cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hedotettix strictivertex Zheng 2006
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hedotettix
Hedotettix strictivertex

description: 62. Hedotettix strictivertex Zheng, 2006
Specimens examined. 4 ♂ 3♀, Fangcheng (Dongzhong), 21°38’N, 107°38’E, 400m alt, 12 Aug. 2012, collected by Min-Ping LIN.
Distribution. China (Guangxi, Yunnan).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 4: Figure S3. of Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling
Creators: name: Berwick, Daniel
name: Javaheri, Behzad
name: Wetzel, Andrea
name: Hopkinson, Mark
name: Nixon-Abell, Jonathon
name: Grannò, Simone
name: Pitsillides, Andrew
name: Harvey, Kirsten
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Developmental Biology
subject: 60506 Virology
subject: Computational Biology

description: Increased canonical Wnt activity in Lrrk2 knockout cells. A, B) Cells were transfected with TK-renilla and TOPflash or FOPflash in the presence of A) FLAG-DVl1 or C) GFP-FZD5 and HA-LRP6, or appropriate vector controls. A) 1-way ANOVA (n = 9; F = 146.199, p
title: Different p63 mediated response induced by doxorubicin and cisplatin: P63 activation by c-Abl in the cisplatin induced apoptotic pathway
title: p63 risponde diversamente a cisplatino e doxorubicina: attivazione di p63 da c-Abl nell'apoptosi indotta da cisplatino
titleType: AlternativeTitle
Creators: name: DI TELLA, LUCIA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: p63; c-Abl; apoptosis; cisplatin; doxorubicin; phosphorylation
subject: p63
subject: c-Abl
subject: apoptosis
subject: cisplatin
subject: doxorubicin
subject: phosphorylation

description: 20. ciclo
Hedotettix bivalvatu
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hedotettix
Hedotettix bivalvatu

description: 63. Hedotettix bivalvatu s Zheng & Jiang, 2002
Specimens examined. 5 ♂ 3♀, Shangsi (Pingfu), 21°53’N, 107°38’E, 400m alt, 24 Jul. 2012, collected by Xiao- Dong LI.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Clinical and economic impact of Ventricular Assist Device infections: a real-world claims analysis
Creators: name: Peleg, Anton Y.
name: Feller, Erika D.
name: Müller, Marcus
name: Schulte-Eistrup, Sebastian
name: McGiffin, David
name: Zimpfer, Daniel
name: Holbrook, Reece
name: Margetta, Jamie
name: Seshadri, Swathi
name: Mokadam, Nahush A.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: VAD therapy has revolutionized the treatment of end-stage heart failure, but infections remain an important complication. The objective of this study was to characterize the clinical and economic impacts of VAD-specific infections. A retrospective analysis of a United States claims database identified members 18 years with a claim for a VAD implant procedure, at least 6 months of pre-implant baseline data, and 12 months of follow-up between June 1, 2016 and December 31, 2019. Cumulative incidence of infection was calculated. Infection and non-infection cohorts were compared regarding mortality, healthcare utilization, and total cost. Regression models were used to identify risk factors associated with infections and mortality. A total of 2,259 patients with a VAD implant were included, with 369 experiencing infection (12-month cumulative incidence 16.1%). Patients with infection were 2.1 times more likely to die (p < 0.001, 95% CI [1.5-2.9]). The mean 12-month total cost per US patient was $354,339 for the non-infection cohort and $397,546 for the infection cohort, a difference of $43,207 (p < 0.0001). VAD infections were associated with higher mortality, more healthcare utilization, and higher total cost. Strategies to minimize VAD-specific infections could lead to improved clinical and economic outcomes.
Hedotettix latifemurus Zheng & Wei 2005
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hedotettix
Hedotettix latifemurus

description: 64. Hedotettix latifemurus Zheng & Wei, 2005
Specimens examined. 3 ♂ 7♀, Fangcheng (Dalu), 21°53’N, 108°02’E, 350m alt, 3 Aug. 2012, collected by Min- Ping LIN.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 3: of Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells
Creators: name: Barcus, Craig
name: OâLeary, Kathleen
name: Brockman, Jennifer
name: Rugowski, Debra
name: Yuming Liu
name: Garcia, Nancy
name: Menggang Yu
name: Keely, Patricia
name: Eliceiri, Kevin
name: Schuler, Linda
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Conditions for immunohistochemical and immunofluorescence antibodies. (PDF 256 kb)
Cost-effectiveness of nivolumab versus surveillance for the adjuvant treatment of patients with urothelial carcinoma who are at high risk of recurrence: a US payer perspective
Creators: name: Brodtkorb, Thor-Henrik
name: Knight, Christopher
name: Kamgar, Farzam
name: Teitsson, Siguroli
name: Kurt, Murat
name: Patel, Miraj Y.
name: Poretta, Tayla
name: Mamtani, Ronac
name: Palmer, Stephen
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: To evaluate the cost-effectiveness of adjuvant nivolumab compared with surveillance for the treatment of patients with high-risk muscle-invasive urothelial carcinoma (MIUC) after radical resection from a US healthcare payer perspective and to investigate the impact of alternative modeling approaches on the cost-effectiveness results. A four-state, semi-Markov model consisting of disease free, local recurrence, distant recurrence, and death health states was developed to investigate the cost-effectiveness of nivolumab compared with surveillance over a 30-year time horizon. The model used data from the randomized CheckMate 274 trial (NCT02632409) and published literature to inform transitions among health states, and inputs on cost, utility, adverse event, and disease management. Scenario analyses were conducted to investigate the impact of model structure and key assumptions on the results. One-way deterministic and probabilistic sensitivity analysis were conducted to investigate the robustness of the results. Total expected costs were higher with nivolumab ($162 268) compared with surveillance ($62 965). Nivolumab was associated with improved survival (1.53 life-years gained compared with surveillance) and an incremental gain of 0.94 quality-adjusted life-years (QALYs). Although total treatment costs were higher for nivolumab, cost offsets were observed because of delayed or avoided recurrences and deaths experienced with nivolumab compared with observation. The incremental cost-effectiveness and cost-utility ratios were $64 929/life-year and $105 660/QALY. At the time of analysis, CheckMate 274 had limited follow-up on disease-free survival and no overall survival data. The limited evidence necessitated assumptions on modeling survival after each type of recurrence. Nivolumab is estimated to be a life-extending and cost-effective option for adjuvant treatment of MIUC for patients who are at high risk of recurrence after undergoing radical resection in the United States. Using a threshold of $150,000/QALY, the cost-effectiveness conclusions remained consistent across the scenario and sensitivity analyses conducted.
title: Integration of protein interaction and protein localization data
title: Integrazione dei dati di interazione proteica e dati di localizzazione proteica
titleType: AlternativeTitle
Creators: name: CEOL, ARNAUD
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: protein interaction; domain; protein localization; MINT; Domino; CellMint; ortholog
subject: protein interaction
subject: domain
subject: protein localization
subject: MINT
subject: Domino
subject: CellMint
subject: ortholog

description: 20. ciclo
ENFOQUES DE APRENDIZAJE Y RENDIMIENTO ACADÉMICO EN ESTUDIANTES DE AGRONOMÍA: PERIODO MARZO 2105-FEBRERO 2017
Creators: name: Nicole Albarracin Alvear, Anggy
Publisher: name: unknown
Year: 2024

description: Los enfoques de aprendizaje, ya sean profundos o superficiales, influyen en cómo los estudiantes adquieren conocimientos. Este estudio analiza su impacto en el rendimiento académico de estudiantes de agronomía, destacando que, aunque hubo un cambio hacia el enfoque profundo en cohortes recientes, las calificaciones se mantuvieron en niveles mínimos para aprobar.
title: Progetto e realizzazione di un dispositivo multistrato a film di diamante CVD
title: Project and development of a multi-layer CVD diamond
titleType: AlternativeTitle
Creators: name: SCOCCIA, MARIALBA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: rivelatori di particelle alfa; dispositivo multistrato; diamanti CVD; cristallo singolo; catodoluminescenza
subject: rivelatori di particelle alfa
subject: dispositivo multistrato
subject: diamanti CVD
subject: cristallo singolo
subject: catodoluminescenza

description: 20. ciclo
description: Cap. 1, I microsistemi - Cenni sulla Fabbricazione dei Microsistemi - Chemical Vapor Deposition (CVD) - Elettrodeposizione - Epitassia - Ossidazione termica - Physical Vapor Deposition (PVD) - Casting - Litografia Tipologie di microsistemi - Dispositivi microfluidodinamici - Dispositivi inerziali - Dispositivi a radiofrequenza - Dispositivi microattuatori - Dispositivi ottici - Principali Caratteristiche ed Applicazioni - I rivelatori - Classificazione dei rivelatori . - Cap. 2, Diamante - Le Caratteristiche del Diamante - Struttura cristallina - Struttura a bande - DensitÃ dei portatori di carica - Modello della conduttivitÃ elettrica - ConduttivitÃ in presenza di trappole - Distanza media di deriva dei portatori - Il rivelatore - Eccitazione dei portatori di carica - Decadimento degli elettroni nel diamante - Cap. 3, Sintesi e caratterizzazione - Crescita del Diamante CVD - Camera di crescita - Diamante policristallino e a singolo cristallo - Drogaggio - Caratterizzazione del Diamante CVD. - Cap. 4, Dispositivo multistrato - Rivelatori a ionizzazione - Teorema di Ramo - Efficienza di rivelazione nel caso di particelle - Rivelatori allo stato solido - Il diamante come rivelatore - Rivelatori al Diamante CVD - Dispositivo Multistrato. - Cap. 4, Esperienza di laboratorio - Apparato di misura - Misure - Bibliografia
Tetrix subulata Linnaeus 1758
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix subulata

description: 65. Tetrix subulata (Linnaeus, 1758)
Specimens examined. 3 ♂ 4♀, Fangcheng (Dongzhong), 21°38’N, 107°38’E, 400m alt, 24 Aug. 2012, collected by Min-Ping LIN.
Distribution. China (Sichuan, Guangxi, Yunnan, Guangdong); whole Europe; Asian part of Turkey, Asian part of Russia, all Caucasian countries, Kazakstan, Mongolia, Korean peninsula; America.
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 3: of Dietary treatment of Crohnâ  s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
Creators: name: Svolos, Vaios
name: Gerasimidis, Konstantinos
name: Buchanan, Elaine
name: Curtis, Lee
name: Garrick, Vikki
name: Hay, Jacqueline
name: Laird, Susan
name: Munro, Joanna
name: Gaya, Daniel
name: Russell, Richard
name: Hansen, Richard
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Computational Biology

description: Survey on Dietary Treatment for Crohnâ  s Disease Adult/Carer Version. (PDF 241 kb)
Tetrix ceperoi subsp. ceperoi Bolivar 1887
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix ceperoi
Tetrix ceperoi ceperoi (bolívar, 1887)

description: 66. Tetrix ceperoi ceperoi (Bolívar, 1887)
Specimens examined. 4 ♂ 7♀, Shangsi (Jiaoan), 21°54’N, 107°53’E, 350m alt, 24 Aug. 2012, collected by Li- Liang LIN.
Distribution. whole China; North Africa; Europe; Japan.
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 1 of Nonlinear dimensionality reduction methods for synthetic biology biobricksâ   visualization
Creators: name: Jiaoyun Yang
name: Haipeng Wang
name: Huitong Ding
name: An, Ning
name: Alterovitz, Gil
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: This file contains more experiments on other types of biobricks. Besides, classification validation for the dimensionality reduction results are also included. These results are illustrated in two figures and two tables in the file. Figure S1: Dimensionality reduction results for various combinations of Plasmid backbones, Promoters, Terminators, Translational units, Protein generators, Primers by applying Isomap algorithm. Figure S2: Dimensionality reduction results for various combinations of Plasmid backbones, Promoters, Terminators, Translational units, Protein generators, Primers by applying Laplacian Eigenmaps algorithm. Table S1: Clustering accuracy comparison of dimensionality reduction results in Figures S1 and S2. Table S2: Classification accuracy comparison of dimensionality reduction results by Isomap and Laplacian Eigenmaps. (PDF 123 kb)
Additional file 1: of Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny
Creators: name: Furuse, Tamio
name: Miyake, Kunio
name: Kohda, Takashi
name: Kaneda, Hideki
name: Hirasawa, Takae
name: Yamada, Ikuko
name: Kushida, Tomoko
name: Misho Kashimura
name: Kobayashi, Kimio
name: Ishino, Fumitoshi
name: Kubota, Takeo
name: Shigeharu Wakana
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Values of the statistical analysis. (PDF 155 kb)
Realizzazione di un beamforming analogico per sistemi RFID
Creators: name: Cambriani, Piero
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: array factor; diodi varicap; RFID; beamforming
subject: dipolo; errore di fase; direttività;
subject: array factor
subject: diodi varicap
subject: RFID
subject: beamforming
subject: dipolo
subject: errore di fase
subject: direttività

description: 19. ciclo
Tetrix ceperoides Zheng & Jiang 1997
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix ceperoides

description: 67. Tetrix ceperoides Zheng & Jiang, 1997
Specimens examined. 3 ♂ 4♀, Fangcheng (Dongzhong), 21°38’N, 107°38’E, 400m alt, 15 Jul. 2013, collected by Min-Ping LIN.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Cost-effectiveness of TOMAC therapy for medication-refractory restless legs syndrome: an updated analysis based on Extension study data
Creators: name: Ryschon, Anne M.
name: Roy, Asim
name: Pietzsch, Jan B.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Patients with medication-refractory restless legs syndrome (RLS) have limited therapeutic options available for symptom relief. Tonic motor activation (TOMAC) presents a novel, non-invasive therapy for this patient population. The aim of this study was to conduct an updated cost-effectiveness analysis of TOMAC therapy based on recently available longer-term follow-up data. A previously published decision-analytic Markov model was utilized to project strategy-specific costs and outcomes over three-years and lifetime for TOMAC compared to status quo treatment (control). Cohort characteristics were based on 24-week clinical data from the extension cohort of the RESTFUL study, which included longer-term follow-up of RESTFUL completers who were assigned to continue or discontinue TOMAC use (TOMAC and control, respectively). The primary analysis outcome was the incremental cost-effectiveness ratio (ICER) in $ per quality-adjusted life year (QALY) gained, calculated using change in International RLS Study Group Rating Scale (IRLS) score as the effect measure. Extensive sensitivity analyses were performed. TOMAC treatment improved IRLS by 5.9 versus control, resulting in estimated utility improvement of +0.05. Over three-years and lifetime, TOMAC added 0.14 and 0.73 QALYs, at incremental costs of $6,751 and $27,440, resulting in projected ICERs of $47,609 and $37,823 per QALY gained, respectively. TOMAC was found to be cost-effective across all tested sensitivity analyses. The inclusion of longer follow-up data in the current analysis confirms earlier exploratory cost-effectiveness findings and suggest TOMAC therapy may provide a high-value treatment option for patients with medication-refractory RLS. Restless Legs Syndrome (RLS) is a is a neurological disorder, usually chronic, that causes an overwhelming urge to move one’s legs, with pronounced implications for patients’ quality of life. While pharmaceutical treatment options exist, a substantial proportion of patients are considered refractory to drug treatment. Tonic motor activation (TOMAC) therapy is a novel non-invasive neurostimulation approach that was recently cleared for market in the United States. This study sought to provide an updated economic analysis based on recently available data with longer follow-up. The findings of this study, based on data from the RESTFUL Extension study, suggest TOMAC therapy can be a high-value treatment alternative for refractory patients, providing meaningful quality of life improvement at costs that render it cost-effective in the United States. Future data with further extended follow-up will be useful to further broaden the evidence base underpinning these findings.
Identification of cellular kinases responsible for Hepatitis C Virus NS5A hyperphosphorylation
Creators: name: QUINTAVALLE, MANUELA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: Hepatitis C Virus; NS5A; hyperphosphorylation; cellular kinases
subject: Hepatitis C Virus
subject: NS5A
subject: hyperphosphorylation
subject: cellular kinases

description: 19. ciclo
Meccanismi molecolari e cellulari dell'ischemia sperimentale nello striato
Creators: name: Saulle, Emilia
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: synapses; neuronal plasticity; excitotoxicity; electrophysiology; striatum
subject: ischemia
subject: synapses
subject: neuronal plasticity
subject: excitotoxicity
subject: electrophysiology
subject: striatum
subject: ischemia

description: 19. ciclo
Cost-effectiveness of rimegepant oral lyophilisate compared to best supportive care for the acute treatment of migraine in the UK
Creators: name: Johnston, Karissa
name: Powell, Lauren C
name: Popoff, Evan
name: L’Italien, Gil J
name: Pawinski, Robert
name: Ahern, Aideen
name: Large, Sam
name: Tran, Thang
name: Jenkins, Aaron
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Pharmacology
Biological Sciences not elsewhere classified
Science Policy

description: Migraine is the most common disabling headache disorder and is characterized by recurrent throbbing head pain and symptoms of photophobia, phonophobia, nausea, and vomiting. Rimegepant 75mg, an oral lyophilisate calcitonin gene-related peptide antagonist, is the first treatment approved for both the acute and preventative treatment of migraine, and the first acute therapy approved in over 20-years. The objective was to assess the cost-utility of rimegepant compared with best supportive care (BSC) in the UK, for the acute treatment of migraine in the adults with inadequate symptom relief after taking at least 2 triptans, or for whom triptans are contraindicated or not tolerated. A de novo model was developed to estimate incremental costs and quality-adjusted life years (QALYs), structured as a decision tree followed by Markov model. Patients received rimegepant or BSC for a migraine attack and were assessed for response (pain relief at 2-hours). Responders and non-responders followed different pain trajectories over 48-hour cycles. Non-responders discontinued treatment while responders continued treatment for subsequent attacks, with a proportion discontinuing over time. Data sources included a post-hoc pooled analysis of the phase 3 acute rimegepant trials (NCT03235479, NCT03237845, NCT03461757), and a long-term safety study (NCT03266588). The analysis was conducted from the perspective of the UK National Health Service and Personal Social Services over a 20-year time horizon. Rimegepant resulted in an incremental cost-utility ratio (ICUR) of £10,309 per QALY gained vs BSC, which is cost-effectiveness at a willingness to pay threshold of £30,000/QALY. Rimegepant generated +0.44 incremental QALYs and higher incremental lifetime costs (£4,492). Improved QALYs for rimegepant were a result of less time spent with severe and moderate headache pain. This study highlights the economic value of rimegepant which was found to be cost-effective for the acute treatment of migraine in adults unsuitable for triptans.
Economic and healthcare resource utilization assessments of PET imaging in Coronary Artery Disease diagnosis: a systematic review and discussion of opportunities for future economic evaluations
Creators: name: Ferko, Nicole
name: Priest, Stacey
name: Almuallem, Lamees
name: Mooradally, Alicyia Walczyk
name: Wang, Di
name: Ramirez, Abril Oliva
name: Szabo, Erika
name: Cabra, Arturo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Cell Biology
Environmental Sciences not elsewhere classified
Science Policy

description: This systematic literature review (SLR) consolidated economic and healthcare resource utilization (HCRU) evidence for positron emission tomography (PET) and single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) to inform future economic evaluations. An electronic search was conducted in MEDLINE, Embase, and Cochrane databases from 2012–2022. Economic and HCRU studies in adults who underwent PET- or SPECT-MPI for coronary artery disease (CAD) diagnosis were eligible. A qualitative methodological assessment of existing economic evaluations, HCRU, and downstream cardiac outcomes was completed. Exploratory meta-analyses of clinical outcomes were performed. The search yielded 13,439 results, with 71 records included. Economic evaluations and comparative clinical trials were limited in number and outcome types (HCRU, downstream cardiac outcomes, and diagnostic performance) assessed. No studies included all outcome types and only one economic evaluation linked diagnostic performance to HCRU. The meta-analyses of comparative studies demonstrated significantly higher rates of early- and late-invasive coronary angiography and revascularization for PET- compared to SPECT-MPI; however, the rate of repeat testing was lower with PET-MPI. The rate of acute myocardial infarction was lower, albeit non-significant with PET- vs. SPECT-MPI. This SLR identified economic and HCRU evaluations following PET- and SPECT-MPI for CAD diagnosis and determined that existing studies do not capture all pertinent outcome parameters or link diagnostic performance to downstream HCRU and cardiac outcomes, thus, resulting in simplified assessments of CAD burden. A limitation of this work relates to heterogeneity in study designs, patient populations, and follow-up times of existing studies. Resultingly, it was challenging to pool data in meta-analyses. Overall, this work provides a foundation for the development of comprehensive economic models for PET- and SPECT-MPI in CAD diagnosis, which should link diagnostic outcomes to HCRU and downstream cardiac events to capture the full CAD scope.
Additional file 3: Table S3. of Race and BMI modify associations of calcium and vitamin D intake with prostate cancer
Creators: name: Batai, Ken
name: Murphy, Adam
name: Ruden, Maria
name: Newsome, Jennifer
name: Shah, Ebony
name: Dixon, Michael
name: Jacobs, Elizabeth
name: Hollowell, Courtney
name: Chiledum Ahaghotu
name: Kittles, Rick
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Association of Dietary Calcium and Vitamin D Intake with Prostate Cancer in Stratified Analysis Based on Body Mass Index. (PDF 279 kb)
title: Mobile robots based on multipole magnetoactive elastomer for controllable planar locomotion
Creators: name: Reiche, Marius
name: Zentner, Lena
name: Becker, Tatiana
Publisher: name: ŠafárikPress Publishing
Year: 2024
Subjects: subject: 620

description: The XIV. European Magnetic Sensors and Actuators Conference - EMSA 2024 : June 24-27, 2024, Košice, Slovakia : books of abstracts, p. 39
Additional file 1: of Dietary treatment of Crohnâ  s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey
Creators: name: Svolos, Vaios
name: Gerasimidis, Konstantinos
name: Buchanan, Elaine
name: Curtis, Lee
name: Garrick, Vikki
name: Hay, Jacqueline
name: Laird, Susan
name: Munro, Joanna
name: Gaya, Daniel
name: Russell, Richard
name: Hansen, Richard
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Computational Biology

description: Cover letter accompanying the questionnaire forms sent to families of paediatric Crohnâ  s disease patients. (PDF 214 kb)
Budget impact of dostarlimab plus carboplatin-paclitaxel for primary advanced or recurrent endometrial cancer from a third-party US payer perspective
Creators: name: Lubinga, Solomon J.
name: Walder, Lydia
name: Burton, Mark
name: Shen, Qin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Dostarlimab plus carboplatin-paclitaxel (CP) significantly increased progression-free survival in patients with primary advanced or recurrent endometrial cancer (pA/rEC) vs CP alone in the RUBY trial (NCT03981796). This analysis estimated the per-member-per-month (PMPM) costs of introducing dostarlimab + CP as a treatment alternative from a third-party US payer perspective. A budget impact model was developed to estimate the costs of introducing dostarlimab + CP into commercial and Medicare health plans over a 3-year time horizon (2023–2025). Costs were sourced from relevant literature and US-specific databases and were calculated using epidemiology data, clinical inputs, treatment costs, and market share estimates. Clinical inputs were sourced from primary clinical trials for each respective treatment (i.e. dostarlimab + CP, CP, pembrolizumab, pembrolizumab plus lenvatinib, bevacizumab + CP, and pembrolizumab + CP). Current and future market shares assumed dostarlimab + CP reduced the market share of CP only. Analyses were performed in mismatch repair–deficient/microsatellite instability–high (dMMR/MSI-H) and overall populations using a US 2023 cost year. For a commercial plan, the model estimated (dMMR/MSI-H and overall populations) that 7 and 26 patients would be treated with dostarlimab + CP, respectively; average annual budget impacts per patient treated were $118,257 and $116,094; average budget impacts per patient treated per month (PPPM) were $9,855 and $9,675; average budget impacts PMPM were $0.02 and $0.06. For a Medicare plan, the model estimated that 28 and 93 patients, respectively, would be treated with dostarlimab + CP. Average annual budget impacts per patient treated and PPPM were the same as those for the commercial plan in both populations; average budget impacts PMPM were $0.07 and $0.22, respectively. Introducing dostarlimab + CP as a first-line treatment for patients with pA/rEC results in minimal budget impact PMPM from a US third-party payer’s perspective. Together with the efficacy and safety results from RUBY, these results support the use of dostarlimab + CP as a treatment option. Dostarlimab with carboplatin–paclitaxel is a recently approved treatment for newly diagnosed advanced or recurrent endometrial cancer. This analysis was done to estimate the added costs that US commercial and Medicare health plans would have over 3 years if this treatment was covered. This analysis found that the budget increase for covering dostarlimab with carboplatin–paclitaxel was small ($0.02–$0.06 per commercial plan member per month; $0.07–$0.22 per Medicare plan member per month).
Additional file 1 of Nonlinear dimensionality reduction methods for synthetic biology biobricksâ   visualization
Creators: name: Jiaoyun Yang
name: Haipeng Wang
name: Huitong Ding
name: An, Ning
name: Alterovitz, Gil
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: This file contains more experiments on other types of biobricks. Besides, classification validation for the dimensionality reduction results are also included. These results are illustrated in two figures and two tables in the file. Figure S1: Dimensionality reduction results for various combinations of Plasmid backbones, Promoters, Terminators, Translational units, Protein generators, Primers by applying Isomap algorithm. Figure S2: Dimensionality reduction results for various combinations of Plasmid backbones, Promoters, Terminators, Translational units, Protein generators, Primers by applying Laplacian Eigenmaps algorithm. Table S1: Clustering accuracy comparison of dimensionality reduction results in Figures S1 and S2. Table S2: Classification accuracy comparison of dimensionality reduction results by Isomap and Laplacian Eigenmaps. (PDF 123 kb)
Conformationally constrained peptides as new nanomaterials for electrons and energy transfer
Creators: name: GATTO, EMANUELA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2008
Subjects: subject: peptides; foldamer; electron transfer; SAM; photocurrent; 310-helix
subject: peptides
subject: foldamer
subject: electron transfer
subject: SAM
subject: photocurrent
subject: 310-helix

description: 19. ciclo
Foslevodopa/foscarbidopa (LDp/CDp) in advanced Parkinson’s Disease (aPD): demonstration of savings from a societal perspective in the UK
Creators: name: Chaudhuri, K. Ray
name: Bergmann, Lars
name: Belsey, Jonathan
name: Boodhna, Trishal
name: Leoncini, Emanuele
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: In advanced Parkinson’s disease (aPD), adequate 24-hour control of OFF-time may not be achievable using oral/transdermal therapies. Clinical trials of foslevodopa/foscarbidopa (LDp/CDP) demonstrate meaningful reductions in OFF-time and OFF-related sleep disturbance in aPD. Previous analyses have only considered direct medical costs: this analysis considers a broader societal perspective (direct non-medical costs, informal care, loss of earnings, productivity, and tax). Inputs for the societal impact model were taken from a cost-utility model comparing LDp/CDp with best medical treatment (BMT), accepted by the UK National Institute of Health and Care Excellence (NICE). Quintiles of normalized OFF-time across a 16-hour waking day in each treatment group were applied to literature-based estimates for direct medical, non-medical, and indirect costs. The resulting state-specific cost estimates were applied to the modelled aPD patient population. The model estimates the potential UK population for LDp/CDp at 17,505. Continuous 24-hour delivery of LDp/CDp results in greater time spent in OFF-time states 0–1 (0–4 hours of OFF-time/16-hour waking day) vs BMT alone. Net savings if all eligible patients receive LDp/CDp are £79.1 M in year 1, £235.4 M in year 2, rising to £262.2 M in year 3, declining to £222.9 M in year 4 and £153.7 M in year 5 as disease progresses and the efficacy of LDp/CDp declines. The estimated total net savings are £953 M after 5 years. Results are robust in scenario analyses (excluding costs of excessive sleepiness, earnings loss, productivity, and tax loss). A NICE-accepted model was used as the economic modelling basis for the societal impact model, however, much of the data was derived from Adelphi datasets, with the potential for inconsistent definitions. When considered from a societal perspective, the use of LDp/CDp in aPD patients inadequately controlled on oral therapy is associated with net healthcare and societal annual savings of over £79.1 M vs BMT.
Tetrix tubercarina Zheng & Jiang 1994
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Tetrix
Tetrix tubercarina

description: 68. Tetrix tubercarina Zheng & Jiang, 1994
Specimens examined. 4 ♂ 6♀, Fangcheng (Nadong), 21°42’N, 107°40’E, 400m alt, 24 Aug. 2013, collected by Min-Ping LIN.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 172, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Giustizia di antico regime: il Tribunale criminale dell'Auditor Camerae (secc. XVI-XVII)
Creators: name: CICERCHIA, ANDREA
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: Auditor Camerae; tribunale; Chiesa; giurisdizione; Antico Regime; pontefice; giustizia; territorio; Stato della Chiesa
subject: Auditor Camerae
subject: tribunale
subject: Chiesa
subject: giurisdizione
subject: Antico Regime
subject: pontefice
subject: giustizia
subject: territorio
subject: Stato della Chiesa

description: 22. ciclo
Analysis of long-term clinical and cost impact of etranacogene dezaparvovec for the treatment of hemophilia B population in the United States
Creators: name: Yan, Songkai
name: McDade, Cheryl
name: Thiruvillakkat, Kris
name: Rouse, Robert
name: Sivamurthy, Krupa
name: Wilson, Michele
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Science Policy

description: Etranacogene dezaparvovec (EDZ), Hemgenix, is a gene therapy recently approved for people with hemophilia B (PwHB). To estimate long-term clinical impact and cost of EDZ in the United States (US). A decision-analytic model was developed to evaluate the long-term impact of introducing EDZ for PwHB over a 20-year time horizon. Factor IX (FIX) prophylaxis comparator was a weighted average of different FIX prophylaxis regimens based on US market share data. We compared a scenario in which EDZ is introduced in the US versus a scenario without EDZ. Clinical inputs (annualized FIX-treated bleed rate; adverse event rates) were obtained from HOPE-B phase 3 trial. EDZ durability input was sourced from an analysis predicting long-term FIX activity with EDZ. EDZ one-time price was assumed at $3.5 million. Other medical costs, including FIX prophylaxis, disease monitoring, bleed management, and adverse events were from literature. The model estimated annual and cumulative costs, treated bleeds, and joint procedures over 20 years from EDZ introduction. Approximately 596 PwHB were eligible for EDZ. EDZ uptake was estimated to avert 11,282 bleeds and 64 joint procedures over 20 years. Although adopting EDZ resulted in an annual excess cost over years 1-5 (mean: $53 million annually, total $265 million), annual cost savings were achieved beginning in year 6 (mean: $172 million annually; total $2.58 billion in years 6-20). The total cumulative 20-year cost savings was $2.32 billion, with cumulative cost savings beginning in year 8. Introducing EDZ to treat PwHB is expected to result in cost savings and patient benefit over 20 years. Initiating PwHB on EDZ sooner can produce greater and earlier savings and additional bleeds avoided. These results may be a conservative estimate of the full value of EDZ, as PwHB would continue to accrue savings beyond 20 years. This analysis assessed the long-term clinical and financial impact of introducing EDZ in the United States of America for people with severe or moderately severe hemophilia B. A decision-analytic model was developed comparing a scenario with EDZ and one without EDZ over 20 years. Introducing EDZ would avert 11,292 bleeds and 64 joint procedures over 20 years and would achieve cumulative cost savings in year 8, with a total cumulative 20-year cost saving of $2.32 billion.
Additional file 5: Table S5. of Race and BMI modify associations of calcium and vitamin D intake with prostate cancer
Creators: name: Batai, Ken
name: Murphy, Adam
name: Ruden, Maria
name: Newsome, Jennifer
name: Shah, Ebony
name: Dixon, Michael
name: Jacobs, Elizabeth
name: Hollowell, Courtney
name: Chiledum Ahaghotu
name: Kittles, Rick
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Institute of Medicine (IOM) Calcium and Vitamin D Dietary Reference Intakes and Prostate Cancer Stratified Based on Race. (PDF 262 kb)
Towards a theology of prayer in the thought of Søren Kierkegaard
Creators: name: Schuessler, Katherine A.
Publisher: name: The University of St Andrews
Year: 2022
Subjects: Prayer
Theology of prayer
Nineteenth century
Gospel of Matthew
Epistle of James
Eighteen Upbuilding Discourses
Christian spirituality
Paterology
Gift
Christian Discourses
Modern theology
Christian theology
Søren Kierkegaard

description: It has become increasingly accepted that, for Kierkegaard, theology and spirituality are practices that cannot be separated from one another. It has also been long acknowledged that Kierkegaard was a man of prayer, one who penned vivid prayers in both his journals and many of his published writings. Yet, little investigation has been done into how Kierkegaard’s theology shapes his understanding of prayer, nor how his understanding of prayer relates to his theology. This dissertation aims to address this lacuna by drawing together what Kierkegaard does say about prayer in a few of his published writings on James 1 and Matthew 6—writings which identify some of the chief theological underpinnings to prayer in Kierkegaard’s thinking. Beginning with his three James 1:17-22 upbuilding discourses published within ‘Eighteen Upbuilding Discourses’, Chapter 1 offers an analysis of Kierkegaard’s understanding of God the Father. Through James 1:17-22 Kierkegaard establishes a paterology that describes the Father as an unchanging Giver who always gives good and perfect gifts, the greatest of which is himself. Chapters 2 and 3 then look at two of Kierkegaard’s Matthew 6:24-34 discourses, which carry the bulk of Kierkegaard’s published comments on prayer. Chapter 2 looks at 1848’s ‘The Cares of the Pagans’, where Kierkegaard articulates that a Christian’s praying is the very thing that makes her a Christian. Chapter 3 then analyzes what Kierkegaard means by “to pray aright is to become silent” within 1849’s ‘The Lily in the Field and the Bird of the Air’. There prayer is something that begins in silence in order to listen to God, and is how an individual seeks first the kingdom of heaven. The last chapter, Chapter 4, brings the threads of the previous chapters together and provides the beginning of an account of Kierkegaard’s theology of prayer. To pray is to struggle with the heavenly Father’s unchanging love, yet on the basis of the Father’s gift of Jesus Christ and gift of the Spirit as one’s helper. For Kierkegaard, God is the giver and the receiver, and the reason and the motive, for all prayer.
title: L'antiriciclaggio e le indagini finanziarie
title: Money laundering and fiscal investigations
titleType: AlternativeTitle
Creators: name: CANNAROLI, SIMONE
Publisher: name: Università degli Studi di Roma "Tor Vergata"
Year: 2010
Subjects: subject: antiriciclaggio; contante; indagini fiscali; segnalazioni; sospette; professionisti
subject: antiriciclaggio
subject: contante
subject: indagini fiscali
subject: segnalazioni
subject: sospette
subject: professionisti

description: 22. ciclo
description: I. Il ruolo delle grandi organizzazioni amministrative II.Le difficoltà di applicazione di un metodo analitico aziendale alle realtà non organizzate III. La ricerca di una completa trama di informazioni documentali tracciabili e l’illusione del “grande fratello fiscale”. - CAPITOLO 1: il riciclaggio e la limitazione dell’uso del contante 1.1. Il riciclaggio 1.2. La limitazione all’uso del contante 1.3. Gli strumenti di pagamento 1.4. Gli assegni ed i libretti al portatore 1.5. I depositi a risparmio e l’imposta di bollo 1.6. Gli altri ambiti di intervento della limitazione alla circolazione del contante: money transfer, conti anonimi, operazioni frazionate 1.7. La comunicazione delle infrazioni relative alle limitazioni all’uso del contante e ai titoli al portatore. - CAPITOLO 2: la segnalazione delle operazioni sospette 2.1. I casi di Esenzione 2.2. Modalità di segnalazione 2.3. La riservatezza della segnalazione 2.4. Sviluppo delle segnalazioni 2.5. Ulteriori obblighi introdotti dal decreto legislativo n. 231 del 2007. - CAPITOLO 3: i soggetti obbligati: peculiarità e criticità 3.1. Intermediari finanziari e altri soggetti esercenti attività finanziaria. 3.1.1. Peculiarità operative 3.1.2. Inserimento dati statistici 3.1.3. La conoscenza effettiva della clientela. 3.2. I professionisti 3.2.1. Connessioni con accertamento fiscale 3.2.2. l ruolo dei professionisti. 3.2.3. Le modalità di segnalazione dei professionisti 3.2.4. La tutela della riservatezza 3.2.5. Flusso di ritorno 3.2.6. Formazione 3.2.7. Il ruolo degli organi di controllo e dei revisori contabili. 3.2.8. Gli Avvocati ed i Notai 3.3. Altri soggetti. - CAPITOLO 4: le indagini finanziarie 4.1. La banca dati sezionale (anagrafe dei conti) 4.2. Quando scatta l’attività di indagine finanziaria 4.3. La fase procedurale 4.4. I soggetti destinatari delle richieste da parte dell’Amministrazione finanziaria 4.5. Le notizie disponibili 4.6. La finalità dell’indagine finanziaria 4.7. Indagini nei confronti di terzi 4.8. Il trattamento dei costi occulti nell’accertamento 4.9. Spunti difensivi e tracciabilità dei ricavi o compensi. - CAPITOLO 5: l’antiriciclaggio a supporto del fisco 5.1. Evasione fiscale e riciclaggio 5.2. I reati tributari come reati presupposto 5.3. Le segnalazioni e l’evasione fiscale 5.4. I contesti di riferimento. - CAPITOLO 6: conclusioni 6.1. L’autoriciclaggio – una necessità non tributaria