cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Genomic evolution and virulence association of Clostridioides difficile sequence type 37 (ribotype 017) in China
Creators: name: Xu, Xingxing
name: Luo, Yuo
name: Chen, Huan
name: Song, Xiaojun
name: Bian, Qiao
name: Wang, Xianjun
name: Liang, Qian
name: Zhao, Jianhong
name: Li, Chunhui
name: Song, Guangzhong
name: Yang, Jun
name: Sun, Lingli
name: Jiang, Jianmin
name: Wang, Huanying
name: Zhu, Bo
name: Ye, Guangyong
name: Chen, Liang
name: Tang, Yi-Wei
name: Jin, Dazhi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Clostridioides difficile sequence type (ST) 37 (ribotype 017) is one of the most prevalent genotypes circulating in China. However, its genomic evolution and virulence determinants were rarely explored. Whole-genome sequencing, phylogeographic and phylogenetic analyses were conducted for C. difficile ST37 isolates. The 325 ST37 genomes from six continents, including North America (n = 66), South America (n = 4), Oceania (n = 7), Africa (n = 9), Europe (n = 138) and Asia (n = 101), were clustered into six major lineages, with region-dependent distributions, harbouring an array of antibiotic-resistance genes. The ST37 strains from China were divided into four distinct sublineages, showing five importation times and international sources. Isolates associated with severe infections exhibited significantly higher toxin productions, tcdB mRNA levels, and sporulation capacities (P < 0.001). Kyoto Encyclopedia of Genes and Genomes analysis showed 10 metabolic pathways were significantly enriched in the mutations among isolates associated with severe CDI (P < 0.05). Gene mutations in glycometabolism, amino acid metabolism and biosynthesis virtually causing instability in protein activity were correlated positively to the transcription of tcdR and negatively to the expression of toxin repressor genes, ccpA and codY. In summary, our study firstly presented genomic insights into genetic characteristics and virulence association of C. difficile ST37 in China. Gene mutations in certain important metabolic pathways are associated with severe symptoms and correlated with higher virulence in C. difficile ST37 isolates.
Wiedergewinnung verlorener Schrift und Analyse der Tintenzusammensetzung der beglaubigten Kopie der Handelsprivilegien Hamburgs, Threse B 15 a (von 14.Juli 1482), Bibliothek des Staatsarchives, Hamburg
Creators: name: Shevchuk, Ivan
name: Bonnerot, Olivier
name: Brockmann, Christian
name: Hahn, Oliver
Publisher: name: Universität Hamburg
Year: 2021
Subjects: CSMC
SFB950
Manuscript
Written Artefacts
Artefact Profiling
BAM
Bibliothek des Staatsarchives, Hamburg
Z01
Z02
Multispectral Imaging (MSI)
X-Ray Fluorescence (XRF)
Megavision E7
Bruker ARTAX
Parchment
Iron Gall Ink
Damaged Writing
Ink Analysis
Medieval
15th century CE
European
Hamburg
Urkunde

description: Conference poster. Conference: "Archäometrie und Denkmalpflege 2018" DESY, Hamburg Multispectral Imaging and X-Ray Fluorescence in Ink Analysis and recovery of lost writing, Threse B 15 a (von 14.Juli 1482), Bibliothek des Staatsarchives, Hamburg An authentic copy of a certificate of trade privileges issued by the Kaiser Friedrich the third on 14th of July 1482 to the mayor and council of Hamburg, was analyzed. The certificate, which is stored at the state archive in Hamburg, regards regulations for shipping commercial goods on the Elbe river. This document confirms that no goods like rye, wheat, barley and other grains, as well as wine and beer, could be shipped past Hamburg’s harbor and that they had to be unloaded and traded in Hamburg instead. It also withdraws the previously granted trade privilege to Lord of Barby, also located on the Elbe river, south of Magdeburg, to ship goods past Hamburg’s harbor without paying a customs fee. Unfortunately, the legibility of the certificate of privileges is impeded locally due to severe mold damage, as the document was stored in a cold humid room. We present complementary results of ink investigation and text recovery performed by MSI and XRF techniques. Supplementary data can be found here: Multispectral Imaging Data X-Ray Fluorescence Data
description: The research for this project was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) within the Sonderforschungsbereich 950 (SFB 950). The research was conducted within the scope of the Centre for the Study of Manuscript Cultures (CSMC) at Universität Hamburg in collaboration with the Bundesanstalt für Materialforschung und -prüfung (BAM).
description: {"references": ["10.3204/DESY-PROC-2018-01", "https://www.researchgate.net/publication/343230234_MULTISPECTRAL_IMAGING_AND_X-RAY_FLUORESCENCE_IN_INK_ANALYSIS_AND_RECOVERY_OF_LOST_WRITING"]}
Tunneling spectroscopy of localized states of $\mathrm{WS}_2$ barriers in vertical van der Waals heterostructures
Creators: name: Papadopoulos, Nikos
name: Gehring, Pascal
name: Watanabe, Kenji
name: Taniguchi, Takashi
name: van der Zant, Herre S. J.
name: Steele, Gary A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: In transition metal dichalcogenides, defects have been found to play an important role, affecting doping, spin-valley relaxation dynamics, and assisting in proximity effects of spin-orbit coupling. Here, we study localized states in $\mathrm{WS}_2$ and how they affect tunneling through van der Waals heterostructures of h-BN/graphene/$\mathrm{WS}_2$/metal. The obtained conductance maps as a function of bias and gate voltage reveal single-electron transistor behavior (Coulomb blockade) with a rich set of transport features including excited states and negative differential resistance regimes. Applying a perpendicular magnetic field, we observe a shift in the energies of the quantum levels and information about the orbital magnetic moment of the localized states is extracted.
Probability theory applied to genetic populations
Creators: name: Watterson, Geoffrey Anton
Publisher: name: The Australian National University
Year: 1960
Subjects: Biometry
Probabilities
Genetics Mathematical models

description: 209 leaves
description: This thesis is concerned with certain aspects of the genetic behaviour of a zoological or botanical population. Broadly speaking, the models used here to describe populations are 'natural', in the sense that they subject the individuals to mainly random influences, as opposed to the controlled environments such as poultry and many vegetable crops. The aim is to discover the evolutionary significance of these random influences by the application of probability theory; an analysis is made of the possible states of the population after a considerable number of generations has elapsed from some initial instant.
Search for correlations of high-energy neutrinos and ultra-high-energy cosmic rays
Creators: name: Schumacher, Lisa
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The IceCube Neutrino Observatory has recently found compelling evidence for a particular blazar producing high-energy neutrinos and $\mathrm{PeV}$ cosmic rays, however the sources of cosmic rays above several $\mathrm{EeV}$ remain unidentified. It is believed that the same environments that accelerate ultra-high-energy cosmic rays (UHECRs) also produce high-energy neutrinos via hadronic interactions of lower-energy cosmic rays. Two out of three joint analyses of the IceCube Neutrino Observatory, the Pierre Auger Observatory and the Telescope Array yielded hints for a possible directional correlation of high-energy neutrinos and UHECRs. These hints however became less significant with more data. Recently, an improved analysis with an approach complementary to the other analyses has been developed. This analysis searches for neutrino point sources in the vicinity of UHECRs with search windows estimated from deflections by galactic magnetic fields. We present this new analysis method for searching common hadronic sources, additionally including neutrino data measured by ANTARES in order to increase the sensitivity to possible correlations in the Southern Hemisphere.
description: Proceeding for the VLVnT-2018 Conference, 4 pages, 2 figures
Dynamical description of the breakup of one-neutron halo nuclei 11Be and 19C
Creators: name: Typel, S.
name: Shyam, R.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We investigate the breakup of the one-neutron halo nuclei 11Be and 19C within a dynamical model of the continuum excitation of the projectile. The time evolution of the projectile in coordinate space is described by solving the three-dimensional time dependent Schroedinger equation, treating the projectile-target (both Coulomb and nuclear) interaction as a time dependent external perturbation. The pure Coulomb breakup dominates the relative energy spectra of the fragments in the peak region, while the nuclear breakup is important at higher relative energies. The coherent sum of the two contributions provides a good overall description of the experimental spectra. Cross sections of the first order perturbation theory are derived as a limit of our dynamical model. The dynamical effects are found to be of the order of 10-15% for the beam energies in the range of 60 - 80 MeV/nucleon. A comparison of our results with those of a post form distorted wave Born approximation shows that the magnitudes of the higher order effects are dependent on the theoretical model.
description: 15 pages, ReVTeX, 5 figures, typos corrected, accepted for publication in Physical Review C
Adsorptive potential of Zea mays tassel activated carbon towards the removal of metformin hydrochloride from pharmaceutical effluent
Creators: name: Menala Kalumpha
name: Upenyu Guyo
name: Ngceboyakwethu P. Zinyama
name: Felistus Muhle Vakira
name: Benias C. Nyamunda
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 60506 Virology

description: In the present study, Zea mays tassel which is a zero-value agricultural waste was used to produce a low-cost activated carbon using phosphoric acid as the activating agent. The prepared Z. mays tassel activated carbon (ZMTAC) was characterized by Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The adsorbent was applied for adsorption of an emerging contaminant, metformin hydrochloride (MH) from pharmaceutical effluent. The effects of solution pH, contact time, adsorbent dosage, and initial MH concentration and their interactions were investigated using a response surface methodology following a central composite experimental design (CCD). The optimum experimental conditions were as follows: pH 9.5, contact time 67.50 min, dosage 0.5750 g, and MH concentration 152.50 mg/L. The isotherm data followed Langmuir isotherm model (R2 = 0.979; sum of square deviation, SSD = 0.321). The saturation adsorption capacity of ZMTAC was 44.84 mg/g at 20 °C. MH adsorption process followed pseudo-second-order kinetics (higher R2 and smaller SSD values). The thermodynamic properties obtained showed that the adsorption process was feasible, endothermic and spontaneous. Consequently, the study demonstrated that Z. mays tassel is a potential precursor for preparation of adsorbents for the removal of the MH from pharmaceutical effluent.
Anthaxia (Haplanthaxia) viridifrons Gory 1841
Creators: name: Carlton, Christopher E.
name: MacRae, Ted C.
name: Tishechkin, Alexey K.
name: Bayless, Victoria L.
name: Johnson, Wood
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Buprestidae
Anthaxia
Anthaxia viridifrons

description: 43. Anthaxia (Haplanthaxia) viridifrons Gory,
 1841
 Parish records (n = 15): Bossier, Catahoula, East Baton Rouge, Grant, St. Landry, St. Martin, and Tensas Parishes (FSCA, LSAM, MEM).
 Potential larval hosts in Louisiana: Amelanchier arborea, Carya cordiformis, Carya glabra, Carya illinoinensis, Carya ovata, Carya tomentosa, Morus sp., Ulmus americana, Ulmus crassifolia, and Ulmus rubra; records of larvae utilizing Salix spp. and Vitis spp. probably not this buprestid species (MacRae 2006). Adults reported also on Acer saccharum, Asimina triloba (L.) Dunal, Carya cordiformis, Cercis canadensis, Crataegus sp., Fraxinus americana L., Gleditsia triacanthos, Juglans nigra, Malus sp., Quercus alba, Quercus rubra, Rubus sp., and Ulmus alata Michx.
Collection date range: 8 April–12 May.
Comments: Collected at light and boll weevil pheromone traps.
Tribe Xenorhipidini
description: Published as part of Carlton, Christopher E., MacRae, Ted C., Tishechkin, Alexey K., Bayless, Victoria L. & Johnson, Wood, 2018, Annotated Checklist of the Buprestidae (Coleoptera) from Louisiana, pp. 351-367 in The Coleopterists Bulletin 72 (2) on page 357, DOI: 10.1649/0010-065X-72.2.351, http://zenodo.org/record/5382706
A Relativistic Extension of Event-Enhanced Quantum Theory
Creators: name: Ruschhaupt, Andreas
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, we develop a formalism describing in a relativistic way a system which consists of a classical and a quantum part being coupled. The formalism models one particle with spin 1/2 and it is a possible relativistic extension of the Event-Enhanced Quantum Theory. We postulate a covariant algorithm which plays the role of the standard reduction postulate in non-relativistic quantum mechanics. Furthermore, we present an algorithm to simulate detections of the particle.
description: 17 pages, Latex
Practical Solutions for Fault-Tolerance in Connected and Autonomous Vehicles (CAVs)
Creators: name: Bhat, Anand
Publisher: name: Carnegie Mellon University
Year: 2019
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: With advances in sensing, machine learning, and computing systems, various semiautonomous and autonomous driving applications have become feasible. This has resulted
in a dramatic increase in the amount and complexity of computational resources needed in vehicles. Tasks such as perceiving the environment using sensors like lidars,
radars, and cameras, fusing data from these sensors to create a road-world model, route planning, and modeling behaviors, are all computationally intensive and safetycritical. Conventionally, system reliability in safety-critical applications including aviation
is achieved by replicating hardware and running multiple instances of the same software on different pieces of hardware. Often, a voting mechanism is used to generate
the output, and measures are taken in the system design to ensure that hardware components fail independently. However, this approach is extremely inefficient in terms of cost, weight, space and power, especially for the automotive industry. High automation levels
impose more stringent fault-tolerance requirements in terms of the number of tasks that need redundancies (standbys), as well the number of failures that are required to be
tolerated for each task (i.e., the number of standbys for each task). Also, the operational design domain (ODD) of the automated vehicle has a significant impact on the fault-tolerance requirements. This motivates the need for adaptive cost-optimized software fault-tolerance solutions to reduce overall resource utilization. This dissertation aims to
achieve this objective in the context of resource-constrained fault-tolerant autonomous driving applications by considering a comprehensive set of system-level design considerations
together. First we present a family of optimal and sub-optimal harmonic search algorithms and heuristics for selecting task execution parameters. We then present a
framework to derive replication parameters for a given task set and a family of heuristics to allocate tasks to computing nodes while optimizing CPU resource utilization. We
next design and implement our software architectures to support fault-tolerant execution on popular automotive platforms and demonstrate that our primitives are practical through experimental evaluations. Finally, we also present the tools and methodologies we use to test and verify the safe operation of an autonomous driving vehicle.
Exploring the molecular insights of intrinsically disordered mitochondrial intermembrane protein in its unbound and substrate-bound state
Creators: name: S. Mathangi
name: H. V. Arvind Chandrasekharan
name: L. Ramya
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: Intrinsically disordered proteins (IDPs) are a major class of proteins that remain biologically active despite lacking a proper tertiary structure. They can adopt a fold when bound with the substrate. Mitochondrial Intermembrane space import and assembly protein 40 (Mia40) come under the category of membrane IDP. This protein plays a vital role in the import, oxidation, and folding of other mitochondrial proteins. Cox17 being an important substrate of Mia40 is also an IDP that induces conformational changes in Mia40 upon binding. In this study, we focused on analysing the effects of the intrinsically disordered regions (IDR’s) in Mia40 and the presence of Cox17 in inducing conformational changes in Mia40. The conformational changes in the lipid environment were analysed using the molecular dynamics studies in the presence and absence of IDR’s and Cox17. Cox17 and Mia40 IDR’s influence in the water transport mechanism across the membrane were analysed using water dynamics. The results show that the Cox17 binding has induced the formation of an α-helical structure in the IDR residues of Mia40. Both the IDR residues and Cox17 enhance the water pore formation through the mitochondrial membrane.
Additional file 1: of Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples
Creators: name: Coppens, Jasmine
name: Heirstraeten, Liesbet
name: Ruzin, Alexey
name: Yu, Li
name: Timbermont, Leen
name: Lammens, Christine
name: Matheeussen, Veerle
name: McCarthy, Michael
name: Jorens, Philippe
name: Ieven, Margareta
name: Kumar-Singh, Samir
name: Goossens, Herman
name: Malhotra-Kumar, Surbhi
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Table S1. Overview of the results obtained on 79 ETAs using SQ-culture, the GeneXpert assay, Q-culture, enrichment-based culture, and in-house nuc gene-based qPCR. 0-4: negative (0), light (1), moderate (2) and heavy (3). (PDF 88 kb)
Xenorhipis brendeli LeConte 1866
Creators: name: Carlton, Christopher E.
name: MacRae, Ted C.
name: Tishechkin, Alexey K.
name: Bayless, Victoria L.
name: Johnson, Wood
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Buprestidae
Xenorhipis
Xenorhipis brendeli

description: 44. Xenorhipis brendeli LeConte, 1866
 Parish records (n = 3): East Baton Rouge and Franklin Parishes (LSAM).
 Potential larval hosts in Louisiana: Betula nigra, Carya glabra, Carya illinoinensis, Carya laciniosa, Carya ovata, Cercis canadensis, and Quercus alba. Adults reported also on Fagus sp., Gleditsia triacanthos, Quercus virginiana, and Quercus velutina.
Collection date range: 15 May–17 July.
 Comments: Collected using canopy Malaise traps, also as  C. fumipennis prey .
Tribe Melanophilini
description: Published as part of Carlton, Christopher E., MacRae, Ted C., Tishechkin, Alexey K., Bayless, Victoria L. & Johnson, Wood, 2018, Annotated Checklist of the Buprestidae (Coleoptera) from Louisiana, pp. 351-367 in The Coleopterists Bulletin 72 (2) on page 357, DOI: 10.1649/0010-065X-72.2.351, http://zenodo.org/record/5382706
New code for equilibriums and quasiequilibrium initial data of compact objects. IV. Rotating relativistic stars with mixed poloidal and toroidal magnetic fields
Creators: name: Uryu, Koji
name: Yoshida, Shijun
name: Gourgoulhon, Eric
name: Markakis, Charalampos
name: Fujisawa, Kotaro
name: Tsokaros, Antonios
name: Taniguchi, Keisuke
name: Eriguchi, Yoshiharu
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: A new code for computing fully general relativistic solutions of strongly magnetized rapidly rotating compact stars is developed as a part of the COCAL (Compact Object CALculator) code. The full set of Einstein's equations, Maxwell's equations and magnetohydrodynamic equations are consistently solved assuming perfect conductivity, stationarity, and axisymmetry, and strongly magnetized solutions associated with mixed poloidal and toroidal components of magnetic fields are successfully obtained in generic (non-circular) spacetimes. We introduce the formulation of the problem and the numerical method in detail, then present examples of extremely magnetized compact star solutions and their convergence tests. It is found that, in extremely magnetized stars, the stellar matter can be expelled from the region of strongest toroidal fields. Hence we conjecture that a toroidal electro-vacuum region may appear inside of the extremely magnetized compact stars, which may seem like the neutron star becoming the strongest toroidal solenoid coil in the universe.
description: 30 pages, 4 figures
Megaselia claudia Borgmeier 1967
Creators: name: DISNEY, R. H. L.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Phoridae
Megaselia
Megaselia claudia

description: Megaselia claudia Borgmeier, 1967
(figures 13C, 14)
 Megaselia claudia Borgmeier, 1967b: 180.
 This species was previously known from mainland Australia (NSW, QSLD) (Borgmeier, 1967b), but is more variable (in colour, size, costal index, costal ratios, relative size of bristles, etc.) than Borgmeier realized. I now report it not only from Tasmania but also Western Australia. However, in the latter region it belongs to a complex of sibling species, of which all but M. claudia have yet to be described. The distinctive male hypopygium and the single pair of enormous SPS vesicles in the third antennal segment have proved to be valuable recognition features; but the pair of large vesicles are characteristic of most of the species complex in Western Australia.
 Material
 Eighteen males, 14 females, Tasmania, Hobart, Battery Point, De Witt Street, garden, 23–31 December 1991 (R. H. L. Disney —25-4, 34); 28 males, 15 females, same locality, 1–11 January 1992 (RHLD —25-6, 7, 39); 6 males, 6 females, same locality, 10–12 June 1995 (RHLD —25-21); male, female, Mt Field National Park, Russell Falls, 26 December 1991 (RHLD —25-5); male, same locality, 11 January 1992 (RHLD —25-8); 65 males, 67 females, Hobart, Sandy Bay, Acushla Court, garden, 16–19, 23–26 September 1998 (RHLD —25-22, 25-4, 25-30); 3 males, Lake St Clair, near Cynthia Bay, 20 September 1998 (RHLD —25-26). 7 males, Fern Tree, Grays Road, 147°15∞E, 42°57∞S (grid ref. 203474), 540 m altitude, 7–17 August 2000 (RHLD —25-41-45). 2 males, Western Australia, 33°22∞S, 116°05∞E and 33°24∞S, 116°20∞E, 10–12 October 1996 (Cindy Brown, 25-10 and 13).
 Natural history
Two females had the gut full of a brownish sludge of detrital material, one of which included many fungal spores. Several females had a suspension of purplish particles (mostly 1–2 microns in diameter) in the gut. Gravid females had 10–22 nearly mature eggs, the larger specimens having the larger numbers.
description: Published as part of DISNEY, R. H. L., 2003, Tasmanian Phoridae (Diptera) and some additional Australasian species, pp. 505-639 in Journal of Natural History 37 (5) on page 538, DOI: 10.1080/00222930110096564, http://zenodo.org/record/5273495
Microsecond scale sampling of Egr-1 conformational landscape to decipher the impact of its disorder regions on structure–function relationship
Creators: name: Hemavathy Nagarajan
name: Vetrivel, Umashankar
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Early growth response-1 (Egr-1) is one of the key zinc finger transcription factors involved in controlling cell growth, proliferation, differentiation, angiogenesis and apoptosis. It also plays a pivotal role in conditions like cancer, neurological disorders and ocular disorders. The structural features of Egr-1 DNA-binding domain (DBD) are well documented, however, the functional role of its intrinsically disordered regions (IDRs) is yet to be explored. Hence, in this study, 3D structure of Egr-1 was modelled in conjunction with its IDR and was probed for conformational changes at microsecond scale in order to explore the structural plasticity and its functional impact. The results revealed the distortion of Zinc binding was due to the secondary structure transitions and flexibility of the DBD residues. Moreover, the increased distance of the flap residues that contributes to the proper orientation of Zinc interactions were also inferred, which shall aid in proper binding of DNA. This study also portrays the conformations that can be considered as optimal near-natives for further protein–protein interaction studies to delineate its interacting partners involved in various pathological conditions. This study demonstrates the impact of IDRs in Egr-1 on structure–function studies and also provides insights on optimal druggable cavities..
Synthesis of 5, 6-diaroylisoindoline-1, 3-dione and computational approaches for investigation on structural and mechanistic insights by DFT
Creators: name: Hoque, Mohammad Mazharol
name: Md. Sajib Hussen
name: Ajoy Kumer
name: Md. Wahab Khan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: This study represents a theoretical investigation of the coupling reaction between isoindoline-1, 3-dione (phthalimide) and aroyl chloride. Firstly, density functional theory (DFT) was employed to explore the structural insights of the coupled product 5, 6-diaroyl isoiondoline-1, 3-dione. The dispersion corrected functional ωB97X-D was applied to determine the transition states of the coupling reaction in the gas phase and in the solution phase by the SMD solvation model. In two-step mechanism, the calculated results indicate that the energy barrier of the C–C bond formation between benzoyl cation and phthalimide is the rate determining step of the reaction, and the activation energy was found 53.3 kcal/mol in1,4-dioxane. Moreover, thermodynamic calculation shows that the aroylation reactions are either spontaneous or nonspontaneous depending on the aroyl halide used although all these reactions are exothermic. However, B3LYP/6-311+G (d, p) functional was applied to compute equilibrium geometry, HOMO–LUMO energy gap (3.9–4.1 eV), dipole moments, polarizability and first order hyper polarizability to understand the structural features of the products. Moreover, experimental and computed FT-IR analysis of the phthalimide derivatives showed well correlation. Finally, for the synthesis of 5, 6-diaroyl isoiondoline-1, 3-dione from phthalimide and aroyl halide is herein described.
Melanophila atropurpurea
Creators: name: Carlton, Christopher E.
name: MacRae, Ted C.
name: Tishechkin, Alexey K.
name: Bayless, Victoria L.
name: Johnson, Wood
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Buprestidae
Melanophila
Melanophila atropurpurea

description: 45. Melanophila atropurpurea (Say, 1823)
 Parish records (n = 1): St. Tammany Parish (LSAM).
 Potential larval host in Louisiana: Unknown, possibly Pinus spp.
Collection date: 13 August.
 Comments: New State Record: St. Tammany Parish, 4.2 mi N Abita Springs, 30.5162°N, 89.9547°W, collected at mercury vapor light, 13 Aug. 2007, V. Brou (n = 1).
description: Published as part of Carlton, Christopher E., MacRae, Ted C., Tishechkin, Alexey K., Bayless, Victoria L. & Johnson, Wood, 2018, Annotated Checklist of the Buprestidae (Coleoptera) from Louisiana, pp. 351-367 in The Coleopterists Bulletin 72 (2) on page 357, DOI: 10.1649/0010-065X-72.2.351, http://zenodo.org/record/5382706
An Observational Study for Grain Dynamics in the AS 209 Disk with Submillimeter Polarization
Creators: name: Mori, Tomohiro
name: Kataoka, Akimasa
name: Ohashi, Satoshi
name: Momose, Munetake
name: Muto, Takayuki
name: Nagai, Hiroshi
name: Tsukagoshi, Takashi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present 870 $μ$m ALMA polarization observation toward the Class I\hspace{-.1em}I protoplanetary disk around AS 209, which has concentric, multiple gaps and rings. We successfully detect the polarized emission and find that the polarization orientations and fractions have distinct characteristics between the inner and outer regions. In the inner region, the polarization orientations are parallel to the minor axis of the disk, which is consistent with the self-scattering model. The mean polarization fraction in the region is $\sim$0.2\%, which is lower than the expected value when the grains have the maximum polarization efficiency, which corresponds to $λ$/2$π$ $\sim$ 140 $μ$m in grain radius. In the outer region, we detect $\sim$1.0\% polarization and find that the polarization orientations are almost in the azimuthal directions. Moreover, the polarization orientations have systematic angular deviations from the azimuthal directions with $Δ$$θ$ $\sim$ 4\fdg5 $\pm$ 1\fdg6. The pattern is consistent with a model that radially drifting dust grains are aligned by the gas flow against the dust grains. We consider possible scenarios of the grain dynamics at the AS 209 ring which can reproduce the polarization pattern. However, the directions of the observed angular deviations are opposite to what is predicted under the fact that the disk rotates clockwise. This poses a question in our understandings of the alignment processes and/or grain dynamics in protoplanetary disks.
description: 14 pages, 7 figures
Robust Semantic Segmentation in Adverse Weather Conditions by means of Sensor Data Fusion
Creators: name: Pfeuffer, Andreas
name: Dietmayer, Klaus
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: A robust and reliable semantic segmentation in adverse weather conditions is very important for autonomous cars, but most state-of-the-art approaches only achieve high accuracy rates in optimal weather conditions. The reason is that they are only optimized for good weather conditions and given noise models. However, most of them fail, if data with unknown disturbances occur, and their performance decrease enormously. One possibility to still obtain reliable results is to observe the environment with different sensor types, such as camera and lidar, and to fuse the sensor data by means of neural networks, since different sensors behave differently in diverse weather conditions. Hence, the sensors can complement each other by means of an appropriate sensor data fusion. Nevertheless, the fusion-based approaches are still susceptible to disturbances and fail to classify disturbed image areas correctly. This problem can be solved by means of a special training method, the so called Robust Learning Method (RLM), a method by which the neural network learns to handle unknown noise. In this work, two different sensor fusion architectures for semantic segmentation are compared and evaluated on several datasets. Furthermore, it is shown that the RLM increases the robustness in adverse weather conditions enormously, and achieve good results although no disturbance model has been learned by the neural network.
BeppoSAX Spectral Survey of BL Lacs - new spectra and results
Creators: name: Beckmann, V.
name: Wolter, A.
name: Celotti, A.
name: Costamante, L.
name: Ghisellini, G.
name: Maccacaro, T.
name: Tagliaferri, G.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present BeppoSAX LECS, MECS, and PDS spectra of eleven X-ray selected BL Lacertae objects. Combining these sources with the ones presented elsewhere we have a sample of 21 BL Lacs from the Einstein Medium Sensitivity and Einstein Slew Survey. The sample shows strong correlations of several physical parameters with the peak frequency of the synchrotron branch of the spectral energy distribution. In particular the peak frequency is correlated to the X-ray spectral shape: objects with the peak near to the X-ray band show harder and straighter X-ray spectra than those of the low energy peaked sources. This work shows that the recently proposed unification scenario for different types of blazars can hold also within the class of high frequency peaked BL Lac objects.
description: 14 pages, 9 figures, accepted by A&A
Phaenops aeneola
Creators: name: Carlton, Christopher E.
name: MacRae, Ted C.
name: Tishechkin, Alexey K.
name: Bayless, Victoria L.
name: Johnson, Wood
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Buprestidae
Phaenops
Phaenops aeneola

description: 47. Phaenops aeneola (Melsheimer, 1845)
 Parish records (n = 6): Caddo, Calcasieu, Grant, St. Helena, Tangipahoa, and Vernon Parishes.
 Potential larval hosts in Louisiana: Unknown, probably Pinus spp. Adults reported on Pinus echinata.
Collection date range: 13 May–5 June.
 Comments: All specimens collected by beating Pinus spp.
description: Published as part of Carlton, Christopher E., MacRae, Ted C., Tishechkin, Alexey K., Bayless, Victoria L. & Johnson, Wood, 2018, Annotated Checklist of the Buprestidae (Coleoptera) from Louisiana, pp. 351-367 in The Coleopterists Bulletin 72 (2) on page 357, DOI: 10.1649/0010-065X-72.2.351, http://zenodo.org/record/5382706
The relationship between job satisfaction and job performance case study at baidoa electric company (BECO).
Creators: name: Omar, Ahmed Ibrahim
Publisher: name: Zenodo
Year: 2025
Subjects: job satisfaction
job performance

description: ABSTRACT

The study will be descriptive; cross sectional and quantitative in design.it will be cross sectional in nature because I intended to collect data at a given point in time from cross section of respondents in Mogadishu-Somalia. The study will adopt a descriptive research design because it intends to describe the constraints of team work in University of Somalia. Analysis of data in this study was done concurrently with data collection. After data collection the questionnaires of respondents were sorted out accordingly; responses were verified, coded, categorized and entered into the computer using statistical package for Social Sciences (SPSS) version 20.0 software.

 

Most of respondents According to question one the respondents said about based on gender for the highest rate of the gender 68.75% of them where male was the rest of them were female 31.25% most of the respondents (73.75%) were 20-40, (41-60) were 23.75%), (2.5%) were Above 60. most

of the respondents (62.50%) were Single, (28.75%) were Married 23.75%), (2.5%) were Above

60. most of the respondents (85.0%) were Tertiary, (15%) were Secondary. most of the respondents (43.75%) were un employed, (31.25%) were formal employed, (25.0%) were Self-employed.
Molecular modelling study on pyrrolo[2,3-b]pyridine derivatives as c-Met kinase inhibitors: a combined approach using molecular docking, 3D-QSAR modelling and molecular dynamics simulation
Creators: name: Pouria Shirvani
name: Fassihi, Afshin
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Mesenchymal-epithelial transition factor (c-Met), also known as hepatocyte growth factor receptor (HGFR) is a unique member of receptor tyrosine kinase (RTKs) family. Dysregulation of c-Met/HGF signalling pathway is validated in a variety of human proliferative diseases. Therefore, targeting c-Met has become a promising strategy in anti-proliferative drug discovery. In this work, an integrated computational approaches were performed on 67 c-Met inhibitors to explore the structural requirements for their activity. Molecular docking was performed to elucidate their binding mode in c-Met active site. Subsequently, 3D-QSAR models were constructed using comparative molecular filed analysis (CoMFA q2 = 0.692, r2 = 0.912 and r2pred = 0.897) and comparative molecular similarity indices analysis (CoMSIA q2 = 0.751, r2 = 0.946 and r2pred = 0.944) techniques. The CoMSIA map analysis showed that hydrophobic contours play key role for inhibitory activity. According to docking and 3D-QSAR results, A total of 31 novel c-Met inhibitors with predicted improved activity were designed. A 100 ns molecular dynamics simulation and binding free energy calculations using the MM-PBSA method revealed the stability of the designed compound D12 inside the c-Met active site. In summary , the results of our study could provide significant insight for future design and development of novel c-Met kinase inhibitors.
Additional file 2: of Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression
Creators: name: Floris, Andrea
name: Luo, Jia
name: Frank, Jacqueline
name: Zhou, Jennifer
name: OrrĂš, Sandro
name: Biancolella, Michela
name: Pucci, Sabina
name: Orlandi, Augusto
name: Campagna, Paolo
name: Balzano, Antonella
name: Ramani, Komal
name: Tomasi, Maria
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Table S2. STARD10 expression in human breast cancer databases. Biological replicates (Rep.) are parallel measurements of biologically distinct samples that capture random biological variation. (DOCX 358 kb)
Chrysobothris adelpha Harold 1869
Creators: name: Carlton, Christopher E.
name: MacRae, Ted C.
name: Tishechkin, Alexey K.
name: Bayless, Victoria L.
name: Johnson, Wood
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Buprestidae
Chrysobothris
Chrysobothris adelpha

description: 50. Chrysobothris adelpha Harold, 1869
 Parish records (n = 17): Concordia Parish (LSAM).
 Potential larval hosts in Louisiana: Amelanchier arborea, Carya glabra, Carya illinoinensis, Carya laciniosa, Carya ovata, Carya tomentosa, Prosopis glandulosa. Adults reported also on Fraxinus pennsylvanica Marsh. and Quercus sp.
 Collection date range: 30 April–15 July, mostly in June (n = 8).
Comments: All specimens collected by canopy Malaise traps.
description: Published as part of Carlton, Christopher E., MacRae, Ted C., Tishechkin, Alexey K., Bayless, Victoria L. & Johnson, Wood, 2018, Annotated Checklist of the Buprestidae (Coleoptera) from Louisiana, pp. 351-367 in The Coleopterists Bulletin 72 (2) on page 358, DOI: 10.1649/0010-065X-72.2.351, http://zenodo.org/record/5382706
The Non-Thermal Sunyaev-Zel'dovich Effect in Clusters of Galaxies
Creators: name: Colafrancesco, S.
name: Marchegiani, P.
name: Palladino, E.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: In this paper we provide a general derivation of the non-thermal (as well as of the thermal) SZ effect in galaxy clusters which is exact in the Thomson limit to any approximation order in the optical depth. Such a general derivation is obtained using the full relativistic formalism and overcoming the limitations of the Kompaneets and of the single scattering approximations. To have a consistent description of the SZ effect in clusters containing non-thermal phenomena, we also evaluate in a consistent way - for the first time - the total SZ effect produced by a combination of thermal and non-thermal electron populations residing in the same environment, like is the case in radio-halo clusters. We discuss both the spectral and the spatial features of the total SZ effect and we provide specific predictions for a well studied radio-halo cluster like A2163. We also discuss the overall SZ effect produced by a combination of different thermal populations residing in the cluster atmosphere. In this context, we discuss how the combined observations of the thermal and non-thermal SZ effect provide constraints on the spectrum of the relativistic electron population and, in turn, on the presence and on the origin of non-thermal phenomena (radio-halo, hard X-ray, EUV excesses) occurring in galaxy clusters.
description: 40 pages, 29 figures, 13 Tables. To appear in A&A. A&A in press
Variable Chaplygin gas cosmologies in f(R, T) gravity with particle creation
Creators: name: Hulke, N.
name: Singh, G. P.
name: Bishi, Binaya K.
name: Singh, A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A flat FLRW cosmological model with perfect fluid comprising of variable Chaplygin gas has been studied in context of f(R; T) gravity with particle creation. The considered scale factors describe the accelerated expansion of universe due to the effective negative pressure produced during evolution of universe. The role of particle creation pressure on the cosmological parameters have been discussed in detail. By considering well accepted values of free parameters, the late time expansion of the universe with energy conditions have also been studied. The state-finder diagnostic for the considered cases have been studied and the evolution of source function with time have suggested almost constant particle production at late times.
Correlated many-body treatment of Breit interaction with application to cesium atomic properties and parity violation
Creators: name: Derevianko, Andrei
Publisher: name: arXiv
Year: 2001
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Corrections from Breit interaction to basic properties of atomic 133Cs are determined in the framework of third-order relativistic many-body perturbation theory. The corrections to energies, hyperfine-structure constants, off-diagonal hyperfine 6S-7S amplitude, and electric-dipole matrix elements are tabulated. It is demonstrated that the Breit corrections to correlations are comparable to the Breit corrections at the Dirac-Hartree-Fock level. Modification of the parity-nonconserving (PNC) 6S-7S amplitude due to Breit interaction is also evaluated; the resulting weak charge of $^{133}$Cs shows no significant deviation from the prediction of the standard model of elementary particles. The neutron skin correction to the PNC amplitude is also estimated to be -0.2% with an error bound of 30% based on the analysis of recent experiments with antiprotonic atoms. The present work supplements publication [A. Derevianko, Phys. Rev. Lett. 85, 1618 (2000)] with a discussion of the formalism and provides additional numerical results and updated discussion of parity violation.
description: 16 pages; 5 figs; submitted to Phys. Rev. A
Chrysobothris caddo Wellso and Manley
Creators: name: Carlton, Christopher E.
name: MacRae, Ted C.
name: Tishechkin, Alexey K.
name: Bayless, Victoria L.
name: Johnson, Wood
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Buprestidae
Chrysobothris
Chrysobothris caddo

description: 51. Chrysobothris caddo Wellso and Manley,
 2007
 Parish records (n = 54): East Baton Rouge and Winn Parishes (LSAM).
 Potential larval hosts in Louisiana: Celtis laevigata Willd. and Cercis canadensis.
 Collection date range: 27 April–9 July, mostly in May (n = 47).
 Comments: Collected only as  C. fumipennis prey .
description: Published as part of Carlton, Christopher E., MacRae, Ted C., Tishechkin, Alexey K., Bayless, Victoria L. & Johnson, Wood, 2018, Annotated Checklist of the Buprestidae (Coleoptera) from Louisiana, pp. 351-367 in The Coleopterists Bulletin 72 (2) on page 358, DOI: 10.1649/0010-065X-72.2.351, http://zenodo.org/record/5382706
Low Energy Proton-Deuteron Scattering in Configuration Space
Creators: name: Chen, C. R.
name: Friar, J. L.
name: Payne, G. L.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A new method for solving the configuration-space Faddeev equations for elastic p-d scattering below the deuteron-breakup threshold is described. Numerical solutions that demonstrate the convergence and accuracy of the method are given. The number of channels and the value of the matching radius required to obtain an accurate solution are also investigated. These calculations demonstrate that this method can efficiently solve the large matrix equations required for the three-body scattering problem.
description: 11 pages, latex - FBSart.cls required
Równość albo sprawiedliwość – oto jest pytanie
Creators: name: Kubalica, Tomasz
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 480504
subject: Legal institutions (incl. courts and justice systems)

description: Zdecydowanie nie chcemy być traktowani niesprawiedliwie. Takie podejście rodzi w nas poczucie upokorzenia i skłania do buntu. Co to jednak znaczy „sprawiedliwie”? Czy sprawiedliwość musi oznaczać absolutną równość pod każdym względem? A może pewne nierówności mogą być sprawiedliwe?