cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Relationships between water quality and stream invertebrate assemblages of Eastern Ontario and Western Quebec.
Creators: name: Lalonde, Benoît.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Biology, Ecology.

description: Forty-seven riffle zones from 21 streams of Eastern Ontario and Western Quebec were sampled in 1998 to describe how characteristics of the benthic invertebrate assemblage (abundance, taxa richness and size distribution) varied as a function of water quality parameters (conductivity, TP, SRP, TSS, NO3+NO2, NH3, TKN, Cl-, SO42-) along a gradient of watershed development. A principal components analysis on water quality parameters revealed that there were two groups of correlated water quality variables that explained the majority of the variability among sites. The first group of variables included chloride, sulfate, nitrate+nitrite and conductivity and represented a gradient of urbanization while the second group represented nutrients and included: soluble reactive phosphorus, total phosphorus, ammonia, total suspended solids and total Kjeldahl nitrogen. Simple and multiple regression models predicting invertebrate assemblage characteristics were fitted using water quality principal components scores as independent variables. Overall, invertebrate assemblage characteristics were related to both groups of water quality variables. Abundances per taxon and size classes generally increased with increased nutrients, and overall abundance and the ratio of abundances of sensitive to tolerant taxa declined with increasing chloride, sulfate, nitrate+nitrite and conductivity. Existing information suggests that the water quality gradient found in these streams is more a reflection of anthropogenic sources than the result of geological differences. Therefore, it appears that human activities affect the distribution and abundance of invertebrates in this region. However our models did not explain a good proportion of the variability. It would seem that stream invertebrates of the Ottawa valley are also affected by other parameters that have yet to be identified.
Mitigating Pattern Collapse in High-Resolution EUV Lithography Using the Organic Dry Development Rinse (O-DDR) Process
Creators: name: Heo, Seonggil
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 401806
subject: Nanomanufacturing

description: Pattern collapse emerges as a key factor leading to the failure of photoresist patterns in high-resolution EUV lithography. Its significance escalates as feature sizes decrease and pitches become smaller, transitioning to high-NA EUV, potentially leading to challenges with regards to resolution. Pattern collapse arises from capillary forces acting on the resist surface during wafer drying. Consequently, the optimal strategy to mitigate pattern collapse involves eliminating any drying steps post-lithography processing. In this study, we introduce the O-DDR process for spin-on MOR, effectively eliminating capillary force and eradicating the pattern collapse issue without tone inversion. This involves dispensing O-DDR material instead of employing a spin-drying developer, without introducing any extra processing steps. After the dry etching process, we observe that the resist patterns, such as pitch 32 nm pillars and pitch 28 nm line and space, remain intact without any collapse at small pitches or low doses. Furthermore, we analyze the O-DDR process, intending to expand the window for a failure-free process with pitch 32 nm pillars and pitch 28 nm line and space in EUV lithography
Clustering properties of TGSS radio sources
Creators: name: Dolfi, Arianna
name: Branchini, Enzo
name: Bilicki, Maciej
name: Balaguera-Antolínez, Andres
name: Prandoni, Isabella
name: Pandit, Rishikesh
Publisher: name: Swinburne
Year: 2024

description: We investigate the clustering properties of radio sources in the Alternative Data Release 1 of the TIFR GMRT Sky Survey (TGSS), focusing on large angular scales, where previous analyses have detected a large clustering signal. After appropriate data selection, the TGSS sample we use contains similar to 110 000 sources selected at 150MHz over similar to 70% of the sky. The survey footprint is largely superimposed on that of the NRAO VLA Sky Survey (NVSS) with the majority of TGSS sources having a counterpart in the NVSS sample. These characteristics make TGSS suitable for large-scale clustering analyses and facilitate the comparison with the results of previous studies. In this analysis we focus on the angular power spectrum, although the angular correlation function is also computed to quantify the contribution of multiple-component radio sources. We find that on large angular scales, corresponding to multipoles 2 <= l <= 30, the amplitude of the TGSS angular power spectrum is significantly larger than that of the NVSS. We do not identify any observational systematic effects that may explain this mismatch. We have produced a number of physically motivated models for the TGSS angular power spectrum and found that all of them fail to match observations, even when taking into account observational and theoretical uncertainties. The same models provide a good fit to the angular spectrum of the NVSS sources. These results confirm the anomalous nature of the TGSS large-scale power, which has no obvious physical origin and seems to indicate that unknown systematic errors are present in the TGSS dataset.
Low renal but high extrarenal phenotype variability in Schimke immuno-osseous dysplasia
Creators: name: Lipska-Zietkiewicz, Beata S.
name: Gellermann, Jutta
name: Boyer, Olivia
name: Gribouval, Olivier
name: Zietkiewicz, Szymon
name: Kari, Jameela A.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Schimke immuno-osseous dysplasia (SIOD) is a rare multisystem disorder with early mortality and steroid-resistant nephrotic syndrome (SRNS) progressing to end-stage kidney disease. We hypothesized that next-generation gene panel sequencing may unsurface oligosymptomatic cases of SIOD with potentially milder disease courses. We analyzed the renal and extrarenal phenotypic spectrum and genotype-phenotype associations in 34 patients from 28 families, the largest SMARCAL1-associated nephropathy cohort to date. In 11 patients the diagnosis was made unsuspectedly through SRNS gene panel testing. Renal disease first manifested at median age 4.5 yrs, with focal segmental glmerulosclerosis or minimal change nephropathy on biopsy and rapid progression to end-stage kidney disease (ESKD) at median age 8.7 yrs. Whereas patients diagnosed by phenotype more frequently developed severe extrarenal complications (cerebral ischemic events, septicemia) and were more likely to die before age 10 years than patients identified by SRNS-gene panel screening (88 vs. 40%), the subgroups did not differ with respect to age at proteinuria onset and progression to ESKD. Also, 10 of 11 children diagnosed unsuspectedly by Next Generation Sequencing were small at diagnosis and all showed progressive growth failure. Severe phenotypes were usually associated with biallelic truncating mutations and milder phenotypes with biallelic missense mutations. However, no genotype-phenotype correlation was observed for the renal disease course. In conclusion, while short stature is a reliable clue to SIOD in children with SRNS, other systemic features are highly variable. Our findings support routine SMARCAL1 testing also in non-syndromic SRNS.
Ocular transient receptor potential channel function in health and disease
Creators: name: Reinach, Peter S.
name: Mergler, Stefan
name: Okada, Yuka
name: Saika, Shizuya
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: Transient receptor potential ion channels
subject: Calcium
subject: Retina
subject: Cornea
subject: Uvea
subject: Lens
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Transient receptor potential (TRP) channels sense and transduce environmental stimuli into Ca2+ transients that in turn induce responses essential for cell function and adaptation. These non-selective channels with variable Ca2+ selectivity are grouped into seven different subfamilies containing 28 subtypes based on differences in amino acid sequence homology. Many of these subtypes are expressed in the eye on both neuronal and non-neuronal cells where they affect a host of stress-induced regulatory responses essential for normal vision maintenance. This article reviews our current knowledge about the expression, function and regulation of TRPs in different eye tissues. We also describe how under certain conditions TRP activation can induce responses that are maladaptive to ocular function. Furthermore, the possibility of an association between TRP mutations and disease is considered. These findings contribute to evidence suggesting that drug targeting TRP channels may be of therapeutic benefit in a clinical setting. We point out issues that must be more extensively addressed before it will be possible to decide with certainty that this is a realistic endeavor. Another possible upshot of future studies is that disease process progression can be better evaluated by profiling changes in tissue specific functional TRP subtype activity as well as their gene and protein expression.
ПУТИ ВНЕДРЕНИЯ НОВЫХ ТЕХНОЛОГИЙ В ИННОВАЦИОННЫЙ МЕНЕДЖМЕНТ
Creators: name: Мустафоев, Асадбек
Publisher: name: Zenodo
Year: 2024

description: В данной статье анализируются способы инновационного менеджмента по внедрению новых технологий и их влияние на эффективность предприятия. Рассмотрена важность внедрения новых технологий, основные принципы и стратегии инновационного менеджмента. Также обсуждается важность технологических исследований, адаптации и процессов обучения сотрудников, а также способы автоматизации процессов и создания новых продуктов. Результаты статьи показывают положительное влияние внедрения новых технологий на общую эффективность, конкурентоспособность и финансовые результаты предприятия.
Evaluation of the CPR video decision aid with patients with end stage renal disease
Creators: name: Kapell Brown, Cherie
name: Kryworuchko, Jennifer
name: Martin, Wanda
Publisher: name: BioMed Central
Year: 2018

description: Background: People with end stage renal disease (ESRD) face important health-related decisions concerning end-of-life care and the use of life-support technologies. While people often want to be involved in making decisions about their health, there are many challenges. People with advanced illness may have limited or wavering ability to participate fully in decision-making conversations – or lack decisional capacity for making decisions. Additionally, they may have a limited understanding of CPR and tend to receive inconsistent information on the process and outcome of CPR. Unfortunately, these discussions are often avoided. Shared decision-making approaches are an approach to overcoming these challenges. The objectives of this research was to design, test, and analyze a novel CPR video decision aid (VDA) with nephrology patients and their families in a clinical setting. Methods: The Interprofessional Shared Decision-making Model was used as a framework to guide the research. A prospective quasi-experimental design included pre/posttest measures of knowledge and confidence in decision-making, and posttest only measure of uncertainty about the decision. Results: Participant knowledge about CPR increased from a mean score of 4.8/9 (standard deviation [SD] = 1.65) before viewing the video to 7.5/9 (SD = 1.40) (p = 0.000) after viewing the video. Decisional self-efficacy improved slightly from 84% pre intervention (SD 17.04, range 20–100) to 86% after the intervention (SD 14.13, range 39–100) (p = 0.005) for patient participants. Before the intervention, most patients (43/49; 86%) had an order to have CPR in the physician orders and very few (7/49; 14%) had an order not to have CPR. Immediately after viewing the CPR-VDA and completing the values clarification worksheet, fewer 28/49 (57%) chose to have CPR, 13 (27%) chose not to have CPR and 8 (16%) were unsure. Conclusions: The CPR-VDA was feasible and acceptable to patients with ESRD, their families and the healthcare team. The CPR-VDA positively affected decision-making: improving patient and family knowledge about CPR, clarity of values, patients’ decisional self-efficacy, the congruence between documented physician’s orders and patient choice, quality of communication about CPR, while reducing decisional conflict (uncertainty) amongst patients, families, and physicians.
Neuronal control of catecholamine release in the rainbow trout (Oncorhynchus mykiss)
Creators: name: Montpetit, Colin J
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Biology, Neuroscience.
subject: Biology, Animal Physiology.

description: The aim of this thesis was to study aspects of the neuronal control of catecholamine secretion in a teleost, the rainbow trout. The development and validation of a nerve stimulation technique made it possible to determine that a portion of the neuronal control of catecholamine release, which prevailed at low frequency stimulation, could be attributed to vasoactive intestinal polypeptide (VIP) and/or pituitary adenylate cyclase activating polypeptide (PACAP). On the other hand, cholinergic stimulation predominated during higher levels of neuronal activity. Fluorescent histochemical techniques in combination with pharmacological approaches provided direct evidence that VIP and PACAP can elicit the secretion of adrenaline, only, from the chromaffin tissue via specific VIP binding sites that exhibited properties of VPAC receptors. Using in situ perfused posterior cardinal vein preparations, evidence was provided that while the nicotinic receptor appears to be the predominant pathway mediating the effects of acetylcholine on catecholamine secretion, muscarinic receptor stimulation may augment the cellular response to nicotinic receptor activation. Under extreme conditions, muscarinic receptors may directly elicit the secretion of catecholamines. The impact of extracellular catecholamines on catecholamine secretion from chromaffin cells was also investigated. Results revealed that the mechanisms of adrenergic inhibition of catecholamine secretion in response to cholinergic stimulation include activation of chromaffin cell membrane beta2-receptors and presynaptic alpha2-adrenergic receptors. However, catecholamine release in response to VIP appears to be insensitive to the adrenergic negative feedback mechanisms. Finally, despite the rapid progress in cDNA cloning, molecular information on the receptors mediating the effects of VIP and PACAP in fish is scant. In this thesis, I report preliminary findings of the cloning of the trout PAC1, VPAC1, and VPAC2 receptors from brain cDNA. In summary, VIP and PACAP appear to function as neurotransmitters in the neuronal regulation of catecholamine release in this species. The apparent complexity of the mechanisms regulating the secretion of catecholamines from trout chromaffin cells may reflect the precise control required for these hormones to play their role in physiological and biochemical homeostasis in these organisms.
Vorsorgende Leistungen der Wasserversorger
Creators: name: Richter, Simone
Publisher: name: My University
Year: 2015

description: Im Bundesanzeiger vom 28. August 2014 veröffentlichten das Bundesministerium für Umwelt, Naturschutz, Bau und Reaktorsicherheit (BMUB) und das Bundesministerium für Gesundheit (BMG) einen Katalog zu den vorsorgenden Leistungen im Gewässer- und Gesundheitsschutz. Der Katalog wurde gemeinsam mit den Branchenverbänden Bundesverband der Energie- und Wasserwirtschaft e.V. (BDEW), Deutscher Verein des Gas- und Wasserfaches e.V. (DVGW) und dem Verband kommunaler Unternehmen e. V. (VKU) entwickelt. Ziel des Kataloges ist es, Leistungen, die Wasserversorger über ihre eigentlichen Kernaufgaben hinaus im Vorsorgebereich erbringen, als unverzichtbaren Bestandteil der Daseinsvorsorge zu erhalten. Der Vorsorgegrundsatz ist von der Leitidee geprägt, Belastungen der Gewässer von vornherein zu vermeiden, um die damit verbundenen Risiken für die menschliche Gesundheit und die Umwelt zu minimieren. Mit entsprechenden Maßnahmen unterstützen die Wasserversorger in Deutschland nachhaltig den Gewässerschutz und fördern den sorgsamen Umgang mit Wasser.Quelle: Umweltbundesamt
description: In the German Federal Gazette of 28th August, 2014 the Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety (BMUB) and the Ministry of Health (BMG) published a catalogue of precautionary services for environmental and health protection. This catalogue was developed in cooperation with the water supply associations BDEW (German Association of Energy and Water Industries), DVGW (German Technical and Scientific Association for Gas and Water) and VKU (German Association of Local Utilities). Water suppliers provide - beyond their core mandate ? a range of indispensable precautionary services for environmental and health protection. It is a special environmental and health concern to keep these services within the portfolio of the water suppliers. The precautionary principle follows the idea to avoid pollution of waters and to minimize the risks to human health and the environment from the outset. Implementing appropriate measures water supply companies support and enhance water protection in Germany in a sustainable way.Quelle: Umweltbundesamt
Characterization of epitopes on the rabies virus glycoprotein by selection and analysis of escape mutants
Creators: name: Fallahi, Firouzeh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Biology, Microbiology.
subject: Biology, Zoology.
subject: Chemistry, Biochemistry.

description: Rabies virus, a negative sense single-stranded RNA virus, is the type member of the genus Lyssavirus of the Rhabdoviridae . The glycoprotein (G), which projects from the surface of the lyssavirus particle, is the only protein known to be capable of eliciting the production of neutralizing antibodies and knowledge of the antigenic nature of this protein is therefore important. Five different antigenic sites have been mapped on the G protein. In this study, the isolation of mutants resisting antibody neutralization (escape mutants) was attempted by a selection strategy employing three distinct strains of rabies: Evelyn Rokitnicki Abelseth (ERA), Big Brown Bat (BBB), and Silver Haired Bat (SHB). No escape mutants were generated from BBB and SHB but a total of seven independent ERA mutants were recovered using monoclonal antibodies (Mabs) directed against antigenic sites I and IIIa of the glycoprotein. (Abstract shortened by UMI.)
Die Nutzung natürlicher Ressourcen
Creators: name: Lutter, Stephan
name: Kreimel, Julia
name: Giljum, Stefan
name: Manstein, Christopher
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: Ressourcenverbrauch
Ressourceneffizienz
Nachhaltigkeit

description: Deutschland hat sich mit dem Ressourceneffizienzprogramm (ProgRess) zum schonenden Umgang mit natürlichen Ressourcen bekannt. Das Umweltbundesamt unterstützt die Umsetzung von ProgRess unter anderem mit diesem Bericht zur Nutzung natürlicher Ressourcen in Deutschland, der nach 2016 und 2018 zum dritten Mal erscheint. Der Bericht analysiert neue Zahlen über die Zusammenhänge von Rohstoffentnahme, Rohstoffhandel, der Rolle der Wirtschaft und des Konsums. Außerdem werden Umweltauswirkungen der Rohstoffentnahme und andere natürliche Ressourcen behandelt. In einem "Spezial" wird abschließend die Rohstoffnutzung der Zukunft betrachtet. Quelle: www.umweltbundesamt.de
Les policiers et policières noir-e-s d'origine haïtienne : étude exploratoire sur leurs pratiques de travail.
Creators: name: Benoit, Ernst.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: History, Black.

description: Dans cette recherche, nous chercherons comment l'experience de travail des policiers d'origine haitienne est affecte par une situation minoritaire et empreinte de racisme. Pour ce faire, nous avons tout d'abord mis en evidence l'existence du "racisme" dans la police pour ensuite tenter d'en reperer les effets sur les policiers haitiens a travers leur perception de carriere et leur relations de travail. De l'analyse des donnees (entrevues avec 8 policiers et policieres), est ressortie l'importance de prendre en compte non seulement leur situation minoritaire et le racisme, mais egalement leur positionnement en tant qu'acteurs sociaux qui participent a leur integration. Cette integration a mis en evidence plusieurs pratiques sociales qui ont marque d'une maniere indelebile la societe haitenne, et, par voie de consequence, la communaute haitienne a Montreal. Nous faisons ici reference aux croyances vaudouesques et l'ideologie coloriste qui traverse la culture de ces derniers depuis pres de deux siecles, et posent de nouveaux defits a l'approche communautaire de la police.
Spectral and rotational properties of radio pulsars
Creators: name: Jankowski, Fabian Tobias
Publisher: name: Swinburne
Year: 2024

description: This thesis focusses on radio pulsars, rapidly rotating and highly magnetised neutron stars that emit electromagnetic radiation from their magnetic poles. Large-scale observational projects were performed to improve our understanding of the fundamental physics of these unique objects. An extensive survey of 441 pulsars, the largest to date, was conducted to characterise their radio emission, identifying many that show unusual spectral behaviour. In another programme, the rotation of over 400 pulsars was measured precisely for up to 3 years, resulting in updated models for 205, measurements of their motions in the sky and the discoveries of several sudden spin-up events.
A qualitative study to explore the attitudes of women and obstetricians towards caesarean delivery in rural Bangladesh
Creators: name: Begum, Tahmina
name: Ellis, Cathryn
name: Sarker, Malabika
name: Rostoker, Jean-Francois
name: Rahman, Aminur
name: Anwar, Iqbal
name: Reichenbach, Laura
Publisher: name: BioMed Central
Year: 2018

description: Background: Caesarean section is a lifesaving surgical intervention for women and their newborns, though overutilization is a public health concern. The caesarean rate in Bangladesh is approximately 23% overall, and in private facilities it is over 70%. It is essential to know both the supply side (obstetricians) and demand side (parturient women) views on caesarean birth in order to formulate specific interventions to address the escalating rate of caesareans. Methods: This qualitative study took place in Matlab, a rural sub-district in Bangladesh. We interviewed women attending their 3rd antenatal visit, those with recent caesareans, and obstetricians from both public and private health facilities. In total there were twenty in-depth interviews and four focus group discussions. Study participants were asked about their preferences on birthing mode and knowledge of the caesarean section process. Thematic data analysis was done following a deductive approach. Results: Women from this rural community had a strong preference for normal vaginal birth. However, they were willing to accept the attending health care provider’s decision for caesarean birth. Antenatal care sessions did not provide information on the medical indications for caesarean section. Furthermore, some women had the misconception that episiotomy itself is a ‘small caesarean.’ Primary health care providers and clinic agents (brokers) had a strong influence on women’s decision to choose a health facility for giving birth. However, obstetricians, having a preference for caesarean section, were receiving more patients from these brokers which may be an important reason for the high rate of clinically non-indicated caesareans at private hospitals in Bangladesh. Improper labour monitoring and inadequate staffing at health facilities were additional influences on the preference for caesarean section. However, critical knowledge gaps were also observed among study obstetricians, particularly with regards to the indications for and timing of elective caesarean sections. Conclusion: There is a need to educate women about the advantages and disadvantages of different birthing modes to ensure their active participation in the decision making process. Strong policy regulations are needed to ensure legitimate decision making by obstetricians regarding mode of birthing.
title: PARAGANGLIOMAS CRÁNEO-CERVICALES: Diagnóstico por la imagen y embolización percutánea.
Creators: name: Marin Canete, Antonio
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Diagnostic procedure
subject: Embolisation
subject: Catheter arteriography
subject: CT
subject: MR
subject: Head and neck
subject: Interventional vascular
subject: Vascular

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Realizamos un estudio retrospectivo de los paragangliomas,
especialmente cráneo-cervicales,
diagnosticados en nuestro centro en los últimos 10 años,
así como valoración de la eficacia del tratamiento prequirúrgico con embolización...
EXPLORE: A Novel Method for Local Explanations
Creators: name: Heinrich, Bernd
name: Krapf, Thomas
name: Miethaner, Paul
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: Explainable artificial intelligence, XAI, local explanation, sensitivity
subject: 004 Informatik
subject: 330 Wirtschaft

description: Artificial Intelligence (AI) and especially Machine Learning (ML) models are ubiquitous in research, business and society. However, the predictions of many ML models are often not transparent for users due to their black box nature. Therefore, several Explainable AI (XAI) methods aiming to provide local explanations for individual ML model predictions have been proposed. Importantly, existing XAI methods relying on surrogate models still have critical weaknesses regarding fidelity, robustness and sensitivity. Thus, we propose a novel method that avoids building surrogate models but instead represents the actual decision boundaries and class subspaces of ML models in a functional and definite manner. Further, we introduce two well-founded measures for the sensitivity of individual data instances regarding changes of their features values. We theoretically and empirically evaluate the fidelity and robustness of our method (on three real-world datasets) outperforming existing methods and demonstrate the validity and meaningfulness of our sensitivity measures.
Differences in procedural knowledge after a “spaced” and a “massed” version of an intensive course in emergency medicine, investigating a very short spacing interval
Creators: name: Breckwoldt, Jan
name: Ludwig, Jan R.
name: Plener, Joachim
name: Schroeder, Torsten
name: Gruber, Hans
name: Peters, Harm
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Curriculum planning
subject: Massed learning
subject: Medical education
subject: Spaced learning
subject: Spacing effect
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Distributing a fixed amount of teaching hours over a longer time period (spaced approach) may result in better learning than delivering the same amount of teaching within a shorter time (massed approach). While a spaced approach may provide more opportunities to elaborate the learning content, a massed approach allows for more economical utilisation of teaching facilities and to optimise time resources of faculty. Favourable effects of spacing have been demonstrated for postgraduate surgery training and for spacing intervals of weeks to months. It is however unknown, whether a spacing effect can also be observed for shorter intervals and in undergraduate medical education. Therefore, we aimed to evaluate the effect of a short spacing intervention within an undergraduate intensive course in emergency medicine (EM) on students’ procedural knowledge. Methods An EM intensive course of 26 teaching hours was delivered over either 4.5 days, or 3.0 days. After the course students’ procedural knowledge was assessed by a specifically developed video-case based key-feature test (KF-test). Results Data sets of 156 students (81.7 %, 191 students eligible) were analysed, 54 from the spaced, and 102 from the massed version. In the KF-test students from the spaced version reached a mean of 14.8 (SD 2.0) out of 22 points, compared to 13.7 (SD 2.0) in the massed version (p = .002). Effect size was moderate (Cohen’s d: 0.558). Conclusion A significant spacing effect was observable even for a short spacing interval in undergraduate medical education. This effect was only moderate and may be weighed against planning needs of faculty and teaching resources.
Analyse constructiviste de la naissance du problème de décrochage scolaire au Québec : les discours institutionnels.
Creators: name: Carter, Sandra.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Education, History of.

description: Le decrochage scolaire est aujourd'hui une preoccupation sociale importante contre laquelle des mobilisations autant politiques que sociales sont entreprises. Les conjonctures socio-economiques et politiques des annees soixante ont eu une incidence particuliere sur le systeme d'education. Depuis lors, nous avons assiste a la montee de discours institutionnels sur l'education qui ont de plus en plus attire l'attention des experts, des politiciens, des professionnels. Alors que ces discours sont venus preciser un curriculum academique comportant des etapes particulieres auxquelles les jeunes quebecois doivent se soumettre, le systeme d'education est devenu la cible de tout un mecanisme de surveillance, autant externe qu'interne. Un systeme normatif ou de "penologie" scolaire est alors ne: reglements, sanctions, penalisations, "individualisation" du probleme identifie et marginalisation des non-conformistes. Ce processus de creation d'une nouvelle cible de regulation sociale est l'object de notre analyse. (Abstract shortened by UMI.)
title: Doctor, !me duele la planta del pie!
Creators: name: Madrid Muñiz, Carmen
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Musculoskeletal bone
subject: Musculoskeletal soft tissue
subject: Musculoskeletal system

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir los hallazgos radiológicos que en las distintas modalidades de imagen (radiología convencional,
ultrasonidos,
tomografía computarizada y sobre todo en resonancia magnética) presentan una serie de patologías cuyo síntoma común de...
title: Beyond Pressure Gradients
title: The Effects of Intervention on Heart Power in Aortic Coarctation
titleType: Subtitle
Creators: name: Fernandes, Joao Filipe
name: Goubergrits, Leonid
name: Bruening, Jan
name: Hellmeier, Florian
name: Nordmeyer, Sarah
name: Da Silva, Tiago Ferreira
name: Schubert, Stephan
name: Berger, Felix
name: Kuehne, Titus
name: Kelm, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background In aortic coarctation, current guidelines recommend reducing pressure gradients that exceed given thresholds. From a physiological standpoint this should ideally improve the energy expenditure of the heart and thus prevent long term organ damage. Objectives The aim was to assess the effects of interventional treatment on external and internal heart power (EHP, IHP) in patients with aortic coarctation and to explore the correlation of these parameters to pressure gradients obtained from heart catheterization. Methods In a collective of 52 patients with aortic coarctation 25 patients received stenting and/or balloon angioplasty, and 20 patients underwent MRI before and after an interventional treatment procedure. EHP and IHP were computed based on catheterization and MRI measurements. Along with the power efficiency these were combined in a cardiac energy profile. Results By intervention, the catheter gradient was significantly reduced from 21.8±9.4 to 6.2±6.1mmHg (p<0.001). IHP was significantly reduced after intervention, from 8.03±5.2 to 4.37±2.13W (p < 0.001). EHP was 1.1±0.3 W before and 1.0±0.3W after intervention, p = 0.044. In patients initially presenting with IHP above 5W intervention resulted in a significant reduction in IHP from 10.99±4.74 W to 4.94±2.45W (p<0.001), and a subsequent increase in power efficiency from 14 to 26% (p = 0.005). No significant changes in IHP, EHP or power efficiency were observed in patients initially presenting with IHP < 5W. Conclusion It was demonstrated that interventional treatment of coarctation resulted in a decrease in IHP. Pressure gradients, as the most widespread clinical parameters in coarctation, did not show any correlation to changes in EHP or IHP. This raises the question of whether they should be the main focus in coarctation interventions. Only patients with high IHP of above 5W showed improvement in IHP and power efficiency after the treatment procedure. Trial Registration clinicaltrials.gov NCT02591940
title: Nuevas aportaciones en el diagnóstico por imagen de la carcinomatosis leptomeníngea
Creators: name: Medina Díaz, Montserrat
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: Oncology
subject: MR
subject: Contrast agent-intravenous
subject: Diagnostic procedure
subject: Imaging sequences
subject: Metastases
subject: Cerebrospinal fluid

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar la literatura reciente y describir los signos radiológicos en RM de la carcinomatosis leptomeníngeamediante estudios realizados en nuestro...
Las implicaciones jurídicas en las sociedades de vida apostólica que asumen los consejos evangélicos.
Creators: name: Luna Barrera, Luis Antonio.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Law.

description: Introduction. Parmi les nouveautes que presente le nouveau CIC de 1983, il y a une nouveaute qui touche la vie consacree et les societes de vie apostolique, reservant a celles-ci une section a part, ce qui donne l'impression de faire une separation totale au niveau juridique. Le probleme. Le canon 731 presente apparemment deux groupes differents de societes de vie apostolique: celles qui n'assument pas les conseils evangeliques (§ 1) et celles qui les assument (§ 2). Il y a certains travaux qui ont ete realises et qui concluent que les SVA (§ 1) prennent place aux cotes (accedunt) des Instituts de vie consacree a cause de leur structure et non de leur nature. Notre probleme surgit a partir du § 2 qui exige que certaines SVA assument les conseils evangeliques par un lien defini dans leurs constitutions: nous nous demandons, comment cette affirmation contraint ces SVA a assumer les obligations qui appartiennent aux IVC? Font-elles partie completement du genus de la vie consacree? Doivent-elles vivre et assumer les obligations des conseils evangeliques? Nous pensons que les exigences des conseils evangeliques par un lien sacre peuvent changer d'une certaine maniere la nature des SVA les transformant en IVC. Nous avons cherche a verifier dans les constitutions de certaines SVA le lieu qu' occupent les conseils evangeliques, afin de comprendre l'avenir qu'on leur reserve par rapport au dynamisme de l'Eglise. Nous croyons qu'il existe un vaste terrain pour essayer de clarifier les problemes en cause. Notre travail cherche a jeter un peu de lumiere sur ce sujet delicat. Nous avons intitule notre these: Les implications juridiques dans les societes de vie apostolique qui assument les conseils evangeliques. Methode. Nous avons utilise la methode historico-analytique ainsi qu'une approche personnelle. Nous avons divise le sujet en quatre chapitres: dans le chapitre I, nous avons vu l'origine historique des SVA et leur place dans la vie de l'Eglise; dans le chapitre II, nous avons vu le developpement juridique des conseils evangeliques; dans le chapitre III, nous avons vu les liens sacres en rapport avec le canon 731; dans le chapitre IV, nous avons applique le canon 731 aux constitutions de certaines SVA, nous avons trace une perspective du futur et finalement nous avons termine par une conclusion generale.
title: Paracellular Transport through Healthy and Cystic Fibrosis Bronchial Epithelial Cell Lines
title: Do We Have a Proper Model?
titleType: Subtitle
Creators: name: Molenda, Natalia
name: Urbanova, Katarina
name: Weiser, Nelly
name: Kusche-Vihrog, Kristina
name: Günzel, Dorothee
name: Schillers, Hermann
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: It has been reported recently that the cystic fibrosis transmembrane conductance regulator (CFTR) besides transcellular chloride transport, also controls the paracellular permeability of bronchial epithelium. The aim of this study was to test whether overexpressing wtCFTR solely regulates paracellular permeability of cell monolayers. To answer this question we used a CFBE41o– cell line transfected with wtCFTR or mutant F508del-CFTR and compered them with parental line and healthy 16HBE14o– cells. Transepithelial electrical resistance (TER) and paracellular fluorescein flux were measured under control and CFTR-stimulating conditions. CFTR stimulation significant decreased TER in 16HBE14o– and also in CFBE41o– cells transfected with wtCFTR. In contrast, TER increased upon stimulation in CFBE41o– cells and CFBE41o– cells transfected with F508del-CFTR. Under non-stimulated conditions, all four cell lines had similar paracellular fluorescein flux. Stimulation increased only the paracellular permeability of the 16HBE14o– cell monolayers. We observed that 16HBE14o– cells were significantly smaller and showed a different structure of cell-cell contacts than CFBE41o– and its overexpressing clones. Consequently, 16HBE14o– cells have about 80% more cell-cell contacts through which electrical current and solutes can leak. Also tight junction protein composition is different in ‘healthy’ 16HBE14o– cells compared to ‘cystic fibrosis’ CFBE41o– cells. We found that claudin-3 expression was considerably stronger in 16HBE14o– cells than in the three CFBE41o– cell clones and thus independent of the presence of functional CFTR. Together, CFBE41o– cell line transfection with wtCFTR modifies transcellular conductance, but not the paracellular permeability. We conclude that CFTR overexpression is not sufficient to fully reconstitute transport in CF bronchial epithelium. Hence, it is not recommended to use those cell lines to study CFTR-dependent epithelial transport.
Studies on the susceptibility of pear trees to pear psylla, Psylla pyricola Foerster (Homoptera: Psyllidae).
Creators: name: Chang, Juan F. F.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1977
Subjects: subject: Agriculture, Plant Pathology.

description: Development and behaviour of the pear psylla, Psylla pyricola Foerster, were observed under field and laboratory conditions. Bioassay chambers were used in the laboratory to determine the susceptibility of different taxa of pear to pear psylla attack. The selected plant material and the insects were collected from the field, at the Jordan Experimental Farm, Jordan Station, Ontario. Psylla behaviour in the chambers was compared to field observations and in both cases most adult pear psylla migrated to the leaves of pear by early evening. Pear psylla tested on different plant species and different cultivars of pear did not show significant differences in the relative number of insects per plant species or cultivar. Psylla produced frass in a consistent and reproducible manner on the different taxa tested. Frass deposition was also accompanied by egg laying in the majority of cases. Results indicate that pear psylla fed differentially on the different plants tested. Pear psylla development in the field after 21 days was also observed and the data recorded from it paralleled the data obtained for the same plants tested under bioassay conditions in the laboratory. A cursory analysis of lipid and polar soluble phenolic compounds was performed. The ratio of the common number over the total number of different polar phenolics between the two taxa compared shows a grouping trend among the taxa tested, which is similar to the results from the bioassays and the field study. According to the results obtained in the field, in bioassays, and two-dimensional chromatography of phenolic compounds in the plants tested, these plants can be arranged in three categories: (1) most preferred hosts for Psylla pyricola (Bosc and Old Home), (2) intermediate hosts (Bartlett, Kieffer, and d'Anjou), and (3) least preferred hosts (Clapp, P. ussuriensis, and quince). The present work indicates that pear psylla, tested on the Niagara Peninsula, is a specific pest of the pear crop, but it could feed on quince under unfavorable conditions. The analysis of phenolic compounds indicates that there is definite number of phenolic compounds associated with the susceptibility of the plant successfully attacked by Psylla pyricola .
Determinants of exposure to acrylamide in European children and adults based on urinary biomarkers: results from the "European Human Biomonitoring Initiative" HBM4EU participating studies
Creators: name: Fernández, Sandra
name: Poteser, Michael
name: Kolossa-Gehring, Marike
name: Govarts, Eva
name: Murawski, Aline
name: Rüther, Maria
name: Schmidt, Phillipp
name: Vogel, Nina
name: Weber, Till
Publisher: name: My University
Year: 2023

description: Little is known about exposure determinants of acrylamide (AA), a genotoxic food-processing contaminant, in Europe. We assessed determinants of AA exposure, measured by urinary mercapturic acids of AA (AAMA) and glycidamide (GAMA), its main metabolite, in 3157 children/adolescents and 1297 adults in the European Human Biomonitoring Initiative. Harmonized individual-level questionnaires data and quality assured measurements of AAMA and GAMA (urine collection: 2014-2021), the short-term validated biomarkers of AA exposure, were obtained from four studies (Italy, France, Germany, and Norway) in children/adolescents (age range: 3-18 years) and six studies (Portugal, Spain, France, Germany, Luxembourg, and Iceland) in adults (age range: 20-45 years). Multivariable-adjusted pooled quantile regressions were employed to assess median differences ((beta) coefficients) with 95% confidence intervals (95% CI) in AAMA and GAMA ((micro)g/g creatinine) in relation to exposure determinants. Southern European studies had higher AAMA than Northern studies. In children/adolescents, we observed significant lower AA associated with high socioeconomic status (AAMA: (beta) = -9.1 (micro)g/g creatinine, 95% CI -15.8, -2.4; GAMA: (beta) = -3.4 (micro)g/g creatinine, 95% CI-4.7, - 2.2), living in rural areas (AAMA: (beta) = - 4.7 (micro)g/g creatinine, 95% CI - 8.6, - 0.8; GAMA: (beta) = - 1.1 (micro)g/g creatinine, 95% CI -1.9, -0.4) and increasing age (AAMA: (beta)= -1.9 (micro)g/g creatinine, 95% CI -2.4, -1.4; GAMA: (beta) = -0.7 (micro)g/g creatinine, 95% CI -0.8, -0.6). In adults, higher AAMA was also associated with high consumption of fried potatoes whereas lower AAMA was associated with higher body-mass-index. Based on this large-scale study, several potential determinants of AA exposure were identified in children/adolescents and adults in European countries. © The Author(s) 2023
Investigation of packet loss reduction methods and decentralization for dynamic routing in packet-switching networks.
Creators: name: Lamontagne, Luc D.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, System Science.

description: In this thesis, we slightly modify a known routing model in packet-switching networks. Those modifications give priority to messages transiting in the network (internal) over external arrivals (users) incoming to each node while reducing the number of lost packets. Mathematical programs are developed for the multiple and single buffer node models. Those take into account line capacities, finite buffers and channel errors during transmission. We investigate a simple decentralized routing policy, based on the proposed centralized model with multiple buffers, where partial information is available from neighboring nodes only. Integer linear programming is used to optimally solve the routing problem for each of the models studied. Simulation, conducted on a 5-node network, illustrates the impact of these modifications.
Asthma
Creators: name: Quirt, Jaclyn
name: Hildebrand, Kyla J.
name: Mazza, Jorge
name: Noya, Francisco
name: Kim, Harold
Publisher: name: BioMed Central
Year: 2018

description: Asthma is the most common respiratory disorder in Canada. Despite significant improvement in the diagnosis and management of this disorder, the majority of Canadians with asthma remain poorly controlled. In most patients, however, control can be achieved through the use of avoidance measures and appropriate pharmacological interventions. Inhaled corticosteroids (ICS) represent the standard of care for the majority of patients. Combination ICS/long-acting beta2-agonist inhalers are preferred for most adults who fail to achieve control with ICS therapy. Biologic therapies targeting immunoglobulin E or interleukin-5 are recent additions to the asthma treatment armamentarium and may be useful in select cases of difficult to control asthma. Allergen-specific immunotherapy represents a potentially disease-modifying therapy for many patients with asthma, but should only be prescribed by physicians with appropriate training in allergy. In addition to avoidance measures and pharmacotherapy, essential components of asthma management include: regular monitoring of asthma control using objective testing measures such as spirometry, whenever feasible; creation of written asthma action plans; assessing barriers to treatment and adherence to therapy; and reviewing inhaler device technique. This article provides a review of current literature and guidelines for the appropriate diagnosis and management of asthma in adults and children.
Impacts of mandatory international financial reporting standards adoption on foreign shareholdings of public listed companies in Malaysia
Creators: name: Shovon, Muhammed Kamrul Hasan
Publisher: name: Swinburne
Year: 2024

description: This research examines the direct effects of IFRS adoption on foreign shareholdings and tests intervening effects of investor protection, stock market development, and auditor quality on the relationship. Results suggest that IFRS adoption had no significatn positive effect on foreign shareholdings in Malaysia. Also, investor protection failed to moderate the relationship between IFRS adoption and foreign shareholdings. However, stock market development and auditor quality have positive and negative moderating effects respectively in the relationship between IFRS adoption and foreign shareholding. Hence, Malaysian government should increase investor protection and stock market development in order to attract foreign capital through IFRS adoption.