cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Studies on a double-stranded RNA-binding zinc finger protein
Creators: name: Finerty, Patrick Joseph
Publisher: name: University of Utah
Year: 2012
Subjects: dsRNA
Xenopus

description: Proteins containing C 2 H 2 type zinc finger motifs are perhaps the largest class of nucleic acid-binding proteins found in nature. This dissertation describes studies on a novel zinc finger protein, dsRBP-ZFa, isolated by screening a Xenopus cDNA expression library with dsRNA. The protein consists of a basic N-terminal region containing seven C 2 H 2 zinc finger motifs and an acidic C-terminal region that is not required for binding. The last four zinc finger motifs, and the linkers that join them, are nearly identical repeats, while the first three motifs and their linkers are each unique.  I show that dsRBP-ZFa binds dsRNA and RNA-DNA hybrids with nanomolar dissociation constants and in a sequence independent manner. Additionally, ssRNA and DNA fail to compete for binding suggesting that dsRBP-ZFa prefers to bind an A-form helix. Studies using fragments of dsRBP-ZFa encompassing the three N-terminal, unique zinc finger motifs, and another encompassing the last three of the nearly identically motifs, show that these have binding properties similar to the full-length protein.  I have conducted in situ mRNA hybridization experiments to investigate the expression pattern of dsRBP-ZFa mRNA in Xenopus embryos. These experiments revealed that dsRBP-ZFa mRNA is broadly expressed spatially and temporally within the Xenopus nervous system. Using western analyses, I also show that dsRBP-ZFa protein is primarily localized to the nucleus of stage 6 Xenopus oocytes and is present in Xenopus eggs.  While other proteins have been shown to bind dsRNA, dsRBP-ZFa is the first example of a zinc finger protein with this activity. Possible biological roles for dsRBP-ZFa and experiments to elucidate these are discussed.
Pectinosoma Arrow 1913
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Melolonthidae
Pectinosoma

description: PECTINOSOMA Arrow, 1913
Pectinosoma Arrow 1913b: 430
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 113, DOI: 10.5281/zenodo.3678492
Paulosawaya variolosa
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Paulosawaya
Paulosawaya variolosa

description: Paulosawaya variolosa (Burmeister, 1855)
Amphicrania variolosa Burmeister 1855: 28 (“Guianas,” Brazil)
Distribution. “Guianas”: Burmeister 1855: 28 (as Amphicrania variolosa); Dalla Torre 1913: 322 (as Clavipalpus variolosus); Blackwelder 1944: 229 (as Clavipalpus variolosus); Evans and Smith 2009: 225 (as Clavipalpus variolosus). Brazil: Burmeister 1855: 28 (as Amphicrania variolosa).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 113, DOI: 10.5281/zenodo.3678492
title:  Funzione sociale della proprietà e disciplina dei beni
Creators: name: Iannarelli, Antonio
Publisher: name: Roma TrE-Press
Year: 2017

description: Il saggio analizza sul piano storico il richiamo alla “funzione sociale” della proprietà  nella cultura e nella legislazione europea. Nel secolo XIX, dopo l’avvento del code Napoleon, l’attenzione della cultura economica e giuridica  si è concentrata sulla proprietà intellettuale, per cui si è posto l’accento sull’attività produttiva come effettiva giustificazione dell’appropriazione privata. La critica al modello dell’individualismo possessivo è emersa in Europa attraverso la riflessione e la ricerca sia dei Germanisti sia della Scuola Storica dell’economia in conflitto con il nascente socialismo e marxismo. Tuttavia, solo alla fine del secolo XIX, la crisi sociale ha portato alla “socializzazione del diritto” e alla affermazione della “funzione sociale” della proprietà. Di qui il passaggio dai Codici alle Costituzioni. Il saggio, infine,  illustra l’attuazione della funzione sociale  di cui parla l’art.42 Cost. intervenuta nel periodo storico dominato dal welfearismo e poi dall’ attuale neoliberale e segnala i profondi  mutamenti  in atto  nel diritto privato.
description: La funzione sociale nel diritto privato tra XX e XXI secolo
A new benzophenone, and the antiplasmodial activities of the constituents of Securidaca longipedunculata fresen (Polygalaceae)
Creators: name: Ochora, Douglas O.
name: Kakudidi, Esezah
name: Namukobe, Jane
name: Heydenreich, Matthias
name: Coghi, Paolo
name: Yang, Li Jun
name: Mwakio, Edwin W.
name: Andagalu, Ben
name: Roth, Amanda
name: Akala, Hoseah M.
name: Wong, Vincent K. W.
name: Yenesew, Abiy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: Hematology
subject: Plant Biology

description: Extracts from Securidaca longipedunculata showed antiplasmodial activities against reference clones and clinical isolates using SYBR Green I method. A new benzophenone, 2,3,4,5-tetramethoxybenzophenone (1) was isolated and characterized along with seven known compounds: 4-hydroxy-2,3-dimethoxybenzophenone (2); 3-hydroxy-5-methoxybiphenyl (3), methyl-2-hydroxy-6-methoxybenzoate (4), benzyl-2-hydroxy-6-methoxybenzoate (5), 2-hydroxy-6-methoxybenzoic acid (6), 2,4,5-trimethoxybenzophenone (7) and 2-methoxy-3,4-methylenedioxybenzophenone (8). Compounds 1 and 2 showed ex vivo antiplasmodial activities (IC50 28.8 μM and 18.6 μM, respectively); while 5 and 8 showed in vivo activities (IC50 19.7 μM and 14.5 μM, respectively) against D6 strain. In a cytotoxicity assay, all the extracts (with an exception of the MeOH extract of the leaves) and pure compounds were not toxic to the normal LO2 and BEAS cell-lines, while the methanol roots extract (IC50 66.4 µg/mL against A549, and 77.4 µg/mL against HepG2), compounds 6 (IC50 22.2 µM against A549) and 7 (IC50 45.2 µM against HepG2) were weakly active against cancerous cell-lines.
Brief an Gottfried Kirch
Creators: name: Schultz, Gottfried
Publisher: name: [s.n.]
Year: 1683

description: von Gottfried Schultz
description: Mit rotem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Brief an Gottfried Kirch
Creators: name: Schultz, Gottfried
Publisher: name: [s.n.]
Year: 1681

description: von Gottfried Schultz
description: Mit schwarzem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
Sonnenfleckenzeichnung Nr. 22956.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.12.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Auslandsaufenthalte als Instrument der Internationalisierungsarbeit in der beruflichen Bildung Möglichkeiten und Grenzen einer Mobilitätspädagogik
Creators: name: Will, Britta
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 370 Education

description: Forschungsbasierte Erkenntnisse darüber, wie berufliche Schulen die umfangreichen Aufgaben der Internationalisierungsarbeit in der Praxis organisieren oder wie sich die verantwortlichen Lehr- und Ausbildungsfachkräfte professionalisieren, gibt es bisher nicht. Das Dissertationsprojekt widmet sich dieser Forschungslücke und untersucht im Fokus des Förderprogramms Erasmus Plus in zwei perspektivischen Studien Aufgaben und Anforderungen aber auch verfolgte Umsetzungsstrategien und Handlungskonzepte des schulischen Bildungspersonals an beruflichen Schulen.
Experiences of Japanese American mixed race young adults: a study of identity formation
Creators: name: Doi, Shelley Michiye
Publisher: name: University of Utah
Year: 2012
Subjects: Japanese Americans
Ethnicity
Race
Racially mixed people

description: This study examines the experiences of Japanese American mixed race young adults and the effects that being mixed race has had on their identity formation. Specifically, it addresses how being mixed race affected other aspects of their lives, such as family, social relationships, school, and self-esteem. Using a qualitative study, seven mixed-race young adults were asked to answer a series of questions in a semi-structured interview. The results of the study indicated that students did not encounter significant health or emotional setbacks due to their mixed race identity. Rather, respondents voiced their unique experiences and showed that over time, they have come to view their mixed race heritage as a positive aspect of their lives.
STUDYING THE INFLUENCE OF THE ECOLOGICAL FACTORS ON THE PARASITOLOGICAL SITUATION IN FISH FARMING FACILITIES
Creators: name: Azerbaijan Journal Of Agrarian Studies
name: Suleymanova, Afet
Publisher: name: figshare
Year: 2020
Subjects: subject: 70302 Agronomy
subject: FOS: Agriculture, forestry and fisheries
subject: Parasitology
subject: 70404 Fish Pests and Diseases
subject: 70403 Fisheries Management

description: In 2014–2018 we studied the influence of environmental factors on the prevalence of diseases among fish grown in fish farms. Laboratory analysis of water bodies was carried out in order to determine biotic and abiotic factors (water temperature, pH level of water, the amount of oxygen dissolved in water, physico-chemical parameters, etc.), given the negative impact of water content on the spread of diseases. The occurrence of diseases in fish is due to the prevalence of parasite pathogens, poor nutrition, poor-quality feed, violation of the biochemical properties of water, planting density, etc. A close relationship with environmental factors was identified. The whole set of factors affects the fish, causing them stressful conditions that lead to diseases.
Sonnenfleckenzeichnung Nr. 22964.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.12.1968, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
From shoeboxes to shared spaces: participatory cultural heritage via digital platforms
Creators: name: Liew, Chern Li
name: Goulding, Anne
name: Nichol, Max
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Moves towards a post-custodial, participatory paradigm have been well-documented in the cultural heritage sector. The capacity for individuals to contribute to community archives is significant, given their emphasis on representing the experiences of those hidden, ignored, underrepresented or misrepresented by mainstream cultural heritage institutions. Digital platforms offer affordances that can be utilised to encourage the collecting, curating and sharing of collective memories. While there are analyses of individual projects in using technologies for these aims, collective analyses of such practices remain scant in the scholarly literature. This research examines a purposefully selected sample of projects that feature participatory cultural heritage practices and offers a collective analysis of their objectives and motivations, the varying levels of engagement, the technology-mediated participatory activities supported, and how the projects are resourced and sustained. The findings indicate that the enabling of participation through digital platforms vary in nature, depth and extent, and a spectrum approach can be a useful way of conceptualising and envisaging the various levels of engagement in participatory cultural heritage. The collective analysis shows that when projects are designed with a human-centred computing focus and a community-oriented foundation, there is evidence of deeper engagement and sustained participation.
Identification of optimal target sequences for antisense-, ribozyme-, and decoy-mediated gene inhibition
Creators: name: Chen, Zhidong
Publisher: name: University of Utah
Year: 2012
Subjects: Nucleotide sequence
Gene expression

description: Antisense oligonucleotides, ribozymes, and transcription factor decoys are nucleic acid based agents. They inhibit target gene expression in a sequence-specific manner, and therefore, have great therapeutic potential. Currently, a relatively effective antisense, ribozyme, or decoy sequence is identified by testing the inhibitory activity of a series of sequences individually. Because the number of potential sequences that need to be tested is much greater than the number of sequences that can be, or is actually, tested individually, it is unlikely that the most effective sequences are identified. Due to the lack of suitable means to identify optimal or effective sequences against specific genes, it is not uncommon that a chosen sequence fails to inhibit or poorly inhibits the expression of a target gene. In this dissertation, I describe the development of a library approach for the identification of optimal antisense, ribozyme, and decoy sequences against the expression of specific genes. For this approach, libraries of antisense RNAs, ribozymes, and decoys with distinctive nucleotide sequences are derived directly from a target gene. Screening these so-called directed libraries in target cells allows the identification of the antisense, ribozyme, and decoy sequences that can ablate the expression of the target gene. I demonstrate the effectiveness of this approach by identifying the optimal antisense, ribozyme, and decoy sequences against the expression of lacZ' gene in Escherichia coli. This approach should be generally applicable for the identification of optimal antisense, ribozyme, and decoy sequences against any gene of interest.
Plectris Le Peletier and Serville 1828
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Melolonthidae
Plectris

description: PLECTRIS Le Peletier and Serville, 1828
Plectris Le Peletier and Serville 1828: 369
Key. Frey 1967
Catalogue. Frey 1974a
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 113, DOI: 10.5281/zenodo.3678492
Nasutuceratops Titusi, a new basal centrosaurine dinosaur (Ornithischia: Ceratopsidae) from the upper cretaceous Kaiparowits Formation, Southern Utah
Creators: name: Lund, Eric Karl
Publisher: name: University of Utah
Year: 2012
Subjects: Centrosaurinae
Kaiparowits formation
Western interior basin
Nasutuceratops titusi
Ceratopsidae

description: Remains of a previously unknown horned dinosaur were recently recovered from the Upper Cretaceous (Campanian) Kaiparowits Formation of Grand Staircase-Escalante National Monument, southern Utah. These exceptionally preserved materials, including a nearly complete skull with multiple postcranial elements, represent a new genus and species of centrosaurine ceratopsid dinosaur, Nasutuceratops titusi n. gen. et n. sp. The new Utah taxon is placed within Centrosaurinae on the basis of multiple synapomorphies, including delta-shaped rostral; subcircular, hypertrophied narial region; thin, pronounced premaxillary septum; narial spine composed of processes from nasal and premaxilla;  expanded and thickened ventral angle on premaxilla; and subrectangular, stepped squamosal. Autapomorhies of this taxon include ectonaris comprises 75% of preorbital skull length; nasals pneumatic; premaxilla-maxilla contact hyper-robust; double faceted, medially directed flange on maxilla contributing to short hard palette; and supraorbital horncores rostrolaterally directed, rostrally curved, torsionally twisted, and relatively enormous. A phylogenetic analysis of Centrosaurinae places Nasutuceratops as the sister  taxon to Avaceratops lammersi from the late Campanian of Montana. Nasutuceratops titusi provides insights into the base of Centrosaurinae and suggests the existence of a previously unknown clade of short-snouted, long-horned centrosaurines in the southern Western Interior Basin (WIB) of North America. Nasutuceratops also provides strong support for hypothesis of dinosaur provinciality in late Campanian WIB.
Fotografische Sonnenaufnahme und zugehörige Zeichnung, unnummeriert.
Fotoabzug und durchgepauste Zeichnung der Aufnahme von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.10.1968, fotografiert von John S. Korintus
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Der Abzug ist auf der Rückseite mit genauen Angaben versehen. Flecken und Fackelflächen sind auf das Pauspapier übertragen. Im Jahresbericht für das vorliegende Jahr ist John S. Korintus nicht erwähnt
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.08.1968, erstellt von Emilia Tifrea, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Natural metabolites from the soft coral Nephthea sp. as potential SARS-CoV-2 main protease inhibitors
Creators: name: Abdelhafez, Omnia Hesham
name: Fahim, John Refaat
name: Mustafa, Muhamad
name: AboulMagd, Asmaa M.
name: Desoukey, Samar Yehia
name: Hayallah, Alaa M.
name: Kamel, Mohamed Salah
name: Abdelmohsen, Usama Ramadan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Hematology

description: The ongoing spread of SARS-CoV-2 has created a growing need to develop effective antiviral treatments; therefore, this work was undertaken to delve into the natural metabolites of the Red Sea soft coral Nephthea sp. (family Nephtheidae) as a source of potential anti-COVID-19 agents. Overall, a total of 14 structurally diverse minor constituents were isolated and identified from the petroleum ether fraction of Nephthea sp. The characterised compounds were screened and compared for their inhibitory potential against SARS-CoV-2 main protease (Mpro) using Autodock Vina and MOE software. Interestingly, most compounds were able to bind effectively to the active site of Mpro, of which nephthoside monoacetate (1); an acylated tetraprenyltoluquinol glycoside, exhibited the highest binding capacity in both software with comparable interaction energies to the ligand N3 and moderately acceptable drug-likeness properties, which drew attention to the relevance of marine-derived metabolites from Nephthea sp., particularly compound (1), to develop potential SARS-CoV-2 protease inhibitors.
Great Salt Lake energy production center.
Creators: name: Cracroft, Corey S
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: Designs
subject: Plans

description: From the Program: "The Sustainable Energy Production Center will have three major functions: energy production, research and development, and public education. The combination of these components will make the center a valuable place for the world energy community. It will provide electricity for the growing community near the Oquirrh Mountains, assist in the  technological advancement of clean power production, and educate the public about sustainable energy. The center will become an advocate for sustainable energy causes."
First report on phytochemical investigation, antioxidant and antidiabetic activities of Helianthemum getulum
Creators: name: Terfassi, Siham
name: Dauvergne, Xavier
name: Cérantola, Stéphane
name: Lemoine, Clément
name: Bensouici, Chawki
name: Fadila, Benayache
name: Christian, Magné
name: Marchioni, Eric
name: Benayache, Samir
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: A new flavonoid, 5,7,2′,4′,5′-pentahydroxyflavone 3-O-β-D-galactopyranoside (12) and twelve known derivatives: an aryltetralin-lignan (3), seven flavonoids (4-5, 7-10, 13) and four phenolic acids (1-2, 6, 11) have been isolated from the aerial parts of Helianthemum getulum Pomel. (Cistaceae family) an endemic species to the septentrional Sahara that is being studied for the first time. Structure elucidation of the isolated compounds was established by means of spectroscopic methods especially NMR and Mass Spectrometry. In vitro antioxidant (DPPH, ABTS, GOR and CUPRAC assays) and antidiabetic (micro-dilution method) activities of the crude extract, fractions and isolated compounds were performed. The new flavonol (12) and Compounds (2, 3, 7, 9) were found to be the most active, some of them exhibiting better activity than the antioxidant standards. Compounds 7, 9 and 3 showed higher α-glucosidase inhibitory activity compared to standard acarbose (IC50= 2.70 ± 0.03 µM, 3.09 ± 0.03 µM, 37.28 ± 1.20 µM and 275.43 ± 1.59 µM, respectively).
‘I’m still the master of the machine.’ Internet users’ awareness of algorithmic decision-making and their perception of its effect on their autonomy
Creators: name: Dogruel, Leyla
name: Facciorusso, Dominique
name: Stark, Birgit
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Algorithms are an integral part of our everyday lives and shape the selection and presentation of information and communication on the internet. At the same time, media users are faced with a lack of control and transparency when interacting with these systems because algorithms largely remain black boxes to end users. Relying on the notion that algorithms are socio-technical systems that comprise both technical and human components, this paper examines internet users’ awareness of algorithms in different areas of internet use and inquires into users’ perceptions of the impact of algorithms on their autonomy when interacting online. Empirically, we rely on qualitative interviews with 30 German internet users. Findings indicate that users in general are aware of algorithms operating in a wide range of applications and demonstrate a basic understanding of how these systems work. In line with the third-person effect, users perceive algorithms to have a stronger impact on others’ internet use than on their own. Further, users’ awareness of algorithms was found to be closely related to their perceived autonomy. When users feel in control of their interactions online, they are less aware of the impact of algorithms governing their interactions. Based on these results, we discuss the implications for transparency measures in algorithm regulation.
Antimycobacterial activity of Achyrocline flaccida (Asteraceae) aqueous extract from Southern Brazil
Creators: name: Machado, Vanessa Schopf
name: Verdi, Camila Marina
name: Rossi, Grazielle Guidolin
name: de Souza, Larissa Ilha
name: Teixeira, Cristiane Antunes
name: Machado, Marina Lopes
name: da Silveira, Tássia Limana
name: Sagrillo, Michele Rorato
name: Machado, Alencar Kolinski
name: Dornelles, Rafaela Castro
name: Campos, Marli Matiko
name: Rodrigues, Eliseu
name: Emanuelli, Tatiana
name: Somacal, Sabrina
name: Santos, Roberto Christ Vianna
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Achyrocline flaccida aqueous extract was obtained by macerating wildflowers. The phytochemical profile present in the A. flaccida aqueous extract was elucidated by HPLC-ESI-MS/MS. Toxicity was evaluated in vitro by comet assay in peripheral blood mononuclear cells (PBMCs) and in vivo using Caenorhabditis elegans as a model. The antioxidant activity was also evaluated, and antimycobacterial activity was assessed by the broth microdilution method. The compounds present in the aqueous extract mainly belonged to the flavonoid class (89%). The concentrations that showed protective effects in C. elegans against oxidative stress and antimycobacterial activity had no toxic effects. The antimycobacterial activity test demonstrated that the concentration of 1,560 µg mL−1 inhibited the growth and eradication of the mycobacterial tested strains. Based on our findings, the A. flaccida aqueous extract presents a viable potential in developing new phytotherapeutic drugs against mycobacteria of clinical relevance.
Frau von Brun
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1770
Subjects: Brun, Madalena vonidszbzzg

description: Mit aufgeklebtem Etikett, von Johann Caspar Lavater handschriftlich bezeichnet "Frau von Brun. Gutes, frommes Gesicht von feinen Sinnes für's Edle"
description: Aus der physiognomischen Studiensammlung von Johann Caspar Lavater |5 Exemplar der Zentralbibliothek Zürich, Graphische Sammlung und Fotoarchiv
title:  L’impresa azionaria tra struttura societaria e funzione sociale
Creators: name: Richter jr., Mario Stella
Publisher: name: Roma TrE-Press
Year: 2017

description: Se è solo nel corso del sec. XIX che emerge con evidenza la tensione tra struttura societaria e funzione sociale, il confronto tra questi due profili (individualistico il primo, incentrato sull’interesse sociale il secondo) finisce presto con l’identificare la sostanza stessa del diritto societario. Già vivace durante il fascismo, la riflessione dottrinaria sulla funzione sociale dell’impresa si fa intensa nel dopoguerra e prosegue anche nell’ultimo quarto del sec. XX. Nel nuovo secolo, però, la tradizionale lettura di questo rapporto che affidava alla legge nazionale la determinazione degli interessi ‘esterni’ che l’impresa azionaria doveva considerare, è stata messa in crisi dall’affermarsi dell’economia globale dove agiscono società sulle quali gli stati nazionali hanno scarse possibilità di intervento. A taluni pare che si debba affidare a quelle stesse società la tutela di interessi e beni di valenza sociale (teoria della responsabilità sociale d’impresa). Sull’efficacia di tale tutela - quando questa non comporti anche un vantaggio economico - è però lecito dubitare. Maggiore interesse sollevano invece le più recenti proposte che mirano a perseguire interessi pubblici attraverso l’intervento del privato.
description: La funzione sociale nel diritto privato tra XX e XXI secolo
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.12.1968, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.11.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)
Isolation of unique DNA sequences from uropathogenic Escherichia coli using a subtraction hybridization tecnique
Creators: name: Perkins, Mary Loring
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Etiology
subject: Genetics
subject: FOS: Biological sciences

description: Most Escherichia coli isolated from urinary tract infections appear to belong to highly defined clones and have a high incidence of virulence-associated factors.  Genes for hemolysin production (hly) and pyelonephritis-associated-pili (pap) have been isolated and their incidence found to correlate with severity of infection.  The highest incidence of these genes is found in pyelonephritis isolates, and a somewhat lower incidence is found in cystitis isolates.  However, a significant proportion of cystitis isolates are hly¯ and pap¯.  This finding has led to a question about the possible occurrence of other genetically determined cystitis virulence-associated factors.  If such genes exist, their isolation could help increase the understanding of E. coli pathogenicity as well as provide a useful clinical tool.  The goal of the studies reported here, was isolated unique sequences of DNA from a single cystitis isolate that encode for hly sequences and unique cystitis sequences.  To accomplish this a subtraction hybridization method was employed in which chromosomal DNA from a cystitis isolate (A16) was hybridized in a solution with excess biotinylated DNA from a non-pathogenic fecal isolate (J198).  After hybridization avidin was added and the solution was chromatographed over cupric-charged agarose.  This matrix selectively binds avidin and avidin-DNA complexes.  The effluent should contain only non-biotinylated DNA, enriched for unique A16 sequences which have no homology with J198 sequences.  The results of these define critical points in the subtraction hybridization method.  They demonstrate that biotinylated DNA in more hydrophobic than non-biotinylated DNA and that it has an increased tendency for non-specific absorption.  Several methods are evaluated to increase the recovery of biotin-DNA.  Additionally, these studies illustrated the importance of using a hybridization buffer that does not have substances (e.g., formamide and SDS) that interfere with cupric-chelate chromatography.  These studies also suggest that the subtraction hybridization method can be used to enrich chromosomal DNA.  Further work is required to isolate unique sequences of DNA from a cystitis isolate and to evaluate their incidence in virulent and non-virulent E. coli strains.
title:  Funzione sociale e processo civile fra XX e XXI secolo
Creators: name: Carratta, Antonio
Publisher: name: Roma TrE-Press
Year: 2017

description: Il lavoro prende in esame l’evoluzione della nozione di «funzione sociale» del processo civile, fra il XX e il XXI secolo a partire dalla riflessione di Franz Klein verso la fine del XIX secolo. Il lavoro si snoda attraverso tre diversi momenti storici o fasi nell’evoluzione di tale nozione. Una prima fase è quella delle origini, tradizionalmente collocata, appunto, sul finire del XIX secolo, nell’ambito della quale comincia a guardarsi al processo civile come ad un fenomeno o istituto che riguarda l’intera collettività e non solo le singole parti della lite. In questa prima accezione, l’idea della «funzione sociale» del processo civile trova ampia accoglienza anche presso giuristi di formazione liberale e costituisce la base ideologica anche per avanzare un nuovo metodo di studio del diritto processuale civile e per impostare nuove riforme della legislazione processuale esistente. Una seconda fase può essere individuata nella seconda metà del secolo XX, in coincidenza con l’introduzione delle nuove Costituzioni e l’affermazione del principio di uguaglianza sostanziale. In tale contesto per «funzione sociale» del processo civile si intende la concezione del processo come strumento di promozione sociale delle classi povere, con l’obiettivo di realizzare la c.d. uguaglianza sostanziale nei loro confronti. Una terza ed ultima fase è quella che si apre verso la fine del XX secolo ed è legata all’idea del processo civile come strumento di efficienza della società e della sua economia.
description: La funzione sociale nel diritto privato tra XX e XXI secolo
Towards Compromise User Experience Design in Ambient Intelligent Environment
Creators: name: Ander, Veronika
name: Cihelka, Petr
name: Tyrychtr, Jan
name: Novák, David
name: Ander, Veronika
name: Cihelka, Petr
name: Tyrychtr, Jan
name: Novák, David
Publisher: name: Unknown
Year: 2022
Subjects: subject: Research and Development/Tech Change/Emerging Technologies
subject: user experience
subject: interaction design
subject: user interface
subject: eye-tracking
subject: BeCoMe
subject: usability

description: Building, testing and evaluating UX for applications for Agricultural Ambient Intelligence Environments can be a difficult and time-consuming job. It can be an even longer and more challenging process due to their complexity and area of scope for complex intelligent systems. Many studies address the issue of UX design and evaluation of website user interface, mobiles, tangible equipment, wearable equipment and other, but it is necessary to look for UX deficiencies in all possible functions, every possible task. Depending on the structure of expert teams, experts’ opinions can vary broadly vary or may even contradict. This paper presents possibilities of use the Best-Compromise-Mean (BeCoMe) method for evaluation UX design. BeCoMe was not used for UX evaluation yet.
Pectinosoma elongata Arrow 1913
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Melolonthidae
Pectinosoma
Pectinosoma elongata

description: Pectinosoma elongata Arrow, 1913
Pectinosoma elongatum Arrow 1913b: 430 (Guyana - LECTOTYPE)
Distribution. Guyana: Arrow 1913b: 430; Blackwelder 1944: 234; Evans and Smith 2009: 260; Katovich 2011: 338; Fuhrmann and Vaz-de-Mello 2017: 42 (designation LECTOTYPE Pectinosoma elongatum). Venezuela (EO): Katovich 2011: 338 (EO).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 113, DOI: 10.5281/zenodo.3678492
Fotografische Sonnenaufnahme und zugehörige Zeichnung, unnummeriert.
Fotoabzug und durchgepauste Zeichnung der Aufnahme von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.09.1968, fotografiert von John S. Korintus
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Der Abzug ist auf der Rückseite mit genauen Angaben versehen. Flecken und Fackelflächen sind auf das Pauspapier übertragen. Im Jahresbericht für das vorliegende Jahr ist John S. Korintus nicht erwähnt
Von der mittelalterlichen Burg zur frühbarocken Vierflügelanlage – die ehemalige Kurfürstliche Burg in Boppard
Creators: name: Fischer, Doris
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 56 Nr. 3 (2015): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Computerized automated pulmonary disease diagnosis
Creators: name: Gerard, Martha Jane
Publisher: name: University of Utah
Year: 2012
Subjects: Lungs - Diseases - Diagnosis
Medicine - Data processing

description: This thesis details the design and implementation of a computerized system which generates a list of 5 differential diagnoses on patients with suspected pulmonary disease. A probabilistic diagnostic model, sequential applications of Bayes' Theorem, was used to calculate a series of likelihoods that a patient would have each of 29 different pulmonary diseases.  This approach to automated medical diagnosis was dependent on the facilities provided by the HELP system at LDS Hospital, a 550 bed tertiary care hospital located in Salt Lake City, Utah. After development and debugging of the medical logic, a retrospective study on 69 hospitalized patients with previously diagnosed pulmonary disease was conducted to measure the success of this system. The predictive logic was used to calculate the 5 most likely diseases for each patient. This differential diagnosis list contained the appropriate discharge diagnosis in 55 of 69 patients (80%). The medical logic (total 29 disease modules) yielded a sensitivity of 80% and specificity of 97%.  In a study of a subgroup of 18 patients having multiple pulmonary diseases the system correctly classified all pulmonary diseases present in 33% (6/18) of the cases. The overall sensitivity of this subgroup of patients with multiple pulmonary diseases was 64% and the specificity was 91%.  As judged from this preliminary study of the diagnostic logic, the method proved remarkably robust. These promising results have led to the installation of this system in a clinical setting.  It will be used in a prospective manner to study patients who have chest radiographs performed in the Radiology Department at LDS Hospital.
Inhalt
Creators: name: Redaktion, Die
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2022

description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 56 Nr. 3 (2015): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
Effect of antioxidant treatment on cardiac hypertrophy and antioxidant enzyme expression in cardiac specific glut4 deleted mice
Creators: name: Huang, Yujia
Publisher: name: University of Utah
Year: 2012
Subjects: Antioxidant
Cardiac hypertrophy
Glut4 deleted mice

description: We examined mice with cardiac specific deletion of the gene encoding glucose transporter 4 (GLUT4, G4H-/-). These mice develop moderate cardiac hypertrophy with normal basal cardiac function and show signs of mitochondrial and whole cell oxidative stress as evidenced by increased concentration of oxidized glutathione (GSSG). Preliminary research in our laboratory has shown that treatment with the antioxidant tempol (a whole cell antioxidant), but not MnTBAP (a mitochondrial targeted superoxide 2 mimetic), can attenuate cardiac hypertrophy. Furthermore, GSSG concentrations were not altered by tempol, but reduced by MnTBAP. Based on these preliminary data, we hypothesized that 1) glutathione peroxidase (Gpx) was elevated and glutathione reductase (Gsr) was lower in hearts of G4H-/- mice. Both Gpx and Gsr are important components of glutathione cycle. 2) MnTBAP treatment increases Gsr and lowers Gpx expression, but tempol did not affect either of them. 3) Tempol treatment can decrease GSK3? phosphorylation and increase Txn2 expression.  In contrast to our hypothesis, Gpx was not elevated in G4H-/- mice and Gsr levels were similar between G4H-/- and control. Treatment with either tempol or MnTBAP did  not affect Gpx protein levels. On the other hand, tempol reduced Gsr in G4H-/- mice vs. untreated G4H-/- and controls. GSK3? activity was similar between G4H-/- mice and controls and remained unchanged after tempol and MnTBAP. Txn2 expression was also similar between controls and G4H-/-. Tempol treatment increased Txn2 mRNA expression in controls only, but MnTBAP did not affect Txn2 in any group. Additionally, after tempol treatment, mRNA level of Gpx was not elevated in G4H-/- mice but actually lower, whereas Gsr was unchanged.  To sum up, the reduction of hypertrophy after tempol treatment was not associated with changes in; a) GSK3? phosphorylation, b) enzymes used in the glutathione oxidation and reduction cycle, or c) Txn2 expression. Additionally, though preliminary studies found a reduction of GSSG after MnTBAP treatment, the present study found this was not accompanied by any change in Gpx or Gsr. Therefore, we conclude that the attenuation of cardiac hypertrophy is unrelated to the modulation of oxidative stress by these enzymes, or a change in GSK3? phosphorylation.
title:  La famiglia tra funzione sociale e tutele individuali
Creators: name: Sesta, Michele
Publisher: name: Roma TrE-Press
Year: 2017

description: La famiglia da sempre ha svolto una funzione sociale, che già Cicerone aveva còlto quale fondamento della società civile e dello Stato. La Costituzione italiana dà ampio risalto alla società familiare, i cui diritti sono esplicitamente riconosciuti, con una formula che quasi configura un centro di interessi distinto da quello dei suoi componenti. L' a. sottolinea come, con riguardo alla famiglia, negli anni recenti l'ordinamento ha intrapreso un percorso inverso rispetto a quello degli istituti del diritto patrimoniale che, originariamente concepiti in un'ottica individualistica, sono stati ampiamente rivisitati in senso solidarista in considerazione della loro funzione sociale. Si è infatti progressivamente affermata la privatizzazione delle relazioni familiari, caratterizzata dalla tutela prioritaria delle ragioni dell'individuo rispetto quella dell'istituzione.
description: La funzione sociale nel diritto privato tra XX e XXI secolo
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.12.1968, erstellt am Sonnenobservatorium der Universität Teheran
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Zeichnung von Sonnenflecken (Bleistift und Farbstift), erstellt als Projektionsbildzeichnung in Teheran.
Unter Umständen im Zusammenhang mit Beobachtungen des Air Weather Service der U.S. Air Force im Auftrag des NASA Controll Centers in Houston erstellt. Instrument: unbekannt.
Instrument unbekannt
Cytotoxicity and anti-inflammatory activities of Gallesia integrifolia (Phytolaccaceae) fruit essential oil
Creators: name: de Campos Bortolucci, Wanessa
name: Raimundo, Keila Fernanda
name: Fernandez, Carla Maria Mariano
name: Calhelha, Ricardo C.
name: Ferreira, Isabel C. F. R.
name: Barros, Lillian
name: Gonçalves, José Eduardo
name: Linde, Giani Andrea
name: Colauto, Nelson Barros
name: Gazim, Zilda Cristiani
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: The chemical composition of Gallesia integrifolia fruits essential oil was obtained by hydrodistillation using a modified Clevenger apparatus was investigated by gas chromatography coupled to mass spectrometry (GC/MS). In addition, the cytotoxicity activity against human tumor cell lines MCF-7 (breast adenocarcinoma), NCI-H460 (large cell lung carcinoma), HeLa (cervical carcinoma), and HepG2 (hepatocellular carcinoma), and non-tumor PLP2 (porcine liver primary cells) as well as the anti-inflammatory action was proposal. The compounds were predominantly organosulfates (2,8-dithianonane, dimethyl trisulfide, and lenthionine). Anti-inflammatory activity that provides 50% inhibition of nitric oxide production (55 µg/mL) of essential oil of the fruits. It also presents cytotoxic activity against MCF-7 (GI50 = 66 µg/mL), NCI-H-460 (GI50 = 147 µg/mL), HeLa (GI50 = 182 µg/mL) and HepG2 (GI50 = 240 µg/mL). The essential oil is more active in tumor cells than in non-tumor cells and the GI50 values for essential oil reported in our work support future studies.