cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Counting the exponents of single transfer matrices
Creators: name: Molinari, Luca Guido
name: Lacagnina, Giuseppe
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 15A09, 15A15, 15A18, 15B52

description: The eigenvalue equation of a band or a block tridiagonal matrix, the tight binding model for a crystal, a molecule, or a particle in a lattice with random potential or hopping amplitudes: these and other problems lead to three-term recursive relations for (multicomponent) amplitudes. Amplitudes n steps apart are linearly related by a transfer matrix, which is the product of n matrices. Its exponents describe the decay lengths of the amplitudes. A formula is obtained for the counting function of the exponents, based on a duality relation and the Argument Principle for the zeros of analytic functions. It involves the corner blocks of the inverse of the associated Hamiltonian matrix. As an illustration, numerical evaluations of the counting function of quasi 1D Anderson model are shown.
description: 9 pages, 2 figures
Transforming growth factor-beta1 is a negative modulator of adult neurogenesis
Creators: name: Wachs, Frank-Peter
name: Winner, Beate
name: Couillard-Despres, Sebastien
name: Schiller, Thorsten
name: Aigner, Robert
name: Winkler, Jürgen
name: Bogdahn, Ulrich
name: Aigner, Ludwig
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: 610 Medizin

description: Transforming growth factor (TGF)-beta1 has multiple functions in the adult central nervous system (CNS). It modulates inflammatory responses in the CNS and controls proliferation of microglia and astrocytes. In the diseased brain, TGF-beta1 expression is upregulated and, depending on the cellular context, its activity can be beneficial or detrimental regarding regeneration. We focus on the role of TGF-beta1 in adult neural stem cell biology and neurogenesis. In adult neural stem and progenitor cell cultures and after intracerebroventricular infusion, TGF-beta1 induced a long-lasting inhibition of neural stem and progenitor cell proliferation and a reduction in neurogenesis. In vitro, although TGF-beta1 specifically arrested neural stem and progenitor cells in the G0/1 phase of the cell cycle, it did not affect the self-renewal capacity and the differentiation fate of these cells. Also, in vivo, TGF-beta1 did not influence the differentiation fate of newly generated cells as shown by bromo-deoxyuridine incorporation experiments. Based on these data, we suggest that TGF-beta1 is an important signaling molecule involved in the control of neural stem and progenitor cell proliferation in the CNS. This might have potential implications for neurogenesis in a variety of TGF-beta1-associated CNS diseases and pathologic conditions.
Archean crustal evolution constrained by strontium isotopes in apatite and uranium-lead geochronology and trace element geochemistry of zircon
Creators: name: Emo, Robert Bernard
Publisher: name: University of British Columbia
Year: 2018

description: Archean continents were the nuclei for crustal growth and large volumes of continental crust appear to have been produced during the Archean. Much of the preserved Archean crust is of tonalite-trondhjemite-granodiorite (TTG) composition and it is argued that this made up the bulk of Earth’s earliest crust. Other models involve a bulk mafic crust that was very different to the modern crust. New data are therefore needed to test and refine these models and determine how continents were first formed. The Rb-Sr isotopic system provides a potentially powerful proxy for crustal composition yet it has thus far been underutilized in studies on early crustal evolution due to its susceptibility to re-equilibration. Overcoming this issue requires new analytical approaches to micro-sample ancient Sr-rich minerals, such as apatite, that may retain primary 87Sr/86Sr signatures. In this thesis study, a novel method in laser-ablation multi-collector inductively coupled plasma mass spectrometry (LA-MC-ICPMS) was applied to apatite from TTG complexes of different Archean age. The first area of focus was the Acasta Gneiss Complex, Northwest Territories, which contains the oldest known terrestrial rocks. Apatite inclusions within ca. 3.7 Ga zircon host grains were subjected to Sr isotope analysis by LA-MC-ICPMS. The initial 87Sr/86Sr values of these inclusions are identical within error and are different from values obtained from altered matrix apatite. Combining the 87Sr/86Sr results with information on the protolith and source-extraction age yields estimates for the range of source Rb/Sr and suggests that an evolved Hadean source was involved in the formation of the Acasta Gneiss Complex. The Sr isotope LA-MC-ICPMS method was also applied to matrix apatite from TTG of the ca. 3.6 Ga Bastar Craton, India, and the 3.0-2.8 Ga Kvanefjord Block, Greenland. The radiogenic 87Sr/86Sr signatures from these apatite grains also require a high Rb/Sr crustal source. This suggests that enriched crustal vestiges played a role in the formation of TTG crust.
Kappa-Minkowski differential calculi and star product
Creators: name: Mercati, Flavio
name: Sitarz, Andrzej
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present the star-product algebra of the kappa-deformation of Minkowski space and the formulation of Poincare covariant differential calculus. We use these tools to construct a twisted K-cycle over the algebra and a twisted cyclic cocycle.
description: Based on talk at the Corfu Summer Institute on Elementary Particles and Physics - Workshop on Noncommutative Field Theory and Gravity, September 8-12, 2010, Corfu Greece
Optical variability of the ultraluminous X-ray source NGC 1313 X-2
Creators: name: Impiombato, D.
name: Zampieri, L.
name: Falomo, R.
name: Grisé, F.
name: Soria, R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We analyzed the longest phase-connected photometric dataset available for NGC 1313 X-2, looking for the ~6 day modulation reported by Liu et al. (2009). The folded B band light curve shows a 6 days periodicity with a significance slightly larger than 3 sigma. The low statistical significance of this modulation, along with the lack of detection in the V band, make its identification uncertain.
description: 4 pages, 2 figures. Accepted for publication in the Astronomische Nachrichten (Astronomical Notes), to appear in the proceedings of the conference "Ultra-Luminous X-ray sources and Middle Weight Black Holes" (Madrid, May 24-26, 2010)
Nokardioseinfektion einer Gefäßendoprothese
Creators: name: Babilas, P.
name: Scherer, K.
name: Landthaler, M.
name: Ehrenstein, B.
name: Szeimies, R.-M.
Publisher: name: Universität Regensburg
Year: 2007
Subjects: subject: Meropenem; Granulombildung; Nokardiose; Bakteriämie; Gefäßendoprothese; Granuloma; Nocardiosis; Bacteremic infection; Vascular prosthesis
subject: 610 Medizin

description: Eine 61-jährige Patientin stellte sich mit rötlich lividen, subkutanen Knötchen im Bereich des rechten Beines vor. Über die letzten 10 Tage bestand Fieber bis 40°C, seit 2 Monaten Mattigkeitsgefühl. Vier Monate zuvor war ein femuropoplitealer Bypass implantiert worden. Unter der Verdachtsdiagnose einer Weichteilinfektion nach Implantation einer infizierten Endoprothese wurde die Patientin stationär aufgenommen und antibiotisch behandelt. Unter der initialen Antibiose war der Lokalbefund der Patientin progredient, darüber hinaus entwickelten sich septische Abszessherde in den großen Gelenken des rechten Beines, in der Leber sowie im ZNS. Erst eine mikrobiologische Kultur mit langer Bebrütungszeit von Abstrichmaterial erbrachte den Nachweis einer Infektion mit den langsam wachsenden Norkardien ssp. Daraufhin konnte die Patientin zielgerichtet mit Meropenem über 6 Monate behandelt werden. Unter dieser Therapie stellte sich eine restitutio ad integrum ein.
 A 61-year-old woman presented with purple-red subcutaneous nodules on her right leg. She had experienced fever up to 40 degrees C for the past 10 days and felt generally weak over the last two months. Four months earlier, a vascular graft had been implanted in her right femoral artery. Based on the diagnosis of skin infection due to implantation of an infected prosthesis, she was hospitalized and treated with an antibiotic regime. During the initial antibiotic treatment, the symptoms deteriorated, and she developed joint, hepatic and CNS abscesses. Finally, a microbiologic culture with an extended incubation time revealed the diagnosis of an infection with the slowly growing bacterium Nocardia ssp. Hereupon the patient was treated purposeful with Meropenem over six months. This treatment resulted in complete recovery.
Strömungscharakteristischer Vergleich dezentraler Lüftungsauslegungen in Wohngebäuden mittels CFD-Simulation
Creators: name: Röder, Tim Alexander
name: Mathis, Paul
name: Müller, Dirk
Publisher: name: RWTH Aachen University
Year: 2018

description: Symposium Wohnungslüftung 2018, Stuttgart, Germany, 8 Oct 2018 - 8 Oct 2018
Defining high-fat-diet rat models: metabolic and molecular effects of different fat types
Creators: name: Buettner, R.
name: Parhofer, K. G.
name: Woenckhaus, M.
name: Wrede, C. E.
name: Kunz-Schughart, L. A.
name: Schölmerich, J.
name: Bollheimer, L. C.
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: 610 Medizin

description: High-fat (HF)-diet rodent models have contributed significantly to the analysis of the pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly between different studies. Here, we have systematically compared the metabolic and molecular effects of different HF with varying fatty acid compositions. Male Wistar rats were fed HF diets (42% energy; fat sources: HF-L - lard; HF-O - olive oil; HF-C - coconut fat; HF-F - fish oil). Weight, food intake, whole-body insulin tolerance and plasma parameters of glucose and lipid metabolism were measured during a 12-week diet course. Liver histologies and hepatic gene expression profiles, using Affymetrix GeneChips, were obtained. HF-L and HF-O fed rats showed the most pronounced obesity and insulin resistance; insulin sensitivity in HF-C and HF-F was close to normal. Plasma omega-3 polyunsaturated fatty acid (omega-3-PUFA) and saturated fatty acid (C(12)-C(14), SFA) levels were elevated in HF-F and HF-C animals respectively. The liver histologies showed hepatic steatosis in HF-L, HF-O and HF-C without major inflammation. Hepatic SREBP1c-dependent genes were upregulated in these diets, whereas PPARalpha-dependent genes were predominantly upregulated in HF-F fed rats. We detected classical HF effects only in diets based on lard and olive oil (mainly long-chain, saturated (LC-SFA) and monounsaturated fatty acids (MUFA)). PUFA- or MC-SFA-rich diets did not induce insulin resistance. Diets based on LC-SFA and MUFA induced hepatic steatosis with SREBP1c activation. This points to an intact transcriptional hepatic insulin effect despite resistance to insulin's metabolic actions.
JOINT MPH PROGRAMS ADDIS CONTINENTAL INSTITUTE OF PUBLIC HEALTH BAHIR DAR CAMPUS ASSESSMENT OF HEALTH CARE SEEKING AND ITS ASSOCIATED FACTORS AMONG RURAL AND URBAN MOTHER OF BURIE WOREDA, WEST GOJJAM, AMHARA REGION, ETHIOPIA
Creators: name: HAFFA, BELAY
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2010

description: No abstract available for this resource
History and evidence regarding hydrostatic shock
Creators: name: Courtney, Michael
name: Courtney, Amy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: This paper reviews the history and evidence related to remote wounding effects of ballistic pressure waves imparted to tissue by the impact of a bullet. Such remote effects are often referred to as hydraulic or hydrostatic shock. In spite of considerable published evidence and a long history, some medical professionals continue to regard the ability of a bullet to injure tissue that is not directly crushed or stretched as mythical (Jandial R, Reichwage B, Levy M, Duenas V, Sturdivan L. Ballistics for the neurosurgeon. Neurosurgery. 2008:62:472-480.) Early references to these effects date to the 19th century; however, compelling experimental support and medical findings in human case studies did not become available until the late 20th and early 21st century.
ICAM-1 and VCAM-1 expression following aneurysmal subarachnoid hemorrhage and their possible role in the pathophysiology of subsequent ischemic deficits
Creators: name: Rothoerl, Ralf Dirk
name: Schebesch, Karl-Michael
name: Kubitza, Marion
name: Woertgen, Chris
name: Brawanski, Alexander
name: Pina, Ana-Luisa
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Adhesion molecules; Intercellular adhesion molecule-1; Vascular cell adhesion molecule-1; Subarachnoid hemorrhage; Vasospasm; Ischemic neurological defi cit, delayed
subject: 610 Medizin

description: BACKGROUND: The pathophysiology of ischemic cerebral lesions following aneurysmal subarachnoid hemorrhage (SAH) is poorly understood. There is growing evidence that inflammatory reactions could be involved in the pathogenesis of such delayed occurring ischemic lesions. The aim of this study was to evaluate adhesion molecules with regard to these lesions following SAH. METHODS: Serum and cerebrospinal fluid (CSF) samples were taken daily from 15 patients up to day 9 after SAH and evaluated for intercellular adhesion molecule-1 (ICAM-1) and vascular adhesion molecule-1 (VCAM-1). RESULTS: CSF and serum samples correlated well during nearly the whole time course (p < 0.0001). A secondary increase in ICAM-1 and VCAM-1 in the serum and CSF correlated with an increase in flow velocity in the transcranial Doppler (p > 0.0001 and p < 0.007) but not to a delayed lesion in the CT scan. CONCLUSION: We believe that inflammatory processes are involved in the pathogenesis of cerebral vasospasm but they might only be a part of a multifactorial pathogenesis.
(E)-metanicotine hemigalactarate (TC-2403-12) inhibits IL-8 production in cells of the inflamed mucosa
Creators: name: Spoettl, Tanja
name: Paetzel, Christine
name: Herfarth, Hans
name: Bencherif, Merouane
name: Schoelmerich, Juergen
name: Greinwald, Roland
name: Gatto, Gregory J.
name: Rogler, Gerhard
Publisher: name: Universität Regensburg
Year: 2007
Subjects: subject: Nicotine derivatives; Ulcerative colitis; Interleukin-8; Mucosal inflammation; Macrophages; Epithelial cells
subject: 610 Medizin

description: BACKGROUND: Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to determine the effectiveness of TC-2403-12 in the inhibition of TNF- and lipopolysaccharide (LPS)-induced cell activation. METHODS: Colonic epithelial cells (CEC), monocytes (MM6), granulocytes, and the intestinal epithelial cell line HT-29 were stimulated with TNF and LPS and treated with TC-2403-12. IL-8 secretion in the cell supernatants and NF-kappaB activation were determined by ELISA. Apoptosis was quantified by flow cytometry. RESULTS: In MM6 cells, IL-8 secretion was significantly decreased to 30% of control after TC-2403-12 treatment, with best results after pretreatment for 24 h. This decrease in cell activation was not due to apoptosis and was not mediated by inhibition of NF-kappaB activation. IL-8 production in neutrophils and primary CEC also tended to be decreased after TC-2403-12 treatment. TC-2403-12 had no influence on IL-8 secretion of HT-29 cells. CONCLUSION: TC-2403-12 effectively inhibited TNF- and LPS-induced IL-8 production in different cell types. No toxic effects occurred at the concentrations used. Preincubation of cells with TC-2403-12 showed the best effects.
Exploration of hyperfine interaction between constituent quarks via eta productions
Creators: name: He, Jun
name: Yuan, S. G.
name: Xu, H. S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: In this work, the different exchange freedom, one gluon, one pion or Goldstone boson, in constituent quark model is investigated, which is responsible to the hyperfine interaction between constituent quarks, via the combined analysis of the eta production processes, $π^{-}p\rightarrowηn$ and $γp\rightarrowηp$. With the Goldstone-boson exchange, as well as the one-gluon or one-pion exchange, both the spectrum and observables, such as, the differential cross section and polarized beam asymmetry, are fitted to the suggested values of Particle Data Group and the experimental data. The first two types of exchange freedoms give acceptable description of the spectrum and observables while the one pion exchange can not describe the observables and spectrum simultaneously, so can be excluded. The experimental data for the two processes considered here strongly support the mixing angles for two lowest S11 sates and D13 states as about -30 and 6 degree respectively.
description: 7 pages, 4 figures, 4 tables
TEACHERS’ ATTITUDE TOWARDS INCLUSIVE EDUCATION A PHENOMENOLOGICAL EXPLORATION: THE CASE OF 2 HIGH SCHOOLS IN DILLA TOWN IN GEDIO ZONE, ETHIOPIA
Creators: name: ABABU TESHOME AYALEW (PhD)
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2019

description: There has been a paradigm shift globally regarding the adoption of inclusive education policies and procedures. However, teachers still have varying views, anxieties, and preconceived misconceptions about the successful implementation of inclusive education practices in the general education classroom. Having this in mind, the researcher was motivated to conduct the study in 2 purposefully selected high schools in Dilla town to investigate how far teacher’s developed positive attitude in implementing inclusive education in the study area. This study utilized a qualitative approach to provide an informative exploration of teachers’ attitudes toward inclusive education and its implementation, possible factors that influence teachers’ attitude and recommendations for promoting best practices in inclusive education. Data was collected utilizing semi-structured interviews from eight teachers selected from 2 high schools in Dilla town. Convenience sampling was utilized, because of feasibility and access to the participants. The results of the study revealed that teachers generally had positive attitudes toward integration/inclusion. However, lack of funding, administrative support and minimal opportunities for training and development were identified as negative influential factors regarding teachers’ attitude towards inclusive education. The researcher concludes that teachers’ attitude plays a pivotal role in the successful implementation of inclusive education. On this premise, this study was conducted to determine the attitude of high school teachers in the Dilla town regarding inclusive education. Further to determine possible influential factors regarding their attitude. The study revealed that high school teachers within the Dilla town generally had a positive attitude towards inclusive education. The researcher suggests that the more sustainability that educators have for inclusion, the more effective its implementation would be. Therefore, it is probable that the modification and implementation of future legislation and policies were to increase greater awareness of the needs and rights of special needs children. To this end, it is paramount that once these elements have been established, curriculum specialists and other stakeholders would revisit the Federal curriculum to ensure the infusion of inclusive education.
A SITUATIONAL ANALYSIS OF VULNERABILITY OF STUDENTS WITH DISABILITY TO HIV/AIDS PROSPECTIVE OF DILLA AND HAWASA UNIVERSITIES
Creators: name: Ababu Teshome & Ali Sani
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2019

description: The main objective of the study was to explore the situation of students with physical challenge with specific to the level of their knowledge, attitude and accessibility to information on HIV/AIDS.  It was also to suggest recommendations that an inclusive resource centre is to be organized in which students with physical challenge are accommodated.   To conduct this study, 43 respondents for questionnaire through random and 16 students for focus group discussion through purposeful sampling techniques were selected.   Both quantitative and qualitative research approach was employed either to carry out the data collection or analyze the data.  To obtain the relevant information, the researchers developed Questionnaires which consisted of 20 items and 2 focus group discussion sessions in which 15 semi-structured questions were prepared.    As a result, the study has come up with findings that: Majority (96%) students with physical challenge have high level of knowledge on HIV/AIDS. Both groups of students with visual and orthopedic impairment were found differentiating the difference between HIV and AIDS. Poverty and opportunistic disease which may cause people to be vulnerable to HIV/AIDS are also well understood by participants. They have also very good understanding about female with disability that they have double burden as result of having HIV and their disability. Despite such group of people have high level of knowledge,  many of them (85%) of them did not take HIV blood test and do not use Condoms consistently while they practice sexual enter-course.  (85%) of the respondents and all focus group discussion participants reported that HIV/AIDS related activities in the Universities are exclusive to the potential and unique need of students with physical challenge. Thus the research is concluded that students with visual and orthopedic challenge found learning in Dilla and Hawasa Universities have high level of knowledge on HIV/AIDS. The main barriers why students with physical challenge were not mainstreamed in HIV/AIDS focused programs emanated from wrongly formulated stereotypes, prejudice and environmental factors. Thus to address the unique of need of such group of the population, all stakeholders working on HIV/AIDS should revisit their projects to make sure that all citizens are equally to be addressed with specific to prevention and controlling of the spread of HIV/AIDS among the risk group.
Mapping the carbonate alteration footprint of the Cortez Hills Carlin-type gold deposit, Nevada using carbon-oxygen isotopes, and geochemistry as a vectoring tool
Creators: name: Herron, Christopher Stephen
Publisher: name: University of British Columbia
Year: 2018

description: The Cortez Hills deposit is located along the Battle-Mountain Eureka Trend in North-Central Nevada and is a world-class Carlin-type (CTD) gold deposit. Visible and cryptic alteration associated with mineralization were used to define footprints, alteration haloes, mineralization targets and fluid pathways. Approximately 2,500 carbon and oxygen isotope analyses from a mm- to m-scale using core, chips, pulped rock and surface samples together with geology and geochemistry provided an integrated dataset for evaluating fluid transport and alteration in the Cortez Hills plumbing system. The Cortez Hills plumbing system was described using calcite veins. Timing of calcite veins were based on crosscutting relationships relative to alteration and mineralization events. Three main vein stages were identified which includes ten vein types and two stylolite events. Cross-cutting relationships were supported by vein physical characteristics to improve identification. Calcite veins at Cortez Hills have distinct physical and chemical characteristics that can be identified with a variety of methods. Chemical characteristics were used to understand the processes that formed veins. V2 veins associated with Carlin fluids could be a significant fluid pathway contributing to the hydrothermal plumbing system. Calcite veins have the potential to be used as an exploration tool for Carlin systems. Invisible alteration was described using carbon and oxygen stable isotopes, and Carlin pathfinder elements (As, Au, Hg, Sb, and Tl) as a vectoring tool. Oxygen isotopes represented the most far-field detectable feature of CTDs and were used to define the cryptic carbonate alteration of Cortez Hills. Defining thresholds for carbon and oxygen isotopes, and pathfinder elements were integral to map alteration haloes (lower threshold), define mineralization targets (upper threshold) and map fluid flow pathways. Isotopes and pathfinder elements were described in order of greatest distance travelled outboard of economic gold orezones and utilized as a vectoring tool for alteration and mineralization: 18O>As>Hg>Sb>Tl-13C>Au. The defined 18O deposit footprint (lower threshold) was >3.5km and the pathfinder element alteration halo was 2.2km in size. The defined 18O mineralization target (upper threshold) was 1km in width and 0.6km in height.
The Morphology of the Expanding Ejecta of V2491 Cygni (2008 N.2)
Creators: name: Ribeiro, V. A. R. M.
name: Darnley, M. J.
name: Bode, M. F.
name: Munari, U.
name: Harman, D. J.
name: Steele, I. A.
name: Meaburn, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Determining the evolution of the ejecta morphology of novae provides valuable information on the shaping mechanisms in operation at early stages of the nova outburst. Understanding such mechanisms has implications for studies of shaping for example in proto-Planetary Nebulae. Here we perform morpho-kinematical studies of V2491 Cyg using spectral data to determine the likely structure of the ejecta and its relationship to the central system and shaping mechanisms. We use Shape to model different morphologies and retrieve their spectra. These synthetic spectra are compared with observed spectra to determine the most likely morphology giving rise to them, including system inclination and expansion velocity of the nova ejecta. We find the best fit remnant morphology to be that of polar blobs and an equatorial ring with an implied inclination of 80$^{+3}_{-12}$ degrees and an maximum expansion velocity of the polar blobs of 3100$^{+200}_{-100}$ km/s and for the equatorial ring 2700$^{+200}_{-100}$ km/s. This inclination would suggest that we should observe eclipses which will enable us to determine more precisely important parameters of the central binary. We also note that the amplitude of the outburst is more akin to the found in recurrent nova systems.
description: 9 pages, 7 figures, accepted for publication in MNRAS
Behandlungspfade – praktikable Hilfe für den behandelnden Arzt?
Creators: name: Audebert, F. X.
name: Büttner, R.
name: Hartmann, P.
name: Schölmerich, J.
name: Bollheimer, L. C.
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Leitlinie; Behandlungspfad; Klinischer Algorithmus; Tuberkulose; Guideline; Clinical pathway; Clinical algorithm; Tuberculosis
subject: 610 Medizin

description: Zusammenfassung Leitlinien, Behandlungspfade und klinische Algorithmen sind heutzutage beliebte Instrumente zur Qualitätssicherung und Ökonomisierung von ärztlicher Arbeit. Diese Begriffe werden allerdings häufig nur unscharf voneinander abgegrenzt. Leider verkomplizieren medizinische Standards oft den Verfahrensablauf und erleichtern die Entscheidungsfindung im klinischen Alltag kaum. In unserer Klinik werden praktikable standardisierte Vorgehensweisen in Form strukturierter Textdokumente verfasst. Diese sollen einerseits als unmittelbare Entscheidungshilfe für den Arzt am Krankenbett und andererseits als ärztlich vorgegebener Grundriss für die Ausarbeitung betriebsorganisatorisch ausgerichteter Behandlungspfade auf interdisziplinärer Ebene dienen. Am Beispiel der Abklärung bei Verdacht auf Tuberkulose werden Gliederung und Inhalt dieses an unserer Klinik etablierten Textdokuments dargestellt.
 Guidelines, clinical pathways and clinical algorithms are popular instruments nowadays to ensure quality as well as the economic efficiency of medical work. These terms themselves, however, are frequently defined only in a diffuse way. Thus, medical standard procedures often complicate clinical workflows more than to facilitate decision making in everyday life. In our department, feasible standardized approaches have been generated in the form of structured text documents, which on the one hand can aid clinical decision making at the bedside and on the other hand serve as medical sketches for the generation of operational treatment paths on an interdisciplinary level. Structure and content of such an instructional text are exemplified here using our standardized document for the diagnostic approach when tuberculosis is suspected.
Nair-Tenenbaum bounds uniform with respect to the discriminant
Creators: name: Henriot, Kevin
Publisher: name: arXiv
Year: 2011
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: A common problem in analytic number theory is to bound the sum of an arithmetic function over a set of integers. Nair and Tenenbaum found a very general bound that applies to short sums of a multivariable arithmetic function over polynomial values, under certain standard conditions on the growth of that function. Their bound features an implicit dependency on the discriminant of the relevant polynomial. In our paper we obtain an analogous bound with an explicit dependency on the discriminant, which is optimal in the discriminant aspect.
description: 20 pages
Indirect MR arthrography of the shoulder: use of abduction and external rotation to detect full- and partial-thickness tears of the supraspinatus tendon
Creators: name: Herold, Thomas
name: Bachthaler, Maike
name: Hamer, Okka W.
name: Hente, Reiner
name: Feuerbach, Stefan
name: Fellner, Claudia
name: Strotzer, Michael
name: Lenhart, Markus
name: Paetzel, Christian
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: 610 Medizin

description: PURPOSE: To evaluate prospectively the accuracy of indirect magnetic resonance (MR) arthrography for supraspinatus tendon tears during neutral positioning or abduction and external rotation (ABER) and neutral positioning. MATERIALS AND METHODS: Informed consent was obtained in all patients, and the study was approved by the institutional review board. Indirect MR arthrography of the shoulder was performed in 51 symptomatic patients (14 female, 37 male; mean age, 47 years) in the neutral position (set 1) and in the neutral and ABER positions (set 2). Two readers independently interpreted both sets, and diagnoses were compared with arthroscopic findings. Diagnostic accuracy was calculated, and 95% confidence intervals were used to detect significant differences between sets. Diagnostic confidence was recorded by using a three-level confidence score. Differences between sets were evaluated by using the Wilcoxon signed rank test. Interobserver agreement was determined separately for each set and for all diagnoses, full-thickness tears, and partial-thickness tears. RESULTS: For full-thickness tears, there was no benefit to reading set 2. For reader 1, sensitivity and specificity were 95% and 100%, respectively, for set 1 and 100% and 100%, respectively, for set 2. For reader 2, sensitivity and specificity were 80% and 100%, respectively, for set 1 and 100% and 100%, respectively, for set 2. For partial-thickness tears, sensitivity was significantly higher after reading set 2. For reader 1, sensitivity and specificity were 71% and 88%, respectively, for set 1 and 93% and 100%, respectively, for set 2. For reader 2, sensitivity and specificity were 50% and 88%, respectively, for set 1 and 86% and 94%, respectively, for set 2. For both readers, diagnostic confidence for partial-thickness tears was significantly higher after reading set 2. After the interpretation of set 2, kappa values increased from 0.35 to 1.00 for full-thickness tears and from 0.12 to 0.63 for partial-thickness tears. CONCLUSION: Indirect MR arthrography with supplementary images obtained with patients in the ABER position significantly improved sensitivity and increased diagnostic confidence for partial-thickness tears of the supraspinatus tendon. Interobserver agreement was improved for both full- and partial-thickness tears.
Additional file 1 of Seroprevalence, spatial distribution, and social determinants of SARS-CoV-2 in three urban centers of Chile
Creators: name: Vial, Pablo
name: González, Claudia
name: Icaza, Gloria
name: Ramirez-Santana, Muriel
name: Quezada-Gaete, Rubén
name: Núñez-Franz, Loreto
name: Apablaza, Mauricio
name: Vial, Cecilia
name: Rubilar, Paola
name: Correa, Juan
name: Pérez, Claudia
name: Florea, Andrei
name: Guzmán, Eugenio
name: Lavín, María-Estela
name: Concha, Paula
name: Nájera, Manuel
name: Aguilera, Ximena
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Computational Biology

description: Additional file 1. Table S1. Sample and population distribution in the three cities. Table S2. Population seroprevalence of SARS-CoV-2 antibodies by city and sociodemographic variables. Chile 2020. Table S3. Seroprevalence of SARS-CoV-2 antibodies according to contact history and clinical characteristics by city. Chile 2020. Table S4. Frequency and type of symptoms and presence of SARS-CoV-2 antibodies by city. Chile 2020. Table S5. Seroprevalence of SARS-CoV-2 antibodies according to self-reported chronic conditions. Chile 2020. Table S6. Seroprevalence of SARS-CoV-2 antibodies according to self-reported chronic conditions by city. Chile 2020.
A multiscale autocorrelation function for anisotropy studies
Creators: name: Scuderi, M.
name: De Domenico, M.
name: Insolia, A.
name: Lyberis, H.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In recent years many procedures have been proposed to check the anisotropy of a dataset. We present a new simple procedure, based on a scale dependent approach, to detect anisotropy signatures in a given distribution with particular attention to small dataset. The method provides a good discrimination power for both large and small datasets, even in presence of strong contaminating isotropic background. We present some applications to simulated datasets of events to investigate statistical features of the method and present and inspect its behavior under both the null or the alternative hypothesis.
description: 10 pages, 6 figures, conference proceeding
How do current approaches to communicating ambiguity in risk estimates influence decisions?
Creators: name: Hicklin, James Gregory
Publisher: name: University of British Columbia
Year: 2018

description: Background: Uncertain outcomes are an unavoidable fact of medicine. First-order uncertainty (e.g. “10 in 100 people can expect an outcome in the next year”) has well-established guidelines as to how it should be best presented, but it is not clear if and how to present second-order uncertainty, referred to as ambiguity (e.g. “10 [95% CI 5,15] in 100”). Objectives: To explore the ways in which ambiguity in risk is currently being described to patients by (1) identifying existing presentation techniques and evidence for their potential impact on decision-making, (2) investigating how presentation techniques influence decision-related outcomes, including intention, trust, worry, decisional uncertainty, risk perception, knowledge and preference, and (3) determining which techniques should be investigated further. Methods: The literature on current techniques to present ambiguity was systematically reviewed through an electronic search of the Medline/PubMed database, and an existing database of patient decision support interventions. The influence of each identified communication technique was evaluated by the design and implementation of a web-survey in a hypothetical atrial fibrillation vignette. Results: Nine distinct presentation techniques were identified as having been used in the past, and were shown to influence decision-making outcomes. Of these techniques, the visual and textual range techniques were found to result in change in intention (in both directions) which was statistically significant, while other techniques decreased trust, increased decisional uncertainty, and resulted in greater knowledge. Conclusions: Techniques that resulted in the worst knowledge of the range in risk scores tended to be the ones that were preferred by participants. Yet, without good knowledge of risks involved with different medical options, informed consent, and value-based decisions are challenging. Findings from this work indicate that some techniques for presenting uncertainty, such as the visual and textual range techniques, impact various psychometric outcomes related to decision-making, including intention to take oral anticoagulation, trust in risk estimates, decisional uncertainty and knowledge of ambiguity. Further research should focus on testing the influence of these techniques on decision-making related outcomes.
Towards a more specific therapy: targeting nonmelanoma skin cancer cells
Creators: name: Szeimies, R. M.
name: Karrer, S.
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: 610 Medizin

description: Epithelial cancers of the skin, e.g. basal cell carcinoma and squamous cell carcinoma, are the most common tumours in humans with increasing incidence. Hence the development of new therapeutic strategies is of utmost interest. For many years the most often used conventional therapies for these diseases were surgical procedures such as curettage and electrodesiccation, excision or, with so far the best outcome in terms of remission rates, micrographic surgery. Other ablative treatment modalities are cryotherapy, radiation therapy or the use of lasers (Er:YAG, CO(2)). All those above-mentioned treatments have in common that they are quite unspecific and do not target the tumour itself or its environment, thus leading to unwanted effects in the surrounding tissue such as scar formation or other cosmetically disfiguring events. Therefore, the development of novel, more pathogenesis-based therapies such as the use of retinoids, cyclooxygenase inhibitors, topical immunomodulators, inhibitors of the sonic-hedgehog signalling pathway or photodynamic therapy are challenging new approaches.
High-speed measurement of rifle primer blast waves
Creators: name: Courtney, Michael
name: Courtney, Amy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences

description: This article describes a method and results for direct high-speed measurements of rifle primer blast waves employing a high-speed pressure transducer located at the muzzle to record the blast pressure wave produced by primer ignition. Our key findings are: 1) Most of the primer models tested show 5-12% standard deviation in the magnitudes of their peak pressure. 2) For most primer types tested, peak pressure magnitudes are well correlated with measured primer masses so that significant reductions in standard deviation are expected to result from sorting primers by mass. 3) A range of peak pressures from below 200 psi to above 500 psi is available in different primer types.
On the algebraic independence of Hamiltonian characteristic classes
Creators: name: Gal, Swiatoslaw
name: Kedra, Jarek
name: Tralle, Aleksy
Publisher: name: arXiv
Year: 2010
Subjects: subject: Symplectic Geometry (math.SG)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We prove that Hamiltonian characteristic classes defined as fibre integrals of powers of the coupling class are algebraically independent for generic coadjoint orbits.
description: 9 pages, no figures
Decaying Dark Matter in the Supersymmetric Standard Model with Freeze-in and Seesaw mechanims
Creators: name: Kang, Zhaofeng
name: Li, Tianjun
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Inspired by the decaying dark matter (DM) which can explain cosmic ray anomalies naturally, we consider the supersymmetric Standard Model with three right-handed neutrinos (RHNs) and R-parity, and introduce a TeV-scale DM sector with two fields ϕ_{1,2} and a $Z_3$ discrete symmetry. The DM sector only interacts with the RHNs via a very heavy field exchange and then we can explain the cosmic ray anomalies. With the second right-handed neutrino N_2 dominant seesaw mechanism at the low scale around 10^4 GeV, we show that ϕ_{1,2} can obtain the vacuum expectation values around the TeV scale, and then the lightest state from ϕ_{1,2} is the decay DM with lifetime around \sim 10^{26}s. In particular, the DM very long lifetime is related to the tiny neutrino masses, and the dominant DM decay channels to μand τare related to the approximate μ-τsymmetry. Furthermore, the correct DM relic density can be obtained via the freeze-in mechanism, the small-scale problem for power spectrum can be solved due to the decays of the R-parity odd meta-stable states in the DM sector, and the baryon asymmetry can be generated via the soft leptogensis.
description: 24 pages,3 figures
Additional file 1 of Processing speed and working memory are predicted by components of successful aging: a HUNT study
Creators: name: Bosnes, Ingunn
name: Bosnes, Ole
name: Stordal, Eystein
name: Nordahl, Hans M.
name: Myklebust, Tor Å.
name: Almkvist, Ove
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. Panel A. Rotated component matrix for eight WAIS-III cognitive tests (panel A). Loadings > 0.60 are in bold type. Panel B. Rotated component matrix for eight WMS-III memory tests (panel B). Loadings > 0.60 are in bold type.
Differentiation of hematopoietic progenitor cells towards the myeloid and B-lymphoid lineage by hepatocyte growth factor (HGF) and thrombopoietin (TPO) together with early acting cytokines
Creators: name: Grassinger, Jochen
name: Mueller, Gunnar
name: Zaiss, Matthias
name: Kunz-Schughart, Leoni A.
name: Andreesen, Reinhard
name: Hennemann, Burkhard
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: CD34; differentiation; hematopoietic progenitor cells; hepatocyte growth factor; thrombopoietin; lymphopoiesis
subject: 610 Medizin

description: Objectives: The effect of stem cell factor (SCF), flt3-ligand (FL), and interleukin (IL)-3 (SF3) in combination with hepatocyte growth factor (HGF), thrombopoietin (TPO), and Hyper-IL-6 on maintenance and differentiation of early human peripheral blood-derived progenitor cells was investigated. Methods: Single sorted CD34(+) 38(-) cells were cultured with various combinations of these growth factors in order to identify the most effective cytokine combination. Then, lineage-depleted cells were stimulated for 7 d in bulk culture before they were assessed by flow cytometry and in functional assays. Results: The highest number of clones in the single-cell assay was obtained after culture with SF3 + TPO + HGF. Cell expansion with SF3 + TPO + HGF yielded an increase of the total cell number (11-fold), the number of CD34(+) cells (sevenfold), colony forming cells (CFC; 13-fold), granulocytes (CD15/66b(+); 45-fold) and B-cells (CD19/20(+); 55-fold). However, the number of long-term culture initiating cells (LTC-IC) decreased from 779 +/- 338 per 1 x 10(5) CD34(+) cells on day 0 to 253 +/- 115 on day 7. In parallel, the number of pluripotent mouse repopulating cells decreased by the factor 11, and no significant change in the proportion of human myeloid or lymphoid cells found in the mouse bone marrow was noted. Conclusion: The observation that mature cells of different lineages are generated and that transplantable multipotent hematopoietic cells are lost during culture suggests the differentiation of early hematopoietic progenitors toward lineage committed cells by the tested cytokines. The detection of cells expressing B-lymphoid markers after culture indicates a possible role in the propagation of B-cells.
ADDRESSING ICT IMPLEMENTATION CHALLENGES IN RICE EXTENSION SERVICES IN BENUE AND NIGER STATES.
Creators: name: Ahmed, Umar
Publisher: name: AYDEN JOURNAL
Year: 2024
Subjects: Extension, Food security, Information Communication Technologies, Rice Farmers.

description: This study was carried out to investigate the constraints to application of selected information and communication (ICT) technologies in extension service delivery among rice farmers and extension workers in Benue and Niger States, Nigeria. Adopting a multistage sampling technique in four stages, 202 respondents were selected to form the sample size. Data were collected using a well-structured questionnaire, and analyzed using both descriptive and inferential statistics, particularly frequency, percentage, mean, standard deviation, Mann-Whiney, Chi-square and Factor analysis. Findings revealed that there was no significant relationship between level of knowledge in application of selected ICT by the respondents X2 Cal = 2.86 < X2 Tab = 5.991) at 0.05 level of probability. Results also indicated that there were three categories of constraints, namely socio-economic constraints (Factor 1), environmental constraints (Factor 2) and administrative constraints (Factor 3). Provision of internet network; procurement and installation of ICTs and supportive services in all ADPs should be assured. Also, the constraints to application of ICT should be addressed by the government
Additional file 1 of Curcumin and zinc co-supplementation along with a loss-weight diet can improve lipid profiles in subjects with prediabetes: a multi-arm, parallel-group, randomized, double-blind placebo-controlled phase 2 clinical trial
Creators: name: Karandish, Majid
name: Mozaffari-khosravi, Hassan
name: Mohammadi, Seyed Mohammad
name: Cheraghian, Bahman
name: Azhdari, Maryam
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: Additional file 1: Table A1. The biochemical measurements of the participants at the baseline. Table A2. Comparison of changes in liver enzymes, anthropometry measurements, physical activity, and dietary intake between the groups. Table A3. Results of the pairwise comparisons of BMI, weight, and serum lipid profiles for significant ANCOVA.