cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Progress in gene therapy for neurological disorders
Creators: name: Gray, Steven J.
name: Boulis, Nicholas M.
name: Wilson, Thomas J.
name: Goins, William F.
name: Bennett, Jean
name: Wolfe, John H.
name: Castro, Maria G.
name: Simonato, Michele
name: Glorioso, Joseph C.
name: Vandenberghe, Luk H.
name: Fink, David J.
name: Lowenstein, Pedro R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Diseases of the nervous system have devastating effects and are widely distributed among the population, being especially prevalent in the elderly. These diseases are often caused by inherited genetic mutations that result in abnormal nervous system development, neurodegeneration, or impaired neuronal function. Other causes of neurological diseases include genetic and epigenetic changes induced by environmental insults, injury, disease-related events or inflammatory processes. Standard medical and surgical practice has not proved effective in curing or treating these diseases, and appropriate pharmaceuticals do not exist or are insufficient to slow disease progression. Gene therapy is emerging as a powerful approach with potential to treat and even cure some of the most common diseases of the nervous system. Gene therapy for neurological diseases has been made possible through progress in understanding the underlying disease mechanisms, particularly those involving sensory neurons, and also by improvement of gene vector design, therapeutic gene selection, and methods of delivery. Progress in the field has renewed our optimism for gene therapy as a treatment modality that can be used by neurologists, ophthalmologists and neurosurgeons. In this Review, we describe the promising gene therapy strategies that have the potential to treat patients with neurological diseases and discuss prospects for future development of gene therapy.
Влияние минеральной добавки «Рацион-плюс» на рост и развитие поросят
Creators: name: Назаренко Вячеслав Владимирович
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: Кормление свиней с учетом современных норм и потребностей во всех элементах питания является важным фактором повышения их продуктивности и состояние минеральной добавки «Рацион плюс» при откорме свиней показали, что, не обладая питательностью она оказала большое влияние на процессы обмена в организме животных, вследствие чего повысились продуктивные качества свиней.
Integrating Design Thinking in Teacher Education to Foster Creativity
Creators: name: Chapman, Olive
name: Pia, Jessica
name: Craigue, Kelly
name: Leiva-Sandino, Janeska
name: Godin, Scott
name: Hilton, Michael
Publisher: name: Papers on Postsecondary Learning and Teaching
Year: 2016

description: Papers on Postsecondary Learning and Teaching, Vol. 1 (2016)
Mechanical signals as anabolic agents in bone
Creators: name: Qin, Yi-Xian
name: Judex, Stefan
name: Ozcivici, Engin
name: Luu, Yen Kim
name: Rubin, Janet
name: Adler, Ben
name: Rubin, Clinton T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Aging and a sedentary lifestyle conspire to reduce bone quantity and quality, decrease muscle mass and strength, and undermine postural stability, culminating in an elevated risk of skeletal fracture. Concurrently, a marked reduction in the available bone-marrow-derived population of mesenchymal stem cells (MSCs) jeopardizes the regenerative potential that is critical to recovery from musculoskeletal injury and disease. A potential way to combat the deterioration involves harnessing the sensitivity of bone to mechanical signals, which is crucial in defining, maintaining and recovering bone mass. To effectively utilize mechanical signals in the clinic as a non-drug-based intervention for osteoporosis, it is essential to identify the components of the mechanical challenge that are critical to the anabolic process. Large, intense challenges to the skeleton are generally presumed to be the most osteogenic, but brief exposure to mechanical signals of high frequency and extremely low intensity, several orders of magnitude below those that arise during strenuous activity, have been shown to provide a significant anabolic stimulus to bone. Along with positively influencing osteoblast and osteocyte activity, these low-magnitude mechanical signals bias MSC differentiation towards osteoblastogenesis and away from adipogenesis. Mechanical targeting of the bone marrow stem-cell pool might, therefore, represent a novel, drug-free means of slowing the age-related decline of the musculoskeletal system.
Letter from Richard Trevino to Mark Wolfe, Temporary Curb Cuts at Cadet Circle, Randolph Air Force Base, Texas
Creators: name: Trevino, Richard
Publisher: name: Department of the Air Force, Air Education and Training Command
Year: 2010
Subjects: subject: Randolph Historic Landmark District
valueUri: https://core.tdar.org/browse/geographic-keyword/83184/randolph-historic-landmark-district
subject: Randolph Field
valueUri: https://core.tdar.org/browse/geographic-keyword/82870/randolph-field
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Randolph Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/78971/randolph-air-force-base
subject: Cadet Circle
valueUri: https://core.tdar.org/browse/other-keyword/153440/cadet-circle
subject: Curb
valueUri: https://core.tdar.org/browse/other-keyword/153441/curb
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: This memorandum provides documentation for the proposed temporary curb cuts at Cadet Circle located within the Randolph Field Historic Landmark District. It was determined that an undertaking exists, and will temporarily alter the design of the area. Attached to this memorandum is the undertaking and assessment report.
The phenotypic and genetic signatures of common musculoskeletal pain conditions
Creators: name: Diatchenko, Luda
name: Fillingim, Roger B.
name: Maixner, William
name: Smith, Shad B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Musculoskeletal pain conditions, such as fibromyalgia and low back pain, tend to coexist in affected individuals and are characterized by a report of pain greater than expected based on the results of a standard physical evaluation. The pathophysiology of these conditions is largely unknown, we lack biological markers for accurate diagnosis, and conventional therapeutics have limited effectiveness. Growing evidence suggests that chronic pain conditions are associated with both physical and psychological triggers, which initiate pain amplification and psychological distress; thus, susceptibility is dictated by complex interactions between genetic and environmental factors. Herein, we review phenotypic and genetic markers of common musculoskeletal pain conditions, selected based on their association with musculoskeletal pain in previous research. The phenotypic markers of greatest interest include measures of pain amplification and ‘psychological’ measures (such as emotional distress, somatic awareness, psychosocial stress and catastrophizing). Genetic polymorphisms reproducibly linked with musculoskeletal pain are found in genes contributing to serotonergic and adrenergic pathways. Elucidation of the biological mechanisms by which these markers contribute to the perception of pain in these patients will enable the development of novel effective drugs and methodologies that permit better diagnoses and approaches to personalized medicine.
The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b
Creators: name: Zhang, Yi
name: He, Jin
name: Tsukada, Yu-ichi
name: Kallin, Eric M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The Ink4a/Arf/Ink4b locus plays a critical role in both cellular senescence and tumorigenesis. Jhdm1b/Kdm2b/Fbxl10, the mammalian paralogue of the histone demethylase Jhdm1a/Kdm2a/Fbxl11, has been implicated in cell cycle regulation and tumorigenesis. In this report, we demonstrate that Jhdm1b is an H3K36 demethylase. Knockdown of Jhdm1b in primary MEFs inhibits cell proliferation and induces cellular senescence in a pRb and p53 pathway-dependent manner. Importantly, the effect of Jhdm1b on cell proliferation and cellular senescence is mediated through de-repression of p15Ink4b as loss of p15Ink4b function rescues cell proliferation defects in Jhdm1b knockdown cells. Chromatin immunoprecipitation on ectopically expressed Jhdm1b demonstrates that Jhdm1b targets the p15Ink4b locus and regulates its expression in an enzymatic activity-dependent manner. Alteration of Jhdm1b level affects Ras-induced neoplastic transformation. Collectively, our results indicate that Jhdm1b is an H3K36 demethylase that regulates cell proliferation and senescence through p15Ink4b.
Противозаклинивающее устройство конусного золотникового механизма газораспределения двигателя внутреннего сгорания
Creators: name: Харченко Валерий Семёнович
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: Предлагается устройство для противозаклинивания конического золотника в газораспределительном механизме двигателя внутреннего сгорания (ДВС).
Diagonals of separately continuous functions and their analogs
Creators: name: Karlova, Olena
name: Mykhaylyuk, Volodymyr
name: Sobchuk, Oleksandr
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Topology (math.GN)
subject: FOS: Mathematics
subject: 54C08, 54C05, 26B05

description: We prove that for a topological space $X$, an equiconnected space $Z$ and a Baire-one mapping $g:X\to Z$ there exists a separately continuous mapping $f:X^2\to Z$ with the diagonal $g$, i.e. $g(x)=f(x,x)$ for every $x\in X$. Under a mild assumptions on $X$ and $Z$ we obtain that diagonals of separately continuous mappings $f:X^2\to Z$ are exactly Baire-one functions, and diagonals of mappings $f:X^2\to Z$ which are continuous on the first variable and Lipschitz (differentiable) on the second one, are exactly the functions of stable first Baire class.
Повышение технико-эксплуатационных качеств гусеничного движителя мобильных уборочно-транспортных машин
Creators: name: Канделя Михаил Васильевич
name: Рябченко Виктор Николаевич
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: В статье рассмотрены цели и задачи применения мобильных уборочно-транспортных машин высокой проходимости. Потребность в таких машинах имеет место во многих отраслях народного хозяйства, особенно в регионах Дальнего Востока.
Non-Destructive Imaging of Breakdown Process in Ferroelectric Capacitors Using \textit{In-situ} Laser-Based Photoemission Electron Microscopy
Creators: name: Fujiwara, Hirokazu
name: Itoya, Yuki
name: Kobayashi, Masaharu
name: Bareille, Cédric
name: Shin, Shik
name: Taniuchi, Toshiyuki
Publisher: name: arXiv
Year: 2023
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: HfO$_2$-based ferroelectrics are one of the most actively developed functional materials for memory devices. However, in HfO$_2$-based ferroelectric devices, dielectric breakdown is a main failure mechanism during repeated polarization switching. Elucidation of the breakdown process may broaden the scope of applications for the ferroelectric HfO$_2$. Here, we report direct observations of a breakdown process in HfO$_2$-based ferroelectric capacitors, by \textit{in-situ} laser-based photoemission electron microscopy (laser-PEEM). We have not only clearly visualized the hard dielectric breakdown (HDB) spot, but also observed the regions responsible for the soft dielectric breakdown (SDB) which is a precursor phenomenon to HDB. It was found that the low-resistance region formed after SDB is wider than the conduction path formed after HDB. Furthermore, our spectromicroscopic analysis revealed that the photoelectron spectrum after SDB shows an enhancement in intensity without spectral-shape modulation, interpreted that the initially existed defects are increased. In the HDB spot, however, an additional shoulder structure was observed. These results provide spectroscopic evidence that the electronic states responsible for the conduction path after SDB are different from those after HDB. Through this work, we propose this microscopic approach as a versatile tool for studying buried materials as they are, accelerating the development of material engineering for advanced electronic devices.
description: 6 pages
Letter from Michael Grizer to Mark Wolfe, Installation of a Flag Pole at Building 1001, Fort Sam Houston, Texas
Creators: name: Grizer, Michael J.
Publisher: name: Department of the Air Force, Air Education and Training Command
Year: 2012
Subjects: subject: JBSA-Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/82532/jbsa-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/256/domestic-structures
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Domestic Structure or Architectural Complex
valueUri: https://core.tdar.org/browse/site-type/251/domestic-structure-or-architectural-complex
subject: Administrative Office Space
valueUri: https://core.tdar.org/browse/other-keyword/158207/administrative-office-space
subject: Medical Library
valueUri: https://core.tdar.org/browse/other-keyword/158719/medical-library
subject: Mast Style
valueUri: https://core.tdar.org/browse/other-keyword/158718/mast-style
subject: Flagpole
valueUri: https://core.tdar.org/browse/other-keyword/135140/flagpole
subject: Nurse's Quarters
valueUri: https://core.tdar.org/browse/other-keyword/152871/nurses-quarters
subject: Building 1001
valueUri: https://core.tdar.org/browse/other-keyword/152918/building-1001
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: Joint Base San Antonio is proposing an undertaking to install a mast style flagpole in front of building 1001 on Fort Sam Houston. Building 1001 was constructed in 1936 as is a property listed as eligible for the National Register of Historic Places. This building originally served as a medical library and nurse’s quarters and has been adaptively used for administrative offices.
Template strand scrunching during DNA gap repair synthesis by human polymerase λ
Creators: name: Pedersen, Lars C
name: Ramsden, Dale A
name: Perera, Lalith
name: Havener, Jody M
name: Krahn, Joseph M
name: Kunkel, Thomas A
name: Larrea, Andres A
name: Bebenek, Katarzyna
name: Garcia-Diaz, Miguel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Family X polymerases such as DNA polymerase (Pol ) are well suited for filling short gaps during DNA repair because they simultaneously bind both the 5' and 3' ends of short gaps. DNA binding and gap filling are well characterized for 1-nucleotide (nt) gaps, but the location of yet-to-be-copied template nucleotides in longer gaps is unknown. Here we present crystal structures revealing that, when bound to a 2-nt gap, Pol scrunches the template strand and binds the additional uncopied template base in an extrahelical position within a binding pocket that comprises three conserved amino acids. Replacing these amino acids with alanine results in less processive gap filling and less efficient NHEJ when 2-nt gaps are involved. Thus, akin to scrunching by RNA polymerase during transcription initiation, scrunching occurs during gap filling DNA synthesis associated with DNA repair.
D2.5 Interim report on case studies
Creators: name: Ferri, Delia
name: Martinelli, Arianna
name: Rossello, Giulia
name: Serra, M.Laura
Publisher: name: Zenodo
Year: 2021
Subjects: visual impairment
copyright

description: The project reCreating Europe examines stakeholders’ perspectives on the European copyright regulatory framework to promote a creative, diverse, and accessible Europe. Work Package (WP) 2 – End users and access to culture focuses on the role of end-users’ rights, interests, expectations, and behaviours vis-à-vis copyright rules. Task 2.5 - Empirical case studies on the effectiveness of regulatory measures to increase digital access to academics and people with visual impairments encompasses two empirical case studies assessing the impact of regulatory responses to paradigmatic access issues: (i) academics and the research exception, and (ii) visually impaired people and the so-called Marrakesh VIP exception. The two case studies are independently carried out. However, close communication and collaboration between the research teams in the case study design will allow comparability of data gathered. This interim report outlines the objectives of the two case studies, reviews relevant literature supporting the analysis of the case studies, lays out the specific research questions, and the methodology followed for the sampling and data collection. Please note: a screen-reader accessible version of this report can be downloaded via this link https://docs.google.com/uc?export=download&id=19bukOxlG8qDgIK9PrVdce3ox2oL0q4oL
Complexity of Government response to Covid-19 pandemic: A perspective of coupled dynamics on information heterogeneity and epidemic outbreak
Creators: name: Zhang, Xiaoqi
name: Fu, Jie
name: Hua, Sheng
name: Liang, Han
name: Zhang, Zi-Ke
Publisher: name: arXiv
Year: 2023
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: This study aims at modeling the universal failure in preventing the outbreak of COVID-19 via real-world data from the perspective of complexity and network science. Through formalizing information heterogeneity and government intervention in the coupled dynamics of epidemic and infodemic spreading; first, we find that information heterogeneity and its induced variation in human responses significantly increase the complexity of the government intervention decision. The complexity results in a dilemma between the socially optimal intervention that is risky for the government and the privately optimal intervention that is safer for the government but harmful to the social welfare. Second, via counterfactual analysis against the COVID-19 crisis in Wuhan, 2020, we find that the intervention dilemma becomes even worse if the initial decision time and the decision horizon vary. In the short horizon, both socially and privately optimal interventions agree with each other and require blocking the spread of all COVID-19-related information, leading to a negligible infection ratio 30 days after the initial reporting time. However, if the time horizon is prolonged to 180 days, only the privately optimal intervention requires information blocking, which would induce a catastrophically higher infection ratio than that in the counter-factual world where the socially optimal intervention encourages early-stage information spread. These findings contribute to the literature by revealing the complexity incurred by the coupled infodemic-epidemic dynamics and information heterogeneity to the governmental intervention decision, which also sheds insight into the design of an effective early warning system against the epidemic crisis in the future.
description: This version contains the full-resolution figures for the paper DOI: 10.1007/s11071-023-08427-5
On some papers of Nikiforov
Creators: name: Ning, Bo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: The well known Mantel's Theorem states that a graph on $n$ vertices and $m$ edges contains a triangle if $m>\frac{n^2}{4}$. Nosal proved that every graph on $m$ edges contains a triangle if the spectral radius $λ_1>\sqrt{m}$, which is a spectral analog of Mantel's Theorem. Furthermore, by using Motzkin-Straus Inequality, Nikiforov sharped Nosal's result and characterized the extremal graphs when the equality holds. Our first contribution in this note is to give two new proofs of the spectral concise Mantel's Theorem due to Nikiforov (without help of Motzkin-Straus Inequality). Nikiforov also obtained some results concerning the existence of consecutive cycles and spectral radius. Second, we prove a theorem concerning the existence of consecutive even cycles and spectral radius, which slightly improves a result of Nikiforov. At last, we focus on spectral radius inequalities. Hong proved his famous bound for spectral radius. Later, Hong, Shu and Fang generalized Hong's bound to connected graphs with given minimum degree. By using quite different technique, Nikiforov proved Hong et al.'s bound for general graphs independently. In this note, we prove a new spectral inequality by applying the technique of Nikiforov. Our result extends Stanley's spectral inequality.
description: 7 pages, accepted by Ars Combinatoria on September 16, 2014
An assessment of histone-modification antibody quality
Creators: name: Strome, Susan
name: Kuroda, Mitzi I
name: Gorchakov, Andrey A
name: Rechtsteiner, Andreas
name: Kharchenko, Peter V
name: Day, Daniel S
name: Ahringer, Julie
name: Alekseyenko, Artyom A
name: Cheung, Ming-Sin
name: Luu, Ying
name: Gu, Tingting
name: Kuan, Samantha
name: Riddle, Nicole C
name: Egelhofer, Thea A
name: Lee, Kyungjoon
name: Ngo, Queminh
name: Perry, Marc
name: Karpen, Gary H
name: Park, Peter J
name: Gadel, Sarah
name: Shanower, Gregory A
name: Schwartz, Yuri B
name: Ren, Bing
name: Latorre, Isabel
name: Linder-Basso, Daniela
name: Elgin, Sarah C R
name: Kolasinska-Zwierz, Paulina
name: Vielle, Anne
name: Pirrotta, Vincenzo
name: Minoda, Aki
name: Klugman, Sarit
name: Hawkins, R David
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: We report testing of the specificity and utility of over 200 antibodies raised against 57 different histone modifications, in Drosophila melanogaster, Caenorhabditis elegans and human cells. While most antibodies performed well, over 25% failed specificity tests by dot blot or western blot. Among specific antibodies, over 20% failed in chromatin immunoprecipitation experiments. We advise rigorous testing of histone-modification antibodies before use and provide a website for posting new test results.
A new species of dercetid and the assessment of the phylogeny of the Enchodontoidei (Teleostei: Aulopiformes)
Creators: Chida, Mori
Publisher: name: University of Alberta Library
Year: 2022

The Enchodontoidei is an extinct suborder of a marine teleost order Aulopiformes. Most enchodontoids have been reported from deposits of the Late Cretaceous. One of the major groups in Enchodontoidei is the family Dercetidae, which is traditionally characterized by an elongate body, long snout, triradiate dermal scutes, and reduced neural spines. Despite the long history of the taxonomic studies since the early 19th century, the phylogenetic study of enchodontoids including dercetids has been performed only relatively recently. The Enchodontoidei was recovered as a paraphyletic group in previous studies, and the family Dercetidae was supported by a single synapomorphy, neural spines very reduced. The two newly discovered specimens from southern Alberta are here assigned to a new species of the genus Dercetis, which were mainly reported from Europe and the Middle East in previous studies. The new species is recovered as a sister to the other species of Dercetis, but the family Dercetidae is not supported as a monophyletic taxon. The preexisting character matrix is modified based on the assessment of 87 characters, and the analysis with a modified character matrix recovered a monophyletic Enchodontoidei supported by a single unambiguous synapomorphy, maxilla included in gape. Overall, the description of the new specimens provides new insights into the genus Dercetis, and the assessment of the preexisting characters suggests the urgent need for additional modifications of the matrix and revision of the character coding in some taxa.
Исследования механизма действия препаратов для воздействия на детали двигателя внутреннего сгорания при его эксплуатации
Creators: name: Ломухин В.Б.
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: Препараты, воздействующие на трущиеся детали ДВС известны и разрабатываются различными изготовителями. В настоящее время отсутствует единая методика их испытаний, что затрудняет их объективное применение в ДВС. В настоящей работе проводятся трибологические испытания. Они позволяют осуществлять выбор препаратов улучшающих работу двигателя в зависимости от механизма действительного препарата. Это позволяет изменить техническое состояние механизма, увеличить безремонтный пробег, улучшить экологические показатели
Анализ динамики развития малого предпринимательства регионов Российской Федерации
Creators: name: Омаров М.М.
name: Омарова Н.Ю.
name: Шишкова Лариса Ивановна
name: Горлов Александр Владимирович
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: В статье рассматривается представление об уровне развития малого предпринимательства. Проведено исследование динамики развития его основных показателей во Владимирской, Ростовской, Челябинской, Новгородской, Томской, Амурской областях.
Intronic splicing enhancers, cognate splicing factors and context-dependent regulation rules
Creators: name: Ma, Meng
name: Wang, Zefeng
name: Wang, Yang
name: Xiao, Xinshu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: SummaryMost human genes produce multiple splicing isoforms with distinct functions. To systematically understand splicing regulation, we conducted an unbiased screen and identified >100 intronic splicing enhancers (ISEs) that were clustered by sequence similarity into six groups. All ISEs functioned in another cell type and heterologous introns, and their distribution and conservation patterns in different pre-mRNA regions are similar to exonic splicing silencers. Consistently all ISEs inhibited use of splice sites from exonic locations. The putative trans-factors of each ISE group were identified and validated. Five distinct ISE motifs were recognized by hnRNP H and F whose C-terminal domains were sufficient to render context-dependent activities of ISEs. The sixth group was controlled by factors that either activate or suppress splicing. This work provided a comprehensive picture of general ISE activities and provided new models of how a single element can function oppositely depending on its locations and binding factors.
Il terzo esercito: le memorie narranti della popolazione civile per un nuovo assetto del Museo della battaglia di Ortona [poster]
Il terzo esercito: le memorie narranti della popolazione civile per un nuovo assetto del Museo della battaglia di Ortona [poster]
Creators: name: Viola, Tito Vezio
Publisher: name: T. V. Viola, "Il terzo esercito: le memorie narranti della popolazione civile per un nuovo assetto del Museo della battaglia di Ortona", in Invito alla Storia. Terza Conferenza Nazionale dell'Associazione Italiana di Public HIstory AIPH 2019. Università della Campania "Luigi Vanvitelli", Santa Maria Capua Vetere e Caserta, 24-28 giugno 2019
Year: 2020

description: Il poster presenta il progetto di trasformazione e cambiamento del Museo della Battaglia di Ortona da un assetto espositivo lineare e sostanzialmente ancora rievocativo, ad un nuovo paradigma fondato sulle testimonianze dei sopravvissuti : quel “terzo esercito” di civili, portatori di narrazioni che vanno trasformate in memorie.
A complex network of factors with overlapping affinities represses splicing through intronic elements
Creators: name: Choudhury, Rajarshi
name: Wang, Zefeng
name: Li, Kai
name: Burge, Christopher B
name: Zhang, Jianming
name: Ma, Meng
name: Robertson, Alex
name: Xiao, Xinshu
name: Wang, Yang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: A cell-based screen for intronic splicing silencers revealed ten sequence motifs that inhibited splicing in human cells and either enhanced or inhibited exon inclusion when inserted into exons. Identification of trans-acting splicing factors for each motif revealed a complex network, which suggests that cis elements function differently in distinct cellular contexts, depending on the regulatory factors present.
OAHP Inventory, Building 4013 and Building 4014 General Purpose Warehouse, Fort Sam Houston, Texas
Creators: name: Walter, Chelsea
Publisher: name: Office of Archaeology and Historic Preservation
Year: 1978
Subjects: subject: Fort Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/83681/fort-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Non-Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/309/non-domestic-structures
subject: Building 4013
valueUri: https://core.tdar.org/browse/other-keyword/146637/building-4013
subject: Building 4014
valueUri: https://core.tdar.org/browse/other-keyword/146638/building-4014
subject: OAHP
valueUri: https://core.tdar.org/browse/other-keyword/138292/oahp
subject: General Purpose Warehouse
valueUri: https://core.tdar.org/browse/other-keyword/159025/general-purpose-warehouse
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: An inventory form by the Office of Archaeology and Historic Preservation for Building 4013 and Building 4014 at Fort Sam Houston, Texas. The structures were built in 1921 as general purpose warehouses.
Инвестиции и капитальные вложения в сельскохозяйственное производство Амурской области
Creators: name: Быхалов Петр Петрович
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: В статье рассматриваются некоторые подходы к вложению инвестиций в сельскохозяйственное производство Амурской области, организации сбытовой политики, позволяющие успешно преодолевать кризисные явления и добиваться устойчивого экономического роста.
Интенсификация соеводства – материальная основа повышения ее эффективности
Creators: name: Мигаль Наталья Александровна
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: Приведены результаты исследований за 2004-2005гг и перспективы развития соеводства в Амурской области до 2010 г. Отмечается необходимость сочетания экстенсивных и интенсивных факторов.
OAHP Inventory, Building 5023 Flagpole, Camp Bullis, Texas
Creators: name: Walter, Chelsea
Publisher: name: Office of Archaeology and Historic Preservation
Year: 1978
Subjects: subject: Fort Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/83681/fort-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Camp Bullis
valueUri: https://core.tdar.org/browse/geographic-keyword/82533/camp-bullis
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Non-Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/309/non-domestic-structures
subject: Flagpole
valueUri: https://core.tdar.org/browse/other-keyword/135140/flagpole
subject: OAHP
valueUri: https://core.tdar.org/browse/other-keyword/138292/oahp
subject: Building 5023
valueUri: https://core.tdar.org/browse/other-keyword/146661/building-5023
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: An inventory form by the Office of Archaeology and Historic Preservation for Building 5023 at Camp Bullis, Texas. The structure was built in 1930 as a flagpole.
Пути повышения эффективности сбора и транспортировки лесосечных отходов
Creators: name: Бобенко Виктор Фёдорович
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: В статье рассмотрены вопросы модернизации лесозаготовительных предприятий путем внедрения новых систем машин для сортиментной заготовки и переработки лесосечных отходов. Приведен анализ трех вариантов технологического процесса с применением машин для пакетирования порубочных остатков.
Sustainable water resources management in East and West African countries: the EWA -BELT project case studies
Creators: name: Georgiou Pantazis
name: Mattas Christos
name: Dimitra, Lazaridou
name: Mattas Konstadinos
name: Nastis Stefanos
Publisher: name: Zenodo
Year: 2022

description: Water is a vital natural resource for humans, plants, and animals to survive. Although it covers 71% of the earth’s surface, the total amount of fresh water that humanity can use to meet its demands constitutes a very small percentage of the total water amount on earth. In recent years there has been global concern about water availability. Water demands are increasing due to global population growth, human well-being and development, and intensification of economic activities. Climate change projections predict that drought periods will be prolonged, and floods will occur more frequently. Water supply will be threatened along with food and health security. In this context, the EWA-BELT project, funded by the European Union’s Horizon 2020 program, examines the human and ecological factors affecting water quality and quantity in case studies from West and East Africa countries (Ghana, Burkina Faso, Kenya, and Tanzania). It aims to analyze the impacts of water resources degradation on the environment and society, to propose strategies to address the problems, and to improve water resources management. For achieving these goals, the Driving Forces–Pressures–State–Impacts–Responses (DPSIR) framework, promoted by the European Environmental Agency, was implemented. DPSIR methodology has been used in literature for the development of indicators, for organizing the information contained in management plans, and for stakeholder communication. Some preliminary findings indicate that the main issues concerning water resources shortage in the surveyed areas are caused by population growth, intensive agriculture production, expansion of agriculture along with climate change, lack of infrastructure, and inadequate water management practices. Farmers’ income is reduced, and health issues arise over the years. Training programs to educate stakeholders, funding for equipment, establishment of a monitoring network, wastewater treatment, improvement/building of infrastructures, and implementation of integrated water resources management were identified as the most appropriate responses.
Современное состояние культур сосны обыкновенной на отвалах Райчихинского буроугольного месторождения
Creators: name: Алешичев Александр Николаевич
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: В статье на примере Райчихинского буроугольного месторождения рассмотрена проблема рекультивации и состояние лесных культур из сосны обыкновенной на техногенных ландшафтах. На основании исследований лесных культур с помощью закладки пробных площадей в разных частях Райчихинского лесничества проводится анализ роста, развития и продуктивности насаждений из сосны обыкновенной. Даны подробные таксационные характеристики состояния исследуемых насаждений по которым можно судить о перспективности создания в зеленой зоне города культур с участием этой породы.
Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function
Creators: name: Dohlman, Henrik G
name: Baker, Rachael
name: Cantley, Lewis C
name: Wilkerson, Emily M
name: Lewis, Steven M
name: Kuhlman, Brian
name: Sasaki, Atsuo T
name: Locasale, Jason W
name: Campbell, Sharon L
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: SUMMARYCell growth and differentiation are controlled by growth factor receptors coupled to the GTPase Ras. Oncogenic mutations disrupt GTPase activity leading to persistent Ras signaling and cancer progression. Recent evidence indicates that monoubiquitination of Ras leads to Ras activation. Mutation of the primary site of monoubiquitination impairs the ability of activated K–Ras to promote tumor growth. To determine the mechanism of human Ras activation we chemically ubiquitinated the protein and analyzed its function by NMR, computational modeling, and biochemical activity measurements. We established that monoubiquitination has little effect on Ras GTP binding, GTP hydrolysis, or exchange factor activation, but severely abrogates the response to GTPase activating proteins in a site–specific manner. These findings reveal a new mechanism by which Ras can trigger persistent signaling in the absence of receptor activation or an oncogenic mutation.
Generation of Intense High-Order Vortex Harmonics
Creators: name: Zhang, Xiaomei
name: Shen, Baifei
name: Shi, Yin
name: Wang, Xiaofeng
name: Zhang, Lingang
name: Wang, Wenpeng
name: Xu, Jiancai
name: Yi, Longqiong
name: Xu, Zhizhan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: This paper presents the method for the first time to generate intense high-order optical vortices that carry orbital angular momentum in the extreme ultraviolet region. In three-dimensional particle-in-cell simulation, both the reflected and transmitted light beams include high-order harmonics of the Laguerre-Gaussian (LG) mode when a linearly polarized LG laser pulse impinges on a solid foil. The mode of the generated LG harmonic scales with its order, in good agreement with our theoretical analysis. The intensity of the generated high-order vortex harmonics is close to the relativistic region, and the pulse duration can be in attosecond scale. The obtained intense vortex beam possesses the combined properties of fine transversal structure due to the high-order mode and the fine longitudinal structure due to the short wavelength of the high-order harmonics. Thus, the obtained intense vortex beam may have extraordinarily promising applications for high-capacity quantum information and for high-resolution detection in both spatial and temporal scales because of the addition of a new degree of freedom.
Photographs, The Quadrangle and Clock Tower, Fort Sam Houston, Texas
Creators: name: SSG Burchfield
Publisher: name: Central Photo Facility, US Army
Year: 1973
Subjects: subject: JBSA-Sam Houston
valueUri: https://core.tdar.org/browse/geographic-keyword/82532/jbsa-sam-houston
subject: San Antonio
valueUri: https://core.tdar.org/browse/geographic-keyword/4149/san-antonio
subject: Comal (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3222/comal-county
subject: Bexar (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/4150/bexar-county
subject: Grayson Street
valueUri: https://core.tdar.org/browse/geographic-keyword/83288/grayson-street
subject: Texas
valueUri: https://core.tdar.org/browse/geographic-keyword/6923/texas
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/318/governmental-structure
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Military Structure
valueUri: https://core.tdar.org/browse/site-type/322/military-structure
subject: Non-Domestic Structures
valueUri: https://core.tdar.org/browse/site-type/309/non-domestic-structures
subject: Quad 10
valueUri: https://core.tdar.org/browse/other-keyword/158663/quad-10
subject: Fifth U.S. Army Headquarters
valueUri: https://core.tdar.org/browse/other-keyword/158661/fifth-us-army-headquarters
subject: Clocktower
valueUri: https://core.tdar.org/browse/other-keyword/158662/clocktower
subject: Building 40
valueUri: https://core.tdar.org/browse/other-keyword/146155/building-40
subject: Quadrangle
valueUri: https://core.tdar.org/browse/other-keyword/146777/quadrangle
subject: Sallyport
valueUri: https://core.tdar.org/browse/other-keyword/156809/sallyport
subject: Building 16
valueUri: https://core.tdar.org/browse/other-keyword/146154/building-16
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Historic Background Research
valueUri: https://core.tdar.org/browse/investigation-type/18/historic-background-research
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: Black and white photographs taken in 1973 of the Quadrangle and Clock Tower at Fort Sam Houston, Texas. Each photograph details a different area of the two subjects from different directions.
Large-Scale MIMO versus Network MIMO for Multicell Interference Mitigation
Creators: name: Hosseini, Kianoush
name: Yu, Wei
name: Adve, Raviraj S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: This paper compares two important downlink multicell interference mitigation techniques, namely, large-scale (LS) multiple-input multiple-output (MIMO) and network MIMO. We consider a cooperative wireless cellular system operating in time-division duplex (TDD) mode, wherein each cooperating cluster includes $B$ base-stations (BSs), each equipped with multiple antennas and scheduling $K$ single-antenna users. In an LS-MIMO system, each BS employs $BM$ antennas not only to serve its scheduled users, but also to null out interference caused to the other users within the cooperating cluster using zero-forcing (ZF) beamforming. In a network MIMO system, each BS is equipped with only $M$ antennas, but interference cancellation is realized by data and channel state information exchange over the backhaul links and joint downlink transmission using ZF beamforming. Both systems are able to completely eliminate intra-cluster interference and to provide the same number of spatial degrees of freedom per user. Assuming the uplink-downlink channel reciprocity provided by TDD, both systems are subject to identical channel acquisition overhead during the uplink pilot transmission stage. Further, the available sum power at each cluster is fixed and assumed to be equally distributed across the downlink beams in both systems. Building upon the channel distribution functions and using tools from stochastic ordering, this paper shows, however, that from a performance point of view, users experience better quality of service, averaged over small-scale fading, under an LS-MIMO system than a network MIMO system. Numerical simulations for a multicell network reveal that this conclusion also holds true with regularized ZF beamforming scheme. Hence, given the likely lower cost of adding excess number of antennas at each BS, LS-MIMO could be the preferred route toward interference mitigation in cellular networks.
description: 13 pages, 7 figures; IEEE Journal of Selected Topics in Signal Processing, Special Issue on Signal Processing for Large-Scale MIMO Communications
Lewin et al., Long-term cellulose enrichment selects for highly cellulolytic consortia and competition for public goods: Supplemental Material
Creators: name: Lewin, Gina
name: Davis, Nicole M.
name: R. McDonald, Bradon
name: J. Book, Adam
name: Chevrette, Marc G.
name: Suh, Steven
name: Boll, Ardina
name: Currie, Cameron R.
Publisher: name: figshare
Year: 2020
Subjects: subject: 60504 Microbial Ecology
subject: FOS: Biological sciences

description: Supplemental methods, Figs S1-S7, Tables S1 and S2, Datasets S1-S3, and supplemental references for the manuscript "Long-term cellulose enrichment selects for highly cellulolytic consortia and competition for public goods" by Gina R. Lewin, Nicole M. Davis, Bradon R. McDonald, Adam J. Book, Marc G. Chevrette, Steven Suh, Ardina Boll, and Cameron R. Currie
A search for decay $η' \rightarrow 4 π^{0}$ with GAMS-$4π$ Setup
Creators: name: Donskov, S. V.
name: Kolosov, V. N.
name: Lednev, A. A.
name: Mikhailov, Yu. V.
name: Polyakov, V. A.
name: Samoylenko, V. D.
name: Khaustov, G. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A search for rare decay $η' \rightarrow 4 π^{0}$ has been performed with GAMS-4$π$ Setup. The new upper limit for decay was established $BR(η' \rightarrow 4 π^{0}) < 3.2 \cdot 10^{-4}$ at 90\% confidence level. The $π^{-} p$ charge-exchange reaction at 32.5 GeV/c was used as a source of $1.3\cdot 10^{6}$ $ η'$ mesons. Experiment carried out at the IHEP U-70 accelerator.
description: 5 pages, 4 figures
Продуктивность и состояние брусничников Зейского лесхоза
Creators: name: Кондратенко Валентина Владимировна
Publisher: name: Дальневосточный аграрный вестник
Year: 2007

description: В статье изложены результаты исследований по изучению продуктивности и состоянию брусничников Зейского лесхоза. Отмечено, что продуктивность брусники тесно связана с полнотой древостоя и промежутком времени, прошедшем после рубки. Брусника растет преимущественно в лиственничных и сосновых древостоях с полнотой 0,3 – 0,4, в которых создаются оптимальные световые условия для дикорастущих ягодников. Установлены причины сокращения площадей брусничников и снижения их биологической продуктивности.