cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bioprocess development for the cell-based treatment of diabetes
Creators: name: Hoesli, Corinne
Publisher: name: University of British Columbia
Year: 2012

description: The widespread cellular treatment of type 1 diabetes by islet transplantation is limited by tissue shortage and graft rejection. This work describes two novel bioprocesses to immobilize pancreatic cells in alginate using: (1) hollow fiber bioreactors or (2) alginate bead generation by an adapted emulsion and internal gelation process. After optimization, live cell recovery rates and growth rates were not significantly different between these more scalable processes and conventional methods of alginate immobilization. After 10 days of alginate-immobilized culture, the insulin content of neonatal porcine cells cultured in a hollow fiber bioreactor increased by 4 fold, while the insulin expression of human isletdepleted tissue cultured in emulsion beads increased by 67 ± 32 fold, matching previous reports that used small-scale cultures. Solutions with >100 Pa·s viscosity could be used with the emulsion process to generate beads with higher concentration and greater antibody exclusion than has been so far permitted by nozzle-based encapsulators. The 5% alginate beads generated by the emulsion process led to blood glucose normalization of allogeneic β- cells transplanted into diabetic mice within 2 weeks, while mice transplanted with 1.5% alginate beads generated by a conventional encapsulator remained hyperglycemic after 20 days. The improved result with the 5% alginate emulsion beads was associated with lower graft-specific antibody plasma levels. These results suggest that the 5% alginate beads provided improved immune isolation of the graft. If human pancreatic progenitors are to be used for the large-scale generation of insulin+ cells in alginate, their expansion in serum-free medium will be a prerequisite. Pancreatic duct-like cells are expected to have more potential to generate insulin+ cells than the fibroblast-like cells that overgrow unsorted cultures of islet-depleted human pancreatic tissue. The last part of this thesis describes the magneticactivated depletion of CD90-expressing cells, which reduced the fraction of CD90+ fibroblast-like cells from 34 ± 20% to 1.3 ± 0.6%. This allowed the expansion of the duct-like cell population in an optimized serum-free medium. These novel pancreatic cell culture methods could be used to generate and/or offer immune protection to insulin+ cells for the clinical-scale cellular treatment of diabetes.
Monster black holes
Creators: name: Cappellari, Michele
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A combination of ground-based and spacecraft observations has uncovered two black holes of 10 billion solar masses in the nearby Universe. The finding sheds light on how these cosmic monsters co-evolve with galaxies.
description: 2 pages, 1 figure, LaTeX. Published in Nature "News & Views"
Age-Specific Effects of Visual Feature Binding
Creators: name: Werrmann, Michelle
name: Niedeggen, Michael
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: feature binding
subject: visual working memory
subject: aging
subject: ERP
subject: 100 Philosophie und Psychologie::150 Psychologie::150 Psychologie

description: Temporary binding of visual features enables objects to be stored and maintained in the visual working memory as a singular structure, irrespective of its inherent complexity. Although working memory capacity is reduced in aging, previous behavioral studies suggest that binding is preserved. Using event-related brain potentials (ERPs), we tested whether stimulus encoding is different in younger (N = 26, mean age = 28.5) and older (N = 22; mean age = 67.4) participants in a change detection task. The processing costs of binding were defined by the difference between feature-alone (color or shape) and feature-binding (color–shape) conditions. The behavioral data revealed that discrimination ability was reduced in the feature-binding condition, and that this effect was more attenuated in older participants. A corresponding ERP effect was not found in early components related to visual feature detection and processing (posterior N1 and frontal P2). However, the late positive complex (LPC) was more often expressed in the feature-binding condition, and the increase in amplitude was more pronounced in older participants. The LPC can be related to attentional allocation processes which might support the maintenance of the more complex stimulus representation in the binding task. However, the selective neural overactivation in the encoding phase observed in older participants does not prevent swap errors in the subsequent retrieval phase.
Medsip: Digital Mammographic Image Database For Medicine And Machine Learning Research
Creators: name: Harris V Georgiou (MSc, PhD)
name: Michael E Mavroforakis (MSc, PhD)
Publisher: name: Zenodo
Year: 2016
Subjects: x-ray
mammography
medical imaging
image analysis
machine learning

description: Technical presentation (final).

Latsis Foundation – Symposium for the presentation of funded research works for 2010 (5-May-2011).
description: For details see:
MedSIP: Original Annotated Database of High-Quality Digital Mammographic Images Publicly Available to the Research Community (summary in Greek)
Ν. Dimitropoulos, H. Georgiou, Μ. Mavroforakis, P. Bouboulis, H. Mavroforakis
37th Annual Greek Medical Conference 2011 (EPIS-37), 17-21 May 2011 @ Athens, Greece.
C-2 Basic Master Plan Map (1959)
Creators: name: Pan American World Airways Inc.
Year: 1959
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: Master Plan Basic Layout (1959).
Is the Neuropeptide PEN a Ligand of GPR83?
Creators: name: Giesecke, Yvonne
name: Asimi, Vahid
name: Stulberg, Valentina
name: Kleinau, Gunnar
name: Scheerer, Patrick
name: Koksch, Beate
name: Grötzinger, Carsten
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: GPR83
subject: PEN
subject: proSAAS
subject: orphan receptor
subject: GPCR
subject: peptide
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: G protein-coupled receptor 83 (GPR83) is a class A G protein-coupled receptor with predominant expression in the cerebellum and proposed function in the regulation of food intake and in anxiety-like behavior. The neuropeptide PEN has been suggested as a specific GPR83 ligand. However, conflicting reports exist about whether PEN is indeed able to bind and activate GPR83. This study was initiated to evaluate PEN as a potential ligand of GPR83. Employing several second messenger and other GPCR activation assays as well as a radioligand binding assay, and using multiple GPR83 plasmids and PEN peptides from different sources, no experimental evidence was found to support a role of PEN as a GPR83 ligand.
title: Investigating the role of RNA modifying enzymes in RNA virus infection
Creators: name: Jarmson, Innes Gordon
Publisher: name: University of Glasgow
Year: 2025

description: Viruses, as obligate intracellular parasites, rely heavily on their close interactions with host cells to replicate. To have a successful lifecycle, a virus must subvert the host machinery for its own use, while avoiding inducing an immune response in the cell. One mechanism of inducing an immune response is the sensing of foreign nucleic acid, whether that be through unusual nucleic acid structure or specific motifs on viral RNA and DNA. In the resting cell, all post transcriptional modifications of cellular RNA play an important role in the life cycle of RNA, and these modifications in turn act as a signal in the cell to avoid triggering an immune response. In the eternal battle of viruses and their hosts to adapt and counter adapt to overcome each other, viruses have evolved intricate mechanisms to avoid mounting an immune response. One such method is to mimic the cellular landscape of RNA to avoid being sensed by the host. To do this, viruses hijack cellular RNA modifying enzymes to ‘decorate’ their genomes. These modifications also serve a functional purpose in viral RNA and can enhance processes like translation of viral mRNAs. However, in the co-evolution of virus and host trying to counter each other, the host cell can also methylate viral RNA to initiate an innate immune mechanism to restrict viral growth. To understand the dynamicity of RNA modifications in viral infection, I have created a CRISPR-Cas9 knockout platform where I systematically knockout each known human RNA modifying enzyme and observe if the lack of the gene increases or decreases viral infection. This allows us to determine whether the gene of interest inhibits or enhances viral infection. Those genes that are identified as necessary for viral infection are subjected to further analysis to identify the function of these RNA modifications and if the same modifications are shared between viruses. Using this platform, I identified several RNA modifying enzymes and characterised one protein that had an antiviral effect against several viruses – NOP2. In the resting cell NOP2 is involved in ribosome biogenesis and I established that after infection it switches its activity to become an antiviral effector. The data in this thesis demonstrates the utility of arrayed CRISPR/Cas9 screening to identify new proteins involved in virus infection and how it can be used as a discovery-based platform to further characterise the host-virus arms race.
Cape Canaveral Air Force Station (CCAFS) Basic Information Guide: Cape Canaveral Spaceport Facilities, 2002
Creators: name: Space Gateway Support (SGS) Master Planning
Publisher: name: Space Gateway Support (SGS) Master Planning
Year: 2002
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs

description: 2002 Basic Information Guide for Cape Canaveral Spaceport Facilities at both CCAFS and KSC.
Crustal failure during binary inspiral
Creators: name: Penner, A. J.
name: Andersson, N.
name: Jones, D. I.
name: Samuelsson, L
name: Hawke, I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present the first fully relativistic calculations of the crustal strain induced in a neutron star by a binary companion at the late stages of inspiral, employing realistic equations of state for the fluid core and the solid crust. We show that while the deep crust is likely to fail only shortly before coalescence, there is a large variation in elastic strain, with the outermost layers failing relatively early on in the inspiral. We discuss the significance of the results for both electromagnetic and gravitational-wave astronomy.
description: 5 pages, 3 eps figures
Air Force Eastern Test Range, Basic Information Guide, 1973
Creators: name: Pan American World Airways Inc.
Year: 1973
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Remote Sensing
valueUri: https://core.tdar.org/browse/investigation-type/22/remote-sensing
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: 1973 Basic Information Guide for the Air Force Eastern Test Range at Cape Kennedy Air Force Station (CKAFS).
Mechanismen des Chromatin-Remodellings am Beispiel der molekularen Smyd1-PML-SUMO1-Achse
Creators: name: Berkholz, Janine
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: Chromatin Remodeling
subject: Smyd1
subject: Endothelial cells
subject: PML
subject: Histone methylation
subject: nucleolus
subject: PML Nuclear Bodies
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Die vorliegende Arbeit hat das Ziel, das zellphysiologische Wirkungsspektrum der molekularen Smyd1-PML-SUMO1-Achse im Rahmen des Chromatin-Remodellings zu beschreiben, die in meiner Forschung u.a. mittels umfangreicher Transfektionsversuche mit Vektoren bzw. siRNA sowie ChIP-Analysen und biologischen Assays identifiziert wurden. Im Mittelpunkt der Darstellung steht dabei die molekulare Charakterisierung von drei Funktionsmodulen, an denen Smyd1 in kultivierten Myoblasten, Endothelzellen oder Glattmuskelzellen sowie in Gefäßabschnitten von Arteriosklerose- und Nicht-Arteriosklerose-Patienten beteiligt ist: 1. Smyd1 als Kofaktor der Transkription, 2. Smyd1 als Histonmethyltransferase (HMT) und 3. Smyd1 in Interaktion mit PML zur Organisation der SUMOylierungsfabriken PML-Kernkörperchen. Dabei wurde herausgefunden, dass 1. Smyd1 im Komplex mit dem Muskel-spezifischen Transkriptionsfaktor skNAC die Transkription ausgewählter Gene in differenzierten Myoblasten induziert, die zur Myofibrillogenese, zu Entzündungsvorgängen und zum Zellstoffwechsel beitragen. 2. Smyd1 in humanen Endothelzellen nach Exposition mit Lipopolysacchariden (LPS) die Produktion und Sekretion von IL-6 erhöht. Die Umsetzung erfolgt entweder über Trimethylierung des Lysin 4 des Histons 3 im Bereich des IL-6 Promotors als auch indirekt über die Aktivierung des Transkriptionsfaktors NF-kB. 3. Smyd1 die eigene Konzentration in Endothelzellen durch einen negativen Feedbackmechanismus mit negativer Rückkopplung beeinflusst. Dieser Mechanismus umfasst die Induktion der PML-Expression auf mRNA- und Proteinebene, den Transport des PML in den Nucleus und den vermehrten Zusammenbau von PML-NBs, wodurch zunächst PML und dann Smyd1 SUMOyliert werden. Hierdurch wiederum wird Smyd1 für den Transport ins Zytoplasma und den abschließenden proteosomalen Abbau markiert. Dass die SUMOylierung nicht nur ein Degradationssignal ist, sondern auch funktionell relevant sein kann, wird in Koronargefäßen von Arteriosklerose-Patienten gezeigt, in denen SUMOyliertes PML zum Phänotypwechsel (‚Phenotypic Switch’) von glatten Muskelzellen beiträgt, so wie sie typisch für diese Zellen in arteriosklerotischen Plaques ist. Es wurden Faktoren identifiziert (IFN-gamma, TNF-alpha, LPS), die an unterschiedlichen Schnittstellen zur Regulation der Smyd1-Konzentration in der untersuchten Endothelzelllinie einwirken. Die experimentellen Daten belegen, dass Smyd1 ein multifunktionales Molekül ist, das an verschiedenen molekularen funktionellen Modulen beteiligt ist und dabei über SUMOylierung und HMT-Aktivität wirkt.
Vorschläge für eine situierte Forschungsperspektive auf Gewalt(freiheit) im Kontext sozialer Mobilisierung
Creators: name: Grimm, Jannis
name: Salehi, Mariam
name: Franzki, Hannah
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Protest
subject: Konflikt
subject: Gewalt
subject: Soziale Bewegungen
subject: 300 Social sciences::320 Political science::320 Political science

description: Welche Rolle spielen Disruption und Gewalt mit Blick auf den Erfolg von sozialer Mobilisierung und wie können sie legitimiert werden? Wo endet ziviler Ungehorsam und beginnt radikaler Protest? Potenzielle wissenschaftliche Antworten auf diese umstrittenen Fragen sind gebunden an ontologische, normative und epistemologische Vorannahmen, ebenso wie Versuche der definitorischen Grenzziehung zum Gewaltbegriff. Dies verdeutlicht der einleitende Beitrag anhand einer Rekonstruktion aktueller empirischer und theoretischer Forschungsdiskurse zum Nexus Gewalt(freiheit) und Widerstand. Statt zu versuchen eine objektive Bestimmung politischer Grenzbegriffe vorzunehmen werden Perspektiven für die Selbstverortung derer aufgeworfen, die gewaltförmige Phänomene in ihren sozialen, temporalen, relationalen und diskursiven Zusammenhängen zu beschreiben suchen. Der Beitrag plädiert für eine explizit situierte Forschung zu Gewalt(freiheit) im Kontext sozialer Mobilisierung.
description: How can disruption and violence condition protest success, and how can they be legitimized? Where does civil disobedience end and radical protest begin? Potential answers to these controversial questions, as well as attempts at defining the concept of violence, are tied to ontological, normative, and epistemological presuppositions that shape the positionality of those providing those answers. This introduction takes stock of recent empirical and theoretical debates on the (non)violence-resistance-nexus to argue that attempts at objectively determining essentially political concepts are futile if they remain decoupled from the empirical and normative contexts that produce them. Consequently, we highlight several ways how scholars investigating violent phenomena and their social, temporal, relational, and discursive embedding may position themselves vis-à-vis their object of study, in an attempt to move the fragmented debate on (non)violence in the context of social mobilization towards a more situated and differentiated discussion.
The Non-linear Optical Spin Hall Effect and Long-Range Spin Transport in Polariton Lasers
Creators: name: Kammann, Elena
name: Liew, Timothy C. H.
name: Ohadi, Hamid
name: Cilibrizzi, Pasquale
name: Tsotsis, Panayiotis
name: Hatzopoulos, Zacharias
name: Savvidis, Pavlos G.
name: Kavokin, Alexey V.
name: Lagoudakis, Pavlos G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We report on the experimental observation of the non-linear analogue of the optical spin Hall effect under highly non-resonant circularly polarized excitation of an exciton polariton condensate in a GaAs/AlGaAs microcavity. Initially circularly polarized polariton condensates propagate over macroscopic distances while the collective condensate spins coherently precess around an effective magnetic field in the sample plane performing up to four complete revolutions.
Cultural Resources Magnetometer Survey Brevard County, Canaveral Harbor, Florida
Creators: name: Oceanprobe, Inc
Year: 1988
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Magnetic Anomalies
valueUri: https://core.tdar.org/browse/other-keyword/5074/magnetic-anomalies
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: echosounder
valueUri: https://core.tdar.org/browse/other-keyword/167350/echosounder
subject: Magnetometer
valueUri: https://core.tdar.org/browse/other-keyword/1484/magnetometer
subject: Historic Background Research
valueUri: https://core.tdar.org/browse/investigation-type/18/historic-background-research
subject: Geophysical Survey
valueUri: https://core.tdar.org/browse/investigation-type/23/geophysical-survey
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: A cultural resources investigation was conducted to investigate a potential borrow area offshore Cape Canaveral in the Atlantic Ocean. Field work was conducted in February 1988, utilizing a proton precession magnetometer, precision echosounder and digitizer, microwave positioning system with three lines of position, computerized data acquisition and track guidance system, all deployed from a specialized nonmetallic shallow draft survey vessel. A total of 132 magnetic anomalies were detected during the survey, and one particular group of anomalies required the field crew to conduct a finer grid search for a higher degree of definition. Historical archival research from Colonial period to present was conducted utilizing a number of sources, including Florida State archives.
Cultural Resources Staff Visit Report, Eastern Space and Missile Center
Creators: name: Husted, Wilfred M.
Year: 1981
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: communication annexes
valueUri: https://core.tdar.org/browse/site-type/4526/communication-annexes
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management
subject: Research Design / Data Recovery Plan
valueUri: https://core.tdar.org/browse/investigation-type/9/research-design-data-recovery-plan

description: During July 13-15, 1981, there was a visit to Patrick Air Force Base (AFB), Cape Canaveral Air Force Station (AFS) and six nearby tracking and communications stations to obtain information to develop a plan and cost estimate for a cultural resource survey and evaluation of these eight facilities. After visiting Patrick AFB and the six ancillary stations, it became apparent that there was little probability of discovering significant cultural resources at any of these seven areas.
Gasification of bio-oil and bio-oil/char slurry
Creators: name: Sakaguchi, Masakazu
Publisher: name: University of British Columbia
Year: 2010

description: Economic utilization of biomass as a fuel has been limited by transportation cost. One suggested remedy to address the problems of processing biomass on a large scale is to pyrolyze solid biomass at numerous local sites and transport the resulting liquid or liquid/char slurry to a large centralized conversion plant. This research involves the gasification of biomass fast pyrolysis oil, so called bio-oil, and a slurry mixture of bio-oil and fast pyrolysis char into synthesis gas. Kinetics of the reaction of steam with chars was studied using a thermo-gravimetric analyzer. Slurry Char was produced by pyrolysis of an 80 wt% bio-oil/20 wt% char mixture at nominal heating rates of 100–10,000°C/s. The resulting Slurry Char was subjected to steam gasification with 10–50 mol% steam at 800–1200°C. Reactivity of the Slurry Chars increased with the pyrolysis heating rate, but was lower than that of Original Chars. Kinetic parameters were established for a power-law rate model. Some measurements were initially done of gasification in CO₂. A fluidized bed reactor, equipped with an atomization system, was constructed for gasification of bio-oil and slurry. The reactor contained either sand, or Ni-based catalyst. Experiments included gasification with pure steam and air. Effects of bed temperatures in the range 720–850°C, steam-to-carbon molar ratios of 2.0–7.5, and air ratios of 0–0.5 on gas composition and yields were tested. The carbon conversion of bio-oil to gas was found to be greater than that of slurry. The product gas composition was affected significantly by catalysis of the water-gas shift and the steam gasification. Greater yields of hydrogen and lesser yields of CO and hydrocarbons were found when catalyst was used. On a dry, inert-free basis, gases of up to 61% H₂ were obtained. The data were compared with a thermodynamic equilibrium model. The product gas yield was reasonably predictable by the model. A mass and energy balance model of steam gasification in a dual-bed gasifier-combustor revealed that energy requirements are sensitive to the steam/carbon ratio and to the recovery of latent heat in the produced gas.
Multi-Wavelength Modelling of the Beta Leo Debris Disc: 1, 2 or 3 planetesimal populations?
Creators: name: Churcher, L. J.
name: Wyatt, M. C.
name: Duchêne, G.
name: Sibthorpe, B.
name: Kennedy, G.
name: Matthews, B. C.
name: Kalas, P.
name: Greaves, J.
name: Su, K.
name: Rieke, G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: In this paper we present a model of the Beta Leo debris disc, with an emphasis on modelling the resolved PACS images obtained as part of the Herschel key programme DEBRIS. We also present new SPIRE images of the disc at 250 microns, as well as new constraints on the disc from SCUBA-2, mid-IR and scattered light imaging. Combining all available observational constraints, we find three possible models for the Beta Leo (HD102647) debris disc: (i) A 2 component model, comprised of a hot component at 2 AU and a cold component from 15-70 AU. (ii) A 3 component model with hot dust at 2 AU, warm dust at 9 AU, and a cold component from 30-70 AU, is equally valid since the cold emission is not resolved within 30 AU. (iii) A somewhat less likely possibility is that the system consists of a single very eccentric planetesimal population, with pericentres at 2 AU and apocentres at 65 AU. Thus, despite the wealth of observational constraints significant ambiguities remain; deep mid-IR and scattered light imaging of the dust distribution within 30 AU seems the most promising method to resolve the degeneracy. We discuss the implications for the possible planetary system architecture; e.g., the 2 component model suggests planets may exist at 2-15 AU, while the 3 component model suggests planets between 2-30 AU with a stable region containing the dust belt at 9 AU, and there should be no planets between 2-65 AU in the eccentric planetesimal model. We suggest that the hot dust may originate in the disintegration of comets scattered in from the cold disc, and examine all A stars known to harbour both hot and cold dust to consider the possibility that the ratio of hot and cold dust luminosities is indicative of the intervening planetary system architecture.
description: 20 pages, 14 figures. Accepted to MNRAS
Army Ballistic Missile Programs at Cape Canaveral 1953-1988
Creators: name: Cleary, Mark C.
Publisher: name: 45th Space Wing, USAF
Year: 2022
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: Jupiter
valueUri: https://core.tdar.org/browse/other-keyword/121/jupiter
subject: Juno II
valueUri: https://core.tdar.org/browse/other-keyword/167323/juno-ii
subject: Pershing
valueUri: https://core.tdar.org/browse/other-keyword/167324/pershing
subject: Redstone
valueUri: https://core.tdar.org/browse/other-keyword/167322/redstone

description: This study begins with a summary of the major events leading up to the REDSTONE missile program at Cape Canaveral. It includes an overview of RAF Bomber Command’s raid against Peenemünde in August 1943 and the U.S. Army’s recruitment of Wernher von Braun and his ‘hand-picked’ team of rocket experts in 1945. It continues with a sketch of the Army’s early missile projects at Fort Bliss, Texas, and the recommendations that shaped the REDSTONE missile.
Air Force Eastern Test Range, Basic Information Guide, 1979
Creators: name: Pan American World Airways Inc.
Year: 1979
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Remote Sensing
valueUri: https://core.tdar.org/browse/investigation-type/22/remote-sensing
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: 1979 Basic Information Guide for the Air Force Eastern Test Range at Cape Kennedy Air Force Station (CKAFS).
Therapeutic Effects of Oral Application of Menthol and Extracts from Tormentil (Potentilla erecta), Raspberry Leaves (Rubus idaeus), and Loosestrife (Lythrum salicaria) during Acute Murine Campylobacteriosis
Creators: name: Bandick, Rasmus
name: Busmann, Lia V.
name: Mousavi, Soraya
name: Shayya, Nizar W.
name: Piwowarski, Jakub P.
name: Granica, Sebastian
name: Melzig, Matthias F.
name: Bereswill, Stefan
name: Heimesaat, Markus M.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: tormentil (Potentilla erecta)
subject: raspberry leaves (Rubus idaeus)
subject: loosestrife (Lythrum salicaria)
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::615 Pharmakologie, Therapeutik

description: Human food-borne infections with the enteropathogen Campylobacter jejuni are becoming increasingly prevalent worldwide. Since antibiotics are usually not indicated in campylobacteriosis, alternative treatment regimens are important. We here investigated potential disease-alleviating effects of menthol and of extracts from tormentil, raspberry leaves, and loosestrife in acute murine campylobacteriosis. Therefore, C. jejuni-infected microbiota-depleted IL-10−/− mice were orally treated with the compounds alone or all in combination from day 2 until day 6 post-infection. Whereas neither treatment regimen affected gastrointestinal pathogen loads, the combination of compounds alleviated C. jejuni-induced diarrheal symptoms in diseased mice on day 6 post-infection. Furthermore, the therapeutic application of tormentil and menthol alone and the combination of the four compounds resulted in lower colonic T cell numbers in infected mice when compared to placebo counterparts. Notably, pro-inflammatory cytokines measured in mesenteric lymph nodes taken from C. jejuni-infected mice following tormentil, menthol, and combination treatment did not differ from basal concentrations. However, neither treatment regimen could dampen extra-intestinal immune responses, including systemic pro-inflammatory cytokine secretion on day 6 post-infection. In conclusion, the combination of menthol and of extracts from tormentil, raspberry leaves, and loosestrife constitutes an antibiotic-independent approach to alleviate campylobacteriosis symptoms.
The Global Turn in Nationalism: The USA as a Battleground for Hinduism and Hindu Nationalism
Creators: name: Kim, Sophie-Jung H.
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Hinduism
subject: Hindu nationalism
subject: 20th century
subject: migration
subject: deterritorialmovement
subject: counterpublic
subject: 200 Religion::200 Religion::200 Religion

description: Hindu nationalism operates on a global scale today. Evinced by the transnational networks of the Sangh Parivar and the replication of strategies such as amending textbooks and patriotic rewriting of history, politics and discourse of Hindu nationalism are not solely contained to the territorial boundary of the nation. In this globalized battle for and against Hindu nationalism, the United States of America serves as an important site. In light of this, this article puts together existing scholarship on diasporic Hindu nationalism with late nineteenth-and early twentieth-century deterritorial history of Indian nationalism to present a broader framework for historicizing Indian activism in the US. It argues that while long-distance Hindu nationalism in the US cannot be traced before the 1970s, examining the early experiences of Indian activists in the US offers useful insights with which to evaluate the ongoing battles of Hindu nationalism in the US and opens another field of enquiry: Hindutva’s counterpublic.
Cape Canaveral Air Force Station (CCAFS) Basic Information Guide: Eastern Test Range, 1991 Revision
Creators: name: Johnson Controls World Services Inc.
Year: 1991
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs

description: 1991 revised list of facilities at the Eastern Test Range of the Cape Canaveral Air Force Station.
Blueprint of Shopping Mall Parking Lot and Street View H Revised, October 18, 1939
Creators: name: Smythe, Richard Haviland
name: Melville, Ward, 1887-1977
name: Organization, Ward Melville Heritage
name: Stony Brook Community Fund
Publisher: name: Unknown
Year: 0
Subjects: Stony Brook
Sketches
Blueprints
Plans
Architects
Shopping centers
Architectural drawings
Stores & shops

description: This blueprint shows the revised plan for parking lot and street view "H" of a shopping center located in Stony Brook, L. I. This plan was completed by architect Richard Haviland Smythe, located at 681 fifth avenue, New York.
Conception and Use of Ontologies for Indexing and Searching by Semantic Contents of Video Courses
Creators: name: Merzougui, Ghalia
name: Djoudi, Mahieddine
name: Behaz, Amel
Publisher: name: arXiv
Year: 2012
Subjects: subject: Digital Libraries (cs.DL)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Nowadays, the video documents like educational courses available on the web increases significantly. However, the information retrieval systems today can not return to the users (students or teachers) of parts of those videos that meet their exact needs expressed by a query consisting of semantic information. In this paper, we present a model of pedagogical knowledge of current videos. This knowledge is used throughout the process of indexing and semantic search segments instructional videos. Our experimental results show that the proposed approach is promising.
description: 9 pages, 5 figures, 1 table and 2 codes
Magnetically driven superconductivity in CeCu2Si2
Creators: name: Stockert, O.
name: Arndt, J.
name: Faulhaber, E.
name: Geibel, C.
name: Jeevan, H. S.
name: Kirchner, S.
name: Loewenhaupt, M.
name: Schmalzl, K.
name: Schmidt, W.
name: Si, Q.
name: Steglich, F.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The origin of unconventional superconductivity, including high-temperature and heavy-fermion superconductivity, is still a matter of controversy. Spin excitations instead of phonons are thought to be responsible for the formation of Cooper pairs. Using inelastic neutron scattering, we present the first in-depth study of the magnetic excitation spectrum in momentum and energy space in the superconducting and the normal states of CeCu2Si2. A clear spin excitation gap is observed in the superconducting state. We determine a lowering of the magnetic exchange energy in the superconducting state, in an amount considerably larger than the superconducting condensation energy. Our findings identify the antiferromagnetic excitations as the major driving force for superconducting pairing in this prototypical heavy-fermion compound located near an antiferromagnetic quantum critical point.
description: 30 pages, including supplementary material
Florida Master Site File 8BR00084
Creators: name: J. Granberry
Year: 1953
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: 8BR00084
valueUri: https://core.tdar.org/browse/site-name/116451/8br00084
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station

description: Florida Master Site File for 8BR00084, a historic earthwork near Cape Canaveral Lighthouse and opposite Launch Pad 39B.
From Vector Meson Dominance to Quark-Hadron Duality
Creators: name: Bramon, Albert
Publisher: name: arXiv
Year: 2012
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A short review of the many contributions to hadron physics made by Mario Greco is presented. The review roughly covers his production between 1971 and 1974, just before the advent of QCD, when quark-model ideas, duality principles and vector meson dominance were widely accepted, developed and applied. The present author had the privilege to collaborate with Mario in most of these contributions and looking backward in time to remember the good old days we spent together in Frascati has been a great pleasure.
description: Talk in honour of Mario Greco presented at the Rencontres de la Vall\'ee d'Aoste 2011, La Thuile, Italy
HRD检测技术
Creators: name: 陈冬菊(Dongju Chen)
Publisher: name: CNGB
Year: 2021
Subjects: Genome sequencing
Multiisolate
Other
生物信息算法及应用

description: Background: The gain or loss of large chromosomal regions or even whole chromosomes is termed as genomic scarring and can be observed as copy number variations resulting from the failure of DNA damage repair. Results: In this study, a new algorithm called Genomic Scar Analysis (GSA) has developed and validated to calculate homologous recombination deficiency (HRD) score. The two critical submodules were tree recursion (TR) segmentation and filtering, and the estimation and correction of the tumor purity and ploidy. Then, this study evaluated the rationality of segmentation and genotype identification by the GSA algorithm and compared with other two algorithms, PureCN and ASCAT, found that the segmentation result of GSA algorithm was more logical. In addition, the results indicated that the GSA algorithm had an excellent predictive effect on tumor purity and ploidy, if the tumor purity was more than 20%. Furtherly, this study evaluated the HRD scores and BRCA1/2 deficiency status of 195 clinical samples, and the results indicated that the accuracy was 0.98 (comparing with Affymetrix OncoScan™ assay) and the sensitivity was 95.2% (comparing with BRCA1/2 deficiency status), both were well-behaved. Finally, HRD scores and 16 genes mutations (TP53 and 15 HRR pathway genes) were analyzed in 17 cell lines, the results showed that there was higher frequency in HRR pathway genes in high HRD score samples. Conclusions: This new algorithm, named as GSA, could effectively and accurately calculate the purity and ploidy of tumor samples through NGS data, and then reflect the degree of genomic instability and large-scale copy number variations of tumor samples.
Modeling quantum noise for efficient testing of fault-tolerant circuits
Creators: name: Magesan, Easwar
name: Puzzuoli, Daniel
name: Granade, Christopher E.
name: Cory, David G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Understanding fault-tolerant properties of quantum circuits is important for the design of large-scale quantum information processors. In particular, simulating properties of encoded circuits is a crucial tool for investigating the relationships between the noise model, encoding scheme, and threshold value. For general circuits and noise models, these simulations quickly become intractable in the size of the encoded circuit. We introduce methods for approximating a noise process by one which allows for efficient Monte Carlo simulation of properties of encoded circuits. The approximations are as close to the original process as possible without overestimating their ability to preserve quantum information, a key property for obtaining more honest estimates of threshold values. We numerically illustrate the method with various physically relevant noise models.
description: 6 pages, 1 figure
Cape Canaveral Air Force Station (CCAFS) Basic Information Guide: Eastern Test Range, 1983 Revision
Creators: name: Pan Am World Services, Inc.
Year: 1983
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs

description: 1983 revised list of facilities at the Eastern Test Range of the Cape Canaveral Air Force Station.
Air Force Eastern Test Range, Basic Information Guide, 1977
Creators: name: Pan American World Airways Inc.
Year: 1977
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: BIGS
valueUri: https://core.tdar.org/browse/other-keyword/164553/bigs
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Architectural Survey
valueUri: https://core.tdar.org/browse/investigation-type/2/architectural-survey
subject: Remote Sensing
valueUri: https://core.tdar.org/browse/investigation-type/22/remote-sensing
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: 1977 Basic Information Guide for the Air Force Eastern Test Range at Cape Kennedy Air Force Station (CKAFS).
Noether Gauge Symmetry Approach in f(R) Gravity
Creators: name: Hussain, Ibrar
name: Jamil, Mubasher
name: Mahomed, F. M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Physics (physics.gen-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We discuss the f(R) gravity model in which the origin of dark energy is identified as a modification of gravity. The Noether symmetry with gauge term is investigated for the f(R) cosmological model. By utilization of the Noether Gauge Symmetry (NGS) approach, we obtain two exact forms f(R) for which such symmetries exist. Further it is shown that these forms of f(R) are stable.
description: 6 pages, accepted by Astrophys. Sp. Sci
A Cultural Resources Magnetometer Survey of Canaveral Sand Bypass Borrow Site, Brevard County, Florida, Draft Copy
Creators: name: Mid-Atlantic Technology
Year: 1992
Subjects: subject: Florida (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2273/florida-state-territory
subject: Cape Canaveral
valueUri: https://core.tdar.org/browse/geographic-keyword/23155/cape-canaveral
subject: Brevard (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/14443/brevard-county
subject: Shipwreck
valueUri: https://core.tdar.org/browse/site-type/367/shipwreck
subject: Cape Canaveral Air Force Station
valueUri: https://core.tdar.org/browse/other-keyword/96049/cape-canaveral-air-force-station
subject: Magnetometer
valueUri: https://core.tdar.org/browse/other-keyword/1484/magnetometer
subject: Geophysical Survey
valueUri: https://core.tdar.org/browse/investigation-type/23/geophysical-survey

description: The U. S. Army Corps of Engineers, Jacksonville District is proposing a plan that will involve transferring 530,000 cubic yards of sand from the north side of Canaveral Barge Canal Inlet at Cape Canaveral, Florida and placing it on the beach south of the inlet over a distance of 11,885 feet. Because of the potential for historic shipwrecks in the proposed project area, the Jacksonville District through their open-ended planning contract with Gulf Engineers and Consultants, Inc., of Baton Rouge, Louisiana, enlisted Mid-Atlantic Technology of Wilmington, North Carolina to conduct a literature search and magnetometer survey to identify any submerged cultural resources in the proposed project area. This is a draft copy.