cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Kähler-Ricci flow on non-compact manifolds
Creators: name: Li, Ka-Fai
Publisher: name: University of British Columbia
Year: 2018

description: We first study the general theory of Kähler-Ricci flow on non-compact complex manifolds. By using a parabolic Schwarz lemma and a local scalar curvature estimate, we prove a general existence theorem for Kähler metrics lying in the C^\infty _\loc closure of complete bounded curvature Kähler metrics that are uniformly equivalent to a fixed background metric. In particular we do not assume any curvature bounds. Next, we compare the maximal existence time of two complete bounded curvature solutions by using the equivalence of the initial metrics and using this, we also estimate the maximal existence time of a complete bounded curvature solution in terms of the curvature bound of a background metric. We also prove a uniqueness theorem for Kähler-Ricci flow which slightly improves the result of [13] in the Kähler case. We apply the above results to study the Kähler-Ricci flow on some specific non-compact complex manifolds. We first study the Kähler-Ricci flow on C^n. By applying our general existence theorem and existence time estimate, we show that any complete non-negatively curved U(n)-invariant Kähler metric admits a longtime U(n)-invariant solution to the Kähler-Ricci flow, and the solution converges to the standard Euclidean metric after rescaling. Then we study the Kähler-Ricci flow on a quasi-projective manifold. By modifying the approximation theorem of [1] and applying a general existence theorem of Lott-Zhang [23], we construct a Kähler-Ricci flow solution starting from certain smooth Kähler metrics. In particular, if the metric is the restriction of a smooth Kähler metric in the ambient space, then the solution instantaneously becomes complete and has cusp singularity at the divisor. We also produce a solution starting from some complete metrics that may not have bounded curvature, and the solution is likewise complete with cusp singularity for positive time. On the other hand, if the initial data has bounded curvature and is asymptotic to the standard cusp model in a certain sense, we find the maximal existence time of the corresponding complete bounded curvature solution to the Kähler-Ricci flow.
In silico analysis and identification of promising hits against 2019 novel coronavirus 3C-like main protease enzyme
Creators: name: Chatterjee, Shilpa
name: Maity, Arindam
name: Chowdhury, Suchana
name: Islam, Md Ataul
name: Muttinini, Ravi K.
name: Sen, Debanjan
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: The recent outbreak of the 2019 novel coronavirus disease (COVID-19) has been proved as a global threat. No particular drug or vaccine has not yet been discovered which may act specifically against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and causes COVID-19. For this highly infectious virus, 3CL-like main protease (3CLpro) plays a key role in the virus life cycle and can be considered as a pivotal drug target. Structure-based virtual screening of DrugBank database resulted in 20 hits against 3CLpro. Atomistic 100 ns molecular dynamics of five top hits and binding energy calculation analyses were performed for main protease-hit complexes. Among the top five hits, Nafarelin and Icatibant affirmed the binding energy (g_MMPBSA) of –712.94 kJ/mol and –851.74 kJ/mol, respectively. Based on binding energy and stability of protein-ligand complex; the present work reports these two drug-like hits against SARS-CoV-2 main protease. Communicated by Ramaswamy H. Sarma
Some comments on pinwheel tilings and their diffraction
Creators: name: Grimm, Uwe
name: Deng, Xinghua
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 52C23

description: The pinwheel tiling is the paradigm for a substitution tiling with circular symmetry, in the sense that the corresponding autocorrelation is circularly symmetric. As a consequence, its diffraction measure is also circularly symmetric, so the pinwheel diffraction consists of sharp rings and, possibly, a continuous component with circular symmetry. We consider some combinatorial properties of the tiles and their orientations, and a numerical approach to the diffraction of weighted pinwheel point sets.
description: 9 pages, 9 figures
Flavor from M5-branes
Creators: name: Fiol, Bartomeu
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study various aspects of the defect conformal field theory that arises when placing a single M5-brane probe in AdS_4 x S^7. We derive the full set of fluctuation modes and dimensions of the corresponding dual operators. We argue that the latter does not depend on the presence of a non-trivial magnetic flux on the M5-brane world-volume. Finally we give a mass to the hypermultiplet living on the defect, and compute the resulting mesonic spectrum.
description: 19 pages
HST Paschen-alpha Survey of the Galactic Center: Data Reduction and Products
Creators: name: Dong, H.
name: Wang, Q. D.
name: Cotera, A.
name: Stolovy, S.
name: Morris, M. R.
name: Mauerhan, J.
name: Mills, E. A.
name: Schneider, G.
name: Calzetti, D.
name: Lang, C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Our HST/NICMOS Pa survey of the Galactic center (GC) provides a uniform, panoramic, high-resolution map of stars and ionized diffuse gas in the central 416 arcmin^2 of the Galaxy. This survey was carried out with 144 HST orbits using two narrow-band filters at 1.87 and 1.90 micron in NICMOS Camera 3. In this paper, we describe in detail the data reduction and mosaicking procedures followed, including background level matching and astrometric corrections. We have detected ~570,000 near-IR sources and are able to quantify photometric uncertainties of the detections. The source detection limit varies across the survey field but the typical 50% completion limit is ~17th mag (Vega System) in the 1.90 micron band. A comparison with the expected stellar magnitude distribution shows that these sources are primarily Main-Sequence massive stars (>7M) and evolved lower mass stars at the distance of the GC. In particular, the observed source magnitude distribution exhibits a prominent peak, which could represent the Red Clump stars within the GC. The observed magnitude and color of these RC stars support a steep extinction curve in the near-IR toward the GC. The flux ratios of our detected sources in the two bands also allow for an adaptive and statistical estimate of extinction across the field. With the subtraction of the extinction-corrected continuum, we construct a net Pa emission map and identify a set of Pa-emitting sources, which should mostly be evolved massive stars with strong stellar winds. The majority of the identified Pa point sources are located within the three known massive GC stellar clusters. However, a significant fraction of our Pa-emitting sources are located outside the clusters and may represent a new class of `field' massive stars, many of which may have formed in isolation and/or in small groups. The maps and source catalogues presented here are available electronically.
description: Accepted for publication in MNRAS
Appendix S1 from Captive-bred populations of a partially migratory salmonid fish are unlikely to maintain migratory polymorphism in natural habitats
Creators: name: Tanaka, Tatsuya
name: Ueda, Rui
name: Sato, Takuya
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Additional details for age at migration of red-spotted masu salmon Oncorhynchus masou ishikawae, field and mesocosm experiments, and the proportion of precocious male.
Additional file 1 of Longitudinal associations between infant movement behaviours and development
Creators: name: Carson, Valerie
name: Zhang, Zhiguang
name: Predy, Madison
name: Pritchard, Lesley
name: Hesketh, Kylie D.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1 Supplementary Table 1. Spearman’s rank correlations between questionnaire and time-use diary measures of movement behaviours across three time points. Supplementary Table 2. Longitudinal associations between average movement behaviours across the three time points and exact milestone age outcomes.
Open Access in den Schweizer Rechtswissenschaften
Creators: name: Immenhauser, Beat
Publisher: name: Zenodo
Year: 2019
Subjects: Open Access
Rechtswissenschaften

description: Erste Präsentation anlässlich des DekanInnen-Tags 2019 am 5. April über die Situation des Open Access in den Rechtswissenschaften. Neue Fassung der Präsentation anlässlich der Table Ronde Open Access in den Schweizer Rechtswissenschaften am 27.11.2019 bei der SAGW.
description: cite as: Beat Immenhauser (2019): Open Access in den Schweizer Rechtswissenschaften. Präsentation 2019-11-27. zenodo. https://doi.org/10.5281/zenodo.2605053
Strong approximation of fractional Brownian motion by moving averages of simple random walks
Creators: name: Szabados, Tamas
Publisher: name: arXiv
Year: 2010
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: Primary 60G18, 60F15. Secondary 60J65

description: The fractional Brownian motion is a generalization of ordinary Brownian motion, used particularly when long-range dependence is required. Its explicit introduction is due to B.B. Mandelbrot and J.W. van Ness (1968) as a self-similar Gaussian process $\WH (t)$ with stationary increments. Here self-similarity means that $(a^{-H}\WH(at): t \ge 0) \stackrel{d}{=} (\WH(t): t \ge 0)$, where $H\in (0, 1)$ is the Hurst parameter of fractional Brownian motion. F.B. Knight gave a construction of ordinary Brownian motion as a limit of simple random walks in 1961. Later his method was simplified by P. Révész (1990) and then by the present author (1996). This approach is quite natural and elementary, and as such, can be extended to more general situations. Based on this, here we use moving averages of a suitable nested sequence of simple random walks that almost surely uniformly converge to fractional Brownian motion on compacts when $H \in (\quart , 1)$. The rate of convergence proved in this case is $O(N^{-\min(H-\quart,\quart)}\log N)$, where $N$ is the number of steps used for the approximation. If the more accurate (but also more intricate) Komlós, Major, Tusnády (1975, 1976) approximation is used instead to embed random walks into ordinary Brownian motion, then the same type of moving averages almost surely uniformly converge to fractional Brownian motion on compacts for any $H \in (0, 1)$. Moreover, the convergence rate is conjectured to be the best possible $O(N^{-H}\log N)$, though only $O(N^{-\min(H,\half)}\log N)$ is proved here.
description: 30 pages, 4 figures
Open Access in den Schweizer Rechtswissenschaften
Creators: name: Immenhauser, Beat
Publisher: name: Zenodo
Year: 2019
Subjects: Open Access
Rechtswissenschaften

description: Präsentation anlässlich des DekanInnen-Tags 2019 am 5. April über die Situation des Open Access in den Rechtswissenschaften.
description: cite as: Beat Immenhauser (2019): Open Access in den Schweizer Rechtswissenschaften. Präsentation. zenodo. https://doi.org/10.5281/zenodo.2605053
Climate change litigation and corporate accountability in Nigeria : the pathway to climate justice?
Creators: name: Duruike, Princess
Publisher: name: University of British Columbia
Year: 2018

description: Oil and gas is the linchpin of the Nigerian economy. However, oil exploration and exploitation processes of petroleum products, particularly in the Niger Delta, have generated unpleasant social and environmental challenges ranging from oil spill, gas flaring and discharge of waste and effluents which have wreaked havoc on the health of the Niger Delta people and the ecosystems upon which they depend. This thesis is particularly concerned with gas flaring: the burning of associated natural gas found with oil deposits. Nigeria is currently ranked as the world’s fifth-largest gas flaring country in the world. This wasteful practice of burning non-renewable energy results in the release of greenhouse gases into the atmosphere which cause extreme climatic changes. Climate change is said to be the current greatest environmental and social threat to sustainable development. Although no region of the world will be entirely spared, scientific research has shown that there are uneven effects of these challenges and vulnerabilities to these challenges across world territories. Some continents, more than others, are vulnerable to the catastrophic effects of climate change. For instance, it is feared that African countries like Nigeria might experience the most severe impacts of climate change compared to other continents in the world and they are the least prepared to handle these impacts as a result of poverty and low technological development. Litigation has been heralded as a promising, effective, and alternative path to encourage climate change mitigation and victim compensation. This thesis analyzes the core assumptions that guide current scholarly enthusiasm for the capacity of climate change litigation to reduce environmental harm based on the experiences in the United States of America and Australia and contrasts that with the unique contextual factors that have impeded the overarching success of climate change litigation in Nigeria. The current state of climate change litigation in Nigeria reveals the lack of political will to enforce the court’s judgment because of the economic importance of the Oil and Gas Industry, lack of judicial independence, the lack of gas conservation infrastructure and the Joint Venture arrangement between the state and the Transnational oil companies.
Screening of Chloroquine, Hydroxychloroquine and its derivatives for their binding affinity to multiple SARS-CoV-2 protein drug targets
Creators: name: Nimgampalle, Mallikarjuna
name: Devanathan, Vasudharani
name: Saxena, Ambrish
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Recently Chloroquine and its derivative Hydroxychloroquine have garnered enormous interest amongst the clinicians and health authorities’ world over as a potential treatment to contain COVID-19 pandemic. The present research aims at investigating the therapeutic potential of Chloroquine and its potent derivative Hydroxychloroquine against SARS-CoV-2 viral proteins. At the same time screening was performed for some chemically synthesized derivatives of Chloroquine and compared their binding efficacy with chemically synthesized Chloroquine derivatives through in silico approaches. For the purpose of the study, some essential viral proteins and enzymes were selected that are implicated in SARS-CoV-2 replication and multiplication as putative drug targets. Chloroquine, Hydroxychloroquine, and some of their chemically synthesized derivatives, taken from earlier published studies were selected as drug molecules. We have conducted molecular docking and related studies between Chloroquine and its derivatives and SARS-CoV-2 viral proteins, and the findings show that both Chloroquine and Hydroxychloroquine can bind to specific structural and non-structural proteins implicated in the pathogenesis of SARS-CoV-2 infection with different efficiencies. Our current study also shows that some of the chemically synthesized Chloroquine derivatives can also potentially inhibit various SARS-CoV-2 viral proteins by binding to them and concomitantly effectively disrupting the active site of these proteins. These findings bring into light another possible mechanism of action of Chloroquine and Hydroxychloroquine and also pave the way for further drug repurposing and remodeling. Communicated by Ramaswamy H. Sarma
[Two leaves from the St. Alban's Bible: Samuel and Genesis]
Creators: name: (:Null)
Publisher: name: [Paris] : [Publisher not identified]
Year: 2019

description: Two leaves from the St Albans Bible, an early-fourteenth century bible produced by artisans in the Paris book trade.
The text is copied in a medium-quality littera textualis. This leaf contains decorated borders, running titles, and initials, for which gold leaf was used, as well as yellow wash in the capital letters.
Data Management Plans: a Data Steward/Researcher Perspective
Creators: name: Plomp, Esther
Publisher: name: Zenodo
Year: 2019
Subjects: Data Stewards
TU Delft
DMPonline
Data Management Plans
DMP

description: Presentation for the DTL Data Stewards Interest Group on the 22nd of March 2019 by Esther Plomp on behalf of the Data Steward team at TU Delft. The presentation outlines the Data Stewardship programme at TU Delft, the support available for writing data management plans (DMP) and gives an overview of the feedback from TU Delft researchers on this support, as well as the DMPonline tool. A shortened version of the draft version of the TU Delft DMP template is included at the end of the presentation.
SoCov: Semi-Orthogonal Parametric Pooling of Covariance Matrix for Speaker Recognition
Creators: name: Li, Rongjin
name: Zhang, Weibin
name: Chen, Dongpeng
name: Kang, Jintao
name: Xing, Xiaofen
Publisher: name: arXiv
Year: 2025
Subjects: subject: Audio and Speech Processing (eess.AS)
subject: Sound (cs.SD)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: In conventional deep speaker embedding frameworks, the pooling layer aggregates all frame-level features over time and computes their mean and standard deviation statistics as inputs to subsequent segment-level layers. Such statistics pooling strategy produces fixed-length representations from variable-length speech segments. However, this method treats different frame-level features equally and discards covariance information. In this paper, we propose the Semi-orthogonal parameter pooling of Covariance matrix (SoCov) method. The SoCov pooling computes the covariance matrix from the self-attentive frame-level features and compresses it into a vector using the semi-orthogonal parametric vectorization, which is then concatenated with the weighted standard deviation vector to form inputs to the segment-level layers. Deep embedding based on SoCov is called ``sc-vector''. The proposed sc-vector is compared to several different baselines on the SRE21 development and evaluation sets. The sc-vector system significantly outperforms the conventional x-vector system, with a relative reduction in EER of 15.5% on SRE21Eval. When using self-attentive deep feature, SoCov helps to reduce EER on SRE21Eval by about 30.9% relatively to the conventional ``mean + standard deviation'' statistics.
description: This paper has been accepted by IEEE ICASSP2025
In-silico investigation of phytochemicals from Asparagus racemosus as plausible antiviral agent in COVID-19
Creators: name: Chikhale, Rupesh V.
name: Sinha, Saurabh K.
name: Patil, Rajesh B.
name: Prasad, Satyendra K.
name: Shakya, Anshul
name: Gurav, Nilambari
name: Prasad, Rupali
name: Dhaswadikar, Suhas R.
name: Wanjari, Manish
name: Gurav, Shailendra S.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: COVID-19 has ravaged the world and is the greatest of pandemics in human history, in the absence of treatment or vaccine the mortality and morbidity rates are very high. The present investigation was undertaken to screen and identify the potent leads from the Indian Ayurvedic herb, Asparagus racemosus (Willd.) against SARS-CoV-2 using molecular docking and dynamics studies. The docking analysis was performed on the Glide module of Schrödinger suite on two different proteins from SARS-CoV-2 viz. NSP15 Endoribonuclease and spike receptor-binding domain. Asparoside-C, Asparoside-D and Asparoside -F were found to be most effective against both the proteins as confirmed through their docking score and affinity. Further, the 100 ns molecular dynamics study also confirmed the potential of these compounds from reasonably lower root mean square deviations and better stabilization of Asparoside-C and Asparoside-F in spike receptor-binding domain and NSP15 Endoribonuclease respectively. MM-GBSA based binding free energy calculations also suggest the most favourable binding affinities of Asparoside-C and Asparoside-F with binding energies of −62.61 and −55.19 Kcal/mol respectively with spike receptor-binding domain and NSP15 Endoribonuclease. HighlightsAsparagus racemosus have antiviral potentialPhytochemicals of Shatavari showed promising in-silico docking and MD resultsAsparaoside-C and Asparoside-F has good binding with target proteinsAsparagus racemosus holds promise as SARS-COV-2 (S) and (N) proteins inhibitor Asparagus racemosus have antiviral potential Phytochemicals of Shatavari showed promising in-silico docking and MD results Asparaoside-C and Asparoside-F has good binding with target proteins Asparagus racemosus holds promise as SARS-COV-2 (S) and (N) proteins inhibitor Communicated by Ramaswamy H. Sarma
title: Studien zu den die unfigürlichen Stukkaturen des frühmittelalterlichen Klosters Disentis. Die Funde der Grabungen von 1891-1934
title: Magisterarbeit, Universität Freiburg i. Br. 1990
titleType: Subtitle
Creators: name: Weyer, Angela
Publisher: name: Hornemann Institut
Year: 2020
Subjects: Art history

description: Die im Kloster Disentis (CH) aufbewahrten Stuckfragmente bilden den größten und bedeutendsten bis heute bekannten Bestand architekturgebundener karolingischer Stuckplastik. Die Stuckaturen bestehen aus Kalkmörtel sind überwiegend frei angetragen, viele mit gut erhaltener Secco-Malerei gefasst, und – sieht man von ihrer Fragmentierung ab – bis auf wenige Ausnahmen nahezu unverändert erhalten geblieben. Sie kamen zusammen mit Resten eines Mosaikfußbodens und Wandmalerei bei Grabungen zwischen 1891 und 1934 zu Tage, nur wenige waren 1989 zusammengesetzt, nur ein kleiner Teil veröffentlicht. Von den ca. 3700 überlieferten, größtenteils farbig gefassten Stücken werden in dieser Magisterarbeit erstmalig die ca. 1200 unfigürlichen, sparsam gefassten Fragmente mit allen, sehr unterschiedlichen Werksspuren beschrieben, photographisch und zeichnerisch der Hauptteil 1:1 dokumentiert, in idealisierte Rekonstruktionszeichnungen integriert, der eigentümliche Motivschatz in das zeitlich und örtlich naheliegende Ornamentrepertoire kunsthistorisch eingeordnet. Durch die intensive Analyse aller Objekte wurde nicht nur der bisher bekannte Ornamentschatz deutlich ausgeweitet, sondern die vorgefundene grobe Ordnung der unfigürlichen Stuckplastik deutlich differenziert. Schließlich konnten 16 verschieden große Bögen, 8 Friesornamente, 4 Flächenornamente sowie über 20 Kapitelle über gedrehten oder glatten, halb- und dreiviertelkreisförmigen Säulenschäften und 2 verschiedene Krabbenbekrönungen rekonstruiert werden. Die vielen dokumentierten Vorritzungs- und Vorzeichnungsspuren führten zudem zu neuen Überlegungen zum Werkprozess in der Karolingerzeit. Eine kleine Essenz der Arbeit wurde bereits 1999 in der Zeitschrift für Schweizerische Archäologie und Kunstgeschichte 49, Heft 4, veröffentlicht. Der themenreiche Volltext und der umfangreiche Katalog aller Stücke lagen seit Fertigstellung sowohl im Kloster wie auch in der Eidgenössischen Kommission für Denkmalpflege vor und werden nun hier der weltweiten Forschungscommunity zur Verfügung gestellt, weil diese Detailkenntnisse für viele Themenkomplexe bedeutend sind. Schlagworte: Disentis, Stukkaturen, Stuck, Architekturgliederung, Kalkstuck, Bögen, Friese, Frühmittelalter, secco Malerei, Wandgliederung, Antragstechnik
Activation of the Calcium-Sensing Receptor by Glutathione Maillard Products: Implications for Kokumi Sensation
Creators: name: Ahmad, Raise
name: Deb Choudhury, Santanu
name: Subbaraj, Arvind
name: Kim, Jihan
Publisher: name: AgResearch
Year: 2025
Subjects: classificationCode: 3006
subject: Food sciences

description: Kokumi peptides, like glutathione (GSH), activate the calcium-sensing receptor (CaSR) in taste buds, contributing to kokumi sensory attributes. The CaSR assay is a reliable screening tool for kokumi compounds. Foods with GSH Maillard reaction products (GMRPs) show altered aromatic compounds and enhanced kokumi characteristics. However, limited evidence exists on whether GMRPs activate CaSR. This study examined the effect of glutathione thermal treatment and Maillard reaction with glucose and xylose at 80°C, 120°C, and 150°C on in vitro CaSR activity. We also quantified volatile compounds to understand changes during thermal and Maillard processes. GSH showed reduced CaSR activity at higher temperatures, which was restored and increased with glucose at 150°C. While xylose had no effect on CaSR activity, the Maillard reaction altered volatile compounds profile. Our findings suggest that GMRPs with glucose at elevated temperatures may act as positive allosteric modulators of CaSR, enhancing intracellular calcium levels.Preprint posted on SSRN
Universal features in sequential and nonsequential two-photon double ionization of helium
Creators: name: Pazourek, R.
name: Feist, J.
name: Nagele, S.
name: Persson, E.
name: Schneider, B. I.
name: Collins, L. A.
name: Burgörfer, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We analyze two-photon double ionization of helium in both the nonsequential and sequential regime. We show that the energy spacing between the two emitted electrons provides the key parameter that controls both the energy and the angular distribution and reveals the universal features present in both the nonsequential and sequential regime. This universality, i.e., independence of photon energy, is a manifestation of the continuity across the threshold for sequential double ionization. For all photon energies, the energy distribution can be described by a universal shape function that contains only the spectral and temporal information entering second-order time-dependent perturbation theory. Angular correlations and distributions are found to be more sensitive to the photon energy. In particular, shake-up interferences have a large effect on the angular distribution. Energy spectra, angular distributions parameterized by the anisotropy parameters, and total cross sections presented in this paper are obtained by fully correlated time-dependent ab initio calculations.
description: 12 pages, 8 figures
Additional file 1 of First-in-human autologous oral mucosal epithelial sheet transplantation to prevent anastomotic re-stenosis in congenital esophageal atresia
Creators: name: Fujino, Akihiro
name: Fuchimoto, Yasushi
name: Baba, Yoshiyuki
name: Isogawa, Nobutaka
name: Iwata, Takanori
name: Arai, Katsuhiro
name: Abe, Makoto
name: Kanai, Nobuo
name: Takagi, Ryo
name: Maeda, Masanori
name: Umezawa, Akihiro
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 60506 Virology

description: Additional file 1: Table S1. Inspection items for epithelial cell sheet transplantation and their timing
Monk's Tale: The Presidential Years, 1987-2005
Creators: name: Malloy, C.S.C., Edward A.
Publisher: name: University of Notre Dame
Year: 2023

description: This long-awaited, last installment of Reverend Edward A. Malloy's three-volume memoir examines his eighteen years as president of the University of Notre Dame from 1987 to 2005. In this candid and lively account, Malloy, or 'Monk' to all who know him, shares his reflections on his presidency following the long-term leadership of Theodore M. Hesburgh, C.S.C. Malloy describes his transition into the presidency, his approach to leadership, issues related to Catholic identity, the importance of fund-raising, and finding the proper balance in intercollegiate athletics. Communication issues were of paramount importance during Malloy's tenure, and he discusses how he fostered good relationships with the surrounding community, and supported trustees, administration, faculty, and other important constituencies in the governance of the university. An inveterate multitasker, he also examines how he organized his office and schedule, worked with administrative associates, handled a busy domestic and international travel schedule, sustained his participation in numerous external boards, and kept in regular contact with alumni and friends of the university. Finally, he looks at controversial issues, providing an insider's account of various challenges and crises, from personnel problems to NCAA sanctions to concerns about presidential succession. During nearly two decades, Father Malloy met with presidents and movie stars, sports legends, benefactors, and university employees, many of whom are mentioned in this book. Throughout this volume, Malloy's love for Notre Dame and its students, faculty, and staff comes through clearly, along with his overwhelming sense of gratitude for the opportunity to lead a university where faith, community, and service are taken seriously and passed on from one generation to the next.\u000a\u000a\u00A9 University of Notre Dame\u000a\u000aCopyright for most content is held by The University of Notre Dame. Reproduction of all or any portion of content constitutes a violation of copyright. You must obtain permission from The Copyright Clearance Center or The University of Notre Dame Press in order to reprint (or adapt) content.\u000a\u000ap: (574) 631-6346 \ e: undpress@nd\.edu \ website: copyright\.com
Angular momentum sum rule in nuclei
Creators: name: Taneja, Swadhin K.
name: Liuti, Simonetta
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this work we derive a sum rule for the angular momentum of a spin 1 hadronic system.
description: 5 pages, to appear in Proceedings of XVIII International Workshop on Deep-Inelastic Scattering and Related Subjects, April 19 -23, 2010, Convitto della Calza, Firenze, Italy
Magnetic Domains in Magnetar Matter as an Engine for Soft Gamma-ray Repeaters and Anomalous X-ray Pulsars
Creators: name: Suh, In-Saeng
name: Mathews, Grant J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Magnetars have been suggested as the most promising site for the origin of observed soft gamma-ray repeaters (SGRs) and anomalous X-ray pulsars (AXPs). In this work we investigate the possibility that SGRs and AXPs might be observational evidence for a magnetic phase separation in magnetars. We study magnetic domain formation as a new mechanism for SGRs and AXPs in which magnetar-matter separates into two phases containing different flux densities. We identify the parameter space in matter density and magnetic field strength at which there is an instability for magnetic domain formation. We conclude that such instabilities will likely occur in the deep outer crust for the magnetic Baym, Pethick, and Sutherland (BPS) model and in the inner crust and core for magnetars described in relativistic Hartree theory. Moreover, we estimate that the energy released by the onset of this instability is comparable with the energy emitted by SGRs.
description: 4 figures, ApJ in press
Additional file 1 of It is not a big deal: a qualitative study of clinical biobank donation experience and motives
Creators: name: Antonova, Natalia
name: Eritsyan, Ksenia
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: The interview guides.
Изменения названий городов и райцентров Азербайджана в течении ХХ в. как индикатор масштабов трансформации социально-культурной среды
Creators: name: А.Н., Ямсков
Publisher: name: Zenodo
Year: 2020
Subjects: Азербайджан
топонимия
территориальная идентичность
изменения ойконимов

description: Рассматривая ойконимию как важнейший маркер социально-культурной среды, автор предлагает классификацию всего спектра изменений соответствующей топонимии и связанной с ней территориальной идентичности населения на примере Азербайджана, с параллелями в других государствах Закавказья.
Fermi Observations of GRB 090510: A Short Hard Gamma-Ray Burst with an Additional, Hard Power-Law Component from 10 keV to GeV Energies
Creators: name: LAT, The Fermi
name: Collaborations, GBM
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present detailed observations of the bright short-hard gamma-ray burst GRB 090510 made with the Gamma-ray Burst Monitor (GBM) and Large Area Telescope (LAT) on board the Fermi observatory. GRB 090510 is the first burst detected by the LAT that shows strong evidence for a deviation from a Band spectral fitting function during the prompt emission phase. The time-integrated spectrum is fit by the sum of a Band function with $\Epeak = 3.9\pm 0.3$\,MeV, which is the highest yet measured, and a hard power-law component with photon index $-1.62\pm 0.03$ that dominates the emission below $\approx$\,20\,keV and above $\approx$\,100\,MeV. The onset of the high-energy spectral component appears to be delayed by $\sim$\,0.1\,s with respect to the onset of a component well fit with a single Band function. A faint GBM pulse and a LAT photon are detected 0.5\,s before the main pulse. During the prompt phase, the LAT detected a photon with energy $30.5^{+5.8}_{-2.6}$ GeV, the highest ever measured from a short GRB. Observation of this photon sets a minimum bulk outflow Lorentz factor, $Γ\ga$\,1200, using simple $γγ$ opacity arguments for this GRB at redshift $z = 0.903$ and a variability time scale on the order of tens of ms for the $\approx$\,100\,keV--few MeV flux. Stricter high confidence estimates imply $Γ\ga 1000$ and still require that the outflows powering short GRBs are at least as highly relativistic as those of long duration GRBs. Implications of the temporal behavior and power-law shape of the additional component on synchrotron/synchrotron self-Compton (SSC), external-shock synchrotron, and hadronic models are considered.
description: 33 pages, 7 figures, Accepted for publication in ApJ. Contact Authors: James Chiang (jchiang@slac.stanford.edu), Jonathon Granot (j.granot@herts.ac.uk), Sylvain Guiriec (sylvain.guiriec@lpta.in2p3.fr), Masanori Ohno (ohno@astro.isas.jaxa.jp)
A mechanistic explanation of two novel Zn(II) dithiocarbamate complexes with β-lactoglobulin
Creators: name: Shiri, Fereshteh
name: Shahraki, Somaye
name: Frozandeh-Moghadam, Hossein
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: The synthesis, characterization, antioxidant activity and β-LG interaction of two Zn(II) complexes formulated as [(N-N)Zn(µ-pr-dtc)Zn(N-N)](NO3)2] (where pr-dtc is propylenbisdithiocarbamate, N-N are 2,2′-bipyridine for complex a, and 1,10 phenanthroline for complex b) were reported. The in vitro antioxidant activity of the Zn complexes was evaluated against 1,1-diphenyl-2-picrylhydrazyl radicals (DPPH). Both complexes presented moderate antioxidant activity (IC50 = 231.0 ± 5.7 mg L−1 for complex a and 250.0 ± 6.1 mg L−1 for complex b). Fluorescence studies showed that the intrinsic fluorescence of β-LG was statically quenched by the prepared complexes mainly through Van der Waals interaction and hydrogen bond. The fluorescence results showed that the above complexes could bind with β-LG with a relatively strong affinity (complex a: Kb(27 °C) = 0.16 × 104 M−1, Kb(37 °C) = 0.06 × 104 M−1, complex b: Kb(27 °C) = 1.94 × 104 M−1, Kb(37 °C) = 0.11 × 104 M−1). The secondary structure of β-LG was changed in the presence of these Zn complexes and the decrease in α-helix (0.41% and 0.55% for complex a and complex b, respectively) and β-sheet (1.19% and 1.44% for complex a and complex b, respectively) contents confirmed the protein instability during the interaction. Molecular dynamics simulation was used during the preparation of the protein receptor before docking to find the best fit of the complexes to β-LG. Some details about molecular docking simulations describe Van der Waals interactions and hydrogen bonding, and this is in agreement with the thermodynamics data derived from fluorescence spectroscopy experiment. Communicated by Ramaswamy H. Sarma
Additional file 1 of Study of the inhibitory effects of chrysin and its nanoparticles on mitochondrial complex II subunit activities in normal mouse liver and human fibroblasts
Creators: name: Ragab, Eman M.
name: El Gamal, Doaa M.
name: Mohamed, Tarek M.
name: Khamis, Abeer A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Additional file 1: The ARRIVE Essential 10: Compliance Questionnaire.
Multispectroscopic analysis, atomic force microscopy, molecular docking and molecular dynamic simulation studies of the interaction between [SnMe2Cl2(Me2phen)] complex and ct-DNA in the presence of glucose
Creators: name: Shahabadi, Nahid
name: Mahdavi, Mohammad
name: Momeni, Badri Z.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: In this study, the spectroscopic methods (UV–vis, fluorimetric), Atomic force microscopy, and computational studies (molecular docking and molecular dynamic simulation) were used to investigate the interaction of [SnMe2Cl2(Me2phen)] complex with CT-DNA in the presence of glucose. The results showed the complex in the medium containing glucose has less effect on calf thymus DNA (ct-DNA) than the medium without glucose. Cytotoxicity of [SnMe2Cl2(Me2phen)] complex on MCF-7 cells was examined and showed Sn(IV) complex possesses potential cytotoxicity against this cell line. Molecular docking study showed that Sn(IV) complex interacts with DNA by groove binding mode. Radius of gyration (Rg) was smaller upon binding of the Sn(IV) complex suggesting a more compact structure of DNA in the presence of Sn(IV) complex. Communicated by Ramaswamy H. Sarma
Revisiting the Parallax of the Isolated Neutron Star RX J185635-3754 Using HST/ACS Imaging
Creators: name: Walter, F. M.
name: Eisenbeiss, T.
name: Lattimer, J. M.
name: Kim, B.
name: Hambaryan, V.
name: Neuhaeuser, R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We have redetermined the parallax and proper motion of the nearby isolated neutron star RX~J185635-3754. We used eight observations with the high resolution camera of the HST/ACS taken from 2002 through 2004. We performed the astrometric fitting using five independent methods, all of which yielded consistent results. The mean estimate of the distance is 123 (+11, -15) pc (1 sigma), in good agreement with our earlier published determination.
Computational analysis identifies druggable mutations in human rBAT mediated Cystinuria
Creators: name: Pandey, Bharati
name: Aarthy, Murali
name: Sharma, Mahima
name: Singh, Sanjeev Kumar
name: Kumar, Vinay
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Culex quinquefasciatus Cqm1 protein acts as the receptor for Lysinibacillus sphaericus mosquito-larvicidal binary (BinAB) toxin that is used worldwide for mosquito control. We found amino acid transporter protein, rBAT, as phylogenetically closest Cqm1 homolog in humans. The present study reveals large evolutionary distance between Cqm1 and rBAT, and rBAT ectodomain lacks the sequence motif which serves as binding-site for the BinAB toxin. Thus, BinAB toxin can be expected to remain safe for humans. rBAT (heavy subunit; SLC3A1) and catalytic b0,+AT (light subunit; SLC7A9), linked by single disulfide bond, mediate renal reabsorption of cystine and dibasic amino acids in Na+ independent manner. Mutations in rBAT cause type I Cystinuria disease which shows global prevalence, and rBAT can be thought as an important pharmacological target. However, 3D structures of rBAT and b0,+AT, the two components of b0,+ heteromeric amino acid transporter systems, are not available. We constructed a reliable homology model of rBAT using Cqm1 coordinates and that of transmembrane b0,+AT subunit using LAT1 coordinates. Mapping of pathogenic mutations onto rBAT ectodomain revealed their scattered distribution throughout the rBAT protein. Further, our computational simulations-based scoring of several known deleterious mutations of rBAT revealed that mutations those do not compromise the protein fold and stability, are localized on the same face of the molecule. These residues are expected to interact with the b0,+AT transporter. The present study thus identifies druggable sites on rBAT that could be targeted for the treatment of type I Cystinuria. Communicated by Ramaswamy H. Sarma
PEDAGOGICAL POSSIBILITIES OF THE DIAGNOSTIC THEORY OF SPEECH SKILLS OF STUDENTS WITHIN THE FRAMEWORK OF THE NATIONAL PROGRAM
Creators: name: Usmanova Diloromkhan Ziyodinovna Andijan State Pedagogical Institute, Department of pedagogy and psychology PhD. student Uzbekistan. Andijan.
Publisher: name: Zenodo
Year: 2025

description: the development of speech competence of students is one of the important tasks of the modern educational system. Improving the quality of education in Uzbekistan, developing oral and written speech of students, developing logical thinking is one of the priority areas of national educational programs. Therefore, this article analyzes the pedagogical possibilities of the theory of diagnosis of speech competence on the basis of the national program.

Keywords: speech competence, diagnostics, oral and written speech, unified national assessment standard, modern education
A critical analysis of the role of law and feminist legal approaches in women’s life advancement : a case study of the one million signatures campaign
Creators: name: Olyaei, Shiva
Publisher: name: University of British Columbia
Year: 2018

description: Iranian women carry the legacy of five generations of women’s activism over the last 150 years. Through a feminist legal lens, this dissertation surveys this rich history, especially the One Million Signatures Campaign (OMSC). The dissertation raises two major questions. (1) Whether there has been too much emphasis on law and legal reform as means to achieve gender justice in Iranian feminist movements at the expense of other approaches. (2) Whether using certain aspects of liberal and radical feminism as methodologies turned the OMSC into the reflecting surface of the western feminist centre, thus failing to contextualize their work within their sociopolitical and cultural region. This dissertation sheds light on the theoretical and methodological possibilities of drawing more on postmodernist and Third world feminist approaches. Through historical, textual and discourse analysis, this dissertation explores legal centralist liberal feminism and radical feminism as influential western tropes in contemporary Iranian feminism. Deconstructive postmodern and TW feminism, which tackle universalist and orientalist tendencies in feminist scholarship, are suggested as pertinent approaches for Iranian feminism. Honouring the legacy of and historicizing five generations of Iranian women’s activism, this dissertation complicates earlier categorizations by highlighting class, ideology and religion. OMSC is critically analysed, including its emergence and demise, its strategic legal demands suggesting a paradigm shift from traditional readings of Shari’a law to secular CEDAW norms, and its discursive engagement with western feminism. By referring to data on the status of Iranian women, this research shows that formal legal indicators fail to capture Iranian feminist praxis in the so-called ‘repressed post-revolutionary era’. It is argued that law cannot be portrayed as the sole factor responsible for stagnation or advancement in women’s lives, as it glosses over how women defy, negotiate, and even bypass discriminatory laws and ideologies. Moreover, it is crucial that future Iranian feminist activism shift its theoretical groundings from hegemonic western feminist legal theory to postmodern and TW feminism. The latter approaches not only de-center law wherever possible, but discursively engage with it. They also challenge totalizing feminist knowledge that homogenizes and universalizes feminist struggles under western feminist standards.