cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Conditions of participation in sport clubs for people with disabilities
Creators: name: Klenk, Christoffer
name: Albrecht, Julia
name: Nagel, Siegfried
Publisher: name: UK FTVS
Year: 2017
Subjects: 790 Sports, games & entertainment
300 Social sciences, sociology & anthropology

description: Sport participation provides important bio-psycho-social benefits for people with disabilities. However, the disabled population’s engagement in physical activity is less than the non-disabled, especially in the organized sport setting. Moreover, people with disabilities often practice sport in separate settings, suggesting there are various barriers to sport participation (Jaarsma et al., 2014). This research considers conditions at the organizational level of disability and regular sport clubs that affect club culture (e.g. values), formal structure (e.g. resources) and practices (e.g. social interactions) (Booth & Ainscow, 2002). The research compares the conditions of separate training groups for people with disabilities with inclusive ones for people with and without disabilities. A case study of 15 training groups (9 separate, 6 inclusive) in Switzerland with observations of training sessions and interviews with coaches was conducted. In addition, club officials completed a questionnaire on club structure. Initial results reveal greater differences between different disability forms than between settings. For example, training groups for people with mental disabilities require less complex and fewer exercises. The results might help designing measures to increase sport participation of people with disabilities in sport clubs. References Booth, T. & Ainscow, M. (2002). Index for Inclusion. Bristol: Centre for Studies on Inclusive Education (CSIE). Jaarsma, E. A., Dijkstra, P. U., Geertzen J. H. B. & Dekker, R. (2014). Barriers to and facilitators of sports participation for people with physical disabilities: A systematic review. Scandinavian Journal of Medicine & Science in Sports, 24, 871–881.
Exploratory trials in mental health: anything to learn from other disciplines?
Creators: name: Trelle, Sven
Publisher: name: BMJ Publishing Group
Year: 2017

description: OBJECTIVE Confirmatory randomised controlled trials require solid justifications, especially with regard to whether the experimental intervention is promising. Such evidence is generated in exploratory trials. However, empirical evidence shows that the quality of such trials is still suboptimal. More generally, the development process of healthcare interventions and especially of drugs, remains inefficient. Over the past 10-20 years, a vast amount of methodological work has been published about exploratory trials. This overview introduces some of the concepts and recent developments in the field. METHODS A narrative approach was taken for this overview. This article focuses on study designs developed outside the mental health field to introduce concepts that might not be familiar to clinical researchers in psychiatry and psychology. Non-randomised and randomised exploratory trial designs are covered. The article ends with a brief discussion on pilot studies and their difference to exploratory studies. RESULTS Classical designs for exploratory trials such as Simon's two-stage design still have a role. However, randomised exploratory trials are probably more suitable for mental health interventions. Newer, more flexible designs such as multistage, multiarm trials or platform trials have the potential to improve the efficiency of exploratory and subsequently confirmatory experiments. CONCLUSIONS Although often not directly applicable, borrowing (study) design ideas from other medical disciplines has the potential to improve exploratory trials in the mental health field. At the same time, more explicit use of study designs specifically designed for exploratory trials will help to improve the transparency of such trials.
Additional file 1 of The impact of social determinants of health on early childhood development: a qualitative context analysis in Iran
Creators: name: Atashbahar, Omolbanin
name: Sari, Ali Akbari
name: Takian, Amirhossein
name: Olyaeemanesh, Alireza
name: Mohamadi, Efat
name: Barakati, Sayyed Hamed
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1.
Defining optimal health range for thyroid function based on the risk of cardiovascular disease.
Creators: name: Chaker, L
name: Korevaar, T I M
name: Rizopoulos, D
name: Collet, T-H
name: Völzke, H
name: Hofman, A
name: Rodondi, Nicolas
name: Cappola, A R
name: Peeters, R P
name: Franco, O H
Publisher: name: Endocrine Society
Year: 2017
Subjects: 610 Medicine & health
360 Social problems & social services

description: Context Reference ranges of thyroid stimulating hormone (TSH) and free thyroxine (FT4) are defined by their distribution in apparently healthy populations, (2.5th and 97.5th percentiles) irrespective of disease risk and used as cut-offs for defining and clinically managing thyroid dysfunction. Objective To provide a proof of concept in defining thyroid function optimal health ranges based on cardiovascular disease (CVD) mortality risk. Design and Participants 9,233 participants from the Rotterdam Study (mean age 65.0 years) were followed up (median 8.8 years) from baseline to date of death or end of follow-up (2012), which ever came first (689 cases of CVD mortality). Main Outcomes We calculated 10-year absolute risks of CVD mortality (defined according to SCORE project) using a Fine and Grey competing risk model per percentile of TSH and FT4, modelled non-linearly and sex- and age-adjusted. Results Overall, FT4 > 90th percentile was associated with a predicted 10-year CVD mortality risk >7.5% (p =0.005). In men, FT4 > 97th percentile was associated with a risk of 10.8% (p<0.001). In participants ≥ 65 years, absolute risk estimates were <10.0% below the 30th percentile (∼14.5 pmol/L or 1.10 ng/dL) and ≥15.0% above the 97th percentile of FT4 (∼22 pmol/L or 1.70 ng/dL). Conclusions We describe absolute 10-year CVD mortality risks according to thyroid function (TSH and FT4) and suggest optimal health ranges for thyroid function can be defined according to disease risk and are possibly sex and age-dependent. These results need to be replicated with sufficient samples and representative populations.
Wirkfaktoren psychosozialer Behandlungen bei Sucht und komorbiden psychischen Störungen
Creators: name: Moggi, Franz
Publisher: name: Schattauer
Year: 2016
Subjects: 610 Medicine & health

description: Gegenstand und Ziel: Es werden die wichtigsten Wirkfaktoren erfolgreicher psychosozialer Behandlungen von Patienten mit einer Komorbidität von psychischen Störungen und Sucht (Doppeldiagnosen) herausgearbeitet. Material und Methoden: In den drei wissenschaftlichen Datenbanken PubMed, PsycINFO und Web of Science wurden neuere Metaanalysen und umfassende Übersichtsarbeiten zur Wirksamkeit psychosozialer Behandlungen bei Doppeldiagnosepatienten gesucht und aus deren Ergebnisse das vorliegende „narrative review“ erarbeitet. Dabei wird näher auf die Studienergebnisse zu schweren und zu leichten Formen von Komorbidität eingegangen. Ergebnisse: Integrative, gestufte Behandlungsprogramme, die störungsspezifische Interventionen kombinieren, sind Kontrollgruppen (z.B. Wartegruppen, Standardbehandlungen) meistens, bzw. anderen aktiven Behandlungen (z.B. Psychoedukation) manchmal in den drei Ergebnisbereichen (Sucht, psychische Störung und Funktionsniveau) überlegen. Erfolgreiche Behandlungsprogramme enthalten meist motivierende Gesprächsführung, kognitiv-verhaltenstherapeutische Interventionen, suchtmittelreduzierende Interventionen wie Rückfallprävention oder Kontingenzmanagement und/oder Familieninterventionen. Schlussfolgerung: Die Heterogenität der Patienten-, Behandlungs-, Settings- und Ergebnismerkmale erschweren allgemeingültige Schlussfolgerungen über die Wirksamkeit psychosozialer Behandlungen. Bei Patienten mit Doppeldiagnosen sind integrierte Behandungsangebote am erfolgversprechendsten.
Prevalence of contact allergy in the general population in different European regions
Creators: name: Coenraads, P.-J.
name: Svensson, Å.
name: Cazzaniga, Simone
name: Bertuccio, P.
name: Diepgen, T.L.
name: Goncalo, M.
name: Elsner, P.
name: Naldi, L.
name: Ofenloch, R.F.
name: Bruze, M.
Publisher: name: Wiley-Blackwell
Year: 2016
Subjects: 610 Medicine & health

description: Background Population-based studies about contact allergy are scarce. Objectives To obtain reliable estimates of the prevalence of contact allergy in the general population in Europe. Methods A cross-sectional study of a random sample from the general population, aged 18–74 years, in five different European countries (Sweden, the Netherlands, Germany, Italy and Portugal). In total, 12 377 subjects were interviewed and a random sample (n = 3119) patch tested to TRUE Test panels 1–3 and Fragrance Mix (FM) II, hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) and sesquiterpene lactone mix. A positive patch test reaction is considered as contact allergy. Results In total, 27·0% [95% confidence interval (CI) 25·5–28·5] had at least one positive reaction to an allergen of the European baseline series, with a significantly higher prevalence in women than in men. The highest age-standardized prevalences (≥ 1%) were found for nickel (14·5%, 95% CI 13·2–15·8), thiomersal (5·0%, 95% CI 4·2–5·8), cobalt (2·2%, 95% CI 1·7–2·7), FM II (1·9%, 95% CI 1·5–2·5), FM I (1·8%, 95% CI 1·4–2·3), HICC (1·4%, 95% CI 1·0–1·9), p-tert-butylphenol formaldehyde resin (1·3%, 95% CI 0·9–1·7) and para-phenylenediamine (1·0%, 95% CI 0·6–1·3). Only nickel and thiomersal showed a statistically significantly different prevalence for contact allergy among the different European populations. Subjects reporting contact dermatitis in their lifetime (age-standardized prevalence 15·1%, 95% CI 13·8–16·3) had an increased risk for contact allergy (odds ratio 1·9, 95% CI 1·5–2·5). The risk of having a contact allergy was not increased in those with atopic dermatitis (prevalence 7·6%, 95% CI 6·7–8·6; odds ratio 1·0, 95% CI 0·7–1·4). Conclusions Contact allergy to at least one allergen of the European baseline series was diagnosed in more than one-quarter of the general European population. Therefore measures to improve the primary prevention of contact allergy have to be enforced.
Analysis of the social integration of adolescents and young adults with migration background in sports clubs
Creators: name: Nagel, Siegfried
name: Schlesinger, Torsten
Publisher: name: (:null)
Year: 2017
Subjects: 790 Sports, games & entertainment

description: Due to the complexity of the concept social integration, no sufficiently differentiated analytical tool exists to measure it, especially among people in sports clubs with a 78 migration background. As a result, studies have produced an ambivalent picture of how well-integrated immigrant club members actually are. The aim of the present study is to develop a suitable analytical tool for measuring social integration in sports clubs. For this study, immigrant members of Swiss sports clubs (n = 298) were interviewed using an analytical tool that bases on a concept using the four dimensions Placement, Identification, Interaction und Culturation (Esser, 2009). A confirmatory factor analysis produced satisfactory results (χ2/df = 2.19, RMSEA = .06, SRMR = .07, CFI = .92). Compared with the item means, the immigrant members studied displayed above-average scores for social integration. On the one hand, it seems advisable to continue developing the analytical tool in order to increase the accuracy of its measurements. On the other hand, the existing analytical tool can conceivably be used to conduct bi- and multivariate analyses on the influence of individual features on the social integration in sports clubs. Keywords: Voluntary sport organisations; social integration; confirmatory factor analysis; Switzerland
Cervical cancer risk and impact of Pap-based screening in HIV-positive women on antiretroviral therapy in Johannesburg, South Africa.
Creators: name: Rohner, Eliane
name: Sengayi, Mazvita
name: Goeieman, Bridgette
name: Michelow, Pamela
name: Firnhaber, Cynthia
name: Maskew, Mhairi
name: Bohlius, Julia
Publisher: name: Wiley-Blackwell
Year: 2017
Subjects: 610 Medicine & health
360 Social problems & social services

description: Data on invasive cervical cancer (ICC) incidence in HIV-positive women and the effect of cervical cancer screening in sub-Saharan Africa are scarce. We estimated i) ICC incidence rates in women (≥18 years) who initiated antiretroviral therapy (ART) at the Themba Lethu Clinic (TLC) in Johannesburg, South Africa, between 2004 and 2011 and ii) the effect of a Pap-based screening program. We included 10,640 women; median age at ART initiation: 35 years [interquartile range (IQR) 30-42], median CD4 count at ART initiation: 113 cells/µL (IQR 46-184). During 27,257 person-years (pys), 138 women were diagnosed with ICC; overall incidence rate: 506/100,000 pys [95% confidence interval (CI) 428-598]. The ICC incidence rate was highest (615/100,000 pys) in women who initiated ART before cervical cancer screening became available in 04/2005 and was lowest (260/100,000 pys) in women who initiated ART from 01/2009 onward when the cervical cancer screening program and access to treatment of cervical lesions was expanded [adjusted hazard ratio (aHR) 0.42, 95% CI 0.20-0.87]. Advanced HIV/AIDS stage (4 versus 1, aHR 1.95, 95% CI 1.17-3.24) and middle age at ART initiation (36-45 versus 18-25 years, aHR 2.51, 95% CI 1.07-5.88) were risk factors for ICC. The ICC incidence rate substantially decreased with the implementation of a Pap-based screening program and improved access to treatment of cervical lesions. However, the risk of developing ICC after ART initiation remained high. To inform and improve ICC prevention and care for HIV-positive women in sub-Saharan Africa, implementation and monitoring of cervical cancer screening programs are essential.
Additional file 1 of The effectiveness of adjunctive measures in managing peri-implant mucositis: an umbrella review
Creators: name: Chuachamsai, Sompol
name: Acharya, Aneesha
name: Fischer, Kai
name: Nibali, Luigi
name: Ho, Dominic
name: Pelekos, Georgios
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Eligibility criteria form. Table S2. Excluded reviews at the assessment of full-text and the main reasons for exclusion. Table S3. Characteristic of primary studies and overlap amongst systematic reviews of adjunctive antiseptic treatment. Table S4. Characteristic of primary studies and overlap amongst systematic reviews of adjunctive probiotic treatment. Table S5. Characteristic of primary studies and overlap amongst systematic reviews of adjunctive air-polishing treatment. Table S6. Characteristic of primary studies and overlap amongst systematic reviews of adjunctive laser and photodynamic treatment. Table S7. Characteristic of primary studies and overlap amongst systematic reviews of adjunctive local and systemic antibiotic treatment. Additional document 1. Data items of the systematic reviews and primary studies.
Familia honor y poder. La nobleza de la ciudad de Quito durante la época colonial tardía (1765- 1822)
Creators: name: Büschges, Christian
Publisher: name: FONSAL
Year: 2007
Subjects: 980 History of South America

description: Con este trabajo sobre la nobleza de la ciudad de Quito, Christian Büschges amplía el campo de los estudios socio-económicos y políticos sobre las así llamadas élites coloniales, con un análisis que se enfoca de manera especial en las mentalidades y representaciones estamentales, que tan fuertemente marcaron las relaciones sociales del antiguo régimen colonial.
title: "Aber der wirkliche Kampf stimmt schlecht mit den Anforderungen der Belletristik"??
Creators: name: Walch, Anna
Year: 2010

description: Literarische Texte spiegeln gesellschaftliche Sinnzuschreibungen ebenso, wie sie an diesen mitwirken, sie absorbieren soziale Deutungsmuster und schaffen ihre eigenen. Die vorliegende Arbeit postuliert ein literarisches Phänomen: Eine neue „Literatur der Arbeit“, welche Anfang des 2. Jahrtausends als Reaktion auf die Transformationen der Arbeitswelt entstand und deren Bedingungen in den neuen technischen Möglichkeiten des Internets liegen. Untersucht wird, wie drei zentrale Texte ihr Phänomen konstru-ieren, welche Art von Problem sie erschaffen, welche ursächlichen Zusammenhänge und Handlungsmöglichkeiten sie anbieten. Historische Spielarten der Darstellung von menschlicher Arbeit in der Literatur werden ebenso wie zeitgenössische Konzeptionen von Arbeit als Kontext der Texte erschlossen.
Observing The Effect Of Galaxy Environment On The Evolution Of Active Galactic Nuclei In The Era Of Multiplexed Wide-Field Fibre-Optic Spectroscopy
Creators: name: Gordon, Yjan Arthur
Publisher: name: Zenodo
Year: 2018
Subjects: Galaxy evolution
Active Galactic Nuclei
Galaxy environment

description: In this thesis, we use the environment of active galactic nuclei (AGN) to test AGN unification. Furthermore, we analyse how interaction between the environment and host galaxy can influence AGN evolution. This is done for a range of galaxy densities, from the field to the cores of galaxy clusters.

We utilise the high spectroscopic completeness of the Galaxy And Mass Assembly survey (GAMA) to perform a comparative analysis of the pair-wise environments of broad- and narrow-line AGN. Our observations show no difference in the frequency of broad- and narrow-line AGN in all but the tightest galaxy pairs. Furthermore, our observations show no difference in the colour or star-forming properties of the neighbouring galaxies of AGN, contrary to previous works. These observations are consistent with AGN unification and indicate that close galaxy interactions may increase nuclear obscuration.

Optically selected AGN preferentially inhabit infall regions of massive clusters, and are rarely found in the cluster core. Using the depth and completeness of GAMA, we optically select 451 AGN from 695 groups in the halo mass range 11.5 < log_{10}(M_{200}/M_{\odot}) < 14.5 at z < 0.15. At log_{10}(M_{200}/M_{\odot}) > 13:5 our results are similar to previous works on clusters with a deficit of AGN observed in the group core at 3:6 confidence. At lower halo masses no preferred location for AGN is seen.

Weakly accreting radio AGN are found in dense galactic environments, and minor-mergers have been invoked as a plausible mechanism to ‘drip-feed’ these low-excitation radio galaxies (LERGs). We use deep optical imaging from the Dark Energy Camera Legacy Survey (DECaLS) to search for low-surface brightness tidal remnants in a sample of 189 LERGs. We observe such tidal features in 27+3.5/-3.0 per cent of LERGs compared to 31.5+2.5/-2.3 per cent of a control sample. Our results are thus inconsistent with the hypothesis that minor-mergers play a significant role in LERG fuelling.
The Hidradenitis suppurativa patient journey in Italy: current status, unmet needs and opportunities.
Creators: name: Fantini, F
name: Piccolo, D
name: Pintori, G
name: Caracciolo, S
name: Pasquinucci, S
name: Bettoli, V
name: Cazzaniga, Simone
name: Naldi, L
name: Binello, L
Publisher: name: Wiley
Year: 2016
Subjects: 610 Medicine & health

description: BACKGROUND Hidradenitis suppurativa (HS) is a chronic, progressive inflammatory, debilitating, follicular disease of the skin with a reported incidence of less than 1% in the general population. Diagnosis of HS may typically be delayed for years, and even when diagnosed, is challenging to treat. Thus, HS has considerable negative impact on patient quality of life. OBJECTIVES To describe the HS patient journey in Italy, identify unmet needs and provide a proposal for integrated patient care. METHODS A multidisciplinary panel of leading Italian experts met to evaluate routine clinical practice and patient experience, and analyse the available scientific evidence on HS. RESULTS A comprehensive map of the journey of the HS patient in Italy was built based on integrated data obtained from clinical practice and patient experience. The journey is non-linear and can be grouped into four broad stages that are somewhat overlapping and intersecting: (i) onset to diagnosis; (ii) circle of visits; (iii) circle of treatments; (iv) living with HS. Several unmet needs were identified that included greater awareness of disease by both healthcare practitioners and patients. CONCLUSION Improved disease awareness can be addressed through continuing medical education for physicians and development of educational materials for patients, in addition to greater utilization of social networks. Moreover, the development of integrated treatment centres was considered a worthwhile goal, and would offer patients the possibility to receive multidisciplinary care, ideally with dermatologists coordinating treatment, along with surgeons, psychologists, endocrinologists, gastroenterologists, pain specialists, gynaecologists and paediatricians as needed. Lastly, standardized management protocols for HS are also needed.
Additional file 1 of Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models
Creators: name: Bezdieniezhnykh, N.
name: Lykhova, A.
name: Kozak, T.
name: Zadvornyi, T.
name: Borikun, T.
name: Voronina, O.
name: Lukianova, N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology

description: Additional file 1.
Additional file 1 of Hoslundia opposita vahl; a potential source of bioactive compounds with antioxidant and antibiofilm activity for wound healing
Creators: name: Namuga, Catherine
name: Muwonge, Haruna
name: Nasifu, Kerebba
name: Sekandi, Peter
name: Sekulima, Tahalu
name: Kirabira, John Baptist
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Wasser in der mittelalterlichen Kultur. Gebrauch – Wahrnehmung – Symbolik
Water in Medieval Culture. Uses, Perceptions, and Symbolism
Creators: name: (:Null)
Publisher: name: De Gruyter
Year: 2017
Subjects: 470 Latin & Italic languages
430 German & related languages
900 History
400 Language
440 French & related languages
800 Literature, rhetoric & criticism
830 German & related literatures
180 Ancient, medieval & eastern philosophy

description: Wasser ist Leben. Der individuelle Organismus, menschliche Sozialbildungen und Kulturleistungen sind auf das Wasser angewiesen. Es kann lebenserhaltend und zerstörend, verbindend und trennend, erlösend und auflösend wirken. Menschliche Gesellschaften und Institutionen sind gezwungen, sich diesen ambivalenten Funktionen zu stellen. Das natürliche Element Wasser fordert zu kulturellen Reaktionen im Bereich seiner Bewirtschaftung, Bewertung und Symbolik heraus. Alle Funktionen, die das Wasser in der realen Welt erfüllt, können auch in Literatur und Kunst thematisiert werden. Der Sammelband vereinigt, aufbauend auf dem 16. Symposium des Mediävistenverbands e.V. vom 22. bis 25. März 2015 in Bern, 47 Beiträge aus der Geschichtswissenschaft, Kunstgeschichte, Medizingeschichte, Theologie, Philosophie und aus den Literaturwissenschaften zu den Themenfeldern Wahrnehmungen von Flüssen, Meeren und Mündungen, Schifffahrt, Wassernutzung, Wasser in Religion, Ritus und Volksglaube, philologisch-literarische Annäherungen an das Wasser, Wassertiere in der Literatur sowie Wasser in der Architektur und Kunst. Es ist der erste Versuch überhaupt, die Rolle des Wassers in der mittelalterlichen Kultur derart umfassend und interdisziplinär zu beleuchten.
description: Water is life. Individual organisms, social formations, and cultural achievements all depend on water. It is used in both pragmatic and symbolic contexts. Being a life-sustaining as well as a destructive force, water connects and divides, absolves and dissolves. Society as a whole and individual institutions alike need to engage with, and adapt to, these ambivalent aspects of water. As a natural element, water provokes cultural reactions in regard to its utilisation, evaluation, and symbolism. The different functions water fulfils in the natural world are also addressed and negotiated in literature and the visual arts. This article provides a short introduction into the main research questions of the interdisciplinary conference of the “Mediävistenverband e.V.” held in Bern, Switzerland in March 2015, it gives a concise overview on previous publications in this field and it summarizes the findings of the overall volume.
Additional considerations are required when preparing a protocol for a systematic review with multiple interventions.
Creators: name: Chaimani, Anna
name: Caldwell, Deborah M
name: Li, Tianjing
name: Higgins, Julian Pt
name: Salanti, Georgia
Publisher: name: Elsevier
Year: 2017
Subjects: 610 Medicine & health
360 Social problems & social services

description: OBJECTIVES The number of systematic reviews that aim to compare multiple interventions using network meta-analysis is increasing. In this paper, we highlight aspects of a standard systematic review protocol that may need modification when multiple interventions are to be compared. STUDY DESIGN AND SETTING We take the protocol format suggested by Cochrane for a standard systematic review as our reference, and compare the considerations for a pairwise review with those required for a valid comparison of multiple interventions. We suggest new sections for protocols of systematic reviews including network meta-analyses with a focus on how to evaluate their assumptions. We provide example text from published protocols to exemplify the considerations. RESULTS AND CONCLUSION Standard systematic review protocols for pairwise meta-analyses need extensions to accommodate the increased complexity of network meta-analysis. Our suggested modifications are widely applicable to both Cochrane and non-Cochrane systematic reviews involving network meta-analyses.
Europol and Differentiated Integration
Creators: name: Mortera-Martínez, Camino
name: Nechev, Zoran
name: Damjanovski, Ivan
Publisher: name: Zenodo
Year: 2021
Subjects: European Union
Europol
Area of Freedom, Security and Justice (AFSJ)
Police cooperation

description: Europol has become a hub for differentiated integration. Initially a small anti-drugs unit, the EU’s police agency is now a fully-fledged body where law enforcement agencies from all around the world work together. Seen through the organisational dimension of differentiation, police cooperation through Europol has shaped differentiated integration modalities based both on the uneven participation of actors in the policy cycle and on the differentiated access to Europol’s mechanisms for exchange of information. Albeit limited, this multi-layered arrangement of police cooperation through Europol has provided the grounds for a more flexible approach towards the fight against organised crime in Europe. The various differentiated integration mechanisms at play have ultimately significantly increased transactions between law enforcement authorities in Europe and have improved cross-border cooperation in the areas within Europol’s mandate.
S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages.
Creators: name: Realegeno, Susan
name: Kelly-Scumpia, Kindra M
name: Dang, Angeline Tilly
name: Lu, Jing
name: Teles, Rosane
name: Liu, Philip T
name: Schenk, Mirjam
name: Lee, Ernest Y
name: Schmidt, Nathan W
name: Wong, Gerard C L
name: Sarno, Euzenir N
name: Rea, Thomas H
name: Ochoa, Maria T
name: Pellegrini, Matteo
name: Modlin, Robert L
Publisher: name: Public Library of Science
Year: 2016

description: Triggering antimicrobial mechanisms in macrophages infected with intracellular pathogens, such as mycobacteria, is critical to host defense against the infection. To uncover the unique and shared antimicrobial networks induced by the innate and adaptive immune systems, gene expression profiles generated by RNA sequencing (RNAseq) from human monocyte-derived macrophages (MDMs) activated with TLR2/1 ligand (TLR2/1L) or IFN-γ were analyzed. Weighed gene correlation network analysis identified modules of genes strongly correlated with TLR2/1L or IFN-γ that were linked by the "defense response" gene ontology term. The common TLR2/1L and IFN-γ inducible human macrophage host defense network contained 16 antimicrobial response genes, including S100A12, which was one of the most highly induced genes by TLR2/1L. There is limited information on the role of S100A12 in infectious disease, leading us to test the hypothesis that S100A12 contributes to host defense against mycobacterial infection in humans. We show that S100A12 is sufficient to directly kill Mycobacterium tuberculosis and Mycobacterium leprae. We also demonstrate that S100A12 is required for TLR2/1L and IFN-γ induced antimicrobial activity against M. leprae in infected macrophages. At the site of disease in leprosy, we found that S100A12 was more strongly expressed in skin lesions from tuberculoid leprosy (T-lep), the self-limiting form of the disease, compared to lepromatous leprosy (L-lep), the progressive form of the disease. These data suggest that S100A12 is part of an innate and adaptive inducible antimicrobial network that contributes to host defense against mycobacteria in infected macrophages.
title: Politische Medienkompetenz
Creators: name: Wassmuth, Sandra
Year: 2010

description: Erfahrungen in Politik sind häufig medienvermittelt. Große Bedeutung haben hier die Massenmedien. Wie gehen Kinder mit politischen Inhalten um? Welches Rüstzeug benötigen sie, um in der Gesellschaft kommunikativ handlungsfähig zu werden und kompetent mit Medien(inhalten) umzugehen. Politisch partizipationsbereit und medienkritischer Umgang sind geforderte Fähigkeiten unserer Zeit. Wie müssen politische Medieninhalte aufbereitet sein, dass sie für Kinder interessant sind und verarbeitet werden können? Politische Medienkompetenz als Schlüsselqualifikation in unserer Gesellschaft soll von mehreren Seiten gefördert werden. Welchen Beitrag leistet die Demokratie- und Medienwerkstatt in Wien dazu?
Additional file 2 of Hoslundia opposita vahl; a potential source of bioactive compounds with antioxidant and antibiofilm activity for wound healing
Creators: name: Namuga, Catherine
name: Muwonge, Haruna
name: Nasifu, Kerebba
name: Sekandi, Peter
name: Sekulima, Tahalu
name: Kirabira, John Baptist
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
"...sampt jrer waren Conterfactur". Illustrative Vielfalt in Conrad Gessners Druckwerk
Creators: name: (:Null)
Publisher: name: (:null)
Year: 2016
Subjects: 090 Manuscripts & rare books

description: Ausstellung des Zentrums Historische Bestände der Universitätsbibliothek Bern zu Conrad Gessners 500. Geburtstag vom 30. Mai bis 22. September 2016
Open Access - Aktuelle Entwicklungen
Creators: name: Schwennsen, Florian
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017

description: DESY Bibliothekskommission, Hamburg, DESY, Germany, 25 Sep 2017 - 25 Sep 2017
description: In diesem Vortrag präsentiere ich den aktuellen Status der Open Access Publikationen und gehe auf die Herausforderung ein, diesen Anteil weiter zu erhöhen. Zudem stelle ich den derzeitigen Stand von SCOAP3 und DEAL vor.
Mächtig prächtig. Karten aus dem Danckerts-Atlas
Creators: name: Schläfli, Michael
Publisher: name: (:null)
Year: 2017
Subjects: 550 Earth sciences & geology

description: Ausstellung des Zentrums Historische Bestände der Universitätsbibliothek Bern anlässlich der Restaurierung und Digitalisierung des 50-blättrigen Danckerts Atlasses aus der Zeit um 1700
D8.3 Data Management Plan (Intermediate Version)
Creators: name: Bravo, Candela
name: Almeida, Alexandre
name: Kachris, Christoforos
Publisher: name: Zenodo
Year: 2017
Subjects: Data management

description: The document provides the 1st update of the Data Management Plan (DMP) submitted in July 2016 (deliverable D8.2) of the VINEYARD project. The revision of DMP covers an update on the data management lifecycle for all datasets collected, processed or generated by the project, during the first eighteen months of the project.

The purpose of the Data Management Plan (DMP) is to provide an analysis of the main elements of the data management policy that will be used by the applicants with regard to all the datasets that will be generated by the project.

According to Digital Curation Centre (DCC), a DMP contributes to saving time and effort, makes research process easier, helps to validate if the necessary support is considered, and enables to make sound decisions.

The DMP supports project partners to:

• understand the data and use it when needed;

• ensure continuity if project staff leave or new researchers join;

• avoid unnecessary duplication e.g. re-collecting or re-working data;

• contribute to more collaboration and advances research;

• increase visibility and impact;

• manage citations of other researchers on your data.
O'ZBEK ADABIY TILIDA ISTAK MA'NOSINI BILDIRUVCHI VOSITALAR MA'NODOSHLIGI
Creators: name: Safarov, Firuz
Publisher: name: Zenodo
Year: 2024

description: Maqolada o‘zbek adabiy tilidagi istak ma’nosini bildiruvchi vositalar ma’nodoshligi tahlil qilingan. Istak semasi ham shart-istak mayli tarkibiga kiruvchi modal ma’no bo‘lib mazkur sema shart semasidan farqli ravishda subyektiv xususiyatga ega. O‘zbek adabiy tilida istak semasi shart-istak maylining -sa, -sa edi,  -sa ekan shakllari bilan ifodalanib koshki, zora, shoyad, qani endi, qani edi, koshkiydi, qaniydi yordamchi so‘zlari vositasida kuchaytiriladi. Binobarin -sa, -sa edi, -sa ekan shakllari bilan mazkur yordamchi so‘zlar orasida ma’nodoshlik mavjud bo‘lib yordamchi so‘zlar konnotatsiya ifodalashga xizmat qiladi.
Towards a Taxonomy of Unit Tests
Creators: name: Lanza, Michele
name: Nierstrasz, Oscar
name: Gaelli, Markus
Publisher: name: (:null)
Year: 2005
Subjects: 510 Mathematics
000 Computer science, knowledge & systems

description: Not all unit tests are alike. Some tests are simple one-liners, while others contain a battery of assertions. Certain tests focus on a single method, while others test interactions between methods. There are even tests that do not contain assertions at all. This can make it difficult for a developer to understand which methods are tested by which tests, to what degree they are tested, and what to take into account while refactoring. We have manually analyzed the test base of a large existing object-oriented system in order to derive a first taxonomy of unit tests. We have then developed some simple tools to semi-automatically categorize tests according to this taxonomy, and applied it to two case studies. Beside explaining our taxonomy, we report on our initial results using it, namely that a majority of unit tests focus on single methods and that our lightweight automatic categorization could already classify more than 50% of these single method commands.
Additional file 4 of Integrated mendelian randomization analyses highlight AFF3 as a novel eQTL-mediated susceptibility gene in renal cancer and its potential mechanisms
Creators: name: Wang, Qiming
name: Chen, Shaopeng
name: Wang, Gang
name: Zhang, Tielong
name: Gao, Yulong
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 4
On Vector-Valued Siegel Modular Forms of Degree $2$ and Weight $(j,2)$
Creators: name: Cl\'Ery
name: Geer, Van Der
Publisher: name: Deutsche Mathematiker-Vereinigung
Year: 2018

description: We formulate a conjecture that describes the vector-valued Siegel modular forms of degree~$2$ and level $2$ of weight ${\rm Sym}^j\otimes {\det}^2$ and provide some evidence for it. We construct such modular forms of weight $(j,2)$ via covariants of binary sextics and calculate their Fourier expansions illustrating the effectivity of the approach via covariants. Two appendices contain related results of Chenevier; in particular a proof of the fact that every modular form of degree $2$ and level $2$ and weight $(j,1)$ vanishes.
description: Documenta Mathematica, 2018, vol. 23, p. 1129-1156, 1431-0643
Additional file 1 of Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy
Creators: name: Li, Yu-An
name: Zhao, Chuan
name: Ge, Jing-Jing
name: Li, Cheng
name: Xue, Feng-Jun
name: Qi, Shao-Pei
name: Zhao, Chi
name: Kong, Chen-Chen
name: Zhang, Jun-Ping
Publisher: name: figshare
Year: 2024
Subjects: Pharmacology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 1.
Additional file 5 of Integrated mendelian randomization analyses highlight AFF3 as a novel eQTL-mediated susceptibility gene in renal cancer and its potential mechanisms
Creators: name: Wang, Qiming
name: Chen, Shaopeng
name: Wang, Gang
name: Zhang, Tielong
name: Gao, Yulong
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 5
Additional file 1 of Risk factors for postoperative pneumonia in patients undergoing hip fracture surgery: a systematic review and meta-analysis
Creators: name: Han, Seung-Beom
name: Kim, Sang-Bum
name: Shin, Kyun-Ho
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Additional file 1. Results of sensitive analysis for variables.
Thyroid Function Within the Normal Range, Subclinical Hypothyroidism and the Risk of Atrial Fibrillation.
Creators: name: Baumgartner, Christine
name: Da Costa, Bruno R
name: Collet, Tinh-Hai
name: Feller, Martin
name: Floriani, Carmen
name: Bauer, Douglas C
name: Cappola, Anne R
name: Heckbert, Susan R
name: Ceresini, Graziano
name: Gussekloo, Jacobijn
name: Den Elzen, Wendy P J
name: Peeters, Robin P
name: Luben, Robert
name: Völzke, Henry
name: Dörr, Marcus
name: Walsh, John P
name: Bremner, Alexandra
name: Iacoviello, Massimo
name: Macfarlane, Peter
name: Heeringa, Jan
name: Stott, David J
name: Westendorp, Rudi G J
name: Khaw, Kay-Tee
name: Magnani, Jared W
name: Aujesky, Drahomir
name: Rodondi, Nicolas
Publisher: name: Lippincott Williams & Wilkins
Year: 2017
Subjects: 610 Medicine & health
360 Social problems & social services

description: Background -Atrial fibrillation (AF) is a highly prevalent disorder leading to heart failure, stroke, and death. Enhanced understanding of modifiable risk factors may yield opportunities for prevention. The risk of AF is increased in subclinical hyperthyroidism, but it is uncertain whether variations in thyroid function within the normal range or subclinical hypothyroidism are also associated with AF. Methods -We conducted a systematic review and obtained individual participant data from prospective cohort studies that measured thyroid function at baseline and assessed incident AF. Studies were identified from MEDLINE and EMBASE databases from inception to July 27, 2016. The euthyroid state was defined as thyroid-stimulating hormone (TSH) 0.45 to 4.49 mIU/L, and subclinical hypothyroidism as TSH 4.5 to 19.9 mIU/L with free thyroxine (fT4) levels within reference range. The association of TSH levels in the euthyroid and subclinical hypothyroid range with incident AF was examined by using Cox proportional hazards models. In euthyroid participants, we additionally examined the association between fT4 levels and incident AF. Results -Of 30 085 participants from 11 cohorts (278 955 person-years of follow-up), 1958 (6.5%) had subclinical hypothyroidism and 2574 individuals (8.6%) developed AF during follow-up. TSH at baseline was not significantly associated with incident AF in euthyroid participants or those with subclinical hypothyroidism. Higher fT4 levels at baseline in euthyroid individuals were associated with increased AF risk in ageand sex-adjusted analyses (hazard ratio, 1.45; 95% confidence interval, 1.26-1.66, for the highest quartile versus the lowest quartile of fT4; P for trend ≤0.001 across quartiles). Estimates did not substantially differ after further adjustment for preexisting cardiovascular disease. Conclusions -In euthyroid individuals, higher circulating fT4 levels, but not TSH levels, are associated with increased risk of incident AF.
De novo FGF12 mutation in 2 patients with neonatal-onset epilepsy.
Creators: name: Van Allen, Margot I
name: Thompson, Michelle L
name: Bürki, Sarah Elisabeth
name: Evans, Daniel M
name: Bebin, E Martina
name: Demos, Michelle
name: Nelson, Tanya N
name: McKenzie, Marna B
name: Adam, Shelin
name: Toyota, Eric B
name: Connolly, Mary B
name: Farrer, Matthew J
name: Cooper, Gregory M
name: Guella, Ilaria
name: Huh, Linda
Publisher: name: American Academy of Neurology
Year: 2016

description: OBJECTIVE We describe 2 additional patients with early-onset epilepsy with a de novo FGF12 mutation. METHODS Whole-exome sequencing was performed in 2 unrelated patients with early-onset epilepsy and their unaffected parents. Genetic variants were assessed by comparative trio analysis. Clinical evolution, EEG, and neuroimaging are described. The phenotype and response to treatment was reviewed and compared to affected siblings in the original report. RESULTS We identified the same FGF12 de novo mutation reported previously (c.G155A, p.R52H) in 2 additional patients with early-onset epilepsy. Similar to the original brothers described, both presented with tonic seizures in the first month of life. In the first patient, seizures responded to sodium channel blockers and her development was normal at 11 months. Patient 2 is a 15-year-old girl with treatment-resistant focal epilepsy, moderate intellectual disability, and autism. Carbamazepine (sodium channel blocker) was tried later in her course but not continued due to an allergic reaction. CONCLUSIONS The identification of a recurrent de novo mutation in 2 additional unrelated probands with early-onset epilepsy supports the role of FGF12 p.R52H in disease pathogenesis. Affected carriers presented with similar early clinical phenotypes; however, this report expands the phenotype associated with this mutation which contrasts with the progressive course and early mortality of the siblings in the original report.
Additional file 1 of Pregnancy induced hypertension and umbilical cord blood DNA methylation in newborns: an epigenome-wide DNA methylation study
Creators: name: Zhu, Xiaojun
name: Jiang, Peiyue
name: Ying, Xia
name: Tang, Xueling
name: Deng, Youcai
name: Gao, Xinghong
name: Yang, Xiaofu
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1.
Trapping the carrier in the spin-locked MoS2 atomic valley by absorption of chiral L-cysteine
Creators: name: Bhattacharya, Susmita
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: This work, demonstrate enhanced valley contrasting spin-momentum locked chiral states at van der Waal interface of chiral L-cysteine and mono-atomically thin MoS2 placed at Si/SiO2 substrate at ambient condition. Helicity dependent photoluminescence and resonance Raman measurement highlights spin-locked transitions for chiral L-cysteine modified SL MoS2 at ambient condition. Selective adsorption of chiral L-cysteine dimer /cystine on monolayer MoS2, stabilizes the in-plane effective magnetic field due to Si/SiO2 substrate and blocks the intervalley spin relaxation. The observed polarisation efficiency will be useful for improving the functionality of valley-based light emitting diode (LEDs) and encoding information in logical devices.
description: 23 pages (6 figures, 3 sup figures)
Domain Model For European Poetry V 1.0
Creators: name: Curado Malta, Mariana
name: Bermudez-Sabel, Helena
Publisher: name: Zenodo
Year: 2018
Subjects: Domain Model
Metadata Application Profile
Linked Open Data
Semantic Web
European Poetry

description: This set of files (html + css and javascript) presents the Domain Model for the European poetry. This Domain Model (or data model) is a milestone in the process of development of a metadata application profile for the European Poetry.

A Domain Model is a conceptual model that is used to explicit the concepts that exist in a certain universe of discourse. The html file presents the entities and properties, the relations between these entities and the cardinalities of these relations.

The Domain Model v 1.0 comes from the validation of Domain Model v 0.3. This validation was done with the development of six use-cases.

The map https://goo.gl/O0mqhI presents the repertoires analysed and the phases of the analysis.

This work is framed in a Starting Grant research project Poetry Standardization and Linked Open Data: POSTDATA (ERC-2015-STG-679528), funded by European Research Council (ERC).
title: Bogue Banks Master Beach Nourishment Plan Project
titleType: AlternativeTitle
title: Endangered Species Act - Section 7 Consultation Biological Opinion SAW-2009-00293, Carteret County, Bogue Banks Master Beach Nourishment Plan, Carteret County, North Carolina
Creators: name: United States. National Marine Fisheries Service. Southeast Region
Publisher: name: United States. National Marine Fisheries Service. Southeast Region
Year: 2018

description: SERO-2017-00015
Adversarial reverse mapping of condensed-phase molecular structures: Chemical transferability
Creators: name: Stieffenhofer, Marc
name: Bereau, Tristan
name: Wand, Michael
Publisher: name: arXiv
Year: 2021
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Switching between different levels of resolution is essential for multiscale modeling, but restoring details at higher resolution remains challenging. In our previous study we have introduced deepBackmap: a deep neural-network-based approach to reverse-map equilibrated molecular structures for condensed-phase systems. Our method combines data-driven and physics-based aspects, leading to high-quality reconstructed structures. In this work, we expand the scope of our model and examine its chemical transferability. To this end, we train deepBackmap solely on homogeneous molecular liquids of small molecules, and apply it to a more challenging polymer melt. We augment the generator's objective with different force-field-based terms as prior to regularize the results. The best performing physical prior depends on whether we train for a specific chemistry, or transfer our model. Our local environment representation combined with the sequential reconstruction of fine-grained structures help reach transferability of the learned correlations.
description: 11 pages, 6 figures. arXiv admin note: text overlap with arXiv:2003.07753