cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Cadernos de Saúde, v. 3 n. Especial (2010): Infecção associada à prática de cuidados de saúde
title: Infecção associada à prática de cuidados de saúde
titleType: AlternativeTitle
Creators: name: Cadernos De Saúde
Publisher: name: Cadernos de Saúde
Year: 2010

description: Editorial...7-7 Programa do Congresso Infecção Associada à Prática dos Cuidados de Saúde...9-11 Health-care associated pneumonia (HCAP): aetiology and antimicrobial resistances...13-16 Infecção em cuidados de saúde: perspectiva actual...17-23 Epidemiologia da infecção hospitalar...25-31 Introdução à mesa-redonda sobre prevenção e controlo das infecções associadas à prestação de cuidados de saúde...33-33 Infecção do aparelho urinário...35-38 Introdução à mesa-redonda sobre o ambiente, condicionantes sociais e infecção...39-39 O ambiente na transmissão da infecção...41-45 Alterações climáticas e patologia infecciosa...47-52 Infecções em cuidados continuados: saúde mental...53-58 Transmissão da infecção em infantários e jardins de infância...59-60 Introdução à mesa-redonda sobre infecção em cuidados de saúde...61-62 Tuberculose: epidemiologia e estratégias de prevenção...63-67 Feridas crónicas: fisiopatologia e tratamento...69-75 Metodologia das comissões de controlo da infecção...77-83 Introdução à mesa-redonda sobre resistência aos antibacterianos e infecção associada aos cuidados de saúde...85-86 Resistência em bactérias de gram-positivo...87-92 Resistência em bactérias de gram-negativo...93-99 Profilaxia antibiótica...101-106 Bacteriófagos no tratamento de feridas...107-108 Controlo de surto por pseudomonas aeruginosa num serviço de neonatologia...109-111 Tiragem molecular de pseudomonas aeruginosa pelo Sistema DiversiLab...113-116 Agentes etiológicos em infecções do tracto urinário e sua susceptibilidade aos antimicrobianos...117-120
Cadernos de Pedagogia Social, n. 4 (2012)
Creators: name: Cadernos De Pedagogia Social
Publisher: name: Cadernos de Pedagogia Social
Year: 2012

description: Pedagogia social: um campo plural de investigação e intervenção...5-8 Pedagogia social nas escolas: um olhar sobre a mediação e educação social...9-26 Pedagogia social e matemática: um encontro inevitável...27-41 Reconhecimento de aprendizagens prévias: breve ensaio sobre novas oportunidades de cumprir a aprendizagem ao longo da vida...43-73 A investigação-ação como estratégia privilegiada no contexto da inserção sociolaboral de reclusos: uma leitura a partir da pedagogia social...75-90 Acolher em família: uma resposta para as crianças em perigo. Um projeto de investigação sobre o acolhimento familiar no Porto...91-103 Gente de lugar nenhum – reflexão sobre a animação sociocultural em contexto institucional para terceira idade...105-117 No mundo de hoje: atitudes perante as pessoas idosas...119-152 Diferentes experiências, uma nova convivência...153-163 Nós entre nós...165-184 A relação socioeducativa como prática de relação de dádiva...185-196 Contributos para a pedagogia social: neuroética. Educação vagarosa e ubuntu...197-219
Additional file 1 of Nitric oxide-releasing micelles with intelligent targeting for enhanced anti-tumor effect of cisplatin in hypoxia
Creators: name: Chen, Yan
name: Fang, Lei
name: Zhou, Weixin
name: Chang, Jinghan
name: Zhang, Xiaojuan
name: He, Chuanchuan
name: Chen, Chen
name: Yan, Ruicong
name: Yan, Yakai
name: Lu, Yao
name: Xu, Chuanrui
name: Xiang, Guangya
Publisher: name: figshare
Year: 2021
Subjects: Biophysics
Biochemistry
Space Science
Cell Biology
Pharmacology
Cancer

description: Additional file 1: Table S1. Composition of different micelles. Scheme S1. Synthesis scheme of TPGS-3NO3. Scheme S2. Synthesis scheme of PBA-PEG2000-DSPE. Fig. S1. 1H NMR of 3NO3-OH in DMSO-d6. Fig. S2. 13C NMR of 3NO3-OH in DMSO-d6. Fig. S3. 1H NMR of TPGS-3NO3 in chloroform-d. Characteristic peaks as marked in the graphs. Fig. S4. HRMS of TPGS-3NO3. Fig. S5. 1H NMR of PBA-PEG2000-DSPE in chloroform-d. Characteristic peaks as marked in the graphs. Fig. S6. HRMS of PBA-PEG2000-DSPE. Fig. S7. Dynamic light scattering (DLS) size measurement of CTP/CDDP. Fig. S8. Stability of CTP/CDDP at 4 ℃ for 4 weeks as measured by the particle size and zeta potential during storage. Data are expressed as mean ± SD (n = 3). Fig. S9. Leakage rate of a NO and b CDDP from CTP/CDDP during storage at 4 ℃. Data are expressed as mean ± SD (n = 3). Fig. S10. The combination stability assay of PBA-COS conjugate at different time points. Fig. S11. Cellular uptake of MCF-7 cells after incubation with different drug formulations at pH 6.5 or 7.4 for 3 h. Fig. S12. Cellular uptake of L02 cells after incubation with different drug formulations at pH 7.4 for 3 h. Fig. S13. CLSM images of 4T1 cells after incubation with CTP/CDDP/C6 for 1 h or 3 h. Fig. S14. Intracellular NO level in 4T1 cells after administration of CTP/CDDP for 0, 12 and 24 h. Fig. S15. In vitro anti-tumor effects of different drug formulations. IC50 was calculated to evaluate the cytotoxicity of various drug formulations after incubation with MCF-7 cells for 24 h under a normoxia and b hypoxia. Data are expressed as mean ± SD (n = 3), *p < 0.05, **p < 0.01. Fig. S16. The quantification of cell apoptosis. Data are expressed as mean ± SD (n = 3), ***p < 0.001. Fig. S17. CDDP biodistribution in tissues of 4T1 xenograft tumor-bearing mice at 12 h after intravenous injection. Data are expressed as mean ± SD (n = 5). Fig. S18. In vivo anti-tumor efficiency of different drug formulations in mice bearing 4T1 xenograft tumors. Tumor apoptosis was determined by TUNEL assay. Fig. S19. Values of biochemical indexes of liver and kidney containing (a) BUN, b CRE, c ALT and d AST. Data are expressed as mean ± SD (n = 5), *p < 0.05, **p < 0.01. Fig. S20. In vivo anti-metastasis effect. Image of excised lung tissues at the end of the experiment (day 21 after tumor inoculation). Data are expressed as mean ± SD (n = 5).
Identifying Latent Structures in Restricted Latent Class Models
Creators: name: Gongjun Xu
name: Zhuoran Shang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: This paper focuses on a family of restricted latent structure models with wide applications in psychological and educational assessment, where the model parameters are restricted via a latent structure matrix to reflect pre-specified assumptions on the latent attributes. Such a latent matrix is often provided by experts and assumed to be correct upon construction, yet it may be subjective and misspecified. Recognizing this problem, researchers have been developing methods to estimate the matrix from data. However, the fundamental issue of the identifiability of the latent structure matrix has not been addressed until now. The first goal of this paper is to establish identifiability conditions that ensure the estimability of the structure matrix. With the theoretical development, the second part of the paper proposes a likelihood-based method to estimate the latent structure from the data. Simulation studies show that the proposed method outperforms the existing approaches. We further illustrate the method through a data set in educational assessment.
Synthesis, characterization, and antifungal activity of novel chromene oxadiazole based dithiocarbamates
Creators: name: Konda, Santosh Kumar
name: Gutam, Madhu
name: Thalari, Gangadhar
name: Bhoga, Srinivas
name: Nayaki, Salva Reddy
name: Mattela, Kutumbarao
name: Krupadanam, G. L. David
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology
subject: 60506 Virology

description: A series of novel conjugated chromene oxadiazole-based dithiocarbamate (5a–i) derivatives have been synthesized from oxadiazole (4a–c) intermediates with carbon disulfide. The structures of all the newly synthesized compounds were established by IR, NMR, and Mass spectral analysis. The synthesized derivatives were screened for their antifungal activity against Aspergillus niger fungal strain and the results showed that some of the derivatives were found to exhibit good antifungal activity.
Exposure to Benzene in a Pooled Analysis of Petroleum Industry Case-Control Studies
Creators: name: D C Glass
name: A R Schnatter
name: G Tang
name: T W Armstrong
name: L Rushton
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Cases of lymphohematopoietic cancer from three petroleum industry cohorts, matched to controls from the respective cohort, were pooled into single study. Average benzene exposure was quantitatively estimated in ppm for each job based on measured data from the relevant country, adjusted for the specific time period, site and job exposure characteristics and the certainty of the exposure estimate scored. The probability of dermal exposure and of peak exposure was also assessed. Before risk was examined, an exposure estimate comparison and rationalisation exercise was performed across the studies to ensure accuracy and consistency of approach. This paper evaluates the final exposure estimates and their use in the risk assessments. Overall benzene exposure estimates were low, 90% of participants accumulated less than 20ppm-years. Mean cumulative exposure was estimated as 5.15ppm-years, mean duration was 22years, and mean exposure intensity was 0.2ppm. 46% of participants were allocated a peak exposure (>3ppm at least weekly). 40% of participants had a high probability of dermal exposure (based on the relative probability of at least weekly exposure). There were differences in mean intensity of exposure, probability of peak and/or dermal exposure associated with job category, job site and decade of exposure. Terminal Operators handling benzene-containing products were the most highly exposed group, followed by Tanker Drivers carrying gasoline. Exposures were higher around 1940–1950 and lower in more recent decades. Overall confidence in the exposure estimates was highest for recently-held jobs and for White Collar jobs. We used sensitivity analyses which included and excluded case-sets on the basis of exposure certainty scores, to inform the risk assessment. The above analyses demonstrated that the different patterns of exposure across the three studies are largely attributable to differences in jobs, site types and time frames rather than study. This provides reassurance that the previous rationalisation of exposures achieved inter-study consistency and that the data could be confidently pooled.
Highly atom efficient synthesis of 2,2,4,5-tetrasubstituted 3(2H)-furanones having both hydroxyl and amino substituents
Creators: name: Antony, Jesna
name: Musthafa, Sumi P.
name: Natarajan, Rakesh
name: Mathai, Sindhu
name: Devaky, Karakkattu S.
name: Rappai, John P.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: We have developed a highly atom efficient synthesis of tetrasubstituted 3(2H)-furanones from easily accessible starting materials such as C,N-diarylaldonitrones and dibenzoylacetylene. Control experiments revealed that reaction of aldonitrones having electron-withdrawing groups on the C-aryl substituent in polar aprotic solvents exhibited high product selectivity while reaction temperature has only a negligible effect on product yield and selectivity.
The Role of Inferences in Constructing, Communicating, & Sustaining Behaviour Change Arguments
Creators: name: Wells, Simon
name: Baker-Graham, Alex
name: Pangbourne, Kate
Publisher: name: figshare
Year: 2017
Subjects: subject: 80709 Social and Community Informatics
subject: FOS: Media and communications

description: Our ECA 2017 Poster
Cadernos de Saúde, v. 3 n. 2 (2010)
Creators: name: Cadernos De Saúde
Publisher: name: Cadernos de Saúde
Year: 2010

description: Editorial...5-5 Canas de pesca e canivetes suíços para a aprendizagem: duas décadas de experiência no ensino de fisiologia a alunos de Medicina...7-12 Validação da escala de Zarit: sobrecarga do cuidador em cuidados paliativos domiciliários, para população portuguesa...13-19 Equipas de cuidados paliativos domiciliários: quantas e onde são necessárias em Portugal...21-26 Aprendizagem baseada em problemas no desenvolvimento profissional contínuo médico: uma experiência...27-52 Docentes de enfermagem em Portugal: a realidade dos professores em regime de dedicação exclusiva...53-64
Mapping Increasingly Large Networks of Argumentative Inferences
Creators: name: Wells, Simon
name: Khartabil, Dana
Publisher: name: figshare
Year: 2017
Subjects: subject: 120307 Visual Communication Design (incl. Graphic Design)
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Our poster from ECA 2017
Cadernos de Pedagogia Social, n. 3 (2009)
Creators: name: Cadernos De Pedagogia Social
Publisher: name: Cadernos de Pedagogia Social
Year: 2009

description: Apresentação...5-7 A educação de todos e ao longo de toda a vida e a regulação sociocomunitária da educação...9-34 Aprender na e com a vida – a problematização da experiência como processo de consciencialização...35-44 Mediação comunitária e mudança social...45-59 As responsabilidades sociais da Escola e dos profissionais da educação que aí intervêm: contributo para um debate...61-73 A deficiência como expressão de diversidade – contributos da pedagogia social...75-90 Rendimento Social de Inserção – uma política social de desenvolvimento humano?...91-108 Ética do voluntariado...109-132 A dádiva, o tempo e o trabalho voluntário...133-139 Critical Commentary: Social Work Ethics...141-157 Changes of Foster Care System in Lithuania...157-171
Heck reaction in the synthesis of D-π-A chromophores: The effect of donor and acceptor on the ratio of 1,2- trans- and 1,1-isomer olefins
Creators: name: Islamova, Liliya N.
name: Fazleeva, Guzel M.
name: Sharipova, Sirina M.
name: Shustikov, Alexey A.
name: Tanysheva, Ekaterina G.
name: Kalinin, Alexey A.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Science Policy
subject: 60506 Virology

description: The effect of substituents in the aniline donor and the type of heterocyclic acceptor/donor moieties on the yields of 1,2-trans- and 1,1-isomer ethylene D-π-A chromophores in Pd-catalyzed Heck reaction has been studied. Various D-π-A chromophores – derivatives of quinoline, quinoxaline, benzothiazole, carbazole and indolizine – were synthesized.
Additional file 1 of Moderate ethanol exposure disrupts energy homesotasis between central and peripheral system in APP/PS1 mice
Creators: name: Kang, Shinwoo
name: Lee, Jeyeon
name: Min, Paul H.
name: Choi, Doo-Sup
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Mental Health
subject: Computational Biology

description: Supplementary Material 1
A facile synthesis of quinoxalines by using SO42−/ZrO2-TiO2 as an efficient and recyclable heterogeneous catalyst
Creators: name: Shelke, Sushil V.
name: Dhumal, Sambhaji T.
name: Karale, Akshay Y.
name: Deshmukh, Tejshri R.
name: Patil, Meghshyam K.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Quinoxaline derivatives have been synthesized in good to excellent yields by the cyclocondensation reaction of o-pheneylenediamine with substituted phenacyl bromides/benzil in the presence of SO42−/ZrO2-TiO2 as an efficient and heterogeneous catalyst. The catalyst can be recovered up to five catalytic cycles without significant loss in catalytic activity. The reported SO42−/ZrO2-TiO2 catalyst has been thoroughly characterized by using infrared spectroscopy, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and powder X-ray diffraction (XRD). Here, we have used ethanol as a green solvent in this cyclocondensation. This new method has several advantages, such as excellent yields, short reaction time, nontoxic, and easily recoverable catalyst.
First fossil evidence of Hylodesmum palaeoglutinosum from India and comments on its extinction from the subcontinent
Creators: name: Hazra, Taposhi
name: Hazra, Manoshi
name: Spicer, Robert A.
name: Spicer, Teresa E. V.
name: Bera, Subir
name: Khan, Mahasin Ali
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: We report for the first-time well-preserved leaflets of Hylodesmum palaeoglutinosum from the latest Neogene sediments (Rajdanda Formation: Pliocene) of Jharkhand, eastern India. Macromorphological features show that the fossil leaflet remains are identical to those of modern endemic taxon H. glutinosum (Muhl. ex Wild.) Ohashi & Mill (tribe: Desmodieae, subfamily: Papilionoideae; family: Fabaceae). This is the first authentic record of the occurrence of leaflets comparable to H. glutinosum from the Cenozoic sediments of India, and even worldwide. At present H. glutinosum does not grow in India, nor Southeast Asia, but is restricted to North America. Analysis of these fossil remains with respect to the modern distribution pattern of H. glutinosum and the physiognomic characters (including acuminate “drip tips”) of the fossil leaflets suggests that a tropical evergreen forest was growing under a warm, humid climate at the time of deposition. This interpretation agrees with earlier published qualitative climate interpretations for the area, and our recently published quantitative climatic data obtained from the study of leaf remains recovered from the same formation. Here, we discuss the possible causes of disappearance of this fabaceous taxon from the present-day vegetation of Chotanagpur Plateau area, eastern India and also comment on its extinction in India. The disappearance may be related to the gradual intensification of rainfall seasonality since the Pliocene.
Cadernos de Saúde, v. 3 n. 1 (2010)
Creators: name: Cadernos De Saúde
Publisher: name: Cadernos de Saúde
Year: 2010

description: Editorial...5-5 O desafio das Neurociências...7-17 Os “genes da linguagem” e a linguagem dos genes...19-31 Modelo de ensino aprendizagem em grupos numa disciplina clínica do curso de Medicina...33-56 Os processos fonológicos na fala da criança de cinco anos: tipologia e frequência...57-72 Adaptação e validação da Resilience Scale® de Wagnild e Young para a cultura portuguesa...73-80
title: Cadernos de Pedagogia Social, n. 2 (2008): Educação e solidariedade social
title: Educação e solidariedade social
titleType: AlternativeTitle
Creators: name: Cadernos De Pedagogia Social
Publisher: name: Cadernos de Pedagogia Social
Year: 2008

description: Nota de apresentação...5-6 Pedagogia Social: uma ciência, um saber profissional, uma filosofia de acção...7-30 Estatuto antropológico e limiares epistemológicos da educação social...31-43 Educadores sociais: Quem são? O que fazem? Como desejam ser reconhecidos?...45-60 O perfil profissional do educador especializado (social) - uma leitura sócio-histórica...61-80 A educação intergeracional no horizonte da educação social: compromisso do nosso tempo...81-100 Espaço, universo de relações e a questão da alteridade. Uma reflexão sobre a cidade de São Paulo/Brasil...101-115 Porque necessitamos de um modelo bioecológico–transaccional para pensar o futuro?...117-123 Intervenção social da Ald No Gúruè...125-149 Direito ao trabalho e cidadania social – a educação ao serviço da solidariedadel...151-162 Situações de risco: jovens “sem projecto de vida”, a construção de um objecto de estudo...163-178 Resiliência num grupo de adolescentes de risco de uma escola secundária do grande Porto...179-199
Ecosystem services provided by Prosopis cineraria (L.) Druce in the drylands of Southern and Western Asia
Creators: name: Baibout, Myriam
name: Corcket, Emmanuel
name: Kothari, Shanker L.
name: Fievet, Virgil
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Plant Biology

description: Trees of the Mimosoideae are dominant species in hot subdesert areas worldwide, providing many services for ecosystems and humans. This group includes Prosopis cineraria (L.) Druce, a dominant species from the dryland forests of Southern and Western Asia. Human population density and activities in these arid areas have led to calls for an urgent consideration of ecosystem services and conservation biodiversity. We performed a literature review on P. cineraria, to determine how this species could contribute to ecosystem conservation, ecosystem restoration, and improving ecosystem services in its native distribution range. Prosopis cineraria is at the heart of a network of intricate interactions with biotic and abiotic factors in its environment. Water mobilization, nitrogen fixation, soil stabilization, and the shade and resources provided by P. cineraria are key elements in the consideration of this species for conservation programs. Moreover, P. cineraria is deeply entrenched in local culture and history. It is part of the local cultural identity and provides remedies, agro-ecological, recreational, and regulating services, such as protecting dunes against erosion. Prosopis cineraria is of huge ethnobotanical value in subdesert areas in its native range. Dryland forest conservation strategies could benefit greatly from targeting this species, and should be accompanied by research in the potential of P. cineraria for coping with climate change.
Introduction to Differential Geometry of Space Curves and Surfaces
Creators: name: Sochi, Taha
Publisher: name: figshare
Year: 2017
Subjects: Geometry

description: The book, which consists of 260 pages, is about differential geometry of space curves and surfaces. The formulation and presentation are largely based on a tensor calculus approach. It can be used as part of a course on tensor calculus as well as a textbook or a reference for an intermediate-level course on differential geometry of curves and surfaces. The book is furnished with an index, extensive sets of exercises and many cross references, which are hyperlinked for the ebook users, to facilitate linking related concepts and sections. The book also contains a considerable number of 2D and 3D graphic illustrations to help the readers and users to visualize the ideas and understand the abstract concepts. We also provided an introductory chapter where the main concepts and techniques needed to understand the offered materials of differential geometry are outlined to make the book fairly self-contained and reduce the need for external references.
Additional file 3 of Energy delivery guided by indirect calorimetry in critically ill patients: a systematic review and meta-analysis
Creators: name: Duan, Jing-Yi
name: Zheng, Wen-He
name: Zhou, Hua
name: Xu, Yuan
name: Huang, Hui-Bin
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 3: Figure S1. Risk-of-bias graph: review authors' judgements about each risk-of-bias item presented as percentages across all included studies. Figure S2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Phytolith assemblages of Shorea robusta Gaertn. (Sal) from West Bengal part of the Bengal Basin, India and their implications in palaeoclimate reconstructions
Creators: name: Saikia, Korobi
name: Paruya, Dipak Kumar
name: Ghosh, Ruby
name: Bera, Subir
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Phytolith assemblages of Shorea robusta Gaertn. (Dipterocarpaceae), an important constituent of tropical deciduous/semi-evergreen forests were studied from six different districts of West Bengal, the western margin of the Bengal Basin. Since S. robusta grows in the tropical mixed dry to wet deciduous and semi-evergreen forests and can tolerate a wide variability in temperature and precipitation regimes, we aim to understand if these climatic parameters drive any changes in phytolith production pattern of the plant. Eleven different phytolith morphotypes retrieved from 13 plant specimens collected along the temperature and precipitation gradients show considerable variations among the specimens. Phytolith assemblages thus retrieved have been subjected to detrended correspondence analysis (DCA), which has helped to understand indirectly the influence of climatic parameter(s) on the phytolith production pattern of S. robusta, if any. Further, canonical correspondence analysis (CCA) performed on the phytolith data reveals how temperature and precipitation influence the variations in phytolith assemblages of the plant. The data provide a basis to understand how phytolith spectra of non-grass plants capture signal of climatic variability of any region and could be used in regional palaeoclimate reconstructions if recovered in fossil sediments.
Estatuto antropológico e limiares epistemológicos da educação social
Creators: name: Carvalho, Adalberto Dias
Publisher: name: Cadernos de Pedagogia Social
Year: 2019

description: O presente artigo desenvolve a temática do estatuto da educação social enquanto disciplina de confluência e síntese de vários saberes e enquanto prática de intervenção. Para o efeito questiona a sua relação com as ciências da educação e com a pedagogia social, a par das suas conexões com a ética e a política. Numa perspectiva essencialmente hermenêutica indaga-se ainda o complexo desafio que as situações-limite e o contrato social colocam à sociedade civil impondo que esta promova o exercício de uma cidadania responsável, dimensão em que a educação social tem um papel fundamental.
description: Cadernos de Pedagogia Social, n. 2 (2008): Educação e solidariedade social
Expanding the knowledge about Aflatunia ulmifolia (Franch.) Vassilcz. (Rosaceae), a rare forest species of Central Asia
Creators: name: Kirillov, Vitaliy
name: Stikhareva, Tamara
name: Ivashchenko, Anna
name: Sitpayeva, Gulnara
name: Kuliyev, Arstanbek
name: Serafimovich, Mariya
name: Daulenova, Meirzhan
name: Zholdasbayev, Mussa
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Aflatunia ulmifolia (Franch.) Vassilcz. is a rare, poorly studied species from the Rosaceae Juss family. Its natural distribution range is limited to Central Asia (Western Tien Shan, Pamir-Alay, Dzhungarskiy and Kirghiz Alatau). Information on the current state of natural plant communities with the participation of A. ulmifolia, the introduction potential, and the methods of conservation of the species is limited. The aim of our study was to improve information about A. ulmifolia, by verifying its current distribution range, both in natural habitats and in places where it is introduced, and analyze the major ecological, morphological and biological characteristics of the species. We produced the most up-to-date species distribution map showing both natural and introduced populations of A. ulmifolia. For the first time, we provide a comprehensive list of tree and shrub species co-occurring with A. ulmifolia in Tajikistan, Kyrgyzstan, and Kazakhstan. We present detailed information on the successful introduction of A. ulmifolia in nine European and Asian countries. Although the species is not of immediate conservation concern, it might become vulnerable to extinction if its distribution range continues to shrink because of anthropogenic impact and natural disturbances. We argue for the development of effective conservation strategies for A. ulmifolia in nature and for the creation of stable introduction populations of this species in botanical gardens and arboretums.
Towards further understanding of the persister bacterial populations in sputum during tuberculosis therapy
Creators: name: Decker, Jonathan
Publisher: name: University of Leicester
Year: 2025

description: IntroductionTwo Mycobacterium tuberculosis (Mtb) putative persister phenotypes were explored: Mtb positive for Lipid Bodies (LB+) and those described as that Differentially Culturable (DCMtb), due to their dependence on Mtb culture supernatant (CSN) for growth. Both phenotypes are associated with antimicrobial tolerance, are detected sputum and have been linked to inferior treatment responses. The enumeration of DCMtb in sputum and the influence of Nitric Oxide (NO) on the frequency of LB positive bacilli were studied and results related to patient treatment responses.MethodsFor NO / LB studies, Mtb isolates from The Gambia were used. LB+ frequencies in the sputa from which the Mtb strains were isolated, were known. To achieve amenable inter-strain comparisons a method of growth on agar to sub-confluency was established. This enabled harvesting without producing baseline new gene expression and exposure to NO followed by assessment of LB positivity and transcriptional analyses. For DCMtb studies most probable number (with and without CSN) and colony forming unit (CFU) assays were performed. Two sample sets were investigated, one from the MARK-TB biobank and a second collected prospectively from RIFASHORT, a high dose rifampicin trial. Results were linked to treatment responses.ResultsMtb strains were shown to express different LB+ frequencies at baseline and following NO exposure; frequencies correlated strongly ( r2 >0.9. p < 0.05) to those observed the cognate sputum samples. These stains also varied in their susceptibility to NO toxicity. In the MARK-TB study, high proportions of DCMtb in sputum samples taken at week 4 of treatment associated with unfavourable outcomes (OR 20.8). In RIFASHORT, reduction of DCMtb and CFUs were accelerated with high dose rifampicin compared to standard treatment.ConclusionMtb strains from different lineages show distinct responses to NO with respect to LBs, gene expression and susceptibility. These features potentially explain observed associations between sputum LB positivity and treatment responses. DCMtb frequencies in sputum from treated individuals associated with outcome in the MARK-TB study and with rifampicin dosage in RIFASHORT. These studies open up new opportunities to better understand differing responses to TB treatment and to enable prediction of outcomes without prolonged follow up.
Calcineurin-ERK Antagonism at the Nuclear Pore Complex Regulates Bi-Directional Nuclear Transport
Creators: name: McClure, Jaston
name: Cyert, Martha
Publisher: name: Stanford Digital Repository
Year: 2026
Subjects: calcineurin
calcium
neurodegeneration
immunosuppression
phosphorylation
nuclear pore complex (NPC)

description: Calcineurin, the ubiquitously expressed calcium/calmodulin-regulated protein phosphatase, is essential for many cellular processes, including T-cell activation. The dephosphorylation activity of this protein is effectively inhibited by the immunosuppressants cyclosporin A and tacrolimus (FK506). Clinical administration of these immunosuppressants leads to a myriad of adverse effects in non-target tissues, but the underlying causes of these adverse effects are still largely unknown. Recent work offers the foundation for a molecular-scale explanation of these adverse effects by demonstrating that calcineurin directly dephosphorylates multiple proteins in the nuclear pore complex (NPC), and that calcineurin inhibition alters protein transport through the NPC. These findings also suggest that the NPC is a site where calcium signaling takes place. To understand how calcineurin regulates nuclear transport, it is essential to determine whether it acts locally to exert control over nuclear import, nuclear export, or both processes. 

To pursue this inquiry, I employ NPC-tethered-calcineurin constructs to establish that calcineurin acts locally to regulate transport through the NPC in human cells. Next, I use light-inducible fluorescent reporters for nuclear import and export (LINuS and LEXY, respectively) to show that calcineurin inhibition decreases both import and export rates. These results suggest that calcineurin directly dephosphorylates nuclear pore proteins to promote bidirectional transport. In follow up experiments, I then show that calcineurin opposes ERK, the end effector of the MAPK pathway, to regulate nuclear transport rates. Finally, I demonstrate that calcineurin inhibition also causes importin-β and exportin-1 to mislocalize, thereby revealing a potential mechanism for the promotion of nuclear transport by calcineurin.

These findings offer exciting insights into how nuclear transport, a fundamental cellular process, is regulated. Intriguingly, both calcineurin inhibition and nuclear transport defects have been implicated in neurodegenerative phenotypes, suggesting that calcineurin-mediated nuclear transport may be crucial for understanding maladies such as Parkinson’s and Huntington’s disease.
title: Imagined publics - On the structural transformation of higher education and science. A post-Habermas perspective
Creators: name: Krücken, Georg
Publisher: name: Universität Kassel
Year: 2023
Subjects: subject: higher education
subject: imagined publics
subject: organization
subject: social sciences
subject: social transformation
subject: 100
subject: 300
subject: Hochschulbildung
subject: Habermas, Jürgen
subject: Sozialer Wandel

description: Gefördert im Rahmen des Projekts DEAL
PhD thesis defended at the University of Tokyo
Creators: name: Martins, Leonardo De Oliveira
Publisher: name: figshare
Year: 2017
Subjects: subject: Computational Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60309 Phylogeny and Comparative Analysis
subject: 60506 Virology

description: Recombinant DNA sequences can not be represented by a single topology since recombinant segments support distinct evolutionary histories. Existing methods for recombination detection can handle only a limited number of taxa, constraining the recombination analysis to cases where the phylogeny can be assumed known for the parental sequences. If the analysis is conducted independently for each putative recombinant sequence, potential recombinations between them are neglected. We newly developed a distance measure between unrooted topologies that closely resembles the number of recombinations. By introducing a prior distribution on these recombination distances, a Bayesian hierarchical model was devised to detect phylogenetic inconsistencies due to recombinations. On simulated datasets, our method correctly detected recombination break-points and the number of recombination events for each break-point. The procedure is robust to rate and transition:transversion heterogeneities for simulations with and without recombination. Applying the procedure to a genomic HIV-2 dataset, we found evidence for recombination hot-spots and intra-subtype recombination.
Additional file 1 of Investigating the effects of the main agronomic interventions on carabids and spiders in European arable fields: A systematic review protocol
Creators: name: Triquet, Coralie
name: Fabian, Yvonne
name: Jeanneret, Philippe
Publisher: name: figshare
Year: 2025
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Supplementary Material 1: ROSES report for systematic review protocol
Masters Thesis defended at the University of Sao Paulo
Creators: name: Martins, Leonardo De Oliveira
Publisher: name: figshare
Year: 2017
Subjects: subject: Computational Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60506 Virology

description: This project aimed the creation of a simulation environment for viral gene sequences, with special attention to HIV-1 genes, for the generation of simulated sequences within a known selective scenario [33]. An algorithm was created to ascribe the fitness of each sequence based on its similarity to the ancestral sequence. Several estimates of effective population size and test statistics for detecting selection based on sequence data and on phylogenies were compared under several selective models and population sizes, in order to stablish the power of each estimate.
title: 01_0350
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: Cadernos de Saúde, v. 2 n. Especial (2009): Línguas gestuais
title: Línguas gestuais
titleType: AlternativeTitle
Creators: name: Cadernos De Saúde
Publisher: name: Cadernos de Saúde
Year: 2009

description: Editorial...5-6 Brain mechanisms for sign language...7-12 Categorias fonológicas: um estudo sobre orientação manual em línguas gestuais antigas e novas...13-28 Imperativos análogos a raízes infinitivas: evidência das línguas de sinais americana e brasileira...29-35 Produção de gestos por ouvintes gestuantes iniciados: um olhar atento para a orientação manual...37-50 Oral language and sign language: possible approaches for deaf people’s language development...51-62 Lábios, leite, chocolate, laranja, etc.: um estudo sobre os nomes das cores em LSB...63-81 Juntando mais peças ao puzzle do léxico da LPG: três estudos pilotos...83-98 Estudos cognitivos em Língua Gestual Portuguesa: estudo de arte...99-104
Pedagogia Social: uma ciência, um saber profissional, uma filosofia de acção
Creators: name: Baptista, Isabel
Publisher: name: Cadernos de Pedagogia Social
Year: 2019

description: A disciplina científica que dá pelo nome de «pedagogia social» ocupa hoje um lugar fundamental no seio das ciências da educação, respondendo por um universo conceptual específico, alicerçado num património histórico próprio e num campo de problematização-acção de confirmada relevância na nossa contemporaneidade. É justamente em torno do conceito de pedagogia social, da sua história e da sua especificidade epistemológica que procuro reflectir neste texto, tentando evidenciar a pertinência socio-política desta área de conhecimento num quadro de renovação do «espaço público da educação», em conformidade com a utopia do humano preconizada pelas Nações Unidas para a sociedade do século XXI.
description: Cadernos de Pedagogia Social, n. 2 (2008): Educação e solidariedade social
Optimal Is Not Enough: Beyond Free Energy Perturbation Design Information
Creators: name: Pitman, Mary
name: Mobley, David L.
Publisher: name: Zenodo
Year: 2022
Subjects: binding free energy
LOMAP
optimal
graph theory
free energy perturbation
lead optimization
drug discovery

description: Changes to the statistical architecture of relative binding free energy (RBFE) perturbation maps dramatically improve the accuracy of affinity estimates. In perturbation maps, nodes represent ligands in a lead series of size n, and edges are alchemical transformations. For maximum certainty in predicted potencies, a design would include all edge combinations, or n choose 2 transformations. However, the computational cost to traverse all possible edges becomes prohibitive with increasing n. Experimental designs should therefore allocate resources intelligibly while preserving accuracy. The typical design process, such as that carried out by the open-source tool Lead Optimization Mapper, LOMAP, still relies on heuristic decisions for generating designs and parameters such as node selection and edge number are unexplored. To enable quantitative rigor in RBFE designs, I propose to modernize LOMAP, to find statistically optimal graphs over clusters of ligand series. Beyond optimal design generation, Optimal LOMAP will provide users with theoretically determined design space parameters and statistical tools for improved error correction. This poster on FEP design optimization was presented at OpenEye CUP XXI in March 2022.
title: saint Florent de Saumur
Creators: name: Centre De Recherches Historiques / Anthropologie Historique Du Long Moyen Âge
Publisher: name: EHESS (School for Advanced Studies in Social Sciences)
Year: 2019

description: Disciple de saint Martin de Tours, se retira en Anjou, au mont Glonne et fonda le monastère de Saint-Florent-Le-Vieil ; représenté dans une barque entre un ange et un démon ou chassant des serpents.
Distribution of maize ear rot in southwestern Ethiopia and its association with biophysical factors
Creators: name: Atnafu, Birhane
name: Abedeta, Chemeda
name: Temam, Bilal
name: Lemessa, Fikre
name: Chala, Alemayehu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified

description: A survey was carried out on 135 maize farms across nine districts and three zones of southwestern Ethiopia to determine the distribution of maize ear rot and its association with biophysical factors. Results revealed the prevalence of the disease across survey areas, albeit at varied intensities. Ear rot incidence and severity ranged from 41 to 54% and 31 to 40%, respectively. All maize grain samples collected from the survey area were positive for potentially toxigenic fungi genera, with Fusarium, Aspergillus, and Penicillium occurring at frequencies of 100%, 60%, and 58%, respectively. Higher ear rot incidence (>50%) had significant associations with zones, higher altitude, previous crop, lack of residue management, maize variety, and insect damage. The study indicates ear rot and kernel contamination by potentially toxigenic fungi is highly prevalent in southwestern Ethiopia and requires the use of certified seeds, residue management, shifting crops and reducing insect damage to manage the disease.
Additional file 1 of Relationships of residential distance to greenhouse floriculture and organophosphate, pyrethroid, and neonicotinoid urinary metabolite concentration in Ecuadorian Adolescents
Creators: name: Chronister, Briana N. C.
name: Kayser, Georgia L.
name: de la Cruz, Franklin
name: Suarez-Torres, Jose
name: Lopez-Paredes, Dolores
name: Gahagan, Sheila
name: Checkoway, Harvey
name: Jankowska, Marta M.
name: Suarez-Lopez, Jose R.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1.
On the benefts of insurance and disaster risk management integration for improved climate‑related natural catastrophe resilience
Creators: name: Sheehan, Barry
name: MULLINS, MARTIN
name: Shannon, Darren
name: MCCULLAGH, ORLA
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 350103
subject: Financial accounting

description: Insurance serves modern society and commerce by pooling risk to reduce the economic impact of disasters. Concurrently, Disaster Risk Management (DRM) scientists, responders and policymakers are co-developing proactive resilience and mitigation strategies with European citizens against accelerating climate-related natural catastrophes. The increasing frequency and severity of natural catastrophes exacerbates the insurance coverage gap by incurring even greater losses for (re)insurers, leading to higher premiums in exchange for cover or the withdrawal of services entirely. This paper presents a conceptual framework for cross-sectoral collaboration between the insurance and DRM communities towards open, transparent and optimised disaster risk management for all EU citizens and businesses. Furthermore, this research identifes key enabling technologies (satellite, drone, artifcial intelligence, blockchain) and novel risk transfer mechanisms with the potential to accelerate societal resilience to climate disasters through efective risk management. The study emphasises the critical role of the insurance industry in efective DRM and highlights where insurers could take a more active role across the temporal plane of a natural disaster by engaging in ex-ante interventions to protect those vulnerable to climate change-related risk.