cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplemental Material, Online_Appendix_(1) - New Results About Difference Scores, Ratios, and Hierarchical Linear Model Parameters as Tools for Comparing Groups
Creators: name: Stolzenberg, Ross M.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Sociology

description: Supplemental Material, Online_Appendix_(1) for New Results About Difference Scores, Ratios, and Hierarchical Linear Model Parameters as Tools for Comparing Groups by Ross M. Stolzenberg in Sociological Methods & Research
Cisgenderism and transphobia in sexual health care and associations with testing for HIV and other sexually transmitted infections: Findings from the Australian Trans & Gender Diverse Sexual Health Survey
Creators: name: Rosenberg, Shoshana
name: Callander, D
name: Holt, M
name: Duck-Chong, L
name: Pony, M
name: Cornelisse, V
name: Baradaran, A
name: Duncan, DT
name: Cook, T
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Transgender and gender diverse people have unique risks and needs in the context of sexual health, but little is known about sexual health care for this population. In 2018, a national, online survey of sexual health and well-being was conducted with trans and gender diverse people in Australia (n = 1,613). Data from this survey were analysed to describe uptake of sexual health care and experiences of interpersonal and structural cisgenderism and transphobia. Experiences of cisgenderism and transphobia in sexual health care were assessed using a new, four-item scale of 'gender insensitivity', which produced scores ranging from 0 (highly gender sensitive) to 4 (highly gender insensitive). Logistic and linear regression analyses were conducted to determine if experiences of gender insensitivity in sexual health care were associated with uptake and frequency of HIV/STI testing in the 12 months prior to participation. Trans and gender diverse participants primarily accessed sexual health care from general practice clinics (86.8%), followed by publicly funded sexual health clinics (45.6%), community-based services (22.3%), and general hospitals (14.9%). Experiences of gender insensitivity were common overall (73.2% of participants reported ≥2 negative experiences) but most common in hospitals (M = 2.9, SD = 1.3) and least common in community- based services (M = 1.3, SD = 1.4; p<0.001). When controlling for sociodemographic factors, social networks, general access to health care, and sexual practices, higher levels of gender insensitivity in previous sexual health care encounters were associated with a lower likelihood of recent HIV/STI testing (adjusted prevalence ratio = 0.92, 95% confidence interval [CI]:091,0.96, p<0.001) and less-frequent HIV/STI testing (B = -0.07, 95%CI:-0.10,- 0.03, p = 0.007). Given the high rates of HIV and other STIs among trans and gender diverse people in Australia and overseas, eliminating cisgenderism and transphobia in sexual health care may help improve access to diagnostic testing to reduce infection rates and support the overall sexual health and well-being of these populations.
Supplemental Material, Merriman_17120154_toSage_SuppTbls - Exploratory Study of Associations Between DNA Repair and Oxidative Stress Gene Polymorphisms and Cognitive Problems Reported by Postmenopausal Women With and Without Breast Cancer
Creators: name: Merriman, John D.
name: Sereika, Susan M.
name: Conley, Yvette P.
name: Koleck, Theresa A.
name: Yehui Zhu
name: Phillips, Mary L.
name: Bertocci, Michele A.
name: Brufsky, Adam M.
name: Bender, Catherine M.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, Merriman_17120154_toSage_SuppTbls for Exploratory Study of Associations Between DNA Repair and Oxidative Stress Gene Polymorphisms and Cognitive Problems Reported by Postmenopausal Women With and Without Breast Cancer by John D. Merriman, Susan M. Sereika, Yvette P. Conley, Theresa A. Koleck, Yehui Zhu, Mary L. Phillips, Michele A. Bertocci, Adam M. Brufsky, and Catherine M. Bender in Biological Research For Nursing
Supplemental material1 - Supplemental material for Elevation of cerebrospinal fluid cytokine/chemokines involved in innate, T cell, and granulocyte inflammation in pediatric focal cerebral arteriopathy
Creators: name: Kothur, Kavitha
name: Troedson, Christopher
name: Webster, Richard
name: Bandodkar, Sushil
name: Chu, Stephanie
name: Wienholt, Louise
name: Pope, Alun
name: Mackay, Mark T
name: Dale, Russell C
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental material1 for Elevation of cerebrospinal fluid cytokine/chemokines involved in innate, T cell, and granulocyte inflammation in pediatric focal cerebral arteriopathy by Kavitha Kothur, Christopher Troedson, Richard Webster, Sushil Bandodkar, Stephanie Chu, Louise Wienholt, Alun Pope, Mark T Mackay and Russell C Dale in International Journal of Stroke
Use of Spatio-Temporal Habitat Suitability Modelling to Prioritise Areas for Common Carp Biocontrol in Australia Using the Virus CyHV-3
Creators: name: Graham, K
name: Gilligan, D
name: Brown, Paul
name: van Klinken, RD
name: McColl, KA
name: Durr, PA
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Common carp (Cyprinus carpio) are an invasive species of the rivers and waterways of south-eastern Australia, implicated in the serious decline of many native fish species. Over the past 50 years a variety of control options have been explored, all of which to date have proved either ineffective or cost prohibitive. Most recently the use of cyprinid herpesvirus 3 (CyHV-3) has been proposed as a biocontrol agent, but to assess the risks and benefits of this, as well as to develop a strategy for the release of the virus, a knowledge of the fundamental processes driving carp distribution and abundance is required. To this end, we developed a novel process-based modelling framework that integrates expert opinion with spatio-temporal datasets via the construction of a Bayesian Network. The resulting weekly networks thus enabled an estimate of the habitat suitability for carp across a range of hydrological habitats in south-eastern Australia, covering five diverse catchment areas encompassing in total a drainage area of 132,129 km2 over a period of 17–27 years. This showed that while suitability for adult and subadult carp was medium-high across most habitats throughout the period, nevertheless the majority of habitats were poorly suited for the recruitment of larvae and young-of-year (YOY). Instead, high population abundance was confirmed to depend on a small number of recruitment hotspots which occur in years of favourable inundation. Quantification of the underlying ecological drivers of carp abundance thus makes possible detailed planning by focusing on critical weaknesses in the population biology of carp. More specifically, it permits the rational planning for population reduction using the biocontrol agent, CyHV-3, targeting areas where the total population density is above a “damage threshold” of approximately 100 kg/ha.
MSJ794063_supplementary_material – Supplemental material for Over three decades study populations in progressive multiple sclerosis have become older and more disabled, but have lower on-trial progression rates: A systematic review and meta-analysis of 43 randomised placebo-controlled trials
Creators: name: Nicholas, Richard S
name: Han, Erika
name: Raffel, Joel
name: Chataway, Jeremy
name: Friede, Tim
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, MSJ794063_supplementary_material for Over three decades study populations in progressive multiple sclerosis have become older and more disabled, but have lower on-trial progression rates: A systematic review and meta-analysis of 43 randomised placebo-controlled trials by Richard S Nicholas, Erika Han, Joel Raffel, Jeremy Chataway and Tim Friede in Multiple Sclerosis Journal
Assessing Effects of Covid-19 Responses on Mental Health in Malawi (Poster)
Creators: name: Ndasauka, Yamikani
name: Mchenga, Martina
name: Kondowe, Fiskani
name: M'manga, Chilungamo
name: Kainja, Jimmy
name: Maliwichi, Limbika
name: Nyamali, Simunye
Publisher: name: My University
Year: 2023

description: The Coronavirus Disease (Covid-19) pandemic has overwhelmed health systems in all countries, especially those in the least developing countries, Malawi included. As such, this project sought to investigate the effects of Covid-19 responses on mental health in Malawi in terms of perception toward mental health in general, the mental health of adolescents and health workers and mental health services. The project had three main phases, research, awareness campaign and dissemination.
N-acetylcysteine (NAC) for methamphetamine dependence: A randomised controlled trial
Creators: name: McKetin, R
name: Dean, OM
name: Turner, A
name: Kelly, PJ
name: Quinn, B
name: Lubman, DI
name: Dietze, Paul
name: Carter, G
name: Higgs, Peter
name: Sinclair, B
name: Reid, D
name: Baker, AL
name: Manning, V
name: Pas, NT
name: Thomas, T
name: Bathish, R
name: Raftery, DK
name: Wrobel, A
name: Saunders, L
name: Arunogiri, S
name: Cordaro, F
name: Hill, H
name: Hall, S
name: Clare, PJ
name: Mohebbi, M
name: Berk, M
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Methamphetamine dependence is a significant global health concern for which there are no approved medications. The cysteine prodrug, N-acetylcysteine (NAC), has been found to ameliorate glutamate dysregulation in addiction, and to reduce craving for methamphetamine and other drugs. We evaluated the efficacy and safety of NAC as a pharmacotherapy for methamphetamine dependence. Methods: A parallel double-blind randomised placebo-controlled trial of people dependent on methamphetamine recruited from Geelong, Melbourne and Wollongong, Australia, between July 2018 and December 2019. Participants were randomised to receive either 12 weeks of oral NAC (2400 mg/day) or matched placebo, delivered as a take-home medication. The primary outcome was methamphetamine use, measured in two ways: (a) change in days of use in the past 4 weeks from baseline to weeks 4, 8 and 12, assessed using the Timeline Followback; and (b) methamphetamine-positive oral fluid samples taken weekly. Analyses were intention-to-treat and based on imputed data. Secondary outcomes were craving, severity of dependence, withdrawal severity and psychiatric symptoms (depression, suicidality, hostility and psychotic symptoms). Significance levels were p < 0.025 for primary outcomes and p < 0.01 for secondary outcomes. Adverse events were compared between groups by system organ class. The study was prospectively registered, ACTRN12618000366257. Results: Participants (N = 153; 59% male, mean [SD] age 38 [8]) were randomised to placebo (n = 77) or NAC (n = 76). Both groups had a median (IQR) of 24 (15–28) days of methamphetamine use in the 4 weeks prior to baseline. Both groups significantly reduced methamphetamine use (mean [SE] reduction of 7.3 [1.2]) days for placebo, 6.8 [1.2] for NAC) but NAC did not reduce days of methamphetamine use more than placebo (group difference of 0.5 days, 97.5% CI -3.4–4.3). There was no significant effect of NAC on methamphetamine-positive oral fluid samples (placebo 79%, NAC 76%; mean difference -2.6, 97.5% CI -12.6–7.4). NAC did not significantly reduce craving, severity of dependence, withdrawal, suicidality, depression, hostility or psychotic symptoms relative to placebo. Adverse events did not differ significantly between placebo and NAC groups. Interpretation: These findings suggest that take-home oral NAC has no significant effect on methamphetamine use or most clinically related outcomes amongst people who are dependent on the drug.
The hydroperoxyl radical scavenging activity of sulfuretin: Insights from theory
Creators: name: Hoa, NT
name: Hang, DTN
name: Hieu, DP
name: Van Truong, H
name: Hoang, LP
name: Mechler, Adam
name: Vo, Quan Van
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Sulfuretin (SFR), which is isolated from Rhus verniciflua, Toxicodendron vernicifluum, Dahlia, Bidens tripartite and Dipterx lacunifera, is one of the most important natural flavonoids. This compound is known to have numerous biological activities; among these, the antioxidant activity has not been thoroughly studied yet. In this study, the hydroperoxyl scavenging activity of SFR was examined by using density functional theory calculations. SFR is predicted to be an excellent HOO • scavenger in water at pH = 7.40 with k overall = 4.75 × 10 7 M -1 s -1, principally due to an increase in the activity of the anionic form following the single-electron transfer mechanism. Consistently, the activity of the neutral form is more prominent in the non-polar environment with k overall = 1.79 × 10 4 M -1 s -1 following the formal hydrogen transfer mechanism. Thus, it is predicted that SFR exhibits better HOO • antiradical activity than typical antioxidants such as resveratrol, ascorbic acid or Trolox in the lipid medium. The hydroperoxyl radical scavenging of SFR in the aqueous solution is approximately 530 times faster than that of Trolox and similar to ascorbic acid or resveratrol. This suggests that SFR is a promising radical scavenger in physiological environments.
Additional file 1 of Evaluating the potential of whole-genome sequencing for tracing transmission routes in experimental infections and natural outbreaks of bovine respiratory syncytial virus
Creators: name: Johnson, Paul C. D.
name: Hägglund, Sara
name: Näslund, Katarina
name: Meyer, Gilles
name: Taylor, Geraldine
name: Orton, Richard J.
name: Zohari, Siamak
name: Haydon, Daniel T.
name: Valarcher, Jean François
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Tables and figures giving additional detail on the design and outcomes of experiment G, NCBI accession numbers, and additional details of analyses of coverage, reliability, error threshold selection, bottleneck size estimation, and probabilistic transmission route inference.
Additional file 2 of Evaluating the potential of whole-genome sequencing for tracing transmission routes in experimental infections and natural outbreaks of bovine respiratory syncytial virus
Creators: name: Johnson, Paul C. D.
name: Hägglund, Sara
name: Näslund, Katarina
name: Meyer, Gilles
name: Taylor, Geraldine
name: Orton, Richard J.
name: Zohari, Siamak
name: Haydon, Daniel T.
name: Valarcher, Jean François
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2. The genomic distribution of depth of coverage is plotted for 47 whole viral genome sequences from experiments A, B, C, D, F and G (n = 40), and from the field outbreak samples (n = 7).
Climate change impacts on inflows into lake eppalock reservoir from upper campaspe catchment
Creators: name: Yilmaz, Abdullah
name: Atabay, S
name: Assar, KH Amou
name: Imteaz, MA
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Climate change has significant effects on societies and ecosystems. Due to the strong link between climate and the hydrological cycle, water resources is one of the most affected fields by climate change. It is of great importance to investigate climate change effects on streamflows by producing future streamflow projections under different scenarios to create adaptation measures and mitigate potential impacts of climate change. The Upper Campaspe Catchment (UCC), located at North Central Victoria in Australia, is a significant catchment as it provides a large portion of total inflow to the Lake Eppalock Reservoir, which supplies irrigation to the Campaspe Irrigation district and urban water to Bendigo, Heathcote, and Ballarat cities. In this study, climate change effects on monthly streamflows in the UCC was investigated using high resolution future climate data from CSIRO and MIROC climate models in calibrated IHACRES hydrological model. The IHACRES model was found to be very successful to simulate monthly streamflow in UCC. Remark-able streamflow reductions were projected based on the climate input from both models (CSIRO and MIROC). According to the most optimistic scenario (with the highest projected streamflows) by the MIROC-RCP4.5 model in near future (2035–2064), the Upper Campaspe River will com-pletely dry out from January to May. The worst scenario (with the lowest streamflow projection) by the CSIRO-RCP8.5 model in the far future (2075–2104) showed that streamflows will be produced only for three months (July, August, and September) throughout the year. Findings from this study indicated that climate change will have significant adverse impacts on reservoir inflow, operation, water supply, and allocation in the study area.
MPEC 2024-P149 : 2024 PX3
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 PX3

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
The modern hospital executive, micro improvements, and the rise of antimicrobial resistance
Creators: name: Broom, A
name: Kenny, K
name: Kirby, E
name: Davis, M
name: Dodds, Susan
name: Post, J
name: Broom, J
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 38
subject: Economics
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems
classificationCode: 44
subject: Human society

description: No description supplied
Non-Bloch-Siegert-type power-induced shift of two-photon spin resonances in organic light-emitting diodes
Creators: name: Alwood, SI
name: Hosseinzadeh, S
name: Mkhitaryan, Vagharsh V.
name: Tennahewa, TH
name: Malissa, H.
name: Jiang, W
name: Burn, P. L.
name: Boehme, Christoph
name: Darwish, T. A.
name: Lupton, John M.
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: 530 Physik

description: We present Floquet theory based predictions and electrically detected magnetic resonance (EDMR) experiments to elucidate the nature of multiphoton magnetic resonance shifts of charge-carrier spin states in films of the perdeuterated π-conjugated polymer poly[2-(2-ethylhexyloxy-d17)-5-methoxy-d3-1,4-phenylenevinylene-d4] (d-MEH-PPV) under strong magnetic resonant drive conditions (radiation amplitude B1 comparable to Zeeman field B0). Room-temperature, continuous-wave EDMR experiments on d-MEH-PPV-based, electroluminescent, bipolar-injection diodes [i.e., organic light-emitting diodes (OLEDs)] confirm the ability of a nonperturbative numerical method to make quantitative predictions of two-photon resonance shifts in such devices. Additional numerical simulations show that the two-photon resonance shift with increasing power is nearly the same under both linearly and circularly polarized drive, in contrast to the one-photon shift, which only occurs under conditions of noncircularly polarized drive. We therefore treat the Floquet Hamiltonian analytically using arbitrary amplitudes of the co- and counterrotating components of the radiation field to gain insight into the nature of the polarization dependence of multiphoton resonance shifts. The results show that multiphoton resonance shifts depend on both the co- and counterrotating components of an arbitrarily polarized drive field, whereas the one-photon shift depends only on the counterrotating component.
Matrix Metalloproteinase-3 (MMP-3) Polymorphisms are Associated with Prolonged ECG-Derived QTc Interval: A Cross-Sectional Study of the Australian Rural Population
Creators: name: Lu, Y
name: Ussher, N
name: Zhou, Y
name: Jelinek, H
name: Hambly, B
name: Li, Amy
name: McLachlan, CS
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Matrix metalloproteinases (MMPs) are enzymes that are integral in extracellular matrix (ECM) remodeling. In age or disease, ECM may become dysregulated and contribute to fibrosis, which impairs cardiac electrical conduction. Two alleles regulate matrix metalloproteinase-3 (MMP-3) activity: one with five adenosine bases (5A; associated with higher MMP-3 activity and decreased fibrosis) and another with six adenosine bases (6A; associated with lower MMP-3 activity and increased fibrosis). Here, we determined whether ECG-derived QTc and related parameters are associated with the MMP-3 5A/6A genotype in a cross-section of the Australian rural population. A retrospective cross-sectional population was obtained from the Charles Sturt University Diabetes Screening Research Initiative. Genotype and resting 12-lead ECG parameters of 295 participants were analyzed. Amongst these participants, 85 individuals carried the 5A/5A genotype, 141 individuals carried the 5A/6A genotype, and 65 individuals carried the 6A/6A genotype. Compared to 5A/5A genotype carriers, 5A/6A genotype carriers had a significantly longer QTc duration by 9.50 ms (95% CI: 3.48-15.52, p = 0.002), whilst 6A/6A genotype carriers had an even longer QTc duration by 12.19 ms (95% CI: 5.04-19.34, p = 0.001). We found an association between MMP-3 5A/6A polymorphisms and QTc, independent of adjustments for age, gender, alcohol consumption, smoking status, body mass index and blood pressure.
Supplemental material for Cost-effectiveness analysis of erenumab for the preventive treatment of episodic and chronic migraine: Results from the US societal and payer perspectives
Creators: name: Sussman, Matthew
name: Benner, Jennifer
name: Neumann, Peter
name: Menzin, Joseph
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material for Cost-effectiveness analysis of erenumab for the preventive treatment of episodic and chronic migraine: Results from the US societal and payer perspectives by Matthew Sussman, Jennifer Benner, Peter Neumann and Joseph Menzin in Cephalalgia
Attitudes to and experiences of intimate partner violence among Rohingya women who married before eighteen years of age
Creators: name: Islam, Md
name: Khan, MN
name: Rahman, MM
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Currently, around a million Rohingya refugees live in Cox’s Bazar, Bangladesh. This study examines the attitudes toward physical abuse and experiences of intimate partner violence (IPV) of Rohingya refugee women who experienced child marriage. A cross-sectional survey was conducted in the Rohingya refugee settlement at Cox’s Bazar, Bangladesh. Attitudes towards physical abuse have been assessed by a set of five questions that asked the situation under which ‘hitting or beating’ one’s wife is justifiable. Multivariable logistic regressions are used to examine the associations of exposure to child marriage with (i) attitudes towards the justification of physical abuse by one’s husband and (ii) experiences of IPV in the 12 months prior to the survey. Data are available for 486 participants. Overall, 61.32% of women experienced child marriage (married before 18 years of age) and they were more likely to have strongly justified beatings/hitting one’s wife under certain circumstances (Adjusted Odds Ratio (AOR) = 2.71; 95%CI: 1.78, 4.11), and to have experienced such IPV by their husbands in the 12 months prior to the survey (AOR = 1.72; 95%CI: 1.13, 2.61). These AORs are higher for women married at ages 12–14 than those married at 15–17. Having some formal education among husband and wife is protective of abuse within a marriage. Rohingya women’s attitudes towards and experiences of IPV are associated with their exposure to child marriage. Interventions for stopping child marriage, marriage registration, social support group, and legal interventions are needed. Offering formal education to all children needs to be prioritized.
Supplemental_Material_For_Identification_of_G-quadruplex_Inhibitors_of_MYC_Expression_Through_Affinity_Selection_Mass_Spectrometry_by_Flusberg_et_al – Supplemental material for Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection–Mass Spectrometry
Creators: name: Flusberg, Deborah A.
name: Rizvi, Noreen F.
name: Kutilek, Victoria
name: Andrews, Christine
name: Saradjian, Peter
name: Chamberlin, Chad
name: Curran, Patrick
name: Swalm, Brooke
name: Kattar, Sam
name: Smith, Graham F.
name: Dandliker, Peter
name: Nickbarg, Elliott B.
name: O’Neil, Jennifer
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental_Material_For_Identification_of_G-quadruplex_Inhibitors_of_MYC_Expression_Through_Affinity_Selection_Mass_Spectrometry_by_Flusberg_et_al for Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection–Mass Spectrometry by Deborah A. Flusberg, Noreen F. Rizvi, Victoria Kutilek, Christine Andrews, Peter Saradjian, Chad Chamberlin, Patrick Curran, Brooke Swalm, Sam Kattar, Graham F. Smith, Peter Dandliker, Elliott B. Nickbarg and Jennifer O’Neil in SLAS Discovery
Additional file 1 of Validation and reliability of the Dutch version of the EORTC QLQ-BLM30 module for assessing the health-related quality of life of patients with muscle invasive bladder cancer
Creators: name: Ripping, T. M.
name: Rammant, E.
name: Witjes, J. A.
name: Aaronson, N. K.
name: van Hemelrijck, M.
name: van Hoogstraten, L. M. C.
name: Kiemeney, L. A.
name: Aben, K. K. H.
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1.
The dog–owner relationship: Refinement and validation of the italian c/dors for dog owners and correlation with the laps
Creators: name: Riggio, G
name: Piotti, P
name: Diverio, S
name: Borrelli, C
name: Di Iacovo, F
name: Gazzano, A
name: Howell, Tiffani
name: Pirrone, F
name: Mariti, C
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The Cat/Dog–Owner Relationship Scale (C/DORS) can be administered to both dog and cat owners. However, the scale as a whole has never been validated on a sample of dog owners. Furthermore, it has never been translated into Italian. The aim of this study was to translate the C/DORS into Italian, modify its response scale in order to improve the degree of response variability, and test its validity and reliability on a sample of dog-owners. Exploratory factor analysis revealed the same three-factor structure (Perceived Emotional Closeness = PEC, Pet–Owner Interactions = POI, Perceived Costs = PC) as the original English version, although some items had to be removed because of low-or cross-loadings. The validity of the construct was confirmed by confirmatory factor analysis, by the correlations between each of the subscales and the C/DORS total score, and by the correlations with the Lexington Attachment to Pets Scale. Cronbach’s α values for each subscale were above acceptable levels. Student owners scored higher on PEC and POI than owners with other occupations. Owners of dogs with behavioural problems scored lower on PEC and higher on PC. Keeping the dog outdoor was associated with lower POI. Finally, pet dog owners scored higher on PEC than AAI dog owners.
Additional file 2 of Validation and reliability of the Dutch version of the EORTC QLQ-BLM30 module for assessing the health-related quality of life of patients with muscle invasive bladder cancer
Creators: name: Ripping, T. M.
name: Rammant, E.
name: Witjes, J. A.
name: Aaronson, N. K.
name: van Hemelrijck, M.
name: van Hoogstraten, L. M. C.
name: Kiemeney, L. A.
name: Aben, K. K. H.
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 2.
An Integrative Analysis of the Micro-RNAs Contributing in Stemness, Metastasis and B-Raf Pathways in Malignant Melanoma and Melanoma Stem Cell
Creators: name: Sahranavardfard, P
name: Madjd, Z
name: Razavi, AE
name: Ghanadan, A
name: Firouzi, J
name: Khosravani, P
name: Ghavami, S
name: Ebrahimie, Esmaeil
name: Ebrahimi, M
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Objective: Epithelial-mesenchymal transition (EMT) and the stemness potency in association with BRAF mutation are in dispensable to the progression of melanoma. Recently, microRNAs (miRNAs) have been introduced as the regulator of a multitude of oncogenic functions in most of tumors. Therefore identifying and interpreting the expression patterns of these miRNAs is essential. The present study sought to find common miRNAs regulating all three important pathways in melanoma development. Materials and Methods: In this experimental study, 18 miRNAs that importantly contribute to EMT and have a role in regulating self-renewal and the BRAF pathway were selected based on current literature and cross-analysis with available databases. Subsequently, their expression patterns were evaluated in 20 melanoma patients, normal tissues, serum from patients and control subjects, and melanospheres. Pattern discovery and integrative regulatory network analysis were used to find the most important miRNAs in melanoma progression. Results: Among 18 selected miRNAs, miR-205, -141, -203, -15b, and -9 were differentially expressed in tumor samples than normal tissues. Among them, miR-205, -15b, and -9 significantly expressed in serum samples and healthy donors. Attribute Weighting and decision trees (DT) analysis presented evidence that the combination of miR-205, -203, -9, and -15b can regulate self-renewal and EMT process, by affecting CDH1, CCND1, and VEGF expression. Conclusion: We suggested here that miR-205, -15b, -203, -9 pattern as the key miRNAs linked to melanoma status, the pluripotency, proliferation, and motility of malignant cells. However, further investigations are required to find the mechanisms underlying the combinatory effects of the above mentioned miRNAs.
Supplementary_Data - The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils
Creators: name: Josephson, Lee
name: Stratman, Nancy
name: Liu, YuTing
name: Qian, Fang
name: Liang, Steven H.
name: Vasdev, Neil
name: Shil Patel
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Medicine
subject: Cell Biology
subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplementary_Data for The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils by Lee Josephson, Nancy Stratman, YuTing Liu, Fang Qian, Steven H. Liang, Neil Vasdev, and Shil Patel in Molecular Imaging
Field-deployable recombinase polymerase amplification assay for specific, sensitive and rapid detection of the us select agent and toxigenic bacterium, rathayibacter toxicus
Creators: name: Arif, M
name: Busot, GY
name: Mann, R
name: Rodoni, Brendan
name: Stack, JP
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Rathayibacter toxicus is a toxigenic bacterial pathogen of several grass species and is responsible for massive livestock deaths in Australia and South Africa. Due to concern for animal health and livestock industries, it was designated a U.S. Select Agent. A rapid, accurate, and sensitive in-field detection method was designed to assist biosecurity surveillance surveys and to support export certification of annual ryegrass hay and seed. Complete genomes from all known R. toxicus populations were explored, unique diagnostic sequences identified, and target-specific primers and a probe for recombinase polymerase amplification (RPA) and endpoint PCR were designed. The RPA reaction ran at 37 °C and a lateral flow device (LFD) was used to visualize the amplified products. To enhance reliability and accuracy, primers and probes were also designed to detect portions of host ITS regions. RPA assay specificity and sensitivity were compared to endpoint PCR using appropriate inclusivity and exclusivity panels. The RPA assay sensitivity (10 fg) was 10 times more sensitive than endpoint PCR with and without a host DNA background. In comparative tests, the RPA assay was unaffected by plant-derived amplification inhibitors, unlike the LAMP and end-point PCR assays. In-field validation of the RPA assay at multiple sites in South Australia confirmed the efficiency, specificity, and applicability of the RPA assay. The RPA assay will support disease management and evidence-based in-field biosecurity decisions.
Inflammation and Cell Death of the Innate and Adaptive Immune System during Sepsis
Creators: name: Nedev, Christina
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Sepsis is a life-threatening medical condition that occurs when the host has an uncontrolled or abnormal immune response to overwhelming infection. It is now widely accepted that sepsis occurs in two concurrent phases, which consist of an initial immune activation phase followed by a chronic immunosuppressive phase, leading to immune cell death. Depending on the severity of the disease and the pathogen involved, the hosts immune system may not fully recover, leading to ongoing complications proceeding the initial infection. As such, sepsis remains one of the leading causes of morbidity and mortality world-wide, with treatment options limited to general treatment in intensive care units (ICU). Lack of specific treatments available for sepsis is mostly due to our limited knowledge of the immuno-physiology associated with the disease. This review will provide a comprehensive overview of the mechanisms and cell types involved in eliciting infection-induced immune activation from both the innate and adaptive immune system during sepsis. In addition, the mechanisms leading to immune cell death following hyperactivation of immune cells will be explored. The evaluation and better understanding of the cellular and systemic responses leading to disease onset could eventuate into the development of much needed therapies to combat this unrelenting disease.
Spread of anthelmintic resistance in intestinal helminths of dogs and cats is currently less pronounced than in ruminants and horses – Yet it is of major concern
Creators: name: von Samson-Himmelstjerna, G
name: Thompson, RA
name: Krücken, J
name: Grant, Warwick
name: Bowman, DD
name: Schnyder, M
name: Deplazes, P
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Anthelmintic resistance (AR) has thus far only rarely been reported for intestinal helminths of dogs and cats, in contrast to parasites of livestock and horses. We highlight possible reasons for this striking and important discrepancy, including ecological, biological and genetic factors and/or intervention regimens of key intestinal helminths concerning both host groups. In view of the current knowledge related to the genetics, mechanisms and principles of AR development, we point at issues which in our view contribute to a comparatively lower risk of AR development in intestinal helminths of dogs and cats. Finally, we specify research needs and provide recommendations by which, based on the available information about AR in ruminant and equine helminths, the development of AR in dog and cat helminths may best be documented, prevented or at least postponed.
Neural Representations of Death in the Cortical Midline Structures Promote Temporal Discounting
Creators: name: Yanagisawa, Kuniaki
name: Kashima, Emiko
name: Shigemune, Yayoi
name: Nakai, Ryusuke
name: Abe, Nobuhito
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Abstract Death is an important reminder that our lives are finite. Although some studies have shown that thinking about one’s own death increases temporal discounting (i.e., the devaluing of future rewards), the underlying neural mechanisms are still unknown. In a functional magnetic resonance imaging experiment, we compared the neural and behavioral processes of temporal discounting across four conditions involving distinct types of future thinking (death related, negative, neutral, and positive). Replicating prior research, the behavioral evidence showed that temporal discounting increased when thinking about one’s own future death. Multivoxel pattern analysis showed that death-related future thinking was decoded in default mode regions, including the inferior parietal lobule, precuneus, and medial prefrontal cortex (MPFC). When future thinking was death related (vs. negative), increased temporal discounting was associated with a higher decoding accuracy in the precuneus and MPFC. The present findings suggest that death-related neural representations are distributed across default mode regions, and neural populations in the cortical midline structures play a crucial role in the integration of one's own death into economic decision-making.
Supplemental_Material.pdf.docx – Supplemental material for The roller coaster ride: Our music teacher educator identity development
Creators: name: Kastner, Julie Derges
name: Reese, Jill
name: Pellegrino, Kristen
name: Russell, Heather A.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Supplemental_Material.pdf.docx for The roller coaster ride: Our music teacher educator identity development by Julie Derges Kastner, Jill Reese, Kristen Pellegrino and Heather A. Russell in Research Studies in Music Education
PHP799771_Supplemental_Appendix_D – Supplemental material for Development, Implementation, and Evaluation of a Course on Chronic Disease to Enhance Critical Thinking in Health Promotion Undergraduate Students
Creators: name: Aubrianne E. Rote
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, PHP799771_Supplemental_Appendix_D for Development, Implementation, and Evaluation of a Course on Chronic Disease to Enhance Critical Thinking in Health Promotion Undergraduate Students by Aubrianne E. Rote in Pedagogy in Health Promotion
Obesity bias and stigma, attitudes and beliefs among entry-level physiotherapy students in the Republic of Ireland: a cross sectional study
Creators: name: O'Donoghue, G
name: McMahon, S
name: Holt, A
name: Nedai, M
name: Nybo, T
name: Peiris, Casey
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Objective: To explore entry-level physiotherapy students’ attitudes and beliefs relating to weight bias and stigmatisation in healthcare. Design: Cross sectional survey of physiotherapy students. Methods: All final year physiotherapy students (n = 215) enrolled in entry-level physiotherapy programmes in the Republic of Ireland were invited to participate. Each received a questionnaire, consisting of 72 questions, within four key sections. Descriptive statistics and frequencies were used to analyse the data. Results: A response rate of 83% (179/215) was achieved. Whilst physiotherapy students, overall, had a positive attitude towards people with obesity, 29% had a negative attitude towards people with obesity, 24% had a negative attitude towards managing this population and most (74%) believed obesity was caused by behavioural and individual factors. Over one third of students (35%) reported that they would not be confident in managing patients with obesity and more than half (54%) felt treating patients with obesity was not worthwhile. Conclusion: This study provides preliminary findings to suggest that weight stigma-reduction efforts are warranted for physiotherapy students. Helping students to understand that obesity is a complex, chronic condition with multiple aspects requiring a multi-faceted approach to its management might be the first step towards dispelling these negative attitudes towards patients living with obesity. Inclusion of a formal obesity curriculum should perhaps now be part of the contemporary physiotherapy students’ education.
Local wisdom and archipelago agriculture: Poverty in Maluku
Creators: name: Pattinama, MJ
name: Nanere, Marthin
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Maluku is an archipelago province where its inhabitants mostly settle on small islands and conduct agricultural activities on very limited land with relatively low fertility rates. In such conditions, islanders' local wisdom in Maluku is one of the cultural values that are still manifested in their life order, which is the social capital of archipelago communities. Local wisdom is derived from society's knowledge and has a high social value in sustaining their lives when faced with all limitations and challenges. Islanders often face difficulties in marketing their agricultural products and limited transportation access to get a good education and health services. This has contributed to poverty among people living on small islands, as indicated by a poverty rate of 18.5%. Interestingly, local wisdom has been practised by communities for a long time when undertaking their agricultural activities. It is anticipated that global climate change also impacts agricultural practices undertaken by the islanders in Maluku. Therefore, this article's objectives were to (1) analyze the form of local wisdom of islanders and its impact on sustainable archipelago agriculture development, (2) suggest ways to alleviate poverty in Maluku using local wisdom as social capital. The finding suggests that local wisdom's value cannot be separated from the interactions between humans and their environment. This is a driving factor in the advancement of economic and socio-cultural aspects. Responsible marketing is another aspect that should be taken into account.
Supplementary Material - TFG JLG
Creators: name: López Galán, Jaime
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310403
subject: Biological adaptation
classificationCode: 310405
subject: Evolutionary ecology
classificationCode: 310410
subject: Phylogeny and comparative analysis

description: A very frequent pattern in vertebrate fauna is to acquire the biggest body sizes when a filter-feeding ecology is present among marine species. This has led to an enduring trophic guild of large-bodied filter-feeding vertebrates which has been present in Earth’s history for a long time. In this study, we provide evidence on the evolution of these extant planktivorous sharks from ancestrally big-bodied predators. Besides, a phylomorphospace approach based on eight biologically-relevant variables related to filter-feeding allows to see a shared region in the multidimensional trait space, suggesting the convergence of microphagous vertebrates to a common adaptive peak. The lack of well-preserved fossils of transitional shark forms does not permit to assess if the morphological changes involved in the specialization to microphagy took place in the same sequence as in other large-bodied filter-feeding vertebrates.
Twelve-month findings of the MOVE Frankston randomised controlled trial of interventions to increase recreation facility usage and physical activity among adults
Creators: name: Smith, BJ
name: Mackenzie-Stewart, Ruth
name: Newton, FJ
name: Manera, Karine
name: Haregu, Tilahun
name: Bauman, A
name: Donovan, RJ
name: Mahal, A
name: Ewing, MT
name: Newton, JD
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4206
subject: Public health

description: Substantial cross-sectional evidence and limited longitudinal research indicates that the availability of recreational facilities (e.g., parks, fitness centres) is associated with physical activity participation. However, few intervention trials have investigated how recreational infrastructure can be used to reduce inactivity levels in communities. The MOVE Frankston study aimed to assess the impact of low intensity strategies to promote use of a multi-purpose leisure and aquatic centre in a socioeconomically diverse, metropolitan community. This randomised controlled trial of two years’ duration compared public awareness raising (control condition) with two interventions: mailed information about the centre and a free entry pass (I-O); and this minimal intervention supplemented by customer relations management support through telephone contact, mailed promotional materials and additional incentives (I+S). Participants (n = 1320) were inactive adults living in the City of Frankston, Melbourne Australia. There were 928 people (70.3%) followed up at 12 months (61.2% female, 52% ≥55 yrs). Compared with controls, attendance at the Centre once or more was higher in both the I-O (OR 1.79, 95% CI 1.28–2.50) and I+S groups (OR 1.46, 95% CI 1.03–2.07). The proportion of people using the centre weekly did not differ by group. The odds of being in contemplation or preparation to use the Centre were higher in both the I-O (OR 1.76, 95% CI 1.28–2.42) and I+S groups (OR 1.48, 95% CI 1.07–2.06). Total physical activity and related social and cognitive factors did not differ between the groups. The findings show that the low intensity promotional strategies prompted occasional attendance and increased readiness to use this recreational facility, a level of behaviour change unlikely to reduce non-communicable disease risk. It is recommended that more frequent customer relations contact, and involvement of healthcare providers, be tested as strategies to encourage inactive adults to take up physical activity opportunities at recreational facilities of this type.
Reaction of RD10 and Sanpatong1 Rice Varieties to the Rice Gall Midge Infestation and Their Yields
Creators: name: Natchanapong Vongburi
Publisher: name: Department of Agriculture
Year: 2002
Subjects: gall midge
yield
rice varieties
RD 10
Sanpatong 1
planting dates

description: Thai Agricultural Research Journal, 20, 1, 56-66