cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM1 of LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription
Creators: name: Xiu, Bingqiu
name: Chi, Yayun
name: Liu, Lei
name: Chi, Weiru
name: Zhang, Qi
name: Chen, Jiajian
name: Guo, Rong
name: Si, Jing
name: Li, Lun
name: Xue, Jingyan
name: Shao, Zhi-Ming
name: Wu, Zhao-Hui
name: Huang, Shenglin
name: Wu, Jiong
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Additional file 1. Figure S1. LINC02273 correlates with poor prognosis in breast cancer. Figure S2. qPCR analysis of LINC02273 expression and genes closed to LINC02273 gene locus in LINC02273 KO cells. Figure S3. LINC02273 promotes breast cancer proliferation and metastasis but not cancer stemness. Figure S4. LINC02273 interacts with hnRNPL. Figure S5. LINC02273 transcriptionally activates AGR2 expression which was revealed by ChIRP. Figure S6. hnRNPL-LINC02273 complex promotes cancer metastasis through upregulating AGR2. Figure S7. Epigenetic regulation of modification at AGR2 promoter by hnRNPL was dependent on LINC02273. Figure S8. Targeting LINC02273 with ASO showed potential in mitigating breast cancer metastasis. Table S1. Patient characteristics of RNA microarray. Table S2. CPAT prediction of LINC02273. Table S3. CPC prediction of LINC02273. Table S4. Baseline clinicopathological characteristics of patients according to LINC02273 expression. Table S5. Univariant COX regression analyses of RFS in BC patients. Table S6. Multivariant COX regression analyses of RFS in BC patients. Table S7. LINC02273 knockout neckties. Table S8. MS result of LINC02273 RNA pull-down. Table S9. Baseline clinicopathological characteristics of patients according to AGR2 expression. Table S10. Multivariant COX regression analyses of RFS in BC patients. Table S11. Probes used in this study. Table S12. Primers used in this study. Table S13. shRNA, siRNA, CRISPR, and ASOs.
Team Software Process℠ (TSP℠) Body of Knowledge (BOK)
Creators: name: Watts S. Humphrey
name: Chick, Timothy A.
name: Nichols, William R.
name: Pomeroy-Huff, Marsha
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: The Team Software Process Body of Knowledge (TSP BOK) was drafted to define the fundamental knowledge and skills that set TSP-trained individuals apart from other software professionals. It helps individual practitioners to assess and improve their own skills, provides employers with an objective baseline for assessing the process improvement skills and capabilities of their development team members, and guides academic institutions that want to incorporate TSP into their software and other engineering courses or curricula. The TSP BOK also facilitates the development of TSP certification programs that are based on a well-established standard set of knowledge and skills.
Análisis de impacto regulatorio resolución CREG 101 001 de 2022
Creators: name: Quintero Bejarano, Leonardo
Publisher: name: Universidad Externado de Colombia
Year: 2022
Subjects: subject: Asistencia técnica
subject: Asistencia pública
subject: Industria energética
subject: AMI
subject: CREG 038
subject: AIN
subject: GIDI
subject: Infraestructura de medición avanzada

description: El presente estudio comprendió el desarrollo del AIN para la resolución CREG 101 001 DE 2022 donde se evalué el impacto económico que tendrá para el OR, Comercializador y usuarios, cuyo abordaje metodológico implicó según Sabino (2015), la investigación documental, antes conocida como investigación bibliográfica, es una investigación teórica formal y abstracta, en el sentido de que la información está contenida en fuentes documentales como libros, revistas, periódicos, se recopila, registra, analiza e interpreta, texto, discos, CDs, sentencias, expedientes, leyes, códigos, reglamentos, compilaciones, bases de actos jurídicos, entre otros, tal como se practica en este estudio de la AIN. En este sentido, la unidad de estudio o unidad de análisis está referida al contexto, característica o variable que se desea investigar. Es así como la unidad puede estar dada por una persona, un grupo, un objeto u otro que contengan claramente los eventos a investigar. Es así como en la presente investigación la unidad de estudio está constituida por la teoría sobre la que se desarrolla y recopila toda la información, sobre el análisis de impacto normativo (AIN), Infraestructura de Medición Avanzada (AMI), Resolución CREG 101 001 de 2022.
description: The present study included the development of the AIN for the CREG resolution 101 001 OF 2022 where the economic impact that it will have for the OR, Marketer and users was evaluated, whose methodological approach implied, according to Sabino (2015), documentary research, formerly known as research bibliographic, is a formal and abstract theoretical research, in the sense that the information is contained in documentary sources such as books, magazines, newspapers, is collected, recorded, analyzed and interpreted, text, records, CDs, sentences, files, laws, codes, regulations, compilations, bases of legal acts, among others, as practiced in this AIN study. In this sense, the unit of study or unit of analysis refers to the context, characteristic or variable to be investigated. This is how the unit can be given by a person, a group, an object or another that clearly contains the events to be investigated. This is how in the present investigation the study unit is constituted by the theory on which all the information is developed and compiled, on the regulatory impact analysis (AIN), Advanced Measurement Infrastructure (AMI), CREG Resolution 101 001 of 2022.
MAJORITARIANISM AND ITS IMPACT ON EFFECTIVE COLLECTIVE BARGAINING
Creators: name: XAVIER KNIGHT
name: WILFRED I. UKPERE
Publisher: name: Zenodo
Year: 2024
Subjects: Majoritarianism, Collective Bargaining, Majority Trade Unions, Minority Trade Unions, Organisational Rights.

description: Abstract

Within an employment context, majoritarianism necessitates that all legally enforceable organisational rights, including collective bargaining, is only fully enjoyed by majority trade unions in the workplace. Consequently, minority or lesser unions are excluded from collective bargaining processes. This paper’s objective was to determine possible restrictions that majoritarianism has on effective collective bargaining in South Africa. To realise this objective, a qualitative phenomenological research design was adopted, where semi-structured interviews were conducted to collect data from research participants. In total, twelve research participants contributed to the study. Results of the present study revealed that participants attribute union rivalry to majoritarianism, where a negative organisational culture emerges characterised by superiority and inferiority complexes, leading to the loss of valuable contributions by minority unions in collective bargaining processes. It is recommended that organisations increase employee participation and inclusivity in the workplace, characterised by broader organisational engagements and a neutral management approach to union relations. Moreover, all trade unions should adopt a macro-focused approach to collective bargaining, considering the sustainability of both the organisation and individual employment prospects.
The Cosmic Horizon
Creators: name: Melia, Fulvio
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The cosmological principle, promoting the view that the universe is homogeneous and isotropic, is embodied within the mathematical structure of the Robertson-Walker (RW) metric. The equations derived from an application of this metric to the Einstein Field Equations describe the expansion of the universe in terms of comoving coordinates, from which physical distances may be derived using a time-dependent expansion factor. These coordinates, however, do not explicitly reveal properties of the cosmic spacetime manifested in Birkhoff's theorem and its corollary. In this paper, we compare two forms of the metric--written in (the traditional) comoving coordinates, and a set of observer-dependent coordinates--first for the well-known de Sitter universe containing only dark energy, and then for a newly derived form of the RW metric, for a universe with dark energy and matter. We show that Rindler's event horizon--evident in the co-moving system--coincides with what one might call the "curvature horizon" appearing in the observer-dependent frame. The advantage of this dual prescription of the cosmic spacetime is that with the latest WMAP results, we now have a much better determination of the universe's mass-energy content, which permits us to calculate this curvature with unprecedented accuracy. We use it here to demonstrate that our observations have probed the limit beyond which the cosmic curvature prevents any signal from having ever reached us. In the case of de Sitter, where the mass-energy density is a constant, this limit is fixed for all time. For a universe with a changing density, this horizon expands until de Sitter is reached asymptotically, and then it too ceases to change.
description: Accepted for publication in MNRAS
Suzaku Observation of the Anomalous X-ray Pulsar CXOU J164710.2--455216
Creators: name: Naik, Sachindra
name: Dotani, Tadayasu
name: Kawai, Nobuyuki
name: Kokubun, Motohide
name: Anada, Takayasu
name: Morii, Mikio
name: Mihara, Tatehiro
name: Enoto, Teruaki
name: Kawaharada, Madoka
name: Murakami, Toshio
name: Nakagawa, Yujin E.
name: Takahashi, Hiromitsu
name: Terada, Yukikatsu
name: Yoshida, Atsumasa
Publisher: name: arXiv
Year: 2007
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Suzaku TOO observation of the anomalous X-ray pulsar CXOU J164710.2-455216 was performed on 2006 September 23--24 for a net exposure of 38.8 ks. During the observation, the XIS was operated in 1/8 window option to achieve a time resolution of 1 s. Pulsations are clearly detected in the XIS light curves with a barycenter corrected pulse period of 10.61063(2) s. The XIS pulse profile shows 3 peaks of different amplitudes with RMS fractional amplitude of ~11% in 0.2--6.0 keV energy band. Though the source was observed with the HXD of Suzaku, the data is highly contaminated by the nearby bright X-ray source GX 340+0 which was in the HXD field of view. The 1-10 keV XIS spectra are well fitted by two blackbody components. The temperatures of two blackbody components are found to be 0.61+/-0.01 keV and 1.22+/-0.06 keV and the value of the absorption column density is 1.73+/-0.03 x 10^{22} atoms cm^{-2}. The observed source flux in 1-10 keV energy range is calculated to be 2.6 x 10^{-11} ergs cm^{-2} s^{-1} with significant contribution from the soft blackbody component (kT = 0.61 keV). Pulse phase resolved spectroscopy of XIS data shows that the flux of the soft blackbody component consists of three narrow peaks, whereas the flux of the other component shows a single peak over the pulse period of the AXP. The blackbody radii changes between 2.2-2.7 km and 0.28-0.38 km (assuming the source distance to be 5 kpc) over pulse phases for the soft and hard components, respectively. The details of the results obtained from the timing and spectral analysis is presented.
description: 16 pages, 9 figures, Accepted for publication in Publications of the Astronomical Society of Japan (PASJ)
Team Software Process (TSP) Coach Mentoring Program Guidebook, Version 2.0
Creators: name: Chick, Timothy A.
name: McHale, James
name: Nichols, William R.
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: This guidebook explains the mentoring process required to become an SEI-Certified Team Software Process (TSP) Associate Coach, SEI-Certified TSP Coach, or SEI-Certified TSP Mentor Coach. It also defines the structure and format of the mentor and mentee relationship and explains the steps and evaluation criteria for becoming a coach. Refer to the Team Software Process (TSP) Coach Certification Guidebook (CMU/SEI-2013-SR-025) for a description of the required steps and evaluation criteria for becoming an SEI-Certified TSP Associate Coach, Coach, or Mentor Coach.
The Conformal Characters
Creators: name: Bourget, Antoine
name: Troost, Jan
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We revisit the study of the multiplets of the conformal algebra in any dimension. The theory of highest weight representations is reviewed in the context of the Bernstein-Gelfand-Gelfand category of modules. The Kazhdan-Lusztig polynomials code the relation between the Verma modules and the irreducible modules in the category and are the key to the characters of the conformal multiplets (whether finite dimensional, infinite dimensional, unitary or non-unitary). We discuss the representation theory and review in full generality which representations are unitarizable. The mathematical theory that allows for both the general treatment of characters and the full analysis of unitarity is made accessible. A good understanding of the mathematics of conformal multiplets renders the treatment of all highest weight representations in any dimension uniform, and provides an overarching comprehension of case-by-case results. Unitary highest weight representations and their characters are classified and computed in terms of data associated to cosets of the Weyl group of the conformal algebra. An executive summary is provided, as well as look-up tables up to and including rank four.
description: 41 pages, many figures
El paradigma del interés general de las comunidades en zona de influencia del transporte de hidrocarburos
Creators: name: Molina Moreno, Marvin Hernando
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Transporte
subject: Economía
subject: Servicios públicos
subject: Área de influencia
subject: Certificado de residencia
subject: Mano de obra
subject: Comunidades
subject: Líneas de transporte

description: Existe un interés general de las comunidades en las áreas de influencia localizadas en las líneas de transporte de hidrocarburos, las cuales constantemente se encuentran en dificultades o conflictos de carácter social, económico y laboral con las compañías que operan los proyectos. Encontrado algunas falencias en la regulación existente, con factores que tienen relación directa con los intereses de las comunidades; como la determinación de las diferentes áreas de influencia, la certificación de residencia que tiene una relación directa con la mano de obra calificada y no calificada, el avaluó de las tierras, la desvaloración de los predios, el trabajo y cooperación con las Juntas de Acción Comunal, entre otros. Este documento tiene como propósito visualizar algunos de los escenarios y circunstancias que se presentan en terreno de manera permanente, donde nos permita proponer soluciones dirigidas a facilitar los proyectos desarrollados de interés general de la industria del y transporte de hidrocarburos.
description: There is a general interest of the communities in the areas of influence located in the hydrocarbon transport lines, which constantly find themselves in difficulties or conflicts of a social, economic and labor nature with the companies that operate the projects. Found some shortcomings in the existing regulation, with factors that are directly related to the interests of the communities; such as the determination of the different areas of influence, the certification of residence that has a direct relationship with skilled and unskilled labor, the appraisal of land, the devaluation of land, work and cooperation with the Community Action Boards, among others. This document aims to visualize some of the scenarios and circumstances that arise in the field on a permanent basis, where it allows us to propose solutions aimed at facilitating the projects developed of general interest of the hydrocarbon and transport industry.
[Letter, Emma Crosby to Eliza Douse, March 11, 1874]
Creators: name: Crosby, Emma, 1849-1926
Publisher: name: The University of British Columbia
Year: 2013

description: Emma Crosby, Hamilton, to Eliza Douse [Mother]. Informs her mother that Mr. Crosby has marked May 1st as the latest date for their departure. Requests her mother have household linens sewn for her, of the same refinement as she is accustomed to in Ontario. Asks for twenty or thirty dollars as well, as she has not yet been paid up.
Supporting_Information_for_Physiological_Factors_Influencing_Female_Fertility_In_Birds from Physiological factors influencing female fertility in birds
Creators: name: Assersohn, Katherine
name: Brekke, Patricia
name: Hemmings, Nicola
Publisher: name: The Royal Society
Year: 2021
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Health Care
subject: Diseases
subject: 111706 Epidemiology
subject: FOS: Health sciences

description: Detailed methods and results for the systematic literature search analysis in “Physiological factors influencing female fertility in birds”. Methods include a PRISMA diagram showing the literature search and categorisation process, and a table detailing the specific criteria used to categorise papers.
Team Software Process (TSP) Coach Mentoring Program Guidebook Version 1.1
Creators: name: Chick, Timothy A.
name: Cannon, Robert
name: McHale, James
name: Nichols, William R.
name: Pomeroy-Huff, Marsha
name: Welch, Jefferson
name: Willett, Alan
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: This guidebook is designed to explain the steps for becoming an SEI-Certified Team Software Process (TSP) Coach or SEI-Certified TSP Mentor Coach, with emphasis on guiding individuals through the mentoring process. This guidebook defines the structure and format of the mentor and provisional coach relationship, and explains the process steps and evaluation criteria for becoming an SEI-Certified TSP Coach or Mentor Coach.
[Letter, Emma Crosby to Eliza Douse, March 13, 1874]
Creators: name: Crosby, Emma, 1849-1926
Publisher: name: The University of British Columbia
Year: 2013

description: Emma Crosby, Hamilton, to Eliza Douse [Mother]. Emma thanks her parents for their money and trouble. Discusses forthcoming plans and shipping of household items to British Columbia. Expresses her desire that her parents speak to her brother George as he believes her decision is grieving their parents.
First Sunyaev-Zel'dovich mapping with the NIKA2 camera: Implication of cluster substructures for the pressure profile and mass estimate
Creators: name: Ruppin, F.
name: Mayet, F.
name: Pratt, G. W.
name: Adam, R.
name: Ade, P.
name: André, P.
name: Arnaud, M.
name: Aussel, H.
name: Bartalucci, I.
name: Beelen, A.
name: Benoît, A.
name: Bideaud, A.
name: Bourrion, O.
name: Calvo, M.
name: Catalano, A.
name: Comis, B.
name: De Petris, M.
name: Désert, F. -X.
name: Doyle, S.
name: Driessen, E. F. C.
name: Goupy, J.
name: Kramer, C.
name: Lagache, G.
name: Leclercq, S.
name: Lestrade, J. -F.
name: Macías-Pérez, J. F.
name: Mauskopf, P.
name: Monfardini, A.
name: Perotto, L.
name: Pisano, G.
name: Pointecouteau, E.
name: Ponthieu, N.
name: Revéret, V.
name: Ritacco, A.
name: Romero, C.
name: Roussel, H.
name: Schuster, K.
name: Sievers, A.
name: Tucker, C.
name: Zylka, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The complete characterization of the pressure profile of high-redshift galaxy clusters, from their core to their outskirts, is a major issue for the study of the formation of large-scale structures. It is essential to constrain a potential redshift evolution of both the slope and scatter of the mass-observable scaling relations used in cosmology studies based on cluster statistics. In this paper, we present the first thermal Sunyaev-Zel'dovich (tSZ) mapping of a cluster from the sample of the NIKA2 SZ large program that aims at constraining the redshift evolution of cluster pressure profiles and the tSZ-mass scaling relation. We have observed the galaxy cluster PSZ2 G144.83+25.11 at redshift $z=0.58$ with the NIKA2 camera, a dual-band (150 and 260 GHz) instrument operated at the IRAM 30-meter telescope. We identify a thermal pressure excess in the south-west region of PSZ2 G144.83+25.11 and a high redshift sub-millimeter point source that affect the intracluster medium (ICM) morphology of the cluster. The NIKA2 data are used jointly with tSZ data acquired by the MUSTANG, Bolocam and $Planck$ experiments in order to non-parametrically set the best constraints on the electronic pressure distribution from the cluster core ($\rm{R} \sim 0.02 \rm{R_{500}}$) to its outskirts ($\rm{R} \sim 3 \rm{R_{500}} $). We investigate the impact of the over-pressure region on the shape of the pressure profile and on the constraints on the integrated Compton parameter $\rm{Y_{500}}$. A hydrostatic mass analysis is also performed by combining the tSZ-constrained pressure profile with the deprojected electronic density profile from XMM-$Newton$. This allows us to conclude that the estimates of $\rm{Y_{500}}$ and $\rm{M_{500}}$ obtained from the analysis with and without masking the disturbed ICM region differ by 65 and 79% respectively. (abridged)
La revitalisation linguistique 2.0 : Les technologies de l'information et la communication dans les projets de revitalisation des langues autochtones au Canada
Creators: name: Spry, Zoé
Publisher: name: My University
Year: 2017

description: Depuis les années 1990, la revitalisation linguistique est présentée comme moyen de combattre la lente disparition des langues autochtones et minoritaires à travers le monde. Au même moment, l’ère des technologies de l’information et des communications a fait un élan important, permettant le développement de nouveaux outils de préservation et de promotion des langues. Les communautés autochtones au Canada ont profité de ces nouveaux outils technologiques afin de développer des projets de revitalisation innovateurs, tels que le site eastcree.org (2001) et First Voices (2004), permettant de rendre plus accessibles les ressources linguistiques et didactiques. Aujourd’hui, le climat politique canadien semble plus favorable que jamais à la revitalisation des langues autochtones; un changement d’attitude qui suit la publication en 2015 du Rapport de la Commission de vérité et réconciliation qui a émis plusieurs recommandations touchant les langues autochtones. En 2017, le gouvernement du Canada a accru son appui financier aux projets de préservation des langues autochtones au travers de l’Initiative des langues autochtones et pourrait bientôt adopter une première disposition législative fédérale pour la protection des langues autochtones. Ce mémoire présente les présupposées et les approches proposées pour la revitalisation des langues, la conceptualisation des projets par le moyen des technologies de l’information et tente de tirer des enseignements pour l’étude de la revitalisation et la transmission intergénérationnelle au Canada. Les projets du site eastcree.org, menés dans la région de la baie James au Québec, et First Voices, menés dans les communautés de langue tagish au Yukon et en Colombie-Britannique, représentent de grands efforts pour que les communautés impliquées puissent s’approprier l’outil développé, dans les deux cas, soit une base de données de ressources linguistiques, serve la communauté. Le manque de financement pour les projets linguistiques ainsi que la crainte de plusieurs communautés autochtones de voir leurs ressources linguistiques être appropriées par d’autres groupes font en sorte que les ressources de revitalisation linguistique sont inégales d’une communauté à l’autre. Ces défis démontrent qu’un exercice de planification stratégique des ressources linguistiques en ligne est de mise pour prévenir la disparition de leurs langues. Mots-clés : revitalisation linguistique, langues autochtones, technologies de l’information, préservation de la langue, langues menacées
Inteligencia artificial en la construcción del estado de la técnica en el sistema de patentes
Creators: name: Rodriguez Rodriguez, Nicolas
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Aprendizaje automatico
subject: Tecnología y derecho
subject: Actos jurídicos
subject: Patentes
subject: Inteligencia artificial
subject: Machine learning
subject: Redes neuronales
subject: Estado de la técnica

description: Los documentos de patentes se caracterizan por tener un nivel alto de tecnicidad en su contenido, de ahí que, la tarea de recuperar información en un determinado campo de la ciencia pueda resultar en una compleja labor. Por esta razón, el presente texto tiene como objetivo brindar una explicación descriptiva en torno a la implementación alternativas tecnológicas basadas en Inteligencia Artificial para la recuperación de información relacionada con documentos de patentes en la construcción del estado de la técnica, todo esto, con el fin de dar a conocer al lector una serie de herramientas basadas en estas tecnológicas que coadyuven el proceso de investigación, permitiendo la obtención de resultados más precisos
description: Patent documents are characterized by a high level of technicality in their content, hence, the task of retrieving information in a particular field of science can be a complex task. For this reason, this text aims to provide a descriptive explanation about the implementation of technological alternatives based on Artificial Intelligence for the retrieval of information related to patent documents in the construction of the prior art, all this, in order to inform the reader about a series of tools based on these technologies that assist the research process, allowing the obtaining of more accurate results.
[Letter, Emma Crosby to Eliza Douse, May 9, 1874]
Creators: name: Crosby, Emma, 1849-1926
name: Crosby, Thomas, 1840-1914
Publisher: name: The University of British Columbia
Year: 2013

description: Emma Crosby, Waukegan [Illinois], to Eliza Douse [Mother]. Briefly describes the beginning of her journey, and assures her parents that they should not feel anxious. Mr. Crosby adds a note on the last page, dated May 18th, stating that the journey was going well and that he had preached twice that day.
Team Software Process (TSP) Coach Certification Guidebook
Creators: name: Chick, Timothy A.
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: This guidebook explains the process required to become an SEI-Certified Team Software Process (TSP) Associate Coach, SEI-Certified TSP Coach, or SEI-Certified TSP Mentor Coach. It describes the entry requirements, certification process steps, and performance evaluation components that must be satisfied. Please refer to the Team Software Process (TSP) Coach Mentoring Program Guidebook, Version 2.0 (CMU/SEI-2013-SR-024) for a comprehensive description of the mentorship component of the certification process. Mentorship is one of the key requirements that must be met in order to become an SEI-Certified TSP Coach. Mentoring also plays a role in the certification process for SEI-Certified TSP Associate Coaches and SEI-Certified TSP Mentor Coaches.
Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of Vaccine Design
Creators: name: Xia, Xuhua
Publisher: name: My University
Year: 2021
Subjects: COVID-19
S-2P
SARS-CoV-2
cleavage
hydrophobicity
isoelectric point
protein structure
spike protein
vaccine
COVID-19 Vaccines
Humans
Membrane Fusion
Mutation
Protein Binding
Protein Domains
Protein Stability
Receptors, Virus
Spike Glycoprotein, Coronavirus
Virus Internalization

description: The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection. Both Pfizer/BioNTech's BNT162b2 and Moderna's mRNA-1273 vaccine candidates are based on stabilized mRNA encoding prefusion SARS-2-S that can be produced after the mRNA is delivered into the human cell and translated. SARS-2-S is cleaved into S1 and S2 subunits, with S1 serving the function of receptor-binding and S2 serving the function of membrane fusion. Here, I dissect in detail the various domains of SARS-2-S and their functions discovered through a variety of different experimental and theoretical approaches to build a foundation for a comprehensive mechanistic understanding of how SARS-2-S works to achieve its function of mediating cell entry and subsequent cell-to-cell transmission. The integration of structure and function of SARS-2-S in this review should enhance our understanding of the dynamic processes involving receptor binding, multiple cleavage events, membrane fusion, viral entry, as well as the emergence of new viral variants. I highlighted the relevance of structural domains and dynamics to vaccine development, and discussed reasons for the spike protein to be frequently featured in the conspiracy theory claiming that SARS-CoV-2 is artificially created.
La responsabilidad patrimonial extracontractual del estado a título de falla en el servicio, por indebida prestación del proceso de desminado sobre las jurisdicciones territoriales declaradas “libres de minas antipersonal”
Creators: name: Rodríguez Peña, Silvia María
Publisher: name: Universidad Externado de Colombia
Year: 2022
Subjects: subject: Responsabilidad contractual
subject: Patrimonio - Derecho
subject: Servicios públicos
subject: Responsabilidad patrimonial extracontractual del Estado
subject: Falla del servicio
subject: Confianza legítima
subject: Mina antipersonal
subject: Garantías derivadas del desminado

description: En 2016 la Presidencia de Colombia en declaración pública señaló al Municipio de San Vicente de Chucurí – Santander, como territorio “libre de Minas Antipersonal” - M.A.P., como consecuencia de un proceso de desminado humanitario, excediendo ampliamente el margen de cobertura de la garantía del proceso de desminado, el cual recae únicamente sobre áreas o polígonos predeterminados, exponiendo a la administración pública a litigios contencioso administrativos por responsabilidad patrimonial extracontractual del Estado a título de falla en el servicio, en aquellos eventos de víctimas de M.A.P. en las zonas declaradas libres, en contravía de los criterios técnico-científicos propios del proceso de desminado.
description: In 2016, the Presidency of Colombia, in a public declaration, designated the Municipality of San Vicente de Chucurí - Santander as a territory free of Antipersonnel Mines (M.A.P.) as a consequence of a humanitarian demining process, a declaration that greatly exceeded the margin of coverage of the guarantee of a demining process, which falls and is executed only on predetermined areas or polygons. Thus, exposing the public administration to contentious-administrative litigation for noncontractual patrimonial liability of the State as a service failure in those events of victims of M.A.P. in areas declared free, contrary to the technical-scientific criteria of the demining process.
Lepton mixing and the charged-lepton mass ratios
Creators: name: Jurciukonis, D.
name: Lavoura, L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We construct a class of renormalizable models for lepton mixing that generate predictions given in terms of the charged-lepton mass ratios. We show that one of those models leads, when one takes into account the known experimental values, to almost maximal CP-breaking phases and to almost maximal neutrinoless double-beta decay. We study in detail the scalar potential of the models, especially the bounds imposed by unitarity on the values of the quartic couplings.
description: 39 pages, 9 figures; revised version addressed the criticism of the editor, matches now the published version
Traitier de Cyrurgie
Creators: name: Albucasis
name: Albucasis
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Langue et littérature françaises médiévales

description: Texte en français médiéval. Date de composition : mil. 13e s. (1234 - 1266), domaine : didactique, genre : traité, forme : prose
description: Bibliographic citation: Albucasis, Traitier de Cyrurgie, édité par David Trotter, Tübingen, 2005. Publié en ligne par la Base de français médiéval, http://catalog.bfm-corpus.org/ChirAlbT. Dernière révision le 2018-07-26.
À la guerre, le silence est d‘or Une analyse comparative de La guerre n‘a pas un visage de femme (1985) et de Les Cercueils de zinc (1989) de Svetlana Alexievitch
Creators: name: Couture, Dominic
Publisher: name: My University
Year: 2021
Subjects: Svetlana Alexievitch
Les Cercueils de zinc
La guerre n‘a pas un visage de femme
normes sociales
vétérans
Union soviétique
silence
État
mutisme individuel

description: Cet article analyse l‘importance du silence en tant que th me litt raire dans les romans Les Cercueils de zinc (1989) et La guerre n‘a pas un visage de femme (1985) par Svetlana Alexievitch Ces romans d montrent comment les v t rans de l‘Union sovi tique qui ont combattu lors de la Deuxième Guerre mondiale et de la guerre en Afghanistan, ainsi que leurs proches, ont été confrontés à une culture du silence. On les réprimait dans leur besoin de parler de leurs exp riences, ainsi que dans leur d sir d‘être reconnu pour avoir combattu pour leur patrie Cet article labore trois types de silence que l‘on peut retrouver dans les deux œuvres d‘Alexievitch : le silence étatique, le silence sociétal et le silence individuel.
[Letter, Emma Crosby to Eliza Douse, May 12, 1874]
Creators: name: Crosby, Emma, 1849-1926
Publisher: name: The University of British Columbia
Year: 2013

description: Emma Crosby, Union Pacific Railroad, Nebraska, to Eliza Douse [Mother]. Expresses regrets she couldn't stay longer in Waukegan and describes the journey as pleasant. Describes the prairies, and notes the anticipated date of arrival in Victoria.
T-Check in Technologies for Interoperability: Web Services and Security—Single Sign-On
Creators: name: Wrage, Lutz
name: Soumya  Simanta
name: Lewis, Grace A.
name: Jaspan, Saul
Publisher: name: Carnegie Mellon University
Year: 2008
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences

description: A single sign-on (SSO) solution is intended to provide a single authentication point for a set of Web services. The SSO solution for-wards the necessary authentication information to the Web services, which in turn authenticate the end user to legacy systems that implement the Web services' functionality. This technical note presents the results of applying the T-Check approach in an initial investigation of two Web services standards, WS-Security and SAML, to create an SSO solution that works inside a single organization. This approach involves (1) formulating hypotheses about the technology and (2) examining these hypotheses against specific criteria through hands-on experimentation. The outcome of this two-stage approach is that the hypotheses are either fully or partially sustained or refuted. In this report, four hypotheses-based on claims found in experience reports and on vendor Web sites-are examined: (1) it is possible to implement SSO for the two Web services using SAML and WS-Security; (2) it is fairly easy to implement a basic SSO solution; (3) the SSO solution will not have a major impact on the runtime behavior of the system; and (4) the SSO solution can provide the required access control. The first three hypotheses were sustained; it was not necessary to implement the fourth one to list options for adding access control.
Les pratiques d’intervention auprès des femmes survivantes de violence lors de conflits armés : Le cas des femmes congolaises dans la région d’Ottawa.
Creators: name: Congera, Béatrice
Publisher: name: My University
Year: 2022

description: La violence envers les femmes lors des conflits armés est une problématique d’envergure qui est peu représentée dans le domaine de l’intervention sociale au Canada. Ce type de violence devient de plus en plus courante dans le champ de l’immigration. Les femmes ayant vécu la violence en temps de conflits armés immigrent dans les pays jugés sécuritaires pour trouver refuge. On constate que souvent, ce sont les femmes perçues comme étant vulnérables pendant des périodes de guerre qui sont prises pour cible par les instigateurs de violence. Dans ce travail, on analysera l’accompagnement des intervenants sociaux dans le pays d’accueil (Canada) dans le processus d’intégration sociale des femmes survivantes de violence lors des conflits armés avec la question de recherche suivante : les méthodes d’intervention auprès des femmes survivantes de violence lors des conflits armés répondent-elles aux besoins émotionnels liés aux traumatismes que peuvent rencontrer ces femmes dans leur processus d’intégration au Canada ? Par le biais d’entrevues semi-dirigées, cette recherche démontre clairement que les services d’aide auprès des femmes survivantes de violence lors des conflits ne répondent pas assez aux besoins émotionnels liés au trauma des femmes survivantes de violence lors des conflits armés. On voit aussi certaines limites que rencontrent les intervenants lors de leurs interventions auprès des femmes survivantes de ce type de violence tels que le sous-financement des bailleurs des fonds, et le manque de formation continue sur la question. Afin, cette recherche reconnaît le travail exceptionnel qu’effectuent les intervenants afin d’assurer le bien-être émotionnel des survivantes et l’accompagnement des survivantes de leur accueil et intégration au Canada. Mots clés : Violence, conflits armés, intervention, intégration, traumatisme.
Las dos caras de El Bronx : análisis de los instrumentos de planificación para el fenómeno de habitabilidad de calle y sus implicaciones en la ciudad a partir de la intervención de El Bronx
Creators: name: González Peña, Olga Lucía
name: Mateus Avila, Johana Alexandra
Publisher: name: Universidad Externado de Colombia
Year: 2023
Subjects: subject: Territorio nacional
subject: Demografía
subject: Calidad de vida
subject: Ciudadano habitante de calle
subject: Planificación
subject: Desarrollo
subject: Territorio
subject: Desigualdad

description: La presente investigación hace referencia al análisis especializado de los instrumentos de planificación en Bogotá que dieron lugar a la intervención de El Bronx en el 2016, las decisiones que se tomaron y su repercusión en la transformación del territorio. Para ello, se adoptaron elementos de la metodología BIT PASE con el fin de identificar y comprender el Fenómeno de Habitabilidad de Calle, el cual se abordó tras la presión que ejercen los actores en las instituciones y la implementación de los planes de renovación urbana para el crecimiento de la ciudad, sin embargo, no se ha tenido en cuenta el sentir y la necesidad del ciudadano habitante de calle (CHC) que hace parte del territorio, por consiguiente, las intervenciones carecen de enfoque diferencial, inclusión, gestión social y sostenibilidad.
description: The present investigation refers to the specialized analysis of the planning instruments in Bogotá that gave rise to the intervention of the Bronx in 2016, the decisions that were made there, and how they affected the transformation of the territory adopting elements of the BIT PASE methodology for the identification and understanding of the Street Habitability Phenomenon, concluding that this has been urban approached after the pressure exerted by the actors in the institutions and the implementation of the renovation plans for the growth of the city and has not been taken into account the feel and the need of the CHC that is part of the territory, therefore, the interventions lack a differential approach, inclusion, social management and sustainability.
The diachromatic number of digraphs
Creators: name: Araujo-Pardo, Gabriela
name: Montellano-Ballesteros, Juan José
name: Olsen, Mika
name: Rubio-Montiel, Christian
Publisher: name: arXiv
Year: 2017
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C15, 05C20

description: We consider the extension to directed graphs of the concept of achromatic number in terms of acyclic vertex colorings. The achromatic number have been intensely studied since it was introduced by Harary, Hedetniemi and Prins in 1967. The dichromatic number is a generalization of the chromatic number for digraphs defined by Neumann-Lara in 1982. A coloring of a digraph is an acyclic coloring if each subdigraph induced by each chromatic class is acyclic, and a coloring is complete if for any pair of chromatic classes $x,y$, there is an arc from $x$ to $y$ and an arc from $y$ to $x$. The dichromatic and diachromatic numbers are, respectively, the smallest and the largest number of colors in a complete acyclic coloring. We give some general results for the diachromatic number and study it for tournaments. We also show that the interpolation property for complete acyclic colorings does hold and establish Nordhaus-Gaddum relations.
description: 12 pages
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 835
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 835, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 835, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Metabolic glycan labeling immobilizes dendritic cell membrane and enhances antitumor efficacy of dendritic cell vaccine.
Creators: name: Han, Joonsu
name: Bhatta, Rimsha
name: Liu, Yusheng
name: Bo, Yang
name: Elosegui-Artola, Alberto
name: Wang, Hua
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: classificationCode: Tumour Biology
subject: Tumour Biology
classificationCode: Signalling & Oncogenes
subject: Signalling & Oncogenes
classificationCode: Developmental Biology
subject: Developmental Biology
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology
classificationCode: Microfabrication & Bioengineering
subject: Microfabrication & Bioengineering
classificationCode: Structural Biology & Biophysics
subject: Structural Biology & Biophysics
classificationCode: Cell Biology
subject: Cell Biology
classificationCode: Imaging
subject: Imaging

description: Dendritic cell (DC) vaccine was among the first FDA-approved cancer immunotherapies, but has been limited by the modest cytotoxic T lymphocyte (CTL) response and therapeutic efficacy. Here we report a facile metabolic labeling approach that enables targeted modulation of adoptively transferred DCs for developing enhanced DC vaccines. We show that metabolic glycan labeling can reduce the membrane mobility of DCs, which activates DCs and improves the antigen presentation and subsequent T cell priming property of DCs. Metabolic glycan labeling itself can enhance the antitumor efficacy of DC vaccines. In addition, the cell-surface chemical tags (e.g., azido groups) introduced via metabolic glycan labeling also enable in vivo conjugation of cytokines onto adoptively transferred DCs, which further enhances CTL response and antitumor efficacy. Our DC labeling and targeting technology provides a strategy to improve the therapeutic efficacy of DC vaccines, with minimal interference upon the clinical manufacturing process.
Superradiance and Instability of Black Holes
Creators: name: Kodama, Hideo
Publisher: name: arXiv
Year: 2007
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We discuss the relation between the superradiance phenomenon and the instability of rotating black holes in higher dimensions. In particular, we point out that the superradiant instability of a massless scalar field around a simply rotating Kerr-adS black hole implies the gravitational instability of that black hole for tensor-type perturbations.
description: References added. 13 pages, 3 figures. A talk given at ICGA8 to be published in Prog. Theor. Phys. Supplement
Effect of fly ash on the potential alkali silica reaction of ferronickel slag aggregate
Creators: name: Saha, ashish Kumer
name: Sarkar, Prabir Kumar
Publisher: name: figshare
Year: 2021
Subjects: subject: 90503 Construction Materials
subject: FOS: Civil engineering

description: Ferronickel slag (FNS) is generated as a by-product during the production of ferronickel. The rapid cooling process of the slag may lead to the formation of amorphous silica. Therefore, partial replacement of sand with nickel slag aggregate has potential to show expansion due to alkali silica reaction (ASR). The present study evaluates the effect of fly ash as a supplementary cementing material (SCM) to mitigate this deleterious expansion. Fly ash was used as 10%, 20% and 30% of the binder in order to investigate its effect on the reduction of ASR. The results of accelerated mortar bar test (AMBT) show that 10% replacement of cement by fly ash was unable to reduce expansion below the required level. Furthermore, use of 20% fly ash reduced the expansion by 45% compared to 10% fly ash samples, but still the expansion level of the samples was within the category of slowly reactive aggregate according to AS 1141.60.1-14. However, use of 30% fly ash reduced ASR expansion below the 10-day and 21-day limits of the standard. It was found that expansion did not increase for the extended period of test in the samples containing 30% fly ash. The microstructural observation was carried out to confirm the effectiveness of fly ash to mitigate this expansion.