title: ÐÐ¼Ð¼ÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð°ÑÐºÐµÑÑ Ð² Ð¾ÑÐµÐ½ÐºÐµ ÑÑÐµÐ¿ÐµÐ½Ð¸ Ð½ÐµÐ²ÑÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ñ Ð½Ð°ÑÑÑÐµÐ½Ð¸Ð¹, Ð¸Ð½Ð´ÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ ÑÐ°Ð·Ð²Ð¸ÑÐ¸ÐµÐ¼ Ð¾Ð¿ÑÑ Ð¾Ð»ÐµÐ²Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ° (ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð¾Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Immunological markers in assessing the degree of neurological disorders induced by the development of the tumor process (experimental study)
Creators: name: ÐÑÐ´ÑÐºÐ¾, ÐÐ»ÐµÐºÑÐ°Ð½Ð´Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÐºÐ¾Ð³Ð½Ð¸ÑÐ¸Ð²Ð½ÑÐµ ÑÐµÑÑÑ
Ð¸Ð¼Ð¼ÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð°ÑÐºÐµÑÑ
Ð½ÐµÐ²ÑÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ°Ñ Ð¾ÑÐµÐ½ÐºÐ°
Ð¿Ð¾ÑÐ°Ð¶ÐµÐ½Ð¸Ñ Ð½ÐµÑÐ²Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ
Ñ Ð¸Ð¼Ð¸Ð¾ÑÐµÑÐ°Ð¿Ð¸Ñ
ÑÐ¸ÑÐ¾ÑÑÐ°ÑÐ¸ÐºÐ¸
Ð¦Ð¸ÑÐ¿Ð»Ð°ÑÐ¸Ð½
Ð¦Ð¸ÐºÐ»Ð¾ÑÐ¾ÑÑÐ°Ð¼Ð¸Ð´
Ð»ÐµÐ¹ÐºÐ¾Ð· Ð -388
Ð°Ð´ÐµÐ½Ð¾ÐºÐ°ÑÑÐµÐ½Ð¾Ð¼Ð° ÑÐ¾Ð»ÑÑÐ¾Ð¹ ÐºÐ¸ÑÐºÐ¸ Ð¡Ð¢-26
cognitive tests
immunological markers
neurological evalluation
nervous system disorders
chemotherapy
cytostats
Cysplatin
Cyclophosphamide
R-388 leukemia
ST-26 colon adenocarcenoma

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description: The work is devoted to the study of patterns between immunological markers, the results of cognitive tests and neurological assessment of the state of the nervous system when it is damaged in the mouth, the development of malignant tumors and experimental chemotherapy. The NCBI electronic database was used to collect literature data. The work was performed on the basis of the Center for Preclinical and Clinical Studies of the National Research Center "Kurchatov Institute" - PNPI (Gatchina), where a significant part of the factual material was collected. Experiments were carried out showing how different chemotherapy drugs and tumor types affect the state of the nervous system and how the concentrations of immunological factors and the results of neurological assessment combined with cognitive tests are interconnected. The results were statistically processed using the SPSS for Windows program. applying the methods of mathematical statistics. As a result, the effect of tumors and chemotherapy drugs on the nervous system was proven, the stages of effects were shown when evaluating the results of separate testing, differences in the degree of damage to parts of the nervous system, and the synergy of effects in the treatment of malignant neoplasms with chemotherapy was confirmed.