cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Interpregnancy weight change as a potential risk factor for large-for-gestational-age infants: the Japan Environment and Children’s Study
Creators: name: Shinohara, Satoshi
name: Horiuchi, Sayaka
name: Shinohara, Ryoji
name: Otawa, Sanae
name: Kushima, Megumi
name: Miyake, Kunio
name: Yui, Hideki
name: Kojima, Reiji
name: Ooka, Tadao
name: Akiyama, Yuka
name: Yokomichi, Hiroshi
name: Yamagata, Zentaro
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: This study aimed to estimate the impact of interpregnancy weight change from the first to the second pregnancy on the risk of infants being large for gestational age (LGA). This nationwide prospective birth cohort analysis included 3245 women who delivered their first two live singletons between 2011 and 2014. Interpregnancy weight change was calculated as the difference between the prepregnancy body mass index (BMI) of the first and second pregnancies. LGA infants were compared among three interpregnancy weight change groups: weight loss (a BMI loss >1 unit), weight gain (a BMI gain >1 unit), and stable weight (BMI maintained within − 1 to <1 unit). Interpregnancy weight change was assessed in mothers with a BMI <25 and ≥25 kg/m2, and adjusted odds ratios (ORs) were calculated for LGA infants by multiple logistic regression. The incidence of LGA infants was 8.6% (279 out of 3245). Compared with the stable weight group, interpregnancy weight gain was associated with an increased risk of infants being LGA (adjusted OR: 1.69, 95% confidence interval: 1.21–2.36) in the normal BMI (<25 kg/m2) group. In contrast, in the overweight/obese BMI (≥25 kg/m2) group, interpregnancy BMI was not a significant risk factor for LGA infants. Accurate risk stratification using interpregnancy BMI could assist the clinical management of women with a normal BMI who are at risk of delivering LGA infants.
Re-housing Taxidermy-mounted Bird and Mammal Specimens at the Michigan State University Museum
Creators: name: Abraczinskas, Laura
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on Re-housing Taxidermy-mounted Bird and Mammal Specimens at the Michigan State University Museum by Collections Manager Laura Abraczinskas of Collections Manager Michigan State University Museum East Lansing United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Investigations on the effect of metal transfer modes on fume generation rate during gas metal arc welding of austenitic stainless steel
Creators: name: Kasi, Srinivasan
name: Visvalingam, Balasubramanian
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Space Science
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: This paper presents the characterisation results of the welding fumes generated during welding of austenitic stainless steel plates. The variants of gas metal arc welding (GMAW) process such as pulsed and surface tension transfer modes (STT) were used. Fumes were collected for five levels of wire feed speed and five levels of voltage. Investigation reveals that GMAW with STT mode reduced the Fume Formation Rate (FFR) above 50% when compared with constant current mode and above 38% when compared with pulsed current mode. Scanning Electron Microscopy analysis revealed three different types of particles like agglomerated, individual spherical and irregular particles. The fumes consists predominately of particle agglomerates smaller than 1 μm. Constant current mode produces smallest particle size than particles from other two variants and STT mode produces largest average particle size. XEDS analysis of chemical composition of fume particles obtained from all the three variants of GMAW process show significant difference on elements like Cr, Mn, Fe and Ni. Spot XEDS analysis of the selected fume particles shows considerable reduction in chemical composition when compared with bulk fume analysis.
Genes That Mediate Starch Metabolism in Developing and Germinated Barley Grain
Creators: name: HM Collins
name: NS Betts
name: C Dockter
name: Berkowitz, Oliver
name: I Braumann
name: JA Cuesta-Seijo
name: B Skadhauge
name: Whelan, James
name: V Bulone
name: GB Fincher
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Starch is synthesized in the endosperm of developing barley grain, where it functions as the primary source of stored carbohydrate. In germinated grain these starch reserves are hydrolyzed to small oligosaccharides and glucose, which are transported to the embryo to support the growth of the developing seedling. Some of the mobilized glucose is transiently stored as starch in the scutellum of germinated grain. These processes are crucial for early seedling vigor, which is a key determinant of crop productivity and global food security. Several starch synthases (SS), starch-branching enzymes (SBEs), and starch debranching enzymes (isoamylases, ISA), together with a limit dextrinase (LD), have been implicated in starch synthesis from nucleotide-sugar precursors. Starch synthesis occurs both in the developing endosperm and in the scutellum of germinated grain. For the complete depolymerization of starch to glucose, α-amylase (Amy), β-amylase (Bmy), isoamylase (ISA), limit dextrinase (LD), and α-glucosidase (AGL) are required. Most of these enzymes are encoded by gene families of up to 10 or more members. Here RNA-seq transcription data from isolated tissues of intact developing and germinated barley grain have allowed us to identify the most important, specific gene family members for each of these processes in vivo and, at the same time, we have defined in detail the spatio-temporal coordination of gene expression in different tissues of the grain. A transcript dataset for 81,280 genes is publicly available as a resource for investigations into other cellular and biochemical processes that occur in the developing grain from 6 days after pollination.
A survey of consensus algorithms in public blockchain systems for crypto-currencies
Creators: name: Ferdous, MS
name: Chowdhury, Mohammad Jabed Morshed
name: Hoque, MA
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: In recent years, crypto-currencies (a form of decentralised digital currencies) have been quite popular as an alternative form of payments. They are underpinned by a breakthrough technology called Blockchain which extensively use a number of cryptographic mechanisms and other advanced techniques from the domain of distributed computing. This blockchain technology has received unparalleled attention from academia, industry, and governments worldwide and is considered to have the potential to disrupt several application domains, other than currencies, touching all spheres of our lives. The sky-rocket anticipation of its potential has caused a wide-scale exploration of its usage in different application domains. This has resulted in a plethora of blockchain systems for various purposes. However, many of these blockchain systems suffer from serious shortcomings related to their performance and security, which need to be addressed before any wide-scale adoption can be achieved. A crucial component of any blockchain system is its underlying consensus algorithm, which determines its performance and security in many ways. Therefore, to address the limitations of different blockchain systems, several existing as well novel consensus algorithms have been introduced. A systematic analysis of these algorithms will help to understand how and why any particular blockchain performs the way it functions. Towards this aim, there are a number of existing works that have surveyed and reviewed a number of consensus algorithms. However, all these works have some major shortcomings. For example, the factors upon which the consensus algorithms have been analysed are not comprehensive. Importantly, a wide range of consensus algorithms utilised in public blockchain systems supporting mainly crypto-currencies have different variants. Such variants and their internal mechanisms utilised in many existing crypto-currencies have not been considered at all. This article fills these gaps by analysing a wide range of consensus algorithms leveraged in different public blockchain systems using a comprehensive taxonomy of properties. We have also analysed more than a hundred top crypto-currencies belonging to different categories of consensus algorithms to understand their properties and implicate different trends in these crypto-currencies. Finally, we have presented a decision tree of the reviewed algorithms to be used as a tool to test the suitability of consensus algorithms for a particular application under different criteria.
The 2019/2020 mega-fires exposed Australian ecosystems to an unprecedented extent of high-severity fire
Creators: name: Collins, Luke
name: RA Bradstock
name: H Clarke
name: Clarke, Michael
name: RH Nolan
name: TD Penman
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Extreme fire seasons characterised by very large 'mega-fires' have demonstrably increased area burnt across forested regions globally. However, the effect of extreme fire seasons on fire severity, a measure of fire impacts on ecosystems, remains unclear. Very large wildfires burnt an unprecedented area of temperate forest, woodland and shrubland across south-eastern Australia in 2019/2020, providing an opportunity to examine the impact of extreme fires on fire severity patterns. We developed an atlas of wildfire severity across south-eastern Australia between 1988 and 2020 to test (a) whether the 2019/2020 fire season was more severe than previous fire seasons, and (b) if the proportion of high-severity fire within the burn extent (HSp) increases with wildfire size and annual area burnt. We demonstrate that the 2019/2020 wildfires in south-eastern Australia were generally greater in extent but not proportionally more severe than previous fires, owing to constant scaling between HSp and annual fire extent across the dominant dry-forest communities. However, HSp did increase with increasing annual fire extent across wet-forests and the less-common rainforest and woodland communities. The absolute area of high-severity fire in 2019/2020 (∼1.8 M ha) was larger than previously seen, accounting for ∼44% of the area burnt by high-severity fire over the past 33 years. Our results demonstrate that extreme fire seasons are a rare but defining feature of fire regimes across forested regions, owing to the disproportionate influence of mega-fires on area burnt.
Technical Report on Neural Language Models and Few-Shot Learning for Systematic Requirements Processing in MDSE
Creators: name: Bertram, Vincent
name: Boß, Miriam
name: Kusmenko, Evgeny
name: Nachmann, Imke Helene
name: Rumpe, Bernhard
name: Trotta, Danilo
name: Wachtmeister, Louis
Publisher: name: RWTH Aachen University
Year: 2022

description: 24 Seiten (2022). doi:10.48550/arXiv.2211.09084
Additional file 3 of Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial
Creators: name: Nakamura, Yoshihiko
name: Hatomoto, Hiroki
name: Yamasaki, Shintaro
name: Yamauchi, Kazuya
name: Kiyomi, Fumiaki
name: Hoshino, Kota
name: Kawano, Yasumasa
name: Nakano, Takafumi
name: Hasegawa, Takehiro
name: Ishikura, Hiroyasu
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 3. Number of serious adverse events.
title: Prevalence of Sexualised Violence
title: Youth Sexuality 9th Iteration. BZgA Fact Sheet
titleType: Subtitle
Creators: name: Erkens, Christiane
name: Scharmanski, Sara
name: Hessling, Angelika
name: Federal Centre For Health Education (BZgA)
Publisher: name: Federal Centre for Health Education (BZgA)
Year: 2021
Subjects: subject: 10000 Social Sciences
subject: adolescence
subject: communication
subject: prevention
subject: sexual abuse
subject: reproductive health
subject: sexual health
subject: reproduktive Gesundheit
subject: sexuelle Gesundheit
subject: Adoleszenz
subject: Prävention
subject: sexueller Missbrauch
subject: sexual offences
subject: sexuelle Gewalt

description: This fact sheet presents, which experiences adolescents and young adults in Germany have had with non-physical and physical sexualised violence.
description: Fact Sheet Sexuality Education, Contraception and Family Planning
description: Face-to-face interview: CAPI/CAMI
description: Self-administered questionnaire: Computer-assisted (CASI)
Detecting and mitigating mode-collapse for flow-based sampling of lattice field theories
Creators: name: Nicoli, Kim A.
name: Anders, Christopher J.
name: Hartung, Tobias
name: Jansen, Karl
name: Kessel, Pan
name: Nakajima, Shinichi
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2023
Subjects: subject: 530
subject: Monte Carlo: Markov chain
subject: flow
subject: tunneling
subject: lattice field theory
subject: lattice
subject: U(1)
subject: SU(N)
subject: statistical analysis
subject: energy: density
subject: collapse
subject: partition function
subject: spontaneous symmetry breaking
subject: thermodynamical
subject: free energy

description: We study the consequences of mode-collapse of normalizing flows in the context of lattice field theory. Normalizing flows allow for independent sampling. For this reason, it is hoped that they can avoid the tunneling problem of local-update Markov Chain Monte Carlo algorithms for multimodal distributions. In this work, we first point out that the tunneling problem is also present for normalizing flows but is shifted from the sampling to the algorithm’s training phase. Specifically, normalizing flows often suffer from mode-collapse for which the training process assigns vanishingly low probability mass to relevant modes of the physical distribution. This may result in a significant bias when the flow is used as a sampler in a Markov-Chain or with importance sampling. We propose a metric to quantify the degree of mode-collapse and derive a bound on the resulting bias. Furthermore, we propose various mitigation strategies in particular in the context of estimating thermodynamic observables, such as the free energy.
Advancements in multi-omics for nutraceutical enhancement and traits improvement in buckwheat
Creators: name: Song, Yingjie
name: Long, Chunlin
name: Wang, Ying
name: An, Yuxing
name: Lu, Yinglin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Buckwheat (Fagopyrum spp.) is a typical pseudocereal, valued for its extensive nutraceutical potential as well as its centuries-old cultivation. Tartary buckwheat and common buckwheat have been used globally and become well-known nutritious foods due to their high quantities of: proteins, flavonoids, and minerals. Moreover, its increasing demand makes it critical to improve nutraceutical, traits and yield. In this review, bioactive compounds accumulated in buckwheat were comprehensively evaluated according to their chemical structure, properties, and physiological function. Biosynthetic pathways of flavonoids, phenolic acids, and fagopyrin were methodically summarized, with the regulation of flavonoid biosynthesis. Although there are classic synthesis pathways presented in the previous research, the metabolic flow of how these certain compounds are being synthesized in buckwheat still remains uncovered. The functional genes involved in the biosynthesis of flavonols, stress response, and plant development were identified based on multi-omics research. Furthermore, it delves into the applications of multi-omics in improving buckwheat’s agronomic traits, including: yield, nutritional content, stress resilience, and bioactive compounds biosynthesis. While pangenomics combined with other omics to mine elite genes, the regulatory network and mechanism of specific agronomic traits and biosynthetic of bioactive components, and developing a more efficient genetic transformation system for genetic engineering require further investigation for the execution of breeding designs aimed at enhancing desirable traits in buckwheat. This critical review will provide a comprehensive understanding of multi-omics for nutraceutical enhancement and traits improvement in buckwheat. Buckwheat (Fagopyrum spp.) is considered as promising and sustainable nutrient crop for abundant flavonoids, phenolic acids and fagopyrum production with impressive biosynthetic capacity. The chemical structure, properties, physiological function, and biosynthesis pathways of these bioactive components are summarized. The comprehensive information of multi-omics including genome, transcriptome, proteome, and metabolism for buckwheat nutraceutical traits improvement has been concluded. The pangenomics combined with other omics to mine elite genes, and regulatory network and mechanism of specific agronomic traits and biosynthetic of bioactive components are explored.
Supplemental Material, arsenic_skin_lesion_dose_resp_appendix_2 - Dose-Response Analysis of Exposure to Arsenic in Drinking Water and Risk of Skin Lesions: A Systematic Review of the Literature
Creators: name: Boffetta, Paolo
name: Zunarelli, Carlotta
name: Borron, Claire
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110320 Radiology and Organ Imaging

description: Supplemental Material, arsenic_skin_lesion_dose_resp_appendix_2 for Dose-Response Analysis of Exposure to Arsenic in Drinking Water and Risk of Skin Lesions: A Systematic Review of the Literature by Paolo Boffetta, Carlotta Zunarelli and Claire Borron in Dose-Response
Regional multidisciplinary team approach to the management of placenta accreta spectrum disorder
Creators: name: Yao, Ruofan
name: Nguyen, Hoang Yen
name: Hong, Linda
name: Karagoyzyan, Daniela
name: Burruss, Sigrid
name: Brar, Herb
name: Staton, Michael
name: Martin, Courtney
name: Balli, Kevin
name: Ioffe, Yevgeniya
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: Patients with suspected placenta accreta spectrum (PAS) disorder are often referred to specialized medical centers for antepartum management and definitive treatment via cesarean hysterectomy. In 2019, our institution formed the only multidisciplinary team for the management of PAS within two of the largest counties in California. The purpose of this study was to evaluate the effects of the multidisciplinary team on patient volume and surgical outcomes for patients with PAS. This was a single center retrospective cohort study, based in the only tertiary referral center within two of the largest counties in California. Patients who underwent cesarean hysterectomy for suspected PAS from January 2014 to April 2021 were included and divided into two groups, based on management by the multidisciplinary team from January 2019 and onward or routine care prior to that time. The outcomes of interest were quantitative blood loss, total units of packed red blood cell transfusion, referral volume, and diagnostic accuracy as well as ICU admission, bladder injury, and postoperative length of stay. Furthermore, we wanted to determine if patient’s distance to the hospital impacted outcomes. Normally distributed variables were compared between groups using the t-test. Categorical variables were compared between the two groups using the chi square test. A total of 114 patients were included in the cohort, 59 patients were from January 2014 to December 2018 and 55 patients were from January 2019 to April 2021. Since the establishment of the multidisciplinary center, there was a 2.5-fold increase in the total patient volume (0.8 case/month to 2 cases/month) and a 2.8-fold increase in the referred patient volume. Patients undergoing cesarean hysterectomy since the establishment of the multidisciplinary team had less quantitative blood loss (1500 mL vs 2000 mL, p = .005) and required less units of packed red blood cell transfusion (2 vs 4 units, p < .001). In addition, blood loss of ≥2000 mL decreased from 57.6% to 38.2% (p = .04) and diagnostic accuracy improved from 35.6% to 83.6% (p < .001). Furthermore, we found that patient distance to the hospital did not significantly impact surgical outcomes. Since the establishment of the multidisciplinary team, our center experienced an increase in PAS volume and was able to demonstrate a statistically significant improvement in patient outcomes.
Additional file 5 of Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial
Creators: name: Nakamura, Yoshihiko
name: Hatomoto, Hiroki
name: Yamasaki, Shintaro
name: Yamauchi, Kazuya
name: Kiyomi, Fumiaki
name: Hoshino, Kota
name: Kawano, Yasumasa
name: Nakano, Takafumi
name: Hasegawa, Takehiro
name: Ishikura, Hiroyasu
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 5. Results of primary endpoint analysis after excluding patients with circuit life span of within 24 h.
Supplementary_material – Supplemental material for Verification of ingroup morality promotes willingness to participate in collective action for immigrants’ rights
Creators: name: Vázquez, Alexandra
name: López-Rodríguez, Lucía
name: Gómez, Ángel
name: Brambilla, Marco
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Supplementary_material for Verification of ingroup morality promotes willingness to participate in collective action for immigrants’ rights by Alexandra Vázquez, Lucía López-Rodríguez, Ángel Gómez and Marco Brambilla in Group Processes & Intergroup Relations
Supplemental_Material._Floris_et_al._revised_26.08.20 - Pro-Inflammatory Cytokines at Ultra-Low Dose Exert Anti-Inflammatory Effect In Vitro: A Possible Mode of Action Involving Sub-Micron Particles?
Creators: name: Floris, Ilaria
name: Rose, Thorsten
name: Rojas, Juan Antonio Collado
name: Appel, Kurt
name: Roesch, Camille
name: Lejeune, Beatrice
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 110320 Radiology and Organ Imaging

description: Supplemental_Material._Floris_et_al._revised_26.08.20 for Pro-Inflammatory Cytokines at Ultra-Low Dose Exert Anti-Inflammatory Effect In Vitro: A Possible Mode of Action Involving Sub-Micron Particles? by Ilaria Floris, Thorsten Rose, Juan Antonio Collado Rojas, Kurt Appel, Camille Roesch and Beatrice Lejeune in Dose-Response
The safety of trial of labor after cesarean section (TOLAC) versus elective repeat cesarean section (ERCS): a systematic review and meta-analysis
Creators: name: Qiu, Lili
name: Zhu, Jingjing
name: Lu, Xianyan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Cell Biology
Biotechnology
Science Policy

description: Women’s choice of birth following a cesarean delivery either includes a trial of elective repeat cesarean section (ERCS) or a trial of labor after cesarean (TOLAC). No comprehensive overview or systematic summary is currently available. EMBASE, PubMed, and the Cochrane Library databases were searched from inception to 1 February 2020. Studies reporting the safety of TOLAC and ERCS in pregnant women with prior cesarean delivery were included. Statistical analysis was performed using RevMan 5.3 and Stata 15.0. Odds ratios (ORs) and 95% confidence intervals (CIs) were adopted as the effective measures. A total of 13 studies covering 676,532 cases were included in this meta-analysis. The results demonstrated that the rates of uterine rupture (OR = 3.35, 95%CI [1.57, 7.15], I2 = 81%), neonatal asphyxia (OR = 2.32, 95%CI [1.76, 3.08], I2 = 0%) and perinatal death (OR = 1.71, 95%CI [1.29, 2.25], I2 = 0%) were higher in the TOLAC group compared with the ERCS group. The rates of peripartum hysterectomy (OR = 0.70, 95%CI [0.44, 1.11], I2 = 62%), blood transfusion (OR = 1.24, 95%CI [0.72, 2.12], I2 = 95%), and puerperal infection (OR = 1.11, 95%CI [0.77, 1.60], I2 = 95%) showed no significant differences between the two groups. TOLAC is associated with a higher risk of uterine rupture, neonatal asphyxia, and perinatal death compared with ERCS. Nevertheless, it should be noted that the risks of all complications were small in both groups. This information is important for healthcare providers and women choosing the delivery type.
Association between gestational age at delivery and indicator-specific severe maternal morbidity
Creators: name: Phillips, Jaclyn M.
name: Bodnar, Lisa M.
name: Himes, Katherine P.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Cell Biology
Biotechnology
Mathematical Sciences not elsewhere classified
Computational Biology

description: Individuals who deliver preterm are disproportionately affected by severe maternal morbidity. Limited data suggest that indicator-specific maternal morbidity varies by gestational age at delivery. We sought to evaluate the relationship between gestational age at delivery and the incidence of severe maternal morbidity and indicator-specific severe maternal morbidity. We used a hospital administrative delivery database to identify all singleton deliveries between 16 and 42 weeks gestation from 2002 to 2018. We defined severe maternal morbidity as the presence of any International Classification of Disease diagnosis or procedure codes outlined by the Centers for Disease Control and Prevention, intensive care unit admission, and/or prolonged postpartum hospital length of stay. Indicator-specific severe maternal morbidity was based on the diagnosis and procedure codes and was characterized across gestational age epochs. We categorized gestational age into three epochs to capture extremely preterm birth (less than 28 weeks gestation), preterm birth (28-36 weeks gestation) and term birth (37 weeks gestation and above). Multivariable binomial regression was used to assess the association between categories of gestational age at delivery and severe maternal morbidity adjusting for confounders including age, race, body mass index (BMI), insurance status, and preexisting hypertension or diabetes. Severe maternal morbidity occurred in 2.5% of all deliveries. The unadjusted incidence of severe maternal morbidity by gestational age epoch was 12% at less than 28 weeks gestation, 8.4% at 28 to 36 weeks of gestation, and 1.7% at greater than or equal to 37 weeks gestation. After controlling for potential confounders the predicted probability of severe maternal morbidity was 16% (95% CI 14,17%) at 24 weeks compared to 2.2% (95% CI 2.1,2.3%) at 38 weeks. Sepsis, acute respiratory distress syndrome, mechanical ventilation, and shock were the most common diagnostic codes in deliveries less than 28 weeks gestation. Heart failure and cardiac arrhythmias were more common in patients with severe maternal morbidity delivering at term. A high proportion of severe maternal morbidity occurred in preterm patients, with the highest rates occurring at less than 28 weeks gestation. Individuals with severe maternal morbidity who deliver preterm had distinct indicators of morbidity compared to those who deliver at term.
Mechanisms of Fecal Microbiota Transplantation
Creators: name: 唐镔镔
Publisher: name: CNGB
Year: 2024
Subjects: Raw sequence reads
Multispecies

description: Mechanisms of Fecal Microbiota Transplantation on Spleen Deficiency Syndrome in Irritable Bowel Syndrome with Diarrhea: Insights from Microbiomics and Metabolomics Studies
Application of protein engineering to ene-reductase for the synthesis of chiral compounds through asymmetric reaction
Creators: name: Feng, Jiacheng
name: Ye, Huiru
name: Lu, Changxin
name: Pan, Linyan
name: Chen, Hanchi
name: Zhu, Linjiang
name: Chen, Xiaolong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Ene-reductase (ER) has been widely applied for asymmetrical synthesis of chiral intermediates due to its substrate promiscuity, photoexcited reactivity, and excellent property with producing two chiral centers at a time. Natural ERs often exhibit the same stereoselectivity, and they need to be engineered for opposite configuration of chiral compounds. The hydrogenation process toward activated alkenes by ERs is composed of reductive half reaction and oxidative half reaction, which are dependent upon two cofactors NAD(P)H and flavin mononucleotide. The catalytic activity of ERs will be affected by the size of the substrate, the activating strength of the electron-withdrawing groups, redox potential of cofactors, and the loop flexibility around catalytic cavity. Currently, protein engineering to ERs has been successfully employed to enhance various catalytic properties, including photoexcited asymmetric synthesis. This review summarizes the approaches to reverse the stereoselectivity and enhance catalytic activity of ERs and new applications of the engineered ERs in photobiocatalytic asymmetric synthesis, besides the discussion with the existing molecular mechanisms of mutants regarding the improved catalytic performance.
Additional file 1 of Malaria rapid diagnostic tests reliably detect asymptomatic Plasmodium falciparum infections in school-aged children that are infectious to mosquitoes
Creators: name: Hofer, Lorenz M.
name: Kweyamba, Prisca A.
name: Sayi, Rajabu M.
name: Chabo, Mohamed S.
name: Maitra, Sonali L.
name: Moore, Sarah J.
name: Tambwe, Mgeni M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 1: Oligos used in this study.
Chronic Neurophysiological Effects of Repeated Head Trauma in Retired Australian Male Sport Athletes
Creators: name: Pearce, Alan
name: DJ Kidgell
name: MA Tommerdahl
name: Frazer, Ashlyn
name: Billymo Rist
name: R Mobbs
name: J Batchelor
name: ME Buckland
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Aim: This study investigated the somatosensory and corticomotor physiology of retired contact sport athletes with a history of repeated concussion/subconcussion head trauma. Methods: Retired male athletes with a history of playing contact sports and repeated head trauma (n = 122) were divided into two groups: those who expressed concerns regarding their mental and cognitive health (“symptomatic”: n = 83), and those who did not express any ongoing concerns (“asymptomatic”: n = 39). Both groups were compared to age-matched male controls (n = 50) with no history of concussions or participation in contact sports, an absence of self-reported cognitive, or mood impairments. Transcranial magnetic stimulation (TMS) and vibrotactile stimulation were used to assess corticomotor and somatosensory pathways respectively. TMS and vibrotactile stimulation were correlated to self-reported responses using the Fatigue and Related Symptom Survey. Linear regression was used to associate concussion history with TMS, somatosensory variables. Results: Significant differences were found in symptom survey scores between all groups (p < 0.001). TMS showed significant differences between the “symptomatic” and control groups for intracortical inhibition and paired pulse TMS measures. Somatosensory measures showed significant differences for reaction time (p < 0.01) and reaction time variability (p < 0.01) between the “symptomatic” group to the “asymptomatic” and control groups. For other somatosensory measures, the “symptomatic” measures showed differences to the “control” group. Correlations showed significant associations between severity of symptom reporting with TMS and somatosensory measure, and regression revealed the number of concussions reported was shown to have significant relationships to increased intracortical inhibition and poorer somatosensory performance. Conclusion: This study shows that retired contact sport athletes expressing chronic symptoms showed significant pathophysiology compared to those with no ongoing concerns and non-concussed controls. Further, there is a linear dose-response relationship between number of reported concussions and abnormal neurophysiology. Neurophysiological assessments such as TMS and somatosensory measures represent useful and objective biomarkers to assess cortical impairments and progression of neuropsychological impairment in individuals with a history of repeated head trauma.
title: In Focus: Contraceptive Behaviour
title: Youth Sexuality 9th Iteration. BZgA Fact Sheet
titleType: Subtitle
Creators: name: Scharmanski, Sara
name: Hessling, Angelika
name: Federal Centre For Health Education (BZgA)
Publisher: name: Federal Centre for Health Education (BZgA)
Year: 2021
Subjects: subject: 10000 Social Sciences
subject: adolescence
subject: contraception
subject: prevention
subject: sex education
subject: family planning
subject: condoms
subject: contraceptive pill
subject: emergency contraception
subject: reproductive health
subject: sexual health, reproduktive Gesundheit
subject: sexuelle Gesundheit
subject: Kondome
subject: Notfallkontrazeption
subject: Pille
subject: Adoleszenz
subject: Empfängnisverhütung
subject: Prävention
subject: Sexualaufklärung

description: This fact sheet presents an overview of the contraceptive behaviour of adolescents and young adults in Germany between the ages of 14 and 25.
description: Fact Sheet Sexuality Education, Contraception and Family Planning
description: Face-to-face interview: CAPI/CAMI
description: Self-administered questionnaire: Computer-assisted (CASI)
Remote Volunteering: Publication Round-up
Creators: name: Volden, Nicole
Publisher: name: Zenodo
Year: 2022

description: Abstract of conference oral presentation on Remote Volunteering: Publication Round-up by Geoscience Collections Manager Nicole Volden of Geoscience Collections Manager New Mexico Museum of Natural History and Science Los Lunas United States for SPNHC2022 Conference, Edinburgh. June 5-10th 2022.
Contraceptive counseling and choices in pregnancies with maternal cardiac disease
Creators: name: Shao, Shirley J.
name: Cassidy, Arianna G.
name: Alanizi, Aryn
name: Agarwal, Anushree
name: Sobhani, Nasim C.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Computational Biology

description: Unplanned pregnancies in women with maternal cardiac disease (MCD) are associated with increased morbidity and mortality, but the majority of these individuals do not use highly reliable contraception on postpartum hospital discharge. Contraceptive counseling in this population outside of pregnancy is incomplete and counseling during pregnancy remains poorly characterized. Our objective was to evaluate the provision and quality of contraceptive counseling for individuals with MCD during pregnancy. All individuals with MCD who delivered between 2008 and 2021 at a tertiary care institution with a multidisciplinary cardio-obstetrics team were sent a 27-question survey. A subset of questions were derived from the validated Interpersonal Quality in Family Planning (IQFP) survey, which emphasizes interpersonal connection, adequate information, and decision support for the individual. Each participant received a $15 gift card for survey completion. We performed chart review for clinical and demographic details, including cardiac risk score. Of 522 individuals to whom the survey was sent, 133 responded and met inclusion criteria. Overall, 67% discussed contraception with their general obstetrician, 36% with their maternal-fetal medicine (MFM) specialist, and 24% with their cardiologist. Compared to individuals with low cardiac risk scores, those with high cardiac risk scores had a nonsignificant trend toward being more likely to discuss contraception with a MFM provider (52% vs 33%, p = .08). 65% reported that their provider was ‘excellent’ or ‘good’ in all IQFP domains. Respondents valued providers who respected their autonomy and offered thorough counseling. Respondents disliked feeling pressured or uninformed about the safety of contraceptive options. Most individuals with MCD reported excellent contraceptive counseling during pregnancy. Additional work is needed to understand barriers to and enablers for effective, patient-centered contraceptive counseling and use in this population.
Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Creators: name: Edwards, RJ
name: Field, MA
name: Ferguson, JM
name: Dudchenko, O
name: Keilwagen, J
name: Rosen, BD
name: Johnson, GS
name: Rice, ES
name: Hillier, LD
name: Hammond, JM
name: Towarnicki, SG
name: Omer, A
name: Khan, R
name: Skvortsova, K
name: Bogdanovic, O
name: Zammit, RA
name: Aiden, EL
name: Warren, WC
name: Ballard, John
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Basenjis are considered an ancient dog breed of central African origins that still live and hunt with tribesmen in the African Congo. Nicknamed the barkless dog, Basenjis possess unique phylogeny, geographical origins and traits, making their genome structure of great interest. The increasing number of available canid reference genomes allows us to examine the impact the choice of reference genome makes with regard to reference genome quality and breed relatedness. Results: Here, we report two high quality de novo Basenji genome assemblies: a female, China (CanFam_Bas), and a male, Wags. We conduct pairwise comparisons and report structural variations between assembled genomes of three dog breeds: Basenji (CanFam_Bas), Boxer (CanFam3.1) and German Shepherd Dog (GSD) (CanFam_GSD). CanFam_Bas is superior to CanFam3.1 in terms of genome contiguity and comparable overall to the high quality CanFam_GSD assembly. By aligning short read data from 58 representative dog breeds to three reference genomes, we demonstrate how the choice of reference genome significantly impacts both read mapping and variant detection. Conclusions: The growing number of high-quality canid reference genomes means the choice of reference genome is an increasingly critical decision in subsequent canid variant analyses. The basal position of the Basenji makes it suitable for variant analysis for targeted applications of specific dog breeds. However, we believe more comprehensive analyses across the entire family of canids is more suited to a pangenome approach. Collectively this work highlights the importance the choice of reference genome makes in all variation studies.
Additional file 2 of Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial
Creators: name: Nakamura, Yoshihiko
name: Hatomoto, Hiroki
name: Yamasaki, Shintaro
name: Yamauchi, Kazuya
name: Kiyomi, Fumiaki
name: Hoshino, Kota
name: Kawano, Yasumasa
name: Nakano, Takafumi
name: Hasegawa, Takehiro
name: Ishikura, Hiroyasu
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 2. Cytokine levels at each sampling point.
Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy
Creators: name: Bitto, Natalie
name: Sim, Lesley
name: Johnston, Ella
name: Rishi Pathirana
name: Phan, Thanh
name: Poon, Ivan
name: O'Brien-Simpson, Neil M
name: Hill, Andrew
name: Stinear, Timothy P
name: Liaskos, Maria
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Gram-positive bacteria ubiquitously produce membrane vesicles (MVs), and although they contribute to biological functions, our knowledge regarding their composition and immunogenicity remains limited. Here we examine the morphology, contents and immunostimulatory functions of MVs produced by three Staphylococcus aureus strains; a methicillin resistant clinical isolate, a methicillin sensitive clinical isolate and a laboratory-adapted strain. We observed differences in the number and morphology of MVs produced by each strain and showed that they contain microbe-associated molecular patterns (MAMPs) including protein, nucleic acids and peptidoglycan. Analysis of MV-derived RNA indicated the presence of small RNA (sRNA). Furthermore, we detected variability in the amount and composition of protein, nucleic acid and peptidoglycan cargo carried by MVs from each S. aureus strain. S. aureus MVs activated Toll-like receptor (TLR) 2, 7, 8, 9 and nucleotide-binding oligomerization domain containing protein 2 (NOD2) signalling and promoted cytokine and chemokine release by epithelial cells, thus identifying that MV-associated MAMPs including DNA, RNA and peptidoglycan are detected by pattern recognition receptors (PRRs). Moreover, S. aureus MVs induced the formation of and colocalized with autophagosomes in epithelial cells, while inhibition of lysosomal acidification using bafilomycin A1 resulted in accumulation of autophagosomal puncta that colocalized with MVs, revealing the ability of the host to degrade MVs via autophagy. This study reveals the ability of DNA, RNA and peptidoglycan associated with MVs to activate PRRs in host epithelial cells, and their intracellular degradation via autophagy. These findings advance our understanding of the immunostimulatory roles of Gram-positive bacterial MVs in mediating pathogenesis, and their intracellular fate within the host.
Diet quality and cognitive performance in australian adults aged 55–85 years: A cross-sectional analysis of the hunter community study cohort
Creators: name: PF Li
name: McEvoy, Mark
name: S McKiernan
name: PW Schofield
name: LK Macdonald-Wicks
name: AJ Patterson
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: There is a lack of evidence to determine if diet quality is associated with cognitive performance in older adults. Therefore, the aim of this study was to examine whether diet quality is associated with cognitive performance among older adults. A cross-sectional, secondary analysis of baseline data from the Hunter Community Study (HCS), comparing diet quality, measured using the Australian Recommended Food Score (ARFS), along with validated cognitive performance instruments the Audio Recorded Cognitive Screen (ARCS) and the Mini-Mental State Examination (MMSE) were undertaken in adults aged 55–85 years, living in Newcastle, NSW, Australia. Adjusted linear regression analyses showed that, compared with the lowest ARFS quintile, those in the highest quintile had an ARCS score 5.883 units greater (p < 0.001; R = 0.0098). Furthermore, when quintiles of ARFS score were tested against each ARCS sub-scale score, statistically significant associations were observed with the greatest effect for the Memory (β = 4.055; p = 0.001; R = 0.0065) and Attention (β = 4.136; p = 0.002; R = 0.0047) domains. No statistically significant associations were observed between quintiles of ARFS and MMSE score in the adjusted linear regression analyses. In conclusion, a positive association was observed between diet quality and cognitive performance within this sample of older Australian adults. Further investigation of the above association over time, when follow-up data becomes available, in longitudinal analysis is recommended. 2 2 2
Prenatal ultrasound evaluation of fetal cutaneous hemangioma and related complications
Creators: name: Liao, Minyan
name: He, Bingjia
name: Xiao, Zhen
name: Wang, Limin
name: Chen, Yan
name: Liu, Xiangjiao
name: Shu, Shuang
name: Shang, Ning
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Medicine
Cell Biology
Neuroscience
Biotechnology
Cancer

description: Congenital hemangiomas are rare benign vascular tumors but can lead to serious adverse pregnancy outcomes. Its prenatal diagnosis is a challenge. We explored the clinical applications of prenatal ultrasound for evaluating fetal cutaneous hemangioma and associated complications. A retrospective observational study was conducted comprising a population of pregnant women with fetal cutaneous hemangioma, the latter diagnosed by prenatal ultrasound, between January 2016 and December 2020. The clinical characteristics, sonographic images, complications, and pregnancy outcomes were documented and analyzed. We identified 20 cases of fetal cutaneous hemangioma diagnosed by prenatal ultrasound and confirmed by postpartum examinations. Most hemangiomas were in the head and neck (55%), with either solid isoechoicity (25%) or solid mildly hyperechoic (25%), and well-circumscribed (80%) mass. Eight (40%) fetuses experienced complications, which often occurred in fetuses with large hemangiomas (67% with maximum diameter ≥5 cm; 100% with a volume ≥40 cm3). The most common complications were cardiac-related (88%), including elevated cardiothoracic area ratio, atrioventricular valve regurgitation, and fetal hydrops. A large hemangioma was usually associated with advanced gestational age and a fast hemangioma growth rate. In five (25%) cases, the pregnancy was terminated; these involved hemangioma of the head or neck. One newborn developed Kasabach–Merritt phenomenon, pulmonary hemorrhage and respiratory distress, and died 3 days after birth. Among the 14 (70%) fetuses that survived birth, all hemangiomas disappeared or regressed after treatments with propranolol, interventional surgery, or observed routinely. Prenatal ultrasound examination can accurately diagnose fetal cutaneous hemangioma and related complications to facilitate appropriate management during the pregnancy. Prenatal diagnosis of cutaneous hemangiomas is a clinical challenge. Prenatal ultrasound examination could be a method to accurately diagnose and monitor these hemangiomas.