cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Erbium emitters in commercially fabricated nanophotonic silicon waveguides
Creators: name: Rinner, Stephan
name: Burger, Florian
name: Gritsch, Andreas
name: Schmitt, Jonas
name: Reiserer, Andreas
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Quantum memories integrated into nanophotonic silicon devices are a promising platform for large quantum networks and scalable photonic quantum computers. In this context, erbium dopants are particularly attractive, as they combine optical transitions in the telecommunications frequency band with the potential for second-long coherence time. Here we show that these emitters can be reliably integrated into commercially fabricated low-loss waveguides. We investigate several integration procedures and obtain ensembles of many emitters with an inhomogeneous broadening of < 2 GHz and a homogeneous linewidth of < 30 kHz. We further observe the splitting of the electronic spin states in a magnetic field up to 9 T that freezes paramagnetic impurities. Our findings are an important step towards long-lived quantum memories that can be fabricated on a wafer-scale using CMOS technology.
(101391) Thomas Burdett Warren
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: A pictorial review of breast biopsy complications
Creators: name: Hiraoka Catani, Juliana
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Metastases
subject: Infection
subject: Haemorrhage
subject: Complications
subject: Biopsy
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Mammography
subject: Interventional non-vascular
subject: Breast

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: to describe and illustrate some complications of percutaneous breast biopsies; to describe the management principles for the main complications of percutaneous breast...
Lower rates of cardiovascular events and mortality associated with liraglutide use in patients treated with basal insulin: A DEVOTE subanalysis (DEVOTE 10)
Creators: name: Brown-Frandsen, K.
name: Emerson, S.S.
name: Pratley, R.E.
name: Zinman, B.
name: Lange, M.
name: Pieber, T.R.
name: McGuire, D.K.
name: Poulter, N.R.
name: Moses, A.C.
name: Ranthe, M.F.
name: Grøn, R.
name: Örsy, P.
name: DEVOTE Study Group
name: Buse, J.B.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aim: To compare the associations between concomitant liraglutide use versus no liraglutide use and the risk of major adverse cardiovascular events (MACE) and all-cause mortality among patients receiving basal insulin (either insulin degludec [degludec] or insulin glargine 100 units/mL [glargine U100]) in the Trial Comparing Cardiovascular Safety of Insulin Degludec versus Insulin Glargine in Patients with Type 2 Diabetes at High Risk of Cardiovascular Events (DEVOTE). Materials and Methods: Patients with type 2 diabetes and high cardiovascular risk were randomized 1:1 to degludec or glargine U100. Hazard ratios for MACE/mortality were calculated using a Cox regression model adjusted for treatment and time-varying liraglutide use at any time during the trial, without interaction. Sensitivity analyses were adjusted for baseline covariates including, but not limited to, age, sex, smoking and prior cardiovascular disease. Results: At baseline, 436/7637 (5.7%) patients were treated with liraglutide; after baseline, 187/7637 (2.4%) started and 210/7637 (2.7%) stopped liraglutide. Mean liraglutide exposure from randomization was 530.2 days. Liraglutide use versus no liraglutide use was associated with significantly lower hazard rates for MACE [0.62 (0.41; 0.92)95%CI] and all-cause mortality [0.50 (0.29; 0.88)95%CI]. There was no significant difference in the rate of severe hypoglycaemia with versus without liraglutide use. Multiple sensitivity analyses yielded similar results. Conclusions: Use of liraglutide was associated with significantly lower risk of MACE and death in patients with type 2 diabetes and high cardiovascular risk using basal insulin.
Sodium-glucose co-transporter-2 inhibitor use and risk of lower-extremity amputation: Evolving questions, evolving answers
Creators: name: Wang, T.
name: Pate, V.
name: Crowley, M.J.
name: Buse, J.B.
name: Stürmer, T.
name: Gower, E.W.
name: Yang, J.Y.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aim: To examine whether sodium-glucose co-transporter-2 (SGLT2) inhibitors are associated with a higher risk of lower-extremity amputation than dipeptidyl-peptidase-4 (DPP-4) inhibitors and sulphonylureas. Methods: We conducted a retrospective cohort study, using the MarketScan Commercial Claims and Encounters Database (2013-2015), to compare the incidence of lower-extremity amputation (LEA) between initiators of SGLT2 inhibitors and initiators of two second-line drugs, DPP-4 inhibitors and sulphonylureas (SUs). We estimated crude incidence rates (IRs) and adjusted hazard ratios (aHR), with 95% confidence intervals (CIs), before and after propensity-score weighting. We additionally conducted sensitivity analyses using a comparator group of all non-metformin, non-SGLT2 inhibitor glucose-lowering drugs, as previous studies used this approach. Results: In a cohort of 328 150 individuals aged 18 to 64 years, the IR of LEA ranged from 1.5 to 2.4 per 1000 person-years. In as-treated analysis, the estimated hazard of LEA was increased among SGLT2 inhibitor initiators compared to DPP-4 inhibitor initiators (aHR 1.69, 95% CI 1.20-2.38), but not compared to SU initiators (aHR 1.02, 95% CI 0.67-1.55) or non-metformin, non-SGLT2 inhibitor initiators (aHR 1.02, 95% CI 0.54-1.93). Results were consistent in intention-to-treat analysis and across a number of sensitivity analyses. Conclusions: Among commercially insured patients in the United States, our results suggest that initiation of SGLT2 inhibitors may increase the risk of LEA compared to initiation of DPP-4 inhibitors. Contrasting results when comparing SGLT2 inhibitor initiators to DPP-4 inhibitor and SU initiators highlight the importance of choosing appropriate comparator drugs when addressing comparative effectiveness and safety questions that can inform clinical decision-making.
title: Chest CT: Can lower dose levels produce clinical appropriate image quality?
Creators: name: Cojocaru, Adriana
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Image verification
subject: Radiation safety
subject: CT
subject: Radioprotection / Radiation dose

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Chest Computed Tomography (CT) is considered the gold standard for the assessment of most pulmonary diseases. Publications have demonstrated that the continuing expansion of CT practice has increased the radiation burden to the general...
New binaries among UV-selected, hot subdwarf stars and population properties
Creators: name: Kawka, A.
name: Vennes, S.
name: O'Toole, S.
name: Nemeth, P.
name: Burton, D.
name: Kotze, E.
name: Buckley, D. A. H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We have measured the orbital parameters of seven close binaries, including six new objects, in a radial velocity survey of 38 objects comprising a hot subdwarf star with orbital periods ranging from ~0.17 to 3 d. One new system, GALEX J2205-3141, shows reflection on a M dwarf companion. Three other objects show significant short-period variations, but their orbital parameters could not be constrained. Two systems comprising a hot subdwarf paired with a bright main-sequence/giant companion display short-period photometric variations possibly due to irradiation or stellar activity and are also short-period candidates. All except two candidates were drawn from a selection of subluminous stars in the Galaxy Evolution Explorer ultraviolet sky survey. Our new identifications also include a low-mass subdwarf B star and likely progenitor of a low mass white dwarf (GALEX J0805-1058) paired with an unseen, possibly substellar, companion. The mass functions of the newly identified binaries imply minimum secondary masses ranging from 0.03 to 0.39 M_solar. Photometric time series suggest that, apart from GALEX J0805-1058 and J2205-3141, the companions are most likely white dwarfs. We update the binary population statistics: Close to 40 per cent of hot subdwarfs have a companion. Also, we found that the secondary mass distribution shows a low-mass peak attributed to late-type dwarfs, and a higher-mass peak and tail distribution attributed to white dwarfs and a few spectroscopic composites. Also, we found that the population kinematics imply an old age and include a few likely halo population members.
description: Accepted for publication in MNRAS
(101392) Michael Mahony
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Impact of metformin use on the cardiovascular effects of dipeptidyl peptidase-4 inhibitors: An analysis of Medicare claims data from 2007 to 2015
Creators: name: Stürmer, T.
name: Buse, J.B.
name: Gokhale, M.
name: Crowley, M.J.
name: Pate, V.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aims: To examine the outcomes of dipeptidyl peptidase-4 (DPP-4) inhibitor initiation with and without concurrent metformin treatment. Materials and methods: We identified Medicare enrollees initiating a DPP-4 inhibitor, a sulphonylurea or a thiazolidinedione. Using propensity-score-weighted Poisson models, we evaluated 1-year cardiovascular (CV) outcome incidence among initiators of DPP-4 inhibitors versus comparators in subgroups with and without concurrent metformin use, and assessed the interaction between initiation drug and metformin. Outcomes included mortality, non-fatal myocardial infarction (MI), stroke, and a composite outcome. Results: For the DPP-4 inhibitor (n = 13 391) versus sulphonylurea (n = 33 206) comparison, rate differences in composite outcome incidence favoured DPP-4 inhibitors: −2.0/100 person-years among metformin users (95% confidence interval [CI] −2.7 to −1.3) and − 1.0/100 person-years (95% CI −1.8 to −0.2) among metformin non-users. Similar rate difference trends among metformin users and non-users were seen for mortality (−1.5/100 person-years [95% CI −2.1 to −0.9] and −0.7/100 person-years [95% CI −1.4 to 0.0]) and non-fatal MI (−0.5/100 person-years [95% CI −0.8, −0.3] and 0.1/100 person-years [95% CI −0.2 to 0.4]). The interaction between DPP-4 inhibitor initiation and metformin was statistically significant for non-fatal MI (P = 0.008). For the DPP-4 inhibitor (n = 22 210) versus thiazolidinedione (n = 9517) comparison, rate differences in composite outcome incidence for DPP-4 inhibitor initiation were −0.6/100 person-years (95% CI −1.5 to 0.2) among metformin users and 1.0 (95% CI 0.0 to 2.0) among metformin non-users. Similar rate difference trends among metformin users and non-users were seen for mortality (−0.5/100 person-years [95% CI −1.3 to 0.1] and 0.8/100 person-years [95% CI −0.0 to 1.7]) and non-fatal MI (−0.1/100 person-years [95% CI −0.4 to 0.2] and 0.2/100 person-years [95% CI −0.1 to 0.6]). The interaction between DPP-4 inhibitor initiation and metformin was statistically significant for the composite outcome (P = 0.024) and mortality (P = 0.023). Conclusion: Incidence rate differences in multiple CV outcomes appeared more favourable when DPP-4 inhibitor initiation occurred in the presence of metformin, suggesting a possible interaction between DPP-4 inhibitors and metformin.
Health-related quality of life in people with type 2 diabetes participating in the LEADER trial
Creators: name: Pocock, S.
name: Nauck, M.A.
name: LEADER Publication Committee for the LEADER Trial Investigators
name: Frimer-Larsen, H.
name: Gray, A.
name: Mann, J.F.E.
name: Bosch-Traberg, H.
name: Buse, J.B.
name: Ye, Q.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aims: To assess health-related quality of life (HRQoL) in people with type 2 diabetes (T2D) participating in the LEADER cardiovascular outcomes trial using the five-dimension European Quality of Life questionnaire (EQ-5D). Materials and methods: The EQ-5D was administered every 12 months in a subset of patients from Canada, Denmark, Germany, Ireland, Italy, Netherlands, Spain, Sweden, the United Kingdom and the United States. We compared changes in utility index scores and visual analogue scale (VAS) scores from baseline to 36 months in participants treated with liraglutide and placebo. We also assessed which complications had the greatest impact on quality of life. Results: At 36 months, less deterioration in EQ-5D utility index score was seen in the liraglutide group (−0.058) than in the placebo group (−0.082; estimated treatment difference [ETD] 0.023, 95% confidence interval [CI] 0.004;0.043; P = 0.020). A smaller decrease in EQ-5D VAS score was also demonstrated in the liraglutide group (−3.51) vs. the placebo group (−5.45; ETD 1.94, 95% CI 0.32;3.57; P = 0.019). The benefits of liraglutide treatment compared with placebo were driven primarily by shifts in the domains of mobility and self-care. The most influential events contributing to poorer HRQoL were stroke, heart failure, malignant neoplasm and confirmed hypoglycaemia. Conclusions: Liraglutide demonstrated a modest but significant benefit in patient-reported health status using the EQ-5D, compared with placebo. This benefit may be of clinical relevance and requires further study.
title: A pictorial review of a rare breast malignant subtype: invasive micropapillary breast carcinoma.
Creators: name: Hiraoka Catani, Juliana
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Breast
subject: Oncology
subject: Mammography
subject: Ultrasound
subject: MR
subject: Biopsy
subject: Neoplasia
subject: Pathology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: to describe the main imaging findings of invasive micropapillary breast carcinomas (IMPC); to highlight the aspects that can raise the possibility of a IMPC, instead of a invasive ductal carcinoma (IDC) and why IMPC is clinically important; to...
Anomalous $WWγ$ couplings with beam polarization at the Compact Linear Collider
Creators: name: Arı, V.
name: Billur, A. A.
name: İnan, S. C.
name: Köksal, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the anomalous $WWγ$ couplings at the Compact Linear Collider through the processes $e^{+}e^{-}\to W^+W^-$, $e^{-}e^{+} \to e^{-} γ^{*} e^{+} \to e^{+} ν_{e} W^-$ and $e^{-}e^{+}\to e^{-} γ^{*} γ^{*} e^{+} \to e^{-} W^+ W^- e^{+} $ $ (γ^{*}$ is the Weizsacker-Williams photon). We give the 95\% confidence level limits for unpolarized and polarized electron (positron) beam on the anomalous couplings for various values of the integrated luminosities and center-of-mass energies. We show that the obtained limits on the anomalous couplings through these processes can highly improve the current experimental limits. In addition, our limits with beam polarization are approximately two times better than the unpolarized case.
description: Tables and references added
Study design choices for evaluating the comparative safety of diabetes medications: An evaluation of pioglitazone use and risk of bladder cancer in older US adults with type-2 diabetes
Creators: name: Gokhale, M.
name: Buse, J.B.
name: Garry, E.M.
name: Pate, V.
name: Stürmer, T.
name: Nielsen, M.E.
name: Lund, J.L.
Publisher: name: Blackwell Publishing Ltd
Year: 2019

description: Aim: The aim of the study was to empirically demonstrate the effect of varying study designs when evaluating the safety of pioglitazone in treating bladder cancer. Methods: We identified Medicare beneficiaries above 65 years of age with diabetes between 2008 and 2015 and with classified exposure (at least two claims within 180 days) to glucose-lowering drugs (GLD), pioglitazone or another drug. The effects of varying the following study design parameters on bladder cancer risk were assessed: use of a new vs existing drug, choice of referent (all non-users and users of GLDs, non-insulin GLDs and DPP-4s) and whether or not censoring accounted for treatment change. We used the Cox proportional hazards model to obtain adjusted HRs and 95% CIs. Results: We included 1,510,212 patients classified as pioglitazone users (N = 135,188) or non-users (N = 1,375,024). Users had more diabetic complications than non-users, but fewer than insulin users. The HR ranged from 1.10 (1.01-1.20) to 1.13 (0.99-1.29) when censoring ignored treatment change, suggesting a weak association or none between pioglitazone and bladder cancer, probably under-estimating risk. However, the HR was 1.20 (1.01-1.42) when cohorts were restricted to new users, censored upon treatment change, and when DPP-4 was used as the referent, suggesting an increased risk of bladder cancer associated with pioglitazone. Conclusions: The continued demand for new GLDs indicates the need for more robust observational methods to improve the value of generating real-world evidence in equipping clinicians to make informed prescribing decisions. Although there is no one-size-fits-all approach, we recommend active comparator new user study designs that compare therapeutically equivalent drugs and account for treatment changes during follow-up to present the least biased comparative safety estimates.
(101394) Caine Mahony
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Non-syndromic craniosynostosis – the journey from diagnosis to surgery and beyond
Creators: name: Nejadhamzeeigilani, Hamed
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Education and training
subject: Surgery
subject: Education
subject: CT
subject: Conventional radiography
subject: Paediatric
subject: Neuroradiology brain
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: We aim to provide an educational pictorial review in order to: Demonstrate radiological features of non-syndromic craniosynostosis. Highlight the role of imaging in the pre- and post-operative management. Provide an insight into the different...
(101388) Harriet Josephine Mahon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Erprobung eines Gruppentests zur Überprüfung des Grammatikverständnisses auf der Basis des TROG-D
title: Testing a group test for reception of Grammar based on the TROG-D
titleType: AlternativeTitle
Creators: name: Lüke, Timo
name: Ritterfeld, Ute
name: Tröster, Heinrich
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: Grammatik
subject: Gruppentestung
subject: Screening
subject: Sprachentwicklung
subject: TROG-D
subject: 370
subject: Grammatik |
subject: Gruppentest |
subject: Screening |
subject: Sprachentwicklung |
subject: TROG-D |

description: Zur Erfassung der rezeptiven grammatischen Kompetenzen liegt mit dem TROG-D (basierend auf dem englischsprachigen Test for Reception of Grammar; Bishop, 1989) ein anerkanntes Verfahren vor, das im Einzelsetting durchgeführt werden muss und so einschließlich Auswertung etwa eine halbe Stunde pro TeilnehmerIn beansprucht. In der vorliegenden Studie wurde ein auf dem TROG-D basierender Gruppentest erprobt, der den Einsatz beispielsweise in Schulklassen ermöglichen soll. Die überarbeitete Testversion wurde an 93 Zweit- und DrittklässlerInnen erprobt. Zwei Wochen später wurden alle TeilnehmerInnen mit dem TROG-D im Einzelsetting getestet. Eine ROC-Analyse (Receiver Operating Characteristic) und etablierte Screening-Gütekriterien lieferten klare Belege dafür, dass es mit dem Gruppentest gelingt, diejenigen Kinder zu identifizieren, die sich auch in der Einzeltestung mit dem TROG-D als unterdurchschnittlich erweisen. Die Ergebnisse belegen das grundsätzlich große Potential eines solchen Gruppentests und geben Ansatzpunkte zur Weiterentwicklung dieser Vorgehensweise.
Long-term Cost-effectiveness of Insulin Degludec Versus Insulin Glargine U100 in the UK: Evidence from the Basal-bolus Subgroup of the DEVOTE Trial (DEVOTE 16)
Creators: name: Magnuson, E.A.
name: Pollock, R.F.
name: Marso, S.P.
name: Andersen, A.
name: Hallén, N.
name: Tutkunkardas, D.
name: Buse, J.B.
name: Valentine, W.J.
name: Gundgaard, J.
name: DEVOTE study group
Publisher: name: Springer International Publishing
Year: 2019

description: Objectives: To evaluate the cost-effectiveness of insulin degludec (degludec) versus insulin glargine 100 units/mL (glargine U100) in basal–bolus regimens for patients with type 2 diabetes (T2D) at high cardiovascular (CV) risk based on the DEVOTE CV outcomes trial. Methods: A microsimulation model, informed by clinical outcomes from the subgroup of patients using basal–bolus insulin therapy in DEVOTE (NCT01959529) and by the UKPDS Outcomes Model 2 risk equations, was used to model direct costs (2018 GBP) and effectiveness outcomes [quality-adjusted life years (QALYs)] with degludec versus glargine U100 over a 40-year time horizon. The model captured the development of eight diabetes-related complications, death, severe hypoglycemia and insulin dosing. This analysis was conducted from the perspective of National Health Service (NHS) England. Results: Treatment with degludec versus glargine U100 in basal–bolus regimens was associated with improved clinical outcomes at a higher cost per patient [incremental cost effectiveness ratio (ICER): £14,956 GBP/QALY]. Degludec remained cost effective versus glargine U100 in all exploratory sensitivity analyses, with ICERs below the widely accepted willingness-to-pay threshold, although the result was most sensitive to assumptions regarding the persistence of treatment effects. Conclusions: Our long-term modeling analysis suggested that degludec was cost effective (from the perspective of NHS England) versus glargine U100 in basal–bolus regimens for patients with T2D at high CV risk. Our findings raise important questions regarding how to model the health economics of diabetes therapies.
title: Cardiac CT in Electrophysiology Intervention
Creators: name: Liddy, Stephen
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Ablation procedures
subject: CT
subject: Hybrid Imaging
subject: Cardiovascular system
subject: Cardiac
subject: Haemodynamics / Flow dynamics

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: This posterwill review the applicationsof cardiac CT in electrophysiology intervention with a particular focus on pulmonary vein isolation, left atrial appendage occlusion and cardiac device...
Performance of a computable phenotype for identification of patients with diabetes within PCORnet: The Patient-Centered Clinical Research Network
Creators: name: Katalenich, B.L.
name: Chakkalakal, R.J.
name: Buse, J.B.
name: Ayala, S.G.
name: Donahoo, W.T.
name: Epstein, B.F.
name: Wiese, A.D.
name: Worley, K.J.
name: Morris, H.L.
name: Cook, M.M.
name: Fanous, N.
name: Grijalva, C.G.
name: Roumie, C.L.
name: Knoepp, P.
name: Rothman, R.L.
name: Bradford, R.
name: Zalimeni, E.
name: Guzman, H.
name: Bachmann, K.N.
Publisher: name: John Wiley and Sons Ltd
Year: 2019

description: Purpose: PCORnet, the National Patient-Centered Clinical Research Network, represents an innovative system for the conduct of observational and pragmatic studies. We describe the identification and validation of a retrospective cohort of patients with type 2 diabetes (T2DM) from four PCORnet sites. Methods: We adapted existing computable phenotypes (CP) for the identification of patients with T2DM and evaluated their performance across four PCORnet sites (2012-2016). Patients entered the cohort on the earliest date they met one of three CP categories: (CP1) coded T2DM diagnosis (ICD-9/ICD-10) and an antidiabetic prescription, (CP2) diagnosis and glycosylated hemoglobin (HbA1c) ≥6.5%, or (CP3) an antidiabetic prescription and HbA1c ≥6.5%. We required evidence of health care utilization in each of the 2 prior years for each patient, as we also developed an incident T2DM CP to identify the subset of patients without documentation of T2DM in the 365 days before t 0 . Among a systematic sample of patients, we calculated the positive predictive value (PPV) for the T2DM CP and incident-T2DM CP using electronic health record (EHR) review as reference. Results: The CP identified 50 657 patients with T2DM. The PPV of patients randomly selected for validation was 96.2% (n = 1572; CI:95.1-97.0) and was consistently high across sites. The PPV for the incident-T2DM CP was 5.8% (CI:4.5-7.5). Conclusions: The T2DM CP accurately and efficiently identified patients with T2DM across multiple sites that participate in PCORnet, although the incident T2DM CP requires further study. PCORnet is a valuable data source for future epidemiological and comparative effectiveness research among patients with T2DM.
Long-Term Dynamics of Planetesimals in Planetary Chaotic Zones
Creators: name: Demidova, Tatiana
name: Shevchenko, Ivan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences
subject: J.2.3
subject: 70F15

description: Extensive numerical experiments on the long-term dynamics of planetesimals near the orbits of planets around single stars with debris disks have been carried out. The radial sizes of planetesimal clusters and the planetary chaotic zone as a function of mass parameter $μ$ (planet-star mass ratio) have been determined numerically with a high accuracy separately for the outer and inner parts of the chaotic zone. The results obtained have been analyzed and interpreted in light of existing analytical theories (based on the planet-planetesimal mean motion resonance overlap criterion) and in comparison with previous numerical experiment approaches to the problem. We show and explain how the stepwise dependence of the chaotic zone sizes on $μ$ is determined by the marginal resonances.
description: 11 pages, 6 figures
title: Microcalcifications and comedocarcinoma: from elementary mammographic lesion to final diagnosis
Creators: name: Aouini, Rim
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Breast
subject: Oncology
subject: Mammography
subject: Education
subject: Biopsy
subject: Calcifications / Calculi
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review and describe the morphologic and radiologic features of comedocarcinoma at mammography: Evaluation of morphology, distribution and arrangements of...
Editorial
Creators: name: Neves, Pedro Soares
Publisher: name: CAP - Cadernos de Arte Pública / Public Art Journal
Year: 2022

description: Estes artigos procuram debater e explorar os modos como a Escultura se constitui ontologicamente no presente, as diferentes heranças históricas e a construção do imaginário escultórico. Convidámos a comunidade científica e artística para uma análise crítica e transdisciplinar sobre as repercussões que as múltiplas constituições do que é a Escultura têm não só nas artes, mas também fora do âmbito artístico.
description: CAP - Cadernos de Arte Pública / Public Art Journal, Vol 4 No 2 (2022): Artistic Studies and Sculpture
(101389) John Aldridge Mahon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Entanglement cost and entangling power of bipartite unitary and permutation operators
Creators: name: Chen, Lin
name: Yu, Li
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is known that any bipartite unitary operator of Schmidt rank three is equivalent to a controlled unitary under local unitaries. We propose a standard form of such operators. Using the form we improve the upper bound for the entanglement cost to implement such operators under local operations and classical communications (LOCC), and provide a corresponding protocol. A part of our protocol is based on a recursive-control protocol which is helpful for implementing other unitary operators. We show that any bipartite permutation unitary of Schmidt rank three can be implemented using LOCC and two ebits. We give two protocols for implementing bipartite permutation unitaries of any Schmidt rank $r$, and showed that one of the protocol uses $O(r)$ ebits of entanglement and $O(r)$ bits of classical communication, while these two types of costs for the other protocol scale as $O(r\log r)$ but the actual values are smaller for all $r<1100$. Based on this we obtain upper bounds of the number of nonlocal CNOT gates needed to implement bipartite classical reversible maps using classical circuits under two different conditions. We also quantify the entangling power of bipartite permutation unitaries of Schmidt rank two and three. We show that they are respectively $1$ ebit and some value between $\log_2 9 - 16/9$ and $\log_2 3$ ebits.
description: 27 pages, 2 figures. Minor improvements and corrections compared to v3. Almost the same as the published version except the numbering of theorems and lemmas, etc
Efficacy, safety, and tolerability of oral semaglutide versus placebo added to insulin with or without metformin in patients with type 2 diabetes: The PioNEER 8 trial
Creators: name: Hoff, S.T.
name: Harris, S.B.
name: Buse, J.B.
name: Zinman, B.
name: Cariou, B.
name: Tarp-Johansen, M.J.
name: Pedersen, K.B.
name: Araki, E.
name: Aroda, V.R.
Publisher: name: American Diabetes Association Inc.
Year: 2019

description: OBJECTIVE To investigate the efficacy, safety, and tolerability of oral semaglutide added to insulin with or without metformin. RESEARCH DESIGN AND METHODS Patients with type 2 diabetes uncontrolled on insulin with or without metformin were randomized to oral semaglutide 3 mg (N 5 184), 7 mg (N 5 182), or 14 mg (N 5 181) or to placebo (N 5 184) in a 52-week, double-blind trial. End points were change from baseline to week 26 in HbA1c (primary) and body weight (confirmatory secondary). Two estimands were defined: treatment policy (effect regardless of trial product discontinuation or rescue medication) and trial product (effect assuming trial product continuation without rescue medication) in randomized patients. RESULTS Oral semaglutide was superior to placebo in reducing HbA1c (estimated treatment difference [ETD] –0.5% [95% CI –0.7, –0.3], –0.9% [–1.1, –0.7], and –1.2% [–1.4, –1.0] for 3, 7, and 14 mg, respectively; P < 0.001) and body weight (ETD 20.9 kg [95% CI 21.8, 20.0], 22.0 kg [23.0, 21.0], and 23.3 kg [24.2, 22.3]; P 5 0.0392 for 3 mg, P £ 0.0001 for 7 and 14 mg) at week 26 (treatment policy estimand). Significantly greater dose-dependent HbA1c and body weight reductions versus placebo were achieved with oral semaglutide at weeks 26 and 52 (both estimands). The most frequent adverse event with oral semaglutide was nausea (11.4–23.2% of patients vs. 7.1% with placebo; mostly mild to moderate). CONCLUSIONS Oral semaglutide was superior to placebo in reducing HbA1c and body weight when added to insulin with or without metformin in patients with type 2 diabetes. The safety profile was consistent with other glucagon-like peptide 1 receptor agonists.
The Standard Model cross-over on the lattice
Creators: name: D'Onofrio, Michela
name: Rummukainen, Kari
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: With the physical Higgs mass the Standard Model symmetry restoration phase transition is a smooth cross-over. We study the thermodynamics of the cross-over using numerical lattice Monte Carlo simulations of an effective SU(2) X U(1) gauge + Higgs theory, significantly improving on previously published results. We measure the Higgs field expectation value, thermodynamic quantities like pressure, energy density, speed of sound and heat capacity, and screening masses associated with the Higgs and Z fields. While the cross-over is smooth, it is very well defined with a width of only approximately 5 GeV. We measure the cross-over temperature from the maximum of the susceptibility of the Higgs condensate, with the result $T_c = 159.5 \pm 1.5$ GeV. Outside of the narrow cross-over region the perturbative results agree well with non-perturbative ones.
description: 10 pages
Mobile Application Development for Pet Feeder with using Microcontroller and Internet of things
Creators: name: Jirawat Thaenthong
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2019
Subjects: Pet Feeder
Microcontroller
Sensors
Mobile Application
Internet of Things

description: Journal of Information Science and Technology, 9, 1, 28-40
Comparison of Data Classification Efficiency to Analyze Risk Factors that Affect the Occurrence of Hyperthyroid using Data Mining Techniques
Creators: name: Nattavadee  Hongboonmee
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2019
Subjects: Hyperthyroid
Data Mining
Artificial Neural networks
Naive Bayes
Decision Tree

description: Journal of Information Science and Technology, 9, 1, 41-51
(101390) James Edward Wissett
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
title: Functional MRI in the development of adaptive radiotherapy: imaging evaluation of treatment response in patients with cervical cancer undergone to brachytherapy and external beam radiotherapy
Creators: name: Telesca, Anna Maria
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Image guided radiotherapy
subject: Radiation therapy / Oncology
subject: Imaging sequences
subject: MR-Functional imaging
subject: MR-Diffusion/Perfusion
subject: MR
subject: Pelvis
subject: Oncology

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - Discuss the current role of MRI in radiation therapy treatment planning in patients with cervical cancer - Illustrate the clinical applications of MRI in adaptive radiotherapy approaches to improve dose conformability, reducing normal tissue...
The Study of Perception and Satisfaction of Senior Primary School per 3D Animation Cartoon "Be Patient"
Creators: name: Nattapon  Chatmongkonying
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2019
Subjects: 3D
Animation
Cartoon
Patient
School

description: Journal of Information Science and Technology, 9, 1, 52-62
Dipeptidyl peptidase 4 inhibitors and risk of inflammatory bowel disease: Real-world evidence in U.S. Adults
Creators: name: Sturmer, T.
name: Yang, J.Y.
name: Pate, V.
name: Barnes, E.L.
name: Buse, J.B.
name: Tang, H.
name: Sandler, R.S.
name: Wang, T.
Publisher: name: American Diabetes Association Inc.
Year: 2019

description: OBJECTIVE A recent study raises concerns that dipeptidyl peptidase 4 inhibitors (DPP4i) are associated with increased risk of inflammatory bowel disease (IBD). We evaluated the association between new use of DPP4i and IBD risk compared with other secondline antihyperglycemics. RESEARCH DESIGN AND METHODS We implemented an active-comparator, new-user cohort design using two U.S. administrative claims databases for commercially insured (MarketScan) and older adult (Medicare fee-for-service, 20% random sample) patients from January 2007 to December 2016.We identified patients, aged ≥18 years, who initiated DPP4i versus sulfonylureas (SUs) or initiated DPP4i versus thiazolidinediones (TZDs) and were without prior diagnosis, treatment, or procedure for IBD. The primary outcome was incident IBD, defined by IBD diagnosis preceded by colonoscopy and biopsy and followed by IBD treatment. We performed propensity score weighting to control for measured baseline confounding, estimated adjusted hazard ratios (aHRs [95% CI]) using weighted Cox proportional hazards models, and used randomeffects meta-analysis models to pool aHRs across cohorts. RESULTS We identified 895,747 eligible patients initiating DPP4i, SU, or TZD; IBD incidence rates ranged from 11.6 to 32.3/100,000 person-years. Over a median treatment duration of 1.09-1.69 years, DPP4i were not associated with increased IBD risk across comparisons. The pooled aHRs for IBD were 0.82 (95% CI 0.41-1.61) when comparing DPP4i (n 5 161,612) to SU (n 5 310,550) and 0.76 (0.46-1.26) when comparing DPP4i (n 5 205,570) to TZD (n 5 87,543). CONCLUSIONS Our population-based cohort study of U.S. adults with diabetes suggests that shortterm DPP4i treatment does not increase IBD risk.
Development of websites in the 360 environment temple tourism in the old city of Nakhon Ratchasima.
Creators: name: Inchaya Kumpala
Publisher: name: Faculty of Information Science and Technology, Mahanakorn University of Technology
Year: 2019
Subjects: subject: Websites
subject: 360 Environment
subject: Temple
subject: Tourism
subject: FOS: Economics and business
subject: Old City
subject: Nakhon Ratchasima

description: Journal of Information Science and Technology, 9, 1, 71-80
title: The lifesaving phone call: Acute aortic syndromes
Creators: name: Roriz, Diogo
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Fistula
subject: Dissection
subject: Aneurysms
subject: Diagnostic procedure
subject: CT-Angiography
subject: CT
subject: Thorax
subject: Arteries / Aorta
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: - Describe the different aortic syndromes, their pathophysiology and imaging presentation; - Optimizing theCTtechniquefor the diagnosis and evaluation of the acute aortic syndromes; - Present their prognosis, treatment modalities and main...
Extended Bose-Hubbard Models with Ultracold Magnetic Atoms
Creators: name: Baier, S.
name: Mark, M. J.
name: Petter, D.
name: Aikawa, K.
name: Chomaz, L.
name: Cai, Zi
name: Baranov, M.
name: Zoller, P.
name: Ferlaino, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The Hubbard model underlies our understanding of strongly correlated materials. While its standard form only comprises interaction between particles at the same lattice site, its extension to encompass long-range interaction, which activates terms acting between different sites, is predicted to profoundly alter the quantum behavior of the system. We realize the extended Bose-Hubbard model for an ultracold gas of strongly magnetic erbium atoms in a three-dimensional optical lattice. Controlling the orientation of the atomic dipoles, we reveal the anisotropic character of the onsite interaction and hopping dynamics, and their influence on the superfluid-to-Mott insulator quantum phase transition. Moreover, we observe nearest-neighbor interaction, which is a genuine consequence of the long-range nature of dipolar interactions. Our results lay the groundwork for future studies of novel exotic many-body quantum phases.
description: 11 pages, 7 figures
Dibaryons at COSY
Creators: name: Bashkanov, M.
name: Clement, H.
name: Watts, D. P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Experiments at the Juelich Cooler Synchrotron (COSY) have now found compelling evidence for a new resonant state in the two-baryon system with mass 2380 MeV and a width of 70 MeV. The structure, containing six valence quarks, constitutes a so-called dibaryon, either a hexaquark or a hadronic molecule. The present knowledge about the dibaryon as well as other implications and possible future experiments are discussed.
description: NSTAR2015 conference proceedings
title: Complications after femoral artery catheterization: Hallmarks for the imaging diagnosis
Creators: name: Antunes, Natalie
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Haemorrhage
subject: Fistula
subject: Aneurysms
subject: Complications
subject: Ultrasound
subject: CT-Angiography
subject: CT
subject: Vascular
subject: Interventional vascular
subject: Arteries / Aorta

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of our educational exhibit is to recognize the different complications that can arise after femoral artery catheterization using non-invasive modalities - ultrasound (US) and computer tomographic angiography (Angio-CT) - focusing mainly...
title: Imaging of Pleural Effusion: Comparing Ultrasound, X-Ray and CT findings
Creators: name: Antunes, Natalie
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Thorax
subject: Lung
subject: CT
subject: Conventional radiography
subject: Ultrasound
subject: Diagnostic procedure
subject: Education and training

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The purpose of our educational exhibit is to review the role of noninvasive imaging modalities for the diagnosis and assessment of pleural effusion. We will compare x-ray, ultrasound (US) and CT findings, illustrating the pros and cons of each...