cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death
Creators: name: Salah, F. S.
name: Ebbinghaus, M.
name: Muley, V. Y.
name: Zhou, Z.
name: Al-Saadi, K. R. D.
name: Pacyna-Gengelbach, M.
name: O'Sullivan, G. A.
name: Betz, H.
name: König, R.
name: Wang, Z-Q
name: Bräuer, R.
name: Petersen, I.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: GABARAP belongs to an evolutionary highly conserved gene family that has a fundamental role in autophagy. There is ample evidence for a crosstalk between autophagy and apoptosis as well as the immune response. However, the molecular details for these interactions are not fully characterized. Here, we report that the ablation of murine GABARAP, a member of the Atg8/LC3 family that is central to autophagosome formation, suppresses the incidence of tumor formation mediated by the carcinogen DMBA and results in an enhancement of the immune response through increased secretion of IL-1β, IL-6, IL-2 and IFN-γ from stimulated macrophages and lymphocytes. In contrast, TGF-β1 was significantly reduced in the serum of these knockout mice. Further, DMBA treatment of these GABARAP knockout mice reduced the cellularity of the spleen and the growth of mammary glands through the induction of apoptosis. Gene expression profiling of mammary glands revealed significantly elevated levels of Xaf1, an apoptotic inducer and tumor-suppressor gene, in knockout mice. Furthermore, DMBA treatment triggered the upregulation of pro-apoptotic (Bid, Apaf1, Bax), cell death (Tnfrsf10b, Ripk1) and cell cycle inhibitor (Cdkn1a, Cdkn2c) genes in the mammary glands. Finally, tumor growth of B16 melanoma cells after subcutaneous inoculation was inhibited in GABARAP-deficient mice. Together, these data provide strong evidence for the involvement of GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response.
title: Trustworthy chatbots assisting large-scale collaboration
Creators: name: Amiot, Clélie 
Publisher: name: European Society for Socially Embedded Technologies (EUSSET)
Year: 2020

description: Cognitive assistants are a promising solution to the increasing complexity of large-scale collaboration. By providing support in data processing and decision making, they could lighten the cognitive load put on human collaborators. More precisely, conversational agents are especially suited to large-scale collaboration as they are user-friendly and could be integrated into existing collaboration tools. However, to be successfully integrated into the collaboration process, the assistant needs to be trusted. My doctoral research aims to identify which factors determine trust in a chatbot’s advice during collaboration.
title: Risk prediction and decision making in policing – Humans, Algorithms and Data. (A study of processes at Bedfordshire, Hertfordshire and Cambridgeshire police)
Creators: name: Kazeem, Ganiat
Publisher: name: European Society for Socially Embedded Technologies (EUSSET)
Year: 2020

description: My inductive interpretivist study focusses on understanding of the police process of information collection/acquisition, management and exploitation during risk assessments and decision making in the counties of Bedfordshire, Cambridgeshire and Hertfordshire located outside the metropolitan area. It is examining the role of humans in the production (through interactions with staff in police control rooms), generation (during day to day policing) and creation (through intelligence collected via community policing and detectives investigating focused criminal issues) of information through ethnography. It is focussed on gathering narratives and perspectives to enable an understanding of the information cycle in policing and nature (culture, context, practices, processes) of information collection, management, use and exploitation and determining how these shape the use and exploitation of data generated. It also considers the critical issues related to use of information for risk assessment and decision making in policing using advanced metrics or statistics, algorithms and other advanced technologies.
title: Department of Transportation News Releases for September 1968
Creators: name: United States Department of Transportation
Publisher: name: United States Department of Transportation
publisherIdentifier: https://ror.org/02xfw2e90
publisherIdentifierScheme: ROR
Year: 1968
Subjects: classificationCode: https://trt.trb.org/term/88891
subject: Transportation policy
classificationCode: https://trt.trb.org/term/96618
subject: History
classificationCode: https://trt.trb.org/term/88537
subject: Management
classificationCode: https://trt.trb.org/term/91975
subject: Organizations
classificationCode: https://trt.trb.org/term/97447
subject: News

description: Department of Transportation News Releases for September 1968.
title: Department of Transportation News Releases for August 1970
Creators: name: United States Department of Transportation
Publisher: name: United States Department of Transportation
publisherIdentifier: https://ror.org/02xfw2e90
publisherIdentifierScheme: ROR
Year: 1970
Subjects: classificationCode: https://trt.trb.org/term/88891
subject: Transportation policy
classificationCode: https://trt.trb.org/term/96618
subject: History
classificationCode: https://trt.trb.org/term/88537
subject: Management
classificationCode: https://trt.trb.org/term/91975
subject: Organizations
classificationCode: https://trt.trb.org/term/97447
subject: News

description: Department of Transportation News Releases for August 1970.
IEA Wind Task 52 LAC Summer Games 2024
Creators: name: Schlipf, David
name: Guo, Feng
name: Liang, Zhi
name: Pitter, Mark
name: Lopez-Queija, Javier
name: Rinker, Jenni
name: Venkatachalapathy, Aravind
name: Weich, Simon
Publisher: name: Zenodo
Year: 2024

description: Description of our joined exercise and competition on Lidar-Assisted Control within the IEA Wind Task 52. 

 

Wind characteristics are inherently dynamic, subject to sudden changes in speed, direction, and turbulence. Consequently, wind turbines are highly dynamic systems, excited by such stochastic influences and must be designed to handle these variations and disturbances. Traditional controllers react only after wind changes have impacted the wind turbine, resulting in an offset operation until the controller handles the disturbance. Contrary, lidar-assisted control (LAC) concepts use preview information of the wind to anticipate changes, hence reacting before the disturbance approaches the rotor and therefore improving the operation of the turbine.

The mission of our IEA Wind Task 52 working group is to push forward the lidar-assisted control technology and simplify its application by recommended practices, open-source tools and joined exercises. In line with our mission, we are very glad to launch our LAC Summer Games 2024 to encourage students and professionals in the art of designing and deploying lidar data processing algorithms and lidar-assisted controllers.

By participating in the games, you can increase your knowledge in LAC and enjoy the design process by competing with others. Moreover, we aim to trigger your creativity in three different disciplines and with it motivate the development of new concepts. During the competition, it is intended that the participants learn the existing open-source tools and their application will result eventually in the further development of the tools. Additionally, during the games you will be able to exchange knowledge with different parties of the wind energy community. We are looking forward to enhancing your passion for enhancing the vision of modern wind turbines and getting the best LAC out of you!
title: Understanding and predicting team performance
title: a collaboration perspective
titleType: Subtitle
Creators: name: Lee, Sulyun
Publisher: name: University of Iowa
Year: 2025
Subjects: Social network
Team collaboration
Team Performance
public abstract

description: Collaboration is an important way to pool resources and expertise from a team and achieve goals that are difficult for individuals.As human beings tackle more complex problems, collaboration is becoming more prevalent and important.
description: Thus, better understanding and predicting team performance from collaboration patterns can aid team management and decision-making on personnel selections.
description: Specifically, team members use their skills, knowledge, expertise, and tactics learned from their previous collaboration experiences for subsequent collaborations.
description: Yet, there are limited studies that focus on individuals' previous collaboration experiences to connect to future team performance.
description: This dissertation conducts data-driven analyses to study team performance in two different contexts.
description: First, using large-scale scholarly data, I study the association between the expertise of scholars obtained from their research experiences and research team performance.In particular, I discover the different effects of scholars' experience in emerging and established fields.
description: In order to explain how much collaboration factors contribute to team performance, I adopt explanatory models.
description: Second, I study sports teams that have hierarchical structures among collaborators to discover the effects of individuals' hierarchical collaborations on team performance.Since most real-world teams consist of individuals holding different authorities, understanding hierarchical collaborations is crucial in better predicting team performance rather than flat team structures.
description: I adopt a predictive model, and propose a deep learning framework that 1) represents team members into lower-dimensional vectors based on their hierarchical collaboration experience, 2) learns representations of teams by aggregating team members' vectors in consideration of their hierarchical levels, and 3) predicts sports team performance using the team representations.
description: The implications of this dissertation are not limited to team management in research and sports.The proposed modeling framework and graph representation models can be generalized to research on team performance in other domains where collaborations have a critical impact on future team performance.
Prüfung und Validierung der Einsatzmöglichkeiten neuartiger Passivsammler für die Überwachung prioritärer Schadstoffe unter der WRRL, der MSRL und im Rahmen von HELCOM und OSPAR
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Passivsammler
subject: Binnengewässer
subject: EG-Wasserrahmenrichtlinie
subject: EG-Meeresstrategie-Rahmenrichtlinie
subject: Validierung
subject: Nordsee
subject: Ostsee
subject: Wasserschadstoff
subject: WRRL
subject: MSRL
subject: HELCOM
subject: OSPAR
subject: Chemikalien
subject: Wasser
subject: Chemicals
subject: Water

description: Passivsammler zur Bestimmung von Schadstoffen in Gewässern sind seit etwa 20 Jahren Gegenstand intensiver Forschung und werden heute z. B. im Rahmen der Überwachung nach WRRL als ergänzende Probenahmetechnik diskutiert [3]. Es bestehen jedoch noch erhebliche Unsicherheiten hinsichtlich der Kalibrierung der Sammler und der Validität der Ergebnisse. Deshalb besteht weiterer Forschungsbedarf, insbesondere bezüglich der Einsatzmöglichkeiten und -grenzen von Passivsammlerin bei der Gewässerüberwachung. Ziel dieses Projektes war es, verschiedene Passivsammler für die Bestimmung von prioritären Schadstoffen in Binnen- und marinen Gewässern zu testen. Dazu wurden
Beprobungsstellen in Elbe und Mulde sowie Nord- und Ostsee etabliert. Darüber hinaus sollte die Vorbereitung, Ausbringung und Analyse der Sampler für den Routineeinsatz optimiert und das Verfahren einer Validierung unterzogen werden.
Quelle: https://www.umweltbundesamt.de/
description: Passivsammler zur Bestimmung von Schadstoffen in Gewässern sind seit etwa 20 Jahren Gegenstand intensiver Forschung und werden heute z. B. im Rahmen der Überwachung nach WRRL als ergänzende Probenahmetechnik diskutiert [3]. Es bestehen jedoch noch erhebliche Unsicherheiten hinsichtlich der Kalibrierung der Sammler und der Validität der Ergebnisse. Deshalb besteht weiterer Forschungsbedarf, insbesondere bezüglich der Einsatzmöglichkeiten und -grenzen von Passivsammlerin bei der Gewässerüberwachung. Ziel dieses Projektes war es, verschiedene Passivsammler für die Bestimmung von prioritären Schadstoffen in Binnen- und marinen Gewässern zu testen. Dazu wurdenBeprobungsstellen in Elbe und Mulde sowie Nord- und Ostsee etabliert. Darüber hinaus sollte die Vorbereitung, Ausbringung und Analyse der Sampler für den Routineeinsatz optimiert und das Verfahren einer Validierung unterzogen werden.
title: Department of Transportation News Releases for November 1969
Creators: name: United States Department of Transportation
Publisher: name: United States Department of Transportation
publisherIdentifier: https://ror.org/02xfw2e90
publisherIdentifierScheme: ROR
Year: 1969
Subjects: classificationCode: https://trt.trb.org/term/88891
subject: Transportation policy
classificationCode: https://trt.trb.org/term/96618
subject: History
classificationCode: https://trt.trb.org/term/88537
subject: Management
classificationCode: https://trt.trb.org/term/91975
subject: Organizations
classificationCode: https://trt.trb.org/term/97447
subject: News

description: Department of Transportation News Releases for November 1969.
title: Understanding and Supporting Daily Planning in Knowledge Work
Creators: name: Ahmetoglu, Yoana
Publisher: name: European Society for Socially Embedded Technologies (EUSSET)
Year: 2020

description: Daily planning habits and skills have an impact on workers’ productivity and job performance. While daily planning is essential for modern work, daily plans can often be challenging to execute. My PhD research has investigated the errors and challenges knowledge workers experience when planning their work day. A diary study was conducted with 20 academics as participants to learn how tasks are planned at the start of the day and which tasks are actually completed during the day. Results showed that while participants were good at estimating the duration of time-constrained tasks, they were not very good at estimating the duration of less time-constrained tasks (e.g. the time needed for email and coding tasks was underestimated, whereas the time needed for writing research and planning activities was overestimated). My future work aims to develop and test planning and scheduling (AI) tools to better support knowledge workers daily planning habits and overcome these time estimation biases in their work.
title: Department of Transportation News Releases for February 1972
Creators: name: United States Department of Transportation
Publisher: name: United States Department of Transportation
publisherIdentifier: https://ror.org/02xfw2e90
publisherIdentifierScheme: ROR
Year: 1972
Subjects: classificationCode: https://trt.trb.org/term/88891
subject: Transportation policy
classificationCode: https://trt.trb.org/term/96618
subject: History
classificationCode: https://trt.trb.org/term/88537
subject: Management
classificationCode: https://trt.trb.org/term/91975
subject: Organizations
classificationCode: https://trt.trb.org/term/97447
subject: News

description: Department of Transportation News Releases for February 1972.
The High Time Resolution Universe Pulsar Survey -VIII. The Galactic millisecond pulsar population
Creators: name: Levin, L.
name: Bailes, Matthew
name: Barsdell, B. R.
name: Bates, S. D.
name: Bhat, N. D. R.
name: Burgay, M.
name: Burke-Spolaor, S.
name: Champion, D. J.
name: Coster, P.
name: D'Amico, N.
name: Jameson, A.
name: Johnston, S.
name: Keith, M. J.
name: Kramer, M.
name: Milia, S.
name: Ng, C.
name: Possenti, A.
name: Stappers, B.
name: Thornton, D.
name: van Straten, Willem
Publisher: name: Swinburne
Year: 2024

description: We have used millisecond pulsars (MSPs) from the southern High Time Resolution Universe (HTRU) intermediate latitude survey area to simulate the distribution and total population of MSPs in the Galaxy. Our model makes use of the scalefactor method, which estimates the ratio of the total number of MSPs in the Galaxy to the known sample. Using our best-fitting value for the z-height, z = 500 pc, we find an underlying population of MSPs of 8.3(+/-4.2) x 104 sources down to a limiting luminosity of Lmin =0.1mJy kpc2 and a luminosity distributionwith a steep slope of d log N/d log L = -1.45 +/- 0.14. However, at the low end of the luminosity distribution, the uncertainties introduced by small number statistics are large. By omitting very low luminosity pulsars, we find a Galactic population above Lmin = 0.2mJy kpc2 of only 3.0(+/-0.7) x 104 MSPs. We have also simulated pulsars with periods shorter than any known MSP, and estimate the maximum number of sub-MSPs in the Galaxy to be 7.8(+/-5.0) x 104 pulsars at L = 0.1mJy kpc2. In addition, we estimate that the high and low latitude parts of the southern HTRU survey will detect 68 and 42 MSPs, respectively, including 78 new discoveries. Pulsar luminosity, and hence flux density, is an important input parameter in the model. Some of the published flux densities for the pulsars in our sample do not agree with the observed flux densities from our data set, and we have instead calculated average luminosities from archival data from the Parkes Telescope. We found many luminosities to be very different than their catalogue values, leading to very different population estimates. Large variations in flux density highlight the importance of including scintillation effects in MSP population studies.
Urban Mining
Creators: name: Bolland, Til
name: Keßler, Hermann
name: Kosmol, Jan
name: Lehmann, Christian
name: Müller, Felix
Publisher: name: My University
Year: 2017
Subjects: subject: Urban Mining
subject: Abfall | Ressourcen

description: In der Wissenschaft seit Jahren bekannt, hat sich das Urban Mining-Konzept zu einem Modewort entwickelt. Es beschreibt die quasi bergmännische Rohstoffgewinnung im urbanen Raum Ń in der Stadt wie auch in der Kommune. Das Umweltbundesamt will mit dieser Broschüre ein gemeinsames Verständnis zum Urban Mining vermitteln und dazu ermutigen, mit diesem Strategieansatz konsequent voranzuschreiten. Quelle: www.umweltbundesamt.de
description: In der Wissenschaft seit Jahren bekannt, hat sich das Urban Mining-Konzept zu einem Modewort entwickelt. Es beschreibt die quasi bergmännische Rohstoffgewinnung im urbanen Raum – in der Stadt wie auch in der Kommune. Das Umweltbundesamt will mit dieser Broschüre ein gemeinsames Verständnis zum Urban Mining vermitteln und dazu ermutigen, mit diesem Strategieansatz konsequent voranzuschreiten.
Effects of dilution and symmetry on concentrated ionic solutions
Creators: name: Horvath, Andrew William Gerard
Publisher: name: University of Iowa
Year: 2023
Subjects: Ionic Liquids
Spectroscopic Ellipsometry
Vibrational Spectroscopy
public abstract
Electrochemistry
Interfaces
Thin Films

description: Even though the interfaces control systems around them, the physicochemical behavior of molecules at interfaces is an often poorly understood subject. There have been several studies demonstrating the ability of molecules to form complex ordered structures at the interface that can have significant effects on the on the behavior and dynamics of molecules at the interface. Properties affected include but are not limited to: localized increase in viscosity, decreased mass transport through the interface, and solvent reorganization. Such properties have major implications for applications of materials in everyday life, showing need for further studies. Most of this dissertation is focused on the study of a class of molecules known as ionic liquids (ILs). ILs are akin to common salts such as sodium chloride, which is made up of relatively small and symmetric anions and cations. However, unlike common salts, ILs are made of bulky asymmetric ions which do not readily crystalize. Many ILs remain liquid at room temperature. This gives ILs several interesting properties including negligible vapor pressure, relatively high conductivity, and high thermal stability. As such ILs have found use in a wide variety of applications in the fields of tribology, energy storage, and catalysis.
description: Understanding the behaviors of ILs at interfaces is paramount to designing new classes of ILs for innovative applications. The work presented herein uses a combination of vibrational spectroscopy and electrochemistry to probe the structures formed by ILs at interfaces. The aim of this research is to determine the effects of changing IL composition and mixing of ILs with molecular solvents on the structure and dynamics of ILs at interfaces. A secondary aim is to explore applications of mixtures of ILs in the fields of biomass processing and energy storage.
description: Another section of this dissertation takes the information gained from complex systems like ionic liquids and applies them to other energy storages systems. In these applications, there are equally concentrated solutions that aim to create redox flow batteries.
description: The outcomes of this research shed light on the interfacial and bulk behavior of ILs, under the influence shear, electric fields, and solvent dilution. This will provide valuable insights into new design principles for truly task specific ILs. Results from these studies can be applied to other systems such as redox flow batteries for fundamental studies in renewable energy storage systems.
By- og baneplanlægning i det østjyske bybånd
Creators: name: Jørgensen, Jan
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2012

description: Grundlaget for bedre togbetjening i det østjyske bybånd kan forbedres væsentligt gennem stationsnær lokalisering og byfortætning I modsætning til Hovedstadsområdet, hvor Fingerplanen regulerer byudviklingen, er der i det østjyske bybånd ikke nogen overordnet plan for byudviklingen. Kommuneplanerne i det østjyske bybånd repræsenterer samlet set en bilorienteret byudvikling med et begrænset vækstpotentiale for togtrafikken. En struktureret fysisk planlægning – i form af en mere togorienteret byudvikling – kan medføre omtrent dobbelt så stort vækstpotentiale for togtrafikken som den planlagte byudvikling. En togorienteret byudvikling kan dermed skabe et væsentligt bedre grundlag for fremtidige forbedringer i togtrafikken. Det er primært regionalt orienterede rejsemål, herunder kontorarbejdspladser, uddannelsessteder og større butikscentre, der bør lokaliseres stationsnært. Etageboliger kan også med fordel placeres tæt på stationerne for at skabe levende bymiljøer med både boliger og erhverv. En togorienteret byudvikling forudsætter plads til mere byudvikling tæt på stationerne. Der vurderes generelt at være et betydeligt potentiale for byfortætning omkring stationerne i det østjyske bybånd. Nogle steder er der umiddelbart gode muligheder for at bygge tættere. Andre steder kræver det en mere gennemgribende byomdannelse.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2012): Proceedings from the Annual Transport Conference at Aalborg University
Plant mitochondrial L2 ribosomal protein genes and their expression.
Creators: name: Subramanian, Selvi.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Biology, Molecular.

description: The endosymbiotic hypothesis for the origin of mitochondria invokes the transfer of many genes from the respiring bacterium to the nucleus of the host cell early in the symbiotic association. Recent evidence suggests that such transfer is an ongoing evolutionary process in the plant lineage. This project focuses on the location and expression of genes coding for the mitochondrial (mt) large ribosomal subunit protein L2 in different plants to gain knowledge about their function and evolution. L2 is known to be one of the most conservative ribosomal proteins present in prokaryotes and eukaryotes. The rice mt genome was found to have a single copy of a functional rpl2 gene with a group II intron whereas wheat has only a truncated rpl2 pseudogene corresponding to the extreme carboxyl terminus and no rpl2 homologous sequences were detected in the soybean mt genome. Nuclear-located transferred mt rpl2 copies have been identified in wheat and they are found to be transcribed. An RNA-mediated gene transfer is predicted since it lacks the mt intron at the expected splice site. In rice, the mt rpl2 gene is transcribed, spliced and edited. The mRNA levels of the rice mt rpl2 are very low compared to typical respiratory chain genes and have higher transcript accumulation in the germinating embryo stage than seedlings. The transcript profile is complex and different between stages indicating different processing pathways in germinating embryos and seedlings. Low steady state rpl2 mRNA levels compared to excised introns indicate a rapid turnover of mRNA and a stable excised form of intron. However the excised introns appear to be present as non-lariat forms by RT-PCR experiments. This observation suggests an initial hydrolysis step in the splicing reaction. Phylogenetic analyses on derived L2 and S12 protein sequences of mitochondria and other compartments indicate a rapid evolution of mt L2 proteins in comparison to mt S12. The transfer of mt genes to the nucleus points to an accelerated rate of evolution of L2 proteins. The codon usage pattern of the transferred wheat nuclear-located mt rpl2 sequences is in agreement with an adaptation to the pattern of other wheat nuclear genes. This study illustrates the recent evolutionary transfer of functional mt genes to the nucleus. It also indicates that the transferred genes may be modified to a certain extent during or after transfer to the new environment. The presence of a mitochondrial as well as a transferred nuclear copy may reflect the transition stage in a gene transfer event or the possibility of maintenance of the mt copy for specialized functional regulation during different developmental stages. (Abstract shortened by UMI.)
Dobbelt op på jernbanen med store projekter
Creators: name: Landex, Alex
name: Zibrandtsen, Bastian
name: Jensen, Tommy O.
name: Wahlsten, Bjørn
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2012

description: Stikordsreferat fra Trafikdage i Aalborg, 27. august 2012
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2012): Proceedings from the Annual Transport Conference at Aalborg University
Novel Tactile Sensor Technology and Smart Tactile Sensing Systems: A Review
Creators: name: Zou, Liang
name: Ge, Chang
name: Wang, Z. Jane
name: Cretu, Edmond
name: Li, Xiaoou
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: During the last decades, smart tactile sensing systems based on different sensing techniques have been developed due to their high potential in industry and biomedical engineering. However, smart tactile sensing technologies and systems are still in their infancy, as many technological and system issues remain unresolved and require strong interdisciplinary efforts to address them. This paper provides an overview of smart tactile sensing systems, with a focus on signal processing technologies used to interpret the measured information from tactile sensors and/or sensors for other sensory modalities. The tactile sensing transduction and principles, fabrication and structures are also discussed with their merits and demerits. Finally, the challenges that tactile sensing technology needs to overcome are highlighted.
GRB 090426: The environment of a rest-frame 0.35-s gamma-ray burst at a redshift of 2.609
Creators: name: Levesque, Emily M.
name: Bloom, Joshua S.
name: Butler, Nathaniel R.
name: Perley, Daniel A.
name: Cenko, S. Bradley
name: Prochaska, J. Xavier
name: Kewley, Lisa J.
name: Bunker, Andrew
name: Chen, Hsiao-Wen
name: Chornock, Ryan
name: Filippenko, Alexei V.
name: Glazebrook, Karl
name: Lopez, Sebastian
name: Masiero, Joseph
name: Modjaz, Maryam
name: Morgan, Adam
name: Poznanski, Dovi
Publisher: name: Swinburne
Year: 2024

description: We present the discovery of an absorption-line redshift of z= 2.609 for GRB 090426, establishing the first firm lower limit to a redshift for a gamma-ray burst (GRB) with an observed duration of <2 s. With a rest-frame burst duration of T90z= 0.35 s and a detailed examination of the peak energy of the event, we suggest that this is likely (at >90 per cent confidence) a member of the short/hard phenomenological class of GRBs. From analysis of the optical-afterglow spectrum we find that the burst originated along a very low H i column density sightline, with NH i < 3.2 × 1019 cm−2 . Our GRB 090426 afterglow spectrum also appears to have weaker low-ionization absorption (Si ii, C ii) than ∼95 per cent of previous afterglow spectra. Finally, we also report the discovery of a blue, very luminous, star-forming putative host galaxy (∼2L*) at a small angular offset from the location of the optical afterglow. We consider the implications of this unique GRB in the context of burst duration classification and our understanding of GRB progenitor scenarios.
Forretningsudvikling i havne
Creators: name: Henriques, Michael
name: Juhl, Birgitte
name: Kettler, Mogens
name: Olesen, Peter
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2012

description: Stikordsreferat fra Trafikdage i Aalborg, 27. august 2012
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2012): Proceedings from the Annual Transport Conference at Aalborg University
Interleukin-18 Mediates Immune Responses to Campylobacter jejuni Infection in Gnotobiotic Mice
Creators: name: Bereswill, Stefan
name: Alutis, Marie E.
name: Grundmann, Ursula
name: Fischer, Andre
name: Göbel, Ulf B.
name: Heimesaat, Markus M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Human Campylobacter jejuni infections are progressively rising worldwide. Information about the molecular mechanisms underlying campylobacteriosis, however, are limited. In the present study we investigated whether cytokines such as IL-23, IL-22 and IL-18, which share pivotal functions in host immunity, were involved in mediating intestinal and systemic immunopathological responses upon C. jejuni infection. Methodology/Principal Findings To assure stable infection, gnotobiotic (i.e. secondary abiotic) IL- 23p19-/-, IL-22-/- and IL-18-/- mice were generated by broad-spectrum antibiotic treatment. Following peroral C. jejuni strain 81–176 infection, mice of all genotypes harbored comparably high pathogenic loads in their intestines. As compared to wildtype controls, however, IL-18-/- mice displayed less distinct C. jejuni induced sequelae as indicated by less pronounced large intestinal shrinkage and lower numbers of apoptotic cells in the colonic epithelial layer at day 8 postinfection (p.i.). Furthermore, lower colonic numbers of adaptive immune cells including regulatory T cells and B lymphocytes were accompanied by less distinct secretion of pro-inflammatory cytokines such as TNF and IFN-γ and lower IL-17A mRNA expression levels in colonic ex vivo biopsies of infected IL-18-/- as compared to wildtype mice. Upon C. jejuni infection, colonic IL-23p19 expression was up-regulated in IL-18-/- mice only, whereas IL-22 mRNA levels were lower in uninfected and infected IL-23p19-/- as well as infected IL-18-/- as compared to respective wildtype control mice. Remarkably, not only intestinal, but also systemic infection-induced immune responses were less pronounced in IL-18-/- mice as indicated by lower TNF, IFN-γ and IL-6 serum levels as compared to wildtype mice. Conclusion/Significance We here show for the first time that IL-18 is essentially involved in mediating C. jejuni infection in the gnotobiotic mouse model. Future studies need to further unravel the underlying regulatory mechanisms orchestrating pathogen-host interaction.
Dynamiske effekter af infrastrukturinvesteringer
Creators: name: Christensen, Anette
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2012

description: Referat af special session ved Trafikdage 2012
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2012): Proceedings from the Annual Transport Conference at Aalborg University
A matter of consciousness : personal identity in the writings of Anna Barbauld, 1743-1825.
Creators: name: Ready, Kathryn (Kate).
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Literature, English.

description: My thesis explores the issue of personal identity in the literary career of Anna Laetitia Barbauld (1743--1825), situating her within the context of contemporary debate over the nature of identity and the self, first initiated by John Locke in the second edition of An Essay concerning Human Understanding (1694), and his contention "that self is not determined by Identity...of Substance...but only by Identity of consciousness" (2.27.23). The term substance first appears in Aristotle's definition of man as a vital union of matter and substance, a definition later absorbed into the Christian view of man as a vital union of body and soul, or material and immaterial substance. Without denying the existence of substance, Locke considers it an inadequate foundation for a theory of personal identity. As he argues, substance is beyond the scope of human knowledge, and therefore cannot assure us of the continuity of the self. Only our knowledge of consciousness can give us confidence in the continuity of the self. Chapter one presents evidence of Barbauld's interest in the debate over personal identity, followed by a detailed account of Locke's theory of self-in-consciousness, and a discussion of its implications with respect to both class and gender. Chapter two traces the history of Barbauld's engagement in the debate over personal identity. As I argue, Barbauld gradually adopts Locke's position on identity, while still upholding the essential truth of the orthodox Christian view of the self. Chapters three and four investigate the way in which Barbauld's simultaneous endorsement of the theories of self-in-consciousness and self-as-substance informs both her political and feminist ideology. In chapters five, six, and seven, I examine how the complex legacy of Locke's theory of personal identity influences the progress of Barbauld's literary career, as she draws upon it to consolidate her position as a woman writer, and to develop her aesthetic theory.
Indspil til Trængselskommissionen
Creators: name: Christensen, Anette
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2012

description: Referat af Special Session 'Indspil til Trængselskommissionen' ved Trafikdage 2012
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2012): Proceedings from the Annual Transport Conference at Aalborg University
EEG
Creators: name: Domke, Friederike
name: Marty, Michael
Publisher: name: Nomos
Year: 2020
Subjects: Erneuerbare-Energien-Gesetz
Bundesrepublik Deutschland

description: Das Gesetz für den Ausbau erneuerbarer EnergienÌ® stellt mit der gesetzgeberischen Kompromissformel eines ćharmonisierten ZubausÌ® vollkommen neue Herausforderungen an Juristen, Verbände, Anlagenbetreiber und -hersteller, Kommunen und nicht zuletzt die Wirtschaft. Der neue EEG-Handkommentar konzentriert sich aus Beratersicht auf die komplizierten Neuregelungen und bindet bereits die ersten Gerichtsentscheidungen nach der EEG-Novelle ein. Er bereitet anschaulich die typischen Problemlagen praxisgerecht auf: Gibt es Übergangsregelungen? Welche Regelungen gelten für Altanlagen? Wie verhält es sich mit der bisherigen Rechtsprechung und den Entscheidungen der Clearingstelle EEG? Wie werden die Förderkosten künftig verteilt? Wann wird die Eigenversorgung überhaupt noch privilegiert? Welche Anlagenbetreiber müssen ihren Strom ab wann direkt vermarkten? Welche Anlagenbetreiber müssen EEG-Umlage bezahlen und in welcher Höhe? Welche stromintensiven Unternehmen können die Besondere Ausgleichsregelung weiterhin für sich in Anspruch nehmen? Was ist zu beachten bei den aktuellen Pilotausschreibungen für PV-Freiflächenanlagen? Herausgeber und Autoren mit langjähriger Beratungserfahrung gewährleisten den schnellen Zugriff auf anwendungsorientierte Lösungen neuer Rechtsfragen nach der Reform: RA Toralf Baumann, RA Guido Brucker, RA Dr. Dominik Greinacher, RA Dr. Reinald Günther, Dr. Andrea Huber, RAin Dr. Jule Martin, Michael Marty, Dr. Christoph Maurer, Dr. Marike Pietrowicz, René Walter. Quelle: Verlagsinformation
title: What you see is what you get
title: a closer look at bias in the visual world paradigm
titleType: Subtitle
Creators: name: Nolte, Collin
Publisher: name: University of Iowa
Year: 2024
Subjects: bdots
eye-tracking
time series
VWP
public abstract
Cognitive Psychology

description: In 1995 the Visual World Paradigm was first introduced as an experimental paradigm relating eye-tracking data to lexical activation. This was done by measuring the location of a participant's visual fixation in real time in response to a spoken word. Shortly following this was the introduction of the ``proportion of fixations" method, whereby indicators of fixations in the VWP were aggregated across trials at dense time slices, creating an ostensible curve demonstrating the proportion of trials in which participants were fixated on particular objects at each time. In 2017, methods were introduced to make temporal analysis of these curves tractable via bootstrapping and a novel alpha correction to counteract the multiple comparison problems implicit in densely sampled time series.
description: This dissertation improves upon the field in multiple ways. First, we reintroduce the bdots package with a dramatically simplified user interface. Most prominent among these changes include the ability for users to create and fit parametric functions independent the bdots software as well as the introduction of permutation testing for identifying temporal differences between groups. We also identify and correct methodological issues found in the original bootstrapping algorithm that, when unaccounted for, potentially lead to family-wise error rates of over 90%. Both this correction and the newly introduced permutation test demonstrate quality maintenance of the FWER across a robust collection of underlying assumptions without significant losses in power.
description: And finally, we propose a new generative model that links eye mechanics to lexical activation, along with a novel ``look onset" method that seeks to replace the proportion of fixations method. We demonstrate asymptotic consistency between our generative model and the look onset method, both with regards to the recovery of subject-specific activation curves, as well as with the identification of systematic temporal differences between groups. We conclude by demonstrating this utility with data collected from prior studies as well as by providing a number of avenues for future research.
XMS and NG1dF: Extreme multiplex spectrographs for wide-field multi-object spectroscopy
Creators: name: Content, Robert
name: Barden, Sam
name: Becerril, Santiago
name: Boehm, Armin
name: Clark, Paul
name: Costillo, Pedro
name: Dubbeldam, C. Mark
name: Farrell, Tony
name: Glazebrook, Karl
name: Haynes, Roger
name: Meisenheimer, Klaus
name: Miziarski, Stan
name: Nikoloudakis, Nikolaos
name: Prada, Luis Francisco
name: Rohloff, Ralf Rainer
name: Shanks, Tom
name: Sharples, Ray M.
name: Wagner, Karl
name: McLean, Ian S.
name: Ramsay, Suzanne K.
name: Takami, Hideki
Publisher: name: Swinburne
Year: 2024

description: Abstract not reproduced here by request of the publisher. The text is available from http://dx.doi.org/10.1117/12.857932
The 'anaphase problem': how to disable the mitotic checkpoint when sisters split
Creators: name: Vázquez-Novelle, María Dolores
name: Mirchenko, Lesia
name: Uhlmann, Frank
name: Petronczki, Mark
Publisher: name: The Francis Crick Institute
Year: 2024
Subjects: classificationCode: Biochemistry & Proteomics
subject: Biochemistry & Proteomics
classificationCode: Cell Cycle & Chromosomes
subject: Cell Cycle & Chromosomes
classificationCode: Computational & Systems Biology
subject: Computational & Systems Biology
classificationCode: Genetics & Genomics
subject: Genetics & Genomics
classificationCode: Model organisms
subject: Model organisms

description: Two closely connected mechanisms safeguard the fidelity of chromosome segregation in eukaryotic cells. The mitotic checkpoint monitors the attachment of kinetochores to microtubules and delays anaphase onset until all sister kinetochores have become attached to opposite poles. In addition, an error correction mechanism destabilizes erroneous attachments that do not lead to tension at sister kinetochores. Aurora B kinase, the catalytic subunit of the CPC (chromosomal passenger complex), acts as a sensor and effector in both pathways. In this review we focus on a poorly understood but important aspect of mitotic control: what prevents the mitotic checkpoint from springing into action when sister centromeres are split and tension is suddenly lost at anaphase onset? Recent work has shown that disjunction of sister chromatids, in principle, engages the mitotic checkpoint, and probably also the error correction mechanism, with potentially catastrophic consequences for cell division. Eukaryotic cells have solved this 'anaphase problem' by disabling the mitotic checkpoint at the metaphase-to-anaphase transition. Checkpoint inactivation is in part due to the reversal of Cdk1 (cyclin-dependent kinase 1) phosphorylation of the CPC component INCENP (inner centromere protein; Sli15 in budding yeast), which causes the relocation of the CPC from centromeres to the spindle midzone. These findings highlight principles of mitotic checkpoint control: when bipolar chromosome attachment is reached in mitosis, the checkpoint is satisfied, but still active and responsive to loss of tension. Mitotic checkpoint inactivation at anaphase onset is required to prevent checkpoint re-engagement when sister chromatids split.
Landstrafikmodellen i anvendelse
Creators: name: Stemmann, Ute
name: Brems, Camilla Riff
name: Filges, Dorte
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2012

description: Referat Trafikdage Aalborg Universitet august 2012
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2012): Proceedings from the Annual Transport Conference at Aalborg University
Explaining male inmate victimization in Canadian federal penitentiaries: A test of importation and deprivation theories.
Creators: name: Swait, Michael.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Sociology, Criminology and Penology.

description: Our understanding of criminal victimization in Canadian penitentiaries is quite limited because little research has been conducted in relation to this phenomenon. As a result, it is quite difficult to determine with any degree of certainty the true extent of inmate victimization in Canada. This paper examines the occurrence of victimization in Canadian penitentiaries to shed light on this phenomenon. Using information derived from the 1995 National Inmate Survey (N = 4,381 male federal inmates), the thesis examines the prevalence of inmate victimization in our federal penitentiaries and its relationship to a variety of institutional and individual indicators, as well as testing the relative usefulness of the importation and deprivation theories in explaining the patterns observed. Instances of physical assaults, assaults with weapons, sexual assaults, staff assaults, and gang activity show that violent behaviors are a fairly common occurrence in federal correctional institutions. Bivariate and multivariate analyses revealed some support for the existence of a relationship between institutional and individual indicators with inmate victimization in Canadian federal penitentiaries. Theoretical and policy implications of the data are suggested.
CULTURAL INFLUENCES ON COLOR MEANINGS AND USAGE IN ENGLISH AND RUSSIAN.
Creators: name: Bazarbayeva, Albina
name: Yunusova, Yulduz
Publisher: name: Zenodo
Year: 2024

description: The paper explores the ways in which Russian and English use and understanding of colour is affected by historical and cultural influences. It illustrates how colour symbolism, which shows in specific metaphorical and symbolic expressions linked to social, political, and religious views, has been moulded by the two languages' divergent historical and cultural histories.The meanings and linguistic usage of colours are shaped by the cultural and historical influences of each community. Colours not only reflect sensory perceptions but can stand for societal norms, political ideologies, religious convictions, and cultural values. Understanding these influences in both languages shows how language represents speakers' worldviews and makes it easier to grasp color-based expressions.