cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Al via le analisi dei frammenti dell’asteroide Ryugu
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2024

Un team tutto italiano composto da ricercatori e ricercatrici dell’Istituto nazionale di astrofisica, dell’Università di Firenze e dell’Istituto nazionale di fisica nucleare avvia le analisi dei due preziosissimi campioni dell'asteroide Ryugu ricevuti a maggio del 2023 nell’ambito di un bando internazionale per l’analisi dei materiali cosmici riportati a Terra dalla missione Hayabusa-2 dell’Agenzia spaziale giapponese Jaxa
A Systematic Review of Occupational Exposure to Hydrogen Sulfide in Livestock Operations
Creators: name: Justene Guarrasi
name: Trask, Catherine
name: Kirychuk, Shelley
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences

description: ABSTRACTThis systematic review summarizes the current state of knowledge in hydrogen sulfide (H2S) concentrations within intensive livestock operations. The review was undertaken to better understand H2S concentrations in intensive livestock operations, in relation to the American Conference of Governmental Industrial Hygienists (ACGIH) limit reduction to a 1 ppm time-weighted average (TWA). Several online academic databases were searched using two conceptual groups of search terms: “livestock” and “hydrogen sulfide.” Industry gray literature was additionally identified via targeted searches of online agriculture-specific Web sites. Title, abstract, and full-text screening were performed to select articles reporting H2S measurements made within livestock facilities. Forty-five articles were included in this review. The bulk (70%) of articles described swine operations, whereas the remaining represented poultry and dairy operations. Although 14% of the articles described task-based monitoring of H2S, the majority of articles (86%) involved only area monitoring. Weighted means from all three livestock types were below 1 ppm, although swine operations displayed a wider range of exposure (from 0 to 97 ppm). Despite most mean task-based exposures being close to 1 ppm, the peak concentrations measurements may be higher during power washing (97 ppm) and miscellaneous tasks (11.4 ppm). This review provides a novel overview of H2S levels in intensive livestock operations, including information on task-based measurements. The review highlights numerous influences that produce a wide variability of H2S levels in intensive livestock operations. The review also highlights the need for research focused on personal monitoring of daily worker exposures to hydrogen sulfide in intensive livestock operations.
Le millecinquecento supernove Ia di Des
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2024

La collaborazione internazionale Dark Energy Survey (Des) ha ottenuto il più grande campione di supernove mai realizzato da un singolo telescopio. Analizzando le circa 1500 supernove Ia del campione, ha posto i vincoli più stringenti di sempre ai parametri che caratterizzano l'espansione cosmica utilizzando queste candele standard e ha trovato indizi che la densità di energia oscura dell'universo possa variare nel tempo
Doppia esplosione nella Grande Nube di Magellano
Creators: Valentina Guglielmo
Publisher: name: Media Inaf
Year: 2024

Un’immagine multicromatica che contiene due esplosioni di supernova in una regione di formazione stellare. Una avvenuta circa cinquemila anni fa, responsabile di un’emissione a raggi X più brillante e circoscritta, e una precedente, che ha prodotto un’emissione estesa alla stessa lunghezza d’onda
Sn 1987A, un resto di supernova per Xrism
Creators: Mario Guarcello
Publisher: name: Media Inaf
Year: 2024

Simulate le osservazioni dell’iconico resto di supernova Sn 1987A che realizzerà lo strumento Resolve del telescopio spaziale giapponese Xrism. Lo studio, guidato da Vincenzo Sapienza dell’Università di Palermo, dimostra le notevoli capacità di Xrism nel fornire una profonda comprensione dei processi fisici ed evolutivi di Sn 1987A e, più in generale, nei resti di supernova
Urano e Nettuno senza fotoritocchi
Creators: Chiara Badia
Publisher: name: Media Inaf
Year: 2024

Ce li hanno sempre mostrati uno verde pallido, l’altro blu intenso. Ma in realtà i colori di Urano e Nettuno non sono così diversi. Una ricerca condotta dall’Università di Oxford ha rivelato che i due giganti ghiacciati hanno una tonalità blu-verde molto simile, mettendo fine a decenni di controversie sulle differenze cromatiche apparenti. Il team ha anche fornito una spiegazione agli insoliti cambiamenti stagionali del colore di Urano, dovuti alla concentrazione di metano ai poli
La stretta dell’ossigeno sulle tecnovite
Creators: Giuseppe Fiasconaro
Publisher: name: Media Inaf
Year: 2024

La percentuale di ossigeno in atmosfera potrebbe essere il collo di bottiglia per l'ascesa di civiltà in grado di produrre segni rivelatori di intelligenza extraterrestre. È quanto suggerisce uno studio pubblicato su Nature Astronomy. «Se non si supera la strettoia dell'ossigeno, la vita, anche intelligente, non può iniziare a salire i gradini dello sviluppo tecnologico», dice a Media Inaf Amedeo Balbi, uno dei due autori della ricerca
Un “mostro verde” fra i detriti di Cassiopea A
Creators: Laura Leonardi
Publisher: name: Media Inaf
Year: 2024

Mettendo insieme i dati di Chandra e del telescopio spaziale James Webb, uno studio guidato dalla Purdue University ha scoperto nuovi dettagli sui resti della stella che ha generato l'esplosione di Cassiopea A. Le immagini sono state presentate oggi alla conferenza stampa della American Astronomical Society. Con un commento di Danny Milisavljevic della Purdue University e di Salvatore Orlando dell’Inaf di Palermo
Meteorite Renazzo, due secoli di scienza e misteri
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2024

La sera del 15 gennaio 1824 una meteorite carbonacea cadde su Renazzo, paese natale di Ferruccio Lamborghini, al confine fra le province di Ferrara e Bologna. Numerosi frammenti furono ritrovati, consentendo di datarne l'origine a un’epoca antichissima, precedente la formazione del Sistema solare. Sabato 13 e domenica 14 gennaio il Comune di Cento, in provincia di Ferrara, ospiterà una ricca serie d’iniziative per celebrare il bicentenario dell’evento
Missione Xrism, ecco il primo sguardo sul cosmo
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2024

La missione Xrism (X-ray Imaging and Spectroscopy Mission), guidata dalla giapponese Jaxa, ha dato una prima occhiata ai dati che raccoglierà quando le operazioni scientifiche avranno inizio, nel corso di quest’anno. Il team scientifico del satellite ha pubblicato un'istantanea di un ammasso di centinaia di galassie e uno spettro con un dettaglio attualmente senza precedenti di un resto di supernova in una galassia vicina
Nella Città del Sole, delle Api e delle Stelle
Creators: Giangiacomo Gandolfi
Publisher: name: Media Inaf
Year: 2024

Parte a gennaio un ciclo mensile di incontri e visite ispirato alla mostra “La città del Sole. Arte barocca e pensiero scientifico nella Roma di Urbano VIII”, in corso fino all’11 febbraio a Palazzo Barberini. Organizzata da Inaf, Museo Galileo e Università La Sapienza la serie di eventi invita i cittadini a vivere l’esperienza della mostra e a seguire le tracce delle “Api Urbane”, dal Collegio Romano all’Osservatorio astronomico di Monte Mario e Monte Porzio
Corsa alla Luna, è l’ora del Giappone
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2024

Ormai ci siamo: fra due settimane, venerdì 19 gennaio, il lander Slim della Jaxa tenterà un atterraggio morbido sul suolo lunare. Un’impresa che per ora è riuscita solo all’Unione Sovietica, agli Stati Uniti, alla Cina e all’India – il Giappone potrebbe dunque diventare il quinto paese ad avercela fatta. L’intenzione dei responsabili della missione è di compiere un approdo di altissima precisione nei pressi del piccolo cratere Shioli, sulla faccia della Luna a noi visibile
Ricetta per un’insalata spaziale
Creators: Chiara Badia
Publisher: name: Media Inaf
Year: 2024

Le prossime missioni a lungo termine per l’esplorazione umana dello spazio avranno bisogno di un approvvigionamento consistente di risorse per gli astronauti. Dopo i vari esperimenti sulle coltivazioni nello spazio, ora i ricercatori si sono concentrati su come fornire agli equipaggi cibo nutriente, ma anche fresco, gustoso e sostenibile, proveniente da “fattorie spaziali”. Combinando le diverse esigenze, si è così giunti alla ricetta del “piatto perfetto”
Molto ozono e poca CO2, la firma della vita altrove
Creators: Giuseppe Fiasconaro
Publisher: name: Media Inaf
Year: 2024

Secondo uno studio pubblicato su Nature Astronomy e condotto da un team di ricerca guidato dall'Università di Birmingham, nel Regno Unito, l’indicatore più efficace della presenza di acqua liquida sugli esopianeti è l'anidride carbonica. Misurabili facilmente con Jwst, quantità relativamente ridotte della molecola nell’atmosfera d’un pianeta roccioso, insieme all’abbondanza di ozono, sarebbero la chiave per individuare mondi abitabili e potenzialmente abitati
Ammassi stellari a volontà nel cielo di gennaio
Creators: Fabrizio Villa
Publisher: name: Media Inaf
Year: 2024

Il cielo di questo mese ci offre un ricco bottino di ammassi stellari aperti visibili con un binocolo e anche ad occhio nudo. È anche tempo di Quadrantidi, uno sciame meteorico il cui picco è previsto per giovedì 4 e che può riservare qualche sorpresa. Le belle costellazioni invernali fanno da sfondo a Giove che anche questo mese, insieme al mattiniero Venere, sono i due pianeti più facilmente visibili in gennaio
Eros o BluDogs? Così è il colore dei futuri quasar
Creators: Laura Leonardi
Publisher: name: Media Inaf
Year: 2024

Come una farfalla deve lacerare il rivestimento della crisalide per poter spiccare il volo, così un quasar deve spazzar via la polvere che lo avvolge per poter risplendere. Osservando con i telescopi Webb e Subaru due tipi di “crisalidi di quasar” – due classi di galassie, una con dominante rossa e l'altra blu, ritenute quasar in transizione – un team di ricercatori giapponesi ha ora scoperto che appartengono alla stessa classe di oggetti, seppure in diverse fasi evolutive
Guardi il cielo e accendi la “macchina del tempo”
Creators: Patrizia Caraveo
Publisher: name: Media Inaf
Year: 2024

L’astronomia è una “macchina del tempo”, come recita il titolo della mostra – visitabile fino al 24 marzo – ideata dall’Istituto nazionale di astrofisica, in collaborazione con Pleiadi srl, negli spazi del Palazzo delle Esposizioni di Roma. Con il consenso dell’autrice, l’astrofisica Patrizia Caraveo, vi riproponiamo la recensione pubblicata domenica scorsa sul Sole24Ore
Webb, bis di supernove con una lente gravitazionale
Creators: Federica Loiacono
Publisher: name: Media Inaf
Year: 2024

Due supernove nella stessa galassia a distanza di pochi anni. È la prima volta che due eventi di questo tipo vengono osservati nella stessa galassia sfruttando il fenomeno del lensing gravitazionale. Le immagini multiple delle supernove dovute al lensing e il ritardo fra i tempi d’arrivo della loro luce consentiranno di misurare la costante di Hubble. La scoperta è stata compiuta grazie ai telescopi Hubble e Webb
Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis
Creators: name: Cabrera, Sandra
name: Maciel, Mariana
name: Herrera, Iliana
name: Nava, Teresa
name: Fabián Vergara
name: Gaxiola, Miguel
name: López-Otín, Carlos
name: Selman, Moisés
name: Pardo, Annie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and proteins. Impaired autophagic activity is involved in a number of diseases, including idiopathic pulmonary fibrosis suggesting that altered autophagy may contribute to fibrogenesis. However, the specific role of autophagy in lung fibrosis is still undefined. In this study, we show for the first time, how autophagy disruption contributes to bleomycin-induced lung fibrosis in vivo using an Atg4b-deficient mouse as a model. Atg4b-deficient mice displayed a significantly higher inflammatory response at 7 d after bleomycin treatment associated with increased neutrophilic infiltration and significant alterations in proinflammatory cytokines. Likewise, we found that Atg4b disruption resulted in augmented apoptosis affecting predominantly alveolar and bronchiolar epithelial cells. At 28 d post-bleomycin instillation Atg4b-deficient mice exhibited more extensive and severe fibrosis with increased collagen accumulation and deregulated extracellular matrix-related gene expression. Together, our findings indicate that the ATG4B protease and autophagy play a crucial role protecting epithelial cells against bleomycin-induced stress and apoptosis, and in the regulation of the inflammatory and fibrotic responses.
ETL Workflow Modeling
Creators: name: Tiwari, Abhishek
Publisher: name: Abhishek-Tiwari.Com
Year: 2018

description: Developing Extract–transform–load (ETL) workflow is a time-consuming activity yet a very important component of data warehousing process. The process to develop ETL workflow is often ad-hoc, complex, trial and error based. It has been suggested that formal modeling of ETL process can alleviate most of these pain points. Generally speaking, formal modeling can reduce implementation time and save money by adopting structural patterns and best-practices when implementing ETL workflows.
Superior mesenteric artery syndrome secondary to thyrotoxicosis
Creators: name: Jacobs, Abigail
name: Pacheco, Tulio Brasileiro Silva
name: Sohail, Amir
name: Goparaju, Anirudha
Publisher: name: PRIME
Year: 2024
Subjects: classificationCode: 320226
subject: Surgery

description: AbstractSuperior mesenteric artery (SMA) syndrome is defined as a narrowed space and decreased angle between the SMA and aorta leading to partial or complete obstruction of the third portion of the duodenum. SMA syndrome patients may have comorbid conditions associated with extreme weight loss, hypermetabolism or malnutrition. We present the case of a 55-year-old male with SMA syndrome due to acute weight loss secondary to thyrotoxicosis. The patient was nutritionally optimized and euthyroid prior to undergoing a robotic-assisted duodenojejunostomy. In this patient, the thyrotoxicosis was controlled medically, and he remained euthyroid postoperatively. His duodenal obstruction was relieved by the operation and he continued to gain weight appropriately.
Extracting Tritium from Water Using a Protonic Manganese Oxide Spinel
Creators: name: Koyanaka, Hideki
name: Miyatake, Hideo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Microbiology
subject: 60506 Virology
subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: Extracting tritium of parts-per-trillion-levels from water at room temperature was provided using a protonic manganese oxide with a spinel crystal structure under weakly acidic conditions. Indeed, using 0.48 g of the protonic manganese oxide powder led to the removal of 1.75 × 105 Bq of tritium in 20 min at room temperature from a test water (100 mL) that contained a tritium concentration of 5.6 × 106 Bq/L (i.e., 15.6 ng/L). The extraction capability of tritium significantly depended on the crystal structure of manganese oxides and the proton content in the spinel crystal structure.
Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis.
Creators: name: Cabrera, Sandra
name: Maciel, Mariana
name: Herrera, Iliana
name: Nava, Teresa
name: Fabián Vergara
name: Gaxiola, Miguel
name: López-Otín, Carlos
name: Selman, Moisés
name: Pardo, Annie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and proteins. Impaired autophagic activity is involved in a number of diseases, including idiopathic pulmonary fibrosis suggesting that altered autophagy may contribute to fibrogenesis. However, the specific role of autophagy in lung fibrosis is still undefined. In this study, we show for the first time, how autophagy disruption contributes to bleomycin-induced lung fibrosis in vivo using an Atg4b-deficient mouse as a model. Atg4b-deficient mice displayed a significantly higher inflammatory response at 7 days after bleomycin treatment associated with increased neutrophilic infiltration and significant alterations in proinflammatory cytokines. Likewise, we found that Atg4b disruption resulted in augmented apoptosis affecting predominantly alveolar and bronchiolar epithelial cells. At 28 days post-bleomycin instillation Atg4b-deficient mice exhibited more extensive and severe fibrosis with increased collagen accumulation and deregulated extracellular matrix-related gene expression. Together, our findings indicate that the ATG4B protease and autophagy play a crucial role protecting epithelial cells against bleomycin-induced stress and apoptosis, and in the regulation of the inflammatory and fibrotic responses.
THE HIDDEN DANGER: DIAPORTHE PARANAENSIS AS A CATALYST FOR FRUIT ROT IN PEACH ORCHARDS
Creators: name: Maria, Elena Souza
name: Fernando, Luís Costa
name: Juliana, Beatriz Oliveira
Publisher: name: Continental Journal
Year: 2024
Subjects: Peach fruit, Post-harvest deterioration, Rot incidence, Preservation, Quality improvement'

description: Peach (Prunus persica) holds a significant position as the third most vital temperate fruit crop globally, following apple and pear trees. In 2019, Brazil emerged as a notable contributor to peach production, yielding 183.1 thousand tons within approximately 16 thousand hectares, with Rio Grande do Sul leading the pack at 110.2 thousand tons and São Paulo following closely with 32.9 thousand tons. However, peaches, being among the temperate fruits, possess a high susceptibility to spoilage due to their rapid post-harvest metabolism, resulting in quick loss of pulp firmness, rot, and withering. This accelerated ripening process curtails their shelf life, thus imposing substantial limitations on effective handling and transportation. Common culprits responsible for the rot of peaches include Monilinia fructicola, Penicillium, Rhizopus, Fusarium, Colletotrichum, Cladosporium, and Geotrichum.

This paper delves into the challenges faced by the peach industry, focusing on the rapid deterioration of peach fruit post-harvest, and the associated incidence of rot. By analyzing the factors contributing to these issues and exploring potential solutions, this study seeks to enhance the preservation, transportation, and overall quality of peach produce.
Diel Patterns and Temporal Trends in Spawning Activities of Robust Redhorse and River Redhorse in Georgia, Assessed Using Passive Acoustic Monitoring
Creators: name: Straight, Carrie A.
name: C. Rhett Jackson
name: Freeman, Byron J.
name: Freeman, Mary C.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Meta Science
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Evolutionary Biology

description: The conservation of imperiled species depends upon understanding threats to the species at each stage of its life history. In the case of many imperiled migratory fishes, understanding how timing and environmental influences affect reproductive behavior could provide managers with information critical for species conservation. We used passive acoustic recorders to document spawning activities for two large-bodied catostomids (Robust Redhorse Moxostoma robustum in the Savannah and Broad rivers, Georgia, and River Redhorse M. carinatum in the Coosawattee River, Georgia) in relation to time of day, water temperature, discharge variation, moonlight, and weather. Robust Redhorse spawning activities in the Savannah and Broad rivers were more frequent at night or in the early morning (0100–0400 hours and 0800–1000 hours, respectively) and less frequent near midday (1300 hours). Spawning attempts in the Savannah and Broad rivers increased over a 3–4-d period and then declined. River Redhorse spawning activities in the Coosawattee River peaked on the first day of recording and declined over four subsequent days; diel patterns were less discernible, although moon illumination was positively associated with spawning rates, which was also observed for Robust Redhorses in the Savannah River. Spawning activity in the Savannah and Broad rivers was negatively associated with water temperature, and spawning activity increased in association with cloud cover in the Savannah River. A large variation in discharge was only measured in the flow-regulated Savannah River and was not associated with spawning attempts. To our knowledge, this is the first study to show diel and multiday patterns in spawning activities for any Moxostoma species. These patterns and relationships between the environment and spawning activities could provide important information for the management of these species downstream of hydropower facilities.Received July 9, 2014; accepted December 10, 2014
Extracting Tritium from Water Using a Protonic Manganese Oxide Spinel
Creators: name: Koyanaka, Hideki
name: Miyatake, Hideo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Microbiology
subject: 60506 Virology
subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: ABSTRACTExtracting tritium of parts-per-trillion-levels from water at room temperature was provided using a protonic manganese oxide with a spinel crystal structure under weakly acidic conditions. Indeed, using 0.48 g of the protonic manganese oxide powder led to the removal of 1.75 × 105 Bq of tritium in 20 min at room temperature from a test water (100 mL) that contained a tritium concentration of 5.6 × 106 Bq/L (i.e., 15.6 ng/L). The extraction capability of tritium significantly depended on the crystal structure of manganese oxides and the proton content in the spinel crystal structure.
AVALIAÇÃO DOS INDICADORES DO ARRANJO PRODUTIVO LOCAL DA PISCICULTURA NO TOCANTINS
Creators: name: Hemerson Leandro Carvalho de HOLANDA
name: Alysson Soares da ROCHA
Publisher: name: Zenodo
Year: 2024
Subjects: Arranjo Produtivo Local
Indicadores
Piscicultura

description: RESUMO

 

Este trabalho teve como objetivo a avaliação dos indicadores do arranjo produtivo local da piscicultura do estado do Tocantins, com coleta de dados institucionais de órgãos públicos, empresas privadas e base de dados da internet. Os Arranjos Produtivos Locais (APLs) são aglomerações territoriais de agentes econômicos, políticos e sociais com foco em um conjunto específico de atividades econômicas que apresentam vínculos de empresa. Suas várias formas de representação e associações, como também de diversas outras instituições públicas e privadas, são voltadas para a formação e capacitação de recursos humanos, pesquisa, desenvolvimento, engenharia, política, promoção e financiamento. Incluem-se, portanto, universidades, instituições de pesquisa, empresas de consultoria e de assistência técnica, órgãos públicos, organizações privadas e não governamentais. É sugerida uma visão sistêmica da atividade produtiva e inovativa, considerando-se assim toda uma multiplicidade de atores econômicos, políticos e sociais que contribuem para dar contornos específicos às atividades desenvolvidas neste ambiente. A piscicultura é o ramo da aquicultura voltado ao cultivo de peixes em cativeiro. Atualmente essa atividade é vista como uma nova opção de agronegócio e está inserida no meio rural, dividindo espaço com a agricultura e pecuária. Considerada por muitos como uma atividade que impulsiona o desenvolvimento social e econômico do país e região, a piscicultura é uma das principais atividades de sustento para a agricultura familiar. Desse modo verificou-se que a aplicação de indicadores para o APL da piscicultura do estado demanda estudos aprofundados com uma vasta base de dados acessíveis para melhor avaliação de todos os fatores envolvidos na cadeia.
Biz4EYE A project for the “Erasmus for Young Entrepreneurs” European Programme
Creators: name: Boém, Marika Mazzi
name: Laquidara, Giuseppe
Publisher: name: figshare
Year: 2015
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Economics
subject: Education

description: Basing on the Erasmus for Entrepreneurs Programme overall objectives to facilitate young entrepreneurs’ access to on-the- job transnational training, to enhance entrepreneurship culture and encourage cross-border training in Europe, Biz4EYE project will promote entrepreneurship to allow young entrepreneurs to practice business in real scenario, supporting them in the creation and development of their companies. The main goal of the Biz4EYE project is to further implement the EYE programme locally, thus broadening the existing network of Intermediary Organizations and offering potential business opportunities both to new entrepreneurs as well as to experienced ones. The specific objectives will be to promote the project on a national/regional/local level, stimulating engagement and participation, recruiting potential applicants and assisting them during before/during- after the mobility period. The project will be addressed to young entrepreneurs who are firmly convinced to start a business (providing a substantiated Business Plan) or are in the business for less than 3 years but in the need to grow; and to successful entrepreneurs in the business for at least 3 years. Though the EYE programme is open to everyone active in different market sectors, Biz4EYE project will focus in particular on creative enterprises, considered a powerful engine for the economic development of the EU market. Biz4EYE project actions will focus on enhancing and stimulating entrepreneurship locally; facilitating international outlook; increasing the competitiveness of the participant countries’ entrepreneurs (I, PT, LV, PL, FI) within the creative and cultural market sector.
Single nucleotide variant detection in Jaffrabadi buffalo (Bubalus bubalis) using high-throughput targeted sequencing
Creators: name: Maulik R. Upadhyay
name: Patel, Anand B.
name: Subramanian, Ramalingam B.
name: Tejas M. Shah
name: Jakhesara, Subhash J.
name: Vaibhav D. Bhatt
name: Koringa, Prakash G.
name: Dharamshibhai N. Rank
name: Chaitanya G. Joshi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Information and Computing Sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Genetics
subject: Cell Biology

description: The water buffalo is among the most important livestock species of southern Asia, contributing greatly to the ecosystem and rural livelihood of the region. The identification of large-scale single nucleotide polymorphisms in this species would greatly facilitate our understanding of the genetic basis of economically important traits such as milk production, fertility traits and general health traits. The present study investigated the cost-effective method of exome capture and single nucleotide variant (SNV) identification from genomic DNA of Jaffrabadi buffalo using biotin-labelled cDNA as probes. Sequencing of enriched fragments generated 608 Mb of data, which was mapped to a Bos taurus genome assembly followed by variant calling and annotation. Furthermore, 393 coding SNVs were identified, leading to 143 non-synonymous substitutions (nsSNVs) in 75 genes. Of the 75 nsSNV-containing genes, four matched the genes that have previously been reported to be potentially associated with economically important traits such as milk production and meat production. Furthermore, functional annotation using gene ontology (GO) enrichment identified categories such as glutamate receptor activity (GO: 0008066) enriched in the fertility trait samples. These results provide a framework for the application of cost-effective methods of target capture in SNV detection from non-model organisms such as the water buffalo.
Quantitative structure–activity relationship study on BTK inhibitors by modified multivariate adaptive regression spline and CoMSIA methods
Creators: name: A. Xu
name: Y. Zhang
name: T. Ran
name: H. Liu
name: S. Lu
name: J. Xu
name: X. Xiong
name: Y. Jiang
name: T. Lu
name: Y. Chen
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Chemistry
Earth and Environmental Sciences
Pharmacology
Cell Biology
Engineering

description: Bruton’s tyrosine kinase (BTK) plays a crucial role in B-cell activation and development, and has emerged as a new molecular target for the treatment of autoimmune diseases and B-cell malignancies. In this study, two- and three-dimensional quantitative structure–activity relationship (2D and 3D-QSAR) analyses were performed on a series of pyridine and pyrimidine-based BTK inhibitors by means of genetic algorithm optimized multivariate adaptive regression spline (GA-MARS) and comparative molecular similarity index analysis (CoMSIA) methods. Here, we propose a modified MARS algorithm to develop 2D-QSAR models. The top ranked models showed satisfactory statistical results (2D-QSAR: Q2 = 0.884, r2 = 0.929, r2pred = 0.878; 3D-QSAR: q2 = 0.616, r2 = 0.987, r2pred = 0.905). Key descriptors selected by 2D-QSAR were in good agreement with the conclusions of 3D-QSAR, and the 3D-CoMSIA contour maps facilitated interpretation of the structure–activity relationship. A new molecular database was generated by molecular fragment replacement (MFR) and further evaluated with GA-MARS and CoMSIA prediction. Twenty-five pyridine and pyrimidine derivatives as novel potential BTK inhibitors were finally selected for further study. These results also demonstrated that our method can be a very efficient tool for the discovery of novel potent BTK inhibitors.
Benefits and problems of fungicide control of Botrytis cinerea in vineyards of Champagne
Creators: name: Couderchet, M.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: There are several agrochemicals to control Botrytis cinerea, the causal agent for gray mold in grapes, and new ones are being developed. The fungicides used to control Botrytis in vineyards of the Champagne are presented together with some of their deleterious effects on non-target species. Until recently, fungicides basically belonged to three groups: the carbamates, the benzimidazoles, and the cyclic imides. Treatments with these fungicides rapidly became inefficient because of the extreme variability observed within the pathogen. In the last 10 years, new chemicals such as pyrimethanil, fludioxonil, fluazinam, and fenhexamid, all from different chemical groups became available; until now Botrytis displayed no resistance to these chemicals in the Champagne. The problem of residues in wine and in the environment, including their deleterious effects on non-target organisms, as well as acute and sublethal toxicity of the fungicides are discussed. Solutions to limit environmental contamination are presented.
description: VITIS - Journal of Grapevine Research, Vol. 42 No. 4 (2003): Vitis
A method using leafed single-node cuttings to evaluate downy mildew resistance in grapevine
Creators: name: Liu, S. M.
name: Sykes, S. R.
name: Clingeleffer, P. R.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: A method using leafed single-node cuttings, incubated at 25 ± 2 °C and 100 % humidity, was examined to screen grapevine genotypes for resistance to downy mildew (Plasmopara viticola (Bert. & Curt.) Berl. & de Toni). Cuttings were taken at the 4th, 5th and 6th nodes back from apices of actively growing shoots. Disease symptoms, namely chlorosis, sporulation and necrosis, were observed on the leaves of cuttings within 6 days of incubation after inoculation. Based on chlorosis and sporulation, genotypes were ranked from highly susceptible to resistant in the order of Sultana, M46-32 (Bicane x Villard blanc), Joannes Seyve 23.416, Marroo Seedless and Chambourcin. The expressions of both symptoms increased with the concentration of inocula applied to leaves (1 x 105 and 5 x 104 sporangia per ml), but the overall genotypic ranking was unaltered. The third symptom of leaf necrosis occurred on infected leaves either as progressively enlarging dead areas or as smaller localised necrotic spots. The latter has been call ed the ‘necrotic response’ symptom and its expression depended on genotype, although its value for separating or ranking genotypes was unreliable. Leaf chlorosis was associated with leaf sporulation (r2=0.41-0.47). Genotypes with necrotic response exhibited reduced leaf chlorosis and sporulation. A comparison between this new leafed singlenode cutting method and a previously published leaf disc method indicated it was more reliable for separating genotypes for downy mildew resistance.
description: VITIS - Journal of Grapevine Research, Vol. 42 No. 4 (2003): Vitis
Molecular identification of a phytoplasma infecting grapevine in the Republic of Macedonia
Creators: name: Šeruga, M.
name: Škorić, D.
name: Kozina, B.
name: Mitrev, S.
name: Krajačić, M.
name: Ćurković Perica, M.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Phytoplasmas from the ribosomal subgroup 16SrXII-A (stolbur) were identified by PCR and RFLP analyses of 16S rRNA gene and elongation factor-Tu phytoplasma gene (tuf) in symptomatic grapevines from the Veles and Skopje areas in Macedonia. Two methods were used for nucleic acid extraction. Amplification and RFLP results of 16S rDNA were not influenced by the method used, but RFLP patterns of tuf gene revealed additional bands if a less time consuming method was applied. The possible origin of these bands is discussed. This is the first report of the presence of the stolbur phytoplasma in cvs Chardonnay and Vranac in Macedonia.
description: VITIS - Journal of Grapevine Research, Vol. 42 No. 4 (2003): Vitis
Characterization of Iranian grapevine cultivars using microsatellite markers
Creators: name: Fatahi, R.
name: Ebadi, A.
name: Bassil, N.
name: Mehlenbacher, S. A.
name: Zamani, Z.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Sixty-two grapevine (Vitis spp.) accessions from Iran and the USA were characterized at 9 highly polymorphic microsatellite loci using fluorescent primers and a capillary electrophoresis fragment sizing system. The number of alleles observed per locus ranged from 4 to 16 and heterozygosity values ranged from 0.47 to 0.86. Genetic similarity was estimated for each pair of accessions as the proportion of shared alleles. A phenogram constructed from genetic dissimilarity values revealed three clusters, one each for table grapes, wine grapes and rootstocks. The phenogram also revealed three clonal sets (Askari, Bidane and Yaghoti) as well as some synonyms and homonyms among Iranian table grape cultivars.
description: VITIS - Journal of Grapevine Research, Vol. 42 No. 4 (2003): Vitis
The parentage of Muscat of Hamburg
Creators: name: Crespan, M.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: This research demonstrates that Muscat of Hamburg, a fine black table grape variety with muscat flavour, is the progeny of Schiava Grossa x Muscat of Alexandria. Two isozymes (GPI and PGM), 30 nuclear and 5 chloroplastic microsatellite markers were used. Two highly informative microsatellite markers from VMC (‘Vitis Microsatellite Consortium’) are suggested to enlarge the minimum set of loci selected for grapevine identification in the frame of the European Project GenRes 081.
description: VITIS - Journal of Grapevine Research, Vol. 42 No. 4 (2003): Vitis
FREYA webinar on the NARCIS PID Graph - 9/4/2020
Creators: name: Braukmann, Ricarda
name: Baars, Chris
Publisher: name: Zenodo
Year: 2020
Subjects: FREYA
NARCIS
PID

description: NARCIS is the national portal for scientific information in the Netherlands hosted by DANS. NARCIS provides access to scientific information, including (open access) publications, datasets, as well as descriptions of research projects, scientists, and research institutes. Persistent Identifiers (PIDs) that unambiguously identify a given digital object, person or institute play an important role in our infrastructure. Within the FREYA project, DANS has worked to include new PIDs (e.g. ROR) in NARCIS and constructed a NARCIS PID Graph. The PID Graph can be used to enrich NARCIS with information located in other portals through connecting the relevant PIDs.
Lewis base adducts of diisobutylaluminum azide: synthesis and thermal stability
Creators: name: Bennae, Kenneth T.
name: Powell, Douglas R.
name: Wehmschulte, Rudolf J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Developmental Biology
subject: Information and Computing Sciences
subject: Chemistry
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Diisobutylaluminum azide was prepared from the reaction of diisobutylaluminum hydride with trimethylsilyl azide, and it was reacted with five different Lewis bases. The monodentate ligands p-dimethylaminopyridine (DMAP) and the two N-heterocyclic carbenes IMes and IDipp afforded the expected adducts L·Al(i-Bu)2N3 in good yields. Reaction with the bidentate diimine (MesN=CH)2 did not stop at the adduct stage, but continued to form the iminoamide compound {MesNCH2C(i-Bu)NMes}Al(i-Bu)N3 through formal Al-i-Bu addition to one of the N–C double bonds followed by i-Bu migration. The terdentate pincer ligand 2,6-bis(diethylaminomethyl)pyridine induces azide transfer and formation of the ionic compound [2,6-(Et2NCH2)2C5H3NAl(i-Bu)2][(i-Bu)2Al(N3)2]. The compounds are thermally stable to at least 110 °C but decompose either into their precursors or into a mixture of unidentified products. All new compounds were characterized by 1H and 13C{1H} spectroscopy, IR spectroscopy, and the iminoamide compound {MesNCH2C(i-Bu)NMes}Al(i-Bu)N3 was also analyzed by single-crystal X-ray diffraction.
Variation in crystalline architectures through supramolecular interactions in copper(II) complexes with tridentate N2O donor Schiff bases
Creators: name: Jana, Subrata
name: Partha Pratim Jana
name: Shouvik Chattopadhyay
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Chemistry
Earth and Environmental Sciences
Molecular Biology
Cell Biology
Physics
Biochemistry
Biophysics

description: Three copper(II) complexes, [Cu(L1)(H2O)(ClO4)]·0.5H2O (1), [Cu(L2)(H2O)(ClO4)]·0.5H2O (2), and [Cu(L2)(NCNC(OCH3)NH2)]ClO4 (3), where HL1 = 4-bromo-2-(-(quinolin-8-ylimino)methyl)phenol and HL2 = 1-(-(quinolin-8-ylimino)methyl)naphthalen-2-ol, have been prepared and characterized by elemental analysis, IR, UV–vis and fluorescence spectroscopy and single-crystal X-ray diffraction studies. The copper(II) centers assume five-coordinate square-pyramidal geometries in 1 and 2, whereas square planar copper(II) is present in 3. A methanol molecule has been inserted in the pendant end of the ligated dicyanamide in 3. Various supramolecular architectures are formed by hydrogen bonding, π⋯π, C–H⋯π, and lp⋯π interactions.
Kinetics and mechanism of the substitution reactions of some monofunctional Pd(II) complexes with different nitrogen-donor heterocycles
Creators: name: Kosović, Milica
name: Željko Jaćimović
name: Živadin D Bugarčić
name: Petrović, Biljana
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Chemistry
subject: Molecular Biology
subject: Biochemistry
subject: Biophysics

description: Substitution reactions of five monofunctional Pd(II) complexes, [Pd(terpy)Cl]+ (terpy = 2,2′;6′,2″-terpyridine), [Pd(bpma)Cl]+ (bpma = bis(2-pyridylmethyl)amine), [Pd(dien)Cl]+ (dien = diethylenetriamine or 1,5-diamino-3-azapentane), [Pd(Me4dien)Cl]+ (Me4dien = 1,1,7,7-tetramethyldiethylenetriamine), and [Pd(Et4dien)Cl]+ (Et4dien = 1,1,7,7-tetraethyldiethylenetriamine), with unsaturated N-heterocycles such as 3-amino-4-iodo-pyrazole (pzI), 5-amino-4-bromo-3-methyl-pyrazole (pzBr), 1,2,4-triazole, pyrazole, pyrazine, and imidazole were investigated in aqueous 0.10 M NaClO4 in the presence of 10 mM NaCl using variable-temperature stopped-flow spectrophotometry. The second-order rate constants k2 indicate that the reactivity of the Pd(II) complexes decrease in the order [Pd(terpy)Cl]+ > [Pd(bpma)Cl]+ > [Pd(dien)Cl]+ > [Pd(Me4dien)Cl]+ > [Pd(Et4dien)Cl]+. The most reactive nucleophile of the heterocycles is pyrazine, while the slowest reactivity is with pyrazole. Activation parameters were determined for all reactions and negative entropies of activation, ΔS≠, supporting an associative mode of substitution. The reactions between [Pd(bpma)Cl]+ and 1,2,4-triazole, pzI, and pzBr were also investigated by 1H NMR to define the manner of coordination. These results could be useful for better explanation of structure-reactivity relationships of Pd(II) complexes as well as for the prediction of potential targets of Pd(II) complexes toward common N-heterocycles, constituents of biomolecules and different N-bonding pharmaceutical agents.
Lewis base adducts of diisobutylaluminum azide: Synthesis and thermal stability
Creators: name: Bennae, Kenneth T.
name: Powell, Douglas R.
name: Wehmschulte, Rudolf J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Cancer
subject: Developmental Biology
subject: Information and Computing Sciences
subject: Chemistry
subject: Pharmacology
subject: Molecular Biology
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: Diisobutylaluminumazide was prepared from the reaction of diisobutylaluminumhydride with trimethylsilylazide, and it was reacted with five different Lewis bases. The monodentate ligands p-dimethylaminopyridine (DMAP) and the two N-heterocyclic carbenes IMes and IDipp afforded the expected adducts L·Al(i-Bu)2N3 in good yields. Reaction with the bidentate diimine (MesN=CH)2 did not stop at the adduct stage, but continued to form the iminoamide compound {MesNCH2C(i-Bu)NMes}Al(i-Bu)N3 through formal Al-i-Bu addition to one of the N-C double bonds followed by i-Bu migration. The terdentate pincer ligand 2,6-bis(diethylaminomethyl)pyridine induces azide transfer and formation of the ionic compound [2,6-(Et2NCH2)C5H3NAl(i-Bu)2][i-Bu2Al(N3)2]. The compounds are thermally stable to at least 110 °C but decompose either into their precursors or into a mixture of unidentified products. All new compounds were characterized by 1H and 13C{1H} spectroscopy, IR spectroscopy and the iminoamide compound {MesNCH2C(i-Bu)NMes}Al(i-Bu)N3 was also analyzed by single crystal X-ray diffraction.
ABO phenotype protected reproduction as it is based on specific fucosylations.
Creators: name: Arend, Peter
Publisher: name: figshare
Year: 2016
Subjects: subject: Hematology
subject: Medicine
subject: Biochemistry
subject: Cancer
subject: Biological Techniques
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Chemistry
subject: Molecular Biology
subject: Stem Cells
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Anatomy

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or Bombay blood type, which, based on the history of his own family, the Darwin/Wedgewood Dynasty, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the Bombay type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear, via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins, to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. Thus, when antibody-dependent cellular cytotoxicity can be increased 50-fold simply by removing the single fucose residue from the Fc glycan, in Bombay type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
Variation in crystalline architectures through supramolecular interactions in copper(II) complexes with tridentate N2O donor Schiff bases
Creators: name: Jana, Subrata
name: Partha Pratim Jana
name: Shouvik Chattopadhyay
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Chemistry
Earth and Environmental Sciences
Molecular Biology
Cell Biology
Physics
Biochemistry
Biophysics

description: Three copper(II) complexes, [Cu(L1)(H2O)(ClO4)]⋅0.5H2O (1), [Cu(L2)(H2O)(ClO4)]⋅0.5H2O (2) and [Cu(L2)(NCNC(OCH3)NH2)]ClO4 (3), where HL1 = 4-bromo-2-(-(quinolin-8-ylimino)methyl)phenol and HL2 = 1-(-(quinolin-8-ylimino)methyl)naphthalen-2-ol, have been prepared and characterized by elemental analysis, IR, UV-Vis and fluorescence spectroscopy and single-crystal X-ray diffraction studies. The copper(II) centers assume five-coordinate square pyramidal geometries in 1 and 2, whereas square planar copper(II) is present in 3. A methanol molecule has been inserted in the pendant end of the ligated dicyanamide in 3. Various supramolecular architectures are formed by hydrogen bonding, π⋅⋅⋅π, C–H⋅⋅⋅π and lp⋅⋅⋅π interactions.