cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A sub-Neptune planet around TOI-1695 discovered and characterized with SPIRou and TESS
Creators: name: Kiefer, F.
name: Hébrard, G.
name: Martioli, E.
name: Artigau, E.
name: Doyon, R.
name: Donati, J. -F.
name: Cadieux, C.
name: Carmona, A.
name: Ciardi, D. R.
name: Cristofari, P. I.
name: de Almeida, L.
name: Figueira, P.
name: Gaidos, E.
name: Gonzales, E.
name: Lecavelier, A.
name: Stassun, K. G.
name: Arnold, L.
name: Benneke, B.
name: Boisse, I.
name: Bonfils, X.
name: Cook, N. J.
name: Cortés-Zuleta, P.
name: Delfosse, X.
name: Nascimento, J. Dias do
name: Fausnaugh, M.
name: Fong, W.
name: Fouqué, P.
name: Forveille, T.
name: da Silva, J. Gomes
name: Hesse, K.
name: Kóspál, Á.
name: Lewis, H.
name: Liu, C. -F.
name: Martins, J. H. C.
name: Paegert, M.
name: Seager, S.
name: Shang, H.
name: Twicken, J. D.
name: Vandal, T.
name: Vinatier, S.
name: Widemann, T.
name: Winn, J. N.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: TOI-1695 is a V-mag=13 M-dwarf star from the northern hemisphere at 45$\,$pc from the Sun, around which a 3.134-day periodic transit signal from a super-Earth candidate was identified in TESS photometry. With a transit depth of 1.3$\,$mmag, the radius of candidate TOI-1695.01 was estimated by the TESS pipeline to be 1.82$\,$R$_\oplus$ with an equilibrium temperature of $\sim 620\,$K. We successfully detect a reflex motion of the star and establish it is due to a planetary companion at an orbital period consistent with the photometric transit period thanks to a year-long radial-velocity monitoring of TOI-1695 by the SPIRou infrared spectropolarimeter. We use and compare different methods to reduce and analyse those data. We report a 5.5-$σ$ detection of the planetary signal, giving a mass of $5.5 \pm 1.0\,$M$_\oplus$ and a radius of $2.03 \pm 0.18\,$R$_\oplus$. We derive a mean equilibrium planet temperature of $590 \pm 90\,$K. The mean density of this small planet of $3.6 \pm 1.1\,$g$\,$cm$^{-3}$ is similar (1.7-$σ$ lower) than that of the Earth. It leads to a non-negligible fraction of volatiles in its atmosphere with $f_{H,He}=0.28^{+0.46}_{-0.23}$% or $f_\text{water}=23 \pm 12$%. TOI-1695$\,$b is a new sub-Neptune planet at the border of the M-dwarf radius valley that can help test formation scenarios for super-Earth/sub-Neptune-like planets.
description: 15 pages (+9 appendix pages), 19 figures, 8 tables, accepted for publication in A&A
Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
Creators: name: McNamara, James
name: Long, S. Alice
name: Ehlers, Mario R.
name: Fitzgibbon, Margret L.
name: Phippard, Deborah
name: Gottlieb, Peter A.
name: Soppe, Carol L.
name: Raskin, Philip
name: DiMeglio, Linda A.
name: Felner, Eric I.
name: Lim, Noha
name: Greenbaum, Carla J.
name: Dostou, Jean M.
name: Willi, Steven M.
name: Nepom, Gerald T.
name: Griffin, Kurt J.
name: Keyes-Elstein, Lynette
name: Rendell, Marc S.
name: Gitelman, Stephen E.
name: Sherry, Nicole A.
name: Tsalikian, Eva
name: Harris, Kristina M.
name: Moore, Wayne V.
name: Rigby, Mark R.
name: Pinckney, Ashley
name: Monzavi, Roshanak
name: Kanaparthi, Sai
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BACKGROUND. Type 1 diabetes (T1D) results from destruction of pancreatic β cells by autoreactive effector T cells. We hypothesized that the immunomodulatory drug alefacept would result in targeted quantitative and qualitative changes in effector T cells and prolonged preservation of endogenous insulin secretion by the remaining β cells in patients with newly diagnosed T1D.
Matriklens udvidelse - ændringer i ejendomsprocessen
Creators: name: Jensen, Bent Hulegaard
name: Mouritsen, Anne Kristine
Publisher: name: Geoforum Perspektiv
Year: 2018

description: Nærværende artikel har fokus på de kommende ændringer i ejendomsdannelsen. Ændringerne får en række konsekvenser for de centrale aktører i ejendomsdannelses-processen; kommunerne, Tinglysningsretten, Geodatastyrelsen samt de praktiserende landinspektører. Baggrunden for ændringerne bygger på de målsætninger, der er opstillet i Grund dataprogrammet og herunder delprogrammet for ejendomsdata, iværksat af Digitaliseringsstyrelsen. Implementering af programmet ledes af Styrelsen for Dataforsyning og Eff ektivisering og udmøntes igennem et samarbejde mellem Kommunernes Landsforening, Domstolsstyrelsen og Geodatastyrelsen.
description: Geoforum Perspektiv, Vol 16 No 30 (2017): Special issue related to the yearly conference, Kortdage
BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis
Creators: name: Wang, Mei-Lun
name: Wang, Jun
name: Liu, Kuancan
name: Dellon, Evan S.
name: Que, Jianwen
name: Jiang, Ming
name: Katzka, David A.
name: Nakagawa, Hiroshi
name: Ku, Wei-Yao
name: Lan, Xiaopeng
name: Falk, Gary W.
name: Zhou, Zhongren
name: Peters, Jeffrey H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Tissue homeostasis requires balanced self-renewal and differentiation of stem/progenitor cells, especially in tissues that are constantly replenished like the esophagus. Disruption of this balance is associated with pathological conditions, including eosinophilic esophagitis (EoE), in which basal progenitor cells become hyperplastic upon proinflammatory stimulation. However, how basal cells respond to the inflammatory environment at the molecular level remains undetermined. We previously reported that the bone morphogenetic protein (BMP) signaling pathway is critical for epithelial morphogenesis in the embryonic esophagus. Here, we address how this pathway regulates tissue homeostasis and EoE development in the adult esophagus. BMP signaling was specifically activated in differentiated squamous epithelium, but not in basal progenitor cells, which express the BMP antagonist follistatin. Previous reports indicate that increased BMP activity promotes Barrett’s intestinal differentiation; however, in mice, basal progenitor cell–specific expression of constitutively active BMP promoted squamous differentiation. Moreover, BMP activation increased intracellular ROS levels, initiating an NRF2-mediated oxidative response during basal progenitor cell differentiation. In both a mouse EoE model and human biopsies, reduced squamous differentiation was associated with high levels of follistatin and disrupted BMP/NRF2 pathways. We therefore propose a model in which normal squamous differentiation of basal progenitor cells is mediated by BMP-driven NRF2 activation and basal cell hyperplasia is promoted by disruption of BMP signaling in EoE.
NuSTAR Observations of the Magnetar 1E 2259+586
Creators: name: Vogel, Julia K.
name: Hascoet, Romain
name: Kaspi, Victoria M.
name: An, Hongjun
name: Archibald, Robert
name: Beloborodov, Andrei M.
name: Boggs, Steven E.
name: Christensen, Finn E.
name: Craig, William W.
name: Gotthelf, Eric V.
name: Grefenstette, Brian W.
name: Hailey, Charles J.
name: Harrison, Fiona A.
name: Kennea, Jamie A.
name: Madsen, Kristin K.
name: Pivovaroff, Michael J.
name: Stern, Daniel
name: Zhang, William W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report on new broad band spectral and temporal observations of the magnetar 1E 2259+586, which is located in the supernova remnant CTB 109. Our data were obtained simultaneously with the Nuclear Spectroscopic Telescope Array (NuSTAR) and Swift, and cover the energy range from 0.5-79 keV. We present pulse profiles in various energy bands and compare them to previous RXTE results. The NuSTAR data show pulsations above 20 keV for the first time and we report evidence that one of the pulses in the double-peaked pulse profile shifts position with energy. The pulsed fraction of the magnetar is shown to increase strongly with energy. Our spectral analysis reveals that the soft X-ray spectrum is well characterized by an absorbed double-blackbody or blackbody plus power-law model in agreement with previous reports. Our new hard X-ray data, however, suggests that an additional component, such as a power-law, is needed to describe the NuSTAR and Swift spectrum. We also fit the data with the recently developed coronal outflow model by Beloborodov for hard X-ray emission from magnetars. The outflow from a ring on the magnetar surface is statistically preferred over outflow from a polar cap.
description: 37 pages, 9 figures, corresponding author, vogel9@llnl.gov
Ginzburg-Landau Description and Emergent Supersymmetry of the $(3,8)$ Minimal Model
Creators: name: Klebanov, Igor R.
name: Narovlansky, Vladimir
name: Sun, Zimo
name: Tarnopolsky, Grigory
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A pair of the 2D non-unitary minimal models $M(2,5)$ is known to be equivalent to a variant of the $M(3,10)$ minimal model. We discuss the RG flow from this model to another non-unitary minimal model, $M(3,8)$. This provides new evidence for its previously proposed Ginzburg-Landau description, which is a $\mathbb{Z}_2$ symmetric theory of two scalar fields with cubic interactions. We also point out that $M(3,8)$ is equivalent to the $(2,8)$ superconformal minimal model with the diagonal modular invariant. Using the 5-loop results for theories of scalar fields with cubic interactions, we exhibit the $6-ε$ expansions of the dimensions of various operators. Their extrapolations are in quite good agreement with the exact results in 2D. We also use them to approximate the scaling dimensions in $d=3,4,5$ for the theories in the $M(3,8)$ universality class.
description: 24 pages, 2 figures; v3: additional symmetry constraints pointed out, references added
Dissociation of locomotor and cerebellar deficits in a murine Angelman syndrome model
Creators: name: Schonewille, Martijn
name: Aronica, Eleonora M.A.
name: Hoebeek, Freek E.
name: Gao, Zhenyu
name: Philpot, Benjamin D.
name: van Woerden, Geeske M.
name: Judson, Matthew C.
name: Bruinsma, Caroline F.
name: Elgersma, Ype
name: De Zeeuw, Chris I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Angelman syndrome (AS) is a severe neurological disorder that is associated with prominent movement and balance impairments that are widely considered to be due to defects of cerebellar origin. Here, using the cerebellar-specific vestibulo-ocular reflex (VOR) paradigm, we determined that cerebellar function is only mildly impaired in the Ube3am–/p+ mouse model of AS. VOR phase-reversal learning was singularly impaired in these animals and correlated with reduced tonic inhibition between Golgi cells and granule cells. Purkinje cell physiology, in contrast, was normal in AS mice as shown by synaptic plasticity and spontaneous firing properties that resembled those of controls. Accordingly, neither VOR phase-reversal learning nor locomotion was impaired following selective deletion of Ube3a in Purkinje cells. However, genetic normalization of αCaMKII inhibitory phosphorylation fully rescued locomotor deficits despite failing to improve cerebellar learning in AS mice, suggesting extracerebellar circuit involvement in locomotor learning. We confirmed this hypothesis through cerebellum-specific reinstatement of Ube3a, which ameliorated cerebellar learning deficits but did not rescue locomotor deficits. This double dissociation of locomotion and cerebellar phenotypes strongly suggests that the locomotor deficits of AS mice do not arise from impaired cerebellar cortex function. Our results provide important insights into the etiology of the motor deficits associated with AS.
Quantum Field Theories with Tensor Renormalization Group
Creators: name: Akiyama, Shinichiro
name: Kuramashi, Yoshinobu
name: Yoshimura, Yusuke
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We report recent progress on the application of the tensor renormalization group (TRG) to quantum field theories pursued by the Tsukuba group. We explain how to treat the scalar, fermion, and gauge theories with the TRG method presenting the results for the phase transitions in the (3+1)-dimensional ((3+1)$d$) complex $ϕ^4$ theory at finite density, (1+1)$d$ pure U(1) lattice gauge theory with a $θ$ term, (3+1)$d$ Nambu--Jona-Lasinio model at finite density and (1+1)$d$ and (2+1)$d$ Hubbard models at an arbitrary chemical potential. It is demonstrated that the TRG method is free from the sign problem in practical calculations and applicable to the four-dimensional models.
description: 25 pages, 20 figures, Proceedings of the 38th International Symposium on Lattice Field Theory, LATTICE2021 26th-30th July 2021, Zoom/Gather@Massachusetts Institute of Technology
GIS-baseret havplanlægning i Østersøregionen
Creators: name: Schrøder, Lise
name: Hansen, Henning Sten
Publisher: name: Geoforum Perspektiv
Year: 2018

description: Indenfor de seneste årtier er der en langt mere omfattende udnyttelse af havets ressourcer og et særligt fokus på vækstpotentialet i den ”blå økonomi”. Samtidig er der en erkendelse af behovet for en mere helhedsorienteret håndtering og planlægning af den menneskelige aktivitet, som påvirker det marine miljø og dets økosystemer. Danmark skal senest i 2021 have sin første havplan klar. En forudsætning er i den sammenhæng, at der fi ndes egnede planlægningsværktøjer, og at der er adgang til data - også på tværs af lande grænser. Her præsenteres de foreløbige resultater fra igangværende EU-projekter samt brugen af GIS-værktøjer i forbindelse med havplanlægning i Østersøen.
description: Geoforum Perspektiv, Vol 16 No 30 (2017): Special issue related to the yearly conference, Kortdage
Phase transitions in porous media
Creators: name: Gavioli, Chiara
name: Krejci, Pavel
Publisher: name: arXiv
Year: 2021
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 74F10, 76S05, 47J40, 35A01

description: The full quasistatic thermomechanical system of PDEs, describing water diffusion with the possibility of freezing and melting in a visco-elasto-plastic porous solid, is studied in detail under the hypothesis that the pressure-saturation hysteresis relation is given in terms of the Preisach hysteresis operator. The resulting system of balance equations for mass, momentum, and energy coupled with the phase dynamics equation is shown to admit a global solution under general assumptions on the data.
description: 52 pages
Dual-Affinity Re-Targeting proteins direct T cell–mediated cytolysis of latently HIV-infected cells
Creators: name: Lam, Chia-Ying Kao
name: Liu, Liqin
name: Gay, Cynthia L.
name: Kirchherr, Jennifer
name: Koenig, Scott
name: Parks, Robert
name: Sung, Julia A.M.
name: Soderberg, Kelly
name: Ferrari, Guido
name: Montefiori, David
name: Kuruc, JoAnn D.
name: Johnson, Syd
name: Garrido, Carolina
name: Ochsenbauer, Christina
name: Pollara, Justin
name: Allard, Brigitte
name: Nordstrom, Jeffrey L.
name: Cohen, Myron S.
name: LaBranche, Celia
name: Pickeral, Joy
name: Liao, Hua-Xin
name: Moore, Paul
name: Bonsignori, Mattia
name: Stanfield-Oakley, Sherry A.
name: Haynes, Barton F.
name: Yang, Yinhua
name: Archin, Nancie
name: Moody, M. Anthony
name: Margolis, David M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Enhancement of HIV-specific immunity is likely required to eliminate latent HIV infection. Here, we have developed an immunotherapeutic modality aimed to improve T cell–mediated clearance of HIV-1–infected cells. Specifically, we employed Dual-Affinity Re-Targeting (DART) proteins, which are bispecific, antibody-based molecules that can bind 2 distinct cell-surface molecules simultaneously. We designed DARTs with a monovalent HIV-1 envelope-binding (Env-binding) arm that was derived from broadly binding, antibody-dependent cellular cytotoxicity–mediating antibodies known to bind to HIV-infected target cells coupled to a monovalent CD3 binding arm designed to engage cytolytic effector T cells (referred to as HIVxCD3 DARTs). Thus, these DARTs redirected polyclonal T cells to specifically engage with and kill Env-expressing cells, including CD4+ T cells infected with different HIV-1 subtypes, thereby obviating the requirement for HIV-specific immunity. Using lymphocytes from patients on suppressive antiretroviral therapy (ART), we demonstrated that DARTs mediate CD8+ T cell clearance of CD4+ T cells that are superinfected with the HIV-1 strain JR-CSF or infected with autologous reservoir viruses isolated from HIV-infected–patient resting CD4+ T cells. Moreover, DARTs mediated CD8+ T cell clearance of HIV from resting CD4+ T cell cultures following induction of latent virus expression. Combined with HIV latency reversing agents, HIVxCD3 DARTs have the potential to be effective immunotherapeutic agents to clear latent HIV-1 reservoirs in HIV-infected individuals.
Sanktionen in der wirtschaftlichen Sozialhilfe – Auswirkungen auf die Beratungsbeziehung zwischen Sozialarbeitenden und Klient:innen und deren Motivation: Welche Handlungsempfehlungen ergeben sich für die Praxis?
Creators: name: Mitrovic, Melanie
Publisher: name: Hochschule Luzern – Soziale Arbeit
Year: 2024

description: Diese Arbeit untersucht die wirtschaftliche Sozialhilfe und deren Sanktionen sowie deren Einfluss auf die Beratungsbeziehung und Motivation der Klient:innen. Begründet wird dieser Fokus dadurch, dass in allen Tätigkeitsfeldern der Sozialen Arbeit die Beratungsbeziehung sowie die Motivation bedeutsam sein kann und als Schlüsselfaktor für nachhaltige Veränderung betrachtet werden kann. Die vorliegende Arbeit zeigt auf, welche Einflussfaktoren eine Beratungsbeziehung und Motivation tangieren. Hier werden die Rolle und die Bedeutung der Beratungsbeziehung, Faktoren wie Nähe und Distanz sowie der Motivationsbegriff und dessen Einflussfaktoren untersucht. Es werden die Auswirkungen von Sanktionen unteranderem auf die Beratungsbeziehung, Kommunikationsvariablen, Eigenverantwortung und extrinsische Motivation der Klient:innen analysiert.

Abschliessend werden praxisrelevante Handlungsempfehlungen mit klaren Anleitungen, Ansätzen und Techniken vorgestellt, darunter das Beziehungskonzept nach Schäfter, Beziehungsangebote nach Grawe, die motivierende Gesprächsführung nach Miller und Rollnick sowie Zielvereinbarungen nach Zobrist und Kähler.
description: + Code Diss LU: hslusa basa be + Fussnote: Bachelor-Arbeit, Hochschule Luzern – Soziale Arbeit, Studienrichtung Sozialarbeit, 2024 + NL-Code: NLLUHSA202409
Spin wave diffraction model for perpendicularly magnetized films
Creators: name: Vlaminck, V.
name: Temdie, L.
name: Castel, V.
name: Jungfleisch, M. B.
name: Stoeffler, D.
name: Henry, Y.
name: Bailleul, M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: We present a near-field diffraction model for spin waves in perpendicularly magnetized films applicable in any geometries of excitation fields. This model relies on Kalinikos-Slavin formalism to express the dynamic susceptibility tensor in k-space, and calculate the diffraction patterns via inverse 2D-Fourier transform of the response functions. We show an excellent quantitative agreement between our model and MuMax3 micro-magnetic simulations on two different geometries of antennas. Our method benchmarks spin wave diffraction in perpendicularly magnetized films, and is readily applicable for future designs of magnon beamforming and interferometric devices.
description: submitted to Journal of Applied Physics
The CLIC potential for new physics
Creators: name: Klamka, Jan
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The Compact Linear Collider (CLIC) is a mature option for a future electron-positron collider operating at centre-of-mass energies of up to 3 TeV. It incorporates a novel two-beam acceleration technique offering accelerating gradient of up to 100 MeV/m. CLIC would be built and operated in a staged approach with three centre-of-mass energy stages currently assumed to be 380 GeV, 1.5 TeV, and 3 TeV. The first CLIC stage will be focused on precision Higgs and top quark measurements. The so called "Higgs-strahlung" process ($e^+ e^- \to \mathrm{ZH}$) is a key for a model independent measurement of Higgs boson decays and extraction of its couplings. Precision top quark measurements will include the pair-production threshold scan, which is assumed to be the most precise method for the top-quark mass determination. The two subsequent energy stages will allow for extended Standard Model studies, including the direct measurement of the Higgs self-coupling and the top Yukawa coupling, but their main goals will be to search for signatures of Beyond the Standard Model phenomena. Presented in this contribution is a selection of recent results showing sensitivity of CLIC experiment to diverse BSM physics scenarios. Compared with hadron colliders, the low background conditions at CLIC provide extended discovery potential, in particular for the production through electroweak and/or Higgs boson interactions. This includes scenarios with extended scalar sectors, also motivated by dark matter, which can be searched for using associated production processes or cascade decays involving electroweak gauge bosons. In a wide range of models, new particles can be discovered almost up to the kinematic limit while the indirect search sensitivity extends up to ${\cal{O}}(100)$ TeV scales.
description: 6 pages, 4 figures. Presented on behalf of the CLICdp Collaboration at the European Physical Society Conference on High Energy Physics 2021 (EPS-HEP2021), 26-30 July 2021. Submission to Proceedings of Science (PoS)
Rewilding som planmål i Antropocæn
Creators: name: Ejrnæs, Rasmus
name: Bladt, Jesper
name: Fløjgaard, Camilla
Publisher: name: Tidsskrift for Kortlægning og Arealforvaltning
Year: 2017

description: Der er langt fra det moderne kulturlandskab med monotone marker og netværk af bebyggelser med veje og jernbaner til det vildnis, som var biodiversitetens vugge. De arter, der udgør biodiversiteten i dag, opstod i de forhistoriske økosystemer, hvor floderne gik over bredderne, stormfald og brande raserede skove og krat, og elefanter, næsehorn, heste, urokser og andre store dyr trampede og gnavede sig gennem økosystemerne. Det er netop menneskets tæmning af vildnisset, som er årsagen til biodiversitetskrisen. Det traditionelle svar på biodiversitetskrisen har været, at naturen er syg og truet og derfor har brug for vores pleje og omsorg. Denne forvaltningsmodel udfordres i dag af rewilding, som i stedet foreslår, at vi bygger på naturens evne til selvforvaltning, og i særdeleshed de store dyrs vigtige funktioner i økosystemerne. Uanset om målet er traditionel naturpleje eller rewilding, så lider biodiversiteten under pladsmangel, så der er brug for en rumlig planlægning, hvor naturen indgår som planmål. Rewilding kræver desuden store sammenhængende områder, og dem får vi kun, hvis der er politisk vilje til det.
description: Tidsskrift for Kortlægning og Arealforvaltning, Vol 123 No 48 (2017)
Discovery and characterization of magnetism in sigma-phase intermetallic Fe-Re compounds
Creators: name: Cieslak, J.
name: Dubiel, S. M.
name: Reissner, M.
name: Tobola, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Systematic experimental (vibrating sample magnetometry) and theoretical (electronic structure calculations using charge and spin self-consistent Korringa-Kohn-Rostoker Green function method) studies were performed on a series of intermetallic sigma-phase Fe(100-x)Re(x) (x = 43-53) compounds. Clear evidence was found that all investigated samples exhibit magnetism with an ordering temperature ranging between 65 K for x = 43 and 23 K for x = 53. The magnetism was revealed to be itinerant and identified as a spin-glass (SG) possibly having a re-entrant character. The SG was found to be heterogeneous viz. two regimes could be distinguished as far as irreversibility in temperature dependence of magnetization is concerned: (1) of a weak irreversibility and (2) of a strong one. According to the theoretical calculations the main contribution to the magnetism comes from Fe atoms occupying all five sub lattices. Re atoms have rather small moments. However, the calculated average magnetic moments are highly (ferromagnetic ordering model) or moderately (antiparallel ordering model) overestimated relative to the experimental data.
description: 15 pages, 15 figures, 1 table
Estrogen regulates Hippo signaling via GPER in breast cancer
Creators: name: Feng, Xu
name: Wang, Shuyang
name: Lv, Xian-Bo
name: Zhou, Xin
name: Zhu, Hongguang
name: Lei, Qun-Ying
name: Wang, Zhen
name: Li, Fulong
name: Sun, Yiping
name: Yuan, Haixin
name: Xiong, Yue
name: Guan, Kun-Liang
name: Yu, Fa-Xing
name: Liu, Peng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The G protein–coupled estrogen receptor (GPER) mediates both the genomic and nongenomic effects of estrogen and has been implicated in breast cancer development. Here, we compared GPER expression in cancerous tissue and adjacent normal tissue in patients with invasive ductal carcinoma (IDC) of the breast and determined that GPER is highly upregulated in cancerous cells. Additionally, our studies revealed that GPER stimulation activates yes-associated protein 1 (YAP) and transcriptional coactivator with a PDZ-binding domain (TAZ), 2 homologous transcription coactivators and key effectors of the Hippo tumor suppressor pathway, via the Gαq-11, PLCβ/PKC, and Rho/ROCK signaling pathways. TAZ was required for GPER-induced gene transcription, breast cancer cell proliferation and migration, and tumor growth. Moreover, TAZ expression positively correlated with GPER expression in human IDC specimens. Together, our results suggest that the Hippo/YAP/TAZ pathway is a key downstream signaling branch of GPER and plays a critical role in breast tumorigenesis.
Design of SPT-SLIM focal plane; a spectroscopic imaging array for the South Pole Telescope
Creators: name: Barry, P. S.
name: Anderson, A.
name: Benson, B.
name: Carlstrom, J. E.
name: Cecil, T.
name: Chang, C.
name: Dobbs, M.
name: Hollister, M.
name: Karkare, K. S.
name: Keating, G. K.
name: Marrone, D.
name: McMahon, J.
name: Montgomery, J.
name: Pan, Z.
name: Robson, G.
name: Rouble, M.
name: Shirokoff, E.
name: Smecher, G.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: The Summertime Line Intensity Mapper (SLIM) is a mm-wave line-intensity mapping (mm-LIM) experiment for the South Pole Telescope (SPT). The goal of SPT-SLIM is to serve as a technical and scientific pathfinder for the demonstration of the suitability and in-field performance of multi-pixel superconducting filterbank spectrometers for future mm-LIM experiments. Scheduled to deploy in the 2023-24 austral summer, the SPT-SLIM focal plane will include 18 dual-polarization pixels, each coupled to an $R = λ/Δλ$ = 300 thin- film microstrip filterbank spectrometer that spans the 2 mm atmospheric window (120-180 GHz). Each individual spectral channel feeds a microstrip-coupled lumped-element kinetic inductance detector, which provides the highly multiplexed readout for the 10k detectors needed for SPT-SLIM. Here we present an overview of the preliminary design of key aspects of the SPT-SLIM the focal plane array, a description of the detector architecture and predicted performance, and initial test results that will be used to inform the final design of the SPT- SLIM spectrometer array.
description: Submitted to special issue of JLTP (proceedings of LTD19)
Landadministrationssystemer i et menneskeretligt perspektiv
Creators: name: Enemark, Stig
Publisher: name: Tidsskrift for Kortlægning og Arealforvaltning
Year: 2017

description: Landadministrationssystemer er et redskab til at håndtere rettigheder, restriktioner og forpligtigelser i relation til jord og fast ejendom. Hver af disse tre komponenter har en menneskeretlig dimension, som relaterer sig til nationale politikker for styring af fast ejendoms anvendelse. Artiklen analyserer landadministrationssystemer i et sådant menneskeretligt perspektiv – med særlig fokus på udviklingslande.
description: Tidsskrift for Kortlægning og Arealforvaltning, Vol 123 No 48 (2017)
Magnetised neutron star crust within effective relativistic mean-field model
Creators: name: Parmar, Vishal
name: Das, H. C.
name: Sharma, M. K.
name: Patra, S. K.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Even though the crystallize nature of the neutron star crust plays a pivotal role in describing various fascinating astrophysical observations, its microscopic structure is not fully understood in the presence of a colossal magnetic field. In the present work, we study the crustal properties of a neutron star within an effective relativistic mean field framework in the presence of magnetic field strength $\sim 10^{17}$G. We calculate the equilibrium composition of the outer crust by minimizing the Gibbs free energy using the most recent atomic mass evaluations. The magnetic field significantly affects the equation of state (EoS) and the properties of the outer crust, such as neutron drip density, pressure, and melting temperature. For the inner crust, we use the compressible liquid drop model for the first time to study the crustal properties in a magnetic environment. The inner crust properties, such as mass and charge number distribution, isospin asymmetry, cluster density, etc., show typical quantum oscillations (De Haas-van Alphen effect) sensitive to the magnetic field's strength. The density-dependent symmetry energy influences the magnetic inner crust like the field-free case. We study the probable modifications in the pasta structures and it is observed that their mass and thickness changes by $\sim 10-15 \%$ depending upon the magnetic field strength. The fundamental torsional oscillation mode frequency is investigated for the magnetized crust in the context of quasiperiodic oscillations (QPO) in soft gamma repeaters. The magnetic field strengths considered in this work influences only the EoS of outer and shallow regions of the inner crust, which results in no significant change in global neutron star properties. However, the outer crust mass and its moment of inertia increase considerably with increase in magnetic field strength.
description: 18 pages, 13 figures, 5 tables, Published in Phys. Rev. D
The disk around the brown dwarf KPNO Tau 3
Creators: name: Broekhoven-Fiene, Hannah
name: Matthews, Brenda
name: Duchene, Gaspard
name: Di Francesco, James
name: Scholz, Aleks
name: Chrysostomou, Antonio
name: Jayawardhana, Ray
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present submillimeter observations of the young brown dwarfs KPNO Tau 1, KPNO Tau 3, and KPNO Tau 6 at 450 micron and 850 micron taken with the Submillimeter Common-User Bolometer Array on the James Clerke Maxwell Telescope. KPNO Tau 3 and KPNO Tau 6 have been previously identified as Class II objects hosting accretion disks, whereas KPNO Tau 1 has been identified as a Class III object and shows no evidence of circumsubstellar material. Our 3 sigma detection of cold dust around KPNO Tau 3 implies a total disk mass of (4.0 +/- 1.1) x 10^{-4} Msolar (assuming a gas to dust ratio of 100:1). We place tight constraints on any disks around KPNO Tau 1 or KPNO Tau 6 of <2.1 x 10^{-4} Msolar and <2.7 x 10^{-4} Msolar, respectively. Modeling the spectral energy distribution of KPNO Tau 3 and its disk suggests the disk properties (geometry, dust mass, and grain size distribution) are consistent with observations of other brown dwarf disks and low-mass T-Tauri stars. In particular, the disk-to-host mass ratio for KPNO Tau 3 is congruent with the scenario that at least some brown dwarfs form via the same mechanism as low-mass stars.
description: 18 pages (preprint format), 3 figures, published in ApJ
Identitets-, Byggelinie- og Servitutattest
Creators: name: Mouritsen, Anne Kristine Munk
name: Høyer, Søren Bitch
name: Jensen, Tina Møller
name: Laursen, Morten Blickfeldt
Publisher: name: Tidsskrift for Kortlægning og Arealforvaltning
Year: 2017

description: En Identitet-, Byggelinie- og Servitutattest er en attest, som anvendes til at atteste-re for et byggeris lovlige placering. Attesten knytter sig til et behov og der gives ingen retningslinjer i nogen lov, der præciserer, hvordan attesten skal udarbejdes. Attesten har i praksis opnået en grad af udbredelse, der gør, at det synes væsentligt at undersøge, hvorledes attestens anvendelse og indhold forholder sig til lan-dinspektørens professionelle ansvar. Derfor valgte en specialegruppe på Aalborg Universitet i foråret 2017 at undersøge emnet og denne artikel er blevet til i et efterfølgende samarbejde mel-lem specialegruppen og Aalborg Universitet med henblik på at formidle resultaterne. Undersøgelsen blev bygget op omkring den juridiske metode, hvilket afspejles i artiklen, der på denne ene side undersøger praksis og på den anden side reglen.
description: Tidsskrift for Kortlægning og Arealforvaltning, Vol 123 No 48 (2017)
Room-temperature on-chip generation of heralded single photons with switchable orbital angular momentum
Creators: name: Zhang, Shan
name: Feng, Xue
name: Zhang, Wei
name: Cui, Kaiyu
name: Liu, Fang
name: Huang, Yidong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In quantum optics, orbital angular momentum (OAM) is very promising to achieve high-dimensional quantum states due to the nature of infinite and discrete eigenvalue, which is quantized by the topological charge of l. Here, a heralded single-photon source with switchable OAM modes is proposed and demonstrated on silicon chip. At room-temperature, the heralded single photons with 11 OAM modes (l=2~6, -6~-1) have been successfully generated and switched through thermo-optical effect. We believe that such an integrated quantum source with multiple OAM modes and operating at room-temperature would provide a practical platform for high-dimensional quantum information processing. Moreover, our proposed architecture can also be extended to other material systems to further improve the performance of OAM quantum source.
Coronal Abundances in an Active Region: Evolution and Underlying Chromospheric and Transition Region Properties
Creators: name: Testa, Paola
name: Martinez-Sykora, Juan
name: De Pontieu, Bart
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The element abundances in the solar corona and solar wind are often different from those of the solar photosphere, typically with a relative enrichment of elements with low first ionization potential (FIP effect). Here we study the spatial distribution and temporal evolution of the coronal chemical composition in an active region (AR) over about 10 days, using Hinode/EIS spectra, and we also analyze coordinated IRIS observations of the chromospheric and transition region emission to investigate any evidence of the footprints of the FIP effect in the lower atmosphere. To derive the coronal abundances we use a spectral inversion method recently developed for the MUSE investigation (Cheung et al. 2019, De Pontieu et al. 2020). We find that in the studied active region (AR 12738) the coronal FIP bias presents significant spatial variations, with its highest values (~ 2.5-3.5) in the outflow regions at the boundary of the AR, but typically modest temporal variability. Some moss regions and some regions around the AR sunspot show enhanced FIP (~ 2-2.5) with respect to the AR core, which has only a small FIP bias of ~1.5. The FIP bias appears most variable in some of these moss regions. The IRIS observations reveal that the chromospheric turbulence, as derived from IRIS2 inversions of the Mg II spectra, is enhanced in the outflow regions characterized by the high FIP bias, providing significant new constraints to both models aimed at explaining the formation of AR outflows and models of chemical fractionation.
description: Submitted to the Astrophysical Journal. 14 pages, 7 figures
Human pDCs preferentially sense enveloped hepatitis A virions
Creators: name: McKnight, Kevin L.
name: Li, You
name: Hensley, Lucinda
name: Lemon, Stanley M.
name: Walker, Christopher M.
name: Lanford, Robert E.
name: Feng, Zongdi
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Unlike other picornaviruses, hepatitis A virus (HAV) is cloaked in host membranes when released from cells, providing protection from neutralizing antibodies and facilitating spread in the liver. Acute HAV infection is typified by minimal type I IFN responses; therefore, we questioned whether plasmacytoid dendritic cells (pDCs), which produce IFN when activated, are capable of sensing enveloped virions (eHAV). Although concentrated nonenveloped virus failed to activate freshly isolated human pDCs, these cells produced substantial amounts of IFN-α via TLR7 signaling when cocultured with infected cells. pDCs required either close contact with infected cells or exposure to concentrated culture supernatants for IFN-α production. In isopycnic and rate-zonal gradients, pDC-activating material cosedimented with eHAV but not membrane-bound acetylcholinesterase, suggesting that eHAV, and not viral RNA exosomes, is responsible for IFN-α induction. pDC activation did not require virus replication and was associated with efficient eHAV uptake, which was facilitated by phosphatidylserine receptors on pDCs. In chimpanzees, pDCs were transiently recruited to the liver early in infection, during or shortly before maximal intrahepatic IFN-stimulated gene expression, but disappeared prior to inflammation onset. Our data reveal that, while membrane envelopment protects HAV against neutralizing antibody, it also facilitates an early but limited detection of HAV infection by pDCs.
New results on the modification of jet structure in Heavy Ion collisions
Creators: name: Santos, Helena
Publisher: name: arXiv
Year: 2021
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: These proceedings report recent studies performed by the ALICE, ATLAS and CMS experiments on jet substructure in pp and Pb+Pb collisions at 5.02 TeV. The dependence of the modification of the jet shape on the dijet transverse moment um asymmetry is presented. Measurements of particles recoiling against the Z boson without being constrained to jet cone delimitations are shown. Fully-corrected measurements of the N-subjettiness within anti-kt R = 0.4 charged-particle jets are also described.
description: 5 pages, 3 figures, proceedings for LHCP2021
Quantum and classical separability of spin-orbit laser modes
Creators: name: Pereira, L. J.
name: Khoury, A. Z.
name: Dechoum, K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work we investigate the quantum noise properties of polarization vortices in connection with an intensity based Clauser-Horne-Shimony-Holt inequality for their spin-orbit separability. We evaluate the inequality for different input quantum states and the corresponding intensity fluctuations. The roles played by coherence and photon number squeezing provide a suitable framework for characterizing pure state spin-orbit entanglement. Structural inseparability of the spin-orbit mode requires coherence, an issue concerning either classical or quantum descriptions. In both cases, it can be witnessed by violation of this intensity based CHSH inequality. However, in the quantum domain, entanglement requires both coherence and reduced photon number fluctuations.
description: 7 pages, 3 figures
LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment
Creators: name: Brekken, Rolf A.
name: Nakada, Yuji
name: Amelio, Antonio L.
name: Wong, Kwok-Kin
name: Lea, Jayanthi S.
name: Peña, Christopher G.
name: Aloisio, Gina M.
name: Saatcioglu, Hatice D.
name: Zhang, Song
name: Castrillon, Diego H.
name: Cuevas, Ileana
name: DeBerardinis, Ralph J.
name: Miller, David S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Endometrial cancer is the most common gynecologic malignancy and the fourth most common malignancy in women. For most patients in whom the disease is confined to the uterus, treatment results in successful remission; however, there are no curative treatments for tumors that have progressed beyond the uterus. The serine/threonine kinase LKB1 has been identified as a potent suppressor of uterine cancer, but the biological modes of action of LKB1 in this context remain incompletely understood. Here, we have shown that LKB1 suppresses tumor progression by altering gene expression in the tumor microenvironment. We determined that LKB1 inactivation results in abnormal, cell-autonomous production of the inflammatory cytokine chemokine (C-C motif) ligand 2 (CCL2) within tumors, which leads to increased recruitment of macrophages with prominent tumor-promoting activities. Inactivation of Ccl2 in an Lkb1-driven mouse model of endometrial cancer slowed tumor progression and increased survival. In human primary endometrial cancers, loss of LKB1 protein was strongly associated with increased CCL2 expression by tumor cells as well as increased macrophage density in the tumor microenvironment. These data demonstrate that CCL2 is a potent effector of LKB1 loss in endometrial cancer, creating potential avenues for therapeutic opportunities.
The complete worldsheet S matrix of superstrings on AdS_3 x S^3 x T^4 with mixed three-form flux
Creators: name: Lloyd, Thomas
name: Sax, Olof Ohlsson
name: Sfondrini, Alessandro
name: Stefanski, Bogdan
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We determine the off-shell symmetry algebra and representations of Type IIB superstring theory on $AdS_3\times S^3 \times T^4$ with mixed R-R and NS-NS three-form flux. We use these to derive the non-perturbative worldsheet S matrix of fundamental excitations of the superstring theory. Our analysis includes both massive and massless modes and shows how turning on mixed three-form flux results in an integrable deformation of the S matrix of the pure R-R theory.
description: 48 pages, 2 figures
A Zoo of Deformed Jackiw-Teitelboim Models near Large Dimensional Black Holes
Creators: name: Sybesma, Watse
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider a charged Lifshitz black hole in the large transverse dimension limit. In this setup, the dynamics near the black hole horizon are shown to be effectively governed by a family of two-dimensional models of dilaton gravity depending on the ratio of the dynamical parameter characterizing the black hole and the dimension of spacetime. This family includes the Callan-Giddings-Harvey-Strominger (CGHS) and Jackiw-Teitelboim (JT) models and their charged equivalents. This family also contains classes of asymptotically anti-de Sitter models beyond JT, characterized by a running Ricci scalar, with the option of adding charge. Finally, we argue that specific non-minimally coupled probe scalars in the parent Lifshitz model become minimally coupled scalars in the two-dimensional theory, which is relevant for understanding semi-classical corrections in such models.
description: v2: Implemented changed of published version. v1: 12 pages, 1 figure, 1 table and one page of appendices
The mid-infrared appearance of the Galactic Mini-Starburst W49A
Creators: name: Stock, D. J.
name: Peeters, E.
name: Choi, W. D. -Y.
name: Shannon, M. J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The massive star forming region W49A represents one of the largest complexes of massive star formation present in the Milky Way and contains at least fifty young massive stars still enshrouded in their natal molecular cloud. We employ Spitzer/IRS spectral mapping observations of the northern part of W49A to investigate the mid-infrared (MIR) spatial appearance of the polycyclic aromatic hydrocarbon (PAH) bands, PAH plateau features, atomic lines and continuum emission. We examine the spatial variations of the MIR emission components in slices through two of the ultra compact-HII (UC-HII) regions. We find that the PAH bands reproduce known trends, with the caveat that the 6.2 $μ$m PAH band seems to decouple from the other ionized PAH bands in some of the UC-HII regions -- an effect previously observed only in one other object: the giant star forming region N66 in the LMC. Furthermore, we compare the nature of the emission surrounding W49A to that of `diffuse' sightlines. It is found that the surrounding emission can be explained by line of sight emission, and does not represent true `diffuse' material. Additionally, we examine the MIR appearance of star formation on various scales from UC-HII regions to starburst galaxies, including a discussion of the fraction of PAH emission in the 8 $μ$m IRAC filter. We find that the MIR appearance of W49A is that of a starburst on large scales yet its individual components are consistent with other galactic HII regions.
description: 23 pages, 14 figures, ApJ accepted
LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis
Creators: name: Kenney, Shannon C.
name: Ma, Shi-Dong
name: Ranheim, Erik A.
name: Jensen, Jeffrey L.
name: Cesarman, Ethel
name: Gumperz, Jenny E.
name: Plowshay, Julie
name: Asimakopoulos, Fotis
name: Xu, Xuequn
name: Burlingham, William J.
name: Tang, Weihua
name: Gulley, Margaret L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Epstein-Barr virus (EBV) infection transforms B cells in vitro and is associated with human B cell lymphomas. The major EBV oncoprotein, latent membrane protein 1 (LMP1), mimics constitutively active CD40 and is essential for outgrowth of EBV-transformed B cells in vitro; however, EBV-positive diffuse large B cell lymphomas and Burkitt lymphomas often express little or no LMP1. Thus, EBV may contribute to the development and maintenance of human lymphomas even in the absence of LMP1. Here, we found that i.p. injection of human cord blood mononuclear cells infected with a LMP1-deficient EBV into immunodeficient mice induces B cell lymphomas. In this model, lymphoma development required the presence of CD4+ T cells in cord blood and was inhibited by CD40-blocking Abs. In contrast, LMP1-deficient EBV established persistent latency but did not induce lymphomas when directly injected into mice engrafted with human fetal CD34+ cells and human thymus. WT EBV induced lymphomas in both mouse models and did not require coinjected T cells in the cord blood model. Together, these results demonstrate that LMP1 is not essential for EBV-induced lymphomas in vivo and suggest that T cells supply signals that substitute for LMP1 in EBV-positive B cell lymphomagenesis.