cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Report of the AACP Task Force on Patient-Centered Medical Homes and Accountable Care Organizations
Creators: name: McGivney, Melissa S.
name: Clark, David R.
name: DeLander, Gary E.
name: Nuffer, Wesley
name: Malloy, Michael
name: Adams, Alex J.
name: Smesny, Andrea L.
name: Mobley, Cary
name: Mackinnon, George E.
name: Parsons, Paige
name: Ives, Timothy J.
name: Smith, Marie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: A task force was convened by the American Association of Colleges of Pharmacy (AACP) to provide rationale for academic pharmacy engagement with organizations/institutions providing new models of team-based patient care designed to improve patient access, care quality, and affordable care. Descriptions of new care models, such as patient centered medical homes (PCMHs) and accountable care organizations (ACO), were included as well as descriptions of existing partnerships with academic pharmacy.
Additional file 1: of Itâ  s more than low BMI: prevalence of cachexia and associated mortality in COPD
Creators: name: Merry-Lynn McDonald
name: Wouters, Emiel
name: Rutten, Erica
name: Casaburi, Richard
name: Rennard, Stephen
name: Lomas, David
name: Bamman, Marcas
name: Bartolome Celli
name: Agusti, Alvar
name: Tal-Singer, Ruth
name: Hersh, Craig
name: Dransfield, Mark
name: Silverman, Edwin
Publisher: name: Figshare
Year: 2019
Subjects: subject: Space Science
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Figure S1. Flow-chart depicting number of participants included in analyses. (PDF 22 kb)
Elevating Research Software: Developing a Roadmap
Creators: name: Jensen, Eric Allen
name: Katz, Daniel S.
Publisher: name: Zenodo
Year: 2023
Subjects: Research software
Research policy
Research systems
DEI
Software sustainability
URSSI
ReSA
Public software
Software maintenance
Software funding
Research funding
Science systems
Career paths
Diversity and inclusion

description: Research software is the unsung hero of modern science. Yet it often plays second fiddle to traditional scholarly outputs such as journal articles. As research grows increasingly computational, the need to recognise software contributions becomes imperative. However, there are a number of challenges that must be overcome to achieve this. How do we measure and extend the impact of research software? How do we integrate it into academic evaluations? A set of answers may be found through policy-related activities, including advocacy, organising, and research. Building on discussions in the US Research Software Sustainability Institute (URSSI), including a number of workshops and an implementation plan that URSSI developed, we've created a set of possible activities aimed at elevating the role of research software in academic career paths, recognition, and beyond. As part of the Alfred P. Sloan-funded URSSI Policy project, we've assembled 44 of these ideas as a starting point, and we've posted them as issues in GitHub. This blog article introduces these ideas and encourages people to contribute.
Der Gewinn der modernen Schriftauslegung für den christlichen Glauben
Creators: name: Deissler, Alfons
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 5 Nr. 5 (1976): Internationale katholische Zeitschrift Communio, Band 5, Heft 5
The LEECH Exoplanet Imaging Survey. Further constraints on the planet architecture of the HR 8799 system
Creators: name: Maire, A. -L.
name: Skemer, A. J.
name: Hinz, P. M.
name: Desidera, S.
name: Esposito, S.
name: Gratton, R.
name: Marzari, F.
name: Skrutskie, M. F.
name: Biller, B. A.
name: Defrère, D.
name: Bailey, V. P.
name: Leisenring, J. M.
name: Apai, D.
name: Bonnefoy, M.
name: Brandner, W.
name: Buenzli, E.
name: Claudi, R. U.
name: Close, L. M.
name: Crepp, J. R.
name: De Rosa, R. J.
name: Eisner, J. A.
name: Fortney, J. J.
name: Henning, T.
name: Hofmann, K. -H.
name: Kopytova, T. G.
name: Males, J. R.
name: Mesa, D.
name: Morzinski, K. M.
name: Oza, A.
name: Patience, J.
name: Pinna, E.
name: Rajan, A.
name: Schertl, D.
name: Schlieder, J. E.
name: Su, K. Y. L.
name: Vaz, A.
name: Ward-Duong, K.
name: Weigelt, G.
name: Woodward, C. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Context. Astrometric monitoring of directly-imaged exoplanets allows the study of their orbital parameters and system architectures. Because most directly-imaged planets have long orbital periods (>20 AU), accurate astrometry is challenging when based on data acquired on timescales of a few years and usually with different instruments. The LMIRCam camera on the LBT is being used for the LEECH survey to search for and characterize young and adolescent exoplanets in L' band, including their system architectures. Aims. We first aim to provide a good astrometric calibration of LMIRCam. Then, we derive new astrometry, test the predictions of the orbital model of 8:4:2:1 mean motion resonance proposed by Goździewski & Migaszewski, and perform new orbital fitting of the HR 8799 bcde planets. We also present deep limits on a putative fifth planet interior to the known planets. Methods. We use observations of HR 8799 and the Theta1 Ori C field obtained during the same run in October 2013. Results. We first characterize the distortion of LMIRCam. We determine a platescale and a true north orientation for the images of 10.707 +/- 0.012 mas/pix and -0.430 +/- 0.076 deg, respectively. The errors on the platescale and true north orientation translate into astrometric accuracies at a separation of 1 of 1.1 mas and 1.3 mas, respectively. The measurements for all planets are usually in agreement within 3 sigma with the ephemeris predicted by Goździewski & Migaszewski. The orbital fitting based on the new astrometric measurements favors an architecture for the planetary system based on 8:4:2:1 mean motion resonance. The detection limits allow us to exclude a fifth planet slightly brighter/more massive than HR 8799 b at the location of the 2:1 resonance with HR 8799 e (~9.5 AU) and about twice as bright as HR 8799 cde at the location of the 3:1 resonance with HR 8799 e (~7.5 AU).
description: 10 pages, 3 figures, accepted for publication in A&A
The Report of the 2012-2013 Research and Graduate Affairs Committee
Creators: name: Schnellmann, Rick G.
name: Cutler, Stephen
name: Derendorf, Hartmut C.
name: Poloyac, Samuel M.
name: Brixner, Diana
name: Lau, Yuen-Sum (Vincent)
name: Ellingrod Ringold, Vicki L.
name: Blouin, Robert
name: Swaan, Peter
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The RGA Committee met on October 29-30, 2012, in Crystal City, VA. The Committee corresponded via e-mail throughout the year, and had a conference call on June 13, 2013. The charge for the RGA Committee was to develop strategies on how to get our members to the right tables and at the right time for advancing pharmacy research and graduate education.
Additional file 3: of Itâ  s more than low BMI: prevalence of cachexia and associated mortality in COPD
Creators: name: Merry-Lynn McDonald
name: Wouters, Emiel
name: Rutten, Erica
name: Casaburi, Richard
name: Rennard, Stephen
name: Lomas, David
name: Bamman, Marcas
name: Bartolome Celli
name: Agusti, Alvar
name: Tal-Singer, Ruth
name: Hersh, Craig
name: Dransfield, Mark
name: Silverman, Edwin
Publisher: name: Figshare
Year: 2019
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Figure S3. Relationship between 1-year change in emphysema with cachexia and weight-loss. (PDF 5 kb)
Additional file 4: of Itâ  s more than low BMI: prevalence of cachexia and associated mortality in COPD
Creators: name: Merry-Lynn McDonald
name: Wouters, Emiel
name: Rutten, Erica
name: Casaburi, Richard
name: Rennard, Stephen
name: Lomas, David
name: Bamman, Marcas
name: Bartolome Celli
name: Agusti, Alvar
name: Tal-Singer, Ruth
name: Hersh, Craig
name: Dransfield, Mark
name: Silverman, Edwin
Publisher: name: Figshare
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Table S1. Characteristics of ECLIPSE Study COPD cases stratified by BMI category. Continuous variables (age, FEV1pp) are represented by median (IQR). * indicates Pâ
A Mentoring Program to Help Junior Faculty Members Achieve Scholarship Success
Creators: name: Kohn, Harold
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The University of North Carolina Eshelman School of Pharmacy launched the Bill and Karen Campbell Faculty Mentoring Program (CMP) in 2006 to support scholarship-intensive junior faculty members. This report describes the origin, expectations, principles, and best practices that led to the introduction of the program, reviews the operational methods chosen for its implementation, provides information about its successes, and analyzes its strengths and limitations.
How Crises Shape Circles of Solidarity: Evidence From the COVID-19 Pandemic in Italy
Creators: name: Hooghe, Liesbet
name: Ferwerda, Jeremy
name: Marks, Gary
name: Magni, Gabriele
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: How has the COVID-19 pandemic affected boundaries of solidarity? Human-induced crises that impose asymmetric costs tend to sharpen pre-existing divides, but natural disasters often strengthen solidarity. The pandemic possesses properties of both kinds of crisis. In a panel survey conducted in Northern Italy, the initial epicenter of the pandemic, we asked respondents to complete conjoint tasks querying who was likely to violate health guidelines (wave 1) and who should be prioritized for vaccine distribution (wave 2). We find that while discrimination towards the rich is nearly universal, bias against other outgroups depends on ideology and personal experience with the crisis. Leftwing individuals display discrimination towards partisan outgroups, while those on the right display ethnic bias. However, this effect is conditional: those who suffered a significant income loss but no health effects display heightened discrimination, while respondents who experienced COVID-19 as a personal health crisis are less likely to penalize outgroups.
Erzieht die Beichtpraxis der Kirche zu politischer Feigheit?
Creators: name: Greiner, Franz
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 5 Nr. 4 (1976): Internationale katholische Zeitschrift Communio, Band 5, Heft 4
title:  Sulla tenerezza
Creators: name: Vigna ,  Carmelo
Publisher: name: Roma TrE-Press
Year: 2014

description: L'articolo è composto da alcune brevi riflessioni sulla tenerezza, sulla sua essenza "femminile", sulla sua naturale presenza nei legami amorosi, sulla necessità di essa nella politica.
description: B@belonline vol. 16/17 Pensare Altrimenti
Fermionic Models with Superconducting Circuits
Creators: name: Heras, U. Las
name: García-Álvarez, L.
name: Mezzacapo, A.
name: Solano, E.
name: Lamata, L.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a method for the efficient quantum simulation of fermionic systems with superconducting circuits. It consists in the suitable use of Jordan-Wigner mapping, Trotter decomposition, and multiqubit gates, be with the use of a quantum bus or direct capacitive couplings. We apply our method to the paradigmatic cases of 1D and 2D Fermi-Hubbard models, involving couplings with nearest and next-nearest neighbours. Furthermore, we propose an optimal architecture for this model and discuss the benchmarking of the simulations in realistic circuit quantum electrodynamics setups.
description: Published in EPJ Quantum Technology
Impact of the COVID-19 pandemic on the quality of medical products in Zimbabwe: a qualitative study based on key informant interviews with health system stakeholders
Creators: name: Yemeke, Tatenda T.
name: Ferrand, Rashida A.
name: Ozawa, Sachiko
name: Umaru, Farouk A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Objective To explore the impact of the Coronavirus disease 2019 (COVID-19) pandemic on the quality of medical products in Zimbabwe, including market risks for substandard and falsified products and impacts on quality assurance activities. Design Qualitative study based on in-depth key informant interviews. Setting Health system stakeholders across the medical product supply chain in Zimbabwe. Participants 36 key informants were interviewed between April and June 2021. Results We found that the COVID-19 pandemic disrupted quality assurance and regulatory activities of medical products in Zimbabwe, resulted in observations of poor-quality personal protective equipment (PPE) and other COVID-19-related products and led to increased risks to quality. Risks to quality due to COVID-19-related disruptions included increased layers of agents in the supply chain and an influx of non-traditional suppliers. COVID-19-related movement restrictions reduced access to health facilities and thus may have increased the usage of the informal market where smuggled and unregistered medical products are sold with less oversight by the regulator. Most reports of poor-quality medical products were for PPE, such as masks and infrared thermometers, used for the COVID-19 response. Besides these reports, many participants stated that the quality of essential medicines in the formal sector, not related to COVID-19, had largely been maintained during the pandemic due to the regulator’s stringent quality assurance process. Incentives for suppliers to maintain quality to retain large donor-funded contracts, and the need for local wholesalers and distributors to comply with quality-related aspects of distribution agreements with global manufacturers of brand-name medical products, mitigated threats to quality. Conclusions The COVID-19 pandemic presented opportunities and market risks for circulation of substandard and falsified medical products in Zimbabwe. There is a need for policymakers to invest in measures to safeguard the quality of medical products during emergencies and to build resiliency against future supply chain shocks.
Additional file 1: of Evaluating the implementation and impact of a pharmacy technician-supported medicines administration service designed to reduce omitted doses in hospitals: a qualitative study
Creators: name: Seston, Elizabeth
name: Ashcroft, Darren
name: Lamerton, Elizabeth
name: Harper, Lindsay
name: Keers, Richard
Publisher: name: Figshare
Year: 2019
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Summary of interview schedule (TECHMED). a summary of topic areas and questions for participants during interviews (DOCX 58 kb)
Association of Health Sciences Reasoning Test Scores With Academic and Experiential Performance
Creators: name: Cox, Wendy C.
name: McLaughlin, Jacqueline E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Objectives. To assess the association of scores on the Health Sciences Reasoning Test (HSRT) with academic and experiential performance in a doctor of pharmacy (PharmD) curriculum.
Evolution of Self-Care Education
Creators: name: Bastianelli, Karen M.S.
name: Ambizas, Emily M.
name: Ferreri, Stefanie P.
name: VanAmburgh, Jenny A.
name: Wilhelm, Miranda
name: Stutz, Misty M.
name: Orr, Katherine Kelly
name: Haines, Seena L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: During the past 15 years, the curriculum content for nonprescription medication and self-care therapeutics has expanded significantly. Self-care courses ranging from stand-alone, required courses to therapeutic content and skills laboratories, have evolved in colleges and schools of pharmacy to accommodate rapid changes related to nonprescription medications and to meet the needs of students. The design of and content delivery methods used in self-care courses vary among institutions. Teaching innovations such as team-based learning, role playing/vignettes, videos, and social media, as well as interdisciplinary learning have enhanced delivery of this content. Given that faculty members train future pharmacists, they should be familiar with the new paradigms of Nonprescription Safe Use Regulatory Expansion (NSURE) Initiative, nonprescription medications for chronic diseases, and the growing trends of health and wellness in advancing patient-care initiatives. This paper reviews the significant changes that may be impacting self-care curriculums in the United States.
title: The ecclesiology of the papacy of Honorius II (1124-1130), with a preliminary calendar of letters
Creators: name: Veneziani, Enrico
Publisher: name: University of St Andrews
Year: 2018

description: This thesis analyses the idea of the Church adopted by the papacy of Honorius II (1124-1130), a pontificate hitherto overlooked by most historians. The main sources, examined with a particular focus on language and context, are the extant letters produced by the papal chancery, which present the official Roman view. A preliminary calendar of the letters is compiled here for the first time and is intended as a tool for future research. Chronicles and other sources are also used to expand the analysis. The first section explores the papacy’s theoretical assertions of primacy over the whole Church and the innovations of the chancery led by Haimeric (1123-1141). It argues that this pontificate added a degree of novelty to ideas already in use (such as the maternal role of the Roman church) but also made new and stronger claims for the papal office. Chapter two considers the consequences of these claims on papal relations with other ecclesiastical institutions and the tools Honorius resorted to when asserting his primacy. It concludes that some of these – especially papal legates – were adapted to the pope’s needs or achieved an even more significant role during this papacy, allowing Honorius to exercise a certain pragmatic primacy over the whole Church. Chapter three deals with relations with secular powers. Although this is afflicted by a serious dearth of letters – the silences of Honorius - the chapter demonstrates that it is still possible to recreate some sense of the modus operandi towards secular powers. It argues that the papacy was usually responsive and its actual power quite limited. The last section offers a case study of Honorius’s relations with Montecassino. Compared with two almost contemporary cases at Cluny and Farfa, this exposes how the ecclesiology of this papacy worked in detail. It argues that these episodes should be read together as a papal attempt to assert primacy over institutions which had always pursued a policy independent from Rome. The image emerging from this analysis frames Honorius’s papacy more effectively, overturning the idea of a transitional and colourless pope. This was a vital pontificate, during which some significant innovations and claims were made. In particular, by adapting the content of each letter to addressee and context, Honorius’s chancery, led by Haimeric, played a decisive role in extending the ecclesiology of the papacy.
Faculty Development Program Models to Advance Teaching and Learning Within Health Science Programs
Creators: name: Lancaster, Jason W.
name: Persky, Adam M.
name: MacLean, Linda Garrelts
name: Van Amburgh, Jenny
name: Stein, Susan M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Within health science programs there has been a call for more faculty development, particularly for teaching and learning. The primary objectives of this review were to describe the current landscape for faculty development programs for teaching and learning and make recommendations for the implementation of new faculty development programs. A thorough search of the pertinent health science databases was conducted, including the Education Resource Information Center (ERIC), MEDLINE, and EMBASE, and faculty development books and relevant information found were reviewed in order to provide recommendations for best practices. Faculty development for teaching and learning comes in a variety of forms, from individuals charged to initiate activities to committees and centers. Faculty development has been effective in improving faculty perceptions on the value of teaching, increasing motivation and enthusiasm for teaching, increasing knowledge and behaviors, and disseminating skills. Several models exist that can be implemented to support faculty teaching development. Institutions need to make informed decisions about which plan could be most successfully implemented in their college or school.
Incorporating lesion-to-lesion heterogeneity into early oncology decision making
Creators: name: Cao, Yanguang
name: Topp, Brian
name: Kumar, Rukmini
name: Qi, Timothy
Publisher: name: Frontiers Media S.A.
Year: 2023

description: RECISTv1.1 (Response Evaluation Criteria In Solid Tumors) is the most commonly used response grading criteria in early oncology trials. In this perspective, we argue that RECISTv1.1 is ambiguous regarding lesion-to-lesion variation that can introduce bias in decision making. We show theoretical examples of how lesion-to-lesion variability causes bias in RECISTv1.1, leading to misclassification of patient response. Next, we review immune checkpoint inhibitor (ICI) clinical trial data and find that lesion-to-lesion heterogeneity is widespread in ICI-treated patients. We illustrate the implications of ignoring lesion-to-lesion heterogeneity in interpreting biomarker data, selecting treatments for patients with progressive disease, and go/no-go decisions in drug development. Further, we propose that Quantitative Systems Pharmacology (QSP) models can aid in developing better metrics of patient response and treatment efficacy by capturing patient responses robustly by considering lesion-to-lesion heterogeneity. Overall, we believe patient response evaluation with an appreciation of lesion-to-lesion heterogeneity can potentially improve decision-making at the early stage of oncology drug development and benefit patient care.
Perceptions of Tenure and Tenure Reform in Academic Pharmacy
Creators: name: Radhakrishnan, Rajan
name: Jordan, Ronald P.
name: Oliveira, Marcos A.
name: Whalen, Karen L.
name: Rhoney, Denise H.
name: Cutler, Stephen J.
name: Pfeiffenberger, Jill A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Objectives. To determine the academic pharmacy community’s perceptions of and recommendations for tenure and tenure reform.
The Giant Molecular Cloud Environments of Infrared Dark Clouds
Creators: name: Hernandez, Audra K.
name: Tan, Jonathan C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We study Giant Molecular Cloud (GMC) environments surrounding 10 Infrared Dark Clouds (IRDCs), using $^{13}$CO(1-0) emission from the Galactic Ring Survey. We measure physical properties of these IRDCs/GMCs on a range of scales extending to radii, R, of 30 pc. By comparing different methods for defining cloud boundaries and for deriving mass surface densities and velocity dispersions, we settle on a preferred "CE,$τ$,G" method of "Connected Extraction" in position-velocity space plus Gaussian fitting to opacity-corrected line profiles for velocity dispersion and mass estimation. We examine how cloud definition affects measurements of the magnitude and direction of line-of-sight velocity gradients and velocity dispersions, including associated dependencies on size scale. CE,$τ$,G-defined GMCs show velocity dispersion versus size relations $σ\propto{s}^{1/2}$, which are consistent with the large-scale gradients being caused by turbulence. However, IRDCs have velocity dispersions that are moderately enhanced above those predicted by this scaling relation. We examine the dynamical state of the clouds finding mean virial parameters $\barα_{\rm{vir}}\simeq 1.0$ for GMCs and 1.6 for IRDCs, broadly consistent with models of magnetized virialized pressure-confined polytropic clouds, but potentially indicating that IRDCs have more disturbed kinematics. CE,$τ$,G-defined clouds exhibit a tight correlation of $σ/R^{1/2}\proptoΣ^n$, with $n\simeq0.7$ for GMCs and 1.3 for IRDCs (c.f., a value of 0.5 expected for a population of virialized clouds). We conclude that while GMCs show evidence for virialization over a range of scales, IRDCs may be moderately super virial. Alternatively, IRDCs could be virialized but have systematically different $^{13}$CO gas phase abundances, i.e., due to freeze-out, affecting mass estimations.
description: 33 pages, 19 figures, Accepted to ApJ
Anerkennung der Confessio Augustana durch die katholische Kirche?, 2
Creators: name: Pfnür, Vinzenz
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 5 Nr. 4 (1976): Internationale katholische Zeitschrift Communio, Band 5, Heft 4
Interactions between Bifidobacterium and Bacteroides and human milk oligosaccharides and their associations with infant cognition
Creators: name: Samuel, Tinu M.
name: Zhu, Hongtu
name: Li, Tengfei
name: Hazlett, Heather C.
name: Cho, Seoyoon
name: Elison, Jed T.
name: Howell, Brittany R.
name: Lin, Weili
name: Sprenger, Norbert
name: Baluyot, Kristine
name: Hauser, Jonas
Publisher: name: Frontiers Media S.A.
Year: 2023

description: While ample research on independent associations between infant cognition and gut microbiota composition and human milk (HM) oligosaccharides (HMOs) has been reported, studies on how the interactions between gut microbiota and HMOs may yield associations with cognitive development in infancy are lacking. We aimed to determine how HMOs and species of Bacteroides and Bifidobacterium genera interact with each other and their associations with cognitive development in typically developing infants. A total of 105 mother-infant dyads were included in this study. The enrolled infants [2.9–12 months old (8.09 ± 2.48)] were at least predominantly breastfed at 4 months old. A total of 170 HM samples from the mothers and fecal samples of the children were collected longitudinally. Using the Mullen Scales of Early Learning to assess cognition and the scores as the outcomes, linear mixed effects models including both the levels of eight HMOs and relative abundance of Bacteroides and Bifidobacterium species as main associations and their interactions were employed with adjusting covariates; infant sex, delivery mode, maternal education, site, and batch effects of HMOs. Additionally, regression models stratifying infants based on the A-tetrasaccharide (A-tetra) status of the HM they received were also employed to determine if the associations depend on the A-tetra status. With Bacteroides species, we observed significant associations with motor functions, while Bif. catenulatum showed a negative association with visual reception in the detectable A-tetra group both as main effect (value of p = 0.012) and in interaction with LNFP-I (value of p = 0.007). Additionally, 3-FL showed a positive association with gross motor (p = 0.027) and visual reception (p = 0.041). Furthermore, significant associations were observed with the interaction terms mainly in the undetectable A-tetra group. Specifically, we observed negative associations for Bifidobacterium species and LNT [breve (p = 0.011) and longum (p = 0.022)], and positive associations for expressive language with 3′-SL and Bif. bifidum (p = 0.01), 6′-SL and B. fragilis (p = 0.019), and LNFP-I and Bif. kashiwanohense (p = 0.048), respectively. Our findings suggest that gut microbiota and HMOs are both independently and interactively associated with early cognitive development. In particular, the diverse interactions between HMOs and Bacteroides and Bifidobacterium species reveal different candidate pathways through which HMOs, Bifidobacterium and Bacteroides species potentially interact to impact cognitive development in infancy.
Rational and Experiential Decision-Making Preferences of Third-Year Student Pharmacists
Creators: name: Cox, Wendy C.
name: McLaughlin, Jacqueline E.
name: Shepherd, Greene
name: Williams, Charlene R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Objective. To examine the rational (systematic and rule-based) and experiential (fast and intuitive) decision-making preferences of student pharmacists, and to compare these preferences to the preferences of other health professionals and student populations.
Spinor Bose gas in an elongated trap
Creators: name: Uchino, Shun
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We examine a spinor Bose gas confined by an elongated trap. Since a spin-independent energy is much higher than a spin-dependent energy in alkali species, the system exhibits different properties by changing a radial confinement. We show that if a spin-dependent coupling is positive, a spin-liquid condensate, which breaks the charge U(1) symmetry but preserves the spin rotational symmetry, can be realized in an intermediate confinement regime. Properties of the spin-liquid condensate are visible if a temperature is lower than a spin gap to characterize the spin-disorder property. If a temperature is higher than the gap but lower than a spin-dependent coupling, on the other hand, a regime in which a spin sector is described by a semiclassical wave emerges. A characterization in each regime by means of correlation functions and topological solitons is also discussed.
description: 6 pages, 1 figure
The structure of current layers and degree of field line braiding in coronal loops
Creators: name: Pontin, D. I.
name: Hornig, G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: One proposed resolution to the long-standing problem of solar coronal heating involves the buildup of magnetic energy in the corona due to turbulent motions at the photosphere that braid the coronal field, and the subsequent release of this energy via magnetic reconnection. In this paper the ideal relaxation of braided magnetic fields modelling solar coronal loops is followed. A sequence of loops with increasing braid complexity is considered, with the aim of understanding how this complexity influences the development of small scales in the magnetic field, and thus the energy available for heating. It is demonstrated that the ideally accessible force-free equilibrium for these braided fields contains current layers of finite thickness. It is further shown that for any such braided field, if a force-free equilibrium exists then it should contain current layers whose thickness is determined by length scales in the field line mapping. The thickness and intensity of the current layers follow scaling laws, and this allows us to extrapolate beyond the numerically accessible parameter regime and to place an upper bound on the braid complexity possible at coronal plasma parameters. At this threshold level the braided loop contains $10^{26}$--$10^{28}{\rm ergs}$ of available free magnetic energy, more than sufficient for a large nanoflare.
description: To appear in ApJ. 20 pages, 10 figures
SLUG -- Stochastically Lighting Up Galaxies. III: A Suite of Tools for Simulated Photometry, Spectroscopy, and Bayesian Inference with Stochastic Stellar Populations
Creators: name: Krumholz, Mark R.
name: Fumagalli, Michele
name: da Silva, Robert L.
name: Rendahl, Theodore
name: Parra, Jonathan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Stellar population synthesis techniques for predicting the observable light emitted by a stellar population have extensive applications in numerous areas of astronomy. However, accurate predictions for small populations of young stars, such as those found in individual star clusters, star-forming dwarf galaxies, and small segments of spiral galaxies, require that the population be treated stochastically. Conversely, accurate deductions of the properties of such objects also requires consideration of stochasticity. Here we describe a comprehensive suite of modular, open-source software tools for tackling these related problems. These include: a greatly-enhanced version of the slug code introduced by da Silva et al. (2012), which computes spectra and photometry for stochastically- or deterministically-sampled stellar populations with nearly-arbitrary star formation histories, clustering properties, and initial mass functions; cloudy_slug, a tool that automatically couples slug-computed spectra with the cloudy radiative transfer code in order to predict stochastic nebular emission; bayesphot, a general-purpose tool for performing Bayesian inference on the physical properties of stellar systems based on unresolved photometry; and cluster_slug and sfr_slug, a pair of tools that use bayesphot on a library of slug models to compute the mass, age, and extinction of mono-age star clusters, and the star formation rate of galaxies, respectively. The latter two tools make use of an extensive library of pre-computed stellar population models, which are included the software. The complete package is available at http://www.slugsps.com.
description: 24 pages, 13 figures, accepted for publication in MNRAS; some additions to previous version; source code and model libraries are available at http://www.slugsps.com
Tinnitus and the arts workshop report
Creators: name: Thompson, Marie
Publisher: name: The Open University
Year: 2022
Subjects: Other creative arts and writing not elsewhere classified

description: In 2021, Marie Thompson (The Open University), Patrick Farmer (Oxford Brookes University) and Sally Blackburn-Daniels (The Open University) ran a series of online workshops exploring how art activities might be used to share different experiences of tinnitus. The purpose of the workshops was to explore the following questions: Can art activities be used by people with tinnitus to share their experiences? Can art activities enrich understandings of tinnitus, and the diverse ways it affects listeners? How might engaging in art activities about tinnitus be beneficial to members of the tinnitus community? Participants were given instructions for six art activities and asked to complete at least two. The activities allowed participants to use a range of creative methods, including drawing, map-making, creative writing, and sound recording. No previous experience was needed to take part. Participants were asked to share their responses with the project team, as well as any thoughts they had about the activities. The six activities were: Tinnitus maps: creating a map of where tinnitus is louder or quieter, or more or less noticeable Tinnitus portraits: developing a self-portrait that includes tinnitus, showing where the sound travels from and to Tinnitus drawing: exploring how tinnitus might be depicted without words by making a series of drawings Putting tinnitus into words: a creative writing exercise, where each person chooses a word or set of words that they associate with tinnitus and provides a definition for them Keeping score: turning tinnitus into a ‘word-sound’ that is then used to create a visual score or sound recording Capturing sounds: finding, making and documenting sounds that relate to each person’s tinnitus in some way This is a report for participants that took part in the Tinnitus and the Arts workshops, providing details of who took part, participant responses to the activities, and possible future avenues for development.
An Exploratory Analysis of Personality, Attitudes, and Study Skills on the Learning Curve within a Team-based Learning Environment
Creators: name: Henry, Teague
name: Persky, Adam M.
name: Campbell, Ashley
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Objective. To examine factors that determine the interindividual variability of learning within a team-based learning environment.
Development and Assessment of the Multiple Mini-Interview in a School of Pharmacy Admissions Model
Creators: name: Dinkins, Melissa M.
name: Cox, Wendy C.
name: McLaughlin, Jacqueline E.
name: Lewis, Margaret
name: Singer, David
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Objective. To describe the development, implementation, and evaluation of the multiple mini-interview (MMI) within a doctor of pharmacy (PharmD) admissions model.
Wie unterscheiden sich christliches und Marxsches Menschenbild?
Creators: name: Messner, Johannes
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 5 Nr. 4 (1976): Internationale katholische Zeitschrift Communio, Band 5, Heft 4
Early Clinical Experiences for Second-Year Student Pharmacists at an Academic Medical Center
Creators: name: Rodgers, Philip T.
name: Arnall, Justin
name: Roth, Mary T.
name: Chen, Sheh-Li
name: Amerine, Lindsey B.
name: Pinelli, Nicole R.
name: Williams, Dennis M.
name: McLaughlin, Jacqueline E.
name: Luter, David N.
name: Smith, Shayna
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Objective. To examine student outcomes associated with the Student Medication and Reconciliation Team (SMART) program, which was designed to provide second-year student pharmacists at the University of North Carolina (UNC) Eshelman School of Pharmacy direct patient care experience at UNC Medical Center.
Additional file 5: of Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models
Creators: name: Sabol, Rachel
name: Bowles, Annie
name: Côté, Alex
name: Wise, Rachel
name: Benjamen O’Donnell
name: Matossian, Margarite
name: Fokhrul Hossain
name: Burks, Hope
name: Valle, Luis
name: Miele, Lucio
name: Collins-Burow, Bridgette
name: Burow, Matthew
name: Bunnell, Bruce
Publisher: name: Figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer

description: Figure S5. shRNA knockdown of leptin in obASCs. (A) Representative images of metastases are shown and were acquired at identical magnification (scale bar = 100 μm). (B) Leptin expression in control shRNA obASCs versus leptin shRNA obASCs was compared to evaluate knockdown efficiency. Leptin knockdown was confirmed via Western blot. Values reported are the mean of three independent experiments each performed in triplicate. Bars, ± SEM. *p
Incoherent Pion Production in Neutrino - Deuteron Reactions
Creators: name: Wu, Jia-Jun
name: Sato, T.
name: Lee, T. -S. H.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Within the multiple scattering formulation, the incoherent pion production in neutrino-deuteron reactions at energies near the $Δ(1232)$ resonance is investigated. The calculations include an impulse term and one-loop contributions from nucleon-nucleon ($NN$) and pion-nucleon ($πN$) final state interactions. The input amplitudes of $πN$ scattering and electroweak pion production reaction on nucleon are generated from a dynamical model which describes very extensive data of $πN$ scattering and both the electromagnetic and the weak pion production reactions on the nucleon. The $NN$ scattering amplitudes are generated from the Bonn potential. The validity of the calculational procedures is established by giving a reasonably good description of the data of pion photo-production on the deuteron. The constructed model is then applied to predict the cross sections of $ν+ d \rightarrow μ^- + π^+ + n+ p$ and $ν+d \rightarrow μ^-+π^0+p+p$ reactions. The importance of including the $NN$ final state interactions to understand the experimental data of these neutrino-deuteron reactions is demonstrated. Our results strongly suggest that the spectator approximation used in the previous analyses to extract the pion production cross sections on the nucleon from the data on the deuteron is not valid for the $ν+ d \rightarrow μ^-+ π^+ +n+p$, but is a good approximation for $ν+ d \rightarrow μ^-+ π^0 + p+p$.
description: 22 pages, 13 figures
Limited Predictive Utility of Admissions Scores and Objective Structured Clinical Examinations for APPE Performance
Creators: name: Rodgers, Philip T.
name: Khanova, Julia
name: McLaughlin, Jacqueline E.
name: Cox, Wendy C.
name: Scolaro, Kelly
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Objective. To examine the relationship between admissions, objective structured clinical examination (OSCE), and advanced pharmacy practice experience (APPE) scores.
Involvement of extracellular vesicles in the progression, diagnosis, treatment, and prevention of whole-body ionizing radiation-induced immune dysfunction
Creators: name: Herring, Laura E.
name: Maile, Robert
name: Coleman, Leon G.
name: Willis, Micah L.
name: Wallet, Shannon M.
name: Seim, Roland F.
name: Mordant, Angie L.
Publisher: name: Frontiers Media S.A.
Year: 2023

description: Acute radiation syndrome (ARS) develops after exposure to high doses of ionizing radiation and features immune suppression and organ failure. Currently, there are no diagnostics to identify the occurrence or severity of exposure and there are limited treatments and preventative strategies to mitigate ARS. Extracellular vesicles (EVs) are mediators of intercellular communication that contribute to immune dysfunction across many diseases. We investigated if EV cargo can identify whole body irradiation (WBIR) exposure and if EVs promote ARS immune dysfunction. We hypothesized that beneficial EVs derived from mesenchymal stem cells (MSC-EVs) would blunt ARS immune dysfunction and might serve as prophylactic radioprotectants. Mice received WBIR (2 or 9 Gy) with assessment of EVs at 3 and 7 days after exposure. LC-MS/MS proteomic analysis of WBIR-EVs found dose-related changes as well as candidate proteins that were increased with both doses and timepoints (34 total) such as Thromboxane-A Synthase and lymphocyte cytosolic protein 2. Suprabasin and Sarcalumenin were increased only after 9 Gy suggesting these proteins may indicate high dose/lethal exposure. Analysis of EV miRNAs identified miR-376 and miR-136, which were increased up to 200- and 60-fold respectively by both doses of WBIR and select miRNAs such as miR-1839 and miR-664 were increased only with 9 Gy. WBIR-EVs (9 Gy) were biologically active and blunted immune responses to LPS in RAW264.7 macrophages, inhibiting canonical signaling pathways associated with wound healing and phagosome formation. When given 3 days after exposure, MSC-EVs slightly modified immune gene expression changes in the spleens of mice in response to WBIR and in a combined radiation plus burn injury exposure (RCI). MSC-EVs normalized the expression of certain key immune genes such as NFκBia and Cxcr4 (WBIR), Map4k1, Ccr9 and Cxcl12 (RCI) and lowered plasma TNFα cytokine levels after RCI. When given prophylactically (24 and 3 hours before exposure), MSC-EVs prolonged survival to the 9 Gy lethal exposure. Thus, EVs are important participants in ARS. EV cargo might be used to diagnose WBIR exposure, and MSC-EVs might serve as radioprotectants to blunt the impact of toxic radiation exposure.
Student Perceptions of a Flipped Pharmacotherapy Course
Creators: name: Roth, Mary T.
name: Rhoney, Denise H.
name: McLaughlin, Jacqueline E.
name: Harris, Suzanne
name: Khanova, Julia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Objective. To evaluate student perception of the flipped classroom redesign of a required pharmacotherapy course.
tinnitus and the arts workshop report
Creators: name: Thompson, Marie
Publisher: name: The Open University
Year: 2022
Subjects: Other creative arts and writing not elsewhere classified

description: In 2021, Marie Thompson (The Open University), Patrick Farmer (Oxford Brookes University) and Sally Blackburn-Daniels (The Open University) ran a series of online workshops exploring how art activities might be used to share different experiences of tinnitus. The purpose of the workshops was to explore the following questions: Can art activities be used by people with tinnitus to share their experiences? Can art activities enrich understandings of tinnitus, and the diverse ways it affects listeners? How might engaging in art activities about tinnitus be beneficial to members of the tinnitus community? Participants were given instructions for six art activities and asked to complete at least two. The activities allowed participants to use a range of creative methods, including drawing, map-making, creative writing, and sound recording. No previous experience was needed to take part. Participants were asked to share their responses with the project team, as well as any thoughts they had about the activities. The six activities were: Tinnitus maps: creating a map of where tinnitus is louder or quieter, or more or less noticeable Tinnitus portraits: developing a self-portrait that includes tinnitus, showing where the sound travels from and to Tinnitus drawing: exploring how tinnitus might be depicted without words by making a series of drawings Putting tinnitus into words: a creative writing exercise, where each person chooses a word or set of words that they associate with tinnitus and provides a definition for them Keeping score: turning tinnitus into a ‘word-sound’ that is then used to create a visual score or sound recording Capturing sounds: finding, making and documenting sounds that relate to each person’s tinnitus in some way This is a report for participants that took part in the Tinnitus and the Arts workshops, providing details of who took part, participant responses to the activities, and possible future avenues for development.