cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Whole‐genome comparison between the type strain of Halobacterium salinarum (DSM 3754T) and the laboratory strains R1 and NRC‐1
Creators: name: Pfeiffer, Friedhelm
name: Losensky, Gerald
name: Marchfelder, Anita
name: Habermann, Bianca
name: Dyall‐Smith, Mike
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: genomic variability
subject: haloarchaea
subject: halobacteria
subject: megaplasmid
subject: type strain
subject: DDC 570 / Life sciences
subject: Comparative genomics
subject: Halobacterium
subject: Halobakterien

description: The genome of the Halobacterium salinarum type strain (91-R6, DSM 3754) was compared at the DNA and protein levels to the genomes of two well-studied laboratory strains, NRC-1 and R1. The chromosomes and portions of the plasmids were very closely related. However, distinct homologs for proteins involved in motility and N-glycosylation were encountered. Halobacterium salinarum is an extremely halophilic archaeon that is widely distributed in hypersaline environments and was originally isolated as a spoilage organism of salted fish and hides. The type strain 91-R6 (DSM 3754T) has seldom been studied and its genome sequence has only recently been determined by our group. The exact relationship between the type strain and two widely used model strains, NRC-1 and R1, has not been described before. The genome of Hbt. salinarum strain 91-R6 consists of a chromosome (2.17 Mb) and two large plasmids (148 and 102 kb, with 39,230 bp being duplicated). Cytosine residues are methylated (m4C) within CTAG motifs. The genomes of type and laboratory strains are closely related, their chromosomes sharing average nucleotide identity (ANIb) values of 98% and in silico DNA–DNA hybridization (DDH) values of 95%. The chromosomes are completely colinear, do not show genome rearrangement, and matching segments show <1% sequence difference. Among the strain-specific sequences are three large chromosomal replacement regions (>10 kb). The well-studied AT-rich island (61 kb) of the laboratory strains is replaced by a distinct AT-rich sequence (47 kb) in 91-R6. Another large replacement (91-R6: 78 kb, R1: 44 kb) codes for distinct homologs of proteins involved in motility and N-glycosylation. Most (107 kb) of plasmid pHSAL1 (91-R6) is very closely related to part of plasmid pHS3 (R1) and codes for essential genes (e.g. arginine-tRNA ligase and the pyrimidine biosynthesis enzyme aspartate carbamoyltransferase). Part of pHS3 (42.5 kb total) is closely related to the largest strain-specific sequence (164 kb) in the type strain chromosome. Genome sequencing unraveled the close relationship between the Hbt. salinarum type strain and two well-studied laboratory strains at the DNA and protein levels. Although an independent isolate, the type strain shows a remarkably low evolutionary difference to the laboratory strains.
Additional file 2 of Common predictors of cervical cancer related mortality in Ethiopia. A systematic review and meta-analysis
Creators: name: Hambisa, Hunduma Dina
name: Asfaha, Berhane Teklay
name: Ambisa, Biniam
name: Gudeta Beyisho, Abebech
Publisher: name: figshare
Year: 2024
Subjects: Biotechnology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 2
Transnationalism and faith communities: case studies of Serbian orthodox parishes in Australia and their links across the world
Creators: name: Peuraca, Zvjezdana
Publisher: name: RMIT University
Year: 2024

description: This study examined the current situation of the Serbian Orthodox Church both in its Australian and transnational contexts since the Serbian Orthodox Church functions as transnational network with churches linked globally. The research strategy was a combination of qualitative and quantitative methods. This included a case study approach which focused in four parishes in Australia, including interviews which involved forty six participants affiliated to Serbian Orthodoxy and four Serbian Orthodox priests who were individually interviewed. This research documented that the transnational links have been strengthened and facilitated by the revolution in information technology and travel. The bishop’s transnational travels and the frequent change of bishops in charge of the Australian diocese, the flow of religious personnel, the conduct of pilgrimages, the maintenance of links and contacts with priests and parishes in Serbia and around the world show the functioning of the Serbian Orthodox church as a transnational network. The research draws attention to a limited involvement of the Serbian Orthodox Church clergy in Australia with other faith leaders as well as limited participation in the interfaith network. As anticipated, the priests did not show much initiative in forming relationships with other religious communities. There are notable barriers in communicating with others such as language, the ethnocentric character of the church and unpreparedness of the clergy to work in a multicultural Australia. The future of the church as seen by participants and priests was assessed as mainly positive and Orthodoxy will continue to exist in Australia. The future of Orthodoxy is to be secured by attracting young people to the church and also by introducing English into the language of the liturgy.
Vulnerability to bushfires in south-eastern Australia: a case study from East Gippsland, Victoria
Creators: name: Whittaker, Joshua
Publisher: name: RMIT University
Year: 2024

description: This thesis is an analysis of human vulnerability to bushfires in the Wulgulmerang district of East Gippsland, Victoria, in south-eastern Australia. On January 30, 2003, bushfires devastated the small population of this isolated farming district. The fires destroyed homes, livelihood assets and public infrastructure. They also adversely affected the health, livelihoods and social lives of many local people. Australian bushfire research has traditionally focused on the geophysical dimensions of fire hazards and disasters, with little consideration of how cultural, economic, political and social factors shape people’s exposure to hazards and their capacities to cope and adapt to bushfire impacts. To date, there have been no systematic, social science analyses of human vulnerability to bushfires.

The vulnerability analysis presented in this thesis concentrates on two key research questions: (1) How and why were people exposed to hazards during the bushfires? and (2) How and why were people differentially capable of coping and adapting to the fires’ impacts? Qualitative methods were primarily used to investigate these questions, including semi-structured interviews with residents and landholders of the Wulgulmerang district, representatives of government departments and authorities, and others who participated in responses to the fires.

The thesis develops a multifaceted understanding of how and why people were vulnerable to the January 30 fires. Vulnerability is shown to arise from the circumstances of people’s day to day lives, which are shaped by factors both within and beyond their control. Local pressures and challenges – such as drought, declining farm incomes, depopulation, limited access to essential services, and political marginality – are shown to increase people’s exposure to bushfire hazards and reduce their capacities to cope and adapt. The thesis demonstrates the fundamental importance of sustainable livelihoods and regional economic and social vitality to the long-term goal of vulnerability reduction.
Minor elements distribution during the smelting of WEEE with copper scrap
Creators: name: Anindya, Alicia
Publisher: name: RMIT University
Year: 2024

description: The disposal of waste electrical and electronic equipment (WEEE) into landfill is no longer acceptable in most countries. WEEE contains toxic materials which cause environmental damage when they leach from landfill, but it also contains significant amounts of valuable metals and thus represents a potential resource for these metals. Reprocessing WEEE presents many technical challenges. The combination of metals found in WEEE is not the same as that found in ores, so the smelting techniques and slag systems that produce good recoveries of valuable metals from concentrates may not also produce high recoveries from WEEE. One attractive option for reprocessing WEEE is to add it to the feed to a secondary copper smelter using the traditional black copper route. Good examples of valuable minor elements in WEEE are tin and indium. The distribution behaviour of tin in common slags in copper smelting, calcium ferrite slag and ferrous silicate slag, is known but the behaviour of tin in ferrous calcium silicate slag is unknown. The way in which indium distributes in such a smelting circuit is also unknown because it is not a significant impurity in most copper ores. In this work the distribution of tin and indium between molten copper and slags whose compositions lie within the CaO-SiO2-FeOx (FCS) slag system has been reviewed. The results of experimental determinations of the tin and indium distribution at 1300oC have been reported and were used to calculate the activity coefficient of tin oxide and indium oxide in the slags. The activity coefficient data was utilised in a thermodynamic model of a secondary copper smelter to predict the way in which tin and indium deports to the various phases during the major processing stages.
title: Die akademische Diskussion der "Trostfrauen" in der VR China
Creators: name: Prouza, Michaela
Year: 2009

description: Diese Arbeit bietet einen Überblick zu den akademischen Debatten in der VRCh und verfolgt den Wandel der Themenschwerpunkte sowie der Kontextualisierung. Es wird argumentiert, dass – anders als in Japan oder Korea – Diskussionen nicht durch feministische Impulse stimuliert wurden und dass eine Erläuterung des Schicksals chinesischer Trostfrauen zögerlich erfolgte. Ein Steigen der Publikationszahlen wurde erst infolge der Erörterung der Trostfrauen im Kontext von Japans Kriegsverantwortung sowie Geschichtsrevisionismus ermöglicht. Infolge dieser Analyse wurden zwei Phänomene beobachtet. Erstens wird die Tatsache, dass chinesische Trostfrauen ein halbes Jahrhundert lang über ihre Vergangenheit schwiegen, angesprochen, nicht aber näher erörtert. Zweitens wählt die deutliche Mehrheit der AutorInnen für Forschung sowie Präsentation der Ergebnisse eine faktenpositivistische Herangehensweise. Diese Arbeit widmet sich folglich der Problematik des Warums. Um die Gründe für Jahrzehnte des Schweigens zu ermitteln, orientiert sich diese Arbeit an Ueno Chizukos Thesen der Paradigmen der „Schande des Opfers“ sowie der „Schande der Nation“, relativiert diese allerdings, indem für den Fall der VRCh ergänzende Faktoren, wie internationale Interessen der Regierungsspitze sowie eine mögliche Komplizenschaft gefeierter chinesischer kommunistischer Widerstandskämpfer angeführt werden. Bei der Frage nach den Gründen für eine primär faktenpositivistische Herangehensweise wird zunächst argumentiert, dass eine genauere Definition des Positivismusbegriffes erforderlich ist, die in der akademischen Diskussion berücksichtigt werden muss. Die Attraktivität faktenpositivistischer Analysen wird einerseits durch eine zeitweilige Unattraktivität alternativer Ansätze, wie marxistisch-leninistischer oder feministischer erklärt, andererseits hängt die Wahl der Forschungs- und Präsentationsmethode auch von der Bezugsgruppe ab, die über einen bedeutenden Zeitraum aus japanischen Geschichtsrevisionisten bestand, deren Argumentation auf eben einer faktenpositivistischen Ebene erfolgte.
New legionella control options by UV and violet LEDs for hospitals and care facilities
Creators: name: Hessling, Martin
name: Schmid, Julian
name: Hoenes, Katharina
name: Vatter, Petra
Publisher: name: Technische Hochschule Ulm
Year: 2018
Subjects: subject: Technik in Gesundheit und Medizin
subject: Infection Control
subject: Ultraviolet Radiation
subject: Violet Light
subject: DDC 610 / Medicine & health
subject: Legionella
subject: Infektionsrisiko
subject: Ultraviolett

description: Legionella infections caused by contaminated water are a widespread problem worldwide. Discharge lamps like mercury vapor lamps are widely known for the disinfection properties of their radiation, but they suffer technical disadvantages, like high voltages and toxic content, and are, therefore, not suitable for some infection control applications. New high intensity ultraviolet (UV) and violet LEDs offer new approaches for Legionella control, because these bacteria are significantly light sensitive compared to other pathogens. One of the most important infection pathways is the inhalation of Legionella containing aerosols during showering. This problem could be reduced by a single strong UV LED within the shower head, which irradiates the passing water for some milliseconds. This practice can be especially beneficial in hospitals and care facilities. UV light offers only a limited penetration depth, however, even in pure water. To disinfect larger water volumes, e.g., in water dispensers, visible violet LEDs are more appropriate. Unfortunately, up to now, neither approach has been given much attention by potential users.
Melodic drumming in contemporary popular music : an investigation into melodic drum-kit performance practices and repertoire
Creators: name: Jordan, Michael
Publisher: name: RMIT University
Year: 2024

description: This project is an investigation of melodic drum-kit practices in popular and contemporary music. The development of melodic drum-kit playing techniques has helped create a more inclusive role for drum-kit players within ensembles and has increased the potential for drum-kit players to present solo elements in performance. The project artefacts of my research are six compositions presented on CD. They demonstrate performance and compositional techniques that encourage a melodic approach to drum-kit performance.

My research involved several methodological approaches these included: a) professional practice-based research, b) music composition and transcription, c) interviews with significant musicians familiar with drum-kit melodic practices and d) elements of autoethnography.

I refer to particular drum-kit performance techniques and practices such as mirroring, thinking melodically, spatial relationships between drum-kit instruments and ensemble players, as well as, internalising melodic and harmonic ideas and being in the moment. I have shown in my compositional project that melodic elements in drum-kit performance and composition encourage a broader and more inclusive role for drummers in improvised performance. This is evident in the ensemble versions of compositions submitted as part of this study.
Influences on teachers' judgements of students' literacy development in a Victorian context
Creators: name: Fehring, Heather
Publisher: name: RMIT University
Year: 2024

description: The research presented in this thesis investigates the influences on teachers' judgements of students' literacy development in a Victorian (Australia) context. By establishing the study within the paradigm known as constructivism (Guba & Lincoln, 1994) using constructivist (naturalistic) inquiry and qualitative methods of data collection (Denzin & Lincoln, 1994), the study describes through constructive, interpretive analysis the influences on teachers' decision making processes. By utilising the strengths of ethnographic participation an non-participation observation (Goetz & LeCompte, 1984), purposefully selecting case study school sites and participating teachers (Patton, 1990), and using the teachers' voice the influences on teachers' judgements of students' literacy development have been investigated through inductive analysis.

The literature review examines the diversity in the conceptualisation of the concept literacy, describes three of the major views regarding the historical and current theoretical perspectives underpinning English language learning, and presents an analysis of current literacy learning continua. The review focuses the study on a significant gap in the information pertaining to influences on teachers' decision making processes. The research investigates the complexities of teachers' decision making processes in the formation of literacy judgements. The data collection involved three school sites in metropolitan Melbourne, Victoria, Australia. The three case studies centred on three main teachers. To facilitate the triangulation of information additional data sources were used: key informant interviews; curriculum and policy documents and classroom and student artefacts.

Seven spheres of influence emerged from the data in this study. These spheres are identified as internalised reflective knowledge, assessment strategy selection, external considerations, dissemination, peer power, standards and macro political context. Recommendations for enhancing educational practice flow from the thesis; they have most relevance to teachers and principals in the field, educational policy makers, and to tertiary educators involved in educational change. This study augments the research pertaining to literacy assessment and reporting practices and to understanding of influences on teachers' judgemental processes.
Additional file 3 of Common predictors of cervical cancer related mortality in Ethiopia. A systematic review and meta-analysis
Creators: name: Hambisa, Hunduma Dina
name: Asfaha, Berhane Teklay
name: Ambisa, Biniam
name: Gudeta Beyisho, Abebech
Publisher: name: figshare
Year: 2024
Subjects: Biotechnology
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Supplementary Material 3
Preparation of clay-dye pigment and its dispersion in polymers
Creators: name: Sivathasan, Jamuna
Publisher: name: RMIT University
Year: 2024

description: This thesis is concerned with an experimental study of clay intercalation by organic dye molecule which is crucial for the successful development of a stable clay-dye pigment with combined advantages of organic dye and inorganic clay. Clay-dye pigments were prepared by two different methods. Two different organic dyes were used with unmodified clay and modified clay to study the intercalation. Characteristics of clay-dye pigment have been investigated using X-Ray Diffraction, Thermo-gravimetric Analysis and Transmission Electron Microscopy.

In this thesis it is shown that the absorption of cationic dye by unmodified clay in aqueous medium mainly takes place in the interlayer clay surface. More likely the dye molecules with aromatic quaternary ammonium cation intercalate the clay layer and strongly interacts with the clay interlayer oxygen plane, where solvent dye (which is hydrophobic in nature) adsorption by unmodified clay mainly takes place on outer surface of the clay. Dye molecules are weakly interacted with outer surface oxygen plane by hydrogen bonding or Vander Waals forces. Modified clay enabled the solvent dye to intercalate inside the clay interlayer surface with the suitable non-aqueous medium (because of its expanded structure). The modified clay suspension in the selected non-aqueous medium shows only partial desorption of alkyl ammonium molecule from the clay layer with the presence of both cationic dye and solvent dye. Therefore the penetrated dye molecules must have weakly interacted with the interlayer oxygen plane as well as the remaining alkyl ammonium molecule present inside the clay layer. It is believed that the thermal and UV stability of organic dye can only be facilitated by a specific interaction (ƒà-interactions) between aromatic alkyl ammonium cation of organic dye molecule and the interlayer oxygen plane of clay minerals. This interaction possibly enables the high thermal energy or the energy of the UV radiation to transmit immediately into the clay layer. Therefore organic dye molecules are protected from high energy loading and hence thermal and UV stability are improved.
sj-docx-1-pit-10.1177_15269248221132255 - Supplemental material for Effect of Preoperative Sarcopenia, Malnutrition and Functional status on Postoperative Morbidity Following Liver Transplantation
Creators: name: Prakash, Kelika
name: Sam, Amal Francis
name: K, Nandakumar
name: Tandon, Neha
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110305 Emergency Medicine
subject: FOS: Clinical medicine
subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-docx-1-pit-10.1177_15269248221132255 for Effect of Preoperative Sarcopenia, Malnutrition and Functional status on Postoperative Morbidity Following Liver Transplantation by Kelika Prakash, Amal Francis Sam, Nandakumar K and Neha Tandon in Progress in Transplantation
Spike residue 403 affects binding of coronavirus spikes to human ACE2
Creators: name: Zech, Fabian
name: Schniertshauer, Daniel
name: Jung, Christoph
name: Herrmann, Alexandra
name: Cordsmeier, Arne
name: Xie, Qinya
name: Nchioua, Rayhane
name: Prelli Bozzo, Caterina
name: Volčič, Meta
name: Koepke, Lennart
name: Müller, Janis A.
name: Krüger, Jana
name: Heller, Sandra
name: Stenger, Steffen
name: Hoffmann, Markus
name: Pöhlmann, Stefan
name: Kleger, Alexander
name: Jacob, Timo
name: Conzelmann, Karl-Klaus
name: Ensser, Armin
name: Sparrer, Konstantin M.J.
name: Kirchhoff, Frank
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular biology
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Molecular biology
subject: Microbiology
subject: Coronaviridae
subject: Mikrobiologie
subject: Molekularbiologie
subject: Coronaviren

description: The bat sarbecovirus RaTG13 is a close relative of SARS-CoV-2, the cause of the COVID-19 pandemic. However, this bat virus was most likely unable to directly infect humans since its Spike (S) protein does not interact efficiently with the human ACE2 receptor. Here, we show that a single T403R mutation increases binding of RaTG13 S to human ACE2 and allows VSV pseudoparticle infection of human lung cells and intestinal organoids. Conversely, mutation of R403T in the SARS-CoV-2 S reduces pseudoparticle infection and viral replication. The T403R RaTG13 S is neutralized by sera from individuals vaccinated against COVID-19 indicating that vaccination might protect against future zoonoses. Our data suggest that a positively charged amino acid at position 403 in the S protein is critical for efficient utilization of human ACE2 by S proteins of bat coronaviruses. This finding could help to better predict the zoonotic potential of animal coronaviruses.
title: Lessons Learned from a Clinical Investigation: Data Processing Aspects of the DiaFu-Study
Creators: name: Krüger, Peter
name: Seidel, Doerthe
name: Bauer, Stefan
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Dokumentation
subject: 610 Medical sciences; Medicine

description: Introduction: A decision of the Federal Joint Committee Germany stated that negative pressure wound therapy (NPWT) is not accepted as a standard therapy with full reimbursement by health insurance companies in Germany. The German government stated that further research of high quality is necessary in[for full text, please go to the a.m. URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
No sacrifice in sunshine, Walter Liberty Vernon : architect 1846-1914
Creators: name: Boyd, Noni
Publisher: name: RMIT University
Year: 2024

description: This thesis traces the emergence of the Free Style, advocated by the designers of the Art and Crafts Movement, in the public architecture of New South Wales (NSW), Australia. From 1890, when the English-trained architect Walter Liberty Vernon was appointed Government Architect, the formality of neoclassical architecture, favoured by a succession of Colonial Architects, vanished in favour of less monumental designs that revived traditional building arts, often employing colonial Australian forms. I have traced the evolution of the architectural work of Vernon and the Government Architect’s Branch (GAB) of the NSW Public Works Department from the Queen Anne Revival through the Federation style to the Arts and Crafts Free Style. I have also traced Vernon’s early work, beginning with his initial training in London and his work in Sydney in the 1880s. Vernon’s design work shows him to have become an advocate of the utopian socialism promoted by the leading theorists of the Arts and Crafts Movement. A strong social consciousness can be seen in the buildings designed by the GAB under Vernon, with a focus on the design of well-lit, well-ventilated, simply furnished and unornamented public buildings.

It is not simply in the handcrafted detailing of the state’s public buildings that the ideals of the Arts and Crafts Movement are apparent. I also aim to show how the improvements to the overall planning of institutions and the changes in the architectural style of public buildings reflect the social conscience of the Movement, whilst creating a designed environment. Vernon’s application of the ideals of the Art and Crafts Movement stretched far beyond designing individual highly-crafted buildings, encompassing the emerging disciplines of town planning and the Garden City Movement. In NSW the Free Style became the style of institutional reform, employed not only in the design of hospitals and asylums, but also in the design of workers’ housing and educational facilities across the state, including in the widespread urban renewal and suburban improvement undertaken in Sydney post 1900. Vernon’s legacy to the state of NSW is a series of elegant public buildings that employ the traditional arts of building: schools, hospitals and asylums, post offices, courthouses, police stations and workers’ housing.
Reducing the drink driving road toll : a case study in integrating communication and social policy enforcement
Creators: name: Snitow, Samantha
Publisher: name: RMIT University
Year: 2024

description: This thesis presents a case study of the drink drive initiatives, including marketing communications, legislation and enforcement practices implemented in the state of Victoria (Australia) between 1989-2000. It has been argued that the 51% reduction in road toll was related to these initiatives. In order to explore the veracity of these claims, a holistic case study approach was adopted. In addition to an examination of the communications tactics and extant practices of enforcement agencies, the study involved interviews with two distinct groups: professionals in various fields pertaining to road safety, and members of the general Victorian driving community. The focus of this work was on the advertising and communications campaigns that were run by the Transport Accident Commission from 1989-2000; however the policy and enforcement initiatives were also examined in terms of the ir potential impact on the lowering of the road toll. Suggestions for the improvement of policy and communication strategies within a social marketing context are made.
Spatiotemporally controlled release of Rho-Inhibiting C3 toxin from a protein–DNA hybrid Hydrogel for targeted inhibition of osteoclast formation and activity
Creators: name: Gacanin, Jasmina
name: Kovtun, Anna
name: Fischer, Stephan
name: Schwager, Victoria
name: Quambusch, Johanna
name: Kuan, Seah Ling
name: Liu, Weina
name: Boldt, Felix
name: Li, Chuang
name: Yang, Zhongqiang
name: Liu, Dongsheng
name: Wu, Yuzhou
name: Weil, Tanja
name: Barth, Holger
name: Ignatius, Anita
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: Clostridial Rho-inhibiting C3 toxin
subject: Matrigel
subject: Recombinant human dnase
subject: Cells
subject: Growths
subject: Prophylactic vertebroplasty
subject: Drug delivery systems
subject: Bone resorption
subject: DDC 610 / Medicine & health
subject: Hydrogels
subject: Osteoblasts
subject: Osteoclasts
subject: Osteoporosis
subject: NAD-ADP-Ribosyltransferase
subject: Rekombinantes Protein
subject: Osteolyse
subject: Vertebroplastie

description: In osteoporosis, bone structure can be improved by the introduction of therapeutic molecules inhibiting bone resorption by osteoclasts. Here, biocompatible hydrogels represent an excellent option for the delivery of pharmacologically active molecules to the bone tissue because of their biodegradability, injectability, and manifold functionalization capacity. The present study reports the preparation of a multifunctional hybrid hydrogel from chemically modified human serum albumin and rationally designed DNA building blocks. The hybrid hydrogel combines advantageous characteristics, including rapid gelation through DNA hybridization under physiological conditions and a self-healing and injectable nature with the possibility of specific loading and spatiotemporally controlled release of active proteins, making it an advanced biomaterial for the local treatment of bone diseases, for example, osteoporosis. The hydrogels are loaded with a recombinant Rho-inhibiting C3 toxin, C2IN-C3lim-G205C. This toxin selectively targets osteoclasts and inhibits Rho-signaling and, thereby, actin-dependent processes in these cells. Application of C2IN-C3lim-G205C toxin-loaded hydrogels effectively reduces osteoclast formation and resorption activity in vitro, as demonstrated by tartrate-resistant acid phosphatase staining and the pit resorption assay. Simultaneously, osteoblast activity, viability, and proliferation are unaffected, thus making C2IN-C3lim-G205C toxin-loaded hybrid hydrogels an attractive pharmacological system for spatial and selective modulation of osteoclast functions to reduce bone resorption.
title: MedDRA Coding tool – Studiendaten effektiv kodieren
Creators: name: Bergmann, Eckhard
name: Hahmann, Maik
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Dokumentation
subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Kodierung von Studiendaten mit Hilfe des Systems MedDRA stellt eine Herausforderung an alle Beteiligten dar. So ist zum einen das System MedDRA sehr komplex, zum anderen müssen für Zwischen- oder Endauswertungen recht große Datenmengen in kurzer Zeit verarbeitet werden.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
sj-docx-1-aop-10.1177_10600280221130280 – Supplemental material for A Meta-Analysis on the Impact of Prenatal and Early Childhood Antimicrobial Use on Autism Spectrum Disorders
Creators: name: Li, Li-guo
name: Fu, Hong-guang
name: Zhao, Yong-hong
name: Zhao, Peng-ju
name: Meng, Qing-kai
name: Zheng, Rui-juan
name: Li, En-yao
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-aop-10.1177_10600280221130280 for A Meta-Analysis on the Impact of Prenatal and Early Childhood Antimicrobial Use on Autism Spectrum Disorders by Li-guo Li, Hong-guang Fu, Yong-hong Zhao, Peng-ju Zhao, Qing-kai Meng, Rui-juan Zheng and En-yao Li in Annals of Pharmacotherapy
Increased in vitro anti‐HIV activity of caffeinium‐functionalized polyoxometalates
Creators: name: Enderle, Ana G.
name: Bosso, Matteo
name: Groß, Rüdiger
name: Heiland, Magdalena
name: Bollini, Mariela
name: Culzoni, María J.
name: Kirchhoff, Frank
name: Münch, Jan
name: Streb, Carsten
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Self-Assembly
subject: Antiviral Activity
subject: DDC 610 / Medicine & health
subject: Polyoxometalates
subject: HIV-1
subject: Cations
subject: HIV
subject: Polyoxometallate
subject: Kation

description: Cerium‐tungstate polyoxoanions are combined with caffeinium cations to give a hybrid organic‐inorganic material with anti‐HIV activity. Biochemical assays highlight the low cytotoxicity of the compounds together with their promising antiviral activity. Initial mechanistic studies provide information on their mode of action. Polyoxometalates (POMs), molecular metal oxide anions, are inorganic clusters with promising antiviral activity. Herein we report increased anti‐HIV‐1 activity of a POM when electrostatically combined with organic counter‐cations. To this end, Keggin‐type cerium tungstate POMs have been combined with organic methyl‐caffeinium (Caf) cations, and their cytotoxicity, antiviral activity and mode of action have been studied. The novel compound, Caf4K[β2‐CeSiW11O39]×H2O, exhibits sub‐nanomolar antiviral activity and inhibits HIV‐1 infectivity by acting on an early step of the viral infection cycle. This work demonstrates that combination of POM anions and organic bioactive cations can be a powerful new strategy to increase antiviral activity of these inorganic compounds.
title: Klinische Arzneimittelforschung – Neuerungen und Herausforderungen
Creators: name: Chase, Dagmar
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Medizinische Dokumentation
subject: 610 Medical sciences; Medicine

description: Dieses Tutorium stellt die EU Verordnung 536/2014 im Überblick vor und fokussiert auf die Prozeduren, die die tägliche Arbeit der Anwender stark verändern werden. Dazu zählen die neuen Einreichungs- und Genehmigungsverfahren wobei das EU Portal eine zentrale Rolle spielen wird.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Supplemental material - Is it all the same? Types of innovation and their relationship with direct control, technical control and algorithmic management
Creators: name: Fana, Marta
name: Villani, Davide
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material for Is it all the same? Types of innovation and their relationship with direct control, technical control and algorithmic management by Marta Fana and Davide Villani in European Journal of Industrial Relations
Histological image processing for the assessment of tissue engineered cartilage
Creators: name: Och, Fabian
name: Wenzel, Ulla
name: Hasch, Katja
name: Goldberg-Bockhorn, Eva
name: Rotter, Nicole
name: Hessling, Martin
name: Munz, Michael
Publisher: name: Technische Hochschule Ulm
Year: 2018
Subjects: subject: Technik in Gesundheit und Medizin
subject: DDC 610 / Medicine & health
subject: Knorpel
subject: Bioreaktor
subject: Bildanalyse
subject: Scaffold (Tissue Engineering)

description: Article refers on the Histological image processing for the assessment of tissue engineered cartilage.
Additional file 1 of The economic burden of obesity in 4 south-eastern European countries associated with obesity-related co-morbidities
Creators: name: Athanasakis, Kostas
name: Bala, Cornelia
name: Kokkinos, Alexander
name: Simonyi, Gabor
name: Karoliová, Klaudia Hálová
name: Basse, Amaury
name: Bogdanovic, Miodrag
name: Kang, Malvin
name: Low, Kaywei
name: Gras, Adrien
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Science Policy

description: Supplementary Material 1
Alberta’s Fiscal Responses to Fluctuations in Non-Renewable Resource Revenue
Creators: name: Ferede, Ergete
Publisher: name: The School of Public Policy Publications
Year: 2018

description: We investigate how successive Alberta governments have responded to shocks in non-renewable resource revenue over the period 1970 to 2017. Our results show that Alberta governments have increased spending by 63 cents in the fiscal year following a one dollar increase in real per capita non-renewable resource revenues.  On the other hand, when non-renewable resource revenues have declined year over year, Alberta governments have not adjusted spending or other own source tax revenues. As a result of these asymmetric responses to fluctuations in resource revenues, the province’s stock of financial assets has declined and its net debt has increased by $10,834 per capita or in total $46 billion dollars. The policy implication of our results is that provincial governments should put increases in non-renewable resource revenues in a fiscal stabilization fund or Alberta Heritage Saving Trust Fund rather than spending two-thirds of any short-term increase in revenues.  This would result in a less volatile spending pattern and a sustainable fiscal policy with better services and lower tax rates.
description: The School of Public Policy Publications, Vol 11 (2018)
title: Planung und Auswertung von Non-Inferiority-Studien
Creators: name: Hoffmann, Verena
name: Adolf, Daniela
name: Weiß, Christel
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Biometrie
subject: 610 Medical sciences; Medicine

description: Planung und Auswertung von Non-Inferiority-Studien    Für viele Erkrankungen existieren bereits effektive Therapien. Alternativen zu diesen Standardtherapien sind häufig nicht überlegen was den Hauptzielparameter angeht, aber besser verträglich oder kostengünstiger. In solchen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Different response of bacteria, archaea and fungi to process parameters in nine full‐scale anaerobic digesters
Creators: name: Langer, Susanne G.
name: Gabris, Christina
name: Einfalt, Daniel
name: Wemheuer, Bernd
name: Kazda, Marian
name: Bengelsdorf, Frank R.
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Biogas production
subject: Digesters
subject: DDC 570 / Life sciences
subject: DDC 580 / Botanical sciences
subject: Digester gas
subject: Bacterial communities
subject: Autoclaves
subject: Biogasgewinnung

description: Biogas production is a biotechnological process realized by complex bacterial, archaeal and likely fungal communities. Their composition was assessed in nine full-scale biogas plants with distinctly differing feedstock input and process parameters. This study investigated the actually active microbial community members by using a comprehensive sequencing approach based on ribosomal 16S and 28S rRNA fragments. The prevailing taxonomical units of each respective community were subsequently linked to process parameters. Ribosomal rRNA of bacteria, archaea and fungi, respectively, showed different compositions with respect to process parameters and supplied feedstocks: (i) bacterial communities were affected by the key factors temperature and ammonium concentration; (ii) composition of archaea was mainly related to process temperature; and (iii) relative abundance of fungi was linked to feedstocks supplied to the digesters. Anaerobic digesters with a high methane yield showed remarkably similar bacterial communities regarding identified taxonomic families. Although archaeal communities differed strongly on genus level from each other, the respective digesters still showed high methane yields. Functional redundancy of the archaeal communities may explain this effect. 28S rRNA sequences of fungi in all nine full-scale anaerobic digesters were primarily classified as facultative anaerobic Ascomycota and Basidiomycota. Since the presence of ribosomal 28S rRNA indicates that fungi may be active in the biogas digesters, further research should be carried out to examine to which extent they are important players in anaerobic digestion processes.
title: Complete, transparent and unbiased reporting as a requisite in research in the health sciences
Creators: name: Sauerbrei, Willi
name: Sekula, Peggy
name: Ammenwerth, Elske
name: Blümle, Anette
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Biometrie
subject: 610 Medical sciences; Medicine

description: For many years the quality of research in the health sciences has been heavily criticized. It is argued that serious improvement would be possible if biomedical research were better chosen, designed, executed, analyzed, regulated, managed, disseminated, and reported. Serious improvements are far from[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Supplemental material - Bone marrow mesenchymal stem cells response on collagen/hyaluronan/chondroitin scaffold enriched with gentamicin -loaded gelatin microparticles for skin tissue engineering
Creators: name: He, Xiaoliang
name: Wang, Shuai
name: Yu, Xinran
name: Zhou, Xiaohui
Publisher: name: SAGE Journals
Year: 2023
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material for Bone marrow mesenchymal stem cells response on collagen/hyaluronan/chondroitin scaffold enriched with gentamicin -loaded gelatin microparticles for skin tissue engineering by Xiaoliang He, Shuai Wang, Xinran Yu and Xiaohui Zhou in Journal of Biomaterials Applications Journal
title: Sind Open Access-Publikationen für Verlage aufwändiger zu bearbeiten?
Creators: name: Kuballa, Stefanie
name: Mielke, Corinna
name: Schulze, Mareike
name: Haux, Reinhold
name: Henning, Peter
name: Schürg, Andrea
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Biometrie
subject: Epidemiologie
subject: Medizinische Informatik
subject: 610 Medical sciences; Medicine

description: Einleitung: Bei Publikationen findet ein Wandel vom Subskriptionsmodell zum Open Access (OA)-Modell statt [ref:1]. Dieser betrifft auch die Medizinische Informatik, Biometrie und Epidemiologie. Hierbei ergibt sich u.a. die Frage, welche Modifikationen am Publikations-Workflow für das [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
Preprocessing strategies for sparse infrared spectroscopy: a case study on cartilage diagnostics
Creators: name: Tafintseva, Valeria
name: Lintvedt, Tiril Aurora
name: Solheim, Johanne Heitmann
name: Zimmermann, Boris
name: Rehman, Hafeez Ur
name: Virtanen, Vesa
name: Shaikh, Rubina
name: Nippolainen, Ervin
name: Afara, Isaac
name: Saarakkala, Simo
name: Rieppo, Lassi
name: Krebs, Patrick
name: Fomina, Polina
name: Mizaikoff, Boris
name: Kohler, Achim
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: preprocessing
subject: sparse spectra
subject: multiplicative signal correction
subject: quantum cascade lasers
subject: DDC 570 / Life sciences
subject: DDC 620 / Engineering & allied operations
subject: Quantum chaos
subject: Quantenchaos

description: The aim of the study was to optimize preprocessing of sparse infrared spectral data. The sparse data were obtained by reducing broadband Fourier transform infrared attenuated total reflectance spectra of bovine and human cartilage, as well as of simulated spectral data, comprising several thousand spectral variables into datasets comprising only seven spectral variables. Different preprocessing approaches were compared, including simple baseline correction and normalization procedures, and model-based preprocessing, such as multiplicative signal correction (MSC). The optimal preprocessing was selected based on the quality of classification models established by partial least squares discriminant analysis for discriminating healthy and damaged cartilage samples. The best results for the sparse data were obtained by preprocessing using a baseline offset correction at 1800 cm−1, followed by peak normalization at 850 cm−1 and preprocessing by MSC.
Mapping desire: queer space in New Brunswick
Creators: name: Kaplan, Avery
Publisher: name: No Publisher Supplied
Year: 2024

description: Queer history has been ignored or hidden in spaces due to bias, discrimination, and even ignorance. To make hidden queer histories visible, this paper focuses on the local queer history of New Brunswick, New Jersey. This work collects, analyzes, and maps out queer spaces in New Brunswick and is guided by queer and post-structuralist thinking. Queer theory also provided inspiration for the aesthetics and representation used in the renderings. Additionally, the paper engages with the creation of small communities in the 1950s-1960s to try to understand how queer people were thought of by general heteronormative society. Then, this project moves through ephemera of the late 20th century that is available in the Rutgers University archives. To link the past to the present, modern stories from queer individuals who live in New Brunswick are presented through anonymous cognitive maps. The concluding series of queer walking tour maps of the city synthesizes queer stories from these three time periods and sources. The walking tour includes significant places to the queer community, representative of both positive and negative emotions and experiences. This map makes visible the hidden queer history of New Brunswick in an accessible format and allows people to understand the ways that queer expression has changed throughout time in New Brunswick.
Additional file 2 of The economic burden of obesity in 4 south-eastern European countries associated with obesity-related co-morbidities
Creators: name: Athanasakis, Kostas
name: Bala, Cornelia
name: Kokkinos, Alexander
name: Simonyi, Gabor
name: Karoliová, Klaudia Hálová
name: Basse, Amaury
name: Bogdanovic, Miodrag
name: Kang, Malvin
name: Low, Kaywei
name: Gras, Adrien
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Marine Biology
subject: Science Policy

description: Supplementary Material 2
title: Die Publikation von medizinischen Forschungsdaten als Form des Data Sharings – Publikationsprozess im Fachrepositorium Lebenswissenschaften
Creators: name: Lindstädt, Birte
Publisher: name: German Medical Science GMS Publishing House
Year: 2017
Subjects: subject: Epidemiologie
subject: Medizinische Dokumentation
subject: 610 Medical sciences; Medicine

description: Einleitung: Als Teil der Medical Data Science leistet eine Publikation von Forschungsdaten einen Beitrag zur Dissemination, Reproduzierbarkeit und Nachnutzbarkeit von Forschungsergebnissen.    Es besteht eine große Heterogenität hinsichtlich der Art und Weise, wie und auf welchen Wegen Forschungsdaten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 62. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)
title: Werbung im Italienischunterricht
Creators: name: Vollmann, Katharina
Year: 2009

description: Werbungen sind in der heutigen Gesellschaft ein allseits präsentes Phänomen, mit dem wir gelernt haben umzugehen. Je nachdem, wie sehr wir uns von ihnen beeinflussen lassen, ziehen wir unseren Nutzen aus ihnen. Werbung wird häufig als der Spiegel einer Gesellschaft beziehungsweise einer Alltagskultur bezeichnet. Lassen sich Werbungen daher auch im Unterricht einsetzen? Ist es mit Werbungen möglich Inhalte im Fremdsprachenunterricht besser zu „verkaufen“? Wie weit reicht das „Verkaufspotenzial“ von Werbungen im Italienischunterricht? Diese Diplomarbeit befasst sich mit den didaktischen Aufbereitungsmöglichkeiten von Werbungen im Italienischunterricht. Werbungen bieten aufgrund ihrer Heterogenität und ihrer zahlreichen Aspekte eine Vielzahl von Verwendungsmöglichkeiten beim Sprachenlernen. Im Vordergrund steht dabei die kontrastive Vorgehensweise, bei der eine italienischsprachige und deutschsprachige Werbung verglichen werden, um kulturelle Inhalte zu vermitteln. Ferner lassen sich sprachliche, medienwissenschaftliche und wirtschaftliche Komponenten im Unterricht anhand von Werbebeispielen erläutern.