title: ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð²Ð»Ð¸ÑÐ½Ð¸Ñ Ð¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ½Ð¾Ð¹ Ð¼Ð°ÑÑÐ¸ÑÑ Ð½Ð° ÐºÐ¸Ð½ÐµÑÐ¸ÐºÑ Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÑ ÑÐ²ÑÐ·ÑÐ²Ð°Ð½Ð¸Ñ ÑÐµÐ»ÐµÐ²Ð¾Ð¹ Ð¼Ð¾Ð»ÐµÐºÑÐ»Ñ Ð³Ð»ÑÐºÐ¾Ð·Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Studying influence of imprinting of a polymer matrix on the kinetics and dynamics binding of the target glucose molecule
Creators: name: ÐÐ°Ð½ÑÑÐ°, ÐÐ½Ð°ÑÑÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: Ð³ÐµÐ¼Ð¾ÑÐ¾ÑÐ±ÐµÐ½ÑÑ
Ð³ÐµÐ¼Ð¾ÑÐ¾ÑÐ±ÑÐ¸Ñ
Ð³Ð»ÑÐºÐ¾Ð·Ð°
Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ° ÑÐ¾ÑÐ±ÑÐ¸Ð¸
Ð¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸Ð½Ð³
ÐºÐ¸Ð½ÐµÑÐ¸ÐºÐ° ÑÐ¾ÑÐ±ÑÐ¸Ð¸
Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÑ
ÑÐ°Ñ Ð°ÑÐ½ÑÐ¹ Ð´Ð¸Ð°Ð±ÐµÑ
ÑÑÐ¸Ð»ÐµÐ½Ð³Ð»Ð¸ÐºÐ¾Ð»Ñ Ð´Ð¸Ð¼ÐµÑÐ°ÐºÑÐ¸Ð»Ð°Ñ
hemosorbents
hemosorption
glucose
sorption dynamics
imprinting
sorption kinetics
polymers
diabetes mellitus
ethylene glycol dimethacrylate

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ¸Ð¹ ÐºÐ¸Ð½ÐµÑÐ¸ÐºÐ¸ Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ ÑÐ¾ÑÐ±ÑÐ¸Ð¸ Ð³Ð»ÑÐºÐ¾Ð·Ñ Ð¼ÐµÐ¶Ð´Ñ Ð¼Ð¾Ð»ÐµÐºÑÐ»ÑÑÐ½Ð¾ Ð¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼ Ð¸ Ð½ÐµÐ¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼ Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ°Ð¼Ð¸. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ ÑÐ°Ð±Ð¾ÑÑ: 1. ÐÐ·ÑÑÐµÐ½Ð¸Ðµ Ð²Ð»Ð¸ÑÐ½Ð¸Ñ ÑÐ°Ð·Ð¼ÐµÑÐ° Ð³ÑÐ°Ð½ÑÐ» Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð½Ð° ÐºÐ¸Ð½ÐµÑÐ¸ÐºÑ ÑÐ¾ÑÐ±ÑÐ¸Ð¸ Ð³Ð»ÑÐºÐ¾Ð·Ñ. 2. ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð²Ð»Ð¸ÑÐ½Ð¸Ñ Ð¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ½Ð¾Ð¹ Ð¼Ð°ÑÑÐ¸ÑÑ Ð½Ð° ÑÐ°ÑÐ°ÐºÑÐµÑ Ð´Ð¸ÑÑÑÐ·Ð¸Ð¸ Ð¼Ð¾Ð»ÐµÐºÑÐ» Ð³Ð»ÑÐºÐ¾Ð·Ñ. 3. ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ ÑÐµÐ¶Ð¸Ð¼Ð¾Ð² ÑÐ¾ÑÐ±ÑÐ¸Ð¸ Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¾Ð² Ð² Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐ»Ð¾Ð²Ð¸ÑÑ. 4. ÐÑÑÐ²Ð»ÐµÐ½Ð¸Ðµ Ð¾Ð¿ÑÐ¸Ð¼Ð°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»ÑÐ¼ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ Ð¸ ÐºÐ¸Ð½ÐµÑÐ¸ÐºÐ¸ ÑÐ¾ÑÐ±ÑÐ¸Ð¸ Ð³Ð»ÑÐºÐ¾Ð·Ñ ÑÐ¾ÑÐ±ÐµÐ½ÑÐ° Ð´Ð»Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð² ÑÑÐ¾Ð¼Ð°ÑÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¾ÑÐµÑÑÐ°Ñ. Ð Ð°Ð±Ð¾ÑÐ° Ð¿ÑÐ¾ÑÐ¾Ð´Ð¸Ð»Ð° Ð² ÐÐÐ¡ Ð ÐÐ, Ð³Ð´Ðµ Ð±ÑÐ»Ð¸ ÑÐ¸Ð½ÑÐµÐ·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð¸ÑÑÐ»ÐµÐ´ÑÐµÐ¼ÑÐµ Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÑ Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ ÐºÐ¸Ð½ÐµÑÐ¸ÐºÐ° Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ° ÑÐ¾ÑÐ±ÑÐ¸Ð¸ Ð³Ð»ÑÐºÐ¾Ð·Ñ. Ð¡ Ð¿Ð¾Ð¼Ð¾ÑÑÑ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ OriginProLab Ð±ÑÐ»Ð¸ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ñ ÐºÐ¸Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ ÐºÑÐ¸Ð²ÑÐµ ÑÐ¾ÑÐ±ÑÐ¸Ð¸ ÑÐµÐ»ÐµÐ²Ð¾Ð³Ð¾ ÐºÐ¾Ð¼Ð¿Ð¾Ð½ÐµÐ½ÑÐ°. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð±ÑÐ»Ð° ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð° ÑÑÐ°ÐºÑÐ¸Ñ Ð¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ°, Ð¾Ð±Ð»Ð°Ð´Ð°ÑÑÐ°Ñ Ð»ÑÑÑÐ¸Ð¼ Ð²ÑÐµÐ¼ÐµÐ½ÐµÐ¼ Ð½Ð°ÑÑÑÐµÐ½Ð¸Ñ Ð¸ Ð²ÐºÐ»Ð°Ð´Ð¾Ð¼ ÑÐ¿ÐµÑÐ¸ÑÐ¸ÑÐ½Ð¾Ð³Ð¾ ÑÐ²ÑÐ·ÑÐ²Ð°Ð½Ð¸Ñ Ð¼Ð¾Ð»ÐµÐºÑÐ» Ð³Ð»ÑÐºÐ¾Ð·Ñ Ñ Ð¸Ð¼Ð¿ÑÐ¸Ð½Ñ-ÑÐ°Ð¹ÑÐ°Ð¼Ð¸. ÐÐ° Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð½ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ð² ÐÐÐ¡ Ð ÐÐ Ð±ÑÐ»Ð¾ Ð²ÑÑÐ²Ð»ÐµÐ½Ð¾, ÑÑÐ¾ Ð¸Ð¼Ð¿ÑÐ¸Ð½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÐ°Ð±Ð»Ð¾Ð½Ð½ÑÑ Ð¼Ð¾Ð»ÐµÐºÑÐ» Ð³Ð»ÑÐºÐ¾Ð·Ñ Ð² Ð¿ÑÐµÐ´Ð¿Ð¾Ð»Ð¸Ð¼ÐµÑÐ¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¹ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ Ð·Ð½Ð°ÑÐ¸ÑÐµÐ»ÑÐ½Ð¾ Ð¿Ð¾Ð²Ð»Ð¸ÑÐ»Ð¾ Ð½Ð° ÑÐ°ÑÐ°ÐºÑÐµÑ ÐºÐ¸Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¸Ñ ÐºÑÐ¸Ð²ÑÑ Ð¸ Ð¸Ð·Ð¼ÐµÐ½Ð¸Ð»Ð¾ ÑÐµÐ¶Ð¸Ð¼ ÑÐ¾ÑÐ±ÑÐ¸Ð¸ Ð² Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐ»Ð¾Ð²Ð¸ÑÑ.
description: The given work is devoted to the study of differences kinetics and dynamics of glucose sorption between molecularly imprinted and non-imprinted polymers. The research set the following goals: 1. Studying the effect of polymer granule size on the kinetics of glucose sorption. 2. Analysis of the influence of imprinting of a polymer matrix on the character of diffusion of glucose molecules. 3. Determination of sorption modes under dynamic conditions. 4. Identification of the optimal sorbent in terms of dynamics and kinetics of glucose sorption for further use in chromatographic processes. The work was fulfilled in IMC RAS, where were synthesized polymers and held kinetics and dynamics of glucose sorption. Kinetic and dynamic curves of the sorption of the target component were constructed using the OriginProLab software. As a result, the fraction of the imprinted polymer was found to have the best saturation time and the contribution of specific binding of glucose molecules to imprint sites. Based on the research at IMC RAS it was discovered that imprinting of template glucose molecules into the prepolymerization complex significantly influenced on the kinetic curves and changed the sorption mode under dynamic conditions.