cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Biodegradable scaffolds
Creators: name: Buchanan, Rachel
name: Smid, Christine
name: Ferrari, Mauro
name: Tasciotti, Ennio
Publisher: name: United States Patent and Trademark Office
Year: 2018
Subjects: subject: A61L27/56
subject: A61L27/16
subject: A61L27/18
subject: A61L27/20
subject: A61L27/3834
subject: A61L27/3847
subject: A61L27/446
subject: A61L27/54
subject: A61L27/58
subject: A61L2300/252
subject: A61L2300/406
subject: A61L2300/41
subject: A61L2300/44
subject: A61L2300/64
subject: A61L2430/02

description: In some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable reinforcing particle that is dispersed in the matrix. In some embodiments, the biodegradable reinforcing particle is selected from the group consisting of porous oxide particles and porous semiconductor particles. In additional embodiments, the compositions of the present invention further comprise a (3) porogen particle that is also dispersed in the matrix. In further embodiments, the compositions of the present invention are also associated with one or more active agents. In various embodiments, the active agents are associated with the biodegradable polymer matrix, the biodegradable reinforcing particle, and/or the porogen particle. In various embodiments, the compositions of the present invention may be utilized as scaffolds, such as scaffolds for treating bone defects. Further embodiments of the present invention pertain to methods of making the compositions of the present invention.
Dicordylus vanini Mermudes, 2006, sp. nov.
Creators: name: Mermudes, Record Of Serranus Anin For Razil José Ricardo M.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Belidae
Dicordylus
Dicordylus vanini

description: Dicordylus vanini sp. nov.
(Fig. 1)
Diagnosis: Dicordylus vanini sp. nov. is distinguished from the other species of the genus by: 1) dorsal vestiture with dense, decumbent, shining, reddish-orange pubescence; 2) elytra, near suture of basal 1/4 with long, decumbent, ferruginous setae, conspicuously denser at the middle of disk; 3) lacking rounded spot on elytra.
Description: Female (10.5 mm). Integument reddish-brown, darker in three last antennal segments. Dorsal vestiture with dense, decumbent, shining, reddish-orange pubescence. Elytra, near suture of basal 1/4 with long, decumbent, ferruginous setae, conspicuously denser at the middle of disk; setae inclined 45° in relation to longitudinal axis of body. Ventral surface of body and legs with sparse, yellowish-white pubescence, denser at sides of the body.
Basal half of rostrum weakly punctuate-corrugate. Front slight convex. Pronotum without longitudinal depression; near the base, slightly impressed at sides of disk. Antennae exceeding the posterior margin of prothorax by apical half of segment IX; scape twice as long as segment II; III and IV subequals in length, three times as long as II; V at least 1/3 shorter than IV; VI-IX subequals, weakly shorter than V; X slightly shorter than XI.
Elytra narrow, about 2.5x as long as wide; flattened in the middle of the disk; basal gibbosities weakly prominent. Dorsum with tufts of black, erect setae: one tuft antemedian; two before apical fourth, one outer with discrete setae; and apical declivity with two discrete tufts. Elytral apex feebly oblique, lacking abrupt declivity.
Holotype: a female from Brazil, without any additional information, collected by A.M. Parko, and deposited in the Museu Nacional, Universidade Federal do Rio de Janeiro (MNRJ).
Measurements of the holotype: total length, 10.5 mm (from vertex to elytral apex); rostrum length, 2.5 mm; prothorax length, 2.5 mm; prothorax width, 2.0 mm; elytral length, 7.0 mm; humeral width, 3.0 mm.
Etymology: This species is named for Dr. Sergio Antonio Vanin (Museu de Zoologia, Universidade de São Paulo), in recognition of his many contributions to weevils taxonomy and for his enthusiastic encouragement of others to contribute to the study of Coleoptera.
description: Published as part of Mermudes, Record Of Serranus Anin For Razil José Ricardo M., 2006, A New Species Of Dicordylus Lacordaire, 1863 From Brazil (Coleoptera, Belidae, Pachyurinae, Agnesiotidini), With A New Record Of D. Serranus Vanin 1976 For Brazil J R M. M Abstract, pp. 73-75 in Papéis Avulsos de Zoologia (São Paulo) (São Paulo) 46 (8) on pages 74-75, DOI: 10.1590/S0031-10492006000800001, http://zenodo.org/record/12640626
Synthesis of ionic boron amphiphilic diblock copolymers and pyridylborate ligands for transition metal complexes
Creators: name: Cui, Chengzhong
Publisher: name: No Publisher Supplied
Year: 2010

description: Atom transfer radical polymerization (ATRP) has been successfully used to prepare well-defined poly(trimethylsilyl)styrenes and the diblock copolymers, poly(trimethylsilyl)styrene-b-polystyrene, with controlled molecular weight and low polydispersity. Quantitative replacement of trimethylsilyl groups with boron tribromide in dichloromethane provided an important highly Lewis acidic intermediate that have allowed for the preparation of novel boron containing borate and boronium types of homopolymers and amphiphilic diblock copolymers with different post-polymerization modification processes. Characterizations including NMR spectroscopy, gel permeation chromatography (GPC) and the representative elemental analysis have been applied to confirm the quantitative transformations from the silylated polymers to the boron containing ionic polymers. The self-assembly properties in block selective solvents of the amphiphilic block copolymers were extensively studied. Most importantly, through an electro-static interaction, the weakly coordinating pentafluorophenyl borate block copolymers were successfully used to attach an organo-rhodium catalyst and then underwent self-assembly in selective solvent to give rise to transition metal containing micelles with well-defined nanostructures. In the last chapter, synthesis and characterizations of a variety of novel multidentate pyridylborate ligands are described. An appropriate procedure for synthesis of 2-pyridyl magnesium chloride in a usual dimeric structure was developed. The 2-pyridyl magnesium chloride was then used to react with different arylbromoboranes in dichloromethane or toluene affording different multidentate ligands. The tris(2-pyridyl)borate ligands were the first pyridine based tripod ligands with a boron atom as the bridging head and their complexation with Fe(II) was studied by cyclic voltammetry (CV) and UV-vis spectroscopy. All the structures of the ligands and metal complexes were determined by single crystal X-ray spectroscopy. The styryltris(2-pyridyl)borate monomer was successfully polymerized in a free radical polymerization to give a polymer with good yield and high molecular weight. NMR analysis was used to confirm the formation of this novel polydentate polymer.
title: Preparation and uses of multi-phase microspheres
Creators: name: McGinity, James W.
name: Iwata, Motokazu
Publisher: name: United States Patent and Trademark Office
Year: 1994
Subjects: subject: A61K9/1694
subject: A61K9/1647
subject: A61K9/5031
subject: A61K9/5089
subject: Y10T428/2984
subject: Y10T428/2985
subject: Y10T428/2987
subject: 424/484
subject: 424/488
subject: 424/489
subject: 424/490
subject: 424/491
subject: 428/402.2
subject: 428/402.21
subject: 428/402.22

description: Multi-phase polymeric microspheres containing a molecular compound dispersed in a polymeric matrix are described. Methods for preparing the multi-phase microspheres are also described, which includes a multiple emulsion solvent evaporation technique. Drug loading efficiencies between 80 to 100% were achieved using the described methods. Particular ratios of the W/O emulsion to polymer, and concentration of surfactant and dispersion media (mineral oil) provide highly efficient multi-phase microspheres. In particular embodiments, the multi-phase microspheres feature a high loading efficiency of water-soluble drugs, and also eliminates partitioning of the water soluble agent into the polymer acetonitrile (solvent) phase, thus preventing low encapsulation efficiency. The described multi-phase microspheres possess efficient drug loading, release properties, and drug stability, and also provide a vehicle for long term therapeutic release of a biologically active molecule for therapeutically effective periods of time. Molecular compounds which may be incorporated within the multi-phase microspheres include both water-soluble and water-insoluble drugs, proteins (e.g. TNF), peptides, and chemicals. The molecular compound is protected within an oily droplet, and contact with polymer, surfactant, organic solvents, and other potentially denaturing agents is prevented.
Episcepsis melanoneura Zerny 1931
Creators: name: Pinheiro, L. R.
name: Gaal-Haszler, S.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Arctiidae
Episcepsis
Episcepsis melanoneura

description: melanoneura Zerny, 1931
(Fig. 17)
Episcepsis melanoneura Zerny, 1931b: 17 (Taf. 1, fig. 19 and 20). Lectotype hereby designated, male: [BRAZIL], Jaraguá, Santa Catarina (Fr. Hoffmann), with three labels: printed label “Sta. Catharina, Jaraguá, Fr. Hoffmann ” with handwritten date on the underside “ 23.x. ’29” and handwritten label “ Episcepsis melanoneura Zerny male type ”. Six paralectotypes, two males and four females. Two males also from Jaraguá, but from a different date: 28.viii. [19]29. Four females from Jaraguá, with the same labels, except for the dates, which are as follows: “ 12.vi. ’28”; “ 27.v. ’29”; “ 24.viii. ’29” and “ 2.x. ’29”. Fifth female with four labels: three printed labels “27.2”, “Bahia”, and “Bras. Exped. Penther ’03”; and handwritten label “ Episcepsis melanoneura Zerny ♀ type ”.
Current combination. Episcepsis melanoneura Zerny, 1931.
Condition of the types. Lectotype. Forewings somewhat rubbed. Paralectotypes. Male and female (12.vii. [19]28) from Santa Catarina in perfect condition; female from Bahia with the forewings worn, the right one broken at the tip, as are both antennae. Female from 27.v.29 with the tips of the antennae broken, the rest in good condition. Remaining females in good condition.
Remarks. This species was described from two males and five females. Both males and four of the females are from Jaraguá, state of Santa Catarina, south Brazil. The remaining female is from Bahia. Both the male and female were illustrated by Zerny (1931b), and we chose the male as the lectotype to allow comparison with other species, given that males are usually more common than females, as reflected in the majority of the types being males. The female from Bahia has the red head spots characteristic of the species, but they are smaller than the spots of the other specimens and are partly hidden by the pronotum.
As mentioned by Zerny (1931b), Episcepsis melanoneura is closely related to E. venata Butler, 1877, the type species of the genus.
description: Published as part of Pinheiro, L. R. & Gaal-Haszler, S., 2015, Illustrated catalogue of Neotropical Ctenuchina, Euchromiina and Pericopina types (Lepidoptera, Erebidae, Arctiinae, Arctiini) described by Hans Zerny, with discussion on their taxonomic status, pp. 505-535 in Zootaxa 3925 (4) on page 515, DOI: 10.11646/zootaxa.3925.4.2, http://zenodo.org/record/240540
Philonthus pseudolus Smetana 1995
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Philonthus
Philonthus pseudolus

description: Philonthus pseudolus Smetana, 1995
Philonthus pseudolus Smetana, 1995: 283, Figs 408–414.
Two paratypes are deposited in NMPC (ex coll. L. Hro-
mádka):
PA*©A*´YPൾඌ (11 ♀): ‘ONT. Rondeau Pr. / Park end of / Marsh Trail 29. / V.85 A.Smetana [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // PARATYPE / Philonthus / pseudolus / A. Smetana 1993 / CNC No.21956 [p, yellow label]’.
Current status. Philonthus pseudolodes Smetana, 1996, see Hൾ*©MAN (2001b).
Comments. SMൾ*´ANA (1996) proposed the new substitute name Philonthus pseudolodes Smetana, 1996 for Philonthus pseudolus Smetana, 1995, a junior primary homonym of Philonthus pseudolus Last, 1989.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 380, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
Organizational strategy development for the pharmaceutical industry
Creators: name: Kim, Hyuk
Publisher: name: No Publisher Supplied
Year: 2010

description: This dissertation aims to develop a new direction, in stakeholder management terms, for the pharmaceutical industry to deal with its risks/challenges, particularly in relation to the access to essential, life-saving medicines, posed by its various stakeholders. The organizational strategy development framework of this dissertation is comprised of five phases. The first phase investigates the implications of the stakeholder management perspective for the organizational strategy development in terms of the pharmaceutical industry, examining the concepts, theories, and empirical evidences of extant studies.The second and third phases present a new analytical approach in stakeholder analysis terms, linking stakeholder analysis with organizational strategy development. The stakeholder analysis of this dissertation is performed by adopting two different types of the formal qualitative analysis - an event structure analysis and a qualitative comparative Boolean analysis -- examining 48 major global public health-related cases (which consist of 146 events) from 1987 to 2007. The stakeholder analysis examines: the key stakeholders of the pharmaceutical industry; the circumstances/conditions under which the pharmaceutical industry has put measures of stakeholder management into practice; and the types of the measures that have been adopted by the pharmaceutical industry to deal with its stakeholders in conjunction with the ability to gain access to essential, life-saving medicines.The fourth phase constructs an analogical reasoning model for the pharmaceutical industry in comparison with the food and beverage industry. In the last phase, a specific stakeholder management strategy for the pharmaceutical industry is suggested: i.e., the comprehensive, proactive, multi-stakeholder public-private partnership. This strategic option is developed based on the outcomes of the stakeholder analysis combined with those of the analogical reasoning model.The new strategic direction for the pharmaceutical industry suggested in this dissertation provides an integrated approach to the industry’s strategic decision making to satisfy the multiple types of stakeholders simultaneously. It is expected that this new organizational strategy for the pharmaceutical industry can be a useful tool to realize a comprehensive win-win situation: i.e., for the pharmaceutical industry in the stakeholder management terms and for its stakeholders in the access to essential, life-saving medicine terms.
An analysis of the effects of traditional versus alternative educational assessment programs on student attitudes and post secondary outcomes
Creators: name: Keeton, Vincent André
Publisher: name: No Publisher Supplied
Year: 2010

description: This dissertation examines the effects different types of assessments play on the post secondary lives of students graduating high school in Newark, New Jersey.  It is grounded in theories dealing with the impact of graduating via high-stakes versus alternative assessment programs.  Analyzing two quantitative databases, this study examines the differences in post secondary outcomes, perceptions and attitudes of those students graduating via the state mandated high stakes HSPA (High School Proficiency Assessment) examination and the alternative SRA (Special Review Assessment) examination.The data indicate that a majority of students tracked in this study graduate via the SRA as compared to the HSPA.  Analysis found that blacks and Latinos graduate more often via the SRA than whites and women graduate via the HSPA assessment program slightly more often than men. The data indicate that magnet school students graduate more often via the HSPA than traditional neighborhood comprehensive schools; HSPA graduates attend college at greater rates than do SRA graduates; SRA graduates are more likely to attend 2-year community colleges compared to HSPA graduates and are more likely to attend public schools and vocational/technical schools than HSPA graduates.  Multivariate analysis found that, controlling for other factors, women are more likely to go on to post-secondary study as compared to men, blacks are more likely to go on to post-secondary study as compared to whites and Hispanic/Latinos, women, blacks and Hispanic/Latinos are more likely to graduate SRA than whites and HSPA graduates and magnet school graduates are more likely to go on to post secondary study and attend 4-year colleges/universities than SRA graduates. Many educators and policy makers continue calls for elimination of the SRA.  As a significant percentage of urban "Abbott Districts" graduates exit high school via the SRA, this study provides evidence against such a policy direction. This study suggests that eliminating the SRA might result in many students dropping out. Given that almost half of the SRA graduates studied here attended some form of postsecondary educational institution, sound policy dictates that the assessment be strengthened, not eliminated.
title: Integrated logic circuit including impedance fault detection
Creators: name: Sloan, Mark D.
name: Rogers, William A.
name: Shoroff, Srihari
Publisher: name: United States Patent and Trademark Office
Year: 1995
Subjects: subject: G01R31/30
subject: 714/724
subject: 714/733
subject: 714/734

description: An integrated logic circuit according to the present invention includes a plurality of logic circuit elements, such as field effect transistors, for performing a combinational logic function, and at least one test controlled-impedance element for loading the logic circuit and causing a first digital output signal to be produced when the impedance of a logic circuit element under test is within a predetermined range and produce another digital output signal when the impedance of the logic circuit element under test is outside the predetermined range. The test controlled-impedance elements typically comprise field effect transistors and are sized in accordance with a series of constraints. The constraints are obtained by considering the operation of the circuit under various impedance fault conditions (high, low and intermediate) and deriving a series of size relationships between the impedance values of the logic circuit and test elements. The impedance faults capable of being detected include the conventional stuck-on (LIF) arid stuck-off (HIF) impedance faults and also intermediate impedance faults (IHIF, ILIF) caused by a too high or too low an impedance in a transistor's on- and off-state modes of operation, respectively.
Determinants of the mode of offshoring of services by large US corporations
Creators: name: Pore, Anand
Publisher: name: No Publisher Supplied
Year: 2010

description: This study explores the effects of service characteristics, firm capabilities, strategic motives and concerns on mode of offshoring of services of large US corporations. Firms could offshore services through a wide spectrum of modes ranging from i) complete internalization (foreign subsidiary), to ii) complete externalization (arms length transactions), or iii) intermediate modes (such as licensing, joint venture etc). Although, factors such as cost savings, time savings, host country incentives, access to skilled resources and markets may motivate firms to engage in offshoring of services; concerns regarding security/privacy of data, intellectual property rights, host country political/economic uncertainty, cultural distance between the host country and the home country and lack of partners/vendors in the host country may discourage firms from either offshoring services completely or may limit the choice of offshoring modes available to the firm in the host country. Also, factors related to the service such as strategic importance of the service to the firm, customization needs of the customer and use of proprietary technology in the production/performance of the service and firm capabilities may play a part in deciding the mode of offshoring. All these factors related to the service characteristics, firm capabilities, motives and concerns are used to build a model to explain the modal choice of offshoring of services of large US corporations. Survey data, regarding the above mentioned factors for firms involved in offshoring of services, was collected to empirically test the model.The model was tested using multinomial, binomial and ordinal regression. Results of the study support the influence of the strategic importance of the service, proprietary technology and cost savings motive on the mode of offshoring.  In addition, firm’s concerns regarding security/privacy of data, host country political/economic uncertainty, and lack of partners/vendors in the host country were also found to influence the offshoring mode. But, firm's motives of time savings, accessing host country skills and market and taking advantage of host country incentives were not found to influence the offshoring mode. Moreover, firm capabilities and firm's concerns over intellectual property protection and cultural distance were also not found to influence the mode of offshoring.
Episcepsis nereus Zerny 1931
Creators: name: Pinheiro, L. R.
name: Gaal-Haszler, S.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Arctiidae
Episcepsis
Episcepsis nereus

description: nereus Zerny, 1931
(Fig. 18)
Episcepsis nereus Zerny, 1931a: 248. Lectotype hereby designated, male, [BRAZIL, Pará, Santarém], Taperinha, with three labels: one printed label “Unt. Amaz. Taperinha b. Santarem 21–31.viii.27 Zerny”, “Auf Heliotropium indicum L.”, and “ Episcepsis nereus Zerny Type ♂”. Nine paralectotypes, all males. All with the same labels as the lectotype, differing only in date, except for one from the same date. The dates of the others are as follows: three males from “1– 10.viii.[19]27”; one from “ 11–20.vii. [19]27”; another from “ 11–20.viii. [19]27”; and three others from 21–31.vii. [19]27.
Current combination. Episcepsis nereus Zerny, 1931.
Condition of the types. Lectotype. Forewings somewhat rubbed. Paralectotypes. One of the males from 11–20.vii.1927 has the apex of forewings badly rubbed, almost without the white scales that characterise the species. One of the specimens from 21–31.vii.1927 has lost its abdomen. Another from the same date has lost its left antenna. All others have only minor rubbing on the forewings.
Remarks. This species was described from 12 syntypes, all from Fazenda Taperinha. The specimens collected in July and August are deposited at the NHMW. The remaining two could not be traced. Because they were collected by Hagmann, it was logical to think that they might be held at the Museu Paraense Emílio Goeldi, but William Overal, present curator of Lepidoptera of that institution, found no specimens with compatible labels.
The lectotype by present designation is the specimen here illustrated. In relation to the paralectotype, which bears exactly the same labels, it can be distinguished by having the wings slightly more worn, and by the position of the antennae.
description: Published as part of Pinheiro, L. R. & Gaal-Haszler, S., 2015, Illustrated catalogue of Neotropical Ctenuchina, Euchromiina and Pericopina types (Lepidoptera, Erebidae, Arctiinae, Arctiini) described by Hans Zerny, with discussion on their taxonomic status, pp. 505-535 in Zootaxa 3925 (4) on page 515, DOI: 10.11646/zootaxa.3925.4.2, http://zenodo.org/record/240540
Nondestructive evaluation of residual stresses in nanostructured coatings by synchotron radiation
Creators: name: Ahmedi, Nazia Ikram
Publisher: name: No Publisher Supplied
Year: 2010

description: This thesis presents a strain mapping in nanostructure Al2O3/TiO2 ceramic coatings on metallic Titanium substrates by synchrotron radiation. The mapping is obtained under various boundary conditions (tension/compression loads, four-point bending, etc.) and is accomplished using high energy (deeply penetrating) synchrotron white radiation with photon energies up to 200 keV to perform high precision x-ray diffraction on small volumes (1 µm to a few cm), which are then integrated into high resolution 3D maps of the strain fields. Strain mapping in conventional micro-size ceramic coatings are performed for comparison. The underlining structural and functional parameters in processing of these coatings, which result in dramatic improvements in their performance, are discussed. The thesis also presents mechanical properties such as elastic modulus, yield strength, etc., which are deduced from energy dispersive X-ray diffraction (EDXRD) strain mapping in conjunction with modeling.
Ceramidia pinguis Zerny 1931
Creators: name: Pinheiro, L. R.
name: Gaal-Haszler, S.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Arctiidae
Ceramidia
Ceramidia pinguis

description: pinguis Zerny, 1931
(Figs. 19 and 61)
Ceramidia pinguis Zerny, 1931b: 18 (Taf. 1, fig. 30). Holotype male, by monotypy: BOLIVIA, Coroico, 1400m (Fassl); with two labels: printed label “ Bolivia, Coroico, 1400m, Fassl” and handwritten label “ Ceramidia pinguis Zerny ♂ type ”.
Current combination. Antichloris pinguis (Zerny, 1931).
Condition of the type. Genitalia dissected (Fig. 54) and kept in plastic vial pinned with the specimen. The dissection was made from the terminal portion of the abdomen, so most of the specimen is intact. The type is in otherwise good condition excepting that the tips of the forewings are slightly rubbed.
Remarks. Field (1975) transferred this species to Antichloris Hübner, 1818, in the A. eriphia complex (Zygaena eriphia Fabricius, [1777] is the type species of Antichloris). This is the current combination, but a revision of this group is still pending.
description: Published as part of Pinheiro, L. R. & Gaal-Haszler, S., 2015, Illustrated catalogue of Neotropical Ctenuchina, Euchromiina and Pericopina types (Lepidoptera, Erebidae, Arctiinae, Arctiini) described by Hans Zerny, with discussion on their taxonomic status, pp. 505-535 in Zootaxa 3925 (4) on page 516, DOI: 10.11646/zootaxa.3925.4.2, http://zenodo.org/record/240540
title: Integrated circuit having clock-line control and method for testing same
Creators: name: Rogers, William A.
name: Baeg, Sanghyeon
Publisher: name: United States Patent and Trademark Office
Year: 1996
Subjects: subject: G01R31/31855
subject: 714/724
subject: 714/733
subject: 714/734

description: An integrated circuit includes a plurality of interconnected circuit modules having memory elements and logic elements therein. The modules collectively perform the operations of the integrated circuit. However, rather than testing the entire circuit and limiting the degree of fault coverage, individual modules can be tested on a module by module basis. To facilitate testing at the module level, the circuit includes a plurality of control cells connected to respective ones of the modules. Each of the control cells preferably includes a shift register latch for retaining a data signal corresponding to whether the respective module is to be sequentially tested or temporarily disabled. The control cells further comprise a pass-through transistor network for passing the system clock to one or more of the modules under test and for withholding the clock from the modules not under test. The method of the present invention includes steps for disabling one or more modules which are not under test and enabling those modules which are to be tested. The enabled modules are then tested sequentially, preferably using one or more outputs from the disabled modules. Testing of the integrated circuit occurs on a module by module basis until all modules are tested.
Ctenucha reimoseri Zerny 1912
Creators: name: Pinheiro, L. R.
name: Gaal-Haszler, S.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Arctiidae
Ctenucha
Ctenucha reimoseri

description: reimoseri Zerny, 1912
(Fig. 20)
Ctenucha reimoseri Zerny, 1912b: 124. Holotype female [by monotypy]: PARAGUAY, San Luis; with two labels: printed label “Reimoser, Paraguay, San Luis” and handwritten label “ Ctenucha reimoseri Zerny type ♀”.
Current combination. Ctenucha reimoseri Zerny, 1912.
Condition of the type. The left antenna is broken and the wings are slightly rubbed.
Remarks. Zerny (1912) thought that this species was allied to Ctenucha circe (Cramer, 1780). Even though this might seem a reasonable hypothesis judging by the figures of C. circe available in the literature (Cramer 1780, pl. 263, fig. D and pl. 264, fig. E; Draudt 1915, fig. 26 row d), the illustrations do not well match a syntype of C. circe that is deposited in the BMNH. In fact, judging from its habitus, C. circe is likely misplaced in Ctenucha. C. reimoseri, on the other hand, has an habitus sufficiently similar to Ctenucha virginica (Charpentier, 1830), senior synonym of C. latreillana Kirby, 1837 (type species of Ctenucha), that it is likely properly placed in that genus.
description: Published as part of Pinheiro, L. R. & Gaal-Haszler, S., 2015, Illustrated catalogue of Neotropical Ctenuchina, Euchromiina and Pericopina types (Lepidoptera, Erebidae, Arctiinae, Arctiini) described by Hans Zerny, with discussion on their taxonomic status, pp. 505-535 in Zootaxa 3925 (4) on page 516, DOI: 10.11646/zootaxa.3925.4.2, http://zenodo.org/record/240540
Philonthus psittacus Hromadka 2008
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Philonthus
Philonthus psittacus

description: Philonthus psittacus Hromádka, 2008
Philonthus (s. str.) psittacus Hromádka, 2008c: 221, Figs 34–38.
The holotype and four paratypes are deposited in NMPC
(ex coll. L. Hromádka):
HƟĿƟ*´YPൾ (): ‘ [p, green label] // ZAMBIA NC / 185 km S Mwinilunga / 6.12.2004 / Snížek & Tichý [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // HOLOTYPUS / PHILONTHUS (Philonthus) / psittacus sp. nov. / Hromádka, det. 2007 [p, orange label]’.
PA*©A*´YPൾඌ (3): ‘ [p, green label] // ZAMBIA NC / 185 km S Mwinilunga / 6.12.2004 / Snížek & Tichý [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // PARATYPUS / PHILONTHUS (Philonthus) / psittacus sp. nov. / Hromádka, det. 2007 [p, orange label]’.
PA*©A*´YPൾ ♀) (: ‘ ♀ [p, orange label] // ZAMBIA NC / 185 km S Mwinilunga / 6.12.2004 / Snížek & Tichý [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // PARATYPUS / PHILONTHUS (Philonthus) / psittacus sp. nov. / Hromádka, det. 2007 [p, orange label]’.
Current status. Valid species.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 380, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
title: Pole inserting robotic mechanism for accessing the interior of a harsh enclosure
Creators: name: Haas, Carl Michael
name: Sreenivasan, Sidlgata V.
name: Traver, Alfred Ellis
name: Saidi, Kamel Shawki
name: Seo, Jongwon
name: Greer, Richard Lael
Publisher: name: United States Patent and Trademark Office
Year: 1999
Subjects: subject: B25J9/06
subject: F23J1/00
subject: Y10S414/122
subject: 110/165R
subject: 110/105
subject: 110/185
subject: 110/191
subject: 110/193
subject: 110/233
subject: 414/23
subject: 414/909
subject: 432/75
subject: 901/6

description: A robotic mechanism which can be attached to a furnace hopper and includes a frame which supports a pole insertion mechanism for inserting a pole into a furnace hopper. The pole insertion mechanism is supported from the Fame by a gimbal and moves the pole axially. Hydraulic actuators rotate the pole insertion mechanism about the gimbal. A control system is associated with the mechanism and enables an operator to position the end of the pole within the hopper to remove clinkers.
Interaction of heated filaments with a blunt body in supersonic flow
Creators: name: Anderson, Kellie
Publisher: name: No Publisher Supplied
Year: 2010

description: Two computational studies are performed to examine the influence of energy deposition on a blunt body in supersonic flow.  The first objective is to determine the effect of increasing filament diameter on the efficiency and effectiveness of drag reduction to a blunt body. The second objective is to evaluate the influence of the energy filaments on the heat transfer to the blunt body. The energy deposition is modeled as a low density, high temperature filament that is injected in the freestream and interacts with the blunt body.  A code is written to solve the compressible Navier Stokes equations to evaluate these effects.
title: Methods for modulation and inhibition of telomerase
Creators: name: Chen, Shih-Fong
name: Windle, Bradford E.
name: Mamiya, Blain M.
name: Fletcher, Terace M.
name: Maine, Ira
name: Kerwin, Sean M.
name: Salazar, Miquel
name: Wajima, Makoto
Publisher: name: United States Patent and Trademark Office
Year: 1999
Subjects: subject: A61K31/7064
subject: A61K31/7068
subject: A61K31/7072
subject: A61K31/7076
subject: A61K31/708
subject: C07H19/14
subject: 514/43
subject: 514/45
subject: 514/48
subject: 536/23.1
subject: 536/24.5
subject: 536/26.23
subject: 536/26.26
subject: 536/26.7
subject: 536/27.8
subject: 536/27.81

description: It was found that normal human stem cells produce a regulated non-processive telomerase activity, while cancer cells produce a processive telomerase activity. Nucleotide analogs, such as 7-deaza-2'-deoxyquanosine-5'-triphosphate (7-deaza-dGTP) were found to be substrates for processive telomerase and incorporated into telomeric sequence. The incorporation of this nucleotide subsequently affected the processivity of telomerase, converting processive telomerase to non-processive telomerase. The incorporation of this nucleotide analogs was also found to inhibit formation of G-quartets by telomeric sequence. Other methods for converting cancer processive telomerase to the more benign non-processive telomerase include partially cleaving the telomerase RNA. The nucleoside analogs were found to be capable of a variety of activities including mediating allosteric-like inhibition of telomerase, premature termination and shortening of telomeric DNA, destabilization of telomeric structure and function and eventually cell death. Understanding the mechanisms of telomerase modulation by the 7-deazanucleotides has allowed the design of new telomerase inhibitors, modulators and agents for affecting telomere structure and function. These discoveries have application in the treatment of cancer.
Philonthus ptilopsis Hromadka 2014
Creators: name: Mikátová, Šárka
name: Macháčková, Lenka
name: Hájek, Jiří
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Philonthus
Philonthus ptilopsis

description: Philonthus ptilopsis Hromádka, 2014
Philonthus ptilopsis Hromádka, 2014j: 424, Figs 39–42.
The holotype is deposited in NMPC (general collection):
HƟĿƟ*´YPൾ (): ‘ TANZANIA / Mwanza / 11.x. 1969 / Ardö leg. [p] // ex coll. L. Hromádka / National Museum / Prague, Czech Republic [p] // HOLOTYPUS / PHILONTHUS (s. str.) / ptilopsis sp. nov. / Hromádka, det., 2013. [p, red label]’.
Current status. Valid species.
description: Published as part of Mikátová, Šárka, Macháčková, Lenka & Hájek, Jiří, 2020, Catalogue of type specimens of beetles (Coleoptera) deposited in the National Museum, Prague, Czech Republic, pp. 353-389 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 380, DOI: 10.37520/aemnp.2020.021, http://zenodo.org/record/3880030
Automated image-based detection and grading of lymphocytic infiltration in breast cancer histopathology
Creators: name: Basavanhally, Ajay
Publisher: name: No Publisher Supplied
Year: 2010

description: The identification of phenotypic changes in breast cancer (BC) histopathology is of significant clinical importance in predicting disease outcome and prescribing appropriate therapy. One such example is the presence of lymphocytic infiltration (LI) in histopathology, which has been correlated with a variety of prognoses and theragnoses (i.e. response to treatment) in BC patients. In this thesis work a computer-aided diagnosis (CADx) system is detailed for quantitatively measuring the extent of LI from hematoxylin and eosin (H & E) stained histopathology. The CADx system is subsequently applied to BC patients expressing the HER2 gene (HER2+ BC), where LI extent has been found to correlate with nodal metastasis and distant recurrence. Although LI may be graded qualitatively by BC pathologists, there is currently no quantitative and reproducible method for measuring LI extent in HER2+ BC histopathology. Hence, a CADx system that performs this task will potentially help clinicians predict disease outcome and allow them to make better therapy recommendations for HER2+ BC patients. The CADx methodology comprises three key steps. First, a combination of region-growing and Markov Random Field algorithms is used to detect individual lymphocyte nuclei and isolate areas of LI in digitized H & E stained histopathology images. The centers of individual detected lymphocytes are used as vertices to construct a series of graphs (Voronoi Diagram, Delaunay Triangulation, and Minimum Spanning Tree) and a total of 50 architectural features describing the spatial arrangement of lymphocytes are extracted from each image. By using Graph Embedding, a non-linear dimensionality reduction method, to project the high-dimensional feature vectors into a reduced 3D embedding space, it is possible to visualize the underlying manifold that represents the continuous nature of the LI phenotype. Over a set of 100 randomized cross-validation trials, a Support Vector Machine classifier shows that the architectural feature set distinguishes HER2+ BC histopathology samples containing high and low levels of LI with a classification accuracy greater than 90%.
title: Process for CO2/natural gas separation
Creators: name: Koros, William
name: Vu, De Q.
Publisher: name: United States Patent and Trademark Office
Year: 2001
Subjects: subject: B01D69/02
subject: B01D53/228
subject: B01D69/08
subject: B01D71/021
subject: B01D2257/504
subject: B01D2323/08
subject: Y02C10/10
subject: Y10S55/05
subject: 95/51
subject: 96/8
subject: 96/10

description: The invention includes a process for separating CO.sub.2 from natural gas including: contacting a mixture of CO.sub.2 and natural gas with a first side of a carbon membrane in a manner to cause a portion of the mixture to pass through the carbon membrane to a permeate side. The resulting mixture on the permeate side becomes enriched in CO.sub.2 over that of the mixture on the first side. The carbon membrane includes an asymmetric hollow filamentary carbon membrane, including a partial carbonization product of an asymmetric hollow filament including an aromatic imide polymer material. The carbon membrane is at least 95 weight percent carbon, and has a dense layer located in the outside surface portion of the hollow filamentary membrane and a porous base layer continued from the dense layer and located in the inside portion of the hollow filamentary membrane. The contacting step occurs at a pressure of at least about 200 psia.
Episcepsis rotundipennis Zerny 1931
Creators: name: Pinheiro, L. R.
name: Gaal-Haszler, S.
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Arctiidae
Episcepsis
Episcepsis rotundipennis

description: rotundipennis Zerny, 1931
(Fig. 21)
Episcepsis rotundipennis Zerny, 1931b: 16 (Taf. 1, fig. 17 and 18). Lectotype hereby designated, male, BOLIVIA, Rio Songo, 800m (Fassl), with two labels: printed label “ Bolivia, Rio Songo, 800m, Fassl.”, and handwritten label “ Episcepsis rotundipennis Zerny ♂ type ”. One paralectotype, female, also with two labels: printed label “ Bolivia, Coroico, 1400m, Fassl.”, and handwritten label “ Episcepsis rotundipennis Zerny ♀ type ”.
Current combination. Episcepsis rotundipennis Zerny, 1931.
Condition of the types. Lectotype. Wings rubbed. Left antenna broken. Midlegs missing. Paralectotype. Right hindwing with a small tear near apex.
Remarks. This species was described from the two above mentioned specimens. Zerny compared it to E. frances Dyar, 1910, a species from Mexico, which is indeed remarkably similar. Both species are close in habitus, and share the peculiar hindwing androconia found in the type species of the genus, E. venata.
description: Published as part of Pinheiro, L. R. & Gaal-Haszler, S., 2015, Illustrated catalogue of Neotropical Ctenuchina, Euchromiina and Pericopina types (Lepidoptera, Erebidae, Arctiinae, Arctiini) described by Hans Zerny, with discussion on their taxonomic status, pp. 505-535 in Zootaxa 3925 (4) on page 516, DOI: 10.11646/zootaxa.3925.4.2, http://zenodo.org/record/240540
Poly(ethylene glycol) hydrogels for sustained topical drug delivery to the eyes and skin
Creators: name: Anumolu, Siva Naga Sree Priya
Publisher: name: No Publisher Supplied
Year: 2010

description: Sulfur mustard (SM) is a potent chemical warfare agent that mainly affects the eyes, lungs and skin. Inflammatory cytokines and Matrix Metalloproteinase-9 (MMP-9) have been identified as potential therapeutic targets for SM-induced tissue damage since they quantitatively increase over time in response to SM exposure. Doxycycline is a tetracycline antibiotic with anti-inflammatory properties that acts by inhibiting MMP-9. Currently, neither doxycycline nor doxycycline delivery systems have been investigated for treatment of SM injuries.The objective of this thesis project is to design and fabricate sustained release topical doxycycline delivery systems and evaluate their wound healing efficacy. Fast forming hydrogels were prepared by crosslinking a poly(ethylene glycol) (PEG)-based polymer containing multiple thiol groups with different polymers or crosslinkers. The optical properties of the hydrogels were evaluated by spectrophotometry and the hydrogels that were transparent or close to transparent were chosen for drug delivery to the eye. Physicochemical properties of the hydrogels evaluated by rheometry and swelling kinetics show that the hydrogels have good mechanical strength with a low degree of swelling (<8%).In vitro release profiles of doxycycline-loaded hydrogels demonstrated biphasic release with an initial burst phase followed by a sustained phase. Permeation of doxycycline through vesicant wounded corneas was 2.5 to 3.4 fold higher than through unwounded corneas suggesting that the barrier function of the cornea is compromised after vesicant exposure. Doxycycline hydrogels showed a significant improvement in corneal epithelial healing compared to a similar dose of doxycycline solution in a vesicant-exposed rabbit corneal organ culture model. The model vesicant, nitrogen mustard (NM) showed dose and time dependent wound progression in SKH-1 mice. The permeability of NM-exposed skin (5 µmoles) to different molecular markers increased significantly compared to the control suggesting that stratum corneum does not act as a barrier for transdermal drug absorption after vesicant exposure. From histology analyses, it is evident that doxycycline hydrogel treated groups showed significant wound healing efficacy compared to untreated or placebo hydrogel treated groups. In summary, in situ forming topical doxycycline-loaded PEG hydrogels showed superior wound healing efficacy offering a potential therapeutic option for mustard injuries in the eye and skin.
Polymeric nanospheres for skin penetration enhancement
Creators: name: Batheja, Priya B.
Publisher: name: No Publisher Supplied
Year: 2010

description: Research and development in the field of topical and transdermal delivery has been particularly challenging due to the tough penetration barrier provided by the stratum corneum, the superficial skin layer. Nano-sized vesicles can potentially act as carriers to skin layers without causing the toxicity and irritation associated with chemical and physical skin penetration enhancers. In this study we have characterized the skin penetration potential of polymeric nanospheres made from amphiphilic ABA-triblock co-polymers that are biocompatible, biodegradable and bind efficiently to hydrophobic molecules. We evaluated the delivery of hydrophobic and poorly water soluble compounds via these nanospheres into different skin layers and found significant enhancement in their delivery to the epidermal-dermal junction and to the dermis. Thus, these nanospheres have tremendous potential for targeting diseases such as acne, psoriasis and eczema that have their origins in these layers. Formulation of the nanospheres in hydrophilic gels, alone and in combination with a chemical skin penetration enhancer significantly increased the penetration of complexed molecules in vitro in human skin and in vivo in porcine skin.  We also evaluated the delivery profiles of these nanospheres in a bioengineered Human Skin Equivalent (HSE). The full thickness HSE was developed from a combination of human derived cells and extra-cellular components and cultured with a novel media cocktail to strengthen the permeability barrier. The HSE was characterized for the permeability profiles of agents with differing physiochemical properties and was found to be more permeable than human skin, but similar to the commercially available skin equivalent EpidermFT®.  The HSE also served as an effective model for evaluation of phototoxicity of topically applied agents, and was able to correctly predict the phototoxic potential of compounds when evaluated against a validated in vitro cell-based method.  When used for evaluation of the skin delivery potential of nanosphere formulations, the penetration enhancement ratios in the HSE were similar to those obtained in human skin and porcine skin, although the amount and depth of skin penetration of compounds was different. Thus, despite a weaker permeability barrier, the HSE can serve as a reproducible model for pre-screening of the skin delivery properties of formulations.