cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: The importance of optimizing the field of view in order to minimise patient dose. An audit of CT KUB scanning technique.
Creators: name: Karthigan, Ravindran
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Performed at one institution
subject: Observational
subject: Retrospective
subject: Education and training
subject: Radiation safety
subject: Education
subject: CT
subject: Urinary Tract / Bladder
subject: Radioprotection / Radiation dose
subject: Genitourinary

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Urinary stone disease is common, with a lifetime prevalence of 12% for men and 6% for women.(1) Renal colic is a descriptor of the acute-onset, spasmodic loin pain that occurs when a urinary stone obstructs the ureter, leading to distension of...
Inclusion of neutral guests by water-soluble macrocyclic hosts – a comparative thermodynamic investigation with cyclodextrins, calixarenes and cucurbiturils
Creators: name: Guo, Dong-Sheng
name: D. Uzunova, Vanya
name: Assaf, Khaleel I.
name: Lazar, Alexandra I.
name: Liu, Yu
name: Nau, Werner M.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: The driving forces of association between three different families of macrocycles as hosts, namely cyclodextrins (α-, β-, and γ-), p-sulfonatocalix[n]arenes (n = 4–6) as well as cucurbit[n]urils (n = 6–8), and three different bicyclic azoalkane homologues as guests, namely 2,3-diazabicyclo[2.2.1]hept-2-ene (DBH), 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) as well as 2,3-diazabicyclo[2.2.3]non-2-ene (DBN), were examined by means of calorimetric titrations, NMR spectroscopy and molecular dynamics simulation, all in aqueous solution. The small, spherical and uncharged guests preferably bind inside the cavities of the medium sized hosts. The inclusion complexation by β-cyclodextrin and p-sulfonatocalix[4]arene shows medium binding affinities (millimolar), while cucurbit[7]uril macrocycle shows very strong binding (micromolar). For all types of macrocycles, the complex formation is enthalpically driven (ΔH° < 0), accompanied by slightly unfavourable entropy changes (ΔS° < 0). The results are discussed in terms of the flexibility of the hosts, the hydrophobic character of their cavities and the release of high-energy water upon binding, and generalised by including two additional guests, the ketones cyclopentanone and (+)-camphor.
title: Low dose angioCT ine the evaluation of aortic vasculitis
Creators: name: Habouchi, Amine
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Observational
subject: Prospective
subject: Dosimetric comparison
subject: Computer Applications-Detection, diagnosis
subject: CT-Angiography
subject: Arteries / Aorta
subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Performed at one institution

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Takayasu disease is an inflammatoryperiaortitisinvolving large and medium sizevessels (1).​ Rare vasculitis, women of eastern Asia (2)​ The diagnostic relies on multiple clinical andradiological criteria(1), (2), (3), (4), (5).​...
Skaftafellsjökull, Iceland: glacial geomorphology recording glacier recession since the Little Ice Age
Creators: name: Evans, David J. A.
name: Ewertowski, Marek
name: Orton, Chris
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: A 1:5700 scale map of the recently deglaciated foreland of Skaftafellsjökull, Iceland as it appeared in 2007, depicts a typical active temperate glacial landsystem with a clear pattern of sequentially changing push moraine morphologies, including remarkable hairpin-shaped moraines, indicative of spatial and temporal variability in process-form regimes in glacier sub-marginal settings. Similar to other Icelandic glacier forelands, this demonstrates that the piedmont glacier lobes of the region have developed strong longitudinal crevassing and well-developed ice-marginal pecten during their historical recession from the Little Ice Age maximum moraines, likely driven by extending ice flow and poorly drained sub-marginal conditions typical of the uncovering of overdeepenings. Additionally, the localized development of a linear tract of kame and kettle topography is interpreted as the geomorphic and sedimentary signature of thrust stacked and gradually melting debris-rich glacier ice, a feature hitherto unrecognized in the Icelandic active temperate lobe landsystem signature.
Lost in datification? The journey of data from the primary source to the final interpretation
Creators: name: Bruno, Enrica
name: Baroncini, Sofia
Publisher: name: Zenodo
Year: 2024
Subjects: subject: RDF data for humanities
subject: RDF data quality
subject: Literature studies
subject: Art history

description: Slides and results of the evaluation performed for testing the approach proposed in the talk Lost in datification? The journey of data from the primary source to the final interpretation presented at the conference MeTe digitali. Mediterraneo in rete tra testi e contesti (AIUCD2024).
title: X-ray and more x-rays in preterm neonates: are we doing the right thing?
Creators: name: Urtasun, Agustina
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Performed at one institution
subject: Observational
subject: Retrospective
subject: Dosimetric comparison
subject: Radiation safety
subject: Fluoroscopy
subject: Digital radiography
subject: CT
subject: Radioprotection / Radiation dose
subject: Paediatric
subject: Action 7 - Radiation protection of children

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Continued improvement of medical care has decreased the mortality of very premature births. The higher number of preterm neonates (PN) results in higher acuity patients and extended hospital stays, and a consequence needs for diagnostic exams. As...
title: Entrance surface doses among adults undergoing posteroanterior plain chest radiography at two selected tertiary hospitals in Kampala Uganda.
Creators: name: Kato, Nsereko
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Multicentre study
subject: Cross-sectional study
subject: Prospective
subject: Quality assurance
subject: Dosimetry
subject: Conventional radiography
subject: Radioprotection / Radiation dose
subject: Action 2 - Clinical diagnostic reference levels (DRLs)

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Recent studies have shown that low radiation doses typical of those in medical imaging may induce malignancies. This creates a need for safe use of radiation during medical exposure. To promote safe radiation use, the Bonn call for action (2012)...
Sesquiterpene-neolignans from Manglietia hookeri
Creators: name: Hu, Xiaoqing
name: Sui, Xianjin
name: Wang, Yijing
name: Wang, Wenshu
name: Wu, Haibo
name: Zhang, Feiran
name: Tan, Yuna
name: Zhang, Feng
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: The comet assay-guided fractionation of the twigs of Manglietia hookeri resulted in the isolation of three sesquiterpene-neolignans, including a new one 5-allyl-2-(4-allyl-phenoxy)-3-[7-(1-hydroxy-1-methyl-ethyl)-1, 4a-dimethyl-decahydro-naphthalen-1-yloxy]-phenol (1), and eudesobovatol A (2) and eudesobovatol B (3), together with three lignans, obovatol (4), honokiol (5) and magnolol (6). Their structures were elucidated on the basis of spectral analysis and by comparison with related literature data. Compounds 1, 4–6 showed a protective effect on UV inductive DNA damage in mice lymphocyte cells, while compound 1 indicated the smallest Olive Tail Moment 7.34 ± 2.09 at 6 × 10−6 μM.
title: Early implementation phase of new BSS-based regulations (EU 13/59) in Ireland: structures, systems and self-assessment.
Creators: name: Brennan, David
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Not applicable
subject: Workforce
subject: Occupational / Environmental hazards
subject: Education and training
subject: Audit and standards
subject: PACS
subject: Radiation physics
subject: Management
subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Not applicable

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: The publishing of the European Basic Safety Standard (BSS) Directive 2013/59 necessitated the enactment of new Irish legislation for radiation safety. This poster reviews the early phase practical implementation of the directive, successes and...
title: What about the radiation in Crohn's disease?
Creators: name: Linhares Moreira, Ana Sofia
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Performed at one institution
subject: Observational
subject: Retrospective
subject: Education and training
subject: Dosimetric comparison
subject: Education
subject: Diagnostic procedure
subject: Audit and standards
subject: CT
subject: Radioprotection / Radiation dose
subject: Gastrointestinal tract
subject: GI Tract

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Chron’s disease (CD) is a primarily gastrointestinal inflammatory disease. Any portion of the gastrointestinal tract may be involved, but the small bowel is affected alone in about a third of patients and the terminal ileum is affected in 90% of...
A new pyrone derivative from an endophytic Aspergillus tubingensis of Lycium ruthenicum
Creators: name: Ma, Yang-min
name: Li, Ting
name: Ma, Cong-cong
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: A new pyrone named 6-isovaleryl-4-methoxy-pyran-2-one (1), along with three known pyrone compounds, rubrofusarin B (2), asperpyrones A (3) and campyrone A (4), was isolated from fermentation of Aspergillus tubingensis in Lycium ruthenicum. Their structures were confirmed by spectroscopic techniques, such as IR, NMR and HRESI-MS. Compound 2 indicated strong inhibitory activity against Escherichia coli, with MIC value of 1.95 μg/mL.
title: Radiation protection journey at DHA children hospital
Creators: name: POTTY, BINDU
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Action 7 - Radiation protection of children
subject: Paediatric
subject: Fluoroscopy
subject: Diagnostic procedure
subject: Dosimetric comparison
subject: Retrospective
subject: Diagnostic or prognostic study
subject: Performed at one institution

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: The aim of this poster is to present the Fluoroscopic doses for paediatric patients and the radiation protection optimization implemented for the common fluoroscopic procedures in DHA (Dubai Health Authority) - Children hospital . DHA is committed...
Dosimetric advantages of a clinical daily adaptive plan selection strategy compared with a non-adaptive strategy in cervical cancer radiation therapy
Creators: name: Agustinus J. A. J. Van De Schoot
name: Boer, Peter De
name: Visser, Jorrit
name: Stalpers, Lukas J. A.
name: Rasch, Coen R. N.
name: Bel, Arjan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Background: Radiation therapy (RT) using a daily plan selection adaptive strategy can be applied to account for interfraction organ motion while limiting organ at risk dose. The aim of this study was to quantify the dosimetric consequences of daily plan selection compared with non-adaptive RT in cervical cancer. Material and methods: Ten consecutive patients who received pelvic irradiation, planning CTs (full and empty bladder), weekly post-fraction CTs and pre-fraction CBCTs were included. Non-adaptive plans were generated based on the PTV defined using the full bladder planning CT. For the adaptive strategy, multiple PTVs were created based on both planning CTs by ITVs of the primary CTVs (i.e., GTV, cervix, corpus-uterus and upper part of the vagina) and corresponding library plans were generated. Daily CBCTs were rigidly aligned to the full bladder planning CT for plan selection. For daily plan recalculation, selected CTs based on initial similarity were deformably registered to CBCTs. Differences in daily target coverage (D98% > 95%) and in V0.5Gy, V1.5Gy, V2Gy, D50% and D2% for rectum, bladder and bowel were assessed. Results: Non-adaptive RT showed inadequate primary CTV coverage in 17% of the daily fractions. Plan selection compensated for anatomical changes and improved primary CTV coverage significantly (p p 0.5Gy, V1.5Gy, V2Gy, D50% and D2%. However, daily plan selection significantly increased the bladder V1.5Gy, V2Gy, D50% and D2%. Conclusions: In cervical cancer RT, a non-adaptive strategy led to inadequate target coverage for individual patients. Daily plan selection corrected for day-to-day anatomical variations and resulted in adequate target coverage in all fractions. The dose to bowel and rectum was decreased significantly when applying adaptive RT.
Distribution of thifluzamide, fenoxanil and tebuconazole in rice paddy and dietary risk assessment
Creators: name: Fu, Yan
name: Zheng, Zuntao
name: Wei, Peng
name: Wang, Mengcen
name: Liu, Yihua
name: Zhu, Guonian
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Cell Biology

description: Distribution behaviors of thifluzamide, fenoxanil, and tebuconazole applied to rice were investigated in South China. Analysis was by a modified QuEChERS method with gas chromatography (thifluzamide and fenoxanil) and liquid chromatography mass spectrometry (tebuconazole). Thifluzamide and tebuconazole partitioned mainly into the soil, with half-lives in the paddy soil of 12–14 and 5.3–7.8 days, respectively. Fenoxanil partitioned mainly into the rice plants, with half-lives of 3.3–4.4 days. The half-lives of thifluzamide, fenoxanil, and tebuconazole in paddy water were 0.17–0.89, 1.8–3.0, and 1.6–4.0 days, respectively. The residues in rice grains at the pre-harvest interval of 14 days were all below the established maximum limit values. The dietary risks assessed as hazard quotients at the pre-harvest interval were less than 1.
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer
Creators: name: Lund, Kjersti V.
name: Simonsen, Trude G.
name: Kristensen, Gunnar B.
name: Rofstad, Einar K.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) may provide prognostic biomarkers for cervix carcinoma. We have shown previously that the early phase of the signal intensity-versus-time curve (SITC) may have significant prognostic power. The purpose of the present investigation was to explore the prognostic value of the late phase of the SITC. Material and methods: DCE-MRI data of 80 patients (FIGO stage IB–IVA) treated with concurrent chemoradiotherapy were examined. Four parameters were calculated from the late-phase SITC: tumor volume with decreasing signal, tumor fraction with decreasing signal, tumor volume with increasing signal (TVIS), and tumor fraction with increasing signal. Results: Multivariate analysis involving clinical parameters and late-phase SITC parameters suggested that TVIS is a strong independent prognostic factor for both disease-free and overall survival. When early-phase SITC parameters were included in the multivariate analysis, the early-phase SITC, but not the late-phase SITC, was found to have independent prognostic value. Conclusion: The late-phase SITC can provide prognostic factors for the outcome of cervix carcinoma, that is, a large tumor volume with increasing late-phase SITCs is associated with poor outcome. However, the prognostic power of the late-phase SITC is not as strong as that of the early-phase SITC.
Distinguishing underlying and surface variation patterns in speech perception
Creators: name: Lawyer, Laurel A.
name: Corina, David P.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: This study examines the relationship between patterns of variation and speech perception using two English prefixes: “in-”/“im-” and “un-”. In natural speech, “in-” varies due to an underlying process of phonological assimilation, while “un-” shows a pattern of surface variation, assimilating before labial stems. In a go/no-go lexical decision experiment, subjects were presented a set of “mispronounced” stimuli in which the prefix nasal was altered (replacing [n] with [m], or vice versa), in addition to real words with unaltered prefixes. No significant differences between prefixes were found in responses to unaltered words. In mispronounced items, responses to “un-” forms were faster and more accurate than to “in-” forms, although a significant interaction mitigated this effect in labial contexts. These results suggest the regularity of variation patterns has consequences for the lexical specification of words, and argues against radical underspecification accounts which argue for a maximally sparse lexicon.
title: More opportunities than risks: the 10 most relevant topics of radiation protection in 2020
Creators: name: Kainberger, Franz
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Not applicable
subject: Not applicable
subject: Quality assurance
subject: Dosimetric comparison
subject: Health policy and practice
subject: Dosimetry
subject: Computer Applications-General
subject: Teleradiology
subject: CT
subject: Radioprotection / Radiation dose
subject: Management
subject: Action 8 - Radiation protection training and learning material

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: With the current actions in radiation protection the focus is on improving the safety culture with an holistic and interprofessional approach aiming at building trust between patients and all involved healthcare professionals. The Radiation...
Screening for the ancient polar bear mitochondrial genome reveals low integration of mitochondrial pseudogenes (numts) in bears
Creators: name: Fritjof Lammers
name: Janke, Axel
name: Rücklé, Cornelia
name: Zizka, Vera
name: Nilsson, Maria A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Cancer
subject: 60506 Virology

description: Phylogenetic analyses of nuclear and mitochondrial genomes indicate that polar bears captured the brown bear mitochondrial genome 160,000 years ago, leading to an extinction of the original polar bear mitochondrial genome. However, mitochondrial DNA occasionally integrates into the nuclear genome, forming pseudogenes called numts (nuclear mitochondrial integrations). Screening the polar bear genome identified only 13 numts. Genomic analyses of two additional ursine bears and giant panda indicate that all except one of the discovered numts entered the bear lineage at least 14 million years ago. However, short read genome assemblies might lead to an under-representation of numts or other repetitive sequences. Our findings suggest low integration rates of numts in bears and a loss of the original polar bear mitochondrial genome.
title: The structured referral: enhancing the justification process according to the Basic Safety Standards Directive
Creators: name: Kainberger, Franz
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Not applicable
subject: Not applicable
subject: Quality assurance
subject: Radiation safety
subject: Health policy and practice
subject: Dosimetry
subject: Nuclear medicine conventional
subject: CT
subject: CAD
subject: Radioprotection / Radiation dose
subject: Professional issues
subject: Management
subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Not applicable

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: For the justification of imaging, with ESRiGuide a success has been achieved by developing and adopting appropriateness criteria and by implementing them as a computerized decision support tool. By following the Basic Safety Standards Directive...
Feasibility of preference-driven radiotherapy dose treatment planning to support shared decision making in anal cancer
Creators: name: Rønde, Heidi S.
name: Wee, Leonard
name: Pløen, John
name: Appelt, Ane L.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Purpose/Objective: Chemo-radiotherapy is an established primary curative treatment for anal cancer, but clinically equal rationale for different target doses exists. If joint preferences (physician and patient) are used to determine acceptable tradeoffs in radiotherapy treatment planning, multiple dose plans must be simultaneously explored. We quantified the degree to which different toxicity priorities might be incorporated into treatment plan selection, to elucidate the feasible decision space for shared decision making in anal cancer radiotherapy. Material and methods: Retrospective plans were generated for 22 anal cancer patients. Multi-criteria optimization handles dynamically changing priorities between clinical objectives while meeting fixed clinical constraints. Four unique dose distributions were designed to represent a wide span of clinically relevant objectives: high-dose preference (60.2 Gy tumor boost and 50.4 Gy to elective nodes with physician-defined order of priorities), low-dose preference (53.75 Gy tumor boost, 45 Gy to elective nodes, physician-defined priorities), bowel sparing preference (lower dose levels and priority for bowel avoidance) and bladder sparing preference (lower dose levels and priority for bladder avoidance). Results: Plans satisfied constraints for target coverage. A senior oncologist approved a random subset of plans for quality assurance. Compared to a high-dose preference, bowel sparing was clinically meaningful at the lower prescribed dose [median change in V45Gy: 234 cm3; inter-quartile range (66; 247); p 45Gy: 281 cm3; (73; 488); p 35Gy: 13.7%-points; (0.3; 30.6); p 35Gy: 30.3%-points; (12.4; 43.1); p Conclusions: There is decision space available in anal cancer radiotherapy to incorporate preferences, although tradeoffs are highly patient-dependent. This study demonstrates that preference-informed dose planning is feasible for clinical studies utilizing shared decision making.
title: Awareness of Clinical Imaging Guidelines and Radiation Protection among referrers in Sub-Saharan Africa; a case study of Mengo Hospital, Uganda.
Creators: name: Kawooya, Micheal
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Head and neck
subject: Radiographers
subject: Radioprotection / Radiation dose
subject: CT
subject: CT-Angiography
subject: CT-High Resolution
subject: Decision analysis
subject: Education
subject: Safety
subject: Education and training
subject: Patterns of Care
subject: Quality assurance
subject: Not applicable
subject: Cross-sectional study
subject: Performed at one institution

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Inappropriate imaging confers risk to patients especially when it involves the use of ionizing radiation. Awareness for Clinical Imaging Guidelines (CIGs) and radiation protection (RP) may help improve the appropriateness of imaging. Clinical...
Preparation of γ-aminopropyltriethoxysilane cross-linked poly(aspartic acid) superabsorbent hydrogels without organic solvent
Creators: name: Zhang, Xin
name: Tan, Tianwei
name: Cao, Hui
name: Meng, Hongyu
name: Sun, Shenyu
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Engineering
Biochemistry
Biophysics

description: Poly(aspartic acid) (PASP) hydrogel is a type of biodegradable and biocompatible polymer with high water absorbing ability. Traditionally, the production of PASP hydrogel is expensive, complex, environmentally unfriendly, and consumes a large amount of organic solvents, e.g. dimethylformamide or dimethylsulfoxide. This study introduces a one-step synthesis of PASP resin, in which the organic phase was replaced by distilled water and γ-aminopropyltriethoxysilane was used as the cross-linker. Absorbent ability and characteristics were determined by swelling ratio, FTIR, 13C SSNMR, and SEM. In vitro cytotoxicity evaluation and animal skin irritation tests showed the hydrogel has body-friendly properties. Preparing PASP hydrogel in aqueous solution is promising and finds its use in many applications.
title: A case report: a proper patient shielding at pediatric extremity radiography examinations
Creators: name: Verius, Michael
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Performed at one institution
subject: Not applicable
subject: Retrospective
subject: Pathology
subject: Diagnostic procedure
subject: Conventional radiography
subject: Radioprotection / Radiation dose
subject: Paediatric
subject: Extremities
subject: Action 7 - Radiation protection of children

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: In this study we present a case report of pediatric hand x-ray examination. For some reason at times false estimation of the Region-Of-Interest leads to false reconstructions of the final x-ray image and to a retake. The reason for this behaviour is...
title: Effectiveness of Clinical Imaging Guidelines in the reduction of inappropriate requisitions in Sub-Saharan Africa; a case study of Mengo Hospital, Uganda.
Creators: name: Kawooya, Micheal
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Action 1 - Guidelines, implementation policies, and Clinical Decision Support (ESR iGuide)
subject: Head and neck
subject: Radiographers
subject: Radioprotection / Radiation dose
subject: CT
subject: CT-Angiography
subject: CT-High Resolution
subject: Audit and standards
subject: Decision analysis
subject: Efficacy studies
subject: Outcomes
subject: Patterns of Care
subject: Quality assurance
subject: Not applicable
subject: Cross-sectional study
subject: Performed at one institution

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Ionizing radiation has revolutionized the practice of medicine. The availability of diagnostic imaging has prompted inappropriate use over the past century. Clinical Imaging Guidelines (CIGs) have been demonstrated to reduce such inappropriate use....
title: What are the consequences of increasing the dose modulation ceiling in order to improve CT image quality?
Creators: name: Joyce, Stella
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Performed at one institution
subject: Experimental
subject: Prospective
subject: Dosimetric comparison
subject: Technical aspects
subject: Dosimetry
subject: Comparative studies
subject: CT
subject: Abdomen
subject: Action 3 - Image quality assessment based on clinical indications

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Computed tomography (CT) image quality is described in terms of contrast, spatial resolution, image noise and artifact. Visualisation of certain intra-abdominal structures with CT may be limited by noise, and is therefore closely associated with...
Chemical constituents of the mangrove-associated fungus Capnodium sp. SZ-F22. A new eremophilane sesquiterpene
Creators: name: He, Haibing
name: Ma, Zhongjun
name: Wang, Qianqian
name: Liu, Yu
name: Xu, Hualin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: A new eremophilane sesquiterpene, capnodiumone (1), along with five known eremophilane sesquiterpenes (2–6) and eight other compounds (7–14), have been isolated from a mangrove-associated fungus Capnodium sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth extract of the fungus exhibited a good inhibitory effect on the mycelium growth against Fusarium graminearum at 100 μg/mL, however, all the 14 compounds showed no expected antifungal activity. The probable reasons were discussed.
Modeling, simulation and analysis of mechanochemical patterns in active tissues
Creators: name: BAJPAI, SUPRIYA
Publisher: name: Monash University
Year: 2022
Subjects: Biophysics
Computational Physics
Computational Biology

description: Cell mechanics and cell-cell signaling are expected to play important roles in determining the tissue organization and patterning during morphogenesis. Modeling efforts have, thus far, treated these two processes separately. Experiments in recent years, however, suggest that both these processes could be tightly coupled. Hence, in the present thesis, we propose a vertex model to study how the dynamics of cell polarity and migration influence the spatiotemporal patterning of signaling molecules such as Delta and Notch. We then extend this vertex model framework to include a simple feedback mechanism between cell-cell adhesion and the expression of signaling molecules in cells to explore the origin and diverse manifestation of chemical and cell morphological patterns in the tissues.
title: AI3SD Interview with Professor Matthew Todd
Creators: name: Pauli, Michelle
Publisher: name: University of Southampton
Year: 2020
Subjects: subject: AI3SD, Interview, Artificial Intelligence, Drug Discovery, Drug Candidates, Machine Learning

description: This interview forms part of our AI3SD Interview Series. Professor Matthew Todd, a Professor of Drug Discovery from University College London was interviewed by Michelle Pauli at our AI3SD Network+ Conference in 2019. Matthew is a PI on one of the funding projects from AI3SD-FundingCall1.
title: Does automatic capture of data on dose indices generate different Diagnostic Reference Levels than manual capture?
Creators: name: Chatfield, Mythreyi
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Multicentre study
subject: Observational
subject: Retrospective
subject: Patterns of Care
subject: Screening
subject: CT
subject: Radiation physics
subject: Lung
subject: Action 2 - Clinical diagnostic reference levels (DRLs)

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: There are ongoing efforts worldwide to develop Diagnostic Reference Levels (DRLs) and keep them updated [1-3]. One persistent challenge of this effort is to be able to gather accurate data with minimal burden of the providers. Automated data...
In silico study on β-aminoketone derivatives as thyroid hormone receptor inhibitors: a combined 3D-QSAR and molecular docking study
Creators: name: Wang, Fang-Fang
name: Yang, Wei
name: Shi, Yong-Hui
name: Le, Guo-Wei
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biophysics
Biochemistry
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer

description: In order to explore the structure–activity correlation of a series of β-aminoketone analogs as inhibitors of thyroid hormone receptor (TR), a set of three-dimensional quantitative structure–activity relationship (3D-QSAR) models based on comparative molecular field analysis (CoMFA) and comparative molecular similarity analysis (CoMSIA), for the first time, were developed in the present work. The best CoMFA model with steric and electrostatic fields exhibited , for TRβ, and , for TRα. 3D contour maps produced from the optimal models were further analyzed individually, which provide the areas in space where interactive fields would affect the inhibitory activity. In addition, the binding modes of inhibitors at the active site of TRs were examined using molecular docking, the results indicated that this series of inhibitors fit into the active site of TRs by forming hydrogen bonding and electrostatic interactions. The docking studies also revealed that Leu305, Val458 for TRβ, and Asp407 for TRα are showing hydrogen bonds with the most active inhibitors. In any case, the 3D-QSAR models combined with the binding information will serve as a useful approach to explore the chemical space for improving the activity of TRβ and TRα inhibitors.
title: 01_2305
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Can perceivers recognise emotions from spontaneous expressions?
Creators: name: Disa A. Sauter
name: Fischer, Agneta H.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Posed stimuli dominate the study of nonverbal communication of emotion, but concerns have been raised that the use of posed stimuli may inflate recognition accuracy relative to spontaneous expressions. Here, we compare recognition of emotions from spontaneous expressions with that of matched posed stimuli. Participants made forced-choice judgments about the expressed emotion and whether the expression was spontaneous, and rated expressions on intensity (Experiments 1 and 2) and prototypicality (Experiment 2). Listeners were able to accurately infer emotions from both posed and spontaneous expressions, from auditory, visual, and audiovisual cues. Furthermore, perceived intensity and prototypicality were found to play a role in the accurate recognition of emotion, particularly from spontaneous expressions. Our findings demonstrate that perceivers can reliably recognise emotions from spontaneous expressions, and that depending on the comparison set, recognition levels can even be equivalent to that of posed stimulus sets.
title: “Energy Print” project: a regional project to optimize doses in Andalusian population.
Creators: name: Valdes Solis, Pablo
Publisher: name: ESR EuroSafe Imaging
Year: 2020
Subjects: subject: Multicentre study
subject: Not applicable
subject: Quality assurance
subject: Education and training
subject: Dosimetric comparison
subject: eLearning
subject: Computer Applications-General
subject: Audit and standards
subject: CT
subject: Radioprotection / Radiation dose
subject: Action 4 - Dose management systems

description: Background/introduction Description of activity and work performed Conclusion and recommendations Personal/organisational information References
description: Background/introduction: Andalusia Andalusia( Fig. 1 ) is an autonomous community in southern Spain . It is the most populous, and the second largest autonomous community in Spain. The Andalusian autonomous community is of- ficially recognised as a "historical nationality"....
WEBINAR: Protection of genomic data and the Australian Privacy Act: when is genomic data 'personal information'?
Creators: name: Taylor, Mark
Publisher: name: Zenodo
Year: 2022
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Genomics
subject: Genetic data
subject: Personal information
subject: Health information
subject: Privacy
subject: http://edamontology.org/topic_0091
subject: http://edamontology.org/topic_0622

description: This record includes training materials associated with the Australian BioCommons webinar ‘Protection of genomic data and the Australian Privacy Act: when is genomic data ‘personal information’?’. This webinar took place on 6 April 2022. Event description  It is easy to assume that genomic data will be captured by legal definitions of ‘health information’ and ‘genetic information’, but the legal meaning of ‘genetic information’ need not align with scientific categories. There are many different types of genomic data, with varied characteristics, uses and applications. Clarifying when genomic data is covered by the Privacy Act 1988 (Cth) is an ongoing evaluative exercise but is important for at least 3 reasons: those subject to the Privacy Act need to be able to confidently navigate their responsibilities understanding current controls is a prerequisite for meaningful external critique (and this is particularly important at a time when the Privacy Act is under review), and while legislation that applies to state public sector agencies is generally distinct from the Privacy Act there are similarities that extend the relevance of the question when is genomic data ‘personal information’ under the Privacy Act? In this presentation, Mark will explore the relationship between the legal concept of genetic information and the concept of genomic data relevant to health and medical research, reflect on the characteristics of each, and the possibility Materials are shared under a Creative Commons Attribution 4.0 International agreement unless otherwise specified and were current at the time of the event. Files and materials included in this record: Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc. Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file. Taylor_Slides (PDF): A PDF copy of the slides presented during the webinar. Materials shared elsewhere: A recording of this webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/Iaei-9Gu-AI
Characterization of a new Lactobacillus salivarius strain engineered to express IBV multi-epitope antigens by chromosomal integration
Creators: name: Ma, Bing-cun
name: Yang, Xin
name: Wang, Hong-ning
name: Cao, Hai-peng
name: Xu, Peng-wei
name: Ding, Meng-die
name: Liu, Hui
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: To obtain adhesive and safe lactic acid bacteria (LAB) strains for expressing heterologous antigens, we screened LAB inhabitants in intestine of Tibetan chickens by analyzing their adhesion and safety properties and the selected LAB was engineered to express heterologous antigen (UTEpi C-A) based on chromosomal integration strategy. We demonstrated that a new Lactobacillu salivarius TCMM17 strain is strongly adhesive to chicken intestinal epithelial cells, contains no endogenous plasmids, is susceptible to tested antimicrobials, and shows no toxicities. In order to examine the potential of TCMM17 strain as heterogenous antigen delivering vehicle, we introduced a UTEpi C-A expression cassette in its chromosome by constructing a non-replicative plasmid (pORI280-UUTEpi C-AD). The recombinant TCMM17 strain (∆TCMM17) stably was found to keep the gene cassette through 50 generations, and successfully displayed EpiC encoded by the cassette on its surface. This work provides a universal platform for development of novel oral vaccines and expression of further antigens of avian pathogens. Schematic representation of the non-replicative integration plasmid pORI280-UUTEpi C-AD construction and the overview of the homologous recombination strategy.
Photosensitizer-assembled PEGylated graphene-copper sulfide nanohybrids as a synergistic near-infrared phototherapeutic agent
Creators: name: Wu, Chunhui
name: Li, Dan
name: Yang, Hong
name: Liu, Yiyao
name: Zhu, Anni
name: Wang, Lianhui
name: Zeng, Hongjuan
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Medicine
subject: Biochemistry

description: Objectives: Stimulative nanostructures play a crucial role in developing the smart nanomedicine for high therapeutic efficacy with minimum adverse effects. Herein, a near-infrared (NIR) light-responsive nanohybrids p-nanographene oxide (GO)-copper sulfide (CuS)/indocyanine green (ICG) comprised of GO, CuS nanoparticles and photosensitizer ICG was fabricated to couple the photothermal property of CuS and photodynamic effect of ICG in one system in order to achieve the synergistic phototherapy.Methods: pGO-CuS/ICG was constructed by self-assembling ICG on pGO-CuS nanostructure. Its physicochemical, photothermal and photodynamic properties were studied by spectroscopic methods. The in vitro cellular uptake, cytotoxicity, the single/combined photothermal therapeutic (PTT) and photodynamic therapeutic (PDT) effects were investigated with biological techniques.Results: pGO-CuS/ICG exhibited high efficacy of photothermal conversation and singlet oxygen generation under NIR laser excitation. It entered into the target cancer cells probably via passive transmembrane pathway and exerted obvious PTT and PDT effect against the tumor cells upon irradiation with the respective 940 and 808 nm lasers. In particular, the tremendous synergistic efficacy of PDT and PTT had been demonstrated by tuning the NIR laser combined irradiation.Conclusions: This study promises the future applications of pGO-CuS/ICG as a NIR light activable theranostic nanodrug for deep-seated cancer noninvasive phototherapy.