cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Epilobium tomentosum Vent., Descr. Pl. Nouv.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Myrtales
Onagraceae
Epilobium
Epilobium tomentosum

description: 26. Epilobium tomentosum Vent., Descr. Pl. Nouv.: tab. 90. 1802.
 Lectotypus (designated here): [IRAN]: Hort. Cels, Ventenat s.n. (G [G00406205]!; probable isolecto-: G-DC [G00654566]!).
 = Epilobium hirsutum L.
 Notes. – Two specimens of a single gathering have been located in Ventenat’s herbarium at G. It represents the plant cultivated in Cels’s garden. A collection in G-DC with the mention “h. Cels” may represents original material. We therefore prefer to designate here the lectotype on the unique collection extant in Ventenat’s herbarium.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 104, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
MOESM3 of Fhl1p protein, a positive transcription factor in Pichia pastoris, enhances the expression of recombinant proteins
Creators: name: Zheng, Xueyun
name: Zhang, Yimin
name: Zhang, Xinying
name: Li, Cheng
name: Liu, Xiaoxiao
name: Lin, Ying
name: Liang, Shuli
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3. The changed biological processes of the overexpression strain 4 pel/AF in comparison to 4 pel.
Spintronics and Quantum Dots for Quantum Computing and Quantum Communication
Creators: name: Burkard, Guido
name: Engel, Hans-Andreas
name: Loss, Daniel
Publisher: name: arXiv
Year: 2000
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Control over electron-spin states, such as coherent manipulation, filtering and measurement promises access to new technologies in conventional as well as in quantum computation and quantum communication. We review our proposal of using electron spins in quantum confined structures as qubits and discuss the requirements for implementing a quantum computer. We describe several realizations of one- and two-qubit gates and of the read-in and read-out tasks. We discuss recently proposed schemes for using a single quantum dot as spin-filter and spin-memory device. Considering electronic EPR pairs needed for quantum communication we show that their spin entanglement can be detected in mesoscopic transport measurements using metallic as well as superconducting leads attached to the dots.
description: Prepared for Fortschritte der Physik special issue, Experimental Proposals for Quantum Computation. 15 pages, 5 figures; typos corrected, references added
An effective clustering method based on data indeterminacy in neutrosophic set domain
Creators: name: Rashno, Elyas
name: Minaei-Bidgolia, Behrouz
name: Guo, Yanhui
Publisher: name: arXiv
Year: 2018
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In this work, a new clustering algorithm is proposed based on neutrosophic set (NS) theory. The main contribution is to use NS to handle boundary and outlier points as challenging points of clustering methods. In the first step, a new definition of data indeterminacy (indeterminacy set) is proposed in NS domain based on density properties of data. Lower indeterminacy is assigned to data points in dense regions and vice versa. In the second step, indeterminacy set is presented for a proposed cost function in NS domain by considering a set of main clusters and a noisy cluster. In the proposed cost function, two conditions based on distance from cluster centers and value of indeterminacy, are considered for each data point. In the third step, the proposed cost function is minimized by gradient descend methods. Data points are clustered based on their membership degrees. Outlier points are assigned to noise cluster; and boundary points are assigned to main clusters with almost same membership degrees. To show the effectiveness of the proposed method, three types of datasets including diamond, UCI and image datasets are used. Results demonstrate that the proposed cost function handles boundary and outlier points with more accurate membership degrees and outperforms existing state of the art clustering methods in all datasets.
description: Submitted to: Engineering Applications of Artificial Intelligence, Elsevier
Dynamical CP Violation and Flavour-Changing Processes
Creators: name: Branco, G. C.
name: Delepine, D.
name: Felipe, R. Gonzalez
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the phenomenological constraints on a model where, besides the standard model Higgs sector, there is an effective new strong interaction acting on the third generation of quarks and characterized by a $θ$-like term. This $θ$ term induces electroweak symmetry breaking and leads to dynamical spontaneous CP violation. We show that the constraints coming from K physics and the electric dipole moment of the neutron impose that the new physics scale should be of the order of 35 TeV. Contrary to naive expectations, the predictions of the model for B physics are very close to the standard model ones. The main differences appear in processes involving the up quarks such as $D^0-\bar{D}^0$ mixing and in the electric dipole moment of the neutron, which should be close to the experimental limit. Possible deviations from the standard model predictions for CP asymmetries in B decays are also considered.
description: LaTeX, 25 pages, 4 figures
beta-adrenergic receptor-mediated transactivation of EGFR decreases cardiomyocyte apoptosis through differential subcellular activation of ERK and Akt.pdf
Creators: name: Grisanti, Laurel A.
name: Talarico, Jennifer A.
name: Carter, Rhonda L.
name: Yu, Justine E.
name: Repas, Ashley A.
name: Radcliffe, Scott W.
name: Hoang-Ai Tang
name: Makarewich, Catherine A.
name: Houser, Steven R.
name: Tilley, Douglas G.
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: β-Adrenergic receptor (βAR)-mediated transactivation of epidermal growth factor receptor (EGFR) has been
shown to relay pro-survival effects via unknown mechanisms. We hypothesized that acute βAR-mediated
EGFR transactivation in the heart promotes differential subcellular activation of ERK1/2 and Akt, promoting
cell survival through modulation of apoptosis. C57BL/6 mice underwent acute i.p. injection with isoproterenol
(ISO)±AG 1478 (EGFR antagonist) to assess the impact of βAR-mediated EGFR transactivation on the phosphorylation
of ERK1/2 (P-ERK1/2) and Akt (P-Akt) in distinct cardiac subcellular fractions. Increased P-ERK1/2 and
P-Akt were observed in cytosolic, plasma membrane and nuclear fractions following ISO stimulation. Whereas
the P-ERK1/2 response was EGFR-sensitive in all fractions, the P-Akt response was EGFR-sensitive only in the
plasma membrane and nucleus, results confirmed in primary rat neonatal cardiomyocytes (RNCM). βARmediated
EGFR-transactivation also decreased apoptosis in serum-depleted RNCM, as measured via TUNEL as
well as caspase 3 activity/cleavage, which were sensitive to the inhibition of either ERK1/2 (PD184352) or Akt
(LY-294002) signaling. Caspase 3 activity/cleavage was also sensitive to the inhibition of transcription, which,
with an increase in nuclear P-ERK1/2 and P-Akt in response to ISO, suggested that βAR-mediated EGFR
transactivation may regulate apoptotic gene transcription. An Apoptosis PCR Array identified tnfsf10 (TRAIL) to
be altered by ISO in an EGFR-sensitive manner, results confirmed via RT-PCR and ELISA measurement of both
membrane-bound and soluble cardiomyocyte TRAIL levels. βAR-mediated EGFR transactivation induces differential
subcellular activation of ERK1/2 and Akt leading to increased cell survival through themodulation of caspase
3 activity and apoptotic gene expression in cardiomyocytes.
A numerical scheme for the quantile hedging problem
Creators: name: Bénézet, Cyril
name: Chassagneux, Jean-François
name: Reisinger, Christoph
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Finance (q-fin.CP)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Numerical Analysis (math.NA)
subject: FOS: Economics and business
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We consider the numerical approximation of the quantile hedging price in a non-linear market. In a Markovian framework, we propose a numerical method based on a Piecewise Constant Policy Timestepping (PCPT) scheme coupled with a monotone finite difference approximation. We prove the convergence of our algorithm combining BSDE arguments with the Barles & Jakobsen and Barles & Souganidis approaches for non-linear equations. In a numerical section, we illustrate the efficiency of our scheme by considering a financial example in a market with imperfections.
description: 47 pages, 6 figures
Eupatorium ayapana Vent., Jard. Malmaison
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Eupatorium
Eupatorium ayapana

description: 27. Eupatorium ayapana Vent., Jard. Malmaison 1: tab. 3. 1803.
 Lectotypus (designated here): [BRAZIL]: Hort. Malmaison, Ventenat s.n. (G [G00341565 right hand specimen]!; probable isolecto-: G-DC [G00495105]!).
 = Ayapana triplinervis (Vahl) R.M. King & H. Rob.
 Notes. – The only sheet in the Ventenat herbarium consists of two gatherings. The plant cultivated at Malmaison and a Michaux collection from Mauritius [G00341565 left hand specimen] where the plant had for long been cultivated. We designate here as the lectotype the specimen from Malmaison as it is the most complete material. A probable isolectotype exists in G-DC.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 104, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
Pd/Cu Site Interchange and Non-Fermi-Liquid Behavior in UCu_4Pd
Creators: name: Booth, C. H.
name: MacLaughlin, D. E.
name: Heffner, R. H.
name: Chau, R.
name: Maple, M. B
name: Kwei, G. H.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: X-ray-absorption fine-structure measurements of the local structure in UCu_4Pd are described which indicate a probable lattice-disorder origin for non-Fermi-liquid behavior in this material. Short Pd-Cu distances are observed, consistent with 24 +/- 3% of the Pd atoms occupying nominally Cu sites. A "Kondo disorder" model, based on the effect on the local Kondo temperature T_K of this interchange and some additional bond-length disorder, agrees quantitatively with previous experimental susceptibility data, and therefore also with specific heat and magnetic resonance experiments.
description: 4 pages, 3 PostScript figures, to be published in PRL
Additional file 1 of What is the relationship between health-related quality of life among scoliosis patients and their caregiver burden? A cross-sectional study in China
Creators: name: Shi, Zhao
name: Mao, Zhuxin
name: Xue, Shiwen
name: Chen, Gang
name: Li, Shunping
Publisher: name: figshare
Year: 2023
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Supplementary Material 1
Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.pdf
Creators: name: Sato, Priscila Y.
name: J. Kurt Chuprun
name: Grisanti, Laurel A.
name: Woodall, Meryl C.
name: Brown, Brett R.
name: Rajika Roy
name: Traynham, Christopher J.
name: Ibetti, Jessica
name: Lucchese, Anna M.
name: Ancai Yuan
name: Drostatos, Konstantinos
name: Tilley, Douglas G.
name: Erhe Gao
name: Koch, Walter J.
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Increased abundance of GRK2 [G protein–coupled receptor (GPCR) kinase 2] is associated with poor cardiac function in heart failure patients. In animal models, GRK2 contributes to the pathogenesis of heart failure after ischemia-reperfusion (IR) injury. In addition to its role in down-regulating activated GPCRs, GRK2 also localizes to mitochondria both basally and post-IR injury, where it regulates cellular metabolism. We previously showed that phosphorylation of GRK2 at Ser670 is essential for the translocation of GRK2 to the mitochondria of cardiomyocytes post-IR injury in vitro and that this localization promotes cell death. Here, we showed that mice with a S670A knock-in mutation in endogenous GRK2 showed reduced cardiomyocyte death and better cardiac function post-IR injury. Cultured GRK2-S670A knock-in cardiomyocytes subjected to IR in vitro showed enhanced glucose-mediated mitochondrial respiratory function that was partially due to maintenance of pyruvate dehydrogenase activity and improved glucose oxidation. Thus, we propose that mitochondrial GRK2 plays a detrimental role in cardiac glucose oxidation post-injury.
Characteristic Functionals of Dirichlet Measures
Creators: name: Schiavo, L. Dello
Publisher: name: arXiv
Year: 2018
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60E05 (Primary) 60G57, 62E10, 46F25, 33C65, 33C67 (Secondary)

description: We compute characteristic functionals of Dirichlet-Ferguson measures over a locally compact Polish space and prove continuous dependence of the random measure on the parameter measure. In finite dimension, we identify the dynamical symmetry algebra of the characteristic functional of the Dirichlet distribution with a simple Lie algebra of type $A$. We study the lattice determined by characteristic functionals of categorical Dirichlet posteriors, showing that it has a natural structure of weight Lie algebra module and providing a probabilistic interpretation. A partial generalization to the case of the Dirichlet-Ferguson measure is also obtained.
description: 31 pages, 3 figures
QCD Signatures of Narrow Graviton Resonances in Hadron Colliders
Creators: name: Bijnens, J.
name: Eerola, P.
name: Maul, M.
name: Mansson, A.
name: Sjostrand, T.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We show that the characteristic p_\perp spectrum yields valuable information for the test of models for the production of narrow graviton resonances in the TeV range at LHC. Furthermore, it is demonstrated that in those scenarios the parton showering formalism agrees with the prediction of NLO matrix element calculations.
description: 6 pages, 9 figures, LaTeX
Rapid exponential stabilization of a 1-D transmission wave equation with in-domain anti-damping
Creators: name: Hassine, Fathi
Publisher: name: arXiv
Year: 2018
Subjects: subject: Systems and Control (eess.SY)
subject: Optimization and Control (math.OC)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Mathematics
subject: 35A01, 35A02, 35M33, 93D20

description: We consider the problem of pointwise stabilization of a one-dimensional wave equation with an internal spatially varying anti-damping term. We design a feedback law based on the backstepping method and prove exponential stability of the closed-loop system with a desired decay rate.
description: 15 pages
Heracleum absinthifolium Vent., Choix Pl.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Apiales
Apiaceae
Heracleum
Heracleum absinthifolium

description: 28. Heracleum absinthifolium Vent., Choix Pl.: tab. 7. 1803.
 Ξ Zosima absinthifolia (Vent.) Link
 Lectotypus (designated here): [TURKEY]: Hort. Cels, Ventenat s.n. (G [G00341310]!) (Fig. 5).
 Notes. – When validating the name Heracleum absinthifolium, Ventenat referred to “Sphondylium orientale humulius, foliis absinthii”, a pre-linnean name coined by Joseph Pitton de Tournefort (1656-1708) in the herbaria of Vaillant and Jussieu. A specimen has been located in Herb. Vaillant and is here considered as original material [P00662760]. Further collections of Bruguière and Olivier from Turkey have been located in G-DC [G00477269]. The only collection f rom Cels’s garden in Ventenat’s herbarium is designated here as the lectotype. Recent revisions of the genus Zosima Hoffm. (Alava, 1987; Menemen & Jury, 2001) cited as type material a collection at G with the locality information taken from Ventenat; however no collection exists with this locality.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 104, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
Non-Equilibrium Production of Photons via π^0\to 2γin DCC's
Creators: name: Boyanovsky, D.
name: de Vega, H. J.
name: Holman, R.
name: Kumar, S. Prem
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study production of photons via the non-equilibrium relaxation of a Disoriented Chiral Condensate with the chiral order parameter having a large initial amplitude along the π^0 direction. Assuming the validity of the low energy coupling of the neutral pion to photons via the U_A(1) anomalous vertex, we find that for large initial amplitudes along the π^0 direction, photon production is enhanced by parametric amplification. These processes are non-perturbative with a large contribution during the non-equilibrium stages of the evolution and result in a distinct distribution of the produced photons and a polarization asymmetry. For initial amplitudes of the π^0 component of the order parameter between 200-400 MeV, corresponding to energy densities between 1-12 GeV/fm^3 we find a peak in the photon distribution at energies between \approx 300 -600 MeV. We also find polarization asymmetries typically between 5-10%. We discuss the potential experimental impact of these results as well as the problems associated with its detection.
description: 36 pages, 14 figures, uses revtex
A proof of the Shepp-Olkin entropy monotonicity conjecture
Creators: name: Hillion, Erwan
name: Johnson, Oliver
Publisher: name: arXiv
Year: 2018
Subjects: subject: Probability (math.PR)
subject: Information Theory (cs.IT)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: Consider tossing a collection of coins, each fair or biased towards heads, and take the distribution of the total number of heads that result. It is natural to conjecture that this distribution should be 'more random' when each coin is fairer. Indeed, Shepp and Olkin conjectured that the Shannon entropy of this distribution is monotonically increasing in this case. We resolve this conjecture, by proving that this intuition is correct. Our proof uses a construction which was previously developed by the authors to prove a related conjecture of Shepp and Olkin concerning concavity of entropy. We discuss whether this result can be generalized to $q$-Rényi and $q$-Tsallis entropies, for a range of values of $q$.
description: 16 pages
Morphology transitions in three-dimensional domain growth with Gaussian random fields
Creators: name: Koiller, Belita
name: Robbins, Mark O.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the morphology of magnetic domain growth in disordered three dimensional magnets. The disordered magnetic material is described within the random-field Ising model with a Gaussian distribution of local fields with width $Δ$. Growth is driven by a uniform applied magnetic field, whose value is kept equal to the critical value $H_c(Δ)$ for the onset of steady motion. Two growth regimes are clearly identified. For low $Δ$ the growing domain is compact, with a self-affine external interface. For large $Δ$ a self-similar percolation-like morphology is obtained. A multi-critical point at $(Δ_c$, $H_c(Δ_c))$ separates the two types of growth. We extract the critical exponents near $Δ_c$ using finite-size scaling of different morphological attributes of the external domain interface. We conjecture that the critical disorder width also corresponds to a maximum in $H_c(Δ)$.
description: 8 pages, 10 figures, submitted to Phys. Rev. B
MOESM6 of Fhl1p protein, a positive transcription factor in Pichia pastoris, enhances the expression of recombinant proteins
Creators: name: Zheng, Xueyun
name: Zhang, Yimin
name: Zhang, Xinying
name: Li, Cheng
name: Liu, Xiaoxiao
name: Lin, Ying
name: Liang, Shuli
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 6. Primers used for the construction of engineered strains and the verification of RNA-Seq data by RT-PCR.
Ab initio vibrational free energies including anharmonicity for multicomponent alloys
Creators: name: Grabowski, Blazej
name: Ikeda, Yuji
name: Körmann, Fritz
name: Freysoldt, Christoph
name: Duff, Andrew Ian
name: Shapeev, Alexander
name: Neugebauer, Jörg
Publisher: name: arXiv
Year: 2019
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A density-functional-theory based approach to efficiently compute numerically exact vibrational free energies - including anharmonicity - for chemically complex multicomponent alloys is developed. It is based on a combination of thermodynamic integration and a machine-learning potential. We demonstrate the performance of the approach by computing the anharmonic free energy of the prototypical five-component VNbMoTaW refractory high entropy alloy.
pepducin-mediated cardioprotection via beta-arrestin-biased beta2-adrenergic receptor-specific signaling.pdf
Creators: name: Grisanti, Laurel A.
name: Thomas, Toby P.
name: Carter, Rhonda L.
name: Lucia, Claudio De
name: Erhe Gao
name: Koch, Walter J.
name: Benovic, Jeffrey L.
name: Tilley, Douglas G.
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces
further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes
survival signaling responses in vitro; thus, we hypothesize that this pathway can mitigate cardiomyocyte death
at the time of reperfusion to better preserve function. However, a lack of efficacious βarr-biased orthosteric
small molecules has prevented investigation into whether this pathway relays protection against ischemic injury
in vivo. We recently demonstrated that the pepducin ICL1-9, a small lipidated peptide fragment designed from
the first intracellular loop of β2AR, allosterically engaged pro-survival signaling cascades in a βarr-dependent
manner in vitro. Thus, in this study we tested whether ICL1-9 relays cardioprotection against
ischemia/reperfusion (I/R)-induced injury in vivo.
Methods: Wild-type (WT) C57BL/6, β2AR knockout (KO), βarr1KO and βarr2KO mice received
intracardiac injections of either ICL1-9 or a scrambled control pepducin (Scr) at the time of ischemia (30 min)
followed by reperfusion for either 24 h, to assess infarct size and cardiomyocyte death, or 4 weeks, to monitor
the impact of ICL1-9 on long-term cardiac structure and function. Neonatal rat ventricular myocytes (NRVM)
were used to assess the impact of ICL1-9 versus Scr pepducin on cardiomyocyte survival and mitochondrial
superoxide formation in response to either serum deprivation or hypoxia/reoxygenation (H/R) in vitro and to
investigate the associated mechanism(s).
Results: Intramyocardial injection of ICL1-9 at the time of I/R reduced infarct size, cardiomyocyte death and
improved cardiac function in a β2AR- and βarr-dependent manner, which led to improved contractile function
early and less fibrotic remodeling over time. Mechanistically, ICL1-9 attenuated mitochondrial superoxide
production and promoted cardiomyocyte survival in a RhoA/ROCK-dependent manner. RhoA activation could
be detected in cardiomyocytes and whole heart up to 24 h post-treatment, demonstrating the stability of
ICL1-9 effects on βarr-dependent β2AR signaling.
Conclusion: Pepducin-based allosteric modulation of βarr-dependent β2AR signaling represents a novel
therapeutic approach to reduce reperfusion-induced cardiac injury and relay long-term cardiac remodeling
benefits.
Numerical studies of the phase diagram of layered type II superconductors in a magnetic field
Creators: name: Kienappel, A. K.
name: Moore, M. A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report on simulations of layered superconductors using the Lawrence-Doniach model in the framework of the lowest Landau level approximation. We find a first order phase transition with a $B(T)$ dependence which agrees very well with the experimental ``melting'' line in YBaCuO. The transition is not associated with vortex lattice melting, but separates two vortex liquid states characterised by different degrees of short-range crystalline order and different length scales of correlations between vortices in different layers. The transition line ends at a critical end-point at low fields. We find the magnetization discontinuity and the location of the lower critical magnetic field to be in good agreement with experiments in YBaCuO. Length scales of order parameter correlations parallel and perpendicular to the magnetic field increase exponentially as 1/T at low temperatures. The dominant relaxation time scales grow roughly exponentially with these correlation lengths. We find that the first order phase transition persists in the presence of weak random point disorder but can be suppressed entirely by strong disorder. No vortex glass or Bragg glass state is found in the presence of disorder. The consistency of our numerical results with various experimental features in YBaCuO, including the dependence on anisotropy, and the temperature dependence of the structure factor at the Bragg peaks in neutron scattering experiments is demonstrated.
description: 25 pages (revtex), 19 figures included, submitted to PRB
Circular Motion and Energy Extraction in a Rotating Black Hole
Creators: name: Shahzadi, M.
name: Yousaf, Z.
name: Khan, Saeed Ullah
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: This paper explores the circular geodesics of neutral test particles on an equatorial plane around a rotating black hole. After using equations of motion of scalar-tensor-vector gravity with the circular geodesics of null-like particles, we find the equation of photon orbit. With the help of an effective potential form, we have examined the stable regimes of photons orbits. The Lyapunov exponent, as well as the effective force acting on photons, is also investigated. We examine the energy extraction from a black hole via Penrose process. Furthermore, we discuss the negative energy state and the efficiency of energy extraction. We have made compare our results with that obtained for some well known black holes models. We concluded that the efficiency of the energy extraction decreases with the increase of dimensionless parameter of theory and increases as spin parameter increases.
description: 24 pages, 9 figures
Hypericum dolabriforme Vent., Descr. Pl. Nouv.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Hypericaceae
Hypericum
Hypericum dolabriforme

description: 29. Hypericum dolabriforme Vent., Descr. Pl. Nouv.: tab. 45. 1801.
 Lectotypus (designated by Robson, 1996: 123): U NITED STATES. Kentucky: Michaux s.n. (G [G00341526]!; isolecto-: P [P01901389, P02442087, P02442088, P02442089, P02442090]!, P-JU n° 11841 [P00667214]!, P-MICH [P00667207, P00667217]!).
 Notes. – Hypericum dolabriforme is endemic to the southeastern regions of the United States (from southern Indiana to northwestern Georgia) (Robson, 1996). Only a single specimen exists in Ventenat’s herbarium, i.e. the Michaux collection from Kentucky. Michaux (1803: 81) validated the name H. procumbens Michx. [nom. illeg.] [non Desf. ex Willd.] based on the same material. Robson (1996: 123) implicitly lectotypied Ventenat’s name by referring to the unique specimen at G. A collection of this species given by Ventenat to Jussieu from Cels’s garden in 1803 is here considered as original material (P-JU n° 11832 [P00667211]).
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 104, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic beta-adrenergic receptor stimulation.pdf
Creators: name: Grisanti, Laurel A.
name: Repas, Ashley A.
name: Talarico, Jennifer A.
name: Gold, Jessica I.
name: Carter, Rhonda L.
name: Koch, Walter J.
name: Tilley, Douglas G.
Publisher: name: Health Research Alliance
Year: 2019
Subjects: subject: 110201 Cardiology (incl. Cardiovascular Diseases)
subject: FOS: Clinical medicine

description: Chronic stimulation
of -adrenergic receptors ( AR) can promote survival signaling
via transactivation of epidermal growth factor receptor (EGFR)
but ultimately alters cardiac structure and contractility over time, in
part via enhanced cytokine signaling. We hypothesized that chronic
catecholamine signaling will have a temporal impact on cardiac
transcript expression in vivo, in particular cytokines, and that EGFR
transactivation plays a role in this process. C57BL/6 mice underwent
infusion with vehicle or isoproterenol (Iso) gefitinib (Gef) for 1 or
2 wk. Cardiac contractility decreased following 2 wk of Iso treatment,
while cardiac hypertrophy, fibrosis, and apoptosis were enhanced at
both timepoints. Inclusion of Gef preserved contractility, blocked
Iso-induced apoptosis, and prevented hypertrophy at the 2-wk timepoint,
but caused fibrosis on its own. RNAseq analysis revealed
hundreds of cardiac transcripts altered by Iso at each timepoint with
subsequent RT-quantitative PCR validation confirming distinct temporal
patterns of transcript regulation, including those involved in
cardiac remodeling and survival signaling, as well as numerous
cytokines. Although Gef infusion alone did not significantly alter
cytokine expression, it abrogated the Iso-mediated changes in a
majority of the AR-sensitive cytokines, including CCL2 and TNF- .
Additionally, the impact of AR-dependent EGFR transactivation on
the acute regulation of cytokine transcript expression was assessed in
isolated cardiomyocytes and in cardiac fibroblasts, where the majority
of Iso-dependent, and EGFR-sensitive, changes in cytokines occurred.
Overall, coincident with changes in cardiac structure and contractility,
 AR stimulation dynamically alters cardiac transcript expression over
time, including numerous cytokines that are regulated via EGFRdependent
signaling.
Solar radius and luminosity variations induced by the internal dynamo magnetic fields
Creators: name: Spada, F.
name: Arlt, R.
name: Kueker, M.
name: Sofia, S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Although the occurrence of solar irradiance variations induced by magnetic surface features (e.g., sunspots, faculae, magnetic network) is generally accepted, the existence of intrinsic luminosity changes due to the internal magnetic fields is still controversial. This additional contribution is expected to be accompanied by radius variations, and to be potentially significant for the climate of the Earth. We aim to constrain theoretically the radius and luminosity variations of the Sun that are due to the effect of the variable magnetic fields in its interior associated with the dynamo cycle. We have extended a one-dimensional stellar evolution code to include several effects of the magnetic fields on the interior structure. We investigate different magnetic configurations, based on both observational constraints and on the output of state-of-the-art mean field dynamo models. We explore both step-like and simply periodic time dependences of the magnetic field peak strength. We find that the luminosity and radius variations are in anti-phase and in phase, respectively, with the magnetic field strength. For peak magnetic field strengths of the order of tens of kilogauss, luminosity variations ranging between 10^{-6} and 10^{-3} (in modulus) and radius variations between 10^{-6} and 10^{-5} are obtained. Modest but significant radius variations (up to 10^{-5} in relative terms) are obtained for magnetic fields of realistic strength and geometry, providing a potentially observable signature of the intrinsic variations. Establishing their existence in addition to the accepted surface effects would have very important implications for the understanding of solar-induced long-term trends on climate.
description: 18 pages, 7 figures; accepted for publication in Astronomische Nachrichten
Auswirkung und Spätfolgen erwachsener Kinder alkoholabhängiger Eltern: Ein Handlungsfeld der Sozialen Arbeit
Creators: name: Müller, Kim
name: Pesenti, Jela
Publisher: name: Zenodo
Year: 2019

description: Die vorliegende Bachelor-Arbeit setzt sich mit Personen auseinander, die in der Kindheit eine Alkoholabhängigkeit bei den Eltern erlebt haben. Das Aufwachsen in einem Elternhaus mit einer Alkoholabhängigkeit kann weitreichende Auswirkungen und Spätfolgen im erwachsenen Leben für betroffene Kinder haben. Problematisch dabei ist, dass noch immer zu wenig Fokus auf diese Kinder gelegt wird, da bei einer Alkoholabhängigkeit, ganz im Gegensatz zu illegalen Drogen, weniger schnell reagiert wird. Dies hat sicher auch mit der gesellschaftlichen Akzeptanz von Alkohol zu tun. Sozialarbeitende kommen in ihrer Praxis häufig, wenn auch oft unbewusst, mit Personen mit einer solchen Vergangenheit in Berührung. Es ist daher wichtig, dass sie für dieses Thema sensibilisiert werden, damit sie klientengerecht reagieren können. Dabei ist die Wahl geeigneter Methoden und Interventionen zentral. Dies kann gewährleistet werden, indem das ganze System der betroffenen Person miteinbezogen und ressourcenorientiert agiert wird. Welche Methoden, Ansätze und Interventionen das professionelle Handeln bei erwachsenen Kindern alkoholabhängiger Eltern unterstützen können, wurde anhand der Allgemein normativen Handlungstheorie (ANHT) schrittweise aufgezeigt. Die Leserschaft erlangt durch diese Bachelor-Arbeit Faktenwissen, um für das wichtige Thema sensibilisiert zu werden und bekommt eine Vorstellung davon, wie die Allgemein normative Handlungstheorie angewendet werden kann.
description: + Code Diss LU: hslusa basa 2019 + Fussnote: Bachelorarbeit, Hochschule Luzern - Soziale Arbeit, Ausbildungsgang Sozialarbeit, 2019 + NL-Code: NLLUHSA201909
MOESM3 of Targeting glycosylation of PD-1 to enhance CAR-T cell cytotoxicity
Creators: name: Shi, Xiaojuan
name: Zhang, Daiqun
name: Li, Feng
name: Zhang, Zhen
name: Wang, Shumin
name: Xuan, Yujing
name: Ping, Yu
name: Zhang, Yi
Publisher: name: figshare
Year: 2019
Subjects: Biochemistry
Space Science
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Additional file 3: Table S1. Antibodies and materials list.
Role of $σR^{2}+γR_{μν}T^{μν}$ Model on Anisotropic Polytropes
Creators: name: Sharif, M.
name: Waseem, Arfa
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This paper analyzes the anisotropic stellar evolution governed by a polytropic equation of state in the framework of $f(R,T,Q)$ gravity, where $Q=R_{ab}T^{ab}$. We construct the field equations, hydrostatic equilibrium equation and trace equation to obtain their solutions numerically under the influence of $σR^{2}+γQ$ gravity model, where $σ$ and $γ$ are arbitrary constants. We examine the dependence of various physical characteristics such as radial/tangential pressure, energy density, anisotropic factor, total mass and surface redshift for specific values of the model parameters. The physical acceptability of the considered model is discussed by verifying the validity of energy conditions, causality condition, and adiabatic index. We also study the effects arising due to the strong non-minimal matter-curvature coupling on anisotropic polytropes. It is found that the polytropic stars are stable and their maximum mass point lies within the required observational Chandrasekhar limit.
description: 27 pages, 8 figures, to appear in IJMPD
Landau equations and asymptotic operation
Creators: name: Tkachov, Fyodor V.
Publisher: name: arXiv
Year: 1997
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The pinched/non-pinched classification of intersections of causal singularities of propagators in Minkowski space is reconsidered in the context of the theory of asymptotic operation as a first step towards extension of the latter to non-Euclidean asymptotic regimes. A highly visual distribution-theoretic technique of singular wave fronts is tailored to the needs of the theory of Feynman diagrams. Besides a simple derivation of the usual Landau equations in the case of the conventional singularities, the technique naturally extends to other types of singularities e.g. due to linear denominators in non-covariant gauges etc. As another application, the results of Euclidean asymptotic operation are extended to a class of quasi-Euclidean asymptotic regimes in Minkowski space.
description: 15p PS (GSview), IJMP-A (accepted)
Illicium parviflorum Michx. ex Vent., Tabl. Règn. Vég.
Creators: name: Callmander, Martin W.
name: Durbin, Olivier D.
name: Lack, Hans-Walter
name: Bungener, Patrick
name: Martin, Pascal
name: Gautier, Laurent
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Austrobaileyales
Schisandraceae
Illicium
Illicium parviflorum

description: 30. Illicium parviflorum Michx. ex Vent., Tabl. Règn. Vég. 3: 71. 1799 [cited in Descr. Pl. Nouv.: tab. 22. 1801].
 Lectotypus (designated here): UNITED STATES. Florida: Lake George, Michaux s.n. (G [G00341506]!; isolecto-: P [P01656597 upper specimen]!, P-MICH [P00667213]!).
 Notes. – Lin (2000: 177) in his revision of the genus cited the type of the name of this species as: “ U.S. Lake George, details unkown”. This cannot be accepted as an implicit lectotypification. Two specimens exist at G: the cultivated specimen from Cels’s garden [G00341505] and the collection from Michaux. The latter is designated as the lectotype as it is more complete and two isolectotypes have been located in the P and in P-MICH herbaria respectively.
A specimen annotated in Ventenat’s hand “ Illicium parviflorum H. Cels t. 22” and in D. F. K. v. Schlechtendal’s hand “Ventenat. W [illdenow]” [B-W 10382-01 0] is also available for interpretation of this name.
description: Published as part of Callmander, Martin W., Durbin, Olivier D., Lack, Hans-Walter, Bungener, Patrick, Martin, Pascal & Gautier, Laurent, 2017, Etienne-Pierre Ventenat (1757 - 1808) and the gardens of Cels and Empress Joséphine, pp. 87-132 in Candollea 72 (1) on page 105, DOI: 10.15553/c2017v721a8, http://zenodo.org/record/5721919
Force, charge, and conductance of an ideal metallic nanowire
Creators: name: Kassubek, F.
name: Stafford, C. A.
name: Grabert, Hermann
Publisher: name: arXiv
Year: 1998
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The conducting and mechanical properties of a metallic nanowire formed at the junction between two macroscopic metallic electrodes are investigated. Both two- and three-dimensional wires with a W(ide)-N(arrow)-W(ide) geometry are modelled in the free-electron approximation with hard-wall boundary conditions. Tunneling and quantum-size effects are treated exactly using the scattering matrix formalism. Oscillations of order E_F/lambda_F in the tensile force are found when the wire is stretched to the breaking point, which are synchronized with quantized jumps in the conductance. The force and conductance are shown to be essentially independent of the width of the wide sections (electrodes). The exact results are compared with an adiabatic approximation; the later is found to overestimate the effects of tunneling, but still gives qualitatively reasonable results for nanowires of length L>>lambda_F, even for this abrupt geometry. In addition to the force and conductance, the net charge of the nanowire is calculated and the effects of screening are included within linear response theory. Mesoscopic charge fluctuations of order e are predicted which are strongly correlated with the mesoscopic force fluctuations. The local density of states at the Fermi energy exhibits nontrivial behavior which is correlated with fine structure in the force and conductance, showing the importance of treating the whole wire as a mesoscopic system rather than treating only the narrow part.
description: 23 pages, 8 figures
Majorana Bound States in Double Nanowires with Reduced Zeeman Thresholds due to Supercurrents
Creators: name: Dmytruk, Olesia
name: Thakurathi, Manisha
name: Loss, Daniel
name: Klinovaja, Jelena
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the topological phase diagram of a setup composed of two nanowires with strong Rashba spin-orbit interaction subjected to an external magnetic field and brought into the proximity to a bulk $s$-wave superconductor in the presence of a supercurrent flowing through it. The supercurrent reduces the critical values of the Zeeman energy and crossed Andreev superconducting pairing required to reach the topological phase characterized by the presence of one Majorana bound state localized at each system end. We demonstrate that, even in the regime of the crossed Andreev pairing being smaller than the direct proximity pairing, a relatively weak magnetic field drives the system into the topological phase due to the presence of the supercurrent.
description: 10 pages, 7 figures
Extended calculations of energy levels and transition rates of Nd II-IV ions for application to neutron star mergers
Creators: name: Gaigalas, Gediminas
name: Kato, Daiji
name: Rynkun, Pavel
name: Radziute, Laima
name: Tanaka, Masaomi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Coalescence of binary neutron star give rise to electromagnetic emission, kilonova, powered by radioactive decays of r-process nuclei. Observations of kilonova associated with GW170817 provided unique opportunity to study the heavy element synthesis in the Universe. However, atomic data of r-process elements to decipher the light curves and spectral features of kilonova are not fully constructed yet. In this paper, we perform extended atomic calculations of neodymium (Nd, Z=60) to study the impact of accuracies in atomic calculations to the astrophysical opacities. By employing multiconfiguration Dirac-Hartree-Fock and relativistic configuration interaction methods, we calculate energy levels and transition data of electric dipole transitions for Nd II, Nd III, and Nd IV ions. Compared with previous calculations, our new results provide better agreement with the experimental data. The accuracy of energy levels was achieved in the present work 10 %, 3 % and 11 % for Nd II, Nd III and Nd IV, respectively, comparing with the NIST database. We confirm that the overall properties of the opacity are not significantly affected by the accuracies of the atomic calculations. The impact to the Planck mean opacity is up to a factor of 1.5, which affects the timescale of kilonova at most 20 %. However, we find that the wavelength dependent features in the opacity are affected by the accuracies of the calculations. We emphasize that accurate atomic calculations, in particular for low-lying energy levels, are important to provide predictions of kilonova light curves and spectra.
description: 24 pages, 9 figures, The Astrophysical Journal Supplement Series, in press
Mesons on a transverse lattice
Creators: name: Dalley, S.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The meson eigenstates of the light-cone Hamiltonian in a coarse transverse lattice gauge theory are investigated. Building upon previous work in pure gauge theory, the Hamiltonian and its Fock space are expanded in powers of dynamical fields. In the leading approximation, the couplings appearing in the Hamiltonian are renormalised by demanding restoration of space-time symmetries broken by the cut-off. Additional requirements from chiral symmetry are discussed and difficulties in imposing them from first principles in the leading approximation are noted. A phenomenological calculation is then performed, in which chiral symmetry in spontaneously broken form is modelled by imposing the physical pion-rho mass splitting as a constraint. The light-cone wavefunctions of the resulting Hamiltonian are used to compute decay constants, form factors and quark momentum and spin distributions for the pion and rho mesons. Extensions beyond leading order, and the implications for first principles calculations, are briefly discussed.
description: 31 pages, 7 figures