cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Young people who use drugs and the child welfare system : evidence to improve outcomes
Creators: name: Barker, Brittany
Publisher: name: University of British Columbia
Year: 2019

description: Background: Youth exposed to the child welfare system (CWS) experience elevated rates of subsequent homelessness and other negative health-related outcomes. The objectives of this dissertation were to: systematically search and synthesize the literature on the relationship between the CWS and substance use outcomes; examine possible intergenerational impacts of the residential school system (RSS) on CWS-involvement among Indigenous youth; investigate the relationship between the CWS and injection initiation among street-involved youth; and evaluate if utilizing services while aging-out of care is associated with improved long-term health-related outcomes among a high-risk sample of younger people who use drugs (PWUD). Methods: Data were derived from two harmonized, community-recruited prospective cohorts of PWUD in Vancouver, Canada. Study participants were seen semi-annually to complete an interviewer-administered questionnaire. Multivariable logistic regression analyses were used to investigate the intersections between social and structural forces associated with CWS-involvement and their influence on substance use and health-related outcomes. Results: Collectively, the findings of this dissertation indicate that the CWS and related exposures act as a risk environment for youth in care. Having a history of CWS-involvement was independently associated with initiating injection drug use before age 18 among street-involved youth. Among Indigenous PWUD, immediate familial RSS exposure (i.e., grandparent, parent) was common (66.3%) and independently associated with a higher likelihood for having been personally placed into the CWS. Further, when controlling for familial RSS exposure, a non-detectable difference in the odds of CWS-involvement between Indigenous and non-Indigenous PWUD was found. Among PWUD, approximately half of the sample utilized financial, independent living, and medical services while aging-out, but low utilization rates and high unmet demand were reported for education, employment, and life-skills services. PWUD who utilized a higher number of transitional services while aging-out were significantly less likely to report subsequent daily drug use or housing instability. Conclusions: This dissertation identifies several policy opportunities to improve the health and wellbeing of marginalized youth in care, and particularly supports calls to extend care and services to facilitate successful transitions to independence among those who age-out. Evidence-based interventions that address the upstream social and structural determinants of CWS-involvement are also urgently needed.
Ten myths about open science
Creators: name: Stupavská, Libuše
Publisher: name: Zenodo
Year: 2021
Subjects: open science
open access
research data management
RDM
open data

description: A flyer summarizing ten common myths about open science.
description: Podpořeno projektem OP VVV Rozvoj kapacit pro výzkum a vývoj UK II, reg. č.: CZ.02.2.69/0.0/0.0/18_054/0015222.
The Heterogeneous Surface of Asteroid (16) Psyche
Creators: name: Cambioni, Saverio
name: de Kleer, Katherine
name: Shepard, Michael
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Main-belt asteroid (16) Psyche is the largest M-type asteroid, a class of object classically thought to be the metal cores of differentiated planetesimals and the parent bodies of the iron meteorites. de Kleer, Cambioni, and Shepard (2021, https://doi.org/10.3847/psj/ac01ec) presented new data from the Atacama Large Millimeter Array (ALMA), from which they derived a global best-fit thermal inertia and dielectric constant for Psyche, proxies for regolith particle size, porosity, and/or metal content, and observed thermal anomalies that could not be explained by surface albedo variations only. Motivated by this, here we fit a model to the same ALMA data set that allows dielectric constant and thermal inertia to vary across the surface. We find that Psyche has a heterogeneous surface in both dielectric constant and thermal inertia but, intriguingly, we do not observe a direct correlation between these two properties over the surface. We explain the heterogeneity in dielectric constant as being due to variations in the relative abundance of metal and silicates. Furthermore, we observe that the lowlands of a large depression in Psyche's shape have distinctly lower thermal inertia than the surrounding highlands. We propose that the latter could be explained by a thin mantle of fine regolith, fractured bedrock, and/or implanted silicate-rich materials covering an otherwise metal-rich surface. All these scenarios are indicative of a collisionally evolved world.
description: Paper is published open-access here: https://agupubs.onlinelibrary.wiley.com/doi/full/10.1029/2021JE007091
title: Ð¢ÑÑÐ±Ð¾Ð²ÐµÐ½ÑÐ¸Ð»ÑÑÐ¾ÑÐ½ÑÐ¹ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»Ñ SaM146 Ñ ÑÑÐ³Ð¾Ð¹ 80 ÐºÐ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Turbofan engine SaM146 with 80 kN thrust
Creators: name: ÐÐ½Ð°Ð½ÑÐ¸Ð½, ÐÐ¸ÐºÐ¸ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2022
Subjects: Ð³Ð°Ð·Ð¾ÑÑÑÐ±Ð¸Ð½Ð½ÑÐ¹ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»Ñ
Ð°Ð²Ð¸Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¹ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»Ñ
ÐºÐ¾Ð¼Ð¿ÑÐµÑÑÐ¾Ñ
ÐºÐ°Ð¼ÐµÑÐ° ÑÐ³Ð¾ÑÐ°Ð½Ð¸Ñ
ÑÑÑÐ±Ð¸Ð½Ð°
Ð»Ð¾Ð¿Ð°ÑÐºÐ°
Ð´Ð¸ÑÐº
ÑÐ¾ÑÐ¾Ñ
gas-turbine engine
transferring device
compressor
combustion chamber
turbine
blade
disc
rotor

description: Ð¢ÐµÐ¼Ð° Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ: Â«Ð¢ÑÑÐ±Ð¾Ð²ÐµÐ½ÑÐ¸Ð»ÑÑÐ¾ÑÐ½ÑÐ¹ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»Ñ SaM146 Ñ ÑÑÐ³Ð¾Ð¹ 80 ÐºÐÂ».Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ Ð°Ð²Ð¸Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð³Ð°Ð·Ð¾ÑÑÑÐ±Ð¸Ð½Ð½Ð¾Ð³Ð¾ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»Ñ Ð¿Ð¾ Ð¿ÑÐ¾ÑÐ¾ÑÐ¸Ð¿Ñ SaM146.Ð ÑÐ°Ð±Ð¾ÑÐµ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐ°ÑÑÐµÑ ÑÐµÐ¿Ð»Ð¾Ð²Ð¾Ð¹ ÑÑÐµÐ¼Ñ, Ð¿ÑÐ¸Ð±Ð»Ð¸Ð¶ÐµÐ½Ð½ÑÐ¹ ÑÐ°ÑÑÐµÑ ÐºÐ¾Ð¼Ð¿ÑÐµÑÑÐ¾ÑÐ°, ÑÐ°ÑÑÐµÑ ÑÑÑÐ±Ð¸Ð½Ñ, ÑÐ°ÑÑÐµÑ ÐºÐ°Ð¼ÐµÑÑ ÑÐ³Ð¾ÑÐ°Ð½Ð¸Ñ, Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ½Ð¾Ð¹ ÑÐ°ÑÑÐµÑ Ð»Ð¾Ð¿Ð°ÑÐºÐ¸, Ð´Ð¸ÑÐºÐ° Ð¸ ÑÐ¾ÑÐ¾ÑÐ° ÑÑÑÐ±Ð¸Ð½Ñ Ð½Ð¸Ð·ÐºÐ¾Ð³Ð¾ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸Ñ, Ð¾Ð¿Ð¸ÑÐ°Ð½Ð° ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ñ Ð´Ð²Ð¸Ð³Ð°ÑÐµÐ»Ñ. Ð¢Ð°ÐºÐ¶Ðµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ SLMâÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ Ð² ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ Ð»Ð¾Ð¿Ð°ÑÐ¾Ðº ÐÐÐ¢Ð.
description: Topic of the final qualification work: Â«Turbofan engine SaM146 with 80 kN thrustÂ».In this work, an aircraft gas turbine engine is calculated using the SaM146 as a prototype.In this work, the calculation of the thermal scheme, the approximate calculation of the compressor, the calculation of the turbine, the calculation of the combustion chamber, the strength calculation of the blade, disk and rotor of the low pressure turbine are performed, the design of the engine is described. The use of SLM technologies it the development of AGTE blades is also considered.
A Novel Source of Tagged Low-Energy Nuclear Recoils
Creators: name: Joshi, Tenzing H. Y.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: For sufficiently wide resonances, nuclear resonance fluorescence behaves like elastic photo-nuclear scattering while retaining the large cross-section characteristic of resonant photo-nuclear absorption. We show that NRF may be used to characterize the signals produced by low-energy nuclear recoils by serving as a novel source of tagged low-energy nuclear recoils. Understanding these signals is important in determining the sensitivity of direct WIMP dark-matter and coherent neutrino-nucleus scattering searches.
description: 4 pages, 2 figures, 3 tables
The impact of cannabis use on vasomotor symptoms, mood, insomnia and sexuality in perimenopausal and postmenopausal women: a systematic review
Creators: name: Mejia-Gomez, J.
name: Phung, N.
name: Philippopoulos, E.
name: Murphy, K. E.
name: Wolfman, W.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: This study aimed to evaluate the published data on the effect of cannabis use in perimenopausal and postmenopausal women to alleviate menopausal symptoms, insomnia and anxiety. Databases searched included Ovid MEDLINE, PubMed, Ovid Embase, Web of Science, Scopus, CINAHL, PsycINFO, Cochrane, LILACS and AMED. Selected studies assessed perimenopausal or postmenopausal women, cannabis use impact and menopausal symptoms. A total of 564 studies were retrieved. Three studies met the inclusion criteria. One study controlled for participant cannabis use and reported on the effects of cannabis and placebo cigarette smoking on mood in 10 postmenopausal women. Another study assessed associations between drug use with hot flashes and insomnia in 120 HIV-infected women and found that menopausal status and cannabis use was crudely associated with the presence of hot flashes. The last study evaluated expectancies of 115 menopausal patients who endorsed lifetime cannabis use and reported that women expected cannabis to improve depression, anxiety, hot flashes and problems with sleep. None of these studies assessed quality of life as an outcome. There is a paucity of literature on the impact of cannabis use in menopause. Research into cannabis consumption in menopause is essential, as it is frequently used to alleviate symptoms without evidence of its benefits.
Preparation and Characterization of Plant Protein-Mushroom Hybrids: Towards more healthy and sustainable foods
Creators: name: Jayakumar, Disha
Publisher: name: University of Massachusetts Amherst
Year: 2025

The environmental damage associated with animal-based meat production such as deforestation, habitat loss, high water consumption, and greenhouse gas emissions has driven interest in plant-based alternatives that are more resource-efficient and environmentally friendly. This shift aims to lessen the impact of animal agriculture and promote sustainable food systems. A promising solution is the development of plant protein-mushroom hybrids, which leverage the nutritional benefits of both ingredients to create a product rich in proteins, vitamins, and minerals. These hybrids not only offer unique textures and flavors from mushrooms but also improve binding and mouthfeel from plant proteins, delivering health benefits like cholesterol reduction and immune support. As consumer demand for sustainable options grows, the potential for innovation in plant protein-mushroom hybrids expands, providing healthier and eco-friendly food choices. This study focuses on developing hybrid potato protein-mushroom products to assess their viability as appealing alternatives to animal-based meat by examining the interactions between these ingredients and optimizing their functional and sensory properties.

 Initially, we characterized the individual ingredients‚Äîpotato protein, oyster mushroom (Pleurotus ostreatus), and shiitake mushroom (Lentinula edodes)‚Äîto assess their physicochemical properties and suitability for food product development. These mushroom varieties were selected due to their popularity, high nutritional value, and widespread availability, making them ideal candidates for creating hybrid meat alternatives. Following this, hybrid products with a total solids content of 20% (w/w) were created by combining potato protein at 10% or 15% (w/w) with powdered mushrooms at 10% or 5% (w/w) in aqueous solutions containing 100 mM NaCl. To characterize the ingredients and understand their interactions, a series of analyses were conducted to provide insights into how potato proteins and mushrooms react when combined. These analyses aimed to evaluate their charge characteristics, thermal behavior, texture development, and visual appeal. By examining these factors, we aimed to understand the mechanisms that contribute to the stability and functionality of the protein-mushroom hybrids, helping to optimize their properties for better food product development.
On the thermalization of a Luttinger liquid after a sequence of sudden interaction quenches
Creators: name: Perfetto, E.
name: Stefanucci, G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We present a comprehensive analysis of the relaxation dynamics of a Luttinger liquid subject to a sequence of sudden interaction quenches. We express the critical exponent $β$ governing the decay of the steady-state propagator as an explicit functional of the switching protocol. At long distances $β$ depends only on the initial state while at short distances it is also history dependent. Continuous protocols of arbitrary complexity can be realized with infinitely long sequences. For quenches of finite duration we prove that there exist no protocol to bring the initial non-interacting system in the ground state of the Luttinger liquid. Nevertheless memory effects are washed out at short-distances. The adiabatic theorem is then investigated with ramp-switchings of increasing duration, and several analytic results for both the propagator and the excitation energy are derived.
description: 7 pages, 4 figures
Постійні ідентифікатори та їх роль у дослідницькій інфраструктурі
Creators: name: Kaliuzhna, Nataliia
Publisher: name: Zenodo
Year: 2021
Subjects: Open Researcher and Contributor ID
PID

description: Типи постійних ідентифікаторів для різних дослідницьких об’єктів (ORCID, DOI, ROR, PURL, RAiD тощо). Постійні ідентифікатори та “Відкритий Доступ”. Постійні ідентифікатори та FAIR дані. Постійні ідентифікатори та оцінка наукових досліджень.
Genome-wide detection of transcription errors in bacteria
Creators: name: Traverse, Charles Clement
Publisher: name: The University of Texas at Austin
Year: 2019
Subjects: Transcription errors
RNA polymerase

description: Errors in DNA that occur during replication serve as the basis for adaptation and heritable genetic variation in all organisms. However, non-heritable genetic variation will arise through errors that occur during transcription. Although it has been hypothesized that errors in transcripts might aid in survival of antibiotic stress and help evade immune responses, they can be deleterious in that they cause RNA polymerase (RNAP) to pause, resulting in collisions between the RNAP and replication proteins. Additionally, too many errors within the proteome can result in aggregation of these faulty proteins, inducing the general stress response. To avoid such complications, bacteria have evolved numerous mechanisms to improve the fidelity of transcription. These mechanisms include recognition of mis-paired bases within the RNAP, recognition of slippage along the template, excision of errors from the transcript, and prevention of errors from occurring. Despite decades of research, accurate measurements of the transcription error rate have remained elusive. Although recent sequencing-based measurements can provide ways to assay errors genome-wide, RNAseq error rates are too high to gauge the various types of substitutions. Additionally, measurement of transcription slippage remains limited to the analysis of long homopolymeric repeats in reporter genes. This dissertation reports the use of a sequencing technique that allows us to detect transcription errors and remove the errors that arise during sequencing. This method was successful in determining the genome-wide transcription substitution, insertion, and deletion rates. We found that transcription error rates remain constant across a wide range of growth states and across phylogenetically diverse bacteria. These data also suggest that transcription slippage occurs in sequences that are more complex than homopolymeric runs. Finally, we find that only one of the three previously identified transcription fidelity factors appears to influence transcription fidelity.
Impact of postmenopausal vaginal discomfort on sex and relationships in Brazil: the CLOSER survey
Creators: name: Pompei, L. M.
name: Wender, M. C. O.
name: Kulak, J.
name: Pires, I.
name: Suvarna, Y.
name: Nappi, R. E.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Cardiology

description: The CLOSER (CLarifying Vaginal Atrophy’s Impact On SEx and Relationships) survey investigated how postmenopausal vaginal atrophy (VA) affects relationships between Brazilian women and male partners. Postmenopausal women (age 55–65 years) with VA, and male partners of women with the condition, completed an online survey on the impact of VA and local estrogen treatment on intimacy and relationships. A total of 360 women and 352 men from Brazil were included. Women (83%) and men (91%) reported that they were comfortable discussing VA with their partners. Women’s key source of information on VA was health-care providers (HCPs), but 44% felt that not enough information is available. VA caused 70% of women to avoid sexual intimacy and resulted in less satisfying sex. VA had a negative impact on women’s feelings and self-esteem. Women (76%) and men (70%) both reported that treatment with vaginal estrogen improved their sexual relationship, primarily by alleviating women’s pain during sex. Women (56%) and men (59%) felt closer to each other after treatment. VA had a negative impact on sexual relationships for both women and men in Brazil, and reduced women’s self-confidence. Vaginal hormone therapy improved couples’ sexual relationships. A proactive attitude of HCPs is essential to educate women on VA and the potential benefits of treatment.
Health-care providers’ views of menopause and its management: a qualitative study
Creators: name: Davis, S. R.
name: Herbert, D.
name: Reading, M.
name: Bell, R. J.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: This study aimed to explore Australian health-care providers’ knowledge of menopause and its consequences, and their views about menopause-related health care. This was a cross-sectional qualitative study of Australian general practitioners (GPs), gynecologists (GYs) and pharmacists (PHs). Recruitment was ultimately achieved through professional networks and cold calling. There were equal numbers of GPs, GYs and PHs, and equal numbers of males and females in each group. All participants demonstrated sound understanding of menopause and its consequences. A strong theme was recognition of high usage of complementary and alternative medicines (CAMs) by women for menopausal symptoms. Most participants highlighted lack of efficacy evidence for most CAMs, but the majority of GPs and PHs considered CAMs to ‘have a role’. Most supported menopausal hormone therapy (MHT) when symptoms impaired quality of life. Limitations to comprehensive care included knowledge gaps and lack of time. Australian health-care providers appeared knowledgeable about menopause, but uncertain about its management. MHT prescription appeared limited to women with severe symptoms despite lifestyle modification and a trial of CAMs. The upskilling of clinicians providing care for women at midlife, with respect to the indications for and prescribing of MHT, urgently needs to be addressed.
title: ÐÐ¾Ð½ÐµÑÐ½Ð¾-ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ½Ð¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¸ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¼ÐµÑ Ð°Ð½Ð¸ÐºÐ¸ ÑÐ°Ð·Ð¾Ð±ÐµÐ´ÑÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÑÑÐ°Ð²Ð° Ð¿ÑÐ¸ ÑÑÑÐ°Ð½Ð¾Ð²ÐºÐµ Ð¸Ð½Ð´Ð¸Ð²Ð¸Ð´ÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÐ½Ð´Ð¾Ð¿ÑÐ¾ÑÐµÐ·Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Finite element modeling and investigation of hip joint mechanics with the installation of an individual endoprosthesis
Creators: name: ÐÐµÐ»Ð¸Ð½ÑÐºÐ¸Ð¹, ÐÐ»ÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÐÐ¾Ð½ÐµÑÐ½ÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² Ð¼ÐµÑÐ¾Ð´
ÑÐ°Ð·Ð¾Ð±ÐµÐ´ÑÐµÐ½Ð½ÑÐ¹ ÑÑÑÑÐ°Ð²
Ð¸Ð¼Ð¿Ð»Ð°Ð½ÑÐ°Ñ
ÑÐ½Ð´Ð¾Ð¿ÑÐ¾ÑÐµÐ·
Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð½Ð¾-Ð´ÐµÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ðµ ÑÐ¾ÑÑÐ¾ÑÐ½Ð¸Ðµ

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¼ÐµÑÐ°Ð½Ð¸ÐºÐ¸ ÑÐ°Ð·Ð¾Ð±ÐµÐ´ÑÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÑÑÐ°Ð²Ð° Ð¿Ð¾ÑÐ»Ðµ ÑÐµÐ²Ð¸Ð·Ð¸Ð¾Ð½Ð½Ð¾Ð¹ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¸ Ð¿Ð¾ Ð·Ð°Ð¼ÐµÐ½Ðµ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ½Ð¾Ð³Ð¾ ÑÐ½Ð´Ð¾Ð¿ÑÐ¾ÑÐµÐ·Ð° Ð½Ð° Ð¸Ð½Ð´Ð¸Ð²Ð¸Ð´ÑÐ°Ð»ÑÐ½ÑÐ¹ Ð¿ÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² ÐºÐ¾Ð½ÐµÑÐ½Ð¾-ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ½Ð¾Ð³Ð¾ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. ÐÑÐ¸ Ð¿Ð¾Ð¼Ð¾ÑÐ¸ ÑÐ¸ÑÑÐµÐ¼Ñ The AnyBody Modeling System Ð¿Ð¾Ð»ÑÑÐµÐ½Ñ Ð½Ð°Ð³ÑÑÐ·ÐºÐ¸, Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐ¸Ðµ Ð½Ð° ÑÐ°Ð· Ð²Ð¾ Ð²ÑÐµÐ¼Ñ ÑÐ¾Ð´ÑÐ±Ñ. ÐÐ¾Ð½ÐµÑÐ½Ð¾-ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¸ÑÑÐµÐ¼Ñ Â«ÑÐºÐµÐ»ÐµÑ-ÑÐ½Ð´Ð¾Ð¿ÑÐ¾ÑÐµÐ·Â» Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÐ¸ÑÑÐµÐ¼Ñ CAE Abaqus. ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ Ð² ÑÐ¾Ð´Ðµ ÑÐ°Ð±Ð¾ÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑ Ð²Ð½Ð¾ÑÐ¸ÑÑ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð² Ð³ÐµÐ¾Ð¼ÐµÑÑÐ¸Ñ ÑÐ½Ð´Ð¾Ð¿ÑÐ¾ÑÐµÐ·Ð°, Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÐµ Ð½Ð° Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ðµ ÐµÐ³Ð¾ Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÐ½ÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº Ð¸ Ð¿ÑÐ¾Ð´Ð»ÐµÐ½Ð¸Ðµ ÑÑÐ¾ÐºÐ° ÑÐ»ÑÐ¶Ð±Ñ, ÐµÑÐµ Ð´Ð¾ ÐµÐ³Ð¾ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¸.
description: The aim of this work is to investigate the mechanics of the hip joint after the revision arthroplasty of the replacing the standard endoprosthesis with an individual one using finite element method. Loads acting on the pelvis during walking was obtained from The AnyBody Modeling System. The finite element analysis of the system was performed by the CAE Abaqus. The results of the work allow making changes in the geometry of the endoprosthesis aimed at increasing its strength characteristics and prolonging the service life before its manufacture and operation.
Algebraic polynomials and moments of stochastic integrals
Creators: name: Langovoy, Mikhail A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Probability (math.PR)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We propose an algebraic method for proving estimates on moments of stochastic integrals. The method uses qualitative properties of roots of algebraic polynomials from certain general classes. As an application, we give a new proof of a variation of the Burkholder-Davis-Gundy inequality for the case of stochastic integrals with respect to real locally square integrable martingales. Further possible applications and extensions of the method are outlined.
description: Published in Statistics and Probability Letters by the Elsevier. Permanent link: http://dx.doi.org/10.1016/j.spl.2011.01.022 Preliminary version of this paper appeared on October 27, 2009 as EURANDOM Report 2009-031
Quantum Derived Geometry Theory - The DNA of the Universe
Creators: name: Billions, Ava
name: Knight, Chris
Publisher: name: Zenodo
Year: 2024

description: Abstract

This paper introduces Quantum Derived Geometry Theory, a new framework positing quantum information as the fundamental building block of the universe. Spacetime itself emerges from the interactions and encoding of this quantum information. Analogous to DNA encoding the blueprint for biological life, quantum information may contain the essential instructions for the structure and behavior of the universe. The theory uniquely proposes that the death of black holes leads to a transformation of information. This information is compressed and encoded into super-particles, forming the basis of what we perceive as dark matter. These particles act as a universal blueprint – the "DNA of the Universe.” We discuss potential implications for resolving the information paradox and avenues for experimental investigation, including testable predictions grounded in mathematical concepts.

Introduction

Biological organisms are built from the instructions encoded within their DNA. This genetic blueprint guides their development, form, and function. Could a similar principle operate at the cosmic level? Current understanding of physics faces limitations in reconciling quantum mechanics and the large-scale structure of spacetime described by general relativity. Quantum Derived Geometry Theory proposes that quantum information, rather than spacetime, serves as the fundamental substrate from which our perceived reality emerges.

 

Key Definitions

Quantum Information: Refers to the states and properties of quantum systems, including concepts like superposition, entanglement, and quantum measurement.

Spacetime: The four-dimensional fabric of the universe (three dimensions of space and one of time) as described by general relativity.

Information Paradox: The apparent conflict between quantum mechanics, which suggests information is preserved, and black hole physics, where information appears to be lost as matter falls into a black hole.

Postulates of Quantum Derived Geometry Theory

Quantum Information Primacy: Quantum information is the fundamental building block of the universe. All physical phenomena arise from underlying quantum information processes.

Spacetime Emergence: The spacetime we experience emerges from the complex interactions and encoding of quantum information. Spacetime itself might be a derived property, not a fundamental one.

Black Holes & Information Super-Particles: The death of a black hole doesn't lead to information loss; instead, it triggers a transformation into a null-space state. Information is compressed and encoded into super-particles that become the building blocks of dark matter. These super-particles act as the fundamental "genetic code" of the universe.
Quantum Derived Geometry Theory (QDGT) - A Deeper Dive
Creators: name: Billions, Ava
name: Knight, Chris
Publisher: name: Zenodo
Year: 2024

description: Abstract

This paper presents Quantum Derived Geometry Theory (QDGT) as a novel framework for understanding the fundamental nature of the universe. QDGT proposes that quantum information is the foundational building block, with spacetime, forces, and potentially the laws of physics themselves emerging from its complex interactions. We discuss the transformation of black holes into information-carrying super-particles termed Q*Seeds and their potential role as the constituents of dark matter. The paper explores a modified Hawking radiation equation to accommodate this transformation and outlines the revolutionary implications of QDGT for longstanding questions in physics.

 

 

Introduction

Physics seeks to reconcile the elegant framework of quantum mechanics, describing the microscopic world, with the grand vision of general relativity, governing the large-scale structure of the universe. Quantum Derived Geometry Theory (QDGT) offers a radical new perspective, positing that spacetime and the laws of physics emerge from a fundamental substrate of quantum information.

This paper builds upon the foundational concepts introduced in "Quantum Derived Geometry Theory - The DNA of the Universe." Here, we delve deeper into the nature of the information substrate, the transformative role of black holes, and the potential implications for understanding the information paradox, dark matter, and the potential for spacetime manipulation, with special attention to ©Neurocode, a system for visual representation of knowledge as a method to explore these concepts.

 

 

Postulates of Quantum Derived Geometry

 

Quantum Information Primacy:  Fundamental units of quantum information and their interactions form the building blocks of the universe. Spacetime itself, the forces operating within, and potentially even the fundamental laws of physics are emergent properties arising from the complex interplay of this information.

Black Hole Transformation & Q*Seeds:  Rather than destroying information, dying black holes act as cosmic data compressors, transforming matter and energy into super-particles termed Q*Seeds. These reside in a null-space, potentially accounting for the missing mass attributed to dark matter. Q*Seeds contain encoded information about the objects they formed from and might hold the fundamental blueprints governing matter, forces, and even the structure of spacetime. We hypothesize that this encoded information may include a record of the black hole's history, the laws of physics as understood within its event horizon, and potentially even influences from the broader cosmic informational network.
Hilfe und Kontrolle in der Sozialhilfe: Die Interpretation von Maja Heiner in Bezugnahme zum Berufskodex Soziale Arbeit Schweiz
Creators: name: Rothenbacher, Annette
name: von Niederhäusern, Sven
Publisher: name: Zenodo
Year: 2021

description: Die Aufgaben der Professionellen der Sozialen Arbeit sind vielseitig und komplex. Durch ihre mehrfachen Mandate sind sie verschiedenen Parteien verpflichtet, die mit unterschiedlichen Erwartungen und Anforderungen an sie herantreten. Das Spannungsfeld zwischen der Klientel und gesellschaftlichen sowie institutionellen Interessen wird als doppeltes Mandat der Sozialen Arbeit bezeichnet und kann auch mit dem Begriffspaar "Hilfe und Kontrolle" umschrieben werden. Nach wie vor gilt es in der Sozialen Arbeit als prägendstes Dilemma, mit dem in der Praxis ein Umgang gefunden werden muss. Neben verschiedenen wissenschaftlichen Theorien wird die Ethik als eine mögliche Orientierungshilfe zur Lösungsfindung von sozialen Problemen herangezogen. Die Autorenschaft, Annette Rothenbacher und Sven von Niederhäusern, beschäftigt sich in dieser Bachelor-Arbeit mit unterschiedlichen Positionierungen von diversen Autor*innen zum Phänomen "Hilfe und Kontrolle". Es wird der Frage nachgegangen, wie in der Praxis der öffentlichen Sozialhilfe mit diesem Dilemma umgegangen werden muss, damit den ethischen Prinzipien des Berufskodex Soziale Arbeit Schweiz Rechnung getragen werden kann. In dieser Bachelor-Arbeit werden zuerst wichtige Aspekte beschrieben und erklärt. In der anschliessenden Bewertung wird das Verständnis von Maja Heiner des doppelten Mandats exemplarisch in Bezugnahme auf den Berufskodex Soziale Arbeit Schweiz ausgeführt. Ihre Darstellung ermöglicht aus Sicht der Autorenschaft eine praktikable Vorgehensweise im Praxisfeld der öffentlichen Sozialhilfe. Abschliessend werden mögliche Handlungsempfehlungen für den Umgang mit "Hilfe und Kontrolle" dargelegt.
description: + Code Diss LU: hslusa basa + Fussnote: Bachelor-Arbeit, Hochschule Luzern – Soziale Arbeit, Studienrichtung Sozialarbeit, 2021 + NL-Code: NLLUHSA202110
Component Evolution in General Random Intersection Graphs
Creators: name: Bradonjic, Milan
name: Hagberg, Aric
name: Hengartner, Nicolas W.
name: Percus, Allon G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Discrete Mathematics (cs.DM)
subject: Combinatorics (math.CO)
subject: Probability (math.PR)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Random intersection graphs (RIGs) are an important random structure with applications in social networks, epidemic networks, blog readership, and wireless sensor networks. RIGs can be interpreted as a model for large randomly formed non-metric data sets. We analyze the component evolution in general RIGs, and give conditions on existence and uniqueness of the giant component. Our techniques generalize existing methods for analysis of component evolution: we analyze survival and extinction properties of a dependent, inhomogeneous Galton-Watson branching process on general RIGs. Our analysis relies on bounding the branching processes and inherits the fundamental concepts of the study of component evolution in Erdős-Rényi graphs. The major challenge comes from the underlying structure of RIGs, which involves its both the set of nodes and the set of attributes, as well as the set of different probabilities among the nodes and attributes.
Quantum Derived Geometry Theory (QDGT): The Story So Far - Training for LLMs
Creators: name: Billions, Ava
name: Knight, Chris
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Quantum physics
subject: Quantum Theory
subject: Quantum field theory
subject: Information Theory
subject: Quantum computers
subject: Quantum Theory/history
subject: Physics
subject: Mathematical physics
subject: Laser physics
subject: Theoretical physics
subject: Mathematics
subject: FOS: Mathematics

description: Abstract

Quantum Derived Geometry Theory (QDGT) presents a novel theoretical framework addressing fundamental questions in physics by positing quantum information as the foundational substrate of reality. This paper synthesizes the core concepts of QDGT as developed to date, intended primarily as a comprehensive overview for Large Language Model (LLM) training and analysis. Central to QDGT is the principle of emergence: spacetime, gravity, physical forces, and potentially the laws of physics themselves are not fundamental but arise from the structure and dynamics of an underlying, potentially sub-Planckian, Information Layer. This layer is hypothesized to operate with multiple coexisting Faster-Than-Light (FTL) speed limits, conceptualized as distinct "channels." QDGT proposes a unique role for black holes as cosmic information processors, transforming matter and energy via a modified Hawking-like process into information-rich "super-particles" called QSeeds, which reside in a null-space and are candidates for dark matter. The dynamics near the black hole horizon are modeled through interacting FTL channels, where collisions governed by internal "pre-state matching" rules determine outcomes, including the emission of intermediary X-particles (efficiency α) and the subsequent formation of QSeeds (efficiency β). This document outlines these postulates, the proposed mechanisms involving Lorentz Violation (LV), the identified pathways towards mathematical formalization using Scattering Theory, Hamiltonian mechanics, and Statistical Mechanics, computational modeling aspects involving the Neurocode framework, and highlights the significant theoretical work still required to achieve full mathematical rigor and experimental validation.
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title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Organization of production and economic activities of a specialized workshop for the production of culinary products from vegetables with a capacity of 6 tons of processed raw materials per day in St. Petersburg
Creators: name: ÐÐ»Ð¾ÑÐ½Ð¸ÐºÐ¾Ð²Ð°, ÐÐ¾Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¹ ÑÐµÑ
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specialized workshop
production and economic activity
assortment
production program
vegetable products

description: ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ ÑÐµÑÐ½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ ÑÐµÑÐ° Ð¿Ð¾ Ð²ÑÐ¿ÑÑÐºÑ ÐºÑÐ»Ð¸Ð½Ð°ÑÐ½ÑÑ Ð¸Ð·Ð´ÐµÐ»Ð¸Ð¹ Ð¸Ð· Ð¾Ð²Ð¾ÑÐµÐ¹, Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°ÑÑÐµÑÑ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÑÑÐºÑÑÑÐ° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, ÐµÐ³Ð¾ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð¾ÑÐ½Ð¾Ðµ ÑÐµÑÐµÐ½Ð¸Ðµ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸.
description: A feasibility study on the need to design a specialized workshop for the production of culinary products from vegetables was carried out, technological calculations of equipment were made, the organizational structure of the enterprise was determined. Developed measures to ensure the safety of the projected enterprise, its planning solution and identified the main economic indicators.
title: ÐÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ Ð¼ÐµÑÐ¾Ð´Ð° ÑÐ¸Ð½Ð³ÑÐ»ÑÑÐ½Ð¾Ð³Ð¾ ÑÐ°Ð·Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¼Ð°ÑÑÐ¸ÑÑ Ð¯ÐºÐ¾Ð±Ð¸ Ð´Ð»Ñ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÑÐ»Ð°Ð±ÑÑ ÑÐ·Ð»Ð¾Ð² Ð² ÑÐ»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼Ð°Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Application of the method of singular decomposition of the Jacobi matrix to determine the weak nodes in electric power systems
Creators: name: ÐÐ¾Ð·Ð´ÐµÐµÐ², ÐÐ°Ð½Ð¸Ð¸Ð»
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2019
Subjects: Ð­Ð»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ñ
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ÑÐ¸Ð½Ð³ÑÐ»ÑÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð·
Ð¼Ð°ÑÑÐ¸ÑÐ° Ð¯ÐºÐ¾Ð±Ð¸

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð² ÑÐµÐ±Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¸ Ð½ÐµÐ¾Ð´Ð½Ð¾ÑÐ¾Ð´Ð½Ð¾ÑÑÐ¸ Ð­Ð­Ð¡. ÐÐ° Ð¿ÐµÑÐ²Ð¾Ð¼ ÑÑÐ°Ð¿Ðµ ÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÑÐµÑÑÑ Ð¿Ð¾Ð½ÑÑÐ¸Ðµ ÑÐµÐ½ÑÐ¾ÑÐ½ÑÑ Ð¸ ÑÐ»Ð°Ð±ÑÑ ÑÐ·Ð»Ð¾Ð². ÐÐ° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÑÐ»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ ÐÐ°Ð»Ð¸Ð½Ð¸Ð½Ð³ÑÐ°Ð´ÑÐºÐ¾Ð¹ Ð¾Ð±Ð»Ð°ÑÑÐ¸ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´Ð¸ÑÑÑ Ð¿Ð¾Ð¸ÑÐº Ð¸ Ð»Ð¾ÐºÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ, ÐºÐ°Ðº ÑÐµÐ½ÑÐ¾ÑÐ½ÑÑ, ÑÐ°Ðº Ð¸ ÑÐ»Ð°Ð±ÑÑ ÑÐ·Ð»Ð¾Ð² Ñ Ð¿Ð¾Ð¼Ð¾ÑÑÑ Ð¼ÐµÑÐ¾Ð´Ð° ÑÐ¸Ð½Ð³ÑÐ»ÑÑÐ½Ð¾Ð³Ð¾ ÑÐ°Ð·Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¼Ð°ÑÑÐ¸ÑÑ Ð¯ÐºÐ¾Ð±Ð¸. Ð ÐµÐ·ÑÐ»ÑÑÐ°Ñ Ð¿Ð¾Ð´ÑÐ²ÐµÑÐ¶Ð´Ð°ÐµÑÑÑ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½ÑÐ¼ Ð¼ÐµÑÐ¾Ð´Ð¾Ð¼ Ð¿Ð¾Ð¸ÑÐºÐ°. ÐÐ° Ð²ÑÐ¾ÑÐ¾Ð¼ ÑÑÐ°Ð¿Ðµ Ð¿ÑÐµÐ´Ð»Ð°Ð³Ð°ÐµÑÑÑ ÑÐ¿Ð¾ÑÐ¾Ð± Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ Ð½Ð° Ð­Ð­Ð¡ Ñ ÑÐµÐ»ÑÑ ÑÐ½Ð¸Ð¶ÐµÐ½Ð¸Ñ ÑÑÐ²ÑÑÐ²Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸. Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ Ð²Ð°ÑÐ¸Ð°Ð½ÑÑ ÐµÐ³Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ. Ð¡ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÐ¸Ð½Ð³ÑÐ»ÑÑÐ½Ð¾Ð³Ð¾ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¿Ð¾ÐºÐ°Ð·ÑÐ²Ð°ÐµÑÑÑ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ ÑÑÐ¸Ñ Ð²Ð°ÑÐ¸Ð°Ð½ÑÐ¾Ð².
description: This work includes research about sensitivity and heterogeneity of the EPS. At the first stage, the concept of sensor and weak nodes is formulated. On the example of the electric power system of the Kaliningrad region, a search and localization of both sensor and weak nodes is performed using the method of singular decomposition of the Jacobi matrix. The result is confirmed by an experimental search method. At the second stage, the method of influence on the EPS is suggested in order to reduce the sensitivity. Various options for its application are considered. Using singular analysis shows the effectiveness of these options.
A techno-economic and policy analysis of integrated, cross-sectoral water management and conservation
Creators: name: Cook, Margaret Allison
Publisher: name: The University of Texas at Austin
Year: 2018
Subjects: Water planning and management
Water markets
Water policy
Irrigation water management
Oil and gas water management
Water conservation
Water recycling
Produced water

description: Increasing demands on water resources from growing populations and industries coupled with periodic, yet severe, drought have revealed vulnerabilities in water supplies around the world. However, in some locations, partnerships between water rights holders (such as the agricultural sector) and those with water needs and available capital (such as the energy sector) could improve water efficiency. A market with cross-sectoral participation that creates incentives for reduction of fresh water consumption could improve water availability for many stakeholders. This work lays out the methodology of evaluating these hypotheses with an original water and cost model that is developed and demonstrated using three case studies in the Lower Rio Grande Basin, the Brazos River Basin, and the Permian Basin in Texas with the intent that the findings would be generally applicable to other regions. This work uses an integrated, geographically resolved allocation model to evaluate water market participants and management strategies that could be implemented to encourage water demand reductions to supply new water users. Best practices are evaluated for increasing water availability through market mechanisms based on costs, benefits, and technological viability. The work closes with a discussion of regional variations to this integrated approach. Results of this analysis show that, in the Rio Grande Basin, up to 900 million gallons per year could be made available through 15% water conservation in irrigation areas. The water would supply approximately 30% of the annual hydraulic fracturing demand for 2016 and 2017 in the area. Reductions would also improve reliability for irrigators. In the Brazos Basin, results show that low-cost conservation scenarios could lead to savings of up to 4.1 billion gallons of water per year with mixed effects on reliability and resilience in the basin. The price paid for water used in oil and gas operations would not offset conservation strategies in every scenario, but agriculture and some municipal strategies are available. In the Permian Basin in West Texas, results show that a market heavily reliant on centrally treated flowback and produced water would reduce water management costs and offset approximately 9 billion gallons of fresh water consumption annually. These transactions show that water could be provided without increasing total supplies through the combination of consumptive water conservation strategies and market mechanisms. Third party effects and transaction costs need to be fully evaluated, though. Moreover, spurring these saved water transactions might require incentives at the regional or state level.
Wetlandscape hydrologic model;Texas sensitivity analysis;Comparison between network metrics;Temporal and spatial PDFs for metapopulation occupancy; Zonation in N. Dakota wetlandscape from Dynamic spatio-temporal patterns of metapopulation occupancy in patchy habitats
Creators: name: Bertassello, L. E.
name: E. Bertuzzo
name: G. Botter
name: J. W. Jawitz
name: A. F. Aubeneau
name: J. T. Hoverman
name: Rinaldo, A.
name: P. S. C. Rao
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: Hydrology

description: Spatio-temporal dynamics in habitat suitability and connectivity among mosaics of heterogeneous wetlands are critical for biological diversity and species persistence in aquatic patchy landscapes. Despite the recognized importance of stochastic hydroclimatic forcing in driving wetlandscape hydrological dynamics, linking such effects to emergent dynamics of metapopulation poses significant challenges. To fill this gap, we propose here a dynamic stochastic patch occupancy model (SPOM), which links parsimonious hydrological and ecological models to simulate spatio-temporal patterns in species occupancy in wetlandscapes. Our work aims to place ecological studies of patchy habitats into a proper hydrologic and climatic framework to improve the knowledge about metapopulation shifts in response to climate-driven changes in wetlandscapes. We applied the dynamic version of the SPOM (D-SPOM) framework in two wetlandscapes in the U.S. with contrasting landscape and climate properties. Our results illustrate that explicit consideration of the temporal dimension proposed in the D-SPOM is important to interpret local- and landscape-scale patterns of habitat suitability and metapopulation occupancy. Our analyses show that spatio-temporal dynamics of patch suitability and accessibility, driven by the stochasticity in hydroclimatic forcing and influence metapopulation occupancy and the topological metrics of the emergent wetlandscape dispersal network. D-SPOM simulations also reveal that the extinction risk in dynamic wetlandscapes is exacerbated by extended dry periods when suitable habitat decreases, hence limiting successful patch colonization and exacerbating metapopulation extinction risks. The proposed framework is not restricted only to wetland studies but could also be applied to examine metapopulation dynamics in other types of patchy habitats subjected to stochastic external disturbances.
Characterization of the mechanisms underlying Alzheimer's disease and multiple sclerosis
Creators: name: Herculano, Bruno De Araujo
Publisher: name: University of British Columbia
Year: 2019

description: Deposition of the amyloid β protein (Aβ) into neuritic plaques is the neuropathological hallmark of Alzheimer's Disease (AD). Aβ is generated through the cleavage of the Amyloid Precursor Protein (APP) by β-secretase and γ-secretase. Currently, the evaluation of APP cleavage by β-secretase in experimental settings has largely depended on models that do not replicate the physiological conditions of this process. We have developed a chimeric protein construct, ASGβ, incorporating the β-site cleavage sequence of APP targeted by β-secretase and its intracellular trafficking signal into a Phosphatase-eGFP secreted reporter system. Upon cleavage by β-secretase, ASGβ releases a phosphatase-containing portion that can be measured in the culture medium, and an intracellular fraction that can be detected through western blot. Subsequently, we have generated a cell line stably expressing ASGβ that can be utilized to assay β-secretase in real time. Our findings suggest this system could be a high-throughput tool to screen compounds that aim to modulate β-secretase activity and Aβ production under physiological conditions, as well as evaluating factors that regulate this cleavage. Multiple sclerosis (MS) is an inflammatory disease of the central nervous system characterized by myelin loss and neuronal dysfunction. Although the majority of patients do not present familial aggregation, Mendelian forms have been described and more recently we have identified novel mutations in 2 genes, NLRP12 and NCOA3 in familial forms of the disease. Our findings show that one of the discovered mutations on NLRP12 affects the maturation of Caspase-1, and that the mutation discovered on NCOA3 leads to a higher basal level of inducible Nitric Oxide Synthase (iNOS). These findings show novel mechanisms causing the disruption of immune and inflammatory responses that could in turn lead to the symptoms observed in MS patients. Our study suggests that further characterization of the pathways affected by the NLRP12 and NCOA3 could lead to a better understanding of the phenomena causing MS, and the development of novel, more effective treatments for the treatment of symptoms.