cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Developmental dysplasia of the hip (DDH) - review of major imaging techniques
Creators: name: Martin, Alexandra
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Musculoskeletal joint
subject: Paediatric
subject: Ultrasound
subject: Digital radiography
subject: MR
subject: Education
subject: Developmental disease

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review DDH’s multimodality image algorithm used for diagnosis and follow-up, due to the fact that early diagnosis is important to institute appropriate treatment and reduce the incidence of long- term...
title: Hippocampus Hitched - exemplifying the anatomy and pathology, a pictorial essay
Creators: name: Patwari, Sriram
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR
subject: Imaging sequences
subject: Pathology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The objectives of this poster is to: To comprehend the hippocampal anatomy To review the primary and secondary pathologies of...
title: Abdominal manifestations of Polysplenia syndrom in adults : What radiologists need to know
Creators: name: Garrouche, Nada
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Education and training
subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: CT
subject: Pancreas
subject: Anatomy
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1)To explain the spectrum of situs anomalies (situs solitus, situs inversus and situs ambiguous) 2)To precise the critical structures to be evaluted in imaging in determining situs 3)To illustrate the typical anatomic findings in classical...
Effects of Provisional Cements on Shear Bond Strength of Resin Cements to Dentin
Creators: name: Banthitkhunanon, Pattaranat
Publisher: name: The Dental Association of Thailand
Year: 2019
Subjects: Provisional cement
Resin cement
Shear bond strength (SBS)

description: Journal of The Dental Association of Thailand, 69, Supplement Issue, 038-046
Efficacy of Double Antibiotics in Hydroxypropyl Methylcellulose Gel against Enterococcus faecalis in Root Canals: An in vitro Study
Creators: name: Kundacha, Praman
Publisher: name: The Dental Association of Thailand
Year: 2019
Subjects: Biodegradable gel
Double antibiotics
Enterococcus faecalis
Intracanal medication
Root canal treatment

description: Journal of The Dental Association of Thailand, 69, Supplement Issue, 047-057
Population transfer in a Lambda system induced by detunings
Creators: name: Di Stefano, P. G.
name: Paladino, E.
name: D'Arrigo, A.
name: Falci, G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In this paper we propose a new protocol to achieve coherent population transfer between two states in a three-level atom by using two ac fields. It is based on the physics of Stimulated Raman Adiabatic Passage (STIRAP), but it is implemented with the constraint of a reduced control, namely one of the fields cannot be switched off. A combination of frequency chirps is used with resonant fields, allowing to achieve approximate destructive interference, despite of the fact that an exact dark state does not exist. This new chirped STIRAP protocol is tailored for applications to artificial atoms, where architectures with several elementary units can be strongly coupled but where the possibility of switching on and off such couplings is often very limited. Demonstration of this protocol would be a benchmark for the implementation of a class of multilevel advanced control procedures for quantum computation and microwave quantum photonics in artificial atoms.
description: 9 pages, 6 figures
(101402) Claude James Maish
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: The Variety and Quality of Mobile Device Applications in Neuroradiology
Creators: name: Lynch, Jeremy
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neuroradiology brain
subject: Neuroradiology spine
subject: Computer applications
subject: Teleradiology
subject: Technology assessment
subject: Computer Applications-General
subject: Computer Applications-Detection, diagnosis
subject: Education and training

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Obtain a perspective on the availability of mobile applications (“apps”) developed specifically for diagnostic and interventionalneuroradiology Appraise the variety and quality of these applications including whether there was healthcare...
Glucose-responsive oral insulin delivery for postprandial glycemic regulation
Creators: name: Wen, D.
name: Buse, J.B.
name: Zhang, Y.
name: Kahkoska, A.R.
name: Wang, J.
name: Yu, J.
name: Gu, Z.
Publisher: name: Tsinghua University Press
Year: 2019

description: Controlling postprandial glucose levels for diabetic patients is critical to achieve the tight glycemic control that decreases the risk for developing long-term micro- and macrovascular complications. Herein, we report a glucose-responsive oral insulin delivery system based on Fc receptor (FcRn)-targeted liposomes with glucose-sensitive hyaluronic acid (HA) shell for postprandial glycemic regulation. After oral administration, the HA shell can quickly detach in the presence of increasing intestinal glucose concentration due to the competitive binding of glucose with the phenylboronic acid groups conjugated with HA. The exposed Fc groups on the surface of liposomes then facilitate enhanced intestinal absorption in an FcRn-mediated transport pathway. In vivo studies on chemically-induced type 1 diabetic mice show this oral glucose-responsive delivery approach can effectively reduce postprandial blood glucose excursions. This work is the first demonstration of an oral insulin delivery system directly triggered by increasing postprandial glucose concentrations in the intestine to provide an on-demand insulin release with ease of administration.
Targeting hepatic glucokinase to treat diabetes with TTP399, a hepatoselective glucokinase activator
Creators: name: Dunn, I.
name: Keller, K.
name: Freeman, J.L.R.
name: Buse, J.B.
name: Vella, A.
name: Valcarce, C.
Publisher: name: American Association for the Advancement of Science
Year: 2019

description: The therapeutic success of interventions targeting glucokinase (GK) activation for the treatment of type 2 diabetes has been limited by hypoglycemia, steatohepatitis, and loss of efficacy over time. The clinical characteristics of patients with GK-activating mutations or GK regulatory protein (GKRP) loss-of-function mutations suggest that a hepatoselective GK activator (GKA) that does not activate GK in cells or affect the GK-GKRP interaction may reduce hyperglycemia in patients with type 2 diabetes while limiting hypoglycemia and liver-associated adverse effects. Here, we review the rationale for TTP399, an oral hepatoselective GKA, and its progression from preclinical to clinical development, with an emphasis on the results of a randomized, double-blind, placebo- and active-controlled phase 2 study of TTP399 in patients with type 2 diabetes. In this 6-month study, TTP399 (800 mg/day) was associated with a clinically significant and sustained reduction in glycated hemoglobin, with a placebo-subtracted least squares mean HbA 1c change from baseline of −0.9% (P < 0.01). Compared to placebo, TTP399 (800 mg/day) also increased high-density lipoprotein cholesterol (3.2 mg/dl; P < 0.05), decreased fasting plasma glucagon (−20 pg/ml; P < 0.05), and decreased weight in patients weighing ≥100 kg (−3.4 kg; P < 0.05). TTP399 did not cause hypoglycemia, had no detrimental effect on plasma lipids or liver enzymes, and did not increase blood pressure, highlighting the importance of tissue selectivity and preservation of physiological regulation when targeting key metabolic regulators such as GK.
The effect of tricuspid annuloplasty ring shape and size on tricuspid valve repair
Creators: name: Haese, Collin E.
name: 0009-0005-0561-2545
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Tricuspid repair annuloplasty

description: A leaking tricuspid valve affects nearly 1.6 million Americans which carries high rates of morbidity and mortality. Unfortunately, existing valve repair strategies are suboptimal with up to 30% of patients exhibiting recurrent regurgitation following intervention. Computer models offer a valuable tool to better understand the tricuspid valve and work towards better surgical outcomes. To this end, we previously developed a high-fidelity patient-specific finite element model of the human tricuspid valve. In addition to faithfully capturing the kinetics and kinematics of the healthy valve, it can also simulate disease progression by mirroring functional tricuspid regurgitation. In this work, we virtually repair the diseased valve using 24 different rigid annuloplasty rings. After simultaneously simulating the repair procedure, we report clinical and mechanical measures to offer insight in to the advantages and disadvantages of each ring. We show ring size and shape play a significant role in predicting the post-repair mechanical outcome of the valve. That is, the measures differ after implanting contoured and flat rings. Interestingly, stress in the anterior leaflet appears to be invariant to the choice of ring size or shape. For this specific valve, excessive undersizing did not appear to negatively impact immediate post-repair outcomes. Importantly, this study highlights the significance of proper ring choice and hopes to spur further study and development of proper sizing strategies. Additionally, our model and data are openly available and will hopefully allow for further virtual experiments to better understand and optimize tricuspid valve repair for improved patient outcomes.
Clinical Outcomes in Patients with Type 2 Diabetes Mellitus and Peripheral Artery Disease: Results from the EXSCEL Trial
Creators: name: Goodman, S.G.
name: Sattar, N.
name: Katona, B.
name: Patel, M.R.
name: Buse, J.B.
name: Mentz, R.J.
name: Jones, S.W.
name: Badjatiya, A.
name: Merrill, P.
name: Hernandez, A.F.
name: Holman, R.R.
name: Pagidipati, N.J.
name: Iqbal, N.
Publisher: name: Lippincott Williams and Wilkins
Year: 2019

description: Background: Recent trials have identified anti-diabetes mellitus agents that lower major adverse cardiovascular event (MACE) rates, although some increase rates of lower-extremity amputation (LEA). Patients with peripheral artery disease (PAD) have greater incidence of diabetes mellitus and risk for LEA, prompting this investigation of clinical outcomes in patients with diabetes mellitus and PAD in the EXSCEL trial (Exenatide Study of Cardiovascular Event Lowering). Methods: EXSCEL evaluated the effects of once-weekly exenatide (a GLP-1 [glucagon-like peptide-1] receptor agonist) versus placebo on the rates of the primary composite MACE end point (cardiovascular death, myocardial infarction, or stroke) among patients with type 2 diabetes mellitus. In this post hoc analysis, we assessed the association of baseline PAD with rates of MACE, LEA, and the effects of exenatide versus placebo in patients with and without PAD. Results: EXSCEL included 2800 patients with PAD (19% of the trial population). These individuals had higher unadjusted and adjusted rates of MACE compared with patients without PAD (13.6% versus 11.4%, respectively) as well as a higher adjusted hazard ratio (adjusted hazard ratio, 1.13 [95% CI, 1.00-1.27]; P=0.047). Patients with PAD had higher all-cause mortality (adjusted hazard ratio 1.38 [95% CI, 1.20-1.60]; P<0.001) and more frequent LEA (adjusted hazard ratio 5.48 [95% CI, 4.16-7.22]; P<0.001). Patients treated with exenatide or placebo had similar rates of MACE and LEA, regardless of PAD status. Conclusions: EXSCEL participants with PAD had higher rates of all-cause mortality and LEA compared with those without PAD. There were no differences in MACE or LEA rates with exenatide versus placebo. Clinical Trial Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT01144338.
Sweet Difference Threshold of Strawberry-Flavored Carbonated Drink in 8-Year-Old Children in Khon Kaen
Creators: name: Paphangkorakit, Jarin
Publisher: name: The Dental Association of Thailand
Year: 2019
Subjects: Carbonated drink
Difference threshold
Sugar consumption
Sugar reduction

description: Journal of The Dental Association of Thailand, 69, Supplement Issue, 068-074
title: Cardiac imaging findings in stroke patients: what radiologists need to know.
Creators: name: Zuccarino, Flavio
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Ischaemia / Infarction
subject: Diagnostic procedure
subject: MR
subject: CT
subject: Neuroradiology brain
subject: Cardiovascular system
subject: Cardiac

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe CT and MRI cardiac imaging findings that might be cause of stroke. To identify subtle cardiac findings in angiographic-CT study usually performed in initial diagnosis of stroke. To perform a proper differential diagnosis in order to...
(101399) Elizabeth Maish
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Trajectory patterns of ethnic identity among Mexican-origin female adults : the role of age of arrival to the U.S.
Creators: name: Tse, Hin Wing
name: 0000-0003-2781-1279
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Trajectory patterns
Ethnic identity
Exploration
Resolution
Centrality
Mexican-origin
Adulthood

description: Extant research on ethnic identity have primarily focused on adolescence, overlooking the development of ethnic identity in adulthood, which is a critical gap in the literature from a lifespan perspective. Additionally, past research has shown that age of arrival to a host country may determine the overall exposure to sociocultural contexts, which could trigger a variation of trajectory patterns in ethnic identity at later stage of life (e.g., during adulthood). Using a three-wave longitudinal dataset of 596 Mexican-born female adults, three independent growth mixture models were estimated to identify variation in trajectory patterns of ethnic identity exploration, resolution, and centrality. Two distinct trajectories were found in each component of ethnic identity. Associations between linear/quadratic effect of age of arrival to the U.S. and trajectory patterns of ethnic identity exploration, resolution, and centrality were examined, controlling for demographics, including age, income, and education at Wave 1. Results indicated that age of arrival to the U.S. (linear and quadratic terms) were not significant predictors of trajectory patterns of ethnic identity. Study findings add to our understanding of the contemporary lifespan model of ethnic identity development and show that ethnic identity continues to evolve beyond young adulthood. This study may also provide insights for future research on how different trajectory patterns of individual ethnic identity component may be linked to psychological and sociocultural adaptation outcomes in adult immigrant populations.
title: Tendons: normal anatomy and ultrasound assessment of most frequent pathology
Creators: name: Vasilevska Nikodinovska, Violeta
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Athletic injuries
subject: Arthritides
subject: Acute
subject: Education
subject: Diagnostic procedure
subject: Ultrasound-Spectral Doppler
subject: Ultrasound
subject: Trauma
subject: Musculoskeletal soft tissue
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To explain the normal ultrasound anatomy of the tendons To emphasize the importance and possibilities of the high-resolution ultrasound in diagnosis of pathology of the tendons To show the most common pathology of tendons of upper and lower...
(101395) Michael Mahony
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Effects of exenatide and open-label SGLT2 inhibitor treatment, given in parallel or sequentially, on mortality and cardiovascular and renal outcomes in type 2 diabetes: Insights from the EXSCEL trial
Creators: name: Clegg, L.E.
name: Penland, R.C.
name: Bachina, S.
name: Ruggles, J.A.
name: Buse, J.B.
name: Holman, R.R.
name: Mentz, R.J.
name: Heerspink, H.J.L.
name: Gustavson, S.
name: Hernandez, A.F.
name: Thuresson, M.
name: Sjöström, C.D.
name: Boulton, D.W.
Publisher: name: BioMed Central Ltd.
Year: 2019

description: Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RA) improve cardiovascular and renal outcomes in patients with type 2 diabetes through distinct mechanisms. However, evidence on clinical outcomes in patients treated with both GLP-1 RA and SGLT2i is lacking. We aim to provide insight into the effects of open-label SGLT2i use in parallel with or shortly after once-weekly GLP-1 RA exenatide (EQW) on cardiorenal outcomes. Methods: In the EXSCEL cardiovascular outcomes trial EQW arm, SGLT2i drop-in occurred in 8.7% of participants. These EQW+SGLT2i users were propensity-matched to: (1) placebo-arm participants not taking SGLT2i (n = 572 per group); and to (2) EQW-arm participants not taking SGLT2i (n = 575), based on their last measured characteristics before SGLT2i initiation, and equivalent study visit in comparator groups. Time-to-first major adverse cardiovascular event (MACE) and all-cause mortality (ACM) were compared using Cox regression analyses. eGFR slopes were quantified using mixed model repeated measurement analyses. Results: In adjusted analyses, the risk for MACE with combination EQW+SGLT2i use was numerically lower compared with both placebo (adjusted hazard ratio 0.68, 95% CI 0.39-1.17) and EQW alone (0.85, 0.48-1.49). Risk of ACM was nominally significantly reduced compared with placebo (0.38, 0.16-0.90) and compared with EQW (0.41, 0.17-0.95). Combination EQW+SGLT2i use also nominally significantly improved estimated eGFR slope compared with placebo (+ 1.94, 95% CI 0.94-2.94 mL/min/1.73 m2/year) and EQW alone (+ 2.38, 1.40-3.35 mL/min/1.73 m2/year). Conclusions: This post hoc analysis supports the hypothesis that combinatorial EQW and SGLT2i therapy may provide benefit on cardiovascular outcomes and mortality. Trial registration Clinicaltrials.gov, Identifying number: NCT01144338, Date of registration: June 15, 2010.
(101397) Ellen Cox
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Imaging strategies for uncooperative patients
Creators: name: Cruz, João
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Technical aspects
subject: Imaging sequences
subject: MR
subject: Abdomen
subject: Education and training
subject: Quality assurance

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: · To understand the importance of different motion-resistant magnetic resonance (MR) sequences on imaging uncooperative patients, especially those who can't suspend respiration. ·Get familiar with different types of abdominal motion-resistant MR...
Long-term efficacy and safety of combined insulin and glucagon-like peptide-1 therapy: Evidence from the LEADER trial
Creators: name: Nauck, M.A.
name: Poulter, N.R.
name: The LEADER Publication Committee on behalf of the LEADER Trial Investigators
name: Startseva, E.
name: Bosch-Traberg, H.
name: Desouza, C.
name: Buse, J.B.
name: Jacob, S.
name: Petrie, J.R.
name: Tack, C.J.
name: Zinman, B.
name: Stegmann, H.V.B.K.
name: Pratley, R.E.
name: Bain, S.C.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aim: Glucagon-like peptide-1 receptor agonist (GLP-1RA) and insulin combination therapy is an effective treatment option for type 2 diabetes, but long-term data are lacking. The aim was to assess the long-term efficacy of the GLP-1RA liraglutide in subgroups by insulin use in the LEADER trial. Materials and Methods: LEADER assessed cardiovascular (CV) safety and efficacy of liraglutide (1.8 mg) versus placebo (plus standard of care therapy) in 9340 patients with type 2 diabetes and high risk of CV disease, for up to 5 years. We analyzed CV events, metabolic parameters and hypoglycaemia post hoc in three subgroups by baseline insulin use (basal-only insulin, other insulin or no insulin). Insulin was a non-random treatment allocation as part of standard of care therapy. Results: At baseline, 5171 (55%) patients were not receiving insulin, 3159 (34%) were receiving basal-only insulin and 1010 (11%) other insulins. Insulin users had a longer diabetes duration and slightly worse glycaemic control (HbA1c) than the no-insulin subgroup. Liraglutide reduced HbA1c and weight versus placebo in all three subgroups (P <.001), and severe hypoglycaemia rate in the basal-only insulin subgroup. The need for insulin was less with liraglutide. CV risk reduction with liraglutide was similar to the main trial results in the basal-only and no-insulin subgroups. Conclusions: In patients on insulin, liraglutide improved glycaemic control, weight and need for insulin versus placebo, for at least 36 months with no increased risk of severe hypoglycaemia, while maintaining CV safety/efficacy, supporting the combination of liraglutide and insulin for management of type 2 diabetes.
Phase-Noise Mitigation in OFDM by Best Match Trajectories
Creators: name: Negusse, Senay
name: Zetterberg, Per
name: Händel, Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: This paper proposes a novel approach to phase-noise compensation. The basic idea is to approximate the phase-noise statistics by a finite number of realizations, i.e., a phase-noise codebook. The receiver then uses an augmented received signal model, where the codebook index is estimated along with other parameters. The realization of the basic idea depends on the details of the air interface, the phase-noise statistics, the propagation scenario and the computational constraints. In this paper, we will focus on a MQAM-OFDM system with pilot sub-carriers within each OFDM symbol. The channel is frequency selective, fading and unknown. A decision-feedback method is employed to further enhance performance of the system. Simulation results are shown for uncoded and coded systems to illustrate the performance of the algorithm, which is also compared with previously employed methods. Our simulations show that for a 16-QAM coded OFDM system over a frequency selective Rayleigh fading channel affected by phase noise with root-mean-square (RMS) of 14.4 degrees per OFDM symbol, the proposed algorithm is 1.5dB from the ideal phase-noise free case at a BER of $10^{-4}$. The performance of the best reference scheme is 2.5dB from the ideal case at BER of $10^{-4}$. The proposed scheme is also computationally attractive.
description: Accepted for publication in IEEE Transactions on Communications, 2015
On Gauge Enhancement and Singular Limits in $G_2$ Compactifications of M-theory
Creators: name: Halverson, James
name: Morrison, David R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the physics of singular limits of $G_2$ compactifications of M-theory, which are necessary to obtain a compactification with non-abelian gauge symmetry or massless charged particles. This is more difficult than for Calabi-Yau compactifications, due to the absence of calibrated two-cycles that would have allowed for direct control of W-boson masses as a function of moduli. Instead, we study the relationship between gauge enhancement and singular limits in $G_2$ moduli space where an associative or coassociative submanifold shrinks to zero size; this involves the physics of topological defects and sometimes gives indirect control over particle masses, even though they are not BPS. We show how a lemma of Joyce associates the class of a three-cycle to any $U(1)$ gauge theory in a smooth $G_2$ compactification. If there is an appropriate associative submanifold in this class then in the limit of nonabelian gauge symmetry it may be interpreted as a gauge theory worldvolume and provides the location of the singularities associated with non-abelian gauge or matter fields. We identify a number of gauge enhancement scenarios related to calibrated submanifolds, including Coulomb branches and non-isolated conifolds, and also study examples that realize them.
description: 41 pages plus references and appendices. v2: references added. v3: JHEP version
title: Response to the ten most frequently asked questions about use of contrast in ultrasonography in liver
Creators: name: Moalla, Salma
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Ultrasound physics
subject: Liver
subject: Contrast agents
subject: Ultrasound
subject: Diagnostic procedure
subject: Tissue characterisation
subject: Multidisciplinary cancer care

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Know the basis of contrast enhanced ultrasound (CEUS): technique, echocontrast agent, tricks and trucks in common practice Know the aspect of the most commonly found lesion in the liver Know the practical application of...
Broadband laser polarization control with aligned carbon nanotubes
Creators: name: Yang, He
name: Fua, Bo
name: Lia, Diao
name: Chen, Ya
name: Mattila, Marco
name: Tian, Ying
name: Yong, Zhenzhong
name: Yang, Changxi
name: Tittonen, Ilkka
name: Ren, Zhaoyu
name: Bai, Jingtao
name: Li, Qingwen
name: Kauppinen, Esko I.
name: Lipsanen, Harri
name: Sun, Zhipei
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We introduce a simple approach to fabricate aligned carbon nanotube (ACNT) device for broadband polarization control in fiber laser systems. The ACNT device was fabricated by pulling from as-fabricated vertically-aligned carbon nanotube arrays. Their anisotropic property is confirmed with optical and scanning electron microscopy, and with polarized Raman and absorption spectroscopy. The device was then integrated into fiber laser systems (at two technologically important wavelengths of 1 and 1.5 um) for polarization control. We obtained a linearly-polarized light output with the maximum extinction ratio of ~12 dB. The output polarization direction could be fully controlled by the ACNT alignment direction in both lasers. To the best of our knowledge, this is the first time that ACNT device is applied to polarization control in laser systems. Our results exhibit that the ACNT device is a simple, low-cost, and broadband polarizer to control laser polarization dynamics, for various photonic applications (such as material processing, polarization diversity detection in communications), where the linear polarization control is necessary.
description: 5 pages, 6 figures
Incorporating and interpreting regulatory guidance on estimands in diabetes clinical trials: The PIONEER 1 randomized clinical trial as an example
Creators: name: Donsmark, M.
name: Aroda, V.R.
name: Buse, J.B.
name: Saugstrup, T.
name: Davies, M.J.
name: Zacho, J.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Regulatory guidelines describe the use of estimands in designing and conducting clinical trials. Estimands ensure alignment of the objectives with the design, conduct and analysis of a trial. An estimand is defined by four inter-related attributes: the population of interest, the variable (endpoint) of interest, the way intercurrent events are handled and the population level summary. A trial may employ multiple estimands to evaluate treatment effects from different perspectives in order to address different scientific questions. As estimands may be an unfamiliar concept for many clinicians treating diabetes, this paper reviews the estimand concept and uses the PIONEER 1 phase 3a clinical trial, which investigated the efficacy and safety of oral semaglutide vs placebo, as an example of the way in which estimands can be implemented and interpreted. In the PIONEER 1 trial, two estimands were employed for each efficacy endpoint and were labelled as: (a) the treatment policy estimand, used to assess the treatment effect regardless of use of rescue medication or discontinuation of trial product, and provides a broad perspective of the treatment effect in the population of patients with type 2 diabetes in clinical practice
description: and (b) the trial product estimand, used to assess the treatment effect if all patients had continued to use trial product for the planned duration of the trial without rescue medication, thereby providing information on the anticipated treatment effect of the medication. Both approaches are complementary to understanding the effect of the studied treatments.
(101393) Ellen Mahony
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: A step-by-step diagnostic algorithm of bone tumors and pseudo-tumors
Creators: name: Iacoban, Cătălin
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neoplasia
subject: Education
subject: MR
subject: CT
subject: Conventional radiography
subject: Musculoskeletal bone

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Review and reinforcement of the diagnostic algorythm of bone tumors and pseudo-tumors. 2. Appropriate discrimination of benign versus malignant bone entities via a radiographic checklist . 3. Assessment of the benefits of...
Optimal designs for estimating individual coefficients in polynomial regression with no intercept
Creators: name: Dette, Holger
name: Melas, Viatcheslav B.
name: Shpilev, Petr
Publisher: name: Technische Universität Dortmund
Year: 2019
Subjects: subject: polynomial regression
subject: c-optimal design
subject: Chebyshev system
subject: 310
subject: 330
subject: 620

description: In a seminal paper Studden (1968) characterized c-optimal designs in regression models, where the regression functions form a Chebyshev system. He used these results to determine the optimal design for estimating the individual coefficients in a polynomial regression model on the interval [-1; 1] explicitly. In this note we identify the optimal design for estimating the individual coefficients in a polynomial regression model with no intercept (here the regression functions do not form a Chebyshev system).
description: Discussion Paper / SFB823;13/2019
title: Knowing CADASIL. MRI findings in a rare disease
Creators: name: Roig Egea, Paula
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Ischaemia / Infarction
subject: Dementia
subject: Diagnostic procedure
subject: Neural networks
subject: Neuroradiology brain

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe the characteristic magnetic resonance (MRI) and CT patterns in patients with diagnosis of Cerebral Autosomal Dominant Arteriopathy with sub-cortical infarcts and leukoencephalopathy...
Analysis of internal material loads and Process Signature Components in deep rolling
Creators: name: Kinner-Becker, Tobias
name: Hettig, Matthias-Alexander
name: Sölter, Jens
name: Meyer, Daniel
Publisher: name: Elsevier
Year: 2021
Subjects: subject: Finite element method (FEM)
subject: Simulation
subject: Deep Rolling
subject: Surface modification
subject: Process Signature
subject: Residual stress
subject: 620

description: The high mechanical loads in deep rolling lead to a beneficial surface topography, hardness alterations, and compressive residual stresses. The generation of defined residual stress values has been achieved in a mainly iterative way, as the relevant internal material loads occurring during the process could not be considered. They are difficult to determine experimentally and well-validated models are required to deduce them e.g. from finite element (FE) simulations. In this study, a 3D FE model has been developed to analyze the strains in the workpiece material as a measure for the internal material load during the process. The residual stress profiles were measured by x-ray-diffraction and are presented in a way that allows for deriving the internal material loads required to induce a desired residual stress state.
Tailoring the nature and strength of electron-phonon interactions in the SrTiO$_3$(001) two-dimensional electron liquid
Creators: name: Wang, Z.
name: Walker, S. McKeown
name: Tamai, A.
name: Wang, Y.
name: Ristic, Z.
name: Bruno, F. Y.
name: de la Torre, A.
name: Riccò, S.
name: Plumb, N. C.
name: Shi, M.
name: Hlawenka, P.
name: Sánchez-Barriga, J.
name: Varykhalov, A.
name: Kim, T. K.
name: Hoesch, M.
name: King, P. D. C.
name: Meevasana, W.
name: Diebold, U.
name: Mesot, J.
name: Moritz, B.
name: Devereaux, T. P.
name: Radovic, M.
name: Baumberger, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Surfaces and interfaces offer new possibilities for tailoring the many-body interactions that dominate the electrical and thermal properties of transition metal oxides. Here, we use the prototypical two-dimensional electron liquid (2DEL) at the SrTiO$_3$(001) surface to reveal a remarkably complex evolution of electron-phonon coupling with the tunable carrier density of this system. At low density, where superconductivity is found in the analogous 2DEL at the LaAlO$_3$/SrTiO$_3$ interface, our angle-resolved photoemission data show replica bands separated by 100\,meV from the main bands. This is a hallmark of a coherent polaronic liquid and implies strong long-range coupling to a single longitudinal optical phonon mode. In the overdoped regime the preferential coupling to this mode decreases and the 2DEL undergoes a crossover to a more conventional metallic state with weaker short-range electron-phonon interaction. These results place constraints on the theoretical description of superconductivity and allow for a unified understanding of the transport properties in SrTiO$_3$-based 2DELs.
(101396) Edward Maish
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Duration of diabetes and cardiorenal efficacy of liraglutide and semaglutide: A post hoc analysis of the LEADER and SUSTAIN 6 clinical trials
Creators: name: Buse, J.B.
name: Zinman, B.
name: Bain, S.C.
name: Monk Fries, T.
name: Pratley, R.E.
name: Verma, S.
name: Mazer, C.D.
name: Saevereid, H.A.
name: Rasmussen, S.
name: Nauck, M.A.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Cardiovascular risk reduction with liraglutide and semaglutide in patients with type 2 diabetes was demonstrated in the LEADER (ClinicalTrials.gov: NCT01179048) and SUSTAIN 6 (ClinicalTrials.gov: NCT01720446) cardiovascular outcome trials. This post hoc analysis assessed the impact of diabetes duration (<5, 5 to <15, 15 to <25 and ≥25 years at baseline) on cardiorenal efficacy of these human glucagon-like peptide-1 analogues using a Cox proportional hazards model. Proportions of patients in the LEADER trial across diabetes duration strata were 15% (<5 years, n = 1377), 50% (5 to <15 years, n = 4692), 27% (15 to <25 years, n = 2504) and 8% (≥25 years, n = 748); corresponding proportions in the SUSTAIN-6 trial were 13% (<5 years, n = 422), 48% (5 to <15 years, n = 1582), 30% (15 to <25 years, n = 977) and 10% (≥25 years, n = 316). Overall, longer diabetes duration was associated with higher age; higher prevalence of females; history of ischaemic stroke, peripheral arterial disease and insulin use; and inferior renal function. There was an increased frequency of major adverse cardiovascular events (MACE), expanded MACE and nephropathy events with increasing diabetes duration. Liraglutide and semaglutide consistently reduced the risk of cardiorenal outcomes across categories of diabetes duration (P-interaction was not significant for all endpoints analysed).
title: Review of imaging and outcome of nodules followed up at a virtual lung nodule clinic
Creators: name: Hawthorne, James
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Respiratory system
subject: Lung
subject: Oncology
subject: CT
subject: Outcomes analysis
subject: Outcomes

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Pulmonary nodules are well or poorly circumscribed, nearly rounded structures that appear on imaging as focal opacities and are < 3cm in diameter and surrounded by aerated lung. Pulmonary nodules are commonly detected in clinical practice. Nodules...
Cardiovascular safety and lower severe hypoglycaemia of insulin degludec versus insulin glargine U100 in patients with type 2 diabetes aged 65 years or older: Results from DEVOTE (DEVOTE 7)
Creators: name: Franek, E.
name: McGuire, D.K.
name: Hansen, C.T.
name: Zinman, B.
name: Marso, S.P.
name: DEVOTE Study Group
name: Mark, T.
name: Emerson, S.S.
name: Buse, J.B.
name: Gilbert, M.P.
name: Moses, A.C.
name: Pratley, R.E.
name: Pieber, T.R.
name: Hansen, M.V.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aims: The aim of this study was to describe the risks of cardiovascular (CV) events and severe hypoglycaemia with insulin degludec (degludec) vs insulin glargine 100 units/mL (glargine U100) in patients with type 2 diabetes (T2D) aged 65 years or older. Materials and methods: A total of 7637 patients in the DEVOTE trial, a treat-to-target, randomized, double-blind trial evaluating the CV safety of degludec vs glargine U100, were divided into three age groups (50-64 years, n = 3682; 65-74 years, n = 3136; ≥75 years, n = 819). Outcomes by overall age group and randomized treatment differences were analysed for major adverse cardiovascular events (MACE), all-cause mortality, severe hypoglycaemia and serious adverse events (SAEs). Results: Patients with increasing age had higher risks of CV death, all-cause mortality and SAEs, and there were non-significant trends towards higher risks of MACE and severe hypoglycaemia. Treatment effects on the risk of MACE, all-cause mortality, severe hypoglycaemia and SAEs were consistent across age groups, based on the non-significant interactions between treatment and age with regard to these outcomes. Conclusions: There were higher risks of CV death, all-cause mortality and SAEs, and trends towards higher risks of MACE and severe hypoglycaemia with increasing age after adjusting for baseline differences. The effects across age groups of degludec vs glargine U100 on MACE, all-cause mortality and severe hypoglycaemia were comparable, suggesting that the risk of MACE, as well as all-cause mortality, is similar and the risk of severe hypoglycaemia is lower with degludec regardless of age. Evidence is conclusive only until 74 years of age.
Production of ceramic membranes with different pore sizes for virus retention
Creators: name: Werner, Julia
name: Besser, Benjamin
name: Brandes, Christoph
name: Kroll, Stephen
name: Rezwan, Kurosch
Publisher: name: Elsevier
Year: 2014
Subjects: subject: Extrusion
subject: Ceramic capillary membrane
subject: Virus retention
subject: Porosity
subject: Pore size
subject: Mimenima
subject: 620

description: Abstract Porous ceramic capillary membranes made of yttria-stabilised zirconia (YSZ) are presented, which are conditioned for virus filtration by varying the initial YSZ particle size. Compared to polymeric membranes, ceramic membranes offer remarkable advantages for filtration processes as they show excellent chemical, thermal and mechanical stability and can easily be cleaned by backflushing. YSZ powders with different particle sizes (30 nm, 40 nm and 90 nm) are individually and mixed processed by extrusion, dried and finally sintered at 1050 °C for 2 h. The sintered YSZ capillaries are characterised by microstructural analysis including Hg-porosimetry, BET analysis and 3-point bending tests. By increasing the initial YSZ particle size, increased average membrane pore sizes ranging from 24 nm to 146 nm are obtained. Mechanically stable membranes are provided showing high open porosities of ∼45% and ∼36% for capillaries composed of single and mixed YSZ powders, respectively. By increasing the membrane pore size, reduced virus retention capacities in combination with increased water permeate fluxes are achieved. Capillaries made of YSZ-40 nm ensure both, log reduction values (LRV) ≥ 4 for small model bacteriophages MS2 and PhiX174 and high water permeate fluxes (∼30 L/(m2 hbar)), being suitable for sustainable virus filtration as requested by the World Health Organisation (WHO) and the United States Environmental Protection Agency (USEPA). Due to long-term virus filtration for two weeks, membrane pore plugging is successfully avoided by iterative backflushing and relatively high membrane fluxes in combination with requested LRV 4 level fulfilling the virus filter criterion are achieved.
A cavity-mediated collective quantum effect in sonoluminescing bubbles
Creators: name: Beige, Almut
name: Kim, Oleg
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This paper discusses a collective quantum effect which might play an important role in sonoluminescence experiments. We suggest that it occurs during the final stages of the collapse phase and enhances the heating of the particles inside the bubble.
description: 4 pages, 1 figure, Proceedings of the 9th International Symposium on Cavitation CAV 2015
title: The possibilities of dual-energy computed tomography (DECT) in evaluation of liver focal lesions.
Creators: name: Chaban, Artem
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Haemangioma
subject: Cysts
subject: Computer Applications-Detection, diagnosis
subject: CT
subject: Oncology
subject: Liver
subject: Abdomen
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To explore the various methods of liver focal lesion evaluation with...
The Tourism Promotion Application of 7 food menus that must be tasted in Phetchabun province with the augmented Reality Technology
Creators: name: Saranya Tritose
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2019
Subjects: subject: Tourism
subject: FOS: Economics and business
subject: Augmented Reality
subject: Food
subject: Phetchabun
subject: Thai tourists

description: Journal of Information Science and Technology, 9, 1, 9-17