cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Behavioral manifestations of sexual conflict: Facultative asexuality, mating phenology, and the loss of nuptial gifts drive reproductive strategies in sclerosomatid Opiliones
Creators: name: Brown, Tyler A
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Animal Behavior
Arachnid
Facultative Parthenogenesis
Nuptial Gifts
Sexual Conflict
Sexual Selection

description: Sexual conflict is a primary driving force behind how mating behavior evolves. Despite much research on sexual conflict, however, the behavioral manifestations of sexual conflict driven by facultative asexuality, nuptial gifts, and mating phenology are not fully resolved. Leiobunine Opiliones feature all these factors: some species possess nuptial gifts and lack female genital barriers, some species lack precopulatory nuptial gifts and have female genital barriers, and some species are facultatively asexual. Temperate species also have a highly variable reproductive window, with the window of maturation varying greatly both between and within species. All these factors can greatly influence the reproduction of a species and provide mechanisms through which sexual conflict and selection might operate. In this dissertation, I investigated the reproductive behavior of Leiobunum Opiliones to determine how facultative asexuality, nuptial gifts, and mating phenology generate sexual conflict. I first used facultatively asexual Japanese Opiliones to determine whether sex ratio influenced reproductive mode. Female harvesters nearly always reproduced asexually in localities in which males were rare. Surprisingly, however, females in localities with common males also typically reproduced asexually, indicating sexual reproduction with males is likely costly. Following this, I compared sexual conflict behavior between North American sacculate species, in which males give nutritious nuptial gifts, and nonsacculate species, in which males do not. Using machine learning-based tracking, I found significantly higher levels of sexual conflict in nonsacculate species, matching predictions that nuptial gifts were lost in favor of antagonistic male behavior. Interestingly, I detected multiple suites of antagonistic strategies; L. euserratipalpe males favored extended guarding, while L. vittatum males favored extended clasping. In the final study I sought to determine how mating phenology and mating history influenced sexual conflict. I compared behavioral sexual conflict metrics between mated and unmated females and across three consecutive mate encounters. Contrary to theoretical predictions, sexual conflict did not vary with mating history or with encounter number. Throughout my dissertation, I have detected evidence of sexual conflict varying with reproductive mode and nuptial gifts presence and I have established Leiobunum harvesters as excellent species in which to study behavioral sexual conflict.
Visualising coin hoards: The Coin Hoards of the Roman Empire project (CHRE)
Creators: name: Spoerri Butcher, Marguerite
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Archaeology
subject: Numismatics/methods
subject: Numismatics

description: The Coin Hoards of the Roman Empire project (https://chre.ashmus.ox.ac.uk) provides a digital research infrastructure covering hoards of all coins in use within the Roman empire, from 30 BC to AD 518. In order to better analyse its ever growing database, containing over 5,800,000 coins for more than 14,800 validated hoards (June 2023), a range of visualisation tools has been developed. These are presented here.
Alexander_Online_Supplement_1_on_Financial_Crisis_final – Supplemental material for The Societalization of Social Problems: Church Pedophilia, Phone Hacking, and the Financial Crisis
Creators: name: Alexander, Jeffrey C.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, Alexander_Online_Supplement_1_on_Financial_Crisis_final for The Societalization of Social Problems: Church Pedophilia, Phone Hacking, and the Financial Crisis by Jeffrey C. Alexander in American Sociological Review
Investigation of the role of the PHD domain of Set4 in stress-mediated chromatin regulation in Saccharomyces cerevisiae
Creators: name: Negesse, Maraki
Publisher: name: Maryland Shared Open Access Repository
Year: 2024

description: Chromatin regulation is a dynamic process and an essential aspect of cell growth and survival. It further allows cells to adapt to changing environmental conditions, by regulating the expression of genes essential for survival during stress. One essential class of chromatin regulators are methyltransferases, a class of enzymes that methylate histones to promote differential gene expression. The yeast chromatin regulator Set4 is a member of the Set3 subfamily of SET-domain containing methyltransferases that appear to have inactive catalytic domains. This family consists of Set3 and Set4 in S. cerevisiae and homologues UpSET in Drosophila, SET-9 and SET-26 in C. elegans, and MLL5 and SETD5 in mammals. In addition to the conserved SET domains, the majority of these factors include PHD fingers that bind to H3K4 methylation and facilitate their recruitment to chromatin. In yeast, Set3 recruits histone deacetylases Hos2 and Hst1 and functions primarily as a repressor of gene expression. Despite a high sequence similarity, Set4 seems to have distinct functions in the cell. Set4 promotes cell survival in stress conditions such as oxidative stress and hypoxia. It wasshown to localize to the promoter regions of stress response genes and work with histone deacetylases in regulating their expression. Interestingly, the Set4 PHD finger is not known to bind histones in standard assays and the mechanism by which it is recruited to chromatin is unknown. The goal of this dissertation was to characterize the PHD domain of Set4 and its contribution to the regulation of stress response genes by Set4. We have shown here that the PHD domain of Set4 is important for its localization at chromatin and for its function in gene regulation. We also show that Set4 PHD binds to DNA in vitro and identify residues that mediate this interaction. Lastly, we provide evidence that Set4 chromatin binding is heavily dependent on the presence of histone acetylation in the genome. Altogether, this work provides new insights into a poorly understood chromatin regulator which plays critical roles during stress responses.
Online Signature Verification based on the Lagrange formulation with 2D and 3D robotic models
Creators: name: Diaz, Moises
name: Ferrer, Miguel A.
name: Gil, Juan M.
name: Rodriguez, Rafael
name: Zhang, Peirong
name: Jin, Lianwen
Publisher: name: arXiv
Year: 2025
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Online Signature Verification commonly relies on function-based features, such as time-sampled horizontal and vertical coordinates, as well as the pressure exerted by the writer, obtained through a digitizer. Although inferring additional information about the writers arm pose, kinematics, and dynamics based on digitizer data can be useful, it constitutes a challenge. In this paper, we tackle this challenge by proposing a new set of features based on the dynamics of online signatures. These new features are inferred through a Lagrangian formulation, obtaining the sequences of generalized coordinates and torques for 2D and 3D robotic arm models. By combining kinematic and dynamic robotic features, our results demonstrate their significant effectiveness for online automatic signature verification and achieving state-of-the-art results when integrated into deep learning models.
Supplemental Material, Online_Supplement_SMR799382 - Scaling Sensitive Factorial Survey Analysis
Creators: name: Lang, Volker
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: Sociology

description: Supplemental Material, Online_Supplement_SMR799382 for Scaling Sensitive Factorial Survey Analysis by Volker Lang in Sociological Methods & Research
Using Environmental DNA to Study Brook Trout Populations in the Headwaters of the Chesapeake Bay
Creators: name: Raza, Aiman
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Brook Trout
eDNA
Environmental DNA

description: Brook Trout (Salvelinus fontinalis), a cold-freshwater species native to eastern North America, are bioindicators of cold, clean water. Recent restoration efforts require improved monitoring methods to assess progress toward conservation goals. Environmental DNA (eDNA) is a potentially rapid, cost-effective method to detect Brook Trout presence from water samples. However, eDNA dynamics in aquatic ecosystems are not well understood for this species. We assessed how water temperature, distance from an eDNA source, and filter pore size affect Brook Trout eDNA concentrations. We found significantly higher Brook Trout eDNA concentration at 20 ? compared to 10 ? in a lab experiment. We were unable to obtain quantifiable eDNA concentration in a natural stream setting, likely due to insufficient water volume collection or filter material. This study highlights the importance of optimized eDNA collection methods for accurate and effective species detection to identify priority restoration streams for Brook Trout conservation.
In Defence of Principlism in AI Ethics and Governance
Creators: name: Seger, Elizabeth
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Commentary
Principlism
AI governance
Biomedical ethics
Cultural norms
Ethics washing

description: AbstractIt is widely acknowledged that high-level AI principles are difficult to translate into practices via explicit rules and design guidelines. Consequently, many AI research and development groups that claim to adopt ethics principles have been accused of unwarranted “ethics washing”. Accordingly, there remains a question as to if and how high-level principles should be expected to influence the development of safe and beneficial AI. In this short commentary I discuss two roles high-level principles might play in AI ethics and governance. The first and most often discussed “start-point” function quickly succumbs to the complaints outlined above. I suggest, however, that a second “cultural influence” function is where the primary value of high-level principles lies.
Sustainability Analysis Patterns for Process Mining and Process Modelling Approaches
Creators: name: Fritsch, Andreas
Publisher: name: arXiv
Year: 2025
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Business Process Management (BPM) has the potential to help companies manage and reduce their activities' negative social and environmental impacts. However, so far, only limited capabilities for analysing the sustainability impacts of processes have been integrated into established BPM methods and tools. One of the main challenges of existing Sustainable BPM approaches is the lack of a sound conception of sustainability impacts. This paper describes a set of sustainability analysis patterns that integrate BPM concepts with concepts from existing sustainability analysis methods to address this challenge. The patterns provide a framework to evaluate and develop process modelling and process mining approaches for discovering, analysing and improving the sustainability impacts of processes. It is shown how the patterns can be used to evaluate existing process modelling and process mining approaches.
POLYCYCLIC AROMATIC HYDROCARBON-INDUCED DISRUPTION OF ENDOTHELIAL PERMEABILITY
Creators: name: Patel, Shreyas
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Anthracene
Endothelial Cells
Fluorescein
Naphthalene
Polycyclic Aromatic Hydrocarbons
Pyrene

description: Endothelial cells line the interior of vasculature and regulate nutrient exchange while preventing harmful compounds from invading surrounding tissue. Adherens and tight junctions form intercellular junctions that maintain cell-cell adhesion and regulate solute flux between systemic circulation and tissue. These intercellular junctions can be disrupted following exposure to polycyclic aromatic hydrocarbons (PAHs), causing increased permeability in the endothelial barrier. PAHs are ubiquitous pollutants in our surroundings as a consequence of rapid industrialization and heavy reliance on carbon-based fuels. PAH exposure is associated with a myriad of adverse health effects, ranging from skin and eye irritation to cardiovascular disease and cancer. Herein, the permeability of bovine pulmonary artery endothelial cells was examined in vitro following exposure to low molecular weight PAHs. Bovine endothelial barriers demonstrated an average, but not statistically significant, increase in permeability in fluorescein flux assays following exposure to naphthalene, anthracene, and pyrene. The presented data suggests these low molecular weight PAHs can exert an effect on endothelial barrier integrity and function but warrants further optimization to permeability assays and supplemental methods to elucidate the consequences of PAH exposure.
AppendixS3 – Supplemental material for The Binary Bias: A Systematic Distortion in the Integration of Information
Creators: name: Fisher, Matthew
name: Keil, Frank C.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, AppendixS3 for The Binary Bias: A Systematic Distortion in the Integration of Information by Matthew Fisher and Frank C. Keil in Psychological Science
The Concentric Self
Creators: name: Zellhofer, Anna May
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Poetry
Printmaking
Self
Void

description: This introspection of visual art and poetry delves into the profound layers of human existence, likening it to the concentric rings of a tree. Each ring represents an experience, both tangible and intangible, visible and invisible, that shapes the core of the being. The concept of "dendrochronology of self" captures this idea, visually suggesting a method of understanding the being through the examination of life's rings. It speaks to the interconnectedness of the past, present, and future “self”. The word void means to be invalid, empty, and null. When in reference to the body the void, to me, is when the being is not perceived as a subject. This is when your body becomes a number or statistic. I think this equally means that contributions by a person, whatever the contributions may be, are not dignified. The void also represents space, infinity, and nonexistence. The body is made of a culmination of deep-rooted experiences, both bitter and sweet. I visualize life experience as concentric and contour lines in my visual art. I represent the void as black space that engulfs the figure in the exact moment when the corporeal “self” tumbles into symbolic eternity. The focus on the instance of the fall, is a mnemonic visualization of ordinary reality meeting the origin and conclusion of being and existing. Even when existing within the void, emptiness does not wholly consume us.
Appendix_2-_Main_Analyses_Code – Supplemental material for Isolation, Not Loneliness or Cynical Hostility, Predicts Cognitive Decline in Older Americans
Creators: name: Griffin, Sarah C.
name: Mezuk, Briana
name: Williams, Allison Baylor
name: Perrin, Paul B.
name: Rybarczyk, Bruce D.
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Appendix_2-_Main_Analyses_Code for Isolation, Not Loneliness or Cynical Hostility, Predicts Cognitive Decline in Older Americans by Sarah C. Griffin, Briana Mezuk, Allison Baylor Williams, Paul B. Perrin and Bruce D. Rybarczyk in Journal of Aging and Health
Printable logic circuits comprising self-assembled protein complexes.
Creators: name: Qiu, Xinkai
name: Chiechi, Ryan C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/639/638/298/917
/639/301/357/341
/639/638/440/947
/639/925/927/998
/120
/147/3
/128
article

description: This paper describes the fabrication of digital logic circuits comprising resistors and diodes made from protein complexes and wired together using printed liquid metal electrodes. These resistors and diodes exhibit temperature-independent charge-transport over a distance of approximately 10 nm and require no encapsulation or special handling. The function of the protein complexes is determined entirely by self-assembly. When induced to self-assembly into anisotropic monolayers, the collective action of the aligned dipole moments increases the electrical conductivity of the ensemble in one direction and decreases it in the other. When induced to self-assemble into isotropic monolayers, the dipole moments are randomized and the electrical conductivity is approximately equal in both directions. We demonstrate the robustness and utility of these all-protein logic circuits by constructing pulse modulators based on AND and OR logic gates that function nearly identically to simulated circuits. These results show that digital circuits with useful functionality can be derived from readily obtainable biomolecules using simple, straightforward fabrication techniques that exploit molecular self-assembly, realizing one of the primary goals of molecular electronics.
Polyurethane Nanocapsules in TBI Treatment
Creators: name: Ale, Temitope Ayotola
Publisher: name: Maryland Shared Open Access Repository
Year: 2024

description: This study investigates the development and application of polyurethane nanocapsules for the controlled delivery and release of neuroprotective drugs such as Epigallocatechin Gallate (EGCG) and Tempol with the objective of treating Traumatic Brain Injuries (TBIs). TBIs, a major health issue, causing considerable effects on individuals and healthcare systems globally, require innovative treatment approaches due to the intricate nature of the injury and the challenges in delivering drugs across the blood-brain barrier (BBB). This thesis outlines the process of synthesis of polyurethane nanocapsules encapsulating EGCG and Tempol, leveraging their antioxidant and anti-inflammatory properties to reduce the secondary injury phase after a traumatic brain injury. The properties of the nanocapsules were analyzed using dynamic light scattering (DLS), transmission electron microscopy (TEM), and Fourier-transform infrared (FTIR) spectroscopy. The in-vitro release studies highlighted these nanocapsules' potential for both sustained and on-demand drug release, addressing the need for long-term treatment and adaptability in TBI management. This study highlights the potential of drug delivery systems enhanced with nanotechnology in overcoming the blood-brain barrier and improving therapeutic outcomes for TBI patients, paving the way for future clinical applications and advancements in neurotherapeutic interventions.
Acceptability and feasibility of an acceptance and commitment therapy-based guided self-help intervention for weight loss maintenance in adults who have previously completed a behavioural weight loss programme: the SWiM feasibility study protocol
Creators: name: Ahern, Amy
name: Richards, Rebecca
name: Jones, Rebecca A
name: Whittle, Fiona
name: Mueller, Julia
name: Woolston, Jenny
name: Sharp, Stephen J
name: Hughes, Carly A
name: Hill, Andrew J
name: Duschinsky, Robbie
name: Lawlor, Emma Ruth
name: Morris, Stephen
name: Fusco, Francesco
name: Brennan, Alan
name: Bostock, Jennifer
name: Griffin, Simon
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Public health
1506
1724
Telemedicine
Information technology
diabetes & endocrinology

description: Introduction: The cost-effectiveness and long-term health impact of behavioural weight management programmes depends on post-treatment weight-loss maintenance. Growing evidence suggests that interventions using acceptance and commitment therapy (ACT) could improve long-term weight management. We developed an ACT-based, guided self-help intervention to support adults who have recently completed a behavioural weight loss programme. This study will assess the feasibility and acceptability of this type of intervention and findings will inform the development of a full-scale trial. Methods and analysis: This is a pragmatic, randomised, single-blind, parallel group, two-arm, feasibility study with an embedded process evaluation. We will recruit and randomise 60 adults who have recently completed a behavioural weight loss programme to the ACT-based intervention or standard care, using a computer-generated sequence with 2:1 allocation stratified by diabetes status and sex. Baseline and 6-month measurements will be completed using online questionnaires. Qualitative interviews will be conducted with a subsample of participants and coaches about their experiences at 3 (mid-intervention) and 6 (postintervention) months. Feasibility and acceptability of the intervention, and a full-scale trial will be assessed using a number of outcomes, including adherence to, and engagement with the intervention, recruitment and retention rates, proportion of missing data for each outcome measure, participants’ experiences of the intervention and study, and coaches’ experiences of delivering intervention support. Quantitative and qualitative findings will be integrated and summarised to contribute to the interpretation of the main feasibility evaluation findings. Value of information methods will be used to estimate the decision uncertainty associated with the intervention’s cost-effectiveness and determine the value of a definitive trial. Ethics and dissemination: Ethical approval was received from Cambridge South Research Ethics Committee on 15/03/2021 (21/EE/0024). This protocol (V.2) was approved on 19 April 2021. Findings will be published in peer-reviewed scientific journals and communicated to other stakeholders as appropriate. Trial registration number: ISRCTN12685964.
LIGHTWEIGHT MUTUAL AUTHENTICATION PROTOCOLS FOR IOT SYSTEMS
Creators: name: Alkanhal, Mona
Publisher: name: Maryland Shared Open Access Repository
Year: 2024
Subjects: Authentication
IoT
PUF

description: The Internet of Things (IoT) refers to the large-scale internetworking of diverse devices, many of them with very limited computational resources. The IoT connects diverse, resource-limited devices, demanding robust authentication to thwart malicious nodes. Traditional asymmetric cryptography is impractical due to its resource demands. This dissertation opts to fulfill the aforementioned requirements by developing a library of lightweight authentication protocols that caterers forvariant IoT applications. We employ Physical Unclonable Functions (PUFs), leveraging manufacturing variations to create unique device signatures. However, using PUFs for distributed authentication among IoT nodes raises security concerns as the challenge-response exchange is among IoT nodes rather than the secure server and hence becomes subject to increased vulnerability to attacks. Eavesdroppers could exploit this exchange, collecting data for malicious purposes. Encrypting the challenge and response is impractical due to key management overhead. The dissertation tackles the aforementioned challenges. We first develop a novel authentication mechanism that is based on the incorporation of a PUF in each device. Our mechanism enables the challenge bit string intended by a verifier ?y to be inferred by a prover ?x rather than being explicitly sent. The proposed mechanism also obfuscates the shared information to safeguard it from eavesdroppers who strive to model the underlying PUF using machine learning techniques. Secondly, we further combine the advantage of PUFs, and the agility and configurability of physical-layer communication mechanisms, specifically the Multi-Input Multi Output (MIMO) method. We devise a protocol that utilizes an innovative method to counter attackers who might intercept the communication between ?y and ?x and uncover a set of CRPs to model ?x’s PUF. Our protocol encodes the challenge bit using MIMO antennas array in a manner that is controlled by the verifier and that varies overtime. Additionally, We derive a two-factor authentication protocol by pairing Radio Frequency (RF) fingerprints with PUFs, eliminating the need for traditional key-based methods. This approach enhances security by obfuscating PUF responses without cryptographic primitives. Since both the PUF and the RF-fingerprint are based on unintended variations caused by manufacturing, we aim to increase robustness and mitigate the potential effect of noise by applying the fuzzy extractor. Such a protocol omits CRP retention and cryptosystems. All the aforementioned techniques enable mutual authentication of two devices without the involvement of a trusted third party. The experimental results demonstrate the efficacy of the proposed protocols against modeling attacks and impersonation attempts.
Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10.
Creators: name: Guo, Jingxu
name: Liu, Bin
name: Thorikay, Midory
name: Yu, Minmin
name: Li, Xiaoyan
name: Tong, Zhen
name: Salmon, Richard M
name: Read, Randy
name: Ten Dijke, Peter
name: Morrell, Nicholas
name: Li, Wei
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/45/127/1219
/631/80/86/2368
/631/443/592/75/593
/631/535/1266
/101
/82/103
/96/21
/145
/13/95
/82/83
article

description: Heterozygous mutations in BMPR2 (bone morphogenetic protein (BMP) receptor type II) cause pulmonary arterial hypertension. BMPRII is a receptor for over 15 BMP ligands, but why BMPR2 mutations cause lung-specific pathology is unknown. To elucidate the molecular basis of BMP:BMPRII interactions, we report crystal structures of binary and ternary BMPRII receptor complexes with BMP10, which contain an ensemble of seven different BMP10:BMPRII 1:1 complexes. BMPRII binds BMP10 at the knuckle epitope, with the A-loop and β4 strand making BMPRII-specific interactions. The BMPRII binding surface on BMP10 is dynamic, and the affinity is weaker in the ternary complex than in the binary complex. Hydrophobic core and A-loop interactions are important in BMPRII-mediated signalling. Our data reveal how BMPRII is a low affinity receptor, implying that forming a signalling complex requires high concentrations of BMPRII, hence mutations will impact on tissues with highest BMPR2 expression such as the lung vasculature.
Supplemental Material, SPPS727589_suppl_mat - Population- and Individual-Level Changes in Life Satisfaction Surrounding Major Life Stressors
Creators: name: Doré, Bruce
name: Bolger, Niall
Publisher: name: SAGE Journals
Year: 2017
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material, SPPS727589_suppl_mat for Population- and Individual-Level Changes in Life Satisfaction Surrounding Major Life Stressors by Bruce Doré, and Niall Bolger in Social Psychological and Personality Science
Supplementary document for Symmetric gradient-index media reconstruction - 6497858.pdf
Creators: name: Gomez-Correa, Jesús
name: Padilla-Ortiz, Ana
name: Trevino, Juan
name: Jaimes-Nájera, Alfonso
name: Lozano-Crisostomo, Nestor
name: Cornejo-Rodriguez, Alejandro
name: Chavez-Cerda, Sabino
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary document
Elliewix/But-I-Just-Want-To-Make-A-Graph: 1.0
Creators: name: Wickes, Elizabeth
Publisher: name: Zenodo
Year: 2016
Subjects: data librarian, tidy data

description: Which is a semi-snarky title to a workshop actually called "Creating Tidy Data" for the 2016 Midwest Data Librarian Symposium (MDLS). https://mwdatalibrariansymposium.wordpress.com/

Author: Elizabeth Wickes, @elliewix

This deposit is version 1.0, the version presented at MDLS16.
Control and optimisation of rubber mixing in an internal mixer
Creators: name: Kenny, Trevor N.
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Some areas of current relevance to the rubber mixing industry have been explored with a view to maximizing productivity of mixing plant in conjunction with improvement in uniformity of mixea compound properties. Simulation of batch temperature profile is adopted for scaling between BR and 3D Banbury mixers. The emerging procedures, based on work with three natural rubber compounds, gave rise to rubber from the laboratory mixer more ciosely resembling that from the production process, and hence reduced development costs. Three dynamic test methods were also evaluated, showing the Monsanto MDR curemeter to give a good indication of dynamic performance. A theoretical model for real-time control of the internal mixing process proposes mixing to specific torque targets for the mastication and carbon black incorporation stages of the mixing cycle, and to a heat history target for the latter curative distribution stage. Investigations of these two concepts were undertaken with a BR Banbury mixer. A number of uncertainties have prevented the reduction of mixer torque from following material viscosity with the level of precision required for torque control to present advantage over mixing to time. Heat history control was however found to be a viable technique for augmenting uniformity in scorch/cure characteristics of mixed rubber compound. This also demonstrates scope for mixing curatives at temperatures approaching 150°C, showing only a small increase in batch-to- batch variation compared to production mixing to time at just over 100°C. Consequently heat history control has been applied to a production scale 3D Banbury mixer resulting in a reduction of batch-to-batch variation in scorch and cure times from 3.0% to 1.7% coefficient of variation.
Increased basal insulin sensitivity in late pregnancy in women carrying a male fetus: a cohort study.
Creators: name: Petry, Clive
name: Hughes, Ieuan A
name: Ong, Kenneth
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Research
Development
Fetal sex
Gestational diabetes
Insulin secretion
Glucose

description: Funder: National Institute for Health Research Cambridge Biomedical Research Centre
description: BACKGROUND: It has been suggested that fetal sex may be able to modify maternal metabolism and physiology during pregnancy. Recently pregnant women carrying a male fetus were reported to be more insulin sensitive than those carrying females, although related evidence is inconsistent. METHODS: In this study we administered a 75 g oral glucose tolerance test at around week 28 of pregnancy in 813 pregnant women from a contemporary birth cohort (the Cambridge Baby Growth Study), derived surrogate indices of insulin secretion and sensitivity, and related them to the fetal sex. RESULTS: Carrying a male fetus was associated with lower fasting glucose (difference in mean concentrations ≈ 0.1 mmol/L; β' = 0.063; p = 0.02) and insulin (≈ 1.1 pmol/L; β' = 0.075; p = 0.01) concentrations but not with post-load glucose or insulin concentrations. Male fetal sex was also associated with lower HOMA IR (≈ 1.08 units; β' = 0.071; p = 0.02) and higher QUICKI (≈ 1.06 units; β' = 0.080; p = 0.007) values suggesting increased basal insulin sensitivity. There were no differences in indices of insulin secretion, except for the insulin disposition index which was higher in women carrying a male fetus (≈ 1.15 units; β' = 0.090; p = 0.007). Birth weights were higher in male offspring. CONCLUSIONS: Women carrying a male fetus were relatively more insulin sensitive in the fasting state and secreted more insulin relative to this degree of insulin sensitivity. These results are consistent with the idea that the fetal sex may be able to modify the maternal glucose-insulin axis.
Taiwanhormius Belokobylskij 1988
Creators: name: Belokobylskij, Sergey A.
name: Ku, Deokseo
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Taiwanhormius

description: Key to species of the genus Taiwanhormius
1. Parallel vein (CU1a) of fore wing not interstitial to cubital vein (2-CU1), arising from anterior third of the vein (3-CU1) closed brachial (subdiscal) cell distally. Antenna with 23 antennomeres.—POL equal to OD. Ovipositor sheath about 0.7 × as long as metasoma. Body length 2.3 mm.— China (Taiwan) .................................. T. affinis Belokobylskij, 1988
- Parallel vein (CU1a) of fore wing interstitial to cubital vein (2-CU1) (Figs 2A; 4A). Antenna with 17–19 antennomeres (Figs 1A; 3A) ............................................................................................ 2
2. Malar space 1.5 × larger than basal width of mandible (Fig. 3B). Prescutellar depression almost entirely smooth (Fig. 3G). Brachial (subdiscal) cell of fore wing distally closed on level of recurrent vein (m-cu) or rarely weakly before it (Fig. 4A). Nervulus (cu-a) of fore wing distinctly postfurcal to basal vein (1-M). First metasomal tergite weakly rugulose-granulate (Fig. 4B). Body length 1.5–1.9 mm.— China (Taiwan), Japan .......................... T. granulosus Belokobylskij, 1988
- Malar space almost equal to or only weakly larger than basal width of mandible (Fig. 1B). Prescutellar depression rugulose (Fig. 1F). Brachial (subdiscal) cell of fore wing distally closed distinctly before recurrent vein (m-cu) (Fig. 2A). Nervulus (cu-a) of fore wing subinterstitial to basal vein (1-M) or sometimes even weakly antefurcal. First metasomal tergite entirely coarsely rugulose-reticulate and without granulation (Figs 1F; 2B). Body length 1.3–1.8 mm.— South Korea .................................................................................................. T. austrokoreanus sp. nov.
description: Published as part of Belokobylskij, Sergey A. & Ku, Deokseo, 2025, The genus Taiwanhormius Belokobylskij, 1998 (Hymenoptera: Braconidae: Hormiinae) in Korean Peninsula, pp. 451-460 in Zootaxa 5620 (3) on page 459, DOI: 10.11646/zootaxa.5620.3.4, http://zenodo.org/record/15219785
Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Creators: name: Van De Pette, Mathew
name: Dimond, Andrew
name: Galvão, António M
name: Millership, Steven J
name: To, Wilson
name: Prodani, Chiara
name: McNamara, Gráinne
name: Bruno, Ludovica
name: Sardini, Alessandro
name: Webster, Zoe
name: McGinty, James
name: French, Paul MW
name: Uren, Anthony G
name: Castillo-Fernandez, Juan
name: Watkinson, William
name: Ferguson-Smith, Anne C
name: Merkenschlager, Matthias
name: John, Rosalind M
name: Kelsey, Gavin
name: Fisher, Amanda G
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/136/2442
/631/136/2434/1706
/631/337/176/1988
/631/337/176/1968
/631/1647/245/2222
/59/5
/45/91
/64/60
/49/23
/14/19
/45/88
/13/51
article

description: Transmission of epigenetic information between generations occurs in nematodes, flies and plants, mediated by specialised small RNA pathways, modified histones and DNA methylation. Similar processes in mammals can also affect phenotype through intergenerational or trans-generational mechanisms. Here we generate a luciferase knock-in reporter mouse for the imprinted Dlk1 locus to visualise and track epigenetic fidelity across generations. Exposure to high-fat diet in pregnancy provokes sustained re-expression of the normally silent maternal Dlk1 in offspring (loss of imprinting) and increased DNA methylation at the somatic differentially methylated region (sDMR). In the next generation heterogeneous Dlk1 mis-expression is seen exclusively among animals born to F1-exposed females. Oocytes from these females show altered gene and microRNA expression without changes in DNA methylation, and correct imprinting is restored in subsequent generations. Our results illustrate how diet impacts the foetal epigenome, disturbing canonical and non-canonical imprinting mechanisms to modulate the properties of successive generations of offspring.
Supplemental material for The Influence of Hypomania Symptoms on Income in Self-Employment
Creators: name: Wolfe, Marcus T.
name: Patel, Pankaj C.
name: Drover, Will
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business

description: Supplemental material for The Influence of Hypomania Symptoms on Income in Self-Employment by Marcus T. Wolfe, Pankaj C. Patel and Will Drover in Entrepreneurship Theory and Practice
Supplemental Material1 - Supplemental material for Global media flows: A qualitative review of research methods in audio-visual flow studies
Creators: name: Iordache, Catalina
name: Audenhove, Leo Van
name: Loisen, Jan
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, Supplemental Material1 for Global media flows: A qualitative review of research methods in audio-visual flow studies by Catalina Iordache, Leo Van Audenhove and Jan Loisen in International Communication Gazette
Archeological Reconnaissance of the Naval Recreation Center Shoreline on the Patuxent River at Solomons, Calvert County, Maryland (1986.002)
Creators: name: Israel, Stephen
Year: 1986
Subjects: subject: United States of America (Country)
valueUri: https://core.tdar.org/browse/geographic-keyword/384/united-states-of-america-country
subject: Calvert (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/8419/calvert-county
subject: 24009 (Fips Code)
valueUri: https://core.tdar.org/browse/geographic-keyword/8420/24009-fips-code
subject: Maryland (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/2184/maryland-state-territory
subject: Solomon
valueUri: https://core.tdar.org/browse/geographic-keyword/9624/solomon
subject: North America (Continent)
valueUri: https://core.tdar.org/browse/geographic-keyword/2890/north-america-continent
subject: Historic
valueUri: https://core.tdar.org/browse/temporal-keyword/5728/historic
subject: Prehistoric
valueUri: https://core.tdar.org/browse/temporal-keyword/53/prehistoric
subject: Statement For Management
valueUri: https://core.tdar.org/browse/other-keyword/4176/statement-for-management
subject: Site / Settlement
valueUri: https://core.tdar.org/browse/other-keyword/54881/site-settlement
subject: Field Reconnaisance--Intensive
valueUri: https://core.tdar.org/browse/other-keyword/1241/field-reconnaisance-intensive
subject: Archaeological Overview
valueUri: https://core.tdar.org/browse/investigation-type/1/archaeological-overview

description: This resource is the report of a survey conducted at the Naval Recreation Center in Solomon's Island Maryland in 1986. The collection and records are curated at the Maryland Archaeological Conservation Laboratory on behalf of the Navy.
Report: Archaeological Investigations at Fort Point, St. Inigoes Maryland (1992.033)
Creators: name: Smolek, Michael
name: S. Kathleen Pepper
name: Lawrence, John D
Publisher: name: Maryland Historical Trust
Year: 1983
Subjects: subject: 19th Century
valueUri: https://core.tdar.org/browse/temporal-keyword/5536/19th-century
subject: 20th Century
valueUri: https://core.tdar.org/browse/temporal-keyword/4/20th-century
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Domestic Structure or Architectural Complex
valueUri: https://core.tdar.org/browse/site-type/251/domestic-structure-or-architectural-complex
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management
subject: Site Evaluation / Testing
valueUri: https://core.tdar.org/browse/investigation-type/10/site-evaluation-testing
subject: Systematic Survey
valueUri: https://core.tdar.org/browse/investigation-type/12/systematic-survey

description: Report Abstract: 

An archaeological survey on Fort Point at the Naval Electronic Systems Engineering Activity (NESEA), St. Inigoes, Maryland, was conducted because of planned building construction. An archaeological site (18ST325), with Late woodland aboriginal artifacts and historic period artifacts, had been discovered in 1981 at the proposed building location. In addition, Fort Point is the general area of the unlocated circa 1638 St. Inigoes Fort. In order to establish the extent and nature of the archaeological site and to determine the impact of the proposed construction, an intensive archaeological survey was undertaken.

This survey, conducted in the fall of 1982, involved the systematic excavation of shovel tests and detailed analysis of the field results, artifacts recovered, historical documents, oral history, and photographic evidence. Based on oral, archaeological, and photographic evidence, it is apparent that two houses stood on the site, one dating from the second quarter of the 19th century to circa 1920/30 and another from 1920/30 to mid-century. The site is not deemed eligible for the National Register of Historic Places. Further evidence of the Late Woodland aboriginal occupation and the 1638 fort were not discovered. It was determined that no significant archaeological resources exist within the area of proposed construction.
Sensitivity of Diffusion MRI to White Matter Pathology: Influence of Diffusion Protocol, Magnetic Field Strength, and Processing Pipeline in Systemic Lupus Erythematosus.
Creators: name: Kornaropoulos, Evgenios N
name: Winzeck, Stefan
name: Rumetshofer, Theodor
name: Wikstrom, Anna
name: Knutsson, Linda
name: Morgado Correia, Marta
name: Sundgren, Pia C
name: Nilsson, Markus
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Neurology
diffusion MRI
DTI
DKI
ROI-based analysis
ultra-high magnetic field strength (7T)
diffusion processing
white matter fiber-tracts
effect sizes

description: There are many ways to acquire and process diffusion MRI (dMRI) data for group studies, but it is unknown which maximizes the sensitivity to white matter (WM) pathology. Inspired by this question, we analyzed data acquired for diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) at 3T (3T-DTI and 3T-DKI) and DTI at 7T in patients with systemic lupus erythematosus (SLE) and healthy controls (HC). Parameter estimates in 72 WM tracts were obtained using TractSeg. The impact on the sensitivity to WM pathology was evaluated for the diffusion protocol, the magnetic field strength, and the processing pipeline. Sensitivity was quantified in terms of Cohen's d for group comparison. Results showed that the choice of diffusion protocol had the largest impact on the effect size. The effect size in fractional anisotropy (FA) across all WM tracts was 0.26 higher when derived by DTI than by DKI and 0.20 higher in 3T compared with 7T. The difference due to the diffusion protocol was larger than the difference due to magnetic field strength for the majority of diffusion parameters. In contrast, the difference between including or excluding different processing steps was near negligible, except for the correction of distortions from eddy currents and motion which had a clearly positive impact. For example, effect sizes increased on average by 0.07 by including motion and eddy correction for FA derived from 3T-DTI. Effect sizes were slightly reduced by the incorporation of denoising and Gibbs-ringing removal (on average by 0.011 and 0.005, respectively). Smoothing prior to diffusion model fitting generally reduced effect sizes. In summary, 3T-DTI in combination with eddy current and motion correction yielded the highest sensitivity to WM pathology in patients with SLE. However, our results also indicated that the 3T-DKI and 7T-DTI protocols used here may be adjusted to increase effect sizes.
Non-Invasive and Minimally-Invasive Cerebral Autoregulation Assessment: A Narrative Review of Techniques and Implications for Clinical Research.
Creators: name: Sainbhi, Amanjyot Singh
name: Gomez, Alwyn
name: Froese, Logan
name: Slack, Trevor
name: Batson, Carleen
name: Stein, Kevin Y
name: Cordingley, Dean M
name: Alizadeh, Arsalan
name: Zeiler, Frederick A
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Neurology
cerebrovascular autoregulation
computed tomography
dynamic autoregulation
magnetic resonance imaging
near-infrared spectroscopy
positron emission tomography
static autoregulation
Transcranial Doppler

description: The process of cerebral vessels regulating constant cerebral blood flow over a wide range of systemic arterial pressures is termed cerebral autoregulation (CA). Static and dynamic autoregulation are two types of CA measurement techniques, with the main difference between these measures relating to the time scale used. Static autoregulation looks at the long-term change in blood pressures, while dynamic autoregulation looks at the immediate change. Techniques that provide regularly updating measures are referred to as continuous, whereas intermittent techniques take a single at point in time. However, a technique being continuous or intermittent is not implied by if the technique measures autoregulation statically or dynamically. This narrative review outlines technical aspects of non-invasive and minimally-invasive modalities along with providing details on the non-invasive and minimally-invasive measurement techniques used for CA assessment. These non-invasive techniques include neuroimaging methods, transcranial Doppler, and near-infrared spectroscopy while the minimally-invasive techniques include positron emission tomography along with magnetic resonance imaging and radiography methods. Further, the advantages and limitations are discussed along with how these methods are used to assess CA. At the end, the clinical considerations regarding these various techniques are highlighted.
Appendix_Material_online_supp – Supplemental material for Extreme Candidates as the Beneficent Spoiler? Range Effect in the Plurality Voting System
Creators: name: Wang, Austin Horng-En
name: Chen, Fang-Yu
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, Appendix_Material_online_supp for Extreme Candidates as the Beneficent Spoiler? Range Effect in the Plurality Voting System by Austin Horng-En Wang and Fang-Yu Chen in Political Research Quarterly