cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the Density of Ranges of Generalized Divisor Functions with Restricted Domains
Creators: name: Defant, Colin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11B05, 11A25

description: We begin by defining functions $σ_{t,k}$, which are generalized divisor functions with restricted domains. For each positive integer $k$, we show that, for $r>1$, the range of $σ_{-r,k}$ is a subset of the interval $\displaystyle{\left[1,\frac{ζ(r)}{ζ((k+1)r)}\right)}$. After some work, we define constants $η_k$ which satisfy the following: If $k\in\mathbb{N}$ and $r>1$, then the range of the function $σ_{-r,k}$ is dense in $\displaystyle{\left[1,\frac{ζ(r)}{ζ((k+1)r)}\right)}$ if and only if $r\leqη_k$. We end with an open problem.
description: 16 pages, 0 figures
title: Dose reconstruction for pediatric cardiac catheterizations in the 1980s – an input to the epidemiological study HARMONIC
Creators: name: Olerud, Hilde
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Cardiac
subject: Paediatric
subject: Radiation physics
subject: Catheter arteriography
subject: Fluoroscopy
subject: Radiation safety
subject: Technical aspects
subject: Congenital

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The occurrence of children born with congenital heart defects (CHD) is about 1 %. Of these, 25% will need invasive or other potentially life-saving diagnosis or treatment [1]. The increasing long-term survival of these children have raised concerns...
Recent progress on the positive energy theorem
Creators: name: Zhang, Xiao
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We give a short review of recent progress on the positive energy theorem in general relativity, especially for spacetimes with nonzero cosmological constant.
description: 20 pages, contribution to Proceedings of the International Conference on Gravitation and Cosmology/The Fourth Galileo-Xu Guangqi Meeting, final version
title: Improving microvascular display using smaller and targeted display field-of-view combined with high-weight ASIR-V in abdominal CT angiography
Creators: name: Wang, Xu
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Vascular
subject: CT
subject: CT-Angiography
subject: Contrast agent-intravenous
subject: Blood

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: To explore the influence of using a smaller and targeted display field-of-view (DFOV) combined with high-weighted ASIR-V reconstruction in routine abdominal CT angiography (CTA) on the display of...
Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization: Psl and the innate immune response towards P. aeruginosa
Creators: name: Schlesinger, Larry S.
name: Azad, Abul K.
name: Byrd, Matthew S.
name: Wozniak, Daniel J.
name: Sergeant, Susan
name: Mishra, Meenu
name: Parsek, Matthew R.
name: McPhail, Linda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Pseudomonas aeruginosa causes chronic lung infections in the airways of cystic fibrosis (CF) patients. Psl is an extracellular polysaccharide expressed by non-mucoid P. aeruginosa strains, which are believed to be initial colonizers. We hypothesized that Psl protects P. aeruginosa from host defences within the CF lung prior to their conversion to the mucoid phenotype. We discovered that serum opsonization significantly increased the production of reactive oxygen species (ROS) by neutrophils exposed to a psl-deficient mutant, compared with wild-type (WT) and Psl overexpressing strains (Psl++). Psl-deficient P. aeruginosa were internalized and killed by neutrophils and macrophages more efficiently than WT and Psl++ variants. Deposition of complement components C3, C5 and C7 was significantly higher on psl-deficient strains compared with WT and Psl++ bacteria. In an in vivo pulmonary competition assay, there was a 4.5-fold fitness advantage for WT over psl-deficient P. aeruginosa. Together, these data show that Psl inhibits efficient opsonization, resulting in reduced neutrophil ROS production, and decreased killing by phagocytes. This provides a survival advantage in vivo. Since phagocytes are critical in early recognition and control of infection, therapies aimed at Psl could improve the quality of life for patients colonized with P. aeruginosa.
Neutron Star Mergers as the Origin of r-Process Elements in the Galactic Halo Based on the Sub-halo Clustering Scenario
Creators: name: Ishimaru, Yuhri
name: Wanajo, Shinya
name: Prantzos, Nikos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Binary mergers (NSMs) of double neutron star (and black hole-neutron star) systems are suggested to be major sites of r-process elements in the Galaxy by recent hydrodynamical and nucleosynthesis studies. It has been pointed out, however, that the estimated long lifetimes of neutron star binaries are in conflict with the presence of r-process-enhanced halo stars at metallicities as low as [Fe/H] ~ -3. To resolve this problem, we examine the role of NSMs in the early Galactic chemical evolution on the assumption that the Galactic halo was formed from merging sub-halos. We present simple models for the chemical evolution of sub-halos with total final stellar masses between 10^4 M_solar and 2 x 10^8 M_solar. Typical lifetimes of compact binaries are assumed to be 100 Myr (for 95% of their population) and 1 Myr (for 5%), according to recent binary population synthesis studies. The resulting metallcities of sub-halos and their ensemble are consistent with the observed mass-metallicity relation of dwarf galaxies in the Local Group, and the metallicity distribution of the Galactic halo, respectively. We find that the r-process abundance ratios [r/Fe] start increasing at [Fe/H] <= -3 if the star formation efficiencies are smaller for less massive sub-halos. In addition, the sub-solar [r/Fe] values (observed as [Ba/Fe] ~ -1.5 for [Fe/H] < -3) are explained by the contribution from the short-lived (~1 Myr) binaries. Our results indicate that NSMs may have a substantial contribution to the r-process element abundances throughout the Galactic history.
description: 5 pages, 2 figures, accepted for publication in ApJL
(401509) Edward Livingstone
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Vascular and non-vascular thoracic interventions
Creators: name: Filipović-Grčić, Luka
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Interventional non-vascular
subject: Interventional vascular
subject: Thorax
subject: CT
subject: Fluoroscopy
subject: Ultrasound
subject: Biopsy
subject: Embolisation
subject: Stents
subject: Aneurysms
subject: Arteriovenous malformations
subject: Varices

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: To provide a comprehensive overview of most common vascular and non-vascular thoracic intervention techniques To recognize specific indications and contraindications for thoracic...
Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread
Creators: name: Cheney, Richard E.
name: Li, Wei
name: Southwick, Frederick S.
name: Bishai, Ellen A.
name: Sidhu, Gurjit S.
name: Bohil, Aparna B.
name: Dhillon, Jess
name: Hartwig, John H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The intracellular pathogen Shigella flexneri forms membrane protrusions to spread from cell to cell. As protrusions form, myosin-X (Myo10) localizes to Shigella. Electron micrographs of immunogold-labelled Shigella-infected HeLa cells reveal that Myo10 concentrates at the bases and along the sides of bacteria within membrane protrusions. Time-lapse video microscopy shows that a full-length Myo10 GFP-construct cycles along the sides of Shigella within the membrane protrusions as these structures progressively lengthen. RNAi knock-down of Myo10 is associated with shorter protrusions with thicker stalks, and causes a >80% decrease in confluent cell plaque formation. Myo10 also concentrates in membrane protrusions formed by another intracellular bacteria, Listeria, and knock-down of Myo10 also impairs Listeria plaque formation. In Cos7 cells (contain low concentrations of Myo10), the expression of full-length Myo10 nearly doubles Shigella-induced protrusion length, and lengthening requires the head domain, as well as the tail-PH domain, but not the FERM domain. The GFP-Myo10-HMM domain localizes to the sides of Shigella within membrane protrusions and the GFP-Myo10-PH domain localizes to host cell membranes. We conclude that Myo10 generates the force to enhance bacterial-induced protrusions by binding its head region to actin filaments and its PH tail domain to the peripheral membrane.
title: Reporting radiographers in Norway -a missing link?
Creators: name: Berntsen, Astrid
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Management
subject: Professional issues
subject: Plain radiographic studies
subject: Education
subject: Quality assurance

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The purpose of the study is to describe the experience of reporting radiographers in Norway, how they work and cooperate in the imaging department, their competence, skills, and their new...
O'QITISH METODLARIGA ZAMONAVIY INNOVATSION TEXNOLOGIYALARNI QO'SHISH ORQALI TA'LIM SIFATINI YAXSHILASH.
Creators: name: Sattarova, Dilnoza
Publisher: name: Zenodo
Year: 2023

description: Ушбу мақолада таълим жараёнида замонавий коммуникацион технологиялардан фойдаланишнинг йўллари батафсил ёритиб берилган.
Parallelization Strategies for Spatial Agent-Based Models
Creators: name: Fachada, Nuno
name: Lopes, Vitor V.
name: Martins, Rui C.
name: Rosa, Agostinho C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences
subject: D.1.3; D.2.4; G.3; I.6.6

description: Agent-based modeling (ABM) is a bottom-up modeling approach, where each entity of the system being modeled is uniquely represented as an independent decision-making agent. Large scale emergent behavior in ABMs is population sensitive. As such, the number of agents in a simulation should be able to reflect the reality of the system being modeled, which can be in the order of millions or billions of individuals in certain domains. A natural solution to reach acceptable scalability in commodity multi-core processors consists of decomposing models such that each component can be independently processed by a different thread in a concurrent manner. In this paper we present a multithreaded Java implementation of the PPHPC ABM, with two goals in mind: 1) compare the performance of this implementation with an existing NetLogo implementation; and, 2) study how different parallelization strategies impact simulation performance on a shared memory architecture. Results show that: 1) model parallelization can yield considerable performance gains; 2) distinct parallelization strategies offer specific trade-offs in terms of performance and simulation reproducibility; and, 3) PPHPC is a valid reference model for comparing distinct implementations or parallelization strategies, from both performance and statistical accuracy perspectives.
description: The peer-reviewed version of this paper is published in the International Journal of Parallel Programming at http://dx.doi.org/10.1007/s10766-015-0399-9 . This version is typeset by the authors and differs only in pagination and typographical detail
Strukturwandel im Agrarsektor
Creators: name: Kirschke, Dieter
name: Odening, Martin
name: Häger, Astrid
name: Mußhoff, Oliver
Publisher: name: Humboldt-Universität zu Berlin, Landwirtschaftlich-Gärtnerische Fakultät
Year: 2007
Subjects: subject: Strukturwandel
subject: Agrarpolitik
subject: 630 Landwirtschaft, Veterinärmedizin

description: Das neue Bild des Strukturwandels im Agrarsektor wird geprägt durch eine Vielfalt wirtschaftlicher, politischer und institutioneller Veränderungsprozesse. Die gesellschaftlichen Ansprüche an den Agrarsektor haben sich gewandelt und sind vielfältiger und komplexer geworden, und der Paradigmenwechsel von einer eher protektionistischen Agrarpolitik zu einer stärker an Umwelt- und Qualitätszielen ausgerichteten Agrarpolitik hat erheblichen Einfluss auf strukturelle Entwicklungen. Zudem werden die strukturellen Veränderungsprozesse entscheidend geprägt durch neue Technologien und Internationalisierungs- und Globalisierungsprozesse. Von 2003 bis 2006 arbeitete an der Humboldt-Universität eine von der DFG geförderte Forschergruppe zu Fragen des Agrarstrukturwandels in Mitteleuropa. Der Beitrag stellt beispielhaft einige Ergebnisse der Forschungsarbeiten vor und skizziert künftige Arbeiten in dem Forschungsschwerpunkt. Am Beispiel des Agrarsektors geht es um ein neues und vertieftes Verständnis strukturellen Wandels in modernen Volkswirtschaften.
(401510) Isabella Speid
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Algen, Froscheier und Putzfimmel bei Fliegen
Creators: name: Nagel, Georg
name: Hegemann, Peter
name: Schwärzel, Martin
Publisher: name: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I
Year: 2007
Subjects: subject: Sekundäre Botenstoffe
subject: cAMP
subject: Signaltransduktion
subject: Methoden
subject: Verfahren
subject: 570 Biowissenschaften, Biologie

description: Zu den wichtigsten Signalmolekülen in lebenden Zellen gehört cAMP, das grundlegende Prozesse steuert. Wir haben kürzlich mithilfe eines Algenproteins eine neue Methode entwickelt, cAMP durch kurze Lichtblitze in tierischen Zellen und lebenden Tieren zu erzeugen. Bei Fliegen lassen sich damit Verhaltensänderungen an- und wieder abschalten. Die besonders hohe zeitliche Auflösung dieses neuen Lichtgesteuerten „Werkzeugs“ sollte es ermöglichen, die Rolle von cAMP bei komplexen biologischen Fragestellungen besser zu verstehen.
title: Out of the Ordinary: IgG4 Related Disease in Cardiothoracic Imaging
Creators: name: Jurkevičiūtė, Greta
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Thorax
subject: CT
subject: Education
subject: Inflammation

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: Review intrathoracic manifestations of the IgG4 related disease(IgG4-RD). Learn the radiologic appearances of pulmonary, airway, pleural, mediastinal and cardiovascular involvement of...
title: fMRI of human brain during visual stimulation, effect of acetylsalicylic acid
Creators: name: Ublinskiy, Maxim
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Neuroradiology brain
subject: MR-Functional imaging
subject: Chemistry
subject: Biological effects

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: In astrocytes, during neuroactivation under the action of PGH synthase, prostaglandins (derivatives of arachidonic acid (AA) which are capable of regulating local blood flow) are synthesized [1]. The only irreversible inhibitor of PGH synthase is...
title: Ruptured choledochal cyst presenting as loculated ascites due to abdominal tuberculosis
Creators: name: Gala, Foram
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Paediatric radiology
subject: Abdomen
subject: Paediatric
subject: CT
subject: MR-Cholangiography
subject: Clinical Cases

description: Clinical History: A 13-year-old female presented with fever, abdominal distension and pain for two weeks. Her external abdominopelvic ultrasound was suggestive of loculated intraperitoneal collections, raising the possibility of tuberculosis. Therefore, an ascitic fluid tap was performed afterwards confirming the presence of Mycobacterium tuberculosis. She was referred to our centre for further management. Serum direct bilirubin was raised and a CT scan (CECT) was ordered to look for the cause of obstructive jaundice.

description: 13 years, female
Enhanced phonological facilitation and traces of concurrent word form activation in speech production
Creators: name: Abdel Rahman, Rasha
name: Melinger, Alissa
Publisher: name: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II
Year: 2007
Subjects: subject: Enhanced phonological facilitation
subject: speech production
subject: experiments
subject: Cognitive Psychology
subject: 150 Psychologie

description: In the present study, we extended the classic picture–word interference paradigm by the presentation of multiple distractor words (Experiment 1) to reexamine whether the word forms of semantic alternatives receive activation in the course of object naming. Experiment 2 showed that phonological facilitation can be magnified by the presentation of multiple words that share overlapping initial and final segments with the target name. Experiments 3 and 4 tested for traces of nontarget phonological activation with multiple distractors, which enhances the chances of detecting such effects. These experiments revealed a consistent pattern of interference effects induced by words that were related to a semantic category member, consistent with theories assuming phonological activation of nontarget alternatives.
title: Accuracy of iodine quantification in Dual Energy CT for low iodine density renal cyst: a phantom study
Creators: name: Miyazaki, Yosuke
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Kidney
subject: CT
subject: Physics
subject: Artifacts
subject: Cysts

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Background Renal cyst pseudo-enhancement, an artificial increase of CT attenuation of renal cysts with increased iodine concentrations in renal parenchyma, leads to the mischaracterization of a benign non-enhancing cyst as an enhancing mass [1]....
Evaluation criteria for IFF projects and Evaluation Body
Creators: name: I.FAST WP4 Members
Publisher: name: Zenodo
Year: 2023

description: This deliverable reports the activity carried out by WP4 in relation to the organization and implementation of the Internal Innovation Fund. In particular, according to the I.FAST workplan, it is described the definition of the process, the appointment of the Evaluation Committee, the scoring of the projects, and the proposal to GB for award of 8 selected projects.
description: {"references": ["I.FAST Del4.1"]}
Commensal microbiota stimulate systemic neutrophil migration through induction of Serum amyloid A: Microbiota regulate systemic neutrophil function
Creators: name: Xiaolun, Sun
name: Grosser, Melinda R.
name: Flynn, Edward J.
name: Kanther, Michelle
name: Jobin, Christian
name: Rawls, John F.
name: Koo, Jaseol
name: Tomkovich, Sarah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Neutrophils serve critical roles in inflammatory responses to infection and injury, and mechanisms governing their activity represent attractive targets for controlling inflammation. The commensal microbiota is known to regulate the activity of neutrophils and other leucocytes in the intestine, but the systemic impact of the microbiota on neutrophils remains unknown. Here we utilized in vivo imaging in gnotobiotic zebrafish to reveal diverse effects of microbiota colonization on systemic neutrophil development and function. The presence of a microbiota resulted in increased neutrophil number and myeloperoxidase expression, and altered neutrophil localization and migratory behaviours. These effects of the microbiota on neutrophil homeostasis were accompanied by an increased recruitment of neutrophils to injury. Genetic analysis identified the microbiota-induced acute phase protein serum amyloid A (Saa) as a host factor mediating microbial stimulation of tissue-specific neutrophil migratory behaviours. In vitro studies revealed that zebrafish cells respond to Saa exposure by activating NF-κB, and that Saa-dependent neutrophil migration requires NF-κB-dependent gene expression. These results implicate the commensal microbiota as an important environmental factor regulating diverse aspects of systemic neutrophil development and function, and reveal a critical role for a Saa-NF-κB signalling axis in mediating neutrophil migratory responses.
Semantic priming in the name retrievalof objects and famous faces
Creators: name: Damian, Markus F.
name: Abdel Rahman, Rasha
Publisher: name: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II
Year: 2003
Subjects: subject: 150 Psychologie

description: Researchers interested in face processing have recently debated whether access to the name of a known person occurs in parallel with retrieval of semantic-biographical codes, rather than in a sequential fashion. Recently, Schweinberger, Burton, and Kelly (2001) took a failure to obtain a semantic context effect in a manual syllable judgment task on names of famous faces as support for this position. In two experiments, we compared the effects of visually presented categorically related prime words with either objects (e.g. prime: animal; target: dog) or faces of celebrities (e.g. prime: actor; target: Bruce Willis) as targets. Targets were either manually categorized with regard to the number of syllables (as in Schweinberger et al.), or they were overtly named. For neither objects nor faces was semantic priming obtained in syllable decisions; crucially, however, priming was obtained when objects and faces were overtly named. These results suggest that both face and object naming are susceptible to semantic context effects.
Elevated Intracellular Calcium Stimulates NHE3 Activity by an IKEPP (NHERF4) Dependent Mechanism
Creators: name: Kovbasnjuk, Olga
name: Cha, Boyoung
name: Thelin, William R.
name: Li, Xuhang
name: Zachos, Nicholas C.
name: Hodson, Caleb
name: Donowitz, Mark
name: Milgram, Sharon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The ileal brush border (BB) contains four evolutionarily related multi-PDZ domain proteins including NHERF1, NHERF2, PDZK1 (NHERF3) and IKEPP (NHERF4). Why multiple related PDZ proteins are in a similar location in the same cell is unknown. However, some specificity in regulation of NHE3 activity has been identified. For example, elevated intracellular Ca2+ ([Ca2+]i) inhibition of NHE3 is reconstituted by NHERF2 but not NHERF1, and involves the formation of large NHE3 complexes. To further evaluate the specificity of the NHERF family in calcium regulation of NHE3 activity, the current study determined whether the four PDZ domain containing protein IKEPP reconstitutes elevated [Ca2+]i regulation of NHE3. In vitro, IKEPP bound to the F2 region (aa 590-667) of NHE3 in overlay assays, which is the same region where NHERF1 and NHERF2 bind. PS120 cells lack endogenous NHE3 and IKEPP. Treatment of PS120/NHE3/IKEPP cells (stably transfected with NHE3 and IKEPP) with the Ca2+ ionophore, 4-Br-{"type":"entrez-nucleotide","attrs":{"text":"A23187","term_id":"833253","term_text":"A23187"}}A23187 (0.5μM), stimulated NHE3 Vmax activity by ∼40%. This was associated with an increase in plasma membrane expression of NHE3 by a similar amount. NHE3 activity and surface expression were unaffected by {"type":"entrez-nucleotide","attrs":{"text":"A23187","term_id":"833253","term_text":"A23187"}}A23187 in PS120/NHE3 cells lacking IKEPP. Based on sucrose density gradient centrifugation, IKEPP was also shown to exist in large complexes, some of which overlap in size with NHE3, and the size of both NHE3 and IKEPP complexes decreased in parallel after [Ca2+]i elevation. FRET experiments on fixed cells demonstrated that IKEPP and NHE3 directly associated at an intracellular site. Elevating [Ca2+]i decreased this intracellular NHE3 and IKEPP association. In summary: (1) In the presence of IKEPP, elevated [Ca2+]i stimulates NHE3 activity. This was associated with increased expression of NHE3 in the plasma membrane as well as a shift to smaller sizes of NHE3 and IKEPP containing complexes. (2) IKEPP directly binds NHE3 at its F2 C-terminal domain and directly associates with NHE3 in vivo (FRET). (3) Elevated [Ca2+]i decreased the association of IKEPP and NHE3 in an intracellular compartment. Based on which NHERF family member is expressed in PS120 cells, elevated [Ca2+]i stimulates (IKEPP), inhibits (NHERF2) or does not affect (NHERF1) NHE3 activity. This demonstrates that regulation of NHE3 depends on the nature of the NHERF family member associating with NHE3 and the accompanying NHE3 complexes.
JayaDB Whitepaper: A Unifying DBMS with Automatic Object Inference, Chainable Queries and Instance Expressions
Creators: name: Benanav, Dan
Publisher: name: Zenodo
Year: 2020
Subjects: Object-Relational Impedance Mismatch
NoSQL
Relational Database
Graph Database
Document Store
Object-Relational Mapping
ORM
Binary Relational Model

description: JayaDB, is an ACID compliant unifying DBMS based on a remarkable discovery in database theory. It solves the 40+ years problem of object-relational impedance mismatch in a surprising way. It subsumes relational, object-oriented, graph and document store DBMSs, yet is much easier to use than any other system. The benefits of JayaDB is significant. For example, the time and cost of development can be reduced by factors of 20 to 50. Furthermore, performance at all levels is enhanced without the need for any performance tuning. JayaDB is a no-brainer choice, rendering other DBMSs obsolete. Remarkably, JayaDB automatically generates object structures directly from queries. There are no ORM mappings required and only one high level model is required.
(401505) Betty Clarke
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Biodiversity path Velké Hostěrádky, 2024
Creators: name: Ekofarma PROBIO
name: Czech University of Life Sciences Prague
name: Czech Organics
Publisher: name: Zenodo
Year: 2024

description: The biodiversity path created in 2024 at Ekofarma PROBIO spans 7 km around the farm and includes six educational boards, offering visitors an immersive experience in learning about local ecology, organic farming, and regional biodiversity efforts.

Located in the South Moravian village of Velké Hostěrádky, this project is part of the larger H2020 FRAMEwork initiative, aimed at fostering voluntary collaboration between local farmers. Led by Martin Hutař, a pioneer in organic farming, the initiative not only seeks to enhance biodiversity in the area but also aims to boost the economic prosperity of its members and raise awareness of the region’s agricultural products.

As visitors walk along the path, they will gain insight into the significance of the local landscape, organic farming practices, and the collective efforts of the eight farmers involved, who manage organically around 2,000 hectares of land, including arable fields, grasslands, vineyards, and horticulture. Each educational board highlights a different aspect of the local ecosystem and the positive impact of organic farming, making this path a unique blend of education and nature.
Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress
Creators: name: Chhipa, Rishi Raj
name: Mohler, James L.
name: Wu, Yue
name: Ip, Clement
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Androgen-independent prostate cancer usually develops as a relapse following androgen ablation therapy. Removing androgen systemically causes vascular degeneration and nutrient depletion of the prostate tumor tissue. The fact that the malignancy later evolves to androgen-independence suggests that some cancer cells are able to survive the challenge of energy/nutrient deprivation. AMP-activated protein kinase (AMPK) is an important manager of energy stress. The present study was designed to investigate the role of AMPK in contributing to the survival of the androgen-independent phenotype. Most of the experiments were carried out in the androgen-dependent LNCaP cells and the androgen-independent C4-2 cells. These two cell lines have the same genetic background, since the C4-2 line is derived from the LNCaP line. Glucose deprivation (GD) was instituted to model energy stress encountered by these cells. The key findings are as follows. First, the activation of AMPK by GD was much stronger in C4-2 cells than in LNCaP cells, and the robustness of AMPK activation was correlated favorably with cell viability. Second, the response of AMPK was specific to energy deficiency rather than to amino acid deficiency. The activation of AMPK by GD was functional, as demonstrated by appropriate phosphorylation changes of mTOR and mTOR downstream substrates. Third, blocking AMPK activation by chemical inhibitor or dominant negative AMPK led to increased apoptotic cell death. The observation that similar results were found in other androgen-independent prostate cancer cell lines, including CW22Rv1 abd VCaP, provided further assurance that AMPK is a facilitator on the road to androgen-independence of prostate cancer cells.
title: Intravenous pyogenic granuloma in a 12-years-old patient
Creators: name: Pizzicato, Paolo
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Paediatric radiology
subject: Abdomen
subject: Paediatric
subject: Veins / Vena cava
subject: CT
subject: MR
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Clinical Cases

description: Clinical History: Previously healthy 12-year-old patient came to our attention for abdominal pain localized in the right upper quadrant of the abdomen. The remaining clinical examination and laboratory tests were within the normal limits, except for mild eosinophilia; furthermore, there were no alteration in hepatic, renal and coagulation function markers. 

description: 12 years, male
(401506) Ian Spencer Haughton-Brown
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Kalman Filter Tracking on Parallel Architectures
Creators: name: Cerati, Giuseppe
name: Elmer, Peter
name: Lantz, Steven
name: McDermott, Kevin
name: Riley, Dan
name: Tadel, Matevž
name: Wittich, Peter
name: Würthwein, Frank
name: Yagil, Avi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Power density constraints are limiting the performance improvements of modern CPUs. To address this we have seen the introduction of lower-power, multi-core processors, but the future will be even more exciting. In order to stay within the power density limits but still obtain Moore's Law performance/price gains, it will be necessary to parallelize algorithms to exploit larger numbers of lightweight cores and specialized functions like large vector units. Example technologies today include Intel's Xeon Phi and GPGPUs. Track finding and fitting is one of the most computationally challenging problems for event reconstruction in particle physics. At the High Luminosity LHC, for example, this will be by far the dominant problem. The need for greater parallelism has driven investigations of very different track finding techniques including Cellular Automata or returning to Hough Transform. The most common track finding techniques in use today are however those based on the Kalman Filter. Significant experience has been accumulated with these techniques on real tracking detector systems, both in the trigger and offline. They are known to provide high physics performance, are robust and are exactly those being used today for the design of the tracking system for HL-LHC. Our previous investigations showed that, using optimized data structures, track fitting with Kalman Filter can achieve large speedup both with Intel Xeon and Xeon Phi. We report here our further progress towards an end-to-end track reconstruction algorithm fully exploiting vectorization and parallelization techniques in a realistic simulation setup.
Additional file 1 of A multicentric, single arm, open-label, phase I/II study evaluating PSMA targeted radionuclide therapy in adult patients with metastatic clear cell renal cancer (PRadR)
Creators: name: Kryza, David
name: Vinceneux, Armelle
name: Bidaux, Anne-Sophie
name: Garin, Gwenaelle
name: Tatu, Delphine
name: Cropet, Claire
name: Badel, Jean-Noël
name: Perol, David
name: Giraudet, Anne-Laure
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1: PRadR study flow-chart
A Conceptual Framework for Conversational APIs
Creators: name: Bastos, João Antonio D. M.
name: Mello, Rafael Maiani De
name: Garcia, Alessandro Fabricio
Publisher: name: Zenodo
Year: 2020
Subjects: API Conversacional
Framework Conceitual
Engenharia Semiótica

description: Application programming interfaces (APIs) are everyday tools for any programmer. During its usage, an API mediates the communication process between designers and users. This mediation may be implemented in three different ways: the source code, the documentation, and the API behavior. According to the resources used, an API may reach higher or lower levels of conversation with its users. In this paper, we propose a conceptual framework for the definition and classification of conversational APIs. A conversational API is one capable of communicating its internal logic of operation and how to be properly used. Through the proposed framework, we introduce how to classify an API according to its level of conversation. Besides, we use our framework for evaluating three common Java APIs for managing date/time. Our experience indicates that the proposed conceptual framework may be useful for supporting designers in implementing their API interfaces accordingly to the proper needs of communication required by their different types of users.
title: Artificial intelligence for the diagnosis of lymph node metastases in patients with Head and Neck cancer: A systematic review
Creators: name: Ammirabile, Angela
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Head and neck
subject: Oncology
subject: CT
subject: MR
subject: Ultrasound
subject: Computer Applications-Detection, diagnosis
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Lymph Node (LN) status is one of the most important predictors of poor prognosis in head and neck cancers (H&N), but an accurate preoperative estimation of metastatic LNs remains difficult. [1] Non-invasive imaging – ultrasound (US), computed...
Semantic context effects in language production
Creators: name: Abdel Rahman, Rasha
name: Melinger, Alissa
Publisher: name: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II
Year: 2009
Subjects: subject: speech production
subject: lexical selection
subject: semantic context effects
subject: 000 Allgemeines, Wissenschaft

description: The investigation of semantic context effects has served as a valuable tool in investigating mechanisms of language production. Classic semantic interference effects have provided influential support for and interest in a competitive lexical selection mechanism. However, recent interest in semantic facilitation effects has stimulated a discussion on whether context effects reflect competition during lexical selection. In this review we propose a framework of lexical selection by competition that is sensitive to the activation of lexical cohorts. We outline our proposal and then present a selective review of the empirical evidence, much of which has been central to the development of alternative non-competitive models. We suggest that by adopting the assumptions of our proposal we can parsimoniously account for a majority of the discussed semantic facilitation and interference effects.
Test of the gravitational redshift with stable clocks in eccentric orbits: application to Galileo satellites 5 and 6
Creators: name: Delva, P.
name: Hees, A.
name: Bertone, S.
name: Richard, E.
name: Wolf, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Einstein Equivalence Principle (EEP) is one of the foundations of the theory of General Relativity and several alternative theories of gravitation predict violations of the EEP. Experimental constraints on this fundamental principle of nature are therefore of paramount importance. The EEP can be split in three sub-principles: the Universality of Free Fall (UFF), the Local Lorentz Invariance (LLI) and the Local Position Invariance (LPI). In this paper we propose to use stable clocks in eccentric orbits to perform a test of the gravitational redshift, a consequence of the LPI. The best test to date was performed with the Gravity Probe A (GP-A) experiment in 1976 with an uncertainty of $1.4\times10^{-4}$. Our proposal considers the opportunity of using Galileo satellites 5 and 6 to improve on the GP-A test uncertainty. We show that considering realistic noise and systematic effects, and thanks to a highly eccentric orbit, it is possible to improve on the GP-A limit to an uncertainty around $(3-4)\times 10^{-5}$ after one year of integration of Galileo 5 and 6 data.
description: 13 pages, 5 figures, accepted in Classical and Quantum Gravity as a Fast Track Communication
title: Skeletal manifestations of early congenital syphilis
Creators: name: Kuzma, Andressa
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Paediatric radiology
subject: Extremities
subject: Musculoskeletal bone
subject: Conventional radiography
subject: Clinical Cases

description: Clinical History: A term newborn with positive maternal screening for syphilis was treated with benzylpenicillin due to a serum VDRL (Venereal disease research laboratory) titer of 1:16 and cerebrospinal fluid VDRL titer of 1:64. At 28 days of age, she was hospitalised due to jaundice, and further imaging was obtained.

description: 28 days, female
(401507) Alexander Hamilton
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Generative Breast Shape 3D Model for Digital Breast Tomosynthesis
Creators: name: Pinto, Marta
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Breast
subject: Radiation physics
subject: Mammography
subject: Computer Applications-3D
subject: Physics
subject: Cancer

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Prior knowledge of the three-dimensional (3D) shape of the compressed breast can be very useful when developing image processing algorithms for digital mammography (DM) and digital breast tomosynthesis (DBT). Since both techniques involve breast...
Lens galaxies in the Illustris simulation: power-law models and the bias of the Hubble constant from time-delays
Creators: name: Xu, Dandan
name: Sluse, Dominique
name: Schneider, Peter
name: Springel, Volker
name: Vogelsberger, Mark
name: Nelson, Dylan
name: Hernquist, Lars
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A power-law density model, i.e., $ρ(r) \propto r^{-γ'}$ has been commonly employed in strong gravitational lensing studies, including the so-called time-delay technique used to infer the Hubble constant $H_0$. However, since the radial scale at which strong lensing features are formed corresponds to the transition from the dominance of baryonic matter to dark matter, there is no known reason why galaxies should follow a power law in density. The assumption of a power law artificially breaks the mass-sheet degeneracy, a well-known invariance transformation in gravitational lensing which affects the product of Hubble constant and time delay and can therefore cause a bias in the determination of $H_0$ from the time-delay technique. In this paper, we use the Illustris hydrodynamical simulations to estimate the amplitude of this bias, and to understand how it is related to observational properties of galaxies. Investigating a large sample of Illustris galaxies that have velocity dispersion $σ_{SIE}$>160 km/s at redshifts below $z=1$, we find that the bias on $H_0$ introduced by the power-law assumption can reach 20%-50%, with a scatter of $10\%-30\%$ (rms). However, we find that by selecting galaxies with an inferred power-law model slope close to isothermal, it is possible to reduce the bias on $H_0$ to <5%, and the scatter to <10%. This could potentially be used to form less biased statistical samples for $H_0$ measurements in the upcoming large survey era.
description: 18 pages, 15 figures, 2 tables. Monthly Notices of the Royal Astronomical Society, Volume 456, Issue 1, p.739-755
title: Langerhans Cell Histiocytosis: A case of predominant pulmonary presentation of multisystem disorder in an adolescent
Creators: name: Sarpangal, Madhura
Publisher: name: EURORAD
Year: 2023
Subjects: subject: Paediatric radiology
subject: Lung
subject: CT
subject: Clinical Cases

description: Clinical History: A 15-year-old boy presented with recent onset of breathlessness, weight loss, and tiredness for two months and a crusting erythematous scalp rash for six months. The investigations revealed neutrophilia, raised C-reactive protein (CRP), and Alanine Aminotransferase (ALT). The blood urea and electrolytes, thyroid function tests, anti-nuclear antibodies, and clotting studies were normal

description: 15 years, male
Dismissing lexical competition does not make speaking any easier
Creators: name: Abdel Rahman, Rasha
name: Melinger, Alissa
Publisher: name: Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II
Year: 2009
Subjects: subject: Lexical cohort activation
subject: Competition
subject: Semantic interference effect
subject: Speech production
subject: 150 Psychologie

description: The swinging lexical network proposal (Abdel Rahman & Melinger, 2009a this issue) incorporates three assumptions that are independently motivated and pre-existing in the literature. We claim that the combination of these three assumptions provides an account for a wide range of facilitation and interference observations. In their comment, Mahon and Caramazza question the success of our proposal by challenging the individual assumptions at its core. However, most of their criticisms are built on misconstruals of our proposal. Here, we revisit their points and clarify our position with regard to their specific concerns.We maintain that competition models do not necessitate an over-complication of lexical selection but rather provide an elegant and consistent mechanism to capture many empirical observations.
title: Imaging Review of Posterior Shoulder Instability: A Radiological Challenge
Creators: name: García Barón, Carlota
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Extremities
subject: MR-Angiography
subject: Diagnostic procedure
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References
description: Learning objectives: The shoulder is the most unstable joint within the musculoskeletal system, due to the range of motion allowed by the limited coverage of the humeral head by the glenoid. Glenohumeral instability is defined as the appearance of symptoms secondary to...