cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
La Flexibilidad en Sistemas de Fabricación: Caracterización, Marco Conceptual y Recomendaciones para su Implantación
Creators: name: Stegelmeyer, Dirk
Publisher: name: Zenodo
Year: 1996
Subjects: Flexibility, Manufacturing System

description: Resumen
 Para muchas empresas la fabricación se ha convertido hoy en una clave para la superyivencia y el crecimiento. No obstante, la fábrica está expuesta a un entorno cada vez más cambiante y a unas exigencias de los clientes hacia productos personalizados. Esto conduce a la necesidad creciente de rediseñar la fábrica hacia la flexibilidad.
 Varios autores apuntan fracasos en cuanto a la flexibilización en la fábrica. Por esta razón se presenta un trabajo conceptual, que abarca una base científica para el rediseño de la fábrica orientado hacia la flexibilidad. En el trabajo se hace especial hincapié en la operacionalidad y se ejemplifica.
 En principio, se recoge el estado de la disciplina, abarcando la definición de la flexibilidad fabril y las caracterizaciones de la
 flexibilidad propuestas en la bibliografía. Desde allí se desarrolla, apoyándose en el enfoque de sistemas, una caracterización apta de la flexibilidad que describe la flexibilidad en una determinada fábrica o en un taller.
 Posteriormente, se plantea un marco conceptual que relaciona la flexibilidad de un sistema fabril con factores relevantes para la flexibilización como son, por ejemplo, el cliente y la estrategia fabril.
 Asimismo, se propone un procedimiento que incluye la ayuda de herramientas ya conocidas, como es la identificación de una estrategia fabril, la gestión del cambio o el enfoque de procesos, lo que facilita la especificación de la flexibilidad deseada
 para el alcance de los objetivos fabriles anteriormente establecidos.
 Por lo tanto, la caracterización, el marco conceptual y las recomendaciones correspondientes constituyen un apoyo útil para la puesta en práctica de flexibilidad en la fabricación.
MAGIC gamma-ray telescopes hunting for neutrinos and their sources
Creators: name: Gora, Dariusz
name: Bernardini, Elisa
name: Satalecka, Konstancja
name: Noda, Koji
name: Manganaro, Marina
name: López Moya, Marcos
Publisher: name: Humboldt-Universität zu Berlin
Year: 2017
Subjects: subject: 530 Physik

description: The discovery of an astrophysical flux of high-energy neutrinos by the IceCube Collaboration marks a major breakthrough in the ongoing search for the origin of cosmic rays. Presumably, the neutrinos, together with gamma rays, result from pion decay, following hadronic interactions of protons accelerated in astrophysical objects to ultra-relativistic energies. So far, the neutrino sky map shows no significant indication of astrophysical sources. Here, we report first results from follow-up observations, of sky regions where IceCube has detected muon tracks from energetic neutrinos, using the MAGIC telescopes which are sensitive to gamma rays at TeV energies. Furthermore, we show that MAGIC has the potential to distinguish air showers induced by tau neutrinos from the background of hadronic showers in the PeV-EeV energy range, employing a novel analysis method to the data obtained with high-zenith angle observations.
Relativistic ionization probabilities of hydrogenlike ions exposed to intense laser pulses
Creators: name: Ivanova, I. V.
name: Saenz, A.
name: Bondarev, Andrey
name: Maltsev, Ilia
name: Shabaev, Vladimir
name: Telnov, Dmitry A.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2017
Subjects: subject: 530 Physik

description: The relativistic intense-field ionization of heavy hydrogenlike ions is investigated. The investigation is performed by numerical solving of the time-dependent Dirac equation. The interaction of intense laser pulses with ions is considered beyond the dipole approximation. As an example, the ionization probabilities of the hydrogenlike tin ion exposed to a strong laser field are calculated.
Consensus-based identification of factors related to false-positives in ultrasound scanning of synovitis and tenosynovitis
Creators: name: Narita, Akihiro
name: Ogasawara, Michihiro
name: Ohno, Shigeru
name: Kawahito, Yutaka
name: Kawakami, Atsushi
name: Hiromu Ito
name: Suzuki, Takeshi
name: Kaneko, Atsushi
name: Nakamura, Takayuki
name: Nishida, Keiichiro
name: Sumida, Takayuki
name: Koike, Takao
name: Ikeda, Kei
name: Matsushita, Isao
name: Misaki, Kenta
name: Ogura, Takehisa
name: Kamishima, Tamotsu
name: Seto, Yohei
name: Nakahara, Ryuichi
name: Henmi, Mihoko
name: Fukae, Jun
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biological Sciences
Earth and Environmental Sciences
Medicine
Engineering

description: IntroductionWe aimed to identify causes of false-positives in ultrasound scanning of synovial/tenosynovial/bursal inflammation and provide corresponding imaging examples.MethodsWe first performed systematic literature review to identify previously reported causes of false-positives. We next determined causes of false-positives and corresponding example images for educational material through Delphi exercises and discussion by 15 experts who were an instructor and/or a lecturer in the 2013 advanced course for musculoskeletal ultrasound organized by Japan College of Rheumatology Committee for the Standardization of Musculoskeletal Ultrasonography (JCR-CoSMUS).ResultsSystematic literature review identified 11 articles relevant to sonographic false-positives of synovial/tenosynovial inflammation. Based on these studies, 21 candidate causes of false-positives were identified in the consensus meeting. Of these items, 11 achieved a pre-defined consensus (≥ 80 %) in Delphi exercise and were classified as follows: I. Gray-scale assessment (A. Non-specific synovial findings, B. Normal anatomical structures which can mimic synovial lesions due to either their low echogenicity or anisotropy); II. Doppler assessment (A. Intra-articular normal vessels, B. Reverberation). Twenty-four corresponding examples with 49 still and 23 video images also achieved consensus.ConclusionsOur study provides a set of representative images that can help sonographers to understand false-positives in ultrasound scanning of synovitis and tenosynovitis.
MARTINI: Mock Array Radio Telescope Interferometry of the Neutral ISM
Creators: name: Oman, Kyle A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: MARTINI is a modular Python package that takes smoothed-particle hydrodynamics (SPH) simulations of galaxies as input and creates synthetic spatially- and/or spectrally-resolved observations of the 21-cm radio emission line of atomic hydrogen (data cubes). The various aspects of the mock-observing process are divided logically into sub-modules handling the data cube, source galaxy, telescope beam pattern, noise, spectral model and SPH kernel. MARTINI is object-oriented: each sub-module provides a class (or classes) which can be configured as desired. For most sub-modules, base classes are provided to allow for straightforward customization. Instances of each sub-module class are given as parameters to an instance of a main "Martini" class; a mock observation is then constructed by calling a handful of functions to execute the desired steps in the mock-observing process.
description: Peer-reviewed software published in the Journal of Open Source Software (JOSS)
Explainable AI for human and science
Creators: name: Tan, Juntao
Publisher: name: No Publisher Supplied
Year: 2024

description: Artificial Intelligence (AI) goes beyond merely making predictions. Its explainability is crucial not only for enhancing user satisfaction but also for facilitating more effective decision-making. Given the remarkable advancements in AI models and their critical roles in both human-centered applications and scientific research in recent years, the demand for explainable AI has never been greater. Among all available methods for achieving explainable AI, this dissertation focuses on the specialized domain of counterfactual explanations. Counterfactual explanations offer a unique interpretation of systems by providing "what-if" scenarios that illuminate how a given outcome could differ if the system input were altered. The model-agnostic nature of counterfactual explanations makes them exceptionally well-suited for elucidating the intrinsic mechanisms of advanced AI systems. This is particularly critical in an era where such systems, especially those employing deep neural networks, are becoming increasingly opaque and complex. An in-depth investigation is conducted into the applicability of counterfactual explainable AI across both human-centered and science-oriented AI models. Within the context of human-centered AI systems, such as recommender systems, the incorporation of counterfactual explanations can enhance user trust and satisfaction. This is achieved by explaining not only why the system recommends some items, but also what the users can do to change the recommendation results.This approach further enhances user engagement with the system and fosters a more interactive and controllable paradigm for human users. In the scientific field, counterfactual explainable AI offers a valuable contribution. It helps researchers identify key factors behind model predictions in a straightforward manner and promotes trust and credibility in AI-generated outcomes, thereby accelerating both the human comprehension of natural phenomena and the pace of scientific innovation. This dissertation offers a thorough and methodical exploration of counterfactual explainable AI, encompassing its underlying philosophy, stated objectives, methodological framework, practical applications, and evaluation metrics. First, Chapter 1 and Chapter 2 introduce the core objectives of counterfactual explanations and the attributes that define a high-quality counterfactual explanation. The theoretical foundation is largely based on the Occam's Razor principle. Then, Chapter 3 and Chapter 4 outline the methodology for generating counterfactual explanations and explore their usage in human-centered applications such as recommender systems. At last, Chapter 5 and Chapter 6 discuss their use in scientific applications such as molecule property prediction and protein structure prediction, respectively.
title: Stroomatlas Zeebrugge: deelrapport 5. Factual data rapport ADCP-metingen 11/08/2023
Creators: name: Plancke, Yves
name: De Maerschalck, Bart
Publisher: name: Flanders Hydraulics
Year: 2024

description: Title : WL Rapporten. Waterbouwkundig Laboratorium: Antwerpen.
Volume : 23_063_5
Issue :
Pagination : VI, 10 + 27 p. bijl.
Uplink resource allocation optimization for user-centric cell-free MIMO networks
Creators: name: Li, Zehua
name: Adve, Raviraj
Publisher: name: arXiv
Year: 2024
Subjects: subject: Information Theory (cs.IT)
subject: Networking and Internet Architecture (cs.NI)
subject: Systems and Control (eess.SY)
subject: Signal Processing (eess.SP)
subject: Optimization and Control (math.OC)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Mathematics

description: We examine the problem of optimizing resource allocation in the uplink for a user-centric, cell-free, multi-input multi-output network. We start by modeling and developing resource allocation algorithms for two standard network operation modes. The centralized mode provides high data rates but suffers multiple issues, including scalability. On the other hand, the distributed mode has the opposite problem: relatively low rates, but is scalable. To address these challenges, we combine the strength of the two standard modes, creating a new semi-distributed operation mode. To avoid the need for information exchange between access points, we introduce a new quality of service metric to decentralize the resource allocation algorithms. Our results show that we can eliminate the need for information exchange with a relatively small penalty on data rates.
description: To appear in IEEE Transactions on Wireless Communications, 16 pages, 9 figures
Adaptation requirements due to anatomical changes in free-breathing and deep-inspiration breath-hold for standard and dose-escalated radiotherapy of lung cancer patients
Creators: name: Sibolt, Patrik
name: Wiviann Ottosson
name: Sjöström, David
name: Larsen, Christina
name: Behrens, Claus F.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Engineering

description: Background. Radiotherapy of lung cancer patients is subject to uncertainties related to heterogeneities, anatomical changes and breathing motion. Use of deep-inspiration breath-hold (DIBH) can reduce the treated volume, potentially enabling dose-escalated (DE) treatments. This study was designed to investigate the need for adaptation due to anatomical changes, for both standard (ST) and DE plans in free-breathing (FB) and DIBH.Material and methods. The effect of tumor shrinkage (TS), pleural effusion (PE) and atelectasis was investigated for patients and for a CIRS thorax phantom. Sixteen patients were computed tomography (CT) imaged both in FB and DIBH. Anatomical changes were simulated by CT information editing and re-calculations, of both ST and DE plans, in the treatment planning system. PE was systematically simulated by adding fluid in the dorsal region of the lung and TS by reduction of the tumor volume.Results. Phantom simulations resulted in maximum deviations in mean dose to the GTV-T (GTV-T) of −1% for 3 cm PE and centrally located tumor, and + 3% for TS from 5 cm to 1 cm diameter for an anterior tumor location. For the majority of the patients, simulated PE resulted in a decreasing GTV-T with increasing amount of fluid and increasing GTV-T for decreasing tumor volume. Maximum change in GTV-T of -3% (3 cm PE in FB for both ST and DE plans) and + 10% (2 cm TS in FB for DE plan) was observed. Large atelectasis reduction increased the GTV-T with 2% for FB and had no effect for DIBH.Conclusion. Phantom simulations provided potential adaptation action levels for PE and TS. For the more complex patient geometry, individual assessment of the dosimetric impact is recommended for both ST and DE plans in DIBH as well as in FB. However, DIBH was found to be superior over FB for DE plans, regarding robustness of GTV-T to TS.
Understanding the pathogenesis of abdominal aortic aneurysms
Creators: name: Kuivaniemi, Helena
name: Ryer, Evan J
name: Elmore, James R
name: Tromp, Gerard
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Developmental Biology
Biological Sciences
Earth and Environmental Sciences
Biotechnology
Cell Biology
Medicine
Engineering

description: An aortic aneurysm is a dilatation in which the aortic diameter is ≥3.0 cm. If left untreated, the aortic wall continues to weaken and becomes unable to withstand the forces of the luminal blood pressure resulting in progressive dilatation and rupture, a catastrophic event associated with a mortality of 50–80%. Smoking and positive family history are important risk factors for the development of abdominal aortic aneurysms (AAA). Several genetic risk factors have also been identified. On the histological level, visible hallmarks of AAA pathogenesis include inflammation, smooth muscle cell apoptosis, extracellular matrix degradation and oxidative stress. We expect that large genetic, genomic, epigenetic, proteomic and metabolomic studies will be undertaken by international consortia to identify additional risk factors and biomarkers, and to enhance our understanding of the pathobiology of AAA. Collaboration between different research groups will be important in overcoming the challenges to develop pharmacological treatments for AAA.
Fetal exposures and perinatal influences on the stool microbiota of premature infants
Creators: name: Koestler, Devin C.
name: Housman, Molly L.
name: Hibberd, Patricia L.
name: Moore, Jason H.
name: Morrison, Hilary G.
name: Sogin, Mitchell L.
name: Zain-Ul-Abideen, Muhammad
name: Chernikova, Diana A.
name: Hoen, Anne Gatewood
name: Madan, Juliette C.
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Engineering

description: Objective: To test the hypothesis that maternal complications significantly affect gut colonization patterns in very low birth weight infants.Methods: Forty-nine serial stool samples were obtained weekly from nine extremely premature infants enrolled in a prospective longitudinal study. Sequencing of the bacterial 16S rRNA gene from stool samples was performed to approximate the intestinal microbiome. Linear mixed effects models were used to evaluate relationships between perinatal complications and intestinal microbiome development.Results: Subjects with prenatal exposure to a non-sterile intrauterine environment, i.e. prolonged preterm premature rupture of membranes (PPPROM) and chorioamnionitis exposure, were found to have a relatively higher abundance of potentially pathogenic bacteria in the stool across all time points compared to subjects without those exposures, irrespective of exposure to postnatal antibiotics. Compared with those delivered by Caesarean section, vaginally delivered subjects were found to have significantly lower diversity of stool microbiota across all time points, with lower abundance of many genera, most in the family Enterobacteriaceae.Conclusions: We identified persistently increased potential pathogen abundance in the developing stool microbiota of subjects exposed to a non-sterile uterine environment. Maternal complications appear to significantly influence the diversity and bacterial composition of the stool microbiota of premature infants, with findings persisting over time.
Development of tea tree oil-loaded liposomal formulation using response surface methodology
Creators: name: Ge, Yan
name: Mingqiao Ge
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Neuroscience
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: The aim of this study is to prepare tea tree oil liposome (TTOL) and optimize the preparation condition by single factor experiment and statistical design. TTOL was prepared using a thin-film hydration with the combination of sonication method and the preparation conditions of TTOL were optimized with response surface methodology (RSM). The optimal preparation conditions for TTOL by response surface methodology were as follows: the mass ratio of PC and Cho 5.51, TTO concentration 1.21% (v/v) and Tween 80 concentration 0.79% (v/v). The response surface analysis showed that the significant (p p > 0.05) lack of fit for the reduced models. Furthermore, the interaction of the mass ratio of PC/Cho and TTO concentration had a significant effect. The amounts of Tween 80 required were also reduced with RSM. Under these conditions, the experimental encapsulation efficiency of TTOL was 97.81 ± 0.33%, which was close with the predicted value. Therefore, the optimized preparation condition was very reliable. The increased entrapment efficiency would significantly improve the TTO stability and bioavailability.
Near field iToF LIDAR depth improvement from limited number of shots
Creators: name: Nagiub, Mena
name: Beuth, Thorsten
name: Sistu, Ganesh
name: Gotzig, Heinrich
name: Eising, Ciarán
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 4612
subject: Software engineering

description: Indirect Time of Flight LiDARs can indirectly calculate the scene’s depth from the phase shift angle between transmitted and received laser signals with amplitudes modulated at a predefined frequency. Unfortunately, this method generates ambiguity in calculated depth when the phase shift angle value exceeds 2π. Current state-of-the-art methods use raw samples generated using two distinct modulation frequencies to overcome this ambiguity problem. However, this comes at the cost of increasing laser components’ stress and raising their temperature, which reduces their lifetime and increases power consumption. In our work, we study two different methods to recover the entire depth range of the LiDAR using fewer raw data sample shots from a single modulation frequency with the support of sensor’s gray scale output to reduce the laser components’ stress and power consumption.
TMBIM6 (transmembrane BAX inhibitor motif containing 6) Enhances Autophagy and Reduces Renal Dysfunction in a Cyclosporine A-induced nephrotoxicity model
Creators: name: Yadav, Raj Kumar
name: Geum-Hwa Lee
name: Lee, Hwa-Young
name: Li, Bo
name: Han-Eul Jung
name: Harun-Or Rashid
name: Choi, Min Kyung
name: Binod Kumar Yadav
name: Woo-Ho Kim
name: Kyung-Woon Kim
name: Byung-Hyun Park
name: Kim, Won
name: Lee, Yong-Chul
name: Hyung-Ryong Kim
name: Han-Jung Chae
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Marine Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Meta Science
subject: Chemistry
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry

description: Cyclosporine A (CsA) is widely used as an immunosuppressor in transplantation. Previous studies reported that CsA induces autophagy and that chronic treatment with CsA results in accumulation of autophagosomes and reduced autophagic clearance. Autophagy is a prosurvival process that promotes recovery from acute kidney injury by degrading misfolded proteins produced in the kidney. In the present study, we used TMBIM6-expressing HK-2, human kidney tubular cells (TMBIM6 cells) and Tmbim6 knockout (tmbim6−/-) mice. When exposed to CsA, the TMBIM6 cells maintained autophagy activity by preventing autophagosome accumulation. With regard to signaling, PRKKA/AMPK phosphorylation and mechanistic target of rapamycin (serine/threonine kinase) complex 1 (MTORC1) expression and its downstream target TFEB (transcription factor EB), a lysosome biogenesis factor, were regulated in the TMBIM6 cells. Lysosomal activity was highly increased or stably maintained in the presence of TMBIM6. In addition, treatment of tmbim6−/-mice with CsA resulted in increased autophagosome formation and decreased lysosome formation and activity. We also found that tmbim6−/-mice were susceptible to CsA-induced kidney injury. Taken together, these results indicate that TMBIM6 protects against CsA-induced nephrotoxicity both in vitro and in vivo by inducing autophagy and activating lysosomes.
Presentation of the Polish National Chapter at the CoARA National Chapters Exchange Forum 2024
Creators: name: Kistryn, Stanislaw
Publisher: name: Zenodo
Year: 2024

description: Slides presented at the CoARA National Chapters Exchange Forum 2024.  A description of the event is available here: https://coara.eu/news/building-a-stronger-network-coara-national-chapters-convene-for-a-first-exchange-forum/.
MEMORY INSTITUTIONS MEET AI:
Creators: name: Famularo, Jordan
name: Denton, Remi
Publisher: name: International Journal for Digital Art History
Year: 2024

description: Galleries, libraries, archives, and museums (GLAMs) across the globe are building new datasets to render their collections machine-readable and internet-accessible. The new generation of GLAM datasets have wide reach, offering to turn institutions inside-out so that remote audiences can view, download, share, and remix digital assets. GLAM institutions have treated the associated machine learning (ML) and artificial intelligence (AI) technologies as neutral or even inherently positive, able to promote cultural understanding and appreciation in ways that promise scale, openness, and customization. However, some critics suggest that the upside of data-driven technologies needs to be balanced with risks that arise from their design, development, and deployment. 

In this work we ask: how do GLAMs account for the implications of offering AI-driven services? We seek to answer the question by flagging key ethics and governance issues in tandem with supplying some guardrails for navigating them. Our approach focuses on GLAM datasets as sociotechnical systems. Drawing on our experiences as researchers spanning multiple areas (computer science, computer vision, AI ethics, art history, and cybersecurity) and working in different sectors (industry and academia), we identify salient concerns and remediations from critical technology discourse on dataset development for AI and ML systems. 
description: International Journal for Digital Art History, No. 9 (2023): "Dear ChatGPT, Give Us A Title!" Responsiveness and Responsibility in Times of AI
Generalized Dynamic Principal Components
Creators: name: Peña, Daniel
name: Yohai, Victor J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: Brillinger defined dynamic principal components (DPC) for time series based on a reconstruction criterion. He gave a very elegant theoretical solution and proposed an estimator which is consistent under stationarity. Here, we propose a new enterally empirical approach to DPC. The main differences with the existing methods—mainly Brillinger procedure—are (1) the DPC we propose need not be a linear combination of the observations and (2) it can be based on a variety of loss functions including robust ones. Unlike Brillinger, we do not establish any consistency results; however, contrary to Brillinger’s, which has a very strong stationarity flavor, our concept aims at a better adaptation to possible nonstationary features of the series. We also present a robust version of our procedure that allows to estimate the DPC when the series have outlier contamination. We give iterative algorithms to compute the proposed procedures that can be used with a large number of variables. Our nonrobust and robust procedures are illustrated with real datasets. Supplementary materials for this article are available online.
Pulse pressure amplification and its determinants
Creators: name: Pichler, Gernot
name: Martinez, Fernando
name: Vicente, Antonio
name: Solaz, Elena
name: Calaforra, Oscar
name: Redon, Josep
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Marine Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Physiology
subject: Molecular Biology
subject: Cell Biology

description: Background. Pulse pressure (PP) amplification expressed as the peripheral-to-central PP ratio has gained importance in the assessment of cardiovascular phenotypes and cardiovascular risk. The aim of the present study was to assess the relationship between PP amplification, large vessel parameters and peripheral blood pressure (BP) to gain insights into the amplification phenomenon. Methods. Peripheral BP, central BP and carotid-femoral pulse wave velocity (cfPWV) were assessed using the OMRON M6, SphygmoCor and Complior devices, respectively, in 741 adults attending the hypertension outpatient clinic. Analysis of covariance, partial correlations and multiple linear regression models were performed to assess the relationship between PP amplification, peripheral BP and cfPWV. Results. PP amplification was inversely related to BP group. Women showed lower PP amplification than men (1.24 ± 0.18 and 1.35 ± 0.18, respectively, p < 0.001). Age, female gender and mean arterial pressure were inversely associated with PP amplification (p < 0.001), whereas heart rate and body mass index showed positive associations (p < 0.001 and p = 0.049, respectively). cfPWV was a predictor of PP amplification in men but not in women (p = 0.006 and p = 0.424, respectively). Conclusions. PP amplification is related to BP: the higher the BP, the lower the PP amplification. Gender, age and body composition have a significant impact on PP amplification.
title: Naturalising perceived otherness
title: Embodied patterns of violence
titleType: Subtitle
Creators: name: Niehus-Kettler, Melinda
Publisher: name: Universität Potsdam
Year: 2024
Subjects: subject: 300 Sozialwissenschaften

description: This essay takes an Anglophone Cultural Studies approach to reflect on the interdependence among as well as the individual (implicit) impact of the elements constituting our (embodied) power structures. These are, e.g., bodily experience/s such as shame and fear, everyday and institutional discourses and practices, but also manifestations of differences and particularities that we transform into phenomena such as “norms”, “binary systems” and “binary organisations”. The analysis of seemingly cyclic “Othering processes” and patterns of violence shows how people who identify as trans*, inter*, or non-binary have to live through and embody epistemological, emotional, and/or physical violence. At the same time, the descriptions illustrate numberless potential forms of resistance and change.
description: Zweitveröffentlichungen der Universität Potsdam : Philosophische Reihe; 188
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model
Creators: name: Yadav, Raj Kumar
name: Geum-Hwa Lee
name: Lee, Hwa-Young
name: Li, Bo
name: Han-Eul Jung
name: Harun-Or Rashid
name: Choi, Min Kyung
name: Binod Kumar Yadav
name: Woo-Ho Kim
name: Kyung-Woon Kim
name: Byung-Hyun Park
name: Kim, Won
name: Lee, Yong-Chul
name: Hyung-Ryong Kim
name: Han-Jung Chae
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Marine Biology
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Meta Science
subject: Chemistry
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry

description: Cyclosporine A (CsA) is widely used as an immunosuppressor in transplantation. Previous studies reported that CsA induces autophagy and that chronic treatment with CsA results in accumulation of autophagosomes and reduced autophagic clearance. Autophagy is a prosurvival process that promotes recovery from acute kidney injury by degrading misfolded proteins produced in the kidney. In the present study, we used TMBIM6-expressing HK-2, human kidney tubular cells (TMBIM6 cells) and Tmbim6 knockout (tmbim6−/−) mice. When exposed to CsA, the TMBIM6 cells maintained autophagy activity by preventing autophagosome accumulation. With regard to signaling, PRKKA/AMPK phosphorylation and mechanistic target of rapamycin (serine/threonine kinase) complex 1 (MTORC1) expression and its downstream target TFEB (transcription factor EB), a lysosome biogenesis factor, were regulated in the TMBIM6 cells. Lysosomal activity was highly increased or stably maintained in the presence of TMBIM6. In addition, treatment of tmbim6−/− mice with CsA resulted in increased autophagosome formation and decreased lysosome formation and activity. We also found that tmbim6−/− mice were susceptible to CsA-induced kidney injury. Taken together, these results indicate that TMBIM6 protects against CsA-induced nephrotoxicity both in vitro and in vivo by inducing autophagy and activating lysosomes.
World music in the elementary and junior high general music curriculum : an analysis from an ethnomusicological perspective
Creators: name: Hunt, Lilian Wong
Publisher: name: The University of Texas at Austin
Year: 1984
Subjects: subject: World music--Study and teaching (Elementary)
subject: World music--Study and teaching (Middle school)
subject: Ethnomusicology

description: Time and emphasis are not the only determinants of whether the teaching of world music makes its potential contribution to the goals of music education and the education process in general. It must be used and taught effectively. At present the music teacher's primary source of information concerning world music and how to use it is found in music textbooks. Thus a satisfactory presentation of world music depends primarily upon the quality of the textbooks and secondarily upon the quality of supplemental resources. This is both with regards to their content, and with regards to the assistance they give the teacher in using that content. Besides improvements in the quality of textbooks a broadening of the music teacher's training would obviously be helpful. Exposure to ethnomusicology, and training in the use and teaching of world music could make a significant impact on the quality of music education by making teachers less dependent on the texts as a source of didactic help, and more independent in structuring their teaching to meet various situations. The aims of this paper are to evaluate the present method of teaching world music in the elementary and junior high general music classes, to examine the historical development of world music as a component of general music curriculum, to see how teaching world music fulfills the objectives and philosophy of music education, to ascertain its present status, and to look at the direction it is following or may need to follow
title: Staged angioplasty and stenting for post-transplant renal artery stenosis
Creators: name: Kathar Hussain, Mohamed Rafi
Publisher: name: EURORAD
Year: 2024
Subjects: subject: Interventional radiology
subject: Interventional vascular
subject: Kidney
subject: Angioplasty
subject: Stents
subject: Clinical Case

description: Clinical History: A 40-year-old female, a known case of chronic kidney disease stage IV, post-1-year renal transplant, came with complaints of fever on and off, breathlessness, and a productive cough for the past 1 week. Serum creatinine increased from 1.8 to 2.2. Doppler USG of the transplanted kidney is abnormal and diagnosed as graft dysfunction.

description: 40 years, female
Re-telling the stories of artists who are women : lessons from the multimedial fictions of George Sand
Creators: name: McTurk-Starkie, Amy
Publisher: name: The University of St Andrews
Year: 2024
Subjects: subject: George Sand
subject: Women artists
subject: Lived experience
subject: Women's artistic agency
subject: Women's creativity
subject: Narrative strategies
subject: Narrative clash
subject: Multiple art forms
subject: Nineteenth-century France
subject: Literary representation of the artist
subject: PQ2419.M3
subject: Sand, George, 1804-1876--Criticism and interpretation
subject: Women artists--France--19th century

description: This study analyses George Sand’s depictions of artists as women creating in multiple art forms (as writers, actresses, musicians, and painters) to disclose Sand’s innovative narrative strategies that allow alternative stories about women’s creativity to emerge against a background of major medical, political, and cultural discourses that insistently rendered prevalent understandings of womanhood antithetical to artistic vocation. Challenging the tendency to read Sand’s women artists primarily through the lens of sex or gender for the production of (equally reifying) counter-stereotypes, the multimedial scope of this thesis – which addresses the lack of any major study of Sand’s female artists across art forms – demonstrates how recentring the agency and creativity possessed by Sand’s situated heroines reveals key alternative forms of women’s artistic practice within their nineteenth-century contexts. This thesis reveals how Sand’s fiction repeatedly functions as an extensive exploration of the lived experiences of women creating in a particular art form. Reading Sand’s stories of women artists for the narrative clashes that occur between her female artists’ testimony of lived experience and the dominant cultural narratives for both “the Artist” and “the Woman” highlights how Sand’s texts rewrite these dominant narratives to reflect better the lived experiences of female artists in nineteenth-century France. Consequently, my thesis addresses the dissonance between predominant representations of creative women participating in the cultural sphere (whether as monstrous Bas-bleu, frivolous dabbler, or muse) and the lived experiences of women artists, who were increasingly present and successful in the cultural sphere. Sand’s depictions of artists as women thus not only provide models for women’s artistic identities, but more importantly, demonstrate strategies through which women could continually produce interspaces for the development of their artistic identity as a response to, and a negotiation of, the historically framed contexts that allegedly defined them.
Rehabilitation and return to activity criteria after operative management of chronic exertional compartment syndrome of the leg: a systematic review
Creators: name: Gawel, Richard J.
name: Kemler, Bryson R.
name: Coladonato, Carlo
name: Freedman, Kevin B.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Mental Health

description: Endurance athletes with chronic exertional compartment syndrome (CECS) frequently require fasciotomy to return to activity, but there are no existing comprehensive evidence-based rehabilitation guidelines. We aimed to summarize rehabilitation protocols and return to activity criteria after CECS surgery. Through a systematic literature review, we identified 27 articles that explicitly defined physician-imposed restrictions or guidelines for patients to resume athletic activities following CECS surgery. Common rehabilitation parameters included running restrictions (51.9%), postoperative leg compression (48.1%), immediate postoperative ambulation (44.4%), and early range of motion exercises (37.0%). Most studies (70.4%) reported return to activity timelines, but few (11.1%) utilized subjective criteria for guiding return to activity. No studies utilized objective functional criteria. Rehabilitation and return to activity guidelines after CECS surgery remain poorly defined, and further investigation is needed to develop such guidelines that will enable endurance athletes to safely return to activities and minimize recurrence.
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model
Creators: name: Yadav, Raj Kumar
name: Geum-Hwa Lee
name: Lee, Hwa-Young
name: Li, Bo
name: Han-Eul Jung
name: Harun-Or Rashid
name: Choi, Min Kyung
name: Binod Kumar Yadav
name: Woo-Ho Kim
name: Kyung-Woon Kim
name: Byung-Hyun Park
name: Kim, Won
name: Lee, Yong-Chul
name: Hyung-Ryong Kim
name: Han-Jung Chae
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Cyclosporine A (CsA) is widely used as an immunosuppressor in transplantation. Previous studies reported that CsA induces autophagy and that chronic treatment with CsA results in accumulation of autophagosomes and reduced autophagic clearance. Autophagy is a prosurvival process that promotes recovery from acute kidney injury by degrading misfolded proteins produced in the kidney. In the present study, we used TMBIM6-expressing HK-2, human kidney tubular cells (TMBIM6 cells) and Tmbim6 knockout (tmbim6−/−) mice. When exposed to CsA, the TMBIM6 cells maintained autophagy activity by preventing autophagosome accumulation. With regard to signaling, PRKKA/AMPK phosphorylation and mechanistic target of rapamycin (serine/threonine kinase) complex 1 (MTORC1) expression and its downstream target TFEB (transcription factor EB), a lysosome biogenesis factor, were regulated in the TMBIM6 cells. Lysosomal activity was highly increased or stably maintained in the presence of TMBIM6. In addition, treatment of tmbim6−/− mice with CsA resulted in increased autophagosome formation and decreased lysosome formation and activity. We also found that tmbim6−/− mice were susceptible to CsA-induced kidney injury. Taken together, these results indicate that TMBIM6 protects against CsA-induced nephrotoxicity both in vitro and in vivo by inducing autophagy and activating lysosomes.
title: Energiesystemmodellierung von Kasernen
Creators: name: Blankenstein, Benjamin
Publisher: name: FH Münster - University of Applied Sciences
Year: 2024

description: Die Planung urbaner Energiesysteme wird durch die zunehmende Verbreitung sektorgekoppelter Technologien und neuer Verbrauchssektoren immer komplexer. Klassische Planungsmethoden kommen an ihre Grenzen. Die Energiesystemmodellierung (ESM) bietet eine Möglichkeit, ein Energiesystem hinsichtlich der Kosten und der Treibhausgas (THG)- Emissionen zu optimieren. Gleichzeitig ergibt sich aus der Energiewende und angestrebten THG-Neutralität ein akuter Handlungsbedarf. Dies gilt auch für die 1 500 Kasernen in Deutschland. Im Rahmen dieser Arbeit werden der bestehende Modellierungsprozess des Spreadsheet Energy System Model Generator (SESMG) erweitert, indem Herausforderungen der Modellierung und Optimierung von Kasernen identifiziert und Lösungsansätze hierzu entwickelt werden.
Diese Arbeit basiert auf der ESM einer realen Kaserne. Es kann das Urban District Upscaling Tool zur Erstellung der für den SESMG benötigten Modelldefinition verwendet werden. Die Open-Source Datenbank SESMG-Data, kann automatisch die benötigte Standard Parameter Tabelle mit zugehörigem Bericht generieren. Weiterhin wurde ein Energieaustauschmodell vorgestellt, das den Energieaustausch zwischen Kasernen eines Bilanzkreises ermöglicht. Ein Fokus liegt auf der Abbildung zukünftiger Ausbaupläne.
Dazu wurden kasernenspezifische Gebäudeprofile entwickelt, die gemittelte spezifische Energiebedarfe und weitere Parameter zur Berechnung der Wand-, Fenster-, und Dachfläche enthalten. Der spezifische Wärmebedarf kann durch einen Faktor an die Baualtersklasse angepasst werden. Mit Hilfe statistischer Kennwerte lässt sich ein geeignetes Standardlastprofil für verschiedene Gebäudeprofile auswählen. Zur Reduktion der Komponenten im Energiesystemoptimierungsmodell (ESOM) können die Dachflächenpotenziale von Photovoltaikanlagen zusammengefasst werden. Da Kasernen nur eine Bilanzgrenze besitzen, können zudem auch die Strombedarfe der einzelnen Gebäude zusammengefasst werden. Damit lassen sich gleichzeitig dezentrale Batteriespeicher als Komponente des ESOMs ausschließen. Die Potenzialflächen von Erdwärmepumpen können zusammengefasst werden, wobei Abstands- und Belastbarkeitsgrenzen eingehalten werden müssen.
Kasernen verfügen häufig über Bestandswärmenetze, die im ESOM gesondert berücksichtigt werden müssen. Um dieses Bestandswärmenetz abzubilden, können die Verteilleitungen manuell nachgezeichnet werden und in einer Vormodellierung mit dem SESMG mit geringeren Kosten angesetzt werden. Die in dieser Arbeit entwickelten Methoden sind allgemeingültig für Kasernen. Die Übertragbarkeit der kasernenspezifischen Gebäudeprofile ist aufgrund der unterschiedlichen Nutzung von Kasernen nur eingeschränkt möglich. Der bestehende Modellierungsprozess wurde um kasernenspezifische Prozessschritte erweitert und visualisiert. Zukünftige Modellierungen von Kasernen können zur Validierung der Ergebnisse und für weitere Anpassungen, wie z. B. die Erstellung einer kasernenspezifischen Datenbank, genutzt werden.
A Systematic Review on the Effectiveness of Eyewear in Reducing the Incidence and Severity of Eye Injuries in Racket Sports
Creators: name: Mazarelo, James F.D.
name: Winter, Samantha L.
name: Fong, Daniel T.P.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: To assess what eyewear (if any) reduces eye injury incidence and severity in squash, racketball, tennis and badminton. Systematic review following the ‘Preferred Reporting Items for Systematic Reviews and Meta-Analyses’ (PRISMA) and the ‘implementing Prisma in Exercise, Rehabilitation, Sport medicine and SporTs science’ (PERSiST) guidelines. PubMed, SportDiscus and Web of Science were searched on 22nd February 2023. All study types except reviews were eligible. Studies had to report the type of eyewear worn (if any) with a form of eye injury incidence and severity. 364 papers were initially retrieved and after the screening process 29 remained. A subgroup analysis was carried out on studies that had a sample size of five or above, were not only looking at a particular type of eye injury and that had sufficient data to allow the percentage of eye injuries that occurred when no eyewear was worn to be calculated. From this analysis, the median percentage of eye injuries that occurred when no eyewear was worn was found to be 93%. Some of these injuries were serious and required complex treatment. Prescription lenses, contact lenses and industrial eyewear made some injuries more severe. In squash and racketball, lensless eye guards were ineffective as the ball could deform on impact, still making contact with the eye. Only eyewear compliant with updated ASTM (or similar) standards was associated with no eye injuries and so provided adequate protection in all four sports. Although this systematic review only summarizes evidence on injuries requiring hospital treatment, it is recommended that national governing bodies and key decision makers within squash, racketball, tennis and badminton examine the evidence presented and consider extending existing rules or implementing new recommendations and policies on protective eyewear use to reduce eye injury incidence and severity in their sport.
NURIDDIN MUHAMMAD JAHONGIRSHOH VA MALIKA NURJAHONBEGIMLARNING ADABIY KECHALARI TARIXI
Creators: name: Sherxon QORAYEV, Qarshi irrigatsiya va agrotexnologiyalar instituti dotsenti (PhD).
Publisher: name: Zenodo
Year: 2024

description: Boburiy Jahongirshoh nomi bilan mashhur bo‘lgan Shoh Salim ham tariqat namoyandasi - shayx, ham shoir, ham mutafakkir bo‘lgan. Ma’lumotlarga ko‘ra, “yoshi yigirma yettiga to‘lganda o‘sha davrning mashhur avliyo va shayxlarining Allohga qilgan iltijo va duolaridan so‘nggina 1569 yilda Akbarshoh o‘g‘il farzand ko‘rdi. Unga Allohdan o‘g‘il farzand tilab bergan ajmerlik shayx Salim Cheshtiydan minnatdorlik belgisi sifatida tilab olingan shahzodaga Muhammad Salim deb ism qo‘ydilar. Podshoh otasi uni ba’zan erkalatib, “Shayx Bobo” deb ham atardi”.[1] Mutribiy “Tazkirat ush-shuaro”da Jaloliddin Muhammad Akbarshohning farzandi “ulug‘ nomli shahriyor Shayxu podshoh” haqida shunday yozgan: “Nihoyatda oliyhimmat podshoh bo‘lib, fazl ahliga juda yaxshi rioyat va tarbiyatlar ko‘rguzardi. Jannat oyin-qoidali majlisi doimo olim va solih odamlarga to‘la bo‘lardi.

[1] Satimov G‘. Boburiyzodalar. T.: Sharq NMAK BT, 2016.-B.46.