cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Gammarus paraorientalis G. Kar.
Creators: name: Karaman, Gordan S.
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Amphipoda
Gammaridae
Gammarus
Gammarus paraorientalis

description: GAMMARUS PARAORIENTALIS G. Kar. (new name)
 Rivulogammarus balcanicus orientalis S. Karaman, 1934: 131, fig. 4;
 Gammarus balcanicus (part.) G. Karaman & Pinkster, 1987: 211.
 Gammarus orientalis G. Karaman 2017: 640, figs. 1-8.
 Remarks.
 Stanko Karaman described (1934) Rivulogammarus balcanicus orientalis n. ssp. from Derbend, eastern site of Erdschias- dag (=Erciyas-dagi), Asia Minor, 2100 m about sea level.
 G. Karaman & Pinkster (1987) removed Gammarus balcanicus orientalis to Gammarus balcanicus Schäferna 1922 as synonym. Later G. Karaman (2017) redescribed orientalis from type locality and elevated it to the specific rank, Gammarus orientalis (S. Karaman 1934).
 Recently we observed that Dana (1852) already have been described one amphipod species as Gammarus orientalis, n. sp. from “Hab. in mari prope fretum Sunde”. By this way the species Gammarus orientalis (S. Karaman 1934) became “nomen preoccupatum” and we proposed a new name for it, Gammarus paraorientalis G. Kar. (new name) with type locality: Derbend, eastern side of Erdschias-dag [=Erciyas-dagi] in Asia Minor.
description: Published as part of Karaman, Gordan S., 2018, On two partially known species of the genus Gammarus Leach 1813 / 14 (Fam. Gammaridae) from Asia Minor (Turkey) (Contribution to the Knowledge of the Amphipoda 304), pp. 110-124 in Ecologica Montenegrina 19 on page 123, DOI: 10.37828/em.2018.19.12, http://zenodo.org/record/13360085
Additional file 2 of Fabrication of a plasmonic-nose sensor for rapid identification of plant pathogenic bacteria based on optoelectronic analysis
Creators: name: Morelos-Pacheco, Mariela
name: Arellano-Alcántara, Marco A.
name: Olivares-Peralta, Jonatan
name: Colmenero-Solís, Raul
name: Saniger-Blesa, José M.
name: Cancino-Díaz, Juan C.
name: Widén, Joakim
name: Chávez-Ramírez, Belén
name: Mendoza-Figueroa, José Silvestre
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Additional file 2: Table S1. Parameters for the sample identification and extraction process and values for the example image in Fig. 3.
Entrepreneurial immigrants: the cost of failure
Creators: name: Cruickshank, Prue
Publisher: name: Swinburne
Year: 2024

description: Business immigration policies are predicated on the basis that entrepreneurial immigrants bring value to their new country's economy (BERL & NZIS, 1999; Nana, Sanderson, Goodchild, & BERL, 2003; NZIS, 1997). The barriers faced by business immigrants, especially those who speak English as a second language, are well documented (Fletcher, 1999; Ho, Cheung, Bedford, & Leung, 2000). In large cities these barriers have traditionally been overcome by such immigrants utilizing the ethnic social capital available within their communities (Portes & Sensenbrenner, 1993). However, studies of immigrant entrepreneurs have occurred in large cities such as Toronto, Miami, and New York. What happens when immigrants enter a smaller population in Auckland, New Zealand, where small, ethnic immigrant populations are less able to sustain new immigrant businesses?
Nurses’ Knowledge, Attitudes and Documentation Practices in a Context of HIV Criminalization: A Secondary Subgroup Analysis of Data from California, Florida, New York, and Texas Nurses
Creators: name: Domingue, Jean-Laurent
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: HIV
Criminalization
Nurses
Nursing Practice
Criminal Law

description: Under international legal norms, HIV criminalization is considered to be an overly broad use of criminal law. In the United States, at least 33 states have HIV-specific criminal laws. Data from California, Florida, New York, and Texas nurses provided exemplars from different HIV-related criminal law approaches and the impact of those laws on nurses’ practices. Nurses who cared for patients who expressed fears or concerns about HIV criminalization or patients who had been arrested for HIV-related crimes were more likely to correctly identify the presence or absence of HIV-specific laws in the states where they practised, when compared to nurses who did not care for such patients. Lack of knowledge about HIV-related criminal laws may erode the nurse-patient relationship. Jurisdiction specific education should be created and offered to nurses in order to address this knowledge gap and protect the dignity of people living with HIV.
Saving Beauty: Renewing Moral Theology in Light of Hans Urs von Balthasar's Theological Aesthetics
Creators: name: MacDonald, Michel Gerard
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: moral theology
aesthetics

description: Responding to the call of Vatican II for a renewal of Catholic theology, this thesis makes an argument for the foundational role of beauty in moral theology. The thesis draws upon the theological aesthetics of Hans Urs von Balthasar to achieve this task. The introduction presents the statement of the problem, namely the prevailing legalism of Catholic moral theology prior to Vatican II. It also sets forth the state of the question. Here we see how the relationship between aesthetics and ethics has been neglected in recent times. Chapter one demonstrates the historical antecedents of the aesthetic-ethic connection in both ecclesial and ancient philosophical thought. The first chapter also sets forth the anthropological dimension of beauty for human action. Chapter two presents von Balthasar’s theological aesthetics. His insistence upon the role of beauty—which in theological terms is God’s glory—as the central theological method, necessarily has implications for moral theology. The third chapter elaborates the implications of von Balthasar’s theological aesthetics for moral theology. The aim of chapter three is not to set forth a ‘Balthasarian’ ethics, but to demonstrate how his theological aesthetics serves as a foundation for moral theology. The thesis is thus primarily meta-ethical. Finally, in chapter four we present some of the practical implications of a moral theological aesthetics by drawing upon Pope Francis’ Encyclical Laudato Si’.
A Mechanistic Approach Towards the Discovery of Catalytic Acylation Reactions
Creators: name: Zhang, Wanying
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Organometallic chemistry
Catalyst
Acylation
Aldol
Suzuki
Coupling

description: The development of new, efficient methods for the formation of carbon-carbon bonds using transition metal catalysis has broad applications in the field of organic chemistry and is the key to efficient chemical synthesis. Many efforts had been made to develop efficient ways to make these linkages particularly with the aid of metals such as Rh, Pd, Ni, Ru and Cu. Our group is primarily focused on exploring how these transition metals can activate typically inert functional groups, paving way to new synthetic routes to construct more complex molecules. Chapter 1 describes attempts that were conducted to achieve hydroacylation between an aldehyde and a non-conjugated alkene via a metal hydride intermediate. The use of RuHCl(CO)(PPh3)3 proved to be the most efficient catalyst for this transformation thus far. Mechanistic investigations were conducted to explore different possibilities to enable this transformation. This chapter also identifies a new self-aldol domino reaction, which consists of a self-aldol condensation of an aldehyde, followed by oxidation and decarbonylation giving rise to a ketone product. Finally, the use of a simple and direct method to access deuterated aldehydes using RuHCl(CO)(PPh3)3 as a catalyst and D2O as a deuterium source is outlined. Chapter 2 describes a novel Suzuki-Miyaura system that couples esters and boronic esters to form the corresponding ketone product. It was found that an NHC-based Pd catalyst is crucial in the transformation wherein it activates the C(acyl)-O bond of the ester. It is notable that this transformation takes place with the absence of decarbonylation. Reactivity under water in the presence of surfactants was also discovered. Results in aqueous media were demonstrated to be milder than in organic conditions, while achieving similar yields. This system was also applied to coupling of esters and anilines.
Additional file 1 of Drug screening targeting TREM2-TYROBP transmembrane binding
Creators: name: Cobas-Carreño, M.
name: Esteban-Martos, A.
name: Tomas-Gallardo, L.
name: Iribarren, I.
name: Gonzalez-Palma, L.
name: Rivera-Ramos, A.
name: Elena-Guerra, J.
name: Alarcon-Martin, E.
name: Ruiz, R.
name: Bravo, M. J.
name: Venero, J. L.
name: Morató, X.
name: Ruiz, A.
name: Royo, J. L.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Virology

description: Supplementary Material 1
The Role of Transmembrane Domain Helix-Helix Interactions in the Function of Pentameric Ligand-Gated Ion Channels
Creators: name: Therien, James Patrick Daniel
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: pLGIC
nAChR
GLIC
ELIC
Protein Structure and Function
Ion Channel

description: The pentameric ligand gated ion channel super family plays a central role in fast synaptic communication between neurons and at the neuromuscular junction. Extensive studies on the prototypic pLGIC, the Torpedo nicotinic acetylcholine receptor (nAChR) have revealed an exquisite lipid sensitivity, with the nAChR adopting a novel uncoupled conformation in membranes lacking activating anionic and neutral lipids. The lipid-exposed transmembrane alpha-helix, M4, in each homologous subunit likely acts as a lipid sensor. One model proposes that activating lipids promote M4 “binding” to the adjacent alpha-helices, M1 and M3, to enhance interactions between the M4 C-terminus and the Cys-loop of the agonist-binding domain, with such interactions promoting coupling between the agonist site and channel gate. The first part of my thesis indirectly tests this hypothesis by exploring the effects of membrane hydrophobic thickness on nAChR function. Specifically, I tested the hypothesis that thicker membranes, which should promote alignment of M4 parallel to M1/M3 and thus helix-helix interactions, favor a coupled conformation. Although I found that the nAChR is uncoupled in all membranes tested, regardless of hydrophobic thickness, thicker membranes promote transitions from uncoupled to ultimately the desensitized state over the minutes to hours time frame. In contrast to anionic lipids, which influence function primarily via a conformational selection mechanism, membrane hydrophobic thickness influences function via a kinetic mechanism - thick membranes lower the activation energy between uncoupled and coupled conformations to promote conformational transitions. In the second part of my thesis, I used the two prokaryotic homologs, GLIC and ELIC, to explore how amino acid interactions at the interface between M4 and M1/M3 influence channel activity. Alanine scanning mutagenesis of this interface shows that disruption of almost any interaction in GLIC leads to a loss of folding and/or function, while analogous mutations in ELIC typically lead to no change or produce gains in function. Sequence comparisons with other members of the pLGIC superfamily suggest that the transmembrane domains of GLIC and ELIC represent two distinct archetypes. Each archetype may strike a different balance between the need for strong M4 binding to M1/M3 to promote folding and pentamer assembly, and the need for weaker interactions that allow for greater conformational flexibility during function.
Risk Assessment of Dietary Lead (Pb), Cadmium (Cd), and Mercury (Hg) Exposure among First Nations People in Ontario, Canada - a Total Diet Study and Probabilistic Assessment
Creators: name: Juric, Amanda
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Risk Assessment
First Nations
Diet
Exposure Assessment
Total Diet Study

description: This thesis quantified risks of lead (Pb), cadmium (Cd), and mercury (Hg) in the diet of First Nations peoples residing on-reserve in the province of Ontario, Canada. Data was obtained from the 2011-2012 First Nations Food, Nutrition, and Environment Study (FNFNES) and Health Canada to construct total diet studies and probabilistic assessments. Results indicated that the majority of the population is at low risk of exceeding the reference values for these contaminants. Average exposures of Pb and Hg were higher than the general Canadian population (1.7 and 1.6 times greater, respectively), whereas Cd was 59% lower than the Canadian average. The upper percentiles of the population exposure distributions were characterized for contributing food items to assist risk management strategies. For cadmium exposures, smokers had elevated exposures compared to non-smokers. Women of childbearing age had lower dietary MeHg exposures than the total population and were largely below the reference value.
The Concept of Liturgical Reform in the Writings of Romano Guardini and Joseph Ratzinger / Pope Benedict XVI: A Comparative Analysis
Creators: name: Kurnyek, Robert
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: liturgical reform
Guardini
Ratzinger

description: This present work is a comparative analysis of the theologies of the liturgy of Romano Guardini and Joseph Ratzinger. The concept of liturgical reform forms the focus, because understanding this makes it possible to see very concretely how the two view liturgy, and in particular, theological and practical changes to the liturgy. With the help of this analysis, the reader will not only better understand their ideas of liturgy and liturgical reform, but will also be able to evaluate the preconceptions underlying Guardini and Ratzinger’s theologies of the liturgy. According to which the former represents the spirit of Vatican II, opposing what liturgy was before Vatican II, while the latter represents the thinking of the time before the Council. Interpreting their thought each in its own historical context, the thesis reveals the dissolution of this apparent opposition.
Health-related expectations of the chronically critically ill: a multi-perspective qualitative study
Creators: name: Howard, A. Fuchsia
name: Crowe, Sarah
name: Choroszewsk, Laura
name: Kovatch, Joe
name: Haynes, Adrianne Jansen
name: Ford, Joan
name: Beck, Scott
name: Haljan, Gregory
Publisher: name: BioMed Central
Year: 2021

description: Background: Those who survive critical illness only to become chronically critically ill (CCI) experience a high symptom burden, repeat episodes of illness exacerbation, communication barriers, and poor health outcomes. Yet, it is unclear how CCI individuals and their family understand their health and the importance of prognostic information following hospitalization. The research purpose was to examine expectations about health and disease prognosis of CCI residents in long-term care from the perspectives of the CCI themselves and their family members, as well as to describe healthcare provider (HCP) interpretations of, and reactions to, these health-related expectations. Methods: In this qualitative interpretive descriptive study, conducted in British Columbia, Canada, 38 semi-structured interviews were conducted (6 CCI residents, 11 family members, and 21 HCPs) and inductively analyzed using thematic and constant comparative techniques. Results: There was divergence in CCI resident, family and HCP expectations about health and the importance of disease prognosis, which contributed to conflict. CCI residents and family viewed conflict with HCPs in relation to their day-to-day care needs, while HCPs viewed this as arising from the unrealistically high expectations of residents and family. The CCI residents and family focussed on the importance of maintaining hope, and the HCPs highlighted the complexity of end-of-life decisions in conjunction with the high expectations and hopes of family. Conclusions: The emotional and ongoing process of formulating health-related expectations points to the need for future research to inform the development and/or adapting of existing communication, psychosocial and health services interventions to ease the burden experienced by those who are CCI.
Regulators of Adult Hippocampal Neurogenesis
Creators: name: Dhaliwal, Jagroop
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Adult Neurogenesis
Presenilin
Autophagy
Atg5
Doublecortin
PS1 and PS2
Retrovirus
Transgenic inducible

description: One mechanism of plasticity within the adult mammalian brain is the dynamic process of adult neurogenesis that is functionally important in physiological and pathological conditions. During this process, neurons develop from adult neural stem cells (NSCs) via intermediate neural progenitors (NPCs) through several processes including proliferation, survival, differentiation, migration and integration. Despite neurogenesis during development sharing these same processes, there is growing evidence highlighting unique mechanisms that regulate adult versus embryonic neurogenesis. The studies in this thesis test the cell-intrinsic function of genes that have defined roles in embryonic neurogenesis and undefined roles in adult hippocampal neurogenesis using a combination of transgenic inducible mice and in vivo retroviral techniques. The first study examines the microtubule associated protein Doublecortin (DCX), which is transiently expressed by NPCs and is critical for neuronal migration. Our results show that, in the context of adult hippocampal neurogenesis, DCX is not required for the survival or differentiation of the NPCs within the subgranular zone (SGZ). The second study examines the functional role of the autophagy-associated gene 5 (Atg5) which is critical for embryonic neurogenesis and survival. Our findings demonstrate that the intracellular recycling process of autophagy is active throughout maturation of adult hippocampal NPCs and that ablation of Atg5 produces a drastic reduction in NPC survival, without altering the neuronal fate of these cells. The third study examines the requirement of the familial-Alzheimer’s disease associated genes, presenilin 1 and presenilin 2 (PS1 & PS2), which are critical for embryonic NSC maintenance and differentiation. Similar to the findings with DCX, our results demonstrate that presenilins are dispensable for adult neurogenesis. Altogether, these studies add to the growing evidence suggesting differences in the regulation of adult versus embryonic neurogenesis, and highlight autophagy as a novel regulator of survival for adult generated granule neurons in the hippocampus.
Une lecture de la modernité par le biais de l’amour et du politique chez Arendt, Weil et Rougemont
Creators: name: Nguyen, Minh
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Hannah Arendt
Simone Weil
Denis de Rougemont
Amour
Érôs
Philia
Agapé
modernité
pluralité
commune mesure

description: Dans cette thèse de pensée politique, nous chercherons à renouer avec l’idéalité du projet politique moderne en pensant le lien qu’entretiennent amour et politique dans le cadre ce celui-ci. Au niveau du mouvement de la pensée politique, les modernes ont eu tendance à légitimer l’action politique à l’aune de cette norme transcendante qu’est la Raison. L’action politique était alors orientée vers une forme d’utopie. Or, avec le passage de la modernité à la postmodernité, le politique tend à être désormais orienté par une forme de rationalité technique fétichisée. Il est donc question pour nous de renouer avec la mission originelle de la pensée politique qui est de penser les finalités de l’être humain. Pour ce faire, nous allons examiner la nécessaire relation entre amour et politique. Trois penseurs politiques du 20e siècle, Hannah Arendt, Simone Weil et Denis de Rougemont, nous aideront à penser le lien entre amour et politique renouer avec l’idéalité moderne. Arendt nous permettra de penser l’amour comme un rapport à l’autre et au monde, qui est une condition de la pluralité. Weil nous permettra de penser l’amour comme une médiation qui institue une forme de subjectivité orientée vers un ailleurs transcendant. Quant à Rougemont, il nous permettra de penser l’amour comme un élément d’une une commune mesure moderne. Nous verrons que la rationalité technique à elle seule ne peut pas guider le politique, qu’elle doit aussi prendre en considération l’amour pour penser des normes définissant le commun. Nous verrons aussi que l’idéalité moderne est intimement liée à une conception de l’amour qui suppose une prise de distance.
Cloud Computing Service Discovery Framework for IaaS and PaaS Models
Creators: name: Firozbakht, Farzad
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Cloud
Computing

description: Cloud service discovery is a new challenge which requires a dedicated framework in order to approach it. Over the past few years, several methods and frameworks have been developed for cloud service discovery but they are mostly designed for all cloud computing models in general which are not optimal. The three cloud computing models are Infrastructure as a Service (IaaS), Platform as a Service (PaaS) and Software as a Service (SaaS), each computing model has its own set of resources. Having one single discovery framework for all three is not very efficient and the implementation of such a framework is complex with lots of overhead. The existing frameworks for cloud service discovery are mostly semantic-based and there are a few syntax-based frameworks that are using the filter by Attribute method as their solution. This research proposes a cloud service discovery framework focusing on IaaS and PaaS cloud computing models. Our framework is using a syntax-based query engine at its core and uses Extensible Markup Language (XML) for storing cloud service information. We eventually test the framework from the user point of view with IaaS and PaaS cloud services from real cloud service providers. Such a framework could be a good solution for IaaS and PaaS since it is accurate enough for service discovery and easy to update.
The Meaning of Suffering: Shaping Conceptualizations of Assisted-Death
Creators: name: Przybylak-Brouillard, Antoine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Assisted-Death
Suffering
Right to die
Belgium
Quebec
Euthanasia

description: In recent years the right to die has emerged from the fringes as a global movement - locally tailored - advocating for patient access to medically assisted-death. Although proposed and actualized models of assisted-death vary in method and level of accessibility, a majority of right to die advocates are motivated by a belief that suffering can at times be “unnecessary”. Based on an overview of the anthropology of suffering and fieldwork in Quebec, Ontario, and Belgium, my research focuses on right to die advocates’ conceptualization of suffering in relation to assisted-death and on how their understanding suffering shapes their views on when assisteddeath should be permitted. I argue that those supporting assisted-death are brought in a form of solidarity through the belief that at times suffering is meaningless and devoid of deeper significance.
Eugoa hainanensis Fang 2000
Creators: name: Volynkin, Anton V.
name: Bucsek, Karol
name: Černý, Karel
name: Saldaitis, Aidas
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Erebidae
Eugoa
Eugoa hainanensis

description: Eugoa hainanensis Fang, 2000
(Figs 6, 12)
 Eugoa hainanensis Fang, 2000, Fauna Sinica. Insecta 19: 63, 536, text fig. 37, pl. I, fig. 20 (Type locality: “ Hainan Jianfengling”).
 = Eugoa simonae Bucsek, 2008, Entomofauna 29 (26): 427, figs 15, 16, 75, 76 (Type locality: “ Cambodia, Kirirom Nat. Park, 780 m, N11°21 "23”, E104°4 "38”).
 Type material examined. Holotype: male, “ Cambodia, Kirirom Nat.Park, 780 m, N 11º21 "23"", E 104º4 "38"", 2.–17.I.2000, leg. M. & S. Murzin (Coll. MWM / ZSM). Paratypes: 1 female, same data as in the holotype (Coll. MWM / ZSM); 1 male, S India, Tamil Nadu, Kalkao Wildlife Sanctuary, Manimtar-Kodear, 1300 m, 8°19"N, 77°26"E, 8.IV.1997, leg. Sinjaev & Schintlmeister (Coll. MWM / ZSM); 1 male, Nepal, Mechi, Taplejung area, Tamur valley, 4 km N Dobhan, 800 m, 87°40"E, 27°22"N, 22.X.1996, leg. Gy. M. László & G. Ronkay (Coll. MWM / ZSM); 1 male, N Thailand, Mae Hong Son, 10 km E Khun Yuam, 950 m, N18º47 "10"", E98º3 "4"", forest border, 1.V.2006, leg. Karel Černý (Coll. CKB); 1 female, Thailand, Mt. Doi Phahompok, 14 km NW of Fang, 1700 m, 16.X.2000, leg. local collector (Coll. MWM / ZSM); 1 female, SW Thailand, Chumphon prov., Pa Toh distr., Ban Lang Tang, 162 m, N9º46.5 ", E98º46.59 ", 21.XI.2006, leg. Karel Černý (Coll. CKB).
 Other material examined: 3 males, 03–16.VIII.2016, South Laos, Champasak prov., 27 km ENE of Pakse, near Tad Fane waterfall, N15°11'01.1'' E106°07'40.5'', 950 m, border of primary forest, A.V. Volynkin & M.S. Ivanova leg., slides AV 3106m, AV 3113m, AV 3115m (Coll. CAV).
 Distribution. The species is widespread in India, Nepal, SE China (Hainan Isl.), Thailand, Cambodia (Fang, 2000; Bucsek, 2008, Černý and Pinratana, 2009) and Laos.
description: Published as part of Volynkin, Anton V., Bucsek, Karol, Černý, Karel & Saldaitis, Aidas, 2018, On the taxonomy of the genus Eugoa Walker, 1858, with descriptions of two new species from Laos and Vietnam (Lepidoptera, Erebidae, Arctiinae, Lithosiini), pp. 102-109 in Ecologica Montenegrina 19 on page 108, DOI: 10.37828/em.2018.19.11, http://zenodo.org/record/13360118
AlGaAs Microring Resonators for All-Optical Signal Processing
Creators: name: Gomes, Prova Christina
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Microring resonator
All-optical signal processing
Four-wave mixing
AlGaAs

description: Photonic integration and all-optical signal processing are promising solutions to the increasing demand for high-bandwidth and high-speed communication systems. III-V semiconductor materials, specially AlGaAs, have shown potentials for photonic integration and efficient nonlinear processes due to their low nonlinear absorption, flexibility at controlling the refractive index, and mature fabrication technology. In this thesis, we report the designs of AlGaAs microring resonators optimized for efficient four-wave mixing. Four-wave mixing (FWM) is a nonlinear optical phenomenon which can be used to realize many optical signal processing operations such as optical wavelength conversion and optical time division multiplexing and demultiplexing. Our designed AlGaAs microring resonators are expected to have good optical confinement, transmission characteristics, and efficient coupling between the ring and waveguide. Here we also present our fabrication efforts to fabricate the microring resonators device and the insights gained in the process. The microring resonators devices have a potential to be used in optical communication networks for all-optical signal processing operations.
Additional file 1 of Barriers and facilitators to self-management in people with back-related leg pain: a qualitative secondary analysis
Creators: name: Ziegler, Anna-Marie L.
name: Thorpe, Don
name: Kennedy, Douglas
name: Schulz, Craig
name: Salsbury, Stacie A.
name: Bronfort, Gert
name: Evans, Roni
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1
Event modelling for policymakers and valuation analysts in disruptive innovation markets: digital download strategies for Radiohead's 'In Rainbows' and Nine Inch Nails' 'The Slip'
Creators: name: Burns, Alex
Publisher: name: Swinburne
Year: 2024

description: Using a 'paired' study, this paper examines why the musicians Radiohead and Nine Inch Nails pursued digital download strategies for their albums In Rainbows (2007) and The Slip (2008). Three explanations at the time (Web 2.0, Chris Anderson's Freeconomics, Scott Anthony's Disruptive Innovation Theory) are evaluated. The paper sketches Disruptive Innovation Markets as a conceptual framework and Disruptive Information Revelation as a process of inductive logic for analysts. The 'paired' study finds other variables not discussed: career arcs, major label contracts, musician control over marketing and risk management, and digital media as a new option during negotiations for new recording deals. Significantly, the three earlier explanations overlooked the musicians' negative experiences after Terra Firma Capital Partners and Vivendi SA acquired their major labels EMI and UMG. Further research opportunities and implications for journalists, policymakers and valuation analysts are discussed.
Localization and Terminometrics: Measuring the Impact of User Involvement on Terminology
Creators: name: Bilgen, Baris
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: localization
terminology
terminometrics
open source
software
online collaboration
corpus analysis
term formation
ubuntu

description: Online collaborative translation has received increased attention from Translation Studies, mostly with a focus on explaining the various models it exhibits and the factors that shape these models. This study takes a new perspective on this phenomenon by focusing on its outcome through the lens of terminology. A terminometric analysis is carried out on the terminology used in the discussions of Francophone users on online forums of the Ubuntu-Québec open-source software community. The implantation of terms used in the forums and those stored in a selection of major term banks is examined with the objective of identifying potential correlations between term implantation and term formation patterns. The examination indicates that most terms formed through the use and modification of existing linguistic resources have higher implantation rates than terms formed through the creation of new lexical items. A new avenue of terminometric research is introduced by shifting the focus from the institution to the community, aligning with the global shift in content production and distribution. The study provides insight into online collaboration in the context of localization and points out correlations between term formation patterns and term implantation. These observations can mark a starting point for terminological decision-making that is informed by user behaviour and may thus improve the reception of localized content by adapting to users' terminological expectations.
Normas y plantillas revista Ciencia e Ingeniería vigentes 2023
Creators: name: Ciencia e Ingeniería
Publisher: name: Universidad de La Guajira
Year: 2023
Subjects: guía de autores
normas de publicación
declaraciones y derechos de publicación
publicar

description: Estos son documentos para guiar a los autores que publiquen en la revista Ciencia e Ingeniería de la Universidad de La Guajira, Riohacha, Colombia.
Flow Obstruction Effects on Heat Transfer in Channels at Supercritical and High Subcritical Pressures
Creators: name: Eter, Ahmad
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Supercritical and high subcritical pressures
Convective heat transfer
Experimental data
Carbon dioxide
Heat transfer deterioration
Rod bundle and tube test sections
Wire wrap and grid spacers
Blunt obstacles
Adverse impact of flow obstacles on heat transfer
Approximate model of 3D heat conduction in rod bundles

description: The objective of this thesis research is to improve our understanding of the flow obstacle effect on heat transfer at supercritical and high subcritical pressures by experimentally studying the effect of different obstacles on heat transfer in two vertical upward-flow test sections: a 3-rod bundle and an 8 mm ID tube. The heat transfer measurements cover the region of interest of the Canadian Super-critical Water Cooled Reactor (SCWR). A thorough analysis of the obstacle effect on supercritical heat transfer (SCHT) was performed. In the 3-rod bundle, two types of obstacles were employed: wire wraps and low-impact grid spacers. Wire wraps were found to be more effective than grid spacers to enhance the SCHT. In the tubular test section, obstacles appeared to suppress the heat transfer deterioration (HTD) or decrease its severity; obstacles also generally enhanced the SCHT both in the liquid-like and the gas- like region. The experiment in the tubular test section revealed that, at certain flow conditions (low mass flux, low inlet subcooling), flow obstacles can have an adverse impact on the SCHT. A criterion to predict the onset of this adverse effect was developed. At high subcritical pressures, obstacles increased the CHF and reduced the maximum post-CHF temperature. A comparison of the experimental data with prediction methods for the SCHT, single phase heat transfer, CHF and post-dryout heat transfer was performed. Lastly, a new correlation to predict the enhancement in SCHT due to obstacles was developed for heat transfer in the liquid-like and gas-like regions.
Negotiating Life Within the City: Social Geographies and Lived Experiences of Urban Metis Peoples in Ottawa
Creators: name: Dumas, Daniel
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Indigenous peoples
Metis
Decolonization
Urban

description: The majority of Indigenous peoples in Canada are now living in urban centres. Following the publication of the Final Report of the Royal Commission on Aboriginal Peoples in 1996, academics and policy makers were encouraged to further research the heterogeneous experiences and realities of urban Indigenous peoples living in Canadian cities. This thesis responds to this call and seeks to explore the social geographies and lived experiences of urban Metis peoples, a segment of the urban Indigenous population that has to date been largely left out of the literature. This work relates specifically to Metis living in Ottawa, representing the first study of its kind in eastern Canada. Although Ottawa is not a traditional Metis community and is located outside of the traditional Metis Homeland, the city does represent an important Metis meeting place and space where various understandings of Metis identity from across the country come into contact with one another. The ways in which urban Metis identities are formed and maintained, the movement and strategies Metis peoples utilize to create a sense of place and home, and the ways in which individuals and the community at large come into contact with power at the municipal level are explored at length. Utilizing Henri Lefevbre and Iris Marion Young’s concepts of right to the city and unassimilated otherness, this thesis argues that urban Metis peoples in Ottawa merit greater recognition primarily through the creation of a permanent fixture, such as a Metis house, within the city’s urban landscape.
Optimising the provision of preconception care in Australian general practice: leveraging systems and providers
Creators: name: Withanage, Nishadi Nethmini
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 420304
subject: General practice

description: Preconception care (PCC) includes interventions like dietary changes, counselling, and programs to reduce smoking and alcohol consumption before conception. These measures reduce pregnancy complications and improve maternal and child health. In Australia, general practices are ideal for providing PCC but don't do so routinely. My PhD project aims to explore the potential use of electronic medical records in general practices to identify and invite reproductive-aged women with preconception risk factors to benefit from PCC. My project involved a systematic review, developing an audit tool, a clinical audit of electronic medical records, and interviews with PCC providers in general practice (general practitioners and practice nurses) and reproductive-aged women.
A Novel Role for SLK in Transforming Growth Factor-Beta-Mediated Epithelial-to-Mesenchymal Transition
Creators: name: Conway, Jillian
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Epithelial-to-mesenchymal transition
Ste20-like kinase
Transforming Growth Factor-Beta

description: In the late stages of cancer, tumors acquire the ability to spread throughout the body and invade distant tissues in a process called metastasis. Studies have shown that metastasis is responsible for 90% of all cancer-related deaths, making this an important field of study. In breast cancers, 30% of patients overexpress the HER2 oncoprotein, causing a more invasive and metastatic disease. Invasion can be stimulated in vitro using the soluble ligand transforming growth factor-β (TGFβ) to induce a process called EMT (epithelial-to-mesenchymal transition), where epithelial cells transition into a migratory phenotype through cell-cell junction breakdown. SLK is a Ste20-like kinase that has been linked to many processes, including cell migration and signaling downstream of the HER2 receptor complex. Here we show that the cellular migration and invasion of TGFβ-treated normal mammary epithelial cells is significantly impaired in the absence of SLK. Additionally, immunofluorescence analyses demonstrate that SLK knockdown conditions decrease a cell’s ability to progress through EMT due to the visible staining of epithelial markers. We find that SLK-depleted cultures express significantly lower levels of Snail1,and fibronectin mRNA levels following TGF-β treatment. Surprisingly, our data demonstrates that SLK kinase activity is not activated downstream of TGF-β stimulation, and that a kinase-dead SLK rescues Snail1 mRNA expression levels. Together these data suggest that SLK plays a novel role in TGFβ-induced epithelial-to-mesenchymal transition in a kinase activity-independent manner.
Additional file 1 of Greenness, blueness, and whiteness evaluation of a quantitative nuclear magnetic resonance procedure for concurrent assay of aspirin and omeprazole in their single and fixed-dose combined tablets
Creators: name: El-Masry, Amal A.
name: Zeid, Abdallah M.
name: Abdallah, Nora A.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Supplementary material 1
Additional file 2 of Barriers and facilitators to self-management in people with back-related leg pain: a qualitative secondary analysis
Creators: name: Ziegler, Anna-Marie L.
name: Thorpe, Don
name: Kennedy, Douglas
name: Schulz, Craig
name: Salsbury, Stacie A.
name: Bronfort, Gert
name: Evans, Roni
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2
Intermolecular [3+2] Cycloadditions of Imino-isocyanates to Access β-Amino Carbonyl Compounds
Creators: name: Bongers, Amanda L.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: isocyanate
aminocarbonylation
amino-isocyanate
imino-isocyanate
[3+2] cycloaddition
azomethine imine
β-amino carbonyl
alkene

description: In modern synthetic organic chemistry, chemists are driven to develop efficient methods for important C-C and C-N bond formation reactions. The challenge lies with establishing new uses for readily available substrates. In this regard, the synthesis of β-aminocarbonyl compounds from alkenes remains a long-standing challenge. Innovation in reaction discovery often requires finding new reagents, or rare reagents with underappreciated value in synthesis. In Chapter 1, N-isocyanates and other heterocumulenes are introduced as versatile amphoteric reagents. Their amphoteric properties are valuable in the discovery of new synthetic approaches, especially in cycloaddition reactions. While C-isocyanates are bulk industrial chemicals, the formation and reactivity of N-isocyanates remains underexplored. Chapter 2 describes the development of reactivity with rare imino-isocyanates. This includes methods to access the reagent in situ with a blocking group approach, and the establishment of intermolecular cycloaddition reactivity with a variety of alkenes. This stereospecific reaction provides complex N,N’-cyclic azomethine imines, and enables access to β-aminocarbonyl compounds from alkenes. β-Amino amides and esters, pyrazolidinones, and pyrazolones were accessed by reductive derivatization of the aminocarbonylation products. Exploration into the limits of this reactivity gave insight into fundamental properties of imino-isocyanates. This includes the first detection of imino-isocyanates by IR spectroscopy. A kinetic resolution of the azomethine imines obtained from this alkene aminocarbonylation reaction was then developed, which gave access to enantioenriched β-amino carbonyl compounds (Chapter 3). This was accomplished by Brønsted acid catalysed reduction, with a selectivity factor of 13-43. This was the first example of the enantioselective reduction of azomethine imines, and represents a new activation mode for reactions of N,N’-cyclic azomethine imines. Using this reductive method, both enantiomers of the β-amino amide could be obtained from a racemic azomethine imine in ≥ 97% ee. The discovery of new reactivity of imino-isocyanates with imines in described in Chapter 4, which allowed the synthesis of eight new azomethine imines with the triazolone core. Our initial scope studies revealed different trends with imines than with alkenes, including increased reactivity, which led to investigation of the mechanism of this reaction. In addition, this was shown to be a valuable new approach for the synthesis of triazolones from imines.
Sustainable Biosynthesis of Antioxidants from Koji Rice Fermented with Aspergillus flavus Using Microwave-Assisted Extraction
Creators: name: Al Rubaiy, Hassan Hadi Mehdi
name: Altemimi, Ammar
name: Al Rikabi, Ali Khudair Jaber
name: Lakhssassi, Naoufal
name: Pratap-Singh, Anubhav
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2021

description: The present study proposes microwave-assisted extraction as a sustainable technique for the biosynthesis of bioactive compounds from rice fermented with Aspergillus flavus (koji). First, fermentation conditions (i.e., pH from 3–12, five temperatures from 20–40 °C, and four culture-fermentation media viz. wheat, wheat bran, malt and rice) were optimized for producing microbial bioactive compounds. Microwave extraction was performed at 2450 MHz and 500 W for 20, 30, and 40 s with seven solvents (distilled water, ethyl acetate, hexane, ethanol, chloroform, diethyl ether, and methanol). The obtained results revealed that ethyl acetate is the most appropriate solvent for extraction. Effects of this ethyl acetate extract were compared with a commercial synthetic antioxidant. Antioxidant properties were enhanced by preventing the oxidation of the linoleic acid (C18H32O2) with an inhibition rate (antioxidant efficacy) of 73.13%. Notably, the ferrous ion binding ability was marginally lower when compared to the disodium salt of ethylenediaminetetraacetic acid (EDTA). Additionally, the obtained total content of phenolic compounds in the ethyl acetate extract of fermented rice (koji) by Aspergillus flavus was 232.11 mg based on gallic acid/mL. Antioxidant compounds in the ethyl acetate extract of fermented rice showed stability under neutral conditions, as well as at high temperatures reaching 185 °C during 2 h, but were unstable under acidic and alkaline conditions. The results demonstrate the efficacy of novel microwave-assisted extraction technique for accelerating antioxidant production during rice fermentation.
Novel Functions for the RNA-binding Protein Staufen1 in Skeletal Muscle Biology and Disease
Creators: name: Crawford Parks, Tara
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: RNA-binding Proteins
Staufen1
Skeletal Muscle
Myotonic Dystrophy Type I
Rhabdomyosarcoma
Alternative Splicing

description: Over the past decade several converging lines of evidence have highlighted the importance of post-transcriptional events in skeletal muscle. This level of regulation is controlled by multi-functional RNA-binding proteins and trans-acting factors. In fact, several RNA-binding proteins are implicated in neuromuscular disorders including myotonic dystrophy type I, spinal muscular atrophy and amyotrophic lateral sclerosis. Therefore, it is necessary to examine the impact of RNA-binding proteins during skeletal muscle development and plasticity in order to understand the consequences linked to their misregulation in disease. Here, we focused on the RNA-binding protein Staufen1, which assumes multiple roles in both skeletal muscle and neurons. We previously demonstrated that Staufen1 is regulated during myogenic differentiation and that its expression is increased in denervated and in myotonic dystrophy type I skeletal muscles. The increased expression of Staufen1 initially appeared beneficial for DM1 since further elevating Staufen1 levels rescued key hallmarks of the disease. However, based on the multi-functional nature of Staufen1, we hypothesized that Staufen1 acts as a disease modifier in DM1. To test this, we investigated the roles of Staufen1 in skeletal muscle biology and their implications for disease. Our data demonstrated that Staufen1 is required during the early stages of muscle development, however its expression must remain low in postnatal skeletal muscle. Interestingly, the overexpression of Staufen1 impaired myogenesis through the regulation of c-myc translation. Since the function of c-myc in oncogenesis is well described, we investigated the role of Staufen1 in cancer biology. In particular, we determined novel functions of Staufen1 in rhabdomyosarcoma tumorigenesis, thus providing the first direct evidence for Staufen1’s involvement in cancer. Moreover, based on Staufen1’s role in myogenic differentiation and in myotonic dystrophy type I, we generated muscle-specific transgenic mice to examine the impact of sustained Staufen1 expression in postnatal skeletal muscle. Staufen1 transgenic mice developed a myopathy characterized by histological and functional abnormalities via atrogene induction and the regulation of PTEN mRNAs. In parallel, we further investigated Staufen1-regulated alternative splicing and our data demonstrated that Staufen1 regulates multiple alternative splicing events in normal and myotonic dystrophy type I skeletal muscles, both beneficial and detrimental for the pathology. Collectively, these findings uncover several novel functions of Staufen1 in skeletal muscle biology and highlight Staufen1’s role as a disease modifier in DM1.