cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A study of Pyropheophorbide-a based photosensitisers for photodynamic therapy
Creators: name: Pye, Hayley
Publisher: name: Imperial College London
Year: 2014

description: Photodynamic therapy (PDT) is an approved but under-development modality for cancer therapy. Conventional, non-targeted PDT consists of administration of a photosensitiser to the patient, passive accumulation in the tumour, localised photosensitiser activation using visible light and subsequent cellular destruction via reactive oxygen species (ROS) and/or free radicals. A major limitation of PDT is its poor selectivity for tumours and a suboptimal pharmacokinetic / biodistribution profile. This leads to low potency and patient photosensitivity. This is being addressed with the development of antibody targeted PDT; the conjugation of multiple photosensitisers to a tumour-specific antibody. For effective antibody conjugation photosensitisers are preferable if highly water soluble. PPa (Pyropheophorbide-a) is an effective photosensitiser and more soluble versions have been prepared to aid in its conjugation. The work presented in this thesis explores the differences these novel, soluble photosensitisers exhibit in terms of toxicity, cell death mechanisms and uptake in an in vitro model of traditional PDT and also in terms of improvements in their bio-conjugation. Data presented shows chemical manipulation of PPa significantly affects the biochemical properties important for effective PDT. PEG-modified PPa (PS-1, with enhanced solubility over PPa) as an un-conjugated drug exhibits similar overall toxicity to PPa, along with similar hallmarks for caspase-independent apoptosis, however this equivalent toxicity is achieved despite a significantly reduced cellular uptake. Its toxicity therefore is higher per internalised molecule than its parent compound. This is hypothesised to be due to enhanced retention of photo-physical properties in a cellular environment. Cationic PPa (PS4, with even greater enhanced solubility over PPa) exhibits a loss in cytotoxicity in comparable levels of free photosensitiser studied; this is hypothesised to be due to decreased uptake in addition to an altered cellular localisation. Derivatives of PS1 activated for conjugation showed greatly enhanced reaction with antibody compared to PPa showing its promise for improved targeted PDT, PS4 proved too difficult to chemically activate in the time frame of this project.
Sphex variegata Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Sphex
Sphex variegata

description: Sphex variegata [spec. nov.]
S. nigra tota, alis albo maculatis.
Habitat in Europa.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 570, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Oral history interview with Paul Smith 1990
Publisher: name: Columbia University
Year: 2019
Subjects: Museum directors
Decorative arts--History--20th century.--United States
Handicraft--History--20th century.--United States

description: Born 1931, childhood Bennington, NY; education: attended Art Institute of Buffalo and the School for American Craftsmen in Rochester, NY, 1987 awarded Honorary Doctorate of Fine Arts by the New School University, Parsons School of Design; career: work for the American Craftsmen's Council, Director American Craft Museum, juror in numerous international craft competitions, work with numerous foundations, work with numerous craft, art and design organizations; interview: early 1950s education and work with craft organizations, late 1950s joined the staff of the American Craftsmen's Council in NY, importance of Dave Campbell and Aileen Webb to the American craft movement and museum, assumed directorship of the American Craft Museum in 1963, process of designing exhibitions and building museum attendance, national craft work, movement of museum to new space in 1979 and 1986, changes in administration of museum through the 1980s, move to director emeritus, CRAFT TODAY: Poetry of the Physical, overview of craft art and enterprise.
DEVELOPMENT OF CREATIVE MEDIA TO INCREASE INSPIRATION AND SELF-ESTEEM FOR ORPHANS IN THE THREE SOUTHERN BORDER PROVINCES OF THAILAND
Creators: name: Chineephen MALISUWAN
Publisher: name: Asian Crime and Society Review
Year: 2023
Subjects: Creative Media
Inspiration
Self-Esteem
Orphan
Thailand’s Three Southern Border Provinces

description: Asian Crime and Society Review, 10, 2, 8-17
Extraordinary Activity in the BL Lac Object OJ~287
Creators: name: Hughes, Philip A.
name: Aller, Hugh D.
name: Aller, Margo F.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We use a continuous wavelet transform to analyze more than two decades of data for the BL~Lac object OJ~287 acquired as part of the UMRAO variability program. We find clear evidence for a persistent modulation of the total flux and polarization with period $\sim 1.66$ years, and for another signal that dominates activity in the 1980s with period $\sim 1.12$ years. The relationship between these two variations can be understood in terms of a `shock-in-jet' model, in which the longer time scale periodicity is associated with an otherwise quiescent jet, and the shorter time scale activity is associated with the passage of a shock; the different periodicities of these two components may reflect different internal conditions of the two flow domains, leading to different wave speeds, or different contractions of a single underlying periodicity, due to the different Doppler factors of the two flow components. We suggest that the modulation arises from a wave driven by some asymmetric disturbance close to the central engine. The periodic behavior in polarization exhibits excursions in $U$ which correspond to a direction $\sim 45^{\circ}$ from the VLBI jet axis. This behavior is not explained by the random walk in the $Q$-$U$ plane which is expected from models in which a pattern of randomly aligned magnetic field elements propagate across the visible portion of the flow, and suggests a small amplitude, cyclic variation in the flow direction in that part of the flow that dominates cm-wavelength emission.
description: Text: 22 pages, PostScript line figures: 10 pages, GIF color figures: 7. High quality PostScript versions of the GIF images may be obtained from the "Wavelets/First Results" section of http://www.astro.lsa.umich.edu/users/hughes/, or by anon. ftp from file get/hughes/waves.tar.gz at ra.astro.lsa.umich.edu. Submitted to Ap. J
COMMITMENT AND JOB SATISFACTION AS MECHANISMS CONNECTING ETHICAL LEADERSHIP AND CSR WITH TURNOVER INTENTION
Creators: name: Puthisat NAMDECH
Publisher: name: Asian Crime and Society Review
Year: 2023
Subjects: Commitment
Job Satisfaction
Ethical Leadership
Corporate Social Responsibility
Turnover Intention

description: Asian Crime and Society Review, 10, 2, 29-39
Infinities within graviton scattering amplitudes
Creators: name: Dunbar, D. C.
name: Norridge, P. S.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present unitarity as a method for determining the infinities present in graviton scattering amplitudes. The infinities are a combination of IR and UV. By understanding the soft singularities we may extract the UV infinities and relate these to counter-terms in the effective action. As an demonstration of this method we rederive the UV infinities present at one-loop when gravity is coupled to matter.
description: revised version
Insights into endotoxin-mediated lung inflammation and future treatment strategies
Creators: name: Amlan Chakraborty
name: Boer, Jennifer C.
name: Selomulya, Cordelia
name: Plebanski, Magdalena
name: Royce, Simon G.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Introduction: Airway inflammatory disorders are prevalent diseases in need of better management and new therapeutics. Immunotherapies offer a solution to the problem of corticosteroid resistance. Areas covered: The current review focuses on lipopolysaccharide (Gram-negative bacterial endotoxin)-mediated inflammation in the lung and the animal models used to study related diseases. Endotoxin-induced lung pathology is usually initiated by antigen presenting cells (APC). We will discuss different subsets of APC including lung dendritic cells and macrophages, and their role in responding to endotoxin and environmental challenges. Expert commentary: The pharmacotherapeutic considerations to combat airway inflammation should cost-effectively improve quality of life with sustainable and safe strategies. Selectively targeting APCs in the lung offer the potential for a promising new strategy for the better management and treatment of inflammatory lung disease.
Additional file 3: of Desired improvements of working conditions among medical assistants in Germany: a cross-sectional study
Creators: name: Scharf, Jessica
name: Vu-Eickmann, Patricia
name: Li, Jian
name: MĂźller, Andreas
name: Wilm, Stefan
name: Angerer, Peter
name: Loerbroks, Adrian
Publisher: name: figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Associations of sociodemographic and practice-relevant determinants with task-related independence (ordinal logistic regression) (DOC 63 kb)
Attacks against a Simplified Experimentally Feasible Semiquantum Key Distribution Protocol
Creators: name: Boyer, Michel
name: Liss, Rotem
name: Mor, Tal
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Cryptography and Security (cs.CR)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: A semiquantum key distribution (SQKD) protocol makes it possible for a quantum party and a classical party to generate a secret shared key. However, many existing SQKD protocols are not experimentally feasible in a secure way using current technology. An experimentally feasible SQKD protocol, "classical Alice with a controllable mirror" (the "Mirror protocol"), has recently been presented and proved completely robust, but it is more complicated than other SQKD protocols. Here we prove a simpler variant of the Mirror protocol (the "simplified Mirror protocol") to be completely non-robust by presenting two possible attacks against it. Our results show that the complexity of the Mirror protocol is at least partly necessary for achieving robustness.
description: 9 pages
Search via Parallel Lévy Walks on $\mathbb{Z}^2$
Creators: name: Clementi, Andrea
name: d'Amore, Francesco
name: Giakkoupis, George
name: Natale, Emanuele
Publisher: name: arXiv
Year: 2020
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Probability (math.PR)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: FOS: Biological sciences

description: Motivated by the Lévy foraging hypothesis -- the premise that various animal species have adapted to follow Lévy walks to optimize their search efficiency -- we study the parallel hitting time of Lévy walks on the infinite two-dimensional grid. We consider $k$ independent discrete-time Lévy walks, with the same exponent $α\in(1,\infty)$, that start from the same node, and analyze the number of steps until the first walk visits a given target at distance $\ell$. We show that for any choice of $k$ and $\ell$ from a large range, there is a unique optimal exponent $α_{k,\ell} \in (2,3)$, for which the hitting time is $\tilde O(\ell^2/k)$ w.h.p., while modifying the exponent by an $ε$ term increases the hitting time by a polynomial factor, or the walks fail to hit the target almost surely. Based on that, we propose a surprisingly simple and effective parallel search strategy, for the setting where $k$ and $\ell$ are unknown: the exponent of each Lévy walk is just chosen independently and uniformly at random from the interval $(2,3)$. This strategy achieves optimal search time (modulo polylogarithmic factors) among all possible algorithms (even centralized ones that know $k$). Our results should be contrasted with a line of previous work showing that the exponent $α= 2$ is optimal for various search problems. In our setting of $k$ parallel walks, we show that the optimal exponent depends on $k$ and $\ell$, and that randomizing the choice of the exponents works simultaneously for all $k$ and $\ell$.
Investigating the role of vitamin A and retinoic acid signalling in lung homeostasis and repair
Creators: name: Mongey, Roisin
Publisher: name: Imperial College London
Year: 2021

description: The human lung is capable of endogenous repair, but the underlying mechanisms which control this remain unclear. Many of the processes involved in lung repair are thought to be similar to those required during alveolar development. As such, the targeting of factors involved in lung development provides a potential therapeutic route for the induction of endogenous repair mechanisms. Retinoic acid (RA), obtained wholly from dietary vitamin A (vit A), is an essential mediator of lung development and can promote regeneration in experimental animal models of alveolar insufficiency. We aimed to investigate the role of RA in mediating lung structural homeostasis and repair using a multi-disciplinary, epidemiological and lab-based approach. We identified a positive role for dietary vit A in the modulation of adult lung function in a large UK population-based study. Using genetic data from this study, we have also identified single nucleotide polymorphisms (SNPs) in RA pathway genes that modulate lung function, some of which interact with vit A intake. At a cellular level, we used an in vitro scratch assay model to show that treatment with exogenous RA directly promotes endothelial repair but does not affect epithelial repair, either directly or via paracrine signalling from the endothelium. To study the role of RA in 3D alveolar tissue, we developed the acid injury and repair (AIR) model, a novel ex vivo tool in which the response to injury and subsequent repair mechanisms can be determined. By examining established cellular markers of repair in the AIR model, we discovered that the number of progenitor cells increases in damaged regions of tissue whereas in the uninjured areas of the same PCLS, proliferation increases without a concomitant increase in progenitor cells. Manipulation of RA signalling using pharmacological inhibitors resulted in a significant reduction in proliferation following injury. RA reporter mice, which express GFP linked to the RA response element, were used to visualise active RA signalling. By combining this reporter line with the AIR model, we found GFP expression, indicative of active RA signalling, in postnatal day 7 PCLS and observed an increase in GFP signal following injury in adult PCLS. Overall, our findings suggest that RA signalling primarily affects the capillary endothelium during lung repair and that at a population level, a vit A rich diet could be used to modify lung function. Together this multidisciplinary approach provides important insight into the mechanisms underlying the role of RA in lung repair and regeneration and suggests that regulation of vitamin A levels through nutritional intake may provide a route to help maintain adult lung function.
COMPARATIVE STUDY OF TRANSPORT FACILITATION ISSUES IN ASEAN TRANSPORT FACILITATION AGREEMENTS AND GREATER MEKONG SUBREGION CROSS BORDER TRANSPORT AGREEMENT
Creators: name: Chackrit DUANGPHASTRA
Publisher: name: Asian Crime and Society Review
Year: 2024
Subjects: Transport Facilitation
ASEAN
Greater Mekong Subregion
Cross Border Transport

description: Asian Crime and Society Review, 11, 1, 1-8
Sphex indica Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Sphex
Sphex indica

description: Sphex indica [spec. nov.]
S. atra, pedibus antennisque ferrugineis, alis atro-cae- rulescentibus. M. L. U.
Habitat in Indiis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 571, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
title: ADCO, Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Cart. 173 (11 H 939), 226 folios, f. 0308
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0308, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour la grange et seigneurie d'Ouges (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 173 (11 H 939), 226 folios, f. 0308, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Oral history interview with Paul Streeten, 2001
Publisher: name: Columbia University
Year: 2020
Subjects: Economic policy--International cooperation
International economic relations
Economic development
Economic assistance
Human rights
International business enterprises
Basic needs--Developing countries
Poverty

description: (b. 1917) Early years: involvement in socialist youth movement; interest in human development; Blue Pilgrims; student of economics at Aberdeen University and Cambridge; 1940 incarceration and interment camp in UK and Canada; Heinz Arndt in internment camp; enlistment in army; injury in Sicily; 1945 Ministry of Overseas Development; Career: lecturer and fellow at Oxford; author of The Political Element; professor emeritus at Boston University; editor of World Development; deputy director general of the Economic Planning Staff of the UK's Ministry of Overseas Development; acting director of the Institute of Development Studies at University of Sussex; Warden of Queen Elizabeth House, Oxford; 1976-1980 and 1984-1985 senior adviser at World Bank; Themes: Austro-Marxism; collaboration with Gunnar Myrdal--first executive-secretary for the Economic Commission for Europe; cumulative causation; centralization of the World Bank; decentralization of the UN; impressions of Ava and Gunnar Myrdal and Michal Kalecki; intermediate regimes; foreign exchange gap; Indian Statistical Institute at Mahalonobis; fixed income distribution; internal politics at Ministry of Overseas Development; involvement in International Development Association (IDA) and Asian Development Bank; UNCTAD reports; development in India and Malta; "labor utilization" and "livelihoods"; third-world countries and basic needs (material and nonmaterial); calculations of economic growth; interdisciplinary problem-solving at UN; dissemination of ideas by UN; resurgence of neoclassical theory in development; gap between research and implementation at World Bank; human rights approach versus basic needs approach; structuralism and the World Bank; pessimism of UN, optimism of World Bank; UN intervention during human rights violations; international investment trust for recycling; necessity of international migration agency, international environmental agency, global taxing agency, and global central bank in UN; modernization of New International Economic Order (NIEO); fair compensation in global arena; bilateralism versus multilateralism; life expectancy projections; Human Development Index; cultural diversity and human rights; human sustainable development; poverty reduction and inequality; absolute and relative poverty; widening definitions of capital; import substitution and export promotion; free trade and protectionism; importance of teaching economic history; writing style and clarity of UN documents
SL(2, Z) Duality and 4-Dimensional Noncommutative Theories
Creators: name: Lu, J. X.
name: Roy, S.
name: Singh, H.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate how the four-dimensional noncommutative open string/Yang-Mills theory behaves under a general non-perturbative quantum $SL(2,Z)$ symmetry transformation. We discuss this by considering D3 branes in a constant background of axion, dilaton, and electric and magnetic fields (including both $ {\bf E} \perp {\bf B}$ and {\bf E}$||${\bf B} cases) in the respective decoupling limit. We find that the value of axion, whether rational or irrational, determines the nature of the resulting theory under $SL(2,Z)$ as well as its properties such as the coupling constant and the number of noncommutative directions. In particular, a strongly coupled theory with an irrational value of axion can never be physically equivalent to a weakly coupled theory while this is usually true for a theory with a rational value of axion. A noncommutative Yang-Mills (NCYM) (resulting from D3 branes with pure magnetic flux) is physically equivalent to a noncommutative open string (NCOS) but if the value of axion is irrational, we also have noncommutative space-space directions in addition to the usual noncommutative space-time directions for NCOS. We also find in general that a NCOS cannot be physically equivalent to a NCYM but to another NCOS if the value of axion is irrational. We find another new decoupling limit for possible light-like NCYM whose $SL(2,Z)$ duality is a light-like ordinary Yang-Mills if the value of the axion is rational. Various related questions are also discussed.
description: 22 pages, latex
Frequently recurrent operators
Creators: name: Bonilla, Antonio
name: Grosse-Erdmann, Karl-G.
name: López-Martínez, Antoni
name: Peris, Alfred
Publisher: name: arXiv
Year: 2020
Subjects: subject: Functional Analysis (math.FA)
subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 47A16 (Primary) 47B37 (Secondary)

description: Motivated by a recent investigation of Costakis et al. on the notion of recurrence in linear dynamics, we study various stronger forms of recurrence for linear operators, in particular that of frequent recurrence. We study, among other things, the relationship between a type of recurrence and the corresponding notion of hypercyclicity, the influence of power boundedness, and the interplay between recurrence and spectral properties. We obtain, in particular, Ansari- and Léon-Müller-type theorems for $\mathcal{F}$-recurrence under very weak assumptions on the Furstenberg family $\mathcal{F}$. This allows us, as a by-product, to deduce Ansari- and Léon-Müller-type theorems for $\mathcal{F}$-hypercyclicity.
Psychophysical and Psychological Factors Affecting Recovery from Acute Balance Disorders
Creators: name: Cousins, Sian Emma
Publisher: name: Imperial College London
Year: 2012

description: Patients with acute vestibular neuritis are traditionally investigated with caloric or rotational examination of the vestibular-ocular reflex. However, clinical outcome is poorly predicted by such vestibular reflex assessments. We hypothesised that symptomatic recovery would depend upon higher order visuo-vestibular compensatory mechanisms. Thirty-one patients were studied in the acute and recovery phases of vestibular neuritis (median 2 days and 10 weeks, respectively). Patients underwent examination of vestibulo-ocular and vestibular-perceptual responses, at threshold and supra-threshold levels. Supra-threshold stimuli (90°/s velocity step rotations) allowed quantification of vestibulo-ocular and vestibulo-perceptual time constants. Additional measures of visual dependency (rod-and-disc task), dizziness symptom load (Vertigo Symptom Scale and Dizziness Handicap Inventory) and psychological factors (including - autonomic arousal, anxiety, depression, fear of bodily sensations) were obtained. Vestibulo-perceptual and vestibulo-ocular thresholds were raised and asymmetric acutely and remained slightly elevated and asymmetric at recovery. Acutely, supra-threshold vestibulo-ocular time constants were shortened and asymmetric. In contrast, perceptual responses were reduced but notably symmetrical. At recovery, vestibulo-ocular supra-threshold responses remained abnormal but perceptual supra-threshold responses normalised. Visual dependency was significantly elevated above normals in both acute and recovery stages. Vertigo symptom recovery was significantly predicted by acute levels of visual dependency (p=0.002), autonomic anxiety (p=0.004). A number of measures were associated with vertigo symptoms at recovery, in addition to visual dependency (p=0.012) and autonomic anxiety (p<0.001), including - anxiety and depression (p<0.003), fear of body sensations (p=0.033), vestibular perceptual thresholds (p=0.017) and caloric canal paresis (p=0.001). Factor Analysis revealed a strong association between clinical outcome, visual dependency and psychological factors, all loading on a single component accounting for 59.15% of the variance. The bilateral suppression of supra-threshold vestibular perception observed acutely represents a hitherto unrecognised central adaptive ‘anti-vertiginous’ mechanism. However, poor symptomatic recovery is best predicted by increased visual dependency and psychological factors. The findings show that long term recovery from unilateral vestibular deficit is mediated by central compensatory mechanisms, including multi-sensory integration and psychological processing.
THE INDONESIAN TERRORISM RISK ASSESSMENTS TO OFFENDERS: A CASE STUDY BEFORE AND DURING A PANDEMIC
Creators: name: SUKABDI, Zora A.
Publisher: name: Asian Crime and Society Review
Year: 2024
Subjects: Terrorism
Pandemic
Criminogenic Risks
Psychological Profiles
Assessment
Risk-Need-Responsivity

description: Asian Crime and Society Review, 11, 1, 9-29
Exact renormalization group study of fermionic theories
Creators: name: Comellas, Jordi
name: Kubyshin, Yuri
name: Moreno, Enrique
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The exact renormalization group approach (ERG) is developed for the case of pure fermionic theories by deriving a Grassmann version of the ERG equation and applying it to the study of fixed point solutions and critical exponents of the two-dimensional chiral Gross-Neveu model. An approximation based on the derivative expansion and a further truncation in the number of fields is used. Two solutions are obtained analytically in the limit $N\to \infty $, with N being the number of fermionic species. For finite N some fixed point solutions, with their anomalous dimensions and critical exponents, are computed numerically. The issue of separation of physical results from the numerous spurious ones is discussed. We argue that one of the solutions we find can be identified with that of Dashen and Frishman, whereas the others seem to be new ones.
description: 28 pages, 4 PostScipt figures, plain TeX. Final version to appear in Nucl. Phys. B
Extensions of Veech groups I: A hyperbolic action
Creators: name: Dowdall, Spencer
name: Durham, Matthew G.
name: Leininger, Christopher J.
name: Sisto, Alessandro
Publisher: name: arXiv
Year: 2020
Subjects: subject: Geometric Topology (math.GT)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20F67, 20F65, 30F60, 57M60, 57M07

description: Given a lattice Veech group in the mapping class group of a closed surface $S$, this paper investigates the geometry of $Γ$, the associated $π_1S$--extension group. We prove that $Γ$ is the fundamental group of a bundle with a singular Euclidean-by-hyperbolic geometry. Our main result is that collapsing "obvious" product regions of the universal cover produces an action of $Γ$ on a hyperbolic space, retaining most of the geometry of $Γ$. This action is a key ingredient in the sequel where we show that $Γ$ is hierarchically hyperbolic and quasi-isometrically rigid.
description: v3: 45 pages; minor revisions incorporating referee comments; final version accepted for publication in the Journal of Topology; v4: corrected citation for Lemma 4.10
Additional file 1: of cVEMP correlated with imbalance in a mouse model of vestibular disorder
Creators: name: Negishi-Oshino, Reina
name: Ohgami, Nobutaka
name: He, Tingchao
name: Ohgami, Kyoko
name: Li, Xiang
name: Kato, Masashi
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Developmental Biology

description: Figure S1. Typical waveforms of cVEMP with head tilt and the background. Figure S2. Vestibular hair cell loss in the saccule and utricle of mice treated with IDPN. Figure S3. Amplitude of preceding negative wave and amplitude of p1-n1.Figure S4. Typical ABR waveforms of the control group (A) and the IDPN group (B) at 20–80 dB SPL of 4 kHz sound are presented at the same scales. Figure S5. cVEMP recording in normal mice under anesthesia or under wakefulness. Figure S6. Typical waveforms of cVEMP elicited by sound stimulation of 500 Hz and 1000 Hz. Figure S7. Unilateral cVEMP recording and immunohistostaining of hair cells in the otoconia and cupula from each ear of gentamicin-treated mice. Figure S8. Correlations between scores of the behavior tests. (PDF 1630 kb)
Improved Rainfall Downscaling for Real-Time Urban Pluvial Flood Forecasting
Creators: name: Wang, Li-Pen
Publisher: name: Imperial College London
Year: 2012

description: Traditionally, hydrologists had a relatively minor role in rainfall data processing; they usually simply took data from meteorologists. However, meteorological organisations usually provide weather service over a larger area and scale (i.e. country level); the applicability of this large-scale information to urban hydrological applications is therefore questionable. This work tries to provide a local view on rainfall processing, aiming to improve the suitability (in terms of accuracy and resolution) of operational rainfall data for urban hydrological uses. This work explores advanced downscaling and adjustment techniques to address the identified issues in urban hydrology: accuracy and resolution. On the basis of a a review and the testing of state of the art techniques, the Bayesian-based adjustment technique and the newly-developed cascade-based downscaling techniques are found to be suitable tools to improve respectively the accuracy, and the resolution of operational radar (and raingauge) rainfall estimates. In addition, a combined application of these two techniques is tested; the results suggested that, although extra uncertainty may appear, this combination demonstrates a clear potential for providing accurate and high-resolution (street-scale and 5-min) rainfall estimates.
Modelling of local elastic buckling for steel beams with web openings
Creators: name: Zainal Abidin, Ahmad Razin
Publisher: name: Imperial College London
Year: 2013

description: This work is mainly concerned with the development of sophisticated yet efficient methods for assessing the elastic buckling of steel beams with web openings, focussing on local buckling effects in the web region. A new computational method is proposed which extends the use of the Element Free Galerkin (EFG) method for the numerical discretisation combined with a simplified buckling assessment approach based on the Rotational Spring Analogy (RSA). The new approach considers several potential simplifications offering a balance between computational efficiency and accuracy in local buckling analysis. In the present EFG/RSA method, considerable advantage is established by separating the planar and out-of-plane responses. Planar analysis is further enhanced using modular concepts, where the beam is divided into unit cells, each of which resembles a super-element with a reduced number of freedoms, and solved using a standard discrete procedure. As for the out-of-plane analysis, the application of a ‘local region’ is adopted to significantly reduce the size of the original buckling problem. Finally, local buckling assessment is conducted using an effective approach that utilises an iterative procedure based on a rank 2 reduced eigenvalue problem along with a shifting local region. Several illustrative examples are provided which highlight the efficiency and accuracy of the developed approach in comparison with detailed nonlinear finite element analysis performed using ADAPTIC, and which demonstrate general applicability to local buckling analysis of steel beams with web openings of various shapes and sizes. This work also considers the development of a simplified design-oriented method which is presented particularly for web-post buckling. Towards this end, a simplified analytical model is proposed based on an analogy with equivalent rectangular thin beams (RTB), where a semi-empirical approach is used to calibrate the suggested formulation against the results obtained from the numerical work performed earlier.
ECONOMIC AND SOCIAL DEVELOPMENT TO REDUCE INEQUALITY AMONG SMALL-BOAT FISHING GROUPS WITH LOW-INCOME
Creators: name: Laor MAMAH
Publisher: name: Asian Crime and Society Review
Year: 2024
Subjects: Inequality
Small Boat Fishing Groups
Processing High-Value Seafood Products
Saving Money

description: Asian Crime and Society Review, 11, 1, 30-39
Palatini formulation of $f(R,T)$ gravity theory, and its cosmological implications
Creators: name: Wu, Jimin
name: Li, Guangjie
name: Harko, Tiberiu
name: Liang, Shi-Dong
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the Palatini formulation of $f(R,T)$ gravity theory, in which a nonminimal coupling between the Ricci scalar and the trace of the energy-momentum tensor is introduced, by considering the metric and the affine connection as independent field variables. The field equations and the equations of motion for massive test particles are derived, and we show that the independent connection can be expressed as the Levi-Civita connection of an auxiliary, energy-momentum trace dependent metric, related to the physical metric by a conformal transformation. Similarly to the metric case, the field equations impose the non-conservation of the energy-momentum tensor. We obtain the explicit form of the equations of motion for massive test particles in the case of a perfect fluid, and the expression of the extra-force, which is identical to the one obtained in the metric case. The thermodynamic interpretation of the theory is also briefly discussed. We investigate in detail the cosmological implications of the theory, and we obtain the generalized Friedmann equations of the $f(R,T)$ gravity in the Palatini formulation. Cosmological models with Lagrangians of the type $f=R-α^2/R+g(T)$ and $f=R+α^2R^2+g(T)$ are investigated. These models lead to evolution equations whose solutions describe accelerating Universes at late times.
description: 22 pages, no figures, accepted for publication in EPJC; references added
Sphex tropica Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Sphex
Sphex tropica

description: Sphex tropica [spec. nov.]
S. nigra, oculis albis, abdominis segmento secundo latiore ferrugineo. M. L. U.
Habitat in Indiis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 571, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
D6.6 Policy Recommendations for the Integration of CNH within RIS3/4
Creators: name: Matei, Alexandru
Publisher: name: Zenodo
Year: 2022

description: The following policy document aimsto: 1) fill the knowledge and implementation gap regarding the underexplored potential of Cultural and Natural Heritage (CNH), and 2) make the case for its inclusion as a priority component in Research and Innovation Strategies for Smart Specialisation (RIS3). The recommendations are based on specific insights derived from: The 35th Breakfast at Sustainability’s dialogue (Nov. 2020), RURITAGE Deliverable 7.5 “Thinking beyond the COVID-19 crisis: heritage-based opportunities for rural regeneration” (Oct. 2020), The JRC/COR Joint workshop on smart specialisation for recovery (Apr. 2021), and The RURITAGE Board of Regions Workshop (Nov. 2021)
A New Equilibrium for Accretion Disks Around Black Holes
Creators: name: Krolik, J. H.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Accretion disks around black holes in which the shear stress is proportional to the total pressure, the accretion rate is more than a small fraction of Eddington, and the matter is distributed smoothly are both thermally and viscously unstable in their inner portions. The nonlinear endstate of these instabilities is uncertain. Here a new inhomogeneous equilibrium is proposed which is both thermally and viscously stable. In this equilibrium the majority of the mass is in dense clumps, while a minority reaches temperatures $\sim 10^9$ K. The requirements of dynamical and thermal equilibrium completely determine the parameters of this system, and these are found to be in good agreement with the parameters derived from observations of accreting black holes, both in active galactic nuclei and in stellar binary systems.
description: AAS LaTeX, accepted to Ap. J. Letters
Playing With Friends -- The Importance of Social Play During the COVID-19 Pandemic
Creators: name: Cmentowski, Sebastian
name: Krüger, Jens
Publisher: name: arXiv
Year: 2020
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: In early 2020, the virus SARS-CoV-2 evolved into a new pandemic, forcing governments worldwide to establish social distancing measures. Consequently, people had to switch to online media, such as social networks or videotelephony, to keep in touch with friends and family. In this context, online games, combining entertainment with social interactions, also experienced a notable growth. In our work, we focused on the potential of games as a replacement for social contacts in the COVID-19 crisis. Our online survey results indicate that the value of games for social needs depends on individual gaming habits. Participants playing mostly multiplayer games increased their playtime and mentioned social play as a key motivator. Contrarily, non-players were not motivated to add games as communication channels. We deduce that such crises mainly catalyze existing gaming habits.
title: Электроника и схемотехника
title: Учебное пособие для СПО
titleType: Subtitle
Creators: name: Шошин Е.Л.
Publisher: name: Профобразование, Ай Пи Ар Медиа
Year: 2020

description: В учебном пособии рассмотрены теоретические основы электроники и схемотехники, в частности вопросы работы полупроводниковых приборов. Изложены физические явления, протекающие в диодах, транзисторах, силовых и оптоэлектронных приборах, операционных усилителях. Описана система схемотехнического моделирования Micro-Cap. Подготовлено с учетом требований Федерального государственного образовательного стандарта среднего профессионального образования. Предназначено для студентов технических специальностей и профессий, изучающих дисциплины «Основы электроники и схемотехники», «Электротехника и электроника», «Электроника».
Least-square based recursive optimization for distance-based source localization
Creators: name: Nguyen, Thien-Minh
name: Xie, Lihua
Publisher: name: arXiv
Year: 2018
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In this paper we study the problem of driving an agent to an unknown source whose location is estimated in real-time by a recursive optimization algorithm. The optimization criterion is subject to a least-square cost function constructed from the distance measurements to the target combined with the agent's self-odometry. In this work, two important issues concerning real world application are directly addressed, which is a discrete-time recursive algorithm for concurrent control and estimation, and consideration for input saturation. It is proven that with proper choices of the system's parameters, stability of all system states, including on-board estimator variables and the agent-target relative position can be achieved. The convergence of the agent's position to the target is also investigated via numerical simulation.
Electrically Charged Topological Solitons
Creators: name: Gomes, J. F.
name: Gueuvoghlanian, E. P.
name: Sotkov, G. M.
name: Zimerman, A. H.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Two new families of T-Dual integrable models of dyonic type are constructed. They represent specific $A_n^{(1)}$ singular Non-Abelian Affine Toda models having U(1) global symmetry. Their 1-soliton spectrum contains both neutral and U(1) charged topological solitons sharing the main properties of 4-dimensional Yang-Mills-Higgs monopoles and dyons. The semiclassical quantization of these solutions as well as the exact counterterms and the coupling constant renormalization are studied.
description: 40 pages, latex, typos corrected in eq. (2.3), new section on spin of solitons added, extended discussion on T-duality relation between axial and vector topological theta terms in new subsection 2.5
Fermion masses, mass-mixing and the almost commutative geometry of the Standard Model
Creators: name: Dabrowski, Ludwik
name: Sitarz, Andrzej
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Quantum Algebra (math.QA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We investigate whether the Standard Model, within the accuracy of current experimental measurements, satisfies the Hodge duality condition introduced and studied in Dabrowski, D'Andrea, Sitarz, Lett Math Phys (2018) 108:1323. We show that the neutrino and quark mass-mixing and the difference of fermion masses is necessary for this property. We demonstrate that the current data supports the new geometric feature of the Standard Model, Hodge duality, provided that all neutrinos are massive.
description: 19 pages
Sphex gibba Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Sphex
Sphex gibba

description: Sphex gibba [spec. nov.]
S. nigra, abdomine ferrugineo apice fusco, alis primoribus apice nigricantibus.
Habitat in Svecia.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 571, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
The Role of FOXO3a in the Cellular Stress Response and Metabolism of Breast Cancer Cells
Creators: name: Wilson, Miranda Sophie Claire
Publisher: name: Imperial College London
Year: 2012

description: The development of acquired resistance to chemotherapeutic drugs is often a limiting factor in the treatment of cancer. In this study, I investigated alterations in MAP kinase signalling and metabolism in a doxorubicin/epirubicin-resistant breast cancer cell line. Doxorubicin, also known as adriamycin, is one of the most important drugs in the treatment of breast cancer. The MAP kinases ERK, JNK, and p38 have all been linked to drug response and tumorigenesis, as well as apoptosis, in different cell types. I found that ERK activity was downregulated in the resistant cell line, while transcripts of the ERK phosphatases DUSP5 and DUSP6 were enriched. The resistant cells also contain less FOXO3a, a broadly pro-apoptotic transcription factor that regulates many aspects of cellular activity. I also used NMR-based metabonomics to generate a metabolic profile of the parental and doxorubicin-resistant cell lines. Many metabolic changes are seen during tumorigenesis, with further changes seen after the development of drug resistance. An increase in glycolysis is the best known, but alterations in choline metabolism and glutamine usage are also commonly seen in cancer. My results confirmed an increase in glycolysis in the resistant cells, as well as altered glutamine metabolism, and also provided novel findings for future work. The reduction in intracellular glutamine in the resistant cells was correlated with a loss of expression of the metabolic enzyme glutamine synthetase. My results show that the doxorubicin-sensitive parental cell line expresses glutamine synthetase, which was required for maximal proliferation rate. Conversely, the lack of glutamine synthetase in the doxorubicin-resistant cells caused them to be dependent on the provision of extracellular glutamine for growth. This may have implications for the treatment of drug resistant breast cancers.