cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: Table S1. of Comparison of the association of mammographic density and clinical factors with ductal carcinoma in situ versus invasive ductal breast cancer in Korean women
Creators: name: Hyeonyoung Ko
name: Jinyoung Shin
name: Lee, Jeong
name: Nam, Seok
name: Nguyen, Tuong
name: Hopper, John
name: Song, Yun-Mi
Publisher: name: figshare
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Influence of the method of subjects recruitment on the association of the clinical, reproductive, and mammographic density characteristics with invasive ductal carcinoma and ductal carcinoma in situ. Table S2 Association of body mass index with breast cancer according to menopausal status. (DOCX 23 kb)
Additional file 3: of A partially supervised physical activity program for adult and adolescent survivors of childhood cancer (SURfit): study design of a randomized controlled trial [NCT02730767]
Creators: name: Rueegg, Corina
name: Kriemler, Susi
name: Zuercher, Simeon
name: Schindera, Christina
name: Renner, Andrea
name: Hebestreit, Helge
name: Meier, Christian
name: Eser, Prisca
name: Weid, Nicolas Von Der
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Measures and methods within SURfit at different time points. The table in Additional file 3 describes in detail the methods used for each measurement in SURfit. It is an extension of the (Additional file 2: Table S1) in the paper. (DOCX 81 kb)
Additional file 1 of HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway
Creators: name: Guo, Kai
name: Ma, Zhiqiang
name: Zhang, Yujiao
name: Han, Lu
name: Shao, Changjian
name: Feng, Yingtong
name: Gao, Fei
name: Di, Shouyin
name: Zhang, Zhipei
name: Zhang, Jiao
name: Tabbò, Fabrizio
name: Ekman, Simon
name: Suda, Kenichi
name: Cappuzzo, Federico
name: Han, Jing
name: Li, Xiaofei
name: Yan, Xiaolong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 1: Figure 1. (a) The basal HDAC7 expressions of NSCLC cell lines. (b) Representative western blotting of cell cycle–related proteins in HDAC7 overexpression and knockdown cells. (c) Flow cytometry results of cell-cycle distribution at indicated time points. (d) Gross photograph of subcutaneous xenograft tumors, tumor growth curve and subcutaneous tumor weight in each group. (e) Representative western blot of EMT-associated proteins in HDAC7 overexpression and knockdown cells. Representative fluorescence images (f) and fluorescence signals analysis (g) of pulmonary metastases 4 weeks after tail vein injection. (h) Representative HE staining images of lung samples from indicated groups. Scale bar, 1 mm and 100 μm (inset), respectively. (i) The number of metastatic nodules per lung in HE staining images. (j) Representative general morphology of surface lung metastases. The black triangular arrows indicate the metastatic nodules. β-actin was used as internal control. All the data are expressed as mean ± SD. *P < 0.05. LV, lentivirus.
Local and global strong solutions for SQG in bounded domains
Creators: name: Constantin, Peter
name: Nguyen, Huy Quang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q35, 35Q86

description: We prove local well-posedness for the inviscid surface quasigeostrophic (SQG) equation in bounded domains of $\mathbb{R}^2$. When fractional Dirichlet Laplacian dissipation is added, global existence of strong solutions is obtained for small data for critical and supercritical cases. Global existence of strong solutions with arbitrary data is obtained in the subcritical cases.
Conversion of electronic to magnonic spin current at heavy-metal magnetic-insulator interface
Creators: name: Wang, Xi-guang
name: Li, Zhi-xiong
name: Zhou, Zhen-wei
name: Nie, Yao-zhuang
name: Xia, Qing-lin
name: Zeng, Zhong-ming
name: Chotorlishvili, L.
name: Berakdar, J.
name: Guo, Guang-hua
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Electronic spin current is convertible to magnonic spin current via the creation or annihilation of thermal magnons at the interface of a magnetic insulator and a metal with a strong spin-orbital coupling. So far this phenomenon was evidenced in the linear regime. Based on analytical and fulledged numerical results for the non-linear regime we demonstrate that the generated thermal magnons or magnonic spin current in the insulator is asymmetric with respect to the charge current direction in the metal and exhibits a nonlinear dependence on the charge current density, which is explained by the tuning effect of the spin Hall torque and the magnetization damping. The results are also discussed in light of and are in line with recent experiments pointing to a new way of non-linear manipulation of spin with electrical means.
description: to appear in Phys. Rev. B., Rapid Comm
Novel small molecule modulators of quorum sensing in avian pathogenic Escherichia coli (APEC)
Creators: name: Helmy, Yosra A.
name: Deblais, Loic
name: I. Kassem, Issmat
name: Kathayat, Dipak
name: Rajashekara, Gireesh
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Colibacillosis caused by avian pathogenic E. coli (APEC), is an economically important bacterial disease of poultry. APEC are a subgroup of extra intestinal pathogenic E. coli (ExPEC) and poultry are considered potential sources of foodborne ExPEC to humans. Currently, APEC infections in poultry are controlled by antibiotics and/or vaccination; however, their effect is limited due to emergence of antibiotic resistant strains and infections with heterologous serotypes. Therefore, novel approaches are needed. Here, using the bioluminescent quorum sensing (QS) autoinducer 2 (AI-2) indicator Vibrio harveyi BB170, we screened the cell free culture supernatant of APEC O78 prepared from cultures grown in the presence of 4,182 small molecules (SMs; 100 μM). A total of 69 SMs inhibited > 75% of APEC O78 AI-2 activity in the indicator bacteria. Ten SMs that showed highest AI-2 inhibition were selected for further studies. Most of these SMs inhibited the AI-2 activity of other APEC serotypes and significantly reduced APEC O78 biofilm formation and motility. Most compounds showed minimal toxicity on human intestinal cells (Caco-2), chicken macrophage (HD-11), and chicken and sheep red blood cells, and reduced APEC survival in HD-11 and THP-1 macrophages. The SMs induced no or minimal toxicity and conferred protection against APEC in wax moth larval model. SMs affected the expression of APEC O78 QS, virulence, biofilm and motility associated genes providing insight on their potential mode(s) of action. Further testing in chickens will facilitate development of these SMs as novel therapeutics to control APEC in poultry and thereby also reduce zoonotic transmission.
Additional file 4: of Insulin-like growth factor receptor and sphingosine kinase are prognostic and therapeutic targets in breast cancer
Creators: name: Ochnik, Aleksandra
name: Baxter, Robert
Publisher: name: figshare
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Survival outcomes in relation to p-IGF1R protein expression in HER2 and PR-positive and negative breast cancer tissues. Kaplan-Meier analysis was performed to measure the overall survival (OS) following stratification for high vs. low p-IGF1R protein expression, stratified for HER2 and PR expression: A. p-IGF1R (HER2-negative); B. p-IGF1R (HER2-positive); C. p-IGF1R (PR-negative) and D. p-IGF1R (PR-negative) as described under Methods. (DOCX 279Â kb)
Density-Dependent Quantum Hall States and Zeeman Splitting in Monolayer and Bilayer WSe$_2$
Creators: name: Movva, Hema C. P.
name: Fallahazad, Babak
name: Kim, Kyounghwan
name: Larentis, Stefano
name: Taniguchi, Takashi
name: Watanabe, Kenji
name: Banerjee, Sanjay K.
name: Tutuc, Emanuel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We report a study of the quantum Hall states (QHSs) sequence of holes in mono- and bilayer WSe$_2$. The QHSs sequence transitions between predominantly even and predominantly odd filling factors as the hole density is tuned in the range $1.6 - 12\times10^{12}$ cm$^{-2}$. The QHSs sequence is insensitive to the transverse electric field, and tilted magnetic field measurements reveal an insensitivity of the QHSs sequence to the in-plane magnetic field, evincing that the hole spin is locked perpendicular to the WSe$_2$ plane. These observations imply that the QHSs sequence is controlled by the Zeeman-to-cyclotron energy ratio, which remains constant as a function of perpendicular magnetic field at a fixed carrier density, but changes as a function of density due to strong electron-electron interaction.
description: 5 pages, 4 figures
An ecoimmunological approach to study evolutionary and ancient links between coagulation, complement and Innate immunity
Creators: name: Papareddy, Praveen
name: Kasetty, Gopinath
name: Alyafei, Saud
name: Smeds, Emanuel
name: Salo-Ahen, Outi M. H.
name: Hansson, Stefan R.
name: Egesten, Arne
name: Herwald, Heiko
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Coagulation, complement, and innate immunity are tightly interwoven and form an alliance that can be traced back to early eukaryotic evolution. Here we employed an ecoimmunological approach using Tissue Factor Pathway Inhibitor (TFPI)-1-derived peptides from the different classes of vertebrates (i.e. fish, reptile, bird, and mammals) and tested whether they can boost killing of various human bacterial pathogens in plasma. We found signs of species-specific conservation and diversification during evolution in these peptides that significantly impact their antibacterial activity. Though all peptides tested executed bactericidal activity in mammalian plasma (with the exception of rodents), no killing was observed in plasma from birds, reptiles, and fish, pointing to a crucial role for the classical pathway of the complement system. We also observed an interference of these peptides with the human intrinsic pathway of coagulation though, unlike complement activation, this mechanism appears not to be evolutionary conserved.
Complex acoustic environments: concepts, methods and auditory perception
Creators: name: Weisser, Adam
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: In everyday life, the ears constantly receive information from the environment that is carried by sound waves. Despite the uncontrolled nature of this information, normal hearing listeners can make sense of the unstructured sounds. In contrast, hearing has mostly been studied using acoustic stimuli that are rigidly controlled. The difference between understanding such artiﬁcial stimuli and real-world hearing has produced the distinction of ’complex acoustic environments‘ (CAEs) – a catch-all term for everything that the laboratory-based stimuli are not. However, an exact deﬁnition has been elusive, despite growing use in hearing research – especially in research focusing on hearing-impaired individuals, who struggle communicating in cocktail-party like scenarios. In this work, several aspects of CAEs were studied with the intention to understand where the complexity lies. The work consists of four main parts in manuscript form. The ﬁrst paper presents the Ambisonic Recordings of Typical Environments (ARTE) database, which contains 3D recordings of everyday scenarios. These were the primary stimuli used in all subsequent parts of this work. In the second paper, the speech and noise levels of real conversations were measured at two distances between talkers. The third paper reviews the origins and uses of the CAE concept in literature and presents a framework that summarizes and deﬁnes the characteristics that can drive complexity in a given environment. A subset of these characteristics were tested by 65 listeners who listened to the ARTE scenes (also with target speech), while answering a three-stage questionnaire. The analysis revealed that listeners’ perceived complexity is associated with both the loudness and the variability of the scenes. The ﬁnal paper analyzes the responses of listeners to an open-ended auditory scene analysis task using ARTE, and the observed limitations are discussed. A concluding discussion dissects how the auditory system deals with realistic amounts of acoustic information.
Additional file 2 of HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway
Creators: name: Guo, Kai
name: Ma, Zhiqiang
name: Zhang, Yujiao
name: Han, Lu
name: Shao, Changjian
name: Feng, Yingtong
name: Gao, Fei
name: Di, Shouyin
name: Zhang, Zhipei
name: Zhang, Jiao
name: Tabbò, Fabrizio
name: Ekman, Simon
name: Suda, Kenichi
name: Cappuzzo, Federico
name: Han, Jing
name: Li, Xiaofei
name: Yan, Xiaolong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 2: Figure 2. (a) Heatmap of RNA-seq data from SK-LU-1 cells overexpressing HDAC7 or the control based on the log2 intensity. (b) The GO function enrichment analysis of DEGs in SK-LU-1 cells overexpressing HDAC7 or the control, ranked by the P value. (c) The quantification changes of FGF18 in the culture medium after up- or downregulating HDAC7 in NSCLC cells. (d) Gross photograph of subcutaneous xenograft tumors, tumor growth curve and tumor weight in indicated groups. Representative fluorescence images (e) and fluorescence signals analysis (f) of pulmonary metastases 4 weeks after tail vein injection. (g) Representative HE staining images of lung samples from indicated groups. Scale bar, 1 mm and 100 μm (inset), respectively. (h) The number of metastatic nodules per lung in HE staining images. (i) Representative general morphology of surface lung metastases. The black triangular arrows indicate the metastatic nodules. All the data are expressed as mean ± SD. *P < 0.05. LV, lentivirus.
Optical Depth Estimates and Effective Critical Densities of Dense Gas Tracers in the Inner Parts of Nearby Galaxy Discs
Creators: name: Jimenez-Donaire, M. J.
name: Bigiel, F.
name: Leroy, A. K.
name: Cormier, D.
name: Gallagher, M.
name: Usero, A.
name: Bolatto, A.
name: Colombo, D.
name: Garcia-Burillo, S.
name: Hughes, A.
name: Kramer, C.
name: Krumholz, M. R.
name: Meier, D. S.
name: Murphy, E.
name: Pety, J.
name: Rosolowsky, E.
name: Schinnerer, E.
name: Schruba, A.
name: Tomicic, N.
name: Zschaechner, L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: High critical density molecular lines like HCN(1-0) or HCO+(1-0) represent our best tool to study currently star-forming, dense molecular gas at extragalactic distances. The optical depth of these lines is a key ingredient to estimate the effective density required to excite emission. However, constraints on this quantity are even scarcer in the literature than measurements of the high density tracers themselves. Here, we combine new observations of HCN, HCO+ and HNC(1-0) and their optically thin isotopologues H13CN, H13CO+ and HN13C(1-0) to measure isotopologue line ratios. We use IRAM 30-m observations from the large program EMPIRE and new ALMA observations, which together target 6 nearby star-forming galaxies. Using spectral stacking techniques, we calculate or place strong upper limits on the HCN/H13CN, HCO+/H13CO+ and HNC/HN13C line ratios in the inner parts of these galaxies. Under simple assumptions, we use these to estimate the optical depths of HCN(1-0) and HCO+(1-0) to be τ~2-11 in the active, inner regions of our targets. The critical densities are consequently lowered to values between 5-20$\times 10^5$, 1-3$\times 10^5$ and 9$\times 10^4$ cm-3 for HCN, HCO+ and HNC, respectively. We study the impact of having different beam-filling factors, $η$, on these estimates and find that the effective critical densities decrease by a factor of $\frac{η_{12}}{η_{13}}\,τ_{12}$. A comparison to existing work in NGC 5194 and NGC 253 shows HCN/H13CN and HCO+/H13CO+ ratios in agreement with our measurements within the uncertainties. The same is true for studies in other environments such as the Galactic Centre or nuclear regions of AGN-dominated nearby galaxies.
description: Accepted for publication in Monthly Notices of the Royal Astronomical Society
Spectrally-resolved UV photodesorption of CH4 in pure and layered ices
Creators: name: Dupuy, Rémi
name: Bertin, Mathieu
name: Féraud, Géraldine
name: Michaut, Xavier
name: Jeseck, Pascal
name: Doronin, Mikhail
name: Philippe, Laurent
name: Romanzin, Claire
name: Fillion, Jean-Hugues
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Context. Methane is among the main components of the ice mantles of insterstellar dust grains, where it is at the start of a rich solid-phase chemical network. Quantification of the photon-induced desorption yield of these frozen molecules and understanding of the underlying processes is necessary to accurately model the observations and the chemical evolution of various regions of the interstellar medium. Aims. This study aims at experimentally determining absolute photodesorption yields for the CH4 molecule as a function of photon energy. The influence of the ice composition is also investigated. By studying the methane desorption from layered CH4:CO ice, indirect desorption processes triggered by the excitation of the CO molecules is monitored and quantified. Methods. Tunable monochromatic VUV light from the DESIRS beamline of the SOLEIL synchrotron is used in the 7 - 13.6 eV (177 - 91 nm) range to irradiate pure CH4 or layers of CH4 deposited on top of CO ice samples. The release of species in the gas phase is monitored by quadrupole mass spectrometry and absolute photodesorption yields of intact CH4 are deduced. Results. CH4 photodesorbs for photon energies higher than ~9.1 eV (~136 nm). The photodesorption spectrum follows the absorption spectrum of CH4, which confirms a desorption mechanism mediated by electronic transitions in the ice. When it is deposited on top of CO, CH4 desorbs between 8 and 9 eV with a pattern characteristic of CO absorption, indicating desorption induced by energy transfer from CO molecules. Conclusions. The photodesorption of CH4 from the pure ice in various interstellar environments is around 2.0 x 10^-3 molecules per incident photon. Results on CO-induced indirect desorption of CH4 provide useful insights for the generalization of this process to other molecules co-existing with CO in ice mantles.
ROTEIRO DE SIMULAÇÃO IN SITU SOBRE CUIDADOS IMEDIATOS E MEDIATOS AO RECÉM-NASCIDO (RN) A TERMO
Creators: name: Pereira, Bárbara Silvestre da Silva
name: Da Silva, Laura Johanson
Publisher: name: Zenodo
Year: 2024

description: Roteiro de Simulação IN SITU, para Graduandos de Enfermagem do 6º período, objetivando o desenvolvimento de habilidades e competências nos alunos em realizar os cuidados imediatos e mediatos ao recém-nascido a termo, assegurando itervenções específicas, seguras e humanizadas, além de incentivar a comunicação eficaz com mãe e acompanhante.
An ecoimmunological approach to study evolutionary and ancient links between coagulation, complement and Innate immunity
Creators: name: Papareddy, Praveen
name: Kasetty, Gopinath
name: Alyafei, Saud
name: Smeds, Emanuel
name: M. H. Salo-Ahen, Outi
name: R. Hansson, Stefan
name: Egesten, Arne
name: Herwald, Heiko
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Coagulation, complement, and innate immunity are tightly interwoven and form an alliance that can be traced back to early eukaryotic evolution. Here we employed an ecoimmunological approach using Tissue Factor Pathway Inhibitor (TFPI)-1-derived peptides from the different classes of vertebrates (i.e. fish, reptile, bird, and mammals) and tested whether they can boost killing of various human bacterial pathogens in plasma. We found signs of species-specific conservation and diversification during evolution in these peptides that significantly impact their antibacterial activity. Though all peptides tested executed bactericidal activity in mammalian plasma (with the exception of rodents), no killing was observed in plasma from birds, reptiles, and fish, pointing to a crucial role for the classical pathway of the complement system. We also observed an interference of these peptides with the human intrinsic pathway of coagulation though, unlike complement activation, this mechanism appears not to be evolutionary conserved.
Additional file 3: of Customer satisfaction of Vietnam Airline domestic service quality
Creators: name: Khanh, Giao Ha Nam
Publisher: name: figshare
Year: 2017
Subjects: subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Difference test. (DOCX 21Â kb)
Thermal convection with mixed thermal boundary conditions: Effects of insulating lids at the top
Creators: name: Wang, Fei
name: Huang, Shi-Di
name: Xia, Ke-Qing
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The effects of insulating lids on the convection beneath were investigated experimentally using rectangular convection cells in the flux Rayleigh number range $2.3\times10^{9}\leq Ra_F \leq 1.8\times10^{11}$ and cylindrical cells in the range $1.4\times10^{10}\leq Ra_F \leq 1.2\times10^{12}$ with the Prandtl number Pr fixed at 4.3. It is found that the presence of the insulating lids leads to reduction of the global heat transfer efficiency as expected, which primarily depends on the insulating area but is insensitive to the detailed insulating patterns. At the leading order level, the magnitude of temperature fluctuation in the bulk fluid is, again, found to be insensitive to the insulating pattern and mainly depends on the insulating area; while the temperature probability density function (PDF) in the bulk is essentially invariant with respect to both insulating area and the spatial pattern of the lids. The flow dynamics, on the other hand, is sensitive to both the covering area and the spatial distribution of the lids. At fixed $Ra_F$, the flow strength is found to increase with increasing insulating area so as to transfer the same amount of heat through a smaller cooling area. Moreover, for a constant insulating area, a symmetric insulating pattern results in a symmetric flow pattern, i.e. double-roll structure; whereas asymmetric insulating pattern leads to asymmetric flow, i.e. single-roll structure. It is further found that the symmetry breaking of the insulating pattern leads to a stronger flow that enhances the horizontal velocity more than the vertical one.
description: Submited to JFM
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00032
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00032, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00032, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
In-utero Diagnosis of Prostatic Embryonal Rhabdomyosarcoma
Creators: name: Schiller, Emily
name: Joshi, Parth
name: El-Ali, Alexander
name: Brenseke, William
name: Magid, Margret S.
name: Wexler, Leonard
name: Gitlin, Jordan
Publisher: name: PRIME
Year: 2024
Subjects: classificationCode: 3213
subject: Paediatrics
classificationCode: 321302
subject: Infant and child health
classificationCode: 320222
subject: Radiology and organ imaging
classificationCode: 320214
subject: Nephrology and urology
classificationCode: 320220
subject: Pathology (excl. oral pathology)

description: AbstractThough rhabdomyosarcoma is the most common soft-tissue tumor diagnosed in children there are no reported cases of prenatally detected prostatic embryonal rhabdomyosarcoma. This report demonstrates the first reported case of this phenomenon and its subsequent workup, diagnosis, and treatment.
Eicosanoid biosynthesis influences the virulence of Candida parapsilosis
Creators: name: Chakraborty, Tanmoy
name: Thuer, Ernst
name: Heijink, Marieke
name: Tóth, Renáta
name: Bodai, László
name: Vágvölgyi, Csaba
name: Giera, Martin
name: Gabaldón, Toni
name: Gácser, Attila
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Lipid mediators, derived from arachidonic acid metabolism, play an important role in immune regulation. The functions of bioactive eicosanoids range from modulating cytokine signaling and inflammasome formation to anti-inflammatory and pro-resolving activities. Human pathogenic fungi such as Candida albicans, Candida parapsilosis, Cryptococcus neoformans and Aspergillus fumigatus have been shown to produce such lipid mediators, associated with their virulence. To date, investigations into the molecular mechanisms of fungal eicosanoid biosynthesis in different species have revealed that several genes are associated with prostaglandin production. However, these routes remain uncharacterized in C. parapsilosis with early results suggesting it uses pathways distinct from those found in C. albicans. Therefore, we aimed to identify and characterize C. parapsilosis genes involved in eicosanoid biosynthesis. Following arachidonic acid treatment of C. parapsilosis cells, we identified several genes interfering with prostaglandin production. Out of the identified genes, homologues of a multi copper oxidase (FET3), an Acyl-CoA thiolase (POT1) and an Acyl-CoA oxidase (POX1-3) were found to play a significant role in prostaglandin synthesis. Furthermore, all three genes were confirmed to enhance C. parapsilosis pathogenicity, as the corresponding deletion mutants were cleared more efficiently by human macrophages and induced higher levels of pro-inflammatory cytokines. In addition, the mutants were less virulent than the wild-type strain in a mouse model of systemic infection. Taken together, we identified three genes that regulate eicosanoid biosynthesis in C. parapsilosis and impact the fungus’ virulence.
Nested Dissection Solver for Transport in 3D Nano-Electronic Devices
Creators: name: Zhao, Y.
name: Hetmaniuk, U.
name: Patil, S. R.
name: Qi, J.
name: Anantram, M. P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The Hierarchical Schur Complement method (HSC), and the HSC-extension, have significantly accelerated the evaluation of the retarded Green's function, particularly the lesser Green's function, for two-dimensional nanoscale devices. In this work, the HSC-extension is applied to determine the solution of non-equilibrium Green's functions (NEGF) on three-dimensional nanoscale devices. The operation count for the HSC-extension is analyzed for a cuboid device. When a cubic device is discretized with $N \times N \times N$ grid points, the state-of-the-art Recursive Green Function (RGF) algorithm takes $\mathcal{O}(N^7)$ operations, whereas the HSC-extension only requires $\mathcal{O}(N^6)$ operations. %Realistic operation counts also depend on the system dimensions in $xyz$-directions and the form of contact self-energy matrix. Operation counts and runtimes are also studied for three-dimensional nanoscale devices of practical interest: a graphene-boron\- nitride-graphene multilayer system, a silicon nanowire, and a DNA molecule. The numerical experiments indicate that the cost for the HSC-extension is proportional to the solution of one linear system (or one LU-factorization) and that the runtime speed-ups over RGF exceed three orders of magnitude when simulating realistic devices, such as a graphene-boron nitride-graphene multilayer system with 40,000 atoms.
GOCI Yonsei Aerosol Retrieval (YAER) algorithm and validation during the DRAGON-NE Asia 2012 campaign
Creators: name: Choi, Myungje
name: Kim, Jhoon
name: Lee, Jaehwa
name: Kim, Mijin
name: Park, Young-Je
name: Jeong, Ukkyo
name: Kim, Woogyung
name: Hong, Hyunkee
name: Holben, Brent
name: Eck, Thomas
name: Song, Chul H.
name: Lim, Jae-Hyun
name: Song, Chang-Keun
Publisher: name: EGU
Year: 2016

description: The Geostationary Ocean Color Imager (GOCI) onboard the Communication, Ocean, and Meteorological Satellite (COMS) is the first multi-channel ocean color imager in geostationary orbit. Hourly GOCI top-of-atmosphere radiance has been available for the retrieval of aerosol optical properties over East Asia since March 2011. This study presents improvements made to the GOCI Yonsei Aerosol Retrieval (YAER) algorithm together with validation results during the Distributed Regional Aerosol Gridded Observation Networks – Northeast Asia 2012 campaign (DRAGON-NE Asia 2012 campaign). The evaluation during the spring season over East Asia is important because of high aerosol concentrations and diverse types of Asian dust and haze. Optical properties of aerosol are retrieved from the GOCI YAER algorithm including aerosol optical depth (AOD) at 550 nm, fine-mode fraction (FMF) at 550 nm, single-scattering albedo (SSA) at 440 nm, Ångström exponent (AE) between 440 and 860 nm, and aerosol type. The aerosol models are created based on a global analysis of the Aerosol Robotic Networks (AERONET) inversion data, and covers a broad range of size distribution and absorptivity, including nonspherical dust properties. The Cox–Munk ocean bidirectional reflectance distribution function (BRDF) model is used over ocean, and an improved minimum reflectance technique is used over land. Because turbid water is persistent over the Yellow Sea, the land algorithm is used for such cases. The aerosol products are evaluated against AERONET observations and MODIS Collection 6 aerosol products retrieved from Dark Target (DT) and Deep Blue (DB) algorithms during the DRAGON-NE Asia 2012 campaign conducted from March to May 2012. Comparison of AOD from GOCI and AERONET resulted in a Pearson correlation coefficient of 0.881 and a linear regression equation with GOCI AOD  =  1.083  ×  AERONET AOD − 0.042. The correlation between GOCI and MODIS AODs is higher over ocean than land. GOCI AOD shows better agreement with MODIS DB than MODIS DT. The other GOCI YAER products (AE, FMF, and SSA) show lower correlation with AERONET than AOD, but still show some skills for qualitative use.
Additional file 2: Table S1. of A partially supervised physical activity program for adult and adolescent survivors of childhood cancer (SURfit): study design of a randomized controlled trial [NCT02730767]
Creators: name: Rueegg, Corina
name: Kriemler, Susi
name: Zuercher, Simeon
name: Schindera, Christina
name: Renner, Andrea
name: Hebestreit, Helge
name: Meier, Christian
name: Eser, Prisca
name: Weid, Nicolas Von Der
Publisher: name: figshare
Year: 2017
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Schedule of enrolment, interventions and assessments within SURfit (DOCX 138 kb)
Formulaic expressions in official Roman Republican epistolography inscribed in Greek
Creators: name: Haddad, Christopher Joseph
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Official Roman Republican letters inscribed in Greek have been neglected in recent scholarship on Ancient Greek and Roman epistolography, and the language of these letters in particular has not yet received satisfactory treatment. The letters have been assessed against texts which differ from them temporally, geographically, and in terms of media and text type. This has resulted in criticism of their language and their authors’ capabilities. These letters are important for understanding Greek and Roman history, epistolography, languages, and bilingualism, and their language is in need of a reassessment which applies relevant comparanda and is sensitive to the Koine Greek of documentary evidence. One important feature of the language of the Roman letters inscribed in Greek is the formulaic expressions. Since they require a knowledge of the language as well as familiarity with the text type, they are revealing of the authors’ understanding of official epistolography in Koine Greek. This dissertation analyses the form and function of formulaic language in these Roman letters in Greek. It demonstrates the attention which the authors paid to formulaic language and the proficiency with which they applied the Greek language in their official letters.
The role of oral vocabulary in the development of children’s orthographic representations
Creators: name: Wegener, Signy
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: When children learn to read, how do they come to be able to recognise whole written words quickly and accurately? Knowledge of letter-to-sound correspondences and the sound structure of language are known to be important early in reading acquisition but other cognitive factors must also contribute to the development of skilled reading. One such factor is oral vocabulary (knowledge of the pronunciation and meaning of words), yet its association with reading acquisition remains poorly understood. This thesis aims to elucidate the nature of the relationship between oral vocabulary and reading, with a particular focus on how they might interact as children acquire representations of new written words. According to the orthographic skeleton hypothesis (Chapter 2), children can draw on their knowledge of phoneme-to-grapheme correspondences to generate expectations of the spellings of known spoken words prior to viewing them in writing for the first time. In a series of training studies, Grade 4 children are taught novel oral vocabulary prior to reading these trained items and matched untrained items in sentence contexts while their eye movements are monitored. In each experiment the orthographic skeleton hypothesis is interrogated with a view to providing an elaborated account of their generation and influence on written word learning. Results shed light on the roles of lexical phonology and semantics within the development of orthographic expectancies (Chapter3); the form of the skeleton (Chapter 4); and the influence of the skeleton on subsequent visual exposures to target words (Chapter 5). Findings are linked back to established theories of reading acquisition, the role of oral vocabulary within this process and the causal mechanisms that support this influence (Chapter 6).
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 117
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: Petot, Frédéric
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 117, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 117, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Electromagnetic scaling functions within the Green's Function Monte Carlo approach
Creators: name: Rocco, N.
name: Alvarez-Ruso, L.
name: Lovato, A.
name: Nieves, J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We have studied the scaling properties of the electromagnetic response functions of $^4$He and $^{12}$C nuclei computed by the Green's Function Monte Carlo approach, retaining only the one-body current contribution. Longitudinal and transverse scaling functions have been obtained in the relativistic and non relativistic cases and compared to experiment for various kinematics. The characteristic asymmetric shape of the scaling function exhibited by data emerges in the calculations in spite of the non relativistic nature of the model. The results are consistent with scaling of zeroth, first and second kinds. Our analysis reveals a direct correspondence between the scaling and the nucleon-density response functions.
description: 11 pages, 15 figures
Exploring the circular polarisation of low-frequency solar radio bursts with LOFAR
Creators: name: Morosan, Diana E.
name: Räsänen, Juska E.
name: Kumari, Anshu
name: Kilpua, Emilia K. J.
name: Bisi, Mario M.
name: Dabrowski, Bartosz
name: Krankowski, Andrzej
name: Magdalenić, Jasmina
name: Mann, Gottfried
name: Rothkaehl, Hanna
name: Vocks, Christian
name: Zucca, Pietro
Publisher: name: arXiv
Year: 2022
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The Sun is an active star that often produces numerous bursts of electromagnetic radiation at radio wavelengths. Low frequency radio bursts have recently been brought back to light with the advancement of novel radio interferometers. However, their polarisation properties have not yet been explored in detail, especially with the Low Frequency Array (LOFAR), due to difficulties in calibrating the data and accounting for instrumental leakage. Here, using a unique method to correct the polarisation observations, we explore the circular polarisation of different sub-types of solar type III radio bursts and a type I noise storm observed with LOFAR, which occurred during March-April 2019. We analysed six individual radio bursts from two different dates. We present the first Stokes V low frequency images of the Sun with LOFAR in tied-array mode observations. We find that the degree of circular polarisation for each of the selected bursts increases with frequency for fundamental emission, while this trend is either not clear or absent for harmonic emission. The type III bursts studied, that are part of a long--lasting type III storm, can have different senses of circular polarisation, occur at different locations and have different propagation directions. This indicates that the type III bursts forming a classical type III storm do not necessarily have a common origin but instead they indicate the existence of multiple, possibly unrelated, acceleration processes originating from solar minimum active regions.
description: 19 pages, 6 figures
A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus
Creators: name: Moscoso, Miriam
name: García, Patricia
name: Cabral, Maria P.
name: Rumbo, Carlos
name: Bou, Germán
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Staphylococcus aureus infections are becoming a major global health issue due to the rapid emergence of multidrug-resistant strains. Therefore, there is an urgent need to develop an effective vaccine to prevent and control these infections. In order to develop a universal immunization strategy, we constructed a mutant derivative of S. aureus 132 which lacks the genes involved in D-alanine biosynthesis, a structural component of cell wall peptidoglycan. This unmarked deletion mutant requires the exogenous addition of D-alanine for in vitro growth. The aim of this study was to examine the ability of this D-alanine auxotroph to induce protective immunity against staphylococcal infection. Our findings demonstrate that this deletion mutant is highly attenuated, elicits a protective immune response in mice and generates cross-reactive antibodies. Moreover, the D-alanine auxotroph was completely eliminated from the blood of mice after its intravenous or intraperitoneal injection. We determined that the protective effect was dependent on antibody production since the adoptive transfer of immune serum into naïve mice resulted in effective protection against S. aureus bacteremia. In addition, splenocytes from mice immunized with the D-alanine auxotroph vaccine showed specific production of IL-17A after ex vivo stimulation. We conclude that this D-alanine auxotroph protects mice efficiently against virulent staphylococcal strains through the combined action of antibodies and IL-17A, and therefore constitutes a promising vaccine candidate against staphylococcal disease, for which no licensed vaccine is available yet.
Frequency-Multiplexed bias and readout of a 16-pixel Superconducting Nanowire Single-Photon Detector Array
Creators: name: Doerner, Steffen
name: Kuzmin, Artem
name: Wuensch, Stefan
name: Charaev, Ilya
name: Boes, Florian
name: Zwick, Thomas
name: Siegel, Michael
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We demonstrate a 16-pixel array of radio-frequency superconducting nanowire single-photon detectors with an integrated and scalable frequency-division multiplexing architecture, reducing the required bias and readout lines to a single microwave feed line. The electrical behavior of the photon-sensitive nanowires, embedded in a resonant circuit, as well as the optical performance and timing jitter of the single detectors is discussed. Besides the single pixel measurements we also demonstrate the operation of the 16-pixel array with a temporal, spatial and photon-number resolution.
Additional file 3 of HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway
Creators: name: Guo, Kai
name: Ma, Zhiqiang
name: Zhang, Yujiao
name: Han, Lu
name: Shao, Changjian
name: Feng, Yingtong
name: Gao, Fei
name: Di, Shouyin
name: Zhang, Zhipei
name: Zhang, Jiao
name: Tabbò, Fabrizio
name: Ekman, Simon
name: Suda, Kenichi
name: Cappuzzo, Federico
name: Han, Jing
name: Li, Xiaofei
name: Yan, Xiaolong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 3: Figure 3. (a) The relative TOP/FOP ratio in HDAC7 overexpression or knockdown NSCLC cells. The mRNA (b) and protein levels (c) of β-catenin related genes in HDAC7 overexpression or knockdown NSCLC cells. (d) Representative western blotting of HDAC7-β-catenin-FGF18 pathway involved proteins in indicated NSCLC cells. (e) Mass spectrometry analysis results of USP10 peptide sequence (IAELLENVTLIHKPVSLQP). (f) Representative HDAC7 and USP10 IHC images of NSCLC and adjacent non-tumor tissues. Scale bar, 200 μm and 50 μm (inset), respectively. Correlation analysis of HDAC7 and USP10 expression in NSCLC tissues (g) and in adjacent non-tumor tissues (h). β-actin was used as internal control. All the data are expressed as mean ± SD. *P < 0.05. LV, lentivirus.