cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Making "Enemies:" Industry-State Subterfuge and the Social Construction of US Antidumping and Countervailing Duty Policy, 1960-1988
Creators: name: Bassney, John
Publisher: name: University of Chicago
Year: 2022

description: The few scholars who have directly studied the history of US “non-market economy” (NME) antidumping and countervailing duty policy explain its development as either an ideological relic of the Cold War or as a case of business politics. Statistical, historical, legal, and interview data indicate that the development of NME policy was not a result of Cold War ideology or business politics, but instead part of a larger political project by an incumbent US steel industry to receive relief from imports. Steel initially advocated for import quotas, but a semi-autonomous US state refused out of fear of foreign retaliation. The steel industry and the state used the discursive strategy of subterfuge to balance these competing interests.
Performance of attack strategies on modular networks
Creators: name: da Cunha, Bruno Requião
name: Gonçalves, Sebastián
Publisher: name: arXiv
Year: 2016
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Vulnerabilities of complex networks have became a trend topic in complex systems recently due to its real world applications. Most real networks tend to be very fragile to high betweenness adaptive attacks. However, recent contributions have shown the importance of interconnected nodes in the integrity of networks and module-based attacks have appeared promising when compared to traditional malicious non-adaptive attacks. In the present work we deeply explore the trade-off associated with attack procedures, introducing a generalized robustness measure and presenting an attack performance index that takes into account both robustness of the network against the attack and the run-time needed to obtained the list of targeted nodes for the attack. Besides, we introduce the concept of deactivation point aimed to mark the point at which the network stops to function properly. We then show empirically that non-adaptive module-based attacks perform better than high degree and betweenness adaptive attacks in networks with well defined community structures and consequent high modularity.
description: 14 pages, 4 figures, pre-print
Discovery of novel natural products as rhodesain inhibitors for human African trypanosomiasis using in silico techniques
Creators: name: Elrufaie, Hisham A.
name: Mohamed, Linda M.
name: Hamd, Aya Y.
name: Bala, Noor A.
name: Elbadawi, Fatima A.
name: Ghaboosh, Hiba
name: Alzain, Abdulrahim A.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: classificationCode: 29999
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Cancer
classificationCode: 110309
subject: Infectious Diseases
subject: FOS: Health sciences

description: Human African Trypanosomiasis (HAT) or sleeping sickness is caused by the Trypanosoma brucei rhodesiense, a subspecies of the Trypanosomatide family. The parasite is associated with high morbidity and mortality rate in both animals and humans, claimed to be more fatal than other vector-transmitted diseases such as malaria. The majority of existing medications are highly toxic, not effective in the late chronic phase of the disease, and require maximum dosages to fully eradicate the parasite. In this study, we used computational methods to find out natural products that inhibit the Rhodesain, a parasitic enzyme that plays an important role in the parasite's pathogenicity, multiplication, and ability to pass through the host's blood-brain barrier. A library of 270540 natural products from ZINC databases was processed by using e-pharmacophore hypnosis and screening procedures, molecular docking, ADMET processes, and MM-GBSA calculations. This led to the identification of 3 compounds (ZINC000096269390, ZINC000035485292, and ZINC000035485242) which were then subjected to molecular dynamics. The findings of this study showed excellent binding affinity and stability toward the Rhodesain and suggest they may be a hopeful treatment for HAT in the future if further clinical trials were performed. Communicated by Ramaswamy H. Sarma
Periodically-driven Kondo impurity in nonequilibrium steady states
Creators: name: Iwahori, Koudai
name: Kawakami, Norio
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the nonequilibrium dynamics of a periodically-driven anisotropic Kondo impurity model. The periodic time dependence is introduced for a local magnetic field which couples to the impurity spin and also for an in-plane exchange interaction. We obtain the exact results on the time evolution for arbitrary periodic time dependence at the special point in the parameter space known as the Toulouse limit. We first consider a specific case where the local magnetic field is periodically switched on and off. When the driving period is much shorter than the inverse of the Kondo temperature, an intriguing oscillating behavior (resonance phenomenon) emerges in the time average of the impurity spin polarization with increasing the local magnetic field intensity. By taking the high frequency limit of the external driving, we elucidate that the system recovers the translational invariance in time and can be described by a mixture of the zero-temperature and infinite-temperature properties. In certain cases, the system is governed by either the zero-temperature or infinite-temperature properties, and therefore can be properly described by the corresponding equilibrium state.
description: 11 pages, 3 figures
Positron cooling via inelastic collisions in CF$_4$ and N$_2$ gases
Creators: name: Swann, A. R.
name: Green, D. G.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Positron cooling via inelastic collisions in CF$_4$ and N$_2$ gases is simulated, including positron-positron interactions. Owing to the molecular symmetries, cooling is assumed to be chiefly due to energy loss via vibrational (rotational) excitations for CF$_4$ (N$_2$). For CF$_4$, it is found that the inclusion of the dipole-inactive $ν_1$ mode, in addition to the dipole-active modes $ν_3$ and $ν_4$, can provide room-temperature thermalization and an accurate cooling timescale. Combination cooling enabled by the $ν_1$ mode, and positron-positron interactions both contribute to the Maxwellianization of the positron momentum distribution. For both gases the evolution of the positron temperature is found to be in excellent agreement with experiment.
description: 6 pages, 7 figures
DOTmark - A Benchmark for Discrete Optimal Transport
Creators: name: Schrieber, Jörn
name: Schuhmacher, Dominic
name: Gottschlich, Carsten
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optimization and Control (math.OC)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 90-08, 90-04, 90C05, 90C08

description: The Wasserstein metric or earth mover's distance (EMD) is a useful tool in statistics, machine learning and computer science with many applications to biological or medical imaging, among others. Especially in the light of increasingly complex data, the computation of these distances via optimal transport is often the limiting factor. Inspired by this challenge, a variety of new approaches to optimal transport has been proposed in recent years and along with these new methods comes the need for a meaningful comparison. In this paper, we introduce a benchmark for discrete optimal transport, called DOTmark, which is designed to serve as a neutral collection of problems, where discrete optimal transport methods can be tested, compared to one another, and brought to their limits on large-scale instances. It consists of a variety of grayscale images, in various resolutions and classes, such as several types of randomly generated images, classical test images and real data from microscopy. Along with the DOTmark we present a survey and a performance test for a cross section of established methods ranging from more traditional algorithms, such as the transportation simplex, to recently developed approaches, such as the shielding neighborhood method, and including also a comparison with commercial solvers.
Directional Multivariate Extremes in Environmental Phenomena
Creators: name: Torres, Raúl
name: De Michele, Carlo
name: Laniado, Henry
name: Lillo, Rosa E.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Several environmental phenomena can be described by different correlated variables that must be considered jointly in order to be more representative of the nature of these phenomena. For such events, identification of extremes is inappropriate if it is based on marginal analysis. Extremes have usually been linked to the notion of quantile, which is an important tool to analyze risk in the univariate setting. We propose to identify multivariate extremes and analyze environmental phenomena in terms of the directional multivariate quantile, which allows us to analyze the data considering all the variables implied in the phenomena, as well as look at the data in interesting directions that can better describe an environmental catastrophe. Since there are many references in the literature that propose extremes detection based on copula models, we also generalize the copula method by introducing the directional approach. Advantages and disadvantages of the non-parametric proposal that we introduce and the copula methods are provided in the paper. We show with simulated and real data sets how by considering the first principal component direction we can improve the visualization of extremes. Finally, two cases of study are analyzed: a synthetic case of flood risk at a dam (a 3-variable case), and a real case study of sea storms (a 5-variable case).
description: Article with supplementary material in the appendix
The disappearing middle : trends in the distribution of employment and income
Creators: name: Pang, Felicity.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Compressed quantum metrology for the Ising Hamiltonian
Creators: name: Boyajian, W. L.
name: Skotiniotis, M.
name: Dür, W.
name: Kraus, B.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show how quantum metrology protocols that seek to estimate the parameters of a Hamiltonian that exhibits a quantum phase transition can be efficiently simulated on an exponentially smaller quantum computer. Specifically, by exploiting the fact that the ground state of such a Hamiltonian changes drastically around its phase transition point, we construct a suitable observable from which one can estimate the relevant parameters of the Hamiltonian with Heisenberg scaling precision. We then show how, for the one-dimensional Ising Hamiltonian with transverse magnetic field acting on N spins, such a metrology protocol can be efficiently simulated on an exponentially smaller quantum computer while maintaining the same Heisenberg scaling, i.e., O(1/N^2) precision and derive the explicit circuit that accomplishes the simulation.
description: 11 pages, 4 figures
Key interactions of pyrimethamine derivatives specific to wild-type and mutant P. falciparum dihydrofolate reductase based on 3D-QSAR, MD simulations and quantum chemical calculations
Creators: name: Seetin, Sasipha
name: Saparpakorn, Patchreenart
name: Vanichtanankul, Jarunee
name: Vitsupakorn, Danoo
name: Yuthavong, Yongyuth
name: Kamchonwongpaisan, Sumalee
name: Hannongbua, Supa
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 60506
subject: Virology

description: Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) is an important target enzyme in malarial chemotherapy. An understanding of how novel inhibitors interact with wild-type (wtPfDHFR), quadruple-mutant (qmPfDHFR), and human (hDHFR) enzymes is required for the development of these compounds as antimalarials. This study is focused on a series of des-Cl and m-Cl phenyl analogs of pyrimethamine with various flexible 6-substituents. The interactions of these compounds with DHFR enzymes were investigated by 3 D-QSAR, MD simulations, MM-PBSA, and DFT calculations. CoMFA and CoMSIA models were developed with good predictive abilities for wtPfDHFR and qmPfDHFR. For hDHFR, CoMSIA models combined with clogP descriptor were successfully derived. Binding free energy using MM-PBSA and comparison of per residue decomposition energy analyses with the DFT method at M06-2X/6-31G ++(d,p) level of theory indicated that Asp54 and Phe58 play important roles in the binding of the most potent compound in the series (compound 27) with both wtPfDHFR and qmPfDHFR, whereas Arg59 and Arg122 were additionally found to interact with this inhibitor in qmPfDHFR. For hDHFR, the residues Glu30 and Phe34 but not Arg70, equivalent to Asp54, Phe58, and Arg122 in PfDHFR, also play role in compound 27 binding through strong hydrophobic interactions (Phe34) and hydrogen bond network with Glu30, Ile7, and Val115. From the key interactions identified in the DHFR-inhibitor complexes, a general scheme is proposed for designing new inhibitors selective for PfDHFR that is important for the development of novel antifolate antimalarials. Communicated by Ramaswamy H. Sarma
Many-body theory of positron binding in polyatomic molecules
Creators: name: Hofierka, J.
name: Cunningham, B.
name: Rawlins, C. M.
name: Patterson, C. H.
name: Green, D. G.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: Computational Physics (physics.comp-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Positrons bind to molecules leading to vibrational excitation and spectacularly enhanced annihilation. Whilst positron binding energies have been measured via resonant annihilation spectra for $\sim$90 molecules in the past two decades, an accurate \emph{ab initio} theoretical description has remained elusive. Of the molecules studied experimentally, calculations exist for only 6, and for these, standard quantum chemistry approaches have proved severely deficient, agreeing with experiment to at best 25% accuracy for polar molecules, and failing to predict binding in nonpolar molecules. The mechanisms of binding are not understood. Here, we develop a many-body theory of positron-molecule interactions and uncover the role of strong many-body correlations including polarization of the electron cloud, screening of the positron-electron Coulomb interaction by molecular electrons, and crucially, the unique non-perturbative process of virtual-positronium formation (where a molecular electron temporarily tunnels to the positron): they dramatically enhance binding in polar molecules and enable binding in nonpolars. We also elucidate the role of individual molecular orbitals, highlighting the importance of electronic $π$ bonds. Overall, we calculate binding energies in agreement with experiment (to within 1% in cases), and we predict binding in formamide and nucleobases. As well as supporting resonant annihilation experiments and positron-based molecular spectroscopy, the approach can be extended to positron scattering and annihilation $γ$ spectra in molecules and condensed matter, to provide fundamental insight and predictive capability required to properly interpret materials science diagnostics, develop antimatter-based technologies (including positron traps, beams and positron emission tomography), and understand positrons in the galaxy.
description: Significantly updated: improved calculation now gives near-exact agreement with experiment for some molecules (within 1% in some cases); strength of correlation potential has been delineated; contribution of individual molecular orbitals (including pi-bonds) to binding and annihilation has been elucidated etc
Protocoles pour l'étude histologique de gonades de poissons marins
Sample collection protocol for maturity staging of marine fish through histology
Creators: name: Dubroca, Laurent
name: Elie, Nicolas
name: Kellner, Kristell
name: Le Meleder, Anna
name: Parrad, Sophie
name: Sauger, Carine
name: Villain-Naud, Nadège
Publisher: name: Ifremer
Year: 2023

description: This protocol was set up under the MATO project (MATurité Objective des poissons par histologie quantitative), as part of Carine Sauger’s PhD. The MATO project, financed by IFREMER (Institut Français de Recherche pour l'Exploitation de la Mer), aims at improving the evaluation of sexual maturity stages of exploited stock species using histology paired with a stereology reading process. The present document gathers protocols used in the study of marine female fish gonads as well as the study of the different cellular structures found in ovaries at the Port-en-Bessin IFREMER laboratory. Materials used here are not always the most optimal but favor a manual approach. Most of the histological methods found in this protocol are based on methods described by Gabe, or were modified so as to answer our queries from a fisheries point of view, from the collection of fresh samples to the staining and mounting of histological slides, including inclusion in paraffin.
description: Ce recueil de protocoles a été mis en place dans le cadre du projet MATO (MATurité Objective des poisons par histologie quantitative) et dans le cadre de la thèse de Carine Sauger. Le projet MATO financé par l’IFREMER (Institut Français de Recherche pour l’Exploitation de la Mer) a pour but d’améliorer la détermination de la maturité sexuelle chez certaines espèces en utilisant l’histologie couplé à la stéréologie. Ce présent document recueille les protocoles utilisés à la station IFREMER de Port-en-bessin pour l’étude de gonades femelles de poissons marins et des différentes structures cellulaires retrouvées dans les ovaires. Les protocoles présents détaillent les méthodes utilisées, de la récolte de l’échantillon frais jusqu’au montage de la lame histologique et sa coloration, en passant par l’inclusion dans la paraffine. Il a été mis en place de façon à favoriser une approche manuelle des méthodes d’histologie.
On the General Analytical Solution of the Kinematic Cosserat Equations
Creators: name: Michels, Dominik
name: Lyakhov, Dmitry
name: Gerdt, Vladimir
name: Hossain, Zahid
name: Riedel-Kruse, Ingmar
name: Weber, Andreas
Publisher: name: arXiv
Year: 2016
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: Based on a Lie symmetry analysis, we construct a closed form solution to the kinematic part of the (partial differential) Cosserat equations describing the mechanical behavior of elastic rods. The solution depends on two arbitrary analytical vector functions and is analytical everywhere except a certain domain of the independent variables in which one of the arbitrary vector functions satisfies a simple explicitly given algebraic relation. As our main theoretical result, in addition to the construction of the solution, we proof its generality. Based on this observation, a hybrid semi-analytical solver for highly viscous two-way coupled fluid-rod problems is developed which allows for the interactive high-fidelity simulations of flagellated microswimmers as a result of a substantial reduction of the numerical stiffness.
description: 14 pages, 3 figures
The Spectral Sharpness Angle of Gamma-ray Bursts
Creators: name: Yu, Hoi-Fung
name: van Eerten, Hendrik J.
name: Greiner, Jochen
name: Sari, Re'em
name: Bhat, P. Narayana
name: von Kienlin, Andreas
name: Paciesas, William S.
name: Preece, Robert D.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We explain the results of Yu et al. (2015b) of the novel sharpness angle measurement to a large number of spectra obtained from the Fermi gamma-ray burst monitor. The sharpness angle is compared to the values obtained from various representative emission models: blackbody, single-electron synchrotron, synchrotron emission from a Maxwellian or power-law electron distribution. It is found that more than 91% of the high temporally and spectrally resolved spectra are inconsistent with any kind of optically thin synchrotron emission model alone. It is also found that the limiting case, a single temperature Maxwellian synchrotron function, can only contribute up to 58+23 -18% of the peak flux. These results show that even the sharpest but non-realistic case, the single-electron synchrotron function, cannot explain a large fraction of the observed spectra. Since any combination of physically possible synchrotron spectra added together will always further broaden the spectrum, emission mechanisms other than optically thin synchrotron radiation are likely required in a full explanation of the spectral peaks or breaks of the GRB prompt emission phase.
description: 9 pages, 7 figures. Published in JASS as a proceeding of the 6th Fermi Asian Network Workshop (FAN6)
In vitro and in silico cytotoxic activities of triterpenoids from the leaves of Aralia dasyphylla Miq. and the assessment of their ADMET properties
Creators: name: Thu, Hien Nguyen Thi
name: Huong, Duyen Nguyen Huu
name: Dieu, Thuan Nguyen Thi
name: Ngoc, Hanh Tran Thi
name: Van, Huyen Pham
name: Ngoc, Anh Hoang Thi
name: Xuan, Ha Nguyen
name: Pham, Ngoc Khanh
name: Manh, Cuong Nguyen
name: Toan, Phan Nguyen Huu
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
classificationCode: 59999
subject: Environmental Sciences not elsewhere classified
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
subject: Ecology
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 80699
subject: Information Systems not elsewhere classified
subject: Cancer

description: From the methanol extract of the leaves of Aralia dasyphylla Miq. (Araliaceae), ten triterpenoids including five ursane-type triterpenoids, ursolic acid (1), 3-O-α-l-arabinopyranosyl ursolic acid (2), ursolic acid 28-O-β-D-glucopyranosyl ester (3), 3-O-[β-D-glucopyranosyl (l→3)]-α-L-arabinopyranosyl ursolic acid (4), and matesaponin 1 (5), and five oleanane-type triterpenoids, elatoside E (6), elatoside F (7), 3-O-[β-D-glucopyranosyl (l→3)]-α-L-arabinopyranosyl oleanolic acid (8), 3-O-α-L-arabinopyranosyl oleanolic acid (9) and oleanolic acid 28-O-β-D-glucopyranosyl ester (10) were isolated. Their structures were elucidated based on 1D-, 2D-NMR and ESI-MS spectra as well as by comparison with those reported in the literature. All isolated compounds were evaluated in vitro for their cytotoxic activities against three human cancer cell lines (HepG2, LU-1 and RD) and in silico by molecular docking studies on human glucose transporter 1 (hGLUT1) protein. The triterpenoids 2, 4, 6, 8 and 9 exhibited good growth inhibition of HepG2 and LU-1 cancer cell lines with IC50 values in the range 1.76 − 7.21 (μM). The oleanane type triterpenoid 8 was the highest cytotoxic compound to inhibit all the tested cancer cell lines with IC50 values of 2.73 ± 0.12, 1.76 ± 0.11, 2.63 ± 0.10 μM, respectively. The in silico molecular docking study results showed that compounds 4 and 6 had the highest binding affinity. Compounds 1–10 were evaluated for their in silico ADMET of absorption, distribution, metabolism, excretion and oral toxicity parameters. Compounds 6, 8, 9 and 10 from A. dasyphylla are potential hGLUT1 inhibitors and worth of further investigation for the prevention or treatment of diabetes and cancer. Communicated by Ramaswamy H. Sarma
Neutral Kaon Mixing Beyond the Standard Model with $n_f=2+1$ Chiral Fermions Part 1: Bare Matrix Elements and Physical Results
Creators: name: Garron, Nicolas
name: Hudspith, Renwick J.
name: Lytle, Andrew T.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We compute the hadronic matrix elements of the four-quark operators relevant for $K^0-{\bar K^0}$ mixing beyond the Standard Model. Our results are from lattice QCD simulations with $n_f=2+1$ flavours of domain-wall fermion, which exhibit continuum-like chiral-flavour symmetry. The simulations are performed at two different values of the lattice spacing ($a\sim0.08$ and $a\sim 0.11 \, \fm $) and with lightest unitary pion mass $\sim 300\, \MeV$. For the first time, the full set of relevant four-quark operators is renormalised non-perturbatively through RI-SMOM schemes; a detailed description of the renormalisation procedure is presented in a companion paper. We argue that the intermediate renormalisation scheme is responsible for the discrepancies found by different collaborations. We also study different normalisations and determine the matrix elements of the relevant four-quark operators with a precision of $\sim 5\%$ or better.
description: 38 pages
Testing the achievements of micro-credit in Bangladesh : the case of BRAC
Creators: name: Hoque, Md. Serajul.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
The 2015 Decay of the Black Hole X-ray Binary V404 Cygni: Robust Disk-Jet Coupling and a Sharp Transition into Quiescence
Creators: name: Plotkin, R. M.
name: Miller-Jones, J. C. A.
name: Gallo, E.
name: Jonker, P. G.
name: Homan, J.
name: Tomsick, J. A.
name: Kaaret, P.
name: Russell, D. M.
name: Heinz, S.
name: Hodges-Kluck, E. J.
name: Markoff, S.
name: Sivakoff, G. R.
name: Altamirano, D.
name: Neilsen, J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present simultaneous X-ray and radio observations of the black hole X-ray binary V404 Cygni at the end of its 2015 outburst. From 2015 July 11-August 5 we monitored V404 Cygni with Chandra, Swift, and NuSTAR in the X-ray, and with the Karl G. Jansky Very Large Array and the Very Long Baseline Array in the radio, spanning a range of luminosities that were poorly covered during its previous outburst in 1989 (our 2015 campaign covers 2e33
description: 24 pages, 11 figures, 5 tables. Accepted for publication in ApJ
On the Einstein-Podolsky-Rosen paradox using discrete time physics
Creators: name: Riek, Roland
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Einstein-Podolski-Rosen paradox highlights several strange properties of quantum mechanics including the super position of states, the non locality and its limitation to determine an experiment only statistically. Here, this well known paradox is revisited theoretically for a pair of spin 1/2 systems in a singlet state under the assumption that in classical physics time evolves in discrete time steps Deltat while in quantum mechanics the individual spin system(s) evolve(s) between the eigenstates harmonically with a period of 4 Deltat. It is further assumed that time is a single variable, that the quantum mechanics time evolution and the classical physics discrete time evolution are coherent to each other, and that the precision of the start of the experiment and of the measurement time point are much less than Deltat. Under these conditions, it is demonstrated for a spin 1/2 system that the fast oscillation between the eigen states spin up and spin down reproduces the expected outcome of a single measurement as well as ensemble measurements without the need of postulating a simultaneous superposition of the spin system in its quantum state. When this concept is applied to a spin 1/2 system pair in a singlet state it is shown that no entanglement between the two spins is necessary to describe the system resolving the Einstein-Podolski-Rosen paradox.
PITRM1 interaction studies with amyloidogenic nonapeptide mutants of familial Alzheimer’s disease
Creators: name: Alphonse, Carlton Ranjith Wilson
name: Kannan, Rajaretinam Rajesh
name: Nagarajan, Nagasundaram
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 80699
subject: Information Systems not elsewhere classified
subject: Developmental Biology

description: Amyloid β-protein (ABP) is found to be the major cause for the development of neurodegeneration which leads to Alzheimer’s. The Aβ nonapeptide segment, QKLVFFAED (amino acids 15–23) is the highly amyloidogenic central region of Aβ. Familial mutation in Aβ increases the aggregation property of the peptide compared to the Native (Wild) amyloid-beta (Aβ) and these mutations fall on the Aβ nonapeptide segment. The catalytic activity of pitrilysin metallopeptidase 1(PITRM1) with familial mutant Aβ (Flemish, Arctic, Dutch, Italian and Iowa) during interaction is examined using molecular dynamic simulation. The molecular dynamics simulation of PITRM1 and the Aβ nonapeptide segment showed similar RMSD with respect to stability. The active site amino acid (AA) H108, hydrophobic pocket AA residues L111, F123, F124, and L127 and the basic pocket AA residues R888 and H896 showed similar interactions with both wild and familial Aβ. The molecular level interaction between amyloid beta and PITRM1 were similar in the wild and familial mutants except for the Arctic mutant. The hydrophobic interaction was commonly observed between the S1 hydrophobic pocket and the LVFF region, the Arctic mutant showed less hydrogen bond formation consistently when compared to other complexes. This molecular information on catalytic activity suggests that modulating inactive PITRM1 or an increase in expression of PITRM1 can help in eliminating different kinds of familial mutant Aβ in neurodegenerative cells. Communicated by Ramaswamy H. Sarma
Biochemical characterization and structure-based in silico screening of potent inhibitor molecules against the 1 cys peroxiredoxin of bacterioferritin comigratory protein family from Candidatus Liberibacter asiaticus
Creators: name: Gupta, Deena Nath
name: Dalal, Vikram
name: Savita, Brajesh Kumar
name: Alam, Md Shahid
name: Singh, Anamika
name: Gubyad, Mrugendra
name: Ghosh, Dilip Kumar
name: Kumar, Pravindra
name: Sharma, Ashwani Kumar
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 80699
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology

description: Bacterioferritin comigratory protein family 1 Cys peroxiredoxin from Candidatus Liberibacter asiaticus (CLaBCP) is an important antioxidant defense protein that participates in the reduction of ROS, free radicals, and peroxides. In the present study, we report the biochemical studies and in silico screening of potent antibacterial molecules against CLaBCP. The CLaBCP showed enzymatic activity with the Km value 54.43, 94.34, 120.6 µM, and Vmax of 59.37, 69.37, 70.0 µM min−1 for H2O2, TBHP, CHP respectively. The residual peroxidase activity of CLaBCP was analyzed at different ranges of pH and temperatures. The CLaBCP showed structural changes and unfolding in the presence of its substrates and guanidinium chloride by CD and fluorescence. The structure-based drug design method was employed to screen and identify the more efficient molecule against CLaBCP. The validated CLaBCP model was used for the virtual screening of potent antibacterial molecules. The docking was performed at CLaBCP active site to evaluate the binding energy of the top five molecules (LAS 34150849, BDE 33184869, LAS 51497689, BDE 33672484, and LAS 34150966). All identified molecule has a higher binding affinity than adenanthin analyzed by molecular docking. Molecular dynamics studies such as RMSD, Rg, SASA, and PCA results showed that the CLaBCP inhibitor(s) complex is more stable than the CLaBCP-adenanthin complex. MMPBSA results suggested that the identified molecule could form a lower energy CLaBCP-inhibiter(s) complex than the CLaBCP-adenanthin complex. The screened molecules may pave the route for the development of potent antibacterial molecules against CLa. Communicated by Ramaswamy H. Sarma
An economic analysis of the primary prevention of NIDDM
Creators: name: Dalton, Andrew.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Spin excitations in hole-overdoped iron-based superconductors
Creators: name: Horigane, K.
name: Kihou, K.
name: Fujita, K.
name: Kajimoto, R.
name: Ikeuchi, K.
name: Ji, S.
name: Akimitsu, J.
name: Lee, C. H.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Understanding the overall features of magnetic excitation is essential for clarifying the mechanism of Cooper pair formation in iron-based superconductors. In particular, clarifying the relationship between magnetism and superconductivity is a central challenge because magnetism may play a key role in their exotic superconductivity. BaFe2As2 is one of ideal systems for such investigation because its superconductivity can be induced in several ways, allowing a comparative examination. Here we report a study on the spin fluctuations of the hole-overdoped iron-based superconductors Ba1-xKxFe2As2 (x = 0.5 and 1.0; Tc = 36 K and 3.4 K, respectively) over the entire Brillouin zone using inelastic neutron scattering. We find that their spin spectra consist of spin wave and chimney-like dispersions. The chimney-like dispersion can be attributed to the itinerant character of magnetism. The band width of the spin wave-like dispersion is almost constant from the non-doped to optimum-doped region, which is followed by a large reduction in the overdoped region. This suggests that the superconductivity is suppressed by the reduction of magnetic exchange couplings, indicating a strong relationship between magnetism and superconductivity in iron-based superconductors.
description: 16 pages, 4 figures
The $3d$-Electron Heisenberg Pyrochlore Mn$_2$Sb$_2$O$_7$
Creators: name: Peets, Darren C.
name: Sim, Hasung
name: Avdeev, Maxim
name: Park, Je-Geun
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In frustrated magnetic systems, geometric constraints or the competition amongst interactions introduce extremely high degeneracy and prevent the system from readily selecting a low-temperature ground state. The most frustrated known spin arrangement is on the pyrochlore lattice, but nearly all magnetic pyrochlores have unquenched orbital angular momentum, constraining the spin directions through spin-orbit coupling. Pyrochlore Mn$_2$Sb$_2$O$_7$ is an extremely rare Heisenberg pyrochlore system, with directionally-unconstrained spins and low chemical disorder. We show that it undergoes a spin-glass transition at 5.5K, which is suppressed by disorder arising from Mn vacancies, indicating this ground state to be a direct consequence of the spins' interactions. The striking similarities to $3d$ transition metal pyrochlores with unquenched angular momentum suggests that the low spin-orbit coupling in the $3d$ block makes Heisenberg pyrochlores far more accessible than previously imagined.
description: 6 pages, 6 figues, including Supplementary
Novel 16-QAM and 64-QAM Near-Complementary Sequences with Low PMEPR in OFDM Systems
Creators: name: Jiang, Tao
name: Ni, Chunxing
name: Xu, Yuance
Publisher: name: arXiv
Year: 2016
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this paper, we firstly propose a novel construction of $16$-quadrature amplitude modulation (QAM) near-complementary sequences with low peak-to-mean envelope power ratio (PMEPR) in orthogonal frequency division multiplexing (OFDM) systems. The proposed $16$-QAM near-complementary sequences can be constructed by utilizing novel nonlinear offsets, where the length of the sequences is $n=2^m$. The family size of the newly constructed $16$-QAM near-complementary sequences is $8\times (\frac{m!}{2})\times 4^{m+1}$, and the PMEPR of these sequences is proven to satisfy ${\textrm{PMEPR}}\leq 2.4$. Thus, the proposed construction can generate a number of $16$-QAM near-complementary sequences with low PMEPR, resulting in the improvement of the code rate in OFDM systems. Furthermore, we also propose a novel construction of $64$-QAM near-complementary sequences with low PMEPR, which is the first proven construction of $64$-QAM near-complementary sequences. The PMEPRs of two types of the proposed $64$-QAM near-complementary sequences are proven to satisfy that ${\textrm{PMEPR}}\leq 3.62$ or ${\textrm{PMEPR}}\leq 2.48$, respectively. The family size of the newly constructed $64$-QAM near-complementary sequences is $64\times (\frac{m!}{2})\times 4^{m+1}$.
description: 27 pages, 2 figures, submitted to IEEE Transactions on Communications
title: Electromagnetic Interference Analysis of Fast-Switching-Speed Semiconductors Applied to Power Electronics Converters
Creators: name: Colvero Schittler, Andressa
Publisher: name: Universität Kassel
Year: 2023
Subjects: subject: EMC/EMI
subject: Passive filter
subject: High frequency power converter
subject: Wide bandgap devices
subject: Noise source
subject: 600
subject: Elektromagnetische Verträglichkeit
subject: Frequenzumrichter
subject: Hochfrequenz
subject: Lärm
subject: Halbleiter
subject: Interferenz

description: Zugleich: Universität Kassel, Dissertation, 2022
The near-infrared spectrum of ethynyl radical
Creators: name: Le, Anh T.
name: Hall, Gregory E.
name: Sears, Trevor J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Transient diode laser absorption spectroscopy has been used to measure three strong vibronic bands in the near infrared spectrum of the C$_2$H, ethynyl, radical not previously observed in the gas phase. The radical was produced by ultraviolet excimer laser photolysis of either acetylene or (1,1,1)-trifluoropropyne in a slowly flowing sample of the precursor diluted in inert gas, and the spectral resolution was Doppler-limited. The character of the upper states was determined from the rotational and fine structure in the observed spectra and assigned by measurement of ground state rotational combination differences. The upper states include a $^2Σ^+$ state at 6696 cm$^{-1}$, a second $^2Σ^+$ state at 7088 cm$^{-1}$, and a $^2Π$ state at 7110 cm$^{-1}$. By comparison with published calculations (R. Tarroni and S. Carter, \textit{J. Chem. Phys} \textbf{119}, 12878 (2003) and \textit{Mol. Phys}. \textbf{102}, 2167 (2004)), the vibronic character of these levels was also assigned. The observed states contain both $X^2Σ^+$ and $A^2Π$ electronic character. Several local rotational level perturbations were observed in the excited states. Kinetic measurements of the time-evolution of the ground state populations following collisional relaxation and reactive loss of the radicals formed in a hot, non-thermal, population distribution were made using some of the strong rotational lines observed. The case of C$ _{2} $H may be a good place to investigate the behavior at intermediate pressures of inert colliders, where the competition between relaxation and reaction can be tuned and observed to compare with master equation models, rather than deliberately suppressed to measure thermal rate constants.
description: 21 pages of text and references, 8 figures, 4 tables
Cosmogenic photons strongly constrain UHECR source models
Creators: name: van Vliet, Arjen
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: With the newest version of our Monte Carlo code for ultra-high-energy cosmic ray (UHECR) propagation, CRPropa 3, the flux of neutrinos and photons due to interactions of UHECRs with extragalactic background light can be predicted. Together with the recently updated data for the isotropic diffuse gamma-ray background (IGRB) by Fermi LAT, it is now possible to severely constrain UHECR source models. The evolution of the UHECR sources especially plays an important role in the determination of the expected secondary photon spectrum. Pure proton UHECR models are already strongly constrained, primarily by the highest energy bins of Fermi LAT's IGRB, as long as their number density is not strongly peaked at recent times.
description: 4 pages, 6 figures, submitted to the Proceedings of the ARENA-2016 conference (Groningen, the Netherlands, June 7 - 10th 2016)
Testing the efficient market hypothesis in an autocratic political economy
Creators: name: Duke, Charlotte.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Affinity variation in the interactions of tryptophan- β-cyclodextrin-platinum complex with G-quadruplex and duplex DNAs
Creators: name: Muruganantham, Aishwarya
name: Sahayam, Arokya Nithya Deva
name: Suganthi, Soundarapandian
name: Alexander, Aleyamma
name: Pillai, Archana Sumohan
name: Enoch, Israel V. M. V.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
classificationCode: 39999
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: DNA forms non-canonical Guanine-rich-quadruplex structures that play crucial roles such as maintenance of the telomere, transcription, and replication. Selective binding of small molecular ligands to G-quadruplexes and stabilization of them gain importance in the control of cell proliferation and development of therapeutics. In this paper, we report the synthesis of a tryptophan-β-cyclodextrin complex and its platinum complex. The binding interaction of the synthesized Trp-β-CD-Pt compound with various DNAs, including a duplex DNA and three quadruplexes, are investigated. The binding of the compound to quadruplexes shows a general increase in the binding strength compared to the strength of binding with the duplex, CT-DNA. The compound reveals the strongest binding with kit22. An enhancement of fluorescence is generally observed when the ligand binds to all the DNAs, except myc22. The structure of the host: guest complex with Berberine, a model G-quadruplex binding ligand, is investigated using 2 D ROESY spectroscopy. The host: guest binding is strong and the DNA interaction does not extract much of the Berberine molecule from the complex. The differential bindings of the ligand in free- and Berberine-loaded forms with different G-quadruplexes are discussed in detail based on binding strengths and the modulation of fluorescence. Communicated by Ramaswamy H. Sarma
Secrecy and Energy Efficiency in Massive MIMO Aided Heterogeneous C-RAN: A New Look at Interference
Creators: name: Wang, Lifeng
name: Wong, Kai-Kit
name: Elkashlan, Maged
name: Nallanathan, Arumugam
name: Lambotharan, Sangarapillai
Publisher: name: arXiv
Year: 2016
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: In this paper, we investigate the potential benefits of the massive multiple-input multiple-output (MIMO) enabled heterogeneous cloud radio access network (C-RAN) in terms of the secrecy and energy efficiency (EE). In this network, both remote radio heads (RRHs) and massive MIMO macrocell base stations (BSs) are deployed and soft fractional frequency reuse (S-FFR) is adopted to mitigate the inter-tier interference. We first examine the physical layer security by deriving the area ergodic secrecy rate and secrecy outage probability. Our results reveal that the use of massive MIMO and C-RAN can greatly improve the secrecy performance. For C-RAN, a large number of RRHs achieves high area ergodic secrecy rate and low secrecy outage probability, due to its powerful interference management. We find that for massive MIMO aided macrocells, having more antennas and serving more users improves secrecy performance. Then we derive the EE of the heterogeneous C-RAN, illustrating that increasing the number of RRHs significantly enhances the network EE. Furthermore, it is indicated that allocating more radio resources to the RRHs can linearly increase the EE of RRH tier and improve the network EE without affecting the EE of the macrocells.
description: 26 pages, 11 figures, to appear in IEEE Journal of Selected Topics in Signal Processing