Comparative in vitro study and biomechanical testing of two different magnesium alloys
Creators: name: Weizbauer, Andreas
name: Modrejewski, Christian
name: Behrens, Sabine
name: Klein, Helmut
name: Helmecke, Patrick
name: Seitz, Jan-Marten
name: Windhagen, Henning
name: Möhwald, Kai
name: Reifenrath, Janin
name: Waizy, Hazibullah
Publisher: name: London : SAGE Publications Ltd.
Year: 2014
Subjects: subject: corrosion
subject: implants
subject: In vitro
subject: magnesium
subject: orthopedic
subject: Bending strength
subject: Biomedical engineering
subject: Corrosion
subject: Degradation
subject: Dental prostheses
subject: Magnesium
subject: Magnesium alloys
subject: Medical applications
subject: Orthopedics
subject: Biomechanical testing
subject: Biomedical applications
subject: Biomedical material
subject: Four-point bending test
subject: Hank's balanced salt solutions
subject: In-vitro
subject: Osteosynthesis plate
subject: Primary stabilities
subject: Magnesium printing plates
subject: alloy
subject: balanced salt solution
subject: magnesium alloy
subject: magnesium derivative
subject: titanium
subject: unclassified drug
subject: biomaterial
subject: calcium
subject: ZEK100
subject: article
subject: biomechanics
subject: chemical structure
subject: comparative study
subject: controlled study
subject: degradation
subject: diffraction
subject: flame photometry
subject: immersion
subject: in vitro study
subject: inductively coupled plasma optical emission spectroscopy
subject: osteosynthesis
subject: priority journal
subject: scanning electron microscopy
subject: strength
subject: synchrotron radiation
subject: bone plate
subject: devices
subject: human
subject: materials testing
subject: surface property
subject: Alloys
subject: Biocompatible Materials
subject: Biomechanical Phenomena
subject: Bone Plates
subject: Calcium
subject: Fracture Fixation, Internal
subject: Humans
subject: Materials Testing
subject: Microscopy, Electron, Scanning
subject: Surface Properties
subject: Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit

description: In this in vitro study, magnesium plates of ZEK100 and MgCa0.8 alloy similar to common titanium alloy osteosynthesis plates were investigated as degradable biomedical materials with a focus on primary stability. Immersion tests were performed in Hank's Balanced Salt Solution at 37. The bending strength of the samples was determined using the four-point bending test according to ISO 9585:1990. The initial strength of the noncorroded ZEK100 plate was 11% greater than that of the MgCa0.8 plate; both were approximately 65% weaker than a titanium plate. The bending strength was determined after 48 and 96 h of immersion in Hank's Balanced Salt Solution; both magnesium alloys decreased by approximately 7% after immersion for 96 h. The degradation rate and the Mg2+ release of ZEK100 were lower than those of MgCa0.8. Strong pitting and filiform corrosion were observed in the MgCa0.8 samples after 96 h of immersion. The surface of the ZEK100 plates exhibited only small areas of filiform corrosion. The results of this in vitro study indicate that the ZEK100 alloy may be more suitable for biomedical applications. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.