cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of some root leachates and dry extracts of Brassicaceae plants on potato cyst nematode populations
Creators: name: Skibowska, Barbara
name: Mirosław Nowakowski
name: Nowakowski, Mateusz Maciej
name: Gryń, Grzegorz
name: Franke, Katarzyna
Publisher: name: Russian Journal of Nematology
Year: 2019
Subjects: biocontrol
Globodera rostochiensis
nematode control
nematode hatching
root leachate

description: The potential effect of Brassica plants for control of the potato cyst nematode, Globodera rostochiensis, was assessed in a laboratory experiment and pot test. Second-stage juveniles (J2) hatching in the absence of a host plant could reduce levels of G. rostochiensis populations in the field. The effect of several Brassicaceae plant extracts and root leachates on hatching of G. rostochiensis invasive J2 was tested in laboratory conditions. Raphanus sativus, Sinapis alba and Lepidium sativum were tested. The controls consisted of root leachates obtained from Solanum lycopersicum and S. tuberosum, plus leachate from pots without plants and tap water. Host plant leachates stimulated the greatest hatch (over 95%). Among the non-host plants studied, the highest hatch stimulation was with root leachate from L. sativum (53.3%). Large variation in hatching was found for cultivars of R. sativus (20.8% and 33.6%). In the pot experiment, the objective was to determine the inhibitory effect of dry matter extracts from six plants, added to the soil, on the development of the G. rostochiensis population in the cultivation of a susceptible potato cultivar ‘Desiree’. Two R. sativus cultivars (‘Colonel’ and ‘Romesa’), two S. alba cultivars (‘Bardena’ and ‘Concerta’), L. sativum and Nasturtium officinale were chosen for the tests. No extract was used for the negative control, and for the positive control, Vydate® 10G nematicide was added. Among the extracts studied, L. sativum extract limited development of the nematode population (75%) closest to the chemical treatment.
Sonnenfleckenzeichnung Nr. 87.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.04.2010, 06:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
A Systematic Literature Review of Animal-Assisted Interventions in Oncology (Part I): Methods and Results
Creators: name: Roberts, D.L.
name: Somers, T.
name: Holder, T.R.N.
name: Gruen, M.E.
name: Bozkurt, A.
Publisher: name: SAGE Publications Inc.
Year: 2020

description: Animal-assisted interventions (AAIs) use human-animal interactions to positive effect in various contexts including cancer care. As the first installment of a 2-part series, this systematic literature review focuses on the research methods and quantitative results of AAI studies in oncology. We find methodological consistency in the use of canines as therapy animals, in the types of high-risk patients excluded from studies, and in the infection precautions taken with therapy animals throughout cancer wards. The investigated patient endpoints are not significantly affected by AAI, with the exceptions of improvements in oxygen consumption, quality of life, depression, mood, and satisfaction with therapy. The AAI field in oncology has progressed significantly since its inception and has great potential to positively affect future patient outcomes. To advance the field, future research should consistently improve the methodological design of studies, report data more completely, and focus more on the therapy animal’s well-being.
Sonnenfleckenzeichnung Nr. 263.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.11.2010, 09:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Ultrastructural observation of spermatogenesis in the free-living marine nematode Parodontophora marisjaponici (Nematoda: Araeolaimida: Axonolaimidae)
Creators: name: Gliznutsa, Lyubov A.
name: Yushin, Vladimir V.
Publisher: name: Russian Journal of Nematology
Year: 2019
Subjects: Axonolaimus arcuatus
centrioles
fibrous bodies
Halalaimus dimorphus
membranous organelles
pseudopod
sperm pattern

description: Spermatogenesis in Parodontophora marisjaponici, described using TEM, is similar in basic features to that of the rhabditid nematodes. Sperm development includes formation of complexes of fibrous bodies (FB) and membranous organelles (MO), which appear in spermatocytes; the complexes dissociate in the spermatids; the immature sperm contains separate FB and MO; the mature spermatozoa are bipolar cells subdivided into pseudopod and a main cell body containing a nucleus without a nuclear envelope, and peripheral mitochondria and MO. However, P. marisjaponici has distinct peculiarities in morphology and differentiation of male gametes: i) tripartite FB-MO complexes that include mitochondria; and ii) fusion of initially separate MO into one giant cistern that in the mature spermatozoa opens to exterior via multiple pores. This type of sperm development and structure constitute the new pattern that is proposed as an apomorphy of the araeolaimid family Axonolaimidae. The study of spermatogenesis in other families inside the order Araeolaimida such as Comesomatidae will be fruitful for further analysis of sperm diversity in nematodes.
Views of advance care planning in older hospitalized patients following an emergency admission: A qualitative study.
Creators: name: Bielinska, Anna-Maria
name: Soosaipillai, Gehan
name: Riley, Julia
name: Darzi, Ara
name: Urch, Catherine
name: Archer, Stephanie
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: subject: Research Article
subject: Medicine and health sciences
subject: People and places
subject: Social sciences
subject: FOS: Social sciences
subject: Research and analysis methods

description: Funder: NIHR Imperial Biomedical Research Centre; funder-id: http://dx.doi.org/10.13039/501100013342
description: BACKGROUND: There is increasing evidence of the need to consider advance care planning (ACP) for older adults who have been recently admitted to hospital as an emergency. However, there is a gap in knowledge regarding how to facilitate ACP following acute illness in later life. AIM/OBJECTIVES: To explore the perceived impact of ACP on the lives of older persons aged 70+ who have been acutely admitted to hospital. METHOD: Semi-structured qualitative interviews were conducted with older adults aged 70+ who were admitted to hospital as an emergency. Thematic analysis was enhanced by dual coding and exploration of divergent views within an interdisciplinary team. RESULTS: Twenty participants were interviewed. Thematic analysis generated the following themes: (1) Bespoke planning to holistically support a sense of self, (2) ACP as a socio-cultural phenomenon advocating for older persons rights, (3) The role of personal relationships, (4) Navigating unfamiliar territory and (5) Harnessing resources. CONCLUSION: These findings indicate that maintaining a sense of personal identity and protecting individuals' wishes and rights during ACP is important to older adults who have been acutely unwell. Following emergency hospitalization, older persons believe that ACP must be supported by a network of relationships and resources, improving the likelihood of adequate preparation to navigate the uncertainties of future care in later life. Therefore, emergency hospitalization in later life, and the uncertainty that may follow, may provide a catalyst for patients, carers and healthcare professionals to leverage existing or create new relationships and target resources to enable ACP, in order to uphold older persons' identity, rights and wishes following acute illness.
A Systematic Literature Review of Animal-Assisted Interventions in Oncology (Part II): Theoretical Mechanisms and Frameworks
Creators: name: Bozkurt, A.
name: Holder, T.R.N.
name: Somers, T.
name: Roberts, D.L.
name: Gruen, M.E.
Publisher: name: SAGE Publications Inc.
Year: 2020

description: Animal-assisted interventions (AAIs) can improve patients’ quality of life as complementary medical treatments. Part I of this 2-paper systematic review focused on the methods and results of cancer-related AAIs; Part II discusses the theories of the field’s investigators. Researchers cite animal personality, physical touch, physical movement, distraction, and increased human interaction as sources of observed positive outcomes. These mechanisms then group under theoretical frameworks such as the social support hypothesis or the human-animal bond concept to fully explain AAI in oncology. The cognitive activation theory of stress, the science of unitary human beings, and the self-object hypothesis are additional frameworks mentioned by some researchers. We also discuss concepts of neurobiological transduction connecting mechanisms to AAI benefits. Future researchers should base study design on theories with testable hypotheses and use consistent terminology to report results. This review aids progress toward a unified theoretical framework and toward more holistic cancer treatments.
Media Studies and the Pitfalls of Publicity
Creators: name: Marwick, Alice E.
Publisher: name: SAGE Publications Inc.
Year: 2020

description: For many academics, using social media has both drawbacks and advantages. Social media may allow connection with colleagues, scholarly promotion, and public engagement, and may also open researchers up to criticism and even possible harassment. This essay argues that we must think critically about logics of self-branding and attention-seeking given these two sides of the coin of social media publicity. First, publicity can easily be weaponized against scholars engaging in projects that may be socially or politically controversial by individuals or organizations who disagree with their premises. Universities are often unprepared to deal with this negative publicity and fail to protect researchers from the consequence. Second, self-branding may undermine one’s ability to be viewed as a serious scholar and requires rigorous self-censorship, particularly for those far from the white, male ideal of the professoriate. I conclude with some recommendations for academic social media use at different career stages.
Marine phosphate availability and the chemical origins of life on Earth.
Creators: name: Brady, Matthew P
name: Tostevin, Rosalie
name: Tosca, Nicholas J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/704/47/4112
/639/638/904
/639/638/169
/704/445/209
/128
/129
/145
article

description: Prebiotic systems chemistry suggests that high phosphate concentrations were necessary to synthesise molecular building blocks and sustain primitive cellular systems. However, current understanding of mineral solubility predicts negligible phosphate concentrations for most natural waters, yet the role of Fe2+, ubiquitous on early Earth, is poorly quantified. Here we determine the solubility of Fe(II)-phosphate in synthetic seawater as a function of pH and ionic strength, integrate these observations into a thermodynamic model that predicts phosphate concentrations across a range of aquatic conditions, and validate these predictions against modern anoxic sediment pore waters. Experiments and models show that Fe2+ significantly increases the solubility of all phosphate minerals in anoxic systems, suggesting that Hadean and Archean seawater featured phosphate concentrations ~103-104 times higher than currently estimated. This suggests that seawater readily met the phosphorus requirements of emergent cellular systems and early microbial life, perhaps fueling primary production during the advent of oxygenic photosynthesis.
(502312) Victor Green
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(502313) Lizzie Green
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 51.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.03.2010, 08:15, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 233.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.10.2010, 08:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502315) Henry Bloomer
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Fractionation by shape in deterministic lateral displacement microfluidic devices
Creators: name: Jiang, Mingliang
name: Budzan, Kostyantyn
name: Drazer, German
Publisher: name: arXiv
Year: 2014
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We investigate the migration of particles of different geometrical shapes and sizes in a scaled-up model of a gravity-driven deterministic lateral displacement (g-DLD) device. Specifically, particles move through a square array of cylindrical posts as they settle under the action of gravity. We performed experiments that cover a broad range of orientations of the driving force (gravity) with respect to the columns (or rows) in the square array of posts. We observe that as the forcing angle increases particles initially locked to move parallel to the columns in the array begin to move across the columns of obstacles and migrate at angles different from zero. We measure the probability that a particle would move across a column of obstacles, and define the critical angle θc as the forcing angle at which this probability is 1/2. We show that critical angle depends both on particle size and shape, thus enabling both size- and shape-based separations. Finally, we show that using the diameter of the inscribed sphere as the characteristic size of the particles the corresponding critical angle becomes independent of particle shape and the relationship between them is linear. This linear and possibly universal behavior of the critical angle as a function of the diameter of the inscribed sphere could provide guidance in the design and optimization of g-DLD devices used for shape-based separation.
Sonnenfleckenzeichnung Nr. 68.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.03.2010, 08:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 182.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.08.2010, 10:00, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Data for: Off-host survival of blacklegged ticks in eastern North America: A multi-stage, multi-year, and multi-site study
Creators: name: Brunner, Jesse
name: Ostfeld, Richard
name: LaDeau, Shannon
name: Valentine, Elizabeth
name: Schierer, Megan
name: Killilea, Mary
Publisher: name: Zenodo
Year: 2022
Subjects: Ixodes scapularis
Vector biology
daily air temperatures
vapor pressure deficit
survivorship
molt timing

description: Climatic conditions are widely thought to govern the distribution and abundance of ectoparasites, such as the blacklegged tick (Ixodes scapularis), vector of the agents of Lyme disease and other emerging human pathogens. However, translating physiological tolerances to distributional limits or mortality is challenging. Ticks may be able to avoid or tolerate unsuitable conditions, and what is lethal to one life history stage may not extend to others. Thus, even after decades of research there are clear gaps in our knowledge about how climatic conditions determine tick distributions or patterns of abundance. We present the results of a comprehensive, three-year study of the influence of local temperatures and vapor pressure deficits on the survival of each free-living, off-host stage of I. scapularis in semi-natural enclosures across three locations that span their current distribution in eastern North America. We found that only larvae are clearly sensitive to direct mortality from climatic conditions, specifically desiccating conditions, whereas mortality of nymphs and adults appears to stem from exhausted energy reserves. We also found strong evidence that key developmental transitions in the tick's life cycle—fed larvae molting into to nymphs, fed nymphs molting into adults, and fed females producing larvae (via egg masses)—were all strongly temperature-dependent, though temperatures were not limiting in any of our sites. Collectively, our results suggest that climate is likely to impact I. scapularis largely through its impact on the larval stage.
description: Data are in Excel format (xlsx or csv file types). Scripts are written in Rmd files and require an instalation of Rstan.Funding provided by: U.S. Department of Defense
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000005
Award Number: Strategic Environmental Research and Development Program (SERDP) grant 16 RC01-031/RC-2637
description: Primary data consists of known numbers of ticks of a given life stage deployed in soil core enclosures (SCEs) and then the number recovered alive at a later date. This includes all flat (unfed) tick life stages as well as recently fed ticks molting (fed larvae and fed nymphs) or producing offspring (fed adults). These survivorship and life history transition data are paired with data on the daily ambient conditions (temperature and vapor pressure deficit) averaged across the roughly hourly readings of numerous iButton data loggers.
Sonnenfleckenzeichnung Nr. 283.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.12.2010, 08:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Enhanced ocean oxygenation during Cenozoic warm periods.
Creators: name: Auderset, Alexandra
name: Moretti, Simone
name: Taphorn, Björn
name: Ebner, Pia-Rebecca
name: Kast, Emma
name: Wang, Xingchen T
name: Schiebel, Ralf
name: Sigman, Daniel M
name: Haug, Gerald H
name: Martínez-García, Alfredo
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/704/106/47
/704/106/2738
/704/106/413
article

description: Dissolved oxygen (O2) is essential for most ocean ecosystems, fuelling organisms' respiration and facilitating the cycling of carbon and nutrients. Oxygen measurements have been interpreted to indicate that the ocean's oxygen-deficient zones (ODZs) are expanding under global warming1,2. However, models provide an unclear picture of future ODZ change in both the near term and the long term3-6. The paleoclimate record can help explore the possible range of ODZ changes in warmer-than-modern periods. Here we use foraminifera-bound nitrogen (N) isotopes to show that water-column denitrification in the eastern tropical North Pacific was greatly reduced during the Middle Miocene Climatic Optimum (MMCO) and the Early Eocene Climatic Optimum (EECO). Because denitrification is restricted to oxygen-poor waters, our results indicate that, in these two Cenozoic periods of sustained warmth, ODZs were contracted, not expanded. ODZ contraction may have arisen from a decrease in upwelling-fuelled biological productivity in the tropical Pacific, which would have reduced oxygen demand in the subsurface. Alternatively, invigoration of deep-water ventilation by the Southern Ocean may have weakened the ocean's 'biological carbon pump', which would have increased deep-ocean oxygen. The mechanism at play would have determined whether the ODZ contractions occurred in step with the warming or took centuries or millennia to develop. Thus, although our results from the Cenozoic do not necessarily apply to the near-term future, they might imply that global warming may eventually cause ODZ contraction.
Sonnenfleckenzeichnung Nr. 138.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.06.2010, 06:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502317) George William Lax
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Modelling waves and currents in muddy coastal areas, with a focus on the Suriname coastal zone
Creators: name: Tzampazidou, Maria Eirini
name: Swart, Huib De
name: Smits, Bob
name: Nnafie, Abdel
name: Vries, Job De
name: Jong, Steven De
Publisher: name: figshare
Year: 2020
Subjects: subject: Oceanography
subject: FOS: Earth and related environmental sciences
subject: Physical Geography
subject: 49999 Earth Sciences not elsewhere classified

description: The mud banks in front of the coast of Suriname are an important coastal feature and play a key role in coastal evolution by governing the flow and wave characteristics. Suriname is located in the center of the Guiana basin and it is characterized by its muddy coast. The Amazon river is supplying the Guiana basin with about 7 to 10 E8 tons of sediment every year, leading to the formation of long mud banks that migrate along its coasts. This study aims at applying the SWAN-Mud and Del‰3D-FLOW model to evaluate the hydrodynamics and morphology of the Suriname coast by assessing wave periods, wave height, ocean currents and dissipation of wave energy arriving at the coast. Technical modelling problems and data availability restricted the running of scenarios using the model. Further model studies are required to understand the dissipation of wave energy by the mud banks and the effects on erosion and accretion of the Suriname coast.
Sonnenfleckenzeichnung Nr. 190.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.08.2010, 08:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Pleomorphic Invasive Lobular Carcinoma of the Breast With Extracellular Mucin and HER2 Amplification
Creators: name: Burky, M.J.
name: Calhoun, B.C.
name: Ray, E.M.
name: Ollila, D.W.
name: O'Connor, S.M.
name: Hertel, J.D.
Publisher: name: SAGE Publications Inc.
Year: 2020

description: Invasive lobular carcinoma with extracellular mucin is an uncommon pattern of invasive breast carcinoma. The 5th Edition of the World Health Organization Classification of Breast Tumors states that it is unknown whether these tumors are a subtype of mucinous carcinoma or invasive lobular carcinoma. Invasive lobular carcinoma with extracellular mucin frequently presents as a palpable mass and may be more likely to be grade 2 to 3 and HER2-positive than classic invasive lobular carcinoma. This case of pleomorphic invasive lobular carcinoma with extracellular mucin was detected by imaging only and was HER2-amplified, suggesting that a subset of these tumors may be clinically occult with an aggressive phenotype. Invasive lobular carcinoma with extracellular mucin is infrequently encountered and awareness of this entity is helpful in avoiding misdiagnosis.
Sonnenfleckenzeichnung Nr. 134.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.06.2010, 06:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 1.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Significance of the Genomic Landscape of a De Novo Endocrine-Resistant Metastatic Hormone Receptor–Positive Breast Cancer
Creators: name: Gandhi, S.
name: Abdou, Y.
name: Sarma, M.
name: Dhakal, A.
Publisher: name: SAGE Publications Ltd
Year: 2020

description: Endocrine therapy with or without CDK4/6 inhibitors is the most commonly used frontline treatment option for metastatic hormone receptor–positive breast cancer. Approximately, 25% to 30% of women may have resistance to endocrine therapy, especially in the setting of certain genomic mutations in the tumor. This prompts the need to identify those patients who may benefit from frontline chemotherapy over endocrine therapy. Here, we present a case of a patient who presented with a de novo metastatic hormone receptor–positive breast cancer with visceral involvement (including bone marrow) as well as multiple somatic genomic alterations. The patient was treated with upfront chemotherapy, resulting in clinical and radiographic response, but rapidly progressed when she was transitioned to hormonal therapy. This report focuses on the role of upfront chemotherapy in the setting of visceral crisis including bone marrow involvement, the role of genomic alterations in contributing to endocrine resistance, and the need for biomarker-driven treatment options for hormone receptor–positive breast cancer.
A compendium of 32,277 metagenome-assembled genomes and over 80 million genes from the early-life human gut microbiome.
Creators: name: Zeng, Shuqin
name: Patangia, Dhrati
name: Almeida, Alexandre
name: Zhou, Zhemin
name: Mu, Dezhi
name: Paul Ross, R
name: Stanton, Catherine
name: Wang, Shaopu
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/326/2565/2142
/631/326/2565/2134
/45/23
article

description: Age-specific reference genomes of the human gut microbiome can provide higher resolution for metagenomic analyses including taxonomic classification, strain-level genomic investigation and functional characterization. We present the Early-Life Gut Genomes (ELGG) catalog with 32,277 genomes representing 2172 species from 6122 fecal metagenomes collected from children under 3 years old spanning delivery mode, gestational age, feeding pattern, and geography. The ELGG substantially expanded the phylogenetic diversity by 38% over the isolate microbial genomes, and the genomic landscape of the early-life microbiome by increasing recruitment of metagenomic reads to 82.8%. More than 60% of the ELGG species lack an isolate representative. The conspecific genomes of the most abundant species from children differed in gene diversity and functions compared to adults. The ELGG genomes encode over 80 million protein sequences, forming the Early-Life Gut Proteins (ELGP) catalog with over four million protein clusters, 29.5% of which lacked functional annotations. The ELGG and ELGP references provided new insights into the early-life human gut microbiome and will facilitate studies to understand the development and mechanisms of disturbances of the human gut microbiome in early life.
title: Anforderungen der Forschungsförderer ans FDM
Creators: name: Rathmann, Torsten
Publisher: name: University of Wuppertal
Year: 2020

description: Post-print version of a journal article that was first published in: ProLibris 2018, 23(2), 64-65. Secondary publication with friendly permission of the publisher.
description: Postprint-Version eines Zeitschriftenaufsatzes, der zuerst veröffentlicht wurde in: ProLibris 2018, 23(2), 64-65. Zweitveröffentlichung mit freundlicher Genehmigung der Herausgeber.
description: ProLibris 2018, 23(2), 64-65
Some operator Bellman type inequalities
Creators: name: Bakherad, Mojtaba
name: Morassaei, Ali
Publisher: name: arXiv
Year: 2015
Subjects: subject: Functional Analysis (math.FA)
subject: Operator Algebras (math.OA)
subject: FOS: Mathematics
subject: 47A63

description: In this paper, we employ the Mond--Pečarić method to establish some reverses of the operator Bellman inequality under certain conditions. In particular, we show \begin{equation*} δI_{\mathscr K}+\sum_{j=1}^nω_jΦ_j\left((I_{\mathscr H}-A_j)^{p}\right)\ge \left(\sum_{j=1}^nω_jΦ_j(I_{\mathscr H}-A_j)\right)^{p} \,, \end{equation*} where $A_j\,\,(1\leq j\leq n)$ are self-adjoint contraction operators with $0\leq mI_{\mathscr H}\le A_j \le MI_{\mathscr H}$, $Φ_j$ are unital positive linear maps on ${\mathbb B}({\mathscr H})$, $ω_j\in\mathbb R_+ \,\,(1\leq j\leq n)$, $0 < p < 1$ and $δ=(1-p)\left(\frac{1}{p}\frac{(1-m)^p-(1-M)^p}{M-m}\right)^{\frac{p}{p-1}}+\frac{(1-M)(1-m)^p-(1-m)(1-M)^p}{M-m}$ . We also present some refinements of the operator Bellman inequality.
description: 15 pages, to appear in Indag. Math. (N.S.)
Sonnenfleckenzeichnung Nr. 40.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.02.2010, 11:30, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 178.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.08.2010, 08:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 53.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.03.2010, 08:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Optimal Dosage and Administration Practices for Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate
Creators: name: Darsey, D.A.
name: Rhoney, D.H.
name: Chester, K.W.
Publisher: name: SAGE Publications Ltd
Year: 2020

description: Expert consensus and international guidelines recommend urgent co-administration of vitamin K and 4-factor prothrombin complex concentrates (4F-PCCs) to rapidly reverse VKA-related bleeding. This narrative review examined real-world evidence and strategies to optimize international normalized ratio (INR) reversal, hemostasis, and outcomes in patients receiving 4F-PCC in this setting. Key determinants for success include the appropriate use of alternative dosing and administration strategies, such as fixed dosing and increased infusion speed, adherence to institutional guidelines, and removing significant institutional barriers to reduce time to treatment. In the opinion of authors, minimizing the time to treatment with 4F-PCCs is of paramount importance when treating patients with VKA-related bleeding. Practices that safely and feasibly shorten the time to administration should be included in guidelines for institutions responsible for anticoagulant care, and adhered to in centers that perform invasive procedures on patients receiving VKA therapy. Further studies are required to optimize use of 4F-PCC, particularly in relation to the ideal dosing strategy and the role of INR.
ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness.
Creators: name: Werner, Marcel
name: Dyas, Anna
name: Parfentev, Iwan
name: Schmidt, Geske E
name: Mieczkowska, Iga K
name: Müller-Kirschbaum, Lukas C
name: Müller, Claudia
name: Kalkhof, Stefan
name: Reinhardt, Oliver
name: Urlaub, Henning
name: Alves, Frauke
name: Gallwas, Julia
name: Prokakis, Evangelos
name: Wegwitz, Florian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/67/1347
/631/67/71
/631/67/395
/631/67/1857
/13/100
/38/91
/42/89
/82/58
/96/106
/64/60
article

description: Basal-like breast cancer (BLBC) is a highly aggressive breast cancer subtype frequently associated with poor prognosis. Due to the scarcity of targeted treatment options, conventional cytotoxic chemotherapies frequently remain the standard of care. Unfortunately, their efficacy is limited as BLBC malignancies rapidly develop resistant phenotypes. Using transcriptomic and proteomic approaches in human and murine BLBC cells, we aimed to elucidate the molecular mechanisms underlying the acquisition of aggressive and chemotherapy-resistant phenotypes in these mammary tumors. Specifically, we identified and characterized a novel short isoform of Roundabout Guidance Receptor 3 (ROBO3s), upregulated in BLBC in response to chemotherapy and encoding for a protein variant lacking the transmembrane domain. We established an important role for the ROBO3s isoform, mediating cancer stem cell properties by stimulating the Hippo-YAP signaling pathway, and thus driving resistance of BLBC cells to cytotoxic drugs. By uncovering the conservation of ROBO3s expression across multiple cancer types, as well as its association with reduced BLBC-patient survival, we emphasize its potential as a prognostic marker and identify a novel attractive target for anti-cancer drug development.
Sonnenfleckenzeichnung Nr. 226.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.09.2010, 08:30, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 284.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.12.2010, 11:15, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502307) John George Green
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Is working from home a blessing or a burden? Home demands as a mediator of the relationship between work engagement and work-life balance
Creators: name: Ugwu, Fabian Onyekachi
name: Enwereuzor, Ibeawuchi K.
name: Mazei, Jens
Publisher: name: TU Dortmund
Year: 2022
Subjects: subject: Working from home
subject: Work engagement
subject: Home demands
subject: Work-life balance
subject: Nigeria
subject: 150
subject: Telearbeit
subject: Arbeitsqualität
subject: Work-Life-Balance
subject: Nigeria

description: As COVID-19 pandemic made its incursion into the world of work in early 2020, many employees were compelled to work from home to slow down the transmission of the disease. Since then, it has been asked whether working from home is a blessing or a burden. We respond to this question by building on the Affective Events Theory to examine whether work engagement is related to work-life balance (WLB), and whether home demands mediate this relationship, using data from 219 knowledge workers drawn from universities in the South-eastern region of Nigeria primarily working from home when they were surveyed. Results of regression analysis using PROCESS macro showed that work engagement related positively to home demands; in turn, home demands related negatively to WLB. The results further revealed that work engagement related negatively to WLB and that home demands mediated the negative work engagement-WLB connection. Theoretical as well as practical implications of the study are discussed, limitations are highlighted, and suggestions for future research are outlined.
description: Applied research in quality of life;18(1)