cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Le alterazioni dello splicing nei tessuti di pazienti con distrofia miotonica (DM): conseguenze fenotipiche e molecolari
Creators: name: RINALDI, FABRIZIO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: distofia miotonica; miRNAs; analisi di espressione; patogenesi; splicing
subject: distofia miotonica
subject: miRNAs
subject: analisi di espressione
subject: patogenesi
subject: splicing

description: 22. ciclo
Scambus strobilorum
Creators: name: Varga, Oleksandr
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Scambus
Scambus strobilorum

description: Scambus strobilorum (Ratzeburg, 1848)
Records. Ukraine (Kasparyan, 1981).
Material examined. lvano-Frankivsk Reg.: 1 ♀, Gorgany, m. Igrovets, SN, 7.5 km SW of Stara Guta, 48.598571 N, 24.130344 E, 1500 m, subalpine zone, SN, 1.vii.2012; 1 ♂, Gorgany, m. Syvulya, 12–13 km SW of Stara Guta, 48.531433 N, 24.132609 E, 1425 m, subalpine zone, SN, 14.vii.2012, leg. O. Varga.
Distribution. Palaearctic; Ukraine: lvano-Frankivsk Reg.
Biology. CMF. July.
description: Published as part of Varga, Oleksandr, 2019, Taxonomy and distribution of pimpline parasitoids (Hymenoptera, Ichneumonidae, Pimplinae) in Ukraine, pp. 1-65 in Zootaxa 4693 (1) on page 41, DOI: 10.11646/zootaxa.4693.1.1, http://zenodo.org/record/3529018
title: Responsabilità per fatto altrui: osservazione dal sistema della responsabilità extracontrattuale
title: Liability for others: observation from the system of non-contractual liability
titleType: AlternativeTitle
Creators: name: DOU, HAIYANG
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: responsabilità per fatto altrui; diritto italiano; sistema romanistico della responsabilità extracontrattuale; actio noxalis adversus paterfamilias; actiones furti et damni in factum adversus nautas caupones stabularios; responsabilità dei sorveglianti per il fatto degli incapaci; responsabilità dei genitori e dei sostituti per il fatto dei minori; responsabilità dei preponenti per il fatto dei preposti; diritto cinese; diritto romano
subject: responsabilità per fatto altrui
subject: diritto italiano
subject: sistema romanistico della responsabilità extracontrattuale
subject: actio noxalis adversus paterfamilias
subject: actiones furti et damni in factum adversus nautas caupones stabularios
subject: responsabilità dei sorveglianti per il fatto degli incapaci
subject: responsabilità dei genitori e dei sostituti per il fatto dei minori
subject: responsabilità dei preponenti per il fatto dei preposti
subject: diritto cinese
subject: diritto romano

description: 22. ciclo
Tetrix guinanensis Zheng & Jiang 2002
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix guinanensis

description: 69. Tetrix guinanensis Zheng & Jiang, 2002
Specimens examined. 13 ♂ 4♀, Fangcheng (Dongzhong), 21°38’N, 107°38’E, 400m alt, 24 Jul. 2013, collected by Yi-Feng Wei.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on pages 172-173, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 1: of Unfavourable risk factor control after coronary events in routine clinical practice
Creators: name: Sverre, Elise
name: Peersen, Kari
name: Husebye, Einar
name: Gjertsen, Erik
name: Gullestad, Lars
name: TorbjĂ¸Rn Moum
name: Otterstad, Jan
name: Dammen, Toril
name: Munkhaugen, John
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology
subject: Computational Biology

description: Multi-adjusted odds ratio for unfavourable coronary risk factors 2-36 months after the index coronary event. (DOCX 16 kb)
RAQAMLI IQTISODIYOTNING AFZALLIKLARI
Creators: name: Qodirov, Farrux
name: Ochilova, Gulsanam
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada raqamli iqtisodiyotning afzalliklari, uning zamonaviy iqtisodiy tizimga ta'siri va rivojlanishining ahamiyati ko‘rib chiqiladi. Maqola raqamli texnologiyalarning iqtisodiy jarayonlarga qanday integratsiya qilinishi, yangi imkoniyatlarni yaratishi va an'anaviy iqtisodiyotga nisbatan qanday ustunliklarni taqdim etishi haqida chuqur tahlil beradi. Raqamli iqtisodiyotning samaradorligi, ishbilarmonlik jarayonlaridagi tezlik, narxlarni pasaytirish va yangi ish o‘rinlarini yaratish kabi jihatlar xususida muhokama qilinadi. Maqolada shuningdek, raqamli iqtisodiyotning dunyo bo‘ylab keng tarqalishi, uning iqtisodiy o‘sish va rivojlanishga qo‘shgan hissasi, shuningdek, kamchiliklari va xavflari ham yoritiladi.
Foslevodopa/foscarbidopa (LDp/CDp) in advanced Parkinson’s Disease (aPD): demonstration of savings from a societal perspective in the UK
Creators: name: Chaudhuri, K Ray
name: Bergmann, Lars
name: Belsey, Jonathan
name: Boodhna, Trishal
name: Leoncini, Emanuele
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: In advanced Parkinson’s disease (aPD), adequate 24-hour control of OFF-time may not be achievable using oral/transdermal therapies. Clinical trials of foslevodopa/foscarbidopa (LDp/CDP) demonstrate meaningful reductions in OFF-time and OFF-related sleep disturbance in aPD. Previous analyses have only considered direct medical costs: this analysis considers a broader societal perspective (direct non-medical costs, informal care, loss of earnings, productivity and tax). Inputs for the societal impact model were taken from a cost-utility model comparing LDp/CDp with best medical treatment (BMT), accepted by the UK National Institute of Health and Care Excellence (NICE). Quintiles of normalized OFF-time across a 16-hour waking day in each treatment group were applied to literature-based estimates for direct medical, non-medical and indirect costs. The resulting state-specific cost estimates were applied to the modelled aPD patient population. The model estimates the potential UK population for LDp/CDp at 17,505. Continuous 24-hour delivery of LDp/CDp results in greater time spent in in OFF-time states 0-1 (0-4 hours of OFF-time/16-hour waking day) vs BMT alone. Net savings if all eligible patients receive LDp/CDp are £79.1M in year 1, £235.4M in year 2, rising to £262.2M in year 3, declining to £222.9M in year 4 and £153.7M in year 5 as disease progresses and efficacy of LDp/CDp declines, Estimated total net savings are £953M after 5 years. Results are robust in scenario analyses (excluding costs of excessive sleepiness, earnings loss, productivity and tax loss). A NICE-accepted model was used as the economic modelling basis for the societal impact model, however, much of the data was derived from Adelphi datasets, with the potential for inconsistent definitions. When considered from a societal perspective, the use of LDp/CDp in aPD patients inadequately controlled on oral therapy, is associated with net healthcare and societal annual savings of over £79.1M vs BMT.
Reconstructing the Earth in Deep-Time: A New and Open Framework for the PANALESIS Model
Creators: name: Franziskakis, Florian
Publisher: name: Zenodo
Year: 2024
Subjects: PANALESIS
Plate Tectonics
Open Data
FAIR
Modelling
Tectonics
QGIS
Plugin
Open Science
Open-source

description: Presentation given at the European Geosciences Union (EGU) 2024 General Assembly for Session ITS1.8/TS9.1 "Navigating the Digital Earth: Advancements in Earth Systems and Geophysical Inference".

 

Abstract:

The Panalesis model (Vérard, 2019) was developed in a preliminary version according to concepts, methods and tools that follow the work carried out for more than 20 years at the University of Lausanne (Stampfli & Borel, 2002; Hochard, 2008). Although the techniques are relevant, development under ArcGIS® does not allow visibility and easy accessibility of the model to the scientific community.

A major effort is therefore underway to migrate the entire model to an open source version using a FAIR approach for research software (Chue Hong et al., 2021). This migration concerns both the plate tectonic maps covering all the world over the entire Phanerozoic and part of the Neoproterozoic, but also the creation of paleoDEMs (global quantified topographies).

The Panalesis model and its entire architecture is therefore currently migrated to QGIS (a free and open source geographic information system). TopographyMaker, the software designed to convert polylines from the reconstruction map into a points grid with elevation values is now working as a plugin on QGIS. The output palaeoDEMS will also be published according to the FAIR principles for scientific data management and stewardship (Wilkinson et al., 2016).

The development and future refinements of TopographyMaker will enhance the Earth system modelling, especially coupling between models of different shells of the Earth such as atmospheric circulation, climatic evolution, and mantle dynamics. The topography is, for instance, considered a first order controlling factor for CO2 evolution over geological timescales, through silicate weathering (MacDonald et al., 2019).
Narrative review of value frameworks in urothelial carcinoma and positioning of enfortumab vedotin
Creators: name: Nunez, Aurora Ortiz
name: Portela, Judit Gonzalez
name: Zozaya, Néboa
name: Fernández, Irene
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Evaluate existing oncology value frameworks in terms of their methodology, structure, characteristics, and functionality using the example of enfortumab vedotin, an approved therapy for urothelial carcinoma. A search of PubMed, grey literature, and official websites of relevant international organizations was performed from January 2022 to March 2023. Six frameworks were identified and analyzed, including the American Society of Clinical Oncology’s assessment framework, European Society for Medical Oncology’s Magnitude of Clinical Benefit Scale, the National Comprehensive Cancer Network’s Evidence Blocks, Memorial Sloan Kettering Cancer Center’s DrugAbacus, Institute for Clinical and Economic Review’s assessment framework, and the Drug Assessment Framework. Comparisons across frameworks were challenging, owing to differing approaches, objectives, perspectives, methodology, and criteria. Based on the results of the EV-301 study (NCT03474107), the European Society for Medical Oncology’s Magnitude of Clinical Benefit Scale assigned a score of 4 out of 5 to enfortumab vedotin administered after chemotherapy and immunotherapy. The National Comprehensive Cancer Network’s Evidence Blocks enabled assessment of enfortumab vedotin compared with other treatments for locally advanced or metastatic urothelial carcinoma, resulting in the positioning of enfortumab vedotin as a preferred regimen after chemotherapy and immunotherapy. Application of value frameworks in oncology can contribute to informed value-based decision-making. However, comparisons across frameworks should be made with caution and limited to the same lines of treatment. Enfortumab vedotin may contribute to optimizing outcomes in patients previously treated with chemotherapy and immunotherapy for locally advanced or metastatic urothelial carcinoma.
Additional file 1: of Unfavourable risk factor control after coronary events in routine clinical practice
Creators: name: Sverre, Elise
name: Peersen, Kari
name: Husebye, Einar
name: Gjertsen, Erik
name: Gullestad, Lars
name: TorbjĂ¸Rn Moum
name: Otterstad, Jan
name: Dammen, Toril
name: Munkhaugen, John
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: Mental Health
subject: Hematology
subject: Computational Biology

description: Multi-adjusted odds ratio for unfavourable coronary risk factors 2-36 months after the index coronary event. (DOCX 16 kb)
Cost-effectiveness of TOMAC therapy for medication-refractory restless legs syndrome: an updated analysis based on extension study data
Creators: name: Ryschon, Anne M.
name: Roy, Asim
name: Pietzsch, Jan B.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Pharmacology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Aims Patients with medication-refractory restless legs syndrome (RLS) have limited therapeutic options available for symptom relief. Tonic motor activation (TOMAC) presents a novel, non-invasive therapy for this patient population. The aim of this study was to conduct an updated cost-effectiveness analysis of TOMAC therapy based on recently available longer-term follow-up data. Materials and Methods A previously published decision-analytic Markov model was utilized to project strategy-specific costs and outcomes over three-years and lifetime for TOMAC compared to status quo treatment (control). Cohort characteristics were based on 24-week clinical data from the extension cohort of the RESTFUL study, which included longer-term follow-up of RESTFUL completers who were assigned to continue or discontinue TOMAC use (TOMAC and control, respectively). The primary analysis outcome was the incremental cost-effectiveness ratio (ICER) in $per quality-adjusted life year (QALY) gained, calculated using change in International RLS Study Group Rating Scale (IRLS) score as the effect measure. Extensive sensitivity analyses were performed. Results TOMAC treatment improved IRLS by 5.9 versus control, resulting in estimated utility improvement of +0.05. Over three-years and lifetime, TOMAC added 0.14 and 0.73 QALYs, at incremental costs of $6,751 and $27,440, resulting in projected ICERs of $47,609 and $37,823 per QALY gained, respectively. TOMAC was found to be cost-effective across all tested sensitivity analyses. Limitations and Conclusion The inclusion of longer follow-up data in the current analysis confirms earlier exploratory cost-effectiveness findings and suggest TOMAC therapy may provide a high-value treatment option for patients with medication-refractory RLS. Restless Legs Syndrome (RLS) is a is a neurological disorder, usually chronic, that causes an overwhelming urge to move one’s legs, with pronounced implications for patients’ quality of life. While pharmaceutical treatment options exist, a substantial proportion of patients are considered refractory to drug treatment. Tonic motor activation (TOMAC) therapy is a novel non-invasive neurostimulation approach that was recently cleared for market in the United States. This study sought to provide an updated economic analysis based on recently available data with longer follow-up. The findings of this study, based on data from the RESTFUL extension study, suggest TOMAC therapy can be a high-value treatment alternative for refractory patients, providing meaningful quality of life improvement at costs that render it cost-effective in the United States. Future data with further extended follow-up will be useful to further broaden the evidence base underpinning these findings.
Tetrix tenuicornis Sahlberg 1891
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix tenuicornis

description: 70. Tetrix tenuicornis (Sahlberg, 1891)
Specimens examined. 6 ♂ 8♀, Fangcheng (Dongzhong), 21°38’N, 107°38’E, 350m alt, 24 Jul. 2013, collected by Yi-Feng Wei.
Distribution. Whole China; all Europe; Russia; Asian part of Turkey; Kazakhstan; Mongolia; Japan.
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 173, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
La fondazione della FDJ
Creators: name: MIGLIOZZI, SERENA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: Freie Deutsche Jugend; Unione Sovietica; Germany; questione tedesca; SED; KPD; gioventù; zona di occupazione sovietica
subject: Freie Deutsche Jugend
subject: Unione Sovietica
subject: Germany
subject: questione tedesca
subject: SED
subject: KPD
subject: gioventù
subject: zona di occupazione sovietica

description: 22. ciclo
Inflation-adjusted analysis of ICER’s Unsupported Price Increase reports: contextualizing drug spending changes
Creators: name: Wagner, Tyer D.
name: Westrich, Kimberly D.
name: Nordyke, Robert J.
name: Campbell, Jon D.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health

description: The Institute for Clinical and Economic Review (ICER) publishes annual Unsupported Price Increase (UPI) reports on prescription drugs, which have gained attention from policymakers and healthcare stakeholders. These reports do not adjust for inflation in their analyses of net price changes. This study aimed to evaluate the economic context of reported drug price increases in ICER’s UPI reports by applying inflation adjustments to the estimated impact on healthcare spending. Separate inflation adjustments using the Medical Consumer Price Index (Medical CPI) and the Consumer Price Index for All Urban Consumers (CPI-U) were applied to unadjusted UPI findings. The study analyzed data from four most recent UPI reports spanning pricing data from 2018 to 2019 (report year 2020) to 2021 to 2022 (report year 2023), focusing on drugs classified as having “unsupported” price increases. Inflation-adjusted analyses showed lower estimates of real changes in spending compared to ICER’s unadjusted figures across all drugs analyzed. Across the four UPI reports, the average report-year difference in Medical CPI inflation adjustment spending versus unadjusted findings was 53%, whereas the average report-year difference in CPI-U inflation adjustment spending versus unadjusted findings was 80%. In the most recent report year of 2023, ICER’s unadjusted estimate of a $1.3 billion increase in healthcare spending transformed to a $134 million decrease when adjusted by Medical CPI and a $1.51 billion decrease when adjusted by CPI-U. This study demonstrates that inflation adjustment can alter not only the findings but also the interpretation of drug spending changes in UPI reports. The findings highlight the importance of considering economic context in evaluating drug pricing trends and suggest that unadjusted figures may overstate the impact of real price changes. Given the influence of these reports on policy discussions, incorporating inflation adjustments into analyses is one of many steps toward informing evidence-based policy decisions.
Additional file 1: Figure S1a. of Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells
Creators: name: Rao, Shalini
name: Solum, Guri
name: Niederdorfer, Barbara
name: Nørsett, Kristin
name: Bjørkøy, Geir
name: Thommesen, Liv
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Expression of CCKBR in gastric adenocarcinoma cells. AGS cells have low abundance of the CCKBR, MKN45 express the CCKBR endogenously and AGS-Gr cells are stably transfected with the CCKBR. S1b. Negative control images of the MKN45 cells stained for the CCKBR (phase contrast, Alexa 488, Draq5). Figure S2: Gastrin induces autophagy. AGS-Gr (a & b) cells treated with gastrin (10 nM), BafA1 (100 nM) and gastrin + BafA1 for 2 and 4 h. Protein expression of MAP1LC3B-II and SQSTM1 was analyzed by immunoblotting. The images shown represent one of three independent experiments. Graphs show mean +/- SEM (P- values: *** ≤ 0.01 **≤ 0.02, and * ≤ 0.05). Figure S3: Negative controls (primary antibodies omitted) for MAP1LC3B (Alexa 488) and SQSTM1 (Alexa 647). Figure S4: Gastrin mediated survival is dependent on autophagy. (a): A representative cytometric plots showing AGS-Gr cells treated with BafA1 and gastrin for 18 h. Cell viability was assessed using annexin V-PI staining and flow cytometric analyses. Blocking autophagy reduces gastrin mediated survival in AGS-Gr cells. (b): Cell viability assessed in AGS-Gr cells treated with gastrin (10 nM) for 6- 72 h. (c & d): Cells treated with gastrin (2 h) and subsequently treated with increasing concentrations of cisplatin. Viability was assessed at 24 and 72 h. Results show mean +/-SD (n=3, P-values: * ≤ 0.05 ** ≤ 0.01 *** ≤ 0.001). (e): AGS-Gr cells treated with HCQ for 8 h. Protein expression of MAP1LC3B-II and SQSTM1 was detected by immunoblotting. (f) Gastrin induced autophagy is dependent on ULK1: AGS-Gr cells treated with gastrin, BafA1 and ULK1 inhibitor SBI-0206965 (10 μM) for 4 h. Protein expression of MAP1LC3B-II and SQSTM1 was detected by immunoblotting. The immunoblots represent one of three independent experiments. Figure S5: Inhibition of gastrin induced autophagy by Comp C. AGS-Gr cells pretreated with Compound C (10 μM) for 12 h before adding BafA1 and gastrin (4 h). Protein expression of SQSTM1 is shown by immunoblotting. The blot represents one of two independent experiments. (DOCX 2504 kb)
title: Gli aspetti fiscali delle procedure concorsuali
title: Fiscal aspects of the bankruptcy claims process
titleType: AlternativeTitle
Creators: name: FAZZINI, ELISA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: insolvenza; crisi; aspetti fiscali; transazione fiscale; credito tributario
subject: insolvenza
subject: crisi
subject: aspetti fiscali
subject: transazione fiscale
subject: credito tributario

description: 22. ciclo
Tetrix nigromaculata Zheng & Shi 2002
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix nigromaculata

description: 71. Tetrix nigromaculata Zheng & Shi, 2002
Specimens examined. 7 ♂ 6♀, Fangcheng (Dongzhong) 21°38’N, 107°38’E, 500m alt, 17 Jul. 2013, collected by Yi-Feng Wei.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 173, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Economic and healthcare resource utilization assessments of pet imaging in coronary artery disease diagnosis: a systematic review and discussion of opportunities for future economic evaluations
Creators: name: Ferko, Nicole
name: Priest, Stacey
name: Almuallem, Lamees
name: Mooradally, Alicyia Walczyk
name: Wang, Di
name: Ramirez, Abril Oliva
name: Szabo, Erika
name: Cabra, Arturo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Cell Biology
Environmental Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Aims: This systematic literature review (SLR) consolidated economic and healthcare resource utilization (HCRU) evidence for positron emission tomography (PET) and single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) to inform future economic evaluations. Materials and Methods: An electronic search was conducted in MEDLINE, Embase, and Cochrane databases from 2012-2022. Economic and HCRU studies in adults who underwent PET- or SPECT-MPI for coronary artery disease (CAD) diagnosis were eligible. A qualitative methodological assessment of existing economic evaluations, HCRU, and downstream cardiac outcomes was completed. Exploratory meta-analyses of clinical outcomes were performed. Results: The search yielded 13,439 results, with 71 records included. Economic evaluations and comparative clinical trials were limited in number and outcome types (HCRU, downstream cardiac outcomes, and diagnostic performance) assessed. No studies included all outcome types and only one economic evaluation linked diagnostic performance to HCRU. The meta-analyses of comparative studies demonstrated significantly higher rates of early- and late-invasive coronary angiography and revascularization for PET- compared to SPECT-MPI; however, the rate of repeat testing was lower with PET-MPI. The rate of acute myocardial infarction was lower, albeit non-significant with PET- vs. SPECT-MPI. Limitations and Conclusions: This SLR identified economic and HCRU evaluations following PET- and SPECT-MPI for CAD diagnosis and determined that existing studies do not capture all pertinent outcome parameters or link diagnostic performance to downstream HCRU and cardiac outcomes, thus, resulting in simplified assessments of CAD burden. A limitation of this work relates to heterogeneity in study designs, patient populations, and follow-up times of existing studies. Resultingly, it was challenging to pool data in meta-analyses. Overall, this work provides a foundation for the development of comprehensive economic models for PET- and SPECT-MPI in CAD diagnosis, which should link diagnostic outcomes to HCRU and downstream cardiac events to capture the full CAD scope.
title: La salute organizzativa degli infermieri
title: Nursing organizational health
titleType: AlternativeTitle
Creators: name: SILI, ALESSANDRO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: infermieri; salute organizzativa; infermieri dirigenti; strumenti di ricerca; organizzazione
subject: infermieri
subject: salute organizzativa
subject: infermieri dirigenti
subject: strumenti di ricerca
subject: organizzazione

description: 22. ciclo
description: CAPITOLO 1 La Salute Organizzativa 1.1. Il moderno concetto della Dirigenza Infermieristica 1.2. Organizzazione e persone: il coordinamento dei professionisti sanitari 1.3. Il Benessere Organizzativo nelle organizzazioni sanitarie 1.4. Dal “benessere” alla “salute” organizzativa. - CAPITOLO 2 Lo sviluppo del programma di ricerca 2.1. Revisione della letteratura 2.2. Il progetto di ricerca. - CAPITOLO 3 Validità e affidabilità del Questionario Infermieristico sulla Salute Organizzativa [Professioni Infermieristiche 2010; 63(1), 27-37] 3.1. Introduzione 3.2. Materiali e metodi 3.3. Risultati 3.4. Discussione 3.5. Conclusioni 3.6. Bibliografia. - CAPITOLO 4 Organizational health and quality of life: survey among nurses on territorial emergency [Journal of Advanced Nursing (in press)] 4.1. Introduction 4.2. Background 4.3. The Study 4.4. Results 4.5. Discussion 4.6. Conclusion 4.7. References. - CAPITOLO 5 Infermieri di Camera Operatoria e Infermieri di Medicina Generale: la diversa percezione della propria Salute Organizzativa [La Medicina del Lavoro (in press)] 5.1. Introduzione 5.2. Metodo 5.3. Risultati 5.4. Discussione 5.5. Bibliografia. - CAPITOLO 6 La Salute Organizzativa degli Infermieri: guida pratica all’utilizzo del Questionario Infermieristico sulla Salute Organizzativa [EdiSES, Roma 2010] 6.1. Articolazione del Manuale 6.2. Il Manuale 6.3. Sommario 6.4. Premessa 6.5. Presentazione. - Conclusioni
Additional file 2: of Plantamajoside from Plantago asiatica modulates human umbilical vein endothelial cell dysfunction by glyceraldehyde-induced AGEs via MAPK/NF-κB
Creators: name: Won-Rak Son
name: Nam, Mi-Hyun
name: Chung-Oui Hong
name: Yoonsook Kim
name: Kwang-Won Lee
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Figure S2. Cytotoxicity of N-acetylcysteine (NAC). The NAC cytotoxicity in the HUVECs was determined by MTT assay. Cells were treated with various concentrations of NAC for 24 h. Results were analyzed with Duncan’s multiple range test as means ± SD for triplicate experiments. Significant differences were indicated by p
Additional file 2: of Impact of trauma system structure on injury outcomes: a systematic review protocol
Creators: name: Moore, Lynne
name: Champion, Howard
name: OâReilly, Gerard
name: Leppaniemi, Ari
name: Cameron, Peter
name: Palmer, Cameron
name: Abu-Zidan, Fikri
name: Gabbe, Belinda
name: Gaarder, Christine
name: Yanchar, Natalie
name: Stelfox, Henry
name: Coimbra, Raul
name: Kortbeek, John
name: Noonan, Vanessa
name: Gunning, Amy
name: Leenan, Luke
name: Gordon, Malcolm
name: Khajanchi, Monty
name: MichĂ¨Le Shemilt
name: ValĂŠrie Porgo
name: Turgeon, Alexis
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Search strategy for MEDLINE and EMBASE. Tables describing preliminary search strategy and results for MEDLINE and EMBASE searches. (PDF 102Â kb)
Results from risk, co-benefit and trade-off assessment
Creators: name: Ismangil, David
name: Lieu, Jenny
Publisher: name: Zenodo
Year: 2023

description: This deliverable assesses the risks, opportunities and trade-offs of individual LMTs. Stakeholders were interviewed across the LANDMARC consortium these aspects. We then synthesized stakeholder’s perspective of risks of each LMTs and compared. The key findings are that stakeholders’ perspective highlight contextual issues that impact individuals’ livelihoods as well as longer terms issues in policy consistency. We then reflected to which extent these risks could be considered in models and provide some first insights on scaling up from individual LMTs to LMT portfolios.
Tetrix grossifemura Zheng & Jiang 1997
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix grossifemura

description: 72. Tetrix grossifemura Zheng & Jiang, 1997
Specimens examined. 4 ♂ 8♀, Fangcheng (Dongzhong), 21°41’N, 107°36’E, 400m alt, 18 Jul. 2013, collected by Yi-Feng Wei.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 173, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
title: Analisi computazionale dell’aeroacustica di un pneumatico in rotolamento
title: Computational aeroacoustic analysis of a rolling tire
titleType: AlternativeTitle
Creators: name: FABRIZI, CARLO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: CFD; LES; CAA; aerodinamics; acoustics; noise; tire; pipe; resonance; RANS
subject: CFD
subject: LES
subject: CAA
subject: aerodinamics
subject: acoustics
subject: noise
subject: tire
subject: pipe
subject: resonance
subject: RANS

description: 21. ciclo
A real-world assessment of healthcare costs associated with agitation in Alzheimer’s dementia
Creators: name: Grossberg, George
name: Urganus, Annette
name: Schein, Jeff
name: Bungay, Rebecca
name: Cloutier, Martin
name: Gauthier-Loiselle, Marjolaine
name: Chan, Deborah
name: Guerin, Annie
name: Aggarwal, Jyoti
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: To describe and compare clinical characteristics, healthcare costs, and institutionalization/mortality outcomes among patients with and without agitation associated with Alzheimer’s dementia (AAD). Data from the Reliant Medical Group database (01/01/2016-03/31/2020) were used, including claims, electronic medical records, and clinical information/physician notes abstracted from medical charts. Patients aged ≥55 years with Alzheimer’s dementia (AD) were observed during a randomly selected 12-month study period after AD diagnosis. Using information recorded in medical charts, patients were classified into cohorts based on experiencing (agitation cohort) and not experiencing (no agitation cohort) agitated behaviours during the study period. Entropy balancing was used to create reweighted cohorts with similar characteristics. Study outcomes (patient demographic and clinical characteristics, treatments received, healthcare costs, institutionalization and death events) were compared between cohorts; agitation characteristics were described for the agitation cohort only. Among 711 patients included in the study, 240 were classified in the agitation cohort and 471 in the no agitation cohort. After reweighting, several comorbidities were more frequently observed in the agitation versus no agitation cohort, including infection, depression, and altered mental status. Use of antidepressants, anticonvulsants, antipsychotics, and antianxiety medications was more common in the agitation versus no agitation cohort. Common agitated behaviours included hitting (20.8%), pacing/aimless wandering (17.5%), and cursing/verbal aggression (15.0%). Total all-cause healthcare costs were $4287 per-patient-per-year higher in the agitation cohort versus no agitation cohort (p = 0.04), driven by higher inpatient costs. Death was more common and time to death and institutionalization were shorter in the agitation versus no agitation cohort. Results may not be generalizable to the US population with AD. Among patients with AD, agitation was associated with shorter time to death/institutionalization and increased comorbidities, medication use, and healthcare costs, highlighting the additional clinical and economic burden that agitation poses to patients and the healthcare system.
Applicazioni della tecnologia RFId in ambito sanitario
Creators: name: ARMISI, LUCA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: RFId; ingegneria medica; sacche ematiche; manutenzione; garze laparotomiche
subject: RFId
subject: ingegneria medica
subject: sacche ematiche
subject: manutenzione
subject: garze laparotomiche

description: 20. ciclo
description: 1 Riassunto 2 Introduzione 3 La tecnologia RFId 3.1 Descrizione di un sistema RFId 3.2 Transponder 3.2.1 Classificazone dei tag 3.2.2 Parametri per la scelta di un tag 3.3 Reader 3.3.1 Classificazione reader 3.4 Frequenze di comunicazione tag-reader 3.5 Sistemi di comunicazione RFId 3.5.1 Il processo di modulazione della portante 3.5.2 La codifica dei dati 3.5.3 Rilevamento e correzione degli errori 3.6 Standard di comunicazione 3.6.1 Lo standard ISO 3.6.2 Lo standard EPCglobal 3.7 Allocazione in frequenza 3.7.1 Situazione mondiale 3.7.2 Situazione europea 3.7.3 Situazione nazionale 3.8 Normative in ambito ospedaliero sulla compatibilità elettromagnetica 4 Principi fisici dei sistemi RFId 4.1 Principi di campi elettromagnetici 4.1.1 Onda elettromagnetica 4.1.2 Le equazioni di Maxwell 4.2 Accoppiamento tag/reader 4.2.1 L’accoppiamento induttivo 4.2.2 L’accoppiamento elettromagnetico 4.3 Antenne nei sistemi RFId 4.3.1 Elementi base di teoria delle antenne 4.3.2 Antenne per tag 4.3.3 Antenne per reader 4.4 Read range di un sistema RFId 5 Le applicazioni 5.1 Le applicazioni in ambito industriale 5.1.1 Trasporto pubblico locale 5.1.2 Pubblica amministrazione 5.1.3 Educazione ed intrattenimento 5.1.4 Trasporto merci 5.1.5 Gestione dei pagamenti 5.1.6 Largo consumo 5.1.7 Lusso e moda 5.1.8 Settore alimentare 5.1.9 Logistica interna 5.2 Le applicazioni in ambito sanitario 5.2.1 Identificazione mamma-neonato 5.2.2 Logistica e gestione del farmaco 5.2.3 Localizzazione paziente all’interno dell’area del Pronto Soccorso 5.2.4 Un tag come misuratore di glicemia 5.3 Analisi costi e benefici 6 Progetti svolti presso il Servizio di Ingegneria Medica del Policlinico Tor Vergata 6.1.1 Sistema di supporto alla gestione della filiera trasfusionale 6.1.2 Finalità del progetto di ricerca 6.1.3 Requisiti del sistema 6.1.4 Scelta del sistema RFId utilizzato per la sperimentazione 6.1.5 Conclusioni del progetto 6.2 Progettazione di un sistema per conteggio ed identificazione di garze laparotomiche 6.2.1 Finalità del progetto di ricerca 6.2.2 Requisiti del sistema 6.2.3 Scelta del sistema RFId utilizzato per la sperimentazione 6.2.4 Prove sperimentali 6.2.5 Definizione delle caratteristiche ottimali del sistema RFId 6.2.6 Conclusioni del progetto 6.3 Supporto alla gestione della manutenzione 6.3.1 La gestione della manutenzione presso il Policlinico Tor Vergata 6.3.1 Finalità del progetto di ricerca 6.3.2 Requisiti del sistema 6.3.3 Componenti del sistema RFId utilizzato 6.3.4 Misure effettuate 6.3.5 Realizzazione del software di gestione del sistema 6.3.6 Elaborazione del software di scrittura 6.3.7 Elaborazione del software di lettura 6.3.8 Conclusioni del progetto 7 Conclusioni
Tetrix dentifemura Zheng & Shi 2003
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix dentifemura

description: 73. Tetrix dentifemura Zheng & Shi, 2003
Specimens examined. 16 ♂ 6♀, Fangcheng (Dongzhong), 21°44’N, 107°38’E, 450m alt, 17 Jul. 2013, collected by Yi-Feng Wei.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 173, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Cost-effectiveness and impact on infections and associated antimicrobial resistance of 20-valent pneumococcal conjugate vaccine in US children previously immunized with PCV13
Creators: name: Rozenbaum, Mark H.
name: Huang, Liping
name: Cane, Alejandro
name: Arguedas, Adriano
name: Chapman, Ruth
name: Dillon-Murphy, Desmond
name: Tort, Maria J.
name: Snow, Vincenza
name: Chilson, Erica
name: Farkouh, Raymond
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: The US Food and Drug Administration approved the 20-valent pneumococcal conjugate vaccine (PCV20) to prevent pneumococcal disease. In the context of routine PCV20 vaccination, we evaluated the cost-effectiveness and public health and economic impact of a PCV20 catch-up program and estimated the number of antibiotic prescriptions and antibiotic-resistant infections averted. A population-based, multi-cohort, decision-analytic Markov model was developed using parameters consistent with previous PCV20 cost-effectiveness analyses. In the intervention arm, children aged 14–59 months who previously completed PCV13 vaccination received a supplemental dose of PCV20. In the comparator arm, no catch-up PCV20 dose was given. The direct and indirect benefits of vaccination were captured over a 10-year time horizon. A PCV20 catch-up program would prevent 5,469 invasive pneumococcal disease cases, 50,286 hospitalized pneumonia cases, 218,240 outpatient pneumonia cases, 582,302 otitis media cases, and 1,800 deaths, representing a net gain of 30,014 life years and 55,583 quality-adjusted life years. Furthermore, 720,938 antibiotic prescriptions and 256,889 antibiotic-resistant infections would be averted. A catch-up program would result in cost savings of $800 million. These results were robust to sensitivity and scenario analyses. A PCV20 catch-up program could prevent pneumococcal infections, antibiotic prescriptions, and antimicrobial-resistant infections and would be cost-saving in the US.
title: Bewegung beobachten und bewerten: Nutzen und Grenzen einer Diagnostik des Werfens
titleType: Other
Creators: name: Wilhelm, Andreas
name: Büsch, Dirk
Publisher: name: Deutsche Sporthochschule Köln
Year: 2024

description: Die Beurteilung einer Bewegungsfertigkeit im Sportunterricht bzw. einer Technik im Sport erfordert Beobachtungskriterien und eine geeignete Diagnostik relevanter Bewegungsmerkmale. Während quantitative Analyseverfahren mit einem hohen
technisch-apparativen Aufwand verbunden sind, können objektive und zuverlässige Aussagen auch mit praktikablen qualitativen Analyseverfahren getroffen werden, wenn Lehrer:innen und/oder Trainer:innen zu identischen Bewertungen
kommen. Eine wesentliche Voraussetzung dafür sind Beobachtungsinstrumente, die auf einer theoretisch-inhaltlichen Begründung der Beobachtungsmerkmale und einer sachlichen, nicht beeinflussenden (standardisierten) Instruktion beru-
hen. Am Beispiel einer Wurfbewegung wird ein Beobachtungsbogen zu 15 Bewegungsmerkmalen des Schlagwurfs im Handball vorgestellt, der sich an den Funktionsphasen des Wurfs orientiert. Der Beobachtungsbogen wurde hinsichtlich der Beurteiler:innenübereinstimmung (Inter-Rater-Objektivät) geprüft. Im Rahmen einer Untersuchung bewerteten 121 Sportstudierende mit Hilfe des Beobachtungsbogens zwei Schlagwürfe in unterschiedlicher Ausführungsqualität, die den
Sportstudierenden zum Selbststudium als Video zur Verfügung gestellt wurden. Die Ergebnisse zeigen für den größten Teil der 15 Bewegungsmerkmale hohe Beurteiler:innenübereinstimmungen. Als Ursache geringer Überstimmungen kann
eine Wechselwirkung der Güte des Beobachtungsbogens, des Präsentationsmodus und Beobachtungskompetenz angenommen werden, die in weiteren systematischen Studien zu prüfen sind, da kriterienorientierte Beobachtungsinstrumente eine wesentliche Voraussetzung für zuverlässige und valide Beurteilungen in Schul- und
Trainingskontexten darstellen.
MOESM1 of A randomised, active- and placebo-controlled, three-period crossover trial to investigate short-term effects of the dipeptidyl peptidase-4 inhibitor linagliptin on macro- and microvascular endothelial function in type 2 diabetes
Creators: name: Jax, Thomas
name: Stirban, Alin
name: Terjung, Arne
name: Esmaeili, Habib
name: Berk, Andreas
name: Thiemann, Sandra
name: Chilton, Robert
name: Eynatten, Maximilian
name: Marx, Nikolaus
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Additional file 1. Supplementary material.
Agenti (autonomi) normativi in società artificiali: uno studio simulativo sull'emergenza di artefatti sociali
Creators: name: CAMPENNI, MARCO
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: social simulation; normative architectures; norms; artificial intelligence; computational modeling
subject: social simulation
subject: normative architectures
subject: norms
subject: artificial intelligence
subject: computational modeling

description: 24. ciclo
Analysis of Bacterial Community Composition in Sediments of the Mainstream and Tributaries in the Wanzhou Section of the Three Gorges Reservoir Area, China
Creators: name: Wan, Peng
name: Qin, Yu
name: Li, Zhaoxia
name: Ouyang, Changyue
name: Zhang, Xi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: River ecosystems are intricately connected to the biogeochemical processes mediated by sediment bacterial communities. The Three Gorges Reservoir, a critical freshwater resource, has seen limited research on bacterial community composition, particularly in comparative studies between its mainstream and tributaries. High-throughput sequencing was utilized to examine bacterial diversity and community structure in the sediments of the Wanzhou section. The analysis uncovered significant spatiotemporal heterogeneity and revealed similar community structures between the mainstream and tributaries, with Proteobacteria, Actinobacteria, and Bacteroidetes as the predominant phyla. Although no significant phylum-level differences were observed among the top five dominant species, their relative abundances showed notable variations. These differences are attributed to the reservoir’s cyclical water storage and release, which alter nutrient concentrations and induce seasonal variations in bacterial communities. The intrinsic growth characteristics of microorganisms and their adaptive responses to environmental changes are identified as key factors influencing bacterial community differentiation. These insights enhance the understanding of bacterial dynamics in freshwater sediments and contribute to ecological assessments and environmental management in the Three Gorges Reservoir area.