cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Huygens' envelope principle in Finsler spaces and analogue gravity
Creators: name: Dehkordi, Hengameh R.
name: Saa, Alberto
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 53B40 53B50 83C57 83C80

description: We extend to the $n$-dimensional case a recent theorem establishing the validity of the Huygens' envelope principle for wavefronts in Finsler spaces. Our results have direct applications in analogue gravity models, for which the Fermat's principle of least time naturally gives origin to an underlying Finslerian geometry. For the sake of illustration, we consider two explicit examples motivated by recent experimental results: surface waves in flumes and vortices. For both examples, we have distinctive directional spacetime structures, namely horizons and ergospheres, respectively. We show that both structures are associated with certain directional divergences in the underlying Finslerian (Randers) geometry. Our results show that Finsler geometry may provide a fresh view on the causal structure of spacetime, not only in analogue models but also for General Relativity.
description: 17 pages, 3 figures. Final version accepted for publication in CQG. Animations in Supplementary Material available at http://vigo.ime.unicamp.br/Huygens/
Limacia Muller 1781
Creators: name: Vallès, Yvonne
name: Valdés, Ángel
name: Ortea, Jesús
Publisher: name: Zenodo
Year: 2000
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Polyceridae
Limacia

description: Genus Limacia Müller, 1781
TYPE SPECIES. — Doris clavigera Müller, 1776
REMARKS
MacFarland (1905) introduced the genus Laila MacFarland, 1905, based on Laila cockerelli MacFarland, 1905, as an “allied” to the genera Triopha Johnston, 1838 and Issa Bergh, 1880, but he did not refer to the genus Limacia Müller, 1781. The description of L. cockerelli was later completed with drawings of the radula and the animal in the living form (MacFarland 1966). Laila janssi Bertsch & Ferreira, 1974, presents similar morphological characteristics as L. cockerelli, differing on the colour pattern and in some radular features such as a smaller number of teeth rows, a rougher rachidian plate texture and some variations on the shape of the outer lateral teeth (Bertsch & Ferreira 1974).
The genus Laila has the same morphological characteristics as the genus Limacia: pallial margin with numerous club-shaped papillae; presence of tubercles on the notum; veil appendages canaliculated; retractile rhinophores; branchial leaves non retractile; two inner lateral teeth hook-shaped, the innermost being thinner and longer than the outermost, and many outer lateral teeth quadrangularshaped. Laila and Limacia only differ in the fact that Limacia clavigera Müller, 1776, lacks a rachidian plate in the radula, which is present in both L. cockerelli and L. janssi. Since most of the morphological features of Laila and Limacia are very similar, just the presence of rachidian plate in the radula of Laila does not seem to be enough to consider Laila as a different genus. Therefore both genera are here regarded as synonyms, with Limacia Müller, 1781 having priority. This idea was already proposed by Ortea et al. (1989).
description: Published as part of Vallès, Yvonne, Valdés, Ángel & Ortea, Jesús, 2000, On the phanerobranch dorids of Angola (Mollusca, Nudibranchia): a crossroads of temperate and tropical species, pp. 15-31 in Zoosystema 22 (1) on page 20, DOI: 10.5281/zenodo.5398985
The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of Its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly
Creators: name: Tripathy, Ashutosh
name: Tarricone, Cataldo
name: Choi, Won Chan
name: Derewenda, Urszula
name: Derewenda, Zygmunt S.
name: Lukasik, Steve
name: Cafiso, David S.
name: Perrina, Franco
name: Cooper, David R.
name: Musacchio, Andrea
name: Kim, Myung Hee
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Ndel1 and Nde1 are homologous and evolutionarily conserved proteins, with critical roles in cell division, neuronal migration, and other physiological phenomena. These functions are dependent on their interactions with the retrograde microtubule motor dynein and with its regulator Lis1--a product of the causal gene for isolated lissencephaly sequence (ILS) and Miller-Dieker lissencephaly. The molecular basis of the interactions of Ndel1 and Nde1 with Lis1 is not known. Here, we present a crystallographic study of two fragments of the coiled-coil domain of Ndel1, one of which reveals contiguous high-quality electron density for residues 10-166, the longest such structure reported by X-ray diffraction at high resolution. Together with complementary solution studies, our structures reveal how the Ndel1 coiled coil forms a stable parallel homodimer and suggest mechanisms by which the Lis1-interacting domain can be regulated to maintain a conformation in which two supercoiled alpha helices cooperatively bind to a Lis1 homodimer.
Exome Sequencing Identifies Mutations in CCDC114 as a Cause of Primary Ciliary Dyskinesia
Creators: name: Ostrowski, Lawrence E.
name: Zariwala, Maimoona A.
name: Carson, Johnny L.
name: Rosenfeld, Margaret
name: Davis, Stephanie D.
name: Leigh, Margaret W.
name: Bamshad, Michael J.
name: Dell, Sharon D.
name: Milla, Carlos E.
name: Ferkol, Thomas W.
name: Yin, Weining
name: Sagel, Scott D.
name: Hazucha, Milan J.
name: Turner, Emily H.
name: Shendure, Jay
name: Lewis, Alexandra P.
name: Berg, Jonathan S.
name: Knowles, Michael R.
name: Nickerson, Deborah A.
name: Huang, Lu
name: Olivier, Kenneth N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Primary ciliary dyskinesia (PCD) is a genetically heterogeneous, autosomal-recessive disorder, characterized by oto-sino-pulmonary disease and situs abnormalities. PCD-causing mutations have been identified in 14 genes, but they collectively account for only ∼60% of all PCD. To identify mutations that cause PCD, we performed exome sequencing on six unrelated probands with ciliary outer dynein arm (ODA) defects. Mutations in CCDC114, an ortholog of the Chlamydomonas reinhardtii motility gene DCC2, were identified in a family with two affected siblings. Sanger sequencing of 67 additional individuals with PCD with ODA defects from 58 families revealed CCDC114 mutations in 4 individuals in 3 families. All 6 individuals with CCDC114 mutations had characteristic oto-sino-pulmonary disease, but none had situs abnormalities. In the remaining 5 individuals with PCD who underwent exome sequencing, we identified mutations in two genes (DNAI2, DNAH5) known to cause PCD, including an Ashkenazi Jewish founder mutation in DNAI2. These results revealed that mutations in CCDC114 are a cause of ciliary dysmotility and PCD and further demonstrate the utility of exome sequencing to identify genetic causes in heterogeneous recessive disorders.
Neobuthus eritreaensis Lowe & Kovarik 2016
Creators: name: Kovařík, František
name: Lowe, Graeme
name: Awale, Ahmed Ibrahim
name: Elmi, Hassan Sh Abdirahman
name: Abdi, Ali
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Scorpiones
Buthidae
Neobuthus
Neobuthus eritreaensis

description: Neobuthus eritreaensis Lowe & Kovařík, 2016
(Figs. 408, 438, Table 5)
 Neobuthus eritreaensis Lowe & Kovařík, 2016: 14–26, figs. 43–95, 97, 151–153, 159, 161, tables 2, 4–5.
 TYPE LOCALITY AND TYPE REPOSITORY. Eritrea, near Massawa, 15°36'58.7"N 39°22'32.8"E, 74 m a.s.l.; FKCP.
 TYPE MATERIAL. Eritrea, near Massawa, 15°36'58.7"N 39°22'32.8"E, 74 m a.s.l. (Locality No. 15 EI, fig. 97 in Lowe & Kovařík, 2016: 25), 1♂ (holotype) 4♀1♀ im. (paratypes), FKCP, 1♂ 1♀ (paratypes), GLPC, 4.XI. 2015, leg. F. Kovařík (UV detection); near Massawa, 15°36'55" 39°24'22"E, 30 m a.s.l., (Locality No. 15 EK), 2♂ 1♀ im. (paratypes), FKCP, 8.XI.2015, leg. F. Kovařík (UV detection).
 EMENDED DIAGNOSIS. Total length 17–18 mm (males), 26–32 mm (females); carapace with area between anterior median carinae partially fuscous; tergites with 3 dark stripes, median stripe flanked on either side by broad longitudinal yellow bands that may be broken by fuscosity extending across anterior tergites; trichobothrium d 2 of pedipalp femur usually absent, d 2 of pedipalp patella present. pedipalp relatively slender, males with femur L/ W 2.44 –2.53, patella L/ W 2.47 –2.55, chela L/ W 4.79 –5.06; chela movable finger with 6 subrows of primary denticles, 3–4 external accessory denticles flanking proximal end of each subrow; dorsoexternal and ventroexternal carinae on pedipalp patella in female absent; posterior margins of tergites without or with 1–2 macrosetae; pedipalps, legs, metasoma and telson with very short, stout macrosetae in males, long, fine setae in females; males with coxae and sternites III– VI densely, finely granular, sternite VII densely, finely granular without carinae or 2 vestigial median carinae; females with sternites III– VI smooth, sternite VII finely granular with 4 granulated carinae; metasoma I–III with median lateral carinae present in female, absent in male; lateral surfaces of metasoma I–IV densely granulated in both sexes; lateral surface of metasoma V in males densely granulated, with granules separated; tarsi with relatively sparse setation, leg III of adults with 13–20 ventral macrosetae on telotarsus; pectine teeth: 19–21 (males), 15–18 (females).
description: Published as part of Kovařík, František, Lowe, Graeme, Awale, Ahmed Ibrahim, Elmi, Hassan Sh Abdirahman & Abdi, Ali, 2018, Scorpions of the Horn of Africa (Arachnida, Scorpiones). Part XVII. Revision of Neobuthus, with description of seven new species from Ethiopia, Kenya and Somaliland (Buthidae), pp. 1-82 in Euscorpius 271 on page 27
Interference and Interaction in Multiwall Carbon Nanotubes
Creators: name: Schonenberger, C.
name: Bachtold, A.
name: Strunk, C.
name: Salvetat, J. -P.
name: Forro, L.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report equilibrium electric resistance R and tunneling spectroscopy dI/dV measurements obtained on single multiwall nanotubes contacted by four metallic Au fingers from above. At low temperature quantum interference phenomena dominate the magnetoresistance. The phase-coherence and elastic-scattering lengths are deduced. Because the latter is of order of the circumference of the nanotubes, transport is quasi-ballistic. This result is supported by a dI/dV spectrum which is in good agreement with the density-of-states (DOS) due to the one-dimensional subbands expected for a perfect single-wall tube. As a function of temperature T the resistance increases on decreasing T and saturates at approx. 1-10 K for all measured nanotubes. R(T) cannot be related to the energy-dependent DOS of graphene but is mainly caused by interaction and interference effects. On a relatively small voltage scale of order 10 meV, a pseudogap is observed in dI/dV which agrees with Luttinger-Liquid theories for nanotubes. Because we have used quantum diffusion based on Fermi-Liquid as well as Luttinger-Liquid theory in trying to understand our results, a large fraction of this paper is devoted to a careful discussion of all our results.
description: 14 pages (twocolumn), 8 figures
Το Μάθημα των Θρησκευτικών στη Δημόσια Εκπαίδευση: ένα Μάθημα Θέσεων, Στοχασμού και Ερμηνείας
Creators: name: Stogiannidis, Athanasios
Publisher: name: Synthesis
Year: 2016
Subjects: Μάθημα των Θρησκευτικών; Δημόσια Εκπαίδευση; Αναλυτικά Προγράμματα του Μαθήματος των Θρησκευτικών; Ανάπτυξη της Θρησκευτικής Συνείδησης των Μαθητών

description: Synthesis, Vol 5, No 1
Thermal expansion and the equation of state of Ir and Rh
Creators: name: Katsnelson, M. I.
name: Sigalas, M.
name: Trefilov, A. V.
name: Khromov, K. Yu.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The simplest anharmonic characteristics of Ir and Rh are discussed in the framework of a previously developed simple pseudopotential model which describes the elastic moduli, phonon spectra and the lattice heat capacity in the harmonic approximation of these metals succesfully. The microscopic Gruneisen parameters, the dependences of the elastic moduli on pressure, the coefficient of thermal expansion and the equations of state at the finite temperatures have been calculated. The ab initio calculations of the energy-band structure and the equation of state for Ir at T=0 have been done to test the model for adequacy at high pressures. The values of different contributions (zero-point oscillations, quasiharmonic, etc.) in the considered thermodynamic characteristics of Ir and Rh are discussed.
description: 12 pages, 11 figures, LaTeX
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
Creators: name: Durda, Peter
name: Ruderfer, Douglas
name: Jun, Goo
name: Zhang, Ji
name: Li, Yun
name: Lange, Leslie A.
name: Lindgren, Cecilia
name: Gaulton, Kyle
name: Flannick, Jason
name: Locke, Adam
name: Peloso, Gina
name: Xue, Chenyi
name: Holmen, Oddgeir L.
name: Turner, Emily H.
name: Tang, Zheng-Zheng
name: Auer, Paul
name: Smith, Joshua D.
name: Manning, Alisa
name: Li, Kuo-ping
name: Bizon, Chris
name: Rivas, Manuel A.
name: Zhang, He
name: Kang, Hyun Min
name: Schmidt, Ellen M.
name: Hu, Youna
name: Stahl, Eli A.
name: Lange, Ethan M.
name: Fuchsberger, Christian
name: Sim, Xueling
name: Gottesman, Omri
name: Duan, Qing
name: Lu, Yingchang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs) have identified 157 variants associated with lipid levels but are not well suited to assess the impact of rare and low-frequency variants. To determine whether rare or low-frequency coding variants are associated with LDL-C, we exome sequenced 2,005 individuals, including 554 individuals selected for extreme LDL-C (>98th or <2nd percentile). Follow-up analyses included sequencing of 1,302 additional individuals and genotype-based analysis of 52,221 individuals. We observed significant evidence of association between LDL-C and the burden of rare or low-frequency variants in PNPLA5, encoding a phospholipase-domain-containing protein, and both known and previously unidentified variants in PCSK9, LDLR and APOB, three known lipid-related genes. The effect sizes for the burden of rare variants for each associated gene were substantially higher than those observed for individual SNPs identified from GWASs. We replicated the PNPLA5 signal in an independent large-scale sequencing study of 2,084 individuals. In conclusion, this large whole-exome-sequencing study for LDL-C identified a gene not known to be implicated in LDL-C and provides unique insight into the design and analysis of similar experiments.
Kurūbā, Kurūmbā and Kuṁḷbī
Creators: name: RODRIGUES, TENSING CARLOS
Publisher: name: figshare
Year: 2019
Subjects: subject: History
subject: Anthropology
subject: FOS: Sociology
subject: Archaeology
subject: Sociology
subject: Geography

description: Taking into account the entire discussion up to now, it appears that the range of communities under all the denominations considered above - kuṁḷbī, kunbi, kurmi, kudubi, kurni, kanbi, and possibly kurūbā and kurūmbā of the Nilgiri Hills and Wayanad Plateau - have a common or similar origin. It is possible that they owe their origin to a single community at some point in history. But we cannot come to such a conclusion without further evidence.
Pemphigoid Antibody Mediated Attachment of Peripheral Blood Leukocytes at the Dermal-Epidermal Junction of Human Skin
Creators: name: Carlo, Jaime R.
name: Gammon, Walter R.
name: Wheeler, Clayton E.
name: Sams, Wiley M.
name: Lewis, Daniel M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1980

description: It has been proposed that cutaneous inflammation and blister formation in bullous pemphigoid is caused by antibodies to the cutaneous basement membrane zone which activate complement, thereby, attracting leukocytes to the dermal-epidermal junction There is, however, no functional evidence which supports a role for pemphigoid antibodies in complement activation or leukocyte activity in skin. This study describes the in vitro attachment of human peripheral blood leukocytes to the dermal-epidermal junction of cryostat skin sections treated with 9/13 pemphigoid sera containing antibodies to the cutaneous basement membrane zone. A requirement for complement in the reaction was supported by the findings that only complement-fixing pemphigoid sera mediated the leukocyte response, a strong correlation existed between complement-fixation titers and leukocyte attachment titers and only leukocytes suspended in fresh serum but not buffer or heat in activated serum attached at the junction. A requirement for antibody was supported by the observation that IgG fractions of 4 pemphigoid sera were as effective as whole sera in mediating leukocyte attachment. The leukocyte response was shown to be specific for complement-fixing pemphigoid sera since it was not observed with non-complement-fixing sera or sera from 15 normal human and 22 non-pemphigoid disease controls. This study offers functional evidence for an interaction between pemphigoid anti-body, complement and leukocytes in the immunopathogenesis of bullous pemphigoid and demonstrates that complement fixing antibasement membrane zone antibodies may be important in initiating the cellular inflammatory events observed near the dermal-epidermal junction in viva.
$s$-wave scattering lengths for the $^7$Be+p system from an $\textit{R}$-matrix analysis
Creators: name: Paneru, S. N.
name: Brune, C. R.
name: Giri, R.
name: Livesay, R. J.
name: Greife, U.
name: Blackmon, J. C.
name: Bardayan, D. W.
name: Chipps, K. A.
name: Davids, B.
name: Connolly, D. S.
name: Chae, K. Y.
name: Champagne, A. E.
name: Deibel, C.
name: Jones, K. L.
name: Johnson, M. S.
name: Kozub, R. L.
name: Ma, Z.
name: Nesaraja, C. D.
name: Pain, S. D.
name: Sarazin, F.
name: Shriner, J. F.
name: Stracener, D. W.
name: Smith, M. S.
name: Thomas, J. S.
name: Visser, D. W.
name: Wrede, C.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The astrophysical $S$-factor for the radiative proton capture reaction on $^7$Be ($S_{17}$) at low energies is affected by the $s$-wave scattering lengths. We report the measurement of elastic and inelastic scattering cross sections for the $^7$Be+p system in the center-of-mass energy range 0.474 - 2.740 MeV and center-of-mass angular range of 70$^\circ$- 150$^\circ$. A radioactive $^7$Be beam produced at Oak Ridge National Laboratory's (ORNL) Holifield Radioactive Ion Beam Facility was accelerated and bombarded a thin polypropylene (CH$_{2}$)$_\text n$ target. Scattered ions were detected in the segmented Silicon Detector Array. Using an $\textit{R}$-matrix analysis of ORNL and Louvain-la-Neuve cross section data, the $s$-wave scattering lengths for channel spins 1 and 2 were determined to be 17.34$^{+1.11}_{-1.33}$ and -3.18$^{+0.55}_{-0.50}$ fm, respectively. The uncertainty in the $s$-wave scattering lengths reported in this work is smaller by a factor of 5-8 compared to the previous measurement, which may reduce the overall uncertainty in $S_{17}$ at zero energy. The level structure of $^8$B is discussed based upon the results from this work. Evidence for the existence of 0$^+$ and 2$^+$ levels in $^8$B at 1.9 and 2.21 MeV, respectively, is observed.
Neobuthus ferrugineus
Creators: name: Kovařík, František
name: Lowe, Graeme
name: Awale, Ahmed Ibrahim
name: Elmi, Hassan Sh Abdirahman
name: Abdi, Ali
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Scorpiones
Buthidae
Neobuthus
Neobuthus ferrugineus

description: Neobuthus ferrugineus (Kraepelin, 1898)
(Figs. 182–212, 410, 438, Table 1)
 Butheolus ferrugineus Kraepelin, 1898: 43; Fet & Lowe, 2000: 88; Lourenço, 2001: 177, fig. 12; Kovařík, 2003: 137 (in part); Kovařík, 2004: 4 (in part); Lourenço, 2005: 27, fig. 31; Lourenço & Qi, 2006: 91–93.
 Neobuthus ferrugineus: Kraepelin, 1903: 563–564; Vachon, 1980: 255; Kovařík & Lowe, 2012: 3–7, figs. 60–61, 72 (in part).
 TYPE LOCALITY AND TYPE DEPOSITORY. Djibouti, Gulf of Aden, Tadjura Bay, ZMUH.
 TYPE MATERIAL EXAMINED. Djibouti, Gulf of Aden, Tadjura Bay, 1♂ (holotype, Figs. 213–214), ZMUH.
 ADDITIONAL MATERIAL EXAMINED. Djibouti, Barra Yer (Petit Barre), 11°18'33.56"N 42°42'39.17"E, 585 m a.s.l., I. 2017, 1♂ 2♀, FKCP, 1♂ 1♀, GLPC, leg. R. Štarha.
E MENDED DIAGNOSIS. Total length 19–21 mm (male), 25–27 mm (female); carapace with area between anterior median carinae orange to partially fuscous; tergites with 3 dark stripes, median stripe flanked on either side by broad longitudinal yellow bands that may be broken by fuscosity extending across anterior tergites; pedipalp relatively slender, males with femur L/ W 2.28 –2.48, patella L/ W 2.40 –2.46, chela L/ W 4.75 –5.95; chela movable finger with 6 subrows of primary denticles, 3–4 external accessory denticles flanking proximal end of each subrow; dorsoexternal carina on pedipalp patella in female weakly indicated, ventroexternal carina absent; posterior margins of tergites without or with 1–2 pairs of macrosetae; pedipalps, legs, metasoma and telson with very short, stout macrosetae in males, and long, fine setae in females; males with sternite VII densely granular without carinae or 2 vestigial median carinae; females with sternites III– VI smooth, sternite VII finely granular with 4 vestigial carinae; metasoma I–III with median lateral carinae present in female, absent in male; lateral surfaces of metasoma I–IV densely granulated in male and smooth in female; lateral surface of metasoma V in males densely granulated, with granules separated; tarsi with relatively sparse setation, leg III of adults with 14–18 ventral macrosetae on telotarsus; pectine teeth: 18–21 (males), 16–18 (females).
description: Published as part of Kovařík, František, Lowe, Graeme, Awale, Ahmed Ibrahim, Elmi, Hassan Sh Abdirahman & Abdi, Ali, 2018, Scorpions of the Horn of Africa (Arachnida, Scorpiones). Part XVII. Revision of Neobuthus, with description of seven new species from Ethiopia, Kenya and Somaliland (Buthidae), pp. 1-82 in Euscorpius 271 on page 37
Rod motifs in neutron scattering in spin ice
Creators: name: Castelnovo, Claudio
name: Moessner, Roderich
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In classical and quantum spin ice, rod-like features appear in the neutron scattering structure factor when the pinchpoints characteristic of classical spin ice get washed out. We show that these features do not indicate the absence of spin correlations between planes perpendicular to the rods. Rather, they arise because unpolarised neutron scattering is largely insensitive to the three-dimensional correlations which are present throughout. We present two very simple models which exhibit a pristine incarnation of such scattering rods. This provides a physical picture for their appearance, elucidates the role played by monopole excitations and identifies conditions conducive to their observation.
description: (5 pages, 3 figures)
Epidermal-dermal Interactions in Adult Skin
Creators: name: Briggaman, Robert A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1982

description: Epidermal-dermal interactions are important determinants of embryonic development in skin. This review examines the role of such epidermal-dermal interactions in the conservation of epithelial specificity in adult skin. The basic epidermal keratinization program as defined as a proliferative basal cell population, orderly stratified cytodifferentiation of the cells and production of stratum corneum can be expressed by adult epidermis without the continued presence of a specific dermis. This is evidenced by the ability of epidermis to differentiate fully in association with nondermal connective tissues. Several other epithelia including cornea and esophagus express their specific differentiative characteristics without the continued presence of specific connective tissue. On the other hand, certain regional epithelial specificities in adult skin may be determined by the dermis. These regional epidermal specificities involve alterations in epidermal thickness, size of epidermal compartments including the stratum corneum, and the folding pattern at the epidermal-dermal interface. Possible mechanisms by which dermis could control these regional characteristics are discussed. Epidermal-dermal recombination techniques have been used to define the site of gene action in a variety of inherited skin abnormalities in animals. Similar studies are reported utilizing adult human skin in long-term cultivation on nude athymic mice. The abnormal gene in lamellar ichthyosis exerts its effect directly on the epidermis. Generalized exfoliative psoriasis was also studied by recombination techniques. Both epidermis and dermis were required for the maintenance of psoriatic morphology, suggesting a complex polygenic mechanism or one involving both genetic and environmental factors.
The Finite Temperature Mott Transition in the Hubbard Model in Infinite Dimensions
Creators: name: Rozenberg, Marcelo J.
name: Chitra, R.
name: Kotliar, G.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the second order finite temperature Mott transition point in the fully frustrated Hubbard model at half filling, within Dynamical Mean Field Theory. Using quantum Monte Carlo simulations we show the existence of a finite temperature second order critical point by explicitly demonstrating the existence of a divergent susceptibility as well as by finding coexistence in the low temperature phase. We determine the location of the finite temperature Mott critical point in the (U,T) plane. Our study verifies and quantifies a scenario for the Mott transition proposed in earlier studies (Reviews of Modern Physics 68, 13, 1996) of this problem.
description: 4 RevTex pages, uses epsf, 2 figures
Complement-Activating Immune Deposits in Systemic Lupus Erythematosus Skin
Creators: name: Henley, Nancy
name: Merritt, Carolyn C.
name: Ray Gammon, W.
name: Henke, David C.
name: Robinson, Ted
name: DeAngelo, Laura
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1983

description: Immune deposits at the cutaneous basement membrane zone are a characteristic feature of systemic lupus erythematosus. Previous studies using immunofluorescent methods to detect complement components have provided evidence that some deposits contain immune complexes capable of activating complement. However, this important biologic property of complexes has not been detected or measured using functional assays, and it has not been determined whether immune deposits can activate complement at the basement membrane zone. In this study immune deposits in biopsies of lupus skin have been examined using direct immunofluorescence for the third component of complement (C3) to detect complement deposited in vivo. In addition, the deposits have been studied using the leukocyte attachment assay and indirect C3 binding immunofluorescence to detect and measure complement activation at the basement membrane zone in vitro. The results show that complement activation occurs at the basement membrane in some but not all lupus skin containing immunoglobulin deposits, that deposits differ quantitatively in their ability to activate complement, and that direct C3 immunofluorescence is a relatively insensitive method for detecting complement-activating complexes. The results provide functional evidence suggesting that immune deposits in some lupus skin are complement-activating complexes and potentially capable of activating complement at the basement membrane in vivo. Furthermore, the results suggest functional assays for evaluating complement-activating complexes may be valuable supplements to immunofluorescence in exploring the relationship between immune deposits and systemic and cutaneous disease.
Temperature dependent spatial oscillations in the correlations of the XXZ spin chain
Creators: name: Fabricius, Klaus
name: Klümper, Andreas
name: McCoy, Barry M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the correlation $$ for the XXZ chain in the massless attractive (ferromagnetic) region at positive temperatures by means of a numerical study of the quantum transfer matrix. We find that there is a range of temperature where the behavior of the correlation for large separations is oscillatory with an incommensurate period which depends on temperature.
description: 4 pages, REVTEX, 6 tables
Three-step alternating iterations for index one matrices
Creators: name: Nandi, Ashish Kumar
name: Sahoo, Jajati Keshari
name: Mishra, Debasisha
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Iterative methods based on matrix splittings are useful in solving large sparse linear systems. In this direction, proper splittings and its several extensions are used to deal with singular and rectangular linear systems. In this article, we introduce a new iteration scheme called three-step alternating iterations using proper splittings and group inverses to find an approximate solution of singular linear systems, iteratively. A preconditioned alternating iterative scheme is also proposed to relax some sufficient conditions and to obtain faster convergence as well. We then show that our scheme converges faster than the existing one. The theoretical findings are then validated numerically.
Differentiating Anti-Lamina Lucida and Anti-Sublamina Densa Anti-BMZ Antibodies by Indirect Immunofluorescence on 1.0 M Sodium Chloride-Separated Skin
Creators: name: Ray Gammon, W.
name: Briggaman, Robert A.
name: Wheeler, Clayton E.
name: Inman, Alfred O.
name: Queen, Laurinda L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: L'immunofluorescence indirecte sur la peau séparée est une méthode fiable pour différencier les anticorps contre la lame transparente et les anticorps contre la sous-lame dense des maladies bulleuses et la différenciation entre les anticorps est essentielle pour un diagnostic exact chez certains malades. Les anticorps contre la lame transparente dans la pemphigoïde bulleuse peuvent présenter plusieurs spécificités.
Molecular Characterization of the Ro/SS-A Autoantigens
Creators: name: Sontheimer, Richard D.
name: McCauliffe, Daniel P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: AbstractMolecular techniques have recently revealed that there are several immunologically distinct Ro/SS-A antigens. Three genes encoding putative Ro/SS-A protein antigens with calculated masses of 46, 52, and 60 kD have been isolated. The encoded amino acid sequence of each is quite dissimilar. The 46-kD antigen is calreticulin (CR), a highly conserved calcium-binding protein that resides predominately in the endoplasmic reticulum where it may be involved in protein assembly. Although CR has recently been confirmed to be a new human rheumatic disease-associated autoantigen, its relationship to the other components of the Ro/SS-A ribonucleoprotein has become somewhat controversial owing predominately to the fact that recombinant forms of calreticulin have not displayed the same pattern of autoantibody reactivity possesse by the native form of this protein.The 52-kD antigen most likely resides in the nucleus and may be involved in the regulation of gene expression. The cellular location and function of the 60-kD antigen is uncertain but studies indicate that it is a RNA-binding protein.The 46- and 60-kD antigens share homology with foreign polypeptides, suggesting that an immune response initially directed against a foreign protein may give rise to the autoimmune response directed at cross-reacting self proteins.
Hailey-Hailey Disease Keratinocytes: Normal Assembly of Cell-Cell Junctions In Vitro
Creators: name: Cronce, Donna J.
name: Banes, Albert J.
name: Briggaman, Robert A.
name: O'Keefe, Edward J.
name: Cooley, Jerry E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: The blisters in the inherited disorder, Hailey-Hailey disease, may be caused by defective epidermal junctional complexes. We evaluated these structural complexes in vivo and in vitro. We induced a vesicular lesion in the apparently normal skin of a patient with Hailey-Hailey disease and studied a biopsy of this lesion by transmission electron microscopy. To determine whether acantholysis was related to a defect in the number or assembly of intercellular junctions, we cultured Hailey-Hailey disease keratinocytes in medium containing 0.1 mM Ca2+ and increased the [Ca2+] to 1.1 mM in order to induce assembly of cell-cell junctions. Keratinocytes were examined by double immunofluorescence with antibodies to the desmosome protein, desmoplakin, and the adherens junction protein, vinculin, at intervals after the increase in [Ca2+]. Characteristic Hailey-Hailey disease histopathology was observed by electron microscopy of the patient's skin after trauma, but we found no splitting of desmosomes. Based on the location, intensity, and rate of change of immunofluorescent staining, Hailey-Hailey and normal keratinocytes did not differ in their ability to assemble desmosomes and adherens junctions. Furthermore, we observed no significant morphologic differences between normal and Hailey-Hailey keratinocytes cultured in low and high [Ca2+]-containing media; Hailey-Hailey cells contained abundant normal-appearing desmosomes in 1.1 mM [Ca2+]. Since Hailey-Hailey disease keratinocytes can assemble normal-appearing adherens junctions and desmosomes in vitro, the functional defect may not lie in assembly of cell-cell adhering junctions, or additional perturbation may be required to expose the defect.
Xeroderma Pigmentosum Group C Splice Mutation Associated with Autism and Hypoglycinemia
Creators: name: Kraemer, Kenneth H.
name: Emmert, Steffen
name: Legerski, Randy
name: Li, Lei
name: Cleaver, James E.
name: Schneider, Thomas D.
name: Reardon, Joyce T.
name: Quackenbush, Elizabeth
name: Levy, Harvey L.
name: Khan, Sikandar G.
name: Sancar, Aziz
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: A 4 y old boy of Korean ancestry had xeroderma pigmentosum (XP) with sun sensitivity, multiple cutaneous neoplasms, and inability to speak. Neurologic examination revealed hyperactivity and autistic features without typical XP neurologic abnormalities. Cultured skin fibroblasts (XP22BE) showed decreased post-UV survival, reduced post-UV plasmid host cell reactivation and defective DNA repair (16% of normal unscheduled DNA synthesis in intact cells and undetectable excision repair in a cell free extract). In vitro and in vivo complementation assigned XP22BE to XP group C (XPC) and a markedly reduced level of XPC mRNA was found. Two XPC cDNA bands were identified. One band had a deletion of 161 bases comprising the entire exon 9, which resulted in premature termination of the mutant XPC mRNA. The larger band also had the same deletion of exon 9 but, in addition, had an insertion of 155 bases in its place (exon 9a), resulting in an in-frame XPC mRNA. Genomic DNA analysis revealed a T-->G mutation at the splice donor site of XPC exon 9, which markedly reduced its information content. The 155 base pair XPC exon 9a insertion was located in intron 9 and was flanked by strong splice donor and acceptor sequences. Analysis of the patient's blood showed persistently low levels of glycine (68 microM; NL, 125-318 microM). Normal glycine levels were maintained with oral glycine supplements and his hyperactivity diminished. These data provide evidence of an association of an XPC splice site mutation with autistic neurologic features and hypoglycinemia.
Field theory of absorbing phase transitions with a non-diffusive conserved field
Creators: name: Pastor-Satorras, Romualdo
name: Vespignani, Alessandro
Publisher: name: arXiv
Year: 2000
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We investigate the critical behavior of a reaction-diffusion system exhibiting a continuous absorbing-state phase transition. The reaction-diffusion system strictly conserves the total density of particles, represented as a non-diffusive conserved field, and allows an infinite number of absorbing configurations. Numerical results show that it belongs to a wide universality class that also includes stochastic sandpile models. We derive microscopically the field theory representing this universality class.
description: 13 pages, 1 eps figure, RevTex style
Topological doping and the stability of stripe phases
Creators: name: Pryadko, Leonid P.
name: Kivelson, Steven A.
name: Emery, V. J.
name: Bazaliy, Yaroslaw B.
name: Demler, Eugene A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We analyze the properties of a general Ginzburg-Landau free energy with competing order parameters, long-range interactions, and global constraints (e.g., a fixed value of a total ``charge'') to address the physics of stripe phases in underdoped high-Tc and related materials. For a local free energy limited to quadratic terms of the gradient expansion, only uniform or phase-separated configurations are thermodynamically stable. ``Stripe'' or other non-uniform phases can be stabilized by long-range forces, but can only have non-topological (in-phase) domain walls where the components of the antiferromagnetic order parameter never change sign, and the periods of charge and spin density waves coincide. The antiphase domain walls observed experimentally require physics on an intermediate lengthscale, and they are absent from a model that involves only long-distance physics. Dense stripe phases can be stable even in the absence of long-range forces, but domain walls always attract at large distances, i.e., there is a ubiquitous tendency to phase separation at small doping. The implications for the phase diagram of underdoped cuprates are discussed.
description: 18 two-column pages, 2 figures, revtex+epsf
Osmosis, from molecular insights to large-scale applications
Creators: name: Marbach, Sophie
name: Bocquet, Lyderic
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Applied Physics (physics.app-ph)
subject: Chemical Physics (physics.chem-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Osmosis is a universal phenomenon occurring in a broad variety of processes and fields. It is the archetype of entropic forces, both trivial in its fundamental expression - the van 't Hoff perfect gas law - and highly subtle in its physical roots. While osmosis is intimately linked with transport across membranes, it also manifests itself as an interfacial transport phenomenon: the so-called diffusio-osmosis and -phoresis, whose consequences are presently actively explored for example for the manipulation of colloidal suspensions or the development of active colloidal swimmers. Here we give a global and unifying view of the phenomenon of osmosis and its consequences with a multi-disciplinary perspective. Pushing the fundamental understanding of osmosis allows to propose new perspectives for different fields and we highlight a number of examples along these lines, for example introducing the concepts of osmotic diodes, active separation and far from equilibrium osmosis, raising in turn fundamental questions in the thermodynamics of separation. The applications of osmosis are also obviously considerable and span very diverse fields. Here we discuss a selection of phenomena and applications where osmosis shows great promises: osmotic phenomena in membrane science (with recent developments in separation, desalination, reverse osmosis for water purification thanks in particular to the emergence of new nanomaterials); applications in biology and health (in particular discussing the kidney filtration process); osmosis and energy harvesting (in particular, osmotic power and blue energy as well as capacitive mixing); applications in detergency and cleaning, as well as for oil recovery in porous media.
description: review on osmotic phenomena, accepted for publication to Chemical Society Reviews (final version)
T Cell Receptor β Chain Gene Usage in Endemic Pemphigus Foliaceus (Fogo Selvagem)
Creators: name: Sinha, Animesh A.
name: Lin, Mong-Shang
name: Diaz, Luis A.
name: Moesta, Achim K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: The trimolecular complex comprised of the major histocompatibility complex, peptide antigen, and the T cell receptor is a requisite for T cell activation in normal and autoimmune responses. T cell receptor analysis is critical to further our understanding regarding mechanisms of T cell epitope selection and autoimmune initiation and progression and may help to identify targets for immunotherapy. Pemphigus foliaceus is an autoimmune blistering skin disease characterized by intraepidermal blisters and circulating autoantibodies directed against desmoglein 1, a 160 kDa transmembrane desmosomal molecule expressed in keratinocytes. As tissue damage is mediated by anti-desmoglein 1 antibodies, an initial T cell response is a likely requirement for autoantibody generation in this disease. To elucidate the role of pathogenic T cells in autoimmunity further, we have directly characterized the T cell receptor of T cells derived from pemphigus foliaceus patients. Complementary DNA was isolated from 17 desmoglein 1 specific T cell clones generated from pemphigus foliaceus patients by clonal expansion in vitro. To analyze the T cell repertoire, a panel of primers, collectively specific for the known human T cell receptor beta variable region (TCRBV) families were paired with a constant region primer to polymerase chain reaction to amplify one distinct T cell receptor beta variable region allele for each T cell clone studied. Polymerase chain reaction products were sequenced to determine exact beta chain gene usage. In the 17 clones tested, 10 distinct T cell receptor beta variable region usages and nine T cell receptor beta joining gene segment usages were identified. Furthermore, T cell receptor beta variable region and beta joining usage did not appear to be random, but oligoclonal in nature, with some preference shown for T cell receptor beta variable region 5S1 and T cell receptor BJ2S5.
Magnetic field independence of the spin gap in YBa_2Cu_3O_{7-delta}
Creators: name: Gorny, K.
name: Vyaselev, O. M.
name: Martindale, J. A.
name: Nandor, V. A.
name: Pennington, C. H.
name: Hammel, P. C.
name: Hults, W. L.
name: Smith, J. L.
name: Kuhns, P. L.
name: Reyes, A. P.
name: Moulton, W. G.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report, for magnetic fields of 0, 8.8, and 14.8 Tesla, measurements of the temperature dependent ^{63}Cu NMR spin lattice relaxation rate for near optimally doped YBa_2Cu_3O_{7-delta}, near and above T_c. In sharp contrast with previous work we find no magnetic field dependence. We discuss experimental issues arising in measurements of this required precision, and implications of the experiment regarding issues including the spin or pseudo gap.
description: 4 pages, 3 figures, as accepted for publication in Physical Review Letters
Additional file 1 of Effects of early preventive dental visits and its associations with dental caries experience: a cross-sectional study
Creators: name: Qu, Xing
name: Houser, Shannon H.
name: Tian, Meirong
name: Zhang, Qiong
name: Pan, Jay
name: Zhang, Wei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. S1. ZIBN regression results of association between tooth decay and preventive dental visits among children. S2. Multivariable regression results of association between untreated dental caries and preventive dental visits among children who had dental caries.
The Information Flow Foundation for Conceptual Knowledge Organization
Creators: name: Kent, Robert E.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: The sharing of ontologies between diverse communities of discourse allows them to compare their own information structures with that of other communities that share a common terminology and semantics - ontology sharing facilitates interoperability between online knowledge organizations. This paper demonstrates how ontology sharing is formalizable within the conceptual knowledge model of Information Flow (IF). Information Flow indirectly represents sharing through a specifiable, ontology extension hierarchy augmented with synonymic type equivalencing - two ontologies share terminology and meaning through a common generic ontology that each extends. Using the paradigm of participant community ontologies formalized as IF logics, a common shared extensible ontology formalized as an IF theory, participant community specification links from the common ontology to the participating community ontology formalizable as IF theory interpretations, this paper argues that ontology sharing is concentrated in a virtual ontology of community connections, and demonstrates how this virtual ontology is computable as the fusion of the participant ontologies - the quotient of the sum of the participant ontologies modulo the ontological sharing structure.
description: 7 pages, 3 figures, 1 table
Cyclotron Resonance in the Layered Perovskite Superconductor Sr2RuO4
Creators: name: Hill, S.
name: Brooks, J. S.
name: Mao, Z. Q.
name: Maeno, Y.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have measured the cyclotron masses in Sr2RuO4 through the observation of periodic-orbit-resonances - a magnetic resonance technique closely related to cyclotron resonance. We obtain values for the alpha, beta and gamma Fermi surfaces of (4.33+/-0.05)me, (5.81+/-0.03)me and (9.71+/-0.11)me respectively. The appreciable differences between these results and those obtained from de Haas- van Alphen measurements are attributable to strong electron-electron interactions in this system. Our findings appear to be consistent with predictions for a strongly interacting Fermi liquid; indeed, semi-quantitative agreement is obtained for the electron pockets beta and gamma.
description: 4 pages + 3 figures