title: ÐÐ½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½ÑÐµ ÑÐ²Ð¾Ð¹ÑÑÐ²Ð° ÑÐ»Ð¾Ð¶Ð½ÑÑ ÑÑÐ¸ÑÐ¾Ð² N-ÑÐµÐ½Ð¸Ð»Ð¸Ð¼Ð¸Ð´Ð¾Ð²
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Antimicrobial properties of esters of N-phenylimides
Creators: name: Ð§Ð¶Ð°Ð¾ Ð¤Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2022
Subjects: Ð¿Ð¾Ð»Ð¸ÑÑÐ¾ÑÐ°Ð»ÐºÐ¸Ð»Ð¾Ð²ÑÐµ ÑÑÐ¸ÑÑ N-Ð¼Ð°Ð»ÐµÐ¾Ð¿Ð¸Ð¼Ð°ÑÐ¸Ð¼Ð¸Ð´Ð° Ð»ÐµÐ¹ÑÐ¸Ð½Ð°
ÑÐ°Ð»Ð»Ð¾Ð²Ð°Ñ ÐºÐ°Ð½Ð¸ÑÐ¾Ð»Ñ
Ð°Ð½ÑÐ¸Ð¼Ð¸ÐºÑÐ¾Ð±Ð½Ð°Ñ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ
Ð¼Ð°Ð»ÐµÐ¾Ð¿Ð¸Ð¼Ð°ÑÐ¾Ð²Ð°Ñ ÐºÐ¸ÑÐ»Ð¾ÑÐ°
polyfluoroalkyl esters of N-maleopimarimide of leucine
tallo rosin
antimicrobial activity
maleopimaric acid

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description: This work is devoted to the study of the antimicrobial properties of new polyfluoroalkyl ethers of N-maleopimarimide, as well as the calculation of the biological activity (BA) of the studied compounds using the software package PASS online. The following tasks were solved within the framework of the final work: 1) Selection of the objects of study: polyfluoroalkyl ethers of N-maleopimarimide leucine and microorganisms. 2) Synthesis of new polyfluoroalkyl ethers of N-maleopimarimide leucine. 3) Preparation of nutrient media for microorganisms. 4) Incubation of microorganisms used in the work. 5) Preparation of diluted solutions of polyfluoroalkyl ethers of N-maleopimarimide leucine. 6) Determination of antimicrobial properties of polyfluoroalkyl ethers of N-maleopimarimide leucine. 7) Calculation of the biological activity (BA) of compounds using the PASS online software package. This work was carried out in the laboratory of organic synthesis of Graduate School of Biotechnology and Food Technology, where the synthesis and antimicrobial properties of new polyfluoroalkyl esters of N-maleopimarimide leucine were investigated. As a result of the study, it was found that polyfluoroalkyl esters of N-maleopymarimide leucine exhibit the greatest inhibitory effect against cells of microorganisms Bacillus subtilis and Rhodotorula rubra and have no effect on cells of Escherichia coli, Saccharomyces boulardii and Candida tropicalis.