cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ol'ga Slivickaja, Un ‘incontro ideale’: Lermontov e Tolstoj
Creators: name: Illarionova, Elizaveta
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: Il saggio indaga l’antropologia culturale in Un eroe del nostro tempo di Lermontov a confronto con i romanzi di Tolstoj. L’analisi della novella Maksim Maksimyč permette di scoprire nella contrapposizione di Pečorin e Maksim Maksimyč il tema del conflitto culturale tra un uomo eccezionale e un «uomo semplice» e, in una visione più ampia, tra l’intelligencija e il popolo. Tale conflitto, irrisolto nel romanzo di Lermontov ad eccezione del tema del fatalismo comune a tutti i personaggi, verrà sanato nella figura di Pierre Bezuchov di Guerra e pace. In conclusione, si riafferma il duplice ruolo di Lermontov come antesignano di Tolstoj ma anche artista autonomo dalle scelte artistiche non inferiori ma radicalmente diverse da quelle tolstoiane.
description: ENTHYMEMA, N° 4 (2011)
title: Mass occurrence of anatoxin-a- and dihydroanatoxin-a-producing tychonema sp. in mesotrophic reservoir mandichosee (River Lech, Germany) as a cause of neurotoxicosis in dogs
title: Mass occurrence of anatoxin-a- and dihydroanatoxin-a-producing tychonema sp. in mesotrophic reservoir mandichosee (River Lech, Germany) as a cause of neurotoxicosis in dogs
titleType: AlternativeTitle
Creators: name: Bauer, Franziska
name: Fastner, Jutta
name: Bartha-Dima, Bernadett
Publisher: name: My University
Year: 2020
Subjects: Blaualgen
Makrophyten
Benthal
Wasserspeicher

description: In August 2019, three dogs died after bathing in or drinking from Mandichosee, a mesotrophic reservoir of the River Lech (Germany). The dogs showed symptoms of neurotoxic poisoning and intoxication with cyanotoxins was considered. Surface blooms were not visible at the time of the incidents. Benthic Tychonema sp., a potential anatoxin-a (ATX)-producing cyanobacterium, was detected in mats growing on the banks, as biofilm on macrophytes and later as aggregations floating on the lake surface. The dogsâ€Ì pathological examinations showed lung and liver lesions. ATX and dihydroanatoxin-a (dhATX) were detected by LC-MS/MS in the stomachs of two dogs and reached concentrations of 563 and 1207 Ìg/L, respectively. Anatoxins (sum of ATX and dhATX, ATXs) concentrations in field samples from Mandichosee ranged from 0.1 Ìg/L in the open water to 68,000 Ìg/L in samples containing a large amount of mat material. Other (neuro)toxic substances were not found. A molecular approach was used to detect toxin genes by PCR and to reveal the cyanobacterial community composition by sequencing. Upstream of Mandichosee, random samples were taken from other Lech reservoirs, uncovering Tychonema and ATXs at several sampling sites. Similar recent findings emphasize the importance of focusing on the investigation of benthic toxic cyanobacteria and applying appropriate monitoring strategies in the future. © 2020 by the authors
External (bank) funding for SMEs: 'finance gap' versus 'pecking order theory'
Creators: name: Watson, John
Publisher: name: Swinburne
Year: 2024

description: Previous research suggests that a lack of external funding opportunities (referred to as a 'finance gap') might inhibit the growth of many small and medium enterprises (SMEs). Further, it has been suggested that banks might routinely discriminate against females causing the 'finance gap' to be more acute for female-controlled SMEs. Based on this concept of a 'finance gap' we would expect younger SMEs to have relatively less debt than older SMEs (other things being equal). By way of contrast, 'pecking order theory' suggests that SME owners will only consider external financing options where insufficient internal funds are available to take advantage of value adding opportunities. Based on 'pecking order theory', we would expect (other things being equal) younger firms to have relatively more debt than older SMEs (that have had time to generate internal funds). From the discussion above it can be seen that these two concepts ('finance gap' and 'pecking order theory') potentially lead to opposing conclusions with respect to the relative levels of external debt we might expect in younger versus older firms. It has also been suggested that, because females are more risk averse and have a higher need to be in control, 'pecking order theory' might apply more strongly to female- as opposed to male-controlled SMEs. However, the existing empirical research on the above issues is extremely limited. The aim of this study, therefore, was to gain a better understanding of the relationship between SME growth and external debt (bank) funding and, in particular, to determine if there are any significant differences between female- and male-controlled SMEs.
title: INVESTIGATION OF THE PERSONNEL ANXIETY AND PSYCHOLOGICAL NEEDS OF THE RETIRED PEOPLE WHO LIKE AND DON'T STAY IN THE HOUSE OF PEACE
title: Статья
titleType: Subtitle
Creators: name: YAVUZ, Mesut Cevdet
Publisher: name: "Южный Университет (ИУБиП)"
Year: 2020
Subjects: ANXIETY
HOPELESSNESS
PSYCHOLOGICAL NEEDS

Abstract
Sconfinamenti tra generi nella narrativa spagnola tra Otto e Novecento: alcuni esempi
Creators: name: Siviero, Donatella
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: La prefazione è un elemento paratestuale ricco di contraddizioni, paradossi e tranelli per il lettore. Un caso interessante è quello delle prefazioni che fanno parte integrante del gioco finzionale, come quelle anteposte alle false scritture autobiografiche, molto praticate nella Spagna tra Otto e Novecento. Qui l’autore lancia la sua sfida al lettore fingendo un’identità altra o mascherandosi e mettendo in pratica degli sconfinamenti tra generi. L’articolo propone l’analisi delle prefazioni autoriali e/o fittiziamente autoriali presenti in quattro opere narrative scritte tra la seconda metà dell’Ottocento e il Novecento (Mariquita y Antonio e Pepita Jiménez di Juan Valera, Jusep Torres Campalans di Max Aub e Quizá nos lleve el viento al infinito di Gonzalo Torrente Ballester), che si rivelano delle ingegnose, ambigue e complesse trappole argomentative.
description: ENTHYMEMA, N° 4 (2011)
D5.1 - Technical Integration Points and Testing Plan
Creators: name: UBITECH
Publisher: name: Zenodo
Year: 2020

description: In-detail documentation of the technical architecture for the ASCLEPIOS platform and the detailed integration points among the framework's mechanisms. Documentation of an integration plan to guide the integration of the mechanisms of the ASCLEPIOS platform. In-detail documentation of the testing and evaluation plan to verify the proper functioning and performance of the integrated ASCLEPIOS platform.
Farmers' markets: the small business counter-revolution in food production and retailing
Creators: name: Cameron, Alan
name: Guthrie, John
Publisher: name: Swinburne
Year: 2024

description: This paper explores the rationale for, and development of, farmers' markets in New Zealand. It examines the entrepreneurial demands required of farmers, growers and producers in order to succeed in a David and Goliath contest. The consumer needs met by farmers' markets are also explored. The research is viewed in the context of the dominance of globalised agribusiness in the food production and retailing process.
I cataloghi nella letteratura americana della Grande Depressione
Creators: name: Scarpino, Cinzia
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: Il presente saggio si propone di analizzare alcune opere letterarie in senso lato (poesie, libri-documentario, script di film-documetario) scritte negli Stati Uniti negli anni della Grande Depressione (1929-1941) alla luce della presenza ricorrente di cataloghi, liste e inventari. Partendo da un excursus storico circa la centralità del catalogo come forma narrativa atta a rendere l’abbondanza del Nuovo Mondo nella cultura e nella letteratura dell’Ottocento (dai diari dei primi esploratori agli scritti di Thomas Jefferson, dalle geremiadi puritane agli almanacchi e ai diari rurali, dalle teorizzazioni estetiche di Ralph Waldo Emerson al «poeta catalogatore» Walt Whitman e al Walden di H. D. Thoreau), il saggio si sofferma su alcune opere-documentario degli anni Trenta del Novecento; un periodo che, segnato profondamente dalla crisi economica e testimone di una riconfigurazione della geografia reale e simbolica del territorio nazionale, punta nuovamente a cataloghi e inventari, secondo una scelta retorica funzionale alla rappresentazione del rovescio del mito di abbondanza delle origini.
description: ENTHYMEMA, N° 4 (2011)
title: Economic opportunities of climate action
title: Wirtschaftliche Chancen durch Klimaschutz : Kurzbericht
titleType: AlternativeTitle
Creators: name: Kahlenborn, Walter
name: Oehlmann, Malte
name: Linsenmeier, Manuel
Publisher: name: My University
Year: 2019
Subjects: subject: Kohlendioxid
subject: Volkswirtschaft
subject: Klimaschutz
subject: Klimaänderung
subject: Paris Agreement
subject: CO2
subject: national economy
subject: climate protection
subject: climate change
subject: global greenhouse gas emission
subject: Climate | Energy
subject: Economy | Consumption

description: In 2015, the Paris Climate Agreement has created a new framework for fighting climate change. The world is set to become greenhouse gas-neutral by the middle of the 21st century. Global warming should be kept below two degrees Celsius or even limited to no more than 1.5 degrees Celsius. At the national level, all signatory countries are required to set binding goals and to take suitable action to reach them. In 2016 Germany adopted a long-term strategy in the form of the Climate Action Plan 2050. Against the backdrop of the Paris agreement Germany aims at greenhouse gas neutrality by 2050. The necessary international endeavours to reduce greenhouse gases lead to new export markets for climate-friendly goods and services. Climate change thus represents significant opportunities for the German economy. Along with additional export potentials, the German economy can profit from climate change in other ways: additional investments, extensive innovation effects, and lower costs through increasing efficiency. A comprehensive survey of the economic impacts of ambitious climate policy looks at these opportunities in detail. Three separate publications, summarized in this paper, intensively examine such important questions as: - What economic advantages has climate action already brought? - What future potentials result from the growing global market for goods for climate action? - What are the effects of an investment-oriented climate policy for the national economy? Quelle: Forschungsbericht
description: Climate protection pays off! This is the central statement of the study "Economic opportunities through climate protection". The study examined which economic effects climate protection policy has had so far and which potentials will arise in the future. The results show: Climate protection goes hand in hand with innovation. Together with the necessary investments in renewable energies, energy efficiency, building refurbishment and climate-friendly mobility, it makes Germany fit for the future. Wages and gross domestic product are also rising in a world where the climate is being protected.
Dal racconto allo stage: percorsi della memoria in Brian Friel
Creators: name: Cambria, Mariavita
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: Numerosi scrittori sono arrivati alla stesura di testi teatrali dopo aver sperimentato altri mezzi espressivi, che spesso hanno costituito una sorta di laboratorio artistico ed esperienziale di tematiche, metodi e strumenti. Tra questi, l’irlandese Brian Friel (1929-), che, dopo un’iniziale carriera come scrittore di racconti brevi, si è affermato sulla scena internazionale grazie ai suoi plays. Attraverso l’analisi di elementi di continuità tra Foundry House, un racconto breve del 1962, e il dramma Aristocrats (1979), questo contributo si propone di mettere in luce il fil rouge che lega i due testi costituito da una riflessione sui processi di memoria collettiva ed individuale che permea i lavori di Friel.
description: ENTHYMEMA, N° 4 (2011)
Musical Citizens: String Teachers' Perceptions of Citizenship Education in the Private Studio
Creators: name: Harrison, Joan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: benefits of music lessons
citizenship education
private music lessons
music education
democratic citizenship
studio instruction
string pedagogy
Suzuki music

description: This quantitative study explores string teachers’ perceptions of citizenship education and its use in the private lesson. Guided by Westheimer and Kahne’s (2004) model of citizenship education the study sought to identify (a) how private string teachers perceive citizenship education, and (b) the factors that influence these perceptions. Four hundred and fifteen (415) members of the American String Teachers Association (ASTA) participated in this study by completing an on-line survey that contained both closed and open-ended questions. The resulting data was coded and organized according to the survey questions and the conceptual framework. Research findings revealed that, although teachers did not explicitly consider citizenship education a part of their lessons, their intentions and their report on pedagogical practices could be described as citizenship education when viewed through the conceptual framework used in the study. Indeed, nearly all of the participant responses revealed intentions to include attributes of what Westheimer and Kahne refer to as the Personally Responsible Citizen in their music lessons with students. Educating for traits of other types of citizenship was also reported. Factors deemed influential in string teachers’ perceptions of citizenship education included the following: If the teachers had earned certification in Suzuki pedagogy; the number of years of teaching experience; if teachers self-identified as primarily educators, performers, or both; the age of the students who are taught. Additionally, the study addresses teachers’ statements about the use of competitions, dialogue in lessons, and general attitudes about the appropriateness of citizenship education in several different learning environments. The study findings add to a small but growing body of research that furthers understandings of the links between citizenship education and music education. In addition, the findings contribute to our understanding of the complexity of the relationship between private teachers and their students.
Nikolaj Ivanovič Nikolaev, La critica non ufficiale al «metodo formale» nella cultura russa degli anni ’20
Creators: name: Larocca, Giuseppina
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: La complessa e multiforme storia del formalismo russo è da tempo oggetto di ricerche che ne mettono a nudo tanto le contraddizioni e dispute interne quanto l’intricata rete di relazioni con personalità di circoli e gruppi critico-letterari contemporanei. Lo studio che viene qui presentato in traduzione – la seconda di tre parti – mira a far luce sulla storia della critica non ufficiale al formalismo, ovvero sulla storia di tutti quegli intellettuali – singoli o appartenenti a precise correnti estetico-letterarie – che, ora a Mosca, ora a Pietrogrado/Leningrado, hanno offerto un’alternativa metodologica alla pratica critica del gruppo di Ėjchenbaum. Attenzione privilegiata viene qui riservata all’attività di studiosi come Grigorij Vinokur e Viktor Žirmunskij, così come anche a quella dei seguaci e allievi del filosofo Gustav Špet operanti presso la GAChN moscovita.
description: ENTHYMEMA, N° 4 (2011)
title: Neutralising myostatin/activin signalling via sActRIIB to maintain skeletal muscle mass in rodent models of human diseases
Creators: name: Alqallaf, Ali A Kh R
Publisher: name: University of Reading
Year: 2023

description: Skeletal muscle loss is a feature of many human disease conditions. Importantly, maintaining 
muscle mass is a prognostic indicator of good health with local and systemic effects. Considerable
research has been conducted to develop therapies for muscle-wasting conditions. One of the most 
attractive means to achieve this goal is through the inhibition of the myostatin/activin signalling pathway. 
Here, we hypothesise that the application of this approach would maintain skeletal muscle mass in a 
diverse range of rodent models for muscle wasting with different underlying causes, ranging from acute 
to chronic conditions: Sickle-Cell Disease, Duchenne Muscular Dystrophy, Limb-Girdle Muscular 
Dystrophy and Peritonitis. The study investigated the effects on body and skeletal muscle weights, 
functional and physiological parameters, skeletal muscle pathology and morphometrics, gene expression 
in skeletal muscle and off-target effects. Antagonising myostatin/activin signalling pathway did not affect 
the body weight of the rodent model for Sickle-Cell Disease, Duchenne Muscular Dystrophy and early 
stages of Limb-Girdle Muscular Dystrophy and Peritonitis. In contrast, the body weight of older Sgca-null 
mice was decreased while the body weight at the resolving stage of the Peritonitis model was increased.
Furthermore, all rodent models increased skeletal muscle weight, except in the early stage of Peritonitis. 
The increased skeletal muscle weight was associated with muscle fibre hypertrophy in all rodent models. 
Functional analysis revealed an increased specific titanic force in D2.mdx mice but did not affect mdx mice, 
while the Sgca-null mice two limb hanging tests were decreased by myostatin/activin inhibition. No effect 
was observed in the functional parameters of the Peritonitis model. Off-target effects were observed in 
decreased splenomegaly in the Sickle-Cell Disease mouse model and a multi-organ weight decrease in the 
Duchenne Muscular Dystrophy mouse models (testes and kidneys). Therefore, in some but not all cases, 
myostatin/activin inhibition exhibited benefits but has limitations. Here, we propose that it is vital to
understand the mechanisms underpinning muscle wasting via recent advances in spatial transcriptomics,
as they may occur without the involvement of myostatin/activin signalling. Furthermore, we suggest 
combinational intervention may result in robust muscle growth where one arm involves myostatin/activin 
inhibition and the other a gene therapy.
GATA4 Partners in Cardiac Cell Proliferation
Creators: name: Yamak, Fatimah Abir
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Heart
Proliferation
GATA4
Congenital Heart Defects
Cell Cycle
Cyclin D2
KLF13

description: Cardiovascular diseases are the leading cause of death in humans throughout the world and “congenital heart defects” (CHDs) are the major cause of infant mortality and morbidity. GATA4 is one of the most critical and intensely studied cardiac transcription factor. It is important for proliferation of cardiomyocytes as well as their survival and adaptive response. The focus of the following thesis was to identify GATA4 mediators and cofactors in cardiac growth. The first part focused on cyclin D2 (CycD2), a growth inducible cell cycle protein. We identified Ccnd2 (gene encoding CycD2) as a direct transcriptional target of GATA4 in postnatal cardiomyocytes and Ccnd2 cardiomyocyte specific overexpression in Gata4 heterozygote mice was able to rescue their heart size and function. We further uncovered a novel regulatory loop between GATA4 and CycD2. CycD2 enhanced GATA4 activation of its target promoters. GATA4 was able to physically interact with CycD2 and its cyclin dependent kinase CDK4 suggesting that GATA4 recruits CycD2/CDK4 to its target promoters. Together, our data uncover a role of CycD2 in the developing and postnatal heart and provide novel insight for the potential of targeting the cell cycle in cardiac therapy. The second part of the project focused on KLF13, a cell specific cofactor of GATA4. KLF13 is a member of the Krϋppel-like transcription factors that are important regulators of cell proliferation and differentiation. Klf13 is highly enriched in the developing heart where it is found in both myocardial and endocardial cells. To determine its role in the mammalian heart, we deleted the Klf13 gene in transgenic mice. Klf13-/- mice were born at 50% reduced frequency and presented with variable cardiac phenotypes. Epithelial-mesenchymal transformation (EMT) was affected in these mice and reduced cell proliferation was evident in the AV cushion. These data uncover a role for a new class of transcription factors in heart formation and point to KLF13 as a regulator of endocardial cell proliferation and a potential CHD causing gene. Future discovery of more cardiac regulators and understanding the molecular basis of CHDs is essential for preventions of these defects and possible development of therapeutic approaches for myocardial repair.
The role of values in graduate performance in cross-cultural and innovation education
Creators: name: Seemann, Kurt
Publisher: name: Swinburne
Year: 2024

description: This paper provides authentic case study examples of how the role of values contributes directly and indirectly to task performance of graduates from cross-cultural to innovation education programs focussed on the study of technologies. Values have long been regarded by many stakeholders concerned with the output of technology education courses as an essential element, whether these courses are vocationally, professionally or developmentally oriented (Australian Science Technology and Engineering Council, 1996; Department of Education Science and Training, 2003b; Schwartz, Merten, and Bursik, 1986; Seemann, 1997; Walker and Seemann, 1990). However, there is minimal literature available linking how values may be a factor in shaping graduate performance or in the e ective delivery of contemporary educational content in case study and authentic situations. Two case studies are critiqued in terms of the role values played in forging skill and task performance. The First case study presents learning in a vocationally oriented cross-cultural and Australian indigenous outback technology education context. The second case study presents the shift in values expected for the new economy and its role in developing professional graduates in secondary technology education where the focus is on innovation education and new pedagogy practice. The paper discusses comparisons and highlights contrasts between the two case study contexts and offers the reader a basis to plan more e ective educational experience that may lead to improved graduate attributes and performance.
Differential Depletion of Bone Marrow Resident B-ALL after Systemic Administration of Endosomal TLR Agonists
Creators: name: Jo, Sumin
name: Fotovati, Abbas
name: Duque-Afonso, Jesus
name: Cleary, Michael L.
name: Van Den Elzen, Peter
name: Seif, Alix E.
name: Reid, Gregor S. D.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. While frontline chemotherapy regimens are generally very effective, the prognosis for patients whose leukemia returns remains poor. The presence of measurable residual disease (MRD) in bone marrow at the completion of induction therapy is the strongest predictor of relapse, suggesting that strategies to eliminate the residual leukemic blasts from this niche could reduce the incidence of recurrence. We have previously reported that toll-like receptor (TLR) agonists achieve durable T cell-mediated protection in transplantable cell line-based models of B cell precursor leukemia (B-ALL). However, the successful application of TLR agonist therapy in an MRD setting would require the induction of anti-leukemic immune activity specifically in the bone marrow, a site of the chemotherapy-resistant leukemic blasts. In this study, we compare the organ-specific depletion of human and mouse primary B-ALL cells after systemic administration of endosomal TLR agonists. Despite comparable splenic responses, only the TLR9 agonist induced strong innate immune responses in the bone marrow and achieved a near-complete elimination of B-ALL cells. This pattern of response was associated with the most significantly prolonged disease-free survival. Overall, our findings identify innate immune activity in the bone marrow that is associated with durable TLR-induced protection against B-ALL outgrowth.
Epifania dell’astanza. Brandi, Joyce e il modernismo tradito
Creators: name: Borsa, Davide
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: Davide Borsa analizza prestiti terminologici, riuso, invenzioni e ‘fossili’ lessicali come epifania, fulgurazione, astanza, nell’opera, nell’estetica e nel linguaggio di Cesare Brandi, individuando alcune caratteristiche dell’archetipo letterario italiano nel delicato momento di transizione dal postcrocianesimo allo strutturalismo, approfondendone alcune costanti ideologiche. Pur muovendosi nel segno della ricerca della continuità nei valori tradizionali, Brandi compie un’originale rilettura dell’avanguardia europea modernista e di Joyce che gli consentirà di sviluppare un originale approccio terminologico al restauro e all’estetica.
description: ENTHYMEMA, N° 4 (2011)
Supplementary document for High-responsivity Broadband Photodetection of ultra-thin In₂S₃/CIGS Heterojunction on Steel - 5194090.pdf
Creators: name: Zeng, Xi
name: Lontchi, Jackson
name: Zhukova, Maria
name: Fourdrinier, Lionel
name: Qadir, Israr
name: Ren, Yi
name: Niemi, Esko
name: Li, Guoli
name: Flandre, Denis
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Fabrication, characterization methods and photoelectrical performances at 680nm
Using the Amazon metric to construct an image database based on what people do, not what they say
Creators: name: Wyeld, Theodor G.
name: Colomb, Robert M.
Publisher: name: Swinburne
Year: 2024

description: Current image database metadata schemas require users to adopt a specific text-based vocabulary. Textbased metadata is good for searching but not for browsing. Existing image-based search facilities, on the other hand, are highly specialised and so suffer similar problems. Wexelblat?s semantic dimensional spatial visualisation schemas go some way towards addressing this problem by making both searching and browsing more accessible to the user in a single interface. But the question of how and what initial metadata to enter a database remains. Different people see different things in an image and will organise a collection in equally diverse ways. However, we can find some similarity across groups of users regardless of their reasoning. For example, a search on Amozon.com returns other products also, based on an averaging of how users navigate the database. In this paper we report on applying this concept to a set of images for which we have visualised them using traditional methods and the Amazon.com method. We report on the findings of this comparative investigation in a case study setting involving a group of randomly selected participants. We conclude with the recommendation that in combination, the traditional and averaging methods would provide an enhancement to current database visualisation, searching, and browsing facilities.
The Relative Roles of Herbivore- and Pollinator-mediated Selection on the Evolution of Floral Display in the Invasive Plant, Lythrum salicaria
Creators: name: Thomsen, Christina
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Floral trait evolution
Selection gradients
Herbivory
Pollinator-mediated selection
Pollen limitation
Compensatory growth

description: Studies assessing the evolution of plant traits frequently focus on pollinators as the primary drivers of floral trait evolution. However, herbivores can also play a role, and, under some circumstances, may even impose stronger selection on floral display than pollinators. This is especially true when the traits under selection are linked to anti-herbivore defense. Here I describe a study in which I quantified the relative role of herbivores and pollinators in selection for floral traits in the North American invasive plant, purple loosestrife (Lythrum salicaria). Because L. salicaria responds to leaf-chewing herbivores by producing compensatory tissue growth, and this in turn alters the architecture of the floral display, I further tested whether herbivores can indirectly modify pollinator-mediated selection through this pathway. Using a split-plot design, I measured pollen limitation and reproductive output in experimentally manipulated plants in the presence and absence of simulated herbivore damage in order to quantify the effects of damage and pollination on natural selection for floral display. My results showed that damage significantly increased direct selection (beta-i) for earlier flowering time and decreased selection on the number of inflorescences, even more than pollinators did. Because damage did not modify pollinator-mediated selection for floral display traits, the selection imposed by herbivores is likely only having direct effects. My findings demonstrate the importance of considering multiple agents of selection and their potential interactions when quantifying natural selection in a study system. In particular, it is important to consider that the agent most frequently studied may not be imposing the brunt of selection.
A model driven engineering approach for flexible and distributed monitoring of cross-cloud applications
Creators: name: Baur, Daniel
name: Griesinger, Frank
name: Verginadis, Yiannis
name: Stefanidis, Vasilis
name: Patiniotakis, Ioannis
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Complex event processing
subject: DDC 004 / Data processing & computer science
subject: Cloud computing
subject: Monitoring
subject: Event processing (Computer science)
subject: Programming (Mathematics)

description: Cloud computing and its computing as a utility paradigm offers on-demand resources, enabling its users to seamlessly adapt applications to the current demand. With its (virtually) unlimited elasticity, managing deployed applications becomes more and more complex raising the need for automation. Such autonomous systems leverage the importance to constantly monitor and analyse the deployed workload and the underlying infrastructure serving as knowledge-base for deriving corrective actions like scaling. Existing monitoring solutions, however are not designed to cope with a frequently changing topology. We propose a monitoring and event processing framework following a model-driven approach, that allows users to express i) the monitoring demand by directly referencing entities of the deployment context, ii) aggregate the monitoring data using mathematical expressions, iii) trigger and process events based on the monitoring data and finally iv) attach scalability rules to those events. We accompany the modelling language with a monitoring orchestration and distributed complex event processing framework, capable of enacting the model in a frequently changing multi-cloud infrastructure, considering cloud-specific aspects like communication costs.
Evaluation of an Enhanced (Sialyl Lewis-X) Collagen Matrix for Neovascularization and Myogenesis in a Mouse Model of Myocardial Infarction
Creators: name: Sofrenovic, Tanja
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Myocardial Infarction
Collagen Scaffold
Vasculogenesis
Cryopreservation
Peripheral Blood Mononuclear Cells
Circulating Angiogenic Cells

description: In cardiovascular disease the repair response is insufficient to restore blood flow, leading to the death of muscle and loss of tissue function. Therefore, strategies to augment the endogenous cell response and its effects may help improve tissue recovery and function. In this study we explored the use of tissue-engineered collagen matrices for augmenting endogenous regenerative processes after myocardial infarction. Treatment with the sLeX-collagen matrix reduced inflammation and apoptosis and had a positive regenerative effect on the infarcted mouse heart, through improved vascular density and possibly enhanced cardiomyogenesis. Additionally, we investigated the effects of cryopreservation on generating circulating angiogenic cells (CACs) from peripheral blood mononuclear cells (PBMCs), as a potential source of stem cells that could be used in combination with our collagen scaffold. Our findings show that despite PBMCs experiencing phenotypic changes after cryopreservation, they may still be used to generate the same therapeutic CACs as freshly procured PBMCs.
Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment
Creators: name: Medeiros, Braeden
name: Goodale, David
name: Postenka, Carl
name: Lowes, Lori E.
name: Kiser, Patti
name: Hearn, Stephen
name: Salmond, Nikki
name: Williams, Karla C.
name: Allan, Alison L.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: The lung is one of the deadliest sites of breast cancer metastasis, particularly in patients with triple-negative (TN) disease. We hypothesized that the presence of a TN primary breast tumor induces changes in the extracellular matrix (ECM) and soluble components of the lung microenvironment that support metastatic behavior. SUM159 (TN) and MCF7 (luminal A) breast cancer cells were injected into mice, and primary breast tumors were established prior to assessing metastatic niche changes. We observed increased CD117+ hematopoietic progenitor cells in the bone marrow of SUM159 mice versus MCF7 or control mice (p < 0.05). Relative to mice bearing MCF7 tumors and non-tumor controls, mice bearing SUM159 tumors demonstrated enhanced expression of ECM proteins in the lung (fibronectin, tenascin-c and periostin), with similar changes observed in lung fibroblasts treated with extracellular vesicles (EVs) from TN breast cancer cells (p < 0.05). Exposure to lung-conditioned media (LCM) from SUM159 tumor-bearing mice resulted in increased migration/proliferation of both SUM159 and MCF7 cells relative to the control (p < 0.05). In contrast, LCM from MCF-7 tumor-bearing mice had no such effect. LCM from SUM159 tumor-bearing mice contained 16 unique proteins relative to other LCM conditions, including the metastasis-associated proteins CCL7, FGFR4, GM-CSF, MMP3, thrombospondin-1 and VEGF. These findings suggest for the first time that the TN breast cancer molecular subtype may be an important determinant of premetastatic changes to both the ECM and soluble components of the lung, potentially mediated via breast cancer-derived EVs.
Il campo dell'arte: regole e valori dell'istituzione letteraria
Creators: name: Avella, Paola
Publisher: name: Facoltà di Lettere e Filosofia - Università degli Studi di Milano
Year: 2011

description: Si considera in questo articolo il campo artistico, descritto da Pierre Bourdieu, come il teatro di una lotta per la conquista del monopolio della legittimità letteraria tra (dis)posizioni sociali, a cui corrispondono precise strategie simboliche, concorrenti. Viene, così, messo in discussione il mito della gratuità e del disinteresse del lavoro intellettuale insieme a quello dell’esperienza estetica come identificazione immediata e contemplazione dell’opera. Le istanze di legittimazione interne al campo, infatti, determinano i modi della produzione, ma anche quelli dell’appropriazione. Solo un fruitore dotato della competenza adeguata sarà in grado di riconoscere il valore esemplificazionale inscritto nel testo.
description: ENTHYMEMA, N° 4 (2011)
Multifrequency behaviour of the anomalous events of PSR J0922+0638
Creators: name: Shaifullah, G.
name: Tiburzi, C.
name: Oslowski, S.
name: Verbiest, J. P. W.
name: Szary, A.
name: Kunsemoller, J.
name: Horneffer, A.
name: Anderson, J.
name: Kramer, M.
name: Schwarz, D. J.
name: Mann, G.
name: Steinmetz, M.
name: Vocks, C.
Publisher: name: Swinburne
Year: 2024

description: PSR J0922+0638 (B0919+06) shows unexplained anomalous variations in the on-pulse phase, where the pulse appears to episodically move to an earlier longitude for a few tens of rotations before reverting to the usual phase for approximately several hundred to more than a thousand rotations. These events, where the pulse moves in phase by up to 5°, have been previously detected in observations from~300 to 2000 MHz.We present simultaneous observations from the Effelsberg 100-m radio telescope at 1350MHz and the Bornim (Potsdam) station of the LOw Frequency ARray at 150 MHz. Our observations present the first evidence for an absence of the anomalous phase-shifting behaviour at 150 MHz. Instead, the observed intensity at the usual pulse-phase typically decreases, often showing a pseudo-nulling feature corresponding to the times when phase shifts are observed at 1350 MHz. The presence of weak emission at the usual pulse-phase supports the theory that these shifts may result from processes similar to the 'profile-absorption' expected to operate for PSR J0814+7429 (B0809+74). A possible mechanism for this could be intrinsic variations of the emission within the pulsar's beam combined with absorption by expanding shells of electrons in the line of sight.
"Right People, Right Place, Right Time": Exploring the Creation of Synergy within the EnRiCH-Québec City Partnership
Creators: name: Gagnon, Elizabeth
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Community-based participatory research (CBPR)
Synergy
Partnerships
Dynamics of collaboration

description: Many public health and social issues faced by society today are multifaceted and require joint and collaborative efforts through health promotion partnerships. Community-based participatory research (CBPR) is one strategy that consists of engaging community stakeholders from various sectors to pool their expertise and resources in addressing health and social issues holistically. The literature indicates that the effectiveness of partnerships, such as those established within CBPR initiatives, is influenced by collaborative mechanisms that promote the creation of synergy among partners. There is, however, a lack of knowledge with regards to synergy and its key determinants in the context of health promotion partnerships. This qualitative thesis study is conducted as part of The EnRiCH Project, a CBPR initiative conducted in four communities across Canada, which aims at enhancing resilience and preparedness for disasters among high-risk populations. It explores the creation of synergy through the study of dynamics of collaboration shaping the EnRiCH-Québec City partnership and influencing its ability to leverage community resources for emergency preparedness. Emergent themes highlight that optimal collaboration in the EnRiCH-Québec City partnership is about having the “right people, in the right place, at the right time”. These findings provide evidence to inform community stakeholders, researchers and decision-makers on the dynamics of synergy creation and its implications for partnership growth and effectiveness.
Acknowledging Brazil : the cinema of Joel Zito Araujo
Creators: name: Luz, Glauber Carvalho
Publisher: name: Southern Cross University
Year: 2020
Subjects: Documentary
Activism
Racial issues
Black genocide

description: Acknowledging Brazil – The Cinema of Joel Zito Araujo is a documentary film of one of the strongest voices on racial issues in Brazil, the much underrated black Brazilian filmmaker Joel Zito Araujo. This research/documentary examines Araujo’s cinema and academic work, growing up as a black Brazilian, and the motivations and struggles of the most prolific black documentary Brazilian filmmaker. Intertwining Araujo’s body of work and his own life experiences with past and recent alarming statistics on racism and black issues, the aim of this research is to underpin Araujo’s argument that inequality in Brazil has always been racial not social.
title: Diagnostic accuracy of Savanna RVP4 (QuidelOrtho) for the detection of Influenza A virus, RSV, and SARS-CoV-2
Creators: name: Köse, Büsra
name: Schaumburg, Frieder
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2024
Subjects: subject: 610 Medicine and health

description: Seasonal increase of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus A/B (Flu A/B), and respiratory syncytial virus (RSV) require rapid diagnostic test methods for the management of respiratory tract infections. In this study, we compared the diagnostic accuracy of Savanna RVP4 (RVP4, QuidelOrtho) with Xpert Xpress Plus SARS-CoV-2/Flu/RSV (Xpert, Cepheid). Nasopharyngeal swabs from patients treated at a tertiary care hospital (Germany) were tested for SARS-CoV-2, Flu A/B, and RSV by RVP4 to assess diagnostic accuracy (reference standard: Xpert). The intra and inter assay precision of Ct-values was assessed by repeated test in triplicates (on day 1) and duplicates (days 2–3). All patients with a physician’s order for a multiplex test for SARS-CoV-2, Flu, and RSV test were included. Duplicate swabs from the same patient, samples with a total volume ≤1 mL, or inappropriate shipment/storage were excluded. In total, 229 swabs were included between September 2023 and February 2024. The concordance between both tests was 96.5% (SARS-CoV-2), 98.7% (Flu A), and 99.6% (RSV). Flu B was not detected by both tests. The RVP4 test had a sensitivity of 85%–95% and a specificity of 100% for the detection of SARS-CoV-2, Flu A, and RSV. The intra and inter assay precision of Ct-values from RVP4 was 3% and 2% (SARS-CoV-2), 5% and 4% (Flu A), and 0% and 3% (RSV), respectively. The Savanna RVP4 has a favorable diagnostic accuracy for the detection of SARS-CoV-2, Flu A, and RSV.
description: Finanziert durch den Open-Access-Publikationsfonds der Universität Münster.
All‐conjugated polymer core–shell and core–shell–shell particles with tunable emission profiles and white light emission
Creators: name: Hähnle, Bastian
name: Schuster, Philipp A.
name: Chen, Lisa
name: Kühne, Alexander J. C.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: conjugated polymer particles
subject: core–shell particles
subject: white light emission
subject: DDC 540 / Chemistry & allied sciences
subject: Conjugated polymers
subject: Light-emitting electrochemical cells
subject: Konjugierte Polymere

description: Abstract Future applications of conjugated polymer particles (CPP) in medicine, organic photonics, and optoelectronics greatly depend on high performance and precisely adjustable optical properties of the particles. To meet these criteria, current particle systems often combine conjugated polymers with inorganic particles in core–shell geometries, extending the possible optical characteristics of CPP. However, current conjugated polymer particles are restricted to a single polymer phase composed of a distinct polymer or a polymer blend. Here, a synthetic toolbox is presented that enables the synthesis of monodisperse core–shell and core–shell–shell particles, which consist entirely of conjugated polymers but of different types in the core and the shells. Seeded and fed‐batch dispersion polymerizations based on Suzuki–Miyaura‐type cross‐coupling are investigated. The different approaches allow accurate control over the created interface between the conjugated polymer phases and thus also over the energy transfer phenomena between them. This approach opens up completely new synthetic freedom for fine tuning of the optical properties of CPP, enabling, for example, the synthesis of individual white light‐emitting particles.
description: Core–shell and core–shell–shell conjugated polymer particles are synthesized via seeded and fed‐batch dispersion polymerization. Depending on the method, the interface between the core and the shell polymers is either sharp or a gradual transition. The optical properties of the resulting particles can be fine‐tuned in such way, that the particles are emitting white light. image
Integrating Sectoral Ocean Policies
Creators: name: Salomon, Markus
name: Dross, Miriam
Publisher: name: My University
Year: 2018
Subjects: Ökosystemarer Ansatz
Maritime Raumordnung

description: Oceans and seas are adversely affected by a large number of anthropogenic pressures. The need to better integrate the policies of different sectors, which impact the oceans is generally seen. Different countries strive to implement a more integrated approach for the management and protection of their marine areas. Important tools which can support this process are marine spatial planning and marine protected areas. If a single administrative body is made responsible for the entire task of sustainable marine use and conservation, this could help to bundle responsibilities. Existing approaches often do not meet expectations. Reasons for this are diverse, ranging from insufficient governmental and scientific resources, lack of political will or a federal political system that complicates cooperation and coordination. © Springer International Publishing AG 2018
Women ICT students: the paradox of invisibility and visibility
Creators: name: Lewis, Sue
name: Lang, Catherine
name: McKay, Judith
Publisher: name: Swinburne
Year: 2024

description: If half of our young women studying information and communication technologies come from overseas and from single-sex schools, are at an age when they are vulnerable to evaluating themselves negatively even when they are high achievers, have less background experience of computers and less computer confidence from a range of previous gendered experiences at home and school, learn better in a learning centred rather than performance centred classroom, prefer the socio-technical contextual curriculum over the abstract ... then why are these findings consistently ignored? Despite numerous studies replicating each other, why are the needs of these women pedagogically invisible?