cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Numerical study on droplet motions on heterogeneous substrates: from a wettability viewpoint
Creators: name: YUXIANG WANG
Publisher: name: Monash University
Year: 2019
Subjects: subject: 30603 Colloid and Surface Chemistry
subject: FOS: Chemical sciences
subject: 91501 Computational Fluid Dynamics
subject: FOS: Other engineering and technologies
subject: 20406 Surfaces and Structural Properties of Condensed Matter
subject: FOS: Physical sciences

description: This thesis numerically studies four kinds of wettability-related droplet motions on solid surfaces, including droplet wetting on stripe-patterned surfaces, droplet flowing in non-wetting capillaries with wettability gradient, droplet sliding on homogeneous and stripe-patterned surfaces, and droplet impacting on groove-patterned surfaces. Numerical method many-body dissipative particle dynamics (MDPD) is used to perform all simulations in this project. For all the droplet motions, the wettability is the core aspect to govern the interaction between the droplet and solid surface while different interaction conditions like driving force, impact velocity, space et al. further affect the specific droplet dynamics on these surfaces.
MPEC 2023-H109 : DAILY ORBIT UPDATE (2023 April 20)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Microlensing towards the Magellanic Clouds and M31: is the quest for MACHOs still open?
Creators: name: Novati, S. Calchi
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Microlensing is the tool of choice for the search and the analysis of compact halo objects ("MACHOs"), a still viable class of dark matter candidates at the galactic scale. Different analyses point towards an agreement in excluding dark matter MACHOs of less than about 0.1 solar mass; it remains however an ongoing debate for values in the mass range (0.1-1) solar mass. The more robust constraints, though not all in agreement, come from the observational campaigns towards the Magellanic Clouds (the LMC and the SMC). The analyses towards the nearby galaxy of M31, in the so called "pixel lensing" regime, have expanded the perspectives in this field of research. In this contribution first we draw a critical view on recent results and then we focus on the pixel lensing analysis towards M31 of the PLAN collaboration.
description: 8 pages, no figures; to appear in the Proceedings of the 3rd Italian-Pakistani Workshop on Relativistic Astrophysics, Lecce 20-22 June 2011, published in Journal of Physics: Conference Series (JPCS)
GAS-SOLID FLOW CHARACTERISTICS AND SCALING OF SPOUTED BEDS WITH NON-SPHERICAL PARTICLES
Creators: name: XUEJIAO LIU
Publisher: name: Monash University
Year: 2020
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Spouted bed as one of the typical fluidization reactors, has been widely used in many industrial areas. However up to today, our knowledge on spouted bed is still very limited, especially in the aspects of the spouting dynamics of non-spherical particles and the scale-up of reactors, leading to numerous difficulties in the design, operation or optimization of spouted beds. This thesis has been devoted to revealing the complex spouting characteristics of non-spherical particles and the scaling relationships of spouted beds by experimental and numerical modelling approaches.
title: The Analysis and Impact of Artificial Intelligence on Job Loss
Creators: name: Baratz, Ava
Publisher: name: Old Dominion University Libraries
Year: 2023

description: This paper illustrates the analysis and impact of Artificial Intelligence (AI) on job loss across various industries. This paper will discuss an overview of AI technology, a brief history of AI in industry, the positive impacts of AI, the negative impacts of AI on employment, AI considerations that contribute to job loss, the future outlook of AI, and employment loss mitigation strategies Various professional source articles and reputable blog posts will be used to finalize research on this topic.
Study of Lead Halide Perovskite Single Crystals
Creators: name: WENXIN MAO
Publisher: name: Monash University
Year: 2019
Subjects: subject: 91205 Functional Materials
subject: FOS: Materials engineering
subject: 90608 Renewable Power and Energy Systems Engineering (excl. Solar Cells)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Organo-lead halide perovskites (OHPs) have recently emerged as a new class of exceptional optoelectronic materials, which has been used in many applications, including solar cells, light emitting diodes, and photodetectors. However, despite the thorough studies into lead halide perovskites during over past 10 years, there are still many unknowns concerning both the device performance and the stability, which are strongly related to their crystal quality as well as their optoelectronic properties. This thesis reports on the study of perovskite crystal growth and the mechanism of light induced phase segregation and ion migration in mixed halide perovskite materials.
Methods for transcript variant discovery and alternative expression analysis : application to the study of fluorouracil resistance in colorectal cancer
Creators: name: Griffith, Malachi
Publisher: name: University of British Columbia
Year: 2010

description: RNA transcripts are expressed from tens of thousands of loci across the human genome. Several studies have suggested that many genes are alternatively expressed to produced multiple mRNA isoforms and many of these remain undiscovered. Identifying specific isoforms associated with human diseases such as cancer has potential to lead to improved treatments. The scale and complexity of the transcriptome present significant barriers to (1) identifying isoforms and (2) applying knowledge to human disease research. Recent advances in genome-wide microarray and sequencing platforms have begun to provide the capacity and resolution to address these challenges. The goal of this thesis was to develop novel methods that allow genome-wide identification and quantification of mRNA isoforms. I first approached this problem by creating a microarray design platform for alternative expression analysis called 'ALEXA-array' (www.AlexaPlatform.org). To evaluate the ALEXA-array approach I used it to generate a microarray design that I then used to measure differential expression of mRNA isoforms in 5-fluorouracil (5-FU) sensitive and resistant colorectal cancer cell lines. This approach identified several isoforms potentially involved in 5-FU resistance. While the ALEXA-array approach was successful, I identified several limitations of the method. For example, the approach was insensitive to isoforms with small differences in sequence content and limited by both the transcriptome annotations and the number of microarray features available at design time. I developed a second method, ‘ALEXA-seq’, to take advantage of advances in massively parallel sequencing. Applying this method to the same cell lines I showed that the approach was able to overcome many limitations of the microarray approach. Several additional candidate 5-FU resistance isoforms were identified. Both the ALEXA-array and ALEXA-seq approaches identified expression of an aberrant isoform of the uridine monophosphate synthetase as a top candidate. Interestingly, this gene was suspected to function in the conversion of 5-FU to active anti-cancer metabolites. Additional characterization was performed to elucidate the expression pattern, transcript diversity and sequence variation of this gene in a panel of cell lines and tumours. The methods presented here should help to identify mRNA isoforms with potential utility as therapeutic targets or as prognostic or diagnostic markers.
Learning Probabilistic Graphical Models for Identification of Dark Matter Signatures in Noisy Data
Creators: name: Peters, Christina
name: Higuera, Aaron
name: Liang, Shixiao
name: Oranday, Alex
name: Roy, Venkat
name: Bajwa, Waheed
name: Tunnell, Christopher
name: Shatkay, Hagit
Publisher: name: Zenodo
Year: 2020

description: Dark Matter comprises 85% of the Universe, yet there is no experimental knowledge of its properties. Direct detection experiments generate Petabytes of extremely noisy spatiotemporal data, in which scientists search for the signatures of exceptionally rare particles at the noise level of the sensors. Currently used techniques do not readily allow for domain knowledge to be incorporated into the models that are being built and learned for supporting this search. As a way of embedding domain knowledge into the solution, we propose using the framework of probabilistic graphical models, which can readily incorporate physical constraints and prior knowledge. The learned Probabilistic Graphical Model can be used to infer interaction positions of experimentally measured events, and thus uncover the meaningful signals in noisy detector data.
Conservative upper limits on WIMP annihilation cross section from Fermi-LAT $γ$-rays
Creators: name: Donato, F.
name: Calore, F.
name: De Romeri, V.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The spectrum of an isotropic extragalactic $γ$-ray background (EGB) has been measured by the Fermi-LAT telescope at high latitudes. Two new models for the EGB are derived from the subtraction of unresolved point sources and extragalactic diffuse processes, which could explain from 30% to 70% of the Fermi-LAT EGB. Within the hypothesis that the two residual EGBs are entirely due to the annihilation of dark matter (DM) particles in the Galactic halo, we obtain $conservative$ upper limits on their annihilation cross section \sigmav. Severe bounds on a possible Sommerfeld enhancement of the annihilation cross section are set as well. Finally, would {\sigmav} be inversely proportional to the WIMP velocity, very severe limits are derived for the velocity-independent part of the annihilation cross section.
description: Proceedings of XII Taup Conference, Munich, September 2011
Nanocellulose Gels: Concepts and Applications
Creators: name: LLYZA ELLENA MENDOZA
Publisher: name: Monash University
Year: 2019
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering
subject: 91210 Timber, Pulp and Paper
subject: FOS: Materials engineering

description: Cellulose can be processed into biodegradable and biocompatible hydrogels via a chemical reaction. These gels were produced and characterised to understand how they form in order to engineer them for applications. Low-density foams were produced from these hydrogels and demonstrated superabsorbent properties. Moreover, the gels were also utilised in biomedical applications as a medium for the separation of molecular mixtures. This work demonstrates the potential of cellulose-based gels to be a commercialised sustainable and renewable nanomaterial.
Bayesian joint modeling of multiple gene networks and diverse genomic data to identify target genes of a transcription factor
Creators: name: Wei, Peng
name: Pan, Wei
Publisher: name: arXiv
Year: 2012
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: We consider integrative modeling of multiple gene networks and diverse genomic data, including protein-DNA binding, gene expression and DNA sequence data, to accurately identify the regulatory target genes of a transcription factor (TF). Rather than treating all the genes equally and independently a priori in existing joint modeling approaches, we incorporate the biological prior knowledge that neighboring genes on a gene network tend to be (or not to be) regulated together by a TF. A key contribution of our work is that, to maximize the use of all existing biological knowledge, we allow incorporation of multiple gene networks into joint modeling of genomic data by introducing a mixture model based on the use of multiple Markov random fields (MRFs). Another important contribution of our work is to allow different genomic data to be correlated and to examine the validity and effect of the independence assumption as adopted in existing methods. Due to a fully Bayesian approach, inference about model parameters can be carried out based on MCMC samples. Application to an E. coli data set, together with simulation studies, demonstrates the utility and statistical efficiency gains with the proposed joint model.
description: Published in at http://dx.doi.org/10.1214/11-AOAS502 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Experimental And Numerical Study On Characteristics Of Coal Pressurized Grade Conversion In A Dual Fluidized Bed
Creators: name: GUANWEN ZHOU
Publisher: name: Monash University
Year: 2019
Subjects: subject: 91305 Energy Generation, Conversion and Storage Engineering
subject: FOS: Mechanical engineering

description: The pressurized grade conversion of coal based on the coal pyrolysis and semi-coke combustion was proposed in this study. A bench-scale experimental system of coal pressurized grade conversion was set up to investigate the influence of pyrolysis temperature, pressure , atmosphere and particle size on the pollutant emissions, pyrolysis production yield and ash properties. Based on the fundamental research, a pilot-scale dual fluidized bed platform with a capacity of 50kg/h was built and used to study the fluidization, transportation, pyrolysis and combustion of coal and semi-coke under different conditions. Finally, an industrial scale numerical model of a coal pressurized grade conversion reactor was developed.
Conceptual planning, EURAD Domain Insight
Creators: name: Mele
name: , Zeleznik
Publisher: name: Zenodo
Year: 2023
Subjects: Siting
Site selection process
Site screening
Conceptual planning
Geological disposal

description: The roadmap describes typical programme goals, activities and capabilities needed against 7 themes, which are each further broken down into sub-themes and domains in what we can call the Goals Breakdown Structure (GBS). This document provides the overall goal for the Conceptual planning domain (Identify key decision points, and develop screening guidelines to enable a facility to be located to match national performance criteria and socio-economic, political and environmental considerations), extracted from the EURAD Roadmap goals breakdown structure (GBS). This is supplemented by typical activities, according to phases of implementation, needed to achieve the domain goal. Activities are generic and are common to most regional and geological disposal programmes.
description: Reviewers: Jitka Mikšová (SURO), Wilfried Pfingsten (PSI)
A structured alternative to Prolog with simple compositional semantics
Creators: name: Porto, António
Publisher: name: arXiv
Year: 2011
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences
subject: D.3.1; D.3.3; F.3.2

description: Prolog's very useful expressive power is not captured by traditional logic programming semantics, due mainly to the cut and goal and clause order. Several alternative semantics have been put forward, exposing operational details of the computation state. We propose instead to redesign Prolog around structured alternatives to the cut and clauses, keeping the expressive power and computation model but with a compositional denotational semantics over much simpler states-just variable bindings. This considerably eases reasoning about programs, by programmers and tools such as a partial evaluator, with safe unfolding of calls through predicate definitions. An if-then-else across clauses replaces most uses of the cut, but the cut's full power is achieved by an until construct. Disjunction, conjunction and until, along with unification, are the primitive goal types with a compositional semantics yielding sequences of variable-binding solutions. This extends to programs via the usual technique of a least fixpoint construction. A simple interpreter for Prolog in the alternative language, and a definition of until in Prolog, establish the identical expressive power of the two languages. Many useful control constructs are derivable from the primitives, and the semantic framework illuminates the discussion of alternative ones. The formalisation rests on a term language with variable abstraction as in the λ-calculus. A clause is an abstraction on the call arguments, a continuation, and the local variables. It can be inclusive or exclusive, expressing a local case bound to a continuation by either a disjunction or an if-then-else. Clauses are open definitions, composed (and closed) with simple functional application (β-reduction). This paves the way for a simple account of flexible module composition mechanisms. Cube, a concrete language with the exposed principles, has been implemented.
description: 27th Int'l. Conference on Logic Programming (ICLP'11) Special Issue, 2011
Semitransparent and back-contact perovskite solar cells for the application in tandem solar cells
Creators: name: QICHENG HOU
Publisher: name: Monash University
Year: 2019
Subjects: subject: 90605 Photodetectors, Optical Sensors and Solar Cells
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 100706 Nanofabrication, Growth and Self Assembly
subject: FOS: Nanotechnology
subject: 91205 Functional Materials
subject: FOS: Materials engineering

description: Solar cells for electricity generation have been widely applied. However, most solar cells can only harvest a proportion of energy from the sunlight due to the light absorbing materials in the solar cells. Stacking solar cells that absorb different proportions of sunlight to make a tandem cell can harvest more energy from sunlight. In this thesis, solar cells using perovskites as the light absorbing materials have been developed for the application in tandem cells, e.g. perovskite/silicon tandem cells. Specifically, semitransparent perovskite solar cells employing transparent electrodes and back-contact perovskite solar cells have been developed as the solutions to problems involved in tandem cell application.
Biosphere model, EURAD Domain Insight
Creators: name: THORNE Michael
Publisher: name: Zenodo
Year: 2022
Subjects: Ecosystem
Community
Population
Landform
Catchment
Hydrology
Hydrogeology
Hydrochemistry

description: This domain is an integral part of the wider sub-theme directed to site description. It relates to the characterization or confirmation of surface ecosystem properties at the present day, but also to the obtaining and applying of data relevant to making projections of the potential evolution of surface ecosystem properties in the future. Thus, although the focus is on characterization, the information and approaches adopted are closely related to assessing how future climate change and landscape development would affect surface ecosystem properties.
description: Reviewer: Elena ABARCA (Amphos 21)
Twisted acceleration-enlarged Newton-Hooke space-times and breaking classical symmetry phenomena
Creators: name: Daszkiewicz, Marcin
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We find the subgroup of classical acceleration-enlarged Newton-Hooke Hopf algebra which acts covariantly on the twisted acceleration-enlarged Newton-Hooke space-times. The case of classical acceleration-enlarged Galilei quantum group is considered as well.
description: 11 pages, no figures
title: A Review of Threat Vectors to DNA Sequencing Pipelines
Creators: name: Rector, Tyler
Publisher: name: Old Dominion University Libraries
Year: 2023

description: Bioinformatics is a steadily growing field that focuses on the intersection of biology with computer science. Tools and techniques developed within this field are quickly becoming fixtures in genomics, forensics, epidemiology, and bioengineering. The development and analysis of DNA sequencing and synthesis have enabled this significant rise in demand for bioinformatic tools. Notwithstanding, these bioinformatic tools have developed in a research context free of significant cybersecurity threats. With the significant growth of the field and the commercialization of genetic information, this is no longer the case. This paper examines the bioinformatic landscape through reviewing the biological and cybersecurity threats within the bioinformatics pipeline. It is found that there are significant security deficits within existing bioinformatic databases. Additionally, it is found that there is a theoretical trojan threat posed by unverified malicious DNA sequences.
Double-Well Optical Lattices with Atomic Vibrations and Mesoscopic Disorder
Creators: name: Yukalov, V. I.
name: Yukalova, E. P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Double-well optical lattice in an insulating state is considered. The influence of atomic vibrations and mesoscopic disorder on the properties of the lattice are studied. Vibrations lead to the renormalization of atomic interactions. The occurrence of mesoscopic disorder results in the appearance of first-order phase transitions between the states with different levels of atomic imbalance. The existence of a nonuniform external potential, such as trapping potential, essentially changes the lattice properties, suppressing the disorder fraction and rising the transition temperature.
description: Latex file, 21 pages, 2 figures
Bacterial Methane Monooxygenase: from Molecular Evolution to Biotechnology
Creators: name: CRAIG DAVID OSBORNE
Publisher: name: Monash University
Year: 2020
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Biochemistry
subject: Biotechnology
subject: 60309 Phylogeny and Comparative Analysis

description: Methane is both a valuable source of energy and a potent greenhouse gas; its oxidation to methanol produces a useful and storable liquid fuel. In nature and in biotechnology, methane oxidation is undertaken by microorganisms called methanotrophs, which are slow growing. This research aimed to improve the biological conversion of methane and achieved this by retracing the evolution of the enzyme systems that enabled methane metabolism in these microbes. Then, this knowledge was successfully applied to the production of enzymes in a fast growing, industrially-relevant microbial host.
Multi-wavelength observations of the young binary system Haro 6-10: The case of misaligned discs
Creators: name: Roccatagliata, V.
name: Ratzka, Th.
name: Henning, Th.
name: Wolf, S.
name: Leinert, Ch.
name: Bouwman, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context. We present a multi-wavelength, high-resolution observational survey of the young binary system Haro 6-10 (GV Tau, IRAS 04263+2426), which is harbouring one of the few known infrared companions. Aims. The primary goal of this project is to determine the physical and geometrical properties of the circumstellar and circumbinary material in the Haro 6-10 system. Methods. High-resolution optical (HST/WFPC2) and near-infrared (VLT/NACO) images in different bands were analysed to investigate the large-scale structures of the material around the binary.Mid-infrared interferometry (VLTI/MIDI) and spectroscopy (TIMMI2 at the 3.6m ESO telescope) were carried out to determine the structure and optical depth of the circumstellar material around the individual components. Results. The multi-wavelength observations suggest that both components of the binary system Haro 6-10 are embedded in a common envelope. The measured extinction indicates a dust composition of the envelope similar to that of the interstellar medium. Each component of the system has a circumstellar disc-like structure typical of young stars. The discs are highly misaligned: the northern component is seen almost edge-on and the southern component is an almost face-on disc. Conclusions. The two main formation scenarios of binary systems with misaligned discs are the gravitational capture of a passing object in a dense environment, and the fragmentation of the collapsing molecular cloud. Given the low-density environment of the Taurus-Aurigae star-forming region, the first scenario is unlikely for Haro 6-10. The binary system most probably formed via fragmentation of two different parts of the collapsing molecular cloud combined with other dynamical processes related to the cloud and/or the protostars. This can be the explanation also for other binary systems with an infrared companion.
description: accepted for publication in A&A on July 15, 2011
R-Symmetry and Gravitino Abundance
Creators: name: Dalianis, Ioannis
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Supersymmetry breaking sectors generically have an approximate global U(1) $R$-symmetry. Thermal effects tend to restore the $R$-symmetry in the reheated early universe. We revisit the gravitino generation from the thermal plasma and we argue that an $R$-symmetric phase suppresses the gaugino masses and thereby the production of the helicity $\pm 1/2$ gravitino component. For reasonable values of the hidden sector parameters the gravitino can account for the dark matter of the universe with a relic abundance characterized by a remarkable insensitivity to the reheating temperature.
description: references, comments added; minor changes
A Pilot Study of Temporomandibular Disorder (TMD) Pain and Nocturnal Autonomic Nervous System (ANS) Associated Masticatory Muscle Activity
Creators: name: Zegarowski, Brandon
Publisher: name: Oregon Health and Science University
Year: 2023
Subjects: subject: Temporomandibular Joint Disorders
subject: Temporomandibular Joint Disorders, Pain

description: This pilot study tested for differences in autonomic nervous system and masticatory muscle activities in subjects with and without TMD-associated pain (±Pain).
Scenario development and FEP analysis, EURAD Domain Insight
Creators: name: Lommerzheim
Publisher: name: Zenodo
Year: 2022
Subjects: Features
Events and Processes
FEP
Scenario development
Long-term Safety Assessment

description: The roadmap describes typical programme goals, activities and capabilities needed against 7 themes, which are each further broken down into sub-themes and domains in what we can call the Goals Breakdown Structure (GBS). This document provides the overall goal for the Scenario development and FEP analysis domain (Evaluate post-closure features, events and processes relevant to safety to create plausible scenarios of disposal system behaviour ), extracted from the EURAD Roadmap goals breakdown structure (GBS). This is supplemented by typical activities, according to phases of implementation, needed to achieve the domain goal. Activities are generic and are common to most regional and geological disposal programmes.
description: Reviewers: Nadja ŽELEZNIK (EIMV), Jacques WENDLING (ANDRA)
Synthesis of Vanadium Dioxide Particles for Smart Window, Sensing and Other Applications
Creators: name: YUAN FENG
Publisher: name: Monash University
Year: 2019
Subjects: subject: 91205 Functional Materials
subject: FOS: Materials engineering
subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering
subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: Vanadium dioxide has its promising thermochromic property, both transmittance and resistance would change significantly responding to temperature variation near its phase transition temperature. Two major issues, including high production cost and few applications, hinder the wide use of vanadium dioxide products. This thesis shows some feasible ways to reduce the vanadium dioxide smart window cost for achieving the requirement of large-scale production in industry and demonstrates some potential applications rather than the smart window.
Developing bioinformatics tools and analyses on protein indels and protein-protein interactions : novel applications for drug discovery in Staphylococcus aureus
Creators: name: Hsing, Michael
Publisher: name: University of British Columbia
Year: 2010

description: Infectious diseases caused by bacterial pathogens continue to be major public health concerns affecting millions of human lives annually, as conventional treatment via antibiotics has lost its effectiveness due to growing problems of drug resistance. Recent advancements in systems biology, high-throughout sequencing, protein interaction study and computer-aided drug development can offer possible solutions to antibiotic resistance through discovery of novel antimicrobials. The thesis describes several bioinformatics approaches that focus on protein interaction network (PIN) studies, analyses of targetable protein indels (insertions and deletions) and virtual compound screening for new antibacterial candidates – approaches integrated into an antibiotic discovery pipeline for methicillin-resistant Staphylococcus aureus (MRSA252). In the course of the described work we identified new drug targets corresponding to highly interacting proteins (hubs) through comprehensive PIN analysis in MRSA252. The advantage of using hub proteins as targets is established by their essentiality, non-replaceable PIN position and lower rate of mutation, all of which can help to counter bacterial resistance. To accelerate these studies hub predicting tools have been developed to assist proteomics experiments for PIN discovery and to facilitate drug target identification in pathogens. Because some bacterial proteins are conserved in humans, we applied the indel (insertion or deletion) concept to locate unique compound-binding sites that enabled us to specifically target conserved and essential bacterial hubs. We demonstrated associations between the presence of sizable indels in proteins with their essentiality and network rewiring capability, which established indels as potential markers for drug targets. To provide the research community a fast and user-friendly web portal for identification and characterization of indel-bearing drug targets, the Indel PDB database has been developed to characterize the functional and structural features of 117,266 indel sites across numerous species. Finally, combining the above bioinformatics methodologies with a rapid and efficient procedure of virtual screening allowed discovery of compounds that effectively inhibited MRSA252 cell growth with no signs of human toxicity. We anticipate that the drug discovery pipeline along with established MRSA PIN resource, hub prediction tools and indel database will provide a framework for the development of next-generation antibiotics in other existing or emerging pathogens.
Tensorial mobilities for accurate solution of transport problems in models with diffuse interfaces
Creators: name: Nicoli, Matteo
name: Plapp, Mathis
name: Henry, Hervé
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The general problem of two-phase transport in phase-field models is analyzed: the flux of a conserved quantity is driven by the gradient of a potential through a medium that consists of domains of two distinct phases which are separated by diffuse interfaces. It is shown that the finite thickness of the interfaces induces two effects that are not present in the analogous sharp-interface problem: a surface excess current and a potential jump at the interfaces. It is shown that both effects can be eliminated simultaneously only if the coefficient of proportionality between flux and potential gradient (mobility) is allowed to become a tensor in the interfaces. This opens the possibility for precise and efficient simulations of transport problems with finite interface thickness.
description: 14 pages, 4 figures
A Dry Spinning Approach to Smart Fiber-Based Stretchable Electronics
Creators: name: YUNMENG ZHAO
Publisher: name: Monash University
Year: 2019
Subjects: subject: 30107 Sensor Technology (Chemical aspects)
subject: FOS: Chemical sciences
subject: 100703 Nanobiotechnology
subject: FOS: Nanotechnology
subject: 100705 Nanoelectronics
subject: 91305 Energy Generation, Conversion and Storage Engineering
subject: FOS: Mechanical engineering

description: This thesis develops a novel dry spinning approach to the smart fiber-based stretchable electronics. It covers the materials, fabrication methods, structure designs, characterizations, and demonstrations of three wearable devices based on the dry-spun stretchable fiber conductors, indicating that the dry spinning approach provides a new path to the wearable textile electronics.
Investigation of New Redox Active Materials for Thin Film Solar Cells
Creators: name: REBECCA ANN MILHUISEN
Publisher: name: Monash University
Year: 2019
Subjects: subject: 90605 Photodetectors, Optical Sensors and Solar Cells
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This thesis explores novel charge-transporting materials that are critically important for the advancement of emerging solar technologies. The work demonstrated in this thesis opens up new possibilities for the design of efficient and versatile charge-transporting materials that are inexpensive, earth-abundant and easy to process in the lead-up towards the manufacturing of cheap solar cells.
THE DISTRIBUTED KNOWLEDGE DISTILLATION FRAMEWORK FOR FINANCIAL FRAUD PREVENTION BASED ON TRANSFORMER
Creators: name: ADVANCED RESEARCH AND INNOVATIONS JOURNAL
Publisher: name: Zenodo
Year: 2025

description: Financial fraud cases causing serious damage to the interests of investors are not uncommon. As a result, a wide range of intelligent detection techniques are put forth to support financial institutions’ decision-making. Currently, existing methods have problems such as poor detection accuracy, slow inference speed, and weak generalization ability. Therefore, we suggest a distributed knowledge distillation architecture for financial fraud detection based on Transformer. Firstly, the multi-attention mechanism is used to give weights to the features, followed by feed-forward neural networks to extract high-level features that include relevant information, and finally neural networks are used to categorize financial fraud. Secondly, for the problem of inconsistent financial data indicators and unbalanced data distribution focused on different industries, a distributed knowledge distillation algorithm is proposed. This algorithm combines the detection knowledge of the multi-teacher network and migrates the knowledge to the student network, which detects the financial data of different industries. The final experimental results show that the proposed method outperforms other methods in terms of F1 score (92.87%), accuracy (98.98%), precision (81.48%), recall (95.45%), and AUC score (96.73%) when compared to the traditional detection methods.
Biorefinery Opportunities in a Thermomechanical Pulping Mill
Creators: name: WICKRAMARACHCHIGE DON THILINA LAKMAL GUNAWARDHANA
Publisher: name: Monash University
Year: 2019
Subjects: subject: 100302 Bioprocessing, Bioproduction and Bioproducts
subject: FOS: Industrial biotechnology
subject: 91210 Timber, Pulp and Paper
subject: FOS: Materials engineering

description: An Australian paper mill, which produces newsprint, was analyzed for waste streams for possible value-addition. Four process streams, a waste fiber stream, a process water stream and two wastewater streams, were identified as the potential targets for value-addition. Three potential value-added products from the above four streams were identified. The waste fiber stream could be successfully upgraded and added back to the papermaking process saving 10 tonnes per day of fiber. Two valuable groups of chemicals with potential pharmaceutical applications, resin acids, and terpenes, were successfully recovered from wastewater streams.
Ordered Mesoporous Carbons as a Versatile Gas Adsorbent
Creators: name: YITIAN MENG
Publisher: name: Monash University
Year: 2019
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Ordered mesoporous carbons (OMCs) are carbon materials which have abundant nanopores ranging from 2 nm to 50 nm, with most of the pores ordered and uniform-sized. The OMCs have large surface area and pore volume comparable to conventional activated carbon materials, making it a promising gas adsorbent. This thesis investigated the application of OMCs as a versatile gas adsorbent and compared its adsorption performance with a commercially available activated carbon. The understandings achieved in this thesis contributed to the knowledge in (1) the application of the OMCs as a gas adsorbent alternative to conventional activated carbons (2) methods of modifying the OMC material to adsorb different types of gas pollutants.
Surface plasmon resonance under conditions of electromagnetically induced transparency
Creators: name: Du, Chunguang
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optics (physics.optics)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A scheme for a surface plasmon resonance system under conditions of electromagnetically induced transparency (EIT) is proposed. The system is composed of three layers: a prism, a thin metal film, and a hybrid dielectric consisting of EIT atoms and a background substance. A probe and a coupling laser beam are input. Corresponding analytical formulas are derived for the cases when one or both of the laser beams excite surface plasmon polaritons at the metal/dielectric interface. Under resonance conditions, an extremely sharp dip appears in the reflectivity-frequency spectrum of the probe field, revealing new properties of two-dimensional EIT. The reflectivity is extremely sensitive to shifts in the laser frequencies and atomic levels, and to variations of permittivity of the substrate. This EIT-SPR system may to be used for novel magnetometers and biosensors.
Dipole-Field-Tuning of Back-Contact Perovskite Solar Cells
Creators: name: XIONGFENG LIN
Publisher: name: Monash University
Year: 2019
Subjects: subject: 90605 Photodetectors, Optical Sensors and Solar Cells
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 100706 Nanofabrication, Growth and Self Assembly
subject: FOS: Nanotechnology

description: Hybrid organic-inorganic halide perovskite solar cells (PSCs) have demonstrated huge potential in becoming a promising alternative to commercially available photovoltaic technologies. For a PSC to be efficient, it typically needs to be “sandwiched” between thin charge transporting layers, which effectively extract photogenerated charges. This configuration affords high-efficiency solar cells, but results in significant performance and fabrication challenges, which limit the further improvement of this photovoltaic material towards the Shockley–Queisser limit. This thesis presents a novel device concept, along with an investigation into the device physics, with the aim of exploring the possibility of pushing PSCs towards their theoretical limit.
In-situ Crystallization via Counter-Current Spray-Dryer: Mechanism of Particle Crystallization through spray drying
Creators: name: SOROUSH SHAKIBA ESFAHANI
Publisher: name: Monash University
Year: 2019
Subjects: Uncategorized

description: Stability, size and shape are among the main factors influence the effectiveness of drugs in powder form. Crystalline particles have high stability however, manufacturing of crystalline particle in certain size and shape is challenging. This thesis investigated the potential of counter current spray dryer for manufacturing crystalline particle and developed a theoretical model for prediction of surface structure of crystalline particles.
Einmal Heterotopie und zurück. Thomas Hirschhorns Bataille-Monument auf der Documenta 11
Creators: name: Saéz, Susana
Publisher: name: Humboldt-Universität zu Berlin
Year: 2002
Subjects: subject: Kunst
subject: Dokumenta
subject: Hirschhorn
subject: Aktion
subject: 700 Künste

description: Ein Kunstwerk der anderen Art. Anfahrt inklusive. In Thomas Hirschhorns Bataille-Monument schlägt das Herz der Documenta 11. So lautet jedenfalls das Urteil der meisten Besucher und kritischen Beäuger der diesjährigen Kasseler Kunstmeile. Für hundert Tage hat der Schweizer Trash-Künstler, weitab vom traditionellen Trubel rund um das Fridericianum, eine acht Stationen umfassende citta ideale errichtet, die dem französischen Allroundgenie Georges Bataille gewidmet ist. Im Vordergrund steht dabei Batailles Idee der produktiven Verausgabung, die als Theorie des "vermeintlich Unzweckmäßigen" zu verstehen ist. Im Zeitalter grenzenloser Profithascherei ist die Verklärung des scheinbar Ineffizienten zweifellos als Affront zu verstehen. Batailles philosophisches Werk hat auf diese Weise Einlass in einer Gegend gefunden, in der Arbeitslosigkeit, Gewalt und Resigniertheit an der Tagesordnung stehen. Ohne Hirschhorns Engagement wäre das Kunst-Spektakel wohl unbemerkt an der Wöhler-Siedlung vorbeigerauscht. Doch der Schweizer Künstler hat gemeinsam mit den hier Ansässigen seine sozialutopische Installation umgesetzt und fordert so den Documenta-Besucher auf, sich in den Kasseler Norden zu begeben und sich auf ein Mikrokosmos einzulassen, der sich als Heterotopie in eine Welt eingenistet hat, die meilenweit von jeglichen Ambitionen der Kunst zu sein scheint. "Es gibt ... in jeder Zivilisation ... wirkliche Orte ... tatsächlich realisierte Utopien, in denen die wirklichen Plätze innerhalb der Kultur gleichzeitig repräsentiert, bestritten und gewendet sind. Weil diese Orte ganz anders sind als alle Plätze, die sie reflektieren oder von denen sie sprechen, nenne ich sie ... Heterotopien.", Michel Foucault
A CFD-DEM simulation of food grain drying process in a fluidised bed
Creators: name: JANNATUL AZMIR
Publisher: name: Monash University
Year: 2019
Subjects: subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Drying is the most important step for post-harvest processing of food grains. This project developed a food grain drying model by combining computational fluid dynamics and discrete element method in a fluidised bed. The model incorporated heat transfer sub-models, a water evaporation sub-model in resemblance to a chemical reaction and a shrinkage sub-model. The model is first tested against experimental data from literature in terms of drying and volume shrinkage curves. Then the effects of operating parameters, grain properties and bed geometries on drying and shrinkage rates and dried product quality are quantified and discussed with the grain scale information.
Building micro-soccer-balls with evaporating colloidal fakir drops
Creators: name: Marin, Alvaro G.
name: Susarrey-Arce, Arturo
name: Gelderblom, Hanneke
name: van Houselt, Arie
name: Lefferts, Leon
name: Gardeniers, Han
name: Lohse, Detlef
name: Snoeijer, Jacco
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Evaporation-driven particle self-assembly can be used to generate three-dimensional microstructures. We present a new method to create these colloidal microstructures, in which we can control the amount of particles and their packing fraction. To this end, we evaporate colloidal dispersion droplets on a special type of superhydrophobic micro-structured surface, on which the droplet re- mains in Cassie-Baxter state during the entire evaporative process. The remainders of the droplet consist of a massive spherical cluster of the microspheres, with diameters ranging from a few tens up to several hundreds of microns. We present scaling arguments to show how the final particle packing fraction of these balls depends on the dynamics of the droplet evaporation.
description: Manuscript Submitted to Physical Review Letters, 29th February 2012
Non-congruence of liquid-gas phase transition of asymmetric nuclear matter
Creators: name: Maruyama, Toshiki
name: Tatsumi, Toshitaka
Publisher: name: arXiv
Year: 2012
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We first explore the liquid-gas mixed phase in a bulk calculation, where two phases coexist without the geometrical structures. In the case of symmetric nuclear matter, the system behaves congruently, and the Maxwell construction becomes relevant. For asymmetric nuclear matter, on the other hand, the phase equilibrium is no more attained by the Maxwell construction since the liquid and gas phases are non-congruent; the particle fractions become completely different with each other. One of the origins of such non-congruence is attributed to the large symmetry energy. Subsequently we explore the charge-neutral nuclear matter with electrons by fully applying the Gibbs conditions to figure out the geometrical (pasta) structures in the liquid-gas mixed phase. We emphasize the effects of the surface tension and the Coulomb interaction on the pasta structures. We also discuss the thermal effects on the pasta structures.
description: proceedings of PANIC 2011
Two-dimensional Plasmonic Nanoparticle Superlattices: Synthesis, Fabrication & Application
Creators: name: DASHEN DONG
Publisher: name: Monash University
Year: 2019
Subjects: subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: Two-dimensional free-standing plasmonic superlattice (Plasmene) shows the superior ability to engineer properties by altering the particle size, shape, composition and interspacing. Despite the current success, there are still unsolved problems. This thesis aims to address issues from synthesis of plasmonic particles to fabrication of Plasmene using new building blocks and investigation on properties related applications. The successes in the synthesis of complex bimetallic nanoparticles and the fabrication of new plasmene nanosheets allow a better understanding of plasmonic coupling interactions of nanoparticles and self-assembly process. The demonstrated utilization of plasmene in immunoassay and optics further integrate the downstream real-world forensic applications.
Connecting the Reentrant Insulating Phase and the Zero Field Metal-Insulator Transition in a 2D Hole System
Creators: name: Qiu, Richard L. J.
name: Gao, Xuan P. A.
name: Pfeiffer, L. N.
name: West, K. W.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present the transport and capacitance measurements of 10nm wide GaAs quantum wells with hole densities around the critical point of the 2D metal-insulator transition (critical density $p_c$ down to 0.8$\times10^{10}$/cm$^2$, $r_s\sim$36). For metallic hole density $p_c < p
description: pdf with higher resolution figures and other related papers can be found at http://gaogroup.case.edu