cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The use of simulation as a decision tool for improvements in sawmill manufacturing
Creators: name: Thoews, Steven Eric
Publisher: name: University of British Columbia
Year: 2008

description: A simulation study was used to analyze the flow of products though a sawmill in order to determine where productivity improvements could be made. The sawmill analyzed is located in the interior of British Columbia, and processes a variety of species and products. The mill was selected for this reason, as it was important to determine how a change in the process will affect the piece flow and production of the various species. A simulation model of the mill was developed using the Arena 8.0 discrete event simulation software developed by Rockwell Automation. Data consisting of mill layout and flow, breakdown patterns, machine process times and downtimes, conveyor speeds, and buffer capacities were collected from the sawmill. This information was used to layout the framework in a conceptual model. The conceptual model was then used to develop the simulation model in Arena. A face validity test, combined with comparisons of model output to actual mill output was used to determine the validity of the model. After running several different scenarios processing Larch, White pine, and Ponderosa pine, it was discovered that the trimmer was the system bottleneck when both the small log and large log lines were running throughout the shift. Running under base case conditions, the model predicted an average board output of 13,147 boards. An increase in the processing capability of the trimmer resulted in the bottleneck to shift to the edger from the small log line. The OptQuest Analyzer program bundled with the Arena software was used to further analyze the shift in bottleneck to the edger from the small log line. By allowing the program to manipulate machine settings for the trimmer and edger, it was able to maximize the average board output to 17,996 boards per shift when no edger set up times were considered. If the edger setup times are used, the average board output dropped to 16,708 boards per shift. These findings were presented to the sawmill management and based on the study, they proceeded to make improvements at the trimmer. The improvements resulted in an increase of 10% to sawmill output.
Demographic and Parental Influences on Breakfast Consumption Rates
Creators: name: Kruse, Kerri
Publisher: name: Health New Zealand
Year: 2024
Subjects: classificationCode: 420603
subject: Health promotion

description: Promoting breakfast eating among children has many benefits, including improved cognitive and physical abilities, increased likelihood of meeting the recommendations for fruit and vegetable intake, and decreased unhealthy snacking. The Ministry of Health’s Food and Nutrition Guidelines highlight the importance of eating three healthy meals every day, including breakfast.The Breakfast-eaters programme run by the Health Promotion Agency (HPA) encourages families with children to eat a healthy breakfast every day. HPA monitors both children’s and their parents/caregivers’ breakfast eating habits in the Health and Lifestyles Survey (HLS), as parental breakfast consumption has been found to be an important predictor of whether a child eats breakfast or not.
Improving attenuation corrections obtained using singles-mode transmission data in small-animal PET
Creators: name: Vandervoort, Eric
Publisher: name: University of British Columbia
Year: 2008

description: The images in positron emission tomography (PET) represent three dimensional dynamic distributions of biologically interesting molecules labelled with positron emitting radionuclides (radiotracers). Spatial localisation of the radio-tracers is achieved by detecting in coincidence two collinear photons which are emitted when the positron annihilates with an ordinary electron. In order to obtain quantitatively accurate images in PET, it is necessary to correct for the effects of photon attenuation within the subject being imaged. These corrections can be obtained using singles-mode photon transmission scanning. Although suitable for small animal PET, these scans are subject to high amounts of contamination from scattered photons. Currently, no accurate correction exists to account for scatter in these data. The primary purpose of this work was to implement and validate an analytical scatter correction for PET transmission scanning. In order to isolate the effects of scatter, we developed a simulation tool which was validated using experimental transmission data. We then presented an analytical scatter correction for singles-mode transmission data in PET. We compared our scatter correction data with the previously validated simulation data for uniform and non-uniform phantoms and for two different transmission source radionuclides. Our scatter calculation correctly predicted the contribution from scattered photons to the simulated data for all phantoms and both transmission sources. We then applied our scatter correction as part of an iterative reconstruction algorithm for simulated and experimental PET transmission data for uniform and non-uniform phantoms. We also tested our reconstruction and scatter correction procedure using transmission data for several animal studies (mice, rats and primates). For all studies considered, we found that the average reconstructed linear attenuation coefficients for water or soft-tissue regions of interest agreed with expected values to within 4%. Using a 2.2 GHz processor, the scatter correction required between 6 to 27 minutes of CPU time (without any code optimisation) depending on the phantom size and source used. This extra calculation time does not seem unreasonable considering that, without scatter corrections, errors in the reconstructed attenuation coefficients were between 18 to 45% depending on the phantom size and transmission source used.
Penerapan Buku Pribadi sebagai Upaya Pembentukan Karakter Disiplin Siswa Kelas VI B UPTD SDN Kamal 2
Creators: name: Dea Miranda, Angelina
name: Pratikno, Ahmad Sudi
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390304
subject: Primary education
classificationCode: 460105
subject: Applications in social sciences and education

description: Penelitian ini bertujuan untuk mengetahui berbagai informasi tentang penerapan buku pribadi yang diterapkan oleh pendidik pada kelas VI B UPTD SDN Kamal 2 sebagai upaya untuk membentuk karakter disiplin belajar siswa. Penelitian ini menggunakan metode deskriptif kualitatif. Teknik pengumpulan data yang digunakan adalah wawancara. Informasi mengenai penerapan buku pribadi sebagai upaya pembentukan karakter disiplin belajar siswa digali dan diperoleh melalui guru kelas VI B. Subjek penelitian adalah seluruh siswa kelas VI B. Hasil penelitian menunjukkan bahwa buku pribadi dinilai efektif untuk membentuk karakter disiplin siswa karena melatih peserta didik dalam melakukan tanggung jawabnya baik sebagai warga sekolah dan sebagai warga kelas VI B dengan menaati kesepakatan kelas yang telah dibuat.
Mobile technologies and public spaces
Creators: name: Mani, Sanaz
Publisher: name: University of British Columbia
Year: 2008

description: Mobile technologies are the latest technologies in the realm of communication media. They have the potential to flatten the world by making it a place where gender, age, class, race and nationality can no longer hold us back from being heard and being informed. We have learned that these technologies can help to liberate and empower us, and they can lead to a collective cognition as much as they can distract us from what we need to know about the world we live in. In Greece thousands of years ago, a selected number of Greeks had a public space called the Agora to discuss the issues that concerned the public, meaning each and every citizen. They were the first to be able to create the space and place were the word “democracy” could be brought into language; the very word that was used to start a new war in the era of a communication revolution in the 2003 invasion of Iraq. There are still issues that concern the public today such as wars, global warming, homelessness or human rights which are all matters of our collective cognition. However, today in an age of information revolution the public life of people and their collective cognition is being exercised mostly in the virtual spaces of the Internet. Simultaneously, some physical spaces are being abandoned by people. This thesis investigates the possibility of having physical public spaces that are enriched with communication media and not weakened by it. If architects rethink their designs based on a new understanding of the networked society it might be possible to turn this “networked individualism” into a networked collectivism. However, most designed public spaces fail to offer new possibilities that can transform space for the new generation of users. Here, the aim is to understand a new generation of users. Who have they become as a result of new communication media? And how can architects design in a way that responds to this new subject in architecture?
Parents as play date interventionists for children with autism spectrum disorders
Creators: name: Jull, Stephanie G.
Publisher: name: University of British Columbia
Year: 2008

description: Teaching children with autism to interact with their typically developing peers can be a challenge. Previous research has documented that there are many effective ways to teach social interaction; however, these interventions were implemented almost exclusively by trained professionals. The purpose of this study was to assess the effectiveness of parent-implemented contextually supported play dates. Specifically, two parents were taught to use mutual reinforcement and to design cooperative arrangements to help their child with autism to interact with a typical peer in their homes. Two independent reversal designs were used to demonstrate a functional relationship between parent-supported contextually supported play dates and an increase in synchronous reciprocal interactions for both participants. Social validity was also high for both parents; however, there was no consistent impact on participant, confederate, or parent affect. The results are discussed with reference to previous research, future directions, and implications for practice.
[Unsere Vögel]
Creators: name: Marquardt, Karl
Publisher: name: Gemeinde Horgen
Year: 1989
Subjects: subject: 500 Naturwissenschaften und Mathematik
subject: 590 Tiere (Zoologie)
subject: Horgen
subject: Heimatkunde
subject: Natur
subject: Tiere
subject: Ornithologie

description: Enthält eine Chronik der Gemeinde Horgen für 1988
MOESM2 of A systematic review of sub-microscopic Plasmodium vivax infection
Creators: name: Moreira, Clarissa
name: Abo-Shehada, Mahmoud
name: Ric Price
name: Drakeley, Chris
Publisher: name: Figshare
Year: 2015
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Computational Biology

description: Additional file 1. Studies excluded following evaluation of full text (NÂ =Â 142) according to the main reason for exclusion.
Additional file 1: Table S1. of Chemostat culture systems support diverse bacteriophage communities from human feces
Creators: name: Santiago-Rodriguez, Tasha
name: Ly, Melissa
name: Daigneault, Michelle
name: Brown, Ian
name: McDonald, Julie
name: Bonilla, Natasha
name: Vercoe, Emma
name: Pride, David
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Chemostat and fecal virome reads.
Additional file 2: Table S2. of Chemostat culture systems support diverse bacteriophage communities from human feces
Creators: name: Santiago-Rodriguez, Tasha
name: Ly, Melissa
name: Daigneault, Michelle
name: Brown, Ian
name: McDonald, Julie
name: Bonilla, Natasha
name: Vercoe, Emma
name: Pride, David
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Virome read assembly metrics.
Additional file 3: of Chemostat culture systems support diverse bacteriophage communities from human feces
Creators: name: Santiago-Rodriguez, Tasha
name: Ly, Melissa
name: Daigneault, Michelle
name: Brown, Ian
name: McDonald, Julie
name: Bonilla, Natasha
name: Vercoe, Emma
name: Pride, David
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Supplemental figures.
Additional file 1: Figure S1. of Characterization of human papillomavirus type 16 pseudovirus containing histones
Creators: name: Kim, Hyoung
name: Hye-Lim Kwag
name: Kim, Hong-Jin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Schematic diagram of heparin chromatography to separate HPV16 PsVs into fraction I, II and III. (DOCX 75 kb)
Additional file 7: Figure S7. of Characterization of human papillomavirus type 16 pseudovirus containing histones
Creators: name: Kim, Hyoung
name: Hye-Lim Kwag
name: Kim, Hong-Jin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Reacitivities of HPV16 PsVs from fraction I, II and III with H16.V5 or H16.E70 MAbs. The reactivities of fraction I PsVs were set at 100 %. The values are the mean ± SD of quadriplicate assays. (DOCX 43 kb)
Additional file 5: Figure S5. of Characterization of human papillomavirus type 16 pseudovirus containing histones
Creators: name: Kim, Hyoung
name: Hye-Lim Kwag
name: Kim, Hong-Jin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 60506 Virology
subject: Computational Biology

description: Lymphoproliferative responses following four immunizations with HPV16 PsVs from fraction I, II, or III. The mice were immunized four times with 50 ng of PsVs per dose at 2-week intervals. Mouse splenocytes were obtained 5 days after the fourth immunization. Mouse splenocytes were labeled with carboxyfluorescein succinimidyl ester (CFSE), stimulated with purified HPV16 L1 VLPs, and cultured for 4 days. The splenocytes were stained with allophycocyanin (APC)-conjugated anti-CD4 antibody (eBioscience, USA) and examined with a FACSCalibur flow cytometer (BD Bioscience, USA). To count CD4+ cells, the cells were gated according to forward and side scatter, and the upper-left segment of each graph was counted on FITC and APC scatter plots. Panel A shows the flow cytometry results for three individual mice. The value in panel B represents the mean ± SEM (n = 3). (DOCX 171 kb)
Additional file 1: of A comparative ethnobotany of Khevsureti, Samtskhe-Javakheti, Tusheti, Svaneti, and Racha-Lechkhumi, Republic of Georgia (Sakartvelo), Caucasus
Creators: name: Bussmann, Rainer
name: Narel Paniagua Zambrana
name: Sikharulidze, Shalva
name: Kikvidze, Zaal
name: Kikodze, David
name: Tchelidze, David
name: Khutsishvili, Manana
name: Batsatsashvili, Ketevan
name: Hart, Robbie
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Plants used in Georgia. (FOREST = includes all non garden areas; GARDEN = area where species are cultivated; Arm. = Armenian; Khev. = Khevsurian; Russ. = Russian; Svan. = Svanetian; Phsh. = Pshavian). (DOCX 153 kb)
Additional file 1: of Cost-effectiveness analysis of bortezomib in combination with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (VR-CAP) in patients with previously untreated mantle cell lymphoma
Creators: name: Keep, Marjolijn Van
name: Gairy, Kerry
name: Divyagiri Seshagiri
name: Pushpike Thilakarathne
name: Lee, Dawn
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: 60506 Virology

description: List of local Independent Ethics Committees and Institutional Review Boards. (DOCX 24 kb)
Teaching a child with autism to imitate in natural contexts using video modeling
Creators: name: Kleeberger, Victoria
Publisher: name: University of British Columbia
Year: 2008

description: Imitation is a core deficit often observed in children diagnosed with autism. Video modeling has been shown to be effective for teaching children with autism a variety of skills, but there is little research demonstrating the effectiveness of this technique with core skills such as imitation. The purpose of this study was to examine the effectiveness of a video modeling intervention to teach a preschool-age child with autism to imitate novel and acquired actions (with and without objects) in natural contexts (i.e., songs and toy play activities). A general case approach was used to examine the instructional universe of common preschool songs in order to select the exemplars that were most likely to facilitate generalization. In addition to video modeling, additive components that included highlighting the critical features of the video examples and prompting/fading were required to demonstrate a functional relationship. Experimental control was evident in a multiple baseline design across three imitation activities. The results are discussed with reference to previous research, future research directions, and implications for practice in educational settings.
Additional file 3: Figure S3. of Characterization of human papillomavirus type 16 pseudovirus containing histones
Creators: name: Kim, Hyoung
name: Hye-Lim Kwag
name: Kim, Hong-Jin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer

description: TEM analysis of HPV16 PsVs from fraction I, II and III. Magnification x 234,000 (bars are 50 or 100Â nm). (DOCX 1656 kb)
Additional file 4: Figure S4. of Characterization of human papillomavirus type 16 pseudovirus containing histones
Creators: name: Kim, Hyoung
name: Hye-Lim Kwag
name: Kim, Hong-Jin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology

description: PCRs for reporter genes in HPV16 PsVs from fractions I, II and III. A shows the pYSEAP contents of PsVs from fraction I, II and III. B confirms the specificity of the PCR for the relevant region of the pYSEAP construct. Buffer only and pcDNA3.1 are negative controls. To measure pYSEAP content per particle, in panel A, identical amounts of PsVs from fraction I, II, and III were used (20 ng based on L1 content). 25, 30 or 38 cycles of PCR were carried out. Thirty cycles of PCR were performed for panel B. The same primer set used in the quantitative real time PCR for amplifying the 80 bp region of pYSEAP was used (see the quantitative real time PCR section in Methods). Amplicons were analyzed on a 1.5 % agarose gel. (DOCX 406 kb)
Supporting migration and labour mobility (UNTANGLED Policy Brief)
Creators: name: Ciprikis Klavs
name: McGuinness Seamus
name: Redmond Paul
name: Martin Ludivine
name: Machado Joël
name: Verheyden Bertrand
name: Bachmann Ronald
name: Bredtmann Julia
Publisher: name: Zenodo
Year: 2024

description: Ageing of the European population, labour market shortages, and skills mismatches across the EU reinforce the need to recruit immigrant workers to meet the needs of the labour market. Project UNTANGLED’s results, together with previous literature, have important implications for migration policies at an EU and country specific level. UNTANGLED reports a relatively high level of migration to the EU and within the EU with strong differences in the education levels of migrants, and strong differences in the extent of migration between the EU countries. As the number of posted workers across the EU increases it becomes particularly important for the European Labour Authority (ELA) to safeguard the rights of migrants and establish fair labour markets across the bloc. Two key challenges that emerge in this context are the attractiveness of EU countries for migrants, and the successful integration of migrants into the labour market. The key challenges are addressed in this report by providing policy  recommendations at the EU and country level. European member states can offer financial incentives to attract migrants to the areas with the highest needs. Such incentives can take the form of reimbursement of costs when people move to take up work in another area, and preferential tax schemes to  attract high-skilled foreigners. Employment opportunities should be improved for non-EU persons seeking employment in the EU by providing residence and work permits. The European Qualifications Framework should be more strongly implemented to accelerate the recognition of occupational qualifications in the EU and enable efficient movement of labour to and within the region. Fourth, societal integration should be improved by even more strongly focusing on language learning, providing access to affordable accommodation, appropriate
Additional file 1: of Comparative effectiveness of adding weight control simultaneously or sequentially to smoking cessation quitlines: study protocol of a randomized controlled trial
Creators: name: Bush, Terry
name: Lovejoy, Jennifer
name: Javitz, Harold
name: Magnusson, Brooke
name: Alula Torres
name: Mahuna, Stacey
name: Benedict, Cody
name: Wassum, Ken
name: Spring, Bonnie
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: BQS Consentâ  mailed version. (DOCX 30 kb)
Additional file 1: Table S1. of Sensitive quantification of Clostridium perfringens in human feces by quantitative real-time PCR targeting alpha-toxin and enterotoxin genes
Creators: name: Nagpal, Ravinder
name: Kiyohito Ogata
name: Tsuji, Hirokazu
name: Matsuda, Kazunori
name: Takahashi, Takuya
name: Nomoto, Koji
name: Suzuki, Yoshio
name: Kawashima, Kazunari
name: Nagata, Satoru
name: Yamashiro, Yuichiro
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Standard curve information. (PDF 13 kb)
MOESM1 of Rationale and design of the randomised controlled trial to assess the impact of liraglutide on cardiac function and structure in young adults with type 2 diabetes (the LYDIA study)
Creators: name: Z. Htike
name: T. Yates
name: E. Brady
name: D. Webb
name: L. Gray
name: D. Swarbrick
name: G. McCann
name: K. Khunti
name: M. Davies
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Additional file 1. Appendices.
Functional analysis of murine CD43 shedding : a role for the CD43 cytoplasmic tail in nuclear signalling
Creators: name: Seo, Wooseok
Publisher: name: University of British Columbia
Year: 2008

description: CD43, a representative of the leukocyte mucin family proteins, is a transmembrane protein highly expressed on most lymphohemopoietic cells and is believed to play a role in the regulation of leukocyte activation and/or migration. CD43 was shown to be proteolytically shed from human cells and high concentrations of soluble CD43 have been found in human plasma. The biological significance of CD43 shedding however remains enigmatic. To study the functional significance of CD43 shedding, we initiated our study by investigating whether CD43 shedding also occurs in the murine system and confirmed using flow cytometry, Western blot and ELISA techniques that murine CD43 is cleaved from the cell surface as is observed in the human system. To examine the biological significance of CD43 shedding, we designed and constructed non-sheddable forms of murine CD43. Ectopic expression of non-sheddable CD43 molecules in primary CD43 deficient bone marrow cells showed that these CD43 mutants have serious negative impacts on cell viability, revealing CD43 shedding as an essential process and implying that the CD43 mutants interfered with intracellular signaling processes. Our data support the hypothesis that CD43 ectodomain shedding is a requirement for release of the cytoplasmic domain and its translocation to the nucleus. In support of our hypothesis, we confirmed that the CD43 cytoplasmic domain is localized in the nucleus and is modified by SUMO (small ubiquitin-like modifier) peptides. In an attempt to determine the functional significance of CD43 nuclear translocation and SUMO modification, we examined nuclei from hemopoietic cells more closely and observed that the CD43 cytoplasmic tail is localized in a subnuclear structure called promyelocytic nuclear bodies, which control many nuclear functions including apoptosis. Consistent with this observation we find that leukocytes from CD43 deficient mice have an increased apoptotic response upon growth factor withdrawal. We conclude that nuclear translocation of the CD43 cytoplasmic tail serves to control the apoptotic response in leukocytes and that CD43 functions as an anti-apoptotic molecule.
Additional file 1: of Efficacy of brief behavioral counselling by allied health professionals to promote physical activity in people with peripheral arterial disease (BIPP): study protocol for a multi-center randomized controlled trial
Creators: name: Burton, Nicola
name: Zanfina Ademi
name: Best, Stuart
name: Singh, Maria Fiatarone
name: Jenkins, Jason
name: Lawson, Kenny
name: Leicht, Anthony
name: Yorgi Mavros
name: Noble, Yian
name: Norman, Paul
name: Norman, Richard
name: Parmenter, Belinda
name: Pinchbeck, Jenna
name: Reid, Christopher
name: Rowbotham, Sophie
name: Yip, Lisan
name: Golledge, Jonathan
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: PAD Information Sheet. (PDF 240Â kb)
Additional file 2: Figure S1. of The global pendulum swing towards community health workers in low- and middle-income countries: a scoping review of trends, geographical distribution and programmatic orientations, 2005 to 2014
Creators: name: Schneider, Helen
name: Dickson Okello
name: Lehmann, Uta
Publisher: name: Figshare
Year: 2016
Subjects: Medicine
Molecular Biology
Science Policy
Computational Biology

description: Distribution of publications by region and country. (DOCX 15 kb)
Additional file 1: Table S1. of Systemic inflammation in a melanoma patient treated with immune checkpoint inhibitorsâ  an autopsy study
Creators: name: Koelzer, Viktor
name: Rothschild, Sacha
name: Zihler, Deborah
name: Wicki, Andreas
name: Berenika Willi
name: Willi, Niels
name: MichĂ¨Le Voegeli
name: Cathomas, Gieri
name: Zippelius, Alfred
name: Mertz, Kirsten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer

description: Laboratory studies. Data on differential blood counts, renal function, liver function tests and thyroid function during each treatment cycle (dacarbazine, ipilimumab, nivolumab) are provided. (DOCX 16 kb)
An investigation into the genes mediating myoblast migration in the nematode : Caenorhabditis elegans
Creators: name: Viveiros, Ryan
Publisher: name: University of British Columbia
Year: 2008

description: During C. elegans embryogenesis, myoblasts initially form two rows along the left and right lateral midlines and at ~290 min of development migrate dorsally and ventrally to form the four muscle quadrants present upon hatching (Sulston et al, 1983). As the myoblasts migrate they are still dividing, as are many other cells in their immediate environment. This means the cell-cell contact of cells during migration is dynamic and can vary from animal to animal (Schnabel et al, 1997). This situation creates an environment where the extracellular matrix (ECM) and cell surface contacts are in constant flux, which begs the questions as to how these cells navigate unerringly to their final destination. In an attempt to identify genes mediating these migrations, I performed an RNAi based screen targeting 776 genes predicted to be members of the extracellular matrix (ECM), or one of its receptors. Using both feeding and injection based RNAi, I was able to identify three genes of interest. Knockdowns of F56B3.2 resulted in paralyzed animals with detached muscle, making it a good candidate for a new component of the muscle attachment complex. F33G12.4 knockdowns resulted in an embryonic arrest phenotype with an abnormal muscle lineage, possibly stemming from polarity defects. The only knockdown that resulted in muscle migration defects was that for lam-2, which encodes for the laminin gamma subunit. Analysis of the lam-2 knockdown, as well as knockdowns for the other laminin subunits, revealed dorsal/ventral migration defects as well as a posterior displacement of the anterior-most ventral muscle cells. Investigation of this posterior displacement has led to the identification of a previously un-described anterior muscle migration event and its dependency upon the extension of muscle processes from the leading cells.
MOESM2 of Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012
Creators: name: Zhiyong Zhou
name: Mitchell, Rebecca
name: Kariuki, Simon
name: Odero, Christopher
name: Otieno, Peter
name: Kephas Otieno
name: Onyona, Philip
name: Were, Vincent
name: Wiegand, Ryan
name: Gimnig, John
name: Walker, Edward
name: Meghna Desai
name: Shi, Ya
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cancer
subject: Computational Biology

description: Additional file 2. Proportion of parasite and gametocyte presence in 996 samples tested by 18S-and Pfs25-NASBA stratified by risk factor and intervention. Proportions are reported in overall and each area, $NA: not analysed because parasitaemia causes anaemia.
Additional file 1: Table S1. of Gene expression and metabolism preceding soft scald, a chilling injury of ‘Honeycrisp’ apple fruit
Creators: name: Leisso, Rachel
name: Gapper, Nigel
name: Mattheis, James
name: Sullivan, Nathanael
name: Watkins, Christopher
name: Giovannoni, James
name: Schaffer, Robert
name: Johnston, Jason
name: Hanrahan, Ines
name: Hertog, Maarten
name: Nicolaï, Bart
name: Rudell, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 60506 Virology

description: Quality and maturity of fruit from ‘Honeycrisp’ orchards used for the metabolomic (all orchards) and transcriptomic (orchards A_H1, A_H2, A_H3, M, and P) analyses. (DOCX 34 kb)
Additional file 1: Table S1. of The global pendulum swing towards community health workers in low- and middle-income countries: a scoping review of trends, geographical distribution and programmatic orientations, 2005 to 2014
Creators: name: Schneider, Helen
name: Dickson Okello
name: Lehmann, Uta
Publisher: name: Figshare
Year: 2016
Subjects: Medicine
Science Policy
Computational Biology

description: Coding of papers by theme. (DOCX 16 kb)
Additional file 1: of Potential for task-sharing to Lady Health Workers for identification and emergency management of pre-eclampsia at community level in Pakistan
Creators: name: Salam, Rehana
name: Rahat Qureshi
name: Sheikh, Sana
name: Khowaja, Asif
name: Sawchuck, Diane
name: Vidler, Marianne
name: Dadelszen, Peter Von
name: Shujaat Zaidi
name: Bhutta, Zulfiqar
Publisher: name: Figshare
Year: 2016
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy

description: Reviewer reports. (PDF 158Â kb)
Additional file 6: Figure S6. of Two maternal duplications involving the CDKN1C gene are associated with contrasting growth phenotypes
Creators: name: Boonen, Susanne
name: Freschi, Andrea
name: Christensen, Rikke
name: Valente, Federica
name: Lildballe, Dorte
name: Perone, Lucia
name: Palumbo, Orazio
name: Carella, Massimo
name: Uldbjerg, Niels
name: Sparago, Angela
name: Riccio, Andrea
name: Cerrato, Flavia
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology

description: DNA methylation (top) and copy number (CN, bottom) analyses at 11p15 region in family 2, determined by MS-MLPA. The histograms represent the normalized DNA methylation of ICR1 and ICR2 and CN of the genomic region spanning from the NSD1 to KCNQ1 gene. The CN range that is considered normal is shadowed. Note that methylation of ICR2 is abnormally low while CN values of ICR2 and KCNQ1 exon 13-17 are abnormally high in the proband and his mother. (PDF 130Â kb)
Patient perspectives on health care system navigation : the chronic illness multi-morbidity experience
Creators: name: Ravenscroft, Eleanor Fay
Publisher: name: University of British Columbia
Year: 2008

description: Meeting the health care needs of people with chronic conditions presents one of the greatest challenges for 21st century health care system renewal. Appropriate redesign of health care delivery with this complex patient population in mind requires information from many sources. Although much is known about the patient experience of chronic illness much less is understood about how patients navigate their health care delivery context. The purpose of this qualitative study was to examine the point of view of patients dealing with multi-morbidity. These people have a unique understanding of how health care delivery links across time, place, and settings because of the care they require for their multiple chronic conditions. An interpretive descriptive design was used to examine patient navigation from the perspective of 20 adult patients with chronic kidney disease, and co-existing diagnoses of diabetes mellitus and/or cardiovascular disease. The findings generated from iterative, constant comparative analysis add important patient perspectives about health care system navigation. From the consumer perspective health care navigation is challenging, requiring (a) ongoing discovery about the complex social structures that make up the health care system, and (b) learning how to strategically use this knowledge to manage the health care system. The findings highlight the disjunctures and misalignments in the health care delivery system, the cumulative health care-related burden of multiple chronic conditions for consumers, and consumer concerns about subtle inequities in the health care system. As health care renewal efforts gain momentum new knowledge from the perspective of consumers, such as that captured in this research, is important. The consumer perspective provides a valuable opportunity for stakeholders in health care policy- and decision-making to contextualize and make greater sense of the information used in making decisions about health care service delivery for vulnerable populations, like patients with multiple chronic conditions.
MOESM1 of Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012
Creators: name: Zhiyong Zhou
name: Mitchell, Rebecca
name: Kariuki, Simon
name: Odero, Christopher
name: Otieno, Peter
name: Kephas Otieno
name: Onyona, Philip
name: Were, Vincent
name: Wiegand, Ryan
name: Gimnig, John
name: Walker, Edward
name: Meghna Desai
name: Shi, Ya
Publisher: name: Figshare
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Density distribution of parasites and gametocytes detected by 2 molecular assays. Histograms of parasite and gametocyte densities in age groups as quantified by molecular methods (18S-NASBA in Panel A and Pfs25-NASBA in Panel B). Histogram with filled grey bars represents smear-negative samples, while histogram with open bars represents smear-positive samples. X-axes represent the density of parasite (Panel A) or gametocytes (Panel B) per microliter of blood. Y-axes represents the number of positive individuals by molecular assays.
Additional file 4: Figure S3. of Gene expression and metabolism preceding soft scald, a chilling injury of ‘Honeycrisp’ apple fruit
Creators: name: Leisso, Rachel
name: Gapper, Nigel
name: Mattheis, James
name: Sullivan, Nathanael
name: Watkins, Christopher
name: Giovannoni, James
name: Schaffer, Robert
name: Johnston, Jason
name: Hanrahan, Ines
name: Hertog, Maarten
name: Nicolaï, Bart
name: Rudell, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 60506 Virology
subject: Computational Biology

description: Subtractive (high risk – low risk) correlation network of highly correlated expressed genes and metabolites. (DOCX 373 kb)
Additional file 4: of Non-technical skills evaluation in the critical care air ambulance environment: introduction of an adapted rating instrument - an observational study
Creators: name: Myers, Julia
name: Powell, David
name: Psirides, Alex
name: Hathaway, Karyn
name: Aldington, Sarah
name: Haney, Michael
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Behavioural descriptor modifications based on content evaluation survey. (PDF 259 kb)
Additional file 1: of Non-technical skills evaluation in the critical care air ambulance environment: introduction of an adapted rating instrument - an observational study
Creators: name: Myers, Julia
name: Powell, David
name: Psirides, Alex
name: Hathaway, Karyn
name: Aldington, Sarah
name: Haney, Michael
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Literature search results. (PDF 342 kb)
Additional file 4: of Benchmarking of de novo assembly algorithms for Nanopore data reveals optimal performance of OLC approaches
Creators: name: Yesesri Cherukuri
name: Sarath Chandra Janga
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Overview of the influence of memory allocation on the running times for various assemblers. (PDF 155Â kb)
Additional file 3: Table S2. of The global pendulum swing towards community health workers in low- and middle-income countries: a scoping review of trends, geographical distribution and programmatic orientations, 2005 to 2014
Creators: name: Schneider, Helen
name: Dickson Okello
name: Lehmann, Uta
Publisher: name: Figshare
Year: 2016
Subjects: Medicine
Molecular Biology
Science Policy
Computational Biology

description: Distribution of publications by region, country and programmatic focus. (DOCX 77 kb)
Additional file 1: Figure S1. of Two maternal duplications involving the CDKN1C gene are associated with contrasting growth phenotypes
Creators: name: Boonen, Susanne
name: Freschi, Andrea
name: Christensen, Rikke
name: Valente, Federica
name: Lildballe, Dorte
name: Perone, Lucia
name: Palumbo, Orazio
name: Carella, Massimo
name: Uldbjerg, Niels
name: Sparago, Angela
name: Riccio, Andrea
name: Cerrato, Flavia
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Evolutionary Biology
subject: Developmental Biology
subject: Marine Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Comparative genomic hybridization analysis performed on DNA of the proband from family 1. The extension, the genomic localization (GRC h37/hg19) and the genes included in the duplication are shown. (PDF 54Â kb)
Additional file 1: Table S1. of Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour
Creators: name: Huang, Katie
name: Mikeska, Thomas
name: Li, Jason
name: Takano, Elena
name: Millar, Ewan
name: Graham, Peter
name: Boyle, Samantha
name: Campbell, Ian
name: Speed, Terence
name: Dobrovic, Alexander
name: Fox, Stephen
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Comparison of DNA methylation frequency of genes screened in breast carcinomas with the methylation frequency in literature. (DOCX 100 kb)
Additional file 3: Figure S2. of Gene expression and metabolism preceding soft scald, a chilling injury of ‘Honeycrisp’ apple fruit
Creators: name: Leisso, Rachel
name: Gapper, Nigel
name: Mattheis, James
name: Sullivan, Nathanael
name: Watkins, Christopher
name: Giovannoni, James
name: Schaffer, Robert
name: Johnston, Jason
name: Hanrahan, Ines
name: Hertog, Maarten
name: Nicolaï, Bart
name: Rudell, David
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 60506 Virology

description: Up-regulated differentially expressed genes common among 0 W (at harvest), 2 W (2 weeks), and ASCA results for fruit from low risk and high risk orchards. (DOCX 272 kb)