cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
"PRETINHO BÁSICO": Uma análise de textos dos veículos Estadão, Folha de São Paulo, Elle e Vogue sobre o negro na marca LAB no SPFW
Creators: name: Jaine Araújo da Silva
Publisher: name: Zenodo
Year: 2019
Subjects: Empoderamento
Laboratório Fantasma
LAB
Moda
Negros
Racismo
Representação
São Paulo Fashion Week

description: Este trabalho discute a temática racial negra referente à realidade brasileira tendo como objeto de estudo 23 matérias jornalísticas sobre a grife LAB, pertencente aos cantores Emicida e Fióti. A pesquisa tem como objetivo compreender as representações construídas sobre o negro na marca, que em seus desfiles nas 42ª, 43ª e 44ª edições do São Paulo Fashion Week levou às passarelas noventa por cento de modelos negros. Para isso, é feita a análise do conteúdo de matérias dos sites Elle, Vogue, Estadão e Folha de São Paulo referentes aos desfiles da LAB em 2016 e 2017. Os textos foram divididos em duas temáticas: a participação da marca no evento e o episódio de racismo vivido por um dos donos logo após o último desfile. Ao fim da pesquisa, foi possível concluir que, embora os negros tenham sido exaltados em grande parte das matérias analisadas, o racismo, supostamente velado, continua existindo no Brasil. Os principais conceitos trabalhados são: raça, racismo, representação, empoderamento e lugar de fala. Como aporte teórico utilizam-se as ideias de Lilia Schwarcz, Silvio Almeida, Djamila Ribeiro, Joice Berth, Stuart Hall, Ruth Joffily, Laurence Bardin, entre outros.
"PRETINHO BÁSICO": Uma análise de textos dos veículos Estadão, Folha de São Paulo, Elle e Vogue sobre o negro na marca LAB no SPFW
Creators: name: Da Silva, Jaine Araújo
Publisher: name: Zenodo
Year: 2019
Subjects: Empoderamento; LAB; Moda; Negros; Racismo; Representação; São Paulo Fashion Week.

description: Este trabalho discute a temática racial negra referente à realidade brasileira tendo como objeto de estudo 23 matérias jornalísticas sobre a grife LAB, pertencente aos cantores Emicida e Fióti. A pesquisa tem como objetivo compreender as representações construídas sobre o negro na marca, que em seus desfiles nas 42ª, 43ª e 44ª edições do São Paulo Fashion Week levou às passarelas noventa por cento de modelos negros. Para isso, é feita a análise do conteúdo de matérias dos sites Elle, Vogue, Estadão e Folha de São Paulo referentes aos desfiles da LAB em 2016 e 2017. Os textos foram divididos em duas temáticas: a participação da marca no evento e o episódio de racismo vivido por um dos donos logo após o último desfile. Ao fim da pesquisa, foi possível concluir que, embora os negros tenham sido exaltados em grande parte das matérias analisadas, o racismo, supostamente velado, continua existindo no Brasil. Os principais conceitos trabalhados são: raça, racismo, representação, empoderamento e lugar de fala. Como aporte teórico utilizam-se as ideias de Lilia Schwarcz, Silvio Almeida, Djamila Ribeiro, Joice Berth, Stuart Hall, Ruth Joffily, Laurence Bardin, entre outros.
description: {"references": ["Jaine Ara\u00fajo da Silva. (2019). \"PRETINHO B\u00c1SICO\": Uma an\u00e1lise de textos dos ve\u00edculos Estad\u00e3o, Folha de S\u00e3o Paulo, Elle e Vogue sobre o negro na marca LAB no SPFW. Zenodo. https://doi.org/10.5281/zenodo.8350215"]}
Radiative ablation with two ionizing-fronts when opacity displays a sharp absorption edge
Creators: name: Poujade, Olivier
name: Bonnefille, Max
name: Vandenboomgaerde, Marc
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The interaction of a strong flux of photons with matter through an ionizing-front (I-front) is an ubiquitous phenomenon in the context of astrophysics and inertial confinement fusion (ICF) where intense sources of radiation put matter into motion. When the opacity of the irradiated material varies continuously in the radiation spectral domain, only one single I-front is formed. In contrast, as numerical simulations tend to show, when the opacity of the irradiated material presents a sharp edge in the radiation spectral domain, a second I-front (an edge-front) can form. A full description of the mechanism behind the formation of this edge-front is presented in this article. It allows to understand extra shocks (edge-shocks), displayed by ICF simulations, that might affect the robustness of the design of fusion capsules in actual experiments. Moreover, it may have consequences in various domains of astrophysics where ablative flows occur.
การศึกษาตลอดชีวิตเพื่อส่งเสริมความรอบรู้ด้านสุขภาพเกี่ยวกับบุหรี่ของเด็กและเยาวชน
Creators: name: ชนกนารถ บุญวัฒนะกุล
Publisher: name: มหาวิทยาลัยนอร์ทกรุงเทพ
Year: 2566
Subjects: การศึกษาตลอดชีวิต
ความรอบรู้ด้านสุขภาพ
บุหรี่
เด็กและเยาวชน

description: วารสารวิชาการ มหาวิทยาลัยนอร์ทกรุงเทพ, 12, 2, 1-11
NeuroBridge: a prototype platform for discovery of the long-tail neuroimaging data
Creators: name: Moore, Stephen M.
name: Sahoo, Satya S.
name: Wang, Yue
name: Wang, Lei
name: Kogan, Alex
name: Ambite, José Luis
name: Turner, Jessica A.
name: Dockes, Jerome
name: Lander, Howard
name: Poline, Jean-Baptiste
name: Appaji, Abhishek
name: Turner, Matthew D.
name: Herrick, Rick
name: Marcus, Daniel
name: Rajasekar, Arcot
name: Bijsterbosch, Janine
name: Wang, Xiaochen
Publisher: name: Frontiers Media SA
Year: 2023

description: Introduction Open science initiatives have enabled sharing of large amounts of already collected data. However, significant gaps remain regarding how to find appropriate data, including underutilized data that exist in the long tail of science. We demonstrate the NeuroBridge prototype and its ability to search PubMed Central full-text papers for information relevant to neuroimaging data collected from schizophrenia and addiction studies. Methods The NeuroBridge architecture contained the following components: (1) Extensible ontology for modeling study metadata: subject population, imaging techniques, and relevant behavioral, cognitive, or clinical data. Details are described in the companion paper in this special issue; (2) A natural-language based document processor that leveraged pre-trained deep-learning models on a small-sample document corpus to establish efficient representations for each article as a collection of machine-recognized ontological terms; (3) Integrated search using ontology-driven similarity to query PubMed Central and NeuroQuery, which provides fMRI activation maps along with PubMed source articles. Results The NeuroBridge prototype contains a corpus of 356 papers from 2018 to 2021 describing schizophrenia and addiction neuroimaging studies, of which 186 were annotated with the NeuroBridge ontology. The search portal on the NeuroBridge website https://neurobridges.org/ provides an interactive Query Builder, where the user builds queries by selecting NeuroBridge ontology terms to preserve the ontology tree structure. For each return entry, links to the PubMed abstract as well as to the PMC full-text article, if available, are presented. For each of the returned articles, we provide a list of clinical assessments described in the Section “Methods” of the article. Articles returned from NeuroQuery based on the same search are also presented. Conclusion The NeuroBridge prototype combines ontology-based search with natural-language text-mining approaches to demonstrate that papers relevant to a user’s research question can be identified. The NeuroBridge prototype takes a first step toward identifying potential neuroimaging data described in full-text papers. Toward the overall goal of discovering “enough data of the right kind,” ongoing work includes validating the document processor with a larger corpus, extending the ontology to include detailed imaging data, and extracting information regarding data availability from the returned publications and incorporating XNAT-based neuroimaging databases to enhance data accessibility.
Στάσεις και αντιλήψεις φιλίας νέων ενηλίκων με διαταραχή αυτιστικού φάσματος επιπέδου Ι υποστήριξης
Creators: name: Διαμαντοπούλου, Δέσποινα Γεωργίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2025
Subjects: Διαταραχή Αυτιστικού Φάσματος
Νέοι ενήλικες
Δημιουργία φιλιών
Autism Spectrum Disorder
Young adults
Forming friendships

description: Η παρούσα μελέτη, διερεύνησε τις στάσεις και τις αντιλήψεις φιλίας, 19 νέων ενηλίκων με Διαταραχή Αυτιστικού Φάσματος (ΔΑΦ) επιπέδου Ι υποστήριξης. Σκοπός της έρευνας ήταν η κατανόηση των παραγόντων που επηρέασαν το σχηματισμό και τη διατήρηση των φιλιών τους. Μέσα από ημιδομημένες συνεντεύξεις, επιχειρήθηκε η διερεύνηση των δυσκολιών που αντιμετώπισαν στις φιλικές τους σχέσεις, με στόχο την ενίσχυσή τους, για την αποτελεσματικότερη σύναψη φιλιών. Η ποιοτική ανάλυση των μετεγγραφών των συνεντεύξεων έγινε με τη μέθοδο των Miles και Huberman (1994). Τα αποτελέσματα της έρευνας, αποκάλυψαν δυσκολίες στην προσέγγιση φίλων και στην έναρξη των συνομιλιών μαζί τους. Κατέδειξαν ωστόσο, ότι όλοι οι συμμετέχοντες είχαν έναν τουλάχιστον φίλο και επιθυμούσαν να έχουν περισσότερους, με μεγαλύτερη διάρκεια συναναστροφής. Τα αποτελέσματα συζητούνται στα πλαίσια στοχευμένων παρεμβάσεων, για τη βελτίωση των κοινωνικών τους δεξιοτήτων και την καλλιέργεια ουσιαστικών φιλικών σχέσεων.
description: The current study investigated the attitudes and perceptions of friendship among 19 young adults with Autism Spectrum Disorder (ASD) level I support needs. The aim of the research was to understand the factors that influenced the formation and maintenance of their friendships. Through semi-structured interviews, the study investigated the challenges participants faced in their friendships, with the goal of strengthening these relationships for more effective friendship-building. The qualitative analysis of the interview transcripts was conducted using the Miles and Huberman (1994) method. The research findings revealed difficulties in approaching friends and starting conversations with them. However, they also showed that all participants had at least one friend and wished to have more, with longer durations of interaction. The results are discussed in the context of targeted interventions aimed at improving social skills and fostering meaningful friendships.
Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed
Creators: name: Mlynarczyk-Evans, Susanna
name: Kalantry, Sundeep
name: Alexander, Mary Kate
name: Royce-Tolland, Morgan
name: Magnuson, Terry
name: Panning, Barbara
name: Plocik, Alex
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Anumber of mammalian genes are expressed from only one of the two homologous chromosomes, selected at random in each cell. These include genes subject to X-inactivation, olfactory receptor (OR) genes, and several classes of immune system genes. The means by which monoallelic expression is established are only beginning to be understood. Using a cytological assay, we show that the two homologous alleles of autosomal random monoallelic loci differ from each other in embryonic stem (ES) cells, before establishment of monoallelic expression. The Polycomb Group gene Eed is required to establish this distinctive behavior. In addition, we found that when Eed mutant ES cells are differentiated, they fail to establish asynchronous replication timing at OR loci. These results suggest a common mechanism for random monoallelic expression on autosomes and the X chromosome, and implicate Eed in establishing differences between homologous OR loci before and after differentiation.
Canonical brackets of a toy model for the Hodge theory without its canonical conjugate momenta
Creators: name: Shukla, D.
name: Bhanja, T.
name: Malik, R. P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the toy model of a rigid rotor as an example of the Hodge theory within the framework of the Becchi-Rouet-Stora-Tyutin (BRST) formalism and show that the internal symmetries of this theory lead to the derivation of canonical brackets amongst the creation and annihilation operators of the dynamical variables where the definition of the canonical conjugate momenta is not required. We invoke only the spin-statistics theorem, normal ordering and basic concepts of continuous symmetries (and their generators) to derive the canonical brackets for the model of a one (0 + 1)-dimensional (1D) rigid rotor without using the definition of the canonical conjugate momenta anywhere. Our present method of derivation of the basic brackets is conjectured to be true for a class of theories that provide a set of tractable physical examples for the Hodge theory.
description: LaTeX file, 19 pages, journal version
Orlistat exerts anti-obesity and anti-tumorigenic effects in a transgenic mouse model of endometrial cancer
Creators: name: Wysham W.Z.
name: Roque D.R.
name: Fang Z.
name: Deng B.
name: Yin Y.
name: Bae-Jump V.
name: Zhou C.
name: Xu G.
name: Zhao Z.
name: Sun W.
name: Shen X.
Publisher: name: Frontiers Media SA
Year: 2023

description: Introduction: Among all cancers, endometrial cancer is most strongly associated with obesity, with more than 65% of endometrial cancers attributable to obesity and being overweight. Fatty acid synthase (FAS), a key lipogenic enzyme, is expressed in endometrial cancer tumors and is associated with a worse prognosis for this disease. Orlistat, an FAS inhibitor, is an FDA-approved weight loss medication that has demonstrated anti-tumor activity in a variety of preclinical cancer models. Methods: In this study, the Lkb1fl/flp53fl/fl mouse model of endometroid endometrial cancer was exposed to three diet interventions, including a high fat diet (obese), a low fat diet (lean) and switch from a high fat to a low fat diet, and then exposed to orlistat or placebo. Results: The mice fed a high-fat diet had significantly increased body weight and tumor weight compared to mice fed a low-fat diet. Switching from a high-fat diet to a low fat diet led to a reduction in mouse weight and suppressed tumor growth, as compared to both the high fat diet and low fat diet groups. Orlistat effectively decreased body weight in obese mice and inhibited tumor growth in obese, lean, and the high fat diet switch to low fat diet mouse groups through induction of apoptosis. Orlistat also showed anti-proliferative activity in nine of 11 primary cultures of human endometrial cancer. Discussion: Our findings provide strong evidence that dietary intervention and orlistat have anti-tumor activity in vivo and supports further investigation of orlistat in combination with dietary interventions for the prevention and treatment of endometrial cancer.
Conductivity and entanglement entropy of high dimensional holographic superconductors
Creators: name: Romero-Bermúdez, Aurelio
name: García-García, Antonio M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We investigate the dependence of the conductivity and the entanglement entropy on the space-time dimensionality $d$ in two holographic superconductors: one dual to a quantum critical point with spontaneous symmetry breaking, and the other modeled by a charged scalar that condenses at a sufficiently low temperature in the presence of a Maxwell field. In both cases the gravity background is asymptotically Anti de Sitter (AdS). In the large $d$ limit we obtain explicit analytical results for the conductivity at zero temperature and the entanglement entropy by a $1/d$ expansion. We show that the entanglement entropy is always smaller in the broken phase. As dimensionality increases, the entanglement entropy decreases, the coherence peak in the conductivity becomes narrower and the ratio between the energy gap and the critical temperature decreases. These results suggest that the condensate interactions become weaker in high spatial dimensions.
description: 38 pages, 7 figures
Microtubule binding by dynactin is required for microtubule organization but not cargo transport
Creators: name: Kim, Hwajin
name: Ling, Shuo-Chien
name: Kural, Comert
name: Rogers, Gregory C.
name: Rogers, Stephen L.
name: Gelfand, Vladimir I.
name: Selvin, Paul R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Dynactin links cytoplasmic dynein and other motors to cargo and is involved in organizing radial microtubule arrays. The largest subunit of dynactin, p150glued, binds the dynein intermediate chain and has an N-terminal microtubule-binding domain. To examine the role of microtubule binding by p150glued, we replaced the wild-type p150glued in Drosophila melanogaster S2 cells with mutant ΔN-p150 lacking residues 1–200, which is unable to bind microtubules. Cells treated with cytochalasin D were used for analysis of cargo movement along microtubules. Strikingly, although the movement of both membranous organelles and messenger ribonucleoprotein complexes by dynein and kinesin-1 requires dynactin, the substitution of full-length p150glued with ΔN-p150glued has no effect on the rate, processivity, or step size of transport. However, truncation of the microtubule-binding domain of p150glued has a dramatic effect on cell division, resulting in the generation of multipolar spindles and free microtubule-organizing centers. Thus, dynactin binding to microtubules is required for organizing spindle microtubule arrays but not cargo motility in vivo.
Positive feedback between Cdc42 activity and H + efflux by the Na-H exchanger NHE1 for polarity of migrating cells
Creators: name: Barber, Diane L.
name: Nalbant, Perihan
name: Frantz, Christian
name: Karydis, Anastasios
name: Hahn, Klaus M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: A fundamental feature of cell polarity in response to spatial cues is asymmetric amplification of molecules generated by positive feedback signaling. We report a positive feedback loop between the guanosine triphosphatase Cdc42, a central determinant in eukaryotic cell polarity, and H+ efflux by Na-H+ exchanger 1 (NHE1), which is necessary at the front of migrating cells for polarity and directional motility. In response to migratory cues, Cdc42 is not activated in fibroblasts expressing a mutant NHE1 that lacks H+ efflux, and wild-type NHE1 is not activated in fibroblasts expressing mutationally inactive Cdc42-N17. H+ efflux by NHE1 is not necessary for release of Cdc42–guanosine diphosphate (GDP) from Rho GDP dissociation inhibitor or for the membrane recruitment of Cdc42 but is required for GTP binding by Cdc42 catalyzed by a guanine nucleotide exchange factor (GEF). Data indicate that GEF binding to phosphotidylinositol 4,5–bisphosphate is pH dependent, suggesting a mechanism for how H+ efflux by NHE1 promotes Cdc42 activity to generate a positive feedback signal necessary for polarity in migrating cells.
Parent and Therapist Perceptions of the Feasibility, Acceptability, and Benefits of a Weekly Therapist-Led Massage Program for Extremely Preterm Infants in Neonatal Intensive Care
Creators: name: Soucie, Meredith
name: McCarty, Dana B.
name: Gilbert, Alana
name: O’Shea, T. Michael
name: Dusing, Stacey C.
name: LeBlond, Kristen D.
Publisher: name: MDPI
Year: 2023

description: Mothers of extremely preterm infants experience high rates of mental health disorders that impair maternal–infant interaction and lead to worse infant developmental outcomes. Therapist Education and Massage for Parent–Infant Outcomes (TEMPO) is a therapist-led program that standardizes the nature and frequency of parent education through weekly scheduled therapy sessions. Using a family-centered approach, the therapist facilitates positive maternal–infant interactions and massage interventions from birth throughout hospitalization with the goal of improving maternal mental health. This qualitative study presents the results of 19 parent interviews and of a focus group of four TEMPO interventionists to elicit feedback about the program. Overall, parents and therapists viewed the program positively. Parents and therapists valued the focus on parent education and engagement to increase parent competence and bonding opportunities. Both groups acknowledged that infant massage had both infant-centered and parent-centered benefits. One area where parent and therapist views did not align was regarding feasibility of TEMPO. Parents noted multiple logistical challenges to regular NICU visitation, but ultimately agreed that attending weekly therapy sessions was feasible. Therapists noted increased time and effort required of TEMPO and felt that institutional and system-level changes would be necessary to implement weekly parent education as standard of care.
Robust platform for engineering pure-quantum-state transitions in polariton condensates
Creators: name: Askitopoulos, A.
name: Liew, T. C. H.
name: Ohadi, H.
name: Hatzopoulos, Z.
name: Savvidis, P. G.
name: Lagoudakis, P. G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report on pure-quantum-state polariton condensates in optical annular traps. The study of the underlying mechanism reveals that the polariton wavefunction always coalesces in a single pure-quantum-state that, counter-intuitively, is always the uppermost confined state with the highest overlap to the exciton reservoir. The tunability of such states combined with the short polariton lifetime allows for ultrafast transitions between coherent mesoscopic wavefunctions of distinctly different symmetries rendering optically confined polariton condensates a promising platform for applications such as many-body quantum circuitry and continuous-variable quantum processing.
description: 5 pages, 5 figures
การจัดการเรียนรู้แบบบริการสังคม: การพัฒนานักศึกษาวิชาชีพครูมหาวิทยาลัยราชภัฏสู่การพัฒนาท้องถิ่นที่ยั่งยืน
Creators: name: สุธน วงค์แดง
Publisher: name: มหาวิทยาลัยนอร์ทกรุงเทพ
Year: 2566
Subjects: การจัดการเรียนรู้แบบบริการสังคม
นักศึกษาวิชาชีพครู
การพัฒนาท้องถิ่นที่ยั่งยืน

description: วารสารวิชาการ มหาวิทยาลัยนอร์ทกรุงเทพ, 12, 2, 12-27
On the canonical formalism of $f(R)$-type gravity using Lie derivatives
Creators: name: Ohkuwa, Yoshiaki
name: Ezawa, Yasuo
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We present a canonical formalism of the $f(R)$-type gravity using the Lie derivatives instead of the time derivatives by refining the formalism of our group. The previous formalism is a direct generalization of the Ostrogradski's formalism. However the use of the Lie derivatives was not sufficient in that Lie derivatives and time derivatives are used in a mixed way, so that the expressions are somewhat complicated. In this paper, we use the Lie derivatives and foliation structure of the spacetime thoroughly, which makes the procedure and the expressions far more concise.
description: 11 pages, no figures, Version accepted for publication in Eur. Phys. J. Plus
title: Chronische Herzinsuffizienz: Veränderungen im kardialen Intermediärstoffwechsel und Etablierung metabolischer Therapieansätze
Creators: name: Nguyen, Tien
Publisher: name: Friedrich-Schiller-Universität Jena
Year: 2020
Subjects: subject: Herzinsuffizienz
subject: Insulinresistenz
subject: Metabolismus
subject: 610

description: Eine Insulinresistenz geht oft mit mitochondrialen Defekten einher. Im Skelettmuskel kann eine mitochondriale Dysfunktion die Insulinempfindlichkeit beeinträchtigen. Interessanterweise scheint der umgekehrte Zusammenhang auch möglich zu sein. Kardiospezifischer Knockout des Insulinrezeptors kann mitochondriale und kontraktile Dysfunktion zur Folge haben. Wir zeigten bereits in einem durch Myokardinfarkt induzierten Herzinsuffizienzmodell, dass kardiale Insulinresistenz und verminderte mitochondriale Genexpression koexistieren. Es bleibt allerdings unklar, welche Veränderung zuerst auftritt und deshalb ursächlich eine Rolle spielen kann. Die vorliegende Arbeit überprüft den Zusammenhang zwischen kardialer Insulinresistenz und mitochondrialer Dysfunktion in einem weiteren etablierten Herzinsuffizienzmodell. Im Unterschied zur vorangegangenen Studie wurde hinsichtlich der obigen Fragestellung der Fokus auf die Chronologie der Veränderungen in der Entwicklung der Herzinsuffizienz gelegt.
Additional file 8 of Exploring the contribution of case study research to the evidence base for occupational therapy: a scoping review
Creators: name: McQuaid, Leona
name: Thomson, Katie
name: Bannigan, Katrina
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 8. Heat map contrasting interventions and practice contexts. Numbers and shading represent number of studies.
RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration
Creators: name: Boulter, Etienne
name: van Buul, Jaap D.
name: García-Mata, Rafael
name: Burridge, Keith
name: Allingham, Michael J.
name: Meller, Julia
name: Samson, Thomas
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: During trans-endothelial migration (TEM), leukocytes use adhesion receptors such as intercellular adhesion molecule-1 (ICAM1) to adhere to the endothelium. In response to this interaction, the endothelium throws up dynamic membrane protrusions, forming a cup that partially surrounds the adherent leukocyte. Little is known about the signaling pathways that regulate cup formation. In this study, we show that RhoG is activated downstream from ICAM1 engagement. This activation requires the intracellular domain of ICAM1. ICAM1 colocalizes with RhoG and binds to the RhoG-specific SH3-containing guanine-nucleotide exchange factor (SGEF). The SH3 domain of SGEF mediates this interaction. Depletion of endothelial RhoG by small interfering RNA does not affect leukocyte adhesion but decreases cup formation and inhibits leukocyte TEM. Silencing SGEF also results in a substantial reduction in RhoG activity, cup formation, and TEM. Together, these results identify a new signaling pathway involving RhoG and its exchange factor SGEF downstream from ICAM1 that is critical for leukocyte TEM.
A measure of physical reality
Creators: name: Bilobran, A. L. O.
name: Angelo, R. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: From the premise that an observable is real after it is measured, we envisage a tomography-based protocol that allows us to propose a quantifier for the degree of indefiniteness of an observable given a quantum state. Then, we find that the reality of an observable can be inferred locally only if this observable is not quantumly correlated with an informer. In other words, quantum discord precludes Einstein's notion of separable realities. Also, by monitoring changes in the local reality upon measurements on a remote system, we are led to define a measure of nonlocality. Proved upper bounded by discordlike correlations and requiring indefiniteness as a basic ingredient, our measure signals nonlocality even for separable states, thus revealing nonlocal aspects that are not captured by Bell inequality violations.
description: 6 pages, 2 figures, typos corrected, references added; accepted for publication in EPL
Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1
Creators: name: Wolfe, Breann L.
name: Marchese, Adriano
name: Trejo, JoAnn
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Protease-activated receptor-1 (PAR1), a G protein–coupled receptor (GPCR) for thrombin, is irreversibly activated by proteolysis. Consequently, PAR1 trafficking is critical for the fidelity of thrombin signaling. PAR1 displays constitutive and agonist-induced internalization, which are clathrin and dynamin dependent but are independent of arrestins. The clathrin adaptor AP2 (adaptor protein complex-2) is critical for constitutive but not for activated PAR1 internalization. In this study, we show that ubiquitination negatively regulates PAR1 constitutive internalization and specifies a distinct clathrin adaptor requirement for activated receptor internalization. PAR1 is basally ubiquitinated and deubiquitinated after activation. A PAR1 lysineless mutant signaled normally but was not ubiquitinated. Constitutive internalization of ubiquitin (Ub)-deficient PAR1 was markedly increased and inhibited by the fusion of Ub to the cytoplasmic tail. Ub-deficient PAR1 constitutive internalization was AP2 dependent like the wild-type receptor. However, unlike wild-type PAR1, AP2 was required for the internalization of activated Ub-deficient receptor, suggesting that the internalization of ubiquitinated PAR1 requires different endocytic machinery. These studies reveal a novel function for ubiquitination in the regulation of GPCR internalization.
Perenniporia fraxinea mitochondrial complete genome
Creators: name: Jeong, Jiran
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 310411
subject: Plant and fungus systematics and taxonomy

description: Perenniporia fraxinea is a semicircular mushroom with a diameter of 5-10 and a thickness of about 1cm, and has a pale yellow to pale yellow when the gat edge is first sterile, has a reddish-brown, dark-brown ring, and its flesh is corky.##Assembly-Data##Assembly Method :: NOVOPlasty v. 4.3.1Assembly Name :: Perenniporia fraxineaSequencing Technology :: Illumina
แนวทางการส่งเสริมช่องทางการตลาดที่สร้างสรรค์ของกลุ่มวิสาหกิจตำบลเกาะหลัก อำเภอเมือง จังหวัดประจวบคีรีขันธ์
Creators: name: กานต์ วัฒนะประทีป
Publisher: name: มหาวิทยาลัยนอร์ทกรุงเทพ
Year: 2566
Subjects: การส่งเสริม
ช่องทางการตลาด
วิสาหกิจชุมชน

description: วารสารวิชาการ มหาวิทยาลัยนอร์ทกรุงเทพ, 12, 2, 28-37
แนวทางการจัดการเพื่อเพิ่มประสิทธิภาพการดำเนินงานของธุรกิจซอฟต์แวร์ประยุกต์ในประเทศไทย
Creators: name: ฐิวากร ธัชหิรัญ
Publisher: name: มหาวิทยาลัยนอร์ทกรุงเทพ
Year: 2566
Subjects: การจัดการเชิงการจัดการ
ประสิทธิภาพการดำเนินงาน
ธุรกิจซอฟต์แวร์ประยุกต์

description: วารสารวิชาการ มหาวิทยาลัยนอร์ทกรุงเทพ, 12, 2, 38-47
Predominance of the Kitaev interaction in a three-dimensional honeycomb iridate: from ab-initio to spin model
Creators: name: Kim, Heung-Sik
name: Lee, Eric Kin-Ho
name: Kim, Yong Baek
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The recently discovered three-dimensional hyperhoneycomb iridate, $β$-Li$_2$IrO$_3$, has raised hopes for the realization of dominant Kitaev interaction between spin-orbit entangled local moments due to its near-ideal lattice structure. If true, this material may lie close to the sought-after quantum spin liquid phase in three dimensions. Utilizing ab-initio electronic structure calculations, we first show that the spin-orbit entangled basis, $j_{\rm eff}$=1/2, correctly captures the low energy electronic structure. The effective spin model derived in the strong coupling limit supplemented by the ab-initio results is shown to be dominated by the Kitaev interaction. We demonstrated that the possible range of parameters is consistent with a non-coplanar spiral magnetic order found in a recent experiment. All of these analyses suggest that $β$-Li$_2$IrO$_3$ may be the closest among known materials to the Kitaev spin liquid regime.
description: 9 pages, 6 figures, 2 tables
ปัจจัยสำคัญในการดำเนินธุรกิจของการเป็นผู้ประกอบการธุรกิจขนาดกลางและขนาดย่อม (SMEs) ในจังหวัดขอนแก่น
Creators: name: นิศราวรรณ ไพบูลย์พรพงศ์
Publisher: name: มหาวิทยาลัยนอร์ทกรุงเทพ
Year: 2566
Subjects: ปัจจัยในการดำเนินธุรกิจ
ธุรกิจขนาดกลางและขนาดย่อม (SMEs)
ผู้ประกอบการธุรกิจสถานบริการผู้สูงอายุ

description: วารสารวิชาการ มหาวิทยาลัยนอร์ทกรุงเทพ, 12, 2, 48-61
Spin waves in one-dimensional bi-component quasicrystals
Creators: name: Rychły, J.
name: Kłos, J. W.
name: Mruczkiewicz, M.
name: Krawczyk, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We studied finite Fibonacci sequence of Co and Py stripes aligned side-by-side and in direct contact with each other. Calculations based on continuous model including exchange and dipole interactions were performed for structures feasible for fabrication and characterization of main properties of magnonic quasicrystals. We have shown the fractal structure of the magnonic spectrum with a number of magnonics gaps of different width. Also localization of spin waves in quasicrystals and existence of surface spin waves in finite quaiscrystal structure is demonstrated.
description: 7 pages, 5 figures
Plasma phosphorylated tau181 as a biomarker of mild traumatic brain injury: findings from THINC and NCAA-DoD CARE Consortium prospective cohorts
Creators: name: Broglio, Steven P.
name: Giza, Christopher C.
name: Meier, Timothy B.
name: Devoto, Christina
name: Huber, Daniel
name: Cameron, Kenneth L.
name: Brooks, Alison
name: Pasquina, Paul
name: Jackson, Jonathan
name: Rowson, Steven
name: McAllister, Thomas
name: Lai, Chen
name: Duma, Stefan
name: Vorn, Rany
name: Gill, Jessica M.
name: CARE Consortium Investigators
name: Mithani, Sara
name: Turtzo, Christine
name: Latour, Lawrence
name: Guskiewicz, Kevin
name: Nelson, Lindsay D.
name: Harezlak, Jaroslaw
name: Mihalik, Jason P.
name: McGinty, Gerald
name: McCrea, Michael A.
Publisher: name: Frontiers Media SA
Year: 2023

description: Objective The aim of this study was to investigate phosphorylated tau (p-tau181) protein in plasma in a cohort of mild traumatic brain injury (mTBI) patients and a cohort of concussed athletes. Methods This pilot study comprised two independent cohorts. The first cohort—part of a Traumatic Head Injury Neuroimaging Classification (THINC) study—with a mean age of 46 years was composed of uninjured controls (UIC, n = 30) and mTBI patients (n = 288) recruited from the emergency department with clinical computed tomography (CT) and research magnetic resonance imaging (MRI) findings. The second cohort—with a mean age of 19 years—comprised 133 collegiate athletes with (n = 112) and without (n = 21) concussions. The participants enrolled in the second cohort were a part of a multicenter, prospective, case-control study conducted by the NCAA-DoD Concussion Assessment, Research and Education (CARE) Consortium at six CARE Advanced Research Core (ARC) sites between 2015 and 2019. Blood was collected within 48 h of injury for both cohorts. Plasma concentration (pg/ml) of p-tau181 was measured using the Single Molecule Array ultrasensitive assay. Results Concentrations of plasma p-tau181 in both cohorts were significantly elevated compared to controls within 48 h of injury, with the highest concentrations of p-tau181 within 18 h of injury, with an area under the curve (AUC) of 0.690–0.748, respectively, in distinguishing mTBI patients and concussed athletes from controls. Among the mTBI patients, the levels of plasma p-tau181 were significantly higher in patients with positive neuroimaging (either CT+/MRI+, n = 74 or CT−/MRI+, n = 89) compared to mTBI patients with negative neuroimaging (CT−/MRI−, n = 111) findings and UIC (P-values < 0.05). Conclusion These findings indicate that plasma p-tau181 concentrations likely relate to brain injury, with the highest levels in patients with neuroimaging evidence of injury. Future research is needed to replicate and validate this protein assay's performance as a possible early diagnostic biomarker for mTBI/concussions.
ERK5 promotes Src-induced podosome formation by limiting Rho activation
Creators: name: Martin, G. Steven
name: Kim, Tai Young
name: Ying, Olivia
name: Schramp, Mark
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Increased Src activity, often associated with tumorigenesis, leads to the formation of invasive adhesions termed podosomes. Podosome formation requires the function of Rho family guanosine triphosphatases and reorganization of the actin cytoskeleton. In addition, Src induces changes in gene expression required for transformation, in part by activating mitogen-activated protein kinase (MAPK) signaling pathways. We sought to determine whether MAPK signaling regulates podosome formation. Unlike extracellular signal–regulated kinase 1/2 (ERK1/2), ERK5 is constitutively activated in Src-transformed fibroblasts. ERK5-deficient cells expressing v-Src exhibited increased RhoA activation and signaling, which lead to cellular retraction and an inability to form podosomes or induce invasion. Addition of the Rho-kinase inhibitor Y27632 to ERK5-deficient cells expressing v-Src led to cellular extension and restored podosome formation. In Src-transformed cells, ERK5 induced the expression of a Rho GTPase-activating protein (RhoGAP), RhoGAP7/DLC-1, via activation of the transcription factor myocyte enhancing factor 2C, and RhoGAP7 expression restored podosome formation in ERK5-deficient cells. We conclude that ERK5 promotes Src-induced podosome formation by inducing RhoGAP7 and thereby limiting Rho activation.
A General Relativistic Null Hypothesis Test with Event Horizon Telescope Observations of the black-hole shadow in Sgr A*
Creators: name: Psaltis, Dimitrios
name: Ozel, Feryal
name: Chan, Chi-Kwan
name: Marrone, Daniel P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The half opening angle of a Kerr black-hole shadow is always equal to (5+-0.2)GM/Dc^2, where M is the mass of the black hole and D is its distance from the Earth. Therefore, measuring the size of a shadow and verifying whether it is within this 4% range constitutes a null hypothesis test of General Relativity. We show that the black hole in the center of the Milky Way, Sgr A*, is the optimal target for performing this test with upcoming observations using the Event Horizon Telescope. We use the results of optical/IR monitoring of stellar orbits to show that the mass-to-distance ratio for Sgr A* is already known to an accuracy of +-4%. We investigate our prior knowledge of the properties of the scattering screen between Sgr A and the Earth, the effects of which will need to be corrected for in order for the black-hole shadow to appear sharp against the background emission. Finally, we explore an edge detection scheme for interferometric data and a pattern matching algorithm based on the Hough/Radon transform and demonstrate that the shadow of the black hole at 1.3 mm can be localized, in principle, to within ~9%. All these results suggest that our prior knowledge of the properties of the black hole, of scattering broadening, and of the accretion flow can only limit this General Relativistic null hypothesis test with Event Horizon Telescope observations of Sgr A* to 10%.
description: To appear in the Astrophysical Journal
Theoretical investigation of the decay of the $N(2120)$ resonance to nucleon resonances near 1.7 GeV
Creators: name: Huang, Yin
name: He, Jun
name: Chen, Xu-Rong
name: Wang, Rong
name: Xie, Jun-Jun
name: Zhang, Hong-Fei
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Background: Until now the knowledge about nucleon resonances with a mass higher than 2 GeV has been scarce. Huge amounts of experimental data of the multipion photoproduction have been accumulated, and more can be expected in the future in facilities such as JLab 12 GeV. It makes it possible to investigate the decay of a nucleon resonance into another nucleon resonance. Purpose: The possibility to research the decay of the $N(2120)$ to nucleon resonances near 1.7 GeV in the three-pion photoproduction will be explored to provide useful information for future experimental study. Method: The pion and radiative decay amplitudes of nucleon resonances are studied within the constituent quark model, which is used to calculate the couplings constants, especially for the decay of a nucleon resonance near 2.1 GeV to another nucleon resonance near 1.7 GeV. The three-pion photoproduction off the neutron target, i.e.,$γn \toπ^{-}π^{-}Δ^{++}\to π^{-}π^{-}π^+ p$, is investigated based on the effective Lagrangian method with the coupling constant obtained form the decay amplitudes. Results: The resonance contribution with a state $N(^2P_M)\frac{3}{2}^{-}$ near 2.1 GeV decaying to a state $N(^4P_M)\frac{5}{2}^{-}$ near 1.7 GeV, i.\ e., $N(2120)\to N(1675)π$ is dominant in the process considered. The total cross section from the resonance contribution is at the order of 1 $μ$b and can be easily distinguished from the background. Conclusions: Our results suggest it is practicable to research the decay of the $N(2120)$ to the $N(1675)$ in experiment.
description: 5 pages, 5 figures
IPBES Invasive Alien Species Assessment, data management report for Chapter 3. Section 3.3.5.2: Unintended consequences of management through biological control
Creators: name: Vandvik, Vigdis
name: Pallewatta, P. K. T. Nirmalie S.
Publisher: name: Zenodo
Year: 2023
Subjects: Data management report

description: Section 3.3.5.2 assesses the role of unintended consequences of management (including biological control) as a driver of biological invasions. The experts conducted a systematic review to report on the existing knowledge on this driver. This systematic review consists in the main source of evidence for the section.
Localized Surface Plasmons in Vibrating Graphene Nanodisks
Creators: name: Wang, Weihua
name: Li, Bo-Hong
name: Stassen, Erik
name: Mortensen, N. Asger
name: Christensen, Johan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Localized surface plasmons are confined collective oscillations of electrons in metallic nanoparticles. When driven by light, the optical response is dictated by geometrical parameters and the dielectric environment and plasmons are therefore extremely important for sensing applications. Plasmons in graphene disks have the additional benefit to be highly tunable via electrical stimulation. Mechanical vibrations create structural deformations in ways where the excitation of localized surface plasmons can be strongly modulated. We show that the spectral shift in such a scenario is determined by a complex interplay between the symmetry and shape of the modal vibrations and the plasmonic mode pattern. Tuning confined modes of light in graphene via acoustic excitations, paves new avenues in shaping the sensitivity of plasmonic detectors, and in the enhancement of the interaction with optical emitters, such as molecules, for future nanophotonic devices.
ปัจจัยที่ส่งผลต่อการตัดสินใจใช้กระจกประหยัดพลังงานในอุตสาหกรรมวัสดุก่อสร้างที่เป็นมิตรกับสิ่งแวดล้อม
Creators: name: พีระสิทธิ์ คุณเลิศอาภรณ์
Publisher: name: มหาวิทยาลัยนอร์ทกรุงเทพ
Year: 2566
Subjects: กระจกประหยัดพลังงาน
ปัจจัยที่มีผลต่อการตัดสินใจซื้อกระจกประหยัดพลังงาน

description: วารสารวิชาการ มหาวิทยาลัยนอร์ทกรุงเทพ, 12, 2, 62-74
Plasmid-mediated virulence in Chlamydia
Creators: name: O'Connell, Catherine M.
name: Darville, Toni
name: Turman, Breanna J.
Publisher: name: Frontiers Media SA
Year: 2023

description: Chlamydia trachomatis infection of ocular conjunctiva can lead to blindness, while infection of the female genital tract can lead to chronic pelvic pain, ectopic pregnancy, and/or infertility. Conjunctival and fallopian tube inflammation and the resulting disease sequelae are attributed to immune responses induced by chlamydial infection at these mucosal sites. The conserved chlamydial plasmid has been implicated in enhancing infection, via improved host cell entry and exit, and accelerating innate inflammatory responses that lead to tissue damage. The chlamydial plasmid encodes eight open reading frames, three of which have been associated with virulence: a secreted protein, Pgp3, and putative transcriptional regulators, Pgp4 and Pgp5. Although Pgp3 is an important plasmid-encoded virulence factor, recent studies suggest that chlamydial plasmid-mediated virulence extends beyond the expression of Pgp3. In this review, we discuss studies of genital, ocular, and gastrointestinal infection with C. trachomatis or C. muridarum that shed light on the role of the plasmid in disease development, and the potential for tissue and species-specific differences in plasmid-mediated pathogenesis. We also review evidence that plasmid-associated inflammation can be independent of bacterial burden. The functions of each of the plasmid-encoded proteins and potential molecular mechanisms for their role(s) in chlamydial virulence are discussed. Although the understanding of plasmid-associated virulence has expanded within the last decade, many questions related to how and to what extent the plasmid influences chlamydial infectivity and inflammation remain unknown, particularly with respect to human infections. Elucidating the answers to these questions could improve our understanding of how chlamydia augment infection and inflammation to cause disease.
Detention times of microswimmers close to surfaces: Influence of hydrodynamic interactions and noise
Creators: name: Schaar, Konstantin
name: Zöttl, Andreas
name: Stark, Holger
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: After colliding with a surface, microswimmers reside there during the detention time. They accumulate and may form complex structures such as biofilms. We introduce a general framework to calculate the distribution of detention times using the method of first-passage times and study how rotational noise and hydrodynamic interactions influence the escape from a surface. We compare generic swimmer models to the simple active Brownian particle. While the respective detention times of source dipoles are smaller, the ones of pullers are larger by up to several orders of magnitude, and pushers show both trends. We apply our results to the more realistic squirmer model, for which we use lubrication theory, and validate them by simulations with multi-particle collision dynamics.
description: 6+6 pages, 4+5 figures
Presence of Perfluoroalkyl Substances in Landfill Adjacent Surface Waters in North Carolina
Creators: name: Walsh A.
name: Woods C.G.
Publisher: name: Multidisciplinary Digital Publishing Institute (MDPI)
Year: 2023

description: Landfills pose an important public health risk, especially in historically disenfranchised communities that are disproportionately sited for landfills and in rural areas where private wells may be impacted. Landfills are major sources of perfluoroalkyl substances (PFAS) that migrate into the surrounding environment. This study characterized PFAS in surface waters adjacent to two landfills, one in Sampson County (SC) and one in Orange County (OC) in North Carolina. In addition to municipal solid waste and construction and demolition waste, the landfill in SC accepts industrial sludge from a chemical plant that produces proprietary PFAS. Over four months, 35 surface water samples were collected at upstream, landfill-adjacent, and downstream/downgradient sites. Thirty-four PFAS were analyzed using liquid chromatography with tandem mass spectroscopy. Of those, six novel and six legacy PFAS were detected. Legacy PFAS were detected in surface water near both landfills, with the highest concentrations adjacent to the landfill. Novel PFAS were only detected in surface water near the SC landfill and showed the highest concentrations adjacent to the landfill, indicating offsite migration of PFAS. These findings support the need for more comprehensive and frequent monitoring of groundwater and surface water wells near landfills and stricter regulation regarding the landfilling of industrial materials.