high energies. The new version adds support for two further processes of central phenomenological interest, namely the production of a W boson pair with equal charge together with two or more jets and the production of a Higgs boson with at least one jet. Furthermore, a new prediction for charged lepton pair production with high jet multiplicities is provided in the high-energy limit. The accuracy of HEJ 2.2 can be increased further through an enhanced interface to standard predictions based on conventional perturbation theory. We describe all improvements and provide extensive usage examples. HEJ 2.2 can be obtained from https://hej.hepforge.org.