cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection
Creators: name: Feger, Bryan J.
name: Bowles, Dawn E.
name: Kidane, Yared H.
name: Thompson, J. Will
name: Foster, Matthew W.
name: Shibata, Yoichiro
name: Mishra, Rajashree
name: Moseley, M. Arthur
name: Carnell, Lisa S.
name: Dubois, Laura G.
name: Kommaddi, Reddy P.
name: Shenoy, Sudha K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: On Earth, biological systems have evolved in response to environmental stressors, interactions dictated by physical forces that include gravity. The absence of gravity is an extreme stressor and the impact of its absence on biological systems is ill-defined. Astronauts who have spent extended time under conditions of minimal gravity (microgravity) experience an array of biological alterations, including perturbations in cardiovascular function. We hypothesized that physiological perturbations in cardiac function in microgravity may be a consequence of alterations in molecular and organellar dynamics within the cellular milieu of cardiomyocytes. We used a combination of mass spectrometry-based approaches to compare the relative abundance and turnover rates of 848 and 196 proteins, respectively, in rat neonatal cardiomyocytes exposed to simulated microgravity or normal gravity. Gene functional enrichment analysis of these data suggested that the protein content and function of the mitochondria, ribosomes, and endoplasmic reticulum were differentially modulated in microgravity. We confirmed experimentally that in microgravity protein synthesis was decreased while apoptosis, cell viability, and protein degradation were largely unaffected. These data support our conclusion that in microgravity cardiomyocytes attempt to maintain mitochondrial homeostasis at the expense of protein synthesis. The overall response to this stress may culminate in cardiac muscle atrophy.
Synthesis of Novel 1,4-Disubstituted Piperazines and Evaluation of Their Antibacterial Activities
Creators: name: Shroff, S.
name: Mishra, S. K.
name: Mohanta, P. P.
name: Baitharu, I.
name: Behera, A. K.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Synthesis of Novel 1,4-Disubstituted Piperazines and Evaluation of Their Antibacterial Activities
On the Placement Delivery Array Design in Centralized Coded Caching Scheme
Creators: name: Yan, Qifa
name: Cheng, Minquan
name: Tang, Xiaohu
name: Chen, Qingchun
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: Caching is a promising solution to satisfy the ever increasing demands for the multi-media traffics. In caching networks, coded caching is a recently proposed technique that achieves significant performance gains over the uncoded caching schemes. However, to implement the coded caching schemes, each file has to be split into $F$ packets, which usually increases exponentially with the number of users $K$. Thus, designing caching schemes that decrease the order of $F$ is meaningful for practical implementations. In this paper, by reviewing the Ali-Niesen caching scheme, the placement delivery array (PDA) design problem is firstly formulated to characterize the placement issue and the delivery issue with a single array. Moreover, we show that, through designing appropriate PDA, new centralized coded caching schemes can be discovered. Secondly, it is shown that the Ali-Niesen scheme corresponds to a special class of PDA, which realizes the best coding gain with the least $F$. Thirdly, we present a new construction of PDA for the centralized caching system, wherein the cache size of each user $M$ (identical cache size is assumed at all users) and the number of files $N$ satisfies $M/N=1/q$ or ${(q-1)}/{q}$ ($q$ is an integer such that $q\geq 2$). The new construction can decrease the required $F$ from the order $O\left(e^{K\cdot\left(\frac{M}{N}\ln \frac{N}{M} +(1-\frac{M}{N})\ln \frac{N}{N-M}\right)}\right)$ of Ali-Niesen scheme to $O\left(e^{K\cdot\frac{M}{N}\ln \frac{N}{M}}\right)$ or $O\left(e^{K\cdot(1-\frac{M}{N})\ln\frac{N}{N-M}}\right)$ respectively, while the coding gain loss is only $1$.
description: 21 pages, 2 figures
Die Reichweite der Gewalt der Patriarchen und der Ostkirchen im allgemeinen über die Gläubigen ihres Ritus
Creators: name: Rezac, Giovanni
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 5 Nr. 10 (1969): Concilium: Internationale Zeitschrift für Theologie, Band 5, Heft 10
Absorption Measure Distribution in Mrk 509
Creators: name: Adhikari, T. P.
name: Różańska, A.
name: Sobolewska, M.
name: Czerny, B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In this paper we model the observed absorption measure distribution (AMD) in Mrk 509, which spans three orders of magnitude in ionization level with a single-zone absorber in pressure equilibrium. AMD is usually constructed from observations of narrow absorption lines in radio-quiet active galaxies with warm absorbers. We study the properties of the warm absorber in Mrk~509 using recently published broad-band spectral energy distribution observed with different instruments. This spectrum is an input in radiative transfer computations with full photoionisation treatment using {\sc titan} code. We show that the simplest way to fully reproduce the shape of AMD is to assume that the warm absorber is a single zone under constant total pressure. With this assumption we found theoretical AMD which matches the observed one determined on the basis of 600 ks RGS XMM-Newton spectrum of Mrk~509. The softness of the source spectrum and the important role of the free-free emission breaks the usual degeneracy in the ionization state calculations, and the explicit dependence of the depths of AMD dips on density open a new path to density diagnostic for the warm absorber. In Mrk 509 the implied density is of the order of $10^8$ cm$^{-3}$.
description: 9 pages, 10 figures, Accepted for publication in ApJ
The Use of MnCoFe2O4@GT@Cu Magnetic Nanoparticles in the Synthesis of Benzopyrans
Creators: name: Mobinikhaledi, Akbar
name: Ahadi, Najmieh
name: Haseli, Mohammad
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The Use of MnCoFe2O4@GT@Cu Magnetic Nanoparticles in the Synthesis of Benzopyrans
Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs
Creators: name: Wu, Yaxu
name: Li, Feng
name: Murphy, Christopher M.
name: Cheng, Liang
name: Hu, Jianming
name: Su, Lishan
name: Reszka-Blanco, Natalia J.
name: Chi, Liqun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Chronic Hepatitis B Virus (HBV) infection is generally not curable with current anti-viral drugs. Virus rebounds after stopping treatment from the stable HBV covalently-closed-circular DNA (cccDNA). The development of drugs that directly target cccDNA is hampered by the lack of robust HBV cccDNA models. We report here a novel HBV cccDNA technology that will meet the need. We engineered a minicircle HBV cccDNA with a Gaussia Luciferase reporter (mcHBV-GLuc cccDNA), which serves as a surrogate to measure cccDNA activity. The mcHBV-GLuc cccDNA was easily produced in bacteria, and it formed minichromosomes as HBV cccDNA episome DNA does when it was transfected into human hepatocytes. Compared to non-HBV minicircle plasmids, mcHBV-GLuc cccDNA showed persistent HBV-GLuc activity and HBx-dependent gene expression. Importantly, the mcHBV-GLuc cccDNA showed resistance to interferons (IFN) treatment, indicating its unique similarity to HBV cccDNA that is usually resistant to long-term IFN treatment in chronic HBV patients. Most importantly, GLuc illuminates cccDNA as a surrogate of cccDNA activity, providing a very sensitive and quick method to detect trace amount of cccDNA. The mcHBV-GLuc cccDNA model is independent of HBV infection, and will be valuable for investigating HBV cccDNA biology and for developing cccDNA-targeting drugs.
กระบวนทัศน์การสร้างการรับรู้การปฏิรูประบบบริหารราชการภายใต้ยุทธศาสตร์ชาติ 20 ปี ของสำนักงานศึกษาธิการจังหวัดกรุงเทพมหานคร
Creators: name: พรธิดา ไชยโย
Publisher: name: มหาวิทยาลัยสุโขทัยธรรมาธิราช
Year: 2564
Subjects: กระบวนทัศน์
การสร้างการรับรู้
การปฏิรูประบบบริหารราชการ
ยุทธศาสตร์ชาติ 20 ปี

description: วารสารวิชาการ วิจัย และนวัตกรรม มสธ. (มนุษยศาสตร์และสังคมศาสตร์), 1, 2, 30-48
Selenicereus atropilosus Kimnach 1978
Creators: name: Korotkova, Nadja
name: Borsch, Thomas
name: Arias, Salvador
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Cactaceae
Selenicereus
Selenicereus atropilosus

description: 5.3. Selenicereus atropilosus Kimnach (1978: 270)
 Type:— MEXICO. Jalisco: on road from Mascota to Puerto Vallarta, 3 miles past turnoff to San Sebastian, ca. 870 m, 8 February 1970, Boutin & Kimnach 3190 (holotype HNT-1267!).
description: Published as part of Korotkova, Nadja, Borsch, Thomas & Arias, Salvador, 2017, A phylogenetic framework for the Hylocereeae (Cactaceae) and implications for the circumscription of the genera, pp. 1-46 in Phytotaxa 327 (1) on page 24, DOI: 10.11646/phytotaxa.327.1.1, http://zenodo.org/record/13723813
Feasibility, and validity aspects of Entrustable Professional Activity (EPA)-based assessment in general practice training
Creators: name: Bonnie, Linda Helena Anna
name: Nasori, Mana
name: Visser, Mechteld Renée Maria
name: Kramer, Anneke Wilhelmina Maria
name: van Dijk, Nynke
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Entrustable Professional Activities (EPAs) are developed to support the practical application of competency frameworks in postgraduate medical education (PGME) programmes. EPAs are used for the assessment of the trainees’ competence development, which takes place by means of an entrustment decision, aiming to stimulate learning and independent practice in trainees. In this pilot study, we explore the feasibility and validity of EPA-based assessment in a General Practice (GP) training programme. We used questionnaires to evaluate trainers’ and trainees’ experiences with the use of six EPAs for trainee learning, assessment and independent practice at the Out-of-Hours GP Center. Data were analysed quantitatively and qualitatively. Additionally, we examined the inter-item correlation between scores on EPA-based assessment and competency-based assessment using Spearman’s Rho. EPA-based assessment provided opportunities for giving concrete feedback and substantiating competency-based assessment. No consistent correlation between EPA-based assessment and competency-based assessment could be detected. Only later in the course of the training programme a correlation was found between the EPA scores and the degree of independence of trainees. Results of this pilot study confirm the theories behind EPAs, as well as earlier research on EPAs in the workplace regarding trainee learning, assessment and independent practice. An important limitation of this study was the COVID-19 pandemic, as it influenced the results through reduced inclusion and follow-up, and through the impact on the workplace and trainee learning possibilities. Further research is needed to determine how EPAs support independent practice of trainees, as well as the assessment of trainee competency development.
Can very massive Population III stars produce a super-collapsar?
Creators: name: Yoon, Sung-Chul
name: Kang, Jisu
name: Kozyreva, Alexandra
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: A fraction of the first generation of stars in the early Universe may be very massive ($\gtrsim 300~\mathrm{M_\odot}$) as they form in metal-free environments. Formation of black holes from these stars can be accompanied by supermassive collapsars to produce long gamma-ray bursts of a unique type having a very high total energy ($\sim 10^{54}~\mathrm{erg}$) as recently suggested by several authors. We present new stellar evolution models of very massive Population III stars including the effect of rotation to provide theoretical constraints on super-collapsar progenitors. We find that the angular momentum condition for super-collapsar can be fulfilled if magnetic torques are ignored, in which case Eddington-Sweet circulations play the dominant role for the transport of angular momentum. We further find that the initial mass range for super-collapsar progenitors would be limited to $300~\mathrm{M_\odot} \lesssim M \lesssim 700~\mathrm{M_\odot}$. However, all of our very massive star models of this mass range end their lives as red supergiants rather than blue supergiants, in good agreement with most of the previous studies. The predicted final fate of these stars is either a jet-powered type IIP supernova or an ultra-long, relatively faint gamma-ray transient, depending on the initial amount of angular momentum.
description: 14 pages, 4 figures, 1 table
MiR-142-3p is a RANKL-dependent inducer of cell death in osteoclasts
Creators: name: Naqvi, Afsar Raza
name: Nares, Salvador
name: Guilfoyle, Katherine
name: Fordham, Jezrom B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: MicroRNA are small, non-coding, single-stranded RNAs that are estimated to regulate ~60% of the human genome. MiRNA profiling of monocyte-to-osteoclast differentiation identified miR-142-3p as a miRNA that is significantly, differentially expressed throughout osteoclastogenesis. Enforced expression of miR-142-3p via transient transfection with miR-142-3p mimic inhibited cell-to-cell contact and fusion, decreased protein kinase C alpha expression, and ultimately reduced cell viability. miR-142-3p was also identified as significantly differentially expressed during monocyte-to-macrophage differentiation and overexpression of miR-142-3p prevented their conversion to osteoclasts. Furthermore, the inhibitory effect of miR-142-3p on osteoclastogenesis extended to the conversion of a third osteoclast precursor cell type- dendritic cells. These results demonstrate miR-142-3p to be a negative regulator of osteoclastogenesis from the 3 main precursor cell types: monocytes, macrophages and dendritic cells. Importantly, decreased survival was dependent upon both miR-142-3p expression and RANK-signaling, with no harmful effects detected in the absence of this combination. As such, miR-142-3p represents a novel target for the selective removal of osteoclasts by targeting of osteoclastogenic pathways.
On the Rigidity of Sparse Random Graphs
Creators: name: Linial, Nati
name: Mosheiff, Jonathan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: Discrete Mathematics (cs.DM)
subject: Probability (math.PR)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: A graph with a trivial automorphism group is said to be rigid. Wright proved that for $\frac{\log n}{n}+ω(\frac 1n)\leq p\leq \frac 12$ a random graph $G\in G(n,p)$ is rigid whp. It is not hard to see that this lower bound is sharp and for $p
description: 17 pages
แนวทางเพิ่มประสิทธิภาพการจัดเก็บรายได้ของเทศบาลตำคลองวาฬ อำเภอเมือง จังหวัดประจวบคีรีขันธ์
Creators: name: ชัย แช่มช้อย
Publisher: name: มหาวิทยาลัยสุโขทัยธรรมาธิราช
Year: 2564
Subjects: แนวทางการเพิ่มประสิทธิภาพ
การจัดเก็บรายได้
เทศบาลตำบล

description: วารสารวิชาการ วิจัย และนวัตกรรม มสธ. (มนุษยศาสตร์และสังคมศาสตร์), 1, 2, 49-60
การพัฒนาทรัพยากรมนุษย์ของธนาคารยูโอบี
Creators: name: หฤษฎ์ ศรีสมาน
Publisher: name: มหาวิทยาลัยสุโขทัยธรรมาธิราช
Year: 2564
Subjects: การพัฒนาบุคลากร
ทรัพยากรมนุษย์
ธนาคารยูโอบี
การฝึกอบรม

description: วารสารวิชาการ วิจัย และนวัตกรรม มสธ. (มนุษยศาสตร์และสังคมศาสตร์), 1, 2, 61-71
Complaint-driven preferences & trust: patient’s views on consulting GP trainees
Creators: name: de Bever, Sarah
name: van Rhijn, Suzanne C.
name: Kramer, Anneke Wilhelmina Maria
name: Bont, Jettie
name: van Dijk, Nynke
name: Visser, Mechteld Renée Maria
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Work-based learning depends on patients’ consent to have trainees involved in their care. However, patients can refuse trainees, which might lead to the loss of learning experiences. Improved understanding of patients’ views on consulting trainees may provide useful insights to further optimise learning for trainees. We performed a qualitative study with 28 patients in The Netherlands. Participants were recruited from GP practices, and were purposively sampled on (un)willingness to consult GP trainees. In semi-structured interviews patients’ perspectives and willingness to consult a trainee were explored. Transcripts were thematically analysed using an inductive approach. Two themes explained patients’ views on consulting GP trainees: Presenting complaint-driven preferences and Trust in trainees’ capabilities. Patients select their doctor based on complaint-driven preferences and chose trainees if they fulfilled these preferences. For urgent, gender-specific and minor complaints, patients prefer timeliness, gender concordance or availability. Patients with more complex, long-term problems prefer to consult a trusted doctor with whom they have a longitudinal relationship. Through repeated visits and empathic behaviour trainees can become this doctor. Before patients consider consulting a trainee, they need to have trust in the trainee’s capabilities. This trust is related to the basic trust patients have in the education of the trainee, their knowledge about trainees’ capabilities and supervisory arrangements. Patients’ decision to visit a trainee is fluid. Patients will visit a trainee when their complaint-driven preferences are satisfied. Influencing trainees’ fulfilment of these preferences and patients’ trust in trainees can make patients more willing to consult trainees.
Existence of gradient CKV and gradient conformally stationary LRS spacetimes
Creators: name: Koh, Seoktae
name: Sherif, Abbas M
name: Tumurtushaa, Gansukh
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this work, we study the existence of gradient (proper) CKVs in locally rotationally symmetric spacetimes (LRS), those CKVs in the space spanned by the tangent to observers' congruence and the preferred spatial direction, allowing us to provide a (partial) characterization of gradient conformally static (GCSt) LRS solutions. Irrrotational solutions with non-zero spatial twist admit an irrotational timelike gradient conformal Killing vector field and hence are GCSt. In the case that both the vorticity and twist vanish, that is, restricting to the LRS II subclass, we obtain the necessary and sufficient condition for the spacetime to admit a gradient CKV. This is given by a single wave-like PDE, whose solutions are in bijection to the gradient CKVs on the spacetime. We then introduce a characterization of these spacetimes as GCSt using the character of the divergence of the CKV, provided that the metric functions of the spacetimes obey certain inequalities.
description: 15 pages, no figure, moderate modifications of the Introduction and Discussion sections for clarity, additional references provided and discussed, accepted for publication in Eur. Phys. J. C
การศึกษาสมรรถนะในการบริหารจัดการชั้นเรียนของครูโรงเรียนบ้านสวนอุดมวิทยา สังกัดสำนักงานเขตพื้นที่การศึกษาประถมศึกษาชลบุรี เขต 1
Creators: name: พลธาวิน วัชรทรธำรงค์
Publisher: name: มหาวิทยาลัยสุโขทัยธรรมาธิราช
Year: 2564
Subjects: สมรรถนะ
การบริหารจัดการชั้นเรียน
โรงเรียนประถมศึกษา

description: วารสารวิชาการ วิจัย และนวัตกรรม มสธ. (มนุษยศาสตร์และสังคมศาสตร์), 1, 2, 72-79
title: Drüsenstrukturen und Immunzell-Verteilung in Prostatastanzbiopsien analysiert mittels automatischer Bildanalyse sind prognostische Biomarker für ein biochemisches Rezidiv bei Patienten mit Prostatakarzinom
Creators: name: Buchner, Alexander
name: Athelogou, Maria
name: Hessel, Harald
name: Link, Vera
name: Huss, Ralf
name: Kirchner, Thomas
name: Stief, Christian
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung: Die Struktur der Prostatadrüsen und die Zusammensetzung der Immunzellen im tumor microenvironment spielen eine entscheidende Rolle für die Tumorprogression. In dieser Studie wurden die Prostata-Drüsenmuster und die räumliche T-Zell-Verteilung in Biopsien von Prostatakarzinom-(PCa)-Patienten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
Selenicereus validus S. Arias & U. Guzman 1995
Creators: name: Korotkova, Nadja
name: Borsch, Thomas
name: Arias, Salvador
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Cactaceae
Selenicereus
Selenicereus validus

description: 5.31. Selenicereus validus S. Arias & U. Guzmán (1995: 27–28).
 Type:— MEXICO. Michoacán: Mun. Villa Victoria, 7 km south of Villa Victoria, 600 m, 19 October 1987, Sánchez-Mejorada et al. 4254 (holotype MEXU-1304620!).
description: Published as part of Korotkova, Nadja, Borsch, Thomas & Arias, Salvador, 2017, A phylogenetic framework for the Hylocereeae (Cactaceae) and implications for the circumscription of the genera, pp. 1-46 in Phytotaxa 327 (1) on page 30, DOI: 10.11646/phytotaxa.327.1.1, http://zenodo.org/record/13723813
title: Eingeschränkter diagnostischer und therapeutischer Zusatznutzen der Bildgebung der unteren Extremität bei der Ganzkörper-68Ga-PSMA PET/CT
Creators: name: Stolzenbach, Franziska
name: Maurer, Tobias
name: Budäus, Lars
name: Steuber, Thomas
name: Graefen, Markus
name: Sauer, Markus
name: Kobayashi, Yuske
name: Apostolova, Ivalya
name: Berliner, Christoph
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die PSMA-PET/CT wird zunehmend in der Diagnostik bei Prostatakrebspatienten in verschiedenen Erkrankungsstadien eingesetzt. In der vorliegenden Arbeit untersuchten wir den diagnostischen und therapeutischen Zusatznutzen der Bildgebung der unteren Extremität im Rahmen der Ganzkörper-68Ga-PSMA[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
title: Idealer Zeitpunkt der Dauerkatheterentfernung nach Roboter-assistierter radikaler Prostatektomie – eine prospektive Studie zwischen Dauerkatheterentfernung am 4. und 7. postoperativen Tag an 425 konsekutiven Patienten
Creators: name: Lenart, Sebastian
name: Berger, Ingrid
name: Böhler, Judith
name: Böhm, Reinhard
name: Hartig, Nikolaus
name: Koller, Daniel
name: Lamche, Michael
name: Wayand, Claudia
name: Ponholzer, Anton
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einführung: Der Zeitpunkt der Dauerkatheterentfernung nach einer roboter assistierten radikalen Prostatektomie (RARP) basiert auf empirischen Beobachtungen und ist von abteilungsinternen Präferenzen abhängig. Einerseits soll sowohl eine suffiziente Anastomose gewährleistet sein andererseits[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
Supernova Feedback and the Hot Gas Filling Fraction of the Interstellar Medium
Creators: name: Li, Miao
name: Ostriker, Jeremiah P.
name: Cen, Renyue
name: Bryan, Greg L.
name: Naab, Thorsten
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Supernovae (SN), the most energetic stellar feedback mechanism, are crucial for regulating the interstellar medium (ISM) and launching galactic winds. We explore how supernova remnants (SNRs) create a multiphase medium by performing 3D hydrodynamical simulations at various SN rates, $S$, and ISM average densities, $\bar{n}$. The evolution of a SNR in a self-consistently generated three-phase ISM is qualitatively different from that in a uniform or a two-phase warm/cold medium. By travelling faster and further in the low-density hot phase, the domain of a SNR increases by $>10^{2.5}$. Varying $\bar{n}$ and $S$, we find that a steady state can only be achieved when the hot gas volume fraction $f_{\rm{V,hot}}\lesssim 0.6 \pm 0.1 $. Above that level, overlapping SNRs render connecting topology of the hot gas, and the ISM is subjected to thermal runaway. Photoelectric heating (PEH) has a surprisingly strong impact on $f_{\rm{V,hot}}$. For $\bar{n}\gtrsim 3 \cm-3 $, a reasonable PEH rate is able to suppress the thermal runaway. Overall, we determine the critical SN rate for the onset of thermal runaway to be $S_{\rm{crit}} = 200 (\bar{n}/1\cm-3)^k (E_{\rm{SN}}/10^{51}\erg)^{-1} \kpc^{-3} \myr-1$, where $k = (1.2,2.7)$ for $\bar{n} \leq 1$ and $> 1\cm-3 $, respectively. We present a fitting formula of the ISM pressure $P(\bar{n}$, $S$), which can be used as an effective equation of state in cosmological simulations. Despite the 5 orders of magnitude span of $(\bar{n},S)$, the average Mach number varies little: $\mathcal{M} \approx \ 0.5\pm 0.2, \ 1.2\pm 0.3,\ 2.3\pm 0.9$ for the hot, warm and cold phases, respectively.
description: 57 pages, 16 figures, 3 tables. ApJ accepted
Complaint-driven preferences & trust: patient’s views on consulting GP trainees
Creators: name: de Bever, Sarah
name: van Rhijn, Suzanne C.
name: Kramer, Anneke W.M.
name: Bont, Jettie
name: van Dijk, Nynke
name: Visser, Mechteld R.M.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Work-based learning depends on patients’ consent to have trainees involved in their care. However, patients can refuse trainees, which might lead to the loss of learning experiences. Improved understanding of patients’ views on consulting trainees may provide useful insights to further optimise learning for trainees. We performed a qualitative study with 28 patients in The Netherlands. Participants were recruited from GP practices, and were purposively sampled on (un)willingness to consult GP trainees. In semi-structured interviews patients’ perspectives and willingness to consult a trainee were explored. Transcripts were thematically analysed using an inductive approach. Two themes explained patients’ views on consulting GP trainees: Presenting complaint-driven preferences and Trust in trainees’ capabilities. Patients select their doctor based on complaint-driven preferences and chose trainees if they fulfilled these preferences. For urgent, gender-specific and minor complaints, patients prefer timeliness, gender concordance or availability. Patients with more complex, long-term problems prefer to consult a trusted doctor with whom they have a longitudinal relationship. Through repeated visits and empathic behaviour trainees can become this doctor. Before patients consider consulting a trainee, they need to have trust in the trainee’s capabilities. This trust is related to the basic trust patients have in the education of the trainee, their knowledge about trainees’ capabilities and supervisory arrangements. Patients’ decision to visit a trainee is fluid. Patients will visit a trainee when their complaint-driven preferences are satisfied. Influencing trainees’ fulfilment of these preferences and patients’ trust in trainees can make patients more willing to consult trainees.
title: Knochenspezifische Biomarker im Serum nach Behandlung mit Radium 223 bei Patienten mit kastrationsresistentem Prostatakarzinom und Knochenmetastasen
Creators: name: Maj-Hes, Agnes
name: Sevcenco, Sabrina
name: Eredics, Klaus
name: Kramer, Gero
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: In Prostatakarzinommodellen induzierte Radium-223 DNA Doppelstrangbrüche sowohl in Tumorzellen, als auch in Osteoklasten und Osteoblasten und stabilisierte damit die Knochenmikroumgebung von Knochenmetastasen. In dieser Studie wurde der Effekt von Radium-223 auf diverse Biomarker des[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
Non-strict plurisubharmonicity of energy on Teichmüller space
Creators: name: Tošić, Ognjen
Publisher: name: arXiv
Year: 2023
Subjects: subject: Complex Variables (math.CV)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C07, 53C43

description: For an irreducible representation $ρ:π_1(Σ_g)\to\mathrm{GL}(n,\mathbb{C})$ there is an energy functional $\mathrm{E}_ρ:\mathcal{T}_g\to\mathbb{R}$, defined on Teichmüller space by taking the energy of the associated equivariant harmonic map into the symmetric space $\mathrm{GL}(n,\mathbb{C})/\mathrm{U}(n)$. It follows from a result of Toledo that $\mathrm{E}_ρ$ is plurisubharmonic, i.e. its Levi form is positive semi-definite. We study the kernel of this Levi form, and relate it to the $\mathbb{C}^*$ action on the moduli space of Higgs bundles. We also show that the points in $\mathcal{T}_g$ where strict plurisubharmonicity fails (i.e. this kernel is non-zero) are critical points of the Hitchin fibration. When $n\geq 2$ and $g\geq 3$, we show that for a generic choice $(S,ρ)$, the map $\mathrm{E}_ρ$ is strictly plurisubharmonic. We also describe the kernel of the Levi form for $n=1$.
description: 29 pages, 0 figures
Rechtstheologische Erwägungen zur Grundstruktur einer Lex Fundamentalis Ecclesiae
Creators: name: Dombois, Hans
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 5 Nr. 10 (1969): Concilium: Internationale Zeitschrift für Theologie, Band 5, Heft 10
The First U.S. Naval Observatory Robotic Astrometric Telescope Catalog (URAT1)
Creators: name: Zacharias, Norbert
name: Finch, Charlie
name: Subasavage, John
name: Bredthauer, Greg
name: Crockett, Chris
name: DiVittorio, Mike
name: Ferguson, Erik
name: Harris, Fred
name: Harris, Hugh
name: Henden, Arne
name: Kilian, Chris
name: Munn, Jeff
name: Rafferty, Ted
name: Rhodes, Al
name: Schultheiss, Mike
name: Tilleman, Trudy
name: Wieder, Gary
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: URAT1 is an observational, astrometric catalog covering most of the Dec >= -15 deg area and a magnitude range of about R = 3 to 18.5. Accurate positions (typically 10 to 30 mas standard error) are given for over 228 million objects at a mean epoch around 2013.5. For the over 188 million objects matched with the 2MASS point source catalog proper motions (typically 5 to 7 mas/yr std. errors) are provided. These data are supplemented by 2MASS and APASS photometry. Observations, reductions and catalog construction are described together with results from external data verifications. The catalog data are served by CDS, Starsbourg (I/329). There is no DVD release.
description: accepted by AJ, 21 pages, 17 figures, 5 tables
Lifetime of anthropogenic aerosol perturbations on clouds seen from geostationary SEVIRI satellite data
Creators: name: Rahu, Jorma
name: Toll, Velle
Publisher: name: University of Tartu, Institute of Physics
Year: 2023
Subjects: Aerosol-cloud interactions
Aerosols
SEVIRI
Climate change
Geostationary satellite
Climate forcing

description: The impacts of anthropogenic aerosols on clouds are the most uncertain drivers of anthropogenic climate forcing. Ship-track-like strong anthropogenic cloud perturbations can help reduce these uncertainties. Using geostationary SEVIRI satellite data, we show that strong cloud perturbations downwind of isolated continental anthropogenic aerosol sources can live for multiple days. This item includes the full data-set collected and analysed in the research.
Kimnachia S. Arias & N. Korotkova 2017, gen. nov.
Creators: name: Korotkova, Nadja
name: Borsch, Thomas
name: Arias, Salvador
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Cactaceae
Kimnachia

description: Kimnachia S. Arias & N. Korotkova gen. nov.
 Type:— Kimnachia ramulosa (Salm-Dyck) S. Arias & N. Korotkova, comb. nov.
 Diagnosis: —Plants shrubby with pendent stems, differentiated into primary and secondary stems (dimorphic), primary stems terete, secondary stems flattened and broadened in the apical part, margins of flattened stem segments crenate or obtusely serrate, stems often suffused purple, especially when exposed to sunlight; areoles inconspicuous, lacking spines. Flowers actinomorphic, 1–2 per areole, 7–12 mm long and for up to 15 mm in diameter, pericarpel with small scales, floral tube inconspicuous, ca. 2–4 mm long, green to reddish brown, perianth whitish/yellowish. Fruit globose to ovoid, 4-8 mm in diameter, whitish, pulp whitish.
 Accepted species: —1 (2 infraspecific taxa).
 Etymology: —We name this new genus after our dear colleague Myron Kimnach. He is an outstanding expert on the epiphytic cacti, and in particular on the Hylocereeae and his publications were a significant contribution to our knowledge on this group of plants. It is therefore our great pleasure to honour his works by dedicating this genus to him.
description: Published as part of Korotkova, Nadja, Borsch, Thomas & Arias, Salvador, 2017, A phylogenetic framework for the Hylocereeae (Cactaceae) and implications for the circumscription of the genera, pp. 1-46 in Phytotaxa 327 (1) on page 30, DOI: 10.11646/phytotaxa.327.1.1, http://zenodo.org/record/13723813
Enhancing Quantum Support Vector Machines through Variational Kernel Training
Creators: name: Innan, Nouhaila
name: Khan, Muhammad Al-Zafar
name: Panda, Biswaranjan
name: Bennai, Mohamed
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Machine Learning (cs.LG)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Quantum machine learning (QML) has witnessed immense progress recently, with quantum support vector machines (QSVMs) emerging as a promising model. This paper focuses on the two existing QSVM methods: quantum kernel SVM (QK-SVM) and quantum variational SVM (QV-SVM). While both have yielded impressive results, we present a novel approach that synergizes the strengths of QK-SVM and QV-SVM to enhance accuracy. Our proposed model, quantum variational kernel SVM (QVK-SVM), leverages the quantum kernel and quantum variational algorithm. We conducted extensive experiments on the Iris dataset and observed that QVK-SVM outperforms both existing models in terms of accuracy, loss, and confusion matrix indicators. Our results demonstrate that QVK-SVM holds tremendous potential as a reliable and transformative tool for QML applications. Hence, we recommend its adoption in future QML research endeavors.
description: 15 pages, 13 figures, 1 table
title: Low dose rate Brachytherapie ist der radikalen Prostatektomie nicht unterlegen in der Therapie des lokalisierten low-risk Prostatakarzinoms
Creators: name: Ladurner, Michael
name: Sztankay, Balázs
name: Horninger, Wolfgang
name: Bektic, Jasmin
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung: Bei der low dose rate (LDR)-Brachytherapie (BT) der Prostata verfügt man bereits über eine langjährige Erfahrung bei der Therapie des low-risk Prostatakarzinoms (PCa). Trotzdem wurde diese Therapie noch nie direkt mit der radikalen Prostatektomie (RPE) verglichen. Daher[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
Der soziale Dynamismus der der Kirche als Gemeinschaft eigen ist, und seine Rückwirkung auf den notwendigen Dynamismus des kanonischen Rechts
Creators: name: Neumann, Johannes
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 5 Nr. 10 (1969): Concilium: Internationale Zeitschrift für Theologie, Band 5, Heft 10
title: Hereditäres Prostatakarzinom – zwei Fallberichte in Diskussion
Creators: name: Schörghofer, David
name: Uyanik, Gökhan
name: Rötzer, Katharina
name: Plas, Eugen
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Prostatakarzinom stellt die häufigste Krebserkrankung und die dritthäufigste Krebstodesursache bei Männern in Europa dar. Nichtsdestotrotz ist der Einfluss von genetischen Faktoren bis heute nicht eindeutig geklärt. Es wird geschätzt, dass in etwa 10% erbliche Ursachen [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
Supplementary text, figures and tables from Dogs take into account the actions of a human partner in a cooperative task from Dogs take into account the actions of a human partner in a cooperative task
Creators: name: Martínez, Mayte
name: Robinson, Lauren M.
name: Brosnan, Sarah F.
name: Range, Friederike
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The document contains detailed description of set-ups, experimental procedures, statistical analyses and tables showing the models' results
Vorwort
Creators: name: Huizing, Piet
name: Urresti, Jimenes Teodoro
name: Edelby, Neophytos
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 5 Nr. 10 (1969): Concilium: Internationale Zeitschrift für Theologie, Band 5, Heft 10
title: Assoziation der super-extendierten Lymphadenektomie bei der radikalen Zystektomie mit perioperativen Komplikationen und Rehospitalisierung
Creators: name: D'Andrea, David
name: Abufaraj, Mohammad
name: Korn, Stephan
name: Soria, Francesco
name: Gust, Kilian
name: Haitel, Andrea
name: Shariat, Shahrokh F.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Ziel: Ziel dieser retrospektiven Analyse von PatientInnen, die eine radikale Zystektomie und Lymphadenektomie zur Behandlung eines Urothelkarzinoms der Blase erhielten, ist es den Einfluss der Lymphadenektomie unterschiedlichen Ausmaßes auf perioperative Komplikationen und Rehospitalisierung aufzuzeigen.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 45. Gemeinsame Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung
Pseudorhipsalis lankesteri Barthlott 1991
Creators: name: Korotkova, Nadja
name: Borsch, Thomas
name: Arias, Salvador
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Caryophyllales
Cactaceae
Pseudorhipsalis
Pseudorhipsalis lankesteri

description: 7.5. Pseudorhipsalis lankesteri (Kimnach) Barthlott (1991: 90)
 Type:— COSTA RICA. Puntarenas: Valle de El General, ca. 670 m, ca. 1940, Lankester s.n. (holotype HNT-1214!).
description: Published as part of Korotkova, Nadja, Borsch, Thomas & Arias, Salvador, 2017, A phylogenetic framework for the Hylocereeae (Cactaceae) and implications for the circumscription of the genera, pp. 1-46 in Phytotaxa 327 (1) on page 32, DOI: 10.11646/phytotaxa.327.1.1, http://zenodo.org/record/13723813
Myeloid tissue factor does not modulate lung inflammation or permeability during experimental acute lung injury
Creators: name: Ware, Lorraine B.
name: Mackman, Nigel
name: Grove, Brandon S.
name: Clune, Jennifer K.
name: Bastarache, Julie A.
name: Shaver, Ciara M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Tissue factor (TF) is a critical mediator of direct acute lung injury (ALI) with global TF deficiency resulting in increased airspace inflammation, alveolar-capillary permeability, and alveolar hemorrhage after intra-tracheal lipopolysaccharide (LPS). In the lung, TF is expressed diffusely on the lung epithelium and intensely on cells of the myeloid lineage. We recently reported that TF on the lung epithelium, but not on myeloid cells, was the major source of TF during intra-tracheal LPS-induced ALI. Because of a growing body of literature demonstrating important pathophysiologic differences between ALI caused by different etiologies, we hypothesized that TF on myeloid cells may have distinct contributions to airspace inflammation and permeability between direct and indirect causes of ALI. To test this, we compared mice lacking TF on myeloid cells (TF∆mye, LysM.Cre+/−TFflox/flox) to littermate controls during direct (bacterial pneumonia, ventilator-induced ALI, bleomycin-induced ALI) and indirect ALI (systemic LPS, cecal ligation and puncture). ALI was quantified by weight loss, bronchoalveolar lavage (BAL) inflammatory cell number, cytokine concentration, protein concentration, and BAL procoagulant activity. There was no significant contribution of TF on myeloid cells in multiple models of experimental ALI, leading to the conclusion that TF in myeloid cells is not a major contributor to experimental ALI.
Rehabilitating Homeless: Dataset and Key Insights
Creators: name: Bykova, Anna
name: Filippov, Nikolay
name: Yamshchikov, Ivan P.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (cs.LG)
subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: This paper presents a large anonymized dataset of homelessness alongside insights into the data-driven rehabilitation of homeless people. The dataset was gathered by a large nonprofit organization working on rehabilitating the homeless for twenty years. This is the first dataset that we know of that contains rich information on thousands of homeless individuals seeking rehabilitation. We show how data analysis can help to make the rehabilitation of homeless people more effective and successful. Thus, we hope this paper alerts the data science community to the problem of homelessness.
description: Dataset, code and appendix to this article are available at https://github.com/LEYADEV/homeless
Arnold diffusion in the planar elliptic restricted three-body problem: mechanism and numerical verification
Creators: name: Capinski, Maciej J.
name: Gidea, Marian
name: de la Llave, Rafael
Publisher: name: arXiv
Year: 2015
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: Primary: 37J25, 37J40, secondary: 70F07, 70F15, 70K44, 34C37

description: We present a diffusion mechanism for time-dependent perturbations of autonomous Hamiltonian systems introduced in [25]. This mechanism is based on shadowing of pseudo-orbits generated by two dynamics: an `outer dynamics', given by homoclinic trajectories to a normally hyperbolic invariant manifold, and an `inner dynamics', given by the restriction to that manifold. On the inner dynamics the only assumption is that it preserves area. Unlike other approaches, [25] does not rely on the KAM theory and/or Aubry-Mather theory to establish the existence of diffusion. Moreover, it does not require to check twist conditions or non-degeneracy conditions near resonances. The conditions are explicit and can be checked by finite precision calculations in concrete systems. As an application, we study the planar elliptic restricted three-body problem. We present a rigorous theorem that shows that if some concrete calculations yield a non zero value, then for any sufficiently small, positive value of the eccentricity of the orbits of the main bodies, there are orbits of the infinitesimal body that exhibit a change of energy that is bigger than some fixed number, which is independent of the eccentricity. We verify numerically these calculations for values of the masses close to that of the Jupiter/Sun system. The numerical calculations are not completely rigorous, because we ignore issues of round-off error and do not estimate the truncations, but they are not delicate at all by the standard of numerical analysis. (Standard tests indicate that we get 7 or 8 figures of accuracy where 1 would be enough). The code of this verifications is available. We hope that some full computer assisted proofs will be obtained in a near future since there are packages (CAPD) designed for problems of this type.
description: 34 pages, 11 figures
Sakralisierung und Säkularisierung in den Kirchen des Ostens
Creators: name: Dalmais, Irénée Henri
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 5 Nr. 8/9 (1969): Concilium: Internationale Zeitschrift für Theologie, Band 5, Heft 8/9
Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1
Creators: name: Li, Wei
name: Xia, Zheng
name: Cooper, Thomas A.
name: Giudice, Jimena
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: The RNA binding protein Celf1 regulates alternative splicing in the nucleus and mRNA stability and translation in the cytoplasm. Celf1 is strongly down-regulated during mouse postnatal heart development. Its re-induction in adults induced severe heart failure and reversion to fetal splicing and gene expression patterns. However, the impact of Celf1 depletion on cardiac transcriptional and posttranscriptional dynamics in neonates has not been addressed. We found that homozygous Celf1 knock-out neonates exhibited cardiac dysfunction not observed in older homozygous animals, although homozygous mice are smaller than wild type littermates throughout development. RNA-sequencing of mRNA from homozygous neonatal hearts identified a network of cell cycle genes significantly up-regulated and down-regulation of ion transport and circadian genes. Cell cycle genes are enriched for Celf1 binding sites supporting a regulatory role in mRNA stability of these transcripts. We also identified a cardiac splicing network coordinated by Celf1 depletion. Target events contain multiple Celf1 binding sites and enrichment in GU-rich motifs. Identification of direct Celf1 targets will advance our knowledge in the mechanisms behind developmental networks regulated by Celf1 and diseases where Celf1 is mis-regulated.