cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Bioinformatics and network pharmacology analysis of DWYG capsule for improving liver regeneration: identification of active compounds and mechanisms
Creators: name: Zhang, Chengyi
name: Xia, Shuang
name: Yan, Miao
name: Luo, Fen
name: Zhang, Bikui
name: Zou, Wei
name: Gong, Hui
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Computational Biology

description: Aimed to explore the mechanisms and targets of Diwu Yanggan Capsule (DWYG), a traditional Chinese medicine in liver regeneration, we used the TCMSP to obtain the active ingredients and targets of DWYG and the GEO database to obtain the DEGs related to liver regeneration. We also searched for liver regeneration-related genes in disease databases and integrated them with the herbal and GEO data to screen for potential targets of DWYG in liver regeneration. Enrichment analysis using R language and molecular docking of the key targets and active ingredients were constructed. We found 73 potential targets of DWYG in liver regeneration and revealed that DWYG may act through pathways such as MAPK, TNF, and IL-17. We also found that quercetin was a major component of DWYG with low binding energy to three key targets. Our results suggest that DWYG can facilitate liver regeneration and quercetin may be its core ingredient.
A rare phytosterol, stigmast-5-en-3β,7α,22α-triol and other secondary metabolites from Leea indica showing enhanced in vitro cell migration and proangiogenic activity
Creators: name: Samarasinghe, W. M. Priyantha
name: Ranasinghe, Chandani
name: Jayawardana, K. Hector
name: Somaratne, Seneviratnage
name: Gunaherath, G. M. Kamal B.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Leea indica (Burm. f.) Merr. (Vitaceae) is used for the treatment of wounds in traditional medicine practiced in Sri Lanka. The current study is carried out to investigate its wound healing potential in terms of in vitro cell migration and proangiogenic activity. The scratch wound assay (SWA) guided fractionation of dichloromethane extract of L. indica led to the isolation of a rare phytosterol, stigmast-5-en-3β,7α,22α-triol (1), betulin (2), lupeol (3), and β-sitosterol (4) all of which showed enhanced cell migration in SWA and significant proangiogenic response in chorioallantoic membrane (CAM) assay. The identities of compounds 1–4 were established by the analysis of NMR spectroscopic data and comparison with those reported. This is the first report of the occurrence of compounds 1 and 2 in L. indica.
Nymphaea nouchali var. caerulea Verdc.
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Nymphaeales
Nymphaeaceae
Nymphaea
Nymphaea nouchali
Nymphaea nouchali var. caerulea (savigny) verdc.

description: Nymphaea nouchali var. caerulea (Savigny) Verdc.
Bas.: Nymphaea caerulea Savigny
Perennial herb, in pond and river beds, and forest galleries.
C.N.: mandabole, munganje (kb).
Uses: food, medicinal.
Conservation: EN (IUCN 2017)
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Drug designing and toxicity screening of halogen and nitrogen-augmented catechin in sarcopenic obesity
Creators: name: Sabarathinam, Dr Sarvesh
name: Satheesh, Sanjana
name: Ganamurali, Nila
name: Dhanasekaran, Dhivya
name: Raja, Arun
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: In this study, the catechin structure was modified with Halogen and Nitrogen base at C-6 and C-8 Positions in Ring A. Pharmacokinetic parameters affirm the drug-likeness property of the designed compounds. Molecular Docking was performed for all the compounds towards the myostatin inhibition target (PDB: 3HH2). Such desirable quality of modified Catechin will create a spark in the novel drug discovery using acting as a bioenhancer. As a result, the present research is aimed to offer an overview of the structural simulation of Cl, F, I, NH2, NO2, and Br at C-6 and C-8 positions in A Ring A of Catechin. This preliminary evidence creates an impact on the novelsemi0synthetic drug discovery for the therapeutic management of sarcopenia.
Protease inhibitors characterisation by SDS-PAGE and MALDI-TOF from Alocasia macrorrhizos and their modulation of macrophage immune-inflammatory properties
Creators: name: Cordeiro, Isac H.
name: Lima, Nerilson M.
name: Scherrer, Elaine C.
name: Carli, Gabriela P.
name: de Jesus A. S. Andrade, Teresinha
name: Castro, Sandra B. R.
name: de Oliveira, Marcone A. L.
name: Alves, Caio Cesar S.
name: Carli, Alessandra P.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: This study describes the extraction and identification by electrophoretic and spectrometric techniques of protease inhibitor from the medicinal plant Alocasia macrorrhizos as well as investigates their immunomodulatory properties and cell viability. The A. macrorrhizos tubers were subjected to protease inhibitor extractions and characterised using SDS-PAGE and MALDI-TOF. The protein extracts were assessed for activities trypsin inhibition stoichiometry, haemagglutinating, cell viability, NO and TNF-α production inhibition. Concerning the protease inhibitors analysis through SDS-PAGE, the results showed two bands with 11 and 24 kDa, and the MS analysis detected the ions more intense of m/z 4276.795 and 8563.361 in the roasted protein extract. The IC50 of trypsin inhibition was 0.119 and 0.302 mg L−1 in the roasted and crude tuber, respectively. The protease inhibitors extract from the roasted tubers showed a reduction in the production of NO and TNF-α at concentrations lower than 100 µg mL−1, without a reduction in cell viability.
Inulin as prebiotic encapsulating agent for the production of spray-dried Hibiscus sabdariffa L. tea microcapsules
Creators: name: Calliari, Caroline Maria
name: Shirai, Marianne Ayumi
name: Casazza, Alessandro Alberto
name: Pettinato, Margherita
name: Perego, Patrizia
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: Due to the high content of phenolics and anthocyanins of Hibiscus sabdariffa L. tea and the sensibility of these bioactive compounds, this work aimed to optimize the obtention of microcapsules by spray-drying, using inulin as a carrier agent. Using a Box-Behnken Design, the effects of inlet temperature (130, 150, and 170 °C), feed flow rate (5, 10, and 15 mL min−1), and inulin concentration (5, 10, and 15 g L−1) were evaluated. It was possible to obtain pale-rose, slightly sweet instant powders with good total polyphenol content (1.12 mgGAE g−1) and anthocyanins encapsulation efficiency (32.3–60.6%), besides moisture (4.61–17.79%) and water activity (0.221–0.501), indicating physico-chemical and microbiological stability of the microcapsules. A simultaneous optimization with the desirability function was performed to maximize all the response variables analyzed, and the optimum conditions of 5 g L−1 of inulin, inlet temperature of 170 °C, and feed flow rate of 83 mL min−1 were found.
Commicarpus plumbagineus Standl.
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Nyctaginaceae
Commicarpus
Commicarpus plumbagineus

description: Commicarpus plumbagineus (Cav.) Standl.
Bas.: Boerhavia plumbaginea Cav.
Prostrate or climbing perennial herb, in wooded savannah, open forest, forest galleries, thicket, and grassy savannah; also in cropland, fallow and disturbed sites.
C.N.: ditumbate, tumbate (kb).
Uses: medicinal.
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on pages 42-43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Anti-infective potential of the endophytic fungus Aspergillus sp. associated with Aptenia cordifolia root supported by metabolomics analysis and docking studies
Creators: name: Yousef, Miram Magdy
name: Abdelhafez, Omnia Hesham
name: Alsenani, Faisl
name: Al Mouslem, Abdulaziz K.
name: Hisham, Mohamed
name: Zawily, Amr El
name: Glaeser, Stefanie P.
name: Kämpfer, Peter
name: Abdelmohsen, Usama Ramadan
name: El-Katatnye, Mo’men Hamed
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Endophytic fungi are known to be a rich source for anti-infective drugs. In this study, Aptenia cordifolia associated endophytic fungi were explored for the first time. Seven isolates were identified morphologically followed by screening of these fungi by plug diffusion assay which revealed their potential activity against Staphylococcus aureus (ATCC 9144), Bacillus cereus (ATCC 14579), Serratia marcescens (ATCC 14756), Fusarium oxysporum (ATCC 48112), and Aspergillus flavus (ATCC 22546). Additionally, the crude ethyl acetate extract of the most potent three isolates in plug diffusion assay showed that Aspergillus sp. ACEFR2 was the most potent as anti-infective in disc diffusion assay; Accordingly, Aspergillus sp. ACEFR2 was investigated using phylogenetic analysis and LC-HR-ESI-MS. The phylogenetic analysis placed the strain into the Aspergillus section Niger close related to few species including A. niger. Whereas the metabolomic profiling revealed the presence of diverse pool of metabolites. Furthermore, in silico molecular docking study was carried out to predict which compounds most likely responsible for the anti-infective activity.
Ximenia americana L.
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Santalales
Ximeniaceae
Ximenia
Ximenia americana

description: Ximenia americana L.
Shrub, in wooded savannah, open forest, thicket, grassy savannah; also on fallow and disturbed sites.
C.N.: mudiahongo, muinge, muginge, muienge, muhinji, mukuinji (kb).
Uses: firewood, food, medicinal.
Conservation: LC (IUCN 2017)
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Ximenia caffra Sond.
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Santalales
Ximeniaceae
Ximenia
Ximenia caffra

description: Ximenia caffra Sond.
Syn.: Ximenia americana var. caffra (Sond.) Engl.
Shrub, in wooded savannah, thicket, and grassy savannah.
Source: Adão (2017)
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Validation of the Arabic linguistic version of the Overactive Bladder Symptoms Score questionnaire
Creators: name: Elbaset, M. A.
name: Hashem, Abdelwahab
name: Taha, Diaa-Eldin
name: Zahran, Mohamad H.
name: El-Hefnawy, Ahmed S.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Objective: To validate an Arabic version of the Overactive Bladder Symptom Score (OABSS) questionnaire. Patients and methods: In all, 301 patients were evaluated using the Arabic-translated OABSS. They were divided into four groups: 112 patients with OAB symptoms, 115 healthy individuals with no OAB symptoms, 38 with bladder outlet obstruction (BOO) associated with storage lower urinary tract symptoms (LUTS), and 36 with BOO without storage LUTS. The reliability of the Arabic version was evaluated for internal consistency using Cronbach’s α test. Interdomain associations were examined using Spearman’s correlation coefficient (r). The discrimination validity was evaluated using the Mann–Whitney test. Results: Higher internal consistency was found for all OABSS domains in the OAB and BOO groups. There were strong correlations between all domains in the OAB group (P < 0.001). Similarly, there were strong correlations between all domains in the BOO group. For discrimination validity, scores were statistically significant higher for all OABSS domains and overall total scores in the OAB and BOO groups compared with their control groups (P < 0.001). Conclusion: The Arabic version of OABSS is a reliable and valid instrument that can be used to evaluate symptoms and health-related quality of life in Arabic patients with OAB. Clinical trial no. (clinicaltrials.gov NCT03533062) Abbreviations : BOO: bladder outlet obstruction; OAB: overactive bladder; OABSS: Overactive Bladder Symptom Score questionnaire; (U)UI: (urgency) urinary incontinence
Spontaneous urban vegetation on its way to green walls
Creators: name: Caregnato, Susanna
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Biodiversity
Urban vegetation
Wall vegetation
Green wall
Living wall
Biodiverse wall
333.7: Landflächen, Naturerholungsgebiete

description: Allowing spontaneous urban vegetation to grow on building facades directly could represent a valuable alternative to current common green walls on building, from a cost and maintenance but also biodiversity perspective. The aim of this work is first to document characteristics of the sprouting points of plants on walls. Secondly, with the analysis of the recorded data, possible preferred structures shall be determined to be able to draw conclusions about germination and growth fostering design of construction elements for building facades. The work covers spontaneous vegetation growing on freestanding walls, retainment walls or walls of buildings and civil constructions in Zurich, Switzerland. The wall tops, vertical wall surfaces and wall base joints are assessed separately. With statistical methods (linear models) various environmental characteristics of the walls are examined for significant influence on species richness and cover or abundance. Further, quantitative evaluation of different characteristics of the sprouting Species cover on vertical wall surfaces is significantly positively influenced by inclination in interaction with distance from the ground of the plot and seldom maintenance. Plants use all different forms of sprouting points, i.e., joints, cracks, pores, the substantial difference in occurrence of plants in these different forms is mainly due their highly different occurrence on walls and not to a preference of the plants. Finally, water provision is the most critical point for successful facade vegetation on buildings. To realize a good water provision on facades for plants two options could be considered in future architectural designs of facades: 1. build facade with inclination over 10°; 2. Integrate rainwater flow and water retainment in the facade elements.
Jasminum angolense Baker
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Oleaceae
Jasminum
Jasminum angolense

description: Jasminum angolense Baker
Climbing or prostrate shrub, in wooded savannah, grassy savannah, open forest, and thicket; also in disturbed sites. C.N.: kalokolo-demii (kb).
Uses: medicinal.
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
In vitro and in silico studies of antibacterial activities of secofriedelane derivatives from Senna alata (L) Roxb
Creators: name: Chimi, Simplice F.
name: Ewonkem, Monique B.
name: Tiakouang, Eunice N.
name: Moto, Jean O.
name: Adjieufack, Abel I.
name: Deussom, Pascaline M.
name: Mbock, Michel A.
name: Wansi, Duplex J.
name: Toze, Alfred F. A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: In this study, six compounds were obtained from a methanolic extract of air-dried leaves of Senna alata and one of them, a triterpenoid (secofriedelane) named as 7-(2-carboxyethyl)-3, 4b, 6a, 8, 10a, 12a-hexamethyl-8-vinyloctadecahydrochrysene-3-carboxylic acid (5) was isolated for the first time from this plant. Then, its chemical structure was detailed and characterised by FT-IR, 1H and 13C- NMR and ESI-MS. Besides, two chemical-modified derivatives of secofriedelane (5a, 5b) were synthesised by methylation and allylation reactions, respectively, and their in vitro antibacterial activities were also evaluated. The results revealed that all the triterpenes showed, against gram-positive and -negative bacterial strains, good and moderate antibacterial activities with bactericidal effects that were enhanced by the methyl groups and altered with the allyl ones. Moreover, the molecular docking results of 5, 5a and 5b in the DNA gyrase (2XCT) active site showed that triterpene 5 has a good score very close to reference (ciprofloxacin).
Data use and interoperability for ecological and spatial oriented design
Creators: name: Balducci, Andrea
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Sustainable development
Sustainable building
Urban ecology
Biodiversity
Holistic design
Design with Nature
Ecological oriented design
Revit
Parametric design
Integrated biodiversity measure design
333.7: Landflächen, Naturerholungsgebiete
577: Ökologie

description: Fragmentation, degradation, and loss of habitats have caused serious loss of biodiversity. Urbanization especially is exerting an increased social, health, infrastructural and environmental pressure on urban ecosystems. In fact, the eco-logical footprint of urban areas is set to increase in the coming decades, additionally exacerbated by the effects of climate change. While urbanization and the expansion of the built environment have currently a negative impact on biodiversity, they also represent the greatest opportunity to integrate the promotion of biodiversity into development projects. This is an opportunity to be grasped by the AEC industry to design integrated eco-services and to eco-retrofit our cities, as well as to actively integrate biodiversity conservation into urban planning processes. At the same time, there is still uncertainty on what could be the drivers and incentives for planners and architects to implement such ecological and spatial oriented designs. There is a need of a new way of integrating ecological knowledge early in the design processes, that is focused more on interdisciplinary cooperation and on the integration in the built environment of biodiversity and wildlife inclusive sensitive designs. This thesis investigates the interdisciplinary cooperation and the ecological data interoperability, by seeking opinions of the AEC sector workers, teachers and students, through an online questionnaire about the awareness and readiness towards adopting sustainable and most importantly ecological and biodiversity improving project designs. Furthermore, it investigates the feasibility of developing, through parametric design, a façade integrated target species promoting BIM element. The modeling and parametrization were developed using Revit Architecture, a popular BIM software, whereas Dynamo, a visual programming environment, was used to test the interaction capabilities of such element in relation with its parameters and the ecological information. This thesis is intended, on one hand to improve the interdisciplinary exchange and understanding of ecological information and on the other to explore a way of creating a façade integrated BIM element, that can be adapted and modified in real time in correlation with the dimensions of a selected target species. Thereby providing ecologists, architects and planners with the knowledge and tools to maximize cooperation and the biodiversity potential of their designs.
Open Educational Resources (OER) in der digitalen Hochschullehre
Creators: name: Flühler, Roger
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: OER
Open Educational Resource
Bibliothek
Bildung
Nachhaltigkeit
Pädagogik
Sustainable Development Goal
378: Hochschulbildung

description: Wo nicht anders genannt, steht dieses Poster unter der Lizenz CC BY 4.0.
Jasminum fluminense Vell.
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Oleaceae
Jasminum
Jasminum fluminense

description: Jasminum fluminense Vell.
Climbing shrub, in wooded savannah, open forest, thicket, and grassy savannah; also in fallow and disturbed sites.
C.N.: kalokolo-demii (kb).
Uses: medicinal.
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
SAMARQAND VILOYATINING SUG'ORILADIGAN BIOTSENOZLARIDA QORAMOLLARNING PARENXIMATOZ ORGANLARINING ASOSIY GELMINTOZLARI
Creators: name: Nurmamadov T.E. – talaba Urokov K.X. – ilmiy rahbar- v.f.f.d. PhD
Publisher: name: Zenodo
Year: 2024

description: Maqolada Samarqand viloyatining sug‘oriladiganbiotsenozlarida kasallikdan o‘lgan, majburiy yoki go‘sht maxsuloti uchun so‘yilgan182 bosh qoramol to‘liq gelmintologik yorib ko‘rish usuli bilan hamda 1594 boshqoramol tirikligida gelmintokoprologik usullar bilan tekshirilib qoramollarningasosiy parenximatoz organlarining epizootologiyasi o‘rganilgan.
Vegetation and soil microbial diversity along alpine elevation and snow gradients
Creators: name: Keller, Sabrina
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Alpha diversity
Alps
Drivers
Elevation gradient
PH
Plants
Microbes
rRNA sequencing
Species richness
Snow gradient
Structural equation model SEM
579: Mikrobiologie
580: Pflanzen (Botanik)

description: Along elevation gradients, effects of changing environmental conditions can be observed and predicted, with plants being commonly used as bioindicators. The relationship between plant alpha diversity and elevation depends on the sampling design and shows unimodal or decreasing patterns, whereas there are inconsistent or even contradictory findings for soil microbes (bacteria, fungi, protists). I examined plant and microbial diversity indices (species richness, Shannon index, Shannon evenness index) along alpine elevation and snow gradients in Switzerland, using the snow gradient to represent seasonal variation and soil moisture. To determine the effect of both gradients on diversity indices and test their relationship, I conducted linear mixed-effect models (LME) and correlation tests. In structural equation models (SEM), I examined the (in-) direct effect of elevation and snow gradient, pH, and plant species richness on microbial diversity. All diversity indices of plants and microbes showed a unimodal relationship along the elevation gradient, while species richness of fungi was influenced by the interaction of both gradients and showed increasing and decreasing linear patterns along the snow gradient. The species richness of protists showed no relationship with elevation but was highest in plots under snow cover. I could not detect an effect of plant species richness on microbial diversity indices in the SEM. Both gradients, as well as pH, had shown a direct influence, whereby their effects differed between microbial groups and indices. Even though plant species richness did not significantly affect microbial diversity in my analyses, at least a link between plant and bacterial diversity is to be expected, because they follow the same unimodal curve and are positively correlated. Thus, further research is needed, for example based on functional groups, to explore these relationships.
Ludwigia stenorraphe H. Hara
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Myrtales
Onagraceae
Ludwigia
Ludwigia stenorraphe

description: Ludwigia stenorraphe (Brenan) H.Hara
Bas.: Jussiaea stenorraphe Brenan
Perennial herb or subshrub, in river and lake shores.
F.Monteiro 537 (LUAI, LISC)
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 44, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Auswirkungen der Beregnung auf die Trockenvegetation in der Gemeinde Bettmeralp (VS)
Creators: name: Schindler, Meret
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Auswirkungen
Bewässerung mit Sprinkler
Biodiversität
Gefässpflanzen
ökologische Zeigerwerte
Trockenwiesen
Trockenweiden
Vegetationsveränderungen
Wallis
Wiederholungsaufnahmen
333.7: Landflächen, Naturerholungsgebiete
580: Pflanzen (Botanik)

description: Halbtrockenrasen gehören zu den artenreichsten anthropogenen Lebensräumen der Gefässpflanzen in der Paläarktis. Jedoch ist in den inneralpinen Trockentälern des Wallis die Bewässerung der Halbtrockenrasen oft eine Grundvoraussetzung für die Ertragssicherung. Da bisher nur wenige Studien die langfristigen Auswirkungen der Beregnung mittels Sprinkler untersuchten, wurden Wiederholungsaufnahmen auf 12 Untersuchungsflächen in der Gemeinde Bettmeralp durchgeführt. Zusätzlich wurden weitere Flächenpaare (bewässert/unbewässert) im Gemeindegebiet aufgenommen. Das Ziel war die Biodiversitätsindizes, ökologischen Zeigerwerte, Arten der Roten Liste und die Lebensräume der Untersuchungsflächen zu quantifizieren sowie diese mit einem gepaarten t-Test und einer Co-Varianzanalyse statistisch auszuwerten. Die Dauerflächen veränderten sich geringfügig von 1988 bis 2021. Zwei Flächen entwickelten sich in nährstoffreiche Bestände und die Humuszahl nahm signifikant zu. Die unbewässerten und bewässerten Flächen unterschieden sich signifikant bei der Artenzahl und 10 gewichteten Zeigerwerten, wobei die Hangneigung bei vier Zeigerwerte einen signifikanten Einfluss hatte. Diese Ergebnisse zeigen, welche Auswirkungen die Bewässerung und teilweise die Düngung auf die Trockenvegetation hat. Die geringen Veränderungen auf den Dauerflächen deuten daraufhin, dass die Böden noch von der traditionellen Bewässerung, welche in den 60er Jahre aufgegeben wurde, geprägt waren.
Protease inhibitors characterisation by SDS-PAGE and MALDI-TOF from Alocasia macrorrhizos and their modulation of macrophage immune-inflammatory properties
Creators: name: Cordeiro, Isac H.
name: Lima, Nerilson M.
name: Scherrer, Elaine C.
name: Carli, Gabriela P.
name: de Jesus A. S. Andrade, Teresinha
name: Castro, Sandra B. R.
name: de Oliveira, Marcone A. L.
name: Alves, Caio Cesar S.
name: Carli, Alessandra P.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: This study describes the extraction and identification by electrophoretic and spectrometric techniques of protease inhibitor from the medicinal plant Alocasia macrorrhizos as well as investigates their immunomodulatory properties and cell viability. The A. macrorrhizos tubers were subjected to protease inhibitor extractions and characterised using SDS-PAGE and MALDI-TOF. The protein extracts were assessed for activities trypsin inhibition stoichiometry, haemagglutinating, cell viability, NO and TNF-α production inhibition. Concerning the protease inhibitors analysis through SDS-PAGE, the results showed two bands with 11 and 24 kDa, and the MS analysis detected the ions more intense of m/z 4276.795 and 8563.361 in the roasted protein extract. The IC50 of trypsin inhibition was 0.119 and 0.302 mg L−1 in the roasted and crude tuber, respectively. The protease inhibitors extract from the roasted tubers showed a reduction in the production of NO and TNF-α at concentrations lower than 100 µg mL−1, without a reduction in cell viability.
Jasminum undetermined
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Lamiales
Oleaceae
Jasminum
Jasminum undetermined

description: Jasminum sp.
Climbing shrub, in wooded savannah, open forest, thicket, and grassy savannah; also fallow and disturbed sites.
C.N.: musosongo (kb).
Uses: medicinal.
F.Monteiro 601 (LUAI, LISC)
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 43, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Metabolomics analysis of Citrus medica var. sarcodactylis (Siebold ex Hoola van Nooten) Swingle and Limonia acidissima Linn. fruits and leaves in perspective to their antimicrobial potential
Creators: name: Sayed, Abeer M. El
name: El-Abd, Eman A. W.
name: Hashim, Fatma A.
name: Farid, Mohamed A.
name: Shata, Hoda M. A. H.
name: Hawary, Seham S. El
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Antimicrobial potential of Citrus medica var. sarcodactylis (Siebold ex Hoola van Nooten) Swingle and Limonia acidissima L. fruits and leaves extracts CMF, CML, LAF and LAL, respectively were evaluated. Gas chromatography–mass spectrometry (GC-MS) analysis for lipoidal matters revealed a high percentage of non-oxygenated compounds. Phytol was the major in LAL. Palmitic and linoleic acid were the major in CML and LAL, respectively. Rutin and P-hydroxy benzoic acid were the main compounds identified by High-performance liquid chromatography (HPLC) analysis. The antibacterial and antifungal activities of the plants extract were determined by the well diffusion method. Antimicrobial investigation for different successive fractions of active methanol extracts of CML, LAL, LAF and CMF showed the highest activity (CML), whereas the petroleum ether (CML PE) and MeOH (CML) fractions exhibit a significant antifungal activity against Candida albicans minimum inhibitory concentration (MIC) 12 and 15 µg/mL, respectively. The antifungal activity prevailed by C. medica leaves may be attributed to its polyphenolics (rutin, chlorogenic and rosmarinic acid) in addition to phenylated hydrocarbon.
Responsible Digital Innovation : zur Implementierung von digitalethischer Verantwortung in betrieblichen Innovationsprozessen
Creators: name: Ernst, Luis-Eduardo
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Responsible innovation
Digital ethics
Digital innovation
658.406: Innovationsmanagement, Change Management

description: Die Durchdringung von digitaler Technologie hat zu einer Beschleunigung von sozialen und wirtschaftlichen Prozessen geführt. Viele Unternehmen reagieren darauf mit schnelleren und effizienteren Innovationszyklen. Dabei geraten in den Innovationsprozessen Überlegungen zu den gesellschaftlichen Auswirkungen digitaler Technologien oft in den Hintergrund. Gleichzeitig erwartet die Gesellschaft von Unternehmen immer mehr Verantwortung in Bezug auf ihr ökologisches, soziales und wirtschaftliches Handeln. Eine Analyse des aktuellen Forschungsstands in den Themengebieten „Responsible Innovation“ und „Digitaler Ethik“ zeigte, dass tendenziell ein Mangel an Lösungsansägen und Konzepten für die Praxis besteht, die als konkrete Handlungsanweisungen zu verstehen sind, gleichzeitig (digital-)ethisch fundiert sind und den nötigen Betrachtungsumfang aufweisen. Das Ziel dieser Arbeit ist, diese Forschungslücke aus theoretischer und vor allem auch praktischer Sicht zu schliessen und einen Ansatz zu erarbeiten, der beantworten kann, wie sich eine digitalethische Verantwortung in betrieblichen Innovationsprozessen systematisch implementieren lässt. Das Forschungskonzept baut auf der Entwicklung eines theoretisch abgeleiteten Bezugsrahmens auf, der empirisch mittels einer qualitativen Befragung von Praxisexperten aus den Bereichen CSR und Innovation überprüft und zu einem finalen Rahmenmodell angereichert wird. Die vorliegende Arbeit kommt zum Schluss, dass bei der Implementierung von Ethik in der digitalen Innovation eine einseitige Sicht auf die operativen Innovationsprozesse zu kurz reicht. Zur Umsetzung wird eine integrierte dreifache Betrachtungsweise von Individuum (Innovatoren), Kultur der Organisation und organisatorischen Strukturen vorgeschlagen, um den epistemischen, moralpsychologischen und ethischen Anforderungen genügend Rechnung zu tragen. Als Handlungsempfehlung werden auf Basis der Ergebnisse folgende Schritte aufgezeigt, um verantwortungsvolle digitale Innovation in der betrieblichen Praxis umzusetzen: (1) die Etablierung eines ethischen Orientierungsrahmens, (2) die individuelle Befähigung der Innovatoren sowie (3) das Bereitstellen von Strukturen und Prozessen. Dieses Vorgehen lässt sich auf Innovations- und Digitalvorhaben in Unternehmen sowie Digitalfirmen übertragen.
Simple two-step purification and characterisation of peroxidase from Citrullus colocynthis
Creators: name: Ahmad, Malik Shoaib
name: Shah, Nayab
name: Akbar, Zeeshan
name: Khan, Tajwali
name: Ali, Arslan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Peroxidase is a biotechnologically important enzyme. The purification of peroxidase from the root of Citrullus colocynthis was carried out in a simple two-step process with maximum purity level. The sample was extracted in a high salt buffer, and the enzyme was partially purified with a Q-Sepharose anion exchange column. Final purification was carried out with HighLoad 16/600 Superdex G-75 column. The purified protein was analysed with SDS gel electrophoresis, which suggested a single band of approximately 35 kDa. Further, the enzyme was identified with the help of Mass spectrometric analysis using an ESI-QTOF Mass spectrometer. The study will be helpful for the isolation and its commercial uses in biotechnology.
Die Relevanz von Kultursensibilität in der Sozialen Arbeit am Beispiel von psychisch belasteten geflüchteten Personen
Creators: name: Johnson, Lynn Darley
Publisher: name: ZHAW Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: 305: Personengruppen (Alter, Herkunft, Geschlecht, Einkommen)
361: Sozialarbeit und Sozialhilfe

description: Das Thema Flucht erscheint in den Medien, der Politik sowie im Bereich der Sozialen Arbeit. Soziale Arbeit mit geflüchteten Personen bringt eine hohe thematische Komplexität mit sich. Zum einen sind geflüchtete Personen von psychischen Belastungen geprägt. Zum anderen haben sie kulturelle Vorstellungen und Werte, welche sie von ihrem Herkunftsland kennen und sich von jenen im Aufnahmeland unterscheiden können. Diese Faktoren können sich auf die Zusammenarbeit zwischen Sozialarbeitenden und der Klientel von psychisch belasteten geflüchteten Personen auswirken. 
Das Ziel der vorliegenden Arbeit ist es, am Beispiel von psychisch belasteten geflüchteten Personen zu beantworten, wie relevant Kultursensibilität in der Sozialen Arbeit ist. Aufgrund der thematischen Vielfalt gliedert sich die Hauptfrage in Teilfragen, die konkreter auf die Themenfelder der psychischen Gesundheit, der Kulturforschung und der interkulturellen Kompetenzen Bezug nehmen. 
Um die Fragestellungen zu beantworten, wurde eine Literaturarbeit, ergänzt durch ein Leitfaden-Interview für die Perspektive der Praxis, erarbeitet. Die psychische Gesundheit geflüchteter Personen wird ebenso dargelegt wie mögliche Belastungen vor, während und nach der Flucht. Weiter werden der Kulturbegriff und Kulturverständnisse aufgezeigt, insbesondere auch in Bezug zur Sozialen Arbeit. Darauf aufbauend werden verschiedene Kompetenzen im Umgang mit psychisch belasteten geflüchteten Personen erörtert. 
Die Beantwortung der Fragestellungen zeigte auf, dass eine Sensibilisierung von Sozialarbeitenden für die verschiedenen Differenzkategorien relevant ist. Dabei ist zu berücksichtigen, dass es falsch wäre, nur auf die Kategorie Kultur zu schliessen bei psychisch belasteten geflüchteten Personen. Denn dies würde zur Reproduktion von Kulturalisierung und Diskriminierung führen.
Phytochemical characterization and antifungal potential of leaf extracts of Mosiera bullata
Creators: name: Pérez-Gómez, Lianny
name: Pérez-Martínez, Aurora T.
name: Matheeussen, An
name: Pieters, Luc
name: Mendez, Daniel
name: Quirós-Molina, Yemeys
name: Trujillo, Reinaldo
name: Tuenter, Emmy
name: Cos, Paul
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: The investigation of natural alternatives to conventional fungicides is of imminent need. Mosiera bullata (Britton & P. Wilson) Bisse is a Cuban endemic plant species belonging to the Myrtaceae family. The objective of the present study was to perform a bioassay-guided fractionation to explore the potential of extracts and fractions from M. bullata leaves against a panel of fungal plant pathogens. The M. bullata total extract was confirmed to have good antifungal activity against R. oryzae (IC50 = 4.86 µg/mL) and moderate activity against F. oxysporum (IC50 = 352.40 µg/mL) and F. solani (IC50 = 427.38 µg/mL) and fungicidal effect against R. oryzae. Five compounds belonging to the class of phloroglucinol dimers were tentatively characterized by UHPLC-HRMS and reported for the first time in M. bullata and the genus Mosiera. These results suggest the potential of M. bullata total extract as a natural antifungal product for the control of diseases in agriculture.
Phyllanthus ovalifolius Forssk.
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Phyllanthaceae
Phyllanthus
Phyllanthus ovalifolius

description: Phyllanthus ovalifolius Forssk.
Syn.: Phyllanthus guineensis Pax
Subshrub, in open forest, thicket, and forest galleries.
C.N.: kasazangombe (kb); vassoura (pt).
Uses: artefacts.
Conservation: LC (IUCN 2017)
F.Monteiro 402 (LUAI, LISC)
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 44, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Ludwigia adscendens subsp. diffusa P. H. Raven
Creators: name: Monteiro, Francisca
name: Costa, Esperança Da
name: Kissanga, Raquel
name: Costa, José Carlos
name: Catarino, Luís
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Myrtales
Onagraceae
Ludwigia
Ludwigia adscendens
Ludwigia adscendens subsp. diffusa (forssk.) p.h.raven

description: Ludwigia adscendens subsp. diffusa (Forssk.) P.H.Raven
Bas.: Jussiaea diffusa Forssk.
Prostrate annual herb, in river and pond margins and beds.
description: Published as part of Monteiro, Francisca, Costa, Esperança Da, Kissanga, Raquel, Costa, José Carlos & Catarino, Luís, 2022, An annotated checklist of the vascular flora of Quiçama National Park, Angola, pp. 1-67 in Phytotaxa 557 (1) on page 44, DOI: 10.11646/phytotaxa.557.1.1, http://zenodo.org/record/6985699
Cultivation of PHB-producing cyanobacteria in wastewater on laboratory and pilot-scale
Creators: name: Mariotto, Marina
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Wastewater treatment
Liquid digestate
Aquaculture water
Bioplastic
Biopolymer
Nitrogen mass balance
579: Mikrobiologie

description: The cultivation of PHB-producing cyanobacteria is a promising process to optain the raw material for bio-based and biodegradable plastics. To commercialise photoautotrophic PHB production, the cultivation needs to be scaled up in open cultivation systems. Further, the use of wastewater as nutrient source improves the resource efficiency of the process, making it cheaper and more sustainable. Here, the feasibility of these steps was tested. First, the suitability of different PHB-producing cyanobacteria was compared in laboratory scale cultivations. Then, the species Synechococcus leopoliensis was cultivated in an open thin-layer photobioreactor (18 m2, 200 L), using a mineral medium, water from recirculating aquaculture systems and pre-processed liquid digestate as nutrient sources. Cultivations in all three media were successful. Cultivation in mineral medium resulted in both the highest final biomass yield (6 g L-1) and productivity (0.7 g L-1 d-1). Both wastewater-based media showed lower biomass yields and productivities (2 g L-1 and 0.25–0.3 g L-1 d-1). However, due to differences in the cultivation conditions (e.g. temperature, nutrient supply), final biomass yield and productivity do not represent the performance of the cultivations adequately. Therefore, relative parameters such as nitrogen and energy conversion ratios were applied. All cultivations in the open system were continued in the laboratory, where cultures were starved for 10 days under nutrient-depleted conditions (without nitrogen, phosphorus and both). This yielded comparatively low amounts of PHB (< 1 %dw). The comparison of the results suggest that PHB yields were influenced more by the initial cultivation condition than by the specific type of nutrient depletion. Thus, while the cultivation with waste streams in an open system is feasible, environmental parameters seem to influence PHB yields considerably and must be taken into account for the optimisation of the complete process.
Variations in the environmental footprint of cocoa value chains : the case of Swiss chocolate
Creators: name: Froborg, Francis
Publisher: name: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Year: 2022
Subjects: Cocoa
LCA
Variations
Variability
Uncertainty
Agriculture
333: Bodenwirtschaft und Ressourcen
630: Landwirtschaft

description: Life cycle assessment in general and that of cocoa specifically tends to lack completeness in examining the ecological impact as well as in examining uncertainties and variations. The study presented in this paper is a first step towards closing this gap. It focusses on agricultural practices of cocoa beans, taking into account 16 impact categories, and puts these results into the context of the value chain of cocoa liquor produced in Switzerland. Variations related to the different inputs are evaluated together with a comparison between countries, provinces, and cocoa varieties. It was found that cocoa cultivation is the driving factor of the ecological impact along the value chain for all impact categories. Large variations were found for all inputs to the extends that expected correlations between inputs like fertiliser usage on yield become blurred which hinders a proper analysis. Necessary steps forward are discussed.