cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Oral-health status of children and adolescents with adverse childhood experiences : a pilot study with the Elizabeth Fry Society of Greater Vancouver
Creators: name: Bahri Iraei, Tila
Publisher: name: University of British Columbia
Year: 2017

description: Objectives: Adverse childhood experiences (ACE) such as poverty, parental substance use and parental incarceration can have negative influences on the physical and mental growth and development of children. The Elizabeth Fry (EFry) Society of Greater Vancouver, which provides a variety of services to children impacted by ACE in British Columbia, expressed interest in knowing about the oral health status of the clients they serve, so that appropriate support and services could be developed as needed. The objectives of this study were to document oral-health-related behaviours of children and youth who receive services from EFry, asses and describe their current oral-health status and explore relationships between a variety of study variables including demographics (age, gender, ethnicity), social characteristics (parent in justice system), and health behaviours and oral health status. Methods: Children and adolescents from a summer camp operated by EFry completed socio-demographic and oral- health -behaviour questionnaires. A clinical examination including an assessment of dental status (dmft/DMFT), oral hygiene status (DI-S) and gingival status (GI) was conducted on each participant. Analysis included descriptive statistics, as well as bivariate tests to determine relationships between dental health status and a variety of study variables. Results: The 67 participants of this study, aged 6 to 16 years of age, had a mean dmft /DMFT of 3.64 with 78% having at least one decayed, missed or filled tooth. About one-fifth (19%) of children and one-third of adolescents (35%) had received fissure sealants. Of the participants, 21% and 75% had mild or moderate gingival inflammation respectively. The majority of children and adolescents (69%) had minimal tooth debris and 28% had moderate debris. No statistically significant relationship was found between dmft/DMFT and any of the study variables, including oral health behaviours. Conclusion: For this limited small volunteer sample of EFry children and adolescents, no relationship was found between any participant characteristics and oral health status. The participants appear to be receiving needed definitive dental care however, preventive measures, specifically fissure sealants were lacking. A greater emphasis on preventive care for these children may help to ensure future oral health.
An evaluation of a junior high school remedial reading program
Creators: name: Johnson, Ethel Lois Rigby, 1925-
Publisher: name: The University of Texas at Austin
Year: 1961
Subjects: subject: Reading--Remedial teaching--Texas--Edinburgh
subject: Central Junior High School (Edinburgh, Tex.)

description: The subject of this thesis is the description and evaluation of my own reading classes. Writing it has taught me a great deal, and I sincerely hope that it will be of some value to others also. The remedial reading program in my school has been underway for about three years. As a teacher, I felt that some type of evaluation was necessary. This study was made to appraise the program as it is and to propose changes by the results indicated. Both objective and subjective data have been employed in the analysis. During the statistical analysis, I found out what most statisticians already know--that figures don't always come out the way we want them to. However, the statistical analysis in the study is limited by the relatively few students involved. The subjective evaluation is more encouraging.
Homotheties and topology of tangent sphere bundles
Creators: name: Albuquerque, Rui
Publisher: name: arXiv
Year: 2010
Subjects: subject: Differential Geometry (math.DG)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: Primary: 55R25, Secondary: 53A30, 53C07, 53C17, 57R20

description: We prove a Theorem on homotheties between two given tangent sphere bundles $S_rM$ of a Riemannian manifold $M,g$ of $\dim\geq 3$, assuming different variable radius functions $r$ and weighted Sasaki metrics induced by the conformal class of $g$. New examples are shown of manifolds with constant positive or with constant negative scalar curvature, which are not Einstein. Recalling results on the associated almost complex structure $I^G$ and symplectic structure $ω^G$ on the manifold $TM$, generalizing the well-known structure of Sasaki by admitting weights and connections with torsion, we compute the Chern and the Stiefel-Whitney characteristic classes of the manifolds $TM$ and $S_rM$.
description: 15 pages, to appear in Journal of Geometry
Brillouin amplification in compound (AIIIBV and AIIBVI) semiconductors: effects of piezoelectricity, doping and external magnetostatic field
Creators: name: Singh, Manjeet
Publisher: name: Rangsit University
Year: 2022
Subjects: AIIIBV and AIIBVI semiconductors
Brillouin cell efficiency
Laser-semiconductor interactions
stimulated Brillouin amplification

description: Journal of Current Science and Technology, 12, 1, 61-78
Central Areolar Choroidal Dystrophy (CACD) and Age-related macular degeneration (AMD): differentiating characteristics in multimodal imaging
Creators: name: Smailhodzic, D.
name: Fleckenstein, M.
name: Theelen, T.
name: Boon, C. J.
name: van Huet, R. A.
name: van de Ven, J. P.
name: Den Hollander, A. I.
name: Schmitz-Valckenberg, S.
name: Hoyng, C. B.
name: Weber, Bernhard H. F.
name: Holz, F. G.
name: Klevering, B. J.
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: 610 Medizin

description: Purpose.: Late-onset central areolar choroidal dystrophy (CACD) may easily be confused with geographic atrophy (GA) in AMD. To detect discerning features, the morphologic changes in CACD patients and in AMD patients were assessed with confocal scanning laser ophthalmoscopy (cSLO), fundus autofluorescence (FAF), and spectral-domain optical coherence tomography (SD-OCT). Methods.: A total of 30 CACD patients with identified PRPH2 gene mutations were analyzed and compared to 19 patients with early AMD and 13 patients with AMD-associated GA. The presence of drusen and pigment clumping was determined with color fundus photography. High-resolution in vivo imaging was performed with cSLO and SD-OCT. FAF images and SD-OCT volume scans were analyzed in each study eye. Results.: On FAF, a speckled FAF pattern occurred significantly more often in CACD (85%) than in early AMD (5.6%; P < 0.0001). There was a significantly higher frequency of sub-RPE deposits in eyes with AMD than in eyes with CACD (36.8% versus 2.1% of scans, P = 0.0019). Reticular drusen could be visualized by SD-OCT and FAF imaging in 52.6% of the eyes with early AMD and in 100% of the eyes with GA, whereas this drusen phenotype did not manifest in eyes with CACD. Conclusions.: Although outer retinal atrophy is the clinically common feature in advanced CACD as well as GA, there are microstructural alterations on high-resolution SD-OCT and FAF imaging that allow for the differentiation between CACD and AMD. The findings may help to identify patients in whom a diagnostic PRPH2 screening is warranted. (ClinicalTrials.gov number, NCT00393692.)
Benchmarking SciCat Performance: Data-In & Data-Out for Beamline Operations .
Creators: name: Khokhriakov, Igor
Publisher: name: Zenodo
Year: 2025

description: This work was partially supported by the consortium DAPHNE4NFDI in thecontext of the work of the NFDI e.V. The consortium is funded bythe Deutsche Forschungsgemeinschaft (DFG, German ResearchFoundation) - project number 460248799.
Prostate-specific antigen (PSA) glycan-binding profile analysis based on enzyme-linked lectin assay (ELLA) and storage effect of assay components
Creators: name: Shahidan, Muhammad Ashraf
Publisher: name: Rangsit University
Year: 2022
Subjects: glycoprofiling
lectin assay
MAA
PSA
sialic acid
SNA
storage

description: Journal of Current Science and Technology, 12, 1, 79-88
Dynamics of quantum quenching for BCS-BEC systems in the shallow BEC regime
Creators: name: Roy, Analabha
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: The problem of coupled Fermi-Bose mixtures of an ultracold gas near a narrow Feshbach resonance is approached through the time-dependent and complex Ginzburg-Landau (TDGL) theory. The dynamical system is constructed using Ginzburg-Landau-Abrikosov-Gor'kov (GLAG) path integral methods with the single mode approximation for the composite Bosons, and the equilibrium states are obtained in the BEC regime for adiabatic variations of the Feshbach detuning along the stationary solutions of the dynamical system. Investigations into the rich superfluid dynamics of this system in the shallow BEC regime yields the onset of multiple interference patterns in the dynamics as the system is quenched from the deep-BEC regime. This results in a partial collapse and revival of the coherent matter wave field of the BEC, whose temporal profile is reported.
description: 24 pages, 7 figures. Submitted to European Journal of Physics Plus
The spatial Λ-Fleming-Viot process on a large torus: Genealogies in the presence of recombination
Creators: name: Etheridge, A. M.
name: Véber, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: We extend the spatial $Λ$-Fleming-Viot process introduced in [Electron. J. Probab. 15 (2010) 162-216] to incorporate recombination. The process models allele frequencies in a population which is distributed over the two-dimensional torus $\mathbb{T}(L)$ of sidelength L and is subject to two kinds of reproduction events: small events of radius $\mathcal{O}(1)$ and much rarer large events of radius $\mathcal{O}(L^α)$ for some $α\in(0,1]$. We investigate the correlation between the times to the most recent common ancestor of alleles at two linked loci for a sample of size two from the population. These individuals are initially sampled from "far apart" on the torus. As L tends to infinity, depending on the frequency of the large events, the recombination rate and the initial distance between the two individuals sampled, we obtain either a complete decorrelation of the coalescence times at the two loci, or a sharp transition between a first period of complete correlation and a subsequent period during which the remaining times needed to reach the most recent common ancestor at each locus are independent. We use our computations to derive approximate probabilities of identity by descent as a function of the separation at which the two individuals are sampled.
description: Published in at http://dx.doi.org/10.1214/12-AAP842 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Systemic complement activation in age-related macular degeneration
Creators: name: Scholl, H. P.
name: Charbel Issa, P.
name: Walier, M.
name: Janzer, S.
name: Pollok-Kopp, B.
name: Börncke, F.
name: Fritsche, L. G.
name: Chong, N. V.
name: Fimmers, R.
name: Wienker, T.
name: Holz, F. G.
name: Weber, Bernhard H. F.
name: Oppermann, M.
Publisher: name: Universität Regensburg
Year: 2008
Subjects: subject: 610 Medizin

description: Dysregulation of the alternative pathway (AP) of complement cascade has been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of blindness in the elderly. To further test the hypothesis that defective control of complement activation underlies AMD, parameters of complement activation in blood plasma were determined together with disease-associated genetic markers in AMD patients. Plasma concentrations of activation products C3d, Ba, C3a, C5a, SC5b-9, substrate proteins C3, C4, factor B and regulators factor H and factor D were quantified in patients (n = 112) and controls (n = 67). Subjects were analyzed for single nucleotide polymorphisms in factor H (CFH), factor B-C2 (BF-C2) and complement C3 (C3) genes which were previously found to be associated with AMD. All activation products, especially markers of chronic complement activation Ba and C3d (p<0.001), were significantly elevated in AMD patients compared to controls. Similar alterations were observed in factor D, but not in C3, C4 or factor H. Logistic regression analysis revealed better discriminative accuracy of a model that is based only on complement activation markers Ba, C3d and factor D compared to a model based on genetic markers of the complement system within our study population. In both the controls' and AMD patients' group, the protein markers of complement activation were correlated with CFH haplotypes. This study is the first to show systemic complement activation in AMD patients. This suggests that AMD is a systemic disease with local disease manifestation at the ageing macula. Furthermore, the data provide evidence for an association of systemic activation of the alternative complement pathway with genetic variants of CFH that were previously linked to AMD susceptibility.
Interlaminar shear strength of chemically treated Kevlar/Cucurbitaceae fiber metal laminated hybrid composites
Creators: name: Ramasamy Nallamuthu
Publisher: name: Rangsit University
Year: 2022
Subjects: chemical treatment
fiber metal laminates
interphase
sequencing layer
surface modification

description: Journal of Current Science and Technology, 12, 1, 102-109
Cellular localization of the MPP4 protein in the mammalian retina
Creators: name: Stöhr, H.
name: Stojic, J.
name: Weber, Bernhard H. F.
Publisher: name: Universität Regensburg
Year: 2003
Subjects: subject: 610 Medizin

description: purpose. Membrane protein, palmitoylated (MPP)-4 is a novel retina-specific member of the p55-like subfamily of membrane-associated guanylate kinases (MAGUKs). MAGUKs are known to act as scaffolding molecules for multiprotein complexes at specialized regions of the plasma membrane. The goal of this study was to characterize the MPP4 protein and to determine its location in the mammalian retina. methods. RT-PCR and 5′ and 3′ rapid amplification of cDNA ends (RACE) techniques were used to isolate and sequence the full-length bovine MPP4 cDNA. Polyclonal antisera against the bovine MPP4 protein were generated in rabbits immunized with synthetic peptides. Affinity-purified anti-MPP4 antibodies were used to investigate the properties and distribution of MPP4 in retina and transfected 293-Ebna cells by Western blot analysis and immunofluorescence microscopy. results. The full-length bovine MPP4 cDNA encodes a putative bovine MPP4 protein of 640 amino acids with a predicted molecular mass of 72.9 kDa. Affinity-purified anti-MPP4 antibodies specifically detected the MPP4 protein in extracts from retina and 293-Ebna cells transfected with the MPP4 cDNA. Immunofluorescence analyses revealed that both the bovine and porcine MPP4 proteins are localized in the connecting cilia and synaptic terminals of cone and rod photoreceptors. In addition, postsynaptic structures in the outer plexiform layer and three distinct bands in the inner plexiform layer were MPP4-positive. In porcine but not bovine retina, a subclass of cone bipolar cells were labeled with anti-MPP4. conclusions. The concurrent presence of MPP4 in connecting cilia and synaptic structures suggests that MPP4 plays a role at membrane–cytoskeleton interfaces in distinct structural and functional compartments of bovine and porcine retinas. This work provides the basis for further investigations into the function of MPP4 as a retinal scaffolding molecule and its possible role in retinal disease.
Fast integral equation methods for the modified Helmholtz equation
Creators: name: Kropinski, Mary-Catherine
name: Quaife, Bryan
Publisher: name: arXiv
Year: 2010
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We present a collection of integral equation methods for the solution to the two-dimensional, modified Helmholtz equation, $u(\x) - α^2 Δu(\x) = 0$, in bounded or unbounded multiply-connected domains. We consider both Dirichlet and Neumann problems. We derive well-conditioned Fredholm integral equations of the second kind, which are discretized using high-order, hybrid Gauss-trapezoid rules. Our fast multipole-based iterative solution procedure requires only O(N) or $O(N\log N)$ operations, where N is the number of nodes in the discretization of the boundary. We demonstrate the performance of the methods on several numerical examples.
description: Published in Computers & Mathematics with Applications
Genome-wide expression profiling of the retinoschisin-deficient retina in early postnatal mouse development
Creators: name: Gehrig, A.
name: Langmann, T.
name: Horling, F.
name: Janssen, A.
name: Bonin, M.
name: Walter, M.
name: Poths, S.
name: Weber, Bernhard H. F.
Publisher: name: Universität Regensburg
Year: 2007
Subjects: subject: 610 Medizin

description: purpose. The Rs1h knockout mouse displays retinal features typical for X-linked juvenile retinoschisis (RS). Consequently, this mouse line represents an excellent model to study early molecular events in RS. methods. Whole genome expression profiling using DNA-microarrays was performed on total RNA extracts from retinoschisin-deficient and wild-type murine retinas from postnatal days 7, 9, 11, and 14. Quantitative real-time RT-PCR (qRT-PCR) analysis of additional time points facilitated the refinement of the temporal expression profile of differentially regulated transcripts. Differential protein expression was confirmed by Western blot analysis. results. Based on biostatistic and knowledge-based DNA-microarray analyses we have identified differentially regulated retinal genes in early postnatal stages of the Rs1h-deficient mouse defining key molecular pathways including adhesion, cytoskeleton, vesicular trafficking, and immune response. A significant upregulation of Egr1 at P11 and several microglia/glia-related transcripts starting at P11 with a peak at P14 were identified in the diseased retina. The results provided evidence that macrophage/microglia activation precedes apoptotic photoreceptor cell death. Finally, the role of Egr1 in the pathogenesis of Rs1h-deficiency was investigated, and the results indicated that activation of the MAPK Erk1/2 pathway occurs as early as P7. Analyses of Rs1h −/Y /Egr1 −/− double-knockout mice suggest that Egr1 upregulation is not a prerequisite for macrophage/microglia activation or apoptosis. conclusions. The findings imply that microglia/glia activation may be triggering events in the photoreceptor degeneration of retinoschisin-deficient mice. Furthermore, the data point to a role of Erk1/2-Egr1 pathway activation in RS pathogenesis.
Fano stability diagram of a symmetric triple quantum dot
Creators: name: Niklas, Michael
name: Trottmann, Andreas
name: Donarini, Andrea
name: Grifoni, Milena
Publisher: name: Universität Regensburg
Year: 2017
Subjects: subject: 530 Physik
subject: 73.23.Hk
subject: 73.63.Kv

description: The Fano factor stability diagram of a C3v symmetric triangular quantum dot is analysed for increasing electron fillings N. At low filling, conventional Poissonian and sub-Poissonian behavior, caused by the interplay of electron-electron interactions and Fermi statistics, is found. At larger filling, N ≥ 2, super-Poissonian noise and a peculiar bias voltage dependence of the Fano factor are observed at Coulomb and interference blockade. An analysis of the Fano map unravels a nontrivial electron bunching mechanism arising from the presence of degenerate many-body states combined with orbital interference and Coulomb interactions.
Supernovae from Red Supergiants with Extensive Mass Loss
Creators: name: Moriya, Takashi
name: Tominaga, Nozomu
name: Blinnikov, Sergei I.
name: Baklanov, Petr V.
name: Sorokina, Elena I.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We calculate multicolor light curves (LCs) of supernovae (SNe) from red supergiants (RSGs) exploded within dense circumstellar medium (CSM). Multicolor LCs are calculated by using a multi-group radiation hydrodynamics code STELLA. If CSM is dense enough, the shock breakout signal is delayed and smeared by CSM and kinetic energy of SN ejecta is efficiently converted to thermal energy which is eventually released as radiation. We find that explosions of RSGs are affected by CSM in early epochs when mass-loss rate just before the explosions is higher than 10^{-4} Msun/yr. Their characteristic features are that the LC has a luminous round peak followed by a flat LC, that multicolor LCs are simultaneously bright in ultraviolet and optical at the peak, and that photospheric velocity is very low at these epochs. We calculate LCs for various CSM conditions and explosion properties, i.e., mass-loss rates, radii of CSM, density slopes of CSM, explosion energies of SN ejecta, and SN progenitors inside, to see their influence on LCs. We compare our model LCs to those of ultraviolet-bright Type IIP SN 2009kf and show that the mass-loss rate of the progenitor of SN 2009kf just before the explosion is likely to be higher than 10^{-4} Msun/yr. Combined with the fact that SN 2009kf is likely to be an energetic explosion and has large 56Ni production, which implies that the progenitor of SN 2009kf is a massive RSG, our results indicate that there could be some mechanism to induce extensive mass loss in massive RSGs just before their explosions.
description: 16 pages, 17 figures, 3 tables, accepted by Monthly Notices of the Royal Astronomical Society, the unit of Lbol in Table 3 corrected in v3
Charcoal and gravel basin lined solar still for brackish water purification
Creators: name: Nsikan Ime Obot
Publisher: name: Rangsit University
Year: 2022
Subjects: basin lining
brackish water treatment
energy storage materials
equatorial site
floating charcoal, solar distiller
submerged black gravel

description: Journal of Current Science and Technology, 12, 1, 110-127
Profiling of WDR36 missense variants in German patients with glaucoma
Creators: name: Pasutto, F.
name: Mardin, C. Y.
name: Michels-Rautenstrauss, K.
name: Weber, Bernhard H. F.
name: Sticht, H.
name: Chavarria-Soley, G.
name: Rautenstrauss, B.
name: Kruse, F.
name: Reis, A.
Publisher: name: Universität Regensburg
Year: 2008
Subjects: subject: 610 Medizin

description: purpose. Mutations in WDR36 were recently reported in patients with adult-onset primary open-angle glaucoma (POAG). In this study, the prevalence of WDR36 variants was investigated in patients with glaucoma who were of German descent with diverse age of onset and intraocular pressure levels. methods. Recruited were 399 unrelated patients with glaucoma and 376 healthy subjects of comparable age and origin, who had had repeated normal findings in ophthalmic examinations. The frequency of observed variants was obtained by direct sequencing of the entire WDR36 coding region. results. A total of 44 WDR36 allelic variants were detected, including 14 nonsynonymous amino acid alterations, of which 7 are novel (P31T, Y97C, D126N, T403A, H411Y, H411L, and P487R) and 7 have been reported (L25P, D33E, A163V, H212P, A449T, D658G and I264V). Of these 14 variants, 6 were classified as polymorphisms as they were detected in patients and control individuals at similar frequencies. Eight variants present in 15 patients (3.7%) but only 1 control individual (0.2%) were defined as putative disease-causing variants (P = 0.0005). Within this patient group, 12 (80%) presented with high and 3 (20%) with low intraocular pressure. Disease severity and age of onset showed a broad range. conclusions. The occurrence of several rare putative disease-causing variants in patients with glaucoma suggests that WDR36 may be a minor disease-causing gene in glaucoma, at least in the German population. The large variability in WDR36, though, requires functional validation of these variants, once its function is characterized.
Growth inhibition of Escherichia coli and Pseudomonas aeruginosa strains by Piper betle Linn. extracts
Creators: name: Watcharacha Krongkeha
Publisher: name: Rangsit University
Year: 2022
Subjects: antibacterial activity
Escherichia coli
natural agent
Piper betle L.
Pseudomonas aeruginosa

description: Journal of Current Science and Technology, 12, 1, 141-150
Unusual blood clots with low blood platelets from Covid-19 viral vector vaccines
Creators: name: Pantapat Chokpitakkul
Publisher: name: Rangsit University
Year: 2022
Subjects: adenoviral vectors
ChAdOx nCov-19
PF4
vaccine-induced immune thrombotic thrombocytopenia

description: Journal of Current Science and Technology, 12, 1, 151-161
Heterozygous loss-of-function variants in CYP1B1 predispose to primary open-angle glaucoma
Creators: name: Pasutto, F.
name: Chavarria-Soley, G.
name: Mardin, C. Y.
name: Michels-Rautenstrauss, K.
name: Ingelman-Sundberg, M.
name: Fernández-Martínez, L.
name: Weber, Bernhard H. F.
name: Rautenstrauss, B.
name: Reis, A.
Publisher: name: Universität Regensburg
Year: 2010
Subjects: subject: 610 Medizin

description: Purpose.: Although primary congenital glaucoma (PCG)–associated CYP1B1 mutations in the heterozygous state have been evaluated for association with primary open-angle glaucoma (POAG) in several small studies, their contribution to the occurrence of POAG is still controversial. The present study was conducted to determine whether heterozygous functionally characterized CYP1B1 mutations are associated with the disease in a large cohort of German patients with POAG. Methods.: The frequency of CYP1B1 variants on direct sequencing of the entire coding region was compared in 399 unrelated German patients with POAG (270, POAG; 47, JOAG; and 82, NTG) and 376 control subjects without any signs of glaucoma on ophthalmic examination. In vitro functional assays were performed and relative enzymatic activity of the CYP1B1 variants embedded in their respective background haplotypes and not previously unambiguously classified were determined, to assess their possible causative role. Results.: Apart from known polymorphic variants, 11 amino acid substitutions in CYP1B1 reported before, both in PCG and POAG cases, were identified. After in vitro functional assay, variants P52L and R368H showed marked reduction of activity, confirming their role as loss-of-function mutations similar to previously determined variants G61E, N203S, and G329V. In contrast, variants G168D, A443G, and A465V showed no relevant effects and were thus classified as polymorphisms. Overall, seven functionally impaired variants were present in 13 (3.6%) patients and in 1 (0.2%) control subject (P = 0.002, OR = 5.4). Reanalysis of previous studies reporting CYP1B1 mutations in patients with POAG based on updated functional validation showed a significant excess of carriers among patients compared to controls (OR = 3.85; P = 2.3 × 10−7). Conclusions.: Heterozygous CYP1B1 mutations with absent or reduced relative enzymatic activity can be considered a risk factor for POAG.
MHV diagrams in twistor space and the twistor action
Creators: name: Adamo, Tim
name: Mason, Lionel
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: MHV diagrams give an efficient Feynman diagram-like formalism for calculating gauge theory scattering amplitudes on momentum space. Although they arise as the Feynman diagrams from an action on twistor space in an axial gauge, the main ingredients were previously expressed only in momentum space and momentum twistor space. Here we show how the formalism can be elegantly derived and expressed entirely in twistor space. This brings out the underlying superconformal invariance of the framework (up to the choice of a reference twistor used to define the axial gauge) and makes the twistor support transparent. Our treatment is largely independent of signature, although we focus on Lorentz signature. Starting from the N=4 super-Yang-Mills twistor action, we obtain the propagator for the anti-holomorphic Dolbeault-operator as a delta function imposing collinear support with the reference twistor defining the axial gauge. The MHV vertices are also expressed in terms of similar delta functions. We obtain concrete formulae for tree-level N^{k}MHV diagrams as a product of MHV amplitudes with an R-invariant for each propagator; here the R-invariant manifests superconformal as opposed to dual-superconformal invariance. This gives the expected explicit support on k+1 lines linked by k further lines associated to the propagators. The R-invariants arising correspond to those obtained in the dual conformal invariant momentum twistor version of the formalism, but differences arise in the specification of the boundary terms. Surprisingly, in this framework, some finite loop integrals can be performed as simply as those for tree diagrams.
description: 53 pages, 13 figures. v2: typos and error in discussion of loop diagrams corrected; v3: includes new derivation of momentum space MHV rules, 3 new appendices, and errors in statements concerning the cohomological interpretation are now corrected; v4: published version
Association of LOXL1 common sequence variants in German and Italian patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
Creators: name: Pasutto, F.
name: Krumbiegel, M.
name: Mardin, C. Y.
name: Paoli, D.
name: Lämmer, R.
name: Weber, Bernhard H. F.
name: Kruse, F. E.
name: Schlötzer-Schrehardt, U.
name: Reis, A.
Publisher: name: Universität Regensburg
Year: 2008
Subjects: subject: 610 Medizin

description: purpose. Three common sequence variants in the lysyl oxidase-like 1 (LOXL1) gene were recently associated with both pseudoexfoliation (PEX) and pseudoexfoliation glaucoma (PEXG) in populations from Iceland and Sweden. In this study, the genetic association of these variants was investigated in patients with PEX or PEXG of German and Italian descent. methods. The three LOXL1 single-nucleotide polymorphisms (SNPs), one intronic (rs2165241) and two nonsynonymous coding SNPs (rs1048661: R141L and rs3825942: G153D) were genotyped in a total of 726 unrelated patients with PEX or PEXG (517 Germans and 209 Italians) and 418 healthy subjects who had normal findings in repeated ophthalmic examinations, and a genetic association study was performed. results. Strong association with the three LOXL1 common sequence variants was seen in both the PEX and PEXG patient groups independent of their geographic origin (rs2165241, combined OR = 3.42, P = 1.28 × 10−40; rs1048661, OR = 2.43, P = 2.90 × 10−19; and rs3825942, OR = 4.87, P = 8.22 × 10−23). Similarly, the common frequent haplotype (G-G) composed of the two coding SNPs (rs1048661 and rs3825942) was strongly associated in PEX and PEXG cohorts of both populations with the disease (combined OR = 3.58, P = 5.21× 10−43). conclusions. Genetic variants in LOXL1 confer risk to PEX in German and Italian populations, independent of the presence of secondary glaucoma, confirming findings in patients from Northern Europe.
Novel biomarkers and protein-protein interaction in multiple myeloma
Creators: name: Naamani, Linda
name: Silverman, Rosalind
name: Silverman, Lorelei
Publisher: name: figshare
Year: 2022
Subjects: subject: 110703 Autoimmunity
subject: FOS: Clinical medicine
subject: Biomarkers
subject: 111201 Cancer Cell Biology
subject: 111202 Cancer Diagnosis
subject: 111203 Cancer Genetics
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
subject: 110704 Cellular Immunology
subject: 111205 Chemotherapy
subject: Diseases
subject: 110202 Haematology
subject: 110707 Innate Immunity
subject: 110799 Immunology not elsewhere classified
subject: 110706 Immunogenetics (incl. Genetic Immunology)
subject: 110705 Humoural Immunology and Immunochemistry
subject: 110106 Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)
subject: 110311 Medical Genetics (excl. Cancer Genetics)
subject: FOS: Basic medicine
subject: 111207 Molecular Targets
subject: 111208 Radiation Therapy

description: The Biomarkers of disease’ project was designed to use proteomics and bioinformatics, in order to discover novel biomarkers associated with different diseases, that can be used as a diagnostic tool or to aid in target drug therapy. In this paper, we focus on multiple myeloma (MM), which is the second most common hematological malignancy with an incidence of 55 per 1 000 000 people in Canada . Multiple myeloma is a malignancy of plasma cells, which are differentiated B lymphocytes, and they function to produce antibodies in response to pathogens That said, plasma cells also play a role in the development of allergies and autoimmune diseases. Plasma cells that are short lived are easily depleted by drugs that slows or stops the growth of cells, however, long-lived plasma cells may give rise to autoantibodies that are relatively resistant to therapy. Multiple myeloma arises when plasma cells are poorly regulated. The cause of multiple myeloma is poorly understood, but a study in Canada has shown that the occurrence of MM is more common in rural areas and agricultural cities (5). This gives rise to the identification of pesticides and chemicals used for farming as risk factors in the pathogenesis of MM. Well known risk factors for MM are advancing age, black race, and male sex (6), as well as other factors including obesity, ionising radiation, and infections with HIV and Hepatitis C. The typical symptoms of MM can be summarized into the acronym ‘CRAB’, which stands for hypercalcemia, renal failure, anemia, and bone disease . Although not all patients exhibit the usual CRAB symptoms; a study demonstrated that only 74% of MM patients displayed the typical symptoms of CRAB while 20% had different symptoms.
Use and perceptions of the Emergency Slaughter Program in British Columbia
Creators: name: Koralesky, Katherine Elizabeth
Publisher: name: University of British Columbia
Year: 2017

description: When dealing with acutely injured or non-ambulatory dairy cows, dairy producers in British Columbia must decide whether to treat, ship, euthanize, or use the Emergency Slaughter Program (ESP). This thesis focused on the last of these options. The specific injuries and conditions that result in ESP use are unknown, although identification of these reasons could allow additional monitoring of cows when they may be vulnerable to emergency slaughter, and determine the most appropriate reasons for ESP use. Analysis of 812 ante-mortem inspection documents found that a large proportion of cows in the ESP were non-ambulatory (63%) or had sustained what were likely calving-related injuries (37%). Two distinct uses for the ESP emerged including 1) traumatic incidents (i.e. emergencies) such as a fractured femur and 2) ‘inhumane to transport’, a category that likely includes non-emergencies such as lameness where cows were not necessarily in acute distress but could not be transported humanely. Anecdotal reports suggest that the ESP may be controversial among dairy industry professionals, but to date the overall perceptions including concerns and benefits of the program are unknown. Understanding these perceptions can be used to provide recommendations for improving the ESP particularly in situations where cow welfare is compromised and individuals must make decisions in potentially uncertain and unwanted situations. Interviews and focus groups with 40 dairy industry professionals revealed positive and negative perceptions of the ESP influenced by 1) an individual’s values, 2) the perceived operational legitimacy of the ESP and 3) overarching concerns about the dairy industry. Resulting recommendations for the ESP include: 1) clarification of cow conditions that warrant the use of the ESP for non-emergency situations, 2) additional training for veterinarians on ante-mortem inspection, 3) specification of precise timing parameters for when the ESP can be used, 4) the use of proper equipment and procedures that ensure meat quality and hygiene of carcasses, 5) added collaboration between slaughterhouses, transporters, veterinarians, producers and the dairy industry to allow the appropriate use of the ESP in other parts of British Columbia and 6) proactive culling and the use of on-farm protocols for making end-of-life decisions.
Exploring functional candidate genes for genetic association in German patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
Creators: name: Krumbiegel, M.
name: Pasutto, F.
name: Mardin, C. Y.
name: Weisschuh, N.
name: Paoli, D.
name: Gramer, E.
name: Zenkel, M.
name: Weber, Bernhard H. F.
name: Kruse, F. E.
name: Schlötzer-Schrehardt, U.
name: Reis, A.
Publisher: name: Universität Regensburg
Year: 2009
Subjects: subject: 610 Medizin

description: purpose. Pseudoexfoliation (PEX) syndrome is a generalized elastic microfibrillopathy characterized by fibrillar deposits in intra- and extraocular tissues. Genetic and nongenetic factors are known to be involved in its etiopathogenesis. This study was focused on six functional candidate genes involved in PEX material deposition and the analysis of their potential association with PEX syndrome and PEX glaucoma (PEXG). methods. Fifty single-nucleotide polymorphisms (SNPs) capturing >95% of overall genetic variance observed in Europeans at loci for FBN1, LTBP2, MFAP2, TGM2, TGF-b1, and CLU were genotyped in 333 unrelated PEX-affected and 342 healthy individuals of German origin, and a genetic association study was performed. To replicate the findings, two SNPs of the CLU gene were genotyped in a further 328 unrelated German patients with PEX as well as in 209 Italian patients with PEX and 190 Italian control subjects. results. Association with PEX was observed only for the SNP rs2279590 in intron 8 of the CLU gene coding for clusterin (corrected P = 0.0347, OR = 1.34) in our first German cohort. Likewise, a frequent haplotype encompassing the associated risk allele showed nominally significant association. None of remaining SNPs or SNP haplotypes were associated with PEX. The association found was confirmed in a second German cohort (P = 0.0244) but not in the Italian cohort (P = 0.7173). In addition, the association with CLU SNP rs2279590 was more significant in German patients with PEX syndrome than in those with PEXG. conclusions. Genetic variants in the gene encoding clusterin may represent a risk factor for PEX in German patients but not in Italian patients. Variants in FBN1, LTBP2, MFAP2, TGF-b1, and TGM2 do not play a major role in the etiology of PEX syndrome, at least in German patients.
Experiences with American ginseng in Finland - Amerikanginsengin koeviljely
Creators: name: Galambosi
name: , Bertalan
Publisher: name: Zenodo
Year: 2019
Subjects: ginseng
innovations
alternative crops
Finland
Amerikangingsen
koeviljely
gingsengjuuri
gingsengtuotteet
Panax quinquefolium
viljelykokeilut Suomessa

description: The presentation shows existing ginseng products in Finland, and experiences with ginseng plantations in Finland. Further information references are also included.
Seasonal and regional characterization of horizontal stirring in the global ocean
Creators: name: Hernández-Carrasco, I.
name: López, C.
name: Hernández-García, E.
name: Turiel, A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Recent work on Lagrangian descriptors has shown that Lyapunov Exponents can be applied to observed or simulated data to characterize the horizontal stirring and transport properties of the oceanic flow. However, a more detailed analysis of regional dependence and seasonal variability was still lacking. In this paper, we analyze the near-surface velocity field obtained from the Ocean general circulation model For the Earth Simulator (OFES) using Finite-Size Lyapunov Exponents (FSLE). We have characterized regional and seasonal variability. Our results show that horizontal stirring, as measured by FSLEs, is seasonally-varying, with maximum values in Summer time. FSLEs also strongly vary depending on the region: we have first characterized the stirring properties of Northern and Southern Hemispheres, then the main oceanic basins and currents. We have finally studied the relation between averages of FSLE and some Eulerian descriptors such as Eddy Kinetic Energy (EKE) and vorticity (w) over the different regions.
description: 32 pages, 7 figures
Particle motion in weak relativistic gravitational fields
Creators: name: Obradovic, Miki
name: Kunz, Martin
name: Hindmarsh, Mark
name: Iliev, Ilian T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We derive the geodesic equation of motion in the presence of weak gravitational fields produced by relativistic sources such as cosmic strings, decomposed into scalar, vector and tensor parts. We find that the vector (gravito-magnetic) force is an important contributor, and for non-relativistic particles we recover the well-known result for the impulse from a moving straight string. Our results can be straightforwardly incorporated into N-body simulations to allow for the presence of cosmic defects or other sources of weak gravitational fields.
description: 9 pages, 5 figures
Sustainable synthesis of organic framework-derived ZnO nanoparticles for fabrication of supercapacitor electrode
Creators: name: Shaheen, Irum
name: Ahmad, Khuram Shahzad
name: Zequine, Camila
name: Gupta, Ram K.
name: Thomas, Andrew G.
name: Malik, Mohammad Azad
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Plasma Physics

description: The phytosynthesis of metal oxides nanoparticles (NPs) has been extensively reported; yet mechanism involved and incorporated bioactive compounds in the synthesized NPs are still need to be investigated. In this regard, here an efficient sustainable co-precipitation synthesis of zinc oxide nanoparticles (ZnO NPs) has been developed, employing hydrothermal reactions, using organic compounds of Nasturtium officinale leaves. Pure hexagonal wurtzite ZnO was identified by X-ray diffraction and NPs in the size range of 50–60 nm were observed by field emission scanning electron microscopy. X-ray photoelectron spectroscopy revealed surface modification of ZnO by functional groups associated with the incorporated bio active compounds of Nasturtium officinale. The phyto-functionalized ZnO NPs having anoptical direct band gap of 3.29 eV and optical band gap energy of 2.85 eV were evaluated by cyclic voltammetry at various scan rates, galvanostatic charge–discharge at a range of current densities and electrochemical impedance spectroscopy (Z′ vs. Z″ and Z vs. frequency) in aqueous electrolyte. The fabricated ZnO-based electrode revealed a specific capacitance of 86.5 F/g at 2 mV/s with 97% coulombic efficiency for 2000 cycles. The good electrochemical conductivity was demonstrated by lower internal resistance of 1.04 Ω. Therefore, the present study suggested the significant potential of organic compounds incorporated ZnO NPs towards supercapacitor.
Revival of quantum correlations without system-environment back-action
Creators: name: Franco, Rosario Lo
name: Bellomo, Bruno
name: Andersson, Erika
name: Compagno, Giuseppe
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Revivals of quantum correlations have often been explained in terms of back-action on quantum systems by their quantum environment(s). Here we consider a system of two independently evolving qubits, each locally interacting with a classical random external field. The environments of the qubits are also independent, and there is no back-action on the qubits. Nevertheless, entanglement, quantum discord and classical correlations between the two qubits may revive in this model. We explain the revivals in terms of correlations in a classical-quantum state of the environments and the qubits. Although classical states cannot store entanglement on their own, they can play a role in storing and reviving entanglement. It is important to know how the absence of back-action, or modelling an environment as classical, affects the kind of system time evolutions one is able to describe. We find a class of global time evolutions where back-action is absent and for which there is no loss of generality in modelling the environment as classical. Finally, we show that the revivals can be connected with the increase of a parameter used to quantify non-Markovianity of the single-qubit dynamics.
description: 8 pages, 4 figures; this version to appear in Phys. Rev. A
Total Hip Arthroplasty through the Mini-Incision (Micro-Hip) Approach versus the Standard Transgluteal (Bauer) Approach: A Prospective, Randomised Study
Creators: name: Dienstknecht, T.
name: Lüring, C.
name: Tingart, Markus
name: Grifka, Joachim
name: Sendtner, Ernst
Publisher: name: Universität Regensburg
Year: 2014
Subjects: subject: arthroplasty, replacement, hip; pain, postoperative
subject: 610 Medizin

description: Purpose To compare outcome after total hip arthroplasty (THA) through the mini-incision approach versus the standard transgluteal approach. Methods 80 women and 63 men aged 33 to 89 (mean, 62) years with primary osteoarthritis of the hip were randomised to undergo unilateral THA through a mini-incision approach (Micro-hip, n=55) or standard, lateral, transgluteal approach (Bauer, n=88). Levels of haemoglobin, haematocrit, serum creatine kinase, and C-reactive protein, length of hospital stay, mobilisation, and any complication were recorded. Visual analogue scale (VAS) for pain was assessed. Hip function was assessed using the Harris Hip Score and the Oxford Hip Score, whereas general health was assessed using the EQ-5D general health questionnaire. The cup inclination and varus/ valgus of the stem position were measured using a goniometer. Results The Micro-hip group achieved a significantly lower mean incision length (9.3 vs. 13.4 cm, p<0.001), mean surgical time (60 vs. 68 minutes, p=0.021), mean reduction in haemoglobin level (2.1 vs. 2.8 g/dl, p<0.001), and mean VAS for pain from hour 6 to day 6 (all p<0.05). One patient in the Micro-hip group developed early aseptic loosening of the cup and underwent revision surgery at month 4. Three patients in the Bauer group and one patient in the Micro-hip group sustained intra-operative non-displaced fractures of the proximal femur, which were fixed with cerclages. Two patients in the Micro-hip group developed deep vein thrombosis during week 1. Conclusion THA through the Micro-hip approach achieved faster pain relief.