cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A general-purpose machine-learning force field for bulk and nanostructured phosphorus
Creators: name: Deringer, Volker L.
name: Caro, Miguel A.
name: Csányi, Gábor
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/639/638/298
/639/301/1034
/639/766/119/1002
/119/118
article

description: Funder: Isaac Newton Trust; doi: https://doi.org/10.13039/501100004815
description: Abstract: Elemental phosphorus is attracting growing interest across fundamental and applied fields of research. However, atomistic simulations of phosphorus have remained an outstanding challenge. Here, we show that a universally applicable force field for phosphorus can be created by machine learning (ML) from a suitably chosen ensemble of quantum-mechanical results. Our model is fitted to density-functional theory plus many-body dispersion (DFT + MBD) data; its accuracy is demonstrated for the exfoliation of black and violet phosphorus (yielding monolayers of “phosphorene” and “hittorfene”); its transferability is shown for the transition between the molecular and network liquid phases. An application to a phosphorene nanoribbon on an experimentally relevant length scale exemplifies the power of accurate and flexible ML-driven force fields for next-generation materials modelling. The methodology promises new insights into phosphorus as well as other structurally complex, e.g., layered solids that are relevant in diverse areas of chemistry, physics, and materials science.
Analytical comparisons of SARS-COV-2 detection by qRT-PCR and ddPCR with multiple primer/probe sets
Creators: name: Liu, Xinjin
name: Feng, Jiangpeng
name: Zhang, Qiuhan
name: Guo, Dong
name: Zhang, Lu
name: Suo, Tao
name: Hu, Wenjia
name: Guo, Ming
name: Wang, Xin
name: Huang, Zhixiang
name: Xiong, Yong
name: Chen, Guozhong
name: Chen, Yu
name: Lan, Ke
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Different primers/probes sets have been developed all over the world for the nucleic acid detection of SARS-CoV-2 by quantitative real time polymerase chain reaction (qRT-PCR) as a standard method. In our recent study, we explored the feasibility of droplet digital PCR (ddPCR) for clinical SARS-CoV-2 nucleic acid detection compared with qRT-PCR using the same primer/probe sets issued by Chinese Center for Disease Control and Prevention (CDC) targeting viral ORF1ab or N gene, which showed that ddPCR could largely minimize the false negatives reports resulted by qRT-PCR [Suo T, Liu X, Feng J, et al. ddPCR: a more sensitive and accurate tool for SARS-CoV-2 detection in low viral load specimens. medRxiv [Internet]. 2020;2020.02.29.20029439. Available from: https://medrxiv.org/content/early/2020/03/06/2020.02.29.20029439.abstract]. Here, we further stringently compared the performance of qRT-PCR and ddPCR for 8 primer/probe sets with the same clinical samples and conditions. Results showed that none of 8 primer/probe sets used in qRT-PCR could significantly distinguish true negatives and positives with low viral load (10−4 dilution). Moreover, false positive reports of qRT-PCR with UCDC-N1, N2 and CCDC-N primers/probes sets were observed. In contrast, ddPCR showed significantly better performance in general for low viral load samples compared to qRT-PCR. Remarkably, the background readouts of ddPCR are relatively lower, which could efficiently reduce the production of false positive reports.
Listroderes obrieni Morrone 1993
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Listroderes
Listroderes obrieni

description: Listroderes obrieni Morrone, 1993
 Listroderes obrieni Morrone, 1993d: 299 (type locality: Chile: Aysén, Coyhaique al Claro; type material: H: CWOB and P: 12 MHNS, 3 MLP, and 1 MZFC).
 Distribution. Southern Chile (Morrone, 1993d).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 32, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Evaluating genotype imputation pipeline for ultra-low coverage ancient genomes
Creators: name: Hui, Ruoyun
name: D’Atanasio, Eugenia
name: Cassidy, Lara M.
name: Scheib, Christiana L.
name: Kivisild, Toomas
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/631/181/19
/631/181/27
/631/181/2474
/631/181/457
article

description: Funder: Sapienza Università di Roma
description: Abstract: Although ancient DNA data have become increasingly more important in studies about past populations, it is often not feasible or practical to obtain high coverage genomes from poorly preserved samples. While methods of accurate genotype imputation from > 1 × coverage data have recently become a routine, a large proportion of ancient samples remain unusable for downstream analyses due to their low coverage. Here, we evaluate a two-step pipeline for the imputation of common variants in ancient genomes at 0.05–1 × coverage. We use the genotype likelihood input mode in Beagle and filter for confident genotypes as the input to impute missing genotypes. This procedure, when tested on ancient genomes, outperforms a single-step imputation from genotype likelihoods, suggesting that current genotype callers do not fully account for errors in ancient sequences and additional quality controls can be beneficial. We compared the effect of various genotype likelihood calling methods, post-calling, pre-imputation and post-imputation filters, different reference panels, as well as different imputation tools. In a Neolithic Hungarian genome, we obtain ~ 90% imputation accuracy for heterozygous common variants at coverage 0.05 × and > 97% accuracy at coverage 0.5 ×. We show that imputation can mitigate, though not eliminate reference bias in ultra-low coverage ancient genomes.
Large-scale social transfer and labor market outcomes: The case of the South African pension program
Creators: name: Matsuda, Norihiko
name: Matsuda, Norihiko
Publisher: name: Unknown
Year: 2016
Subjects: subject: International Development
subject: Labor and Human Capital
subject: Social transfers
subject: Pension
subject: Labor supply
subject: Retirement
subject: South Africa

description: This paper assesses the effects of the South African old age pension program, the largest cash transfer program in the country, on labor force participation and employment of the elderly and prime-aged individuals. During 2008-2010, the minimum eligible age for males gradually decreased from 65 to 60. Exploiting this change as a natural experiment, the paper finds that the pension significantly discouraged the elderly to work. The intention-to-treat effects estimated using three different independent datasets imply that the labor force participation rate of men aged 60-64 significantly decreased by 5.8, 11.3 and 8.9 percentage points, depending on the datasets used. Correspondingly, the probability of being employed decreased by 4.1-11.8 percentage points. The local average treatment effects estimated suggest that once the elderly started to receive the benefit, the probability of participating in the labor force and being employed decreased by 29.4 and 31.6 percentage points respectively although these estimates are not statistically significant. The estimation of the effects for prime-aged individuals, on the other hand, is in progress.
Charge Transfer Excitation Energies From Ground State Density Functional Theory Calculations
Creators: name: Mei, Yuncai
name: Yang, Weitao
Publisher: name: arXiv
Year: 2019
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Calculating charge transfer (CT) excitation energies with high accuracy and low computational cost is a challenging task. Kohn-Sham density functional theory (KS-DFT), due to its efficiency and accuracy, has achieved great success in describing ground state problems. To extend to excited state problems, our group recently demonstrated an approach with good numerical results to calculate low-lying and Rydberg excitation energies of an $N$-electron system from a ground state KS or generalized KS calculations of an $(N-1)$-electron system via its orbital energies. In present work, we explore further the same methodology to describe CT excitations. Numerical results from this work show that performance of conventional density functional approximations (DFAs) is not as good for CT excitations as for other excitations, due to the delocalization error. Applying localized orbital scaling correction (LOSC) to conventional DFAs, a recently developed method in our group to effectively reduce the delocalization error, can improve the results. Overall, the performance of this methodology is better than time dependant DFT (TDDFT) with conventional DFAs. In addition, it shows that results from LOSC-DFAs in this method reach similar accuracy to other methods, such as $Δ$SCF, $G_0W_0$ with Bethe-Salpeter equations, particle-particle random phase approximation, and even high-level wavefunction method like CC2. Our analysis show that the correct $1/R$ trend for CT excitation can be captured from LOSC-DFA calculations, stressing that the application of DFAs with minimal delocalization error is essential within this methodology. This work provides an efficient way to calculate CT excitation energies from ground state DFT.
Penrose Limits and Non-local theories
Creators: name: Hubeny, Veronika E.
name: Rangamani, Mukund
name: Verlinde, Erik
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate Penrose limits of two classes of non-local theories, little string theories and non-commutative gauge theories. Penrose limits of the near-horizon geometry of NS5-branes help to shed some light on the high energy spectrum of little string theories. We attempt to understand renormalization group flow in these theories by considering Penrose limits wherein the null geodesic also has a radial component. In particular, we demonstrate that it is possible to construct a pp-wave spacetime which interpolates between the linear dilaton and the AdS regions for the Type IIA NS5-brane. Similar analysis is considered for the holographic dual geometry to non-commutative field theories.
description: 27 pages, LaTeX; v2: added references
title: Porte-Greffe de Tomate :
title: Principes directeurs pour la conduite de l’examen de la distinction, de l’homogénéité et de la stabilité.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Plants
New Varieties of Plants
Tomato Rootstocks

description: Ces principes directeurs (“principes directeurs d’examen”) visent à approfondir les principes énoncés dans l’introduction générale (document TG/1/3) et dans les documents TGP qui s’y rapportent afin de donner des indications concrètes détaillées pour l’harmonisation de l’examen de la distinction, de l’homogénéité et de la stabilité (DHS) et, en particulier, à identifier des caractères convenant à l’examen DHS et à la production de descriptions variétales harmonisées.
Additional file 4 of Mechanical circulatory support for refractory out-of-hospital cardiac arrest: a Danish nationwide multicenter study
Creators: name: Mørk, Sivagowry Rasalingam
name: Stengaard, Carsten
name: Linde, Louise
name: Møller, Jacob Eifer
name: Jensen, Lisette Okkels
name: Schmidt, Henrik
name: Riber, Lars Peter
name: Andreasen, Jo Bønding
name: Thomassen, Sisse Anette
name: Laugesen, Helle
name: Freeman, Phillip Michael
name: Christensen, Steffen
name: Greisen, Jacob Raben
name: Tang, Mariann
name: Møller-Sørensen, Peter Hasse
name: Holmvang, Lene
name: Gregers, Emilie
name: Kjaergaard, Jesper
name: Hassager, Christian
name: Eiskjær, Hans
name: Terkelsen, Christian Juhl
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Additional file 4. Figure S3: Kaplan-Meier survival curves stratified by groups.
Toy Models of Top Down Causation
Creators: name: Kent, Adrian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: top-down causation
consciousness
panprotopsychism
cellular automata

description: Models in which causation arises from higher level structures as well as from microdynamics may be relevant to unifying quantum theory with classical physics or general relativity. They also give a way of defining a form of panprotopsychist property dualism, in which consciousness and material physics causally affect one another. I describe probabilistic toy models based on cellular automata that illustrate possibilities and difficulties with these ideas.
Introducing MathQA -- A Math-Aware Question Answering System
Creators: name: Schubotz, Moritz
name: Scharpf, Philipp
name: Dudhat, Kaushal
name: Nagar, Yash
name: Hamborg, Felix
name: Gipp, Bela
Publisher: name: arXiv
Year: 2019
Subjects: subject: Information Retrieval (cs.IR)
subject: Computation and Language (cs.CL)
subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: We present an open source math-aware Question Answering System based on Ask Platypus. Our system returns as a single mathematical formula for a natural language question in English or Hindi. This formulae originate from the knowledge-base Wikidata. We translate these formulae to computable data by integrating the calculation engine sympy into our system. This way, users can enter numeric values for the variables occurring in the formula. Moreover, the system loads numeric values for constants occurring in the formula from Wikidata. In a user study, our system outperformed a commercial computational mathematical knowledge engine by 13%. However, the performance of our system heavily depends on the size and quality of the formula data available in Wikidata. Since only a few items in Wikidata contained formulae when we started the project, we facilitated the import process by suggesting formula edits to Wikidata editors. With the simple heuristic that the first formula is significant for the article, 80% of the suggestions were correct.
description: Proceedings of the ACM/IEEE-CS Joint Conference on Digital Libraries (JCDL), Workshop on Knowledge Discovery (2018)
Local productive systems in agri-food supply chains, product specificity and consumer's behaviour: a cognitive approach
Creators: name: Requier-Desjardins, Denis
name: Requier-Desjardins, Denis
Publisher: name: Unknown
Year: 1999
Subjects: subject: Agribusiness
subject: Institutional and Behavioral Economics
subject: Research Methods/ Statistical Methods
subject: consumption technology
subject: learning
subject: territoriality
subject: labelling
subject: proximity
subject: developed and developing countries

description: This paper would like to relate theoretically and empirically, territorial production of typical products, product characteristics and consumer knowledge. It will intertwine two theoretical approaches : • The first one is an approach of "territoriality" which essentially boils down to the existence of specific assets managed by local actors in their interaction process, internal or external. In this setting, spatial proximity is often a proxy for cognitive proximity which enhances innovation processes. • The second one is the approach of the consumption process developed by "New Household Economics, specifically Lancaster, as a "consumption technology" relating products and characteristics. This technology requires that the consumer know the relevant characteristics of products, which can be achieved by "proximity" with the product. By this intertwining we would like to show that the cognitive relationship between the consumer and the product in agri-food markets could be an example of specific asset as long as the knowledge of the product rests on a specific relationship to the area of production. Some examples picked in various countries, developed and developing, will illustrate this point. Labelling seems more likely to emerge in developed countries than in developing ones, as the institutional environment is more reliable. But, in both cases, the feasibility of territorial labelling seems linked to consumer's knowledge and learning as regards territorial characteristics of the product.
Automorphisms of free product-type and their crossed-products
Creators: name: Hiai, Fumio
name: Ueda, Yoshimichi
Publisher: name: arXiv
Year: 2002
Subjects: subject: Operator Algebras (math.OA)
subject: FOS: Mathematics

description: A continuous family of non-outer conjugate aperiodic automorphisms whose crossed-products are all isomorphic is given on every interpolated free group factor. An explicit "duality" relationship between compact co-commutative Kac algebra (minimal) free product actions and free shift actions is also discussed.
description: To appear in Journal of Operator Theory; This paper was written in 2001
The CCFM Monte Carlo generator CASCADE
Creators: name: Jung, H.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: CASCADE is a full hadron level Monte Carlo event generator for e-p, gamma-p and p-p_bar processes, which uses the CCFM evolution equation for the initial state cascade in a backward evolution approach supplemented with off-shell matrix elements for the hard scattering. A detailed program description is given, with emphasis on parameters the user wants to change and common block variables which completely specify the generated events.
description: Program manual, 14 pages
Listroderes paranensis Hustache 1926
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Listroderes
Listroderes paranensis

description: Listroderes paranensis Hustache, 1926
 Listroderes paranensis Hustache, 1926: 199 (type locality: Argentina: Misiones, San Ignacio; type material: H: MNHN); Morrone, 1993d: 304 (= L. costirostris).
 Listroderes costirostris authors (non Schönherr, 1826); Morrone, 1993d: 303 (in part).
 Distribution. Northeastern Argentina (Hustache, 1926).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 32, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
The Princeton Variability Survey
Creators: name: Blake, Cullen
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Princeton Variability Survey (PVS) is a robotic survey which makes use of readily available, ``off-the-shelf'' type hardware products, in conjunction with a powerful set of commercial software products, in order to monitor and discover variable objects in the night sky. The main goal of the PVS has been to devise an automated telescope and data reduction system, requiring only moderate technical and financial resources to assemble, which may be easily replicated by the dedicated amateur, a student group, or a professional and used to study and discover a variety of variable objects, such as stars. This paper describes the hardware and software components of the PVS device as well as observational results from the initial season of the PVS, including the discovery of a new bright variable star.
description: 22 pages, 5 figures. Revised to fix typos and expand discussion. Accepted PASP
Willingness to pay for origin labelled products : a case study of Greek wine consumers
Creators: name: Skuras, Dimitris
name: Vakrou, Alexandra
name: Skuras, Dimitris
name: Vakrou, Alexandra
Publisher: name: Unknown
Year: 1999
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Institutional and Behavioral Economics
subject: origin labelled products
subject: willingness to pay
subject: wine
subject: Greece

description: The European Union has recognised the potential of differentiating quality products and services on a regional basis and introduced Regulation 2081/92 concerning the protection of geographical indications and designations of origin for agricultural products and quality foodstuffs. One of the main objectives of PDOs and PG ls is to enhance credibility of the products in the consumers' eyes. A survey of consumers in the greater Athens area and at the urban centre of the city of Patra collected information about consumer attitudes toward origin labelled wine. A dichotomous choice model is used to identify socio-economic consumer characteristics influencing the willingness to pay for origin wine. Results indicate that wine consumers' willingness to pay vary only according to social and demographic characteristics. Mean willingness to pay was estimated using two alternative econometric specifications of the dichotomous choice model. The results obtained indicate that non-quality wine consumers are willing to pay double the price of a normal table wine bottle if the alternative has a guarantee of place of origin. Their decision is dependent only upon education and place of origin. The models are compared and useful conclusions referring to price policy for origin labelled wines are drawn.
In Vino Veritas : does origin truly matter ?
Creators: name: Steiner, Bodo
name: Steiner, Bodo
Publisher: name: Unknown
Year: 1999
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: product quality
subject: origin
subject: hedonic analysis

description: This paper applies hedonic analysis for an identification of the values which consumers place on attributes of origin as they are listed on the labels of bottles of wine. In particular, region and country of origin are examined with respect to the consumers' degree of product identification. Generalised least squares regressions are employed to infer the implicit valuation of information about wine attributes from explicit market prices in the British off-licence sector. The analysis allows for differential effects between attributes. Where these effects are found to have a significant impact on price, consumers are viewed as regarding attribute bundles as imperfect substitutes. The study identifies these cases where identical grape varieties originate from different countries and regions within those countries. Results suggest that grape varieties are highly important in the choice of Italian and Australian wines, whereas regional origins constitute the most important choice criterion in the case of French wines. The relationship between origin and quality is further explored as marketing implications for retailers are investigated. While considering interactions between the attributes, it is shown what potential gains or losses retailers may have to face as they intend a stocktransfer of wines from different origins.
Elastin-Like Polypeptide Nanoparticles as Carriers for Anti-EGFR Peptide Therapeutics
Creators: name: Tofik, Abdulhakim
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Chemical engineering
subject: FOS: Chemical engineering
subject: Cellular biology
subject: Biochemistry
subject: Oncology
subject: Nanotechnology
subject: FOS: Nanotechnology

description: Peptides have recently gained significant attention for their potential use as therapeutic drugs. However, several challenges hinder their pharmaceutical application, including high production costs, complex synthesis methods, and short in vivo half-lives. This project addresses these challenges by utilizing elastin-like polypeptides (ELPs) as a drug delivery vehicle, taking advantage of their biocompatibility and temperature-responsive self-assembly into micelles. We engineered a novel fusion protein that combines ELP with the Leucine-Rich Repeat 6 (LRR6) domain from human Decorin, which functions as an EGFR antagonist. This design effectively presents LRR6 in a way that preserves its ability to inhibit the epidermal growth factor receptor (EGFR), a receptor whose overexpression drives the growth of many cancers.

Our engineered ELP-LRR6 (ELD6) fusion protein forms micelles at body temperature and achieves EGFR-targeted delivery while acting as the EGFR antagonist to kill tumor cells efficiently. In contrast, ELP micelles, as a control, fail to target EGFR and exert tumor cell-killing activity. By docking tools, we refined the LRR6 to a shorter fragment that maintains its ability to antagonize EGFR and identified the key amino acids within LRR6 responsible for binding to EGFR.

Overall, this work demonstrates the efficiency of ELP micelle, improving both the targeting and bioactivity of peptide drugs like LRR6, representing a promising nanoparticle-based drug delivery system for peptide drugs. Additionally, by integrating molecular docking with experiments, we were able to accelerate the discovery and optimization of peptide drugs.
Integrating Intellectual Property and Sustainable Business Models: The SBM-IP Canvas
Creators: name: Hernández-Chea, Roberto
name: Vimalnath, Pratheeba
name: Bocken, Nancy
name: Tietze, Frank
name: Eppinger, Elisabeth
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: sustainable business models (SBMs)
intellectual property (IP)
sustainability transition
business model canvas
IP strategy

description: Companies attempt to address global sustainability challenges through innovating products, services, and business models. This paper focuses on sustainable business model (SBM) innovations as a way to systemically transform businesses towards sustainability. It has been widely recognized that strategic approaches to using intellectual property (IP) need to be aligned with business model innovation for commercial success. Here we suggest that IP, aligned with SBMs, can also be used to create not only commercial, but also societal and environmental impact. Knowledge about how to best align IP with SBMs to drive sustainability transitions remains limited. We address this gap by developing an SBM-IP canvas that integrates IP considerations into each of the SBM canvas building blocks. We do this by employing relevant theoretical concepts from three literature streams, namely the business model (including SBM), IP, and innovation literature. We use case examples to illustrate different IP considerations that are relevant for the SBM-IP building blocks. These examples show that different IP types (e.g., patents, trademarks) and ways of using them (e.g., more or less restrictive licensing) are applied by companies in relation to the different building blocks. While covering new theoretical ground, the proposed SBM-IP canvas can help decision makers understand how they can use different IP types strategically to propose, create, deliver, and capture sustainable value for society, environment, and the business.
Additional file 8 of Mechanism of Zn2+ regulation of cellulase production in Trichoderma reesei Rut-C30
Creators: name: Li, Ni
name: Li, Jing
name: Chen, Yumeng
name: Shen, Yaling
name: Wei, Dongzhi
name: Wang, Wei
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8: Table S3. The changes of 152 transporter genes in response to Zn2+ stimulus, NS represented not significant, p adjust>0.05
Product Liability Insurance Use Among Tennessee Fruit and Vegetable Farmers
Creators: name: Edwards, Matthew
name: Velandia, Margarita
name: Clark, Christopher D.
name: Lambert, Dayton M.
name: Pepper, Wendell H.
name: Jensen, Kimberly
name: Edwards, Matthew
name: Velandia, Margarita
name: Clark, Christopher D.
name: Lambert, Dayton M.
name: Pepper, Wendell H.
name: Jensen, Kimberly
Publisher: name: Unknown
Year: 2016
Subjects: subject: Marketing
subject: FOS: Economics and business
subject: Risk and Uncertainty
subject: insurance
subject: liability
subject: Tennessee fruit and vegetable farmers
subject: marketing

description: Product liability insurance can help farmers manage product liability risk and gain access to additional market outlets. Data from a survey of Tennessee fruit and vegetable producers were used to evaluate differences between product liability insurance users and non-users, barriers associated with the use of this type of insurance, along with insurance coverage amounts and costs. Findings suggest that primary occupation, percentage of income from farming, size of fruit and vegetable operation, and market outlets used may influence the decision to purchase product liability insurance. Barriers to use include perceived costs of product liability insurance and limited understanding of liability insurance policies.
Supersymmetry Breaking and Composite Extra Dimensions
Creators: name: Luty, Markus A.
name: Sundrum, Raman
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study supergravity models in four dimensions where the hidden sector is superconformal and strongly-coupled over several decades of energy below the Planck scale, before undergoing spontaneous breakdown of scale invariance and supersymmetry. We show that large anomalous dimensions can suppress Kahler contact terms between the hidden and visible sectors, leading to models in which the hidden sector is "sequestered" and anomaly-mediated supersymmetry breaking can naturally dominate, thus solving the supersymmetric flavor problem. We construct simple, explicit models of the hidden sector based on supersymmetric QCD in the conformal window. The present approach can be usefully interpreted as having an extra dimension responsible for sequestering replaced by the many states of a (spontaneously-broken) strongly-coupled superconformal hidden sector, as dictated by the AdS/CFT correspondence.
description: References added. 16 pages, LaTeX2e, no figures
Typicality, a judgement support for the wine critique
Creators: name: Teil, Geneviève
name: Teil, Geneviève
Publisher: name: Unknown
Year: 1999
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: typicality
subject: wines
subject: wine critique
subject: quality markets
subject: sociology

description: This paper examines the role "typicality" can play in the concrete quality wine market organisation. "Typicality" is often denounced as being an illusion, a kind of purely social construct used to enhance sales, create scarcity and high prices. These assumptions imply that the goodness of produce can be immediately perceived. The anthropological study of this particular market and the focus on the perception of quality show on the contrary that it is not. Quality is the result of the wine critique's work and "typicality" is an intermediary notion that helps the wine critique to judge the wines. So rather than being a purely economic notion, the production of "typicality" appears to be fairly similar to the production of style in other artistic domains, and the denominations of origin are closer to author's rights than to economic measures designed to produce scarcity.
Listroderes robustior Schenkling and Marshall 1931
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Listroderes
Listroderes robustior

description: Listroderes robustior Schenkling and Marshall, 1931
 Listroderes robustus Germain, 1895: 64 (non Waterhouse, 1841) (type locality: Chile: Copiapó; type material: L: MHNS and PL: 5 MHNS and 4 NZAC).
 Listroderes robustior Schenkling and Marshall, 1931: 9 (replacement name for L. robustus Germain, 1895).
 Distribution. Northern and southern Chile (Morrone, 1993d).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 32, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Additional file 1 of Structured regularization based velocity structure estimation in local earthquake tomography for the adaptation to velocity discontinuities
Creators: name: Yamanaka, Yohta
name: Kurata, Sumito
name: Yano, Keisuke
name: Komaki, Fumiyasu
name: Shiina, Takahiro
name: Kato, Aitaro
Publisher: name: figshare
Year: 2022
Subjects: subject: Geophysics
subject: FOS: Earth and related environmental sciences

description: Additional file 1. Additional figures.
Additional file 1 of Adherence and characteristics of participants enrolled in a standardised programme of patient education and exercises for low back pain, GLA:D® Back – a prospective observational study
Creators: name: Ris, Inge
name: Broholm, Daniel
name: Hartvigsen, Jan
name: Andersen, Tonny Elmose
name: Kongsted, Alice
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Science Policy
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
The origin, typicality and quality of agro-food products: the territory as input for the enterprise
Creators: name: Albisinni, Ferdinando
name: Venzi, Lorenzo
name: Albisinni, Ferdinando
name: Venzi, Lorenzo
Publisher: name: Unknown
Year: 1999
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Community/Rural/Urban Development
subject: territory
subject: quality of agro-food products
subject: origin

description: The paper, after a brief summary of the economic relevance of the "territory" considered here as a "production input" at large, available to the firm, examines some relevant legal aspects and the historical developments of linking the territory to the value of products in the law-making-process by the European Community and later the Union. On this basis is performed a more detailed analysis of three case studies [olive oil, beef and bottling QWPDR (Quality Wines Produced in Specific Regions)] and tentative conclusions about these issues are drawn.
Additional file 1 of An investigation of the association between religious coping, fatigue, anxiety and depressive symptoms during the COVID-19 pandemic in Morocco: a web-based cross-sectional survey
Creators: name: Btissame Zarrouq
name: Nivine Abbas
name: Hilaly, Jaouad El
name: Asri, Achraf El
name: Abbouyi, Samira
name: Omari, Majid
name: Malki, Hicham
name: Bouazza, Samira
name: Moutawakkil, Salma Ghofrane
name: Halim, Karima
name: Ragala, Mohammed Elamine
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1.
An Embedding Lemma in Soft Topological Spaces
Creators: name: Nordo, Giorgio
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Topology (math.GN)
subject: FOS: Mathematics
subject: 54A40

description: In 1999, Molodtsov initiated the concept of Soft Sets Theory as a new mathematical tool and a completely different approach for dealing with uncertainties in many fields of applied sciences. In 2011, Shabir and Naz introduced and studied the theory of soft topological spaces, also defining and investigating many new soft properties as generalization of the classical ones. In this paper, we introduce the notions of soft separation between soft points and soft closed sets in order to obtain a generalization of the well-known Embedding Lemma for soft topological spaces.
The Non-Ideal Organic Electrochemical Transistors Impedance
Creators: name: Pecqueur, Sébastien
name: Lončaric, Ivor
name: Zlatić, Vinko
name: Vuillaume, Dominique
name: Crljen, Željko
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Organic electrochemical transistors offer powerful functionalities for biosensors and neuroinspired electronics, with still much to understand on the time dependent behavior of this electrochemical device. Here, we report on distributed element modeling of the impedance of such microfabricated device, systematically performed under a large concentration variation for KCl(aq) and CaCl2(aq). We propose a new model which takes into account three main deviations to ideality, that were systematically observed, caused by both the materials and the device complexity, over large frequency range (1 Hz to 1 MHz). More than introducing more freedom degree, the introduction of these non redundant parameters and the study of their behaviors as function of the electrolyte concentration and applied voltage give a more detailed picture of the OECT working principles. This optimized model can be further useful for improving OECT performances in many applications (e.g. biosensors, neuroinspired devices) and circuit simulations.
description: Full paper with supporting information
Pathogenic Escherichia coli Possess Elevated Growth Rates under Exposure to Sub-Inhibitory Concentrations of Azithromycin
Creators: name: Tuan-Anh, Tran
name: Tuyen, Ha Thanh
name: Minh Chau, Nguyen Ngoc
name: Toan, Nguyen Duc
name: Triet, Tran Hanh
name: Triet, Le Minh
name: Trang, Nguyen Hoang Thu
name: To, Nguyen Thi Nguyen
name: Bartholdson Scott, Josefin
name: The, Hao Chung
name: Thanh, Duy Pham
name: Clapham, Hannah
name: Baker, Stephen
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Escherichia coli
azithromycin
tetracycline
growth rate
fitness cost
antimicrobial resistance
resistome
morphology
physiology

description: Antimicrobial resistance (AMR) has been identified by the World Health Organization (WHO) as one of the ten major threats to global health. Advances in technology, including whole-genome sequencing, have provided new insights into the origin and mechanisms of AMR. However, our understanding of the short-term impact of antimicrobial pressure and resistance on the physiology of bacterial populations is limited. We aimed to investigate morphological and physiological responses of clinical isolates of E. coli under short-term exposure to key antimicrobials. We performed whole-genome sequencing on twenty-seven E. coli isolates isolated from children with sepsis to evaluate their AMR gene content. We assessed their antimicrobial susceptibility profile and measured their growth dynamics and morphological characteristics under exposure to varying concentrations of ciprofloxacin, ceftriaxone, tetracycline, gentamicin, and azithromycin. AMR was common, with all organisms resistant to at least one antimicrobial; a total of 81.5% were multi-drug-resistant (MDR). We observed an association between resistance profile and morphological characteristics of the E. coli over a three-hour exposure to antimicrobials. Growth dynamics experiments demonstrated that resistance to tetracycline promoted the growth of E. coli under antimicrobial-free conditions, while resistance to the other antimicrobials incurred a fitness cost. Notably, antimicrobial exposure heterogeneously suppressed bacterial growth, but sub-MIC concentrations of azithromycin increased the maximum growth rate of the clinical isolates. Our results outline complex interactions between organism and antimicrobials and raise clinical concerns regarding exposure of sub-MIC concentrations of specific antimicrobials.
Design, synthesis, and biological evaluation of novel triazoloquinazolinone derivatives as SHP2 protein inhibitors
Creators: name: Luo, Rongshuang
name: Wang, Zhongyuan
name: Luo, Dali
name: Qin, Yumei
name: Zhao, Chunshen
name: Yang, Di
name: Lu, Tian
name: Zhou, Zhixu
name: Huang, Zhuyan
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: A novel series of triazoloquinazolinone derivatives were designed, synthesised, and evaluated for their in vitro biological activities against the SHP2 protein. Moreover, some compounds were evaluated against A375 cells. The results revealed that target compounds possessed moderate to excellent inhibitory activity against SHP2 protein, whereas compounds 12f, 12l, 12j, 17e, and 17f have strong antiproliferative activity on A375 cells. The compound 12l showed remarkable cytotoxicity against A375 cells and a strong inhibitory effect against SHP2 protein when compared with SHP244. The structure-activity relationships (SARs) indicated that electron-donating groups (EDGs) on phenyl rings are beneficial for improving the antitumor activity; compounds with a hydroxyl substituent at the 2-position of phenyl ring exhibited superior activities than compounds with a substituent at the 4-position. In addition, compound 12l displayed improved physicochemical properties as well as metabolic stability compared to SHP244. Our efforts identified 12l as a promising SHP2 protein inhibitor, warranting its further investigation.
The IDEAL framework in neurosurgery: a bibliometric analysis
Creators: name: Ota, Helen C. U.
name: Smith, Brandon G.
name: Alamri, Alexander
name: Robertson, Faith C.
name: Marcus, Hani
name: Hirst, Allison
name: Broekman, Marike
name: Hutchinson, Peter
name: McCulloch, Peter
name: Kolias, Angelos
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Review Article - Neurosurgical technique evaluation
Neurosurgical technique evaluation
Research
Evidence
Innovation
Neurosurgery
Surgery
IDEAL framework

description: Funder: University of Cambridge
description: Abstract: Background: The Idea, Development, Exploration, Assessment and Long-term study (IDEAL) framework was created to provide a structured way for assessing and evaluating novel surgical techniques and devices. Objectives: The aim of this paper was to investigate the utilization of the IDEAL framework within neurosurgery, and to identify factors influencing implementation. Methods: A bibliometric analysis of the 7 key IDEAL papers on Scopus, PubMed, Embase, Web of Science, and Google Scholar databases (2009–2019) was performed. A second journal-specific search then identified additional papers citing the IDEAL framework. Publications identified were screened by two independent reviewers to select neurosurgery-specific articles. Results: The citation search identified 1336 articles. The journal search identified another 16 articles. Following deduplication and review, 51 relevant articles remained; 14 primary papers (27%) and 37 secondary papers (73%). Of the primary papers, 5 (36%) papers applied the IDEAL framework to their research correctly; two were aligned to the pre-IDEAL stage, one to the Idea and Development stages, and two to the Exploration stage. Of the secondary papers, 21 (57%) explicitly discussed the IDEAL framework. Eighteen (86%) of these were supportive of implementing the framework, while one was not, and two were neutral. Conclusion: The adoption of the IDEAL framework in neurosurgery has been slow, particularly for early-stage neurosurgical techniques and inventions. However, the largely positive reviews in secondary literature suggest potential for increased use that may be achieved with education and publicity.
On Stabilization of Maxwell-BMS Algebra
Creators: name: Concha, P.
name: Safari, H. R.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this work we present different infinite dimensional algebras which appear as deformations of the asymptotic symmetry of the three-dimensional Chern-Simons gravity for the Maxwell algebra. We study rigidity and stability of the infinite dimensional enhancement of the Maxwell algebra. In particular, we show that three copies of the Witt algebra and the BMS3+Witt algebra are obtained by deforming its ideal part. New family of infinite dimensional algebras are obtained by considering deformations of the other commutators which we have denoted as M(a,b;c,d) and \bar{M}(\barα,\barβ;\barν). Interestingly, for the specific values a=c=d=0, b=-\frac{1}{2} the obtained algebra M(0,-\frac{1}{2};0,0) corresponds to the twisted Schrodinger-Virasoro algebra. The central extensions of our results are also explored. The physical implications and relevance of the deformed algebras introduced here are discussed along the work.
description: 27 pages
Gauge invariant formulation of systems with second class constraints
Creators: name: Stephany, J.
name: Restuccia, A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A covariant quantization method for physical systems with reducible constraints is presented.
description: 4 pages, XIX International Colloquium in Group Theoretical Methods in Physics, Salamanca, Spain, 1992
An empirical model to evaluate the effects of environmental humidity on the formation of wrinkled, creased and porous fibre morphology from electrospinning
Creators: name: Zhang, Duo
name: Davoodi, Pooya
name: Li, Xia
name: Liu, Ye
name: Wang, Wenyu
name: Huang, Yan Yan Shery
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Article
/639/301/1034
/639/166/898
/639/925/930/1032
article

description: Abstract: Controlling environmental humidity level and thus moisture interaction with an electrospinning solution jet has led to a fascinating range of polymer fibre morphological features; these include surface wrinkles, creases and surface/internal porosity at the individual fibre level. Here, by cross-correlating literature data of far-field electrospinning (FFES), together with our experimental data from near-field electrospinning (NFES), we propose a theoretical model, which can account, phenomenologically, for the onset of fibre microstructures formation from electrospinning solutions made of a hydrophobic polymer dissolved in a water-miscible or polar solvent. This empirical model provides a quantitative evaluation on how the evaporating solvent vapour could prevent or disrupt water vapor condensation onto the electrospinning jet; thus, on the condition where vapor condensation does occur, morphological features will form on the surface, or bulk of the fibre. A wide range of polymer systems, including polystyrene, poly(methyl methacrylate), poly-l-lactic acid, polycaprolactone were tested and validated. Our analysis points to the different operation regimes associated FFES versus NFES, when it comes to the system’s sensitivity towards environmental moisture. Our proposed model may further be used to guide the process in creating desirable fibre microstructure.
Approaching Wonderland
Creators: name: Normann, Ben David
name: Hervik, Sigbjørn
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Continuing previous work, we show the existence of stable, anisotropic future attractors in Bianchi invariant sets with a $p$-form field ($p\,\in\,\{1,3\}$) and a perfect fluid. In particular, we consider the not previously investigated Bianchi invariant sets $\mathcal{B}$(II), $\mathcal{B}$(IV), $\mathcal{B}$(VII$_0$) and $\mathcal{B}$(VII$_{h})$ and examine their asymptotic behaviour. We find that the isolated equilibrium set Wonderland is a future attractor on all of its existence ($2/3
description: 42 pages, 6 figures