cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Prompt-Guided Image-Adaptive Neural Implicit Lookup Tables for Interpretable Image Enhancement
Creators: name: Kosugi, Satoshi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper, we delve into the concept of interpretable image enhancement, a technique that enhances image quality by adjusting filter parameters with easily understandable names such as "Exposure" and "Contrast". Unlike using predefined image editing filters, our framework utilizes learnable filters that acquire interpretable names through training. Our contribution is two-fold. Firstly, we introduce a novel filter architecture called an image-adaptive neural implicit lookup table, which uses a multilayer perceptron to implicitly define the transformation from input feature space to output color space. By incorporating image-adaptive parameters directly into the input features, we achieve highly expressive filters. Secondly, we introduce a prompt guidance loss to assign interpretable names to each filter. We evaluate visual impressions of enhancement results, such as exposure and contrast, using a vision and language model along with guiding prompts. We define a constraint to ensure that each filter affects only the targeted visual impression without influencing other attributes, which allows us to obtain the desired filter effects. Experimental results show that our method outperforms existing predefined filter-based methods, thanks to the filters optimized to predict target results. Our source code is available at https://github.com/satoshi-kosugi/PG-IA-NILUT.
description: Accepted to ACM Multimedia 2024
HIGH PROLIFERATION AND NORMAL APOPTOSIS ARE THE KINETIC HALLMARKS OF CUTANEOUS MERKEL CELL CARCINOMAS
Creators: name: Diaz-Cano, Salvador J.
name: A Blanes
name: I Hierro
name: J Rubio
name: A Martinez
name: JJ Sanchez-Carrillo
name: A Matilla
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Cancer

description: Background: Merkel cell carcinomas (MCCs) are unusual cutaneous neoplasms that reveal both epithelial and neuroendocrine differentiation. No detailed analysis of cell kinetics (proliferation and apoptosis) by topographic compartments is available to date. Methods: All MCCs were required to express at least two epithelial and two neural markers from a panel including cytokeratin cocktail AEl -AE3, cytokeratin 20, synaptophysin, chromogranin A, neurofilament protein, and neuron-specific enolase, along with consistent ultrastructural findings. We selected 19 MCCs to evaluate mitotic figure (MF) counting, Ki-67 index, and apoptosis index based on the in situ end labeling (ISEL) of fragmented DNA using digoxigenin-labeled dUTP and Escherichia coli DNA polymerase I (Klenow fragment). At least 50 high-power fields were screened per topographic compartment (superficial or papillary dermis, and deep or reticular dermis), recording average and standard deviation for each variable. Variables were statistically compared in each tumor compartment using analysis of variance and Student t-test (significant if P<0.05.
Results: MCCs revealed high cell density (over 425 cell/HPF) and no statistical differences for theproliferation-markers by topographic compartments. Apoptosis showed lower values in the deep compartment, but only significant for the standard deviation of ISEL index (P=0.0074).
Conclusions: Homogeneously distributed high proliferation defines MCCs. Apoptosis follows the distribution pattern of proliferation in superficial compartments, whereas in deep compartments the apoptosis distribution is less variable and independent from proliferation.
Is Love Equal Before the Law? Same-Sex Relationships in the Serbian Legal Framework
Creators: name: Mihajlović, Aleksandar
name: Muminović, Emina
name: Vasilić, Veronika
Publisher: name: Civil Rights Defenders
Year: 2021
Subjects: same-sex relationships, legal recognition, Serbia

description: The purpose of this policy paper is to advocate for the improvement of the position of the LGBTIQ community in Serbia through the legal recognition of same-sex relationships, by approaching decisionmakers, precisely, the Serbian government, the newly established Ministry of Human and Minority Rights and Social Dialogue and other relevant stakeholders, as well as the Delegationof the European Union to the Republic of Serbia. Only in collaboration with the relevant authorities, the Republic of Serbia will fully follow its international human rights obligations and ensure legal status to same-sex couples.

The policy paper also provides a detailed list of recommendations for Serbian authorities. The successful implementation of recommendations would improve the protection of the LGBTIQ community and tackle discrimination based on sexual orientation, which is still very persistent in the country. We separated recommendations into the three groups, based on the three branches of power (the executive, legislative and judiciary), which will have the authority to participate in the process of drafting, passing or implementing the law on same-sex relationships. CSOs in Serbia are recognized as a very important partner in these processes which will work with each of the abovementioned stakeholders. The accent is on the Ministry of Human and Minority Rights and Social Dialogue which should propose a draft of the law, as well as other relevant ministries which should propose changes of other relevant laws, thus ensuring the full implementation of the law on the legal recognition of same-sex relationships. The National Assembly has been recognized as very important for the process of debating and holding public hearings through its relevant committees, as well as the judiciary, which will be responsible for resolving different types of disputes in civil or criminal cases potentially related to same-sex relationships.
Additional file 1 of Gaps and challenges: WHO treatment recommendations for tobacco cessation and management of substance use disorders in people with severe mental illness
Creators: name: Das-Munshi, Jayati
name: Semrau, Maya
name: Barbui, Corrado
name: Chowdhary, Neerja
name: Gronholm, Petra C.
name: Kolappa, Kavitha
name: Krupchanka, Dzmitry
name: Dua, Tarun
name: Thornicroft, Graham
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Search terms. Search terms for each PICO question.
Curvelet imaging and processing : adaptive multiple elimination
Creators: name: Herrmann, Felix J.
name: Verschuur, Eric
Publisher: name: Canadian Society of Exploration Geophysicists
Year: 2008

description: Predictive multiple suppression methods consist of two main steps: a prediction step, in which multiples are predicted from the seismic data, and a subtraction step, in which the predicted multiples are matched with the true multiples in the data. The last step appears crucial in practice: an incorrect adaptive subtraction method will cause multiples to be sub-optimally subtracted or primaries being distorted, or both. Therefore, we propose a new domain for separation of primaries and multiples via the Curvelet transform. This transform maps the data into almost orthogonal localized events with a directional and spatial-temporal component. The multiples are suppressed by thresholding the input data at those Curvelet components where the predicted multiples have large amplitudes. In this way the more traditional filtering of predicted multiples to fit the input data is avoided. An initial field data example shows a considerable improvement in multiple suppression.
Dietary Factors and the Causal Relationship with Benign Prostatic Hyperplasia: A Two-Sample Mendelian Randomization Study
Creators: name: Liu, Handong
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420605
subject: Preventative health care
classificationCode: 310501
subject: Anthropological genetics

description: Objective: This study aims to explore the causal relationship between dietary factors and benign prostatic hyperplasia (BPH) using two-sample Mendelian randomization (MR) analysis. Methods: Exposure and outcome variables were extracted from large-scale genome-wide association studies (GWAS) summary data, employing the inverse variance-weighted (IVW) method as the primary MR analysis approach, supplemented by MR-Egger, weighted median, simple mode, and weighted mode methods. Heterogeneity and pleiotropy analyses were conducted, and the MR-PRESSO method was utilized to remove outliers and assess horizontal pleiotropy. Subsequently, MR analysis was repeated post-outlier removal to verify robustness. Results: Genetic predictions indicated that lamb/mutton intake (IVW: OR = 3.576, 95% CI = 0.430-2.118, P = 0.003) and alcohol intake frequency (IVW: OR = 1.297, 95% CI = 0.047-0.473, P = 0.017) were positively associated with increased BPH risk, while fresh fruit intake (IVW: OR = 0.430, 95% CI = -1.561 to -0.127, P = 0.021) was inversely associated with BPH risk. Other dietary factors did not show statistically significant associations (P > 0.05). Conclusion: MR results demonstrate that lamb, alcohol, and fresh fruit intake are causally associated with BPH, with no significant associations for other dietary factors.
GENETIC EVOLUTION OF NEURAL CREST DERIVATIVES IN MULTIPLE ENDOCRINE NEOPLASIA 2A. DIFFERENTIAL PATTERNS FOR C-CELL AND ADRENAL MEDULLARY HYPERPLASIAS
Creators: name: Diaz-Cano, Salvador J.
name: A Blanes
name: M De Miguel
name: R Tashjian
name: HJ Wolfe
Publisher: name: figshare
Year: 2012
Subjects: subject: Medicine
subject: Molecular Biology
subject: Cancer
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences

description: Background: C-cell hyperplasias (CCH) and adrenal medullary hyperplasias (AMH) have been reported multifocal and monoclonal in multiple endocrine neoplasia2A, but the genetic evolution of those lesions remains unknown.
Methods: We selected 10 females with bilateral CCH and 11 with AMH from known MEN-2A kindred (RET point mutation in codon 634). DNA was extracted from microdissected samples of 22 CCH foci (one per lobe) and from 34 AMH nodules. The samples were used for HUMARA clonality test (with Hhal digestion) and microsatellite pattern analysis of TP53, RB1, WT1, and NF1 by PCR denaturing gradient gel electrophoresis. Sample clonality and microsatellite patterns were compared !n each patient, including only informative cases in the final analysis.
Results: CCH foci (I6118 from 9 informative patients) and AMH nodules (27/30 from 9 informative patients) revealed the same androgen receptor allele inactivated in each patient. The microsatellite analysis showed loss of heterozygosity (LOH) for TP53 (6110, 60%), RB1 (4/7, 57%) in CCH, all with concordant LOH pattern in each lobe. In contrast, AMH revealed heterogeneous and lower incidence of LOH for TP53 (3110, 30%), RB1 (118, 13%), WT1 (319, 33%), and NF1 (316, 50%), with discordant microsatellite pattern in 67% of cases.
Conclusions: Both CCH and AMH are essentially monoclonal lesions in MEN-PA and reveal divergent genetic evolution. Early TP53 and RE1 genetic alterations (concordant in both lobes) characterize CCH and support the neoplastic nature of this lesion. AMH is heterogeneous and shows low incidence of microsatellite abnormalities.with discordant patterns involving NF1 locus; these genetic findings are not consistent with a fully established neoplasm.
GENETIC HETEROGENEITY BY TOPOGRAPHIC COMPARTMENTS IN PHEOCHROMOCYTOMAS SUGGEST A CONVERGENT CELL SELECTION IN THE PERIPHERAL AREA
Creators: name: Diaz-Cano, Salvador J.
name: A Blanes
name: M De Miguel
name: R Tashjian
name: H Galera
name: HJ Wolfe
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Molecular Biology
Cancer
Cell Biology

description: Background: Adrenal pheochromocytomas have been extensively studied at the molecular level, but no information is available on their molecular profile by topographic compartments
Methods: Microdissected samples from the peripheral and internal zones of 73 pheochromocytomas (49 sporadic, 24 associated to MEN2A) were selected for loss of heterozygosity (LOH) and single nucleotide polymorphism (SNP) analyses. Five polymorphic DNA regions from TP53, RB1, WT1, and NF1 were systematically studied by polymerase chain reaction-denaturing gradient gel electrophoresis. Statistical differences between tumor compartments were evaluated using Fisher's exact test. Pheochromocytomas were classified malignant (8 sporadic tumors with distant metastases), locally invasive (15 sporadic tumors showing retroperitoneal infiltration only), and benign (all remaining tumors).
Results: LOH/SNP involved TP53 in 20/67 informative cases (29.9%), RB1 in 11/53 informative cases (20.8%), WT1 in 16/60 informative cases (26.7%), and NF1 in 16/40 informative cases (40.0%). Peripheral compartment revealed more genetic alterations in 17 pheochromocytomas (23.3%): 6 benign, 5 locally invasive (NF1 locus, p<0.00001), and 6 malignant (TP53 locus, p=0.00933). MEN-2A pheochromocytomas revealed higher proportion of NF1 locus abnormalities.
Conclusions: We conclude that convergent selection at the peripheral compartment of pheochromocytomas determines the accumulation of microsatellite lesions and intratumor heterogeneity (TP53 and NF1 loci) that eventually results in multistep tumorigenesis.
Global solution to the drift-diffusion-Poisson system for semiconductors with nonlinear recombination-generation rate
Creators: name: Wu, Hao
name: Jiang, Jie
Publisher: name: arXiv
Year: 2011
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: In this paper, we study the Cauchy problem of a time-dependent drift-diffusion-Poisson system for semiconductors. Existence and uniqueness of global weak solutions are proven for the system with a higher-order nonlinear recombination-generation rate R. We also show that the global weak solution will converge to a unique equilibrium as time tends to infinity.
ARE INTRAUROTHELIAL LESIONS ASSOCIATED WITH MUSCLE-INVASIVE TRANSITIONAL CELL CARCINOMAS TRUE PRECURSORS?
Creators: name: Diaz-Cano, Salvador J.
name: A Blanes
name: J Rubio
name: A Matilla
name: JJ Sanchez-Carrillo
name: HJ Wolfe
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Molecular Biology
Cancer
Cell Biology

description: Background: The clonal relationship between low-grade urothelial dysplasia (LGUD) and carcinomas in situ (CIS) with muscle- invasive transitional cell carcinoma (TCC) remains unknown.
Methods: LGUD (18) and CIS (12) from 72 patients with muscle-invasive TCC (coexistent lesions in 5 patients) were selected and microdissected. DNA was extracted from dysplastic cells (LGUD and CIS) and invasive tumor cells located above (superficial) and below (deep) the muscularis mucosa and used to analyze the methylation pattern of androgen receptor alleles. The microsatellite patterns of TP53, RBI, WT1, and NFI were studied by PCR-denaturing gradient gel electrophoresis. The same areas were systematically s t u d i a p r the expression of Ki67 and cell cycle regulators (p53, p21 , pRBl), nuclear DNA content, and in situ end labeling. Appropriate controls were run in each case.
Results: Monoclonal patterns were revealed in CIS (6, loo%), invasive TCC (13, 100%), and LGUD (2, 20%), whereas polyclonal patterns were observed in LGUD only (8, 80%). CIS showed aneuploid DNA content and more microsatellite loci altered than the corresponding invasive compartments, always involving TP53 loci and expressing abnormal p53. In contrast, LGUD revealed diploid DNA content and microsatellite abnormalities in only 2 cases, one monoclonal (RBI) and one polyclonal (WT1 and NF1). Opposite kinetic patterns were observed for CIS (higher Ki-67 index, lower ISEL index) and LGUD (lower Ki-67 index, higher ISEL index).
Conclusions: These genetic findings suggest that CIS evolution is independent of muscle-invasive ?CC and that secondary CIS is not the precursor lesion of coexistent TCC. LGUD should not be closely connected with this molecular progression. The kinetic patterns would contribute to the accumulation of genetic abnormalities in CIS but not in LGU.
Structured Resonance in Stellar Evolution—A CODES Perspective on Elemental Constraints and Long-Term Galactic Phase Cycling
Creators: name: Bostick, Devin
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Physical cosmology
subject: Earth-sun relationship
subject: Neutron stars
subject: Stars, Celestial
subject: Space Research
subject: Space (interplanetary)
subject: Space exploration
subject: Space Simulation

description: Main CODES Paper with replicable, empirical, falsifiable tests = Link

 

Abstract: Structured Resonance in Stellar Evolution—A CODES Perspective on Elemental Constraints and Long-Term Galactic Phase Cycling

 

Stellar evolution has traditionally been modeled as a thermodynamic process dictated by mass-dependent fusion thresholds. However, this approach overlooks the deeper structural constraints imposed by chiral phase-locking and emergent resonance fields at galactic scales. This paper introduces the Chirality of Dynamic Emergent Systems (CODES) framework as a novel lens for understanding stellar evolution, particularly in explaining why low-mass stars, such as the Sun, terminate fusion at carbon-oxygen formation rather than progressing toward heavier elements.

We propose that the final elemental composition of a star is not simply a function of available fusion energy but is constrained by prime-number-based resonance gaps in nuclear binding energy. Carbon-12 and Oxygen-16 are not merely where fusion “stalls” in Sun-like stars but represent stable phase-locked nodes within a larger structured emergence pattern. We hypothesize that white dwarfs are not inert remnants but long-term phase-stabilized structures within the galactic coherence field, acting as low-entropy attractors in the ongoing mass-energy oscillation cycle (E → M → E).

Furthermore, we extend this model to the long-term fate of stellar matter, predicting that all elements will, over sufficiently long timescales, migrate toward higher-density phase states. The widely accepted cosmological assumption of universal heat death is challenged by the notion that structured emergence, rather than pure entropy dissipation, dominates at deep time scales. If correct, this suggests that all stellar matter, including that of the Sun, will ultimately phase-lock into condensation pathways leading toward black hole formation or equivalent high-density states.

We outline empirical tests for this hypothesis, including statistical clustering of white dwarf compositions, deviations in cooling rates due to weak-field resonance interactions, and galactic-scale simulations of stellar mass migration toward condensation nodes. If validated, this model provides a coherence-driven alternative to entropy-based cosmological evolution, redefining the lifecycle of stars and the ultimate trajectory of all matter in the universe.
Global solution to the three-dimensional compressible flow of liquid crystals
Creators: name: Hu, Xianpeng
name: Wu, Hao
Publisher: name: arXiv
Year: 2012
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35A05, 76A10, 76D03

description: The Cauchy problem for the three-dimensional compressible flow of nematic liquid crystals is considered. Existence and uniqueness of the global strong solution are established in critical Besov spaces provided that the initial datum is close to an equilibrium state $(1,{\bf 0}, \hat{\d})$ with a constant vector $\hat{\d}\in S^2$. The global existence result is proved via the local well-posedness and uniform estimates for proper linearized systems with convective terms.
Diffusion limit of kinetic equations for multiple species charged particles
Creators: name: Wu, Hao
name: Lin, Tai-Chia
name: Liu, Chun
Publisher: name: arXiv
Year: 2013
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 35Q99, 35B25, 45K05, 35J05

description: In ionic solutions, there are multi-species charged particles (ions) with different properties like mass, charge etc. Macroscopic continuum models like the Poisson-Nernst-Planck (PNP) systems have been extensively used to describe the transport and distribution of ionic species in the solvent. Starting from the kinetic theory for the ion transport, we study a Vlasov-Poisson-Fokker-Planck (VPFP) system in a bounded domain with reflection boundary conditions for charge distributions and prove that the global renormalized solutions of the VPFP system converge to the global weak solutions of the PNP system, as the small parameter related to the scaled thermal velocity and mean free path tends to zero. Our results may justify the PNP system as a macroscopic model for the transport of multi-species ions in dilute solutions.
description: substantial revision has being made
CRITICAL REAPPRAISAL OF PATHOLOGIC CRITERIA FOR THE DIAGNOSIS OF ADRENOCORTICAL PROLIFERATIVE LESIONS
Creators: name: Diaz-Cano, Salvador J.
name: M De Miguel
name: A Blanes
name: H Galera
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Cancer
Cell Biology

description: Introduction: This study compares three classification systems of adrenocortical tumors, i.e. Hough (HHS), Weiss (WS) and van Slooten (VSS), with a newly designed step-wise discriminant diagnostic system (SDDS) for accuracy, reproducibility, and reliability in a series of nodular hyperplasias (ACNH), adenomas (ACA), and carcinomas (ACC).
Design: We studied ACNH (82), ACA (78),and ACC (32), classified according to WHO criteria by three observers. Presence of metastases was the main malignancy criterion (mean follow-up 135 months). The systematic evaluation comprised more than 50 architectural and cytological variables. Significant variables were introduced in step-wise discriminant analyses with cross- validations.
Results: SDDS independent predictors were standard deviation of MFIHPF, anisokaryosis. appearance of remaining cortex, and stromal reaction (presence and type), which correctly classified 100.0% ACNH, 90.6% ACA, and 84.3% ACC. The other systems classified correctly 78.9% ACNH, 81.3% ACA, and 84.3% ACC with HHS, and 100.0% ACNH, 0.0% ACA, and 92.0% ACC with WS and VSS.
Conclusions: Mitotic figure counting variability is the most important malignancy criterion. Reliable diagnosis would require using SDDS as the most specific for malignancy, and WS or VSS as the most sensitive. SDDS is the most useful system to distinguish ACA (myxoid stromal reaction and anisokaryosis) from ACNH.
Computational Imaging Through Atmospheric Turbulence
Creators: name: Chimitt, Nicholas
name: Chan, Stanley H.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Since the seminal work of Andrey Kolmogorov in the early 1940's, imaging through atmospheric turbulence has grown from a pure scientific pursuit to an important subject across a multitude of civilian, space-mission, and national security applications. Fueled by the recent advancement of deep learning, the field is further experiencing a new wave of momentum. However, for these deep learning methods to perform well, new efforts are needed to build faster and more accurate computational models while at the same time maximizing the performance of image reconstruction.
 The book is written primarily for image processing engineers, computer vision scientists, and engineering students who are interested in the field of atmospheric turbulence, statistical optics, and image processing. The book can be used as a graduate text, or advanced topic classes for undergraduates.
Mayoury and Pheuiphanh Ngaosyvathn: Kith and Kin Politics: The Relationship between Laos and Thailand
Creators: name: Grabowsky, Volker
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 58 (1996): ASIEN (Januar)
MELANOCYTES IN EPITHELIAL NEST: A DIAGNOSTIC CLUE FOR TRICHOEPITHELIOMAS / TRICHOBLASTOMAS
Creators: name: Diaz-Cano, Salvador J.
name: Z Aly
name: R Cerio
name: L Pozo
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Cancer

description: Introduction: Epithelial pilar neoplasms are relatively rare and heterogeneous, revealing pigment exceptionally. The presence of melanocytes has not been studied and there is no systematic evaluation of histologic features, resulting in a low diagnostic reproducibility.
Methods: We selected trichoepithelioma/trichoblastoma (46) with appropriate archival material. We systematically evaluated growth pattern (multifocal or not), type of squamous differentiation, cytological evidence of catagen, presence of dual cell population, epithelial and stromal pigment, epithelial and stromal calcification, stromal reaction (myxoid, lamellar fibrosis, hyalinization), nuclear features, and mitotic figurell0 HPF. The presence of melanocyte was investigated by immunohistochemistry (S100, HMB-45). Results: All cases revealed a dual population, epithelial cells revealing bland nuclei and distinct nucleolus and interstitial cells in the nests showing hyperchromatic spindle nuclei, The latter were revealed S-100- and HMB-45-positive. Epithelial pigment also correlated with catagen cytological features (71%). Tumors revealing multifocal growth pattern showed mitotic figures (80%), while these were less frequently present in non-multifocal neoplasms (49%). The other histological variables revealed no correlation.
Conclusions: Melanocyte colonization is a very common finding in trichoepitheliomas-trichoblastomas and can help identifying these neoplasms. Multifocal growth pattern should be investigated especially in mitotically active neoplasms, for which a complete excision is more difficult.
Global Well-posedness of the Two Dimensional Beris-Edwards System with General Laudau-de Gennes Free Energy
Creators: name: Liu, Yuning
name: Wu, Hao
name: Xu, Xiang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q35, 35Q30, 76D03, 76D05

description: In this paper, we consider the Beris-Edwards system for incompressible nematic liquid crystal flows. The system under investigation consists of the Navier-Stokes equations for the fluid velocity $\mathbf{u}$ coupled with an evolution equation for the order parameter $Q$-tensor. One important feature of the system is that its elastic free energy takes a general form and in particular, it contains a cubic term that possibly makes it unbounded from below. In the two dimensional periodic setting, we prove that if the initial $L^\infty$-norm of the $Q$-tensor is properly small, then the system admits a unique global weak solution. The proof is based on the construction of a specific approximating system that preserves the $L^\infty$-norm of the $Q$-tensor along the time evolution.
Changing Children’s Chances Project Overview
Creators: name: Goldfeld, Sharon
name: O'Connor, Elodie
name: Guo, Shuaijun
name: Pham, Cindy
name: Gray, Sarah
Publisher: name: Murdoch Childrens Research Institute
Year: 2024
Subjects: Health Sciences

description: Reducing disadvantage in early childhood would have immediate and lasting benefits for children, families and communities. The Changing Children’s Chances project has already shown that we can almost halve problems with children’s health and development if we address disadvantage. Now the Changing Children’s Chances researchers are modelling how combining or ‘stacking’ interventions can reduce inequities in children’s health and development – particularly for those experiencing the greatest vulnerability or disadvantage.
Frank Holl: Der Langkawi-Archipel Nordwest Malaysia. Regionalentwicklung eines Peripherraumes unter dem Einfluß des Tourismus
Creators: name: Schimany, Peter
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 58 (1996): ASIEN (Januar)
Changing Children’s Chances Project Overview
Creators: name: Goldfeld, Sharon
name: O'Connor, Elodie
name: Guo, Shuaijun
name: Pham, Cindy
name: Gray, Sarah
Publisher: name: Murdoch Childrens Research Institute
Year: 2023
Subjects: Health Sciences

description: Reducing disadvantage in early childhood would have immediate and lasting benefits for children, families and communities. The Changing Children’s Chances project has already shown that we can almost halve problems with children’s health and development if we address disadvantage. Now the Changing Children’s Chances researchers are modelling how combining or ‘stacking’ interventions can reduce inequities in children’s health and development – particularly for those experiencing the greatest vulnerability or disadvantage.
Tritangents to smooth sextic curves
Creators: name: Degtyarev, Alex
Publisher: name: arXiv
Year: 2019
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14J28, 14H50, 14N20, 14N25

description: We prove that a smooth plane sextic curve can have at most 72 tritangents, whereas a smooth real sextic may have at most 66 real tritangents.
description: Final version accepted by Annales de l'Institut Fourier
Orbital Edelstein effect of electronic itinerant orbital motion at edges
Creators: name: Lee, Jongjun M.
name: Park, Min Ju
name: Lee, Hyun-Woo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In the study of orbital angular momentum (OAM), the focus has been predominantly on the intra-atomic contribution. However, recent research has begun to shift towards exploring the inter-atomic contribution to OAM dynamics. In this paper, we investigate the orbital Edelstein effect (OEE) arising from the inter-atomic OAM at the edges. We explore the OAM texture within edge states and unveil the OAM accumulation at the edges using several lattice models based on the $s$ orbital. By comparing slabs with differently shaped edges, we not only clarify the role of electron wiggling motion in shaping OAM texture but also highlight the absence of bulk-boundary correspondence in the accumulation process. The topological insulator and higher-order topological insulator models further confirm these findings and provide evidence for the relationship between the higher-order topology and the OEE. Our study advances the comprehension of orbital physics and extends its scope to higher-order topological insulators.
description: 9 pages, 4 figures, Physical Review B accepted version
Actuator selection for variable camber foils
Creators: name: Madden, John D. W.
Publisher: name: Society of Photo-Optical Instrumentation Engineers (SPIE)
Year: 2011

description: A number of polymer based actuator technologies have emerged over the past decade. How do these compare with traditional actuators and are there applications for which they are appropriate? Some of the answers to these questions are provided by outlining the rationale for employing an electroactive polymer to control hydrodynamic surfaces. The surfaces are sections of propeller blades whose trailing edges are deflected in order to change camber. The objective is to insert the actuators into the blades. High work per unit volume is required of the actuators. The ideal actuator technologies also feature relatively large strains in order to deflect the trailing edges with minimal mechanical amplification. It is argued that the high work densities, flexibility in shaping and the ability to hold a force without expending energy (catch state) provide electroactive polymers with advantages over electromagnetic actuators, which also lack the torque to directly drive the blade deflection. Candidate actuators are compared, including electroactive polymers, shape memory alloys, magnetostrictives and traditional piezoceramics. Selections are made on the bases of work density, strain, existence of a catch state, drive voltage and cost. It is suggested that conducting polymer actuators are best suited for the variable camber application. It is also argued that in general electroactive polymers are well-suited for applications in which actuator volume or mass are very limited, catch states are desired, cycle life is moderate to low, or noise cannot be tolerated. Some electroactive polymers also feature low voltage operation, and may be biocompatible. Copyright 2004 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Werlen, B.- S. Wälty (Hg.): Kulturen und Raum. Theoretische Ansätze und empirische Kulturforschung in Indonesien (Festschrift für Professor A. Leemann)
Creators: name: R. Zimmermann, Gerd
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: ASIEN: The German Journal on Contemporary Asia, Nr. 58 (1996): ASIEN (Januar)
Degenerate processes killed at the boundary of a domain
Creators: name: Benaïm, Michel
name: Champagnat, Nicolas
name: Oçafrain, William
name: Villemonais, Denis
Publisher: name: arXiv
Year: 2021
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60J25, 60J60, 60F, 60B10, 35H10, 37A25, 37A30, 47A35, 47A75

description: We investigate certain properties of degenerate Feller processes that are killed when exiting a relatively compact set. Our main result provides general conditions ensuring that such a process possesses a (possibly non unique) quasi stationary distribution. Conditions ensuring uniqueness and exponential convergence are discussed. The results are applied to nonelliptic and hypoelliptic stochastic differential equations.
Global Weak Solutions to the Navier-Stokes-Darcy-Boussinesq System for Thermal Convection in Coupled Free and Porous Media Flows
Creators: name: Wang, Xiaoming
name: Wu, Hao
Publisher: name: arXiv
Year: 2020
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35D30, 35K61, 76D03, 76D05, 76S05

description: We study the Navier-Stokes-Darcy-Boussinesq system that models the thermal convection of a fluid overlying a saturated porous medium in a general decomposed domain. In both two and three spatial dimensions, we first prove the existence of global weak solutions to the initial boundary value problem subject to the Lions and Beavers-Joseph-Saffman-Jones interface conditions. The proof is based on a proper time-implicit discretization scheme combined with the Leray-Schauder principle and compactness arguments. Next, we establish a weak-strong uniqueness result such that a weak solution coincides with a strong solution emanating from the same initial data as long as the latter exists.
description: 36 pages, to appear in Adv. Differential Equations
CELL KINETICS CONTRIBUTIONS TO THE DIFFERENTIAL GENETIC PATTERN OF C-CELL AND ADRENAL MEDULLARY HYPERPLASIAS IN MULTIPLE ENDOCRINE NEOPLASIA 2A
Creators: name: Diaz-Cano, Salvador J.
name: M De Miguel
name: Blanes, Alfredo
name: R Tashjian
Publisher: name: figshare
Year: 2012
Subjects: subject: Medicine
subject: Molecular Biology
subject: Cancer
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences

description: Introduction: Cell kinetic contributions to the genetic heterogeneity of C-cell hyperplasias (CCH) and adrenal medullary hyperplasias (AMH) in multiple endocrine neoplasia 2A remain unknown.
Methods: We selected 22 CCH foci and 34 AMH nodules from MEN-2A kindred (RET mutation in codon 634). DNA extracted from microdissected samples was used for microsatellite analysis of TP53, RB1, WT1, and NF1 by PCR-denaturing gradient gel electrophoresis. Ki-67, in situ end labeling (ISEL), and kinetic (Ki-67/1SEL) indices were calculated in each sample. Only informative cases were included.
Results: CCH revealed higher and more homogeneous incidence of loss of heterozygosity (LOH) for [ TP53 (I 2120, 60%), and R67 (8114, 57%)1 than AMH [TP53 (9/31,29%), RBI (3125, 12%), WTI (9128, 32%), and NF7 (9119, 47%)]. Coexistent LOH in $2 loci were observed in 5/20 CCH and 6/31 AMH, always involving TP53 in CCH and NF7 in AMH. Kinetic indices were significantly higher in lesions accumulating multiple LOH than in lesions with single LOH (261.25 VS. 169.38), due to decreased ISEL indices.
Conclusions: MEN 2A lesions accumulating somatic genetic abnormalities reveal the most advantageous kinetic profile essentially due to down-regulated apoptois. Differential genetic profile contributes to that pattern, involving TP53/RB1 in CCH and NF1 in AMH.
Large strain actuation in polypyrrole actuators
Creators: name: Vandesteeg, Nathan A.
name: Rinderknecht, Derek
name: Anquetil, Patrick A.
name: Hunter, Ian W.
name: Madden, John D. W.
Publisher: name: Society of Photo-Optical Instrumentation Engineers (SPIE)
Year: 2011

description: A typical limitation of polypyrrole based conducting polymer actuators is the low achievable active linear strains (2 % recoverable at 10 MPa, 7 % max) that these active materials exhibit when activated in a common propylene carbonate / tetraethylammonium hexafluorophosphate electrolyte. Mammalian skeletal muscle, on the other hand, exhibits large recoverable linear strains on the order of 20%. Such large linear strains are desirable for applications in life-like robotics, artificial prostheses or medical devices. We report herein the measurement of recoverable linear strains in excess of 14 % at 2.5 MPa (20 % max) for polypyrrole activated in the 1-butyl-3-methyl imidazolium tetrafluoroborate liquid salt electrolyte. This advancement in conducting polymer actuator technology will impact many engineering fields, where a lightweight, large displacement actuator is needed. Benefits and trade offs of utilizing ionic liquid electrolytes for higher performance polypyrrole actuation are discussed. Copyright 2004 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
The H-graph with equal masses in terms of multiple polylogarithms
Creators: name: Kreer, Philipp Alexander
name: Weinzierl, Stefan
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The initial phase of the inspiral process of a binary system producing gravitational waves can be described by perturbation theory. At the third post-Minkowskian order a two-loop double box graph, known as H-graph contributes. We consider the case where the two objects making up the binary system have equal masses. We express all master integrals related to the equal-mass H-graph up to weight four in terms of multiple polylogarithms. We provide a numerical program which evaluates all master integrals up to weight four in the physical regions with arbitrary precision.
description: 19 pages, v2: version to be published, v3: boundary value for $J_{25}^{(4)}$ corrected
ARE THE INTRAEPIDERMAL HIGH-GRADE MELANOCYTIC LESIONS THE DIRECT PRECURSORS OF INVASIVE MALIGNANT MELANOMAS?
Creators: name: Diaz-Cano, Salvador J.
name: E Husain
name: M De Miguel
name: A Blanes
name: R Cerio
name: L Pozo
Publisher: name: figshare
Year: 2012
Subjects: Medicine
Molecular Biology
Cancer
Cell Biology

description: Introduction: No topographic evaluation on cell kinetic and cell cycle regulators is available for atypical melanocytic nevi (AMN) and melanomas in situ (MIS).
Methods: We selected AMN (92 low-grade, 31 high-grade), MIS (10), malignant melanomas (MM, 15 radial growth phase and 27 vertical growth phase), and melanocytic nevi (15 junctional, 20 compound). Junctional and dermal (above and below 0.76mm) immunostainings for Ki-67, p53, p21 WAF1 , and p27Kip1 and in situ end labeling (ISEL) for apoptosis were scored independently, Statistics included analysis of variance and Student f-test (significant if Pc0.05).
Results: All markers revealed a decreasing junctional-dermal gradient. Ki-67 was high and mainly restricted to the junction in high-grade AMN. Junctional p53 expression was significantly higher in high-grade AMN and MIS and revealed an inverse correlation with p21WAF1 and p27WAF1, while it was significantly decreased in MM (9.56%). Only high-grade AMN revealed junctional ISEL indices significantly lower than dermal ones (2.21% vs. 4.01%).
Concluslons: Abnormal p53 expression drives high-grade AMN and MIS, which is dissociated from CDK inhibitors (p2lWAF1 and p27KIP1, especially for MIS. lnvasive MM seems to be TP53-independent.
Addressing disadvantage to optimise children's development in Australia
Creators: name: Goldfeld, Sharon
name: O'Connor, Elodie
name: Gray, Sarah
name: O'Connor, Meredith
Publisher: name: Murdoch Childrens Research Institute
Year: 2024
Subjects: Health Sciences

description: The Changing Children’s Chances project aimed to identify patterns in children’s experiences of disadvantage over time and quantify the long-lasting impact of disadvantage. 
It used four lenses related to social determinants – sociodemographic factors, geographic environments, health conditions, and risk factors – to measure children’s exposure to disadvantage and identify its impact on important aspects of children’s development (social-emotional, cognitive, and physical functioning).
This study helps to reveal the extent and impact of disadvantage on children’s development. The findings indicate that some aspects of disadvantage are particularly relevant for some developmental outcomes, which may inform targeted strategies for reducing exposure to disadvantage.
Excavations at Red Castle, Thetford
Creators: name: Knocker, G M
Publisher: name: Archaeology Data Service
Year: 2020

description: Norfolk Archaeology, 34 (2), 119-186
description: TL 8683. Graves of Middle Saxon date had been cut through RB and Pagan Saxon material on a site by the junction of the Little Ouse river and the town ditch. Eighty-five skeletons were recovered, detailed anthropometrical and pathological examination indicating that the principal diseases were osteoarthritis and paradontal dental abscesses. The skulls were round, perhaps indicating a Frisian origin, with asymmetry ascribed to cradle binding. The decapitated skulls of a long-headed man and woman had been carefully reburied in separate stone-lined hollows. Cooking hearths were strewn with Middle Saxon pottery. In the 11th cent church the S and E walls of the chancel and vestry were of rubble, with false-ashlar plastering and oolite quoins. Inside were traces of a wooden building. Near the altar lay a fragment of bronze censer and piece of Laconian porphyry. The church was covered by a strong revetted bank and ditch of a circular enclosure with inner perimeter track. No pottery later than about AD 1300 was found. DFR
Addressing disadvantage to optimise children's development in Australia
Creators: name: Goldfeld, Sharon
name: O'Connor, Elodie
name: Gray, Sarah
name: O'Connor, Meredith
Publisher: name: Murdoch Childrens Research Institute
Year: 2022
Subjects: Health Sciences

description: The Changing Children’s Chances project aimed to identify patterns in children’s experiences of disadvantage over time and quantify the long-lasting impact of disadvantage. 
It used four lenses related to social determinants – sociodemographic factors, geographic environments, health conditions, and risk factors – to measure children’s exposure to disadvantage and identify its impact on important aspects of children’s development (social-emotional, cognitive, and physical functioning).
This study helps to reveal the extent and impact of disadvantage on children’s development. The findings indicate that some aspects of disadvantage are particularly relevant for some developmental outcomes, which may inform targeted strategies for reducing exposure to disadvantage.
The bloomery site at West Runton, Norfolk
Creators: name: Tylecote, R F
Publisher: name: Archaeology Data Service
Year: 2020

description: Norfolk Archaeology, 34 (2), 187-214
description: TG 183414; 174417. A 9th-12th cent bloomery furnace was located by magnetic survey and excavated in 1964. The working area had been intensely used during the currency of Thetford ware. A roasting-hearth and the lower part of a clay-lined smelting furnace survived: the indications of a low shaft suggest affinities with furnaces at Stamford and High Bishopley, Co Durham. Smelting, probably with the addition of manganese-rich pan, gave a yield of finished iron one-quarter by weight of the roasted ore. Slag was tapped during the process. 1200yd from the smelting site two mine-pits and the unworked ground between them were sectioned to determine the supply of ore. A typical pit might produce 5cu.ft of nodules (weighing 600lb before roasting) in about 270cu.ft of sand, much of the ore coming from a pan layer within 3ft of the original ground surface. A table shows analyses of ferruginous material formerly used for building material in Norfolk and generally similar to the pan at West Runton. DWC
Sparse Mixture Models inspired by ANOVA Decompositions
Creators: name: Hertrich, Johannes
name: Ba, Fatima Antarou
name: Steidl, Gabriele
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: Inspired by the analysis of variance (ANOVA) decomposition of functions we propose a Gaussian-Uniform mixture model on the high-dimensional torus which relies on the assumption that the function we wish to approximate can be well explained by limited variable interactions. We consider three approaches, namely wrapped Gaussians, diagonal wrapped Gaussians and products of von Mises distributions. The sparsity of the mixture model is ensured by the fact that its summands are products of Gaussian-like density functions acting on low dimensional spaces and uniform probability densities defined on the remaining directions. To learn such a sparse mixture model from given samples, we propose an objective function consisting of the negative log-likelihood function of the mixture model and a regularizer that penalizes the number of its summands. For minimizing this functional we combine the Expectation Maximization algorithm with a proximal step that takes the regularizer into account. To decide which summands of the mixture model are important, we apply a Kolmogorov-Smirnov test. Numerical examples demonstrate the performance of our approach.