cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM1 of Microbial community dynamics in an ANAMMOX reactor for piggery wastewater treatment with startup, raising nitrogen load, and stable performance
Creators: name: Huang, Qiang
name: Du, Wei-Li
name: Miao, Li-Li
name: Liu, Ying
name: Liu, Zhi-Pei
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1: Figure S1. Schematic diagram of the â UASB+SHARON+ANAMMOXâ system for piggery wastewater treatment. (1) storage tank; (2) delivery pump; (3) gas meter; (4) UASB reactor; (5) effluent tank; (6) delivery pump; (7) warm water delivery pump; (8) SHARON reactor; (9) thermostat water bath; (10) air pump; (11) effluent tank; (12) suction pump; (13) delivery pump; (14) ANAMMOX reactor; (15) warm water delivery pump; (16) effluent tank. Figure S2. Heatmap plot illustrating relative percentages of major genera (clustering shown on vertical axis) within each sample (horizon-axis clustering) from ANAMMOX bioreactor. Numbers at bottom: times when activated sludge samples were obtained. Color intensities indicate relative abundances at genus level (legend at bottom). Figure S3. Four phyla were significantly correlated to Planctomycetes in the ANAMMOX bioreactor. Figure S4. A) Neighbor-joining tree of AOB OTUs based on 16S rRNA gene fragments. B) Relative abundance of these OTUs during the entire experimental period. Dotted line indicated day 229 when effluent from SHARON was used as influent. Bootstrap values (>50%) shown on branch nodes are based on 1000 trials. Bar: evolutionary distance 0.01.
Bounce beyond Horndeski with GR asymptotics and $γ$-crossing
Creators: name: Mironov, S.
name: Rubakov, V.
name: Volkova, V.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is known that beyond Horndeski theory admits healthy bouncing cosmological solutions. However, the constructions proposed so far do not reduce to General Relativity (GR) in either infinite past or infinite future or both. The obstacle is so called $γ$-crossing, which off hand appears pathological. By working in the unitary gauge, we confirm the recent observation by Ijjas [arXiv:1710.05990] that $γ$-crossing is, in fact, healthy. On this basis we construct a spatially flat, stable bouncing Universe solution whose asymptotic past and future are described by GR with conventional massless scalar field.
description: 23 pages, journal version of the article. A minor comment has been introduced in Sec.3.2
Additional file 1: of Prevalence and risk factors of chronic obstructive pulmonary disease in Anhui Province, China: a population-based survey
Creators: name: Zha, Zhenqiu
name: Leng, Ruixue
name: Xu, Wei
name: Bao, Heling
name: Chen, Yeji
name: Fang, Liwen
name: Liu, Zhirong
name: Ye, Dongqing
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Table S1. American Association for Public Opinion Research outcome rate calculator (Panel of in-person household surveys). Table S2. General characteristics of participants included and excluded in the analysis. Table S3. Severity of COPD according to GOLD criteria. Table S4. Modified MRC dyspnea scale and GOLD ABCD assessment in patients with COPD. Table S5. Unweighted prevalence of respiratory symptoms in Patients with COPD in Anhui. Table S6. General characteristics of patients with COPD. Table S7. Unweighted awareness, diagnosis by spirometry, treatment of COPD among COPD patients. Table S8. PAFs for COPD risk factors. (DOC 172 kb)
Additional file 1: of A large cohort study identifying a novel prognosis prediction model for lung adenocarcinoma through machine learning strategies
Creators: name: Li, Yin
name: Ge, Di
name: Gu, Jie
name: Xu, Fengkai
name: Zhu, Qiaoliang
name: Lu, Chunlai
Publisher: name: figshare
Year: 2019
Subjects: Medicine
Cell Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer

description: Figure S1. Normalization of the microarray datasets from GEO. A. Before normalization. The batch effect among five datasets can be observed. B. After removal of batch effect and normalization. Figure S2. Model construction and selection. X-axis represents the number of risk models, y-axis represents the C-index, each green point represents the C-index of a particular risk model. We used red lines to connect these points. The C-indices of the model we captured were highlighted. Figure S3. 16 genes were selected by LASSO regression analysis. A. The dashed vertical line represents the optimal value of log Îť with the minimum partial likelihood deviance. B. LASSO coefficient of the 16 genes. Figure S4. Stratification analysis. TCGA stage III LUAD patients were stratified into high- and low- subgroups based the predictive signature, and high-risk group patients had poorer OS compared to low-risk group patients. Hazard Ratio: 2.89; 95% CI: 1.47 â 5.69; p-value < 0.001. Figure S5. Kaplan-Meier survival curves of recurrence-free survival (RFS) between high-risk and low-risk patients. A. TCGA LUAD patients. B. GEO LUAD patients. In both patient datasets, the RFS time of patients in the high-risk group was significantly shorter than that in the low-risk group. Figure S6. Independent validation on GSE72094 dataset. Kaplan-Meier survival analysis showing the predictive signature can separate GSE72094 LUAD patients into high- and low-risk groups with different OS (p-value < 0.0001). (DOCX 3130 kb)
D6.1 Mapping of biodiversity on selected study  areas
Creators: name: Laanisto, Lauri
name: Alos Orti, Marta Maria
name: Mattas, Konstadinos
name: Mamolos, Andreas
name: Yercan, Murad
name: Istipliler, Deniz
name: Katsiotis, Andreas
name: Nikoloudakis, Nikolaos
name: Bessai, Ann-Kathrin
name: Solovyeva, Irina
name: Xoplaki, Elena
name: Martinussen, Inger
name: Lamprinakis, Lampros
name: Miserendino, Gabriele
Publisher: name: Zenodo
Year: 2023

description: Deliverable 6.1 in the project BioValue corresponds fully with the Task 6.1 “Biodiversity - Soil and Landscape linkages” (M1-M18). The main objective of the WP6 is to analyze the effects of key environmental agents, which influence directly the agri-food value chain through agricultural and food production process, on biodiversity, drawing thus a link among the environment and biodiversity. The research in WP6 focuses on the analysis of key environmental parameters reflecting the tasks, and done for eight selected agricultural study areas located in Cyprus, Germany, Greece, Estonia, Italy, Norway, Spain, Turkey that incorporate various farm systems vis-à-vis biodiversity. The results of this analysis, which are based on landscape scale mapping of habitat diversity and heterogeneity (using CORINE land cover inventory) of the pilot study areas, will ultimately lead to an assessment and review of the linkages among environmental factors and the underutilization of genetically diverse crops in today’s agro-ecosystems.

Landscape diversity and heterogeneity in the pilot sites of this study have a clear disparity on the latitudinal gradient: southern sites tend to lack natural habitats and have been transformed into a total agricultural and urban landscapes (see Cyprus site as an example), but northern sites are highly heterogeneous landscapes with a relatively high proportion of natural habitats (see Estonian site as an example). Fully anthropogenic and irrigation-dependent land use puts the long-term sustainability of commonly used agricultural practices in hazard. Therefore selecting the right crops can make it possible to continue agriculture in long-term even if the landscape is heavily fragmented and transformed by human activities. However, also biotic factors play significant role in creating suitable conditions, especially when the selected crops are dependent on biotic interactions that can be both positive and negative. 

The diversity and heterogeneity of the surrounding landscape will need more attention of the local farmers if they want to maintain a sustainable agriculture. Also, the crop selection will have to be less robust – growing popular cash crops will not be feasible in all locations, and crops more specifically suitable for particular conditions have to be selected in the future. But that a more comprehensible approach could be conceived as an opportunity, not as a limitation.
Galactic Halos As Boson Stars
Creators: name: Lee, Jae-weon
name: Koh, In-guy
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We investigate the boson star with the self-interacting scalar field as a model of galactic halos. The model has slightly increasing rotation curves and allows wider ranges of the mass($m$) and coupling($λ$) of the halo dark matter particle than the non-interacting model previously suggested(ref.\cite{sin1}). Two quantities are related by $λ^{\frac{1}{2}} (m_p/m)^2\st{>}{\sim} 10^{50}$.
description: 15 pages. Standard Latex file with 2 tex figures. Revised version to be published in Phy. Rev. D. (Stability arguments are added.)
title: The induction and characterization of chromosomal translocations in anopheles Gambiae species A
Creators: name: Akiyama, J
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 1975

description: With the possibility of their eventual use as control agents in mind, attempts were made to isolate and characterize reciprocal chromosomal translocations in species A of the Anopheles gambiae complex. Translocations were induced in males with X-rays and determined by testing for the occurrence of inherited partial sterility. Hatching rate was the principal criterion used for the designation of karyotype. Young males of a Y-autosomal translocation line (TYF-5) were re-irradiated with X-rays at 4000 rads. Several further interchanges were isolated. Among 120 tested F 1 males, four 3-chrornosome double translocation lines were obtained. These lines were found to transmit their characteristic partial sterility (75%) to all their sons when outcrossed to the wild-type, but none of the daughters inherited partial sterility. Comparative studies showed that 3-chromosome doubly translocated males displayed fitness comparable with the wildtype males. Among 92 F1 daughters tested, 8 lines showing regular inheritance of partial sterility were established. In 5 of these lines the presence of translocations was confirmed cytologically. Four were shown to involve autosome-autosome translocations and one involved an X-autosome interchange. The fertilities of these lines were found to be significantly higher than 50%. The merits of using comparatively low radiation dosage are discussed and tested by attempting to induce translocations using only 1,500 rads. From a resulting number of 154 F1 males and females which were outcrossed 7 partially sterile lines were isolated. One of these proved to be a reciprocal interchange between the two autosomes. The remaining 6 lines, when outcrossed to the wild-type, showed a rather low frequency of semisterility. Efforts were made to produce autosomal translocation homozygotes, bllt without success. For all the 5 lines investigated, data obtained from hatching rates of intercrossed heterozygotes suggested that translocation homozygotes would be lethal. In future isolation of autosomal translocation homozygotes it will be essential to employ a team of workers to perform all the requisite tasks of creating, selecting and evaluating strains suitable for genetic control purposes. The probable effectiveness of male-linked translocations is discussed in the light of experimental experiences.
Supporting information: Structural colours in the frond of Microsorum thailandicum from Structural colours in the frond of Microsorum thailandicum
Creators: name: Steiner, Lisa Maria
name: Ogawa, Yu
name: Villads Egede Johansen
name: Lundquist, Clive
name: Whitney, Heather
name: Vignolini, Silvia
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 90301 Biomaterials
subject: FOS: Medical engineering

description: Blue and near-ultraviolet structural colours have often been reported in understorey plants living in deep shade. While this intense blue coloration is very catchy to the eye of a human observer, there are cases in which structural colours can be hidden either by the scattered light interacting with pigments or because they are found in unexpected positions in the plants. Here, we show that the fronds of Microsorum thailandicum produce structural coloration on both the adaxial and abaxial epidermal surface. While cellulose helicoidal structures are responsible for this coloration in both epidermal layers, the reflected colours are consistently different: an intense blue reflection is found in the adaxial epidermis while red-shifted and less intense colours are observed in the abaxial epidermis, possibly suggesting photo-adaptation of the plant to the light environment. By comparing the optical properties of the fern with its anatomy we computed the theoretical reflection accounting for the presence of disorder in the cellulose helicoidal architecture.
Another X-ray-Discovered Poor Cluster of Galaxies Associated with CL 0016+16
Creators: name: Hughes, John P.
name: Birkinshaw, Mark
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report optical spectroscopic observations of RX J0018.8+1602, a ROSAT X-ray source proposed to be an intermediate redshift cluster of galaxies. Our observations confirm the identification of RX J0018.8+1602 and provide measurements of its mean radial velocity (z=0.5406 +/- 0.0006) and velocity dispersion (sigma_p = 200 [+110, -80] km/s). This is the second poor cluster that has been found to be a companion to CL 0016+16 (z=0.5455), the other one being RX J0018.3+1618 (z=0.5506). The 0.2-2 keV band source-frame X-ray luminosity summed over both companion clusters is 5E44 ergs/s, which is a significant fraction, ~23%, of the X-ray luminosity of the main cluster. The companions are located at angular distances of 10 arcmin to 25 arcmin (minimum physical scales of 5 Mpc to 12 Mpc) from CL 0016+16 and we propose that they represent a new large-scale component of the X-ray emission from clusters of galaxies. Similar low X-ray luminosity poor clusters surrounding nearby Abell clusters can explain the excess power observed in the angular cross-correlation function between Abell clusters and the X-ray background on inferred physical scales of 14--20 Mpc (Soltan et al. 1996).
description: 16 pages, including 3 postscript figs, LaTeX. To appear in ApJ
Specific circulating miRNA are associated with plasma lipids in a healthy American cohort.
Creators: name: Evans, Levi
name: Bennett, Brian J.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310202
subject: Biological network analysis
classificationCode: 310204
subject: Genomics and transcriptomics
classificationCode: 310208
subject: Translational and applied bioinformatics

description: microRNA sequencing, cardiometabolic phenotypes, and diet data were collected from a healthy American cohort and analyzed through classical regression and hierarchical clustering techniques.
Probing Supergravity Grand Unification in the Brookhaven g-2 Experiment
Creators: name: Chattopadhyay, U.
name: Nath, Pran
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A quantitative analysis of $\amu\equiv{1\over 2}(g-2)_μ$ within the framework of Supergravity Grand Unification and radiative breaking of the electro-weak symmetry is given. It is found that $a_μ^{SUSY}$ is dominated by the chiral interference term from the light chargino exchange, and that this term carries a signature which correlates strongly with the sign of $μ$. Thus as a rule $a_μ^{SUSY}>0$ for $μ>0$ and $a_μ^{SUSY}<0$ for $μ<0$ with very few exceptions when tan$β\sim 1$. At the quantitative level it is shown that if the E821 BNL experiment can reach the expected sensitivity of $4\times 10^{-10}$ and there is a reduction in the hadronic error by a factor of four or more, then the experiment will explore a majority of the parameter space in $ m_0-m_{\tilde g}$ plane in the region $m_0\lsim 400$ GeV, $m_{\tilde g}\lsim 700$ GeV for $\tanbeta \gsim 10$ assuming the experiment will not discard the Standard Model result within its $2σ$ uncertainty limit. For smaller $\tanbeta$, the SUSY reach of E821 will still be considerable. Further, if no effect within $2 σ$ limit of the Standard Model value is seen, then large $\tanbeta$ scenarios will be severely constrained within the current naturalness criterion, ie., $m_0, m_{\tilde g}\lsim 1$ TeV.
description: 27 pages, Latex, uuencoded figure file to be obtained and processed separately for two figures. Figures may also be sent on request by mail
S1 -S4 from The structure of temperate phage-bacteria-infection networks changes with the phylogenetic distance of the host bacteria
Creators: name: Wendling, Carolin C.
name: Goehlich, Henry
name: Roth, Olivia
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: S1: Methods; S2: Strains and their derived temperate phages used for the LRN (Table S1) and the HRN (Table S2); S3: Modular Display of the HRN; S4: Correlation between genetic distances of a phage's original host and the genetic distances of all hosts that phage can infect
Charged Higgs Contribution into (t b_bar)-pair Production in Hadronic Collisions
Creators: name: Foursa, M. V.
name: Murashev, D. A.
name: Slabospitsky, S. R.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the charged Higgs boson contribution into $t\bar b$-pair production in pp-collisions at LHC. It is shown that due to the $\cz$-boson exchange the total yield of $t\bar b$ is modified significantly for small and large values of $\tanβ$. However, for the small values of $\tanβ$ one should expect also the production of right-polarized top quark contrary to pure left-polarized t-quark production through $W^{\pm}$-boson exchange only. This fact provides a possibility to separate $H^{\pm}$ and $W^{\pm}$ contributions by means of the investigations of angular distributions of top decay products. The detailed simulation of the signal and relevant background processes is performed.
description: 20 pages, 8 figures; minor corrections in text and references
Signatures of the genuine and matter-induced components of the CP violation asymmetry in neutrino oscillations
Creators: name: Bernabeu, J.
name: Segarra, A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: CP asymmetries for neutrino oscillations in matter can be disentangled into the matter-induced CPT-odd (T-invariant) component and the genuine T-odd (CPT-invariant) component. For their understanding in terms of the relevant ingredients, we develop a new perturbative expansion in both $Δm^2_{21},\, |a| \ll |Δm^2_{31}|$ without any assumptions between $Δm^2_{21}$ and $a$, and study the subtleties of the vacuum limit in the two terms of the CP asymmetry, moving from the CPT-invariant vacuum limit $a \to 0$ to the T-invariant limit $Δm^2_{21} \to 0$. In the experimental region of terrestrial accelerator neutrinos, we calculate their approximate expressions from which we prove that, at medium baselines, the CPT-odd component is small and nearly $δ$-independent, so it can be subtracted from the experimental CP asymmetry as a theoretical background, provided the hierarchy is known. At long baselines, on the other hand, we find that (i) a Hierarchy-odd term in the CPT-odd component dominates the CP asymmetry for energies above the first oscillation node, and (ii) the CPT-odd term vanishes, independent of the CP phase $δ$, at $E =0.92~\mathrm{GeV}\,(L/1300~\mathrm{km})$ near the second oscillation maximum, where the T-odd term is almost maximal and proportional to $\sinδ$. A measurement of the CP asymmetry in these energy regions would thus provide separate information on (i) the neutrino mass ordering, and (ii) direct evidence of genuine CP violation in the lepton sector.
description: 27 pages, 10 figures, 2 tables
Supplementary Material from Reflections on iridescent neck and breast feathers of the peacock, Pavo cristatus
Creators: name: Freyer, Pascal
name: Wilts, Bodo D.
name: Doekele G. Stavenga
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 90301 Biomaterials
subject: FOS: Medical engineering
subject: 30402 Biomolecular Modelling and Design
subject: FOS: Chemical sciences

description: The blue neck and breast feathers of the peacock are structurally coloured due to an intricate photonic crystal structure in the barbules consisting of a two-dimensionally ordered rectangular lattice of melanosomes (melanin rodlets) and air channels embedded in a keratin matrix. We here investigate the feather coloration by performing microspectrophotometry, imaging scatterometry and angle-dependent reflectance measurements. Using previously determined wavelength-dependent refractive indices of melanin and keratin, we interpret the spectral and spatial reflection characteristics by comparing the measured spectra to calculated spectra by effective-medium multilayer and full three-dimensional finite-difference time-domain modelling. Both modelling methods yield similar reflectance spectra indicating that simple multilayer modelling is adequate for a direct understanding of the brilliant coloration of peacock feathers.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Cart. 190 (11 H 75), 316 folios, f. 0235v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0235v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0235v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Beratung als Instrument für mehr Naturschutz in der Landwirtschaft : Evaluierung des Beratungsangebotes im Verbundprojekt „Rotmilan – Land zum Leben“
Creators: name: Böhner, Hanna
name: Schmidt, Thomas
name: Böhner, Hanna
name: Schmidt, Thomas
Publisher: name: Unknown
Year: 2019
Subjects: subject: Environmental Economics and Policy
subject: Beratung
subject: Agrarumweltmaßnahmen
subject: Rotmilan
subject: Deutschland
subject: Advice
subject: Agri-environmental measures
subject: Red Kite
subject: Germany

description: From 2014 to 2018, within the scope of the "Rotmilan – Land zum Leben" joint project, more than 880 farms were given advice on the implementation of red-kite-friendly agriculture in eight regions of Germany. The main objective was to improve food availability for red kites on agricul-tural land. During the entire project period, it was possible to increase the area where measures were applied, from approx. 1,000 ha to more than 13,000 ha/year. Following an initial evaluation by Schmidt und Breitsameter (2015) on the advice given to farmers, the consultants and farm representatives – including those that did not receive any advice – were interviewed on their experiences and perspectives. The focus was on the motivation to participate in the counselling and its effects, as well as the expectations for nature conservation counselling. In summary, the following six core statements can be derived from the results: (1) Suitable funding programmes are a prerequisite for target-oriented implementation of nature conservation measures on agricultural land. (2) Advisory services promote the implementation of measures by attracting new farms to partic-ipate and increasing the amount of land involved. (3) Long-term and constant advisory services offered enable the continuous acquisition of new farms and the development of trust and cooperation. (4) Practical support in the implementation of measures, follow-up advice and the communica-tion of successful measures by the advisory institution are important components of the advisory activity. (5) Region-specific features of the advisory services are derived from the available funding measures, the characteristics of the advisory institution and advisors as well as the agricultural structure. (6) Advisory support promotes the quality of the implemented measures, thus the success of the measures cannot be measured solely on the basis of the area covered by the measures. The study reveals that advising farmers is an important instrument for the implementation of nature conservation measures. Advice transfers nature conservation expertise into land man-agement and sensitises the actors. Moreover, it offers support during the implementation of measures. The basics requirements for an effective advisory service, however, are sufficiently financed means for measures, adapted to both region-specific biodiversity targets and agricultur-al requirements.
description: DOI:10.3220/WP1571042046000
Central and peripheral mechanism of MOTS-c attenuates pain hypersensitivity in a mice model of inflammatory pain
Creators: name: Wang, Zhe
name: Yang, Long
name: Xu, Lingfei
name: Liao, Jinglei
name: Lu, Ping
name: Jiang, Jinhong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Inflammatory pain is caused by damaged tissue or noxious stimuli, accompanied by the release of inflammatory mediators that often leads to severe hyperalgesia and allodynia with limited therapy options. Recently, a novel mitochondrial-derived peptide (named MOTS-c) was reported to regulate obesity, metabolic homeostasis and inflammatory response. The aim of this study was to investigate the effects of MOTS-c and its related regulatory mechanisms involved in inflammatory pain. Male Kunming mice (8–10 weeks-old) were intraplantar injected with formalin, capsaicin, λ-Carrageenan and complete Freund adjuvant (CFA) to establish acute and chronic inflammatory pain. The effects of MOTS-c on the above inflammatory pain mice and its underlying mechanisms were examined by behavioral tests, quantitative polymerase chain reaction (qPCR), western blotting, enzyme linked immunosorbent assay (ELISA), immunohistochemistry (IHC) and immunofluorescence (IF). Behavioral experiments investigated the potential beneficial effects of MOTS-c on multiple acute and chronic inflammatory pain in mice. The results showed that MOTS-c treatment produced potent anti-allodynic effects in formalin-induced acute inflammatory pain, capsaicin-induced nocifensive behaviors and λ-Carrageenan/CFA-induced chronic inflammatory pain model. Further mechanistic studies revealed that central MOTS-c treatment significantly ameliorated CFA-evoked the release of inflammatory factors and activation of glial cells and neurons in the spinal dorsal horn. Moreover, peripheral MOTS-c treatment reduced CFA-evoked inflammatory responses in the surface structure of hindpaw skin, accompanied by inhibiting excitation of peripheral calcitonin gene-related peptide (CGRP) and P2X3 nociceptive neurons. The present study indicates that MOTS-c may serve as a promising therapeutic target for inflammatory pain.
Scanning the Topological Sectors of the QCD Vacuum with Hybrid Monte Carlo
Creators: name: Alles, B.
name: Bali, G.
name: D'Elia, M.
name: Di Giacomo, A.
name: Eicker, N.
name: Guesken, S.
name: Hoeber, H.
name: Lippert, Th.
name: Schilling, K.
name: Spitz, A.
name: Struckmann, T.
name: Ueberholz, P.
name: Viehoff, J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We address a long standing issue and determine the decorrelation efficiency of the Hybrid Monte Carlo algorithm (HMC), for full QCD with Wilson fermions, with respect to vacuum topology. On the basis of five state-of-the art QCD vacuum field ensembles (with 3000 to 5000 trajectories each and m_pi/m_rho-ratios in the regime >0.56, for two sea quark flavours) we are able to establish, for the first time, that HMC provides sufficient tunneling between the different topological sectors of QCD. This will have an important bearing on the prospect to determine, by lattice techniques, the topological susceptibility of the vacuum, and topology sensitive quantities like the spin content of the proton, or the eta' mass.
description: 5 pages, 4 eps-figures
On the observation of $e^+e^-\to b \bar{b}Z^0$ at LEP II with two Higgs doublets
Creators: name: Chang, Chao-Hsi
name: Ding, Yi-Bing
name: Li, Xue-Qian
name: Wang, Jian-Xiong
name: Xie, Yue-Hong
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study possible observational effects of the two Higgs doublets in the $e^+e^- \to b \bar{b} Z^0$ at the LEP II energy. We have found that the observational values can be obviously different from that predicted by the minimal Standard Model (MSM), but the results depend on the parameters of the extended model. The possibilities of the observation are discussed in some details.
description: 13 pages
Observation of a Fine Structure in $e^+e^- \to$ hadrons Production at the Nucleon-antinucleon Threshold
Creators: name: 3 Collaboration
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A study of hadron production at the nucleon-antinucleon threshold has been performed with the CMD-3 detector at the VEPP-2000 $e^+e^-$ collider. A very fast rise with about 1 MeV width has been observed in the $e^+e^- \to p\bar p$ cross section. A sharp drop in the $e^+e^- \to 3(π^+π^-)$ cross section has been confirmed and found to have a less than 2 MeV width, in agreement with the observed fast rise of the $e^+e^- \to p\bar p$ cross section. For the first time a similar sharp drop is demonstrated in the $e^+e^- \to K^+K^-π^+π^-$ cross section. The behavior of the $e^+e^- \to 3(π^+π^-),~ K^+K^-π^+π^-$ cross sections cannot be explained by an interference of any resonance amplitude with continuum, therefore this phenomenon cannot be due to a narrow near-threshold resonance. No such structure has been observed in the $e^+e^- \to 2(π^+π^-)$ cross section.
description: 7 pages, 5 figures
Additional file 1: of Carbohydrate, glutathione, and polyamine metabolism are central to Aspergillus flavus oxidative stress responses over time
Creators: name: Fountain, Jake
name: Yang, Liming
name: Pandey, Manish
name: Bajaj, Prasad
name: Alexander, Danny
name: Chen, Sixue
name: Kemerait, Robert
name: Varshney, Rajeev
name: Guo, Baozhu
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Figure S1. Thin layer chromatograph (TLC) of aflatoxins from culture medium extracts. Culture medium from each isolate were filtered and saved for use in aflatoxin quantification. Following extraction, samples from each isolate and treatment were developed with a TLC. Aflatoxins B1 and B2 can be observed on the TLC. Treatments are indicated below for each isolate, stress condition, and timepoint (DAI: days after inoculation). Fluorescence of the aflatoxins is visualized here using ultraviolet light (365 nm). Figure S2. Metabolomics experiment design. Two isolates of Aspergillus flavus, AF13 (highly aflatoxigenic and oxidative stress tolerant) and NRRL3357 (moderate to highly aflatoxigenic and moderately oxidative stress tolerant), were grown in yeast extract sucrose (YES) medium supplemented with either 0 or 15 mM H2O2. Samples were collected at 4 and 7 days after inoculation (DAI). Five biological replicates (n = 5, N = 40) were performed for each isolate, treatment, and time point combination. Statistical comparisons are indicated by the colored arrows with blue indicating oxidative stress effect comparisons, red indicating time effects, and green indicating isolate/genotype effects. (DOCX 842 kb)
Spacetime and dark matter from spontaneous breaking of Lorentz symmetry
Creators: name: Złośnik, Tom
name: Urban, Federico
name: Marzola, Luca
name: Koivisto, Tomi
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is shown that a spontaneously-broken gauge theory of the Lorentz group contains Ashtekar's chiral formulation of General Relativity accompanied by dust. From this perspective, gravity is described entirely by a connection $ω$ valued in the Lie algebra of the complexified Lorentz group and a Lorentz-charged scalar field $τ$. The model is "pre-geometric" in the sense that the spacetime metric may be constructed only in the symmetry-broken regime. We speculate on the extent to which this dust may account for dark matter and on the behaviour of the theory in regimes where the symmetry is not broken.
description: v2 with minor edits, as published
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia
Creators: name: Opoka, Robert O.
name: Ndugwa, Christopher
name: Latham, Teresa
name: Lane, Adam
name: Hume, Heather
name: Kasirye, Phillip
name: Hodges, James S.
name: Ware, Russell E.
name: Chandy C. John
Publisher: name: Health Research Alliance
Year: 2018
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown. In vitro studies suggest hydroxyurea could increase malaria severity, and hydroxyurea-associated neutropenia could worsen infections. NOHARM (Novel use Of Hydroxyurea in an African Region with Malaria) was a randomized, double-blinded, placebo-controlled trial conducted in malaria-endemic Uganda, comparing hydroxyurea to placebo at 20 ± 2.5 mg/kg per day for 12 months. The primary outcome was incidence of clinical malaria. Secondary outcomes included SCA-related adverse events (AEs), clinical and laboratory effects, and hematological toxicities. Children received either hydroxyurea (N = 104) or placebo (N = 103). Malaria incidence did not differ between children on hydroxyurea (0.05 episodes per child per year; 95% confidence interval [0.02, 0.13]) vs placebo (0.07 episodes per child per year [0.03, 0.16]); the hydroxyurea/placebo malaria incidence rate ratio was 0.7 ([0.2, 2.7]; P = .61). Time to infection also did not differ significantly between treatment arms. A composite SCA-related clinical outcome (vaso-occlusive painful crisis, dactylitis, acute chest syndrome, splenic sequestration, or blood transfusion) was less frequent with hydroxyurea (45%) than placebo (69%; P = .001). Children receiving hydroxyurea had significantly increased hemoglobin concentration and fetal hemoglobin, with decreased leukocytes and reticulocytes. Serious AEs, sepsis episodes, and dose-limiting toxicities were similar between treatment arms. Three deaths occurred (2 hydroxyurea, 1 placebo, and none from malaria). Hydroxyurea treatment appears safe for children with SCA living in malaria-endemic sub-Saharan Africa, without increased severe malaria, infections, or AEs. Hydroxyurea provides SCA-related laboratory and clinical efficacy, but optimal dosing and monitoring regimens for Africa remain undefined.
This trial was registered at www.clinicaltrials.gov as #NCT01976416. Protocol approval was obtained from the institutional review boards of Makerere University School of Medicine, Indiana University, University of Minnesota, and Cincinnati Children's Hospital, as well as the Uganda National Drug Authority and Uganda National Council for Science and Technology.
Induced Compton Scattering in Gigahertz Peak Spectrum Sources
Creators: name: Kuncic, Z.
name: Bicknell, G. V.
name: Dopita, M. A.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We revisit the shocked shell model for the class of Active Galactic Nuclei known as Gigahertz Peak Spectrum sources, incorporating new observational data on the radiation brightness temperatures. We argue that in addition to free-free absorption, induced Compton scattering will also have an important effect in forming the ~GHz peak and in shaping the radio spectra that characterize these sources. Indeed, our arguments suggest that GPS sources may provide the first real evidence for the role of induced Compton scattering in extragalactic radio sources.
description: 12 pages, 1 figure, AAS LaTeX style with epsf, to appear in ApJ Letters
Kink far below the Fermi level reveals new electron-magnon scattering channel in Fe
Creators: name: Młyńczak, E.
name: Müller, M. C. T. D.
name: Gospodarič, P.
name: Heider, T.
name: Aguilera, I.
name: Bihlmayer, G.
name: Gehlmann, M.
name: Jugovac, M.
name: Zamborlini, G.
name: Tusche, C.
name: Suga, S.
name: Feyer, V.
name: Plucinski, L.
name: Friedrich, C.
name: Blügel, S.
name: Schneider, C. M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Many properties of real materials can be modeled using ab initio methods within a single-particle picture. However, for an accurate theoretical treatment of excited states, it is necessary to describe electron-electron correlations including interactions with bosons: phonons, plasmons, or magnons. In this work, by comparing spin- and momentum-resolved photoemission spectroscopy measurements to many-body calculations carried out with a newly developed first-principles method, we show that a kink in the electronic band dispersion of a ferromagnetic material can occur at much deeper binding energies than expected (E_b=1.5 eV). We demonstrate that the observed spectral signature reflects the formation of a many-body state that includes a photohole bound to a coherent superposition of renormalized spin-flip excitations. The existence of such a many-body state sheds new light on the physics of the electron-magnon interaction which is essential in fields such as spintronics and Fe-based superconductivity.
description: 6 pages, 2 figures
Additional file 3: of Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance
Creators: name: Zhang, Hui
name: Fredericks, Tricia
name: Xiong, Gaofeng
name: Qi, Yifei
name: Rychahou, Piotr
name: Li, Jia-Da
name: Pihlajaniemi, Taina
name: Xu, Wei
name: Xu, Ren
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology

description: Figure S3. Immunofluorescence staining analyzes collagen XIII expression, EdU labeling, and caspase 3 activation. a 2D culture fluorescent microscopy images of MCF-10A control and Col13 overexpression cells. Flag (green), dapi (blue) and merged images. Scale bar: 20 μm. b EdU staining fluorescent microscopy images of MCF-10A control and Col13 overexpression cells. Representative image was on day6 of 3D culture. EdU (green), dapi (blue) and merged images. Scale bar: 20 μm. c The images (left) stand for caspase3 3D fluorescent staining and the bar graph (right) shows the ratio of caspase3 positive to total cells. Caspase3 (green), dapi (blue). Scale bar: 20 μm. Data are presented as the mean ± s.e.m. (n = 20); p = 0.098. (PDF 4348 kb)
Transverse Muon Polarization in $K^{\pm}\toπ^0μ^{\pm}ν$ Decay Induced by the Two-Photon Final-State Interaction
Creators: name: Efrosinin, V. P.
name: Khriplovich, I. B.
name: Kirilin, G. G.
name: Kudenko, Yu. G.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We calculate the transverse muon polarization in the decay $K^{\pm}\toπ^0μ^{\pm}ν$ induced by the electromagnetic two-photon final-state interaction. For the central part of the Dalitz plot the typical value of this polarization is about $4\times 10^{-6}$.
description: 10 pages, 4 figures
NS fivebranes in type 0 string theory
Creators: name: Craps, Ben
name: Roose, Frederik
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The massless degrees of freedom of type 0 NS5-branes are derived. A non-chiral, purely bosonic spectrum is found in both type 0A and 0B. This non-chirality is confirmed by a one-loop computation in the bulk. Some puzzles concerning type 0B S-duality are pointed out in this context. An interpretation of the spectra in terms of ``type 0 little strings'' is proposed.
description: LaTeX, 12 pages, no figures; v3: section on S-duality revised, references added, to be published in JHEP
Is the Universe Homogeneous? (On Large Scales)
Creators: name: Guzzo, Luigi
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: I critically discuss in a pedagogical and phenomenological way a few crucial tests challenging the claims by Pietronero and collaborators that there is no evidence from available galaxy catalogues that the Universe is actually homogeneous above a certain scale. In a series of papers, these authors assert that observations are consistent with a fractal distribution of objects extending to the limit of the present data. I show that while galaxies are indeed clustered in a scale-free way on small and intermediate scales, this behaviour does not continue indefinitely. Although the specific wavelength at which the galaxy distribution apparently turns to homogeneity is dangerously close to the size of the largest samples presently available, there are serious hints suggesting that this turnover is real and that its effects are detected in the behaviour of statistical estimators. The most recent claims of a continuing fractal hierarchy up to scales of several hundreds Mpc seem to be abscribable to the use of incomplete samples or to an improper treatment of otherwise high- quality data sets. The fractal perspective, nevertheless, can represent a fruitful way to look at the clustering properties of galaxies, when properly coupled to the traditional gravitational instability scenario. In the last part of this paper I therefore try to clarify, at a very simple level, some of the confusion existing on the actual scaling properties of the galaxy distribution. In this context, I shall discuss how these can provide hints on the evolution of the large-scale structure of the Universe, when one properly takes into account the effect of both initial conditions and nonlinear gravitational growth in producing the presently observed distribution.
description: 27 pages, New Astronomy, in press (2, 517). Full html version available at http://pigeon.elsevier.nl/journals/newast/jnl/menu.htm . Original colour figures available also at ftp://antares.merate.mi.astro.it/pub/guzzo/NA
MS5 Open-Earth-Monitor EU and global case studies 1st release
Creators: name: Hengl, Tomislav
name: Ehujuo, Nkem
name: Santiago, Ferrer
Publisher: name: Zenodo
Year: 2024

description: The Earth Monitor Web-App and data sets primarily aim at serving third parties from the thirty two use-cases, which are also aligned with the EU programmes / objectives. Several tools have been implemented and released, most importantly the Tier 1 data geoportal has been published (https://app.EarthMonitor.org) — this will be the central landing page for all most significant layers and requires less specialized knowledge (i.e. a service of one–click operation to watch a geostory; follow link to find out more about the data & science behind). The Open-Earth-Monitor App will remain the central access point (for simplicity) where all targeted communities / use cases can quickly find and visualize project products produced by all partners in the consortium (1-mouse-click to get engaged). We find it important that the app is simple to use, self-explanatory and requires no professional training. This way we can maximize the impact and potentially reach all EU citizens. In addition to the Tier-1 App, a second version of the Tier 2 data portal https://OpenLandMap.org has been published and several releases of the OpenEO software including the sits pkg integration. A video recording of the public launch of the Open-Earth-Monitor App which explains all targeted functionality is also available via our Youtube channel.