cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Optimal Public Expenditure with Inefficient Unemployment
Creators: name: Michaillat, Pascal
name: Saez, Emmanuel
Publisher: name: Zenodo
Year: 2019

description: This paper proposes a theory of optimal public expenditure when unemployment is inefficient. The theory is based on a matching model. Optimal public expenditure deviates from the Samuelson rule to reduce the unemployment gap (the difference between current and efficient unemployment rates). Such optimal "stimulus spending'' is described by a formula expressed with three sufficient statistics: the unemployment gap, the unemployment multiplier (the decrease in unemployment achieved by increasing public expenditure), and the elasticity of substitution between public and private consumption. When unemployment is inefficiently high and the multiplier is positive, the formula yields the following results. (a) Optimal stimulus spending is positive and increasing in the unemployment gap. (b) Optimal stimulus spending is zero for a zero multiplier, increasing in the multiplier for small multipliers, largest for a moderate multiplier, and decreasing in the multiplier beyond that. (c) Optimal stimulus spending is zero if extra public goods have no value, it becomes larger as the elasticity of substitution increases, and it completely fills the unemployment gap if extra public goods are as valuable as extra private goods.
title: Green waste addition to boosting solid-state anaerobic digestion of municipal solid waste for efficient methanogenesis and energy recovery
Creators: name: Wattananarong Markphan
Publisher: name: Asia-Pacific Journal of Science and Technology
publisherIdentifierScheme: ROR
Year: 2025
Subjects: Organic fraction municipal solid waste
Green waste, Co-digestion
Methane production
Microbial community

description: Asia-Pacific Journal of Science and Technology, 30, 1, 12 (11 pages)
MOESM3 of Characterization of resistance to a potent d-peptide HIV entry inhibitor
Creators: name: Smith, Amanda
name: Weinstock, Matthew
name: Siglin, Amanda
name: Whitby, Frank
name: J. Francis
name: Hill, Christopher
name: Eckert, Debra
name: Root, Michael
name: Kay, Michael
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 3. Effect of Q577R on C-peptide Inhibitors. Single-cycle viral infectivity assays in which HIV-1 HXB2 Env (WT and Q577R) pseudotyped HIV-1 with a luciferase reporter was used to infect HOS-LES cells in the absence or presence of six fivefold dilutions of the indicated C-peptide (in quadruplicate). The data are the average of two experiments with the standard deviation in parentheses.
Radiative decays of ϕ-meson and nature of light scalar resonances
Creators: name: Achasov, N. N.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Based on gauge invariance, we show that the new threshold phenomenon is discovered in the ϕradiative decays ϕ\toγa0\toγ\pi0ηand ϕ\toγf0\toγ\pi0\pi0. This enables to conclude that production of the lightest scalar mesons a0(980) and f0(980) in these decays is caused by the four-quark transitions, resulting in strong restrictions on the large Nc expansions of the decay amplitudes. The analysis shows that these constraints give new evidences in favor of the four-quark nature of a0(980) and f0(980) mesons.
description: 12 pages, 5 figures, revtex
MOESM10 of From spiral cleavage to bilateral symmetry: the developmental cell lineage of the annelid brain
Creators: name: Vopalensky, Pavel
name: Tosches, Maria
name: Achim, Kaia
name: Handberg-Thorsager, Mette
name: Arendt, Detlev
Publisher: name: figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 10: Figure S2. The consensus lineage tree of the episphere development from fertilization until 30 hpf. The previously described early cell lineage is highlighted in blue [26]. The black branches represent a consensus of three embryos. If one embryo differs from the remaining two, the tree topology based of the two embryos is shown in gray. The horizontal error bars at cell division time points represent the minimal and maximal time point observed for that cell division. The numbers rNNN (eg. r214) above the branch represent the unique cell ID that can be used to find/label the cell within the ImageJ/FIJI macro (Additional fileÂ 1: PduLineageMacroPackage.ijm). The annotations of the known differentiated cell types from TableÂ 1 are shown at the end points of the branches. See Fig.Â 2d for more details.
Stable integral simplicial volume of 3-manifolds
Creators: name: Fauser, Daniel
name: Loeh, Clara
name: Moraschini, Marco
name: Quintanilha, José Pedro
Publisher: name: arXiv
Year: 2019
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 55N10, 57N65, 57M27

description: We show that non-elliptic prime 3-manifolds satisfy integral approximation for the simplicial volume, i.e., that their simplicial volume equals the stable integral simplicial volume. The proof makes use of integral foliated simplicial volume and tools from ergodic theory.
description: 36 pages, no figures; minor changes made according to referee's suggestions; To appear in J. Topol
Using Digital Field Experiments To Elicit Risk Mitigation Behavioral Strategies For Disease Management Across Agricultural Production Systems
Creators: name: Clark, Eric M.
name: Merrill, Scott C.
name: Trinity, Luke
name: Bucini, Gabriela
name: Cheney, Nicholas
name: Langle-Chimal, Ollin
name: Shrum, Trisha
name: Koliba, Christopher
name: Zia, Asim
name: Smith, Julia M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Failing to mitigate propagation of disease spread can result in dire economic consequences for agricultural networks. Pathogens like Porcine Epidemic Diarrhea virus, can quickly spread among producers. Biosecurity is designed to prevent infection transmission. When considering biosecurity investments, management must balance the cost of protection versus the consequences of contracting an infection. Thus, an examination of the decision making processes associated with investment in biosecurity is important for enhancing system wide biosecurity. Data gathered from digital field experiments can provide insights into behavioral strategies and inform the development of decision support systems. We created an online digital experiment to simulate outbreak scenarios among swine production supply chains, where participants were tasked with making biosecurity investment decisions. In Experiment One, we quantified the risk associated with each participant's decisions and delineated three dominant categories of risk attitudes: risk averse, risk tolerant, and opportunistic. Each risk class exhibited unique approaches in reaction to risk and disease information. We also tested how information uncertainty affects risk aversion, by varying the amount of visibility of the infection as well as the amount of biosecurity implemented across the system. We found evidence that more visibility in the number of infected sites increases risk averse behaviors, while more visibility in the amount of neighboring biosecurity increased risk taking behaviors. In Experiment Two, we were surprised to find no evidence for differences in behavior of livestock specialists compared to Amazon Mechanical Turk participants. Our findings provide support for using digital field experiments to study how risk communication affects behavior, which can provide insights towards more effective messaging strategies.
Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors
Creators: name: Yetsko, Kelsey
name: Farrell, Jessica A.
name: Blackburn, Nicholas B.
name: Whitmore, Liam
name: Stammnitz, Maximilian R.
name: Whilde, Jenny
name: Eastman, Catherine B.
name: Ramia, Devon Rollinson
name: Thomas, Rachel
name: Krstic, Aleksandar
name: Linser, Paul
name: Creer, Simon
name: Carvalho, Gary
name: Devlin, Mariana A.
name: Nahvi, Nina
name: Leandro, Ana Cristina
name: DeMaar, Thomas W.
name: Burkhalter, Brooke
name: Murchison, Elizabeth P.
name: Schnitzler, Christine
name: Duffy, David J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/631/67
/631/158
/631/67/69
/631/67/70
/631/158/672
/38/1
/38/39
/38/91
/45
/96/95
article

description: Abstract: Sea turtle populations are under threat from an epizootic tumor disease (animal epidemic) known as fibropapillomatosis. Fibropapillomatosis continues to spread geographically, with prevalence of the disease also growing at many longer-affected sites globally. However, we do not yet understand the precise environmental, mutational and viral events driving fibropapillomatosis tumor formation and progression. Here we perform transcriptomic and immunohistochemical profiling of five fibropapillomatosis tumor types: external new, established and postsurgical regrowth tumors, and internal lung and kidney tumors. We reveal that internal tumors are molecularly distinct from the more common external tumors. However, they have a small number of conserved potentially therapeutically targetable molecular vulnerabilities in common, such as the MAPK, Wnt, TGFβ and TNF oncogenic signaling pathways. These conserved oncogenic drivers recapitulate remarkably well the core pan-cancer drivers responsible for human cancers. Fibropapillomatosis has been considered benign, but metastatic-related transcriptional signatures are strongly activated in kidney and established external tumors. Tumors in turtles with poor outcomes (died/euthanized) have genes associated with apoptosis and immune function suppressed, with these genes providing putative predictive biomarkers. Together, these results offer an improved understanding of fibropapillomatosis tumorigenesis and provide insights into the origins, inter-tumor relationships, and therapeutic treatment for this wildlife epizootic.
Impact of increasing the availability of healthier vs. less-healthy food on food selection: a randomised laboratory experiment
Creators: name: Pechey, Rachel
name: Sexton, Olivia
name: Codling, Saphsa
name: Marteau, Theresa M.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research Article
Health behavior, health promotion and society
Absolute-and-relative availability
Food selection
Socioeconomic position
Health inequalities
Response inhibition
Food appeal

description: Abstract: Background: Environmental cues shape behaviour, but few studies compare the impact of targeting healthier vs. less-healthy cues. One online study suggested greater impact on selection from increasing the number of less-healthy (vs. healthier) snacks. The current study aimed to: (1) extend the previous study by using physically-present snacks for immediate consumption; (2) explore responsiveness by socio-economic position; (3) investigate possible mediators (response inhibition, food appeal) of any socio-economic differences in selection. Methods: In a between-subjects laboratory experiment UK adults (n = 417) were randomised according to their ID number (without blinding) to one of three ranges of options: Two healthier, two less-healthy [“Equal”] (n = 136); Six healthier, two less-healthy [“Increased Healthier”] (n = 143); Two healthier, six less-healthy [“Increased Less-Healthy”] (n = 138). Participants completed measures of response inhibition and food appeal, and selected a snack for immediate consumption from their allocated range. The primary outcome was selection of a healthier (over less-healthy) snack. Results: The odds of selecting a less-healthy snack were 2.9 times higher (95%CIs:1.7,5.1) in the Increased Less-Healthy condition compared to the Equal condition. The odds of selecting a healthier snack were 2.5 times higher (95%CIs:1.5,4.1) in the Increased Healthier (vs. Equal) condition. There was no significant difference in the size of these effects (− 0.2; 95%CIs:-1.1,0.7). Findings were inconclusive with regard to interactions by education, but the direction of effects was consistent with potentially larger impact of the Increased Healthier condition on selection for higher-educated participants, and potentially larger impact of the Increased Less-Healthy condition for less-educated participants. Conclusions: A greater impact from increasing the number of less-healthy (over healthier) foods was not replicated when selecting snacks for immediate consumption: both increased selections of the targeted foods with no evidence of a difference in effectiveness. The observed pattern of results suggested possible differential impact by education, albeit not statistically significant. If replicated in larger studies, this could suggest that removing less-healthy options has the potential to reduce health inequalities due to unhealthier diets. Conversely, adding healthier options could have the potential to increase these inequalities. Trial registration: ISRCTN: ISRCTN34626166; 11/06/2018; Retrospectively registered.
Syzeuctus iampus Ugalde & Gauld 2002
Creators: name: González-Moreno, Alejandra
name: Bordera, Santiago
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Syzeuctus
Syzeuctus iampus

description: Syzeuctus iampus Ugalde & Gauld 2002
 Distribution. Neotropical (Costa Rica).
 Habitat. Coastal dune scrubland, savannah, dry forest.
 Phenology. Appendix I (Fig. 4).
 Studied material. MEXICO. Yucatán State, Ria Lagartos Biosphere Reserve, Ría Lagartos Station, Core II: 13–27.V.2009, 1 ♂. Cuyo Station, Cemetery: 16.V–03.VI.2008, 1 ♂; 24.VI–08.VII.2009, 1 ♀. Punta Meco: 28. VII–12.VIII.2008, 1 ♀, 8 ♂♂ (CCBA); 12–28.VIII.2008, 5 ♂♂; 28.VIII–10.IX.2008, 1 ♂; 10–24.IX.2008, 1 ♂; 29.IV–13.V.2009, 2 ♂♂; 13–27.V.2009, 1 ♂ (CEUA). Sacbo: 01–14.VII.2008, 1 ♀; 12–28.VIII.2008, 2 ♀; 08– 22.X.2008, 1 ♀ (CCBA). Tekal: 01–14.VII.2008, 2 ♀; 14–28.VII.2008, 2 ♀ (CEUA).
description: Published as part of González-Moreno, Alejandra & Bordera, Santiago, 2011, New records of Ichneumonidae (Hymenoptera: Ichneumonoidea) from Mexico, pp. 1-21 in Zootaxa 2879 (1) on page 4, DOI: 10.11646/zootaxa.2879.1.1, http://zenodo.org/record/5285972
title: Towards sustainable sugar industry in Thailand: Cost and benefit analysis
Creators: name: Suphaphat Kwonpongsagoon
Publisher: name: Asia-Pacific Journal of Science and Technology
publisherIdentifierScheme: ROR
Year: 2025
Subjects: Sustainable
Industry
Sugarcane
Sugar
Waste management
Cost
Benefit
Benefit-cost ratio (BCR)

description: Asia-Pacific Journal of Science and Technology, 30, 1, 13 (14 pages)
The asymptotic profile of an eta-theta quotient related to entanglement entropy in string theory
Creators: name: Males, Joshua
Publisher: name: arXiv
Year: 2019
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: In this paper we investigate a certain eta-theta quotient which appears in the partition function of entanglement entropy. Employing Wright's circle method, we give its bivariate asymptotic profile.
description: Corrected version of the published article, including corrections addressed in a forthcoming corrigendum
Anderson impurity model at finite Coulomb interaction U: generalized Non-crossing Approximation
Creators: name: Haule, K.
name: Kirchner, S.
name: Kroha, J.
name: Wölfle, P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present an extension of the non-crossing approximation (NCA), which is widely used to calculate properties of Anderson impurity models in the limit of infinite Coulomb repulsion $U\to\infty$, to the case of finite $U$. A self-consistent conserving pseudo-particle representation is derived by symmetrizing the usual NCA diagrams with respect to empty and doubly occupied local states. This requires an infinite summation of skeleton diagrams in the generating functional thus defining the ``Symmetrized finite-U NCA'' (SUNCA). We show that within SUNCA the low energy scale $T_K$ (Kondo temperature) is correctly obtained, in contrast to other simpler approximations discussed in the literature.
description: 7 pages, 6 figures
Domestication via the commensal pathway in a fish-invertebrate mutualism
Creators: name: Brooker, Rohan M.
name: Casey, Jordan M.
name: Cowan, Zara-Louise
name: Sih, Tiffany L.
name: Dixson, Danielle L.
name: Manica, Andrea
name: Feeney, William E.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/158/856
/631/158/853
/631/158/857
/704/829/826
article

description: Abstract: Domesticator-domesticate relationships are specialized mutualisms where one species provides multigenerational support to another in exchange for a resource or service, and through which both partners gain an advantage over individuals outside the relationship. While this ecological innovation has profoundly reshaped the world’s landscapes and biodiversity, the ecological circumstances that facilitate domestication remain uncertain. Here, we show that longfin damselfish (Stegastes diencaeus) aggressively defend algae farms on which they feed, and this protective refuge selects a domesticator-domesticate relationship with planktonic mysid shrimps (Mysidium integrum). Mysids passively excrete nutrients onto farms, which is associated with enriched algal composition, and damselfish that host mysids exhibit better body condition compared to those without. Our results suggest that the refuge damselfish create as a byproduct of algal tending and the mutual habituation that damselfish and mysids exhibit towards one another were instrumental in subsequent mysid domestication. These results are consistent with domestication via the commensal pathway, by which many common examples of animal domestication are hypothesized to have evolved.
UHPLC-Q-TOF analysis of pyrrolizidine alkaloids in North-Macedonian honey
Creators: name: Cvetanoska, Marinela
name: Pocrnić, Marijana
name: Stefova, Marina
name: Galić, Nives
name: Stanoeva, Jasmina Petreska
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Honey contaminated with pyrrolizidine alkaloids (PAs) could pose a risk for human consumption, being a widely consumed food product. A fast and simple LC/MS method for the analysis of pyrrolizidine alkaloids in honey was optimised to collect occurrence data. The extraction efficiency was evaluated by a systematic study of multiple solvent mixtures and clean-up procedures. The best results for PA extraction were obtained using a formic acid/methanol mixture with subsequent clean-up by the QuEChERS method, resulting in a mean recovery range of 91.8–102%. The method validation showed satisfactory intra-day (RSD < 5.1%) and inter-day precision (RSD < 9.1%). The proposed method was applied to 14 samples. A total of six PAs and two N-oxides were detected, with levels between 89 and 8188 µg/kg. This assessment highlights the potential risk of intoxication and the need for further investigations regarding an effective quality system for manufacturers to control PAs in honey.
HRMS analysis of pesticides in vegetables from Shanghai and risk assessment
Creators: name: Si, Wenshuai
name: Huo, Kaixuan
name: Wu, Nan
name: Yang, Haifeng
name: Liu, Haiyan
name: Jin, Xiaofen
name: Chen, Lei
name: Huang, Zhiying
name: Wang, Shouying
name: Bai, Bing
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: A rapid analytical method for the simultaneous determination of 550 pesticide residues in vegetable samples was developed based on ultra-high performance liquid chromatography-tandem Q/Orbitrap high-resolution mass spectrometry (UPLC-Q/Orbitrap-HRMS). To investigate the risk of exposure to pesticide residues through vegetable consumption, 704 leafy vegetable samples from Shanghai were analysed for multiple residues using this method. A total of 54 pesticide residues were identified in these vegetable samples and 302 samples contained one or more pesticide residue. The levels of the detected pesticides did not pose a health risk in the long term and were acceptable according to the results of the chronic dietary risk assessment. Risk rankings displayed that most of the pesticides were low to medium risk. The findings of this study provide a reference for future pesticide monitoring programmes.
Syzeuctus kespius Ugalde & Gauld 2002
Creators: name: González-Moreno, Alejandra
name: Bordera, Santiago
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Syzeuctus
Syzeuctus kespius

description: Syzeuctus kespius Ugalde & Gauld 2002
 Distribution. Neotropical (Costa Rica).
 Habitat. Coastal dune scrubland, savannah, dry forest.
 Phenology. Appendix I (Fig. 5).
 Studied material. MEXICO. Yucatán State, Ria Lagartos Biosphere Reserve, Cuyo Station, Punta Meco: 28.VII–12.VIII.2008, 1 ♂; 28.VIII–10.IX.2008, 1 ♂; 27.VII–06.VIII.2009, 1 ♂. Sacbo: 12–28.VIII.2008, 1 ♂ (CCBA); 17.VI–01.VII.2008, 4 ♂♂; 01–14.VII.2008, 1 ♂; 12–28.VIII.2008, 1 ♂ (CEUA).
description: Published as part of González-Moreno, Alejandra & Bordera, Santiago, 2011, New records of Ichneumonidae (Hymenoptera: Ichneumonoidea) from Mexico, pp. 1-21 in Zootaxa 2879 (1) on page 4, DOI: 10.11646/zootaxa.2879.1.1, http://zenodo.org/record/5285972
A search for TeV gamma-ray emission from SNRs, pulsars and unidentified GeV sources in the Galactic plane in the longitude range between -2 deg and 85 deg
Creators: name: HEGRA-Collaboration
name: Aharonian, F. A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Using the HEGRA system of imaging atmospheric Cherenkov telescopes, one quarter of the Galactic plane (-2 deg < l < 85 deg) was surveyed for TeV gamma-ray emission from point sources and moderately extended sources (diameter <= 0.8 deg). The region covered includes 86 known pulsars (PSR), 63 known supernova remnants (SNR) and nine GeV sources, representing a significant fraction of the known populations. No evidence for emission of TeV gamma radiation was detected, and upper limits range from 0.15 Crab units up to several Crab units, depending on the observation time and zenith angles covered. The ensemble sums over selected SNR and pulsar subsamples and over the GeV-sources yield no indication for emission from these potential sources. The upper limit for the SNR population is at the level of 6.7% of the Crab flux and for the pulsar ensemble at the level of 3.6% of the Crab flux.
description: 10 pages, 5 figures, 4 tables, accepted for publication in A&A
Coherent states on spheres
Creators: name: Hall, Brian C.
name: Mitchell, Jeffrey J.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We describe a family of coherent states and an associated resolution of the identity for a quantum particle whose classical configuration space is the d-dimensional sphere S^d. The coherent states are labeled by points in the associated phase space T*(S^d). These coherent states are NOT of Perelomov type but rather are constructed as the eigenvectors of suitably defined annihilation operators. We describe as well the Segal-Bargmann representation for the system, the associated unitary Segal-Bargmann transform, and a natural inversion formula. Although many of these results are in principle special cases of the results of B. Hall and M. Stenzel, we give here a substantially different description based on ideas of T. Thiemann and of K. Kowalski and J. Rembielinski. All of these results can be generalized to a system whose configuration space is an arbitrary compact symmetric space. We focus on the sphere case in order to be able to carry out the calculations in a self-contained and explicit way.
description: Revised version. Submitted to J. Mathematical Physics
Explaining the MiniBooNE excess by a decaying sterile neutrino with mass in the 250 MeV range
Creators: name: Fischer, Oliver
name: Hernandez-Cabezudo, Alvaro
name: Schwetz, Thomas
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The MiniBooNE collaboration has reported an excess of $460.5\pm 95.8$ electron-like events ($4.8σ$). We propose an explanation of these events in terms of a sterile neutrino decaying into a photon and a light neutrino. The sterile neutrino has a mass around 250 MeV and it is produced from kaon decays in the proton beam target via mixing with the muon or the electron in the range $10^{-11} \lesssim |U_{\ell 4}|^2 \lesssim 10^{-7}$ ($\ell = e,μ$). The model can be tested by considering the time distribution of the events in MiniBooNE and by looking for single-photon events in running or upcoming neutrino experiments, in particular by the suite of liquid argon detectors in the short-baseline neutrino program at Fermilab.
description: 26 pages, 9 figures. New references, supernova bound and an appendix about the impact of the timing cut are added
Conformational plasticity of ligand-bound and ternary GPCR complexes studied by 19 F NMR of the β 1 -adrenergic receptor
Creators: name: Frei, J. Niclas
name: Broadhurst, Richard W.
name: Bostock, Mark J.
name: Solt, Andras
name: Jones, Andrew J. Y.
name: Gabriel, Florian
name: Tandale, Aditi
name: Shrestha, Binesh
name: Nietlispach, Daniel
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/45
/631/45/612/1237
/631/45/535/878/1263
/631/57
/631/535
/140/131
/101/6
article

description: Abstract: G-protein-coupled receptors (GPCRs) are allosteric signaling proteins that transmit an extracellular stimulus across the cell membrane. Using 19F NMR and site-specific labelling, we investigate the response of the cytoplasmic region of transmembrane helices 6 and 7 of the β1-adrenergic receptor to agonist stimulation and coupling to a Gs-protein-mimetic nanobody. Agonist binding shows the receptor in equilibrium between two inactive states and a pre-active form, increasingly populated with higher ligand efficacy. Nanobody coupling leads to a fully active ternary receptor complex present in amounts correlating directly with agonist efficacy, consistent with partial agonism. While for different agonists the helix 6 environment in the active-state ternary complexes resides in a well-defined conformation, showing little conformational mobility, the environment of the highly conserved NPxxY motif on helix 7 remains dynamic adopting diverse, agonist-specific conformations, implying a further role of this region in receptor function. An inactive nanobody-coupled ternary receptor form is also observed.
Optimal day-ahead orders using stochastic programming and noise-driven RNNs
Creators: name: Biel, Martin
Publisher: name: arXiv
Year: 2019
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: This paper presents a methodology for strategic day-ahead planning that uses a combination of deep learning and optimization. A noise-driven recurrent neural network structure is proposed for forecasting electricity prices and local inflow to water reservoirs. The resulting forecasters generate predictions with seasonal variation without relying on long input sequences. This forecasting method is employed in a stochastic program formulation of the day-ahead problem. This results in optimal order strategies for a price-taking hydropower producer participating in the Nordic day-ahead market. Using an open-source software framework for stochastic programming, the model is implemented and distributed over multiple cores. The model is then solved in parallel using a sampling-based algorithm. Tight confidence intervals around the stochastic solution are provided, which show that the gain from adopting a stochastic approach is statistically significant.
Fermi and Non-Fermi Liquid Behavior of Quantum Impurity Models: A Diagrammatic Pseudo-particle Approach
Creators: name: Kroha, J.
name: Wölfle, P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We review a systematic many-body method capable of describing Fermi liquid and Non-Fermi liquid behavior of quantum impurity models at low temperatures on the same footing. The crossover to the high temperature local moment regime is covered as well. The approach makes use of a pseudo-particle representation of the impurity Hilbert space in the limit of infinite Coulomb repulsion $U$ as well as for finite $U$. Approximations are derived from a generating Luttinger-Ward functional, in terms of renormalized perturbation theory in the hybridization $V$. Within a ``conserving T-matrix approximation'' (CTMA), including all two-particle vertex functions, an infinite series of leading infrared singular skeleton diagrams is included. The local constraint is strictly enforced. Applied to the SU(N) $\times$ SU(M) multichannel Anderson model the method allows to recover the Fermi liquid behavior of the single channel case, as well as the non-Fermi liquid behavior in the multi-channel case. The results are compared with the ``non-crossing approximation'' (NCA) and with data obtained by the numerical renormalization group and the Bethe ansatz. The generalization of the method to the case of finite on-site repulsion $U$ is presented in a systematical way and solved on the level of a generalized NCA, fully symmetric with respect to all virtual excitations of the model.
description: 24 pages, 15 figures. Dedicated to Erwin M\"uller-Hartmann on the occasion of his 60th birthday
ICP-OES analysis of total As and Cd in Columbian Oryza sativa L. rice
Creators: name: Salamanca, Ana María Calvo
name: Mogollon, Olga Lucia Mayorga
name: Chaali, Nesrine
name: Ariza-Nieto, Claudia
name: Beltran-Medina, José Isidro
name: Cuadros, Ronnal Esneyder Ortiz
name: Cruz, Erika Natalia Duran
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Arsenic (As) and cadmium (Cd) are considered toxic elements, even at trace levels. Their accurate quantification in crops can be complex at low levels and due to interference with other elements. The aim of this work was to develop and validate an analytical method for As and Cd quantification in rice stem and grains from the production systems “Irrigated Rice Ecosystems” (IRE) and “Rainfed Rice Ecosystems” (RRE) in Colombia. Mineralisation was carried out by acid digestion using an open system with a heating plate. Metal detection was performed by inductively coupled plasma optical emission spectrometry (ICP‐OES). Method adjustment, calibration, and validation were performed in accordance with AOAC standards, considering sensitivity, precision, accuracy, and selectivity parameters. The obtained method was applied to quantify levels in 259 rice stem and 443 grain samples from IRE and RRE.
Efficient training of energy-based models via spin-glass control
Creators: name: Pozas-Kerstjens, Alejandro
name: Muñoz-Gil, Gorka
name: Piñol, Eloy
name: García-March, Miguel Ángel
name: Acín, Antonio
name: Lewenstein, Maciej
name: Grzybowski, Przemysław R.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Machine Learning (cs.LG)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We introduce a new family of energy-based probabilistic graphical models for efficient unsupervised learning. Its definition is motivated by the control of the spin-glass properties of the Ising model described by the weights of Boltzmann machines. We use it to learn the Bars and Stripes dataset of various sizes and the MNIST dataset, and show how they quickly achieve the performance offered by standard methods for unsupervised learning. Our results indicate that the standard initialization of Boltzmann machines with random weights equivalent to spin-glass models is an unnecessary bottleneck in the process of training. Furthermore, this new family allows for very easy access to low-energy configurations, which points to new, efficient training algorithms. The simplest variant of such algorithms approximates the negative phase of the log-likelihood gradient with no Markov chain Monte Carlo sampling costs at all, and with an accuracy sufficient to achieve good learning and generalization.
description: 16 pages, 7+1 figures, RevTeX 4.1. Code is available at https://github.com/apozas/rapid/. v4: Updated to match published version
Statistical and Economic Evaluation of Time Series Models for Forecasting Arrivals at Call Centers
Creators: name: Bastianin, Andrea
name: Galeotti, Marzio
name: Manera, Matteo
name: Bastianin, Andrea
name: Galeotti, Marzio
name: Manera, Matteo
Publisher: name: Unknown
Year: 2017
Subjects: subject: Research Methods/ Statistical Methods
subject: ARIMA
subject: Call Center Arrivals
subject: Loss Function
subject: Seasonality
subject: Telecommunications Forecasting

description: Call centers' managers are interested in obtaining accurate forecasts of call arrivals because these are a key input in staffing and scheduling decisions. Therefore their ability to achieve an optimal balance between service quality and operating costs ultimately hinges on forecast accuracy. We present a strategy to model selection in call centers which is based on three pillars: (i) a flexible loss function; (ii) statistical evaluation of forecast accuracy; (iii) economic evaluation of forecast performance using money metrics. We implement fourteen time series models and seven forecast combination schemes on three series of call arrivals. We show that second moment modeling is important when forecasting call arrivals. From the point of view of a call center manager, our results indicate that outsourcing the development of a forecasting model is worth its cost, since the simple Seasonal Random Walk model is always outperformed by other, relatively more sophisticated, specifications.
Syzeuctus lurinus Ugalde & Gauld 2002
Creators: name: González-Moreno, Alejandra
name: Bordera, Santiago
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Syzeuctus
Syzeuctus lurinus

description: Syzeuctus lurinus Ugalde & Gauld 2002
 Distribution. Neotropical (Costa Rica).
 Habitat. Coastal dune scrubland, savannah, dry forest.
 Phenology. Appendix I (Fig. 6).
 Studied material. MEXICO. Yucatán State, Ria Lagartos Biosphere Reserve, Ría Lagartos Station, Post 024: 14–28.VII.2008, 1 ♀; 10–24. VI.2009, 1 ♀. Core II: 03–17. VI.2008, 1 ♀; 24.IX–08.X.2008, 1 ♀. Cuyo Station, Cemetery: 24. VI –08.VII.2009, 1 ♀; 27.VII–06.VIII.2009, 2 ♀. Punta Meco: 16. V –03. VI.2008, 1 ♂; 14– 28.VII.2008, 1 ♀; 28.VII–12.VIII.2008, 7 ♂♂; 12–28.VIII.2008, 1 ♂; 10–24.IX.2008, 1 ♀, 1 ♂; 10–26.XI.2008, 1 ♂; 26.XI-10.XII.2008, 1 ♂; 10–24. VI.2009, 1 ♂; 27.VII–06.VIII.2009, 1 ♂ (CCBA). Sacbo: 17. VI –01.VII.2008, 1 ♀; 01–14.VII.2008, 3 ♀; 14–28.VII.2008, 1 ♀; 28.VII–12.VIII.2008, 3 ♀; 24.IX–08.X.2008, 1 ♀; 24. VI – 08.VII.2009, 4 ♀; 08–22.VII.2009, 1 ♀; 27.VII–06.VIII.2009, 1 ♀. Tekal: 17. VI –01.VII.2008, 5 ♀; 01– 14.VII.2008, 1 ♀; 28.VII–12.VIII.2008, 2 ♀; 12–28.VIII.2008, 2 ♀; 08–22.VII.2009, 4 ♀, 1 ♂; 27.VII– 06.VIII.2009, 1 ♀ (CEUA).
description: Published as part of González-Moreno, Alejandra & Bordera, Santiago, 2011, New records of Ichneumonidae (Hymenoptera: Ichneumonoidea) from Mexico, pp. 1-21 in Zootaxa 2879 (1) on page 5, DOI: 10.11646/zootaxa.2879.1.1, http://zenodo.org/record/5285972
Gene and Cell-Based Therapies for Parkinson’s Disease: Where Are We?
Creators: name: Buttery, Philip C.
name: Barker, Roger A.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Review
Gene therapy
lentivirus
adeno-associated virus
growth factor
embryonic
pluripotent

description: Abstract: Parkinson’s disease (PD) is a neurodegenerative disorder that carries large health and socioeconomic burdens. Current therapies for PD are ultimately inadequate, both in terms of symptom control and in modification of disease progression. Deep brain stimulation and infusion therapies are the current mainstay for treatment of motor complications of advanced disease, but these have very significant drawbacks and offer no element of disease modification. In fact, there are currently no agents that are established to modify the course of the disease in clinical use for PD. Gene and cell therapies for PD are now being trialled in the clinic. These treatments are diverse and may have a range of niches in the management of PD. They hold great promise for improved treatment of symptoms as well as possibly slowing progression of the disease in the right patient group. Here, we review the current state of the art for these therapies and look to future strategies in this fast-moving field.
Bregman Itoh–Abe Methods for Sparse Optimisation
Creators: name: Benning, Martin
name: Riis, Erlend Skaldehaug
name: Schönlieb, Carola-Bibiane
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
Non-convex optimisation
Non-smooth optimisation
Bregman iteration
Inverse scale space
Geometric numerical integration
Discrete gradient methods
49M37
49Q15
65K10
90C26

description: Abstract: In this paper we propose optimisation methods for variational regularisation problems based on discretising the inverse scale space flow with discrete gradient methods. Inverse scale space flow generalises gradient flows by incorporating a generalised Bregman distance as the underlying metric. Its discrete-time counterparts, Bregman iterations and linearised Bregman iterations are popular regularisation schemes for inverse problems that incorporate a priori information without loss of contrast. Discrete gradient methods are tools from geometric numerical integration for preserving energy dissipation of dissipative differential systems. The resultant Bregman discrete gradient methods are unconditionally dissipative and achieve rapid convergence rates by exploiting structures of the problem such as sparsity. Building on previous work on discrete gradients for non-smooth, non-convex optimisation, we prove convergence guarantees for these methods in a Clarke subdifferential framework. Numerical results for convex and non-convex examples are presented.
Phase diagram of the random Heisenberg antiferromagnetic spin-1 chain
Creators: name: Saguia, A.
name: Boechat, B.
name: Continentino, M. A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We present a new perturbative real space renormalization group (RG) to study random quantum spin chains and other one-dimensional disordered quantum systems. The method overcomes problems of the original approach which fails for quantum random chains with spins larger than S=1/2. Since it works even for weak disorder we are able to obtain the zero temperature phase diagram of the random antiferromagnetic Heisenberg spin-1 chain as a function of disorder. We find a random singlet phase for strong disorder and as disorder decreases, the system shows a crossover from a Griffiths to a disordered Haldane phase.
description: 4 pages, 10 figures
Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Creators: name: Modvig, Ida M.
name: Andersen, Daniel B.
name: Grunddal, Kaare V.
name: Kuhre, Rune E.
name: Martinussen, Christoffer
name: Christiansen, Charlotte B.
name: Ørskov, Cathrine
name: Larraufie, Pierre
name: Kay, Richard G.
name: Reimann, Frank
name: Gribble, Fiona M.
name: Hartmann, Bolette
name: Bojsen-Møller, Kirstine N.
name: Madsbad, Sten
name: Wewer Albrechtsen, Nicolai J.
name: Holst, Jens J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/443/319
/692/163/2743
/631/45/776/198
/692/163/2743/137/773
/692/163/2743/393
/14/32
/82/51
/38/91
/82/58
/82/83
article

description: Abstract: Objectives: Gastrointestinal hormones contribute to the beneficial effects of Roux-en-Y gastric bypass surgery (RYGB) on glycemic control. Secretin is secreted from duodenal S cells in response to low luminal pH, but it is unknown whether its secretion is altered after RYGB and if secretin contributes to the postoperative improvement in glycemic control. We hypothesized that secretin secretion increases after RYGB as a result of the diversion of nutrients to more distal parts of the small intestine, and thereby affects islet hormone release. Methods: A specific secretin radioimmunoassay was developed, evaluated biochemically, and used to quantify plasma concentrations of secretin in 13 obese individuals before, 1 week after, and 3 months after RYGB. Distribution of secretin and its receptor was assessed by RNA sequencing, mass-spectrometry and in situ hybridization in human and rat tissues. Isolated, perfused rat intestine and pancreas were used to explore the molecular mechanism underlying glucose-induced secretin secretion and to study direct effects of secretin on glucagon, insulin, and somatostatin secretion. Secretin was administered alone or in combination with GLP-1 to non-sedated rats to evaluate effects on glucose regulation. Results: Plasma postprandial secretin was more than doubled in humans after RYGB (P < 0.001). The distal small intestine harbored secretin expressing cells in both rats and humans. Glucose increased the secretion of secretin in a sodium-glucose cotransporter dependent manner when administered to the distal part but not into the proximal part of the rat small intestine. Secretin stimulated somatostatin secretion (fold change: 1.59, P < 0.05) from the perfused rat pancreas but affected neither insulin (P = 0.2) nor glucagon (P = 0.97) secretion. When administered to rats in vivo, insulin secretion was attenuated and glucagon secretion increased (P = 0.04), while blood glucose peak time was delayed (from 15 to 45 min) and gastric emptying time prolonged (P = 0.004). Conclusions: Glucose-sensing secretin cells located in the distal part of the small intestine may contribute to increased plasma concentrations observed after RYGB. The metabolic role of the distal S cells warrants further studies.
MOESM1 of Cancer patterns and association with mortality and renal outcomes in non-dialysis dependent chronic kidney disease: a matched cohort study
Creators: name: Chinnadurai, Rajkumar
name: Flanagan, Emma
name: Jayson, Gordon
name: Kalra, Philip
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Figure S1. Cumulative incidence probability for death and renal replacement therapy (RRT) between the groups (cancer vs no cancer) in the matched sample. Figure S2. Kaplan-Meier curve for all-cause mortality in the matched sample (comparison between groups split based on date of cancer occurrence prior to recruitment). Figure S3. Kaplan-Meier curve for renal replacement therapy (RRT) free survival in the matched sample (comparison between groups split based on date of cancer occurrence prior to recruitment). Figure S4. Kaplan-Meier curve for all-cause mortality in the matched sample (comparison between groups split based on cancer sites with no cancer).
A 60 pc counter-rotating core in NGC 4621
Creators: name: Wernli, Fabien
name: Emsellem, Eric
name: Copin, Yannick
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present adaptive optics assisted OASIS integral field spectrography of the S0 galaxy NGC 4621. Two-dimensional stellar kinematical maps (mean velocity and dispersion) reveal the presence of a 60 pc diameter counter-rotating core (CRC), the smallest observed to date. The OASIS data also suggests that the kinematic center of the CRC is slightly offset from the center of the outer isophotes. This seems to be confirmed by archival HST/STIS data. We also present the HST/WFPC2 V-I colour map, which exhibits a central elongated red structure, also slightly off-centered in the same direction as the kinematic centre. We then construct an axisymmetric model of NGC 4621: the two-integral distribution function is derived using the Multi-Gaussian Expansion and the Hunter & Qian (1993) formalisms. Although the stellar velocities are reasonably fitted, including the region of the counter-rotating core, significant discrepancies between the model and the observations demonstrate the need for a more general model (e.g. a three-integral model).
description: 9 pages, 8 figures