cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Atomistic simulations of dynamic interaction between grain boundaries and solute clusters
Creators: name: Wicaksono, Aulia Tegar
Publisher: name: University of British Columbia
Year: 2015

description: Microstructure evolution during material processing is determined by a number of factors, such as the kinetics of grain boundary migration in the presence of impurities, which can take form of solid solution, second-phase precipitates or clusters. The dynamic interaction between grain boundaries and clusters has not been explored. In this work, a variety of simulation tools are utilized to approach this problem from an atomistic perspective. Atomistic simulations are first implemented to explore the parameter space of the solute drag problem, i.e. grain boundary migration in a binary ideal solid solution system, via a kinetic Monte Carlo framework. Depending on their diffusivity, solute atoms are capable of modifying the structure of a migrating boundary, leading to a diffusion-dependent drag pressure. A phenomenological model adapted from the Cahn model is proposed to explain the simulation results. The interaction between clusters and a migrating grain boundary is studied next using molecular dynamics simulations. The iron helium (Fe-He) system is chosen as the object of the study. A preliminary step towards such a study is to investigate the grain boundary migration in pure bcc Fe. An emphasis is placed upon demonstrating the correlation between the migration of curved and planar boundaries. Evidence that verifies such a correlation is established, based on the analyses on the shapes, the kinetics and the migration mechanism of both types of boundaries. Next, the formation of He clusters in the bulk and grain boundaries of Fe is examined. The cluster formation at the boundary occurs at a lower rate relative to that in the bulk. This is attributed to the boundary being a slow diffusion channel for interstitial He atoms. The overall effect of clusters on the boundary migration is twofold. Clusters reduce the boundary mobility via segregation; the magnitude of their effect can be rationalized using the Cahn model in the zero velocity limit. Clusters also act as pinning sources, delaying or even completely halting the boundary migration. A phenomenological model adapted from the Zener pinning model is used to discuss the role of clusters on grain boundary migration.
PORTUGALIAE Monumenta Misericordiarum. Ed. lit. do Centro de Estudos de História Religiosa da Universidade Católica Portuguesa. Coord. científica de José Pedro Paiva. Lisboa: União das Misericórdias Portuguesas, 2002
Creators: name: Marques, João Francisco
Publisher: name: Lusitania Sacra
Year: 2005

description: Lusitania Sacra, n. 17 (2005): Clérigos e Religiosos na Sociedade Medieval
Adaptive creation of orthogonal anisotropic triangular meshes using target matrices
Creators: name: Zuniga Vazquez, Jose David
Publisher: name: University of British Columbia
Year: 2015

description: We present a new procedure to adaptively produce anisotropic metric-orthogonal meshes in this thesis. The approach is based on mesh optimization techniques: point insertion designed to improve mesh alignment as well as conforming to a metric, swapping in the metric space, point movement defined by target elements from a metric, and point deletion based on quality and metric length. These techniques are intended to produce quasi-structured meshes which have the advantages of flexibility for complex geometries of unstructured meshes and the directional accuracy of structured meshes. The result is reliable alignment for anisotropic meshes reducing our previous work's reliance on smoothing for good alignment. The methodology is implemented in 2D and extended to 3D. Examples of analytical metrics and error estimation metrics on a numerical simulation of a flow are shown.
O quotidiano da Casa de D. Lourenço Rodrigues, Bispo de Lisboa (1359-1364): notas de investigação
Creators: name: Saraiva, Anísio Miguel De Sousa
Publisher: name: Lusitania Sacra
Year: 2005

description: Lusitania Sacra, n. 17 (2005): Clérigos e Religiosos na Sociedade Medieval
Star formation history of barred disc galaxies
Creators: name: Sanchez-Blazquez, Patricia
name: Ocvirk, Pierre
name: Gibson, Brad K.
name: Perez, Isabel
name: Peletier, Reynier F.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present the first results of a pilot study aimed at understanding the influence of bars on the evolution of galaxy discs through the study of their stellar content. We examine here the kinematics, star formation history, mass-weighted, luminosity-weighted, and single stellar population (SSP) equivalent ages and metallicities for four galaxies ranging from lenticulars to late-type spirals. The data employed extends to 2-3 disc scalelengths, with S/N(A)>50. Several techniques are explored to derive star formation histories and SSP-equivalent parameters, each of which are shown to be compatible. We demostrate that the age-metallicity degeneracy is highly reduced by using spectral fitting techniques --instead of indices-- to derive these parameters. We found that the majority of the stellar mass in our sample is composed of old (~10 Gyr) stars. This is true in the bulge and the disc region, even beyond two disc scalelengths. In the bulge region, we find that the young, dynamically cold, structures produced by the presence of the bar (e.g., nuclear discs or rings) are responsible for shaping the bulges' age and metallicity gradients. In the disc region, a larger fraction of young stars is present in the external parts of the disc compared with the inner disc. The disc growth is, therefore, compatible with a moderate inside-out formation scenario, where the luminosity weighted age changes from ~10 Gyrs in the centre, to ~4 Gyrs at two disc scalelengths, depending upon the galaxy. For two galaxies, we compare the metallicity and age gradients of the disc major axis with that of the bar, finding very important differences. In particular, the stellar population of the bar is more similar to the bulge than to the disc, indicating that, at least in those two galaxies, bars formed long ago and have survived to the present day. (abridged)
description: 24 pages, 23 figures, accepted for publication in MNRAS
Antibiotics for induction and maintenance of remission in ulcerative colitis: systematic review and meta-analysis
Creators: name: Mishra, Shubhra
name: Jha, Daya Krishna
name: Singh, Anupam Kumar
name: Kumar-M, Praveen
name: Patil, Amol
name: Sharma, Vishal
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Objectives: To ascertain the role of antibiotics in induction and maintenance of remission in ulcerative colitis (UC) Methods: We searched electronic databases for keywords ulcerative colitis or inflammatory bowel disease and antibiotics or antimicrobials. We performed a meta-analysis of randomized trials comparing antibiotics with control/placebo for clinical response, need for second line therapy, colectomy, and adverse effects. Subgroup analysis to clarify the mode of administration, number of antibiotics or the setting of use (acute severe UC or active non–severe UC) were also performed. Results: Thirteen trials with 785 patients were included. The pooled odds ratio of achieving clinical response with antibiotics was 1.74 (95% CI, 1.17-2.58). No differences were noted in relapse rates, need for second line therapy, colectomy or, adverse effects with the use of antibiotics. Subgroup analysis showed no differences with use of single or combination of antibiotics. Analysis of trials only in the setting of acute severe colitis did not demonstrate any benefit. Conclusion: The use of oral antibiotics in the setting of non-severe active UC could have some benefit in clinical response. The use of antibiotics is not of benefit in acute severe colitis, but oral antibiotics need to be evaluated in adult patients.
Neutral Higgs boson pair production at the LC in the Noncommutative Standard Model
Creators: name: Das, Prasanta Kumar
name: Prakash, Abhishodh
name: Mitra, Anupam
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the Higgs boson pair production through $e^+e^-$ collision in the noncommutative(NC) extension of the standard model using the Seiberg-Witten maps of this to the first order of the noncommutative parameter $Θ_{μν}$. This process is forbidden in the standard model with background space-time being commutative. We find that the cross section of the pair production of Higgs boson (of intermediate and heavy mass) at the future Linear Collider(LC) can be quite significant for the NC scale $Λ$ lying in the range $0.5 - 1.0$ TeV. Finally, using the direct experimental(LEP II, Tevatron and global electro-weak fit) bound on Higgs mass, we obtain bounds on the NC scale as 665 GeV $\le Λ\le 998$ GeV.
description: 14 pages, 8 figures
Additional file 1 of Screening programs for common maternal mental health disorders among perinatal women: report of the systematic review of evidence
Creators: name: Waqas, Ahmed
name: Koukab, Ahmreen
name: Meraj, Hafsa
name: Dua, Tarun
name: Chowdhary, Neerja
name: Fatima, Batool
name: Rahman, Atif
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary Figure 1. Effectiveness of screening programmes in perinatal depression. Supplementary Figure 2. Effectiveness of screening programmes in perinatal state anxiety. Supplementary Figure 3. Effectiveness of screening programmes in perinatal psychological quality of life. Supplementary Figure 4. Effectiveness of screening programmes in perinatal physical quality of life. Supplementary Figure 5. Effectiveness of screening programmes in improving treatment seeking behaviours. Supplementary Figure 6. Funnel plot visualizing publication bias in reporting of depression outcome. Supplementary Figure7. Summary of risk of bias across studies.
A Tale of Two Cities: An Experiment on Inequality and Preferences
Creators: name: Bigoni, Maria
name: Bortolotti, Stefania
name: Rattini, Veronica
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2019
Subjects: SECS-P/01 Economia politica

description: We study how differences in socio-economic background correlate with preferences and beliefs, in a sample of college students born in a mid-sized Italian city. Our findings indicate that participants living in an area characterized by a high socio-economic environment tend to trust more and are more inclined to reciprocate higher levels of trust, as compared to those coming from less wealthy neighborhoods. This behavioral difference is, at least in part, driven by heterogeneities in beliefs: subjects from the most affluent part of the city have more optimistic expectations on their counterpart's trustworthiness than those living in a lower socio-economic environment. By contrast, no significant differences emerge in other preferences: generosity, risk-attitudes, and time preferences. Finally, we do not find any systematic evidence of out-group discrimination based on neighborhood identity.
title: Ernst Hermann Müller-Schürch
title: 1882-1948
titleType: Subtitle
Creators: name: Jeangros, Erwin
Publisher: name: Zentralbibliothek Zürich
Year: 1948
Subjects: subject: 610 Medizin und Gesundheit
subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Zürich
subject: Oetwil am See

description: Abdruck aus: Verhandlungen der Schweizerischen Naturforschenden Gesellschaft, 1948, Seiten 352-354
Contrapunteo entre los discursos sobre violencia en El Tiempo, crónicas independientes, y el hip hop de la comuna 13 de Medellín, 2002-2012
Creators: name: Alvarez Jaimes, Javier
Publisher: name: University of British Columbia
Year: 2015

description: Since 2002, the San Javier district known as Comuna 13 in Medellín, Colombia, has occupied a space in the imagination of Colombians as a violent and dangerous area. Comuna 13, a marginalized neighborhood in the city’s urban sprawl, had been receiving for decades the displaced victims of the violence of the armed conflict in the countryside as well as people from other towns and rural areas attracted by Medellín’s reputation as a progressive and developed city. This thesis analyzes the news articles referring to Comuna 13 in El Tiempo, a widely circulated newspaper in Colombia and a powerful tool of manufacturing public consent, articles which persistently associate the area with violence in the public perception as a result of military operations Mariscal and Orión, launched by the government to disband groups of urban guerrillas that had taken hold in this segregated area of Medellín. Key discussions of the place, including Comuna 13: Crónica de una guerra urbana (2007) by Ricardo Aricapa and Crónicas en el barrio El Salado by Albeiro Ospina dialogue with the discourse of the press, while giving voice to the residents who account for their own versions of violence. These narratives are contrasted with the political actions of youth movements through hip hop which empowers them to create their own poetics of space. The four elements of hip hop (rap, graffiti, breakdance and DJing), practiced by young residents, who have taken to the streets occupying them with sounds, movements and images, become tools in the production of space, reconfiguring in epic dimensions their own perception of Comuna 13.
Evidence of a distinct stellar population in the counter-rotating core of NGC 1700
Creators: name: Kleineberg, K.
name: Sanchez-Blazquez, P.
name: Vazdekis, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We find a distinct stellar population in the counter-rotating and kinematically decoupled core of the isolated massive elliptical galaxy NGC 1700. Coinciding with the edge of this core we find a significant change in the slope of the gradient of various representative absorption line indices. Our age estimate for this core is markedly younger than the main body of the galaxy. We find lower values for the age, metallicity and Mg/Fe abundance ratio in the center of this galaxy when we compare them with other isolated elliptical galaxies with similar velocity dispersion. We discuss the different possible scenarios that might have lead to the formation of this younger kinematically decoupled structure and conclude that, in light of our findings, the ingestion of a small stellar companion on a retrograde orbit is the most favoured.
description: 13 pages, 5 figures, accepted for publication in ApJL
Creation and characterization of BAC-transgenic mice with physiological over-expression of epitope-tagged RCAN1 (DSCR1)
Creators: name: Xing, Luzhou
name: Salas, Martha
name: Zhang, Hong
name: Gittler, Julia
name: Ludwig, Thomas
name: Lin, Chyuan-Sheng
name: Vundavalli, Murty V.
name: Silverman, Wayne
name: Arancio, Ottavio
name: Tycko, Benjamin
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Genomics
subject: Genetics
subject: FOS: Biological sciences
subject: Human chromosome 21
subject: Down syndrome--Genetic aspects
subject: Transgenic mice

description: The chromosome 21 gene RCAN1, encoding a modulator of the calcineurin (CaN) phosphatase, is a candidate gene for contributing to cognitive disability in people with Down syndrome (DS; trisomy 21). To develop a physiologically relevant model for studying the biochemistry of RCAN1 and its contribution to DS, we generated bacterial artificial chromosome-transgenic (BAC-Tg) mouse lines containing the human RCAN1 gene with a C-terminal HA-FLAG epitope tag incorporated by recombineering. The BAC-Tg was expressed at levels only moderately higher than the native Rcan1 gene; approximately 1.5-fold in RCAN1BAC-Tg1 and 2-fold in RCAN1BAC-Tg2. Affinity purification of the RCAN1 protein complex from brains of these mice revealed a core complex of RCAN1 with calcineurin (CaN), glycogen synthase kinase 3-beta (Gsk3b), and calmodulin, with sub-stoichiometric components including LOC73419. The BAC- Tg mice are fully viable, but long-term synaptic potentiation (LTP) is impaired in proportion to BAC-Tg dosage in hippocampal brain slices from these mice. RCAN1 can act as a tumor suppressor in some systems, but we found that the RCAN1 BAC-Tg did not reduce mammary cancer growth when present at a low copy number in Tp53;WAP-Cre mice. This work establishes a useful mouse model for investigating the biochemistry and dose-dependent functions of the RCAN1 protein in vivo.
On string integrability. A journey through the two-dimensional hidden symmetries in the AdS/CFT dualities
Creators: name: Puletti, Valentina Giangreco M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: One of the main topics in the modern String Theory are the AdS/CFT dualities. Proving such conjectures is extremely difficult since the gauge and string theory perturbative regimes do not overlap. In this perspective, the discovery of infinitely many conserved charges, i.e. the integrability, in the planar AdS/CFT has allowed us to reach immense progresses in understanding and confirming the duality. We review the fundamental concepts and properties of integrability in two-dimensional sigma-models and in the AdS/CFT context. The first part is focused on the AdS_5/CFT_4 duality, especially the classical and quantum integrability of the type IIB superstring on AdS_5 x S^5 are discussed in both pure spinor and Green-Schwarz formulations. The second part is dedicated to the AdS_4/CFT_3 duality with particular attention to the type IIA superstring on AdS_4 x CP^3 and its integrability. This review is based on a shortened and revised version of the author's PhD thesis, discussed at Uppsala University in September 2009.
description: 116 pages, 11 figures, to be published in Advances in High Energy Physics, Special Issue on ''Gauge/String Duality''
Cluster counting in drift chambers for particle identification and tracking
Creators: name: Caron, Jean-François
Publisher: name: University of British Columbia
Year: 2015

description: Drift chambers are a type of gaseous ionization detector used in high-energy physics experiments. They can identify charged particles and measure their momentum. When a high-energy charged particle crosses the drift chamber, it ionizes the gas. The liberated electrons drift towards positive-high-voltage wires where an ionization avalanche amplifies the signal. Traditional drift chambers use only the arrival time of the cluster of charge from the closest ionization for tracking, and use only the integral of the whole signal for particle identification. We constructed prototype drift chambers with the ability to resolve the charge cluster signals from individual ionization events. Different algorithms were studied and optimized to best detect the clusters. The improvements to particle identification were studied using a single-cell prototype detector, while the improvements to particle tracking were studied using a multiple-layer prototype. The prototypes were built in the context of initial work for the now-cancelled SuperB project, but the results apply to any drift chambers used in flavour-factory experiments. The results show that the choice of algorithm is not as critical as properly optimizing the algorithm parameters for the dataset. We find that a smoothing time of a few nanoseconds is optimal. This corresponds to bandwidth of a few hundred megahertz, indicating that gigahertz-bandwidth electronics are not required to make use of this technique. Particle identification performance is quantified by the fraction of real pions correctly identified as pions with at most 10% of real pions mis-identified as muons. In our single-cell prototype, the performance increases from 50% to 60% of pions correctly identified when cluster counting is combined with a traditional truncated-mean charge measurement, compared to the charge measurement alone. Tracking performance is quantified by the single-cell resolution: the uncertainty in measuring the distance of charged particle tracks from a given sense wire. In our multiple-layer prototype, the single-cell tracking resolution using traditional methods is measured to be ~150μm. With cluster counting implemented, the resolution is unchanged, indicating that the additional cluster information is not useful.
An Exploration of Symmetries in the Friedmann Equation
Creators: name: Ibison, M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences
subject: 83F05, 83C75, 81T20

description: The Friedmann Equation for a conformal scale factor a(t) is observed to be invariant under a Mobius transformation. Using that freedom, a synthetic scale factor z(t) is defined that obeys a modified Friedman equation invariant under the replacement z(t) {\rightarrow} {\pm}1/ z(t). If this is taken this to be the more fundamental form then the traditional Friedmann equation can be shown to be missing a term due to a species with equation of state w = -2/3. We investigate in detail one particular cosmology in which it is possible to specify the contribution from this new species. We suggest a means of avoiding a potentially redundant copy of the development of the universe the above implies through a cosmological spacetime manifold that is a Mobius band closed in time and non-orientable in space. Though it is closed, a Dirac field in such a spacetime may still possess a global arrow of time by virtue of the twist of the Mobius band.
description: To appear in Proceedings of "Quantum Retrocausation: Theory and Experiment
Em torno da historiografia das Ordens Militares Hispânicas: uma leitura da obra Las órdenes militares hispánicas en la edad media (siglos XII-XV) de Carlos de Ayala Martínez
Creators: name: Marques, André Evangelista
Publisher: name: Lusitania Sacra
Year: 2005

description: Lusitania Sacra, n. 17 (2005): Clérigos e Religiosos na Sociedade Medieval
Additional file 1 of Molecular features of glioblastomas in long-term survivors compared to short-term survivors—a matched-pair analysis
Creators: name: Sommerlath, Vivien N.
name: Buergy, Daniel
name: Etminan, Nima
name: Brehmer, Stefanie
name: Reuss, David
name: Sarria, Gustavo R.
name: Guiot, Marie-Christin
name: Hänggi, Daniel
name: Wenz, Frederik
name: Petrecca, Kevin
name: Giordano, Frank A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology

description: Additional file 1: figure S1. a) Overall survival in long-term survivors compared to short-term survivors-1. b) Overall survival in long-term survivors compared to short-term survivors-2.
Coronal fuzziness modelled with pulse-heated multistranded loop systems
Creators: name: Guarrasi, Massimiliano
name: Reale, Fabio
name: Peres, Giovanni
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Coronal active regions are observed to get fuzzier and fuzzier (i.e. more and more confused and uniform) in harder and harder energy bands or lines. We explain this evidence as due to the fine multi-temperature structure of coronal loops. To this end, we model bundles of loops made of thin strands, each heated by short and intense heat pulses. For simplicity, we assume that the heat pulses are all equal and triggered only once in each strand at a random time. The pulse intensity and cadence are selected so as to have steady active region loops ($\sim 3$ MK), on the average. We compute the evolution of the confined heated plasma with a hydrodynamic loop model. We then compute the emission along each strand in several spectral lines, from cool ($\leq 1$ MK), to warm ($2-3$ MK) lines, detectable with Hinode/EIS, to hot X-ray lines. The strands are then put side-by-side to construct an active region loop bundle. We find that in the warm lines ($2-3$ MK) the loop emission fills all the available image surface. Therefore the emission appears quite uniform and it is difficult to resolve the single loops, while in the cool lines the loops are considerably more contrasted and the region is less fuzzy. The main reasons for this effect are that, during their evolution, i.e. pulse heating and slow cooling, each strand spends a relatively long time at temperatures around $2-3$ MK, and that it has a high emission measure during that phase, so the whole region appears more uniform or smudged. We make the prediction that the fuzziness should be reduced in the hot UV and X-ray lines.
description: 27 pages, 14 figures
Evaluation of the role of ANGPTL4 in tendon vascularization
Creators: name: Mousavizadeh Ahmadabadi, Seyed Rouhollah
Publisher: name: University of British Columbia
Year: 2015

description: The mechanisms that regulate angiogenic activity in injured or mechanically loaded tendons are poorly understood. In this study we hypothesised that repetitive stretching of tendon cells alters the expression and release of angiogenic factors which may promote tendon vascularization. In order to examine the effects of repetitive stretching on the expression of angiogenic genes, primary human tendon cells were subjected to cyclic stretching. Cyclic stretching of two-dimensional primary tenocyte cell cultures increased the expression of VEGF, bFGF and Cox-2. But, by extending the time course, VEGF, bFGF and Cox-2 were progressively downregulated. Angiogenic profiling of tendon cells by qPCR array identified a number of other genes (ANGPTL4, FGF-1, TGFα, VEGF-C and SPHK1) that responded to tensile loading in a similar pattern. Further experiments revealed that cyclic stretching of human tendon fibroblasts stimulated the expression and release of ANGPTL4 protein via TGF-β and HIF-1α signalling. ANGPTL4 promoted the angiogenic activity of endothelial cells. Angiogenic activity was also increased following injury and following ANGPTL4 injection into mouse patellar tendons, whereas the patellar tendons of ANGPTL4 knock out mice displayed reduced angiogenesis following injury. In human rotator cuff tendons, there were both spatial and quantitative associations of ANGPTL4 with tendon endothelial cells. The experiments described in this thesis have shown that ANGPTL4 may assist in the regulation of vascularity in injured or mechanically loaded tendon. TGF-β and HIF-1α are two signalling pathways that modulate the expression of ANGPTL4 by tendon fibroblasts and which could, in future, be manipulated to influence tendon healing or adaptation.
One in Four Individuals of African-American Ancestry Harbors a 5.5kb Deletion at chromosome 11q13.1
Creators: name: Zainabadi, Kayvan
name: Jain, Anuja V.
name: Donovan, Frank X.
name: Elashoff, David
name: Rao, Nagesh P.
name: Vundavalli, Murty V.
name: Chandrasekharappa, Settara C.
name: Srivatsan, Eri S.
Publisher: name: Columbia University
Year: 2014
Subjects: Genomics
Chromosomes
Single nucleotide polymorphisms
Linkage (Genetics)
African Americans
Cervix uteri--Cancer

description: Cloning and sequencing of 5.5kb deletion at chromosome 11q13.1 from the HeLa cells, tumorigenic hybrids and two fibroblast cell lines has revealed homologous recombination between AluSx and AluY resulting in the deletion of intervening sequences. Long-range PCR of the 5.5kb sequence in 494 normal lymphocyte samples showed heterozygous deletion in 28.3% of African- American ancestry samples but only in 4.8% of Caucasian samples (p<0.0001). This observation is strengthened by the copy number variation (CNV) data of the HapMap samples which showed that this deletion occurs in 27% of YRI (Yoruba – West African) population but none in non- African populations. The HapMap analysis further identified strong linkage disequilibrium between 5 single nucleotide polymorphisms and the 5.5kb deletion in the people of African ancestry. Computational analysis of 175kb sequence surrounding the deletion site revealed enhanced flexibility, low thermodynamic stability, high repetitiveness, and stable stem-loop/ hairpin secondary structures that are hallmarks of common fragile sites.
Two methods for solving optimization problems arising in electronic measurements and electrical engineering
Creators: name: Sergeyev, Yaroslav D.
name: Daponte, Pasquale
name: Grimaldi, Domenico
name: Molinaro, Anna
Publisher: name: arXiv
Year: 2011
Subjects: subject: Numerical Analysis (math.NA)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Optimization and Control (math.OC)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences
subject: 90C30, 94A12, 65Z05

description: In this paper we introduce a common problem in electronic measurements and electrical engineering: finding the first root from the left of an equation in the presence of some initial conditions. We present examples of electrotechnical devices (analog signal filtering), where it is necessary to solve it. Two new methods for solving this problem, based on global optimization ideas, are introduced. The first uses the exact a priori given global Lipschitz constant for the first derivative. The second method adaptively estimates local Lipschitz constants during the search. Both algorithms either find the first root from the left or determine the global minimizers (in the case when the objective function has no roots). Sufficient conditions for convergence of the new methods to the desired solution are established in both cases. The results of numerical experiments for real problems and a set of test functions are also presented.
A spoonful of silly : examining the relationship between children's nonsense verse and critical literacy
Creators: name: Tulloch, Bonnie
Publisher: name: University of British Columbia
Year: 2015

description: This thesis interrogates the common assumption that nonsense literature makes “no sense.” Building off research in the fields of English and Education that suggests the intellectual value of literary nonsense, this study explores the nonsense verse of several North American children’s poets to determine if and how their play with language disrupts the colonizing agenda of children’s literature. Adopting the critical lenses of Translation Theory and Postcolonial Theory in its discussion of Dr. Seuss’s On Beyond Zebra! (1955) and I Can Read with My Eyes Shut! (1978), along with selected poems from Shel Silverstein’s Where the Sidewalk Ends (1974), A Light in the Attic (1981), Runny Babbit (2005), Dennis Lee’s Alligator Pie (1974), Nicholas Knock and Other People (1974), and JonArno Lawson’s Black Stars in a White Night Sky (2006) and Down in the Bottom of the Bottom of the Box (2012), this thesis examines how the foreignizing effect of nonsense verse exposes the hidden adult presence within children’s literature, reminding children that childhood is essentially an adult concept—a subjective interpretation (i.e., translation) of their lived experiences. Analyzing the way these poets’ nonsense verse deviates from cultural norms and exposes the hidden adult presence within children’s literature, this research considers the way their poetry assumes a knowledgeable implied reader, one who is capable of critically engaging with the text. Discussing the implications of this reader position, this study ends by reflecting on the potential relationship between nonsense verse and critical literacy.
CESSDA's Software Maturity Model
Creators: name: Shepherdson, John
Publisher: name: Zenodo
Year: 2019
Subjects: Software
Quality

description: Over the last couple of years, CESSDA has built-up and improved a comprehensive infrastructure that provides a development and test environment available to all CESSDA Service Providers – at least those who develop software for CESSDA. This environment makes use of modern technologies such as Bitbucket, Jenkins, Selenium, and SonarQube. To enhance the reproducibility, reliability, and scalability of the components that form part of the CESSDA tools and services portfolio, it also uses containerisation (Docker) and clustering (Kubernetes).

However, having a powerful development and deployment infrastructure for the CESSDA Service Provider community is not enough. It is also important to ensure that all developers that contribute software are developing it in a consistent and reusable way and are aware of what is expected of them. The latest version of the CESSDA Software Maturity Levels document sets quality standards across twelve criteria and is used to determine whether or not contributed software is of a standard to be accepted and deployed.
Ordres religieux et histoire culturelle dans l’occident médiéval
Creators: name: Rucquoi, Adeline
Publisher: name: Lusitania Sacra
Year: 2005

description: Com muito poucas excepções, as regras monásticas elaboradas desde o século IV não promovem o saber nem a curiosidade intelectual; embora tenha que ler e meditar, o monge procura afastar-se do mundo e das suas tentações. Somente a partir do século XII algumas ordens contemplaram o ensino e a pregação entre os seus objectivos, embora desde a alta idade média alguns mosteiros se tivessem tornado famosos pela escola que criaram, pela sua biblioteca e pelo seu scriptorium, tendo assim contribuído para a preservação da cultura clássica e patrística. Pondo de parte as grandes figuras que, por serem indivíduos excepcionais, não representam o conjunto da ordem a que pertencem, este artigo procura sublinhar o contributo das ordens religiosas para uma série de campos específicos da cultura medieval: hagiografia, historiografia, literatura escatológica, teologia, retórica e espiritualidade.
description: Lusitania Sacra, n. 17 (2005): Clérigos e Religiosos na Sociedade Medieval
Additional file 1 of Lessons to be learned: identifying high-risk medication and circumstances in patients at risk for suicidal self-poisoning
Creators: name: Geith, Stefanie
name: Didden, Christiane
name: Rabe, Christian
name: Zellner, Tobias
name: Ott, Armin
name: Eyer, Florian
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Geith et al. 2021_Supplement 1. Lessons to be learned: Identifying high-risk medication and circumstances in patients at risk for suicidal self-poisoning—Modified poison emergency call record.
A survey of underwater wireless optical communication
Creators: name: Zeng, Zhaoquan
Publisher: name: University of British Columbia
Year: 2015

description: Underwater wireless communication refers to transmitting data in unguided water environment through the use of wireless carriers, i.e., radio-frequency wave, acoustic wave, and optical wave. We focus, in this thesis, on the underwater wireless optical communication (UWOC) that employs optical wave as the transmission carriers. In comparison to RF and acoustic counterparts, UWOC has a much higher transmission bandwidth, thus providing much higher data rate. Due to this high-speed transmission advantage, UWOC has attracted considerable attention in recent years. Many potential applications of UWOC systems have been proposed for environmental monitoring, offshore exploration, disaster precaution, and military operations. However, UWOC systems also suffer from severe absorption and scattering introduced by underwater channel. In order to overcome these technical challenges, several new system design approaches, which are different from the conventional terrestrial free-space optical communication, have been explored in recent years. In this thesis, we provide a comprehensive survey of the state-of-the-art of UWOC research in three aspects: channel characterization, channel modulation and coding techniques, and practical implementations of UWOC. Based on the comprehensive understanding of UWOC, we also investigate the outage performance for vertical buoy-based UWOC with pointing errors. Closed-form outage probability with zero boresight pointing errors and outage probability bounds with nonzero boresight pointing errors have been derived.
Metric radio bursts and fine structures observed on 17 January, 2005
Creators: name: Bouratzis, C.
name: Preka-Papadema, P.
name: Moussas, X.
name: Alissandrakis, C.
name: Hillaris, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: A complex radio event was observed on January 17, 2005 with the radio-spectrograph ARTEMIS-IV, operating at Thermopylae, Greece; it was associated with an X3.8 SXR flare and two fast Halo CMEs in close succession. We present dynamic spectra of this event; the high time resolution (1/100 s) of the data in the 450-270 MHz range, makes possible the detection and analysis of the fine structure which this major radio event exhibits. The fine structure was found to match, almost, the comprehensive Ondrejov Catalogue which it refers to the spectral range 0.8-2 GHz, yet seems to produce similar fine structure with the metric range.
description: Advances in Space Research, Volume 43, Issue 4, p. 605-611
Organisation sociale et altérité culturelle dans l’hagionymie médiévale du Midi portugais
Creators: name: Boissellier, Stéphane
Publisher: name: Lusitania Sacra
Year: 2005

description: O rol da décima das igrejas paroquiais portuguesas de 1320 fornece um panorama das devoções mais institucionais na região a sul do Tejo, nos finais da fase colonial da sua organização. A estrutura do documento constrange-nos a interpretar social e institucionalmente as devoções e encarar a religiosidade enquanto elemento das identidades locais e sociais. Com base na análise estatística dos 200 padroados celestes identificados (estreiteza do leque hagionímico, monopólio da espiritualidade marial, importância das referências evangélicas, universalidade dos patronos até raros na região), mormente na sua repartição geográfica, tenta-se a identificação dos mecanismos sócio-culturais; dentro dos quais, parecem-me fulcrais o conformismo espiritual e o desejo de coesão cívica. As tendências particularizantes e comunitarizantes, devidas à diversidade cultural e sócio-espacial das populações (indígenas muçulmanos, moçárabes neo-cristãos, colonos portugueses e estrangeiros // elites de milites das sedes dos concelhos mais antigos, residentes nas «aldeias») e às estratégias devocionais individuais das camas senhoriais e eclesiásticas, estão para buscar nos títulos dos templos menores, que precisamente faltam no documento.
description: Lusitania Sacra, n. 17 (2005): Clérigos e Religiosos na Sociedade Medieval
Additional file 2 of Lessons to be learned: identifying high-risk medication and circumstances in patients at risk for suicidal self-poisoning
Creators: name: Geith, Stefanie
name: Didden, Christiane
name: Rabe, Christian
name: Zellner, Tobias
name: Ott, Armin
name: Eyer, Florian
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2: Geith et al. 2021_Supplement 2. Lessons to be learned: Identifying high-risk medication and circumstances in patients at risk for suicidal self-poisoning—Pairwise comparison of reasons for SRB in different age groups.
Commutability of reference materials for alkaline phosphatase measurements
Creators: name: Guo, Qi
name: Wang, Jing
name: Yi, Xilian
name: Zeng, Jie
name: Zhou, Weiyan
name: Zhao, Haijian
name: Zhang, Tianjiao
name: Zhang, Chuanbao
Publisher: name: Taylor & Francis
Year: 2020
Subjects: Biochemistry
Medicine
Cell Biology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Commutability is a prerequisite when using a candidate reference materials (CanRMs) for calibration and trueness control of routine methods or for value transfer from the reference method to end-user calibrators of routine methods through a calibration hierarchy. The CanRMs include commercial general chemistry materials (GCs), enzyme trueness verification materials (ETVs), and secondary reference materials (SRMs). The commutability of CanRMs was evaluated based on the difference in bias and EP14-A3 to investigate their suitability for ALP measurement. A total of 44 fresh individual clinical samples (CSs) and the CanRMs were analyzed by six routine methods (validated methods) and by IFCC primary reference method (comparative method) for the determination of Alkaline Phosphatase (ALP). The commutability was performed based on IFCC working group recommendations for assessing commutability and analyzed according to EP14-A3 guide and difference in bias approach, respectively. The bias of the routine methods was assessed according to CLSI guidelines. The result of commutable materials obtained from the two evaluation approaches are not significantly different. It was observed that the routine methods with lower bias were associated with more commutable CanRMs. None of the CanRMs were suitable for use as commutable RMs. The findings of this study have a number of important implications for future practice.
Additional file 3 of Lessons to be learned: identifying high-risk medication and circumstances in patients at risk for suicidal self-poisoning
Creators: name: Geith, Stefanie
name: Didden, Christiane
name: Rabe, Christian
name: Zellner, Tobias
name: Ott, Armin
name: Eyer, Florian
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3: Geith et al. 2021_Supplement 3. Lessons to be learned: Identifying high-risk medication and circumstances in patients at risk for suicidal self-poisoning—Overview about literature research with respect to self-intoxication in correlation to age, gender, and substances used.
Fr. João da Póvoa e o movimento da Observância Franciscana Portuguesa entre 1447 e 1517
Creators: name: Teixeira, Vítor Gomes
Publisher: name: Lusitania Sacra
Year: 2005

description: Fr. João da Póvoa foi a maior figura do processo de estruturação e definição territorial e espiritual da Observância franciscana em Portugal, crucial e incontornável no processo de implantação e consolidação daquele movimento reformador menorita em Portugal até à sua morte, em 1506. Foi confessor de D. João II, colaborador de D. Leonor e de D. Manuel. Produto do incremento dos estudos na Observância, foi também um dos maiores impulsionadores da cultura entre os seus confrades e fautor do enriquecimento das bibliotecas e scriptoria dos cenóbios franciscanos coevos. Fr. João da Póvoa é talvez a maior figura da nova espiritualidade de finais de Quatrocentos, o religioso mais importante da sua Ordem, o mais ilustre da Observância e o clérigo que manteve mais fortes e praticantes os preceitos apostólicos da vida eclesial do seu tempo.
description: Lusitania Sacra, n. 17 (2005): Clérigos e Religiosos na Sociedade Medieval
Reclaiming Kwak'wala through co-constructing G̲wa̲nti'lakw's vision
Creators: name: Cranmer, Laura
Publisher: name: University of British Columbia
Year: 2015

description: This dissertation is a self-study about my attempt to re-claim my heritage language of Kwak’wala. As a critically endangered language, the First Peoples’ Cultural Council Report on the Status of BC First Nations Languages 2014 found that of a population of 7,309 Kwakwa̲ka̲’wakw reporting to the council about numbers of fluent and semi-fluent Kwak’wala speakers, there are only 160 fluent speakers with approximately 497 identified semi-speakers. I have written from a critical Indigenous Studies stance, drawing from compatible fields such as narrative inquiry and auto-ethnography, and second language acquisition (SLA) theories as well as the growing field of identity theory and heritage language learning within SLA. Further, I asked for and received permission from three Kwakwa̲ka̲’wakw First Nations to interview fluent Kwak’wala speakers in response to a sampling of photographs from my paternal grandmother G̲wa̲nti’lakw’s archive. As a teenager and young mother, she took many photos of our relatives who originated from our large clan with connections to far flung villages within the territory. G̲wa̲nti’lakw was responsible for my care as an infant, and during my formative years, and for a while I knew her as Mom until I grew older and could understand my true beginnings and place in our family. Through an autoethnographic narrative and analysis, I provide a reflection on my engagement with Kwak’wala and its speakers and my own identity as a language learner attempting to reclaim Kwak’wala. As an adult learner, I apply my print literacy skills to phonological memories from my childhood in order to deepen my understanding of the how Kwak’wala works grammatically, lexically and syntactically.
An Infinite-Dimensional Family of Black-Hole Microstate Geometries
Creators: name: Bena, Iosif
name: Bobev, Nikolay
name: Giusto, Stefano
name: Ruef, Clement
name: Warner, Nicholas P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct the first explicit, smooth, horizonless black-hole microstate geometry whose moduli space is described by an arbitrary function of one variable and is thus infinite-dimensional. This is achieved by constructing the scalar Green function on a simple D6 anti-D6 background, and using this Green function to obtain the fully back-reacted solution for a supertube with varying charge density in this background. We show that this supertube can store parametrically more entropy than in flat space, confirming the entropy enhancement mechanism that was predicted using brane probes. We also show that all the local properties of the fully back-reacted solution can, in fact, be obtained using the DBI action of an appropriate brane probe. In particular, the supergravity and the DBI analysis yield identical functional bubble equations that govern the relative locations of the centers. This indicates that there is a non-renormalization theorem that protects these functional equations as one moves in moduli space. Our construction creates configurations that are beyond the scope of recent arguments that appear to put strong limits on the entropy that can be found in smooth supergravity solutions.
description: 46 pages, 1 figure, LaTeX