cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Real world treatment utilization patterns in patients with castration-resistant prostate cancer
Creators: name: Vigneswaran, Hari T.
name: Warnqvist, Anna
name: Andersson, Therese M. L.
name: Leval, Amy
name: Eklund, Martin
name: Nordström, Tobias
name: Eloranta, Sandra
name: Schain, Frida
name: Dearden, Lindsay
name: Liwing, Johan
name: Mehra, Maneesha
name: Nair, Sandhya
name: Pettersson, Andreas
name: Akre, Olof
name: Aly, Markus
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Plant Biology

description: Studies describing treatment utilization for castration-resistant prostate cancer (CRPC) are limited. We aimed to describe the treatment utilization of a contemporary population-based CRPC cohort between 2006 and 2016. We identified 1699 men with a PC diagnosis between 2005 and 2015, who developed CRPC between 2006 and 2015 in the Stockholm region of Sweden. Demographic information, stage and grade at PC diagnosis, stage at CRPC, prostate-specific antigen (PSA) nadir, PSA doubling time, treatment utilization rate within 1 year of CRPC diagnosis, reason for stopping therapy, treatment sequence trajectory, overall and PC specific survival was described. Treatment for men with de novo metastatic disease (n = 463) was 32%, treatment for men with progressive metastatic disease after PC diagnosis (n = 66) was 44%, treatment for men with nonmetastatic CRPC (n = 113) was 34% and treatment for those with an unknown stage at time of CRPC diagnosis (n = 857) was 12%. Docetaxel was used in 39%, abiraterone acetate plus prednisone in 15%, enzalutamide in 13%, cabazitaxel in 11% and radium-223 in 5% of treatments. Treatment increased from 22% in 2006–2009 for metastatic cancer to 50% in 2013–2015 (p 3 months (OR: 0.4, 95% CI: 0.3 − 0.6) and a diagnosis between 2013 and 2015 (OR: 3.4, 95% CI: 2.0 − 5.8). Despite treatment availability, in this large real-world cohort we found treatment utilization to remain low.
Production, characterization, and biodistribution of lignin-capped silver nanoparticles to combat multidrug resistant bacteria in vitro and in vivo
Creators: name: Asnis, Jason
Publisher: name: University of British Columbia
Year: 2018

description: One of the most important issues in healthcare today is the development of bacterial resistance to antibiotics which has created a generation of bacteria known as multidrug resistant (MDR) bacteria. Due to antibiotics’ inability to treat these MDR bacteria metal and metal oxide nanoparticles have been gaining interest as antimicrobial agents. Among those, silver nanoparticles have been used extensively as broad spectrum antimicrobial agents. Here we describe the production and characterization of silver nanoparticles made from the wood biopolymer lignin as a reducing and capping agent with excellent antimicrobial activity against MDR bacteria both in vitro and in vivo. We describe and compare the productions of these lignin-capped silver nanoparticles (L-AgNPs) both through a standard heating procedure and through a microwave-assisted synthesis. The L-AgNPs have been radioactively labeled using both iodine-123 and the novel radioisotope silver-111 to determine their biodistribution by SPECT/CT imaging after subcutaneous injection or intratracheal instillation. The particles were then tested for in vitro antimicrobial activity by broth dilution against a variety of Gram-positive and Gram-negative MDR clinical isolate bacterial strains and ATCC strains. They were also tested for efficacy in an in vivo cutaneous infection (abscess) model caused by biofilm-forming MDR bacterial strains. The particles were produced using a simple, one-pot synthesis method and characterized by ultraviolet-visual spectroscopy, dynamic light scattering, x-ray diffraction, and scanning transmission electron microscopy. Characterization of the lignin-capped silver nanoparticles shows uniform spherical nanoparticles with a silver core and a lignin coating with a diameter of about 50 nm for both synthesis methods, but the microwave method was significantly faster (10 min vs. 3 days). The particles radioactively labeled with silver-111 were visible on SPECT/CT and were labeled with high efficiency, but produced a poor size distribution. The L-AgNPs radioactively labeled with iodine-123 and injected subcutaneously remained at the injection site up to 48 hours post-injection. The in vitro minimum inhibitory concentration (MIC) of L-AgNPs was ≤5 µg/mL for all tested bacterial strains, and a significant decrease in both abscess size and bacterial load was observed against in vivo infections caused by MDR strains of S. aureus and P. aeruginosa.
Cotunneling thermopower of single electron transistors
Creators: name: Turek, Marko
name: Matveev, K. A.
Publisher: name: Universität Regensburg
Year: 2002
Subjects: subject: 530 Physik

description: We study the thermopower of a quantum dot weakly coupled to two reservoirs by tunnel junctions. At low temperatures the transport through the dot is suppressed by charging effects (Coulomb blockade). As a result the thermopower shows an oscillatory dependence on the gate voltage. We study this dependence in the limit of low temperatures where transport through the dot is dominated by the processes of inelastic cotunneling. We also obtain a crossover formula for intermediate temperatures which connects our cotunneling results to the known sawtooth behavior in the sequential tunneling regime. As the temperature is lowered, the amplitude of thermopower oscillations increases, and their shape changes qualitatively.
Spectral evolution of long Gamma Ray Burst prompt emission: electrostatic acceleration and adiabatic expansion
Creators: name: Massaro, F.
name: Grindlay, J. E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Despite the great variation in the light curves of Gamma Ray Burst (GRB) prompt emission, their spectral energy distribution is generally curved and broadly peaked. In particular, their spectral evolution is well described by the hardness-intensity correlation during a single pulse decay phase, when the SED peak height S_p decreases as its peak energy E_p decreases. We propose an acceleration scenario, based on electrostatic acceleration, to interpret the E_p distribution peak at ~ 0.25 MeV. We show that during the decay phase of individual pulses in the long GRB light curve, the adiabatic expansion losses likely dominate the synchrotron cooling effects. The energy loss as due to adiabatic expansion can also be used to describe the spectral evolution observed during their decay phase. The spectral evolution predicted by our scenario is consistent with that observed in single pulses of long BATSE GRBs.
description: 4 pages, 3 figures, ApJ Letter accepted
Robotic salvage pelvic lymph node dissection for locoregional recurrence after radical prostatectomy: a single institution experience
Creators: name: Hopland, Olav Andreas
name: Fosså, Sophie D.
name: Ottosson, Fredrik
name: Brennhovd, Bjørn
name: Svindland, Aud
name: Hole, Knut Håkon
name: Hernes, Eivor
name: Eri, Lars Magne
name: Diep, Lien My
name: Berge, Viktor
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: To assess treatment response (PSA < 0.2 ng/ml), need for additional therapy and complication rate after robot assisted salvage pelvic lymph node dissection (sPLND) Analysis of outcomes data from radical prostatectomy (RP) patients consecutively operated with robot assisted sPLND due to biochemical recurrence and positron-emission tomography (PET)/computed tomography (CT)-detected nodal recurrence of pelvic lymph nodes. Sixty-nine patients underwent robotic sPLND after a median time of 47 months post- RP. Sixty-four patients (93%) had malignant lymph nodes upon histological assessment of sPLND specimen. Twenty patients (29%) achieved PSA < 0.2 ng/ml 6 weeks postoperatively. After median (IQR) follow-up of 15 months (10–27), fourteen patients (20%) still had PSA < 0.2 ng/ml without additional therapy and forty-one patients (59%) had started additional therapy. No significant predictor for treatment response was found. Postoperative complications occurred in 14 patients (20%). Eleven of these complications were classified as Clavien-Dindo grade 1 Oncological benefit of sPLND as the only salvage procedure seems to be limited, though almost one third of patients achieved treatment response. Clinical trials are needed to determine if sPLND as part of a multimodal treatment may improve outcome.
A Microscopic View on the Mott transition in Chromium-doped V2O3
Creators: name: Lupi, S.
name: Baldassarre, L.
name: Mansart, B.
name: Perucchi, A.
name: Barinov, A.
name: Dudin, P.
name: Papalazarou, E.
name: Rodolakis, F.
name: Rueff, J. -P.
name: Itié, J. -P.
name: Ravy, S.
name: Nicoletti, D.
name: Postorino, P.
name: Hansmann, P.
name: Parragh, N.
name: Toschi, A.
name: Saha-Dasgupta, T.
name: Andersen, O. K.
name: Sangiovanni, G.
name: Held, K.
name: Marsi, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: V2O3 is the prototype system for the Mott transition, one of the most fundamental phenomena of electronic correlation. Temperature, doping or pressure induce a metal to insulator transition (MIT) between a paramagnetic metal (PM) and a paramagnetic insulator (PI). This or related MITs have a high technological potential, among others for intelligent windows and field effect transistors. However the spatial scale on which such transitions develop is not known in spite of their importance for research and applications. Here we unveil for the first time the MIT in Cr-doped V2O3 with submicron lateral resolution: with decreasing temperature, microscopic domains become metallic and coexist with an insulating background. This explains why the associated PM phase is actually a poor metal. The phase separation can be associated with a thermodynamic instability near the transition. This instability is reduced by pressure which drives a genuine Mott transition to an eventually homogeneous metallic state.
description: Paper plus supplementary material
31891: Day 51 "working from home"
Creators: name: Project, Lockdown2020 and Beyond
Publisher: name: University of Oxford
Year: 2023
Subjects: classificationCode: 479999
subject: Other language, communication and culture not elsewhere classified

description: A typical day starts with a tea or coffee and then I go for a run using the couch to 5K app. After a shower and a change of clothes and a bowl of cereal I then start up my computer and work from home. I keep a calendar next to my monitor so that I know what day it is and know if its the weekend or not. I work remotely, sort through emails and attend meetings in "Teams" and carry on as if I am in my office. I try to break for lunch and sit outside in the sunshine. I try to work until 5pm, shut my work computer down and then use my own device to get involved in the Great British Home Chorus for 30minutes. My evening then involves a combination of attending "Zoom" meetings for various music groups and choirs I attended before we all went online, and watching TV, I tend to watch alot of BBC and Channel 4 programs and am really getting into all of the art and craft stuff thats on. If I have some energy left I will try and practice my violin and flute for half and hour or so before watching more TV and then going to bed. Weekends I tend to do alot of cleaning and lounging around.
Towards prediction of ordered phases in rechargeable battery chemistry via group–subgroup transformation
Creators: name: Ran, Yunbing
name: Zou, Zheyi
name: Liu, Bo
name: Wang, Da
name: Pu, Bowei
name: Mi, Penghui
name: Shi, Wei
name: Li, Yajie
name: He, Bing
name: Lu, Ziheng
name: Lu, Xia
name: Li, Baihai
name: Shi, Siqi
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/639/766/25
/639/301/1034/1035
article

description: Abstract: The electrochemical thermodynamic and kinetic characteristics of rechargeable batteries are critically influenced by the ordering of mobile ions in electrodes or solid electrolytes. However, because of the experimental difficulty of capturing the lighter migration ion coupled with the theoretical limitation of searching for ordered phases in a constrained cell, predicting stable ordered phases involving cell transformations or at extremely dilute concentrations remains challenging. Here, a group-subgroup transformation method based on lattice transformation and Wyckoff-position splitting is employed to predict the ordered ground states. We reproduce the previously reported Li0.75CoO2, Li0.8333CoO2, and Li0.8571CoO2 phases and report a new Li0.875CoO2 ground state. Taking the advantage of Wyckoff-position splitting in reducing the number of configurations, we identify the stablest Li0.0625C6 dilute phase in Li-ion intercalated graphite. We also resolve the Li/La/vacancy ordering in Li3xLa2/3−xTiO3 (0 < x < 0.167), which explains the observed Li-ion diffusion anisotropy. These findings provide important insight towards understanding the rechargeable battery chemistry.
Self-organized adaptation of a simple neural circuit enables complex robot behaviour
Creators: name: Steingrube, Silke
name: Timme, Marc
name: Woergoetter, Florentin
name: Manoonpong, Poramate
Publisher: name: arXiv
Year: 2011
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Artificial Intelligence (cs.AI)
subject: Robotics (cs.RO)
subject: Chaotic Dynamics (nlin.CD)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Controlling sensori-motor systems in higher animals or complex robots is a challenging combinatorial problem, because many sensory signals need to be simultaneously coordinated into a broad behavioural spectrum. To rapidly interact with the environment, this control needs to be fast and adaptive. Current robotic solutions operate with limited autonomy and are mostly restricted to few behavioural patterns. Here we introduce chaos control as a new strategy to generate complex behaviour of an autonomous robot. In the presented system, 18 sensors drive 18 motors via a simple neural control circuit, thereby generating 11 basic behavioural patterns (e.g., orienting, taxis, self-protection, various gaits) and their combinations. The control signal quickly and reversibly adapts to new situations and additionally enables learning and synaptic long-term storage of behaviourally useful motor responses. Thus, such neural control provides a powerful yet simple way to self-organize versatile behaviours in autonomous agents with many degrees of freedom.
description: 16 pages, non-final version, for final see Nature Physics homepage
Exploring issues of identity for adult haematology oncology patients
Creators: name: Stephens, Jennifer Marie Lior
Publisher: name: University of British Columbia
Year: 2018

description: Caring for adult haematology cancer patients can be challenging, and the difference in experience between this cancer subgroup and solid tumour cancers is only recently becoming a topic of investigation as researchers seek to identify and understand fundamental biological and psychological dissimilarities. The issue of identity is one that is of intense consequence for many cancer patients as they move from one state of being to another. This qualitative study was undertaken to generate knowledge about this important concern in a way that would ultimately inform an understanding of how to improve the patient experience of care with regards to identity concerns. Interpretive description served as the methodological framework which guided a data collection and analysis strategy composed of five consecutive layers. Secondary research included a critical integrative literature review, a historical inquiry, and a secondary analysis of a pre-existing qualitative database. Primary research was composed of semi-structured interviews undertaken with a haematology oncology patient cohort as well as semi-structured interviews with experienced oncology clinicians. Findings revealed that adult haematology oncology patients co-create and enact new identities that are increasingly aligned with a distinct experience defined specifically by their cancer subtype. Pre-existing identity labels and associated behaviours and expectations generally were viewed by patients as inadequate to fully describe and inform their experience of having a haematological cancer. Knowledge-gathering, linking with others who had similarly unique diagnoses down to a genetic level, and exploring the abstract cellular nature of their disease were just some of the themes that addressed ways these patients engaged with the highly complex and embodied construct known as identity. Several implications for clinical practice resulted from this study and include the importance of recognizing identity as simultaneously a physiological and psycho-social concern that will mean different things to different people at different times in the course of their disease. Implications for further research include advocating for theoretical and substantive knowledge development around identity constructs to generate further understanding of the deeply-rooted, textured relationship between identity and overall well-being.
Semiclassical theory of spin-orbit interaction in the extended phase space
Creators: name: Pletyukhov, Mikhail
name: Zaitsev, Oleg
Publisher: name: Universität Regensburg
Year: 2003
Subjects: subject: 530 Physik

description: We consider the semiclassical theory in a joint phase space of spin and orbital degrees of freedom. The method is developed from the path integral using the spin-coherent-state representation, and yields the trace formula for the density of states. We discuss the limits of weak and strong spin–orbit coupling and relate the present theory to the earlier approaches.
Mitigating losses: how scientific organisations can help address the impact of the COVID-19 pandemic on early-career researchers.
Creators: name: López-Vergès, Sandra
name: Urbani, Bernardo
name: Fernández Rivas, David
name: Kaur-Ghumaan, Sandeep
name: Coussens, Anna K
name: Moronta-Barrios, Felix
name: Bhattarai, Suraj
name: Niamir, Leila
name: Siciliano, Velia
name: Molnar, Andreea
name: Weltman, Amanda
name: Dhimal, Meghnath
name: Arya, Shalini S
name: Cloete, Karen J
name: Awan, Almas Taj
name: Kohler, Stefan
name: Sharma, Chandra Shekhar
name: Rios Rojas, Clarissa
name: Shimpuku, Yoko
name: Ganle, John
name: Matin, Maryam M
name: Nzweundji, Justine G
name: Badre, Abdeslam
name: Carmona-Mora, Paulina
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Health Humanities
Science, Technology And Society

description: Scientific collaborations among nations to address common problems and to build international partnerships as part of science diplomacy is a well-established notion. The international flow of people and ideas has played an important role in the advancement of the 'Sciences' and the current pandemic scenario has drawn attention towards the genuine need for a stronger role of science diplomacy, science advice and science communication. In dealing with the COVID-19 pandemic, visible interactions across science, policy, science communication to the public and diplomacy worldwide have promptly emerged. These interactions have benefited primarily the disciplines of knowledge that are directly informing the pandemic response, while other scientific fields have been relegated. The effects of the COVID-19 pandemic on scientists of all disciplines and from all world regions are discussed here, with a focus on early-career researchers (ECRs), as a vulnerable population in the research system. Young academies and ECR-driven organisations could suggest ECR-powered solutions and actions that could have the potential to mitigate these effects on ECRs working on disciplines not related to the pandemic response. In relation with governments and other scientific organisations, they can have an impact on strengthening and creating fairer scientific systems for ECRs at the national, regional, and global level.
Water in most important towns of the Czech Republic
Creators: name: Dušek, Radek
name: Popelková, Renata
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: An analysis of surface water presence of one hundred most important towns of the Czech Republic has been conducted with respect to their proportion to town area. The results of the analysis, which was performed on the basis of data from specialised water management database, were visualised in a poster clearly showing ‘blue areas’ in given towns. In relation to the visualisation purpose, which was the comparison of towns, the towns were presented so that their area was identical. The order of towns in the poster was established in accordance with the representation of blue areas. As supplementary information, the total area of blue areas per capita was displayed in visual form. The poster is accompanied by a map showing the location of the towns within the Czech Republic.
Tolerant pattern recognition: evidence from phonotactic responses in the cricket Gryllus bimaculatus (de Geer).
Creators: name: Bent, Adam M
name: Hedwig, Berthold
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Gryllus bimaculatus
Acoustic Communication
Calling song
Phonotaxis
Oddball Paradigm
Tolerant Pattern Recognition

description: When the amplitude modulation of species-specific acoustic signals is distorted in the transmission channel, signals become difficult to recognize by the receiver. Tolerant auditory pattern recognition systems, which after having perceived the correct species-specific signal transiently broaden their acceptance of signals, would be advantageous for animals as an adaptation to the constraints of the environment. Using a well-studied cricket species, Gryllus bimaculatus, we analysed tolerance in auditory steering responses to 'Odd' chirps, mimicking a signal distorted by the transmission channel, and control 'Silent' chirps by employing a fine-scale open-loop trackball system. Odd chirps on their own did not elicit a phonotactic response. However, when inserted into a calling song pattern with attractive Normal chirps, the females' phonotactic response toward these patterns was significantly larger than to patterns with Silent chirps. Moreover, females actively steered toward Odd chirps when these were presented within a sequence of attractive chirps. Our results suggest that crickets employ a tolerant pattern recognition system that, once activated, transiently allows responses to distorted sound patterns, as long as sufficient natural chirps are present. As pattern recognition modulates how crickets process non-attractive acoustic signals, the finding is also relevant for the interpretation of two-choice behavioural experiments.
After Virtue: A Study in Moral Theory, Third Edition
Creators: name: MacIntyre, Alasdair
Publisher: name: University of Notre Dame
Year: 2023

description: When _After Virtue_ first appeared in 1981, it was recognized as a significant and potentially controversial critique of contemporary moral philosophy. Newsweek called it a stunning new study of ethics by one of the foremost moral philosophers in the English-speaking world.' Since that time, the book has been translated into more than fifteen foreign languages and has sold over one hundred thousand copies. Now, twenty-five years later, the University of Notre Dame Press is pleased to release the third edition of _After Virtue_, which includes a new prologue '_After Virtue_ after a Quarter of a Century.'\u000a\u000aIn this classic work, Alasdair MacIntyre examines the historical and conceptual roots of the idea of virtue, diagnoses the reasons for its absence in personal and public life, and offers a tentative proposal for its recovery. While the individual chapters are wide-ranging, once pieced together they comprise a penetrating and focused argument about the price of modernity. In the Third Edition prologue, MacIntyre revisits the central theses of the book and concludes that although he has learned a great deal and has supplemented and refined his theses and arguments in other works, he has 'as yet found no reason for abandoning the major contentions of this book. While he recognizes that his conception of human beings as virtuous or vicious needed not only a metaphysical but also a biological grounding, ultimately he remains 'committed to the thesis that it is only from the standpoint of a very different tradition, one whose beliefs and presuppositions were articulated in their classical form by Aristotle, that we can understand both the genesis and the predicament of moral modernity.'\u000a\u000a\u00A9 University of Notre Dame\u000a\u000aCopyright for most content is held by The University of Notre Dame. Reproduction of all or any portion of content constitutes a violation of copyright. You must obtain permission from The Copyright Clearance Center or The University of Notre Dame Press in order to reprint (or adapt) content.\u000a\u000ap: (574) 631-6346 \ e: undpress@nd\.edu \ website: copyright\.com'
Compact HI clouds from the GALFA-HI survey
Creators: name: Begum, Ayesha
name: Stanimirovic, Snezana
name: Peek, Joshua E.
name: Ballering, Nicholas P.
name: Heiles, Carl
name: Douglas, Kevin A.
name: Putman, Mary
name: Gibson, Steven J.
name: Grcevich, Jana
name: Korpela, Eric J.
name: Lee, Min-Young
name: Saul, Destry
name: Gallagher, John S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The Galactic Arecibo L-band Feed Array HI (GALFA-HI) survey is mapping the entire Arecibo sky at 21-cm, over a velocity range of -700 to +700 km/s (LSR), at a velocity resolution of 0.18 km/s and a spatial resolution of 3.5 arcmin. The unprecedented resolution and sensitivity of the GALFA-HI survey have resulted in the detection of numerous isolated, very compact HI clouds at low Galactic velocities, which are distinctly separated from the HI disk emission. In the limited area of ~4600 deg$^2$ surveyed so far, we have detected 96 of such compact clouds. The detected clouds are cold with a median T$_{k,max}$ (the kinetic temperature in the case in which there is no non-thermal broadening) of 300 K. Moreover, these clouds are quite compact and faint, with median values of 5 arcmin in angular size, 0.75 K in peak brightness temperature, and $5 \times 10^{18}$ cm$^{-2}$ in HI column density. Most of the clouds deviate from Galactic rotation at the 20-30 km/s level, and a significant fraction show evidence for a multiphase medium and velocity gradients. No counterparts for these clouds were found in other wavebands. From the modeling of spatial and velocity distributions of the whole compact cloud population, we find that the bulk of the compact clouds are related to the Galactic disk, and their distances are likely to be in the range of 0.1 to a few kpc. We discuss various possible scenarios for the formation and maintenance of this cloud population and its significance for Galactic ISM studies.
description: Accepted for publication in the Astrophysical Journal
Flooding, channel dynamics and transverse infrastructure: a challenge for Middle Ebro river management
Creators: name: Horacio, Jesús
name: Ollero, Alfredo
name: Noguera, Iván
name: Fernández-Pasquier, Víctor
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: This study documents the impacts of engineering works on flood risk and channel dynamics of the maximum geomorphic flow reach of the Middle Ebro River (Spain) over the last ninety years. The map reveals how the construction of transversal transport lines and their ineffective design and maintenance has contributed to an elevated risk of flooding and channel avulsion at this location. In addition, the development of flood protection structures has restricted the natural dynamics of the river. These modifications have restricted the passage of flood waters, ultimately increasing flood hazards, by changing the area and depth of inundation and extending the flood hydrograph. The map allows for the interpretation of key processes, forecasting of flood hazards, and the evaluation of possible mitigating actions. These findings reconfirm that reducing space for the mobility of a river is not a good management solution and further aggravates the current situation.
Defining the intrinsic AGN infrared spectral energy distribution and measuring its contribution to the infrared output of composite galaxies
Creators: name: Mullaney, J. R.
name: Alexander, D. M.
name: Goulding, A. D.
name: Hickox, Ryan C.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We use infrared spectroscopy and photometry to empirically define the intrinsic, thermal infrared spectral energy distribution (i.e., 6-100 um SED) of typical active galactic nuclei (i.e., 2-10 keV luminosity, Lx=10^{42}-10^{44} ergs/s AGNs). On average, the infrared SED of typical AGNs is best described as a broken power-law at <40 um that falls steeply at >40um (i.e., at far-infrared wavelengths). Despite this fall-off at long wavelengths, at least 3 of the 11 AGNs in our sample have observed SEDs that are AGN-dominated even at 60 um, demonstrating the importance of accounting for possible AGN contribution even at far-infrared wavelengths. Our results also suggest that the average intrinsic AGN 6-100 um SED gets bluer with increasing X-ray luminosity, a trend seen both within our sample and also when we compare against the intrinsic SEDs of more luminous quasars (i.e., Lx>10^{44} ergs/s). We compare our intrinsic AGN SEDs with predictions from dusty torus models and find they are more closely matched by clumpy, rather than continuous, torus models. Next, we use our intrinsic AGN SEDs to define a set of correction factors to convert either monochromatic infrared or X-ray luminosities into total intrinsic AGN infrared (i.e., 8-1000 um) luminosities. Finally, we outline a procedure that uses our newly defined intrinsic AGN infrared SEDs, in conjunction with a selection of host-galaxy templates, to fit the infrared photometry of composite galaxies and measure the AGN contribution to their total infrared output. We verify the accuracy of our SED fitting procedure by comparing our results to two independent measures of AGN contribution. Our SED fitting procedure opens up the possibility of measuring the intrinsic AGN luminosities of large numbers of galaxies with well-sampled infrared data (e.g., IRAS, ISO, Spitzer and Herschel).
description: Main article: 17 pages, appendix: 13 pages; 13 figures; accepted for publication in MNRAS
Extracellular vesicle miRNAs are regulators of lung adenocarcinoma tumor progression and are important tumor-stromal communicators
Creators: name: Lawson, James
Publisher: name: University of British Columbia
Year: 2018

description: Lung adenocarcinoma (LAC) is the most common subtype of non-small cell lung cancer and is the leading cause of cancer death worldwide. Five-year survival rates of LAC remain dismally low at ~17%, due to the late stage of diagnosis. MicroRNAs (miRNAs) are small RNAs 17-22 nucleotides long and are stable within the serum and when present within extracellular vesicles (EVs), additionally EV miRNAs contribute to tumor-stromal communication. Determining non-invasive novel biomarkers for early disease detection and understanding EV miRNA tumor-stromal communication may aid in improving overall survival. In this thesis, I identify miRNAs that are differentially detected within the serum of patients with LAC using miRNA profiling of patient serum samples and demographically matched controls. I additionally characterize the function of LAC secreted miRNA within EVs when entering normal fibroblast and endothelial cells. My hypotheses are that miRNAs within the serum of LAC patients will show a unique signature that will be distinguishable from non-cancer high risk individuals, and that miRNAs selectively released from LAC cells within EVs will promote tumorigenesis in endothelial cells through stimulating angiogenesis and in fibroblasts through promoting the cancer associated fibroblast phenotype. A unique signature of miRNAs within the serum of LAC patients is found and miRNAs within patient serum is dependent on sex. Several miRNAs within LAC EVs are then functionally characterized in the role they play when signaling to normal stromal cells. Together, this thesis provides a comprehensive analysis of LAC miRNAs and the roles they play as biomarkers within the serum and as tumor-stromal signals when within EVs.
New work and old ways : a sermon preached at the opening of the monastery and College of St. Benedict, at Fort Augustus, on August 26th, 1880. By the Right Rev. Bishop Hedley.
Creators: name: Hedley, John Cuthbert, 1837-1915.
Publisher: name: University of Notre Dame
Year: 2023

description:
 Text: Isaias xliii, 16, 19,
Changes in forest cover in Sierra Nevada, Mexico, 1994–2015
Creators: name: López-García, José
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Sierra Nevada, 153,437 ha, has the second and third highest mountains in Mexico and the most conserved coniferous forests of central Mexico. It comprises the Los Volcanes Biosphere Reserve, designated by UNESCO in 2010. A map was produced at 1:100,000 scale. Recent changes in forest cover were identified by visual interpretation of orthophotographs from 1994 and Spot 7 images from 2015. Changes were detected in forest cover density (closed, semi-closed, semi-open, open or deforested), together with a non-forest category that includes other land uses. Over the 21 years, 25% of the forest had undergone change: 14% recovery and 11% disturbance. Recovery outweighed disturbance in the Protected Areas, with possible factors being payment for environmental services, periodic reforestation and fire control. Outside this protected area, improvement outweighed degradation, mainly because of forestry programs. Overall in the Sierra Nevada, the trend appears to be forest recovery.
Parity nonconservation in deuteron photoreactions
Creators: name: Partanen, T. M.
name: Niskanen, J. A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We calculate the asymmetries in parity nonconserving deuteron photodisintegration due to circularly polarized photons gamma+d to n+p with the photon laboratory energy ranging from the threshold up to 10 MeV and the radiative capture of thermal polarized neutrons by protons n+p to gamma+d. We use the leading order electromagnetic Hamiltonian neglecting the smaller nuclear exchange currents. Comparative calculations are done by using the Reid93 and Argonne v18 potentials for the strong interaction and the DDH and FCDH "best" values for the weak couplings in a weak one-meson exchange potential. A weak NDelta transition potential is used to incorporate also the Delta(1232)-isobar excitation in the coupled-channels formalism.
description: 14 pages, 13 figures (18 eps files), LaTeX2e
title: Φραιζάρισμα 2.5 αξόνων με τη βοήθεια λογισμικού CAD/CAM
title: 2 ½ Axes milling by means of a CAD/CAM software
Creators: name: Θεοχαρης Ευαγγελος
Publisher: name: Technical University of Crete
Year: 2023

description: Στην παρούσα εργασία θα πραγματοποιηθεί ανάλυση της διαδικασίας ορισμού τεμαχίων στο λογισμικό Autodesk Inventor CAM με απώτερο σκοπό την εξαγωγή του κώδικα καθοδήγησης (G-code). Θα παρουσιαστούν όλα τα βήματα που είναι αναγκαία για να φτάσει ο χρήστης στο τελικό στάδιο της εξαγωγής του κώδικα, τα οποία ενδεικτικά αφορούν:
-την αρχικοποίηση του τεμαχίου και της CNC μηχανής,
-την κατάλληλη επιλογή και παραμετροποίηση κατεργασιών – στρατηγικών φραιζαρίσματος και τέλος,
-τις αναγκαίες ενέργειες που πρέπει να γίνουν ώστε να μεταφραστούν κατάλληλα οι διαδρομές του εργαλείου σε γλώσσα που καταλαβαίνει η μηχανή.
Τελικά, θα δοθούν οδηγίες προσομοίωσης των διαδρομών του εργαλείου αλλά και μέθοδος παρουσίασης τους σε ηλεκτρονικό φύλλο χαρτιού.
Higgs Properties in the Fourth Generation MSSM: Boosted Signals Over the 3G Plan
Creators: name: Cotta, R. C.
name: Hewett, J. L.
name: Ismail, A.
name: Le, M. -P.
name: Rizzo, T. G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The generalization of the MSSM to the case of four chiral fermion generations (4GMSSM) can lead to significant changes in the phenomenology of the otherwise familiar Higgs sector. In most of the 3GMSSM parameter space, the lighter CP-even $h$ is $\sim 115-125$ GeV and mostly Standard Model-like while $H,A,H^\pm$ are all relatively heavy. Furthermore, the ratio of Higgs vevs, $\tan β$, is relatively unconstrained. In contrast to this, in the 4GMSSM, heavy fourth generation fermion loops drive the masses of $h,H,H^\pm$ to large values while the CP-odd boson, $A$, can remain relatively light and $\tan β$ is restricted to the range $1/2 \lsim \tan β\lsim 2$ due to perturbativity requirements on Yukawa couplings. We explore this scenario in some detail, concentrating on the collider signatures of the light CP-odd Higgs at both the Tevatron and LHC. We find that while $gg \to A$ may lead to a potential signal in the $τ^+τ^-$ channel at the LHC, $A$ may first be observed in the $γγ$ channel due to a highly loop-enhanced cross section that can be more than an order of magnitude greater than that of a SM Higgs for $A$ masses of $\sim 115-120$ and $\tanβ<1$. We find that the CP-even states $h,H$ are highly mixed and can have atypical branching fractions. Precision electroweak constraints, particularly for the light $A$ parameter space region, are examined in detail.
description: 20 pages, 7 figures; typos fixed, refs added
Instruction on the extension of the faculty to distribute Holy Communion under both kinds. Sacred Congregation for Divine Worship.
Creators: name: Catholic Church.Congregatio Pro Cultu Divino.
Publisher: name: University of Notre Dame
Year: 2023

description:
 Cover title.
 Translation of: Instructio de cultu mysterii eucharistici, Eucharisticum mysterium, 25 maii 1967, n. 32, ratified by Pope Paul VI and promulgated on June 29, 1970.--Cf. page 3.
 June 29, 1970.
Excess AGN Activity in the z=2.30 Protocluster in HS 1700+64
Creators: name: Digby-North, J. A.
name: Nandra, K.
name: Laird, E. S.
name: Steidel, C. C.
name: Georgakakis, A.
name: Bogosavljević, M.
name: Erb, D. K.
name: Shapley, A. E.
name: Reddy, N. A.
name: Aird, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the results of spectroscopic, narrow-band and X-ray observations of a z=2.30 protocluster in the field of the QSO HS 1700+643. Using a sample of BX/MD galaxies, which are selected to be at z~2.2-2.7 by their rest-frame ultraviolet colours, we find that there are 5 protocluster AGN which have been identified by characteristic emission-lines in their optical/near-IR spectra; this represents an enhancement over the field significant at ~98.5 per cent confidence. Using a ~200 ks Chandra/ACIS-I observation of this field we detect a total of 161 X-ray point sources to a Poissonian false-probability limit of 4x10^{-6} and identify 8 of these with BX/MD galaxies. Two of these are spectroscopically confirmed protocluster members and are also classified as emission-line AGN. When compared to a similarly selected field sample the analysis indicates this is also evidence for an enhancement of X-ray selected BX/MD AGN over the field, significant at ~99 per cent confidence. Deep Lya narrow-band imaging reveals that a total of 4/123 Lya emitters (LAEs) are found to be associated with X-ray sources, with two of these confirmed protocluster members and one highly likely member. We do not find a significant enhancement of AGN activity in this LAE sample over that of the field (result significant at only 87 per cent confidence). The X-ray emitting AGN fractions for the BX/MD and LAE samples are found to be 6.9_{-4.4}^{+9.2} and 2.9_{-1.6}^{+2.9} per cent, respectively, for protocluster AGN with L_{2-10 keV}>4.6x10^{43} erg s^{-1} at z=2.30. These findings are similar to results from the z=3.09 protocluster in the SSA 22 field found by Lehmer et al. (2009), in that both suggest AGN activity is favoured in dense environments at z>2.
description: 8 pages, 2 figures. Accepted for publication in MNRAS.
Andreev magnetotransport in low-dimensional proximity structures: Spin-dependent conductance enhancement
Creators: name: Tkachov, Grygoriy
name: Richter, Klaus
Publisher: name: Universität Regensburg
Year: 2005
Subjects: subject: 530 Physik
subject: 74.45.1c
subject: 73.23.Ad
subject: 72.25.Dc

description: We study the excess conductance due to the superconducting proximity effect in a ballistic two-dimensional electron system subject to an in- plane magnetic field. We show that under certain conditions the interplay of the Zeeman spin splitting and the effect of a screening supercurrent gives rise to a spin-selective Andreev enhancement of the conductance and anomalies in its voltage, temperature and magnetic field characteristics. The magnetic-field influence on Andreev reflection is discussed in the context of using superconducting hybrid junctions for spin detection.
Correlations, Plasmarons, and Quantum Spectral Function in Bilayer Graphene
Creators: name: Sensarma, Rajdeep
name: Hwang, E. H.
name: Sarma, S. Das
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We theoretically study the many-body effects of electron electron interaction on the single particle spectral function of doped bilayer graphene. Using random phase approximation, we calculate the real and imaginary part of the self-energy and hence the spectral function. The spectral function near the Fermi surface shows the usual quasiparticle peak, establishing doped bilayer graphene, in contrast to the unstable neutral system, to be a Fermi liquid. Away from the Fermi surface, an additional broad plasmaron peak is visible in the spectral function. From the low energy behaviour of the self-energy we calculate the quasiparticle residue and the effective mass of the quasiparticles as a function of carrier density. We present results for both the on-shell and the off-shell approximation for the quasiparticle renormalization.
description: 5 pages, 3 figures
High-spatial-resolution imaging of thermal emission from debris disks
Creators: name: Moerchen, Margaret
name: Telesco, Charles
name: Packham, Christopher
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We have obtained sub-arcsec mid-IR images of a sample of debris disks within 100 pc. For our sample of nineteen A-type debris disk candidates chosen for their IR excess, we have resolved, for the first time, five sources plus the previously resolved disk around HD 141569. Two other sources in our sample have been ruled out as debris disks since the time of sample selection. Three of the six resolved sources have inferred radii of 1-4 AU (HD 38678, HD 71155, and HD 181869), and one source has an inferred radius ~10-30 AU (HD 141569). Among the resolved sources with detections of excess IR emission, HD 71155 appears to be comparable in size (r~2 AU) to the solar system's asteroid belt, thus joining Zeta Lep (HD 38678, reported previously) to comprise the only two resolved sources of that class. Two additional sources (HD 95418 and HD 139006) show spatial extent that implies disk radii of ~1-3 AU, although the excess IR fluxes are not formally detected with better than 2-sigma significance. For the unresolved sources, the upper limits on the maximum radii of mid-IR disk emission are in the range ~1-20 AU, four of which are comparable in radius to the asteroid belt. We have compared the global color temperatures of the dust to that expected for the dust in radiative equilibrium at the distances corresponding to the observed sizes or limits on the sizes. In most cases, the temperatures estimated via these two methods are comparable, and therefore, we see a generally consistent picture of the inferred morphology and the global mid-IR emission. Finally, while our sample size is not statistically significant, we notice that the older sources (>200 Myr) host much warmer dust (T > 400 K) than younger sources (in the 10s of Myr).
description: 46 pages, 12 figures