cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
NAD(P)H fluorescence lifetime imaging of live intestinal nematodes reveals metabolic crosstalk between parasite and host
Creators: name: Liublin, Wjatscheslaw
name: Rausch, Sebastian
name: Leben, Ruth
name: Lindquist, Randall L.
name: Fiedler, Alexander
name: Liebeskind, Juliane
name: Beckers, Ingeborg E.
name: Hauser, Anja E.
name: Hartmann, Susanne
name: Niesner, Raluca A.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Biological fluorescence
subject: Biophysics
subject: Immunology
subject: FOS: Clinical medicine
subject: Infection
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites. Thus, it is key to understand how intestinal nematodes arrive and persist in their luminal niche and interact with the host over long periods of time. One basic mechanism governing parasite and host cellular and tissue functions, metabolism, has largely been neglected in the study of intestinal nematode infections. Here we use NADH (nicotinamide adenine dinucleotide) and NADPH (nicotinamide adenine dinucleotide phosphate) fluorescence lifetime imaging of explanted murine duodenum infected with the natural nematode Heligmosomoides polygyrus and define the link between general metabolic activity and possible metabolic pathways in parasite and host tissue, during acute infection. In both healthy and infected host intestine, energy is effectively produced, mainly via metabolic pathways resembling oxidative phosphorylation/aerobic glycolysis features. In contrast, the nematodes shift their energy production from balanced fast anaerobic glycolysis-like and effective oxidative phosphorylation-like metabolic pathways, towards mainly anaerobic glycolysis-like pathways, back to oxidative phosphorylation/aerobic glycolysis-like pathways during their different life cycle phases in the submucosa versus the intestinal lumen. Additionally, we found an increased NADPH oxidase (NOX) enzymes-dependent oxidative burst in infected intestinal host tissue as compared to healthy tissue, which was mirrored by a similar defense reaction in the parasites. We expect that, the here presented application of NAD(P)H-FLIM in live tissues constitutes a unique tool to study possible shifts between metabolic pathways in host-parasite crosstalk, in various parasitic intestinal infections.
Community care coordination for stroke survivors: results of a complex intervention study
Creators: name: Deutschbein, Johannes
name: Grittner, Ulrike
name: Schneider, Alice
name: Schenk, Liane
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Care coordination
subject: Stroke
subject: Health care utilization
subject: Readmissions
subject: Costs
subject: Germany
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Outpatient follow-up care for stroke survivors is often inadequate and mostly self-organized by the patients themselves. In the German health care system, there are no standard care programs for patients after they are discharged from the hospital to support them with their multifaceted and heterogeneous health care needs. The objective of this complex intervention study was to evaluate the effectiveness of a post-stroke care coordination program in comparison to standard care in the first year after a stroke. Methods: Patients aged 55 and older who had survived a stroke or a transient ischemic attack (TIA) within the last 6 months before enrollment were included. Participants received care coordination either by telephone or face-to-face for up to 1 year. Patients’ health insurance claims data were used to measure outcomes. The control group consisted of stroke survivors receiving standard care and was constructed by exact matching based on six criteria. Outcome measures were health services utilization, rate of recurrent events, readmissions and accompanying costs, and mortality. Outcomes were tested using different multiple models. Results: In total, N = 361 patients were included in the analyses. Intervention participants had seen an outpatient neurologist more often (OR = 4.75; 95% CI: 2.71–8.31) and were readmitted to a hospital less frequently (IRR = 0.42; 95% CI: 0.29–0.61), resulting in lower hospital costs (IQR = €0–1910 in the intervention group, IQR = €0–4375 in the control group). There were no substantial group differences in the rate of recurrent events and mortality. Conclusion: This study showed the beneficial potential of care coordination for a vulnerable patient population: the utilization rate of important health services was increased, and the rate of hospital readmissions decreased as a result. Future research should focus on the risk of recurrent strokes and the long-term effects of improved care. Trial registration: DRKS00017526 on DRKS – German Clinical Trials Register (retrospectively registered: 21 June 2019).
Full quantum control of enantiomer-selective state transfer in chiral molecules despite degeneracy
Creators: name: Leibscher, Monika
name: Pozzoli, Eugenio
name: Pérez, Cristobal
name: Schnell, Melanie
name: Sigalotti, Mario
name: Boscain, Ugo
name: Koch, Christiane P.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Applied mathematics
subject: Atomic and molecular interactions with photons
subject: Circular dichroism
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: The driven quantum asymmetric top is an important paradigm in molecular physics with applications ranging from quantum information to chiral-sensitive spectroscopy. A key prerequisite for these applications is the ability to completely control the rotational dynamics. The inherent degeneracy of quantum rotors poses a challenge for quantum control since selecting a particular rotational state cannot be achieved by spectral selection alone. Here, we prove complete controllability for rotational states of an asymmetric top belonging to degenerate values of the orientational quantum number M. Based on this insight, we construct a pulse sequence that energetically separates population in degenerate M-states. Introducing the concept of enantio-selective controllability, we determine the conditions for complete enantiomer-specific population transfer in chiral molecules and construct pulse sequences for the example of propanediol and carvone molecules for population initially distributed over degenerate M-states. Our work shows how to leverage controllability analysis for the solution of practical quantum control problems.
Modeling hourly weather-related road traffic variations for different vehicle types in Germany
Creators: name: Becker, Nico
name: Rust, Henning W.
name: Ulbrich, Uwe
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Road traffic
subject: Traffic volume
subject: Count data
subject: Weather
subject: Germany
subject: Poisson regression
subject: Prediction
subject: Vehicle type
subject: Motorbikes
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::551 Geologie, Hydrologie, Meteorologie

description: Weather has a substantial influence on people’s travel behavior. In this study we analyze if meteorological variables can improve predictions of hourly traffic counts at 1400 stations on federal roads and highways in Germany. Motorbikes, cars, vans and trucks are distinguished. It is evaluated in how far the mean squared error of Poisson regression models for hourly traffic counts is reduced by using precipitation, temperature, cloud cover and wind speed data. It is shown that in particular motorbike counts are strongly weather-dependent. On federal roads the mean squared error is reduced by up to 60% in models with meteorological predictor variables, when compared to models without meteorological variables. A detailed analysis of the models for motorbike counts reveals non-linear relationships between the meteorological variables and motorbike counts. Car counts are shown to be specifically sensitive to weather in touristic regions like seaside resorts and nature parks. The findings allow for several potential applications like improvements of route planning in navigation systems, implementations in traffic management systems, day-ahead planning of visitor numbers in touristic areas or the usage in road crash modelling.
Additional file 1 of Improving the sexual health of women with disabilities in sub-Saharan Africa: a scoping review of published studies
Creators: name: Bolarinwa, Obasanjo Afolabi
name: Odimegwu, Clifford
name: Tapera, Talent
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1.
The majority of β-catenin mutations in colorectal cancer is homozygous
Creators: name: Arnold, Alexander
name: Tronser, Moritz
name: Sers, Christine
name: Ahadova, Aysel
name: Endris, Volker
name: Mamlouk, Soulafa
name: Horst, David
name: Möbs, Markus
name: Bischoff, Philip
name: Kloor, Matthias
name: Bläker, Hendrik
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Colorectal cancer (CRC)
subject: ß-catenin (CTNNB1)
subject: E-cadherin
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: β-catenin activation plays a crucial role for tumourigenesis in the large intestine but except for Lynch syndrome (LS) associated cancers stabilizing mutations of β-catenin gene (CTNNB1) are rare in colorectal cancer (CRC). Previous animal studies provide an explanation for this observation. They showed that CTNNB1 mutations induced transformation in the colon only when CTNNB1 was homozygously mutated or when membranous β-catenin binding was hampered by E-cadherin haploinsufficiency. We were interested, if these mechanisms are also found in human CTNNB1 mutated CRCs. Results: Among 869 CRCs stabilizing CTNNB1 mutations were found in 27 cases. Homo- or hemizygous CTNNB1 mutations were detected in 74% of CTNNB1 mutated CRCs (13 microsatellite instabile (MSI-H), 7 microsatellite stabile (MSS)) but only in 3% (1/33) of extracolonic CTNNB1 mutated cancers. In contrast to MSS CRC, CTNNB1 mutations at codon 41 or 45 were highly selected in MSI-H CRC. Of the examined three CRC cell lines, β-catenin and E-cadherin expression was similar in cell lines without or with hetereozygous CTNNB1 mutations (DLD1 and HCT116), while a reduced E-cadherin expression combined with cytoplasmic accumulation of β-catenin was found in a cell line with homozygous CTNNB1 mutation (LS180). Reduced expression of E-cadherin in human MSI-H CRC tissue was identified in 60% of investigated cancers, but no association with the CTNNB1 mutational status was found. Conclusions: In conclusion, this study shows that in contrast to extracolonic cancers stabilizing CTNNB1 mutations in CRC are commonly homo- or hemizygous indicating a higher threshold of β-catenin stabilization to be required for transformation in the colon as compared to extracolonic sites. Moreover, we found different mutational hotspots in CTNNB1 for MSI-H and MSS CRCs suggesting a selection of different effects on β-catenin stabilization according to the molecular pathway of tumourigenesis. Reduced E-cadherin expression in CRC may further contribute to higher levels of transcriptionally active β-catenin, but it is not directly linked to the CTNNB1 mutational status.
Group hypnosis for stress reduction and improved stress coping: a multicenter randomized controlled trial
Creators: name: Fisch, Silvia
name: Trivaković-Thiel, Suzana
name: Roll, Stephanie
name: Keller, Theresa
name: Binting, Sylvia
name: Cree, Margit
name: Brinkhaus, Benno
name: Teut, Michael
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Hypnosis
subject: Hypnotherapy
subject: Stress reduction
subject: Stress coping
subject: Group program
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: The aim of the trial was to investigate the effect of a hypnotherapeutic group program in healthy persons with increased levels of perceived stress. Methods: In a randomized controlled multicenter trial participants with a self-assessed subjective stress level ≥ 40 mm on a visual analogue scale (0–100 mm; VAS) for the previous week and a stable state of health were randomized to either 5 weekly sessions of 120-min duration of a hypnotherapeutic group program for stress reduction and improved stress coping plus 5 hypnosis audiorecords for individual practice at home plus an educational booklet for stress coping (hypnosis group) versus an educational booklet only (control group). The primary outcome parameter was the VAS stress level for the previous week after 5 weeks. Secondary outcome parameters included the VAS stress level after 12 weeks, perceived stress (CPSS), depression (ADS-K), self efficacy (SWE) and quality of life (SF 36) after 5 weeks and 12 weeks. Analysis of covariance with a significance level of 5% using the full analysis set was used for analysis; the model included treatment (fixed effect), VAS baseline value (fixed covariate), and center (random effect). Results: A total of 95 participants were randomized; 47 (40 female, 45 ± 13.4 years of age) were allocated to the hypnosis group, and 48 (41 female, 46.9 ± 14.3 years) were allocated to the control group. Regarding VAS stress level after 5 weeks, the adjusted VAS mean in the hypnosis group was 41.8 mm [95% confidence interval (CI): 35.2; 48.4] compared to 62.9 mm [56.2; 69.7] in the control group, and the group difference was − 21.2 mm [− 30.1; − 12.2] (P
title: Millennial variability, hydrological and limnological changes during MIS3-2 in Lake Petén Itzá, Guatemala
Creators: name:  Martinez-Abarca,  Rodrigo
name:  Abstein ,  Michelle
name:  Hoelzmann  ,  Philipp
name:  Bauersachs  ,  Thorsten
name:  Pérez   ,  Liseth
name:  Stockhecke  ,  Mona
name:  Cohuo Duran ,  Sergio
name:  Schwalb ,  Antje
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Heinrich Stadials and Greenland Interstadials are abrupt climate variations that are observed in the Northern Hemisphere throughout Marine Isotopic Stages (MIS) 3-2. Lake Petén Itzá, northern Guatemala, is a key site for paleoclimate investigations due to its sensitivity to changes in climate forcing such as the Intertropical Convergence Zone (ITCZ) and the Atlantic Meridional Overturning Circulation (AMOC). In this study, we reconstructed the hydrology and limnology of Lake Petén Itzá during MIS3-2 based on geochemical and mineralogical evidence from the PI-2 record. The beginning of MIS3 (58-52.5 ka cal BP) is characterized by wet conditions, with high lake productivity and anoxic bottom waters that prevailed in the following period (52.5-39 ka cal BP) although with a slight decrease in runoff. During the transition of MIS3 to MIS2 (39-23 ka cal BP) the evaporation in the lake increased considerably, the contribution of aquatic organic matter decreased and bottom waters became more oxic. These conditions reversed during the Last Glacial Maximum (23-18 ka cal BP) when runoff, lake productivity and anoxic conditions in the bottom waters reached their maximum. We have updated the chronology of PI-2 and re-identified Heinrich Stadials (HS) 5-1 signals based in lithological and geochemical variations. We suggest that HS5, HS4 and HS3 were wetter than HS2 and HS1 and likely associated with the strengthening of the trade winds and an intensification of the AMOC which promoted moisture transport and precipitation in the Caribbean region and Gulf of Mexico. On the other hand, we identified 14 Greenland Interstadials (GI) as maximum values of Ca/Ti+Al+Fe. GIs were characterized by high evaporation in the lake and dry conditions. This is explained as a consequence of southern migration in the average ITCZ position.
A Qualitative Study of Self and Caregiver Perspectives on How Autistic Individuals Cope With Trauma
Creators: name: Ng-Cordell, Elise
name: Rai, Anika
name: Peracha, Hira
name: Garfield, Tamara
name: Lankenau, Stephen E.
name: Robins, Diana L.
name: Berkowitz, Steven J.
name: Newschaffer, Craig
name: Kerns, Connor M.
Publisher: name: The University of British Columbia
Year: 2023

description: Background: Coping can moderate the relationship between trauma exposure and trauma symptoms. There are many conceptualisations of coping in the general population, but limited research has considered how autistic individuals cope, despite their above-average rates of traumatic exposure. Objectives: To describe the range of coping strategies autistic individuals use following traumatic events. Methods: Fourteen autistic adults and 15 caregivers of autistic individuals, recruited via stratified purposive sampling, completed semi-structured interviews. Participants were asked to describe how they/their child attempted to cope with events they perceived as traumatic. Using an existing theoretical framework and reflexive thematic analysis, coping strategies were identified, described, and organized into themes. Results: Coping strategies used by autistic individuals could be organized into 3 main themes: (1) Engaging with Trauma, (2) Disengaging from Trauma, and (3) Self-Regulatory Coping. After the three main themes were developed, a fourth integrative theme, Diagnostic Overshadowing, was created to capture participants' reports of the overlap or confusion between coping and autism-related behaviors. Conclusions: Autistic individuals use many strategies to cope with trauma, many of which are traditionally recognized as coping, but some of which may be less easily recognized given their overlap with autism-related behaviors. Findings highlight considerations for conceptualizing coping in autism, including factors influencing how individuals cope with trauma, and how aspects of autism may shape or overlap with coping behavior. Research building on these findings may inform a more nuanced understanding of how autistic people respond to adversity, and how to support coping strategies that promote recovery from trauma.
Leaving: A memoir
Creators: name: Guntarik, Olivia
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 360201
subject: Creative writing (incl. scriptwriting)

description: BACKGROUND The essay, Leaving: A memoir (part of a much larger family memoir-in-progress) was published in the highly respected quarterly literary journal, Kill Your Darlings. The work provides an assault to media fixations on the migrant that emerge as monolithic symbols of violence and victimhood. It is an attempt to speak back to gendered and racialised stereotypes of 'the other'. Authors such as Raimond Gaita, Kristina Olssen and Mammad Aidani have adopted a similar 'memoirist' approach to narrating social history. Like theirs, this work acts as a cultural artefact, a first-person narrative that will be formative in describing new generations of migrants in Australia. CONTRIBUTION This work about a family's story of migration to Australia forms part of the social history fabric of Victoria in the 1970s. During this period, the dominant narrative was of refugees fleeing the Indochina War and Khmer Rouge regime from countries such as Vietnam and Kampuchea. While these histories are significant to our understanding of migration, Leaving presents an alternative story of migrant resettlement from a region of south-east Asia often overlooked in popular and scholarly engagements on migration - Borneo. The recounting of this family's journey reworks archival material to present the hidden dimensions of history in a more familiar narrative form for diverse audiences. This work represents an innovative alternative to foreground migrant diversity and the diasporic nature of displacement for this region. The work acts as a 'cross over text' that merges academic scholarship with popular forms. SIGNIFICANCE Recognised through a manuscript sponsorship award from the University of Melbourne Writing Centre for Scholars and Researchers, and an Australian Society of Authors' mentorship award, as one of '15 writers of great promise' selected from 209 eligible entries in 2010. The award winning essay forms part of the permanent collection of Melbourne's Immigration Museum.
Additional file 1 of The mode of action of IL-23 in experimental inflammatory arthritic pain and disease
Creators: name: Lee, Kevin M.-C.
name: Lupancu, Tanya
name: Chang, Leon
name: Manthey, Carl L.
name: Zeeman, Martha
name: Fourie, Anne M.
name: Hamilton, John A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 1
title: Unpacking form-based codes in a British Columbia planning context
Creators: name: Bell, Kristina
Publisher: name: Electronic version published by Vancouver Island University
Year: 2022
Subjects: subject: Zoning--British Columbia
subject: Land use--British Columbia

description: There is consensus amongst the critics of Euclidean zoning that the tool has produced undesirable, unsustainable, and inequitable places. However, without the existence of a revised zoning framework, a major issue in our land-use planning today is that we have modern goals of sustainable design, compact development, and equitable policy while using a regulatory tool that is based on outdated principles. Form-based codes (FBCs) have been advertised as the answer to our planning problems, yet there has been little uptake in British Columbia. This thesis explores the debate around zoning reform, and more specifically, form-based zoning. The research explores the applicability of FBCs to British Columbia planning by taking a legal perspective on the limits to the zoning power under the Local Government Act and explores whether local governments are approximating FBCs. By conducting a comparative case study analysis between Seaside, Florida and Whistler, British Columbia, this research finds that while the BC municipality may be approximating an FBC with other regulatory methods, these tools are inconsistent in achieving central goals of the FBC movement and add to an already complex development process. The study concludes with key learnings and recommendations on how to best move forward with zoning in British Columbia.
Diagnostic divergence based on z-score models in the evaluation of patients with connective tissue disorders
Creators: name: Coca Frias, Enrique
name: Madriago, Erin
name: Markwardt, Sheila
name: Huang, Jennifer H.
name: Parker, Julia
name: Holmes, Kathryn W.
Publisher: name: Oregon Health and Science University
Year: 2024
Subjects: subject: Bicuspid Aortic Valve Disease
subject: Connective Tissue
subject: Marfan Syndrome
subject: Echocardiography
subject: aortopathy
subject: connective tissue disorders
subject: z-score

description: Z-score models in pediatric echocardiographic studies are pivotal in medical decision making in patients with concern for aortopathies. An aortic root Z score > 2 may prompt genetic testing or a clinical diagnosis of Marfan if Z >3. This study sought to determine if there was a significant difference between Boston (BTN) and Pediatric Heart Network (PHN) allometric Z-score models in patients referred for aortopathy with or without connective tissue disorders (CTD).
Supplementary document for Opto-thermophoretic trapping of micro and nanoparticles with a 2 μm Tm-doped fiber laser - 5515131.pdf
Creators: name: Mamuti, Roukuya
name: Fuji, Takao
name: Kudo, Tetsuhiro
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Classical and Physical Optics

description: Supplemental Information 1 to 7
Cleopomiarus caucasicus Caldara and Legalov 2016
Creators: name: Gültekin, Neslihan
name: Caldara, Roberto
name: Gültekin, Levent
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Cleopomiarus
Cleopomiarus caucasicus

description: Cleopomiarus caucasicus Caldara and Legalov, 2016  (Figs. 3A–C)
 Material Examined. TURKEY: Trabzon Prov., Zigana Mountain, Hamsiköy, Zitaş Road, 40°40′21′′N, 39°26′05′′E, 1,700 m, 14.7.201 9, 5♂, 4♀, N. GÜltekin leg.
 Diagnosis. Length 2.7–3.7 mm. Vestiture on dorsum comprising subrecumbent to suberect, whitish to light brown, seta-like scales. Rostrum in male nearly as long as pronotum, in female longer than pronotum, moderately curved in lateral view. Pronotum transverse, subconical, with rounded sides. Elytra globose, short, slightly longer than wide, at base moderately directed forward from interstria 5 to humeri, with somewhat rounded sides. Mesofemur with minute tooth, metafemur with distinct tooth, uncus of metatibia in male with apex enlarged and directed outward. Body of penis narrowed at middle third.
 Remarks. This taxon is closely related to Cleopomiarus graminis (Gyllenhal, 1813), a species with very wide Palearctic distribution but unknown from Turkey until now (Caldara and Legalov 2016). From C. graminis, C. caucasicus differs in the metatibial uncus of the male ending with a broad apex and the shape of the penis, especially at its more pointed apical part. In Turkey C. caucasicus may be confused with C. distinctus (see Remarks under that species).
 Distribution. Armenia (Alonso-Zarazaga et al. 2017; Caldara and Legalov 2016). Turkey, present finding; this is a new record for the fauna of Turkey.
 Plant Association. Campanula trachelium (Fig. 3D), with a wide Eurasian distribution, was determined as the host plant of C. caucasicus for the first time, in fact representing the first host plant record for this weevil species.
description: Published as part of Gültekin, Neslihan, Caldara, Roberto & Gültekin, Levent, 2021, Miarus Schoenherr and Cleopomiarus Pierce (Coleoptera: Curculionidae) Species Associated with Campanula L. (Campanulaceae) Plants in the Eastern Black Sea Region of Turkey, pp. 505-511 in The Coleopterists Bulletin 75 (3) on page 510, DOI: 10.1649/0010-065X-75.3.505, http://zenodo.org/record/13251631
A case of Streptococcus canis bacteremia, osteomyelitis, sacroiliitis, myositis, and abscess
Creators: name: Van Tol, A. L.
name: Tang, B.
name: Mackie, I. D.
Publisher: name: BioMed Central
Year: 2022

description: Background: Streptococcus canis is a group G beta-hemolytic Streptococcus species which normally resides on the skin and mucosal surfaces of dogs. Although it rarely causes infection in humans, our case and review of relevant literature demonstrate that this multi-host pathogen may be responsible for metastatic infection. We present an appropriate management strategy in such cases. Case presentation: A previously healthy 26-year-old male presented to the emergency department with a 2-day history of erythema, pain, and swelling of the left ankle and foot, consistent with acute cellulitis. The patient was initially discharged home with a plan to complete a course of IV cefazolin as an outpatient, but later recalled after two sets of blood cultures grew gram positive cocci. Blood cultures speciated as Streptococcus canis. This was performed by identifying beta hemolytic strep on blood agar, then typed as Lancefield group G, followed by MALDI-TOF which distinguished S. canis. History was unremarkable except for a 2-week history of lower back pain precipitated by a wrestling injury. There was no canine bite or scratch wound, although the patient lives with a dog. CT spine was obtained which demonstrated right piriformis myositis and S1 osteomyelitis. MRI additionally demonstrated right erector spinae myositis, right sacroiliitis, and multiple collections in the right posterior paraspinal soft tissues. Transthoracic echocardiogram did not demonstrate valvular vegetations. The S. canis isolate was pan-susceptible and the patient was ultimately discharged home and completed a 8-week course of IV penicillin G. After completion of therapy, his symptoms, repeat imaging, and biochemical markers suggested resolution of infection on follow-up. Conclusions: We suggest that management of S. canis bacteremia should involve consideration of screening for metastatic infection and infectious diseases consultation. However, despite its potential for systemic involvement, S. canis is often susceptible to narrow spectrum antibiotics, and may be treated with penicillins. Key Points 1. S. canis does not require a clear portal of entry to cause infection 2. When S. canis infection is identified, screening for sites of metastatic infection should be considered 3. S. canis infection is typically susceptible to narrow-spectrum antibiotics
Adjustable Rate Mortgages Analytics
Creators: name: Lee, David
Publisher: name: Zenodo
Year: 2022
Subjects: Adjustable rate mortgages, ARMs

description: Adjustable rate mortgages (ARMs) model has a significant amount of parameter/model risk In particular, there are many input parameters (many of them market variables) and functions of these parameters that can have add a significant amount of risk.
description: https://osf.io/preprints/socarxiv/y43dx/download
ANALYSING CAUSES AND EFFECTS OF DELAYIN LEGEDADI DEEP WELLS WATER SUPPLY DESIGN ANDCONSTRUCTION PROJECT (I)
Creators: name: ZELALEM TSEGAYE ASMARE
Publisher: name: Zenodo
Year: 2018

description: ANALYSING CAUSES AND EFFECTS OF DELAYIN 

LEGEDADI DEEP WELLS WATER SUPPLY 

DESIGN ANDCONSTRUCTION PROJECT (I)
Construction - Spatialised Performance System
Creators: name: Harvey, Lawrence
name: Hannam, Jeffrey
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 330105
subject: Architectural science and technology
classificationCode: 360304
subject: Music performance

description: RESEARCH BACKGROUND: Spatial sound concerts using large-scale sound diffusion systems (up to 32 loudspeakers) are a unique form of public performance. The practice has complex technical, technological, aesthetic, perceptual and artistic requirements to seamlessly deliver concert programs. Only a small number of international electroacoustic studios regularly conduct public concerts at this scale. Since 2008, SIAL Sound Studios and Elision Ensemble have completed research, workshops, software and technical development to deliver Richard Barrett's two-hour composition Construction.

RESEARCH CONTRIBUTION: The final approach involved close integration of a new MAX/MSP platform with a technique for designing; refining and performing 3D-sound trajectories for up to 16 instruments performing simultaneously. The technique allowed complex sound paths to be pre-prepared and further refined in the venue during rehearsals. These refinements took account of acoustic qualities generated through the interaction of the space, the 16-channel sound system, the composition and varying instrumental combinations. Previous to this research, the industry partner could only perform with a limited number of channels under basic real-time control. This research produced a method to construct and control complex spatial sound trajectories and apply them to individual instrumental streams, through close collaboration between 3 sound operators and the composer. Audiences can now experience contemporary music performances that surpass existing concert formats involving static instrumental sound sources.

RESEARCH SIGNIFICANCE: Huddersfield Contemporary Music Festival, and Sound and Music UK supported the performance, while pre-performance research and development was supported by the ARC, LP0882872. The concert was broadcast live-to-air on 'Hear and Now', BBC3, 10.30pm 19 November, 2011
Supplementary document for Opto-thermophoretic trapping of micro and nanoparticles with a 2 μm Tm-doped fiber laser - 5515131.pdf
Creators: name: Mamuti, Roukuya
name: Fuji, Takao
name: Kudo, Tetsuhiro
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Classical and Physical Optics

description: Supplemental Information 1 to 7
Große Transformation und die Medien - Alternativen zum Wachstum als Leitbild der Kommunikation
Creators: name: Eick, Martina
name: Zieschank, Roland
name: Ronzheimer, Manfred
Publisher: name: My University
Year: 2017
Subjects: subject: Umweltpolitik
subject: Kommunikation
subject: Wirtschaftswachstum
subject: Große Transformation
subject: Medien
subject: Nachhaltigkeit | Strategien | Internationales

description: Anthropozän: Wir Menschen haben den Planeten und zusehends auch uns selbst um- und überformt, zum Teil bereits über die Ver- und Erträglichkeitsgrenzen hinweg. Rettung muss nun her: Große Transformation, möglichst schnell und nachhaltig. Umsteuern, raus aus den planetaren und sozialen Sackgassen. Wenden bei Energie, Verkehr, Agrar, Wachstum und Forschung, denn ein Weiter so ist Selbstmord. Auch die Medienlandschaft formt sich rasant und tiefgreifend neu, sowohl die Bedingungen für Medienschaffende als auch das Mediennutzerverhalten. Diese Dynamiken waren Thema der hier dokumentierten Tagungsreihe. Unter der Fragestellung, wie kommen Anthropozän und Große Transformation in die Medien, haben Wissenschaftlerinnen und Medienschaffende gemeinsam Verständigungslücken skizziert und Verständigungsbrücken zu bauen versucht. Klar wurde: Wir müssen uns gegenseitig mit passenderen Bauteilen versorgen.
The Influence of Exotic Plant Invasion on Pollinator Abundance
Creators: name: Hill, Maxcy
Publisher: name: QUBES Educational Resources
Year: 2022

description: This lesson introduces two global change factors, natural habitat loss and exotic plant invasion, and analyzes how these stressors impact the biodiversity and abundance of pollinator species. Pearson's correlation coefficient and general linear models are introduced to analyze these relationships, and the creation of graphics are used to visualize these relationships.
Impact of team configuration and team stability on primary care quality
Creators: name: Hysong, Sylvia J
name: Amspoker, Amber B
name: Hughes, Ashley
name: Woodard, Lechauncy
name: Oswald, Frederick L
name: Petersen, Laura A
name: Lester, Houston F
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: Uncategorized

description: BACKGROUND: The science of effective teams is well documented; far less is known, however, about how specific team configurations may impact primary care team effectiveness. Further, teams experiencing frequent personnel changes (perhaps as a consequence of poor implementation) may have difficulty delivering effective, continuous, well-coordinated care. This study aims to examine the extent to which primary care clinics in the Veterans Health Administration have implemented team configurations consistent with recommendations based on the Patient-Centered Medical Home model and the extent to which adherence to said recommendations, team stability, and role stability impact healthcare quality. Specifically, we expect to find better clinical outcomes in teams that adhere to recommended team configurations, teams whose membership and configuration are more stable over time, and teams whose clinical manager role is more stable over time. METHODS/DESIGN: We will employ a combination of social network analysis and multilevel modeling to conduct a database review of variables extracted from the Veterans Health Administration's Team Assignments Report (TAR) (one of the largest, most diverse existing national samples of primary care teams (nteams > 7000)), as well as other employee and clinical data sources. To ensure the examination of appropriate clinical outcomes, we will enlist a team of subject matter experts to select a concise set of clear, prioritized primary care performance metrics. We will accomplish this using the Productivity Measurement and Enhancement System, an evidence-based methodology for developing and implementing performance measurement. DISCUSSION: We are unaware of other studies of healthcare teams that consider team size, composition, and configuration longitudinally or with sample sizes of this magnitude. Results from this study can inform primary care team implementation policy and practice in both private- and public-sector clinics, such that teams are configured optimally, with adequate staffing, and the right mix of roles within the team. TRIAL REGISTRATION: Not applicable-this study does not involve interventions on human participants.
IJTIMOIY KONFORIZM VA SHAXSLARARO XATTI-HARAKAT
Creators: name: Toirova Nilufar Shuxrat qizi.  Toshkent Xalqaro Kimyo universiteti magistranti  E-mail: nilufar7411@mail.ru
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqolada ijtimoiy konforizm tushunchasi, uning shaxs va jamiyat oʻrtasidagi oʻzaro munosabatlardagi roli hamda shaxslararo xatti-harakatlarga taʼsiri tahlil qilingan. Muallif konforizmning ijobiy va salbiy jihatlarini ochib beradi, shaxsning mustaqil fikrlashiga taʼsir etuvchi omillar, jumladan, guruh bosimi, ijtimoiy meʼyorlar va stereotiplar kabi holatlarni koʻrib chiqadi. Maqolada, shuningdek, shaxslararo aloqalarda konforizmning namoyon boʻlish shakllari va uni bartaraf etish yoʻllari haqida fikr yuritiladi. Ilmiy-nazariy tahlillar va amaliy misollar orqali muallif ijtimoiy muomaladagi muvozanatni saqlashda tanqidiy fikrlashning ahamiyatini asoslab beradi.
Protocol for a randomized controlled trial of the Men in Mind training for mental health practitioners to enhance their clinical competencies for working with male clients
Creators: name: Seidler, Zac E.
name: Wilson, Michael J.
name: Toogood, Nicholas W.
name: Oliffe, John Lindsay
name: Kealy, David
name: Ogrodniczuk, John S.
name: Owen, Jesse
name: Mackinnon, Andrew
name: Le, Long Khanh‑Dao
name: Mihalopoulos, Cathrine
name: Pirkis, Jane
name: Rice, Simon
Publisher: name: BioMed Central
Year: 2022

description: Background Although the proportion of men seeking professional mental health care has risen over the past two decades, on average, men continue to attend fewer sessions of psychotherapy and are more likely to drop out of treatment prematurely compared to women. Men account for three-quarters of suicide deaths; furthermore, over half of the males who die by suicide have engaged with mental health care in the 12 months prior to their death. These findings highlight a need to equip mental health practitioners with skills to improve male clients’ engagement and mental health outcomes. This article reports the protocol for a randomized controlled trial of Men in Mind, a self-paced online training program purpose-built to advance the clinical competencies of practitioners who provide psychotherapy to male clients. Methods A randomized controlled trial with two parallel groups will be conducted. Participating practitioners will be randomly allocated, on a 1:1 basis, to the intervention group (Men in Mind training) or a waitlist control group. The primary outcome, efficacy of the training, will be evaluated by pre- to post-training (T1 to T2) changes in scores on the Engaging Men in Therapy Scale (EMITS) in the intervention group, relative to the control group. Discussion This trial will provide evidence of the efficacy of Men in Mind training, as an interim step towards adjusting content and delivery of the intervention to maximize the potential for sustaining and scaling. Trial registration: The trial was registered prospectively with the Australian New Zealand Clinical Trials Registry on 3rd December 2021 (ACTRN12621001669886).
Coordinating Heterogeneous Web Services through Handhelds using SyD?s Wrapper Framework
Creators: name: Padhye, Mohini
Publisher: name: Georgia State University
Year: 2004

description: Tying web services together to build large, distributed, collaborative applications has gathered noticeable momentum and a lot of research is being put in it. Along with
composition of the web services, coordination is one key aspect that has been considered
keenly.

Many frameworks, languages and protocols have been proposed for web service composition and coordination. With the advancement in wireless technology and rapid deployment of mobile services, collaborative application development for small devices using such composed web services finds a new research area. Much less work has been done in the area of web service coordination for mobile environment.

In this thesis, we propose a new distributed approach in service composition and coordination and show that our approach works well in an environment containing mobile heterogeneous devices. We discuss a novel approach of SyD (System on Devices)wrapper framework for dynamically creating and executing web bonds  among various heterogeneous web services. The wrapper is a lightweight SyD application object that encapsulates composition and coordination logic and provides higher level of coordination among bonded entities. The wrapper framework gives small devices full capability to run distributed collaborative applications that use heterogeneous web services. We have also developed and analyzed experiments to showcase the performance of SyD Wrapper Framework.
Tree Sprawl. Consolidation and Expansion of Open Vegetated Space: Projects in the Urban Territory of Merri Creek, Melbourne. Curated by Mauro Baracco
Creators: name: Baracco, Mauro
name: Macmillan, Luisa
Publisher: name: RMIT University
Year: 2024
Subjects: classificationCode: 330102
subject: Architectural design

description: No description available
Parallel Algorithm for Memory Efficient Pairwise and Multiple Genome Alignment in Distributed Environment
Creators: name: Ahmed, Nova
Publisher: name: Georgia State University
Year: 2004

description: The genome sequence alignment problems are very important ones from the computational biology perspective. These problems deal with large amount of data which is memory intensive as well as computation intensive.

In the literature, two separate algorithms have been studied and improved ? one is a Pairwise sequence alignment algorithm which aligns pairs of genome sequences with memory reduction and parallelism for the computation and the other one is the multiple sequence alignment algorithm that aligns multiple genome sequences and this algorithm is also parallelized efficiently so that the workload of the alignment program is well distributed.

The parallel applications can be launched on different environments where shared memory is very well suited for these kinds of applications. But shared memory environment has the limitation of memory usage as well as scalability also these machines are very costly. A better approach is to use the cluster of computers and the cluster environment can be further enhanced to a grid environment so that the scalability can be improved introducing multiple clusters. Here the grid environment is studied as well as the shared memory and cluster environment for the two applications. It can be stated that for carefully designed algorithms the grid environment is comparable for its performance to other distributed environments and it sometimes outperforms the others in terms of the limitations of resources the other distributed environments have.
RefNet  - Network of Reference Librarians: Join this network!
Creators: name: Pinto, Rosemeire
Publisher: name: Zenodo
Year: 2024
Subjects: RefNet
Reference Librarians

description: October 29st, 2024Strengthening Health Information Networks in Caribbean Virtual Health Library (VHL)

Coordination: Márcia Barretto, BIREME/PAHO/WHO

Opening remarks:Márcia Barretto, BIREME/PAHO/WHOVictoria Cruickshank-Taylor, Regional Coordinator of MedCarib Network

RefNet  - Network of Reference Librarians:Join this network!Rosemeire Pinto, BIREME/PAHO/WHO
A STUDY ON THE EFFECT OF TRAIN OVERLOAD IN THE SUSPENSION SYSTEM AND DESIGN PID CONTROLLER FOR SUPPRESSING THE EFFECT (CASE OF ADDIS ABABA LIGHT RAIL)
Creators: name: ELIANA BERHANU
Publisher: name: Zenodo
Year: 2020

description: A STUDY ON THE EFFECT OF TRAIN OVERLOAD IN 

THE SUSPENSION SYSTEM AND DESIGN PID 

CONTROLLER FOR SUPPRESSING THE EFFECT

(CASE OF ADDIS ABABA LIGHT RAIL)
Parallel SVM with Application to Protein Structure Prediction
Creators: name: Panaganti, Shilpa
Publisher: name: Georgia State University
Year: 2004

description: A learning task with thousands of training examples in Support Vector Machine (SVM) demands large amounts of memory and time requirements. SVMlight by Dr. Thorsten Joachims has been implemented in C using a fast optimizing algorithm for handling thousands of such support vectors. SVMlight solves the problem of classification, pattern recognition, regression and learning ranking function. The C code also provides methods for XiAlpha estimation of error rate and precision. Implementing these two methods leads to generalized performance of Support Vector Machine even for computation intensive text classification functions. SVMlight code allows users to define their own kernel functions. The SVMlight software employs an efficient algorithm and minimizes the cost, but it still takes considerable amount of time for computing thousands of support vectors and training examples. This time can be still reduced by parallelizing the code.

In our work we refined the SVMlight code by removing unnecessary iterations and rewriting it as cost efficient. Then we parallelized the code individually using two different types, OpenMP and POSIX Threads shared memory parallelism. The code is parallelized for these two methods on Intel?s C compiler for Linux 7.1 using hyper threading technology. The parallelized code is tested for protein structure prediction. Different types of Protein Sequences are tested on these methods by varying the number of training examples and support vectors. The time consumption and speedup are calculated for both OpenMP and Pthreads. Implementation of OpenMP and Pthreads together showed good increase in speedup.
Assessing the Economic Contribution of Ocean-Based Activities Using the Pacific Coast of British Columbia as a Case Study
Creators: name: Teh, Lydia C. L.
name: Cheung, William W. L.
name: Sumaila, Ussif Rashid
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2023

description: Global obligations to achieve sustainable oceans by 2030 require countries to commit to solutions that balance ocean use and protection. To do so necessitates baseline understanding of the ocean’s contribution to socio-economic well-being, which we do by measuring the economic activity of ocean-related sectors. Economic assessments tend to be data intensive and are typically reliant on professional economists, yet they are increasingly relevant to non-economists who engage in ocean management and communication, where they are integral in facilitating trade-off analysis of future ocean change. Thus, there is a need to make ocean economic assessment more accessible to nonspecialists. We fill this need by providing a pragmatic framework for conducting an economic assessment using British Columbia’s ocean sector as a case study. Our results show the impact of the province’s ocean sectors on four economic indicators and indicate that the ocean contributed almost $5 billion (or about 2%) to provincial gross domestic product (GDP) and generated about 106,120 jobs (over 4% of the province’s total) in 2015. Of these, the marine transport sector made the highest overall contribution followed by cruise lines, with GDP impacts of 66% and 13%, respectively. It should be noted that this estimated economic value is not representative of the full value of the ocean as it excludes oil and gas, research and education, and other activities that do not meet our criteria for inclusion, and it does not account for cultural and ecological values. Nonetheless the study highlights the substantial number of economic benefits generated by the blue economy. More significantly, the framework provides a simplified procedure for quantifying economic benefits, and can be applied by nonspecialists to perform rapid economic assessments in a variety of contexts.