cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Selective Targeting of the Repressive Transcription Factors YY1 and cMyc to Disrupt Quiescent Human Immunodeficiency Viruses
Creators: name: Margolis, David
name: Barton, Kirston
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Quiescent HIV-1 infection of resting CD4+ T cells is an obstacle to eradication of HIV-1 infection. These reservoirs are maintained, in part, by repressive complexes that bind to the HIV-1 long terminal repeat (LTR) and recruit histone deacetylases (HDACs). cMyc and YY1 are two transcription factors that are recruited as part of well-described, distinct complexes to the HIV-1 LTR and in turn recruit HDACs. In prior studies, depletion of single factors that recruit HDAC1 in various cell lines was sufficient to upregulate LTR activity. We used short hairpin RNAs (shRNAs) to test the effect of targeted disruption of a single transcription factor on quiescent proviruses in T cell lines. In this study, we found that depletion of YY1 significantly increases mRNA and protein expression from the HIV-1 promoter in some contexts, but does not affect HDAC1, HDAC2, HDAC3, or acetylated histone 3 occupancy of the HIV-1 LTR. Conversely, depletion of cMyc or cMyc and YY1 does not significantly alter the level of transcription from the LTR or affect recruitment of HDACs to the HIV-1 LTR. Furthermore, global inhibition of HDACs with the HDAC inhibitor suberoylanilide hydroxamic acid (SAHA) enhanced the increase in LTR transcription in cells that were depleted of YY1.These findings show that despite prior isolated findings, redundancy in repressors of HIV-1 LTR expression will require selective targeting of multiple restrictive mechanisms to comprehensively induce the escape of quiescent proviruses from latency.
Galaxy cluster lensing masses in modified lensing potentials
Creators: name: Barreira, Alexandre
name: Li, Baojiu
name: Jennings, Elise
name: Merten, Julian
name: King, Lindsay
name: Baugh, Carlton
name: Pascoli, Silvia
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We determine the concentration-mass relation of 19 X-ray selected galaxy clusters from the CLASH survey in theories of gravity that directly modify the lensing potential. We model the clusters as NFW haloes and fit their lensing signal, in the Cubic Galileon and Nonlocal gravity models, to the lensing convergence profiles of the clusters. We discuss a number of important issues that need to be taken into account, associated with the use of nonparametric and parametric lensing methods, as well as assumptions about the background cosmology. Our results show that the concentration and mass estimates in the modified gravity models are, within the errorbars, the same as in $Λ$CDM. This result demonstrates that, for the Nonlocal model, the modifications to gravity are too weak at the cluster redshifts, and for the Galileon model, the screening mechanism is very efficient inside the cluster radius. However, at distances $\sim \left[2-20\right] {\rm Mpc}/h$ from the cluster center, we find that the surrounding force profiles are enhanced by $\sim20-40\%$ in the Cubic Galileon model. This has an impact on dynamical mass estimates, which means that tests of gravity based on comparisons between lensing and dynamical masses can also be applied to the Cubic Galileon model.
description: 21 pages, 9 figures, 2 tables. Comments welcome
title: Measurement and prognostic value of the left ventricular mass in newborns with congenital heart defects using CT-angiographies of the chest
Creators: name: May, Matthias
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Cardiac
subject: Paediatric
subject: Interventional non-vascular
subject: CT
subject: MR
subject: Percutaneous
subject: Dosimetry
subject: Ablation procedures
subject: Computer Applications-General
subject: Congenital
subject: Cancer
subject: Dosimetric comparison

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The left ventricular mass is an important factor for the therapeutic strategy in patients with complex congenital heart defects 1 . Besides echocardiography and MRI,CT angiographies (CTA)of the chestplayan increasing role in the preoperative...
Short Communication: Initiation of an Abacavir-Containing Regimen in HIV-Infected Adults Is Associated with a Smaller Decrease in Inflammation and Endothelial Activation Markers Compared to Non-Abacavir-Containing Regimens
Creators: name: Debanne, Sara M.
name: Tisch, Daniel J.
name: McComsey, Grace A.
name: Wohl, David A.
name: Hileman, Corrilynn O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Abacavir has been associated with myocardial infarction in several studies. This may be related to inflammation and endothelial cell activation. We compared changes in inflammation and endothelial activation markers between antiretroviral-naive adults initiating zidovudine, lamivudine, abacavir, and nonnucleoside reverse transcriptase inhibitor (NNRTI) or this regimen without abacavir. Changes in soluble tumor necrosis factor receptors-I, -II (sTNFR-I, -II), high sensitivity C-reactive protein, and soluble vascular cell adhesion molecule-1 (sVCAM-1) from baseline (pre-ART) to a second time point about 24 weeks after initiating antiretroviral therapy (ART) were compared between groups using multivariable linear regression. A total of 37 met eligibility criteria; 12 received abacavir. The median (interquartile range) age was 37 years (27–45). Most were men (32/37), African-American (15/37), or white (15/37). The median nadir CD4+ and baseline HIV-1 RNA were 230 cells/mm3 (180–301) and 82,642 copies/ml (34,400–204,703). In all, 15/30 smoked, 7/37 had hypertension, 1/37 had diabetes, and 1/37 had hyperlipidemia. None had coronary or renal disease. Changes in CD4+ and HIV-1 RNA level and timing of stored samples with regard to ART initiation were not different between groups. In univariable analysis, log transformed percent change in sTNFR-I (p=0.05) and -II (p=0.04) showed significant between-group differences and trended toward significance for sVCAM-1 (p=0.08). These markers decreased less in the abacavir group. After adjustment for confounders, significantly less decrease for sTNFR-II and sVCAM-1 was seen for those receiving the abacavir-containing regimen. When taken with an NNRTI, abacavir induced a smaller decrease in inflammation biomarkers in this cohort, suggesting a possible proinflammatory effect of this nucleoside analogue.
(100980) James Harding
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 1 of A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials
Creators: name: McBride, Angela
name: Vuong, Nguyen Lam
name: Van Hao, Nguyen
name: Huy, Nguyen Quang
name: Chanh, Ho Quang
name: Chau, Nguyen Thi Xuan
name: Nguyet, Nguyen Minh
name: Ming, Damien K.
name: Ngoc, Nguyen Thanh
name: Nhat, Phung Tran Huy
name: Phong, Nguyen Thanh
name: Tai, Luong Thi Hue
name: Tho, Phan Vinh
name: Trung, Dinh The
name: Tam, Dong Thi Hoai
name: Trieu, Huynh Trung
name: Geskus, Ronald Bertus
name: Llewelyn, Martin J.
name: Thwaites, C. Louise
name: Yacoub, Sophie
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1: Table S1. Clinical data by patients with and without comorbidities. Table S2. Clinical data by patients who were transferred from other hospitals and those admitted to HTD. Table S3. Results from models with baseline SOFA and delta SOFA score. All parameters are estimated from models with only one predictor ‘baseline SOFA score’ or ‘delta SOFA score’ with a linear effect. Logistic regression model is used for binary endpoint (ICU admission, mechanical ventilation, vasopressor support, haemofiltration, and mortality), Cox proportional hazard model is used for time-to-event endpoints (ICU discharge, hospital discharge, and stop IV fluid use), and linear regression model is used for total volume of IV fluid use with log-transformation. The estimates (OR, HR, or MR) and 95% CIs are reported for each point increase of baseline SOFA or delta SOFA score. AUC, area under the curve; CI; confidence interval; Est, estimate; HR, hazard ratio; ICU, intensive care unit; IV, intravenous fluid; MR, mean ratio; OR, odds ratio. Table S4. Association between baseline mSOFA & delta mSOFA scores and endpoints by patients with and without comorbidities. Table S5. Association between baseline mSOFA & delta mSOFA scores and endpoints by patients who were transferred from other hospitals and those admitted to HTD. Table S6. Association between Pulse Pressure and narrow Pulse Pressure (Pulse Pressure < 20 mmHg) and endpoints.
title: Quality control of mammographic images in Slovenian breast cancer screening programme DORA
Creators: name: Nemanič, Polona
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Breast
subject: Radiographers
subject: Mammography
subject: Education

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: DORA programme is Slovenian population-based breast cancer screening programme which invites women aged 50 to 69 years to screening mammography every two years. Programme strictly follows European guidelines for quality assurance in breast cancer...
Acute HIV-1 Infection in the Southeastern United States: A Cohort Study
Creators: name: McGee, Kara S.
name: Kuruc, Joann D.
name: Ferrari, Guido
name: Mckellar, Mehri S.
name: Eron, Joseph J.
name: Hicks, Charles B.
name: Gay, Cynthia L.
name: Cope, Anna B.
name: Kerkau, Melissa G.
name: Margolis, David M.
name: Fiscus, Susan A.
name: Hurt, Christopher B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: In 1998 a collaboration between Duke University and the University of North Carolina, Chapel Hill (UNC) was founded to enhance identification of persons with acute HIV-1 infection (AHI). The Duke-UNC AHI Research Consortium Cohort consists of patients ≥18 years old with a positive nucleic acid amplification test (NAAT) and either a negative enzyme immunoassay (EIA) test or a positive EIA with a negative/indeterminate Western blot. Patients were referred to the cohort from acute care settings and state-funded HIV testing sites that use NAAT testing on pooled HIV-1 antibody-negative samples. Between 1998 and 2010, 155 patients with AHI were enrolled: 81 (52%) African-Americans, 63 (41%) white, non-Hispanics, 137 (88%) males, 108 (70%) men who have sex with men (MSM), and 18 (12%) females. The median age was 27 years (IQR 22–38). Most (n=138/155) reported symptoms with a median duration of 17.5 days. The median nadir CD4 count was 408 cells/mm3 (IQR 289–563); the median observed peak HIV-1 level was 726,859 copies/ml (IQR 167,585–3,565,728). The emergency department was the most frequent site of initial presentation (n=55/152; 3 missing data). AHI diagnosis was made at time of first contact in 62/137 (45%; 18 missing data) patients. This prospectively enrolled cohort is the largest group of patients with AHI reported from the Southeastern United States. The demographics reflect the epidemic of this geographic area with a high proportion of African-Americans, including young black MSM. Highlighting the challenges of diagnosing AHI, less than half of the patients were diagnosed at the first healthcare visit. Women made up a small proportion despite increasing numbers in our clinics.
title: Mammography and ultrasound usefulness for breast cancer diagnosis in elderly women with and without symptoms: our experience
Creators: name: Lorenzon, Michele
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Breast
subject: Mammography
subject: Ultrasound
subject: Screening
subject: Diagnostic procedure
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The risk of breast cancer increases with age Fig. 1 , thus more than 30% of breast cancers are diagnosed in women 70 years old or older [1]. Even though the American Cancer Society recommends that screening mammography should continue as long as a...
A measurement study of the Internet ping traces.
Creators: name: Attack, CrossPoint
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 460407
subject: System and network security

description: We provide a dataset that corresponds to the CrossPoint Attacks thesis currently under review by USENIX Security 2024. This dataset presents empirical findings on CrossPoint Attacks in the context of the Internet (with careful ethical considerations; for details, please refer to our paper). The corresponding thesis will be added upon completion of the double-blind review process. Enclosed within this file are the ping results gathered for multiple Internet paths over several months, which can also be used in understanding the congestion of the Internet.
Linked Component Analysis from Matrices to High Order Tensors: Applications to Biomedical Data
Creators: name: Zhou, Guoxu
name: Zhao, Qibin
name: Zhang, Yu
name: Adalı, Tülay
name: Xie, Shengli
name: Cichocki, Andrzej
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Machine Learning (cs.LG)
subject: Numerical Analysis (math.NA)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: With the increasing availability of various sensor technologies, we now have access to large amounts of multi-block (also called multi-set, multi-relational, or multi-view) data that need to be jointly analyzed to explore their latent connections. Various component analysis methods have played an increasingly important role for the analysis of such coupled data. In this paper, we first provide a brief review of existing matrix-based (two-way) component analysis methods for the joint analysis of such data with a focus on biomedical applications. Then, we discuss their important extensions and generalization to multi-block multiway (tensor) data. We show how constrained multi-block tensor decomposition methods are able to extract similar or statistically dependent common features that are shared by all blocks, by incorporating the multiway nature of data. Special emphasis is given to the flexible common and individual feature analysis of multi-block data with the aim to simultaneously extract common and individual latent components with desired properties and types of diversity. Illustrative examples are given to demonstrate their effectiveness for biomedical data analysis.
description: 20 pages, 11 figures, Proceedings of the IEEE, 2015
title: Quantitative T2 relaxation analysis of articular cartilage of knee joint in patients with knee pain and healthy individuals at 1.5T MRI
Creators: name: Tulasi, Reddy
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Osteoporosis
subject: Imaging sequences
subject: MR
subject: Musculoskeletal joint

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Articular cartilage damage is common in the knee joint and if untreated can become symptomatic and progress to osteoarthritis. Conventional radiography and standard magnetic resonance imaging (MRI) can give limited information to detect early stages...
title: Decision-making in surgery of small bowel Crohn disease: the diagnostic role of magnetic resonance enterography
Creators: name: Zanardi, Sara
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Abdomen
subject: Gastrointestinal tract
subject: MR
subject: Colonography MR
subject: Surgery
subject: Inflammation
subject: Pathology

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate the diagnostic accuracy (DA) of the magnetic resonance enterography (MRE) in preoperative study of small bowel Crohn disease (CD) to detect the signs of complicated disease (significant stenosis and fistula) on the basis of the...
Immunologic Risk Factors for Early Mortality After Starting Antiretroviral Therapy in HIV-Infected Zambian Children
Creators: name: Rainwater-Lovett, Kaitlin
name: Nkamba, Hope C.
name: Mubiana-Mbewe, Mwangelwa
name: Moss, William J.
name: Moore, Carolyn Bolton
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: To explore immunologic risk factors for death within 90 days of highly active antiretroviral therapy (HAART) initiation, CD4+ and CD8+ T cell subsets were measured by flow cytometry and characterized by logistic regression in 149 Zambian children between 9 months and 10 years of age enrolled in a prospective, observational study of the impact of HAART on measles immunity. Of 21 children who died during follow-up, 17 (81%) had known dates of death and 16 (76%) died within 90 days of initiating HAART. Young age and low weight-for-age z-scores were associated with increased risks of mortality within 90 days of starting HAART, whereas CD4+ T cell percentage was not associated with mortality. After adjusting for these factors, each 10% increase in CD8+ effector T cells increased the odds of overall mortality [OR=1.43 (95% CI: 1.08, 1.90)] and was marginally associated with early mortality [OR=1.29 (95% CI: 0.97, 1.72)]. Conversely, each 10% increase in CD4+ central memory T cells decreased the odds of overall [OR=0.06 (95% CI: 0.01, 0.59)] and early mortality [OR=0.09 (95% CI: 0.01, 0.97)]. Logistic regression prediction models demonstrated areas under the receiver-operator characteristic curves of ≥85% for early and overall mortality, with bootstrapped sensitivities of 82–85% upon validation, supporting the predictive accuracy of the models. CD4+ and CD8+ T cell subsets may be more accurate predictors of early mortality than CD4+ T cell percentages and could be used to identify children who would benefit from more frequent clinical monitoring after initiating HAART.
(100981) Jane Harding
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Application of neurite orientation dispersion and density imaging (NODDI) in the basal ganglia nucleus in Wilson’s disease
Creators: name: Song, Yukun
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR-Diffusion/Perfusion
subject: MR-Functional imaging
subject: MR
subject: Imaging sequences

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To quantitatively evaluate changes of neurite orientation dispersion and density imaging (NODDI) in the basal ganglia nucleus in Wilson’s disease (WD), and assess the diagnostic value of NODDI...
Randomness in post-selected events
Creators: name: Thinh, Le Phuc
name: de la Torre, Gonzalo
name: Bancal, Jean-Daniel
name: Pironio, Stefano
name: Scarani, Valerio
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Bell inequality violations can be used to certify private randomness for use in cryptographic applications. In photonic Bell experiments, a large amount of the data that is generated comes from no-detection events and presumably contains little randomness. This raises the question as to whether randomness can be extracted only from the smaller post-selected subset corresponding to proper detection events, instead of from the entire set of data. This could in principle be feasible without opening an analogue of the detection loophole as long as the min-entropy of the post-selected data is evaluated by taking all the information into account, including no-detection events. The possibility of extracting randomness from a short string has a practical advantage, because it reduces the computational time of the extraction. Here, we investigate the above idea in a simple scenario, where the devices and the adversary behave according to i.i.d. strategies. We show that indeed almost all the randomness is present in the pair of outcomes for which at least one detection happened. We further show that in some cases applying a pre-processing on the data can capture features that an analysis based on global frequencies only misses, thus resulting in the certification of more randomness. We then briefly consider non-i.i.d strategies and provide an explicit example of such a strategy that is more powerful than any i.i.d. one even in the asymptotic limit of infinitely many measurement rounds, something that was not reported before in the context of Bell inequalities.
description: similar to published version, new section (III) on photonic experiments
Additional file 1 of Nutritional adequacy of meals and commissary items provided to individuals incarcerated in a southwest, rural county jail in the United States
Creators: name: Lopez, Nanette V.
name: Spilkin, Ary
name: Brauer, Julianne
name: Phillips, Rachelle
name: Kuss, Bonnie
name: Delio, Gabrielle
name: Camplain, Ricky
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Computational Biology

description: Additional file 1: Supplementary Table 1. Seven-day Cycle Menu Items that are Missing from NutritionCalc® Plus and the Comparable Item Chosen.
title: Utopien, Visionen und Ideen
title: was Menschen im Furttal während 130 Jahren bewegte
titleType: Subtitle
Creators: name: Maurer, Ursula
name: Wüthrich, Lucas Heinrich
name: Brütsch, Max
name: Wegmann, Werner
name: Zollinger, Emil
name: Staub, Peter
name: Günter, Hans
name: Ehrsam, Hans
name: Siegenthaler, Rainer
name: Hegglin, Thomas
name: Wyss, Pit
name: Eppler, Georg
Publisher: name: Zentralbibliothek Zürich
Year: 2004
Subjects: subject: 710 Städtebau, Raumplanung, Landschaftsgestaltung
subject: 949 Geschichte anderer Teile Europas
subject: Furttal
subject: Furtbach
subject: Heimatkunde
subject: Raumentwicklung

description: Jubiläumsschrift zum 50 Jahre-Jubiläum der HVF, Heimatkundliche Vereinigung Furttal
description: Enthält: Vorwort zum 50 Jahre-Jubiläum der HVF Heimatkundliche Vereinigung Furttal von Ursula Maurer ; Schiffbarmachung des Furtbaches von Lucas Wüthrich ; Warum die Strafanstalt Regensdorf heute nicht im Riet steht von Max Brütsch ; Dorfumfahrung Boppelsen von Werner Wegmann ; Eine öffentliche Badeanstalt im Watter Furtbach von Emil Zollinger ; Pferderennplatz in Dällikon von Peter Staub ; Gemeindezentrum und Mehrzweckgebäude in Buchs von Ursula Maurer ; Wasserverbindungen von und zur Limmat von Hans Günter ; Ausbau des Emma Kunz Zentrum von Hans Ehrsam ; Das Furttal mit direktem Eisenbahnanschluss an die weite Welt von Rainer Siegenthaler ; Sport- und Touristikflugplatz Dällikon von Peter Staub ; Studienstadt Otelfingen von Thomas Hegglin ; Ein Hotelprojekt auf der Lägern Hochwacht von Pit Wyss ; Der unendliche Traum eines Freiluftschwimmbades in Regensdorf von Lucas Wüthrich ; Furttal-Hochleistungsstrasse von Georg Eppler ; «Boldern» liegt heute nicht am Katzensee von Max Brütsch ; Kurzhinweise auf weitere Ideen und Projekte von Hans Günter
Determination of pion distribution amplitudes from the electromagnetic form factor with the data-driven dispersion relation
Creators: name: Chai, Jian
name: Cheng, Shan
name: Hua, Jun
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the pion electromagnetic form factor in the modulus squared dispersion relation, and do the model independent extraction of the most important nonperturbative parameters in pion light-cone distribution amplitude. The motivation of this work is the recent measurement of timelike form factor in the resonant regions, which makes up the piece lacking solid QCD-based calculation. With the perturbative QCD calculation up to next-to-leading-order QCD corrections and twist four level of meson distribution amplitudes, we obtain the chiral mass of pion meson as $m_0^π(1 \, {\rm GeV}) = 1.31^{+0.27}_{-0.30} \, {\rm GeV}$. More accuracy measurement of the timelike form factor are desirable to help us to determine the lowest gegenbauer moments in pion distribution amplitudes with the data-driven dispersion relation method developed in this work.
description: 9pages, 6 figures, 1 table
Testing SALT Approximations with Numerical Radiation Transfer Code Part 1: Validity and Applicability
Creators: name: Carr, Cody
name: Michel-Dansac, Leo
name: Blaizot, Jeremy
name: Scarlata, Claudia
name: Henry, Alaina
name: Verhamme, Anne
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Absorption line spectroscopy offers one of the best opportunities to constrain the properties of galactic outflows and the environment of the circumgalactic medium. Extracting physical information from line profiles is difficult, however, for the physics governing the underlying radiation transfer is complicated and depends on many different parameters. Idealized analytical models are necessary to constrain the large parameter spaces efficiently, but are typically plagued by model degeneracy and systematic errors. Comparison tests with idealized numerical radiation transfer codes offer an excellent opportunity to confront both of these issues. In this paper, we present a detailed comparison between SALT, an analytical radiation transfer model for predicting UV spectra of galactic outflows, with the numerical radiation transfer software, RASCAS. Our analysis has lead to upgrades to both models including an improved derivation of SALT and a customizable adaptive mesh refinement routine for RASCAS. We explore how well SALT, when paired with a Monte Carlo fitting procedure, can recover flow parameters from non-turbulent and turbulent flows. When the velocity and density gradients are excluded, we find that flow parameters are well recovered from high resolution (20 $\rm{km}$ $\rm{s}^{-1}$) data and moderately well from medium resolution (100 $\rm{km}$ $\rm{s}^{-1}$) data without turbulence at a S/N = 10, while derived quantities (e.g., mass outflow rates, column density, etc.) are well recovered at all resolutions. In the turbulent case, biased errors emerge in the recovery of individual parameters, but derived quantities are still well recovered.
Incidence and Clinical Features of Cerebrovascular Disease Among HIV-Infected Adults in the Southeastern United States
Creators: name: Napravnik, Sonia
name: Floris-Moore, Michelle
name: Eron, Joseph J.
name: Vinikoor, Michael J.
name: Huang, David Y.
name: Wilson, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: With aging of the HIV-infected population, non-AIDS conditions such as cardiovascular disease (CVD) now account for substantial mortality and morbidity. While myocardial infarction is the major outcome of interest in the field of HIV and CVD, cerebrovascular disease remains understudied, especially in the Southeastern United States. We determined the incidence and clinical features of cerebrovascular events (CVE) in a large HIV clinical cohort in North Carolina (NC). A total of 2,515 HIV-infected adults contributed a median of 4.5 years (IQR: 2.0, 7.8) of follow-up. Fifty-three CVEs were adjudicated for an incidence rate of 3.87 per 1,000 person-years (95% CI: 2.90, 5.06). The ischemic stroke incidence was 2.26 per 1,000 person-years (95% CI: 1.53, 3.21), approximately 1.5 times the rate of a population-based cohort in NC. At the time of CVE, the median age was 48 years (IQR: 42, 55). Of ischemic strokes 76% resulted from large artery atherosclerosis or small vessel (lacunar) disease. In multivariable analyses, age, hypertension, dyslipidemia, recent CD4+ cell count ≤200 cells/mm3, and recent HIV RNA >400 copies/ml were associated with an increased risk of CVE. Antiretroviral therapy (ART) was not associated with the risk of CVE. We concluded that in the post-ART era, HIV-infected individuals appear to be at moderately increased risk of stroke. Prevention of CVEs in this population will require modification of traditional CVD risk factors and early, effective treatment of HIV infection.
title: Transarterial chemoembolisation (TACE) with degradable starch microspheres (DSM) and anthracycline in patients with locally advanced HCC: safety and efficacy
Creators: name: Gross, Alexander
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Liver
subject: Interventional non-vascular
subject: Oncology
subject: Catheter arteriography
subject: CT
subject: MR
subject: Chemoembolisation
subject: Embolisation
subject: Treatment effects
subject: Cancer
subject: Cirrhosis
subject: Toxicity

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Transarterial chemoembolisation (TACE) is an integral part of the treatment for unresectable hepatocellular carcinoma (HCC). In their joint guideline, the European Association for the Study of the Liver (EASL) and the European Organisation for...
Low Prevalence of Antiretroviral Resistance Among HIV Type 1-Positive Prisoners in the Southeast United States
Creators: name: Rosen, David
name: Menezes, Prema
name: Sebastian, Joseph
name: Wohl, David A.
name: Kiziah, Nichole
name: White, Becky
name: Eron, Joseph J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Drug-resistant HIV complicates management of HIV infection. Although an estimated 14% of all HIV-positive persons pass through a prison or jail in the United States each year, little is known about the overall prevalence of antiretroviral (ARV) resistance in incarcerated persons. All genotypic sequence data on HIV-positive prisoners in the North Carolina (NC) Department of Corrections (DOC) were obtained from LabCorp. Screening for major resistance mutations in protease (PI) and reverse transcriptase (NRTI and NNRTI) was done using Genosure and the Stanford HIV Database. For subjects with multiple genotype reports, each mutation was counted only once and considered present on all subsequent genotypes. Between October 2006 and February 2010, the NC DOC incarcerated 1,911 HIV+ individuals of whom 19.2% (n=367) had at least one genotype performed. The overall prevalence of a major resistance mutation was 28.3% (95% CI 23.7, 33.0). Among prisoners ever exposed to an ARV during incarceration (n=329) prevalence of a major resistance mutation was 29.8% (95% CI 24.9, 34.7); resistance by class was 20.4% (95% CI 16.0, 24.7) for NRTIs, 19.8% (95% CI 15.5, 24.1) for NNRTIs, and 8.8% (95% CI 5.8,11.9) for PIs. Single class drug resistance was most prevalent at 14.2% (10.2,17.7) followed by dual 12.5% (I8.9,16.0) and triple class 3.3% (1.4,5.3) resistance. The three most prevalent mutations were K103N 15.8% (12.0, 20.2), M184V 14.3% (10.7,18.5), and M41L 4.9% (2.8,7.8). In the NC DOC ARV resistance prevalence, dual and triple class drug resistance was moderate over the study period. Resistance to PIs was lower than NNRTIs and NRTIs, likely reflecting higher usage of these two classes or a lower barrier to resistance.
title: Dynamic, interleaved NMR measurements of perfusion, deoxymyoglobin and phosphorylated metabolites on a 3 T clinical scanner
Creators: name: Lopez Kolkovsky, Alfredo
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Extremities
subject: MR
subject: MR-Diffusion/Perfusion
subject: MR-Spectroscopy
subject: Experimental investigations
subject: Imaging sequences
subject: Ischaemia / Infarction
subject: Outcomes

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: NMR allows to investigate multiple aspects of physiological parameters in vivo such as regional perfusion, blood and tissue oxygenation, intracellular pH or high-energy phosphate metabolism. Classical NMR acquisition schemes rarely explore more than...
Spinorial Wheeler-DeWitt wave functions inside black hole horizons
Creators: name: Kan, Nahomi
name: Aoyama, Takuma
name: Shiraishi, Kiyoshi
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We revisit the solutions of the Wheeler-DeWitt (WDW) equation inside the horizons of spherical black holes and planar topological black holes in arbitrary dimensions. For these systems, the solutions of the equations are found to have the same form. Therefore, Yeom's Annihilation-to-nothing interpretation can be applied to each case. We have introduced the Dirac-type WDW equations into quantum cosmology in a recent paper, so we also apply our formulation to the quantum theory of the interior of the black hole in order to obtain the solution of the spinorial wave function. The shape of the wave packet of the spinorial WDW wave function indicates that the variation of Yeom's interpretation holds in this scheme.
description: 16 pages, 3 figures. Final version
The effect of bound state dressing in laser assisted radiative recombination
Creators: name: Müller, Robert Alexander
name: Seipt, Daniel
name: Fritzsche, Stephan
name: Surzhykov, Andrey
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We present a theoretical study on the recombination of a free electron into the ground state of a hydrogen-like ion in the presence of an external laser field. Emphasis is placed on the effects caused by the laser dressing of the residual ionic bound state. To investigate how this dressing affects the total and angle-differential cross section of laser assisted radiative recombination (LARR) we apply first-order perturbation theory and the separable Coulomb-Volkov-continuum ansatz. Using this approach detailed calculations were performed for low-$Z$ hydrogen like ions and laser intensities in the range from $I_L=10^{11}\text{W/cm}^2$ to $I_L=10^{13}\text{W/cm}^2$. It is seen that the total cross section as a function of the laser intensity is remarkably affected by the bound state dressing. Moreover the laser dressing becomes manifest as asymmetries in the angular distribution and the (energy) spectrum of the emitted recombination photons.
description: 9 pages, 5 figures
Outcomes of Second Combination Antiretroviral Therapy Regimens Among HIV-Infected Persons in Clinical Care: A Multicenter Cohort Study
Creators: name: Juday, Timothy
name: Moore, Richard D.
name: Uy, Jonathan
name: Sterling, Timothy R.
name: Eron, Joseph J.
name: Napravnik, Sonia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Data on the effectiveness of second-line combination antiretroviral therapy (cART) are limited. We evaluated virologic outcomes of second cART in a multicenter cohort collaboration. The study population initiated first and second modern cART between 1996 and 2010. The second cART required a switch in at least the anchor agent of first cART. We evaluated time to virologic failure of second cART and factors associated with greater risk of failure using multivariable Cox proportional hazards models. Of 488 patients who switched to second-line cART, 67% were black and 32% were women. The median HIV-1 RNA at second cART initiation was 9,565 copies/ml [interquartile range (IQR); 123, 94,108]. The time to virologic failure of second cART was longer if HIV-1 RNA was undetectable at switch (p=0.001), although 12% and 17% of patients with undetectable and detectable HIV-1 RNA experienced virologic failure within 6 months of second cART initiation, respectively. A lower CD4 cell count at second cART initiation was associated with a greater risk of virologic failure. Failure rates decreased in more recent calendar years [adjusted relative hazard of 0.40 comparing 2008 to 2010 with 1996 to 1998 (95% confidence interval; 0.15, 1.00)]; however, type of anchor agent was not associated with failure. In conclusion, virologic failure of second cART was less likely if patients switched with undetectable HIV-1 RNA, although risk of early failure was similar. The effectiveness of second cART regimens improved over calendar time and was independent of the anchor agent in the regimen.
Causality analysis of large-scale structures in the flow around a wall-mounted square cylinder
Creators: name: Martínez-Sánchez, Álvaro
name: López, Esteban
name: Clainche, Soledad Le
name: Lozano-Durán, Adrián
name: Srivastava, Ankit
name: Vinuesa, Ricardo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The aim of this work is to analyse the formation mechanisms of large-scale coherent structures in the flow around a wall-mounted square cylinder, due to their impact on pollutant transport within cities. To this end, we assess causal relations between the modes of a reduced-order model obtained by applying proper-orthogonal decomposition to high-fidelity-simulation data of the flow case under study. The causal relations are identified using conditional transfer entropy, which is an information-theoretical quantity that estimates the amount of information contained in the past of one variable about another. This allows for an understanding of the origins and evolution of different phenomena in the flow, with the aim of identifying the modes responsible for the formation of the main vortical structures. Our approach unveils that vortex-breaker modes are the most causal modes, in particular, over higher-order modes, and no significant causal relationships were found for vortex-generator modes. We validate this technique by determining the causal relations present in the nine-equation model of near-wall turbulence developed by Moehlis et al. (New J. Phys, vol. 6, 2004, p. 56), which are in good agreement with literature results for turbulent channel flows.
description: 19 pages, 10 figures
Additional file 1 of A multi-Kalman filter-based approach for decoding arm kinematics from EMG recordings
Creators: name: ElMohandes, Hend
name: Eldawlatly, Seif
name: Audí, Josep Marcel Cardona
name: Ruff, Roman
name: Hoffmann, Klaus-Peter
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1. Supplementary Performance Analysis and Comparison
The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions
Creators: name: Ma, Jun
name: Xie, Ronald
name: Ayyadhury, Shamini
name: Ge, Cheng
name: Gupta, Anubha
name: Gupta, Ritu
name: Gu, Song
name: Zhang, Yao
name: Lee, Gihun
name: Kim, Joonkee
name: Lou, Wei
name: Li, Haofeng
name: Upschulte, Eric
name: Dickscheid, Timo
name: de Almeida, José Guilherme
name: Wang, Yixin
name: Han, Lin
name: Yang, Xin
name: Labagnara, Marco
name: Rahi, Sahand Jamal
name: Kempster, Carly
name: Pollitt, Alice
name: Espinosa, Leon
name: Mignot, Tâm
name: Middeke, Jan Moritz
name: Eckardt, Jan-Niklas
name: Li, Wangkai
name: Li, Zhaoyang
name: Cai, Xiaochen
name: Bai, Bizhe
name: Greenwald, Noah F.
name: Van Valen, David
name: Weisbart, Erin
name: Cimini, Beth A.
name: Li, Zhuoshi
name: Zuo, Chao
name: Brück, Oscar
name: Bader, Gary D.
name: Wang, Bo
Publisher: name: Forschungzentrum Jülich
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: arxiv (2023). doi:10.48550/arXiv.2308.05864
description: Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyperparameters in different experimental settings. Here, we present a multi-modality cell segmentation benchmark, comprising over 1500 labeled images derived from more than 50 diverse biological experiments. The top participants developed a Transformer-based deep-learning algorithm that not only exceeds existing methods, but can also be applied to diverse microscopy images across imaging platforms and tissue types without manual parameter adjustments. This benchmark and the improved algorithm offer promising avenues for more accurate and versatile cell analysis in microscopy imaging.
description: Published by arXiv
Newton versus Coulomb for Kaluza-Klein modes
Creators: name: Benakli, Karim
name: Branchina, Carlo
name: Lafforgue-Marmet, Gaëtan
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider a set of elementary compactifications of $D+1$ to $D$ spacetime dimensions on a circle: first for pure general relativity, then in the presence of a scalar field, first free then with a non minimal coupling to the Ricci scalar, and finally in the presence of gauge bosons. We compute the tree-level amplitudes in order to compare some gravitational and non-gravitational amplitudes. This allows us to recover the known constraints of the $U(1)$, dilatonic and scalar Weak Gravity Conjectures in some cases, and to show the interplay of the different interactions. We study the KK modes pair-production in different dimensions. We also discuss the contribution to some of these amplitudes of the non-minimal coupling in higher dimensions for scalar fields to the Ricci scalar.
description: 35 pages, 7 figures. One typo in an equation corrected
Exact ZF Analysis and Computer-Algebra-Aided Evaluation in Rank-1 LoS Rician Fading
Creators: name: Siriteanu, Constantin
name: Takemura, Akimichi
name: Koutschan, Christoph
name: Kuriki, Satoshi
name: Richards, Donald St. P.
name: Shin, Hyundong
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We study zero-forcing detection (ZF) for multiple-input/multiple-output (MIMO) spatial multiplexing under transmit-correlated Rician fading for an N_R X N_T channel matrix with rank-1 line-of-sight (LoS) component. By using matrix transformations and multivariate statistics, our exact analysis yields the signal-to-noise ratio moment generating function (m.g.f.) as an infinite series of gamma distribution m.g.f.'s and analogous series for ZF performance measures, e.g., outage probability and ergodic capacity. However, their numerical convergence is inherently problematic with increasing Rician K-factor, N_R , and N_T. We circumvent this limitation as follows. First, we derive differential equations satisfied by the performance measures with a novel automated approach employing a computer-algebra tool which implements Groebner basis computation and creative telescoping. These differential equations are then solved with the holonomic gradient method (HGM) from initial conditions computed with the infinite series. We demonstrate that HGM yields more reliable performance evaluation than by infinite series alone and more expeditious than by simulation, for realistic values of K , and even for N_R and N_T relevant to large MIMO systems. We envision extending the proposed approaches for exact analysis and reliable evaluation to more general Rician fading and other transceiver methods.
description: Accepted for publication by the IEEE Transactions on Wireless Communications, on April 7th, 2016; this is the final revision before publication
(100978) Charles Egglestone
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Complex radiological diagnosis of osteonecrosis in patients taking desomorphine in the pre- and postoperative periods
Creators: name: Babkova, Anna
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Bones
subject: Head and neck
subject: Musculoskeletal bone
subject: CT-High Resolution
subject: Conventional radiography
subject: Cone beam CT
subject: Computer Applications-3D
subject: Computer Applications-Detection, diagnosis
subject: Experimental investigations
subject: Drugs / Reactions
subject: Toxicity

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Unfortunately there is a tendency to use cheap toxic synthetic drugs manufactured in the home, such as desomorphine, pervitine, meth and others substances. Drug addiction is one of the most serious social problems in all over the world. Atypical jaw...