cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Superspace formulation of the Chern character of a theta-summable Fredholm module
Creators: name: Lesniewski, A.
name: Osterwalder, K.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We apply the concepts of superanalysis to present an intrinsically supersymmetric formulation of the Chern character in entire cyclic cohomology. We show that the cocycle condition is closely related to the invariance under supertranslations. Using the formalism of superfields, we find a path integral representation of the index of the generalized Dirac operator.
description: 10p, HUTMP B332
The Extended Supersymmetrization of the Nonlinear Schrodinger Equation
Creators: name: Popowicz, Ziemowit
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present the new extended supersymmetrization of the Nonlinear Schrodinger Equation by introducing two superbosons fields with the different gradation. Our model is different from this considered by Toppan and in the reduced case (nonextended supersymmetry) is also different from this considered by Kulish and Roelofs and Kersten. We prove that our model is integrable by presenting its Lax formulation.
description: e-mail ZIEMEK @ PLWRUW11.BITNET
$(1,q=-1)$ Model as a Topological Description of $2d$ String Theory
Creators: name: Lavi, Yoav
name: Oz, Yaron
name: Sonnenschein, Jacob
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the $(1,q=-1)$ model coupled to topological gravity as a candidate to describing $2d$ string theory at the self-dual radius. We define the model by analytical continuation of $q>1$ topological recursion relations to $q=-1$. We show that at genus zero the $q=-1$ recursion relations yield the $W_{1+\infty}$ Ward identities for tachyon correlators on the sphere. A scheme for computing correlation functions of $q=-1$ gravitational descendants is proposed and applied for the computation of several correlators. It is suggested that the latter correspond to correlators of discrete states of the $c=1$ string. In a similar manner to the $q>1$ models, we show that there exist topological recursion relations for the correlators in the $q=-1$ theory that consist of only one and two splittings of the Riemann surface. Using a postulated regularized contact, we prove that the genus one $q=-1$ recursion relations for tachyon correlators coincide with the $W_{1+\infty}$ Ward identities on the torus. We argue that the structure of these recursion relations coincides with that of the $W_{1+\infty}$ Ward identities for any genus.
description: 39 pages,latex,taup-2170 -94
Combined readout of a triple-GEM detector
Creators: name: Antochi, Vasile C.
name: Baracchini, Elisabetta
name: Cavoto, Gianluca
name: Di Marco, Emanuele
name: Marafini, Michela
name: Mazzitelli, Giovanni
name: Pinci, Davide
name: Renga, Francesco
name: Tomassini, Sandro
name: Voena, Cecilia
Publisher: name: arXiv
Year: 2018
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Optical readout of GEM based devices by means of high granularity and low noise CMOS sensors allows to obtain very interesting tracking performance. Space resolution of the order of tens of $μ$m were measured on the GEM plane along with an energy resolution of 20%$÷$30%. The main limitation of CMOS sensors is represented by their poor information about time structure of the event. In this paper, the use of a concurrent light readout by means of a suitable photomultiplier and the acquisition of the electric signal induced on the GEM electrode are exploited to provide the necessary timing informations. The analysis of the PMT waveform allows a 3D reconstruction of each single clusters with a resolution on z of 100 $μ$m. Moreover, from the PMT signals it is possible to obtain a fast reconstruction of the energy released within the detector with a resolution of the order of 25% even in the tens of keV range useful, for example, for triggering purpose.
description: 8 pages, 8 figures
The Nonlinear Multiplet Revisited
Creators: name: Kim, Byungbae
name: Lindström, Ulf
name: Roček, Martin
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Using a reformulation of the nonlinear multiplet as a gauge multiplet, we discuss its dynamics. We show that the nonlinear ``duality'' that appears to relate the model to a conventional $σ$-model introduces a new sector into the theory.
description: 11 pages, ITP-SB-94-23, USITP-94-10
On the networked architecture of genotype spaces and its critical effects on molecular evolution
Creators: name: Aguirre, Jacobo
name: Catalán, Pablo
name: Cuesta, José A.
name: Manrubia, Susanna
Publisher: name: arXiv
Year: 2018
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at the macroevolutionary, ecological, and molecular level. Actually, when the complex architecture of genotype spaces is taken into account, the evolutionary dynamics of molecular populations becomes intrinsically non-uniform, sharing deep qualitative and quantitative similarities with slowly driven physical systems: non-linear responses analogous to critical transitions, sudden state changes, or hysteresis, among others. Furthermore, the phenotypic plasticity inherent to genotypes transforms classical fitness landscapes into multiscapes where adaptation in response to an environmental change may be very fast. The quantitative nature of adaptive molecular processes is deeply dependent on a networks-of-networks multilayered structure of the map from genotype to function that we begin to unveil.
description: 48 pages, 4 figures
title: KLIMONAS-Ch05-A03 - Informations complémentaires relatives à l'entrée du bâtiment communautaire
title: KLIMONAS-Ch05-A03 – Supplementary information relating to the entrance of the Communal building
Creators: name: DELSOL, Nicolas
name: FRANEL, Yodrik
name: VIGNE, Jean-Denis
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: Appendix of: Vigne J.-D., Briois F., Guilaine J. (eds.), « Klimonas, an Early Pre-Pottery Neolithic village in Cyprus », Gallia Préhistoire & Paléorient, International Supplement 1, CNRS Éditions, Paris, 2023.
description: KLIMONAS-Ch05-A03 - Informations complémentaires relatives à l'entrée du bâtiment communautaire
Can hype be a force for good?
Creators: name: Roberson, Tara
Publisher: name: The Australian National University
Year: 2020

description: Hype takes the form of visions and stories, articulated through optimistic or pessimistic expectations. Visions of desirable futures to work towards, or undesirable futures to work against, help to motivate support for research and gather necessary resources, including funding and political capital. From research proposal through to commercialisation, science hype occurs at all stages of the research process. It is produced by all manner of science and technology actors as they imagine and invent technoscientific futures. To investigate the role of science hype in this thesis, I construct a conceptual framework that adopts research on sociotechnical imaginaries, anticipatory governance, and notions of convening publics. I use this framework to argue that hype is a communicative device that can spark unexpected engagement with science and technology futures. I test this framework using three cases studies in which hype is used to advance support for science and technology. In these case studies, hype helps shape the future of scientific research and technology development within the contexts of: human exploration of Mars; quantum-enabled technologies; and grand challenge-driven mandates for research. Hype, in a sense, prototypes those futures by establishing the viability and potential of the topic at hand. Within these case studies, hype is adopted to advance rhetoric concerned with competition, global leadership, and societal benefits. The events documented in these case studies affirm the ideal of science and technology ensuring progress and advancement. However, within the last case study, a different narrative emerges. This narrative suggests a new role for hype; one which draws on anticipatory governance. It opens the way for discussion on how hype might be repurposed in aid of science and technology that is created with, rather than for, society. In this scenario, the use of hype invites response, agreeable and otherwise, to potential shared futures.
Deciphering the Binding Mode and Mechanistic Insights of Pentadecylidenemalonate (1b) as Activator of Histone Acetyltransferase PCAF
Creators: name: Venkatesan Suryanarayanan
name: Singh, Sanjeev Kumar
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Histone acetyltransferases (HATs) is one among the conspicuous posttranslational modification in eukaryotic cells. p300/CBP Associated Factor (PCAF) and CREB-binding protein (CBP) are the two highly homologous HAT family which are vastly implicated in several diseases like cancer, diabetes etc. Pentadecylidenemalonate, a simplified analogue of anacardic acid, was reported as first mixed inhibitor/activator of HATs which inhibits p300/CBP and activates PCAF. It was appointed earlier as valuable biological tool to understand the mechanism of lysine acetyltransferases due to its powerful apoptotic effect. In this study, Pentadecylidenemalonate was taken for deciphering the binding mode, key interacting residues as well as mechanistic insights on PCAF and CBP as activator and inhibitor respectively. This study is highly believed to help in rational design on antineoplastic drugs against PCAF.
Syntheses and Nonlinear Optical Studies of Organoruthenium/Gold Nanoparticle Hybrids
Creators: name: Quintana Lopetegui, Cristobal
Publisher: name: The Australian National University
Year: 2020

description: Synthesis and Nonlinear Optical Studies of Organoruthenium/Gold Nanoparticle Hybrids Molecular and nano-materials that display nonlinear optical (NLO) processes like nonlinear absorption (NLA) processes have attracted considerable attention due to their potential applications in optical data storage, imaging, optical limiting, telecommunications, medicine, and 3D-patterning. We have extensively studied mono and bis alkynyl ruthenium phosphine complexes with outstanding NLA activity especially two photon (2PA) and multi-photon absorption (3PA and 4PA) in the visible to the near infrared spectrum. On the other hand plasmonic structures like gold nanoparticles are NLA active materials that can be employed to enhance a variety of optical and nonlinear optical processes due to strongly polarizable electrons of the localized surface plasmon resonance absorption band. In our search to develop novel and efficient NLA devices we investigated the properties of hybridized organoruthenium complexes and AuNPs. In this thesis project is discussed the different synthetic approaches that can be addressed to prepare a broad variety of novel surface functionalized AuNPs with organoruthenium complexes and their characterization, catalytic performance, optical properties and NLA performance. Molecular archetypes like rods, stars, branches and dendrimers were employed in this study to stabilize ultrasmall AuNPs. The hybrids were characterized comprehensively using various molecular and nanomaterial techniques never observed before in similar studies. It was found that the ruthenium complex (trans-Ru(dppe)2) is an essential component in the preparation of this new family of hybrids because it imparts good solubility and stability. More importantly the ruthenium complex/AuNP hybrids exhibit good transparency and exceptional NLA performance is observed for the linear- and star-shaped organoruthenium/AuNP hybrids.
Report of progress on the explorations and surveys up to January, 1874
Creators: name: Fleming, Sandford, 1827-1915
Publisher: name: Ottawa : MacLean, Roger & Co.
Year: 2015

description: "At head of title: Canadian Pacific Railway; Sandford Fleming, engineer-in-chief. Plates nos. 8, 10, 11, 13-16 in separate case. Appendices (contents in part): B. Peace River expedition, by C. Horetzky. - E. Progress report on the surveys for 1872 in British Columbia, by Marcus Smith. - G. Detail report of operations in the Rocky Mountains ... during the year 1872, by WaIter Moberly. - H. Detail report on the passes through the Cascade and year 1873, by Marcus Smith. - K. Special report on the passes through the Cascade and Rocky mountain chains, by Marcus Smith. - L. Extracts from report by Lieutenant H. Spencer Palmer, Royal Engineers, on the North Bentinck Arm and the route thence through the Cascade chain of mountains to the interior of British Columbia." -- Lowther, B. J., & Laing, M. (1968). A bibliography of British Columbia: Laying the foundations, 1849-1899. Victoria, BC: University of Victoria, p. 53.
Layer-wise synapse optimization for implementing neural networks on general neuromorphic architectures
Creators: name: Mern, John
name: Gupta, Jayesh K
name: Kochenderfer, Mykel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: Deep artificial neural networks (ANNs) can represent a wide range of complex functions. Implementing ANNs in Von Neumann computing systems, though, incurs a high energy cost due to the bottleneck created between CPU and memory. Implementation on neuromorphic systems may help to reduce energy demand. Conventional ANNs must be converted into equivalent Spiking Neural Networks (SNNs) in order to be deployed on neuromorphic chips. This paper presents a way to perform this translation. We map the ANN weights to SNN synapses layer-by-layer by forming a least-square-error approximation problem at each layer. An optimal set of synapse weights may then be found for a given choice of ANN activation function and SNN neuron. Using an appropriate constrained solver, we can generate SNNs compatible with digital, analog, or hybrid chip architectures. We present an optimal node pruning method to allow SNN layer sizes to be set by the designer. To illustrate this process, we convert three ANNs, including one convolutional network, to SNNs. In all three cases, a simple linear program solver was used. The experiments show that the resulting networks maintain agreement with the original ANN and excellent performance on the evaluation tasks. The networks were also reduced in size with little loss in task performance.
description: Submitted to IEEE Symposium Series on Computational Intelligence (SSCI) 2017
Complex Structures, Duality, and WZW-Models in Extended Superspace
Creators: name: Ivanov, Ivan T.
name: Kim, Byungbae
name: Rocek, Martin
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We find the complex structure on the dual of a complex target space. For $N=(2,2)$ systems, we prove that the space orthogonal to the kernel of the commutator of the left and right complex structures is {\em always} integrable, and hence the kernel is parametrized by chiral and twisted chiral superfield coordinates. We then analyze the particular case of $SU(2)\times SU(2)$, and are led to a new $N=2$ superspace formulation of the $SU(2)\times U(1)$ WZW-model.
description: Latex, 16 pages. In this revised manuscript, we add a section and an author, and alter one of the conclusions of the paper
3D-QSAR-aided design of potent c-Met inhibitors using molecular dynamics simulation and binding free energy calculation
Creators: name: Pavithra K. Balasubramanian
name: Balupuri, Anand
name: Swapnil P. Bhujbal
name: Cho, Seung Joo
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Abstract Mesenchymal-epithelial transition factor (c-Met) is a member of receptor tyrosine kinase. It involves in various cellular signaling pathways which includes proliferation, motility, migration, and invasion. Over-expression of c-Met has been reported in various cancers. Hence, it is an ideal therapeutic target for cancer. The main objective of the study is to identify crucial residues involved in the inhibition of c-Met kinase and to design a series of potent imidazo [4,5-b] pyrazine derivatives as c-Met inhibitors. Docking was used to identify important active site residues involved in the inhibition of c-Met kinase which was further validated by 100 ns of molecular dynamics simulation and free energy calculation using molecular mechanics generalized born surface area. Furthermore, binding energy decomposition identified that residues Tyr1230, Met1211, Asp1222, Tyr1159, Met1160, Val1092, Ala1108, and Leu1157 contributed favorably to the binding stability of compound 32. Receptor-guided Comparative Molecular Field Analysis (CoMFA) (q2 = 0.751, NOC = 6, r2 = 0.933) and Comparative Molecular Similarity Indices Analysis (COMSIA) (q2 = 0.744, NOC = 6, r2 = 0.950) models were generated based on the docked conformation of the most active compound 32. The robustness of these models was tested using various validation techniques and found to be predictive. The results of CoMFA and CoMSIA contour maps exposed the regions favorable to enhance the activity. Based on this information, 27 novel c-Met inhibitors were designed. These designed compounds exhibited potent activity than the most active compound of the existing dataset. Communicated by Ramaswamy H. Sarma
Algebraic structure of the Green's ansatz and its q-deformed analogue
Creators: name: Palev, T. D.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The algebraic structure of the Green's ansatz is analyzed in such a way that its generalization to the case of q-deformed para-Bose and para-Fermi operators is becoming evident. To this end the underlying Lie (super)algebraic properties of the parastatistics are essentially used.
description: plain TeX, Preprint INRNE-TH-94/4, 13 p
Stranger than fiction
Creators: name: Halcombe, J. J. (John Joseph)
Publisher: name: London : Society for Promoting Christian Knowledge
Year: 2015

description: "An account of Metlahkatla and the work of William Duncan. Third edition: 1873. Fourth edition: 1874. Also: 1877. Also: 1878. Also: 1880." -- Lowther, B. J., & Laing, M. (1968). A bibliography of British Columbia: Laying the foundations, 1849-1899. Victoria, BC: University of Victoria, p. 46.

"Published under the direction of the tract committee." -- Title page.
title: 01_0646
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Robust QSAR prediction models for volume of distribution at steady state in humans using relative distance measurements
Creators: name: I. Luque Ruiz
name: M. Á. Gómez-Nieto
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: The building of quantitative structure–activity relationship (QSAR) models for the in silico prediction of volume distribution for drugs at steady-state levels is vital for the selection of potential drugs at the synthesis stage. Using molecular descriptor matrixes, some regression models presenting low accuracy have been proposed, mainly due to the difficulty of compiling an appropriate dataset and the lack of information on dataset representation. In this paper, we use a benchmark dataset of very diverse drugs for the development of predictive models for volume distribution based on the use of relative distance matrixes as the input data to QSAR algorithms. Support vector machine, complex tree, bagged tree and Gaussian process regression algorithms were tested for fingerprint, similarity and relative distance matrixes used as input data, and the results of the built models were compared. Relative distance matrixes generated robust regression models in the training and external validation stages performed using cross-validation, obtaining values for correlation coefficient, bias, slope and root-mean-square error close to the ideal. Relative distance matrixes were also used for the design of classification models, obtaining excellent results with values of accuracy and area under receiver operating characteristic (AUC) close to 100%.
title: ADCO, Comptes du Petit-Cîteaux (1477-1491) (11 H 1179), f. 00622
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP

description: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179), f. 00622, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
On exact solutions and singularities in string theory
Creators: name: Horowitz, G. T.
name: Tseytlin, A. A.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct two new classes of exact solutions to string theory which are not of the standard plane wave or gauged WZW type. Many of these solutions have curvature singularities. The first class includes the fundamental string solution, for which the string coupling vanishes near the singularity. This suggests that the singularity may not be removed by quantum corrections. The second class consists of hybrids of plane wave and gauged WZW solutions. We discuss a four dimensional example in detail.
description: 45 pages, harvmac, Imperial/TP/93-94/38, NI94004 (minor corrections)
On the hierarchical structure of Pareto critical sets
Creators: name: Gebken, Bennet
name: Peitz, Sebastian
name: Dellnitz, Michael
Publisher: name: arXiv
Year: 2018
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: In this article we show that the boundary of the Pareto critical set of an unconstrained multiobjective optimization problem (MOP) consists of Pareto critical points of subproblems considering subsets of the objective functions. If the Pareto critical set is completely described by its boundary (e.g. if we have more objective functions than dimensions in the parameter space), this can be used to solve the MOP by solving a number of MOPs with fewer objective functions. If this is not the case, the results can still give insight into the structure of the Pareto critical set. This technique is especially useful for efficiently solving many-objective optimization problems by breaking them down into MOPs with a reduced number of objective functions.
Transverse noncommutative geometry of foliations
Creators: name: Benameur, Moulay-Tahar
name: Heitsch, James L.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 58H05, 46L80, 51P05

description: We define an $L^2$-signature for proper actions on spaces of leaves of transversely oriented foliations with bounded geometry. This is achieved by using the Connes fibration to reduce the problem to the case of Riemannian bifoliations where we show that any transversely elliptic first order operator in an appropriate Beals-Greiner calculus, satisfying the usual axioms, gives rise to a semi-finite spectral triple over the crossed product algebra of the foliation by the action, and hence a periodic cyclic cohomology class through the Connes-Chern character. The Connes-Moscovici hypoelliptic signature operator yields an example of such a triple and gives the differential definition of our "$L^2$-signature". For Galois coverings of bounded geometry foliations, we also define an Atiyah-Connes semi-finite spectral triple which generalizes to Riemannian bifoliations the Atiyah approach to the $L^2$-index theorem. The compatibility of the two spectral triples with respect to Morita equivalence is proven, and by using an Atiyah-type theorem proven in [BH17b], we deduce some integrality results for Riemannian foliations with torsion-free monodromy groupoids.
Western wanderings : a record of travel in the evening land : illustrated
Creators: name: Boddam-Whetham, J. W. (John Whetham), 1843-1918
Publisher: name: London : Richard Bentley and Son
Year: 2015

description: "Four chapters relate to Vancouver Island and mainland British Columbia." -- Lowther, B. J., & Laing, M. (1968). A bibliography of British Columbia: Laying the foundations, 1849-1899. Victoria, BC: University of Victoria, p. 52.
Curvature-dependent tension and tangential flows at the interface of motility-induced phases
Creators: name: Patch, Adam
name: Sussman, Daniel
name: Yllanes, David
name: Marchetti, M. Cristina
Publisher: name: arXiv
Year: 2018
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Purely repulsive active particles spontaneously undergo motility-induced phase separation (MIPS) into condensed and dilute phases. Remarkably, the mechanical tension measured along the interface between these phases is negative. In equilibrium this would imply an unstable interface that wants to expand, but these out-of-equilibrium systems display long-time stability and have intrinsically stiff boundaries. Here, we study this phenomenon in detail using active Brownian particle simulations and a novel frame of reference. By shifting from the global (or laboratory) frame to a local frame that follows the dynamics of the phase boundary, we observe correlations between the local curvature of the interface and the measured value of the tension. Importantly, our analysis reveals the presence of sustained local tangential motion of particles within a surface layer in both the gas and the dense regions. The combined tangential current in the gas and self-shearing of the surface of the dense phase suggest a stiffening interface that redirects particles along itself to heal local fluctuations. These currents restore the otherwise wildly fluctuating interface through an out-of-equilibrium Marangoni effect. We discuss the implications of our observations on phenomenological models of interfacial dynamics.
description: 10 pages, 9 figures
Gaussian approximation of the (2+1) dimensional Thirring model in the functional Schrödinger picture
Creators: name: Hyun, S. J.
name: Lee, G. H.
name: Yee, J. H.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The (2+1)-dimensional Thirring model is studied by using the Gaussian approximation method in the functional Schrödinger picture. Although the dynamical symmetry breaking does not occur in the large N limit, it does occur in the Gaussian approximation which includes the higher order contributions in 1/N.
description: 13 pages, YUMS 94-04 and SNUTP 94-44, revtex
title: ADCO, Cinquième cartulaire de Saint-Étienne de Dijon (1664), Cart. 28 (G 132), 258 folios, f. 00335
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00335, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00335, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
title: 02_0511
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
3D-QSAR-aided design of potent c-Met inhibitors using molecular dynamics simulation and binding free energy calculation.
Creators: name: Pavithra K. Balasubramanian
name: Balupuri, Anand
name: Swapnil P. Bhujbal
name: Cho, Seung Joo
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Mesenchymal-epithelial transition factor (c-Met) is a member of receptor tyrosine kinase (RTK). It involves in various cellular signaling pathways which includes proliferation, motility, migration and invasion. Over-expression of c-Met has been reported in various cancers. Hence, it is an ideal therapeutic target for cancer. The main objective of the study is to identify crucial residues involved in the inhibition of c-Met kinase and to design a series of potent imidazo [4,5-b] pyrazine derivatives as c-Met inhibitors. Docking was used to identify important active site residues involved in the inhibition of c-Met Kinase which was further validated by 100 ns of MD simulation and free energy calculation using MMGBSA. Furthermore, binding energy decomposition identified that residues Tyr1230, Met1211, Asp1222, Tyr1159, Met1160, Val1092, Ala1108, and Leu1157 contributed favorably to the binding stability of compound 32. Receptor-guided CoMFA (q2=0.751, NOC = 6, r2=0.933) and COMSIA (q2=0.744, NOC = 6, r2=0.950) models were generated based on the docked conformation of the most active compound 32. The robustness of these models was tested using various validation techniques and found to be predictive. The results of CoMFA and CoMSIA contour maps exposed the regions favorable to enhance the activity. Based on this information, 27 novel c-Met inhibitors were designed. These designed compounds exhibited potent activity than the most active compound of the existing dataset.
The dominion of Canada and the Canadian Pacific Railway
Creators: name: Wilson, William
Publisher: name: Victoria : Rose & Pottinger
Year: 2015

description: "An appeal for the railway's construction on the grounds of patriotism." -- Lowther, B. J., & Laing, M. (1968). A bibliography of British Columbia: Laying the foundations, 1849-1899. Victoria, BC: University of Victoria, p. 54.
Wave Functionals, Hamiltonians and Renormalization Group
Creators: name: Minic, D.
name: Nair, V. P.
Publisher: name: arXiv
Year: 1994
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We analyze the renormalization of wave functionals and energy eigenvalues in field theory. A discussion of the structure of the renormalization group equation for a general Hamiltonian system is also given.
description: 14, CCNY-HEP 5/94
Cloud Infrastructure Provenance Collection and Management to Reproduce Scientific Workflow Execution
Creators: name: Hasham, Khawar
name: Munir, Kamran
name: McClatchey, Richard
Publisher: name: arXiv
Year: 2018
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: The emergence of Cloud computing provides a new computing paradigm for scientific workflow execution. It provides dynamic, on-demand and scalable resources that enable the processing of complex workflow-based experiments. With the ever growing size of the experimental data and increasingly complex processing workflows, the need for reproducibility has also become essential. Provenance has been thought of a mechanism to verify a workflow and to provide workflow reproducibility. One of the obstacles in reproducing an experiment execution is the lack of information about the execution infrastructure in the collected provenance. This information becomes critical in the context of Cloud in which resources are provisioned on-demand and by specifying resource configurations. Therefore, a mechanism is required that enables capturing of infrastructure information along with the provenance of workflows executing on the Cloud to facilitate the re-creation of execution environment on the Cloud. This paper presents a framework, ReCAP, along with the proposed mapping approaches that aid in capturing the Cloud-aware provenance information and help in re-provisioning the execution resource on the Cloud with similar configurations. Experimental evaluation has shown the impact of different resource configurations on the workflow execution performance, therefore justifies the need for collecting such provenance information in the context of Cloud. The evaluation has also demonstrated that the proposed mapping approaches can capture Cloud information in various Cloud usage scenarios without causing performance overhead and can also enable the re-provisioning of resources on Cloud. Experiments were conducted using workflows from different scientific domains such as astronomy and neuroscience to demonstrate the applicability of this research for different workflows.
description: 59 pages, 21 figures, 4 algorithms, 6 tables, Future Generation Computer Systems. March 2018
The health and wellbeing of Aboriginal and Torres Strait Islander adolescents and young people: opportunities for applied epidemiology
Creators: name: Harfield, Stephen
Publisher: name: The Australian National University
Year: 2020

description: My MAE was undertaken at the South Australian Health and Medical Research Institute (SAHMRI), during 2018-2019. My studies focussed on the health and wellbeing of adolescent and young Aboriginal and Torres Strait Islander peoples, with the exception of my outbreak project. My studies included: Analysis of public health dataset - A retrospective study of South Australian adolescents aged 10-24 years utilising data from the Integrated South Australian Activity Collection dataset. The aim of the study was to assess leading causes and trends in hospital separations among adolescents in South Australia (SA) between 2006 and 2015, by sex, age groups and Aboriginal status. Counts and proportions of leading causes of separation were calculated as age-standardised rates and negative binominal regression was used to assess trend over time. Epidemiological study - Let's Talk About It 2019, an online survey of sexual health, knowledge, behaviours and access to health services for sexually transmitted infections (STI) and bloodborne viruses (BBV), amongst young South Australians aged 16-29 years, both Aboriginal and Torres Strait Islander and non-Indigenous. Descriptive analysis, univariate and adjusted logistic regression models were used to determine whether socio-demographic characteristics and sexual risk behaviours were associated with specific behaviours. Evaluation of a public health surveillance system - The preliminary evaluation of the ATLAS Aboriginal and Torres Strait Islander Sexual Health Surveillance Network - a national sentinel surveillance system within Aboriginal community-controlled health services (ACCHS). The evaluation of ATLAS involved a document review, stakeholder interviews and analysis of ATLAS data using the Centers for Disease Control and Prevention (United States of America) Updated Guidelines for Evaluating Public Health Surveillance Systems. I assessed the following attributes: acceptability, simplicity, flexibility, data quality, representativeness, timeliness, stability, and usefulness. Outbreak investigation - An epidemiological investigation and a retrospective case-control study of an outbreak of Salmonella Havana in alfalfa sprouts, in Adelaide. The outbreak was conducted during June and July 2018 with colleagues from SA Health. Investigations identified the most likely source to be alfalfa sprouts. Public health action lead to a consumer level recall of all alfalfa sprout products and public health alert. Teaching - This chapter outlines two teaching sessions, (i) a teaching session to first year MAE scholars, on a Single Overarching Communication Outcome (SOCO) in relation to the communication of a public health message; and (ii) a Lessons From the Field to my fellow scholars, on 'Conducting research with Aboriginal and Torres Strait Islander communities'.
Methodological developments in electron spin resonance (ESR) low-temperature thermochronometry
Creators: name: Fang, Fang
Publisher: name: The Australian National University
Year: 2020

description: Low-temperature thermochronometry provides a means of understanding the interaction between surface processes and underlying tectonics by quantifying the cooling histories of rocks. Electron spin resonance (ESR) thermochronometry works by determining the timing and rate at which electrons are trapped and thermally released in quartz in response to in situ ionizing radiation and rock cooling. This technique has great potential in reconstructing thermal histories of the upper ~ 2 km of the Earth's crust during the Quaternary. Its application, however, faces many challenges for methodological improvement since little work has been done on ESR thermochronometry after being first introduced in the late 1990s. Quantitative investigations of thermal histories by ESR thermochronometry rely on the determination of trap parameters of paramagnetic centres in quartz. This study has evaluated the activation energy and frequency factor of Al and Ti centres by analysing borehole samples with well-defined thermal histories and storage temperatures. Fergusons Hill-1 core is located at Otway Basin (Australia) where it is in a thermally steady state, while Eldzhurtinskiy Granite core is located in the Caucasus where it has experienced rapid cooling at a rate of ~ 520 degrees Celsius per million years. The best-fit parameters were determined by a first-order kinetic model which quantifies the irradiation-induced trapping and thermally-related detrapping processes. In heterogeneous rocks, numerical simulation is an ideal solution for accurate estimation of beta dose rate. Identification of mineral distribution is the basis for creating a model, and 2D mapping facilities are more effective than 3D X-ray computed tomography in this aspect. Thus, a 2D model "DosiVox-2D" was established for heterogeneous but isotropic samples, and verified by the comparison with the 3D model and infinite matrix dose method. The practical procedures were then investigated for applying 2D simulation on uniform and layered igneous rocks, including sample selection, mineral mapping, and estimation of radioelement concentrations. Thereafter, ESR thermochronometry was applied to Namche Barwa massif, the eastern Himalayan syntaxis. Samples were collected from a vertical transect to the south of the massif. ESR results, on one hand, have improved our understanding of the localised structural settings. On the other hand, the comparison of cooling history with the region adjacent to the north of the massif, has shed light on the domal development of Namche Barwa massif during Mid-late Pleistocene.
Designing potential HDAC3 inhibitors to improve memory and learning
Creators: name: Sk. Abdul Amin
name: Nilanjan Adhikari
name: Jha, Tarun
name: Balaram Ghosh
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology

description: The work presented here explores the structural and physicochemical features important for benzamide-based HDAC3 inhibitors to get an idea about the design aspect of potential inhibitors. A number of molecular modeling studies (3D-QSAR CoMFA and CoMSIA, Bayesian classification modeling) were performed on 113 diverse set of benzamide-based HDAC3 inhibitors. All these models developed are statistically reliable and correlate the SAR observations. Electron withdrawing substitution is favorable but the bulky hydrophobic group at the cap region reduces HDAC3 inhibition. Hydrophobicity and steric feature of the aryl linker function favor the activity. Aryl group substituted benzamide functionality is not favorable for HDAC3 inhibition. The amide function of the benzamide moiety is essential for Zn2+ chelation and the carboxylic acid function may serve as a hydrogen bond acceptor (HBA) feature. Moreover, electron withdrawing substituent at the benzamide moiety influences activity whereas steric and hydrophobic substituents reduce HDAC3 inhibition. Overall, this study may provide a valuable insight on the design of better active HDAC3 inhibitors in future. Communicated by Ramaswamy H. Sarma
Canada on the Pacific : being an account of a journey from Edmonton to the Pacific by the Peace River Valley; and of a winter voyage along the western coast of the dominion; with remarks on the physical features of the Pacific Railway route and notices of the Indian tribes of British Columbia
Creators: name: Horetzky, Charles, 1838-1900
Publisher: name: Montreal : Dawson Brothers
Year: 2015

description: "The writer organized and conducted the overland expedition of Mr. Sandford Fleming, from Fort Garry to Edmonton, during the summer of 1872; and it was at the instance of that gentleman, who desired to exhaust the whole field of enquiry, before deciding upon a route for the Canada Pacific road, that the journey ... was undertaken." -- Preface.