cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
Creators: name: Braig, David
name: Nero, Tracy L.
name: Koch, Hans-Georg
name: Kaiser, Benedict
name: Wang, Xiaowei
name: Thiele, Jan R.
name: Morton, Craig J.
name: Zeller, Johannes
name: Kiefer, Jurij
name: Potempa, Lawrence A.
name: Mellett, Natalie A.
name: Miles, Luke A.
name: Du, Xiao-Jun
name: Meikle, Peter J.
name: Huber-Lang, Markus
name: Stark, G. Björn
name: Parker, Michael W.
name: Peter, Karlheinz
name: Eisenhardt, Steffen U.
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: artificial phosphatidylcholine bilayers
subject: amyloid p component
subject: directed mutagenesis
subject: human pentraxins
subject: apoptotic cells
subject: globular head
subject: complement
subject: DDC 610 / Medicine & health
subject: C-reactive protein
subject: Endothelial cells
subject: Myocardial infarction
subject: Serum amyloid P-component
subject: Complement system proteins
subject: C-reaktives Protein
subject: Endothelzelle
subject: Herzinfarkt
subject: Komplement

description: C-reactive protein (CRP) concentrations rise in response to tissue injury or infection. Circulating pentameric CRP (pCRP) localizes to damaged tissue where it leads to complement activation and further tissue damage. In-depth knowledge of the pCRP activation mechanism is essential to develop therapeutic strategies to minimize tissue injury. Here we demonstrate that pCRP by binding to cell-derived microvesicles undergoes a structural change without disrupting the pentameric symmetry (pCRP*). pCRP* constitutes the major CRP species in human-inflamed tissue and allows binding of complement factor 1q (C1q) and activation of the classical complement pathway. pCRP*–microvesicle complexes lead to enhanced recruitment of leukocytes to inflamed tissue. A small-molecule inhibitor of pCRP (1,6-bis(phosphocholine)-hexane), which blocks the pCRP–microvesicle interactions, abrogates these proinflammatory effects. Reducing inflammation-mediated tissue injury by therapeutic inhibition might improve the outcome of myocardial infarction, stroke and other inflammatory conditions.
The DEEP2 galaxy redshift survey: Evolution of the colour-density relation at 0.4 z 1.35
Creators: name: Cooper, Michael C.
name: Newman, Jeffrey A.
name: Coil, Alison L.
name: Croton, Darren
name: Gerke, Brian F.
name: Yan, Renbin
name: Davis, Marc
name: Faber, S. M.
name: Guhathakurta, Puragra
name: Koo, David C.
name: Weiner, Benjamin J.
name: Willmer, Christopher N.A.
Publisher: name: Swinburne
Year: 2024

description: Using a sample of 19 464 galaxies drawn from the DEEP2 Galaxy Redshift Survey, we study the relationship between galaxy colour and environment at 0.4 < z < 1.35 . We find that the fraction of galaxies on the red sequence depends strongly on local environment out to z > 1 , being larger in regions of greater galaxy density. At all epochs probed, we also find a small population of red, morphologically early-type galaxies residing in regions of low measured overdensity. The observed correlations between the red fraction and local overdensity are highly significant, with the trend at z > 1 detected at a greater than 5σ level. Over the entire redshift regime studied, we find that the colour–density relation evolves continuously, with red galaxies more strongly favouring overdense regions at low z relative to their red-sequence counterparts at high redshift. At z≳ 1.3 , the red fraction only weakly correlates with overdensity, implying that any colour dependence to the clustering of ∼L* galaxies at that epoch must be small. Our findings add weight to existing evidence that the build-up of galaxies on the red sequence has occurred preferentially in overdense environments (i.e. galaxy groups) at z≲ 1.5 . Furthermore, we identify the epoch (z∼ 2) at which typical ∼L* galaxies began quenching and moved on to the red sequence in significant number. The strength of the observed evolutionary trends at 0 < z < 1.35 suggests that the correlations observed locally, such as the morphology–density and colour–density relations, are the result of environment-driven mechanisms (i.e. 'nurture') and do not appear to have been imprinted (by 'nature') upon the galaxy population during their epoch of formation.
Supplementary document for Efficient frequency conversion based on resonant four-wave mixing - 5010829.pdf
Creators: name: Chen, Yong-Fan
name: Cheng, Chin-Yao
name: Liu, Zi-Yu
name: Hu, Pi-Sheng
name: Wang, Tsai-Ni
name: Chien, Chung-Yu
name: Lin, Jia-Kang
name: Juo, Jz-Yuan
name: Shiu, Jiun-Shiuan
name: Yu, Ite
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental 1
Supplementary document for Efficient frequency conversion based on resonant four-wave mixing - 5010829.pdf
Creators: name: Chen, Yong-Fan
name: Cheng, Chin-Yao
name: Liu, Zi-Yu
name: Hu, Pi-Sheng
name: Wang, Tsai-Ni
name: Chien, Chung-Yu
name: Lin, Jia-Kang
name: Juo, Jz-Yuan
name: Shiu, Jiun-Shiuan
name: Yu, Ite
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplemental 1
Disentangling how climate change can affect an aquatic food web by combining multiple experimental approaches
Creators: name: Amundrud, Sarah L.
name: Srivastava, Diane S., 1969-
Publisher: name: The University of British Columbia
Year: 2025

description: Predicting the biological effects of climate change presents major challenges due to the interplay of potential biotic and abiotic mechanisms. Climate change can create unexpected outcomes by altering species interactions, and uncertainty over the ability of species to develop in situ tolerance or track environmental change further hampers meaningful predictions. As multiple climatic variables shift in concert, their potential interactions further complicate ecosystem responses. Despite awareness of these complexities, we still lack controlled experiments that manipulate multiple climatic stressors, species interactions, and prior exposure of species to future climatic conditions. Particularly studies that address how changes in water availability interact with other climatic stressors to affect aquatic ecosystems are still rare. Using aquatic insect communities of Neotropical tank bromeliads, we combined controlled manipulations of drought length and species interactions with a space-for-time transplant (lower elevations represent future climate) and a common garden approach. Manipulating drought length and experiment elevation revealed that adverse effects of drought were amplified at the warmer location, highlighting the potential of climatic stressors to synergistically affect communities. Manipulating the presence of omnivorous tipulid larvae showed that negative interactions from tipulids, presumably from predation, arose under drought, and were stronger at the warmer location, stressing the importance of species interactions in mediating community responses to climate change. The common garden treatments revealed that prior community exposure to potential future climatic conditions did not affect the outcome. In this powerful experiment, we demonstrated how complexities arise from the interplay of biotic and abiotic mechanisms of climate change. We stress that single species can steer ecological outcomes, and suggest that focusing on such disproportionately influential species may improve attempts at making meaningful predictions of climate change impacts on food webs.
The DEEP2 galaxy redshift survey: The evolution of the blue fraction in groups and the field
Creators: name: Gerke, Brian F.
name: Newman, Jeffrey A.
name: Faber, S. M.
name: Cooper, Michael C.
name: Croton, Darren
name: Davis, Marc
name: Willmer, Christopher N.A.
name: Yan, Renbin
name: Coil, Alison L.
name: Guhathakurta, Puragra
name: Koo, David C.
name: Weiner, Benjamin J.
Publisher: name: Swinburne
Year: 2024

description: We explore the behaviour of the blue galaxy fraction over the redshift range 0.75 ≤z≤ 1.3 in the DEEP2 Survey, both for field galaxies and for galaxies in groups. The primary aim is to determine the role that groups play in driving the evolution of galaxy colour at high z. In pursuing this aim, it is essential to define a galaxy sample that does not suffer from redshift-dependent selection effects in colour-magnitude space. We develop four such samples for this study: at all redshifts considered, each one is complete in colour-magnitude space, and the selection also accounts for evolution in the galaxy luminosity function. These samples will also be useful for future evolutionary studies in DEEP2. The colour segregation observed between local group and field samples is already in place at z ∼ 1: DEEP2 groups have a significantly lower blue fraction than the field. At fixed z, there is also a correlation between blue fraction and galaxy magnitude, such that brighter galaxies are more likely to be red, both in groups and in the field. In addition, there is a negative correlation between blue fraction and group richness. In terms of evolution, the blue fraction in groups and the field remains roughly constant from z = 0.75 to 1, but beyond this redshift the blue fraction in groups rises rapidly with z, and the group and field blue fractions become indistinguishable at z ∼ 1.3. Careful tests indicate that this effect does not arise from known systematic or selection effects. To further ensure the robustness of this result, we build on previous mock DEEP2 catalogues to develop mock catalogues that reproduce the colour-overdensity relation observed in DEEP2 and use these to test our methods. The convergence between the group and field blue fractions at z ∼ 1.3 implies that DEEP2 galaxy groups only became efficient at quenching star formation at z ∼ 2; this result is broadly consistent with other recent observations and with current models of galaxy evolution and hierarchical structure growth.
Supplementary document for Raman pure quartic solitons in Kerr microresonators - 5012067.pdf
Creators: name: Liu, Kewei
name: Yao, Shunyu
name: Yang, Changxi
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: This supplemental document contains the details of the numerical simulation model and analytical derivation in the stability analysis part
Factors associated with willingness to wear an electronic overdose detection device
Creators: name: Ahamad, Keith
name: Dong, Huiru
name: Johnson, Cheyenne
name: Hyashi, Kanna
name: DeBeck, Kora
name: Milloy, M-J
name: Wood, Evan
Publisher: name: BioMed Central
Year: 2019

description: Background: North America is in the midst of an opioid overdose epidemic. Although take-home naloxone and other measures have been an effective strategy to reduce overdoses, many events are unwitnessed and mortality remains high amongst those using drugs alone. While wearable devices that can detect and alert others of an overdose are being developed, willingness of people who use drugs to wear such a device has not been described. Methods: Drug using persons enrolled in a community-recruited cohort in Vancouver, Canada, were asked whether or not they would be willing to wear a device against their skin that would alert others in the event of an overdose. Logistic regression was used to identify factors independently associated with willingness to wear such a device. Results: Among the 1061 participants surveyed between December 2017 and May 2018, 576 (54.3%) were willing to wear an overdose detection device. Factors independently associated with willingness included ever having overdosed (adjusted odds ratio [AOR] = 1.39, 95% confidence interval [CI] 1.06–1.83), current methadone treatment (AOR = 1.86, 95% CI 1.45–2.40), female gender AOR = 1.41, 95% CI 1.09–1.84) and a history of chronic pain (AOR = 1.53, 95% CI 1.19–1.96). Whereas homelessness (AOR = 0.67, 95% CI 0.50–0.91) was negatively associated with willingness. Conclusions: A high level of willingness to wear an overdose detection device was observed in this setting and a range of factors associated with overdose were positively associated with willingness. Since some factors, such as homelessness may be a barrier, further research is needed to investigate explanations for unwillingness and to evaluate real world acceptability of a wearable overdose detection devices as this technology becomes available.
Non-Newcomb-Benford Distributions
Creators: name: Kreiner, Welf Alfred
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Density function
subject: First-digit phenomenon
subject: Information
subject: Minerals
subject: Newcomb-Benford Law
subject: Populations
subject: Power function
subject: Probability
subject: Scale invariance
subject: Shannon entropy
subject: Weisser Jura
subject: DDC 500 / Natural sciences & mathematics
subject: Entropy
subject: Exponential functions
subject: Glass
subject: Granite
subject: Marble
subject: Meteorites
subject: Minerals
subject: Probabilities
subject: Stocks Prices
subject: Street addresses
subject: Wages
subject: Dichte (Stochastik)
subject: Entropie
subject: Fragment
subject: Glas
subject: Granit
subject: Meteorit
subject: Mineralstoff
subject: Population
subject: Gehalt
subject: Malm

description: Checking tables of statistical data, one finds that, in the first position of the numbers, the digits 1 to 9 occur with different frequency. Although in most cases the Newcomb-Benford Law applies (the 1 forms the leading decimal place 6.58 times as often as the 9), distributions have been found where the 1 in the first position occurs up to more than 40 times as frequently as the 9. The reason for this deviant behavior is discussed. The probability of the occurrence of a given first digit can be derived from a power function with a negative exponent P > 1. In addition, for some cases the first digits´ Shannon entropy is calculated.
La conjecture de Serre.
Creators: name: Khoury, Joseph.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1996
Subjects: subject: Mathematics.

description: Une des grandes reussites de l'algebre commutatif des annees soixante-dix etait la preuve de la "conjecture de Serre". Dans ces papiers, j'expose deux solutions differentes de cette conjecture. Les deux solutions sont exposees avec beaucoup de details de facon qu'un lecteur qui n'a pas une connaissance profonde en algebre commutatif puisse les comprendre sans beaucoup de difficultes.
Adjonctions et séries verbales dans les langues Gbe.
Creators: name: Tossa, Comlan Zéphirin.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Language, Linguistics.

description: La these debute par une esquisse syntaxique des langues Gbe qui prouve que ces langues sont de type SOV. Elle propose ensuite une analyse des constructions verbales serielles dans les langues Gbe a partir de l'hypothese que les langues naturelles peuvent avoir, en D-structure, des structures syntaxiques ou les categories V$\sp\circ$, V$\sp\prime$, VP et CP sont adjointes a V$\sp\prime$. L'existence de ces types d'adjonction est attestee a partir des series verbales, c'est-a-dire des enonces dans lesquels apparai t une sequence de deux lexemes verbaux pour former le predicat de la proposition. L'adjonction d'un V$\sp\circ$ a V$\sp\prime$ a ete attestee par l'existence de certains verbes qui ne peuvent recevoir aucun element de INFL mais qui expriment des aspects en se positionnant apres le verbe principal (et son complement). La position d'adjonction est justifiee, d'une part, par le fait que ces verbes agissent comme des complements qui viennent faire un apport semantique au verbe principal et d'autre part par l'etude du comportement de ces verbes par rapport a d'autres categories des langues Gbe. Les adjonctions d'un V$\sp\prime$ et d'un VP a V$\sp\prime$ ont ete etablies a partir d'un postulat descriptif qui permet de distinguer un V$\sp\prime$ d'un VP. L'idee est qu'une tete lexicale n'est pas toujours obligee de projeter jusqu'a la derniere projection maximale. On a une adjonction de V$\sp\prime$ quand la tete de ce V$\sp\prime$ est un verbe inaccusatif au sens de Burzio (1986). On a une adjonction de VP quand la tete est un verbe intransitif. L'adjonction d'un CP a trait a des cas ou une proposition entiere est percue comme un complement au verbe principal. Dans ces cas, C$\sp\circ$ (la tete de ce CP) est occupee par un morpheme specifique caracterise de morpheme de serialisation. Les constructions verbales serielles des langues Gbe ont ete analysees a partir de ces quatre types d'adjonction. Il a fallu d'abord distinguer une serialisation d'une auxiliation qui est le fait qu'un verbe, ordinairement plein, fonctionne dans certains contextes comme auxiliaire. Certaines formes d'adjonction impliquent la presence d'arguments nuls (sujet et objet) dans les constructions verbales serielles. Ces arguments nuls ont ete analyses comme etant de type pro et sont controles obligatoirement par des referents presents dans la phrase. (Abstract shortened by UMI.)
Turbulent Diffusion in Uniformly Sheared Flow
Creators: name: Vanderwel, Christina M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Fluid mechanics
Turbulence
Diffusion

description: The objective of this thesis research is to further the understanding of turbulent diffusion by experimentally studying the turbulent diffusion of a plume of dye released in uniformly sheared flow generated in a water tunnel. The flow studied was nearly homogeneous but strongly anisotropic and had a turbulent Reynolds number of 150. Maps of the turbulent velocity and dye concentration were measured simultaneously using stereoscopic particle image velocimetry and planar laser-induced fluorescence. A thorough analysis of the planar laser-induced fluorescence technique was performed; several previously unconsidered sources of error were identified and corrections were proposed. The measured evolutions of the mixed velocity-concentration statistics of the plume were compared with previous studies. The turbulent scalar flux vector was related to the mean concentration gradient through a first-order gradient transport model and, for the first time in an experimental flow, all components of the turbulent diffusivity tensor were measured directly. The turbulent diffusivity tensor was found to be highly anisotropic and its streamwise component appeared to be counter-gradient. The relative diffusion of the plume was also investigated and the evolution of the mean square particle separation was found to be consistent with Richardson-Obukhov scaling, with a value of Richardson's constant equal to 0.35. The fine structure of the concentration field and the mixed velocity-concentration statistics were also documented. Because of the high level of intermittency of the present plume, the scalar probability density function was strongly non-Gaussian and the conditional expectations of the velocity components and the scalar dissipation, conditioned upon the scalar value, were distinctly non-linear. Lastly, the role of coherent structures on scalar diffusion was investigated and a conditional eddy analysis demonstrated that hairpin vortices were associated closely with large scalar flux events.
Droit innu d'appartenance à la terre et droit de propriété : deux modes de penser l'univers et l'existence.
Creators: name: Foy, Suzanne H.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Law.

description: Le choix et le traitement de la problematique se de finissent comme suit: I. Conception innue du territoire. Analyse du discours innu sur le territoire afin de voir comment le peuple innu du Quebec concoit pour lui-meme sa relation a la terre et le titre qu'il dit detenir sur le territoire; examen du mode d'organisation sociale et juridique des Innus, y compris le nouveau projet de societe mis en avant par un peuple pret a s'inventer une nouvelle forme de modernite. II. Droit de propriete et pluralisme juridique. Exploration du pluralisme juridique au moyen de l'etude de l'origine et de l'evolution de la propriete, concept au coeur de la tradition juridique occidentale, de l'epoque feodale a nos jours; reflexions sur le rapport entre le droit innu d'appartenance a la terri et le droit de propriete, entre autres, au moyen de l'analyse des dichotomies societe moderne-societe traditionnelle/droit ecrit-droit oral; reflexions sur la question du piege des mots et sur la necessite d'entamer un dialogue interculturel menant a une reforme du droit canadien et quebecois dans le domaine foncier. III. Methodologie. Recours principalement a l'anthropologie juridique et a l'histoire du droit. Examen du discours innu sur le territoire et des travaux d'anthropologues quebecois s'y rapportant; utilisation de travaux d'anthropologues francais et d'historiens du droit afin d'etudier le rapport droit innu-droit civil dans un contexte qui tienne compte des categories et des logiques propres a deux traditions juridiques s'inscrivant dans des univers historiques et culturels distincts. (Abstract shortened by UMI.)
Supplementary document for Raman pure quartic solitons in Kerr microresonators - 5012067.pdf
Creators: name: Liu, Kewei
name: Yao, Shunyu
name: Yang, Changxi
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: This supplemental document contains the details of the numerical simulation model and analytical derivation in the stability analysis part
The influence of 'grey' literature on meta-analysis.
Creators: name: McAuley, Laura M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Health Sciences, General.

description: Introduction. The impact of the inclusion/exclusion of grey literature in meta-analysis (MA) is unclear. Objectives. To investigate, in a sample of published MA; the prevalence of grey literature, the quality of reporting at the MA and trial levels, and the impact of grey literature on the point estimate and precision of the results. Methods. Analysis of Variance and regression models were used to consider the quality of reporting and the impact of grey literature on estimates of efficacy. Results. Grey literature was included in 33% of the MA. Grey inclusive MA tended to be of higher quality than those that excluded it. At the trial level, grey literature was of lower quality than published literature. The exclusion of grey literature led to increases in both the reported effectiveness of the intervention and the precision of the results. Conclusions. MA that exclude grey literature run the risk of producing biased estimates of intervention effectiveness. Grey literature must be sought and included when it meets pre-defined inclusion criteria.
Elevated levels of N-terminal pro-brain natriuretic peptide in patients with chronic dyspnea and moderate renal dysfunction : decreased clearance or increased cardiac stress
Creators: name: Wieshammer, Siegfried
name: Dreyhaupt, Jens
name: Basler, Beate
Publisher: name: Universität Ulm
Year: 2011
Subjects: subject: Cardiac stress
subject: Renal dysfunction
subject: DDC 610 / Medicine & health
subject: Natriuretic peptide, Brain
subject: Dyspnea
subject: Heart diseases
subject: Brain natriuretic Peptide
subject: Atemnot
subject: Herzkrankheit

description: Background/Aims: Serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) are often increased in patients with impaired renal function. The objective of this study was to investigate whether the increase in NT-proBNP is predominantly due to a reduced renal clearance or an increased cardiac secretion. Methods: A series of 697 outpatients (age: 57.5 ± 16.4 years) referred for evaluation of dyspnea were assigned to 4 groups according to their estimated glomerular filtration rate [eGFR (ml/min per 1.73 m2)]: group 1, eGFR <60 (n = 77); group 2, eGFR ≧60 to <75 (n = 139); group 3, eGFR ≧75 to <90 (n = 191), and group 4, eGFR ≧90 (n = 289). The patients were also grouped into 2 categories based on the presence (n = 176) or absence (n = 521) of heart disease. Results: In patients with heart disease, the adjusted values for NT-proBNP were higher in eGFR group 1 than in eGFR groups 2–4 (p ≤ 0.01). In patients without heart disease, eGFR group 1 membership had no effect on NT-proBNP. Conclusion: A reduced renal clearance does not explain increased NT-proBNP levels in patients with moderate renal impairment and dyspnea. Our data suggest that a moderate reduction in renal function places additional stress on the heart in patients with established cardiac disease. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
The DEEP2 Galaxy Redshift Survey: The relationship between galaxy properties and environment at z ∼ 1
Creators: name: Cooper, Michael C.
name: Newman, Jeffrey A.
name: Croton, Darren
name: Weiner, Benjamin J.
name: Willmer, Christopher N.A.
name: Gerke, Brian F.
name: Madgwick, Darren S.
name: Faber, S. M.
name: Davis, Marc
name: Coil, Alison L.
name: Finkbeiner, Douglas P.
name: Guhathakurta, Puragra
name: Koo, David C.
Publisher: name: Swinburne
Year: 2024

description: We study the mean environment of galaxies in the DEEP2 Galaxy Redshift Survey as a function of rest-frame colour, luminosity, and [O ii] 3727 Å equivalent width. The local galaxy overdensity for >14 000 galaxies at 0.75 < z < 1.35 is estimated using the projected third-nearest-neighbour surface density. Of the galaxy properties studied, mean environment is found to depend most strongly on galaxy colour; all major features of the correlation between mean overdensity and rest-frame colour observed in the local universe were already in place at z∼ 1 . In contrast to local results, we find a substantial slope in the mean dependence of environment on luminosity for blue, star forming galaxies at z∼ 1 , with brighter blue galaxies being found on average in regions of greater overdensity. We discuss the roles of galaxy clusters and groups in establishing the observed correlations between environment and galaxy properties at high redshift, and we also explore the evidence for a 'downsizing of quenching' from z∼ 1 to ∼0. Our results add weight to existing evidence that the mechanism(s) that result in star formation quenching are efficient in group environments as well as clusters. This work is the first of its kind at high redshift and represents the first in a series of papers addressing the role of environment in galaxy formation at 0 < z < 1.
A Thousand Splendid Suns; Rhetorical Vision of Afghan Women
Creators: name: Kazemiyan, Azam
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Afghan Women
Fantasy Theme Analysis
Fictional Narratives
Patriarchy
Rhetorical Vision

description: Following the attacks on the World Trade Center and Pentagon, Afghan women suddenly gained high visibility all over the world. Since then, representations of Afghan women in the Western media and notably in the U.S. news media provide a critical concern to scholars. Much of the relevant literature on this topic speaks to the fact that the dominant portrayal of Afghan women in the Western media has shown them as passive victims of war and violence, to be liberated only by the Western military intervention. However, the question remains as to how the popular fictional narratives, as another vivid source of information, represent Afghan women to the Western readers. To address this question, A Thousand Splendid Suns, as a popular novel authored by Khalid Hosseini, an Afghan novelist, was selected. Bormannian fantasy theme analysis of this novel conveys the passivity of women in the context of Afghanistan. The findings reveal that the portrayals of Afghan women in the novel correspond with the images of Afghan women in the Western media. Moreover, an examination of a sample of book reviews of the novel unveils the important contribution of Khalid Hosseini to the Orientalist discourse.
Measuring livestock CH4 emissions with the laser methane detector: a review
Creators: name: Sorg, Diana
Publisher: name: My University
Year: 2022
Subjects: Datenverarbeitung

description: The handheld, portable laser methane detector (LMD) was developed to detect gas leaks in industry from a safe distance. Since 2009, it has also been used to measure the methane (CH4) concentration in the breath of cattle, sheep, and goats to quantify their CH4 emissions. As there is no consensus on a uniform measurement and data-analysis protocol with the LMD, this article discusses important aspects of the measurement, the data analysis, and the applications of the LMD based on the literature. These aspects, such as the distance to the animal or the activity of the animals, should be fixed for all measurements of an experiment, and if this is not possible, they should at least be documented and considered as fixed effects in the statistical analysis. Important steps in data processing are thorough quality control and reduction in records to a single point measurement or "phenotype" for later analysis. The LMD can be used to rank animals according to their CH4 breath concentration and to compare average CH4 production at the group level. This makes it suitable for genetic and nutritional studies and for characterising different breeds and husbandry systems. The limitations are the lower accuracy compared to other methods, as only CH4 concentration and not flux can be measured, and the high amount of work required for the measurement. However, due to its flexibility and non-invasiveness, the LMD can be an alternative in environments where other methods are not suitable or a complement to other methods. It would improve the applicability of the LMD method if there were a common protocol for measurement and data analysis developed jointly by a group of researchers. © 2021 by the author
Ce pilon à patate est un demi-dieu grec; le rôle de l’acteur–manipulateur dans le théâtre d’objets et dans l’adhésion du spectateur à la fiction théâtrale
Creators: name: Lehouillier, Lauriane
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: théâtre
objets
marionnettes
dénégation
manipulateur
Iliade

description: Le bon sens veut qu’une distance émotionnelle sépare l’humain de l’objet inerte, surtout si celui-ci est une chose fabriquée à des millions d’exemplaires et destinée à un usage quotidien et banal. Sauf exception, l’individu adulte n’est pas porté à développer un sentiment d’empathie pour une théière, une lavette, un rouleau à peinture ou une épingle à linges, tous des objets que l’on pourrait retrouver dans une scène de théâtre d’objets. Le théâtre d’objets, pourtant, s’efforce de créer de l’empathie entre l’humain et l’inanimé, de sorte que le spectateur en vienne à développer un rapport affectif avec le personnage-objet lorsque celui-ci est animé par un acteur-manipulateur (un manipul’acteur). Cette thèse de maîtrise se penche sur le phénomène de dénégation dans le théâtre d’objets et sur les façons dont l’acteur-manipulateur permet ou facilite l’adhésion du spectateur à la fiction scénique. Dans un premier temps, une étude de la littérature savante permettra de distinguer le théâtre de marionnette du théâtre d’objets, mais aussi d’examiner le rôle qu’y joue le manipulateur dans sa relation à l’objet et au public. Dans un second temps, il s’agira de mettre à l’épreuve ce savoir par un laboratoire expérimental de théâtre d’objets qui évaluera l’importance de la présence visible de l’acteur-manipulateur ainsi que de l’anthropomorphisation de l’objet dans le processus de dénégation du public et de son adhésion empathique pour l’inanimé. Nous déterminerons que c’est notamment par transfert mimétique du manipulateur vers l’objet que cette adhésion se fait.
Generation Y: an emerging entrepreneurial phenomenon
Creators: name: Hunt, Brian
name: Virasa, Thanaphol
Publisher: name: Swinburne
Year: 2024

description: In this paper we propose two frameworks for considering members of Generation Y as a body of entrepreneurs who are highly educated, technically and technologically literate, not averse to risk. If they have a family business background, Generation Y entrepreneurs are prepared to break the mould of entrepreneurship of their parents' generation. Generation Y entrepreneurs without a family business background are able to create a new mould for their entrepreneurial efforts.
Supplementary document for Coherent 2D electronic spectroscopy with complete characterization of excitation pulses during all scanning steps - 5012505.pdf
Creators: name: Pres, Sebastian
name: Kontschak, Laura
name: Hensen, Matthias
name: Brixner, Tobias
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Material
Mesenchymal stem cell secretome decreases the inflammatory response in annulus fibrosus organ cultures
Creators: name: Neidlinger-Wilke, Cornelia
name: Ekkerlein, Andreas
name: Goncalves, Raquel.M.
name: Ferreira, Joana M.
name: Ignatius, Anita
name: Wilke, Hans-Joachim
name: Teixeira, Graciosa Quelhas
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Herniation
subject: Repair/Regeneration
subject: Mechanical loading
subject: Paracrine signalling
subject: DDC 610 / Medicine & health
subject: Degeneration
subject: Hernia
subject: Complement (Immunology)
subject: Intervertebral Disc
subject: Inflammation
subject: Complement System Proteins
subject: Paracrine Communication
subject: Entzündung
subject: Komplement (Immunologie)

description: Mesenchymal stem/stromal cell (MSC)-based therapies have been proposed for back pain and disc degeneration, despite limited knowledge on their mechanism of action. The impact of MSCs/their secretome on annulus fibrosus (AF) cells and tissue was analysed in bovine AF organ cultures (AF-OCs) exposed to upper-physiological cyclic tensile strain (CTS, 9 %, 1 Hz, 3 h/d) and interleukin (IL)-1β in a custom-made device. A 4 d treatment of the CTS + IL-1β-stimulated AF-OCs with MSC secretome downregulated the expression of inflammation markers [IL-6, IL-8, prostaglandin-endoperoxide synthase 2 (PTGS2)], complement system regulators [cluster of differentiation (CD)46, CD55, CD59] and matrix metalloproteinase 1 but also of tissue inhibitors of metalloproteinases (TIMP-1, TIMP-2) and collagen type I. At the protein level, it was confirmed that IL-6, MMP-3 and collagen content was decreased in AF-OCs treated with the MSC secretome compared to the CTS + IL-1β stimulation alone. 9 d after treatment, a biomechanical peel-force test showed that the annular adhesive strength was significantly decreased by the MSC secretome treatment. Overall, MSC secretome had a stronger impact on AF tissue than MSCs in co-culture. The secretome contributed to a decrease in the inflammatory and catabolic status of AF cells activated by CTS + IL-1β and played a role in the regulation of the complement system. However, it also contributed to a decrease in collagen at the gene/protein level and in AF mechanical strength compared to the CTS + IL-1β stimulation alone. Therefore, the use of MSC secretome requires further investigation regarding its influence on disc matrix properties.
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 318 (42. Jg.), November 2012
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: DDC 050 / General serial publications
subject: Universities; Germany; Ulm
subject: Universität Ulm

description: N/A
Perceptions of nursing students of the impact that human patient simulation had on their clinical experience
Creators: name: Ogilvie, Susan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Health Sciences, Nursing.

description: This qualitative descriptive study captures reflections from third year baccalaureate nursing students who were asked to describe their experience with high fidelity human patient simulation (HPS) and the impact this experience had on their clinical reasoning skills. Currently educators in Ontario struggle to secure appropriate clinical placements for nursing students. Clinical practice is necessary for students to bridge the theory-practice gap and to become safe, competent practitioners. Nurses employ a clinical reasoning process in order to make health care decisions and it is through experience in practice that nurses develop that skill. Simulation is one way in which clinical reasoning skills can be developed. The study used individual interviews with six, third year nursing students who had participated in a quasi-experimental study where four days of their clinical time were spent in a high fidelity simulation laboratory. A detailed analysis of the transcribed data resulted in the emergence of the central theme of clinical confidence. Four interrelated components: realism, clinical scenarios, facilitation, and debriefing enhanced knowledge development and skill acquisition, which contributed to the development of confidence. Students were not able to articulate that HPS influenced their clinical reasoning skills; however, the four interrelated components contributed to the development of clinical reasoning. A focus group with five of the study participants followed the data analysis and confirmed the findings The study also provided insight into students' perceptions of effective teaching/learning strategies in simulation environments.
Transcriptomic Response of Saccharomyces cerevisiae during Fermentation under Oleic Acid and Ergosterol Depletion
Creators: name: Zara, Giacomo
name: Van Vuuren, Hennie J. J.
name: Mannazzu, Ilaria
name: Zara, Severino
name: Budroni, Marilena
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Under anaerobic/hypoxic conditions, Saccharomyces cerevisiae relies on external lipid supplements to modulate membrane lipid fraction in response to different stresses. Here, transcriptomic responses of two S. cerevisiae wine strains were evaluated during hypoxic fermentation of a synthetic must with/without ergosterol and oleic acid supplementation. In the absence of lipids, the two strains, namely EC1118 and M25, showed different behaviour, with M25 significantly decreasing its fermentation rate from the 72 h after inoculum. At this time point, the whole genome transcriptomic analysis revealed common and strain-specific responses to the lack of lipid supplementation. Common responses included the upregulation of the genes involved in ergosterol biosynthesis, as well as the seripauperin and the heat shock protein multigene families. In addition, the upregulation of the aerobic isoforms of genes involved in mitochondrial electron transport is compatible with the previously observed accumulation of reactive oxygen species in the two strains during growth in absence of lipids. Considering the strain-specific responses, M25 downregulated the transcription of genes involved in glucose transport, methionine biosynthesis and of those encoding mannoproteins required for adaptation to low temperatures and hypoxia. The identification of these pathways, which are presumably involved in yeast resistance to stresses, will assist industrial strain selection.
Factors associated with delay in response to symptoms of acute myocardial infarction.
Creators: name: Chew, Roderick T.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Health Sciences, Medicine and Surgery.

description: For patients with an acute myocardial infarction (AMI), the time from symptom onset to initiation of medical treatment is a critical determinant of outcome both for survival and for preservation of myocardial tissue. This is true because the effectiveness of thrombolytic therapy is, inversely related to time between onset of symptoms and initiation of therapy. Studies have shown that the time that patients take to decide to seek help accounts for most of the delay, a factor that has not improved despite efforts in education campaigns. Thus far, only two studies on delay time have been conducted in Canada. The study objective was to describe the delay time and investigate the factors associated with delay in response to symptoms of AMI in a Canadian setting. (Abstract shortened by UMI.)
Supplementary document for Coherent 2D electronic spectroscopy with complete characterization of excitation pulses during all scanning steps - 5012505.pdf
Creators: name: Pres, Sebastian
name: Kontschak, Laura
name: Hensen, Matthias
name: Brixner, Tobias
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplementary Material
Dataset zur Dissertation: Sustainable Change – Betrachtung von Veränderungsprozessen auf dem Weg zu mehr Nachhaltigkeit an den Beispielen von Fußballvereinen und kommunalen Haushalten
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Sustainable Change
subject: DDC 330 / Economics
subject: Sustainability
subject: Nachhaltigkeit
subject: Change Management

description: Die Daten umfassen die Transkripte, das Forschungsmodell sowie das erweiterte Forschungsmodell und das Codierungssystem aus MAXQDA. Dieses bildet die Grundlage für eine qualitative Inhaltsanalyse, welche im Rahmen der Dissertation "Sustainable Change – Betrachtung von Veränderungsprozessen auf dem Weg zu mehr Nachhaltigkeit an den Beispielen von Fußballvereinen und kommunalen Haushalten" durchgeführt wurde.
description: The data includes the transcripts, the research model as well as the extended research model and the coding system from MAXQDA. This forms the basis for a qualitative content analysis, which was carried out within the framework of the dissertation "Sustainable Change - Consideration of change processes on the way to more sustainability using the examples of football clubs and municipal households".
Erratum: The many lives of active galactic nuclei: Cooling flows, black holes and the luminosities and colours of galaxies (Monthly Notices of the Royal (2006) 365 (11-28))
Creators: name: Croton, Darren
name: Springel, Volker
name: White, Simon D.M.
name: De Lucia, G.
name: Frenk, C. S.
name: Gao, L.
name: Jenkins, A.
name: Kauffmann, G.
name: Navarro, J. F.
name: Yoshida, N.
Publisher: name: Swinburne
Year: 2024

description: Corrects an error in 'The many lives of active galactic nuclei: cooling flows, black holes and the luminosities and colours of galaxies' (Monthly Notices of the Royal Astronomical Society (2006) 365, pp. 11-28.
La vente sous contrôle de justice : comment le législateur se porte à la défense d'intérêts contradictoires.
Creators: name: Lafontaine, Michèle.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Law.

description: Notre these vise a cerner comment le legislateur reussit a defendre les interets contradictoires impliques dans le processus de vente sous controle de justice, tout en evitant d'en affecter l'efficacite. Nous avons souligne precedemment qu'une telle ambition necessite un minimum de coherence des normes applicables. Nous examinerons donc, dans un premier temps, comment les exigences de la vente sous controle de justice (I) affectent l'interpretation des regles edictees par le legislateur, tant au niveau des modes de vente que de leurs conditions essentielles. Cependant, dans la situation actuelle, force nous est d'admettre, des a present, que le legislateur a sous-estime la valeur d'un ensemble normatif coherent afin de rencontrer ces exigences. Partant, les consequences de la vente sous controle de justice (II) se manifestent tout d'abord dans l'interpretation de ses effets. Mais, inevitablement, toutes les lacunes se presentent comme une epee de Damocles sur la protection voulue. Alors, il est imperatif de comprendre le role confie a la personne designee qui, suivant l'absence d'un cadre rigoureux, devient un pivot essentiel permettant d'assurer l'equite ultimement recherchee. (Abstract shortened by UMI.)
A nonadaptive NC checker for permutation group intersection
Creators: name: Arvind, Vikraman
name: Torán, Jacobo
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Group theory. Data processing
subject: Permutation groups
subject: Theoretische Informatik

description: N/A
Strength of edge column-slab connections of post-tensioned concrete flat plates.
Creators: name: Sharifi, Haki.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Engineering, Civil.

description: The strength and behavior of edge column-slab connections of two way unbonded post-tensioned flat slab under uniformly distributed load were investigated. A square flat slab, two bays in each direction was constructed. The span of each bay was 3.2 m (10.5 ft) and the slab 89 mm (3.5 in) thick. Initially the slab behaved elastically and no residual deflections were observed upon releasing the load up to 5.8 kN/m$\sp2$ (0.85 psi). Punching shear failure happened at a load of 23.6 kN/m$\sp2$ at the edge column-slab connection #2. The failed connection(s) were repaired and shored, tendons re-tensioned and the slab reloaded to fail the next connection. To investigate the behaviour of corner column-slab connections all edge and the interior connections were shored. The measured moments and axial forces transferred to edge and corner columns were compared with those calculated by the Direct Design Method and Equivalent Frame Analysis. The shear strength obtained from the analysis of the experimental work was compared with previous research work, ACI 318-95 and CSA A23.3-94 concrete design codes and the 1995 Gardner proposed equation. (Abstract shortened by UMI.)
An MRM-Based multiplexed quantification assay for human adipokines and apolipoproteins
Creators: name: Krieg, Laura
name: Schaffert, Alexandra
name: Kern, Matthias
name: Landgraf, Kathrin
name: Wabitsch, Martin
name: Beck-Sickinger, Annette G.
name: Körner, Antje
name: Blüher, Matthias
name: Von Bergen, Martin
name: Schubert, Kristin
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Multiple reaction monitoring
subject: Targeted LC-MS
subject: Human serum
subject: SGBS cells
subject: Cell culture supernatant
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Adipokines
subject: Apolipoproteins
subject: Chromatography, Liquid
subject: Mass spectrometry
subject: Obesity
subject: Serum
subject: Adipokine
subject: Apolipoproteine
subject: LC-MS
subject: Fettsucht
subject: Blutserum

description: Adipokines and apolipoproteins are key regulators and potential biomarkers in obesity and associated diseases and their quantitative assessment is crucial for functional analyses to understand disease mechanisms. Compared to routinely used ELISAs, multiple reaction monitoring (MRM)-based mass spectrometry allows multiplexing and detection of proteins for which antibodies are not available. Thus, we established an MRM method to quantify 9 adipokines and 10 apolipoproteins in human serum. We optimized sample preparation by depleting the two most abundant serum proteins for improved detectability of low abundant proteins. Intra-day and inter-day imprecision were below 16.5%, demonstrating a high accuracy. In 50 serum samples from participants with either normal weight or obesity, we quantified 8 adipokines and 10 apolipoproteins. Significantly different abundances were observed for five adipokines (adipsin, adiponectin, chemerin, leptin, vaspin) and four apolipoproteins (apo-B100/-C2/-C4/-D) between the body mass index (BMI) groups. Additionally, we applied our MRM assay to serum samples from normal weight children and human adipocyte cell culture supernatants to proof the feasibility for large cohort studies and distinct biological matrices. In summary, this multiplexed assay facilitated the investigation of relationships between adipokines or apolipoproteins and phenotypes or clinical parameters in large cohorts, which may contribute to disease prediction approaches in the future.