Additional file 1 of Circulating inflammatory biomarkers, adipokines and breast cancer risk—a case-control study nested within the EPIC cohort
Creators: name: Cairat, Manon
name: Rinaldi, Sabina
name: Navionis, Anne-Sophie
name: Romieu, Isabelle
name: Biessy, Carine
name: Viallon, Vivian
name: Olsen, Anja
name: Tjønneland, Anne
name: Fournier, Agnès
name: Severi, Gianluca
name: Kvaskoff, Marina
name: Fortner, Renée T.
name: Kaaks, Rudolf
name: Aleksandrova, Krasimira
name: Schulze, Matthias B.
name: Masala, Giovanna
name: Tumino, Rosario
name: Sieri, Sabina
name: Grasso, Chiara
name: Mattiello, Amalia
name: Gram, Inger T.
name: Olsen, Karina Standahl
name: Agudo, Antonio
name: Etxezarreta, Pilar Amiano
name: Sánchez, Maria-Jose
name: Santiuste, Carmen
name: Barricarte, Aurelio
name: Monninkhof, Evelyn
name: Hiensch, Anouk E.
name: Muller, David
name: Merritt, Melissa A.
name: Travis, Ruth C.
name: Weiderpass, Elisabete
name: Gunter, Marc J.
name: Dossus, Laure
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Additional file 1: Circulating inflammatory biomarkers and breast cancer risk in the EPIC prospective study: Supplementary Tables S1- S7 and Figures S1-S3. Table S1. Geometric mean values for inflammatory biomarkers in breast cancer cases and matched controls. Table S2. Associations between inflammatory biomarkers and breast cancer risk by age at diagnosis. Table S3. Associations between inflammatory biomarkers and breast cancer risk by breast cancer molecular subtypes. Table S4. Associations between inflammatory biomarkers and breast cancer risk by time between blood collection and diagnosis. Table S5. Associations between inflammatory biomarkers and breast cancer risk by body mass index. Table S6. Associations between inflammatory biomarkers and breast cancer risk by waist circumference. Table S7. Associations between inflammatory biomarkers and breast cancer risk among non-hormone users at blood collection. Table S8. Associations between IL-10 and breast cancer risk overall and according to menopausal status at blood collection, after excluding women with values of IL-10 below the LOQ. Table S9. Associations between TNF-α and breast cancer risk overall and according to menopausal status at blood collection, after excluding women with values of TNF-α below the LOQ. Figure S1. Flow chart of the study population. Figure S2. Association between leptin and breast cancer risk, overall and by menopausal status, allowing for nonlinear effects (restricted cubic spline). Figure S3. Association between leptin-to-adiponectin ratio and breast cancer risk, overall and by menopausal status, allowing for nonlinear effects (restricted cubic spline). Figure S4. Association between CRP with breast cancer risk, overall and by menopausal status, allowing for nonlinear effects (restricted cubic spline).