cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
High precision, good recovery and fast determination of alfa-tocopherol (Vitamin E) in serum and plasma samples? This is your analytical method
Creators: name: Rodríguez Robledo, Virginia
name: Villaseca, Noemí
name: Castro Vazquez, Lucía
name: Lozano, Mª Victoria
name: Santander, Manuel
name: Gonzalez Fuentes, Joaquín
name: Marcos, Mª Pilar
name: Arroyo, Mª Mar
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Vitamin E comprises a family of four tocopherols and four tocotrienols (α, β-, γ- and δ-), all of them antioxidants compounds. α-Tocopherol (α-T) showed superior biological activity [1] over the other compounds and is the major tocopherol present in blood and tissues [2]. Being antioxidant α-T reduce oxidative stress (OS) and could be implicated in the etiopathology of a number of diseases as reducing the risk of cancer, cardiovascular and neurodegenerative diseases [3].
 This experimental work have been focused to develop a high quality, specific and fast analytical methodology for determination of α-T in biological samples using LC-ESI-MS. For that, chromatographic (mobile phase composition and flow, temperature and column C-18 2.1 x 50 mm-1.8 μm), electrospray ionization (negative) and mass spectrometric parameters (quali and quanti transitions, gas flow and temperature, nebulizer) have been carefully optimized. In addition, validation procedure (precision, recoveries, limits of quantitation, linearity…) have been carried out using a deutered compound of α-T (d6-α-T) in order to obtain a reproducible, sensible and accuracy analytical method. The optimized and validated analytical method has been applied for determination of concentration of α-T in serum and plasma samples. The pretreatment of biological samples from total blood have been also optimized.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Ji shenzhou sanbao gantong lu 集神州三寶感通 錄 also known as “Sanbao gantong lu 三寶感通錄”, “Record of Miracles”, “Dongxia sanbao gantong ji 東夏三寶感通記”, “Dongxia sanbao gantong lu 東夏三寶感通錄”
Creators: name: Landry, Nelson
Publisher: name: Database of Religious History (DRH)
Year: 2022

description: The Ji shenzhou sanbao gantong lu 集神州三寶感通錄 is a collection of miracle tales completed in 664 by the Tang dynasty scholar monk Daoxuan 道宣 (596-667). Miracle tales record the accounts of monks, lay believers, patrons, of sacred places as well as religious objects, structures, and scriptures. These stories are didactic by nature, teaching of the supremacy of the Buddhist faith by recounting miraculous events related to acts of spreading the Teaching (hongfa 弘法) and defending Buddhism in the face of adversity (hufa 護法). After gathering sources for decades out in the field and in the libraries of the Ximing Monastery 西明寺, Chang’an, Daoxuan completed this text at the secluded Jingye Monastery 靜業寺 in the Zhongnan mountains near the capital. Daoxuan and Daoshi 道世 (d. 683) collaborated at Ximing, and many of the accounts that appear in the Record of Miracles, also appear in Daoshi’s great Buddhist encyclopedia, the Fayuan zhulin 法苑珠林 (A Forest of Pearls from the Dharma Garden). A quick glance at the sources used in the Record of Miracles reveals that the two primary outside sources used were the Mingxiang ji 冥祥記 (Records of Signs From the Unseen Realm; c.490) by Wang Yan 王琰 and the Gaoseng zhuan 高僧傳 (Biographies of Eminent Monks; c.530) by Huijiao 慧皎—two foundational texts in the biography and miracle tale tradition. Additionally, Daoxuan was an assiduous recorder of Buddhist history who did not fail to read official sources, especially the court histories such as the Wei shu 魏書 (History of the Wei), the Liang shu 梁書 (History of the Liang), and the Zhou shu 周書 (History of the [Northern] Zhou). He also took from sources concerned with local history, often referring to geographical works, gazetteers as well as local records. The Record of Miracles is divided into five thematic sections distributed over three fascicles. These sections are (1) the miracles relating to Buddhist relics (Skt. śarīra) and the pagodas that mark their location (sheli biaota 舍利表塔) in the first fascicle; (2) the miracles relating to the discovery of numinous Buddhist images (lingxiang chuilong 靈像垂降) in the second fascicle; (3) finally, the miracles relating to holy monasteries (shengsi 聖寺), (4) numinous teachings (lingjiao 靈教), (5) and extraordinary monks (shenseng 神僧) in the third fascicle. The overarching themes of this text revolve around the tripartite classification of Buddhist religious life into different “Jewels” (Skt. triratna; Ch. sanbao 三寶), with separate sections of the text corresponding to separate aspects of the Three Jewels. Following this thematic schema, (1) the sections on relics, pagodas and images correspond to the buddhas; (2) the section on auspicious scriptures corresponds to the teachings; (3) the sections on holy monasteries and extraordinary monks correspond to the monastic community.
Martarega williamsi Truxal 1949
Creators: name: Peralta-Argomeda, Jorge Luis
name: Rodrigues, Juliana Mourão Dos Santos
name: Huamantinco-Araujo, Ana
name: Moreira, Felipe Ferraz Figueiredo
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Notonectidae
Martarega
Martarega williamsi

description: Martarega williamsi Truxal, 1949
 Geographic distribution. Panama, Brazil, Ecuador, Peru (Truxal 1949).
 Distribution in Peru. Ucayali, Huánuco, Junín (Truxal 1949).
description: Published as part of Peralta-Argomeda, Jorge Luis, Rodrigues, Juliana Mourão Dos Santos, Huamantinco-Araujo, Ana & Moreira, Felipe Ferraz Figueiredo, 2024, Checklist of the aquatic and semiaquatic bugs (Hemiptera: Heteroptera: Gerromorpha, Leptopodomorpha & Nepomorpha) of Peru, pp. 1-72 in Zootaxa 5467 (1) on page 41, DOI: 10.11646/zootaxa.5467.1.1, http://zenodo.org/record/11613746
Camphorquinone-induced oxidative stress and mutations in L5178Y TK+/- mouse lymphoma cells
Creators: name: Volk, Joachim
name: Leyhausen, Gabriele
name: Geurtsen, Werner
name: Ziemann, Christina
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Camphorquinone (CQ) is the most important photo-initiator used in dental composite resins. Aim of this study was to evaluate its genotoxic and mutagenic potential in L5178Y TK+/- mouse lymphoma cells. Genotoxicity was assessed by alkaline comet assay and mutagenic potential by mouse lymphoma assay (MLA). The fluorescent dye dichlorofluoresceine diacetate (DCFH-DA) and the 8-hydroxyguanine DNA-glycosylase 1 (hOGG1)-modified comet assay were used to measure CQ´s oxidative potential and its impact on DNA. In this study, CQ (0.5-2.5mM) induced a concentration- and time-dependent inhibition in cell growth with a concomitant increase in intracellular generation of reactive oxygen species (ROS) (2.5mM: 2342%±1108%, control: 74%±4%). In addition, CQ significantly caused DNA-strand breaks at 2.5mM, shown by elevated tail moment (5-fold), and generated oxidative lesions in the form of 8-hydroxy-2'-deoxyguanosines within the cellular genome at 1.25mM–2.5mM. In MLA, CQ produced a slight, concentration-dependent mutagenic response, however, at concentrations already mediating reduction in relative total growth of ≥50%. Metabolic activation by S9 mix had no impact. We conclude that CQ possesses genotoxic and weak mutagenic potential in L5178Y TK+/- cells, most likely via ROS generation. However, at least for the investigated parameters, the pronounced cytotoxicity exhibited by CQ may outweigh any mutagenic potential.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
title: Βελτιστοποίηση της αξιοπιστίας του σχεδιασμού φωτοβολταϊκών συστημάτων που ενσωματώνονται σε κτήρια
title: Optimization of design reliability of building- integrated photovoltaic systems
Creators: name: Τριανταφυλλου Ιωαννης
Publisher: name: Technical University of Crete
Year: 2022

description: Η χρήση των Ανανεώσιμων Πηγών Ενέργειας (Α.Π.Ε.) γίνεται όλο και πιο διαδεδομένη στη σημερινή εποχή και ειδικότερα η τεχνολογία των φωτοβολταϊκών συστημάτων, τα οποία έχουν την δυνατότητα να ενσωματωθούν σε κατοικίες και κτήρια ως δομικά στοιχεία της κατασκευής τους. Τα φωτοβολταϊκά συστήματα μπορούν να παράγουν ηλεκτρική ενέργεια για την κάλυψη του απαιτούμενου φορτίου, έχουν όμως το μειονέκτημα ότι η αξιοπιστία λειτουργίας τους επηρεάζεται από τις χρονικά μεταβαλλόμενες καιρικές συνθήκες που επικρατούν στην περιοχή εγκατάστασης τους.
Σε αυτή την διπλωματική εργασία αναπτύχθηκε μία υπολογιστική μέθοδος σχεδιασμού φωτοβολταϊκών συστημάτων που ενσωματώνονται σε κτήρια, με στόχο την βελτιστοποίηση της αξιοπιστίας τους. Η βελτιστοποίηση πραγματοποιείται για φωτοβολταϊκά συστήματα που είναι διασυνδεδεμένα με το ηλεκτρικό δίκτυο και έχουν τη δυνατότητα αποθήκευσης ενέργειας, για συστήματα που είναι διασυνδεδεμένα με το ηλεκτρικό δίκτυο και δεν έχουν την δυνατότητα αποθήκευσης ενέργειας και για συστήματα που είναι πλήρως αυτόνομα. Η διαδικασία βέλτιστου σχεδιασμού κάθε φωτοβολταϊκού συστήματος πραγματοποιείται με προσομοίωση της λειτουργίας του χρησιμοποιώντας πολλαπλές χρονοσειρές ηλιακής ακτινοβολίας και θερμοκρασίας περιβάλλοντος κατά τη διάρκεια ολόκληρου του χρόνου ζωής του, οι οποίες παράγονται από κατάλληλα εκπαιδευμένο Stochastic Weather Generator. Τα αποτελέσματα βελτιστοποίησης έδειξαν ότι με την μέθοδο σχεδιασμού που αναπτύχθηκε, βελτιώνεται η αξιοπιστία των φωτοβολταϊκών συστημάτων σε σύγκριση με τη σχεδίαση τους χρησιμοποιώντας μετεωρολογικά δεδομένα που βασίζονται μόνο στο Typical Meteorological Year.
Experiment data for the paper "Connection-minimal Abduction in EL via translation to FOL"
Creators: name: Haifani, Fajar
name: Koopmann, Patrick
name: Tourret, Sophie
name: Weidenbach, Christoph
Publisher: name: Zenodo
Year: 2022
Subjects: Description Logics
Abduction
Reasoning

description: Data and implementation used in the experiments in the paper "Connection-minimal Abduction in EL via translation to FOL" accepted at IJCAR 2022. See readme-file in the archive on how to rerun the experiments.

 If you are just interested in the abduction tool, but do not wish to repeat the experiments, we recomment to go to the website of CAPI.
Ptolemaic Egypt : Egyptian Religion
Creators: name: Pfeiffer, Stefan
Publisher: name: Database of Religious History (DRH)
Year: 2022

description: This entry consists of data that refers to what we today call Egyptian religion, dating to the "Ptolemaic Period". It is a stage of the Egyptian cults that immediately followed the previous epochs and used the conventional Egyptian motifs, practices and texts in its forms of expression. Egyptian religion was not ethnically bound, but exerted a great attraction also on the immigrants in Egypt. In principle, it was open to everyone to participate in the local cults.
Positive effects of resistance exercise training on cachexia-associated muscle waste, inflammation and oxidative stress in walker-256 tumor-bearing rats.
Creators: name: Padilha, Camila S.
name: Borges, Fernando H.
name: Silva, Lilian E.C.M
name: Frajacomo, Fernando T.T
name: Jordão, Alceu A
name: Duarte, José Alberto
name: Cecchini, Rubens
name: Guarnier, Flávia A
name: Deminice, Rafael
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The main of our study was to investigate the effects of resistance exercise training (RE) on prevention of muscle waste, oxidative stress (OS) and inflammation in Walker-256 tumor-bearing rats. Thirty-seven Wistar rats were divided into 4 groups: control group (C,n=9), tumor-bearing (T,n=10), exercised group (E,n=9) and tumor-bearing exercised (TE,n=10). RE protocol consisted of climbing a ladder apparatus with weights tied to the animal's tail. After 6 weeks of RE training, Walker-256 tumor cells were implanted in the right flank. Animals of E and TE continued the RE training for more 12-days.  Results showed muscle wasting T group (P75 3.535μm2), body weight loss (-12.2±7.8g), increased systemic leukocytes (20.8±3.4cummx103) and inflammatory interleukins TNF-α (T:8.1±2pg/ml) as well, MDA (T:151.6±13.8 µmol/g protein), lipid hydroperoxide (T:646.1±29.8µmol/g protein) and GSH/GSSG (T:2.1±0.4). In contrast, RE in TE group was able to mitigate body weight loss (3.2±2.3g) and muscle wasting (P75 5.571μm2) with the attenuation of muscle OS MDA (TE:75.25±9.1µmol/g protein), lipid hydroperoxide (TE:305.7±68.6µmol/g protein), GSH/GSSG (TE:3.8±0.3) and systemic inflammatory markers TNF-α (TE:4.4±1.8pg/ml) and increased ant-inflammatory IL-10 (TE:498.9±205.5pg/ml). In conclusion, implantation of Walker-256 tumor promotes weight loss, muscle atrophy and reduced muscle strength. However, RE maintained muscle strength in TE animals and decreased OS and inflammation.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Nanotechnology approaches to minimize oxidative stress damage in sperm samples
Creators: name: Fernández-Santos, María Rocío
name: Sánchez-Rubio, Francisca
name: Rodriguez-Robledo, Virginia
name: Plaza-Oliver, Maria
name: Santander-Ortega, Manuel Jesús
name: García-Álvarez, Olga
name: Maroto-Morales, Alejandro
name: Soler, Ana Josefa
name: Lozano, Maria Victoria
name: Arroyo-Jimenez, María Del Mar
name: Garde, José Julian
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Vitamin E is known as a potent antioxidant, however high concentrations may act as an oxidation stimulator, especially affecting sperm motility. The protective ability of vitamin E nanoemulsions (NE) [1] was tested on ovine thawed spermatozoa. Thawed sperm samples (3 rams) were pooled and incubated with 0 (Control), NE without vitamin E (NNE), 2, 4 and 6 mM of vitamin E included in nanoemulsions. Sperm motility (MI), viability (YO-PRO-1/IP), acrosome status (PNA/PI) and lipoperoxidation (C11-BODIPY 581/591) were evaluated after thawing and after 2 h of incubation (37ºC). Data were analyzed by GLM-ANOVA procedures (3 replicates). After 2h of incubation, sperm motility did not decrease with increasing concentrations of vitamin E [43.3 (Control), 45.0 (NNE), 51.6 (2 mM), 51.6 (4 mM) and 53.3 (6 mM)] (P>0.05) but also we observed an improving trend. Moreover, high concentration (6 mM) significantly increased the percentage of viable sperm without lipoperoxidation after 2 h of incubation [21.5 (Control), 25.3 (NNE), 28.9 (2 mM), 29.6 (4 mM) and 34.8 (6 mM)] (P=0.019). Our work showed an innovation for enhancing the antioxidant potential of vitamin E on sperm quality avoiding lipoperoxidation and maintaning sperm motility. Our work presents nanotechnology as a new research tool in spermatology.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Notonecta inca Mazzucconi 2000
Creators: name: Peralta-Argomeda, Jorge Luis
name: Rodrigues, Juliana Mourão Dos Santos
name: Huamantinco-Araujo, Ana
name: Moreira, Felipe Ferraz Figueiredo
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Notonectidae
Notonecta
Notonecta inca

description: Notonecta inca Mazzucconi, 2000
 Geographic distribution. Peru (Mazzucconi 2000).
 Distribution in Peru. Junín (Mazzucconi 2000).
description: Published as part of Peralta-Argomeda, Jorge Luis, Rodrigues, Juliana Mourão Dos Santos, Huamantinco-Araujo, Ana & Moreira, Felipe Ferraz Figueiredo, 2024, Checklist of the aquatic and semiaquatic bugs (Hemiptera: Heteroptera: Gerromorpha, Leptopodomorpha & Nepomorpha) of Peru, pp. 1-72 in Zootaxa 5467 (1) on page 41, DOI: 10.11646/zootaxa.5467.1.1, http://zenodo.org/record/11613746
DIFFERENTIATED AND PROLIFERATING HUMAN INTESTINAL CELL LINE CACO2: DIFFERENCE IN ACTIVITY OF ANTIOXIDANT ENZYMES AND THEIR MODULATION BY SELECTED SESQUITERPENES
Creators: name: Bártíková, Hana
name: Lněničková, Kateřina
name: Hanušová, Veronika
name: Matoušková, Petra
name: Skálová, Lenka
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The Caco2 cell line serves as model of colorectal cancer. Moreover, these cells can undergo spontaneous differentiation leading to formation of cells with characteristics of mature enterocytes. Thus, Caco2 cell line can be used either as cancer model or intestinal barrier (proliferating vs. differentiated cells).
 Our study tested the differences in activity of antioxidant enzymes between proliferating and differentiated Caco2 cells. Additionally, we studied the effect of potential anticancer agents - sesquiterpenes on these enzymes in both cell types. Proliferating and differentiated cells were incubated with Myrica rubra essential oil and its 2 substantial sesquiterpene components a-humulene and trans-nerolidol (25 µg/ml) for 48 hours.
 Glutathione peroxidase, glutathione reductase and catalase activities were lower in proliferating (cancerous) cells than in differentiated (normal) ones. From sesquiterpenes, trans-nerolidol was the only enzymatic modulator. It increased glutathione S-transferase activity in proliferating and differentiated Caco2, while superoxide dismutase activity only in proliferating cells in comparison to corresponding controls.
 Diminished antioxidant enzymes activity in proliferating cells causes higher vulnerability of cancerous cells to oxidative stress. As sesquiterpenes have not decreased antioxidant enzymes activity, another anticancer mechanism can be expected, e. g. reactive oxygen species production.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
EFFECT OF OBESITY IN THROMBOXANE A2 SYNTHESIS IN CORONARY CIRCULATION
Creators: name: López, Selma
name: Ríos, Amelia
name: Escalante, Bruno
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Obesity leads to chronic oxidative stress altering vascular homeostasis and promoting development of cardiovascular diseases.  Endothelium metabolism is directly affected by oxidative stress.
We investigated the role of oxidative stress on coronary vascular response mediated by TXA2 during obesity.
Mice (C57BL/6) were fed with standard chow or a high fat diet for 8 weeks. To evaluate the role of RNS peroxynitrite during obesity, mice were treated with a peroxynitrite decomposition catalyst FETMPyP (25 mg/kg/day) for 20 days.  Langendorff isolated perfused heart system was used to evaluate vascular response to acetylcholine in coronary arteries and to obtain perfusates. Thromboxane B2 (TXB2) was quantified in perfusates by ELISA. Thromboxane synthase (TXS) expression was measured by western blot.
An enhanced contractile response to acetylcholine was observed in obese group compared with control group; this was associated with an elevated expression of TXS and increased TXA2 synthesis. FETMPyP treatment prevented the enhanced contractile response to Ach, and the altered expression of TXS and synthesis of TXB2 observed in obese mice.

We suggest that peroxynitrite promotes coronary vasoconstriction through cyclooxygenase pathway vasoconstrictor metabolites in obese mice.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
RES4CITY Case Study: Gender inclusion in work processes with renewable energy projects in cities (Full version)
Creators: name: WiTEC
Publisher: name: Zenodo
Year: 2024
Subjects: gender inclusion
organisational change
change management
inclusivity initiatives
employee participation
case study

description: This study analyses two organizational change initiatives, one successful and one unsuccessful, to understand the factors influencing resistance and success in gender inclusion. The purpose is to identify key elements for increasing the likelihood of success in similar projects. Success factors include internal initiation, voluntary participation, theory-practice integration, expertise, adequate time for research and change, bridging status gaps, forming alliances, adopting an evolutionary approach, addressing resistance, and emphasizing fairness and justice.
title: El Mejdub
Creators: name: Gutova, Evgeniya
Publisher: name: Pangloss
Year: 2022
Subjects: subject: Linguistique
subject: Senhaja de Srair (Zerqet)

description: This story builds on the local legend that Abderrahman Lmejdub (El Majdoub) left the Senhaja people communicating with a mixed (or mixed-up) language. The story explains why this language is mixed with pieces of many languages.
Examining Mn-Peptide Complexes Applied to the Preparation of Irradiated Vaccines
Creators: name: K. Gaidamakova, Elena
name: Grichenko, Olga
name: Matrosova, Vera
name: Sharma, Ajay
name: Marts, Amy
name: Hoffman, Brian
name: Daly, Michael
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Antioxidant Mn-peptide complexes accumulated in the extremely radiation-resistant bacterium Deinococcus radiodurans have a remarkable ability - they protect the structure and functions of proteins exposed to massive doses of ionizing radiation, but they do not significantly protect nucleic acids. We designed a decapeptide DEHGTAVMLK (DP1) whose amino acid composition was selected to include most of the prevalent amino acids in the protective fraction of D. radiodurans cell extracts. DP1 spontaneously forms antioxidant complexes with Mn2+ and orthophosphate (MDP) which uncouple protein damage from DNA/RNA damage during supralethal exposures to gamma-radiation. This approach has been applied to the preparation of irradiated vaccines. An ideal whole-organism vaccine lacks any infectivity, but retains all original epitopes needed to mount a protective immune response. Indeed, MDP preserves antigenic structures in aqueous preparations of lethally-irradiated viruses and bacteria. The structure/function relationships of DP1 were interrogated by LC/MS and HPLC. Upon exposure to gamma-rays, the radiation-dependent decay of DP1 correlates to the loss of protective ability of proteins. Interaction between DP1 and Mn was examined in aqueous solution by nuclear magnetic resonance and electron nuclear double resonance spectroscopy. Several amino acids in DP1 are more important for MDP complex formation than others.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Partizipative Forschung zur Nitratbelastung: Ergebnisse des Nitrat-Monitorings (Themenheft 3)
Creators: name: Brockhage, Frauke
name: Lüsse, Mientje
name: Pietzner, Verena
name: Beeken, Marco
Publisher: name: Universität Osnabrück
Year: 2022
Subjects: subject: Citizen Science
subject: Stickstoff
subject: Gewässerschutz
subject: Nachhaltigkeit
subject: 500 - Naturwissenschaften
subject: 540 - Chemie
subject: 550 - Geowissenschaften
subject: 570 - Biowissenschaften, Biologie
subject: 30.00 - Naturwissenschaften allgemein: Allgemeines
subject: 38.00 - Geowissenschaften: Allgemeines
subject: 43.00 - Umweltforschung, Umweltschutz: Allgemeines
subject: 35.00 - Chemie: Allgemeines
subject: 42.00 - Biologie: Allgemeines

description: Die Stickstoffbelastung der Umwelt nimmt in der gesellschaftlichen Diskussion einen immer größer werdenden Stellenwert ein. Gleichzeitig wächst in der Gesellschaft das Interesse, an aktuellen Forschungsthemen teilzuhaben. Daher wurde von den Universitäten Oldenburg und Osnabrück ein Citizen Science-Projekt zur Stickstoffbelastung ins Leben gerufen und von der Deutschen Bundesstiftung Umwelt (DBU) gefördert. In diesem dritten Themenheft werden die Ergebnisse des Nitrat-Monitorings dargestellt.
Advancing Battery Safety: Unveiling Thermal Runaway with a Custom Test Bench
Creators: name: Brahmbhatt, Keval
name: Kevlishvili, Nina
name: Kraft, Jonas
name: :Unav
Publisher: name: Fraunhofer-Gesellschaft
Year: 2022

description: Thermal runaway poses a critical challenge in the safe operation of lithium-ion batteries. This study is focusing on TR (Thermal Runaway) experiments conducted within a unique spherical test bench, aiming to explore and compare the thermal behaviors of LFP (Lithium Iron Phosphate) and NMC (Nickel Manganese Cobalt Oxide) cells. The investigation seeks to scrutinize existing notions that LFP cells inherently manifest enhanced safety compared to NMC cells, while also shedding light on the diverse thermal behaviors exhibited by these two most common battery chemistries.
Ochterus bidentatus Schell 1943
Creators: name: Peralta-Argomeda, Jorge Luis
name: Rodrigues, Juliana Mourão Dos Santos
name: Huamantinco-Araujo, Ana
name: Moreira, Felipe Ferraz Figueiredo
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Ochteridae
Ochterus
Ochterus bidentatus

description: Ochterus bidentatus Schell, 1943
 Geographic distribution. Peru (Schell 1943).
 Distribution in Peru. Huánuco (Nieser & Chen 1992), Junín (Schell 1943; Nieser & Chen 1992), Ayacucho (Schell 1943).
description: Published as part of Peralta-Argomeda, Jorge Luis, Rodrigues, Juliana Mourão Dos Santos, Huamantinco-Araujo, Ana & Moreira, Felipe Ferraz Figueiredo, 2024, Checklist of the aquatic and semiaquatic bugs (Hemiptera: Heteroptera: Gerromorpha, Leptopodomorpha & Nepomorpha) of Peru, pp. 1-72 in Zootaxa 5467 (1) on page 41, DOI: 10.11646/zootaxa.5467.1.1, http://zenodo.org/record/11613746
Do glycation end products in infant formula contribute to long term oxidative stress?
Creators: name: Abdennebi-Najar, Latifa
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objective: the aim of this study is to determine the involvement of formulas AGEs in the programming process of oxidative stress during infancy. Results: Evidences in rodent and baby pig1 highlighted the involvement of formula AGEs-RAGE dependent mechanisms in long term oxidative stress and inflammation in pancreas, kidney2, liver and colon3 denoting that these organs are the major targets of AGEs. Conclusion: A high load of IF AGEs during postnatal life can presume of a programming process modulating the activity and function of several organs and leading to the development of adult diseases as diabetes and kidney failure. The potential involvement of infant formula melanoidines on microbiota and long term antioxidant defense is largely unknown but merit to be studied.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Oxidative stress and plaque psoriasis
Creators: name: COSTANTINO, MARIA
name: CONTI, VALERIA
name: MARONGIU, MARIAGRAZIA BATHILDE
name: FILIPPELLI, AMELIA
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The literature demonstrated the involvement of oxidative stress in pathogenesis of the plaque psoriasis, a chronic inflammatory skin disease with negative impact on the quality of life and with differences of gender. The available therapeutic strategies for plaque psoriasis include spa (salus per aquam) therapy by using sulphurous mineral waters that researches have demonstrated associated to antioxidant effect. Thus we investigated on 58 psoriatic subjects (34 women=group A and 24 men=group B) admitted to sulphurous spa treatments for 2 weeks in Italian spas (as Telese Bath - Benevento, Italy) gender differences in pruritus (VAS-score), PASI index, impact on quality of life (DLQI) and plasma concentration of ROMs (by d-ROMs Test, Diacron-Grosseto-Italy) before treatments initiation and in the spa treatments prescribed. The results showed that the sulphurous spa therapy induced versus baseline in both groups A and B examined: a significant (p<0.05) reduction of clinical parameters (itching and PASI-score) observed; improvement of the quality of life and reduction in the [ROM] plasma. The spa sulphurous treatments has a greater effect in women. In conclusion our data suggests that sulphurous spa therapy could represent an important component of the overall strategy to treatment plaque psoriasis.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
The effects of Metformin on mitochondrial function in granulosa-cumulus cells
Creators: name: Lavut, Anna
name: Kim, Kyunga
name: Bentov, Yaakov Haim
name: Jurisicova, Andrea
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Metformin, is the most widely used treatment for type II diabetes. Recently it has been broadly adopted for the treatment of PCOS prior and during pregnancy. Despite decades of clinical use, it was only recently shown that most of the actions of metformin are mediated via inhibition of the first complex of the mitochondrial electron transport chain and ATP production. Oocytes and early embryos are totally dependent on mitochondrial ATP and are extremely sensitive to disturbances in mitochondrial function. Aim: To compare mitochondrial function in murine oocytes and granulosa/cumulus (GC) cells that support oocyte metabolism. Young nonobese female ICR females were treated 5x a week for 16 days with 300mg/kg of metformin. After 16 days females were superovulated and oocytes used for various mitochondrial assays. Metformin treatment did not increase ovulation rates or changed cumulus cell number/oocyte. However, significantly more mitochondria, decreased mitochondrial ROS production and oxidized FAD levels were detected in oocytes exposed to Metformin. When GC were cultured with Metformin, a 25% decline in cellular ATP concentration was observed. These results suggest that Metformin exerts cell specific effects and further studies are needed to guarantee its safe use.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
DECADES IN REVIEW: A BIBLIOMETRIC ANALYSIS OF GLOBAL AND CHINESE RESEARCH ON COLLEGE ENGLISH TEACHING (2003-2022)
Creators: name: Ming, Zhang Wei
Publisher: name: Zap journal
Year: 2024
Subjects: Blended teaching
Flipped classroom
Higher education
Autonomous learning
Teaching reforms

description: College English courses are foundational for nearly all college students in China. The landscape of College English teaching in China has undergone iterative reforms, leading to a persistent debate between academic English and general English. While these reforms have generally enhanced university English teaching, there has been a tendency to overemphasize model constructs in college English teaching research.

In response to the evolving integration of college English cultural teaching models and modern information technology, several scholars have endeavored to create intelligent systems that extend the reach and depth of modern information technology in college English cultural education. These initiatives unlock the vast potential of modern information technology, paving the way for innovative directions in college English cultural teaching.

This paper draws upon the work of Zhang and others who have identified effective methods for teaching English using mobile devices. By synthesizing these advancements, the paper contributes to the ongoing discourse surrounding the optimal blend of technology and pedagogy in college English teaching, while maintaining scientific and efficient approaches.
Effects of marginal dietary vitamin B3 levels on metabolic flexibility and anti-oxidant response in mice exposed to a high fat diet.
Creators: name: Hegeman, Maria
name: Shi, Wenbiao
name: Tang, Jing
name: Van Dartel, Dorien
name: Swarts, Hans
name: Keijer, Jaap
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objective: Nicotinamide adenine dinucleotide (NAD+) preserves cellular redox state and basal energy metabolism. Maintenance of NAD+ levels is dependent on dietary vitamin B3 levels, which is a NAD+ precursor. Although it is evident that severe vitamin B3 deficiency causes disease, little is known on the physiological consequences of marginal vitamin B3 levels. Therefore, the effects of marginal dietary vitamin B3 levels on metabolic flexibility and anti-oxidant response were studied.
Methods: Adult male mice were exposed to a HFD containing 5 or 30 mg nicotinamide riboside (NR) per kg diet. Body weight, lean mass, fat mass and feed intake were measured weekly. After 14 weeks, metabolic flexibility was assessed with a fasting and refeeding challenge using indirect calorimetry. After 15 weeks, the anti-oxidant response was determined in epididymal white adipose tissue.
Results: Whole body physiological parameters were not affected by dietary NR. Upon a fasting and refeeding challenge, the delta respiratory exchange ratio (ΔRER) was higher when comparing 30 to 5 mg/kg NR. Expression levels of anti-oxidant genes were enhanced in the 30 mg/kg group compared to the 5 mg/kg group.
Conclusion: Current results suggest that 30 mg/kg NR increases metabolic flexibility and anti-oxidant levels compared to 5 mg/kg NR.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Human alpha-Thrombin Binds to and Potently Inhibits Leukocyte Myeloperoxidase: A Novel Biochemical Link Between Inflammation and Coagulation
Creators: name: Acquasaliente, Laura
name: Fasoli, Sabrina
name: Sokolov, Alexej
name: Kostevich, Valeria
name: Vasilyev, Vadim
name: De Filippis, Vincenzo
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Human alpha-Thrombin (aT) is a serine protease that plays a pivotal role at the interface between inflammation and coagulation. aT displays both pro-coagulant (i.e., fibrin generation and platelets activation) and anti-coagulant (generation of the anticoagulant Protein C) functions in haemostasis. We have recently discovered that aT displays pro-inflammatory functions by proteolytically degrading ceruloplasmin (CP), an acute phase protein acting as a potent inhibitor of leukocyte myeloperoxidase (MPO), a key enzyme boosting ROS production in the front-line defense against bacteria in innate immunity. Notably, aT-proteolyzed CP has lost the ability to inhibit MPO [1].
 Using several different biochemical/biophysical techniques, in this work we demonstrate that aT binds to MPO with high affinity (Kd=10-30nM) and, more importantly, potently inhibits MPO peroxidise activity on the ABTS(2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) substrate, with an apparent inhibition constant KI=50nM. Interestingly, MPO does not influence the amidolytic activity of aT. These findings highlight the possibility that, similarly to what observed in the haemostasis, aT plays two opposite roles in inflammation: a pro-inflammatory role, related to the proteolytic inactivation of CP, and an anti-inflammatory role, which unfolds via direct inhibition of MPO.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Supplementary document for Multiband tunable exciton-induced transparencies: Exploiting both strong and intermediate coupling in a nanocube-hexagonal-nanoplate heterodimer J-aggregates hybrid - 6066463.pdf
Creators: name: Hu, Zhiwei
name: Cui, Ximin
name: Li, Yang
name: Han, Xiaobo
name: hu, huatian
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement to manuscript
Ochterus manni Hungerford 1927
Creators: name: Peralta-Argomeda, Jorge Luis
name: Rodrigues, Juliana Mourão Dos Santos
name: Huamantinco-Araujo, Ana
name: Moreira, Felipe Ferraz Figueiredo
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Ochteridae
Ochterus
Ochterus manni

description: Ochterus manni Hungerford, 1927
 Geographic distribution. Costa Rica (Schell 1943), Panama (URS Holdings 2004), Brazil (D. Polhemus & J. Polhemus 2016), Ecuador (Cianferoni 2012), Peru (Schell 1943), Bolivia (Hungerford 1927).
 Distribution in Peru. San Martín (D. Polhemus & J. Polhemus 2016), unknown department (Schell 1943).
 Note. D. Polhemus & J. Polhemus (2016) suspected that O. unidentatus Nieser & Chen, 1992, described from Ecuador, could be a synonym of O. manni.
description: Published as part of Peralta-Argomeda, Jorge Luis, Rodrigues, Juliana Mourão Dos Santos, Huamantinco-Araujo, Ana & Moreira, Felipe Ferraz Figueiredo, 2024, Checklist of the aquatic and semiaquatic bugs (Hemiptera: Heteroptera: Gerromorpha, Leptopodomorpha & Nepomorpha) of Peru, pp. 1-72 in Zootaxa 5467 (1) on page 42, DOI: 10.11646/zootaxa.5467.1.1, http://zenodo.org/record/11613746
Temple of ʿAthtar dhū-Qabḍ
Creators: name: Agostini, Alessio
Publisher: name: Database of Religious History (DRH)
Year: 2022

description: This imposing religious edifice was built in the late 5th century BCE in the sacred area present within the ancient South Arabian urban site of Yathill (now uninhabited and known as Barāqish, present-day Yemen). It was dedicated to the god ʿAthtar dhū-Qabḍ, supreme deity of the Minaeans, the people who inhabited the Jawf valley of ancient Yemen during the first millennium BCE and who also occupied this settlement from the 6th century onward. This temple was built later than the adjoining one dedicated to the god Nakraḥ, with which it shares some design elements, such as the entrance staircase, the imposing propylaeum made of monolithic pillars more than six meters high, a hypostyle room divided into five naves and here organized into four inner cenacles. However, the differences are also significant: the adyton here features a central cella with two large accessory rooms on either side, and it is also possible that there was an upper floor, which made this building sensibly bigger than the adjoining one. Although the temple has been reused since antiquity, partly collapsed and then also heavily looted, it is still possible to appreciate the grandeur of its layout and the refinement of its interior furnishings, as for the four decorated offertory tables placed inside the cenacles. The first reuse occurred shortly after the end of the Minaean kingdom, around the first century CE, by the Arabian Amīr tribe, who nevertheless continued to use the temple for religious purposes, rededicating it to their god Ḥalfān. Excavations have unearthed dozens of inscriptions written in ancient Minaic, a South Arabian language of the Semitic phylum, as well as a few other pieces written in Sabaic and in the Amiritic variety. The building was occupied continuously for different purposes from the early Islamic period until the 17th-18th centuries CE, when the site was abandoned indefinitely.
Quantitation of Nitric Oxide in Cell Culture by Luciferin-Luciferase Chemiluminescence
Creators: name: Woldman, Yakov Y
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The chemiluminescent method is proposed for quantitation of NO generation in cell cultures grown on standard 96-well plates. The method is based on activation of soluble guanylyl cyclase by NO; the product of guanylyl cyclase reaction, pyrophosphate, after conversion to ATP by ATP sulfurylase, is detected in luciferin-luciferase system. The method has been applied to the measurement of NO generation by activated RAW 264.7 cells, primary bone-marrow murine macrophages and aortic endothelial cells. For macrophages, activated by lipopolysaccharide and γ−interferon, the rate of NO production is about 100 amol/(cell·min); the same rate was found from the measurements of nitrite, the final product of NO oxidation, for the same cells. For endothelial cells, the basal rate of NO generation is 5 amol/(cell·min); it approximately doubles upon activation by bradykinin, Ca2+ ionophore A23187 or mechanical stress (shaking). For both types of cells the measured NO generation is strongly affected by inhibitors of NO synthase. The sensitivity of the method is about 50 pM/min, allowing to measure NO generated by 102 – 104 cells. The direct comparison shows the chemiluminescent method to be two orders of magnitude more sensitive than fluorescent detection using DAF-FM.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Yoga and Meditation based intervention alters global genome expression profile in Primary Open Angle Glaucoma (POAG): Role in oxidative stress management.
Creators: name: Mohanty, Kuldeep
name: Faiq, Muneeb A
name: Dada, Rima
name: Dada, Tanuj
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objectives: Glaucoma is a neurodegenerative eye disorder often associated with elevated intraocular pressure (IOP)1.  A double blind randomized clinical trial was designed to investigate Yoga and Meditation Based Intervention (YMBI)  as a  modulator of global expression profile of genes in POAG patients.
Methods: Intervention was a three week mindfulness based stress reduction (YMBI) course. Patients (n=80) were randomized to either YMBI group or the no YMBI group (control). Primary outcome was effect of meditation on global expression profile of genes. It was studied by microarray analysis and validation of important genes was done by Real Time PCR. Gene expression was compared between groups by ΔCt and 2-ΔΔCt method. Secondary outcome was to study the oxidative stress markers, reactive oxygen species (ROS) and total antioxidant capacity (TAC) along with IOP.
Results:
In the intervention group, 54 genes were upregulated and 56 downregulated significantly. There was a significant increase in the expression of antioxidant gene (MT1E), genes related to anti-inflammatory responses (IL2 & IL4), retinal ganglion cell (RGC) survival (NGFR), neuroprotection and maintainance of TM structure (FGFR1) and a significant decrease in the expression of genes involved in neuroapoptosis (BCL2L11), neuroinflammation (MAPK10 & MAPK15) and IOP elevation (EGFR) post YMBI. There was no change in the expression of these genes in the control group. More than 50% of the patients in the YMBI group showed more than 2 fold change in the expression of these genes. There was a significant elevation in total antioxidant capacity and decrease in the ROS and IOP after the YMBI course.

Conclusion: A short term YMBI positively modified the expression pattern of genes involved in major pathologies involved in glaucoma i.e. oxidative stress, neuroinflammation, RGC apoptosis and dysregulation of aqueous humour outflow and YMBI was associated with reduction in oxidative stress and IOP in POAG patients.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
Could we use antioxidants during cancer chemotherapy or not?
Creators: name: Barzegari, Abolfazl
name: Omidi, Yadollah
name: Nouri, Mohammad
name: Letourneur, Didier
name: Pavon-Djavid, Graciela
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Drug resistance in cancer chemotherapy and the side effects represent a major obstacle to successful treatment of cancer (1). Chemotherapeutics through different mechanisms kill cancers; however they induce oxidative stress and cause side effects in normal cells(2). Some research has proved influence of antioxidants in reducing side effects, however a reduction in chemodrug efficiancy was also observed(3). ROS signaling could be different in various cancers or cellular behavior could be different against ROS and accordingly their treatment with chemotherapeutics or the antioxidant consumption would differ. This research was focused on these aspects to sort out the relationship between ROS and drug resistance in several cancer cell lines and the effect of antioxidants on drug resistance. MCF7, A549, HT29, CaCo-2, Caov-3, KB, and normal HUVECs were studied. 5-FU  as anti-tumor agent and Luperox as stressor, and Crocin and vitamin C as antioxidants were used. The cell signaling of Nrf2/HO1/NQO1 and PTEN/AKT were followed. Our results showed cancer cells could be categorized into two groups regarding the oxidative stress response. The use of antioxidants during chemotherapy could increase the efficiency of the chemotherapy and reduce the side effects or result in vein.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
D8.3 – Highlights of the value-chain events
Creators: name: Alexopoulou
Publisher: name: Zenodo
Year: 2021
Subjects: Biobased
biomass
crops
industrial crops
marginal lands

description: Report on both online MAGIC value-chain events
 Two on-line value chain events had been organished in collaboration with MAGIC project. The events had been organished on web due to COVID-19 crisis; the first took place on 17th of December 2020 and the second on 20th of January 2021.
The comparison of ROS signaling and antioxidant defense mechanisms in Mesenchymal stem cell, cancer cell, and normal cell
Creators: name: Ilghami, Roghayeh
name: Mashayekhi, Mohammad Reza
name: Barzegari, Abolfazl
name: Letourneur, Didier
name: Pavon-Djavid, Graciela
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: ROS homeostasis greatly contributes to stem cell self-renewal and differentiation, cancer development, and normal cell biofunction. The imbalance between the production of ROS and its neutralization is called oxidative stress (1), which was shown to be involved in the pathogenesis of many diseases(2-4). Tissues are different in the modest level of ROS required for their bioactivity. Therefore, if proper cellular level of ROS could be determined, accordingly the use of antioxidant to counteract oxidative stress could be decided. The aim of this study was the comparison of ROS defense cell signaling (Nrf2/HO1 and PTEN/Akt pathways) in cancer cells, Mesenchymal stem cells, and normal huvec cells. Cells were treated with different concentrations of luperox and cells’ growth and apoptosis and Nrf2/HO1 and PTEN/Akt pathways were studied in different time intervals. Our results showed that ROS affects cell lines in different manners and cell signaling is not induced in the same way. Therefore, the use of antioxidant may depend on the type of cell and the aim of their application. Our results could suggest purposeful application of antioxidants for reduction of side effects from chemotherapies, and regeneration of injured tissues, as well as in predictive medicine.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)
The short term effects of cigarette cessation on oxidative stress related blood parameters
Creators: name: Bicer, Cemile
name: Yuksel, Sevda
name: Cucen, Zubeyde
name: Sengezer, Tijen
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Aim: In Turkey despite the government’s tobacco control policies, smoking and related health problems like COPD is one of the major leading health issue. In our study we evaluated the acute effects of quitting smoking on blood defence system against oxidative stress.

 Methods: 50 smokers were enrolled in the study however only 30 of them succeeded in maintaining 3 months quitting and became the study group. The cigarette count per day was between 10 to 40 and duration of smoking was 5 to 37 years among participants. Whole blood count, uric acid, bilirubin, albumin, ferritin and thiol levels were measured before and after quitting.

 Results: A decreased percentage of neutrophils (p = 0.02) and eosinophils (p = 0.04), and increased percentage of lymphocytes (p = 0.01) was observed. Serum uric acid level and ferritin levels were significantly increased (p = 0.001 and p = 0.007 respectively). Albumin bilirubin and thiol levels were not changed statistically.

 Conclusion: Quitting smoking has positive effects on defense mechanism against oxidative stress even after 3 months of quitting period.

 Key words: smoking, oxidative status, WBC , antioxidants
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 3 (2016)