cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Dirac-Moshinsky Oscillator: Theory and Applications
Creators: name: Sadurni, Emerson
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: This work summarizes the most important developments in the construction and application of the Dirac-Moshinsky oscillator (DMO) with which the author has come in contact. The literature on the subject is voluminous, mostly because of the avenues that exact solvability opens towards our understanding of relativistic quantum mechanics. Here we make an effort to present the subject in chronological order and also in increasing degree of complexity of its parts. We start our discussion with the seminal paper by Moshinsky and Szczepaniak and the immediate implications stemming from it. Then we analyze the extensions of this model to many particles. The one-particle DMO is revisited in the light of the Jaynes-Cummings model in quantum optics and exactly solvable extensions are presented. Applications and implementations in hexagonal lattices are given, with a particular emphasis in the emulation of graphene in electromagnetic billiards.
description: Lecture notes from the course "The Dirac-Moshinsky Oscillator: Theory and Applications". To appear in the proceedings of ELAF 2010, Mexico. 28 figures, 45 pages
Proteomic Profiling of Purkinje Cell Surface Reveals the Critical Role of Armadillo-like helical domain containing protein 4 in Mammalian Dendrite Morphogenesis
Creators: name: Sinantha-Hu, Miley
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Biology
subject: Molecular biology
subject: Genetics
subject: FOS: Biological sciences
subject: Proteomics
subject: Morphogenesis
subject: Developmental biology
subject: Neurodevelopment
subject: Dendrites

description: Improper dendrite development is exhibited in a range of human neurodevelopmental disorders and neurodegenerative diseases, such as autism spectrum disorder and schizophrenia. Yet, the underlying molecular mechanisms of dendrite morphogenesis are not well characterized. During neuronal development, highly conserved, precisely timed protein interactions at the cell surface mediate dendrite morphogenesis; therefore, cell surface protein identification and characterization may provide key insights to the intricate molecular processes essential to proper dendrite development. Using cell surface proteomic datasets attained by a novel spatiotemporally resolved proteomic profiling technique in situ, we instructed a loss-of-function candidate screen of 13 cell surface proteins to observe their impacts on dendrite morphology. We found that in vivo disruption of the transmembrane protein Armadillo-like helical domain-containing protein 4 (Armh4) engendered a striking dendrite morphological phenotype in transfected cerebellar Purkinje cells. Armh4 disrupted cells exhibited significant height deficiency, decreased total dendrite length and branching, and growth of additional primary dendrites. Here, we present the critical cell-autonomous function and characterization of the signaling mechanisms of the Purkinje cell surface protein Armadillo-like helical domain containing protein 4 (Armh4) during dendrite morphogenesis. We demonstrate that dendrite morphogenesis is sensitive to Armh4 cell surface levels and that endocytosis is required for Armh4 signaling downregulation in proper dendrite development.
Phenomenological analysis of the double pion production in nucleon-nucleon collisions up to 2.2 GeV
Creators: name: Cao, Xu
name: Zou, Bing-Song
name: Xu, Hu-Shan
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: With an effective Lagrangian approach, we analyze several NN \to NNππchannels by including various resonances with mass up to 1.72 GeV. For the channels with the pion pair of isospin zero, we confirm the dominance of N*(1440)\to Nσin the near threshold region. At higher energies and for channels with the final pion pair of isospin one, we find large contributions from N*(1440)\to Δπ, double-Delta, Δ(1600) \to N*(1440)π, Δ(1600) \to Δπand Δ(1620) \to Δπ. There are also sizeable contributions from Δ\to Δπ, Δ\to Nπ, N \to Δπand nucleon pole at energies close to the threshold. We well reproduce the total cross sections up to beam energies of 2.2 GeV except for the pp\to ppπ^0π^0 channel at energies around 1.1 GeV and our results agree with the existing data of differential cross sections of pp \to ppπ^+π^-, pp \to nnπ^+π^+ and pp \to ppπ^0π^0 which are measured at CELSIUS and COSY.
description: 36 pages, 18 figures
Financial knowledge graph construction
Creators: name: Elhammadi, Sarah
Publisher: name: University of British Columbia
Year: 2020

description: The proliferation of financial news sources reporting on companies, markets, currencies and stocks presents an opportunity for strategic decision making by mining data with the goal of extracting structured representations about financial entities and their inter-relations. These representations can be conveniently stored as (subject, predicate, object) triples in a knowledge graph that can be used drive new in-sights through answering complex queries using high level declarative languages.Towards this goal, we develop a high precision knowledge extraction pipeline tailored for the financial domain. This pipeline combines multiple information ex-traction techniques with a financial dictionary that we built, all working together to produce over 342,000 compact extractions from over 288,000 financial news articles, with a precision of 78% at the top-100 extractions. These extractions are stored in a knowledge graph readily available for use in downstream applications. Our pipeline outperforms existing work in terms of precision, the total number of extractions and the coverage of financial predicates.
Investigating the Effects of Stanniocalcin 2 in an in vitro Stroke Model
Creators: name: Patel, Jainith
name: George, Paul
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: Biology, Stroke, PC12 cells, iPSC-derived neurons, Oxygen and glucose deprivation

description: The investigation of neuroprotective agents against ischemic injury is impeded by the lack of appropriate in vitro models. An in vitro model of ischemic stroke was developed using PC12 and induced pluripotent stem cell (iPSC) derived neuronal cell cultures exposed to oxygen-glucose deprivation (OGD) followed by reoxygenation (24 hours) under atmospheric oxygen levels. Stanniocalcin 2 (STC2) is a protein expressed in the brain and has been shown to play a key role in calcium regulation. This property, along with evidence supporting STC2’s cytoprotective role in cells facing oxidative stress, has suggested it may have a neuroprotective effect during ischemic insult. Live-dead staining from initial experiments showed that iPSC-derived neuronal cells were resistant to cell death under 4, 6, and 8-hour hypoxia at 0.2 - 0.3% oxygen. However, PC12 cells plated on collagen I and collagen IV experienced significant death after OGD relative to control cells. STC2 administration at different doses (4 ng, 20 ng, and 40 ng) yielded no difference in PC12 cell viability between the OGD group and OGD groups supplemented with protein as measured by a fluorometric LDH assay. However, with an increasing dose of STC2, fewer PC12 cells died, suggesting a significant difference in cell survival may occur with the administration of a sufficient dose of STC2. Future experiments will need to assess the effects of higher concentrations of recombinant STC2 administered during OGD and reoxygenation. Stem cell resistance to ischemia-reperfusion injury, cell variability, and lifting of cells after live-dead staining may capture the lack of significant cell death seen in experiments with iPSC-derived neurons. Thus, a more robust neuron differentiation protocol will be followed in the future to produce cells with neuronal properties and less variability.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÑÐ²ÐµÑÐ° Ð¼Ð¾Ð½Ð¸ÑÐ¾ÑÐ¸Ð½Ð³Ð° ÐºÐ»Ð¸Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð¾ÐºÐ°Ð·Ð°Ð½Ð¸Ð¹ Ð² Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÑ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Development of a server for monitoring indoor climate readings
Creators: name: ÐÐ°Ð·Ð°Ð½Ð´Ð¶Ð¸, ÐÐ¸ÑÐ°Ð¸Ð»
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐºÐ»Ð¸Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ
ÐÐÐ¥
ÑÐ±Ð¾Ñ Ð´Ð°Ð½Ð½ÑÑ
Ð±Ð°Ð·Ð° Ð´Ð°Ð½Ð½ÑÑ
ÑÐ¼Ð½Ð¾Ðµ Ð·Ð´Ð°Ð½Ð¸Ðµ
climate parameters
housing and utilities
data collection
database
smart building

description: Ð ÑÐ°Ð¼ÐºÐ°Ñ Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ»Ð¾ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð¾ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ðµ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ðµ Ð´Ð»Ñ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ½ÑÑ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑÐ¾Ð² Ð´Ð»Ñ ÑÐ½ÑÑÐ¸Ñ ÐºÐ»Ð¸Ð¼Ð°ÑÐ¸ÑÐµÂ­ÑÐºÐ¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸Ð¹. Ð Ð¿ÐµÑÐ²Ð¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑÑ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐµÑÂ­Ð½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð·Ð°Ð´Ð°Ð½Ð¸Ñ. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿ÑÐµÐ´Ð¼ÐµÑÐ½Ð¾Ð¹ Ð¾Ð±Â­Ð»Ð°ÑÑÐ¸ Ð¸ Ð°Ð½Ð°Ð»Ð¾Ð³Ð¾Ð². ÐÐ¾ ÑÑÐµÑÑÐµÐ¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑÑ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¸ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð²ÑÐ±Ð¾ÑÐ° ÑÑÐµÐ´ÑÑÐ² ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸. Ð ÑÐµÑÐ²ÐµÑÑÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¾Ð¿Ð¸ÑÑÐ²Ð°ÐµÑÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°Ñ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. Ð Ð¿ÑÑÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¸Ð²Ð¾Ð´ÑÑÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ ÑÐµÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ Ð°Ð¿ÑÐ¾Ð±Ð°ÑÐ¸Ð¸ Ð¿ÑÐ¾Ð´ÑÐºÑÐ°.
description: As part of this work, software was developed for monitoring hardware systems for recording the climatic parameters of premises. The first chapter analyzes the terms of reference. In the second chapter, the analysis of the subject area and analogues is carried out. The third chapter analyzes and justifies the choice of means of implementation. The fourth chapter describes the design result. The fifth chapter contains the results of testing and approbation of the product.
Extended Holomorphic Anomaly in Gauge Theory
Creators: name: Krefl, Daniel
name: Walcher, Johannes
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The partition function of an N=2 gauge theory in the Omega-background satisfies, for generic value of the parameter beta=-eps_1/eps_2, the, in general extended, but otherwise beta-independent, holomorphic anomaly equation of special geometry. Modularity together with the (beta-dependent) gap structure at the various singular loci in the moduli space completely fixes the holomorphic ambiguity, also when the extension is non-trivial. In some cases, the theory at the orbifold radius, corresponding to beta=2, can be identified with an "orientifold" of the theory at beta=1. The various connections give hints for embedding the structure into the topological string.
description: 25 pages
The Fermionic Projector, Entanglement, and the Collapse of the Wave Function
Creators: name: Finster, Felix
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: After a brief introduction to the fermionic projector approach, we review how entanglement and second quantized bosonic and fermionic fields can be described in this framework. The constructions are discussed with regard to decoherence phenomena and the measurement problem. We propose a mechanism leading to the collapse of the wave function in the quantum mechanical measurement process.
description: 17 pages, LaTeX, 2 figures, minor changes (published version)
GABA Antagonism Reduces Sleep Fragmentation and Restores Hourly Sleep in Down Syndrome Model Mice: Pentylenetetrazol as a Therapy for GABAergic Impairment
Creators: name: Artal, Jonathan
name: Heller, H. Craig
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Down syndrome
subject: Sleep
subject: Sleep disorders--Treatment
subject: Sleep-wake cycle
subject: Circadian rhythms
subject: GABA
subject: GABA--Antagonists
subject: Memory
subject: Learning disabilities
subject: Intellectual disability
subject: Pharmacology

description: Evidence from animal models supports that Down syndrome (DS) is characterized by excessive GABAergic inhibition in the hippocampus and cortex. Treatment with pentylenetetrazol (PTZ), a non-specific GABAA receptor antagonist, rescues memory and long-term potentiation in DS mouse models only if delivered during mice’s inactive phase. This time-dependent effect suggests that GABAergic dysfunction impairs processes specific to the inactive phase, such as those under sleep or circadian control. However, almost no work in DS has explored how excess GABA modulates sleep or the extent to which sleep deficits mediate characteristic delays. That paucity is notable given the degree of sleep impairments—which include high sleep fragmentation, shorter NREM bouts, and reduced REM—and their potential to explain phenotypes in DS. Using a well-characterized DS mouse model, I administer a seventeen-day course of PTZ p.o. to clarify interactions between GABAergic dysfunction, sleep, and cognitive impairment in DS. I show that in model mice, PTZ treatment reduces sleep fragmentation, lengthens NREM bouts, and increases sleep amount over nine zeitgeber hours. These gains persist one-month post treatment. My findings indicate that GABAergic transmission disrupts sleep quality in DS model mice and that sleep represents a modifiable factor among deficits. Sleep offers a potential mechanism for the cognitive and developmental delays born of GABAergic dysfunction. GABA antagonists demand study as pharmacotherapies for sleep and memory in DS.
WRF-DART/RTTOV input files for manuscript submittd to GMD Zhou et al., 2022
Creators: name: Yongbo Zhou
name: Yubao Liu
Publisher: name: Zenodo
Year: 2022

description: Namelist for the WRF Preprocessing System (WPS): namelist.wps
 Namelist for WRF-ARW: namelist_nature.input for nature run; namelist_ctrl_exp.input for control and experiment runs.
 Namelist for DART: input-exp-1-2-4-5.nml for cycling data experiments Exp-1, Exp-2, Exp-4, and Exp-5; input-exp-3.nml for cycling data experiment Exp-3; input-exp-6.nml for cycling data experiment Exp-6.
Ticino Turismo
Creators: name: Di Poi, Giona
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2013

description: L’intento di questa ricerca è analizzare l’evoluzione dell’immagine, dei valori e della percezione di un territorio caratterizzato da lingua, clima e cultura mediterranea mescolata a sicurezza, efficenza, organizzazione e appartenenza svizzera. Inizialmente ho individuato alcune statistiche che mostrano il declino nel settore turistico ticinese. C'è inoltre la mancanza di interesse nei confronti della Regione da parte di segmenti giovani. Ripercorrendo la storia dei manifesti e sfociando nell’analisi dell’attuale identità visiva, si vuole generare una coscienza storica in grado di determinare i sostanziali cambiamenti che hanno subito la percezione del territorio e la sua comunicazione promozionale. Si individuano alcuni aspetti critici dell’attuale identità circa i valori che veicolano e la mancanza di una specifica comunicazione di mercato. Questa mancanza, come si vedrà in seguito, è data dall’omologazione alla linea grafica di Svizzera Turismo. L’indagine prosegue nel provare come la concezione dell’identità visiva sia mutata rispetto all’anno in cui è stata concepita l’attuale immagine coordinata dell’Ente. Si affronta perciò un discorso su come questa debba giungere a nuova vita per veicolare valori più legati all’attualità e alle prospettive future del territorio. Specialmente in un futuro che prevede l’apertura di Lac e di AlpTransit. Inizialmente mi ero posto l’obiettivo di creare una nuova immagine coordinata per l’intero Cantone, progetto che ho poi ridimensionato nell’elaborazione di un prototipo di logo e di una campagna promozionale. Un’immagine coordinata di questo tipo, pensata e studiata in ogni minimo dettaglio, necessita molte più menti e molto più tempo di quanto ne avessi a disposizione. Gli scopi che mi sono prefissato sono dunque: creare un nuovo simbolo identitario più profondo e attrarre un pubblico giovane. Da qui è nato l’intento di creare una rottura con un passato di comunicazione standardizzata e monotona per inseguire valori legati ai mutamenti in atto. Questo aspetto deve comportare un totale rinnovamento della comunicazione turistica cantonale che sia in grado di promuovere il Cantone in maniera molto più persuasiva e affascinante. Grazie al mio progetto credo di aver dato a questo tipo di comunicazione un timbro molto più vivace e attrattivo, uscendo completamente dai rigidi schemi di promozione attuati fino ad ora. Come ultima considerazione, posso affermare che l’intero progetto può essenzialmente essere considerato un primo passo verso una via di sviluppo in questa nuova direzione, senza pretendere di essere completo in ogni suo dettaglio pratico. Esso vuole essere la ricerca di una possibilità di rinnovamento, rinvigorimento e consolidamento dell’intera offerta cantonale.
Sistema per la gestione di materiale didattico a supporto di corsi per la formazione Bachelor
Creators: name: Bosia, Luca
Publisher: name: Scuola Universitaria della Svizzera Italiana (SUPSI)
Year: 2022

description: Una delle problematiche principali a cui devono far fronte gli insegnanti di programmazione della Scuola Universitaria Professionale della Svizzera Italiana (SUPSI), è la mancanza di una piattaforma ad hoc per conservare e condividere fra docenti il materiale didattico. Il lavoro di tesi svolto si concentra sulla risoluzione della problematica sopra citata andando a concepire, progettare e sviluppare un’apposita piattaforma web che permetta la gestione avanzata e promuova la condivisione di documentazione fra docenti. Tramite questo sistema si ha, non solo la possibilità di creare, modificare ed eliminare esercizi, rendendone possibile la centralizzazione in un'unica piattaforma, ma anche di mantenerne uno storico d’utilizzo. Ogni domanda può essere inoltre categorizzata utilizzando un sistema di catalogazione basato su keywords scelte dall'utente finale. Grazie a un avanzato sistema di ricerca è possibile filtrare gli esercizi utilizzando molteplici vincoli quali ad esempio il linguaggio di programmazione, il tema trattato,… in modo da facilitare il docente nel fornire esercizi mirati secondo le necessità degli studenti. titolo documento --- One of the main problems for lecturers of programming courses at the University of Applied Sciences and Arts of Southern Switzerland (SUPSI) is the lack of a specific platform for storing and sharing teaching materials among instructors. This thesis work focuses on solving the problem above by conceiving, designing, and developing a dedicated web platform that allows advanced management and promotes sharing documentation between teachers. This system allows you to create, edit and delete exercises. Furthermore, it makes it possible to centralize them in a single platform and to maintain a history of their use. Each question can also be categorized using a cataloging system based on keywords chosen by the end user. Thanks to an advanced search system, it is possible to filter the exercises using multiple constraints (such as programming language, topic, etc.), to facilitate the teacher in providing targeted activities according to the student's needs.
New diterpenoids from the rhizomes of Hedychium forrestii
Creators: name: Wang, Wen-Hui
name: Gao, Jie-Jie
name: Zuo, Xiao-Fei
name: Qin, Xu-Jie
name: Liu, Hai-Yang
name: Zhao, Qing
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: A novel hexanorditerpenoid, hedychin C (1), and a new diterpenoid, hedychin D (2), were isolated from the rhizomes of Hedychium forrestii. Their structures and absolute configurations were unambiguously established by means of extensive spectroscopic data (IR, UV, HRMS, and NMR) and electronic circular dichroism (ECD) calculations. This is the first report of naturally occurring labdane-type hexanorditerpenoid. Compound 1 was proved to have moderate cytotoxicity against XWLC-05 cell line with an IC50 value of 53.6 μM.
Demonstration of a Lightguide Detector for Liquid Argon TPCs
Creators: name: Bugel, L.
name: Conrad, J. M.
name: Ignarra, C.
name: Jones, B. J. P.
name: Katori, T.
name: Smidt, T.
name: Tanaka, H. -K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We report demonstration of light detection in liquid argon using an acrylic lightguide detector system. This opens the opportunity for development of an inexpensive, large-area light collection system for large liquid argon time projection chambers. The guides are constructed of acrylic, with TPB embedded in a surface coating with a matching index of refraction. We study the response to early scintillation light produced by a 5.3 MeV alpha. We measure coating responses from 7 to 8 PE on average, compared to an ideal expectation of 10 PE on average. We estimate the attenuation length of light along the lightguide bar to be greater than 0.5 m. The coating response and the attenuation length can be improved; we show, however, that these results are already sufficient for triggering in a large detector.
Additional file 3 of Next-generation sequencing facilitates differentiating between multiple primary lung cancer and intrapulmonary metastasis: a case series
Creators: name: Liu, Changjiang
name: Liu, Chengang
name: Zou, Xiao
name: Shao, Lin
name: Sun, Ying
name: Guo, Yang
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3.IGV pictures illustrating BRAF p.K601E and V600_K601delinsE mutations.
Metabolome-wide association study of estimated glomerular filtration rates in Hispanics
Creators: name: Lash, J.
name: Boerwinkle, E.
name: Kaplan, R.
name: Yu, B.
name: Sofer, T.
name: Lin, B.M.
name: Cai, J.
name: Daviglus, M.L.
name: Yunes, M.
name: Franceschini, N.
name: Zhang, Y.
name: Qi, Q.
name: Thygarajan, B.
Publisher: name: Elsevier B.V.
Year: 2022

description: Circulating metabolites are by-products of endogenous metabolism or exogenous sources and may inform disease states. Our study aimed to identify the source of variability in the association of metabolites with estimated glomerular filtration rate (eGFR) in Hispanics/Latinos with low chronic kidney disease prevalence by testing the association of 640 metabolites in 3,906 participants of the Hispanic Community Health Study/Study of Latinos. Metabolites were quantified in fasting serum through non-targeted mass spectrometry analysis. eGFR was regressed on inverse normally transformed metabolites in models accounting for study design and covariates. To identify the source of variation on eGFR associations, we tested the interaction of metabolites with lifestyle and clinical risk factors, and results were integrated with genotypes to identify metabolite genetic regulation. The mean age was 46 years, 43% were men, 22% were current smokers, 47% had a Caribbean Hispanic background, 19% had diabetes and the mean cohort eGFR was 96.4 ml/min/1.73 m2. We identified 404 eGFR-metabolite associations (False Discovery Rate under 0.05). Of these, 69 were previously reported, and 79 were novel associations with eGFR replicated in one or more published studies. There were significant interactions with lifestyle and clinical risk factors, with larger differences in eGFR-metabolite associations within strata of age, urine albumin to creatinine ratio, diabetes and Hispanic/Latino background. Several newly identified metabolites were genetically regulated, and variants were located at genomic regions previously associated with eGFR. Thus, our results suggest complex mechanisms contribute to the association of eGFR with metabolites and provide new insights into these associations.
Long-term intertidal community change following mass mortality of Pisaster ochraceus, a keystone marine predator
Creators: name: Chapuis, Micaela
name: Micheli, Fiorenza
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Biology
subject: Keystone species
subject: Pisaster ochraceus
subject: Mytilus californianus
subject: Mussels
subject: Sea Star Wasting Disease
subject: Marine ecology
subject: Predation
subject: Recruitment

description: Beginning in 2013, a Sea Star Wasting Disease epidemic caused a mass mortality event for the ochre sea star (Pisaster ochraceus) and several other sea star species across their entire range of distribution in the California Current region. Because Pisaster ochraceus is a keystone species in rocky intertidal communities and has been shown to control California mussel (Mytilus californianus) populations and prevent their competitive dominance under several settings, thereby maintaining intertidal community diversity, sudden sea star population declines are expected to cause cascading changes on the community. This study tests this prediction and investigates how the natural removal of keystone predation affects the rocky intertidal community in the long term. Previous studies conducted at Hopkins Marine Station, in Monterey Bay, California, in 2014 and 2015 found a limited and spatially heterogeneous expansion of M. californianus following the sea star demise. Field surveys of 18 mussel plots at two sites at Hopkins Marine Station conducted three times a year between 2014 and 2021 show that mussel cover has been increasing since 2014, when there was a peak in mussel recruitment in the area, and that the lower limit of mussel beds has been shifting to lower tidal heights, supporting the hypothesized mussel expansion following predator mass mortality. However, long-term monitoring of the P. ochraceus population at Hopkins Marine Station shows that sea star abundance has been declining since long before 2013. It is therefore likely that changes in M. californianus abundance and distribution are driven by other factors, such as recruitment variability and extreme events in addition to predation pressure. As more mass mortality events are expected under warming conditions in the coming decades, the results of this study, and of future research addressing the impact of multiple stressors on intertidal communities can inform predictions about how the community will change when these events occur.
Resonator/zero-Qubit architecture for superconducting qubits
Creators: name: Galiautdinov, Andrei
name: Korotkov, Alexander N.
name: Martinis, John M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We analyze the performance of the Resonator/zero-Qubit (RezQu) architecture in which the qubits are complemented with memory resonators and coupled via a resonator bus. Separating the stored information from the rest of the processing circuit by at least two coupling steps and the zero qubit state results in a significant increase of the ON/OFF ratio and the reduction of the idling error. Assuming no decoherence, we calculate such idling error, as well as the errors for the MOVE operation and tunneling measurement, and show that the RezQu architecture can provide high fidelity performance required for medium-scale quantum information processing.
description: 11 pages, 5 figures
TRAPing Context- and Region-Specific Ensemble Activity Induced by (±) 3,4- Methylenedioxymethamphetamine
Creators: name: López, Ricardo
name: Heifets, Boris
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: MDMA, fenfluramine, methamphetamine, TRAP, neurobiology, biology, psychiatry

description: (±)3,4-Methylenedioxymethamphetamine (MDMA) has gained considerable traction as a novel therapeutic avenue for treatment-resistant psychiatric illness. Prior research suggests MDMA exerts its prosocial therapeutic effects via discrete nuclei in the striatum. Yet, the anatomical and functional features of these neuronal populations remain unclear. Using transgenic mice enabling activity-dependent neuronal labeling, we examine the region- and context-specific characteristics of neuronal ensembles generated following systemic MDMA delivery. This approach reveals MDMA-induced ensembles in unique segments of the nucleus accumbens (NAc) alongside the extended dorsal endopiriform cortex and claustrum (DEn/Cl). Ensembles in the NAc lateral shell are comparable following drug administration in social or nonsocial environments. By contrast, ensemble densities in the NAc medial shell and DEn/Cl are more robust when MDMA is delivered in social versus nonsocial conditions. This effect is replicated by d-fenfluramine (FEN), a selective serotonin-releasing compound. In describing the anatomical and context-dependent features of distinct MDMA ensembles, we set the foundation for broader functional studies.
2nd Place Floral Arrangement by Mrs. Janice Hoodley James, Flower Show of The Garden Club of East Hampton, August 28, 1934
Creators: name: (:Unas)
Publisher: name: Garden Club of East Hampton
Year: 1934
Subjects: Gardening
Gardens
Social organizations
Organizations
Flower shows
Flower arrangements
East Hampton (N.Y.)

description: This image shows a 2nd place floral arrangement done by Mrs. Janice Hoodley James for a flower show for The Garden Club of East Hampton, August 28, 1934.
The targum (1965:Jan. 5 - 1965:Jan. 14)
Creators: name: No Name Supplied
Publisher: name: Targum Association
Year: 1965

description: Some University historians indicate that the Targum was first published as an annual in 1867, but of this we have no extant evidence. In January 1869, the Targum as we now know it, made its appearance as a monthly paper that concerned itself with student “literary contributions” and college news as well as serving as a vehicle for bringing news to alumni and the general public. The newspaper, which originally was for sale, varied in frequency over the years as did its title (The Targum, Rutgers Targum, Rutgers Daily Targum, and Daily Targum). The newspaper has continuously been published since 1869 with the exception of 19 months during the second world war, between February 1944 and October 1945. The Targum was published by the students of Rutgers College, and later Rutgers University—New Brunswick represented through the years as the Targum Association, Rutgers Targum Association, and Rutgers College Targum. As a student organization, the Targum operated under the oversight of the dean of students and student government but in October 1980, the Targum became an independent college paper.
Poverty, parental depression, parental self-efficacy, social support, and the home learning environment of toddlers : an application of the family stress model
Creators: name: Bendickson, Lindsay
Publisher: name: University of British Columbia
Year: 2020

description: BACKGROUND: Family poverty and the home learning environment (HLE) of toddlers both have significant impacts on children’s future cognitive and academic outcomes. Families facing poverty experience economic hardships and pressures that may lead to difficulty providing a quality HLE. The family stress model was developed to help explain how poverty influences child adjustment through economic pressure and behaviours. There is evidence of its utility in explaining the investments parents make in their children’s learning, but it is not yet known whether the family stress model may be used to predict the HLE of toddlers. In addition, two parental protective factors, parental self-efficacy and social support, may play a role in disrupting the negative effects of depression related to poverty on the HLE. PURPOSE: The purpose of this study was to examine the relationships between economic hardship (low family income), economic pressure (financial difficulty), parental depression, parental self-efficacy, parental social support, and the HLE (shared book reading and story-telling) of toddlers. METHODS: We used logistic regression analysis to perform a secondary data analysis on 423 parent participants of children ages 14-24 months from the Toddler Development Instrument Phase 2 Pilot Implementation Study conducted by the Human Early Learning Partnership at the University of British Columbia. Convenience sampling was used to recruit participants from community-based organization partners across 19 communities in British Columbia, Canada. FINDINGS: After accounting for parental education and child sex, we found: 1) economic hardship and economic pressure were independently negatively associated with the HLE; 2) parental depression was negatively associated with the HLE, and appeared to fully mediate the impact of economic pressure on the HLE; 3) parental self-efficacy was positively associated with the HLE, but social support was not; 5) neither parental self-efficacy nor social support moderated the negative association between parental depression and the HLE. CONCLUSION: The family stress model predicted those families providing a higher quality HLE for toddlers, but did not predict families providing a poorer quality HLE. Economic hardship, economic pressure, parental depression, parental self-efficacy and parental education were associated with the HLE. Practitioners should focus attention on these factors when supporting family HLEs.
Informational derivation of Quantum Theory
Creators: name: Chiribella, G.
name: D'Ariano, G. M.
name: Perinotti, P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Quantum theory can be derived from purely informational principles. Five elementary axioms-causality, perfect distinguishability, ideal compression, local distinguishability, and pure conditioning-define a broad class of theories of information-processing that can be regarded as a standard. One postulate-purification-singles out quantum theory within this class. The main structures of quantum theory, such as the representation of mixed states as convex combinations of perfectly distinguishable pure states, are derived directly from the principles without using the Hilbert space framework.
description: 47 pages, published version + table of contents
Additional file 4 of Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients
Creators: name: Ceyhan-Birsoy, Ozge
name: Jayakumaran, Gowtham
name: Kemel, Yelena
name: Misyura, Maksym
name: Aypar, Umut
name: Jairam, Sowmya
name: Yang, Ciyu
name: Li, Yirong
name: Mehta, Nikita
name: Maio, Anna
name: Arnold, Angela
name: Salo-Mullen, Erin
name: Sheehan, Margaret
name: Syed, Aijazuddin
name: Walsh, Michael
name: Carlo, Maria
name: Robson, Mark
name: Offit, Kenneth
name: Ladanyi, Marc
name: Reis-Filho, Jorge S.
name: Stadler, Zsofia K.
name: Zhang, Liying
name: Latham, Alicia
name: Zehir, Ahmet
name: Mandelker, Diana
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Additional file 4: Fig. S1. Comparison of the cancer type incidence rates in the study cohort to the incidence rates reported by the National Cancer Institute Surveillance, Epidemiology, and End Results program.
Relativistic Effects in Nuclear Matter and Nuclei
Creators: name: van Dalen, E. N. E.
name: Müther, H.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The status of relativistic nuclear many-body calculations of nuclear systems to be built up in terms of protons and neutrons is reviewed. In detail, relativistic effects on several aspects of nuclear matter such as the effective mass, saturation mechanism, and the symmetry energy are considered. This review will especially focus on isospin asymmetric issues, since these aspects are of high interest in astrophysical and nuclear structure studies. Furthermore, from the experimental side these aspects are experiencing an additional boost from a new generation of radioactive beam facilities, e.g. the future GSI facility FAIR in Germany or SPIRAL2 at GANIL/France. Finally, the prospects of studying finite nuclei in microscopic calculations which are based on realistic $NN$ interactions by including relativistic effects in calculations of low momentum interactions are discussed.
description: 57 pages, 16 figures
Publishing difficult? Not with the Bridge plugin!
Creators: name: Bosch, Jonna
Publisher: name: Zenodo
Year: 2023
Subjects: qgis
bridge plugin
metadata
geonetwork
geoserver
mapserver

description: Publishing your map to web services such as GeoServer or MapServer takes quite a bit of effort. At least, without the plug-in GeoCat Bridge for QGIS.

 With Bridge, you no longer have to upload each layer and style separately; instead, you can publish the data, style and metadata all at once. In addition, the StyleViewer translates the style to SLD, MapServer, MapBox or GeoStyler format.

 We will show you the difference between publishing with or without Bridge and how to publish multiple styled map layers at once to GeoServer or MapServer, while at the same time the metadata will be published to a GeoNetwork portal.
The fundamental pro-groupoid of an affine 2-scheme
Creators: name: Chirvasitu, Alexandru
name: Johnson-Freyd, Theo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Category Theory (math.CT)
subject: FOS: Mathematics
subject: 18A30, 18A35, 18F20

description: A natural question in the theory of Tannakian categories is: What if you don't remember $\Forget$? Working over an arbitrary commutative ring $R$, we prove that an answer to this question is given by the functor represented by the étale fundamental groupoid $π_1(\spec(R))$, i.e.\ the separable absolute Galois group of $R$ when it is a field. This gives a new definition for étale $π_1(\spec(R))$ in terms of the category of $R$-modules rather than the category of étale covers. More generally, we introduce a new notion of "commutative 2-ring" that includes both Grothendieck topoi and symmetric monoidal categories of modules, and define a notion of $π_1$ for the corresponding "affine 2-schemes." These results help to simplify and clarify some of the peculiarities of the étale fundamental group. For example, étale fundamental groups are not "true" groups but only profinite groups, and one cannot hope to recover more: the "Tannakian" functor represented by the étale fundamental group of a scheme preserves finite products but not all products.
description: 46 pages + bibliography. Diagrams drawn in TikZ
Field induced spin reorientation and giant spin-lattice coupling in EuFe2As2
Creators: name: Xiao, Y.
name: Su, Y.
name: Schmidt, W.
name: Schmalzl, K.
name: Kumar, C. M. N.
name: Price, S.
name: Chatterji, T.
name: Mittal, R.
name: Chang, L. J.
name: Nandi, S.
name: Kumar, N.
name: Dhar, S. K.
name: Thamizhavel, A.
name: Brueckel, Th.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have studied a EuFe2As2 single crystal by neutron diffraction under magnetic fields up to 3.5 T and temperatures down to 2 K. A field induced spin reorientation is observed in the presence of a magnetic field along both the a and c axes, respectively. Above critical field, the ground state antiferromagnetic configuration of Eu$^{2+}$ moments transforms into a ferromagnetic structure with moments along the applied field direction. The magnetic phase diagram for Eu magnetic sublattice in EuFe2As2 is presented. A considerable strain ($\sim$0.9%) is induced by the magnetic field, caused by the realignment of the twinning structure. Furthermore, the realignment of the twinning structure is found to be reversible with the rebound of magnetic field, which suggested the existence of magnetic shape-memory effect. The Eu moment ordering exhibits close relationship with the twinning structure. We argue that the Zeeman energy in combined with magnetic anisotropy energy is responsible for the observed spin-lattice coupling.
description: 5 pages, 4 figures
Chiral Thermodynamics of Dense QCD
Creators: name: Sasaki, Chihiro
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We show a phase diagram of a two-flavored parity doublet model on top of the nuclear matter ground state within the mean field approximation. An exotic phase with unbroken center symmetry of chiral group is also discussed. When crossing this phase boundary the baryon number susceptibility exhibits a characteristic feature.
description: 4 pages, 2 figures, to appear in proceedings of "New Frontiers in QCD 2010 (NFQCD10)", Kyoto, Japan, 18 January to 19 March, 2010
Development and validation of a RASS-related nomogram to predict the in-hospital mortality of neurocritical patients: a retrospective analysis based on the MIMIC-IV clinical database
Creators: name: Gu, Shenyan
name: Wang, Yuqin
name: Ke, Kaifu
name: Tong, Xin
name: Gu, Jiahui
name: Zhang, Yuanyuan
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy

description: Richmond agitation-sedation scale (RASS) is a simple and widely used tool for evaluating sedation and agitation in adult ICU patients. Early deep sedation has been shown to be an important independent predictor of death, however, studies on the role of RASS in the prognostic assessment of neurocritical patients are lacking. The purpose of this study was to investigate the relationship between RASS and in-hospital mortality in neurocritical patients, and to develop and validate an effective predictive model based on this. This was a retrospective study of neurocritical patients from a large clinical database. A total of 2651 patients were collected, including general demographic characteristics, past medical history, biochemical test data and physical examination within 24 h of admission, and related medical records. Univariate and multivariate logistic regression analyses were used to screen out significant variables. Finally, 11 significant predictors were included into the logistic regression to establish the nomogram. The area under the curve (AUC) of the nomogram was 0.9087(0.8950–0.9224) and the corrected c index was 0.9043, which gave the model better discriminatory ability compared with critical care related scales, such as SOFA and SAPSII scores. Besides, tools including calibration curve, decision curve analysis (DCA), and clinical impact curve (CIC) were used to verify that the model had good discrimination, calibration, and clinical applicability. RASS score was an independent prognostic predictor of in-hospital death in neurocritical patients, and patients who are deeply sedated have a worse prognosis. RASS-related nomogram could be applied to predict the prognosis of neurocritical patients and to take effective intervention measures in early stage.
Early Cretaceous provenance-depositional systems and volcano-sedimentary responses to strike-slip faulting in southern Jilin and eastern Liaoning provinces, NE China: a case study of the Tonghua Basin
Creators: name: Zhou, Yang
name: Cheng, Rihui
name: Shen, Yanjie
name: Xu, Zhongjie
name: Liu, Guodong
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Understanding how the sedimentary responses adapt to the structural styles of fault basins in the strike-slip fault systems is one of the key goals of basin analysis. Variability of volcanic and epiclastic provenance-depositional systems and tectonic controls of the Lower Cretaceous Hengtongshan Formation in the Tonghua Basin are crucial to determine the evolution of the fault basins and wrench tectonics in southern Jilin and eastern Liaoning provinces (SJELP), NE China. Study of volcanism-induced sedimentation, composition plot, and depositional systems elucidates the sequence stratigraphy and volcano-sedimentary responses to wrench tectonics based on cores, outcrop sections, and seismic profiles of the Tonghua Basin. Two types of provenance-depositional systems (volcanic and epiclastic) were reconstituted using eight lithofacies and seven lithofacies associations. Of the lithofacies, six pyroclastic lithofacies and two epiclastic lithofacies were identified based on compositions, textures, and sedimentary structures. The presence of these lithofacies in different vertical successions was described as different lithofacies associations to interpret depositional processes and sedimentary environments. Depositional-system maps of the three sequences in the Hengtongshan Formation and analysis of structural framework indicate that volcanism and sedimentation were controlled by wrench faulting. Statistical analysis of rock compositions reveals that the deposition of the Hengtongshan Formation shows mixed contribution from both the volcanic and granitic fragments. Triangular compositional plots of detrital composition suggest a diverse provenance by straddling the litho-feldspatho-quartzose (lFQ), feldspatho-litho-quartzose (fLQ), feldspatho-quartzo-lithic (fQL), and quartzo-feldspatho-lithic (qFL) fields, indicating that the sources were derived from uplifted basement blocks and volcanic eruptions in a rift basin related to strike-slip faulting. The Tonghua Basin developed as a wrench-fault basin on the east side of Dunhua–Mishan Fault systems (DMF). This model for the Tonghua Basin can be used to understand the Liuhe Basin in the DMF and other Early Cretaceous basins in adjacent areas.
A new approach to quantum measurement problem: cluster separability
Creators: name: Hajicek, Petr
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The paper describes a solution to the problem of quantum measurement that has been proposed recently. The literal understanding of the basic rule of quantum mechanics on identical particles violates the cluster separation principle and so leads to difficulties. A proposal due to Peres of how such difficulties could be removed is reformulated and extended. Cluster separability leads to a locality requirement on observables and to the key notion of separation status. Separation status of a microsystem is shown to change in preparation and registration processes. The indispensability of detectors plays an important role. Changes of separation status are alterations of kinematic description rather than some parts of dynamical trajectories and so more radical than 'collapse of the wave function'. Textbook quantum mechanics does not provide any information of how separation status changes run, hence new rules must be formulated. This enables to satisfy the objectification requirement for registrations. To show how the ideas work, a simplified model of registration apparatus is constructed.
description: 15 pages, no figures. Rule 2 generalized, some references corrected. Based on the talk at Fifth International Workshop DICE2010, Castiglioncello (Tuscany), September 13--17, 2010