cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Clinical value of the renal pathologic scoring system in complement-mediated thrombotic microangiopathy
Creators: name: Chen, Fei-Fei
name: Yu, Xiao-Juan
name: Wang, Hui
name: Zhang, Xu
name: Tan, Ying
name: Qu, Zhen
name: Wang, Su-Xia
name: Yu, Feng
name: Chen, Min
name: Zhao, Ming-Hui
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Hematology
subject: Computational Biology

description: This study was initiated to establish a renal thrombotic microangiopathy (TMA) scoring system based on clinical needs and investigate its predictive value for patients’ long-term outcomes. Kidney biopsy-proven Complement-mediated TMA (C-TMA) patients from January 2000 to December 2017 in Peking University First Hospital were retrospectively studied. Both acute and chronic TMA-related lesions, including 15 pathologic indices, were semiquantitatively scored. The interobserver and intraobserver reproducibility and correlation between the pathologic indices and clinical parameters were analyzed. Furthermore, the patients were divided into 2 groups by dialysis use at baseline, and the association of these pathologic indices with their prognostic outcomes was assessed between the two groups. Ninety-two patients with renal biopsy-proven C-TMA were enrolled. All fifteen included pathology indices showed good or moderate interobserver and intraobserver reproducibility and correlated well with several clinical parameters. Several clinicopathological indices were worse in the dialysis group than in the nondialysis group, such as serum creatinine, hemoglobin, platelet count, and estimated glomerular filtration rate. Moreover, morphologic features in the dialysis group presented with more severe vascular lesions. Interstitial fibrosis and chronic tubulointerstitial lesions were related to a trend of high risk of continuous dialysis in the dialysis group. Based on univariate and multivariable Cox regression analysis, more severe glomerular lesions, including glomerular mesangiolysis, glomerular basement membrane double contours and glomerular mesangial proliferation, were identified as risk factors predicting worse prognosis. Our renal C-TMA semiquantitative scoring system is reliable with good reproducibility and prognostic value in clinical practice, which needs further validation.
On the transition from parabolicity to hyperbolicity for a nonlinear equation under Neumann boundary conditions
Creators: name: De Angelis, Monica
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: An integro differential equation which is able to describe the evolution of a large class of dissipative models, is considered. By means of an equivalence, the focus shifts to the perturbed sine- Gordon equation that in superconductivity finds interesting applications in multiple engineering areas. The Neumann boundary problem is considered, and the behaviour of a viscous term, defined by a high order derivative with small diffusion coefficient , is investigated. The Green function, expressed by means of Fourier series, is considered, and an estimate is achieved. Furthermore, some classes of solutions of the hyperbolic equation are determined, proving that there exists at least one solution with bounded derivatives. Results obtained prove that diffusion effects are bounded and tend to zero when e tends to zero.
description: Meccanica (2018). arXiv admin note: text overlap with arXiv:1602.09072
Novel risk-factor analysis and risk-evaluation model of falls in patients receiving maintenance hemodialysis
Creators: name: Liu, Xiaomin
name: Chen, Sijie
name: Liu, Caifei
name: Dang, Xilong
name: Wei, Meng
name: Xin, Xia
name: Gao, Julin
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Neuroscience
Biotechnology
Mental Health

description: This study investigated the prevalence of falls in maintenance hemodialysis (MHD) patients, and established a nomogram model for evaluating the fall risk of MHD patients. This study enrolled 303 MHD patients from the dialysis department of a tertiary hospital in July 2021. The general data of the participants, as well as the scores on the FRAIL scale, Sarcopenia Screening Questionnaire (SARC-F), Short Physical Performance Battery (SPPB) Scale, and of anxiety and depression, and the occurrence of falls were recorded. Using R language, data were assigned to the training set (n = 212) and test set (n = 91), and a logistic regression model was established. The regression model was verified by the receiver operating characteristic (ROC) curve, area under the curve (AUC), and the calibration curve. As a result, the prevalence of falls in MHD patients was 20.46%. Risk factors for falls in the optimal multivariate logistic regression model included hearing impairment, the depression score, and the SPPB score, of which a higher depression score (odds ratio (OR): 1.28, 95% confidence interval (CI): 1.09–1.49, p = 0.002) and SPPB ≤ 6 (ORvsSPPB9-12: 3.69, 95% CI: 1.04–13.14, p = 0.043) conferred independent risk for falls. AUC of the nomogram in the training was 0.773, which in the test group was 0.663. The calibration and standard curves were fitted closely, indicated that the evaluation ability of the model was good. Thus, a higher depression score and SPPB ≤ 6 are independent risk factors for falls in MHD patients, and the nomogram with good accuracy and discrimination that was established in this study has clinical application value.
Actor_ND_X_Partner_Withdrawal_Supplementary_Materials_RandR_v1 - Partners’ Withdrawal When Actors Behave Destructively: Implications for Perceptions of Partners’ Responsiveness and Relationship Satisfaction
Creators: name: Sasaki, Eri
name: Nickola Overall
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Actor_ND_X_Partner_Withdrawal_Supplementary_Materials_RandR_v1 for Partners’ Withdrawal When Actors Behave Destructively: Implications for Perceptions of Partners’ Responsiveness and Relationship Satisfaction by Eri Sasaki and Nickola Overall in Personality and Social Psychology Bulletin
GabrielNakamura/NBT_code_data: First release - preprint and first submission
Creators: name: GabrielNakamura
name: Bruno Mioto
Publisher: name: Zenodo
Year: 2024

description: This release corresponds to the data and R script used for the preprint and first submission of the manuscript "The macroecology of knowledge: Spatio-temporal patterns of name-bearing types in biodiversity science"
Supplemental_Information_Final – Supplemental material for The Role of Interpersonal Sexual Objectification in Heterosexual Intimate Partner Violence From Perspectives of Perceivers and Targets
Creators: name: Sáez, Gemma
name: Riemer, Abigail R.
name: Brock, Rebecca L.
name: Gervais, Sarah J.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, Supplemental_Information_Final for The Role of Interpersonal Sexual Objectification in Heterosexual Intimate Partner Violence From Perspectives of Perceivers and Targets by Gemma Sáez, Abigail R. Riemer, Rebecca L. Brock and Sarah J. Gervais in Journal of Interpersonal Violence
LncTUG1 ameliorates renal tubular fibrosis in experimental diabetic nephropathy through the miR-145-5p/dual-specificity phosphatase 6 axis
Creators: name: Wang, Taoxia
name: Cui, Shubei
name: Liu, Xiaoli
name: Han, Li
name: Duan, Xiaoting
name: Feng, Shuning
name: Zhang, Sen
name: Li, Guiying
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Hematology

description: The renal interstitial fibrosis contributes to the progression and deterioration of diabetic nephropathy (DN). Long noncoding RNA taurine-up-regulated gene 1 (TUG1) in kidneys may be down-regulated by hyperglycemia. We aim to explore its role in tubular fibrosis caused by high glucose and the possible target genes of TUG1. In this study, a streptozocin-induced accelerated DN mouse model and a high glucose-stimulated HK-2 cells model was established to evaluate TUG1 expression. Potential targets of TUG1 were analyzed by online tools and confirmed by luciferase assay. A rescue experiment and gene silencing assay were used to investigate whether TUG1 plays its regulation role via miR-145-5p/dual-specificity phosphatase 6 (DUSP6) in HK2 cells. The effects of TUG1 on inflammation and fibrosis in high glucose treated tubular cells were evaluated by in vitro study, as well as in vivo DN mice model through AAV-TUG1 delivery. Results showed TUG1was downregulated in HK2 cells incubated with high glucose while miR-145-5p was upregulated. Overexpression of TUG1 alleviated renal injury by suppressing inflammation and fibrosis in vivo. Overexpression of TUG1 inhibited HK-2 cell fibrosis and relieved the inflammation. A mechanism study demonstrated that TUG1 directly sponged to miR-145-5p, and DUSP6 was identified as a target downstream of miR-145-5p. In addition, miR-145-5 overexpression and DUSP6 inhibition countervailed the impacts of TUG1. Our findings revealed that TUG1 overexpression alleviates kidney injury in DN mice and decreases the inflammatory response and fibrosis of high glucose-stimulated HK-2 cells via miR-145-5p/DUSP6 axis.
CONSORT_checklist_Jan2020 – Supplemental material for Talking About Weight With Families—Helping Health Care Professionals Start the Conversation: A Nonrandomized Controlled Trial
Creators: name: Bernard-Genest, Julie
name: Chu, Lisa
name: Dettmer, Elizabeth
name: Walsh, Catharine M.
name: McPherson, Amy C.
name: Strub, Jonah
name: Steinberg, Alissa
name: Steinegger, Cathleen
name: Hamilton, Jill K.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111403 Paediatrics
subject: FOS: Clinical medicine

description: Supplemental material, CONSORT_checklist_Jan2020 for Talking About Weight With Families—Helping Health Care Professionals Start the Conversation: A Nonrandomized Controlled Trial by Julie Bernard-Genest, Lisa Chu, Elizabeth Dettmer, Catharine M. Walsh, Amy C. McPherson, Jonah Strub, Alissa Steinberg, Cathleen Steinegger and Jill K. Hamilton in Clinical Pediatrics
Closing the knowledge gap: improving Open Access knowledge sharing between publishers, authors and libraries
Creators: name: Snyder, Livy Onalee
name: Finch, Erica
Publisher: name: Zenodo
Year: 2023

description: Poster presented at the Charleston Conference, 2023. Erica Finch (Scholarly Communication Librarian at Utah State University) and Livy Onalee Snyder (Outreach Associate, Open Book Collective) present their thoughts on 'closing the knowledge gap' and 'improving open access knowledge sharing between publishers, authors, and libraries'. 
description: Funding

The Open Book Futures project is co-funded by Arcadia and Research England Development (RED) Fund (UKRI). Arcadia is a charitable foundation that works to protect nature, preserve cultural heritage and promote open access to knowledge. Since 2002 Arcadia has awarded more than $1 billion to organizations around the world. Research England Development (RED) Fund (UKRI) is a fund supporting institutional-level innovative projects in research and knowledge exchange including collaborations between education providers and between education providers and business.
Predictive Mixing for Density Functional Theory (and other Fixed-Point Problems)
Creators: name: Marks, Laurence
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Density functional theory calculations use a significant fraction of current supercomputing time. The resources required scale with the problem size, internal workings of the code and the number of iterations to convergence, the latter being controlled by what is called mixing. This note describes a new approach to handling trust-regions within these and other fixed-point problems. Rather than adjusting the trust-region based upon improvement, the prior steps are used to estimate what the parameters and trust-regions should be, effectively estimating the optimal Polyak step from the prior history. Detailed results are shown for eight structures using both the Good and Bad Multisecant versions as well as Anderson and a hybrid approach, all with the same predictive method. Additional comparisons are made for thirty-six cases with fixed algorithm Greed The predictive method works well independent of which method is used for the candidate step, and is capable of adapting to different problem types particularly when coupled with the hybrid approach. It would be premature to claim that it is the best possible approach, but the results suggest that it may be.
Long non-coding RNA MALAT1 sponges miR-30c to promote the calcification of human vascular smooth muscle cells by regulating Runx2
Creators: name: Gong, Ying
name: Zhong, Qing
name: Xia, Yunfeng
name: Wen, Yang
name: Gan, Hua
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology

description: Recent evidence suggested that long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play critical roles in the pathogenesis of vascular calcification (VC). In this study, we tried to explore the expression and role of a lncRNA, i.e., metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and a miRNA, i.e., miR-30c, in VC. In vitro VC model was induced in human vascular smooth muscle cells (VSMCs) after 10 days culture in calcifying medium containing 2 mM Na2HPO4. Alizarin red S staining, calcium assay and western blot analysis of runt-related transcription factor 2 (Runx2) and alpha smooth muscle actin (α-SMA) were performed to evaluate VC. Knockdown of MALAT1 and up-regulation of MALAT1, miR-30c and Runx2 was performed to determine the impact of these molecules on VSMCs calcification. Dual-luciferase report assay was performed to confirm the relationship between MALAT1 and miR-30c or miR-30c and Runx2. In addition, quantitative reverse transcription PCR and western blot were used to determine gene and protein expression. MALAT1 was increased, while miR-30c was decreased in calcified VSMCs. Knockdown of MALAT1 suppressed VSMCs calcification; on the contrary, up-regulation of MALAT1 promoted VSMCs calcification. The effect of MALAT1 over-expression on VSMCs calcification was reversed by upregulation of miR-30c, which was reversed again by upregulation of Runx2. Dual-luciferase report assay confirmed that there is a direct interaction between MALAT1 and miR-30c, and Runx2 is a direct target of miR-30c. MALAT1 over-expression promoted VSMCs calcification, which was at least partially through regulating the miR-30c/Runx2 axis.
sj-pdf-1-qch-10.1177_0272684X20918045 - Supplemental material for Effectiveness of Official Development Assistance in the Health Sector in Africa: A Case Study of Uganda
Creators: name: Nguefack, Cyriaque Rene Sobtafo
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-qch-10.1177_0272684X20918045 for Effectiveness of Official Development Assistance in the Health Sector in Africa: A Case Study of Uganda by Cyriaque Rene Sobtafo Nguefack in International Quarterly of Community Health Education
sj-pdf-1-son-10.1177_2377960820927377 - Supplemental material for Repeated Simulation Experience on Self-Confidence, Critical Thinking, and Competence of Nurses and Nursing Students—An Integrative Review
Creators: name: Koukab Abdullah Al Gharibi, MSN
name: Judie Arulappan, MSc(N)
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Medicine
subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-pdf-1-son-10.1177_2377960820927377 for Repeated Simulation Experience on Self-Confidence, Critical Thinking, and Competence of Nurses and Nursing Students—An Integrative Review by Koukab Abdullah Al Gharibi, MSN and Judie Arulappan, MSc(N), PhD, DNSc in SAGE Open Nursing
Appendix_A – Supplemental material for Division of Housework, Communication, and Couples’ Relationship Satisfaction
Creators: name: Carlson, Daniel L.
name: Miller, Amanda J.
name: Rudd, Stephanie
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, Appendix_A for Division of Housework, Communication, and Couples’ Relationship Satisfaction by Daniel L. Carlson, Amanda J. Miller and Stephanie Rudd in Socius
Efficacy and safety of belimumab therapy in lupus nephritis: a systematic review and meta-analysis
Creators: name: Zhang, Han
name: Chen, Juan
name: Zhang, Ying
name: Zhao, Na
name: Xu, Dongmei
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Belimumab is the first biological agent approved for the treatment of systemic lupus erythematosus (SLE), but the efficacy of belimumab for lupus nephritis (LN) is not clear. We conducted this meta-analysis and systematic review to compare the efficacy and safety of belimumab with those of conventional therapy for LN. PubMed, EMBASE, Cochrane Library, Clinical Trials.gov were searched in 31 December 2022 to identify relevant adult human studies reporting effectiveness outcomes of belimumab in patients with LN. Review manager (RevMan 5.4) was used for data analysis with fixed effects model based on heterogeneities. Six randomized controlled trials (RCTs) were included in the quantitative analysis. A total of 2960 participants were identified. Belimumab plus standard therapy significantly improved total renal response rates (RR, 1.31; 95% CI, 1.11–1.53; p = 0.001) and complete renal RRs (1.47; 95% CI, 1.07–2.02; p = 0.02) compared with the control plus standard therapy group. It significantly reduced the risk of renal flare (RR, 0.51; 95% CI, 0.37–0.69; p < 0.001) and renal function worsening or progression to end-stage renal disease (ESRD) (RR, 0.56; 95% CI, 0.40–0.79; p = 0.001). When assessed with the incidence of adverse events, no significant differences between the two groups were observed for the occurrence of treatment-related adverse events (RR, 1.04; 95% CI, 0.99–1.09; p = 0.12). This meta-analysis showed that belimumab plus standard therapy was more effective and had a favorable safety in patients with LN.
Conserving Home: The Birds and the Bay: A more-than-human history of the migratory shorebirds of Warn Marin/Western Port
Creators: name: Gorringe-Smith, Alice Kate Hazel
Publisher: name: Macquarie University
Year: 2025
Subjects: classificationCode: 430307
subject: Environmental history

description: This thesis engages with the role that migratory shorebirds have played in the conservation of Warn Marin/Western Port from colonisation to the present day, and the role that Warn Marin/Western Port plays in the conservation of migratory shorebirds. Placing the more-than- human history (O’Gorman and Gaynor 2020) of the birds’ presence in the bay at the centre of this thesis reinhabits the history of Warn Marin/Western Port with the untold/dismissed stories of the more-than-human world (Lorimer and Hodgetts 2024), and establishes the bay as a multispecies ‘home place’ (van Dooren and Rose 2012). I begin by establishing Warn Marin/Western Port as a multispecies home, and trace the birds’ presence in the bay from pre-colonial times to the twenty-first century. This is placed in the context of Australia’s general categorisation of wetlands since colonisation as extractivist sacrifice zones (Reinert 2018), and examines the role shorebirds have played in disrupting this categorisation by co- creating the bay’s identity as an internationally significant wetland. I examine what makes a place precious, how perceptions of what constitutes ‘home’ in both a human and more-than- human sense fluctuates in Western and Indigenous views of connection to Country, and how these ideas play into the framing of conservation battles. This is informed by an understanding of Warn Marin/Western Port as Bunurong Country. Awareness of the shared imaginary of home, or ‘more-than-human site of coexistence’ (Barry and Suliman 2023), may help to break down ideas of human/nature dualism and motivate future conservation action, and this study investigates if and how understandings of migratory shorebird habitat as home has informed conservation efforts.
Effects of prebiotics, probiotics and synbiotics on serum creatinine in non-dialysis patients: a meta-analysis of randomized controlled trials
Creators: name: Liu, Fenfen
name: Liu, Yang
name: Lv, Xueai
name: Lun, Hengzhong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Science Policy

description: Serum creatinine level are influenced by many factors. Although accumulated data suggested that prebiotics, probiotics and synbiotics supplements could affect serum creatinine level, the results remained controversial. The aim of the present paper was to evaluate the effects of prebiotics, probiotics and synbiotics on serum creatinine in non-dialysis patients. PubMed, EMBASE (Excerpta Medica Database) and the Cochrane Library databases were searched for eligible randomized, controlled trials (RCTs) which were limited to English language studies until 30 September 2022. A random-effects model was performed to analyze the impact of pooled trials. Twelve randomized, controlled trial studies were included in the meta-analysis. Prebiotics, probiotics or synbiotics supplementation did not significantly decrease the serum creatinine levels in non-dialysis patients compared to placebo [standardized mean difference (SMD) = 0.05; 95% confidence interval (CI): (−0.21, 0.31); p = 0.72; I2 = 61%]. The present meta-analysis indicated that supplementation with prebiotics, probiotics and synbiotics could not act as promising adjuvant therapies to decrease the serum creatinine levels in non-dialysis patients.
Supplemental Material 1 - Supplemental material for Phytochemical Investigation of Erodium oxyrrhynchum M. Bieb
Creators: name: Lanyan Jin
name: Fayvush, George
name: Khutsishvili, Manana
name: Atha, Daniel
name: Borris, Robert P.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, Supplemental Material 1, for Phytochemical Investigation of Erodium oxyrrhynchum M. Bieb by Lanyan Jin, George Fayvush, Manana Khutsishvili, Daniel Atha and Robert P. Borris in Natural Product Communications
SM_260320 – Supplemental material for Changing Cognitive Risk Factors for Sexual Aggression: Risky Sexual Scripts, Low Sexual Self-Esteem, Perception of Pornography, and Acceptance of Sexual Coercion
Creators: name: Schuster, Isabell
name: Tomaszewska, Paulina
name: Krahé, Barbara
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, SM_260320 for Changing Cognitive Risk Factors for Sexual Aggression: Risky Sexual Scripts, Low Sexual Self-Esteem, Perception of Pornography, and Acceptance of Sexual Coercion by Isabell Schuster, Paulina Tomaszewska and Barbara Krahé in Journal of Interpersonal Violence
Throwing stones: kidney stone incidence in living kidney donor candidates with increased metabolic risk
Creators: name: Sarwal, Amara
name: Yamauchi, Junji
name: Raghavan, Divya
name: Shihab, Fuad
name: Fornadi, Katalin
name: Rofaiel, George
name: Zimmerman, Michael
name: Campsen, Jeffrey
name: Baker, Nicholas
name: Ganireddy, Yamini Akhila
name: Aviles-Ovalle, Leonardo
name: Baker, Talia
name: Hall, Isaac E.
name: Molnar, Miklos Z.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Virology
subject: Computational Biology

description: Throwing stones: kidney stone incidence in living kidney donor candidates with increased metabolic risk
Input-Output History Feedback Controller for Encrypted Control with Leveled Fully Homomorphic Encryption
Creators: name: Teranishi, Kaoru
name: Sadamoto, Tomonori
name: Kogiso, Kiminao
Publisher: name: arXiv
Year: 2021
Subjects: subject: Systems and Control (eess.SY)
subject: Cryptography and Security (cs.CR)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: Protecting the parameters, states, and input/output signals of a dynamic controller is essential for securely outsourcing its computation to an untrusted third party. Although a fully homomorphic encryption scheme allows the evaluation of controller operations with encrypted data, an encrypted dynamic controller with the encryption scheme destabilizes a closed-loop system or degrades the control performance due to overflow. This paper presents a novel controller representation based on input-output history data to implement an encrypted dynamic controller that operates without destabilization and performance degradation. Implementation of this encrypted dynamic controller representation can be optimized via batching techniques to reduce the time and space complexities. Furthermore, this study analyzes the stability and performance degradation of a closed-loop system caused by the effects of controller encryption. A numerical simulation demonstrates the feasibility of the proposed encrypted control scheme, which inherits the control performance of the original controller at a sufficient level.
description: 12 pages, 7 figures
Tripterygium glycosides improve abnormal lipid deposition in nephrotic syndrome rat models
Creators: name: Zheng, Bidan
name: Lu, Dongfang
name: Chen, Xiuping
name: Yin, Yinghua
name: Chen, Weiying
name: Wang, Xiaowan
name: Lin, Huanmei
name: Xu, Peng
name: Wu, Aihua
name: Liu, Bo
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology

description: The purpose of this study was to determine the effect of tripterygium glycosides (TGs) on regulating abnormal lipid deposition in nephrotic syndrome (NS) rats. Sprague-Dawley (SD) rats were injected with 6 mg/kg doxorubicin to construct nephrotic syndrome models (n = 6 per group), and then administered with TGs (10 mg/kg·d−1), prednisone (6.3 mg/kg·d−1), or pure water for 5 weeks. Biomedical indexes, such as urine protein/creatinine ratio (PCR), blood urea nitrogen (BUN), serum creatinine (Scr), serum albumin (SA), triglycerides (TG), total cholesterol (TC)were investigated to evaluate the renal injury of rats. H&E staining experiment was used to assess the pathological alterations. Oil Red O staining was used to assess the level of renal lipid deposition. Malondialdehyde (MDA) and glutathione (GSH) were measured to assess the extent of oxidative damage to the kidney. TUNEL staining was used to assess the status of apoptosis in the kidney. Western blot analysis was performed to examine the levels of relevant intracellular signaling molecules. After treatment with TGs, those tested biomedical indexes were significantly improved, and the extent of kidney tissue pathological changes and lipid deposition in the kidney was diminished. Treatment with TGs decreased renal oxidative damage and apoptosis. Regarding the molecular mechanism, TGs significantly increased the protein expression levels of Bcl-2 but decreased the levels of CD36, ADFP, Bax, and Cleaved caspase-3. TGs alleviates renal injury and lipid deposition induced by doxorubicin, suggesting that it may be a new strategy for reducing renal lipotoxicity in NS.
sj-pdf-2-smm-10.1177_0962280220925840 - Supplemental material for Robust bivariate random-effects model for accommodating outlying and influential studies in meta-analysis of diagnostic test accuracy studies
Creators: name: Zelalem F Negeri
name: Beyene, Joseph
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-2-smm-10.1177_0962280220925840 for Robust bivariate random-effects model for accommodating outlying and influential studies in meta-analysis of diagnostic test accuracy studies by Zelalem F Negeri and Joseph Beyene in Statistical Methods in Medical Research
Plasma soluble tumor necrosis factor receptor I as a biomarker of lupus nephritis and disease activity in systemic lupus erythematosus patients
Creators: name: Liu, Xin-ran
name: Qi, Yuan-yuan
name: Zhao, Ya-fei
name: Cui, Yan
name: Zhao, Zhan-zheng
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology

description: The goal of our study was to evaluate the potential role of sTNF-RI as a biomarker of renal involvement in SLE patients and active SLE. The study sample consisted of two cohorts. The discovery cohort included 16 SLE patients without renal involvement (non-LN), 60 lupus nephritis (LN) patients and 21 healthy controls (HCs) and the replication cohort included 18 SLE non-LN patients, 116 LN patients and 36 HCs. The sTNF-RI levels differed significantly in the discovery cohort. The plasma sTNF-RI levels were higher in LN patients than in non-LN patients (p = .009) and HCs (p = 4 × 10−6). Plasma sTNF-RI levels were significantly higher in non-LN patients than in HCs (p = .03). The finding was confirmed in independent replication cohort (LNs vs. non-LN, p = 4.053 × 10−7; LNs vs. HCs, p = 2.395 × 10−18; non-LN vs. HCs, p = 2.51 × 10−4). The plasma sTNF-RI levels were associated with disease activity, renal function in SLE patients and urine protein in LN patients. The multivariate analysis revealed that high sTNF-RI was an independent risk factor for renal involvement. The multivariate logistic regression results suggested that high TNF-RI, high systolic blood pressure, high serum creatinine, low C4 and positive anti-dsDNA were independent risks of active SLE patients. A nomogram was constructed based on the results of multivariate logistic regression analysis and it was practical in predicting the risk of the active SLE patients. Immunohistochemistry suggested that the expression of TNF-RI in the kidney was increased. Plasma sTNF-RI might be a good biomarker of renal involvement and disease activity in SLE patients.
online_appendix – Supplemental material for Bad Apples or Bad Orchards? An Organizational Analysis of Educator Cheating on Standardized Accountability Tests
Creators: name: Hibel, Jacob
name: Penn, Daphne M.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Education
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, online_appendix for Bad Apples or Bad Orchards? An Organizational Analysis of Educator Cheating on Standardized Accountability Tests by Jacob Hibel and Daphne M. Penn in Sociology of Education
Mineral and bone disorder after kidney transplantation: a single-center cohort study
Creators: name: Sun, Li
name: Wang, Zijie
name: Zheng, Ming
name: Hang, Zhou
name: Liu, Jiawen
name: Gao, Xiang
name: Gui, Zeping
name: Feng, Dengyuan
name: Zhang, Dongliang
name: Han, Qianguang
name: Fei, Shuang
name: Chen, Hao
name: Tao, Jun
name: Han, Zhijian
name: Ju, Xiaobing
name: Gu, Min
name: Tan, Ruoyun
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology

description: The assessment and prevention of mineral and bone disorder (MBD) in kidney transplant recipients (KTRs) have not been standardized. This study aimed to evaluate MBD one year after kidney transplantation (KT) and identify the influencing factors of MBD. A total of 95 KTRs in our center were enrolled. The changes in bone mineral density (BMD) and bone metabolism biochemical markers, including serum calcium (Ca), phosphorus(P), 25-hydroxyvitamin D(25(OH)vitD), intact parathyroid hormone (iPTH), bone alkaline phosphatase, osteocalcin (OC), type I collagen N-terminal peptide and type I collagen C-terminal peptide (CTx), over one year after KT were assessed. The possible influencing factors of BMD were analyzed. The relationships between bone metabolism biochemical markers were evaluated. The indicators between groups with or without iPTH normalization were also compared. MBD after KT was manifested as an increased prevalence of hypophosphatemia and bone loss, persistent 25(OH)vitD deficiency, and partially decreased PTH and bone turnover markers (BTMs). Femoral neck BMD was positively correlated with body mass index (BMI) and postoperative 25(OH)vitD, and negatively correlated with postoperative PTH. Lumbar spine BMD was positively correlated with BMI and preoperative TG, and negatively correlated with preoperative OC and CTx. BMD loss was positively associated with glucocorticoid accumulation. Preoperative and postoperative iPTH was negatively correlated with postoperative serum P and 25(OH)vitD, and positively correlated with postoperative Ca and BTMs. The recipients without iPTH normalization, who accounted for 41.0% of all KTRs, presented with higher Ca, lower P, higher BTMs, advanced age, and a higher prevalence of preoperative parathyroid hyperplasia. MBD persisted after KT, showing a close relationship with hyperparathyroidism, high bone turnover, and glucocorticoid accumulation.
sj-pdf-1-lec-10.1177_0269094220922823 - Supplemental material for Industrial dynamics in the context of a region’s international competitiveness
Creators: name: Varum, Celeste
name: Guimarães, Carmen
name: Oliveira, José Martinho
name: Martins, Ana
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Economics
subject: Geography
subject: 160607 International Relations
subject: FOS: Political science
subject: 160509 Public Administration
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography
subject: 120599 Urban and Regional Planning not elsewhere classified

description: Supplemental material, sj-pdf-1-lec-10.1177_0269094220922823 for Industrial dynamics in the context of a region’s international competitiveness by Celeste Varum, Carmen Guimarães, José Martinho Oliveira and Ana Martins in Local Economy: The Journal of the Local Economy Policy Unit
The detrimental effects of chronic alcohol consumption on the immune response during murine cytomegalovirus infection
Creators: name: Little, Alexander Armstrong
Publisher: name: Washington State University
Year: 2018
Subjects: Alcohol--Physiological effect
Immune system--Effect of drugs on

description: Alcoholism and alcohol abuse are global problems that were a factor in over 5% of deaths worldwide in 2014. Alcohol consumption has been implicated as a factor in exacerbating communicable diseases by suppressing the immune system and allowing infection or permitting persistent infections to reemerge. Major findings in both epidemiological studies and animal models have demonstrated that alcohol consumption suppresses the immune system, specifically natural killer cells and cytotoxic CD8+ T cells, by reducing cell numbers and their cytotoxicity. Cytomegalovirus (CMV) is a member of the herpesvirus family and infection is very common in humans. Immunocompetent individuals are asymptomatic in due to the immune system's ability to control the infection effectively. However, CMV infection can cause life-threatening complications in immunocompromised individuals such as alcoholics. It is well documented by clinical case reports that CMV infection exacerbates pneumonia, HCV and HIV infection, and life-threatening liver decompensation in human alcoholics, but the progression of CMV infection in alcoholics is poorly understood. Using a chronic alcohol consumption (CAC) mouse model and murine CMV (mCMV) we characterized the progression of acute mCMV infection and how alcohol disrupted the antiviral response. We found that CAC increased the viral load in spleen 4 days post infection, enhanced body weight loss, and inhibited splenomegaly during the acute infection. 12 hours post infection cellular IFN-[beta] and the percentage of IFN-[gamma]-producing NK cells in the spleen were significantly lower in alcohol-consuming mice. Alcohol consumption decreased IL-15-producing dendritic cells in the spleen and liver 36 hours post infection and inhibited NK cell maturation and Ly49H+ NK cell expansion in spleen and liver 3 to 6 days post-infection. Alcohol consumption enhanced NK cell and CD8+ T cell activation, observed as continuous upregulation of CD69 and granzyme B expression in NK and CD8+ T cells in spleen and liver during acute mCMV infection. These results indicate that CAC, by impairing non-specific NK cell and Ly49H+ NK cell activation, exacerbates mCMV infection and compromises viral clearance, which in turn enhances NK cell and CD8+ T cell continuous activation and inflammation resulting in impaired viral clearance, enhanced body weight loss and severe organ damage.
MSJ923970_supplemental_figure – Supplemental material for Five-year longitudinal changes in quantitative spinal cord MRI in multiple sclerosis
Creators: name: Oh, Jiwon
name: Chen, Min
name: Cybulsky, Kateryna
name: Suthiphosuwan, Suradech
name: Seyman, Estelle
name: Dewey, Blake
name: Diener-West, Marie
name: van Zijl, Peter
name: Prince, Jerry
name: Reich, Daniel S
name: Calabresi, Peter A
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care

description: Supplemental material, MSJ923970_supplemental_figure for Five-year longitudinal changes in quantitative spinal cord MRI in multiple sclerosis by Jiwon Oh, Min Chen, Kateryna Cybulsky, Suradech Suthiphosuwan, Estelle Seyman, Blake Dewey, Marie Diener-West, Peter van Zijl, Jerry Prince, Daniel S Reich and Peter A Calabresi in Multiple Sclerosis Journal
GASS_Supplementary_material_revised – Supplemental material for Clinical validation of the self-reported Glasgow Antipsychotic Side-effect Scale using the clinician-rated UKU side-effect scale as gold standard reference
Creators: name: Bock, Marlene Schouby
name: Achter, Oona Nørgaard Van
name: Dines, David
name: Speed, Maria Simonsen
name: Correll, Christoph U
name: Mors, Ole
name: Østergaard, Søren Dinesen
name: Kølbæk, Pernille
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, GASS_Supplementary_material_revised for Clinical validation of the self-reported Glasgow Antipsychotic Side-effect Scale using the clinician-rated UKU side-effect scale as gold standard reference by Marlene Schouby Bock, Oona Nørgaard Van Achter, David Dines, Maria Simonsen Speed, Christoph U Correll, Ole Mors, Søren Dinesen Østergaard and Pernille Kølbæk in Journal of Psychopharmacology
sj-pdf-1-jiv-10.1177_0886260520926310 - Supplemental material for Adverse Childhood Experiences and Adolescent Exposure to Violence
Creators: name: Fagan, Abigail A.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-pdf-1-jiv-10.1177_0886260520926310 for Adverse Childhood Experiences and Adolescent Exposure to Violence by Abigail A. Fagan PhD in Journal of Interpersonal Violence
10.1177_0309364620921290_Supplemental_material – Supplemental material for Two-dimensional video gait analysis: A systematic review of reliability, validity, and best practice considerations
Creators: name: Michelini, Alexandria
name: Arezoo Eshraghi
name: Andrysek, Jan
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, 10.1177_0309364620921290_Supplemental_material for Two-dimensional video gait analysis: A systematic review of reliability, validity, and best practice considerations by Alexandria Michelini, Arezoo Eshraghi and Jan Andrysek in Prosthetics and Orthotics International
Clinical features and outcomes of patients with antineutrophil cytoplasmic antibody-positive systemic lupus erythematosus
Creators: name: Wang, Ying
name: Yu, Xiaoyang
name: Xie, Xinfang
name: Li, Huixian
name: Yang, Wei
name: Liang, Yu
name: Lu, Wanhong
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: To investigate the clinical characteristics, pathological features, and outcomes of patients with antineutrophil cytoplasmic antibody (ANCA)-positive systemic lupus erythematosus (SLE) in northwest China. This retrospective study included 491 patients with SLE tested for ANCA antibodies and 171 patients with ANCA-associated vasculitis (AAV) as controls. Subgroup analysis limited to those with renal involvement, and by ANCA antibody subtype (PR3 vs MPO). To compare the proteinuria remission rates between ANCA-positive and ANCA-negative lupus nephritis (LN) groups, a logistic regression model was used for propensity score matching based on age, hemoglobin, and baseline estimated glomerular filtration rate (eGFR). Compared to ANCA-negative SLE (n = 442), ANCA-positive SLE (n = 46) occur in older patients; however, these patients were younger than those with AAV (n = 167). The eGFR of patients with ANCA-positive LN (n = 25) was higher than that of patients having AAV with renal involvement (n = 56) but lower than that of patients with ANCA-negative LN (n = 163). Patients with SLE who had MPO-ANCA (n = 16) had higher levels of serum creatinine compared to those with PR3-ANCA (n = 30) (156.5 µmol/L vs. 45.5 µmol/L, p = 0.005). During the follow-up period, the remission rate of proteinuria in patients with ANCA-positive LN was lower than that of patients with ANCA-negative LN (50% vs. 75%, p = 0.008). Patients with ANCA-positive LN may have worse baseline renal function and lower protein remission rates compared to patients with ANCA-negative LN. ANCA titers should be regularly monitored throughout the follow-up period in patients with SLE, especially in cases of renal involvement.
10.1177_0309364620923816_Supplementary_material – Supplemental material for Effect of a Spinomed orthosis on balance performance, spinal alignment, joint position sense and back muscle endurance in elderly people with hyperkyphotic posture: A randomized controlled trial
Creators: name: Hosseinabadi, Mostafa
name: Kamyab, Mojtaba
name: Azadinia, Fatemeh
name: Sarrafzadeh, Javad
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, 10.1177_0309364620923816_Supplementary_material for Effect of a Spinomed orthosis on balance performance, spinal alignment, joint position sense and back muscle endurance in elderly people with hyperkyphotic posture: A randomized controlled trial by Mostafa Hosseinabadi, Mojtaba Kamyab, Fatemeh Azadinia and Javad Sarrafzadeh in Prosthetics and Orthotics International
Mitochondrial DNA copy number in peripheral blood of IgA nephropathy: a cross-sectional study
Creators: name: Liu, Jiaqi
name: Wang, Rong
name: Luo, Ning
name: Li, Zhibin
name: Mao, Haiping
name: Zhou, Yi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Cancer
subject: Hematology
subject: Virology

description: Mitochondrial DNA (mtDNA) copy number (CN) is a biomarker of mitochondrial function and has been reported associated with kidney disease. However, its association with IgA nephropathy (IgAN), the most common cause of glomerulonephritis (GN), has not been evaluated. We included 664 patients with biopsy-proven IgAN and measured mtDNA-CN in peripheral blood by multiplexed real-time quantitative polymerase chain reaction (RT-qPCR). We examined the associations between mtDNA-CN and clinical variables and found that patients with higher mtDNA-CN had higher estimated glomerular filtration rate (eGFR) (r = 0.1009, p = .0092) and lower serum creatinine (SCr), blood urea nitrogen (BUN), and uric acid (UA) (r=−0.1101, −0.1023, −0.07806, respectively, all p values <.05). In terms of pathological injury, mtDNA-CN was higher in patients with less mesangial hypercellularity (p = .0385, M0 vs. M1 score by Oxford classification). Multivariable logistic regression analyses also showed that mtDNA-CN was lower for patients with moderate to severe renal impairment (defined as eGFR < 60 mL/min/1.73 m2) vs. mild renal impairment, with the odds ratio of 0.757 (95% confidence interval: 0.579–0.990, p = .042). In conclusion, mtDNA-CN was correlated with better renal function and less pathological injury in patients with IgAN, proposing that systemic mitochondrial dysfunction may be involved in or reflect the development of IgAN.
ON-LINE_APPENDIX – Supplemental material for Undermining a Rival Party’s Issue Competence through Negative Campaigning: Experimental Evidence from the USA, Denmark, and Australia
Creators: name: Seeberg, Henrik Bech
name: Nai, Alessandro
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, ON-LINE_APPENDIX for Undermining a Rival Party’s Issue Competence through Negative Campaigning: Experimental Evidence from the USA, Denmark, and Australia by Henrik Bech Seeberg and Alessandro Nai in Political Studies