cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Spatial metallicity asymmetry in $ω$ Centauri
Creators: name: Jurcsik, Johanna
name: Observatory, Konkoly
name: Budapest
name: Hungary
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The compilation of the metallicity values of $ω$~Centauri stars led to detection of spatial asymmetry in the metallicity distribution of the bright giants. It was found that the most and least metal-poor objects are separated along galactic latitude. Statistical tests show that the chance occurrence of the phenomenon is very low. The subgiant and the RR~Lyrae samples do not show, however, similar segregation of the different metallicity objects. The physical parameters of the variables calculated by using empirical formulae indicate that the bulk of the RRab stars comprises a very homogeneous group regarding both their metallicity and mass values. These stars are most probably already in the evolved stage of their horizontal branch evolution.
description: 9 pages, 4 Postscript figures, accepted for publication in ApJ Letters
Multi-Level Spectral Deferred Corrections Scheme for the Shallow Water Equations on the Rotating Sphere
Creators: name: Hamon, Francois
name: Schreiber, Martin
name: Minion, Michael
Publisher: name: arXiv
Year: 2018
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Efficient time integration schemes are necessary to capture the complex processes involved in atmospheric flows over long periods of time. In this work, we propose a high-order, implicit-explicit numerical scheme that combines Multi-Level Spectral Deferred Corrections (MLSDC) and the Spherical Harmonics (SH) transform to solve the wave-propagation problems arising from the shallow-water equations on the rotating sphere. The iterative temporal integration is based on a sequence of corrections distributed on coupled space-time levels to perform a significant portion of the calculations on a coarse representation of the problem and hence to reduce the time-to-solution while preserving accuracy. In our scheme, referred to as MLSDC-SH, the spatial discretization plays a key role in the efficiency of MLSDC, since the SH basis allows for consistent transfer functions between space-time levels that preserve important physical properties of the solution. We study the performance of the MLSDC-SH scheme with shallow-water test cases commonly used in numerical atmospheric modeling. We use this suite of test cases, which gradually adds more complexity to the nonlinear system of governing partial differential equations, to perform a detailed analysis of the convergence rate of MLSDC-SH upon refinement in time. We illustrate the good stability properties of MLSDC-SH and show that the proposed scheme achieves up to eighth-order accuracy in time. Finally, we study the conditions in which MLSDC-SH achieves its theoretical speedup, and we show that it can significantly reduce the computational cost compared to single-level Spectral Deferred Corrections (SDC).
Capra mambrica Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Artiodactyla
Bovidae
Capra
Capra mambrica

description: Capra mambrica [spec. nov.]
C. auribus pendulis longissimis. Syst. nat. 14.
Capra mambrica s. syriaca. Gesn. quadr. 153. Raj. quadr. 81. Alp. aegypt. 229.
Habitat in India.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 70, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Synchronized optical and electrical detection of biomolecules using a low-noise nanopore platform
Creators: name: Pitchford, William
Publisher: name: Imperial College London
Year: 2015

description: Nanopore biosensors are a relatively new tool for single-molecule detection, whose inception was inspired by molecular transport through transmembrane pores in nature and the operating principle of the Coulter Counter, so-called resistive pulse sensing. In recent years, nanopores have been integrated with alternative detection modes, such as fluorescence spectroscopy, with the goal of increasing structural resolution and analytical throughput. The integration of fluorescence spectroscopy is particularly useful as fluorescent labels can be used to identify different regions of a molecule; discriminate molecules in heterogeneous solutions and probe molecular properties such as distance. This thesis describes the development and application of a unique low-noise nanopore platform, composed of a predominately pyrex substrate and silicon nitride membrane, for synchronized optical and electrical detection of biomolecules. The use of a pyrex substrate was pursued as commonly used Si substrate based nanopore sensors exhibit high ionic current noise with and without laser illumination. This limits their applicability to high-laser-power, high- bandwidth electronic measurements, which in-turn restricts the range of molecules that can be studied and the structural resolution provided by resistive pulse sensing. Proof-of-principle experiments are presented that show a pyrex substrate greatly reduces ionic current noise arising from both platform capacitance and laser illumination. Furthermore, using a confocal microscope and a pyrex based platform with a partially metallic nanopore, thereby acting as a zero mode waveguide, we demonstrate synchronized optical and electrical of dsDNA. The high translocation velocity of biomedically relevant molecules such as proteins and nucleic acids means there is a continual drive for low-noise high-bandwidth measurements within the nanopore community. The use of these low-noise platforms for synchronized measurements increases the sensitivity of resistive pulse sensing and therefore the range of molecules that can be studied and potential applications of the sensor.
Renoprotective Effect of Baicalin Against Titanium Dioxide Nanoparticles Induced Nephrotoxicity in Rats
Creators: name: H.L. Abdulhadi
name: L.H. Ali
name: B.Y. Mehdi
Publisher: name: Opera Medica et Physiologica
Year: 2024
Subjects: renoprotactive
baicalin
TiO2NPs
nephrotoxicity

description: The safety of titanium dioxide nano-particles (TiO2NPs) is currently being questioned. TiO2NPs have multiple uses in disinfectants, plastics, cosmetics, and food coloring. Our goal was to determine if administering Baicalin (50 mg/kg body weight) could help lessen the harmful effects caused by TiO2NPs (100 mg/kg body weight) in rats. By reducing kidney damage from TiO2NPs, treatment with Bai led to lower levels of creatinine (Cr), urea (Ur), and uric acid (UA). The harmful effects of TiO2NPs can be counteracted by Baicalin, which has demonstrated its ability to protect the kidneys. Additionally, it can restore balance between oxidation and antioxidants by increasing CAT, SOD, GSH, and reducing malondialdehyde levels. Not only does it exhibit anti-inflammatory effects by downregulating IL-6 and TNFand increasing IL-10, but it also contributes to maintaining equilibrium in the body.
In vivo assessment of class-specific inducible inhibitors of metalloproteinases in osteoarthritis
Creators: name: Lo Cascio, Leandro
Publisher: name: Imperial College London
Year: 2015

description: The role of articular cartilage is providing a painless and attrition-free surface for joints movements. Osteoarthritis (OA) is a debilitating multifactorial pathology characterized by progressive articular cartilage loss, exposition of the bone surface accompanied by pain, and final loss of joint functions. To date there is not an effective alternative to surgical replacement of damaged joints. Metalloproteinases (MPs) play an important role in cartilage remodelling both in physiological and pathological conditions. Among the metalloproteinases, the aggrecanase family was shown to be the major family responsible for aggrecan breakdown, while matrix metalloproteinases (MMPs) target preferentially the collagen molecules. Tissue inhibitor of metalloproteinases (TIMPs) are the endogenous regulators of those enzymes and in particular TIMP-3 was found to possess the broadest activity. So far all synthetic MP inhibitors failed in trials for OA treatment, and TIMP-3 may prove to be a possible alternative. Notably several synthetic mutants were generated to restrict its activity towards metalloproteinases. In order to test the potential therapeutic effects of these proteins, I decided to employ transgenic overexpressing mice. However I appreciated that it is of paramount importance to restrict the exogenous expression just to cartilage. Moreover because it was previously observed that overexpression of TIMP-3 in cartilage severely affects bone development and caused embryonic lethality, I decided to generate tissue specific inducible transgenic mice. I focused on the Aggrecan promoter in order to achieve specific cartilage expression and the Cre/loxP system to obtain inducible expression. Here I show the design and generation of a new aggrecan-driven Cre deleter mouse line. These mice can effectively target floxed genes in cartilage. I also show the generation of inducible TIMP-expressing mouse lines for both a cartilage-specific and ubiquitous expression. I aim to induce OA in those transgenic mice, after induction of TIMPs expression, to evaluate the inhibitors role in OA treatment.
SIMPs through the axion portal
Creators: name: Hochberg, Yonit
name: Kuflik, Eric
name: McGehee, Robert
name: Murayama, Hitoshi
name: Schutz, Katelin
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Dark matter could be a thermal relic comprised of strongly interacting massive particles (SIMPs), where $3 \rightarrow 2$ interactions set the relic abundance. Such interactions generically arise in theories of chiral symmetry breaking via the Wess-Zumino-Witten term. In this work, we show that an axion-like particle can successfully maintain kinetic equilibrium between the dark matter and the visible sector, allowing the requisite entropy transfer that is crucial for SIMPs to be a cold dark matter candidate. Constraints on this scenario arise from beam dump and collider experiments, from the cosmic microwave background, and from supernovae. We find a viable parameter space when the axion-like particle is close in mass to the SIMP dark matter, with strong-scale masses of order a few hundred MeV. Many planned experiments are set to probe the parameter space in the near future.
description: 8+6 pages, 2 figures. v2: published in PRD with minor revisions (no change to results)
The role of refractive index in metalens performance
Creators: name: Bayati, Elyas
name: Zhan, Alan
name: Colburn, Shane
name: Majumdar, Arka
Publisher: name: arXiv
Year: 2018
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Sub-wavelength diffractive optics, commonly known as metasurfaces, have recently garnered significant attention for their ability to create ultra-thin flat lenses with extremely short focal lengths. Several materials with different refractive indices have been used to create metasurface lenses (metalenses). In this paper, we analyze the role of material refractive indices on the performance of these metalenses. We employ both forward and inverse design methodologies to perform our analysis. We found that, while high refractive index materials allow for extreme reduction of the focal length, for moderate focal lengths and numerical aperture (<0.6), there is no appreciable difference in focal spot-size and focusing efficiency for metalenses made of different materials with refractive indices ranging between n= 1.25 to n=3.5.
The Kinematics of the Ionized and Molecular Hydrogen in the Starburst Galaxy NGC 253
Creators: name: Prada, F.
name: Manchado, A.
name: Canzian, B.
name: Peletier, R. F.
name: McKeith, C. D.
name: Beckman, J. E.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Near-infrared H_2 1-0 S(1) and Br_gamma velocity curves along the major axis of NGC 253 have revealed a central velocity gradient that is seven times steeper than that shown by the optical velocity curve. This is interpreted as an optical depth effect due to dust. Approximately 35 mag of visual extinction in the center is required to match the SW side of the optical velocity curve. The spatial variation of the ratio of these lines to the CO (J=1-0) line is compared among starburst galaxies NGC 253, M82, and NGC 4945 to investigate the excitation mechanism responsible for the H_2 1-0 S(1) line.
description: Uuencoded postscript file, 10 pages (4 tables included), 8 figures available on request to fprada@ibm-3.mpa-garching.mpg.de, Ap.J. (in press)
Subconjunctival Use of Mesenchymal Stem Cells for the Treatment of Canine Ulcerative Keratitis
Creators: name: A.N. Valeeva
name: A.G. Malanyeva
name: C.S. Rutland
name: A.M. Aimaletdinov
name: E.Y. Zakirova
Publisher: name: Opera Medica et Physiologica
Year: 2024
Subjects: ophthalmic diseases
ulcerative keratitis
allogeneic mesenchymal stem cells
MSC transplantation
subconjunctival injections
cell therapy

description: Ophthalmic diseases are common problems in dogs of various breeds and ages. In recent years, ophthalmol-ogists have been paying more attention to stem cell (SC) therapies, since the renewal and regeneration of any tissue in the adult body depends on somatic SC, and eye tissues are no exception. The aim of the present work was to determine the influence of allogenic mesenchymal stem cells (MSC) in healing ulcerative keratitis of dogs. Our research showed that subconjunctival injections of allogeneic MSCs from adipose tissue was clinically safe for use in dogs during the follow-up period. These injections contributed to the decrease of the clinical manifestations of ulcerative keratitis in dogs, as evidenced by a decrease the intensity and area of the affected areas of the cornea compared to classic therapy.
CO Distribution and Kinematics Along the Bar in the Strongly Barred Spiral NGC 7479
Creators: name: Laine, S.
name: Kenney, J. D. P.
name: Yun, M. S.
name: Gottesman, S. T.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report on the 2.5 arcsec (400 pc) resolution CO (J = 1 -> 0) observations covering the whole length of the bar in the strongly barred late-type spiral galaxy NGC 7479. CO emission is detected only along a dust lane that traverses the whole length of the bar, including the nucleus. The emission is strongest in the nucleus. The distribution of emission is clumpy along the bar outside the nucleus, and consists of gas complexes that are unlikely to be gravitationally bound. The CO kinematics within the bar consist of two separate components. A kinematically distinct circumnuclear disk, < 500 pc in diameter, is undergoing predominantly circular motion with a maximum rotational velocity of 245 km/s at a radius of 1 arcsec (160 pc). The CO-emitting gas in the bar outside the circumnuclear disk has substantial noncircular motions which are consistent with a large radial velocity component, directed inwards. The CO emission has a large velocity gradient across the bar dust lane, ranging from 0.5 to 1.9 km/s/pc after correcting for inclination, and the projected velocity change across the dust lane is as high as 200 km/s. This sharp velocity gradient is consistent with a shock front at the location of the bar dust lane. A comparison of H-alpha and CO kinematics across the dust lane shows that although the H-alpha emission is often observed both upstream and downstream from the dust lane, the CO emission is observed only where the velocity gradient is large. We also compare the observations with hydrodynamic models and discuss star formation along the bar.
description: 16 pages, including 10 figures. Accepted for publication in ApJ
The Influence of Genes, miRNAs and Retroelements on Psychological Well-Being
Creators: name: R.N. Mustafin
name: E.K. Khusnutdinova
Publisher: name: Opera Medica et Physiologica
Year: 2024
Subjects: genes
depression
long non-coding RNAs
microRNAs
heritability
psychological well-being
transposons

description: The heritability of human psychological well-being ranges from 36 to 48%. GWAS conducted between 2016 and 2019 identified 364 SNPs significant for well-being. A significant association with psychological well-being has been shown for the APOE, OXTR, OXT, NMUR2, CNR1, CRHR1, and CYP19A1 genes. The greatest influence on psychological well-being is exerted by allelic variants of the MAYA, 5-HTT, СOMT genes, and the CTRA gene group (conservative transcriptional response to adversity). Brain functioning is influenced by the peculiarities of VNTR distribution in the regulatory regions of the 5-HTT, SLC6A3, AVPR1A, FUS, OXT, PARK7, POMC, TACR3, TRPV1 and TRPV3 genes. These features are due to the individual distribution of SVA (SINE-VNTR-Alu) retroelements, which belong to transposons that are drivers of epigenetic regulation. Features of activation of retroelements located in the regulatory regions of genes may affect the individual level of well-being. This is evidenced by the association with psychological well-being of DRD4, MAOA, SLC6A3, 5-HTT genes alleles, determined by the length of VNTR in their regulatory regions. Evidence of retroelements role in well-being regulation is that retroelements are sources of proteincoding genes and microRNAs involved in brain functioning. The Arc gene, derived from retroelements, is characterized by transport into neuronal dendrites with translation regulation. We analyzed the MDTE DB database on transposonderived microRNAs and scientific literature. According to the results, 12 miRNAs, derived from transposons, are associated with major depressive disorder. The data obtained indicate the influence of transposons on psychological wellbeing, which is assessed by the absence of depression.
High performance in colorectal surgery
Creators: name: Byrne, Benjamin
Publisher: name: Imperial College London
Year: 2015

description: A large body of international outcomes research has documented significant variation in the results of health care, beyond differences attributable to patient age, comorbidity or chance. Naturally, quality of care, however measured, may vary by provider within a health care system. Yet detailed understanding of the relationship between quality of care and health care outcomes continues to elude researchers. Much research has focused on the patient level, determining which patient-focused clinical processes deliver the best outcomes. By contrast, there is a relative lack of research examining intermediate and higher levels, to understand team performance and how teams work to provide high quality care, though research in this area is growing. This thesis aims to develop a greater understanding of how the best colorectal surgical units may be identified, and how they achieve their results. Chapter 1 provides background to the present approach to the assessment of performance in health care. Chapter 2 summarises salient surgical outcomes research, and chapter 3 presents a literature review of evidence associating specific organisational structures and processes with clinical outcomes. Chapter 4 presents a patient questionnaire study, undertaken to assess the involvement of patients with gastrointestinal cancer in choosing a provider, and what provider-level information patients consider important. Chapters 5 to 8 describe the methods and results of a series of studies using routine administrative data to explore changes within colorectal surgery over time, as well as the relationship between different outcome measures at the unit level. Chapters 9 to 12 present research designed to understand how units achieve their results. This work included developing a semi-structured interview to better understand the key organisational factors determining length of stay after elective colonic surgery. Chapter 13 summarises the main findings and limitations of this thesis, and discusses its implications for practice and future research.
Additional file 2: of A theory-based multi-component intervention to increase reactive balance measurement by physiotherapists in three rehabilitation hospitals: an uncontrolled single group study
Creators: name: Sibley, Kathryn
name: Bentley, Danielle
name: Salbach, Nancy
name: Gardner, Paula
name: McGlynn, Mandy
name: OâHoski, Sachi
name: Shaffer, Jennifer
name: Shing, Paula
name: McEwen, Sara
name: Beauchamp, Marla
name: Hossain, Saima
name: Straus, Sharon
name: Jaglal, Susan
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Meeting agendas. (DOC 32 kb)
Absence of Stress-induced Anisotropy during Brittle Deformation in Antigorite Serpentinite
Creators: name: David, Emmanuel C.
name: Brantut, Nicolas
name: Hansen, Lars N.
name: Mitchell, Thomas M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Knowledge of the seismological signature of serpentinites during deformation is fundamental for interpreting seismic observations in subduction zones, but this has yet to be experimentally constrained. We measured compressional and shear wave velocities during brittle deformation in polycrystalline antigorite, at room temperature and varying confining pressures up to 150 MPa. Ultrasonic velocity measurements, at varying directions to the compression axis, were combined with mechanical measurements of axial and volumetric strain, during direct loading and cyclic loading triaxial deformation tests. An additional deformation experiment was conducted on a specimen of Westerly granite for comparison. At all confining pressures, brittle deformation in antigorite is associated with a spectacular absence of stress-induced anisotropy and with no noticeable dependence of wave velocities on axial compressive stress, prior to rock failure. The strength of antigorite samples is comparable to that of granite, but the mechanical behaviour is elastic up to high stress ($\gtrsim80$\% of rock strength) and non-dilatant. Microcracking is only observed in antigorite specimens taken to failure and not in those loaded even at $90-95$\% of their compressive strength. Microcrack damage is extremely localised near the fault and consists of shear microcracks that form exclusively along the cleavage plane of antigorite crystals. Our observations demonstrate that brittle deformation in antigorite occurs entirely by "mode II" shear microcracking. This is all the more remarkable than the preexisting microcrack population in antigorite is comparable to that in granite. The mechanical behaviour and seismic signature of antigorite brittle deformation thus appears to be unique within crystalline rocks.
description: 22 pages, 17 figures, 2 tables
Previrialization: Perturbative and N-Body Results
Creators: name: Lokas, Ewa L.
name: Juszkiewicz, Roman
name: Bouchet, Francois R.
name: Hivon, Eric
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a series of N-body experiments which confirm the reality of the previrialization effect. We also use weakly nonlinear perturbative approach to study the phenomenon. These two approaches agree when the rms density contrast, $σ$, is small; more surprisingly, they remain in agreement when $σ\approx 1$. When the slope of the initial power spectrum is $n>-1$, nonlinear tidal interactions slow down the growth of density fluctuations and the magnitude of the suppression increases when $n$ (i.e. the relative amount of small scale power) is increased. For $n
description: Significantly revised, 25 pages, uuencoded compressed postscript, figures included, to appear in ApJ
Model checking GSM-based multi-agent systems
Creators: name: Gonzalez, Pavel
Publisher: name: Imperial College London
Year: 2014

description: Business artifacts are a growing topic in service oriented computing. Artifact systems include both data and process descriptions at interface level thereby providing more sophisticated and powerful service inter-operation capabilities. The Guard-Stage-Milestone (GSM) language provides a novel framework for specifying artifact systems that features declarative descriptions of the intended behaviour without requiring an explicit specification of the control flow. While much of the research is focused on the design, deployment and maintenance of GSM programs, the verification of this formalism has received less attention. This thesis aims to contribute to the topic. We put forward a holistic methodology for the practical verification of GSM-based multi-agent systems via model checking. The formal verification faces several challenges: the declarative nature of GSM programs; the mechanisms for data hiding and access control; and the infinite state spaces inherent in the underlying data. We address them in stages. First, we develop a symbolic representation of GSM programs, which makes them amenable to model checking. We then extend GSM to multi-agent systems and map it into a variant of artifact-centric multi-agent systems (AC-MAS), a paradigm based on interpreted systems. This allows us to reason about the knowledge the agents have about the artifact system. Lastly, we investigate predicate abstraction as a key technique to overcome the difficulty of verifying infinite state spaces. We present a technique that lifts 3-valued abstraction to epistemic logic and makes GSM programs amenable to model checking against specifications written in a quantified version of temporal-epistemic logic. The theory serves as a basis for developing a symbolic model checker that implements SMT-based, 3-valued abstraction for GSM-based multi-agent systems. The feasibility of the implementation is demonstrated by verifying GSM programs for concrete applications from the service community.
Costs related to frontotemporal dementia in Latin America: a scoping review of economic health studies
Creators: name: Alva Diaz, Carlos
name: Rodriguez, Aaron
name: Málaga, Marco
name: Morán-Mariños, Cristian
name: VELASQUEZ RIMACHI, VICTOR ANDRÉS
name: Custodio, Nilton
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Economics

description: Scoping protocol review costs to assess costs related to frontotemporal dementia in Latin America.
The Luminous Starburst Ring in NGC 7771: Sequential Star Formation?
Creators: name: Smith, Denise A.
name: Herter, Terry
name: Haynes, Martha P.
name: Neff, Susan G.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Only two of the twenty highly luminous starburst galaxies analyzed by Smith et al. exhibit circumnuclear rings of star formation. These galaxies provide a link between 10^11 L_sun systems and classical, less-luminous ringed systems. We report the discovery of a near-infrared counterpart to the nuclear ring of radio emission in NGC 7771. A displacement between the ~10 radio bright clumps and the ~10 near-infrared bright clumps indicates the presence of multiple generations of star formation. The estimated thermal emission from each radio source is equivalent to that of ~35000 O6 stars. Each near-infrared bright knot contains ~5000 red supergiants, on average. The stellar mass of each knot is estimated to be ~10^7 M_sun. The implied time-averaged star formation rate is \~40 M_sun per yr. Several similarities are found between the properties of this system and other ringed and non-ringed starbursts. Morphological differences between NGC 7771 and the starburst + Seyfert 1 galaxy NGC 7469 suggest that NGC 7771 may not be old enough to fuel an AGN, or may not be capable of fueling an AGN. Alternatively, the differences may be unrelated to the presence or absence of an AGN and may simply reflect the possibility that star formation in rings is episodic.
description: accepted for publication in The Astrophysical Journal (10 January 1999); 48 pages including 13 figures; AAS LaTex
Total and Specific IgE in Sera of Patients Complaining Bronchoconstriction Post-COVID-19 Infection
Creators: name: A.K. Bediwi
name: S.A. Lafi
name: H.I. Ghazzay
Publisher: name: Opera Medica et Physiologica
Year: 2024
Subjects: COVID-19
total IgE
specific IgE
bronchoconstriction.

description: The link between infections and hypersensitivity reactions was revealed by many pioneers. Many researchers found that detectable IgE is specific to bacteria and viruses in sera of infected patients. Some patients undergo a post-COVID-19 bronchospasm due to a reaction to the viral antigens. This study aimed to reveal the association between COVID-19 infection and respiratory allergy in post-COVID-19 convalescent patients. The blood specimens were taken from each of the patients and control individuals. Complete cell blood count (CBC), anti-COVID-19 virus IgM, IgG, as well as IL-5, total IgE and IgE specific for COVID-19 antigen were done for each of patients and control individuals. The results: no significant difference was found in the mean number of the total WBCs, neutrophil and monocyte cells between patients and control individuals. Patients who were suffering from bronchoconstriction and showed high total and specific IgE revealed normal percentage of eosinophil and high basophil. The basophil ratio undergoes an increase in COVID-19 patients who were suffering from bronchoconstriction during and after post-COVID-19 infection. Furthermore, a positive correlation was found between IL-5, total IgE, COVID-19 antigen specific IgE and basophils in patients while a normal relation was found between parameters and control individuals. We can conclude that bronchospasm is one of the post-COVID-19 complications, due to a hypersensitivity reaction to the viral antigens. The production of COVID-19 virus antigen specific IgE has an important role in post-infection allergy as well as its relation to other factors like IL-5 in patients’ sera.
Pendulum Leptogenesis
Creators: name: Bamba, Kazuharu
name: Barrie, Neil D.
name: Sugamoto, Akio
name: Takeuchi, Tatsu
name: Yamashita, Kimiko
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a new non-thermal Leptogenesis mechanism that takes place during the reheating epoch, and utilizes the Ratchet mechanism. The interplay between the oscillation of the inflaton during reheating and a scalar lepton leads to a dynamical system that emulates the well-known forced pendulum. This is found to produce driven motion in the phase of the scalar lepton which leads to the generation of a non-zero lepton number density that is later redistributed to baryon number via sphaleron processes. This model successfully reproduces the observed baryon asymmetry, while simultaneously providing an origin for neutrino masses via the seesaw mechanism.
description: 14 pages, no figures; minor revision to match PLB
Variety Mutations in the Genes of Hereditary Tumor Syndromes in Pancreatic Cancer
Creators: name: E.A. Kolesnikova
name: A.M. Danishevich
name: N.A. Bodunova
name: E.S. Nikiforova
name: P.A. Shatalov
name: I.S. Shumskaya
name: P.A. Malinina
name: S.V. Gamayunov
name: I.E. Khatkov
name: D.M. Kuchin
name: N.M. Kiselev
name: V.E. Zagainov
Publisher: name: Opera Medica et Physiologica
Year: 2024
Subjects: pancreatic cancer
hereditary tumor syndromes
molecular genetic diagnosis
next-generation sequenc-ing
BRCA1/2.

description: Pancreatic cancer (PC) is one of the most aggressive malignant neoplasms. Next-generation sequencing (NGS) was performed in 223 patients from Nizhny Novgorod with morphologically verified pancreatic cancer (PC) treated at the Oncological Dispensary of the Nizhny Novgorod Region in 2021-2022. The patients were conditionally divided into two subgroups: The first subgroup (184 patients) underwent PCR testing at the Nizhny Novgorod Regional Oncology Dispensary and then next-generation sequencing (NGS) of the coding regions of the BRCA1/2 genes at the National Medical Research Centre of Radiology of the Ministry of Health of the Russian Federation. The second sub-group (39 patients) underwent NGS of the coding regions of cancer-associated genes at the Centre for Personalised Medicine of the Moscow Clinical Scientific and Practical Centre named after A.S. Loginov. Germline mutations in the BRCA1/2 genes were detected in 6 patients with pancreatic cancer (3.3 ± 1.3%), including one case in the BRCA1 gene and 5 in the BRCA2 gene. Various pathogenic mutations in genes (ATM, FANCC, POLE, NBN, BLM, SMARCA4, MUTYH, FANCG) associated with different oncological syndromes were found in 9 patients (23.1 ± 1.2%). The high prevalence rates of different pathogenic variants in PC patients, regardless of age and family history of oncology, indi-cate the need for medical genetic counselling followed by NGS. The detection of germline mutations in genes of hered-itary tumour syndromes in PC patients will help to identify high-risk groups for tumor development in relatives and enable early diagnosis.
Additional file 1: of Emissions of nitrous oxide (N2O) from soil surfaces and their historical changes in East Asia: a model-based assessment
Creators: name: Ito, Akihiko
name: Nishina, Kazuya
name: Ishijima, Kentaro
name: Hashimoto, Shoji
name: Inatomi, Motoko
Publisher: name: figshare
Year: 2018
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Figure S1. Cropland fraction in East Asia derived from Hurtt et al. (2011). Figure S2. Comparison between the simulated monthly N2O emissions and observed atmospheric N2O concentrations in East Asia. The observational data were obtained from the World Data Center of Greenhouse Gases ( https://gaw.kishou.go.jp/ ). Figure S3. Comparison of the VISIT estimations (EX0) with the estimates of Hashimoto (2012, updated). (a) Annual N2O emissions and (b) grid-based scatter diagram. Orange line shows linear regression (y [N2O emissions by VISIT] = 1.25 x [N2O emissions by Hashimoto (2012)] + 0.0596, in kg N2O ha− 1 yr.− 1; R2 = 0.44). (DOCX 1792 kb)
Emotion-Recognition Using Smart Watch Sensor Data: Mixed-Design Study
Creators: name: Quiroz, Juan C.
name: Geangu, Elena
name: Yong, Min Hooi
Publisher: name: arXiv
Year: 2018
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: This study investigates the use of movement sensor data from a smart watch to infer an individual's emotional state. We present our findings on a user study with 50 participants. The experimental design is a mixed-design study; within-subjects (emotions; happy, sad, neutral) and between-subjects (stimulus type: audio-visual "movie clips", audio "music clips"). Each participant experienced both emotions in a single stimulus type. All participants walked 250m while wearing a smart watch on one wrist and a heart rate monitor strap on their chest. They also had to answer a short questionnaire (20 items; PANAS) before and after experiencing each emotion. The heart rate monitor served as supplementary information to our data. We performed time-series analysis on the data from the smart watch and a t-test on the questionnaire items to measure the change in emotional state. The heart rate data was analyzed using one-way ANOVA. We extracted features from the time-series using sliding windows and used the features to train and validate classifiers that determined an individual's emotion. Participants reported feeling less negative affect after watching sad videos or after listening to the sad music, P < .006. For the task of emotion recognition using classifiers, our results show that the personal models outperformed personal baselines, and achieved median accuracies higher than 78% for all conditions of the design study for the binary classification of happiness vs sadness. Our findings show that we are able to detect the changes in emotional state with data obtained from the smartwatch as well as behavioral responses.
description: Published in JMIR Mental Health
Towards a Green Economy: Multisectoral Assessment of Renewable Energy Expansion and Input-Output Analysis of the Dominican Energy Matrix
Creators: name: Cornielle, Fernando
Publisher: name: Zenodo
Year: 2024
Subjects: MARIO
Energy Modeling Planning
EMP-LAC

description: This study takes a multisectoral approach to analyze the projected changes in the energy generation matrix of the Dominican Republic by the year 2035. It examines various scenarios that emphasize the transition from fossil fuel-dominated electricity generation to a more sustainable energy system with a greater reliance on non-fossil sources. The main objective is to explore the potential impacts of this transition within the country's energy context, greenhouse gas emissions, and sustainable development and climate change mitigation goals. By integrating data from reliable sources such as CEPAL, Eora, Our World in Data, and the Coordinating Body, the study aims to provide a comprehensive view of the evolution of the energy sector, considering interactions and repercussions across various sectors. The purpose is to offer valuable insights for policy formulation, strategic planning, and investment decisions in the energy sector, aligning the analysis with global efforts towards greener economies and the national strategy for a sustainable energy future.
Nonequilibrium Magnetic Oscillation with Cylindrical Vector Beams
Creators: name: Fujita, Hiroyuki
name: Sato, Masahiro
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Magnetic oscillation is a generic property of electronic conductors under magnetic fields and widely appreciated as a useful probe of their electronic band structure, i.e., the Fermi surface geometry. However, the usage of the strong static magnetic field makes the measurement insensitive to the magnetic order of the target material. That is, the magnetic order is anyhow turned into a forced ferromagnetic one. Here we theoretically propose an experimental method of measuring the magnetic oscillation in a magnetic-order-resolved way by using the azimuthal cylindrical vector (CV) beam, an example of topological lightwaves. The azimuthal CV beam is unique in that when focused tightly, it develops a pure longitudinal magnetic field. We argue that this characteristic focusing property and the discrepancy in the relaxation timescale between conduction electrons and localized magnetic moments allow us to develop the nonequilibrium analog of the magnetic oscillation measurement. Our optical method would be also applicable to metals the under ultra-high pressure of diamond anvil cells.
description: 8 pages, 4 figures
Generation and characterisation of anti-dengue monoclonal antibodies in a case of severe primary dengue infection
Creators: name: Roberts, Catherine
Publisher: name: Imperial College London
Year: 2015

description: Introduction Dengue is one of the most important emerging infections with 50% of the world’s population living in dengue endemic countries. The clinical spectrum of disease can range from asymptomatic to a severe haemorrhagic illness. Those with secondary infection with a second serotype are most at risk of severe disease. This has lead to the theory that a primed immune response ineffectively clears a secondary infection and enhances infection. Teasing out immunology to dengue has become important in aiding effective and safe vaccine design. In this project, I investigated the antibody response of a case of acute severe primary dengue. Methods Activated B cells were isolated from a patient with acute severe dengue virus. Recombinant monoclonal antibodies (mAbs) were produced and investigated. The mAbs were assessed for: their ability to recognise dengue; epitopes to which they bind; which amino acids of the structural proteins they bind to. Results 88 IgH-Igλ and 44 IgH-Igκ recombinant IgG antibodies were produced. 44 mAbs were investigated further. Seven of the mAbs showed reactivity to dengue, 3 reacting to dengue 1 alone, 3 had cross reactivity to all four serotypes and JE. Western blot revealed that no antibodies bound to prM or E. A viral like protein (VLP) library was created for further assessment of epitope binding. Discussion IgG was produced to dengue despite the early time point. Interestingly 43% (n=3) of antibodies were specific to the infecting dengue serotype, but a further 43% were reactive to all four dengue serotypes. The epitopes for these mAbs were not demonstrated. This may be due to changes to the E and prM proteins during the Western blot that mAbs recognise other epitopes or else the mAbs react to tertiary structure epitopes. Use of the VLP library to identify the amino acid residues necessary for binding would help in understanding the epitopes.
Oscillating solutions of the matter density contrast in Horndeski's theory
Creators: name: Matsumoto, Jiro
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Evolution of the large scale structure of the Universe is described by galaxy bias and the growth rate function of the matter density contrast. The behavior of the growth rate function, in general, depends on the types of dark energy or modified gravity theories, because they modify Poisson's equation for gravity by changing the Newtonian constant in the quasi-static solutions. Whereas, another mode of the matter density contrast "oscillating mode" has not been studied well, although there is a possibility that it drastically changes the gravitational law. In this paper, we will construct the way to investigate oscillating solutions and show the concrete forms of the solutions by using the WKB approximation.
description: 21 pages, 6 figures. References added, sentences and expressions polished, version to appear in JCAP
Implementation of a multidisciplinary high-fidelity in-situ postpartum hemorrhage simulation: assessing simulation quality and offering recommendations for systems change
Creators: name: Gilbert, Imaude
Publisher: name: No Publisher Supplied
Year: 2024

description: Project Purpose: The purpose of this quality improvement project was to implement a multidisciplinary postpartum hemorrhage (PPH) simulation, assess the quality of the simulation used, identify system gaps, and provide recommendations regarding how to close those site/system-specific gaps at a central New Jersey academic medical center.Methodology: A PPH simulation to include blood transfusion was developed based on the California Maternal Quality Care Collaborative Uterine Atony/Obstetric Hemorrhage Toolkit. Upon project implementation, Likert scale questions from the Simulation Design Scale assessed simulation quality and solicited qualitative data surrounding identification of system gaps based on two open-ended responses from participants.Results: Ten nurses and one clinical care technician participated in the project. The findings suggest simulation fidelity mattered most to participants but there was not enough time to set goals for the patient during the simulation. The primary response received from the open-ended questionnaire surrounding system/communication barriers included miscommunication that delayed pertinent care. Implications for Practice: Recommendations to address clinical practice and systems gaps include establishing a policy that requires perinatal providers (doctors, nurses, clinical care technicians, pharmacists, and lab technicians) to participate in annual mandatory simulation, debriefing and ongoing systems assessment.
The number of valid factorizations of Fibonacci prefixes
Creators: name: Bonardo, Pierre
name: Frid, Anna E.
name: Shallit, Jeffrey
Publisher: name: arXiv
Year: 2018
Subjects: subject: Combinatorics (math.CO)
subject: Formal Languages and Automata Theory (cs.FL)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 68R15, 11B39

description: We establish several recurrence relations and an explicit formula for V(n), the number of factorizations of the length-n prefix of the Fibonacci word into a (not necessarily strictly) decreasing sequence of standard Fibonacci words. In particular, we show that the sequence V(n) is the shuffle of the ceilings of two linear functions of n.
description: Version accepted to Theoretical Computer Science
Static spherically symmetric solutions in higher derivative gravity
Creators: name: Perkins, Alun
Publisher: name: Imperial College London
Year: 2016

description: We consider the four-derivative modification to the Einstein-Hilbert action of general relativity, without a cosmological constant. Higher derivative terms are interesting because they make the theory renormalisable (but non-unitary) and because they appear generically in quantum gravity theories. We consider the classical, static, spherically symmetric solutions, and try to enumerate all solution families. We find three families in expansions around the origin: one corresponding to the vacuum, another which contains the Schwarzschild family, and another which does not appear in generic theories with other number of derivatives but seems to be the correct description of solutions coupled to positive matter in the four-derivative theory. We find three special families in expansions around a non-zero radius, corresponding to normal horizons, wormholes and exotic horizons. We study many examples of matter-coupled solutions to the theory linearised around flat space, which corroborate our arguments. We are assisted by use of a "no-hair" theorem that certain conditions imply that $R=0$, which is applicable in many cases including asymptotically flat space-times with horizons. The Schwarzschild black hole still exists in the theory, but a second branch of black hole solutions is found that can have both positive and negative mass, and that coincide with the Schwarzschild black holes at a single mass. The space of asymptotically flat solutions is probed numerically by shooting inwards from a weak-field solution at large radius, and the behaviour at small radius is classified into the families of series solutions (most of which make an appearance). The results are inconclusive but show several interesting features for further study.
MPEC 2024-G115 : 2017 HS
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.