cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation
Creators: name: Radicioni, Giorgia
name: Afshar, Roshi
name: Ling, Morris F.
name: Xavier, Ramnik
name: Moon, James J.
name: Hamilos, Daniel L.
name: Faustino, Lucas
name: Cho, Josalyn L.
name: Ford, Amina A.
name: Ng, Aylwin
name: Suter, Melissa J.
name: Han, Andre K.
name: Islam, Sabina A.
name: Harris, Robert S.
name: Kesimer, Mehmet
name: Luster, Andrew D.
name: Medoff, Benjamin D.
name: Kwok, William W.
name: Boucher, Richard
name: Griffith, Jason W.
name: Adams, David C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Despite systemic sensitization, not all allergic individuals develop asthma symptoms upon airborne allergen exposure. Determination of the factors that lead to the asthma phenotype in allergic individuals could guide treatment and identify novel therapeutic targets. In this study, we utilized segmental allergen challenge (SAC) of allergic asthmatics (AA) and allergic non-asthmatic controls (AC) to determine if there are differences in the airway immune response or airway structural cells that could drive the development of asthma. Both groups developed prominent allergic airway inflammation in response to allergen. However, asthmatic subjects had markedly higher levels of innate type 2 receptors on allergen-specific CD4+ T cells recruited into the airway. There were also increased levels of type 2 cytokines, increased total mucin and increased MUC5AC in response to allergen in the airways of AA subjects. Furthermore, type 2 cytokine levels correlated with the mucin response in AA but not AC subjects, suggesting differences in the airway epithelial response to inflammation. Finally, AA subjects had increased airway smooth muscle mass at baseline measured in vivo using novel orientation-registered optical coherence tomography (OR-OCT). Our data demonstrate that the development of allergic asthma is dependent on the responsiveness of allergen-specific CD4+ T cells to innate type 2 mediators as well as increased sensitivity of airway epithelial cells and smooth muscle to type 2 inflammation.
Searching for Ultralight Dark Matter Conversion in Solar Corona using Low Frequency Array Data
Creators: name: An, Haipeng
name: Chen, Xingyao
name: Ge, Shuailiang
name: Liu, Jia
name: Luo, Yan
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Ultralight dark photons and axions are well-motivated hypothetical dark matter candidates. Both dark photon dark matter and axion dark matter can resonantly convert into electromagnetic waves in the solar corona when their mass is equal to the solar plasma frequency. The resultant electromagnetic waves appear as monochromatic signals within the radio-frequency range with an energy equal to the dark matter mass, which can be detected via radio telescopes for solar observations. Here we show our search for converted monochromatic signals in the observational data collected by the high-sensitivity Low Frequency Array (LOFAR) telescope and establish an upper limit on the kinetic mixing coupling between dark photon dark matter and photon, which can reach values as low as $10^{-13}$ within the frequency range of $30-80$ MHz. This limit represents an improvement of approximately one order of magnitude better than the existing constraint from the cosmic microwave background observation. Additionally, we derive an upper limit on the axion-photon coupling within the same frequency range, which is better than the constraints from Light-Shining-through-a-Wall experiments while not exceeding the CERN Axion Solar Telescope (CAST) experiment or other astrophysical bounds.
description: 13 pages, 10 figures; v2: matched to journal version
Host gene expression classifiers diagnose acute respiratory illness etiology
Creators: name: Jaehne, Anja K.
name: Otero, Ronny M.
name: Burke, Thomas
name: Lucas, Joseph
name: Glickman, Seth W.
name: Hudson, Lori L.
name: Fowler, Vance G.
name: Freeman, Debra H.
name: Langley, Raymond J.
name: Mazur, Anna
name: Carin, Lawrence
name: Woods, Christopher W.
name: Zaas, Aimee K.
name: McClain, Micah T.
name: Nichols, Marshall
name: Tsalik, Ephraim L.
name: Ginsburg, Geoffrey S.
name: Cairns, Charles B.
name: Ko, Emily R.
name: Rivers, Emanuel P.
name: Henao, Ricardo
name: Quackenbush, Eugenia B.
name: Veldman, Tim
name: Kingsmore, Stephen F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Acute respiratory infections caused by bacterial or viral pathogens are among the most common reasons for seeking medical care. Despite improvements in pathogen-based diagnostics, most patients receive inappropriate antibiotics. Host response biomarkers offer an alternative diagnostic approach to direct antimicrobial use. This observational, cohort study determined whether host gene expression patterns discriminate non-infectious from infectious illness, and bacterial from viral causes of acute respiratory infection in the acute care setting. Peripheral whole blood gene expression from 273 subjects with community-onset acute respiratory infection (ARI) or non-infectious illness as well as 44 healthy controls was measured using microarrays. Sparse logistic regression was used to develop classifiers for bacterial ARI (71 probes), viral ARI (33 probes), or a non-infectious cause of illness (26 probes). Overall accuracy was 87% (238/273 concordant with clinical adjudication), which was more accurate than procalcitonin (78%, p<0.03) and three published classifiers of bacterial vs. viral infection (78-83%). The classifiers developed here externally validated in five publicly available datasets (AUC 0.90-0.99). A sixth publically available dataset included twenty-five patients with co-identification of bacterial and viral pathogens. Applying the ARI classifiers defined four distinct groups: a host response to bacterial ARI; viral ARI; co-infection; and neither a bacterial nor viral response. These findings create an opportunity to develop and utilize host gene expression classifiers as diagnostic platforms to combat inappropriate antibiotic use and emerging antibiotic resistance.
title: Eingetrübte Intraokularlinsen – Eine Analyse
Creators: name: Lindenberg, Ann-Sophie
name: Storsberg, J.
name: Liekfeld, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Seit einigen Jahren stellen Trübungen intraokularer Linsen (IOL) einen der häufigsten Gründe von IOL-Explantationen dar. Obwohl dies bei den Herstellern bekannt ist und einige Maßnahmen zur Behebung dieses Problems getroffen wurden, gehören IOL-Explantationen von[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
title: Biomaterial-Wechselwirkung während der Entfernung von Viskoelastika: Vergleichende Laborstudie einer neuen versus einer etablierten hydrophoben Acryl-Intraokularlinse
Creators: name: Fang, Hui
name: Schickhardt, S.
name: Wang, Q.
name: Munro, D. J.
name: Wolfe, P.
name: Jain, R.
name: Auffarth, G. U.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Zweck: Die Entfernungszeit von Viskoelastika (OVDs) aus Schweineaugen wurde zwischen den zu untersuchenden Intraokularlinsen (IOL), dem Modell Clareon CNA0T0 und dem Modell AcrySof SN60WF verglichen. Methode: Die natürliche Linse wurde mit Hilfe standardisierter Phakoemulsifikation von 20 frisch[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
title: Ultrastrukturelle Untersuchungen an hydrophoben Intraokularlinsen mittels Röntgen-Mikrocomputertomografie (µCT)
Creators: name: Brockmann, Tobias
name: Maenz, S.
name: Brockmann, C.
name: von Sonnleithner, C.
name: Bossert, J. B.
name: Bertelmann, E.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung: Analyse morphologischer Eigenschaften von hydrophoben Acryl-Intraokularlinse mittels Röntgen-Mikrocomputertomografie (µCT). Methodik: Sechs marktübliche +23,0 Dioptrien Intraokularlinsen (IOL) unterschiedlicher Hersteller (iStert 251 (Hoya), iSert 254 (Hoya), Tecnis[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
title: Bewertung des posterior-edge Profils von hydrophoben Intraokularlinsen mittels Rasterelektronenmikroskopie
Creators: name: Zhang, Lu
name: Łabuz, G.
name: Poompokawat, P.
name: Lieberwirth, I.
name: Merz, P.
name: Khoramnia, R.
name: Auffarth, G. U.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Zweck: Eine scharfe Optikkante wurde als wesentlicher Faktor zur Verhinderung der Entwicklung eines Nachstars (PCO) angesehen. In dieser Studie wollten wir die Abweichung eines perfekten Quadrats der Mikrokantenstruktur in verschiedenen hydrophoben Intraokularlinsen (IOLs) mithilfe der Rasterelektronenmikroskopie[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
Adiantum dawsonii Lellinger & J. Prado, Amer. Fern J.
Creators: name: Kessler, Michael
name: Smith, Alan R.
name: Prado, Jefferson
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Pteridaceae
Adiantum
Adiantum dawsonii

description: Adiantum dawsonii Lellinger & J.Prado, Amer. Fern J. 91(1): 6(–8), fig. 3. 2001.
 Range: — Bolivia (SC) and central Brazil.
 Ecology: —Rare (1 collection known), terrestrial on slopes and stream banks; 900 m.
 Notes: —Species of this group, including also A. cinnamomeum Lellinger & J.Prado and A. gracile Fée, both from Brazil, were treated by Lellinger & Prado (2001); these species are a small subset of the much larger A. tetraphyllum clade-2-pinnate species with copiously scaly rachises, numerous (per pinna) relatively small, short pinnules, and short-creeping rhizomes. Pinnules are relatively small, ca. 2 times longer than wide, with 35–55 pairs per pinna, yellow rounded glands present abaxially.
description: Published as part of Kessler, Michael, Smith, Alan R. & Prado, Jefferson, 2017, Prodromus of a fern flora for Bolivia. XXVII. Pteridaceae, pp. 201-250 in Phytotaxa 332 (3) on page 233, DOI: 10.11646/phytotaxa.332.3.1, http://zenodo.org/record/13723685
Unirationality of del Pezzo surfaces of degree two over finite fields
Creators: name: Festi, Dino
name: van Luijk, Ronald
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14J26, 14G15

description: We prove that every del Pezzo surface of degree two over a finite field is unirational, building on the work of Manin and an extension by Salgado, Testa, and Várilly-Alvarado, who had proved this for all but three surfaces. Over general fields of characteristic not equal to two, we state sufficient conditions for a del Pezzo surface of degree two to be unirational.
description: This is a short version (5 pages) of arXiv:1408.0269; the longer version contains more details and more general results
Local and transient gene expression primes the liver to resist cancer metastasis
Creators: name: Zhou, Yingqiu
name: Goodwin, Tyler J.
name: Musetti, Sara N.
name: Huang, Leaf
name: Liu, Rihe
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The liver is the primary site of metastasis for gastrointestinal cancers and is a location highly susceptible to the establishment of metastasis in numerous other primary cancers, including breast, lung, and pancreatic cancers. The current standard of care typically consists of primary tumor resection and systemic administration of potent but toxic chemotherapeutics, yielding a minimal improvement in the median survival rate. CXCL12, a chemokine, is a key factor for activating the migration/survival pathways of CXCR4+ cancer cells and for recruiting immunosuppressive cells to areas of inflammation. Therefore, reducing CXCL12 concentrations within the liver has the potential to decrease tumor and immunosuppressive cell activation/migration within the liver. However, because of off-target toxicities associated with systemic administration of anti-CXCL12 therapies, transient and liver-specific expression of a CXCL12 trap is necessary. To address this challenge, we developed a lipid calcium phosphate nanoparticle optimized for delivering plasmid DNA, encoding an engineered CXCL12 protein trap, to the nucleus of liver hepatocytes. This pCXCL12-trap formulation yielded transient (4 days) liver-specific expression, which greatly decreased the occurrence of liver metastasis in two aggressive liver metastasis models, including colorectal [CT-26(FL3)] and breast (4T1) cancers. Subsequent studies in an aggressive human colorectal liver metastasis model (HT-29) decreased the establishment of liver metastasis more effectively than did systemic administration of the CXCL12 protein trap and to a level comparable to a high-dose regimen of a potent CXCR4 antagonist (AMD3100).
Double parton distributions in the pion from lattice QCD
Creators: name: Bali, Gunnar S.
name: Castagnini, Luca
name: Diehl, Markus
name: Gaunt, Jonathan R.
name: Gläßle, Benjamin
name: Schäfer, Andreas
name: Zimmermann, Christian
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: 530 Physik

description: We perform a lattice study of double parton distributions in the pion, using the relationship between their Mellin moments and pion matrix elements of two local currents. A good statistical signal is obtained for almost all relevant Wick contractions. We investigate correlations in the spatial distribution of two partons in the pion, as well as correlations involving the parton polarisation. The patterns we observe depend significantly on the quark mass. We investigate the assumption that double parton distributions approximately factorise into a convolution of single parton distributions.
Counting irreducible binomials over finite fields
Creators: name: Heyman, Randell
name: Shparlinski, Igor E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11T06

description: We consider various counting questions for irreducible binomials over finite fields. We use various results from analytic number theory to investigate these questions.
description: 11 pages
Quantifying prion disease penetrance using large population control cohorts
Creators: name: Cohen, Yvonne
name: Mizusawa, Hidehiro
name: Sklar, Pamela
name: Sanjo, Nobuo
name: Calero, Miguel
name: Kraus, Theo F.J.
name: Hultman, Christina M.
name: Kitamoto, Tetsuyuki
name: De Pedro-Cuesta, Jesús
name: Uitterlinden, André G.
name: Kähler, Anna
name: Boyd, Alison
name: Collins, Steven J.
name: Zerr, Inga
name: Sathirapongsasuti, J. Fah
name: Bouaziz-Amar, Elodie
name: Kraaij, Robert
name: Minikel, Eric Vallabh
name: Boehnke, Michael
name: Poleggi, Anna
name: Rozemuller, Annemieke
name: O'Donnell-Luria, Anne H.
name: Laplanche, Jean-Louis
name: Samocha, Kaitlin E.
name: Blevins, Janis
name: Lek, Monkol
name: Brandel, Jean-Philippe
name: McCarroll, Steven
name: Hamaguchi, Tsuyoshi
name: Giese, Armin
name: Chen, Wei
name: MacArthur, Daniel G.
name: Haïk, Stéphane
name: Van Der Lee, Sven J.
name: Karczewski, Konrad J.
name: Will, Robert G.
name: Sullivan, Patrick F.
name: Jansen, Casper
name: Capellari, Sabina
name: Zhang, Shulin
name: Laakso, Markku
name: Ikram, M. Arfan
name: Van Rooij, Jeroen G. J.
name: McLean, Cory Y.
name: Mohlke, Karen L.
name: Estrada, Karol
name: Van Duijn, Cornelia M.
name: Nakamura, Yosikazu
name: Tung, Joyce Y.
name: Gambetti, Pierluigi
name: Hofman, Albert
name: Ponto, Claudia
name: Marshall, Jamie L.
name: Parchi, Piero
name: Vallabh, Sonia M.
name: Knight, Richard
name: Daly, Mark J.
name: Chambert, Kimberly
name: Yamada, Masahito
name: Yu, Linda P. C.
name: Purcell, Shaun M.
name: Ladogana, Anna
name: Eigenbrod, Sabina
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: More than 100,000 genetic variants are reported to cause Mendelian disease in humans, but the penetrance - the probability that a carrier of the purported disease-causing genotype will indeed develop the disease - is generally unknown. Here we assess the impact of variants in the prion protein gene (PRNP) on the risk of prion disease by analyzing 16,025 prion disease cases, 60,706 population control exomes, and 531,575 individuals genotyped by 23andMe, Inc. We show that missense variants in PRNP previously reported to be pathogenic are at least 30× more common in the population than expected based on genetic prion disease prevalence. While some of this excess can be attributed to benign variants falsely assigned as pathogenic, other variants have genuine effects on disease susceptibility but confer lifetime risks ranging from <0.1% to ~100%. We also show that truncating variants in PRNP have position-dependent effects, with true loss-of-function alleles found in healthy older individuals, supporting the safety of therapeutic suppression of prion protein expression.
Microscopic mechanism of thermomolecular orientation and polarization
Creators: name: Lee, Alpha A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Recent molecular dynamics simulations show that thermal gradients can induce electric fields in water that are comparable in magnitude to electric fields seen in ionic thin films and biomembranes. This surprising non-equilibrium phenomenon of thermomolecular orientation is also observed more generally in simulations of polar and non-polar size-asymmetric dumbbell fluids. However, a microscopic theory linking thermomolecular orientation and polarization to molecular properties is yet unknown. Here, we formulate an analytically solvable microscopic model of size-asymmetric dumbbell molecules in a temperature gradient using a mean-field, local equilibrium approach. Our theory reveals the relationship between the extent of thermomolecular orientation and polarization, and molecular volume, size anisotropy and dipole moment. Predictions of the theory agree quantitatively with molecular dynamics simulations. Crucially, our framework shows how thermomolecular orientation can be controlled and maximized by tuning microscopic molecular properties.
Role of Topology in Relaxation of One-Dimensional Stochastic Processes
Creators: name: Sawada, Taro
name: Sone, Kazuki
name: Hamazaki, Ryusuke
name: Ashida, Yuto
name: Sagawa, Takahiro
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Stochastic processes are commonly used models to describe dynamics of a wide variety of nonequilibrium phenomena ranging from electrical transport to biological motion. The transition matrix describing a stochastic process can be regarded as a non-Hermitian Hamiltonian. Unlike general non-Hermitian systems, the conservation of probability imposes additional constraints on the transition matrix, which can induce unique topological phenomena. Here, we reveal the role of topology in relaxation phenomena of classical stochastic processes. Specifically, we define a winding number that is related to topology of stochastic processes and show that it predicts the existence of a spectral gap that characterizes the relaxation time. Then, we numerically confirm that the winding number corresponds to the system-size dependence of the relaxation time and the characteristic transient behavior. One can experimentally realize such topological phenomena in magnetotactic bacteria and cell adhesions.
description: 6+17 pages, 4+15 figures
Luigi Ridolfi a Ubaldino Peruzzi (20 maggio 1876)
Creators: name: Ridolfi, Luigi
name: Peruzzi, Ubaldino
Publisher: name: Zenodo
Year: 2023
Subjects: Accademia dei Georgofili
Ridolfi, Luigi
Peruzzi, Ubaldino
Lettera
Letter
Carteggio
Correspondence
1876

description: Lettera di Luigi Ridolfi a Ubaldino Peruzzi Segnatura dell’unità documentale: Archivio storico dell’Accademia dei Georgofili, Carteggio amministrativo, Busta 47, 885. Natura: manoscritto. Consistenza: c. 1
description: Digitalizzato come parte della Mostra virtuale: Ubaldino Peruzzi : un percorso in rete : in occasione del bicentenario della nascita https://www.georgofili.it/contenuti/ubaldino-peruzzi-un-percorso-in-rete/17485
Quantum point contacts as heat engines
Creators: name: Pilgram, Sebastian
name: Sanchez, David
name: Lopez, Rosa
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The efficiency of macroscopic heat engines is restricted by the second law of thermodynamics. They can reach at most the efficiency of a Carnot engine. In contrast, heat currents in mesoscopic heat engines show fluctuations. Thus, there is a small probability that a mesoscopic heat engine exceeds Carnot's maximum value during a short measurement time. We illustrate this effect using a quantum point contact as a heat engine. When a temperature difference is applied to a quantum point contact, the system may be utilized as a source of electrical power under steady state conditions. We first discuss the optimal working point of such a heat engine that maximizes the generated electrical power and subsequently calculate the statistics for deviations of the efficiency from its most likely value. We find that deviations surpassing the Carnot limit are possible, but unlikely.
description: 9 pages, 2 figures. Contribution to the Physica E special issue on "Frontiers in quantum electronic transport" in memory of Markus Buttiker. Published version
A trust approach for sharing research reagents
Creators: name: Andrusiak, Kerry
name: Cynader, Zarya
name: Chawaf, Arij Al
name: Edwards, Aled
name: Moeser, Andrew
name: ElDessouki, Ahmed
name: Lee, Yunjeong
name: Zuercher, William J.
name: Charney, Rachel
name: Stern, Simon
name: Morgan, Max
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: The core feature of trusts-holding property for the benefit of others-is well suited to constructing a research community that treats reagents as public goods.
Dark Radiation from Neutrino Mixing after Big Bang Nucleosynthesis
Creators: name: Aloni, Daniel
name: Joseph, Melissa
name: Schmaltz, Martin
name: Weiner, Neal
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A light ($m_{νd} \lesssim $ MeV) dark fermion mixing with the Standard Model neutrinos can naturally equilibrate with the neutrinos via oscillations and scattering. In the presence of dark sector interactions, production of dark fermions is generically suppressed above BBN, but then enhanced at later times. Over much of the parameter space, we find that the dark sector equilibrates, even for mixing angles $θ_0$ as small as $10^{-13}$, and equilibration occurs at $T_{\rm equil} \simeq m_{νd} \left(θ_0^2 M_{Pl}/ m_{νd} \right)^{1/5} $ which is naturally at most a few orders of magnitude above the dark fermion mass. The implications of this are twofold: one, that light states are often only constrained by the CMB and LSS without leaving an imprint on BBN, and two, that sectors which equilibrate before recombination will typically have a mass threshold before recombination, as well. This can result in dark radiation abruptly transitioning from non-interacting to interacting, or vice-versa, a ''step'' in the amount of dark radiation, and dark matter with similar transitions in its interactions, all of which can leave important signals in the CMB and LSS, and may be relevant for cosmological tensions in observables such as $H_0$ or $S_8$. Minimal models leave an unambiguous imprint on the CMB above the sensitivity of upcoming experiments.
description: 6 pages, 2 figures
Strong Orientational Coordinates and Orientational Order Parameters For Symmetric Objects
Creators: name: Haji-Akbari, Amir
name: Glotzer, Sharon C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Recent advancements in the synthesis of anisotropic macromolecules and nanoparticles have spurred an immense interest in theoretical and computational studies of self-assembly. The cornerstone of such studies is the role of shape in self-assembly and in inducing complex order. The problem of identifying different types of order that can emerge in such systems can, however, be challenging. Here, we revisit the problem of quantifying orientational order in systems of building blocks with non-trivial rotational symmetries. We first propose a systematic way of constructing orientational coordinates for such symmetric building blocks. We call the arising tensorial coordinates strong orientational coordinates (SOCs) as they fully and exclusively specify the orientation of a symmetric object. We then use SOCs to describe and quantify local and global orientational order, and spatiotemporal orientational correlations in systems of symmetric building blocks. The SOCs and the orientational order parameters developed in this work are not only useful in performing and analyzing computer simulations of symmetric molecules or particles, but can also be utilized for the efficient storage of rotational information in long trajectories of evolving many-body systems.
description: 28 pages, 10 figures, 5 tables
Heilige Macht, heilige Autorität und heiliger Zölibat. Die Vereinigten Staaten
Creators: name: Schoenherr, Richard
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 8 Nr. 10 (1972): Concilium: Internationale Zeitschrift für Theologie, Band 8, Heft 10
Saliency maps on image hierarchies
Creators: name: Vilaplana, Verónica
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper we propose two saliency models for salient object segmentation based on a hierarchical image segmentation, a tree-like structure that represents regions at different scales from the details to the whole image (e.g. gPb-UCM, BPT). The first model is based on a hierarchy of image partitions. The saliency at each level is computed on a region basis, taking into account the contrast between regions. The maps obtained for the different partitions are then integrated into a final saliency map. The second model directly works on the structure created by the segmentation algorithm, computing saliency at each node and integrating these cues in a straightforward manner into a single saliency map. We show that the proposed models produce high quality saliency maps. Objective evaluation demonstrates that the two methods achieve state-of-the-art performance in several benchmark datasets.
description: Accepted for publication in Signal Processing: Image Communications, 2015
Bithoracochaeta pacifera
Creators: name: LÖWENBERG-NETO, PETER
name: DE CARVALHO, CLAUDIO J. B.
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Muscidae
Bithoracochaeta
Bithoracochaeta pacifera

description: Bithoracochaeta pacifera (Giglio-Tos, 1893) Distribution. Mexico. MEXICO, Tuxpango, 18.8200, -97.0200 (Giglio-Tos 1893).
description: Published as part of LÖWENBERG-NETO, PETER & DE CARVALHO, CLAUDIO J. B., 2013, Muscidae (Insecta: Diptera) of Latin America and the Caribbean: geographic distribution and check-list by country, pp. 1-147 in Zootaxa 3650 (1) on page 103, DOI: 10.11646/zootaxa.3650.1.1, http://zenodo.org/record/5264631
description: {"references": ["Giglio-Tos, H. (1893) Diagnosi di nuovi generi e di nuove specie di Ditteri. VIII. Bollettino dei Musei di Zoologia ed Anatomia Comparata della Regia Universita di Torino, VIII, No. 147, 1 - 11."]}
Interview mit Silvia Pool Maag: «Integrativ beschulte Kinder haben höhere Ambitionen»
Creators: name: Pool Maag, Silvia
name: Aebischer, Christoph
Publisher: name: Zenodo
Year: 2021
Subjects: subject: Berufsleben
subject: gnd:4127591-3
subject: gnd:4077513-6
subject: gnd:4027503-6

description: Der Übertritt ins Berufsleben ist für Kinder mit besonderem Bildungsbedarf nach wie vor eine hohe Hürde. Silvia Pool Maag, Professorin für Sonderpädagogik an der PH Zürich, sieht jedoch Verbesserungen. Eine davon ist die integrative Schule, eine andere sind Job-Coaches. Oft genug machen aber schlicht gute Menschen den Unterschied. Das Interview wurde geführt von Christoph Aebischer.
description: +repphzhbib2021A
Entanglement Purification of Hypergraph States
Creators: name: Vandré, Lina
name: Gühne, Otfried
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Entanglement purification describes a primitive in quantum information processing, where several copies of noisy quantum states are distilled into few copies of nearly-pure states of high quality via local operations and classical communication. Especially in the multiparticle case, the task of entanglement purification is complicated, as many inequivalent forms of pure state entanglement exist and purification protocols need to be tailored for different target states. In this paper we present optimized protocols for the purification of hypergraph states, which form a family of multi-qubit states that are relevant from several perspectives. We start by reformulating an existing purification protocol in a graphical language. This allows for systematical optimization and we present improvements in three directions. First, one can optimize the sequences of the protocol with respect to the ordering of the parties. Second, one can use adaptive schemes, where the measurement results obtained within the protocol are used to modify the protocols. Finally, one can improve the protocol with respect to the efficiency, requiring fewer copies of noisy states to reach a certain target state.
Adiantum deflectens Mart., Icon. Pl. Crypt.
Creators: name: Kessler, Michael
name: Smith, Alan R.
name: Prado, Jefferson
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Polypodiales
Pteridaceae
Adiantum
Adiantum deflectens

description: Adiantum deflectens Mart., Icon. Pl. Crypt. 94. 1834, nom. cons.
 Range: — Mexico to Panama; Colombia and Venezuela to French Guiana and Bolivia (SC); Paraguay, Argentina, and Brazil.
 Ecology: —Rare (2 collections known), terrestrial in open vegetation; 350–500 m.
 Notes: —This species and others in the immediate group, including the related A. delicatulum, were studied by Giudice (2001). Several close relatives appear to occur in Africa and Madagascar, e.g., A. mendoncae Alston and A. madagascariense Rosehdahl. Somewhat more distantly related to the widespread A. philippense and allies.
description: Published as part of Kessler, Michael, Smith, Alan R. & Prado, Jefferson, 2017, Prodromus of a fern flora for Bolivia. XXVII. Pteridaceae, pp. 201-250 in Phytotaxa 332 (3) on page 233, DOI: 10.11646/phytotaxa.332.3.1, http://zenodo.org/record/13723685
title: Herausforderungen bei negativen Dysphotopsien
Creators: name: Neuhann, Tobias
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Die negative Dysphotopsie ist eine von mehreren visuellen Befindlichkeitsstörungen nach unkomplizierter Kataraktoperation. Patienten beschreiben den temporalen Schatten als Scheuklappe, fühlen sich unterschiedlich stark gestört und wünschen sehr häufig eine erfolgreiche Therapie.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
Kritik am Zölibatsgesetz in der katholischen Kirche seit der Periode der Reformkonzile
Creators: name: Lynch, John E.
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 8 Nr. 10 (1972): Concilium: Internationale Zeitschrift für Theologie, Band 8, Heft 10
Partial deconfinement at strong coupling on the lattice
Creators: name: Watanabe, Hiromasa
name: Bergner, Georg
name: Bodendorfer, Norbert
name: Funai, Shotaro Shiba
name: Hanada, Masanori
name: Rinaldi, Enrico
name: Schäfer, Andreas
name: Vranas, Pavlos
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: 530 Physik

description: We provide evidence for partial deconfinement — the deconfinement of a SU(M) subgroup of the SU(N) gauge group — by using lattice Monte Carlo simulations. We take matrix models as concrete examples. By appropriately fixing the gauge, we observe that the M × M submatrices deconfine. This gives direct evidence for partial deconfinement at strong coupling. We discuss the applications to QCD and holography.
title: Analyse der Glistenings und Streulichtmessung in unterschiedlichen Intraokularlinsen aus hydrophobem Acrylat
Creators: name: Khoramnia, Ramin
name: Labuz, G.
name: Knebel, D.
name: Fang, H.
name: van den Berg, T. J.
name: Yildirim, T. M.
name: Son, H.-S.
name: Auffarth, G. U.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Zielsetzung: Untersuchung der Glistenings in verschiedenen hydrophoben Intraokularlinsen (IOLs) und deren Einflüsse auf die Lichtstreuung. Methoden: Die Anfälligkeit des hydrophoben Acrylmaterials für die Entwicklung von Glistenings wurde in 6 IOL-Modellen untersucht. Mit Hilfe[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
Symmetry Remnants in the Face of Competing Interactions in Nuclei
Creators: name: Leviatan, A.
name: Macek, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: Chaotic Dynamics (nlin.CD)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Detailed description of nuclei necessitates model Hamiltonians which break most dynamical symmetries. Nevertheless, generalized notions of partial and quasi dynamical symmetries may still be applicable to selected subsets of states, amidst a complicated environment of other states. We examine such scenarios in the context of nuclear shape-phase transitions.
description: 4 pages, 2 figures, Proc. Int. Conf. on "Nuclear Structure and Dynamics III", June 14-19, 2015, Portoroz, Slovenia
title: Silikonöl-Anhaftung an hydrophobe Acryl-Intraokularlinsen: Vergleichslaborstudie einer neuen versus einer etablierten hydrophoben Acryl-Intraokularlinse
Creators: name: Auffarth, Gerd U.
name: Schickhardt, S. K.
name: Hengerer, F. H.
name: Fang, H.
name: Wang, Q.
name: Wolfe, P.
name: Jain, R.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Zielsetzung: Diese Studie vergleicht die Anhaftung von Silikonöl eines neuen hydrophoben Acryl-Intraokularlinsenmaterials, das des Clareon Modells CNA0T0, mit dem Material der etablierten AcrySof SN60WF in einer in vitro Studie. Methodik: Die Silikonöl Anhaftung wurde bei zwei IOL-Modellen,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
Creators: name: Feng, Joy Y.
name: Park, Yeojin
name: MacKman, Richard L.
name: Bannister, Roy
name: Siegel, Dustin
name: Cihlar, Tomas
name: Spahn, Jamie E.
name: Jordan, Robert
name: Menachery, Vineet D.
name: Palmiotti, Christopher A.
name: Denison, Mark R.
name: Trantcheva, Iva
name: Clarke, Michael O.
name: Leist, Sarah R.
name: Pyrc, Krzysztof
name: Babusis, Darius
name: Ray, Adrian S.
name: Sims, Amy C.
name: Sheahan, Timothy P.
name: Gralinski, Lisa E.
name: Case, James B.
name: Baric, Ralph S.
name: Graham, Rachel L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Emerging viral infections are difficult to control as heterogeneous members periodically cycle in and out of humans and zoonotic hosts, complicating the development of specific antiviral therapies and vaccines. Coronaviruses (CoVs) have a proclivity to spread rapidly into new host species causing severe disease. SARS-CoV and MERS-CoV successively emerged causing severe epidemic respiratory disease in immunologically naïve human populations throughout the globe. Broad-spectrum therapies capable of inhibiting CoV infections would address an immediate unmet medical need and could be invaluable in the treatment of emerging and endemic CoV infections. Here we show that a nucleotide prodrug GS-5734, currently in clinical development for treatment of Ebola virus disease, can inhibit SARS-CoV and MERS-CoV replication in multiple in vitro systems including primary human airway epithelial cell cultures with submicromolar IC50 values. GS-5734 was also effective against bat-CoVs, prepandemic bat-CoVs and circulating contemporary human CoV in primary human lung cells, thus demonstrating broad-spectrum anti-CoV activity. In a mouse model of SARS-CoV pathogenesis, prophylactic and early therapeutic administration of GS-5734 significantly reduced lung viral load and improved clinical signs of disease as well as respiratory functions. These data provide substantive evidence that GS-5734 may prove effective against endemic MERS-CoV in the Middle East, circulating human CoV, and possibly most importantly, emerging CoV of the future.
Mobilizing capital for responsible innovation: the role of social finance in supporting innovative projects
Creators: name: Silva, H. P.
name: Lehoux, P.
name: Sabio, R. P.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The literature on Responsible Innovation (RI) has not yet fully addressed the role played by social finance (SF) in supporting projects and organizations engaged in the production of innovations that tackle grand societal challenges. This study addresses this gap by empirically examining how SF investors select potential investees and the principles they judge important in SF. Our findings show that SF investors apply a combination of criteria to select investment projects where entrepreneurial motivations, environmental, social and governance commitments, and the nature of the impacts being generated align with their portfolio's mission. Though not all SF investors in our sample had knowledge about the concept of responsibility, they nonetheless mobilized a broad set of principles that are closely aligned with the aims and practices of RI. More research is needed to clarify the type of resources SF use to support RI and the conditions under which these resources are provided.
title: OCT vor Kataraktchirurgie
Creators: name: Hoerauf, Hans
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Aktuelle Studien unterstreichen, dass eine SD-OCT-Untersuchung im präoperativen Diagnostikstandard bei Kataraktpatienten mit einem in der Funduskopie unauffälligen Fundus einen Vorteil hinsichtlich dadurch entdeckter Pathologien bringt und ob die Qualität der Indikationsstellung für[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
Leo P: An Unquenched Very Low-Mass Galaxy
Creators: name: McQuinn, Kristen B. W.
name: Skillman, Evan D.
name: Dolphin, Andrew
name: Cannon, John M.
name: Salzer, John J.
name: Rhode, Katherine L.
name: Adams, Elizabeth A. K.
name: Berg, Danielle
name: Giovanelli, Riccardo
name: Girardi, Léo
name: Haynes, Martha P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Leo P is a low-luminosity dwarf galaxy discovered through the blind HI Arecibo Legacy Fast ALFA (ALFALFA) survey. The HI and follow-up optical observations have shown that Leo P is a gas-rich dwarf galaxy with active star formation, an underlying older population, and an extremely low oxygen abundance. We have obtained optical imaging with the Hubble Space Telescope to two magnitudes below the red clump in order to study the evolution of Leo P. We refine the distance measurement to Leo P to be 1.62+/-0.15 Mpc, based on the luminosity of the horizontal branch stars and 10 newly identified RR Lyrae candidates. This places the galaxy at the edge of the Local Group, ~0.4 Mpc from Sextans B, the nearest galaxy in the NGC 3109 association of dwarf galaxies of which Leo P is clearly a member. The star responsible for ionizing the HII region is most likely an O7V or O8V spectral type, with a stellar mass >25 Msun. The presence of this star provides observational evidence that massive stars at the upper-end of the initial mass function are capable of being formed at star formation rates as low as ~10^-5 Msun/yr. The best-fitting star formation history derived from the resolved stellar populations of Leo P using the latest PARSEC models shows a relatively constant star formation rate over the lifetime of the galaxy. The modeled luminosity characteristics of Leo P at early times are consistent with low-luminosity dSph Milky Way satellites, suggesting that Leo P is what a low-mass dSph would look like if it evolved in isolation and retained its gas. Despite the very low mass of Leo P, the imprint of reionization on its star formation history is subtle at best, and consistent with being totally negligible. The isolation of Leo P, and the total quenching of star formation of Milky Way satellites of similar mass, implies that local environment dominates the quenching of the Milky Way satellites.
description: 16 pages, 9 figures, 6 tables. Accepted to ApJ. Revised version includes light curves and additional small edits to the text
title: Aktuelle Trends in der Makulachirurgie
Creators: name: Priglinger, Siegfried G.
name: Siedlecki, J.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Vitreomakuläre Traktion – VMT: Bei der Bewertung der aktuellen Therapieoptinen für VMT ist es wichtig, den Spontanverlauf einer VMT zu kennen. John, Tzu und Kollegen konnten 2014 und 2015 zeigen, dass dieser nicht so dramatisch sein muss, wie oft befürchtet. Von 230 über 18[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII)
An enhanced version of the heat exchange algorithm with excellent energy conservation properties
Creators: name: Wirnsberger, P.
name: Frenkel, D.
name: Dellago, C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We propose a new algorithm for non-equilibrium molecular dynamics simulations of thermal gradients. The algorithm is an extension of the heat exchange algorithm developed by Hafskjold and co-workers [Mol. Phys. 80, 1389 (1993); Mol. Phys. 81, 251 (1994)], in which a certain amount of heat is added to one region and removed from another by rescaling velocities appropriately. Since the amount of added and removed heat is the same and the dynamics between velocity rescaling steps is Hamiltonian, the heat exchange algorithm is expected to conserve the energy. However, it has been reported previously that the original version of the heat exchange algorithm exhibits a pronounced drift in the total energy, the exact cause of which remained hitherto unclear. Here, we show that the energy drift is due to the truncation error arising from the operator splitting and suggest an additional coordinate integration step as a remedy. The new algorithm retains all the advantages of the original one whilst exhibiting excellent energy conservation as illustrated for a Lennard-Jones liquid and SPC/E water.
description: 8 pages, 6 figures
Klerikerehe und -zölibat in der orthodoxen Kirche
Creators: name: Kōnstantelos, Dēmētrios I.
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 8 Nr. 10 (1972): Concilium: Internationale Zeitschrift für Theologie, Band 8, Heft 10
MPEC 2024-R139 : 2024 RN4
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 RN4

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Purity and quasi-split torsors over Prüfer bases
Creators: name: Guo, Ning
name: Liu, Fei
Publisher: name: arXiv
Year: 2023
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: Primary 14F22, Secondary 14F20, 14G22, 16K50

description: We establish an analogue of the Zariski--Nagata purity theorem for finite étale covers on smooth schemes over Prüfer rings by demonstrating Auslander's flatness criterion in this non-Noetherian context. We derive an Auslander--Buchsbaum formula for general local rings, which provides a useful tool for studying the algebraic structures involved in our work. Through analysis of reflexive sheaves, we prove various purity theorems for torsors under certain group algebraic spaces, such as the reductive ones. Specifically, using results from EGAIV4 on parafactoriality on smooth schemes over normal bases, we prove the purity for cohomology groups of multiplicative type groups at this level of generality. Subsequently, we leverage the aforementioned purity results to resolve the Grothendieck--Serre conjecture for torsors under a quasi-split reductive group scheme over schemes smooth over Prüfer rings. Along the way, we also prove a version of the Nisnevich purity conjecture for quasi-split reductive group schemes in our Prüferian context, inspired by the recent work of Cesnavicius.
description: 58 pages; final version
Calculation of structure coefficients from Asymptotic derivation of a higher-order one-dimensional model for tape springs
Creators: name: Kumar, Arun
name: Audoly, Basile
name: Lestringant, Claire
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: 90506 Structural Engineering
subject: FOS: Civil engineering

description: This notes provides some details on the derivation of the structure coefficient entering in the analysis of the gradient effect in Section 5b and 5c.