cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Estimating syphilis seroprevalence among patients in a sexually transmitted infections clinic in Lilongwe, Malawi
Creators: name: Khan, S.
name: Lancaster, K.E.
name: Seña, A.C.
name: Jere, E.
name: Chen, J.S.
name: Ndalama, B.
name: Hoffman, I.F.
name: Matoga, M.
name: Massa, C.
name: Miller, W.C.
name: Hosseinipour, M.C.
name: Cohen, M.S.
Publisher: name: SAGE Publications Ltd
Year: 2020

description: The syndromic management of genital ulcer disease (GUD) misses asymptomatic syphilis cases but is widely utilized in resource-limited settings without diagnostic capabilities to ensure treatment for the most common etiologies of GUD. We used rapid serology tests for syphilis screening at a Malawian sexually transmitted infections clinic. The estimated seroprevalence was 9% and was highest among patients with genital ulcers (26%) and newly diagnosed HIV infection (19%). Rapid syphilis screening has the potential to increase syphilis detection, but accurate patient histories regarding syphilis diagnosis and prior treatment are needed.
On categories O for quantized symplectic resolutions
Creators: name: Losev, Ivan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 16E35, 16G99

description: In this paper we study categories O over quantizations of symplectic resolutions admitting Hamiltonian tori actions with finitely many fixed points. In this generality, these categories were introduced by Braden, Licata, Proudfoot and Webster. We establish a family of standardly stratified structures (in the sense of the author and Webster) on these categories O. We use these structures to study shuffling functors of Braden, Licata, Proudfoot and Webster (called cross-walling functors in this paper). Most importantly, we prove that all cross-walling functors are derived equivalences that define an action of the Deligne groupoid of a suitable real hyperplane arrangement.
description: 27 pages, v2 36 pages, new material added
Monoclonal Antibodies for Prevention and Treatment of COVID-19
Creators: name: Marovich, M.
name: Cohen, M.S.
name: Mascola, J.R.
Publisher: name: American Medical Association
Year: 2020

description: The coronavirus disease 2019 (COVID-19) pandemic has created a worldwide crisis and inspired an urgent search for prevention and treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Attention has focused on the development of vaccines, new antiviral agents, and convalescent plasma infusions. Monoclonal antibodies have received less attention even though neutralizing antibodies are a key component of protective immunity for most viral diseases. Neutralizing monoclonal antibodies to SARS-CoV-2 have the potential for both therapeutic and prophylactic applications, and can help to guide vaccine design and development.
SMT Solving over Finite Field Arithmetic
Creators: name: Hader, Thomas
name: Kaufmann, Daniela
name: Kovács, Laura
Publisher: name: arXiv
Year: 2023
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: Non-linear polynomial systems over finite fields are used to model functional behavior of cryptosystems, with applications in system security, computer cryptography, and post-quantum cryptography. Solving polynomial systems is also one of the most difficult problems in mathematics. In this paper, we propose an automated reasoning procedure for deciding the satisfiability of a system of non-linear equations over finite fields. We introduce zero decomposition techniques to prove that polynomial constraints over finite fields yield finite basis explanation functions. We use these explanation functions in model constructing satisfiability solving, allowing us to equip a CDCL-style search procedure with tailored theory reasoning in SMT solving over finite fields. We implemented our approach and provide a novel and effective reasoning prototype for non-linear arithmetic over finite fields.
Prevention of HIV Transmission and the HPTN 052 Study
Creators: name: McCauley, M.
name: Cohen, M.S.
name: Gamble, T.
Publisher: name: Annual Reviews Inc.
Year: 2020

description: The HIV Prevention Trials Network 052 study (HPTN 052) was a clinical trial designed to determine whether early treatment for HIV infection prevented transmission of the virus in couples where one partner was infected with HIV and the other was not, referred to as HIV serodiscordant or serodifferent couples. The study enrolled 1,763 couples at 13 sites in 9 countries in Asia, Africa, and the Americas. HPTN 052 demonstrated a minimum of 96% reduction of HIV in heterosexual couples ascribed to antiretroviral treatment; early treatment of HIV significantly reduced other infections in the HIV-infected subjects. This study, in conjunction with similar research, led to significant changes in international HIV treatment guidelines and the concept of treatment as prevention (TasP). This article provides the scientific background and history of how HPTN 052 came into being, the challenges it faced, and the ultimate impact it had on the fields of HIV treatment and prevention.
Elastohydrodynamics of a sliding, spinning and sedimenting cylinder near a soft wall
Creators: name: Salez, Thomas
name: Mahadevan, L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: We consider the motion of a fluid-immersed negatively buoyant particle in the vicinity of a thin compressible elastic wall, a situation that arises in a variety of technological and natural settings. We use scaling arguments to establish different regimes of sliding, and complement these estimates using thin-film lubrication dynamics to determine an asymptotic theory for the sedimentation, sliding, and spinning motions of a cylinder. The resulting theory takes the form of three coupled nonlinear singular-differential equations. Numerical integration of the resulting equations confirms our scaling relations and further yields a range of unexpected behaviours. Despite the low-Reynolds feature of the flow, we demonstrate that the particle can spontaneously oscillate when sliding, can generate lift via a Magnus-like effect, can undergo a spin-induced reversal effect, and also shows an unusual sedimentation singularity. Our description also allows us to address a sedimentation-sliding transition that can lead to the particle coasting over very long distances, similar to certain geophysical phenomena. Finally, we show that a small modification of our theory allows to generalize the results to account for additional effects such as wall poroelasticity.
Combination prevention for COVID-19
Creators: name: Corey, L.
name: Cohen, M.S.
Publisher: name: American Association for the Advancement of Science
Year: 2020

description: The coronavirus disease 2019 (COVID-19) pandemic has produced the fear and disorder inevitably provoked by emerging pathogens. As such, it should also inspire consideration of our experience with HIV over the past 40 years. As with HIV, the road to reducing infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the cause of COVID-19), and attendant morbidity and mortality, requires medical and nonmedical strategies. The most important lesson learned from tackling HIV is to use a combination of prevention strategies
A fresh look at the vibrational and thermodynamic properties of liquids within the soft potential model
Creators: name: Xu, Haichen
name: Baggioli, Matteo
name: Keyes, Tom
Publisher: name: arXiv
Year: 2023
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Contrary to the case of solids and gases, where Debye theory and kinetic theory offer a good description for most of the physical properties, a complete theoretical understanding of the vibrational and thermodynamic properties of liquids is still missing. Liquids exhibit a vibrational density of states (VDOS) which does not obey Debye law, and a heat capacity which decreases monotonically with temperature, rather than growing as in solids. Despite many attempts, a simple, complete and widely accepted theoretical framework able to formally derive the aforementioned properties has not been found yet. Here, we revisit one of the theoretical proposals, and in particular we re-analyze the properties of liquids within the soft-potential model, originally formulated for glasses. We confirm that, at least at a qualitative level, many characteristic properties of liquids can be rationalized within this model. We discuss the validity of several phenomenological expressions proposed in the literature for the density of unstable modes, and in particular for its temperature and frequency dependence. We discuss the role of negative curvature regions and unstable modes as fundamental ingredients to have a linear in frequency VDOS. Finally, we compute the heat capacity within the soft potential model for liquids and we show that it decreases with temperature, in agreement with experimental and simulation data.
description: revised manuscript matching the published version
The role of self-interacting right-handed neutrinos in galactic structure
Creators: name: Argüelles, C. R.
name: Mavromatos, N. E.
name: Rueda, J. A.
name: Ruffini, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It has been shown previously that the DM in galactic halos can be explained by a self-gravitating system of massive keV fermions (`inos') in thermodynamic equilibrium, and predicted the existence of a denser quantum core of inos towards the center of galaxies. In this article we show that the inclusion of self-interactions among the inos, modeled within a relativistic mean-field-theory approach, allows the quantum core to become massive and compact enough to explain the dynamics of the S-cluster stars closest to the Milky Way's galactic center. The application of this model to other galaxies such as large elliptical harboring massive central dark objects of $\sim 10^9 M_\odot$ is also investigated. We identify these interacting inos with sterile right-handed neutrinos pertaining to minimal extensions of the Standard Model, and calculate the corresponding total cross-section $σ$ within an electroweak-like formalism to be compared with other observationally inferred cross-section estimates. The coincidence of an ino mass range of few tens of keV derived here only from the galactic structure, with the range obtained independently from other astrophysical and cosmological constraints, points towards an important role of the right-handed neutrinos in the cosmic structure.
description: 33 pages, 9 figures, version to appear in JCAP
Five years of optical and infrared monitoring of Betelgeuse with the Himawari-8 meteorological satellite
Creators: name: Taniguchi, Daisuke
name: Yamazaki, Kazuya
name: Uno, Shinsuke
Publisher: name: Zenodo
Year: 2023
Subjects: stars: individual (Betelgeuse)
stars: massive
stars: mass-loss
dust, extinction
infrared: stars

description: Red supergiants are a class of massive stars, who will soon end their lives as supernovae. Time variability at this stage, such as pulsation and mass loss, gives close insights into several fields including massive star evolution and supernova light curves. As a laboratory of the time variability of red supergiants, we focus on the Great Dimming of Betelgeuse in early 2020, an unusual fall and rise in the optical brightness by ~1.2mag. Here we present 16-bands photometry of Betelgeuse in 0.45-13.5micron from January 2017 to today making use of the images taken by the Himawari-8 meteorological satellite. Analyzing these light curves, we show that two mechanisms, a decreased effective temperature and an enhanced dust extinction, may have both contributed to the Great Dimming by the same amounts. We also discuss the future ability of meteorological satellites for the time-domain investigation of other evolved stars.
description: {"references": ["Taniguchi, D. et al. (2022), Nature Astronomy, 6, 930", "Montarg\u00e8s, M. et al. (2021), Nature, 594, 365", "Harper, G. M. et al. (2020), ApJ, 905, 34", "Dupree, A. K. et al. (2020), ApJ, 899, 688", "Bessho, K. et al. (2016), JMeSJ, 94, 151"]}
Covid-19, Ebola, and HIV - Leveraging Lessons to Maximize Impact
Creators: name: Johnston, C.
name: Collier, A.
name: Celum, C.
name: Piot, P.
name: Holmes, K.K.
name: Cohen, M.S.
name: El‑Sadr, W.
name: Barnabas, R.
Publisher: name: Massachussetts Medical Society
Year: 2020

description: As researchers who have long experience with HIV/AIDS prevention, vaccines, and therapies, some of whom also have experience with Ebola, we believe it is critical to build the response to the Covid-19 pandemic on lessons from the HIV pandemic and recent Ebola outbreaks.
Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models
Creators: name: Robb, M.
name: Deming, M.E.
name: Michael, N.L.
name: Cohen, M.S.
name: Neuzil, K.M.
Publisher: name: Massachussetts Medical Society
Year: 2020

description: The third coronavirus outbreak in the past 20 years, the SARS-CoV-2 pandemic has caused unprecedented morbidity, mortality, and economic disruption. Safe, effective, and deployable SARS-CoV-2 vaccines are urgently needed to mitigate the consequences of the pandemic and protect from future outbreaks. The accelerated response to Covid-19 includes investments in preclinical and clinical testing and manufacture of multiple vaccine candidates, with efficacy trials in the United States anticipated to start in July 2020.
Curved $A_{\infty}$-algebras and gauge theory
Creators: name: Zahariev, Svetoslav
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We propose a general notion of algebraic gauge theory obtained via extracting the main properties of classical gauge theory. Building on a recent work on transferring curved $A_{\infty}$-structures we show that, under certain technical conditions, algebraic gauge theories can be transferred along chain contractions. Specializing to the case of the contraction from differential forms to cochains, we obtain a simplicial gauge theory on the matrix-valued simplicial cochains of a triangulated manifold. In particular, one obtains discrete notions of connection, curvature, gauge transformation and gauge invariant action.
description: Final version, to appear in Journal of Homotopy and Related Structures
Can Directionality of HIV Transmission be Predicted by Next-Generation Sequencing Data?
Creators: name: Kumarasamy, N.
name: Makhema, J.
name: Redd, A.D.
name: Quinn, T.C.
name: Chariyalertsak, S.
name: Grinsztejn, B.
name: Cohen, M.S.
name: McCauley, M.
name: Hakim, J.G.
name: Gamble, T.
name: Chen, Y.Q.
name: Eshleman, S.H.
name: Pilotto, J.H.
name: Porcella, S.F.
name: Hosseinipour, M.C.
name: Santos, B.R.
name: Kumwenda, J.
name: Mills, L.A.
name: Wilson, E.A.
name: Hudelson, S.E.
name: Hall, M.
name: Barbier, A.E.
name: Piwowar-Manning, E.
name: Rose, R.
name: Laeyendecker, O.
name: Lamers, S.
name: Fraser, C.
Publisher: name: Oxford University Press
Year: 2020

description: Background: We evaluated use of phylogenetic methods to predict the direction of human immunodeficiency virus (HIV) transmission. Methods: For 33 pairs of HIV-infected patients (hereafter, "index patients") and their partners who acquired genetically linked HIV infection during the study, samples were collected from partners and index patients close to the time when the partner seroconverted (hereafter, "SC samples"); for 31 pairs, samples collected from the index patient at an earlier time point (hereafter, "early index samples") were also available. Phylogenies were inferred using env next-generation sequences (1 tree per pair/subtype). The direction of transmission (DoT) predicted from each tree was classified as correct or incorrect on the basis of which sequences (those from the index patient or the partner) were closest to the root. DoT was also assessed using maximum parsimony to infer ancestral node states for 100 bootstrap trees. Results: DoT was predicted correctly for both single-pair and subtype-specific trees in 22 pairs (67%) by using SC samples and in 23 pairs (74%) by using early index samples. DoT was predicted incorrectly for 4 pairs (15%) by using SC or early index samples. In the bootstrap analysis, DoT was predicted correctly for 18 pairs (55%) by using SC samples and for 24 pairs (73%) by using early index samples. DoT was predicted incorrectly for 7 pairs (21%) by using SC samples and for 4 pairs (13%) by using early index samples. Conclusions: Phylogenetic methods based solely on the tree topology of HIV env sequences, particularly without consideration of phylogenetic uncertainty, may be insufficient for determining DoT.
Design, Implementation and Evaluation of an External Pose-Tracking System for Underwater Cameras
Creators: name: Winkel, Birger
name: Nakath, David
name: Woelk, Felix
name: Köser, Kevin
Publisher: name: arXiv
Year: 2023
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In order to advance underwater computer vision and robotics from lab environments and clear water scenarios to the deep dark ocean or murky coastal waters, representative benchmarks and realistic datasets with ground truth information are required. In particular, determining the camera pose is essential for many underwater robotic or photogrammetric applications and known ground truth is mandatory to evaluate the performance of e.g., simultaneous localization and mapping approaches in such extreme environments. This paper presents the conception, calibration and implementation of an external reference system for determining the underwater camera pose in real-time. The approach, based on an HTC Vive tracking system in air, calculates the underwater camera pose by fusing the poses of two controllers tracked above the water surface of a tank. It is shown that the mean deviation of this approach to an optical marker based reference in air is less than 3 mm and 0.3 deg. Finally, the usability of the system for underwater applications is demonstrated.
Stationary solutions to the Boltzmann equation in the Hydrodynamic limit
Creators: name: Esposito, Raffaele
name: Guo, Yan
name: Kim, Chanwoo
name: Marra, Rossana
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: Despite its conceptual and practical importance, the rigorous derivation of the steady incompressible Navier-Stokes-Fourier system from the Boltzmann theory has been {an} outstanding {open problem} for general domains in 3D. We settle this open question in {the} affirmative, in the presence of a small external field and a small boundary temperature variation for the diffuse boundary condition. We employ a recent quantitative $L^{2}-L^{\infty }$ approach with new $L^{6}$ estimates for the hydrodynamic part $\mathbf{P}f$ of the distribution function. Our results also imply the validity of Fourier law in the hydrodynamical limit, and our method {leads to {asymptotical} stability of steady Boltzmann solutions as well as the derivation of the {unsteady} Navier-Stokes Fourier system}.
description: New $L^6$ bound of the hydrodynamic part is added, which allows direct convergence to Navier-Stokes-Fourier system in Theorem 1.1 and Theorem 1.3
DPYD and TYMS polymorphisms as predictors of 5 fluorouracil toxicity in colorectal cancer patients
Creators: name: Khalij, Yassine
name: Belaid, Imtinen
name: Chouchane, Sana
name: Amor, Dorra
name: Omezzine, Asma
name: rejeb, Nabila Ben
name: Ahmed, Slim ben
name: Bouslama, Ali
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of cancer death. 5-Fluorouracil (5-FU) is an essential component of systemic chemotherapy for CRC. Our objective was to determine the genotypic frequency of polymorphisms affecting dihydropyrimidine dehydrogenase (DPYD) and thymidylate synthetase (TYMS) genes and to correlate the genetic profile with the toxicity due to 5-FU, also considering nongenetic factors. This is a prospective study that involved 66 patients. We extracted DNA by salting out methods. We carried out the genotyping of the different polymorphisms by simple PCR for the TYMS 5'UTR and by PCR-RFLP for DPYD: 1905 + 1 G > A, 85 T > C, 496 A > G, 1679 T > G, c.483 + 18G > A and the TYMS: 5'UTR VNTR, 5'UTR G > C and 3'UTR. The study of the association of DPYD and TYMS polymorphisms with the various signs of toxicity under 5-FU revealed that the polymorphisms 496 A > G were significantly associated with hepatotoxicity: OR = 3.85 (p = 0.04). In addition, 85 T > C was significantly associated with mucositis and neurotoxicity: OR = 4.35 (p = 0.03), OR = 3.79 (p = 0.02). For TYMS, the only significant association we observed for 5'UTR with vomiting: OR = 3.34 (p = 0.04). The incidence of adverse reactions related to 5-FU appears to be influenced in patients with CRC by the identified DPYD and TYMS gene polymorphisms in the Tunisian population.
MPEC 2024-R281 : 2024 RJ13
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 RJ13

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Elemental abundances of red supergiants measured with near-infrared high-resolution spectra
Creators: name: Taniguchi, Daisuke
name: Team, The WINERED
Publisher: name: Zenodo
Year: 2023
Subjects: stars: abundances
stars: massive
stars: late-type
infrared: stars
Galaxy: abundances
methods: data analysis

description: Red supergiants are a class of young, luminous stars with complicated spectra rich in molecular lines. However, their brightness makes them one of the excellent tracers for metallicity distribution in the Milky Way disk, and thus there is a demand for examining the systematic errors in the derived abundances of red supergiants in detail. To examine the systematics, we analyzed the near-infrared high-resolution spectra of ten nearby red supergiants observed with the WINERED spectrograph (0.97-1.32micron, R=28,000). As a result, we find that the metallicities of red supergiants determined in this work are in good agreement with well-established results of Cepheids. Therefore, our measurement method for red supergiants is as reliable as methods for Cepheids assuming that young stars (age<200Myr) in the Solar neighborhood have homogeneous elemental abundances, which are represented by those of gas.
description: {"references": ["Taniguchi, D. et al. (2021), MNRAS, 502, 4210", "Pagel, B. E. J. (1997), \"Nucleosynthesis and Chemical Evolution of Galaxies\"", "Ikeda, Y. et al. (2022), PASP, 134, 015004", "Matsunaga, N. et al. (2020), ApJS, 246, 10", "Coelho, P. et al. (2005), A&A, 443, 735", "Otsubo, S. et al. (2016), SPIE, 990879", "Ekstr\u00f6m, S. et al. (2012), A&A, 537, A146", "Luck, R. E. (2018), AJ, 156, 171", "Massey, P. et al. (2021), AJ, 79, 16"]}
Challenges of HIV diagnosis and management in the context of pre-exposure prophylaxis (PrEP), post-exposure prophylaxis (PEP), test and start and acute HIV infection: a scoping review
Creators: name: Brown, C.
name: Fidler, S.
name: Doherty, M.
name: Sanders, E.J.
name: Ndung'u, T.
name: Cohen, M.
name: Rutstein, S.E.
name: Ananworanich, J.
name: Patel, P.
name: Cairns, G.
name: Elliott, T.
Publisher: name: John Wiley and Sons Inc.
Year: 2019

description: Introduction: Knowledge of HIV status relies on accurate HIV testing, and is the first step towards access to HIV treatment and prevention programmes. Globally, HIV-status unawareness represents a significant challenge for achieving zero new HIV infections and deaths. In order to enhance knowledge of HIV status, the World Health Organisation (WHO) recommends a testing strategy that includes the use of HIV-specific antibody point-of-care tests (POCT). These POCTs do not detect acute HIV infection, the stage of disease when viral load is highest but HIV antibodies are undetectable. Complicating things further, in the presence of antiretroviral therapy (ART) for pre-exposure prophylaxis (PrEP) or post-exposure prophylaxis (PEP), other currently available testing technologies, such as viral load detection for diagnosis of acute HIV infection, may yield false-negative results. In this scoping review, we evaluate the evidence and discuss alternative HIV testing algorithms that may mitigate diagnostic dilemmas in the setting of increased utilization of ART for immediate treatment and prevention of HIV infection. Discussion: Missed acute HIV infection prevents people living with HIV (PLHIV) from accessing early treatment, increases likelihood of onward transmission, and allows for inappropriate initiation or continuation of PrEP, which may result in HIV drug resistance. While immediate ART is recommended for all PLHIV, studies have shown that starting ART in the setting of acute HIV infection may result in a delayed or complete absence of development of HIV-specific antibodies, posing a diagnostic challenge that is particularly pertinent to resource-limited, high HIV burden settings where HIV-antibody POCTs are standard of care. Similarly, ART used as PrEP or PEP may supress HIV RNA viral load, complicating current HIV testing algorithms in resource-wealthy settings where viral detection is included. As rollout of PrEP continues, HIV testing algorithms may need to be modified. Conclusions: With increasing use of PrEP and ART in acute infection we anticipate diagnostic challenges using currently available HIV testing strategies. Research and surveillance are needed to determine the most appropriate assays and optimal testing algorithms that are accurate, affordable and sustainable.
Systematic reviews and meta-analyses of prospective cohort studies and randomized controlled trials of fructose-containing sugars and cardiometabolic outcomes
Creators: name: Khan, Tauseef
name: Sievenpiper, John
Publisher: name: figshare
Year: 2022
Subjects: subject: 111104 Public Nutrition Intervention
subject: FOS: Health sciences

description: List of systematic reviews and meta-analyses of prospective cohort studies and randomized controlled trials of fructose-containing sugars and cardiometabolic outcomes
Large deviations and exact asymptotics for constrained exponential random graphs
Creators: name: Yin, Mei
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We present a technique for approximating generic normalization constants subject to constraints. The method is then applied to derive the exact asymptotics for the conditional normalization constant of constrained exponential random graphs.
description: 14 pages
Paddelia eichhorniae Panesar 2004
Creators: name: Pešić, Vladimir
name: Chatterjee, Tapas
name: Bordoloi, Sabitry
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Limnesiidae
Paddelia
Paddelia eichhorniae

description: Paddelia eichhorniae Panesar, 2004
Records from the study area: Uttar Pradesh—Panesar (2004).
Habitat: Pond with lotus and the water hyacinth (Eichhornia crassipes).
Distribution: India.
description: Published as part of Pešić, Vladimir, Chatterjee, Tapas & Bordoloi, Sabitry, 2010, A checklist of the water mites (Acari: Hydrachnidia) of India, with new records and description of one new species, pp. 1-54 in Zootaxa 2617 (1) on page 10, DOI: 10.11646/zootaxa.2617.1.1, http://zenodo.org/record/197964
title: Ανάπτυξη ενός πολυκριτήριου ευφυούς συστήματος αποφάσεων για υποστήριξη της λήψης ομαδικών αποφάσεων μεγάλης κλίμακας σε καταστάσεις έκτακτης ανάγκης
title: Development of a multi-criteria intelligent decision system, to support large-scale group decision making in emergency situations
Creators: name: Φραγκοπουλος Δημητριος
Publisher: name: Technical University of Crete
Year: 2024

description: Η διαδικασία λήψης αποφάσεων που ακολουθείται σε επίπεδο ομάδων, σε εταιρείες και οργανισμούς, έχει κινήσει το ενδιαφέρον από πολλούς τομείς, μεταξύ αυτόν της επιχειρησιακής έρευνας και των ευφυών συστημάτων.
Η παρούσα διπλωματική επικεντρώνεται στην υποστήριξη της λήψης ομαδικών αποφάσεων, όπου το μέγεθος της ομάδας και κατά συνέπεια τα διαφορετικά είδη αποφασιζόντων μέσα σε αυτήν, κάνουν τη σύγκλιση σε μία κοινώς αποδεκτή απόφαση δύσκολη.
Σύμφωνα με τα παραπάνω επιλέχθηκε η προσέγγιση του προβλήματος με μεθόδους πολυκριτήριας ανάλυσης αποφάσεων (MCDA) και συγκεκριμένα θα γίνει χρήση μεθόδων από τις οικογένειες UTA και TOPSIS. Επίσης, θα γίνει εφαρμογή τεχνικών εξόρυξης στις αναλύσεις τόσο μεγάλου όγκου δεδομένων από το διαδίκτυο όσο και για τη δημιουργία ομάδων/συστάδων.
Η υλοποίηση του κώδικα θα γίνει με τη γλώσσα προγραμματισμού Python. Επιπλέον, θα αναπτυχθεί γραφικό περιβάλλον διεπαφής προκειμένου να είναι δυνατή η χρήση του για εκπαιδευτικούς και πειραματικούς σκοπούς.
Απώτερος σκοπός είναι το σύστημα να αυξάνει την πληροφόρηση των αποφασιζόντων σχετικά με τις προτιμήσεις του καθενός και με τη δυνατότητα ανάδρασης, να οδηγεί στη σύνθεση μίας κοινώς αποδεκτής βέλτιστης λύσης, η οποία ταυτόχρονα θα μεγιστοποιεί την ικανοποίηση των αποφασιζόντων.
description: The decision-making process of groups, in corporation and organization, has been studied by many scientific fields, including the field of operational research combined with the development of intelligent systems.
The scope of this thesis is to propose and apply a methodology for supporting large-scale group decision-making in emergency situations, where the group consists of decision makers from many different backgrounds, making the convergence under time pressure on a commonly accepted solution a challenge.
For these reasons, the proposed methodology approaches the problem with multicriteria analysis methods, specifically incorporating the UTA and TOPSIS family of methods. Furthermore, datamining techniques and clustering/classification of data will be used, to support the extraction of big data from many sources, such as the web.
The system will be developed using one of the latest versions of the python programming language. Furthermore, a graphical user interface will be added, to increase the ease of use and accessibility of such systems, for research and educational purposes.
The system aims to achieve each goal, by increasing the amount of useful information exchanged by the decision makers, by informing them about each other’s preference model through an interactive feedback process. The final goal of this iterative process is to achieve a type of convergence of the decision makers preference, to find a satisfactory alternative of acceptance.
Sexually transmitted infections and HIV in the era of antiretroviral treatment and prevention: the biologic basis for epidemiologic synergy
Creators: name: Chen, J.S.
name: Council, O.D.
name: Cohen, M.S.
Publisher: name: John Wiley and Sons Inc.
Year: 2019

description: Introduction: HIV is a unique sexually transmitted infection (STI) that is greatly affected by other concomitant “classical” bacterial and viral STIs that cause genital ulcers and/or mucosal inflammation. STIs also serve as a marker for risky sexual behaviours. STIs increase infectiousness of people living with HIV by increasing the viral concentration in the genital tract, and by increasing the potential for HIV acquisition in people at risk for HIV. In addition, some STIs can increase blood HIV concentration and promote progression of disease. This review is designed to investigate the complex relationship between HIV and classical STIs. Discussion: Treatment of STIs with appropriate antibiotics reduces HIV in blood, semen and female genital secretions. However, community-based trials could not reliably reduce the spread of HIV by mass treatment of STIs. Introduction of antiretroviral agents for the treatment and prevention of HIV has led to renewed interest in the complex relationship between STIs and HIV. Antiretroviral treatment (ART) reduces the infectiousness of HIV and virtually eliminates the transmission of HIV in spite of concomitant or acquired STIs. However, while ART interrupts HIV transmission, it does not stop intermittent shedding of HIV in genital secretions. Such shedding of HIV is increased by STIs, although the viral copies are not likely replication competent or infectious. Pre-exposure prophylaxis (PrEP) of HIV with the combination of tenofovir disoproxil fumarate and emtricitabine (TDF/FTC) prevents HIV acquisition in spite of concomitant STIs. Conclusions: STIs remain pandemic, and the availability of ART may have led to an increase in STIs, as fear of HIV has diminished. Classical STIs present a huge worldwide health burden that cannot be separated from HIV, and they deserve far more attention than they currently receive.
Broadcasting of Quantum Correlations: Possibilities & Impossibilities
Creators: name: Chatterjee, Sourav
name: Sazim, Sk
name: Chakrabarty, Indranil
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work, we extensively study the problem of broadcasting of quantum correlations. This includes broadcasting of quantum entanglement as well as correlations that go beyond the notion of entanglement. It is quite well known from the "No-Broadcasting theorem" that perfect broadcasting of quantum correlation is not possible. However it does not rule out the possibility of partial broadcasting of correlations where we can get lesser correlated states from a given correlated state. In order to have a holistic view of broadcasting, we investigate this problem by starting with most general representation of two qubit mixed states in terms of the Bloch vectors. As a cloning transformation we have used universal symmetric optimal Buzek-Hillery (B-H) cloner both locally and nonlocally. More specifically, we obtain a set of ranges in terms of Bloch vectors for which broadcasting of entanglement will be possible. In addition to the idea of broadcasting of entanglement for general two qubit mixed states, we explore broadcasting of quantum correlations that go beyond entanglement with the help of both local and nonlocal cloners. Remarkably, we find that it is impossible to even partially broadcast such correlations by using both local and nonlocal quantum copying machines. Taking two different types Buzek-Hillery quantum cloners (state dependent and state independent) we analytically prove the impossibility of even partial broadcasting of correlation. Lastly, we generalize this impossibility result for any symmetric or asymmetric cloning machines as well. This result brings out a fundamental difference between the correlation defined from the perspective of entanglement and the correlation measure which claims to go beyond entanglement.
description: 18 pages, 6 figures, 6 tables. arXiv admin note: text overlap with arXiv:quant-ph/0607067 by other authors. Accepted in Physical Review A
Digital Twins of Business Processes as Enablers for IT / OT Integration
Creators: name: Waclawek, Hannes
name: Schäfer, Georg
name: Binder, Christoph
name: Hirsch, Eduard
name: Huber, Stefan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: The vision of Industry 4.0 introduces new requirements to Operational Technology (OT) systems. Solutions for these requirements already exist in the Information Technology (IT) world, however, due to the different characteristics of both worlds, these solutions often cannot be directly used in the world of OT. We therefore propose an Industrial Business Process Twin (IBPT), allowing to apply methods of one world to another not directly but, instead, to a representation, that is in bidirectional exchange with the other world. The proposed IBPT entity acts as an intermediary, decoupling the worlds of IT and OT, thus allowing for an integration of IT and OT components of different manufacturers and platforms. Using this approach, we demonstrate the four essential Industry 4.0 design principles information transparency, technical assistance, interconnection and decentralized decisions based on the gamified Industry 4.0 scenario of playing the game of Nine Men's Morris. This scenario serves well for agent based Artificial Intelligence (AI)-research and education. We develop an Open Platform Communications Unified Architecture (OPC UA) information and communication model and then evaluate the IBPT component with respect to the different views of the Reference Architecture Model Industry 4.0 (RAMI4.0).
description: Submitted to INDIN2023 conference
title: Бухгалтерское дело (продвинутый курс)
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный технический университет имени Ю.А. Гагарина, ЭБС АСВ
Year: 2023

description: Учебно-методическое пособие содержит множество ситуационных задач, отражающих хозяйственно-финансовую деятельность предприятий и организаций с учетом требований нормативных документов. Решение этих задач позволяет освоить процесс последовательного выполнения всех процедур работы бухгалтера: заполнение первичных документов, составление бухгалтерских проводок, ведение учетных регистров. Образцы необходимых форм первичных документов и учетных регистров помещены в учебном пособии – это позволяет ускорить процесс решения задач и повышает качество обучения. Учебно-методическое пособие подготовлено в соответствии с требованиями Федерального государственного образовательного стандарта (ФГОС) третьего поколения и предназначено для студентов, обучающихся по направлению подготовки 38.04.01 «Экономика» (профиль «Бухгалтерский учет, контроль налогообложения и судебно-бухгалтерская экспертиза»).
On a Ramsey-type problem of Erdős and Pach
Creators: name: Kang, Ross J.
name: Long, Eoin
name: Patel, Viresh
name: Regts, Guus
Publisher: name: arXiv
Year: 2014
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C55 (Primary), 05D10, 05D40 (Secondary)

description: In this paper we show that there exists a constant $C>0$ such that for any graph $G$ on $Ck\ln k$ vertices either $G$ or its complement $\bar{G}$ has an induced subgraph on $k$ vertices with minimum degree at least $\frac12(k-1)$. This affirmatively answers a question of Erdős and Pach from 1983.
description: 9 pages; in 2nd version, Eoin Long has been added as co-author and the main result is improved by a log k factor
Differential Extracellular, but Similar Intracellular, Disposition of two Tenofovir Formulations in the Male Genital Tract
Creators: name: Nelson, J.A.E.
name: Chen, J.
name: Gay, C.L.
name: Maas, B.M.
name: Dumond, J.B.
name: Kashuba, A.D.M.
name: Sykes, C.
name: Greene, S.A.
name: Cohen, M.S.
name: Schauer, A.P.
name: Prince, H.M.A.
name: Blake, K.H.
Publisher: name: International Medical Press Ltd
Year: 2019

description: Background: The male genital tract (MGT) is a viral sanctuary and likely HIV reservoir; understanding MGT pharmacokinet-ics (PK) of antiretrovirals (ARVs) used for curative strategies is critical to eradication and cure. Tenofovir alafenamide (TAF) is a tenofovir (TFV) formulation designed to maximize efficacy/minimize toxicity with unknown MGT PK. Methods: HIV-positive and HIV-negative men receiving TFV-based regimens provided six paired blood plasma (BP) and semen samples. Extracellular (TFV, TAF, emtricitabine [FTC]) drug concentrations in BP and seminal plasma (SP), and intracellular metabolite (IM) and endogenous nucleotide (EN) concentrations were measured in peripheral blood mononuclear cells (PBMCs) and seminal mononuclear cells (SMCs). Exposure ratios for SP:BP, SMC:PBMC and IM:EN were calculated from PK parameters generated by noncompartmental analysis. HIV viral load was measured in BP and SP. Results: Sixteen HIV-positive (n=8, TDF/FTC; n=8, TAF/FTC) and eight HIV-negative (TDF/FTC) men provided samples. Median TFV SP:BP ratios differed between TDF and TAF (1.5 versus 7.4), due to lower TFV BP concentrations with TAF coupled with TFV SP concentrations similar to TDF. FTC SP:BP ratios were approximately 3. SMC concentrations of IMs and ENs were a fraction of PBMC concentrations (1–22%), though IM:EN ratios exceed a suggested protective threshold. Conclusions: TAF SP PK was unexpected. IM SMC concentrations were low relative to PBMC, as were EN concentrations, suggesting differences in cell phenotype and lineage in the MGT; these differences in phenotype and pharmacology may have an impact on selecting and dosing ARVs used in cure strategies.
title: Компьютерное моделирование технологических процессов и систем
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный технический университет имени Ю.А. Гагарина, ЭБС АСВ
Year: 2023

description: Рассмотрены основы моделирования технологических процессов и систем, включающие техническое, математическое и программное обеспечение процедур анализа и синтеза проектных решений. Изложены общие подходы к построению математических моделей сложных технологических систем. Рассмотрены вопросы автоматизации конструирования и технологической подготовки производства. Приведены примеры моделирования в среде MATLAB. Для студентов направлений 15.03.05, 15.04.02, 15.03.02 при изучении курсов «Компьютерные программы для проектирования объектов машиностроения», «Компьютерные технологии при проектировании технологического оборудования», «Компьютерное моделирование процессов формообразования изделий».
Unitary thermodynamics from thermodynamic geometry II: Fit to a local density approximation
Creators: name: Ruppeiner, George
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Strongly interacting Fermi gasses at low density possess universal thermodynamic properties which have recently seen very precise $PVT$ measurements by a group at MIT. This group determined local thermodynamic properties of a system of ultra cold $^6\mbox{Li}$ atoms tuned to Feshbach resonance. In this paper, I analyze the MIT data with a thermodynamic theory of unitary thermodynamics based on ideas from critical phenomena. This theory was introduced in the first paper of this sequence, and characterizes the scaled thermodynamics by the entropy per particle $z= S/N k_B$, and energy per particle $Y(z)$, in units of the Fermi energy. $Y(z)$ is in two segments, separated by a second-order phase transition at $z=z_c$: a "normal" segment for $z>z_c$, and a "superfluid" segment for $z
description: 30 pages, 7 figures, 25 references
MotionBEV: Attention-Aware Online LiDAR Moving Object Segmentation with Bird's Eye View based Appearance and Motion Features
Creators: name: Zhou, Bo
name: Xie, Jiapeng
name: Pan, Yan
name: Wu, Jiajie
name: Lu, Chuanzhao
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Identifying moving objects is an essential capability for autonomous systems, as it provides critical information for pose estimation, navigation, collision avoidance, and static map construction. In this paper, we present MotionBEV, a fast and accurate framework for LiDAR moving object segmentation, which segments moving objects with appearance and motion features in the bird's eye view (BEV) domain. Our approach converts 3D LiDAR scans into a 2D polar BEV representation to improve computational efficiency. Specifically, we learn appearance features with a simplified PointNet and compute motion features through the height differences of consecutive frames of point clouds projected onto vertical columns in the polar BEV coordinate system. We employ a dual-branch network bridged by the Appearance-Motion Co-attention Module (AMCM) to adaptively fuse the spatio-temporal information from appearance and motion features. Our approach achieves state-of-the-art performance on the SemanticKITTI-MOS benchmark. Furthermore, to demonstrate the practical effectiveness of our method, we provide a LiDAR-MOS dataset recorded by a solid-state LiDAR, which features non-repetitive scanning patterns and a small field of view.
CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation.
Creators: name: O'sullivan, Paul A
name: Aidarova, Aigerim
name: Afonina, Inna S
name: Manils, Joan
name: Thurston, Teresa LM
name: Instrell, Rachel
name: Howell, Michael
name: Boeing, Stefan
name: Ranawana, Sashini
name: Herpels, Melanie
name: Chetien, Riwia
name: Bassa, Matilda
name: Flynn, Helen
name: Frith, David
name: Snijders, Ambrosius P
name: Howes, Ashleigh
name: Beyaert, Rudi
name: Bowcock, Anne M
name: Ley, Steven C
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Tumour Biology
subject: Tumour Biology
classificationCode: Chemical Biology & High Throughput
subject: Chemical Biology & High Throughput
classificationCode: Gene Expression
subject: Gene Expression
classificationCode: Immunology
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: Genetics & Genomics
subject: Genetics & Genomics
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology
classificationCode: Genome Integrity & Repair
subject: Genome Integrity & Repair
classificationCode: Biochemistry & Proteomics
subject: Biochemistry & Proteomics

description: Rare mutations in CARD14 promote psoriasis by inducing CARD14-BCL10-MALT1 complexes that activate NF-kB and MAP kinases. Here, the downstream signalling mechanism of the highly penetrant CARD14E138Aalteration is described. In addition to BCL10 and MALT1, CARD14E138A associated with several proteins important in innate immune signalling. Interactions with M1-specific ubiquitin E3 ligase HOIP, and K63-specific ubiquitin E3 ligase TRAF6 promoted BCL10 ubiquitination and were essential for NF-kB and MAP kinase activation. In contrast, the ubiquitin binding proteins A20 and ABIN1, both genetically associated with psoriasis development, negatively regulated signalling by inducing CARD14E138A turnover. CARD14E138A localized to early endosomes and was associated with the AP2 adaptor complex. AP2 function was required for CARD14E138A activation of mTOR complex 1, which stimulated keratinocyte metabolism, but not for NF-kB nor MAP kinase activation. Furthermore, rapamycin ameliorated CARD14E138A-induced keratinocyte proliferation and epidermal acanthosis in mice, suggesting that blocking mTORC1 may be therapeutically beneficial in CARD14-dependent psoriasis.
title: Математический анализ
Creators: name: ELS IPR BOOKS
Publisher: name: Саратовский государственный технический университет имени Ю.А. Гагарина, ЭБС АСВ
Year: 2023

description: В учебном пособии приведены необходимые теоретические сведения, графические иллюстрации, примеры решения типовых задач, задания для контрольных работ, список рекомендуемой литературы. Пособие может быть рекомендовано студентам направлений 38.03.01, 38.05.01 и др. всех форм обучения.