cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Poking holes and cutting corners to achieve Clifford gates with the surface code
Creators: name: Brown, Benjamin J.
name: Laubscher, Katharina
name: Kesselring, Markus S.
name: Wootton, James R.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The surface code is currently the leading proposal to achieve fault-tolerant quantum computation. Among its strengths are the plethora of known ways in which fault-tolerant Clifford operations can be performed, namely, by deforming the topology of the surface, by the fusion and splitting of codes and even by braiding engineered Majorana modes using twist defects. Here we present a unified framework to describe these methods, which can be used to better compare different schemes, and to facilitate the design of hybrid schemes. Our unification includes the identification of twist defects with the corners of the planar code. This identification enables us to perform single-qubit Clifford gates by exchanging the corners of the planar code via code deformation. We analyse ways in which different schemes can be combined, and propose a new logical encoding. We also show how all of the Clifford gates can be implemented with the planar code without loss of distance using code deformations, thus offering an attractive alternative to ancilla-mediated schemes to complete the Clifford group with lattice surgery.
description: 18 pages, 15 figures, comments welcome; v2 - improvements and clarifications given in the manuscript. No significant changes in the main conclusions; v3 - same as v2 with corrected fig. 2 and ; v4 - minor changes following peer review. One new figure; v5 - version to be published, final author copy, minor typos and mistakes corrected
Meaning of the field dependence of the renormalization scale in Higgs inflation
Creators: name: Hamada, Yuta
name: Kawai, Hikaru
name: Nakanishi, Yukari
name: Oda, Kin-ya
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider the prescription dependence of the Higgs effective potential under the presence of general nonminimal couplings. We evaluate the fermion loop correction to the effective action in a simplified Higgs-Yukawa model whose path integral measure takes simple form either in the Jordan or Einstein frame. The resultant effective action becomes identical in both cases when we properly take into account the quartically divergent term coming from the change of measure. Working in the counterterm formalism, we clarify that the difference between the prescriptions I and II comes from the counter term to cancel the logarithmic divergence. This difference can be absorbed into the choice of tree-level potential from the infinitely many possibilities, including all the higher-dimensional terms. We also present another mechanism to obtain a flat potential by freezing the running of the effective quartic coupling for large field values, using the nonminimal coupling in the gauge kinetic function.
description: 19 pages; version to appear in Phys. Rev. D; title changed according to editor's request; paragraphs added in the end of Secs. 3.3 and 4; minor modifications
Dieter Seitz: "Per Order de Mufti läuft nichts". Zur sozialen Steuerung betrieblicher Gestaltungsprozesse, Berlin: edition sigma, 1993, ISBN 3-89404-364-4, 284 S., DM 32,80
Creators: name: Peter, Gerd
Publisher: name: Westdeutscher Verlag
Year: 1994
Subjects: subject: 300
subject: 650

description: Arbeit
Challenges, rewards, and psychological distress among conservationists: Key findings and ideas for employers
Creators: name: Pienkowski, Thomas
name: Keane, Aidan
name: Castelló y Tickell, Sofia
name: de Lange, Emiel
name: Hazenbosch, Mirjam
name: Khanyari, Munib
name: Arlidge, William N.S.
name: Baranyi, Gergő
name: Brittain, Stephanie
name: Kapoor, Vena
name: Mohan, Vik
name: Papworth, Sarah
name: Ravi, Roshni
name: Smit, Izak
name: Milner-Gulland, E.J.
Publisher: name: figshare
Year: 2022
Subjects: subject: 50202 Conservation and Biodiversity
subject: FOS: Biological sciences

description: This document summarises key findings of the project and shares ideas for practical steps that employers might find useful for supporting the mental health and wellbeing of staff. The document also contains links to external resources that might be useful.
Destabilization of Aβ fibrils by omega-3 polyunsaturated fatty acids: a molecular dynamics study
Creators: name: Gupta, Shivani
name: Dasmahapatra, Ashok Kumar
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology

description: The senile plaques of neurotoxic aggregates of Aβ protein, deposited extraneuronally, mark the pathological hallmark of Alzheimer’s disease (AD). The natural compounds such as omega-3 (ω-3) polyunsaturated fatty acids (PUFAs), which can access blood–brain barrier, are believed to be potential disruptors of preformed Aβ fibrils to cure AD with unknown mechanism. Herein, we present the destabilization potential of three ω-3 PUFAs, viz. Eicosapentaenoic acid (EPA), Docosahexaenoic acid (HXA), and α-linolenic acid (LNL) by molecular dynamics simulation. After an initial testing of 300 ns, EPA and HXA have been considered further for extended production run time, 500 ns. The increased value of root mean square deviation (RMSD), radius of gyration, and solvent-accessible surface area (SASA), the reduced number of H-bonds and β-sheet content, and disruption of salt bridges and hydrophobic contacts establish the binding of these ligands to Aβ fibril leading to destabilization. The polar head was found to interact with positively charged lysine (K28) residue in the fibril. However, the hydrophobicity of the long aliphatic tail competes with the intrinsic hydrophobic interactions of Aβ fibril. This amphiphilic nature of EPA and HXA led to the breaking of inherent hydrophobic contacts and formation of new bonds between the tail of PUFA and hydrophobic residues of Aβ fibril, leading to the destabilization of fibril. The Molecular Mechanics Poisson–Boltzmann Surface Area (MM-PBSA) results explain the binding of EPA and HXA to Aβ fibril by interacting with different residues. The destabilization potential of EPA and HXA establishes them as promising drug leads to cure AD, and encourages prospecting of other fatty acids for therapeutic intervention in AD. Communicated by Ramaswamy H. Sarma
A performance comparison of continuous and discontinuous Galerkin methods with fast multigrid solvers
Creators: name: Kronbichler, Martin
name: Wall, Wolfgang A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: G.1.8

description: This study presents a fair performance comparison of the continuous finite element method, the symmetric interior penalty discontinuous Galerkin method, and the hybridized discontinuous Galerkin method. Modern implementations of high-order methods with state-of-the-art multigrid solvers for the Poisson equation are considered, including fast matrix-free implementations with sum factorization on quadrilateral and hexahedral elements. For the hybridized discontinuous Galerkin method, a multigrid approach that combines a grid transfer from the trace space to the space of linear finite elements with algebraic multigrid on further levels is developed. Despite similar solver complexity of the matrix-based HDG solver and matrix-free geometric multigrid schemes with continuous and discontinuous Galerkin finite elements, the latter offer up to order of magnitude faster time to solution, even after including the superconvergence effects. This difference is because of vastly better performance of matrix-free operator evaluation as compared to sparse matrix-vector products. A roofline performance model confirms the advantage of the matrix-free implementation.
Bodily responsiveness and corporeal ethics in lyengar yoga, Foucault, Irigaray, Levinas and Derrida
Creators: name: Dean., Liz
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Intrinsic Electrical Transport and Performance Projections of Synthetic Monolayer MoS2 Devices
Creators: name: Smithe, Kirby K. H.
name: English, Chris D.
name: Suryavanshi, Saurabh V.
name: Pop, Eric
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate monolayer MoS2 grown by chemical vapor deposition (CVD) with transport properties comparable to those of the best exfoliated devices over a wide range of carrier densities (up to ~10^13 1/cm^2) and temperatures (80-500 K). Transfer length measurements reveal monolayer mobility of ~20 cm2/V/s on SiO2 substrates at 300 K and practical carrier densities (>2x10^12 1/cm^2). We also demonstrate the highest current density reported to date (~270 uA/um or 44 MA/cm^2) at 300 K for an 80 nm device from CVD-grown monolayer MoS2. Using simulations, we discuss what improvements of monolayer MoS2 are still required to meet technology roadmap requirements for low power (LP) and high performance (HP) applications. Such results are an important step towards large-area electronics based on monolayer semiconductors.
description: to be published in 2D Materials
On entanglement entropy in non-Abelian lattice gauge theory and 3D quantum gravity
Creators: name: Delcamp, Clement
name: Dittrich, Bianca
name: Riello, Aldo
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Entanglement entropy is a valuable tool for characterizing the correlation structure of quantum field theories. When applied to gauge theories, subtleties arise which prevent the factorization of the Hilbert space underlying the notion of entanglement entropy. Borrowing techniques from extended topological field theories, we introduce a new definition of entanglement entropy for both Abelian and non-Abelian gauge theories. Being based on the notion of excitations, it provides a completely relational way of defining regions. Therefore, it naturally applies to background independent theories, e.g. gravity, by circumventing the difficulty of specifying the position of the entangling surface. We relate our construction to earlier proposals and argue that it brings these closer to each other. In particular, it yields the non-Abelian analogue of the "magnetic centre choice", as obtained through an extended-Hilbert-space method, but applied to the recently introduced fusion basis for 3D lattice gauge theories. We point out that the different definitions of entanglement theory can be related to a choice of (squeezed) vacuum state.
description: 25 pages + Appendices
Hen lysozyme fibrillogenesis, molten globule intermediate and effect of copper salts
Creators: name: Cerón, Ricardo
name: Peimbert, Mariana
name: Rojo-Domínguez, Arturo
name: Nájera, Hugo
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Inorganic Chemistry

description: The amyloid fibres have been related to many diseases. The molten globule intermediate has been proposed to form part of the folding pathway of many proteins. In the present study, we investigated the mechanism of amyloid-fibres formation of hen egg-white lysozyme (HEWL) incubated in a potassium phosphate buffer, pH 11.8, 100 mM, at 37 °C for 30 h, and evaluated the influence of Cu(II) present in two salts (CuSO4 and CuCl2) during fibrillogenesis. Co-incubation and post-incubation of lysozyme with copper salts reduced the fluorescence signal of thioflavin T with an increment in the intrinsic fluorescence of the protein. The ANS fluorescence test showed that incubation of HEWL for 6 h generated a molten globule intermediate state that formed amyloid fibres when incubation was carried out for a 30-h timespan. Dynamic light scattering showed a heterogeneous population of states in samples incubated in the absence or the presence of salts during the fibrillation process. The existence of a reducing potential was verified during the formation of HEWL amyloid fibres with the bathocuproine disulphonate test. Transmission electron microscopy confirmed the presence and absence of fibres in solutions incubated with and without Cu(II). This work demonstrated that lysozyme formed amyloid fibres at 37 °C and copper inhibited its formation. Communicated by Ramaswamy H. Sarma
(202093) Rosina Agneta Forte
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Consistency of the Planck CMB data and $Λ$CDM cosmology
Creators: name: Shafieloo, Arman
name: Hazra, Dhiraj Kumar
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We test the consistency between Planck temperature and polarization power spectra and the concordance model of $Λ$ Cold Dark Matter cosmology ($Λ$CDM) within the framework of Crossing statistics. We find that Planck TT best fit $Λ$CDM power spectrum is completely consistent with EE power spectrum data while EE best fit $Λ$CDM power spectrum is not consistent with TT data. However, this does not point to any systematic or model-data discrepancy since in the Planck EE data, uncertainties are much larger compared to the TT data. We also investigate the possibility of any deviation from $Λ$CDM model analyzing the Planck 2015 data. Results from TT, TE and EE data analysis indicate that no deviation is required beyond the flexibility of the concordance $Λ$CDM model. Our analysis thus rules out any strong evidence for beyond the concordance model in the Planck spectra data. We also report a mild amplitude difference comparing temperature and polarization data, where temperature data seems to have slightly lower amplitude than expected (consistently at all multiples), as we assume both temperature and polarization data are realizations of the same underlying cosmology.
description: 19 pages, 11 figures, analysis and discussions extended including TE data, main results unchanged, matches the final version published in JCAP
The reconstruction of Quaternary vegetation and climate on King Island, Bass Strait, Australia
Creators: name: D'Costa., Donna Marie
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Improvements and Testing Practical Expressions for Photon Strength Functions of E1 Gamma-Transitions
Creators: name: Plujko, Vladimir
name: Gorbachenko, Oleksandr
name: Kadenko, Igor
name: Solodovnyk, Kateryna
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Analytical expression for the E1 photon strength functions (PSF) is modified to account for the low-energy enhancement due to nuclear structure effects (presence of low-energy state (LES)). A closed-form expression of the E1 PSF function includes response of two nuclear states: LES and giant diplole resonance (GDR). Expression for the nuclear response function on electromagnetic field is based on a model of excitation of two coupled damped states. These approach is tested for different data sets for spherical nuclei. Impact on PSF shape of coupling between LES and GDR excitations is considered.
description: 4 pages, 3 figures; 1st part of the report on International Conference on Nuclear Data for Science and Technology (ND2016), (changes in table 3)
In silico screening and covalent binding of phytochemicals of Ocimum sanctum against SARS-CoV-2 (COVID 19) main protease
Creators: name: Mohapatra, Pranab Kishor
name: Chopdar, Kumar Sambhav
name: Dash, Ganesh Chandra
name: Mohanty, Abhay Kumar
name: Raval, Mukesh Kumar
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Computational Biology

description: Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has compelled the scientific community to search for an effective drug that can cure or a vaccine that can prevent the disease. Alternatively, symptomatic treatment and traditional immunity boosters are prescribed. Holy Tulsi (Ocimum sanctum) has been known as an ancient remedy for cure of common cold and respiratory ailment. Several reports have come on virtual screening of phytochemicals including those of Tulsi against various enzymes of the virus. We undertook in silico analysis of the ethanol extracted phytochemicals of Tulsi as inhibitors of SARS-CoV-2 (2019-nCoV) main protease with an approach to look into the possibility of covalent ligand binding with the catalytic residue Cys145, which makes the report unique. The results suggest that the flavonoids and polyphenolic compounds of Tulsi, have potential to covalently bind to the catalytic residue Cys145 of main protease and irreversibly inhibit the viral enzyme. Luteolin-7-O-glucuronide is specially considered for its optimum properties, namely, low toxicity (LD50 5000 mg/kg body weight), high drug-likeness score (0.71), the active site binding free energy (ΔGbind) −19.19 kcal/mol by GBSA method and covalent binding energy −24.23 kcal/mol. Further experimental validations are required to establish the theoretical findings. Communicated by Ramaswamy H. Sarma
Hierarchy of orientational phases and axial anisotropies in the gauge theoretical description of generalized nematics
Creators: name: Liu, Ke
name: Nissinen, Jaakko
name: de Boer, Josko
name: Slager, Robert-Jan
name: Zaanen, Jan
Publisher: name: arXiv
Year: 2016
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The paradigm of spontaneous symmetry breaking encompasses the breaking of the rotational symmetries $O(3)$ of isotropic space to a discrete subgroup, i.e. a three-dimensional point group. The subgroups form a rich hierarchy and allow for many different phases of matter with orientational order. Such spontaneous symmetry breaking occurs in nematic liquid crystals and a highlight of such anisotropic liquids are the uniaxial and biaxial nematics. Generalizing the familiar uniaxial and biaxial nematics to phases characterized by an arbitrary point group symmetry, referred to as \emph{generalized nematics}, leads to a large hierarchy of phases and possible orientational phase transitions. We discuss how a particular class of nematic phase transitions related to axial point groups can be efficiently captured within a recently proposed gauge theoretical formulation of generalized nematics [K. Liu, J. Nissinen, R.-J. Slager, K. Wu, J. Zaanen, Phys. Rev. X {\bf 6}, 041025 (2016)]. These transitions can be introduced in the model by considering anisotropic couplings that do not break any additional symmetries. By and large this generalizes the well-known uniaxial-biaxial nematic phase transition to any arbitrary axial point group in three dimensions. We find in particular that the generalized axial transitions are distinguished by two types of phase diagrams with intermediate vestigial orientational phases and that the window of the vestigial phase is intimately related to the amount of symmetry of the defining point group due to inherently growing fluctuations of the order parameter. This might explain the stability of the observed uniaxial-biaxial phases as compared to the yet to be observed other possible forms of generalized nematic order with higher point group symmetries.
description: 14 pages, 6 figures; published version
Discourse functions of demonstratives and place adverbs with exophoric reference in Logea, an Oceanic language of Papua New Guinea
Creators: name: Dawuda., Carmen
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
(202094) Esmee Daisy Forbes
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
An electrically driven spin qubit based on valley mixing
Creators: name: Huang, Wister
name: Veldhorst, Menno
name: Zimmerman, Neil M.
name: Dzurak, Andrew S.
name: Culcer, Dimitrie
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The electrical control of single spin qubits based on semiconductor quantum dots is of great interest for scalable quantum computing since electric fields provide an alternative mechanism for qubit control compared with magnetic fields and can also be easier to produce. Here we outline the mechanism for a drastic enhancement in the electrically-driven spin rotation frequency for silicon quantum dot qubits in the presence of a step at a hetero-interface. The enhancement is due to the strong coupling between the ground and excited states which occurs when the electron wave-function overcomes the potential barrier induced by the interface step. We theoretically calculate single qubit gate times of 170ns for a quantum dot confined at a silicon/silicon-dioxide interface. The engineering of such steps could be used to achieve fast electrical rotation and entanglement of spin qubits despite the weak spin-orbit coupling in silicon.
A Pilot-Study on Vibration Therapy Pad: its Mode of Vibration and Effectiveness
Creators: name: Yar, Usama Bin
Publisher: name: Zenodo
Year: 2022
Subjects: Pilot study, Vibration therapy, Physiotherapy, Rehabilitation, Sports Medicine.

description: Background: Vibration therapy is a type of treatment that improves physical health and is effective in assisting patients in their recovery. Following that, the vibration therapy pad (VTP) is designed to contribute to the health sector but with a different approach. Usually, the vibration therapy devices stimulate the muscles through longitudinal waves, but the vibration-therapy pad stimulates the muscles through transverse waves with the localized vibrational method. As this device “Vibration Therapy Pad”, is going through a pilot study and the core aim is to evaluate its effectiveness. Methodology: CONSORT 2010 checklist was used to report the study. Moreover, a total of 30 participants were recruited and recorded data included a continuous series of physical activities. To check the vibration therapy pad's effectivity, the data was divided according to intensity of pain after a set of activities (mild, moderate and no pain) and felt after using the device (VTP) while this was evaluated using physical examination and Visual Analysis Scale. Results: The hypothesis of the Yarz principle is valid and the mode of vibration of the device can be practised. Whilst analyzing its effectiveness, the results were satisfactory. As 76.66% felt that the pain was transferred from severe to moderate and 23.30% of participants noticed a shift from moderate to no pain. And probability p<0.05 shows results were significant when analyzing VAS. Conclusions: It is concluded that, after going through the pilot study, VTP was found to be an effective device for vibration therapy, which can aid in enhancing muscular functioning and physical capability. It was also discovered that Yarz-principle, i.e. its mode of vibration, is an applicable technique to be practised.
Towards a radical empiricism : dynamic ontology in the thought of Gilles Deleuze and Luce Irigaray
Creators: name: Davies., Jeff MacRae
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
A systematic drug repurposing approach to identify promising inhibitors from FDA-approved drugs against Nsp4 protein of SARS-CoV-2
Creators: name: Chakraborty, Joydeep
name: Maity, Atanu
name: Sarkar, Hironmoy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: COVID-19 is caused by SARS-CoV-2 and responsible for the ongoing global pandemic in the world. After more than a year, we are still in lurch to combat and control the situation. Therefore, new therapeutic options to control the ongoing COVID-19 are urgently in need. In our study, we found that nonstructural protein 4 (Nsp4) of SARS-CoV-2 could be a potential target for drug repurposing. Due to availability of only the crystal structure of C-terminal domain of Nsp4 (Ct-Nsp4) and its crucial participation in viral RNA synthesis, we have chosen Ct-Nsp4 as a target for screening the 1600 FDA-approved drugs using molecular docking. Top 102 drugs were found to have the binding energy equal or less than –7.0 kcal/mol. Eribulin and Suvorexant were identified as the two most promising drug molecules based on the docking score. The dynamics of Ct-Nsp4-drug binding was monitored using 100 ns molecular dynamics simulations. From binding free energy calculation over the simulation, both the drugs were found to have considerable binding energy. The present study has identified Eribulin and Suvorexant as promising drug candidates. This finding will be helpful to accelerate the drug discovery process against COVID-19 disease. Communicated by Ramaswamy H. Sarma
The use of Coleus amboinicus lour as a lactagogue among lactating women in Simalungun district, north Sumatra province
Creators: name: Damanik., Muhammad Rizal Martua
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
(202096) Adelaide Elizabeth Orde
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Amtliche Mitteilungen der Technischen Universität Dortmund Nr. 9/2013
Creators: name: (:Unkn) Unknown
Publisher: name: Technische Universität Dortmund
Year: 2013
Subjects: subject: 080

description: Gleichstellungskonzept der Fakultät für Informatik (2011 bis 2013)
description: Zweite Ordnung zur Änderung der Verwaltungs- und Benutzungsordnung für die Sozialforschungsstelle der Technischen Universität Dortmund vom 25.06.2007 (AM 10/2007), zuletzt geändert durch Änderungsordnung vom 14.12.2007 (AM 21/2007)
description: Amtliche Mitteilungen der Technischen Universität Dortmund ; 9, 2013
Tracing Primordial Black Holes in Nonsingular Bouncing Cosmology
Creators: name: Chen, Jie-Wen
name: Liu, Junyu
name: Xu, Hao-Lan
name: Cai, Yi-Fu
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We in this paper investigate the formation and evolution of primordial black holes (PBHs) in nonsingular bouncing cosmologies. We discuss the formation of PBH in the contracting phase and calculate the PBH abundance as a function of the sound speed and Hubble parameter. Afterwards, by taking into account the subsequent PBH evolution during the bouncing phase, we derive the density of PBHs and their Hawking radiation. Our analysis shows that nonsingular bounce models can be constrained from the backreaction of PBHs.
description: 19 pages, 4 figures, comments are welcome
Out of the shadow : reconstructing Frieda Strehlow as missionary wife in Central Australia, 1895-1922
Creators: name: Curtis-Wendlandt., Lisa
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Exploring potential of Plasmodium RUVBL proteins as anti-malarial drug target
Creators: name: Khurana, Juhi
name: Shrivastava, Ashish
name: Singh, Ashutosh
name: Gupta, Ashish
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Although malaria related cases and deaths have consistently declined over time, growing resistance to existing anti-malarial drugs in Plasmodium remains a matter of extreme concern. Since we rely so heavily on use of chemotherapy for malaria treatment and knowing that all the available anti-malarial drug will become virtually useless in the near future, we have to increase our understanding of basic biology of the parasite as well as characterize new molecular targets that can be exploited for anti-malarial therapy. In the present study, PfRUVBLs (AAA family member proteins) were evaluated for their potential as novel anti-malarial drug target candidates, using computational approaches. Virtual High-throughput screening of various pharmacophore libraries obtained from three different databases (which included, Asinex, ZINC15 & PubChem) followed by extra precision docking, resulted in identification of relevant hit compounds that showed binding affinity with the active region of PfRUVBL1 protein. Based on molecular docking data, MD simulations, and protein-ligand interaction studies, combined with toxicity assessment & ADME profiling data, at least three best hits were eventually identified that could be novel potent inhibitors of PfRUVBL1 protein and can be further tested for anti-malarial activity using in vitro protocols. Communicated by Ramaswamy H. Sarma
From degree-correlated to payoff-correlated activity for an optimal resolution of social dilemmas
Creators: name: Aleta, Alberto
name: Meloni, Sandro
name: Perc, Matjaz
name: Moreno, Yamir
Publisher: name: arXiv
Year: 2016
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: An active participation of players in evolutionary games depends on several factors, ranging from personal stakes to the properties of the interaction network. Diverse activity patterns thus have to be taken into account when studying the evolution of cooperation in social dilemmas. Here we study the weak prisoner's dilemma game, where the activity of each player is determined in a probabilistic manner either by its degree or by its payoff. While degree-correlated activity introduces cascading failures of cooperation that are particularly severe on scale-free networks with frequently inactive hubs, payoff-correlated activity provides a more nuanced activity profile, which ultimately hinders systemic breakdowns of cooperation. To determine optimal conditions for the evolution of cooperation, we introduce an exponential decay to payoff-correlated activity that determines how fast the activity of a player returns to its default state. We show that there exists an intermediate decay rate, at which the resolution of the social dilemma is optimal. This can be explained by the emerging activity patterns of players, where the inactivity of hubs is compensated effectively by the increased activity of average-degree players, who through their collective influence in the network sustain a higher level of cooperation. The sudden drops in the fraction of cooperators observed with degree-correlated activity therefore vanish, and so does the need for the lengthy spatiotemporal reorganization of compact cooperative clusters. The absence of such asymmetric dynamic instabilities thus leads to an optimal resolution of social dilemmas, especially when the conditions for the evolution of cooperation are strongly adverse.
description: 8 two-column pages, 6 figures; accepted for publication in Physical Review E
(202097) Oswald Vernon Forbes
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Interactions of chlorophyll-derived photosensitizers with human serum albumin are determined by the central metal ion
Creators: name: Szafraniec, Milena J.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Two structurally similar derivatives of chlorophyll a, chlorophyllide a (Chlide) and zinc-pheophorbide a (Zn-Pheide), differing only in central metal ion (Mg2+ or Zn2+, respectively) substituting the tetrapyrrole ring, were investigated with regard to their binding to human serum albumin (HSA). Chlide and Zn-Pheide are very promising photosensitizers with potential application in photodynamic therapy, therefore it is desirable to investigate their interactions with serum proteins. The studies included absorption and steady-state fluorescence spectroscopy, as well as molecular docking. It was found that both investigated compounds form complexes with HSA. Experimental data revealed two classes of binding sites for each compound. The affinities (Ka) for the first class were in the range of 105 and 106 M−1 for Chlide and Zn-Pheide, respectively, while the second class was characterized by the affinities of the order of 104 M−1 for both derivatives. Molecular docking simulations together with displacement studies revealed that the primary binding site of the studied compounds is the heme site, localized in the subdomain IB, however the best characterized binding sites of HSA, namely the Sudlow’s sites I and II are also involved. The interactions between the derivatives of chlorophyll and HSA were found to be predominantly hydrophobic and to a lesser extent hydrogen bonding. Our results demonstrate that the centrally bound metal ion determines both the affinity and mode of binding to HSA, which may be a feature differentiating these compounds in terms of their pharmacokinetics. Communicated by Ramaswamy H. Sarma
A Haar Wavelet-Based Perceptual Similarity Index for Image Quality Assessment
Creators: name: Reisenhofer, Rafael
name: Bosse, Sebastian
name: Kutyniok, Gitta
name: Wiegand, Thomas
Publisher: name: arXiv
Year: 2016
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In most practical situations, the compression or transmission of images and videos creates distortions that will eventually be perceived by a human observer. Vice versa, image and video restoration techniques, such as inpainting or denoising, aim to enhance the quality of experience of human viewers. Correctly assessing the similarity between an image and an undistorted reference image as subjectively experienced by a human viewer can thus lead to significant improvements in any transmission, compression, or restoration system. This paper introduces the Haar wavelet-based perceptual similarity index (HaarPSI), a novel and computationally inexpensive similarity measure for full reference image quality assessment. The HaarPSI utilizes the coefficients obtained from a Haar wavelet decomposition to assess local similarities between two images, as well as the relative importance of image areas. The consistency of the HaarPSI with the human quality of experience was validated on four large benchmark databases containing thousands of differently distorted images. On these databases, the HaarPSI achieves higher correlations with human opinion scores than state-of-the-art full reference similarity measures like the structural similarity index (SSIM), the feature similarity index (FSIM), and the visual saliency-based index (VSI). Along with the simple computational structure and the short execution time, these experimental results suggest a high applicability of the HaarPSI in real world tasks.
Amtliche Mitteilungen der Universität Dortmund Nr. 07/98
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Dortmund
Year: 1998
Subjects: subject: 080

description: 8. Satzung zur Änderung der Satzung der Studentenschaft der Universität Dortmund vom 4. September 1984 (AM 10/84), zuletzt geändert am 23. 1. 96 (AM 2/97)
description: Verwaltungs- und Benutzungsordnung des Instituts für Bauforschung der Fakultät Bauwesen der Universität Dortmund vom 6. November 1996
description: Amtliche Mitteilungen der Universität Dortmund ; 7, 1998
Generic uniqueness of the bias vector of finite stochastic games with perfect information
Creators: name: Akian, Marianne
name: Gaubert, Stéphane
name: Hochart, Antoine
Publisher: name: arXiv
Year: 2016
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 47J10, 91A20, 93E20

description: Mean-payoff zero-sum stochastic games can be studied by means of a nonlinear spectral problem. When the state space is finite, the latter consists in finding an eigenpair $(u,λ)$ solution of $T(u)=λe + u$, where $T:\mathbb{R}^n \to \mathbb{R}^n$ is the Shapley (or dynamic programming) operator, $λ$ is a scalar, $e$ is the unit vector, and $u \in \mathbb{R}^n$. The scalar $λ$ yields the mean payoff per time unit, and the vector $u$, called the bias, allows one to determine optimal stationary strategies. The existence of the eigenpair $(u,λ)$ is generally related to ergodicity conditions. A basic issue is to understand for which classes of games the bias vector is unique (up to an additive constant). In this paper, we consider perfect-information zero-sum stochastic games with finite state and action spaces, thinking of the transition payments as variable parameters, transition probabilities being fixed. We show that the bias vector, thought of as a function of the transition payments, is generically unique (up to an additive constant). The proof uses techniques of max-plus (or tropical) algebra and nonlinear Perron-Frobenius theory. As an application of our results, we obtain a perturbation scheme allowing one to solve degenerate instances of stochastic games by policy iteration.
Euaesthetus brachypterus Puthz 2014, nov.sp.
Creators: name: Puthz, V.
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Euaesthetus
Euaesthetus brachypterus

description: Euaesthetus brachypterus nov.sp. (Abb. 85, 88)
T y p u s m a t e r i a l: Holotypus (): U.S.A.: North Carolina, Haywood/ Jackson Co. Line, Waterrock Knob, Off Blue Ridge Parkway & Mile Post 450 5819-6200‘, 35 o 27.36’N, 83 o 8.26’W, under moss mats & berlese samples of moss covering large boulders and outcrops along trail, 29.X. 20067, K. D. Karns: im AMNH.
B e s c h r e i b u n g: Brachypter, dunkelbraun, Vorderkörper mässig glänzend, Abdomen schimmernd, Vorderkörper mässig grob, dicht punktiert, Abdomen sehr fein,äusserst dicht skulptiert; Beborstung dicht, anliegend. Kiefertaster und Fühler bräunlichgelb, Beine rötlichbraun.
L ä n g e: 1,5mm (Vorderkörperlänge: 0,8mm).
PM des HT: HW: 43; DE: 34; LE: 10; LT: 4; PW: 43; PL: 40; EW: 52; EL: 5; SL: 23.
M ä n n c h e n: Vordersternite einfach. 8. Sternit (Abb. 85). 9. Sternit apikomedian spitz. Aedoeagus (Abb. 88), Parameren apikal zweispitzig, mit 2 apikalen, 1 subapikalen starken Borste sowie mit je zwei feinen seitlichen Borsten.
W e i b c h e n: Unbekannt.
Kopf so breit wie das Pronotum, Augen vergleichsweise klein, Schläfen gut ein Drittel so lang wie die Augen, Punktierung mässig grob, dicht, Punkte etwa so gross wie der basale Querschnitt des 4. Fühlergliedes, Punktabstände, auch in der Mitte, kleiner als die Punkte. Fühler wie bei den Verwandten. Pronotum breiter als lang, vorn seitlich langkonvex, hinten, kaum konkav, eingezogen; in der Hinterhälfte jederseits der Mitte wird je ein schwacher Eindruck erkennbar; Punktierung wenig gröber als auf der Stirn, etwa ebenso dicht. Elytren trapezoid, viel breiter als lang, Schultern gänzlich abgeschrägt, mit einem winzigen Zähnchen, Seiten kräftig anch hinten erweiztert; Punktierung etwas feiner als am Pronotum und auch etwas weniger dicht, Punktabstände aber überwiegend kleiner als die Punkte.
D i f f e r e n z i a l d i a g n o s e: Diese neue Art lässt sich anhand ihren trapezoiden, kurzen Elytren nur mit Eu. scabripennis nov.sp. verwechseln. Von ihm unterscheidet sie sich sofort durch ihre dunkle Färbung, die fehlenden scharfen Längseindrücke des Pronotums und ihre Elytrenskulptur; vgl. auch die Bestimmungstabelle.
E t y m o l o g i e: Wegen ihrer kurzen Elytren nenne ich diese neue Art " brachypterus " (Griech.-Lat. = kurzflüglig).
description: Published as part of Puthz, V., 2014, Nordamerikanische Arten der Gattung Euaesthetus GRAVENHORST (Coleoptera, Staphylinidae) 115. Beitrag zur Kenntnis der Euaesthetinen, pp. 845-876 in Linzer biologische Beiträge 46 (1) on pages 866-867, DOI: 10.5281/zenodo.5306859
Fundamental limitation on quantum broadcast networks
Creators: name: Bäuml, Stefan
name: Azuma, Koji
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The ability to distribute entanglement over complex quantum networks is an important step towards a quantum internet. Recently, there has been significant theoretical effort, mainly focusing on the distribution of bipartite entanglement via a simple quantum network composed only of bipartite quantum channels. There are, however, a number of quantum information processing protocols based on multipartite rather than bipartite entanglement. Whereas multipartite entanglement can be distributed by means of a network of bipartite channels, a more natural way is to use a more general network, that is, a quantum broadcast network including quantum broadcast channels. In this work, we present a general frame- work for deriving upper bounds on the rates at which GHZ states or multipartite private states can be distributed among a number of different parties over an arbitrary quantum broadcast network. Our upper bounds are written in terms of the multipartite squashed entanglement, corresponding to a generalisation of recently derived bounds [K. Azuma et al., Nat. Commun. 7, 13523 (2016)]. We also discuss how lower bounds can be obtained by combining a generalisation of an aggregated quantum repeater protocol with graph theoretic concepts.
description: 16 pages, 2 figures, published version