cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines
Creators: name: McAnarney, Eileen T.
name: Waters, Katrina M.
name: Gralinski, Lisa E.
name: Yount Jr., Boyd L.
name: Dinnon III, Kenneth H.
name: Leist, Sarah R.
name: Graham, Rachel L.
name: Baric, Ralph S.
name: Menachery, Vineet D.
name: Mitchell, Hugh D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: With an ongoing threat posed by circulating zoonotic strains, new strategies are required to prepare for the next emergent coronavirus (CoV). Previously, groups had targeted conserved coronavirus proteins as a strategy to generate live attenuated vaccine strains against current and future CoVs. With this in mind, we explored whether manipulation of CoV NSP16, a conserved 2′O methyltransferase (MTase), could provide a broad attenuation platform against future emergent strains. Using the severe acute respiratory syndrome-CoV mouse model, an NSP16 mutant vaccine was evaluated for protection from heterologous challenge, efficacy in the aging host, and potential for reversion to pathogenesis. Despite some success, concerns for virulence in the aged and potential for reversion makes targeting NSP16 alone an untenable approach. However, combining a 2′O MTase mutation with a previously described CoV fidelity mutant produced a vaccine strain capable of protection from heterologous virus challenge, efficacy in aged mice, and no evidence for reversion. Together, the results indicate that targeting the CoV 2′O MTase in parallel with other conserved attenuating mutations may provide a platform strategy for rapidly generating live attenuated coronavirus vaccines.

IMPORTANCE Emergent coronaviruses remain a significant threat to global public health and rapid response vaccine platforms are needed to stem future outbreaks. However, failure of many previous CoV vaccine formulations has clearly highlighted the need to test efficacy under different conditions and especially in vulnerable populations such as the aged and immunocompromised. This study illustrates that despite success in young models, the 2′O methyltransferase mutant carries too much risk for pathogenesis and reversion in vulnerable models to be used as a stand-alone vaccine strategy. Importantly, the 2′O methyltransferase mutation can be paired with other attenuating approaches to provide robust protection from heterologous challenge and in vulnerable populations. Coupled with increased safety and reduced pathogenesis, the study highlights the potential for 2′O methyltransferase attenuation as a major component of future live attenuated coronavirus vaccines.
Photon self-interaction on deformed spacetime
Creators: name: Horvat, Raul
name: Trampetić, Josip
name: You, Jiangyang
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: A novel nonlocal four-photon interaction on the deformed spacetime is derived and studied in the three selected models (I, II, III). The first two models (I, II) are obtained via two distinct second-order $θ$-exact Seiberg-Witten maps of the noncommutative U(1) gauge field strength on Moyal space. The third one (III), inspired by the manifestly gauge invariant structures emerging in the first two, due to the model generality has been constructed with a different set of freedom parameters. The physical relevancy of all models is analyzed by evaluating the four-photon-tadpole diagram, which, when combined with the bubble graph, enables us to fully consider all contributions to the one-loop photon polarization tensor. For an arbitrary noncommutative matrix theta^μν, the full quadratic IR divergence cancellation in the one-loop photon two-point function is obtained with particular combinations of Seiberg-Witten map/gauge-symmetry freedom parameters in models I and II. Finally, our model III enables complete elimination of all pathological terms in the photon polarization tensor at one-loop order if a special value for the theta matrix is chosen.
description: 24 pages, 3 figures. Version published in Physical Review D 92, 125006 (2015). arXiv admin note: text overlap with arXiv:1506.02864
Plasmon spectrum and plasmon-mediated energy transfer in a multi-connected geometry
Creators: name: Shan, L.
name: Mishchenko, E. G.
name: Raikh, M. E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Surface plasmon spectrum of a metallic hyperbola can be found analytically with the separation of variables in elliptic coordinates. The spectrum consists of two branches: symmetric, low-frequency branch, $ωω_0/\sqrt{2}$, where $ω_0$ is the bulk plasmon frequency. The frequency width of the plasmon band increases with decreasing the angle between the asymptotes of the hyperbola. For the simplest multi-connected geometry of two hyperbolas separated by an air spacer the plasmon spectrum contains two low-frequency branches and two high-frequency branches. Most remarkably, the lower of two low-frequency branches exists at $ω\rightarrow 0$, i.e., unlike a single hyperbola, it is "thresholdless." We study how the complex structure of the plasmon spectrum affects the energy transfer between two emitters located on the surface of the same hyperbola and on the surfaces of different hyperbolas.
description: 11 pages, 10 figures
Ultrafast non‐linear 2D microspectroscopy reveals coherent phonon‐mediated intra‐ and intervalley exciton interaction in an individual SWCNT
Creators: name: Nuß, Matthias
name: Müller, Kerstin
name: Li, Donghai
name: Schöppler, Friedrich
name: Hertel, Tobias
name: Brixner, Tobias
Publisher: name: figshare
Year: 2023
Subjects: Physical chemistry not elsewhere classified
Surface properties of condensed matter
Nonlinear optics and spectroscopy
Molecular imaging (incl. electron microscopy and neutron diffraction)
Theoretical and computational chemistry not elsewhere classified
Thermodynamics and statistical physics

description: Further developments in molecular electronics, adressing SWCNTs, would benefit strongly from insights in the spatio‐temporal evolution of molecular processes. Ultrafast non‐linear techniques provide tracking of energy transfer pathways e.g., mediated via electron‐phonon coupling [1]. A comprehensive way to observe these dynamics is coherent 2D fluorescence microspectroscopy [2]. This method is a generalization of transient absorption spectroscopy with frequency‐resolved pump and probe steps, combined with spatially‐resolved optical microscopy. This provides, e.g., to observe the phonon‐mediated formation and annihilation dynamics of initially bright and dark‐state excitons due to the strong exciton‐phonon coupling on the femtosecond timescale. Here, we utilize the third‐order 2D signal for monitoring the trapped intra‐ and intervalley exciton interaction in a SWCNT [3,4]. To this end, an transform‐limitted LCD‐shaped four‐pulse sequence is focused on an (6,4) SWCNT and the fluorescence is detected as a function of inter‐pulse time delays and phases. [1] Graham, M. et al., Nano Lett. 12, 813–819 (2012). [2] Goetz, S. et al., Opt. Express 26, 3915–3925 (2018). [3] Secchi, A. et al., Phys. Rev. B 88 (2013). [4] Kislitsyn, D. et al., J. Phys. Chem. Lett. 5, 3138–3143 (2014).
Cosmic Muon Detector Using Proportional Chambers
Creators: name: Varga, Dezső
name: Gál, Zoltán
name: Hamar, Gergő
name: Molnár, Janka Sára
name: Oláh, Éva
name: Pázmándi, Péter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A set of classical multi-wire proportional chambers were designed and constructed with the main purpose of efficient cosmic muon detection. These detectors are relatively simple to construct, and at the same time are low cost, making them ideal for educational purposes. The detector layers have efficiencies above 99% for minimum ionizing cosmic muons, and their position resolution is about 1 cm, that is, particle trajectories are clearly observable. Visualization of straight tracks is possible using an LED array, with the discriminated and latched signal driving the display. Due to the exceptional operating stability of the chambers, the design can also be used for cosmic muon telescopes.
description: 11 pages, 11 figures. Submitted to the European Journal of Physics
Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice
Creators: name: Douglas, Madeline G.
name: Leist, Sarah R.
name: Baric, Ralph S.
name: Cockrell, Adam S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: The emergence of highly pathogenic human coronaviruses (hCoVs) in the last two decades has illuminated their potential to cause high morbidity and mortality in human populations and disrupt global economies. Global pandemic concerns stem from their high mortality rates, capacity for human-to-human spread by respiratory transmission, and complete lack of approved therapeutic countermeasures. Limiting disease may require the development of virus-directed and host-directed therapeutic strategies due to the acute etiology of hCoV infections. Therefore, understanding how hCoV-host interactions cause pathogenic outcomes relies upon mammalian models that closely recapitulate the pathogenesis of hCoVs in humans. Pragmatism has largely been the driving force underpinning mice as highly effective mammalian models for elucidating hCoV-host interactions that govern pathogenesis. Notably, tractable mouse genetics combined with hCoV reverse genetic systems has afforded the concomitant manipulation of virus and host genetics to evaluate virus-host interaction networks in disease. In addition to assessing etiologies of known hCoVs, mouse models have clinically predictive value as tools to appraise potential disease phenotypes associated with pre-emergent CoVs. Knowledge of CoV pathogenic potential before it crosses the species barrier into the human population provides a highly desirable preclinical platform for addressing global pathogen preparedness, an overarching directive of the World Health Organization. Although we recognize that results obtained in robust mouse models require evaluation in non-human primates, we focus this review on the current state of hCoV mouse models, their use as tractable complex genetic organisms for untangling complex hCoV-host interactions, and as pathogenesis models for preclinical evaluation of novel therapeutic interventions.
Development of Daphnia magna under exposure to the xenobiotic octylphenol
Creators: name: Dao, Thanh Son
name: Vo, Thi My Chi
name: Do, Hong Lan Chi
name: Nguyen, Phuoc Dan
Publisher: name: Journal of Vietnamese Environment
Year: 2014

description: Xenobiotics are of human and environmental concerns due to their potential toxicity. Octylphenol is one of the very common and daily used xenobiotics in door and out door activities of human beings. Toxicity of octylphenol to aquatic organisms, especially to zooplankton (e.g. Daphnia magna) was investigated but not fully understood. In this study we evaluated the chronic effects of octylphenol at the concentrations of 5, 50 and 500 µg L-1 on Daphnia magna over a period of 14 days. The results showed that low concentration of octylphenol (5 µg L-1) stimulated the maturation while high concentrations of the chemical (50 and 500 µg L-1) caused a significant mortality to the Daphnia. Besides, all the tested concentrations of octylphenol had serious impacts on fecundity and growth of the animals. Investigations on the presence, distribution, fate and toxicity of xonobiotics including octylphenol in the developing country environment are suggested for human, environmental and ecological health protection. Những hợp chất tổng hợp đang là mối quan ngại cho con người và môi trường vì khả năng gây độc của chúng. Octylphenol là một trong những hợp chất tổng hợp được sử dụng phổ biến và thường xuyên trong những hoạt động của con người trong nhà và ngoài trời. Độc tính của octylphenol đối với thủy sinh vật, đặc biệt đối với động vật phù du (vd. Daphnia magna) mặc dù đã được nghiên cứu nhưng vẫn chưa được hiểu biết đầy đủ. Trong nghiên cứu này, chúng tôi đánh giá ảnh hưởng mãn tính của octylphenol ở các nồng độ 5, 50 và 500 µg/lít lên Daphnia magna trong thời gian 14 ngày. Kết quả cho thấy ở nồng độ octylphenol thấp (5 µg/lít) kích thích sự thành thục của sinh vật trong khi ở nồng độ cao hơn (50 và 500 µg/lít) gây chết đáng kể Daphnia. Bên cạnh đó, tất cả các nồng độ ocytlphenol dùng trong thí nghiệm gây ảnh hưởng nghiêm trọng lên sức sinh sản và sinh trưởng của sinh vật. Nghiên cứu về sự hiện diện, phân bố, phát tán và độc tính của những chất tổng hợp bao gồm octylphenol ở các nước đang phát triển nên được tiến hành vì mục tiêu bảo vệ sức khỏe con người, môi trường và hệ sinh thái.
description: Journal of Vietnamese Environment, Vol 6 No 2 (2014)
Completeness on the worm domain and the Müntz-Szász problem for the Bergman space
Creators: name: Krantz, Steven G.
name: Peloso, Marco M.
name: Stoppato, Caterina
Publisher: name: arXiv
Year: 2015
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 32A36, 32T20

description: In this paper we are concerned with the problem of completeness in the Bergman space of the worm domain $\mathcal{W}_μ$ and its truncated version $\mathcal{W}'_μ$. We determine some orthogonal systems and show that they are not complete, while showing that the union of two particular of such systems is complete. In order to prove our completeness result we introduce the Muentz-Szasz problem for the 1-dimensional Bergman space of the disk $\{ζ: |ζ-1|<1\}$ and find a sufficient condition for its solution.
description: 14 pages, Author Accepted Manuscript
The effects of peer support in mental health services: a mini systematic review and analysis.
Creators: name: Blenman, Rebecca
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Psychiatric and Mental Health
subject: Medicine and Health Sciences
subject: Mental and Social Health
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: A research protocol for a mini systematic review of the effects of peer support in mental health services. This review focuses on how personal, social and recovery outcomes are affected by peer support in mental health services.
Excluding a full grid minor
Creators: name: Heuer, Karl
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: In this paper we characterise the graphs containing a $\mathbb{Z} \times \mathbb{Z}$ grid minor in a similar way as it has been done by Halin for graphs with an $\mathbb{N} \times \mathbb{Z}$ grid minor. Using our characterisation, we describe the structure of graphs without $\mathbb{Z} \times \mathbb{Z}$ grid minors in terms of tree-decompositions.
description: 11 pages, 2 figures; former formulation of $(ii)$ of Theorem 1.4 is now split into $(ii)$ and $(iii)$ to avoid misunderstanding
Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis
Creators: name: Whitmore, Alan
name: Morrison, Thomas E.
name: Jensen, Kara
name: Leist, Sarah R.
name: Menachery, Vineet D.
name: Baric, Ralph S.
name: Gralinski, Lisa E.
name: Heise, Mark T.
name: Sheahan, Timothy P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Acute respiratory distress syndrome (ARDS) is immune-driven pathologies that are observed in severe cases of severe acute respiratory syndrome coronavirus (SARS-CoV) infection. SARS-CoV emerged in 2002 to 2003 and led to a global outbreak of SARS. As with the outcome of human infection, intranasal infection of C57BL/6J mice with mouse-adapted SARS-CoV results in high-titer virus replication within the lung, induction of inflammatory cytokines and chemokines, and immune cell infiltration within the lung. Using this model, we investigated the role of the complement system during SARS-CoV infection. We observed activation of the complement cascade in the lung as early as day 1 following SARS-CoV infection. To test whether this activation contributed to protective or pathologic outcomes, we utilized mice deficient in C3 (C3–/–), the central component of the complement system. Relative to C57BL/6J control mice, SARS-CoV-infected C3–/– mice exhibited significantly less weight loss and less respiratory dysfunction despite equivalent viral loads in the lung. Significantly fewer neutrophils and inflammatory monocytes were present in the lungs of C3–/– mice than in C56BL/6J controls, and subsequent studies revealed reduced lung pathology and lower cytokine and chemokine levels in both the lungs and the sera of C3–/– mice than in controls. These studies identify the complement system as an important host mediator of SARS-CoV-induced disease and suggest that complement activation regulates a systemic proinflammatory response to SARS-CoV infection. Furthermore, these data suggest that SARS-CoV-mediated disease is largely immune driven and that inhibiting complement signaling after SARS-CoV infection might function as an effective immune therapeutic.

IMPORTANCE The complement system is a critical part of host defense to many bacterial, viral, and fungal infections. It works alongside pattern recognition receptors to stimulate host defense systems in advance of activation of the adaptive immune response. In this study, we directly test the role of complement in SARS-CoV pathogenesis using a mouse model and show that respiratory disease is significantly reduced in the absence of complement even though viral load is unchanged. Complement-deficient mice have reduced neutrophilia in their lungs and reduced systemic inflammation, consistent with the observation that SARS-CoV pathogenesis is an immune-driven disease. These data suggest that inhibition of complement signaling might be an effective treatment option following coronavirus infection.
EDUCAÇÃO À DISTÂNCIA COMO ESTRATÉGIA PARA QUALIFICAÇÃO EM SAÚDE: uma revisão de escopo
Creators: name: Rocha, Rodrigo
name: Dantas, Daniele
name: de Lima, Dhyanine
name: de Farias, Erica
name: Feitosa, Eva
name: Valença, Cecilia
name: da Silva, Jose
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences

description: Trata-se de uma revisão de escopo realizada em julho de 2020. O estudo objetiva identificar como a educação à distância pode contribuir para a qualificação dos profissionais de saúde. Neste sentido, a presente revisão justifica-se por fornecer um agregado de contribuições para os profissionais, no qual irá mostrar que a EaD possui altas taxas de positividade, uma vez que é vastamente utilizada pelos profissionais e estes relatam nos estudos como essa modalidade agregou em seus conhecimentos e na aplicabilidade em seus locais de trabalho e desta forma acabará por refletir em melhores ações nas unidades de saúde, como também irá fornecer contribuições aos pacientes e a toda comunidade acadêmica.
Basin resources management: simulating soil erosion risk by soil and water assessment tool (SWAT) in Ta Trach river watershed, central Vietnam
Creators: name: Nguyen, Bich Ngoc
name: Nguyen, Hoang Khanh Linh
Publisher: name: Journal of Vietnamese Environment
Year: 2014

description: Nowadays, one of the urgent issues in the management of river basin resources as land degradation, especially soil erosion risk occurs due to complex factors of climate, cultivation practices of human and impacting of the operation of socio-economic development taking place in the basin. Soil erosion has been considered as the primary cause of soil degradation since soil erosion leads to the loss of topsoil and soil organic matters, which are essential for the growing of plants. Ta Trach river watershed, is a mountainous basin lying to the West - South of Thua Thien Hue province, having complex terrain. The result of this study showed that the amount of sediment yield accounts for high percentage. The average annual sedimentation is 41.60 tones per hectometer in the period of 2005 to 2010, soil erosion were classified by 5 levels. In which, the less deleterious erosion level still occupies high percentage with more than 55 % of watershed area. The main area of less deleterious soil erosion was located at high topography and high slope. The area of deleterious soil erosion occupies percentage lower than 22.63% of the entire basin, but it is also a warning sign to the extent of land degradation taking place in the basin if the erosion rate increases in the future. Ngày nay, một trong những vấn đề cấp bách trong quản lý tài nguyên lưu vực sông là sự thoái hóa đất và đặc biệt là nguy cơ xói mòn đất xảy ra do yếu tố khí hậu phức tạp, phương thức canh tác của con người và tác động của những hoạt động phát triển kinh tế - xã hội đang diễn ra ở lưu vực. Lưu vực sông Tả Trạch là một lưu vực miền núi nằm về phía Tây - Nam của tỉnh Thừa Thiên Huế, có địa hình khá phức tạp. Mục tiêu của nghiên cứu này là ứng dụng công cụ SWAT để mô phỏng xói mòn đất ở lưu vực sông Tả Trạch thuộc tỉnh Thừa Thiên Huế từ năm 2005 đến năm 2010. Kết quả của nghiên cứu cho thấy lượng đất bồi lắng ở lưu vực chiếm tỷ lệ cao, trung bình mỗi năm bồi lắng 41.60 tấn/ha trong giai đoạn 2005 đến 2010, mức độ xói mòn được phân cấp thành 5 cấp xói mòn. Trong đó, mức độ xói mòn ít nguy hại chiếm ở tỷ lệ cao hơn 55 % diện tích lưu vực, chủ yếu phân bố ở những khu vực có địa hình cao, độ dốc lớn. Diện tích xói mòn nguy hại chiếm tỷ lệ thấp hơn 22,63% diện tích toàn lưu vực nhưng đây cũng là một dấu hiệu báo động cho mức độ thoái hóa đất diễn ra ở lưu vực trong tương lai nếu mức xói mòn này tăng lên.
description: Journal of Vietnamese Environment, Vol 6 No 2 (2014)
Shape Allophiles Improve Entropic Assembly
Creators: name: Harper, Eric S.
name: Marson, Ryan L.
name: Anderson, Joshua A.
name: van Anders, Greg
name: Glotzer, Sharon C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We investigate a class of "shape allophiles" that fit together like puzzle pieces as a method to access and stabilize desired structures by controlling directional entropic forces. Squares are cut into rectangular halves, which are shaped in an allophilic manner with the goal of re-assembling the squares while self-assembling the square lattice. We examine the assembly characteristics of this system via the potential of mean force and torque, and the fraction of particles that entropically bind. We generalize our findings and apply them to self-assemble triangles into a square lattice via allophilic shaping. Through these studies we show how shape allophiles can be useful in assembling and stabilizing desired phases with appropriate allophilic design.
description: 17 pages, 7 figures. Published as E. S. Harper, R. L. Marson, J. A. Anderson, G. van Anders, and S. C. Glotzer, Soft Matter, 2015, DOI: 10.1039/c5sm01351h
Growth control of sessile microbubbles in PDMS devices
Creators: name: Volk, Andreas
name: Rossi, Massimiliano
name: Kähler, Christian J.
name: Hilgenfeldt, Sascha
name: Marin, Alvaro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In a microfluidic environment, the presence of bubbles is often detrimental to the functionality of the device, leading to clogging or cavitation, but microbubbles can also be an indispensable asset in other applications such as microstreaming. In either case, it is crucial to understand and control the growth or shrinkage of these bodies of air, in particular in common soft-lithography devices based on polydimethylsiloxane (PDMS), which is highly permeable to gases. In this work, we study the gas transport into and out of a bubble positioned in a microfluidic device, taking into account the direct gas exchange through PDMS as well as the transport of gas through the liquid in the device. Hydrostatic pressure regulation allows for the quantitative control of growth, shrinkage, or the attainment of a stable equilibrium bubble size. We find that the vapor pressure of the liquid plays an important role for the balance of gas transport, accounting for variability in experimental conditions and suggesting additional means of bubble size control in applications.
description: 6 pages, supplementary information and cover included in ancillary files
Forest resources and forestry in Vietnam
Creators: name: Luong, Thi Hoan
Publisher: name: Journal of Vietnamese Environment
Year: 2014

description: Forest and forestland are important roles and sources of livelihood for the population living in or near forests and in mountainous areas of Vietnam. The objectives of this paper analysed the change in forest resource, and policy of forestry in Vietnam. In recent several years, forest area rapidly covered an average rate of 240,000 ha/year and had about 13.39 million hectares in 2010. It has contributed to the use of bare land, job creation and improvement of livelihoods for 25% of Vietnam’s population living in mountainous areas. Those results were the purpose of reforestation program and the production of wood industry in Vietnam. In this addition, government policies and regulations have provided a solid foundation for development of the forest plantations and conservation of forest ecosystems though forest land allocation and lease to organizations, households, and individuals. Therefore, the forest utilization has motivated by both environmental and commercial factors in Vietnam based on dividing into three forest categories special use, protection and production forests. However, the development strategy of forest management plan is the difficulties associated with conflicting land claims and boundary disputes due to the value of the established forest. Rừng và đất rừng đóng vai trò quan trọng và là nguồn sinh kế cho người dân sống trong hoặc gần rừng ở các khu vực miền núi của Việt Nam. Mục tiêu của nghiên cứu này phân tích sự thay đổi về tài nguyên rừng và chính sách về lâm nghiệp. Trong một vài năm gần đây, diện tích rừng bao phủ nhanh với tốc độ trung bình 240.000 ha/năm và có khoảng 13,39 triệu ha trong năm 2010 này đã góp phần vào việc sử dụng đất trống, tạo việc làm và cải thiện đời sống cho 25% dân số sống ở khu vực miền núi của Việt Nam. Kết quả này là mục đích của chương trình trồng rừng và sản xuất gỗ công nghiệp tại Việt Nam. Bên cạnh đó, chính sách và các quy định của chính phủ đã cung cấp một nền tảng vững chắc cho việc phát triển diện tích trồng rừng và bảo tồn hệ sinh thái rừng mặc dù rừng và đất rừng đã được giao và khoán cho các tổ chức, hộ gia đình, cá nhân. Vì vậy, việc sử dụng rừng đã thúc đẩy bởi hai yếu tố môi trường và thương mại ở Việt Nam, dựa trên phân loại rừng: rừng đặc dụng, rừng sản xuất và rừng phòng hộ. Tuy nhiên, chiến lược kế hoạch quản lý phát triển rừng có những khó khăn liên quan đến xung đột khiếu nại đất và tranh chấp biên giới do giá trị của rừng được thành lập.
description: Journal of Vietnamese Environment, Vol 6 No 2 (2014)
Root to Kellerer
Creators: name: Beiglböck, Mathias
name: Huesmann, Martin
name: Stebegg, Florian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: Primary 60G42, 60G44, Secondary 91G20

description: We revisit Kellerer's Theorem, that is, we show that for a family of real probability distributions $(μ_t)_{t\in [0,1]}$ which increases in convex order there exists a Markov martingale $(S_t)_{t\in[0,1]}$ s.t.\ $S_t\sim μ_t$. To establish the result, we observe that the set of martingale measures with given marginals carries a natural compact Polish topology. Based on a particular property of the martingale coupling associated to Root's embedding this allows for a relatively concise proof of Kellerer's theorem. We emphasize that many of our arguments are borrowed from Kellerer \cite{Ke72}, Lowther \cite{Lo07}, and Hirsch-Roynette-Profeta-Yor \cite{HiPr11,HiRo12}.
description: 8 pages, 1 figure
Pyrene degradation of biofilm-forming Paracoccus sp. DG25 isolated from oil polluted samples collected in petroleum storage Duc Giang, Hanoi
Creators: name: Le, Thi Nhi Cong
name: Cung, Thi Ngoc Mai
name: Vu, Thi Thanh
name: Nghiem, Ngoc Minh
name: Hoang, Phuong Ha
name: Do, Thi Lien
name: Do, Thi To Uyen
Publisher: name: Journal of Vietnamese Environment
Year: 2014

description: In this study, a well biofilm-forming bacterial strain was isolated from oil contaminated water and sediment samples collected in petroleum storage Duc Giang, Hanoi. It was identified as Paracoccus sp. DG25 and registered in the GenBank database with the accession numbers KJ608354. Several biophysical and bio-chemical conditions for the biofilm formation of the strain were estimated such as pH, temperature, carbon sources and nitrogen sources. As the results the biofilm forming capacity was highest at pH 7, 37 oC, on maltose and supplemented with KNO3. Using these optimal conditions, the formed biofilm degraded 76.07 % of pyrene after 7 day-incubation, with the initial concentration of 300 ppm by high-performance liquid chromatography (HPLC) analysis. To our knowledge, there is rare publication on pyrene degradation by biofilm-forming bacteria. Therefore, the obtained results show that biofilm formed the strain Paracoccus sp. DG25 may considerably increase the degrading efficiency of pyrene and may lead to a new approach to treat polycyclic aromatic hydrocarbons containing in petroleum oil contaminated water in Vietnam. Trong nghiên cứu này, từ các mẫu đất và nước nhiễm dầu lấy tại kho xăng Đức Giang, Hà Nội, chúng tôi đã phân lập được chủng vi khuẩn có khả năng tạo màng sinh học tốt. Chủng vi khuẩn này đã được phân loại và định tên là Paracoccus sp. DG25 với số đăng ký trên ngân hàng Gen là KJ608354. Chúng tôi cũng đã nghiên cứu một số điều kiện hóa lý ảnh hưởng tới khả năng hình thành màng sinh học như pH, nhiệt độ, nguồn Carbon và nguồn Nitơ. Kết quả cho thấy, chủng DG25 có khả năng tạo màng tốt nhất ở các điều kiện pH 7, 37 oC, nguồn Carbon là maltose và nguồn Nitơ là KNO3. Sử dụng các điều kiện tối ưu này để tạo màng và đánh giá khả năng phân hủy pyrene của màng tạo thành. Bằng phương pháp sắc ký lỏng cao áp, chúng tôi đã đánh giá được hàm lượng pyrene bị phân hủy sau 7 ngày nuôi tĩnh bởi màng sinh học của chủng DG25 lên tới 76,07 % với nồng độ ban đầu là 300 ppm. Cho tới nay, chưa có nhiều công bố về hiệu quả phân hủy pyrene của các chủng vi khuẩn tạo màng sinh học. Do vậy, kết quả đạt được này mở ra khả năng sử dụng màng tạo thành bởi chủng DG25 để nâng cao hiệu quả phân hủy pyren và có thể mở ra phương pháp mới nhằm xử lý các hợp chất hydrocarbon thơm có trong nước ô nhiễm dầu ở Việt Nam.
description: Journal of Vietnamese Environment, Vol 6 No 2 (2014)
Towards higher dimensional black rings
Creators: name: Chervonyi, Yuri
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Despite all attempts, exact solutions for black rings in more than five dimensions remain elusive. In this paper we clarify some of the reasons for that, in particular we show that a peculiar symmetry of the five--dimensional black ring - separability of the base - cannot occur in dimensions higher than five. We also construct supersymmetric solutions that have symmetries of 5D supersymmetric black ring and show that they do not have regular horizons.
description: 11 pages. V2: references added, several typos are fixed. V3: reference added. V4: typo is fixed, several comments added
Conservatives show reduced integration of disconfirmatory evidence in value-based learning
Creators: name: Najar, Anis
name: Chevallier, Coralie
name: Palminteri, Stefano
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: The computational origins of political attitudes remain elusive. This study investigates the possible relationship between value-based learning bias processes and political orientation. By combining factor analysis of political questionnaires and computational modelling of reinforcement learning behaviour, we found some evidence for a possible link between conservative political attitudes and reduced integration of disconfirmatory information in a representative sample of the French electorate. In this pre-registration, we report results obtained on an discovery sample (N=1533) of the full dataset. The same analysis will be reproduced on the remaining data, after preregistration of the preliminary results. The analyses are detailed in the draft attached to this project and include - factor analysis on political orientation questionnaires aimed - computational modelling of the reinforcement learning data - correlation between reinforcement learning parameters and political orientation factors We will replicate all the analyses in the discovery sample and calculate the meta-analytical p-values as a way to assess replicability.
The human sodium iodide symporter as a reporter gene for studying Middle East respiratory syndrome coronavirus pathogenesis
Creators: name: Cockrell, Adam S.
name: Kumar, Mia R.
name: Chefer, Svetlana
name: Baric, Ralph S.
name: Endlich-Fraiser, Ariel
name: Cooper, Kurt
name: Siedel, Jurgen
name: Sims, Amy
name: Johnson, Reed F.
name: Sharma, Heema
name: Yount, Boyd
name: Sayre, Philip J.
name: Jahrling, Peter B.
name: Bohannon, J. Kyle
name: Holbrook, Michael R.
name: Bartos, Christopher
name: Huzella, Louis M.
name: Thomasson, David
name: Lackemeyer, Matthew G.
name: Dyall, Julie
name: Posnikova, Elena
name: Hagen, Katie R.
name: Solomon, Jeffrey
name: Liu, David X.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Single photon emission computed tomography (SPECT) is frequently used in oncology and cardiology to evaluate disease progression and/or treatment efficacy. Such technology allows for real-time evaluation of disease progression and when applied to studying infectious diseases may provide insight into pathogenesis. Insertion of a SPECT-compatible reporter gene into a virus may provide insight into mechanisms of pathogenesis and viral tropism. The human sodium iodide symporter (hNIS), a SPECT and positron emission tomography reporter gene, was inserted into Middle East respiratory syndrome coronavirus (MERS-CoV), a recently emerged virus that can cause severe respiratory disease and death in afflicted humans to obtain a quantifiable and sensitive marker for viral replication to further MERS-CoV animal model development. The recombinant virus was evaluated for fitness, stability, and reporter gene functionality. The recombinant and parental viruses demonstrated equal fitness in terms of peak titer and replication kinetics, were stable for up to six in vitro passages, and were functional. Further in vivo evaluation indicated variable stability, but resolution limits hampered in vivo functional evaluation. These data support the further development of hNIS for monitoring infection in animal models of viral disease.IMPORTANCE Advanced medical imaging such as single photon emission computed tomography with computed tomography (SPECT/CT) enhances fields such as oncology and cardiology. Application of SPECT/CT, magnetic resonance imaging, and positron emission tomography to infectious disease may enhance pathogenesis studies and provide alternate biomarkers of disease progression. The experiments described in this article focus on insertion of a SPECT/CT-compatible reporter gene into MERS-CoV to demonstrate that a functional SPECT/CT reporter gene can be inserted into a virus.
Effect of machining, bur adjustments and hydrofluoric acid etching on the roughness and on the flexural strength of CAD/CAM glass-ceramics: a systematic review and meta-analyses
Creators: name: May, Michele
name: Fraga, Sara
name: May, Liliana
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Dental Materials
subject: Biomaterials
subject: Medicine and Health Sciences
subject: Dentistry
subject: FOS: Clinical medicine
subject: Engineering
subject: Biomedical Engineering and Bioengineering

description: Systematic review and meta-analyses of CAD/CAM glass-ceramics in vitro studies
Current-voltage characteristics of seven-helix proteins from a cubic array of amino acids
Creators: name: Alfinito, Eleonora
name: Reggiani, Lino
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Biological Physics (physics.bio-ph)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The electrical properties of a set of seven-helix transmembrane proteins, whose space arrangement (3D structure) is known, are investigated by using regular arrays of the amino acids. These structures, specifically cubes, have topological features similar to those shown by the chosen proteins. The theoretical results show a good agreement between the predicted current-voltage characteristics obtained from a cubic array and those obtained from a detailed 3D structure. The agreement is confirmed by available experiments on bacteriorhodopsin. Furthermore, all the analyzed proteins are found to share the same critical behaviour of the voltage-dependent conductance and of its variance. In particular, the cubic arrangement evidences a short plateau of the excess conductance and its variance at high voltages. The results of the present investigation show the possibility to predict the I-V characteristics of multiple-protein sample even in the absence of a detailed knowledge of their 3D structure.
description: 5 pages, 7 figures
MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape
Creators: name: Webb-Robertson, Bobbie-Jo M.
name: Nicora, Carrie D.
name: Metz, Thomas O.
name: Smith, Richard D.
name: Weitz, Karl K.
name: Casey, Cameron P.
name: Menachery, Vineet D.
name: Purvine, Samuel O.
name: Waters, Katrina M.
name: Schäfer, Alexandra
name: Monroe, Matthew E.
name: Walters, Kevin B.
name: Mitchell, Hugh D.
name: Gralinski, Lisa E.
name: Eisfeld, Amie J.
name: Burnum-Johnson, Kristin E.
name: Kawaoka, Yoshihiro
name: Baric, Ralph S.
name: Stratton, Kelly G.
name: Sims, Amy C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: Convergent evolution dictates that diverse groups of viruses will target both similar and distinct host pathways to manipulate the immune response and improve infection. In this study, we sought to leverage this uneven viral antagonism to identify critical host factors that govern disease outcome. Utilizing a systems-based approach, we examined differential regulation of IFN-γ–dependent genes following infection with robust respiratory viruses including influenza viruses [A/influenza/Vietnam/1203/2004 (H5N1-VN1203) and A/influenza/California/04/2009 (H1N1-CA04)] and coronaviruses [severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV)]. Categorizing by function, we observed down-regulation of gene expression associated with antigen presentation following both H5N1-VN1203 and MERS-CoV infection. Further examination revealed global down-regulation of antigen-presentation gene expression, which was confirmed by proteomics for both H5N1-VN1203 and MERS-CoV infection. Importantly, epigenetic analysis suggested that DNA methylation, rather than histone modification, plays a crucial role in MERS-CoV–mediated antagonism of antigen-presentation gene expression; in contrast, H5N1-VN1203 likely utilizes a combination of epigenetic mechanisms to target antigen presentation. Together, the results indicate a common mechanism utilized by H5N1-VN1203 and MERS-CoV to modulate antigen presentation and the host adaptive immune response.
Study on the distribution characteristics of the vegetation in high elevations in Hoang Lien National Park of Vietnam
Creators: name: Kieu, Quoc Lap
name: Nguyen, Tien Thanh
Publisher: name: Journal of Vietnamese Environment
Year: 2014

description: Hoang Lien National Park has a total area of 68569ha, located at an altitude of above sea 1000-3000m in the territory of the two provinces of Lai Chau and Lao Cai in Vietnam. It has a diversity of flora with 3252 species (including 775 endemic species and 236 endangered species), belonging to 1126 genera, 230 families and 6 different divisions. Due to the mountainous terrain, division diversity of Hoang Lien National Park’s vegetation is thus clearly characterized by high elevations. We have studied the distribution characteristics of the vegetation by high elevations in Hoang Lien National Park of Vietnam by the general survey methodology, fieldwork, remote sensing digital image processing and analysis and inheriting the preceding research results. The study results indicated the divisions in quantity, vegetation composition, especially differentiation of endemic and rare species in accordance with high elevations. Study results were preliminary used to suggest some orientations for preserving plant diversity in high elevations of the terrain. Vườn quốc gia Hoàng Liên có tổng diện tích 68569ha, nằm ở độ cao từ 1000-3000m so với mặt biển thuộc lãnh thổ hai tỉnh Lai Châu và Lào Cai của Việt Nam. Hệ thực vật của Vườn quốc gia Hoàng Liên rất phong phú với 3252 loài (trong đó có 775 loài đặc hữu và 236 loài quý hiếm), thuộc 1126 chi, 230 họ và 6 ngành khác nhau. Do địa hình núi cao, phân hóa đa dạng nên thảm thực vật của Vườn quốc gia Hoàng Liên có đặc trưng phân hóa theo đai cao rất rõ nét. Bằng các phương pháp điều tra tổng hợp, khảo sát thực địa, xử lí phân tích ảnh viễn thám và kế thừa các kết quả nghiên cứu đi trước nhóm tác giả đã tiến hành nghiên cứu đặc điểm phân bố thảm thực vật theo đai cao tại Vườn quốc gia Hoàng Liên của Việt Nam. Kết quả nghiên cứu chỉ rõ sự phân hoá về số lượng, thành phần hệ thực vật theo đai cao và phân hóa thành phần loài đặc hữu và quý hiếm theo đai cao. Bước đầu nghiên cứu đề xuất một vài định hướng bảo tồn đa dạng thực vật theo đai cao của địa hình.
description: Journal of Vietnamese Environment, Vol 6 No 2 (2014)
A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques
Creators: name: Johnson, Joshua C.
name: Hart, Randy
name: Liu, David X.
name: Cockrell, Adam S.
name: Moore, Ian N.
name: Bock, Kevin W.
name: Baric, Ralph S.
name: Bartos, Christopher
name: Graham, Rachel L.
name: Torzewski, Lisa
name: Johnson, Reed F.
name: Douglas, Madeline G.
name: Solomon, Jeffrey
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: The recurrence of new human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the need for effective therapeutic countermeasures. Nonhuman primate models are considered the gold standard for preclinical evaluation of therapeutic countermeasures. However, MERS-CoV-induced severe respiratory disease in humans is associated with high viral loads in the lower respiratory tract, which may be difficult to achieve in nonhuman primate models. Considering this limitation, we wanted to ascertain the effectiveness of using a MERS-CoV infectious clone (icMERS-0) previously shown to replicate to higher titers than the wild-type EMC 2012 strain. We observed respiratory disease resulting from exposure to the icMERS-0 strain as measured by CT in rhesus monkeys with concomitant detection of virus antigen by immunohistochemistry. Overall, respiratory disease was mild and transient, resolving by day 30 post-infection. Although pulmonary disease was mild, these results demonstrate for the first time the utility of CT imaging to measure disease elicited by a MERS-CoV infectious clone system in nonhuman primate models.
Dowd & Golomb: Object-feature binding survives dynamic shifts of spatial attention
Creators: name: Dowd, Emma
name: Golomb, Julie
Publisher: name: Open Science Framework
Year: 2022

description: Materials from Dowd & Golomb (2019, Psychological Science): "Object-feature binding survives dynamic shifts of spatial attention." Includes de-identified data sets for Experiments 1 and 2, as well as custom MATLAB scripts for modeling joint-feature distributions using MemToolbox (Suchow, Brady, Fougnie, & Alvarez, 2013). Please contact emma.wu.dowd@austin.utexas.edu with questions.
Comparative Analysis of customer's perception of Service quality in two selected Insurance companies
Creators: name: Dawit Begashaw
Publisher: name: Zenodo
Year: 2015

description: This exploratory study seeks to assess customers’ perception of service quality in the insurance sector in Ethiopia. The study involves two insurance companies. The SERVQUAL model was used to determine customers’ perception of service quality at each of the the insurers. The findings reveal that the customers’ expectations are not met.EIC has higher average negative gap scores for all dimensions.Reliability,Responsiveness and Empathy have higher negative gap score than NIC while tangibility and Assurance has higher negative score in NIC than EIC Both companies should take key strategic measures such as strategic human resource management ,application of latest technology and advanced management system so that positive dimensions in all attributes can be obtained.
Relationship of macroinvertebrate species and mangrove species in Xuan Thuy National Park, Vietnam
Creators: name: Haneji, Choshin
name: Do, Van Tu
name: Nguyen, The Cuong
name: Tran, Thi Phuong Anh
Publisher: name: Journal of Vietnamese Environment
Year: 2014

description: Associative relationships among mangrove species and macroinvertebrate species were analysed for ecosystems of Xuan Thuy National Park. Census of mangrove species with allometric measurements was conducted in selected plots, and census of macroinvertebrate species was conducted in quadrats inside of mangrove species census plots. Correlational analysis among allometrically estimated aboveground biomass of mangrove species and population of macroinvertebrate species was examined by clustering method. High level of similarity was resulted for specific macroinvertebrate species with specific mangrove species in annual and seasonal basis. Moreover, indicator macroinvertebrate species is proposed based on indicator value index method. Các mối quan hệ giữa thực vật ngập mặn và động vật không xương sống cỡ lớn được phân tích trong các hệ sinh thái của Vườn quốc gia Xuân Thủy. Khảo sát về số lượng của các loài cây ngập mặn cùng với các phép đo tương quan sinh trưởng được tiến hành trong các ô tiêu chuẩn, và nghiên cứu về thành phần loài và mật độ động vật không xương sống cỡ lớn được thực hiện trong các ô tiêu chuẩn này. Phân tích tương quan giữa sinh khối ước tính trên mặt đất của các loài cây ngập mặn và các quần thể động vật không xương sống cỡ lớn đã được thực hiện bằng phương pháp nhóm. Giữa các loài động vật không xương sống cỡ lớn đặc trưng với các loài cây ngập mặn đặc trưng đã cho thấy mức độ tương đồng cao theo năm và theo mùa. Hơn thế nữa, các loài động vật không xương sống cỡ lớn chỉ thị được đề xuất dựa trên phương pháp chỉ số giá trị chỉ thị.
description: Journal of Vietnamese Environment, Vol 6 No 2 (2014)