cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Identification and molecular characterization of a putative heme ABC transporter in Neisseria meningitidis
Creators: name: Ingrey, Keely
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biology, Microbiology.

description: A detailed mechanism for heme uptake in pathogenic Neisseriae has not yet been elucidated. Once heme is deposited in the periplasmic space, a heme dedicated ABC transporter has been hypothesized to convey heme into the cytoplasm. To address this hypothesis, we used several molecular techniques to identify and characterize a putative heme ABC transporter in Neisseria meningitidis. Using 2-D gel electrophoresis, we identified six proteins with increasing expression under heme-limiting conditions. Although these proteins appear to be iron-regulated, the genes encoding these proteins are not associated with periplasmic components of ABC transporters. Using DNA microarray analysis, we identified eleven ABC transporter components. A mutation in one of these genes, the ATPase NMB1993, was constructed. No difference in the ability of various iron sources to support the growth of the mutant and wild-type strains was observed under iron-restrictive conditions. No difference in growth rates between the two strains was discerned, suggesting no role in heme metabolism. Another uncharacterized putative periplasmic component, NMB0586, exhibited 27% amino acid identity to a recently characterized periplasmic heme-binding protein in the Haemophilus ducreyi transporter. To address its role in heme metabolism, NMB0586 was disrupted by insertional inactivation. The ability of various iron sources to support the growth of the mutant and wild-type strains was compared under iron-restrictive conditions. The mutant failed to display a heme-deficient phenotype. However, in view of the recognized degenerate binding specificity of the permease component of some ABC transporters, the heme-binding property of NMB0586 was studied. Purified NMB0586 bound to heme at a concentration of 10-4 M, using enhanced chemiluminescence. Furthermore, the binding of purified NMB0586 protein to hemin-agarose demonstrated concentration dependent binding. However, increasing concentrations of competing heme ligand did not result in a decrease in NMB0586 protein binding to hemin-agarose. NMB0586 was also unable to functionally complement a heme-deficient mutant of Escherichia coli. These findings suggest that NMB0586 is unlikely involved in heme acquisition in meningococci. In conclusion, this study describes the difficulties in identifying a meningococcal heme ABC transporter, but highlights several techniques for the future identification and characterization of a heme ABC transporter in Neisseriae.
Injury prevention intervention strategies among Aboriginal peoples : A systematic review of literature and preliminary report of Aboriginal injury prevention programs in BC
Creators: name: Olsen, Lise
name: Smith, Dorry
name: Turcotte, Kate
name: Pike, Ian, 1958-
Publisher: name: The University of British Columbia
Year: 2021

description: This report is a systematic review of the literature, and preliminary report of the Aboriginal Injury Prevention Programs in BC
Regionalwahlen in Südkorea 2018
Creators: name: Mosler, Hannes B.
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: The paper analyzes the 2018 local elections in South Korea. It starts off by explaining the country’s election system, which besides separate presidential and general elections also features local ones too. After discussing the evolution of the local election system since its introduction in 1987, and the political background to its somewhat late fully fledged realization in the middle of the 1990s, the paper continues by explaining details of the various offices that are elected at two different regional levels. After briefly describing central aspects of the given voting rights, and discussing the characteristics and current developments of political parties, the text then turns to the analysis of the election results. In the beginning, basic parameters are given – such as voter turnout rate as well as the overall distribution of votes – in a historical comparison, pointing out in the process the landslide victory of the government party of the newly (May 2017) elected liberal president Moon Jae-in. This is followed by a discussion of participation by and outcomes for female candidates in the election. Finally, the results of the simultaneously held by-elections and the reelection of twelve National Assembly members are explained and put into context. The third section of the paper addresses the reasons behind the observed outcomes, in particular against the backdrop of the last two rightist-conservative governments and the new liberal one too. The paper is summed up by a conclusion that takes a brief look into the near future, and tries to make sense of the regional elections' results — in particular regarding the Moon-administration’s likely subsequent performance, as well as forecasts for the upcoming general elections in 2020.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 148 (2018): ASIEN (Juli)
Deutschlands Politik gegenüber der Belt and Road Initiative der Volksrepublik China 2013–2018
Creators: name: Harnisch, Sebastian
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: The article describes and explains Germany’s societal, economic, and political reactions to the “Belt and Road Initiative” (BRI). This is (potentially) China’s global interconnectivity platform, established in 2013 to address development challenges in some of the country’s border provinces, in its export-led growth model, as well as the infrastructure and development gaps in neighboring regions. Applying a liberal theory perspective, the article finds strong economic support for the initiative in Germany but also growing political concerns about regulatory conflicts over equal market access, Chinese investments in the European Union, and their (potential) political implications for intra-EU decision-making processes. The article concludes that some structural conflicts between the EU/Germany and China are inevitable, as evidenced by the recent launch of the EU’s own infrastructure initiative for Asia – but also that several structural adjustments as well as dwindling Chinese resources will mitigate these conflicts in the future.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 148 (2018): ASIEN (Juli)
Efficient blind speech signal separation using independent component analysis
Creators: name: Pan, Qiongfeng
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Engineering, Electronics and Electrical.

description: Blind speech signal separation has a wide range of potential applications in our life, such as speech enhancement for speech recognition, teleconference application, hearing aids etc. The ultimate aim of blind speech signal separation is to mimic the action of a human in a cocktail party situation, where our hearing system can focus on any specific audio source of interest while suppressing all other sources present even in noisy environments. Blind source separation (BSS) provides a good tool to approach this problem. In blind source separation, source signals are estimated using only information observed at receivers and the estimation is performed blindly, without information on source signals and the mixing system. In this thesis, we concentrate on issues of relevance to convolutive blind speech signal separation based on the general frame work of Independent Component Analysis (ICA). Both time and frequency domain convolutive BSS algorithms are investigated in our thesis. First we conduct our convolutive speech signal separation in the frequency domain. We propose a convolutive blind signal separation approach for joint speech signal separation and echo cancellation. Then, we suggest a simple means to using the psychoacoustic properties of human auditory system to improve the quality of separated speech signals. Next, we propose to combine convolutive blind source separation with beamforming to deal with speech separation in heavy reverberation acoustic environment. By exploiting spatial information from beamforming, we maintain the speech separation performance with lower computational complexity. Because of the inherent problems in frequency domain BSS algorithms, we investigate novel algorithms to improve the convergence and reduce the complexity of time domain convolutive BSS algorithm. We propose the application of MMax partial update algorithm to the time domain convolutive BSS (MMax BSS) to demonstrate that the partial update scheme applied in the MMax LMS algorithm for single channel can be extended to multichannel time domain convolutive BSS with little deterioration in performance and possible computational complexity saving. Also we propose exclusive maximum selective-tap time domain convolutive BSS algorithm (XMax BSS) that reduces the interchannel coherence of the tap-input vectors and improves the conditioning of the autocorrelation matrix resulting in improved convergence rate and reduced misalignment. Moreover, the computational complexity is reduced since only half tap inputs are selected for updating.
Erstlese- und Schreiblehrgang: Leseschlau
Creators: name: Rickli, Ursula
Publisher: name: Lehrmittelverlag Kanton Solothurn
Year: 2010
Subjects: subject: 370 - Erziehung, Schul- und Bildungswesen

description: Das Lese- und Schreiblehrmittel "Leseschlau" setzt auf eine intensive Lautschulung. Am Anfang des Lehrgangs stehen die Sprechbewegungsbilder, welche die Mundstellungen der verschiedenen Sprechlaute darstellen und so den Kindern ein Bewusstsein der eigenen Sprechbewegung vermitteln. Das didaktische "Erfolgsgeheimnis" liegt in der festen Verankerung der Buchstaben in der gesprochenen Sprache. Das Lehrwerk umfasst folgende Teile: Handbuch / Lauttafeln - Lesekarten / Anlautbilder / Anlauttabelle / Koiervorlagen Band A und B / Lesetexte - Auswahl 1 und 2 und 3 / Werkstätten und Arbeitspläne - Auswahl 1 und 2 und 3 / Schreibheft - Steinschrift und Basisschrift / Lesehefte Serie A und B und C / CD-ROM / DVD Film (unter www.leseschlau.ch)
D4.2 – Personalised health modelling and predictions II
Creators: name: Giorgos Giotis
name: Thanos Kalligeris
name: Konstantina Liagkou
name: Spyros Papafragkos
name: Maritini Kalogerini
name: Kenneth Muir
name: Ke Te-Min
name: Artitaya Lophatananon
Publisher: name: Zenodo
Year: 2024
Subjects: Personalized Health
AI Models
Risk Prediction
Health Data
Knowledge Management
Clinical AI

description: This document summarizes the actions performed under T4.1 - “Personalized Health Modelling and Predictions” in the context of WP4 “Knowledge Management and Modelling in the iHelp Platform” at this phase of the project. The first version of this series of deliverables, i.e., D4.1 - “Personalised health modelling and predictions I”, provided an extended description of the mechanisms and Artificial Intelligence (AI) models that will be implemented for the realisation of personalised health and risk prediction models. The implementation of the ΑΙ algorithms that are being created during the project’s lifecycle highly depend on the provided datasets on which they are trained. At the previous phase of the project, the description of the datasets that are going to be used, drove the actions under this Task towards a concrete description and specification of the AI algorithms and models that will be utilized.

In this updated version D4.2 - “Personalised health modelling and predictions II”, the primary data were available for two out of five pilots -namely UNIMAN and MUP- and a sample dataset was provided by the FPG pilot. In this respect, an initial approach of the development of the AI models and some preliminary results are provided in the corresponding sub-sections of Section 6. As in the previous version, this document encapsulates the necessary and relevant information that was researched from recent bibliography to facilitate the manipulation of the available datasets, setting the basis for the design and implementation of the models. Finally, in this deliverable are analysed the main concepts behind the models, also in compliance with an analysis of the importance of known and unknown risk factors based on the description of the clinical/primary data.
6. Duisburg-Frankfurt Workshop „Institutionen in der Entwicklung Ostasiens“
Creators: name: Pascha, Werner
name: Storz, Cornelia
name: Taube, Markus
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 148 (2018): ASIEN (Juli)
ПУТИ СНИЖЕНИЯ СЕБЕСТОИМОСТИ ПРОДУКЦИИ В УСЛОВИЯХ ЦИФРОВОЙ ЭКОНОМИКИ
Creators: name: Cафаров, Бахтиёр
name: Кадирова, Зулхумор
Publisher: name: Zenodo
Year: 2024

description: Рассмотрены основные способы, предпринимаемые предприятиями, по снижению себестоимости продукции. Данные способы помогают производственному предприятию снижать себестоимость выпускаемой продукции.
Die kleine Prinzessin und…
Creators: name: Amstad, Sabine
Publisher: name: Gamma Druck + Verlag
Year: 1998
Subjects: subject: Ästhetische Bildung in der Eingangsstufe
subject: 370 - Erziehung, Schul- und Bildungswesen

description: ein Märchen in Bild und Wort
Evaluating the media as a source of Drug Therapy Information
Creators: name: Therapeutics Initiative (University Of British Columbia)
Publisher: name: The University of British Columbia
Year: 2023

description: Therapeutics Letter 67 discusses the role played by the media as a source of drug therapy information. Conclusions: The media are important for disseminating new therapeutic information and hence quality and completeness of reporting is vital. Frequently therapeutic effects are neither as spectacular nor as disastrous as media headlines suggest. Health care professionals must know how to critique and verify information coming from news stories.
4. Brühler Tagung junger Ostasien-Experten: '’Differenzierungsprozesse in Asien: Politik, Wirtschaft, Kultur"
Creators: name: Findeisen, Genia
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 84 (2002): ASIEN (Juli)
Mit Sockenpuppen unterwegs. Bashkë me kukullat çorape
Creators: name: Amstad, Sabine
name: Lubos, Christiane
name: Schuh, Claudia
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2013
Subjects: subject: Interkulturalität
subject: Interkulturelles Figurenspiel
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Interkulturelles Figurenspiel ist pädagogische Handlung, kreativer Akt und Medium der transkulturellen Verständigung. Nach achtjähriger Zusammenarbeit zwischen Studierenden und Lehrenden im Partnerschaftsprojekt Nord-Süd der Pädagogischen Hochschule FHNW und der Universität Luigj Gurakuqi ist die vorliegende Publikation entstanden, ein Arbeits- und Sachbuch in einem. Es dokumentiert die Erfahrungen während zweier Workshops, in denen ein Figurenspiel mit Sockenpuppen erarbeitet wurde.
Slovakia from the downfall of Communism to its accession into the European Union, 1989-2004: The re-emergence of political parties and democratic institutions
Creators: name: Hocman, Juraj
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: History, European.
subject: Political Science, General.

description: Throughout the 1990s, several observers of the post-communist transformation in East Central Europe viewed the Slovaks as a non-historic nation hastily modernized during the communist era. Since it had been mostly invisible in Austria-Hungary and Czechoslovakia, Slovak history appeared as ruptured and fragmented. Following the fall of the communist regime and the creation of the independent Slovak Republic, the country's image was primarily associated with radical nationalism, intolerance towards its minorities and an unstable domestic political scene. These were seen as major reasons for the detour in Slovakia's transformation to democracy in the mid-1990s. In the 2000s, western scholars re-examined the earlier interpretations of Slovak history that had stressed the compliance of Slovak society with Communism and its missing tradition in the state and institution-building processes. They came to the conclusion that stereotypes in the interpretations of Slovakia's transformation in the 1990s stemmed from unfamiliarity with the facts and preconceived methodological approaches. This dissertation examines Slovakia's evolution from the downfall of Communism (1989) to the accession of the independent Slovak Republic (1993) into the European Union (2004) from a broader historical perspective. It challenges the assumptions of political inexperience and passivity of Slovak society as major hindrances in the more recent phase of its evolution. It argues that the building of the Slovak political nation had started in Austria-Hungary and continued in Czechoslovakia under all its regimes. As a result, Slovak political parties and institutions as the main carriers of democratic transformation did not emerge in the early 1990s in a political and institutional vacuum. After the creation of the independent Slovak Republic, the focus of Slovak political elites switched from national emancipation to integration with the ED. In the 1998 parliamentary elections, the political parties in opposition, supported by the nongovernmental sector and western democracies, defeated an illiberal regime ruling over Slovakia. In spite of the alleged historical deficits of Slovak society, this change was seen by many as a result of its sudden awakening. This dissertation suggests that Slovakia's transformation from a post-communist state to a democratic one, marked by the country's accession into the ED, can be better understood as a continuation of the processes that had begun in the mid-1960s, rather than as a result of the change of government in 1998.
L'utilisation de l'echelle de Hare (PCL-R) chez les professionnels du Service correctionnel du Canada: Analyse preliminaire du recours au diagnostic de psychopathie dans le parcours institutionnel des delinquants
Creators: name: Bourgouin, Frederic
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Sociology, Criminology and Penology.

description: L'objectif de cette recherche est double. Dans un premier temps, nous tenions a identifier la maniere dont les psychologues du Service correctionnel du Canada (SCC) emploient l'echelle de psychopathie de Hare-Revisee (PCL-R) dans leur pratique evaluative. Dans un second temps, nous voulions explorer la question de l'impact du diagnostic de psychopathie sur les pratiques correctionnelle. D'ailleurs, nous avions comme premices de recherche que la production d'un diagnostic de psychopathie affecterait defavorablement la trajectoire correctionnelle du delinquant. Le cadre theorique retenu s'inspire librement des travaux de Michel Foucault sur le dispositif disciplinaire. Au niveau methodologique, nous avons mene des entrevues aupres de 7 psychologues du Centre regional de reception. Le contenu des entretiens fut ensuite analyse en vue d'extraire et d'organiser les themes dominants. Les resultats de notre analyse demontrent que le score obtenu a la PCL-R est principalement utilise comme facteur de risque statique significatif dans l'evaluation du risque global. Le score est aussi utilise a des fins taxinomiques, mais de facon secondaire. Par ailleurs, les resultats demontrent que le fait de presenter un profil de la psychopathie ne determinerait pas directement le type de pratiques correctionnelles mais susciterait plutot la vigilance des acteurs impliques clans le processus decisionnel quant a des considerations relatives au placement, au traitement et a la mise en liberation, voire aussi le maintien en incarceration. Le niveau de risque global ainsi que le type de comportement adopte en etablissement determineraient davantage la logique correctionnelle adoptee par le dispositif qu'une qualification dans la psychopathie en soi. Dans ces circonstances, il semblerait donc que le SCC tend a diluer de sa substance therapeutique et valoriserait davantage une logique de prise en charge proche de la doctrine de la nouvelle penologie.
Comment: Stability and Commercial Information
Creators: name: Schüller, Margot
Publisher: name: Asien
Year: 2021

description: China's transition to a market economy is accompanied by an unprecedented economic growth. However, due to structural problems the economic dynamism seems to have been running out of steam since the late 1990s. In its recent report "China in the World Economy. The Domestic Policy Challenges", the OECD attributes the structural problems to a lack of integration in factor markets, among business segments, and among regions. The OECD report is comprised of an impressive number of sector studies and analyses of economy-wide issues. It is based on the commonly available set of Chinese government data without questioning whether we can rely on this official version of reality. In contrast, the question of the quality of official information has been frequently picked up in many press reports and by a number of economists over the past years.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Role of hedgehog signaling in branching morphogenesis and patterning of the fin ray during zebrafish fin regeneration
Creators: name: Zhang, Jing
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Biology, Molecular.

description: Zebrafish have the capability to regenerate their fins after injury. Previous studies from our laboratory showed that fin regeneration triggers the re-expression of genes involved in the hedgehog (hh) signaling pathway. One member of the hh family, sonic hedgehog (shh) was suggested to regulate bone patterning based on its expgression pattern and functional analysis. Another member of the hh family, Indian hedgehog (ihha) is expressed in the differentiating scleroblasts, the bone-matrix releasing cells, of each fin ray, and may have a more direct role on bone formation based on its expression pattern and known function in other vertebrates. The present study is aimed at investigating the role of hh signalling in patterning the fin ray regenerate and more specifically its role in ray branching morphogenesis. In a first approach, we used the zebrafish 2.2shh:gfp:ABC transgenic line, in which GFP expression recapitulates the endogenous expression of shh, to ablate the shh-expressing cells using a laser beam. Results show that such ablation leads to a delay of ray bifurcation suggesting that the shh-expressing cells play an important role in branching morphogenesis. In a second approach, we cloned the zebrafish hedgehog interacting protein (hip), a hedgehog antagonist, to investigate the effects of its overexpression on ray patterning. Analysis of hip expression during fin regeneration suggests its involvement in limiting hh signaling on the lateral sides of the dermal bones and in their medial region during branching morphogenesis. Overexpression of hip via in vivo cell transfection in the regenerating fin causes a branching delay, possibly as a result of the altered expression of patched1, the hh receptor and type X collagen, a component of the fin ray. These results suggest that hh signaling is involved in patterning the ray branching during zebrafish fin regeneration. Based on the distinct role of shh and ihha suggested by studies in other systems, ihha may be more involved in the scleroblast proliferation and differentiation, and shh is likely to be responsible to pattern the bone formation by directing the site of scleroblast differentiation or possibly mediating scleroblast migration.
Stability and Commercial Information - An Economic Approach and a Look at China
Creators: name: Fischer, Doris
Publisher: name: Asien
Year: 2021

description: Stability and information are prominent topics of economic research. Unfortunately though, research concerning the influence of the information system on economic and social stability is scarce. In contrast, Chinese politics argue with the importance of social and economic stability to limit freedom in information flows. The article summarizes theoretical attempts in economic research to grasp questions concerning the relationship between stability, information, and economic performance, thus describing a new research programme. The central thesis is that analysing institutions and institutional change within the Chinese information system might be the best starting point to explain the impact of the information system on economic performance and stability.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Fibrinogen decreases cardiomyocyte contractility through an ICAM-1-dependent mechanism
Creators: name: Boyd, John H.
name: Chau, Edmond H.
name: Tokunanga, Chiho
name: Bateman, Ryon M.
name: Haljan, Greg
name: Davani, Ehsan Y.
name: Wang, Yinjin
name: Walley, Keith R. (Keith Robert)
Publisher: name: BioMed Central
Year: 2016

description: Introduction: Cardiomyocytes exposed to inflammatory processes express intracellular adhesion molecule-1 (ICAM-1). We investigated whether fibrinogen and fibrinogen degradation products, including D-dimer, could alter cardiomyocyte contractile function through interaction with ICAM-1 found on inflamed cardiomyocytes. Methods: In vivo, rats were injected with endotoxin to model systemic inflammation, whereas isolated rat cardiomyocytes were treated with tumor necrosis factor-alpha to model the inflammatory environment seen following exposure to bacterial products such as lipopolysaccharide. Results: In vivo, endotoxin administration profoundly decreased cardiac contractile function associated with a large increase in intracardiac ICAM-1 and perivascular fibrinogen. Confocal microscopy with double-staining of isolated rat cardiomyocytes demonstrated colocalization of ICAM-1 and fibrinogen. This interaction was disrupted through pre-treatment of the cells with an ICAM-1-blocking antibody. Functionally, isolated rat cardiomyocyte preparations exhibited decreased fractional shortening when incubated with fibrinogen, and through the use of synthetic peptides, we determined that residues 117–133 of the fibrinogen gamma chain are responsible for this interaction with ICAM-1. Despite having crosslinked gamma chains, D-dimer retained the ability to decrease cardiomyocyte contractility. Conclusion: Site 117–133 of the fibrinogen gamma chain is able to depress cardiomyocyte contractility through binding ICAM-1.
Comment: Stability in Instability
Creators: name: Opper, Sonja
Publisher: name: Asien
Year: 2021

description: The astonishingly rapid economic development of China's Township Village Enterprises (TVEs) has been a focus of research in economics and economic sociology for more than a decade. A review of the literature however, does not leave one with the impression that the issue has been exhaustively explored. Even more important is the pervasive feeling that important lessons can be taken from TVE-development in China, which have not yet been fully grasped, nor have possible repercussions of standard property rights theory been systematically developed.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Short Term Synaptic Plasticity Across Multiple Electrosensory Maps in the Weakly Electric Fish Apteronotus leptorhynchus
Creators: name: Mileva, Gerri
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Biology, Molecular.
subject: Biology, Neuroscience.

description: The electrosensory lateral line lobe (ELL) is the first order electrosensory processing station in the brain of the electric fish Apteronotus leptorhynchus, and is the only nucleus to receive input from electroreceptors on the skin. The ELL is subdivided into three maps: the centromedial segment (CMS), centrolateral segment (CLS), and lateral segment (LS) which receive input from tuberous electroreceptors processing high frequency signals. Two feedback pathways from higher order nuclei, the nucleus praemenintialis (nP) and the eminentia posterior granularis (EGp) are integral to processing in the ELL and show synaptic plasticity on various time scales. This thesis focuses on characterizing short term plasticity (STP) in nP-ELL synapses between the CMS, CLS and LS, and the development of an in vitro slice containing the entire direct feedback pathway. We find that LS pyramidal cells show greater facilitation in response to high frequency stimulation of direct feedback fibres as compared to CMS.
Stability in Instability - China’s TVEs and the Evolution of Property Rights
Creators: name: Taube, Markus
Publisher: name: Asien
Year: 2021

description: For two decades economic and social stability in China's rural areas has been based on the successful evolution of township village enterprises. These enterprises, however, feature property rights structures which according to conventional property rights theory should make these enterprises highly inefficient and prone to quick dissolution. But as closer analysis indicates, exactly these ambiguous property rights structures may be the recipe for success. They constitute highly flexible best practice solutions for corporate survival in the context of rapidly changing environments in a transition economy. But as the Chinese market economy matures, these ambiguous property rights structures will nevertheless have to make way for clearly defined — stable — property rights structures. The paper introduces some hypotheses concerning the forces underlying these evolutionary processes.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
OMIP: A 35-marker imaging mass cytometry panel for the co-detection of HIV and immune cell populations in human formalin fixed paraffin embedded intestinal tissue
Creators: name: Hu, Kevin
Publisher: name: Zenodo
Year: 2024
Subjects: imaging mass cytometry
human FFPE tissue
spatial biology
cell segmentation

description: Here we provide the original IMC images, segmentation model, intensity measurement pipeline and scripts used to create the main figure of our manuscript.

 

OMIP Abstract

We introduce a 35-marker imaging mass cytometry (IMC) panel for a detailed examination of immune cell populations and HIV RNA in formalin fixed paraffin embedded (FFPE) human intestinal tissue. The panel has broad cell type coverage and particularly excels in delineating subsets of mononuclear phagocytes and T cells. Markers for key tissue structures are included, enabling identification of epithelium, blood vessels, lymphatics, and musculature. The described method for HIV RNA detection can be generalized to other low abundance RNA targets, whether endogenous or pathogen derived. As such, the panel presented here is useful for high parameter spatial mapping of intestinal immune cells and their interactions with pathogens such as HIV.
Comment: Stability Through More Participation?
Creators: name: Li, Lianjiang
Publisher: name: Asien
Year: 2021

description: Given China's huge population and its growing importance in the world, any political reform that may affect its long-term stability and its possible transition to democracy deserves the scrutiny of political scientists. The introduction of direct election in Chinese villages is one of such reforms. As Dr. Schubert points out, Chinese leaders seem to expect that this limited democratic reform will help improve governance and enhance stability in rural China, where over 70 percent of 1.3 billion Chinese reside. In addition, some reform-minded senior leaders also seem to expect that grassroots democracy may provide democratic training to the vast peasant population. In reality, of course, no reform only produces intended consequences.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Online Banking Frauds – An Overview
Creators: name: DR.A. DHARMENDRAN
Publisher: name: Zenodo
Year: 2020

description: Online Banking Fraud is a fraud or theft committed using online technology to illegally remove money from a bank account and/or transfer money to an account in a different bank. Online Banking Fraud is a form of identity theft and is usually made possible through techniques such as phishing. Now online banking is widely used to check account details, make purchases, pay bills, transfer funds, print statements etc. Generally, the user identity is the customer identity number and password is provided to secure transactions. But due to some ignorance or silly mistakes you can easily fall into the trap of cyber criminals.
Stability through more participation?
Creators: name: Schubert, Gunter
Publisher: name: Asien
Year: 2021

description: The article brings into focus an ongoing research project on village elections in the PRC. Introduced in the late 1980s, they have undergone almost fifteen years of implementation. However, China scholars have started only in. recent years to concentrate on village elections more systematically and to analyse their impact on Communist rule in the countryside. The empirical findings so far present a very contradictory picture, suggesting both more and less stability through the direct ballot. Also, much research has been done on electoral quality and participation patterns, while qualitative studies dealing with changes in the peasants' political awareness and behaviour lag somewhat behind. The project introduced here examines the peasant's political culture in six villages situated in three provinces, trying to narrow the mentioned gap within contemporary research on local democracy in the PRC.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Musical theatre in translation: A semiotic analysis of Jacques Brel's "L'Homme de la Mancha"
Creators: name: Hubsch, Jean-Frederic
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2006
Subjects: subject: Literature, Romance.
subject: Music.
subject: Theater.
subject: Literature, American.
subject: Language, General.

description: Translation of musical theatre has been afforded little academic study. This project aims to help fill this gap in order to develop the study of musical theatre in translation studies. This begins with defining the specificity of musical theatre as a form, using prior work in both the study and translation of theatre and of opera. The goal is to position musical theatre as an object for analysis and to outline the constraints attached to the translation thereof. An analysis of the effect on translation of some of these constraints follows based on notions from discourse analysis and music interpretation. Finally, this semiotic framework focussing on the use of isotopy is applied to a specific case of musical theatre translation, that of Man of La Mancha translated into French by Jacques Brel as L'homme de La Mancha.
Comment: The institutional roots of the Japanese construction state
Creators: name: Broadbent, Jeffrey
Publisher: name: Asien
Year: 2021

description: The project by Thomas Feldhoff and his associates addresses a basic puzzle of the contemporary Japanese political-economy - why, despite so many wounds to the public good, does the nation's massive public works budget continue unabated? As their core hypothesis, the Feldhoff team proposes that Japan's "construction state" (doken kokka) is largely responsible for this morass. A construction state can be defined as a government which puts much more public investment into the construction of public works than can be realistically justified by public need. In their project, Feldhoff team proposes to investigate the composition and inner dynamics of Japan's "construction state" and its effects upon public policy and sustainability.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Recent advances in asthma genetics
Creators: name: Zhang, Jian
name: Paré, Peter D
name: Sandford, Andrew J
Publisher: name: BioMed Central
Year: 2016

description: There are over 100 genes that have been reported to be associated with asthma or related phenotypes. In 2006–2007 alone there were 53 novel candidate gene associations reported in the literature. Replication of genetic associations and demonstration of a functional mechanism for the associated variants are needed to confirm an asthma susceptibility gene. For most of the candidate genes there is little functional information. In a previous review by Hoffjan et al. published in 2003, functional information was reported for 40 polymorphisms and here we list another 22 genes which have such data. Some important genes such as filaggrin, interleukin-13, interleukin-17 and the cysteinyl leukotriene receptor-1 which not only were replicated by independent association studies but also have functional data are reviewed in this article.
Japan’s Construction Lobby Activities - Systemic Stability and Sustainable Regional Development
Creators: name: Feldhoff, Thomas
Publisher: name: Asien
Year: 2021

description: The term "construction state" has been used, to refer to a system of vested interests in construction activities that embraced Japan at different geographical levels of scale. A system of collusion between politicians, bureaucrats, and businessmen evolved and led to massive government spending on public works projects. Its pace and scope have resulted in fiscal crisis and environmental devastation and have aroused the opposition of local residents. This paper will analyze the construction-related networks of relationships of the central actors in the so-called "iron triangle" ofpolitics, bureaucracy and construction business, and its influence on regional development. We shall theorize that sustainability will remain an unattainable ideal in regional development as long as the stability of the "construction state" is preserved by certain formal and informal elements in Japan's politicoeconomic system. These elements, however, have until now remained comparatively stable, despite of some reform initiatives.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Supplementary figures and tables from Towards acoustic monitoring of bees: wingbeat sounds are related to species and individual traits
Creators: name: Ballesteros, Alberto Rodríguez
name: Desjonquères, Camille
name: Hevia, Violeta
name: Llorente, Marina García
name: Ulloa, Juan Sebastián
name: Llusia Genique, Diego
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310399
subject: Ecology not elsewhere classified
classificationCode: 310901
subject: Animal behaviour

description: Global pollinator decline urgently requires effective methods to assess their trends, distribution and behaviour. Passive acoustics is a non-invasive and cost-efficient monitoring tool increasingly employed for monitoring animal communities. However, insect sounds remain highly unexplored, hindering the application of this technique for pollinators. To overcome this shortfall and support future developments, we recorded and characterized wingbeat sounds of a variety of Iberian domestic and wild bees and tested their relationship with taxonomic, morphological, behavioural and environmental traits at inter- and intra-specific levels. Using directional microphones and machine learning, we shed light on the acoustic signature of bee wingbeat sounds and their potential to be used for species identification and monitoring. Our results revealed that frequency of wingbeat sounds is negatively related with body size and environmental temperature (between-species analysis), while positively related with experimentally induced stress conditions (within-individual analysis). We also found a characteristic acoustic signature in the European honeybee that supported automated classification of this bee from a pool of wild bees, paving the way for passive acoustic monitoring of pollinators. Overall, these findings confirm that insect sounds during flight activity can provide insights on individual and species traits, and hence suggest novel and promising applications for this endangered animal group.This article is part of the theme issue ‘Towards a global toolkit for insect biodiversity monitoring’.
Comment: Stability and Change: Typifying ’Atypical’ Employment in Japan
Creators: name: Gottfried, Heidi
Publisher: name: Asien
Year: 2021

description: The restructuring of work is proceeding rapidly through a series of reforms and economic transformations that promise to alter both the industrial structure and the mix of employment arrangements. Comparative studies on the regulation of labour markets, employment policy and industrial relations have not adequately understood these changes despite an otherwise sophisticated development of theories and data on post-Fordism and employment regimes (e.g., Crouch and Streeck 1997). Thus, for example, the School of Comparative Political Economy (Kitschelt, Lange, Marks and Stephens, 1999) generally refers to work and social regulations designed for standard industrial work and a corresponding form of standard family life, underestimating the weight of the service sector economy in advanced capitalistic countries. Due to this 'industrialism bias', the heterogeneity in content of work, modes of work organization, ways of working, and gender employment structures within the service sector tend to be blind spots.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Development of pan-specific antibody against trimethyllysine for protein research
Creators: name: Liang, Ziqian
name: Wong, Ronald P
name: Li, Lin H
name: Jiang, Hesheng
name: Xiao, Hao
name: Li, Gang
Publisher: name: BioMed Central
Year: 2015

description: Background: Trimethylation of the Nε-lysine residues in a protein is one of the most important events of posttranslational modifications. Simple methods for rapid detection and isolation of the Nε-trimethylated protein species are needed. This report introduces a novel method to prepare the affinity purified antibody specific for the Nε-trimethylated lysine (tMeK). The applications of the purified antibody are also reported in this paper. Methods We generated the methylated keyhole limpet heomocyanin (KLH) under controlled chemical methylation reaction using CH3I and used it as an immunogen to raise anti-methylated lysine antibodies. The tMeK specific antibody was selectively isolated using a two-step affinity chromatography in which the mMeK/dMeK specific antibodies were removed and the tMeK specific antibody was captured. Finally, the eluted anti-tMeK antibody was characterized. Results The ELISA results indicated that the antibody reacted only to tMeK but not to mono- and dimethyllysine. Western-blot results showed that the Nε-trimethylated proteins were detected in both animal tissue and cultured cells and that the antibody signal could be competitively inhibited with free tMeK. Conclusion The specific tMeK antibody we developed is useful for one-step isolation of proteins with Nε-trimethyllysine residues and also for the detection, identification and localization of proteins with trimethyllysine residues in the cells.
Stability and Change in Japanese Employment Institutions
Creators: name: A. Shire, Karen
Publisher: name: Asien
Year: 2021

description: The expansion of temporary employment, more than any other recent employment change, has been credited with unraveling long-term employment commitments in the U.S. This paper raises the question of whether a major recent deregulation of temporary employment in Japan can be expected to have similar effects. Within neo-institutionalist research, debates about the effects of liberalisation on institutional continuity and change tend to focus on the persistence of traditional arrangements, ignoring developments in new sectors and new forms of employment. In this paper we approach the issue of the future of long-term employment from the perspective of the recent development of temporary work. While the deregulation of this employment form is too recent to assess its effects, we expect that a new strata of “permanent temporary” employees will eventually impact on long-term employment practices. In the meantime however, old inequalities, based in the gendered segmentation of employment, seem to be re-cast in the form of temporary labor.
description: Asien, Nr. 84 (2002): ASIEN (Juli)
Service-Learning mit Fokus Nachhaltigkeit (SeLeN)
Creators: name: Bänninger, Christine
name: Gysin, Stefanie Hilda
name: Isler-Wirth, Patrick
name: Künzli, Christine
Publisher: name: oekom
Year: 2014
Subjects: subject: 370 - Erziehung, Schul- und Bildungswesen

description: Im theoretisch-konzeptionellen Beitrag wird eine Möglichkeit diskutiert, wie die Bereiche Bildung für eine nachhaltige Entwicklung und nachhaltige Entwicklung in der Gemeinde im Kontext formaler Bildung aufeinander bezogen werden können und welche Synergien zwischen diesen Bereichen bestehen: Das als Grundlage eines Entwicklungs- und Forschungsprojekts erarbeitete Konzept «Service-Learning mit Fokus Nachhaltigkeit» (SeLeN) das im Zentrum dieses Beitrages steht wird theoretisch hergeleitet und begründet.
Das Konzept «Service-Learning mit Fokus Nachhaltigkeit» (SeLeN) - eine Bereicherung für den Sachunterricht?
Creators: name: Bänninger, Christine
name: Gysin, Stefanie Hilda
name: Isler-Wirth, Patrick
name: Künzli, Christine
Publisher: name: Klinkhardt
Year: 2014
Subjects: subject: 370 - Erziehung, Schul- und Bildungswesen

description: Die Relevanz des Konzepts «Service-Learning mit Fokus Nachhaltigkeit» (SeLeN) für den perspektivenintegrierenden Sachunterricht wird diskutiert. Dazu werden die konstituierenden Elemente des Konzepts beschrieben und es wird der Frage nachgegangen, wie SeLeN in den Sachunterricht integriert werden kann.
title: Standardized patients in psychotherapy training and clinical supervision
title: study protocol for a randomized controlled trial
titleType: Subtitle
Creators: name: Kühne, Franziska
name: Heinze, Peter Eric
name: Weck, Florian
Publisher: name: Universität Potsdam
Year: 2020

description: Background Psychotherapy is highly effective and widely acknowledged for treating various mental disorders. Nevertheless, in terms of methods for teaching effective psychotherapeutic approaches and competencies, there has been a lack of investigation. Training and supervision are the main strategies for teaching therapist competencies, and standardized role-plays with simulated patients (i.e., trained individuals playing someone with a mental disorder) seem useful for evaluating training approaches. In medical education, this procedure is now internationally established. However, so far, little use has been made of standardized role-playing to evaluate training and supervision in the area of clinical psychology and psychotherapy. Methods In this study, standardized role-plays are used to evaluate methods for training and supervision. Central cognitive behavioral approaches for treating depression are taught in the training. The first experiment compares an active training approach (i.e., model learning) with a passive one (i.e., reading manual-based instructions). The second experiment compares a direct supervision technique (i.e., supervision based on video analysis) with an indirect one (i.e., supervision based on verbal reporting). In each experiment, 68 bachelor’s and master’s students of psychology will be randomly assigned to the experimental and control groups. Each student takes part in three role-plays (baseline, post and 3-month follow-up), which are all videotaped. Two independent raters assess therapist competencies in each role-play on the basis of a standardized competence scale. Discussion The research project aims to contribute to the development of specific training and supervision methods in order to improve psychotherapy training and patient care.
description: Postprints der Universität Potsdam : Humanwissenschaftliche Reihe, 628
Comment: Towards a Portrait of Multilingualism of Tokyo
Creators: name: V. Neustupný, Jiri
Publisher: name: Asien
Year: 2021

description: I believe that we live in a world of post-modernity, and that this world is governed by two opposing principles. One of them, which revealed itself early, is humanism. The other is rationalism (Neustupny 2000).
description: Asien, Nr. 84 (2002): ASIEN (Juli)