cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Gallium arsenide waveguides as a platform for direct mid-infrared vibrational spectroscop
Creators: name: Haas, Julian
name: Stach, Robert
name: Kolm, Claudia
name: Krska, Rudolf
name: Mizaikoff, Boris
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Surface modification
subject: Evanescent field absorption
subject: Self-assembled monolayers
subject: Surface-enhanced infrared absorption
subject: Mid-infrared chem/biosensor
subject: DDC 540 / Chemistry & allied sciences
subject: Gallium arsenide
subject: Galliumarsenid

description: During recent years, mid-infrared (MIR) spectroscopy has matured into a versatile and powerful sensing tool for a wide variety of analytical sensing tasks. Attenuated total reflection (ATR) techniques have gained increased interest due to their potential to perform non-destructive sensing tasks close to real time. In ATR, the essential component is the sampling interface, i.e., the ATR waveguide and its material properties interfacing the sample with the evanescent field ensuring efficient photon-molecule interaction. Gallium arsenide (GaAs) is a versatile alternative material vs. commonly used ATR waveguide materials including but not limited to silicon, zinc selenide, and diamond. GaAs-based internal reflection elements (IREs) are a new generation of semiconductor-based waveguides and are herein used for the first time in direct spectroscopic applications combined with conventional Fourier transform infrared (FT-IR) spectroscopy. Next to the characterization of the ATR waveguide, exemplary surface reactions were monitored, and trace-level analyte detection via signal amplification taking advantage of surface-enhanced infrared absorption (SEIRA) effects was demonstrated. As an example of real-world relevance, the mycotoxin aflatoxin B1 (AFB1) was used as a model analyte in food and feed safety analysis.
The future of basic science in orthopaedics and traumatology: Cassandra or Prometheus?
Creators: name: Madry, Henning
name: Grässel, Susanne
name: Nöth, Ulrich
name: Relja, Borna
name: Bernstein, Anke
name: Docheva, Denitsa
name: Kauther, Max Daniel
name: Katthagen, Jan Christoph
name: Bader, Rainer
name: Van Griensven, Martijn
name: Wirtz, Dieter C.
name: Raschke, Michael J.
name: Huber-Lang, Markus
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Basic science
subject: Orthopaedics
subject: Traumatology
subject: Research agenda
subject: Needs
subject: Future
subject: DDC 610 / Medicine & health

description: Abstract Orthopaedic and trauma research is a gateway to better health and mobility, reflecting the ever-increasing and complex burden of musculoskeletal diseases and injuries in Germany, Europe and worldwide. Basic science in orthopaedics and traumatology addresses the complete organism down to the molecule among an entire life of musculoskeletal mobility. Reflecting the complex and intertwined underlying mechanisms, cooperative research in this field has discovered important mechanisms on the molecular, cellular and organ levels, which subsequently led to innovative diagnostic and therapeutic strategies that reduced individual suffering as well as the burden on the society. However, research efforts are considerably threatened by economical pressures on clinicians and scientists, growing obstacles for urgently needed translational animal research, and insufficient funding. Although sophisticated science is feasible and realized in ever more individual research groups, a main goal of the multidisciplinary members of the Basic Science Section of the German Society for Orthopaedics and Trauma Surgery is to generate overarching structures and networks to answer to the growing clinical needs. The future of basic science in orthopaedics and traumatology can only be managed by an even more intensified exchange between basic scientists and clinicians while fuelling enthusiasm of talented junior scientists and clinicians. Prioritized future projects will master a broad range of opportunities from artificial intelligence, gene- and nano-technologies to large-scale, multi-centre clinical studies. Like Prometheus in the ancient Greek myth, transferring the elucidating knowledge from basic science to the real (clinical) world will reduce the individual suffering from orthopaedic diseases and trauma as well as their socio-economic impact.
Reactions of a 3‐phenyl‐1‐trifluoromethyl‐prop‐2‐yne iminium salt with furans, thiophenes, and pyrroles
Creators: name: Schneider, Thomas
name: Heinrich, Georg
name: Koch, Raphael
name: Maas, Gerhard
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Five-membered heteroaromatics
subject: Iminium salts
subject: DDC 540 / Chemistry & allied sciences
subject: Alkynes
subject: Ring formation (Chemistry)
subject: Organofluorine compounds
subject: Alkine
subject: Cyclisation
subject: Fluororganische Verbindungen

description: Reactions of a novel propyne iminium salt, N,N-dimethyl 3-phenyl-1-trifluoromethyl-propyne iminium triflate, with electron-rich heteroaromatic ring systems (furans, thiophenes, pyrroles) are reported. The 1-CF3-propyne iminium ion can act as a highly reactive ambident electrophile, giving rise to simple electrophilic heteroaromatic ring substitution products, and as a 1,3-biselectrophile leading to C2+C3-CF3 annulation products. Reactions of a novel propyne iminium salt, N,N-dimethyl 3-phenyl-1-trifluoromethyl-propyne iminium triflate, with electron-rich heteroaromatic ring systems (furans, thiophenes, pyrroles) are reported. The 1-CF3-propyne iminium ion can act as a highly reactive ambident electrophile, giving rise to simple electrophilic heteroaromatic ring substitution products, and as a 1,3-biselectrophile leading to C2+C3-CF3 annulation products. Moreover, it is an electron-deficient alkyne which was found to afford double [2+2] cycloaddition products with 2,5-dimethylfuran and 2,5-dimethylthiophene. The obtained molecular structures include CF3-containing compounds with cyclopenta[b]furan, cyclopenta[b]thiophene, cyclopenta[c]thiophene, cyclopenta[b]pyrrole, cyclopenta[c]pyrrole, 3H-pyrrolizine, and 1,4-dihydrocyclopenta[b]pyrrole ring systems. Analogous reactions of 1,3(or 1,4)-phenylenebis(1-CF3-propyne iminium) salts with furans, pyrroles or thiophenes in a 2 : 1 stoichiometry lead to phenylene-tethered condensed heterocycles of the same type.
The Whitehaven Pier Saltpans 1632-86 and their Accounts 1675-77.
Creators: name: Tyson, Blake
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 195-220
description: Gathers evidence for a salt-production site omitted from a recent survey. Documentary evidence locates extant elements of the site, which are recommended for listing. The economic fortunes of salt-making in the area are described, with particular reference to competition from Cheshire. There is an `Appendix: Rowland Jackson's advice on salt pans c. 1631' (215).
Archbishop Grindal's birthplace: Cross Hill, St Bees, Cumbria.
Creators: name: Todd, John M
name: Todd, Mary
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 185-194
description: Born between 1517 and 1520, and 19 and 20 Finkle Street A.K.A. Cross Hill. A note on `The fabric of 19/20 Cross Hill, St Bees' by Paul Barker (189--2). See also 2000/762.
Calibration of passive samplers for the monitoring of pharmaceuticals in water – sampling rate variation
Creators: name: Męczykowska, Hanna
name: Kobylis, Paulina
name: Stepnowski, Piotr
name: Caban, Magda
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Passive sampling is one of the most efficient methods of monitoring pharmaceuticals in environmental water. The reliability of the process relies on a correctly performed calibration experiment and a well-defined sampling rate (Rs) for target analytes. Therefore, in this review the state-of-the-art methods of passive sampler calibration for the most popular pharmaceuticals: antibiotics, hormones, β-blockers and nonsteroidal anti-inflammatory drugs (NSAIDs), along with the sampling rate variation, were presented. The advantages and difficulties in laboratory and field calibration were pointed out, according to the needs of control of the exact conditions. Sampling rate calculating equations and all the factors affecting the Rs value - temperature, flow, pH, salinity of the donor phase and biofouling were discussed. Moreover, various calibration parameters gathered from the literature published in the last 16 years, including the device types, were tabled and compared. What is evident is that the sampling rate values for pharmaceuticals are impacted by several factors, whose influence is still unclear and unpredictable, while there is a big gap in experimental data. It appears that the calibration procedure needs to be improved, e.g. there is a significant deficiency of PRCs (Performance Reference Compounds) for pharmaceuticals. One of the suggestions is to introduce correction factors for Rs values estimated in laboratory conditions.
Carbon Footprint Reduction for Sustainable Data Centers in Real-Time
Creators: name: Sarkar, Soumyendu
name: Naug, Avisek
name: Luna, Ricardo
name: Guillen, Antonio
name: Gundecha, Vineet
name: Ghorbanpour, Sahand
name: Mousavi, Sajad
name: Markovikj, Dejan
name: Babu, Ashwin Ramesh
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Multiagent Systems (cs.MA)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: As machine learning workloads significantly increase energy consumption, sustainable data centers with low carbon emissions are becoming a top priority for governments and corporations worldwide. This requires a paradigm shift in optimizing power consumption in cooling and IT loads, shifting flexible loads based on the availability of renewable energy in the power grid, and leveraging battery storage from the uninterrupted power supply in data centers, using collaborative agents. The complex association between these optimization strategies and their dependencies on variable external factors like weather and the power grid carbon intensity makes this a hard problem. Currently, a real-time controller to optimize all these goals simultaneously in a dynamic real-world setting is lacking. We propose a Data Center Carbon Footprint Reduction (DC-CFR) multi-agent Reinforcement Learning (MARL) framework that optimizes data centers for the multiple objectives of carbon footprint reduction, energy consumption, and energy cost. The results show that the DC-CFR MARL agents effectively resolved the complex interdependencies in optimizing cooling, load shifting, and energy storage in real-time for various locations under real-world dynamic weather and grid carbon intensity conditions. DC-CFR significantly outperformed the industry standard ASHRAE controller with a considerable reduction in carbon emissions (14.5%), energy usage (14.4%), and energy cost (13.7%) when evaluated over one year across multiple geographical regions.
Cumbrian wall paintings.
Creators: name: Burkett, Mary E
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 159-176
description: Details late medieval wall and ceiling paintings from the county, using the late-fifteenth- to early-sixteenth-century ceiling at Prior's Room in Carlisle Cathedral precinct as a benchmark for other, more fragmentary, works. Sites include Archbishop Grindal's birthplace (see 2000/853). Oriental, Classical and Christian influences can be seen in the various motifs.
Chemical analysis of Gothic mortar from a bridge pier in Roudnice nad Labem (Czech Republic)
Creators: name: Stepanka Kuckova
name: Jiri Santrucek
name: Adamec, Martin
name: Hynek, Radovan
name: Zeman, Antonin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry

description: In this paper, a Gothic mortar originating from the remains of a bridge pier in Roudnice nad Labem (Czech Republic) was analyzed. The inorganic composition of the mortar showing special mechanical properties was studied using polarizing light microscopy, scanning electron microscopy coupled with energy dispersive X-ray spectrometry, and X-ray diffraction, while the protein content was analyzed by peptide mass mapping using matrix-assisted laser desorption/ionization—time of flight mass spectrometry and nanoliquid chromatography coupled to tandem mass spectrometry. Two types of inorganic binders having a composition similar to mineral wollastonite and hydraulic lime and milk protein additive were detected. We believe that organic and inorganic binders added together to the mortar increase its hardness and firmness in the aquatic environment.
HIV-1 Pr55Gag binds genomic and spliced RNAs with different affinity and stoichiometry
Creators: name: Bernacchi, Serena
name: Ekram W. Abd El-Wahab
name: Dubois, Noé
name: Hijnen, Marcel
name: Smyth, Redmond P.
name: Mak, Johnson
name: Marquet, Roland
name: Jean-Christophe Paillart
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: The HIV-1 Pr55Gag precursor specifically selects genomic RNA (gRNA) from a large variety of cellular and spliced viral RNAs (svRNAs), however the molecular mechanisms of this selective recognition remains poorly understood. To gain better understanding of this process, we analyzed the interactions between Pr55Gag and a large panel of viral RNA (vRNA) fragments encompassing the main packaging signal (Psi) and its flanking regions by fluorescence spectroscopy. We showed that the gRNA harbors a high affinity binding site which is absent from svRNA species, suggesting that this site might be crucial for selecting the HIV-1 genome. Our stoichiometry analysis of protein/RNA complexes revealed that few copies of Pr55Gag specifically associate with the 5′ region of the gRNA. Besides, we found that gRNA dimerization significantly impacts Pr55Gag binding, and we confirmed that the internal loop of stem-loop 1 (SL1) in Psi is crucial for specific interaction with Pr55Gag. Our analysis of gRNA fragments of different length supports the existence of a long-range tertiary interaction involving sequences upstream and downstream of the Psi region. This long-range interaction might promote optimal exposure of SL1 for efficient Pr55Gag recognition. Altogether, our results shed light on the molecular mechanisms allowing the specific selection of gRNA by Pr55Gag among a variety of svRNAs, all harboring SL1 in their first common exon.
Роль почвы в циркуляции макро- и микроэлементов между живыми организмами в изолированных замкнутых экосистемах
Creators: name: Юницкий А.Э.
name: Налётов И.В.
name: Заяц В.С.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: гормоны щитовидной железы
здоровье человека
передача минеральных элементов
почва
содержание минеральных элементов
ферменты
ЭкоКосмоДом (ЭКД)

description: Почва является основным источником макро- и микроэлементов, циркулирующих в замкнутой экосистеме. Все элементы, находящиеся в почве, поступают в растения, откуда дальше без изменений или в результате метаболических превращений передаются на более высокие трофические уровни. В данной статье оценивается роль почвы (с участием растений как промежуточной стадии) в доставке жизненно важных элементов человеку и животным. Предлагается методика осуществления эксперимента на лабораторных животных по изучению передачи элементов на примере селена, йода, меди.
Excavation of Medieval settlement remains at Crosedale in Howgill
Creators: name: Hair, Nick J
name: Newman, Rachel
name: Howard-Davis, Christine L E
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 141-158
description: Small, sub-rectangular enclosure surveyed in 1994 and excavated in 1995. `The finds' by Christine Howard-Davis (149--51) are sparse, mostly medieval (and possibly early medieval) pottery and iron blade fragments. There is a note on the `Historical context' by Caron Newman (151--3). The favoured interpretation is that it represents a medieval scale, occupied sporadically during the summer for up to 200 years and possibly established as part of a monastic bercary system organised by Cockersand Abbey.
Cumulative genetic score of DRD2 polymorphisms is associated with impulsivity and masked semantic priming
Creators: name: Sanwald, Simon
name: Montag, Christian
name: Kiefer, Markus
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Semantic priming
subject: Impulsivity
subject: DRD2
subject: DDC 570 / Life sciences
subject: Dopamine
subject: Impulsive Behavior
subject: Executive Function
subject: Dopamin
subject: Impulsivität
subject: Exekutive Funktionen

description: Individual differences in the magnitude of semantic priming effects are associated with executive functions (EF). Striatal dopamine has been shown to be associated with EF as well as impulsivity and could therefore be associated with differences in the magnitude of semantic priming. We investigated n = 155 individuals in an unmasked as well as in a masked semantic priming paradigm. We additionally assessed self-reported impulsivity and a cumulative genetic score (CGS) comprising six polymorphisms that have been found to be functionally relevant for the expression of the DRD2 gene. We found a significantly negative association between the DRD2 CGS and reaction time priming in the masked semantic priming paradigm. In addition, the DRD2 CGS was positively associated with self-reported impulsivity. Our findings complement previous research by showing a role of the DRD2 gene for masked semantic priming. Therefore, the investigation of genes within the dopamine system might improve our understanding of the genetic basis of impulsivity and semantic processing. Thus, the DRD2 CGS is of interest for clinical as well as experimental psychological research.
Historical development of Annetwell Street, Carlisle.
Creators: name: Jones, B C
Publisher: name: Archaeology Data Service
Year: 2002

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 99, 129-140
description: A discussion on the tenurial development of Annetwell Street, prepared as a contribution to the final report on the excavations on the south side of the Street, initiated in 1973 by Dorothy Charlesworth and completed by Ian Caruana. As the site itself was primarily Roman, this report is presented as a free-standing paper. There is a note on `The archaeology of the site' by Ian Caruana (136--8).
Создание математической модели общепланетарного транспортного средства с оптимизацией положения и учётом влияния динамических факторов
Creators: name: Юницкий А.Э.
name: Шаршов Р.А.
name: Абакумов А.А.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: общепланетарное транспортное средство (ОТС)
конструкция ОТС
динамика
оптимизация
расчётный случай

description: Представлен расчёт математической модели общепланетарного транспортного средства (ОТС) с введением дополнительных факторов, которые позволят более полно оценить полётные характеристики конструкции. На первом этапе добавляется двухфакторная оптимизация: учитывается фактическая неровность земной поверхности; оценивается плоскопараллельное смещение конструкции ОТС относительно экватора для выбора приемлемого положения и учёта появляющейся дополнительной горизонтальной силы. На втором этапе принимаются во внимание динамические факторы, возникающие в зависимости от положения ОТС и влияющие на поведение конструкции при взлёте. Приведено решение и сделаны выводы о целесообразности смещения ОТС и его оптимальном положении, а также о возможности взлёта ОТС под влиянием фактических неровностей земной поверхности.
How to be fair? A study of label and selection bias
Creators: name: Favier, Marco
name: Calders, Toon
name: Pinxteren, Sam
name: Meyer, Jonathan
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: It is widely accepted that biased data leads to biased and thus potentially unfair models. Therefore, several measures for bias in data and model predictions have been proposed, as well as bias mitigation techniques whose aim is to learn models that are fair by design. Despite the myriad of mitigation techniques developed in the past decade, however, it is still poorly understood under what circumstances which methods work. Recently, Wick et al. showed, with experiments on synthetic data, that there exist situations in which bias mitigation techniques lead to more accurate models when measured on unbiased data. Nevertheless, in the absence of a thorough mathematical analysis, it remains unclear which techniques are effective under what circumstances. We propose to address this problem by establishing relationships between the type of bias and the effectiveness of a mitigation technique, where we categorize the mitigation techniques by the bias measure they optimize. In this paper we illustrate this principle for label and selection bias on the one hand, and demographic parity and ``We're All Equal'' on the other hand. Our theoretical analysis allows to explain the results of Wick et al. and we also show that there are situations where minimizing fairness measures does not result in the fairest possible distribution.
title: OFROM: interview avec unine15b02m
Creators: name: Delafontaine, François
name: Rothenbühler, Julie
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.deb5q5ob.v2#7cef3b7b65325b457be70ccb3443273ff6c1697a
SAVE ENERGY OUTCOMES
Creators: name: Cowley, Benjamin
Publisher: name: figshare
Year: 2016
Subjects: subject: 160703 Social Program Evaluation
subject: FOS: Sociology

description: D7.7 SAVE ENERGY Best Practices describes the evaluation of every project pilot, and the serious game (i.e. the preliminary version of the associated paper). It also provides a recommendation for other projects to implement energy efficiency initiatives.
SAVE ENERGY Green Paper is a policy document at European level describing an approach toward energy efficiency through behaviour change.
SAVE ENERGY Manual is a more practical document to help implement an approach toward energy efficiency through behaviour change.
Технико-экономическое обоснование инвестиционного проекта «Безракетная индустриализация ближнего космоса» как инструмента спасения биосферы Земли
Creators: name: Юницкий А.Э.
name: Бабаян А.В.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: космический вектор индустриального развития
общепланетарное транспортное средство (ОТС)
технико-экономическое обоснование (ТЭО)
биосфера Земли
техносфера Земли

description: Проект «Безракетная индустриализация ближнего космоса» – глобальный инвестиционный проект, способный предотвратить планетарную экологическую катастрофу и обеспечить будущее земной технократической цивилизации. Стремительное наращивание космической индустриальной мощи является не только существенным фактором его инвестиционного успеха, но и скорейшего достижения им стратегической цели – конкурентного устранения отраслей техносферы Земли, оказывающих угнетающее воздействие на биосферу. Полномасштабный и одновременно быстрый характер индустриализации космоса предъявляет высокие требования к показателям экономической эффективности и грузоподъёмности общепланетарного транспортного средства (ОТС) инженера А.Э. Юницкого. В рамках всестороннего технико-экономического обоснования данного проекта сформулированы принципиально важные организационные и экономические условия хозяйствования для его участников; построена расчётная модель, позволяющая оценивать показатели эффективности ОТС в широком диапазоне режимов транспортной нагрузки; представлены выводы.
Diagnostic reliability of the Berlin classification for complex MCA aneurysms—usability in a series of only giant aneurysms
Creators: name: Wessels, Lars
name: Fekonja, Lucius Samo
name: Achberger, Johannes
name: Dengler, Julius
name: Czabanka, Marcus
name: Hecht, Nils
name: Schneider, Ulf
name: Tkatschenko, Dimitri
name: Schebesch, Karl-Michael
name: Schmidt, Nils Ole
name: Mielke, Dorothee
name: Hosch, Henning
name: Ganslandt, Oliver
name: Gräwe, Alexander
name: Hong, Bujung
name: Walter, Jan
name: Güresir, Erdem
name: Bijlenga, Philippe
name: Haemmerli, Julien
name: Maldaner, Nicolai
name: Marbacher, Serge
name: Nurminen, Ville
name: Zitek, Hynek
name: Dammers, Ruben
name: Kato, Naoki
name: Linfante, Italo
name: Pedro, Maria-Teresa
name: Wrede, Karsten
name: Wang, Wei-Te
name: Wostrack, Maria
name: Vajkoczy, Peter
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Giant aneurysm
subject: Cerebral bypass
subject: MCA aneurysm
subject: DDC 610 / Medicine & health

description: Abstract Background and objective The main challenge of bypass surgery of complex MCA aneurysms is not the selection of the bypass type but the initial decision-making of how to exclude the affected vessel segment from circulation. To this end, we have previously proposed a classification for complex MCA aneurysms based on the preoperative angiography. The current study aimed to validate this new classification and assess its diagnostic reliability using the giant aneurysm registry as an independent data set. Methods We reviewed the pretreatment neuroimaging of 51 patients with giant (> 2.5 cm) MCA aneurysms from 18 centers, prospectively entered into the international giant aneurysm registry. We classified the aneurysms according to our previously proposed Berlin classification for complex MCA aneurysms. To test for interrater diagnostic reliability, the data set was reviewed by four independent observers. Results We were able to classify all 51 aneurysms according to the Berlin classification for complex MCA aneurysms. Eight percent of the aneurysm were classified as type 1a, 14% as type 1b, 14% as type 2a, 24% as type 2b, 33% as type 2c, and 8% as type 3. The interrater reliability was moderate with Fleiss’s Kappa of 0.419. Conclusion The recently published Berlin classification for complex MCA aneurysms showed diagnostic reliability, independent of the observer when applied to the MCA aneurysms of the international giant aneurysm registry.
Техносфера 2.1 – перезагрузка земной индустрии на космический вектор развития
Creators: name: Юницкий А.Э.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: космическое индустриальное ожерелье «Орбита» (КИО «Орбита»)
линейный город
перезагрузка техносферы
общепланетарное транспортное средство (ОТС)
Струнный транспорт Юницкого (СТЮ
или UST)
техногенная цивилизация
техносфера 2.1
TransNet
цивилизационная развилка
ЭкоКосмоДом (ЭКД)

description: Вопросы глобальных проблем современности и устойчивого развития человечества всегда волновали прогрессивные умы. Однако наше будущее нельзя достоверно спрогнозировать, не проанализировав с помощью инженерной логики всю историю становления земной технократии, кардинально отличающейся от чисто биологической цивилизации, например цивилизации дельфинов. Автор статьи насчитал пять технологических эпох. От первой, когда древние инженеры изобрели огонь и с его помощью стали готовить пищу, до нынешних дней, когда в качестве альтернативы грядущей гибели нашей цивилизации на Земле предлагается освоить чужой и далёкий Марс. Разграбив, загадив, отравив и убив свой родной дом, нам предлагается построить новый там, где нет биосферы земного типа и где люди погибнут по историческим меркам мгновенно. Автор ввёл понятие «цивилизационная техногенная развилка», согласно которому сегодня у человечества действительно есть выбор. Или через два поколения прийти к точке невозврата, к своей деградации, угасанию и гибели. Или осуществить неракетную индустриализацию ближнего космоса, решить все экологические проблемы на Земле, превратив планету в цветущий сад, где комфортно и безопасно смогут жить и трудиться до 25 млрд человек.
Экологические биоразлагаемые материалы на бумажной основе и их использование в условиях замкнутых экосистем
Creators: name: Курдюкова Т.О.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: биоразлагаемые материалы
вторичное сырьё
переработка бумаги
производство бумаги
утилизация

description: Жизнь в изолированном пространстве с ограниченной площадью, к которому могут относиться замкнутые экосистемы, ставит перед человеком задачи другого уровня, отличные от земных. В первую очередь новая среда диктует жителям необходимость самостоятельного обеспечения себя всем нужным для комфортного и продуктивного существования. Значит, следует внимательно подойти к перечню того, что действительно важно иметь человеку для полноценной жизни; какие площади, ресурсы и время потребуются для производства этих вещей; каким образом их можно утилизировать или перерабатывать в условиях замкнутых циклов автономной биосферы. В представленной работе рассматриваются обязательные для жителей замкнутой экосистемы предметы быта и труда, выполненные из экологических биоразлагаемых материалов на бумажной основе, а также выпуск данных материалов не только для повседневного употребления, но и в медицинских целях, например для стерилизации медицинских инструментов. Кроме того, в настоящей статье обоснована целесообразность использования экологических биоразлагаемых материалов на бумажной основе, показаны направления их применения, способы изготовления, переработки и утилизации.
Exploring ChatGPT and its Impact on Society
Creators: name: Haque, Md. Asraful
name: Li, Shuai
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computers and Society (cs.CY)
subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences
subject: 68Txx

description: Artificial intelligence has been around for a while, but suddenly it has received more attention than ever before. Thanks to innovations from companies like Google, Microsoft, Meta, and other major brands in technology. OpenAI, though, has triggered the button with its ground-breaking invention ChatGPT. ChatGPT is a Large Language Model (LLM) based on Transformer architecture that has the ability to generate human-like responses in a conversational context. It uses deep learning algorithms to generate natural language responses to input text. Its large number of parameters, contextual generation, and open-domain training make it a versatile and effective tool for a wide range of applications, from chatbots to customer service to language translation. It has the potential to revolutionize various industries and transform the way we interact with technology. However, the use of ChatGPT has also raised several concerns, including ethical, social, and employment challenges, which must be carefully considered to ensure the responsible use of this technology. The article provides an overview of ChatGPT, delving into its architecture and training process. It highlights the potential impacts of ChatGPT on the society. In this paper, we suggest some approaches involving technology, regulation, education, and ethics in an effort to maximize ChatGPT's benefits while minimizing its negative impacts. This study is expected to contribute to a greater understanding of ChatGPT and aid in predicting the potential changes it may bring about.
description: 13 Pages
Эстафетный принцип радиосвязи для прогнозирования и предотвращения грозящих человечеству катастроф в дальнем космосе
Creators: name: Плескачевский Ю.М.
Publisher: name: Сборник материалов III международной научно-технической конференции «Безракетная индустриализация ближнего космоса: проблемы, идеи, проекты»
Year: 2020
Subjects: дальний космос
«дозоры» в виде космических лабораторий
предотвращение катастроф
траектория движения Земли
угрозы для человечества
эстафетный принцип радиосвязи

description: Систематизированы все известные траектории движения в космосе Земли, Солнечной системы и Галактики. Названы и кратко описаны вероятные на этих путях угрозы для человечества. Предложено запускать с определёнными интервалами впереди движущейся Земли «дозоры» в виде «моделей» нашей планеты, содержащие комплекс космических лабораторий, которые по эстафетному принципу от «модели» к «модели» и далее будут передавать информацию Земле о гравитационных, радиационных, физических и биологических жизненно важных явлениях и процессах. Человечество сможет своевременно принять меры по предотвращению возможных катастроф.
A Pilot Randomized Controlled Trial of a Brief Conflict Reappraisal Intervention for Community Couples with Young Children
Creators: name: Wade, Mark
name: Markwell, Alexandra
name: Koven, Maya
name: Jambon, Marc
name: Muise, Amy
name: Prime, Heather
Publisher: name: OSF Registries
Year: 2024

description: Accepted Paper (March 28, 2024): Cognitive Therapy and Research (Springer Journal)
Figure S3. Relationships between substratum inclination and depth in the observed 10 × 40-m quadrat at Kasenga point, southern Lake Tanganyika. Different letters on the boxes indicate significant differences at 5% by Tukey's test. from Depth and substratum differentiations among coexisting herbivorous cichlids in Lake Tanganyika
Creators: name: Hata, Hiroki
name: Ochi, Haruki
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Cichlid fish in Lake Tanganyika represent a system of adaptive radiation in which eight ancestral lineages have diversified into hundreds of species through adaptation to various niches. However, Tanganyikan cichlids have been thought to be oversaturated, that is, the species number exceeds the number of niches and ecologically equivalent and competitively even species coexist. However, recent studies have shed light on niche segregation on a finer scale among apparently equivalent species. We observed depth and substratum preferences of 15 herbivorous cichlids from four ecomorphs (i.e. grazer, browser, scraper and scooper) on a rocky littoral slope for 14 years. Depth differentiation was detected among grazers that defended feeding territories and among browsers with feeding territories. Cichlid species having no feeding territory also showed specificity on depth and substratum, resulting in habitat segregation among species that belong to the same ecomorph. Phylogenetically close species did not occupy adjacent depths, nor the opposite depth zones. Our findings suggest that apparently equivalent species of the same ecomorph coexist parapatrically along depth on a few metre scale, or coexist with different substratum preferences on the rocky shore, and this niche segregation may have been acquired by competition between encountering equivalent species through repetitive lake-level fluctuations.
The RTS,S/AS01 malaria vaccine in children 5 to 17 months of age at first vaccination
Creators: name: Vandoolaeghe, Pascale
name: Lode Schuerman
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology

description: The RTS,S/AS01 malaria vaccine received a positive scientific opinion from the European Medicines Agency in July 2015. The World Health Organization recommended pilot implementation of the vaccine in children at least 5 months of age according to an initial 3-dose schedule given at least 1 month apart, and a 4th dose 15–18 months post-dose 3. Clinical trials and mathematical modeling demonstrated that the partial protection provided by RTS,S/AS01 against malaria has the potential to provide substantial public health benefit when used in parallel with other malaria interventions, especially in highly endemic regions. The highest impact was seen with 4 vaccine doses in children aged 5 months or older. The vaccine will be evaluated in real-life settings to further assess its impact on mortality, vaccine safety in the context of routine immunization, and programmatic feasibility of delivering a 4-dose vaccination schedule requiring new immunization contacts. If successful, this will pave the way for larger-scale implementation.
Table S1. Generalised linear mixed model of the density of grazing herbivorous cichlids. Cichlid species, depth, substratum type, and inclination of substratum were analysed as fixed factors with survey year as a random factor. Std. Error = standard error. from Depth and substratum differentiations among coexisting herbivorous cichlids in Lake Tanganyika
Creators: name: Hata, Hiroki
name: Ochi, Haruki
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Cichlid fish in Lake Tanganyika represent a system of adaptive radiation in which eight ancestral lineages have diversified into hundreds of species through adaptation to various niches. However, Tanganyikan cichlids have been thought to be oversaturated, that is, the species number exceeds the number of niches and ecologically equivalent and competitively even species coexist. However, recent studies have shed light on niche segregation on a finer scale among apparently equivalent species. We observed depth and substratum preferences of 15 herbivorous cichlids from four ecomorphs (i.e. grazer, browser, scraper and scooper) on a rocky littoral slope for 14 years. Depth differentiation was detected among grazers that defended feeding territories and among browsers with feeding territories. Cichlid species having no feeding territory also showed specificity on depth and substratum, resulting in habitat segregation among species that belong to the same ecomorph. Phylogenetically close species did not occupy adjacent depths, nor the opposite depth zones. Our findings suggest that apparently equivalent species of the same ecomorph coexist parapatrically along depth on a few metre scale, or coexist with different substratum preferences on the rocky shore, and this niche segregation may have been acquired by competition between encountering equivalent species through repetitive lake-level fluctuations.
Figure S2. Box plot of depth variation of substratum types in the observed 10 × 40-m quadrat at Kasenga point, southern Lake Tanganyika. Different letters on the boxes indicate significant differences at 5% by Tukey's test. from Depth and substratum differentiations among coexisting herbivorous cichlids in Lake Tanganyika
Creators: name: Hata, Hiroki
name: Ochi, Haruki
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Cichlid fish in Lake Tanganyika represent a system of adaptive radiation in which eight ancestral lineages have diversified into hundreds of species through adaptation to various niches. However, Tanganyikan cichlids have been thought to be oversaturated, that is, the species number exceeds the number of niches and ecologically equivalent and competitively even species coexist. However, recent studies have shed light on niche segregation on a finer scale among apparently equivalent species. We observed depth and substratum preferences of 15 herbivorous cichlids from four ecomorphs (i.e. grazer, browser, scraper and scooper) on a rocky littoral slope for 14 years. Depth differentiation was detected among grazers that defended feeding territories and among browsers with feeding territories. Cichlid species having no feeding territory also showed specificity on depth and substratum, resulting in habitat segregation among species that belong to the same ecomorph. Phylogenetically close species did not occupy adjacent depths, nor the opposite depth zones. Our findings suggest that apparently equivalent species of the same ecomorph coexist parapatrically along depth on a few metre scale, or coexist with different substratum preferences on the rocky shore, and this niche segregation may have been acquired by competition between encountering equivalent species through repetitive lake-level fluctuations.
Salivary beta-endorphin in nonsuicidal self-injury: an ambulatory assessment study
Creators: name: Störkel, Lisa M.
name: Karabatsiakis, Alexander
name: Hepp, Johanna
name: Kolassa, Iris-Tatjana
name: Schmahl, Christian
name: Niedtfeld, Inga
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Diagnostic markers
subject: Peptides
subject: BORDERLINE PERSONALITY-DISORDER
subject: ENDOGENOUS OPIOIDS
subject: STRESS
subject: DYSREGULATION
subject: PREVALENCE
subject: DIMENSION
subject: BEHAVIOR
subject: RECEPTOR
subject: TESTS
subject: HARM
subject: DDC 150 / Psychology

description: Abstract Nonsuicidal self-injury (NSSI) is a prevalent and impairing behavior, affecting individuals with and without additional psychopathology. To shed further light on biological processes that precede and result from NSSI acts, we built on previous cross-sectional evidence suggesting that the endogenous opioid system, and especially β-endorphin, is involved in the psychopathology of NSSI. This is the first study assessing salivary β-endorphin in daily life in the context of NSSI acts. Fifty-one female adults with repetitive NSSI participated over a period of 15 days in an ambulatory assessment study. Salivary β-endorphin was assessed before and after engagement in NSSI, during high urge for NSSI, and on a non-NSSI day. Furthermore, NSSI specific variables such as pain ratings, as well as method, severity, and function of NSSI were assessed. We found that β-endorphin levels immediately before an NSSI act were significantly lower than directly after NSSI. However, there was no difference between β-endorphin during high urge for NSSI and post NSSI measures. We found a positive association between severity of the self-inflicted injury and β-endorphin levels, but no significant association between β-endorphin levels and subjectively experienced pain. The results of the present study indicate that it is possible to assess salivary β-endorphin in daily life in the context of NSSI. Furthermore, our results provide a first indication that NSSI acts could be associated with a momentary increase of β-endorphin, and this might reinforce NSSI engagement. More research is needed to replicate and extend our findings on peripheral β-endorphin in daily life.
Radiotherapy in nodal oligorecurrent prostate cancer
Creators: name: Pinkawa, Michael
name: Aebersold, Daniel M.
name: Böhmer, Dirk
name: Flentje, Michael
name: Ghadjar, Pirus
name: Schmidt-Hegemann, Nina-Sophie
name: Höcht, Stefan
name: Hölscher, Tobias
name: Müller, Arndt-Christian
name: Niehoff, Peter
name: Sedlmayer, Felix
name: Wolf, Frank
name: Zamboglou, Constantinos
name: Zips, Daniel
name: Wiegel, Thomas
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Prostate cancer
subject: Oligorecurrence
subject: Metastasis-directed therapy
subject: Radiation therapy
subject: Androgen deprivation therapy
subject: Stereotactic body radiotherapy
subject: Oligmometastases
subject: Lymph node metastases
subject: DDC 610 / Medicine & health

description: Abstract Objective The current article encompasses a literature review and recommendations for radiotherapy in nodal oligorecurrent prostate cancer. Materials and methods A literature review focused on studies comparing metastasis-directed stereotactic ablative radiotherapy (SABR) vs. external elective nodal radiotherapy (ENRT) and studies analyzing recurrence patterns after local nodal treatment was performed. The DEGRO Prostate Cancer Expert Panel discussed the results and developed treatment recommendations. Results Metastasis-directed radiotherapy results in high local control (often > 90% within a follow-up of 1–2 years) and can be used to improve progression-free survival or defer androgen deprivation therapy (ADT) according to prospective randomized phase II data. Distant progression after involved-node SABR only occurs within a few months in the majority of patients. ENRT improves metastases-free survival rates with increased toxicity in comparison to SABR according to retrospective comparative studies. The majority of nodal recurrences after initial local treatment of pelvic nodal metastasis are detected within the true pelvis and common iliac vessels. Conclusion ENRT with or without a boost should be preferred to SABR in pelvic nodal recurrences. In oligometastatic prostate cancer with distant (extrapelvic) nodal recurrences, SABR alone can be performed in selected cases. Application of additional systemic treatments should be based on current guidelines, with ADT as first-line treatment for hormone-sensitive prostate cancer. Only in carefully selected patients can radiotherapy be initially used without additional ADT outside of the current standard recommendations. Results of (randomized) prospective studies are needed for definitive recommendations.