cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2 of Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models
Creators: name: Margotta, Cassandra
name: Fabbrizio, Paola
name: Ceccanti, Marco
name: Cambieri, Chiara
name: Ruffolo, Gabriele
name: D’Agostino, Jessica
name: Trolese, Maria Chiara
name: Cifelli, Pierangelo
name: Alfano, Veronica
name: Laurini, Christian
name: Scaricamazza, Silvia
name: Ferri, Alberto
name: Sorarù, Gianni
name: Palma, Eleonora
name: Inghilleri, Maurizio
name: Bendotti, Caterina
name: Nardo, Giovanni
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Original full-length blot images for Figs. 3A, 5A, 7D and 8A-D.
Optogenetic Inhibition of the mPFC During Delay Discounting
Creators: name: White, Shelby M
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Cognitive neuroscience
Psychophysiology
Decision making

description: Impulsivity, or the tendency to act prematurely without foresight, has been linked to a diverse range of pathological conditions. Foresight refers to the ability to envision future rewards and events (i.e. prospectively sample) and has been associated with decreased impulsivity. One form of impulsivity is measured by the ability to delay gratification and is often studied in the framework of Delay Discounting (DD). DD provides the means to study impulsivity in a number of pathological conditions. However, whether impulsivity precedes the development of pathological states or results from the pathological state itself is not fully understood. This necessitates an understanding of neurobiological mechanisms contributing to decision making in both non-impulsive as well as impulsive populations of individuals. Animal models allow invasive techniques to be used to dissect the neurocircuitry involved in decision making. Given that the decision-making process is an ongoing process rather than an isolated event, optogenetics provide the temporal and spatial specificity necessary for evaluating brain region specific contributions to decision making in DD. In the present study, optogenetics were used to assess the contribution of the medial Prefrontal Cortex (mPFC), a brain region involved in ‘goal-directed’ behavior, in the planning of future choices (i.e. prospective plans) and subsequent measures of impulsivity in an adjusting amount DD procedure. Optogenetic inhibition of mPFC was conducted in Wistar rats during different epochs of a DD task in order to assess how mPFC affects planning behavior in a population of rat not considered to be highly impulsive. Although no direct effects on planning behavior (e.g. consistency) were observed, inhibiting mPFC after a trial has been initiated and directly before a choice was made (Epoch 2) was observed to increase measures of impulsivity in comparison to days where no optogenetic manipulation occurred in a delay-specific manner. This suggests that mPFC differentially contributes to decision making at different delays. A pattern of associations between choice latency, impulsivity, and consistency began to emerge for inactivation occurring in Epoch 2, suggesting that mPFC contributes to some aspect of planning choices during this epoch. Moreover, these results indicate that mPFC is involved in decision making in Wistar Rats. Understanding the direct role that mPFC plays in promoting choices of delayed rewards provides a neurobiological target for treatment aimed at reducing impulsivity in the clinical population.
Additional file 1 of Social skills in neurodevelopmental disorders: a study using role-plays to assess adolescents and young adults with 22q11.2 deletion syndrome and autism spectrum disorders
Creators: name: Feller, Clémence
name: Ilen, Laura
name: Eliez, Stephan
name: Schneider, Maude
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1.
PEDESTRIAN-VEHICLE INTERACTIONS AT SEMI-CONTROLLED CROSSWALKS: EXPLANATORY METRICS AND MODELS
Creators: name: Zhang, Yunchang
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Civil engineering not elsewhere classified

description: A large number of crosswalks are indicated by pavement markings and signs but are not signal-controlled. In this study, such a location is called “semi-controlled”. In locations where such a crosswalk has moderate amounts of pedestrian and vehicle traffic, pedestrians and motorists often engage in a non-verbal “negotiation”, to determine who should proceed first. In this study, 3400 pedestrian-motorist non-verbal interactions at such semi-controlled crosswalks were recorded by video. The crosswalk locations observed during the study underwent a conversion from one-way operation in Spring 2017 to two-way operation in Spring 2018. This offered a rare opportunity to collect and analyze data for the same location under two conditions. This research explored factors that could be associated with pedestrian crossing behavior and motorist likelihood of decelerating. A mixed effects logit model and binary logistic regression were utilized to identify factors that influence the likelihood of pedestrian crossing under specific conditions. The complementary motorist models used generalized ordered logistic regression to identify factors that impact a driver’s likelihood of decelerating, which was found to be a more useful factor than likelihood of yielding to pedestrian. The data showed that 56.5% of drivers slowed down or stopped for pedestrians on the one-way street. This value rose to 63.9% on the same street after it had been converted to 2-way operation. Moreover, two-way operation eliminated the effects of the presence of other vehicles on driver behavior. Also investigated were factors that could influence how long a pedestrian is likely to wait at such semi-controlled crosswalks. Two types of models were proposed to correlate pedestrian waiting time with various covariates. First, survival models were developed to analyze pedestrian wait time based on the first-event analysis. Second, multi-state Markov models were introduced to correlate the dynamic process between recurrent events. Combining the first-event and recurrent events analyses addressed the drawbacks of both methods. Findings from the before-and-after study can contribute to developing operational and control strategies to improve the level of service at such unsignalized crosswalks. The results of this study can contribute to policies and/or control strategies that will improve the efficiency of semi-controlled and similar crosswalks. This type of crosswalk is common, so the benefits of well-supported strategies could be substantial.
Proteomic analysis of protein carbonylation: a useful tool to unravel nanoparticle toxicity mechanisms
Creators: name: Driessen, Marc D.
name: Mues, Sarah
name: Vennemann, Antje
name: Hellack, Bryan
name: Bannuscher, Anne
name: Vimalakanthan, Vishalini
name: Riebeling, Christian
name: Ossig, Rainer
name: Wiemann, Martin
name: Schnekenburger, Jürgen
name: Kuhlbusch, Thomas A. J.
name: Renard, Bernhard Y.
name: Luch, Andreas
name: Haase, Andrea
Publisher: name: Robert Koch-Institut
Year: 2015
Subjects: subject: Surface functionalization
subject: Protein carbonylation
subject: Oxidative stress
subject: Silica nanoparticles
subject: Zirconium oxide nanoparticles
subject: Silver nanoparticles
subject: Rat lung
subject: ESR
subject: DCFDA
subject: 610 Medizin

description: Background: Oxidative stress, a commonly used paradigm to explain nanoparticle (NP)-induced toxicity, results from an imbalance between reactive oxygen species (ROS) generation and detoxification. As one consequence, protein carbonyl levels may become enhanced. Thus, the qualitative and quantitative description of protein carbonylation may be used to characterize how biological systems respond to oxidative stress induced by NPs. Methods: We investigated a representative panel of 24 NPs including functionalized amorphous silica (6), zirconium dioxide (4), silver (4), titanium dioxide (3), zinc oxide (2), multiwalled carbon nanotubes (3), barium sulfate and boehmite. Surface reactivities of all NPs were studied in a cell-free system by electron spin resonance (ESR). NRK-52E cells were treated with all NPs, analyzed for viability (WST-1 assay) and intracellular ROS production (DCFDA assay). Carbonylated proteins were assessed by 1D and/or 2D immunoblotting and identified by matrix assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF/TOF). In parallel, tissue homogenates from rat lungs intratracheally instilled with silver NPs were studied. Results: Eleven NPs induced elevated levels of carbonylated proteins. This was in good agreement with the surface reactivity of the NPs as obtained by ESR and the reduction in cell viability as assessed by WST-1 assay. By contrast, results obtained by DCFDA assay were deviating. Each NP induced an individual pattern of protein carbonyls on 2D immunoblots. Affected proteins comprised cytoskeletal components, proteins being involved in stress response, or cytoplasmic enzymes of central metabolic pathways such as glycolysis and gluconeogenesis. Furthermore, induction of carbonyls upon silver NP treatment was also verified in rat lung tissue homogenates. Conclusions: Analysis of protein carbonylation is a versatile and sensitive method to describe NP-induced oxidative stress and, therefore, can be used to identify NPs of concern. Furthermore, detailed information about compromised proteins may aid in classifying NPs according to their mode of action.
MAKING CROSSWALKS SMARTER: USING SENSORS AND LEARNING ALGORITHMS TO SAFEGUARD HETEROGENEOUS ROAD USERS
Creators: name: Zhang, Yunchang
Publisher: name: Purdue University Graduate School
Year: 2022
Subjects: Civil engineering not elsewhere classified

description: The research described in this dissertation began in response to frequent questions from users of several crosswalks near a university campus. At each crosswalk was a sign indicating that motorists should yield to pedestrians in the crosswalk. That this message was not being interpreted uniformly was a concern at locations where heterogeneous road users (pedestrians, cyclists, and motorists) were interacting. Instead of trying to impose a single interpretation on users of each crosswalk, it was decided to observe and analyze interactions between users of the crosswalk. Several hours of video were recorded of pedestrians and motorists “negotiating” the right of way at the crosswalk. Because these crossing locations were marked but not signalized, they were called “semi-controlled crosswalks”. The negotiations took place during what were called pedestrian-motorist interactions (PMIs). The PMIs observed on video can be characterized as a “zebra-crossing” game, as described in Chapter 4 of this dissertation. Recently, computer vision (CV) algorithms have been extensively used in road users’ detection and tracking at an unparalleled spatial-temporal scale. In this study, CV algorithms have been applied to convert the video recordings into a large-scale spatial-temporal trajectory dataset including 800 pedestrians and cyclists interacting with more than 500 vehicles. Utilizing the trajectory dataset, a spatial-temporal graph convolutional network-based sequence to sequence (ST-GCN-Seq2Seq) algorithm has been developed to reasonably forecast heterogeneous road users’ trajectories and behavior in real time. Combining CV and ST-GCN-Seq2Seq algorithms can help both design an intelligent tracking system and achieve a form of “smart” interaction at semi-controlled crosswalks for heterogeneous road users. Based on road users’ arrival patterns detected from CV algorithms, it is likely that a "smart" control strategy can minimize the delay of pedestrians and motorists at crosswalks. Therefore, another branch of this study is to investigate the “smart” control strategies at crosswalks using traffic signal controllers. A reinforcement learning framework was proposed as the “smart” control strategy, and several experiments were conducted using microsimulation. The proposed reinforcement learning framework is able to reduce traffic delay (efficiency), considering real-time pedestrian flow rates and vehicle flow rates with appropriate sensors.
Supplemental Material, sj-pdf-3-tva-10.1177_15248380211029398 - Understanding the Components and Determinants of Police Attitudes Toward Intervention in Intimate Partner Violence Against Women: A Systematic Review
Creators: name: Serrano-Montilla, Celia
name: Lozano, Luis M.
name: Alonso-Ferres, María
name: Valor-Segura, Inmaculada
name: Padilla, Jose-Luis
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, sj-pdf-3-tva-10.1177_15248380211029398 for Understanding the Components and Determinants of Police Attitudes Toward Intervention in Intimate Partner Violence Against Women: A Systematic Review by Celia Serrano-Montilla, Luis M. Lozano, María Alonso-Ferres, Inmaculada Valor-Segura and Jose-Luis Padilla in Trauma, Violence, & Abuse
ORENITRAM’s decadal journey: unveiling safety profiles and adverse event through a real-world pharmacovigilance study of FAERS events
Creators: name: Chai, Shengjun
name: Xu, Haiming
name: Xu, Guocai
name: Cai, Chunmei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Mental Health

description: ORENITRAM, an oral treprostinil formulation, was approved in 2013 for pulmonary arterial hypertension (PAH) treatment, necessitating ongoing safety monitoring. This retrospective analysis used FDA Adverse Event Reporting System data from Q4 2013 to Q4 2023, employing disproportionality analysis and the reporting odds ratio (ROR) to identify adverse events (AEs) linked with ORENITRAM. Out of 15,660,695 reports, ORENITRAM was the primary suspect in 10,125 cases. We identified 174 significant adverse events across 27 organ systems, with notable issues like pulmonary edema, ascites, and ventricular fibrillation. Females reported more AEs (75.6%) than males (24.0%), suggesting potential metabolic differences. AEs were most common within 30 days of starting treatment or after one year. The study indicates significant safety issues with ORENITRAM, including serious unexpected events such as pulmonary edema, ascites, and ventricular fibrillation. These findings highlight the necessity for careful clinical monitoring and effective risk management, particularly with observed gender differences in AE profiles. The study’s retrospective nature and reliance on spontaneous reports may affect result generalizability.
"The Roots of Anti-Asian Racism in the U.S.: The Pandemic and ‘Yellow Peril’." Global Social Security Review Vol. 15 (Winter 2020): 50-59
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Critical race theory
subject: Asian Americans--Study and teaching

description: Scroll down to read the Korean, followed by English, versions  ::::::      COVID-19 has exacerbated anti-Asian racism—the demonization of a group of people based on their perceived social value—in the United States in the cultural and political life. Offering strategies for inclusion during and after the pandemic, this article analyzes the history and language of racism, including the notion of yellow peril. Racialized thinking and racial discourses are institutionalized as power relations, take the form of political marginalization of minority groups, and cause emotional distress and physical harm.  COVID-19로 인해 미국에서는 사람들이 인식하는 사회적 가치를 기반으로 특정 집단을 악마화하는 반아시아인종주의가 문화와 정치적 삶에서 심화되고 있다. 본 내용은 코로나 팬데믹 기간 동안 그리고 그 이후 포용에 대한 전략을 제시하고 황화(yellow peril)에 대한 개념 등 인종차별주의의 역사와 언어를 분석한다. 인종차별적사고와 인종 담론은 권력 관계로서 자리를 잡게 되고 소수집단을 정치적 비주류로 만들며 정서적 고통과 신체적피해를 유발한다. ::::::  Published by the Korean Institute for Health and Social Affairs
Hepatitis E Virus Superinfection and Clinical Progression in Hepatitis B Patients
Creators: name: Hoan, Nghiem Xuan
name: Tong, Hoang Van
name: Hecht, Nicole
name: Sy, Bui Tien
name: Marcinek, Patrick
name: Meyer, Christian G.
name: Song, Le Huu
name: Toan, Nguyen Linh
name: Kurreck, Jens
name: Kremsner, Peter G.
name: Bock, Thomas
name: Velavan, Thirumalaisamy P.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2015
Subjects: subject: Humans
subject: Risk Factors
subject: Treatment Outcome
subject: Disease Progression
subject: Antiviral Agents/therapeutic use
subject: Hepacivirus/drug effects
subject: Hepacivirus/immunology
subject: Hepacivirus/pathogenicity
subject: Hepatitis C Chronic/diagnosis
subject: Hepatitis C Chronic/drug therapy
subject: Hepatitis C Chronic/immunology
subject: Hepatitis C Chronic/virology
subject: Immunocompromised Host
subject: Immunosuppressive Agents/adverse effects
subject: Superinfection
subject: 610 Medizin

description: Hepatitis E virus (HEV) infection may cause acute hepatitis and lead to hepatic failure in developing and developed countries. We studied HEV seroprevalences in patients with hepatitis B virus (HBV) infection to understand the consequences of HEV superinfection in a Vietnamese population. This cross-sectional study was conducted from 2012 to 2013 and included 1318 Vietnamese patients with HBV-related liver diseases and 340 healthy controls. The case group included patients with acute (n = 26) and chronic hepatitis B (n = 744), liver cirrhosis (n = 160), hepatocellular carcinoma (n = 166) and patients with both liver cirrhosis and hepatocellular carcinoma (n = 222). Anti-HEV IgG and IgM antibodies were assessed in patients and controls by ELISA. HEV-RNA was identified by PCR assays and sequencing. Seroprevalences of anti-HEV IgG among hepatitis B patients and controls were 45% and 31%, respectively (adjusted P = 0.034). Anti-HEV IgM seroprevalences were 11.6% and 4.7% in patients and controls, respectively (adjusted P = 0.005). Seroprevalences were higher among the elder individuals. When stratifying for patient groups, those with liver cirrhosis had the highest anti-HEV IgG (52%) and anti-HEV IgM (19%) seroprevalences. Hepatitis B patients with current HEV infection had abnormal liver function tests compared to patients with past or without HEV infection. One HEV isolate was retrieved from a patient with both liver cirrhosis and hepatocellular carcinoma and identified as HEV genotype 3. This study indicates high prevalences of HEV infection in Vietnamese HBV patients and among healthy individuals and shows that HEV superinfection may influence the outcome and progression of HBV-related liver disease.
Adverse events associated with tezepelumab: a safety analysis of clinical trials and a pharmacovigilance system
Creators: name: Mao, Zhenyu
name: Huang, Yuchen
name: Zhu, Xiaoyan
name: Zheng, Pengdou
name: Wang, Lingling
name: Zhang, Fengqin
name: Liu, Wei
name: Liu, Huiguo
name: Liao, Wenhui
name: Zhou, Ling
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Tezepelumab is the first asthma biologic approved by the FDA that is not restricted by biomarker phenotypes. To date, there have been no studies reporting adverse events (AEs) associated with the real-world use of tezepelumab. This study included a comprehensive evaluation of AE reports related to tezepelumab since its approval (4th quarter of 2021 to 1st quarter of 2024) using the FAERS database, and compared with the currently reported clinical trial results (ClinicalTrials.gov). A total of 2153 reports of tezepelumab-related AEs were extracted. 256 preferred terms (PTs) of adverse reactions involving 27 system organ classes were identified. Significant AEs that were not reported on the drug label, such as ‘dyspnea,’ ‘body temperature,’ and ‘tongue pruritus,’ were reported. The median time to onset (TTO) of tezepelumab-related AEs was 35 days.The most frequent AEs in different sexes were ‘arthralgia’ and ‘dyspnea,’ with differences in signal strength ranking between the sexes. This study represents the largest report to date on tezepelumab-related AEs, providing valuable insights into the potential side effects of tezepelumab. This work is crucial for the broader clinical application of this novel biologic and improving outcomes for patients with severe asthma.
Baseline participation in a health examination survey of the population 65 years and older: who is missed and why?
Creators: name: Gaertner, Beate
name: Seitz, Ina
name: Fuchs, Judith
name: Busch, Markus
name: Holzhausen, Martin
name: Martus, Peter
name: Scheidt-Nave, Christa
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: Aging population
subject: Non-participation
subject: Public health monitoring
subject: Reasons for non-participation
subject: Register-based population
subject: Selection bias
subject: 610 Medizin

description: Background: Public health monitoring depends on valid health and disability estimates in the population 65+ years. This is hampered by high non-participation rates in this age group. There is limited insight into size and direction of potential baseline selection bias. Methods: We analyzed baseline non-participation in a register-based random sample of 1481 inner-city residents 65+ years, invited to a health examination survey according to demographics available for the entire sample, self-report information as available and reasons for non-participation. One year after recruitment, non-responders were revisited to assess their reasons. Results: Five groups defined by participation status were differentiated: participants (N = 299), persons who had died or moved (N = 173), those who declined participation, but answered a short questionnaire (N = 384), those who declined participation and the short questionnaire (N = 324), and non-responders (N = 301). The results confirm substantial baseline selection bias with significant underrepresentation of persons 85+ years, persons in residential care or from disadvantaged neighborhoods, with lower education, foreign citizenship, or lower health-related quality of life. Finally, reasons for non-participation could be identified for 78 % of all non-participants, including 183 non-responders. Conclusion: A diversity in health problems and barriers to participation exists among non-participants. Innovative study designs are needed for public health monitoring in aging populations.
Additional file 1 of School completion and progression to higher education in adolescents with social anxiety: a linkage between Young-HUNT3 and national educational data (2008–2019), Norway
Creators: name: Jystad, Ingunn
name: Haugan, Tommy
name: Bjerkeset, Ottar
name: Sund, Erik R.
name: Aune, Tore
name: Nordahl, Hans M.
name: Vaag, Jonas R.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Supplementary Material 1
ПРОФИЛАКТИКА ИНСПЕКТОРЛАРИНИНГ ОЗОДЛИКДАН МАҲРУМ ЭТИШ БИЛАН БОҒЛИҚ БЎЛМАГАН ЖАЗОЛАРГА ТОРТИЛГАН ШАХСЛАР БИЛАН ИШЛАШ ФАОЛИЯТИ ТУШУНЧАСИ.
Creators: name: Кушбаков, Дилшод
name: Эгамбердиев, Вохиджон
Publisher: name: Zenodo
Year: 2024

description: Ушбу мақолада профилактика инспекторларининг озодликдан маҳрум этиш билан боғлиқ бўлмаган жазоларга тортилган шахслар билан ишлаш фаолияти, ушбу фаолиятни ташкил этиш тартиби, амалга ошириладиган чора-тадбирлар ҳамда профилактика инспекторларининг озодликдан маҳрум этиш билан боғлиқ бўлмаган жазоларга тортилган шахслар билан ишлашда амалга ошириладиган ҳамкорлик ёритиб берилган.
Health-related behaviour in Europe – A comparison of selected indicators for Germany and the European Union
Creators: name: Lange, Cornelia
name: Finger, Jonas D.
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: PHYSICAL ACTIVITY
subject: OBESITY
subject: DIET
subject: SUBSTANCE USE
subject: EUROPEAN COMPARISON
subject: 610 Medizin

description: Demographic change, new health threats, but also inequalities in health and health care provision in and between European Union (EU) member states pose major albeit similar challenges to European health systems. Regular information on health and health-related behaviour is essential if member states’ health systems are to respond and develop appropriately to these challenges. The ‘European Health Interview Survey’ (EHIS) is a vital source of data for indicators of health status and health-related behaviour in the EU. This article presents a comparative review of health-related behaviour at the European level. Health-related behaviour is of particular relevance because an unhealthy diet, physical inactivity, obesity, smoking, and harmful use of alcohol are among the most important determinants associated with non-communicable chronic diseases. Eurostat has used data from EHIS Wave 2 to publish details about the current prevalence of obesity, daily fruit and vegetable intake, health-enhancing aerobic physical activity, smoking and heavy episodic drinking for the EU’s member states. In the following, the figures for Germany are compared to the European average. A wide range of prevalences exists between the various EU member states, in some cases stretching to more than 50 percentage points. In Germany, the prevalence of obesity and smoking remains relatively close to the EU average. Moreover, the results on physical activity are especially welcome. In particular, the proportion of women and men who undertake adequate levels of physical activity decreases more slowly with increasing age compared to the EU average. Nevertheless, the low fruit and vegetable intake, especially among younger generations, and the high proportion of women and men who drink six or more alcoholic beverages on one occasion (heavy episodic drinking) at least once a month pose problems for Germany. In summary, the results provided by EHIS offer a basis for sharing experiences between EU member states regarding effective measures in health promotion and disease prevention.
Supplementary Material for Paper "Formally Verifying a Behavior Planner: Balancing Efficiency and Precision"
Creators: name: Koenig, Lukas
name: Henze, Franziska
name: Heinzemann, Christian
name: Klauck, Michaela
name: Griggio, Alberto
name: Tonetta, Stefano
name: Cimatti, Alessandro
Publisher: name: Zenodo
Year: 2025

description: Contains the full experimental data accompanying the paper "Formally Verifying a Behavior Planner: Balancing Efficiency and Precision" which has been submitted to the IEEE Transactions on Intelligent Vehicles. Each zip file belongs to one of the main sets of experiments.

To reproduce some of the results, check out our award-winning artifact.

If you want to reproduce all experiments, see the sources or contribute to our research, go to our open source project or contact lukas.koenig@de.bosch.com.
The Way of Conceptual Idea of Citizen Engagement in Mobilizing the Project of Five-Precept Village for Peaceful Community : A Case Study of Bannonedum Community, Kampaengphet Province
Creators: name: Phrakhrusantiwachirakit (Wimok)
name: Phramaha Duangden Thitanano
name: Khanthong Wattanapradith
Publisher: name: Master of Arts Program in Peace Studies, Mahachulalongkornrajavidyalaya University
Year: 2017
Subjects: Citizen Engagement; the Project of Five-Precept Village; Peaceful Community

description: Journal of MCU Peace Studies, 5, sp1
Supplemental Material, sj-pdf-1-het-10.1177_09603271211030558 - Quercetin inhibited the proliferation and invasion of hepatoblastoma cells through facilitating SIRT6-medicated FZD4 silence
Creators: name: Liu, T
name: Li, Z
name: Tian, F
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental Material, sj-pdf-1-het-10.1177_09603271211030558 for Quercetin inhibited the proliferation and invasion of hepatoblastoma cells through facilitating SIRT6-medicated FZD4 silence by T Liu, Z Li and F Tian in Human & Experimental Toxicology
Additional file 1 of QNetDiff: a quantitative measurement of network rewiring
Creators: name: Nose, Shota
name: Shiroma, Hirotsugu
name: Yamada, Takuji
name: Uno, Yushi
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1. Supplementary Materials.
The Model of Carita Application to the Mediation of Mediators in the Court of Justice
Creators: name: Pirapart Wiboonwatthanakit
name: Phramaha Hansa Dhammahaso
name: Khanthong Wattanapradith
Publisher: name: Master of Arts Program in Peace Studies, Mahachulalongkornrajavidyalaya University
Year: 2017
Subjects: The Six Carita; Mediation; Mediators

description: Journal of MCU Peace Studies, 5, sp1
Severe cutaneous adverse reactions due to antibiotics therapy: a pharmacovigilance analysis of FDA adverse event reporting system events
Creators: name: Zhou, Lu
name: Yang, Jing
name: Xiao, Min
name: Shan, HuiFang
name: Liu, MaoZhu
name: Lu, Yun
name: Zou, Ya
name: Wu, Bin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Science Policy

description: The aim of this study was to monitor, identify and evaluate severe cutaneous adverse reactions (SCAR) induced by antibiotics in patients. Disproportionality algorithms were performed in data mining to screen suspected SCAR after using nine categories of antibiotics based on the FDA’s Adverse Event Reporting System (FAERS) from January 2004 to December 2022. The drug information and demographic characteristics of antibiotic-associated SCAR were also investigated. The FAERS database received 12,212 antibiotic-associated SCAR cases. Approximately half of the SCAR patients were females, the majority of them were adults aged 18–65 years (48.35%), and 47.68% of SCAR patients required hospitalization. The highest SCAR signals RORs (95% CI) for antibiotics were: sulfonamides 23.30 (22.05–24.62), glycopeptides 21.27 (20.26–22.33), penicillins 16.00 (15.44–16.59), carbapenems 10.46 (9.57–11.44), and cephalosporins 13.27 (12.57–14.00). Cefotaxime, sulfamethoxazole/trimethoprim, cefixime, vancomycin, piperacillin, ceftriaxone, amoxicillin, and meropenem had stronger associations with the SCAR than the other antibiotics. However, sulfonamides-associated SCAR cases had the lowest fatality rate (6.23%), penicillin-associated SCAR cases had the highest hospitalization rate (54.16%), and carbapenem-associated SCAR cases seemingly resulted in the highest risk of death (19.03%). Data mining of FAERS identified 30 antibiotic-associated SCAR signals, and provided a referable evidence of the occurrence, characteristics and prognosis of antibiotic-related SCARs.
WRIT 1002 V3/V4S (Spring 2021)
Creators: name: Gifford, James
Publisher: name: unknown
Year: 2021
Subjects: subject: Interdisciplinary approach in education
subject: College freshmen
subject: College students' writings
subject: Composition (Language arts)
subject: Academic writing

description: This course provides students with intensive study and practice in process-oriented writing, critical reading, and rhetorical inquiry. Students engage expository texts in order to describe and evaluate the choices writers make and then apply that knowledge to their own compositions. Throughout the course, students give and receive feedback, revise their work, and reflect on their growth as writers.
The Way to apply Peace Dhamma for enchancing peace of the school youth : A Case study of Rajmontri School (Pleume  Chuamnugoon)
Creators: name: Phramaha Prasert Akkatecho
name: Phramaha Duangden Thita?Ano
name: Kanthong Wattanapradith
Publisher: name: Master of Arts Program in Peace Studies, Mahachulalongkornrajavidyalaya University
Year: 2017
Subjects: Application; Principle of Peaceful Dhammas; Peacefulness

description: Journal of MCU Peace Studies, 5, sp1
Additional file 1 of Discrimination of SARS-CoV-2 omicron variant and its lineages by rapid detection of immune-escape mutations in spike protein RBD using asymmetric PCR-based melting curve analysis
Creators: name: Kong, Xiaomu
name: Gao, Peng
name: Jiang, Yongwei
name: Lu, Lixia
name: Zhao, Meimei
name: Liu, Yi
name: Deng, Guoxiong
name: Zhu, Haoyan
name: Cao, Yongtong
name: Ma, Liang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1: Table S1. Insert sequence of plasmids.
Performance role of the Village Committee in Maung Nong Khai District, Nong Khai
Creators: name: Rattiporn Sirisri
name: Sanya Kenaphoom
Publisher: name: Master of Arts Program in Peace Studies, Mahachulalongkornrajavidyalaya University
Year: 2017
Subjects: Performance; Role; the Village Committee

description: Journal of MCU Peace Studies, 5, sp1
A FRAMEWORK TO ASSESS POST-CONFLICT ENVIRONMENT IMPACT ON CONSTRUCTION ORGANIZATION PERFORMANCE
Creators: name: Amarkhil, Qais
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Building construction management and project planning

description: In the field of the construction industry, the research work has been widely focused on identifying key performance indicators and critical success factors without assessing the impact of conflict environment factors. This study focusses on the impact of post-conflict environment factors on local construction organization performance. This research presents a performance prediction model comprising the effect of post-conflict environment factors on construction organization performance. The proposed framework of this study has four stages: identify key performance indicators (KPIs), identify post-conflict environment impacting factors, determine critical success factors (CSFs), and formulate success strategy to improve performance. Analytical hierarchy process (AHP) and multiple linear regression (MLR) techniques are applied to analyze the data. The study finding indicates that there is a significant relationship between the post-conflict condition impacting factors and local construction organization performance, which is insufficiently studied in previous research work. Thus, the developed framework will benefit academic scholars and industry practitioners to analyze and evaluate challenges and opportunities caused by different external environment conditions in the post-conflict construction industry.
sj-docx-1-psp-10.1177_01461672211030383 – Supplemental material for Contrasting Effects of Finding Meaning and Searching for Meaning, and Political Orientation and Religiosity, on Feelings and Behaviors During the COVID-19 Pandemic
Creators: name: Newman, David B.
name: Schneider, Stefan
name: Stone, Arthur A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-psp-10.1177_01461672211030383 for Contrasting Effects of Finding Meaning and Searching for Meaning, and Political Orientation and Religiosity, on Feelings and Behaviors During the COVID-19 Pandemic by David B. Newman, Stefan Schneider and Arthur A. Stone in Personality and Social Psychology Bulletin
WRIT 1002 V3/V4S (Spring 2021)
Creators: name: Gifford, James
Publisher: name: Humanities Commons
Year: 2021
Subjects: subject: College students' writings
subject: College freshmen
subject: Composition (Language arts)
subject: Academic writing
subject: Interdisciplinary approach in education

description: This course provides students with intensive study and practice in process-oriented writing, critical reading, and rhetorical inquiry. Students engage expository texts in order to describe and evaluate the choices writers make and then apply that knowledge to their own compositions. Throughout the course, students give and receive feedback, revise their work, and reflect on their growth as writers.
sj-docx-2-psp-10.1177_01461672211030383 – Supplemental material for Contrasting Effects of Finding Meaning and Searching for Meaning, and Political Orientation and Religiosity, on Feelings and Behaviors During the COVID-19 Pandemic
Creators: name: Newman, David B.
name: Schneider, Stefan
name: Stone, Arthur A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-2-psp-10.1177_01461672211030383 for Contrasting Effects of Finding Meaning and Searching for Meaning, and Political Orientation and Religiosity, on Feelings and Behaviors During the COVID-19 Pandemic by David B. Newman, Stefan Schneider and Arthur A. Stone in Personality and Social Psychology Bulletin
Additional file 2 of Discrimination of SARS-CoV-2 omicron variant and its lineages by rapid detection of immune-escape mutations in spike protein RBD using asymmetric PCR-based melting curve analysis
Creators: name: Kong, Xiaomu
name: Gao, Peng
name: Jiang, Yongwei
name: Lu, Lixia
name: Zhao, Meimei
name: Liu, Yi
name: Deng, Guoxiong
name: Zhu, Haoyan
name: Cao, Yongtong
name: Ma, Liang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2: Table S2. Reaction mix composition for the asymmetric PCR melting curve analysis-based method.
The Critical Study of The Concept of The Love and Marriage in Theravada Buddhist Philosophy
Creators: name: Phramaha Khwanchai Kittimethi
Publisher: name: Master of Arts Program in Peace Studies, Mahachulalongkornrajavidyalaya University
Year: 2017
Subjects: the Love; the Marriage; Theravada Buddhist Philosophy

description: Journal of MCU Peace Studies, 5, sp1
Cardiovascular adverse events in patients with HER2-positive breast cancer treated with trastuzumab-drug conjugates : a Bayesian disproportional real world study for signal detection leveraging the FDA Adverse Event Reporting System (FAERS)
Creators: name: Hu, Jinfang
name: Chen, Siyu
name: Jia, Huanhuan
name: Cai, Nvlue
name: Hu, Runlong
name: Chen, Xi
name: Guan, Yezhi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: The cardiovascular risk profiles of trastuzumab drug conjugates (T-DCs) in the treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer are uncertain. This study analyzed real-world adverse events data from the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) to investigate the association between T-DCs and major adverse cardiovascular events (MACE). We searched the FAERS database for reports of cardiovascular adverse events in patients with HER2-positive breast cancer receiving trastuzumab, ado-trastuzumab emtansine (T-DM1), and trastuzumab deruxtecan (T-Dxd). The primary endpoint was MACE and the secondary endpoint was other cardiovascular events. Between January 2015 and April 2024, out of the 135,226 drug-adverse event pairs analyzed, 8,497 were cardiovascular events, with 4,457 classified as MACE and 4,040 as other cardiovascular events. Trastuzumab reached pharmacovigilance for MACE (ROR = 1.39, 95%CI: 1.30–1.49, IC025 = 0.25), while neither T-DM1 (ROR = 0.78, 95%CI: 0.69–0.88, IC025=-0.51) nor T-Dxd (ROR = 0.63, 95%CI: 0.52–0.76, IC025=-0.93) reached MACE-related pharmacovigilance. Among MACE, stroke linked to T-DM1 (ROR = 1.86, 95%CI: 1.42–2.43, IC025 = 0.35) and T-Dxd (ROR = 2.44, 95%CI: 1.68–3.56, IC025 = 0.57) both reached pharmacovigilance in younger patients (<65 years). Proportionate analysis showed age and weight were the two key factors contributing to the occurrence of T-DCs induced MACE. HER2-positive breast cancer patients receiving T-DCs require additional cardiac monitoring, particularly for stroke in younger patients.
The Role of Leaders in Developing Local Community : A Case Study of Chief Executive of Nasiaw Sub-district Administrative Organization
Creators: name: Ketesuda Phoecanit
name: Nooyod, Keela
Publisher: name: Master of Arts Program in Peace Studies, Mahachulalongkornrajavidyalaya University
Year: 2017
Subjects: Role; Leaders Local Community; Local Government

description: Journal of MCU Peace Studies, 5, sp1
Wordsworth, Wittgenstein, and the Reconstruction of the Everyday
Creators: name: Ostas, Magdalena
Publisher: name: Humanities Commons
Year: 2011
Subjects: subject: Wordsworth, William, 1770-1850
subject: Wittgenstein, Ludwig, 1889-1951
subject: Literature--Philosophy

description: The connection between philosophy and real or everyday language belongs to Wordsworth’s early poetic vision. My interest in Wordsworth’s dialogue with philosophical thinking leads me to turn neither to studies tracing the varied philosophic influences on his poetics nor to those examining the influence of his collaborator Coleridge on his early poetic theory and practice. Instead, this essay turns to Wittgenstein, a philosopher who, very much like Wordsworth, gives almost exclusive and even obsessive attention to everyday language. This essay explores the deep and rarely noted conceptual affinity between Wordsworth’s conviction in the Preface to Lyrical Ballads that poetry should be written in “language really used by men” and Wittgenstein’s overarching desire in Philosophical Investigations to “bring words back from their metaphysical to their everyday use.” What occupies me in this essay is the epistemological priority both Wordsworth and Wittgenstein in this way assign to everyday language; I wonder throughout how it turns out in both Lyrical Ballads and Philosophical Investigations that the everyday is the philosophical, and how the singular attention to everyday language in both the case of the poet and the philosopher culminates in what one could call a novel epistemology.
A disproportionality analysis of hydrocortisone-related adverse events: a real-world pharmacovigilance study using the FAERS database
Creators: name: Wang, Xiaoyu
name: An, Fan
name: Zhao, Xuelian
name: Wang, Benjun
name: Yan, Liwei
name: Han, Weiwei
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: This study aims to systematically evaluate adverse events (AEs) associated with hydrocortisone through the FDA Adverse Event Reporting System (FAERS) database. AE reports associated with hydrocortisone from Q1 2014 to Q4 2023 were extracted from the FAERS database. Multiple disproportionality analysis techniques, including Reporting Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Empirical Bayes Geometric Mean (EBGM), were employed for signal detection. In addition, we also analyzed the time to onset of AEs. Analysis of 7,532 hydrocortisone-associated AEs from the FAERS database revealed significant signals across multiple system organ classes. The strongest associations were found in endocrine disorders (ROR: 13.39), ear and labyrinth disorders (ROR: 3.05), and immune system disorders (ROR: 2.17). Additionally, the study uncovered unexpected AEs such as splenic peliosis and lymphoid tissue hypoplasia. 63.9% of the AEs occurred within 7 days of treatment. Based on disproportionality analysis of FAERS data, this study provides new insights into the safety of hydrocortisone in the real-world setting. Future prospective studies should be conducted to validate the findings of this investigation.
sj-pdf-1-msj-10.1177_13524585211024997 – Supplemental material for Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study
Creators: name: Hartung, Hans-Peter
name: Derfuss, Tobias
name: Cree, Bruce AC
name: Sormani, Maria Pia
name: Selmaj, Krzysztof
name: Stutters, Jonathan
name: Prados, Ferran
name: MacManus, David
name: Schneble, Hans-Martin
name: Lambert, Estelle
name: Porchet, Hervé
name: Glanzman, Robert
name: Warne, David
name: Curtin, Francois
name: Kornmann, Gabrielle
name: Buffet, Bénédicte
name: Kremer, David
name: Küry, Patrick
name: Leppert, David
name: Rückle, Thomas
name: Barkhof, Frederik
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care

description: Supplemental material, sj-pdf-1-msj-10.1177_13524585211024997 for Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study by Hans-Peter Hartung, Tobias Derfuss, Bruce AC Cree, Maria Pia Sormani, Krzysztof Selmaj, Jonathan Stutters, Ferran Prados, David MacManus, Hans-Martin Schneble, Estelle Lambert, Hervé Porchet, Robert Glanzman, David Warne, Francois Curtin, Gabrielle Kornmann, Bénédicte Buffet, David Kremer, Patrick Küry, David Leppert, Thomas Rückle and Frederik Barkhof in Multiple Sclerosis Journal
sj-pdf-1-vdi-10.1177_10406387211027306 – Supplemental material for A novel Streptococcus species causing clinical mastitis in a pregnant donkey
Creators: name: Podico, Giorgia
name: Gray, Sarah M.
name: Wang, Leyi
name: Canisso, Igor F.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Supplemental material, sj-pdf-1-vdi-10.1177_10406387211027306 for A novel Streptococcus species causing clinical mastitis in a pregnant donkey by Giorgia Podico, Sarah M. Gray, Leyi Wang and Igor F. Canisso in Journal of Veterinary Diagnostic Investigation