cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: A systematic method of retrofit of urban residential buildings for design, decision and policymaking in Chongqing, China
Creators: name: Han, Shiyu
Publisher: name: University of Reading
Year: 2023

description: Energy consumption and carbon emission have become a challenge in old residences in China. Old residential buildings remain dilapidated with their poorly insulated building façade and significant potential in energy and carbon conservation. Yet the current circumstances are found very complicated due to the unclear reality and complex nature of the diversities of building conditions, resident preferences, economy, and social factors of coordination and motivation. Retrofit of urban residential buildings (RURB) is treated not as a systematic research topic, but rather as a project-based construction process in current knowledge. This linear thinking has been argued which caused empiricism problems since interconnections between retrofit system participants are notably neglected. To achieve the research objectives and justify the system thinking perspective, this thesis explores and understands the system cognition and interactions of the Retrofit of Urban Residential Buildings (RURB). The adopted system thinking method, interviews, and questionnaire survey methods are used based on causal layered analysis for the comprehensive system definition, boundary, variables, and participants. System interactions between system players and variables are also analysed by using the causal loop diagram method, hence systemic problems can be discovered. With this theoretical basis, a case study of the Chongqing city zone is selected to support the system theory with urban retrofit effects. Results of retrofitting benefits and costs are obtained through modelling, field survey, energy simulation, and calculation approaches. They are evaluated as five retrofit criteria of energy, cost, comfort, function, and safety improvements. A total of the six retrofit scenarios with four referencing building types are applied to multi-criteria decision�making analysis, as the analytic network process for the weighted values of retrofit benefits and costs. The retrofitting potential, solutions for systemic problems, and hence the suggestions for future policymaking are found and discussed. This research develops an innovative and coherent method to support future RURB decision-making and policymaking by providing both a theoretical basis and reliable data source, which can become a generalised approach to RURB analysis in other city conditions.
title: Herpesvirusinfektionen bei schwerstverbrannten Kindern
Creators: name: Wurzer, P.
name: Branski, L. K.
name: Cambiaso-Daniel, J.
name: Tuca, A.-C.
name: Cole, M.
name: Clayton, R. P.
name: Lopez Nunez, O.
name: Winter, R.
name: Kamolz, L.-P.
name: Herndon, D. N.
name: Finnerty, C. C.
name: Lee, J. O.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Der immunsupprimierte Status des schwerstverbrannten Patienten macht ihn anfälliger für bakterielle als auch virale Infektionen. Herpesvirusinfektionen und ihre Auswirkung auf die Dauer des Krankenhausaufenthaltes und Wundheilung wurden im erwachsenen Verbrennungspatienten beschrieben.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Hormone-dependent control of developmental timing through regulation of chromatin accessibility
Creators: name: Uyehara, Christopher M.
name: Buttitta, Laura A.
name: Ma, Yiqin
name: McKay, Daniel J.
name: Nystrom, Spencer L.
name: Niederhuber, Matthew J.
name: Leatham-Jensen, Mary
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Specification of tissue identity during development requires precise coordination of gene expression in both space and time. Spatially, master regulatory transcription factors are required to control tissue-specific gene expression programs. However, the mechanisms controlling how tissue-specific gene expression changes over time are less well understood. Here, we show that hormone-induced transcription factors control temporal gene expression by regulating the accessibility of DNA regulatory elements. Using the Drosophila wing, we demonstrate that temporal changes in gene expression are accompanied by genome-wide changes in chromatin accessibility at temporal-specific enhancers. We also uncover a temporal cascade of transcription factors following a pulse of the steroid hormone ecdysone such that different times in wing development can be defined by distinct combinations of hormone-induced transcription factors. Finally, we show that the ecdysone-induced transcription factor E93 controls temporal identity by directly regulating chromatin accessibility across the genome. Notably, we found that E93 controls enhancer activity through three different modalities, including promoting accessibility of late-acting enhancers and decreasing accessibility of early-acting enhancers. Together, this work supports a model in which an extrinsic signal triggers an intrinsic transcription factor cascade that drives development forward in time through regulation of chromatin accessibility.
Modulation of macrophage differentiation and activation by paracrine signals from cardiac progenitor cells
Creators: name: Samari, Sara
Publisher: name: Imperial College London
Year: 2022

description: Myocardial infarction (MI) triggers an inflammatory response that contributes to cardiac remodelling in adult mice. In contrast, the heart of the post-MI neonatal mouse regenerates without scarring due to an anti-inflammatory macrophage-dependent process. Previously, Noseda and colleagues demonstrated that intramyocardial injection of Lin-Sca1+CD31-PDGFRalpha+SP+ cardiac progenitor/stem cells (CSCs) improved cardiac function. However, despite the lack of long-term engraftment, the cardiac improvement could be explained by paracrine factors released by CSCs. The paracrine effects of CSCs could affect several cell types in the heart, including macrophages. Therefore, this PhD thesis hypothesises that CSCs release paracrine factors that promote a subtype of anti-inflammatory macrophage phenotype to support cardiac regeneration. After flow sorting, single F4/80+CD11b+ macrophages were analysed by single qRT PCR. GM-CSF+LPS+IFNγ-driven M, identified as CX3CR1+CD11b+F4/80loCD206-, co-expressed pro-inflammatory genes, Nos2, Cxcl9, Cxcl10 and Il-6. On the other hand, M-CSF+IL-4+IL-13-driven Mf identified as CX3CR1+CD11b+F4/80+CD206+, upregulated anti-inflammatory genes, Arg1, Angpt2, and Igf1. Notably, CSCs conditioned media (CSC CondM)-driven macrophages were indistinguishable from M-CSF+IL-4+IL-13-Mf. Lastly, CSC CondM+IL4+IL13-driven M group was identified as CX3CR1+CD11b+F4/80+CD206+, expressing Arg1, Angptl2, Igf1, Il1rl1, and Mrc1, and showing a distinct subtype of anti-inflammatory macrophage phenotype compared to all prior reports of anti-inflammatory/M2-like macrophages. After confirming that CSCs secrete M-CSF (20pg/mL) as the potential protective factor, the M-CSF/CSF1R pathway was inhibited by using first the pharmacological inhibitor BLZ945 and then a monoclonal antibody against CSF1R. These inhibitory experiments demonstrated that the inhibition of M-CSF activity reduced cell viability, the percentage of F4/80+CD11b+CX3CR1+CD206+ macrophages, expression of anti-inflammatory and pro-fibrotic genes (Arg1, Angpt2, Igf1, Il1rl1, Mrc1 and Gdf15), and phagocytosis activity. Multiplex bead-based flow immunoassays also showed that CSC CondM+LPS+IFN-Mf secrete IL-10 depending upon the M-CSF/CSF1R pathway. In conclusion, CSC-secreted M-CSF is the indispensable paracrine factor that induces macrophages with an anti-inflammatory phenotype. In conclusion, CSC-secreted M-CSF is the indispensable paracrine factor that induces macrophages with an anti-inflammatory phenotype.
Gene expression profile of pulpitis
Creators: name: Henson,
name: Parker,
name: Khan,
name: Galicia,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The cost, prevalence and pain associated with endodontic disease necessitate an understanding of the fundamental molecular aspects of its pathogenesis. This study was aimed to identify the genetic contributors to pulpal pain and inflammation. Inflamed pulps were collected from patients diagnosed with irreversible pulpitis (n=20). Normal pulps from teeth extracted for various reasons served as controls (n=20). Pain level was assessed using a visual analog scale (VAS). Genome-wide microarray analysis was performed using Affymetrix GeneTitan Multichannel Instrument. The difference in gene expression levels were determined by the Significance Analysis of Microarray program using a false discovery rate (q-value) of 5%. Genes involved in immune response, cytokine-cytokine receptor interaction and signaling, integrin cell surface interactions, and others were expressed at relatively higher levels in the in the pulpitis group. Moreover, several genes known to modulate pain and inflammation showed differential expression in asymptomatic and mild pain patients (≥30mm on VAS) compared to those with moderate to severe pain. This exploratory study provides a molecular basis for the clinical diagnosis of pulpitis. With an enhanced understanding of pulpal inflammation, future studies on treatment and management of pulpitis and on pain associated with it can have a biological reference to bridge treatment strategies with pulpal biology.
Rapid cosmic-ray acceleration at perpendicular shocks in supernova remnants
Creators: name: Takamoto, Makoto
name: Kirk, John G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Perpendicular shocks are shown to be rapid particle accelerators that perform optimally when the ratio $u_{\rm s}$ of the shock speed to the particle speed roughly equals the ratio $1/η$ of the scattering rate to the gyro frequency. We use analytical methods and Monte-Carlo simulations to solve the kinetic equation that governs the anisotropy generated at these shocks, and find, for $ηu_{\rm s}\approx1$, that the spectral index softens by unity and the acceleration time increases by a factor of two compared to the standard result of diffusive shock acceleration theory. These results provide a theoretical basis for the thirty-year-old conjecture that a supernova exploding into the wind of a Wolf-Rayet star may accelerate protons to an energy exceeding $10^{15}\,$eV.
description: 12 pages, 2 figures, accepted for publication in ApJ
A fingerprint based metric for measuring similarities of crystalline structures
Creators: name: Zhu, Li
name: Amsler, Maximilian
name: Fuhrer, Tobias
name: Schaefer, Bastian
name: Faraji, Somayeh
name: Rostami, Samare
name: Ghasemi, S. Alireza
name: Sadeghi, Ali
name: Grauzinyte, Migle
name: Wolverton, Christopher
name: Goedecker, Stefan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Measuring similarities/dissimilarities between atomic structures is important for the exploration of potential energy landscapes. However, the cell vectors together with the coordinates of the atoms, which are generally used to describe periodic systems, are quantities not suitable as fingerprints to distinguish structures. Based on a characterization of the local environment of all atoms in a cell we introduce crystal fingerprints that can be calculated easily and allow to define configurational distances between crystalline structures that satisfy the mathematical properties of a metric. This distance between two configurations is a measure of their similarity/dissimilarity and it allows in particular to distinguish structures. The new method is an useful tool within various energy landscape exploration schemes, such as minima hopping, random search, swarm intelligence algorithms and high-throughput screenings.
Sonnenfleckenzeichnung Nr. 149.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.06.1984, 07:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
On the rotation of co-orbital bodies in eccentric orbits
Creators: name: Leleu, A.
name: Robutel, P.
name: Correia, A. C. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We investigate the resonant rotation of co-orbital bodies in eccentric and planar orbits. We develop a simple analytical model to study the impact of the eccentricity and orbital perturbations on the spin dynamics. This model is relevant in the entire domain of horseshoe and tadpole orbit, for moderate eccentricities. We show that there are three different families of spin-orbit resonances, one depending on the eccentricity, one depending on the orbital libration frequency, and another depending on the pericenter's dynamics. We can estimate the width and the location of the different resonant islands in the phase space, predicting which are the more likely to capture the spin of the rotating body. In some regions of the phase space the resonant islands may overlap, giving rise to chaotic rotation.
Sonnenfleckenzeichnung Nr. 34.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.02.1984, 09:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Geometric distortions in clinical MRI sequences for radiotherapy: insights gained from a multicenter investigation
Creators: name: Hasler, Signe Winther
name: Kallehauge, Jesper Folsted
name: Hansen, Rasmus Hvass
name: Samsøe, Eva
name: Arp, Dennis Tideman
name: Nissen, Henrik Dahl
name: Edmund, Jens M.
name: Bernchou, Uffe
name: Mahmood, Faisal
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Mental Health

description: As magnetic resonance imaging (MRI) becomes increasingly integrated into radiotherapy (RT) for enhanced treatment planning and adaptation, the inherent geometric distortion in acquired MR images pose a potential challenge to treatment accuracy. This study aimed to evaluate the geometric distortion levels in the clinical MRI protocols used across Danish RT centers and discuss influence of specific sequence parameters. Based on the variety in geometric performance across centers, we assess if harmonization of MRI sequences is a relevant measure. Nine centers participated with 12 MRI scanners and MRI-Linacs (MRL). Using a travelling phantom approach, a reference MRI sequence was used to assess variation in baseline distortion level between scanners. The phantom was also scanned with local clinical MRI sequences for brain, head/neck (H/N), abdomen, and pelvis. The influence of echo time, receiver bandwidth, image weighting, and 2D/3D acquisition was investigated. We found a large variation in geometric accuracy across 93 clinical sequences examined, exceeding the baseline variation found between MRI scanners (σ = 0.22 mm), except for abdominal sequences where the variation was lower. Brain and abdominal sequences showed lowest distortion levels ([0.22, 2.26] mm), and a large variation in performance was found for H/N and pelvic sequences ([0.19, 4.07] mm). Post hoc analyses revealed that distortion levels decreased with increasing bandwidth and a less clear increase in distortion levels with increasing echo time. 3D MRI sequences had lower distortion levels than 2D (median of 1.10 and 2.10 mm, respectively), and in DWI sequences, the echo-planar imaging read-out resulted in highest distortion levels. There is a large variation in the geometric distortion levels of clinical MRI sequences across Danish RT centers, and between anatomical sites. The large variation observed makes harmonization of MRI sequences across institutions and adoption of practices from well-performing anatomical sites, a relevant measure within RT.
Upper mantle seismic anisotropy in the eastern Mediterranean and seismicity in Cyprus
Creators: name: Merry, Thomas Alexander Johnstone
Publisher: name: Imperial College London
Year: 2022

description: This thesis concerns the tectonics and geodynamics of the eastern Mediterranean, a zone of terminal-stage ocean basin closure between Eurasia and Africa, through two seismological investigations. First, large-scale mantle deformation related to the tectonics of Anatolia and complex subduction dynamics is investigated. Some have suggested the westward tectonic motion of Anatolia is linked to a similar deep flow in the asthenospheric mantle; however, several smaller-scale geodynamic processes may instead dominate the asthenospheric flow field, including slab break-off, slab tearing, and lithospheric delamination. I investigate the relative importance of these processes through measuring upper mantle seismic anisotropy via SKS shear-wave splitting analysis. Spatial variations in direction and strength of anisotropy attest to the influence of the complex slab architecture and multiple geodynamic processes on mantle flow. Additionally, lithospheric anisotropy in a mantle shear zone beneath the North Anatolian Fault is revealed for the first time. Subsequently, I study seismicity in Cyprus associated with proposed incipient continental collision and the uplift of the Troodos ophiolite. I combine manual and automated techniques to identify and pick P- and S-phase arrivals for local earthquakes during a 2-year period and present a method to remove quarry blasts from the catalogue. I constrain 1-D seismic velocity models for earthquake location and present a new local magnitude scale. I interpret the earthquake locations with new and existing focal mechanisms in terms of the tectonic setting. There is evidence for active subduction of the Eratosthenes seamount beneath Cyprus, with earthquakes associated with the dehydration of the downgoing plate and with intra- slab deformation. A lack of seismicity in a 20 km-wide zone at the peak of the seamount is likely associated with fluid focusing that causes high-degree serpentinisation of the overlying Troodos mantle, providing the first seismological evidence of a deep root to the Mt. Olympus serpentinite diapir.
Genetic basis for variation in plasma IL-18 levels in persons with chronic hepatitis C virus and human immunodeficiency virus-1 infections
Creators: name: Peters,
name: Thomas,
name: Young,
name: Busch,
name: Aouizerat,
name: Thio,
name: Gustafson,
name: Mehta,
name: Vergara,
name: Eron,
name: Golub,
name: Kirk,
name: Villacres,
name: Anastos,
name: Latanich,
name: Kim,
name: Murphy,
name: Lauer,
name: Lahiri,
name: Cox,
name: Shrestha,
name: Duggal,
name: French,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Inflammasomes are multi-protein complexes integrating pathogen-triggered signaling leading to the generation of pro-inflammatory cytokines, including interleukin-18 (IL-18). Hepatitis C virus (HCV) and human immunodeficiency virus-1 (HIV) infections are associated with elevated IL-18, suggesting inflammasome activation. However, there is marked person-to-person variation in the inflammasome response to HCV and HIV. We hypothesized that host genetics may explain this variation. To test this, we analyzed the associations of plasma IL-18 levels and polymorphisms in 10 genes in the inflammasome cascade. 1538 participants with active HIV and/or HCV infection in 3 ancestry groups are included. Samples were genotyped using the Illumina Omni 1-quad and Omni 2.5 arrays. Linear regression analyses were performed to test the association of variants with logIL-18 including HCV and HIV infection status and HIV-RNA, in each ancestry group and then meta-analyzed. Eleven highly correlated SNPs (r2=0.98-1) in the IL18-BCO2 region were significantly associated with logIL-18; Each T allele of rs80011693 confers a decrease of 0.06 log pg/mL of IL-18 after adjusting for covariates (rs80011693; rs111311302 β-0.06, P-value=2.7×10-4). In conclusion, genetic variation in IL18 is associated with IL-18 production in response to HIV and HCV infection and may explain variability in the inflammatory outcomes of chronic viral infections.
title: Off-label NexoBrid use for enzymatic burn debridement in children
Creators: name: Müller-Kühnle, J.
name: Busch, J.
name: Hülße, B.
name: Bodenschatz, K.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Up to date only limited options are available in the initial wound management of severe burns in children. There is evidence for enzymatic wound debridement with the bromelain containing substance NexoBrid™ in adults, but this treatment is still classified as off-label use in children. For this[for full text, please go to the a.m. URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 144.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.06.1984, 07:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Korrelation zwischen invasiver und nicht invasiver Blutdruckmessung in schwerverbrannten Kindern
Creators: name: Cambiaso-Daniel, J.
name: Smolle, C.
name: Wurzer, P.
name: Winter, R.
name: Branski, L.
name: Herndon, D. N.
name: Lumenta, D. B.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Genaue Blutdruckmessung ist ein essentieller Bestandteil des Monitorings in der Verbrennungstherapie. Derzeit ist die invasive (intraarterielle) Blutdruckmessung der Goldstandard. Wir haben den Zusammenhang zwischen Manschetten-gemessenen und invasiv-gemessenen Blutdruckwerten evaluiert. Die Blutdruckwerte[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 128.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.06.1984, 08:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 113.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.05.1984, 08:00, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Beam size and position measurement based on logarithm processing algorithm in HLS II
Creators: name: Cheng, Chaocai
name: Sun, Baogen
name: Yang, Yongliang
name: Zhou, Zeran
name: Lu, Ping
name: Wu, Fangfang
name: Wang, Jigang
name: Tang, Kai
name: Luo, Qing
name: Li, Hao
name: Zheng, Jiajun
name: Duan, Qingming
Publisher: name: arXiv
Year: 2015
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A logarithm processing algorithm to measure beam transverse size and position is proposed and preliminary experimental results in Hefei Light Source II (HLS II) are given. The algorithm is based on only 4 successive channels of 16 anode channels of multianode photomultiplier tube (MAPMT) R5900U-00-L16 which has typical rise time of 0.6 ns and effective area of 0.8x16 mm for a single anode channel. In the paper, we firstly elaborate the simulation results of the algorithm with and without channel inconsistency. Then we calibrate the channel inconsistency and verify the algorithm using general current signal processor Libera Photon in low-speed scheme. Finally we get turn-by-turn beam size and position and calculate the vertical tune in high-speed scheme. The experimental results show that measured values fit well with simulation results after channel differences are calibrated and the fractional part of the tune in vertical direction is 0.3628 which is very close to the nominal value 0.3621.
description: 6 pages, 11 figures, 7 equations
Mating pair stabilization mediates species specificity during bacterial conjugation
Creators: name: Low, Wen Wen
Publisher: name: Imperial College London
Year: 2022

description: Bacterial conjugation is a contact-dependent form of horizontal gene transfer where DNA is transferred in a unidirectional manner from a donor to recipient bacterium. It is also a key driver of the spread of antimicrobial resistance plasmids within clinically important pathogens. The intimate attachment of cells within a conjugating pair is crucial for efficient DNA transfer. However, the mechanism underlying the formation of tight mating junctions, which occurs through a process termed mating pair stabilization (MPS), is unclear. This work describes how variants of the plasmid-encoded outer membrane protein TraN interact with different receptors on recipient cells to mediate MPS. Using a reporter plasmid generated from the Klebsiella pneumoniae carbapenem resistance plasmid pKpQIL, mutations in the major outer membrane porin OmpK36 were found to reduce plasmid uptake in recipients. Meanwhile, substitution of traN on this plasmid with traN from two related plasmids, the Shigella flexneri resistance plasmid, R100-1 and the prototypical F plasmid, revealed that these TraN variants mediate dependency on recipient OmpW and OmpA respectively instead. Structural analysis showed that TraN from pKpQIL forms a complex with OmpK36 via the insertion of a β-hairpin structure into one of the subunits of the trimeric porin. Combining bioinformatic analysis and structural predictions using AlphaFold, four additional TraN variants were identified. All seven TraN variants could be classified into four groups based on their structural similarity and associated receptors: TraNα (OmpW), TraNβ (OmpK36), TraNγ (OmpA) and TraNδ (OmpF). Species specificity was also observed during MPS as not all homologues of a receptor are recognized by each TraN. This specificity was reflected in the real-world host distribution of conjugative IncF plasmids suggesting that MPS plays an influential role in shaping the host range of these plasmids. These findings provide a precedent for developing strategies that target MPS to mitigate resistance gene dissemination.
Sonnenfleckenzeichnung Nr. 192.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.08.1984, 08:00, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Using Open Data from Remote Sensing for assessment of Ecosystem Health with Jakub Zelený (People in Need)
Creators: name: , Kristýna
name: , Jakub
Publisher: name: Zenodo
Year: 2022
Subjects: oaw
openaccessweek

description: Presentation at the Open Access Week at the CZU in Prague for the lecture: Using Open Data from Remote Sensing for assessment of Ecosystem Health with Jakub Zelený (People in Need), 26 October 2022, 10:30 to 11:30. Link to the recording: https://youtu.be/R61o_XPs3ic
On the structure of learning and transfer in machines
Creators: name: Petangoda, Janith
Publisher: name: Imperial College London
Year: 2022

description: Machine Learning (ML) is often described as a process of learning about patterns and relationships. Structure is an example of the relationship between spaces of things; in this work, we provide a definition of learning in machines written as the process of learning unknown structure. This produces a unified view of ML that affords us concrete notions of spaces of tasks, and how they relate to chosen models. Using such a view, we define what it means to transfer between ML problems, and how to learn to transfer. Our definition embodies the notion that transfer is tightly coupled with biases, in that to transfer is to assume biases. Further, we define transfer in the same language of structure as we did vanilla learning; the key difference manifests as the structure that is learnt. This definition highlights differences between learning to transfer, and learning by transfer. We provide a framework, based on the theory of foliations that expresses our notions of transfer in the context of structure. We express popular methods of transfer in ML using our framework, and discuss how our framework informs us about the benefits of transfer. The primary goal of this thesis is to introduce the mathematical and philosophical frameworks by which learning and transfer in machines can be expressed and interpreted consistently in terms of structure.
Sonnenfleckenzeichnung Nr. 38.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.02.1984, 13:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 54.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.03.1984, 08:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Therapeutisches Drug Monitoring von Antiinfektiva in der Schwerbrandverletztenintensivmedizin
Creators: name: Horter, J.
name: Bliesener, B.
name: Ziegler, B.
name: Hirche, C.
name: Kneser, U.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Ein therapeutisches Drug Monitoring (TDM) ermöglicht die Bestimmung der Arzneimittelkonzentration in unterschiedlichen Körperflüssigkeiten und – unter Hinzuziehung klinischer und patientenspezifischer Parameter – die Simulation von Konzentrations-/Zeitprofilen.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 155.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.07.1984, 07:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Developmental vitamin D deficiency and schizophrenia: the role of animal models: Vitamin D deficiency and schizophrenia
Creators: name: Tarantino,
name: Schoenrock,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Schizophrenia is a debilitating neuropsychiatric disorder that affects 1% of the US population. Based on twin and genome-wide association studies, it is clear that both genetics and environmental factors increase the risk for developing schizophrenia. Moreover, there is evidence that conditions in utero, either alone or in concert with genetic factors, may alter neurodevelopment and lead to an increased risk for schizophrenia. There has been progress in identifying genetic loci and environmental exposures that increase risk, but there are still considerable gaps in our knowledge. Furthermore, very little is known about the specific neurodevelopmental mechanisms upon which genetics and the environment act to increase disposition to developing schizophrenia in adulthood. Vitamin D deficiency during the perinatal period has been hypothesized to increase risk for schizophrenia in humans. The developmental vitamin D (DVD) deficiency hypothesis of schizophrenia arises from the observation that disease risk is increased in individuals who are born in winter or spring, live further from the equator or live in urban vs. rural settings. These environments result in less exposure to sunlight, thereby reducing the initial steps in the production of vitamin D. Rodent models have been developed to characterize the behavioral and developmental effects of DVD deficiency. This review focuses on these animal models and discusses the current knowledge of the role of DVD deficiency in altering behavior and neurobiology relevant to schizophrenia.
title: Bronchoskopie bei Inhalationstraumen – Benefit oder Schaden?
Creators: name: Ziegler, B.
name: Hundeshagen, G.
name: Horter, J.
name: Bliesener, B.
name: Hirche, C.
name: Kneser, U.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Fiberoptische Bronchoskopie gilt als Goldstandard in der Diagnostik von Inhalationstraumen im Rahmen von Verbrennungsverletzungen. Hierfür steht der Abbreviated Injury Score (AIS) für Inhalationstraumen, der bronchoskopische Beobachtungen in vier Schweregrade kategorisiert, zu [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 183.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.07.1984, 07:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Cesta k Open Access s Janem Komárkem a Tomášem Kloučkem (FŽP ČZU)
Creators: name: , Kristýna
name: , Jan
name: , Tomáš
Publisher: name: Zenodo
Year: 2022
Subjects: oaw
openaccessweek

description: Prezentace v rámci Open Access Weeku na ČZU v Praze k přednášce: Cesta k Open Access s Janem Komárkem a Tomášem Kloučkem (FŽP ČZU), 25. 10. 2022 14:00 až 15:00. Odkaz na nahrávku: https://youtu.be/W4CRRJ-8IHk
Sonnenfleckenzeichnung Nr. 197.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.08.1984, 08:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Vorteile der Anwendung von Dexmedetomidin in der Weaningphase und Delirprophylaxe bei Verbrennungspatienten – Eine Anwendungsbeobachtung
Creators: name: Steinhauer, F.
name: Kisch, T.
name: Rautenbach, S.
name: Mailänder, P.
name: Stang, F.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Insbesondere bei schwerbrandverletzten Patienten kommt es nach häufig wochenlanger intensivmedizinischer Therapie und invasiver Beatmung mit zahlreichen Operationen zu einer prologierten Weaningphase mit gleichzeitig auftretendem Delir. Die verlängerte Weaningphase und die damit[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 23.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.01.1984, 09:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Data Reduction with the MIKE Spectrometer
Creators: name: Bernstein, Rebecca A.
name: Burles, Scott M.
name: Prochaska, J. Xavier
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: This manuscript describes the design, usage, and data-reduction pipeline developed for the Magellan Inamori Kyocera Echelle (MIKE) spectrometer used with the Magellan telescope at the Las Campanas Observatory. We summarize the basic characteristics of the instrument and discuss observational procedures recommended for calibrating the standard data products. We detail the design and implementation of an IDL based data-reduction pipeline for MIKE data (since generalized to other echelle spectrometers, e.g. Keck/HIRES, VLT/UVES). This includes novel techniques for flat-fielding, wavelength calibration, and the extraction of echelle spectroscopy. Sufficient detail is provided in this manuscript to enable inexperienced observers to understand the strengths and weaknesses of the instrument and software package and an assessment of the related systematics.
description: In press at PASP. Code is available at http://www.ucolick.org/~xavier/IDL/
Sonnenfleckenzeichnung Nr. 5.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.01.1984, 09:45, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Anwendung von Fibrogammin beim Schwerbrandverletzten
Creators: name: Rubenbauer, J.
name: Broer, P. N.
name: Ninkovic, M.
name: Falk, J.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Seit 2015 findet an der München Klinik Bogenhausen der Laborwert des Gerinnungsparameters „Faktor XIII“ besondere Bedeutung. Nachdem bei vornehmlich brandverletzten Patienten vermehrt Komplikationen in Folge von erhöhtem Blutverlust auftraten, wurden die Kontrolle[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 55.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.03.1984, 08:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 35.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.02.1984, 10:00, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Coarse-grained sensitivity for multiscale data assimilation
Creators: name: Sugiura, Nozomi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences

description: We show that the effective average action and its gradient are useful for solving multiscale data assimilation problems. We also present a procedure for numerically evaluating the gradient of the effective average action, and demonstrate that the variational problem for slow degrees of freedom can be solved properly using the "effective gradient."
description: 20 pages, 7 figures, revision 4
title: ITS KISS Brandverletzte Update
Creators: name: Storm, U.
name: Onallah, R.
name: Homann, H.-H.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Im Infektionsschutzgesetz ist die Surveillance von nosokomialen Infektionen gesetzlich vorgegeben. Die wichtigen Elemente sind die Bewertung der Daten und Evaluation zur Messung der Effektivität der umgesetzten Präventionsmaßnahmen. KISS ermöglicht den Kliniken seit 1997 die[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)