cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The interplay of actor-related strategies and political context: a fuzzy-set QCA analysis of structural reforms in continental welfare states
Creators: name: Stiller, Sabina
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Space Science
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: European welfare states face numerous challenges which often necessitate risky policy choices. This article focuses on the role of key political actors, asking which actor-related strategies, under certain conditions, lead to structural reforms. These strategies are ideational leadership or reform-enhancing blame-avoidance strategies, combined with two political-contextual conditions. Four set-theoretic hypotheses about combinations of the latter and structural reforms are examined, using fuzzy-set qualitative comparative analysis. The data include 16 reform cases in four continental welfare states that are notoriously hard to reform: Germany; Austria; the Netherlands; and France. The findings show that the two actor-related strategies matter for structural reform in combination, while contextual conditions function as their complements. Distant elections are indeed conducive to such reforms, while governments with a positive or negative welfare image achieve them along different paths: either combined with two strategies; or, when elections are distant, combined with ideational leadership or concession-making.
Bias and observation error characterization of the Fengyun-2F Stretched Visible and Infrared Spin Scan Radiometer with the aim of its radiance assimilation
Creators: name: Ren, Lu
name: Da, Cheng
name: Mengtao Yin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Recent studies start to explore the potential benefits of directly assimilating the radiance from the infrared imagers onboard geostationary satellites to the short-range numerical weather prediction both on the synoptic- and meso-scales, where accurate quantification of the bias and observation error arising from the numerical model and the instrument is a key component in such experiments. This paper investigates both the bias and the observation errors of the Stretched Visible and Infrared Spin Scan Radiometer (S-VISSR) onboard Chinese operational geostationary satellite Fengyun-2F, as the first step towards its clear-sky radiance assimilation. In this study, 774,530 observations that passed a five-step quality control procedure during the period of 1–7 July in 2014 are collected to investigate the mentioned two quantities while the synthetic simulated clear radiance is calculated through a numerical weather prediction model and a radiative transfer model. Persistent warm biases are found for FY-2 F S-VISSR channel 3, 4 and 5 during day and night, and they are possibly due to the uncertainty from the instrument calibration process. The observation errors of S-VISSR infrared channels vary with the surface types, generally with larger values over land than over ocean, which could partially be explained by the variation of the land types over land. Besides, whether these biases change with viewing geometry or evolve with time is also examined in our study. Biases from the three surface channels exhibit complex dependence on the scan position and evolve with time, which encourages incorporating both the scan position and temporal corrections into the S-VISSR bias correction scheme in the data assimilation system.
Bonding description of the Harpoon mechanism†
Creators: name: Rodríguez-Mayorga, Mauricio
name: Ramos-Cordoba, Eloy
name: Salvador, Pedro
name: Solà, Miquel
name: Matito, Eduard
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Marine Biology
subject: Hematology

description: The lowest lying states of LiH have been widely used to develop and calibrate many different methods in quantum mechanics. In this paper, we show that the electron-transfer processes occurring in these two states are a difficult test for chemical bonding descriptors and can be used to assess new bonding descriptors on its ability to recognise the harpoon mechanism. To this aim, we study the bond formation mechanism in a series of diatomic molecules. In all studied electron reorganisation mechanisms, the maximal electron-transfer variation point along the bond formation path occurs when about half electron has been transferred from one atom to another. If the process takes place through a harpoon mechanism, this point of the reaction path coincides with the avoided crossing. The electron sharing indices and one-dimensional plots of the electron localisation function and the Laplacian of the electron density along the molecular axis can be used to monitor the bond formation in diatomics and provide a distinction between the harpoon mechanism and a regular electron reorganisation process.
Bias and observation error characterization of the Fengyun-2F Stretched Visible and Infrared Spin Scan Radiometer with the aim of its radiance assimilation
Creators: name: Ren, Lu
name: Da, Cheng
name: Mengtao Yin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Recent studies start to explore the potential benefits of directly assimilating the radiance from the infrared imagers onboard geostationary satellites to the short-range numerical weather prediction both on the synoptic- and meso-scales, where accurate quantification of the bias and observation error arising from the numerical model and the instrument is a key component in such experiments. This paper investigates both the bias and the observation errors of the Stretched Visible and Infrared Spin Scan Radiometer (S-VISSR) onboard Chinese operational geostationary satellite Fengyun-2F, as the first step towards its clear-sky radiance assimilation. In this study, 774,530 observations that passed a five-step quality control procedure during the period of 1–7 July in 2014 are collected to investigate the mentioned two quantities while the synthetic simulated clear radiance is calculated through a numerical weather prediction model and a radiative transfer model. Persistent warm biases are found for FY-2 F S-VISSR channel 3, 4 and 5 during day and night, and they are possibly due to the uncertainty from the instrument calibration process. The observation errors of S-VISSR infrared channels vary with the surface types, generally with larger values over land than over ocean, which could partially be explained by the variation of the land types over land. Besides, whether these biases change with viewing geometry or evolve with time is also examined in our study. Biases from the three surface channels exhibit complex dependence on the scan position and evolve with time, which encourages incorporating both the scan position and temporal corrections into the S-VISSR bias correction scheme in the data assimilation system.
Designing supply contracts: buy-now, reserve, and wait-and-see
Creators: name: Jen-Yi Chen
name: Maqbool Dada
name: Qiaohai (Joice) Hu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: We consider three types of purchase contracts a manufacturer could offer in order to maximize its profit when supplying a retailer that uses responsive pricing to sell in an uncertain market: buy-now before the selling season starts, reserve stock for possible future purchase, and wait-and-see the market before making purchases. The existing literature has shown that adding a recourse purchase—i.e., the wait-and-see alternative—is always beneficial for the retailer who faces an uncertain demand. We find that this is not necessarily the case for the manufacturer who supplies the retailer, as its optimal contract mix depends on the market uncertainty as well as its production characteristics. The manufacturer should offer only the buy-now alternative if its recourse production is much more costly than advance production. As the recourse production cost decreases, the manufacturer should add a second contract to the portfolio: initially the reserve contract and then the wait-and-see contract. However, when the recourse production is cheaper than advance production, the manufacturer should drop the buy-now contract from the mix. As such, it is only in a small region, which shrinks with decreasing uncertainty in demand, that the manufacturer finds it optimal to offer all three purchasing alternatives.
Aquatic vegetation trends from 1992 to 2012 in Hamilton Harbour and Cootes Paradise, Lake Ontario
Creators: name: K. E. Leisti
name: T. Theÿsmeÿer
name: S. E. Doka
name: A. Court
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: Plant Biology

description: Over the past two hundred years, anthropogenic activities have resulted in the substantial decline of the once extensive wetlands in both Hamilton Harbour and Cootes Paradise. Some of the key stressors for aquatic vegetation have been infilling, sustained high water levels and level regulation in Lake Ontario, and reduced water clarity because of eutrophication and suspended sediments. Designated an Area of Concern in 1985, remediation efforts have included upgrades to the sewage treatment plants discharging into the harbour to reduce eutrophication and the 1996 construction of a fish barrier to exclude large Carp from entering Cootes Paradise to reduce turbidity. Over the past ten years, Cootes Paradise has seen a 120% increase in the areal extent of emergent vegetation, but this still represents less than 20% of the circa 1900's marsh area. Despite substantial reductions in Carp density in Cootes Paradise, submerged aquatic vegetation has been sparse and typically found at depths of less than 0.5 m, likely because of impaired light penetration. Following a significant improvement in water clarity in Hamilton Harbour between 1987 and 1997, submerged aquatic vegetation in the harbour proper expanded, achieving a mean maximum depth of 2.9 m in 2012. Species richness was considerably lower in Hamilton Harbour when compared to Cootes Paradise; however, the species composition in both these areas indicated degraded conditions throughout the time period of our assessment. Using our recent dataset, we tested relationships that had been previously established in the literature between emergent extent and water levels for Cootes Paradise and also the connection between maximum depth of submergent colonization and Secchi depths but simple univariate tests were not significant. A combination of small sample size, simple tests, and a small range for the independent variable may be issues in establishing simplified response relationships and are likely oversimplifications of vegetation response in the area that require more complex modelling.
Non-sequential and multi-step splicing of the dystrophin transcript
Creators: name: Gazzoli, Isabella
name: Pulyakhina, Irina
name: Verwey, Nisha E.
name: Ariyurek, Yavuz
name: Laros, Jeroen F. J.
name: Peter A. C. 'T Hoen
name: Aartsma-Rus, Annemieke
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal transcript to study different aspects of the human splicing process. Splicing is a complex process and much is unknown regarding the splicing of long introns in human genes. Here, we used ultra-deep transcript sequencing to characterize splicing of the dystrophin transcripts in 3 different human skeletal muscle cell lines, and explored the order of intron removal and multi-step splicing. Coverage and read pair analyses showed that around 40% of the introns were not always removed sequentially. Additionally, for the first time, we report that non-consecutive intron removal resulted in 3 or more joined exons which are flanked by unspliced introns and we defined these joined exons as an exon block. Lastly, computational and experimental data revealed that, for the majority of dystrophin introns, multistep splicing events are used to splice out a single intron. Overall, our data show for the first time in a human transcript, that multi-step intron removal is a general feature of mRNA splicing.
Non-sequential and multi-step splicing of the dystrophin transcript
Creators: name: Gazzoli, Isabella
name: Pulyakhina, Irina
name: Verwey, Nisha E.
name: Ariyurek, Yavuz
name: Laros, Jeroen F. J.
name: Peter A. C. 'T Hoen
name: Aartsma-Rus, Annemieke
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal transcript to study different aspects of the human splicing process. Splicing is a complex process and much is unknown regarding the splicing of long introns in human genes. Here, we used ultra-deep transcript sequencing to characterize splicing of the dystrophin transcripts in 3 different human skeletal muscle cell lines, and explored the order of intron removal and multi-step splicing. Coverage and read pair analyses showed that around 40% of the introns were not always removed sequentially. Additionally, for the first time, we report that non-consecutive intron removal resulted in 3 or more joined exons which are flanked by unspliced introns and we defined these joined exons as an exon block. Lastly, computational and experimental data revealed that, for the majority of dystrophin introns, multistep splicing events are used to splice out a single intron. Overall, our data show for the first time in a human transcript, that multi-step intron removal is a general feature of mRNA splicing.
Andriónico y el león: Digital edition
Creators: name: Miguel, Betti
name: Leblanc Elina
Publisher: name: Zenodo
Year: 2021
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2022), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Aquatic vegetation trends from 1992 to 2012 in Hamilton Harbour and Cootes Paradise, Lake Ontario
Creators: name: K. E. Leisti
name: T. Theÿsmeÿer
name: S.E. Doka
name: A. Court
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences

description: Over the past two hundred years, anthropogenic activities have resulted in the substantial decline of the once extensive wetlands in both Hamilton Harbour (HH) and Cootes Paradise (CP). Some of the key stressors for aquatic vegetation have been infilling, sustained high water levels and level regulation in Lake Ontario, and reduced water clarity because of eutrophication and suspended sediments. Designated an Area of Concern in 1985, remediation efforts have included upgrades to the sewage treatment plants discharging into the harbour to reduce eutrophication and the 1996 construction of a fish barrier to exclude large carp from entering CP to reduce turbidity. Over the past ten years, CP has seen a 120% increase in the areal extent of emergent vegetation, but this still represents less than 20% of the circa1900's marsh area. Despite substantial reductions in carp density in CP, submerged aquatic vegetation has been sparse and typically found at depths of less than 0.5 m, likely because of impaired light penetration.Following a significant improvement in water clarity in HH between 1987 and 1997, submerged aquatic vegetation in the harbour proper expanded, achieving a mean maximum depth of 2.9 m in 2012. Species richness was considerably lower in HH when compared to CP, however the species composition in both these areas indicated degraded conditions throughout the time period of our assessment. Using our recent dataset, we tested relationships that had been previously established in the literature between emergent extent and water levels for CP and also the connection between maximum depth of submergent colonization and Secchi depths but simple univariate tests were not significant. A combination of small sample size, simple tests, and a small range for the independent variable may be issues in establishing simplified response relationships and are likely oversimplifications of vegetation response in the area that require more complex modelling.
Designing Supply Contracts: Buy-Now, Reserve and Wait-And-See
Creators: name: Jen-Yi Chen
name: Maqbool Dada
name: Qiaohai Joice Hu
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Hematology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Chemistry
subject: Geology
subject: FOS: Earth and related environmental sciences

description: We consider three types of purchase contracts a manufacturer could offer in order to maximize its profit when supplying a retailer that uses responsive pricing to sell in an uncertain market: buy-now before the selling season starts, reserve stock for possible future purchase, and, wait-and-see the market before making purchases. The existing literature has shown that adding a recourse purchase, i.e, the wait-and-see alternative, is always beneficial for the retailer who faces an uncertain demand. We find that this is not necessarily the case for the manufacturer who supplies the retailer, as its optimal contract mix depends on the market uncertainty as well as its production characteristics. The manufacturer should offer only the buy-now alternative if its recourse production is much more costly than advance production. As the recourse production cost decreases, the manufacturer should add a second contract to the portfolio: initially the reserve contract and then the wait-and-see contract. However, when the recourse production is cheaper than advance production, the manufacturer should drop the buy-now contract from the mix. As such, it is only in a small region, which shrinks with decreasing uncertainty in demand, that the manufacturer finds it optimal to offer all three purchasing alternatives.
From the research on socially-sustainable agriculture (48)
Creators: name: Kwasek, Mariola
name: Maciejczak, Maciej
name: Wrzaszcz, Wioletta
name: Zegar, Józef Stanisław
name: Kwasek, Mariola (Ed.)
name: Zegar, Józef Stanisław (Ed.)
name: Kwasek, Mariola
name: Maciejczak, Maciej
name: Wrzaszcz, Wioletta
name: Zegar, Józef Stanisław
name: Kwasek, Mariola (Ed.)
name: Zegar, Józef Stanisław (Ed.)
Publisher: name: Unknown
Year: 2018
Subjects: subject: Agricultural and Food Policy
subject: Environmental Economics and Policy
subject: agriculture
subject: agriculture production
subject: family farm
subject: food system
subject: socially-sustainable agriculture
subject: sustainable food systems

description: Food systems and sustainable food systems. Non-industrial sustainable intensification of agriculture. Agriculture production potential and farms’ environmental sustainability – regional convergence or divergence?Sustainability of family farms by production and economic type in 2005 and 2016.
Andriónico y el león: Digital edition
Creators: name: Betti Miguel
name: Leblanc Elina
Publisher: name: Zenodo
Year: 2024
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Competition and solidarity: union members and immigration in Europe
Creators: name: Donnelly, Michael J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: This article addresses an understudied question in the comparative political economy of migration. How have trade unions shaped the attitudes of their members toward immigration? Unions are at the core of left-wing politics in most European countries, and support for immigration is usually a left-wing position. However, many of the core constituents of unions are those whose interests are most likely to be adversely affected by an increase in the supply of labour. The article shows that the pattern of European trade union leaders becoming supportive of open immigration policies has solidified over the past decade. It then provides evidence that this rhetoric has shaped the attitudes of union members and that the effect has become stronger over time. Finally, it shows that the effect is robust to the exclusion of countries where self-selection into unions on the basis of ideology is likely to be strongest.
Statistical downscaling of precipitation and temperature using sparse Bayesian learning, multiple linear regression and genetic programming frameworks
Creators: name: Joshi, Deepti
name: St-Hilaire, Andre
name: Ouarda, Taha
name: Anik Daigle
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Engineering

description: This study attempted to investigate two approaches to downscale temperature and four approaches to downscale precipitation. The first approach was an implementation of multiple linear regression (MLR) in the form of backward stepwise regression. The second approach applied canonical correlation analysis (CCA) with a sparse Bayesian learning (SBL) approach called relevance vector machine (RVM). For precipitation downscaling, two additional approaches which combined genetic programming (GP) as the predictor processing method with sparse Bayesian learning (SBLGP) and multiple linear regression (MLRGP) were also presented. The results showed that SBL outperformed MLR in downscaling temperature. For all stations, temperature was better downscaled than precipitation. For precipitation downscaling, the SBLGP approach outperformed all other approaches. MLRGP, on the other hand, did not bring about much improvement in the results and was in many cases outperformed by MLR.
Andriónico y el león: Digital edition
Creators: name: Betti Miguel
name: Leblanc Elina
Publisher: name: Zenodo
Year: 2022
Subjects: Spanish literature
Digital edition
XML-TEI

description: Digital edition of a Spanish pliego de cordel, published by the Andalusian printer José María Moreno (19th c.). It contains the XML-TEI file of the edition, as well as the files that led to this edition, i.e. the digital facsimiles (raw and retouched), and the transcription produced by the OCR tool Transkribus (PAGE-XML). This digital edition is a part of the research project Desenrollando el cordel / Untangling the cordel / Démêler le cordel (2020-2024), led by the professor Constance Carta at the University of Geneva and supported by the philanthropic Sandoz-Monique de Meuron Family Foundation.
Firsthand or secondhand data in school labs: It does not make a difference
Creators: name: Priemer, Burkhard
name: Pfeiler, Stephan
name: Ludwig, Tobias
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: 530 Physik

description: We report the findings of an empirical study that investigated whether the source of data—firsthand or secondhand data gained from lab work experiments—has an influence on students’ learning outcomes. Results indicate that students’ choice of a correct or incorrect hypothesis for a pendulum lab experiment on the influence of the mass of the bob on the time of oscillation does not depend on who the author of the data at hand is: the student themself, a peer, or a teacher. Further, students judge the importance of the data’s author as relatively unimportant no matter what data source they have at hand. Thus, it seems fairly unimportant whether students use firsthand or secondhand data when the teaching focus is set on choosing a correct hypothesis in the light of empirical data, as long as students get enough information on how the data were generated and how they are analyzed and interpreted. This result is especially relevant for practitioners, as it shows that it is possible to use secondhand data for the purpose of evaluation and interpretation without significant distortions of epistemic learning processes.
Physicochemical characterisation and cyclodextrin complexation of erlotinib
Creators: name: Gergő Tóth
name: Jánoska, Ádám
name: Zoltán-István Szabó
name: Völgyi, Gergely
name: Orgován, Gábor
name: Szente, Lajos
name: Noszál, Béla
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Erlotinib (ERL), the anticancer drug of poor bioavailability, was quantified in terms of bio-relevant physicochemical parameters, such as acid–base properties, lipophilicity and solubility, and a comprehensive study on its inclusion complexation was carried out. The protonation constant of ERL (log K = 5.32) indicates that it exists mainly in deprotonated form at the pH of blood plasma. The high lipophilicity (log p = 2.75) explains its good permeability, while the very low solubility (S0 = 12.46 μM) causes its low bioavailability and renders injection formulation a difficult job. This problem could be alleviated by enhancing ERL solubility through cyclodextrin (CD) inclusion complexation. Therefore, ERL–CD interactions were studied by a number of analytical techniques. The apparent stability constants of ERL with seven different CDs were determined using affinity capillary electrophoresis. Results indicated that the seven-membered β-CD and its derivatives were the most suitable hosts. Using UV Job plot titration 1:1 stoichiometry was determined, confirmed by electrospray ionisation-mass spectrometry experiments. The geometry of the inclusion complex was investigated by 2D ROESY NMR techniques, revealing that the ethynylphenyl ring enters the β-CD cavity. Phase-solubility analysis shows greatly enhanced solution concentration by CD complexation. The determined equilibrium and structural information offer molecular basis to elaborate improved drug formulation with enhanced bioavailability.
Double π-hole tetrel-chalcogen interactions can lead to stable molecular heterodimer
Creators: name: E. L. Zins
name: M. E. Alikhani
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: A thorough topological investigation is used to study the possible isomers of (SO3)(H2XY) complexes, for X=C, Si and Y=O, S. From the topological properties of the isolated monomers, up to five types of isomers can be considered, depending on the nature of the X and Y atoms. After geometry optimisations, three isomers belonging to four different types of geometry were obtained. The natures of the X and Y atoms not only affect the relative stability of the isomers, but also the interaction sites available on the H2XY molecule. For all the systems considered in this study, a covalent structure was obtained from a non-covalent isomeric form involving a double π-hole interaction. Such a covalent structure corresponds to the global minimum for the (SO3)(H2CS), (SO3)(H2SiO) and (SO3)(H2SiS) complexes, and a local minimum for the (SO3)(H2CO) complex. The usefulness of physically-relevant topological tools for a thorough characterisation of the monomers prior to a search for the isomeric forms of a complex is once again demonstrated.
MPEC 2024-E67 : 2024 DY1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 DY1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Benzophenone and zinc(II) phthalocyanine dichromophores-labeled poly (aryl ether) dendrimer: synthesis, characterization and photoinduced energy transfer
Creators: name: Pan, Su-Juan
name: Ma, Dong-Dong
name: Liu, Jian-Sheng
name: Chen, Kui-Zhi
name: Zhang, Tian-Tian
name: Peng, Yi-Ru
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Computational Biology

description: A series of benzophenone chromospheres and zinc(II) phthalocyanine dichromophores labeled poly (aryl benzyl ether) dendrimer (Gn-DZnPc(BP)8n, n = 1−2) were synthesized. Their structures were characterized by elemental analysis, 1H NMR, IR, UV–vis and matrix-assisted laser desorption/ionization time-of-flight spectrometry (MALDI-TOF MS). Their photophysical properties were examined by steady-state and time-resolved fluorescence methods. Both the poly (aryl benzyl ether) dendrimer and BP terminal chromophores had a significant effect on photophysical properties of the zinc(II) phthalocyanine core. Time-resolved spectroscopic measurements indicated that the lifetime of benzophenone (donor) chromophore was longer than that of the zinc(II) phthalocyanine (acceptor). The fluorescence of the peripheral benzophenone chromophores was quenched by the phthalocyanine group attached to the focal point. All of these observations suggest that an intramolecular singlet energy transfer occurs in Gn-DZnPc(BP)8n molecules. The light-harvesting abilities of these molecules increased with generations due to an increase in the number of benzophenone chromophores. The energy transfer efficiencies were ca. 0.49 and 0.68 for generations 1 and 2, respectively, and the rate constants of the singlet-singlet energy transfer were ca. 108 s−1. The rate constants changed inconspicuously with increase of dendron generations. The intramolecular singlet-singlet energy transfer is proposed to proceed mainly via a Förster-type interaction mechanism involving the dendrimer backbone as a scaffold to hold the peripheral benzophenone chromophores and the phthalocyanine core together. This dendrimer was an effective new energy transmission complex with high efficiency and could be used as a potential light-harvesting system.
Supplemental Information from Phase-change-mediated transport and agglomeration of fungal spores on wheat awns
Creators: name: Iliff, Grady J.
name: Mukherjee, Ranit
name: Gruszewski, Hope A.
name: Schmale, David G.
name: Jung, Sunghwan
name: Boreyko, Jonathan B.
Publisher: name: The Royal Society
Year: 2022
Subjects: subject: Biophysics
subject: 110601 Biomechanics
subject: FOS: Health sciences

description: Identification of fungus, four supporting figures, one supporting table, and three supporting video captions.
Residual plots for linear regression models with censored outcome data: A refined method for visualizing residual uncertainty
Creators: name: Law, Martin
name: Jackson, Dan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Residual plots are a standard tool for assessing model fit. When some outcome data are censored, standard residual plots become less appropriate. Here, we develop a new procedure for producing residual plots for linear regression models where some or all of the outcome data are censored. We implement two approaches for incorporating parameter uncertainty. We illustrate our methodology by examining the model fit for an analysis of bacterial load data from a trial for chronic obstructive pulmonary disease. Simulated datasets show that the method can be used when the outcome data consist of a variety of types of censoring.
title: Wie wirkt sich mehrmaliges Kompetenz-Feedback auf psychotherapeutische Behandlungen aus?
title: How does multiple competence feedback affect psychotherapeutic treatment?
title: eine qualitative Analyse
titleType: Subtitle
title: a qualitative analysis
titleType: Subtitle
Creators: name: Kaufmann, Yvonne M.
name: Maiwald, Lisa
name: Schindler, Svenja
name: Weck, Florian
Publisher: name: Universität Potsdam
Year: 2020

description: Theoretischer Hintergrund: Einflüsse von therapeutenorientiertem Kompetenz-Feedback in der Psychotherapieausbildung wurden bislang wenig untersucht. Fragestellung: Wie gehen Ausbildungstherapeuten mit Feedback um? Welchen Einfluss hat ein regelmäßiges Kompetenz-Feedback auf die Qualität psychotherapeutischer Behandlungen (insbesondere Therapiesitzungen, therapeutische Beziehung, Person des Therapeuten, Supervision)? Methode: Elf Therapeuten wurden mithilfe eines halbstrukturierten Interviewleitfadens befragt. Die Auswertung erfolgte mittels qualitativer Inhaltsanalyse nach Mayring (2015). Ergebnisse: Das auf Basis der Interviews erstellte Kategoriensystem umfasste die Kategorien „Erwartungen an das Feedback“, „Wahrnehmung des Feedbacks“, „Verarbeitung von und Umgang mit Feedback“, „Folgen, Auswirkungen und Veränderungen durch Feedback“ sowie „Verbesserungswünsche“. Schlussfolgerungen: Therapeuten streben eine Umsetzung des Feedbacks an, welches sich auf die Behandlung, die Supervision, die eigene Person und die therapeutische Beziehung auswirkt.
description: Background: To date, the influence of therapist-oriented feedback in psychotherapy training has rarely been investigated. Objective: How do therapists in training deal with competence feedback? What influence does a regular competence feedback have on treatment quality (especially therapy sessions, therapeutic alliance, the therapist, supervision)? Method: We interviewed 11 therapists using a semistructured interview guide. The text material was analyzed with qualitative content analysis (Mayring, 2015). Results: The interview-based system of categories consists of: expectations toward feedback; perception of feedback; processing of feedback; consequences, effects, and changes due to feedback; and suggestions for improvement. Conclusion: Therapists strive to implement feedback. Competence feedback has an impact on treatment, supervision, the therapist, and the therapeutic alliance.
description: Postprints der Universität Potsdam : Humanwissenschaftliche Reihe, 614
MPEC 2024-E68 : 2024 EQ1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 EQ1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Benzophenone and zinc(II) phthalocyanine dichromophores labeled poly (aryl ether) dendrimer: Synthesis, characterization and photoinduced energy transfer
Creators: name: Zhang, Tian-Tian
name: Pan, Su-Juan
name: Ma, Dong-Dong
name: Liu, Jian-Sheng
name: Chen, Kui-Zhi
name: Peng, Yi-Ru
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Physiology
subject: Cell Biology
subject: Physics
subject: Biochemistry
subject: Biophysics

description: A series of benzophenone chromospheres and zinc(II) phthalocyanine dichromophores labeled poly (aryl benzyl ether) dendrimer (Gn-DZnPc(BP)8n, n=1-2) were synthesized. Their structures were characterized by elemental analysis, 1H NMR, IR, UV-Vis and matrix-assisted laser desorption/ionization time-of-flight spectrometry (MALDI-TOF MS). Their photophysical properties were examined by steady-state and time-resolved fluorescence methods. Both the poly (aryl benzyl ether) dendrimer and BP terminal chromophores had a significant effect on photophysical properties of the zinc(II) phthalocyanine core. Time-resolved spectroscopic measurements indicated that the lifetime of benzophenone (donor) chromophore was longer than that of the zinc(II) phthalocyanine (acceptor). The fluorescence of the peripheral benzophenone chromophores was quenched by the phthalocyanine group attached to the focal point. All of these observations suggest that an intramolecular singlet energy transfer occurs in Gn-DZnPc(BP)8n molecules. The light-harvesting abilities of these molecules increased with generations due to an increase in the number of benzophenone chromophores. The energy transfer efficiencies were ca. 0.49 and 0.68 for generations 1 and 2, respectively, and the rate constants of the singlet-singlet energy transfer were ca. 108 s−1. The rate constants changed inconspicuously with increase of dendron generations. The intramolecular singlet-singlet energy transfer is proposed to proceed mainly via a Förster-type interaction mechanism involving the dendrimer backbone as a scaffold to hold the peripheral benzophenone chromophores and the phthalocyanine core together. This dendrimer was an effective new energy transmission complex with high efficiency and could be used as a potential light-harvesting system.
Conservation Theatre: Mirroring Experiences and Performing Stories in Community Management of Natural Resources
Creators: name: Heras, María
name: J. David Tàbara
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Learning how to boost collective imagination and creativity is a key component in transformative processes supporting community-based natural resource management (CBNRM). The use of the arts in such contexts is becoming a prominent methodological approach in strategies aimed at opening new spaces for public dialogue and reflection. The arts play a decisive role in sense-making and especially in establishing meaningful and emotional connections between individuals and their broader socioecological systems. This article explores the contribution of “conservation theatre” to sustainability learning and to the integration and mobilization of multiple knowledge actors for CBNRM. We focus on an experience in a Mexican community using participatory theatre with young people. Our experience illustrates that conservation theatre helped raise awareness of local conservation issues and contributed to opening nonconventional, aesthetically rich spaces for new ways of social interaction, diversity recognition, and empathic dialogues. It also showed limitations suggesting the importance of further work.
Comprehensive Cost Analysis of the 2014 Massachusetts MS4 Permit
Creators: name: Correia, Eric
name: Giroux, Michael
name: Peterson, Cameron
Publisher: name: QUBES Educational Resources
Year: 2025

description: Stormwater runoff is one of the leading causes of water pollution in the United States. The MS4 permit reduces pollution by regulating the runoff of pollutants into stormwater drains. With the assistance of the MassDEP and the Worcester Community Project Center, we sought to provide the Massachusetts towns of Southbridge, Holden, and Millbury with a cost analysis for implementation of the 2014 draft MS4 permit. In order to achieve this goal, we learned the details of the 2003 permit and 2014 draft permit, interviewed town officials, and performed water quality sampling. After creating our cost analysis, we provided our subject towns with findings and recommendations assessing the feasibility of implementing the permit, and suggestions for best practices each town uses to manage stormwater.
title: Zürcher Zunft-Historien
title: Schilderungen aus der Geschichte Zürichs
titleType: Subtitle
Creators: name: Gyr, Salomon Friedrich
Publisher: name: Verlag des Zentral-Komitees der Zünfte Zürichs; Buchdruckerei Berichthaus
Year: 1929
Subjects: subject: 949 Geschichte anderer Teile Europas
subject: Zürich
subject: Zunft
subject: Gesellschaft zur Constaffel
subject: Zunft zur Saffran (Zürich)
subject: Zunft zur Meisen (Zürich)
subject: Zunft zur Schmiden
subject: Zunft zum Weggen
subject: Zunft zur Gerwe und zur Schuhmachern
subject: Zunft zum Widder
subject: Zunft zur Zimmerleuten
subject: Zunft zur Schneidern
subject: Zunft zur Schiffleuten
subject: Zunft zum Kämbel (Zürich)
subject: Zunft zur Waag (Zürich)
subject: Gesellschaft der Schildner zum Schneggen
subject: Gesellschaft der Bogenschützen Zürich
subject: Stadtzunft Zürich
subject: Zunft Riesbach
subject: Zunft Fluntern
subject: Zunft zu den Drei Königen
subject: Zunft Hottingen
subject: Zunft zu Wiedikon
subject: Zunft Wollishofen
subject: Zunft Hard (Zürich)
subject: Zunft zu Oberstrass

description: Im Auftrage des Zentral-Komitees der Zünfte Zürichs aufgezeichnet von Salomon Friedrich Gyr. Mit 3 Stadtplänen, 5 Tafelbeilagen, 25 Wappen in Farbendruck, zusammen 290 Text-Illustrationen.
title: TBS-TK Rezension
title: CBCL/6-18R, TRF/6-18R, YSR/11-18R. Deutsche Schulalter-Formen der Child Behavior Checklist von Thomas M. Achenbach. Elternfragebogen über das Verhalten von Kindern und Jugendlichen (CBCL/6-18R), Lehrerfragebogen über das Verhalten von Kindern und Jugendlichen (TRF/6-18R), Fragebogen für Jugendliche (YSR/11-18R)
titleType: Subtitle
Creators: name: Esser, Günter
name: Hänsch-Oelgart, Sylvana
name: Schmitz, Julian
Publisher: name: Universität Potsdam
Year: 2020

description: Postprints der Universität Potsdam : Humanwissenschaftliche Reihe, 615
Residual Plots for Linear Regression Models with Censored Outcome Data: A Refined Method for Visualising Residual Uncertainty
Creators: name: Law, Martin
name: Jackson, Dan
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biotechnology
subject: Medicine

description: Residual plots are a standard tool for assessing model fit. When some outcome data are censored, standard residual plots become less appropriate. Here we develop a new procedure for producing residual plots for linear regression models where some or all of the outcome data are censored. We implement two approaches for incorporating parameter uncertainty. We illustrate our methodology by examining the model fit for an analysis of bacterial load data from a trial for chronic obstructive pulmonary disease. Simulated datasets show that the method can be used when the outcome data consist of a variety of types of censoring.