cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ
Creators: name: Hashioka, Sadayuki
name: Klegeris, Andis
name: McGeer, Patrick L
Publisher: name: BioMed Central
Year: 2015

description: Backgrounds: Increasing evidence shows that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) possesses potent anti-inflammatory and immunomodulatory properties. It is tempting to evaluate the potential of SAHA as a therapeutic agent in various neuroinflammatory and neurodegenerative disorders. Methods We examined the effects of SAHA on interferon (IFN)-γ-induced neurotoxicity of human astrocytes and on IFN-γ-induced phosphorylation of signal transducer and activator of transcription (STAT) 3 in human astrocytes. We also studied the effects of SAHA on the astrocytic production of two representative IFN-γ-inducible inflammatory molecules, namely IFN-γ-inducible T cell α chemoattractant (I-TAC) and intercellular adhesion molecule-1 (ICAM-1). Results SAHA significantly attenuated the toxicity of astrocytes activated by IFN-γ towards SH-SY5Y human neuronal cells. In the IFN-γ-activated astrocytes, SAHA reduced the STAT3 phosphorylation. SAHA also inhibited the IFN-γ-induced astrocytic production of I-TAC, but not ICAM-1. These results indicate that SAHA suppresses IFN-γ-induced neurotoxicity of human astrocytes through inhibition of the STAT3 signaling pathway. Conclusion Due to its anti-neurotoxic and anti-inflammatory properties, SAHA appears to have the therapeutic or preventive potential for a wide range of neuroinflammatory disorders associated with activated astrocytes.
title: Mail de Philippe Poussier à J. Leibowitch, transféré à Adrien Henni
Creators: name: Poussier, Philippe
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/Calames-2019311113191749
SVR Hongkong
Creators: name: Schucher, Günter
Publisher: name: China aktuell
Year: 2020

description: Wie Hongkonger Quellen berichteten, übte Staats- und Parteichef Hu Jintao erstmals öffentlich Kritik am Hongkonger Regierungschef (Chief Executive) Tung Chee-hwa, als beide anlässlich der Feierlichkeiten zum fünften Jahrestag der Rückgabe der Sonderverwaltungsregion (SVR) Macau an die VR China am 20. Dezember in Macau zusammentrafen.
description: China aktuell, China aktuell - Dezember 2004
Eumops bonariensis
Creators: name: Miretzki, Michel
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Molossidae
Eumops
Eumops bonariensis

description: Eumops bonariensis (Peters, 1874)
Distribuição Geral: do México até nordeste do Peru, norte da Argentina, Brasil e Uruguai.
Distribuição no Paraná: regiões sul, leste e noroeste (Figura 18B).
Registros: Douradina (MHNCI, 1); Portão (MHNCI, 1); União da Vitória (MHNCI, 5).
Distribuição no Paraná: regiões norte e leste, incluindo planície litorânea (Figura 19A).
 Registros: Cambé (Taddei et al., 1976); Campus da Universidade Estadual de Londrina (Lima & Reis, 1994); Laranja Azeda (MHNCI, 1); Parque Estadual Mata dos Godoy (Sekiama, 1996).
description: Published as part of Miretzki, Michel, 2003, Morcegos Do Estado Do Paraná, Brasil (Mammalia, Chiroptera): Riqueza De Espécies, Distribuição E Síntese Do Conhecimento Atual M M Abstract, pp. 101-138 in Papéis Avulsos de Zoologia (São Paulo) (São Paulo) 43 (6) on pages 116-117, DOI: 10.1590/S0031-10492003000600001, http://zenodo.org/record/13226416
Molossus ater E. Geoffroy 1805
Creators: name: Miretzki, Michel
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Molossidae
Molossus
Molossus ater

description: Molossus ater E. Geoffroy, 1805
Distribuição Geral: do México ao Peru, Guianas, Paraguai, norte da Argentina e Brasil.
Distribuição no Paraná: amplamente distribuído, exceto região centro-sul (Figura 19B).
 Registros: Adrianópolis (MHNCI, 4); Arapoti (MHNCI, 1); Bairro Alto (MHNCI, 1); Campus da Universidade Estadual de Londrina (Reis et al., 1993); Estação Ecológica do Caiuá (MHNCI, 1); fazenda Santa Isabel (MHNCI, 1); Guaratuba/Garuva (MHNCI, 2); Palotina (MHNCI, 1); rio Preto (MHNCI, 2); São João do Ivaí (MHNCI, 1).
description: Published as part of Miretzki, Michel, 2003, Morcegos Do Estado Do Paraná, Brasil (Mammalia, Chiroptera): Riqueza De Espécies, Distribuição E Síntese Do Conhecimento Atual M M Abstract, pp. 101-138 in Papéis Avulsos de Zoologia (São Paulo) (São Paulo) 43 (6) on page 118, DOI: 10.1590/S0031-10492003000600001, http://zenodo.org/record/13226416
Risk of nonaccidental and cardiovascular mortality in relation to long-term exposure to low concentrations of fine particulate matter : a Canadian national-level cohort study
Creators: name: Crouse, Dan L.
name: Peters, Paul A.
name: Van Donkelaar, Aaron
name: Goldberg, Mark S.
name: Villeneuve, Paul J.
name: Brion, Orly
name: Khan, Saeeda
name: Atari, Dominic Odwa
name: Jerrett, Michael
name: Pope III, C. Arden
name: Brauer, Michael (Of University Of British Columbia)
name: Brook, Jeffrey R.
name: Martin, Randall V.
name: Stieb, David M.
name: Burnett, Richard T.
Publisher: name: The University of British Columbia
Year: 2015

description: Background: Few cohort studies have evaluated the risk of mortality associated with long-term exposure to fine particulate matter [≤ 2.5 μm in aerodynamic diameter (PM₂.₅)]. This is the first national-level cohort study to investigate these risks in Canada. Objective: We investigated the association between long-term exposure to ambient PM₂.₅ and cardiovascular mortality in nonimmigrant Canadian adults. Methods: We assigned estimates of exposure to ambient PM₂.₅ derived from satellite observations to a cohort of 2.1 million Canadian adults who in 1991 were among the 20% of the population mandated to provide detailed census data. We identified deaths occurring between 1991 and 2001 through record linkage. We calculated hazard ratios (HRs) and 95% confidence intervals (CIs) adjusted for available individual-level and contextual covariates using both standard Cox proportional survival models and nested, spatial random-effects survival models. Results: Using standard Cox models, we calculated HRs of 1.15 (95% CI: 1.13, 1.16) from nonaccidental causes and 1.31 (95% CI: 1.27, 1.35) from ischemic heart disease for each 10-μg/m³ increase in concentrations of PM₂.₅. Using spatial random-effects models controlling for the same variables, we calculated HRs of 1.10 (95% CI: 1.05, 1.15) and 1.30 (95% CI: 1.18, 1.43), respectively. We found similar associations between nonaccidental mortality and PM₂.₅ based on satellite-derived estimates and ground-based measurements in a subanalysis of subjects in 11 cities. Conclusions: In this large national cohort of nonimmigrant Canadians, mortality was associated with long-term exposure to PM₂.₅. Associations were observed with exposures to PM₂.₅ at concentrations that were predominantly lower (mean, 8.7 μg/m³; interquartile range, 6.2 μg/m³) than those reported previously.
Der Weg des „chinesischen Rechtsstaats“: In neuen Schuhen auf alten Pfaden?
Creators: name: Heuser, Robert
Publisher: name: China aktuell
Year: 2020

description: Seitdem in China Gesetzgebung und Rechtswissenschaft blühen, stellen westliche Beobachter gerne die Frage, ob man dort auf dem Weg sei, einen Rechtsstaat zu errichten. Wer so fragt, tritt mit einem Messgerät an chinesische Entwicklungen heran, das die Ergebnisse von 200 Jahren politischen und sozialen Wandels Europas sichtbar macht. Auf dieser Messlatte finden sich Markierungen, die eine zunehmende Bändigung staatlicher Willkür zum Ausdruck bringen: zuerst das Gebot der Gesetzmäßigkeit staatlichen Handelns, zunächst vorrangig die strafrichterliche Bindung an das Gesetz, wofür zu Beginn des 19. Jahrhunderts die Wendung nulla poena sine lege gefunden wurde. Das Strafgesetz wurde so nicht nur zur Quelle, sondern auch zur Schranke des Strafens. Dies umfasst auch die Beschränkung der staatlichen Strafgewalt durch die Tat, d.h. Bestrafung ohne Ansehen der Person allein nach Maßgabe des verwirklichten gesetzlichen Tatbestands.
description: China aktuell, China aktuell - November 2004
Investitionsboom in China - Strohfeuer oder Langzeitperspektive
Creators: name: Reisach, Ulrike
Publisher: name: China aktuell
Year: 2020

description: Mit dem Beitritt zur Welthandelsorganisation WTO im Dezember 2001 wurde China zum weltweit führenden Zielland für Direktinvestitionen. Im Jahr 2003 flössen mehr als 55 Mrd. US-Dollar nach China - das sind erheblich mehr als beim bisherigen Zielland Nr. 1, den USA, und dem Weltranglisten-Fünften Deutschland. Im Jahr 2004 steigen die Direktinvestitionen voraussichtlich auf 67 Mrd. US-Dollar, 2005 werden, wenn der Boom anhält, sogar mehr als 70 Mrd. US-Dollar nach China fließen. Rund 20 Mio. Chinesen sind in einem der etwa 400.000 auslandsinvestierten Unternehmen tätig, die inzwischen fast die Hälfte der chinesischen Exporterlöse erwirtschaften.
description: China aktuell, China aktuell - November 2004
Von der wirtschaftlichen und sozialen Integration zur politischen Entspannung? Zu den Perspektiven der chinesisch-taiwanesischen Beziehungen
Creators: name: Schucher, Günter
Publisher: name: China aktuell
Year: 2020

description: Als der chinesische Staats- und Parteichef Hu Jintao am 19. September 2004 seinen Vorgänger Jiang Zemin im Vorsitz der Zentralen Militärkommission (ZMK) ablöste, entstanden damit auch Spekulationen, ob dies zu einem Wechsel in der Taiwanpolitik führen könnte. Während die einen auf eine eventuell konstruktivere Haltung hoffen, heben andere mit Blick auf die angespannte Lage hervor, dass sich die Politik verhärten werde.
description: China aktuell, China aktuell - November 2004
SVR Macau
Creators: name: Jen-Kai, Liu
Publisher: name: China aktuell
Year: 2020

description: Regierungschef Edmund Ho gab am 16. November vor der Gesetzgebenden Versammlung seine Regierungserklärung für das fiskalische Jahr 2005 (fiskalisches = Kalenderjahr) ab. Es war seine sechste Regierungserklärung und die erste nach seiner Wiederwahl Ende August. Ihr schloss sich eine Pressekonferenz an. Am Nachmittag des folgenden Tages stand Ho Mitgliedern der Gesetzgebenden Versammlung drei Stunden lang Rede und Antwort.
description: China aktuell, China aktuell - November 2004
SVR Hongkong
Creators: name: Willmann, Katrin
Publisher: name: China aktuell
Year: 2020

description: Trotz der wiederholten expliziten Absage durch Regierungschef (Chief Executive) Tung Chee-hwa und trotz scharfer Kritik durch Gao Siren, dem Direktor des chinesischen Verbindungsbüros in Hongkong, tritt das pro-demokratische Parteienlager nicht von seiner Forderung nach einem Referendum zur Einführung allgemeiner Direktwahlen bis 2007/08 in der SVR Hongkong zurück.
description: China aktuell, China aktuell - November 2004
Estimated Global Mortality Attributable to Smoke from Landscape Fires
Creators: name: Johnston, Fay H.
name: Henderson, Sarah B.
name: Chen, Yang
name: Randerson, James T.
name: Marlier, Miriam
name: DeFries, Ruth S.
name: Kinney, Patrick
name: Bowman, David M. J. S.
name: Brauer, Michael (Of University Of British Columbia)
Publisher: name: The University of British Columbia
Year: 2015

description: BACKGROUND: Forest, grass, and peat fires release approximately 2 petagrams of carbon into the atmosphere each year, influencing weather, climate, and air quality. OBJECTIVE: We estimated the annual global mortality attributable to landscape fire smoke (LFS). METHODS: Daily and annual exposure to particulate matter ≤ 2.5 μm in aerodynamic diameter (PM₂.₅) from fire emissions was estimated globally for 1997 through 2006 by combining outputs from a chemical transport model with satellite-based observations of aerosol optical depth. In World Health Organization (WHO) subregions classified as sporadically affected, the daily burden of mortality was estimated using previously published concentration–response coefficients for the association between short-term elevations in PM₂.₅ from LFS (contrasted with 0 μg/m³ from LFS) and all-cause mortality. In subregions classified as chronically affected, the annual burden of mortality was estimated using the American Cancer Society study coefficient for the association between long-term PM₂.₅ exposure and all-cause mortality. The annual average PM₂.₅ estimates were contrasted with theoretical minimum (counterfactual) concentrations in each chronically affected subregion. Sensitivity of mortality estimates to different exposure assessments, counterfactual estimates, and concentration–response functions was evaluated. Strong La Niña and El Niño years were compared to assess the influence of interannual climatic variability. RESULTS: Our principal estimate for the average mortality attributable to LFS exposure was 339,000 deaths annually. In sensitivity analyses the interquartile range of all tested estimates was 260,000–600,000. The regions most affected were sub-Saharan Africa (157,000) and Southeast Asia (110,000). Estimated annual mortality during La Niña was 262,000, compared with 532,000 during El Niño. CONCLUSIONS: Fire emissions are an important contributor to global mortality. Adverse health outcomes associated with LFS could be substantially reduced by curtailing burning of tropical rainforests, which rarely burn naturally. The large estimated influence of El Niño suggests a relationship between climate and the burden of mortality attributable to LFS.
2008 Beijing Olympic Torch Relay: Chinese and Western Narratives
Creators: name: Edney, Kingsley
Publisher: name: China aktuell
Year: 2020

description: This article investigates the events of the Olympic flame’s international journey leading up to the 2008 Beijing Olympic Games. It focuses on the symbolism of the torch relay and argues that rather than serving as a symbol of international unity and harmony, the relay has strengthened both the Chinese national narrative of victimisation at the hands of foreign powers and the Western narrative of an authoritarian and illiberal China. The article also notes that the response by some overseas Chinese to the attacks on the torch have undermined attempts to use the Olympics to boost the country’s international image, and that these overseas displays of nationalism represent a potential future problem for the Chinese Communist Party (CCP).
description: China aktuell, China aktuell - 2/2008
China Is Big News! - International Media Relations by Multinational Enterprises in China
Creators: name: Huber, Sebastian
Publisher: name: China aktuell
Year: 2020

description: In the build-up to the Beijing 2008 Olympics, the role of international media reporting from China is becoming widely apparent. Increasing media reports from China since its admission to the WTO in 2001 are both a threat and an opportunity for multinational enterprises (MNEs) on location. Their China activities are frequently in the spotlight of the international media. This paper aims at understanding the significance, dimensions and basic concepts of media relations with the international media in China from the perspective of multinational enterprises based in the People’s Republic. It investigates whether and why China’s relations with the international media differ from those of other countries, taking into account the media relations research and local market particularities while exploring best practices amongst ten MNEs in case studies. Many media relations concepts applied elsewhere could also be validated for the Chinese market. The need for a strategy in international media relations for China has emerged as one of the key findings. (Manuscript received March 11, 2008; accepted for publication April 22, 2008)
description: China aktuell, China aktuell - 2/2008
Football, Nationalism, and Fan Violence in China
Creators: name: Bridges, Brian
Publisher: name: China aktuell
Year: 2020

description: The linkages between football, nationalism and spectator violence in- China are analysed by discussing the reactions of the Chinese to two footballing defeats: the World Cup qualifying loss to Hong Kong in 1985 and the loss to Japan in the 2004 Asian Cup final. Using both political science and sociological perspectives, the settings of the two games and the violent post-match reactions of the Chinese fans are examined within a comparative framework against the background of Chinese nationalism, China’s complex relationships with Hong Kong and Japan at the time of the two games, and the significance of sport (and football in particular) in Chinese popular and governmental perspectives. The article argues that while the concept of hooliganism might best explain the 1985 events, nationalism provides greater insight into the 2004 events. (Manuscript received January 22, 2008; accepted for publication April 23, 2008)
description: China aktuell, China aktuell - 2/2008
"Actually Existing" Olympism - The Beijing 2008 Games and China´s Neoliberal Project
Creators: name: Smith, Christopher J.
name: Himmelfarb, Katie M.G.
Publisher: name: China aktuell
Year: 2020

description: The 2008 Beijing Olympic Games have been the subject of much speculation because of the Olympic movement’s purported compatibility with the promotion of universal human rights, the elimination of discrimination, and international peace. The powerful ideology of “Olympism” has much in common with the increasingly widespread phenomenon of neoliberalism, including a focus on “mega-events” and projects; a shared vocabulary of individual liberty, competition, and achievement; and an uneven record in promoting such values in reality. This paper outlines an agenda for a multi-scalar evaluation of the effect of the Beijing Games, focusing on some of the likely geographical impacts and the potential they have to influence social justice, as understood in spatial terms. (Manuscript received November 2, 2007; accepted for publication March 28, 2008)
description: China aktuell, China aktuell - 2/2008
Beijing Olympics and the Art of Nation-State Maintenance
Creators: name: De Kloet, Jeroen
name: Chong, Gladys Pak Lei
name: Liu, Wei
Publisher: name: China aktuell
Year: 2020

description: This article maps out how different actors are involved in the promotion and mediation of the Olympics. It looks at the roles of, first, the nation-state, through an analysis of the promotional materials; second, the art world and global companies, through an analysis of the touring exhibition “Sport in Art” and the Beijing art district 798; and third, the Western press and activists, through a brief analysis of the critique of the Games in the Netherlands and the Chinese response to that critique. Our analysis shows that the imageries promoting the Games are never fully under control of their producers. The Beijing Olympics, we argue, should be perceived as a field of contestation, in which conflicting discourses, constituted by different regimes of truth produced by distinct interest groups, vie for global attention. (Manuscript received February 25, 2008; accepted for publication April 1, 2008)
description: China aktuell, China aktuell - 2/2008
China sucht nach mehr Einfluss in Lateinamerika - Taiwan kämpft um die Aufrechterhaltung seiner diplomatischen Anerkennung
Creators: name: Cieslik, Thomas
Publisher: name: China aktuell
Year: 2020

description: Die Republik China (Taiwan) verliert kontinuierlich an diplomatischer Anerkennung. Aktuell unterhält sie nur noch mit 26 Staaten diplomatische Beziehungen. Darunter sind 13 von 33 lateinamerikanischen und karibischen Staaten: die karibischen Inseln wie die Dominikanische Republik, Grenada, Haiti, St. Kitts & Nevis sowie St. Vincent & Grenadinen, ferner alle mittelamerikanischen Länder (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama) und als einziges südamerikanisches Land Paraguay. Doch auch in diesen Ländern spielt die Volksrepublik China wirtschaftlich eine immer größere Rolle. Dieser Artikel beleuchtet die Außenpolitik Taiwans in Lateinamerika und stellt den Versuch der Volksrepublik China dar, diplomatische Beziehungen aufzunehmen, um langfristig ihre Position in Lateinamerika aus geostrategischen Motiven zu stärken.
description: China aktuell, China aktuell - Oktober 2004
title: Secteur d'assainissement du Rharb. Etude d'aménagement rural
title: Secteur d'assainissement du Rharb. Etude d'aménagement rural
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Assainissement

description: Cartographie
description: BESM-carto_1955-64-p593_64-05
description: 593
description: 64
description: Bulletin économique et social du Maroc
description: Source: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Source: Bulletin économique et social du Maroc
description: Source: Bulletin économique et social du Maroc (BESM) > BESM (Cartographie)
description: Relation: https://cinumed.mmsh.univ-aix.fr/idurl/1/81856
description: Coverage: Maroc
description: Coverage: Gharb
description: Coverage: XXe siècle
description: Temporal: XXe siècle
description: Bibliographic citation: « Secteur d'assainissement du Rharb. Etude d'aménagement rural », In Bulletin économique et social du Maroc (BESM), n° 64, 1955
description: Provenance: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Provenance: https://cinumed.mmsh.univ-aix.fr/
„Reverse Brain Drain“ - Das Werben der chinesischen Regierung um die Auslandsstudenten
Creators: name: Klemm, Birte
Publisher: name: China aktuell
Year: 2020

description: Seit Beginn der Reform- und Öffnungspolitik misst die chinesische Regierung den im Ausland ausgebildeten Studenten und Akademikern eine bedeutende Rolle für die sozioökonomische Entwicklung des Landes bei. So wurden nach jahrzehntelanger Isolierung 1978 erstmals wieder chinesische Studenten in großer Zahl zum Studium auch ins westliche Ausland geschickt.1 Das vordringliche Ziel bestand in einem selektiven Wissens- und Technologietransfer zur Umsetzung der ehrgeizigen Modernisierungspläne des Landes. Schon nach kurzer Zeit wurden die Erfolge und Beiträge der aus dem Ausland zurückgekehrten Studenten gefeiert.
description: China aktuell, China aktuell - Oktober 2004
title: Sicher, sauber, selbstbestimmt?
title: Kommunikationsstrategien in Stellenanzeigern aus dem japanischen Rotlichtmilieu
titleType: Subtitle
Creators: name: Göhlert, Christian
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2020

description: (Paper includes an english summary.) Job advertisements for a variety of jobs that could be broadly classified as sex work – ranging from positions as hostesses, models, and video chat operators to what amounts to outright prostitution – exist both as free magazines and in the form of websites. The former are a surprisingly common sight in Japan. Euphemistically called 高収入求人マガジン ('magazines that advertise high- paying jobs'), they can be found around subway stations, hotels and restaurants and are generally available free of charge. Besides the advertisements themselves, they usually feature various articles aimed at girls and young women and are modelled after fashion and lifestyle magazines. This paper summarizes the results of a small-scale research project that was conducted with students of the Japan Center of LMU Munich in the winter of 2016 to familiarize the participants with the basics of content analysis. The goal of the project was to identify recurring themes and patterns in six issues each of two such magazines, Momoco and Shaleo, which were collected in Tokyo between July and December 2014. In addition to the ads themselves, both magazines feature editorial contents comprising a varied selection of articles, comics, and monthly columns.
РОЛЬ СОЦИАЛЬНО-ФИЛОСОФСКИХ ВЗГЛЯДОВ ДЖАДИДОВ В СОЦИАЛЬНОЙ СТАБИЛЬНОСТИ ОБЩЕСТВА
Creators: name: Пулатов, К.А.
Publisher: name: Zenodo
Year: 2024

description: В данной статье рассматривается роль социально-философских взглядов джадидов в обеспечении социальной стабильности общества. Анализируются основные идеи джадидизма, такие как модернизация образования, приобщение к достижениям науки и техники, активное участие в общественной жизни, и демонстрируется, как эти идеи могут способствовать социальной стабильности. Особое внимание уделяется тому, как джадидизм может помочь предотвратить религиозный экстремизм и радикализм.
Evaluating quality of care for patients with type 2 diabetes using electronic health record information in Mexico
Creators: name: Pérez-Cuevas, Ricardo
name: Doubova, Svetlana V.
name: Suarez-Ortega, Magdalena
name: Law, Michael R.
name: Pande, Aakanksha H.
name: Escobedo, Jorge
name: Espinosa-Larrañaga, Francisco
name: Ross-Degnan, Dennis
name: Wagner, Anita K.
Publisher: name: BioMed Central
Year: 2015

description: Background. Several low and middle-income countries are implementing electronic health records (EHR). In the near future, EHRs could become an efficient tool to evaluate healthcare performance if appropriate indicators are developed. The aims of this study are: a) to develop quality of care indicators (QCIs) for type 2 diabetes (T2DM) in the Mexican Institute of Social Security (IMSS) health system; b) to determine the feasibility of constructing QCIs using the IMSS EHR data; and c) to evaluate the quality of care (QC) provided to IMSS patients with T2DM. Methods We used a three-stage mixed methods approach: a) development of QCIs following the RAND-UCLA method; b) EHR data extraction and construction of indicators; c) QC evaluation using EHR data from 25,130 T2DM patients who received care in 2009. Results We developed 18 QCIs, of which 14 were possible to construct using available EHR data. QCIs comprised both process of care and health outcomes. Several flaws in the EHR design and quality of data were identified. The indicators of process and outcomes of care suggested areas for improvement. For example, only 13.0% of patients were referred to an ophthalmologist; 3.9% received nutritional counseling; 63.2% of overweight/obese patients were prescribed metformin, and only 23% had HbA1c <7% (or plasma glucose ≤130 mg/dl). Conclusions EHR data can be used to evaluate QC. The results identified both strengths and weaknesses in the electronic information system as well as in the process and outcomes of T2DM care at IMSS. This information can be used to guide targeted interventions to improve QC.
SVR Macau
Creators: name: Jen-Kai, Liu
Publisher: name: China aktuell
Year: 2020

description: Macaus Tourismusindustrie boomt ungebremst. Der Besucherrekord von 11,88 Mio. im letzten Jahr wurde bereits in den ersten neun Monaten dieses Jahres übertroffen. 12,19 Mio. Touristen und damit 45,3% mehr als im Vergleichszeitraum 2003 kamen bis Ende September nach Macau. Besucher vom Festland stellten mit 57,1% die Mehrheit. 6,95 Mio. Touristen vom Festland wurden gezählt, 82,7% (!) mehr als in der entsprechenden Zeit des Vorjahres.
description: China aktuell, China aktuell - Oktober 2004
SVR Hongkong
Creators: name: Schucher, Günter
Publisher: name: China aktuell
Year: 2020

description: Die öffentlichen Konsultationen zum dritten Bericht der Taskforce für konstitutionelle Entwicklung unter Chief Secretary Donald Tsang wurden nach nunmehr fünf Monaten am 15. Oktober abgeschlossen. In ihrem Bericht hatte die Taskforce am 11. Mai d.J. Vorschläge zu Modifikationen des bestehenden Wahlrechts vorgelegt, auf deren Grundlage bis zum 31. August öffentliche Konsultationen abgehalten werden sollten.
description: China aktuell, China aktuell - Oktober 2004
Human Health and Climate Change: Leverage Points for Adaptation in Urban Environments
Creators: name: Proust, Katrina
name: Newell, Barry
name: Brown, Helen
name: Capon, Anthony
name: Browne, Chris
name: Burton, Anthony
name: Dixon, Jane
name: Mu, Lisa
name: Zarafu, Monica
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The design of adaptation strategies that promote urban health and well-being in the face of climate change requires an understanding of the feedback interactions that take place between the dynamical state of a city, the health of its people, and the state of the planet. Complexity, contingency and uncertainty combine to impede the growth of such systemic understandings. In this paper we suggest that the collaborative development of conceptual models can help a group to identify potential leverage points for effective adaptation. We describe a three-step procedure that leads from the development of a high-level system template, through the selection of a problem space that contains one or more of the group’s adaptive challenges, to a specific conceptual model of a sub-system of importance to the group. This procedure is illustrated by a case study of urban dwellers’ maladaptive dependence on private motor vehicles. We conclude that a system dynamics approach, revolving around the collaborative construction of a set of conceptual models, can help communities to improve their adaptive capacity, and so better meet the challenge of maintaining, and even improving, urban health in the face of climate change.
Data from: Jointly representing long-range genetic similarity and spatially heterogeneous isolation-by-distance
Creators: name: Shastry, Vivaswat
name: Musiani, Marco
name: Novembre, John
Publisher: name: Zenodo
Year: 2025
Subjects: Afro-Eurasia
migration
admixture
spatial
Canis lupus
Homo Sapiens
North America

description: Isolation-by-distance patterns in genetic variation are a widespread feature of the geographic structure of genetic variation in many species, and many methods have been developed to illuminate such patterns in genetic data. However, long-range genetic similarities also exist, often as a result of rare or episodic long-range gene flow.  Jointly characterizing patterns of isolation-by-distance and long-range genetic similarity in genetic data is an open data analysis challenge that, if resolved, could help produce more complete representations of the geographic structure of genetic data in any given species.  Here, we present a computationally tractable method that identifies long-range genetic similarities in a background of spatially heterogeneous isolation-by-distance variation. The method uses a coalescent-based framework, and models long-range genetic similarity in terms of directional events with source fractions describing the fraction of ancestry at a location tracing back to a remote source. The method produces geographic maps annotated with inferred long-range edges, as well as maps of uncertainty in the geographic location of each source of long-range gene flow.  We have implemented the method in a package called FEEMSmix (an extension to FEEMS from Marcus et al 2021), and validated its implementation using simulations representative of typical data applications.  We also apply this method to two empirical data sets. In a data set of over 4,000 humans (Homo sapiens) across Afro-Eurasia, we recover many known signals of long-distance dispersal from recent centuries. Similarly, in a data set of over 100 gray wolves (Canis lupus) across North America, we identify several previously unknown long-range connections, some of which were attributable to recording errors in sampling locations. Therefore, beyond identifying genuine long-range dispersals, our approach also serves as a useful tool for quality control in spatial genetic studies.
description: The wolf data set (wolvesadmix_corrected) consists of 108 individuals and 17,729 SNPs. For this study, we correct the locations of two individuals based on an analysis of the sample meta data and remove three individuals with ambiguous locations from the original data set of 111 wolves compiled in Schweizer et al 2016 (data available here:https://doi.org/10.5061/dryad.p8cz8wb18). 

The human data set (c1global1nfd_public) consists of 4,070 individuals and 19,954 SNPs. For this study, we subset to individuals with public sharing permissions from the larger data set of 4,697 individuals in Peter et al 2020. (data available on Zenodo as 'Supplemental information').
Handling missing data, censored values and measurement error in machine learning models using multiple imputation for early stage drug discovery
Creators: name: Swiers, Rowan
Publisher: name: Zenodo
Year: 2020

description: Multiple imputation is a technique for handling missing data, censored values and measurement error. Currently it is underused in the machine learning field due to lack of familiarity and experience with the technique, whilst other missing data solutions such as full Bayesian models can be hard to set up. However, randomization-based evaluations of Bayesianly derived repeated imputations can provide approximately valid inference of the posterior distributions and allow use of techniques which rely upon complete data such as SVMs and random Forest models. This paper, using simulated data sets inspired by AstraZeneca drug data, shows how multiple imputation techniques can improve the analysis of data with missing values or with uncertainty. We pay close attention to the prediction of Bayesian posterior coverage due its importance in industrial applications. Comparisons are made to other commonly used methods of handling missing data such as single uniform imputation and data removal. Furthermore, we review several standard multiple imputation models and compare them on our simulated data sets. We provide recommendations on when to use each technique and where extra care is needed based upon data distributions. Finally, using simulated data, we give examples of how correct use of multiple imputation can affect investment decisions in the early stages of drug discovery. Analysis was performed using both Python and Stan and is provided in a Jupyter notebook.
Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains
Creators: name: Li, Xinrui
name: Schulte, Patricia
name: Godin, David V
name: Cheng, Kimberly M
Publisher: name: BioMed Central
Year: 2016

description: Background: Two atherosclerosis-susceptible and -resistant Japanese quail (Coturnix japonica) strains obtained by divergent selection are commonly used as models to study atherosclerosis, but no genetic characterization of their phenotypic differences has been reported so far. Our objective was to examine possible differences in the expression of genes involved in cholesterol metabolism and transport in the liver between these two strains and to evaluate the value of this model to analyze the gene system affecting cholesterol metabolism and transport. Methods: A factorial study with both strains (atherosclerosis-susceptible versus atherosclerosis-resistant) and two diets (control versus cholesterol) was carried out. The mRNA concentrations of four genes involved in cholesterol biosynthesis (HMGCR, FDFT1, SQLE and DHCR7) and three genes in cholesterol transport (ABCG5, ABCG8 and APOA1) were assayed using real-time quantitative PCR. Plasma lipids were also assayed. Results: Expression of ABCG5 (control diet) and ABCG8 (regardless of dietary treatment) and expression of HMGCR, FDFT1 and SQLE (regardless of dietary treatment) were significantly higher in the atherosclerosis-resistant than in the atherosclerosis-susceptible strain. Plasma triglyceride and LDL levels, and LDL/HDL ratio were significantly higher in the atherosclerosis-susceptible than in the atherosclerosis-resistant strain fed the cholesterol diet. In the atherosclerosis-susceptible strain, ABCG5 expression regressed significantly and positively on plasma LDL level, whereas DHCR7 and SQLE expression regressed significantly and negatively on plasma triglyceride level. Conclusions: Our results provide support for the hypothesis that the atherosclerosis-resistant strain metabolizes and excretes cholesterol faster than the atherosclerosis-susceptible strain. We have also demonstrated that these quail strains are a useful model to study cholesterol metabolism and transport in relation with atherosclerosis.
Open Science: Enabling science and research data to be more interoperable and reusable
Creators: name: Stall, Shelley
name: Specht, Alison
name: Corrêa, Pedro Luiz Pizzigatti
name: David, Romain
name: Mabile, Laurence
name: Machicao, Jeaneth
name: Murayama, Yasuhiro
name: O'Brien, Margaret
name: Miyairi, Nobuko
name: Wyborn, Lesley
name: Vellenich, Danton Ferreira
name: Erdmann, Chris
Publisher: name: Forschungzentrum Jülich
Year: 2022
Subjects: Open Science
FAIR Data

description: Japan Open Science Summit 2022, JOSS 2022, Japan, 6 Jun 2022 - 10 Jun 2022; doi:10.5281/ZENODO.6626286
description: This presentation was given during the Japan Open Science Summit during Session E3: Open science, its discussions and practices in research projects.
The Pro-democracy Movement in Hong Kong and the September 2004 Legislative Council Elections
Creators: name: Cheng, Joseph Y. S.
Publisher: name: China aktuell
Year: 2020

description: The pro-democracy movement was in a difficult state in the years before the massive protest rally on July 1, 2003. There was considerable frustration with the lack of progress as no one expected any breakthrough before 2007. Even the political parties in the pro-democracy camp did not believe that democratization was an issue with much political appeal. The Democratic Party, the party with the most seats in the legislature before September 2004, and its allies could make very little impact on the government’s policy-making process. As the Tung administration enjoyed the backing of a safe majority in the legislature, it did not have to lobby for the approval of the pro-democracy groups which were treated as the Opposition. In fact, there had been little meaningful consultation between the pro-democracy groups and the government.
description: China aktuell, China aktuell - September 2004
dritten Wahlen zur Legislativversammlung der SVR Hongkong. Enttäuschung bei den Demokraten, Sieg der Demokratie
Creators: name: Willmann, Katrin
Publisher: name: China aktuell
Year: 2020

description: Am 12. September 2004 wurde die dritte Legislativversammlung (Legislative Council, kurz LegCo) der SVR Hongkong gewählt. Erstmals in der Geschichte Hongkongs konnten dabei die Hälfte der insgesamt 60 Abgeordneten direkt gewählt werden, was der demokratischen Opposition nun die theoretische Möglichkeit eines gleichwertigen Stimmenanteils eröffnete. Die Demokraten erreichten ihr Ziel eines deutlichen Zuwachses an Sitzen jedoch nicht und verharren somit weiterhin in der Position der Minderheit im Parlament, obwohl ihnen im Vorfeld, vor allem gestärkt durch die Entwicklungen der letzten Monate, sogar Chancen für das Erreichen einer Mehrheit eingeräumt worden war. Die Berichterstatter der Hongkonger und internationalen Presse beurteilten den Wahlausgang in unterschiedlicher Weise.
description: China aktuell, China aktuell - September 2004
Open Science: Enabling science and research data to be more interoperable and reusable
Creators: name: Stall, Shelley
Publisher: name: Forschungzentrum Jülich
Year: 2022
Subjects: Open Science
Open Data
FAIR Data
FAIR Software

description: Japanese Geoscience Union Meeting 2022, JpGU 2022, Chiba, Japan, 22 May 2022 - 27 May 2022; doi:10.5281/ZENODO.6575301
description: Presented at JpGU 2022, during session MGI30, Open Science with FAIR Science Data Sharing and Management and e-Infrastructures [MGI30-01] Open Science: Enabling science and research data to be more interoperable and reusable An Open Science community fosters collaboration and sharing with the goal of lowering barriers of access to publications and the scientific data and software that supports research findings. The community sets expectations on good practice that help build trust, equity, and inclusion. At AGU our Strategic Plan has set objectives to help incorporate open science practices in our own programs as well as introducing these concepts to the broader community. This talk will share this work and provide tangible ways to begin your own Open Science journey.
Zwischen Widerstand und Konformität - Zur Diversität uigurischer Identität in Xinjiang drei Jahre nach dem 11. September 2001
Creators: name: Von Hahn, Patricia
Publisher: name: China aktuell
Year: 2020

description: Im September 2002 wurde die „Ostturkestanische Islamische Bewegung“ (East Turkestan Islamic Movement, ETIM) von den Vereinten Nationen in die offizielle Liste terroristischer Gruppierungen aufgenommen. Nebulös bleiben die Motive, welche die UN schließlich zu diesem Schritt bewogen. Fest steht jedoch, dass China zuvor „Überzeugungsarbeit“ geleistet hatte, die ganz im Lichte des 11. September 2001 stand. So wurden der ETIM angeblich Verbindungen zu Osama bin Laden und dem Al-Qaida-Netzwerk, eine Vielzahl terroristischer Anschläge im zurückliegenden Jahrzehnt und eine radikal islamische Ausrichtung nachgewiesen.
description: China aktuell, China aktuell - September 2004
Persistent Identifier in Open-Access-Publikationsworkflows
Creators: name: Schirrwagen, Jochen
name: Schrader, Antonia
name: Pampel, Heinz
Publisher: name: Forschungzentrum Jülich
Year: 2022
Subjects: ORCID
ROR
ORCID DE
PIDs
Open Science
Persistent Identifier
OpenAIRE
BASE
Open Access
Publikation
Workflow

description: Open-Access-Tage 2022, OAT22, Bern, Switzerland, 19 Sep 2022 - 21 Sep 2022; doi:10.5281/ZENODO.7118359
description: In einer mittlerweile überwiegend digitalen Wissenschaftslandschaft ist die dauerhafte und verlässliche Identifizierung der mit Forschungsprozessen verknüpften Ressourcen, seiner Akteure und ihrer Publikationen mittels Persistent Identifiern (PIDs) unerlässlich geworden. Mit der wachsenden Bedeutung von PIDs im Forschungsalltag und zunehmend auch in kulturellen Kontexten, erhöhen sich aber auch die Anforderungen an das effiziente Zusammenspiel von PID-Systemen, um Nutzenden und ihre Informationssysteme bei der Anwendung von PIDs zu unterstützen. Im Vortrag werden die vielfältigen Einsatzmöglichkeiten von PIDs im Veröffentlichungsprozess von Open-Access-Publikationen näher beleuchtet. Besonderer Fokus wird dabei auf den „Digital Object Identifier“ (DOI) für die verlässliche und dauerhafte Auffindbarkeit von digitalen Forschungsobjekten, den Autor:innenidentifikator „ORCID“, die Gemeinsamen Normdatei (GND) und den Organisationsidentifikator „ROR“ gelegt. Erörtert wird welche Chancen und Herausforderungen der Einsatz von PIDs für Autor:innen und publizierende Einrichtungen im Kontext des Open-Access-Publizierens birgt. Im Konkreten wird beschrieben, an welchen Stellen im Open-Access-Publikationsworkflow wissenschaftlicher Einrichtungen, Bibliotheken und Publikationsinfrastrukturen in akademischer Trägerschaft PIDs mitgedacht und verwendet werden sollten. Hierbei wird neben den Einsatzmöglichkeiten in institutionellen Open-Access-Verlagen und -Repositorien auch die Verwendung von PIDs in Publikations- und Affiliationsrichtlinien thematisiert. Zudem wird darauf eingegangen, wie die Verbreitung von PIDs an einer Einrichtung unterstützt und Wissen zu PID-Systemen vermittelt werden kann, um das Zusammenspiel zwischen Menschen und Maschinen im Publikationsprozess zu erleichtern. Darüber hinaus werden aktuelle nationale (z. B. ORCID DE) und internationale Initiativen (z. B. Research Data Alliance, OpenAIRE) im Kontext von Open Science vorgestellt, die einen Beitrag zu einer vernetzte PID-Landschaft leisten und einen Rahmen für lokale PID-Anwendungen geben.
SVR Macau
Creators: name: Jen-Kai, Liu
Publisher: name: China aktuell
Year: 2020

description: Macaus Regierungschef Edmund Ho stattete vom 13. bis 18. September der Bundesrepublik einen offiziellen Besuch ab. Bislang hatte er Portugal, Frankreich, das EU-Hauptquartier in Brüssel, Belgien, Singapur, Japan, Südkorea und Mosambik besucht. Auf seiner Deutschlandroute standen die Städte München, Berlin, Leipzig, Wiesbaden und Frankfurt am Main. Er traf u.a. mit Bundeskanzler Schröder und Bayerns Ministerpräsidenten Stoiber zusammen.
description: China aktuell, China aktuell - September 2004
Role of glycogen synthase kinase-3 beta in the inflammatory response caused by bacterial pathogens
Creators: name: Cortés-Vieyra, Ricarda
name: Bravo-Patiño, Alejandro
name: Valdez-Alarcón, Juan J.
name: Juárez, Marcos C.
name: Finlay, B. Brett, 1959-
name: Baizabal-Aguirre, Víctor M.
Publisher: name: BioMed Central
Year: 2015

description: Background: Glycogen synthase kinase 3β (GSK3β) plays a fundamental role during the inflammatory response induced by bacteria. Depending on the pathogen and its virulence factors, the type of cell and probably the context in which the interaction between host cells and bacteria takes place, GSK3β may promote or inhibit inflammation. The goal of this review is to discuss recent findings on the role of the inhibition or activation of GSK3β and its modulation of the inflammatory signaling in monocytes/macrophages and epithelial cells at the transcriptional level, mainly through the regulation of nuclear factor-kappaB (NF-κB) activity. Also included is a brief overview on the importance of GSK3 in non-inflammatory processes during bacterial infection.
On The Road To Reproducible Research: Data Stewardship In Practice
Creators: name: Teperek, Marta
Publisher: name: Forschungzentrum Jülich
Year: 2018
Subjects: data stewardship
RDM
FAIR data
Open Science
TU Delft

description: Beilstein Open Science Symposium, ; doi:10.5281/ZENODO.1451925
description: Presentation given by Marta Teperek at the Beilstein Open Science Symposium on 9 October 2018.
SVR Hongkong
Creators: name: Schucher, Günter
Publisher: name: China aktuell
Year: 2020

description: Erstmals lud die parteistaatliche Führung in Beijing zehn Abgeordnete der am 12. September neu gewählten Legislativversammlung (Legislative Council) aus dem pro-demokratischen Parteienlager Hongkongs zu den Feierlichkeiten im Vorfeld des 55-jährigen Bestehens der VR China in Beijing ein.
description: China aktuell, China aktuell - September 2004
Queries for PGBench(A Property Graph Benchmark for Knowledge Graph)
Creators: name: Maindola, Meenakshi
name: Mutharaju, Raghava
Publisher: name: Zenodo
Year: 2020
Subjects: Property Graph, Property Graph Benchmark, Knowledge Graph, Benchmark

description: This resource provides Queries for PGBench, a property graph benchmark.
 PGBench provides an RDF to Property Graph converter. This converter has been used to convert data from three well-known benchmarks. The queries were a part of the same benchmarks, namely, Lehigh University Benchmark (LUBM), Berlin SPARQL Benchmark (BSBM), and SP^2 Benchmark.
 The queries were originally in SPARQL and have been converted to Gremlin and Cypher for evaluation of benchmark on Property Graph Stores like Neo4j, RedisGraph, and JanusGraph.
 There are 6 files, two for each benchmark as the name suggests. One of the two files for each benchmark contains Cypher queries and the other contains Gremlin queries. For more information on PGBench refer to the GitHub repository. Code Repository: https://github.com/kracr/pg-benchmark
Taking researchers along on the journey to FAIR
Creators: name: Teperek, Marta
Publisher: name: Forschungzentrum Jülich
Year: 2019
Subjects: FAIR
Open Science
TU Delft
Data Stewards
Data Champions
cultural change
FAIR Data
Open Hardware

description: Beilstein Open Science Symposium 2019, ; doi:10.5281/ZENODO.3492239
description: Presentation given by Marta Teperek at the Beilstein Open Science Symposium 2019 on 16 October 2019.