cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort.
Creators: name: Kulyté, Agné
name: Lundbäck, Veroniqa
name: Lindgren, Cecilia M
name: Luan, Jian'an
name: Lotta, Luca A
name: Langenberg, Claudia
name: Arner, Peter
name: Strawbridge, Rona J
name: Dahlman, Ingrid
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Adipocytes
Gene Expression
Subcutaneous
Genetic Variants
Lipolysis

description: OBJECTIVES:Lipolysis, hydrolysis of triglycerides to fatty acids in adipocytes, is tightly regulated, poorly understood, and, if perturbed, can lead to metabolic diseases including obesity and type 2 diabetes. The goal of this study was to identify the genetic regulators of lipolysis and elucidate their molecular mechanisms. METHODS:Adipocytes from abdominal subcutaneous adipose tissue biopsies were isolated and were incubated without (spontaneous lipolysis) or with a catecholamine (stimulated lipolysis) to analyze lipolysis. DNA was extracted and genome-wide genotyping and imputation conducted. After quality control, 939 samples with genetic and lipolysis data were available. Genome-wide association studies of spontaneous and stimulated lipolysis were conducted. Subsequent in vitro gene expression analyses were used to identify candidate genes and explore their regulation of adipose tissue biology. RESULTS:One locus on chromosome 19 demonstrated genome-wide significance with spontaneous lipolysis. 60 loci showed suggestive associations with spontaneous or stimulated lipolysis, of which many influenced both traits. In the chromosome 19 locus, only HIF3A was expressed in the adipocytes and displayed genotype-dependent gene expression. HIF3A knockdown in vitro increased lipolysis and the expression of key lipolysis-regulating genes. CONCLUSIONS:In conclusion, we identified a genetic regulator of spontaneous lipolysis and provided evidence of HIF3A as a novel key regulator of lipolysis in subcutaneous adipocytes as the mechanism through which the locus influences adipose tissue biology.
Writing media art into (and out of) history
Creators: name: Tofts, Darren
Publisher: name: Swinburne
Year: 2024

description: This paper will review the context of the development of interactive media art within Australia in the 1990s. It is particularly interested in the conditions that enable arts practices to galvanize into an arts culture. Such conditions include publishing, the role of criticism and debate, funding, advocacy and the curation of focussed and dedicated exhibitions. The paper will seek to ask some questions answers as to why the conditions of an emerging media arts culture in the 1990s have virtually lost momentum. And why, ultimately. the very notion of media arts has become annexed as a minor moment in the history of the moving image.
Studies Towards Synthesis of Tetracyclic Core of Daphmanidin A-Type Alkaloids
Creators: name: Vishwakarma Singh
name: Beauty Das
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Chemistry
Biotechnology
Cell Biology
Biochemistry

description: A stereoselective approach to spiro-annulated bicyclo[2.2.2]octane ring system related to the tetracyclic skeleton of daphmanidin A-type alkaloids is described. Ring-closing metathesis, Wacker oxidation and aldol condensation are key features of our approach. An interesting steric effect on aldol condensation has also been observed.
Generic queer: literary history after visibility, 1980-2020
Creators: name: Roberts, Kelly
Publisher: name: No Publisher Supplied
Year: 2023

description: Each chapter in this dissertation examines works of queer fiction that developed in relation to other genres: poetry, theater and performance art, journalism, and autobiography. As I will show, a multi-generic perspective is necessary for understanding the context in which the novels under consideration were produced. But such a perspective also provides for a more compelling and socially honest account of how writing happens. Novel history is often somewhat out of sync with the nonlinear and messy lived experience of thinking and talking and writing. This is perhaps even more true for the work of queer fiction, as a burgeoning social and sexual subcultural scene brought together writers, artists, performers, intellectuals, and workers of all stripes who might otherwise have had little in common. In such social scenes, queer writers found themselves in active conversation with artists working across a range of genres and media, and many queer novelists developed dynamic new literary forms that corresponded less to accepted literary categories and more to conversations within queer subcultures. Through sociological analyses of production, circulation, and reception, I show how taking the non-normative and coalitional impulse of the term “queer” seriously allows us to reassess the ways we classify and value literature. This reassessment, in turn, helps to reveal the way that queer aesthetics have also significantly shaped the development of contemporary fiction more broadly.
Integrating Nonnative Species in Niche Models to Prioritize Native Fish Restoration Activity Locations along a Desert River Corridor
Creators: name: Walsworth, Timothy E.
name: Budy, Phaedra
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences

description: The efficient allocation of restoration resources is critical for the effective conservation of species. Here, we developed an ecological niche model to predict the response of three imperiled desert fishes to potential restoration actions along the longitudinal gradient of a desert river. The San Rafael River, Utah, is home to a complex of three endemic fishes (Flannelmouth Sucker Catostomus latipinnis, Bluehead Sucker C. discobolus, and Roundtail Chub Gila robusta; referred to as the “three species”). Like many Colorado River basin tributaries, the river is overallocated for human use, has experienced extensive physical degradation, and is now home to several nonnative fish species. To determine the factors most limiting to the three species, we first fit random forest models to fish CPUE and habitat data. We next combined these models with a longitudinal habitat survey and modeled nonnative species abundance to predict the continuous distribution of the three species in the lower San Rafael River, under current conditions and following simulated restoration. Nonnative fishes were important negative predictors of Flannelmouth Sucker and Bluehead Sucker relative abundance, and broadscale habitat variables were important positive predictors for all of the three species. Each of the three species was predicted to experience a significant increase in abundance following simulated eradication of nonnative fishes. Responses to simulated reach-specific habitat restoration were dependent on the reach restored, demonstrating that the choice of restoration location is critical. Nonnative species removal and restoring degraded reaches near already suitable habitat were predicted to be the most beneficial to the three species. Ecological niche models developed at the river scale, and incorporating both physical and biotic predictor variables, can provide spatially explicit information that appropriately parallels the spatial distribution of the needs of endemic fishes and can facilitate effective management and conservation decisions.Received December 2, 2014; accepted February 20, 2015
Comparison of single-point and continuous sampling methods for estimating residential indoor temperature and humidity
Creators: name: Johnston, James D.
name: Magnusson, Brianna M.
name: Eggett, Dennis
name: Collingwood, Scott C.
name: Bernhardt, Scott A.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Computational Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology
subject: Medicine
subject: Biophysics

description: ABSTRACTResidential temperature and humidity are associated with multiple health effects. Studies commonly use single-point measures to estimate indoor temperature and humidity exposures, but there is little evidence to support this sampling strategy. This study evaluated the relationship between single-point and continuous monitoring of air temperature, apparent temperature, relative humidity, and absolute humidity over four exposure intervals (5-min, 30-min, 24-hrs, and 12-days) in 9 northern Utah homes, from March – June 2012. Three homes were sampled twice, for a total of 12 observation periods. Continuous data-logged sampling was conducted in homes for 2–3 wks, and simultaneous single-point measures (n = 114) were collected using handheld thermo-hygrometers. Time-centered single-point measures were moderately correlated with short-term (30-min) data logger mean air temperature (r = 0.76, β = 0.74), apparent temperature (r = 0.79, β = 0.79), relative humidity (r = 0.70, β = 0.63), and absolute humidity (r = 0.80, β = 0.80). Data logger 12-day means were also moderately correlated with single-point air temperature (r = 0.64, β = 0.43) and apparent temperature (r = 0.64, β = 0.44), but were weakly correlated with single-point relative humidity (r = 0.53, β = 0.35) and absolute humidity (r = 0.52, β = 0.39). Of the single-point RH measures, 59 (51.8%) deviated more than ±5%, 21 (18.4%) deviated more than ±10%, and 6 (5.3%) deviated more than ±15% from data logger 12-day means. Where continuous indoor monitoring is not feasible, single-point sampling strategies should include multiple measures collected at prescribed time points based on local conditions.
Collective dynamics of vortices in trapped Bose-Einstein condensates
Creators: name: Simula, Tapio
Publisher: name: Swinburne
Year: 2024

description: We have calculated collective-mode spectra for three-dimensional, rotating Bose-Einstein condensates in oblate harmonic traps using the microscopic Bogoliubov-de Gennes field theory. For condensates with Nv vortices, Nv Kelvin-Tkachenko-mode branches are obtained. The features of these modes are compared with those predicted by a classical point-vortex model. We have created movies to visualize the motion of the vortices corresponding to the Kelvin-Tkachenko waves.
The choice, implementation and benefits of corporate social responsibility initiatives
Creators: name: Bedggood, Rowan
name: Nicholson, Lorrae
Publisher: name: Swinburne
Year: 2024

description: Organisations are under increasing pressure to favourably impact the communities in which they operate, and accordingly, are adopting a range of Corporate Social Responsibility (CSR) initiatives. This study sought the views and opinions of managers responsible for CSR in five large organisations across five key industries in Australia to determine whether they adopt a broad or narrow range of CSR initiatives and whether they perceive any competitive advantage (benefit) by having adopted their current initiatives. Findings indicate that most organisations partner with an NGO to help implement and manage the CSR initiative and tend to choose more social than eco-environmental initiatives. Competitive advantages were commonly perceived as being improved reputation or brand image.
Group work as a vehicle for engaging students into the process of broadening perspectives and building inter-cultural skills
Creators: name: Rhamdhani, Akbar
name: Salehi, Kay
name: Wong, Yat
name: Kapoor, Ajay
Publisher: name: Swinburne
Year: 2024

description: This paper describes a trial project designed to broaden students' cultural perspectives by incorporating a forced mixed group assignment in a third year mechanical engineering unit. Students were formed into groups that included at least one international student in each group. They were required to complete a group work project on a real-world problem that transcended international boundaries. The student groups were encouraged to consider that the international student might have expert local knowledge useful for the project. Following the trial project, all students were asked to comment on whether they had a heightened awareness and curiosity about other cultures, reflect on any communication issues they personally needed to address, and whether the experience had encouraged them to confidently engage cross-culturally. As with previous research, it was concluded that getting students to engage inter-culturally is difficult. It requires teaching staff to intervene by creating a conducive environment and provide assistance throughout the process to foster the intercultural engagement.
Research through industrial design: industrial design in the context of an Australian Cooperative Research Centre
Creators: name: Melles, Gavin
name: Ginters, Lotars
name: Kuys, Blair
Publisher: name: Swinburne
Year: 2024

description: The creative arts and industries, including design, are currently legitimating to higher education and funding bodies how project work, documentation of research process and critical reflection is the appropriate mix for scholarship in these fields. Central to industrial design is the role of making and products in the design research process although this emphasis may not be shared by the fields with which industrial design works. Cooperative Research Centers (CRCs) are contexts where science, design and industry collaborate offering unique opportunities to examine interdisciplinary similarity and difference and an environment for design research to prove to government and higher education the legitimacy and quality of its work. Drawing on evidence from two recent doctoral projects in CRC industry/university collaboration for Wood Innovation this paper analyses the design, science encounter and its consequences for knowledge production in the project text. The authors further argue that only a balance of prototype, process and reflection can help establish the academic and disciplinary status of design, itself a precondition for convincing the institutional skeptics of the current and future legitimacy and value of the creative fields.
Crinecerfont: First Approval
Creators: name: Lee, Arnold
Publisher: name: Adis Journals
Year: 2025
Subjects: Medicine

description: Declarations
Funding The preparation of this review was not supported by any external funding.
Authorship and Conflict of interest During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Arnold Lee is a contracted employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content.
Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability not applicable
Additional information about this Adis Drug Review can be found here.
Abstract
Crinecerfont (CRENESSITY™) is a corticotropin releasing factor type 1 (CRF1) receptor antagonist developed by Neurocrine Biosciences for the treatment of classic congenital adrenal hyperplasia (CAH) in adult and paediatric patients. In patients with classic CAH, circulating levels of adrenocorticotropic hormone (ACTH), androstenedione and 17-hydroxyprogesterone are elevated, which traditionally has required supraphysiologic doses of glucocorticoids to manage. As a CRF1 receptor antagonist, crinecerfont acts by reducing systemic ACTH secretion to subsequently decrease elevated levels of steroid precursors and adrenal androgens, thereby reducing the dosage of glucocorticoids required to manage androgen levels in patients. This article summarizes the milestones in the development of crinecerfont leading to this first approval as an adjunctive treatment to glucocorticoid replacement to control androgens in adults and paediatric patients aged ≥ 4 years with classic CAH.
© Springer Nature Switzerland AG 2025
title: ÐÐµÐ³ÐºÐ¸Ðµ ÑÑÐ°Ð»ÐµÐ±ÐµÑÐ¾Ð½Ð½ÑÐµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸
title: Ð¼Ð¾Ð½Ð¾Ð³ÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: Ð ÑÐ±Ð°ÐºÐ¾Ð², ÐÐ»Ð°Ð´Ð¸Ð¼Ð¸Ñ
name: Ð¡ÐµÐ»Ð¸Ð²ÐµÑÑÑÐ¾Ð², ÐÐ½Ð°ÑÐ¾Ð»Ð¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2025
Subjects: ÐÐµÑÐ¾Ð½Ð½ÑÐµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸
Ð¡ÑÐ°Ð»ÑÐ½ÑÐµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸
ÐÐµÐ½Ð¾Ð±ÐµÑÐ¾Ð½
Ð¿Ð°Ð½ÐµÐ»Ð¸
ÑÑÐµÐ½Ð¾Ð²ÑÐµ Ð¿Ð°Ð½ÐµÐ»Ð¸
Ð¿Ð°Ð½ÐµÐ»Ð¸ Ð¿ÐµÑÐµÐºÑÑÑÐ¸Ñ

description: ÐÐµÐ³ÐºÐ¸Ðµ ÑÑÐ°Ð»ÐµÐ±ÐµÑÐ¾Ð½Ð½ÑÐµ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ (ÐÐ¡ÐÐ) â ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¸ Ð¸Ð· ÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÐºÐ°ÑÐºÐ°ÑÐ°, ÐºÐ°Ðº Ð¿ÑÐ°Ð²Ð¸Ð»Ð¾ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÑÑÐ°Ð»ÑÐ½ÑÑ ÑÐ¾Ð½ÐºÐ¾ÑÑÐµÐ½Ð½ÑÑ ÑÐ¾Ð»Ð¾Ð´Ð½Ð¾Ð³Ð½ÑÑÑÑ Ð¾ÑÐ¸Ð½ÐºÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð¿ÑÐ¾ÑÐ¸Ð»ÐµÐ¹, Ð·Ð°Ð¿Ð¾Ð»Ð½ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð² Ð½ÐµÑÑÐµÐ¼Ð½Ð¾Ð¹ Ð»Ð¸ÑÑÐ¾Ð²Ð¾Ð¹ Ð¾Ð¿Ð°Ð»ÑÐ±ÐºÐµ Ð¼Ð¾Ð½Ð¾Ð»Ð¸ÑÐ½ÑÐ¼ Ð¿ÐµÐ½Ð¾Ð±ÐµÑÐ¾Ð½Ð¾Ð¼ Ð¿Ð¾Ð½Ð¸Ð¶ÐµÐ½Ð½Ð¾Ð¹ Ð¿Ð»Ð¾ÑÐ½Ð¾ÑÑÐ¸, ÐºÐ°Ðº Ð¿ÑÐ°Ð²Ð¸Ð»Ð¾ Ð¾Ñ 200 Ð´Ð¾ 600 ÐºÐ³/Ð¼3. Ð ÐºÐ½Ð¸Ð³Ðµ Ð¿ÑÐ¸Ð²Ð¾Ð´ÑÑÑÑ Ð¼ÐµÑÐ¾Ð´Ñ ÑÐ°ÑÑÐµÑÐ° Ð½Ð° Ð¿ÑÐ¾ÑÐ½Ð¾ÑÑÑ Ð¸ Ð¶ÐµÑÑÐºÐ¾ÑÑÑ Ð½ÐµÑÑÑÐ¸Ñ Ð¸ Ð¾Ð³ÑÐ°Ð¶Ð´Ð°ÑÑÐ¸Ñ ÐÐ¡ÐÐ, Ð¿ÑÐ¸Ð²Ð¾Ð´Ð¸ÑÑÑ Ð¿Ð¾Ð´ÑÐ¾Ð±Ð½Ð¾Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð¸Ñ ÑÐµÐ¿Ð»Ð¾ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ², ÐºÐ¾ÑÑÐ¾Ð·Ð¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÐ¾Ð¹ÐºÐ¾ÑÑÐ¸ Ð¾Ð³Ð½ÐµÑÑÐ¾ÐºÐ¾ÑÑÐ¸ Ð¸ Ð³Ð¾ÑÑÑÐµÑÑÐ¸. ÐÐ½Ð¸Ð³Ð° Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð° Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð¼Ð°Ð³Ð¸ÑÑÑÐ°Ð½ÑÐ¾Ð² Ð¸ Ð°ÑÐ¿Ð¸ÑÐ°Ð½ÑÐ¾Ð², Ð¾Ð±ÑÑÐ°ÑÑÐ¸ÑÑÑ Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÐ¼ 08.04.01 Â«Ð¡ÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð¾Â», 08.05.01 Â«Ð¡ÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð¾ ÑÐ½Ð¸ÐºÐ°Ð»ÑÐ½ÑÑ Ð·Ð´Ð°Ð½Ð¸Ð¹ Ð¸ ÑÐ¾Ð¾ÑÑÐ¶ÐµÐ½Ð¸Ð¹Â» Ð¸ 08.06.01 Â«Ð¢ÐµÑÐ½Ð¸ÐºÐ° Ð¸ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð°Â» Ð² ÐºÐ°ÑÐµÑÑÐ²Ðµ Ð´Ð¾Ð¿Ð¾Ð»Ð½Ð¸ÑÐµÐ»ÑÐ½Ð¾Ð¹ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÑ Ð´Ð»Ñ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð½Ð°ÑÑÐ½Ð¾-Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð¸ Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¸Ñ Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. ÐÐ¾Ð½Ð¾Ð³ÑÐ°ÑÐ¸Ñ ÑÐ°ÐºÐ¶Ðµ Ð±ÑÐ´ÐµÑ Ð¿Ð¾Ð»ÐµÐ·Ð½Ð° Ð¿ÑÐµÐ¿Ð¾Ð´Ð°Ð²Ð°ÑÐµÐ»ÑÐ¼, Ð½Ð°ÑÑÐ½ÑÐ¼ ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ°Ð¼ Ð¸ ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸ÑÑÐ°Ð¼, Ð·Ð°Ð½Ð¸Ð¼Ð°ÑÑÐ¸Ð¼ÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ°Ð¼Ð¸ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾Ð¹ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¸ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÐ½ÑÑ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð¹ Ð·Ð´Ð°Ð½Ð¸Ð¹ Ð¸ ÑÐ¾Ð¾ÑÑÐ¶ÐµÐ½Ð¸Ð¹.
How are engineering graduates prepared to work in a culturally changing world?
Creators: name: Rhamdhani, Akbar
name: Salehi, Kay
name: Wong, Yat
name: Kapoor, Ajay
name: Vakhguelt, Anatoli
Publisher: name: Swinburne
Year: 2024

description: Engineering graduates need to be able to 'perform professionally/socially in an international and multicultural environment' (OECD). They need to be aware of the sociocultural, economic, geographical aspects in the particular environment they will be contributing to. This paper examines how an Australian university engineering faculty, in their local and offshore campuses preparing engineering graduates to be adaptable in an international and culturally diverse environment. Data generated from surveys carried out at the two campuses highlighted some interesting responses from both local and international students. This paper shares their responses to questions relating to how they currently view their profession in the global environment and how well they feel they are being prepared to work in diverse culturally mixed global environments. The paper will conclude with a description on how one discipline group is planning to trial some class work changes that is intended to enhance cross-cultural engagement among students.
title: “Don’t Sell Your Neighbor” Class, Urban Politics, and Grassroots Mobilizations in Old Town Istanbul
Creators: name: Topçu, Berra
Publisher: name: University of Massachusetts Amherst
Year: 2015
Subjects: subject: Anthropology
subject: FOS: Sociology

description: The city has become the site of global movements and class struggles in the past decade. Since the Gezi uprising in the summer of 2013 in Istanbul, grassroots movements are emerging from the space of the neighborhood and the megacity in response to failures of urban governance at the level of metropolitan and local municipalities. Based on a five-month ethnographic study in a central district of Istanbul, I use participant-observation, semi-structured interviews, and media and document analysis to explore what common ground can be found in the context of: 1) official city assemblies of the Istanbul Metropolitan Municipality; 2) activist-led urban resistance assemblies; and 3) grassroots mobilizations in an urban poor neighborhood by the historic city walls. From Henri Lefebvre (2009) to David Harvey (2012), the “right to the city” framework needs to be reworked to ground the city and the grassroots (Castells 1983) as the emergent site of class struggles as well as class solidarities. Following Ida Susser and Stéphane Tonnelat’s (2013) typology of the three urban commons, this paper explores how ethnographically grounded accounts can be given from the specificity and generality of urban struggles, based on perspectives by expert and non-expert subjects, including residents, activists, reporters, planners, and officials. I argue for attending to the small-scale of the neighborhood and the large-scale of the megacity to build and make sense of urban social movements from the bottom-up.
Reverse engineering: a formative method of research
Creators: name: Kuys, Blair
name: Jackson, Simon
name: Melles, Gavin
name: Anderson, Lyndon
Publisher: name: Swinburne
Year: 2024

description: Design meets people's needs. In order to advance design for future needs, we can learn from our past â- what has worked well and what has not. The act of reverse engineering existing products helps identify successes and mistakes that may have occurred over the service life of a product. Reverse engineering is a method of disassembling existing products to better understand their construction and manufacture. It is an analytical process of observation and documentation used to improve the design of existing products. Knowledge learnt is then considered, developed and applied to create better products. Reverse engineering was an important component of the doctoral research study and design outcome referred to in this paper. The design outcome for this study is a timber window frame: a casement window designed as a product that exhibits the fundamental qualities of formative research highlighting the importance of reverse engineering practices to advance existing products, giving strength to timber as a sustainable material of choice for the window frame industry. Comparison studies of new and old window frames have been conducted to visually represent reverse engineering methods of research. This reverse engineering method identifies poorly constructed products, while design advancements are also developed from this process. In the case of a timber window frame, it has been valuable research to reverse engineer older products to observe deteriorated areas. These areas have deteriorated from moisture build-up leading to rot and decay from fungal attack over a prolonged period. This is the major weakness of timber used in outdoor applications. Observing this in an old window and understanding why these problems have occurred has led to improved design solutions for innovative future products. Manufactured timber window frame, which is the result of this doctoral research, gives highest importance to energy-efficiency, sustainable materials, quality hardware and innovative design solutions to prevent rot and decay during the service life of the product. This window acts as an exemplar product for other window frame types and other timber products intended for outdoor use. The specific style of window, a casement window, was manufactured as it best highlights the areas of innovation incorporated into the design outcome derived from reverse engineering methods.
Corrigendum to: “Effective interventions for preventing work relatedphysical health complaints in nursing students and novice nurses: A systematic review” [Nurse Educ. Pract. 44 (2020)102772]
Creators: name: Kox, Jos
name: Bakker, Ellen
name: Zeinstra, SMA Bierma-
name: Runhaar, Jos
name: Miedema, Harald S
name: Roelofs, Pepijn D. D. M.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 399999
subject: Other education not elsewhere classified
classificationCode: 420505
subject: Nursing workforce
classificationCode: 420599
subject: Nursing not elsewhere classified

description: Corrigendum to: “Effective interventions for preventing work related physical health complaints in nursing students and novice nurses: A systematic review” [Nurse Educ. Pract. 44 (2020)102772]
Chemical enrichment in local disc galaxies
Creators: name: Belfiore, Francesco
Publisher: name: Zenodo
Year: 2020

description: Modern integral field spectroscopy surveys are shedding new light onto the chemical enrichment history of discs in the nearby Universe. In this talk I will summarise current results on gas-phase chemical abundances from SDSS-IV MaNGA and MUSE observations of local discs taken by the PHANGS collaboration. With the help of chemical evolution models, I will attempt to draw a coherent picture of chemical enrichment at z=0. Finally, I will discuss some of the challenges of interpreting line emission at kpc scales and recent advances made possible by the higher spatial resolution of PHANGS.
Occurrence of Serious Injury in Real-World Side Impacts of Vehicles with Good Side-Impact Protection Ratings
Creators: name: Brumbelow, Matthew L.
name: Mueller, Becky C.
name: Arbelaez, Raul A.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Physiology
subject: FOS: Biological sciences
subject: Medicine
subject: Biochemistry

description: Objective: The Insurance Institute for Highway Safety (IIHS) introduced its side impact consumer information test program in 2003. Since that time, side airbags and structural improvements have been implemented across the fleet and the proportion of good ratings has increased to 93% of 2012–2014 model year vehicles. Research has shown that drivers of good-rated vehicles are 70% less likely to die in a left-side crash than drivers of poor-rated vehicles. Despite these improvements, side impact fatalities accounted for about one quarter of passenger vehicle occupant fatalities in 2012. This study is a detailed analysis of real-world cases with serious injury resulting from side crashes of vehicles with good ratings in the IIHS side impact test.Methods: NASS-CDS and Crash Injury Research and Engineering Network (CIREN) were queried for occupants of good-rated vehicles who sustained an Abbreviated Injury Scale (AIS) ≥ 3 injury in a side-impact crash. The resulting 110 cases were categorized by impact configuration and other factors that contributed to injury. Patterns of impact configuration, restraint performance, and occupant injury were identified and discussed in the context of potential upgrades to the current IIHS side impact test.Results: Three quarters of the injured occupants were involved in near-side impacts. For these occupants, the most common factors contributing to injury were crash severities greater than the IIHS test, inadequate side-airbag performance, and lack of side-airbag coverage for the injured body region. In the cases where an airbag was present but did not prevent the injury, occupants were often exposed to loading centered farther forward on the vehicle than in the IIHS test. Around 40% of the far-side occupants were injured from contact with the struck-side interior structure, and almost all of these cases were more severe than the IIHS test. The remaining far-side occupants were mostly elderly and sustained injury from the center console, instrument panel, or seat belt. In addition, many far-side occupants were likely out of position due to events preceding the side impact and/or being unbelted.Conclusion: Individual changes to the IIHS side impact test have the potential to reduce the number of serious injuries in real-world crashes. These include impacting the vehicle farther forward (relevant to 28% of all cases studied), greater test severity (17%), the inclusion of far-side occupants (9%), and more restrictive injury criteria (9%). Combinations of these changes could be more effective.
p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency
Creators: name: Prachi N Ghule
name: Xie, Rong-Lin
name: Colby, Jennifer L
name: Jones, Stephen N
name: Lian, Jane B
name: Wijnen, Andre J Van
name: Stein, Janet L
name: Stein, Gary S
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Developmental Biology

description: Histone Nuclear Factor P (HINFP) is essential for expression of histone H4 genes. Ablation of Hinfp and consequential depletion of histones alter nucleosome spacing and cause stalled replication and DNA damage that ultimately result in genomic instability. Faithful replication and packaging of newly replicated DNA are required for normal cell cycle control and proliferation. The tumor suppressor protein p53, the guardian of the genome, controls multiple cell cycle checkpoints and its loss leads to cellular transformation. Here we addressed whether the absence of p53 impacts the outcomes/consequences of Hinfp-mediated histone H4 deficiency. We examined mouse embryonic fibroblasts lacking both Hinfp and p53. Our data revealed that the reduced histone H4 expression caused by depletion of Hinfp persists when p53 is also inactivated. Loss of p53 enhanced the abnormalities in nuclear shape and size (i.e. multi-lobed irregularly shaped nuclei) caused by Hinfp depletion and also altered the sub-nuclear organization of Histone Locus Bodies (HLBs). In addition to the polyploid phenotype resulting from deletion of either p53 or Hinfp, inactivation of both p53 and Hinfp increased mitotic defects and generated chromosomal fragility and susceptibility to DNA damage. Thus, our study conclusively establishes that simultaneous loss of both Hinfp and the p53 checkpoint is detrimental to normal cell growth and may predispose to cellular transformation.
Diffraction catastrophes threaded by quantized vortex skeletons caused by atom-optical aberrations induced in trapped Bose-Einstein condensates
Creators: name: Simula, Tapio
name: Petersen, T. C.
name: Paganin, D. M.
Publisher: name: Swinburne
Year: 2024

description: We propose a nonlinear atom-optics experiment to create diffraction catastrophes threaded by quantized vortex skeletons in Bose-Einstein-condensed matter waves. We show how atom-optical aberrations induced in trapped Bose-Einstein condensates evolve into specific caustic structures due to imperfect focusing. Vortex skeletons, whose cross sections are staggered vortex lattices, are observed to nucleate inside the universal diffraction catastrophes. Our observations shed further light on the structure and dynamics of Bose novae and suggest applications of matter wave diffraction catastrophes, including the detection of the order parameter pairing symmetry in cold gas experiments.
Different views of accountability
Creators: name: Kluvers, Ron
name: Pillay, Somakanthie
Publisher: name: Swinburne
Year: 2024

description: Accountability is a complex and multifaceted concept (Sinclair, 1995) that is made operational through relationships between individuals and organisations (Ebrahim 2003). While accountability may be difficult to define (Ebrahim 2003, Goddard 2005) there is a consensus that it involves a rendering of an account and therefore the provision of information. Underpinning the concept of accountability is the notion that one person is responsible to another, and is obliged to render an account of their decisions and actions to another party. In this study the understanding of accountability held by local government managers and elected councillors will be explored. The research reported in this paper describes how managers and councillors, in Victorian local government, perceive and understand the concept of accountability in a New Public Management (NPM) environment. Results were analysed determine if there were any differences as a result of the location of the council or the position held by the respondent.
Teaching survey evaluations scores and a lecturer's direct control of their performance: an empirical investigation
Creators: name: Foley, Patrick
name: Mitsis, Ann
Publisher: name: Swinburne
Year: 2024

description: Teaching evaluation scores though often organisationally portrayed as an objective measure of teaching quality can also be legitimately seen as a measure of customer service satisfaction that occur within a service context. Within the customer service literature there is range of demographic, cultural and personality trait and service context variables that have been identified as explaining variation in customer service satisfaction ratings. These factors explained variation even when the customer service presentation is identical. This paper examines the possibility that such factors might also apply to teaching evaluations within a University setting. The sample was Business Postgraduate students (n= 548). The study found that 43.4% of the variation in teacher evaluations by student can be accounted for my factors beyond the direct control of the lecturer. Implications of these findings for the growing use of teaching evaluation scores are examined and recommendations for their appropriate use are identified.
Choice at the expense of convention: the new orthodoxy in the sociology of personal life and families
Creators: name: Gilding, Michael
Publisher: name: Swinburne
Year: 2024

description: There is a new orthodoxy in the field that was once understood as the sociology of the family, and is increasingly understood as the sociology of 'personal life' or 'intimacy'. The orthodoxy highlights the open-endedness of intimate relations at the expense of the family as an institution; that is, choice at the expense of convention. It thereby directs attention to the full range of families, relationships, intimacies, sexualities, friendships and acquaintanceships. In doing so, it provides a powerful framework for understanding dramatic shifts in marriage, cohabitation and having children. Yet the orthodoxy comes at a cost. It struggles to conceptualize the institutional foundations of choice. It also routinely overlooks circumstances where some families, relationships, intimacies, sexualities, friendships and acquaintanceships are privileged over others, and prevail over others. This is exemplified in research around paternity uncertainty, inheritance and family business. Not only does the sociology of personal life and families overlook these areas. It concedes them to other disciplines and frameworks, sometimes grounded in biologistic and economistic understandings of human behaviour. The field requires more sophisticated ways of understanding the articulation between choice and convention. This involves renewed consideration of its institutional dimensions, in order to better grasp the enduring weight of convention and the normative dimensions of choice.
A conceptual framework for modelling the antecedents of client loyalty in the advertising industry context
Creators: name: Levin, Elizabeth
name: Lobo, Antonio
Publisher: name: Swinburne
Year: 2024

description: There is no doubt that retention of loyal and committed customers is desirable and profitable in commercial situations. However such relationships are complex and require careful nurturing. This paper develops a model that can be used to determine the key influencers of long term orientation and customer loyalty. In order to contextualise the study, the advertising agency-client relationship has been selected as the focus of the model. A comprehensive conceptual framework is developed which includes variables such as agency offerings incorporating creativity, project management processes and outcome, value, relational bonds, trust, satisfaction, and commitment. All of these are deemed to be important antecedents of loyalty, especially in the business to business context.
Halticoperla McLellan and Winterbourn
Creators: name: McLellan, Ian
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Notonemouridae
Halticoperla

description: Genus Halticoperla McLellan and Winterbourn, 1968 Halticoperla gibbsi McLellan, 1991 Halticoperla tara McLellan, 1991 Halticoperla viridans McLellan and Winterbourn, 1968
description: Published as part of McLellan, Ian, 2006, Endemism And Biogeography Of New Zealand Plecoptera (Insecta), pp. 15-23 in Illiesia 2 (2) on page 23, DOI: 10.5281/zenodo.4754562
Feasibility Study of Airbag Concept Applicable to Motorcycles Without Sufficient Reaction Structure
Creators: name: Aikyo, Yutaka
name: Kobayashi, Yuki
name: Akashi, Tomohiko
name: Ishiwatari, Makoto
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Chemistry
Medicine
Biochemistry

description: Objectives: An airbag system for motorcycle applications was developed and marketed in 2006 followed by many research projects on the system. In the airbag system, the bag should be supported during the kinetic energy–absorbing period of a rider in a collision. The previously developed system employed a configuration in which motorcycle structures support the airbag, such as a gauge unit and/or a steering structure. The supporting structure functions to receive the reaction force to hold the airbag during a crash to properly absorb the rider's kinetic energy. However, the previous system requires a larger area for this reaction structure and is applicable only to the motorcycles that can provide that area. To overcome this limitation, we propose an airbag system employing another concept. In this concept, the airbag does not use its vehicle structures as a reaction structure but uses the structures of an opposing vehicle, such as doors and/or pillars of an opposing vehicle. In this project, we aim to verify the effectiveness of the proposed system when installed in a motorcycle that cannot provide a larger area for the reaction structure.Methods: In the system with this concept, it is assumed that the occupant protection performance is largely affected depending on impact configurations. Accordingly, full-scale motorcycle-to-car crash tests using 125 cm3 scooter-type models with and without the proposed system were conducted in various impact configurations. The 7 impact configurations specified in ISO 13232 were selected as the test configurations. Injury variables and injury indices of head, neck, chest, and abdomen were evaluated with the motorcyclist dummy.Results: Injury variables and indices obtained from the crash tests with the airbag were compared to those of the baseline tests. In 2 impact configurations, the airbags were supported by the side structures of the opposing vehicle and performed to reduce the injury variable of head and/or chest compared to that of the baseline test.Conclusion: Through the crash tests, beneficial protection effects of the airbag system were confirmed in particular impact configurations. No significant risk for the occupant due to the airbag was observed in the conducted crash tests. It was concluded that the proposed airbag system has feasibility to reduce rider injury in a collision of a motorcycle without sufficient reaction structure.
Fast Calculating Surrogate Models for Leg and Head Impact in Vehicle–Pedestrian Collision Simulations
Creators: name: Wimmer, Peter
name: Benedikt, Martin
name: Huber, Philipp
name: Ferenczi, Izabella
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Neuroscience
subject: Cell Biology
subject: Medicine
subject: Biochemistry

description: Objective: In previous research, a tool chain to simulate vehicle–pedestrian accidents from ordinary driving state to in-crash has been developed. This tool chain allows for injury criteria-based, vehicle-specific (geometry, stiffness, active safety systems, etc.) assessments. Due to the complex nature of the included finite element analysis (FEA) models, calculation times are very high. This is a major drawback for using FEA models in large-scale effectiveness assessment studies. Therefore, fast calculating surrogate models to approximate the relevant injury criteria as a function of pedestrian vehicle collision constellations have to be developed.Method: The development of surrogate models for head and leg injury criteria to overcome the problem of long calculation times while preserving high detail level of results for effectiveness analysis is shown in this article. These surrogate models are then used in the tool chain as time-efficient replacements for the FEA model to approximate the injury criteria values. The method consists of the following steps: Selection of suitable training data sets out of a large number of given collision constellations, detailed FEA calculations with the training data sets as input, and training of the surrogate models with the FEA model's input and output values.Results: A separate surrogate model was created for each injury criterion, consisting of a response surface that maps the input parameters (i.e., leg impactor position and velocity) to the output value. In addition, a performance test comparing surrogate model predictions of additional collision constellations to the results of respective FEA calculations was carried out. The developed method allows for prediction of injury criteria based on impact constellation for a given vehicle. Because the surrogate models are specific to a certain vehicle, training has to be redone for a new vehicle. Still, there is a large benefit regarding calculation time when doing large-scale studies.Conclusion: The method can be used in prospective effectiveness assessment studies of new vehicle safety features and takes into account specific local features of a vehicle (geometry, stiffness, etc.) as well as external parameters (location and velocity of pedestrian impact). Furthermore, it can be easily extended to other injury criteria or accident scenarios; for example, cyclist accidents.
The use of 'general principles' as an integrating framework for an entrepreneurship education program
Creators: name: Rushworth, Susan
Publisher: name: Swinburne
Year: 2024

description: This is a theoretical paper with practical intent. It builds on the approach to entrepreneurship education outlined by Fiet (2000a, 2000b). It discusses, in the specific context of entrepreneurship education in Australian universities, the issues and challenges involved in designing an integrated program of study in which units of study build on and complement each other and relate to overall program objectives. It identifies barriers to integrated program design and suggests an approach to help overcome those barriers. Drawing on the literatures of teaching and learning in higher education and of entrepreneurship education, it proposes the use of 'general principles' as an integrating framework simple enough to work within the constraints of the institutional environment.
Austroperla Needham 1905
Creators: name: McLellan, Ian
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Austroperlidae
Austroperla

description: Genus Austroperla Needham, 1905 Austroperla cyrene (Newman) 1845
description: Published as part of McLellan, Ian, 2006, Endemism And Biogeography Of New Zealand Plecoptera (Insecta), pp. 15-23 in Illiesia 2 (2) on page 21, DOI: 10.5281/zenodo.4754562
Features of convection flows and heat transfer in magnetic colloids
Creators: name: Suslov, Sergey
name: Bozhko, Aleksandra
name: Putin, G.
Publisher: name: Swinburne
Year: 2024

description: Undertaken experimental observations and stability analysis have shown that a simple parallel buoyancy-induced flow in a differentially heated vertical layer of ferrofluid that is placed in an external uniform horizontal magnetic field is subject to a number of instabilities leading to the appearance of various convection patterns. Depending on the values of the governing parameters, the instability patterns are found to consist of vertical stationary magneto-convection rolls and/or vertically or obliquely counter-propagating thermo-gravitational or thermo-magnetic waves. Vertical rolls are the most prominent feature of the thermo-magnetic convection while inclined rolls and waves result from the interaction of the magnetic and gravitational mechanisms. Convective flow patterns are characterized by significantly increased heat transfer rates in comparison to pure conduction states. In particular, a significant intensification of an integral heat transfer was observed in convection regimes corresponding to vertical stationary rolls. It is found that these patterns are caused completely by a thermo-magnetic mechanism and are the consequence of an internal magnetic field gradient induced by the temperature dependence of fluid magnetization. These were not detected in earlier experiments and computations.
Measuring stress in entrepreneurs: are existing occupational stress scales relevant?
Creators: name: Grant, Sharon
name: Ferris, Kate
Publisher: name: Swinburne
Year: 2024

description: Although occupational stress has been signalled as an important issue for entrepreneurs, there has been little research on the unique obstacles faced by this group. Much of what we know about occupational stress has come from research on salaried workers with pre-defined jobs in large organisations. The sources of stress that are relevant for salaried workers may be less relevant for self-employed workers. In the current research, entrepreneurs and non-entrepreneurs completed and provided feedback on the relevance of three leading occupational stress scales. Results indicated that many scale items were 'irrelevant' to entrepreneurs. Furthermore, there were several entrepreneurial stressors that were not captured by the scales. The findings confirm the need for a new scale to capture sources of stress that are salient to entrepreneurs.