cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effect of semicrystalline copolymers in solid dispersions of pioglitazone hydrochloride: in vitro-in vivo correlation
Creators: name: Swain, Ranjit Prasad
name: Subudhi, Bharat Bhusan
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Objective: The study was aimed to improve the dissolution and bioavailability of developed stable amorphous solid dispersions (SDs) of pioglitazone hydrochloride (PGH), a poorly water-soluble drug. Significance: Poor aqueous solubility of PGH was overcome by the design of SDs. Level A correlation demonstrated between in vitro release and bioavailability of PGH, suggest its biowaiver potential. Methods: The effects of semicrystalline copolymers (poloxamer 407 and gelucire 50/13) and methods of preparations on dissolution behavior, in vivo performance, and stability of PGH SDs were investigated. All the SDs were characterized by FTIR, TGA, DSC, XRD, and SEM. Results: FTIR and TGA showed the compatibility with the polymers. The significant change in melting pattern of the PGH observed in the DSC thermograms supported by XRD patterns & SEM indicated a change from a crystalline to an amorphous state. Gelucire 50/13 was observed to have greater ability to form SDs than poloxamer 407 in solvent evaporation method (SM). Prevention of recrystallization during storage suggested stability of the formulation. Gelucire 50/13 based SD, prepared by SM remarkably increased the dissolution within 15 min (87.27 ± 2.25%) and was supported by dissolution parameters (Q15, IDR, RDR, % DE, f1, f2). These SDs showed pH-dependent solubility. In vivo test showed significantly (p < .05) higher AUC0–t and Cmax, which were about 3.17 and 4.34 times that of the pure drug respectively. Conclusion: Gelucire 50/13 was found to be a suitable carrier for SM for preparation of SDs of PGH as evident from increased dissolution and bioavailability.
Effect of semicrystalline copolymers in solid dispersions of pioglitazone hydrochloride: in vitro-in vivo correlation
Creators: name: Swain, Ranjit Prasad
name: Bhusan Subudhi, Bharat
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Objective: The study was aimed to improve the dissolution and bioavailability of developed stable amorphous solid dispersions (SDs) of pioglitazone hydrochloride (PGH), a poorly water-soluble drug. Significance: Poor aqueous solubility of PGH was overcome by the design of SDs. Level A correlation demonstrated between in vitro release and bioavailability of PGH, suggest its biowaiver potential. Methods: The effects of semicrystalline copolymers (poloxamer 407 and gelucire 50/13) and methods of preparations on dissolution behavior, in vivo performance, and stability of PGH SDs were investigated. All the SDs were characterized by FTIR, TGA, DSC, XRD, and SEM. Results: FTIR and TGA showed the compatibility with the polymers. The significant change in melting pattern of the PGH observed in the DSC thermograms supported by XRD patterns & SEM indicated a change from a crystalline to an amorphous state. Gelucire 50/13 was observed to have greater ability to form SDs than poloxamer 407 in solvent evaporation method (SM). Prevention of recrystallization during storage suggested stability of the formulation. Gelucire 50/13 based SD, prepared by SM remarkably increased the dissolution within 15 min (87.27 ± 2.25%) and was supported by dissolution parameters (Q15, IDR, RDR, % DE, f1, f2). These SDs showed pH-dependent solubility. In vivo test showed significantly (p < .05) higher AUC0–t and Cmax, which were about 3.17 and 4.34 times that of the pure drug respectively. Conclusion: Gelucire 50/13 was found to be a suitable carrier for SM for preparation of SDs of PGH as evident from increased dissolution and bioavailability.
Nutrient Timing in Resistance-Trained Women
Creators: name: Pihoker, Alexis
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: The purpose of this study was to evaluate the effects of different peri-workout nutrition strategies on strength, body composition, and metabolism in trained females.  Young, trained females (n=43) completed body composition and strength testing before and after training.  Participants were randomized into three groups using baseline leg press strength; pre-exercise supplementation of a protein-carbohydrate shake (PRE), post-exercise supplementation (POST), or a control group (CON).  Following baseline testing, participants were trained twice per week for six weeks using high intensity resistance training.  At the first and last training, metabolic testing was completed before and after exercise.  There were significant main effects for time for LM (p=0.003) and %fat (p<0.0005).  All three groups experienced significant increases in strength.  There were no significant between groups differences for metabolic measurements (p>0.05).   These results demonstrate that peri-workout nutrition is potentially important for body composition, but either a PRE or POST strategy is effective.
Development and validation of a sensitive HPLC-HESI-MS/MS method for quantitative determination of bitopertin in rat and marmoset plasma
Creators: name: Frouni, Imane
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Life Sciences
subject: bioanalysis
subject: bitopertin
subject: HPLC-HESI-MS/MS
subject: marmoset plasma
subject: pharmacokinetics
subject: rat plasma

description: The objective of this study was to develop and validate a sensitive and selective high-performance liquid chromatography coupled with heat assisted electrospray ionisation tandem mass spectrometry (HPLC-HESI-MS/MS) assay to quantify bitopertin in the rat (Sprague-Dawley) and the common marmoset (Callithrix jacchus) plasma after administration of 1.0 mg/kg subcutaneously.
Egocentric Field-of-View Localization Using First-Person Point-of-View Devices
Creators: name: Bettadapura, Vinay
name: Essa, Irfan
name: Pantofaru, Caroline
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: We present a technique that uses images, videos and sensor data taken from first-person point-of-view devices to perform egocentric field-of-view (FOV) localization. We define egocentric FOV localization as capturing the visual information from a person's field-of-view in a given environment and transferring this information onto a reference corpus of images and videos of the same space, hence determining what a person is attending to. Our method matches images and video taken from the first-person perspective with the reference corpus and refines the results using the first-person's head orientation information obtained using the device sensors. We demonstrate single and multi-user egocentric FOV localization in different indoor and outdoor environments with applications in augmented reality, event understanding and studying social interactions.
description: 8 pages in Proceedings of the 2015 IEEE Winter Conference on Applications of Computer Vision (WACV 2015)
Estimating Prognosis of Patients with Kidney Cancer
Creators: name: Robert, Anita
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2023
Subjects: prognostic model
cancer

description: Kidney Cancer has numerous subtypes with Clear Cell Renal Cell Carcinoma (ccRCC) being the most common. Pre-existing prognostic models have not been validated in Canadian patients for recurrence free survival (RFS) and other outcomes. We conducted four studies: 1) externally validated pre-existing RCC prognostic models; 2) assessed the impact of baseline hazard function miscalibration on model assessment; 3) created new models and risk groups for RFS in non-metastatic ccRCC patients; 4) compared new risk groups to existing Canadian guidelines and created new imaging schedules. Pre-existing model performance varied considerably with some models performing well. The effect of baseline hazard function miscalibration varied across distribution shapes but the calibration slope was useful in relatively ranking prognostic model performance. The CKCis prognostic model and risk groups performed better than the existing CUA risk groups. Based on CKCis risk groups fewer scans are recommended in low-risk patients and more scans are recommended in higher risk patients. External validation of the CKCis model is required to assess clinical utility in different populations.
Visualizing extremal positive maps in unital and trace preserving form
Creators: name: Hansen, Leif Ove
name: Myrheim, Jan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We define an entanglement witness in a composite quantum system as an observable having nonnegative expectation value in every separable state. Then a state is entangled if and only if it has a negative expectation value of some entanglement witness. Equivalent representations of entanglement witnesses are as nonnegative biquadratic forms or as positive linear maps of Hermitian matrices. As reported elsewhere, we have studied extremal entanglement witnesses in dimension $3\times 3$ by constructing numerical examples of generic extremal nonnegative forms. These are so complicated that we do not know how to handle them other than by numerical methods. However, the corresponding extremal positive maps can be presented graphically, as we attempt to do in the present paper. We understand that a positive map is extremal when the image of $\mathcal{D}$, the set of density matrices, fills out $\mathcal{D}$ maximally, in a certain sense. For the graphical presentation of a map we transform it to a standard form where it is unital and trace preserving. We present an iterative algorithm for the transformation, which converges rapidly in all our numerical examples and presumably works for any positive map. This standard form of an entanglement witness is unique up to unitary product transformations.
description: 31 pages, 21 figures
YIELDS OF, AND P, K, Ca, Mg UPTAKES BY, CROPS GROWN IN AN EXPERIMENT TESTING THE EFFECTS OF ADDING PEAT TO A SANDY LOAM SOIL AT WOBURN, 1963-77, Rothamsted Experimental Station Report for 1978 Part 2
Creators: name: A. E. JOHNSTON And P. C. BROOKES
Publisher: name: Lawes Agricultural Trust
Year: 1979
Subjects: subject: rothamsted research
subject: crop yield
subject: woburn experimental farm

description: Scanned PDF of YIELDS OF, AND P, K, Ca, Mg UPTAKES BY, CROPS GROWN IN AN EXPERIMENT TESTING THE EFFECTS OF ADDING PEAT TO A SANDY LOAM SOIL AT WOBURN, 1963-77, part of Rothamsted Experimental Station Report for 1978 Part 2
Raising the bar for instructional outcomes: Towards transformative learning experiences.
Creators: name: Wilson, Brent G.
name: Parrish, Patrick
name: Veletsianos, George
Publisher: name: Vancouver Island University - Royal Roads University
Year: 2008
Subjects: Instructional systems--Design
Transformative learning

description: Most instructional technologists understand that instruction aims to be effective, efficient, and appealing. These three quality indicators have proven useful in establishing desired outcomes. In this article we suggest an expanded set of indicators, with more attention to social impact, engagement, and the learner’s experience. By broadening and deepening our expectations, we hope to encourage more research on instruction leading to powerful or transformative learning.
Cytotoxic effects of manganese oxide nanoparticles in combination with microbial components on intestinal epithelial cells
Creators: name: Wannemuehler, Michael
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Life Sciences
subject: Cytotoxicity
subject: mitochondrial respiratory space capacity
subject: MnO nanoparticles
subject: Mode K epithelial cells

description: The data provided supports the uploaded manuscript title. The data are from a series of in vitro assays evaluating the impact of MnO2 nanoparticles on the function of an intestinal epithelial cell line and were used to generate the figures in the manuscript.
Reactivation from the Ni-B state in [NiFe] hydrogenase of Ralstonia eutropha is controlled by reduction of the superoxidised proximal cluster
Creators: name: Radu, Valentin
name: Frielingsdorf, Stefan
name: Lenz, Oliver
name: Jeuken, Lars J. C.
Publisher: name: Technische Universität Berlin
Year: 2016
Subjects: subject: 540 Chemie und zugeordnete Wissenschaften

description: The tolerance towards oxic conditions of O-2-tolerant [NiFe] hydrogenases has been attributed to an unusual [4Fe-3S] cluster that lies proximal to the [NiFe] active site. Upon exposure to oxygen, this cluster converts to a superoxidised (5+) state, which is believed to secure the formation of the so-called Ni-B state that is rapidly reactivated under reducing conditions. Here, the reductive reactivation of the membrane-bound [NiFe]-hydrogenase (MBH) from Ralstonia eutropha in a native-like lipid membrane was characterised and compared to a variant that instead carries a typical [4Fe-4S] proximal cluster. Reactivation from the Ni-B state was faster in the [4Fe-4S] variant, suggesting that the reactivation rate in MBH is limited by the reduction of the superoxidised [4Fe-3S] cluster. We propose that the [4Fe-3S] cluster plays a major role in protecting MBH by blocking the reversal of electron transfer to the [NiFe] active site, which would produce damaging radical oxygen species.
JSJ decompositions of groups
Creators: name: Guirardel, Vincent
name: Levitt, Gilbert
Publisher: name: arXiv
Year: 2016
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 20E08, 20E34, 20F65, 57M07, 20E06

description: This is an account of the theory of JSJ decompositions of finitely generated groups, as developed in the last twenty years or so. We give a simple general definition of JSJ decompositions (or rather of their Bass-Serre trees), as maximal universally elliptic trees. In general, there is no preferred JSJ decomposition, and the right object to consider is the whole set of JSJ decompositions, which forms a contractible space: the JSJ deformation space (analogous to Outer Space). We prove that JSJ decompositions exist for any finitely presented group, without any assumption on edge groups. When edge groups are slender, we describe flexible vertices of JSJ decompositions as quadratically hanging extensions of 2-orbifold groups. Similar results hold in the presence of acylindricity, in particular for splittings of torsion-free CSA groups over abelian groups, and splittings of relatively hyperbolic groups over virtually cyclic or parabolic subgroups. Using trees of cylinders, we obtain canonical JSJ trees (which are invariant under automorphisms). We introduce a variant in which the property of being universally elliptic is replaced by the more restrictive and rigid property of being universally compatible. This yields a canonical compatibility JSJ tree, not just a deformation space. We show that it exists for any finitely presented group. We give many examples, and we work throughout with relative decompositions (restricting to trees where certain subgroups are elliptic).
description: Revision with an index added, and other minor modifications. Replaces and expands arXiv:0911.3173 and arXiv:1002.4564. To appear in Asterisque. 128 pages
Blue-winged teals in Guatemala and their potential role in the ecology of H14 subtype influenza A viruses
Creators: name: Perez, Daniel R
Publisher: name: Zenodo
Year: 2023

description: Supplementary material associated with manuscript titled "Blue-winged teals in Guatemala and their potential role in the ecology of H14 subtype influenza A viruses" by Ortiz et al and in which D.R. Perez is the corresponding author.
description: Project funded by National Institutes of Health, US under contract # HHSN272201400008C
Charge-exchange resonances and restoration of the Wigner SU(4)-symmetry in heavy and superheavy nuclei
Creators: name: Lutostansky, Yu. S.
name: Tikhonov, V. N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Energies of the giant Gamow-Teller and analog resonances - $E_{\rm G}$ and $E_{\rm A}$, are presented, calculated using the microscopic theory of finite Fermi system. The calculated differences $ΔE_{\rm G-A}=E_{\rm G}-E_{\rm A}$ go to zero in heavier nuclei indicating the restoration of Wigner SU(4)-symmetry. The calculated $ΔE_{\rm G-A}$ values are in good agreement with the experimental data. The average deviation is 0.30 MeV for the 33 considered nuclei for which experimental data is available. The $ΔE_{\rm G-A}$ values were calculated for heavy and superheavy nuclei up to the mass number $A $= 290. Using the experimental data for the analog resonances energies, the isotopic dependence of the difference of the Coulomb energies of neighboring nuclei isobars analyzed within the SU(4)-approach for more than 400 nuclei in the mass number range of $A$ = 3 - 244. The Wigner SU(4)-symmetry restoration for heavy and superheavy nuclei is confirmed. It is shown that the restoration of SU(4)-symmetry does not contradict the possibility of the existence of the "island of stability" in the region of superheavy nuclei.
description: 5 pages, 2 figures
Comparison of Treatment Result and Compliance Between Private Practice Medicaid and Non-Medicaid Orthodontic Patients
Creators: name: Dickens, Steven
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Treatment result and compliance for orthodontic Medicaid patients was assessed and compared to non-Medicaid patients of similar initial severity. All 55 practices providing orthodontic treatment covered by Medicaid were asked to submit their last five Medicaid cases and five non-Medicaid cases of similar initial treatment complexity. Nine practices agreed to participate. Initial models, final models, and progress notes were obtained for all subjects. Casts were scored using the peer assessment rating (PAR) index to obtain treatment result data. Progress notes were reviewed for compliance data. No significant differences were seen between the Medicaid and non-Medicaid groups based on initial PAR, final PAR, or the percent of PAR reduction. No significant compliance differences were seen based on broken appointments, broken appliances, or number of poor oral hygiene comments. The Medicaid and non-Medicaid patients in our study did not differ significantly in the effectiveness of treatment received or their compliance with treatment.
Signatures of Vibrational Strong Coupling in Raman Scattering
Creators: name: del Pino, Javier
name: Feist, Johannes
name: García-Vidal, F. J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this Letter we analyze theoretically how the emergence of collective strong coupling between vibrational excitations and confined cavity modes affects Raman scattering processes. This work is motivated by recent experiments [Shalabney et al., Angew. Chemie 54, 7971 (2015)], which reported enhancements of up to three orders of magnitude in the Raman signal. By using different models within linear response theory, we show that the total Raman cross section is maintained constant when the system evolves from the weak-coupling limit to the strong-coupling regime. A redistribution of the Raman signal among the two polaritons is the main fingerprint of vibrational strong coupling in the Raman spectrum.
description: 5 pages, 3 figures
Konzeption und Implementation des Aufbaus eines Suchmaschinenindexes für Solr im bibliothekarischen Kontext
Creators: name: Obenland, Oliver
Publisher: name: Universität Tübingen
Year: 2017
Subjects: subject: Solr , Suchmaschine , Register
subject: 004
subject: 020

description: Diese Arbeit befasst sich mit der Struktur und dem Betrieb von VuFind, das eine bibliographische Suchmaschine darstellt. VuFind wird als Open-Source-Projekt entwickelt und mittlerweile von mehreren hundert Bibliotheken weltweit genutzt. Außerdem wird SolrMarc, ein Teilprojekt von VuFind, analysiert und überarbeitet, wodurch die Effizienz dieses Programmes erhöht wird.
Démocratie raciale et telenovelas brésiliennes : Une analyse des représentations télévisuelles des Afro-Brésiliens et leurs effets sociopolitiques
Creators: name: Catherina, Botelho Viveiros
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Démocratie raciale
Telenovelas
Afro-Brésiliens
Médias
Démocratie
Violence
Discrimination

description: Les telenovelas brésiliennes ont un pouvoir de représentation important au Brésil ; elles permettent de représenter une variété de thématiques sociales et de groupes sociaux et peuvent avoir un impact important sur les relations sociales dans la société. Selon plusieurs auteurs, la capacité représentative des telenovelas fait en sorte que ces émissions de télévision possèdent une capacité singulière à représenter et à combattre les inégalités dans la société. En effet, Samantha Nogueira-Joyce et Mauro Porto avancent que les telenovelas brésiliennes ont une aptitude à représenter le mythe de la démocratie raciale, une idéologie de l’harmonie raciale ayant longtemps dominé le paysage politique au Brésil. Selon ces auteurs, les telenovelas aident à démasquer le mythe à travers leurs représentations des inégalités et des problématiques vécues par les populations afro-descendantes. Le présent travail vise à étudier le thème de la démocratie raciale dans les telenovelas à travers une analyse de l’évolution des représentations qui y sont véhiculées et du statut social et politique des populations afro-brésiliennes, entre 1985 et 2015. Cette analyse permettra de démonter dans quelle mesure les feuilletons reflètent les conditions sociopolitiques des populations afro-brésiliennes, et s’ils reproduisent les principes du mythe de la démocratie raciale, soit une vision harmonieuse de la société brésilienne.
Leveraging Context to Support Automated Food Recognition in Restaurants
Creators: name: Bettadapura, Vinay
name: Thomaz, Edison
name: Parnami, Aman
name: Abowd, Gregory
name: Essa, Irfan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The pervasiveness of mobile cameras has resulted in a dramatic increase in food photos, which are pictures reflecting what people eat. In this paper, we study how taking pictures of what we eat in restaurants can be used for the purpose of automating food journaling. We propose to leverage the context of where the picture was taken, with additional information about the restaurant, available online, coupled with state-of-the-art computer vision techniques to recognize the food being consumed. To this end, we demonstrate image-based recognition of foods eaten in restaurants by training a classifier with images from restaurant's online menu databases. We evaluate the performance of our system in unconstrained, real-world settings with food images taken in 10 restaurants across 5 different types of food (American, Indian, Italian, Mexican and Thai).
description: 8 pages in Proceedings of the 2015 IEEE Winter Conference on Applications of Computer Vision (WACV 2015)
Consensus, Cohesion and Connectivity
Creators: name: Bruggeman, Jeroen
Publisher: name: arXiv
Year: 2016
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Social life clusters into groups held together by ties that also transmit information. When collective problems occur, group members use their ties to discuss what to do and to establish an agreement, to be reached quick enough to prevent discounting the value of the group decision. The speed at which a group reaches consensus can be predicted by the algebraic connectivity of the network, which also imposes a lower bound on the group's cohesion. This specific measure of connectivity is put to the test by re-using experimental data, which confirm the prediction.
Glyoxalase 1 Attenuates the Effects of Chronic Hyperglycemia on Explant-Derived Cardiac Stem Cells
Creators: name: Villanueva, Melanie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Diabetes mellitus
Explant-derived cardiac stem cell
Glyoxalase 1
Heart failure

description: Given that chronic hyperglycemia generates toxic methylglyoxal, the detoxifying effect of glyoxalase-1 (Glo1) on chronic hyperglycemia induced explant-derived cardiac stem cell (EDC) dysfunction was investigated. Wildtype (WT) and Glo1 over-expressing (Glo1TG) mice with or without streptozotocin treatment were studied. Hyperglycemia reduced overall culture yields while increasing the reactive dicarbonyl content within WT mice. These intrinsic cell changes reduced the angiogenic potential and nanoparticle production by hyperglycemic EDCs while promoting cell senescence. Compared to transplant of normoglycemic WT EDCs, hyperglycemic EDCs reduced myocardial function following infarction by inhibiting angiogenesis and endogenous repair mechanisms. In contrast, EDCs from hyperglycemic Glo1TG mice decreased reactive dicarbonyl content and restored culture yields. Intramyocardial injection of hyperglycemic Glo1TG EDCs also boosted myocardial function and reduced scarring. These findings demonstrate that, while chronic hyperglycemia decreases the regenerative performance of EDCs, over-expression of Glo1 reduces dicarbonyl stress and rescues the adverse effects of hyperglycemia on EDCs.
Forward-backward correlations with strange particles in PYTHIA
Creators: name: Altsybeev, Igor
name: Feofilov, Grigory
name: Gillies, Ewen Lawson
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present studies of strange particle yields and correlations in $pp$ collisions in the PYTHIA8 event generator by studying forward-backward correlations. Several key processes that give rise to these correlative effects are identified and manipulated to probe the fundamental properties of strange particle emitting sources. The sensitivity of strange particle production and correlations to PYTHIA's multiparton interaction, color reconnection, and explicit strangeness suppression are shown.
description: To be published in Proceedings of Strangeness in Quark Matter Conference, SQM 2015 Dubna
Experimental quantum state engineering with time-separated heraldings from a continuous-wave light source: a temporal-mode analysis
Creators: name: Huang, K.
name: Jeannic, H. Le
name: Verma, V. B.
name: Shaw, M. D.
name: Marsili, F.
name: Nam, S. W.
name: Wu, E
name: Zeng, H.
name: Morin, O.
name: Laurat, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Conditional preparation is a well-established technique for quantum state engineering of light. A general trend is to increase the number of heralding detection events in such realization to reach larger photon-number states or their arbitrary superpositions. In contrast to pulsed implementations, where detections only occur within the pulse window, for continuous-wave light the temporal separation of the conditioning detections is an additional degree of freedom and a critical parameter. Based on the theoretical study by A.E.B. Nielsen and K. Molmer and on a continuous-wave two-mode squeezed vacuum from a nondegenerate optical parametric oscillator, we experimentally investigate the generation of two-photon state with tunable delay between the heralding events. The present work illustrates the temporal multimode features in play for conditional state generation based on continuous-wave light sources.
Optimizing the interRAI assessment tool in care planning processes for long-term care residents: A scoping review protocol
Creators: name: Iduye, Steve
name: Risling, Tracie
name: McKibbon, Shelley
name: Iduye, Damilola
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences

description: Objective: In this scoping review, the objective is to chart and report on existing literature regarding how the interRAI assessment tool drives care planning processes for residents in long-term care settings. Introduction: Before COVID 19 pandemic in Canada, there were discussions among care providers and long-term care residents and their care representatives regarding how to improve the quality of care through the use of international resident assessment instruments (interRAI) in long-term care facilities. As many provinces and territories have deployed this digital tool, the provision of quality care in long-term care (LTC) for consistent health outcomes for the residents is still unattainable. Inclusion criteria: This review will incorporate all studies on the use of interRAI in care planning processes for residents aged 65 years and over, in long-term care facilities. English language publications will be an inclusion factor. Excluded from the review are other interRAI assessment suites. Methods: The Joanna Briggs Institute methodology employed includes a three-step search strategy to i) identify keywords from the Cumulated Index of Nursing and Allied Health Literature, ii) conduct a comprehensive search using all of the initial and related keywords found across other selected databases, and iii) screen the titles and abstracts and the full texts review of the articles against the inclusion criteria by two independent reviewers. Extracted data will be presented in a tabular form with a narrative that addresses the review objective. Keywords: interRAI; standardized data; long-term care; care planning
Tuning the van der Waals Interaction of Graphene with Molecules via Doping
Creators: name: Huttmann, Felix
name: Martínez-Galera, Antonio J.
name: Caciuc, Vasile
name: Atodiresei, Nicolae
name: Schumacher, Stefan
name: Standop, Sebastian
name: Hamada, Ikutaro
name: Wehling, Tim O.
name: Blügel, Stefan
name: Michely, Thomas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We use scanning tunneling microscopy to visualize and thermal desorption spectroscopy to quantitatively measure that the binding of naphthalene molecules to graphene (Gr), a case of pure van der Waals (vdW) interaction, strengthens with $n$- and weakens with $p$-doping of Gr. Density functional theory calculations that include the vdW interaction in a seamless, ab initio way accurately reproduce the observed trend in binding energies. Based on a model calculation, we propose that the vdW interaction is modified by changing the spatial extent of Gr's $π$ orbitals via doping.
The Degradation of Synthetic Polymeric Scaffolds With Strut-like Architecture Influences the Mechanics-dependent Repair Process of an Osteochondral Defect in Silico
Creators: name: Tortorici, Martina
name: Petersen, Ansgar
name: Duda, Georg N.
name: Checa, Sara
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: osteochondral defect
subject: tissue engineering
subject: scaffold degradation
subject: computer model
subject: mechanobiolgy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Current clinical treatments of osteochondral defects in articulating joints are frequently not successful in restoring articular surfaces. Novel scaffold-based tissue engineering strategies may help to improve current treatment options and foster a true regeneration of articulating structures. A frequently desired property of scaffolds is their ability to degrade over time and allow a full restoration of tissue and function. However, it remains largely unknown how scaffold degradation influences the mechanical stability of the tissue in a defect region and, in turn, the regenerative process. Such differing goals-supporting regeneration by degrading its own structure-can hardly be analyzed for tissue engineered constructs in clinical trials and in vivo preclinical experiments. Using an in silico analysis, we investigated the degradation-induced modifications in material and architectural properties of a scaffold with strut-like architecture over the healing course and their influence on the mechanics-dependent tissue formation in osteochondral defects. The repair outcome greatly varied depending on the degradation modality, i.e. surface erosion or bulk degradation with and without autocatalysis, and of the degradation speed, i.e. faster, equal or slower than the expected repair time. Bulk degradation with autocatalysis, independently of degradation speed, caused the mechanical failure of the scaffold prior to osteochondral defect repair and was thereby deemed inappropriate for further application. On the other hand, scaffolds with strut-like architecture degrading by both surface erosion and bulk degradation with slow degradation speed resulted in comparably good repair outcomes, thereby indicating such degradation modalities as favorable for the application in osteochondral defects.
Materials Data Platform: a constellation of systems to promote materials data-oriented science
Creators: name: 松田 朝彦
name: 門平 卓也
name: 吉川 英樹
name: 石井 真史
name: 出村 雅彦
name: 谷藤 幹子
Publisher: name: NIMS
Year: 2019
Subjects: Research data management
Materials data platform
Data-oriented science
Database
Materials digital transform
Metadata
Materials informatics

description: A constellation of research data systems is being developed, to boost a more data-oriented approach to materials science. Four main functionalities were identified as what such a platform should provide: data generation, storage, utilization, and publication of materials data. On this platform, different systems provide specific functionalities as micro-systems, and are being integrated together to allow materials data to flow. This poster will cover the overview of the whole platform, the system to allow efficient aggregation, and tools for automatic conversion of measurement data. Challenges and measures being taken to ensure secure and trustworthy operation of the platform will also be covered.
Measuring COVID-19-related fear and threat in Australian, Indian, and Nepali university students
Creators: name: Collins, Francesca
Publisher: name: Monash University
Year: 2023
Subjects: Other education not elsewhere classified
Personality and individual differences

description: The present study describes the adaption and validation of a brief measure of contagion-related fear and threat in Australian, Indian, and Nepali university students in Australia at the height of the first wave of the COVID-19 pandemic. Adapted from Ho, Kwong-Lo, Mak, and Wong’s (2005) SARS-related fear scale, the Contagion Fear and Threat Scale (CFTS) was rapidly adapted to capture the experience of COVID-19 pandemic-related fear. The factor structure and validity of the 6-item scale were established among Australian (n = 154), Indian (n = 111), and Nepali (n = 149) university students studying in Australia in May–June 2020. Factor analysis revealed two 3- item factors in the Australian student sample: Fear of Infection and Existential Threat. These factors were confirmed in the Indian and Nepali student samples and mirror those found by the Ho et al. (2005) in their original instrument. The convergent and discriminant validity of the full CFTS, Fear of Infection, and Existential Threat scales are indicated via correlations with established measures of depression, anxiety, stress, subjective wellbeing, and religiosity. Differences in the performance of the Fear of Infection and Existential Threat scales are considered in terms of the respective objective and subjective nature of the constructs
Use Of Fertilizers In England And Wales, 1987, Rothamsted Experimental Station Report for 1987
Creators: name: J. I. Elsmere
Publisher: name: Lawes Agricultural Trust
Year: 1988
Subjects: subject: rothamsted research

description: Scanned PDF of Use Of Fertilizers In England And Wales, 1987, part of Rothamsted Experimental Station Report for 1987
Nationalism in an International Movement: Polish Art Nouveau, 1890-1910
Creators: name: Marchman, Hannah Justine
Publisher: name: University of North Carolina at Chapel Hill
Year: 2012

description: While the Art Nouveau movement in Europe has been extensively studied, Polish art has been largely left out of the discussion. However, this absence should not be considered as proof that Polish artists did not create art works in the Art Nouveau style. In fact, Art Nouveau was prevalent in Poland, but unlike the movement in Europe, Polish Art Nouveau tended to have political undertones. This thesis examines how Polish artists adapted the wider Art Nouveau movement to Polish culture, and assisted the political agenda that Polish art had been charged with in the aftermath of the eighteenth century partitions. Furthermore, this thesis describes the wider Polish Art Nouveau movement and looks at the underlying meanings of paintings, stained glass window designs, posters, and postcards from 1890 to 1910.
Optic chiasm measurements may be useful markers of anterior optic pathway degeneration in neuromyelitis optica spectrum disorders
Creators: name: Juenger, Valentin
name: Cooper, Graham
name: Chien, Claudia
name: Chikermane, Meera
name: Oertel, Frederike Cosima
name: Zimmermann, Hanna
name: Ruprecht, Klemens
name: Jarius, Sven
name: Siebert, Nadja
name: Kuchling, Joseph
name: Papadopoulou, Athina
name: Asseyer, Susanna
name: Bellmann-Strobl, Judith
name: Paul, Friedemann
name: Brandt, Alexander U.
name: Scheel, Michael
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Optic neuritis
subject: Optic chiasm
subject: Magnetic resonance imaging
subject: Neuromyelitis optica
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objectives: We aimed to evaluate optic chiasm (OC) measures as potential imaging marker for anterior optic pathway damage assessment in the context of neuromyelitis optica spectrum disorders (NMOSD). Materials and method: This cross-sectional study included 39 patients exclusively with aquaporin 4-IgG seropositive NMOSD of which 25 patients had a history of optic neuritis (NMOSD-ON) and 37 age- and sex-matched healthy controls (HC). OC heights, width, and area were measured using standard 3D T1-weighted MRI. Sensitivity of these measures to detect neurodegeneration in the anterior optic pathway was assessed in receiver operating characteristics analyses. Correlation coefficients were used to assess associations with structural measures of the anterior optic pathway (optic nerve dimensions, retinal ganglion cell loss) and clinical measures (visual function and disease duration). Results: OC heights and area were significantly smaller in NMOSD-ON compared to HC (NMOSD-ON vs. HC p < 0.0001). An OC area smaller than 22.5 mm2 yielded a sensitivity of 0.92 and a specificity of 0.92 in separating chiasms of NMOSD-ON from HC. OC area correlated well with structural and clinical measures in NMOSD-ON: optic nerve diameter (r = 0.4, p = 0.047), peripapillary retinal nerve fiber layer thickness (r = 0.59, p = 0.003), global visual acuity (r = - 0.57, p = 0.013), and diseases duration (r = - 0.5, p = 0.012). Conclusion: Our results suggest that OC measures are promising and easily accessible imaging markers for the assessment of anterior optic pathway damage.
Effectiveness of the clinical decision support tool ESR eGUIDE for teaching medical students the appropriate selection of imaging tests: randomized cross-over evaluation
Creators: name: Diekhoff, Torsten
name: Kainberger, Franz
name: Oleaga, Laura
name: Dewey, Marc
name: Zimmermann, Elke
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Random allocation
subject: Clinical decision support systems
subject: Diagnostic imaging
subject: Learning
subject: Medical students
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objectives: To evaluate ESR eGUIDE-the European Society of Radiology (ESR) e-Learning tool for appropriate use of diagnostic imaging modalities-for learning purposes in different clinical scenarios. Methods: This anonymized evaluation was performed after approval of ESR Education on Demand leadership. Forty clinical scenarios were developed in which at least one imaging modality was clinically most appropriate, and the scenarios were divided into sets 1 and 2. These sets were provided to medical students randomly assigned to group A or B to select the most appropriate imaging test for each scenario. Statistical comparisons were made within and across groups. Results: Overall, 40 medical students participated, and 31 medical students (78%) answered both sets. The number of correctly chosen imaging methods per set in these 31 paired samples was significantly higher when answered with versus without use of ESR eGUIDE (13.7 ± 2.6 questions vs. 12.1 ± 3.2, p = 0.012). Among the students in group A, who first answered set 1 without ESR eGUIDE (11.1 ± 3.2), there was significant improvement when set 2 was answered with ESR eGUIDE (14.3 ± 2.5, p = 0.013). The number of correct answers in group B did not drop when set 2 was answered without ESR eGUIDE (12.4 ± 2.6) after having answered set 1 first with ESR eGUIDE (13.0 ± 2.7, p = 0.66). Conclusion: The clinical decision support tool ESR eGUIDE is suitable for training medical students in choosing the best radiological imaging modality in typical scenarios, and its use in teaching radiology can thus be recommended. Key points: • ESR eGUIDE improved the number of appropriately selected imaging modalities among medical students. • This improvement was also seen in the group of students which first selected imaging tests without ESR eGUIDE. • In the student group which used ESR eGUIDE first, appropriate selection remained stable even without the teaching tool.
Modified vertex Folkman numbers
Creators: name: Bikov, Aleksandar
name: Nenov, Nedyalko
Publisher: name: arXiv
Year: 2015
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Let $a_1, ..., a_s$ be positive integers. For a graph $G$ the expression $$ G \overset{v}{\rightarrow} (a_1, ..., a_s) $$ means that for every coloring of the vertices of $G$ in $s$ colors ($s$-coloring) there exists $i \in \{1, ..., s\}$, such that there is a monochromatic $a_i$-clique of color $i$. If $m$ and $p$ are positive integers, then $$ G \overset{v}{\rightarrow} {m}\big\vert_{p} $$ means that for arbitrary positive integers $a_1, ..., a_s$ ($s$ is not fixed), such that $\sum_{i = 1}^{s}(a_i - 1) + 1 = m$ an $\max{\{a_1, ..., a_s\}} \leq p$ we have $G \overset{v}{\rightarrow} (a_1, ..., a_s)$. Let $$ \widetilde{\mathcal{H}}({m}\big\vert_{p}; q) = \{G : G \overset{v}{\rightarrow} {m}\big\vert_{p} \mbox{ and } ω(G) < q\}. $$ The modified vertex Folkman numbers are defined by the equality $$ \widetilde{F}({m}\big\vert_{p}; q) = \min{\{|V(G)| : G \in \widetilde{\mathcal{H}}({m}\big\vert_{p}; q)\}}. $$ If $q \geq m$ these numbers are known and they are easy to compute. In the case $q = m - 1$ we know all of the numbers when $p \leq 5$. In this work we consider the next unknown case $p = 6$ and we prove with the help of a computer that $$ \widetilde{F}({m}\big\vert_{6}; m - 1) = m + 10. $$
COVID-19 Patients Require Prolonged Extracorporeal Membrane Oxygenation Support for Survival Compared With Non-COVID-19 Patients
Creators: name: Russ, Martin
name: Menk, Mario
name: Graw, Jan Adriaan
name: Skrypnikov, Vladimir
name: Hunsicker, Oliver
name: Rudat, Kathleen
name: Weber-Carstens, Steffen
name: Francis, Roland C. E.
name: Pickerodt, Philipp A.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: COVID-19
subject: duration of extracorporeal membrane oxygenation therapy
subject: extracorporeal membrane oxygenation survival
subject: pulmonary fibrotic remodeling
subject: venovenous extracorporeal membrane oxygenation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: OBJECTIVES: To investigate the ICU survival of venovenous extracorporeal membrane oxygenation (ECMO) patients suffering from COVID-19–related acute respiratory distress syndrome (ARDS) versus ECMO patients without COVID-19 (non-COVID-19)–related ARDS. DESIGN: Preliminary analysis of data from two prospective ECMO trials and retrospective analysis of a cohort of ARDS ECMO patients. SETTING: Single-center ICU. PATIENTS: Adult ARDS ECMO patients, 16 COVID-19 versus 23 non-COVID-19 patients. Analysis of retrospective data from 346 adult ARDS ECMO patients. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: COVID-19 and non-COVID-19 ARDS patients did not differ with respect to preexisting disease or body mass index. ICU survival rate was 62% for COVID-19 ECMO patients and 70% for non-COVID-19 ECMO patients. COVID-19 ECMO survivors were supported with ECMO for a median of 43 days (interquartile range [IQR], 18–58 d) versus 16 days (IQR, 19–39 d; p = 0.03) for non-COVID-19 patients. The median duration of ECMO therapy for all ARDS patients between 2007 and 2018 was 15 days (IQR, 6–28 d). The subgroup of patients suffering from any viral pneumonia received ECMO support for a median of 16 days (IQR, 9–27 d), survivors of influenza pneumonia received ECMO support for 13 days (IQR, 7–25 d). CONCLUSIONS: COVID-19 patients required significant longer ECMO support compared with patients without COVID-19 to achieve successful ECMO weaning and ICU survival.
PHYSIOLOGY OF GRAIN YIELD OF WHEAT AND BARLEY, Rothamsted Experimental Station Report for 1973 Part 2
Creators: name: GILLIAN N. THORNE
Publisher: name: Lawes Agricultural Trust
Year: 1974
Subjects: subject: rothamsted research
subject: crop yield
subject: Rothamsted ley-arable rotation experiment

description: Scanned PDF of PHYSIOLOGY OF GRAIN YIELD OF WHEAT AND BARLEY, part of Rothamsted Experimental Station Report for 1973 Part 2
Fighting the social media wildfire: how crisis communication must adapt to prevent from fanning the flames
Creators: name: Soule, Allison R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: When a nine-month correspondence seeking reparations for musical instruments damaged by United Airlines employees stalemated, Canadian musician Dave Carroll took action online. Utilizing the video-sharing Web site YouTube, Carroll narrated his ordeal through the lyrics of a music video entitled United Breaks Guitars. Within hours, the video went viral generating a torrent of negative YouTube comments about United, commentary from the mainstream media, and more than 3 million views the first week of its launch. United Breaks Guitars embodies the new phenomenon of a social media wildfire in which the rapid proliferation of information through social media causes severe reputational damage to organizations whose crisis communication plans are ill equipped to handle online dilemmas. Using symbolic interactionist theory, this case analysis explores the phenomenon in detail and provides suggestions for how organizations must re-evaluate existing crisis communication plans to respond effectively to an online audience in the billions.