cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Type III events, flares and CMEs, in the extremely active period October-November 2003
Creators: name: Mitsakou, E.
name: Thanasa, M.
name: Preka-Papadema, P.
name: Moussas, X.
name: Hillaris, A.
name: Caroubalos, C.
name: Alissandrakis, C. E.
name: Tsitsipis, P.
name: Kontogeorgos, A.
name: Bougeret, J. -L.
name: Dumas, G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The type III observations trace the propagation of energetic electron populations through the Solar Corona which, more often than not, precede or are associated with energy release on the Sun. A sample of Type III bursts in the range 20-650 MHz during the period of extraordinary solar activity (20 October to 4 November 2003) recorded by the ARTEMIS-IV1 radio spectrograph is analysed; its parameters are compared with characteristics of associated flares (Ha and GOES SXR) and CMEs, observed in the same period and reported in the SGR and the LASCO archives respectively. In this report we attempt to establish a correlation between energetic particles and major manifestations of solar activity such as flares and CMEs.
description: Recent Advances in Astronomy and Astrophysics: 7th International Conference of the Hellenic Astronomical Society. AIP Conference Proceedings, Volume 848, pp. 234-237 (2006)
Additional file 2 of Discovery of a novel antibacterial protein CB6-C to target methicillin-resistant Staphylococcus aureus
Creators: name: Zhang, Haipeng
name: Chen, Jingrui
name: Liu, Yuehua
name: Xu, Qijun
name: Inam, Muhammad
name: He, Chengguang
name: Jiang, Xiuyun
name: Jia, Yu
name: Ma, Hongxia
name: Kong, Lingcong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2: Fig S1. (A) Sephadex G-75 elution profile of antibacterial protein CB6-C. (B) QAE-Sephadex A25 elution profile of antibacterial protein CB6-C. Fig S2. (A) HPLC elution profile of antibacterial protein CB6-C; (B) SDS-PAGE of antibacterial protein CB6-C. Lane M: high molecular marker, lane 1–3: Stained of the gel showing purified antibacterial protein CB6-C. Fig. S3. (A) Gram-stained photograph after MRSA has removed the cell wall. (B). Gram-stained photograph of untreated cells for MRSA.
Encontro Internacional «Palácios Islâmicos na Bacia do Mediterrâneo: séculos VIII-XIV»
Creators: name: G., R. V.
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
title: Rechtsrahmen virtueller Museumsbesuche
Creators: name: Morr, Khadija
name: Zerres, Thomas
name: Zerres, Christopher
Publisher: name: Hochschule Offenburg
Year: 2021
Subjects: subject: 340 Recht

description: Seit Jahrzehnten mussten Museen nicht mehr für so eine lange Zeit schließen wie zurzeit. Um trotz der Coronapandemie die Möglichkeit eines Museumsbesuches zu eröffnen, bieten viele Museen virtuelle Rundgänge an. So kann man beispielsweise ganz entspannt von Zuhause das Deutsche Museum in München besichtigen oder auch der Mona Lisa im Louvre einen Besuch abstatten und dies ganz ohne lange Wartezeiten oder großen Andrang. Die digitalen Angebote reichen von Videos, virtuellen Ausstellungsrundgängen, digitalen Bildergalerien oder Podcasts bis hin zu 360° Bildern und Videos, sowie Anwendungen, die auf Online-Spielen beruhen. Letzteres sorgt dafür, dass Besucher sich ähnlich wie bei Online-Spielen per Mausklick oder Pfeiltasten der Tastatur frei bewegen können und so die Möglichkeit haben, die Umgebung und dort interessante Objekte näher zu betrachten. Höchstwahrscheinlich war das Thema eines virtuellen Museumsbesuches nie aktueller als während der Coronapandemie, jedoch gab es auch schon vor der Pandemie viele Museen, die ihre Angebote für virtuelle Besucher geöffnet haben. Nicht nur der Zugang zu Kulturangeboten für die breite Masse war ein Grund für die Digitalisierung der Museen, auch der Einsturz des Kölner Stadtarchivs 2009 etwa zeigte, wie wichtig die Digitalisierung ist, um historische Werke im Falle einer Zerstörung nicht komplett zu verlieren. Denn auch wenn das Original nicht mehr verfügbar ist, können historische Werke bewahrt und der breiten Masse zugänglich gemacht werden. Dennoch wird dieses Thema auch nach der Coronapandemie nicht an Relevanz verlieren, da auch vorangegangene Epidemien zeigen, dass neue Strategien mittel- und langfristig notwendig sind und sein werden.
description: Arbeitspapiere für Marketing und Management; 57
Additional file 1 of Discovery of a novel antibacterial protein CB6-C to target methicillin-resistant Staphylococcus aureus
Creators: name: Zhang, Haipeng
name: Chen, Jingrui
name: Liu, Yuehua
name: Xu, Qijun
name: Inam, Muhammad
name: He, Chengguang
name: Jiang, Xiuyun
name: Jia, Yu
name: Ma, Hongxia
name: Kong, Lingcong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1: Table S1. Bacteria strains used in this study
Section-specific geometric error evaluation of airfoil blades based on digitized surface data
Creators: name: Khameneifar, Farbod
Publisher: name: University of British Columbia
Year: 2015

description: Manufactured aero-engine blades are normally inspected in sections. Given discrete section-specific data points, the related geometric error evaluation task for three-dimensional tolerances of the blades is challenging and not yet well studied by researchers. Particularly, the existing method shows limited effectiveness in detecting position error and difficulty in accurate estimation of orientation error of airfoil sections. Moreover, touch-probes on a coordinate measuring machine are traditionally used to collect sectional coordinate data, which is a lengthy process as the data is collected through probe contact with the blade surface. Blade manufacturers would rather use 3D laser scanning that can complete data acquisition much faster. However, this poses a new challenge to data analysis. The collected set of points, referred to as point cloud, is all over the surface rather than at the desired, pre-specified sections. Thus, generating reliable section-specific data from the massive, unorganized scanned data points remains a problem to be solved. This thesis first presents a new methodology for evaluating three-dimensional tolerances of airfoil sections based on reconstructing the airfoil profiles from section-specific data points. According to a given measurement uncertainty, a progressive curve fitting scheme is proposed to generate the airfoil profile that meets the uncertainty constraint. Subsequently, the profile is utilized in related feature extraction of the proposed error evaluation approach. The second part of the thesis focuses on generating the reliable section-specific data points from the complete surface scan. An adaptive surface projection of data points onto the pre-specified section plane is proposed. A localized surface-fitting scheme is devised for this purpose. The main challenge lies in the selection of local data points, referred to as local neighborhood, for surface fitting. In particular, with the non-uniform distribution of data points in a noisy point cloud, existing neighborhood selection methods lead to biased fitting results. To avoid bias, a method of establishing balanced local neighborhood for surface fitting is proposed. An automated technique is also presented for systematic identification of eligible points for projection. The proposed computational framework in this thesis enables fully automatic and accurate evaluation of geometric errors using the latest high-speed geometric inspection platform.
Meeting the demand of women affected by ongoing crisis: Increasing contraceptive prevalence in North and South Kivu, Democratic Republic of the Congo
Creators: name: Casey, Sara E.
name: Gallagher, Meghan C.
name: Dumas, Erin
name: Kakesa, Jessica
name: Mumbere Katsongo, Justin
name: Muselemu, Jean-Baptiste
Publisher: name: Columbia University
Year: 2019
Subjects: Contraception
Women--Health and hygiene
Reproductive health services
War

description: Context Over 20 years of conflict in the DRC, North and South Kivu have experienced cycles of stability and conflict, resulting in a compromised health system and poor sexual and reproductive health outcomes. Modern contraceptive use is low (7.5%) and maternal mortality is high (846 deaths per 100,000 live births). Program partners have supported the Ministry of Health (MOH) in North and South Kivu to provide good quality contraceptive services in public health facilities since 2011. Methods Cross-sectional population-based surveys were conducted in the program areas using a two-stage cluster sampling design to ensure representation in each of six rural health zones. Using MOH population estimates for villages in the catchment areas of supported health facilities, 25 clusters in each zone were selected using probability proportional to size. Within each cluster, 22 households were systematically selected, and one woman of reproductive age (15–49 years) was randomly selected from all eligible women in each household. Results Modern contraceptive prevalence among women in union ranged from 8.4% to 26.7% in the six health zones; current use of long-acting or permanent method (LAPM) ranged from 2.5% to 19.8%. The majority of women (58.9% to 90.2%) reported receiving their current method for the first time at a health facility supported by the program partners. Over half of women in four health zones reported wanting to continue their method for five years or longer. Conclusion Current modern contraceptive use and LAPM use were high in these six health zones compared to DRC Demographic and Health Survey data nationally and provincially. These results were accomplished across all six health zones despite their varied socio-demographic characteristics and different experiences of conflict and displacement. These findings demonstrate that women in these conflict-affected areas want contraception and will choose to use it when good quality services are available to them.
Multifragmentation at the balance energy of mass asymmetric colliding nuclei
Creators: name: Goyal, Supriya
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Using the quantum molecular dynamics model, we study the role of mass asymmetry of colliding nuclei on the fragmentation at the balance energy and on its mass dependence. The study is done by keeping the total mass of the system fixed as 40, 80, 160, and 240 and by varying the mass asymmetry of the ($η$ = $\frac{A_{T}-A_{P}}{A_{T}+A_{P}}$; where $A_{T}$ and $A_{P}$ are the masses of the target and projectile, respectively) reaction from 0.1 to 0.7. Our results clearly indicate a sizeable effect of the mass asymmetry on the multiplicity of various fragments. The mass asymmetry dependence of various fragments is found to increase with increase in total system mass (except for heavy mass fragments). Similar to symmetric reactions, a power law system mass dependence of various fragment multiplicities is also found to exit for large asymmetries.
description: 5 pages, 6 figures
Indole prenyltransferases : mechanistic studies and inhibitor design
Creators: name: Mahmoodi, Niusha
Publisher: name: University of British Columbia
Year: 2015

description: The cyclic dipeptide N-prenyltransferase (CdpNPT) catalyzes the reverse C-3 prenylation of a variety of cyclic dipeptides and benzodiazepinediones. A previous study misassigned the structure of the product of this reaction. In this work, the true product of the CdpNPT-catalyzed reaction between cyclo-L-Trp-L-Trp and dimethylallyl diphosphate (DMAPP) is identified as a C-3 reverse prenylated species. Furthermore, the non-enzymatic Cope/aza-Cope rearrangement of the CdpNPT product was examined under acidic conditions. Our results indicated that only the aza-Cope rearrangement onto the N-1 position of the indole ring can occur and no Cope rearrangement onto the C-4 position was observed. These results suggest that in the absence of an enzyme active site, the aza-Cope rearrangement is preferred over the Cope rearrangement. Brevianamide F prenyltransferase (FtmPT1) catalyzes the C-2 normal prenylation of brevianamide F (cyclo-L-Trp-L-Pro). A mechanism involving a direct C-2 attack was proposed for this reaction. However, the structural analysis of FtmPT1, as well as studies of alternate substrates and mutant enzymes suggested that a different mechanism involving an initial C-3 reverse prenylation followed by a rearrangement may be operative. In this work, we investigated the reactivity of FtmPT1 with tryptophan and cyclo-L-Trp-L-Trp, as well as two alternate substrates: 5-hydroxybrevianamide F and 2-methylbrevianamide F. The isolated products were reverse prenylated at C-3 and normal prenylated at N-1, C-2, C-3, or C-4. The formation of these products can be rationalized through mechanisms involving either an initial C-3 normal or C-3 reverse prenylation as the first step of catalysis. 4-Dimethylallyltryptophan synthase is an aromatic prenyltransferase that catalyzes an electrophilic aromatic substitution reaction between DMAPP and L-tryptophan. The reaction is believed to proceed via the dissociation of DMAPP to form a dimethylallyl cation/phosphate ion pair. An inhibitor containing a guanidinium moiety appended to a phosphorylated phosphonate was designed in order to mimic the transition state for the dissociation of DMAPP into an allylic carbocation and pyrophosphate. This compound was found to serve as a potent competitive inhibitor (submicromolar Ki value) of the enzyme 4-DMATS.
António Barroso, bispo de Meliapor (1897-1899): construtor da unidade
Creators: name: Azevedo, Carlos A. Moreira
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
Additional file 5 of A spatiotemporal atlas of the lepidopteran pest Helicoverpa armigera midgut provides insights into nutrient processing and pH regulation
Creators: name: Ioannidis, Panagiotis
name: Buer, Benjamin
name: Ilias, Aris
name: Kaforou, Sofia
name: Aivaliotis, Michalis
name: Orfanoudaki, Georgia
name: Douris, Vassilis
name: Geibel, Sven
name: Vontas, John
name: Denecke, Shane
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 5.
title: Der Markt von Online-Apotheken in Deutschland – Eine rechtlich fokussierte Analyse
Creators: name: Fritz, Kim
name: Zerres, Thomas
name: Zerres, Christopher
Publisher: name: Hochschule Offenburg
Year: 2021
Subjects: subject: 330 Wirtschaft

description: Über Jahrhunderte hinweg erfolgte die Versorgung mit Arzneimitteln über stationäre Apotheken. Dort besteht ein direkter Kontakt zu Apothekern sowie Pharmazeutisch-technischen Assistenten (PTA). Bereits in den letzten Jahren hat sich dieser traditionell verankerte Ansatz deutlich gewandelt. Durch die bundesweite Legalisierung des Arzneimittelversandhandels gemäß § 43 Abs. 1 Arzneimittelgesetz (AMG) zu Beginn des Jahres 2004 sind verschreibungspflichtige und nicht verschreibungspflichtige Arzneimittel fortan nur noch wenige Klicks entfernt und können jederzeit bequem von Zuhause aus an eine Wunschadresse geordert werden. Unerheblich, ob aus gesundheitlichen oder zeitlichen Beweggründen oder aufgrund des Komforts, die Versorgung mit Arzneimitteln über Online-Apotheken erleichtert den Alltag für eine Vielzahl von Menschen. Ein wesentlicher Meilenstein für das Aufkommen der Online-Apotheke war die Digitalisierung des Apothekenmarktes. Der E-Commerce ist dabei als Innovationstreiber ein wichtiger Aspekt, denn er ist verstärkt auf dem Vormarsch und gewinnt immer mehr an Bedeutung. Moderne Vertriebsstrukturen und die breitere Adressatenorientierung durch das Internet ermöglichen es Online-Apotheken, auf größere Kundenkreise zurückzugreifen. Dies bestätigt eine kürzlich durchgeführte Studie des Bundesverbands Informationswirtschaft, Telekommunikation und neue Medien (Bitkom). Danach kaufen 58 Prozent der Deutschen regelmäßig ihre Arzneimittel in einer Online-Apotheke. Insoweit kann davon ausgegangen werden, dass dieser Markt über eine starke Nachfrage verfügt. Weiteren Aufschwung erleben Online-Apotheken derzeit durch die COVID-19-Pandemie. Aufgrund von Social Distancing wird der Arzneimittelkauf im Internet vermehrt angenommen. Digitale Lösungen, wie das elektronische Rezept (E-Rezept), werden die Relevanz von Online-Apotheken zukünftig weiter antreiben.
description: Arbeitspapiere für Marketing und Management; 58
Numerical investigation of the flexural performance of reinforced concrete beams strengthened with textile reinforced mortar
Creators: name: Rakhshani, Sassan
Publisher: name: University of British Columbia
Year: 2015

description: Textile composite materials with cement based adhesive have been developed recently by the construction industry for strengthening of concrete structures. Textile reinforced mortar (TRM) materials are known to be more compatible with the concrete substrate and can provide a substantial gain in compressive strength and deformability of the structure, as well as a better performance at high temperatures and during fire when compared to other strengthening materials such as fibre reinforced polymer. In this study, the effect of select physical (thickness) and mechanical (modulus of elasticity) properties of different types of TRM reinforcement (carbon, poly-phenylene-2,6-benzobisoxazolem (PBO), and steel fibres) with different reinforcement ratio has been investigated on the ensuing flexural performance of RC beams, by means of a finite element (FE) model. The response variables were the beam’s load carrying capacity, mid-span deflection, effective stiffness, and failure mode. Results of the numerical simulation and factorial design analysis indicated that the application of TRM sheets can be effective in strengthening the RC beams with a statistical significance of α=5%, under all of the above-mentioned response variables, in some cases as much as 109% when compared to the unstrengthend RC beam.
José de Sousa Amado e as lutas contra a heterodoxia social e religiosa: um percurso bibliográfico
Creators: name: Pinto, Paulo Mendes
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
title: Portfolioanalysen im Vergleich
Creators: name: Gramlich, Samantha
name: Obreiter, Nadine
name: Otomierczyk, Laura
name: Storz, Leonie
Publisher: name: Hochschule Offenburg
Year: 2021
Subjects: subject: 330 Wirtschaft

description: Aufgrund der zunehmenden Internationalisierung, veränderten Einstellungen und Entscheidungen der Verbraucher:innen hinsichtlich der Nachhaltigkeit, der Ausbreitung des Internets sowie der fortschreitenden Digitalisierung entsteht eine wachsende Dynamik von Märkten. Eine Möglichkeit, dadurch bedingten und schnelllebigen Veränderungen als Unternehmen gerecht zu werden, bieten die Instrumente des strategischen Marketing-Controllings im Rahmen der Unternehmenssteuerung. Dazu gehören die Methoden der Portfolioanalyse, welche, wie der Begriff bereits angibt, das Portfolio eines Unternehmens bewerten. Basierend auf der Bewertung der Tätigkeitsfelder können fundierte strategische Managemententscheidungen bezüglich des Portfolios getroffen werden. Bereits eine Studie aus dem Jahr 2013 zeigt, dass 78 % der befragten Unternehmen strategische Produktportfolioanalysen als strategisches Marketinginstrument einsetzen. Davon geben 35 % an, diese regelmäßig einzusetzen, die restlichen 43 % lediglich unregelmäßig.3 Es lässt sich feststellen, dass, wie bereits erwähnt, verschiedene Methoden zur Auswahl stehen, darunter die Marktwachstum-/Produktlebenszyklus-Portfolioanalyse, die Marktwachstum-/Marktanteils-Portfolioanalyse, die Marktattraktivitäts-/Wettbewerbsvorteils-Portfolioanalyse und die Marktwachstum-/Kostendeckungsgrad-Portfolioanalyse, bei welchen verschiedene Aspekte einfließen und gegenübergestellt werden. Allerdings stellt die Entscheidung über die Eignung einer Anwendung dieser Methoden und die Bewertung derer Ergebnisse eine Herausforderung dar. Letztere können die Einschätzung der strategischen Ausgangssituation und die strategische Ausrichtung eines Unternehmens substanziell beeinflussen und somit sowohl positive als auch negative Auswirkungen auf den gesamten Unternehmenserfolg haben.
description: Arbeitspapiere für Marketing und Management; 59
Beyond full-time equivalents : gender differences in activity and practice patterns for BC's primary care physicians
Creators: name: Hedden, Lindsay Kathleen
Publisher: name: University of British Columbia
Year: 2015

description: There is widespread sentiment that British Columbia (BC) is facing a substantial shortage and a maldistribution of primary care physicians (PCPs). The increasing proportion of PCPs who are women has been cited as contributing to this complex problem, based largely on assumptions that female physicians work less, take time off to raise children, and retire earlier compared to their male counterparts. However, Canadian evidence supporting these assertions is lacking. This thesis uses population-based, administrative data resources to undertake a comprehensive assessment of the potential impact of the increasing feminization of BC’s PCP workforce, focusing on gender differences in career trajectories, billing patterns, activity, patient and service mix, and scopes of practice. It consists of four components: a systematic review of existing literature; a longitudinal analysis of gender-specific remuneration and activity; a comparison of patient populations seen by male and female PCPs; and an examination of gender-driven differences in selected aspects of primary care practice. The results of these analyses suggest that female PCPs have lower total remuneration, see fewer patients, and deliver fewer services annually compared to male PCPs; however, this gender-related activity gap is narrowing over time as male physicians are reducing their activity levels. Female physicians derive more of their income from direct clinical care delivery (rather than from clinical or non-clinical incentive payments) when compared to male physicians. The proportion of physicians’ total compensation derived from direct care delivery is declining, particularly for male physicians. Results also show that female physicians have smaller overall practices and disproportionately treat younger, healthier patients. They are less likely to provide off-site and after-hours care, but more likely to include obstetrical care in their practices. This thesis demonstrates that gender differences in primary care practice go beyond salary and service volumes. More robust measures of physician supply that address the implications of gender differences in patient mix, service mix, and practice style need to be developed as more evidence in these areas becomes available. The gender division of unpaid care work, household responsibilities, and work-life balance, and the implications for health human resource planning all deserve careful attention in future work.
Frontiers in Academic Ebook Delivery: Deploying the Library Driven Platform
Creators: name: Cartolano, Robert T.
name: DiPasquale, Emma
name: English, James
Publisher: name: Columbia University
Year: 2019
Subjects: Academic libraries
Libraries
Library science
Electronic books

description: Explore new and emerging initiatives in academic ebook delivery from University of Michigan Press, including their Fulcrum platform, and LYRASIS' work to expand SimplyE to academic titles.
The Role of Food for Special Medical Purposes in Managing Malnutrition – A Dietitians Perspective
Creators: name: Mooney, A
name: Sanecka, M
name: Walsh, S
name: Fox, S
name: O'Donovan, C.B
name: Erraught, C
name: Stack, M
Publisher: name: Zenodo
Year: 2023
Subjects: subject: Food for Special Medical Purposes (FSMPs)
subject: Foods for Specific Groups (FSGs)
subject: Malnutrition
subject: Disease related malnutrition (DRM)
subject: Dietitians
subject: Regulation
subject: Reimbursement
subject: Oral Nutritional Supplements (ONS)
subject: http://id.agrisemantics.org/gacs/C3929
subject: http://id.agrisemantics.org/gacs/C743
subject: http://id.agrisemantics.org/gacs/C1966
subject: http://id.agrisemantics.org/gacs/C1389

description: This poster was prepared for the Irish Nutrition and Dietetic Institute (INDI) Fresenius Kabi Symposium 2023 in Trinity College Dublin. The target audience for this particular conference are healthcare professionals. The results from this poster were based on a survey conducted of Irish Dietitians and their attitudes towards Food for Special Medical Purposes (FSMPs) for the management of malnutrition. These products are required to be notified to the competent authority who is the Food Safety Authority of Ireland (FSAI) in Ireland.
description: IE, PDF, phn@fsai.ie
description: {"references": ["National Institute for Health and Care Excellence. (2017) [Available at: https://www.nice.org.uk/guidance/cg32 ].", "HSE. Prescribing Pathway for the Initiation and Renewal of Standard Oral Nutritional Supplements (ONS) for Adults Living in the Community. (2019) [Available at: prescribing pathway and list.pdf (hse.ie) ].", "HSE. Malnutrition in Ireland. [Available at: https://www.hse.ie/eng/services/list/2/primarycare/community-funded-schemes/nutrition-supports/malnutrition-in-ireland/ ].", "Regulation (EU) No 609/2013. [Available at: https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX:32013R0609 ].", "HSE. How to use Oral Nutritional Supplements. [Available at: how-to-use-oral-nutritional-supplements.pdf (hse.ie) ].", "Braun V, Clarke V. Using thematic analysis in psychology. Qualitative research in psychology. 2006;3(2):77-101."]}
Graphene: A sub-nanometer trans-electrode membrane
Creators: name: Garaj, S.
name: Hubbard, W.
name: Reina, A.
name: Kong, J.
name: Branton, D.
name: Golovchenko, J. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: Isolated, atomically thin conducting membranes of graphite, called graphene, have recently been the subject of intense research with the hope that practical applications in fields ranging from electronics to energy science will emerge. Here, we show that when immersed in ionic solution, a layer of graphene takes on new electrochemical properties that make it a trans-electrode. The trans-electrode's properties are the consequence of the atomic scale proximity of its two opposing liquid-solid interfaces together with graphene's well known in-plane conductivity. We show that several trans-electrode properties are revealed by ionic conductivity measurements on a CVD grown graphene membrane that separates two aqueous ionic solutions. Despite this membrane being only one to two atomic layers thick, we find it is a remarkable ionic insulator with a very small stable conductivity that depends on the ion species in solution. Electrical measurements on graphene membranes in which a single nanopore has been drilled show that the membrane's effective insulating thickness is less than one nanometer. This small effective thickness makes graphene an ideal substrate for very high-resolution, high throughput nanopore based single molecule detectors. Sensors based on modulation of graphene's in-plane electronic conductivity in response to trans-electrode environments and voltage biases will provide new insights into atomic processes at the electrode surfaces.
description: Submitted 12 April 2010 to Nature, where it is under review
Pensar Lacordaire a partir de Portugal: a propósito de um colóquio realizado em Lisboa, de 2 a 5 de Maio de 2003
Creators: name: Ferreira, António Matos
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
Human Rights Advocates Program 30th Anniversary Report
Creators: name: Woods II, Samuel Kofi
name: Ancheita Pagaza, Alejandra
name: Parong, Aurora Corazon A.
name: Uhaa, Sylvester
name: Binda, Elvis Mbembe
name: Odur, Betty Lee
name: Dyantyi, Carol
name: Miiro, Michael
name: Savic, Marijana
name: Muwonge, Mulshid
name: Balakrishnan, Chitra
name: Manu, Aehshatou
name: Adhiambo, Esther
name: Djiraibe, Delphine
name: Sherpa, Chhing Lamu
name: Kaguri, Twesigye Jackson
name: Pervanic, Kemal
name: Santos, Carlos
name: Asúnsolo Morales, Carlos R.
name: Hudaya, Inna
name: Lako, Benson Khemis Soro
name: Imoh, Colins Edozie
name: Tandia, Bakary
name: Matsikure, Samuel
name: Kaseketi, Musola Cathrine
name: Grepo, Stephanie V.
Publisher: name: Columbia University
Year: 2019
Subjects: Human rights
Human rights workers
Human rights--Study and teaching
Human rights advocacy

description: This handbook was created to share the experiences of alumni of the Human Rights Advocates Program at the Institute for the Study of Human Rights, Columbia University, with aspiring human rights advocates around the globe.
Microbial transformation of dehydroepiandrosterone (DHEA) by some fungi
Creators: name: Yildirim, Kudret
name: Kuru, Ali
name: Keskin, Semra Yılmazer
name: Ergin, Sinan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: In this work, biotransformations of dehydroepiandrosterone (DHEA) 1 by Ulocladium chartarum MRC 72584, Cladosporium sphaerospermum MRC 70266 and Cladosporium cladosporioides MRC 70282 have been reported. U. chartarum MRC 72584 mainly hydroxylated 1 at C-7α and C-7β, accompanied by a minor hydroxylation at C-4β, a minor epoxidation from the β-face and a minor oxidation at C-7 subsequent to its hydroxylations. 3β,7β-Dihydroxy-5β,6β-epoxyandrostan-17-one 6, 3β,4β,7α-trihydroxyandrost-5-en-17-one 7 and 3β,4β,7β-trihydroxyandrost-5-en-17-one 8 from this incubation were identified as new metabolites. C. sphaerospermum MRC 70266 converted some of 1 into a 3-keto-4-ene steroid and then hydroxylated at C-6α, C-6β and C-7α, accompanied a minor 5α-reduction and a minor oxidation at C-6 following its hydroxylations. C. sphaerospermum MRC 70266 also hydroxylated some of 1 at C-7α and C-7β. C. cladosporioides MRC 70282 converted almost half of 1 into a 3-keto-4-ene steroid and then hydroxylated at C-6α and C-6β. C. cladosporioides MRC 70282 also reduced some of 1 at C-17.
Enantioselective reduction of heterocyclic ketones with low level of asymmetry using carrots
Creators: name: Machado, Naira Vieira
name: Omori, Álvaro Takeo
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: A whole spectrum of biocatalysts for asymmetric reduction of prochiral ketones is well known including the Daucus carota root. However, this type of reaction is still challenging when pro-chiral ketones present low level of asymmetry, like heterocyclic ketones. In this work, 4,5-dihydro-3(2H)-thiophenone (1), 2-methyltetrahydrofuran-3-one (2), N-Boc-3-pyrrolidinone (3), 1-Z-3-pyrrolidinone (4) and 1-benzyl-3-pyrrolidinone (5) were studied in order to obtain the respective enantioselective heterocyclic secondary alcohols. Except for 5, the corresponding alcohols were obtained in high values of conversion and with high selectivity. In order to circumvent the low isolated yield of the corresponding chiral alcohol from 2, we observed that the use of carrots in the absence of water is feasible. Addition of co-solvents was needed to the water-insoluble ketones 3 and 4. Comparatively, baker’s yeast was used for bio reductions of 1, 3 and 4. And in terms of conversion, selectivity and work-up, the use of carrots were a more efficient biocatalyst, as well as a viable method for obtaining 5-member heterocyclic secondary alcohols.
Androgens and neuroplasticity : contributions to the pathogenesis and treatment of depression
Creators: name: Wainwright, Steven R.
Publisher: name: University of British Columbia
Year: 2015

description: Depression is a devastating neuropsychiatric disease that has profound effects on neural structure and function, however the pathogenesis and modes of effective treatment remain poorly understood. Stress is the primary preceding factor in depression, leading to profound deficits in neurophysiology, particularly in the hippocampus. Depressed patients show reduced hippocampal neuroplasticity, while antidepressant treatment enhances both neurogenesis and the expression of proteins that mediate plasticity such as the polysialylated form of the neural cell adhesion molecule (PSA-NCAM). Interestingly, men are half as likely as women to develop depression, where androgens appear to confer resiliency in males, as hypogonadal men are more likely to develop depression and supplementation of testosterone shows antidepressant efficacy. Little is known about the neurological underpinnings of this profound sex difference, however androgens influence the stress response and enhance hippocampal neurogenesis. The experiments in this thesis aimed to examine the role of androgens in the pathogenesis and treatment of depression using an animal model, with a specific eye toward the impact on hippocampal neurogenesis and neuroplasticity, and whether neuroplasticity mediated through PSA-NCAM is essential to antidepressant efficacy. In Chapter 2, surgically-induced hypogonadism potentiates the expression of depressive-like endophenotypes in male rodents within a chronic unpredictable stress (CUS) model of depression. Hypogonadal males showed potentiated behavioural, endocrine, and neurophysiological depressive-like phenotypes, including reductions in hippocampal neurogenesis and the expression of PSA-NCAM, compared to intact males. In Chapter 3, the hypogonadism-induced susceptibility to depressive-like phenotypes following CUS is largely inhibited by supplementation with testosterone. Testosterone treatment ameliorated physiological and endocrine phenotypes while showing independent antidepressant-like effects and facilitating the efficacy of an antidepressant drug in some measures. In Chapter 4, the enzymatic cleavage of the polysialic acid moiety from NCAM completely inhibits the behavioural efficacy of antidepressant treatment, while also serving to attenuate the survival of newly generated hippocampal neurons. Collectively, this body of research demonstrates the protective effects of androgens against the development of depression in males, coinciding with enhanced hippocampal neuroplasticity, and delineates an essential role for neuroplasticity mediated through PSA-NCAM in antidepressant action.
Religião, sociedade e vintismo no Jornal Astro da Lusitânia
Creators: name: Pinheiro, Susana Marta Delgado
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
Roubos, extravios e descaminhos nas livrarias conventuais portuguesas após a extinção das Ordens Religiosas: um quadro impressivo
Creators: name: Barata, Paulo J. S.
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
O papel dos arquivos diocesanos na construção do sistema de arquivos da Igreja Católica: o caso da Diocese de Bilbau
Creators: name: Arahuetes, Anabela Barroso
Publisher: name: Lusitania Sacra
Year: 2004

description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
Accurate prediction of gene expression by integration of DNA sequence statistics with detailed modeling of transcription regulation
Creators: name: Vilar, Jose M. G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Biological Physics (physics.bio-ph)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Biological sciences
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Gene regulation involves a hierarchy of events that extend from specific protein-DNA interactions to the combinatorial assembly of nucleoprotein complexes. The effects of DNA sequence on these processes have typically been studied based either on its quantitative connection with single-domain binding free energies or on empirical rules that combine different DNA motifs to predict gene expression trends on a genomic scale. The middle-point approach that quantitatively bridges these two extremes, however, remains largely unexplored. Here, we provide an integrated approach to accurately predict gene expression from statistical sequence information in combination with detailed biophysical modeling of transcription regulation by multidomain binding on multiple DNA sites. For the regulation of the prototypical lac operon, this approach predicts within 0.3-fold accuracy transcriptional activity over a 10,000-fold range from DNA sequence statistics for different intracellular conditions.
description: 15 pages, 5 figures
Additional file 6 of A spatiotemporal atlas of the lepidopteran pest Helicoverpa armigera midgut provides insights into nutrient processing and pH regulation
Creators: name: Ioannidis, Panagiotis
name: Buer, Benjamin
name: Ilias, Aris
name: Kaforou, Sofia
name: Aivaliotis, Michalis
name: Orfanoudaki, Georgia
name: Douris, Vassilis
name: Geibel, Sven
name: Vontas, John
name: Denecke, Shane
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 6.
The impact of a difficult birth on mothering over time
Creators: name: Rollison, Lynn
Publisher: name: University of British Columbia
Year: 2015

description: Existing literature about childbirth does not clearly address the relationship between women’s experiences of “difficult birth” and the meanings women create from those events. This research focuses on women who identified they experienced a difficult birth, as opposed to a traumatic birth a topic that has received some attention. The experiences of 12 women and how a difficult birth affects the mother and how she creates meaning about it over time were explored. I focus on the women’s perceptions about their ability to mother and on the relationship between the infant and the family. The women’s stories are analyzed through ethnographic-informed methods with a feminist perspective. The absence of information about women’s experience of difficult birthing and their subsequent mothering is due to the silencing of their voice and a lack of investigation into their concerns during childbirth. This research identifies six themes common to the women’s stories: health care professionals who have the dominant or authorial voice; hospital staff, who share little or no information with the women about their care; women, who are made to feel inadequate by HCPs; women, who experience an absence or a lack of care or assessment; significant others who abandon the women; and, women who experience ethical situations concerning their own care and that of their infant. I conclude that mothering over time is deeply affected by the experience of difficult birth, despite the varied and diverse situations and the contexts of difficult births.
Production of hydroxytyrosol from hydroxylation of tyrosol by Rhodococcus pyridinivorans 3HYL DSM109178
Creators: name: Anissi, Jaouad
name: Sendide, Khalid
name: Ouardaoui, Abdelkrim
name: Benlemlih, Mohammed
name: Hassouni, Mohammed El
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology

description: Hydroxytyrosol (4-(2-hydroxyethyl)-1,2-benzenediol) is the most known bioactive compound from the plant Olea europaea (olive tree). To date, few biocatalysis processes allowing efficient production of hydroxytyrosol from potential substrates including, tyrosol (2-(4-hydroxy) phenyl ethanol) and tyrosine have been reported. In this paper, we report for a Gram-positive bacterium that produces hydroxytyrosol via conversion of tyrosol and/or L-tyrosine, identified as a Rhodococcus pyridinivorans based on phenotypic characteristics and 16S rDNA sequence, and designated R. pyridinivorans strain 3HYL DSM109178. Interestingly, strain 3HYL shows an outstanding production of hydroxytyrosol from tyrosol up to 16.4 ± 0.23 mmol/L with high kinetic parameters exceeding the reported values. However, a slight downstream metabolism of the product is assigned to the wild-type strain during the stationary phase of growth. The plasmid-cured strain was obtained using random chemical mutagenesis, designated R. pyridinivorans 3HYL-AO, and was able to produce hydroxytyrosol, with yields up to 21.75 ± 0.34 mmol/L. Moreover, the plasmid-cured strain exhibited a significant reduction in the transformation to its acetic acid forms compared to the wild-type strain as depicted by HPLC analysis. Comparison of kinetic data of the bioconversion/accumulation process between the wild type and mutant strain, in the presence and absence of L-tyrosine, and thus suggesting the occurrence of an upstream pathway for synthesis of tyrosol via (L)-tyrosine.
Cannabis and aggression : differentiating reactive and instrumental aggression
Creators: name: Carroll, Christopher Ryan
Publisher: name: University of British Columbia
Year: 2015

description: My thesis explored the relation between cannabis use (CU) and two distinct subtypes of aggression. Substantial prior research has examined the association between CU and aggression; however, empirical evidence has not yet provided a clear or complete picture of this relationship. This may be due to the fact that to date no studies have considered the important distinction between instrumental aggression (IA) and reactive aggression (RA). The aim of this study was to differentiate these subtypes of aggression while controlling for covariates such as psychopathy and trait aggression which has the potential to reconcile the apparently contradictory findings in the literature. Also of interest was the role that gender plays in the relationship between cannabis and IA/RA. Samples from three different populations, who all completed a series of self-report questionnaires, were examined for this study. The sample from the university population consisted of 427 participants, the sample from the online population consisted of 434 participants, and the sample from the treatment population consisted of 68 participants. The data were analysed using independent samples t tests, hierarchical multiple regressions, and two-way ANOVAs. The results from all three samples indicated that there is little to no relation between CU and IA/RA. In cases where a relation was found, it disappeared when accounting for psychopathy and trait aggression. These findings were consistent across all frequencies of CU. Furthermore, the results showed that there was no interaction between gender and any frequency of CU when looking at the relation with IA/RA. Collectively, these findings indicate that CU is not associated with aggressive behaviour and propose answers to the question of why there is such differing findings in the existing literature. The public health impact of CU remains controversial and these findings have important theoretical, methodological, and clinical implications.
A oposição católica ao Marcelismo (1968-1974)
Creators: name: Almeida, João Miguel
Publisher: name: Lusitania Sacra
Year: 2004

description: O artigo analisa a evolução das relações entre a Santa Sé, o episcopado português, o Governo do Estado Novo e a oposição católica durante o período do Marcelismo (1968-1974). É discutida a operacionalidade de conceitos como «oposição católica» e «católicos progressistas». As características daquela e destes são pensadas à luz dos condicionalismos da guerra colonial e das correntes ideológicas e teológicas dos anos 60 e 70. O novo fôlego do regime é visto por alguns católicos vindos da oposição como uma possibilidade de transição pacífica para a democracia mas também suscita, desde o início, uma radicalização de posições de «católicos progressistas».
description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento
A Comunidade de Taizé e o Concílio de Jovens (1970-79): uma primeira abordagem ao impacto da experiência de Taizé na dinâmica religiosa portuguesa
Creators: name: Revez, Jorge
Publisher: name: Lusitania Sacra
Year: 2004

description: A Comunidade de Taizé (França), fundada por Roger Schutz, representa desde os anos 40 uma referência fundamental no seio do movimento ecuménico. O Concílio de Jovens (1970-79), dinâmica religiosa animada pela comunidade, desempenhou um papel essencial como catalisador da universalização da experiência ecuménica de Taizé. Neste processo de renovação da vivência cristã, sobretudo da pastoral juvenil, destaca-se um indelével impacto na situação religiosa de diversos países. Neste artigo procuram-se avaliar de forma preliminar os matizes desse relacionamento entre Taizé e Portugal.
description: Lusitania Sacra, n. 16 (2004): Mutações Religiosas na Época Contemporânea: Figuras e Pensamento