cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response
Creators: name: Varia, Mahesh A
name: Raleigh, James A
Publisher: name: BioMed Central Ltd
Year: 2011

description: Abstract Introduction Hypoxia in solid tumors is associated with treatment resistance, resulting in poor prognosis. Tribbles homolog 3 (TRIB3) is induced during hypoxia and is involved in multiple cellular pathways involved in cell survival. Here, we investigated the role of TRIB3 in breast cancer. Methods TRIB3 mRNA expression was measured in breast tumor tissue from 247 patients and correlated with clinicopathological parameters and clinical outcome. Furthermore, we studied TRIB3 expression regulation in cell lines, xenografts tissues and human breast cancer material using Reverse transcriptase, quantitative polymerase chain reaction (RT-qPCR) and immunohistochemical staining. Finally, the effect of small interfering RNA (siRNA) mediated TRIB3 knockdown on hypoxia tolerance was assessed. Results Breast cancer patients with low, intermediate or high TRIB3 expression exhibited a mean disease free survival (DFS) of 80 (95% confidence interval [CI] = 74 to 86), 74 (CI = 67 to 81), and 63 (CI = 55 to 71) months respectively (P = .002, Mantel-Cox log-rank). The prognostic value of TRIB3 was limited to those patients that had received radiotherapy as part of their primary treatment (n = 179, P = .005) and remained statistically significant after correction for other clinicopathological parameters (DFS, Hazard Ratio = 1.90, CI = 1.17 to 3.08, P = .009). In breast cell lines TRIB3 expression was induced by hypoxia, nutrient starvation, and endoplasmic reticulum stress in an hypoxia inducible factor 1 (HIF-1) independent manner. TRIB3 induction after hypoxia did not increase with decreasing oxygen levels. In breast tumor xenografts and human breast cancer tissues TRIB3 co-localized with the hypoxic cell marker pimonidazole. The induction of TRIB3 by hypoxia was shown to be regulated via the PERK/ATF4/CHOP pathway of the unfolded protein response and knockdown of TRIB3 resulted in a dose-dependent increase in hypoxia sensitivity. Conclusions TRIB3 is independently associated with poor prognosis of breast cancer patients, possibly through its association with tumor cell hypoxia.
Technological energy and environmental refurbishment of historical Italian libraries
Creators: name: Battisti, Alessandra
name: Tucci, Fabrizio
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2014

description: Active libraries in Italy are around 13.000 and, taken as a whole, the property and management relate mainly to public institutions such as the state, regions, local authorities, cultural institutions, universities, and partly to religious institutions and individuals. In this paper is presented the work of studies and research, commissioned to the authors by the General Direction for Libraries of the Ministry of Heritage and Culture (Mibac), which ended recently, addressing the architectural, energy and environmental refurbishment of national historic libraries distributed on the Italian territory, with special focus on 4 among 46 owned by the Ministry of Culture (the Nazionale Centrale di Roma, the Nazionale Centrale in Florence, the national University of Turin and the Angelica in Rome) believed by the authors and client as examples of recurring issues and ideals to lend itself to the construction of a model of intervention replicable on other historical Italian libraries.The main objective of the project is the identification of physical and perceptual factors of wear2, which threaten the conservation of the historical and artistic heritage of the historic center of Venice, with a particular focus on the effects of anthropogenic pressure linked to tourism, and the evaluation of their level of danger. A further objective is the recognition of measurable parameters (indicators) for monitoring and, subsequently, mitigation strategies for the most significant phenomena.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 8 (2014): Research and project knowledge transfer
Environmental and Social Life Cycle Assessment of welding technologies
Creators: name: Chang, Ya-Ju
name: Sproesser, Gunther
name: Neugebauer, Sabrina
name: Wolf, Kirana
name: Scheumann, René
name: Pittner, Andreas
name: Rethmeier, Michael
name: Finkbeiner, Matthias
Publisher: name: Technische Universität Berlin
Year: 2015
Subjects: subject: 600 Technik, Technologie
subject: fair salary
subject: human health
subject: Life Cycle Assessment
subject: LCA
subject: Social Life Cycle Assessment
subject: SLCA
subject: welding

description: Life Cycle Assessment (LCA) and Social Life Cycle Assessment (SLCA) are applied in evaluating possible social and environmental impacts of the state-of-art welding technologies, such as Manual Metal Arc Welding (MMAW), Manual Gas Metal Arc Welding (GMAW), Automatic GMAW and Automatic Laser-Arc Hybrid Welding (LAHW). The LCA results indicate that for 1 meter weld seam, MMAW consumes the largest amount of resources (like filler material and coating on electrodes) and energy, which contributes to comparatively higher environmental impacts in global warming potential, acidification, photochemical ozone creation potential and eutrophication than other chosen processes. With regard to social aspects, the health issues and fair salary are under survey to compare the relative potential risk on human health caused by fumes in different welding technologies, and to indicate the sufficiency of current salary of welders in Germany. The results reflect that the wage status of welders is still fair and sufficient. The manual processes bring much higher potential risk of welders’ health than the automatic processes, especially MMAW.
Study 4: Modeling social actions in relationships as recursive inference
Creators: name: Hung, Michelle
name: Thomas, Ashley
name: Radkani, Setayesh
name: Tenenbaum, Joshua
name: Saxe, Rebecca
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: In this project, we explore the idea that people view food sharing actions as “bids” to reveal the type and closeness of a relationship. We use a modified Rational Speech Act framework to model the recursive inferences that food sharing interactions allow.
A statistical analysis of the accuracy of the digitized magnitudes of photometric plates on the time scale of decades with an application to the century-long light curve of KIC 8462852
Creators: name: Hippke, Michael
name: Angerhausen, Daniel
name: Lund, Michael B.
name: Pepper, Joshua
name: Stassun, Keivan G.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a statistical analysis of the accuracy of the digitized magnitudes of photometric plates on the time scale of decades. In our examination of archival Johnson B photometry from the Harvard DASCH archive, we find a median RMS scatter of lightcurves of order 0.15mag over the range B~9-17 for all calibrations. Slight underlying systematics (trends or flux discontinuities) are on a level of ~<=0.2mag per century (1889-1990) for the majority of constant stars. These historic data can be unambiguously used for processes that happen on scales of magnitudes, and need to be carefully examined in cases approaching the noise floor. The characterization of these limits in photometric stability may guide future studies in their use of plate archives. We explain these limitations for the example case of KIC8462852, which has been claimed to dim by 0.16mag per century, and show that this trend cannot be considered as significant.
description: ApJ accepted
Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells
Creators: name: Stouffer, George A
Publisher: name: BioMed Central Ltd
Year: 2008

description: Abstract Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand binding to αvβ3 integrins on vascular cells. αvβ3 integrins influence responses to insulin in various cell types but effects in human aortic smooth muscle cells (HASMC) are unknown. Results and discussion Insulin elicited a dose-dependent proliferative response in HASMC. Pretreatment with m7E3 (an anti-β3 integrin monoclonal antibody from which abciximab is derived), c7E3 or LM609 inhibited proliferative responses to insulin by 81%, 59% and 28%, respectively. Eptifibatide or cyclic RGD peptides completely abolished insulin-induced proliferation whereas tirofiban, which binds αIIbβ3 but not αvβ3, had no effect. Insulin-induced increases in c-Jun NH2-terminal kinase-1 (JNK1) activity were partially inhibited by m7E3 and eptifibatide whereas antagonism of αvβ3 integrins had no effect on insulin-induced increases in extracellular signal-regulated kinase (ERK) activity. Insulin stimulated a rapid increase in the number of vinculin-containing focal adhesions per cell and treatment with m7E3, c7E3 or eptifibatide inhibited insulin-induced increases in focal adhesions by 100%, 74% and 73%, respectively. Conclusion These results demonstrate that αvβ3 antagonists inhibit signaling, focal adhesion formation and proliferation of insulin-treated HASMC.
Tactics and Strategy for the SEAP - Action Plan for Sustainable Energy. The city of Alessandria as a case study
Creators: name: Savio, Lorenzo
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2014

description: The European Union has included, since 2007, in its Plan for Energy Efficiency, a specific action addressed to the Cities: the Covenant of Mayors. The initiative involves directly the Mayors, who, signing a document of adhesion, will commit to go beyond the EU target of CO2 reduction, implementing a SEAP: Strategic Energy Action Plan. The SEAP is an innovative planning tool, which allows the city to build an overall scenario for reducing CO2 emissions, with actions belonging to different sectors. In all the steps following the signing of the Covenant (adoption, monitoring, updating the SEAP) it is crucial, for the city, to adopt an effective coordination, able to put a system not only the social actors with key roles, but also all the past experiences, the best practices, demonstration projects and everything which, in the local context, can be con- sidered strategic for a sustainable urban regeneration. In Italy, the Covenant had a considerable success, with more than 1,800 cities, the 55% of the total in Europe. The city of Alessandria can be considered an interesting case study, because the SEAP development was integrated to the European Demonstrative Project Concerto AL Piano, aimed at the regeneration of a urban district, making it sustainable from the energy consumption point of view. The research group of Politecnico di Torino supported Alessandria in all the process.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 8 (2014): Research and project knowledge transfer
Risk security and soil loss mitigation: the EU case study of the Sufalnet Project
Creators: name: Rigillo, Marina
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2014

description: Former and abandoned landfills represent a good opportunity for producing new impervious surfaces for the urban environment, contrasting soil loss (specially the agricultural one) and improving the recovery of brownfield. From such perspective, landfill redevelopment could be intended as the beginning of a new life cycle for the site, corresponding to a kick off action for achieving environmental and socio-economic development. This is the purpose of the Sufalnet Project (Sustainable Use of Former and Abandoned Landfill) that defines a new approach for landfill redevelopment in form of model strategy by which reducing both the risk of the project failure and of the environmental pollution. Model strategy acts as cultural device for managing redevelop- ment process and its complexity.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 8 (2014): Research and project knowledge transfer
Supplementary Figures S1-S4 Garcia et. al. Delayed metabolic disturbances in the myocardium after exertional heat stroke: contrasting effects of exertion and thermal load
Creators: name: Clanton, Thomas
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 319999
subject: Other biological sciences not elsewhere classified

description: These files are supplementary material for a submitted manuscript.Epidemiological studies report higher risks of cardiovascular disease in humans exposed to heat stroke earlier in life. Previously, we explored mechanistic links between heat stroke and developing cardiac abnormalities using a preclinical mouse model of exertional heat stroke (EHS). Profound metabolic abnormalities developed in the ventricles of females after two weeks that were not seen in males. Here we tested whether this lack of response could be attributed to lower exercise performances or reduced thermal loads exhibited by males. We systematically altered environmental temperature (Te) during EHS to manipulate heat exposure and to allow for greater exercise intensity in the males. Three groups of adult C57BL/6 male mice were studied: ‘EHS-34’ (Te = 34°C), ‘EHS-41’ (Te = 41°C), and EHS-39.5 (Te = 39.5°C). Mice ran until symptom limitation (unconsciousness) at max core temperature (Tc,max). After a 2-wk recovery, the mice were euthanized and the ventricles removed for untargeted metabolomics. Results were compared against age-matched non-exercise controls. The EHS-34 mice greatly elevated their exercise performance, but reached lower Tc,max and lower thermal loads. The EHS-41 mice exhibited equivalent thermal loads, exercise times and Tc,max compared to EHS-39.5.The ventricles from EHS-34 mice exhibited the greatest metabolic disturbances, characterized by shifts toward glucose metabolism, reductions in acylcarnitines, increased amino acid metabolites, elevations in antioxidants, altered TCA cycle flux and increased xenobiotics. In conclusion, delayed metabolic disturbances following EHS in male myocardium appear to be greatly amplified by higher levels of exertion in the heat, even with lower thermal loads and max core temperatures.
title: European Jurisdiction on Refugee and Complementary Protection
Creators: name: Hoffmann, Holger
Publisher: name: Quarterly on Refugee Problems - AWR Bulletin
Year: 2022
Subjects: European Court of Human Rights
European Court of Justice
ECtHR
ECJ
Jurisdiction
Case Law
2022
European
Refugee Protection
Complementary Protection

description: This compilation of case law samples, summarizes and refers to jurisdiction of international relevance for the application of legal standards in the field of refugee and complementary protection by the European Court of Human Rights (ECtHR) and the European Court of Justice (ECJ) in the period January to July 2022.
description: Quarterly on Refugee Problems - AWR Bulletin, Vol. 61 No. 1 (2022): Quarterly on Refugee Problems - AWR Bulletin (QRP)
Circular processes for a new urban metabolysm: the role of municipal solid waste in the sustainable requalification
Creators: name: Mamì, Antonella
Publisher: name: TECHNE - Journal of Technology for Architecture and Environment
Year: 2014

description: Through this paper we present the first results of a research combining the management problem of Municipal Solid Waste to the requalification of built environment. The goal of this research is to mitigate the vulnerability of territory and urban heritage and to transform a problem into opportunities. Above all, we have paid attention to several exemplifying cases of Italian territory: suburbs of large towns, historical centres, small centres (and, in particular, those with a strong historical connotation). Their features are, at the same time, restrictions and challenges for designing new compatible systems that can contribute to the requalification of urban landscape recovering spaces with demolition products and residual materials and comparing with managerial needs.
description: TECHNE - Journal of Technology for Architecture and Environment, TECHNE 8 (2014): Research and project knowledge transfer
Sustainable corporate development measured by intangible and tangible resources as well as targeted by safeguard subjects
Creators: name: Orth, Ronald
name: Scheumann, René
name: Galeitzke, Mila
name: Wolf, Kirana
name: Kohl, Holger
name: Finkbeiner, Matthias
Publisher: name: Technische Universität Berlin
Year: 2015
Subjects: subject: 600 Technik, Technologie
subject: sustainability
subject: corporate development
subject: Life Cycle Sustainability Assessment
subject: LCSA
subject: safeguard subjects
subject: capital approach

description: The needed shift towards sustainable development in existing business processes can be achieved through the combination of the capital based approach and the life cycle sustainability assessment. This contribution performs an analysis and selection of assessment tools and indicators regarding the resources used in organisational processes and the life cycle of the products or services to measure the potential impacts on the environment and society. The relevance of intangible capital to improve the organisational sustainability performance as well as the expansion of the traditional dimensions of sustainability with the target of the six safeguard subjects: human health, social justice, ecosystem quality, financial stability, resource availability and man-made environment are integrated into a conceptual framework. This approach allows the development and implementation of strategies towards sustainable corporate development through a recommendation-based framework.
NPHS2 variation in focal and segmental glomerulosclerosis
Creators: name: Falk, Ronald J.
Publisher: name: BioMed Central Ltd
Year: 2008

description: Abstract Background Focal and segmental glomerulosclerosis (FSGS) is the most common histologic pattern of renal injury seen in adults with idiopathic proteinuria. Homozygous or compound heterozygous mutations in the podocin gene NPHS2 are found in 10–30% of pediatric cases of steroid resistant nephrosis and/or FSGS. Methods We studied the spectrum of genetic variation in 371 individuals with predominantly late onset FSGS (mean age of onset 25 years) by analysis of DNA samples. Results We identified 15 non-synonymous alleles that changed the amino acid sequence in 63 of the subjects screened (17%). Eight of these (p.R138Q, p.V180M, p.R229Q, p.E237Q, p.A242V, p.A284V, p.L327F and the frameshift 855–856 delAA) are alleles previously reported to cause FSGS in either the homozygous or compound heterozygous states, while the remaining 7 (p.R10T, p.V127W, p.Q215X, p.T232I, p.L270F, p.L312V and the frameshift 397delA) are novel alleles that have not been demonstrated previously. Twelve individuals of the 371 (3.2%) screened had two likely disease-causing NPHS2 alleles, present in either a homozygous or compound heterozygous state. We genotyped the two most common of the non-synonymous NPHS2 alleles (p.A242V and p.R229Q) identified by resequencing in participants from the Nurses' Health Study and also genotyped p.R229Q in 3 diabetic cohorts. We found that the presence of either of these variants does not significantly alter the risk of albuminuria in the Nurses' Health participants, nor does p.R229Q associate with "diabetic nephropathy". Conclusion NPHS2 mutations are a rare cause of FSGS in adults. The most common non-synonymous NPHS2 variants, p.R229Q and p.A242V, do not appear to alter the risk of proteinuria in the general population nor does p.R229Q associate with measures of kidney dysfunction in diabetic individuals. Our results help clarify the frequency of FSGS-causing NPHS2 mutations in adults and broaden our understanding of the spectrum of NPHS2 mutations that lead to human disease.
Photon emission in neutral current interactions at the T2K experiment
Creators: name: Wang, E.
name: Alvarez-Ruso, L.
name: Hayato, Y.
name: Mahn, K.
name: Nieves, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We have applied a microscopic model for single photon emission in neutral current interactions on nucleons and nuclei to determine the number and distributions of such events at the Super-Kamiokande detector, for the flux and beam exposure of the T2K experiment in neutrino mode. These reactions represent an irreducible background in electron-(anti)neutrino appearance measurements aimed at a precise measurement of mixing angle $θ_{13}$ and the $CP$ violating phase. We have obtained a total number of photon events that is twice larger than the one from the NEUT event generator (version 5.1.4.2) used in the analysis of T2K data. Detailed comparisons of energy and angular distributions for the $ν_μ$ and $\barν_μ$ fluxes have also been performed.
description: 9 pages, 6 figures
Spiral waves triggered by shadows in transition disks
Creators: name: Montesinos, Matias
name: Perez, Sebastian
name: Casassus, Simon
name: Marino, Sebastian
name: Cuadra, Jorge
name: Christiaens, Valentin
Publisher: name: arXiv
Year: 2016
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Circumstellar asymmetries such as central warps have recently been shown to cast shadows on outer disks. We investigate the hydrodynamical consequences of such variable illumination on the outer regions of a transition disk, and the development of spiral arms. Using 2D simulations, we follow the evolution of a gaseous disk passively heated by the central star, under the periodic forcing of shadows with an opening angle of $\sim$28$^\circ$. With a lower pressure under the shadows, each crossing results in a variable azimuthal acceleration, which in time develops into spiral density waves. Their pitch angles evolve from $Π\sim 15^\circ-22^\circ$ at the onset, to $\sim$11$^\circ$-14$^\circ$, over $\sim$65~AU to 150~AU. Self-gravity enhances the density contrast of the spiral waves, as also reported previously for spirals launched by planets. Our control simulations with unshadowed irradiation do not develop structures, except for a different form of spiral waves seen at later times only in the gravitationally unstable control case. Scattered light predictions in the $H$-band show that such illumination spirals should be observable. We suggest that spiral arms in the case-study transition disk HD~142527 could be explained as a result of shadowing from the tilted inner disk.
description: 6 pages, 4 figures, 1 table. Accepted for publication in ApJL
A nationwide observational study in heavily pretreated metastatic HER2-positive breast cancer patients
Creators: name: Due, Asbjørn
name: Berg, Tobias
name: Jensen, Maj-Britt
name: Yammeni, Sophie
name: Volmer, Lone
name: Brems-Eskildsen, Anne Sofie
name: Andersen, Klaus Kaae
name: Rana, Saeeda
name: Knoop, Ann
name: Kümler, Iben
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: FOS: Biological sciences

description: Current guidelines in HER2-positive metastatic breast cancer (mBC) recommend the combination of trastuzumab and a chemotherapeutic agent for 3rd line or later treatments. This study aims to describe the treatment of HER2-positive mBC in 3rd line or later after previous treatment with T-DM1 for mBC in a real-world setting. This observational population-based study included all women diagnosed with HER2-positive mBC in Denmark, previously treated with T-DM1 in the metastatic setting. Patients were included on the date of progression leading to initiation of 3rd line treatment if the patient had received T-DM1 in 1st or 2nd line. If the patient received T-DM1 in 3rd line or later the inclusion was based on the date of progression on T-DM1. The primary end points were overall survival (OS) and progression-free survival (PFS). The study included 272 women with a mean age of 59 (27–86) and a median of 3 (2–11) treatment lines prior to inclusion. At index, all patients had received T-DM1 and 167 (62%) patients had received pertuzumab in the metastatic setting. During follow-up 183 patients received chemotherapy. Of these patients, 120 received chemotherapy combined with trastuzumab, 50 received chemotherapy combined with other HER2-targeted therapy, and 13 received chemotherapy as monotherapy. The remaining 89 patients received either HER2-targeted monotherapy (41), endocrine therapy (31), experimental treatment (10), or no treatment (7). Median PFS was 5.5 months (95% CI, 4.8–6.5) and median OS was 18.5 months (95% CI, 16.2–21.3). In this real-world study, we found that patients were treated with a wide variety of anti-cancer agents with modest efficacy. However, patients in this study did not have access to newer therapies like tucatinib and T-DXd.
Development of a proxy-reported pulmonary outcome scale for preterm infants with bronchopulmonary dysplasia
Creators: name: Tolleson-Rinehart, Sue
name: Powell, Leslie M
name: DeWalt, Darren A
name: Massie, Sara E
name: Laughon, Matthew
name: Price, Wayne A
Publisher: name: BioMed Central Ltd
Year: 2011

description: Abstract Background To develop an accurate, proxy-reported bedside measurement tool for assessment of the severity of bronchopulmonary dysplasia (also called chronic lung disease) in preterm infants to supplement providers' current biometric measurements of the disease. Methods We adapted Patient-Reported Outcomes Measurement Information System (PROMIS) methodology to develop the Proxy-Reported Pulmonary Outcomes Scale (PRPOS). A multidisciplinary group of registered nurses, nurse practitioners, neonatologists, developmental specialists, and feeding specialists at five academic medical centers participated in the PRPOS development, which included five phases: (1) identification of domains, items, and responses; (2) item classification and selection using a modified Delphi process; (3) focus group exploration of items and response options; (4) cognitive interviews on a preliminary scale; and (5) final revision before field testing. Results Each phase of the process helped us to identify, classify, review, and revise possible domains, questions, and response options. The final items for field testing include 26 questions or observations that a nurse assesses before, during, and after routine care time and feeding. Conclusions We successfully created a prototype scale using modified PROMIS methodology. This process can serve as a model for the development of proxy-reported outcomes scales in other pediatric populations.
MAKTABGACHA TARBIYA YOSHIDAGI BOLALARDA BILISH JARAYONLARINING RIVOJLANISH XUSUSIYATLARI
Creators: name: Erkinova, Sevara Najmiddin Qizi
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: bilish
sezgi
idrok
bola
o„yin
faoliyat
akseleratsiya
psixika.

description: Maqolada psixologiyada bilish jarayonlarining tasnifi va ularning maktabgacha ta‟lim muassasalarida tarbiyalanayotgan bolalarda namoyon bo„lish shart-sharoitlari nazariy tahlillar asosida yoritib berilgan.
Investing in the middle : individual and investment ownership trends in St. Louis’ middle neighborhoods
Creators: name: Hartnett, Caitin
Publisher: name: The University of Texas at Austin
Year: 2021
Subjects: Middle neighborhoods
St. Louis
Affordable housing
Absentee ownership
Owner-occupancy
Legacy cities

description: Middle neighborhoods – neighborhoods that are “not in deep distress, but are not thriving either,” (Brophy, 2016) – have emerged as a recent point of interest for scholars interested in studying American cities in the Midwest and Northeast due to their potential to provide market-rate affordable housing options, particularly homeownership opportunities, to median and low-income residents. However, their relative affordability and stability in the housing market also makes them attractive to real estate investors. Because of their age, most housing units in middle neighborhoods require maintenance and upkeep and are thus vulnerable to decline due to neglect. Absent investor ownership is a point of concern for middle neighborhoods in many cities, making owner-occupancy an important factor for neighborhood stewardship. Using St. Louis as a case study, this report seeks to evaluate the extent to which homeownership and investor ownership has changed in the city’s middle neighborhoods since the onset of the financial crisis and offer suggestions to strengthening middle neighborhood housing markets. In doing so, it hopes to speak to the literature on housing financialization within the context of smaller cities and middle neighborhoods. In the absence of a formal qualitative definition for middle neighborhoods, the Market Value Analysis technique, developed by the Reinvestment Fund identified St. Louis’ middle neighborhoods using 2019 data. Subsequent analysis of investor sales from 2007-2019 showed a net loss of homeowners since the onset of the financial crisis and that middle neighborhoods have been epicenters for investor sales in the city. To maintain the quality of its middle neighborhoods, St. Louis must continue to engage in placemaking and placekeeping practices to develop desirable neighborhood narratives, expand opportunities for homeownership, and enforce property maintenance codes to curb negative repercussions that may emerge from absentee investor ownership.
Acanthospermum hispidum DC.
Creators: name: Sheded, Mohamed G.
name: Ayed, Fatma A. A.
name: Radwan, Tarek A. A.
name: Ahmed, Dalia A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Acanthospermum
Acanthospermum hispidum

description: Acanthospermum hispidum DC.
 The genus name of this species is derived from the Greek terms ákanthos and sperma, which respectively mean “thorn” and “seed” (Cunha 1982); hispidum is derived from Latin and means “rough” (relating to the rough hairs covering the seed) (Araújo et al. 2008). Common names of the plant are: Star burr, bristly starbur, goat’s head, Texas cockspur (Holm et al. 1997). The description (morphology) and dissemination of achenes of the plant are the same as in Beentje et al. (2005) and Thulin (2006).
 The earliest report of the discovery of A. hispidum was made in South America and it was published by De Candolle (1836: 522). It is currently present in more than 60 nations (NGRP 2014, USDA-ARS 2005). The species was recorded as naturalised for the first time in eastern Sudan (Elkhalifa et al. 2003), Asia, and Australia. Although it is primarily found in tropical and subtropical regions. According to the earlier reports (between 1914 and 1918), the species was transported from South America to Egypt as horse fodder. It has reached western Sudan, where it can turn into a problematic weed (Fairbairn 1940).
description: Published as part of Sheded, Mohamed G., Ayed, Fatma A. A., Radwan, Tarek A. A. & Ahmed, Dalia A., 2024, Contribution to Egypt's Flora: new records from Nile Islands, South Valley, Egypt, pp. 22-34 in Phytotaxa 660 (1) on page 30, DOI: 10.11646/phytotaxa.660.1.2, http://zenodo.org/record/13217982
Socioeconomic factors and self-reported health outcomes in African Americans with rheumatoid arthritis from the Southeastern United States: the contribution of childhood socioeconomic status
Creators: name: Callahan, Leigh
name: Jonas, Beth L
name: Cleveland, Rebecca J
name: Baldassari, Antoine R
name: Luong, My-Linh N
Publisher: name: BioMed Central
Year: 2016

description: Abstract Background There is abundant evidence that low socioeconomic status (SES) is associated with worse health outcomes among people with Rheumatoid Arthritis (RA); however, the influence of socioeconomic disadvantage in early life has yet to be studied within that population. Methods Data originated from the cross-sectional arm of the Consortium Evaluation of African-Americans with Rheumatoid Arthritis (CLEAR II), which recruited African-Americans with RA from six sites in the Southeastern United States. We used linear regression models to evaluate associations of parental homeownership status and educational level at participant time of birth with participant-reported fatigue (Visual Analog scale, cm), pain (Visual Analog scale, cm), disability (Health Assessment Questionnaire) and helplessness (Rheumatology Attitudes Index), independently of participant homeownership status and educational level. Models included random effects to account for intra-site correlations, and were adjusted for variables identified using backward selection, from: age, disease-duration, sex, medication use, body-mass index, smoking history. Results Our sample included 516 CLEAR II participants with full data on demographics and covariates. 89 % of participants were women, the mean age was 54.7 years and mean disease duration was 10.8 years. In age adjusted models, parental non-homeownership was associated with greater fatigue (β = 0.75, 95 % CI = 0.36–1.14), disability (β = 0.12, 95 % CI = 0.04–0.19) and helplessness (β = 0.12, 95 % CI = 0.03–0.21), independently of participant homeownership and education; parental education had a further small influence on self-reported fatigue (β = 0.20, 95 % CI = 0.15–0.24). Conclusions Parental homeownership, and to a small extent parental education, had modest but meaningful relationships with self-reported health among CLEAR II participants.
Differentiable rendering for synthetic aperture radar imagery
Creators: name: Wilmanski, Michael Charles
name: 0000-0002-0929-9884
Publisher: name: The University of Texas at Austin
Year: 2021
Subjects: Differentiable rendering
Synthetic aperture radar
SAR
3D reconstruction

description: Deep Neural Networks (DNNs) have been at the forefront of modern advancements in computer vision. In recent years, there have been efforts to incorporate more domain knowledge into DNN training and architectures by inserting signal processing functions into optimization pipelines. This can lead to DNNs that are trained more robustly and with limited data, as well as the capability to solve challenging inverse problems. Consequently, there is increasing interest in differentiable rendering, which allows explicitly modeling geometric priors and constraints into an optimization pipeline. Existing efforts in differentiable rendering have focused on imagery from electro-optical sensors, particularly conventional RGB-imagery. In this report, I propose an approach for differentiable rendering of Synthetic Aperture Radar imagery and demonstrate proof-of-concept experiments for the proposed method on the inverse problem of 3D Object Reconstruction. I also discuss limitations of the approach and next steps for future work.
Inaudibility of sixth order curvature invariants
Creators: name: Arias-Marco, Teresa
name: Schueth, Dorothee
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 58J50, 58J53, 53C25, 53C30, 53C20, 22E25

description: It is known that the spectrum of the Laplace operator on functions of a closed Riemannian manifold does not determine the integrals of the individual fourth order curvature invariants $\operatorname{scal}^2$, $|\operatorname{ric}|^2$, $|R|^2$, which appear as summands in the second heat invariant $a_2$. We study the analogous question for the integrals of the sixth order curvature invariants appearing as summands in $a_3$. Our result is that none of them is determined individually by the spectrum, which can be shown using various examples. In particular, we prove that two isospectral nilmanifolds of Heisenberg type with three-dimensional center are locally isometric if and only if they have the same value of $|\nabla R|^2$. In contrast, any pair of isospectral nilmanifolds of Heisenberg type with centers of dimension $r>3$ does not differ in any curvature invariant of order six, actually not in any curvature invariant of order smaller than $2r$. We also prove that this implies that for any $k\in\Bbb N$, there exist locally homogeneous manifolds which are not curvature equivalent but do not differ in any curvature invariant of order up to $2k$.
description: 24 pages
MAKTABGACHA YOSHDAGI BOLALARNI ASOSIY HARAKATLARGA O‘RGATISH USLUBIYATI
Creators: name: M. Nuriddinova
name: A. Bobomurodov
name: H. Kenjayeva
name: R. Xursanova
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: jismoniy faoliyat
asosiy harakat turi
ertalabki badantarbiya
o‗yin
mashg‗ulot
chiniqtirish
saflanish
gimnastika.

description: Ushbu maqolada maktabgacha yoshdagi bolalar bilan asosiy harakatlarni tashkil qilish bo‗yicha ma‘lumotlar keltirilgan.
A model for Rayleigh-Bénard magnetoconvection
Creators: name: Basak, Arnab
name: Kumar, Krishna
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: A model for three-dimensional Rayleigh-Bénard convection in low-Prandtl-number fluids near onset with rigid horizontal boundaries in the presence of a uniform vertical magnetic field is constructed and analyzed in detail. The kinetic energy $K$, the convective entropy $Φ$ and the convective heat flux ($Nu-1$) show scaling behaviour with $ε= r-1$ near onset of convection, where $r$ is the reduced Rayleigh number. The model is also used to investigate various magneto-convective structures close to the onset. Straight rolls, which appear at the primary instability, become unstable with increase in $r$ and bifurcate to three-dimensional structures. The straight rolls become periodically varying wavy rolls or quasiperiodically varying structures in time with increase in $r$ depending on the values of Prandtl number $Pr$. They become irregular in time, with increase in $r$. These standing wave solutions bifurcate first to periodic and then quasiperiodic traveling wave solutions, as $r$ is raised further. The variations of the critical Rayleigh number $Ra_{os}$ and the frequency $ω_{os}$ at the onset of the secondary instability with $Pr$ are also studied for different values of Chandrasekhar's number $Q$.
description: 11 pages (To appear in EPJB)
Geranium carolinianum
Creators: name: Sheded, Mohamed G.
name: Ayed, Fatma A. A.
name: Radwan, Tarek A. A.
name: Ahmed, Dalia A.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Geraniales
Geraniaceae
Geranium
Geranium carolinianum

description: Geranium carolinianum L.
 The common names of G. carolinianum are Carolina crane’s-bill, Carolina Geranium, and Wild Geranium (University of Texas 2023). The description of the recorded plant follows that in Blanchan (1916), Yeo (1984), and North Carolina Extension Gardener Plant Toolbox (North Carolina State University 2023). It was recorded for the first time in North Carolina (Chayka 2023) and was described by Linnaeus (1753: 682).
 In the United States, G. carolinianum has long been regarded as a weed that thrives in disturbed environments such as roadside ditches, gardens, abandoned fields, turfs, and uncultivated and fallow land (Gama-Archchige et al. 2010). It may have been introduced to Egypt with trading ships from China and India passing in the Red Sea and Suez Canal (Author conclusion). It prefers full sun to partial shade in gravelly, sandier, or hardpan clay-containing poorer soil. As a result, there will be less plant competition. Although this plant is offered for sale commercially, reseeding has the potential to make it weedy. Where it is naturally occurring it should be used for the greatest benefits. Birds will consume the seeds, while bees and other pollinators will visit the blossoms (Gama-Archchige et al. 2010).
description: Published as part of Sheded, Mohamed G., Ayed, Fatma A. A., Radwan, Tarek A. A. & Ahmed, Dalia A., 2024, Contribution to Egypt's Flora: new records from Nile Islands, South Valley, Egypt, pp. 22-34 in Phytotaxa 660 (1) on page 30, DOI: 10.11646/phytotaxa.660.1.2, http://zenodo.org/record/13217982
Macro-level factors impacting geographic disparities in cancer screening
Creators: name: Kuo, Tzy-Mey
Publisher: name: Springer
Year: 2014

description: Abstract Objectives Examine how differences in state regulatory environments predict geographic disparities in the utilization of cancer screening. Data sources/setting 100% Medicare fee-for-service population data from 2001-2005 was developed as multi-year breast (BC) and colorectal cancer (CRC) screening utilization rates in each county in the US. Study design A comprehensive set of supply and demand predictors are used in a multilevel model of county-level cancer screening utilization in the context of state regulatory markets. States dictate insurance mandates/regulations and whether alternative providers (nurse practitioners) can provide preventive care services supplied by MDs. Controlling statistically for the supply of both types of providers, we study the joint effects of two private insurance regulations: one mandating that insureds with serious or chronic health conditions may receive continuity of care from their established physician(s) after changing health insurance plans, and another mandating that external grievance review is an option for all health plan coverage/denial decisions. These private insurance plan regulations are expected to affect the degree of beneficial spillovers from managed care practices, which may have increased area-wide cancer screening rates. Principal findings The two private insurance regulations under study were significant predictors impacted by local market conditions. Managed care spillovers in local markets were significantly associated with higher BC screening rates, but only in states lacking the two forms of regulation under study. Spillovers were significantly associated with higher CRC cancer screening rates everywhere, but much higher in the unregulated states. Area poverty dampened screening rates, but less so for CRC screening in the states with these regulations. Conclusions Two state insurance regulations that empowered consumers with more autonomy to make informed utilization decisions varied across states, and exhibited significant associations with screening rates, which varied with the degree of managed care penetration or poverty in the state’s counties. Beneficial spillover effects from managed care practices and negative influences from area poverty are not uniform across the United States. Both variables had stronger associations with CRC than BC screening utilization, as did state regulatory variables. CRC screening by endoscopy was more subject to market and regulatory factors than BC screening.
Supplementary document for Vectorial inverse scattering for dielectric tensor tomography: overcoming challenges of reconstruction of highly scattering birefringent samples - 6518401.pdf
Creators: name: Hugonnet, Herve
name: Lee, Moosung
name: Shin, Seungwoo
name: Park, YongKeun
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplemental Document
SEMANTIC FIELDS OF PHRASEOLOGICAL UNITS
Creators: name: Qurbonova, Nigina Xolmurod Qizi
name: Marjona Abdunazar Qizi Abdumajidova
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: Semantics
collocations
proverbs
sayings
analysis
morpheme
metaphor.

description: This article is dedicated to semantic field of phraseological units, definition and translation of some words.
Time of our lines : time use patterns and transit use
Creators: name: LaRue, Seth
name: 0000-0002-3239-4003
Publisher: name: The University of Texas at Austin
Year: 2021
Subjects: Transit
Time use
American time use survey

description: This report compares time use patterns of those who do and do not use public transit in the American Time Use Survey (ATUS). It theorizes that people who ride transit require flexibility as part of using that system. Using data about work schedules as well activity patterns, the report measure differences across categories of time use that serve to indicate flexibility or inflexibility. The study posits that, as life grows more hurried, time inflexibility forces public transit users to make difficult decisions on how to manage their time. When these forces become too disruptive, public transit users may stop riding, leading to a loss of mode share and revenue for a vital public service. This analysis yields some evidence that public transit users spend less time on leisure activities than do non-public transit users. Additionally, travel time measures indicate that leisure activities are the hardest to reach by public transit further limiting PT users to participate in these activities. On the other hand, there is evidence that public transit users inoculate themselves against these time deprivations by not owning a home, living in more accessible areas, and avoiding life cycle constraints on flexibility associated with marriage and children. Planners interested in maintaining public transit mode share should consider how best to support these lifestyle decisions while providing a service which better serves public transit users.
Decay analysis of compound nuclei with mass A$\sim 30-200$ formed in the reactions involving loosely bound projectiles
Creators: name: Kaur, Mandeep
name: Singh, BirBikram
name: Sharma, Manoj K.
name: Gupta, Raj K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The dynamics of the reactions forming compound nuclei using loosely bound projectiles is analysed within the framework of dynamical cluster decay model (DCM) of Gupta and Collaborators. We have analysed different reactions with $^{7}Li$, $^{9}Be$ and $^{7}Be$ as neutron rich and neutron deficient projectiles, respectively, on different targets at the three $E_{lab}$ values, forming compound nuclei within the mass region A$\sim 30-200$. The contributions of light particles LPs ($A\le4$) cross sections $σ_{LP}$, energetically favoured intermediate mass fragments IMFs ($5 \le A_2 \le 20$) cross sections $σ_{IMF}$ as well as fusion-fission $\it{ff}$ cross sections $σ_{ff}$ constitute the $σ_{fus}$ (=$σ_{LP}$+$σ_{IMF}$+$σ_{ff}$) for these reactions. The contribution of the emitted LPs, IMFs and ff fragments is added for all the angular momentum upto the $\ell_{max}$ value, for the resepctive reactions. Interestingly, we find that the $ΔR^{emp}$, the only parameter of model and uniquely fixed to address the $σ_{fus}$ for all other reactions having $\it same$ loosely bound projectile at the chosen incident energy. It may be noted that the dynamical collective mass motion of preformed LPs, IMFs and ff fragments or clusters through the modified interaction potential barrier are treated on parallel footing. We see that the values of modified interaction barrier heights $ΔV_{B}^{emp}$ for such reactions are almost of the same amount specifically at the respective $\ell_{max}$ values.