cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
(2019) Elizabeth Humble
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Identification of a Novel RalGDS-related Protein as a Candidate Effector for Ras and Rap1
Creators: name: Lapetina, Eduarde G.
name: Brtva, Teresa R.
name: Fischer, Thomas
name: Altschuler, Daniel L.
name: Martelli, Paola
name: Der, Channing J.
name: White II, Gilbert C.
name: Peterson, Scott N.
name: Trabalzini, Lorenza
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Although Ras and Rap1 share interaction with common candidate effector proteins, Rap1 lacks the transforming activity exhibited by Ras proteins. It has been speculated that Rap antagonizes Ras transformation through the formation of nonproductive complexes with critical Ras effector targets. To understand further the distinct biological functions of these two closely related proteins, we searched for Rap1b-binding proteins by yeast two-hybrid screening. We identified multiple clones that encode the COOH-terminal sequences of a protein that shares sequence identity with RalGDS and RGL, which we have designated RGL2. A 158-amino acid COOH-terminal fragment of RGL2 (RGL2 C-158) bound to Ras superfamily proteins which shared identical effector domain sequences with Rap1 (Ha-Ras, R-Ras, and TC21). RGL2 C-158 binding was impaired by effector domain mutations in Rap1b and Ha-Ras. Furthermore, RGL2 C-158 bound exclusively to the GTP-, but not the GDP-bound form of Ha-Ras. Finally, coexpression of RGL2 C-158 impaired oncogenic Ras activation of transcription from a Ras-responsive promoter element and focus-forming activity in NIH 3T3 cells. We conclude that RGL2 may be an effector for Ras and/or Rap proteins.
Computational homogenization of higher-order continua
Creators: name: Schmidt, Felix
name: Krüger, Melanie
name: Keip, Marc-Andre
name: Hesch, Christian
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: We introduce a novel computational framework for the multiscale simulation of higher-order continua that allows for the consideration of first-, second- and third- order effects at both micro- and macro-level. In line with classical two-scale approaches, we describe the microstructure via representative volume elements (RVE) that are attached at each integration point of the macroscopic problem. To take account of the extended continuity requirements of independent fields at micro- and macro-level, we discretize both scales via isogeometric analysis (IGA). As a result, we obtain an IGA2-method that is conceptually similar to the well-known FE2-method. We demonstrate the functionality and accuracy of this novel multiscale method by means of a series of multiscale simulations involving different kinds of higher-order continua.
Isa Ducke, Sven Saaler (Hg.): Japan und Korea auf dem Weg in eine gemeinsame Zukunft. Aufgaben und Perspektiven
Creators: name: Köllner, Patrick
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2022

description: ASIEN: The German Journal on Contemporary Asia, Nr. 95 (2005): ASIEN (April)
Table S1 from Sills and gas generation in the Siberian Traps.
Creators: name: Svensen, Henrik H.
name: Frolov, Sergei
name: Akhmanov, Grigorii G.
name: Polozov, Alexander G.
name: Jerram, Dougal A.
name: Shiganova, Olga
name: Melnikov, Nikolay
name: Iyer, Karthik
name: Planke, Sverre
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Total organic carbon (TOC) content in two selected boreholes
Identification of the Extracellular Matrix Binding Sites for Insulin-like Growth Factor-binding Protein 5
Creators: name: Clemmons, David R.
name: Parker, Alex
name: Clarke, Jane Badley
name: Busby Jr., Walker H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Fibroblast extracellular matrix (ECM) contains two forms of insulin-like growth factor-binding proteins (IGFBPs), IGFBP-3 and IGFBP-5. These studies were undertaken to identify the regions within IGFBP-5 that mediate its binding to fibroblast ECM. Synthetic peptides were prepared that were homologous with two regions of basic amino acids within IGFBP-5 (Arg201-Arg218 and Ala131-Thr141). Increasing concentrations of both peptides competed with IGFBP-5 for binding to ECM but the Arg201-Arg218 peptide was more potent. Mutagenesis was used to define the effect of substituting for these basic residues on ECM binding. Substitution for two peptide B residues K134A and R136A reduced binding by 40%. Substitution of a single basic residue within the peptide A region (K211N) reduced binding to ECM by 49%. Substitution for K211N, K134A, and R136A reduced binding by 52%. More extensive substitutions in the peptide A region, e.g. K211N,R214A,K217A,R218N, resulted in a greater (e.g. 88%) decrease. The positional location of basic residues appeared to be more important than the total number of substitutions since the mutant K202N,K206A,R207A had a 79% reduction in ECM binding. Two basic regions of IGFBP-5 contribute to its binding to ECM, but the region containing amino acids 201-218 has a greater contribution. ECM binding is mediated by charged residues and acts to stabilize IGFBP-5 by protecting it from proteolysis.
(2021) Thomas Conlon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Direct Calculation of Ice Homogeneous Nucleation Rate for a Molecular Model of Water
Creators: name: Haji-Akbari, Amir
name: Debenedetti, Pablo G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Ice formation is ubiquitous in nature, with important consequences in a variety of environments, including biological cells, soil, aircraft, transportation infrastructure and atmospheric clouds. However, its intrinsic kinetics and microscopic mechanism are difficult to discern with current experiments. Molecular simulations of ice nucleation are also challenging, and direct rate calculations have only been performed for coarse-grained models of wate. For molecular models, only indirect estimates have been obtained, e.g. by assuming the validity of classical nucleation theory. We use a path sampling approach to perform the first direct rate calculation of homogeneous nucleation of ice in a molecular model of water. We use TIP4P/Ice, the most accurate among existing molecular models for studying ice polymorphs. By using a novel topological approach to distinguish different polymorphs, we are able to identify a freezing mechanism that involves a competition between cubic and hexagonal ice in the early stages of nucleation. In this competition, the cubic polymorph takes over since the addition of new topological structural motifs consistent with cubic ice leads to the formation of more compact crystallites. This is not true for topological hexagonal motifs, which give rise to elongated crystallites that are not able to grow. This leads to transition states that are rich in cubic ice, and not the thermodynamically stable hexagonal polymorph. This mechanism provides a molecular explanation to the earlier experimental and computational observations of the preference for cubic ice in the literature.
description: Main Paper: 10 pages, 6 figures, 1 table, Supplementary Information: 9 pages, 7 figures, 1 table
Insulin-like Growth Factor-I (IGF-I) Regulates IGF-binding Protein-5 Synthesis through Transcriptional Activation of the Gene in Aortic Smooth Muscle Cells
Creators: name: Clemmons, David R.
name: Prevette, Tracy
name: Hawes, Scott B.
name: Duan, Cunming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Previous studies have shown that porcine aortic smooth muscle cells (SMCs) secrete two insulin-like growth factor-binding proteins (IGFBP), IGFBP-2 and -4, and that these IGFBPs modulate IGF-I-stimulated SMC proliferation and migration. In this study we demonstrate that porcine SMCs express IGFBP-5 mRNA and synthesize and secrete the protein. In this cell type, the biosynthesis of IGFBP-5 is up-regulated by IGF-I. This increase in IGFBP-5 synthesis is accompanied by an increase in the steady-state mRNA levels. The induction of IGFBP-5 mRNA by IGF-I is time- and dose-dependent and requires de novo protein synthesis. IGF-II and insulin also increase IGFBP-5 mRNA levels at high doses. An IGF-I analog with normal affinity for the IGF-I receptor but reduced affinity for IGFBPs evokes a similar increase. Another analog that binds to IGFBPs but not to the receptor has no effect, indicating that this effect of IGF-I is mediated through the IGF-I receptor. The IGF-I-induced IGFBP-5 gene expression is cell type-specific because IGF-I had no such effect in other cell types examined. Nuclear run-on assays revealed that IGF-I increased transcription rate of the IGFBP-5 gene, while IGF-I did not change the IGFBP-5 mRNA stability. Furthermore, the IGFBP-5 promoter was 3.5-fold more active in directing expression of the luciferase reporter gene in IGF-I-treated aortic SMCs as compared to control cells, whereas the luciferase activity remained the same in control- and IGF-I-treated fibroblasts. These results suggest that IGF-I up-regulates IGFBP-5 synthesis by transcriptionally activating the IGFBP-5 gene in aortic SMCs.
FLiMS: a Fast Lightweight 2-way Merger for Sorting
Creators: name: Papaphilippou, Philippos
name: Luk, Wayne
name: Brooks, Chris
Publisher: name: arXiv
Year: 2021
Subjects: subject: Hardware Architecture (cs.AR)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: In this paper, we present FLiMS, a highly-efficient and simple parallel algorithm for merging two sorted lists residing in banked and/or wide memory. On FPGAs, its implementation uses fewer hardware resources than the state-of-the-art alternatives, due to the reduced number of comparators and elimination of redundant logic found on prior attempts. In combination with the distributed nature of the selector stage, a higher performance is achieved for the same amount of parallelism or higher. This is useful in many applications such as in parallel merge trees to achieve high-throughput sorting, where the resource utilisation of the merger is critical for building large trees and internalising the workload for fast computation. Also presented are efficient variations of FLiMS for optimizing throughput for skewed datasets, achieving stable sorting or using fewer dequeue signals. Additionally, FLiMS is shown to perform well as conventional software on modern CPUs supporting single-instruction multiple-data (SIMD) instructions, surpassing the performance of some standard libraries for sorting.
description: Accepted for publication in the IEEE Transactions on Computers. Extension of the similarly-named FPT 2018 paper, with additional functionality variations, comparisons and experiments
The American Soldier in World War II: Attitudes of Troops in Alaska--Form A & B
Creators: name: Research Branch, Information
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Rank in military; entered military by draft/volunteered/national guard; length of time in army; length of time stationed in Alaska; state in which respondent spend last five years of civilian life; branch of army; good/bad time while in military; worried/upset while in military; low/high spirits while in military; worthwhile being in military; military occupation; good chance to show best in occupation; soldier v.s. working a war job; overseas combat v.s. overseas non-combat duty v.s. US duty; combat experience; most dangerous country to fight; respondent's health; climate/weather effects health; importance of outfit in war; importance of military occupation in war; importance of Alaska in war effort; officer/enlisted men relations; pride in company; cooperation in company; impression of men in company; AWOL soldiers; military training; satisfaction in army; military equipment; orientation meetings; source of news; knowledge of recent news events; furlough; rotation to Alaska; correspondence/self-taught courses; church attendance; religion; promotions in company; rather fight Japan or Germany in war; worth fighting war; effort in beating Germany/Japan in war; another war in 25 years; US better/worse place after war; US/foreign country relations; adjustment to army life.
Black hole radiation in the presence of a universal horizon
Creators: name: Michel, Florent
name: Parentani, Renaud
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In Hořava and Einstein-Æther theories of modified gravity, in spite of the violation of Lorentz invariance, spherically-symmetric stationary black hole solutions possess an inner universal horizon which separates field configurations into two disconnected classes. We compute the late time radiation emitted by a dispersive field propagating in such backgrounds. We fix the initial conditions on stationary modes by considering a regular collapsing geometry, and imposing that the state inside the infalling shell is vacuum. We find that the mode pasting across the shell is adiabatic at late time (large inside frequencies). This implies that large black holes emit a thermal flux with a temperature fixed by the surface gravity of the Killing horizon. In turn, this suggests that the universal horizon should play no role in the thermodynamical properties of these black holes.
description: 19 pages, 9 figures, final version published in Physical Review D
Additional file 1 of A realist evaluation of a home-based end of life care service for children and families: what works, for whom, how, in what circumstances and why?
Creators: name: Malcolm, Cari
name: Knighting, Katherine
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 1. Supplementary File 1 - RAMESES II reporting standards for realist evaluations.
Table S1 from Sills and gas generation in the Siberian Traps
Creators: name: Svensen, Henrik H.
name: Frolov, Sergei
name: Akhmanov, Grigorii G.
name: Polozov, Alexander G.
name: Jerram, Dougal A.
name: Shiganova, Olga
name: Melnikov, Nikolay
name: Iyer, Karthik
name: Planke, Sverre
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Total organic carbon (TOC) content in two selected boreholes
Design of Highly Efficient Hybrid Si-Au Taper for Dielectric Strip Waveguide to Plasmonic Slot Waveguide Mode Converter
Creators: name: Chen, Chin-Ta
name: Xu, Xiaochuan
name: Hosseini, Amir
name: Pan, Zeyu
name: Subbaraman, Harish
name: Zhang, Xingyu
name: Chen, Ray T.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In this paper, we design a dielectric-to-plasmonic slot waveguide mode converter based on the hybrid silicon-gold taper. The effects of mode matching, the effective index matching, and the metallic absorption loss on the conversion efficiency are studied. Consequently, a metallic taper-funnel coupler with an overall length of 1.7um is designed to achieve a very high conversion efficiency of 93.3% at 1550 nm. The configuration limitations for not allowing this mode converter to achieve a 100% conversion efficiency are also investigated. Such a high-efficiency converter can provide practical routes to realize ultracompact integrated circuits.
description: 6 pages, 7 figures
Figure S1 from Sills and gas generation in the Siberian Traps
Creators: name: Svensen, Henrik H.
name: Frolov, Sergei
name: Akhmanov, Grigorii G.
name: Polozov, Alexander G.
name: Jerram, Dougal A.
name: Shiganova, Olga
name: Melnikov, Nikolay
name: Iyer, Karthik
name: Planke, Sverre
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences

description: Additional logs from the Tunguska Basin in East Siberia.
(2017) John James Conlon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(2018) Peter Henry Conlon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(2013) Mary [Robinson]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The American Soldier in World War II: Attitudes Toward Demobilization
Creators: name: Research Branch, Information
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Rank in military; branch of army; length of time in military; entered military by draft/volunteered/national guard; overseas duty in military; combat experience while in army; releasing soldiers from army; soldiers chosen to have overseas duty; releasing soldiers with families first; releasing soldiers with important skills first; releasing soldiers with combat experience first.
Intrinsic Activity and Stability of Bifunctional Human UMP Synthase and Its Two Separate Catalytic Domains, Orotate Phosphoribosyltransferase and Orotidine-5′-phosphate Decarboxylase
Creators: name: Jones, Mary Ellen
name: Pasek, Daniel A.
name: Traut, Thomas W.
name: Han, Byoung Don
name: Yablonski, Michael J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Human UMP synthase is a bifunctional protein containing two separate catalytic domains, orotate phosphoribosyltransferase (EC 2.4.2.10) and orotidine-5'-phosphate decarboxylase (EC 4.1.1.23). These studies address the question of why the last two reactions in pyrimidine nucleotide synthesis are catalyzed by a bifunctional enzyme in mammalian cells, but by two separate enzymes in microorganisms. From existing data on subunit associations of the respective enzymes and calculations showing the molar concentration of enzyme to be far lower in mammalian cells than in microorganisms, we hypothesize that the covalent union in UMP synthase stabilizes the domains containing the respective catalytic centers. Evidence supporting this hypothesis comes from studies of stability of enzyme activity in vitro, at physiological concentrations, of UMP synthase, the two isolated catalytic domains prepared by site-directed mutagenesis of UMP synthase, and the yeast ODCase. The two engineered domains have activities very similar to the native UMP synthase, but unlike the bifunctional protein, the domains are quite unstable under conditions promoting the dissociated monomer.
Spark Optimization of Linear Codes for Reliable Data Delivery by Relay Drones
Creators: name: Chatzigeorgiou, Ioannis
Publisher: name: arXiv
Year: 2021
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: Data gathering operations in remote locations often rely on relay drones, which collect, store and deliver transmitted information to a ground control station. The probability of the ground control station successfully reconstructing the gathered data can be increased if random linear coding (RLC) is used, especially when feedback channels between the drones and the transmitter are not available. RLC decoding can be complemented by partial packet recovery (PPR), which utilizes sparse recovery principles to repair erroneously received data before RLC decoding takes place. We explain that the spark of the transpose of the parity-check matrix of the linear code, that is, the smallest number of linearly-dependent columns of the matrix, influences the effectiveness of PPR. We formulate a spark optimization problem and obtain code designs that achieve a gain over PPR-assisted RLC, in terms of the probability that the ground control station will decode the delivered data.
description: 6 pages, 4 figures, 1 table. To be published in the proceedings of the 2021 IEEE Military Communications Conference (MILCOM 2021)
Isoform Diversity of Dystrobrevin, the Murine 87-kDa Postsynaptic Protein
Creators: name: Davies, Kay E.
name: Froehner, Stanley C.
name: Peters, Matthew F.
name: Nawrotzki, Ralph
name: Blake, Derek J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Dystrophin-related and -associated proteins are important in the formation and maintenance of the mammalian neuromuscular junction. We have characterized mouse cDNA clones encoding isoforms of the dystrophin-homologous 87-kDa postsynaptic protein, dystrobrevin. In Torpedo, the 87-kDa protein is multiply phosphorylated and closely associated with proteins in the postsynaptic cytoskeleton, including the acetylcholine receptor. In contrast to Torpedo, where only a single transcript is seen, the mouse expresses several mRNAs encoding different isoforms. A 6.0-kilobase transcript in brain encodes a 78-kDa protein (dystrobrevin-1) that is very similar to the Torpedo sequence. A second transcript encodes a 59-kDa protein (dystrobrevin-2) that has a different C terminus, lacking the putative tyrosine kinase substrate domain. In skeletal and cardiac muscle, transcripts of 1.7 and 3.3/3.5 kilobases predominate and encode additional isoforms. Alternative splicing within the coding region and differential usage of untranslated regions produce additional variation. Multiple dystrobrevin-immunoreactive proteins copurify with syntrophin from mouse tissues. In skeletal muscle, dystrobrevin immunoreactivity is restricted to the neuromuscular junction and sarcolemma. The occurrence of many dystrobrevin isoforms is significant because alternative splicing and phosphorylation often have profound effects upon the biological activity of synaptic proteins.
Supplementary methods and results from Within-shoal phenotypic homogeneity affects shoaling preference in a killifish.
Creators: name: Cattelan, Silvia
name: Griggio, Matteo
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Supplementary information on the experimental procedure, apparatus and behaviour of stimulus shoals
Sawada, Seiji, Tomiyasu, Hideo und Masamitsu Nozawa (Hrsg.): Sanierung und Erneuerung von Großwohnsiedlungen. Lösungsansatz Offenes Bauen Refurbishment and Renovation of Large Housing Estates. The Open Building Solution. Report from Study Group in Tokyo
Creators: name: Flüchter, Winfried
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2022

description: ASIEN: The German Journal on Contemporary Asia, Nr. 95 (2005): ASIEN (April)
Additional file 1 of Six-month outcomes of the HOPE smartphone application designed to support treatment with medications for opioid use disorder and piloted during an early statewide COVID-19 lockdown
Creators: name: Hodges, Jacqueline
name: Waselewski, Marika
name: Harrington, William
name: Franklin, Taylor
name: Schorling, Kelly
name: Huynh, Jacqueline
name: Tabackman, Alexa
name: Otero, Kori
name: Ingersoll, Karen
name: Tiouririne, Nassima Ait-Daoud
name: Flickinger, Tabor
name: Dillingham, Rebecca
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. List of HOPE platform features and functions. Table describing features of HOPE platform.
(2015) Hugh Conlon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Supplementary methods and results from Within-shoal phenotypic homogeneity affects shoaling preference in a killifish
Creators: name: Cattelan, Silvia
name: Griggio, Matteo
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Supplementary information on the experimental procedure, apparatus and behaviour of stimulus shoals
Isolation of a NCK-associated Kinase, PRK2, an SH3-binding Protein and Potential Effector of Rho Protein Signaling
Creators: name: Copeland, Neal G.
name: Gilbert, Debra J.
name: Mickelson-Young, Leigh A.
name: Der, Channing J.
name: Westwick, John K.
name: Sparks, Andrew B.
name: Lambert, Que T.
name: Jenkins, Nancy A.
name: Quilliam, Lawrence A.
name: Kay, Brian K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: The NCK adapter protein is comprised of three consecutive Src homology 3 (SH3) protein-protein interaction domains and a C-terminal SH2 domain. Although the association of NCK with activated receptor protein-tyrosine kinases, via its SH2 domain, implicates NCK as a mediator of growth factor-induced signal transduction, little is known about the pathway(s) downstream of NCK recruitment. To identify potential downstream effectors of NCK we screened a bacterial expression library to isolate proteins that bind its SH3 domains. Two molecules were isolated, the Wiskott-Aldrich syndrome protein (WASP, a putative CDC42 effector) and a serine/threonine protein kinase (PRK2, closely related to the putative Rho effector PKN). Using interspecific backcross analysis the Prk2 gene was mapped to mouse chromosome 3. Unlike WASP, which bound the SH3 domains of several signaling proteins, PRK2 specifically bound to the middle SH3 domain of NCK and (weakly) that of phospholipase Cgamma. PRK2 also specifically bound to Rho in a GTP-dependent manner and cooperated with Rho family proteins to induce transcriptional activation via the serum response factor. These data suggest that PRK2 may coordinately mediate signal transduction from activated receptor protein-tyrosine kinases and Rho and that NCK may function as an adapter to connect receptor-mediated events to Rho protein signaling.
Hans-Wilm Schütte: Die Asienwissenschaften in Deutschland. Geschichte, Stand und Perspektiven
Creators: name: Roetz, Heiner
name: Oesterheld, Joachim
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2022

description: ASIEN: The German Journal on Contemporary Asia, Nr. 95 (2005): ASIEN (April)
(2016) Deborah Shepherd
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Livingston et al supplemental material from Widespread use of emersion and cutaneous ammonia excretion in Aplocheiloid killifishes.
Creators: name: Livingston, Michael D.
name: Bhargav, Vikram V.
name: Turko, Andy J.
name: Wilson, Jonathan M.
name: Wright, Patricia A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Physiology
subject: FOS: Biological sciences

description: Figures S1-S3, Table S1, and supplemental methods
Livingston et al supplemental material from Widespread use of emersion and cutaneous ammonia excretion in Aplocheiloid killifishes
Creators: name: Livingston, Michael D.
name: Bhargav, Vikram V.
name: Turko, Andy J.
name: Wilson, Jonathan M.
name: Wright, Patricia A.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Physiology
subject: FOS: Biological sciences

description: Figures S1-S3, Table S1, and supplemental methods
The $\hbar\rightarrow 0$ Limit of the Entanglement Entropy
Creators: name: Mussardo, Giuseppe
name: Viti, Jacopo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Entangled quantum states share properties that do not have classical analogs, in particular, they show correlations that can violate Bell inequalities. It is therefore an interesting question to see what happens to entanglement measures -- such as the entanglement entropy for a pure state -- taking the semi-classical limit, where the naive expectation is that they may become singular or zero. This conclusion is however incorrect. In this paper, we determine the $\hbar\rightarrow 0$ limit of the bipartite entanglement entropy for a one-dimensional system of $N$ quantum particles in an external potential and we explicitly show that this limit is finite. Moreover, if the particles are fermionic, we show that the $\hbar\rightarrow 0$ limit of the bipartite entanglement entropy coincides with the Shannon entropy of $N$ bits.
description: 11 pages, 1 figure. Published version: some references added, discussion slightly improved
Supplementary Figure 1 from Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds.
Creators: name: Downing, Philip A.
name: Griffin, Ashleigh S.
name: Cornwallis, Charlie K.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The evolution of helping behaviour in species that breed cooperatively in family groups is typically attributed to kin selection alone. However, in many species, helpers go on to inherit breeding positions in their natal groups, but the extent to which this contributes to selection for helping is unclear, as the future reproductive success of helpers is often unknown. To quantify the role of future reproduction in the evolution of helping, we compared the helping effort of female and male retained offspring across cooperative birds. The kin selected benefits of helping are equivalent between female and male helpers—they are equally related to the younger siblings they help raise—but the future reproductive benefits of helping differ because of sex differences in the likelihood of breeding in the natal group. We found that the sex which is more likely to breed in its natal group invests more in helping, suggesting that in addition to kin selection, helping in family groups is shaped by future reproduction.
Lfc and Lsc Oncoproteins Represent Two New Guanine Nucleotide Exchange Factors for the Rho GTP-binding Protein
Creators: name: Cerione, Richard A.
name: Glaven, Judith A.
name: Nomanbhoy, Tyzoon
name: Whitehead, Ian P.
name: Kay, Robert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Lfc and Lsc are two recently identified oncoproteins that contain a Dbl homology domain in tandem with a pleckstrin homology domain and thus share sequence similarity with a number of other growth regulatory proteins including Dbl, Tiam-1, and Lbc. We show here that Lfc and Lsc, like their closest relative Lbc, are highly specific guanine nucleotide exchange factors (GEFs) for Rho, causing a >10-fold stimulation of [3H]GDP dissociation from Rho and a marked stimulation of GDP-[35S]GTPgammas (guanosine 5'-O-(3-thiotriphosphate) exchange. All three proteins (Lbc, Lfc, and Lsc) are able to act catalytically in stimulating the guanine nucleotide exchange activity, such that a single molecule of each of these oncoproteins can activate a number of molecules of Rho. Neither Lfc nor Lsc shows any ability to stimulate GDP dissociation from other related GTP-binding proteins such as Rac, Cdc42, or Ras. Thus Lbc, Lfc, and Lsc appear to represent a subgroup of Dbl-related proteins that function as highly specific GEFs toward Rho and can be distinguished from Dbl, Ost, and Dbs which are less specific and show GEF activity toward both Rho and Cdc42. Consistent with these results, Lbc, Lfc, and Lsc each form tight complexes with the guanine nucleotide-depleted form of Rho and bind weakly to the GDP- and GTPgammaS-bound states. None of these oncoproteins are able to form complexes with Cdc42 or Ras. However, Lfc (but not Lbc nor Lsc) can bind to Rac, and this binding occurs equally well when Rac is nucleotide-depleted or is in the GDP- or GTPgammaS-bound state. These findings raise the possibility that in addition to acting directly as a GEF for Rho, Lfc may play other roles that influence the signaling activities of Rac and/or coordinate the activities of the Rac and Rho proteins.
Additional file 2 of Six-month outcomes of the HOPE smartphone application designed to support treatment with medications for opioid use disorder and piloted during an early statewide COVID-19 lockdown
Creators: name: Hodges, Jacqueline
name: Waselewski, Marika
name: Harrington, William
name: Franklin, Taylor
name: Schorling, Kelly
name: Huynh, Jacqueline
name: Tabackman, Alexa
name: Otero, Kori
name: Ingersoll, Karen
name: Tiouririne, Nassima Ait-Daoud
name: Flickinger, Tabor
name: Dillingham, Rebecca
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. HOPE app activity. Summary of participant activity on platform during 6-month post-enrollment period.
Supplementary Figure 1 from Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds
Creators: name: Downing, Philip A.
name: Griffin, Ashleigh S.
name: Cornwallis, Charlie K.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The evolution of helping behaviour in species that breed cooperatively in family groups is typically attributed to kin selection alone. However, in many species, helpers go on to inherit breeding positions in their natal groups, but the extent to which this contributes to selection for helping is unclear, as the future reproductive success of helpers is often unknown. To quantify the role of future reproduction in the evolution of helping, we compared the helping effort of female and male retained offspring across cooperative birds. The kin selected benefits of helping are equivalent between female and male helpers—they are equally related to the younger siblings they help raise—but the future reproductive benefits of helping differ because of sex differences in the likelihood of breeding in the natal group. We found that the sex which is more likely to breed in its natal group invests more in helping, suggesting that in addition to kin selection, helping in family groups is shaped by future reproduction.
Wissenschaftliche Jahrestagung des Arbeitskreises Sozialwissenschaftliche Chinaforschung (ASC) in der DGA
Creators: name: Fischer, Doris
name: Senz, Anja
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2022

description: ASIEN: The German Journal on Contemporary Asia, Nr. 95 (2005): ASIEN (April)
Supplementary Figure 2 from Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds.
Creators: name: Downing, Philip A.
name: Griffin, Ashleigh S.
name: Cornwallis, Charlie K.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The evolution of helping behaviour in species that breed cooperatively in family groups is typically attributed to kin selection alone. However, in many species, helpers go on to inherit breeding positions in their natal groups, but the extent to which this contributes to selection for helping is unclear, as the future reproductive success of helpers is often unknown. To quantify the role of future reproduction in the evolution of helping, we compared the helping effort of female and male retained offspring across cooperative birds. The kin selected benefits of helping are equivalent between female and male helpers—they are equally related to the younger siblings they help raise—but the future reproductive benefits of helping differ because of sex differences in the likelihood of breeding in the natal group. We found that the sex which is more likely to breed in its natal group invests more in helping, suggesting that in addition to kin selection, helping in family groups is shaped by future reproduction.
(2014) Mary Robinson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The American Soldier in World War II: Attitudes Toward Venereal Disease and Malaria
Creators: name: Research Branch, Information
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: Rank in military; state in which respondent spend last five years of civilian life; entered military by draft/volunteered/national guard; length of time in China-Burma-India (CBI) theater; length of time at present station; branch of army; low/high spirits while in military; soldier v.s. working a war job; off-duty activities; recreation and entertainment; knowledge of venereal diseases and sexual problems; sexual intercourse while in CBI; consumption of alcohol while in CBI; preventing venereal diseases; shows attended and liked by respondent; Malaria; Atabrine medication for Malaria; mosquito repellents; screened in sleeping quarters.
Barjols, place de la Rouguière, au milieu des spectateurs de la fête provençale, Maguy Pichonnet-Andral près des appareils d'enregistrement sonore
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
Elektronisch regieren in der Löwenstadt. Internetressourcen aus und über Singapur (I)
Creators: name: Wischermann, Jörg
name: Sander, Ingvar
name: Förster, Renate
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2022

description: ASIEN: The German Journal on Contemporary Asia, Nr. 95 (2005): ASIEN (April)
Supplementary Figure 2 from Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds
Creators: name: Downing, Philip A.
name: Griffin, Ashleigh S.
name: Cornwallis, Charlie K.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: The evolution of helping behaviour in species that breed cooperatively in family groups is typically attributed to kin selection alone. However, in many species, helpers go on to inherit breeding positions in their natal groups, but the extent to which this contributes to selection for helping is unclear, as the future reproductive success of helpers is often unknown. To quantify the role of future reproduction in the evolution of helping, we compared the helping effort of female and male retained offspring across cooperative birds. The kin selected benefits of helping are equivalent between female and male helpers—they are equally related to the younger siblings they help raise—but the future reproductive benefits of helping differ because of sex differences in the likelihood of breeding in the natal group. We found that the sex which is more likely to breed in its natal group invests more in helping, suggesting that in addition to kin selection, helping in family groups is shaped by future reproduction.
Additional file 3 of Association of body mass index and COPD exacerbation among patients with chronic bronchitis
Creators: name: Shin, Sun Hye
name: Kwon, Sung Ok
name: Kim, Victor
name: Silverman, Edwin Kepner
name: Kim, Tae-Hyung
name: Kim, Deog Kyeom
name: Hwang, Yong Il
name: Yoo, Kwang Ha
name: Kim, Woo Jin
name: Park, Hye Yun
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 3: Table S1. Incidence and the risk ratios of COPD exacerbation (≥ 1 moderate or ≥ 1 severe) during 1-year follow-up according to the presence of chronic bronchitis and BMI categories (using cut-off 23 kg/m2) in 1264 patients from the KOCOSS.
(2010) William James Stead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Becoming A Member of A Ward Nursing Community of Practice: Negotiating Participation Space
Creators: name: Chen, Xiaorong Mary
name: Newman, Mark
name: Park, Sophie
Publisher: name: Singapore Institute of Technology
Year: 2022
Subjects: Nursing not elsewhere classified
Nursing workforce

description: This research aimed to find out how newly graduated nurses, also known as novices, participate in clinical practice in their first year. Current literature adopts a fixed model of a competent identity, judging an individual nurse either competent or not without the consideration of the working context. We aimed to find out what really happens during their transition. The workplace is a shared space which all nurses have to navigate daily. This space consists a fabric of mental and physical factors such as people, their interactions and the perceived power positions among them. Just like how drivers do at any traffic intersection, nurses have to find their passage through this shared space with other healthcare workers. The passage each nurse negotiated is his/her Participation Space. There are various factors they need to take into consideration.We identified Prized Tasks, Relational Position and Contextual Dimensions.