cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones
Creators: name: Patterson, Cam
name: Marques, Carla
name: Guo, Weimin
name: Pereira, Paulo
name: Evans, Paul C.
name: Taylor, Allen
name: Shang, Fu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Accumulation of damaged proteins is causally related to many age-related diseases. The ubiquitin-proteasome pathway (UPP) plays a role in selective degradation of damaged proteins, whereas molecular chaperones, such as heat shock proteins, are involved in refolding denatured proteins. This work demonstrates for the first time that the UPP and molecular chaperones work in a competitive manner and that the fates of denatured proteins are determined by the relative activities of the UPP and molecular chaperones. Enhanced UPP activity suppresses the refolding of denatured proteins whereas elevated chaperone activity inhibits the degradation of denatured proteins. CHIP, a co-chaperone with E3 activity, plays a pivotal role in determining the fates of the damaged proteins. The delicate balance between UPP-mediated degradation and refolding of denatured proteins is governed by relative levels of CHIP and other molecular chaperones. Isopeptidases, the enzymes that reverse the actions of CHIP, also play an important role in determining the fate of denatured proteins.
Predicting repurposed drugs targeting the NS3 protease of dengue virus using machine learning-based QSAR, molecular docking, and molecular dynamics simulations
Creators: name: Chongjun, Y.
name: Nasr, A.M.S.
name: Latif, M.A.M.
name: Rahman, M.B.A.
name: Marlisah, E.
name: Tejo, B.A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer
Virology

description: Dengue fever, prevalent in Southeast Asian countries, currently lacks effective pharmaceutical interventions for virus replication control. This study employs a strategy that combines machine learning (ML)-based quantitative-structure-activity relationship (QSAR), molecular docking, and molecular dynamics simulations to discover potential inhibitors of the NS3 protease of the dengue virus. We used nine molecular fingerprints from PaDEL to extract features from the NS3 protease dataset of dengue virus type 2 in the ChEMBL database. Feature selection was achieved through the low variance threshold, F-Score, and recursive feature elimination (RFE) methods. Our investigation employed three ML models – support vector machine (SVM), random forest (RF), and extreme gradient boosting (XGBoost) – for classifier development. Our SVM model, combined with SVM-RFE, had the best accuracy (0.866) and ROC_AUC (0.964) in the testing set. We identified potent inhibitors on the basis of the optimal classifier probabilities and docking binding affinities. SHAP and LIME analyses highlighted the significant molecular fingerprints (e.g. ExtFP69, ExtFP362, ExtFP576) involved in NS3 protease inhibitory activity. Molecular dynamics simulations indicated that amphotericin B exhibited the highest binding energy of −212 kJ/mol and formed a hydrogen bond with the critical residue Ser196. This approach enhances NS3 protease inhibitor identification and expedites the discovery of dengue therapeutics.
Choline metabolism and risk of breast cancer in a population-based study
Creators: name: Wetmur, James G.
name: Chen, Jia
name: Lee, Yin Leng
name: Zeisel, Steven H.
name: Gammon, Marilie D.
name: Bradshaw, Patrick T.
name: Xu, Xinran
name: Neugut, Alfred I.
name: Santella, Regina M.
name: Teitelbaum, Susan L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Choline is an essential nutrient required for methyl group metabolism, but its role in carcinogenesis and tumor progression is not well understood. By utilizing a population-based study of 1508 cases and 1556 controls, we investigated the associations of dietary intake of choline and two related micronutrients, methionine and betaine, and risk of breast cancer. The highest quintile of choline consumption was associated with a lower risk of breast cancer [odds ratio (OR): 0.76; 95% confidence interval (CI): 0.58−1.00] compared with the lowest quintile. Two putatively functional single nucleotide polymorphisms of cholinemetabolizing genes, PEMT −774G>C (rs12325817) and CHDH +432G>T (rs12676), were also found be related to breast cancer risk. Compared with the PEMT GG genotype, the variant CC genotype was associated with an increased risk of breast cancer (OR: 1.30; 95% CI: 1.01−1.67). The CHDH minor T allele was also associated with an increased risk (OR: 1.19; 95% CI: 1.00−1.41) compared with the major G allele. The BHMT rs3733890 polymorphism was also examined but was found not to be associated with breast cancer risk. We observed a significant interaction between dietary betaine intake and the PEMT rs7926 polymorphism (Pinteraction=0.04). Our findings suggest that choline metabolism may play an important role in breast cancer etiology.—Xu, X., Gammon, M. D., Zeisel, S. H., Lee, Y. L., Wetmur, J. G., Teitelbaum, S. L., Bradshaw, P. T., Neugut, A. I., Santella, R. M., Chen, J. Choline metabolism and risk of breast cancer in a population-based study.
On the number of edges in a graph with no $(k+1)$-connected subgraphs
Creators: name: Bernshteyn, Anton
name: Kostochka, Alexandr
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C35, 05C40

description: Mader proved that for $k\geq 2$ and $n\geq 2k$, every $n$-vertex graph with no $(k+1)$-connected subgraphs has at most $(1+\frac{1}{\sqrt{2}})k(n-k)$ edges. He also conjectured that for $n$ large with respect to $k$, every such graph has at most $\frac{3}{2}\left(k - \frac{1}{3}\right)(n-k)$ edges. Yuster improved Mader's upper bound to $\frac{193}{120}k(n-k)$ for $n\geq\frac{9k}{4}$. In this note, we make the next step towards Mader's Conjecture: we improve Yuster's bound to $\frac{19}{12}k(n-k)$ for $n\geq\frac{5k}{2}$.
description: 8 pages; a few typos have been fixed
Engineered proteins with Pumilio/ fem-3 mRNA binding factor scaffold to manipulate RNA metabolism
Creators: name: Tanaka Hall, Traci M.
name: Wang, Zefeng
name: Wang, Yang
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Pumilio/fem-3 mRNA binding factor (FBF) proteins are characterized by a sequence-specific RNA-binding domain. This unique single-stranded RNA recognition module, whose sequence specificity can be reprogrammed, has been fused with functional modules to engineer protein factors with various functions. Here we summarize the advancement in developing RNA regulatory tools and opportunities for the future.
Neutralizing the anticoagulant activity of ultra-low-molecular-weight heparins using N -acetylglucosamine 6-sulfatase
Creators: name: Linhardt, Robert J.
name: Li, Lingyun
name: Liu, Jian
name: Zhou, Xianxuan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Heparin has been the most commonly used anticoagulant drug for nearly a century. The drug heparin is generally categorized into three forms according to its molecular weight (MW), unfractionated (UF, average MW 13,000), low molecular weight (LMW, average MW 5,000), and ultra-low molecular weight heparin (ULMWH, average MW 2,000). Overdose of anticoagulant heparin can lead to very dangerous bleeding in patients. Protamine sulfate can be administered as an antidote to reverse heparin’s anticoagulant effect. There is not an effective antidote for ULMWH. In the current study, we examine human N-acetylglucosamine 6-sulfatase (NG6S), expressed in Chinese hamster ovary cells as a reversal agent for ULMWH. NG6S removes a single 6-O-sulfo group at the non-reducing end of the ULMWH Arixtra® (fondaparinux) effectively removing its ability to bind to antithrombin and preventing its inhibition of coagulation factor Xa. These results pave the way to develop human NG6S as an antidote for neutralizing the anticoagulant activity of ULMWHs.
Table S1; Table S2 from An adaptable but threatened big cat: density, diet and prey selection of the Indochinese leopard (Panthera pardus delacouri) in eastern Cambodia.
Creators: name: Rostro-García, Susana
name: Kamler, Jan F.
name: Crouthers, Rachel
name: Keo Sopheak
name: Sovanna Prum
name: Visattha In
name: Chanratana Pin
name: Caragiulo, Anthony
name: Macdonald, David W.
Publisher: name: The Royal Society
Year: 2019
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Summaries from Maximum-likelihood spatially explicit capture-recapture models using different buffer width to estimate leopard density during 2014 in Srepok Wildlife Sanctuary, Cambodia.; Posterior summaries from Bayesian spatially explicit capture-recapture models used to estimate leopard density during 2014 in Srepok Wildlife Sanctuary, Cambodia.
Making Sense of Qualitative and Quantitative Findings in Mixed Research Synthesis Studies
Creators: name: Barroso, Julie
name: Hasselblad, Victor
name: Sandelowski, Margarete
name: Voils, Corrine I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The synthesis of qualitative and quantitative research findings is increasingly promoted, but many of the conceptual and methodological issues it raises have yet to be fully understood and resolved. In this article, we describe how we handled issues encountered in efforts to synthesize the findings in forty-two reports of studies of antiretroviral adherence in HIV-positive women in the course of an ongoing study to develop methods to synthesize qualitative and quantitative research findings in common domains of health-related research. Working with these reports underscored the importance of looking past method claims and ideals and directly at the findings themselves, differentiating between aggregative syntheses in which findings are assimilated and interpretive syntheses in which they are configured, and understanding the judgments involved in designating relationships between findings as confirmatory, divergent, or complementary.
Physiotherapy management of functional movement disorders: the patient perspective
Creators: name: Zeun, Debbie
name: Hunter, Heather
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Mental Health

description: People with functional movement disorders (FMD) are commonly seen in neurology clinics. Despite a recent increase in research, no standardised treatment pathway across the UK exists. Currently only a few qualitative studies in FMD with a focus on psychological aspects and diagnosis have been published. This study aimed to understand people with FMD perceptions of their physiotherapy treatment. Qualitative web-based interviews were conducted with seven participants and an interpretive phenomenological approach was used to identify themes from the data. Four themes were identified; 1) my brain, mind and body are all me, 2) physiotherapy; what helps and what doesn’t, 3) what recovery is to me, and 4) barriers to treatment. Participants desired a combination of psychological and physical approaches, which were holistic, individualised, and delivered by experienced physiotherapists. Limited availability and funding of specialist treatments were barriers to recovery. Holistic management combining psychological and physiological systems seems to be crucial for effective management of FMD. Large variations in physiotherapy treatment exist across the UK. It is hoped that increasing the understanding, amongst healthcare professionals will lead to the development of timely and appropriate pathways for patients that otherwise find themselves lost between medical specialities.IMPLICATIONS FOR REHABILITATIONPatients report more positive experiences when a combined and detailed psychological and physiological explanation to their symptoms is given.An individualised approach working with the patient on activities they find challenging is more preferable than group exercise or impairment based (e.g., strengthening/stretching) treatments.Having a physiotherapist who is experienced in treating functional movement disorders or prepared to learn and understand them helped with adherence to treatment. Patients report more positive experiences when a combined and detailed psychological and physiological explanation to their symptoms is given. An individualised approach working with the patient on activities they find challenging is more preferable than group exercise or impairment based (e.g., strengthening/stretching) treatments. Having a physiotherapist who is experienced in treating functional movement disorders or prepared to learn and understand them helped with adherence to treatment.
title: Diagnostic Value of Dynamic Magnetic Resonance Imaging with Diffusion Weighted Imaging in the Staging of Endometrial Carcinoma
Creators: name: Khoroushi, Farzane
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Genital / Reproductive system female
subject: MR
subject: Colonography MR
subject: Biological effects

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Endometrial carcinoma is the most common cancer of the female genital system and reportedly accounts for 20% to 30% of female genital tract malignancies (1). The prognosis and survival rate of endometrial cancer patients depend on a series of...
(400770) James Thomson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Infection control in COVID-19 computed tomography outpatient triage centers. 2 years of deployment
Creators: name: Berezin, Nikita
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Emergency
subject: Lung
subject: CT
subject: Safety
subject: Technical aspects
subject: Epidemiology
subject: Infection
subject: Workforce

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: To discuss evolution of infection control principles for staff and patients' safety in outpatient triage centres during SARS-CoV-19...
(400765) Jessie McArthur
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Spontaneous instabilities and stick-slip motion in a generalized Hebraud-Lequeux model
Creators: name: Bouchaud, Jean-Philippe
name: Gualdi, Stanislao
name: Tarzia, Marco
name: Zamponi, Francesco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We revisit the Hébraud-Lequeux (HL) model for the rheology of jammed materials and argue that a possibly important time scale is missing from HL's initial specification. We show that our generalization of the HL model undergoes interesting oscillating instabilities for a wide range of parameters, which lead to intermittent, stick-slip flows under constant shear rate. The instability we find is akin to the synchronization transition of coupled elements that arises in many different contexts (neurons, fireflies, financial bankruptcies, etc.). We hope that our scenario could shed light on the commonly observed intermittent, serrated flows of glassy materials under shear.
description: 9 pages, 3 figures
title: An analysis of brain structures volume in pediatric patients with epilepsy.
Creators: name: Wozniak, Magdalena
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Paediatric
subject: MR
subject: Computer Applications-Detection, diagnosis
subject: Seizure disorders

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Epilepsy is one of the most frequent serious brain disorders. Approximately 30,000 of the 150,000 children and adolescents who experience unprovoked seizures are diagnosed with epilepsy each year Magnetic resonance imaging is the method of choice in...
(400767) Margaret Mcarthur
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The suffragette movement in H.G. Wells’s Ann Veronica and May Sinclair’s The Tree of Heaven
Creators: name: Pudełko, Brygida
Publisher: name: Polilog. Studia Neofilologiczne
Year: 2016

description: The suffragette movement in H.G. Wells’s Ann Veronica and May Sinclair’s The Tree of Heaven In H.G. Wells’s Ann Veronica (1909), the eponymous heroine embraces new womanhood and a range of feminisms in her search for life. Ann Veronica attends suffrage and other radical meetings in London once she has left her father and home in order to “live”. She is arrested during a raid on the House of Commons, while trying to defend an elderly suffragette. However, the harshness of prison life forces Ann Veronica to see the error of her ways and to seek a reconciliation with her father upon her release. Here, militant suffragism is portrayed as a turning point. It is a reaction that brings down all the powers of patriarchy upon her and causes her to accept “life” as it is rather than seek to change it. May Sinclair’s 1917 novel The Tree of Heaven explores the key issues of the early twentieth century: feminism, modern art, technology and sexual freedom. All represent danger for the growing Harrison children, Dorothea, Michael and Nicholas. Dorothea is fascinated with suffragism and feminism, yet, like Sinclair herself, she also fears it. She approves of the idea, but is sceptical about the militant suffragism. Both Ann Veronica and Dorothea Harrison regard the Vote as only one point in a wide programme for the elevation of their sex. They have no clear conception of the new position of women in society, but are much disappointed to find that the prominent suffragettes have in reality no grasp of the profound changes that are taking places in the relationship between the sexes, nor of how little the Vote itself means. They are equally disappointed as Wells and Sinclair were.
description: Polilog. Studia Neofilologiczne, No. 6 (2016): Polylogue. Neophilological Studies
title: Spectrum of Ompahloceles and Why All Omphalocele Minors Are Not Always Minor!
Creators: name: Bagchi, Shramana
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Abdomen
subject: Foetal imaging
subject: Ultrasound
subject: Ultrasound-Colour Doppler
subject: Intrauterine diagnosis
subject: Foetus
subject: Hernia

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Ompahlocele is a midline anterior ody wall defect , associated with underlying chromosomal abnormalities in 50- 70 % of the cases, so prenatal diagnosis holds unique importance for reduction of the post natal morbidity . The sac is covered (inside...
Using Participatory Mapping to Inform a Community-Randomized Trial of HIV Counseling and Testing
Creators: name: Ntogwisangu, Jacob
name: Visrutaratna, Surasing
name: Fritz, Katherine
name: Modiba, Precious
name: Lane, Tim
name: Timbe, Andrew
name: Vanrooyen, Heidi
name: Maman, Suzanne
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Participatory mapping and transect walks were used to inform the research and intervention design and to begin building community relations in preparation for Project Accept, a community-randomized trial sponsored by the U.S. National Institute of Mental Health (NIMH). NIMH Project Accept is being conducted in five sites within four countries including Thailand, Zimbabwe, South Africa and Tanzania. Results from the mapping exercises informed decisions about the research design such as defining community boundaries, and identifying appropriate criteria for matching community pairs for the trial. The mapping also informed intervention related decisions such as where to situate the services. The participatory methods enabled each site to develop an understanding of the communities that could not have been derived from existing data or data collected through standard data collection techniques. Furthermore, the methods lay the foundation for collaborative community research partnerships.
Child and Family Characteristics Influencing Intervention Choices in Autism Spectrum Disorders
Creators: name: Schultz, Beth
name: Patten, Elena
name: Watson, Linda R.
name: Baranek, Grace T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: A myriad of treatment options are available for children with autism, yet little is understood regarding characteristics of parents (e.g., education) and children (e.g., severity of autism symptoms) that influence types and amounts of therapy utilization. Interviews from 70 families were analyzed to determine potential influences on utilization (e.g., start of first services, use of traditional services). Descriptive findings regarding therapy types were similar to national studies. However, only three of the variables predicted utilization of specific therapies: severity of sensory processing problems was associated with earlier initiation of services in general, and higher maternal and paternal education was associated with the use of dietary and/or vitamin therapy as well as with more types of services. No other variables had predictive value; thus, the amount and type of therapies received may be more related to diagnostic practices and/or to the affordances/constraints of service delivery and reimbursement systems at particular ages.
Gradient optimization of analytic controls: the route to high accuracy quantum optimal control
Creators: name: Machnes, Shai
name: Assémat, Elie
name: Tannor, David J.
name: Wilhelm, Frank K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum computation places very stringent demands on gate fidelities, and experimental implementations require both the controls and the resultant dynamics to conform to hardware-specific constraints. Superconducting qubits present the additional requirement that pulses must have simple parameterizations, so they can be further calibrated in the experiment, to compensate for uncertainties in system parameters. Other quantum technologies, such as sensing, require extremely high fidelities. We present a novel, conceptually simple and easy-to-implement gradient-based optimal control technique named Gradient Optimization of Analytic conTrols (GOAT), which satisfies all the above requirements, unlike previous approaches. To demonstrate GOAT's capabilities, with emphasis on flexibility and ease of subsequent calibration, we optimize fast coherence-limited pulses for two leading superconducting qubits architectures - flux-tunable transmons and fixed-frequency transmons with tunable couplers.
Taking the Bitter with the Sweet: Relationship of Supertasting and Sweet Preference with Metabolic Syndrome and Dietary Intake: Sweet preference and dietary intake …
Creators: name: Turner-McGrievy, Gabrielle
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Results examining the effects of tasting profile on dietary intake and health outcomes have varied. This study examined the interaction of sweet liker (SL) and supertasting (ST) (bitter taste test through phenylthiocarbamide (PTC)) status with incidence of metabolic syndrome.
The appearance of the 1989 political transformation in Central European prose
Creators: name: Németh, Zoltán
Publisher: name: Polilog. Studia Neofilologiczne
Year: 2016

description: The appearance of the 1989 political transformation in Central European prose The study is interpreting the common experiences of (Eastern) Central European literatures, whose common factors are the dictatorship lasting over forty years, 1989 as the turning point, and the post-communist era. I analyse the following Czech, Slovak, Polish, Hungarian and Slovak Hungarian books: Dorota Masłowska Wojna polsko-ruska pod flagą biało-czerwoną (Polish-Russian war under the white and red flag) (2002), Jáchym Topol Anděl (Angel) (1995), Eman Erdélyi, Marek Vadas Univerzita (University) (1996), Oliver Bakoš Katedra paupológie (The Paupology Department) (2001), Attila Györy Kitörés (Breaking out) (1993), János Térey Termann hagyományai (Termann’s Traditions) (1997) and Attila Hazai Szex a nappaliban (Sex in the Living Room) (2000). The theoretical boom of the 90s and the new, determining Central-Eastern-European status of theory is a common experience in Eastern-Central-European literary theory and literature. Another great experience of post-89 Eastern-Central-European prose is travelling and the meeting of cultures. The topos of being en route seems essential in the European novel, and most often, the stages of the protagonist’s development are linked to the sections of the road travelled. In post-1989 Eastern-Central European prose, drugs are major referential candidates. Drugs became part of the post-89 folklore; for the societies awakening behind the iron curtain, especially for the young generations, they are identified with freedom or, more precisely, with its anarchistic concept. The study analyses the common socio-cultural characteristics in the post-89 Eastern-Central-European prose.
description: Polilog. Studia Neofilologiczne, No. 6 (2016): Polylogue. Neophilological Studies
(400763) James M McArthur
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Neuro epidemiology of stroke in southwest Ethiopia; Our Exsperiance following the introduction of the first CT Scanner
Creators: name: Dibaba, Abdi
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: CT
subject: Education
subject: Epidemiology
subject: Haemorrhage

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Cardiovascular disease is the primary global cause of death, responsible for more than 17.3 million deaths annually, and according to data gathered from the Global Burden of Diseases (GBD), the number is projected to exceed 23.6 million by 2030....
Foot Disorders Associated With Overpronated and Oversupinated Foot Function: The Johnston County Osteoarthritis Project
Creators: name: Hillstrom, Howard J.
name: Jordan, Joanne M.
name: Golightly, Yvonne M.
name: Dufour, Alyssa B.
name: Hannan, Marian T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The occurrence of musculoskeletal foot disorders differs by race and obesity, and these disorders may be related to pronated (low arch) or supinated (high arch) foot function. This cross-sectional analysis examined relationships of foot disorders and foot function by race and obesity in a community-based observational study of adults 50+ years old with and without osteoarthritis.
(400764) Janet Powrie McArthur
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Patients experience of cognitive fatigue post-stroke: an exploratory study
Creators: name: Askari, Sorayya
name: Harvey, Keri
name: Sam-Odutola, Mary
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: Cognitive fatigue is commonly reported and described as disabling by patients recovering from neurological conditions including stroke. However, cognitive fatigue is usually underdiagnosed among stroke survivors which leads to a lack of specific treatments for this condition. Therefore, the aim of this study was to explore post-stroke cognitive fatigue as it is experienced by stroke survivors. This qualitative research followed the principles of descriptive phenomenology within a constructivist paradigm. Individual semi-structured interviews were conducted with stroke survivors experiencing post-stroke cognitive fatigue recruited through the Heart and Stroke Foundation, the Canadian Partnership for Stroke Recovery, and social media posts. Data were analyzed through inductive content analysis. Eleven stroke survivors participated. The analysis revealed five themes illustrating the experience and descriptions of post-stroke cognitive fatigue: (1) characteristics, (2) aggravating factors, (3) management, (4) effect of cognitive fatigue on daily life, and (5) social awareness and support. This study highlights the complexity of post-stroke cognitive fatigue. Cognitive fatigue becomes more evident after discharge; therefore, clinicians should consistently screen for it and provide proper education to the patients and their carers.IMPLICATIONS FOR REHABILITATIONCognitive fatigue is a complex phenomenon that can negatively affect the daily life of stroke survivors.Sensory-overloaded environments, emotional distress, poor sleep, and engaging in complex cognitive tasks can trigger post-stroke cognitive fatigue.More education on the concept of cognitive fatigue should be provided to healthcare providers to be able to identify and manage this symptom properly. Cognitive fatigue is a complex phenomenon that can negatively affect the daily life of stroke survivors. Sensory-overloaded environments, emotional distress, poor sleep, and engaging in complex cognitive tasks can trigger post-stroke cognitive fatigue. More education on the concept of cognitive fatigue should be provided to healthcare providers to be able to identify and manage this symptom properly.
title: A Convolutional Neural Network Model For Screening Breast Lesions by Mammography Using A Small Dataset
Creators: name: Goyal, Swati
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Breast
subject: Oncology
subject: Mammography
subject: Computer Applications-Detection, diagnosis
subject: Education
subject: Image verification
subject: Neoplasia
subject: Outcomes

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Breast carcinoma is a concerning health problem worldwide, usually affecting females aged more than forty, and has exceeded lung malignancy as the world’s most frequently diagnosed cancer. According to the American Cancer Society, approximately...
A generalized Lieb-Liniger model
Creators: name: Veksler, Hagar
name: Fishman, Shmuel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In 1963, Lieb and Liniger solved exactly a one dimensional model of bosons interacting by a repulsive δ-potential and calculated the ground state in the thermodynamic limit. In the present work, we extend this model to a potential of three δ-functions, one of them is repulsive and the other two are attractive, modeling some aspects of the interaction between atoms, and present an approximate solution for a dilute gas. In this limit, for low energy states, the results are found to be reduced to the ones of an effective Lieb Liniger model with an effective δ-function of strength $c_{eff}$ and the regime of stability is identified. This may shed light on some aspects of interacting bosons.
description: 13 pages, 2 figures
(400766) Robert Mcarthur
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Table S1; Table S2 from An adaptable but threatened big cat: density, diet and prey selection of the Indochinese leopard (Panthera pardus delacouri) in eastern Cambodia
Creators: name: Rostro-García, Susana
name: Kamler, Jan F.
name: Crouthers, Rachel
name: Keo Sopheak
name: Sovanna Prum
name: Visattha In
name: Chanratana Pin
name: Caragiulo, Anthony
name: Macdonald, David W.
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Summaries from Maximum-likelihood spatially explicit capture-recapture models using different buffer width to estimate leopard density during 2014 in Srepok Wildlife Sanctuary, Cambodia.; Posterior summaries from Bayesian spatially explicit capture-recapture models used to estimate leopard density during 2014 in Srepok Wildlife Sanctuary, Cambodia.
Contribution of Gut Bacteria to Liver Pathobiology
Creators: name: Kremer, Michael
name: Hines, Ian N.
name: Son, Gakuhei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Emerging evidence suggests a strong interaction between the gut microbiota and health and disease. The interactions of the gut microbiota and the liver have only recently been investigated in detail. Receiving approximately 70% of its blood supply from the intestinal venous outflow, the liver represents the first line of defense against gut-derived antigens and is equipped with a broad array of immune cells (i.e., macrophages, lymphocytes, natural killer cells, and dendritic cells) to accomplish this function. In the setting of tissue injury, whereby the liver is otherwise damaged (e.g., viral infection, toxin exposure, ischemic tissue damage, etc.), these same immune cell populations and their interactions with the infiltrating gut bacteria likely contribute to and promote these pathologies. The following paper will highlight recent studies investigating the relationship between the gut microbiota, liver biology, and pathobiology. Defining these connections will likely provide new targets for therapy or prevention of a wide variety of acute and chronic liver pathologies.
เล่าเรื่องคดีแพ่ง : สภาพบังคับทางกฎหมายของข้อสัญญาว่าจะไม่นอกใจ
Creators: name: ภรณี เกราะแก้ว
Publisher: name: สำนักวิชานิติศาสตร์ มหาวิทยาลัยแม่ฟ้าหลวง
Year: 2567
Subjects: หลักอิสระทางแพ่ง
เสรีภาพในการทำสัญญา
ข้อสัญญาว่าจะไม่นอกใจ
ทัณฑ์บน

description: วารสารนิติศาสตร์ มหาวิทยาลัยแม่ฟ้าหลวง, 7, 2, 409-428
title: U-Net Model for the Identification and Segmentation of the Endocardium in cMR Imaging
Creators: name: Sulaiman, Hajir
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: Cardiac
subject: MR physics
subject: MR
subject: Physics
subject: Segmentation
subject: Image verification

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Purpose- To assess the performance of the U-Net Model for the detection and segmentation of the inner endocardial wall of the left ventricle for the calculation of the left ventricular ejection fraction (LVEF) from Cardiac Magnetic Resonance...
Multi-ethnicity of literary culture in courtly circles of 12th century England
Creators: name: Smoczyk-Jackowiak, Idalia
Publisher: name: Polilog. Studia Neofilologiczne
Year: 2016

description: Multi-ethnicity of literary culture in courtly circles of 12th century England The purpose of this paper is to illustrate the ambivalent attitude of writers attached to the Angevin court towards multi-ethnicity of that milieu. Both, biographies and writings of those courtier-clerics show the subversive nature of the blend of national identities. William of Malmesbury, who was of Anglo-Norman parentage, used a disquieting literary image of a deformed female body, symbolizing imminent collapse of the cross-channel realm. Geoffrey of Monmouth, Walter Map and Gerald of Wales, all of Welsh-Norman descent, expressed their anxiety through disturbing images of conflicting races, infernal regions producing chaos and epistemological uncertainty, or through a richly metaphoric journey image. Finally, despite internally experienced tensions, all writers embraced their native oral traditions. Geoffrey of Monmouth appropriated Arthurian legends into the clerical literary discourse. Walter Map used elements of Celtic folklore, including fairy beliefs, to provide cultural continuity with the past culture. Finally, Gerald of Wales expressed his ambivalent attitude towards complex Welsh-English relations by assimilating the supernatural into the historical. As a result, those authors managed to encompass in their writings at least two separate literary traditions: on the one hand, Latin literary culture, on the other, oral vernacular folklore. Thus, unwritten, vernacular myths gradually penetrated into the official written culture.
description: Polilog. Studia Neofilologiczne, No. 6 (2016): Polylogue. Neophilological Studies
„Krasnoludki są na świecie” (i w przekładzie). O angielskim tłumaczeniu O krasnoludkach i o sierotce Marysi Marii Konopnickiej
Creators: name: Budrewicz, Aleksandra
Publisher: name: Polilog. Studia Neofilologiczne
Year: 2016

description: “There are dwarfs in this world” (and in translation). On an English translation of Maria Konopnicka’s The Brownie Scouts The article is devoted to an English translation of a famous and well-known Polish story O krasnoludkach i o sierotce Marysi by Maria Konopnicka (1895). The translation was published in 1929 by an English writer Kate Żuk-Skarszewska; its title, The Brownie Scouts, emphasizes the story of the dwarfs rather than the parallel between the history of the dwarfs intertwined with that of a little orphan girl Marysia. The article offers a comparative analysis of the source text and the English translation. Theoretical aspects of children literature in translation are shortly discussed. A special attention was given to Żuk-Skarszewska’s modifications, among which reductions and amplifications are often used.
description: Polilog. Studia Neofilologiczne, No. 6 (2016): Polylogue. Neophilological Studies
Rotating black holes in Einstein-Dilaton-Gauss-Bonnet gravity with finite coupling
Creators: name: Maselli, Andrea
name: Pani, Paolo
name: Gualtieri, Leonardo
name: Ferrari, Valeria
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Among various strong-curvature extensions to General Relativity, Einstein-Dilaton-Gauss-Bonnet gravity stands out as the only nontrivial theory containing quadratic curvature corrections while being free from the Ostrogradsky instability to any order in the coupling parameter. We derive an approximate stationary and axisymmetric black-hole solution of this gravitational theory in closed form, which is quadratic in the black-hole spin angular momentum and of seventh order in the coupling parameter of the theory. This extends previous work that obtained the corrections to the metric only at the leading order in the coupling parameter, and allows us to consider values of the coupling parameter close to the maximum permitted by theoretical constraints. We compute some geometrical properties of this solution, such as the dilaton charge, the moment of inertia and the quadrupole moment, and its geodesic structure, including the innermost-stable circular orbit and the epicyclic frequencies for massive particles. The latter represent a valuable tool to test General Relativity against strong-curvature corrections through observations of the electromagnetic spectrum of accreting black holes.
description: Minor bug fixed in the supplementary mathematica notebook
title: Children pilocytic astrocytoma: imaging options and differential diagnosis features.
Creators: name: Plakhotina, Nadezhda
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: CNS
subject: Oncology
subject: Paediatric
subject: MR
subject: Technical aspects
subject: Metastases

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: Our purpose was to determine MR patterns and unique signs of different variants of the pilocytic astrocytoma in...
Conical refraction healing after partially blocking the input beam
Creators: name: Turpin, Alex
name: Loiko, Yury V.
name: Kalkandjiev, Todor K.
name: Corbalán, Ramón
name: Mompart, Jordi
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In conical refraction, when a focused Gaussian beam passes along one of the optic axes of a biaxial crystal it is transformed into a pair of concentric bright rings at the focal plane. We demonstrate both theoretically and experimentally that this transformation is hardly affected by partially blocking the Gaussian input beam with an obstacle. We analyze the influence of the size of the obstruction both on the transverse intensity pattern of the beam and on its state of polarization, which is shown to be very robust.
Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
Creators: name: Becker-Dreps, Sylvia
name: Schmulson, Max
name: Cáceres, Mercedes
name: Cortes, Loreto
name: Morgan, Douglas R.
name: Peña, Rodolfo
name: Martin, Christopher F.
name: Benshoff, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the “nonsterile” developing world environment. IBS subjects were identified from a population-based sample of 1624 participants using the Rome II Modular Questionnaire. Stool samples from cases and randomly selected controls were examined for ova and parasites. Logistic regression models explored the relationship between IBS and parasite infection. The overall IBS prevalence among participants was 13.2% (9.3% males, 15.9% females). There was no difference in parasite carriage between IBS cases and controls, 16.6% versus 15.4% (), nor among IBS subtypes. The pathophysiology of post-infectious IBS may be altered in the developing world as compared to industrialized nations and warrants investigation.
title: Updates in the clinical application of Magnetic Resonance Fingerprinting and it’s future
Creators: name: Mohey, Nesreen
Publisher: name: European Congress of Radiology
Year: 2022
Subjects: subject: Artificial Intelligence
subject: MR
subject: Imaging sequences
subject: Artifacts

description: Purpose Methods and materials Results Conclusion Personal information and conflict of interest References
description: Purpose: The aim was to increase the awareness of the radiologists about Magnetic Resonance Fingerprinting, this new technique and its applications, which could be implemented in the near...