cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
ASL Signbank
Creators: name: Hochgesang, Julie
name: Crasborn, Onno
name: Lillo-Martin, Diane
Publisher: name: figshare
Year: 2019
Subjects: classificationCode: 470499
subject: Linguistics not elsewhere classified

description: Reference: Julie A. Hochgesang, Onno Crasborn, and Diane Lillo-Martin. (2017-2020) ASL Signbank. New Haven, CT: Haskins Lab, Yale University. https://aslsignbank.haskins.yale.edu/

ASL Signbank is a collection of ASL signs linked with ID glosses.
Public access allows you to view videos of ASL signs along with translation equivalents (or keywords). Just go ahead and start browsing by clicking on "show all signs" under the "Signs" tab above.
If you register with an account, you will have access to more detailed information per sign. If you have a login account, go ahead and log in by clicking on the login button above. If you need one, please contact us.
NOTE: Online registration is currently not working. Please contact Julie dot Hochgesang at Gallaudet dot edu to request an account.
ASL Signbank can be linked with ELAN! Go ahead and use the ECV link here - https://aslsignbank.haskins.yale.edu/static/ecv/asl.ecv

To see how to link the ECV and to use the ASL Signbank as a lexicon service, please see this video by Onno Crasborn or the ELAN manual.

To learn more about the freely available ASL Signbank and the project it is affiliated with - SLAAASh - please click on the "about" tab above.
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Language, Terminology, and Cultural Appropriation in Queer Discourse
Creators: name: Abbas, Kaif
name: Visha, Akhil
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Humanities
subject: FOS: Humanities

description: This paper explores the complex relationships between language, terminology, and cultural appropriation in the context of queer discourse. It is impossible to overestimate the importance of language for queer groups, which reflect a wide range of identities and experiences. Language is essential for self-expression, identity formation, and community cohesiveness. However, conversations on cultural appropriation bring difficulty to the use of terminology in queer discourse because of the complex link between language, identity, and respect. One area of focus is the power dynamics present in terminology, which illuminates how language may marginalize or empower members of the queer community. The study acknowledges language's flexibility and reactivity to the always-shifting terrain of identities and expressions as it delves further into the evolutionary nature of language in the queer setting. The investigation of the effects of cultural appropriation on the queer community is at the heart of the analysis. The goal of the article is to examine the effects of co-opting or misrepresenting queer culture on identity development, community cohesiveness, and the larger conversation about queer experiences. This paper aims to provide a deeper understanding of the complex relationship between language, identity, and respect in queer discourse by navigating these complexities and shedding light on the difficulties associated with cultural appropriation as well as the power dynamics present in the terminology used by queer communities.
Marianna Charitonidou, "Lina Bo Bardi and Carlo Pagani's Casa sul Mare di Sicilia and the Mediterranean House: Mythology and Nature", SAH 2025 Annual International Conference
Creators: name: Charitonidou, Marianna
Publisher: name: Humanities Commons
Year: 2024

description: The paper explores the conception of the Mediterranean house in Lina Bo Bardi and Carlo Pagani's ‘Casa sul Mare di Sicilia’ – a theoretical project by Lina Bo Bardi designed for Domus in 1940. It places particular emphasis on Bo Bardi’s essay entitled “Architecture and Nature: The House in the Landscape” (1943), where she expresses her admiration for the typology of the Mediterranean house: “The world is full of examples of the perfect correspondence between this architecture and the environment in which human lives unfold, but none is so succinct as the Mediterranean house, none so pure and perfectly integrated into the earth and the landscape, so consonant with the life going on within and around it”. These characteristics of the Mediterranean house are very present in the ‘Casa sul Mare di Sicilia’. Bo Bardi and Pagani aimed to integrate the house into the landscape and the cultural context of Sicily, which is characterised by the strong presence of the mythology of Magna Graecia. Among the core characteristics of the ‘Casa sul Mare di Sicilia’ are its patio, its Mediterranean atmosphere, its respect for the natural and cultural context, the interest in vernacular anonymous architecture, and its use of the symbolic and archetypal features of mythological figures, such as Ulysses and his dog, and Hermes of Zeus’s “Askraios” in its drawings. The paper examines how Bo Bardi and Pagani related the integration of the Mediterranean house in the landscape to the concept of Magna Graecia, and how they turn the landscape into the very device that connects architecture to the myth of the archetype in the Mediterranean vernacular. At the centre of the reflections developed in the paper is their conviction that “architecture must be the key to the landscape”, transforming into the landscape, and becoming landscape itself.
Marianna Charitonidou, "Lina Bo Bardi and Carlo Pagani's Casa sul Mare di Sicilia and the Mediterranean House: Mythology and Nature", SAH 2025 Annual International Conference
Creators: name: Charitonidou, Marianna
Publisher: name: Society of Architectural Historians
Year: 2024

description: The paper explores the conception of the Mediterranean house in Lina Bo Bardi and Carlo Pagani's 'Casa sul Mare di Sicilia' – a theoretical project by Lina Bo Bardi designed for Domus in 1940. It places particular emphasis on Bo Bardi's essay entitled "Architecture and Nature: The House in the Landscape" (1943), where she expresses her admiration for the typology of the Mediterranean house: "The world is full of examples of the perfect correspondence between this architecture and the environment in which human lives unfold, but none is so succinct as the Mediterranean house, none so pure and perfectly integrated into the earth and the landscape, so consonant with the life going on within and around it". These characteristics of the Mediterranean house are very present in the 'Casa sul Mare di Sicilia'. Bo Bardi and Pagani aimed to integrate the house into the landscape and the cultural context of Sicily, which is characterised by the strong presence of the mythology of Magna Graecia. Among the core characteristics of the 'Casa sul Mare di Sicilia' are its patio, its Mediterranean atmosphere, its respect for the natural and cultural context, the interest in vernacular anonymous architecture, and its use of the symbolic and archetypal features of mythological figures, such as Ulysses and his dog, and Hermes of Zeus's "Askraios" in its drawings. The paper examines how Bo Bardi and Pagani related the integration of the Mediterranean house in the landscape to the concept of Magna Graecia, and how they turn the landscape into the very device that connects architecture to the myth of the archetype in the Mediterranean vernacular. At the centre of the reflections developed in the paper is their conviction that "architecture must be the key to the landscape", transforming into the landscape, and becoming landscape itself.
Finding connections between fundamentally different conceptions of “models”
Creators: name: Bradley, John
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Texts
subject: Big data
subject: Information visualization

description: One of the major projects in the DH has been to find meanings in text through digital means—text analysis—and the recent the emergence of Large Language Models has presented a radically new extension to this. In contrast, almost all my professional DH life at KCL (in 25 substantial funded DH projects) has centered not on text analysis but representation through highly structured data (usually in terms of the relational database). Also, my Pliny project has explored how aspects of the more informal process of humanities research which is, at least in good part, about finding new interpretations could be usefully supported digitally. Both Pliny and most of the highly structured projects have text "nestled" within them.   Both highly structured data and LLMs create models expressing some the semantics of their material, but LLM’s models are very different kind of thing from models represented by graph-oriented highly structured data projects (and in Pliny). Is there any point of connection? To explore this issue we have built mechanisms to extract the textual bits from Record of Early English Drama’s (U of Toronto) EMLoT resource, and from the Pliny dataset of a significant Pliny user. Text analysis techniques have then been applied to uncover structure. We have begun this work with Voyant, and continued by applying basic LLM models and examined how these language Models might characterize these texts.  Text operating semantically can be found in highly structured data, and particularly in Pliny. Hence, part of the semantic significance of these projects is not found only in their object structure, but also in the text in these structures, and the semantic meaning between the text and the data structure is likely to be complementary. This poster reveals some initial ways in which points of contact can be found in these data structure and text visualizations. Do they enable a fuller vision of what our materials represent than either do by themselves?
Finding connections between fundamentally different conceptions of "models"
Creators: name: Bradley, John
Publisher: name: unknown
Year: 2024
Subjects: subject: Information visualization
subject: Big data
subject: Texts

description: One of the major projects in the DH has been to find meanings in text through digital means—text analysis—and the recent the emergence of Large Language Models has presented a radically new extension to this. In contrast, almost all my professional DH life at KCL (in 25 substantial funded DH projects) has centered not on text analysis but representation through highly structured data (usually in terms of the relational database). Also, my Pliny project has explored how aspects of the more informal process of humanities research which is, at least in good part, about finding new interpretations could be usefully supported digitally. Both Pliny and most of the highly structured projects have text "nestled" within them.

Both highly structured data and LLMs create models expressing some the semantics of their material, but LLM's models are very different kind of thing from models represented by graph-oriented highly structured data projects (and in Pliny). Is there any point of connection? To explore this issue we have built mechanisms to extract the textual bits from Record of Early English Drama's (U of Toronto) EMLoT resource, and from the Pliny dataset of a significant Pliny user. Text analysis techniques have then been applied to uncover structure. We have begun this work with Voyant, and continued by applying basic LLM models and examined how these language Models might characterize these texts.

Text operating semantically can be found in highly structured data, and particularly in Pliny. Hence, part of the semantic significance of these projects is not found only in their object structure, but also in the text in these structures, and the semantic meaning between the text and the data structure is likely to be complementary. This poster reveals some initial ways in which points of contact can be found in these data structure and text visualizations. Do they enable a fuller vision of what our materials represent than either do by themselves?
Table_S1._Strains_and_plasmids_used_in_this_study from The outer membrane phospholipase A is essential for membrane integrity and type III secretion in Shigella flexneri
Creators: name: Wang, Xia
name: Jiang, Feng
name: Jianhua Zheng
name: Lihong Chen
name: Dong, Jie
name: Sun, Lilian
name: Yafang Zhu
name: Liu, Bo
name: Yang, Jian
name: Guowei Yang
name: Jin, Qi
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Outer membrane phospholipase A (OMPLA) is an enzyme located in the outer membrane of Gram-negative bacteria. OMPLA exhibits broad substrate specificity, and some of its substrates are located in the cellular envelope. Generally, the enzymatic activity can only be induced by perturbation of the cell envelope integrity through diverse methods. Although OMPLA has been thoroughly studied as a membrane protein in Escherichia coli and is constitutively expressed in many other bacterial pathogens, little is known regarding the functions of OMPLA during the process of bacterial infection. In this study, the proteomic and transcriptomic data indicated that OMPLA in Shigella flexneri, termed PldA, both stabilizes the bacterial membrane and is involved in bacterial infection under ordinary culture conditions. A series of physiological assays substantiated the disorganization of the bacterial outer membrane and the periplasmic space in the ΔpldA mutant strain. Furthermore, the ΔpldA mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. The results of this study support PldA, which is widespread across Gram-negative bacteria, as an important factor for the bacterial life cycle, particularly in human pathogens.
E-Commerce
Creators: name: Williams, Dana
Publisher: name: Blackwell
Year: 2024
Subjects: subject: Consumption (Economics)
subject: Internet
subject: Retail trade
subject: Commerce
subject: Economics
subject: Mobile commerce
subject: Consumers

description: Electronic commerce (e-commerce) involves business that is done electronically and includes economic exchange between businesses (B2B), businesses selling to consumers (B2C), or exchange between individual consumers (C2C). By the twenty-first century, e-commerce had become increasingly central to affluent economies, as a result of the creation of vast telecommunications networks and the Internet; the proliferation of personal computers and mobile phones; developments in business systems, software, and websites; and the establishment of trust in vendor reliability and personal financial information security (especially credit cards), through promotional marketing and advances in encryption.
The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models.
Creators: name: Lee, Juliette J
name: Andreazza, Simonetta
name: Whitworth, Alexander J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Mutations in PINK1 and Parkin/PRKN cause the degeneration of dopaminergic neurons in familial forms of Parkinson's disease but the precise pathogenic mechanisms are unknown. The PINK1/Parkin pathway has been described to play a central role in mitochondrial homeostasis by signalling the targeted destruction of damaged mitochondria, however, how disrupting this process leads to neuronal death was unclear until recently. An elegant study in mice revealed that the loss of Pink1 or Prkn coupled with an additional mitochondrial stress resulted in the aberrant activation of the innate immune signalling, mediated via the cGAS/STING pathway, causing degeneration of dopaminergic neurons and motor impairment. Genetic knockout of Sting was sufficient to completely prevent neurodegeneration and accompanying motor deficits. To determine whether Sting plays a conserved role in Pink1/parkin related pathology, we tested for genetic interactions between Sting and Pink1/parkin in Drosophila. Surprisingly, we found that loss of Sting, or its downstream effector Relish, was insufficient to suppress the behavioural deficits or mitochondria disruption in the Pink1/parkin mutants. Thus, we conclude that phenotypes associated with loss of Pink1/parkin are not universally due to aberrant activation of the STING pathway.
IMPORTANCE-PERFORMANCE ANALYSIS OF A RESTAURANT MOBILE BOOKING AND RESERVATION APPLICATION
Creators: name: Buenaventura, John Paul G.
name: Clemente, Franz Joseph I.
name: Diño, Gail Bien Aubrey S.
name: Diño, Gail Bien Aubrey S.
name: Gonzales, Nelson Jr. S.
name: Rodilas, Raven Jewell
name: Rojas, Michelle T.
Publisher: name: Humanities Commons
Year: 2024

description: This study examined issues with performance and ongoing user dissatisfaction in the OpenTable application, a well-known restaurant booking and reservation platform in the Philippines. Researchers use the Importance-Performance Analysis (IPA) model to assess OpenTable's importance and performance. Researchers also use Gummesson's 4Q-Quality Model to improve the analysis structure. Researchers gathered comprehensive data by distributing a structured survey questionnaire to 120 individuals who use OpenTable. Ethical considerations guide researchers' investigation at every step. The researchers showed their commitment to methodological and ethical standards by thoroughly outlining the research's design, sampling approach, data gathering methods, and interpretation approaches. A Likert scale was used in the survey questionnaire for performance analysis and importance assessment, and it has been validated through a methodical approach, the findings revealed that: The most significant discrepancy between performance and importance can be observed in the product and service quality (0.70), followed by Designed Quality, Relational Quality (0.59), and Outcome Quality (0.56). For the greatest influence on consumer/users’ satisfaction, this proposes putting efforts to make improvements in product and service quality, relational quality, and designed quality. OpenTable is recommended to focus on enhancing communication channels, brand identity, and user experience. Management should place a high priority on resource allocation and transparent communication, and feedback is encouraged. It's recommended that features like responsive reservation updates and live chat assistance be included.
#DHmakes: Baking Craft into DH Discourse
Creators: name: Berger, Claudia
name: Dombrowski, Quinn
name: Wyatt Visconti, Amanda
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Digital humanities
subject: Makerspaces
subject: Makerspaces in libraries
subject: Fabric arts
subject: Information visualization
subject: Social media

description: This paper traces the history and development of the collaborative #DHmakes initiative to bring crafts into the mainstream of Anglophone digital humanities, starting in 2022 but building upon earlier calls to bridge the maker / craft divide. It argues for the importance of this work within digital humanities as a way of reconnecting technology with its textile roots, while also recognizing the creative and intellectual potential found in feminine-coded craft praxis. The history of different phases within digital humanities is often poorly documented. By recording the development of this recent movement – already a challenge following a mass exodus from Twitter, where much of these conversations initially took place – this paper captures the origins of an important moment in the field, as “digital humanities” was coming to understand itself more capaciously than the “digital” alone would imply.
Machine Learning in Edge Computing: Opportunities and Challenges
Creators: name: Krishnamoorthy, Gowrisankar
name: Kumar Konidena, Bhargav
name: Pakalapati, Naveen
name: Pakalapati, Naveen
Publisher: name: Humanities Commons
Year: 2024

description: The integration of machine learning in edge computing has emerged as a transformative paradigm, offering unprecedented opportunities and challenges. This review paper explores the consequences for network architecture, privacy, security, and resource efficiency while also delving into the dynamic environment of this convergence. The article guides the reader through the developments in artificial intelligence (AI) in edge computing settings using current research findings. This article covers important topics such as energy use optimization and data processing efficiency, summarizing important discoveries and offering a comprehensive overview of the state of machine learning in edge computing. A thorough analysis of AI methods, compute offloading techniques, and security precautions clarifies the way forward for utilizing edge computing and machine learning in the future.
Machine Learning for Demand Forecasting in Manufacturing
Creators: name: Jeyaraman, Jawaharbabu
name: Krishnamoorthy, Gowrisankar
name: Kumar Konidena, Bhargav
name: Kumar Konidena, Bhargav
name: Sistla, Sai Mani Krishna
Publisher: name: Humanities Commons
Year: 2024

description: This research paper investigates the application of machine learning (ML) techniques in demand forecasting within the manufacturing sector. By analyzing case studies, practical examples, and comparative studies, we explore the effectiveness and challenges of ML-driven demand forecasting. The paper discusses various ML techniques, including regression models, time series forecasting methods, neural networks, and ensemble methods, highlighting their strengths and limitations. Evaluation metrics such as Mean Absolute Error (MAE), Root Mean Squared Error (RMSE), and Mean Absolute Percentage Error (MAPE) are examined to assess forecasting accuracy. Additionally, challenges such as data quality, model interpretability, computational resources, and overfitting are discussed, along with recommendations for addressing these challenges. The paper concludes with recommendations for practitioners and suggestions for future research directions, emphasizing the importance of data quality improvement, model interpretability enhancement, and ethical considerations in ML-based demand forecasting
Supplemental figures 1-3 from The outer membrane phospholipase A is essential for membrane integrity and type III secretion in Shigella flexneri
Creators: name: Wang, Xia
name: Jiang, Feng
name: Jianhua Zheng
name: Lihong Chen
name: Dong, Jie
name: Sun, Lilian
name: Yafang Zhu
name: Liu, Bo
name: Yang, Jian
name: Guowei Yang
name: Jin, Qi
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Outer membrane phospholipase A (OMPLA) is an enzyme located in the outer membrane of Gram-negative bacteria. OMPLA exhibits broad substrate specificity, and some of its substrates are located in the cellular envelope. Generally, the enzymatic activity can only be induced by perturbation of the cell envelope integrity through diverse methods. Although OMPLA has been thoroughly studied as a membrane protein in Escherichia coli and is constitutively expressed in many other bacterial pathogens, little is known regarding the functions of OMPLA during the process of bacterial infection. In this study, the proteomic and transcriptomic data indicated that OMPLA in Shigella flexneri, termed PldA, both stabilizes the bacterial membrane and is involved in bacterial infection under ordinary culture conditions. A series of physiological assays substantiated the disorganization of the bacterial outer membrane and the periplasmic space in the ΔpldA mutant strain. Furthermore, the ΔpldA mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. The results of this study support PldA, which is widespread across Gram-negative bacteria, as an important factor for the bacterial life cycle, particularly in human pathogens.
Perovskite-molecule composite thin films for efficient and stable light-emitting diodes.
Creators: name: Wang, Heyong
name: Kosasih, Felix Utama
name: Yu, Hongling
name: Zheng, Guanhaojie
name: Zhang, Jiangbin
name: Pozina, Galia
name: Liu, Yang
name: Bao, Chunxiong
name: Hu, Zhangjun
name: Liu, Xianjie
name: Kobera, Libor
name: Abbrent, Sabina
name: Brus, Jiri
name: Jin, Yizheng
name: Fahlman, Mats
name: Friend, Richard H
name: Ducati, Caterina
name: Liu, Xiao-Ke
name: Gao, Feng
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Although perovskite light-emitting diodes (PeLEDs) have recently experienced significant progress, there are only scattered reports of PeLEDs with both high efficiency and long operational stability, calling for additional strategies to address this challenge. Here, we develop perovskite-molecule composite thin films for efficient and stable PeLEDs. The perovskite-molecule composite thin films consist of in-situ formed high-quality perovskite nanocrystals embedded in the electron-transport molecular matrix, which controls nucleation process of perovskites, leading to PeLEDs with a peak external quantum efficiency of 17.3% and half-lifetime of approximately 100 h. In addition, we find that the device degradation mechanism at high driving voltages is different from that at low driving voltages. This work provides an effective strategy and deep understanding for achieving efficient and stable PeLEDs from both material and device perspectives.
From Theory to Practice: Implementing AI Technologies in Project Management
Creators: name: Karamthulla, Musarath Jahan
name: Malaiyappan, Jesu Narkarunai Arasu
name: Muthusubramanian, Muthukrishnan
name: Muthusubramanian, Muthukrishnan
name: Tillu, Ravish
Publisher: name: Humanities Commons
Year: 2024

description: This research paper explores the integration of Artificial Intelligence (AI) technologies in project management, analysing current trends, challenges, and practical examples. The paper investigates the benefits of AI in streamlining project workflows, enhancing decision-making processes, and mitigating risks. Through case studies and emerging trends, it identifies key recommendations for successful AI implementation, including prioritizing data quality, promoting ethical AI practices, fostering a culture of innovation, embracing collaborative approaches, and monitoring performance. By adhering to these recommendations, organizations can harness the transformative potential of AI to improve project outcomes and achieve strategic objectives in an increasingly digital and competitive landscape
Single-photon emission from single-electron transport in a SAW-driven lateral light-emitting diode.
Creators: name: Hsiao, Tzu-Kan
name: Rubino, Antonio
name: Chung, Yousun
name: Son, Seok-Kyun
name: Hou, Hangtian
name: Pedrós, Jorge
name: Nasir, Ateeq
name: Éthier-Majcher, Gabriel
name: Stanley, Megan J
name: Phillips, Richard T
name: Mitchell, Thomas A
name: Griffiths, Jonathan P
name: Farrer, Ian
name: Ritchie, David A
name: Ford, Christopher J B
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: The long-distance quantum transfer between electron-spin qubits in semiconductors is important for realising large-scale quantum computing circuits. Electron-spin to photon-polarisation conversion is a promising technology for achieving free-space or fibre-coupled quantum transfer. In this work, using only regular lithography techniques on a conventional 15 nm GaAs quantum well, we demonstrate acoustically-driven generation of single photons from single electrons, without the need for a self-assembled quantum dot. In this device, a single electron is carried in a potential minimum of a surface acoustic wave (SAW) and is transported to a region of holes to form an exciton. The exciton then decays and creates a single optical photon within 100 ps. This SAW-driven electroluminescence, without optimisation, yields photon antibunching with g(2)(0) = 0.39 ± 0.05 in the single-electron limit (g(2)(0) = 0.63 ± 0.03 in the raw histogram). Our work marks the first step towards electron-to-photon (spin-to-polarisation) qubit conversion for scaleable quantum computing architectures.
Advancements in Reinforcement Learning Algorithms for Autonomous Systems
Creators: name: Jeyaraman, Jawaharbabu
name: Malaiyappan, Jesu Narkarunai Arasu
name: Malaiyappan, Jesu Narkarunai Arasu
name: Sistla, Sai Mani Krishna
Publisher: name: Humanities Commons
Year: 2024

description: Reinforcement learning, often known as RL, has developed as a strong paradigm to teach autonomous software agents to make choices in contexts that are both complicated and dynamic. This abstract investigates recent developments and uses of RL in a variety of fields, showing both its transformational potential and the constraints that it faces at present. Recent developments in reinforcement learning (RL) algorithms, in particular deep reinforcement learning (DRL), have made it possible to make major advancements in autonomous decisionmaking tasks. DRL algorithms can learn complicated representations of state-action spaces by using deep neural networks. This allows for more efficient exploration and exploitation methods to be implemented. Additionally, advancements in algorithmic enhancements, such as prioritized experience replay and distributional reinforcement learning, have improved the stability and sample efficiency of reinforcement learning algorithms, which has made it possible for these algorithms to be used in real-world applications. Robotics, autonomous cars, game playing, finance, and healthcare are just a few of the many fields that may benefit from the use of RL. In the field of robotics, reinforcement learning (RL) makes it possible for autonomous agents to learn how to navigate, manipulate, and move about in environments that are both complicated and unstructured. To improve both safety and efficiency on the road, autonomous cars make use of reinforcement learning (RL) to make decisions in dynamic traffic situations. In finance, RL algorithms are used for portfolio optimization, algorithmic trading, and risk management. These applications serve to improve investment techniques and decision-making procedures. Furthermore, in the field of healthcare, RL supports individualized treatment planning, clinical decision support, and medical image analysis, which enables physicians to provide patients with care that is specifically suited to their needs.
Mutational signatures: experimental design and analytical framework.
Creators: name: Koh, Gene
name: Zou, Xueqing
name: Nik-Zainal, Serena
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: Mutational signatures provide a powerful alternative for understanding the pathophysiology of cancer. Currently, experimental efforts aimed at validating and understanding the etiologies of cancer-derived mutational signatures are underway. In this review, we highlight key aspects of mutational signature experimental design and describe the analytical framework. We suggest guidelines and quality control measures for handling whole-genome sequencing data for mutational signature analyses and discuss pitfalls in interpretation. We envision that improved next-generation sequencing technologies and molecular cell biology approaches will usher in the next generation of studies into the etiologies and mechanisms of mutational patterns uncovered in cancers.
The Long Road to Map Discovery: Two Multi-institutional Projects
Creators: name: Weessies, Kathleen
name: Wilson, Kasey Reed
Publisher: name: Humanities Commons
Year: 2016
Subjects: subject: Geospatial data
subject: Maps
subject: Metadata

description: Detailed topographic maps sets are of great value for scholarly work from the humanities to the sciences.  Library catalogs, however, are poorly designed to communicate holdings down to the sheet level to library users.  Two multi-institutional projects have the goal of providing greater access to topographic map sets, antique maps, and geospatial data.  One is the GIS-based Discovery to Paper Map Sets Project begun by Chris Thiry at the Colorado School of Mines.  The second is the CIC Geospatial Data Discovery Project jointly funded by several large universities in the US Midwest.  The paper briefly describes the goals and process of each project but focuses on the practical matters of participation including time and resource investment, perceived benefits, and technical and procedural challenges.
'Libertà et licenza... di stampare mille heræsie et schismi:' The Propaganda Fide and the Greek Printing Press at Constantinople (1627–1628)
Creators: name: - Victor Olar, Ovidiu
Publisher: name: De Gruyter
Year: 2024

description: The opening of the first Greek press in the Ottoman Empire generated great interest among scholars. Valuable studies have been dedicated to its founder (Nikodimos Metaxas), its patron (Kyrillos Loukaris), its supporters, and its adversaries. Despite the sustained interest, however, historians still struggle to untangle the complicated web of truths, half-truths, lies, and deceit surrounding the failed "adventure." Since Propaganda Fide was one of the major actors interested in the event, deconstructing its aggressive attitude towards Loukaris and the first Greek printing press of Constantinople sheds additional light on this dark but spectacular corner of early modern European confessional history. Corroborating Francesco Ingoli's "Report on the Four Parts of the World" (Relazione delle Quattro Parti del Mondo) with archival materials, I argue that the founding of a Greek printing press at Constantinople, in the summer of 1627, played a major role in shaping Propaganda's policies with regards to Loukaris.
title: Parents d'enfant hémiparésique : Points de vue sur les obstacles et les facilitateurs à la participation sociale de leur enfant, dans un contexte scolaire ordinaire, en Suisse romande
title: Parents d'enfant hémiparésique : Points de vue sur les obstacles et les facilitateurs à la participation sociale de leur enfant, dans un contexte scolaire ordinaire, en Suisse romande
titleType: AlternativeTitle
Creators: name: Leyvraz, Justine
name: Schwarz, Sylvie
Publisher: name: Unknown
Year: 0
Subjects: subject: Hémiparésie
subject: inclusion scolaire
subject: participation sociale
subject: point de vue des parents
subject: advocacy

description: L’hémiparésie est une forme de paralysie cérébrale, résultant d’un accident vasculaire cérébral, qui touche plusieurs enfants chaque année en Suisse romande. Avec l’école inclusive et le concept 360, la majorité de ces enfants, du moins dans les premiers degrés, sont scolarisés dans l’école ordinaire. La littérature scientifique a mis en évidence que les enfants en situation de handicap sont plus isolés socialement que leurs pairs valides. Notre recherche s’est penchée sur la participation sociale de ces enfants en milieu scolaire ordinaire. Nous avons adopté la perspective d’un modèle intégratif du handicap, qui prend en compte dans son analyse les facteurs personnels et les facteurs environnementaux. Le but de notre recherche a été d’identifier, dans l’environnement, les obstacles et les facilitateurs à la participation sociale dans le contexte scolaire ordinaire. L’enquête mise en place s’inscrit dans une perspective qualitative phénoménologique, et vise à rendre compte de l’expérience des parents interrogés concernant la participation sociale de leur enfant. Les résultats ont démontré que la participation sociale n’est pas pleinement réalisée, et de nombreux éléments facilitateurs ou faisant obstacles à la participation sociale ont pu être mis en évidence. Ceux-ci ont pu être regroupés en différentes catégories : cadre de vie et réseau des proches, implication des parents dans le suivi scolaire et leur rôle d’expert, la collaboration école-famille, la structure et le fonctionnement du réseau qui entoure l’enfant ainsi que l’attitude inclusive de l’enseignant. Ces éléments constituent les principaux facteurs sur lesquels il serait possible d’influer pour améliorer la participation sociale des enfants hémiparésiques.
Supporting Dataset S3 from Onychophoran-like musculature in a phosphatized Cambrian lobopodian
Creators: name: Zhang, Xi-Guang
name: Smith, Martin R.
name: Yang, Jie
name: Hou, Jin-Bo
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The restricted, exclusively terrestrial distribution of modern Onychophora contrasts strikingly with the rich diversity of onychophoran-like fossils preserved in marine Cambrian Lagerstätten. The transition from these early forebears to the modern onychophoran body plan is poorly constrained, in part, owing to the absence of fossils preserving details of the soft anatomy. Here, we report muscle tissue in a new Early Cambrian (stage 3) lobopodian, Tritonychus phanerosarkus gen. et sp. nov., preserved in the Orsten fashion by three-dimensional replication in phosphate. This first report of Palaeozoic onychophoran musculature establishes peripheral musculature as a characteristic of the ancestral panarthropod, but documents an unexpected muscular configuration. Phylogenetic analysis reconstructs T. phanerosarkus as one of a few members of the main onychophoran lineage—which was as rare and as cryptic in the Cambrian period as it is today.
Les gravures des livres imprimés au XVIIIe siècle  au Monastère-Saint-Jean-Baptiste à Khenchara – Mont Liban
Creators: name: Nassif, Charbel
Publisher: name: Humanities Commons
Year: 2024

description: Abstract: This article aims to present  the books of the printing press founded by the Aleppian ʿAbd Allāh Zāḫir (1684-1748) at the Saint John the Baptist Monastery in Khenchara (Mount Lebanon) in the 18th century, the motherhouse of the Choueirite Basilian Order. The Khenchara printing press stands out as one of the most important in the 18th century in the Middle East, playing a crucial role in the spread of Catholicism while making a significant contribution to the enrichment of the Melkite Greek Church through the printing of liturgical works. Its artistic heritage is remarkable, blending iconographic motifs from the Byzantine tradition with Western motifs, thus illustrating the cultural and religious diversity that characterizes the Melkite environment.  Keywords: Printing; Engravings; Catholicism; Byzantine liturgy; Western motifs; Melkite Church.
A Comparison of Conventional Outpatient and Instrumental Intraoperative POP-Q Measurements in Patients Undergoing Vaginal Surgery for Pelvic Organ Prolapse
Creators: name: Kreaingsak Sirisakpanich
Publisher: name: PIMDEE Co., Ltd.
Year: 2024
Subjects: pelvic organ prolapse
POP-Q examination
POP-Q measurement
outpatient
intraoperative

description: Thai Journal of Obstetrics and Gynaecology, 32, 4, 261-268
Accuracy of the Combined First Trimester Down Syndrome Screening Test and the Optimum Range of the Cut-off Point for Intermediate-risk Identification: Twelve years' experience
Creators: name: Thanapa Rekhawasin Pinnington
Publisher: name: PIMDEE Co., Ltd.
Year: 2024
Subjects: combined first-trimester
cut-off point
Down syndrome
intermediate risk
screening

description: Thai Journal of Obstetrics and Gynaecology, 32, 4, 269-277
Comparing the Different Antenatal Nutritional Counseling Methods Regarding Proper Gestational Weight Gain during the Second Trimester: A randomized, controlled trial
Creators: name: Sukanya Sareerat
Publisher: name: PIMDEE Co., Ltd.
Year: 2024
Subjects: weight gain
nutrition
counseling
computer-assisted instruction

description: Thai Journal of Obstetrics and Gynaecology, 32, 4, 278-286
Giulio Mancinelli, SJ (†1618) and his Journey across Wallachia and Moldavia
Creators: name: - Victor Olar, Ovidiu
Publisher: name: Brill | Schöningh
Year: 2024

description: In the late summer of 1585, the superior of the first Jesuit mission to Constantinople, Giulio Mancinelli SI, abandoned his post, embarked on a merchant ship, and headed towards Poland. The adventure did not last long, but figured in Mancinelli's autobiography, written and re-written from 1602 on. Many scholars mined this self-narrative for information. Yet the text as a whole remained elusive and the official biography, issued fifty years after its subject's death, in an attempt to push for his canonization, is even more puzzling. The aim of the present paper is to examine documents held in the Roman Archives of the Society of Jesus and read both self-narratives and hagiography against them. Based on archival materials and recent studies on the Early Modern Jesuit missions to Eastern Christian communities, I argue that Mancinelli's brief journey across Moldavia sheds light on the beginnings of Catholic missionary activity in Ottoman Europe, as well as on Early Modern (Jesuit) autobiographical writing and self-fashioning.
Paragraph Mapping: A Strategy for Teaching Close Reading & Analysis Skills
Creators: name: Stecher, Gabrielle
Publisher: name: unknown
Year: 2024
Subjects: subject: Literacy
subject: Teaching
subject: Writing
subject: Literary criticism
subject: Reading comprehension
subject: Education

description: In order to effectively analyze the entirety of a rigorous text, whether it be a primary or secondary source, students need to hone their comprehension and analysis skills. This activity empowers students to practice their close reading skills by unpacking one part of a larger whole. Paragraph mapping is a visual close reading strategy that begins when students select one particularly rich or dense paragraph or passage from an assigned text. They start by identifying, researching, and defining four key vocabulary words. Then, they research the context of the text's authorship before summarizing, analyzing, and reflecting on the passage.
Table S6. The genus with co-occurrence of PldA and T3SS in the phylogenetic tree from The outer membrane phospholipase A is essential for membrane integrity and type III secretion in Shigella flexneri
Creators: name: Wang, Xia
name: Jiang, Feng
name: Jianhua Zheng
name: Lihong Chen
name: Dong, Jie
name: Sun, Lilian
name: Yafang Zhu
name: Liu, Bo
name: Yang, Jian
name: Guowei Yang
name: Jin, Qi
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Outer membrane phospholipase A (OMPLA) is an enzyme located in the outer membrane of Gram-negative bacteria. OMPLA exhibits broad substrate specificity, and some of its substrates are located in the cellular envelope. Generally, the enzymatic activity can only be induced by perturbation of the cell envelope integrity through diverse methods. Although OMPLA has been thoroughly studied as a membrane protein in Escherichia coli and is constitutively expressed in many other bacterial pathogens, little is known regarding the functions of OMPLA during the process of bacterial infection. In this study, the proteomic and transcriptomic data indicated that OMPLA in Shigella flexneri, termed PldA, both stabilizes the bacterial membrane and is involved in bacterial infection under ordinary culture conditions. A series of physiological assays substantiated the disorganization of the bacterial outer membrane and the periplasmic space in the ΔpldA mutant strain. Furthermore, the ΔpldA mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. The results of this study support PldA, which is widespread across Gram-negative bacteria, as an important factor for the bacterial life cycle, particularly in human pathogens.
Paragraph Mapping: A Strategy for Teaching Close Reading & Analysis Skills
Creators: name: Stecher, Gabrielle
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: Reading comprehension
subject: Literary criticism
subject: Writing
subject: Literacy
subject: Teaching
subject: Education

description: In order to effectively analyze the entirety of a rigorous text, whether it be a primary or secondary source, students need to hone their comprehension and analysis skills. This activity empowers students to practice their close reading skills by unpacking one part of a larger whole. Paragraph mapping is a visual close reading strategy that begins when students select one particularly rich or dense paragraph or passage from an assigned text. They start by identifying, researching, and defining four key vocabulary words. Then, they research the context of the text’s authorship before summarizing, analyzing, and reflecting on the passage.
ESM Supplementary Legends Figures and Table from A model for the effects of germanium on silica biomineralization in choanoflagellates
Creators: name: Marron, Alan O.
name: Chappell, Helen
name: Ratcliffe, Sarah
name: Goldstein, Raymond E.
Publisher: name: The Royal Society
Year: 2016
Subjects: subject: Biochemistry
subject: 90301 Biomaterials
subject: FOS: Medical engineering

description: Silica biomineralization is a widespread phenomenon of major biotechnological interest. Modifying biosilica with substances like germanium (Ge) can confer useful new properties, although exposure to high levels of Ge disrupts normal biosilicification. No clear mechanism explains why this disruption occurs. Here we study the effect of Ge on loricate choanoflagellates, a group of protists that construct a species-specific extracellular lorica from multiple siliceous costal strips. High Ge exposures were toxic, whereas lower Ge exposures produced cells with incomplete or absent loricae. These effects can be ameliorated by restoring the Germanium : Silicon ratio, as observed in other biosilicifying organisms. We developed simulations of how Ge interacts with polymerizing silica. In our models, Ge is readily incorporated at the ends of silica forming from silicic acid condensation, but this prevents further silica polymerization. Our ‘Ge-capping’ model is supported by observations from loricate choanoflagellates. Ge exposure terminates costal strip synthesis and lorica formation, resulting in disruption to cytokinesis and fatal build-up of silicic acid. Applying the Ge-capping model to other siliceous organisms explains the general toxicity of Ge and identifies potential protective responses in metalloid uptake and sensing. This can improve the design of new silica biomaterials, and further our understanding of silicon metabolism.
Research Capability of Doctoral Students in Utilizing Multivariate Statistics, Writing Research Proposal and Publishable Paper
Creators: name: Caingcoy, Manuel
Publisher: name: Humanities Commons
Year: 2024

description: Advanced studies aim to produce highly competent graduates in areas like research and publication. These expectations necessitate research capabilities in graduate students. To assess doctoral students' research abilities and inform instruction, a research course evaluates them at the beginning of the term. Employing a descriptive design, this study investigated 21 individuals enrolled in an advanced research course during the second term of the academic year 2022-2023. Data were collected using an adapted instrument. The results indicated that doctoral students possessed moderate capabilities in writing a research proposal. However, they reported feeling neutral regarding their ability to write publishable papers. Additionally, these individuals indicated a slight or limited capability for utilizing multivariate statistics. These findings hold implications for instruction and future research, particularly in prioritizing course content to address areas where doctoral students have limited research capabilities.
Comparison of the Efficacy between Conjugated Equine Estrogen versus Nonsteroidal Anti-inflammatory Drug for the Cessation of Uterine Bleeding among Contraceptive Implant Users: A randomized controlled trial
Creators: name: Salinee Polyota
Publisher: name: PIMDEE Co., Ltd.
Year: 2024
Subjects: abnormal uterine bleeding
hormonal subdermal implant
conjugated equine estrogen
mefenamic acid

description: Thai Journal of Obstetrics and Gynaecology, 32, 4, 287-294
Prevalence of Depressive Symptoms among Thai Reproductive-Aged Woman with Polycystic Ovary Syndrome and Associated Factors
Creators: name: Thanaree Achavangkool
Publisher: name: PIMDEE Co., Ltd.
Year: 2024
Subjects: depression
PCOS
PHQ-9

description: Thai Journal of Obstetrics and Gynaecology, 32, 4, 295-305