cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Trafikplan for Region Sjælland
Creators: name: Richter, Lars
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2009

description: Trafikplanen evaluerer den nuværende regionale trafik – der er en viderførelse af den hidtidige trafik i hhv STS (Storstøms Amt), VT (Vestsjællands Amt) og HUR (det tidligere Roskilde Amt) , og opstiller en plan for den fremtidige regionale trafik i Region Sjælland. Som andre steder i landet lægges der op til ændringer ift. hvilke trafikale opgaver der skal løses af regionen – og hvilke der skal overlades til kommunerne. Der er flere vinkler i emnet; Dels selve trafikplanen, hvor der ligger en konkret plan for den fremtidige regionale betjening. Men også den efterfølgende proces og diskussionen med kommunerne som løber af staben pt. er interessant. I følge tidsplanen behandles trafikplanen endeligt af regionen i maj, så også den politiske beslutning vil være kendt til august. Planen er udarbejdet på baggrund af analyser af den eksisterende trafik, tidligere rapporter om hvad der skal til for at få flere passagerer i den kollektive trafik samt en gennemgang af pendlingstal mhp. at fastslå hvilke relationer der er relevante ift. den regionale trafik. Resultat af arbejdet er selve planen for den fremtidige regionale trafik. Planen lægger op til en offentsiv satsning på at få flere passagerer i den kollektive trafik ved hjælp af centrale elementer som høj frekvens, langt driftsdøgn, sammenhæng mellem bus og bane samt et hurtigt og enkelt net.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2009): Proceedings from the Annual Transport Conference at Aalborg University
Bilrejseplanen
Creators: name: Woolridge, Birgitte Lomholt
name: Dyreborg, Sine
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2009

description: Rejseplanen og Vejdirektoratet har besluttet at implementere en rejseplanlægger, hvor oplysninger om kollektive rejser og bilrejser kombineres i samme rejseplanlægger. Formålet er at give bilister bedre information om deres valgmuligheder og samtidig motivere bilister til at bruge kollektiv transport ved at vise, at det nogen gange er hurtigere end at tage bilen, idet planlæggeren viser realistiske rejsetider for bilrejsen. Samtidig vises også pris og CO2 belastning for rejserne. Efter gennemførelsen af et tilfredsstillende pilotforsøg i 2008 blev det besluttet at lave en fuld implementering, som forventes i fuld drift i løbet af efteråret 2009.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2009): Proceedings from the Annual Transport Conference at Aalborg University
Tilgængelighedsanalyser og servicemål i kollektiv trafik – en kombination af GIS-værktøjer og automatiserede opslag i Rejseplanen.dk
Creators: name: Høj, Jakob
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2009

description: Efter strukturreformen har kommunerne fået ansvaret for at definere serviceniveauet i den lokale kollektive bustransport, som følge af at det fulde finansieringsansvar efter 1.1 2007 er overgået til kommunerne. Det betyder, at mange kommuner som led i busplanlægningen har behov for på systematisk vis at få kortlagt og analyseret det nuværende serviceniveau i den kollektive transport. I mange af sammenlægningskommunerne kan der være markante forskelle i det serviceniveau, som har været gældende inden for de gamle kommunegrænser. En systematisk kortlægning af serviceniveauerne kan med fordel udføres ved hjælp af GIS- værktøjer i kombination med automatiserede opslag i Rejseplanen.dk og udtræk fra de kommunale registre om boliger, arbejdspladser og byfunktioner. I denne artikel beskrives metoder, som kan anvendes i analyserne af tilgængelighed og serviceniveau i den kollektive trafik. Der er vist eksempler på, hvordan analyserne kan føde ind i arbejdet med at opstille servicemål og evaluere forskellige kollektive trafiknet.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2009): Proceedings from the Annual Transport Conference at Aalborg University
EST-SSR analysis and cross-species transferability study in Lavandula
Creators: name: Adal, Ayelign M.
name: Demissie, Zerihun Abebe
name: Mahmoud, Soheil S.
Publisher: name: The University of British Columbia
Year: 2019

description: The genus Lavandula comprises of several economically important lavender species that are mainly cultivated worldwide for essential oil production. Identification of lavender species and their cultivars has been a huge bottleneck in lavender industries due to lack of appropriate identification mechanisms. Recent advances in modern technologies would help to address these identification issues through development of potential molecular markers, including simple sequence repeats (SSRs). SSRs can be developed from specific species, and can be potentially used for related species, which lack the source sequences to develop species-specific SSRs. Here, we describe the guidelines and steps of identifying and analyzing SSRs from expressed sequence tag (EST) sequences of lavender species. We also detail the validation procedures of selected EST-SSRs in distinguishing source (donor) species as well as related species.
Incitamentsprogram for by- og metrobusserne i Aalborg
Creators: name: Jensen, Susan Bundgaard
Publisher: name: Proceedings from the Annual Transport Conference at Aalborg University
Year: 2009

description: NT og Aalborg Kommune har indgået en historisk aftale med City-Trafik og Arriva om et incitamentsprogram for by- og metrobusserne i Aalborg. Programmet trådte i kraft ved køreplanskiftet 29. juni 2008, hvor det erstattede den hidtidige bonusmodel. På by- og metrobuslinierne i Aalborg kører ca. 100 busser, og der transporteres årligt omkring 14,7 mio passagerer rundt. Omsætningen ligger på 150 mio. kr. Passagertallet i by- og metrobusserne er faldet markant de seneste år. Samtidig har kvalitetsmålingerne generelt vist så utilfredsstillende en kvalitet, at der tidligere stort set ikke er udbetalt bonus til by- og metrobusserne. Sammen med chauffører og entreprenører besluttede NT at ændre fokus, så det igen bliver muligt at opnå bonus ved at levere en god service, som kan tiltrække flere kunder. Incitamentsprogrammet belønner entreprenører og chauffører, der skaffer flere og mere tilfredse kunder i busserne. Når aftalen betegnes som historisk, er det fordi, Aalborg Kommune er den første i landet, der har indført et incitamentsprogram for samtlige by- og metrobussser.
description: Proceedings from the Annual Transport Conference at Aalborg University, Vol. 1 No. 1 (2009): Proceedings from the Annual Transport Conference at Aalborg University
Effectiveness of relaxation training for anxiety and depression in family caregivers of long-term stroke survivors.
Creators: name: Csecs, Jenny
Publisher: name: University of Surrey
Year: 2020
Subjects: stroke caregivers
anxiety
depression
relaxation training

description: Objectives: Anxiety and depression are commonly experienced by caregivers of stroke survivors. However, interventions which directly target mood are limited and no recommendations for treatment of anxiety and depression of caregivers of stroke survivors currently exist. This study aimed to assess the effectiveness of self-help relaxation training for anxiety, depression and coping in caregivers of stroke survivors. Additional aims were to explore whether participants followed the proposed structure of the relaxation training and whether their experience replicated effects other populations have reported in the literature in relation to using relaxation training. Method: This mixed methods study adopted a repeated measures within-participant design assessing anxiety, depression and coping at three time points (Pre-1, Pre-2 and Post; N = 18 caregivers of stroke survivors). Post-intervention, semi-structured interview data were also collected and analysed using deductive thematic analysis. Results: Quantitative outcome measures showed significant improvement post-intervention in anxiety, depression and coping in relation to managing stress. Managing Events/Problem-solving and Managing Perceptions/Meanings coping scores showed no significant change post-intervention. Qualitative data supported the quantitative findings, and suggested that participants generally followed the proposed structure of the relaxation training and reported similar effects as found in the literature. Conclusions: This study supports the use of self-help relaxation training for caregivers of stroke survivors in terms of relieving anxiety and depression. Follow-up research is required to assess whether the effects are maintained and to determine whether there are factors which could influence the likelihood of change.
Multiphysics modelling and measurements of microwave-frequency power transistors.
Creators: name: Gillespie, Sean J.
Publisher: name: University of Surrey
Year: 2020

description: The introduction of next generation mobile systems and alternative applications demands significant improvement in efficiency and linearity of the power amplifier. It is essential to understand the limitations inherent to the power transistor, and improve it for emerging applications. The package containing the power transistor is built up of various components; MOS capacitors, bond wire arrays and ESD protection circuitry common in commercial power transistors in addition to the semiconductor transistor die. The objectives of this work are to develop multiphysics modelling components which are needed for CAD-based design optimisation. An electrothermal bond wire array model is proposed which combines the electrical and thermal characteristics at high-frequency, reproducing the non-uniform distribution seen in measurements. The model returns the temperature distribution over 2000-times faster, in a fraction of a second, compared to an equivalent 3D multiphysics simulation which takes at least 23 minutes, making it well suited to circuit modelling for CAD-design and optimisation. Fundamentally, the foundations of the power transistor is the semiconductor technology that the package holds. Extraction of compact transistor models is time consuming, requiring a multitude of measurement steps and specialised equipment. Behavioural modelling techniques simplify the measurement extraction procedure, while conserving the accuracy and convergence needed for circuit modelling. A primary limiting factor of the X-parameter behavioural model is that it lacks thermal memory effects that are prevalent in most applicable transistor technologies. This work extends the extraction of X-parameters to include dynamic thermal memory effects. Thermal hysteresis is demonstrated and shown to introduce spectral asymmetry during simulations using two-tone and QAM-16 modulation stimulus. Furthermore, distributed multiphysics modelling techniques co-simulate electromagnetics, thermodynamics and semiconductor device physics - the coupled solution providing enhanced insight into the performance and limitations of the transistor compared to lumped modelling approaches. A distributed electrothermal model was developed which enables significant design improvements by optimisation of the thermal and electrical layouts. This is demonstrated at 28~GHz for a GaN pHEMT transistor where a 12% increase in linear output power and 54% increase in PAE is achieved relative to the peak efficiency of the transistor (24%). The multiphysics modelling components developed in this work aim to improve power transistors for next generation mobile systems and applications requiring the efficient application of high-power microwaves.
The association between rumination and psychological and physical health outcomes in those diagnosed with cancer
Creators: name: Beck, Sarah
Publisher: name: University of Surrey
Year: 2023

description: Rumination is defined as a type of perseverative cognition involving cyclical and selffocused
description: thoughts about an individual’s problems and concerns. Increasing research has
description: explored the role of rumination in adjustment after a cancer diagnosis. This multi-method
description: thesis aimed to extend the literature by exploring the association between different styles of
description: rumination and psychological and physical health in those diagnosed with cancer.

description:

description: A systematic review and four empirical studies were conducted. The overarching
description: finding of the systematic review suggested that the style of rumination was important when
description: considering its association with distress after a cancer diagnosis. Study 1 and 2 extended this
description: finding to explore the different styles of rumination alongside negative and positive
description: psychological outcomes respectively. Results highlighted brooding to be associated with
description: depression and anxiety six months later, and intrusive rumination associated with anxiety.
description: Instrumental rumination was not associated with distress. Brooding was associated with
description: depression and anxiety through different mechanisms. For adaptive outcomes, post-traumatic
description: growth was associated with later instrumental rumination and was not associated with
description: brooding or intrusive rumination. Results from Study 3 showed brooding to also be
description: associated with self-rated health measures (somatisation and health-related quality of life) six
description: months later. Negative affect partially mediated the association between brooding and
description: somatisation. Finally, a qualitative exploration (Study 4) of the experience of rumination after
description: a cancer diagnosis found five main themes. Rumination stems from perceived discrepancy, is
description: multifaceted, involves positive and negative beliefs, is associated with various negative and
description: positive outcomes, and that rumination changes over time.

description:

description: In summary, the results of this thesis provide novel evidence of the experience of
description: rumination and psychological and physical health in those diagnosed with cancer.
description: Rumination was associated with psychological and physical health measures, particularly
description: brooding which was associated with depression anxiety, and somatisation and poorer
description: health-related quality of life.
Meine Heimat – Euer Krieg
Creators: name: Geske-Scholz, Brigitte
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Buchbesprechung von: Saovory Kim Sam, Meine Heimat - Euer Krieg. Kindheit in Kambodscha. TRIGA – Der Verlag, 2008, ISBN 978-3-89774-609-1.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Mama Maly – Der Kampf gegen die Kinderprostitution
Creators: name: Schott, Christina
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Ein Portrait der Frau, die in Kambodscha zum Symbol für den Kampf gegen Kinderprostitution wurde.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Exploring student views on classroom-based interventions on DSH.
Creators: name: Webster, Sophie
Publisher: name: University of Surrey
Year: 2020

description: Background: Due to rising in rates in deliberate self-harm (DSH) and increasing pressure on NHS services, the government is looking to schools to provide a front-line response. Previous adolescents have indicated that more information on distress and alternative ways of coping would be helpful. However, teachers have raised concerns that talking about DSH in schools could lead to an increase in prevalence i.e. contagion. Therefore, this study aimed to explore student’s views of a classroom-based intervention on DSH and any potential consequences resulting from this teaching. It hoped to ascertain whether pupils had similar concerns to teachers around contagion following exposure to an intervention. Method: Sixty-one students in England (years 7-10) participated in 11 focus groups which were conducted in three secondary schools. They discussed their thoughts on having teaching on DSH and what the potential consequences of any teaching might be. Only one of the schools already provided teaching on DSH in the classroom and wider school environments, and their ideas appeared to be informed their experiences of this teaching. Results: Two themes emerged from the data which were ‘Should we talk openly about DSH?’ and ‘How to talk to openly about DSH’. Conclusions: The majority of the students within the focus groups expressed a desire to learn about DSH in lessons, with a few expressing concerns about the potential for contagion. All groups discussed ways to reduce the likelihood of contagion occurring. Most felt teaching would have a protective element and reduce DSH. The results indicate teaching on DSH in an open manner in the classroom is warranted, although further research measuring contagion following any intervention would add to the evidence.
Caducidad de la acción de reparación directa derivada de asuntos de lesa humanidad en Colombia
Creators: name: Chacón Monroy, Paula Andrea
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Crimenes de lesa humanidad
subject: Derechos humanos - Aspectos jurídico
subject: Sentencia - Legislación
subject: Acción de reparación directa
subject: Medio de control
subject: Caducidad
subject: Desaparición forzada
subject: Desplazamiento forzado

description: El presente trabajo busca analizar la forma en cómo funciona la figura de la caducidad respecto de la acción de reparación directa en el ordenamiento jurídico colombiano, -en especial en el caso de la desaparición forzada, desplazamiento forzado y lesa humanidad-, antes y después de la sentencia de unificación del 29 de enero de 2020 del Consejo de Estado. Para así realizar una valoración respecto de los argumentos esgrimidos por la corporación y los efectos que la misma tendrá para las víctimas del conflicto armado y el Estado colombiano en el ámbito internacional.
description: The present work seeks to analyze the way in which the figure of expiry works with respect to the action of direct reparation in the Colombian legal system, -especially in the case of forced disappearance, forced displacement and against humanity-, before and after the unification judgment of January 29, 2020 of the Council of State. In order to carry out an assessment regarding the arguments put forward by the state corporation and the effects that it will have for the victims of the armed conflict and the Colombian State in the international arena.
Observation of heteronuclear Feshbach resonances in a mixture of bosons and fermions
Creators: name: Inouye, Shin
name: Goldwin, J.
name: Olsen, M. L.
name: Ticknor, C.
name: Bohn, John L.
name: Jin, Deborah S.
Publisher: name: Swinburne
Year: 2024

description: Three magnetic-field induced interspecies Feshbach resonances were observed in collisions between bosonic 87Rb and fermionic 40K atoms in their absolute ground states. At the resonance positions of 492, 512, and 543±2 G, strong inelastic loss from an optically trapped mixture was observed. The two higher-field resonances were found to have s wave character, while the narrow feature at 492 G represented a p-wave resonance. The results show that changing C6 has a negligible effect on the error bars.
Optimal Design of Energy Storage System for Peak-Shaving in Industrial Production
Creators: name: Li, Lixin
name: Starosta, Anna Sina
name: Schwarz, Bernhard
name: Munzke, Nina
name: Strehle, Hanns-Martin
name: Richter, Mark
name: Hiller, Marc
Publisher: name: VDE Verlag
Year: 2023
Subjects: energy storage technology
industrial production
mixed-integer linear programming
peak-shaving

description: Energy storage systems (ESS) offer a wide range of applications in industrial production, with the potential to significantly reduce electricity power costs through peak-shaving, particularly in Germany. This paper proposes a methodology for designing ESSs specifically for industrial peak shaving from a techno-economic perspective. The proposed approach utilizes mixed-integer linear programming (MILP) to calculate the minimum annualized total operating costs, compares various energy storage technologies (EST) to determine the optimal solution, and performs sensitivity analysis to identify critical impact factors on the optimization problem. A case study is implemented with real-world data. The results indicate that connecting a 38.4 kW/38.4 kWh lithium-ion (Li-ion) battery energy storage system (BESS) to the example factory delivers the greatest economic benefit compared to the other three storage technologies. This results in a total cost saving of 980 €/a and a peak power reduction of 33.8 kW. Additionally, a lookup table is provided to assist the factory in selecting the optimal Li-ion BESS available in the market. © VDE VERLAG GMBH Berlin Offenbach.
Spiegel der Frau – Medien als Sprachrohr der Frauen in Kambodscha
Creators: name: Scheiermann, Anika
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Die Ungleichheit zwischen Männern und Frauen ist in Kambodscha immer noch erschreckend groß. Gewalt gegen Frauen sowie Frauenhandel sind weit verbreitet. Um hier etwas zu verbessern, ist Aufklärungsarbeit über die Rechte der Frauen äußerst wichtig. Welche Kommunikationschance für Frauen bieten Medien dabei eigentlich?
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Aftermath of Mountain Pine Beetle Outbreak in British Columbia: Stand Dynamics, Management Response and Ecosystem Resilience
Creators: name: Dhar, Amalesh
name: Parrott, Lael
name: Hawkins, Christopher D.B.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: The mountain pine beetle (Dendroctonus ponderosae Hopkins) (MPB) has infested and killed millions of hectares of lodgepole pine (Pinus contorta var. latifolia Engelm) forests in British Columbia, Canada, over the past decade. It is now spreading out of its native range into the Canadian boreal forest, with unknown social, economic and ecological consequences. This review explores the ramifications of the MPB epidemic with respect to mid-term timber supply, forest growth, structure and composition, vegetation diversity, forest fire, climate change, and ecosystem resilience. Research confirms that, in British Columbia, all of these variables are more significantly impacted when salvage logging is used as management response to the outbreak. We conclude that appropriate management in response to MPB is essential to ensuring ecologically resilient future forests and reliable mid-term timber supplies for affected human communities. We highlight knowledge gaps and avenues for research to advance our understanding in support of sustainable post-disturbance forest management policies in British Columbia and elsewhere.
Machine learning for a finite size correction in periodic coupled cluster theory calculations
Creators: name: Weiler, Laura
name: Mihm, Tina N.
name: Shepherd, James J.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We introduce a straightforward Gaussian process regression (GPR) model for the transition structure factor of metal periodic coupled cluster singles and doubles (CCSD) calculations. This is inspired by the method introduced by Liao and Grüneis for interpolating over the transition structure factor to obtain a finite size correction for CCSD [J. Chem. Phys. 145, 141102 (2016)], and by our own prior work using the transition structure factor to efficiently converge CCSD for metals to the thermodynamic limit [Nat. Comput. Sci. 1, 801 (2021)]. In our CCSD-FS-GPR method to correct for finite size errors, we fit the structure factor to a 1D function in the momentum transfer, $G$. We then integrate over this function by projecting it onto a k-point mesh to obtain comparisons with extrapolated results. Results are shown for lithium, sodium, and the uniform electron gas.
description: 7 pages, 2 figures
The new Labour and Conservative-led governments’ articulation of immigration control policies in Britain : securitization, governmentality and risk 1997-2017.
Creators: name: Acik, Ahmet
Publisher: name: University of Surrey
Year: 2020

description: This thesis analyses the political discourse on immigration control in Britain between 1997 and 2017 and examines why and how the articulations of policies displayed patterns of rupture and continuity between the Conservative-led and the New Labour governments. In particular, it highlights the significance of the critical engagement with both the structure and organization of the articulations within and across texts and their variability and contingency over time. The thesis adopts a multi-perspective framework: Laclau and Mouffe’s (1985, 1987) discourse analysis underpins all the analytical work in this thesis, supplemented by models of securitization, risk and governmentality. The analysis of political discourses reveals that the Conservative-led governments’ articulations displayed patterns of rupture rather than continuity with those of the preceding New Labour governments. The empirical data reveals that while the articulated discourses were used in a variety of ways simultaneously, the articulation by the first and second New Labour governments was generally exemplified by the evolution of a discourse of opportunity, informed by an opportunity-linked risk logic which clearly and consistently embodied values and beliefs consistent with liberal orientations. The discourse of problematization which was articulated by the third New Labour government hovered between opportunity and threat and brought them together as two dependencies that offered a reconfigured discourse which modified the two discourses as opposite forces through strategic readjustment of the heterogeneous elements. The Conservative-led governments articulated a discourse of threat which was often used to frame quite specific fears as a way to generate constructed meanings in which threat-linked logic informed the articulations. The findings highlight the variability and contingency of the articulations in which the discourses evolved, became intertwined and replaced one another. Moreover, the thesis interrogates the claim that threat and problematization-linked logics represent the unique rationalities of these articulations and puts forward an alternative conceptualization of an advanced understanding of risk.
Сфираль как геометрическая модель монистического всеединства - сопоставление с теорией И.Э. Булыженкова
Creators: name: Басаргин, Олег Сергеевич
Publisher: name: Zenodo
Year: 2025

description: Статья предлагает сопоставление эталонной геометрии структуры Сфирали с монистической физикой нелокального всеединства пространства-материи, развитой в трудах И.Э. Булыженкова. Показано, что Сфираль совмещает геометрию формы и топологию нелокальной связности в устойчивом объекте, способном к фрактальной самоорганизации. Построен мост между формой и физикой как одной онтологии всеединства.
Nachrichten
Creators: name: Timmann, Anke
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Nachrichten aus der Region.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Investigating the role of adrenergic signalling in T-cell senescence
Creators: name: Morgan, Phillip
Publisher: name: University of Surrey
Year: 2023

description: Immunosenescence, described as the loss of normal immune function with age is a risk-factor culpable in age-related disease, susceptibility to infection, and reduced vaccine response. Increased immunosenescence is linked with the accumulation of TEMRA cells. Interestingly, these cells express increased β2-Adrenergic Receptor (β2AR) gene and protein compared to other T-cells. Previous work in the murine model found β2AR-stimulation induced p38-signalling, reactive oxygen species (ROS) generation and DNA damage, which are all senescent characteristics of TEMRA-cells. Furthermore, β2AR-stimulation decreases T-cell functionality including proliferation and IFNγ-production. Whether β2AR-signalling plays a causative role in the TEMRA senescence phenotype and/or reduced cellular functionality is not known. The overall aim of this PhD project is to explore the link between the increased β2AR expression observed with greater differentiation of human T-cells, and the significance of this relationship within the context of increased senescent characteristics exhibited by TEMRA cells.

description:

description: Primary human CD8+/CD4+ T-cells were subjected to acute and chronic βAR-stimulation protocols, and downstream DNA damage, senescent-related signalling pathways and T-cell functionality were assessed by Flow Cytometry and Western Blotting.

description:

description: Senescent TEMRA cells demonstrated the greatest β2AR-signalling response. The senescence signalling molecules, p-p38 MAPK and ROS, increased proportionally with β2AR expression in T-cells. Furthermore, T-cell functionality (IL-2, TNFα, IFNγ expression and proliferation) was also impaired in T-cells exhibiting greater β2AR expression. Finally, daily adrenergic stimulation of sorted CD8+ T-cells led to increased p-p38, p53, p-p53 and γH2AX (DNA damage) expression accompanied by prolonged cytokine suppression in TEMRA cells, importantly highlighting their susceptibility to adrenergic-induced senescence.

description:

description: These findings demonstrate, for the first time, a molecular link between β2AR-signalling, T-cell senescence phenotype and reduced T-cell immune function. A greater understanding of the relationship between sympathetic nervous system activity, β2AR-stimulation and immunosenescence, may identify future therapeutic (βAR-antagonism) and prophylactic (stress-reduction) interventions aimed at improving the aged immune response.
Schlechtes Karma – Chancen für Behinderte in Laos
Creators: name: Dambon, Svenja
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Epilepsie als Besessenheit des Geistes. Körperliche Beeinträchtigungen als Schande und Schuld der Eltern. Dieser Glaube ist in Laos noch verbreitet. Dennoch gibt es Projekte, welche das Leben von Behinderten in Zukunft erleichtern könnten. Doch können diese auch realisiert werden?
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Nachrichten
Creators: name: Knappe, Eberhard
name: Wünsch, Susanne
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Nachrichten aus der Region.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Exploring perceptions of support staff of underweight in adult service users with learning disabilities: an interpretative phenomenological analysis study.
Creators: name: Godfrey, Nicky
Publisher: name: University of Surrey
Year: 2020

description: Background: Evidence suggests that underweight is associated with health consequences and has a higher prevalence among adults with learning disabilities compared to the general population. This research aimed to explore the perceptions of support staff of underweight in the adults with learning disabilities they support. Method: Eleven support staff from residential learning disabilities services were interviewed. Interpretative phenomenological analysis was used to interpret the data. Results: Three superordinate themes emerged that suggested a sense of uncertainty about supporting underweight residents, including that participants were holding conflicting ideas about underweight and were unsure about the causes and consequences of underweight. Participants perceived underweight in adults with learning disabilities as different from underweight in the general population, including that residents did not understand underweight. All participants described challenges associated with supporting underweight residents, including judgements that they might face and difficulties in encouraging underweight residents to eat. They also identified helpful strategies, including investigating underweight and trying different strategies to find one that was effective for the individual resident, and working as a team. Conclusions: Overall, participants appeared to experience supporting underweight residents as complex and challenging, and fundamentally different from underweight in the general population. This is suggestive of an ‘us’ and ‘them’ approach, with participants’ understanding of causes of residents’ underweight possibly influencing how they responded to it. The challenges and judgements that participants described facing around supporting underweight residents can be seen in the context of underweight appearing to be overshadowed by overweight, in services and in society. Uncertainty and lack of confidence around underweight could be addressed through the development of national practice guidelines for supporting underweight residents, alongside staff training about underweight to promote awareness of it. Further research exploring the perspectives of adults with learning disabilities and of other professionals could helpfully inform such interventions.
Diskriminiert & illegalisiert – Arbeitsmigranten in Vietnam und die Auswirkungen der globalen Wirtschaftskrise
Creators: name: Waibel, Michael
name: Gravert, Andreas
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2019

description: Die weltweite Nachfrageabschwächung als Folge der Krise hat sich auf Vietnam als stark exportabhängiges Land in besonderem Maße durchgeschlagen. Die einsetzenden Massenentlassungen betreffen vor allem Arbeitsmigranten, deren Situation aufgrund problematischer Arbeits- und Wohnbedingungen, sowie unsicherem legalem Status ohnehin als prekär zu bezeichnen ist. Die Autoren fordern die Krise als Chance zu nutzen, Arbeitsmigranten endlich rechtlich anzuerkennen und dabei vor allem das diskriminierende Haushaltsregistrationssystem abzuschaffen.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Integrationsvarianten
Creators: name: Dahm, Bernhard
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Buchbesprechung von: Grit Grigoleit, Integrationsvarianten. Die Hmong in den USA. Bd. 3 der Schriften der Forschungsstelle Grundlagen Kulturwissenschaft, Uni Passau, ISBN 978-3-88849183-2.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Der Papiertiger brüllt – Menschenrechtsschutz in Südostasien
Creators: name: Hesse, Nicole
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Bereits seit 1967 existiert die Association of Southeast Asian Nations, doch erst am 1 5. Dezember 2009 trat die ASEAN-Charta in Kraft.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Voraussetzungen für ein gutes Leben – Einführung zum Thema: Lebenschancen in Südostasien
Creators: name: Beuchling, Olaf
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Hinter dem Begriff »Lebenschancen« verbirgt sich ein normativ, gesellschaftspolitisch und sozialwissenschaftlich grundlegendes Konzept. Auf der allgemeinsten Ebene scheint der Begriff sich selbst zu erklären: Lebenschancen sind das Gegenteil von Todesfällen. Vor die Wahl gestellt, wollen Menschen nicht in Ausweglosigkeit verharren, sondern Chancen ergreifen können.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Inhalt und Impressum
Creators: name: Redaktion, Die
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 3 (2009): 1-2-3, letzte Chance vorbei? Lebenschancen in Südostasien
Evaluating the impact of complex tourism interventions in EU- funded project contexts
Creators: name: Montano, Luigina Jessica
Publisher: name: University of Surrey
Year: 2024

description: This thesis offers insight into three evaluation methods (namely, Theory of Change, Process Tracing, and Most Significant Change) rooted in the concept of complexity social science, and grounded in the theoretical underpinnings of complex realism, the three methods are applied to evaluate the impacts of a sustainable tourism project implemented in six pilot regions under the France-Channel England EU-INTERREG programme. The thesis discusses the value of three qualitative, complexity-aware evaluation methods, implemented in a participatory manner, in aiding the researcher throughout the exploration of the complex role of human agency in change initiatives. A main overall finding of the thesis is that participatory, complexity-aware evaluation methods can encourage multiple layers of leaning (project implementers, beneficiaries and funders) whilst at the same time support a more holistic and positive understanding of accountability which is not solely directed to funders but also at a local policy level and across all stakeholders of an intervention. Findings suggest that for evaluation to move beyond being perceived as a tedious, box-ticking exercise centred on how a funder’s money was spent, there first needs to be a shift in mindset among those commissioning projects and allocating funding.

description:

description: The thesis offers a theoretical and empirical framework that sets the precedent for learning and accountability to be understood as two concepts that go hand in hand in the evaluation process. It is the first study that applies the three methods in tandem, though at different stages of the evaluation, to maximise the benefits of each method, enriching the understanding of what represents impact. The methods discussed across the three studies make explicit the links between the theorised intervention and the mechanisms contributing to change once the intervention is implemented on the ground. The innovative application of participatory, qualitative, complexity-aware evaluation methods to the field of tourism interventions facilitates the exploration of non-linear relationships and feedback loops amongst the actors involved in the implementation of an intervention. In response to an emerging agenda calling for more holistic evaluation methods for sustainability-oriented tourism interventions, the methods explored throughout this thesis illustrate how grounding evaluation methods in theoretical framework of complex realism enhances learning and accountability of tourism policy making a valuable contribution to knowledge in the field of sustainable tourism intervention, particularly in how we evaluate impacts of the latter.
Cardiorespiratory fitness as a predictor of intestinal microbial diversity and distinct metagenomic functions
Creators: name: Estaki, Mehrbod
name: Pither, Jason
name: Baumeister, Peter
name: Little, Jonathan P.
name: Gill, Sandeep K.
name: Ghosh, Sanjoy
name: Ahmadi-Vand, Zahra
name: Marsden, Katelyn R.
name: Gibson, Deanna L.
Publisher: name: BioMed Central
Year: 2016

description: Background: Reduced microbial diversity in human intestines has been implicated in various conditions such as diabetes, colorectal cancer, and inflammatory bowel disease. The role of physical fitness in the context of human intestinal microbiota is currently not known. We used high-throughput sequencing to analyze fecal microbiota of 39 healthy participants with similar age, BMI, and diets but with varying cardiorespiratory fitness levels. Fecal short-chain fatty acids were analyzed using gas chromatography. Results We showed that peak oxygen uptake (VO2peak), the gold standard measure of cardiorespiratory fitness, can account for more than 20 % of the variation in taxonomic richness, after accounting for all other factors, including diet. While VO2peak did not explain variation in beta diversity, it did play a significant role in explaining variation in the microbiomes’ predicted metagenomic functions, aligning positively with genes related to bacterial chemotaxis, motility, and fatty acid biosynthesis. These predicted functions were supported by measured increases in production of fecal butyrate, a short-chain fatty acid associated with improved gut health, amongst physically fit participants. We also identified increased abundances of key butyrate-producing taxa (Clostridiales, Roseburia, Lachnospiraceae, and Erysipelotrichaceae) amongst these individuals, which likely contributed to the observed increases in butyrate levels. Conclusions Results from this study show that cardiorespiratory fitness is correlated with increased microbial diversity in healthy humans and that the associated changes are anchored around a set of functional cores rather than specific taxa. The microbial profiles of fit individuals favor the production of butyrate. As increased microbiota diversity and butyrate production is associated with overall host health, our findings warrant the use of exercise prescription as an adjuvant therapy in combating dysbiosis-associated diseases.
Spaceborne SAR and AIS Data Fusion for Dense Shipping Environments
Creators: name: RODGER, MAXIMILIAN BRYANT
Publisher: name: University of Surrey
Year: 2022

description: A wide range of research activities exploit spaceborne Synthetic Aperture Radar (SAR) and Automatic Identification System (AIS) for applications that contribute to maritime safety, security and sustainability. An important requirement of SAR and AIS data fusion is accurate data association (or correlation), which is the process of linking SAR ship detections and AIS observations considered to be of a common origin. The data association is particularly challenging in dense shipping environments, where ships detected in SAR imagery can be wrongly associated with AIS observations. This often results in an erroneous and/or inaccurate maritime picture which disrupts surveillance operations and negatively affects research activities that use AIS as a source of ground truth. Therefore, a classification-aided data association technique is proposed which uses a transfer learning method to classify ship types in SAR imagery. Specifically, a ship classification model is first trained on AIS data and then transferred to make predictions on SAR ship detections. These predictions are subsequently used in the data association which uses a rank-ordered assignment technique to provide a robust match between the data.
description: A series of Monte Carlo tests are performed to evaluate the performance and robustness of the classification-aided data association technique. Subsequently, two case studies of dense shipping environments in the UK are used to validate a multisensor fusion framework based on the types of SAR product used for maritime surveillance: wide-area and large-scale data association in the English Channel and focused data association in the Solent. Results show a high level of correspondence between the data that is robust to dense shipping or high traffic areas, and the confidence in the data association is improved when using class (i.e. ship type) information. Additionally, the effectiveness of co-located SAR and AIS datasets collected from the UK’s first spaceborne radar mission, NovaSAR-1, is evaluated. Finally, future research directions involving the fusion of SAR and AIS data are discussed.
Evidence for and against genetic predispositions to acute and chronic altitude illnesses
Creators: name: MacInnis, Martin J.
name: Koehle, Michael
Publisher: name: The University of British Columbia
Year: 2017

description: Humans exhibit marked variation in their responses to hypoxia, with susceptibility to acute and chronic altitude illnesses being a prominent and medically important example. Many have hypothesized that genetic differences are the cause of these variable responses to hypoxia; however, until recently, these hypotheses were based primarily on small (and sometimes anecdotal) reports pertaining to apparent differences in altitude illness susceptibility between populations, the notion that previous history of altitude illness is indicative of subsequent risk, the heritability of hypoxia-related traits, and candidate gene association studies. In the past 5 years, the use of genomic techniques has helped bolster the claim that susceptibility to some altitude illnesses is likely the result of genetic variation. For each of the major altitude illnesses, we summarize and evaluate the evidence stemming from three important characteristics of a genetic trait: (i) individual susceptibility and repeatability across assessments, (ii) biogeographical differences and familial aggregation, and (iii) association(s) with genetic variants. Evidence to support a genetic basis for susceptibilities to acute mountain sickness (AMS) and high-altitude cerebral edema (HACE) is limited, owing partially to the subjective and unclear phenotype of AMS and the rarity and severity of HACE. In contrast, recent genomic studies have identified genes that influence susceptibility to high-altitude pulmonary edema (HAPE), chronic mountain sickness (CMS), and high-altitude pulmonary hypertension (HAPH). The collection of more individual, familial, and biogeographical susceptibility data should improve our understanding of the extent to which genetic variation contributes to altitude illness susceptibility, and genomic and molecular investigations have the potential to elucidate the mechanisms that underpin altitude illness susceptibility.
Energieeffizientes Wohnen, aber wie? Die Rolle von Mittelklassen für mehr Nachhaltigkeit in Ho Chi Minh City vor dem Hintergrund des Klimawandels
Creators: name: Waibel, Michael
name: Schwede, Dirk
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Wirtschaftlicher Boom hat die Sozialstrukturen in Vietnams Metropolen verändert: Erstmals bilden sich breite Mittelschichten. Diese übernehmen zunehmend ressourcenintensive Lebensstile und werden damit zu einer Schlüsselgruppe für mehr Nachhaltigkeit. Dabei können Maßnahmen im Bereich energieeffizientes Wohnen eine zentrale Rolle spielen. (Bedauerlicherweise sind bei der Druckausgabe der südostasien 2/2009 in den Artikel von M. Waibel und D. Schwede Fehler hineingeraten, die nicht von den Autoren verschuldet sind. Die Redaktion bittet, dies zu entschuldigen. In der Online-Ausgabe ist eine korrigierte Version eingestellt.)
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 2 (2009): Ohne Moos nichts los? – Entwicklungszusammenarbeit und Armutsbekämpfung kritisch betrachtet
Tod einer tragisch Getriebenen: Die Ära der Corazon C. Aquino (1933–2009) markierte trotz größter Hoffnungen nur die Rückkehr zur Elitendemokratie
Creators: name: Werning, Rainer
Publisher: name: südostasien – Zeitschrift für Politik • Kultur • Dialog
Year: 2018

description: Maria Corazon Sumulong Cojuangco, geboren am 25. Januar 1933, entstammte einer der reichsten Familien des Landes. Die Cojuangcos beziehungsweise Teile des Cojuangco-Clans genossen in der jüngeren Geschichte des durch Klientelismus geprägten Inselstaates das Privileg, stets im Sog der Herrschenden politische Patronage zu erfahren und wirtschaftliche Pfründe einzufahren. Die nun am 1. August 2009 an Darmkrebs verstorbene Corazon Cojuangco bildete da keine Ausnahme.
description: südostasien – Zeitschrift für Politik • Kultur • Dialog, Bd. 25 Nr. 4 (2009): So nah und doch so fern: Südostasien und der arabische Raum