cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Mg I b triplet and the 4571 Å line as diagnostics of stellar chromospheric activity
Creators: name: Sasso, C.
name: Andretta, V.
name: Terranegra, L.
name: Gomez, M. T.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context. The Mg I 4571 Å line and the b triplet are denoted in the literature as diagnostics of solar and stellar activity since their formation is in the low chromosphere. Aims. To investigate the potential of these four spectral lines as diagnostics of chromospheric activity in solar-like stars, studying the dependence of the intensity of these lines from local atmospheric changes by varying atmospheric models and stellar parameters. Methods. Starting with Next-Gen photospheric models, we build a grid of atmospheric models including photosphere, chromosphere and transition region and solve the radiative transfer to obtain synthetic profiles to compare with observed spectra of main-sequence, solar like stars with effective temperatures in the range 4800-6400 K, solar gravity and solar metallicity. Results. We find that the Mg I 4571 Å line is significantly sensitive to local changes in the atmospheric model around the minimum temperature. Instead, the lines of the b triplet do not show significant responses to changes on the local atmospheric structure.
description: Accepted for publication in A&A on Jun 12th 2017
Ground state cooling in a bad cavity
Creators: name: Zippilli, Stefano
name: Morigi, Giovanna
name: Schleich, Wolfgang P.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the mechanical effects of light on an atom trapped in a harmonic potential when an atomic dipole transition is driven by a laser and it is strongly coupled to a mode of an optical resonator. We investigate the cooling dynamics in the bad cavity limit, focussing on the case in which the effective transition linewidth is smaller than the trap frequency, hence when sideband cooling could be implemented. We show that quantum correlations between the mechanical actions of laser and cavity field can lead to an enhancement of the cooling efficiency with respect to sideband cooling. Such interference effects are found when the resonator losses prevail over spontaneous decay and over the rates of the coherent processes characterizing the dynamics.
description: 6 pages, 5 figures; J. Mod. Opt. (2007)
ИСПОЛЬЗОВАНИЕ МОБИЛЬНЫХ ПРИЛОЖЕНИЙ ДЛЯ БОРЬБЫ С ОТХОДАМИ И УЛУЧШЕНИЯ ЭКОЛОГИЧЕСКОЙ ОБСТАНОВКИ НА ТЕРРИТОРИИ РОССИИ
Creators: name: Пермяков Василий Алексеевич
name: Субботина Юлия Алексеевна
name: Черемных Никита Константинович
name: Иванова Екатерина Андреевна
Publisher: name: Colloquium-journal
Year: 2019
Subjects: отходы
экологическая обстановка
безопасность жизнедеятельности
окружа-ющая среда
население
информирование
экологическое приложения
вторсырье
переработка отходов
сортировка
отношение
современные технологии

description: В статье рассмотрены положительные стороны использования мобильных приложений в рамках борьбы с отходами и улучшения экологической обстановки. Актуальность темы обуславливается высо-кой степенью социальной напряженности, связанной с проблемой отходов, распространения мусорных полигонов и общим ухудшением состояния окружающей среды, что негативно отражается на здоровье граждан. В статье рассматриваются примеры мобильных приложений с эко-направленностью, а также определяются возможные направления использования для повышения экологической сознатель-ности граждан и изменения экологического фона. Также в статье определяется необходимость все-стороннего продвижения политики эко-сознательности на государственном уровне
К ВОПРОСУ ОБ ОРОНИМАХ В РУССКОМ, БАШКИРСКОМ И КИТАЙСКОМ ЯЗЫКАХ
Creators: name: Абдуллина Л. Б.
name: Султанбаева Х. В.
name: Федорова А. П.
Publisher: name: Colloquium-journal
Year: 2019
Subjects: оронимы
оронимия
башкирский язык
русский язык
китайский язык.

description: Оронимия русского, башкирского и китайского языков весьма специфична, каждая имеет свой национальный и исторический колорит. Вместе с тем имеются и объединяющие факторы, которые на сегодняшний день остаются недостатоно изученными. Следует также отметить, что в настоящее время, на наш взгляд, проблемы оронимии изучены меньше, чем гидронимия и ойконимия. Все эти факторы свидетельствуют об актуальности изучения оронимимов русского, башкирского и китайского языков, выявить их специфические и общие признаки. Изучение оронимов дает полное представление о топонимике различных культур и национальностей в целом. Благодаря изучению оронимов можно точно проследить историю происхождения того или иного географического названия в данных языках. Сопо-ставительное исследование оронимов в русском, китайском и башкирском языках дает возможность выявить сходные и отличительные признаки в способах образования их названий в изучаемых языках
Automatic Brain Tumor Segmentation using Cascaded Anisotropic Convolutional Neural Networks
Creators: name: Wang, Guotai
name: Li, Wenqi
name: Ourselin, Sebastien
name: Vercauteren, Tom
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: A cascade of fully convolutional neural networks is proposed to segment multi-modal Magnetic Resonance (MR) images with brain tumor into background and three hierarchical regions: whole tumor, tumor core and enhancing tumor core. The cascade is designed to decompose the multi-class segmentation problem into a sequence of three binary segmentation problems according to the subregion hierarchy. The whole tumor is segmented in the first step and the bounding box of the result is used for the tumor core segmentation in the second step. The enhancing tumor core is then segmented based on the bounding box of the tumor core segmentation result. Our networks consist of multiple layers of anisotropic and dilated convolution filters, and they are combined with multi-view fusion to reduce false positives. Residual connections and multi-scale predictions are employed in these networks to boost the segmentation performance. Experiments with BraTS 2017 validation set show that the proposed method achieved average Dice scores of 0.7859, 0.9050, 0.8378 for enhancing tumor core, whole tumor and tumor core, respectively. The corresponding values for BraTS 2017 testing set were 0.7831, 0.8739, and 0.7748, respectively.
description: 12 pages, 5 figures. MICCAI Brats Challenge 2017
ИСТОРИОГРАФИЯ ПРЕССЫ ПОЛИТИЧЕСКИХ ПАРТИЙ РОССИИ НАЧАЛА ХХ ВЕКА
Creators: name: Боброва Д. А.
Publisher: name: Colloquium-journal
Year: 2019
Subjects: регион
печать
история журналистики
типология
пресса политических партий
система журналистики
системоформирующие факторы

description: Этот научный обзор посвящен многогранной исследовательской деятельности профессора Южно-го федерального университета Евгения Валерьевича Ахмадулина в год его 75-летия. Его труды дали толчок к образованию исследовательских школ журналистского регионоведения на Юге России и изуче-нию партийной прессы России начала ХХ века.
ПУТИ МОДЕРНИЗАЦИИ РЕГИОНАЛЬНОЙ СИСТЕМЫ ОБРАЗОВАНИЯ В СОВРЕМЕННЫХ УСЛОВИЯХ НА ПРИМЕРЕ РЕСПУБЛИКИ КРЫМ
Creators: name: Ягнич А. Я.
Publisher: name: Colloquium-journal
Year: 2019
Subjects: Модернизация
инновация
система образования
образовательные программы
качество образования.

description: В статье говорится о модернизации образования в современных условиях, в частности, на примере Республики Крым. В современном мире образование нужно каждому человеку. Целью модернизации яв-ляется развитие конкурентоспособной системы образования, соответствие экономическим и социаль-ным запросам, потребностям страны, общества и государства. Требования к образованному человеку на сегодняшний день очень высоки, поэтому система образования должна готовить людей к тому, чтобы они не только смогли адаптироваться к жизни в социуме, но и сумели создать все необходимые условия для этого общества.
Supplementary tables 1-2 from Evolution of genomic variation in the burrowing owl in response to recent colonization of urban areas
Creators: name: Mueller, Jakob C.
name: Kuhl, Heiner
name: Boerno, Stefan
name: Tella, Jose L.
name: Carrete, Martina
name: Kempenaers, Bart
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60408 Genomics

description: FST values; results of RDA and AMOVA models
P-vortices and Drama of Gribov Copies
Creators: name: Bornyakov, V. G.
name: Komarov, D. A.
name: Polikarpov, M. I.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present results of the careful study of the Gribov copies problem in SU(2) lattice gauge theory for the direct maximal center projection widely used in confinement studies. Applying simulated annealing algorithm we demonstrate that this problem is more severe than it was thought before. The projected (gauge noninvariant) string tension is not in the agreement with the physical string tension. We do not find any indications that P-vortices reproduce the full SU(2) string tension neither in the infinite volume limit nor in the continuum limit.
description: 16 pages, 7 figures, Latex2e, typos corrected
Anisotropic emission of neutrino and gravitational-wave signals from rapidly rotating core-collapse supernovae
Creators: name: Takiwaki, Tomoya
name: Kotake, Kei
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present analysis of neutrino and GW signals based on three-dimensional (3D) core-collapse supernova simulations of a rapidly rotating 27 $M_{\odot}$ star. We find a new neutrino signature that is produced by a lighthouse effect where the spinning of strong neutrino emission regions around the rotational axis leads to quasi-periodic modulation in the neutrino signal. Depending on the observer's viewing angle, the time modulation will be clearly detectable in IceCube and the future Hyper-Kamiokande. The GW emission is also anisotropic where the GW signal is emitted, as previously identified, most strongly toward the equator at rotating core-collapse and bounce, and the non-axisymmetric instabilities in the postbounce phase lead to stronger GW emission toward the spin axis. We show that these GW signals can be a target of LIGO-class detectors for a Galactic event. The origin of the postbounce GW emission naturally explains why the peak GW frequency is about twice of the neutrino modulation frequency. We point out that the simultaneous detection of the rotation-induced neutrino and GW signatures could provide a smoking-gun signature of a rapidly rotating proto-neutron star at the birth.
description: 5 pages, 4 figures, accepted for publication in MNRAS Letters
Probing the inner 200 AU of low-mass protostars with the Submillimeter Array: Dust and organic molecules in NGC1333-IRAS2A
Creators: name: Jorgensen, J. K.
name: Bourke, T. L.
name: Myers, P. C.
name: Schoeier, F. L.
name: van Dishoeck, E. F.
name: Wilner, D. J.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Submillimeter Array has opened a new window to study the innermost warm and dense regions of the envelopes and disks around deeply embedded protostars. This paper presents high-angular resolution (< 2'') submillimeter observations of the class 0 young stellar object NGC1333-IRAS2A. Dust continuum emission and lines of complex organic molecules such as CH3OCH3 and CH3OCHO, high excitation CH3OH transitions, deuterated methanol CH3OD as well as lines of CO, HCN, H13CN, SO and SO2 are detected on < 200 AU scales. The observations are interpreted using detailed radiative transfer models of the physical and chemical structure, consistent with both single-dish and interferometer data. The continuum emission is explained by an extended envelope and a compact but resolved component, presumably a circumstellar disk with a diameter of 200-300 AU and a mass of a few times 0.01-0.1 M_sun. If related to the rotation of the envelope, then the size of this disk suggests a centrifugal barrier of 200-300 AU, which implies that the temperature in the envelope does not increase above 100 K. Its large size also suggests that the build-up of disks proceeds rapidly throughout the early protostellar stages. The smaller (< 100 AU) disks found around other deeply embedded protostars may be a result of tidal truncation. The high-resolution observations of SO can be explained with a simple constant abundance, ~1E-9, constrained through single-dish observations, whereas those of H13CN and the organic species require high abundances, increased by one to two orders of magnitude, or an additional compact source of emission at small scales. The compact molecular emission could originate in a hot core region of the inner envelope, but a more likely reservoir is the circumstellar disk.
description: Accepted for publication in ApJ. 24 pages, 5 figures
REVISITING UP-FRONT CHEMOTHERAPY IN EGFR-MUTATED NON–SMALL-CELL LUNG CANCER
Creators: name: Tillyashaikhov Mirzagoleb Nigmatovich
Publisher: name: Colloquium-journal
Year: 2019
Subjects: lung cancer
chemotherapy
EGFR

description: In this article, the authors present data on revision of up-front chemotherapy in EGFR-muted non-small-cell lung cancer (NSCLC).
title: Active and Inactive Metabolic Pathways in Tumor Spheroids: Determination by GC-MS
Creators: name: Hunnewell, Michael
name: Forbes, Neil S.
Publisher: name: University of Massachusetts Amherst
Year: 2010
Subjects: subject: tumor metabolism
subject: GC-MS
subject: spheroids
subject: pentose phosphate pathway
subject: glutaminolysis

description: Active metabolic pathways in three-dimensional cancer-cell cultures are potential chemotherapeutic targets that would be effective throughout tumors. Chaotic vasculature creates cellular regions in tumors with distinct metabolic behavior that are only present in aggregate cell masses. To quantify cancer cell metabolism, transformed mouse fibroblasts were grown as spheroids and fed isotopically labeled culture medium. Metabolite uptake and production rates were measured as functions of time. Gas chromatography - mass spectrometry was used quantify the extent of labeling on amino acids present in cytoplasmic extracts. The labeling pattern identified several active and inactive metabolic pathways: glutaminolysis was found to be active, and malic enzyme and gluconeogenesis were inactive. Transformed cells in spheroids were also found to actively synthesize serine, cysteine, alanine, aspartate, glutamate, and proline; and not synthesize glutamine. The activities of these pathways suggest that cancer cells consume glutamine for biosynthesis and not to provide cellular energy. Determining active metabolic pathways indicates how cells direct carbon flow and may lead to the discovery of novel molecular targets for anti-cancer therapy
DIRECTED RETROVIRAL INFECTION OF NKG2D⁺ MURINE NATURAL KILLER CELLS BY DISPLAYING THE NKG2D LIGAND RAE-1y ON THE VIRUS SURFACE
Creators: name: Sanford, Michael Edwin
Publisher: name: Maryland Shared Open Access Repository
Year: 2008

description: Natural Killer (NK) cells are unique in having the ability to lyse both virally infected cells and tumor cells unrestricted by the major histocompatibility complex (MHC). Given their promise as a therapeutic tool, studying their biology through expressing or repressing genes, would greatly enhance our understanding of these cells and how to use them for clinical purposes. As NK cells are extremely difficult to genetically engineer, the goal of this research project was to create targeted retroviral particles that were capable of increasing transduction of NKG2D⁺ NK cells over nontargeted retroviral particles. To achieve this goal, we generated retroviral particles containing RAE-1y, a ligand for the NK cell receptor NKG213. Using this method, we were able to test the hypothesis that expressing an NK. receptor ligand on retroviral particles would increase the infection efficiency of NKG2D⁺ NK cells. Our results demonstrated that expressing the RAE-1y ligand in the cells producing retroviral particles did not increase the efficiency of NK cell retroviral infection.
Probing Spatial Locality in Ionic Liquids with the Grand Canonical Adaptive Resolution Molecular Dynamics Technique
Creators: name: Jabes, B. Shadrack
name: Krekeler, C.
name: Klein, R.
name: Site, L. Delle
Publisher: name: arXiv
Year: 2017
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We employ the Grand Canonical Adaptive Resolution Molecular Dynamics Technique (GC-AdResS) to test the spatial locality of the 1-ethyl 3-methyl imidazolium chloride liquid. In GC-AdResS atomistic details are kept only in an open sub-region of the system while the environment is treated at coarse-grained level, thus if spatial quantities calculated in such a sub-region agree with the equivalent quantities calculated in a full atomistic simulation then the atomistic degrees of freedom outside the sub-region play a negligible role. The size of the sub-region fixes the degree of spatial locality of a certain quantity. We show that even for sub-regions whose radius corresponds to the size of a few molecules, spatial properties are reasonably {reproduced} thus suggesting a higher degree of spatial locality, a hypothesis put forward also by other {researchers} and that seems to play an important role for the characterization of fundamental properties of a large class of ionic liquids.
description: 25 pages, 18 figures
Quantum Algorithms for Simon's Problem Over General Groups
Creators: name: Alagic, Gorjan
name: Moore, Cristopher
name: Russell, Alexander
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Daniel Simon's 1994 discovery of an efficient quantum algorithm for solving the hidden subgroup problem (HSP) over Z_2^n provided one of the first algebraic problems for which quantum computers are exponentially faster than their classical counterparts. In this paper, we study the generalization of Simon's problem to arbitrary groups. Fixing a finite group G, this is the problem of recovering an involution m = (m_1, ..., m_n) in G^n from an oracle f with the property that f(x) = f(xy) iff y equals m or the identity. In the current parlance, this is the hidden subgroup problem (HSP) over groups of the form G^n, where G is a nonabelian group of constant size, and where the hidden subgroup is either trivial or has order two. Although groups of the form G^n have a simple product structure, they share important representation-theoretic properties with the symmetric groups S_n, where a solution to the HSP would yield a quantum algorithm for Graph Isomorphism. In particular, solving their HSP with the so-called ``standard method'' requires highly entangled measurements on the tensor product of many coset states. Here we give quantum algorithms with time complexity 2^O(sqrt(n log n)) that recover hidden involutions m = (m_1, ..., m_n) in G^n where, as in Simon's problem, each m_i is either the identity or the conjugate of a known element k, and there is a character X of G for which X(k) = -X(1)$. Our approach combines the general idea behind Kuperberg's sieve for dihedral groups with the ``missing harmonic'' approach of Moore and Russell. These are the first nontrivial hidden subgroup algorithms for group families that require highly entangled multiregister Fourier sampling.
OUTCOMES OF TREATMENT REFRACTORY AND RELAPSED HODGKIN LYMPHOMA WITH AUTOLOGOUS STEM CELL TRANSPLANTATION (LITERARY REVIEW)
Creators: name: Кobilov Odiljon Rustamovich
Publisher: name: Colloquium-journal
Year: 2019
Subjects: Hodgkin lymphoma
stem-cell transplantation
high-dose chemotherapy.

description: Hodgkin lymphoma is the most common cancer in children, adolescents, and young adults. Overall survival is approximately 80% to 90%. A subset of these patients has refractory disease or experience disease relapse. Conventional salvage therapies and autologous stem-cell transplantation is usually considered the standard of care for these patients. Our analysis reports outcomes in these patients.
Supplementary figures 1-8 from Evolution of genomic variation in the burrowing owl in response to recent colonization of urban areas
Creators: name: Mueller, Jakob C.
name: Kuhl, Heiner
name: Boerno, Stefan
name: Tella, Jose L.
name: Carrete, Martina
name: Kempenaers, Bart
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60408 Genomics

description: Details of demographic analysis, comparisons of MAF distributions, PCA, and isolation-by-distance analysis
DO SILVER NANOPARTICLES NEED REGULATORY OVERSIGHT?
Creators: name: Santiago, Jo-Ann Collazo
Publisher: name: Maryland Shared Open Access Repository
Year: 2014

description: The liberal use of silver nanoparticles (NPs) in consumer products has created safety concerns in the scientific community. In order to safeguard public welfare regarding exposure to such nanomaterial (NMs), several federal agencies, including the Food and Drug Administration (FDA), are evaluating if the current guidance and regulations for larger, bulk materials are applicable to NMs. A need to ascertain the cause of the presented toxicities of silver NPs has also arisen. This analysis of recent in vitro and in vivo toxicity studies provides insight as to why the lack of standardized protocols for material characterization of silver NPs hinders the evaluation of toxicological data. A review of the selected literature concerning the toxicity of silver NPs resulted in the development of a draft guidance document to aid in future toxicological studies for the safety issues related to this product.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Cart. 188 (11 H 73), f. 0075r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0075r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IV, Archives départementales de la Côte-d'Or, Cart. 188 (11 H 73), f. 0075r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Real Representation in Chiral Gauge Theories on the Lattice
Creators: name: Suzuki, Hiroshi
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The Weyl fermion belonging to the real representation of the gauge group provides a simple illustrative example for Lüscher's gauge-invariant lattice formulation of chiral gauge theories. We can explicitly construct the fermion integration measure globally over the gauge-field configuration space in the arbitrary topological sector; there is no global obstruction corresponding to the Witten anomaly. It is shown that this Weyl formulation is equivalent to a lattice formulation based on the Majorana (left--right-symmetric) fermion, in which the fermion partition function is given by the Pfaffian with a definite sign, up to physically irrelevant contact terms. This observation suggests a natural relative normalization of the fermion measure in different topological sectors for the Weyl fermion belonging to the complex representation.
description: uses phyzzx.tex and phyzzx.plus, 18 pages. The final version to appear in JHEP
D-branes, Monopoles and Nahm Equations
Creators: name: Diaconescu, Duiliu-Emanuel
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the correspondence between IIb solitonic 1-branes and monopoles in the context of the 3-brane realization of $D=4$ $N=4$ super Yang-Mills theory. We show that a bound state of 1-branes stretching between two separated 3-branes exhibits a family of super-symmetric ground states that can be identified with the ADHMN construction of the moduli space of $SU(2)$ monopoles.. This identification is supported by the construction of the monopole gauge field as a space-time coupling in the quantum mechanical effective action of a 1-brane used as a probe. The analysis also reveals an intriguing aspect of the 1-brane theory:the transverse oscillations of the 1-branes in the ground states are described by non-commuting matrix valued fields which develop poles at the boundary. Finally, the construction is generalized to $SU(n)$ monopoles with arbitrary $n>2$.
description: 27 pages, LaTex type, 3 Postscript Figures
Supplementary text S1 from Evolution of genomic variation in the burrowing owl in response to recent colonization of urban areas
Creators: name: Mueller, Jakob C.
name: Kuhl, Heiner
name: Boerno, Stefan
name: Tella, Jose L.
name: Carrete, Martina
name: Kempenaers, Bart
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 60408 Genomics

description: Details of genome assembly and annotation
The effect of atomic response time in the theory of Doppler cooling of trapped ions
Creators: name: Janacek, H.
name: Steane, A. M.
name: Lucas, D. M.
name: Stacey, D. N.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We describe a simple approach to the problem of incorporating the response time of an atom or ion being Doppler-cooled into the theory of the cooling process. The system being cooled does not in general respond instantly to the changing laser frequencies it experiences in its rest frame, and this "dynamic effect" can affect significantly the temperatures attainable. It is particularly important for trapped ions when there is a slow decay out of the cooling cycle requiring the use of a repumping beam. We treat the cases of trapped ions with two and three internal states, then apply the theory to $^{40}{\rm Ca}^+$. For this ion experimental data exist showing the ion to be cold under conditions for which heating is predicted if the dynamic effect is neglected. The present theory accounts for the observed behaviour.
description: 13 pages, 5 figures
A BIOINFORMATICS STUDY OF NUCLEAR INSERTS OF mtDNA (NUMTS) IN CHIMPANZEE (Pan troglodytes) ORIGIN, FRQUENCY AND PHYLOGENETIC COMPARISON.
Creators: name: Satpathy, Bhargavi
Publisher: name: Maryland Shared Open Access Repository
Year: 2005

description: Analysis of mitochondrial DNA (mtDNA) sequence variation has been used for more than two decades as a tool to understand the recent phylogeny of many different species or populations, including chimpanzees (Pan troglodytes). Contemporary taxonomists recognize three subspecies of chimpanzees: Pan troglodytes verus from west Africa, and the poorly differentiated P.t. troglodytes and P.t. .s.chweinfurthii subspecies from central and east Africa, respectively). mtDNA sequences have been used to analyze the geographical patterns of genetic variation among African chimpanzee populations and to infer subspecies identities of captive chimpanzees. However, a potential source of significant and far-reaching problems in the evolutionary analysis of mtDNA arises from the presence of translocated pieces of mtDNA into the nuclear genome. Accurate phylogenetic analysis using mtDNA sequences requires a determination of whether putative mtDNA sequences are contaminated by numts.
Spastin MIT Domain Disease-Associated Mutations Disrupt Lysosomal Function.
Creators: name: Allison, Rachel
name: Edgar, James R
name: Reid, Evan
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Escrt
Hereditary Spastic Paraplegia
Ist1
Endosome Tubule Fission
Chmp1b

description: The hereditary spastic paraplegias (HSPs) are genetic motor neuron diseases characterized by progressive degeneration of corticospinal tract axons. Mutations in SPAST, encoding the microtubule-severing ATPase spastin, are the most common causes of HSP. The broad SPAST mutational spectrum indicates a haploinsufficiency pathogenic mechanism in most cases. Most missense mutations cluster in the ATPase domain, where they disrupt the protein's ability to sever microtubules. However, several putative missense mutations in the protein's microtubule interacting and trafficking (MIT) domain have also been described, but the pathogenicity of these mutations has not been verified with functional studies. Spastin promotes endosomal tubule fission, and defects in this lead to lysosomal enzyme mistrafficking and downstream lysosomal abnormalities. We investigated the function of three disease-associated spastin MIT mutants and found that none was able to promote normal endosomal tubule fission, lysosomal enzyme receptor trafficking, or lysosomal morphology. One of the mutations affected recruitment of spastin to endosomes, a property that requires the canonical function of the MIT domain in binding endosomal sorting complex required for transport (ESCRT)-III proteins. However, the other mutants did not affect spastin's endosomal recruitment, raising the possibility of pathologically important non-canonical roles for the MIT domain. In conclusion, we demonstrate that spastin MIT mutants cause functional abnormalities related to the pathogenesis of HSP. These mutations do not directly affect spastin's microtubule-severing capacity, and so we identify a new molecular pathological mechanism by which spastin mutations may cause disease.
Stellar Cluster Fiducial Sequences with the Advanced Camera for Surveys
Creators: name: Brown, Thomas M.
name: Ferguson, Henry C.
name: Smith, Ed
name: Guhathakurta, Puragra
name: Kimble, Randy A.
name: Sweigart, Allen V.
name: Renzini, Alvio
name: Rich, R. Michael
name: VandenBerg, Don A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present color-magnitude diagrams of five Galactic globular clusters and one Galactic open cluster spanning a wide range of metallicity (-2.1 < [Fe/H] < +0.3), as observed in the F606W (broad V) and F814W (I) bands with the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope. These clusters are part of two large ACS programs measuring the star formation history in the Andromeda halo, tidal stream, and outer disk. In these programs, the clusters serve as empirical isochrones and as calibrators for the transformation of theoretical isochrones to the ACS bandpasses. To make these data more accessible to the community, for each cluster, we provide a ridge line tracing the stars on the main sequence, subgiant branch, and red giant branch, plus the locus of stars on the horizontal branch. In addition, we provide the transformation of the Victoria-Regina isochrones to the ACS bandpasses.
description: 14 pages, 6 black & white figures, 1 color figure, latex. Accepted for publication in The Astronomical Journal. Figures 1-5 have been degraded to meet size restrictions. Smoothing of line art should be disabled in PDF viewers for correct display of figures. Full-resolution version and machine-readable tables available from T.M. Brown (tbrown@stsci.edu)
The SOFA score-development, utility and challenges of accurate assessment in clinical trials.
Creators: name: Lambden, Simon
name: Laterre, Pierre Francois
name: Levy, Mitchell M
name: Francois, Bruno
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Sepsis
Multiple organ failure
Clinical Trials
Surrogate Endpoints
Sofa
Sequential Organ Failure Assessment
Critical Care Trials

description: The Sequential Organ Failure Assessment or SOFA score was developed to assess the acute morbidity of critical illness at a population level and has been widely validated as a tool for this purpose across a range of healthcare settings and environments.In recent years, the SOFA score has become extensively used in a range of other applications. A change in the SOFA score of 2 or more is now a defining characteristic of the sepsis syndrome, and the European Medicines Agency has accepted that a change in the SOFA score is an acceptable surrogate marker of efficacy in exploratory trials of novel therapeutic agents in sepsis. The requirement to detect modest serial changes in a patients' SOFA score therefore means that increased clarity on how the score should be assessed in different circumstances is required.This review explores the development of the SOFA score, its applications and the challenges associated with measurement. In addition, it proposes guidance designed to facilitate the consistent and valid assessment of the score in multicentre sepsis trials involving novel therapeutic agents or interventions.ConclusionThe SOFA score is an increasingly important tool in defining both the clinical condition of the individual patient and the response to therapies in the context of clinical trials. Standardisation between different assessors in widespread centres is key to detecting response to treatment if the SOFA score is to be used as an outcome in sepsis clinical trials.
Phase Transition of Anti-Symmetric Wilson Loops in $\mathcal{N}=4$ SYM
Creators: name: Okuyama, Kazumi
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We will argue that the 1/2 BPS Wilson loops in the anti-symmetric representations in the $\mathcal{N}=4$ super Yang-Mills (SYM) theory exhibit a phase transition at some critical value of the 't Hooft coupling of order $N^2$. In the matrix model computation of Wilson loop expectation values, this phase transition corresponds to the transition between the one-cut phase and the two-cut phase. It turns out that the one-cut phase is smoothly connected to the small 't Hooft coupling regime and the $1/N$ corrections of Wilson loops in this phase can be systematically computed from the topological recursion in the Gaussian matrix model.
description: 22 pages; v2: added reference; v3: version to appear in JHEP
HEIRLOOM: TRANSITORY SCULPTURES REVEAL THE LEGACY OF PREVIOUS GENERATIONS
Creators: name: Schoolfield, Brooke M.
Publisher: name: Maryland Shared Open Access Repository
Year: 2016

description: The grief experienced by the artist during her beloved grandmother's slow decline into the relentless fog of Alzheimer's disease was the origin of this body of work. Because clay can be both a fleeting record and a durable memorial, it was the medium best suited to explore the artist's feelings of loss and commemorate her grandmother's enduring legacy. The artist intends for the unvitrified components of her porcelain sculptures to erode when exposed to wind, rain, and frost, thus illustrating the disease's mental and physical consequences. In contrast, at the core of this body of work are translucent glazed jar forms representing lessons from and pivotal memories of the artist's grandmother. The multilayer, intentionally vulnerable, moulded ceramics demonstrate how, through the partial disintegration of symbolic sculptures, time and loss reveal our heritage from past generations.
title: 01_1995
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
A genomic survey of transposable elements in the choanoflagellate Salpingoeca rosetta reveals selection on codon usage.
Creators: name: Southworth, Jade
name: Grace, C Alastair
name: Marron, Alan O
name: Fatima, Nazeefa
name: Carr, Martin
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Natural selection
Pol
Mutation Pressure
Optimal Codons
Opisthokonta
Tnpase

description: Background:Unicellular species make up the majority of eukaryotic diversity, however most studies on transposable elements (TEs) have centred on multicellular host species. Such studies may have therefore provided a limited picture of how transposable elements evolve across eukaryotes. The choanoflagellates, as the sister group to Metazoa, are an important study group for investigating unicellular to multicellular transitions. A previous survey of the choanoflagellate Monosiga brevicollis revealed the presence of only three families of LTR retrotransposons, all of which appeared to be active. Salpingoeca rosetta is the second choanoflagellate to have its whole genome sequenced and provides further insight into the evolution and population biology of transposable elements in the closest relative of metazoans. Results:Screening the genome revealed the presence of a minimum of 20 TE families. Seven of the annotated families are DNA transposons and the remaining 13 families are LTR retrotransposons. Evidence for two putative non-LTR retrotransposons was also uncovered, but full-length sequences could not be determined. Superfamily phylogenetic trees indicate that vertical inheritance and, in the case of one family, horizontal transfer have been involved in the evolution of the choanoflagellates TEs. Phylogenetic analyses of individual families highlight recent element activity in the genome, however six families did not show evidence of current transposition. The majority of families possess young insertions and the expression levels of TE genes vary by four orders of magnitude across families. In contrast to previous studies on TEs, the families present in S. rosetta show the signature of selection on codon usage, with families favouring codons that are adapted to the host translational machinery. Selection is stronger in LTR retrotransposons than DNA transposons, with highly expressed families showing stronger codon usage bias. Mutation pressure towards guanosine and cytosine also appears to contribute to TE codon usage. Conclusions:S. rosetta increases the known diversity of choanoflagellate TEs and the complement further highlights the role of horizontal gene transfer from prey species in choanoflagellate genome evolution. Unlike previously studied TEs, the S. rosetta families show evidence for selection on their codon usage, which is shown to act via translational efficiency and translational accuracy.
title: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains, f.217
Creators: name: Rouzeau, Benoît
name: Rouzeau, Benoît
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cistercien
subject: cartulaire
subject: LaMOP

description: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains. Numérisation en mode image
description: Relation: https://cisterciensetressources.lamop.fr/
description: Bibliographic citation: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains, f.217, in Projet Cisterciens et Ressources [Ressource en ligne], https://cisterciensetressources.lamop.fr
description: Inventaire des titres de propriété et des actes concernant les droits de l'abbaye de Morimond, Manuscrit n° 1, Bibliothèque municipale de Bourbonne-les-Bains, f. 217
Ionised gas structure of 100 kpc in an over-dense region of the galaxy group COSMOS-Gr30 at z ~ 0.7
Creators: name: Epinat, Benoît
name: Contini, Thierry
name: Finley, Hayley
name: Boogaard, Leindert
name: Guérou, Adrien
name: Brinchmann, Jarle
name: Carton, David
name: Michel-Dansac, Léo
name: Bacon, Roland
name: Cantalupo, Sebastiano
name: Carollo, Marcella
name: Hamer, Stephen
name: Kollatschny, Wolfram
name: Krajnović, Davor
name: Marino, Raffaella Anna
name: Richard, Johan
name: Soucail, Geneviève
name: Weilbacher, Peter M.
name: Wisotzki, Lutz
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report the discovery of a 10^4 kpc^2 gaseous structure detected in [OII] in an over-dense region of the COSMOS-Gr30 galaxy group at z~0.725 thanks to deep MUSE Guaranteed Time Observations. We estimate the total amount of diffuse ionised gas to be of the order of (~5+-3)x10^10 Msun and explore its physical properties to understand its origin and the source(s) of the ionisation. The MUSE data allow the identification of a dozen of group members embedded in this structure from emission and absorption lines. We extracted spectra from small apertures defined for both the diffuse ionised gas and the galaxies. We investigated the kinematics and ionisation properties of the various galaxies and extended gas regions thanks to line diagnostics (R23, O32 and [OIII]/Hβ) available within the MUSE wavelength range. We compared these diagnostics to photo-ionisation models and shock models. The structure is divided in two kinematically distinct sub-structures. The most extended sub-structure of ionised gas is likely rotating around a massive galaxy and displays filamentary patterns linking some galaxies. The second sub-structure links another massive galaxy hosting an Active Galactic Nucleus to a low mass galaxy but also extends orthogonally to the AGN host disk over ~35 kpc. This extent is likely ionised by the AGN itself. The location of small diffuse regions in the R23 vs. O32 diagram is compatible with photo-ionisation. However, the location of three of these regions in this diagram (low O32, high R23) can also be explained by shocks, which is supported by their large velocity dispersions. One edge-on galaxy shares the same properties and may be a source of shocks. Whatever the hypothesis, the extended gas seems to be non primordial. We favour a scenario where the gas has been extracted from galaxies by tidal forces and AGN triggered by interactions between at least the two sub-structures.
description: 21 pages, 12 figures, 3 tables, accepted for publication in A&A (27 October 2017)
Detailed description of DNA procedures and methodological considerations from High resistance towards herbivore-induced habitat change in a high Arctic arthropod community
Creators: name: Schmidt, Niels M.
name: Mosbacher, Jesper B.
name: Eitzinger, Bernhard
name: Vesterinen, Eero J.
name: Roslin, Tomas
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Molecular Biology
subject: Ecology
subject: FOS: Biological sciences
subject: 60114 Systems Biology

description: DNA procedures
On Protected Realizations of Quantum Information
Creators: name: Knill, E.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: There are two complementary approaches to realizing quantum information so that it is protected from a given set of error operators. Both involve encoding information by means of subsystems. One is initialization-based error protection, which involves a quantum operation that is applied before error events occur. The other is operator quantum error correction, which uses a recovery operation applied after the errors. Together, the two approaches make it clear how quantum information can be stored at all stages of a process involving alternating error and quantum operations. In particular, there is always a subsystem that faithfully represents the desired quantum information. We give a definition of faithful realization of quantum information and show that it always involves subsystems. This justifies the "subsystems principle" for realizing quantum information. In the presence of errors, one can make use of noiseless, (initialization) protectable, or error-correcting subsystems. We give an explicit algorithm for finding optimal noiseless subsystems. Finding optimal protectable or error-correcting subsystems is in general difficult. Verifying that a subsystem is error-correcting involves only linear algebra. We discuss the verification problem for protectable subsystems and reduce it to a simpler version of the problem of finding error-detecting codes.
description: 17 pages
The Potential Roles of Fecundity, Young of the Year Growth, and Young of the Year Mortality on the Displacement of Orconectes virilis by Orconectes rusticus in the Monocacy River, Maryland.
Creators: name: Selckman, Gordon M.
Publisher: name: Maryland Shared Open Access Repository
Year: 2016

description: The invasive rusty crayfish (Orconectes rusticus) is displacing virile crayfish (Orconectes virilis) in the Monocacy River, Maryland. During 2011 and 2012, I investigated young of the year (YOY) life history traits of both crayfishes to identify displacement mechanisms. I sampled sites dominated by 0. rusticus and 0. virilis and a population interface site. Orconectes virilis was more fecund than 0. rusticus. 0. virilis YOY experienced reduced survival, reduced growth, and smaller year-end size at the overlap site. Orconectes rusticus juveniles show increased growth at the overlap site when compared to 0. rusticus at the dominant site. The 0. virilis YOY population experienced a large loss in YOY by early summer at the overlap site. A decline of 0. virilis YOY was not observed at the 0. virilis dominant site. My results suggest 0. virilis displacement occurs during its YOY stage, and is related to the presence of 0. rusticus.