cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells
Creators: name: Hoffelner, Beate Sandra
name: Andreev, Stanislav
name: Plank, Nicole
name: Koch, Pierre
Publisher: name: Universität Regensburg
Year: 2023
Subjects: subject: kinase inhibitor; pyridinyl imidazole; covalent inhibitor; photoactivation; caging group; JNK3
subject: 615 Pharmazie

description: The concept of photocaging represents a promising approach to acquire spatiotemporal control over molecular bioactivity. To apply this strategy to pyridinylimidazole-based covalent JNK3 inhibitors, we used acrylamido-N-(4-((4-(4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl)pyridin-2-yl)amino)phenyl)benzamide (1) as a lead compound to design novel covalent inhibitors of JNK3 by modifying the amide bond moiety in the linker. The newly synthesized inhibitors demonstrated IC50 values in the low double-digit nanomolar range in a radiometric kinase assay. They were further characterized in a NanoBRETTM intracellular JNK3 assay, where covalent engagement of the target enzyme was confirmed by compound washout experiments and a loss in binding affinity for a newly generated JNK3(C154A)-NLuc mutant. The most potent compound of the series, N-(3-acrylamidophenyl)-4-((4-(4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl)pyridin-2-yl)amino)benzamide (13), was equipped with a photolabile protecting group leading to a nearly 10-fold decrease in intracellular JNK3 binding affinity, which was fully recovered by UV irradiation at a wavelength of 365 nm within 8 min. Our results highlight that photocaged covalent inhibitors can serve as a pharmacological tool to control JNK3 activity in live cells with light.
title: o-bib. Das offene Bibliotheksjournal / Herausgeber VDB, Bd. 2 Nr. 1 (2015)
title: o-bib. Das offene Bibliotheksjournal, Ausgabe 1/2015
titleType: AlternativeTitle
Creators: name: O-Bib. Das Offene Bibliotheksjournal / Herausgeber VDB
Publisher: name: o-bib. Das offene Bibliotheksjournal / Herausgeber VDB
Year: 2015

description: Landes- und Regionalverbände...92-106 Kommissionen...77-91 Vorstand und Vereinsausschuss...75-76 Terminvorschau...107-110 Hollmann, Michael; Schüller-Zwierlein, André (Hg.): Diachrone Zugänglichkeit als Prozess. Kulturelle Überlieferung in systematischer Sicht. Berlin/München/Boston: de Gruyter Saur, 2014 (Age of Access? Grundfragen der Informationsgesellschaft, Bd. 4)....56-63 Griebel, Rolf; Schäffler, Hildegard; Söllner, Konstanze (Hg.): Praxishandbuch Bibliotheksmanagement. 2 Bände. Berlin/München/Boston: de Gruyter Saur, 2015....47-55 Geokoordinaten in Bibliotheksdaten. Grundlage für innovative Nachnutzung...35-46 Forschung für die Praxis – Perspektiven für Bibliotheks- und Informationsmanagement...68-74 Datenschutzrecht und bibliothekarische Praxis...64-67 Quo vadis Inhaltserschließung der Deutschen Nationalbibliothek? Herausforderungen und Perspektiven...15-26 Die Arbeitsgruppe der deutschen Handschriftenzentren - Servicezentren für Handschriftenerschließung und -digitalisierung...1-14 Management von Article Processing Charges - Herausforderungen für Bibliotheken...27-34
Quantum transport of strongly interacting photons in a one-dimensional nonlinear waveguide
Creators: name: Hafezi, Mohammad
name: Chang, Darrick
name: Gritsev, Vladimir
name: Demler, Eugene
name: Lukin, Mikhail
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a theoretical technique for solving the quantum transport problem of a few photons through a one-dimensional, strongly nonlinear waveguide. We specifically consider the situation where the evolution of the optical field is governed by the quantum nonlinear Schrödinger equation (NLSE). Although this kind of nonlinearity is quite general, we focus on a realistic implementation involving cold atoms loaded in a hollow-core optical fiber, where the atomic system provides a tunable nonlinearity that can be large even at a single-photon level. In particular, we show that when the interaction between photons is effectively repulsive, the transmission of multi-photon components of the field is suppressed. This leads to anti-bunching of the transmitted light and indicates that the system acts as a single-photon switch. On the other hand, in the case of attractive interaction, the system can exhibit either anti-bunching or bunching, which is in stark contrast to semiclassical calculations. We show that the bunching behavior is related to the resonant excitation of bound states of photons inside the system.
description: 22 pages, 24 figures
title: Evaluation of Responsible Beverage Service to Reduce Impaired Driving by 21- to 34-Year-Old Drivers [Traffic Tech]
Creators: name: National Highway Traffic Safety Administration
Publisher: name: National Highway Traffic Safety Administration
publisherIdentifier: https://ror.org/04gcfqs37
publisherIdentifierScheme: ROR
Year: 2017
Subjects: classificationCode: https://trt.trb.org/term/91561
subject: Adults
classificationCode: https://trt.trb.org/term/90842
subject: Alcohol use
classificationCode: https://trt.trb.org/term/90852
subject: Drinking establishments
classificationCode: https://trt.trb.org/term/91759
subject: Drunk drivers
classificationCode: https://trt.trb.org/term/90848
subject: Drunk driving
classificationCode: https://trt.trb.org/term/91758
subject: Impaired drivers
classificationCode: https://trt.trb.org/term/90900
subject: Law enforcement
classificationCode: https://trt.trb.org/term/92481
subject: Restaurants
classificationCode: https://trt.trb.org/term/90919
subject: Traffic arrests

description: Young adult drivers 21 to 34 years old are a particularly highrisk group for impaired-driving-related crashes. Numerous studies have found that approximately half of intoxicated drivers had their last drink at a licensed bar or restaurant, and the most significant risk factors associated with drinking and driving were the amount of alcohol consumed and whether obviously intoxicated customers continued to be served. In a systematic review of interventions designed to reduce alcohol use and its related harms in drinking environments, results of the studies indicated that responsible beverage service (RBS) training and follow-up enforcement and/or monitoring could be effective tools in lowering the rates of high-risk alcohol consumption and impaired driving. Some of the results suggest that RBS training can be effective as one aspect of a multi-component intervention. The objective of this study was to implement and evaluate a multi-faceted intervention that integrated outreach and responsible beverage service training, targeted enforcement, and corrective actions by an enforcement agency to a random sample of identified problem bars. The goal of the RBS/enforcement program—through training and enforcement—was to reduce the practices of over-serving and serving obviously intoxicated individuals in bars and restaurants. The long-term goal of the program was to reduce driving-while-intoxicated (DWI) arrests and impaired-driving-related traffic crashes involving 21- to 34-year-olds.
Bifurcation of Plasma Balls and Black Holes to Lobed Configurations
Creators: name: Cardoso, Vitor
name: Dias, Oscar J. C.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: At high energy densities any quantum field theory is expected to have an effective hydrodynamic description. When combined with the gravity/gauge duality an unified picture emerges, where gravity itself can have a formal holographic hydrodynamic description. This provides a powerful tool to study black holes in a hydrodynamic setup. We study the stability of plasma balls, holographic duals of Scherck-Schwarz (SS) AdS black holes. We find that rotating plasma balls are unstable against m-lobed perturbations for rotation rates higher than a critical value. This unstable mode signals a bifurcation to a new branch of non-axisymmetric stationary solutions which resemble a "peanut-like" rotating plasma. The gravitational dual of the rotating plasma ball must then be unstable and possibly decay to a non-axisymmetric long-lived SS AdS black hole. This instability provides therefore a mechanism that bounds the rotation of SS black holes. Our results are strictly valid for the SS AdS gravity theory dual to a SS gauge theory. The latter is particularly important because it shares common features with QCD, namely it is non-conformal, non-supersymmetric and has a confinement/deconfinement phase transition. We focus our analysis in 3-dimensional plasmas dual to SS AdS_5 black holes, but many of our results should extend to higher dimensions and to other gauge theory/gravity dualities with confined/deconfined phases and admitting a fluid description.
description: 32 pages, 7 figures
Unfolding first-principles band structures
Creators: name: Ku, Wei
name: Berlijn, Tom
name: Lee, Chi-Cheng
Publisher: name: arXiv
Year: 2010
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A general method is presented to unfold band structures of first-principles super-cell calculations with proper spectral weight, allowing easier visualization of the electronic structure and the degree of broken translational symmetry. The resulting unfolded band structures contain additional rich information from the Kohn-Sham orbitals, and absorb the structure factor that makes them ideal for a direct comparison with angular resolved photoemission spectroscopy experiments. With negligible computational expense via the use of Wannier functions, this simple method has great practical value in the studies of a wide range of materials containing impurities, vacancies, lattice distortions, or spontaneous long-range orders.
description: 4 pages, 3 figures
Dinner with Osiris, Or How to Make Your Own Osiris Vegetans
Creators: name: Rocheleau, Caroline M.
Publisher: name: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums
Year: 2021

description: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums, No. 5 (2021): Offerings to Maat. Essays in Honour of Emily Teeter
Coevolutionary Genetic Algorithms for Establishing Nash Equilibrium in Symmetric Cournot Games
Creators: name: Protopapas, Mattheos K.
name: Kosmatopoulos, Elias B.
name: Battaglia, Francesco
Publisher: name: arXiv
Year: 2009
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We use co-evolutionary genetic algorithms to model the players' learning process in several Cournot models, and evaluate them in terms of their convergence to the Nash Equilibrium. The "social-learning" versions of the two co-evolutionary algorithms we introduce, establish Nash Equilibrium in those models, in contrast to the "individual learning" versions which, as we see here, do not imply the convergence of the players' strategies to the Nash outcome. When players use "canonical co-evolutionary genetic algorithms" as learning algorithms, the process of the game is an ergodic Markov Chain, and therefore we analyze simulation results using both the relevant methodology and more general statistical tests, to find that in the "social" case, states leading to NE play are highly frequent at the stationary distribution of the chain, in contrast to the "individual learning" case, when NE is not reached at all in our simulations; to find that the expected Hamming distance of the states at the limiting distribution from the "NE state" is significantly smaller in the "social" than in the "individual learning case"; to estimate the expected time that the "social" algorithms need to get to the "NE state" and verify their robustness and finally to show that a large fraction of the games played are indeed at the Nash Equilibrium.
description: 18 pages, 4 figures
Riskeeriv liikluskäitumine ning riskikäitumise markerid kooliõpilastel ja sõidukijuhtidel. Doktoriväitekirja kokkuvõte
Creators: name: Eensoo, Diva
Publisher: name: OÜ Celsius Healthcare
Year: 2008
Subjects: riskeeriv liikluskäitumine, isiksuseomadused, aju serotoniinisüsteemi markerid, vereliistakute monoamiinide oksüdaasi aktiivsus, serotoniinitransportija geeni promootoripiirkonna polümorﬁ sm

description: Töö eesmärgiks on uurida kooliõpilaste ja sõidukijuhtide riskeerivat käitumist liikluses ning seda mõjutavaid tegureid, mis annaks võimaluse teadmisi rakendades paremini suunata ennetavat tegevust liiklusvigastuste alal. Riski  käitumist liikluses mõjutavad kombinatsioonis mitmesugused isiksuslikud, käitumuslikud ning bioloogilised tegurid. Töös on näidatud riskeeriva liiklus  käitumise seoseid riski  käitumise markeritega aju serotoniini (5-HT) süsteemis nagu vereliistakute monoamiinide oksüdaasi (v-MAO) aktiivsuse ja serotoniinitransportija geeni promootoripiirkonna (5-HTTLPR) polümorﬁ smiga.


Eesti Arst 2008; 87(4):255−259
description: Eesti Arst, Aprill 2008
Kehaline aeroobne võimekus ja selle mõjutamine korduva depressiivse häirega perearstipatsientidel
Creators: name: Maaroos, Heidi-Ingrid
name: Tähepõld, Heli
name: Maaroos, Jaak
name: Suija, Kadri
name: Kalda, Ruth
name: Pechter, Ülle
Publisher: name: OÜ Celsius Healthcare
Year: 2008

description: Uuringu eesmärgiks oli hinnata depressiooniga patsientide kehalist võimekust ja kehalise aktiivsuse taseme testimise metoodika sobivust ning uurida regulaarse iseseisva kepikõnni mõju depressiooniga patsientide meeleolule ja aeroobsele kehalisele võimekusele. Uuringusse kaasatud korduva depressiivse häirega patsiendid hindasid oma eelnevat kehalist aktiivsust väheseks, valmisolek ja motiveeritus liikumisravi alustamiseks oli kolmandikul küsitletuist. Aeroobse kehalise võimekuse hindamiseks kasutati 2 km kõndimise testi. Liikumis  ravist osavõtjad tegelesid 12 nädala jooksul iseseisvalt vähemalt kolm korda nädalas kepikõnniga. Kehalise aeroobse võimekuse indeks depressiooniga patsientidel uuringu alguses oli väike, regulaarne kepikõnd parandas kehalist võimekust, mille tase jäi siiski keskmisest tunduvalt madalamaks. Patsientide hinnangul nende meeleolu regulaarse kehalise aktiivsuse tulemusena paranes.

Eesti Arst 2008; 87(4):250−254
description: Eesti Arst, Aprill 2008
Ümarvari kopsus
Creators: name: Laisaar, Tanel
Publisher: name: OÜ Celsius Healthcare
Year: 2008
Subjects: ümarvari kopsus, kopsuvähk, kopsutuumor

description: Ümarvari kopsus on võrdlemisi sage kliiniline probleem, mille korral on põhiküsimuseks täpse morfoloogilise diagnoosi kinnitamine. Ümarkolle võib olla primaarne kopsuvähk, üksik kopsumetastaas, healoomuline kasvaja, tuber  kuloom või muu. Diagnoosimine koosneb üksikasjalikust anamneesist, erinevate võimalike haiguste tõenäosuse hindamisest, mitmetest radioloogilistest uuringutest ja sageli ka invasiivsetest diagnostikameetoditest. Diagnoosi kinnitamiseks võib vajalikuks osutuda videotorakoskoopiline kopsuresektsioon, mis healoomuliste kollete puhul on ühtlasi ka lõplikuks ravimeetodiks. Pahaloomuliste haiguskollete puhul võimaldab torakoskoopial saadud täpne diagnoos planeerida edasist ravitaktikat.

Eesti Arst 2008; 87(4):260−268
description: Eesti Arst, Aprill 2008
Kas antidepressandid on toimetud ravimid?
Creators: name: Sinisalu, Väino
Publisher: name: OÜ Celsius Healthcare
Year: 2008

description: „Eestis müüakse kümnete miljonite eest kasutuid antidepressante“ väideti Postimehe 2008. a 28. veebruari artiklis. Autor toetus 2008. a veebruarikuus avaldatud artiklile ajakirjas PLOS Medicine, kus Suurbritannia Hulli ülikooli teadlased jõudsid antidepressantide toimest avaldatud artiklite metaanalüüsil järeldusele, et antidepressantide toime depressiooni ravis ei erine oluliselt platseebo toimest, seda isegi raske depressiooni korral. See uudis on tekitanud nõutust nii arstide kui ka patsientide hulgas. On siis tõepoolest antidepressandid kasutud ravimid, nagu väidab ajaleht?

Eesti Arst 2008; 87(4)288−291
description: Eesti Arst, Aprill 2008
Morgan Library Statue of Tjanefer Son of Nespamedu (CK 971)
Creators: name: Rashed, Mohamed Gamal
Publisher: name: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums
Year: 2021

description: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums, No. 5 (2021): Offerings to Maat. Essays in Honour of Emily Teeter
KOREYS BADIIY ADABIYOTIDA RIVOJLANISH BOSQICHLARI VA JANR XUSUSIYATLARI
Creators: name: Amonova, Dilafruz
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqolada koreys adabiyotining shakllanish bosqichlari bilan bir qatorda davrlar osha yaratilgan asarlarning janr xususiyatlari, mazmuni haqida yoritib o’tilgan. Xususan, koreys adiblarining millat, til va madaniyat ruhida yaratilgan asrlar va ularning janrlari haqida fikr bildirilgan. Hamda koreys yozuvi paydo bo’lish davrlarni ham o’z ichiga olgan.
Aktiivsus-tähelepanuhäire lastel
Creators: name: Liivamägi, Jüri
Publisher: name: OÜ Celsius Healthcare
Year: 2008
Subjects: püsimatus, tähelepanuhäire, hüperaktiivne laps, aktiivsus-tähelepanuhäire

description: Eri maades ja eri aegadel tehtud epidemioloogilised uuringud näitavad aktiivsus-tähelepanuhäire (ATH) ebaühtlast levimust. Ilmneb häire oluline sagenemistendents: 1989. a hinnati Inglismaal ATH levimuseks 0,05%, USAs 1,5% üldrahvastikust; viimastel aastatel paljudes maades tehtud uuringute tulemusel on täheldatud selle häire levimuseks üldrahvastikus enamasti 37%, mõnedes uuringutes isegi 10–20% (1). Nähtavasti sõltuvad uuringute tulemused uuritavate ealisest ja soolisest jaotuvusest (poistel esineb ATHd 2–9 korda sagedamini kui tüdrukutel), kultuuri- ja kasvatustraditsioonidest (reglementeeritum või vabam kasvatus), sotsiaalse ümbruse (esmajoones õpetajate, vanemate) “taluvusest” laste käitumise suhtes jm. Suur osatähtsus on ka uuringutel kasutatud diagnostilistel skaaladel ja häire eristamiskriteeriumidel. RHK-10 esitab ATH diagnoosimisel rangemad nõuded ja selle järgi on ATH levimuse riikidevahelised erinevused väiksemad (2).

Eesti Arst 2008; 87(4):280−287
description: Eesti Arst, Aprill 2008
Additional file 1 of Maternal effects drive intestinal development beginning in the embryonic period on the basis of maternal immune and microbial transfer in chickens
Creators: name: Gong, Haizhou
name: Wang, Taiping
name: Wu, Min
name: Chu, Qianran
name: Lan, Hainan
name: Lang, Wuying
name: Zhu, Lingyu
name: Song, Yang
name: Zhou, Yujie
name: Wen, Qiongyi
name: Yu, Jing
name: Wang, Baolin
name: Zheng, Xin
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1: Table S1. Basal diet composition of experimental laying breeder hens and chicks. Table S2. Chick-brooding management. Table S3. Primers for qPCR. Table S4. Quality control of RNAs for sequencing. Table S5. Concentrations of purified PCR amplicons. Table S6. RNA-seq quality control of read filtration. Table S7. Mapping summary. Table S8. The 107 shared taxa among magnum, egg white, and E15 and E21 embryonic gut. Figure S1. Experimental design. Figure S2. Electrophoresis results of PCR amplification products with positive and negative controls. Marker = 2000, 1000, 750, 500, 250 and 100 bp from top to bottom (TaKaRa, DL2000 DNA Marker). Figure S3. Gene coverage of each sample for mapping quality control. CON and CCAB are abbreviated as A and C in the figure. Figure S4. (a). Growth performance of the offspring chicks from 1 to 21 d of age. Data are shown as the means + SEMs. Student’s t test was conducted. ns P ≥ 0.05, *P < 0.05 and **P < 0.01. n = 30 chicks. (b) Embryo mortality in the CON (left) and CCAB (right) groups. Embryo mortality = dead embryo number/fertile egg number. Set egg number = 900 eggs in each group. The number of fertile eggs was 792 and 797 in the CON and CCAB groups, respectively. Figure S5. IgA, IgG, IgM, LYZ and AvBDs levels in embryonic serum (a) and egg white (b); the levels of IgA, IgG and IgM in embryonic yolk sac fluid (c); and the levels of LYZ and AvBDs in amniotic fluid (d) as determined by ELISA. Data are means ± SEMs. Student’s t test was conducted. ns P ≥ 0.05 and *P < 0.05. Figure S6. Microbial composition at the phylum (a) and genus (b) levels in the magnum (abbreviated as mag), egg white (abbreviated as EW), and E15 and E21 embryonic gut in each sample. Figure S7. Significantly enriched taxa (log10(LDA score) > 2, P < 0.05) in the magnum (a; abbreviated as mag), egg white (b; abbreviated as EW), and embryonic gut at E15 (c) and E21 (d) between groups as determined by LEfSe with Kruskal‒Wallis and Wilcoxon tests and the one against-all strategy.
Ensemble of ultra-high intensity attosecond pulses from laser-plasma interaction
Creators: name: Bulanov, S. S.
name: Maksimchuk, A.
name: Krushelnick, K.
name: Popov, K. I.
name: Bychenkov, V. Yu.
name: Rozmus, W.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The efficient generation of intense X-rays and $γ$-radiation is studied. The scheme is based on the relativistic mirror concept, {\it i.e.}, a flying thin plasma slab interacts with a counterpropagating laser pulse, reflecting part of it in the form of an intense ultra-short electromagnetic pulse having an up-shifted frequency. In the proposed scheme a series of relativistic mirrors is generated in the interaction of the intense laser with a thin foil target as the pulse tears off and accelerates thin electron layers. A counterpropagating pulse is reflected by these flying layers in the form of an ensemble of ultra-short pulses resulting in a significant energy gain of the reflected radiation due to the momentum transfer from flying layers.
description: 6 pages, 2 figures. Phys. Lett. A, in press
The chevalier de lat Tour Landry : an assessment of his "livre" with particular reverence to the education of women
Creators: name: Rumpf, Marcelle Irene
Publisher: name: University of British Columbia
Year: 2011

description: I. Purpose To place the Livre and its author in their historical setting, in order to evaluate their contribution to ideas on the education of women. II. Development 1. An outline of cultural influences in Mediaeval France. 2. A description of texts on the education of girls and women prior to the time of the Chevalier de La Tour Landry, noting changes in ideas. Contributions made by Vincent de Beauvais and Pierre Dubois. The influence of the Dicta Catonis, a little book of maxims. 3. The position and condition of women of noble families as a result of certain cultural influences such as that of Courtly Love. 4. An analysis of the examples contained in the Livre, giving an overall picture of the virtues which one could expect to find in an honourable woman with a Christian upbringing. III. Conclusion The Livre and its author in relation to the influences of their time and place. A defense against later critics. Definition of "enseignement,” and evaluation of the Livre and its author in the light of the meaning of this term.
title: FMCSA Safety Program Effectiveness Measurement: Roadside Intervention Effectiveness Model Fiscal Year 2013: Analysis Brief
title: FMCSA Safety Program Effectiveness Measurement: Roadside Intervention Effectiveness Model FY 2013: Analysis Brief.
titleType: AlternativeTitle
Creators: name: Horton, Suzanne
name: Segev, Eran
name: Meltzer, Neil
name: Federal Motor Carrier Safety Administration
Publisher: name: Federal Motor Carrier Safety Administration
publisherIdentifier: https://ror.org/01jt5mq34
publisherIdentifierScheme: ROR
Year: 2017
Subjects: classificationCode: https://trt.trb.org/term/93227
subject: Commercial vehicles
classificationCode: https://trt.trb.org/term/91993
subject: Motor carriers
classificationCode: https://trt.trb.org/term/90631
subject: Safety programs
classificationCode: https://trt.trb.org/term/89726
subject: Performance measurement
classificationCode: https://trt.trb.org/term/90414
subject: Inspection
classificationCode: https://trt.trb.org/term/90900
subject: Law enforcement
classificationCode: https://trt.trb.org/term/90662
subject: Traffic crashes

description: The Roadside Inspection and Traffic Enforcement programs are two of FMCSA’s most powerful safety tools. By continually examining the results of these programs, FMCSA can ensure that they are being executed effectively and are producing the desired safety benefits. Results for individual States can be examined and compared to provide guidance on how to allocate safety resources. The total national results show the scale of the Roadside Inspection and Traffic Enforcement programs and the magnitude of their effects on highway safety. In 2013, these programs saved an estimated 448 lives and prevented 8,450 injuries by averting 13,919 crashes. Since 2001, these programs are estimated to have saved more than 7,500 lives.
On the QALE geometry of Nakajima's metric
Creators: name: Carron, Gilles
Publisher: name: arXiv
Year: 2008
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C25, 53C26, 32S20

description: We show that on Hilbert scheme of $n$ points on $\C^2$, the hyperkähler metric construsted by H. Nakajima via hyperkähler reduction is the Quasi-Asymptotically Locally Euclidean (QALE in short) metric constructed by D. Joyce.
Pika ahelaga rasvhapete oksüdatsiooni defekt imikul. Haigusjuhu kirjeldus
Creators: name: Joost, Kairit
name: Kilk, Kalle
name: Toome, Liis
name: Žordania, Riina
name: Soomets, Ursel
Publisher: name: OÜ Celsius Healthcare
Year: 2008
Subjects: rasvhapete oksüdatsioon, LCHAD puudulikkus, HELLP-sündroom, hüpoglükeemia

description: Pika ahelaga rasvhapete oksüdatsiooni defekt (LCHAD puudulikkus) on mittespetsiiﬁ  lise kliinilise pildiga pärilik ainevahetushaigus, mis võib põhjustada letaalset metaboolset dekompensatsiooni. Kirjanduse alusel on haigusesse suremus ligi 40%. Varajase diagnostika korral on haiguse kulgu võimalik efektiivselt mõjutada spetsiiﬁ  lise vähese rasva- ja suure süsivesikusisaldusega dieetraviga. Haiguse kindlakstegemine presümptomaatilises perioodis on võimalik atsüülkarnitiinide tandemmassspektromeetrilisel analüüsil. Artiklis käsitletakse letaalse lõppega hüpoglükeemiat imikul, kus LCHAD puudulikkus diagnoositi post mortem molekulaargeneetiliselt ning vastsündinute testkaardil säilitatud vere atsüülkarnitiinide analüüsil esines LCHAD puudulikkusele iseloomulik atsüülkarnitiinide proﬁil.

Eesti Arst 2008; 87(4):274−279
description: Eesti Arst, Aprill 2008
Time-dependent current density functional theory via time-dependent deformation functional theory: A constrained search formulation in the time domain
Creators: name: Tokatly, I. V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The logical structure and the basic theorems of time-dependent current density functional theory (TDCDFT) are analyzed and reconsidered from the point of view of recently proposed time-dependent deformation functional theory (TDDefFT). It is shown that the formalism of TDDefFT allows to avoid a traditional external potential-to-density/current mapping. Instead the theory is formulated in a form similar to the constrained search procedure in the ground state DFT. Within this formulation of TDCDFT all basic functionals appear from the solution of a constrained universal many-body problem in a comoving reference frame, which is equivalent to finding a conditional extremum of a certain universal action functional. As a result the physical origin of the universal functionals entering the theory, as well as their proper causal structure becomes obvious. In particular, this leaves no room for any doubt concerning predictive power of the theory.
description: revtex4, 24 pages
Quantized Chebyshev polynomials and cluster characters with coefficients
Creators: name: Dupont, G.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Representation Theory (math.RT)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: 13F60, 16G99

description: We introduce quantized Chebyshev polynomials as deformations of generalized Chebyshev polynomials previously introduced by the author in the context of acyclic coefficient-free cluster algebras. We prove that these quantized polynomials arise in cluster algebras with principal coefficients associated to acyclic quivers of infinite representation types and equioriented Dynkin quivers of type $\mathbb A$. We also study their interactions with bases and especially canonically positive bases in affine cluster algebras.
description: 28 pages. Final version, to appear in Journal of Algebraic Combinatorics
The International Politics of Progressive Legislations: Pakistan’s Transgender Persons Protection of Rights Act (2018)
Creators: name: Panhwar, Bakhtawar
Publisher: name: University of Chicago
Year: 2023
Subjects: subject: Khwaja Sira
subject: Pakistan
subject: political struggle
subject: progressive legislations
subject: Reputation Points
subject: Signalling
subject: Transgender Rights

description: This research examines the phenomenon of progressive legislations passed in otherwise conservative countries. The explanations focus on how the domestic and international avenues of political engagement and activism need to inter-lap for such legislations to pass. International instances of signaling, deflection and reputation are interlinked with domestic factors such as protests, public contention and local political elite to create the conditions necessary for passing such legislations. The socio-political cleavages in this research focus on the Khwaja Sira (Transgender) community in the Islamic Republic of Pakistan. In 2018, Pakistan's Supreme Court issued a decision that would go down in history as a watershed event for the transgender population and the country as a whole. This was seen as the monumental step towards progress for Pakistan's transgender population and claimed by the International Commission of Jurists as globally one of the most progressive laws on transgender community. Pakistan's transgender minority has endured prejudice and isolation since the country's inception. Trans identifying individuals in Pakistan face severe stigmatization and otherness, and have been forced to live on the periphery of society as a result. Over time, both the government and society have seen these individuals and groups as outsiders, deviants, or a threat to the basis upon which society is constructed. The goal of this research is to question why despite the heavy social cost, a progressive bill was passed by the Pakistani government. Drawing on domestic and international explanations, this research identifies the politics (local and global) behind progressive legislations in non-consolidated, conservative countries. I aim to explore the socio-political and cultural knots using a mixed methods analysis. Quantitatively, the correlation between UN Sexual Orientation and Gender Identity (SOGI) voting records and the LGBTQ+ Global Index conceptualizes the international influence on a state’s strategic policies. The work also utilizes qualitative analysis of online content by queer activists, annotation of the passed bill itself and work done by the senators. By choosing the specific case of Pakistan, I also address some common misconceptions about the trans community and hope to encourage conversations around queerness in Pakistan. The findings inspect why the trans bill of 2018 was passed and annotates the effectiveness of the state's international strategic goals
ZAMONAVIY PSIXOLOGIYADA INNOVATSION METODLARDAN FOYDALANISH
Creators: name: ADCHTI Ijtimoiy-gumanitar fanlar, pedagogika va psixologiya kafedrasi o'qituvchisi Dumarova.G.K, Abduraxmonova Xulkaroy Xorijiy til va adabiyoti  104-guruh talabasi
Publisher: name: Zenodo
Year: 2023

description: Ushbu maqolada psixologiya fanining tadqiqot metodlari, ulardan foydalanish va eng qadimgi hamda zamonaviy metodlar oʻrtasidagi tafovutlar haqida soʻz yuritamiz. Shu bilan birga, jamoada sogʻlom psixologik muhit yaratish yoʻllari haqida fikr-mulohazalar bildiriladi.

Abstract: In this article, we will talk about experimental and modern methods in psychology, their usage, and the differences between the oldest and modern methods. At the same time, feedback is provided on ways to create a healthy psychological environment in the team.

Kalit so’zlar: Psixologok metodlar, kuzatish metodi, eksperimental psixologiya, psixodiagnostik tahlil, qiyoslash metodi, psixologik trening.

Key words: Psychological methods, tracking method, experimental psychology, psychodiagnostic analysis, comparison method, psychological training.
Sparse Channel Separation using Random Probes
Creators: name: Romberg, Justin
name: Neelamani, Ramesh
Publisher: name: arXiv
Year: 2010
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 94A12; 60H25; 15B05; 93E12

description: This paper considers the problem of estimating the channel response (or Green's function) between multiple source-receiver pairs. Typically, the channel responses are estimated one-at-a-time: a single source sends out a known probe signal, the receiver measures the probe signal convolved with the channel response, and the responses are recovered using deconvolution. In this paper, we show that if the channel responses are sparse and the probe signals are random, then we can significantly reduce the total amount of time required to probe the channels by activating all of the sources simultaneously. With all sources activated simultaneously, the receiver measures a superposition of all the channel responses convolved with the respective probe signals. Separating this cumulative response into individual channel responses can be posed as a linear inverse problem. We show that channel response separation is possible (and stable) even when the probing signals are relatively short in spite of the corresponding linear system of equations becoming severely underdetermined. We derive a theoretical lower bound on the length of the source signals that guarantees that this separation is possible with high probability. The bound is derived by putting the problem in the context of finding a sparse solution to an underdetermined system of equations, and then using mathematical tools from the theory of compressive sensing. Finally, we discuss some practical applications of these results, which include forward modeling for seismic imaging, channel equalization in multiple-input multiple-output communication, and increasing the field-of-view in an imaging system by using coded apertures.
Pelagio Palagi and the Belzoni Family Collection of Egyptian Antiquities
Creators: name: Picchi, Daniela
name: Chilò, Luca
Publisher: name: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums
Year: 2021

description: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums, No. 5 (2021): Offerings to Maat. Essays in Honour of Emily Teeter
Papyrus Fragment with an Embalming Scene from the Pushkin Museum of Fine Arts
Creators: name: Lavrentyeva, Nika V.
Publisher: name: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums
Year: 2021

description: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums, No. 5 (2021): Offerings to Maat. Essays in Honour of Emily Teeter
title: Estimating Motor Carrier Management Information System Crash File Underreporting From Carrier Records: Research Brief
title: Research Brief : Estimating Motor Carrier Management Information System Crash File Underreporting From Carrier Records
titleType: AlternativeTitle
Creators: name: University of Michigan–Ann Arbor: Transportation Research Institute: Transportation Research Institute
Publisher: name: Federal Motor Carrier Safety Administration: Office of Analysis, Research, and Technology
publisherIdentifier: https://ror.org/01jt5mq34
publisherIdentifierScheme: ROR
Year: 2017
Subjects: classificationCode: https://trt.trb.org/term/91996
subject: Truck lines
classificationCode: https://trt.trb.org/term/91993
subject: Motor carriers
classificationCode: https://trt.trb.org/term/90674
subject: Truck crashes
classificationCode: https://trt.trb.org/term/90662
subject: Traffic crashes
classificationCode: https://trt.trb.org/term/90729
subject: Crash reports
classificationCode: https://trt.trb.org/term/90728
subject: Crash records

description: This study estimated a significant amount of underreporting to the MCMIS crash file by the States, for the carriers who cooperated in the study. For the study carriers, it appears that the MCMIS file contained about 66 percent of their reportable crashes. Several sources of underreporting were identified. Arranging them in the chronological order of the crash reporting process (from crash event to State crash file to the MCMIS crash file), highlights the vulnerabilities in the reporting process. 1. About 56 percent of the missing crashes apparently had no police report filed. They were in the carriers’ crash data but were not found in State crash data. If no crash report is filed, the case cannot appear in the MCMIS crash file. 2. Among the missing crashes that were reported to State crash files, several factors contributed to their either not being uploaded to or not being found in the MCMIS crash file: a) Of the “study carrier” crashes that couldn’t be found in MCMIS by UMTRI, but could be found in State files, over half were cases that had either missing or incorrect DOT numbers. For the cases that had missing DOT numbers, UMTRI concluded that the officers filling out the Police Accident Reports believed that the crash was not reportable. For the cases that had incorrect DOT numbers, they were uploaded to MCMIS, but UMTRI couldn’t identify them due to the incorrect numbers. b) About 24 percent of the records missed were medium- and heavy-duty trucks that were misclassified as light vehicles. c) MCMIS-reportable crashes involving only trucks with in-State plates were less likely to be reported by States to MCMIS. d) In about half of the MCMIS-reportable cases in State files that were not reported, the crash severity, as coded, met the MCMIS severity threshold and the vehicles met the MCMIS vehicle criteria. This points to problems within States for identifying crashes in their data meeting the MCMIS reporting criteria.
Some aspects of the development of Philonema (Nematoda: Dracunculoidea) in Cyclops bicuspidatus Claus
Creators: name: Ko, Ronald Chun Chung
Publisher: name: University of British Columbia
Year: 2011

description: Development of Philonema oncorhynchi and Philonema agubernaculum in Cyclops bicuspidatus were followed and compared by experimentally infecting the copepods with larvae obtained from gravid female worms in spawning salmon and trout. Larvae were dissected from copepods for examination at an interval of two to three days. They were found to undergo two moults in the copepods. Three larval stages are described. All the larval stages of the two species of Philonema are morphologically identical. The rates of development of the larvae were observed to be directly proportional to temperatures between 4° to 15°C. The Q₁₀ for the range was calculated as 4. The rates of development at 10° were the same in the two species. The effects of temperature on larval development are discussed. An attempt is made to correlate the rates of development of Philonema larvae in the copepods under laboratory conditions and the infection of sockeye salmon in Cultus Lake, British Columbia.
Tuleohutusõpe haiglates
Creators: name: Tammepuu, Orm
Publisher: name: OÜ Celsius Healthcare
Year: 2008
Subjects: tulekahju tervishoiuasutuses, tuleennetus, tuleohutusõpe, tulekahjuõppus

description: Jämedalt üldistades võib öelda, et pärast taasiseseisvumist Eestis tuleennetus1 mõneks ajaks peaaegu seiskus. Tule  ohutus taandus teisejärguliseks, mööda vaadati ehituslikest tuleohutusnormidest, amortiseerusid tulekaitsepaigaldised2 ja unustusse vajusid regulaarsed tulekahjuõppused. Viimastel aastatel on jälle tuleennetusega tõsisemalt tegelema hakatud, ka Päästeamet tõstis 2006. a ennetustöö oma prioriteediks. Käesolev artikkel arutleb korraldusliku tulekaitse ühe võtmeküsimuse – tuleohutusõppe – üle, tuginedes viimaste aastate kogemusele Ida-Tallinna Keskhaiglas, Lääne-Tallinna Keskhaiglas ja Põhja-Eesti Regionaalhaiglas.

Eesti Arst 2008; 87(4):310−315
description: Eesti Arst, Aprill 2008
Optical Flares from the Tidal Disruption of Stars by Massive Black Holes
Creators: name: Strubbe, Linda E.
name: Quataert, Eliot
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: A star that wanders too close to a massive black hole (BH) is shredded by the BH's tidal gravity. Stellar gas falls back to the BH, releasing a flare of energy. In anticipation of upcoming transient surveys, we predict the light curves and spectra of tidal flares as a function of time, highlighting the unique signatures of tidal flares in the optical and near-IR. Some of the gas initially bound to the BH is likely blown away when the fallback rate is super-Eddington at early times. This outflow produces an optical luminosity comparable to that of a supernova; such events have durations of ~10 days and may have been missed in supernova searches that exclude the nuclear regions of galaxies. When the fallback rate subsides below Eddington, the gas accretes onto the BH via a thin disk whose emission peaks in the UV to soft X-rays. Some of this emission is reprocessed by the unbound stellar debris, producing a spectrum of very broad emission lines (with no corresponding narrow forbidden lines). These lines are strongest for BHs with MBH ~ 10^5 - 10^6 Msun and thus optical surveys are particularly sensitive to the lowest mass BHs in galactic nuclei. Calibrating our models to ROSAT and GALEX observations, we predict detection rates for Pan-STARRS, PTF, and LSST and highlight observational challenges in the optical. Pan-STARRS should detect at least several events per year--many more if current theoretical models of super-Eddington outflows are correct. These surveys will significantly improve our knowledge of stellar dynamics in galactic nuclei, the physics of super-Eddington accretion, the demography of intermediate mass BHs, and the role of tidal disruption in the growth of massive BHs.
description: Accepted for publication in MNRAS
COMPASSIONATE CARE CHALLENGES AND BARRIERS IN UNDERGRADUATE NURSING STUDENTS
Creators: name: Khadija Al Shukaili
name: Javed Iqbal
name: Amir Sultan
name: Afsha Bibi
name: Ashfaq Ahmad
name: Marayam Ali Khalaf Al Tamimi
name: Dr. Maliha B. Thapur
name: Fazal Khaliq
name: Dr. Gautum Laximkant Sharma, MD
name: Dr. Mahvesh Qureshi
name: Adnan Yousef
name: Nasir Ali
name: Nafeesa Zafar
Publisher: name: Zenodo
Year: 2023
Subjects: Compassionate Care, Challenges, Barriers, Undergraduate Nursing Students.

description: Abstract

Background: A fundamental aspect of nursing care excellence is compassion. It is regarded as one of the cornerstones of patient-centered care. Objective: To explore the compassionate care challenges and barriers in undergraduate nursing students. Methodology: This study employed a cross-sectional analytical design to explore nursing students' challenges in providing compassionate care. The research utilized a convenient sampling method and collected data through an online Google Form survey. A total of 101 nursing students were part of this study. Result: Key challenges include workload inconsistencies (58.4% yes), organizational neglect of nurse needs (79.2% yes), lack of compassionate role models (52.5% yes), focus on routines over patients (58.4% yes), gender bias in compassionate behaviour (64.4% yes), absence of holistic care (60.4% yes), nurses' attitudes (79.2% yes), implausible friendliness in medical relations (70.3% yes), and language barriers (65.3% yes). Conclusion: The findings reveal significant challenges in compassionate care among undergraduate nursing students, notably in workload management, organizational support, role modelling, gender biases, and communication barriers. Addressing these issues is crucial to enhancing nursing education and fostering a more compassionate healthcare environment, emphasizing the need for targeted interventions and supportive policies in nursing curricula.
title: National Transportation Library [Brochure]
Creators: name: Bureau of Transportation Statistics
Publisher: name: Bureau of Transportation Statistics
publisherIdentifier: https://ror.org/05xfdey77
publisherIdentifierScheme: ROR
Year: 2016
Subjects: classificationCode: https://trt.trb.org/term/92539
subject: Libraries
classificationCode: https://trt.trb.org/term/97309
subject: Library operations
classificationCode: https://trt.trb.org/term/97294
subject: Guides to information
classificationCode: https://trt.trb.org/term/92125
subject: Federal government agencies
classificationCode: https://trt.trb.org/term/92130
subject: Transportation departments

description: Description of the National Transportation Library and its services, in 2016.
Theban Tomb 118: its Foreign ‘Tribute’ Scene and its Owner Amenmose
Creators: name: Hunt Gordon, Andrew
Publisher: name: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums
Year: 2021

description: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums, No. 5 (2021): Offerings to Maat. Essays in Honour of Emily Teeter
New Finds of the Twenty-fifth Dynasty Period from El-Kurru, Sudan
Creators: name: Emberling, Geoff
name: Elamim, Sami
Publisher: name: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums
Year: 2021

description: CIPEG Journal: Ancient Egyptian & Sudanese Collections and Museums, No. 5 (2021): Offerings to Maat. Essays in Honour of Emily Teeter
Tervishoiutöötaja kohustused piinamise ja ebainimliku kohtlemise tuvastamisel
Creators: name: Amos, Mari
Publisher: name: OÜ Celsius Healthcare
Year: 2008
Subjects: isikute väärkohtlemine, tervishoiutöötaja kohustused

description: Eesti ühines Ühinenud Rahvaste Organisatsiooni piinamise ning muu julma, ebainimliku või inimväärikust alandava kohtlemise ja karistamise vastase konventsiooniga 01.06.2002. Konventsiooni artikli 10 kohaselt peavad piinamise keelustamist käsitlevad õppematerjalid ja teave olema täies ulatuses lisatud programmidesse, mille põhjal valmistatakse ette muu hulgas ka meditsiinipersonali. Tervishoiutöötaja on kohustatud täitma teatud rahvusvahelisi nõudeid piinamise ja ebainimliku kohtlemise tuvastamisel.

Eesti Arst 2008; 87(4):306−309
description: Eesti Arst, Aprill 2008
The effect of inhomogenities on single molecule imaging by hard XFEL pulses
Creators: name: Jurek, Zoltan
name: Faigel, Gyula
Publisher: name: arXiv
Year: 2009
Subjects: subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We study the local distortion of the atomic structure in small biological samples illuminated by x-ray free electron laser (XFEL) pulses. We concentrate on the effect of inhomogenities: heavy atoms in a light matrix and non-homogeneous spatial distribution of atoms. In biological systems we find both. Using molecular-dynamics type modeling it is shown that the local distortions about heavy atoms are larger than the average distortion in the light matrix. Further it is also shown that the large spatial density fluctuations also significantly alter the time evolution of atomic displacements as compared to samples with uniform density. This fact has serious consequences on single particle imaging. This is discussed and the possibility of a correction is envisaged.
description: Movies: http://www.szfki.hu/~jurek/art2009_1/index.html