cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Limitations to Carrier Mobility and Phase-Coherent Transport in Bilayer Graphene
Creators: name: Engels, S.
name: Terrés, B.
name: Epping, A.
name: Khodkov, T.
name: Watanabe, K.
name: Taniguchi, T.
name: Beschoten, B.
name: Stampfer, C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present transport measurements on high-mobility bilayer graphene fully encapsulated in hexagonal boron nitride. We show two terminal quantum Hall effect measurements which exhibit full symmetry broken Landau levels at low magnetic fields. From weak localization measurements, we extract gate-tunable phase coherence times $τ_ϕ$ as well as the inter- and intra-valley scattering times $τ_i$ and $τ_*$. While $τ_ϕ$ is in qualitative agreement with an electron-electron interaction mediated dephasing mechanism, electron spin-flip scattering processes are limiting $τ_ϕ$ at low temperatures. The analysis of $τ_i$ and $τ_*$ points to local strain fluctuation as the most probable mechanism for limiting the mobility in high-quality bilayer graphene.
Anomalous discontinuity at the percolation critical point of active gels
Creators: name: Sheinman, M.
name: Sharma, A.
name: Alvarado, J.
name: Koenderink, G. H.
name: MacKintosh, F. C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We develop a percolation model motivated by recent experimental studies of gels with active network remodeling by molecular motors. This remodeling was found to lead to a critical state reminiscent of random percolation (RP), but with a cluster distribution inconsistent with RP. Our model not only can account for these experiments, but also exhibits an unusual type of mixed phase transition: We find that the transition is characterized by signatures of criticality, but with a discontinuity in the order parameter.
description: 8 pages, 5 figures
Power and Control in Platform Monopoly Capitalism
Creators: name: Pais, Ivana
name: Stark, David
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2022
Subjects: SPS/07 Sociologia generale
SPS/08 Sociologia dei processi culturali e comunicativi
SPS/09 Sociologia dei processi economici e del lavoro

description: This book is part of the Sociologica Curated series and brings together pieces previously published by Sociologica about the platform model. It includes: the Thematic Issue ‘Power and Control in Platform Monopoly Capitalism’ published in 14(3) 2021 together with the paper published by Watkins and Stark in 12(1) 2018 on the Möbius Organizational Form; Grabher & Konig’s ‘Disruption, Embedded: A Polanyian Framing of the Platform Economy’ published in 14 (1) 2020 and the related Symposium published in 14(3) 2021.
The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides
Creators: name: Seifert, Roland
name: Rosenthal, W.
name: Schultz, Günter
name: Wieland, T.
name: Gierschick, P.
name: Jakobs, K. H.
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: Adenine Nucleotides/pharmacology
subject: Adenosine Triphosphate/pharmacology
subject: Arachidonic Acid
subject: Arachidonic Acids/pharmacology
subject: Cell Line
subject: GTP-Binding Proteins/metabolism
subject: Guanine Nucleotides/pharmacology
subject: Guanosine 5'-O-(3-Thiotriphosphate)
subject: Guanosine Diphosphate/pharmacology
subject: Guanosine Triphosphate/pharmacology
subject: Humans
subject: Leukemia, Myeloid, Acute/metabolism
subject: NADH, NADPH Oxidoreductases/metabolism
subject: NADPH Oxidase
subject: Phosphotransferases/metabolism
subject: Superoxides/metabolism
subject: Thionucleotides/pharmacology

description: NADPH-oxidase-catalyzed superoxide (O2-) formation in membranes of HL-60 leukemic cells was activated by arachidonic acid in the presence of Mg2+ and HL-60 cytosol. The GTP analogues, guanosine 5'-[gamma-thio]triphosphate (GTP[gamma S] and guanosine 5'-[beta,gamma-imido]triphosphate, being potent activators of guanine-nucleotide-binding proteins (G proteins), stimulated O2- formation up to 3.5-fold. The adenine analogue of GTP[gamma S], adenosine 5'-[gamma-thio]triphosphate (ATP[gamma S]), which can serve as donor of thiophosphoryl groups in kinase-mediated reactions, stimulated O2- formation up to 2.5-fold, whereas the non-phosphorylating adenosine 5'-[beta,gamma-imido]triphosphate was inactive. The effect of ATP[gamma S] was half-maximal at a concentration of 2 microM, was observed in the absence of added GDP and occurred with a lag period two times longer than the one with GTP[gamma S]. HL-60 membranes exhibited nucleoside-diphosphate kinase activity, catalyzing the thiophosphorylation of GDP to GTP[gamma S] by ATP[gamma S]. GTP[gamma S] formation was half-maximal at a concentration of 3-4 microM ATP[gamma S] and was suppressed by removal of GDP by creatine kinase/creatine phosphate (CK/CP). The stimulatory effect of ATP[gamma S] on O2- formation was abolished by the nucleoside-diphosphate kinase inhibitor UDP. Mg2+ chelation with EDTA and removal of endogenous GDP by CK/CP abolished NADPH oxidase activation by ATP[gamma S] and considerably diminished stimulation by GTP[gamma S]. GTP[gamma S] also served as a thiophosphoryl group donor to GDP, with an even higher efficiency than ATP[gamma S]. Transthiophosphorylation of GDP to GTP[gamma S] was only partially inhibited by CK/CP. Our results suggest that NADPH oxidase is regulated by a G protein, which may be activated either by exchange of bound GDP by guanosine triphosphate or by thiophosphoryl group transfer to endogenous GDP by nucleoside-diphosphate kinase.
Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4
Creators: name: Schmidt, H. H.
name: Seifert, Roland
name: Böhme, E.
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: Bucladesine/pharmacology
subject: Calcitriol/pharmacology
subject: Canavanine/pharmacology
subject: Cell Line
subject: Humans
subject: Kinetics
subject: Leukemia, Promyelocytic, Acute
subject: Leukotriene B4/pharmacology
subject: Luminescence
subject: N-Formylmethionine Leucyl-Phenylalanine/pharmacology
subject: Neutrophils/metabolism
subject: Nitric Oxide/metabolism
subject: Platelet Activating Factor/pharmacology

description: Vascular endothelial cells and neutrophils synthesize and release potent vasodilatatory factors, i.e. endothelium-derived relaxing factors (EDRF) and neutrophil-derived relaxing factors (NDRF). One EDRF has been identified as nitric oxide (NO) derived from arginine. We studied the synthesis and release of NO from human neutrophils stimulated with the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine, platelet activating factor or leukotriene B4. The formation and release of NO was enhanced several-fold in the presence of superoxide dismutase, probably by inhibiting superoxide-induced breakdown of NO. The formation and release of NO but not the formation of superoxide anions was decreased in neutrophils pretreated with L-canavanine, an inhibitor of arginine-utilizing enzymes. Our data suggest that at least one NDRF is identical with NO or another labile NO containing compound derived from arginine.
Doing Social Sciences via Comics and Graphic Novels
Creators: name: Barberis, Eduardo
name: Gruning, Barbara
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2022
Subjects: SPS/07 Sociologia generale
SPS/08 Sociologia dei processi culturali e comunicativi

description: Visual communication is far from new and is almost as old as the social sciences. In the last decades, the interest in the visual dimension of society as well as towards the visual as expression of local and global cultures increased to the extent that specific disciplinary approaches took root --- e.g. visual anthropology and visual sociology. Nevertheless, it seems to us that whereas they are mostly engaged in collecting visual data and analyzing visual cultural products, little attention is paid to one of the original uses of visual material in ethnographic and social research, that is communicating social sciences. Departing from some general questions, such as how visualizing sociological concepts, what role non-textual stimuli play in sociology, how they differentiate according to the kind of public, and how we can critically and reflexively assess the social and disciplinary implications of visualizations of empirical research, we collect in the special issues contributions from social scientists and comics artists who materially engaged in the production of social sciences via comics and graphic narratives. The article is divided into three parts. Firstly, we briefly address the rollercoaster history of encounters between sociology and the sequential art. Secondly, we reconstruct the dynamics and processes which lead to the institutionalization of a transnational field of comics studies. Finally, we introduce the contributions collected in the special issue, based on the persona experiences of social scientists, sometimes in collaboration with illustrators.
Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol
Creators: name: Seifert, Roland
name: Schächtele, C.
name: Rosenthal, W.
name: Schultz, Günter
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: Animals
subject: Brain/enzymology
subject: Calcium/pharmacology
subject: Diglycerides/pharmacology
subject: Enzyme Activation
subject: Fatty Acids, Unsaturated/pharmacology
subject: Glycerides/pharmacology
subject: Kinetics
subject: Protein Kinase C/metabolism
subject: Rats
subject: Stereoisomerism
subject: Structure-Activity Relationship

description: Both cis- and trans-unsaturated but not saturated fatty acids activated protein kinase C purified to apparent homogeneity from rat brain. Fatty-acid-induced enzyme activation was not more than additive with that by phospholipids and was potentiated by diacylglycerol. Recently, we demonstrated that cis- and trans-unsaturated fatty acids induced platelet aggregation and phosphorylation of specific proteins. Both events were potentiated by a cell-permeable diacylglycerol [(1987) Biochem. Biophys. Res. Commun. 149, 762-768]. Thus, trans-unsaturated fatty acids may provide useful experimental tools for the study of protein kinase C activation in vitro and in vivo. Our results suggest that fatty acids and diacylglycerol may synergistically be involved in hormonal stimulation of protein kinase C, as certain hormonal stimuli cause release of diacylglycerol and fatty acids from phospholipids by parallel activation of phospholipases C and A2.
Bicrossed Products, Matched Pair Deformations and the Factorization Index for Lie Algebras
Creators: name: Agore, Ana-Loredana
name: Militaru, Gigel
Publisher: name: arXiv
Year: 2013
Subjects: subject: Rings and Algebras (math.RA)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: For a perfect Lie algebra $\mathfrak{h}$ we classify all Lie algebras containing $\mathfrak{h}$ as a subalgebra of codimension $1$. The automorphism groups of such Lie algebras are fully determined as subgroups of the semidirect product $\mathfrak{h} \ltimes (k^* \times {\rm Aut}_{\rm Lie} (\mathfrak{h}))$. In the non-perfect case the classification of these Lie algebras is a difficult task. Let $\mathfrak{l} (2n+1, k)$ be the Lie algebra with the bracket $[E_i, G] = E_i$, $[G, F_i] = F_i$, for all $i = 1, \dots, n$. We explicitly describe all Lie algebras containing $\mathfrak{l} (2n+1, k)$ as a subalgebra of codimension $1$ by computing all possible bicrossed products $k \bowtie \mathfrak{l} (2n+1, k)$. They are parameterized by a set of matrices ${\rm M}_n (k)^4 \times k^{2n+2}$ which are explicitly determined. Several matched pair deformations of $\mathfrak{l} (2n+1, k)$ are described in order to compute the factorization index of some extensions of the type $k \subset k \bowtie \mathfrak{l} (2n+1, k)$. We provide an example of such extension having an infinite factorization index.
SN1987A cooling due to Plasmon-Plasmon scattering in the Randall-Sundrum Model
Creators: name: Sharma, Manish Kumar
name: Kundu, Saumyen
name: Das, Prasanta Kumar
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The light braneworld radion, stabilized via the Goldberger-Wise mechanism in the Randall-Sundrum model, can be produced copiously inside the supernova core due to plasmon-plasmon annihilations. The radion, thus produced, subsequently decays to a neutrino-antineutrino pair and takes away the energy released in the SN1987A explosion. Assuming that the supernovae cooling rate for any new physics channel(Raffelt's criterion) $\dot{\varepsilon}(γ_Pγ_P \stackrelϕ{\longrightarrow} ν_τ \overlineν_τ) \leq 7.288\times 10^{-27} \rm{GeV}$, we find the lower bound on the radion vacuum expectation value $\langleϕ\rangle \sim 3$~TeV for $m_ϕ= 30$ MeV corresponding to the deformation parameter $q=1.17$ in the Tsallis statistics formalism. In the scenario with $q=1$, we find $\langleϕ\rangle = 178$ GeV for $m_ϕ= 30$ MeV.
description: 13 pages, 3 figures
Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine
Creators: name: Schächtele, C.
name: Seifert, Roland
name: Osswald, H.
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
subject: Alkaloids/pharmacology
subject: Diglycerides/pharmacology
subject: Humans
subject: Isoquinolines/pharmacology
subject: Linoleic Acid
subject: Linoleic Acids/pharmacology
subject: Male
subject: Piperazines/pharmacology
subject: Platelet Aggregation/drug effects
subject: Platelet Aggregation Inhibitors/pharmacology
subject: Polymyxin B/pharmacology
subject: Polymyxins/pharmacology
subject: Protein Kinase C/antagonists & inhibitors
subject: Staurosporine
subject: Thrombin/pharmacology

description: Thrombin, 1-oleoyl-2-acetyl-rac-glycerol (OAG), cis- or trans-octadecadienoic acids (linoleic and linolelaidic acid) and the synergistic combination of octadecadienoic acids plus OAG lead to the activation of gel-filtered human platelets, i.e. aggregation via protein kinase C (PKC). Platelet activation by thrombin was only slightly suppressed by polymyxin B, 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) or staurosporine, all being potent inhibitors of PKC in vitro. The OAG-induced aggregation, however, was strongly inhibited by H-7 or staurosporine but not by polymyxin B. In contrast, octadecadienoic acid-induced aggregation was substantially inhibited only by polymyxin B. Synergistic activation by OAG plus octadecadienoic acids was strongly suppressed by all three PKC inhibitors. Our results indicate (1) that the ability of various compounds to inhibit PKC in vitro does not correlate with their inhibitory effects in intact cells and (2) that platelet activation induced by various PKC activators exhibits differential PKC-inhibitor sensitivity.
Dirac equation in low dimensions: The factorization method
Creators: name: Sanchez-Monroy, J. A.
name: Quimbay, C. J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a general approach to solve the (1+1) and (2+1)-dimensional Dirac equation in the presence of static scalar, pseudoscalar and gauge potentials, for the case in which the potentials have the same functional form and thus the factorization method can be applied. We show that the presence of electric potentials in the Dirac equation leads to a two Klein-Gordon equations including an energy-dependent potential. We then generalize the factorization method for the case of energy-dependent Hamiltonians. Additionally, the shape invariance is generalized for a specific class of energy-dependent Hamiltonians. We also present a condition for the absence of the Klein's paradox (stability of the Dirac sea), showing how Dirac particles in low dimensions can be confined for a wide family of potentials.
description: 24 pages, 4 references added, types corrected
Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol
Creators: name: Seifert, Roland
name: Schächtele, C.
name: Schultz, Günter
Publisher: name: Universität Regensburg
Year: 1987
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: Blood Platelets/enzymology
subject: Diglycerides/pharmacology
subject: Enzyme Activation/drug effects
subject: Glycerides/pharmacology
subject: Humans
subject: Phosphorylation
subject: Platelet Aggregation/drug effects
subject: Protein Kinase C/analysis
subject: Proteins/metabolism
subject: Stearic Acids/pharmacology

description: Octadecadienoic acids (linoleic acid and linolelaidic acid) and the diacylglycerol, 1-oleoyl-2-acetyl-rac-glycerol (OAG) concentration-dependently induced activation of gel-filtered human platelets, i.e. aggregation and phosphorylation of 20 kDa and 47 kDa peptides. In contrast, octadecenoic acids (oleic and elaidic acid) and octadecanoic (stearic) acid were inactive. Octadecadienoic acid-induced platelet activation was suppressed by the protein kinase C inhibitor, polymyxin B, but not by the cyclooxygenase inhibitor, indomethacin. OAG-induced activation was potentiated by octadecadienoic acids present at non-stimulatory concentrations. Our data suggest that octadecadienoic acids and diacylglycerol synergistically induce platelet activation via protein kinase C. Furthermore, linolelaidic acid may provide a useful experimental tool to study fatty acid regulation of protein kinase C in intact cells.
The Horseshoe Estimator: Posterior Concentration around Nearly Black Vectors
Creators: name: van der Pas, S. L.
name: Kleijn, B. J. K.
name: van der Vaart, A. W.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: 62F15, 62F10

description: We consider the horseshoe estimator due to Carvalho, Polson and Scott (2010) for the multivariate normal mean model in the situation that the mean vector is sparse in the nearly black sense. We assume the frequentist framework where the data is generated according to a fixed mean vector. We show that if the number of nonzero parameters of the mean vector is known, the horseshoe estimator attains the minimax $\ell_2$ risk, possibly up to a multiplicative constant. We provide conditions under which the horseshoe estimator combined with an empirical Bayes estimate of the number of nonzero means still yields the minimax risk. We furthermore prove an upper bound on the rate of contraction of the posterior distribution around the horseshoe estimator, and a lower bound on the posterior variance. These bounds indicate that the posterior distribution of the horseshoe prior may be more informative than that of other one-component priors, including the Lasso.
description: This version differs from the final published version in pagination and typographical detail; Available at http://projecteuclid.org/euclid.ejs/1418134265
EVALUATION AND ADJUSTMENT OF INFRASTRUCTURE LEAKAGE INDEX FOR TOWNS IN DEVELOPING COUNTRIES
Creators: name: Zede
Publisher: name: Zede Journal of Ethiopian Engineers and Architects
Year: 2024

description: Evaluating water loss and the performance of urban water supply utilities is critical. The objective of this research was to evaluate the applicability of the Infrastructure Leakage Index (ILI) formula for towns of developing countries and suggest adjustment factors.Basic water supply data from nine towns of Ethiopia was used to calculate ILI and develop modification factors. Water supply development level factor was determined based on the actual water production and optimal consumption if there was sufficient supply. Asset management factor was developed considering the categorization of Ethiopian towns which was related to expected water supply level based on development level. The study showed the Unavoidable Annual Real Loss (UARL) formula gave similar values for any type of water supply system whether developed or not. Except for Addis Ababa, the calculated ILIs utilizing the standard formula were less than four indicating unrealistic very good performance. Applying the adjustment factors, realistic ILI values were obtained reflecting the realistic performance of water utilities in developing countries, requiring timely appropriate water loss reduction measures.
description: Zede Journal of Ethiopian Engineers and Architects, Vol. 42 (2024): Zede Journal of Ethiopian Engineers and Architects
Role of BRICS in the Development of participating nations
Creators: name: ., MGMulla
Publisher: name: figshare
Year: 2023
Subjects: Industrial and employee relations
Workforce planning
Business and labour history
Finance

description: The developing countries were the main stages providing FDI inflow in world economy in 2012. The shares of BRICS countries in the total inflow of the current world FDI increased to 11% in 2011.
Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase
Creators: name: Seifert, Roland
name: Schächtele, C.
Publisher: name: Universität Regensburg
Year: 1988
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
subject: Cytochalasin B/pharmacology
subject: Enzyme Activation/drug effects
subject: Female
subject: Humans
subject: Isoquinolines/pharmacology
subject: Male
subject: N-Formylmethionine Leucyl-Phenylalanine/pharmacology
subject: NADH, NADPH Oxidoreductases/metabolism
subject: Neutrophils/enzymology
subject: Piperazines/pharmacology
subject: Protein Kinase C/physiology
subject: Superoxides/metabolism
subject: Tetradecanoylphorbol Acetate/pharmacology
subject: Tumor Cells, Cultured

description: The effects of various protein kinase C (PKC) inhibitors on NADPH oxidase (NO) activation by the phorbol ester PMA and by the chemotactic peptide FMLP were studied. H-7 reduced the effects of both stimuli in human neutrophils (HN) and HL-60 cells by 13-63%. Polymyxin B did not inhibit NO activation by PMA and FMLP in HN and reduced the effects of both stimuli in HL-60 cells by 27-55%. Retinal and retinoic acid enhanced the effects of PMA and FMLP in HL-60 cells and of FMLP in HN up to 4.5-fold. In contrast, retinoic acid inhibited the effect of PMA in HN. In the presence of cytochalasin B, retinal inhibited the effect of FMLP in HN, whereas retinoic acid inhibited NO activation by FMLP in both cell types. The dual PKC/calmodulin inhibitors trifluoperazine and W-7 abolished NO activation by PMA and FMLP in HN and HL-60 cells. Thus, the effects of PKC inhibitors on NO activation exhibit (1) cell type specificity, (2) stimulus dependency and (3) no correlation with in vitro inhibition of PKC. Our results suggest that studies with PKC inhibitors presently available cannot clarify the role of PKC in NO activation.
Explaining the Performance of Collaborative Filtering Methods With Optimal Data Characteristics
Creators: name: Poudel, Samin
name: Bikdash, Marwan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Information Retrieval (cs.IR)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The performance of a Collaborative Filtering (CF) method is based on the properties of a User-Item Rating Matrix (URM). And the properties or Rating Data Characteristics (RDC) of a URM are constantly changing. Recent studies significantly explained the variation in the performances of CF methods resulted due to the change in URM using six or more RDC. Here, we found that the significant proportion of variation in the performances of different CF techniques can be accounted to two RDC only. The two RDC are the number of ratings per user or Information per User (IpU) and the number of ratings per item or Information per Item (IpI). And the performances of CF algorithms are quadratic to IpU (or IpI) for a square URM. The findings of this study are based on seven well-established CF methods and three popular public recommender datasets: 1M MovieLens, 25M MovieLens, and Yahoo! Music Rating datasets
COMPARATIVE ASSESSMENT OF THE EFFECTS OF PLANT BASED GUMS ON RHEOLOGICAL CHARACTERISTICS OF MAIZE DOUGH AND ITS BREAD QUALITY
Creators: name: Zede
Publisher: name: Zede Journal of Ethiopian Engineers and Architects
Year: 2024

description: Bread made from maize is considered as gluten free and thus recommended for people living with celiac disease. However, bread made from maize has inferior quality when compared to bread made from wheat. The aim of this investigation was to explore how plant-based gums affect the rheological attributes of dough made from maize flour and the resulting bread quality. Various types of plant gums were use data ratio of 3% to the flour weight basis. Control samples were prepared using maize and wheat flours. To provide a basis for comparison, dough and bread samples made from wheat flour were also used. The study examined the farinographic, pasting,gaseous release and dough development characteristics. Proximate composition, loaf  specific volumes, texture character, and sensory qualities of bread were also examined. The inclusion of gums in maize flour reduced the dough's water absorption capacity (WAC) and degree of softening(DS). Treatment with gums also had a considerable impact on most of the pasting profile. Furthermore, treatment with gums improved bread loaf weight and specific volumes. The firmness of the maize bread was higher than the maize bread prepared from the dough samples treated with gums.
description: Zede Journal of Ethiopian Engineers and Architects, Vol. 42 (2024): Zede Journal of Ethiopian Engineers and Architects
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells
Creators: name: Seifert, Roland
name: Jungblut, P.
name: Schultz, Günter
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: Arachidonic Acid
subject: Arachidonic Acids/pharmacology
subject: Bucladesine/pharmacology
subject: Calcimycin/pharmacology
subject: Cell Differentiation/drug effects
subject: Cell Line
subject: Cytosol/physiology
subject: Dimethyl Sulfoxide/pharmacology
subject: Enzyme Activation
subject: Guanosine 5'-O-(3-Thiotriphosphate)
subject: Guanosine Triphosphate/pharmacology
subject: Humans
subject: Kinetics
subject: Leukemia, Promyelocytic, Acute
subject: Lindane/pharmacology
subject: N-Formylmethionine Leucyl-Phenylalanine/pharmacology
subject: NADH, NADPH Oxidoreductases/metabolism
subject: NADPH Oxidase
subject: Superoxides/metabolism
subject: Tetradecanoylphorbol Acetate/pharmacology
subject: Thionucleotides/pharmacology

description: Activation of NADPH oxidase in undifferentiated HL-60 leukemic cells and in HL-60 cells differentiated along the myeloid pathway with dibutyryl cyclic AMP (dbcAMP) or dimethyl sulfoxide (Me2SO) was studied. Upon stimulation with a calcium ionophore, a phorbol ester, arachidonic acid or gamma-hexachlorocyclohexane, Me2SO-differentiated HL-60 cells generated superoxide (O2-) at higher rates than dbcAMP-differentiated cells. Undifferentiated cells generated O2- only at low rates upon stimulation with the above agents. In cell-free systems, NADPH oxidase activity was reconstituted by combining membranes of undifferentiated or dbcAMP- or Me2SO-differentiated HL-60 cells, cytosol of Me2SO-differentiated cells and arachidonic acid. This basal O2- formation was enhanced several-fold by guanosine 5'-O-(3-thiotriphosphate) (GTP[gamma S]), a potent activator of guanine nucleotide-binding proteins. In contrast, cytosol of dbcAMP-differentiated cells reconstituted O2- formation only in the presence of GTP[gamma S], and cytosol of undifferentiated cells was inactive. Submaximally stimulatory amounts of cytosolic protein of Me2SO- and dbcAMP-differentiated cells synergistically stimulated O2- formation in the presence but not in the absence of GTP[gamma S]. We conclude that differentiations of HL-60 cells with Me2SO and dbcAMP are not equivalent with respect to activation of NADPH oxidase and that two cytosolic activation factors are involved in the regulation of this effector system.
Heating Cold Clumps by Jet-inflated Bubbles in Cooling Flow Clusters
Creators: name: Hillel, Shlomi
name: Soker, Noam
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We simulate the evolution of dense-cool clumps embedded in the intra-cluster medium (ICM) of cooling flow clusters of galaxies in response to multiple jet-activity cycles, and find that the main heating process of the clumps is mixing with the hot shocked jets' gas, the bubbles, while shocks have a limited role. We use the PLUTO hydrodynamical code in two dimensions with imposed axisymmetry, to follow the thermal evolution of the clumps. We find that the inflation process of hot bubbles, that appear as X-ray deficient cavities in observations, is accompanied by complicated induced vortices inside and around the bubbles. The vorticity induces efficient mixing of the hot bubbles' gas with the ICM and cool clumps, resulting in a substantial increase of the temperature and entropy of the clumps. For the parameters used by us heating by shocks barely competes with radiative cooling, even after 25 consecutive shocks excited during 0.5 Gyr of simulation. Some clumps are shaped to filamentary structure that can turn to observed optical filaments. We find that not all clumps are heated. Those that cool to very low temperatures will fall in and feed the central supermassive black hole (SMBH), hence closing the feedback cycle in what is termed the cold feedback mechanism.
description: Accepted by MNRAS
From haloes to Galaxies - I. The dynamics of the gas regulator model and the implied cosmic sSFR history
Creators: name: Peng, Yingjie
name: Maiolino, Roberto
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We explore the basic parameters that drive the evolution of the fundamental properties of star forming galaxies within the gas regulator model, or bathtub-model. We derive the general analytic form of the evolution of the key galaxy properties, i.e. gas mass, star formation rate (SFR), stellar mass, specific SFR, gas fraction, gas phase metallicity and stellar metallicity, without assuming that galaxies live in the equilibrium state. We find that the timescale required to reach equilibrium, tau_eq, which is determined by the product of star-formation efficiency and mass-loading factor, is the central parameter that is essentially in control of the evolution of all key galaxy properties. The scatters in most of the key scaling relations, such as the mass-SFR relation and mass-metallicity relation, are primarily governed by tau_eq. Most strikingly, the predicted sSFR evolution is controlled solely by tau_eq (apart from the cosmic time). Although the precise evolution of the sSFR depends on tau_eq, the sSFR history is largely insensitive to different values of tau_eq. The difference between the minimum and maximum sSFR at any epoch is less than a factor of four. The shape of the predicted sSFR history simply mimics that of the specific mass increase rate of the dark matter halos (sMIR_DM) with the typical value of the sSFR around 2*sMIR_DM, in good agreement with the predictions from typical Semi-Analytic Models (SAMs), but both are fundamentally different from the observed sSFR history. This clearly implies that some key process is missing in both typical SAMs and gas regulator model, and we hint at some possible culprit. We emphasize the critical role of tau_eq in controlling the evolution of the galaxy population, especially for gas rich low mass galaxies that are very unlikely to live around the equilibrium state at any epoch and this has been largely ignored in many similar studies.
description: MNRAS. Accepted 2014 June 25. Received 2014 June 23; in original form 2014 February 25
Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides
Creators: name: Seifert, Roland
name: Schultz, Günter
Publisher: name: Universität Regensburg
Year: 1989
Subjects: subject: 610 Medizin
subject: 615 Pharmazie
subject: Animals
subject: Cell Physiological Phenomena
subject: Humans
subject: Pyrimidines/metabolism
subject: Uracil Nucleotides/physiology
subject: Uridine/physiology

description: Uridine and uracil nucleotides are involved in the regulation of various cell functions. Here, Roland Seifert and Günter Schultz review the evidence that, rather than by binding to purinoceptors, pyrimidine nucleotides exert their effects by binding to distinct pyrimidinoceptors, which are coupled to pertussis toxin-sensitive G proteins in human phagocytes. However, many questions remain to be answered: no antagonists for these pyrimidinoceptors are available, and binding studies have not been carried out; the receptor proteins and subtypes have not been characterized; and little is known about the G proteins and effector systems involved, or the regulation of storage and release of pyrimidine nucleotides.
The adhesion model as a field theory for cosmological clustering
Creators: name: Rigopoulos, Gerasimos
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The adhesion model has been proposed in the past as an improvement of the Zel'dovich approximation, providing a good description of the formation of the cosmic web. We recast the model as a field theory for cosmological large scale structure, adding a stochastic force to account for power generated from very short, highly non-linear scales that is uncorrelated with the initial power spectrum. The dynamics of this Stochastic Adhesion Model (SAM) is reminiscent of the well known Kardar-Parisi-Zhang equation with the difference that the viscosity and the noise spectrum are time dependent. Choosing the viscosity proportional to the growth factor $D$ restricts the form of noise spectrum through a 1-loop renormalization argument. For this choice, the SAM field theory is renormalizable to one loop. We comment on the suitability of this model for describing the non-linear regime of the CDM power spectrum and its utility as a relatively simple approach to cosmological clustering.
description: 10 pages, 2 figures; v2: 11 pages, 2 figures, minor modifications and addition of references, version accepted in JCAP
PERFORMANCE ENHANCEMENT OF KALITY WASTEWATER TREATMENT PLANT’S UP FLOW ANAEROBIC SLUDGE BLANKET REACTOR USING SURFACE RESPONSE METHODS
Creators: name: Zede
Publisher: name: Zede Journal of Ethiopian Engineers and Architects
Year: 2024

description: The main aim of this study was to examine and optimize the performance of anaerobic sludge blanket reactor (UASB) using the surface response method-central composite design (RSM-CCD). The influences of several operational parameters were considered, including temperature (0 to 30°C), organic loading rate (OLR) (1 to 3 kg COD/m3·d), pH (6.3 to 7.8), and hydraulic retention time (HRT) (4 to 12h). The pilotscale reactor had a volume of 48.8 L. The RSM-CCD was used for the determination of the number of runs and the optimization of operational parameters. According to the derived model, the reactor exhibited optimal results under the following conditions: Temperature (23.0°C), OLR (2.3 kg COD/m3·d), pH (7.5), and HRT (11.4h).  Removals of 84.1%, 99.9%, and 100% for chemical oxygen demand (COD), total
description: Zede Journal of Ethiopian Engineers and Architects, Vol. 42 (2024): Zede Journal of Ethiopian Engineers and Architects
On the thermodynamic stability of rotating black holes in higher dimensions -- a comparison of thermodynamic ensembles
Creators: name: Dolan, Brian P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Thermodynamic potentials relevant to the micro-canonical, the canonical and the grand-canonical ensembles, associated with rotating black holes in D-dimensions, are analysed and compared. Such black holes are known to be thermodynamically unstable, but the instability is a consequence of a subtle interplay between specific heats and the moments of inertia and it manifests itself differently in the different ensembles. A simple relation between the product of the specific heat and the determinant of the moment of inertia in both the canonical and the grand-canonical ensembles is derived. Myers-Perry black holes in arbitrary dimension are studied in detail. All temperature extrema in the micro-canonical ensemble are determined and classified. The specific heat and the moment of inertia tensor are evaluated in both the canonical and the grand-canonical ensembles in any dimension. All zeros and poles of the specific heats, as a function of the angular momenta, are determined and the eigenvalues of the isentropic moment of inertia tensor are also found and classified. It is further shown that many of the thermodynamic properties of a Myers-Perry black hole in D-2 dimensions can be obtained from those of a black hole in D dimensions by sending one of the angular momenta to infinity.
description: 41 pages, 5 figures; typo in appendix D corrected in v4
The Impact of High Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review with Methodological, Clinical, and Mechanistic Implications
Creators: name: Funaro, Melissa
name: Petrakis, Ismene
name: Muvvala, Srinivas
name: Caldwell, Ebony
name: De Aquino, Joao P.
name: Jegede, Oluwole
name: Hsaio, Connie
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Mental and Social Health
subject: Substance Abuse and Addiction
subject: Medicine and Health Sciences

description: This is a protocol for the scoping review of the impact of High Potency synthetic opioids on pharmacotherapies for Opioid use disorders
Eudaimonic career identities – Finnish executive women’s career navigation at the top management level
Creators: name: Poso, Anita
Publisher: name: University of Westminster
Year: 2023

description: Even in one of the most gender-equal countries in the world, Finland, the share of women in executive business roles has remained at less than 20%. This thesis examines the career identities of executive women in business-related roles in large companies in Finland. A model of eudaimonic career identities was built to understand the enablers of executive women’s career navigation and success. The data were collected through a pilot study consisting of 133 interviews with women and in-depth interviews with 17 Finnish women executives. The research questions the validity of current career models by explaining executive women’s career progression to the top organisational level. This research integrates a missing element—the concept of eudaimonia—into a career identity model, which comprises the enablers of executive careers. The findings suggest how executive women’s career identities are constructed on eudaimonic values instead of objective career success measures, including status, money and power. Moreover, the research challenges the approaches of systematic career planning and position-based career goals as the enablers of career progression. The research findings evidence three types of career patterns leading to the top management team (TMT) level: conventional linear careers and moderate and frequent boundaryless moves. However, executive women were not hindered by the typical barriers that boundaryless career theories suggest that women leaders specifically encounter. The career patterns demonstrate the need for meaningful work, the possibility to influence and continuous challenges, which increase the women’s competence in the executive leader role while accepting new positions within or outside the current employer. Demonstrated excellency in leading people and extensive business understanding, which is acquired often through finance and accounting experience or knowledge, were perceived as imperative enablers of a successful executive career. Additionally, agency, risk-taking and decision-making skills were seen vital career resources. As an academic contribution, this research contests the incongruence of leader and gender roles suggested by the social role theory. The women executives effortlessly demonstrated both stereotypically masculine and feminine traits and behaviours in their leader role identities, without emphasising or compromising their womanness. Moreover, the concept of authenticity operates as a discursive bridge between the gender and leader roles, resonating with eudaimonic aspirations. This research assists professionals and leaders of all genders to aim for excellence and authenticity in their pursuit of meaningful career experiences.
Anomalous sequence of quantum Hall liquids revealing tunable Lifshitz transition in bilayer graphene
Creators: name: Varlet, Anastasia
name: Bischoff, Dominik
name: Simonet, Pauline
name: Watanabe, Kenji
name: Taniguchi, Takashi
name: Ihn, Thomas
name: Ensslin, Klaus
name: Mucha-Kruczynski, Marcin
name: Fal'ko, Vladimir I.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Fermi surface topology plays an important role in determining the electronic properties of metals. In bulk metals, the Fermi energy is not easily tunable at the energy scale needed for reaching conditions for the Lifshitz transition - a singular point in the band structure where the connectivity of the Fermi surface changes. Bilayer graphene is a unique system where both Fermi energy and the low-energy electron dispersion can be tuned using the interplay between trigonal warping and a band gap opened by a transverse electric field. Here, we drive the Lifshitz transition to experimentally controllable carrier densities by applying large transverse electric fields through a h-BN-encapsulated bilayer graphene structure, and detect it by measuring the degeneracies of Landau levels. These degeneracies are revealed by filling factor -3 and -6 quantum Hall effect states of holes at low magnetic fields reflecting the existence of three maxima on the top of the valence band dispersion. At high magnetic fields all integer quantum Hall states are observed, indicating that deeper in the valence band the constant energy contours are singly-connected. The fact that we observe ferromagnetic quantum Hall states at odd-integer filling factors testifies to the high quality of our sample, and this enables us to identify several phase transitions between correlated quantum Hall states at intermediate magnetic fields, in agreement with the calculated evolution of the Landau level spectrum.
description: 5 pages, 3 figures
THE PERFORMANCE OF PRIVATE RESIDENTIAL REAL ESTATE DEVELOPERS IN ETHIOPIA: THE CASE OF ADDIS ABABA
Creators: name: Zede
Publisher: name: Zede Journal of Ethiopian Engineers and Architects
Year: 2024

description: The issue of providing adequate housing tothe general public is critical in both developed and developing nations. This requires continuous monitoring of performance in the provision of housing as a fundamental approach to enhance efficiency and establish a strategic framework for achieving better productivity. This study focuses on the performance evaluation of real estate firms in Addis Ababa and identifies the obstacles encountered that would influence their construction operations and management. The primary goal of this research is to introduce the concept of project performance, identify the factors influencing performance and propose strategies for enhancing performance in real estate firms. The qualitative research methodology employed involved non-random sampling. The methodology involved preliminary investigation and a pilot study, to refine and explore the research areas. Through the data analysis process; the study underscored the significance of focusing on customer satisfaction, cost overruns and other financial aspects when considering performance metrics. Furthermore, among the factors impacting performance; material price fluctuations, exchange rate variations and construction material shortages ranked highest in their order of appearance. The study's findings culminate in essential recommendations for improvement strategies. In conclusion, it emphasizes the necessity of a collaborative effort among all stakeholders to notably elevate the real estate sector.
description: Zede Journal of Ethiopian Engineers and Architects, Vol. 42 (2024): Zede Journal of Ethiopian Engineers and Architects
Mimetic dark matter, ghost instability and a mimetic tensor-vector-scalar gravity
Creators: name: Chaichian, Masud
name: Kluson, Josef
name: Oksanen, Markku
name: Tureanu, Anca
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Recently modified gravitational theories which mimic the behaviour of dark matter, the so-called "Mimetic Dark Matter", have been proposed. We study the consistency of such theories with respect to the absence of ghost instability and propose a new tensor-vector-scalar theory of gravity, which is a generalization of the previous models of mimetic dark matter with additional desirable features. The original model proposed by Chamseddine and Mukhanov [JHEP 1311 (2013) 135, arXiv:1308.5410] is concluded to describe a regular pressureless dust, presuming that we consider only those configurations where the energy density of the mimetic dust remains positive under time evolution. For certain type of configurations the theory can become unstable. Both alternative modified theories of gravity, which are based on a vector field (tensor-vector theory) or a vector field and a scalar field (tensor-vector-scalar theory), are free of ghost instabilities.
description: 23 pages, v4: clarifies and/or extends the discussion on the positivity of total energy, the instability found in the original mimetic model, and the number of physical degrees of freedom in each considered theory. Presentation improved in section 3. To be published in J. High Energy Phys