cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Benralizumab: First Global Approval
Creators: name: Markham, Anthony
Publisher: name: Adis Journals
Year: 2018
Subjects: subject: Medicine
subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Compliance with Ethical Standards
Funding: The preparation of this review was not supported by any external funding.
Conflicts of interest: Anthony Markham is a salaried employee of Adis/Springer, is responsible for the article content and declares no relevant conflicts of interest.
Additional information about this Adis Drug Review can be found here.
Abstract
Kyowa Hakko Kirin, AstraZeneca and subsidiaries are developing benralizumab (Fasenraä) – a fully humanised anti-interleukin-5 receptor alpha chain (IL-5Ra) monoclonal antibody – as a treatment of severe eosinophilic asthma and chronic obstructive pulmonary disease (COPD). Eosinophilia is a characteristic of certain asthma and COPD phenotypes and depletion of eosinophils has demonstrated therapeutic benefit. Benralizumab was recently approved by the US FDA as add-on maintenance therapy for patients with severe asthma who have an eosinophilic phenotype. This article summarizes the milestones in the development of benralizumab leading to this first approval for the treatment of severe eosinophilic asthma. Access to the full article can be found here.
© Springer International Publishing AG, part of Springer Nature 2018
Elymus arenarius Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Elymus
Elymus arenarius

description: Elymus arenarius, spec. nov.
 1. Elymus foliis mucronato-pungentibus. It. scan. 336. Gen. nov. 1094.
 Secale spiculis geminatis. Fl. suec. 106.
 Triticum foliis acuminatis pungentibus. Roy. lugdb. 71.
 Gramen caninum maritimum, spica triticea, nostras. Raj. hist. 1256. Scheuch. gram.6.
 Habitat ad Europae litora marina in arena mobili. ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 83, DOI: 10.5281/zenodo.3931989
Detection of weak lensing by a cluster of galaxies at z=0.83
Creators: name: Luppino, G. A.
name: Kaiser, Nick
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the detection of weak gravitational lensing of faint, distant background galaxies by the rich, X-ray luminous cluster of galaxies MS1054-03 at z=0.83. This is the first measurement of weak lensing by a bona fide cluster at such a high redshift. We detect tangential shear at the 5% - 10% level over a range of radii 50'' < r < 250'' centered on the optical position of the cluster. Two-dimensional mass reconstruction using galaxies with 21.5 < I < 25.5 shows a strong peak which coincides with the peak of the smoothed cluster light distribution. Splitting this sample by magnitude (at I = 23.5) and color (at R-I = 0.7), we find that the brighter and redder subsamples are only very weakly distorted, indicating that the faint blue galaxies (FBG's), which dominate the shear signal, are relatively more distant. The derived cluster mass is quite sensitive to the N(z) for the FBG's. At one extreme, if all the FBG's are at z_s = 3, then the mass within a $0.5h^{-1}$Mpc aperture is $(5.9 \pm 1.24)\times 10^{14}$\h1 $M_\odot$, and the mass-to-light ratio is $M/L_V = 350 \pm 70 h$ in solar units. For $z_s = 1.5$ the derived mass is $\sim$70\% higher and $M/L \simeq 580 h$. If $N(z)$ follows the no evolution model (in shape) then $M/L \simeq 800h$, and if all the FBG's lie at $z_s\la 1$ the required $M/L$ exceeds $1600h$. These data provide clear evidence that large, dense mass concentrations existed at early epochs; that they can be weighed efficiently by weak lensing observations; and that most of the FBG's are at high redshift.
description: Submitted to ApJ, 15 pages (incl 8 figs, 3 of which are plates). Plate images not included, but are available from ftp://hubble.ifa.hawaii.edu/pub/ger/ms1054/ms1054_fig[1,3,5].ps.Z
Effects of Low Level Laser Therapy Vs Ultrasound Therapy in the Management of Active Trapezius Trigger Points.
Creators: name: Abraham Mammen, Abin
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420106
subject: Physiotherapy
classificationCode: 420701
subject: Biomechanics
classificationCode: 420702
subject: Exercise physiology
classificationCode: 420799
subject: Sports science and exercise not elsewhere classified

description: Effects of Low Level Laser Therapy Vs Ultrasound Therapy in the Management of Active Trapezius Trigger Points.
Anomalous Transverse Distribution of Pions as a signal for the production of DCC's
Creators: name: Cooper, F.
name: Kluger, Y.
name: Mottola, E.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We give evidence that the production of DCC's during a non-equilibrium phase transition can lead to an anomalous transverse distribution of secondary pions when compared to a more conventional boost invariant hydrodynamic flow in local thermal equilibrium. Our results pertain to the linear $σ$ model,treated in leading order in large-$N$, in a boost invariant approximation. We also show that the interpolating number density of the field theory calculation plays the role of a classical relativistic phase space number distribution in determining the momentum distribution of pions in the center of mass frame.
description: 10 pages, LaTex and 3 eps figures
Stochastic Approximation with Random Step Sizes and Urn Models with Random Replacement Matrices Having Finite Mean
Creators: name: Gangopadhyay, Ujan
name: Maulik, Krishanu
Publisher: name: arXiv
Year: 2017
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 62L20, 60F15, 60G42

description: Stochastic approximation algorithm is a useful technique which has been exploited successfully in probability theory and statistics for a long time. The step sizes used in stochastic approximation are generally taken to be deterministic and same is true for the drift. However, the specific application of urn models with random replacement matrices motivates us to consider stochastic approximation in a setup where both the step sizes and the drift are random, but the sequence is uniformly bounded. The problem becomes interesting when the negligibility conditions on the errors hold only in probability. We first prove a result on stochastic approximation in this setup, which is new in the literature. Then, as an application, we study urn models with random replacement matrices. In the urn model, the replacement matrices need neither be independent, nor identically distributed. We assume that the replacement matrices are only independent of the color drawn in the same round conditioned on the entire past. We relax the usual second moment assumption on the replacement matrices in the literature and require only first moment to be finite. We require the conditional expectation of the replacement matrix given the past to be close to an irreducible matrix, in an appropriate sense. We do not require any of the matrices to be balanced or nonrandom. We prove convergence of the proportion vector, the composition vector and the count vector in $L^1$, and hence in probability. It is to be noted that the related differential equation is of Lotka-Volterra type and can be analyzed directly.
description: This is a shortened version of the earlier one. This version contains only the convergence in probability under finite mean assumption. This version is accepted and going to appear in Annals of Applied Probability. The extended version of the remainder of the earlier copy will be submitted later
Cloud Statistics in Numerical Simulations of the ISM
Creators: name: Ballesteros-Paredes, J.
name: Vazquez-Semadeni, E.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present preliminary results on the energy budgets of clouds in two-dimensional numerical simulations of the interstellar medium. Using an automated cloud-identification algorithm, we calculate the gravitational, internal, kinetic and magnetic energies of the clouds. We find that, within a dispersion of roughly one order of magnitude, the gravitational energy in the clouds is balanced by the remaining energies. Furthermore, within the same dispersion, there appears to be equipartition between the kinetic and magnetic energies.
description: Gzipped, tarred Latex file (4 pages), 6 Postscript figures and one style file. Uses AAS macros. Gzipped Postscript file also available at ftp://kepler.astroscu.unam.mx/incoming/enro/papers/cloudstat.ps.gz
Wavelet analysis of Wave motion
Creators: name: Nicolleau, F. C. G. A.
name: Vassilicos, J. C.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In this paper high resolution wave probe records are examined using wavelet techniques with a view to determining the sources and relative contributions of capillary wave energy along representative wind wave forms. Wavelets enable computations of conditional spectra and turn out to be powerful tools for the study of the development and propagation of capillary waves. They also enable the detailed analyses of the relative contributions to the spectrum of the wave peaks and troughs.
title: Billet du maquisard du Vercors Michel Pérotin (Fressinat) à Gilberte Dumon, fiancée de son frère, le maquisard Yves Pérotin (Pothier), 5 août 1944, au crayon, signé Michel
Creators: name: Michel Pérotin (Fressinat)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: Maquis alpins, Deuxième guerre mondiale, correspondance des maquisards avec leurs familles

description: Billet du maquisard du Vercors Michel Pérotin (Fressinat) à Gilberte Dumon, fiancée de son frère, le maquisard Yves Pérotin (Pothier), 5 août 1944, au crayon, signé Michel
description: Source: GED Campus Condorcet Fonds Yves Pérotin CNRS-IHTP ARC 143 ; 2MAQ_45
Invariants of contact structures from open books
Creators: name: Etnyre, John B.
name: Ozbagci, Burak
Publisher: name: arXiv
Year: 2006
Subjects: subject: Geometric Topology (math.GT)
subject: Symplectic Geometry (math.SG)
subject: FOS: Mathematics
subject: 57R17

description: In this note we define three invariants of contact structures in terms of open books supporting the contact structures. These invariants are the support genus (which is the minimal genus of a page of a supporting open book for the contact structure), the binding number (which is the minimal number of binding components of a supporting open book for the contact structure with minimal genus pages) and the norm (which is minus the maximal Euler characteristic of a page of a supporting open book).
description: 18 pages, 11 figures
Elymus sibiricus Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Elymus
Elymus sibiricus

description: Elymus sibiricus, spec. nov.
 2. Elymus spica flaccido pendula, spiculis binatis. Hort. ups. 22. * Gen. nov. 1094.
 Triticum radice perenni, spiculis binis longissime aristatis, Gmel. sibir.1. p.123. t.28.
 Habitat in Sibiria . ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 83, DOI: 10.5281/zenodo.3931989
AirMettle: A Real-Time Smart Data Lake for Accelerated In-Place Analytics of Scientific Data
Creators: name: Stephens, Donpaul C.
Publisher: name: Zenodo
Year: 2023

description: In an era characterized by an exponential surge in data generation across scientific and industrial sectors, efficiently managing and processing extensive volumes of complex HDF5 and NetCDF4 data has become a pressing challenge. It is critical to understand that many analytics tasks demand processing only specific subsets of this data, often involving extractions, aggregations, or more sophisticated operations like re-scaling. Traditional retrieval of data for external processing is viable but not optimal due to speed and cost constraints, limiting researchers in the breadth of content they can effectively analyze.

AirMettle is spearheading an innovative approach to accelerate scientific data analysis. Our Real-Time Smart Data Lake (RT-SDL) seamlessly integrates massively parallel in-storage data processing within a robust, scalable, software-defined storage (SDS) framework. In this talk, we will elucidate how AirMettle empowers parallel in-place processing of NetCDF4 data, focusing on extractions and preliminary aggregations. We will also outline our ambitious endeavors to dynamically re-scale data and broaden our in-storage analytics capabilities to encompass a wider spectrum of HDF5 data.

Our work has garnered support from NSF and NOAA to date. We are actively collaborating on new initiatives with the HDF Group and the University of Alabama in Huntsville. We invite you to join us with your big data challenges; let’s explore how AirMettle can help make your data analysis lightning fast through intelligent storage solutions.
An Instrument For Investigation of the Cosmic Microwave Background Radiation at Intermediate Angular Scales
Creators: name: Wollack, E. J.
name: Devlin, M. J.
name: Jarosik, N.
name: Netterfield, C. B.
name: Page, L.
name: Wilkinson, D.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We describe an off-axis microwave telescope for observations of the anisotropy in the cosmic microwave background (CMB) radiation on angular scales between 0.5 deg and 3 deg. The receiver utilizes cryogenic high-electron-mobility transistor (HEMT) amplifiers and detects the total power in multiple 3 GHz wide channels. Both frequency and polarization information are recorded allowing discrimination between CMB radiation and potential foreground sources and allowing checks for systematic effects. The instrumental radiometric offset is small (~1 mK). Data are taken by rapidly sampling while sweeping the beam many beamwidths across the sky. After detection, a spatio-temporal filter is formed in software which optimizes the sensitivity in a multipole band in the presence of atmospheric fluctuations. Observations were made from Saskatoon, Saskatchewan (SK), Canada during the winter of 1993 with six channels between 27.6 and 34.0 GHz, in 1994 with twelve channels between 27.6 and 44.1 GHz, and in 1995 with six channels between 38.2 and 44.1 GHz. The performance of the instrument and assessment of the atmospheric noise at this site are discussed.
description: latex file is called inst.tex. 30 pages with 14 Postscript figures. Uses aas2pp4.sty (included). Submitted to ApJ
Pomalidomide: A Review in Relapsed and Refractory Multiple Myeloma
Creators: name: Hoy, Sheridan M.
Publisher: name: Adis Journals
Year: 2018
Subjects: Medicine

description: Compliance with Ethical Standards
Funding: The preparation of this review was not supported by any external funding.
Conflicts of interest: Sheridan Hoy is a salaried employee of Adis/Springer, is responsible for the article content and declares no relevant conflicts of interest.
Additional information about this Adis Drug Review can be found here.
Abstract
Pomalidomide (Imnovid®; Pomalyst®), an analogue of thalidomide, is an immunomodulatory agent, with several mechanisms of action (both direct and indirect) thought to be involved in its anti-myeloma activity. Oral pomalidomide is available in several countries for use in combination with low-dose dexamethasone in adults with relapsed and refractory multiple myeloma. In multinational, phase II or III studies in patients with refractory, or relapsed and refractory multiple myeloma who had received ≥ 2 prior treatment regimens (including ≥ 2 cycles of both lenalidomide and bortezomib), pomalidomide plus low-dose dexamethasone was associated with prolonged progression-free survival (PFS) and overall survival and an improved overall response rate. Pomalidomide plus low-dose dexamethasone had a manageable tolerability profile, with neutropenia, infections, anaemia and thrombocytopenia being the most frequently reported grade 3 or 4 treatment-emergent adverse events. In conclusion, pomalidomide plus low-dose dexamethasone extends the treatment options available for the management of relapsed and refractory multiple myeloma in a patient population that has very limited treatment options. Access to the full article can be found here.
© Springer International Publishing AG, part of Springer Nature 2017
Femtosecond valley polarization and topological resonances in transition metal dichalcogenides
Creators: name: Motlagh, S. Azar Oliaei
name: Wu, Jhih-Sheng
name: Apalkov, Vadym
name: Stockman, Mark I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We theoretically introduce the fundamentally fastest induction of a significant population and valley polarization in a monolayer of a transition metal dichalcogenide (i.e., $\mathrm{MoS_2}$ and $\mathrm{WS_2}$). This may be extended to other two-dimensional materials with the same symmetry. This valley polarization can be written and read-out by a pulse consisting of just a single optical oscillation with a duration of a few femtoseconds and an amplitude of $\sim0.2~\mathrm V/\mathrmÅ$. Under these conditions, we predict a new effect of {\em topological resonance}, which is due to Bloch motion of electrons in the reciprocal space where electron population textures are formed defined by non-Abelian Berry curvature. The predicted phenomena can be applied for information storage and processing in PHz-band optoelectronics.
description: 9 pages, 7 figures
Elymus canadensis Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Elymus
Elymus canadensis

description: Elymus canadensis, spec. nov.
 3. Elymus spica flaccido-pendula, spiculis inferioribus ternatis; superioribus binatis. Gen. nov. 1094.
 Gramen secalinum majus altissimum virginianum. Moris. hist.3. p.180. s.8. t.10. f.2. Raj. suppl. 599.
 Habitat in Canada . Kalm. ♃
  Convenit in plurimis cum E.Sibirico , a quo tamen differt 1.Spiculis villosis, nec nudis. 2. involucris in aristam exeuntibus longioribus ipsa spicula; demtis aristis; at in sibirica involucrum minus subulatum, sed fere lanceolatum in aristam definens, quae longe brevior sua spicula. 3. Spicae inferne ternae, quum Sibirica semper duas obtineat. 4. Spiculae , dum florent, dehiscunt a scapo patulo, in sibirica vero spiculae approximatae sunt scapo. Variat haec spicis incurvis & pendulis. 84 Aristae corollinae cum maturescit fructus patenti-reflexae sunt contra ac in Sibirica.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 83, DOI: 10.5281/zenodo.3931989
A Measurement of the Angular Power Spectrum of the Anisotropy in the Cosmic Microwave Background
Creators: name: Netterfield, C. B.
name: Devlin, M. J.
name: Jarosik, N.
name: Page, L.
name: Wollack, E. J.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report on a measurement of the angular power spectrum of the anisotropy in the Cosmic Microwave Background. The anisotropy is measured in 23 different multipole bands from l=54 (~3 deg) to l=404 (~0.45 deg) and in 6 frequency bands from 26 GHz to 46 GHz over three observing seasons. The measurements are consistent from year to year. The frequency spectral index of the fluctuations (measured at low l) is consistent with that of the CMB and inconsistent with either dust or Galactic free-free emission. Furthermore, the observations of the MSAM1-92 experiment (Cheng et al. 1994) are repeated and confirmed. The angular spectrum shows a distinct rise from dT_l = \sqrt{l(2l+1)/4pi} = 49(+8,-5) \uK at l=87 to dT_l=85(+10,-8) uK at l = 237. These values do not include an overall +/-14\% (1sigma) calibration uncertainty. The analysis and possible systematic errors are discussed.
description: latex file is called spect.tex. 25 pages with 11 Postscript figures. Uses aas2pp4.sty (included). Submitted to ApJ
Single-atom-resolved probing of lattice gases in momentum space
Creators: name: Cayla, Hugo
name: Carcy, Cécile
name: Bouton, Quentin
name: Chang, Rockson
name: Carleo, Giuseppe
name: Mancini, Marco
name: Clément, David
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Measuring the full distribution of individual particles is of fundamental importance to characterize many-body quantum systems through correlation functions at any order. Here we demonstrate the possibility to reconstruct the momentum-space distribution of three-dimensional interacting lattice gases atom-by-atom. This is achieved by detecting individual metastable Helium atoms in the far-field regime of expansion, when released from an optical lattice. We benchmark our technique with Quantum Monte-Carlo calculations, demonstrating the ability to resolve momentum distributions of superfluids occupying $10^5$ lattice sites. It permits a direct measure of the condensed fraction across phase transitions, as we illustrate on the superfluid-to-normal transition. Our single-atom-resolved approach opens a new route to investigate interacting lattice gases through momentum correlations.
description: 7 pages, 5 figures
Scale dependence of quark mass matrices in models with flavor symmetries
Creators: name: Aguilar-Saavedra, J. A.
name: Masip, M.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Numerical correlations between fermion masses and mixings could indicate the presence of a flavor symmetry at high energies. In general, the search for these correlations using low-energy data requires an estimate of leading-log radiative corrections. We present a complete analysis of the evolution between the electroweak and the grand unification scales of quark mass parameters in minimal supersymmetric models. We take $M_t=180$ GeV and consider all possible values of $\tan β$. We also analize the possibility that the {\it top} and/or the {\it bottom} Yukawa couplings result from an intermediate quasifixed point (QFP) of the equations. We show that the quark mixings of the third family do {\it not} have a QFP behaviour (in contrast to the masses, the renormalization of all the mixings is linear), and we evaluate the low-energy value of $V_{ub}$ which corresponds to $V_{ub}(M_X)=0$. Then we focus on the renormalization-group corrections to {\it (i)} typical relations obtained in models with flavor symmetries at the unification scale and {\it (ii)} a superstring-motivated pattern of quark mass matrices. We show that in most of the models the numerical prediction for $V_{ub}$ can be {\it corrected} in both directions (by varying $\tanβ$) due to {\it top} or {\it bottom} radiative corrections.
description: LaTeX, 14 pages, 4 figures, 3 tables. Uses epsf.sty. PostScript available at http://deneb.ugr.es/papers/ugft60.ps.gz Plain LaTeX, Positions of the figures corrected again
Elymus virginicus Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Elymus
Elymus virginicus

description: Elymus virginicus, spec. nov.
 4. Elymus spica erecta, spicula involucro longiore. Hort. ups.22.
 Hordeum flosculis omnibus hermaphroditis, involucris flosculos crassitie & longitudine superantibus. Gron. virg.13.
 Habitat in Virginia . ♃
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 84, DOI: 10.5281/zenodo.3931989
The observed distribution function of peculiar velocities of galaxies
Creators: name: Raychaudhury, Somak
name: Saslaw, William C.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We give the first determination of the observed peculiar velocity distribution function for a representative sample of galaxies (within 50 Mpc (H=100) of the Local Group), which includes a wide range of clustering properties. We explore in detail the effects of uncertainties in sampling and in distance measures on the estimated distribution function. The observed distribution function is consistent with an earlier prediction of gravitational clustering, over the entire range of peculiar velocities, from field galaxies to rich clusters, on scales up to 50 Mpc (H=100). In the simplest consistent model, most of the inhomogeneous mass of the Universe is in galaxies or their halos. We estimate the ``Mach Number'' for the bulk flow within 50 Mpc (H=100) from us to be approximately 0.8, which includes the effect of high-dispersion galaxies in clusters.
description: 28 pages, gzipped postscript file, including 11 figures and 2 tables; To appear in the Astrophysical Journal, March 1996
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Cart. 189 (11 H 74), 316 folios, f. 0064r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0064r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0064r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
High Energy Neutrino Production by Cosmic Ray Interactions in the Sun
Creators: name: Ingelman, G.
name: Thunman, M.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The flux of neutrinos originating from cosmic ray interactions with matter in the Sun has been calculated based on Monte Carlo models for high energy particle interactions. The resulting flux at the Earth (within the Sun's solid angle) is higher than the corresponding one from cosmic ray interactions with the Earth atmosphere. The smallness of the absolute rate, however, precludes it as a practical `standard candle' for neutrino telescopes and limits neutrino oscillation searches. On the other hand, it facilitates dark matter searches based on neutrinos from neutralino annihilation in the Sun.
description: 14 pages, also available at http://www3.tsl.uu.se/thep/papers/
Lettre de George Charles à Jean-François Séguier, 1776-08-20
Creators: name: Charles, George
name: Charles, George
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Histoire naturelle (général)

description: [Répondu le 9 décembre 1776] Old Bond Street, London le 20 août 1776.

Monsieur,

La lettre du 3e avril dernièrement passé dont vous avez bien voulu m’honorer fut présentée à My Lord Bute en son temps et j’eus conséquemment ses ordres de vous en remercier et de vous faire connaître combien il chérissait votre précieuse amitié, bien sensible à l’état chancelant de votre santé, laquelle a tant souffert du rhumatisme. Voici, entre autres choses, que j’eus l’honneur de vous dire de la part de My Lord Bute le 3 du mois (de mai) suivant et en outre qu’il serait bien aise d’avoir des semences des plantes personnelles du sud (any seeds of the Southern perennial plants). Je vous ai marqué que l’envoi desdites semences devait se faire à moi, adresser les donc, je vous prie, à moi in Old Bond street, London… à l’égard de ce que vous voulez savoir au sujet de l’Herbarium Britannicum (The English Plants), My Lord m’a chargé de vous dire que Monsieur Hill s’était proposé d’en faire 4 volumes mais qu’il s’arrêta au 2°. Ainsi, vous en avez, Monsieur, la première partie…. Du Vegetable System. Les volumes qui vous manquent sont le 22e, le 23e et le 24e. Il y a plus de trois mois qu’ils sont prêts à partir, l’agent en étant chargé exprès, mais ce qui est bien extraordinaire qu’il ne s’est présenté aucune occasion pour le port de Marseille depuis ce temps-là. My Lord a donné ordre d’y mettre le 25e volume, lequel est le dernier de tout l’ouvrage, de la main de Hill…. Soyez persuadé, Monsieur, que le tout vous sera expédié par la première occasion pour Marseille avec les connoissements pour M. Birkbeck.

[Séguier à Nîmes]

[fol. 117v] Monsieur Crofts vous aura informé sans doute que je me suis acquitté de vos ordres chez lui.
N’ayant été honoré de vos nouvelles depuis la susdite lettre du 3e avril, me fait douter si ma réponse vous est parvenue. Ayez la bonté, mon respectable ami, de me faire savoir, afin de mettre ordre à ce qui est nécessaire.
J’ai le plaisir de vous assurer, Monsieur, que la santé de notre respectable ami le lord Bute se soutient à merveille et l’honneur de vous assurer de son sincère souvenir. Je vous prie d’être persuadé de l’attachement respectueux avec lequel je suis, Monsieur,

 Votre très humble et très obéissant serviteur

 G. Charles

[fol. 118v] A Monsieur

Monsieur Séguier
A Nîmes

La France
description: Source: [établissement de conservation] Nîmes, Bibliothèque Carré d'Art [cote] ms. 249, fol. 117-118
Afatinib in advanced NSCLC: a profile of its use
Creators: name: Deeks, Emma D.
name: Keating, Gillian M.
Publisher: name: Adis Journals
Year: 2018
Subjects: Medicine
Cancer

description: Compliance with ethical standards
Funding: This article was made open access (CC-BY-NC) following publication, with funding for this provided by Boehringer Ingelheim Pharmaceuticals, Inc.
Conflict of interest: E. D. Deeks and G. M. Keating are employees of Adis/Springer, are responsible for the article content and declare no conflicts of interest.
Additional information about this Adis Drug Review can be found here.
Abstract
Afatinib [Giotrif® (EU); Gilotrif® (USA)] is an orally administered, irreversible inhibitor of the ErbB family of tyrosine kinases that provides an important first-line treatment option for advanced non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) mutations (i.e. EGFRactMUT+), and an additional treatment option for squamous NSCLC that has progressed following first-line platinum-based chemotherapy. Relative to gefitinib in the first-line treatment of EGFRactMUT+ advanced lung adenocarcinoma, afatinib prolonged progression-free survival (PFS) and time to treatment failure (TTF), but not overall survival (OS). Afatinib also prolonged PFS, but not OS, versus cisplatin-based chemotherapy in this setting; however, afatinib improved OS versus chemotherapy in the subgroup of patients with deletions in exon 19. As a second-line treatment for advanced squamous NSCLC, afatinib prolonged PFS and OS compared with erlotinib, regardless of EGFR mutation status. Afatinib had a predictable and manageable tolerability profile. Access to the full article can be found here.
© Springer International Publishing AG, part of Springer Nature 2018
Elymus caput-medusae Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Elymus
Elymus caput-Medusae

description: Elymus caput-medusae, spec. nov.
5. Elymus spiculis unifloris involucris setaceis patentissimis.
 Elymus involucris reflexo-patentibus. Gen. nov. 1094.
 Avena lusitanica spicata, caput medusae referens. Moris. hist.3. p.210. Raj. suppl. 611.
 Gramen hordeaceum, spica aristis longissimis circumvallata. Scheuch. gram. 20.?
 Habitat in Lusitaniae , Hispaniae maritimis.
 Entire species Hystriae from author's Addenda.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 84, DOI: 10.5281/zenodo.3931989
title: ADCO, Ordre cistercien : comptes (1403-1423) (11 H 1161), f. 00258
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: comptes
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes (1403-1423), Archives départementales de la Côte-d'Or, (11 H 1161), f. 00258, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
Signals for Intrinsic Charm in High Energy Interactions
Creators: name: Ingelman, G.
name: Thunman, M.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The prospects to test the hypothesis of intrinsic charm quarks in the proton are investigated. We consider how this component can be directly or indirectly probed in deep inelastic scattering at HERA and in fixed target experiments and find that an overlooked signal might be present in existing NMC data. Applying the intrinsic charm model to hadron collisions we compare the resulting charm production cross-sections with those based on standard perturbative QCD and available data. Extrapolating to higher energies we obtain predictions for charm production at the Tevatron and LHC.
description: 18 pages, also available at http://www3.tsl.uu.se/thep/papers/
Elymus hystrix Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Elymus
Elymus hystrix

description: Elymus hystrix, spec. nov.
6. Elymus spiculis involcro destitutis.
 Gramen avenaceum, locustis aristatis, paniculis echinum referentibus. Gronov.
 Habitat in - - - -
 Spica composita ex Spiculis duabus ad singulum dentem. Spiculae quadriflorae; aristis longis. Involucra nulla, sed horum loco Calli duo.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 84, DOI: 10.5281/zenodo.3931989
Integrative analysis reveals disrupted pathways regulated by microRNAs in cancer
Creators: name: Wilk, Gary
name: Braun, Rosemary
Publisher: name: arXiv
Year: 2017
Subjects: subject: Genomics (q-bio.GN)
subject: FOS: Biological sciences

description: MicroRNAs (miRNAs) are small endogenous regulatory molecules that modulate gene expression post-transcriptionally. Although differential expression of miRNAs have been implicated in many diseases (including cancers), the underlying mechanisms of action remain unclear. Because each miRNA can target multiple genes, miRNAs may potentially have functional implications for the overall behavior of entire pathways. Here we investigate the functional consequences of miRNA dysregulation through an integrative analysis of miRNA and mRNA expression data using a novel approach that incorporates pathway information a priori. By searching for miRNA-pathway associations that differ between healthy and tumor tissue, we identify specific relationships at the systems-level which are disrupted in cancer. Our approach is motivated by the hypothesis that if a miRNA and pathway are associated, then the expression of the miRNA and the collective behavior of the genes in a pathway will be correlated. As such, we first obtain an expression-based summary of pathway activity using Isomap, a dimension reduction method which can articulate nonlinear structure in high-dimensional data. We then search for miRNAs that exhibit differential correlations with the pathway summary between phenotypes as a means of finding aberrant miRNA-pathway coregulation in tumors. We apply our method to cancer data using gene and miRNA expression datasets from The Cancer Genome Atlas (TCGA) and compare ${\sim}10^5$ miRNA-pathway relationships between healthy and tumor samples from four tissues (breast, prostate, lung, and liver). Many of the flagged pairs we identify have a biological basis for disruption in cancer.
Resumming Phase Space Logarithms in Inclusive Semileptonic $B$ Decays
Creators: name: Bauer, Christian
name: Falk, Adam F.
name: Luke, Michael
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study logarithms of the form $\ln(m_q/m_b)$ which arise in the inclusive semileptonic decay of a bottom quark to a quark of mass $m_q$. We use the renormalization group to resum the leading radiative corrections to these terms, of the form $m_q^2α_s^n\ln^n(m_q/m_b)$, $m_q^3α_s^{n+1}\ln^n(m_q/m_b)$ and $m_q^4α_s^n\ln^{n+1}(m_q/m_b)$. The first two resummations are trivial, while the latter involves a non-trivial mixing of four-fermi operators in the $1/m_b$ expansion. We illustrate this technique in a toy model in which the semileptonic decay is mediated by a vector interaction, before treating the more complicated case of left-handed decay.
description: 18 pages, REVTeX, 8 EPS figures embedded. Final version, to appear in Physical Review D; one reference has been added
Perfect tight quantum teleportation without a shared reference frame
Creators: name: Verdon, Dominic
name: Vicary, Jamie
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a new scheme for teleporting a quantum state between two parties whose local reference frames are misaligned by the action of a finite symmetry group. Unlike other proposals, our scheme requires the same amount of classical communication and entangled resources as conventional teleportation, does not reveal any reference frame information, and is robust against changes in reference frame alignment while the protocol is underway. The mathematical foundation of our scheme is a unitary error basis which is permuted up to a phase by the conjugation action of the group. We completely classify such unitary error bases for qubits, exhibit constructions in higher dimension, and provide a method for proving nonexistence in some cases.
description: Clarified exposition and added extra figures. 24 pages, 5 figures
Secale cereale Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Secale
Secale cereale

description: Secale cereale, spec. nov.
 Habitat - - - - ☉
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 84, DOI: 10.5281/zenodo.3931989
Observations of Cygnus X-1 in the MeV band by the INTEGRAL imager
Creators: name: Walter, R.
name: Xu, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The spectrum of the MeV tail detected in the black-hole candidate Cygnus X-1 remains controversial as it appeared much harder when observed with the INTEGRAL Imager IBIS than with the INTEGRAL spectrometer SPI or CGRO. We present an independent analysis of the spectra of Cygnus X-1 observed by IBIS in the hard and soft states. We developed a new analysis software for the PICsIT detector layer and for the Compton mode data of the IBIS instrument and calibrated the idiosyncrasies of the PICsIT front-end electronics. The spectra of Cygnus X-1 obtained for the hard and soft states with the INTEGRAL imager IBIS are compatible with those obtained with the INTEGRAL spectrometer SPI, with CGRO, and with the models that attribute the MeV hard tail either to hybrid thermal/non-thermal Comptonisation or to synchrotron emission.
description: 6 pages, 7 figures
MHD Turbulence, Cloud Formation and Star Formation in the ISM
Creators: name: Vazquez-Semadeni, E.
name: Passot, T.
name: Pouquet, A.
Publisher: name: arXiv
Year: 1996
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We discuss the role of turbulence in cloud and star formation, as observed in numerical simulations of the interstellar medium. Turbulent compression at the interfaces of colliding gas streams is responsible for the formation of intermediate ($\simlt 100$ pc) and small clouds (a few tens of pc), although the smallest clouds can also form from fragmentation of expanding shells around stellar heating centers. The largest cloud complexes (several hundred pc) seem to form by slow, gravitational instability-driven merging of individual clouds, which can actually be described as a large-scale tendency towards homogenization of the flow due to gravity rather than cloud collisions. These mechanisms operate as well in the presence of a magnetic field and rotation, although slight variations on the compressibility and cloud morphology are present which depend on the strength and topology of the field. In summary, the role of turbulence in the life-cycle of clouds appears to be twofold: small-scale modes contribute to cloud support, while large-scale modes can both form or disrupt clouds.
description: Gzipped, tarred Latex file (7 pages), and style file. Uses AAS macros. Gzipped Postscript file with 9 figures available at ftp://kepler.astroscu.unam.mx/incoming/enro/papers/mhdcfsf.ps.gz
Extreme Quantum Advantage for Rare-Event Sampling
Creators: name: Aghamohammadi, C.
name: Loomis, S. P.
name: Mahoney, J. R.
name: Crutchfield, J. P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computational Complexity (cs.CC)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We introduce a quantum algorithm for efficient biased sampling of the rare events generated by classical memoryful stochastic processes. We show that this quantum algorithm gives an extreme advantage over known classical biased sampling algorithms in terms of the memory resources required. The quantum memory advantage ranges from polynomial to exponential and when sampling the rare equilibrium configurations of spin systems the quantum advantage diverges.
description: 11 pages, 9 figures; http://csc.ucdavis.edu/~cmg/compmech/pubs/eqafbs.htm
The Ringel dual of the Auslander-Dlab-Ringel algebra
Creators: name: Conde, Teresa
name: Erdmann, Karin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: The ADR algebra $R_A$ of a finite-dimensional algebra $A$ is a quasihereditary algebra. In this paper we study the Ringel dual $\mathcal{R}(R_A)$ of $R_A$. We prove that $\mathcal{R}(R_A)$ can be identified with $(R_{A^{op}})^{op}$, under certain 'minimal' regularity conditions for $A$. We also give necessary and sufficient conditions for the ADR algebra to be Ringel selfdual.
description: 25 pages
Secale cereale var. hybernum Linnaeus, 1753, var. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Secale
Secale cereale
Secale cereale var. hybernum

description: Secale cereale var. hybernum, var. nov.
 1. Secale glumarum ciliis scabris. Hort. ups. 22.
 Secale hybernum vel majus. Bauh. pin. 22. theatr. 425.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 84, DOI: 10.5281/zenodo.3931989
Angular Lens
Creators: name: Sahu, Rishabh
name: Chaudhary, Swati
name: Khare, Kedar
name: Bhattacharya, Mishkatul
name: Wanare, Harshawardhan
name: Jha, Anand Kumar
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We propose a single phase-only optical element that transforms different orbital angular momentum (OAM) modes into localized spots at separated angular positions on a transverse plane. We refer to this element as an angular lens since it separates out OAM modes in a manner analogous to how a converging lens separates out transverse wave-vector modes at the focal plane. We also simulate the proposed angular lens using a spatial light modulator and experimentally demonstrate its working. Our work can have important implications for OAM-based classical and quantum communication applications.
description: 5 pages, 5 figures
Secale cereale var. vernum Linnaeus, 1753, var. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Secale
Secale cereale
Secale cereale var. vernum

description: Secale cereale var. vernum, var. nov.
 β. Secale vernum s. minus. Bauh. pin. 23.
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 84, DOI: 10.5281/zenodo.3931989