cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Systemically released volatiles from Solena amplexicaulis plant leaves with color cues influencing attraction of a generalist insect herbivore
Creators: name: Amarnath Karmakar
name: Saubhik Mitra
name: Anandamay Barik
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: Solena amplexicaulis (Lam.) Gandhi (Cucurbitaceae) is a promising vegetable in Southeast Asia. Infestation of Aulacophora foveicollis Lucas (Coleoptera: Chrysomelidae) adults on leaves of the crop plant causes death of the plant and reduces crop production. Currently, growers are applying insecticides to control this pest, which are harmful to health and environment. Hence, an attempt has been made to find out allelochemicals from leaves attracting the insect, which might be used for ecofriendly pest management program. The emission of volatiles was detected from undamaged leaves of herbivore-induced plants after 24 h and 120 h of continuous females feeding on lower leaves of the same plants by GC-MS and GC-FID analysis. The insect showed attraction to systemically released volatiles from herbivore-induced plants against unharmed plants in Y-shaped glass tube olfactometer bioassays. The insect was attracted to a synthetic blend of 1.2 µg linalool oxide + 3.2 µg nonanal + 1.5 µg trans-2-nonenal dissolved in 20 µL CH2Cl2 in olfactometer and wind tunnel bioassays, and hence, this blend could be used in development of baited traps in pest management strategies.
Using machine learning to predict health-related quality of life outcomes in patients with low grade glioma, meningioma, and acoustic neuroma
Creators: name: Karri, R
name: Chen, Yi-Ping Phoebe
name: Drummond, KJ
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 320299
subject: Clinical sciences not elsewhere classified

description: Background Predicting reduced health-related quality of life (HRQoL) after resection of a benign or low-grade brain tumour provides the opportunity for early intervention, and targeted expenditure of scarce supportive care resources. We aimed to develop, and evaluate the performance of, machine learning (ML) algorithms to predict HRQoL outcomes in this patient group. Methods Using a large prospective dataset of HRQoL outcomes in patients surgically treated for low grade glioma, acoustic neuroma and meningioma, we investigated the capability of ML to predict a) HRQoL-impacting symptoms persisting between 12 and 60 months from tumour resection and b) a decline in global HRQoL by more than the minimum clinically important difference below a normative population mean within 12 and 60 months after resection. Ten-fold cross-validation was used to measure the area under the receiver operating characteristic curve (AUC), area under the precision-recall curve (PR-AUC), sensitivity, and specificity of models. Six ML algorithms were explored per outcome: Random Forest Classifier, Decision Tree Classifier, Logistic Regression, K Neighbours Classifier, Support Vector Machine, and Gradient Boosting Machine. Results The final cohort included 262 patients. Outcome measures for which AUC>0.9 were Appetite loss, Constipation, Nausea and vomiting, Diarrhoea, Dyspnoea and Fatigue. AUC was between 0.8 and 0.9 for global HRQoL and Financial difficulty. Pain and Insomnia achieved AUCs below 0.8. PR-AUCs were similar overall to the AUC of each respective classifier. Conclusions ML algorithms based on routine demographic and perioperative data show promise in their ability to predict HRQoL outcomes in patients with low grade and benign brain tumours between 12 and 60 months after surgery.
Suppressor of TCR signaling-2 (STS-2) suppresses arthritis development in mice
Creators: name: Okabe, Namiko
name: Ohmura, Koichiro
name: Katayama, Masaki
name: Akizuki, Shuji
name: Carpino, Nick
name: Murakami, Kosaku
name: Nakashima, Ran
name: Motomu Hashimoto
name: Imura, Yoshitaka
name: Yoshifuji, Hajime
name: Tanaka, Masao
name: Tsuneyo Mimori
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Hematology

description: Objectives: Suppressor of TCR signaling-2 (STS-2) is one of the RA susceptibility genes identified in genome-wide association studies (GWAS). We tried to verify the involvement of STS-2 on the development of autoimmune arthritis in a mouse model. Methods: STS-2 knock-out (KO) and wild type (WT) mice were immunized with chicken type II collagen (CII). For CD4+ helper T cell (Th) subset analysis, intracellular cytokines in splenocytes and lymph node cells were stained and analyzed by flow cytometry. Regulatory T cell (Treg) function was analyzed by co-culturing effector CD4+T cells and Tregs collected from non-immunized mice. Results: CII-immunized STS-2 KO mice developed arthritis more frequently than WT mice. Although the T cell activation profile and Th subset in spleen and LNs were similar between STS-2 KO and WT mice, STS-2 KO mice showed increased IL-2-producing CD4+T cells in spleen when compared with WT mice. Accordingly, STS-2 KO CD4+T cells promoted IL-2 production by TCR stimulation. However, STS-2 KO Tregs normally suppressed T cell proliferation. Conclusion: We proved that STS-2 is involved in the arthritis development by collagen-induced arthritis. Higher IL-2 production from STS-2 KO T cells is suggested to have a main pathogenic role in arthritis development.
Facile synthetic route to benzo[c]chromenones and thieno[2,3-c]chromenones
Creators: name: Shyyka, Olga Ya.
name: Martyak, Roman L.
name: Tupychak, Mykola A.
name: Nazariy T. Pokhodylo
name: Obushak, Mykola D.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Convenient two-step procedure for the synthesis of fused chromenone derivatives was developed. Reduction of the obtained in the Meerwein arylation reaction aryl- and thienylquinones allowed to construct 6H-benzo[c]chromene-6-ones and 4H-thieno[2,3-c]chromen-4-one in a more cost- and time-effective manner in comparison with already known methods. The obtained products have provided a new entry to chromenone derivatives.
Empirical Evaluation of Inflorescences’ Morphological Attributes for Yield Optimization of Medicinal Cannabis Cultivars
Creators: name: Naim-Feil, Erez
name: Breen, EJ
name: Pembleton, LW
name: Spooner, LE
name: Spangenberg, German
name: Cogan, Noel
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 310899
subject: Plant biology not elsewhere classified

description: In recent decades with the reacknowledgment of the medicinal properties of Cannabis sativa L. (cannabis) plants, there is an increased demand for high performing cultivars that can deliver quality products for various applications. However, scientific knowledge that can facilitate the generation of advanced cannabis cultivars is scarce. In order to improve cannabis breeding and optimize cultivation techniques, the current study aimed to examine the morphological attributes of cannabis inflorescences using novel image analysis practices. The investigated plant population comprises 478 plants ascribed to 119 genotypes of high−THC or blended THC−CBD ratio that was cultivated under a controlled environment facility. Following harvest, all plants were manually processed and an image of the trimmed and refined inflorescences extracted from each plant was captured. Image analysis was then performed using in-house custom-made software which extracted 8 morphological features (such as size, shape and perimeter) for each of the 127,000 extracted inflorescences. Our findings suggest that environmental factors play an important role in the determination of inflorescences’ morphology. Therefore, further studies that focus on genotype X environment interactions are required in order to generate inflorescences with desired characteristics. An examination of the intra-plant inflorescences weight distribution revealed that processing 75% of the plant’s largest inflorescences will gain 90% of its overall yield weight. Therefore, for the optimization of post-harvest tasks, it is suggested to evaluate if the benefits from extracting and processing the plant’s smaller inflorescences outweigh its operational costs. To advance selection efficacy for breeding purposes, a prediction equation for forecasting the plant’s production biomass through width measurements of specific inflorescences, formed under the current experimental methodology, was generated. Thus, it is anticipated that findings from the current study will contribute to the field of medicinal cannabis by improving targeted breeding programs, advancing crop productivity and enhancing the efficacy of post-harvest procedures.
title: ADCO, Abbaye de Cîteaux, 'Transcrits des titres de la layette marquée QQ, 1er cartable, liasses 1, 2 et 3' / Cartulaire d'Ouges (XVIIIe siècle, 2e moitié), Cart. 196 (11 H 938), f. 0074
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Abbaye de Cîteaux, 'Transcrits des titres de la layette marquée QQ, 1er cartable, liasses 1, 2 et 3' / Cartulaire d'Ouges (XVIIIe siècle, 2e moitié), Archives départementales de la Côte-d'Or, Cart. 196 (11 H 938), Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Abbaye de Cîteaux, 'Transcrits des titres de la layette marquée QQ, 1er cartable, liasses 1, 2 et 3' / Cartulaire d'Ouges (XVIIIe siècle, 2e moitié), Archives départementales de la Côte-d'Or, Cart. 196 (11 H 938), f. 0074, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Applications of cell- and tissue-specific 'omics to improve plant productivity
Creators: name: Hurgobin, Bhavna
name: Lewsey, Mathew
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 310599
subject: Genetics not elsewhere classified
classificationCode: 310899
subject: Plant biology not elsewhere classified

description: The individual tissues and cell types of plants each have characteristic properties that contribute to the function of the plant as a whole. These are reflected by unique patterns of gene expression, protein and metabolite content, which enable cell-type-specific patterns of growth, development and physiology. Gene regulatory networks act within the cell types to govern the production and activity of these components. For the broader organism to grow and reproduce successfully, cell-type-specific activity must also function within the context of surrounding cell types, which is achieved by coordination of signalling pathways. We can investigate how gene regulatory networks are constructed and function using integrative 'omics technologies. Historically such experiments in plant biological research have been performed at the bulk tissue level, to organ resolution at best. In this review, we describe recent advances in cell- and tissue-specific 'omics technologies that allow investigation at much improved resolution. We discuss the advantages of these approaches for fundamental and translational plant biology, illustrated through the examples of specialised metabolism in medicinal plants and seed germination. We also discuss the challenges that must be overcome for such approaches to be adopted widely by the community.
NaHSO4–SiO2-catalyzed aza-Diels–Alder reaction of o-hydroxybenzaldimines with 2,3-dihydrofuran: Diastereoselective synthesis of furanobenzopyrans
Creators: name: Pfanelo Mulokwe
name: Mokgethwa B. Marakalala
name: Mabasa, Tommy F.
name: Henok H. Kinfe
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: NaHSO4 supported on silica gel catalyzes the aza-Diels–Alder reaction of o-hydroxybenzaldimines with 2,3-dihydrofuran to provide furanobenzopyrans in reasonable yields and diastereoselectivity. The catalyst is recyclable and reusable up to two times without a significant loss of activity.
On the Extraction of HCl and H2PtCl6 by Tributyl Phosphate: A Mode of Action Study
Creators: name: Kirstian J. MacRuary
name: Gordon, Ross J.
name: Grant, Richard A.
name: Woollam, Stephen
name: Ellis, Ross J.
name: Tasker, Peter A.
name: Love, Jason B.
name: Morrison, Carole A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Computational Biology

description: Combining computational modeling with experimental measurements has revealed the self-assembly of nano-aggregate structures in the transfer of HCl and PtCl62– from an aqueous phase into toluene by the common industrial extractant tributyl phosphate (TBP). Molecular dynamics simulations have been coupled to analytical measurements to provide an atomistic interpretation of the mode of action of TBP under 6 M and 10 M HCl conditions. The structures conform to reverse micelles, where the Cl– or PtCl62– core is encapsulated by a hydration shell that acts as a mediating bridge to the electronegative oxygen atom in the TBP phosphate groups. For the 6 M HCl extraction model, the data support stable aggregates forming from 2–3 TBP molecules around one chloride anion if the number of water molecules encapsulating the chloride anion is no more than five; increasing the water content to 10 molecules allows a fourth TBP molecule to coordinate. For the 10 M HCl extraction model, stable structures are obtained that conform to the empirical formula (TBP.HCl.H2O)3–5. At 6 M HCl, extraction of PtCl62– is achieved by encapsulation by four TBP molecules; the data for extraction at 10 M HCl indicate larger aggregates containing multiple PtCl62– anions are likely to be forming. In all cases, the hydrated core regions of the reverse micelles are considerably exposed. The diameters of the self-assembled structures around chloride ions agree well with available literature data from small-angle neutron-scattering experiments.
Amtliche Mitteilungen der Technischen Universität Dortmund Nr.16/2020
Creators: name: (:Unkn) Unknown
Publisher: name: Technische Universität Dortmund
Year: 2020
Subjects: subject: 080

description: Fächerspezifische Bestimmungen für das Unterrichtsfach Sozialwissenschaften für ein Lehramt an Gymnasien und Gesamtschulen zur Prüfungsordnung für die Lehramtsmasterstudiengänge an der Technischen Universität Dortmund vom 27. Juli 2020
description: Fächerspezifische Bestimmungen für das Unterrichtsfach Sozialwissenschaften für ein Lehramt an Haupt-, Real-, Sekundar- und Gesamtschulen zur Prüfungsordnung für die Lehramtsmasterstudiengänge an der Technischen Universität Dortmund vom 27. Juli 2020
description: Fächerspezifische Bestimmungen für den Lernbereich Natur- und Gesellschaftswissenschaften (Sachunterricht) für ein Lehramt an Grundschulen zur Prüfungsordnung für die Lehramtsmasterstudiengänge an der Technischen Universität Dortmund vom 27. Juli 2020
description: Fächerspezifische Bestimmungen für den Lernbereich Natur- und Gesellschaftswissenschaften (Sachunterricht) für ein Lehramt für sonderpädagogische Förderung zur Prüfungsordnung für die Lehramtsmasterstudiengänge an der Technischen Universität Dortmund vom 27. Juli 2020
description: Prüfungsordnung für den Bachelorstudiengang Statistik der Fakultät Statistik an der Technischen Universität Dortmund vom 27. Juli 2020
description: Prüfungsordnung für den Masterstudiengang Statistik der Fakultät Statistik an der Technischen Universität Dortmund vom 27. Juli 2020
description: Amtliche Mitteilungen der Technischen Universität Dortmund;2020,16
Amtliche Mitteilungen der Technischen Universität Dortmund Nr.15/2020
Creators: name: (:Unkn) Unknown
Publisher: name: Technische Universität Dortmund
Year: 2020
Subjects: subject: 080

description: Prüfungsordnung für den Bachelorstudiengang Wirtschaftswissenschaften der Fakultät Wirtschaftswissenschaften an der Technischen Universität Dortmund vom 22. Juli 2020
description: Prüfungsordnung für den Masterstudiengang Wirtschaftswissenschaften der Fakultät Wirtschaftswissenschaften an der Technischen Universität Dortmund vom 22. Juli 2020
description: Gemeinsame Prüfungsordnung für den gemeinsamen Masterstudiengang Econometrics der Fakultät für Wirtschaftswissenschaft der Ruhr-Universität Bochum, der Fakultät Statistik unter Beteiligung der Fakultät für Wirtschaftswissenschaften an der Technischen Universität Dortmund sowie der Fakultät für Wirtschaftswissenschaften der Universität Duisburg-Essen vom 31. Juli 2020
description: Amtliche Mitteilungen der Technischen Universität Dortmund;2020,15
Solvent-free nitration of electron-rich arenes
Creators: name: Bhumasamudram Jagadish
name: Hurley, Nathaniel R.
name: Mash, Eugene A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Nitration of relatively electron-rich arenes does not require an additive or a solvent. For example, reaction on a gram scale of anisole with acetyl nitrate, generated in situ by mixing 100% HNO3 with acetic anhydride, produced 2,4-dinitroanisole in 82% yield after crystallization of the crude product. Results with five additional monosubstituted benzene derivatives possessing highly activated, weakly activated, or weakly deactivated rings are reported.
title: ADCO, Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Cart. 198-01 (11 H 1055), 185 folios, f. 0297
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0297, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0297, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Investigation of binding properties of two ethidium derivatives with serum albumins: spectral and computational approach
Creators: name: Akbay, Nuriye
name: Tugba Taskin Tok
name: Seferoğlu, Zeynel
name: Gökoğlu, Elmas
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology

description: The interaction mechanisms of two ethidium derivatives, 3,8-dibenzoylamino-5-ethyl-6-phenylphenantridinium chloride (E2) and 3,8-diphenylacetylamino-5-ethyl-6-phenylphenantridinium chloride (E3) with serum albumins (BSA and HSA) have been investigated by a combined experimental and computational approach. Fluorescence quenching and UV–vis results revealed that the interaction of derivatives with albumins resulted in formation of ground-state complexes and the obtained Stern–Volmer quenching constants designate the presence of a static component in the quenching mechanisms. Thermodynamic parameters (ΔH and ΔS values) point out the ionic interactions play the major role in E2-BSA, E2-HSA and E3-HSA complexes. The van der Waals interactions are dominant forces in E3-BSA complex. Moreover, the obtained results in this study were supported with computational analyzes which have same tendency.
Guidelines to prioritise country contextual factors in policymaking processes
Creators: name: Michas, Serafeim
name: Spyridaki, Niki-Artemis
name: Flamos, Alexandros
name: Williges, Keith
name: Tuerk, Andreas
name: Bößner, Stefan
name: Fujiwara, Noriko
Publisher: name: Zenodo
Year: 2022
Subjects: Climate Change
Decision Making
Policymakers
European Union
Energy Efficiency
Decarbonisation

description: Climate change mitigation efforts have been underway in the EU for many years. EU Member States (MS) have acknowledged the need to reduce greenhouse gas (GHG) emissions and have developed strategic national plans aimed at achieving the environmental goals set by the EU, and by the worldwide community through the United Nations Framework Convention on Climate Change (UNFCCC). It is widely acknowledged that the energy sector is responsible for a major proportion of the total GHG emissions, and the EU is focusing on actions to decarbonise it, including the promotion of renewable energy and energy efficiency upgrades. However, despite careful planning, using best available knowledge, energy and climate policy makers often face situations in which actual policy outcomes differ from policy expectations. Such deviations can occur due to unexpected impacts of the social, economic or political context on the deployment of mitigation technologies and relevant policy outcomes. Throughout this report the focus is set on the factors that broadly hinder the deployment of energy and climate mitigation policies and technologies, and on suggestions for policy makers on how these can be overcome. More specifically, to provide more concrete suggestions and guidelines for national and EU policy makers and to make the scope more operational, accounting also for the aforementioned inherent limitations, the main research question was narrowed down to the following complementary inquiries: What are the most inhibiting contextual factors reported for selected case-studies? How did their influence manifest? How has the country under assessment dealt with identified influences thus far (policy actions, practices considered)? Can examples of different countries which addressed similar influences be of aid? The aim is to synthesise the influence of contextual factors hindering mitigation policy and technology options across different MS contexts and to derive (more) concrete suggestions for policy makers on how to deal with the contextual factors identified.
description: The authors would like to acknowledge the support from the EC. The content of this report is the sole responsibility of its authors and does not necessary reflect the views of the EC.
All-atom molecular dynamics comparison of disease-associated zinc fingers
Creators: name: Godwin, Ryan C.
name: Gmeiner, William H.
name: Salsbury, Freddie R.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: An important regulatory domain of NF-B Essential Modulator (NEMO) is a ubiquitin-binding zinc finger, with a tetrahedral CYS3HIS1 zinc-coordinating binding site. Two variations of NEMO’s zinc finger are implicated in various disease states including ectodermal dysplasia and adult-onset glaucoma. To discern structural and dynamical differences between these disease states, we present results of 48-s of molecular dynamics simulations for three zinc finger systems each in two states, with and without zinc-bound and correspondingly appropriate cysteine thiol/thiolate configurations. The wild-type protein, often studied for its role in cancer, maintains the most rigid and conformationally stable zinc-bound configuration compared with the diseased counterparts. The glaucoma-related protein has persistent loss of secondary structure except within the dominant conformation. Conformational overlap between wild-type and glaucoma isoforms indicate a competitive binding mechanism may be substantial in the malfunctioning configuration, while the alpha-helical disruption of the ectodermal dysplasia suggests a loss of binding selectivity is responsible for aberrant function.
title: ADCO, Boursier de Cîteaux : comptes (1489-1493) (11 H 1166), f. 00262
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Petot, Frédéric
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Boursier de Cîteaux : comptes (1489-1493), Archives départementales de la Côte-d'Or, (11 H 1166). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Boursier de Cîteaux : comptes (1489-1493), Archives départementales de la Côte-d'Or, (11 H 1166), f. 00262, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Landscapes of the Lake Eyre Basin: the catchment-scale context that creates fluvial diversity
Creators: name: Wakelin-King, Gresley
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 370901
subject: Geomorphology and earth surface processes

description: Lake Eyre Basin (LEB) rivers are important but under-researched. This study integrates published and new information into a systematic geomorphological overview, subdividing the LEB into nine landscape zones: basin-margin Uplands with relatively high-energy rivers; Rocky Fringe, piedmont with short rivers and floodouts; Western Rivers, notable for neotectonism and stream capture; low-relief Northern Plains drainages and floodouts; Central Plains dunefield; Channel Country-Vertic Downs, cracking-clay interfluves and valley macrochannels; Channel Country-Stony Domes, rocky or sandy interfluves and complex macrochannels; Lakes & Dunes maintained by saline groundwater; and playas in the Mega-lakes. Zone boundary GIS datasets are available. LEB rivers are shown to be diverse and distinctive, indicating a need for locally relevant knowledge in management and monitoring. Fluvial landform suites include sand-bed rivers, macrochannels hosting coexisting anabranching and anastomosing systems in vertic floodplains, floodouts, low-angle alluvial fans, and three types of waterhole. Channels may be discontinuous or not present; floodplains can dominate flow transmission. Contributing hillslopes are heterogenous in their capacity to generate runoff, while drainage networks may have low to high degrees of integration. Management implications include the importance of in-river terrestrial ecosystems and “patchy” drainage networks, and the inapplicability of some morphometric practices.
NaHSO4–SiO2 catalysed aza-Diels-Alder reaction of o-hydroxybenzaldimines with 2,3-dihydrofuran: Diastereoselective synthesis of furanobenzopyrans
Creators: name: Pfanelo Mulokwe
name: Mokgethwa B. Marakalala
name: Mabasa, Tommy F.
name: Henok H. Kinfe
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: NaHSO4 supported on silica gel catalyses the aza-Diels-Alder reaction of o-hydroxybenzaldimines with 2,3-dihydrofuran to provide furanobenzopyrans in reasonable yields and diastereoselectivity. The catalyst is recyclable and reusable up to two times without a significant loss of activity.
Methodi correctae et auctae iconibusque illustratae Testacea marina in suas debitas classes, genera et species distribuendi secundum suas notas characteristicas, pars tertia: Cochleae marinae breviores et magis contractae, id est Cochleae marinae ore et turbine parum, aut nihil elongatis
Creators: name: Unkown
Publisher: name: Zenodo
Year: 1738

description: Lateinisch Schenkung des Naturhistorischen Museums Luzern an die Kantonsbibliothek Luzern 1916 Verzeichnung=Description=Inventaire 27.03.1995 HAN-Katalogisierungsregeln pk Digitalisierung=Digitization=Numérisation TIFF 05.04.2015
title: Listening to and Incorporating the Voices of Sessional Academic Staff: Building a Supportive and Sustainable Workplace for Women at Western Sydney University. Final Research Report to Vice Chancellor's Gender Equity Fund
Creators: name: Kanitkar, Ashwini
name: Laurance, Nicky
name: Mears, Jane
Publisher: name: Western Sydney University
Year: 2020

description: This is the final report for the project ‘Listening to and Incorporating the Voices of Sessional Academic Staff: Building a Supportive and Sustainable Workplace for Women at Western Sydney University’. The aim of this project was to document the experiences of female sessional staff, to explore strategies adopted by those sessional staff members to improve their working and personal lives, to make recommendations for change and ultimately, to build a supportive and sustainable workplace for women at Western Sydney University (WSU).  We report here on our findings from data collected in confidence, by sessional staff. We planned the research, designed the survey and interview questions, distributed the survey, conducted interviews and analysed data. The research team was comprised entirely of sessional staff.
We created a safe and supportive space where participants could share their experiences at interview, without fear of repercussions. We provided our colleagues with the opportunity to tell us about their experiences through an anonymous survey. We also held formal consultations, webinars and focus groups, and spoke informally with sessional staff.
The goals of this research were to draw on and privilege the experience, knowledge and leadership of female casual academics at WSU,  provide a culturally safe, supportive and gender inclusive environment for women employed as casuals to share experiences and strategies and interview and bring together 10–15 women (former or current casual academic staff) to share positive and negative experiences discuss, analyse and document supportive policies and practices, both informal and formal, and to recommend ways to build a welcoming, supportive and sustainable workplace for all women at WSU.
title: ADCO, Cartulaire de Saint-Etienne de Dijon (XIIIe siècle), Cart. 34 (G 138), 22 folios, f. 0030
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire de Saint-Etienne de Dijon (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 34 (G 138), 22 folios, f. 0030, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Saint-Etienne de Dijon (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 34 (G 138), 22 folios, f. 0030, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
title: Gravity Anomalies Along the East Scotia Ridge: Constraining the Relative Importance of Magmatic and Tectonic Controls on Crustal Accretion
Creators: name: Nicholson, Briton Lee
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 2012

description: Similar to regions such as the Lau Basin and the Caribbean Sea, the eastern Scotia Sea is a geologically complex area that involves multiple plate boundary types. This study uses bathymetry and gravity data to infer upper mantle geodynamics in the eastern Scotia Sea region. Beneath this region is an intermediate-rate back-arc spreading center known as the East Scotia Ridge (ESR) that forms the boundary between the Scotia and Sandwich plates. To the east of the ESR are the South Sandwich island arc and the South Sandwich Trench. The ESR is a relatively young feature, with spreading estimated to have begun ~20 Ma (Livermore, 2003).

Earlier studies examining trends in bathymetry and geochemistry along the north-south striking ESR ( e.g., Livermore, 2003) suggested that westward-directed flow from the Bouvet plume, located approximately 2000 km to the east, may affect ridge magmatic processes at segments near the slab ends, particularly in the north. In this investigation mantle Bouguer anomaly (MBA) is calculated for the eastern Scotia Sea to evaluate the relative importance of magmatic and tectonic factors in controlling crustal accretion along the ESR.

MBA values do not indicate the presence of enhanced, plume-dominated upwelling beneath the northernmost and southernmost segments. Likewise, geochemical data from published sources do not show a clear thermal plume influence. Overall, a mechanism of geochemical source heterogeneity plus enhanced melting due to plate boundary geometry, rather than a "classic" thermal plume, is preferred to explain geophysical anomalies along the ESR.
Theory Of Universal Origins.pdf
Creators: name: Matshaba, Romeo D.
Publisher: name: figshare
Year: 2017
Subjects: Cosmology
General Relativity
Quantum Mechanics

description: About a century ago, Albert Einstein realized how the Theory of Newton's Universal Gravitation was inadequate to describe nature and needed to be revised in order to be neatly incorporated into the relativistic scheme with its undesirable instantaneous force shortcomings. Since then we have come to adopt the relativistic high energy tensor theory of General Relativity, which saw its inception into mainstream physics in the year 1916. General Relativity has stood firm against varied tests, such as: gravitational lensing, perihelion of mercury, gravitational time dilation, PSR1913+16 etc, but with the steady advancement of Quantum Mechanics, and its overwhelming experimental success, we are yet again faced with the same problem that was faced a century ago, but this time, the problem is much worse, and the elephant in the room is General Relativity. The fact that General relativity and Quantum mechanics, share different views in the description of space and time or space-time, with quantum mechanics in favor of the latter and general relativity of the former; does not allow one to have a smooth transition from one representation to the other. This automatically implies that for scenarios where both quantum mechanics and gravity / general relativity are required, then that scenario is unsolvable with our current model of physics (hence either General Relativity or Quantum Mechanics is flawed). It becomes clear from the microscopic realm of quantum mechanics and the cosmological problems associated with General Relativity, such as dark energy, dark matter, the inflation force... perhaps a bit closer to home for general relativity being the singularities inherent in its own equations, and the very nature of General Relativity, allowing mostly approximate solutions (reason why most physicist, even today still cling to Newtonian dynamics), because of this and more a new theory of gravity is required – the much anticipated “Quantum Gravity” – just as it was required those many years ago. In the theory that I propose, we will see how from the most basic concepts of quantum mechanics, a theory of gravity can emerge that has the power to not only be mathematically simpler than General Relativity, explain dark energy, dark matter and inflation without any ad-hoc mechanisms, but also have the power to unify all the forces of nature into a single unified theory of everything.
CHILDREN WITH DISABILITY OR LEARNING DIFFICULTIES A COMPARISON BETWEEN AN INSTITUTE WITH A MULTI-DISCIPLINARY TEAM AND AN INSTITUTE WITH A SINGLE SPECIAL EDUCATOR
Creators: name: Mathur, Anshu
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390307
subject: Teacher education and professional development of educators
classificationCode: 390407
subject: Inclusive education
classificationCode: 390411
subject: Special education and disability

description: Case based study
Materials (in English)
Creators: name: Strohmaier, Niek
name: Struchiner, Noel
name: Hannikainen, Ivar Rodríguez
name: Dranseika, Vilius
name: Poama, Andrei
name: Tobia, Kevin
name: Kneer, Markus
name: Bystranowski, Piotr
name: Rosas, Alejandro
name: Sommers, Roseanna
name: Da Franca Couto Fernandes De Almeida, Guilherme
Publisher: name: OSF Registries
Year: 2018

description: This is where you can upload stimuli/materials whenever they're ready for distribution.
Supporting Information from Effects of motion in structured populations
Creators: name: Krieger, Madison S.
name: McAvoy, Alex
name: Nowak, Martin A.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences

description: In evolutionary processes, population structure has a substantial effect on natural selection. Here, we analyse how motion of individuals affects constant selection in structured populations. Motion is relevant because it leads to changes in the distribution of types as mutations march towards fixation or extinction. We describe motion as the swapping of individuals on graphs, and more generally as the shuffling of individuals between reproductive updates. Beginning with a one-dimensional graph, the cycle, we prove that motion suppresses natural selection for death–birth (DB) updating or for any process that combines birth–death (BD) and DB updating. If the rule is purely BD updating, no change in fixation probability appears in the presence of motion. We further investigate how motion affects evolution on the square lattice and weighted graphs. In the case of weighted graphs, we find that motion can be either an amplifier or a suppressor of natural selection. In some cases, whether it is one or the other can be a function of the relative reproductive rate, indicating that motion is a subtle and complex attribute of evolving populations. As a first step towards understanding less restricted types of motion in evolutionary graph theory, we consider a similar rule on dynamic graphs induced by a spatial flow and find qualitatively similar results indicating that continuous motion also suppresses natural selection.
Paracrine IL-6 Signaling Confers Proliferation between Heterogeneous Inflammatory Breast Cancer Sub-Clones
Creators: name: Morrow, Riley
name: Allam, Amr
name: Yeo, B
name: Deb, S
name: Murone, C
name: Lim, E
name: Johnstone, Cameron
name: Ernst, Matthias
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 321199
subject: Oncology and carcinogenesis not elsewhere classified

description: Inflammatory breast cancer (IBC) describes a highly aggressive form of breast cancer of diverse molecular subtypes and clonal heterogeneity across individual tumors. Accordingly, IBC is recognized by its clinical signs of inflammation, associated with expression of interleukin (IL)-6 and other inflammatory cytokines. Here, we investigate whether sub-clonal differences between expression of components of the IL-6 signaling cascade reveal a novel role for IL-6 to mediate a proliferative response in trans using two prototypical IBC cell lines. We find that SUM149 and SUM 190 cells faithfully replicate differential expression observed in a subset of human IBC specimens between IL-6, the activated form of the key downstream transcription factor STAT3, and of the HER2 receptor. Surprisingly, the high level of IL-6 produced by SUM149 cells activates STAT3 and stimulates proliferation in SUM190 cells, but not in SUM149 cells with low IL-6R expression. Importantly, SUM149 conditioned medium or co-culture with SUM149 cells induced growth of SUM190 cells, and this effect was abrogated by the IL-6R neutralizing antibody Tocilizumab. The results suggest a novel function for inter-clonal IL-6 signaling in IBC, whereby IL-6 promotes in trans proliferation of IL-6R and HER2-expressing responsive sub-clones and, therefore, may provide a vulnerability that can be exploited therapeutically by repurposing of a clinically approved antibody.
Measuring border effects in European cross-border regions
Creators: name: Capello, Roberta
name: Caragliu, Andrea
name: Fratesi, Ugo
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: This paper presents a new methodology to measure border effects from a different perspective with respect to the standard gravitational approach. The methodology proposed measures supply-side border effects by identifying two types of limits produced by the border to the productive system: inefficiency in exploiting local resources (efficiency needs) and scarce endowment of resources (endowment needs), the former calling for intervention on resource governance, the latter requiring new investment. The methodology, applied to the European Union’s Cross Border Cooperation Program regions, suggests a stronger presence of efficiency needs with respect to endowment ones.
Removals of estrone and 17β-estradiol by microalgae cultivation: kinetics and removal mechanisms
Creators: name: Chantima Ruksrithong
name: Songkeart Phattarapattamawong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology
subject: Plant Biology

description: Occurrence of estrone (E1) and 17β-estradiol (E2) in the environment has attracted the public attention since E1 and E2 cause estrogenicity in aquatic microorganisms. Microalgae cultivation in wastewater is considered as an economical practice since microalgae can be used for not only pollutant removals, but also as energy resources. This research aims to investigate the removals of E1 and E2 in synthetic wastewater by microalgae (i.e. Chlorella vulgaris and Scenedesmus obliquus). At the steady state, S. obliquus removed E1 and E2 by 91% and 99%, respectively. C. vulgaris removed E1 and E2 by 52% and 99%, respectively. Interestingly, the occurrence of E1 was observed when E2 was degraded by microalgae. The predominant mechanism for E1 and E2 removals was biodegradation, followed by adsorption. The adsorption kinetic and isotherm for both E1 and E2 can be described by the pseudo-second-order and Freundlich model. The addition of E1 and E2 resulted in a higher lipid content of microalgae by 1–9%.
Influence of habitat modification by livestock on páramo bird abundance in southern Andes of Ecuador
Creators: name: Astudillo, Pedro X.
name: Barros, Santiago
name: Siddons, David C.
name: Zárate, Edwin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Livestock grazing on natural grasslands is widespread with negative consequences to biodiversity. In the High Andes, páramo grassland is a distinctive ecosystem where the influence of livestock grazing on páramo birds is poorly documented. We assessed the influence of habitat modification of páramo grassland related to livestock grazing on bird habitat guilds in the southern Andes of Ecuador. We recorded birds occurring along transects located in areas which showed a gradient (low to high) of grazing pressure. We found a decrease in abundance of páramo specialists in transects with more grazing pressure. We interpret this habitat modification as loss of key habitat necessary for habitat-specialized birds.