cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pharmacokinetics of intravenous ketorolac in cats undergoing gonadectomy
Creators: name: R Villa
name: G Ravasio
name: C Ferraresi
name: A Zonca
name: S Carli
name: L Borghi
name: P Cagnardi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Cell Biology
subject: Biochemistry

description: AIM: To determine the pharmacokinetics of ketorolac tromethamine (0.5 mg/kg) when administered I/V to cats undergoing gonadectomy.METHODS: Ketorolac was administered to nine female and three male shorthair domestic cats as an I/V bolus of 0.5 mg/kg after intubation, and 20 minutes prior to ovariectomy or orchiectomy. Intra-operative cardiorespiratory variables were monitored and blood samples were collected over 24 hours. Concentrations of ketorolac in serum were determined by high-performance liquid chromatography to establish pharmacokinetic parameters.RESULTS: During surgery, mean end tidal isoflurane concentration was 1.63 (SD 0.24)% and normocapnia and spontaneous ventilation were maintained in all animals. The kinetics of ketorolac was described by a two-compartment model. The distribution and elimination half-lives were 0.09 (SD 0.06) and 4.14 (SD 1.18) hours, respectively. The body clearance was 56.8 (SD 33.1) mL/h/kg. The volume of distribution at steady-state and the mean residence time were 323.9 (SD 115.7) mL/kg and 6.47 (SD 2.86) hours, respectively.CONCLUSION AND CLINICAL RELEVANCE: On the basis of the results, concentrations of ketorolac in serum in cats were above the human effective concentrations for 5–6 hours postoperatively. However, other studies including a control group are advocated to further investigate the ketorolac kinetics and the analgesic efficacy in this species.
BioSQL Reloaded: 1.0 Release, PhyloDB Module, and Future Features
Creators: name: Lapp, Hilmar
name: Holland, Richard
name: Mackey, Aaron
name: Piel, William H.
name: Schreiber, Mark
Publisher: name: figshare
Year: 2015
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences
subject: 60102 Bioinformatics
subject: Computer Software

description: Abstract for presentation at the 2008 Bioinformatics Open Source Conference (BOSC), held July 18-19 in Toronto, ON, Canada.
Additional file 2 of Alpine ecology, plant biodiversity and photosynthetic performance of marker plants in a nitrogen gradient induced by Alnus bushes
Creators: name: Kaltrina, Rexha
name: Kristi, Bego
name: Zyruku Dea
name: Shuka Lulezim
name: Husi René
name: Schneller Jakob
name: Reinhard, Bachofen
Publisher: name: figshare
Year: 2020
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 2: Table S2. Statistical proof of significance (p-values after Mann–Whitney, MaxStat-Lite, 3.60), 5 measurements per site b-1 to b-5.
Genotyping of Bulgarian Vitis vinifera L. cultivars by microsatellite analysis
Creators: name: Hvarleva, T.
name: Rusanov, K.
name: Lefort, F.
name: Tsvetkov, I.
name: Atanassov, A.
name: Atanassov, I.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: A characterization of the Bulgarian grapevine genepool (Vitis vinifera L. cultivars) was initiated through microsatellite analysis. Seventy four wine and table grapevine varieties from the National List of Cultivars, were analyzed at 9 microsatellite loci: VVS2, ssrVvUCH11, ssrVvUCH 29, ssrVrZAG21, ssrVrZAG47, ssrVrZAG62, ssrVrZAG64, ssrVrZAG79 and ssrVrZAG83. The high genetic diversity (78 %) allowed accurate identification and discrimination of the cultivars. The low PI value (1.201 x 10-8) reflects the high discriminative power of the chosen set of markers for the investigated population. Based on the microsatellite allele data, two pairs of old native varieties, Misket Cherven and Misket Vrachanski; Tamyanka and Tamyanka tvarda, were considered distinct cultivars. The synonymy of • Tamyanka, Italian Moscato Bianco and Greek Moschato Kerkyras and • Pamid and Greek Pamidi was verified, while the putative synonymy of Mavrud and Greek Mavroudi Arachovis was rejected. Further utilization of microsatellite profiling in the management of the Bulgarian grapevine genepool is discussed.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Mannose and xylose cannot be used as selectable agents for Vitis vinifera L. transformation
Creators: name: Kieffer, F.
name: Triouleyre, C.
name: Bertsch, C.
name: Farine, S.
name: Leva, Y.
name: Walter, B.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Only a few selectable marker systems for genetic engineering of grapevine have been studied in the past and only resistance to antibiotics has been used to recover transgenic vines. Since the acceptance of antibiotic resistances is small mannose and xylose were evaluated as selectable agents for the genetic transformation of grapevine. Survival of suspension cells and the ability to develop embryos from embryogenic calli were estimated in the presence of mannose and xylose. Embryogenic calli obtained from anther cultures of Vitis vinifera cv. Chardonnay were able to grow and to produce embryos even if mannose or xylose were the only source of carbohydrates.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Changes in the contents of micro- and trace-elements in wine due to winemaking treatments
Creators: name: Nicolini, G.
name: Larcher, R.
name: Pangrazzi, P.
name: Bontempo, L.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Forty-four mineral elements quantified by ICP-OES and ICP-MS were measured in wines, (a) after wine fining, at three pH levels with 10 different bentonites (1 g·l-1), (b) after addition of yeast hulls from 2 suppliers to wine (180 and 360 mg·1-1). Bentonite fining resulted in statistically significant increases of the large majority of elements, but in significant lower levels of Cu, K, Rb and Zn. The addition of yeast hulls caused a statistically significant depletion of the contents of Ce, Cu, Fe, La, Sb, U, V and Y.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Effects of bearing unit, spur or cane, on yield components and bud productivity
Creators: name: López-Miranda, S.
name: Yuste, J.
name: Lissarrague, J. R.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Research Note
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Factors influencing mortality, fecundity and fertility of grape phylloxera (Daktulosphaira vitifoliae Fitch)
Creators: name: Makee, H.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Research Note
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Effect of Vaporizer Temperature on Ambient Non-Refractory Submicron Aerosol Composition and Mass Spectra Measured by the Aerosol Mass Spectrometer
Creators: name: Docherty, Kenneth S.
name: Lewandowski, Michael
name: Jimenez, Jose L.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Biochemistry

description: Aerodyne Aerosol Mass Spectrometers (AMS) are routinely operated with a constant vaporizer temperature (Tvap) of 600°C in order to facilitate quantitative detection of non-refractory submicron (NR-PM1) species. By analogy with other thermal desorption instruments, systematically varying Tvap may provide additional information regarding NR-PM1 chemical composition and relative volatility, and was explored during two ambient studies. The performance of the AMS generally and the functional integrity of the vaporizer were not negatively impacted during vaporizer temperature cycling (VTC) periods. NR-PM1 species signals change substantially as Tvap decreases with that change being consistent with previous relative volatility measurements: large decreases in lower volatility components (e.g., sulfate, organic aerosol [OA]) with little, if any, decrease in higher volatility components (e.g., nitrate, ammonium) as Tvap decreases. At Tvap < 600°C, slower evaporation was observed as a shift in particle time-of-flight distributions and an increase in “particle beam blocked” (background) concentrations. Some chemically reduced (i.e., CxHy+) OA ions at higher m/z are enhanced at lower Tvap, indicating that this method may improve the analysis of some chemically reduced OA systems. The OA spectra changes dramatically with Tvap; however, the observed trends cannot easily be interpreted to derive volatility information. Reducing Tvap increases the relative O:C and CO2+, contrary to what is expected from measured volatility. This is interpreted as continuing decomposition of low volatility species that decreases more slowly (as Tvap decreases) than does the evaporation of reduced species. The reactive vaporizer surface and the inability to reach Tvap much below 200°C of the standard AMS limit the ability of this method to study the volatility of oxidized OA species.Copyright 2015 American Association for Aerosol Research
Grupo de Pesquisa GEPPEN da UFCSPA - Análise do clima de segurança no centro cirúrgico no período pré-pandêmico e pandêmico da COVID-19: métodos mistos
Creators: name: Ferreira, Rosilene Alves
name: Fassarella, Cintia Silva
Publisher: name: Zenodo
Year: 2023

description: Apresentação sobre métodos mistos para o grupo de pesquisa GEPPEN.
Towards ubiquitous OWL computing: Simplifying programmatic authoring of and querying with OWL axioms
Creators: name: Lapp, Hilmar
name: Balhoff, James P.
Publisher: name: figshare
Year: 2015
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Computer Software

description: Abstract for presentation at the 2014 Bioinformatics Open Source Conference (BOSC), held July 11-12 in Boston, MA.
PhyloCommons: Sharing, Annotating and Reusing Phylogenies
Creators: name: Lapp, Hilmar
name: Morris, Benjamin
Publisher: name: figshare
Year: 2015
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences
subject: 60102 Bioinformatics
subject: Computer Software

description: Abstract for presentation at the 2013 Bioinformatics Open Source Conference (BOSC), held July 19-20 in Berlin, Germany.
Effect of Vaporizer Temperature on Ambient Non-Refractory Submicron Aerosol Composition and Mass Spectra Measured by the Aerosol Mass Spectrometer
Creators: name: Docherty, Kenneth S.
name: Lewandowski, Michael
name: Jimenez, Jose L.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Biochemistry

description: Aerodyne Aerosol Mass Spectrometers (AMS) are routinely operated with a constant vaporizer temperature (Tvap) of 600°C in order to facilitate quantitative detection of non-refractory submicron (NR-PM1) species. By analogy with other thermal desorption instruments, systematically varying Tvap may provide additional information regarding NR-PM1 chemical composition and relative volatility, and was explored during two ambient studies. The performance of the AMS generally and the functional integrity of the vaporizer were not negatively impacted during vaporizer temperature cycling (VTC) periods. NR-PM1 species signals change substantially as Tvap decreases with that change being consistent with previous relative volatility measurements: large decreases in lower volatility components (e.g., sulfate, organic aerosol (OA)) with little, if any, decrease in higher volatility components (e.g., nitrate, ammonium) as Tvap decreases. At Tvap<600°C, slower evaporation was observed as a shift in particle time-of-flight distributions and an increase in “particle beam blocked” (background) concentrations. Some chemically-reduced (i.e., CxHy+) OA ions at higher m/z are enhanced at lower Tvap, indicating that this method may improve the analysis of some chemically reduced OA systems. The OA spectra changes dramatically with Tvap, however the observed trends cannot easily be interpreted to derive volatility information. Reducing Tvap increases the relative O:C and CO2+, contrary to what is expected from measured volatility. This is interpreted as continuing decomposition of low volatility species that decreases more slowly (as Tvap decreases) than does the evaporation of reduced species. The reactive vaporizer surface and the inability to reach Tvap much below 200°C of the standard AMS limit the ability of this method to study the volatility of oxidized OA species.
title: Joint determination of slip and stress drop in a Bayesian inversion approach:
title: a case study for the 2010 M8.8 Maule earthquake
titleType: Subtitle
Creators: name: Wang, Lifeng
name: Zöller, Gert
name: Hainzl, Sebastian
Publisher: name: Universität Potsdam
Year: 2020

description: Stress drop is a key factor in earthquake mechanics and engineering seismology. However, stress drop calculations based on fault slip can be significantly biased, particularly due to subjectively determined smoothing conditions in the traditional least-square slip inversion. In this study, we introduce a mechanically constrained Bayesian approach to simultaneously invert for fault slip and stress drop based on geodetic measurements. A Gaussian distribution for stress drop is implemented in the inversion as a prior. We have done several synthetic tests to evaluate the stability and reliability of the inversion approach, considering different fault discretization, fault geometries, utilized datasets, and variability of the slip direction, respectively. We finally apply the approach to the 2010 M8.8 Maule earthquake and invert for the coseismic slip and stress drop simultaneously. Two fault geometries from the literature are tested. Our results indicate that the derived slip models based on both fault geometries are similar, showing major slip north of the hypocenter and relatively weak slip in the south, as indicated in the slip models of other studies. The derived mean stress drop is 5-6 MPa, which is close to the stress drop of similar to 7 MPa that was independently determined according to force balance in this region Luttrell et al. (J Geophys Res, 2011). These findings indicate that stress drop values can be consistently extracted from geodetic data.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 888
Irrigation, nitrogen, and rootstock effects on volume loss of berries from potted Shiraz vines
Creators: name: Rogiers, S. Y.
name: Hatfield, J. M.
name: Keller, M.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Shiraz (synonym Syrah) berry volume increases in two phases and this may be followed by shrinkage during the later stages of ripening. Irrigation regime, nitrogen application rate and rootstock were tested for their effects on the onset of volume loss and extent of volume loss. Maximum berry volume correlated well with volume of berries at 35 d after flowering, the end of the cell division phase. Post-maximum berry shrinkage was not as severe of vines grown with split-root irrigation as compared with standard irrigation. However, these berries were smaller at harvest due to less pre-veraison expansion. Berries grown on vines with standard irrigation had greater post-maximum volume loss than those berries grown in a deficit irrigation treatment. Despite this, maximum berry volume correlated well with final volume in all treatments. N application rate had an effect on the onset of post-veraison expansion but not on the amplitude of maximum berry volume or final berry volume. Deficit irrigation delayed the onset of volume loss by 11 d. Rootstock also had an effect on the onset of volume loss with berries from vines grafted on the rootstock 101-14 Mgt losing volume 7 d earlier than berries from vines grafted on Ramsey. These results suggest that onset and degree of volume loss in Shiraz is sensitive to external influences.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Effects of water deficit stress on leaf and berry ABA and berry ripening in Chardonnay grapevines (Vitis vinifera)
Creators: name: Okamoto, G.
name: Kuwamura, T.
name: Hirano, K.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Chardonnay vines planted in root zone restricting beds were subjected to water deficit stress by withholding irrigation for a period starting at 15 (early stress; ES) or 25 d (late stress; LS) after veraison and lasting until harvest. Control vines were provided with normal irrigation. Both ES and LS treatments significantly decreased leaf water potential and caused leaf wilting 2 d after the start of each treatment. ABA levels in fruit zone leaves increased significantly 4 and 5 d after the onset of LS and ES treatments, respectively. After 2 d of ES treatment, the berry ABA level greatly increased, while LS and control treatments resulted in a gradual increase in berry ABA. In ES-treated vines, clusters were harvested 10 d after the onset of treatment, 10 d earlier than in LS and control vines, due to the severe berry shrinking and leaf fall. Levels of juice TSS, fructose, glucose, and malate were generally lower than those of LS and control vines. Both ES and LS treatments resulted in significantly higher amino acid levels. The level of proline, however, the amino acid with highest amounts in Chardonnay grape berries, was lowest in ES-treated vines. This study reveals that the effect of water deficit stress on berry ripening of Chardonnay is different depending on the stage of berry ripening, which might be caused by different ABA levels in berries.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Influence of Vitis xylem fluid and xylem fluid plus cecropin on growth of Xylella fastidiosa
Creators: name: Andersen, P. C.
name: Ishida, M. L.
name: Momol, E. A.
name: Brodbeck, B. V.
name: Leite, B.
name: Momol, M. T.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Colony growth of Xylella fastidiosa (UCLA PD and STL PD strains) was quantified after incubation for 48 h in xylem fluid of Vitis rotundifolia Michx. cv. Noble and Vitis vinifera L. cv. Chardonnay. Xylem fluid was collected from grapevines in the field (dormant and growing season) and from container-grown plants in a screen house (growing season). Colony forming units·ml-1 (cfu·ml-1) were counted 15 d after plating on periwinkle wilt (PW+) medium. Colony growth was promoted or inhibited compared to PW+ medium, and was dependent on X. fastidiosa strain, plant species and source of xylem fluid. The efficacy of cecropin A and B was tested against this bacterium. Colony growth of X. fastidiosa was greatly inhibited after a 1-h-exposure to cecropin A or B. The minimum inhibitory concentration (MIC) of cecropin A or B for 100 % inhibition of X. fastidiosa was < 1 μM. The activity of cecropin B in xylem fluid of V. rotundifolia cv. Noble was progressively reduced over time from 0.2 to 24 h. When 2 and 10 μM concentrations of cecropin A and cecropin B were mixed with xylem fluid for 24 h, a substantial amount of bacterial growth occurred after subsequent plating; shorter time intervals did not degrade the cecropins and did not prevent colony growth. Cecropin B (1 μM) added to xylem fluid of V. rotundifolia cv. Noble and V. vinifera cv. Chardonnay for 24, 48, 72 and 96 h did not prevent subsequent colony growth. Colony number tended to be higher for V. rotundifolia cv. Noble than V. vinifera cv. Chardonnay. Tricine-sodium dodecyl sulphate polyacrylamide gel electrophoresis (Tricine-SDS-PAGE) of cecropin B in xylem fluid showed that cecropin B degraded completely (V. vinifera cv. Chardonnay) or almost completely (V. rotundifolia cv. Noble) after 96 h.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
title: Deep Learning in Neuronal and Neuromorphic Systems
Creators: name: Kriener, Laura Magdalena
Publisher: name: Universität Bern
Year: 2024
Subjects: subject: 610 Medicine & health

description: The ever-increasing compute and energy requirements in the field of deep learning have caused a rising interest in the development of novel, more energy-efficient computing paradigms to support the advancement of artificial intelligence systems. Neuromorphic architectures are promising candidates, as they aim to mimic the functional mechanisms, and thereby inherit the efficiency, of their archetype: the brain. However, even though neuromorphics and deep learning are, at their roots, inspired by the brain, they are not directly compatible with each other. In this thesis, we aim at bridging this gap by realizing error backpropagation, the central algorithm behind deep learning, on neuromorphic platforms.
We start by introducing the Yin-Yang classification dataset, a tool for neuromorphic and algorithmic prototyping, as a prerequisite for the other work presented. This novel dataset is designed to not require excessive hardware or computing resources to be solved. At the same time, it is challenging enough to be useful for debugging and testing by revealing potential algorithmic or implementation flaws. We then explore two different approaches of implementing error backpropagation on neuromorphic systems. Our first solution provides an exact algorithm for error backpropagation on the first spike times of leaky integrate-andfire neurons, one of the most common neuron models implemented in neuromorphic chips. The neuromorphic feasibility is demonstrated by the deployment on the BrainScaleS-2 chip and yields competitive results both with respect to task performance as well as efficiency. The second approach is based on a biologically plausible variant of error backpropagation realized by a dendritc microcircuit model. We assess this model with respect to its practical feasibility, extend it to improve learning performance and address the obstacles for neuromorphic implementation: We introduce the Latent Equilibrium mechanism to solve the relaxation problem introduced by slow neuron dynamics. Our Phaseless Alignment Learning method allows us to learn feedback weights in the network and thus avoid the weight transport problem. And finally, we explore two methods to port the rate-based model onto an event-based neuromorphic system. 
The presented work showcases two ways of uniting the powerful and flexible learning mechanisms of deep learning with energy-efficient neuromorphic systems, thus illustrating the potential of a convergence of artificial intelligence and neuromorphic engineering research.
A portable whole canopy gas exchange system for several mature field-grown grapevines
Creators: name: Perez-Peña, J.
name: Tarara, J.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Six flow-through chambers (8 m3 volume) were built to measure gas exchange (CO2 and H2O) of whole vines under deficit irrigation regimes that imposed water stress at different stages of berry development. Chamber design and materials were selected to minimize environmental effects, and to accommodate the trellis of a mature, field-grown vine. A framed design allowed the chambers to withstand sustained winds up to 13 m s-1, overcoming one disadvantage of the balloon-type chambers. At mid-canopy height, 1.6 m, air temperature inside the chamber was no more than 2.5 °C higher than at the same height in the canopy of an unchambered vine. Over 24 h, solar radiation inside the chamber was 90 % of ambient. For vines irrigated according to standard industry practice, maximum values of net CO2 exchange approached 12 μmol m-2 s-1, whereas in water-stressed vines the maxima approached only 6.5 μmol m-2 s-1. Transpiration among water-stressed plants was reduced, with maximum rates at 1 mmol m-2 s-1 while vines under standard irrigation were at 2.5 mmol m-2 s-1. Apparent light saturation for canopy photosynthesis was approximately 1200 μmol m-2 s-1 PPFD (photosynthetic photon flux density) for vines under standard irrigation, and about 800 μmol m-2 s-1 PPFD for vines under water stress.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 1 (2004): Vitis
Responsible Metrics at Kent
Creators: name: Sarah Slowe | Head Of Scholarly Communication
Publisher: name: Zenodo
Year: 2020
Subjects: Metrics, Responsible research indicators, scholarly communication

description: This is the main slide deck for our Responsible metrics presentation - we remove or adapt slides according to audience. Also happy to explain any slides that don't make sense or are too specific (e.g. the bodies of water slide, one is the Great Lakes, one is the duck pond on our Canterbury campus).
Wood Warbler Phylloscopus sibilatrix nest provisioning rates are correlated with seasonal caterpillar availability in British Oak Quercus woodlands
Creators: name: Whytock, Robin C.
name: Davis, Daniel
name: Whytock, Rory T.
name: Burgess, Malcolm D.
name: Minderman, Jeroen
name: Mallord, John W.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Physiology

description: Capsule Maximum provisioning rates occurred during the seasonal peak in caterpillar availability, controlling for brood age and time of day.Aims To determine if the seasonal availability of caterpillars influenced Wood Warbler Phylloscopus sibilatrix nest provisioning rates.Methods Remote cameras were used to monitor nest visits at 14 nests in 8 British oak Quercus woodlands during 2013. The timing of the caterpillar peak was estimated by monitoring the production of caterpillar faecal pellets under oak trees.Results Maximum provisioning rates occurred when the date of provisioning coincided with the date of peak caterpillar availability, but the percentage change in provisioning rates during asynchrony was dependent on brood age. Younger broods experienced a greater decline in provisioning rates than older broods during asynchrony. Provisioning rates peaked in the morning and declined during the day, but when caterpillar availability was low there was little within-day variation.Conclusion Provisioning rates show seasonal variation that is correlated with caterpillar availability. Previous studies suggest that Wood Warbler reproductive fitness is independent of synchrony between the breeding cycle and the caterpillar peak, however, the implications for adult fitness are unknown and should be investigated further.
Classification of landforms in Southern Portugal (Ria Formosa Basin)
Creators: name: Martins, Fernando M. G.
name: Fernandez, Helena M.
name: Isidoro, Jorge M. G. P.
name: Jordán, Antonio
name: Zavala, Lorena
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: A Geographic Information Systems-based tool is used for macro-landform classification following the Hammond procedure, based upon a Digital Terrain Model (DTM) created from ordinary Kriging. Gentle slopes, surface curvature, highlands and lowlands areas are derived from the DTM. Combining this information allows the classification of terrain units (landforms). The procedure is applied to the Ria Formosa basin (Southern Portugal), with five different terrain types classified (plains, tablelands, plains with hills, open hills and hills).
Dynamic surface deformation of silicone elastomers for management of marine biofouling: laboratory and field studies using pneumatic actuation
Creators: name: Phanindhar Shivapooja
name: Qiming Wang
name: Szott, Lizzy M.
name: Orihuela, Beatriz
name: Rittschof, Daniel
name: Xuanhe Zhao
name: López, Gabriel P.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology

description: Many strategies have been developed to improve the fouling release (FR) performance of silicone coatings. However, biofilms inevitably build on these surfaces over time. Previous studies have shown that intentional deformation of silicone elastomers can be employed to detach biofouling species. In this study, inspired by the methods used in soft-robotic systems, controlled deformation of silicone elastomers via pneumatic actuation was employed to detach adherent biofilms. Using programmed surface deformation, it was possible to release > 90% of biofilm from surfaces in both laboratory and field environments. A higher substratum strain was required to remove biofilms accumulated in the field environment as compared with laboratory-grown biofilms. Further, the study indicated that substratum modulus influences the strain needed to de-bond biofilms. Surface deformation-based approaches have potential for use in the management of biofouling in a number of technological areas, including in niche applications where pneumatic actuation of surface deformation is feasible.
Classification of landforms in Southern Portugal (Ria Formosa Basin)
Creators: name: Martins, Fernando M. G.
name: Fernandez, Helena M.
name: Isidoro, Jorge M. G. P.
name: Jordán, Antonio
name: Zavala, Lorena
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: A Geographic Information Systems-based tool is used for macro-landform classification following the Hammond procedure, based upon a Digital Terrain Model (DTM) created from ordinary Kriging. Gentle slopes, surface curvature, highlands and lowlands areas are derived from the DTM. Combining this information allows the classification of terrain units (landforms). The procedure is applied to the Ria Formosa basin (Southern Portugal), with five different terrain types classified (plains, tablelands, plains with hills, open hills and hills).
A QM/MM study of the molecular recognition site of bapineuzumab toward the amyloid-β peptide isoforms
Creators: name: Gutierrez, Lucas J.
name: Exequiel E. Barrera Guisasola
name: Nelida Peruchena
name: Enriz, Ricardo D.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Information and Computing Sciences
Biological Sciences
Chemistry
Earth and Environmental Sciences
Molecular Biology
Biochemistry
Biophysics

description: The molecular mechanism of recognition of amyloid-beta (Aβ) peptide isoforms by bapineuzumab was studied using a quantum mechanics and molecular mechanics (QM/MM) method. In this work, geometric optimisations were performed using the ONIOM2 scheme (at B3LYP/6-31G(d) amber)EE level) on the paratope of bapineuzumab together with the different forms of Aβ peptide (AβWT and AβN3(pE)). A comprehensive study of the interactions was also performed through Quantum Theory of Atoms in Molecules (QTAIM). This allowed us to obtain a deep understanding of how this antibody interacts with the amino acids of the Aβ peptides. The description on the interactions between bapineuzumab and the different forms of Aβ peptides allow us to understand why the peptides that lack the two first residues (Asp1 and Ala2) and begin with a pyroglutamate residue present low affinity for bapineuzumab. This basic structural information is useful for a deeper understanding about the scope and limitations of bapineuzumab as a therapeutic agent for the AD.
РЕЗУЛЬТАТЫ ИСПОЛЬЗОВАНИЯ НОВЫХ КРИТЕРИЕВ ДИАГНОСТИКИ И ЛЕЧЕНИЯ ГЕСТАЦИОННОГО САХАРНОГО ДИАБЕТА
Creators: name: Равшанов, Шерхонбек
name: Туркманова, Марджона
name: Тауров, Мурад
name: Мирзаев, Ризамат
Publisher: name: Zenodo
Year: 2024

description: Учитывая высокую частоту перинатальных осложнений у женщин с гестационным сахарным диабетом (ГСД), необходим эффективный алгоритм диагностики и лечения данного заболевания. Нами проанализированы особенности течения и исходы беременности у 500 женщин с ГСД, у которых использованы новые клинические рекомендации диагностики и лечения гестационного сахарного диабета. Группу сравнения составили 100 женщин с ГСД (критерии В.Г. Баранова, 1977 г.). Анализ результатов необходим для оптимизации тактики ведения данной группы больных.
Apoptosis and cancer: insights molecular mechanisms and treatments
Creators: name: Iqbal, Zahid
name: Md. Ataur Rahman*
name: Md. Tipu Sultan
name: Md. Rokibul Islam
Publisher: name: figshare
Year: 2015
Subjects: subject: Education
subject: Genetic Engineering
subject: Biophysics
subject: Biological Techniques
subject: Biotechnology
subject: Genetics
subject: FOS: Biological sciences

description: Apoptosis is a form of cell death that permits the removal of damaged, senescent or unwanted cells in multicellular organisms, without damage to the cellular microenvironment, but it is also involved in a wide range of pathological processes, including cancer. An understanding of the underlying mechanism of apoptosis is important as it plays a pivotal role in the pathogenesis of many diseases. Defective apoptosis represents a major causative factor in the development and progression of cancer. The majority of chemotherapeutic agents, as well as radiation, utilize the apoptotic pathway to induce cancer cell death. Recent knowledge on apoptosis has provided the basis for novel targeted therapies that exploit apoptosis to treat cancer by acting in the extrinsic/intrinsic pathway. Defects can occur at any point along these pathways, leading to malignant transformation of the affected cells, tumour metastasis and resistance to anticancer drugs. In particular, this review provides references concerning the apoptotic molecules, their interactions, the mechanisms involved in apoptosis resistance, and also the modulation of apoptosis for the treatment of cancer. Despite being the cause of problem, apoptosis plays an important role in the treatment of cancer as it is a popular target of many treatment strategies.
A comparative study of 2-chlorophenol, 2,4-dichlorophenol, and 2,4,6-trichlorophenol adsorption onto polymeric, commercial, and carbonaceous adsorbents
Creators: name: Simsek, Esra Bilgin
name: Aytas, Burcu
name: Duranoglu, Dilek
name: Ulker Beker
name: Trochimczuk, Andrzej W.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: In this study, polymeric and carbonaceous type of adsorbents were synthesized and their 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP), and 2,4,6-trichlorophenol (2,4,6-TCP) adsorption performances were compared with commercial available XAD-4 resin. Peach stone-based activated carbon (AC) was fabricated by steam activation and porous copolymer of cyanomethyl styrene–divinylbenzene was synthesized by suspension polymerization method. A comparative examination of chlorophenols (CPs) adsorption onto AC, polymeric, and XAD-4 resin was conducted in batch and continuous systems. Zeta potential and potentiometric titration data were analyzed for three adsorbents. The equilibrium data were fitted to the common types of adsorption isotherm and kinetic models. Freundlich model illustrated best fit to the experimental data. The adsorption kinetic obeys the pseudo-second-order model indicating that the chemical sorption is the rate-controlling parameter for chlorophenolic pollutants. The kinetic results also revealed that the rate of uptake is dependent on the acidity and hydrophobicity of CPs and the adsorbents showed excellent removal efficiency toward 2,4,6-TCP. The positive ΔH° and ΔS° values indicated endothermic nature and the increasing randomness at the solid–liquid interface during sorption process. Breakthrough curves obtained from column study revealed that the order of longer column saturation time was obtained as: 2,4,6-TCP > 2,4-DCP > 2-CP.
A comparative study of 2-chlorophenol, 2,4-dichlorophenol, and 2,4,6-trichlorophenol adsorption onto polymeric, commercial, and carbonaceous adsorbents
Creators: name: Simsek, Esra Bilgin
name: Aytas, Burcu
name: Duranoglu, Dilek
name: Ulker Beker
name: Trochimczuk, Andrzej W.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: In this study, polymeric and carbonaceous type of adsorbents were synthesized and their 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP), and 2,4,6-trichlorophenol (2,4,6-TCP) adsorption performances were compared with commercial available XAD-4 resin. Peach stone-based activated carbon (AC) was fabricated by steam activation and porous copolymer of cyanomethyl styrene–divinylbenzene was synthesized by suspension polymerization method. A comparative examination of chlorophenols (CPs) adsorption onto AC, polymeric, and XAD-4 resin was conducted in batch and continuous systems. Zeta potential and potentiometric titration data were analyzed for three adsorbents. The equilibrium data were fitted to the common types of adsorption isotherm and kinetic models. Freundlich model illustrated best fit to the experimental data. The adsorption kinetic obeys the pseudo-second-order model indicating that the chemical sorption is the rate-controlling parameter for chlorophenolic pollutants. The kinetic results also revealed that the rate of uptake is dependent on the acidity and hydrophobicity of CPs and the adsorbents showed excellent removal efficiency toward 2,4,6-TCP. The positive ΔH° and ΔS° values indicated endothermic nature and the increasing randomness at the solid–liquid interface during sorption process. Breakthrough curves obtained from column study revealed that the order of longer column saturation time was obtained as: 2,4,6-TCP > 2,4-DCP > 2-CP.
Extraction of β-galactosidase and β-glucosidase from the seeds of Tamarindus indica
Creators: name: Iqbal, Zahid
name: Shlini Purushothaman*
name: Siddalinga Murthy K R
Publisher: name: figshare
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Education
subject: Botany
subject: Biophysics
subject: Biological Engineering
subject: Pharmacology

description: The enzymes β–galactosidase and β–glucosidase were extracted from the tamarind seeds using different buffers at different pH. Highest activity was obtained with 10 mM sodium acetate buffer, pH 5.6 and 10 mM tris buffer, pH 7.4. The effect of NaCl and Triton X–100 at different concentrations on the extraction of the enzymes indicated 10 mM sodium acetate buffer, pH 5.6 containing 1 M NaCl as a better extractant of the enzyme. The enzyme assay was carried out using p–nitrophenyl–β–D–galactoside and p–nitrophenyl–β–D–glucoside as substrates. Highest enzyme activities were observed on 6th and 24th day of germination. The protein content gradually decreased upto 5th day of germination and suddenly increased on 6th day. However, on subsequent days of germination, the protein content greatly decreased upto 11th day. During the latter period of germination (18th day onwards) the content remained almost constant. The kinetic parameters varied for both β–galactosidase and β–glucosidase. The activity of β–galactosidase was show to have an optimal operating condition at pH 5.5 and a temperature of 500C. The thermostability of the enzyme was in the range of 400C – 700C with the pH stability in the range of 5.0 – 7.0. The Km and Vmax values for pNPGal were determined as 66μM and 2.27nmolesmin-1. In contrast the activity of β–glucosidase was shown to have an optimal operating condition at pH 5.0 and a temperature of 300C. The thermostability of the enzyme was in the range of 270C – 350C with the pH stability in the range of 4.0 – 7.0. The Km and Vmax values for pNPGlu were determined as 121μM and 5.26nmolesmin-1. The presented study is a preliminary work carried out for the standardization of protocols. The purification and characterization of β–galactosidase and β–glucosidase is under progress.
Efficient one-pot synthesis of (anthracen-9-yl)methyl sulfane derivatives
Creators: name: Gopalakrishnan, Reshma
name: Jomon P. Jacob
name: Chirakandathil, Ranjith
name: Perupparampil A. Unnikrishnan
name: Sreedharan Prathapan
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Biochemistry

description: A series of unsymmetrical (anthracen-9-yl)methyl sulfanes have been synthesized using a one-pot reaction from (anthracen-9-yl)methyl alcohol, thiourea, and the corresponding alkyl halide and also by a base-promoted one-pot reductive coupling of tosylhydrazones with thiols.
Choosing the right treatment - combining clinicians’ expert knowledge with data-driven predictions
Creators: name: Maekawa, Eduardo
name: Jensen, Esben
name: van de Ven, Pepijn
name: Mathiasen, Kim
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 40
subject: Engineering

description: Context: This study proposes a Bayesian network model to aid mental health specialists making data-driven decisions on suitable treatments. The aim is to create a probabilistic machine learning model to assist psychologists in selecting the most suitable treatment for individuals for four potential mental disorders: Depression, Panic Disorder, Social Phobia, or Specific Phobia. Methods: This study utilized a dataset from 1,094 individuals in Denmark containing socio-demographic details and mental health information. A Bayesian network was initially employed in a purely data-driven approach and was later refined with expert knowledge, referred to as a hybrid model. The model outputted probabilities for each disorder, with the highest probability indicating the most suitable disorder for treatment. Results: By incorporating expert knowledge, the model demonstrated enhanced performance compared to a strictly data-driven approach. Specifically, it achieved an AUC score of 0.85 vs 0.80 on the test data. Furthermore, we evaluated some cases where the predictions of the model did not match the actual treatment. The symptom questionnaires indicated that these participants likely had comorbid disorders, with the actual treatment being proposed by the model with the second highest probability. Conclusions: In 90.1% of cases, the hybrid model ranked the actual disorder treated as either the highest (67.3%) or second-highest (22.8%) on the test data. This emphasizes that instead of suggesting a single disorder to be treated, the model can offer the probabilities for multiple disorders. This allows individuals seeking treatment or their therapists to incorporate this information as an additional data-driven factor when collectively deciding on which treatment to prioritize
title: Stachelbeere :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 2011

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
OpenSesame: An example of stimulus presentation in Virtual Reality headsets (Oculus Rift DK1)
Creators: name: Hernández-Sande, Alberto
name: Lorca, José Andrés
Publisher: name: figshare
Year: 2015
Subjects: subject: Applied Psychology
subject: Computer Software
subject: FOS: Computer and information sciences
subject: Behavioral Neuroscience

description: Download the full example here: http://dx.doi.org/10.6084/m9.figshare.1394985 A Virtual Reality headset can help to improve focus in the stimulus by participants with normal vision, plus additional possibilities with 3D and depth perception. We hope that the initial setup for working with OpenSesame (2.9.5) and VR technology would be faster and easier with this brief guide.
We will work with the first Oculus Rift Development Kit. It has a screen with 1280x800 px. Newer versions has a higher quality screen, so the resolution changes and you must change this value in consequence, but the logic and the basis stay the same.
La "CLEE" des "CLES" une alternative à la production agricole dans le sous-bassin de la haute Comoé au Burkina Faso
Creators: name: Tionyélé FAYAMA
name: Babou NEBIE
name: Victorien SAWADOGO
Publisher: name: Zenodo
Year: 2024

description: La gouvernance des ressources en eau est une préoccupation majeure pour les Etats du monde en l’occurrence ceux de l’Afrique subsaharienne. L’accès à l’eau potable, l’usage de l’eau agricole et la pollution des eaux sont autant de problèmes auxquels le monde est confronté. De ce fait, plusieurs institutions nationales et internationales accordent une place de choix à la gestion intégrée des ressources en eau (GIRE). Au Burkina Faso, il est mis en place dans le cadre de la politique nationale de gestion en eaux, les sous-bassins de la Haute Comoé des initiatives qui permettent aux communautés de gérer les ressources en eau de manière endogène. Ces initiatives se traduisent par la mise en place des comités locaux de l’eau qui sont considérés comme des maillons de base du cadre institutionnel de la GIRE. Dans cette zone, l’agriculture irriguée constitue une source importante de revenus pour la population. D’où la pression des exploitants agricoles sur les ressources en eau disponibles. Cette étude se veut être une contribution à la gestion des ressources en eau en vue d’améliorer la production agricole à travers la dynamisation des comités locaux de l’eau dans un contexte de changement climatique. Ainsi, l’article s’interroge sur les avantages des Comités Locaux de l’Eau du sous-bassin de la Haute Comoé dans la gestion des ressources en eau et aussi sur les difficultés auxquelles ils font face. La méthodologie repose sur une démarche mixte où nous avons conduit une enquête terrain auprès de 182 usagers agricoles du sous-bassin à travers un questionnaire individuel semi-directif pour la collecte des données et aussi mené des entretiens individuels.