cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Assessment of WRF model parameter sensitivity for high-intensity precipitation events during the Indian summer monsoon
Creators: name: Chinta, Sandeep
name: Jetti, Yaswanth Sai
name: Balaji, C
Publisher: name: arXiv
Year: 2020
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Numerical Analysis (math.NA)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Default values for many model parameters in Numerical Weather Prediction models are typically adopted based on theoretical or experimental investigations by scheme designers. Short-range forecasts are substantially affected by the specification of parameters in the Weather Research and Forecasting (WRF) model. The presence of a multitude of parameters and several output variables in the WRF model renders appropriate parameter value identification quite challenging. The objective of the current study is to reduce the uncertainty in the model outcomes through the recognition of parameters that strongly influence the model performance using a Global Sensitivity Analysis (GSA) method. Morris one-step-at-a-time (MOAT), GSA method, is used to identify the sensitivities of 23 chosen tunable parameters corresponding to seven physical parameterization schemes of the WRF model. The sensitivity measures (MOAT mean and standard deviation) are evaluated for eleven output variables, out of which some are surface meteorological variables and the remaining are atmospheric variables, which are simulated by the WRF model with different parameters. Twelve high-intensity four day precipitation events during the Indian summer monsoon (ISM) for the years 2015, 2016, and 2017 over the monsoon core region in India are considered for the study. Six out of 23 parameters have high MOAT mean in the case of almost all the model output variables indicating that these parameters have a considerable effect on the outcome of the simulations. MOAT mean values of a few parameters are noticeably small for all the model output variables, and thus the uncertainty associated with them has a negligible effect on the WRF model performance. The study also presents the physical insights into the trends of the parameter sensitivity.
description: 31 pages, 11 figures, 2 tables
Rezension zu: Baumert, Norbert (2008): Mit dem Rücken zur Wand. Übersetzung und Auslegung des zweiten Korintherbriefes, Würzburg: Echter, 384 Seiten.
Creators: name: Schwendemann, Wilhelm
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: In der Reihe Paulus neu gelesen ist nun der zweite Korintherbrief der letzte Kommentar, der in der ZfBeg vorgestellt wird. Baumert gehört zu jenen Paulusinterpreten, die die Uneinheitlichkeit des 2 Kor nicht glätten, sondern auf (mindestens) drei ursprüngliche Briefe zurückführen. Die Einteilung der angenommenen drei Briefe verläuft synchron zu den wiederholten Ankündigungen des (Wieder-)Kommens des Apostels nach Korinth (S. 359); verbunden sind die drei Briefe aus 2. Kor mit 1 Kor 16. Die Einteilung nach Baumert (S. 370): – APOLOGIE (= 2 Kor 2,14-7,3; Schluss: 1 Kor 16,1-11, mit Überbringer Timotheus), – TRÄNENBRIEF (= 2 Kor 10,1-13,10; Schluss: 1 Kor 16,21-24, mit Überbringer Titus); – FREUDENBRIEF (= 2 Kor 1,1-2; 1,3-2.13; 7,4-9.15; Schluss 2 Kor 13,11-13, mit Überbringer Titus).
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
title: Dissecting the Role of microRNAs in the Radiation Response of Human Prostate Cancer
Creators: name: El Bezawy, Rihan
Publisher: name: The Open University
Year: 2018

description: Radiotherapy is one of the gold standard treatments for non-metastatic prostate cancer (PCa), although development of radioresistance limits its effectiveness. Mounting evidence supports the ability of microRNAs to interfere with different radioresistance-associated pathways, suggesting their potential as radiosensitizers. To identify miRNAs likely to be involved in influencing PCa radiation response, we first performed miRNA profiling analysis of PCa cell lines exposed to photon irradiation. Based on their modulation upon radiation exposure, and their role in regulating pathways associated with radiation response we singled-out and characterized miR-23a-3p and miR-24-3p as potential radiosensitizer molecules in PCa, unrevealing a central role of miR- 23a-3p-IL-6 axis. In the framework of miRNAs downregulated in PCa and known to regulate genes relevant to radiation, miR-875-5p and miR-205 were identified. Reconstitution of miR-875-5p, the expression of which directly correlates with that of E-cadherin, was able to enhance radiation response in PCa cell lines and xenografts through EGFR direct targeting. Consistent with the established role of EGFR in sustaining epithelial-to-mesenchymal transition (EMT) and promoting DNA repair following radiation, we found that miR-875-5p reconstitution in PCa cells counteracted EMT and impaired DNA lesion clearance, mainly via impairment of EGFR-ZEB1 axis. Restoration of miR-205 was able to significantly enhance PCa sensitivity to radiation, in both cell and animal models. Specifically, we found that miR-205 radiosensitizing effect was imputable to the downregulation of PKC-ε. Consistent with PKC-ε well-established role in DNA damage repair, we found that pEGFR and, consequently, pDNA-PK levels were significantly reduced by miR-205 reconstitution, thus suggesting that miR-205 enhances PCa radiation response via disruption of PKC-ε−EGFR−DNA-PK axis. Overall, the results of this project support the clinical interest in developing novel therapeutic approaches based on miRNA reconstitution (miR-23a-3p, miR-875-5p and miR-205) to enhance PCa response to radiotherapy.
Rezension zu: Fried, Hédi (2019): Fragen, die mir zum Holocaust gestellt werden, Köln: DuMont Buchverlag, 160 Seiten.
Creators: name: Baert-Knoll, Valesca
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Die gebürtig aus Sighet stammende Holocaust-Überlebende Hédi Fried legt mit über 90 Jahren im Anschluss an ihre Autobiografie ein weiteres bedeutendes Zeugnis zur Erinnerungskultur angesichts des Holocaust ab. Fried wurde für ihre langjährige Aufklärungsarbeit als Zeitzeugin des Holocaust in diversen Schulen und Universitäten bereits mehrfach ausgezeichnet, u.a. mit dem Verdienstkreuz I. Klasse der Bundesrepublik Deutschland 2017. Nun zieht sie zu dieser Arbeit ihr Resümee und versucht durch die Veröffentlichung von Fragen, die mir zum Holocaust gestellt werden ihre Antworten für eine Zeit aufzubewahren, in der auch die letzten Zeitzeugen verstummt sein werden, die Fragen aber weiterhin in den kommenden Generationen (hoffentlich) existieren werden. In ihrem Vorwort beschreibt Fried, wie sie ihren persönlichen Überlebensbericht in eine Art Referentenvortrag für Schulen und Universitäten überführt und dazu die Inhalte pointiert, die ihrer Meinung nach von besonderer Relevanz sind, ohne dabei jemals die umfassende, existentielle Dimension ihrer Gesamterfahrung zu verlassen.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Global transcriptome analysis of novel stress associated protein (SAP) genes expression dynamism of combined abiotic stresses in Oryza sativa (L.): An in silico approach
Creators: name: Pandiyan Muthuramalingam
name: Jeyasri, Rajendran
name: Anthonymuthu Selvaraj
name: Dhamodharan Kalaiyarasi
name: Aruni, Wilson
name: Shunmugiah Thevar Karutha Pandian
name: Manikandan, Ramesh
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Genes encoding proteins with A20/AN1 zinc-finger domains, belonging to the stress associated protein (SAP) gene family, are present in all eukaryotes and play a decisive role in plant response to diverse physiological and molecular activities particularly on biotic and abiotic stresses (AbS). In this first and foremost study, global transcriptome analysis of members of the SAP gene family was carried out in C3 model- Oryza sativa (OsSAP) aiming at the identification of OsSAP genes activated in response to unique or Combined AbS (CAbS). Based on the available spatio-temporal and phytohormonal RNA-Seq expression profile datasets, nine OsSAP genes were filtered out and identified by a differential expression signature noted in various tissues as well as plant hormones. Comparative genome ideogram of OsSAP genes confirmed the orthologous collinearity with C4 panicoid genomes. Interactome of these genes, revealed the molecular cross-talks of OsSAP. Thus, the computational expression signature of OsSAP genes led to a better understanding of gene dynamism in diverse developmental tissues/organs. Transcriptional regulation analysis of key OsSAP genes in response to stress (drought and salinity) suggested the novel role of OsSAP1, OsSAP2, OsSAP5, OsSAP7, OsSAP8 and OsSAP11 in AbS. Altogether, the study provides deeper insights on molecular characteristics of OsSAP genes, which could be deployed further to decipher their precise functional roles in AbS responses.
Additional file 1 of The association between psychological characteristics and physical activity levels in people with knee osteoarthritis: a cross-sectional analysis
Creators: name: Uritani, Daisuke
name: Kasza, Jessica
name: Campbell, Penny K.
name: Metcalf, Ben
name: Thorlene Egerton
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Flow chart describing participant recruitment
Binodoxys mackaueri
Creators: name: Akhtar, Mir Samim
name: Dey, Debjani
name: Usmani, Mohd. Kamil
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Binodoxys
Binodoxys mackaueri

description: 46. Binodoxys mackaueri (Das and Chakrabarti)
 Trioxys (Binodoxys) mackaueri Das and Chakrabarti, 1989a: 365-372.
 Host. Melanaphis meghalayensis meghalayensis Raychaudhuri and Banerjee on Bamboo (Das and Chakrabarti 1989a).
 Distribution. Uttar Pradesh (Das and Chakrabarti 1989a).
  47. Binodoxys  oregama (Agarwala, Saha and Mahapatra)
 Trioxys (Binodoxys) oregama Agarwala, Saha and Mahapatra, 1987: 329-333.
 Host. Ceratovacuna sp.? perglandulosa Basu, Ghosh and Raychaudhuri on Grass (Agarwala et al. 1987).
 Distribution. Sikkim (Agarwala et al. 1987).
description: Published as part of Akhtar, Mir Samim, Dey, Debjani & Usmani, Mohd. Kamil, 2011, A catalogue of aphid parasitoids (Hymenoptera: Braconidae: Aphidiinae) from India, pp. 1-31 in Insecta Mundi 2011 (151) on page 9, DOI: 10.5281/zenodo.4531563
Experimenting with Convolutional Neural Network Architectures for the automatic characterization of Solitary Pulmonary Nodules' malignancy rating
Creators: name: Apostolopoulos, Ioannis D.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Medical Physics (physics.med-ph)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from time-consuming procedures. Deep Learning has been proven as a popular and influential method in many medical imaging diagnosis areas. In this study, we consider the problem of diagnostic classification between benign and malignant lung nodules in CT images derived from a PET/CT scanner. More specifically, we intend to develop experimental Convolutional Neural Network (CNN) architectures and conduct experiments, by tuning their parameters, to investigate their behavior, and to define the optimal setup for the accurate classification. For the experiments, we utilize PET/CT images obtained from the Laboratory of Nuclear Medicine of the University of Patras, and the publically available database called Lung Image Database Consortium Image Collection (LIDC-IDRI). Furthermore, we apply simple data augmentation to generate new instances and to inspect the performance of the developed networks. Classification accuracy of 91% and 93% on the PET/CT dataset and on a selection of nodule images form the LIDC-IDRI dataset, is achieved accordingly. The results demonstrate that CNNs are a trustworth method for nodule classification. Also, the experiment confirms that data augmentation enhances the robustness of the CNNs.
description: 22 pages. arXiv admin note: text overlap with arXiv:1409.4842, arXiv:1512.07108 by other authors
Falls risk in frail seniors : clinical and methodological studies
Creators: name: Donaldson, Meghan Gordon
Publisher: name: University of British Columbia
Year: 2011

description: Introduction. Falls in older adults are a significant cause of morbidity. Thirty percent of women and 25% of men aged 65 years and older fall at least once per year and 1% of falls result in hip fracture. The effectiveness of current falls prevention guidelines has not been tested. One intervention to prevent falls is strength and balance retraining. Aims. (1) to determine whether older women who present to the emergency department with a fall receive referrals consistent with published guidelines; (2) to determine whether a home-based strength and balance retraining program reduces fall risk as measured by a standardized physiological profile; (3) to undertake a review of falls prevention literature to assess the appropriateness of statistical methods; (4) to explore the use of the mean cumulative function to compare fall events between groups. Methods. (1) Telephone administered survey; (2) a randomized controlled trial (RCT) of the Otago Exercise Program versus standard care; (3) a systematic review of RCTs; (4) a simulation study of the mean cumulative function. Results. Thirty-two percent of women (95% confidence interval 21% to 43%) who fell reported a visit with their family physician and 24% (95% confidence interval, 14% to 34%) reported referral and care with a physiotherapist. The incidence rate ratio for falls for Exercise Program participants compared to standard care was 0.44 (95% CI 0.23-0.84). Among 84 published RCTs reviewed fewer than one third utilized statistical methods for recurrent events. The mean cumulative function is useful for graphically summarizing fall events over time. Summary. Presentation to an emergency department after a fall is not currently associated with care consistent with published guidelines. Strength and balance retraining shows promise of reducing falls risk and further studies with larger samples are warranted. The analysis of falls could be improved by employing appropriate recurrent events models and informative graphical summaries.
Molecular docking and molecular dynamics simulations of a mutant Acinetobacter haemolyticus alkaline-stable lipase against tributyrin
Creators: name: Anuar, Nurul Fatin Syamimi Khairul
name: Roswanira Abdul Wahab
name: Fahrul Huyop
name: Syazwani Itri Amran
name: Azzmer Azzar Abdul Hamid
name: Khairul Bariyyah Abd Halim
name: Hood, Mohammad Hakim Mohammad
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: We previously reported on a mutant lipase KV1 (Mut-LipKV1) from Acinetobacter haemolyticus which optimal pH was raised from 8.0 to 11.0 after triple substitutions of surface aspartic acid (Asp) with lysine (Lys). Herein, this study further examined the Mut-LipKV1 by molecular docking, molecular dynamics (MD) simulations and molecular mechanics-Poisson Boltzmann surface area (MM-PBSA) calculations to explore the structural requirements that participated in the effective binding of tributyrin and its catalytic triad (Ser165, Asp259 and His289) and identify detailed changes that occurred post mutation. Mut-LipKV1 bound favorably with tributyrin (−4.1 kcal/mol) and formed a single hydrogen bond with His289, at pH 9.0. Despite the incongruent docking analysis data, results of MD simulations showed configurations of both the tributyrin-Mut-LipKV1 (RMSD 0.3 nm; RMSF 0.05 − 0.3 nm) and the tributyrin-wildtype lipase KV1 (tributyrin-LipKV1) complexes (RMSD 0.35 nm; RMSF 0.05 − 0.4 nm) being comparably stable at pH 8.0. MM-PBSA analysis indicated that van der Waals interactions made the most contribution during the molecular binding process, with the Mut-LipKV1-tributyrin complex (−44.04 kcal/mol) showing relatively lower binding energy than LipKV1-tributyrin (−43.83 kcal/mol), at pH 12.0. All tributyrin-Mut-LipKV1 complexes displayed improved binding free energies over a broader pH range from 8.0 − 12.0, as compared to LipKV1-tributyrin. Future empirical works are thus, important to validate the improved alkaline-stability of Mut-LipKV1. In a nutshell, our research offered a considerable insight for further improving the alkaline tolerance of lipases.
Rezension zu: Lindner, Konstantin et al. (Hg.) (2017): Zukunftsfähiger Religionsunterricht: konfessionell – kooperativ – kontextuell, Freiburg: Herder, 454 Seiten.
Creators: name: Schwendemann, Wilhelm
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Das Buch ist das Resultat einer Tagung im März 2016 in Osnabrück zum kooperativ-konfessionellen Religionsunterricht; das auf der Tagung entwickelte zugehörige Positionspapier hat den Titel: Damit der Religionsunterricht in Deutschland zukunftsfähig bleibt: Konfessionell, kooperativ, kontextuell – Weichenstellungen für einen zukunftsfähigen Religionsunterricht. Die drei Stichworte zeigen die Richtung an, alle drei sind untereinander komplementär verbunden und aufeinander bezogen. Der konfessionell-kooperative Religionsunterricht, in der Hauptsache zwischen römischkatholischer und evangelischer Konfession, scheint im Moment die tragfähige Alternative zum konfessionellen Unterricht. Das Buch gliedert sich in fünf Kapitel und einen Ausblick: 1 Der Religionsunterricht auf dem Weg zu neuen Passungsverhältnissen 2 Figuren konzeptioneller Fundierung 3 Optionen organisatorischer Modellierung 2 Erfordernisse religionsdidaktischer Implementierung 5 Impulse aus der jüdischen und islamischen Religionspädagogik Bilanzierung und Ausblick Zu Kap.1: Elisabeth Naurath (S. 23 – 40) weist in ihrem Beitrag daraufhin, dass der Religionsunterricht immer wieder auf seine Zeitgemäßheit und Subjektorientierung zu überprüfen sei, um die gesellschaftlichen Aufgaben der interkulturellen und interreligiösen Dialog- und Friedensfähigkeit zu fördern. Beispielhaft verweist zum Beispiel Friedrich Schweitzer (S. 41– 54) auf das evangelische Glaubens- und Bildungsverständnis, das den konfessionellen Religionsunterricht als Basis benötige, um Lernenden die Möglichkeit existenzieller Auseinandersetzung zu eröffnen.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Rezension zu: Scholem, Gershom (2019): Poetica. Schriften zur Literatur, Übersetzungen, Gedichte, Berlin: Jüdischer Verlag im Suhrkamp-Verlag.
Creators: name: Feininger, Bernd
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Die Ausgabe wurde am Leibniz-Zentrum für Literatur- und Kulturforschung Berlin (ZfL) unter der Leitung seiner langjährigen Direktorin Sigrid Weigel erarbeitet. Sie gibt im Vorwort Hinweise auf die komplizierte Editionsgeschichte (S. 24f). Die Texte sind äußerst sorgfältig ediert, mit den notwendigen Überlieferungshinweisen versehen und fachlich-judaistisch kommentiert, was die Übersetzung hebräischer Begriffe miteinschließt (vgl. dazu »Zur Edition« S. 760 –762). Neben einer Bibliografie schließt der Band mit einem nützlichen Glossar und einem Personenverzeichnis. [...] Mit diesem Band ist die (Wieder-) Entdeckung des »literarischen Scholem«, die sich seit 1992 (Berliner Tagung) und 1996 (Potsdam zum 100. Geburtstag Scholems) abzeichnete und durch die Veröffentlichung seiner Tagebücher (1995 und 2000) beschleunigt wurde, definitiv gelungen und zugänglich. 44 der insgesamt 119 aufgenommenen Texte sind hier erstmals publiziert: Entwürfe, Notate, Fragmente, aber auch vollständige Aufsätze und Übersetzungen. Nach einer Hinführung Der literarische Scholem (S. 11– 25) ist der Band in sechs große Abschnitte gegliedert, diese werden jeweils kenntnisreich eingeleitet: I. Klage und Klagelieder (S. 27–129) II. Übersetzungen religiöser Texte (S. 131– 206) III. Sprach- und Übersetzungstheoretisches (S. 208 – 311) IV. Chaim Nachman Bialik und Samuel Josef Agnon a) Übersetzungen (S. 313 – 414) b) Kritiken (S. 415 – 521) V. Literatur und Kritik (S. 523 – 646) VI. Gedichte von 1914 bis 1974 (S. 648 –759)
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Geometrizing quantum dynamics of a Bose-Einstein condensate
Creators: name: Lyu, Changyuan
name: Lv, Chenwei
name: Zhou, Qi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We show that quantum dynamics of Bose-Einstein condensates in the weakly interacting regime can be geometrized by a Poincaré disk. Each point on such a disk represents a thermofield double state, the overlap between which equals the metric of this hyperbolic space. This approach leads to a unique geometric interpretation of stable and unstable modes as closed and open trajectories on the Poincaré disk, respectively. The resonant modes that follow geodesics naturally equate fundamental quantities including the time, the length, and the temperature. Our work suggests a new geometric framework to coherently control quantum systems and reverse their dynamics using SU(1,1) echoes. In the presence of perturbations breaking the SU(1,1) symmetry, SU(1,1) echoes deliver a new means to measure these perturbations such as the interactions between excited particles.
description: 6 pages (4 figures) + 3 pages (2 figures)
Empirical Research on Influence Factors of “Leading Enterprise +Farmer” Channel Stability—Taking Personal Relation as the Regulated Variable
Creators: name: DING Xinxin
name: LI Daosheng
name: CHEN Mojing
name: DING Xinxin
name: LI Daosheng
name: CHEN Mojing
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Formal control, Channel stability, Relationship, Influence factor

description: In the cooperation model of leading enterprise +farmer, channel stability is always a prominent problem. Based on previous researches, taking farmers in Hainan region as investigation object, the influence factors of channel stability of leading enterprise + farmer are studied by combining the background of formal contract and using the combination method of theory and demonstration. Contract item design, trading cost, product specificity, power structure, information asymmetry and social relationship are contained in analytic framework to establish theoretic model. Research results show that in formal channel management, when contract clause design is more explicit, product specificity is stronger, power structure is more balanced, information share degree is higher, and trading cost is lower, channel is more stable, and farmer’s willing to renew contract is stronger. Meanwhile, social relationship plays stronger regulation role.
Amygdalin as Multi-Target Anticancer Drug against Targets of Cell Division Cycle: Double Docking and Molecular Dynamics Simulation
Creators: name: Khattab Al- Khafaji
name: Tugba Taskin Tok
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Cell-division protein kinases (CDKs) are gorgeous examples of targets for the helpful treatment of cancer by using multi-target inhibitors. Specifically, targeting cell-division protein kinase1/cyclin B (CDK1/Cyclin B), cell-division protein kinase 2/cyclin A (CDK2/Cyclin A) and cell-division protein kinase 4/cyclin D1 (CDK4/Cyclin D1) are considered a safe strategy to over the toxicity complications which are emerging from low specificity. In this work, we conducted the double docking and molecular dynamics to explicate the effect of amygdalin upon conformational modifications of selected targets. Moreover, the principal component analysis (PCA) was employed to inspect the effect of amygdalin on the fundamental motions of the each protein as target. Docking results illustrated that the binding free energies of amygdalin (AMY) to CDK1/Cyclin B, CDK 2/Cyclin A and CDK 4/Cyclin D1 were to be -9.41, -9.02 and -10.6 kcal/mol, respectively. The PCA results disclosed that binding of the AMY minimized the fundamental dynamics of CDK1/Cyclin B and CDK2/Cyclin A. The obtained results can give an insight into inhibitory activity of amygdalin that could help in designing of potential inhibitors. In the other word, it can be used AMY to inhibit other mechanisms and/or hallmarks of cancer.
An Analysis of Government Behavior in China's Dairy Industry
Creators: name: LI Ming
name: LI Ming
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Government policy, Chinese dairy products, Local agricultural associations, Service purchase

description: The quality of agricultural products should be regulated and guided by the industrial association consisting of various links of agricultural production chain. The government has to purchase the regulatory services from agricultural associations. In the production of dairy products in China, the improper government intervention has been in violation of the socialist market economic law, resulting in damage to the node enterprises on the dairy production chain. Therefore, it is necessary to establish the agricultural associations to ensure the quality of agricultural products.
Rezension zu: Grözinger, Karl Erich (2019): Jüdisches Denken. Theologie – Philosophie – Mystik, Bd. 5: Meinungen und Richtungen im 20. und 21. Jahrhundert,Frankfurt am Main: Campus Verlag, 857 Seiten.
Creators: name: Krochmalnik, Daniel
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Nach 839 Seiten steht wie in Heiligen Büchern über einer Arabeske die Formel: Tam WeNischlam HaSefer BeEsrat HaEl Jitbarach, d.h.: Beendet und vollendet das Buch, mit Hilfe Gottes, Er sei gesegnet. Die Eulogie bezieht sich nicht nur auf den anzuzeigenden Band allein, sie schließt die 3.764 Seiten Text und 137 Seiten Bibliographie von Karl Erich Grözingers monumentalem Fünfbuch: Jüdisches Denken. Theologie, Philosophie und Mystik von der Bibel bis ins 21. Jahrhundert. Die bloßen Zahlen verdeutlichen schon die riesenhaften Ausmaße des Werkes, nicht zu reden vom vielgliedrigen Aufbau des Ganzen und der sorgfältigen Durchführung im Einzelnen. Der Verfasser schöpft aus dem Vollen, sein Werk wird zunehmend selbstreferentiell, mit Hilfe der Querverweise kann der Leser wie in einem Hypertext endlos durch dreitausend Jahre jüdischer Denkgeschichte navigieren. Die Geschichte des jüdischen Denkens wird als Gemäldegalerie mit Porträts von Denkern und Werken, neuerdings auch von Denkerinnen, sowie großen Panoramen von Denkbewegungen präsentiert (S. 669 –770).
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Additional file 3 of Effects of iron chelation therapy on the clinical course of aceruloplasminemia: an analysis of aggregated case reports
Creators: name: Vroegindeweij, Lena H. P.
name: Boon, Agnita J. W.
name: J. H. Paul Wilson
name: Langendonk, Janneke G.
Publisher: name: figshare
Year: 2020
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3. Detailed overview of published treatments for aceruloplasminemia.
Binodoxys rubicola
Creators: name: Akhtar, Mir Samim
name: Dey, Debjani
name: Usmani, Mohd. Kamil
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Binodoxys
Binodoxys rubicola

description: 48. Binodoxys rubicola (Shuja-Uddin)
 Trioxys (Binodoxys) rubicola Shuja-Uddin, 1973: 9-14.
 Host. Aphis gossypii on Solanum melongena, Capsicum frutescence (Subhrani et al. 2006), Rubus sp. (Shuja-Uddin 1973); A. ruborum longisetosus on Rubus ellipticus (Das and Chakrabarti 1989a).
 Distribution. Jammu and Kashmir (Shuja-Uddin 1973); Uttar Pradesh (Das and Chakrabarti 1989a); Manipur (Subhrani et al. 2006).
description: Published as part of Akhtar, Mir Samim, Dey, Debjani & Usmani, Mohd. Kamil, 2011, A catalogue of aphid parasitoids (Hymenoptera: Braconidae: Aphidiinae) from India, pp. 1-31 in Insecta Mundi 2011 (151) on page 10, DOI: 10.5281/zenodo.4531563
A short proof of generalized Jacobi-Trudi expansions for Macdonald polynomials
Creators: name: Lassalle, Michel
Publisher: name: arXiv
Year: 2004
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: We give an elementary proof of the development of Macdonald polynomials in terms of "modified complete" and elementary symmetric functions.
description: 12 pages, LaTeX
Rezension zu: Martin Buber Werkausgabe Bd. 12 (2017): Schriften zu Philosophie und Religion, Gütersloh: Gütersloher Verlagshaus 909 Seiten.
Creators: name: Schwendemann, Wilhelm
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Der zwölfte Band der Werkausgabe umfasst Texte aus den Jahren 1922 –1964, die sich insgesamt mit dem Verhältnis von Philosophie und Religion auf dem Hintergrund von Existenzfragen und dem dialogischen Ansatz Bubers beschäftigen. Religion als Gegenwart dürfte eine Vorstudie von Ich und Du sein. Grundlegende Texte sind neben Religion als Gegenwart, Die Religion als Wirklichkeit, Das Problem des Menschen, Zur Situation der Philosophie, Bilder von Gut und Böse, Gottesfinsternis u.a. Religion als Gegenwart sind acht Vorlesungen, die zwischen dem 15.1.1922 und 12.3.1922 im Freien Jüdischen Lehrhaus in Frankfurt a. M. auf Einladung Franz Rosenzweigs gehalten wurden. Die Vorträge waren Vorarbeiten zu Ich und Du; Buber und Rosenzweig versuchten in der deso- laten Lage nach dem Ersten Weltkrieg dem deutschen Judentum wieder auf die Beine zu helfen, weil die nichtjüdische Mehrheitsgesellschaft immer mehr mit Ressentiments auf die jüdische Bevölkerung reagierte und der Antisemitismus immer gewalttätiger wurde (S. 583). Ob Religion Gegenwart sei, die zur Vergangenheit werden könne, ist die Grundfrage Bubers. Er charakterisiert in diesen Vorträgen Religion als unbedingte Wirklichkeit, aus der der Mensch leben könne (S. 89). Relativierung und Funktionalisierung von Religion seien der Tod im Topf (S. 91). Religion ruhe auf dem Fundament einer Seinsbindung (S. 97); auch das Sittliche könne nicht mit dem Religiösen identifiziert werden (S. 100). Die Unabhängigkeit des Geistes spiegele sich in der Unabhängigkeit des Religiösen (S. 108) – Religion sei gerade kein schlechtsinniges Abhängigkeitsgefühl (gegen Schleiermacher) (S. 110). Für Buber gehört das Religiöse, Religion überhaupt, grundsätzlich in eine Ich-Du-Beziehung hinein (S. 117). Die Gefahr für jede Religion bestehe darin, sich in Ich-Es- Beziehungen zu verlieren. Religion brauche das Gegenübertreten zu einem DU [...]
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
The Distributional Stress-Energy Quadrupole
Creators: name: Gratus, Jonathan
name: Pinto, Paolo
name: Talaganis, Spyridon
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We investigate stress-energy tensors constructed from the delta function on a worldline. We concentrate on quadrupoles as they make an excellent model for the dominant source of gravitational waves and have significant novel features. Unlike the dipole, we show that the quadrupole has 20 free components which are not determined by the properties of the stress-energy tensor. These need to be derived from an underlying model and we give an example motivated from a divergent-free dust. We show that the components corresponding to the partial derivatives representation of the quadrupole, have a gauge like freedom. We give the change of coordinate formula which involves second derivatives and two integrals. We also show how to define the quadrupole without reference to a coordinate systems or a metric. For the representation using covariant derivatives, we show how to split a quadrupole into a pure monopole, pure dipole and pure quadrupole in a coordinate free way.
description: 42 pages, 2 figures. Accepted by Classical and Quantum Gravity. url=http://iopscience.iop.org/article/10.1088/1361-6382/abccde
Rezension zu: Kasper, Walter Kardinal (2020): Juden und Christen – das eine Volk Gottes, Freiburg: Herder, 160 Seiten.
Creators: name: Dausner, René
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Das neue Buch von Walter Kardinal Kasper ist ein Statement, ein leidenschaftliches Bekenntnis zum jüdisch- christlichen Dialog. Gerade in einer Zeit, in der antisemitische Klischees neu verfangen und Stereotypen auferstehen, von denen man anzunehmen geneigt war, dass sie endgültig ad acta gelegt worden seien, gerade in einer solchen Zeit des drohenden Rückfalls in den Antisemitismus, erscheint diese Publikation mit dem klaren und wahren Titel: »Juden und Christen – das eine Volk Gottes«. Im Vorwort, das vom Juni 2019 in Rom datiert ist, heißt es: »Ich hoffe, dass die Veröffentlichung ein Ansporn sein kann, dem leider neu aufflammenden Antisemitismus mit ganzer Kraft zu widerstehen. « (S. 11) Mit ganzer Kraft – theologisch geschulte Ohren können hier unschwer einen Anklang an das Schma Israel, das »Höre Israel«, erkennen, das nicht selten und nicht zu Unrecht als jüdisches Glaubensbekenntnis gedeutet wird: »Höre, Israel! Der HERR, unser Gott, der HERR ist einzig. Darum sollst du den HERR, deinen Gott, lieben mit ganzem Herzen, mit ganzer Seele und mit ganzer Kraft.« (Dtn 6,4f.) Das Bekenntnis zur Einheit von Juden und Christen ist somit von Beginn an als dogmatische Aussage höchsten Ranges zu werten.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Development and Application of Meteorological Disaster Monitoring and Early Warning Platform for Characteristic Agriculture in Huzhou City Based on GIS
Creators: name: WU Bin
name: LI Yanfang
name: LIU Shuangxi
name: WU Bin
name: LI Yanfang
name: LIU Shuangxi
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Characteristic agriculture, Meteorological and agricultural information monitoring, Fine weather forecast products, Meteorological disaster monitoring and early warning

description: Based on the needs of characteristic agricultural production for meteorological services in Huzhou City, we use C# programming language to develop the meteorological disaster monitoring and early warning platform for characteristic agriculture in Huzhou City. This platform integrates the functions of meteorological and agricultural information monitoring, disaster identification and early warning, fine weather forecast product display, and data query and management, which effectively enhances the capacity of meteorological disaster monitoring and early warning for characteristic agriculture in Huzhou City, and provides strong technical support for the meteorological and agricultural departments in the agricultural meteorological services.
Simultaneous measurement of the photodisintegration of 4He in the giant dipole resonance region
Creators: name: Shima, T.
name: Naito, S.
name: Nagai, Y.
name: Baba, T.
name: Tamura, K.
name: Takahashi, T.
name: Kii, T.
name: Ohgaki, H.
name: Toyokawa, H.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We have performed for the first time the simultaneous measurement of the two-body and three-body photodisintegration cross-sections of 4He in the energy range from 21.8 to 29.8 MeV using monoenergetic pulsed photons and a 4-pi time projection chamber containing 4He gas as an active target in an event-by-event mode. The photon beam was produced via the Compton backscattering of laser photons with high-energy electrons. The 4He(gamma,p)3H and 4He(gamma,n)3He cross sections were found to increase monotonically with energy up to 29.8 MeV, in contrast to the result of a recent theoretical calculation based on the Lorentz integral transform method which predicted a pronounced peak at around 26-27 MeV. The energy dependence of the obtained 4He(gamma,n)3He cross section up to 26.5 MeV is marginally consistent with a Faddeev-type calculation predicting a flat pattern of the excitation function. The cross-section ratio of 4He(gamma,p)3H to 4He(gamma,n)3He is found to be consistent with the expected value for charge symmetry of the strong interaction within the experimental uncertainty in the measured energy range. The present results for the total and two-body cross-sections of the photodisintegration of 4He are compared to previous experimental data and recent theoretical calculations.
description: 19 pages, 24 figures, accepted for publication in Phys. Rev. C
Surface-Gravity Inequalities and Generic Conditions for Strong Cosmic Censorship
Creators: name: Santiago-Germán, Wenceslao
Publisher: name: arXiv
Year: 2003
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Transforming Penrose's intuitive picture of a strong cosmic censorship principle, that generically forbids the appearance of locally naked space-time singularities, into a formal mathematical proof, remains at present, one of the most outstanding unsolved mathematical problems from the theory of gravitational collapse. Part of the difficulty lies in the fact that we do not possess yet a clear-cut understanding of the hypothesis needed for the establishment of some sort of strong cosmic censorship theorem. What we have is a selected list of solutions, which at first sight seem to go against cosmic censorship, but at the end they fail in some way. However, the space of solutions of Einstein's field equations is vast. In this article, we plan to increase one's intuition by establishing a link between certain inequalities for Cauchy-horizon stability and a set of generic conditions, such as a reasonable equation of state--which determines whether the space-time is asymptotically flat or not, an energy condition, and an hypothesis over the class of metrics on which Einstein's field equations ought to be solved to ensure strong cosmic censorship inside black-holes. With these tools in hand we examine the Cauchy-horizon stability of the theory created by Born and Infeld--whose action principle has been used as a prototype in superstring theory, and the singularity-free Bardeen's black-hole model.
description: 6 pages, 2 figures(type eps), REVTeX4
Characteristics and Optimization of Distribution of Rural Residential Area in Wangcun River Basin of Linfen City
Creators: name: ZHANG Xiaokun
name: XUE Longyi
name: ZHANG Xiaokun
name: XUE Longyi
Publisher: name: Unknown
Year: 2017
Subjects: subject: Agribusiness
subject: Wangcun River Basin, Rural residential area, Characteristics of distribution, Optimization model

description: As a carrier of rural population, rural residential area carries important functions such as rural production and life. This paper studied the characteristics of rural residential area and optimization model, to lay certain foundation for integrating urban and rural development and increasing economic income. With the aid of ArcGIS10.1 and Fragstats3.4 software, based on the theory of landscape ecology, it analyzed the distribution characteristics of residential area in Wangcun River Basin of Anze County, Linrfen City, Shanxi Province. Besides, according to distribution characteristics, it analyzed three optimization models: priority development model, retention limit development model, and migration development model.
Aktuelle Notizen
Creators: name: Münz, Christoph
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Ein Virus zwingt die Welt in die Knie – Papst und Roms Oberrabbiner betonen »Bande der Freundschaft« Der Ausbruch der Corona-Pandemie hat das gesellschaftliche, wirtschaftliche, kulturelle und religiöse Leben, wie wir es kennen, nahezu weltweit zum Stillstand gebracht. Unmittelbar betroffen davon waren auch alle interreligiösen Aktivitäten, wie etwa die zentrale Eröffnung der »Woche der Brüderlichkeit« in Dresden Anfang März, in deren Rahmen Bundeskanzlerin Angela Merkel mit der Buber-Rosenzweig-Medaille ausgezeichnet werden sollte. Sie musste abgesagt werden wie auch Hunderte von Veranstaltungen, die in diesem Kontext bundesweit durch die mehr als 80 Gesellschaften für christlich-jüdische Zusammenarbeit geplant waren.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Wandel einer chassidischen Botschaft: Martin Buber und Elie Wiesel über das Verhältnis von Gott und Mensch
Creators: name: Güler, Juliane
Publisher: name: Zeitschrift für christlich-jüdische Begegnung im Kontext
Year: 2021

description: Eines der Grundelemente des Chassidismus ist »das Band zwischen dem Menschen und seinem Schöpfer, zwischen der Handlung des einzelnen und die Auswirkungen dieser Handlung auf die himmlischen Sphären.« So beschreibt es Elie Wiesel in seinem Buch Chassidische Feier.2 Das Verhältnis Mensch – Gott wird von ihm als eine »wechselseitige Abhängigkeit zwischen Mensch und Himmel« beschrieben, bei der »jeder […] auf den anderen einwirken [kann].«3 Anhand einer Erzählung soll dieses Band im Vergleich mit den zwei wohl bekanntesten Autoren und Übersetzern chassidischer Erzählungen aus dem 20. Jahrhundert charakterisiert werden. Elie Wiesel (1928 – 2016) und Martin Buber (1878 – 1965) haben in ihrer Zeit und in ihrem jeweiligen Sprachraum durch ihre Übersetzungen entscheidend zur Verbreitung der chassidischen Lehre beigetragen. Ihre jeweils unterschiedlichen Zugänge und Beschreibungen der zentralen Lehre und Botschaft des Chassidismus sollen hier verglichen werden. So wie bei Buber der Fokus seiner Darstellung des Chassidismus im engen Zusammenhang mit seiner Philosophie von Ich und Du (1923) steht, so ist es bei Wiesel der Bezug zu seinem Werk Nacht (1956). Dem geht eine kurze allgemeine Einführung zum Chassidismus sowie zu seiner historischen und religiösen Besonderheit voraus. Im Anschluss werden die jeweiligen Beschreibungen beziehungsweise Charakterisierungen des Chassidismus seitens Buber und Wiesel vorgestellt. Wie definieren sie die chassidische Lehre und welche Bedeutung schreiben sie ihr zu? Ihre jeweils eigenen Prämissen und Deutungen werden exemplarisch anhand ihrer Übersetzung an einer chassidischen Erzählung dargelegt.
description: Zeitschrift für christlich-jüdische Begegnung im Kontext, Nr. 01-02 (2020): Erinnerungskultur im Wandel
Quantum Mechanics in Infinite Symplectic Volume
Creators: name: Isidro, J. M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We quantise complex, infinite-dimensional projective space CP(H). We apply the result to quantise a complex, finite-dimensional, classical phase space C whose symplectic volume is infinite, by holomorphically embedding it into CP(H). The embedding is univocally determined by requiring it to be an isometry between the Bergman metric on C and the Fubini-Study metric on CP(H). Then the Hilbert-space bundle over C is the pullback, by the embedding, of the Hilbert-space bundle over CP(H).
description: Picard group corrected