cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Experiences and Expectations of Adolescents with Learning Disabilities and their Families as they Transition from Secondary School to Post-Secondary Education or Employment
Creators: name: Fullarton, Stephanie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: learning disabilities
transition planning
ecological systems theory
family systems theory

description: This qualitative study was designed to explore the transition experiences of youth with learning disabilities (LD) educated in the province of Ontario and their families. The primary purpose of this research was to understand what influences the decisions adolescents who have LD make about post-secondary education and employment goals and paths. The expectations and experiences of youth with LD and their families during the transition process were investigated. Adolescents and their parents were the main informants. Facilitators and barriers to the process in terms of each of the systems described in Bronfenbrenner ecological theory and Turnbull and Turnbull’s family systems theory were also examined. A case study method was used in the design of this research and data were collected following Seidman’s three-interview process. Five families consisting of the youth with LD, at least one parent, and in four cases, a sibling participated in this study. The questions focused on family interactions, roles, and the decision-making process. Data from the 18 participants were coded and arranged according to the research questions which were linked to the central ideas in the theoretical framework. The findings revealed that parents’ expectations influenced the decision-making about post high school goals and paths by the youth and their families. In contrast to previous research, it was found that parents’ expectations were generally high for their children with LD and were shaped by their own post high school experiences. The dynamics of family relationships and roles during transition planning depended on the time of diagnosis of LD (primary grades vs. senior high school), attitudes towards LD by the parents, advocacy by parents, self-advocacy abilities of the youth with LD, and the nature of relations among siblings. Additionally, none of the youth with LD had a formal transition plan and the data showed that teachers could facilitate or hinder the transition process. Also emerging from the data were three types of advocacy that were practised by parents. The study findings add to our knowledge about the transition process and in particular how decisions are made and the factors that influence them. Moreover, this study gives a voice to youth with LD and their families as they described their transition experiences to post-secondary education or employment.
Synchronising and separating permutation groups through graphs
Creators: name: Aljohani, Mohammed Hamoud
Publisher: name: The University of St Andrews
Year: 2022
Subjects: subject: Finite permutation groups
subject: Synchronisation
subject: Separation
subject: Association schemes
subject: Graphs
subject: QA175.A6

description: About 15 years ago, Araújo, Arnold and Steinberg introduced the notion of synchronisation to the theory of finite permutation groups. Synchronisation property is closely related to another property which is called separation, but they are not the same. Interestingly, the study of the two properties for finite groups involves many combinatorial problems. In this thesis, we tried to extend the current knowledge about synchronising and separating groups and suggest some questions. The introduction and the background are represented in Chapter 1 and Chapter 2, respectively. The main work is divided into three chapters. In Chapter 3, we started by extending the notions of synchronisation and separation to association schemes. Then, we considered two important families of almost simple permutation groups. Firstly, the group 𝐺 induced by the action of the symmetric group Sym(𝑛) on the set Ω of 𝑘-element subsets of an 𝑛-set, say {1, ..., 𝑛} (we call this the first group). Secondly, the group 𝐺 induced by the action of the symmetric group Sym(𝑛) on the set Ω of uniform 𝑙-partitions of an 𝑛-set, {1, ..., 𝑛}, into subsets of size 𝑘 where 𝑛 = 𝑘𝑙 (we call this the second group). For first group, when 𝑘 = 2, 3, 4 and 5, we showed that for large enough 𝑛 the group is non-separating (resp. non-synchronizing) if and only if there is a Steiner system S(𝑡, 𝑘, 𝑛) (resp. large set) for some 𝑡 < 𝑘. In general, we stated a conjecture that is if true would be a crucial extension of the remarkable result by Peter Keevash that considers the existence of Steiner systems. For the second group, we gave similar results to the first group when 𝐾 = 2, 3, 4, 5, 6 and 𝑙 = 2. We stated conjecture for 𝑘 > 6 and 𝑙 = 2. Also, we showed that the group is non-synchronising when 𝑙 > 2. In Chapter 4, the synchronisation property of a ne distance transitive permutation groups is considered. We showed that the separation and the synchronising properties are equivalent for a ne groups. We determined when some groups are synchronising, for example, automorphism groups of Hamming graphs, halved graphs, folded halved graphs, bilinear form graphs, some alternating form graphs and cosets graphs of some Golay codes. In addition, we stated a conjecture for distance regular graphs which connects this chapter and the previous one. In Chapter 5, we started by defining the diagonal factorisation of finite groups and proved some related basic results. Then, we showed that the diagonal group 𝐷(𝑇, 2) is non-separating if and only if 𝑇 admits a diagonal factorisation. Also, we showed that the group 𝐷(𝑇, 2) is non-separating when 𝑇 = 𝐴ₙ. We proved that the diagonal group 𝐷(𝑇, 𝑑) for 𝑑 ≥ 3, is non-synchronising. In the last section, we showed the equivalence between the separation and the synchronisation properties for groups of diagonal types.
Le choix des parents. Éducation, identité et religion en Ontario français : le cas d’Orléans
Creators: name: Nault, Jean-François
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: choix scolaire
éducation
identité franco-ontarienne
culture
religion
catholicisme
Ontario français

description: En effectuant un survol des recherches sur l'identité franco-ontarienne, il est possible de constater que l'accent a davantage été porté sur la question linguistique. Pour diverses considérations, la question du lien entre l'identité franco-ontarienne des dernières décennies et son héritage catholique a rarement été examinée. Or, force est de constater qu’il existe en Ontario français une certaine persistance du fait religieux au sein des communautés, mais aussi au sein du monde scolaire. Dans le cadre de cette thèse, nous entendons fournir des éléments de réponse à une partie de la question du lien entre l'identité franco-ontarienne et la religion catholique en procédant par l'analyse du milieu scolaire ontarien. Encore aujourd'hui, huit des douze conseils scolaires de langue française de l'Ontario sont catholiques. Bien que de nombreux travaux témoignent de l'importance du milieu scolaire comme terrain d'analyse de la reproduction culturelle et identitaire en Ontario français, peu de ces études s'attardent à l'examen de la place de la religion dans l'apprentissage culturel ou identitaire chez les étudiants franco-ontariens. À l’aide d’un corpus d’entretiens menés auprès de parents ayant fait le choix d’une école élémentaire catholique de langue française pour leurs enfants, cette recherche vise à déterminer l’importance des représentations identitaires et culturelles, en lien avec l’identité culturelle des Franco-Ontariens, dans les motivations du choix des parents d'envoyer leurs enfants à une école catholique de langue française à Orléans.
Kontrolnyje spiski dlja isutschenija i otschenki sostojanija promyschlennych objektow, imejuschtschich weschtschestwa, predstawljajuschtschije opasnost dlja wodnych resurcow
Creators: name: Winkelmann-Oei, Gerhard
name: Platkowski, Jörg
Publisher: name: My University
Year: 2015
Subjects: Wasserschutz
Wasserverunreinigung
Wasserschadstoff
Risikomanagement
Richtlinie

description: Based on recommendations by international river basin and water body commissions, a checklist concept was developed as a tool to efficiently evaluate the condition of installations handling substances and preparations hazardous to water. It comprises an overview of potential fields of action as well as specific checklists subdivided by functional units, sectors and risk areas.
Quelle: https://www.umweltbundesamt.de
The Application of Multiuser Detection to Spectrally Efficient MIMO or Virtual MIMO SC-FDMA Uplinks in LTE Systems.
Creators: name: Ben Salem, Aymen
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: SC-FDMA
Single Carrier Frequency Division Multiple Access
SC-FDE
3GPP Long Term Evolution
Single Carrier Systems
Single Carrier FDE
Single Carrier FDMA
Localized Subcarrier Mapping
Distributed Subcarrier Mapping
Orthogonal Frequency Division Multiple Access
OFDMA
MIMO SC-FDMA
Spatial Diversity Gain
Spatial Multiplexing Gain
MIMO Channel
SIMO Channel
Space Diversity on Receive Techniques
Selection Combining
Equal-gain Combining
Maximal-ratio Combining
MRC
Channel Equalization
Zero-forcing Equalization
Minimum Mean-square Error Equalization
ZF
MMSE
SC-FDMA with Multiuser Detection
Spectrally Efficient SC-FDMA with Multiuser Detection
Link Level Simulation
V-blast

description: Single Carrier Frequency Division Multiple Access (SC-FDMA) is a multiple access transmission scheme that has been adopted in the 4th generation 3GPP Long Term Evolution (LTE) of cellular systems. In fact, its relatively low peak-to-average power ratio (PAPR) makes it ideal for the uplink transmission where the transmit power efficiency is of paramount importance. Multiple access among users is made possible by assigning different users to different sets of non-overlapping subcarriers. With the current LTE specifications, if an SC-FDMA system is operating at its full capacity and a new user requests channel access, the system redistributes the subcarriers in such a way that it can accommodate all of the users. Having less subcarriers for transmission, every user has to increase its modulation order (for example from QPSK to 16QAM) in order to keep the same transmission rate. However, increasing the modulation order is not always possible in practice and may introduce considerable complexity to the system. The technique presented in this thesis report describes a new way of adding more users to an SC-FDMA system by assigning the same sets of subcarriers to different users. The main advantage of this technique is that it allows the system to accommodate more users than conventional SC-FDMA and this corresponds to increasing the spectral efficiency without requiring a higher modulation order or using more bandwidth. During this work, special attentions wee paid to the cases where two and three source signals are being transmitted on the same set of subcarriers, which leads respectively to doubling and tripling the spectral efficiency. Simulation results show that by using the proposed technique, it is possible to add more users to any SC-FDMA system without increasing the bandwidth or the modulation order while keeping the same performance in terms of bit error rate (BER) as the conventional SC-FDMA. This is realized by slightly increasing the energy per bit to noise power spectral density ratio (Eb/N0) at the transmitters.
Additional file 9 of A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth
Creators: name: Tu, Geraldine Xue En
name: Ho, Yoon Khei
name: Ng, Zhi Xu
name: Teo, Ke Jia
name: Yeo, Tseng Tsai
name: Heng-Phon Too
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: 60506 Virology

description: Additional file 9. Representative images and FACS profile of AD-MSCs transfected with 300 ng of CD::UPRT::GFP plasmid, in the presence or absence of the Enhancer.
Additional file 5 of A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth
Creators: name: Tu, Geraldine Xue En
name: Ho, Yoon Khei
name: Ng, Zhi Xu
name: Teo, Ke Jia
name: Yeo, Tseng Tsai
name: Heng-Phon Too
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: 60506 Virology

description: Additional file 5. Determination of the transfection efficiencies of various commercial carriers in AD-MSCs. One day post seeding of 50,000 AD-MSCs, cells were transfected with different gene carriers at various GFP encoded plasmid (PF463-CMV-GFP, PlasmidFactory) and gene carrier amounts. AD-MSCs were transfected with a Lipofectamine 3000, b Polyfect, c Transficient, and d Turbofect according to the manufacturer’s instructions. e For cells transfected with PEI, the protocol is detailed in methods and materials section. Two-day post transfection, AD-MSCs were harvested. Transfection efficiency and cell viability (Propidium Iodide exclusion assay) were determined using NucleoCounter®NC-3000™. For each gene carrier, the left and right graph bar presents % of GFP+ cells and % of cell viability (% of PI- population), respectively. Data represents mean ± SD, n = 3.
Additional file 16 of A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth
Creators: name: Tu, Geraldine Xue En
name: Ho, Yoon Khei
name: Ng, Zhi Xu
name: Teo, Ke Jia
name: Yeo, Tseng Tsai
name: Heng-Phon Too
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: 60506 Virology

description: Additional file 16. CD::UPRT::GFP_AD-MSCs were cocultured with U251MG™Z or U87MG™Z at the ratio of 1:10, in the presence or absence of 5FC. After seven days of incubation, images of the culture were captured. Representative images are presented.
Three-dimensional measurement using a single camera and target tracking
Creators: name: Iovenitti, Pio
Publisher: name: Swinburne
Year: 2024

description: This thesis involves the development of a three-dimensional measurement system for digitising the surface of an object. The measurement system consists of a single camera and a four point planar target of known size. The target is hand held, and is used to probe the surface of the object being measured. The position of the target is tracked by the camera, and the contact point on the object is determined. The vision based digitising technique can be used in the industrial and engineering design fields during the product development phase. The accuracy of measurement is an important criterion for establishing the success of the 3-D measurement system, and the factors influencing the accuracy are investigated. These factors include the image processing algorithm, the intrinsic parameters of the camera, the algorithm to determine the position, and various procedural variables. A new iterative algorithm is developed to calculate position. This algorithm is evaluated, and its performance is compared to that of an analytic algorithm. Simple calibration procedures are developed to determine the intrinsic parameters, and mathematical models are constructed to justify these procedures. The performance of the 3-D measurement system is established and compared to that of existing digitising systems.
Additional file 15 of A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth
Creators: name: Tu, Geraldine Xue En
name: Ho, Yoon Khei
name: Ng, Zhi Xu
name: Teo, Ke Jia
name: Yeo, Tseng Tsai
name: Heng-Phon Too
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: 60506 Virology

description: Additional file 15. Non-viral modified AD-MSCs displayed higher anticancer potency. AD-MSCs were modified with PEI plus Enhancer and lentivirus carrying CD::UPRT::GFP at various pDNA amount and MOI, respectively. Two- or five-day post transfection or infection, a the fluorescent images were captured. Representative images are shown. b Then, cells were trypsinised, pelleted and resuspended in 1XPBS for flow cytometry analysis. Cell modification efficiency was calculated as % of CD::UPRT::GFP+ cells normalized to the total number of cells as quantified by FACS. c The mean RFU of AD-MSCs modified with lentivirus at MOI5 and non-viral method at 75 ng pDNA as measured by FACS is presented, n = 3. d The merged flow cytometry histogram displays the expression profile of the unmodified AD-MSCs (grey), AD-MSCs modified with 75 ng pDNA (Green) and lentivirus at MOI5 (orange). Population with FITC higher than 106 RFU is defined as population with high transgene expression. e The % of population with high transgene expression is presented with the bar graph, n = 3. f AD-MSCs modified transiently with PEI + Enhancer or stably with lentivirus were harvested for coculture with HT1080 cell line. One day later, cells were treated with 100 μg/mL of 5FC for 5 days. At the end of the experiment, MTS assay was performed to measure the cell viability. Bar graph represents mean of cell viability (%) ± SD, n = 4. Significant differences between PEI + Enhancer and Lentivirus were calculated using two tailed Student’s t-test. **, P
Durability of High-temperature Absorber Coatings
Creators: name: Hosseini, Sahar
Publisher: name: The Australian National University
Year: 2024

description: Solar absorber coatings play a crucial role in concentrating solar power (CSP) plants by converting solar irradiance into thermal energy. The primary objective of the research presented in this doctoral thesis is to understand the optical and physical degradation mechanisms for such coatings while in operation. Such knowledge will assist future development of new coatings, with better durability and improved optical performance. This study focuses on three coatings: (1) Pyromark 2500, a coating in common use; (2) a so-called 'coral-structured coating' developed by industry partner Nano Frontier Technology (NFT); and (3) CoteRill750, a coating developed by John Cockerill. Aging mechanisms were studied for all three coatings using different accelerated aging tests. Isothermal aging tests at 800C and 900C showed that optical degradation of these coatings is primarily associated with changes in morphology and the formation of new phases. Analysis of coatings that failed mechanically during testing suggests key reasons for such failures include reduction in bonding strength owing to micro-defects and the formation of oxide layers, combined with stress caused by thermal expansion coefficient mismatch between layers. The coral-structured coating was found to be more resistant to thermal stress compared to Pyromark because of the macro- and micro-porous structures, which accommodate thermal stresses. For Pyromark, curing temperature was found to be an important factor in optical and mechanical stability. Isothermal aging testing cannot simulate conditions on a cloudy day, where coating temperatures may fluctuate significantly. Therefore, thermal cycling tests under a range of different conditions were conducted. The results showed that the combination of temperature ramping plus holding at high temperature accelerated aging mechanisms. Such mechanisms include diffusion, sintering and growth of oxide layers, which all contribute to optical degradation and reduction in the bonding strength between layers. Hence, this type of test is necessary for comparing the durability between different coatings. Further testing focussed on thermal cycling using on-sun and high-flux facilities, albeit for a shorter time. Another topic examined in this doctoral research is the measurement of coating emittance, which is a factor affecting emission loss from the receiver and efficiency at high temperatures.
Direct and Indirect Loss Evaluation of Storm Surge Disaster Based on Static and Dynamic Input-Output Models
Creators: name: Jin, Xue
name: Sumaila, Ussif Rashid
name: Yin, Kedong
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: Storm surge disaster is one of the biggest threats to coastal areas. Over the years, it has brought serious losses to the economy and environment of China’s coastal areas. In this paper, Guangdong Province is taken as the research object to evaluate the damage caused by storm surge disasters. First of all, regarding the three-industry classification standards of the National Bureau of Statistics, combined with the storm surge disaster assessment index system, the 10-sector storm surge disaster loss input-output table is compiled and analyzed. Secondly, the indirect economic losses of storm surge disasters between 2007–2017 are determined by calculating the direct and indirect consumption coefficients. Thirdly, based on the static input-output model, considering the time factor, the dynamic input-output model of storm surge disaster assessment is established to calculate the cumulative output loss under different recovery periods (30 days, 90 days, 120 days, 180 days, 360 days). The results indicate that: (1) the losses, after a storm surge, in the agricultural economy have the greatest impact on the manufacturing sector, and conversely, they have less effect on the science, education and health service sectors; as well as the construction sector; (2) taking the industry with the biggest loss ratio as an example, the recovery of damaged industries is relatively rapid in the early stage and tends to be stable in the later stage of recovery; (3) the total output loss calculated using the static input-output model is greater than that computed using the dynamic input-output model. Researching the assessment of the direct and indirect loss due to storm surge disasters is of great value and practical significance for the scientific and rational planning of the country’s production layout, the maintenance of social and economic stability and the protection of life and property.
Supplementary document for DETECTOR: Structural Information Guided Artifact Detection for Super-resolution Fluorescence Microscopy Image - 5403433.pdf
Creators: name: Gao, Shan
name: Xu, Fan
name: Li, Hongjia
name: Xue, Fudong
name: Zhang, Mingshu
name: Xu, Pingyong
name: Zhang, Fa
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: The supplemental document 1.
Additional file 1 of A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth
Creators: name: Tu, Geraldine Xue En
name: Ho, Yoon Khei
name: Ng, Zhi Xu
name: Teo, Ke Jia
name: Yeo, Tseng Tsai
name: Heng-Phon Too
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: 60506 Virology

description: Additional file 1. Schematic diagram of the CD::UPRT::GFP plasmid construct.
Scheduling disciplines for multimedia WLANs: embedded round robin and wireless dual queue
Creators: name: Ranasinghe, Ravindra S.
name: Andrew, Lachlan L. H.
name: Hayes, David A.
name: Everitt, David
Publisher: name: Swinburne
Year: 2024

description: Wireless local area networks have developed into a promising solution to support advanced data services in untethered environments. Selection of an efficient packet-scheduling scheme is important for managing the bandwidth while satisfying QoS requirements of active sessions having diverse traffic characteristics. The key difficulty is the distributed nature of the queues in the uplink, resulting in the scheduler having to trade off polling greedy stations against wasting resources by polling potentially idle stations. In order to address this, we propose a novel scheduling scheme, 'Embedded Round Robin', which dynamically classifies stations as 'busy' and 'clear'. We then extend the recently proposed Dual Queue scheduling discipline to the case of wireless networks.
Automatic Analysis of Dreams
Creators: name: Amini, Reza
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Emotions
Dreams
Automatic Analysis
Artificial Intelligence

description: In a scientific study of dream content, artificial intelligence has been utilized to automatically score dream content. An initial attempt focused on scoring for emotional tone of dream reports. The contribution of this thesis demonstrates methods by which accuracy of such a system can be improved beyond text-mining. It was hypothesized that data extraction based on psychological processes will provide significant information that would produce an accurate model. In our first article, the significance of words expressed in dream reports, along with their associated words was explored. Extraction and inclusion of these associations provided detailed information that improved automatic scoring of positive and negative affect even though these associations exhibited skewed distribution. The second article demonstrated how normalization of the data was possible and how it could result in a more accurate model. Our last article was able to demonstrate that the model can differentiate between male and female dreams.
A single nucleotide polymorphism assay sheds light on the extent and distribution of genetic diversity, population structure and functional basis of key traits in cultivated north American cannabis
Creators: name: Henry, Philippe
name: Khatodia, Surender
name: Kapoor, Karan
name: Gonzales, Britni
name: Middleton, Alexis
name: Hong, Kevin
name: Hilyard, Aaron
name: Johnson, Steve
name: Allen, Davis
name: Chester, Zachary
name: Jin, Dan
name: Rodriguez Jule, José C.
name: Wilson, Iain
name: Gangola, Manu
name: Broome, Jason
name: Caplan, Deron
name: Adhikary, Dinesh
name: Deyholos, Michael
name: Morgan, Michael
name: Hall, Oliver W.
name: Guppy, Brent J.
name: Orser, Cindy
Publisher: name: BioMed Central
Year: 2020

description: Background: The taxonomic classification of Cannabis genus has been delineated through three main types: sativa (tall and less branched plant with long and narrow leaves), indica (short and highly branched plant with broader leaves) and ruderalis (heirloom type with short stature, less branching and small thick leaves). While still under discussion, particularly whether the genus is polytypic or monotypic, this broad classification reflects putative geographical origins of each group and putative chemotype and pharmacologic effect. Methods: Here we describe a thorough investigation of cannabis accessions using a set of 23 highly informative and polymorphic SNP (Single Nucleotide Polymorphism) markers associated with important traits such as cannabinoid and terpenoid expression as well as fibre and resin production. The assay offers insight into cannabis population structure, phylogenetic relationship, population genetics and correlation to secondary metabolite concentrations. We demonstrate the utility of the assay for rapid, repeatable and cost-efficient genotyping of commercial and industrial cannabis accessions for use in product traceability, breeding programs, regulatory compliance and consumer education. Results: We identified 5 clusters in the sample set, including industrial hemp (K5) and resin hemp, which likely underwent a bottleneck to stabilize cannabidiolic acid (CBDA) accumulation (K2, Type II & III). Tetrahydrocannabinolic acid (THCA) resin (Type I) makes up the other three clusters with terpinolene (K4 - colloquial “sativa” or “Narrow Leaflet Drug” (NLD), myrcene/pinene (K1) and myrcene/limonene/linalool (K3 - colloquial “indica”, “Broad Leaflet Drug” (BLD), which also putatively harbour an active version of the cannabichrometic acid Synthase gene (CBCAS). Conclusion: The final chemical compositions of cannabis products have key traits related to their genetic identities. Our analyses in the context of the NCBI Cannabis sativa Annotation Release 100 allows for hypothesis testing with regards to secondary metabolite production. Genetic markers related to secondary metabolite production will be important in many sectors of the cannabis marketplace. For example, markers related to THC production will be important for adaptable and compliant large-scale seed production under the new US Domestic Hemp Production Program.
The Role of N-Acetyl-Aspartyl-Glutamate (NAAG) in the Modulation of NMDA Receptors
Creators: name: Khacho, Pamela
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: N-acetyl-aspartyl-glutamate (NAAG)
NMDA receptors
Protons
Neuroprotection
Hippocampus
Electrophysiology

description: Ischemic strokes cause excessive release of glutamate, leading to overactivation of N-methyl-D-aspartate receptors (NMDARs) and excitotoxicity-induced neuronal death. For this reason, inhibition of NMDARs has been a central focus in identifying mechanisms to avert this extensive neuronal damage. N-acetyl-aspartyl-glutamate (NAAG), the most abundant neuropeptide in the brain, is neuroprotective in ischemic conditions in vivo. Despite this evidence, the exact mechanism underlying its neuroprotection, and more specifically its effect on NMDARs, is currently unknown due to conflicting results in the literature. Here, we uncover a pH-dependent and subunit specific action of NAAG on NMDARs. Using whole-cell electrophysiological recordings on acute hippocampal slices from adult mice and on HEK293 cells, we found that NAAG increases synaptic GluN2A-containing NMDAR excitatory postsynaptic currents (EPSCs), while effectively decreasing extrasynaptic GluN2B-containing NMDAR EPSCs in physiological pH. Intriguingly, the results of our study further show that in low pH, which is a physiological occurrence during ischemia, NAAG depresses GluN2A-containing NMDAR EPSCs and amplifies its inhibitory effect on GluN2B-containing NMDAR EPSCs, as well as upregulates the surface expression of the GluN2A subunit. Altogether, our data demonstrate that NAAG has differential effects on NMDAR function based on subunit composition and extracellular pH levels. These findings suggest that the role of NAAG as a neuroprotective agent during an ischemic stroke is likely mediated by its ability to reduce NMDAR excitation. The inhibitory effect of NAAG on NMDARs and its enhanced function in acidic conditions makes NAAG a prime therapeutic agent for the treatment of ischemic events.
State-business relation in Post-Suharto Indonesia. The Political Economy of the Development and the Construction Sector in Jakarta
Creators: name: Widojoko, Johanes
Publisher: name: The Australian National University
Year: 2024

description: Abstract This study explores New Developmentalism, a governance paradigm introduced in Jakarta by Governor Joko Widodo (Jokowi) and his successor, Governor Basuki T. Purnama (Ahok) during 2012-2016. Under this paradigm, the provincial government mobilized the bureaucracy and regional state-owned enterprises (RSOEs) to improve public services and build infrastructure. It also took over public services previously contracted to the private sector. These policies increased citizen satisfaction, helping to underpin Governor Jokowi's victory in the 2014 presidential election and making Ahok a popular governor despite his minority ethnic and religious background. Jokowi and Ahok pursued New Developmentalism as a strategy to deal with systemic political vulnerability. As governor, Jokowi was an outsider among established Indonesian political and economic elites, while Ahok was vulnerable due to his minority background. As outsiders, both governors lacked access to existing patronage networks in Jakarta. To secure themselves politically, they instead strove to make maximum use of the resources available to them, including by using the bureaucracy and state-owned enterprises to deliver benefits to residents. To use government agencies in this way, Jokowi and Ahok decided they had to first reform the bureaucracy and RSOEs. They introduced numerous reforms to reduce corruption and transform the government agencies they led into coherent and effective organisations. To finance the increasing role of the government their approach entailed, they took measures to improve efficiency of budgetary spending and injected capital from unspent budgetary allocations into the province's state enterprises. Ahok also created additional sources of income, particularly by imposing new taxes on developers. However, New Developmentalism not only increased Jokowi and Ahok's popularity as governors, it also brought unintended consequences. By reforming public procurement, improving city amenities, dealing with flooding problems, and building big infrastructure projects, the governors inadvertently created strong opposition from various groups, not just poor people and small contractors pushed aside by such policies, but also big businesses and oligarchs. New Developmentalism triggered conflict and political resistance in 2016, not only against Governor Ahok in Jakarta but also President Jokowi at the national level. This policy thus increased the popularity of Jokowi and Ahok but also contributed to the rise of Islamic resistance that led to the defeat of Ahok in the 2017 gubernatorial election.
What Is Bullying? An Empirical Investigation Into the Construct Validity of Bullying as Measured and Defined.
Creators: name: McGugan, Margaret Jane
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Bullying
Measurement

description: Bullying is a subset of aggressive behaviour that is characterised by three features: intention to cause harm, repetitiveness, and an imbalance of power between the perpetrator of the aggression and his or her victim (Olweus, 2010). This definition is widely accepted and widely used in academic research on bullying (Cornell & Bandyopadhyay, 2010), but lacks empirical evidence of construct validity (Finkelhor, Turner, & Hamby, 2012). This dissertation explores the construct validity of bullying in two ways. The first study examines the validity of the definition of bullying in terms of its ability to predict student functioning and identify a distinct group. The second study examines the validity of a widely used bullying measurement strategy in terms of its ability to identify aggression that meets the definition of bullying. Marginal evidence for the construct validity of bullying as currently measured and defined was found. While the characteristics of bullying do predict several measures of functioning above and beyond the presence of generic aggression or victimization, the differences predicted appear to be differences of magnitude only. This indicates that bullying may be related to more severe, but not unique, outcomes. In addition, the individual characteristics of bullying contained within the overall definition (repetition, intention to harm, power imbalance) are shown to be highly related and better thought of indicators that bullying has occurred rather than additive constructs that define a certain subclass of aggressive behaviour. Finally, regarding measurement, the results of this study show that peer-report responses using definitional measurement strategies are not strongly related to the definitional criteria of bullying. Implications for the field of bullying research are discussed. Theoretically informed empirical work on clarifying the bullying construct is identified as a research priority.
Vers une théorie matérialiste du perfectionnement du jugement : corps de philosophe et philosophie du corps chez Diderot
Creators: name: Leduc, Éric
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Diderot
matérialisme
passions
corps
jugement

description: Cette thèse s’est donnée pour tâche de montrer que le jugement chez Denis Diderot (1713-1784) repose sur l’acte d’un corps, c’est-à-dire de montrer qu’il est possible uniquement à partir de la sensibilité et de la mémoire du corps humain de rendre compte de la complexité de ses jugements. Plus précisément, nous avons défendu l’idée que, chez Diderot, c’est le corps, par sa relative unité et stabilité, qui lie diverses sensations dans un jugement. À la lumière de la pensée de ce philosophe, ce travail se veut une première étape vers l’élucidation des rapports corporels qui peuvent stimuler ou entraver certains types de jugement et ultimement le perfectionnement du jugement.
Evolution of a staff development program in promoting quality online teaching
Creators: name: Weaver, Debbi
Publisher: name: Swinburne
Year: 2024

description: This paper describes a case study analysis of the evolution of an academic professional development program, related to the use of WebCT in teaching programs. It also discusses the changing nature of the staff developer role. The training program begins with face-to-face workshops, covering pedagogical issues as well as technical and practical aspects of the software. The workshop series has matured in its format and content in response to staff requirements and demands, as well as software upgrades. This paper describes the ongoing evolution of the workshop program, and discusses the changes the staff developer role has undergone, in relation to operational initiatives and contributions to organisational policy development.
Mechanics and Mechanotransduction of Adherent Cells: A Compendium of Atomic Force Microscopy Studies
Creators: name: Haase, Kristina M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: Cell mechanics
Atomic Force Microscopy
Mechanotransduction
Nuclear mechanics
Plasma membrane
Cytoskeleton

description: Mechanical cues have been recognized to be critically important in the regulation of cells. A myriad of cellular processes including differentiation, proliferation, and gene expression are all affected by physical forces from the extra- and intra-cellular microenvironments. Despite recent advances in nano-technologies, many questions still surround how cells sense and respond to forces. Through a series of studies, we demonstrate how both the structure and inherent mechanical properties of the cell affect their response to mechanical cues. We first develop a methodology to mechanically manipulate cells while simultaneously characterizing their deformations. Using combined atomic force and confocal microscopy techniques and through systematic examination we demonstrate the role of the cytoskeleton and nucleus in the deformability and shape change of epithelial cells. Mechanical properties have been used in recent years to identify diseased states, including cancer. With this in mind, we used HeLa cells as a model and characterized significant deformability of their plasma membrane and underlying cortex. Importantly, we demonstrate and characterize their ability to recover from large shape changes, which we also observed in other epithelial cells. Shape recovery is shown to be rapid and reliant upon the actin cytoskeleton and intracellular fluid flow. Although the nucleus does not contribute significantly to the deformation and recovery of HeLa cells, the importance of nuclear mechanics cannot be forgone. In vitro studies have shown that mechanical forces transmitted through the cell’s cytoskeleton critically affect nuclear mechanics and gene transcription processes. Many others have used simple models and isolated nuclei in an attempt to characterize nuclear properties. Thus, in a subsequent study, we examine the nucleus within intact cells. Nuclear shape change, in response to force, is shown to be complex and cannot be well-characterized by isotropic mechanical properties. Characterization of the mechanics of the cell, as demonstrated through our findings, is crucial in the field of biological physics. The aforementioned studies, written as scientific articles, are presented in the body of this thesis (Chapters 2-5). A review article that focuses on mechanotransduction and relevant examples using AFM as a tool for its examination acts as an introductory chapter.
Relationships on the line
Creators: name: Cashion, Joan
name: Palmieri, Phoebe
Publisher: name: Swinburne
Year: 2024

description: Student involvement with on-line education is rapidly on the increase as educational organisations use the information communication technologies (ICTs) for the delivery and/or enhancement of many of their courses. Student responses to this can be extremely positive, but that is not so in all cases. Some of the critical components of quality on-line learning are the interactions and relationships that happen through the medium and the success of the experience will depend on the interaction and responses between teacher and learner, or between the learners. The other relationship that is important with on-line learning is the relationship of the learner with the work. Self-motivation and self-discipline are essential to on-line learning. Vocational education and training (VET) students are not always necessarily ready for independent learning, and the blend of face-to-face with the use of the on-line technologies often provides the most successful, flexible solution for them. This paper presents learner perspectives on relationships through the on-line technologies. The research is part of a project commissioned by the National Centre for Vocational Educational Research to look at the 'Quality in On-line Learning: The Learner's View' in the VET sector.
A healthy environment in the WHO European Region
Creators: name: Tobollik, Myriam
name: Wolf, J.
name: Cervantes, K.
Publisher: name: My University
Year: 2023

description: Around 15% of all deaths could be prevented through healthier environments in the WHO European Region. This document gives an overview of the environmental burden of disease and additional relevant environment and health data and facts in the Region. As a preparation for the Seventh Ministerial Conference on Environment and Health taking place from 5-7 July 2023 in Budapest, it provides a starting point for discussing the current status of the field of environment and health and the actions that Member States can take to provide a healthy future for the entire Region. Key risk areas are addressed such as air pollution, water, sanitation and hygiene, chemicals, radiation and climate change. European cities and their health-care systems are fundamental sectors for environmental sustainability and are, therefore, also addressed. © World Health Organization 2023
The deadly waiting game
Creators: name: Browne, Peter
Publisher: name: Swinburne
Year: 2024

description: Ten minutes by taxi from the centre of Nairobi are the offices of the Refugee Consortium of Kenya. It’s here, on a still, warm afternoon, that Eva Maina — a young, quietly spoken law graduate — describes to me her work as a lawyer working with refugees from throughout East Africa. As she talks it becomes increasingly clear that the refugee ‘queue’, so frequently mentioned by Philip Ruddock, operates much more like a lottery. “There’s quite a gap,” she says, “between how things should be and how they are.” [Introduction]
Einführung in das elektronische Laborbuch eLabFTW
Creators: name: Strauß, Florian
Publisher: name: Zenodo
Year: 2024
Subjects: electronic lab notebook
eLabFTW

description: Im Rahmen eines Workshops (am 20.08.2024) der Landesinitiative Forschungsdatenmanagement Niedersachsen (FDM-NDS) wurde diese Präsentation als Einstieg in das elektronische Laborbuch eLabFTW gegeben. Bei eLabFTW handelt es sich um ein ELN, das einen generischen Ansatz verfolgt und als Open Source Software zur Verfügung steht. Nach einer kurzen Einführung in (elektronische) Laborbücher, wurden die grundlegenden Features von eLabFTW präsentiert. Im Anschluss an die Präsentation wurde mittels einer Live-Demo das ELN in Aktion gezeigt, dieser Teil des Workshops ist nicht in den Folien zu finden.
Additional file 1 of Championing women working in health across regional and rural Australia – a new dual-mentorship model
Creators: name: Wozniak, Teresa M.
name: Miller, Esther
name: Williams, Kevin J.
name: Pickering, Amelia
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Needs assessment questionnaire. Table S2. Catalyse Mentorship Program Workshops 1–5. Table S3. Evaluation questionnaires for mentors. Table S4. Evaluation questionnaires for mentees.
Construire une alternative à l’agriculture industrielle : Les organisations paysannes et la souveraineté alimentaire au Québec et à Oaxaca
Creators: name: Leveille, Lise-Anne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Souveraineté alimentaire
Polanyi
UNOSJO
Oaxaca
Québec
Agriculture
agroécologie
identité paysanne
multifonctionnalité
Économie politique
Union paysanne

description: Le régime agroalimentaire dominant, qualifié de corporatif, marchand et industriel, est le produit de la mondialisation néolibérale. Les tenants de ce libéralisme soutiennent qu’il n’existe pas d’alternative viable. Pourtant, en agriculture, les mouvements paysans proposent des alternatives plus justes et écologiques. En partant de ce point, la thèse répond aux questions suivantes : quelle est l’importance de ces mouvements dans la défiance au modèle dominant? Comment les organisations paysannes du Nord et du Sud s’approprient-elles et adaptent-elles l’idée de souveraineté alimentaire? Et comment tentent-elles de mettre en pratique les principes qui y sont associés? La thèse se construit autour de deux études de cas, l’Union paysanne au Québec et l’UNOSJO à Oaxaca, pour démontrer que les organisations paysannes du Nord et du Sud ont adopté et se sont approprié le concept de souveraineté alimentaire afin de promouvoir, de mettre en œuvre et de consolider des régimes agroalimentaires alternatifs plus écologiques et plus justes. Ces alternatives se construisent sur le respect des pratiques ancestrales et la construction d’une identité collective au sein des organisations. L’approche polanyienne permet de comprendre le contre-mouvement créé par les organisations paysannes s'opposant aux conséquences néfastes du modèle dominant qui met leur qualité de vie et leur survie en danger. L’approche de Gibson-Graham permet de saisir comment les organisations paysannes proposent des modèles alternatifs qui intègrent l’activité agricole au sein d’une économie plurielle, c’est-à-dire une économie qui intègrent les aspects culturels, politiques et écologiques.