cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Colonisation, violence and ethics: Resisting settler colonial erasure on Dja Dja Wurrung Country
Creators: name: JESSICA KATE HODGENS
Publisher: name: Monash University
Year: 2017
Subjects: History

description: This thesis explores how violence and ethics have played out in the colonisation of Dja Dja Wurrung Country, in central Victoria. Through the interplay between oral history and archival research, it traces the history of Dja Dja Wurrung people since colonisation until the present day, and addresses some of the ethical challenges raised by this colonisation. The thesis demonstrates how settler colonisation has operated through a doubled violence of erasure that functions as a kind of ‘death work’, and is also concerned with the various forms of ‘life work’ carried out by Dja Dja Wurrung which struggle against this erasure.
Additional file 2 of Characterization of immune checkpoints expression and lymphocyte densities of iranian breast cancer patients; the co-expression status and clinicopathological associates
Creators: name: Pournabee, Mohammadhossein
name: Keshavarz-Fathi, Mahsa
name: Esmaeili, Pooyesh
name: Mahdavi Sharif, Pouya
name: Nili, Fatemeh
name: Jahanbin, Behnaz
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Table 2: Associations between the HR and HER expression states and the expression of TC PD-L1, IC PD-L1, and LAG-3
Involutions and stable subalgebras
Creators: name: Becher, Karim Johannes
name: Grenier-Boley, Nicolas
name: Tignol, Jean-Pierre
Publisher: name: arXiv
Year: 2016
Subjects: subject: K-Theory and Homology (math.KT)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: 16H05, 16R50, 16W10

description: Given a central simple algebra with involution over an arbitrary field, étale subalgebras contained in the space of symmetric elements are investigated. The method emphasizes the similarities between the various types of involutions and privileges a unified treatment for all characteristics whenever possible. As a consequence a conceptual proof of a theorem of Rowen is obtained, which asserts that every division algebra of exponent two and degree eight contains a maximal subfield that is a triquadratic extension of the centre.
Recent advances in metal complexes for antimicrobial photodynamic therapy.
Creators: name: Rees, Thomas W
name: Ho, Po-Yu
name: Hess, Jeannine
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: Chemical Biology & High Throughput
Biochemistry & Proteomics
Infectious Disease
Structural Biology & Biophysics

description: Antimicrobial resistance (AMR) is a growing global problem with more than 1 million deaths due to AMR infection in 2019 alone. New and innovative therapeutics are required to overcome this challenge. Antimicrobial photodynamic therapy (aPDT) is a rapidly growing area of research poised to provide much needed help in the fight against AMR. aPDT works by administering a photosensitizer (PS), which is activated only when irradiated with light, allowing high spatiotemporal control and selectivity. The PS typically generates reactive oxygen species (ROS), which can damage a variety of key biological targets, potentially circumventing existing resistance mechanisms. Metal complexes are well known to display excellent optoelectronic properties and recent focus has begun to shift towards their application in tackling microbial infections. We herein review the last 5 years of progress in the emerging field of small molecule metal complex PSs for aPDT.
Higgs Radiation Off Top Quarks at the Tevatron and the LHC
Creators: name: Beenakker, W.
name: Dittmaier, S.
name: Krämer, M.
name: Plümper, B.
name: Spira, M.
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
Design of an Ultra-Efficient Reversible Full Adder-Subtractor in Quantum-dot Cellular Automata
Creators: name: Taherkhani, Elham
name: Moaiyeri, Mohammad Hossein
name: Angizi, Shaahin
Publisher: name: arXiv
Year: 2016
Subjects: subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: By the progressive scaling of the feature size and power consumption in VLSI chips the part of energy dissipated due to information loss in irreversible computations will become a serious limitation in the near future. Quantum-dot cellular automata (QCA) is an emerging nanotechnology with extremely low energy dissipation which facilitates new computation paradigms such as reversible computing. In this paper a novel reversible full adder-subtractor circuit based on QCA is proposed. Our proposed design is implemented using only one layer and does not require any rotated cells which significantly improves the manufacturability of the design. In addition, it improves the cell count, area and total energy dissipation by almost 45% and 50% and 48%, respectively, as compared to the existing QCA-based single-layer and multilayer reversible full adders.
description: Optik-International Journal for Light and Electron Optics (2017)
(200805) Thomas Hadaway
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Strangers in a Strange Land: Envisioning the darker side of motherhood
Creators: name: Xeros-Constantinides, Sophia Strugnell
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Maternity is often idealized within society, where motherhood ‘myths’ paint unachievable pictures of maternal perfection and blissful union with baby. This thesis and studio-based artwork look behind the mask of maternal perfection, at what real women have said and shown of their actual experiences of maternity. The research examines the darker side of motherhood, and how this has been depicted. Through picture-making, I find new visual forms for maternity, based on the metaphor of journeying to connect with baby, and on the use of collage to give visual form to the disruption of the status quo for the woman-mother.
Genetics and genomics of key agronomic traits in field pea (Pisum sativum L.)
Creators: name: Sudheesh, Shimna
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy by published work to the School of Applied Systems Biology, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.

Thesis with publications.

Field pea (Pisum sativum L.) is a self-pollinating, diploid, cool-season food legume. Crop production is constrained by multiple abiotic (including soil salinity and boron [B] toxicity) and biotic (powdery mildew and bacterial blight infection) stress factors, that cause reduced growth and yield. Development of varieties which are tolerant to these stresses is essential, and application of molecular genetic markers could greatly accelerate this process. Advances in genomic technology have permitted the development of 768 single nucleotide polymorphism (SNP) markers associated with expressed sequence tags (ESTs). Comprehensive genetic linkage maps were generated based on existing simple sequence repeat (SSR) markers and new SNP markers for four RIL-based mapping populations of field pea. By combining these four bi-parental maps with previously published consensus maps, a comprehensive integrated structure was obtained. Comparative genomic analysis of field pea with other legume species revealed high levels of conserved synteny between the genomes. Trait dissection of resistance to bacterial blight caused by Pseudomonas syringae pv. syringae and salinity tolerance identified multiple contributory genomic regions leading to quantitative inheritance. In contrast, B toxicity tolerance, powdery mildew resistance and bacterial blight (caused by P. syringae pv. pisi) resistance were predominantly controlled by a single genomic region. Resequencing of the PsMLO1 candidate gene from powdery mildew resistant and susceptible genotypes allowed the design and validation of a putative diagnostic marker. This study also generated a comprehensive transcriptome data sets from two genotypes of field pea through the use of RNA sequencing technology (RNA-Seq), and performed comparison to gene complements in related species, sequence annotation and assessment of tissue-specific expression. The resources generated in this study will support further development of genetic markers, map construction and enhancement, identification of marker-trait associations, genomics-assisted breeding, map-based gene cloning, comparative genetics as well to identify target genes for genetic modification approaches on the basis of annotation and expression analysis.
Brane involutions on irreducible holomorphic symplectic manifolds
Creators: name: Franco, Emilio
name: Jardim, Marcos
name: Menet, Grégoire
Publisher: name: arXiv
Year: 2016
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14J28, 14J33, 14J50

description: In the context of irreducible holomorphic symplectic manifolds, we say that (anti)holomorphic (anti)symplectic involutions are brane involutions since their fixed point locus is a brane in the physicists' language, i.e. a submanifold which is either complex or lagrangian submanifold with respect to each of the three Kähler structures of the associated hyperkähler structure. Starting from a brane involution on a K3 or abelian surface, one can construct a natural brane involution on its moduli space of sheaves. We study these natural involutions and their relation with the Fourier--Mukai transform. Later, we recall the lattice-theoretical approach to Mirror Symmetry. We provide two ways of obtaining a brane involution on the mirror and we study the behaviour of the brane involutions under both mirror transformations, giving examples in the case of a K3 surface and $K3^{[2]}$-type manifolds.
description: to appear in Kyoto J. Math
title: Phenylketonuria
title: Genomic interaction and the phenotype
titleType: AlternativeTitle
Creators: name: Matalon, Reuben
name: Michals-Matalon, Kimberlee
name: Surendran, Sankar
name: Tyring, Stephen K.
Publisher: name: Technische Universität Dortmund
Year: 2004
Subjects: subject: metabolome
subject: Pah^enu2 mouse
subject: phenylalanine hydroxylase
subject: phenylketonuria
subject: proteome
subject: 610

description: Genome research is emerging as a new and important tool in biology used to obtain information on gene sequences, genomic interaction, and how genes work in concert to produce the final syndrome or phenotype. Defect in phenylalanine hydroxylase (PAH) gene result in Phenylketonuria (PKU). Molecular studies using the brain of the mouse model for PKU (PAHenu2) showed altered expression of several genes including upregulation of orexin A and a low activity of branched chain aminotransferase. These studies suggest that a single gene (PAH) defect is associated with altered expression, transcription and translation of other genes. It is the combination of the primary gene defect, the altered expression of other genes, and the new metabolic environment that is created, which lead to the phenotype.
description: EXCLI Journal ; Vol. 3, 2004
MEMORY AND METAMEMORY IN PATIENTS WITH TEMPORAL LOBE EPILEPSY
Creators: name: HOWARD, CHARLOTTE EMMA
Publisher: name: University of Plymouth
Year: 2009
Subjects: temporal lobe epilepsy,
metacognitive,
Judgement-of-Learning,
Feeling-of-Knowing

description: It is well established that patients with temporal lobe epilepsy (TLE) commonly report memory difficulties. The aim of this thesis was to use a novel approach adopting Nelson & Narens' (1990) theoretical framework to investigate whether metacognitive knowledge and memory performance were differentially disrupted in patients with TLE. More specifically, investigating to what extent poor memory in TLE could result from inadequate metamemory monitoring, inadequate metamemory control or both. Experiment I employed a combined Judgement-of-Learning and Feeling-of-Knowing task to investigate whether participants could monitor their memory successfully at both the item-by-item and global levels. The results revealed a dissociation between memory and metamemory in TLE patients. TLE patients presented with a clear episodic memory deficit compared with controls yet preserved metamemory abilities. Experiments 2 and 3 explored the sensitivity approach to examine metacognitive processes that operate during encoding in TLE patients and controls. Both these experiments demonstrated that TLE patients were sensitive to monitoring and control processes at encoding. The final experiment further investigated memory performance by examining the role of lateralisation of the seizure focus using material specific information and the 'Remember-Know' paradigm. The findings from the verbal task provided partial support to the material-specific hypothesis. The results from these experiments are discussed in terms of their association with executive functioning and memory deficits in TLE, and have important implications for future research examining memory and metamemory in TLE patients and other clinical populations.
Visualising Britain’s Holy Land
Creators: name: Burritt, Amanda Maree
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis explores nineteenth-century British Christian perceptions of the Holy Land through visual culture. The Holy Land was simultaneously viewed as a region of physical and spiritual geography, quintessentially ‘other’, yet historical home of Christianity, the inheritance of Britain and place of eschatological promise, a place of ethnographic interest and of commercial and political importance. My research analyses visual and textual sources by British artists David Roberts, Sir David Wilkie and William Holman Hunt. I demonstrate their engagement with contemporaneous questions around Christology, the significance of the Holy Land for Britain and the Protestant emphasis on the primacy of reason and experience. Further, this thesis shows that the work of Roberts, Wilkie and Hunt provoked critical and popular response. As a rhetorical medium, their artworks reflected significant theological shifts in nineteenth-century Protestant Britain. More than just mirroring these changes, however, my research shows that their work was also an impetus for further shifts in religious and visual culture and perceptions of sacred geography. Questions around the veracity of biblical narratives were dominant in religious thinking in the nineteenth century. Both the scientific discipline of Near Eastern archaeology and the development of textual criticism, as discussed in this thesis, contributed to the discourse around hermeneutics. Through their artworks Roberts, Wilkie and Hunt sought to enable British Christians to have a vicarious experience of the places in which Jesus and the prophets lived. My exploration demonstrates that, for Roberts, Wilkie and Hunt, as for other Bible focussed Protestants in nineteenth-century Britain, personal experience was a fundamental element of faith and their visualisation of the Bible was inextricably linked to the Holy Land. Through close analysis of primary source material this thesis shows that a nuanced interpretation of the motivation, religious perspectives, attitudes, behaviour and visual and textual expression of Roberts, Wilkie and Hunt is necessary to understand their differing engagements with the Holy Land and their personal identities as men of faith and as British citizens of Empire. For Roberts physical place was paramount, for Wilkie a sense of historical context was crucial and for Hunt typological symbolism was necessary to express a complex Christology. This thesis contributes to the broader discussion of nineteenth-century British visual culture through an explicit analysis of these different, but related, perspectives on engagement with the Holy Land.
A model for approximately stretched-exponential relaxation with continuously varying stretching exponents
Creators: name: Paulsen, Joseph D.
name: Nagel, Sidney R.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Relaxation in glasses is often approximated by a stretched-exponential form: $f(t) = A \exp [-(t/τ)^β]$. Here, we show that the relaxation in a model of sheared non-Brownian suspensions developed by Corté et al. [Nature Phys. 4, 420 (2008)] can be well approximated by a stretched exponential with an exponent $β$ that depends on the strain amplitude: $0.25 < β< 1$. In a one-dimensional version of the model, we show how the relaxation originates from density fluctuations in the initial particle configurations. Our analysis is in good agreement with numerical simulations and reveals a functional form for the relaxation that is distinct from, but well approximated by, a stretched-exponential function.
description: 13 pages, 9 figures
(200797) Ann Colliver
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Theory of linear sweep voltammetry with diffuse charge: unsupported electrolytes, thin films, and leaky membranes
Creators: name: Yan, David
name: Bazant, Martin Z.
name: Biesheuvel, P. M.
name: Pugh, Mary C.
name: Dawson, Francis P.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Linear sweep and cyclic voltammetry techniques are important tools for electrochemists and have a variety of applications in engineering. Voltammetry has classically been treated with the Randles-Sevcik equation, which assumes an electroneutral supported electrolyte. In this paper, we provide a comprehensive mathematical theory of voltammetry in electrochemical cells with unsupported electrolytes and for other situations where diffuse charge effects play a role, and present analytical and simulated solutions of the time-dependent Poisson-Nernst-Planck (PNP) equations with generalized Frumkin-Butler-Volmer (FBV) boundary conditions for a 1:1 electrolyte and a simple reaction. Using these solutions, we construct theoretical and simulated currentvoltage curves for liquid and solid thin films, membranes with fixed background charge, and cells with blocking electrodes. The full range of dimensionless parameters is considered, including the dimensionless Debye screening length (scaled to the electrode separation), Damkohler number (ratio of characteristic diffusion and reaction times) and dimensionless sweep rate (scaled to the thermal voltage per diffusion time). The analysis focuses on the coupling of Faradaic reactions and diffuse charge dynamics, although capacitive charging of the electrical double layers (EDL) is also studied, for early time transients at reactive electrodes and for non-reactive blocking electrodes. Our work highlights cases where diffuse charge effects are important in the context of voltammetry, and illustrates which regimes can be approximated using simple analytical expressions and which require more careful consideration.
First Symmetry Tests in Polarized Z0 Decays to b overline(b)g
Creators: name: Abe, Kenji
name: Abe, Koya
name: Abe, T.
name: Adam, I.
name: Akimoto, H.
name: Aston, D.
name: Baird, K. G.
name: Baltay, C.
name: Band, H. R.
name: Barklow, T. L.
name: Bauer, J. M.
name: Bellodi, G.
name: Berger, R.
name: Blaylock, G.
name: Bogart, J. R.
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
Ulrich Renz et al.: Die wilden Schwäne 野天鹅 // Mein allerschönster Traum 我最美的梦乡 (Deutsch-Chinesisch) (2 bilinguale Kinderbücher)
Creators: name: Berg, Christine
Publisher: name: CHUN - Chinesischunterricht
Year: 2022

description: CHUN - Chinesischunterricht, Bd. 34 (2019): CHUN - Chinesischunterricht
Improved strategies for sampling and mixture separation of trace biological materials
Creators: name: Verdon, Timothy James
Publisher: name: La Trobe
Year: 2023

description: Thesis with publications.

Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy by published work to the Department of Genetics, Institute for Molecular Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.

Effective collection of biological samples is paramount in forensic investigations as DNA profiles have become powerful tools in exculpating and inculpating individuals. Collecting mixed samples containing more than one profile decreases the probative value of evidence. There is a paucity of data informing selection of the best collection methods, especially for trace quantities of biological material. This thesis evaluated the efficacy of a range of commonly used collection devices and methods and assessed novel methods of collection and mixture separation prior to extraction. Swab types were compared for the collection of different biological fluids, plus touch DNA, from a variety of substrates. Tests were also performed to compare yields from frozen and air-dried swabs. Findings led to recommendations for the selection of swab types for specific sample/substrate combinations. The efficacy of two tapes for collection of biological evidence from various fabrics was compared, both to each other and to swabbing. Significant differences were found between the two tape types, and swabbing was more effective than taping in some instances. The data characterised a threshold, related to tape adhesion, beyond which taping will no longer be effective. Gluelifting with the Pinpoint DNA Isolation System was evaluated as a method for sampling DNA from non-porous surfaces. Its yield was comparable to, and less variable than, swabbing from rough surfaces. A novel strategy was designed and tested to differentially tapelift DNA from separate, layered deposits on either the same or reverse side of fabric. Although the study did not yield separated profiles, it highlighted the extent of migration of biological material through some porous substrates. Preliminary assessment of flow cytometric cell separation for mixtures of human biological fluids using cell-specific antibodies was conducted. This effectively recovered dropped-out profiles from mixed samples. Cumulatively, these findings provide significant opportunities for forensic practitioners to enhance the recovery and probative value of trace samples and thus better service the justice system.
Reconstruction of an effective magnon mean free path distribution from spin Seebeck measurements in thin films
Creators: name: Chavez-Angel, E.
name: Zarate, R. A.
name: Fuentes, S.
name: Guo, E. J.
name: Klaui, M.
name: Jakob, G.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A thorough understanding of the mean-free-path (MFP) distribution of the energy carriers is crucial to engineer and tune the transport properties of materials. In this context, a significant body of work has investigated the phonon and electron MFP distribution, however, similar studies of the magnon MFP distribution have not been carried out so far. In this work, we used thickness-dependence measurements of the longitudinal spin Seebeck (LSSE) effect of yttrium iron garnet films to reconstruct the cumulative distribution of a SSE related effective magnon MFP. By using the experimental data reported by Guo et al. [Phys. Rev. X 6, 031012 (2016)], we adapted the phonon MFP reconstruction algorithm proposed by A.J. Minnich, [Phys. Rev. Lett. 109, 205901 (2012)] and apply it to magnons. The reconstruction showed that magnons with different MFP contribute in different manner to the total LSSE and the effective magnon MFP distribution spreads far beyond their typical averaged values.
description: 16 pages, 5 figures
Additional file 1 of In silico secretome analyses of the polyphagous root-knot nematode Meloidogyne javanica: a resource for studying M. javanica secreted proteins
Creators: name: Macharia, Teresia Nyambura
name: Duong, Tuan A.
name: Moleleki, Lucy Novungayo
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Supplementary Material 1
Efficiency Improvement and Analysis of Changes in Microstructure Associated to a Uniform Pressure Actuator
Creators: name: Arroyo, A.
name: Daehn, G. S.
name: Eguia, I.
name: Fernandez, J. I.
name: Garuz, I.
name: Jimbert, P.
name: Silveira, E.
Publisher: name: Institut für Umformtechnik - Technische Universität Dortmund
Year: 2006
Subjects: subject: high velocity forming
subject: pressure distribution
subject: uniform pressure coil
subject: 620
subject: 670

description: During the 1st international Conference on HIGH SPEED FORMING held in Dortmund in 2004 a new forming coil giving significant advantages was presented in the framework of ongoing R&D programs at OSU (The Ohio State University). It established the improvement provided by the return path for currents induced in the workpiece. To quantify the mentioned improvement, Labein has performed classical cone forming experiments with both configurations and analyzed energetic efficiency using well known alloys, more precisely AA 6016 and 1050. Both deformation mechanisms and contour analysis of the specimens were studied. General purpose multi-turn coils provide pressure distributions not extended to the whole forming area, resulting in zones undergoing significant delay as die the deformation sequence is referred. As a result, varied deformation patterns can be found along the contour of a cone specimen formed in such way. Firstly, a macroscopic survey of the specimens shows that uniform pressure distributes deformation over the entire formed area during the deformation process. Secondly, the effect on efficiency provided by this new coil concept is focuses not only on the ability for distributing deformation, but on the energy required to create such deformation. Finally, to validate the whole simulation, the predicted strain level, shape, and internal energy of the workpiece are compared with the experimental specimens. A key point in the validation process is checking the internal energy. It is known that the ratio of stored energy to deformation energy ranges in the order of 30 %. The procedure for the experiments follows this methodology.
(200799) James Robertson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Minimization of errors in narrowband laser phase noise measurements based on reference measurement channels
Creators: name: Pnev, A. B.
name: Stepanov, K. V.
name: Dvoretskiy, D. A.
name: Zhirnov, A. A.
name: Nesterov, E. T.
name: Sazonkin, S. G.
name: Chernutsky, A. O.
name: Shelestov, D. A.
name: Fedorov, A. K.
name: Svelto, C.
name: Karasik, V. E.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We propose a novel scheme for laser phase noise measurements with minimized sensitivity to external fluctuations including interferometer vibration, temperature instability, other low-frequency noise, and relative intensity noise. In order to minimize the effect of these external fluctuations, we employ simultaneous measurement of two spectrally separated channels in the scheme. We present an algorithm for selection of the desired signal to extract the phase noise. Experimental results demonstrate potential of the suggested scheme for a wide range of technological applications.
description: 4 pages, 4 figures; published version
The deaths of Thomas Lawrence & The bereaved writer: composing a language of sensations
Creators: name: Hanson, Peter Geoffrey
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Through a novel, "The Deaths of Thomas Lawrence", and an exegesis, "The Bereaved Writer: Composing a Language of Sensations", this study explores the condition of bereavement from a materialist perspective, examines how grievers experience the world, and considers how they can render that experience in language. Rather than view bereavement as a purely emotional state induced by a significant loss, this study conceives of bereavement as a condition defined primarily by a physical disruption to a body’s sense of self: identity, sovereignty and conception of “meaningfulness”. This project contends that without a distinct subjective position from which to have personal experiences, and without stable conceptual schemas through which to interpret the world, the bereaved body connects more directly to the raw and impersonal materiality of its surroundings and has nonhuman intensities grafted onto it from those surroundings. Put differently, this project views what it terms the bereaved-body as what French poststructuralist theorists Gilles Deleuze (1925-95) and Félix Guattari (1930-92) call a ‘haecceity’: an amalgam of nonsubjectified intensities that consists ‘entirely of relations of movement and rest between molecules or particles, capacities to affect and be affected’ (A Thousand Plateaus 261). Rather than a bereaved-body using language to present the experiences and judgements of a subjective and rational perspective, this project proposes that a bereaved-body can instead utilise an unorthodox writing style to intensively compose its desubjectified condition and to compose the transformative forces in its surroundings. A bereaved-body that produces such an intensive composition is what this study refers to as a bereaved-writer. This study also uses Deleuze and Guattari’s conception of the artist and their concept of ‘a language of sensations’ to inform these notions of a bereaved-writer and an intensive composition: Deleuze and Guattari view the artist as a ‘becomer’ who ‘goes beyond the perceptual states and affective transitions of the lived’ (What is Philosophy? 171); and the French theorists describe a language of sensations as a text in which the writer ‘twists language, makes it vibrate, seizes hold of it, and rends it in order to wrest the percept from perceptions, the affect from affections, the sensation from opinion’ (What is Philosophy? 176). Thomas Lawrence, a young man writing in a state of bereavement after the loss of his father in Victoria’s 2009 Black Saturday bushfires, is an example of a bereaved-writer or a “becomer”, and The Deaths of Thomas Lawrence, as the novel he narrates, is an example of an intensive composition or a language of sensations.
Structural studies of poxvirus mediated inhibition of host cell apoptosis
Creators: name: Burton, Denis R.
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Biochemistry, School of Molecular Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.

In multi-cellular organisms, apoptosis plays an important role in homeostasis. However, apoptosis also plays a major role as a powerful immune response. Because of its profound impact on cellular integrity, multiple mechanisms evolved to ensure appropriate triggering or inhibition. Viral invasion of a host cell is one event capable of triggering apoptosis. DNA viruses posses a large genome, encoding molecular responses against many pathways inducing apoptosis. One of them is the expression of viral Bcl-2 homologs that interfere with the Bcl-2 mediated signaling designed to activate Bak and Bax, two proteins essential to permeabillize the outer mitochondrial membrane. Cellular Bcl-2 proteins harbour four characteristic Bcl-2 Homology (BH) domains. A noteworthy feature of their viral counterparts is the typically low level of sequence identity between viral and cellular Bcl-2 proteins. Most poxviral vBcl-2 proteins do not harbor readily identifiable BH domains. Despite this observation, these viral proteins efficiently prevent intrinsic mediated apoptosis. Previous studies identified two potential poxviral Bcl-2 proteins: DPV022 and SPPV14. Strong evidence suggests that they could display the same activity of the previously identified M11L and F1L. However, whether or not DPV022 and SPPV14 adopt a Bcl-2 fold remains unclear. I determined the oligomeric state of each protein and assessed the binding affinity of DPV022 to BH3-peptides. Using the identified ligand binding profile, I determined three structures of complexes between DPV022 with Bim, Bak and Bax. These structures revealed features suggesting a common ancestor that was shared with cellular Bcl-2 proteins. Based on my findings I postulate the existence of at least two classes of poxviral Bcl-2 proteins: monomeric proteins, which bind numerous ligands with high affinity, and dimeric vBcl-2 proteins with less ligands and lower affinities Although several attempts were made, determination of a crystal structure of SPPV14 was unsuccessful. In its absence a homology model was generated on the basis of the determined crystal structure of DPV022 and the structure of M11L. The final model revealed essential binding interactions shared with DPV022 and cellular Bcl-2. In its totality the work presented in this thesis enabled a better understanding of the poxviral Bcl-2 proteins, the potential molecular origin and their molecular mechanism of action.
Ursolic acid-based 24-nor- and A-seco-24-oxy-triterpenoids
Creators: name: Zakirova, Liana
name: Baikova, Irina
name: Lobov, Alexander
name: Каzakova, Oxana
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: Using methyl 2-cyano-3,4-seco-12(13),4(23)-diene-ursolate as a starting scaffold a series of 3-oxo-24-nor-ursolate and A-seco-ursanes holding hydroxy-, furoyloxy-, p-tosyloxy- as well as aldehyde fragments at C24 that possess cytotoxic activity has been synthesised. The structures of the new ursanes were confirmed by detailed spectral data analysis. The chemoselectivity of methyl 2-cyano-3,4-seco-12(13),4(23)-diene-ursolate oxidation involving the double bond in the A cycle was observed.
Volterra-type Ornstein-Uhlenbeck processes in space and time
Creators: name: Pham, Viet Son
name: Chong, Carsten
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60G10, 60G17, 60G60, 60H20, 60G48, 60G51, 60J75

description: We propose a novel class of tempo-spatial Ornstein-Uhlenbeck processes as solutions to Lévy-driven Volterra equations with additive noise and multiplicative drift. After formulating conditions for the existence and uniqueness of solutions, we derive an explicit solution formula and discuss distributional properties such as stationarity, second-order structure and short versus long memory. Furthermore, we analyze in detail the path properties of the solution process. In particular, we introduce different notions of càdlàg paths in space and time and establish conditions for the existence of versions with these regularity properties. The theoretical results are accompanied by illustrative examples.
(200801) Mary Sarah Faulkner
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Loading and compression of a single two-dimensional Bose gas in an optical accordion
Creators: name: Ville, J. L.
name: Bienaimé, T.
name: Saint-Jalm, R.
name: Corman, L.
name: Aidelsburger, M.
name: Chomaz, L.
name: Kleinlein, K.
name: Perconte, D.
name: Nascimbène, S.
name: Dalibard, J.
name: Beugnon, J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The experimental realization of 2D Bose gases with a tunable interaction strength is an important challenge for the study of ultracold quantum matter. Here we report on the realization of an optical accordion creating a lattice potential with a spacing that can be dynamically tuned between 11$\,μ$m and 2$\,μ$m. We show that we can load ultracold $^{87}$Rb atoms into a single node of this optical lattice in the large spacing configuration and then decrease nearly adiabatically the spacing to reach a strong harmonic confinement with frequencies larger than $ω_z/2π=10\,$kHz. Atoms are trapped in an additional flat-bottom in-plane potential that is shaped with a high resolution. By combining these tools we create custom-shaped uniform 2D Bose gases with tunable confinement along the transverse direction and hence with a tunable interaction strength.
A Dictyostelium model for neuronal ceroid lipofuscinoses (Batten disease)
Creators: name: Chavan, Anita
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Microbiology, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora.

Batten Disease or Neuronal Ceroid Lipofuscinosis (NCL) is a neurodegenerative disease of a childhood that arises from mutations affecting one of 14 lysosomal or endoplasmic reticulum (ER) or plasma membrane proteins. Deficiencies in CLN5 and CLN7 cause the Finnish and Turkish variant forms of late infantile NCL respectively. A D. discoideum model was created successfully for studying these forms of Batten Disease by altering CLN5 and CLN7 protein levels using antisense inhibition and overexpression approaches. CLN5 deficiency caused abnormalities in cell growth, endocytosis, autophagy and lysosomal pH regulation. CLN7 has been hypothesized to function as a lysosomal transport protein and I found direct evidence for this in the form of altered lysosomal uptake of Neutral Red in our CLN7 transformants. In vitro lysosomal uptake assays showed that Neutral Red uptake could be inhibited, presumably competitively, by a variety of but not all potential substrates. The uptake was independent of ionophores that abolish proton, potassium and charge gradients, suggesting that CLN7 mediates the passive transport of its substrates. When CLN7 expression was altered in D. discoideum, defects in cell growth, endocytosis, autophagic cell death, lysosomal pH, volume and osmoregulation were observed. Cotransformation experiments to assess genetic interactions showed that the Rheb signalling pathway mediates the defects in phagocytosis observed when CLN7 expression levels are altered. However, the elevated rates of pinocytosis caused by CLN7 deficiency appear not to be mediated by inhibition of Rheb signalling. Thus my results suggest that simulating Batten Disease in D. discoideum by altering CLN5 and CLN7 protein expression affects cell signalling pathways that regulate vesicle trafficking in autophagy and endocytosis.
Additional file 1 of Characterization of immune checkpoints expression and lymphocyte densities of iranian breast cancer patients; the co-expression status and clinicopathological associates
Creators: name: Pournabee, Mohammadhossein
name: Keshavarz-Fathi, Mahsa
name: Esmaeili, Pooyesh
name: Mahdavi Sharif, Pouya
name: Nili, Fatemeh
name: Jahanbin, Behnaz
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Supplementary Table 1: Associations between gradings of breast cancer and the expression of TC PD-L1, IC PD-L1, and LAG-3
New perspective for black hole thermodynamics in Gauss-Bonnet-Born-Infeld massive gravity
Creators: name: Hendi, Seyed Hossein
name: Li, Gu-Qiang
name: Mo, Jie-Xiong
name: Panahiyan, Shahram
name: Panah, Behzad Eslam
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Following earlier study regarding Einstein-Gauss-Bonnet-massive black holes in the presence of Born-Infeld nonlinear electromagnetic field [S. H. Hendi, B. Eslam Panah and S. Panahiyan, arXiv:1510.00108], we study thermodynamical structure and critical behavior of these black holes through various methods in this paper. Geometrical thermodynamics is employed to give a picture regarding phase transition of these black holes. Next, a new method is used to derive critical pressure and horizon radius of these black holes. In addition, Maxwell equal area law is employed to study the Van der Waals like behavior of these black holes. Moreover, the critical exponents are calculated and by using Ehrenfest equations, the type of the phase transitions are determined.
description: 18 pages, 10 figures and 7 tables. Matches published version
Connecting Nature Deliverable 2: Report on the outcomes of the lessons learned, mapping of emerging experiments and expert workshops, leading to a synthesis of the most promising indicators for nature-based solutions
Creators: name: Dumitru, Adina
name: Peralbo Rubio, Eva
name: Tomé Lourido, David
name: Collier, Marcus J.
name: Dick, Gillian
name: Dymek, Dominika
name: Dziubała, Agnieszka
name: Fagiewicz, Katarzyna
name: Lupa, Piotr
name: Mikuła, Łukasz
name: Poniży, Lidia
name: Quartier, Mien
name: Sermpezi, Rania
name: Vos, Peter
name: Van de Sijpe, Katrien
name: Zwierzchowska, Iwona
Publisher: name: Zenodo
Year: 2021
Subjects: Nature-based solutions
Governance
Green infrastructure
Ecosystem services
Resilience
Connecting Nature
Genk
Poznan
Glasgow
Impact Assessment
Connecting Nature Framework

description: This Deliverable presents the Connecting Nature Impact Assessment framework and capacity-building process whose aim has been to support the mainstreaming of a culture of impact evaluation and evidence-based nature-based solutions (NBS) design and implementation in cities. The framework is the result of a co-production process between academic and city council partners in the project and has been implemented in the cities, leading to the development of monitoring and evaluation plans for specific NBS exemplars at different scales. Additional capacity-building tools have been created to integrate the impact assessment framework into regular urban planning processes, such as an impact assessment training programme, and a digitally-supported impact assessment tool guiding cities through the process of thinking about and designing their monitoring and evaluation strategy. We present the Connecting Nature Impact Assessment Framework, and we illustrate it with the monitoring and evaluation plans of the front-runner cities. We then focus on an analysis of the main challenges experienced and lessons learned in this process of capacity building, to enhance transferability; we present how knowledge has been transferred to fast-follower and multiplier cities, and we finalize by drawing conclusions on the most promising indicators for NBS in cities, focusing on those indicators that have already been tested in practice.
description: Suggested citation: Dumitru, A., Peralbo Rubio, E., Tomé Lourido, D., Collier, M.J., Dick, G., Dymek, D., Dziubaba, A., Fagiewicz, K., Lupa, P., Mikuła, L., Poniży, L., Quartier, M., Sermpezi, R., Vos, P., and Zwierzchowska, I. (2021) Connecting Nature Deliverable 2: Report on the outcomes of the lessons learned, mapping of emerging experiments and expert workshops, leading to a synthesis of the most promising indicators for nature-based solutions. DOI: https:/doi.org/10.5281/zenodo.7010920