cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Application of organic fertilizers alter the physical and biogeochemical properties of agricultural topsoil and subsoil
Creators: name: Neumeier, Anke
name: Guigue, Julien
name: Ostovari, Yaser
name: Muskolus, Andreas
name: Holmer, Anna
name: Martens, Henk
name: Mešinović, Emina
name: Kögel-Knabner, Ingrid
name: Creamer, Rachel
name: Van Groenigen, Jan Willem
name: Vidal, Alix
Publisher: name: Zenodo
Year: 2021
Subjects: Organic amendments, Organic carbon stocks, subsoil , Vis-NIR

description: Sustainable agricultural practices aim to ensure the rebuilt of soil organic carbon (SOC) stocks and to sustain soil fertility. One of the levers is the use of carbon and nutrient inputs in the form of organic amendments, such as farmyard manure, slurry and biogas digestate. These organic fertilizers represent a promising alternative to the mineral fertilizers, which are mainly made from non-renewable resources. The use mineral fertilizers is indeed associated with an excessive use of natural resources and a loss of biodiversity. The effect of organic amendments compared with traditional mineral fertilizers on SOC stocks and soil fertility are uncertain in the longer-term. We aimed at investigating the effects of mineral and organic fertilizers (i.e., manure, pig slurry and biogas digestate) on topsoil and subsoil biogeochemistry, after eight years of application. For this purpose, we sampled soil cores down to a depth of one meter in a randomized field experiment in Germany, running since 2011. A full-profile assessment of the carbon and nitrogen distribution, stability and bioavailability was achieved using a combination of classical bulk physico-chemical analyses (e.g., SOC and nitrogen contents, texture, pH, bulk density) and state-of-the-art imaging techniques. Selected samples were analysed for aggregate size distribution, as well as organic carbon and nitrogen contents and allocation within these aggregates. Further, undisturbed core-samples were scanned using a hyperspectral camera in the Vis-NIR range to reveal hotspots of carbon storage at the soil profile scale. Soil carbon distribution was predicted as a function of spectral response, using a variety of machine learning approaches. The application of organic fertilizers (whatever their nature) resulted in higher SOC contents in the first 10 cm, as compared to the control and the mineral fertilizer treatments. The SOC stocks were + 21-33 % higher in the soil treated with organic fertilizers as compared to the control treatment. The application of mineral fertilizer or digestate, as compared to the control, resulted in higher relative amount of microaggregates (versus macroaggregates) (+ 19-40 %) in the soil down to 80 cm. These results will provide essential information to develop management strategies that increase nutrient recycling as well as SOC stocks.
description: vEGU21: Gather Online | 19–30 April 2021
Jamming transition of randomly pinned systems
Creators: name: Brito, Carolina
name: Parisi, Giorgio
name: Zamponi, Francesco
Publisher: name: arXiv
Year: 2012
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We consider a system of hard spheres close to jamming, where translation invariance is broken by pinning a randomly chosen set of particles. Using two different protocols, we generate two kinds of packings at the jamming point, isostatic and hyperstatic packings. In the case where the packings are isostatic, jamming transition is not affected by random pinning: the jamming density is only slightly reduced, a generalized isostaticity condition holds, the system is marginally rigid over the entire glass phase, and the typical structural signatures of jamming are unchanged. Besides, random pinning does not have effect on the vibrational modes of the amorphous system, at least on the time and length scale that we are able to probe. For packings that are hyperstatic at jamming, the microscopic properties of the system are strongly affected by the random pinning: the frozen degrees of freedom introduce an excess of constraints that drives the system far from the mechanical marginality conditions and stabilize the low frequency modes of the system, shifting them to higher frequencies. The distance from the isostatic point seems to be the only relevant parameter in the system in both cases. These two cases are in contrast with the behavior of the plane waves of a crystal: the whole spectrum in this case is shifted to higher frequencies as soon as some particles are pinned.
description: 7 pages, 7 figures; the paper has been improved and some errors have been corrected with respect to v1
Scaffold-freies 3D-Zellkulturmodell humaner Lungenkarzinomzellen unter veränderten Schwerkraftbedingungen auf der Random Positioning Machine
Creators: name: Dietz, Carlo
Publisher: name: Otto-von-Guericke-Universität Magdeburg
Year: 2020
Subjects: subject: Lungenkrebs
subject: Plattenepithelcarcinom
subject: Mikrogravitation
subject: 616.0277

description: Der Einfluss von Mikrogravitation auf das Plattenepithelkarzinom der Lunge wurde bisher nur in geringem Umfang untersucht. Experimente mit anderen Zelllinien haben gezeigt, dass der Einfluss von Mikrogravitation auf Zellen zur Bildung dreidimensionaler Zellkulturmodelle führen kann. Dabei kann es zu multiplen Veränderungen in der Zellmorphologie, im Zytoskelett, im Zellzyklus, der Gen- und Proteinexpression, der Apoptose und vieler weiterer zellulärer Prozesse kommen. Das Ziel der vorliegenden Arbeit war es zu untersuchen, welche Veränderungen bei Zellen des Plattenepithelkarzinoms der Lunge nach Kultivierung unter simulierter Mikrogravitation mittels der Random Positioning Machine (RPM) auftreten und ob sich dreidimensionale Zellkulturmodelle ausbilden. Die Zellen wurden über verschiedene Zeiträume in der RPM kultiviert und anschließend mikroskopisch und mittels RT-qPCR, WesternBlotting und TUNEL-Methode untersucht. Bereits nach 24 Stunden auf der RPM bildeten die Lungenkarzinomzellen dreidimensionale Strukturen. Die F-Aktinfasern waren konzentrisch angeordnet und akkumulierten unmittelbar unterhalb der Zellmembran. Die Expression aller untersuchten Tumorsuppressorgene war in den nicht-abgelösten (adhärenten) Zellen aus der RPM signifikant hochreguliert. SOX2 war das einzige Protoonkogen, bei dem sich eine Veränderung in der Expression zeigte. Die ebenfalls untersuchte Proteinsynthese korrelierte nur zum Teil mit der Genexpression. Darüber hinaus wurde eine erhöhte Apoptoserate in den Sphäroiden nach 24 und 72 Stunden beobachtet (88,55% und 86,43%). Somit konnte die Bildung dreidimensionaler Zellmodelle unter Mikrogravitationsbedingungen auch für plattenepitheliale Lungenkarzinomzellen nachgewiesen werden. Weiterhin zeigten sich vor allem in den Tumorsuppressorgenen Veränderungen in der Expression, zusätzlich konnte eine erhöhte Apoptoserate festgestellt werden.
Supplementary document for Im-SCC-FRET: Improved single-cell-based calibration of a FRET system - 6747398.pdf
Creators: name: Hu, Min
name: JIANG, XINZHUO
name: Cao, GengQiang
name: Liu, Zhi
name: Wu, Ge
name: Zhuang, Zhengfei
name: Chen, Tongsheng
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Im-SCC-FRET: Improved single-cell-based calibration of a FRET system: supplemental document
(Re)making place on Salt Spring Island, British Columbia : a tale told two ways
Creators: name: Steager, Tabitha Youngreen
Publisher: name: University of British Columbia
Year: 2014

description: This PhD dissertation is an ethnography of Salt Spring Island, British Columbia. Based on fourteen months of fieldwork, this dissertation explores how people define, imagine, and create place on Salt Spring Island and why creating place matters. I use the importance my research participants place on local food as a particular lens to give focus to this exploration of how place is made and re-made. Definitions of Salt Spring Island are complex and often contested and competing. On an island known for its physical beauty as well as an “alternative” approach to social relations and politics, Salt Spring Island is also a place where economic development competes with environmental preservation, affluence intersects with poverty, and residents grapple with concepts of insider versus outsider. Using in-depth ethnographic research methods that included long-term research in residence on Salt Spring Island as well as participatory visual ethnographic methods, I explore these contestations of place and examine how people mobilize various means to define Salt Spring Island for themselves. Using Salt Spring Island as an example, I attempt to show that the creation of place is one fraught with conscious and unconscious arguments about who has the right and the power to define place. Ultimately the place that I describe within this ethnography is one that I have co-created with my research participants during a particular space in time and it is therefore unique, as all of our experiences with place must be. In addition to the ethnography, this dissertation also attempts to tell a story about Salt Spring Island in an experimental manner using photographs made by participants and researcher, constructing a purely visual ethnography that is meant to be interpreted by the reader. In so doing, an additional definition or experience of place is created by each reader, thus further developing the exploration of how we create place.
Kinetic exchange opinion model: solution in the single parameter map limit
Creators: name: Chowdhury, Krishanu Roy
name: Ghosh, Asim
name: Biswas, Soumyajyoti
name: Chakrabarti, Bikas K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: We study a recently proposed kinetic exchange opinion model (Lallouache et. al., Phys. Rev E 82:056112, 2010) in the limit of a single parameter map. Although it does not include the essentially complex behavior of the multiagent version, it provides us with the insight regarding the choice of order parameter for the system as well as some of its other dynamical properties. We also study the generalized two- parameter version of the model, and provide the exact phase diagram. The universal behavior along this phase boundary in terms of the suitably defined order parameter is seen.
description: 14 pages, 9 figures
Interacting Spin-2 Fields
Creators: name: Hinterbichler, Kurt
name: Rosen, Rachel A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We construct consistent theories of multiple interacting spin-2 fields in arbitrary spacetime dimensions using a vielbein formulation. We show that these theories have the additional primary constraints needed to eliminate potential ghosts, to all orders in the fields, and to all orders beyond any decoupling limit. We postulate that the number of spin-2 fields interacting at a single vertex is limited by the number of spacetime dimensions. We then show that, for the case of two spin-2 fields, the vielbein theory is equivalent to the recently proposed theories of ghost-free massive gravity and bi-metric gravity. The vielbein formulation greatly simplifies the proof that these theories have an extra primary constraint which eliminates the Boulware-Deser ghost.
description: 42 pages, 3 figures. v3 alternative argument using constrained spatial vielbeins has been removed (see footnote 3)
Die Rolle des rechten Herzens bei der kardialen Resynchronisationstherapie : Eine echokardiographische Beobachtungsstudie
Creators: name: Wengler, Fabian Thomas
Publisher: name: Otto-von-Guericke-Universität Magdeburg
Year: 2020
Subjects: subject: Kardiale Resynchronisationstherapie
subject: 616.12

description: Bei der kardialen Resynchronisationstherapie (CRT) handelt es sich um eine etablierte Therapie bei systolischer Linksherzinsuffizienz und Linksschenkelblock. Ein Therapieansprechen in Sinne eines „reverse remodeling“ des linken Ventrikels (LV) (Responder) findet sich nur in 50 – 70 % der behandelten Patienten. In dieser Arbeit wurde im Rahmen einer single-center Beobachtungsstudie bei 101 Patienten der Einfluss der CRT auf das rechte Herz in Abhängigkeit vom Responder-Status (reverse remodeling: Reduktion linksventrikuläres end-systolisches Volumen (LVESV) > 15 % nach 6 Monaten) sowie der prädiktive Wert der rechtsventrikulären (RV) Morphologie und Funktion auf die LV- Response untersucht. Zum Ausgangszeitpunkt ließ sich bei den späteren Respondern (55,5 %) im Vergleich zu den Non-Respondern (44,5 %) kein Unterschied in der Linksherzfunktion, aber eine signifikant bessere Rechtsherzfunktion feststellen. Der proximale end-diastolische rechtsventrikuläre Ausflusstrakt (RVOT) Diameter und der rechtsventrikuläre Druck (RVP) konnten als unabhängige Prädiktoren für eine spätere LV Response vs. Non-Response herausgearbeitet werden. Im 2.Teil der Arbeit untersuchten wir den Einfluss der CRT auf die Rechtsherzfunktion und Morphologie. Sowohl spätere LV-Responder als auch Non-Responder zeigten eine verbesserte RV Morphologie und Funktion nach 6 Monaten, deren Ausmaß am ehesten durch Unterschiede der RV Nachlastbedingungen zum Ausgangszeitpunkt und deren Änderung durch die CRT erklärt werden können. Die Ergebnisse unterstreichen, dass RV Größe und Funktion über die enge Nachlastkopplung und eventuelle LV-RV- Interaktion die linksventrikuläre Funktionsstörung vor und nach der CRT sehr sensitiv wiederspiegeln. Zur Festigung der Ergebnisse sind aber weitere Studien erforderlich.
Attività di ricerca e uso dei materiali reperiti in Internet
Creators: name: Spedicato, Giorgio
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: A diversi lustri di distanza dalla diffusione di Internet in ambito accademico, vi è ancora in alcuni la convinzione che i materiali ivi pubblicati o reperibili costituiscano una sorta di immenso common liberamente appropriabile, sovrapponendo così la facilità di accesso a tali materiali con la libertà d'uso degli stessi. Le regole del diritto d'autore, tuttavia, trovano diretta applicazione anche nel contesto della Rete rendendo necessario un chiarimento sull'equivalenza tra alcuni atti compiuti in ambito digitale e le corrispondenti condotte in ambito analogico. In Internet, inoltre, sono nate e hanno trovato ampia diffusione regole sociali e giuridiche che mirano a derogare alle restrizioni poste dai diritti di proprietà intellettuale. Occorre dunque acquisire maggiore consapevolezza della "biodiversità" che caratterizza, da un punto di vista giuridico, i materiali disponibili in Rete in modo da dar vita a prassi operative corrette nell'ambito dell'attività di ricerca accademica.
Black hole thermodynamical entropy
Creators: name: Tsallis, Constantino
name: Cirto, Leonardo J. L.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: As early as 1902, Gibbs pointed out that systems whose partition function diverges, e.g. gravitation, lie outside the validity of the Boltzmann-Gibbs (BG) theory. Consistently, since the pioneering Bekenstein-Hawking results, physically meaningful evidence (e.g., the holographic principle) has accumulated that the BG entropy $S_{BG}$ of a $(3+1)$ black hole is proportional to its area $L^2$ ($L$ being a characteristic linear length), and not to its volume $L^3$. Similarly it exists the \emph{area law}, so named because, for a wide class of strongly quantum-entangled $d$-dimensional systems, $S_{BG}$ is proportional to $\ln L$ if $d=1$, and to $L^{d-1}$ if $d>1$, instead of being proportional to $L^d$ ($d \ge 1$). These results violate the extensivity of the thermodynamical entropy of a $d$-dimensional system. This thermodynamical inconsistency disappears if we realize that the thermodynamical entropy of such nonstandard systems is \emph{not} to be identified with the BG {\it additive} entropy but with appropriately generalized {\it nonadditive} entropies. Indeed, the celebrated usefulness of the BG entropy is founded on hypothesis such as relatively weak probabilistic correlations (and their connections to ergodicity, which by no means can be assumed as a general rule of nature). Here we introduce a generalized entropy which, for the Schwarzschild black hole and the area law, can solve the thermodynamic puzzle.
description: 7 pages, 2 figures. Accepted for publication in EPJC
Berufliche Rehabilitation für Menschen mit Behinderung - wer bekommt sie, wer nicht? ; Strukturen und Prozesse des Zugangs zu Leistungen zur Teilhabe am Arbeitsleben für erwerbsfähige hilfebedürftige Menschen
Creators: name: Schubert, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2010
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 613

description: Die Arbeit fragt für den Personenkreis gesundheitlich beeinträchtigter Leistungsempfänger nach Sozialgesetzbuch II nach institutionellen Strukturen sowie Arbeits- und Entscheidungsprozessen der Arbeitsverwaltungen hinsichtlich des Zugangs zu erwerbsbezogenen Teilhabeleistungen im Bereich Wiedereingliederung bei Rehabilitationsträgerschaft der Bundesagentur für Arbeit. Daten wurden mittels 32 Experteninterviews erhoben. Beim Zugang zu Leistungen zur Teilhabe am Arbeitsleben bestehen – bedingt durch sozialrechtliche Vorgaben – für Betroffene komplexe institutionelle Betreuungsstrukturen und -prozesse. In der institutionellen Praxis steht die schnelle und weniger die dauerhafte Re-Integration ins Arbeitsleben im Vordergrund (SGB II- versus SGB IX-Zielrichtung). Leistungsbewilligungsprozesse sind von Wirtschaftlichkeitsaspekten sowie einer Tendenz zu allgemeinen, kürzeren Leistungen geprägt. Inwieweit so das gesellschaftliche Ziel dauerhafter Teilhabe erreichbar ist, muss offen bleiben.
La sperimentazione antiplagio nella Facoltà di Economia di Rimini
Creators: name: Amoroso, Alessandro
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: L'intervento presenterà i caratteri principali della sperimentazione antiplagio attuata nella Facoltà di Economia di Rimini sin dagli inizi del progetto di ateneo. Saranno illustrati brevemente la metodologia adottata e i risultati ottenuti. Concluderanno l'intervento alcune considerazioni sul plagio in ambito didattico e sugli strumenti utilizzati.
On Orbifold Criteria for Symplectic Toric Quotients
Creators: name: Farsi, Carla
name: Herbig, Hans-Christian
name: Seaton, Christopher
Publisher: name: arXiv
Year: 2012
Subjects: subject: Symplectic Geometry (math.SG)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 53D20, 58A40 (Primary) 13A50, 14L24, 57R18 (Secondary)

description: We introduce the notion of regular symplectomorphism and graded regular symplectomorphism between singular phase spaces. Our main concern is to exhibit examples of unitary torus representations whose symplectic quotients cannot be graded regularly symplectomorphic to the quotient of a symplectic representation of a finite group, while the corresponding GIT quotients are smooth. Additionally, we relate the question of simplicialness of a torus representation to Gaussian elimination.
Untersuchungen zum Genexpressionsprofil von Neuroblastomzellen unter dem Einfluss von Retinoiden und Identifikation neuer Zielstrukturen
Creators: name: Neumann, Ingo
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2011
Subjects: subject: Online-Publikation
subject: Hochschulschrift
subject: 615

description: Das Neuroblastom (NB) ist ein extrakranieller solider Tumor im Kindesalter, der aus einer multipotenten Stammzelle der Neuralleiste hervorgeht. Bisher konnte gezeigt werden, dass die Behandlung von NB-Zellen mit Retinoiden mit einem reduzierten Tumorwachstum und Differenzierung einhergeht. Retinoide sind gegenwärtig fester Bestandteil der Therapie von NB-Patienten. Bis heute sind jedoch die aktuellen Behandlungsformen, insbesondere bei Patienten mit fortgeschrittenem Tumorstadium, aufgrund häufiger Rezidivbildung noch unbefriedigend und zu verbessern. Das Ziel der Untersuchungen war, die Wirksamkeit der Behandlungsmethoden bei NB-Patienten durch den Einsatz alternativer Retinoide wie all-trans Retinsäure (ATRA) oder Fenretinid (4-HPR) zu verbessern. Bei einer Stimulation von NB-Zellen mit ATRA und 4-HPR konnte eine Wachstumshemmung durch Arretierung in der G1-Phase sowie eine Differenzierung mit Neuriten-Bildung und verminderte Invasivität beobachtet werden. Anhand der DNA-Microarray-Analyse wurde die differentielle Genexpression von Retinoid-behandelten NB-Zellen untersucht. Hierbei konnte eine Herunterregulierung des proneuronalen Transkriptionsfaktors achaete-scute complex homolog 1 (ASCL1) und Notch-bindenden Liganden delta-like 1 (DLK1) in differenzierten NB-Zellen identifiziert werden. Eine direkte Inaktivierung von ASCL1 durch RNA-Interferenz induzierte eine Expression des IGF2-Gens, dem eine Beteiligung an der Differenzierung von NB-Zellen zugesprochen wird. Die verminderte Migration von Tumorzellen resultierte aus einer Herunterregulierung des Chemokinrezeptors CXCR4. Darüber hinaus regulierte ATRA und 4-HPR die Expression des zellulären Adhäsionsmoleküls ICAM-1 und Tyrosinkinase-Rezeptors c-KIT herauf. Die gesteigerte Expression von ICAM-1 führte zu einer Sensibilisierung der NB-Zellen für eine Bystander-Zelllyse durch zytotoxische T-Lymphozyten (CTLs). Die Überexpression von c-KIT korrelierte wiederum mit der erhöhten Empfindlichkeit gegenüber einer Behandlung mit einem Tyrosinkinase-Inhibitor. Möglicherweise stellt die Kombination aus Retinoiden und Tyrosinkinase-Inhibitoren eine zukünftige Therapieoption dar. Anhand der Ergebnisse konnte gezeigt werden, dass beide Retinoide das Genexpressionsprofil ähnlich regulierten und therapeutisch relevante Zielstrukturen zur Verbesserung der Behandlung generierten.
Additional file 1 of My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype
Creators: name: Zhou, Yadi
name: Zhao, Junfei
name: Fang, Jiansong
name: Martin, William
name: Li, Lang
name: Nussinov, Ruth
name: Chan, Timothy A.
name: Eng, Charis
name: Cheng, Feixiong
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Supplementary figure S1-S6. Figure S1. Diagram illustrating different types of nodetic versus edgetic perturbation leading to distinct phenotypes. Figure S2. Mutation rate is enriched in the ligand binding sites for these cancer types. Figure S3. Mutation rate is enriched in the phosphorylation sites for these cancer types. Figure S4. Correlation between the original results and new results by considering the amino acid specific background mutation rate and the amino acid composition for ligand-binding (LB) sites and post-translational modification (PTM) sites across 33 cancer types. Figure S5. Comparison of the results using different window sizes for the phosphorylation sites across all cancer types. Figure S6. Protein quantification is lowered in mutated phosphorylation sites than wild type sites in (A) breast invasive carcinoma, (B) colon adenocarcinoma, and (C) ovarian serous cystadenocarcinoma.
Additional file 1 of Zishen Pill alleviates diabetes in Db/db mice via activation of PI3K/AKT pathway in the liver
Creators: name: Wu, You
name: Sun, Boju
name: Guo, Xiaoyuan
name: Wu, Lili
name: Hu, Yaomu
name: Qin, Lingling
name: Yang, Tao
name: Li, Mei
name: Qin, Tianyu
name: Jiang, Miao
name: Liu, Tonghua
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: Additional file 1 Table S1. Elution program used in the UPLC system. Table S2. Primers used in qPCR analysis. Table S3. Characteristic chemicals identified from LC-MS/MS analysis. figure S1. ZSP showed no severe toxic effects on mice. a Food intake and water intake of mice (n=7). b Body length of mice (n=7). c Assessment of liver function of mice (n=7). Normal group: wt/wt mice treated with distilled water. Model group: db/db mice treated with distilled water. ZSP group: db/db mice treated with ZSP at 3.3g/kg/day. All data presented as mean ± SD. *p < 0.05, **p < 0.01, ***p <0.001, compared to the model group. #p < 0.05, ##p < 0.01, ### p < 0.001, compared to the normal group. n s. non-significant.
Capacity expansion of urban water supplies : a case of Accra-Tema metropolitan area, Ghana
Creators: name: Alhassan, Hadisu
Publisher: name: University of British Columbia
Year: 2014

description: The supply-demand gap of potable water in rapidly growing urban cities in developing countries has become a major challenge. This is potentially worsened by poor and superficial assessment of the complex parameters of water resources and treatment technologies regarding capacity expansion. The estimated daily demand of 150 million gallons in the Accra-Tema Metropolitan Area (ATMA) region of Ghana far outweighs the daily supply of 94 million gallons. In this study, the Analytic Hierarchy Process (AHP) approach, through the inputs of experts in the water industry in Ghana, is used to assign weights to the identified significant factors that impact on selecting the best alternative source for urban water supply capacity expansion in the ATMA region. Three alternative plants, alongside their respective sources, are considered — the Weija, the Kpong, and the Teshie Desalination plants. The decision criteria considered are environmental, economic, technical, and socio-cultural criteria, with each having sub-criteria. In analysing the pairwise comparative judgments by the experts, the environmental criterion was found to be the most important criterion with the highest priority weight, followed by the economic, the technical and the socio-cultural criteria. In the analysis, the Kpong treatment plant ranked first with a score of 36.1%. This was followed by the Weija and Teshie desalination plants, which scored 33.8 and 30.2% respectively. Sensitivity analysis on the model revealed that the model is sensitive to the environmental and economic criteria while being robust to the technical and socio-cultural criteria. Sensitivity, in relative terms, indicated that the resource availability sub-criterion is the most critical, while that of the energy sub-criterion proved the most critical in absolute terms.
Il servizio antiplagio e il Dipartimento di Scienze Mediche Veterinarie della Scuola di Agraria e Medicina Veterinaria dell'Università di Bologna
Creators: name: Roncada, Paola
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: La Facoltà di Medicina Veterinaria ha aderito alla sperimentazione antiplagio con tutti i corsi di Laurea. Pur trattandosi di sperimentazione, l’analisi con il programma antiplagio è stata resa obbligatoria, fin dall’inizio, per tutte le tesi sia di Laurea sia di Dottorato. L’intervento avrà l’obiettivo di evidenziare la peculiarità della sperimentazione presso la Facoltà di Medicina Veterinaria, il ruolo del referente nei confronti dei colleghi docenti, i vantaggi dell’utilizzo del programma antiplagio e alcune criticità.
A quantitative study of spin-flip co-tunneling transport in a quantum dot
Creators: name: Liu, Tai-Min
name: Ngo, Anh T.
name: Hemingway, Bryan
name: Herbert, Steven
name: Melloch, Michael
name: Ulloa, Sergio E.
name: Kogan, Andrei
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report detailed transport measurements in a quantum dot in a spin-flip co-tunneling regime, and a quantitative comparison of the data to microscopic theory. The quantum dot is fabricated by lateral gating of a GaAs/AlGaAs heterostructure, and the conductance is measured in the presence of an in-plane Zeeman field. We focus on the ratio of the nonlinear conductance values at bias voltages exceeding the Zeeman threshold, a regime that permits a spin flip on the dot, to those below the Zeeman threshold, when the spin flip on the dot is energetically forbidden. The data obtained in three different odd-occupation dot states show good quantitative agreement with the theory with no adjustable parameters. We also compare the theoretical results to the predictions of a phenomenological form used previously for the analysis of non-linear co-tunneling conductance, specifically the determination of the heterostructure g-factor, and find good agreement between the two.
description: 5 pages, 5 figures
L'esperienza di Ca' Foscari nel controllo antiplagio delle tesi di laurea
Creators: name: Cortesi, Agostino
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: Nell'intervento verrà illustrato il processo di gestione online delle tesi di laurea a Ca' Foscari, che dal 2011 prevede il controllo antiplagio mediante l'utilizzo del software Compilatio. Verranno presentati i dati sinora raccolti relativi all'utilizzo di tale sistema e le principali problematiche riscontrate.
Editorial - International Journal of Sustainable Energy Planning and Management Vol 19
Creators: name: Østergaard, Poul Alberg
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2019

description: This editorial introduces the 19th volume of the International Journal of Sustainable Energy Planning and Management. The volume present work on oil and electricity use in Africa, heating and cooling demands for buildings in Algeria, spot and futures markets in the Iberian electricity markets, transportation sector energy scenarios in Indonesia and corporate willingness to adopt renewable energy sources in Nigeria.
description: International Journal of Sustainable Energy Planning and Management, Vol 19 (2019)
Identifizierung von Protein-Protein-Interaktionen und strukturelle Charakterisierung der humanen Proteinkinase D2 mittels Massenspektrometrie-basierter Methoden
Creators: name: Häupl, Björn
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2018
Subjects: subject: 615

description: Die Etablierung einer kombinierten analytischen Strategie aus Affinitätsanreicherung, Proteinvernetzung und Massenspektrometrie ermöglichte aus zytosolischen und Golgi-Apparat-Proteinfraktionen die Identifizierung von insgesamt 39 Protein-Interaktionspartnern der humanen Proteinkinase D2 (PKD2). Diese zeigten sowohl bereits beschriebene als auch bisher unbekannte funktionelle Zusammenhänge zur PKD2 und erlaubten Rückschlüsse auf deren Rolle am Golgi-Apparat sowie auf assoziierte Wechselwirkungen mit zytosolischen Effektorproteinen. Hervorzuheben sind dabei der Arp2/3-Proteinkomplex und der AP-2-Proteinkomplex, die an der dynamischen Assemblierung des Zytoskeletts und der Regulation des zellulären Vesikeltransportes beteiligt sind. Zudem wurden mittels Proteinvernetzung und massenspektrometrischer Analyse der Vernetzungsprodukte molekulare Distanzbeschränkungen der PKD2 identifiziert. Diese können als Grundlage der Aufklärung von Struktur-Funktionsbeziehungen mit den identifizierten Protein-Interaktionspartnern in die Erstellung bzw. Validierung von PKD2-Strukturmodellen einfließen.
description: A combined analytical strategy comprising affinity enrichment, protein cross-linking and mass spectrometry enabled the identification of a total of 39 protein interaction partners of human protein kinase D2 (PKD2) from cytosolic and Golgi apparatus protein fractions. The identified binding partners revealed both already described and so far unknown functional relationships with PKD2 and provided insights into the role of PKD2 at the Golgi apparatus as well as regarding associated interactions with cytosolic effector proteins. In particular, the Arp2/3 protein complex and the AP-2 protein complex were identified, which are involved into the dynamic assembly of the cytoskeleton and the regulation of cellular vesicle transport. Furthermore, using protein cross-linking and mass spectrometric analysis of cross-linking products molecular distance constraints of PKD2 were identified. These could serve for the generation and validation of PKD2 structural models regarding the elucidation of structure-function relationships with the identified protein interaction partners.
L'esperienza della Facoltà di Scienze Politiche "Cesare Alfieri" di Firenze
Creators: name: Cellini, Erika
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: L’intervento ha l’obiettivo di presentare l’esperienza che la Facoltà di Scienze Politiche di Firenze sta vivendo riguardo alla sensibilizzazione di docenti e studenti rispetto alla questione del plagio. La Facoltà si serve infatti da qualche anno di un software antiplagio ad uso di docenti e studenti e sottopone a controllo obbligato le tesi triennali di tutti i corsi di laurea.
Le Mappe Strategiche come Risposta alle Pressioni dell’Ambiente Esterno
Creators: name: Francioli, Francesca
Publisher: name: ----
Year: 2021
Subjects: management accounting change, società di intermediazione mobiliare, MIFID II, Balanced Scorecard, strategy maps

description: Il settore finanziario sta attraversando a livello globale una fase di profondo cambiamento. Da un lato, le difficoltà della situazione macro-economica generale e la pervasività delle tecnologie digitali stanno influenzando alla radice le abitudini dei clienti, i loro comportamenti di acquisto e soprattutto le modalità e i canali relazionali. Dall'altro lato, nello scenario europeo, l'evoluzione del quadro normativo con l’introduzione della MIFID II ha introdotto forti elementi di novità in termini di apertura del mercato, trasparenza verso i clienti, flessibilità della rete distributiva. A fronte di un cambio del quadro di riferimento corrispondono variazioni nel modello di business e di approccio al mercato. Alla luce di queste considerazioni il presente intervento si pone l’obiettivo di illustrare la ridefinizione della strategia in una società di intermediazione mobiliare attraverso l’utilizzo di uno strumento di controllo di gestione come la Balanced Scorecard che, oltre ad esplicitare strategia e obiettivi, ha reso possibile un rafforzamento delle relazioni con i stakeholders, in primis clienti e lavoratori.
description: ----, Vol 12, No 2 (2021): ISSUE 2/2021
Witten spinors on nonspin manifolds
Creators: name: Degeratu, Anda
name: Stern, Mark
Publisher: name: arXiv
Year: 2011
Subjects: subject: Differential Geometry (math.DG)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Motivated by Witten's spinor proof of the positive mass theorem, we analyze asymptotically constant harmonic spinors on complete asymptotically flat nonspin manifolds with nonnegative scalar curvature.
description: revised version; aceepted in Communications in Mathematical Physics
Oil price and economic growth in Kenya: A trivariate simulation
Creators: name: Odhiambo, Nicholas M
name: Nyasha, Sheilla
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2019

description: In this study, the dynamic causal relationship between oil price and economic growth in Kenya has been explored during the period from 1980 to 2015. A trivariate Granger-causality framework that incorporates oil consumption as an intermittent variable – in an effort to address the omission-of-variable bias – has been employed. Using the newly developed ARDL bounds testing approach to co-integration and the Error-Correction Model-based Granger-causality framework, the results of the study reveal that there is distinct unidirectional Granger-causality flowing from economic growth to oil price in the study country. These results were found to apply both in the short run an in the long run. Thus, it can be concluded that in Kenya, it is the real sector that pushes oil prices up. Further, it is possible to predict oil price changes in Kenya – given the changes in economic growth.
description: International Journal of Sustainable Energy Planning and Management, Vol 19 (2019)
Multifractal analysis of complex networks
Creators: name: Wang, Dan-Ling
name: Yu, Zu-Guo
name: Anh, Vo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Dynamical Systems (math.DS)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 28A80, 05C82

description: Complex networks have recently attracted much attention in diverse areas of science and technology. Many networks such as the WWW and biological networks are known to display spatial heterogeneity which can be characterized by their fractal dimensions. Multifractal analysis is a useful way to systematically describe the spatial heterogeneity of both theoretical and experimental fractal patterns. In this paper, we introduce a new box covering algorithm for multifractal analysis of complex networks. This algorithm is used to calculate the generalized fractal dimensions $D_{q}$ of some theoretical networks, namely scale-free networks, small world networks and random networks, and one kind of real networks, namely protein-protein interaction networks of different species. Our numerical results indicate the existence of multifractality in scale-free networks and protein-protein interaction networks, while the multifractal behavior is not clear-cut for small world networks and random networks. The possible variation of $D_{q}$ due to changes in the parameters of the theoretical network models is also discussed.
description: 18 pages, 7 figures, 4 tables
La tesi "copia e incolla": un caso di studio sulle opinioni di studenti e professori
Creators: name: Tammaro, Anna Maria
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: La tesi in Italia ha valore "legale", cioè certifica che lo studente ha compiuto un percorso di studio con successo ed è stato in grado di compiere un lavoro finale di ricerca, pur se limitato. Eppure il valore "vero" delle tesi degli studenti è generalmente basso ed è stato peggiorato dalla diffusa pratica del "copia ed incolla". E' allora vero quanto afferma Nicholas che Internet ci rende stupidi!. 
Quando arrivano nelle università, gli studenti non vengono istruiti sulle metodologie da seguire per redigere un lavoro di ricerca «corretto». Come anche non vengono istruiti sulle modalità di ricerca bibliografica e di citazione bibliografica. Sembra inoltre che si sia arrivati ad un clima di tolleranza per il fenomeno di "copia ed incolla" a lungo considerato quasi fisiologico! 
Un possibile cambiamento potrebbe essere stimolato con l' introduzione sul mercato di software specifici anti «copia e incolla». È il caso di «Turnitin», il sistema più diffuso. 
La presentazione descrive i risultati di un'indagine realizzata presso gli studenti del corso Editoria Digitale ed alcuni professori dell'Università di Parma.
A Raman and scanning electron microscope analysis of magnetron sputtered thin-film carbon
Creators: name: Laumer, Jonathan
Publisher: name: University of British Columbia
Year: 2015

description: Thin-film carbon coatings possess properties, such as extreme hardness, smoothness, and a nice glossy finish, that make them desirable for a variety of industrial and military applications. This thesis examines the Raman spectra associated with thin-films of carbon that are prepared using magnetron sputtering. The goal is to achieve a high amount of strong bonds, i.e., sp³ bonds, as in diamond, using this inexpensive and widely available deposition process. Raman spectroscopy is the chosen analytical method used for the purpose of this work, since it is non-destructive and widely available. Using Raman spectroscopy, an sp³ content of up to 77 % is determined. This suggests that it is possible to deposit thin-films of carbon that approach the properties of tetrahedral amorphous carbon, a material known for its excellent hardness and durability, using this inexpensive approach. A scanning electron microscope image of one of the thin-films of carbon is acquired and examined, conclusions regarding the transition between the underlaying titanium substrate and the thin-film of carbon being drawn. Further directions for possible research are mentioned.
Case study - Implementing a plagiarism detection service: ways of working with staff and students
Creators: name: Cohen, Judy
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2012
Subjects: M-STO/08 Archivistica, bibliografia e biblioteconomia

description: The session will outline how Turnitin was introduced to the University of Kent in 2006 and then implemented over the following academic year, including recent follow-up developments. The University Guidelines on Using Turnitin will be discussed, along with the use of specific Academic Integrity resources to support the use of Turnitin. There will be information about how staff are using Turnitin; how it has been received by students; the impact on reported instances of plagiarism (in specific Schools) and how staff view Turnitin in terms of workload and teaching academic writing.
Power Accessibility, Fossil Fuel and the Exploitation of Small Hydropower Technology in Sub-Saharan Africa
Creators: name: Ebhota, Williams S.
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2019

description: This study overviews the power status, salient barriers to adequate power access and the role of small hydropower in improving power accessibility in the region. The study notes that – over 50% of the population in 41 countries in the region have no access to electricity; the prediction of electricity access growth rate in SSA from 43% in 2016 to 59% in 2030; about 607 people, which is 90% of world’s population without access to electricity in 2030 will leave in the region and the rural areas access is below 20%; over 90% of the households in about 25 countries of SSA rely on waste, wood, and charcoal for cooking; the average grid power tariff in SSA is US$0.13 per kWh as against the range of US$0.04 to US$0.08 per kWh grid power tariffs in most parts of the developing world. Also, it was found that the sections of power supply system – generation, transmission and distribution facilities are affected by insufficient funding, poor maintenance and management and over dependence on foreign power supply technologies; and the region is endowed with huge SHP resource that is insignificantly tapped. Lack of workable SHP development framework; insufficient fund; effect of the electricity market in the region; lack of effective synergy among the stakeholders; insufficient and outdated hydrological information about SHP resources; inadequate human and manufacturing facility development were the identified factors responsible for SHP underdevelopment. Domestic development of SHP technology is required to effectively develop SHP to improve access to power in the region. This will require massive human capacity building and the use of locally soured materials and production facilities.
description: International Journal of Sustainable Energy Planning and Management, Vol 19 (2019)
Low carbon-based energy strategy  for transportation sector development
Creators: name: Setiartiti, Lilies
name: Al Hasibi, Rahmat Adiprasetya
Publisher: name: International Journal of Sustainable Energy Planning and Management
Year: 2019

description: This study presented the development of alternative scenarios of energy planning for the transportation sector. The case study is the transportation system of Yogyakarta Province of Indonesia. The transportation sector has the highest demand of energy among all another sector in this Province. Therefore, this sector has a very significant contribution to emit Greenhouse Gas pollutant. Four individual scenarios ware developed which are Business as Usual, Mode Change, Fuel Switch, and Efficient Vehicle. Business as Usual scenario is a reference scenario, and the last three scenarios are alternative scenarios. Also, an integrated scenario that consists of all alternative scenarios was also developed. The analysis of the projection of energy demand and Greenhouse Gas emission, in the form of CO2, NOx, and CH4, was conducted. The contribution of developed scenarios in low-carbon energy planning for the transportation sector was analyzed. Long-range Energy Alternative Planning software was utilized to simulate all developed scenarios. As an individual scenario, efficient vehicle scenario resulted in the highest reduction in energy demand. At the end of the projection period, this scenario reduced energy demand for the transportation sector by 15.82% compared to the reference scenario. Mitigation scenario that integrates all alternative scenarios reduced energy demand by 20.45% compared to the reference scenario in 2050. By implementing an efficient vehicle scenario, global warming potential can be reduced by 15.80%. The implementation of an integrated scenario reduced global warming potential by 24.76% compared to the reference scenario.
description: International Journal of Sustainable Energy Planning and Management, Vol 19 (2019)
A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data
Creators: name: Li, Heng
Publisher: name: arXiv
Year: 2012
Subjects: subject: Genomics (q-bio.GN)
subject: FOS: Biological sciences

description: Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample low-coverage sequencing or somatic mutation discovery). These applications press for the development of new methods for analyzing sequence data with uncertainty. Results: We present a statistical framework for calling SNPs, discovering somatic mutations, inferring population genetical parameters and performing association tests directly based on sequencing data without explicit genotyping or linkage-based imputation. On real data, we demonstrate that our method achieves comparable accuracy to alternative methods for estimating site allele count, for inferring allele frequency spectrum and for association mapping. We also highlight the necessity of using symmetric datasets for finding somatic mutations and confirm that for discovering rare events, mismapping is frequently the leading source of errors. Availability: http://samtools.sourceforge.net. Contact: hengli@broadinstitute.org.
description: The published version (open access now) with addition of a test for multi-allelic sites