cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Variational Autoencoders for Cancer Data Integration: Design Principles and Computational Practice.
Creators: name: Simidjievski, Nikola
name: Bodnar, Cristian
name: Tariq, Ifrah
name: Scherer, Paul
name: Andres Terre, Helena
name: Shams, Zohreh
name: Jamnik, Mateja
name: Liò, Pietro
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Artificial intelligence
Machine Learning
Deep Learning
Multi-omic Analysis
Variational Autoencoder
Bioinformactics
Cancer–breast Cancer
Integrative Data Analyses

description: International initiatives such as the Molecular Taxonomy of Breast Cancer International Consortium are collecting multiple data sets at different genome-scales with the aim to identify novel cancer bio-markers and predict patient survival. To analyze such data, several machine learning, bioinformatics, and statistical methods have been applied, among them neural networks such as autoencoders. Although these models provide a good statistical learning framework to analyze multi-omic and/or clinical data, there is a distinct lack of work on how to integrate diverse patient data and identify the optimal design best suited to the available data.In this paper, we investigate several autoencoder architectures that integrate a variety of cancer patient data types (e.g., multi-omics and clinical data). We perform extensive analyses of these approaches and provide a clear methodological and computational framework for designing systems that enable clinicians to investigate cancer traits and translate the results into clinical applications. We demonstrate how these networks can be designed, built, and, in particular, applied to tasks of integrative analyses of heterogeneous breast cancer data. The results show that these approaches yield relevant data representations that, in turn, lead to accurate and stable diagnosis.
title: 03_0521
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Therapeutic and Mechanistic Perspectives of Protein Complexes in Breast Cancer.
Creators: name: Waterhouse, Mark P
name: Ugur, Rosie
name: Khaled, Walid T
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Transcription factor
Protein complexes
Breast cancer
Protein-protein interaction
Cancer therapy
Post-translational modification
Protac
Tnbc

description: Breast cancer affects one in eight women making it the most common cancer in the United Kingdom, accounting for 15% of all new cancer cases. One of the main challenges in treating breast cancer is the heterogeneous nature of the disease. At present, targeted therapies are available for hormone receptor- and HER2-positive tumors. However, no targeted therapies are currently available for patients with triple negative breast cancer (TNBC). This likely contributes to the poor prognostic outcome for TNBC patients. Consequently, there is a clear clinical need for the development of novel drugs that efficiently target TNBC. Extensive genomic and transcriptomic characterization of TNBC has in recent years identified a plethora of putative oncogenes. However, these driver oncogenes are often critical in other cell types and/or transcription factors making them very difficult to target directly. Therefore, other approaches may be required for developing novel therapeutics that fully exploit the specific functions of TNBC oncogenes in tumor cells. Here, we will argue that more research is needed to identify the protein-protein interactions of TNBC oncogenes as a means for (a) mechanistically understanding the biological function of these oncogenes in TNBC and (b) providing novel therapeutic targets that can be exploited for selectively inhibiting the oncogenic roles of TNBC oncogenes in cancer cells, whilst sparing normal healthy cells.
Sialyl Lewis X - Molecule of the Month November 1996 [Archived version]
Creators: name: Isles, Stephen J
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for November 1996 about Sialyl Lewis X. It is a pdf archive version of the HTML webpage.
Interface Engineered Room-Temperature Ferromagnetic Insulating State in Ultrathin Manganite Films.
Creators: name: Li, Weiwei
name: Zhu, Bonan
name: He, Qian
name: Borisevich, Albina Y
name: Yun, Chao
name: Wu, Rui
name: Lu, Ping
name: Qi, Zhimin
name: Wang, Qiang
name: Chen, Aiping
name: Wang, Haiyan
name: Cavill, Stuart A
name: Zhang, Kelvin H L
name: MacManus-Driscoll, Judith L
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Interface Engineering
Ferromagnetic Insulators
Manganite Thin Films
Abo3 Perovskite Oxides
Octahedral Proximity Effect

description: Ultrathin epitaxial films of ferromagnetic insulators (FMIs) with Curie temperatures near room temperature are critically needed for use in dissipationless quantum computation and spintronic devices. However, such materials are extremely rare. Here, a room-temperature FMI is achieved in ultrathin La0.9Ba0.1MnO3 films grown on SrTiO3 substrates via an interface proximity effect. Detailed scanning transmission electron microscopy images clearly demonstrate that MnO6 octahedral rotations in La0.9Ba0.1MnO3 close to the interface are strongly suppressed. As determined from in situ X-ray photoemission spectroscopy, O K-edge X-ray absorption spectroscopy, and density functional theory, the realization of the FMI state arises from a reduction of Mn eg bandwidth caused by the quenched MnO6 octahedral rotations. The emerging FMI state in La0.9Ba0.1MnO3 together with necessary coherent interface achieved with the perovskite substrate gives very high potential for future high performance electronic devices.
Water - Molecule of the Month October 1996 [Archived version]
Creators: name: Kenner, Shawn Huston
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for October 1996 about water. It is a pdf archive version of the HTML webpage.
title: 01_2412
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Number of days required to estimate physical activity constructs objectively measured in different age groups: Findings from three Brazilian (Pelotas) population-based birth cohorts.
Creators: name: Ricardo, Luiza Isnardi Cardoso
name: Wendt, Andrea
name: Galliano, Leony Morgana
name: De Andrade Muller, Werner
name: Niño Cruz, Gloria Izabel
name: Wehrmeister, Fernando
name: Brage, Soren
name: Ekelund, Ulf
name: Crochemore M Silva, Inácio
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020

description: PURPOSE:The present study aims to estimate the minimum number of accelerometer measurement days needed to estimate habitual physical activity (PA) among 6- (2010), 18- (2011) and 30- (2012) year-old participants, belonging to three population-based Brazilian birth cohorts. METHOD:PA was assessed by triaxial wrist-worn GENEActiv accelerometers and the present analysis is restricted to participants with at least 6 consecutive days of measurement. Accelerometer raw data were analyzed with R-package GGIR. Description of PA measures (overall PA, moderate-to-vigorous PA (MVPA), light PA (LPA)) on weekdays and weekend days were conducted, and statistical differences were tested with chi-squared and Kruskal-Wallis tests. Spearman Brown Formulae was applied to test reliability of different number of days of accelerometer use. RESULTS:Differences between week and weekend days regarding LPA, MVPA and overall PA, were only observed among 30-year-olds. Higher levels of MVPA (p = 0.006) and overall PA (p<0.001) were identified on weekdays. For overall PA, to achieve a reliability coefficient >0.70, two and three days of measurement were needed in adults and children, respectively. For LPA, a reliability coefficient >0.70 was achieved with five days in 6-year-old children, three days in 18-year-old young adults, and four days in 30-year-old adults. Considering MVPA, four days would be necessary to represent a week of measurement among all cohort groups. CONCLUSION:Our results show that four and five measurement days are needed to estimate all habitual PA constructs, for children and adults, respectively. Also, among 30-year-old adults, it is important to make efforts towards weekend days measurement.
The Earth BioGenome Project 2020: Starting the clock
Creators: name: Lewin, HA
name: Richards, S
name: Aiden, E Lieberman
name: Allende, ML
name: Archibald, JM
name: Bálint, M
name: Barker, KB
name: Baumgartner, B
name: Belov, K
name: Bertorelle, G
name: Blaxter, ML
name: Cai, J
name: Caperello, ND
name: Carlson, K
name: Castilla-Rubio, JC
name: Chaw, SM
name: Chen, L
name: Childers, AK
name: Coddington, JA
name: Conde, DA
name: Corominas, M
name: Crandall, KA
name: Crawford, AJ
name: DiPalma, F
name: Durbin, R
name: Ebenezer, TGE
name: Edwards, SV
name: Fedrigo, O
name: Flicek, P
name: Formenti, G
name: Gibbs, RA
name: Gilbert, MTP
name: Goldstein, MM
name: Graves, Jennifer
name: Greely, HT
name: Grigoriev, IV
name: Hackett, KJ
name: Hall, N
name: Haussler, D
name: Helgen, KM
name: Hogg, CJ
name: Isobe, S
name: Jakobsen, KS
name: Janke, A
name: Jarvis, ED
name: Johnson, WE
name: Jones, SJM
name: Karlsson, EK
name: Kersey, PJ
name: Kim, JH
name: Kress, WJ
name: Kuraku, S
name: Lawniczak, MKN
name: Leebens-Mack, JH
name: Li, X
name: Lindblad-Toh, K
name: Liu, X
name: Lopez, JV
name: Marques-Bonet, T
name: Mazard, S
name: Mazet, JAK
name: Mazzoni, CJ
name: Myers, EW
name: O'Neill, RJ
name: Paez, S
name: Park, H
name: Robinson, GE
name: Roquet, C
name: Ryder, OA
name: Sabir, JSM
name: Shaffer, HB
name: Shank, TM
name: Sherkow, JS
name: Soltis, PS
name: Tang, B
name: Tedersoo, L
name: Uliano-Silva, M
name: Wang, K
name: Wei, X
name: Wetzer, R
name: Wilson, JL
name: Xu, X
name: Yang, H
name: Yoder, AD
name: Zhang, G
Publisher: name: La Trobe
Year: 2022

description: No description supplied
Generic identification and classification of morphostructures in the Noachis-Sabaea region, southern highlands of Mars
Creators: name: Trishit Ruj
name: Komatsu, Goro
name: Dohm, James M.
name: Hirdy Miyamoto
name: Salese, Francesco
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Computational Biology

description: The Noachis-Sabaea region in the southern highlands preserves some of the oldest Martian crust. It records deformation by both endogenic and exogenic processes. This deformation includes giant impacts and their impact stresses, which could have resulted in both the reactivation and modification of pre-impact tectonic structures, in addition to impact-generated tectonic structures. There are also widespread extensional and compressional tectonic structures, which were formed due to endogenic processes. We have produced the first detailed morphostructural map of the Noachis-Sabaea region, which details the characteristics and spatial arrangements of structures in the region, forms the basis for making inferences about Noachian-Hesperian crustal activity, and provides information for further studies regarding the reconstruction of the evolutional history of the region.
Vancomycin - Molecule of the Month July 1997 [Archived version]
Creators: name: Bunch, Alan
name: Baines, Anthony
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for July 1997 about vancomycin. It is a pdf archive version of the HTML webpage.
N2S2 - Molecule of the Month October 1997 [Archived version]
Creators: name: May, Paul
name: Gerratt, Joe
name: S.J. McNicholas
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for October 1997 about N2S2. It is a pdf archive version of the HTML webpage.
How Status Conflict Undermines Athletes' Willingness to Help New Teammates
Creators: name: Boroumand, Suzanne
name: Eys, Mark
name: Benson, Alex J.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Drawing from theory on social hierarchy and intragroup behaviors, the current study examined whether status conflicts attenuate willingness to help newcomers. Using experimental vignettes with high-level team sport athletes (N = 112), the results demonstrated that athletes were less willing to help high-status newcomers who played the same position than newcomers who played (a) a different position and (b) the same position but were described to be lower status. Our findings show that when positional competition creates a salient status threat, this can curtail an athlete's willingness to help in the socialization processes of a teammate.
MCM-41 - Molecule of the Month April 1998 [Archived version]
Creators: name: Gusev, Vladimir
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for April 1998 about MCM-41. It is a pdf archive version of the HTML webpage.
title: 01_1064
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Sulfanilamide - Molecule of the Month February 1998 [Archived version]
Creators: name: Tebbutt, Peter
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for February 1998 about sulfanilamide. It is a pdf archive version of the HTML webpage.
Schüler*innen wiederholen selbstständig lineare Funktionen
Creators: name: Hamers, Philipp
name: Bekel-Kastrup, Holger
name: Kleinert, Svea Isabel
name: Tegtmeier, Nina
name: Wilde, Matthias
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht.
Year: 2020

description: In dem Forschungsprojekt „Bielefelder Binnendifferenzierung in den MINT-Fächern“ (BiBi-MINT) am Oberstufen-Kolleg Bielefeld zur Verzahnung von Mathematikunterricht und Naturwissenschaftsunterricht mit gleichzeitiger Binnendifferenzierung sind unter anderem zwei gestufte Lernhilfen zur Wiederholung linearer Funktionen entstanden und evaluiert worden. Sie sind dazu geeignet, dass Schüler*innen eigenverantwortlich lineare Funktionen wiederholen und vertiefen und können ebenfalls als exemplarisches Beispiel in der Lehrer*innenbildung dienen.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht., Bd. 2 Nr. 1 (2020): Die Materialwerkstatt - Ausgabe 2
Multi-omics data analysis in the cloud: inference of differential breast cancer-related network hubs between TCGA patient cohorts.
Creators: name: Kawther Abdilleh
name: Aguilar, Boris
name: Taylor, Ronald
name: Acquaah-Mensah, George
Publisher: name: F1000 Research Limited
Year: 2020

description: Among women, breast invasive carcinoma (BrCA) remains a leading cause of mortality. The Cancer Genome Atlas (TGCA) is a comprehensive repository data derived from samples of cancer patients. Earlier work indicates prognosis tends to be worse for Black/ African-American stage II breast invasive carcinoma patients diagnosed at age 50 years or younger (B/AA50), compared to White patients of similar age (W50). In this work, data from BrCA patients were further interrogated for factors driving differences in gene expression regulation patterns between the two cohorts.
Wer bin ich?
Creators: name: Fränkel, Silvia
name: Sellmann-Risse, Daniela
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht.
Year: 2020

description: Artenkenntnis zu vermitteln ist im Kontext von Umweltbildung bedeutsam: So schützen Menschen besonders das, was sie kennen und lieben. Kinder interessieren sich sehr für Tiere in ihrem Lebensumfeld. Um dieses Interesse aufzugreifen, wird in diesem Beitrag ein Quiz beschrieben, bei welchem die Schüler*innen zwölf Tiere des heimischen Waldes mithilfe des Spielformates „Wer bin ich?“ erraten und so artspezifische Informationen lernen. Die spielerische Herangehensweise wirkt besonders motivierend und fördert so das Lernen.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht., Bd. 2 Nr. 1 (2020): Die Materialwerkstatt - Ausgabe 2
Fächerübergreifender Unterricht zwischen den Basiskursen Naturwissenschaften und Mathematik
Creators: name: Kleinert, Svea Isabel
name: Hamers, Philipp
name: Bekel-Kastrup, Holger
name: Haunhorst, Darius
name: Tegtmeier, Nina
name: Wilde, Matthias
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht.
Year: 2020

description: Das Forschungsprojekt BiBi-MINT am Oberstufen-Kol­leg Bielefeld („Bielefelder Binnendifferenzierung in den MINT-Fächern“) verfolgt das Ziel eines Fächerübergriffes zwischen dem Naturwissenschafts- und dem Mathematikunterricht. Schüler*innen sollen unterstützt werden, naturwissenschaftliche Phänomene mathematisch zu beschreiben und gleichzeitig mit anwendungsbezogenen naturwissenschaftlichen Kontexten im Mathematikunterricht zu arbeiten. Neben einer zeitlichen Verzahnung des Naturwissenschafts- und Mathematikunterrichts wird auf binnendifferenzierende Maßnahmen in Form von gestuften Lernhilfen zurückgegriffen. Dieser Beitrag führt somit ein fächerübergreifendes und binnendifferenzierendes Gesamtkonzept zwischen Naturwissenschafts- und Mathematikunterricht an, welches sowohl im schulischen Kontext als auch in der universitären Lehrer*innenbildung Anwendung finden kann.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht., Bd. 2 Nr. 1 (2020): Die Materialwerkstatt - Ausgabe 2
Undoing the Human: *Wild* Art and a Poetics of Ecology
Creators: name: Goodman, Andrew
Publisher: name: La Trobe
Year: 2022

description: The
contemporary turn towards ‘wildness’ and ‘rewilding’ seeks an intimacy and
bewilderment of subjecthood. While wildness as a western concept has very
problematic histories, in its reclaimed usage, Halberstam and Nyong’o argue
that it can also enact an ‘anarrangement’ of normalised boundaries and categories.
Gordon Pask’s 1957 chemical computing experiment that spontaneously grew an ear
in response to environmental stimulus poses similar questions about the
relational volition of matter, confronting not only the artist or scientist’s
control of their research, but the fundamentally colonial notion of a world
composed of discrete parts. This article engages with a critical reading of
Halberstam and Nyong’o’s writing to propose parallels between their conception
of the wild and the science of self-organisation, both of which engage in
aspects of decolonial critique through a troubling of the colonial mindset that
separates in order to maintain mastery. Pask’s experiment suggests the possibility
of alternative discourses and practices that emphasise an ethics of relation
through techniques of wilding.
Schüler*innen werten selbstständig ein Experiment zur Bestimmung der Zellsaftkonzentration (Osmose) aus
Creators: name: Bekel-Kastrup, Holger
name: Hamers, Philipp
name: Kleinert, Svea Isabel
name: Haunhorst, Darius
name: Wilde, Matthias
Publisher: name: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht.
Year: 2020

description: In dem Forschungsprojekt „Bielefelder Binnendifferenzierung in den MINT-Fächern“ (BiBi-MINT) am Oberstufen-Kolleg Bielefeld zur Verzahnung von Mathematikunterricht und Naturwissenschaftsunterricht mit gleichzeitigem Fokus auf die Binnendifferenzierung sind unter anderem gestufte Lernhilfen zur Auswertung eines Experimentes zur Bestimmung der Zellsaftkonzentration entwickelt, angewendet und evaluiert worden. Sie sind dazu geeignet, Schüler*innen eigenverantwortlich die Auswertung und Interpretation des Experimentes durchführen zu lassen. Das Untersuchungsprinzip des Experimentes ist das Bestimmen der Masse von Gemüsestreifen vor und nach dem Einlegen in verschieden konzentrierten NaCl-Lösungen. Die Lernhilfen beinhalten dabei sowohl eine wiederholende Hinführung zur Bestimmung der relativen Massendifferenz als auch eine mathematische Auswertung und Bestimmung der Zellsaftkonzentration. Zur Interpretation werden Inhalte der biologischen Unterrichtsreihe zur Osmose vermittelt bzw. wiederholend bearbeitet.
description: Die Materialwerkstatt. Zeitschrift für Konzepte und Arbeitsmaterialien für Lehrer*innenbildung und Unterricht., Bd. 2 Nr. 1 (2020): Die Materialwerkstatt - Ausgabe 2
Proline - Molecule of the Month May 1998 [Archived version]
Creators: name: Potter, Andrew
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for May 1998 about proline. It is a pdf archive version of the HTML webpage.
Associations of atopy and asthma during aging of an adult population over a 20-year follow-up
Creators: name: Diogenes S. Ferreira
name: Kaushik, Sonia
name: Smith, Catherine L.
name: Shyamali C. Dharmage
name: Geza P. Benke
name: Thompson, Bruce R.
name: E. Haydn Walters
name: Wolfe, Rory
name: Abramson, Michael J.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objective: Atopy is associated with asthma, but cross-sectional studies suggest this association may be weaker in older adults. It remains unclear if atopy predicts asthma later in adult life. We aimed to investigate whether atopy in young adults predicted asthma 20 years later and to quantify the contemporaneous relationship of atopy and asthma as adults age. Methods: Participants of the European Community Respiratory Health Survey (ECRHS) in Melbourne aged 20–44 years were followed for 20 years and completed questionnaires, skin prick tests (SPT) and allergen specific immunoglobulin E measurement at a baseline and two subsequent surveys. Using logistic regression and generalized estimating equations, we tested if atopy at baseline predicted current asthma later in life and estimated the association between current atopy measured at each survey and current asthma, while adjusting for potential confounders. Results: The analysis included 220 participants: 50.9% male. Mean (SD) age at baseline was 35.7 (5.7) years. Asthma and atopy prevalence remained stable over 20 years. Baseline atopy (SPT) was associated with current asthma (OR 9.74, 95%CI 4.22, 22.5) over 20 years, and current atopy (SPT) with concurrent asthma (3.12; 1.70, 5.74). Conclusions: Atopy remains strongly associated with current asthma in 40 to 64 year-old adults, both prospectively and contemporaneously, but the prospective association is stronger.
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0260
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0260, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0260, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Finasteride - Molecule of the Month August 1998 [Archived version]
Creators: name: Schieck, Cynthia L.
Publisher: name: figshare
Year: 2017
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: This is the Molecule of the Month entry for August 1998 about finasteride. It is a pdf archive version of the HTML webpage.
Assessing IQ in adolescents with mild to moderate cerebral palsy using the WISC-V
Creators: name: Coceski, M
name: Hocking, Darren
name: Reid, SM
name: Abu-Rayya, Hisham
name: Reddihough, DS
name: Wrennall, J
name: Stargatt, Robyn
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 320905
subject: Neurology and neuromuscular diseases
classificationCode: 520406
subject: Sensory processes, perception and performance
classificationCode: 520503
subject: Personality and individual differences

description: No description supplied.
Optimization of novel and greener approach for the coproduction of uricase and alkaline protease in Bacillus licheniformis by Box–Behnken model
Creators: name: Pawar, Shweta V.
name: Virendra K. Rathod
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry

description: This study explores a novel concept of coproduction of uricase and alkaline protease by Bacillus licheniformis using single substrate in single step. Seven local bacterial strains were screened for uricase production, amongst which B. licheniformis is found to produce highest uricase along with alkaline protease. Optimization of various factors influencing maximum enzyme coproduction by B. licheniformis is performed. Maximum enzyme productivity of 0.386 U/mL uricase and 0.507 U/mL alkaline protease is obtained at 8 hr of incubation period, 1% (v/v) inoculum, and at 0.2% (w/v) uric acid when the organism is cultivated at 25°C, 180 rpm, in a media containing xylose as a carbon source, urea as a nitrogen source, and initial pH of 9.5. The statistical experimental design method of Box–Behnken was further applied to obtain optimal concentration of significant parameters such as pH (9.5), uric acid concentration (0.1%), and urea concentration (0.05%). The maximum uricase and alkaline protease production by B. licheniformis using Box–Behnken design was 0.616 and 0.582 U/mL, respectively, with 1.6- and 1.13-fold increase as compared to one factor at a time optimized media. This study will be useful to develop an economic, commercially viable, and scalable process for simultaneous production of uricase and protease enzymes.
How Status Conflict Undermines Athletes’ Willingness to Help New Teammates
Creators: name: Boroumand, Suzanne
name: Benson, Alex J.
name: Eys, Mark
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Drawing from theory on social hierarchy and intragroup behaviors, the current study examined whether status conflicts attenuate willingness to help newcomers. Using experimental vignettes with high-level team sport athletes (N = 112), the results demonstrated that athletes were less willing to help high status newcomers who played the same position than newcomers who played (a) a different position and (b) the same position but were described to be lower status. Our findings show that when positional competition creates a salient status threat, this can curtail an athlete's willingness to help in the socialization processes of a teammate.
TSPAN6 is a suppressor of Ras-driven cancer
Creators: name: Humbert, Patrick
name: Pryjda, TZ
name: Pranjic, B
name: Farrell, A
name: Fujikura, K
name: de Matos Simoes, R
name: Karim, R
name: Kozieradzki, I
name: Cronin, SJF
name: Neely, GG
name: Meyer, TF
name: Hagelkruys, A
name: Richardson, Helena
name: Penninger, JM
Publisher: name: La Trobe
Year: 2022

description: Oncogenic mutations in the small GTPase RAS contribute to ~30% of human cancers. In a Drosophila genetic screen, we identified novel and evolutionary conserved cancer genes that affect Ras-driven tumorigenesis and metastasis in Drosophila including confirmation of the tetraspanin Tsp29Fb. However, it was not known whether the mammalian Tsp29Fb orthologue, TSPAN6, has any role in RAS-driven human epithelial tumors. Here we show that TSPAN6 suppressed tumor growth and metastatic dissemination of human RAS activating mutant pancreatic cancer xenografts. Whole-body knockout as well as tumor cell autonomous inactivation using floxed alleles of Tspan6 in mice enhanced KrasG12D-driven lung tumor initiation and malignant progression. Mechanistically, TSPAN6 binds to the EGFR and blocks EGFR-induced RAS activation. Moreover, we show that inactivation of TSPAN6 induces an epithelial-to-mesenchymal transition and inhibits cell migration in vitro and in vivo. Finally, low TSPAN6 expression correlates with poor prognosis of patients with lung and pancreatic cancers with mesenchymal morphology. Our results uncover TSPAN6 as a novel tumor suppressor receptor that controls epithelial cell identify and restrains RAS-driven epithelial cancer.
Associations Of Atopy And Asthma During Aging Of An Adult Population Over A 20-year Follow-up
Creators: name: Diogenes S. Ferreira
name: Kaushik, Sonia
name: Smith, Catherine L.
name: Shyamali C. Dharmage
name: Geza P. Benke
name: Thompson, Bruce R.
name: E. Haydn Walters
name: Wolfe, Rory
name: Abramson, Michael J.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objective: Atopy is associated with asthma, but cross-sectional studies suggest this association may be weaker in older adults. It remains unclear if atopy predicts asthma later in adult life. We aimed to investigate whether atopy in young adults predicted asthma 20 years later and to quantify the contemporaneous relationship of atopy and asthma as adults age. Methods: Participants of the European Community Respiratory Health Survey (ECRHS) in [city; data removed for double-blind peer review] aged 20–44 years were followed for 20 years and completed questionnaires, skin prick tests (SPT) and allergen specific immunoglobulin E measurement at a baseline and two subsequent surveys. Using logistic regression and generalized estimating equations, we tested if atopy at baseline predicted current asthma later in life and estimated the association between current atopy measured at each survey and current asthma, while adjusting for potential confounders. Results: The analysis included 220 participants: 50.9% male. Mean (SD) age at baseline was 35.7 (5.7) years. Asthma and atopy prevalence remained stable over 20 years. Baseline atopy (SPT) was associated with current asthma (OR 9.74, 95%CI 4.22, 22.5) over 20 years, and current atopy (SPT) with concurrent asthma (3.12; 1.70, 5.74). Conclusions: Atopy remains strongly associated with current asthma in 40 to 64 year-old adults, both prospectively and contemporaneously, but the prospective association is stronger.
Probing the influence of SIBLING proteins on collagen-I fibrillogenesis and denaturation
Creators: name: Chengyu Jiang
name: Zurick, Kevin
name: Chunlin Qin
name: Bernards, Matthew T.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Bone tissue is comprised of collagen, non-collagenous proteins, and hydroxyapatite and the SIBLING (small integrin binding, N-linked glycoprotein) family of proteins is the primary group of non-collagenous proteins. By replicating the native interactions between collagen and the SIBLING proteins at the interface of an implant, it is believed that a bone scaffold will more easily integrate with the surrounding tissue. In this work, bone sialoprotein, osteopontin (OPN), dentin sialoprotein (DSP), dentin phosphoprotein (DPP), C-terminal fragment of dentin matrix protein 1 (DMP1-C), and proteoglycan versions of DSP (DSP-PG) and DMP1 (DMP1-PG) were tested individually to determine their roles in collagen fibrillogenesis and the prevention of denaturation. It was shown that DSP and DPP slowed down fibrillogenesis, while other SIBLINGs had limited impact. In addition, the denaturation time was faster in the presence of DSP and OPN, indicating a negative impact. The role of calcium ions in these processes was also investigated. The presence of calcium ions sped up fibrillogenesis in all scenarios tested, but it had a negative impact by reducing the extent. Calcium also sped up the denaturation in most cases, with the exception of DMP1-C and DSP where the opposite was seen. Calcium had a similar effect on the proteoglycan variants in the fibrillogenesis process, but had no impact on the denaturation process in the presence of these two. It is believed that incorporating DMP1-C or DSP on the surface of a bone implant may improve the collagen interactions with the implant, thereby facilitating improved osteointegration.
Means (upāya) – Āṇavopāya, Śāktopāya, Śāmbhavopāya – Ācārya dr. Sthaneshwar Timalsina
Creators: name: Timalsina, Staneshwar
Publisher: name: Zenodo
Year: 2021
Subjects: Guhyakālī
Kubjika
amnaya
Kaula
timalsina
Divine Mother
consciousness
krama
Kula
Īśāna
shakta upāya
Saundaryalahari
Mālinīvijayottaratantra
Chandi
advaita vedanta
sthaneshwar timalsina
vimarsha-foundation
Sarvamnaya
Abhinavagupta
vedanta
Kali
Devi Mahatmya
trika
Spanda
Shiva Sutra
Tantra
mahadeva
saivadvaita
shakti
sarvamnaya-oral-tradition-archive
Vasugupta
Tripura Rahasya
sarvamnaya
anava upaya
agama
Sadāśiva
Camunda
Shiva
Bhairava
yantra
Mahakali
tripura
Tantric philosophy
Shaiva
tantraloka
Durga
shambhava
Kashmir Shaivism
Tripurasundari

description: In this video Śaivācārya Sthaneshwar Timalsina discusses Kashmir Shaivism's upāya system, and the importance of these means in recognising our essential nature as Śiva or Supreme Consciousness. Each of the upāyas are connected with an innate faculty or power of consciousness: śāmbhavopāya with ichhā or will; śāktopāya with jñana or knowledge; and āṇavopāya with kriyā or action. Despite their practical differences in relation to the different stages of Consciousness, all of them are equally important in the spiritual path.

Original YouTube video: https://www.youtube.com/watch?v=NolQeC-ONCA

This presentation is part of the Sarvāmnāya Oral Tradition Archive.
Vimarsha Foundation. (2025). The Sarvāmnāya Oral Tradition Archive [Data set]. Zenodo. https://doi.org/10.5281/zenodo.15188107
Consumer acceptance and preference for brown rice—A mixed‐method qualitative study from Nepal
Creators: name: Gyawali, Pratiksha
name: Tamrakar, Dipesh
name: Shrestha, Abha
name: Shrestha, Himal
name: Karmacharya, Sanju
name: Bhattarai, Sanju
name: Bhandari, Niroj
name: Malik, Vasanti
name: Mattei, Josiemer
name: Spiegelman, Donna
name: Shrestha, Archana
Publisher: name: La Trobe
Year: 2022

description: No description supplied
Associations of atopy and asthma during aging of an adult population over a 20-year follow-up
Creators: name: Diogenes S. Ferreira
name: Kaushik, Sonia
name: Smith, Catherine L.
name: Shyamali C. Dharmage
name: Geza P. Benke
name: Thompson, Bruce R.
name: E. Haydn Walters
name: Wolfe, Rory
name: Abramson, Michael J.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objective: Atopy is associated with asthma, but cross-sectional studies suggest this association may be weaker in older adults. It remains unclear if atopy predicts asthma later in adult life. We aimed to investigate whether atopy in young adults predicted asthma 20 years later and to quantify the contemporaneous relationship of atopy and asthma as adults age. Methods: Participants of the European Community Respiratory Health Survey (ECRHS) in Melbourne aged 20–44 years were followed for 20 years and completed questionnaires, skin prick tests (SPT) and allergen specific immunoglobulin E measurement at a baseline and two subsequent surveys. Using logistic regression and generalized estimating equations, we tested if atopy at baseline predicted current asthma later in life and estimated the association between current atopy measured at each survey and current asthma, while adjusting for potential confounders. Results: The analysis included 220 participants: 50.9% male. Mean (SD) age at baseline was 35.7 (5.7) years. Asthma and atopy prevalence remained stable over 20 years. Baseline atopy (SPT) was associated with current asthma (OR 9.74, 95%CI 4.22, 22.5) over 20 years, and current atopy (SPT) with concurrent asthma (3.12; 1.70, 5.74). Conclusions: Atopy remains strongly associated with current asthma in 40 to 64 year-old adults, both prospectively and contemporaneously, but the prospective association is stronger.
Directing Dissent: Governing Political Dissidence in Spanish Prisons
Creators: name: Hogg, Alison
Publisher: name: Universität Tübingen
Year: 2012
Subjects: subject: Politischer Gefangener , Gefängnis , Spanien
subject: 360
subject: Political prisoner
subject: political praxis
subject: normalization
subject: fragmentation
subject: risk management

description: Under article 25.2 of the Spanish Constitution the incarceration of a person should aim to re-educate and socially rehabilitate. Along the same line, Art. 59.2 of the General Penitentiary Law of 21 September 1979 asserts that treatment in prisons, should aim to motivate the incarcerated to become law abiding and to respect themselves, their family, peers, and society. This is allegedly achieved by them serving their sentences under conditions that reflect their individualized scientific grade (Art. 72 GPL). How do these aims translate into practice for a group of individuals, ETA members, condemned for offenses committed in reaction to a perceived oppressive majoritarianism? It is hypothesized that the Spanish state either rehabilitates the deviants thus showing them the error of their ways and directs them to normality through a highly individualized assessment based on politically constructed common factors, or contains and civically and politically excludes those who resist. A Foucauldian approach is used to analyze the mechanisms of power and, the security and penal apparatuses erected to manage and discipline this collective, more precisely of governmentality, normalization, and of biopower. Particular attention is paid to the techniques used to ‘normalize’ and govern this collective. At first sight, one would think that only disciplinary mechanisms in a penitentiary setting need be used to achieve the earlier stated aims given that they have a ‘captive audience’; however, in reaction to an intransigent collective with an embedded political praxis, the State has adopted a hybridized system of power. The system combines individual and collective security mechanisms, and legal instruments to achieve this objective. In managing risk, the Spanish penal apparatus has adopted strategies that involve politically and civically castrating those that are deemed too high a risk and incorrigible.