cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Human CST abundance determines recovery from diverse forms of DNA damage and replication stress
Creators: name: Wang, Feng
name: Stewart, Jason
name: M Price, Carolyn
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Medicine
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: Mammalian CST (CTC1-STN1-TEN1) is a telomere-associated complex that functions in telomere duplex replication and fill-in synthesis of the telomeric C-strand following telomerase action. CST also facilitates genome-wide replication recovery after HU-induced fork stalling by increasing origin firing. CTC1 and STN1 were originally isolated as a DNA polymerase α stimulatory factor. Here we explore how CST abundance affects recovery from drugs that cause different types of DNA damage and replication stress. We show that recovery from HU and aphidicolin induced replication stress is increased by CST over-expression. Elevated CST increases dNTP incorporation and origin firing after HU release and decreases the incidence of anaphase bridges and micronuclei after aphidicolin removal. While the frequency of origin firing after HU release is proportional to CST abundance, the number of cells entering S-phase to initiate replication is unchanged by CST overexpression or STN1 depletion. Instead the CST-related changes in origin firing take place in cells that were already in S-phase at the time of HU addition, indicating that CST modulates firing of late or dormant origins. CST abundance also influences cell viability after treatment with HU, aphidicolin, MMS and camptothecin. Viability is increased by elevated CST and decreased by STN1 depletion, indicating that endogenous CST levels are limiting. However, CST abundance does not affect viability after MMC treatment. Thus, CST facilitates recovery from many, but not all, forms of exogenous DNA damage. Overall our results suggest that CST is needed in stoichiometric amounts to facilitate re-initiation of DNA replication at repaired forks and/or dormant origins.
Do ter e da alienação
Creators: name: Moura, José Barata
Publisher: name: Didaskalia
Year: 1973

description: Le présent article, dont le titre est: «De l'avoir et de l'aliénation», se propose d'attirer l'attention sur quelques uns des principaux traits qui peuvent caractériser les rapports entre ces deux notions. Après un bref examen de la possibilité d'un usage idéologique de la distinction établie entre «être» et «avoir», l'auteur considère cette dichotomie dans le cadre du problème éthique et ontologique de l'orientation de l'homme dans le monde. «Etre» et «avoir» correspondent à deux catégories bien différentes d'envisager le fondement à partir duquel se détermine la conduite humaine. Celui qui se définit par l'«avoir» se détermine à partir d'un autre qui, à vrai dire, est lui aussi quelque chose d'étranger. Le pouvoir fondé sur cet «avoir» se présente, en quelque sorte, comme une illusion, dans la mesure où, en effet, celui qui le détient exerce sa «domination» au prix d'une dépendance réelle vis-à-vis de ce qu'il possède. Le «possesseur», dès qu'un regard immédiat est surmonté, apparaît, en réalité, comme «possédé». L'aliénation s'étend, par conséquent, aux deux membres de la relation définie par l'«avoir». Une allusion sommaire est égalemente faite à cette conception de la réversibilité de la relation d'aliénation que l'on peut retrouver déjà chez HEGEL, notamment dans ses références à la dialectique du «seigneur» et de l'«esclave», et chez le jeune MARX. L'«avoir» en tant que catégorie ayant une signification dans le domaine éthico-ontologique se présente donc comme une modalité fondamentale de l'aliénation. Celui qui se définit par 1'«avoir» n'est que par reflet et dépendance: il ne possède pas vraiment un être propre.
description: Didaskalia, v. 3 n. 2 (1973)
title: KLIMONAS-Ch24-A01 - Liste et mesures des dactylopidites et propodites de crabes d'eau douce (Potamon sp.) trouvés à Klimonas
title: KLIMONAS-Ch24-A01 - List and measurements of the dactylopidites and propodites of freshwater crabs (Potamon sp.) found at Klimonas
Creators: name: VIGNE, Jean-Denis
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: Appendix of: Vigne J.-D., Briois F., Guilaine J. (eds.), « Klimonas, an Early Pre-Pottery Neolithic village in Cyprus », Gallia Préhistoire & Paléorient, International Supplement 1, CNRS Éditions, Paris, 2023.
description: Annexe de : Vigne J.-D., Briois F., Guilaine J. (dir.), « Klimonas, un village néolithique pré-céramique ancien à Chypre », Gallia Préhistoire & Paléorient, Supplément international 1,CNRS Éditions, Paris, 2023.
Human CST abundance determines recovery from diverse forms of DNA damage and replication stress
Creators: name: Wang, Feng
name: Stewart, Jason
name: M Price, Carolyn
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Medicine
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: Mammalian CST (CTC1-STN1-TEN1) is a telomere-associated complex that functions in telomere duplex replication and fill-in synthesis of the telomeric C-strand following telomerase action. CST also facilitates genome-wide replication recovery after HU-induced fork stalling by increasing origin firing. CTC1 and STN1 were originally isolated as a DNA polymerase α stimulatory factor. Here we explore how CST abundance affects recovery from drugs that cause different types of DNA damage and replication stress. We show that recovery from HU and aphidicolin induced replication stress is increased by CST over-expression. Elevated CST increases dNTP incorporation and origin firing after HU release and decreases the incidence of anaphase bridges and micronuclei after aphidicolin removal. While the frequency of origin firing after HU release is proportional to CST abundance, the number of cells entering S-phase to initiate replication is unchanged by CST overexpression or STN1 depletion. Instead the CST-related changes in origin firing take place in cells that were already in S-phase at the time of HU addition, indicating that CST modulates firing of late or dormant origins. CST abundance also influences cell viability after treatment with HU, aphidicolin, MMS and camptothecin. Viability is increased by elevated CST and decreased by STN1 depletion, indicating that endogenous CST levels are limiting. However, CST abundance does not affect viability after MMC treatment. Thus, CST facilitates recovery from many, but not all, forms of exogenous DNA damage. Overall our results suggest that CST is needed in stoichiometric amounts to facilitate re-initiation of DNA replication at repaired forks and/or dormant origins.
Intrinsic and Extrinsic Nature of Time and Space in Contemporary Installation
Creators: name: Baker, Victoria
Publisher: name: Monash University
Year: 2017
Subjects: Art

description: The role of time and space in contemporary art is not a simplistic linear relationship. Instead it is a complex network, where every aspect of time within an artwork is reliant on the surrounding space, or vice versa. In fact I believe that the relationship between time, space and contemporary art is as complex and diverse as the terms time and space themselves. This article presents an overview of my current research, and introduces the integral terminology and methodology. Therefore, some concepts are not dealt with as extensively as I might otherwise wish and I am only able to summarise this relationship between time, space and contemporary art. Initially, in order to understand the complexity of this network, a causal model representing the full life-space of an artwork will be briefly introduced. The key to deconstructing these complex relationships is to identify the suitable terminology, therefore I will utilize the dual concepts of intrinsic and extrinsic to identify time and space, and to enable a deconstruction of contemporary art work. Examples of installations featured in the 2004 Biennale of Sydney will be used and due to word constraints this article will briefly consider the generic concept of contemporary installation. The methodology presented can be effectively applied to the deconstruction of any contemporary medium.
Vestígios de milenarismo em Alcobaça?
Creators: name: Bragança, Joaquim De Oliveira
Publisher: name: Didaskalia
Year: 1971

description: O Códice Alcobacense 164 da Biblioteca Nacional de Lisboa consta na realidade de dois documentos, escritos por mão diferente, com numeração independente. O primeiro, de 25 fólios, é um Antifonário da Missa, contendo as principais festas do ano, dos fins do séc. XIII. O segundo, com 7 fólios apenas, contém um Hinário e Antifonário do Ofício para a Hora de Tércia, uma ladainha (fól. 5 v.), algumas orações de preparação para a comunhão, formulários de aspersão da água lustral aos domingos, uma colecta sálmica (fól. 7 v.: Hec oratio debet dici post septem psalmos) e uma fórmula de absolvição sacramental (Talis absolutio debet fieri a confessore, super sibi confitentem), com que termina. Este manuscrito é já do séc. XIV.
description: Didaskalia, v. 1 n. 1 (1971)
PRATIQUES DE CONSOMMATION ET PROCESSUS DE CHANGEMENT ORGANISATIONNEL : CAS DU MARCHE DE L'INFORMATION EN LIGNE
Creators: name: BENABID, Mohamed
Publisher: name: Paris VIII University
Year: 2018

description: The literature on change does not adequately capture the influence of micro-organizational determinants such as consumption practices. By mobilizing two theoretical frameworks, the neo-institutional theory (NIT) and technology acceptance model, and relying on the online information market in Morocco, our thesis aims to better take into account this perspective. Our research is comprehensive and explanatory and uses a mixed qualitative-quantitative methodology through a pragmatic epistemological positioning. Our results show that consumer-driven change in online information is not motivated by an institutional agenda or, to put it another way, by shifting the course of events. It seems to be only a collateral effect of his activities. Our research also highlights the institutional status of consumer practices, which are driven by regulatory, normative and cognitive institutional pillars. While the cognitive pillar of free information provides organizational opportunities for change in the context of the electronic press, it continues to challenge the issue of monetization. The results of our quantitative analysis also suggest the existence of significant relationships between the intention to purchase online news and cognitive constructs: the free mentality, perceived fairness, perceived credibility. We show that monetization is a question of both technical and psychosocial factors that continue to be a barrier to the challenges of the economic model.
Additional file 1 of Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology
Creators: name: Blohmer, Martin
name: Zhu, Li
name: Atkinson, Jennifer M.
name: Beriwal, Sushil
name: Rodríguez-López, Joshua L.
name: Rosenzweig, Margaret
name: Brufsky, Adam M.
name: Tseng, George
name: Lucas, Peter C.
name: Lee, Adrian V.
name: Oesterreich, Steffi
name: Jankowitz, Rachel C.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1. Comparison of time from diagnosis of the primary tumor to a site-specific first metastases. Displayed is a comparison of the time to first ophthalmic metastasis with the time to first metastasis at a specific anatomical site. Data on the time to first metastasis at a specific anatomical site was abstracted from the Metastatic Breast Cancer Database.
Datasaet for: Acute Effects of Slow-Paced Breathing on Measures of HRV in Hospitalized Patients With Bilateral COVID-19 Pneumonia: A Secondary Analysis of a Randomized Clinical Trial
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2024
Subjects: subject: Slow-paced breathing
subject: COVID-19 pneumonia
subject: Breathing intervention
subject: Heart rate variability
subject: HRV
subject: DDC 610 / Medicine & health
subject: Vagus Nerve Stimulation
subject: COVID-19
subject: Clinical Trial
subject: Klinische Prüfung
subject: Herzfrequenzvariabilität

description: This study evaluated the feasibility and effectiveness of slow-paced breathing (SPB) with prolonged exhalation in hospitalized COVID-19 pneumonia patients. Conducted as a randomized controlled trial, it demonstrated that SPB significantly increased heart rate variability (HRV) measures during SPB even in severely ill patients with reduced baseline HRV. SPB was found to be a safe, self-performed intervention that may help boost autonomic function in critically ill patients, suggesting its potential therapeutic value beyond COVID-19.
Writing the Subject: Virginia Woolf and Clothes
Creators: name: Abbs, Carolyn
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200503 British and Irish Literature
subject: FOS: Languages and literature

description: Virginia Woolf had a fascination with clothes and textiles. She wrote about clothes in her diaries, fiction and non-fiction and she even wrote for Vogue magazine – the editor was a friend. There may have been some influence from William Morris’s designs and tapestries, the Omega workshops of the time, Serge Diaghilev and costume designs for the Ballets Russes, and we know that she worked needlepoint with her sister Vanessa Bell. However, in regard to writing the subject, it was more than a mere fascination with clothes: she recognized the important link between clothes and the body. The other aspect of her life and work of relevance here is her intrigue with childhood and childhood experience – particularly the memory of her mother. I am interested in the way Woolf’s fascination with clothes and intrigue are entwined with childhood experience and memory in her work. In this paper, I suggest that Virginia Woolf has a method of writing the subject that involves clothes and textiles. The method stems from her autobiographical writing, in particular the childhood memory of her mother, and is carried through into her novelistic practice. I will argue that Woolf is able to fictionalize/re-work memory as perception of the body by involving “clothes and textiles”; that is, she understands a confluence between body and clothes which she writes via the nonverbal and, in particular, the tactile to create the subject in her writing practice. It is this confluence which I understand as “writing the subject.”
Formy skrócone
Creators: name: Olszewski, Krzysztof
Publisher: name: figshare
Year: 2017
Subjects: subject: 200312 Japanese Language
subject: FOS: Languages and literature

description: Przegląd form skróconych w języku japońskim zachodzących w koniugacji czasownika, a typowych dla kolokwialnej japońszczyzny.
L'Esprit Saint dans l'euchologie médiévale
Creators: name: Bragança, Joaquim De Oliveira
Publisher: name: Didaskalia
Year: 1973

description: Le Moyen-Age veut sanctifier toute action, qu'elle soit liturgique ou simplement humaine. Les moindres gestes sont remplis d'une valeur symbolique et pourvus d'une prière. C'est ainsi que naît, par exemple, l'Ordo missae. Dans le vaste domaine des bénédictions signalons uniquement les plus importantes, celles qui jallonnent le rythme de l'année liturgique: la bénédiction des cendres, la bénédiction des cierges le 2 Février et celle des rameaux. Il est évident que nous ne pouvons pas faire, dans ces quelques minutes dont nous disposons, une analyse de l'ensemble de l'euchologie médiévale. Aussi nous avons choisi trois points, parmi les plus saisissants, pour notre travail: les prières de la messe, les messes votives carolingiennes et la bénédiction de la lumière.
description: Didaskalia, v. 3 n. 2 (1973)
Brain Function, Learning, and Role of Feedback in Complete Paralysis
Creators: name: Silvoni, Stefano
name: Occhigrossi, Chiara
name: Di Giorgi, Marco
name: Lulé, Dorothée
name: Birbaumer, Niels
Publisher: name: Universität Ulm
Year: 2024
Subjects: subject: Completely locked-in state
subject: Operant learning
subject: Neurofeedback
subject: Reinforcement
subject: Goal-directed thinking
subject: Cognition
subject: Psychosocial context
subject: Communicative barrier
subject: DDC 610 / Medicine & health

description: The determinants and driving forces of communication abilities in the locked-in state are poorly understood so far. Results from an experimental–clinical study on a completely paralyzed person involved in communication sessions after the implantation of a microelectrode array were retrospectively analyzed. The aim was to focus on the prerequisites and determinants for learning to control a brain–computer interface for communication in paralysis. A comparative examination of the communication results with the current literature was carried out in light of an ideomotor theory of thinking. We speculate that novel skill learning took place and that several aspects of the wording of sentences during the communication sessions reflect preserved cognitive and conscious processing. We also present some speculations on the operant learning procedure used for communication, which argues for the reformulation of the previously postulated hypothesis of the extinction of response planning and goal-directed ideas in the completely locked-in state. We highlight the importance of feedback and reinforcement in the thought–action–consequence associative chain necessary to maintain purposeful communication. Finally, we underline the necessity to consider the psychosocial context of patients and the duration of complete immobilization as determinants of the ‘extinction of thinking’ theory and to identify the actual barriers preventing communication in these patients. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury
Creators: name: Huang, Jin
name: Wan, Danyang
name: Li, Jianshuang
name: Chen, Hong
name: Huang, Kun
name: Zheng, Ling
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Marine Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: Kidney diseases, including chronic kidney disease (CKD) and acute kidney injury (AKI), are associated with inflammation. The mechanism that regulates inflammation in these renal injuries remains unclear. Here, we demonstrated that p300/CBP-associated factor (PCAF), a histone acetyltransferase, was overexpressed in the kidneys of db/db mice and lipopolysaccharide (LPS)-injected mice. Moreover, elevated histone acetylation, such as H3K18ac, and up-regulation of some inflammatory genes, such as ICAM-1, VCAM-1, and MCP-1, were found upon these renal injuries. Furthermore, increased H3K18ac was recruited to the promoters of ICAM-1, VCAM-1, and MCP-1 in the kidneys of LPS-injected mice. In vitro studies demonstrated that PCAF knockdown in human renal proximal tubule epithelial cells (HK-2) led to downregulation of inflammatory molecules, including VCAM-1, ICAM-1, p50 subunit of NF-κB (p50), and MCP-1 mRNA and protein levels, together with significantly decreased H3K18ac level. Consistent with these, overexpression of PCAF enhanced the expression of inflammatory molecules. Furthermore, PCAF deficiency reduced palmitate-induced recruitment of H3K18ac on the promoters of ICAM-1 and MCP-1, as well as inhibited palmitate-induced upregulation of these inflammatory molecules. In summary, the present work demonstrates that PCAF plays an essential role in the regulation of inflammatory molecules through H3K18ac, which provides a potential therapeutic target for inflammation-related renal diseases.
VII Congresso Mariológico Internacional
Creators: name: Bragança, Joaquim De Oliveira
Publisher: name: Didaskalia
Year: 1975

description: Celebrou-se em Roma, de 12 a 17 de Maio último, o VII Congresso Mariológico Internacional, congresso que se realiza de quatro em quatro anos por iniciativa da «Pontifícia Academia Mariana Internationalis», de que é Presidente o P. Carolus Balic, O. F. M., figura internacionalmente conhecida, coadjuvado pelo P. Paulo Melada, O. F. M., Secretário da Academia. A escolha de Roma para o congresso deste ano deve-se à vontade expressa de Paulo VI, por coincidir com o Ano Santo de 1975.
description: Didaskalia, v. 5 n. 1 (1975)
Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury
Creators: name: Huang, Jin
name: Wan, Danyang
name: Li, Jianshuang
name: Chen, Hong
name: Huang, Kun
name: Zheng, Ling
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Marine Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: ABSTRACTKidney diseases, including chronic kidney disease (CKD) and acute kidney injury (AKI), are associated with inflammation. The mechanism that regulates inflammation in these renal injuries remains unclear. Here, we demonstrated that p300/CBP-associated factor (PCAF), a histone acetyltransferase, was overexpressed in the kidneys of db/db mice and lipopolysaccharide (LPS)-injected mice. Moreover, elevated histone acetylation, such as H3K18ac, and up-regulation of some inflammatory genes, such as ICAM-1, VCAM-1, and MCP-1, were found upon these renal injuries. Furthermore, increased H3K18ac was recruited to the promoters of ICAM-1, VCAM-1, and MCP-1 in the kidneys of LPS-injected mice. In vitro studies demonstrated that PCAF knockdown in human renal proximal tubule epithelial cells (HK-2) led to downregulation of inflammatory molecules, including VCAM-1, ICAM-1, p50 subunit of NF-κB (p50), and MCP-1 mRNA and protein levels, together with significantly decreased H3K18ac level. Consistent with these, overexpression of PCAF enhanced the expression of inflammatory molecules. Furthermore, PCAF deficiency reduced palmitate-induced recruitment of H3K18ac on the promoters of ICAM-1 and MCP-1, as well as inhibited palmitate-induced up-regulation of these inflammatory molecules. In summary, the present work demonstrates that PCAF plays an essential role in the regulation of inflammatory molecules through H3K18ac, which provides a potential therapeutic target for inflammation-related renal diseases.
Étude expérimentale de la formulation des mortiers à base de sable recyclé
Creators: name: Berredjem, Layachi
name: Molez, Laurent
name: Nguyen, Van-Minh
name: Mefteh, Houria
name: Arabi, Nourredine
Publisher: name: Academic Journal of Civil Engineering
Year: 2020

description: Ce travail est une contribution expérimentale à l'étude de l’incorporation du sable recyclé dans les mortiers de ciment et leurs influences sur les comportements rhéologiques et mécaniques de ces mortiers avec et sans adjuvants. A la suite de l’identification et la caractérisation des sables en particulier les recyclés, le comportement rhéologique s’est porté sur différents mélanges de mortiers à base du ciment CEM I 52,5 et avec E/C=0,5, en substituant le sable naturel par le sable recyclé avec différents pourcentages volumiques de : 0, 15, 30, 40, 50, 75 et 100 %. Les résultats obtenus montrent que le sable recyclé a une absorption d’eau très importante, sept fois plus élevée que celle du sable naturel alluvionnaire, un pourcentage élevé des fillers de 5% en moyenne. Les propriétés physico-chimiques assez faibles par rapport au sable naturel, dues à l’hétérogénéité et le grand pourcentage d’ancien mortier que contient le sable recyclé. Cependant, l’étude comparative entre les différentes compositions de mortiers de sable recyclé a montré des comportements physiques et rhéologiques comparables et des performances mécaniques meilleures à ceux du mortier témoin à base de sable naturel pour toutes les échéances.
description: Academic Journal of Civil Engineering, Vol 34 No 1 (2016): Special Issue - RUGC 2016 Liège
The Woman-Object’s Glorious New Clothes – Liz Conor. The Spectacular Modern Woman: Feminine Visibility in the 1920s. Bloomington: Indiana UP, 2004; Juliette Peers. The Fashion Doll: From Bébé Jumeau to Barbie. Oxford and New York: Berg, 2004 [Review article]
Creators: name: Walton, Robyn
Publisher: name: Monash University
Year: 2017
Subjects: Gender studies

description: “Dolls raise so many issues about the representation and cultural positioning of the feminine in society,” writes Juliette Peers in the “Introduction” to her book The Fashion Doll (Peers: 8). Liz Conor might well have begun her text about feminine visibility by using the same statement, substituting for “dolls” the words “mass media images of women.” “Appearance” and “appearing,” in their multiple meanings, are also key words for both authors. Peers’s primary interest is fashionably dressed dolls’ appearance (looks) and appearance (emergence) in the market-place, while Conor elaborates on the emergence of the “new formation of subjectivity” she calls the Modern Appearing Woman in the technologically enhanced ocular field of the 1920s.
L'Esprit-Saint et l'Eglise dans la «Tradition apostolique» de Saint Hippolyte
Creators: name: Botte, Bernard
Publisher: name: Didaskalia
Year: 1972

description: La Tradition apostolique est un document qu'il est difficile de classer d'après nos genres littéraires. Elle a un aspect canonique par le fait qu'elle donne des règles précises et très concrètes pour la vie d'une communauté chrétienne. D'autre part, elle contient une série de prières liturgiques qui expriment la foi de l'Eglise, et elle a par là un caractère théologique, notamment au sujet de l'Esprit-Saint.
description: Didaskalia, v. 2 n. 2 (1972)
مفهوم الانفتاح
Creators: name: Baleela, Rania
Publisher: name: Rania Baleela
Year: 2024
Subjects: Open access
Open Science
Openness

description: A Key presentation presented at the Open Science workshop organized by the The Sudanese National Commission for Education, Science and Culture during teh period from December 21-22, 2021

مفهوم االانفتاحورقة مقدمة لحلقة عمل المصادر التعليمية المفتوحة - اللجنة الوطنية السودانية للتربية والعلم والثقافةد. رانيه محمد حسن بليله، جامعة الخرطوممنسق الوصول الحر EIFL
Astrid Henry. Not My Mother’s Sister: Generational Conflict and Third Wave Feminism. Bloomington: U of Indiana P, 2004 [Book review]
Creators: name: Taylor, Anthea
Publisher: name: Monash University
Year: 2017
Subjects: Gender studies

description: In Not My Mother’s Sister, Astrid Henry critiques the excessive use of generational tropes and familial metaphors in American “third-wave” texts. Henry’s stated aim is to analyse how the mother-daughter trope has become the central means of figuring relationships between second-wave and third-wave feminists in the US (2). In so doing, Not My Mother’s Sister fills a significant critical gap within feminist textual studies, specifically in relation to the rhetoric of ‘popular’ feminist writing. Her study consists of close analyses of a number of US texts defined as products of third-wave feminism and which exemplify the “overmaternalization of feminism” (146). She trenchantly observes that such works repeatedly view feminism as a symbolic Mother necessitating repudiation to permit the individuation of her wayward daughter. The feminist publications she analyses, both ‘popular’ and academic (although most can be categorised as the former), are clustered in the 1990s, the point at which she argues the third-wave becomes most culturally visible. An Australian audience may be tempted to read the highly visible media debates over the meaning (and ‘ownership’) of feminism in the 1990s, precipitated by the publication of Helen Garner’s The First Stone, through Henry’s observations on the third-wave. However, the term’s application and currency in Australia has been comparatively limited, either in ‘mainstream’ or academic contexts. Nonetheless, her unpacking of generational tropes and maternal metaphors provides important insight into how relationships between different cohorts of feminists are being figured.
مفهوم الانفتاح
Creators: name: Baleela, Rania
Publisher: name: Zenodo
Year: 2024

description: A Key presentation presented at the Open Science workshop organized by the The Sudanese National Commission for Education, Science and Culture during teh period from December 21-22, 2021

مفهوم االانفتاحورقة مقدمة لحلقة عمل المصادر التعليمية المفتوحة - اللجنة الوطنية السودانية للتربية والعلم والثقافةد. رانيه محمد حسن بليله، جامعة الخرطوممنسق الوصول الحر EIFL
Elizabeth Grosz. The Nick of Time: Politics, Evolution and the Untimely. Sydney: Allen and Unwin, 2004; Elizabeth Grosz. Time Travels: Feminism, Nature, Power. Sydney: Allen and Unwin, 2005 [Book review]
Creators: name: Perkins, Claire
Publisher: name: Monash University
Year: 2017
Subjects: subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: With her two books, The Nick of Time and Time Travels, Elizabeth Grosz joins those writers and thinkers for whom the phenomenon of temporality holds a particular fascination. Grosz acknowledges early on in The Nick of Time that there are many Western philosophical traditions that could hold direct relevance for her attempt to reconsider the relationship between time and life, but which are nonetheless neglected. She identifies, in particular, the pragmatic and phenomenological traditions, which are both passed over in favour of the first book's exclusive focus on Charles Darwin, Friedrich Nietzsche and Henri Bergson, and the second's wider, but still eclectic, additions to this trio: Gilles Deleuze, Jacques Derrida, Michel Foucault, Alfred Kinsey, William James, Luce Irigaray and Maurice Merleau-Ponty.
title: 01_0978
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Reflexos da vida marítima num autor espiritual do século XVI
Creators: name: Marques, Armando De Jesus
Publisher: name: Didaskalia
Year: 1975

description: Sebastião Toscano — um irmão de hábito e coetâneo de Frei Tomé de Jesus — passou quase inadvertido até ao presente, embora seja um bom escritor e uma personalidade de certo relevo na história religiosa da sua época. Nasceu no Porto em 1515. Secretário do famoso geral Seripando, pregador de D. João III, incumbido de uma espinhosa missão diplomática aquando do cisma inglês, chegou, por duas vezes, a provincial dos Eremitas de Santo Agostinho — a Ordem em que professara, ainda moço, quando estudava Leis na Universidade de Salamanca.
description: Didaskalia, v. 5 n. 1 (1975)
title: How the number of fitting points for the slope of the mean-square displacement influences the experimentally determined particle size distribution from single-particle tracking
Creators: name: Ernst, Dominique
name: Köhler, Jürgen
Publisher: name: University of Bayreuth
Year: 2013
Subjects: subject: 530

description: The size distribution of nanoparticles can be determined by single-particle tracking. This yields the mean-squared displacement (MSD) as a function of the lag time, and for normal diffusion the slope of this curve is directly related to the diffusion coefficient or via the Stokes-Einstein relation to the particle size. Here we demonstrate how the experimentally determined size distributions are affected by the number of fitting points used to determine the slope of the MSD curve.
Additional file 1 of Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat
Creators: name: Saleh, Dina Mourad
name: Alexander, William T.
name: Numano, Takamasa
name: Ahmed, Omnia Hosny Mohamed
name: Gunasekaran, Sivagami
name: Alexander, David B.
name: Abdelgied, Mohamed
name: El-Gazzar, Ahmed M.
name: Takase, Hiroshi
name: Xu, Jiegou
name: Naiki-Ito, Aya
name: Takahashi, Satoru
name: Hirose, Akihiko
name: Ohnishi, Makoto
name: Kanno, Jun
name: Tsuda, Hiroyuki
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Pharmacology
Biological Sciences not elsewhere classified
Cancer

description: Additional file 1: Additional Figure 1. (A) Length distribution of airborne MWCNT-A prior to homogenization in vehicle and after homogenization in vehicle. (B) Length distribution of airborne MWCNT-B prior to homogenization in vehicle and after homogenization in vehicle.
«O homem moderno quer uma moral moderna»
Creators: name: Silva, António Pereira Da
Publisher: name: Didaskalia
Year: 1971

description: Discurso denso e sugestivo consagrou Paulo VI, em data recente, à renovação da Teologia Moral. É dele a asserção que serve de título a este breve comentário e que, não obstante a sua ambiguidade, sintetiza uma aspiração nobre, uma exigência iniludível do homem contemporâneo. Interpretando a vontade do Concílio Vaticano II e na sequência de outros actos de seu magistério, Paulo VI, no presente discurso, acolhe de bom grado tal anseio e necessidade e evoca alguns princípios fundamentais solidariamente implicados no agir humano e cristão e que nunca devem ser descurados numa sábia modernização ou actualização da Teologia Moral. Refere-se designadamente à ordem moral, à lei natural e positiva, e à consciência.
description: Didaskalia, v. 1 n. 1 (1971)
O género literário de «Judite» e os Macabeus
Creators: name: Carreira, José Nunes
Publisher: name: Didaskalia
Year: 1973

description: Some unanimity has been reached among biblical scholars with regards to the original text and the date of the deutero-canonical Book of Judith. But many doubts and uncertainties remain concerning its literary form. It is fairly easy to say what it is not. It is more difficult to know what it really is. A. Lefèvre maintains that there is no proper word to call it. This literary form has no name, says Dubarle. J. Steinmann and A. Barucq tend to the apocalyptical form. E. Haag classifies the book as «parabolische Geschichts-darstellung». This is the best name provided, however, that the book is not considered as pure theological dissertation. The «parable» is based on the vital experience of the Maccabees'wars of liberation. The comparison between Dan and Jdt on one hand and 1 Mac and Jdt on the other hand leads to this conclusion.
description: Didaskalia, v. 3 n. 2 (1973)
Second virial coefficient derivations from Cation effects on haemoglobin aggregation: balance of chemisorption against physisorption of ions
Creators: name: Parsons, Drew F.
name: Duignan, Timothy T.
name: Salis, Andrea
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 30699 Physical Chemistry not elsewhere classified
subject: FOS: Chemical sciences

description: Derivation of relationships between the second virial coefficient and aggregation and turbidity.
A essencialidade judicativa da crítica
Creators: name: Enes, José
Publisher: name: Didaskalia
Year: 1972

description: 1. Conteúdo experiencial de «crítica» 2. A essencialidade da função judicativa 3. Inteligência e razão 4. Juízos da inteligência e juízos da razão 5. Expressão oral dos juízos da inteligência 6. Estrutura noética do raciocínio 7. A atitude noética da Crítica
description: Didaskalia, v. 2 n. 2 (1972)
Effects of epigallocatechin gallate on the cell-wall structure of Mycobacterial smegmatis mc2155
Creators: name: Sun, Tieying
name: Qin, Biaojie
name: Gao, Mingchuan
name: Yin, Yuling
name: Wang, Changyuan
name: Zang, Shizhu
name: Li, Xinli
name: Zhang, Cuili
name: Xin, Yi
name: Jiang, Tao
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Developmental Biology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: Epigallocatechin gallate (EGCG) is the main component of green tea extracts that inhibits the growth of Mycobacterial smegmatis mc2155, and the mechanism is not clear. This study showed the effects of EGCG on the growth of mc2155. The content and the structure of EGCG in LB medium with mc2155 were identified by HPLC and LC/MS. Transmission electron microscopy was utilised to identify the cell envelope structure. As a result, the optional inhibition concentration was determined to be 20 μg mL− 1. Most of EGCG was transferred into its isomeride in LB medium, but the inhibition effects against mc2155 had yet been maintained. The changes of cell envelope structure were showed after EGCG treatment for 18 h. The cell wall appeared to have a less electron-translucent zone, turn rougher and thicker. The results show that EGCG impacts the integrity of mycobacterial cell wall and is likely be a better prophylactic agent against tuberculosis.
D. Pedro de Figueiró e a sua obra exegética
Creators: name: Rodrigues, Manuel Augusto
Publisher: name: Didaskalia
Year: 1975

description: D. Pedro cultivou esmeradamente o estudo das línguas, especialmente das orientais (Hebraico, Aramaico e Árabe), no que havia de se tornar um dos maiores especialistas portugueses de todos os tempos. Era mesmo conhecido pelo epíteto de «o Hebreu» em atenção ao profundo domínio que possuía deste idioma. Consagrando-se com muito afinco e inexcedível devoção à penetração dos mistérios das Ciências Bíblicas, depressa grangeou enorme fama e admiração entre os seus contemporâneos. A óptima preparação linguística que possuía e a vasta erudição alcançada, quer no domínio profano, quer no das ciências sagradas, soube ele colocá-las admiravelmente ao serviço da Exegese escriturística, em que havia de se evidenciar como Mestre consumado.
description: Didaskalia, v. 5 n. 1 (1975)
Insight into the impact of environments on structure of chimera C3 of human β-defensins 2 and 3 from molecular dynamics simulations
Creators: name: Li, Qianqian
name: Yu, Hui
name: Zhao, Xi
name: Huang, Xuri
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Information and Computing Sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Biotechnology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physics
subject: Biochemistry
subject: Biophysics

description: C3 is a chimera from human β-defensins 2 and 3 and possesses higher antimicrobial activity compared with its parental molecules, so it is an attractive candidate for clinical application of antimicrobial peptides. In continuation with the previous studies, molecular dynamics (MD) simulations were carried out for further investigating the effect of ambient environments (temperature and bacterial membrane) on C3 dynamics. Our results reveal that C3 has higher flexibility, larger intensity of motion, and more relevant secondary structural changes at 363 K to adapt the high temperature and maintain its antimicrobial activity, comparison with it at 293 K; when C3 molecule associates with the bacterial membrane, it slightly fluctuates and undergoes local conformational changes; in summary, C3 molecule demonstrates stable conformations under these environments. Furthermore, MD results analysis show that the hydrophobic contacts, the hydrogen bonds, and disulfide bonds in the peptide are responsible for maintaining its stable conformation. In addition, our simulation shows that C3 peptides can make anionic lipids clustered in the bacterial membrane; it means that positive charges and pronounced regional cationic charge density of C3 are most key factors for its antimicrobial activity.
«Ela te esmagará a cabeça» (Gn. 3, 15b)
Creators: name: Castro, Joaquim Mendes De
Publisher: name: Didaskalia
Year: 1971

description: Quando, precisamente há uma década, traduzíamos do original o livro do Génesis para a Bíblia Ilustrada, pudemos sentir a responsabilidade e a angústia de escolher entre lições prováveis a que havia de constar da primeira versão portuguesa da Bíblia hebraica.
description: Didaskalia, v. 1 n. 1 (1971)
O bispo-menino, o rito de Salisbúria e a capela real portuguesa
Creators: name: Martins, Mário
Publisher: name: Didaskalia
Year: 1972

description: O Natal caía a 25 de Dezembro. A 26, era a festa de S. Estêvão. A 27, era a festa de S. João Evangelista. E no dia 28, a festa dos Santos Inocentes, esses meninos anónimos que Herodes mandou matar. Ora, nas catedrais da Idade Média e de acordo com velhos costumes, as crianças, sobretudo os meninos de coro, julgavam seu o dia dos Santos Inocentes, com vésperas solenes no dia anterior. E o mundo pertencia-lhes durante vinte e quatro horas, pelo menos. O mundo, quer dizer, a catedral, o paço do bispo, um pouco as ruas da cidade, etc. Assistia-se, então, à vitória da inocência (esta a ideia primitiva) e da irresponsabilidade lúdica de quem não tinha contas a dar. Com efeito, naquele dia, em muitas sés ficava de lado o prelado diocesano, substituído pelo bispo dos inocentes (episcopus innocentium) ou então bispo dos meninos (episcopus pueroruim). Certo documento de 1419, de além-Pirenéus, refere-se ao «pequeno báculo» e às sandàliazinhas para o minibispo. Um breviário de Salisbúria apontado por Du Cange (fixemo-nos bem neste caso) ordenava que os meninos de coro tivessem bispo seu: Pueri chori suum habeant episcopum.
description: Didaskalia, v. 2 n. 1 (1972)
Geissoschizine methyl ether N-oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla
Creators: name: Jiang, Wei-Wei
name: Su, Jia
name: Wu, Xing-De
name: He, Juan
name: Peng, Li-yan
name: Cheng, Xiao
name: Zhao, Qin-shi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Neuroscience
Biochemistry

description: Geissoschizine methyl ether N-oxide, a new oxindole alkaloid, along with 14 known alkaloids, was isolated from the aerial part of Uncaria rhynchophylla. Their structures were identified by comprehensive spectral methods, including 2D NMR experiments, and confirmed by comparing with the literature data. In vitro acetylcholinesterase (AChE) inhibitory activity assay showed that the new compound exhibited anti-AChE activity with IC50 value of 23.4 μM.
Burden Sharing in CSDP Military Operations
Creators: name: Haesebrouck, Tim
name: Thiem, Alrik
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Military burden sharing has been a subject of repeated debates in NATO and the UN. Despite more modest goals, the European Union’s (EU) Common Security and Defense Policy (CSDP) has experienced no fewer difficulties in garnering men, money, and materiel. While this may not come as a surprise, the fact that some EU member states have carried disproportionate shares of the burden of CSDP operations is a puzzle that remains unaccounted for. We address this gap by analyzing determinants of contribution levels to CSDP operations. In employing an innovative multi-method design that combines insights from collection action theory with those from integrated theories of military burden sharing, our results indicate that EU countries tend to contribute in positive disproportion with their capabilities when they have a strong peacekeeping tradition and elections are distant. In contrast, they undercontribute when small trade volumes with the area of operations combine with a weak peacekeeping tradition.
O pensamento da diferença no «De divisione naturae» de Escoto Eriúgena
Creators: name: Silva, Carlos Henrique Do Carmo
Publisher: name: Didaskalia
Year: 1973

description: 1. Introdução ao problema da diferença no «De divisione naturae». 2. A «divisio» segundo Escoto Eriúgena. Contexto histórico. 3. A divisão como oposição. 4. Divisão e separação radical. 5. O quaternário da divisão. 6. Método analítico e critério de distinção. 7. A «Natura» e seus desenvolvimentos. 8. Conclusão: A especulação diferencial.
description: Didaskalia, v. 3 n. 2 (1973)
MyGene2 automated match report: KMT2A
Creators: name: Team, The MyGene2
Publisher: name: figshare
Year: 2017
Subjects: subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine

description: MyGene2.org is free, public, searchable & browsable website. Families with rare genetic conditions, clinicians, and researchers families who are interested in sharing health and genetic information can create MyGene2 profiles and use these to connect with other families, clinicians, and researchers who may have or be studying the same condition. If multiple MyGene2 profiles potentially match on a shared gene of interest, MyGene2 automatically generates a match report summarizing the information in these profiles. This automated match report is shared publicly to help facilitate further research and/or connections between the submitters of the MyGene2 profiles and other interested parties. This is an automated match report for KMT2A.