cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Acqua sulla Terra: tutto merito di Theia
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2019

La Terra è un pianeta abitabile grazie al nostro satellite naturale e alla collisione che ne è all’origine, dice uno studio pubblicato su Nature Astronomy. L’impattatore proveniva dal Sistema solare esterno, la sorgente dell’ingrediente fondamentale della vita terrestre: l’acqua. Il materiale carbonaceo espulso durante l’impatto sarebbe ricaduto sul nostro pianeta, fornendo l’acqua necessaria alla vita
Radio source feedback in galaxy evolution
Creators: name: Shabala, Stanislav
name: Alexander, Paul
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a galaxy evolution model which incorporates a physically motivated implementation of AGN feedback. Intermittent jets inflate cocoons of radio plasma which then expand supersonically, shock heating the ambient gas. The model reproduces observed star formation histories to the highest redshifts for which reliable data exists, as well as the observed galaxy colour bimodality. Intermittent radio source feedback also naturally provides a way of keeping the black hole and spheroid growth in step. We find possible evidence for a top-heavy Initial Mass Function (IMF) for $z>2$, consistent with observations of element abundances, and sub-mm and Lyman break galaxy counts.
description: 37 pages, 14 figures, ApJ (in press)
Companion (2025) and Toxic Transactional Relationships: Social Exchange Theory
Creators: name: Vince D. Amante
Publisher: name: Zenodo
Year: 2025

description: The 2025 sci-fi thriller Companion, directed by Drew Hancock, has been widely interpreted as a critique of toxic masculinity, particularly in its portrayal of male entitlement, control, and gender dynamics. However, this paper argues that the film is better understood as an exploration of transactional relationships rather than solely a critique of patriarchal structures. By applying Social Exchange Theory (SET) (Homans, 1958; Blau, 1964), we can reframe Companion as a study of mutual manipulation and the commodification of intimacy in modern relationships. This analysis examines how the characters of both Josh and Kat engage in exploitative behaviors for personal gain, reflecting broader social patterns of relational dependency, power imbalances, and self-interest.
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance
Creators: name: Castriconi, Roberta
name: Dondero, Alessandra
name: Pastorino, Fabio
name: Della Chiesa, Mariella
name: Corrias, Maria Valeria
name: Morandi, Fabio
name: Pistoia, Vito
name: Olive, Daniel
name: Bellora, Franesca
name: Locatelli, Franco
name: Castellano, Aurora
name: Moretta, Lorenzo
name: Bottino, Cristina
name: Moretta, Alessandro
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Anti-tumor immunity; Immune checkpoints; Neuroblastoma; Natural Killer cells; T cells; PD-1; PD-L1; PD-L2; INF-γ TNF-a

description: Neuroblastomas (NB) are neuroectodermal tumors that account for 15% of all childhood cancer deaths. Different prognostic factors including age, stage and amplification of MYCN (MYCNampl), are critical for defining NB risk and for guiding therapeutic choices1. In this context, although different strategies have been approached, the prognosis of high-risk neuroblastoma (NB) remains poor due the high frequency of relapse which not only occurs at the primary tumor site but frequently arises in the bone marrow. Thus, in vivo, neuroblastoma exploits different mechanisms to escape the immune surveillance2. These might include the so called “adaptive immune resistance” characterized by the de-novo expression of Programmed Death Ligands (PD-Ls)3 induced by IFN-γ whose storm occurs after different immunotherapeutic approaches. In the present study we analyzed the constitutive and the inducible surface expression of PD-Ls in NB cells. We showed that PD-L1 is constitutively express by virtually all HLA class Ipos NB cell lines, whereas PD-L2 is rarely detected. Moreover PD-L1 could be acquired/upregulated in both NB cell lines and NB engrafted nude/nude mice. Importantly, after IFN-γ stimulation, PD-L1 can be expressed by metastatic neuroblasts isolated from bone marrow aspirates of high-risk NB patients, characterized by different MYCN amplification status. Interesting- ly, in one case, metastatic neuroblasts were poorly responsive to IFN-γ stimulation, suggesting that responsiveness to IFN-γ might represent a further element of heterogeneity in metastatic neuroblasts. Finally, we documented the presence of PD-1-positive lymphocytes in NB-infiltrated bone marrow of patients. These cells are mainly represented by aβ T cells but also include small populations of gδ T cells and NK cells. Moreover, PD-1pos T cells expressed higher levels of activation markers as com- pared to the negative counterpart. Overall our data show that a PD-L1-mediated immune resistance mechanism might occur in metastatic neuroblasts and provide a biological rationale for blocking the PD-1/PD-Ls axis in future combined immunotherapeutic approaches.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Additional file 1 of Allelic phenotype prediction of phenylketonuria based on the machine learning method
Creators: name: Fang, Yang
name: Gao, Jinshuang
name: Guo, Yaqing
name: Li, Xiaole
name: Yuan, Enwu
name: Yuan, Erfeng
name: Song, Liying
name: Shi, Qianqian
name: Yu, Haiyang
name: Zhao, Dehua
name: Zhang, Linlin
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Additional file 1. Supplementary note. Encoding methods for structure and graph feature.
Kerbin chiama Terra: gara spaziale per studenti
Creators: Eliana Lacorte
Publisher: name: Media Inaf
Year: 2019

Si è tenuta ieri a Torino, presso l'Altec, la cerimonia di premiazione dei vincitori del progetto Cosmo Explorers, un esempio di didattica innovativa rivolto a studenti di scuole secondarie di primo e secondo grado. In cima al podio, l’Istituto Don Bosco di Cumiana e un team del Liceo Saffo di Roseto degli Abruzzi
La conta dei Fast Radio Burst
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2019

Sono sorgenti intensissime, brevissime e rilevate finora solo nella banda delle radio frequenze. Secondo uno studio pubblicato su Astronomy & Astrophysics, la loro durata e la loro potenza suggerisce che siano prodotte da fenomeni esplosivi probabilmente originati da stelle compatte
Proceedings Second International Workshop on Programming Language Approaches to Concurrency and Communication-cEntric Software
Creators: name: Beresford, Alastair R.
name: Gay, Simon
Publisher: name: arXiv
Year: 2010
Subjects: subject: Programming Languages (cs.PL)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences
subject: D.1.3; C.2.4; D.3.0

description: The Second International Workshop on Programming Language Approaches to Concurrency and Communication-cEntric Software (PLACES) was co-located with ETAPS 2009 in the city of York, England. The workshop took place on Sunday 22nd March 2009. The workshop focused on the challenges raised by the changing landscape of computer software. Traditionally, most software was written for a single computer with one CPU. However applications on the web today are built using numerous interacting services deployed on across many machines; soon off-the-shelf CPUs will host thousands of cores, and sensor networks will be composed from a large number of processing units. Many normal applications will soon need to make effective use of thousands of computing nodes. At some level of granularity, computation in such systems will be inherently concurrent and communication-centred. The development of effective programming methodologies for the coming computing paradigm demands exploration and understanding of a wide variety of ideas and techniques. This workshop offered a forum where researchers from different fields could exchange new ideas on one of the central challenges for programming in the near future, the development of programming methodologies and infrastructures where concurrency and distribution are the norm rather than a marginal concern.
title: ÐÐ½Ð°Ð»Ð¸Ð· Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¾ÑÐµÐ½ÐºÐ¸ Ð´Ð¾Ð· Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ, Ð¿Ð¾ÑÑÑÐ°Ð´Ð°Ð²ÑÐµÐ³Ð¾ Ð²ÑÐ»ÐµÐ´ÑÑÐ²Ð¸Ðµ Ð°Ð²Ð°ÑÐ¸Ð¸ Ð½Ð° Ð§ÐµÑÐ½Ð¾Ð±ÑÐ»ÑÑÐºÐ¾Ð¹ ÐÐ­Ð¡
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¡ÐµÑÐ¸ÐºÐ¾Ð²Ð°, ÐÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð¼ÐµÑÐ¾Ð´Ñ Ð¾ÑÐµÐ½ÐºÐ¸ Ð´Ð¾Ð·
Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ðµ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ
ÑÐ°Ð´Ð¸Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð°Ð²Ð°ÑÐ¸Ð¸
Ð´Ð¾Ð·Ð¸Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¼ÐµÑÐ¾Ð´Ñ
methods of evaluating doses
population exposure
radiation accidents
dosimetric methods

description: Ð Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ Ð¼ÐµÑÐ¾Ð´Ñ Ð¾ÑÐµÐ½ÐºÐ¸ Ð´Ð¾Ð· Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ°: Ð¾ÑÐµÐ½ÐºÐ° Ð´Ð¾Ð·Ñ Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ Ð¾Ñ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð¾Ð², ÑÐ¾Ð´ÐµÑÐ¶Ð°ÑÐ¸ÑÑÑ Ð² ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¾Ð¼ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ðµ; Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð±Ð¸Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¾Ð± ÑÐµÐ»Ð¾Ð²ÐµÐºÐ°; Ð¾Ð±ÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ Ð¡ÐÐ§ (ÑÑÐµÑÑÐ¸Ðº Ð¸Ð·Ð»ÑÑÐµÐ½Ð¸Ñ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ°); ÑÐ°ÑÑÐµÑ Ð¡ÐÐ­Ð (ÑÑÐµÐ´Ð½ÑÑ Ð³Ð¾Ð´Ð¾Ð²Ð°Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð°Ñ Ð´Ð¾Ð·Ð°). ÐÐ±ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÑÑÑÑ Ð´Ð°Ð½Ð½ÑÐµ ÑÐºÑÐ¿ÐµÐ´Ð¸ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð½ÑÑ Ð½Ð° ÑÐ°Ð´Ð¸Ð¾Ð°ÐºÑÐ¸Ð²Ð½Ð¾ Ð·Ð°Ð³ÑÑÐ·Ð½ÐµÐ½Ð½ÑÑ ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸ÑÑ, Ð¿Ð¾ÑÑÑÐ°Ð´Ð°Ð²ÑÐ¸Ñ Ð²ÑÐ»ÐµÐ´ÑÑÐ²Ð¸Ðµ Ð°Ð²Ð°ÑÐ¸Ð¸ Ð½Ð° Ð§ÐµÑÐ½Ð¾Ð±ÑÐ»ÑÑÐºÐ¾Ð¹ ÐÐ­Ð¡ (Ð°ÑÐ¾Ð¼Ð½Ð¾Ð¹ ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸Ð¸), Ð² Ð¾ÑÐ´Ð°Ð»ÐµÐ½Ð½ÑÐ¹ Ð¿ÐµÑÐ¸Ð¾Ð´ Ð¿Ð¾ÑÐ»Ðµ Ð°Ð²Ð°ÑÐ¸Ð¸. ÐÑÐ¿Ð¾Ð»Ð½ÑÐµÑÑÑ Ð¾ÑÐµÐ½ÐºÐ° ÑÐµÐºÑÑÐ¸Ñ Ð¡ÐÐ­Ð Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ, Ð¿ÑÐ¾Ð¶Ð¸Ð²Ð°ÑÑÐµÐ³Ð¾ Ð½Ð° ÑÐ°Ð´Ð¸Ð¾Ð°ÐºÑÐ¸Ð²Ð½Ð¾ Ð·Ð°Ð³ÑÑÐ·Ð½ÐµÐ½Ð½ÑÑ ÑÐµÑÑÐ¸ÑÐ¾ÑÐ¸ÑÑ. ÐÑÐ¿Ð¾Ð»Ð½ÑÐµÑÑÑ ÐºÐ°Ð»Ð¸Ð±ÑÐ¾Ð²ÐºÐ° Ð¡ÐÐ§, Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ ÐºÐ¾ÑÐ¾ÑÐ¾Ð³Ð¾ Ð¼Ð¾Ð¶Ð½Ð¾ Ð²ÑÐ¿Ð¾Ð»Ð½Ð¸ÑÑ Ð¾ÑÐµÐ½ÐºÑ Ð´Ð¾Ð·Ñ Ð²Ð½ÑÑÑÐµÐ½Ð½ÐµÐ³Ð¾ Ð¾Ð±Ð»ÑÑÐµÐ½Ð¸Ñ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ°.
description: In this graduate work there are different methods of evaluating doses of a human: evaluation procedure of radiation dose of radionuclides, containing in a human body; analysis human biological tests; investigation with human radiation spectrometer; estimation of average annual effective dose. There is also determined information from expeditionary researches, which were carried out at radioactive contaminated territories, suffered from the Chernobyl nuclear power plant accident in remote period after accident. In this work there are execution of current average annual effective dose estimation of people, who are living in radioactive contaminated territories and calibration of human radiation spectrometer. This spectrometer is executed for estimation of radiation dose of internal exposure of human.
HDACs expression in glioblastoma: an immunohistochemical study
Creators: name: Sferra, Roberta
name: Cicchinelli, Sara
name: Festuccia, Claudio
name: Battistini, Luca
name: Pompili, Simona
name: Vetuschi, Antonella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Glioblastoma; HDACs; immunohistochemistry

description: Glioblastoma is the most common and lethal primary malignant brain tumor. Although standard treatments have been improving, the clinical outcome remains unacceptably poor. Several genetic alterations are supposed to be involved in the eti- ology of different grades of astrocytoma, including epimutations. Histone deacety- lases (HDACs) are involved in the post-translational modification on the lysines of histone tails. For this reason HDACs are recognized as promising targets for cancer treatment (1). In the past several years, HDAC inhibitors (HDACis) have been used as radiosensitizers in glioblastoma treatment. However, no study has demonstrated the status of global HDAC expression in gliomas and its possible correlation to the use of HDACis (2). Aim of our study was to evaluate with an immunohistochemi- cal and immunoblotting analyses the expression of different classes of HDACs (Class I: HDAC 1-2-3-8; class II: HDAC 4-6) in microdissected glioblastoma. Tumor sam- ples were taken from 14 patients (n.8 men and n.6 women) ranging in age from 43 to 74 years. HDAC1 and HDAC3 expression was not significantly different between the two proteins and was predominantely located at cytoplasmic level of cancer cells with different intensity of immureaction from mild to moderate whereas HDAC2 staining was localized to the nucleous of neoplastic cells. The pattern of HDAC4 immureactivity was always cytoplasmatic and showed a marked and diffuse increase of immunostaining in neoplastic areas. HDAC8 was always absent in cancer cells and the only positivity was located in the endothelial cells of the vessels. HDAC6 was often absent and, if present, showed a very low cytoplasmic immunopositivity in cancer cells. HDAC1, HDAC2 and HDAC3 levels were not significantly different in immunoblotting results; HDAC4 showed a marked increase while HDAC6 and HDAC8 expression was poor, confirming the IHC data. These previous results dem- onstrate a different pattern of HDAC expression and could suggest a more addressed therapeutical use of HDACis in glioblastoma.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ
Creators: name: Cinti, Saverio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Adipose organ; obesity; transdifferentiation; mammary gland; pink adipocytes

description: In mammals, the adipocyte is a lipid-laden cell forming the parenchyma of a mul- ti-depot organ, the adipose organ. The white adipocyte stores lipids to release them, in the form of free fatty acids, during fasting, while the brown adipocyte burns glu- cose and lipids to perform thermogenesis. A recently characterized, third type of adi- pocyte does appear in the subcutaneous depot of the adipose organ of female mice during pregnancy and lactation: the pink adipocyte. The pink adipocytes are mam- mary gland alveolar epithelial cells with the essential role of producing and secret- ing milk for pup nourishment. Emerging evidence suggest that they derive from the transdifferentiation of the subcutaneous white adipocytes. Different metabolic and environmental challenges highlight the extraordinary plasticity of the mammalian adipose organ. Cold exposure leads to an increase of the “brown” component of the adipose organ to warrant thermal homeostasis. Under positive energy balance, the “white” component enlarges to a some extent to allow storage of the excess of nutri- ents. Finally, during pregnancy the “pink” component develops in the subcutaneous depots to satisfy pup nutritional needs. At cellular level, the plasticity of the adipose organ appears to occur not only through proliferation and differentiation of stem cells but, distinctively, via a direct transformation of fully-differentiated adipocytes that under proper stimuli by reprogramming their genetic expression change phenotype and, consequently, function. Understanding the transdifferentiation properties of the adipocytes is expected to offer not only new biological insights, but also possible therapeutic strategies to combat the metabolic syndrome (“browning”) and the breast cancer (“pinking”).
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Phleum phleoides
Creators: name: Cardona, Àngel Manuel Hernández
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Phleum
Phleum phleoides

description: Phleum phleoides (L.) H. Karst.
(flèum llarguerut). Present a una gran part d’Euràsia i en algunes localitats del nord d’Àfrica. Creix en clarianes de bosc, torrents i pastures humides, tant a les parts baixes com a les parts altes.
description: Published as part of Cardona, Àngel Manuel Hernández, 2022, Catàleg actualitzat i claus d'identificació de les gramínies de Sant Llorenç del Munt i l'Obac (Barcelona), pp. 64-86 in Nemus 12 on page 73, DOI: 10.5281/zenodo.12170499
A Licia Verde e a Irene Tamborra due premi Eas
Creators: Giuseppe Fiasconaro
Publisher: name: Media Inaf
Year: 2019

Dal 24 al 28 giugno prossimo, in occasione della European Week of Astronomy and Space Science, a Lione, in Francia, si terrà la annuale conferenza plenaria della European Astronomical Society (Eas), durante la quale verranno premiati i ricercatori che eccellono nei diversi campi dell'astrofisica e delle tecnologie.  Quest'anno, tra di essi, due nostre connazionali che lavorano all’estero, una a Barcellona e l’altra a Copenhagen
title: Ð¡Ð¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð°Ñ ÑÐ¸Ð»Ð¾ÑÐ¾ÑÐ¸Ñ
title: ÑÑÐµÐ±Ð½Ð¾-Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÑÐ»ÑÐºÐ¸Ð½, ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
name: Ð¡Ð¾ÐºÐ¾Ð»Ð¾Ð²Ð°, ÐÐ¸Ð½Ð°
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2013
Subjects: ÑÐ¸Ð»Ð¾ÑÐ¾ÑÐ¸Ñ
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: ÐÐ°Ð½Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð½Ð° ÑÐµÐ¼Ð¸Ð½Ð°ÑÑÐºÐ¸Ñ Ð·Ð°Ð½ÑÑÐ¸ÑÑ, Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð½ÑÑ Ð½Ð°Ð¸Ð±Ð¾Ð»ÐµÐµ Ð°ÐºÑÑÐ°Ð»ÑÐ½ÑÐ¼ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ð°Ð¼ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ ÑÐ¸Ð»Ð¾ÑÐ¾ÑÐ¸Ð¸ Ð¸ Ð¼Ð¾Ð¶ÐµÑ Ð±ÑÑÑ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¾ ÑÑÑÐ´ÐµÐ½ÑÐ°Ð¼ Ð² ÐºÐ°ÑÐµÑÑÐ²Ðµ ÑÐ¿ÑÐ°Ð²Ð¾ÑÐ½Ð¾Ð³Ð¾ Ð¸Ð·Ð´Ð°Ð½Ð¸Ñ Ð´Ð»Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ðº Ð·Ð°Ð½ÑÑÐ¸ÑÐ¼, Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸Ð¼ÑÐ¼ Ð¿Ð¾ ÐºÑÑÑÑ Â«Ð¤Ð¸Ð»Ð¾ÑÐ¾ÑÐ¸ÑÂ». Ð¡Ð¾Ð´ÐµÑÐ¶Ð°Ð½Ð¸Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÐµÑ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð¼Ñ ÑÑÐ°Ð½Ð´Ð°ÑÑÑ. ÐÐ¾ÑÐ¾Ð±Ð¸Ðµ Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð² ÑÐµÐ±Ñ ÐºÑÐ°ÑÐºÑÑ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ñ Ð¿Ð¾ Ð½ÐµÑÐºÐ¾Ð»ÑÐºÐ¸Ð¼ ÑÐµÐ¼Ð°Ð¼ , Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð´Ð»Ñ Ð¾Ð±ÑÑÐ¶Ð´ÐµÐ½Ð¸Ñ Ð¸ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ Ð·Ð½Ð°Ð½Ð¸Ð¹, ÑÐºÐ°Ð·Ð°Ð½Ð¸Ðµ Ð½Ð° Ð¿ÐµÑÐ²Ð¾Ð¸ÑÑÐ¾ÑÐ½Ð¸ÐºÐ¸ Ð¸ ÑÑÐµÐ±Ð½ÑÑ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÑ, Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼ÑÑ Ð´Ð»Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ (Ð²ÐºÐ»ÑÑÐ°Ñ ÑÑÑÐ»ÐºÐ¸ Ð½Ð° Ð¸Ð½ÑÐµÑÐ½ÐµÑ-ÑÐµÑÑÑÑÑ). ÐÐ»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð°ÑÐ¿Ð¸ÑÐ°Ð½ÑÐ¾Ð² Ð¸ Ð²ÑÐµÑ Ð¸Ð½ÑÐµÑÐµÑÑÑÑÐ¸ÑÑÑ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ð°Ð¼Ð¸ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ ÑÐ¸Ð»Ð¾ÑÐ¾ÑÑÐºÐ¾Ð¹ Ð¼ÑÑÐ»Ð¸.
description: ÐÐµÑÐ°ÑÐ°ÐµÑÑÑ Ð¿Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐµÐ´Ð°ÐºÑÐ¸Ð¾Ð½Ð½Ð¾-Ð¸Ð·Ð´Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð²ÐµÑÐ° Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ°.
Nutritional regulation of wound healing: the role of different amino acid mixture composition intake in wound repair. A preliminary study
Creators: name: Corsetti, Giovanni
name: Romano, Claudia
name: Flati, Vincenzo
name: Pasini, Evasio
name: Dioguardi, Francesco S.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Wound healing; amino acids

description: The ability of the skin to repair wounds requires immediate changes in metabolism and expression and silencing of the genes controlling cell proliferation, migration, adhesion and dif- ferentiation.
The energetic costs of wounds repair are enormous (1). Collagen represent around 50% of skin weight (about 20Kg), and synthesis costs are around 4 ATPs for any single amino acid (AA) inserted into the final composition of collagen (2). Moreover, the AA availability is indispensable to ensure the correct repair of the wound. Indeed, the poor state of dermal collagenous matrix is largely responsible for both the propensity to injury and slowness to heal observed in the elderly.
To test whether different formulation of AA mixture could improve wound repair, we fed male rats (14 months old) with three balanced diet containing 1) 100% essential AA mixture (EAA); 2) EAA 10% plus 90% non-essential (NE) AA (deficient diet - D) and 3) EAA 40% plus NEAA 60% (casein like diet – CL) for 30 days. Then, four excisional wound (diameter 5mm) were surgically made on dorsal skin of each animal. After 3, 15 and 30 post wound days (pwd) the wound area were measured, collected and analyzed by Sirius Red and IHC methods for TGFβ1 and Collagen 1. The D diet reduced weight of the animals up to 30% in 60 days although there was an increase of >18% of spontaneous caloric introduction, whereas the EAA and CL diets increased the rat weight of 6% and 12% respectively. Three pwd, the injured area in EAA and CL diets was 92% and 98% respect to day 0 (100%); whereas it was larger (120%) in D diet. Fif- teen pwd, the wounds were completely closed with EAA diet, whereas with CL and D diets the open area were 14% and 45% respectively. Thirty pwd, all wounds were closed but large scars were observed in D diet. TGFβ1 was early and strongly expressed in D diet, whereas it was much less expressed in EAA and CL diets. Sirius-red staining showed that the collagen architecture was more organized with EAA diet and less organized with D diet. Collagen was strongly expressed 15 pwd in CL diet and less expressed in D and EAA diets, whereas 30 pwd an intense staining was observed only in EAA diet. Our data show for the first time that malnutrition, diet rich in NEAA, seriously affects metabolism, leading to rapid decay of the animals and slows down the wound closure, due to dermal collagenous matrix impairment and collagen production, and pos- sibly related to excessive TGFβ1 expression. On the contrary, EAA diet controls expression of TGFβ1 and collagen production, accelerating the wound repair and blunting scarring.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Le coppia di stelle che visse due volte
Creators: Stefano Parisini
Publisher: name: Media Inaf
Year: 2019

Non sarà il finale di stagione del Trono di Spade, ma non mancano i colpi di scena nella storia di due stelline che, dopo essere vissute e morte assieme per miliardi di anni, si sono fuse in un corpo solo e riaccese. Ma il nuovo bagliore durerà poco, come spiega – spoilerando un po’ – l’articolo pubblicato su Nature
Is the Milky Way ringing? The hunt for high velocity streams
Creators: name: Minchev, I.
name: Quillen, A. C.
name: Williams, M.
name: Freeman, K. C.
name: Nordhaus, J.
name: Siebert, A.
name: Bienayme, O.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We perform numerical simulations of a stellar galactic disk with initial conditions chosen to represent an unrelaxed population which might have been left following a merger. Stars are unevenly distributed in radial action angle, though the disk is axisymmetric. The velocity distribution in the simulated Solar neighborhood exhibits waves traveling in the direction of positive v, where u,v are the radial and tangential velocity components. As the system relaxes and structure wraps in phase space, the features seen in the uv-plane move closer together. We show that these results can be obtained also by a semi-analytical method. We propose that this model could provide an explanation for the high velocity streams seen in the Solar neighborhood at approximate v in km/s, of -60 (HR 1614), -80 (Arifyanto and Fuchs 2006), -100 (Arcturus), and -160 (Klement et al. 2008). In addition, we predict four new features at v ~ -140, -120, 40 and 60 km/s. By matching the number and positions of the observed streams, we estimate that the Milky Way disk was strongly perturbed ~1.9 Gyr ago. This event could have been associated with Galactic bar formation.
description: 5 pages, 4 figures, Accepted to MNRAS Letters, added references
Anti-inflammatory effect of PDE5 inhibition in diabetic cardiomyopathy
Creators: name: Venneri, Mary Anna
name: Panio, Giuseppe
name: Isidori, Andrea
name: Naro, Fabio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Macrophages; cardiac hypertrophy; phosphodiesterase-5 inhibitor; diabetic mouse

description: In patients with type 2 diabetes PDE5 inhibition (PDE5i) is associated with cardiac remodeling and reduced inflammatory cytokines1. In this study it was investigated if PDE5 inhibition prevents the development of cardiomyocyte hypertrophy associated with diabetes by modulation of specific subsets of circulating monocytes and tissue macrophages. Leptin receptor–deficient db/db mice develop diabetes mellitus and cardiac hypertrophy. The db/db mice were treated with the PDE5 inhibitor sildenafil (SILD) for 8 weeks. In the hearts of SILD treated mice cardiomyocyte showed a reduced cross-sectional area compared to the cardiomyocyte of untreated mice. Expres- sion of the hypertrophic marker β-myosin was up-regulated in db/db mice hearts and this increase was prevented by SILD treatment. Circulating pro-inflammatory CD11b+Gr-1+ myeloid cells and the CD11b+Gr-1− monocyte cells, were monitored during SILD treatment. CD11b+Gr-1+ cells were reduced after SILD treatment in db/ db mice compared with untreated ones. No significant changes of CD11b+Gr-1− cells were detected in both control and SILD treated animals. After tissue dissociation, cardiac macrophages infiltration was characterized using specific markers such as F4/80 and TIE2. F4/80+ macrophages in diabetic mice were 2-fold increased compared to untreated mice and they were reduced by SILD treatment. Proangiogenic TIE2 expressing monocytes/macrophages (TEMs) percentage was highly increased in SILD treated db/db mice and correlated with an increase of vessel density, measured by the expression of the endothelial marker CD31. These data suggest that PDE5 inhibition attenuates inflammation in diabetic cardiomyopathy reducing pro-inflammatory monocytes and in parallel increasing TEMs percentage and tissue vascularization.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Size dependent thermoelectric properties of silicon nanowires
Creators: name: Shi, Lihong
name: Yao, Donglai
name: Zhang, Gang
name: Li, Baowen
Publisher: name: arXiv
Year: 2009
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: By using first-principles tight-binding electronic structure calculation and Boltzmann transport equation, we investigate the size dependence of thermoelectric properties of silicon nanowires (SiNWs). With cross section area increasing, the electrical conductivity increases slowly, while the Seebeck coefficient reduces remarkably. This leads to a quick reduction of cooling power factor with diameter. Moreover, the figure of merit also decreases with transverse size. Our results demonstrate that in thermoelectric application, NW with small diameter is preferred. We also predict that isotopic doping can increase the value of ZT significantly. With 50% 29Si doping (28Si0.529Si0.5 NW), the ZT can be increased by 31%.
description: 13 pages, 4 figures
Nei dettagli dell’ombra del buco nero
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2019

La nuova frontiera dell’osservazione dei buchi neri si chiama Event Horizon Imager, un sistema di radiotelescopi posizionati nello spazio che permetterà di raggiungere una risoluzione angolare di 4 microarcosecondi. Ne abbiamo parlato con Luciano Rezzolla, principal investigator di BlackHoleCam
The reductive condensation of 2,5-disubstituted pyrroles
Creators: name: White, James David
Publisher: name: University of British Columbia
Year: 2012

description: The problem initially presented was the structural elucidation of a compound obtained when 2,5-dimethylpyrrole was subjected to conditions of acidic reduction. Previous workers had assigned a molecular formula C₁₂H₁₇N to this product and a partial structure had been put forward based on the indolenine system. In the course of this work it was found that the compound obtained by these earlier workers was the result of a reductive self-condensation of 2,5-dimethylpyrrole, and Its structure was conclusively established as 1,3,4,7-tetramethylisoindoline. The methods used in the structural elucidation of this product included elemental analysis of its derivatives, measurement of its basicity and equivalent weight, infrared and ultraviolet spectroscopic evidence, oxidative degradation, and its proton magnetic resonance spectrum. Two related isoindolines were prepared by different routes. 2,4,7-trimethylisoindoline was synthesised by methods analogous to those already known, and the ultraviolet spectrum of its methiodide, when compared with that of the methiodide from 1,3,4,7-tetramethylisoindoline, reinforced the structural assignment of the latter. 1,3-diphenyl-4,7-dimethylisoindoline was obtained by the reductive condensation of acetonylacetone with 2,5-diphenylpyrrole (which did not undergo self-condensation). The favourable result of this reaction suggested that a similar condensation may have occurred to give the 1,3,4,7-tetramethylisoindoline and also admitted the possibility of a general synthesis of substituted isoindolines by this route. An attempt was made to resolve the mechanism of the 2,5-dimethylpyrrole condensation, for which either a Diels-Alder reaction or a ring-opening process may be postulated. The failure of the dimethylpyrrole to show dienic character, even in the presence of very strong dienophiles, together with positive evidence for ring-opening and ketone-pyrrole condensation argued forcibly for the latter mechanism.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÑÑÐµÐºÑÐ¾Ð² Ð´Ð»Ñ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸ Ð²ÐµÐ±-Ð¸Ð½ÑÐµÑÑÐµÐ¹ÑÐ¾Ð²
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÑÑÐ»Ð¾Ð²Ð°, ÐÐ»ÑÐ³Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÐÐ½ÑÐµÑÑÐµÐ¹ÑÑ
ÐÐ½ÑÐµÑÐ½ÐµÑ
ÐÐ°ÑÐ¸Ð½Ð½Ð°Ñ Ð³ÑÐ°ÑÐ¸ÐºÐ°
Ð²ÐµÐ±-Ð¸Ð½ÑÐµÑÑÐµÐ¹ÑÑ
ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸
Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ
Ð°Ð½Ð¸Ð¼Ð°ÑÐ¸Ñ

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ¾-Ð¾ÑÐ¸ÐµÐ½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½ÑÑ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼. Ð¦ÐµÐ»Ñ ÑÐ°Ð±Ð¾ÑÑ - ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð½Ð°Ð¸Ð±Ð¾Ð»ÐµÐµ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾Ð¹ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÑÑÐµÐºÑÐ¾Ð² Ð´Ð»Ñ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸ Ð²ÐµÐ±-Ð¸Ð½ÑÐµÑÑÐµÐ¹ÑÐ° Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÑÐ°Ð¹ÑÐ° ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½Ð¾Ð¹ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸. Ð Ð¿ÑÐ¾ÑÐµÑÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ ÑÐµÐ½Ð´ÐµÐ½ÑÐ¸Ð¹ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð²ÐµÐ±-Ð¸Ð½ÑÐµÑÑÐµÐ¹ÑÐ¾Ð², Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ð¾Ð² Ð¸ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¾ÑÐµÐ½ÐºÐ¸ ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð²Ð»Ð¸ÑÐ½Ð¸Ðµ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÑÑÐµÐºÑÐ¾Ð² Ð¸ Ð°Ð½Ð¸Ð¼Ð°ÑÐ¸Ð¸ Ð½Ð° ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸ Ð²ÐµÐ±-Ð¸Ð½ÑÐµÑÑÐµÐ¹ÑÐ°. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð²ÑÑÐ²Ð»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ñ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÑÑÐµÐºÑÐ¾Ð², ÑÐ¿Ð¾ÑÐ¾Ð±ÑÑÐ²ÑÑÑÐ¸Ñ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ ÑÐ·Ð°Ð±Ð¸Ð»Ð¸ÑÐ¸.
title: ÐÐ½Ð°Ð»Ð¸Ð· Ð¿ÑÐ¸ÑÐ¸Ð½ Ð¿Ð¾Ð¶Ð°ÑÐ¾Ð² Ð½Ð° Ð³Ð¸Ð´ÑÐ¾ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸ÑÑ Ð¸ Ð¿ÑÑÐ¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÑÐ±ÑÐ¸ÑÐºÐ¸Ð¹, ÐÐ°ÐºÑÐ¸Ð¼
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð³Ð¸Ð´ÑÐ¾ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸Ð¸
Ð¿Ð¾Ð¶Ð°ÑÐ½Ð°Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ
ÑÐ¿ÐµÑÐ¸ÑÐ¸ÐºÐ° ÑÑÑÐµÐ½Ð¸Ñ
ÑÑÐµÐ±Ð½ÑÐµ Ð¿Ð¾Ð¶Ð°ÑÑ
Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¿Ð¾Ð¶Ð°ÑÐ¾Ð² Ð½Ð° ÐÐ­Ð¡

description: ÐÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¸Ñ ÑÐµÐ¼Ñ: Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿ÑÐ¸ÑÐ¸Ð½ Ð¿Ð¾Ð¶Ð°ÑÐ¾Ð² Ð½Ð° Ð³Ð¸Ð´ÑÐ¾ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸ÑÑ Ð¸ Ð¿ÑÑÐ¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸. ÐÐ°ÑÐµÑÐ¸Ð°Ð»Ñ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±Ð°Ð·Ð¸ÑÑÑÑÑÑ Ð½Ð° Ð´Ð¾ÑÑÐ¸Ð³Ð½ÑÑÑÑ Ðº Ð½Ð°ÑÑÐ¾ÑÑÐµÐ¼Ñ Ð²ÑÐµÐ¼ÐµÐ½Ð¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ°Ñ Ð½Ð°ÑÑÐ½ÑÑ Ð´Ð¾ÑÑÐ¸Ð¶ÐµÐ½Ð¸Ð¹ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð¿Ð¾Ð¶Ð°ÑÐ½Ð¾Ð¹ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÑÑ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸ÑÐ¼ ÑÑÐºÐ¾Ð²Ð¾Ð´ÑÑÐ¸Ñ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ¾Ð².
Conquistati dalla Luna
Creators: Francesca Aloisio
Publisher: name: Media Inaf
Year: 2019

È uscito il nuovo libro dell’astrofisica Patrizia Caraveo, dedicato alla storia del rapporto speciale che lega l’uomo alla Luna. Pubblicato da Raffaello Cortina, il volume ripercorre la storia dell’attrazione che il nostro satellite ha sempre esercitato su di noi, da quando eravamo semplici osservatori per arrivare ai giorni nostri, in cui se ne pianifica lo sfruttamento commerciale. Un percorso affascinante per celebrare l’anniversario dei 50 anni dall’allunaggio. Ma è stato l’uomo a conquistare la Luna o è la Luna ad aver conquistato l’uomo?
Enhanced superconductivity of YBCO interfaces: origin of high critical temperature in layered superconductors
Creators: name: Tinchev, S. S.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Superconducting transition temperatures Tc of the YBCO film surface and of the YBCO film/substrate interface were measured inductively. It was observed that the interface- Tc is always higher then the surface - Tc. However deposition of silver over-layer enhances the superconducting transition temperatures. This observation was confirmed by four-point resistance measurements. In the annealed YBCO/Ag bilayers magnetic properties of the interface were observed. We believe that such phenomena are a common feature of layered systems. This two dimensional structure reminds the layered microstructure of the high-temperature superconductors and one can suppose that covering of the superconducting layer by non-superconducting layer is a condition for obtaining high critical temperatures in general.
description: 13 pages, 9 figures, submited to Nature
title: Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´ÐµÑÐ°Ð»Ð¸ Â«ÐÐ°Ð» Ð²ÐµÐ´ÑÑÐ¸Ð¹Â» Ñ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ°Ð¼Ð¸ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ð¸ Ð¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÑÐ°Ð½Ð¾Ð²Ð¾ÑÐ½Ð¾-Ð·Ð°Ð¶Ð¸Ð¼Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¸ÑÐ¿Ð¾ÑÐ¾Ð±Ð»ÐµÐ½Ð¸Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð²ÐµÐ»ÐºÐ¾, ÐÐ¼Ð¸ÑÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð²Ð°Ð»
Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ°
ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐµÐ·Ð°Ð½Ð¸Ñ
Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ðµ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾
ÑÐ¸ÐºÐ»Ð¾Ð³ÑÐ°Ð¼Ð¼Ð°

description: Ð Ð¿ÐµÑÐ²Ð¾Ð¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ° Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐ½Ð¾ÑÑÐ¸ Ð¾Ð±ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÐµÐ¼Ð¾Ð¹ Ð´ÐµÑÐ°Ð»Ð¸ â ÐÐ°Ð» Ð²ÑÑÐ¾Ð´Ð½Ð¾Ð¹, Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð²Ð¾Ð¿ÑÐ¾ÑÑ Ð²ÑÐ±Ð¾ÑÐ° Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð¸ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² ÐµÐµ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ° Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´ÐµÑÐ°Ð»Ð¸, Ð²ÑÐ±Ð¾Ñ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸ Ð¾ÑÐ½Ð°ÑÑÐºÐ¸, ÑÐ°ÑÑÐµÑ ÑÐµÐ¶Ð¸Ð¼Ð¾Ð² ÑÐµÐ·Ð°Ð½Ð¸Ñ Ð¸ Ð½Ð¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¹. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ° Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð¿Ð¾ÑÑÐ´Ð¾Ðº Ð²ÑÐ±Ð¾ÑÐ° Ð¸ ÑÐ°ÑÑÐµÑÐ° ÑÑÑÐ°Ð½Ð¾Ð²Ð¾ÑÐ½Ð¾-Ð·Ð°Ð¶Ð¸Ð¼Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¸ÑÐ¿Ð¾ÑÐ¾Ð±Ð»ÐµÐ½Ð¸Ñ: Ð ÑÑÐµÑÑÐµÐ¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ Ð¾Ð´Ð½Ð¾Ð³Ð¾ Ð¿ÐµÑÐµÑÐ¾Ð´Ð° Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸. ÐÑÐ»Ð¸ Ð²ÑÐ±ÑÐ°Ð½Ñ Ð¸ Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ðµ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾ Ð¸ Ð¾ÑÑÐµÐºÐ°ÑÐµÐ»Ñ. Ð¢Ð°ÐºÐ¶Ðµ Ð±ÑÐ» Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð° Ð¸ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð° ÑÐ¸ÐºÐ»Ð¾Ð³ÑÐ°Ð¼Ð¼Ð° ÑÐ°Ð±Ð¾ÑÑ Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð° Ð¸ ÑÑÐ°Ð½ÐºÐ°.
Infertility in Fabry’s disease: role of hypoxia and inflammation in determining testicular damage
Creators: name: De Santis, Elena
name: Arcangeli, Tania
name: Carnevale, Ilaria
name: Coppola, Luigi
name: D’Orazi, Valerio
name: Tafani, Marco
name: Russo, Matteo Antonio
name: Frustaci, Andrea
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Fabry’s disease (FD) is a genetic X-linked systemic and progressive rare disease, which is characterized by the accumulation of glycolipid bodies (GB) into the lys- osomes of almost all cell types and consequently by a multiform clinical picture. Here we studied testicular biopsies of a 42 ys old FD patient, presenting infertility with reduced number of spermatozoa and preserved sexual activity. Testicular biopsies have been analyzed by optical microscopy (OM) and transmis- sion electron microscopy (TEM). OM, showed a severe involvement of testis inter- stitium blood vessels with reduced or closed lumen, an increased of connective tis- sue and a substantial thicketing of peritubular region. TEM, showed that GB were abundant in vessel wall cells and in myofibroblast of peritubular region. In contrast with literature reports, Leydig cells were constantly unaffected by GB accumulation showing well preserved ultrastructural organization. On the contrary, tubular cells, although not affected by GB accumulation, appeared severely damaged. These data led us to hypothesize that diffusion of oxygen and nutrients from blood to tubules could be impaired. To test this hypothesis we explored, by immunofluorescence (IF) and molecular biology (MB) coupled to laser capture micro-dissection (LCMD), the activation of HIF/NFkB pathway. IF showed increased signal for HIF1a in all stromal components, while it appeared almost absent in seminipherous tubules. On the contrary, NFkB fluores- cence was evident in tubules. mRNA of tubular and interstitial tissue fractions, separately extracted by LCMD, confirms that HIF1a and hypoxic-related genes such as alarmin recepters (RAGE, TLR4) were overexpressed in the interstitial cells. At the same time, NFkB and a number of proinflammatory genes such as HMOX1, PTGES, SAA1-SAA2 were up- regulated in the tubule microenviroment. Taken together, these results suggest that the GB accumulation in interstitium, reducing vessel lumen and increasing the distance between vessel and tubular cells, leads to chronic progressive hypoxia. Hypoxia has two effects: 1)Necrosis of cells more distant from vessels, especially germinative epithelium and Sertoli cells, releas- ing alarmins; 2)Adaptation to low levels of O2, with activation of HIF1a. In both cas- es a strong activation of NFkB occurs that trigger a inflammatory response (IR). We suggest a role for the IR activation in determining intratubular cells damage and con- sequently, infertility in FD.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Pressure variations in cerebral venous sinuses of idiopathic intracranial hypertension patients
Creators: name: Zeenat Qureshi Stroke Institutes
Publisher: name: Zenodo
Year: 2023

description: Purpose

To evaluate the alteration of pressure characteristics in the cerebral venous sinuses before and after venous sinus stenting (VSS) using mean sinus pressures (MSPs), sinus pressure gradient (SPG), and sinus pressure pulsatility (SPP) parameters among the idiopathic intracranial hypertension (IIH) patients.

Materials and Methods

Prospective evaluation of 45 consecutive IIH patients who underwent VSS at our institution. A written informed consent approved by the Weill Cornell Institutional Review Board was signed by the study participants. All patients (n = 45) were evaluated for MSPs and SPG. In a subgroup of 12 (n = 12) consecutive patients, SPP was measured. MSP was measured using microcatheter at superior sagittal sinus (SSS), transverse sinus (TS), and sigmoid sinus (SS). SPG was measured as trans-stenotic gradient and trans-torcular gradient. SPP was recorded in the dominant TS with a six French intermediate catheter. Statistical analysis was performed using paired student t-test and two sample t-tests tested for both equal and unequal variances. P values below 0.05 were considered significant.

Results

The mean age of the study population was 30.6 ± 10 years (7–59 years) and 43 out of 45 are female patients. The mean weight and BMI of the study population were 96 ± 24.7 kg (30.8–144 kg) and 35.6 ± 8.3 kg/M2 (16.4–51.4 kg/M2), respectively. VSS in IIH patients resulted in immediate reduction of MSP in the SSS {Δ Mean: −8.1 mm Hg [95% confidence interval (CI): −5.0–11.7 mm Hg], p < 0.001} and TS [Δ Mean: −11.8 mm Hg (95% CI: −7.5 to 13.4 mm Hg), p < 0.001] and increase of MSP in SS [Δ Mean: 7.5 mm Hg (95% CI: 6–10.1 mm Hg), p < 0.001]. Significant reduction of trans-stenotic SPG reduction [Δ Mean: −15.7 mm Hg (95% CI: −13.6–17.8 mm Hg), p < 0.001] and SPP [Δ Mean: −8 mm Hg (95% CI: −2.5–13.4 mm Hg), p < 0.05] was observed following VSS
Achromatizing a liquid-crystal spectropolarimeter: Retardance vs Stokes-based calibration of HiVIS
Creators: name: Harrington, D. M.
name: Kuhn, J. R.
name: Sennhauser, C.
name: Messersmith, E. J.
name: Thornton, R. J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Astronomical spectropolarimeters can be subject to many sources of systematic error which limit the precision and accuracy of the instrument. We present a calibration method for observing high-resolution polarized spectra using chromatic liquid-crystal variable retarders (LCVRs). These LCVRs allow for polarimetric modulation of the incident light without any moving optics at frequencies >10Hz. We demonstrate a calibration method using pure Stokes input states that enables an achromatization of the system. This Stokes-based deprojection method reproduces input polarization even though highly chromatic instrument effects exist. This process is first demonstrated in a laboratory spectropolarimeter where we characterize the LCVRs and show example deprojections. The process is then implemented the a newly upgraded HiVIS spectropolarimeter on the 3.67m AEOS telescope. The HiVIS spectropolarimeter has also been expanded to include broad-band full-Stokes spectropolarimetry using achromatic wave-plates in addition to the tunable full-Stokes polarimetric mode using LCVRs. These two new polarimetric modes in combination with a new polarimetric calibration unit provide a much more sensitive polarimetric package with greatly reduced systematic error.
description: Accepted in PASP
Le due facce della Luna: gemelle diverse
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2019

Un’asimmetria che è ancora un mistero ma che può essere spiegata, forse, grazie a 360 simulazioni computerizzate. La causa? Un oggetto che si è schiantato con il nostro satellite naturale all’alba del Sistema solare, provocando profondi cambiamenti sul lato nascosto
Luce verde per il misura-fotoni di Athena
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2019

Si chiama “X-ray Integral Field Unit” e sarà posto sul piano focale del telescopio spaziale Athena dell’Esa. Luigi Piro (Inaf): «Permetterà di misurare accuratamente l’energia dei fotoni osservati, grazie a un sensore innovativo basato sui microcalorimetri»
Getting adaptation right – challenges and ethical issues facing planners adapting to sea level rise in southern Sweden
Creators: name: Wedin, Anna
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Sea level rise (SLR) caused by climate change presents challenges for public planners all over the world. In this study, practical challenges and ethical factors in adaptation to SLR were identified based on interviews with planners in Sweden. Six challenges were identified: lack of knowledge and human resources, lacking integration and coordination, lacking or insufficient frameworks for dealing with long-time-horizons, responsibility for implementation and financing, and goal conflicts in the process of implementing adaptation policy. These challenges are then developed into a typology of ethical factors that are of particular importance for adaptation to SLR, categorised as input-oriented, process-oriented and outcome-oriented ethical factors. The challenges and ethical factors identified in this paper are the first step taken towards answering the question of what a sustainable and ethical adaptation to SLR in the context of local and regional policy-making could look like.
Blazar colto sul fatto: cronaca di un’osservazione
Creators: Paolo Soletta
Publisher: name: Media Inaf
Year: 2019

Noemi Iacolina, ricercatrice dell’Asi di stanza al Sardinia Radio Telescope (Srt), racconta a Media Inaf lo studio di follow up – condotto con i radiotelescopi di Medicina e Srt – di un brillamento del blazar Pks 1830-211 osservato da Agile alla fine di marzo
Permeability of a mountain-type Douglas fir stem containing included sapwood bands
Creators: name: Koran, Zoltan
Publisher: name: University of British Columbia
Year: 2012

description: Permeability to creosote of sapwood, included sapwood, and normal heartwood of a mountain-type Douglas fir stem was correlated with specific gravity, growth rate, percent summerwood, tracheid length, number of longitudinal resin ducts, alcohol-benzene, acetone and ether-soluble extractive contents of the corresponding zones. The effect of pressure and temperature on creosote retention was tested on creosote retention in true sapwood, included sapwood (abnormal heartwood), and normal heartwood. Test specimens were extracted in different solvents and ease of penetration tested by creosote impregnation. Among the factors investigated in the present study, specific gravity, tracheid length, growth rate, and number of longitudinal resin ducts did not have a measurable influence on creosote retention. Percent summerwood did not vary significantly at the five positions tested. Pressure had the greatest effect on creosote retention at 212°F. for heartwood, less for included sapwood and least for sapwood. The influence of temperature on creosote retention in Douglas fir heartwood was greater at 100 psi pressure than at atmospheric pressure. The effect of alcohol-benzene and acetone-soluble extractives on wood permeability was not proven statistically significant. A visual hyperbolic relationship was obtained between ether-soluble extractives and wood permeability. The higher the extractive content, the greater the retention. Pre-treatment of samples with different solvents, in order to remove some of the extractives, improved the permeability of heartwood and included sapwood significantly but caused only a slight improvement in sapwood.