cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Antichain cutsets of strongly connected posets
Creators: name: Foldes, Stephan
name: Woodroofe, Russ
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Rival and Zaguia showed that the antichain cutsets of a finite Boolean lattice are exactly the level sets. We show that a similar characterization of antichain cutsets holds for any strongly connected poset of locally finite height. As a corollary, we get such a characterization for semimodular lattices, supersolvable lattices, Bruhat orders, locally shellable lattices, and many more. We also consider a generalization to strongly connected hypergraphs having finite edges.
description: 12 pages; v2 contains minor fixes for publication
Alamblak Alveopalatals - Dead Portmanteaus
Creators: name: Bruce Jr., Leslie (Ed.)
Publisher: name: Pacific Linguistics
Year: 1975

description: ALAMBLAK ALVEOPALATALS - DEAD PORTMANTEAUS. 91 0. INTRODUCTION 91 1. ALVEOLAR /t/ AND ALVEOPALATAL /s/ 92 2. /d/ AND /j/ 94 3. /n/ AND /ñ/ 96 4. CONCLUSION 97Notes 99Bibliography 102
title: Heat Transfer across the Free Surface of a Thermocapillary Liquid Bridge
Creators: name: Roman`o, F.
name: H. C. Kuhlmann
Publisher: name: Otto von Guericke University Library, Magdeburg, Germany
Year: 2019

description: Technische Mechanik; 39; 1; 72-84; ISSN 2199-9244
description: The heat transfer across the free surface of a millimetric thermocapillary liquid bridge is investigated for twodimensional axisymmetric flows,  computed by Newton�Raphson iteration.   The coupled multiphase flow in thesilicone-oil liquid bridge and in the ambient gas (air) is considered for Marangoni and Prandtl numbers of interestfor typical space experiments.  Based on the space-resolved heat flux of the two-phase flow for a wide range ofparameters, we derive a model for the heat flux in form of Newton�s heat transfer law for a surrogate single phaseflow, in which a space-dependent Biot function is considered.  A parametric study for a 2 cSt silicone-oil liquidbridge is conducted for 150 configurations to derive a reliable fit of the Biot function for a wide range of Reynoldsnumbers and aspect ratios. An explicit form of the parametric fit is provided which takes into account the hot- andcold-wall boundary layers in the liquid.
What Do Buildings Do All Day?
Creators: name: Jones, D'Arcy
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Conceptual Architecture
subject: Paper Architecture
subject: Irreverent Architecture
subject: Subversive Architecture
subject: Critical Practice
subject: Architecture
subject: FOS: Civil engineering

description: Architectural practice is serious stuff. This thesis challenges the conventions that limit creativity by poking fun at architectural sincerity. Non-architectural ways and things inspire contrarian inventions within fictional and nonfiction case studies. The design process itself is questioned. Explorations embrace ordinariness by paying more attention to the everyday. The results describe creative techniques prioritizing logic over expectations, function over aesthetics, and people over form. In a profession where imitation and familiarity are valued more than irreverence, this thesis defines a new model of critical practice that can subversively change architecture from the inside.
Bounded Arithmetic in Free Logic
Creators: name: Yamagata, Yoriyuki
Publisher: name: arXiv
Year: 2012
Subjects: subject: Logic (math.LO)
subject: Logic in Computer Science (cs.LO)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: cs.LO

description: One of the central open questions in bounded arithmetic is whether Buss' hierarchy of theories of bounded arithmetic collapses or not. In this paper, we reformulate Buss' theories using free logic and conjecture that such theories are easier to handle. To show this, we first prove that Buss' theories prove consistencies of induction-free fragments of our theories whose formulae have bounded complexity. Next, we prove that although our theories are based on an apparently weaker logic, we can interpret theories in Buss' hierarchy by our theories using a simple translation. Finally, we investigate finitistic Gödel sentences in our systems in the hope of proving that a theory in a lower level of Buss' hierarchy cannot prove consistency of induction-free fragments of our theories whose formulae have higher complexity.
Professional Stakeholders’ Views of the Family Violence Act 2016 (ACT): Has Law Reform Achieved Its Primary Aims?
Creators: name: Easteal, Patricia
name: Bartels, Lorana
name: Dodd, Shannon
Publisher: name: Monash University
Year: 2023
Subjects: Other law and legal studies not elsewhere classified
Family law

description: The Family Violence Act 2016 (ACT) represents the Australian Capital Territory government’s legislative response to issues of family violence (‘FV’). While the Act aimed to better safeguard those experiencing FV, it is yet to be seen whether those amendments are effective and/or operating as intended. Through interviews with a range of professional stakeholders working at the coalface of FV issues, this paper shows that, while some improvements have been made, there remain issues with the ambiguity of provisions, the scope of the people and abusive behaviours protected under the Act, the lack of police enforcement, information-sharing and inter-agency communication, and adequate resourcing. Suggestions are made for improving the Act and its implementation.
Brain Magnetic Resonance Spectroscopy: Advances and Applications to Chronic Pain in Knee Osteoarthritis
Creators: name: Leech, Samantha
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Magnetic Resonance Spectroscopy
subject: Single Voxel Spectroscopy
subject: Quantification
subject: Brain
subject: Knee
subject: Osteoarthritis
subject: Pain
subject: Engineering--Biomedical
subject: Neuroscience

description: This dissertation investigates advancements in brain proton magnetic resonance spectroscopy (1H-MRS) measures and their application to chronic pain in knee osteoarthritis. 1H-MRS measures proton signals, which can be converted into absolute concentrations using the properties of water, brain tissue, and neurochemicals. These concentrations serve as markers of brain health or dysfunction. Current methods to quantify absolute neurochemical concentrations assume an equal distribution of neurochemicals between white matter (WM) and gray matter (GM), an assumption not thoroughly examined. To address this, I determined the distribution of six neurochemicals between WM and GM to establish correction factors to replace assumptions with calculated values. After validation using an independent dataset, I created an open-source tool to implement the calculated correction factors, improving 1H-MRS accuracy by 30-55%. I used quantitative synthetic imaging to measure water properties — relaxation rates (T1 and T2) and proton density (PD) — in different brain tissues of healthy adults. I assessed the impact of inter-individual differences in T1, T2, and PD on neurochemical concentration measures by comparing concentrations calculated using literature-based constants (as is typically performed) to concentrations calculated using individual measures from quantitative maps. In a young, healthy population, individual measures contributed to subtle yet significant variations in calculated neurochemical concentrations, suggesting that using uniform literature values may not be accurate for every individual. Sensitivity analyses indicated that these inaccuracies are likely greater across a wider age range or in individuals with clinical disorders. Applying 1H-MRS, I identified potential neurochemicals and brain regions associated with chronic pain in knee osteoarthritis to understand the brain’s role in this condition. Knee osteoarthritis is a leading cause of chronic pain, with limited research on the specific neurochemicals and brain regions involved. I compared neurochemical levels and their association with pain measures in four brain regions between patients with knee osteoarthritis and healthy controls as well as longitudinally in patients three months after total knee replacement surgery. I found opposing relationships in brain regions associated with pain's sensory and affective dimensions. This dissertation enhances the accuracy of neurochemical concentration quantification and refines the understanding of the brain's contribution to knee osteoarthritis pain.
Aggregation of rod-like polyelectrolyte chains in the presence of monovalent counterions
Creators: name: Varghese, Anoop
name: Rajesh, R.
name: Vemparala, Satyavani
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Using molecular dynamics simulations, it is demonstrated that monovalent counterions can induce aggregation of similarly charged rod-like polyelectrolyte chains. The critical value of the linear charge density for aggregation is shown to be close to the critical value for the extended-collapsed transition of a single flexible polyelectrolyte chain, and decreases with increasing valency of the counterions. The effective interaction potential between two rod-like polyelectrolyte chains is measured, and is related to the angular distribution of the condensed counterions.
description: 8 pages, 5 figures
ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons
Creators: name: Hirabayashi, Yusuke
name: Kwon, Seok-Kyu
name: Paek, Hunki
name: Pernice, Wolfgang Maximilian
name: Paul, Maëla A.
name: Lee, Jinoh
name: Erfani, Parsa
name: Raczkowski, Ashleigh
name: Petrey, Donald S.
name: Pon, Liza A.
name: Polleux, Franck
Publisher: name: Columbia University
Year: 2017
Subjects: Cell physiology
Molecular neurobiology
Cell organelles
Endoplasmic reticulum

description: Interfaces between organelles are emerging as critical platforms for many biological responses in eukaryotic cells. In yeast, the ERMES complex is an endoplasmic reticulum (ER)-mitochondria tether composed of four proteins, three of which contain a SMP (synaptotagmin-like mitochondrial-lipid binding protein) domain. No functional ortholog for any ERMES protein has been identified in metazoans. Here, we identified PDZD8 as an ER protein present at ER-mitochondria contacts. The SMP domain of PDZD8 is functionally orthologous to the SMP domain found in yeast Mmm1. PDZD8 was necessary for the formation of ER-mitochondria contacts in mammalian cells. In neurons, PDZD8 was required for calcium ion (Ca2+) uptake by mitochondria after synaptically induced Ca2+-release from ER and thereby regulated cytoplasmic Ca2+ dynamics. Thus, PDZD8 represents a critical ER-mitochondria tethering protein in metazoans. We suggest that ER-mitochondria coupling is involved in the regulation of dendritic Ca2+ dynamics in mammalian neurons.
The Energetic Costs of Cellular Computation
Creators: name: Mehta, Pankaj
name: Schwab, David J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: Cells often perform computations in response to environmental cues. A simple example is the classic problem, first considered by Berg and Purcell, of determining the concentration of a chemical ligand in the surrounding media. On general theoretical grounds (Landuer's Principle), it is expected that such computations require cells to consume energy. Here, we explicitly calculate the energetic costs of computing ligand concentration for a simple two-component cellular network that implements a noisy version of the Berg-Purcell strategy. We show that learning about external concentrations necessitates the breaking of detailed balance and consumption of energy, with greater learning requiring more energy. Our calculations suggest that the energetic costs of cellular computation may be an important constraint on networks designed to function in resource poor environments such as the spore germination networks of bacteria.
description: 9 Pages (including Appendix); 4 Figures; v3 corrects even more typos
Academic performance of university students in a transdisciplinary bachelor's degree
Creators: name: Papa, María Fernanda
name: De Castro, María Valeria
name: Becker, Pablo
name: Marcos Martinez, Esperanza
name: Olsina, Luis
Publisher: name: Zenodo
Year: 2018
Subjects: Students' performance
Service sector
Monitoring strategy

description: The Bachelor's degree in Service Science, Management and Engineering is a transdisciplinary proposal that attracts students from

different secondary school modalities, which cause an apparent disparity of knowledge upon entry that would be affecting their academic performance.

Using a monitoring strategy the new students were monitored during their first year of study. As a result, it was possible to characterize

the students' performance according to their modality and to propose types of instruments to improve it according to the detected needs.
Skyrmions from gravitational instantons
Creators: name: Dunajski, Maciej
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Mathematical Physics (math-ph)
subject: Differential Geometry (math.DG)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We propose a construction of Skyrme fields from holonomy of the spin connection of gravitational instantons. The procedure is implemented for Atiyah-Hitchin and Taub-NUT instantons. The skyrmion resulting from the Taub-NUT is given explicitly on the space of orbits of a left translation inside the whole isometry group. The domain of the Taub-NUT skyrmion is a trivial circle bundle over the Poincare disc. The position of the skyrmion depends on the Taub-NUT mass parameter, and its topological charge is equal to two.
description: Major changes: The Atiyah-Hitchin manifold and the corresponding skyrmion discussed in more detail, gauge fixing procedure clarified, earlier errors corrected. Final version, to appear in Proceedings of the Royal Society A
Investigation of Experimental Conditions Impacting the Kinetics of Vapor Phase Combustion in Air Injection-Based Processes for Alberta Bitumen through Experimental and Simulation Modeling
Creators: name: Feizabadi, SeyedEbrahim
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: In Situ Combustion
subject: Kinetics
subject: Oilsands
subject: Heavy Oil Recovery
subject: Athabasca bitumen
subject: Vapor Phase Combustion
subject: Simulation and Numerical Modeling
subject: Experimental Modeling
subject: Thermal Methods
subject: Chemical Reactions
subject: Air Injection
subject: Energy
subject: Engineering
subject: Psychology--Experimental
subject: Engineering--Chemical
subject: Engineering--Petroleum

description: When air is injected into a formation, it results in a series of reactions between a substantial number of different hydrocarbon species and oxygen present in the air. As these reactions occur on a wide temperature range (temperature dependence); thus, the crude oil composition is altered during the life of the process which puts on more complexities (time dependence) in the understanding of the process (chemical changes). Kinetics is the area in the combustion literature that deals with the chemical reactions occurring during the process and many researchers have tried to realize the nature of oxidation reactions to develop a better understanding of this recovery method. To date, despite the significant works presented in the literature, there is still a lack of understanding of the kinetics associated with the combustion reactions representing the compositional changes and heat generation rates. Traditionally, in the majority of the kinetic reaction models, it is believed that oil undergoes Low Temperature Oxidation and pyrolysis reactions before it burns, and coke is the main product which is the source of the fuel for High Temperature Oxidation reactions. However, In Situ Combustion Research Group (ISCRG) at the University of Calgary believes that vapor phase combustion is an important unrecognized parameter in most of kinetic models which have been presented in the literature. Even though some recent publications have considered vapor phase combustion in their kinetic models, there are still inaccuracies associated with the results predicted by these kinetic models [1], [2], [3], [4], [5]. To gain a deeper insight into the vapor phase combustion, a unique specially designed experimental study with the ability to capture the vapor phase combustion was conducted in Ebrahim Feizabadi’s M.Sc. thesis [6]. While this study showed valuable results indicating the existence of the vapor phase combustion, it also resulted in some new questions that must be answered to better understand the vapor phase combustion in air injection-based processes [6]. In this new study which will be discussed in detail in the following sections of this thesis, the effects of the experimental apparatus parameters on the kinetics of vapor phase combustion were investigated.
Scymnus (Pullus) jaculatorius Yu, new species
Creators: name: Yu, Guoyue
name: Montgomery, Michael E.
name: Yao, Defu
Publisher: name: Zenodo
Year: 2000
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Coccinellidae
Scymnus
Scymnus jaculatorius

description: Scymnus (Pullus) jaculatorius Yu, new species (Fig. 18) Description. Male. Length 1.85 mm, width 1.10 mm. Form oval with sides nearly parallel at middle, dorsum moderately convex. Color black, except basal two segments of antennae, apical margin of terminal segment of maxillary palpi, tarsi, and posterior part of abdomen brown. Interocular distance slightly less than 1/2 head width. Innerocular margins arcuate, divergent posteriorly. Frons finely, densely punctate. Antenna 11­ segmented, proportions as illustrated (Fig. 18j). Maxillary palpus terminal segment with arcuate sides, distal side slightly oblique. Pronotum punctation coarser than head. Elytral punctures slightly finer than pronotum, much coarser than head, pubescence arranged in S­form. Prosternal carinae distinctly convergent anteriorly. Postcoxal line of first abdominal sternite arcuate, complete, extending about 2/5 sternite length, enclosed area irregularly punctate, coarser posteriorly, smooth near line. Fifth abdominal sternite hind margin broadly arcuate; sixth sternite apex distinctly emarginate. Genitalia: Sipho (Fig. 18a) relatively slender, basal 2/3 strongly arcuate; siphonal capsule with short outer process, long inner process; simple siphonal apex, without appendix. Tegmen (Fig. 18b, c) characteristic; in ventral aspect, median piece narrowing gradually from base for 5/6 length then sharply to teat­shaped tip; in lateral aspect, median piece thickest at basal 1/3. Lateral lobes of tegmen slightly shorter than median piece, with short setae. Distribution. China (Yunnan). Type Series. Holotype: (Ƌ), Yunnan: Lijiang: Yuelongxueshan (26.8 N, 100.2 E), 30­IV­1997, Yao D. et al. leg. (BAAF). Etymology. The name refers to the shape of the median piece of tegmen in lateral view. Remarks. This species resembles S. (P.) robustibasalis Yu, new species, and S. (Neopullus) ater Kugelann in body size and coloration. It differs from the former by relatively long lateral lobes of tegmen, slender siphonal capsule and overall black dorsal surface. In the latter species, the median piece of tegmen is distinctly shorter than the lateral lobes, and the lateral lobes have long setae. It also resembles Pseudoscymnus tsugae Sasaji and McClure in coloration, but the body of the new species is more slender.
description: Published as part of Yu, Guoyue, Montgomery, Michael E. & Yao, Defu, 2000, Lady Beetles (Coleoptera: Coccinellidae) From Chinese Hemlocks Infested With The Hemlock Woolly Adelgid, Adelges Tsugae Annand (Homoptera: Adelgidae), pp. 154-199 in The Coleopterists Bulletin 54 (2) on pages 181-182, DOI: 10.1649/0010-065X(2000)054[0154:LBCCFC]2.0.CO;2
Unmating of rational maps, sufficient criteria and examples
Creators: name: Meyer, Daniel
Publisher: name: arXiv
Year: 2011
Subjects: subject: Complex Variables (math.CV)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37F10

description: Douady and Hubbard introduced the operation of mating of polynomials. This identifies two filled Julia sets and the dynamics on them via external rays. In many cases one obtains a rational map. Here the opposite question is tackled. Namely we ask when a given (postcritically finite) rational map $f$ arises as a mating. A sufficient condition when this is possible is given. If this condition is satisfied, we present a simple explicit algorithm to unmate the rational map. This means we decompose $f$ into polynomials, that when mated yield $f$. Several examples of unmatings are presented.
description: 35 pages, 8 figures
The Differential Equation in Terms of Jacobsthal and Jacobsthal-Lucas Numbers
Creators: name: Mongkol Tatong
Publisher: name: Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi
Year: 2023
Subjects: differential equations
Jacobsthal number
Jacobsthal-Lucas number

description: Progress in Applied Science and Technology, 13, 1, 1-6
Psychological targeting as an effective approach to digital mass persuasion
Creators: name: Matz, Sandra C.
name: Kosinski, Michal
name: Nave, Gideon
name: Stillwell, David J.
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Persuasion (Psychology)
subject: Mass media--Influence
subject: Advertising media planning
subject: Psychology
subject: FOS: Psychology
subject: Target marketing

description: People are exposed to persuasive communication across many different contexts: Governments, companies, and political parties use persuasive appeals to encourage people to eat healthier, purchase a particular product, or vote for a specific candidate. Laboratory studies show that such persuasive appeals are more effective in influencing behavior when they are tailored to individuals’ unique psychological characteristics. However, the investigation of large-scale psychological persuasion in the real world has been hindered by the questionnaire-based nature of psychological assessment. Recent research, however, shows that people’s psychological characteristics can be accurately predicted from their digital footprints, such as their Facebook Likes or Tweets. Capitalizing on this form of psychological assessment from digital footprints, we test the effects of psychological persuasion on people’s actual behavior in an ecologically valid setting. In three field experiments that reached over 3.5 million individuals with psychologically tailored advertising, we find that matching the content of persuasive appeals to individuals’ psychological characteristics significantly altered their behavior as measured by clicks and purchases. Persuasive appeals that were matched to people’s extraversion or openness-to-experience level resulted in up to 40% more clicks and up to 50% more purchases than their mismatching or unpersonalized counterparts. Our findings suggest that the application of psychological targeting makes it possible to influence the behavior of large groups of people by tailoring persuasive appeals to the psychological needs of the target audiences. We discuss both the potential benefits of this method for helping individuals make better decisions and the potential pitfalls related to manipulation and privacy.
Cold gas accretion by high-velocity clouds and their connection to QSO absorption-line systems
Creators: name: Richter, Philipp
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We combine HI 21cm observations of the Milky Way, M31, and the local galaxy population with QSO absorption-line measurements to geometrically model the three-dimensional distribution of infalling neutral gas clouds (HVCs) in the extended halos of low-redshift galaxies. We demonstrate that the observed distribution of HVCs around the Milky Way and M31 can be modeled by a radial exponential decline of the mean HI volume filling factor in their halos. Our model suggests a characteristic radial extent of HVCs of R_halo=50 kpc, a total HI mass in HVCs of ~10^8 M_sun, and a neutral-gas-accretion rate of ~0.7 M_sun/yr for M31/Milky-Way-type galaxies. Using a Holmberg-like luminosity scaling of the halo size of galaxies we estimate R_halo=110 kpc for the most massive galaxies. The total absorption-cross section of HVCs at z=0 most likely is dominated by galaxies with total HI masses between 10^8.5 and 10^10 M_sun. Our model indicates that the HI disks of galaxies and their surrounding HVC population can account for 30-100 percent of intervening QSO absorption-line systems with log N(HI)>17.5 at z=0. We estimate that the neutral-gas accretion rate density of galaxies at low redshift from infalling HVCs is dM_HI/dt/dV=0.022 M_sun/yr/Mpc^3, which is close to the measured star-formation rate density in the local Universe. HVCs thus may play an important role for the on-going formation and evolution of galaxies.
description: 12 pages, 3 figures, 3 tables; accepted for publication in ApJ
title: Modelling of Heat Transfer and Fluid Flow through a Granular Material and External Wall Barrier
Creators: name: Szymanek, E.
name: A. Tyliszczak
Publisher: name: Otto von Guericke University Library, Magdeburg, Germany
Year: 2019

description: Technische Mechanik; 39; 1; 85-95; ISSN 2199-9244
description: Heat and fluid flow simulations for granular material in wall barriers allow to design them in a way that maximallyreduces the expenditures on utilisation of buildings.  This paper demonstrates the solution to the problem of thepassage of air through the external wall barrier.  It shows how the temperature changes inside the wall barrierswhen the external temperature changes.  Two types of partitions are tested:  single-layer (granular material) andtwo-layer (granular and concrete material). The paper presents comparison of the results of the numerical modeland in-house code with the experimental data.  The numerical model applied is based on the unsteady equationof heat conduction (3D) and the Navier-Stokes equations.  A high-order compact method in combination with theWENO scheme and predictor-corrector method are applied for the spatio-temporal discretisation. The flows of airand heat in the granular layers are modelled using immersed boundary technique, which allows to use Cartesianmeshes for objects with very complex geometric shapes.  The correctness of numerical model applied has beenverified by comparisons with ANSYS Fluent results and experimental data obtained from measurements performedin a laboratory and in-situ.
Murine CD248 and its cytoplasmic domain : characterising a novel tumour and inflammation marker
Creators: name: Juhász, Margit Lai Wun
Publisher: name: University of British Columbia
Year: 2012

description: CD248 is a member of a family of transmembrane glycoproteins containing an N-terminal C-type lectin-like domain. This family includes thrombomodulin and CD93, proteins known to modulate immunity, cell proliferation and homeostasis. CD248 is expressed in perivascular and stromal cells, during embryonic development and post-natally during inflammation and cancer. In the mesenchymal compartment of most normal adult tissues, CD248 expression is not detectable. It is believed that CD248 is involved in cross-talk between endothelial cells and pericytes, thereby playing a role in growth, metastasis and angiogenesis associated with the development of tumours and inflammatory lesions. Intracellular signaling, mediated via the cytoplasmic domain of CD248, promotes tumour growth and inflammation. CD248 knock-out mice and mice expressing CD248 lacking the cytoplasmic domain were resistant to tumour growth and inflammatory arthritis. Although signaling pathways have not been delineated, examination of the cytoplasmic domain of CD248 reveals three highly conserved putative phosphorylation sites and a PDZ-binding motif. We hypothesised that these structural features are important for CD248 function. We generated a variety of murine CD248 pcDNA constructs that encode CD248 with mutations in the cytoplasmic domain. We confirmed that all the mutants were transcribed and translated. Mutant proteins were expressed on the cell surface, in a similar manner to wildtype CD248. Introduction of some mutant forms CD248 into cells caused CD248 to exhibit different intracellular localisation and induced changes in cellular morphology compared to wildtype. Limited functional studies demonstrated CD248-dependent alterations in cellular MMP-9 production. The findings underline an important role of CD248’s cytoplasmic domain in regulating cellular morphology and function that may impact its role in health and disease. Extracellular interacting partners for CD248 have been previously described. Searches for intracellular partners interacting with the cytoplasmic domain have been less successful. Our results strongly suggest that these exist. Co-immunoprecipitation studies have revealed several putative interacting proteins that set the stage for future confirmatory and functional analyses. The cytoplasmic domain of CD248 is important to study as it holds much promise as a therapeutic target for proliferative disorders. The information gathered in this project may be used to delineate clinically relevant CD248 signaling pathways.
The Dialects of Magi
Creators: name: Thomson, N.P. (Ed.)
Publisher: name: Pacific Linguistics
Year: 1975

description: THE DIALECTS OF MAGI. 37 1. INTRODUCTION 37 1.1 Aim 37 1.2 Background 37 1.3 Materials and Method 41 2. RESULTS 43 2.1 The General Linguistic Picture 44 2.2 The Dialects of Magi 48 3. HISTORICAL INTERPRETATION 56Notes 58 4. APPENDICES 60 4.1 Comparative Basic Vocabulary Lists Across Magi Dialects 60 4.2 An Analysis of Route of Entry of Basic Vocabulary into Magi Dialects 76Bibliography 89Tables: I - Villages and Languages from which Wordlists Obtained 42II - Approximate Basic Vocabulary Cognate Percentages for Magi Dialects, and Associated Austronesian and Mailuan Languages 45III - An Analysis of Magi Vocabulary 52IV - Magi Villages and Dialects 55Diagrams: I - Schematic Representation of the Relationship Between Languages of the South Coast of South-East Papua 46II - Schematic Representation of the Relationships Between Magi Dialects 49Maps: Map 1 (Part 1) - The Magi Language Area (Eastern End) 38 Map 1 (Part 2) - The Magi Language Area (Western End) 39 Map 2 - Probable and Documented Language Movements in the Magi Area 40
Colonial Zoning, Community Equity, and the Planner: A Guide for Communities to Address Resident Exclusion Resulting from an Institutionalized Relationship with Land
Creators: name: East, Jacqueline
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Zoning
subject: Equity
subject: Planning
subject: Decolonization
subject: Diversity
subject: Inclusion
subject: Urban and Regional Planning
subject: FOS: Social and economic geography

description: Our relationship with land is shaped by the historical and ongoing processes of colonization and dispossession, which have established patterns of exclusion and inequality. Zoning regulations reflect and reinforce these patterns by privileging certain land uses and development patterns over others, often to benefit the dominant culture and to the detriment of those experiencing marginalization. The research examines the colonial foundations of zoning in Canada and takes inspiration from precedent equity in zoning work completed by the City of Edmonton, the American Planning Association, and the City of Ottawa. The study approaches the problem through design science research to explore the question of how planners, the writers and administrators of zoning, can recognize and act upon a colonial relationship with land that marginalizes some residents. The practice-based research generates and tests a prototype intervention for planners to access information about unjust land use rules as a precursor to public participation that centres the perspectives of those experiencing marginalization. The prototype evolves through application to three zoning bylaws – the District of Oak Bay, the Town of Sidney, and Salt Spring Island. The final prototype Zoning Equity Study Guide offers a mechanism to open the door guarding the institution of zoning and invites a relational path forward to deconstruct inequitable local laws that exclude.
The Development of Pigments Reflects Infrared Radiation from Gravel (Lateritic) Soils
Creators: name: Yotin Kallayalert
Publisher: name: Faculty of Science and Technology, Rajamangala University of Technology Thanyaburi
Year: 2023
Subjects: NIR reflective pigments
Calcined
Lateritic soil

description: Progress in Applied Science and Technology, 13, 1, 19-25
Examining Chronic Post-Stroke Aphasia Recovery Using Non-Invasive Brain Stimulation and Neuroimaging
Creators: name: Low, Trevor A
Publisher: name: Cumming School of Medicine
Year: 2024
Subjects: subject: Aphasia
subject: Stroke rehabilitation
subject: Transcranial magnetic stimulation
subject: Speech language therapy
subject: Magnetic resonance imaging
subject: Neuroscience
subject: Rehabilitation and Therapy
subject: Speech Pathology

description: Aphasia, an impairment in language processing, affects approximately one-third of stroke survivors immediately after stroke and up to 50% will have long-term impairments. Rehabilitation of aphasia at the chronic phase is possible, though outcomes are variable and often minimal. Novel therapeutic approaches and an increased understanding of the neurobiology supporting recovery are needed. Chapter Two assessed the safety and feasibility of combining repetitive transcranial magnetic stimulation (rTMS) with high-intensity Multi-Modality Aphasia Therapy (M-MAT) in chronic post-stroke aphasia (n=20). This novel combination therapy was determined to be feasible and safe in chronic post-stroke aphasia. On the basis of all participants benefiting from M-MAT regardless of rTMS allocation, we used resting-state fMRI (Chapter Three) and diffusion-weighted MRI (Chapter Four) to examine functional and structural connectivity associated with changes in speech production. In individuals that made positive, significant changes in naming, pre-treatment functional and structural connectivity of left hemisphere temporal and parietal language regions were associated with greater treatment-related improvement in naming. Additionally, naming improvements were associated with decreases in functional connectivity of bilateral posterior temporoparietal regions with frontoparietal, sensorimotor and visual networks at post-treatment. In Chapter Five, we conducted a randomized controlled trial investigating the efficacy of rTMS plus M-MAT on aphasia severity in a larger cohort of chronic stroke participants (n=43). Delivery of rTMS combined with M-MAT resulted in significant supplemental improvements in aphasia severity compared to sham plus M-MAT at follow-up. This demonstrates that rTMS is a promising adjuvant therapy for M-MAT in chronic stroke. Chapter Six investigated the neural basis of adjuvant rTMS effects using overt naming fMRI. Participants who received rTMS with M-MAT demonstrated dynamic functional reorganization over time, resulting in increased recruitment of left hemisphere perisylvian and temporoparietal regions at 15 weeks compared to sham. These data demonstrate potential mechanisms for the behavioural improvements observed following rTMS plus M-MAT. This thesis provides evidence to support the efficacy of rTMS plus M-MAT for improving chronic post-stroke aphasia. In addition, this thesis advances our understanding of the structural and functional brain architecture that supports aphasia recovery. These behavioural and neuroimaging results are important for the advancement of post-stroke aphasia rehabilitation.
The Safety and Feasibility of Transcranial Direct Current Stimulation for the Treatment of Chronic Cervicogenic Headaches
Creators: name: Jobin, Kaiden D.
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Neuromodulation
subject: Chronic Pain
subject: Cervicogenic Headache
subject: Exercise Therapy
subject: Transcranial Direct Current Stimulation
subject: Neck Strengthening Program
subject: Neuroscience
subject: Rehabilitation and Therapy

description: Cervicogenic headaches (CGH) are a highly debilitating condition whereby individuals primarily experience neck pain, headaches, and impaired neck function. Onset occurs frequently after whiplash injury, concussion, and degeneration of the cervical joints. Although therapies such as pharmacotherapy and exercise provide relief to some patients suffering from CGH, many patients do not find benefit from these interventions alone. Neuromodulation therapies such as transcranial direct current stimulation (tDCS) have recently shown promise in other headache and pain conditions. As such, we designed a double-blinded, sham-controlled, randomized trial to consider the safety and feasibility of tDCS combined with exercise therapy (ET) for patients with chronic CGH. Secondarily, we sought to explore the efficacy of active tDCS/+ET compared to sham tDCS/+ET on outcomes evaluating headache, pain, quality of life, and neck function. We found this intervention to be both safe and feasible for individuals with CGH, demonstrating high recruitment, retention, and adherence as well as no serious adverse events. Furthermore, we found significant group-time interactions favouring the active tDCS/+ET group with respect to headache intensity and frequency as well as pain and fine motor control of the deep cervical flexors. From these findings, a larger, adequately powered, clinical trial is warranted.
Impact of population growth and population ethics on climate change mitigation policy
Creators: name: Scovronick, Noah
name: Budolfson, Mark B.
name: Dennig, Francis
name: Fleurbaey, Marc
name: Siebert, Asher B.
name: Socolow, Robert H.
name: Spears, Dean
name: Wagner, Fabian
Publisher: name: Columbia University
Year: 2017
Subjects: Climate change mitigation
Population--Mathematical models
Social problems
Utilitarianism
Carbon dioxide
Population--Moral and ethical aspects
Climatic changes--Social aspects

description: Future population growth is uncertain and matters for climate policy: higher growth entails more emissions and means more people will be vulnerable to climate-related impacts. We show that how future population is valued importantly determines mitigation decisions. Using the Dynamic Integrated Climate-Economy model, we explore two approaches to valuing population: a discounted version of total utilitarianism (TU), which considers total wellbeing and is standard in social cost of carbon dioxide (SCC) models, and of average utilitarianism (AU), which ignores population size and sums only each time period’s discounted average wellbeing. Under both approaches, as population increases the SCC increases, but optimal peak temperature decreases. The effect is larger under TU, because it responds to the fact that a larger population means climate change hurts more people: for example, in 2025, assuming the United Nations (UN)-high rather than UN-low population scenario entails an increase in the SCC of 85% under TU vs. 5% under AU. The difference in the SCC between the two population scenarios under TU is comparable to commonly debated decisions regarding time discounting. Additionally, we estimate the avoided mitigation costs implied by plausible reductions in population growth, finding that large near-term savings ($billions annually) occur under TU; savings under AU emerge in the more distant future. These savings are larger than spending shortfalls for human development policies that may lower fertility. Finally, we show that whether lowering population growth entails overall improvements in wellbeing—rather than merely cost savings—again depends on the ethical approach to valuing population.
The Scholarly Communication Platform Framework
Creators: name: Van den Boomen, Bram
name: Van Eck, Nees Jan
name: Waltman, Ludo
name: Ross-Hellauer, Tony
name: Horbach, Serge P.J.M.
Publisher: name: Zenodo
Year: 2023
Subjects: Scholarly Communication Platform Framework
Platform Assertion Document data model
Scholarly Communication Platform Ontology
SCPO
scholarly communication
scholarly communication platforms
journals
preprint servers
peer review platforms
Linked data
Semantic Web
machine-readable

description: The Scholarly Communication Platform Framework is a high-level structured language that enables the exchange of information about platforms for scholarly communication. The framework consists of two core elements: The Platform Assertion Document (PAD) data model, which facilitates the exchange of information about scholarly communication platforms in a machine-readable and traceable way. The Scholarly Communication Platform (SCPO) Ontology for describing specific properties of scholarly communication platforms.
Across the tree of life, radiation resistance is governed by antioxidant Mn2+, gauged by paramagnetic resonance
Creators: name: Sharma, Ajay
name: Gaidamakova, Elena K.
name: Grichenko, Olga
name: Matrosova, Vera Y.
name: Hoeke, Veronika
name: Klimenkova, Polina
name: Conze, Isabel H.
name: Volpe, Robert P.
name: Tkavc, Rok
name: Gostinčar, Cene
name: Gunde-Cimerman, Nina
name: DiRuggiero, Jocelyne
name: Shuryak, Igor
name: Ozarowski, Andrew
name: Hoffman, Brian M.
name: Daly, Michael J.
Publisher: name: Columbia University
Year: 2017
Subjects: Ionizing radiation
Electron paramagnetic resonance spectroscopy
Manganese
DNA repair
Deinococcus
Molecular biology

description: Despite concerted functional genomic efforts to understand the complex phenotype of ionizing radiation (IR) resistance, a genome sequence cannot predict whether a cell is IR-resistant or not. Instead, we report that absorption-display electron paramagnetic resonance (EPR) spectroscopy of nonirradiated cells is highly diagnostic of IR survival and repair efficiency of DNA double-strand breaks (DSBs) caused by exposure to gamma radiation across archaea, bacteria, and eukaryotes, including fungi and human cells. IR-resistant cells, which are efficient at DSB repair, contain a high cellular content of manganous ions (Mn2+) in high-symmetry (H) antioxidant complexes with small metabolites (e.g., orthophosphate, peptides), which exhibit narrow EPR signals (small zero-field splitting). In contrast, Mn2+ ions in IR-sensitive cells, which are inefficient at DSB repair, exist largely as low-symmetry (L) complexes with substantially broadened spectra seen with enzymes and strongly chelating ligands. The fraction of cellular Mn2+ present as H-complexes (H-Mn2+), as measured by EPR of live, nonirradiated Mn-replete cells, is now the strongest known gauge of biological IR resistance between and within organisms representing all three domains of life: Antioxidant H-Mn2+ complexes, not antioxidant enzymes (e.g., Mn superoxide dismutase), govern IR survival. As the pool of intracellular metabolites needed to form H-Mn2+ complexes depends on the nutritional status of the cell, we conclude that IR resistance is predominantly a metabolic phenomenon. In a cross-kingdom analysis, the vast differences in taxonomic classification, genome size, and radioresistance between cell types studied here support that IR resistance is not controlled by the repertoire of DNA repair and antioxidant enzymes.
Elucidating the role of tcf15 in somite development
Creators: name: Lim, Nicholas Farn Wei
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Tcf15
subject: Zebrafish
subject: Developmental
subject: Biology
subject: Somite
subject: Genetics
subject: FOS: Biological sciences
subject: Biology--Molecular

description: Somites are transient embryonic structures that give rise to the axial musculoskeletal system. Eventually, the somite gives rise to three distinct compartments: the dermatome, myotome, and sclerotome. These compartments give rise to the skin, skeletal muscles, and the axial skeleton, respectively. Thus, proper formation of somitic compartment is necessary for a functional body. Despite many early studies elucidating the development of the somite, little is known about the regulator of somite compartment proportion. Here I characterized the basic helix-loop-helix transcription factor, tcf15, as a key regulator of somitic compartments in zebrafish. I showed that tcf15 expression is highly dynamic during somite development, with initial robust expression throughout the presomitic mesoderm, followed by restricted expression in the dermomyotome and ultimately in dermomyotome-derived muscle progenitors and in sclerotome-derived tenocytes along the somite boundary. Through mutant analysis, I found that loss of tcf15 results in a reduction in the pax7a+ dermomyotome and the myoD+ myotome compartment accompanied by an expansion of the nkx3.1+ sclerotome. Interestingly, migration of sclerotome cells and the development of sclerotome-derived cells such as tenocytes and fin mesenchymal cells were unaffected in tcf15 mutants. To manipulate Tcf15 activity, I developed various gain-of-function and loss-of function tools. However, the broad application of these tools was limited by technical challenges. Nonetheless, by combining the expression and mutant analysis, my results suggest that Tcf15 functions as an important regulator of somite compartmentalization in zebrafish, promoting the dermomyotome/myotome fate while repressing the sclerotome fate.
การพัฒนาผลิตภัณฑ์ขนมขบเคี้ยวชนิดพองกรอบที่ผลิตจากแป้งข้าวกล้องสังข์หยดพัทลุง ด้วยกระบวนการเอกซ์ทรูชันเสริมอินูลิน
Creators: name: สุธาสินี ทองนอก
Publisher: name: คณะเทคโนโลยีการเกษตร มหาวิทยาลัยราชภัฏมหาสารคาม
Year: 2023
Subjects: ขนมพองกรอบ
อินูลิน
แป้งข้าวสังข์หยด
เอกซ์ทรูชัน

description: วารสารเกษตรพระวรุณ, 20, 1, 19-26
Search predicts and changes patience in intertemporal choice
Creators: name: Reeck, Crystal
name: Wall, Daniel
name: Johnson, Eric J.
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Delay discounting (Psychology)
subject: Decision making
subject: Psychology
subject: FOS: Psychology
subject: Choice (Psychology)
subject: Patience

description: Intertemporal choice impacts many important outcomes, such as decisions about health, education, wealth, and the environment. However, the psychological processes underlying decisions involving outcomes at different points in time remain unclear, limiting opportunities to intervene and improve people’s patience. This research examines information-search strategies used during intertemporal choice and their impact on decisions. In experiment 1, we demonstrate that search strategies vary substantially across individuals. We subsequently identify two distinct search strategies across individuals. Comparative searchers, who compare features across options, discount future options less and are more susceptible to acceleration versus delay framing than integrative searchers, who integrate the features of an option. Experiment 2 manipulates search using an unobtrusive method to establish a causal relationship between strategy and choice, randomly assigning participants to conditions promoting either comparative or integrative search. Again, comparative search promotes greater patience than integrative search. Additionally, when participants adopt a comparative search strategy, they also exhibit greater effects of acceleration versus delay framing. Although most participants reported that the manipulation did not change their behavior, promoting comparative search decreased discounting of future rewards substantially and speeded patient choices. These findings highlight the central role that heterogeneity in psychological processes plays in shaping intertemporal choice. Importantly, these results indicate that theories that ignore variability in search strategies may be inadvertently aggregating over different subpopulations that use very different processes. The findings also inform interventions in choice architecture to increase patience and improve consumer welfare.