cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Distribution and dynamics of endoplasmic reticulum-plasma membrane junctions in pancreatic acinar and pancreatic cancer cells
Creators: name: Dingsdale, Hayley
Publisher: name: University of Liverpool Repository
Year: 2013

description: Endoplasmic reticulum (ER)-plasma membrane (PM) junctions are found in many different cell types. They function as important calcium (Ca2+) signalling structures, as sites of store-operated calcium entry (SOCE) and play many other crucial roles. Their distribution in polarised migrating pancreatic cancer cells, and in the polarised pancreatic acinar cells, was the subject of this investigation. In migrating cells, the specific spatial pattern of Ca2+ signalling has been shown to be of paramount importance, but is produced by an unknown mechanism that I aimed to investigate. In acinar cells, Ca2+ influx (via the SOCE complex) occurs basolaterally, whilst Ca2+ signals are generated apically, physically separating the two processes. The presence of the Ca2+ influx channel normally present in SOCE complexes (Orai1) in the apical region therefore, is a conundrum this investigation set out to untangle. I found that ER-PM junctions and SOCE complexes localise to the leading edge of migrating cells and are ideally positioned for Ca2+-dependent regulation of actin dynamics and focal adhesion turnover – processes crucial to migration. The appearance of junctions at the leading edge was saltatory, suggesting that it develops as a result of the formation of new junctions, not from a relocation of junctions from a more interior position. I also saw long distance translocation and dissolution of junctions in the retracting tails of migrating cells, in a manner similar to the dynamics of focal adhesions. In pancreatic acinar cells, PM-localised Orai1 was found on basal and lateral membranes, whilst apical Orai1 was found to be absent from the PM and instead in a structure just beneath it, co-localising with ER-located Ca2+-release channels.
Cheiracanthium mildei L. Koch 1864
Creators: name: Thaler, Konrad
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Miturgidae
Cheiracanthium
Cheiracanthium mildei

description: Cheiracanthium mildei L. Koch, 1864 (Clubionidae) (Abb. I) Mat.: Innsbruck, Pradl, Stiegenhaus, 19 (CoI!. Breuss) Okt. 2003, leg. Breuss. -Wien, Wohnhaus, 1 cf CTh 29. Juni 1999. 19 CTh 8. Juli 1999, leg. Christian. -Südtirol: Bozen, Stadtgebiet und Umgebung, I cf 79 1987-1996, leg. Bosin. Die von Südtirol (Meran) und Dalmatien erstbeschriebene Art ist holomediterran verbreitet, wobei ihre Nordgrenze lange durch den Südabfall der Alpen gebildet wurde (LESSERT 1910, SIMON 1932). Seither hat Ch. mi/dei sich enger an den Menschen angeschlossen und durch synanthrope Lebensweise ihrVerbreitungsgebiet auf die Neue Welt erweitert (BRYANT 1951, EDWARDS 1958). Auch in Mitteleuropa ist, noch wenig spektakulär, eine Verschiebung der Vorkommen nach Norden zu beobachten, siehe die Fundpunkte in Österreich (noch JÄGER 1995, KOMPOSCH 2002) und weitere, teilweise synanthrope, Fundmeldungen von Aargau (MAURER & HÄNGGI 1990), von Rhein und Main (Baden­ Württemberg, NÄHRIG et a!. 2003; Mainz, JÄGER 2000) und in Ungarn (SZINETAR 1992). Diese Erweiterung der ökologischen Einnischung scheint unter zwei Aspekten von unmittelbarer Bedeutung. So ist nicht auszuschließen, daß sich die Art als Lästling erweisen wird. Aus Nordamerika berichtete Bißverletzungen sprechen für diese Einstufung (SPIELMAN & LEVI 1970, KRINSKY 1987). Andrerseits gilt Ch. mi/dei als willkommener Antagonist für phytophage Arten in Gewächshäusern und Kulturen (CORRIGAN & BENNETT 1987, KASPI 2000, MANSOUR et a!. 1980 ab, 1995).
description: Published as part of Konrad Thaler, 2005, Fragmenta Faunistica Tirolensia - XVIII (Arachnida: Araneae; Insecta: Psocoptera, Strepsiptera, Megaloptera, Neuroptera, Raphidioptera, Mecoptera, Siphonaptera, Diptera: Mycetophiloidea), pp. 161-180 in Veröffentlichungen des Tiroler Landesmuseums Ferdinandeum 84 on page 162
The Influence of Plastic Barriers on Aerosol Infection Risk during Airport Security Checks
Creators: name: Zhu, Shengwei
name: Lin, Tong
name: Spengler, John D.
name: Cedeño Laurent, Jose Guillermo
name: Srebric, Jelena
Publisher: name: MDPI
Year: 2022
Subjects: ventilation
airport security check areas
plastic barriers
aerosol infection risk
computational fluid dynamics (CFD)

description: Plastic barriers physically separate queuing passengers in airport security check areas as a measure against aerosol transmission. However, this may create “canyons” that interfere with the existing ventilation design: potentially inhibiting airflow, concentrating exhaled viruses, and exacerbating aerosol transmission risk. Accordingly, this study investigated the transmission implications of installing plastic barriers in a security check area with computational fluid dynamics (CFD). Two air distribution schemes were modeled: one with linear air supply diffusers aligned vertically to (Case 1) and another with diffusers parallel with (Case 2) the orientation of partitions. The drift-flux model was used to calculate the spread of viral bioaerosols with 5 µm in diameter; then the Wells–Riley equation was applied to assess aerosol transmission risk for SARS-CoV-2. According to simulation results, in Case 1, installing plastic barriers resulted in relatively small changes in volume with a high infection risk of 1% or greater in the breathing zone within the first 25 min. However, in Case 2, using plastic barriers resulted in the continuous increase in this volume within the first 25 min while this volume was near zero if without plastic barriers. In conclusion, installing plastic barriers needs careful consideration because they do not reduce the risk of airborne SARS-CoV-2 transmission and might even exacerbate it without localized ventilation and air cleaning.
title: Reflection anisotropy spectroscopy as a potential new tool for linking macromolecular conformation to biological function
Creators: name: Convery, James
Publisher: name: University of Liverpool Repository
Year: 2013

description: The results reported in this thesis were obtained in a research programme that employed the surface sensitive optical probe reflection anisotropy spectroscopy (RAS) and related techniques to investigate conformational change associated with electron transfer processes in the protein cytochrome P450 reductase (CPR) adsorbed onto the Au(110)/electrode interface. It was found that controlling the adsorption of an ordered layer of CPR on the Au(110) surface is difficult and far more complex than first expected. In order to understand the adsorption process further an extensive investigation using quartz crystal microbalance with dissipation (QCM D) was carried out. The results of the QCM D experiments established that the conditions necessary for the adsorption of a monolayer of CPR are extremely sensitive to protein concentration and buffer pH. This was a crucial step in the research which allowed the preparation of adsorbed ordered monolayers of CPR on Au(110)/electrode interfaces. The RA spectral signatures of a monolayer and bilayer of CPR adsorbed on the Au(110) surface have been identified and are reported in this thesis. Using azimuthal dependent reflection anisotropy spectroscopy (ADRAS) it was shown that a monolayer of adsorbed CPR aligns along one of the principle axis of the Au(110) surface. RAS investigations of the effect of inducing electron transfer processes in an adsorbed monolayer of CPR by stepping the applied electrode potential reveal changes in RA spectral shape and intensity which may be associated with conformational events in the adsorbed CPR. The RA spectra produced as a function of applied potential show that the adsorption of a monolayer of CPR impedes the Au(110) surface reconstruction from a (13) to the anion induced (11) structures.
Aligning multiple neuroanatomical reference resources across species with Uberon
Creators: name: Mungall, Christopher J
Publisher: name: Zenodo
Year: 2022
Subjects: uberon
neuroanatomy
INCF
common-coordinate-system
invited

description: Presentation from INCF Assembly Workshop “Where was I? The problem of rigorously identifying placement of electrodes or other probes in the brain, for many species”. Held September 14, 2022 from 20:45-22:15 Central European Time . You can view the entire INCF assembly program here: https://neuroinformatics.incf.org/2022/program.
Cheiracanthium punctorium Villers 1789
Creators: name: Thaler, Konrad
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Miturgidae
Cheiracanthium
Cheiracanthium punctorium

description: Cheiracanthium punctorium (Villers, 1789) (Clubionidae) (Abb. 2-3, 7) Mat.: Mötz, Tiwag-Siedlung ca. 700 m, Waldrand, Vorgärten, in Wohnung, 19 CTh Sept. 2003, leg. Glatz. Identifikation nach SIMON (1932), WOLF (1991). Aus N-Tirol erst einmal genannt, "Waldgelände am Piburger See" ca. 900 m, 1Q in "etwas gelichteter Fichtenwald, Vaccinium myrtillus und Gras" (pALMGREN 1973, THALER 1997b). Der "Dornfinger" tritt am süd!. Abfall der Alpen (MAURER & HÄNGGI 1990, KOMPOSCH & STEINBERGER 1999) und im öst!. Vorland auf. Der isolierte inneralpine Nachweis erschien zunächst einer Bestätigung bedürftig, zumal aus Südtirol erst eine Angabe vorliegt, von Brixen (TRENKWALDER 1997). Verf. glaubt auch gegenwärtig nicht an Persistenz des Vorkommens, sondern vermutet eine rezente Areal-Expansion. Die Art gilt als eine der wenigen "Giftspinnen" Mitteleuropas, ihr Biß allerdings ohne "ernste" Folgen (MARETIC 1975).
description: Published as part of Konrad Thaler, 2005, Fragmenta Faunistica Tirolensia - XVIII (Arachnida: Araneae; Insecta: Psocoptera, Strepsiptera, Megaloptera, Neuroptera, Raphidioptera, Mecoptera, Siphonaptera, Diptera: Mycetophiloidea), pp. 161-180 in Veröffentlichungen des Tiroler Landesmuseums Ferdinandeum 84 on page 162
Analysis of Pneumatic Artificial Muscles and the Inelastic Braid Assumption
Creators: name: Chambers, Jonathan M.
name: Wereley, Norman M.
Publisher: name: MDPI
Year: 2022
Subjects: McKibben actuators
PAM
inelastic braid assumption
photogrammetry

description: Pneumatic artificial muscles (PAMs) are becoming an increasingly popular form of soft actuator due to their unique actuation characteristics. The creation of accurate PAM actuation models is important for their successful implementation. However, PAM studies often employ actuation models that use simplifying assumptions which make the models easier to formulate and use, but at the cost of reduced accuracy. One of the most commonly used assumptions, the inelastic braid assumption, suggests that the braid does not stretch, and therefore would not affect its geometry or actuation force. Although this assumption has often been cited as a likely source of model error, its use has persevered for decades due to researchers’ inability to directly measure the effects of braid elasticity. The recent development of a photogrammetric method to accurately measure PAM geometry now enables this analysis. This study seeks to assess the current default adoption of the inelastic braid assumption in PAM models by attempting to quantify the braid elasticity effects. This research finds that current models that use the inelastic braid assumption can underestimate PAM diameter by as much as 30%, and overestimate actuation force by as much as 70%. These results show that braid elasticity can have a substantial effect on the geometry and actuation force of PAMs, and demonstrates that the inelastic braid assumption may not be a suitable universal assumption for PAM modeling and analyses, especially when low-stiffness braid materials are used.
Bisection-based asymmetric MT2 computation: a higher precision calculator than existing symmetric methods
Creators: name: Lester, Christopher G.
name: Nachman, Benjamin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: An MT2 calculation algorithm is described. It is shown to achieve better precision than the fastest and most popular existing bisection-based methods. Most importantly, it is also the first algorithm to be able to reliably calculate asymmetric MT2 to machine-precision, at speeds comparable to the fastest commonly used symmetric calculators.
description: 13 pages, 6 figures. C++ implementation contained within the files submitted to the arXiv. v1: Original submission v2: typo corrections. v3: two new figures and more timing info, shorter title. v4: ancillary file modified to carry additional help text, v5: ancillary file made more portable, v6: fixing small typos in the text, v7: changes to anciliary file to permit PiPI package development
Reassessing the discovery potential of the $B \to K^{*} \ell^+\ell^-$ decays in the large-recoil region: SM challenges and BSM opportunities
Creators: name: Jäger, Sebastian
name: Camalich, Jorge Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We critically examine the potential to disentangle Standard Model (SM) and New Physics (NP) in $B \to K^* μ^+μ^-$ and $B\to K^* e^+ e^-$ decays, focusing on $(i)$ the LHCb anomaly, $(ii)$ the search for right-handed currents, and $(iii)$ lepton-universality violation. Restricting ourselves to the large-recoil region, we advocate a parameterisation of the hadronic matrix elements that separates model-independent information about nonperturbative QCD from the results of model calculations. We clarify how to estimate corrections to the heavy-quark limit that would generate a right-handed (virtual) photon in the $b\to sγ$ contribution to the decay. We then apply this approach to the discussion of various sets of observables of increasing theoretical cleanness. First, we show that angular observables in the optimized $P_i^{(\prime)}$ basis are, in general, not robust against the long-distance QCD effects. While a fit to data favours a NP contribution to the semileptonic operators of the type $δC_9\simeq-1.5$, this comes at a relatively small statistical significance of $\lesssim2 σ$, once power corrections are properly accounted for. Second, two of these observables, $P_1$ and $P_3^{CP}$ are particularly clean at very low $q^2$ and sensitive probes of right-handed quark currents. We discuss their potential to set stringent bounds on the Wilson coefficient $C_7^\prime$, especially using data of the electronic mode. Finally, in light of the recent hint of lepton-universality violation in $B^+\to K^+\ell\ell$, we introduce and investigate new lepton-universality observables involving angular observables of the muonic and electronic modes and their zero crossings, and show that, if the effect is of the size suggested by experiment, these can clearly distinguish between different NP explanations in terms of underlying semileptonic operators.
description: We recalculated the results with some updated theoretical input parameters which cause mild changes in some central values and a slight increase of the significance of tensions with the SM. Included new Table with full results with errors obtained using Gaussian distributions of the nuisance parameters. Some parts of the discussions have also been improved
Efficient Identification of Jiles–Atherton Model Parameters Using Space-Filling Designs and Genetic Algorithms
Creators: name: Khemani, Varun
name: Azarian, Michael H.
name: Pecht, Michael G.
Publisher: name: MDPI
Year: 2022
Subjects: genetic algorithm
Jiles-Atherton model
space-filling design

description: The Jiles–Atherton model is widespread in the hysteresis description of ferromagnetic, ferroelectric, magneto strictive, and piezoelectric materials. However, the determination of model parameters is not straightforward because the model involves numerical integration and the solving of ordinary differential equations, both of which are error prone. As a result, stochastic optimization techniques have been used to explore the vast ranges of these parameters in an effort to identify the parameter values that minimize the error differential between experimental and modelled hysteresis curves. Because of the time-consuming nature of these optimization techniques, this paper explores the design space of the parameters using a space-filling design. This design provides a narrower range of parameters to look at with optimization algorithms, thereby reducing the time required to identify the optimal Jiles–Atherton model parameters. This procedure can also be carried out without using expensive hysteresis measurement devices, provided the desired transformer’s secondary voltage is known.
Euophrys aperta Miller 1971
Creators: name: Thaler, Konrad
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Salticidae
Euophrys
Euophrys aperta

description: Euophrys aperta Miller, 1971 (Salticidae) (Abb. 4) Mat. Innsbruck, Technik, Ruderalgelände, I cf CTh 11.-25. Mai 1993, leg. Meyer. Bestimmung nach LOGUNOV & KRONESTEDT (2003) (sub Talavera a.). Euophrys aperta wurde erst spät erkannt, ist aber weit verbreitet, Belgien bis Baikal-See. Es handelt sich um eine eurosibirische Offenlandart, die in Mitteleuropa nur dispers auftritt, besonders (?) an Habitaten unter starkem menschlichem Einfluß, wie Bahndamm (Mainz, JÄGER 2000), aufgelassener Steinbruch (Namur, VANUYTVEN 1996), Bergwerkshalde (PEKAR 1999). In Österreich (allerdings mit Vorbehalt) bereits für Steiermark (JANTSCHER 1997, RUPP 1999) und Oberösterreich (ROTH 1999) genannt.
description: Published as part of Konrad Thaler, 2005, Fragmenta Faunistica Tirolensia - XVIII (Arachnida: Araneae; Insecta: Psocoptera, Strepsiptera, Megaloptera, Neuroptera, Raphidioptera, Mecoptera, Siphonaptera, Diptera: Mycetophiloidea), pp. 161-180 in Veröffentlichungen des Tiroler Landesmuseums Ferdinandeum 84 on page 162
Evaluation of SNPP and NOAA-20 VIIRS Datasets Using RadCalNet and Landsat 8/OLI Data
Creators: name: Jing, Xin
name: Uprety, Sirish
name: Liu, Tung-Chang
name: Zhang, Bin
name: Shao, Xi
Publisher: name: MDPI
Year: 2022
Subjects: RadCalNet
evaluation
SNPP
NOAA-20
VIIRS
Landsat 8

description: In this study, we used RVUS data from RadCalNet as a benchmark to verify the radiometric accuracy and stability of operational and reprocessed SNPP/VIIRS data and the accuracy of NOAA-20/VIIRS data, as well as to assess the efficiency of the SNPP/VIIRS reprocessing algorithm. In addition, to remove the uncertainty of the RVUS site itself, we used Landsat 8/OLI as another benchmark with which to validate the accuracy and stability of VIIRS data through the RUVS site. The radiometric biases of the operational and reprocessed SNPP VIIRS bands were within ±4% and ±2%, respectively, as compared with the RUVS site and OLI, except for the M10 and M11 bands. In particular, the biases of the M5 and M7 bands were reduced by ~2% in this study. NOAA-20 VIIRS, on the other hand, was consistently lower than SNPP by ~2 to ~4% for all the bands. For the equivalent bands, the drift differences between operational and reprocessed SNPP/VIIRS and OLI were no larger than 0.24%/year and 0.1%/year, respectively. The reprocessing algorithm of SNPP VIIRS efficiently improved the radiometric accuracy and stability of the SNPP/VIIRS dataset to meet its specifications.
Von Neumann Was Not a Quantum Bayesian
Creators: name: Stacey, Blake C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: Physics Education (physics.ed-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Wikipedia has claimed for over three years now that John von Neumann was the "first quantum Bayesian." In context, this reads as stating that von Neumann inaugurated QBism, the approach to quantum theory promoted by Fuchs, Mermin and Schack. This essay explores how such a claim is, historically speaking, unsupported.
description: 25 pages, written in response to 1 sentence on Wikipedia. v3: journal version, plus deleted scenes
title: Modelling HIF-1α dynamics within single cells and neurospheres
Creators: name: Leedale, Joseph
Publisher: name: University of Liverpool Repository
Year: 2014

description: HIF-1 (Hypoxia Inducible Factor-1) is an oxygen-regulated transcription factor that mediates the intracellular response to hypoxia in human cells, targeting specific genes that promote cell survival by inducing processes such as angiogenesis and glycolysis. The HIF-1 signalling pathway has been of considerable interest due to its role in mammalian development and in particular several pathologies such as ischemia and cancer. Low cellular oxygen levels are found in cancer due to the rapid proliferation of tumour cells distant to blood vessels (forming a hypoxic core) and the typically irregular vasculature is unable to properly perfuse the tumour. In the Centre for Cell Imaging at the University of Liverpool, time lapsed imaging in an oxygen-controlled environment has captured the transient dynamics of the oxygen regulated subunit of HIF-1, HIF-1α, and revealed heterogeneity between individual cells. The essential characteristics of this data are modelled with a system of differential equations describing the feedback inhibition between HIF-1α and the pathway’s effective oxygen sensors. This novel model was formulated by employing a minimalist approach initially, allowing us to use the rich variety of single-cell data to determine the structure of the feedback loop between two key pathway components. Once the central regulatory motif was identified, the model was expanded to include more complexity, including experimental measurements for model parameter values and additional system components. Oxygen plays an especially important role in the early stages of tumour formation. Measurements of oxygen within cells have been recorded in cultured spheres of neuroblastoma cells at different atmospheric conditions. This data is representative of the early development stages of an avascular tumour and a spatial oxygen-diffusion model was coupled with the single-cell HIF-1α model to describe the dynamics of HIF-1α across a developing tumour. This coupled model is used to study HIF-1α dynamics in the context of various oxygen-dependent cellular functions such as cell-cycle progression and apoptosis by integrating with modifications of published mathematical models.
Adversarial Machine Learning for NextG Covert Communications Using Multiple Antennas
Creators: name: Kim, Brian
name: Sagduyu, Yalin
name: Davaslioglu, Kemal
name: Erpek, Tugba
name: Ulukus, Sennur
Publisher: name: MDPI
Year: 2022
Subjects: deep learning
covert communications
signal classification
adversarial attack

description: This paper studies the privacy of wireless communications from an eavesdropper that employs a deep learning (DL) classifier to detect transmissions of interest. There exists one transmitter that transmits to its receiver in the presence of an eavesdropper. In the meantime, a cooperative jammer (CJ) with multiple antennas transmits carefully crafted adversarial perturbations over the air to fool the eavesdropper into classifying the received superposition of signals as noise. While generating the adversarial perturbation at the CJ, multiple antennas are utilized to improve the attack performance in terms of fooling the eavesdropper. Two main points are considered while exploiting the multiple antennas at the adversary, namely the power allocation among antennas and the utilization of channel diversity. To limit the impact on the bit error rate (BER) at the receiver, the CJ puts an upper bound on the strength of the perturbation signal. Performance results show that this adversarial perturbation causes the eavesdropper to misclassify the received signals as noise with a high probability while increasing the BER at the legitimate receiver only slightly. Furthermore, the adversarial perturbation is shown to become more effective when multiple antennas are utilized.
Categories with Complements
Creators: name: Uriagereka, Juan
Publisher: name: MDPI
Year: 2022
Subjects: lexical categories
functional categories
(external) merge
matrix syntax
Pauli group

description: Verbs and nouns gear θ-dependencies, Case, agreement, or construal relations. Building on Chomsky’s 1974 decomposition of such categories into ±N, ±V features, by translating said features into ±1, ±i scalars that allow for the construction of a vector space, this paper studies the possibility of organizing said features into 2 × 2 square matrices. In the system proposed to explore “head-complement” relations, operating on nouns yields a measurable/observable (Hermitian matrix), which in turn limits other potential combinations with abstract lexical categories. Functional/grammatical categories in the system deploy the same features, albeit organized differently in the matrix diagonal and off-diagonal. The algebraic result is a group with well-defined mathematical properties, which properly includes the Pauli group of standard use in quantum computation. In the system, the presumed difference between categories and interactions—here, in a context of the head-complement sort—reduces to whether the magnitude of the matrix eigenvalue is 1 or not, in the latter instance inducing asymmetric interactions.
Systematic curation of disease concept mappings in Mondo
Creators: name: Mungall, Christopher J
Publisher: name: Zenodo
Year: 2021
Subjects: mondo
invited
PistoiaAlliance
OWL
monarch-initiative
OBO
bio-ontologies
diseases
mapping

description: Numerous sources for disease definitions and data models currently exist, which include HPO, OMIM, SNOMED CT, ICD, PhenoDB, MedDRA, MedGen, ORDO, DO, GARD, etc; however, these sources partially overlap and sometimes conflict, making it difficult to know definitively how they relate to each other. This has resulted in a proliferation of mappings between disease entries in different resources; however mappings are problematic: collectively, they are expensive to create and maintain. Most importantly, the mappings lack completeness, accuracy, and precision; as a result, mapping calls are often inconsistent between resources. The UMLS provides intermediate concepts through which other resources can be mapped, but these mappings suffer from the same challenges: they are not guaranteed to be one-to-one, especially in areas with evolving disease concepts such as rare disease. In order to address the lack of a unified disease terminology that provides precise equivalences between disease concepts, we created Mondo, which provides a logic-based structure for unifying multiple disease resources. Mondo utilizes human curation assisted by a combination of logical, probabilistic and lexical methods to assist in curation and hone curation on difficult areas, together with fostering a broader community of disease resources committed to working together.
Dictyna civica Lucas 1850
Creators: name: Thaler, Konrad
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Dictynidae
Dictyna
Dictyna civica

description: Dictyna civica (Lucas, 1850) (Dictynidae) (Abb. 5--6, 8) Mat.: Innsbruck, Hauptbahnhof, an Fassaden, 69 CTh 1. Mai 2003, 19 CTh 17. Mai 2003. -Salzburg: Saalfelden, an Fassade, 1 cf 19 CTh 28. Okt. 2003, leg. HöUer. Die "Mauerspinne" ist eine südliche Art und in den Städten Mitteleuropas seit langem als Lästling etabliert, so Paris (DUMERIL 1850), Mainz (BRAUN 1952), Dresden (HERTEL 1968). Ihre persistenten Gespinste heben sich wegen anhaftenden Staubes schwärzlich an Fassaden ab, eine treffende Überschrift lautete "Maserung von Wänden durch Spinnen". Aus Österreich war zunächst nur ein Fundort in Kärnten aus dem Jahr 1989 verbürgt, doch wurden seither Vorkommen in Ostösterreich, Alpenvorland und Kärnten bekannt (THALER & KNOFLACH 1995, KOMPOSCH 2000, 2002). Dabei ist festzuhalten, daß sich die Artzugehörigkeit nicht allein aus der "Maserung" ergibt, sondern nach den speziellen Merkmalen der Kopulationsorgane festzustellen ist. Zumindest in Innsbruck hat einmal (2002) die einheimische, an Vegetation vorkommende Art D. pusilla Thorell, 1856 ein entsprechendes Schadbild hervorgerufen. Demnach istD. civica ein adventiver Neuzugang: eine frühe Meldung aus dem ländlichen Gschnitztal (Seehöhe 1200-1300 m) aus den Jahren vor 1955 erscheint wenig glaubhaft (THA­ LER 1993).
description: Published as part of Konrad Thaler, 2005, Fragmenta Faunistica Tirolensia - XVIII (Arachnida: Araneae; Insecta: Psocoptera, Strepsiptera, Megaloptera, Neuroptera, Raphidioptera, Mecoptera, Siphonaptera, Diptera: Mycetophiloidea), pp. 161-180 in Veröffentlichungen des Tiroler Landesmuseums Ferdinandeum 84 on page 163
Erlebnispädagogische Interventionen für Kinder mit ADHS: Sozialpädagogische Unterstützungsangebote im Schulkontext
Creators: name: Bordon, Salomé
Publisher: name: Hochschule Luzern – Soziale Arbeit
Year: 2024

description: In dieser Bachelorarbeit werden die Themenfelder ADHS und Erlebnispädagogik in einen Zusammenhang gebracht. Die Facetten einer ADHS-Diagnose werden erläutert. Es wird auf die psychosozialen Folgen und die Auswirkungen einer ADHS-Diagnose auf den Schulalltag eingegangen. Die Erlebnispädagogik wird definiert und wichtige erlebnispädagogische Modelle werden vorgestellt. In der Erlebnispädagogik werden Herausforderungen in der Natur als Gruppe überwunden und die daraus resultierenden Erlebnisse durch Reflexionsprozesse zu Erfahrungen und Erkenntnissen verarbeitet.

In dieser Arbeit bekommen Sozialpädagog*innen erlebnispädagogische Handlungsansätze aufgezeigt, welche die Integration von Kindern mit ADHS ins Schulsystem fördern. Basierend auf dem Ansatz der inklusiven Erlebnispädagogik werden erlebnispädagogische Interventionen dargelegt, die den Selbstwertaufbau und das Selbstvertrauen von Kindern mit ADHS fördern. Zudem wird die vielfältige Wirkung von Naturerfahrungen in der Erlebnispädagogik aufgezeigt.

Eine wichtige Erkenntnis ist, dass erlebnispädagogische Interventionen das Verständnis für die ADHS-Symptomatik bei allen Beteiligten fördert und helfen, die Stärken bei Primarschulkindern mit ADHS zu erkennen. Dabei werden Ansätze abgeleitet, wie die Sozialpädagogik im Schulkontext erlebnispädagogische Elemente implementieren könnte. Die positiven Effekte der Erlebnispädagogik für Kinder mit ADHS zeigen die Relevanz dieses Ansatzes für die Soziale Arbeit an Schulen auf.
description: + Code Diss LU: hslusa basa be + Fussnote: Bachelor-Arbeit, Hochschule Luzern – Soziale Arbeit, Studienrichtung Sozialarbeit, 2024 + NL-Code: NLLUHSA202409
Central Control for Optimized Herbaceous Feedstock Delivery to a Biorefinery from Satellite Storage Locations
Creators: name: Resop, Jonathan P.
name: Cundiff, John S.
name: Grisso, Robert D.
Publisher: name: MDPI
Year: 2022
Subjects: herbaceous feedback
spatial modeling
spatial analysis
biomass logistics
biomass load-out
biomass hauling
satellite storage locations

description: The delivery of herbaceous feedstock from satellite storage locations (SSLs) to a biorefinery or preprocessing depot is a logistics problem that must be optimized before a new bioenergy industry can be realized. Both load-out productivity, defined as the loading of 5 × 4 round bales into a 20-bale rack at the SSL, and truck productivity, defined as the hauling of bales from the SSLs to the biorefinery, must be maximized. Productivity (Mg/d) is maximized and cost (USD/Mg) is minimized when approximately the same number the loads is received each day. To achieve this, a central control model is proposed, where a feedstock manager at the biorefinery can dispatch a truck to any SSL where a load will be available when the truck arrives. Simulations of this central control model for different numbers of simultaneous load-out operations were performed using a database of potential production fields within a 50 km radius of a theoretical biorefinery in Gretna, VA. The minimum delivered cost (i.e., load-out plus truck) was achieved with nine load-outs and a fleet of eight trucks. The estimated cost was 11.24 and 11.62 USD/Mg of annual biorefinery capacity (assuming 24/7 operation over 48 wk/y for a total of approximately 150,000 Mg/y) for the load-out and truck, respectively. The two costs were approximately equal, reinforcing the desirability of a central control to maximize the productivity of these two key operations simultaneously.
title: Studies of RNF168 and CXCL5 expression by epithelial cell lines during RSV infection
Creators: name: Jeyatheswaran, Jonathan
Publisher: name: University of Liverpool Repository
Year: 2014

description: Background: During herpes simplex virus type 1 (HSV-1) infection, the protein ICP0 causes degradation of RNF168 during infection, preventing the ubiquitination of histones proteins and a subsequent DNA damage response to double strand breaks. Our laboratory has shown that during RSV infection in vitro, RSV replication as measured by RSV N gene expression increased considerably when SiRNA were used to knock down RNF168 gene. This suggests that RNF168 activity may be affected by RSV expression or act to limit RSV replication normally during infection as part of a host cell intrinsic antiviral defence. Identifying and understanding the mechanism by which this occurs may be useful in the development of future drug therapies for RSV. Aims: To investigate the effect of RSV infection, interferon beta stimulation and polyI:C on RNF168 expression. To investigate how the duration of RSV infection affects the concentration levels of CXCL5. Methods: A549 cells were infected with RSV in a 24-well plate. Cells were also stimulated with IFN-β and the TLR3 ligand polyI:C. Real-time PCR for RSV N gene expression and Sandwich ELISAs for IL-6 and IL-8 were carried out to provide evidence that samples have been infected. Western Blotting was carried out to measure RNF168 expression. A Sandwich ELISA was applied to measure the concentration levels of CXCL5. Results: At a MOI of 1:1, 4 hours RSV infection suggested that there was an increase in RNF168 expression. This increase was not statistically significant (p=0.13). At 24 hours after RSV infection, MOI 1:1 the level of RNF168 expression decreased in comparison to control but this decrease was not statistically significant (p=0.14). However, at a MOI of 0.025:1, 24 hours after infection, RNF168 expression increased in comparison to the control. This change was not significant (p=0.29). IFN-β stimulation for 4 hours suggested that higher concentrations of IFN-β increased RNF168 expression. This was not a significant change (p=0.17). IFN-β stimulation for 24 hours suggested that higher concentrations caused a decrease in RNF168 expression in comparison to the control (p=0.6 for 100ng/ml). An increase in CXCL5 concentration in infected samples was seen at 6 hours in comparison to control, which supports previous proteonomic data results.
A Study of Dynamics of the Tricomplex Polynomial $η^p+c$
Creators: name: Olivier-Parisé, Pierre
name: Rochon, Dominic
Publisher: name: arXiv
Year: 2014
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37F50, 32A30, 30G35, 00A69

description: In this article, we give the exact interval of the cross section of the so called Mandelbric set generated by the polynomial $z^3+c$ where $z$ and $c$ are complex numbers. Following that result, we show that the Mandelbric defined on the hyperbolic numbers $\mathbb{D}$ is a square with its center at the origin. Moreover, we define the Multibrot sets generated by a polynomial of the form $Q_{p,c}(η)=η^p+c$ ($p \in \mathbb{N}$ and $p \geq 2$) for tricomplex numbers. More precisely, we prove that the tricomplex Mandelbric has four principal slices instead of eight principal 3D slices that arise for the case of the tricomplex Mandelbrot set. Finally, we prove that one of these four slices is an octahedron.
title: Octupole collectivity in 220Rn and 224Ra
Creators: name: Gaffney, Liam P
Publisher: name: University of Liverpool Repository
Year: 2013

description: Collective properties of the radioactive nuclei 220Rn and 224Ra have been studied via Coulomb excitation of a 2.8 A.MeV radioactive ion beam (RIB) incident upon 60Ni, 112,114Cd and 120Sn targets. The experiments took place at the REX-ISOLDE RIB facility, CERN. De-excitation γ-ray yields following multiple-step Coulomb excitation were detected in coincidence with recoiling target nuclei in the Miniball spectrometer. For the first time, B(E3;3+ → 0+) values have been directly measured with a radioactive ion beam. In the process, 224Ra becomes the heaviest post-accelerated RIB to date at ISOLDE (with the possible exception of the quasi-stable 238U). The measurements presented in this thesis represent a tripling of the number of nuclei around Z ≃ 88 and N ≃ 134, for which direct measurements of the octupole collectivity have been performed. The only previous measurements being for the relatively long-lived 226Ra. The γ-ray yields, in conjunction with previously measured spectroscopic data, were used to determine electromagnetic matrix elements using the least-squares search code, Gosia. In total, nine E1, E2 and E3 matrix elements were measured in 220Rn (plus six upper limits) and 12 (plus four upper limits) in 224Ra. The measured B(E3; 3+ → 0+) values in 220Rn and 224Ra are 32±4 W.u. and 42±3 W.u., respectively. A new state has been observed at 937.8(8) keV in 220Rn and is proposed to be the 2+ member of the K = 2, γ-vibrational band. The results are interpreted in terms of the collectivity and deformation, and are compared with the predictions of self-consistent mean-field theory and cluster model calculations.
Isomonodromic deformation of q-difference equations and confluence
Creators: name: Dreyfus, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 39A13, 34M56

description: We study isomonodromic deformation of Fuchsian linear q-difference systems. Furthermore, we are looking of the behaviour of the Birkhoff connexion matrix when q goes to $1$. We use our results to study the convergence of the Birkhoff connexion matrix that appears in the definition of the q-analogue of the sixth Painlevé equation.
title: Conservatism, imperialism and appeasement: the political career of Douglas Hogg, first Viscount Hailsham 1922-38
Creators: name: Cooper, Christopher
Publisher: name: University of Liverpool Repository
Year: 2013

description: By using the political career of the leading Conservative Douglas Hogg, 1st Viscount Hailsham, as a prism, this thesis explores important aspects of inter-war British politics. Considering that Hailsham held key posts during the 1920s and 1930s, his career has attracted less historical coverage than one would expect. By charting his important role in the policy-making process, this study sheds light upon the major challenges facing Conservative leaders and enhances our understanding of British politics during this turbulent period. Hailsham helped shape the moderate form of Conservatism that asserted itself at this time and became intimately involved in formulating Britain’s imperial, defence and foreign policies. Hailsham’s contribution to the Conservatives’ response to the rise of the Labour Party during Britain’s newfound age of mass democracy emphasises the intricacies of inter-war Conservatism. Notwithstanding the overwhelmingly working class electorate, the Conservatives were the dominant party at the polls and this study demonstrates that Hailsham played no small part in the Conservatives’ highly successful inter-war appeal. By the end of the 1920s, he had assumed such a prominent position that a number of high-ranking Tories regarded him as Stanley Baldwin’s likely successor. During the 1930s, Hailsham confirmed that he was a committed imperialist. He was amongst those who defined Britain’s policy as the Empire was transformed into the Commonwealth. He also made important contributions to the interplay between the National Government’s foreign and defence policies. He was one of only a handful of ministers whose continued presence allowed them to make interventions in Britain’s disarmament, rearmament and appeasement policies during the era of the European dictators and the rise of militaristic Japan. Hailsham’s contribution is even more significant because he has strong claims to being the first cabinet minister to express disquiet over the mounting German menace.
Student nurses' experiences of remote learning during Covid-19 pandemic: A qualitative evidence synthesis
Creators: name: Giltenane, Martina
name: Dowling, Maura
Publisher: name: University of Limerick
Year: 2023
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: AimTo systematically synthesize undergraduate student nurses' experience of online, blended or distance learning during Covid-19 pandemic.DesignA qualitative evidence synthesis (QES).Review MethodsA QES. Themes were organized using the ‘best fit’ framework approach. Methodological limitations and confidence in the review findings were informed by GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research).Data SourcesQualitative literature from five databases including CINAHL, PubMed, Medline, Education Full Text (H.W. Wilson) and ERIC were searched from March 2020 to November 2021.ResultsNine qualitative and two mixed method studies were included in this ‘best fit’ framework using Chickering and Gamson's Seven Principles for Good Practice in Undergraduate Education. Importance of the social presence of the teacher through effective communication and interpersonal relationships is highlighted. Clinical placement and in-person practical skills training are needed for effective nursing education.ConclusionsThis review highlighted that online content can be developed into efficient and high-quality learner-centred education within blended undergraduate nursing programmes incorporating essential face-to-face and practical components. Various supporting measures are required for both students and faculty. We suggest an adaptation of a ‘Blending with Purpose: The Multimodal Model’ with key considerations for undergraduate nursing programmes where pedagogical objectives and activities drive the approaches to achieve intended learning outcomes and student satisfaction.Implications for the ProfessionWell-designed online programmes using digital tools that support interaction and teamwork are required for undergraduate nursing education.ImpactBlended learning approaches offer more flexibility than online learning alone which leads to improved student engagement.Clinical placement and in-person practical skills training are needed for effective nursing education.Reporting Method
‘Enhancing transparency in reporting the synthesis of qualitative research’ (ENTREQ) for QES.No Patient or Public Contribution
title: Feminist historiography and the reconceptualisation of historical time
Creators: name: Browne, Victoria
Publisher: name: University of Liverpool Repository
Year: 2013

description: This thesis conducts a reconceptualisation of historical time as a means of reorienting feminist historiography and changing the ways that we construct and approach histories of feminism. Various feminist theorists have argued that feminist theory requires a multilinear, multidirectional model of historical time, to enable productive encounters and exchanges between past and present feminisms, and account for the coexistence of parallel, intersecting feminist trajectories. This is particularly crucial in light of the continuing dominance of the phasic ‘wave’ model of feminist history, which is bound to notions of linear succession and teleological progress, and severely curtails the ways in which diverse feminist histories can be mapped, understood and related to one another. However, whilst alternative, multilinear, multidirectional notions of historical time have been mooted, there is rarely any clarity or elaboration on what exactly what this might mean or how it might work. This, I suggest, is because ‘historical time’ is itself an under-investigated and under-articulated concept. My contribution in this thesis, therefore, is to offer a detailed study of historical time, which makes sense of the idea that historical time is multilinear and multidirectional. In the course of this investigation, I develop a ‘polytemporal’ model of historical time, arguing that historical time is generated through a mix of different temporalities and fields of time, including the ‘time of the trace’, ‘narrative time’, ‘calendar time’ and ‘generational time’. Analysing each of these ‘times’ in turn, the thesis offers a thorough and internally complex account of historical time, demonstrating how thinking history ‘polytemporally’ can work, and how historical time can be understood as multilinear and multidirectional. Further, it offers concrete suggestions as to how this reconceptualised model can translate into a more nuanced and effective feminist historiographical practice, which opens up conversations between past and present feminisms in order to positively transform our presents and futures.
Yosemite Project Webinar: LinkML - A Linked Open Data Modeling Language
Creators: name: Mungall, Christopher J
name: Solbrig, Harold
Publisher: name: Zenodo
Year: 2021
Subjects: linked-data
linkml
keynote
YosemiteSummit
RDF
semantic-web
healthcare

description: LinkML is a modeling language and collection of tools that joins the
 data processing world with the semantic, making it possible for
 developers to continue to employ tools such as JSON, YAML, SQL,
 spreadsheets, etc., while _directly_ working with RDF and ontology based
 semantics. LinkML leverages and integrates technologies such as
 JSON-LD, Knowledge Graphs, RDF and Shape Expressions (ShEx), and
 provides an environment where semantics and data are seamlessly
 integrated and structural and representational transformations between
 communities can be based on the combination of RDF and ontology.

 Why LinkML? Twenty years ago, Tim Berners-Lee coined the term "The
 Semantic Web" in a seminal article in Scientific American. While it is
 heartening to see how much of his vision has been realized, gaps still
 remain. Berners-Lee's vision included the notion that the "Semantic Web
 is not a separate Web but an _extension_ of the current one, in which
 information is given well-defined meaning...". While progress has been
 made in some areas (e.g. schema.org), the world of data and the world of
 semantics still exist in separate spaces. While tools and techniques
 exist to _transform_ (lift) data into the RDF space, to date these
 environments have been separate. LinkML helps to bridge this gap.

 This webinar provides a short introduction to the LinkML modeling
 language and tools: how it came to be, what it can be used for today,
 how it is being used in biomedical research, and where the developers
 intend to take it in the future.

 ABOUT THE SPEAKERS

 Harold Solbrig is an active contributor to healthcare information
 modeling, semantics and standards-based information exchange for 40+
 years. He has served in multiple roles in the ISO, W3C, HL7 and other
 standards communities. He has a master's degree in Software Engineering
 from Oxford University and is an assistant professor at Johns Hopkins
 University.

 Chris Mungall is Department Head of Biosystems Data Science at Lawrence
 Berkeley National Laboratory, working on the application of
 computational techniques to problems life sciences of relevance to the
 health of humans and the health of the planet. His main interest is the
 application of artificial intelligence, knowledge-based methods, and
 bio-curation to advance our understanding of the interconnected role of
 genes and genetic mechanisms in key biological processes.
fast-resolve: Fast Bayesian Radio Interferometric Imaging
Creators: name: Roth, Jakob
name: Frank, Philipp
name: Bester, Hertzog Landman
name: Smirnov, Oleg M.
name: Westermann, Rüdiger
name: Enßlin, Torsten
Publisher: name: Zenodo
Year: 2024

description: Reconstruction results of fast-resolve from the publication  "fast-resolve: Fast Bayesian Radio Interferometric Imaging". All files are in the fits format and have flux units of mJy/arcsec^2.