cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Aboriginal community controlled health organisations address health equity through action on the social determinants of health of Aboriginal and Torres Strait Islander peoples in Australia
Creators: name: Pearson, O.
name: K. Schwartzkopff
name: A. Dawson
name: C. Hagger
name: A. Karagi
name: C. Davy
name: A. Brown
name: A. Braunack-Mayer
Publisher: name: figshare
Year: 2020
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1. Activities delivered by ACCHOs to specific population groups. The population groups that ACCHO delivered activities to.
Additional file 1 of Emergency and urgent dental visits among Medicaid enrollees from 2013 to 2017
Creators: name: Fiehn, Rebekah
name: Okunev, Ilya
name: Bayham, Mary
name: Barefoot, Steven
name: Tranby, Eric P.
Publisher: name: figshare
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1. Top 20 Procedure Codes During Emergency Visits and Visit after an Emergency Visit.
Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation
Creators: name: Lynch, Catherine
name: Tycko, Benjamin
name: Bestor, Timothy H.
name: Walsh, Colum
Publisher: name: Columbia University
Year: 2002
Subjects: subject: Rhabdomyosarcoma
subject: DNA--Methylation
subject: Genetics
subject: FOS: Biological sciences
subject: Cytology

description: Background: The active copy of the imprinted gene H19 is turned off by inappropriate methylation in several pediatric tumors including Wilms' Tumour and embryonal rhabdomyosarcoma. H19 controls in cis the linked Insulin-like Growth Factor 2 (IGF2) gene, encoding an important growth factor. Recent work has suggested that methylation of a gene may lead to deacetylation of its associated histones and that silenced genes can be reactivated by increasing histone acetylation levels. Results: Treatment of a rhabdomyosarcoma cell line which has a silent, methylated H19 gene with histone deacetylase (HDAC) inhibitors under conditions which gave maximal hyperacetylation of histone 4, both globally and at the H19 gene itself could not reactivate H19 or affect the active Insulin-like Growth Factor 2 (IGF2) gene, but caused clear up-regulation of the Tissue-type Plasminogen Activator (TPA) gene, a non-imprinted gene known to respond to changes in histone acetylation. In contrast, mild treatment of the cells with the methylation inhibitor 5-AzaC-2'-deoxycytidine (AzaC) on its own was able to reactivate H19. Combining AzaC treatment with HDAC inhibitors gave a reduced rather than enhanced reactivation. These findings were confirmed in mouse primary liver and kidney explants which maintain normal imprinting, where we also found that the silent Igf2 gene could not be reactivated by HDAC inhibitors. Conclusion: These results suggest that DNA methylation rather than histone acetylation is the primary determinant of silencing of H19 in rhabdomyosarcoma.
Monic integer Chebyshev problem
Creators: name: Borwein, P. B.
name: Pinner, C. G.
name: Pritsker, I. E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: Primary 11C08, Secondary 30C10

description: We study the problem of minimizing the supremum norm by monic polynomials with integer coefficients. Let ${\M}_n({\Z})$ denote the monic polynomials of degree $n$ with integer coefficients. A {\it monic integer Chebyshev polynomial} $M_n \in {\M}_n({\Z})$ satisfies $$ \| M_n \|_{E} = \inf_{P_n \in{\M}_n ({\Z})} \| P_n \|_{E}. $$ and the {\it monic integer Chebyshev constant} is then defined by $$ t_M(E) := \lim_{n \rightarrow \infty} \| M_n \|_{E}^{1/n}. $$ This is the obvious analogue of the more usual {\it integer Chebyshev constant} that has been much studied. We compute $t_M(E)$ for various sets including all finite sets of rationals and make the following conjecture, which we prove in many cases. \medskip\noindent {\bf Conjecture.} {\it Suppose $[{a_2}/{b_2},{a_1}/{b_1}]$ is an interval whose endpoints are consecutive Farey fractions. This is characterized by $a_1b_2-a_2b_1=1.$ Then} $$t_M[{a_2}/{b_2},{a_1}/{b_1}] = \max(1/b_1,1/b_2).$$ This should be contrasted with the non-monic integer Chebyshev constant case where the only intervals where the constant is exactly computed are intervals of length 4 or greater.
Additional file 1 of Maternal iodine status in a multi-ethnic UK birth cohort: associations with autism spectrum disorder
Creators: name: Cromie, Kirsten Jade
name: Threapleton, Diane Erin
name: Snart, Charles Jonathan Peter
name: Taylor, Elizabeth
name: Mason, Dan
name: Wright, Barry
name: Kelly, Brian
name: Reid, Stephen
name: Rafaq Azad
name: Keeble, Claire
name: Waterman, Amanda H.
name: Meadows, Sarah
name: McKillion, Amanda
name: Nisreen A. Alwan
name: Cade, Janet Elizabeth
name: Simpson, Nigel A. B.
name: Stewart, Paul M.
name: Zimmermann, Michael
name: Wright, John
name: Waiblinger, Dagmar
name: Mon-Williams, Mark
name: Hardie, Laura J.
name: Greenwood, Darren Charles
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
Furrows in the wake of propagating d-cones
Creators: name: Gottesman, Omer
name: Efrati, Efi
name: Rubinstein, Shmuel M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate the formation dynamics of plastic creases in thin elasto-plastic sheets. In contrast to the commonly accepted description of crumpled thin sheets, which asserts that creases form only by elastic interaction between two d-cones, the creases we study in this letter are created by plastic deformations left in the wake of a single propagating d-cone. Upon application of load, a d-cone initially remains stationary and responds by deforming globally. However, above a critical load, the d-cone undergoes a sharpening transition that focuses the stresses at its tip, allowing it to propagate along the sheet, leaving a furrow-like scar in its wake. Our results show that the dynamics of plastic defect creation are important for predicting the final geometry and statistics of a defect network in a crumpled thin sheet.
description: 4 pages, 4 figures
Canister valve and actuator deposition in metered dose inhalers formulated with low-GWP propellants
Creators: name: Duke, Daniel J
name: Rao, Lingzhe
name: Kastengren, Alan
name: Myatt, Benjamin
name: Cocks, Phil
name: Stein, Stephen
name: Marasini, Nirmal
name: Ong, Hui Xin
name: Young, Paul
Publisher: name: arXiv
Year: 2023
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: A challenge in pressurised metered-dose inhaler formulation design is management of adhesion of the drug to the canister wall, valve and actuator internal components and surfaces, especially for sedimenting or creaming suspensions. Visual analysis of drug solubility and suspension behavior is typically performed in transparent vials. If the results are affected strongly by wall-material interactions, they may not be replicable in typical metal canister pMDI systems. This is of particular concern in low-greenhouse warming potential (GWP) propellant formulations where the chemistry of the new propellants and solubility with many drugs is not yet fully understood. The same can be extended to deposition in actuator and valve components, which are generally opaque. In this study, we demonstrate a novel application of X-ray fluorescence spectroscopy using synchrotron radiation to assay the contents of surrogate solution and suspension pMDI formulations of potassium iodide and barium sulfate in propellants HFA134a, HFA152a and HFO1234ze(E) using standard components. Through unit life drug distribution in the canister valve closure region and actuator can vary more significantly with new propellants. These effects must be taken into consideration in the development of products utilising low-GWP propellants.
description: 26 pages, 14 figures, preprint submitted for peer review Sept. 2023
A Rubber-Modified Thermoplastic where the Morphology Produced by Phase-Separation Induced by Polymerization Disappears at High Conversions
Creators: name: Soule, E. R.
name: Elicabe, G. E.
name: Williams, R. J. J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: An unexpected experimental finding is reported where the primary morphology developed during polymerization-induced phase separation in a rubber-modified thermoplastic disappears at high conversions. This process was evidenced by light scattering (LS) and scanning electron microscopy (SEM) for a particular composition of solutions of polyisobutylene oligomers (PIB) in isobornylmethacrylate (IBoMA), during the free-radical polymerization of the monomer. The primary phase separation produced a dispersion of domains rich in PIB containing significant amounts of the monomer (IBoMA). Polymerization of the monomer in these domains occurred at high overall conversions producing the filling of dispersed domains with a PIBoMA-PIB blend. Under these conditions the final material had the appearance of a homogeneous blend. The process might be adapted to produce new types of rubber-modified thermoplastics where rubber particles are replaced by rubber-rich domains that do not exhibit definite boundaries. Keywords:
description: This is the author's version of an article published in Polymer Bulletin (Springer), available online at http://link.springer.com/article/10.1007/s00289-007-0882-6
Singular Bohr-Sommerfeld conditions for 1D Toeplitz operators: hyperbolic case
Creators: name: Floch, Yohann Le
Publisher: name: arXiv
Year: 2013
Subjects: subject: Spectral Theory (math.SP)
subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: In this article, we state the Bohr-Sommerfeld conditions around a singular value of hyperbolic type of the principal symbol of a self-adjoint semiclassical Toeplitz operator on a compact connected Kähler surface. These conditions allow the description of the spectrum of the operator in a fixed size neighbourhood of the singularity. We provide numerical computations for three examples, each associated to a different topology.
Attosecond Photoscopy of Plasmonic Excitations
Creators: name: Lupetti, Mattia
name: Hengster, Julia
name: Uphues, Thorsten
name: Scrinzi, Armin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We propose an experimental arrangement to image, with attosecond resolution, transient surface plasmonic excitations. The required modifications to state-of-the-art setups used for attosecond streaking experiments from solid surfaces only involve available technology. Buildup and life times of surface plasmon polaritons can be extracted and local modulations of the exciting optical pulse can be diagnosed {\it in situ}.
description: Article + Supplementary Material
GeoDEN: A Visual Exploration Tool for Analysing the Geographic Spread of Dengue Serotypes
Creators: name: Marler, Aidan
name: Roell, Yannik
name: Knoblauch, Steffen
name: Messina, Jane P.
name: Jaenisch, Thomas
name: Karimzadeh, Morteza
Publisher: name: arXiv
Year: 2025
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Static maps and animations remain popular in spatial epidemiology of dengue, limiting the analytical depth and scope of visualisations. Over half of the global population live in dengue endemic regions. Understanding the spatiotemporal dynamics of the four closely related dengue serotypes, and their immunological interactions, remains a challenge at a global scale. To facilitate this understanding, we worked with dengue epidemiologists in a user-centered design framework to create GeoDEN, an exploratory visualisation tool that empowers experts to investigate spatiotemporal patterns in dengue serotype reports. The tool has several linked visualisations and filtering mechanisms, enabling analysis at a range of spatial and temporal scales. To identify successes and failures, we present both insight-based and value-driven evaluations. Our domain experts found GeoDEN valuable, verifying existing hypotheses and uncovering novel insights that warrant further investigation by the epidemiology community. The developed visual exploration approach can be adapted for exploring other epidemiology and disease incident datasets.
Approximation of conformal mapping via the Szegő kernel method
Creators: name: Pritsker, Igor E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: Primary 30C40, 30E10, Secondary 41A10, 30C30

description: We study the uniform approximation of the canonical conformal mapping, for a Jordan domain onto the unit disk, by polynomials generated from the partial sums of the Szegő kernel expansion. These polynomials converge to the conformal mapping uniformly on the closure of any Smirnov domain. We prove estimates for the rate of such convergence on domains with piecewise analytic boundaries, expressed through the smallest exterior angle at the boundary. Furthermore, we show that the rate of approximation on compact subsets inside the domain is essentially the square of that on the closure. Two standard applications to the rate of decay for the contour orthogonal polynomials inside the domain, and to the rate of locally uniform convergence of Fourier series are also given.
The SOFIA FEEDBACK Legacy Survey: Rapid molecular cloud dispersal in RCW 79
Creators: name: Bonne, L.
name: Kabanovic, S.
name: Schneider, N.
name: Zavagno, A.
name: Keilmann, E.
name: Simon, R.
name: Buchbender, C.
name: Guesten, R.
name: Jacob, A. M.
name: Jacobs, K.
name: Kavak, U.
name: Polles, F. L.
name: Tiwari, M.
name: Wyrowski, F.
name: Tielens, A. G. G. M
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: It has long been discussed whether stellar feedback in the form of winds and/or radiation can shred the nascent molecular cloud, thereby controlling the star formation rate. However, directly probing and quantifying the impact of stellar feedback on the neutral gas of the nascent clouds is challenging. We present an investigation doing exactly that toward the RCW 79 HII region using the ionized carbon line at 158 $μ$m ([CII]) from the FEEDBACK Legacy Survey. We combine this data with information on the dozen ionizing O stars responsible for the evolution of the region, and observe in [CII] for the first time both blue- and red-shifted mostly neutral high-velocity gas which reaches velocities up to 25 km s$^{-1}$ relative to the bulk emission of the molecular cloud. This high-velocity gas mostly contains neutral gas and partly forms a fragmented shell, similar to recently found shells in a few Galactic HII regions. However, this shell does not account for all of the observed neutral high-velocity gas. We also find high-velocity gas streaming out of the nascent cloud through holes and obtain a range of dynamical timescales below 1.0 Myr for the high-velocity gas which is well below the 2.3$\pm$0.5 Myr age of the OB cluster. This suggests a different scenario for the evolution of RCW 79, where the high-velocity gas is not solely stemming from a spherical expanding bubble, but also from gas recently ablated at the edge of the turbulent molecular cloud into the surrounding interstellar medium through low-pressure holes or chimneys. The resulting mass ejection rate estimate for the cloud is 0.9-3.5$\times$10$^{-2}$ M$_{\odot}$~yr$^{-1}$, which leads to short erosion timescales, i.e. $<$5 Myr, for the nascent molecular cloud. This finding provides direct observational evidence of rapid molecular cloud dispersal.
description: 9 pages, 7 figures, accepted in A&A Letters
ENHANCING INTERPRETABILITY AND ADAPTABILITY OF MANUFACTURING EQUIPMENT HEALTH MODELS AND ESTABLISHMENT OF COST MODELS FOR MAINTENANCE DECISIONS
Creators: name: Wu, Haiyue
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: Manufacturing processes and technologies (excl. textiles)
Deep learning
Environmentally sustainable engineering
Artificial intelligence not elsewhere classified

description: The integration of Industry 4.0 technologies such as cyber-physical systems, the internet of things, and artificial intelligence has revolutionized the traditional manufacturing systems, making them smart and digital. Maintenance, a critical component of manufacturing, has been incorporated with data-driven strategies such as prognostic and health management (PHM) to improve production efficiency and reliability. This is achieved by real-time sensing and AI-based modeling, which monitor the health condition of operational equipment for fault detection or failure prediction. The results generated by these models provide crucial support for decision-making processes in manufacturing, ranging from maintenance scheduling to production management. This research focuses on data-driven machine health models based on deep learning in manufacturing systems and explores three directions towards the practical implementation of PHM: model interpretation, model adaptability and robustness enhancement, and cost-benefit analysis of maintenance strategies. In terms of model interpretation, the RNN-LSTM-based model prediction on bearing health estimation was analyzed, and the relationship between the model input and output was investigated. The adoption of the LRP technique improved the explainability of the LSTM model beyond predictive maintenance applications. To enhance model adaptability and robustness, a Transformer-based method was developed for fault diagnosis and novel fault detection, which achieved superior performance compared to conventional fault classification AI-based models. The decision-making aspect of PHM was addressed by conducting a cost-benefit analysis on different maintenance strategies, which provided a new perspective for decision-makers in maintenance management.
Genetic and spectrally distinct in vivo imaging: embryonic stem cells and mice with widespread expression of a monomeric red fluorescent protein
Creators: name: Long, Jonathan Z.
name: Lackan, Chantal
name: Hadjantonakis, Anna-Katerina
Publisher: name: Columbia University
Year: 2005
Subjects: subject: Transgenes--Expression
subject: Embryonic stem cells
subject: Genetics
subject: FOS: Biological sciences
subject: Developmental biology

description: Background: DsRed the red fluorescent protein (RFP) isolated from Discosoma sp. coral holds much promise as a genetically and spectrally distinct alternative to green fluorescent protein (GFP) for application in mice. Widespread use of DsRed has been hampered by several issues resulting in the inability to establish and maintain lines of red fluorescent protein expressing embryonic stem cells and mice. This has been attributed to the non-viability, or toxicity, of the protein, probably as a result of its obligate tetramerization. A mutagenesis approach directing the stepwise evolution of DsRed has produced mRFP1, the first true monomer. mRFP1 currently represents an attractive autofluorescent reporter for use in heterologous systems. Results: We have used embryonic stem cell-mediated transgenesis to evaluate mRFP1 in embryonic stem cells and mice. We find that mRFP1 exhibits the most spatially homogenous expression when compared to the native (tetrameric) and variant dimeric forms of DsRed. High levels of mRFP1 expression do not affect cell morphology, developmental potential or viability and fertility of animals. High levels of widespread mRFP1 expression are maintained in a constitutive manner in embryonic stem cells in culture and in transgenic animals. We have used various optical imaging modalities to visualize mRFP1 expressing cells in culture, in embryos and adult mice. Moreover co-visualization of red, green and cyan fluorescent cells within a sample is easily achieved without the need for specialized methodologies, such as spectral deconvolution or linear unmixing. Conclusion: Fluorescent proteins with excitation and/or emission profiles in the red part of the visible spectrum represent distinct partners, or longer wavelength substitutes for GFP. Not only do DsRed-based RFPs provide a genetically and spectrally distinct addition to the available repertoire of autoflorescent proteins, but by virtue of their spectral properties they permit deeper tissue imaging. Our work in generating CAG::mRFP1 transgenic ES cells and mice demonstrates the developmental neutrality of mRFP1 in an organismal context. It paves the way for the use of DsRed-based monomeric RFPs in transgenic and gene targeted approaches which often necessitate spatially and/or temporally restricted reporter expression. Moreover animals of the CAG::mRFP1 transgenic strain serve as a source of RFP tagged tissue for the derivation of cell lines and explant, transplant and embryo chimera experiments.
One-dimensional disordered Ising models by replica and cavity methods
Creators: name: Lucibello, Carlo
name: Morone, Flaviano
name: Rizzo, Tommaso
Publisher: name: arXiv
Year: 2014
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Using a formalism based on the spectral decomposition of the replicated transfer matrix for disordered Ising models, we obtain several results that apply both to isolated one-dimensional systems and to locally tree-like graph and factor graph (p-spin) ensembles. We present exact analytical expressions, which can be efficiently approximated numerically, for many types of correlation functions and for the average free energies of open and closed finite chains. All the results achieved, with the exception of those involving closed chains, are then rigorously derived without replicas, using a probabilistic approach with the same flavour of cavity method.
Composition of giant planets: the roles of pebbles and planetesimals
Creators: name: Danti, Claudia
name: Bitsch, Bertram
name: Mah, Jingyi
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: One of the current challenges of planet formation theory is to explain the enrichment of observed exoplanetary atmospheres. Past studies have focused on scenarios where either pebbles or planetesimals were the heavy element enrichment's drivers, we combine here both approaches to understand whether the composition of a planet can constrain its formation pathway. We study three different formation scenarios: pebble accretion, pebble accretion with planetesimal formation, combined pebble and planetesimal accretion. We use the chemcomp code to perform semi-analytical 1D simulations of protoplanetary discs, including viscous evolution, pebble drift, and simple chemistry to simulate the growth of planets from planetary embryos to gas giants as they migrate through the disc, while tracking their composition. Our simulations confirm that the composition of the planetary atmosphere is dominated by the accretion of gas enriched by inward drifting and evaporating pebbles. Including planetesimal formation hinders the enrichment, because the pebbles locked into planetesimals cannot evaporate and enrich the disc. This results in a big drop of the accreted heavy elements both in the planetesimal formation and accretion case, proving that planetesimal formation needs to be inefficient in order to explain planets with high heavy element content. Accretion of planetesimals enhances the refractory component of the atmosphere, leading to low volatile to refractory ratios, contrary to the pure pebble scenario. Such low volatile to refractory ratios can also be achieved by planets migrating in the inner disc in pure pebble scenario. Distinguishing these two scenarios requires knowledge about the planet's atmospheric C/H and O/H ratios, which are higher for pure pebble accretion. Therefore, a detailed knowledge of the composition of planetary atmospheres could help to constrain the planet's formation pathway.
description: 12 pages, 10 figures, accepted for publication in Astronomy and Astrophysics
BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data
Creators: name: Saal, Lao H.
name: Troein, Carl
name: Vallon-Christersson, Johan
name: Gruvberger, Sofia
name: Borg, Åke
name: Peterson, Carsten
Publisher: name: Columbia University
Year: 2002
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: DNA microarrays
subject: Cytology
subject: Genetics
subject: FOS: Biological sciences

description: The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their extracted data matrices, and information about the physical array, the features and reporter molecules. We present a web-based customizable bioinformatics solution called BioArray Software Environment (BASE) for the management and analysis of all areas of microarray experimentation. All software necessary to run a
local server is freely available.
Prospects for Charged Current Deep-Inelastic Scattering off Polarized Nucleons at a Future Electron-Ion Collider
Creators: name: Aschenauer, Elke C.
name: Burton, Thomas
name: Martini, Till
name: Spiesberger, Hubert
name: Stratmann, Marco
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present a detailed phenomenological study of charged-current-mediated deep-inelastic scattering off longitudinally polarized nucleons at a future Electron-Ion Collider. A new version of the event generator package DJANGOH, extended by capabilities to handle processes with polarized nucleons, is introduced and used to simulate charged current deep-inelastic scattering including QED, QCD, and electroweak radiative effects. We carefully explore the range of validity and the accuracy of the Jacquet-Blondel method to reconstruct the relevant kinematic variables from the measured hadronic final state in charged current events, assuming realistic detector performance parameters. Finally, we estimate the impact of the simulated charged current single-spin asymmetries on determinations of helicity parton distributions in the context of a global QCD analysis at next-to-leading order accuracy.
description: 12 pages, 10 eps figures
Thryonomyidae Pocock 1922
Creators: name: Honacki, James H.
name: Kinman, Kenneth E.
name: Koeppl, James W.
Publisher: name: Zenodo
Year: 1982
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Thryonomyidae

description: Family Thryonomyidae REVIEWED BY: Editors. ISIS NUMBER: 5301410030000000000.
description: Published as part of James H. Honacki, Kenneth E. Kinman & James W. Koeppl, 1982, Order Rodentia (Part 6), pp. 560-594 in Mammal Species of the World (1 st Edition), Lawrence, Kansas, USA :Alien Press, Inc. & The Association of Systematics Collections on page 592, DOI: 10.5281/zenodo.7353039
Additional file 1 of ABCDE cognitive aid tool in patient assessment – development and validation in a multicenter pilot simulation study
Creators: name: Peran, David
name: Jiri Kodet
name: Pekara, Jaroslav
name: Mala, Lucie
name: Truhlar, Anatolij
name: Cmorej, Patrik Christian
name: Lauridsen, Kasper Glerup
name: Sari, Ferenc
name: Sykora, Roman
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 1. Description of Scenario 1 and Scenario 2.
A Phase I Trial of Pox PSA vaccines (PROSTVAC®-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM™) in Patients with Prostate Cancer
Creators: name: DiPaola, RS
name: Plante, M
name: Kaufman, H
name: Petrylak, Daniel P.
name: Israeli, R
name: Lattime, E
name: Manson, K
name: Schuetz, T
Publisher: name: Columbia University
Year: 2006
Subjects: Prostate--Cancer
Vaccines
Medicine
Oncology

description: Purpose: Based on previous studies that demonstrated the safety profile and preliminary clinical activity of prostate specific antigen (PSA) targeted therapeutic vaccines, as well as recent laboratory data supporting the value of the addition of co-stimulatory molecules B7-1, ICAM-1, and LFA-3 (designated TRICOM™) to these vaccines, we conducted a Phase I study to evaluate the safety and immunogenicity of a novel vaccinia and fowlpox vaccine incorporating the PSA gene sequence and TRICOM. Methods: In this study, ten patients with androgen independent prostate cancer with or without metastatic disease were enrolled. Patients were treated with 2 × l08 pfu of a recombinant vaccinia virus vaccine (PROSTVAC-V) followed by 1 × 109 pfu of the booster recombinant fowlpox virus (PROSTVAC-F) both with gene sequences for PSA and TRICOM. The mean age of patients enrolled in the study was 70 (range 63 to 79). The mean PSA at baseline was 434 (range 9 - 1424). Results: There were no deaths, and no Grade 3 or 4 adverse events. The most commonly reported adverse events, regardless of causality, were injection site reactions and fatigue. One serious adverse event (SAE) occurred that was unrelated to vaccine; this patient developed progressive disease with a new sphenoid metastasis. PSA was measured at week 4 and week 8. Four patients had stable disease (with less than 25% increase in PSA) through the week 8 study period. Anti-PSA antibodies were not induced with therapy: however, anti-vaccinia titers increased in all patients. Conclusion: This study demonstrated that vaccination with PROSTVAC-V and PROSTVAC-F combined with TRICOM is well-tolerated and generated an immune response to vaccinia. Therefore, PROSTVAC-VF/TRICOM represents a feasible therapeutic approach for further phase II and III study in patients with prostate cancer.
Searching for [CII] Emission from the First Sample of $z\sim 6$ OI Absorption-Associated Galaxies with ALMA
Creators: name: Wu, Yunjing
name: Cai, Zheng
name: Li, Jianan
name: Finlator, Kristian
name: Neeleman, Marcel
name: Prochaska, J. Xavier
name: Emonts, Bjorn H. C.
name: Zhang, Shiwu
name: Wang, Feige
name: Yang, Jinyi
name: Wang, Ran
name: Fan, Xiaohui
name: Xu, Dandan
name: Golden-Marx, Emmet
name: Keating, Laura C.
name: Hennawi, Joseph F.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We report the first statistical analyses of [CII] and dust continuum observations in six strong OI absorber fields at the end of the reionization epoch obtained by the Atacama Large Millimeter/Submillimeter Array (ALMA). Combined with one [CII] emitter reported in Wu et al. (2021), we detect one OI-associated [CII] emitter in six fields. At redshifts of OI-absorbers in non-detection fields, no emitters are brighter than our detection limit within impact parameters of 50 kpc and velocity offsets between $\pm200\ {\rm km\ s^{-1}}$. The averaged [CII]-detection upper limit is $< 0.06$ Jy ${\rm km\ s^{-1}}$ (3$σ$), corresponding to the [CII] luminosity of $L_{\rm [CII]} <5.8\times 10^7\ L_{\odot}$ and the [CII]-based star formation rate of ${\rm SFR_{\rm [CII]}} < 5.5$ $M_\odot$ yr$^{-1}$. Cosmological simulations suggest that only $\sim10^{-2.5}$ [CII] emitters around [OI] absorbers have comparable SFR to our detection limit. Although the detection in one out of six fields is reported, an order of magnitude number excess of emitters obtained from our ALMA observations supports that the contribution of massive galaxies that caused the metal enrichment cannot be ignored. Further, we also found 14 tentative galaxy candidates with S/N of $\approx4.3$ at large impact parameters ($>50$ kpc) and having larger outflow velocities within $\pm 600$ km s$^{-1}$. If these detections are confirmed in the future, then the mechanism of pushing metals at larger distances with higher velocities needs to be further explored from the theoretical side.
description: Accepted for publication in ApJ. Main text 10 pages, 5 figures
Efficient Continuous-Duty Bitter-Type Electromagnets for Cold Atom Experiments
Creators: name: Sabulsky, Dylan
name: Parker, Colin V.
name: Gemelke, Nathan D.
name: Chin, Cheng
Publisher: name: arXiv
Year: 2013
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We present the design, construction and characterization of Bitter-type electromagnets which can generate high magnetic fields under continuous operation with efficient heat removal for cold atom experiments. The electromagnets are constructed from a stack of alternating layers consisting of copper arcs and insulating polyester spacers. Efficient cooling of the copper is achieved via parallel rectangular water cooling channels between copper layers with low resistance to flow; a high ratio of the water-cooled surface area to the volume of copper ensures a short length scale ~1 mm to extract dissipated heat. High copper fraction per layer ensures high magnetic field generated per unit energy dissipated. The ensemble is highly scalable and compressed to create a watertight seal without epoxy. From our measurements, a peak field of 770 G is generated 14 mm away from a single electromagnet with a current of 400 A and a total power dissipation of 1.6 kW. With cooling water flowing at 3.8 l/min, the coil temperature only increases by 7 degrees Celsius under continuous operation.
description: 5 pages, 5 figures
Adaptive Mobile Positioning in WCDMA Networks
Creators: name: Dong, B
name: Wang, Xiaodong
Publisher: name: Columbia University
Year: 2005
Subjects: Broadband communication systems
Mobile device forensics
Electrical engineering

description: We propose a new technique for mobile tracking in wideband code-division multiple-access (WCDMA) systems employing multiple receive antennas. To achieve a high estimation accuracy, the algorithm utilizes the time difference of arrival (TDOA) measurements in the forward link pilot channel, the angle of arrival (AOA) measurements in the reverse-link pilot channel, as well as the received signal strength. The mobility dynamic is modelled by a first-order autoregressive (AR) vector process with an additional discrete state variable as the motion offset, which evolves according to a discrete-time Markov chain. It is assumed that the parameters in this model are unknown and must be jointly estimated by the tracking algorithm. By viewing a nonlinear dynamic system such as a jump-Markov model, we develop an efficient auxiliary particle filtering algorithm to track both the discrete and continuous state variables of this system as well as the associated system parameters. Simulation results are provided to demonstrate the excellent performance of the proposed adaptive mobile positioning algorithm in WCDMA networks.
RTDK-BO: High Dimensional Bayesian Optimization with Reinforced Transformer Deep kernels
Creators: name: Shmakov, Alexander
name: Naug, Avisek
name: Gundecha, Vineet
name: Ghorbanpour, Sahand
name: Gutierrez, Ricardo Luna
name: Babu, Ashwin Ramesh
name: Guillen, Antonio
name: Sarkar, Soumyendu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Bayesian Optimization (BO), guided by Gaussian process (GP) surrogates, has proven to be an invaluable technique for efficient, high-dimensional, black-box optimization, a critical problem inherent to many applications such as industrial design and scientific computing. Recent contributions have introduced reinforcement learning (RL) to improve the optimization performance on both single function optimization and \textit{few-shot} multi-objective optimization. However, even few-shot techniques fail to exploit similarities shared between closely related objectives. In this paper, we combine recent developments in Deep Kernel Learning (DKL) and attention-based Transformer models to improve the modeling powers of GP surrogates with meta-learning. We propose a novel method for improving meta-learning BO surrogates by incorporating attention mechanisms into DKL, empowering the surrogates to adapt to contextual information gathered during the BO process. We combine this Transformer Deep Kernel with a learned acquisition function trained with continuous Soft Actor-Critic Reinforcement Learning to aid in exploration. This Reinforced Transformer Deep Kernel (RTDK-BO) approach yields state-of-the-art results in continuous high-dimensional optimization problems.
description: 2023 IEEE 19th International Conference on Automation Science and Engineering (CASE)
Slowly rotating black hole in chiral scalar-tensor theory
Creators: name: Yu, Ze-Kai
name: Liu, Lei
name: Zhu, Tao
Publisher: name: arXiv
Year: 2025
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The chiral scalar-tensor theory is an extension of the Chern-Simons modified gravity by introducing couplings between the first and second derivatives of the scalar field and parity-violating spacetime curvatures. A key feature of this theory is its explicit breaking of parity symmetry in the gravitational sector, which is expected to affect the spatial-time component of axisymmetric spacetime. In this paper, we investigate the effects of the chiral scalar-tensor theory on slowly rotating black holes by building on known solutions in the dynamical Chern-Simons modified gravity. Using perturbative methods with small coupling and slow rotation approximations, we find that the contributions of the chiral scalar-tensor theory appear at quadratic order in the spin and cubic order in the coupling constants. Furthermore, we explore the properties of this solution in the weak field and check its ergosphere and horizon. In the weak limit, we find that the effects of parity violation are suppressed in the weak field but could become significant in the strong field regime. These results provide insights into the behavior of parity-violating gravity in the presence of rotation and may be used for further investigations into its observational signatures.
description: 13 pages
A Cross-sectional Study of the Impact of Blood Selenium on Blood and Urinary Arsenic Concentrations in Bangladesh
Creators: name: George, Christine
name: Gamble, Mary
name: Slavkovich, Vesna N.
name: Levy, Diane
name: Ahmed, Alauddin
name: Ahsan, Habibul
name: Graziano, Joseph
Publisher: name: Columbia University
Year: 2013
Subjects: Environmental health
Epidemiology
Drinking water--Arsenic content
Arsenic--Metabolism
Selenium--Physiological effect

description: Background: Arsenic can naturally occur in the groundwater without an anthropogenic source of contamination. In Bangladesh over 50 million people are exposed to naturally occurring arsenic concentrations exceeding the World Health Organization’s guideline of 10 μg/L. Selenium and arsenic have been shown to facilitate the excretion of each other in bile. Recent evidence suggests that selenium may play a role in arsenic elimination by forming a selenium-arsenic conjugate in the liver before excretion into the bile. Methods: A cross-sectional study of 1601 adults and 287 children was conducted to assess the relationship between blood selenium and urinary and blood arsenic in a study population residing in a moderately arsenic-contaminated rural area in Bangladesh. Results: The results of this study indicate a statistically significant inverse relationship between blood selenium and urinary arsenic concentrations in both adult and pediatric populations in rural Bangladesh after adjustment for age, sex, Body Mass Index, plasma folate and B12 (in children), and ever smoking and current betel nut use (in adults). In addition, there appears to be a statistically significant inverse relationship between blood selenium and blood arsenic in children. Conclusions: Our results suggest that selenium is inversely associated with biomarkers of arsenic burden in both adults and children. These findings support the hypothesis that Se facilitates the biliary elimination of As, possibly via the putative formation of a Se-As conjugate using a glutathione complex. However, laboratory based studies are needed to provide further evidence to elucidate the presence of Se-As conjugate and its role in arsenic elimination in humans.
Efficient description of strongly correlated electrons with mean-field cost
Creators: name: Boguslawski, Katharina
name: Tecmer, Paweł
name: Ayers, Paul W.
name: Bultinck, Patrick
name: De Baerdemacker, Stijn
name: Van Neck, Dimitri
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We present an efficient approach to the electron correlation problem that is well-suited for strongly interacting many-body systems, but requires only mean-field-like computational cost. %which is based on orbital optimization of electron pairs. The performance of our approach is illustrated for the one-dimensional Hubbard model with periodic boundary conditions for different chain lengths, and for the non-relativistic quantum chemical Hamiltonian exploring the symmetric dissociation of the H$_{50}$ hydrogen chain.
description: 4 pages, 4 figures
Additional file 1 of Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas
Creators: name: Casanova, Nancy G.
name: Gonzalez-Garay, Manuel L.
name: Sun, Belinda
name: Bime, Christian
name: Xiaoguang Sun
name: Knox, Kenneth S.
name: Crouser, Elliott D.
name: Sammani, Nora
name: Gonzales, Taylor
name: Natt, Bhupinder
name: Chaudhary, Sachin
name: Lussier, Yves
name: Garcia, Joe G. N.
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Oncopanel gene list. List of the complete biomarker panel genes and the biological pathways assayed.
Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: an IVUS-based fluid-structure interaction multi-patient study
Creators: name: Fan, Rui
name: Tang, Dalin
name: Yang, Chun
name: Zheng, Jie
name: Bach, Richard
name: Wang, Liang
name: Muccigrosso, David
name: Billiar, Kristen
name: Zhu, Jian
name: Ma, Genshan
name: Maehara, Akiko
name: Mintz, Gary
Publisher: name: Columbia University
Year: 2014
Subjects: Intravascular ultrasonagraphy
Atherosclerotic plaque
Medicine

description: Background: Atherosclerotic plaque progression and rupture are believed to be associated with mechanical stress conditions. In this paper, patient-specific in vivo intravascular ultrasound (IVUS) coronary plaque image data were used to construct computational models with fluid-structure interaction (FSI) and cyclic bending to investigate correlations between plaque wall thickness and both flow shear stress and plaque wall stress conditions. Methods: IVUS data were acquired from 10 patients after voluntary informed consent. The X-ray angiogram was obtained prior to the pullback of the IVUS catheter to determine the location of the coronary artery stenosis, vessel curvature and cardiac motion. Cyclic bending was specified in the model representing the effect by heart contraction. 3D anisotropic FSI models were constructed and solved to obtain flow shear stress (FSS) and plaque wall stress (PWS) values. FSS and PWS values were obtained for statistical analysis. Correlations with p
Spatiality of derivations on the algebra of $τ$-compact operators
Creators: name: Ayupov, Shavkat
name: Kudaybergenov, Karimbergen
Publisher: name: arXiv
Year: 2013
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 47B47

description: This paper is devoted to derivations on the algebra $S_0(M, τ)$ of all $τ$-compact operators affiliated with a von Neumann algebra $M$ and a faithful normal semi-finite trace $τ.$ The main result asserts that every $t_τ$-continuous derivation $D:S_0(M, τ)\rightarrow S_0(M, τ)$ is spatial and implemented by a $τ$-measurable operator affiliated with $M$, where $t_τ$ denotes the measure topology on $S_0(M, τ)$. We also show the automatic $t_τ$-continuity of all derivations on $S_0(M, τ)$ for properly infinite von Neumann algebras $M$. Thus in the properly infinite case the condition of $t_τ$-continuity of the derivation is redundant for its spatiality.
description: 15 pages. arXiv admin note: substantial text overlap with arXiv:1306.0251
Vitamin D resistance in chronic kidney disease (CKD)
Creators: name: Parikh, Amay
name: Chase Jr, Herbert
name: Vernocchi, Linda
name: Stern, Leonard
Publisher: name: Columbia University
Year: 2014
Subjects: Cholecalciferol
Kidneys--Diseases--Treatment
Medicine

description: Background: Previous studies have shown that treatment with ergocalciferol in patients with CKD stage 3 + 4 is not effective with less than 33% of patients achieving a 25-OH vitamin D target of >30 ng/ml. The aim of this study was to test the response to cholecalciferol in CKD. We attempted to replete 25-OH vitamin D to a target level of 40–60 ng/ml using the response to treatment and PTH suppression as an outcome measure. Methods: This retrospective cohort study identified patients (Stages 2–5 and Transplant) from 2001–2010 who registered at the Chronic Kidney Disease Clinic. Patients received cholecalciferol 10,000 IU capsules weekly as initial therapy. When levels above 40 ng/ml were not achieved, doses were titrated up to a maximum of 50,000 IU weekly. Active vitamin D analogs were also used in some Stage 4–5 CKD patients per practice guidelines. Patients reaching at least one level of 40 ng/mL were designated RESPONDER, and if no level above 40 ng/mL they were designated NON-RESPONDER. Patients were followed for at least 6 months and up to 5 years. Results: 352 patients were included with a mean follow up of 2.4 years. Of the CKD patients, the initial 25-OH vitamin D in the NON-RESPONDER group was lower than the RESPONDER group (18 vs. 23 ng/ml) (p = 0.03). Among all patients, the initial eGFR in the RESPONDER group was significantly higher than the NON-RESPONDER group (36 vs. 30 ml/min/1.73 m2) (p < 0.001). Over time, the eGFR of the RESPONDER group stabilized or increased (p < 0.001). Over time, the eGFR in the NON-RESPONDER group decreased toward a trajectory of ESRD. Proteinuria did not impact the response to 25-OH vitamin D replacement therapy. There were no identifiable variables associated with the response or lack of response to cholecalciferol treatment. Conclusions: CKD patients treated with cholecalciferol experience treatment resistance in raising vitamin D levels to a pre-selected target level. The mechanism of vitamin D resistance remains unknown and is associated with progressive loss of eGFR. Proteinuria modifies but does not account for the vitamin D resistance.