cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The complex testing control of students’ motor abilities aged 17-20 years
Creators: name: Sergienko, Vladimir
Publisher: name: figshare
Year: 2013
Subjects: Education

description: Directions of evaluation of motive capabilities of students are considered. It is used 12 ball sigmoid scale of the American test complex (YMСA). In research took part 1200 students up-diffused on according to ages 17, 18, 19, 20. It is marked a tendency to the decline of middle indexes of motive capabilities with the increase of age of students. The indexes of development of power capabilities, capacity for endurance and flexibility and their complex testing are described. Measures are offered on the increase of motivation of students to the improvement of results of motive preparedness in the process of physical education. The indexes of testing of the level of motive preparedness of students allow to compare them during all period of studies, to estimate and carry out their analysis. The method of complex estimation allowed high-quality estimate on «satisfactorily» motive preparedness of students of different age within the limits of 61,7-65,7%.
THE ROLE OF SH. KHOLMIRZAEV'S WORK IN THE UZBEK STORYTELLING OF THE PERIOD OF INDEPENDENCE.
Creators: name: Ergasheva, Aziza
Publisher: name: Zenodo
Year: 2024

description: This article analyzes Shukur Kholmirzayev and his works written during the period of independence.The author's creativity occurs in all components of the work, through a unique artistic interpretation.
The functional model of optimization of the special physical preparation of students in the period of flying practice
Creators: name: Kirpenko, Vitaly
Publisher: name: figshare
Year: 2013
Subjects: Education

description: It is considered approaches to optimization special physical preparation of students during the period of flying practice. For the construction of functional model of such system new information IDEF technology is utillized (ICAM Definition). The feature of technology is gradual introduction all large levels of working out in detail (decoupligs). It is marked that it is expedient to carry out a decouplig before functions which will realize leaders of physical preparation and instructor of flying preparation. It is well-proven that on the stage of research of function a fundamental place is occupied by a functional design. The result of optimization of maintenance of teaching is systematization of knowledge, abilities, facilities of development and support professionally of meaningful qualities of students. The hierarchical levels of process of systematization of maintenance of teaching are recommended. It is offered directions of realization of functional model through conditioning optimization of pedagogical activity of teacher.
Wallanlagen_Karlsruhe
Creators: name: Bernard, Loup
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017

description: Enceintes pré- et protohistoriques de la région de Karlsruhe. Transcription de l'ouvrage : Christoph Morrissey, Dieter Müller mit Beiträgen von Günther Wieland Vor- und frühgeschichtliche Befestigungen 27. Wallanlagen im Regierungsbezirk Karlsruhe ISBN: 978-3-8062-2790-1
ЎЗБЕКИСТОН РЕСПУБЛИКАСИДА ИНВЕСТИЦИЯ ЛОЙИҲАЛАРИ ЁРДАМИДА САНОАТ СОҲАСИНИНГ ҲОЛАТИ ВА РИВОЖЛАНТИРИШ ТЕНДЕНЦИЯЛАРИ
Creators: name: Исроилов, Дилшодбек
Publisher: name: Zenodo
Year: 2024

description: Ушбу илмий мақолада Ўзбекистон Республикасида саноат соҳасини яқин уч йиллик ҳолати, инвестиция лойиҳаларини саноат соҳасига жалб қилиниши кенг ёритиб берилган. Саноат соҳасини ривожлантиришда мамлакатимизда қўлланилиши режалаштирилган чора-тадбирлар ҳам кўрсатилган.
The problem of the quality of judging in rhythmic gymnastics.
Creators: name: Perederij, Vera
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The aim of the study is to develop a classification of factors influencing the quality of judging in rhythmic gymnastics. As a result of consolidation of theoretical information and practical experience was a list of the factors that negatively affect the behavior of judges in gymnastics, which were divided into two groups: the objective and non-objective (subjective). Objective factors include intense competition schedule, fatigue, especially memory, attention, competition rules, to the subjective: the ratio of judges to their gymnast (team) or to the opposing team, the lack of interest in the performance, composition of the judging panel, the influence of authority and popularity sportswomen dependence on its management. Respondents were unanimous in that independent professional judges are needed in a rhythmic gymnastics. It is set that 64% respondent mark the presence of pressure on judges from the side of competitors.
Doctors & patients : supply, use and payments in British Columbia, 1998-1999 : part I - physician FTEs and distribution in B.C.
Creators: name: Kazanjian, Arminée, 1947-
name: Chen, Alice W.
name: Wood, Laura Christine, 1955-
name: Fung, Patrick Wong
Publisher: name: Health Human Resources Unit (HHRU)
Year: 2014

description: This report on physician supply and utilization in B.C. is a revised version of the Fee Practice Medical Service Expenditures per Capita and Full-time-equivalent Physicians in B.C. reports previously published by the Health Human Resources Unit (HHRU), in response to ongoing concern about supply and distribution of physicians in the province. The purpose of the reports, therefore, is to provide descriptive information to medical service planners for their reference. This current report includes data about physician full-time-equivalent supply and utilization in each health authority and by specialty for the year 1998-99. Physician supply may be measured in both head counts and as estimates of full-time equivalents (FTEs). Each measure gives a different estimate of the availability of physician services. This report provides data on both measures.
Projektpräsentation ELADOAH: Forschungsbericht zu gemeinschaftlichen Publikationsmodellen
Creators: name: Henkes, Lena Marie
name: Wrzesinski, Marcel
name: Holscher Blackman, Katherina
Publisher: name: Zenodo
Year: 2024
Subjects: Open Access
Diamond Open Access

description: Wie kann Diamond Open Access als Publikationsmodell in Deutschland langfristig organisiert und nachhaltig finanziert werden? Im Rahmen der Thematischen Sprechstunde der Landesinitiative openaccess.nrw stellen Lena Marie Henkes, Marcel Wrzesinski und Katherina Holscher Blackman erste Zwischenergebnisse aus dem Forschungsprojekt ELADOAH vor und geben Einblicke in die Durchführung einer Interviewstudie. 

Das Projekt "Erwerbungslogik als Diamond-Open-Access-Hindernis: Aus-, Um- und Nebenwege" (ELADOAH) ist vom Bundesministerium für Bildung und Forschung gefördert (Förderkennzeichen: 16KOA027).
Ubiquitous Computing and Natural Interfaces for Environmental Information
Creators: name: Almeida, Diogo
Publisher: name: figshare
Year: 2013
Subjects: Environmental Science
Design
Theoretical Computer Science
Applied Computer Science

description: The next computing revolution’s objective is to embed every street, building, room and object with computational power. Ubiquitous computing (ubicomp) will allow every object to receive and transmit information, sense its surroundings and act accordingly, be located from anywhere in the world, connect every person. Everyone will have the possibility to access information, despite their age, computer knowledge, literacy or physical impairment. It will impact the world in a profound way, empowering mankind, improving the environment, but will also create new challenges that our society, economy, health and global environment will have to overcome. Negative impacts have to be identified and dealt with in advance. Despite these concerns, environmental studies have been mostly absent from discussions on the new paradigm. This thesis seeks to examine ubiquitous computing, its technological emergence, raise awareness towards future impacts and explore the design of new interfaces and rich interaction modes. Environmental information is approached as an area which may greatly benefit from ubicomp as a way to gather, treat and disseminate it, simultaneously complying with the Aarhus convention. In an educational context, new media are poised to revolutionize the way we perceive, learn and interact with environmental information. cUbiq is presented as a natural interface to access that information.
Case Study: Blue City Challenge
Creators: name: LOBA - Customer Experience Design
name: Avans University of Applied Sciences
name: University of Bologna
name: FVA New Media Research (Italy)
name: Q PLAN International (Greece)
Publisher: name: Zenodo
Year: 2024

description: Explore this case study collected by BioGov.net partners in Netherlands! This valuable resource provides a quick and comprehensive understanding of the amazing Blue City Challenge Initiative case study.
THE STUDY OF SELF-CONCEPT BETWEEN VOLUNTEER AND NON-VOLUNTEER STUDENTS IN SPORT OF UNIVERSITIES
Creators: name: Benar Noshin
name: Andam, Reza
name: Asieh Ghorbanian Rajabi
Publisher: name: figshare
Year: 2013
Subjects: Education

description: Understanding personality characteristics of volunteers are important for their recruitment and retention in sport associations. This study compared self-concept as a personality characteristic between volunteer and non-volunteer students in sport associations. The method of this research was survey and descriptive. The statistical population consisted of volunteer and non-volunteer students in sport associations of Iran universities. Two hundred and fifty two students (120 volunteers and 132 non-volunteers) from 10 universities were selected as subjects by using random clustered sampling method. Pyryt and Mandaglio Self Perceived Survey (PMSPS) was used to collect the data. The content and face reliability of questionnaire was checked and confirmed. Cronbach’s alpha coefficient was used to test the reliability of the questionnaire (alfa=0.90). Independent t test and U Mann-Whitney test were used for comparison of the factors between volunteers and non-volunteers. Findings of this study indicated that there was a significant difference between volunteer and non-volunteer students in social and athletic self-concept. The mean of scientific and value factors were higher in volunteers than non-volunteers, however, they were not statistically significant. We concluded that the nature of sport (active) and sport volunteering (social) encourage students who have higher self-concept for volunteering. Moreover, the characteristics of sport associations can increase self-concept in sport volunteers.
Validation of the Integrated Biosphere Simulator over Canadian deciduous and coniferous boreal forest stands
Creators: name: Delire, Christine
name: Price, David T.
name: El Maayar, Mustapha
name: Black, T. Andrew
name: Foley, Jonathan A.
name: Bessemoulin, Pierre
Publisher: name: American Geophysical Union
Year: 2011

description: Data collected during the Boreal Ecosystem-Atmosphere Study (BOREAS) at four different forest stands were used to test surface energy and carbon fluxes simulated by the Integrated Biosphere Simulator (IBIS). These stands included deciduous and conifer species and were located in both the BOREAS northern and southern study areas. Two runs were made: one using the original IBIS model and the other using a version modified to consider an organic soil layer (OSL) covering the mineral soil surface. Results show that the inclusion of the OSL substantially improved the simulation of soil heat flux, as well as of temperature and moisture in the topmost soil layer. Simulations show that latent and sensible heat fluxes, and net ecosystem exchange of carbon, were not affected appreciably by the presence of a thin (10 cm or less) OSL covering the forest floor. With a thick (50 cm) OSL, however, simulation of latent heat flux and net ecosystem exchange of carbon was substantially improved. Consideration of the OSL in the model also led to better simulation of the onsets of soil thawing. Correct estimation of heat diffusion to deep soil through thick organic layers requires a parameterization that accounts for the state of the organic material decomposition. Simulations presented here also show the necessity for using detailed information on soil physical properties for better evaluation of model performance. An edited version of this paper was published by AGU. Copyright 2011 American Geophysical Union.
Responses of five species of coniferophagous bark beetles (Coleoptera: Scolytidae) to angiosperm bark volatiles
Creators: name: Huber, Dezene
Publisher: name: figshare
Year: 2013
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology

description: Ph.D. thesis by Dezene Huber entitled: Responses of five species of coniferophagous bark beetles (Coleoptera: Scolytidae) to angiosperm bark volatiles Defended April 2001, Simon Fraser University, Department of Biological Sciences. Senior supervisor: Dr. John H. Borden
Resolving phylogenetic relationships within the order Enoplida (Phylum Nematoda)
Creators: name: Bik, Holly
Publisher: name: figshare
Year: 2013
Subjects: subject: Molecular Biology
subject: Marine Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Evolutionary Biology

description: Please cite this publication as follows: Bik, H.M. (2010) Resolving phylogenetic relationships within the order Enoplida (Phylum Nematoda). PhD Thesis, University of Southampton, UK.
Characterization of the chemical resistance of two non-vulcanized styrene–butadiene rubbers (SBR)
Creators: name: Kempis, Florian
name: Orlowsky, Jeanette
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: alkali resistance
subject: AR glass
subject: durability
subject: polymers
subject: SBR
subject: textile concrete
subject: 690

description: The objective of this series of tests is to characterize the alkali and water resistance of two non-vulcanized formulations based on co-polymerizing styrene–butadiene rubbers (SBR1 and SBR2). The relative merits of the two polymer systems as impregnating agents for alkali-resistant glass reinforcement in cementitious binders are assessed. For this purpose, polymer films were synthesized and then chemically conditioned for up to half a year at temperatures of 23 °C and 50 °C in sodium hydroxide and potassium hydroxide solutions as well as in salt and distilled water. Changes in mass, tensile strength, and material hardness were evaluated to assess the chemical resistance of the two polymer systems. The different test liquids generally led to swelling (increase in mass) and degradation (reduction in mass) of the polymer structures. These two processes occurred simultaneously. The liquid absorption capacity of the SBR1 impregnation system was between 25.05% and 51.60% by weight, depending on the test liquids. In contrast, the SBR2 impregnation system exhibited a lower liquid absorption capacity, with a weight increase from 21.19% to 42.90%. The chemical conditioning resulted in a maximum mass reduction of the polymer structure SBR1 of 8.82% by weight. The polymer SBR2, on the other hand, only lost up to 2.88% by weight. The tensile strengths of the unconditioned samples of the polymer systems SBR1 and SBR2 were 55.49 ± 7.47 N and 80.87 ± 15.96 N, respectively. The test liquids caused a reduction in strength over the storage period which was accelerated by increased temperatures. The loss of strength of the polymer structure SBR2 was lower over the entire conditioning period. In this context, a correlation was found between strength and material hardness. Overall, the polymeric impregnation system SBR2 had a lower liquid absorption capacity and a lower degree of damage caused by the degrading test liquids. Furthermore, the tensile strength was generally higher and more robust over the entire conditioning period. The results of the durability tests indicate that the SBR2 polymer system is more suitable for use in cementitious binders, as it exhibits less degradation of the polymer structure in response to chemical aging processes.
description: Materials;17(12)
Quinazoline sulfonamide derivatives targeting MicroRNA-34a/MDM4/p53 apoptotic axis with radiosensitizing activity
Creators: name: Soliman, Aiten M
name: Kodous, Ahmad S
name: Al-Sherif, Diana A
name: Ghorab, Mostafa M
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: Aim: New quinazoline benzenesulfonamide hybrids 4a–n were synthesized to determine their cytotoxicity and effect on the miR-34a/MDM4/p53 apoptotic pathway. Materials & methods: Cytotoxicity against hepatic, breast, lung and colon cancer cell lines was estimated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Results: Compound 4d was the most potent against HepG2 and MCF-7 cancer cells, with potential apoptotic activity verified by a significant upregulation of miR-34a and p53 gene expressions. The apoptotic effect of 4d was further investigated and showed downregulation of miR-21, VEGF, STAT3 and MDM4 gene expression. Conclusion: The anticancer and apoptotic activities of 4d were enhanced post irradiation by a single dose of 8 Gy γ-radiation. Docking analysis demonstrated a valuable affinity of 4d toward VEGFR2 and MDM4 active sites. New quinazoline benzenesulfonamide derivatives were designed and synthesized. Cytotoxic activity was measured against MCF-7, HepG2, A549 and Lovo cells. Evaluation of the miRNA-34a/MDM4/p53 apoptotic pathway was undertaken to identify the most potent compound. Compound 4d induces apoptosis and possesses radiosensitizing activity. Molecular docking was performed in the active sites of VEGFR and MDM4.
Asymptomatic Bacteriuria in Pregnancy : Rapid answers using the Cochrane Library
Creators: name: Therapeutics Initiative (University Of British Columbia)
Publisher: name: The University of British Columbia
Year: 2023

description: Therapeutics Letter 41 considers treatment of asymptomatic bacteriuria in pregnancy using Cochrane systematic review evidence. Reliable sources of best available evidence are an aid to practice. The Cochrane Library is a recognizably incomplete but expanding source of best available evidence. Familiarity with the Cochrane Database of Systematic Reviews is necessary in order to be able to extract information effectively and efficiently.
Facile synthesis and in silico studies of benzothiazole-linked hydroxypyrazolones targeting α-amylase and α-glucosidase
Creators: name: Punia, Ravinder
name: Mor, Satbir
name: Khatri, Mohini
name: Kumar, Deepak
name: Das, Priyanku Pradip
name: Jindal, Deepak Kumar
name: Kumar, Ashwani
name: Selvaraj, Prem
name: Kumar, Rajnish
name: Mohil, Rajni
name: Jakhar, Komal
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Space Science
Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Aim: The objective of the present investigation was to design and synthesize new heterocyclic hybrids comprising benzothiazole and indenopyrazolone pharmacophoric units in a single molecular framework targeting α-amylase and α-glucosidase enzymatic inhibition. Materials & methods: 20 new benzothiazole-appended indenopyrazoles, 3a–t, were synthesized in good yields under environment-friendly conditions via cycloaddition reaction, and assessed for antidiabetic activity against α-amylase and α-glucosidase, using acarbose as the standard reference. Results: Among all the hydroxypyrazolones, 3p and 3r showed the best inhibition against α-amylase and α-glucosidase, which finds support from molecular docking and dynamic studies. Conclusion: Compounds 3p and 3r have been identified as promising antidiabetic agents against α-amylase and α-glucosidase and could be considered valuable leads for further optimization of antidiabetic agents. A series of 20 benzothiazole-appended indenopyrazoles were synthesized in good yields. Structural confirmation of the newly synthesized compounds was ascertained by spectral analysis data and finally by single-crystal x-ray crystallography. The titled compounds were screened for their in vitro antidiabetic activity. Among all the derivatives, 3p and 3r exhibited promising inhibitory activity against both enzymes, α-amylase and α-glucosidase. Enzymatic inhibition was supported by docking studies of compounds 3p with binding energies of -10.3 and -10.4 kcal/mol and 3r with binding energies of -10.3 and -10.7 kcal/mol for α-amylase and α-glucosidase, respectively. The docked complexes of the most active compound, 3r, with α-amylase and α-glucosidase were subjected to molecular dynamics study to check the complex stability and the ligand–target interactions at the active sites of the enzymes.
Addendum to: Determination of a new spring-flying species of the Pterourus glaucus complex (Papilionidae) in southern New England.
Creators: name: Pavulaan, Harry
Publisher: name: The International Lepidoptera Survey
Year: 2024
Subjects: Pterourus bjorkae

description: After description of Pterourus bjorkae (Pavulaan, 2024) it was subsequently decided to deposit the holotype (female) and allotype (male) in the McGuire Center for Lepidoptera and Biodiversity, Gainesville, Florida.  19 paratypes remain in the collection of the present author.  Paratypes in the collection of Alex Grkovich have been transferred to the collection of C. Howard Grisham, Huntsville, Alabama.  The holotype (female) bears a red label and the allotype (male) bears a blue label as shown below:
Bioaerosols, airborne particulate matter, and symptoms at BC Liquor Distribution stores
Creators: name: Kennedy, Susan
name: Copes, Ray
name: Brauer, Michael (Of University Of British Columbia)
name: Na, Sonia
name: Karlen, Barbara
name: Leung, Victor L. T.
Publisher: name: The University of British Columbia
Year: 2008

description: An investigation into workplace exposures linked to the use of glass breaking machinery in BC liquor stores and their possible impact on employee health.
Formation of healthy lifestyle among schoolchildren with overweight and obesity
Creators: name: Palladina, Oksana
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The problem of overweight and obesity in school children is considered. It is shown that the problem of child obesity underlie the development of many serious medical illness. It is introduced the analysis of publications on the problem of overweight and obesity in schoolchildren. It is defined methods for detection and possible non-pharmacological correction of the condition. The necessity of creating and putting into practice of long-term training programs to promote healthy lifestyle among schoolchildren are overweight or obese, to prevent the development of cardiovascular disease and other metabolic complications. Conceptually, it is determined the main directions of teaching and physical education students who are overweight and obese. It is shown that it is advisable to inform children and parents about the need to combine a balanced diet with exercise stress.
Design, synthesis and biological evaluation of 1-aryldonepezil analogues as anti-Alzheimer's disease agents
Creators: name: Luo, Jiao
name: Xu, Jing-Jing
name: Ren, Hui-Jun
name: Xu, Jin-Bu
name: Gao, Feng
name: Fang, Dong-Mei
name: Wan, Lin-Xi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Cell Biology
Molecular Biology
Neuroscience
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Information Systems not elsewhere classified
Mental Health

description: Aim: To design and synthesize a novel series of 1-aryldonepezil analogues. Materials & methods: The 1-aryldonepezil analogues were synthesized through palladium/PCy3-catalyzed Suzuki reaction and were evaluated for cholinesterase inhibitory activities and neuroprotective effects. In silico docking of the most effective compound was conducted. Results: The 4-tert-butylphenyl analogue exhibited good inhibitory potency against acetylcholinesterase and butyrylcholinesterase and had a favorable neuroprotective effect on H2O2-induced SH-SY5Y cell injury. Conclusion: The 4-tert-butylphenyl derivative is a promising lead compound for anti-Alzheimer's disease drug development. 19 1-aryldonepezil analogues were prepared by palladium-catalyzed Suzuki cross-coupling. The cholinesterase inhibitory activities and neuroprotective effects of these analogues were evaluated. 1-(4-tert-butylphenyl)aryldonepezil showed the most potential bioactivity. In silico docking experiments demonstrated the possible binding model. 1-(4-tert-butylphenyl)aryldonepezil is a promising lead compound for anti-Alzheimer's disease drug development.
Exploring the current advancements of quercetin nanoformulations alleviating respiratory diseases
Creators: name: Yeung, Stewart
name: Paudel, Keshav Raj
name: De Rubis, Gabriele
name: Williams, Kylie A.
name: Hansbro, Philip Michael
name: Dua, Kamal
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Exploring the current advancements of quercetin nanoformulations alleviating respiratory diseases
Comparison of economic activity leading U.S. sports leagues
Creators: name: Strikalenko, Eugen
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The main activities of the leading sports leagues were described. Sources of revenue and expenditure were identified. The economic performance of professional sports leagues of the United States of America was compared. In the course of the study of economic efficiency of the leading American sports leagues are defined payroll (expense commands on the salaries of players for each team, the total payroll in the League and the average payroll, respectively, for each of the American League. The largest estimates on wages, both in the League and in teams - in the National football League, the largest player's contract - in the Highest League baseball, the minimum wage in the National hockey League; the highest average wages, a greater percentage of athletes with a salary of more than 1 million. $ (82,85 %) in the National basketball Association were showed. This difference in the maximum income of the League and of average wages is due to several factors: the number of players in the team, the number of games in a season, and expenses on carrying out of competition and training activities.
Dark-colored Oncocyclus irises in Israel analyzed by AFLP, whole chloroplast genome sequencing and species distribution modeling
Creators: name: Volis, Sergei
name: Zhang, Yonghong
name: Deng, Tao
name: Yusupov, Ziyoviddin
Publisher: name: Brill Online
Year: 2022
Subjects: Ecology not elsewhere classified

description: The Haynei is one of seven species aggregates (clusters of species having similar flower morphology) recognized in section Oncocyclus of genus Iris. This aggregate, characterized by dark-colored flowers, is represented by six species in Israel and adjacent Jordan. There is, however, no knowledge of the genetic relationship of these species making verification of their taxonomic status impossible. We investigated genetic variation in this group using analysis of whole chloroplast genomes and amplified fragment length polymorphism (AFLP). We also used species distribution modeling (SDM) to predict species ranges under current climatic conditions. We found some population groups within the currently recognized species of section Oncocyclus to represent dramatically different genetic entities which devaluates a general trend of merging many previously recognized species of section Oncocyclus based on their flower morphology. Despite the importance of homoploid hybridization in this group's evolution and some apparently sporadically happening inter-specific gene flow, the main evolutionary forces in Oncocyclus appear to be vicariance and spatial isolation. Our findings suggest that some of the currently recognized species in section Oncocyclus need revision. A revision must be based on genetic analyses allowing the reconstruction of ancestry and recognition of the importance of vicariance and spatial isolation in the evolution of this group. The implications of the present findings for conservation are discussed.
Epigenetics and suicide: investigating altered H3K14ac unveiled differential expression in ADORA2A, B4GALT2 and MMP14
Creators: name: Arčan, Iris Šalamon
name: Kouter, Katarina
name: Zupanc, Tomaž
name: Paska, Alja Videtič
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health

description: Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to changes of chromatin (de)condensation and consequently gene expression. Materials & methods: Level of H3K14ac was studied with chromatin immunoprecipitation followed by high-throughput DNA sequencing. Genes were further validated with RT-qPCR; using hippocampal tissue. Results: We showed lowered H3K14ac levels in individuals who died by suicide. The genes ADORA2A, B4GALT2 and MMP14 showed differential expression in individuals who died by suicide. Identified genetic and protein interactions among genes show interactions with suicide-related genes. Conclusion: Further investigations of histone modifications in association with DNA methylation and miRNA are needed to expand our knowledge of the genes that could significantly contribute to suicide. Epigenetics importantly contributes to the development of mental disorders and suicidality. Post-translational modifications of the histone tail importantly contribute to the opening or closing of the chromatin. Hippocampus of 20 suicides and 20 control subjects were included in the study. H3K14ac level was investigated in hippocampus of suicides, compared with the controls. Chromatin immunoprecipitation followed by high-throughput DNA sequencing determined the level of H3K14ac. Genes ADORA2A, B4GALT2 and MMP14 were differentially expressed in suicides compared with controls. Lowered H3K14ac level was associated with lowered gene expressions of differentially expressed genes. ADORA2A has been studied in several neuropsychiatric pathologies. ADORA2A and B4GALT2 are in interaction with NTRK2 gene.
UNIVERSAL PRODUCT "AMARANT XXI" O`SIMLIGIDAN YOG` AJRATIB OLISH TEXNOLOGIYASI
Creators: name: Shoniyozov, B.K.
name: Qozoqboyev, S.
name: Qochqarov, I.R.
name: Komiljonov, O.
name: Toshtemirova, S.J.
Publisher: name: Zenodo
Year: 2024

description: AMARANT XXI o’simligini sho`rlangan yerlarning meliorativ holatini  yahshilash texnologiyasi joriy qilish orqali  tuproq meliorativ holatini  yahshilash hamda qimmatbaho va dorivor don bilan oziq-ovqat sanoatiga xom-ashyo etkazib berish, jaxon bozorida qimmatbaho hisoblangan skvalen saqlaydigan  moy olish, farmatsevtika va porfyumeriya sanoatini xom-ashyo bilan ta'minlash, chorvachilik uchun oziqa bazasini yaratishdan iborat. Eng qulay sharoit Amarant o`simligi organik va mineral o’g’itlar bilan o`g`itlagan holda urug`i tarkibidago skvalen moddasini foiz konsentratsiyasini  o’rganish.
An assessment of the health system impacts of direct-to-consumer advertising of prescription medicines (DTCA), volume 5 : predicting the welfare and cost consequences of direct-to-consumer prescription drug advertising
Creators: name: Morgan, Steve
Publisher: name: Centre for Health Services and Policy Research (CHSPR)
Year: 2014

description: Economic theory and historical experience indicates that the marketplace for ideas created by consumer directed drug advertisements would be imbalanced and biased. What is truly needed is investment in independent sources of evidence based educational programs that help consumers (not to mention medical professionals) to better understand the risks and benefits of treating disease with alternative drug and non-drug therapies.
Methodological foundations of healthy lifestyle
Creators: name: Muhamediarov, Nik
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The phenomenon of a healthy lifestyle is analyzed in terms of such methodological approaches as systemic, synergetic, personality-centered, hermeneutic and holistic ones. The pedagogical principles of harmony with nature, humanization and democratization, complexity and interdisciplinary integration, succession and continuity are defined. A conceptual idea of a healthy lifestyle is formulated including formation of cultural, social and economic reasons to preserve and strengthen the health of Ukrainians, consolidation of the efforts of teachers to develop a long-term educational technology for forming a healthy lifestyle, which will unite all periods of human life (pre-school, school, student, mature age), improvement of the health of people in the Ukrainian society, maintenance of optimum ability to work, improvement of the quality of life for healthy living and educating healthy children. The basic mechanisms of implementation of the conceptual idea are proposed.
Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action
Creators: name: Rayan, Seham A
name: George, Riham F
name: Mohamed, Nada M
name: Said, Mona F
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Aim: Over the last few decades, therapeutic needs have led to a search for safer COX-2 inhibitors with potential anti-inflammatory and analgesic activity. Materials & methods: A new series of oxazolone and imidazolone derivatives 3a–c and 4a–r were synthesized and evaluated as anti-inflammatory and analgesic agents. COX-1/COX-2 isozyme selectivity testing and molecular docking were performed. Results: All compounds showed good activities comparable to those of the reference, celecoxib. The most active compounds 3a, 4a, 4c, 4e and 4f showed promising gastric tolerability with an ulcer index lower than that of celecoxib. The molecular docking of p-methoxyphenyl derivative 4c showed alkyl interaction with the side pocket His75 of COX-2 and achieved the best anti-inflammatory activity, with a COX-2 selectivity index better than that of celecoxib. Novel oxazolone and imidazolone derivatives were designed and synthesized. The new compounds showed good analgesic and anti-inflammatory activities. The most active compounds showed good COX-2 selectivity. Compound 4c was the best anti-inflammatory agent. The selected compounds showed gastric tolerability. Molecular docking found that the scaffold of the tested derivatives showed very similar binding pattern with the main hydrophobic channel residues of both isoenzymes. The high activity of the derivative 4c was attributable to the additional alkyl interaction with the side pocket His75 of COX-2.
The essential characteristic of health preserving competence of physical education teacher
Creators: name: Ivaniy, Igor
Publisher: name: figshare
Year: 2013
Subjects: Education

description: It is grounded theoretical component of the essence of health-physical education teacher competence. Determine the relevance and unquestionable practical importance of this problem. Presents the basic concepts that define the essence of the competence of health-physical education teacher. Preserving the health of a competent teacher is seen as a component of physical culture of personality and professional competence. Determined that the health-competence is a manifestation of the teaching culture of health, the basis of social and educational maturity acquired during training and operations. Substantiated that the competence of health physical education teacher is a complex integrated education in personality structure specialist. School health expertise integrates professional and personal aspects, namely, causes the formation of the physical education teacher positions.
Covid-19 asorati sifatida yuzaga kelgan yuz-jagʻ suyaklari osteomielitini erta tashxislashda MSKT tekshiruvi afzalliklar
Creators: name: Asatov Shodiyor Qahramon o'g'li, Rahmonova Gulbahor Ergashevna
Publisher: name: Zenodo
Year: 2024

description: Dolzarbligi. Yuz –jag’ suyagi har xil sohasida joylashgan destruktiv o’zgarishlarni aniqlash uchun eng ichonichli tekshiruv metodi bu Multispiral kompyuter tomografiya hisoblanadi. Multispiral kompyuter tomografiya malumotlar boshqa rentgenologik tekshiruv metodlariga nisbatan suyak destruktsiyasini erta diagnostika qilish, asosan yuqori jag’ suyagidagi, yani yallig’lanish protsessining atrof suyak toqimalariga va g’alvirsimon suyak shilliq qavatiga tarqalishini aniqlab beradi.

Kalit so’zlar: Covid-19, osteomiyelit, sinusit, MSKT, yuqori jag’, destruktsiya.
Computer diagnostics of level of professional competence formation of future physical culture teachers in the biological disciplines study
Creators: name: Voitovskaya, Oksana
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The analysis of the level of professional competence formation of future physical culture teachers in the biological disciplines study was provided. The study involved 79 students. It is applied methods of teaching observation and experiment. The computer program of monitoring of professional competence of future teachers of physical education was described in the study of the biological sciences. Analyzed the results of 448 students questionnaire of the first and second year, studying at specialty "teacher of physical culture." Found that the results of the formative stages of the experiments show significant positive changes in the levels of formation of professional competence of students of the experimental group. Found that the increase in the number of students with high and medium level of formation of professional competence and reduced the number of students with low level of formation of professional competence.
Structure and state of the university of physical culture students’ professional-pedagogical motivation
Creators: name: Stepanchenko, Natalija
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The state and dynamics of the university of physical culture students’ motivation was determined. The complex of diagnostic methods was used to determine the level of professional-pedagogical motivation, which was directed on outlining motivation components and its development levels determination. The research involved 232 students. It was found that for the 1st year students the first place was obtained by the professional-cognitive interest, second by achievement motive and third by professional intention. For the 4th year students, the first place is possessed by professional cognitive interest, then followed by motives referred to professional and then – motives of achievement. The diagnostics have outlined absence of certain professional intentions. Also from first to fourth year of studies the tendency of increasing the amount of students interest of which is not connected either to physical culture, sports nor to pedagogical activity is followed.
Football as a professional sport, and the prospects for its development in Ukraine
Creators: name: Berezka, Sergey
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The aim of the study was to determine the features of the functioning of European football as a segment of the service industry, bringing economic, social and political effects. The features of professional sports in Ukraine by the example of football as an object of scientific analysis were considered. It is considered the features of the functioning of football. The study used methods of system analysis, analysis methods specific sources, methods comparison, and statistical methods. It is shown that a significant influence on the development of modern sport in particular football by processes of commercialization and professionalization. Found that football is the manufacturer of a wide range of services that bring significant economic, social and political impact of the subjects and has a high football information and entertainment value for the audience.
Navigating the Urban Maze: GIS technology and the blurring boundaries between digital and physical infrastructure
Creators: name: Meier, Philip
name: Newlands, Gemma
Publisher: name: Zenodo
Year: 2024

description: Introducing the progression of GIS technology and its varied applications, we motivate a debate on whether digital maps should be treated akin to physical public infrastructure, given their critical role in both private and public decision-making. Examining the risks and dependencies created by proprietary geodata services, we call for re-evaluating digital maps in the public utility and governance framework.
Characteristics of the physical heart trained and untrained students depending on the level of bioelements in the body
Creators: name: Reshetnjak, Olga
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The functional inspection of cardiac activity is conducted at 80 physically trained and untrained students, who have been surveyed about the maintenance of cadmium, potassium and calcium in an organism. The research of the element balance of students revealed that study of chemical elements in the organism of sportsmen was more satisfactory, than for the physically untrained students which showed the deficit of essential elements. The research of features of reaction of the cardiovascular system on the physical loading showed that physiological role of toxic cadmium for the state of the cardiovascular system was more expressed for sportsmen, than for the physically untrained students, though its content in an organism was within the limits of the existing norm. The physiological role toxic and essential elements for an action of the heart of sportsmen and the persons who are not going in for sports is revealed.
Hydro aerobics as means for physical state improvement of female students
Creators: name: Balamutova, Natalia
name: Babadganjan, V.V.
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The questions of organization and conducting studies were considered by using system of hydro aerobics exercises for improving physical training of female students. Sixty female students took part in the experiment. All the tested girls were divided into two groups, 30 persons each. The tested group of female students made aerobic exercises on the dry land according to a plan. The female students of experimental group made hydro aerobics exercises according to the programme. Several methods were used: anthropometry, control methods of the functional parameters of the body, testing of the physical training indicators, methods of mathematical statistics. The reliable positive improvements of cardiovascular and respiratory systems were in the experimental group of the girls. The effect of the reliable decrease of fat mass of the tested female students was exposed among anthropometrical characteristics.
Soles dermatoglyphics in the prognosis of sports endowment: differences of soles dermatoglyphics in sportsmen of different sport kinds
Creators: name: Serhiyenko, Leonid
name: Lyshevska, V.M.
Publisher: name: figshare
Year: 2013
Subjects: Education

description: The problem of determining associations between certain groups of sports and dermatoglyphics feet. The study involved 207 men, the general population (those who are not in sports), aged 17-19 years and 78 men highly skilled athletes. It is shown that as a criterion in the sports orientation of children and adolescents can be dermatoglyphics. The features of the structure of the foot dermatoglyphics in men of different sports specialties. There are informative signs dermatoglyphics thumb and feet, which can be recommended to assess the prospects of a particular athlete's motor activity. Among these are the types of finger patterns, combined account and certain dermatoglyphic phenotypes. It is proved that certain features of dermatoglyphics feet act as genetic markers in predicting propensity athletes to realize the potential of high specific energy pattern.
title: Neuartige Anodenkonzepte für Zink-Luft- und Lithium-Ionen-Batterien
Creators: name: Deckenbach, Daniel
Publisher: name: UNSPECIFIED
Year: 2024

description: In dieser Arbeit werden neuartige Anodenkonzepte für Zink-Luft und Lithium-Ionen-Batterien
als elektrochemische Energiespeicher für zukünftige Anforderungen in Hochleistungsanwendungen vorgestellt. Gegenstand des Promotionsvorhabens sind zum einen Zink-LuftBatterien als aufstrebende Technologie für eine sichere und nachhaltige Energiespeicherung
und zum anderen Lithium-Ionen-Batterien, die im Kontext der Elektromobilität besondere
Herausforderungen hinsichtlich einer schnellen Wiederaufladbarkeit zu lösen haben.
Mit der Forschung an einem Zinkoxid-Kohlenstoff-Verbundmaterial für alkalische Zink-LuftBatterien wurde eine neuartige Zinkelektrode entwickelt. Im Vergleich zu den bisher
verwendeten konventionellen Zinkanoden weist dieses innovative Material eine deutlich
verbesserte Speicherkapazität und Wiederaufladbarkeit auf. Die Forschungsergebnisse wurden
im Januar 2021 im Journal of Power Sources veröffentlicht. Durch eine detaillierte Analyse der
Grenzschicht zwischen Zinkelektrode und Elektrolyt konnten wichtige Erkenntnisse über die
Wiederaufladbarkeit von Zink-Luft-Batterien gewonnen werden. Dabei wurde der üblicherweise verwendete Zinküberschuss sowie der alkalische Elektrolyt als Schwachpunkte für die
Weiterentwicklung dieser Technologie identifiziert. Die Ergebnisse dieses Forschungsprojekts
wurden im April 2023 in Advanced Materials Interfaces veröffentlicht. Diese Erkenntnisse
führten zu einer Neubewertung des gesamten Zink-Luft-Batteriesystems mit dem Ziel, nicht
nur den Elektrolyten zu ersetzen, sondern eine Doppelnutzung zu ermöglichen, welche den
Einsatz einer Zinkanode überflüssig macht. Dies führte zur Entwicklung einer anodenfreien
Zink-Luft-Batterie, die im Februar 2024 erstmalig in Small vorgestellt wurde.
Die Forschungsarbeiten zu Lithium-Ionen-Batterien wurden im Rahmen des Forschungsvorhabens „PERSEUS: Aufbau einer skalierbaren Prozesstechnologie zur Herstellung von
binderfreien Elektroden für den Einsatz in Energiespeicheranwendungen basierend auf
funktionalisierten Carbon Nanohorns“ durchgeführt. Hierbei wurden binderfreie Elektroden
auf Basis von Kohlenstoffnanohörnern für den Einsatz in schnellladefähigen Energie-speichern
entwickelt. Die Ergebnisse sind in der Technischen Informationsbibliothek Hannover
veröffentlicht.