cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Data Literacy Snack: GDPR applicability – introduction to the interactive Virtual Assistant iVA
Creators: name: Stoilova, Vasilka
name: Oberländer, Lars
name: Herklotz, Markus
Publisher: name: Zenodo
Year: 2022

description: In this follow-up Data Literacy Snack we tackle the question “When is GDPR applicable?”. Along with some practical examples we introduce the interactive Virtual Assistant iVA: a tool, which helps researchers deal with data protection topics.
Analysis of cluster explosive synchronization in complex networks
Creators: name: Ji, Peng
name: Peron, Thomas K. DM.
name: Rodrigues, Francisco A.
name: Kurths, Jürgen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Correlations between intrinsic dynamics and local topology have become a new trend in the study of synchronization in complex networks. In this paper, we investigate in this paradigm the influence of topology on dynamics of networks made up of second-order Kuramoto oscillators. In particular, based on mean-field calculations, we provide a detailed investigation of the recently reported phenomena of cluster explosive synchronization (CES)[Phys. Rev. Lett. 110, 218701 (2013)], analysing the model in scale-free and small-world networks as a function of several topological properties. We show that, in contrast to scale-free networks, the transition to the synchronous state in small-world structures tends to be continuous as the probability of rewiring increases. These results complement the previous findings regarding CES and also fundamentally deepen the understanding of the interplay between topology and dynamics under the constraint of correlating natural frequencies and local structure.
description: Accepted in PRE
title: The Funding Buffet: Understanding the  sources of capital to finance your venture - Technical Note
Creators: name: Alemany, Luisa
name: Dushnitsky, Gary
Publisher: name: London Business School
Year: 2021
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: This technical note is an introduction to the world of financing entrepreneurial ventures. It is a primer on the different stages of a business and the different types of financing available. Most of the capital that high-growth entrepreneurial businesses will secure to fund their future plans is private capital. Private capital includes all the equity financing that is not in public equities; i.e. publicly listed companies. Hence, private capital includes not only venture capital and private equity, but also business angels and equity crowdfunding. We will go deeper into these sources in section 2 of this note.
description: LBS Case Code: TN-21-003
title: Natura & Co: Sustainability at Scale
Creators: name: Turconi, Stefano
name: Singh, Pranjal
name: Wang, Ruik
Publisher: name: London Business School
Year: 2021
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: Established in 1969 as a cosmetics lab in the city of Sao Paulo, Natura grew briskly over the ensuing decades and by 2004 it had become Brazil's largest beauty company. Unlike its competitors, Natura was built on the principle of reconciling socioecological sustainability with value creation. During the 2010s, Natura evolved from a strong regional player focused on a single brand and direct sales to a multinational, multi-brand, multi-channel group and renamed itself Natura &Co. Its three business units, Natura, Aesop and The Body Shop, operated independently, with decision-making autonomy and their own CEOs and executive teams. Each unit continued to grow and operate sustainably, but group profitability plummeted. In May 2019 Natura &Co announced that it had agreed to acquire mass-market beauty company Avon in a transaction worth $3.7 billion. The takeover would present several challenges, from turning around underperforming Avon to developing a coherent corporate strategy without betraying Natura's sustainability ethos.
description: LBS Case Code: CS-21-003
title: Satya Nadella at Microsoft: Instilling a Growth Mindset (Chinese)
Creators: name: Ibarra, Herminia
name: Rattan, Aneeta
Publisher: name: London Business School
Year: 2021
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: When Satya Nadella took over as CEO of Microsoft in 2014, he inherited a firm fading toward irrelevance, plagued by internal fights and inertia. Earlier that year his wife, Anu, had given him a best-selling book by Stanford psychologist Carol Dweck entitled Mindset: The New Psychology of Success, suspecting it might give Nadella some ideas for Microsoft. He adapted the idea to encourage employees to shift from Microsoft's historical 'know-it-alls' culture to embrace a 'learn-it-alls' curiosity. The case study provides background on Nadella's challenges and context, as well as how he and his leadership team executed their culture change effort.
description: LBS Case Code: CS-18-008_CN
title: Commercial International Bank: Leading Transformation in Turbulent Times Empowering People, Winning With Data
Creators: name: Peterson, Randall
Publisher: name: London Business School
Year: 2018
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: In 2011, Cairo became the cradle of the Egyptian revolution. Transport workers, ambulance drivers and bank employees called for the end of President Hosni Mubarak's regime. With a backdrop of volatility, Commercial International Bank (CIB), Egypt's leading private bank, embarked on a major transformation. Hisham Ezz-El Arab, Chairman of CIB, placed customers, employees and shareholders at the heart of everything: his decision to invest in turbulent times went against conventional wisdom. In 2015, he hired Islam Zekry as chief data officer (CDO) to lead a new decision-making support unit. Trust was central. In the Arab region, leaders have power but they must also consult. Data transformation became the main pillar of the bank's strategy, but Zekry's team faced obstacles. The data geek squad proposed changes ranging from product offerings to advances in blockchain. In July 2017, CIB was named the 'World's Best Bank in the Emerging Markets'  by Euromoney. Still, its challenges were unmatched. More Egyptians were unbanked than banked and the country was dealing with an ailing tourism sector and soaring inflation. The bank's future success would rely on the combination of data analytics, human capital, leadership and a culture of openness.
description: LBS Case Code: CS-18-004
Optimal Power Flow as a Polynomial Optimization Problem
Creators: name: Ghaddar, Bissan
name: Marecek, Jakub
name: Mevissen, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optimization and Control (math.OC)
subject: Systems and Control (eess.SY)
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Formulating the alternating current optimal power flow (ACOPF) as a polynomial optimization problem makes it possible to solve large instances in practice and to guarantee asymptotic convergence in theory.
description: A more concise version, which also fixes a number of minor issues
Microscopic description of fission in Uranium isotopes with the Gogny energy density functional
Creators: name: Rodriguez-Guzman, R.
name: Robledo, L. M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The most recent parametrizations D1S, D1N and D1M of the Gogny energy density functional are used to describe fission in the isotopes $^{232-280}$ U. Fission paths, collective masses and zero point quantum corrections, obtained within the constrained Hartree-Fock-Bogoliubov approximation, are used to compute the systematics of the spontaneous fission half-lives $t_\mathrm{SF}$, the masses and charges of the fission fragments as well as their intrinsic shapes. The Gogny-D1M parametrization has been benchmarked against available experimental data on inner and second barrier heights, excitation energies of the fission isomers and half-lives in a selected set of Pu, Cm, Cf, Fm, No, Rf, Sg, Hs and Fl nuclei. It is concluded that D1M represents a reasonable starting point to describe fission in heavy and superheavy nuclei. Special attention is also paid to understand the uncertainties in the predicted $t_\mathrm{SF}$ values arising from the different building blocks entering the standard semi-classical Wentzel-Kramers-Brillouin formula. Although the uncertainties are large, the trend with mass or neutron numbers are well reproduced and therefore the theory still has predictive power. In this respect, it is also shown that modifications of a few per cent in the pairing strength can have a significant impact on the collective masses leading to uncertainties in the $t_\mathrm{SF}$ values of several orders of magnitude.
description: 22 pages, 17 figures; Minor modifications to previous version
Many-body localization in a disordered quantum Ising chain
Creators: name: Kjäll, Jonas A.
name: Bardarson, Jens H.
name: Pollmann, Frank
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Many-body localization occurs in isolated quantum systems when Anderson localization persists in the presence of finite interactions. Despite strong evidence for the existence of a many-body localization transition a reliable extraction of the critical disorder strength is difficult due to a large drift with system size in the studied quantities. In this work we explore two entanglement properties that are promising for the study of the manybody localization transition: the variance of the half-chain entanglement entropy of exact eigenstates and the long time change in entanglement after a local quench from an exact eigenstate. We investigate these quantities in a disordered quantum Ising chain and use them to estimate the critical disorder strength and its energy dependence. In addition, we analyze a spin-glass transition at large disorder strength and provide evidence for it being a separate transition. We thereby give numerical support for a recently proposed phase diagram of many-body localization with localization protected quantum order [Huse et al. Phys. Rev. B 88, 014206 (2013)].
description: 4+ pages + 1.5 pages appendix, 5 figures
title: Kweku Adoboli at UBS
Creators: name: Moore, Celia
name: Wiley Wakeman, S
Publisher: name: London Business School
Year: 2014
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: The UBS case outlines how individual ambition and lax organisational standards and oversight can lead to consistent unethical behaviour resulting in a crippling loss at a large investment bank. Even though the industry had as recently as 2007 been subject to the ramifications of similar behaviour with Jerome Kerviel's 4.9billion euros loss at Societe Generale, the UBS case highlights how quickly internal controls and ethical concerns can be overlooked. Intense external concerns, driven by a weakening economy, and institutional pressure, due to declining profits, forced internal controls and thorough explanations to be neglected in order to pursue profit. The case also highlights how weak corporate culture and unclear organisational structure can facilitate unethical behaviour. While individuals in Adoboli's role would be expected to lose money on occasion, personal incentive, both from financial gain and organisational advancement, drove Adoboli to conceal his losses from the bank.
description: LBS Case Code: CS-14-001
title: NayaMed (B)
Creators: name: Markides, Costas
name: Duke, Lisa
name: Oyon, Daniel
Publisher: name: London Business School
Year: 2015
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: This is part of a case series. As the Alps disappeared into the darkness through NayaMed's window, the General Manager Aarnav Sendutta considered how to grow his fledgling unit. It was February 2014, and NayaMed, a unit of medical device giant, Medtronic, was just over two years old. It was formed to distribute Medtronic's economy range of heart pacemakers and defibrillators, with regional sales and online technical support. Aarnav was facing two key issues. The first was the perception from Medtronic sales reps that NayaMed would cannibalise their offering. The second issue was how to grow the unit, which currently operated from its Lausanne base in Switzerland, targeting only Italy, Germany and Sweden. The business had grown but was still very small, generating US $4 million in its second year of existence. Aarnav's passion for the NayaMed business was clear, the justification for NayaMed made good business sense, but attempts to grow it were being constrained by organisational issues within the parent company, Medtronic. What could they do?
description: LBS Case Code: CS-15-002
title: Solving the N-Consensus Problem: Combining Clustering and Synchronization
Creators: name: Gering, Stefan
name: Willert, Volker
Publisher: name: IFAC - International Federation of Automatic Control
Year: 2023

description: This article presents a state synchronization method within multi-agent systems upon multiple states. Based on their formation in state space, the agents decide on a clustering and synchronize their states within these clusters. The solution steps for this N-consensus problem, clustering and synchronization, may both be solved entirely in a decentral manner. This is achieved by means of a distributed Variational Bayes to describe the distribution of the agents' positions as a mixture of densities. The entire N-consensus problem is illustrated with graphical probabilistic models whose underlying potential is shown to be maximized when reaching the final N-consensus. An improvement of the overall convergence speed is achieved by a dynamical adaption of the distributed Variational Bayes, which leads to an intertwining of clustering and synchronization.
A compact containment result for nonlinear historical superprocess approximations for population models with trait-dependence
Creators: name: Kliem, Sandra
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J80 (Primary), 60G57, 60J68, 60K35 (Secondary)

description: We consider an approximating sequence of interacting population models with branching, mutation and competition. Each individual is characterized by its trait and the traits of its ancestors. Birth- and death-events happen at exponential times. Traits are hereditarily transmitted unless mutation occurs. The present model is an extension of the model used in [Méléard and Tran, EJP, 2012], where for large populations with small individual biomasses and under additional assumptions, the diffusive limit is shown to converge to a nonlinear historical superprocess. The main goal of the present article is to verify a compact containment condition in the more general setup of Polish trait-spaces and general mutation kernels that allow for a dependence on the parent's trait. As a by-product, a result on the paths of individuals is obtained. An application to evolving genealogies on marked metric measure spaces is mentioned where genealogical distance, counted in terms of the number of births without mutation, can be regarded as a trait. Because of the use of exponential times in the modeling of birth- and death-events the analysis of the modulus of continuity of the trait-history of a particle plays a major role in obtaining appropriate bounds.
description: 13 pages. Shortened version with shortened and streamlined proofs
title: easyCar Reincarnated (F): Putting off Fires and Moving down the Value Chain
Creators: name: Jacobides, Michael
name: Courty, Pascal
Publisher: name: London Business School
Year: 2016
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: In 1999, Stelios Haji-Ioannou and the easyGroup management team considered whether European car rental was a business worth entering. They had an enviable track record when it came to picking market opportunities. Could this be their next success? The case describes easyCar's entry into the European car rental market and subsequent development. It is a versatile set of cases, which can be used individually, as pairs, or as a sequence of cases starting, showing the evolution of a venture from its conception to its troubles and reincarnation. It can also be taught by focusing on one or more episodes which illustrate particular aspects the instructor is interested in.This case can be used either to introduce or recap the core elements of strategy, such as market definition, industry analysis, creating new market spaces, new business model analysis, resources and capabilities. It can also help elucidate more advanced topics; i.e., show where the value lies in the value chain and how a firm should decide its positioning and link with other firms in the ecosystem; identify the challenges with planning for growth and how that links with financial strategy; and raise the upsides and downsides of s'˜Peer-to-Peers's (P2P) models, contrasted with more traditional Business-to-Consumer (B2C) models. More importantly, easyCar can be used to help students evaluate a new business model ex ante, including the role of analogies and the promises and risks of extending a firm's capabilities, and considering adaptation when things turn out worse than expected. The case offers an applied perspective on the use of analogies in strategy formation. It highlights the role of indicators of what is or isn't working in the venture, analogical reasoning and extrapolation notwithstanding.
description: LBS Case Code: CS-05-040
title: Multi Media Mapping Ltd Case (A)
Creators: name: Bates, John
name: Reczek, Cosette
name: Phelan, Sean
Publisher: name: London Business School
Year: 2009
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: It was nearly 10 years since Multi Media Mapping Ltd had gone live with the launch of the Multimap.com website and Sean Phelan, founder and majority shareholder, was facing the classic entrepreneur's dilemma. The company had a successful platform and business model that had made it the market leader in the UK and a highly profitable 'dot-com' survivor of the Web 1.0 generation, but the market was evolving quickly and Sean was convinced that the company's current technology platform didn't have a future. The choice was whether to raise the stakes and bet on the company again in the evolving online mapping industry and emerging Web 2.0 environment, or commit to a process that may lead to the sale of the business. As the company's 10th anniversary party at the Earth Gallery in London's Natural History Museum approached, Sean wondered whether the interests of the company's various stakeholders -  founders, management, option-holding employees and trade investors - were still aligned and how these interests might affect the choices he needed to make. It all seemed a long way from the early days, when he had seen the opportunity to change the way that maps would be used and bootstrapped Multi Media Mapping Ltd into existence.
description: LBS Case Code: CS-20-002
title: Brahma versus Antarctica:  Reversal of Fortune in Brazila's Beer Market
Creators: name: Sull, Donald
Publisher: name: London Business School
Year: 2005
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: The case is set in June 1999 as Marcel Telles, Chairman and Chief Executive Officer of Companhia Cervejaria Brahma (Brahma) 'the largest brewer in Brazil' considers a possible merger with the Antarctica Group (Antarctica), the second-largest Brazilian brewer. If the merger were to be completed, the combined firm would control 75% of Brazil's beer market and forecast pro forma revenues of over $US2.8 billion. The case provides a concise overview of the Brazilian beer market and Brazil's volatile macroeconomic and regulatory context, and summarises the century-long rivalry between Brahma and Antarctica. For a century after their founding, Antarctica led Brahma in terms of market share, profitability, new product introductions and management innovations, although the two brewers were roughly comparable in size. Under Telles' leadership, however, Brahma pulled ahead of its rival in the span of a decade. The case explores the reasons for this dramatic reversal of fortune and describes in detail the actions Telles and his top management team took to change Brahma's culture, set and execute operational improvements, and create real options for future revenue streams.
description: LBS Case Code: CS-04-015
Practopoiesis: Or how life fosters a mind
Creators: name: Nikolić, Danko
Publisher: name: arXiv
Year: 2014
Subjects: subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences

description: The mind is a biological phenomenon. Thus, biological principles of organization should also be the principles underlying mental operations. Practopoiesis states that the key for achieving intelligence through adaptation is an arrangement in which mechanisms laying a lower level of organization, by their operations and interaction with the environment, enable creation of mechanisms lying at a higher level of organization. When such an organizational advance of a system occurs, it is called a traverse. A case of traverse is when plasticity mechanisms (at a lower level of organization), by their operations, create a neural network anatomy (at a higher level of organization). Another case is the actual production of behavior by that network, whereby the mechanisms of neuronal activity operate to create motor actions. Practopoietic theory explains why the adaptability of a system increases with each increase in the number of traverses. With a larger number of traverses, a system can be relatively small and yet, produce a higher degree of adaptive/intelligent behavior than a system with a lower number of traverses. The present analyses indicate that the two well-known traverses-neural plasticity and neural activity-are not sufficient to explain human mental capabilities. At least one additional traverse is needed, which is named anapoiesis for its contribution in reconstructing knowledge e.g., from long-term memory into working memory. The conclusions bear implications for brain theory, the mind-body explanatory gap, and developments of artificial intelligence technologies.
description: Revised version in response to reviewer comments
Risikofaktoren für Arbeitsqualität und psychische Gesundheit: Aktuelle Befunde und ein erstes Fazit
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Kassel
Year: 2012
Subjects: subject: 300
subject: Deutschland
subject: Arbeitsleistung
subject: Gesundheit
subject: Gesundheitsgefährdung

description: Diese Publikation gibt es auch in einer englischen Ausgabe.
Profiling German-speaking socially responsible investors
Creators: name: Dorfleitner, Gregor
name: Utz, Sebastian
Publisher: name: Universität Regensburg
Year: 2014
Subjects: subject: Socially responsible investors, Investment choice preferences, Survey, Multivariate analysis
subject: 330 Wirtschaft
subject: D81
subject: G02
subject: G11

description: The central aim of this paper is to analyze the main motives of investors in allocating their money socially responsibly. The study is based on primary data collected in a survey using an online questionnaire. We apply tests for continuous and categorical data and (ordered) logit models. In a multivariate analysis that investigates determinants of socially responsible investing, we find little influence of the demographic factors gender and investment volume and none of educational level. Furthermore, we show that the regions investors allocate their money to are significant as well as the preference towards the order of return, risk and liquidity. Moreover, there seems to be a gap between supply and demand of socially responsible investments. Additionally, there are indications that a very important inducement for socially responsible investing is the expectation of high financial performance. This study broadens the scope of the literature by providing novel empirical evidence for the German-speaking market.
title: Amazon.com: Staying a step ahead (2020)
Creators: name: Birkinshaw, Julian
name: Duke, Lisa
Publisher: name: London Business School
Year: 2020
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: This case traces the rise and rise of Amazon.com, the second company after Apple to hit a trillion dollar market cap. The growth of Amazon is described, from its origins back in 1995 through to 2016. The case intentionally provides a lot of detail on specific new products and services created over this twenty year period, and how many of these were highly risky bets, and some were failures. For example: there is a discussion of how Amazon survived the original dotcom bubble bursting by deliberately reducing investment and showing a profit for the first time; the origins of Amazon Prime, Amazon marketplace, the Kindle, Amazon Web Services, and Amazon video are all described with enough detail for students to ask, why did they do this? What was the bigger purpose behind these moves?The case also talks about Amazon's management principles and organization culture. For example, one of Bezos's guiding principles was to 'obsess over customers' meaning always seeking out ways to improve the quality of their buying experience and offering additional services and products to meet their evolving needs. There is also a discussion of the 'always day one' culture, the 'willingness to be misunderstood' and the style of leadership Bezos exhibits.
description: LBS Case Code: CS-13-016
title: Changing the Fortunes of E.ON's Corporate Customer Business (B)
Creators: name: Jacobides, Michael
name: Merrick, Adrian
Publisher: name: London Business School
Year: 2010
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: This case details UK energy supplier E.ON's business turnaround from 2008. The company operated generation, distribution and retail businesses, with separately run sales and customer service operations. Following the departure of the heads of the sales and the customer service divisions, Adrian Merrick was tasked with bringing the two areas of the business together, running corporates as an end-to-end business and dealing with the issues faced by the business as a whole. In essence, this entailed resolving three key questions: What was the right strategy for E.ON in the corporates market? How could profitability be improved in the short term? How could the steady increase in debt be stopped?
description: LBS Case Code: CS-11-042
title: Desso (A): Taking on the Sustainability Challenge
Creators: name: Ioannou, Ioannis
name: Ody-Brasier, Amandine
Publisher: name: London Business School
Year: 2011
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: This is part of a case series. This case describes the strategic transformation of DESSO, a Dutch manufacturer of carpet tiles and flooring solutions. The first part of the case describes the difficult situation in which the company found itself in the early 2000s, following a series of changes in ownership. It focuses on the strategic vision developed by Stef Kranendijk, the company's new CEO, as he takes over the company in 2007. An important element of this vision is to make sustainability a key driver of DESSO's innovation strategy. The case highlights the process that led DESSO to consider a Cradle to Cradle(R) approach as well as the potential issues this new orientation raised for important stakeholders, including employees, board members, customers and suppliers. The second part of the case provides some updates as to DESSO's situation in 2010. It describes the short-term results of Kranendijk's strategic vision and how it transformed DESSO's business model. It also gives details on the implementation of the new strategy and the challenges still ahead.
description: LBS Case Code: CS-11-029
Mode-locked Bloch oscillations in a ring cavity
Creators: name: Samoylova, M.
name: Piovella, N.
name: Hunter, D.
name: Robb, G. R. M.
name: Bachelard, R.
name: Courteille, Ph. W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We present a new technique for stabilizing and monitoring Bloch oscillations of ultracold atoms in an optical lattice under the action of a constant external force. In the proposed scheme, the atoms also interact with a unidirectionally pumped optical ring cavity whose one arm is collinear with the optical lattice. For weak collective coupling, Bloch oscillations dominate over the collective atomic recoil lasing instability and develop a synchronized regime in which the atoms periodically exchange momentum with the cavity field.
description: 7 pages, 5 figures
title: Vision assisted disassembly using a dexterous hand-arm-system: An example and experimental results
Creators: name: Weigl, Alexandra
name: Seitz, Matthias
Publisher: name: IFAC - International Federation of Automatic Control
Year: 2023

description: Future applications in automation of non-destructive disassembly processes - necessary and important for re-use of components - require highly sensorized and dexterous robot systems. The main elements of the presented system are a disassembly sequence planner using special elementary disassembly operations, a redundant hand-arm-system with fifteen degrees of freedom supplied by a six-axes robot and a three-fingered gripper, and a vision system used for offline grasp and motion planning as well as for online supervision. Besides a description of the overall system structure and explanation of the underlying ideas for special disassembly operations, the presentation of first results and experiences from disassembling some parts of a video camera recorder will be one of the centred points to be discussed.
De novo design of new chemical entities with AI methods
Creators: name: Korshunova, Maria
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: Computational Biology

description: This thesis describes novel deep generative neural networks and their applications for the de novo design of molecules with optimized properties. It discusses the background and motivation for using deep generative models for de novo drug design, covering the advantages and limitations of existing techniques such as virtual screening of molecular libraries, genetic algorithms, and combinatorial enumeration of molecules from a set of building blocks. Next, it describes novel deep generative neural network architectures for producing molecules in three commonly used molecular representations – SMILES strings, 2D molecular graphs, and 3D molecular graphs, with details of the design, implementation, and computational experiments. It continues with a slight detour portraying how a generative model can provide an empirical estimate for the number of bioactive compounds in the chemical space and describes the experiment performed to obtain such an estimate. Next, it introduces Reinforcement Learning based strategy to optimize the values of a property of interest for generated molecules. It also proposes several heuristics for more efficient exploration of the chemical space. Finally, it describes how the proposed models and optimization algorithms were used to virtually design and then experimentally confirm novel hits for multiple kinase proteins.
On the slice genus and some concordance invariants of links
Creators: name: Cavallo, Alberto
Publisher: name: arXiv
Year: 2014
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We introduce a new class of links for which we give a lower bound for the slice genus $g_*$, using the generalized Rasmussen invariant. We show that this bound, in some cases, allows one to compute $g_*$ exactly; in particular, we compute $g_*$ for torus links. We also study another link invariant: the strong slice genus $g_*^*$. Studying the behaviour of a specific type of cobordisms in Lee homology, a lower bound for $g_*^*$ is also given.
Regular graphs maximize the variability of random neural networks
Creators: name: Wainrib, Gilles
name: Galtier, Mathieu
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: In this work we study the dynamics of systems composed of numerous interacting elements interconnected through a random weighted directed graph, such as models of random neural networks. We develop an original theoretical approach based on a combination of a classical mean-field theory originally developed in the context of dynamical spin-glass models, and the heterogeneous mean-field theory developed to study epidemic propagation on graphs. Our main result is that, surprisingly, increasing the variance of the in-degree distribution does not result in a more variable dynamical behavior, but on the contrary that the most variable behaviors are obtained in the regular graph setting. We further study how the dynamical complexity of the attractors is influenced by the statistical properties of the in-degree distribution.
A magic pyramid of supergravities
Creators: name: Anastasiou, A.
name: Borsten, L.
name: Duff, M. J.
name: Hughes, L. J.
name: Nagy, S.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Differential Geometry (math.DG)
subject: Group Theory (math.GR)
subject: Rings and Algebras (math.RA)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 83E50, 17A75, 17B25

description: By formulating N = 1, 2, 4, 8, D = 3, Yang-Mills with a single Lagrangian and single set of transformation rules, but with fields valued respectively in R,C,H,O, it was recently shown that tensoring left and right multiplets yields a Freudenthal-Rosenfeld-Tits magic square of D = 3 supergravities. This was subsequently tied in with the more familiar R,C,H,O description of spacetime to give a unified division-algebraic description of extended super Yang-Mills in D = 3, 4, 6, 10. Here, these constructions are brought together resulting in a magic pyramid of supergravities. The base of the pyramid in D = 3 is the known 4x4 magic square, while the higher levels are comprised of a 3x3 square in D = 4, a 2x2 square in D = 6 and Type II supergravity at the apex in D = 10. The corresponding U-duality groups are given by a new algebraic structure, the magic pyramid formula, which may be regarded as being defined over three division algebras, one for spacetime and each of the left/right Yang-Mills multiplets. We also construct a conformal magic pyramid by tensoring conformal supermultiplets in D = 3, 4, 6. The missing entry in D = 10 is suggestive of an exotic theory with G/H duality structure F4(4)/Sp(3) x Sp(1).
description: 30 pages, 6 figures. Updated to match published version. References and comments added
title: Fatima Akilu: The rise of a quiet leader (A)
Creators: name: Peterson, Randall
Publisher: name: London Business School
Year: 2021
Subjects: subject: FOS: Economics and business
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: In 2015, Fatima Akilu found herself sitting at the kitchen table with her sister, shocked and saddened by what has just happened to her, wondering what to do next. Should she fight to defend her reputation? Or return to a quiet life away from the big government role she has just been fired from?  Fatima Akilu never intended to be a leader. But in 2012, she was appointed Director for Behavioural Analysis and Strategy at Nigeria's Office of the National Security Adviser (NSA), charged with leading the country's efforts to combat the effects of the violent extremism of Boko Haram and other terrorist groups.
description: LBS Case Code: CS-21-009
Direct Neural Conversion of Adult Human Fibroblasts: Generation and Transplantation of Dopaminergic Neurons for Cell-Based Replacement Therapy
Creators: name: Shrigley, Shelby
name: Drouin-Ouellet, Janelle
name: Pereira, Maria
name: Hoban, Deirdre B
name: Cardoso, Tiago
name: Parmar, Malin
Publisher: name: Zenodo
Year: 2017

description: Cell-based replacement therapy has great potential to improve the clinical outcome of Parkinson’s disease (PD). Induced neurons are a unique resource negating safety concerns associated with pluripotency, as well as ethical concerns with embryonic derived cells, whilst allowing for patient specific cells or matched donors. We have previously shown that dopaminergic (DA) neuronal fate could be generated from fetal fibroblasts using forced expression of Ascl1 and specific DA fate determinants, however this early protocol showed low efficiency when converting adult fibroblasts. Here we build on our reprogramming method to convert adult fibroblasts into induced dopaminergic neurons (iDANs) with a new combination of transcription factors combined with a REST knock-down. Generated iDANS show the presence of genes normally expressed in DA neurons including TH, NURR1 and PITX3. We are now investigating survival of iDANs following transplantation using different time points post-transduction in a rodent model of PD. Results provide a more robust and efficient protocol for the generation of iDANs and will help to pave the way for future research assessing their potential for brain repair.
A Planar Five‐Membered Aromatic Ring Stabilized by Only Two π‐Electrons
Creators: name: Kysliak, Oleksandr
name: Schreiner, Simon
name: Grabicki, Niklas
name: Liebing, Phil
name: Weigend, Florian
name: Dumele, Oliver
name: Kretschmer, Robert
Publisher: name: Humboldt-Universität zu Berlin
Year: 2022
Subjects: subject: Aromaticity
subject: Gallium
subject: Inorganic Ring Systems
subject: NICS
subject: 540 Chemie und zugeordnete Wissenschaften

description: Many chemicals known today are partially or fully aromatic, since a ring framework experiences additional stabilization through the delocalization of π‐electrons. While aromatic rings with equal numbers of π‐electrons and ring atoms such as benzene are particularly stable, those with the minimally required two π‐electrons are very rare and yet remain limited to three‐ and four‐membered rings if not stabilized in the coordination sphere of heavy metals. Here we report the facile synthesis of a dipotassium cyclopentagallene, a unique example of a five‐membered aromatic ring stabilized by only two π‐electrons. Single‐crystal X‐ray diffraction revealed a planar Ga5 ring with almost equal gallium–gallium bond lengths, which together with computational and spectroscopic data confirm its aromatic character. Our results prove that aromatic stabilization goes far beyond what has previously been assumed as minimum π‐electron count in a five‐atom ring fragment.
数据采集、分析及审查的流程.docx
Creators: name: wang, yuting
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 520302
subject: Clinical psychology
classificationCode: 520303
subject: Counselling psychology
classificationCode: 520304
subject: Health psychology

description: 目的：考察心理热线援助在新冠肺炎疫情中的使用模式与效果。方法：对13名参与热线援助的注册心理师进行半结构化访谈，采用共识性质性研究的方法(consensual qualitative research)对访谈誊录稿进行分析。结果：数据描述并解释了十个主题：疫情中热线援助的目标、策略、技术和指导原则，援助热线的特点、援助者的角色、求助者的特征、援助的效果与评估，以及援助有效性的影响因素。结论：新冠肺炎疫情中的心理热线援助模式在目标、策略与方法上围绕两个核心要素而建立，一是处理因疫情与疫情防控所引起的恐惧、焦虑与抑郁情绪；二是有效应对疫情中的实际困难。
The Cos4Cloud final event presentation: its legacy for the citizen science community
Creators: name: Liñán, Sonia
name: Soacha, Karen
name: Piera, Jaume
Publisher: name: Zenodo
Year: 2023
Subjects: citizen science
co-design
citizen observatories
biodiversity
environment
open data
EOSC
European Open Science Cloud
technology
education
agile methodology

description: To wrap up over three years of the project and its community, Cos4Cloud and ECSA co-organised a final event for everyone interested to learn about the project's main achievements, discover how to use Cos4Cloud's products and celebrating the community that has actively contributed to the project. The event was divided into two main parts; during the first one, Jaume Piera, the Cos4Cloud coordinator and Institut de Ciències del Mar – CSIC researcher, explained our journey & contributions to citizen science, citizen observatories & the European Open Science Cloud (EOSC). More information and the link to the recording in this link.
Baryonic and dark matter distribution in cosmological simulations of spiral galaxies
Creators: name: Mollitor, Pol
name: Nezri, Emmanuel
name: Teyssier, Romain
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We study three cosmological hydrodynamical simulations of Milky Way(MW)-sized halos including a comparison with the dark matter(DM)-only counterparts. We find one of our simulated galaxies with interesting MW-like features. Thanks to a consistently tuned star formation rate and supernovae feedback we obtain an extended disk and a flat rotation curve with a satisfying circular velocity and a reasonable DM density in the solar neighbourhood. Mimicking observational methods, we re-derive the stellar mass and obtain stellar-to-halo mass ratios reduced by more than 50\%. We show the interaction between the baryons and the dark matter which is first contracted by star formation and then cored by feedback processes. Indeed, we report an unprecedentedly observed effect in the DM density profile consisting of a central core combined with an adiabatic contraction at larger galactic radii. The cores obtained are typically $\sim$ 5 kpc large. Moreover, this also impacts the DM density at the solar radius. In our simulation resembling most to the MW, the density is raised from 0.23 GeV/cm$^3$ in the dark matter only run to 0.36 GeV/cm$^3$ (spherical shell) or 0.54 GeV/cm$^3$ (circular ring) in the hydrodynamical run. Studying the subhalos, the dark matter within luminous satellites is also affected by baryonic processes and exihibits cored profiles whereas dark satellites are cuspy. We find a shift in mass compared to DM-only simulations and obtain, for halos in the lower MW mass range, a distribution of luminous satellites comparable to the MW spheroidal dwarf galaxies.
description: matches version accepted in MNRAS, 17 pages, 15 figures, text improved, satellite section extended
Spin-Precession: Breaking the Black Hole--Neutron Star Degeneracy
Creators: name: Chatziioannou, Katerina
name: Cornish, Neil
name: Klein, Antoine
name: Yunes, Nicolas
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Mergers of compact stellar remnant are prime targets for the LIGO/Virgo gravitational wave detectors. One hopes that the gravitational wave signals from these merger events can be used to study the mass and spin distribution of stellar remnants, and provide information about black hole horizons and the material properties of neutron stars. However, it has been suggested that degeneracies in the way that the star's mass and spin are imprinted in the waveforms may make it impossible to distinguish between black holes and neutron stars. Here we show that the precession of the orbital plane due to spin-orbit coupling breaks the mass-spin degeneracy, and allows us to distinguish between standard neutron stars and alternative possibilities, such as black holes or exotic neutron stars with large masses and spins.
description: 5 pages, 4 figures, published version, major modifications
Counting solutions of quadratic congruences in several variables revisited
Creators: name: Tóth, László
Publisher: name: arXiv
Year: 2014
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11D79, 11A25, 11N37

description: Let $N_k(n,r,\boldsymbol{a})$ denote the number of incongruent solutions of the quadratic congruence $a_1x_1^2+\ldots+a_kx_k^2\equiv n$ (mod $r$), where $\boldsymbol{a}=(a_1,\ldots,a_k)\in {\Bbb Z}^k$, $n\in {\Bbb Z}$, $r\in {\Bbb N}$. We give short direct proofs for certain less known compact formulas on $N_k(n,r,\boldsymbol{a})$, valid for $r$ odd, which go back to the work of Minkowski, Bachmann and Cohen. We also deduce some other related identities and asymptotic formulas which do not seem to appear in the literature.
description: 20 pages, revised, asymptotic formulas improved/added
Stepping and crowding of molecular motors: statistical kinetics from an exclusion process perspective
Creators: name: Ciandrini, Luca
name: Romano, M. Carmen
name: Parmeggiani, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Subcellular Processes (q-bio.SC)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Motor enzymes are remarkable molecular machines that use the energy derived from the hydrolysis of a nucleoside triphosphate to generate mechanical movement, achieved through different steps that constitute their kinetic cycle. These macromolecules, nowadays investigated with advanced experimental techniques to unveil their molecular mechanisms and the properties of their kinetic cycles, are implicated in many biological processes, ranging from biopolymerisation (e.g. RNA polymerases and ribosomes) to intracellular transport (motor proteins such as kinesins or dyneins). Although the kinetics of individual motors is well studied on both theoretical and experimental grounds, the repercussions of their stepping cycle on the collective dynamics still remains unclear. Advances in this direction will improve our comprehension of transport process in the natural intracellular medium, where processive motor enzymes might operate in crowded conditions. In this work, we therefore extend the current statistical kinetic analysis to study collective transport phenomena of motors in terms of lattice gas models belonging to the exclusion process class. Via numerical simulations, we show how to interpret and use the randomness calculated from single particle trajectories in crowded conditions. Importantly, we also show that time fluctuations and non-Poissonian behavior are intrinsically related to spatial correlations and the emergence of large, but finite, clusters of co-moving motors. The properties unveiled by our analysis have important biological implications on the collective transport characteristics of processive motor enzymes in crowded conditions.
description: 9 pages, 6 figures, 2 supplementary figures