cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Quelles sont les interventions infirmières probantes favorisant l’intégration des parents et le processus d’attachement entre les parents et leur enfant dans un service de soins intensifs de néonatologie ?
Creators: name: Duchoud, Sarah
name: Lambert, Sophie
Publisher: name: Unknown
Year: 0
Subjects: subject: Néonatologie
subject: Besoin
subject: Prématuré
subject: Parentalité
subject: Attachement
subject: Relations parents-enfants
subject: Partenariat
subject: Relation soignant-soigné
subject: Soins intensifs
subject: Recherche scientifique - sciences infirmières
subject: Revue de littérature

description: Après avoir analysé les articles sur la base des grilles BTEC, les auteurs pu en tirer les principaux résultats qui vont influer sur leur pratique infirmière. Ainsi, les besoins des parents vont être nommés et ils vont avoir un impact sur l’organisation des soins et sur les actions mises en oeuvre par les infirmières. Leur travail permettra donc de partager les soins à l’enfant, en fonction des compétences des parents. Les établissements de soins favorisent l’intégration des parents, car il a été prouvé que leur présence influence le bien-être du bébé. Un des principaux besoins énoncés par les parents est celui de la communication avec le personnel soignant. En effet, par cette méthode, les parents se sentent intégrés et reconnus. Ils perçoivent du soutien de la part des infirmières et savent qu’elles sont présentes et disponibles en cas de besoin. Il ressort aussi des différents articles que la présence des parents peut engendrer chez les soignants de la réticence, et ce à cause de la modification de l’environnement de travail.
RPM2, independently of its mitochondrial RNase P function, suppresses an ISP42 mutant defective in mitochondrial import and is essential for normal growth.
Creators: name: Martin, N C
name: Kassenbrock, C K
name: Sulo, P
name: Gao, G J
name: Groom, K R
name: Douglas, M G
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: RPM2 is identified here as a high-copy suppressor of isp42-3, a temperature-sensitive mutant allele of the mitochondrial protein import channel component, Isp42p. RPM2 already has an established role as a protein component of yeast mitochondrial RNase P, a ribonucleoprotein enzyme required for the 5' processing of mitochondrial precursor tRNAs. A relationship between mitochondrial tRNA processing and protein import is not readily apparent, and, indeed, the two functions can be separated. Truncation mutants lacking detectable RNase P activity still suppress the isp42-3 growth defect. Moreover, RPM2 is required for normal fermentative yeast growth, even though mitochondrial RNase P activity is not. The portion of RPM2 required for normal growth and suppression of isp42-3 is the same. We conclude that RPM2 is a multifunctional gene. We find Rpm2p to be a soluble protein of the mitochondrial matrix and discuss models to explain its suppression of isp42-3.
(:unas) unassigned
Creators: name: (:Unkn) Unknown
Publisher: name: Universita' degli Studi di Salerno
Year: 2024

description: Rising from a collaboration between Stanislavski and Brecht, this study explores how the contempo rary theater, in its textual and scenic structures, requires a new type of an actor who had to reme diate the gap between text and representation. To reflect the new type of “stage writing” and per formative forms, the actor’s body becomes a mean of expression, a blank page that captures all signs and translates them to the spectator by the medi ation of the “performed words” and gestures crossing it.
Selection of novel exon recognition elements from a pool of random sequences.
Creators: name: Kole, R
name: Tian, H
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: A 20-nucleotide sequence close to the 3' end of the internal exon of a model two-intron, three-exon pre-mRNA (DUP184 [Z. Dominski and R. Kole, J. Biol. Chem. 269:23590-23596, 1994]) was replaced by a random 20-mer, resulting in a pool of pre-mRNAs which, like the initial DUP184 construct, were spliced in vitro by a pathway leading to predominant skipping of the internal exon. The randomized pre-mRNAs were subjected to a selection protocol, resulting in a pool enriched in pre-mRNAs that efficiently included the internal exon. Isolation and sequencing of a number of clones corresponding to the selected pre-mRNAs showed that two classes of sequences were selected from the initial pool. Most abundant among these were sequences with purine tracts similar to those in the recently identified exon-splicing enhancers while a smaller class included sequences lacking discernible purine tracts within the 20-nucleotide region. Splicing of selected pre-mRNAs showed that the purine tracts vary in their ability to promote exon inclusion and, more important, that sequences lacking purine tracts stimulate inclusion of the internal exon as efficiently as their purine-rich counterparts. The latter result indicates the existence of a novel class of exon recognition sequences or splicing enhancers.
Spiritualité et santé ou la quête de sens chez les personnes hospitalisées dans un service de soins aigus
Creators: name: Chassot, Laure
name: Grisel, Magali
Publisher: name: Unknown
Year: 0
Subjects: subject: Spiritualité
subject: Soins
subject: Hospitalisation
subject: Santé
subject: Soins holistiques
subject: Besoins du patient
subject: Rôle infirmier
subject: Recherche scientifique - sciences infimières
subject: Revue de littérature

description: L'analyse de la littérature amène les auteurs à constater que la perception de la spiritualité est non seulement vaste, mais également floue. En effet, autant pour les soignants que pour les patients, cette notion semble être très différente pour chacun. Les infirmières savent qu’elles doivent prodiguer des soins selon une vision holistique, ce qui inclut la dimension spirituelle. Cependant, la grande confusion qui règne dans les services de soins au sujet de cette notion, rend difficile la relation entre les besoins spirituels des patients et le rôle des infirmières face à eux, et donc appellent l’aumônier pour y faire face. Cependant, les infirmières qui comprennent les expériences des patients arrivent mieux à les soutenir en leur consacrant du temps et de l’espace pour discuter de leurs besoins. Les bénéfices que procure la spiritualité pour le patient hospitalisé, son entourage, mais aussi pour toute l’équipe interdisciplinaire, sont incontournables. Elle améliore leur qualité de vie et leur permet de mieux vivre leur période de maladie.
Small Oscillations via Conservation of Energy in a Simple Static Equilibrium Problem
Creators: name: Troy, Tia
name: Reiner, Megan
name: Haugen, Andrew
name: Moore, Nathan T.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Physics Education (physics.ed-ph)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: The work describes an analogy-based small oscillations analysis of a standard static equilibrium lab problem. In addition to force analysis, a potential energy function for the system is developed, and by drawing out mathematical similarities to the simple harmonic oscillator, we are able to describe (and verify) the period of small oscillations about the static equilibrium state. The problem was developed and implemented in a standard University Physics course at Winona State University.
Anomalous spin polarization from turbulent color fields
Creators: name: Müller, Berndt
name: Yang, Di-Lun
Publisher: name: arXiv
Year: 2021
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the important, yet widely overlooked, role of gluons for spin transport with a connection to local parity violation in quark gluon plasmas. We employ the formalism of quantum kinetic theory to quarks in weakly coupled quantum chromodynamics to derive the source terms for quark spin polarization. These source terms involve parity-odd correlators of dynamically generated color fields in near-equilibrium quark gluon plasmas and give rise to locally fluctuating axial charge currents. Our results provide a possible explanation for the spin alignment of vector mesons measured in high-energy nuclear collisions.
description: 7 pages, 1 figure, corrected version post Erratum
Trends in Dwarf Early-Type Kinematics with Cluster-centric Radius Driven By Tidal Stirring
Creators: name: Benson, A. J.
name: Toloba, E.
name: Mayer, L.
name: Simon, J. D.
name: Guhathakurta, P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We model the dynamics of dwarf early-type galaxies in the Virgo cluster when subject to a variety of environmental processes. We focus on how these processes imprint trends in dynamical state (rotational vs. pressure support as measured by the $λ^*_{\rm Re/2}$ statistic) with projected distance from the cluster center, and compare these results to observational estimates. We find a large scatter in the gradient of $λ^*_{\rm Re/2}$ with projected radius. A statistical analysis shows that models with no environmental effects produce gradients as steep as those observed in none of the 100 cluster realizations we consider, while in a model incorporating tidal stirring by the cluster potential 34% of realizations produce gradients as steep as that observed. Our results suggest that tidal stirring may be the cause of the observed radial dependence of dwarf early-type dynamics in galaxy clusters.
description: 5 pages, accepted for publication in ApJ
Dans quelle mesure l’utilisation de la réflexologie par les infirmières tend-elle à diminuer la souffrance chez des personnes atteintes de maladies chroniques ?
Creators: name: Brogli, Samanta
name: Birraux, Sophie
Publisher: name: Unknown
Year: 0
Subjects: subject: Douleur
subject: Souffrance
subject: Relation soignant-soigné
subject: Réflexologie
subject: Rôle infirmier
subject: Qualité de vie
subject: Recherche scientifique - sciences infirmières
subject: Revue de littérature

description: Confrontés à des horizons de soins différents lors d’expériences de stage où la maladie et la douleur étaient très présentes, les auteurs se sont rendus compte que malgré un traitement antalgique instauré, bon nombre de patients subissaient encore une douleur persistante ou chronique. La revue de la littérature menée a démontré l’effet significatif de la réflexologie sur la douleur et l’anxiété. De plus, elle a de nombreux impacts positifs sur la qualité de vie, sur la sphère psychologique et sur le développement personnel des clients.
Trialing a corpus-based approach to preparation for courtroom interpreting with student interpreters
Creators: name: Kim, Mi Gyeong
Publisher: name: Macquarie University
Year: 2023
Subjects: classificationCode: 470404
subject: Corpus linguistics

description: Legal interpreting is viewed as one of the most challenging types of interpreting that occurs in a range of settings that present particular challenges for interpreters (Hale, 2007). Of these settings, courtroom interpreting is perhaps the most difficult because of its highly formalised and ritualised legal procedures. In addition, specialised language and terminology is used in the courtroom, with strategic use of language such as leading questions in cross-examination. Failing to accurately interpret legal terminology can have serious consequences for all parties involved (Wang and Grant, 2015). Given the importance of accurately interpreting legal language, interpreters prepare effectively to familiarise themselves with this specialised language. A corpus-based approach may be one method for effective preparation. Corpora can provide examples of legal terminology in context that allows interpreters to identify and comprehend specific legal terminology and everyday words used in a legal sense. This study aims to explore the effectiveness of a corpus-based approach to interpreting preparation, and interpreters’ perceptions of the experience. Student interpreter participants in the study were first tested on scenarios developed from court transcripts. They were then provided with a range of corpus materials and instructed in their use as a means of facilitating the acquisition of specialist terminology, and re-tested. The quantitative findings of this research suggest that the corpus-based preparation contributes to improvement of terminological accuracy, with positive feedback on the approach obtained by participant surveys.
Data science in industry - Designing a Net Zero energy system
Creators: name: Thomas, James
Publisher: name: Zenodo
Year: 2022

description: Reducing our CO₂ emissions to net zero is of global importance. In this talk at Strathmore Data Week 2022, I outline some of the challenges with using renewable energy for heating homes in the UK. I explore how data science can help with the design of future energy systems that could overcome these challenges, and at the same time unlock new energy markets in countries with solar potential.
Transcription-independent turnover of I kappa B alpha during monocyte adherence: implications for a translational component regulating I kappa B alpha/MAD-3 mRNA levels.
Creators: name: Haskill, J S
name: Mondal, K
name: Lofquist, A K
name: Morris, J S
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: We identified I kappa B alpha/MAD-3 as an immediate-early gene in human monocytes that is expressed in response to a variety of signals, including adhesion, lipopolysaccharide, and phorbol myristate acetate. Within 5 min of monocyte adhesion, the level of the I kappa B alpha protein is markedly diminished but is rapidly replaced in a cycloheximide-sensitive manner within 20 min. Accompanying the rapid turnover of the I kappa B alpha protein is simultaneous translocation of NF-kappa B-related transcription factors to nuclei of adhered monocytes. The demonstration that NF-kappa B can regulate I kappa B alpha/MAD-3 gene transcription in other cell types suggested that the rapid increase in steady-state I kappa B alpha/MAD-3 mRNA levels we observed within 30 min of monocyte adherence would result from NF-kappa B-dependent transcriptional stimulation of the I kappa B alpha/MAD-3 gene. Nuclear run-on analyses indicated that, instead, while several immediate-early cytokine genes, such as the interleukin 1 beta (IL-1 beta) gene, were transcriptionally activated during monocyte adhesion, the rate of I kappa B alpha/MAD-3 gene transcription remained constant. The adherence-dependent increase in I kappa B alpha/MAD-3 mRNA levels was also not a consequence of mRNA stabilization events. Interestingly, while increases in both IL-1 beta and I kappa B alpha/MAD-3 mRNA levels were detected in nuclei of adherent monocytes, cytoplasmic levels of IL-1 beta mRNA increased during adherence whereas those of I kappa B alpha/MAD-3 mRNA did not. Taken together, our data suggest that two interactive mechanisms regulate monocytic I kappa B alpha/MAD-3 mRNA levels. We propose that adherent monocytes regulate nuclear processing (or decay) of I kappa B alpha/MAD-3 mRNA, thereby increasing mRNA levels without stimulating I kappa B alpha/MAD-3 gene transcription. Moreover, since inhibition of protein synthesis leads to accumulation of I kappa B alpha/MAD-3 mRNA without stimulating I kappa B alpha/MAD-3 gene transcription, we suggest that low cytoplasmic levels of I kappa B alpha/MAD-3 mRNA are maintained by a translation-dependent degradation mechanism.
Semiclassical relativistic stars
Creators: name: Arrechea, Julio
name: Barceló, Carlos
name: Carballo-Rubio, Raúl
name: Garay, Luis J.
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present strong evidence that semiclassical gravity can give place to self-consistent ultracompact stars beyond the Buchdahl limit. We integrate the semiclassical equations of (spherically symmetric) stellar equilibrium for a constant-density classical fluid. The semiclassical contribution is modelled by a quantum massless scalar field in the only static vacuum state compatible with asymptotic flatness (Boulware vacuum). The Renormalized Stress-Energy Tensor (RSET) is firstly approximated by the analytic Polyakov approximation. This already reveals a crucial difference with respect to purely classical solutions: stars with compactness close to that of a black hole exhibit bounded pressures and curvatures up to a very small central core compared with the star radius. This suggests that a more refined approximation to the RSET at the core may give rise to strictly regular configurations. Following this suggestion, we prove that a minimal deformation of the Polyakov approximation inside the central core is sufficient to produce regular ultracompact stellar configurations.
description: 17 pages, 5 figures. Expanded main text significantly with extra details and explanations. Added a new Figure (Fig. 4), Figs. 2 and 3 replaced. Version to appear in Scientific Reports Gravitational Waves guest edited collection
Yeast MEK-dependent signal transduction: response thresholds and parameters affecting fidelity.
Creators: name: Printen, J A
name: Stevenson, B J
name: Errede, B
name: Matsumoto, K
name: Irie, K
name: Yashar, B
name: Sprague, G F
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: Ste7p and Mkk1p are MEK (MAPK/ERK kinase) family members that function in the mating and cell integrity signal transduction pathways in Saccharomyces cerevisiae. We selected STE7 and MKK1 mutations that stimulated their respective pathways in the absence of an inductive signal. Strikingly, serine-to-proline substitutions at analogous positions in Ste7p (position 368) and Mkk1p (position 386) were recovered by independent genetic screens. Such an outcome suggests that this substitution in other MEKs would exhibit similar properties. The Ste7p-P368 variant has higher basal enzymatic activity than Ste7p but still requires induction to reach full activation. The higher activity associated with Ste7p-P368 allows it to compensate for defects in the cell integrity pathway, but it does so only when it is overproduced or when Ste5p is missing. This behavior suggests that Ste5p, which has been proposed to be a tether for the kinases in the mating pathway, contributes to Ste7p specificity.
Elliptic and triangular flow of heavy flavor in heavy-ion collisions
Creators: name: Nahrgang, Marlene
name: Aichelin, Jörg
name: Bass, Steffen
name: Gossiaux, Pol Bernard
name: Werner, Klaus
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We investigate the elliptic and the triangular flow of heavy mesons in ultrarelativistic heavy-ion collisions at RHIC and the LHC. The dynamics of heavy quarks is coupled to the locally thermalized and fluid dynamically evolving quark-gluon plasma. The elliptic flow of $D$ mesons and the centrality dependence measured at the LHC is well reproduced for purely collisional and bremsstrahlung interactions. Due to the event-by-event fluctuating initial conditions from the EPOS2 model, the $D$ meson triangular flow is predicted to be nonzero at $\sqrt{s}=200$ GeV and $\sqrt{s}=2.76$ TeV. We study the centrality dependence and quantify the contributions stemming from flow of the light bulk event and the hadronization process. The flow coefficients as response to the initial eccentricities behave differently for heavy mesons than for light hadrons due to their inertia. Higher-order flow coefficients of heavy flavor become important in order to quantify the degree of thermalization.
Quelles sont les caractéristiques du réconfort lorsqu’un patient vit une situation d’inconfort et qu’est-ce qui rend ce soin professionnel ?
Creators: name: Bloch-Keller, Joëlle
name: Maillefer, Stéphanie
Publisher: name: Unknown
Year: 0
Subjects: subject: Relation soignant-soigné
subject: Accompagnement
subject: Souffrance
subject: Réconfort
subject: Recherche scientifique - Sciences infirmières
subject: Revue de littérature

description: Il existe une relation significative entre un état de mal-être, une difficulté éprouvée et le besoin d’un soulagement. D’ailleurs il est courant de vouloir réconforter un proche ayant vécu une situation difficile ou de l’encourager après une expérience douloureuse. Les infirmières accompagnent quotidiennement des patients rencontrant de telles situations, soit parce qu’ils ont appris une mauvaise nouvelle, soit parce qu’il s’apprête à vivre une situation inconnue pour eux ou encore, soit parce qu’ils ressentent de l’inconfort. C’est dans ces moments particuliers que le réconfort prend tout son sens et sa place dans les interventions infirmières.
Promotion d’une pratique clinique en harmonie avec l’expérience des parents d’enfants hospitalisés aux soins intensifs de pédiatrie
Creators: name: Subilia, Raphaëlle
name: Vachoux, Stéphanie
Publisher: name: Unknown
Year: 0
Subjects: subject: Hospitalisation
subject: Enfant
subject: Soins intensifs
subject: Pédiatrie
subject: Témoignage
subject: Partenariat
subject: Role infirmier
subject: Relation soignant-famille
subject: Recherche scientifique - sciences infirmières
subject: Revue de littérature

description: Ce travail s’intéresse à ce que les parents racontent de leur expérience lorsque leur enfant est hospitalisé aux soins intensifs de pédiatrie. Ce questionnement est issu d’un stage dans ce contexte précis, où les infirmières rencontrées exprimaient de la difficulté à comprendre réellement ce que les parents vivaient de manière intime et la raison de certaines de leurs réactions. Comment l’infirmière peut-elle adapter son savoir, savoir-être et savoir-faire au quotidien face à ce que vivent les parents ? Les auteurs se sont basé sur des résultats de recherches scientifiques enrichissant et rendant fiables les savoirs cliniques. Les huit articles issus dans les bases de données Medline, Cinhal, Ovid et Health Source, rendent compte du phénomène sous trois angles différents : 1. L’expérience brute des parents lors de l’hospitalisation de leur enfant 2. La manière dont les parents vivent leur relation avec l’infirmière 3. Ce que vivent les parents sur le long terme, c’est-à-dire une année après l’événement Ces trois approches ont permis de dégager quelques résultats surprenants. Par exemple, il semblerait que la mère soit capable intuitivement d’évaluer la gravité de l’état de santé de son enfant, ce qui rend son évaluation indispensable à l’infirmière au quotidien. Une autre découverte des auteurs réside dans le fait que l’expérience des parents reste vive encore une année après, et qu’au vu du lien très fort qui s’établit avec les soins intensifs de pédiatrie, il serait tout à fait intéressant que les infirmières des soins intensifs assument leur suivi sur le long terme si la demande existe. D’autres résultats ont permis de déduire des recommandations pour une pratique clinique en harmonie avec ce que vivent les parents.
title: Le rôle infirmier dans la promotion de l'attachement en néonatologie
title: comment peut-on utiliser les stratégies infirmières optimisant le lien d'attachement entre une mère et son enfant prématuré dans un service de soins intensifs de néonatologie ?
titleType: Subtitle
Creators: name: Nydegger, Laura
name: Samson, Tatiana
Publisher: name: Unknown
Year: 0
Subjects: subject: Attachement
subject: Relation mère-enfant
subject: Prématuré
subject: Partenariat
subject: Relation soignant-soigné
subject: Compétence
subject: Maternité
subject: Néonatologie
subject: Recherche scientifique- sciences infirmières
subject: Revue de littérature

description: A travers les articles consultés, plusieurs stratégies ont été relevées comme susceptibles d’influencer le processus d'attachement entre une mère et son enfant prématuré. Tout d'abord, la promotion de la proximité physique, puis l'information régulière à la mère quant au quotidien de son enfant. Le partenariat entre la mère et l'infirmière crée une relation qui permet notamment à l'infirmière de renforcer les compétences maternelles. Ces interventions infirmières ont un impact sur le processus d'attachement. De plus, la connaissance des comportements d'attachement permet de se rendre compte de l'évolution du processus d'attachement.
title: Enfant, famille et diabète
title: quelle éducation à la santé dans un contexte d'interculturalité ?
titleType: Subtitle
Creators: name: Muriset, Marie
name: Studer, Danaé
Publisher: name: Unknown
Year: 0
Subjects: subject: Santé
subject: Enfant
subject: Diabète
subject: Education pour la santé
subject: Education du patient
subject: Interculturalité
subject: Rôle infirmier
subject: Migrant
subject: Soins infirmiers interculturels
subject: Recherche scientifique - Sciences infirmières
subject: Revue de littérature

description: Les articles choisis et analysés pour cette revue de littérature permettent de retenir certains points importants. Le fait de provenir d'une minorité ethnique est souvent décrit comme un facteur de risque dans le contrôle du diabète. Diverses barrières telles que les différences linguistiques, les croyances culturelles sur la santé ou encore les désavantages économiques et sociaux sont des dimensions importantes à considérer dans l'éducation à la santé des familles migrantes. Des interprètes devraient être présents dans certaines situations afin d'améliorer la compréhension mutuelle, et du matériel éducatif adapté devrait être créé. La formation interculturelle est mise en avant et décrite comme importante pour les soignants dans le contexte de l'interculturalité (...). Ce travail a permis aux auteurs de prendre conscience du caractère primordial du rôle propre infirmier auprès d'enfants diabétiques et de leur famille, dans un contexte d'interculturalité.
Common factors direct transcription through the proximal sequence elements (PSEs) of the embryonic sea urchin U1, U2, and U6 genes despite minimal similarity among the PSEs.
Creators: name: Marzluff, W F
name: Li, J M
name: Haberman, R P
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: The proximal sequence element (PSE) for the sea urchin U6 small nuclear RNA gene has been defined. The most critical nucleotides for expression, located 61 to 64 nucleotides (nt) from the transcription start site, are 4 nt, AACT, at the 5' end of the PSE. Two nucleotide mutations in this region abolish transcription of the sea urchin U6 gene in vitro. The same two nucleotide mutations greatly reduce the binding of specific factors detected by an electrophoretic mobility shift assay. There is also a conserved AC dinucleotide 57 nt from the start site of the sea urchin U1 and U2 PSEs. The sea urchin U1 and U2 PSEs were substituted for the sea urchin U6 PSE, with the conserved AC sequences aligned with those of the U6 PSE. Both of these genes were expressed at levels higher than those observed with the wild-type U6 gene. Similar complexes are formed on the U1 and U2 PSEs, and formation of the complexes is inhibited efficiently by the U6 PSE. In addition, the E-box sequence present upstream of the PSE enhances U6 transcription from both the U1 and U2 PSEs. Finally, depletion of a nuclear extract with a DNA affinity column containing the U6 PSE sequence reduces expression of the U6 genes driven by the U6, U1, or U2 PSE but does not affect expression of the 5S rRNA gene. These data support the possibility that the same factor(s) interacts with the PSE sequences of the U1, U2, and U6 small nuclear RNA genes expressed in early sea urchin embryogenesis.
title: Douleur & Culture
title: lorsque deux mondes se rencontrent
titleType: Subtitle
Creators: name: Riera, Lucie
name: Meylan, Karelle
Publisher: name: Unknown
Year: 0
Subjects: subject: Douleur
subject: Culture
subject: Politique sanitaire
subject: Rôle infirmier
subject: Respect
subject: Valeurs
subject: Recherche scientifique - Sciences infirmières
subject: Revue de littérature

description: Cette revue de littérature a pour intention d’explorer l’influence des interactions entre la culture de l’infirmière et celle du patient dans l’appréciation de la souffrance de ce dernier. C’est en enrichissant cette réflexion par la lecture et l’analyse de sept articles scientifiques que les auteurs de ce travail arrivent, entre autre, à la conclusion suivante: pour une prise en soins de la douleur culturellement compétente, les infirmières devraient se considérer comme les médiateurs entre le système de santé et le patient, avec pour mission d’assurer le respect des valeurs culturelles de ce dernier.
Electroelastic metasurface with resonant piezoelectric shunts for tunable wavefront control
Creators: name: Lin, Zhenkun
name: Tol, Serife
Publisher: name: arXiv
Year: 2022
Subjects: subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: This study presents a tunable phase-modulated metasurface composed of periodically distributed piezoelectric patches with resonant-type shunt circuits. The fully coupled electromechanical model is established to study the transmission characteristics of the metasurface unit and validated through numerical and experimental studies. Based on the analysis of the metasurface unit, we first explore the performance of electroelastic metasurface with single-resonant shunts and then extend its capability with multi-resonant shunts. By only tuning the electric loads in the shunt circuits, we utilize the proposed metasurface to accomplish wave deflection and wave focusing of A0 mode Lamb waves at different angles and focal points, respectively.
description: 8 figures
Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase.
Creators: name: Burchert, A
name: Liu, E T
name: Jin, Y
name: Varnum, B
name: Quilliam, L A
name: Der, C
name: Spizz, G
name: McCloskey, P
name: Fridell, Y W
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: To understand the mechanism of Axl signaling, we have initiated studies to delineate downstream components in interleukin-3-dependent 32D cells by using a chimeric receptor containing the recombinant epidermal growth factor (EGF) receptor extracellular and transmembrane domains and the Axl kinase domain (EAK [for EGF receptor-Axl kinase]). We have previously shown that upon exogenous EGF stimulation, 32D-EAK cells are capable of proliferation in the absence of interleukin-3. With this system, we determined that EAK-induced cell survival and mitogenesis are dependent upon the Ras/extracellular-signal-regulated protein kinase (ERK) cascade. Although the phosphatidylinositol-3 kinase pathway is activated upon EAK signaling, it appears to be dispensable for the biological actions of the Axl kinase. Furthermore, we demonstrated that different threshold levels of Ras/ERK activation are needed to induce a block to apoptosis or proliferation in 32D cells. Recently, we have identified an Axl ligand, GAS6. Surprisingly, GAS6-stimulated 32D-Axl cells exhibited no blockage to apoptosis or mitogenic response which is correlated with the absence of Ras/ERK activation. Taken together, these data suggest that different extracellular domains dramatically alter the intracellular response of the Axl kinase. Furthermore, our data suggest that the GAS6-Axl interaction does not induce mitogenesis and that its exact role remains to be determined.
Combinatorial cohomology of the space of long knots
Creators: name: Mortier, Arnaud
Publisher: name: arXiv
Year: 2014
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: The motivation of this work is to define cohomology classes in the space of knots that are both easy to find and to evaluate, by reducing the problem to simple linear algebra. We achieve this goal by defining a combinatorial graded cochain complex, such that the elements of an explicit submodule in the cohomology define algebraic intersections with some "geometrically simple" strata in the space of knots. Such strata are endowed with explicit co-orientations, that are canonical in some sense. The combinatorial tools involved are natural generalisations (degeneracies) of usual methods using arrow diagrams.
description: 20p. 9 figs
Visual Landmark Recognition from Internet Photo Collections: A Large-Scale Evaluation
Creators: name: Weyand, Tobias
name: Leibe, Bastian
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The task of a visual landmark recognition system is to identify photographed buildings or objects in query photos and to provide the user with relevant information on them. With their increasing coverage of the world's landmark buildings and objects, Internet photo collections are now being used as a source for building such systems in a fully automatic fashion. This process typically consists of three steps: clustering large amounts of images by the objects they depict; determining object names from user-provided tags; and building a robust, compact, and efficient recognition index. To this date, however, there is little empirical information on how well current approaches for those steps perform in a large-scale open-set mining and recognition task. Furthermore, there is little empirical information on how recognition performance varies for different types of landmark objects and where there is still potential for improvement. With this paper, we intend to fill these gaps. Using a dataset of 500k images from Paris, we analyze each component of the landmark recognition pipeline in order to answer the following questions: How many and what kinds of objects can be discovered automatically? How can we best use the resulting image clusters to recognize the object in a query? How can the object be efficiently represented in memory for recognition? How reliably can semantic information be extracted? And finally: What are the limiting factors in the resulting pipeline from query to semantics? We evaluate how different choices of methods and parameters for the individual pipeline steps affect overall system performance and examine their effects for different query categories such as buildings, paintings or sculptures.
ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs.
Creators: name: Lamerdin, J E
name: Zhou, Z Q
name: Hwang, M
name: Reardon, J T
name: Thelen, M P
name: Thompson, L H
name: Sancar, A
name: Walter, C A
name: Brookman, K W
name: Parris, C N
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: ERCC4 is an essential human gene in the nucleotide excision repair (NER) pathway, which is responsible for removing UV-C photoproducts and bulky adducts from DNA. Among the NER genes, ERCC4 and ERCC1 are also uniquely involved in removing DNA interstrand cross-linking damage. The ERCC1-ERCC4 heterodimer, like the homologous Rad10-Rad1 complex, was recently found to possess an endonucleolytic activity that incises on the 5' side of damage. The ERCC4 gene, assigned to chromosome 16p13.1-p13.2, was previously isolated by using a chromosome 16 cosmid library. It corrects the defect in Chinese hamster ovary (CHO) mutants of NER complementation group 4 and is implicated in complementation group F of the human disorder xeroderma pigmentosum. We describe the ERCC4 gene structure and functional cDNA sequence encoding a 916-amino-acid protein (104 kDa), which has substantial homology with the eukaryotic DNA repair and recombination proteins MEI-9 (Drosophila melanogaster), Rad16 (Schizosaccharomyces pombe), and Rad1 (Saccharomyces cerevisiae). ERCC4 cDNA efficiently corrected mutants in rodent NER complementation groups 4 and 11, showing the equivalence of these groups, and ERCC4 protein levels were reduced in mutants of both groups. In cells of an XP-F patient, the ERCC4 protein level was reduced to less than 5%, consistent with XPF being the ERCC4 gene. The considerable identity (40%) between ERCC4 and MEI-9 suggests a possible involvement of ERCC4 in meiosis. In baboon tissues, ERCC4 was expressed weakly and was not significantly higher in testis than in nonmeiotic tissues.
Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae.
Creators: name: Harkins, H A
name: Zahner, J E
name: Pringle, J R
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1996

description: Previous analysis of the bipolar budding pattern of Saccharomyces cerevisiae has suggested that it depends on persistent positional signals that mark the region of the division site and the tip of the distal pole on a newborn daughter cell, as well as each previous division site on a mother cell. In an attempt to identify genes encoding components of these signals or proteins involved in positioning or responding to them, we identified 11 mutants with defects in bipolar but not in axial budding. Five mutants displaying a bipolar budding-specific randomization of budding pattern had mutations in four previously known genes (BUD2, BUD5, SPA2, and BNI1) and one novel gene (BUD6), respectively. As Bud2p and Bud5p are known to be required for both the axial and bipolar budding patterns, the alleles identified here probably encode proteins that have lost their ability to interact with the bipolar positional signals but have retained their ability to interact with the distinct positional signal used in axial budding. The function of Spa2p is not known, but previous work has shown that its intracellular localization is similar to that postulated for the bipolar positional signals. BNI1 was originally identified on the basis of genetic interaction with CDC12, which encodes one of the neck-filament-associated septin proteins, suggesting that these proteins may be involved in positioning the bipolar signals. One mutant with a heterogeneous budding pattern defines a second novel gene (BUD7). Two mutants budding almost exclusively from the proximal pole carry mutations in a fourth novel gene (BUD9). A bud8 bud9 double mutant also buds almost exclusively from the proximal pole, suggesting that Bud9p is involved in positioning the proximal pole signal rather than being itself a component of this signal.
Spatially-Modulated Silicon Interface Energetics via Hydrogen Plasma-Assisted Atomic Layer Deposition of Ultrathin Alumina
Creators: name: Henning, Alex
name: Bartl, Johannes D.
name: Wolz, Lukas
name: Christis, Maximilian
name: Rauh, Felix
name: Bissolo, Michele
name: Grünleitner, Theresa
name: Eichhorn, Johanna
name: Zeller, Patrick
name: Amati, Matteo
name: Gregoratti, Luca
name: Finley, Jonathan J.
name: Rieger, Bernhard
name: Stutzmann, Martin
name: Sharp, Ian D.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: Atomic layer deposition (ALD) is a key technique for the continued scaling of semiconductor devices, which increasingly relies on reproducible and scalable processes for interface manipulation of 3D structured surfaces on the atomic scale. While ALD allows the synthesis of conformal films at low temperature with utmost control over the thickness, atomically-defined closed coatings and surface modifications are still extremely difficult to achieve because of three-dimensional growth during nucleation. Here, we present a route towards sub-nanometer thin and continuous aluminum oxide (AlOx) coatings on silicon (Si) substrates for the spatial control of the surface charge density and interface energetics. We use trimethylaluminum (TMA) in combination with remote hydrogen plasma instead of a gas-phase oxidant for the transformation of silicon oxide into alumina (AlOx). During the initial ALD cycles, TMA reacts with the surface oxide (SiO2) on silicon until there is a saturation of bindings sites, after which the oxygen from the underlying surface oxide is consumed, thereby transforming the silicon oxide into Si capped with AlOx. Depending on the number of ALD cycles, the SiO2 can be partially or fully transformed, which we exploit to create sub-nanometer thin and continuous AlOx layers deposited in selected regions defined by lithographic patterning. The resulting patterned surfaces are characterized by lateral AlOx/SiO2 interfaces possessing step heights as small as 0.3 nm and surface potential steps in excess of 0.4 V. In addition, the introduction of fixed negative charges of $9 \times 10^{12}$ cm$^{-2}$ enables modulation of the surface band bending, which is relevant to the field-effect passivation of Si and low-impedance charge transfer across contact interfaces.
description: main manuscript: 16 pages, 5 figures; supporting information: 10 pages, 7 figures
En quoi les activités non-structurées partagées entre les infirmier-ères et les patients en psychiatrie sont-elles thérapeutiques ?
Creators: name: Lugrin, Joëlle
name: Gillioz, Frédéric
Publisher: name: Unknown
Year: 0
Subjects: subject: Psychiatrie
subject: Qualité de vie
subject: Sport
subject: Musique
subject: Estime de soi
subject: Relation thérapeutique
subject: Relation soignant-soigné
subject: Rôle infirmier
subject: Recherche scientifique - sciences infirmières
subject: Revue de littérature

description: A partir d’un questionnement personnel et professionnel fondé sur les cadres théoriques de Peplau (1988) et Gunderson (1978), ce travail explique comment adapter la pratique infirmière en psychiatrie dans la perspective d’aider la personne à interagir de manière saine avec son environnement. Il souligne de quelle manière les approches informelles et les attitudes thérapeutiques infirmières permettent aux patients en psychiatrie d’améliorer leur qualité de vie. Pour cela, ce travail définit en quoi les activités socio-thérapeutiques offertes par les infirmières telles que les sports d’équipe, la musique et les relations, sont bénéfiques dans l’évolution positive d’une personne souffrant d’un trouble psychique. Ces activités non-structurées faisant partie de l’aspect informel du travail infirmier, au sein de diverses institutions de soin, servent à compléter les approches traditionnelles en proposant un suivi du patient dans son quotidien. Il est important de définir les aspects de la qualité de vie que les patients veulent améliorer, dans le but d’adapter les interventions infirmières selon leurs besoins et le sens qu’ils peuvent y trouver. L’attitude infirmière basée sur la mutualité avec le patient permet de renforcer l’empowerment, l’estime de soi et les compétences sociales. Il est en outre important d’adapter cette approche en fonction du contexte de soin en offrant un environnement permettant aux patients d’améliorer leur qualité de vie en travaillant sur leur quotidien. Pour promouvoir la reconnaissance de la totalité du travail infirmier, il est nécessaire d’insister sur l’approche informelle des infirmier-ères dans la formation initiale ainsi que de poursuivre les recherches. Ceci leur permet de défendre leur travail au niveau politique et économique en apportant des arguments basés sur des données scientifiques.
Integrable and superintegrable systems associated with multi-sums of products
Creators: name: van der Kamp, Peter H.
name: Kouloukas, Theodoros E.
name: Quispel, G. R. W.
name: Tran, Dinh T.
name: Vanhaecke, Pol
Publisher: name: arXiv
Year: 2014
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We construct and study certain Liouville integrable, superintegrable, and non-commutative integrable systems, which are associated with multi-sums of products.
description: 26 pages, submitted to Proceedings of the royal society A
Comments on epsilon expansion of the O$(N)$ model with boundary
Creators: name: Nishioka, Tatsuma
name: Okuyama, Yoshitaka
name: Shimamori, Soichiro
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The O$(N)$ vector model in the presence of a boundary has a non-trivial fixed point in $(4-ε)$ dimensions and exhibits critical behaviors described by boundary conformal field theory. The spectrum of boundary operators is investigated at the leading order in the $ε$-expansion by diagrammatic and axiomatic approaches. In the latter, we extend the framework of Rychkov and Tan for the bulk theory to the case with a boundary and calculate the conformal dimensions of boundary composite operators with attention to the analyticity of correlation functions. In both approaches, we obtain consistent results.
description: 27 pages, 1 figure; v2: published version
Comment optimiser la prise en charge de la douleur, à travers l’évaluation, chez les personnes âgées atteintes de démence, en institution ?
Creators: name: Hentzler, Floriane
name: Itema Mbuebue Mukanya, Nelly
Publisher: name: Unknown
Year: 0
Subjects: subject: Personne âgée
subject: Douleur
subject: Evaluation
subject: Echelle d'évaluation
subject: Démence
subject: Recherche scientifique - Sciences infirmières
subject: Revue de littérature

description: Confrontés aux personnes âgées durant les stages, les auteurs ont constaté que la douleur de celles-ci n’était pas toujours reconnue par les professionnels et n’était pas correctement soulagée. Les auteurs ont posé l’hypothèse qu’il pouvait s’agir d’un manque ou d’une évaluation incorrecte de la douleur chez ces personnes. Le but de cette revue de littérature est donc de trouver et mettre à la disposition des soignants des outils d’évaluation de la douleur disponibles, valables, fiables, utiles pour la clinique, francophones, faciles à utiliser et adaptés à cette population. Résultats : - L’autoévaluation reste valable jusqu’à un degré assez élevé de troubles cognitifs. Néanmoins, avec la sévérité de ces troubles, cette évaluation devrait être complétée ou remplacée par l’hétéroévaluation. - A l’issue de nos recherches, 3 échelles francophones ont été retenues, répondant aux critères de validité, fiabilité et utilité clinique : l’ECPA-2, Doloplus-2, PACSLAC-F. Ces 3 échelles peuvent être utilisées en pratique, moyennant des études supplémentaires.