cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Global franchising: Current Status and Future Challenges
Creators: name: Hoffman, Richard C.
name: Preble, John F.
Publisher: name: Maryland Shared Open Access Repository
Year: 2004
Subjects: Franchising
International Markets
Global Growth
Services
Future Trends

description: About a decade ago positive predictions were made regarding the international growth of franchising. This study was undertaken to examine the actual growth and development of franchising globally during the nineties. Using survey and archival data findings regarding the state of franchising in 40 countries are presented. Franchising has met or exceeded the growth expectations, generating an average of $3.7 billion in annual sales in the nations investigated. However, considerable regional differences in franchising activities do exist. The business sectors experiencing the most franchising growth are retail and restaurants. Franchising firms tend to export their business formats to neighboring countries or to countries with similar cultural characteristics. Operational concerns regarding legal and social issues across borders are also examined. Implications for practice and research are discussed.
Synthesis of new morpholine containing 3-amido-9-ethylcarbazole derivative and studies on its biophysical interactions with calf thymus DNA/HSA
Creators: name: Kıpçak, Fulya
name: Tugba Taskın Tok
name: Duyar, Halil
name: Seferoğlu, Zeynel
name: Gökoğlu, Elmas
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: In this work, we presented the synthesis and investigation of binding properties of the new morpholine containing 3-amido-9-ethylcarbazole derivative (CMR) to calf thymus DNA (ctDNA) and human serum albumin (HSA) by fluorescence spectroscopy, UV absorption spectroscopy and molecular docking method. A decrease in Stern–Volmer constants was obtained with increase in temperature; it shows that static quenching mechanism leads to formation of new CMR-DNA/HSA complexes, which have hydrophobic interaction as the predominant role in the binding modes. Also, binding properties of DNA were investigated with competition assays on two probes (EB and H33258) by absorption, ionic strength and iodide ion quenching methods. The results suggested that CMR entered into the minor groove binding on the A-T region of DNA. The spectral data further confirmed by molecular docking which elicited that CMR complexes have similar interaction and conformation trends to each target, DNA and HSA. The experimental and computational results show that CMR has been classified as a promising molecule in drug designing of other carbazole derivatives. Communicated by Ramaswamy H. Sarma
The Influence of the Magnetic Field on the Properties of Neutron Star Matter
Creators: name: Chen, W.
name: Zhang, P. Q.
name: Liu, L. G.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In the mean field approximation of the relativistic $σ$-$ω$-$ρ$ model, the magnetic fields are incorporated, and its influence on the properties of n-p-e neutron star matter are studied. When the strength of the magnetic field is weaker than $\sim 10^{18}$G, the particle fractions and chemical potentials, matter energy density and pressure hardly change with the magnetic field; when the strength of the magnetic field is stronger than $\sim 10^{20}$G, the above quantities change with the magnetic field evidently. Furthermore, the pressure is studied in both thermodynamics and hydrodynamics. The difference between these two ways exits in the high density region, that is, the thermal self-consistency may not be satisfied in this region if the magnetic field is considered.
description: 7 pages, 4 figures, "Non-Perturbative Quantum Field Theory: Lattice and Beyond", Guangzhou, China
Kiliwa Generation Gap; Desert Fruits; The Land; Traditions (I)
Creators: name: Espinoza, Braulio
name: Mixco, Mauricio J.
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2021
Subjects: subject: klb

description: See Kiliwa Texts: "When I have Donned My Crest of Stars" (University of Utah Press, 1983), pp. 174, 185, 147, and 160 for transcription, segmentation, glossing, and translation of these stories, respectively.
Robust Model Predictive Longitudinal Position Tracking Control for an Autonomous Vehicle Based on Multiple Models
Creators: name: Kempf, André
name: Herrmann-Wicklmayr, Markus
name: Müller, Steffen
Publisher: name: arXiv
Year: 2020
Subjects: subject: Systems and Control (eess.SY)
subject: Robotics (cs.RO)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: The aim of this work is to control the longitudinal position of an autonomous vehicle with an internal combustion engine. The powertrain has an inherent dead-time characteristic and constraints on physical states apply since the vehicle is neither able to accelerate arbitrarily strong, nor to drive arbitrarily fast. A model predictive controller (MPC) is able to cope with both of the aforementioned system properties. MPC heavily relies on a model and therefore a strategy on how to obtain multiple linear state space prediction models of the nonlinear system via input/output data system identification from acceleration data is given. The models are identified in different regions of the vehicle dynamics in order to obtain more accurate predictions. The still remaining plant-model mismatch can be expressed as an additive disturbance which can be handled through robust control theory. Therefore modifications to the models for applying robust MPC tracking control theory are described. Then a controller which guarantees robust constraint satisfaction and recursive feasibility is designed. As a next step, modifications to apply the controller on multiple models are discussed. In this context, a model switching strategy is provided and theoretical and computational limitations are pointed out. Lastly, simulation results are presented and discussed, including computational load when switching between systems.
description: Accepted for 2020 IEEE Symposium Series on Computational Intelligence (IEEE SSCI)
Analyzing organophosphate pesticide-serum albumin binding interaction: A combined STD NMR and molecular docking study
Creators: name: Dahiya, Vandana
name: Bibin G. Anand
name: Karunakar Kar
name: Samanwita Pal
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine

description: In Vitro analysis of the interaction of organophosphate pesticides (OP) with bovine serum albumin (BSA) is crucial to understand their potential effects at the molecular level. In this context, we have employed Saturation Transfer Difference (STD) NMR experiments in conjunction with molecular docking studies to unravel the binding interaction of the OP chlorpyrifos (CPF), diazinon (DZN) and parathion (PA) in solution. The relative STD (%) suggested the detailed epitope mapping of these OP with BSA while the concentration-dependent STD NMR studies were performed to obtain the complex dissociation constant (KD) of the OP-BSA complexes; KD=1.81 × 10−4 M, 1.30 × 10−3 M and 1.11 × 10−3 M for CPF, DZN and PA were extracted respectively. Similar binding modes were identified for all the three OP using STD site-marker experiment. ITC experiments were performed as a complementary method that revealed a high binding affinity of OP-BSA complexes through non-covalent interaction. Molecular docking confirmed the possible interacting chemical groups of OP-BSA complexes. These significant results furnish valuable information about the toxicity risk of OP to proteins.
Johnius coitor
Creators: name: Hanafi, Norhafiz
name: Chen, Meng-Hsien
name: Chang, Chih-Wei
name: Chao, Ning Labbish
name: Seah, Ying Giat
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Perciformes
Sciaenidae
Johnius
Johnius coitor

description: Johnius coitor (Hamilton, 1822)
(Common name: Coitor croaker)
(Fig. 9, Table 6)
Bola coitor Hamilton, 1822: 75 (type locality: Ganges River as far as Kanpur and Jumna River at Angra and at Visakhapatum, India. No types known.
Johnius coitor (Hamilton, 1822): Sasaki, 2000: 621; Sasaki, 2001: 3144; Mohamad Faisal, 2009: 98.
Material examined. Non-types: NMMB-P37096 (3, 109.25 to 136.62 mm SL), Sibu, Sarawak, Malaysia, 12 March 2017; NMMB-P33374 (121.72 mm SL), Pasar Tamu Sri Aman, Sarawak, Malaysia, 19 November 2019.
Diagnosis. A species of Johnius with the following combination of characters: snout steep, obtusely pointed; mouth small, inferior; small eye, 12 to 16% of HL; gill rakers moderately long, slender, about 1/2 to 2/3 length of gill filaments at angle of arch, 9 to 11 on lower limb of first gill arch; second anal spine length long, stiff, about 35 to 40% of HL; and scales moderately small, 7 to 9 scale rows above lateral line.
Distribution. Eastern Indian Ocean, western Pacific; Bay of Bengal (India and Bangladesh) and to eastern Australia.
Remarks. Johnius coitor is rare, endemic species and only distributed in the East Malaysia waters, concisely at the Sibu site collection. In previous, Sasaki (2001) has mentioned the species distribution recorded in the Borneo and Malay Peninsula, but no types are known. Thus, this study gives the first clear baseline information based on voucher specimen, genetic information and morphological measurement in detailed. In addition, it also available collected at one site at the Sarawak states, which based on our observation collected at freshwater river which caught in the ~ 120 km upstream at Rajang River. This is might due to this species much prefer riverine ecological factor such as sandy and muddy habitat with the highly freshwater intrusion for their life preference. However, this study needs to provide in detail with the environmental and biological evidence as supporting data.
description: Published as part of Hanafi, Norhafiz, Chen, Meng-Hsien, Chang, Chih-Wei, Chao, Ning Labbish & Seah, Ying Giat, 2024, Taxonomic review of the genus Johnius (Perciformes: Sciaenidae) from East Malaysian waters, with comments on newly recorded Johnius species, pp. 85-117 in Zootaxa 5550 (1) on page 100, DOI: 10.11646/zootaxa.5550.1.11, http://zenodo.org/record/14388193
Compound basis arising from the basic $A^{(1)}_{1}$-module
Creators: name: Aokage, Kazuya
name: Mizukawa, Hiroshi
name: Yamada, Hiro-Fumi
Publisher: name: arXiv
Year: 2008
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 17B67

description: A new basis for the polynomial ring of infinitely many variables is constructed which consists of products of Schur functions and Q-functions. The transition matrix from the natural Schur function basis is investigated.
description: 12 pages
Petri, Heinrich: Divergenzen in der Mariologie - zur ökumenischen Diskussion um die Mutter Jesu
Creators: name: Vo.
Publisher: name: Ökumenische Rundschau
Year: 2025

description: Ökumenische Rundschau, Bd. 38 Nr. 3 (1989): Ökumenische Rundschau, Band 38, Heft 3
Gravitational waves from a holographic phase transition
Creators: name: Ares, Fëanor Reuben
name: Hindmarsh, Mark
name: Hoyos, Carlos
name: Jokela, Niko
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate first order phase transitions in a holographic setting of five-dimensional Einstein gravity coupled to a scalar field, constructing phase diagrams of the dual field theory at finite temperature. We scan over the two-dimensional parameter space of a simple bottom-up model and map out important quantities for the phase transition: the region where first order phase transitions take place; the latent heat, the transition strength parameter $α$, and the stiffness. We find that $α$ is generically in the range 0.1 to 0.3, and is strongly correlated with the stiffness (the square of the sound speed in a barotropic fluid). Using the LISA Cosmology Working Group gravitational wave power spectrum model corrected for kinetic energy suppression at large $α$ and non-conformal stiffness, we outline the observational prospects at the future space-based detectors LISA and TianQin. A TeV-scale hidden sector with a phase transition described by the model could be observable at both detectors.
description: 36 pages, 17 figures
On Transverse-Momentum Dependent Light-Cone Wave Functions of Light Mesons
Creators: name: Ma, J. P.
name: Wang, Q.
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Transverse-momentum dependent (TMD) light-cone wave functions of a light meson are important ingredients in the TMD QCD factorization of exclusive processes. This factorization allows one conveniently resum Sudakov logarithms appearing in collinear factorization. The TMD light-cone wave functions are not simply related to the standard light-cone wave functions in collinear factorization by integrating them over the transverse momentum. We explore relations between TMD light-cone wave functions and those in the collinear factorization. Two factorized relations can be found. One is helpful for constructing models for TMD light-cone wave functions, and the other can be used for resummation. These relations will be useful to establish a link between two types of factorization.
description: add more discussions and references
Plasma frequency in doped highly mismatched alloys
Creators: name: Allami, Hassan
name: Krich, Jacob J.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Highly mismatched alloys (HMAs) have band structures strongly modified due to the introduction of the alloying element. We consider HMAs where the isolated state of the alloying element is near the host conduction band, which causes the conduction band to split into two bands. We determine the bulk plasma frequency when the lower-energy band is partially occupied, as by doping, using a semi-analytical method based on a disorder-averaged Green's function. We include the nontrivial effects of interband transitions to the higher-energy band, which limit the plasma frequency to be less than an effective band gap. We show that the distribution of states in the split bands causes plasmons in HMAs to behave differently than plasmons in standard metals and semiconductors. The effective mass of the lower split band $m^*$ changes with alloy fraction, and we find that the plasmon frequency with small carrier concentration $n$ scales with $\sqrt{n}/m^*$ rather than the $\sqrt{n/m^*}$ that is expected in standard materials. We suggest experiments to observe these phenomena. Considering the typical range of material parameters in this group of alloys and taking a realistic example, we suggest that HMAs can serve as highly tunable low-frequency plasmonic materials.
description: 10 pages, 6 figures
Candida auris en France en 2023 : épidémiologie nationale, diagnostic, prévention
Creators: name: Bigot*, Jeanne
name: Desnos-Ollivier*, Marie
name: Parneix*, Pierre
name: Berger-Carbonne, Anne
name: Lanternier, Fanny
name: Botterel, Françoise
name: Alanio, Alexandre
Publisher: name: Health & Co
Year: 2024
Subjects: Épidémiologie
Diagnostic
Dépistage
Résistance aux antibiotiques

description: L’émergence de Candida auris, levure pathogène qui peut devenir multi­résistante, représente une menace non négligeable pour la santé mondiale. Contrairement à la plupart des autres espèces de Candida, C. auris est facilement transmise dans les établissements de soins et provoque ainsi des épidémies. Le but de cet article est de répertorier et synthétiser les dernières données de la littérature concernant Candida auris, et plus précisément son épidémiologie française, ainsi que les recommandations émises pour son dépistage, sa prévention et son diagnostic.
Population variation in Neonicotinoid tolerance in nymphs of the Stenonema species complex of mayflies
Creators: name: D. Riley Rackliffe
name: Hoverman, Jason
Publisher: name: F1000 Research Limited
Year: 2019

description: Presents data from a survey of populations of stenonema/stenacron mayflies across the state of Indiana in terms of their EC50 values relating to the neonicotinoids Clothianidin and Thiamethoxam.
Evaluation of a sesquiterpene as possible drug lead against gelatinases via molecular dynamics simulations
Creators: name: Sehrish Jamal
name: Ahmed, Ayaz
name: Moin, Syed Tarique
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Malignant tumors can be targeted by accounting for their metastatic capabilities. Matrix metalloproteinases (MMPs) are the key players in tumor metastasis facilitating through their proteolytic activities of angiogenesis and extracellular matrix components (ECM) degradation. MMP-2 and MMP-9 being the members of a distinguished class of MMPs more commonly known as gelatinases are the prominent enzymes which are involved in different cancer progression stages. Targeting these isoforms specifically has always been a challenging task due to highly similar structural and functional features among the other members of MMPs with well preserve active sites containing catalytic zinc atom that was the only reason that none of the MMP inhibitor has been successfully marketed for the tumor pathology up till now. Therefore, non-competitive inhibitors with different structural attributed are needed to be evaluated at the molecular level for further experiments. The present study deals with the application of molecular dynamics simulation for the investigation of an alternative pathway for the inhibition of MMP-2 and MMP-9 by a sesquiterpene isolated from Polygonum barbatum which demonstrates the characteristics binding to the S1′ subsite of the enzymes followed by in vitro gene expression studies. The simulation results provide information on the possible binding profile producing inhibitory effects imposed by the inhibitor to these enzymes by acquiring different structural and dynamical features. Moreover, thermodynamic quantities based on the computationally intensive thermodynamic integration approach were also obtained in terms of inhibitor binding affinity computed for the inhibitor against MMP-2 and MMP-9 that completely augmented the experimental gene expression study. Communicated by Ramaswamy H. Sarma
Are quasar jets dominated by Poynting flux?
Creators: name: Sikora, Marek
name: Begelman, Mitchell C.
name: Madejski, Greg M.
name: Lasota, Jean-Pierre
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The formation of relativistic astrophysical jets is presumably mediated by magnetic fields threading accretion disks and central, rapidly rotating objects. As it is accelerated by magnetic stresses, the jet's kinetic energy flux grows at the expense of its Poynting flux. However, it is unclear how efficient is the conversion from magnetic to kinetic energy and whether there are any observational signatures of this process. We address this issue in the context of jets in quasars. Using data from all spatial scales, we demonstrate that in these objects the conversion from Poynting-flux-dominated to matter-dominated jets is very likely to take place closer to the black hole than the region where most of the Doppler boosted radiation observed in blazars is produced. We briefly discuss the possibility that blazar activity can be induced by global MHD instabilities, e.g., via the production of localized velocity gradients that lead to dissipative events such as shocks or magnetic reconnection, where acceleration of relativistic particles and production of non-thermal flares is taking place.
description: Accepted by the Astrophysical Journal
Doubling bialgebras of finite topologies
Creators: name: Ayadi, Mohamed
name: Manchon, Dominique
Publisher: name: arXiv
Year: 2020
Subjects: subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: The species of finite topological spaces admits two graded bimonoid structures, recently defined by F. Fauvet, L. Foissy, and the second author. In this article, we define a doubling of this species in two different ways. We build a bimonoid structure on each of these species and describe a cointeraction between them. We also investigate two related associative products obtained by dualisation.
description: Version 3. Extended introduction and bibliography
The importance of team skills for software development
Creators: name: Wick, Carolyn Tanya
Publisher: name: University of British Columbia
Year: 2009

description: Software does not just happen - it must be engineered systematically through the collaboration of individuals with necessary software development skills and appropriate tools. Similarly, effective software teams do not just happen - they too are built over time through the collaboration of individuals with appropriate team skills, tools and resources. This thesis outlines the need for superior software teams, reviews the literature on team performance and argues that a practical way to begin improving the effectiveness of software teams is in training software engineers in the skills necessary for effective teamwork. A list of fundamental skills for software development is presented, including skills for team leaders interested in building effective software teams, and general-purpose team skills benefiting all software team members. The most important team skills for software development are described in detail, including: project management skills, meeting skills, asynchronous communication skills, interaction skills, conflict management skills, group problem-solving and decision-making skills, skills for understanding the user or customer, team-building skills, leadership, and process awareness. The thesis concludes with a case study of an undergraduate software engineering team project course, in which several initiatives were taken to observe the performance of software teams and to learn more about teaching team skills to software engineers. Some special skills needed for effectively teaching team skills are identified, and recommendations are offered to educators for modifying the undergraduate software engineering curriculum, as well as to software professionals in industry for engineering their own effective software teams.
Large-Scale Sidereal Anisotropy of Galactic Cosmic-Ray Intensity Observed by the Tibet Air Shower Array
Creators: name: The Tibet AS Gamma Collaboration
name: Amenomori, M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the large-scale sidereal anisotropy ofgalactic cosmic-ray intensity in the multi-TeV region observed with the Tibet-IIIair shower array during the period from 1999 through 2003. The sidereal daily variation of cosmic rays observed in this experiment shows an excess of relative intensity around $4\sim7 $ hours local sidereal time, as well as a deficit around 12 hours local sidereal time. While the amplitude of the excess is not significant when averaged over all declinations, the excess in individual declinaton bands becomes larger and clearer as the viewing direction moves toward the south. The maximum phase of the excess intensity changes from $\sim$7 at the northern hemisphere to $\sim$4 hours at the equatorial region. We also show that both the amplitude and the phase of the first harmonic vector of the daily variation are remarkably independent of primary energy in the multi-TeV region. This is the first result determining the energy and declination dependences of the full 24-hour profiles of the sidereal daily variation in the multi-TeV region with a single air shower experiment.
description: 13 pages, 3 figures, 1 table. Accepted for publication in ApJL
Goßmann, Klaus: Ökumenisches Lernen im Religionsunterricht
Creators: name: Hermann, Gunther J.
Publisher: name: Ökumenische Rundschau
Year: 2025

description: Ökumenische Rundschau, Bd. 38 Nr. 3 (1989): Ökumenische Rundschau, Band 38, Heft 3
Impact of mixed modes on measurement errors and estimates of change in panel data
Creators: name: Cernat, Alexandru
Publisher: name: European Survey Research Association
Year: 2015
Subjects: mixed modes; measurement model; latent growth models; panel data

description: Mixed mode designs are receiving increased interest as a possible solution for saving costs in panel surveys, although the lasting effects on data quality are unknown. To better understand the effects of mixed mode designs on panel data we will examine its impact on random and systematic error and on estimates of change. The SF12, a health scale, in the Understanding Society Innovation Panel is used for the analysis. Results indicate that only one variable out of 12 has systematic differences due to the mixed mode design. Also, four of the 12 items overestimate variance of change in time in the mixed mode design. We conclude that using a mixed mode approach leads to minor measurement differences but it can result in the overestimation of individual change compared to a single mode design.
description: Survey Research Methods, Vol 9, No 2 (2015)
Galactic merger implications for eccentric nuclear disks: a mechanism for disk alignment
Creators: name: Rodriguez, Alexander
name: Generozov, Aleksey
name: Madigan, Ann-Marie
Publisher: name: arXiv
Year: 2020
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The nucleus of our nearest, large galactic neighbor, M31, contains an eccentric nuclear disk--a disk of stars on eccentric, apsidally-aligned orbits around a supermassive black hole (SMBH). Previous studies of eccentric nuclear disks considered only an isolated disk, and did not study their dynamics under galaxy mergers (particularly a perturbing SMBH). Here, we present the first study of how eccentric disks are affected by a galactic merger. We perform N-body simulations to study the disk under a range of different possible SMBH initial conditions. A second SMBH in the disk always disrupts it, but more distant SMBHs can shut off differential precession and stabilize the disk. This results in a more aligned disk, nearly uniform eccentricity profile, and suppression of tidal disruption events compared to the isolated disk. We also discuss implications of our work for the presence of a secondary SMBH in M31.
description: 14 pages, 20 figures (19 in main text, 1 in Appendix), submitted to MNRAS
Synthesis of new morpholine containing 3-amido-9-ethylcarbazole derivative and studies on its biophysical interactions with calf thymus DNA/HSA
Creators: name: Kıpçak, Fulya
name: Tugba Taskın Tok
name: Duyar, Halil
name: Seferoğlu, Zeynel
name: Gökoğlu, Elmas
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: In this work, we presented the synthesis and investigation of the binding properties to calf thymus DNA (ctDNA) and human serum albumin (HSA) of the new morpholine containing 3-amido-9-ethylcarbazole derivative (CMR) by fluorescence spectroscopy, UV absorption spectroscopy and molecular docking method. A decrease in Stern Volmer constants was obtain with increasing temperature, it shows static quenching mechanism and new formation of CMR-DNA/HSA complexes which have hyrophobic interactions as the predominant role in the binding modes. Also, binding properties of DNA investigated with competition assays of two probes (EB and H33258), and absorption, ionic strength, iodide ion quenching. The results suggested that CMR entered into the minor groove binding with the A-T region of DNA. The spectral data further confirmed by molecular docking which elicited that CMR complexes have similiar interaction and conformation trends to each target, DNA and HSA. The experimental and computational results show that CMR can be classified as a promising molecule in drug design for other carbazole derivatives.
China–Pacific Tourism Engagement: Opportunities and Challenges
Creators: name: Zhang, Denghua
Publisher: name: Canberra, ACT: Dept. of Pacific Affairs, Coral Bell School of Asia Pacific Affairs, The Australian National University
Year: 2021

description: Tourism is a pillar industry in the Pacific, contributing 11.1 per cent of the region’s GDP, or US$3.8 billion, and creating 131,010 jobs in 2018 (South Pacific Tourism Organisation (SPTO) 2019:3). This In Brief argues that the increase in Chinese tourists to the Pacific in pre-COVID-19 times and China’s promotion of tourism cooperation as part of people-to-people links suggest opportunities for Pacific tourism industries after the pandemic. However, the challenges to these industries are notable, such as the decline of Chinese tourists to Palau, the ongoing COVID-19 pandemic and a lack of direct flights between China and Pacific Island countries (PICs).
The US's Indo-Pacific Strategy: Implications for Pacific Island Countries
Creators: name: Zhang, Denghua
Publisher: name: Canberra, ACT: Dept. of Pacific Affairs, Research School of Pacific and Asian Studies, The Australian National University
Year: 2018

description: The Indo-Pacific strategy is the Trump administration’s new policy on the region. Though its details remain unclear, this In Brief discusses the strategy’s nature and its implications for Pacific Island countries (PICs).
Evidence for Radial Expansion at the Core of the Orion Complex with Gaia EDR3
Creators: name: Swiggum, Cameren
name: D'Onghia, Elena
name: Alves, João
name: Großschedl, Josefa
name: Foley, Michael
name: Zucker, Catherine
name: Meingast, Stefan
name: Chen, Boquan
name: Goodman, Alyssa
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a phase-space study of two stellar groups located at the core of the Orion complex: Briceño-1 and Orion Belt Population-near (OBP-near). We identify the groups with the unsupervised clustering algorithm, Shared Nearest Neighbor (SNN), which previously identified twelve new stellar substructures in the Orion complex. For each of the two groups, we derive the 3D space motions of individual stars using Gaia EDR3 proper motions supplemented by radial velocities from Gaia DR2, APOGEE-2, and GALAH DR3. We present evidence for radial expansion of the two groups from a common center. Unlike previous work, our study suggests that evidence of stellar group expansion is confined only to OBP-near and Briceño-1 whereas the rest of the groups in the complex show more complicated motions. Interestingly, the stars in the two groups lie at the center of a dust shell, as revealed via an extant 3D dust map. The exact mechanism that produces such coherent motions remains unclear, while the observed radial expansion and dust shell suggest that massive stellar feedback could have influenced the star formation history of these groups.
description: Accepted for publication in ApJ. Stellar membership data to be available in published article
Data supplements for "Effects of combined substrate and oxygen oscillations on Escherichia coli"
Creators: name: Bafna-Rührer, Jonas
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310602
subject: Bioprocessing, bioproduction and bioproducts
classificationCode: 310114
subject: Systems biology

description: Data supplements of large files related to a scale-down study investigating the effect of oxygen and substrate oscillations on E. coli.
Ancient Names
Creators: name: Ochurte, Rufino
name: Mixco, Mauricio J.
Publisher: name: California Language Archive, University of California, Berkeley
Year: 2021
Subjects: subject: klb

description: See Kiliwa Texts: "When I have Donned My Crest of Stars" (University of Utah Press, 1983), p. 148 for transcription, segmentation, glossing, and translation of this story.
Widows and Wives in Pacific Politics: A Reliable Pathway for Women?
Creators: name: Baker, Kerryn
name: Palmieri, Sonia
Publisher: name: Canberra, ACT: Dept. of Pacific Affairs, Research School of Pacific and Asian Studies, The Australian National University
Year: 2020

description: Understanding women’s pathways to political leadership remains a critical area of academic and public policy focus in the Pacific. In this In Brief, Baker and Palmieri consider an alternate and potentially rather ‘macabre’ pathway (Kincaid 1978), albeit one which sheds light on the cultural and political economies of elections in the Pacific and which they believe requires further elucidation: the election of wives and widows of former members of parliament.
Abrupt Onset of Second Energy Gap at Superconducting Transition of Underdoped Bi2212
Creators: name: Lee, W. S.
name: Vishik, I. M.
name: Tanaka, K.
name: Lu, D. H.
name: Sasagawa, T.
name: Nagaosa, N.
name: Devereaux, T. P.
name: Hussain, Z.
name: Shen, Z. -X.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The superconducting gap - an energy scale tied to the superconducting phenomena-opens on the Fermi surface at the superconducting transition temperature (TC) in conventional BCS superconductors. Quite differently, in underdoped high-TC superconducting cuprates, a pseudogap, whose relation to the superconducting gap remains a mystery, develops well above TC. Whether the pseudogap is a distinct phenomenon or the incoherent continuation of the superconducting gap above TC is one of the central questions in high-TC research. While some experimental evidence suggests they are distinct, this issue is still under intense debate. A crucial piece of evidence to firmly establish this two-gap picture is still missing: a direct and unambiguous observation of a single-particle gap tied to the superconducting transition as function of temperature. Here we report the discovery of such an energy gap in underdoped Bi2212 in the momentum space region overlooked in previous measurements. Near the diagonal of Cu-O bond direction (nodal direction), we found a gap which opens at TC and exhibits a canonical (BCS-like) temperature dependence accompanied by the appearance of the so-called Bogoliubov quasiparticles, a classical signature of superconductivity. This is in sharp contrast to the pseudogap near the Cu-O bond direction (antinodal region) measured in earlier experiments. The emerging two-gap phenomenon points to a picture of richer quantum configurations in high temperature superconductors.
description: 16 pages, 4 figures, authors' version Corrected typos in the abstract
Permutable entire functions satisfying algebraic differential equations
Creators: name: Bergweiler, Walter
Publisher: name: arXiv
Year: 2005
Subjects: subject: Complex Variables (math.CV)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 30D05, 34M05, 39B12

description: It is shown that if two transcendental entire functions permute, and if one of them satisfies an algebraic differential equation, then so does the other one.
description: 5 pages
Predicting second virial coefficients of organic and inorganic compounds using Gaussian Process Regression
Creators: name: Cretu, Miruna T.
name: Pérez-Ríos, Jesús
Publisher: name: arXiv
Year: 2020
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic Physics (physics.atom-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We show that by using intuitive and accessible molecular features it is possible to predict the temperature-dependent second virial coefficient of organic and inorganic compounds using Gaussian process regression. In particular, we built a low dimensional representation of features based on intrinsic molecular properties, topology and physical properties relevant for the characterization of molecule-molecule interactions. The featurization was used to predict second virial coefficients in the interpolative regime with a relative error $\lesssim 1\% $ and to extrapolate the prediction to temperatures outside of the training range for each compound in the dataset with a relative error of 2.14\%. Additionally, the model's predictive abilities were extended to organic molecules unseen in the training process, yielding a prediction with a relative error of 2.66\%. Therefore, apart from being robust, the present Gaussian process regression model is extensible to a variety of organic and inorganic compounds.
A generalized theory of semiflexible polymers
Creators: name: Wiggins, Paul A.
name: Nelson, Philip C.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experimental studies of these biological systems have led to a renewed interest in the polymer mechanics relevant for describing the conformational free energy of DNA bending induced by protein-DNA complexes. Recent experimental results from DNA cyclization studies have cast doubt on the applicability of the canonical semiflexible polymer theory, the wormlike chain (WLC) model, to DNA bending on biological length scales. This paper develops a theory of the chain statistics of a class of generalized semiflexible polymer models. Our focus is on the theoretical development of these models and the calculation of experimental observables. To illustrate our methods, we focus on a specific toy model of DNA bending. We show that the WLC model generically describes the long-length-scale chain statistics of semiflexible polymers, as predicted by the Renormalization Group. In particular, we show that either the WLC or our new model adequate describes force-extension, solution scattering, and long-contour-length cyclization experiments, regardless of the details of DNA bend elasticity. In contrast, experiments sensitive to short-length-scale chain behavior can in principle reveal dramatic departures from the linear elastic behavior assumed in the WLC model. We demonstrate this explicitly by showing that our toy model can reproduce the anomalously large short-contour-length cyclization J factors observed by Cloutier and Widom. Finally, we discuss the applicability of these models to DNA chain statistics in the context of future experiments.
In silico identification of novel 5-HT2A antagonists supported with ligand- and target-based drug design methodologies
Creators: name: Radan, Milica
name: Dusan Ruzic
name: Antonijevic, Mirjana
name: Djikic, Teodora
name: Nikolic, Katarina
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: A wide range of neuropsychological disorders is caused by serotonin 5-HT2A receptor (5-HT2AR) malfunction. Therefore, this receptor had been frequently used as target in CNS drug research. To design novel potent 5-HT2AR antagonists, we have combined ligand-based and target-based approaches. This study was performed on wide range of structurally diverse antagonists that were divided into three different clusters: clozapine, ziprasidone, and ChEMBL240876 derivatives. By performing the 50 ns long molecular dynamic simulations with each cluster representative in complex with 5-HT2A receptor, we have obtained virtually bioactive conformations of the ligands and three different antagonist-bound, inactive, conformations of the 5-HT2AR. These three 5-HT2AR conformations were further used for docking studies and generation of the bioactive conformations of the data set ligands in each cluster. Subsequently, selected conformers were used for 3D-Quantitative Structure Activity Relationship (3D-QSAR) modelling and pharmacophore analysis. The reliability and predictive power of the created model was assessed using an external test set compounds and showed reasonable external predictability. Statistically significant variables were used to define the most important structural features required for 5-HT2A antagonistic activity. Conclusions obtained from performed ligand-based (3D-QSAR) and target-based (molecular docking and molecular dynamics) methods were compiled and used as guidelines for rational drug design of novel 5-HT2AR antagonists. Communicated by Ramaswamy H. Sarma
Mentoring to Support Women’s Leadership
Creators: name: Howard, Elise
name: Barbara, Julien
name: Palmieri, Sonia
Publisher: name: Canberra, ACT: Dept. of Pacific Affairs, Research School of Pacific and Asian Studies, The Australian National University
Year: 2020

description: Mentoring has become an increasingly common form of assistance used by development partners to support women’s leadership in Pacific Island contexts. This Policy Brief highlights the need for mentoring programs to be responsive to mentees’ goals, learning processes and local contexts. Currently, the design and implementation of mentoring programs in developing contexts are often underwritten by four key assumptions: that a mentor from a developed country can effectively and sustainably mentor a woman from a developing country context; that mentoring programs based outside a mentee’s specific workplace (and country) context can transcend local structural barriers to women’s leadership; that mentoring serves the same kinds of purposes in all contexts; and that mentoring methodologies used in corporate contexts can be implemented in developing contexts. These assumptions will be explored in this Policy Brief. In order to more strongly align mentoring with meaningful policy impact in a development context, we propose the following evidence-based recommendations: 1. Complement mentorship programs with other developmental leadership programs, recognising the limitations of programs focused only on change driven by individuals. 2. Facilitate opportunities for women to find their own context-relevant mentors. 3. Match clearly, at the outset of the program, a woman’s leadership objectives with the mentoring purpose. 4. Provide ongoing support to develop and strengthen mentoring relationships. 5. Support mentors to critically challenge and support the leadership aspirations and capacities of mentees within their sphere of influence. 6. Recognise the long-term and transitional nature of mentoring relationships.
Hamiltonian 2-forms in Kahler geometry, III Extremal metrics and stability
Creators: name: Apostolov, Vestislav
name: Calderbank, David M. J.
name: Gauduchon, Paul
name: Tonnesen-Friedman, Christina W.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Differential Geometry (math.DG)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 53C55; 53C25, 32J27

description: This paper concerns the explicit construction of extremal Kaehler metrics on total spaces of projective bundles, which have been studied in many places. We present a unified approach, motivated by the theory of hamiltonian 2-forms (as introduced and studied in previous papers in the series) but this paper is largely independent of that theory. We obtain a characterization, on a large family of projective bundles, of those `admissible' Kaehler classes (i.e., the ones compatible with the bundle structure in a way we make precise) which contain an extremal Kaehler metric. In many cases, such as on geometrically ruled surfaces, every Kaehler class is admissible. In particular, our results complete the classification of extremal Kaehler metrics on geometrically ruled surfaces, answering several long-standing questions. We also find that our characterization agrees with a notion of K-stability for admissible Kaehler classes. Our examples and nonexistence results therefore provide a fertile testing ground for the rapidly developing theory of stability for projective varieties, and we discuss some of the ramifications. In particular we obtain examples of projective varieties which are destabilized by a non-algebraic degeneration.
description: 40 pages, sequel to math.DG/0401320 and math.DG/0202280, but largely self-contained; partially replaces and extends math.DG/0501516