cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Imaging glycogenesis as a novel biomarker of drug-induced senescence/quiescence
Creators: name: Chen, Cen
Publisher: name: Imperial College London
Year: 2020

description: Cellular senescence, which is a state of irreversible growth arrest in response to diverse stimuli, has been implicated in many age-related diseases and shown to play complex roles in tumorigenesis. Since the first description of senescence by Hayflick and colleagues in 1961, significant progress has been made in understanding the characteristics and functions of cellular senescence. However, efforts to identify senescence remain limited due to a lack of robust and universal biomarkers for this cell fate. As enhanced glycogenesis has been associated with cell growth arrest, it has been hypothesized in this thesis that PET imaging agents that measure glycogenesis could be a potential tool for assessment of senescence-directed anticancer therapies. The profile of glycogenesis of a panel of cancer cell lines characterised by various genetic backgrounds was first assessed. Cancer cell lines showed distinct patterns of glycogenesis, among which an AKT-GSK3β-dependent regulation of glycogen synthase (GYS1) through PI3K pathway was observed in PTEN-null tumour cells. A cell growth-related regulation of glycogenesis was found in the tested cells, in which cells when cultured under the G0/G1 phase arrest increased glycogen synthesis via a GYS1-dependent manner and thereby led to an increase in glycogen accumulation. Moreover, tumour cells under hypoxic condition were more susceptible to GYS1 knockdown as glycogenesis was more significantly attenuated under hypoxia than normoxic condition. Additionally, one of the four tested anticancer drugs, namely palbociclib, was shown to dose- and time-dependently induce senescence in ER-positive breast cancer cell lines in vitro, as shown by the presence of senescence-like morphology, increased SA-β-gal activity and upregulation of p21 expression. An increase in glycogenesis was found in response to palbociclib treatment via a G6P-dependent elevation in GYS1 activity. Correspondingly, 18F-NFTG, a glycogenesis-based PET radiotracer previously developed by our group, was largely accumulated in palbociclib-induced quiescent/senescent cells. To extend the exploration, the attempts were made to develop and evaluate a novel senescence-specific probe based on detection of lipofuscin formation. Not only did the non-radioactive reference compound [19F]FET-SBB show specific staining of lipofuscin aggregates in palbociclib-treated cell, but also the radiolabelled [18F]FET-SBB was significantly retained, suggesting potential application of [18F]FET-SBB in targeting senescence. In summary, while senescence mechanisms can be varied, drug-induced senescence is detectable in vitro as increased glycogenesis and lipofuscin formation in some contexts. These methods described here have potential for translation in vivo.
Cofactor analogue chemoproteomics for identification of PLP-binding proteins and characterisation studies on fold type III PLP-binding proteins in M. tuberculosis
Creators: name: Homsak, Miha
Publisher: name: Imperial College London
Year: 2020

description: Pyridoxal 5’-phosphate (PLP) is an essential enzyme cofactor required for the correct functioning of PLP-dependent enzymes (PLP-DE), which catalyse a plethora of vital cellular processes. PLP-DE are ubiquitously present in all living organisms, including pathogens such as Mycobacterium tuberculosis (Mtb). Understanding their role in pathogen biology could significantly advance our understanding of the pathogen and facilitate the discovery of novel therapeutic agents. In this doctoral thesis, the development of an activity-based profiling approach for the identification of PLP-DE in Mtb is described. After synthesising a PLP analogue chemical probe, it was used in chemical proteomics experiments where selective enrichment of PLP-DE was achieved and 51 % of predicted Mtb PLP-DE could be identified. Two of the identified proteomics hits, Rv1769 and Rv2148c, were completely unannotated proteins that have not been computationally predicted to bind PLP. In a series of follow-up experiments, Rv2148c was expressed and purified, and some of its biophysical parameters as well as its crystal structure were determined, which confirmed that Rv2148c does indeed bind a PLP molecule and that it is a fold type III PLP-DE. Several attempts to determine the function of Rv2148c were made, but this remains a work in progress. In addition, a secondary project focusing on the mode of action of D-cycloserine (DCS), an Mtb antibiotic, was undertaken. DCS was thought to irreversibly inactivate Mtb alanine racemase (MtAlr), a fold type III PLP-DE, by forming a covalent adduct with PLP. However, after realising that MtAlr is not fully inhibited in vivo, a systematic study to reveal the mechanism of inhibition was undertaken. It was found that the PLP-DCS adduct can undergo hydrolysis, which is followed by chemical rearrangement and release of the product into the cellular milieu, leading to the reactivation of MtAlr. DCS inhibition was therefore found to be a reversible process.
Rapid and efficient thiocyanation of phenols, indoles and anilines in 1,1,1,3,3,3-hexafluoro-2-propanol under ultrasound irradiation
Creators: name: Wang, Zhonghao
name: Wang, Liang
name: Chen, Qun
name: He, Ming-yang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Space Science
Medicine
Molecular Biology
Neuroscience
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Marine Biology
Mental Health
Computational Biology

description: An efficient ultrasound-promoted thiocyanation of phenols, indoles and anilines in the presence of N-chlorosuccinimide (NCS) and NH4SCN using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as the solvent has been developed. The major features of the present protocol include the mild reaction conditions, short reaction times, good to excellent yields and broad substrate scope. Moreover, scale-up synthesis can be achieved and the solvent can be easily recovered and reused.
title: Patienten mit diabetischem Makulaödem – schwerer krank als gedacht? Erste Ergebnisse der Lipsia-Studie
Creators: name: Jochmann, Claudia
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Das diabetische Makulaödem ist im Zeitalter der intravitrealen Medikamenteninjektionen die am häufigsten behandelte Komplikation der diabetischen Retinopathie. Wann und warum ein Patient ein diabetisches Makulaödem entwickelt und wie viele Injektionen notwendig sind, ist bisher nicht [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
Уровень 25(ОН) витамина D и компоненты метаболического синдрома у женщин репродуктивного возраста при различном генотипе ApaI полиморфизма гена рецептора витамина D.pdf
Creators: name: Doe, Jonn
Publisher: name: figshare
Year: 2017
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: Cardiology
subject: 110201 Cardiology (incl. Cardiovascular Diseases)

description: Уровень 25(ОН) витамина D и компоненты метаболического синдрома у женщин репродуктивного возраста при различном генотипе ApaI полиморфизма гена рецептора витамина D
Flamenco and the Music of Manuel de Falla: A Piano Perspective
Creators: name: Zen Zeng
Publisher: name: Monash University
Year: 2019
Subjects: Uncategorized

description: Twentieth-century Spanish piano music is significantly shaped by the works of Manuel de Falla. The Spanish composer’s classical stylization of flamenco marks a profound marriage between piano and flamenco, and remains a significant reference for contemporary musicians of Western art music and flamenco. However, performers of Falla’s early twentieth century piano repertoire often fail to take into account the evolving nature of flamenco, as well as the composer’s understanding and intended use of flamenco materials in each compositional period, leading to interpretations shaped by stereotypes of the exotic and passionate images of Andalusia. This study argues that there is no stereotypical ‘Spanish’ template for interpreting fin-de-siècle Spanish piano repertoire, and challenges prescribed interpretations of Falla’s piano music.

 Building on my own performance practice of both piano flamenco and fin-de-siècle Spanish piano music, this study undertakes a close musical examination of the evocations of flamenco idioms in Falla’s music, discusses the identification and interpretation of a range of flamenco idiosyncrasies in Falla’s music scores, and interrogates how Falla’s adaptations of flamenco evolved as his compositional vocabulary expanded. By providing critical commentaries on iconic and historical recordings of Falla’s piano music, this study subsequently offers some new practical performance strategies to interpreters of this repertoire.
title: Venenverschlüsse und Laser
Creators: name: Rehak, Matus
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Fokale (gitterförmige) Laserphotokoagulation galt vor Einführung der intravitrealen Injektionstherapie (IVOM) als Goldstandard für die Behandlung des Makulaödems infolge eines Venenastverschlusses. Indiziert wurde sie bei Patienten mit einem Visus von ≤0,5, bei denen das Ödem[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
On the (110) Surface Structure of ZIF-8
Creators: name: Slater, Ben
name: Sanliang Ling
name: Hart, Martin
name: Salzmann, Christoph G.
Publisher: name: figshare
Year: 2017
Subjects: subject: 30307 Theory and Design of Materials
subject: FOS: Chemical sciences
subject: 91205 Functional Materials
subject: FOS: Materials engineering
subject: 30304 Physical Chemistry of Materials

description: Computational results on the external surface structure of ZIF-8
title: Nebenwirkung der systemischen Sicca-Therapie
Creators: name: Müller, Philipp
name: Terai, N.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Keratokonjunktivitis Sicca ist ein häufiges okuläres Krankheitsbild, welches mit erheblicher Beschwerdesymptomatik und Einschränkung der Lebensqualität einhergehen kann. Neben der Vermeidung von Umwelt-/Risikofaktoren kommen Tränenersatzmittel und die Lidrandhygiene[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
East Hampton Village Police Force, August 5, 1948
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 1948
Subjects: East Hampton
Police

description: This image shows the East Hampton Village Police Force gathered for a group picture on August 5, 1948. The two men standing in front of the group are Richard Steele on the left and Chief Francis "Fritz" Leddy on the right. The men in the back row are, from left to right: Joseph Loris, Richard Mott, Arthur Conklin, Tom Mott and Jack Mahoney.
Effect of agent concentration in ultrasound super- resolution imaging at clinically low frequency
Creators: name: Zhu, Ziyan
Publisher: name: Imperial College London
Year: 2021

description: Imaging of microvasculature can be valuable for the diagnosis and treatment monitoring of cancer and other diseases. Ultrasound has the potential due to its excellent spatial and temporal resolution. Super-resolution ultrasound imaging using contrast enhanced ultrasound localization microscopy is able to visualize microvasculature beyond the wave diffraction limit. The microbubble based super-resolution depends on controlling the bubble concentration, which needs to be low enough to locate isolated microbubbles. However too low a concentration will prolong the data acquisition. The aim of the thesis was to evaluate the impact of microbubble concentration on super-resolution ultrasound imaging, and to improve the signal processing in super-resolution imaging. First, various concentrations of microbubble contrast agents (6×10^3 to 1.5×10^6particles/ml) were injected into a 200 microns cross-tube flow phantom. The experimental results show that the concentration affects the resolution of the cross-tube images. When the concentration is lower than the 1.5×10^5particles/ml, two tubes in a selected region of interest near the intersection that are 370 microns apart can be separated, which is close to the expected distance (390 microns). Second, the comprehensive effects of data acquisition time and concentration on imaging resolution were studied. The preferred range of concentration was determined between 1.5×10^4 to 6×10^4particles/ml. This result can be used to better inform data acquisition in the further research. Third, a weight adaptive denoising method based on morphology was developed to remove noises which were produced in the step of microbubble detection at the preferred range of concentration. Therefore, the resolution and the accuracy of the velocity map were further improved.
title: Fourier-Deligne transformation of perverse sheaves and the change of Frobenius traces under the Katz algorithm
Creators: name: Tenzler, Julian
Publisher: name: University of Bayreuth
Year: 2020
Subjects: subject: Katz algorithm
subject: Frobenius trace
subject: perverse sheaves
subject: 510

description: The classical Katz algorithm gives an answer to the "Irreducible Recognition and Construction Problem" which asks whether a given set of local monodromy representations comes from an irreducible and rigid l-adic local system. The algorithm submits perverse sheaves, a generalization of local systems, defined over algebraically closed fields to a sequence of middle convolution and tensor products. Dettweiler and Reiter introduced the idea to use the reverse of this algorithm to construct rigid local systems which give rise to new realizations of certain groups as Galois groups over the rational numbers. In this work we make the shift to perverse sheaves defined over finite fields. This enriches the local monodromy data with traces of geometric Frobenius elements. Using work of Katz and Laumon we study the relation between middle convolution and Laumon's (local) Fourier-Deligne transformation and give explicit formulars for the changing behavior of the local monodromy and the Frobenius data of a certain subcategory of the perverse sheaves along the individual steps of the Katz algorithm. This provides new tools for studying the middle convolution over finite fields and realizing new groups as Galois groups over the rational numbers.
Controls on groundwater and surface water salinity in coastal Bangladesh
Creators: name: Tsai, Chi-San
Publisher: name: Imperial College London
Year: 2021

description: Salinity in surface water and groundwater is a pervasive issue along coastal Bangladesh, a low-lying megadelta where around 35 million people live. A large amount of this land has been reclaimed using a network of low-lying polders. The area is particularly susceptible to flooding from tropical cyclones. Cyclone induced storm surges coupled with the low-lying reclaimed land can breach polder embankments and cause extensive flooding, resulting in excess salinity in soil and surface water. Salinity in drinking water is known to cause adverse effects on human health. It is, therefore, important to identify the controls surface water and groundwater salinity in these coastal areas. A fully coupled surface-subsurface model of a coastal polder by using HydroGeo- Sphere is developed to investigate the impact of storm surge events on groundwater salinity. The hydrological parameters were calibrated from the fieldwork at a field site in the Dacope Upazila, in the southwest coastal region of Bangladesh. The results suggest that sudden salt fluxes in the pond are likely to build up salinity in the underlying sediment. A set of scenarios were considered: a cyclone induced storm surge during both the monsoon and dry seasons, and both with and without remediation. The results show that surge events caused a rise in salinity in drinking water and near-surface groundwater. However, rapid remediation after a surge event could help mitigate the severity of the impact on drinking water. This provides suggestions for water resources management planning. The 2D cross-section model was extended to the 3D model to improve the understanding of the salinity process. Climate change scenarios were then used to evaluate the effects of episodic cyclone surges on shallow groundwater salinity. This study suggests that more frequent cyclones would worsen not only salinity in near-surface groundwater but lateral saltwater intrusion at the shallow or deep aquifers.
title: Eid and son
Creators: name: Langage, Langues Et Cultures D'Afrique
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: anthropological_linguistics
subject: tale
subject: Beja
subject: bej
subject: Annotation

description: Recording session done by the collector/researcher in the speaker's house. Were present : the colector/researcher and the speaker.
description: Two men are quarrelling about the parternity of a boy. "Observers" whom they consult find the soltution.
description: Conforms to: Leipzig Glossing Rules
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
The Brain Imaging Data Structure: a simple way to share data
Creators: name: Pernet, Cyril
Publisher: name: figshare
Year: 2017
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: In this talk I present and discuss BIDS, the brain imaging data structure, and why/how it's adoption in the imaging community is happening. What are the good things that allowed imaging researchers to adopt that standard.
Work presented at the Software Sustainability Institute Collaborative Workshop on 27th March 2017
title: Transkanalikuläre Operationsverfahren bei angeborenen Tränenwegsstenosen
Creators: name: Sommer, Falk
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Tränenabflussstörungen treten mit erhöhter Inzidenz auf. Während bei angeborenen Tränenweg- (TNW) obstruktionen genetische Faktoren und auch die Entbindung durch Kaiserschnitt eine Rolle spielen, stehen bei erworbenen Tränenwegstenosen demografische Faktoren[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
Çatalhöyük Area TP Main Zooarchaeological Dataset (Secure contexts) [Structured Data from Open Context]
Creators: name: Arek Marciniak
name: Nerissa Russell
name: Kamilla Pawlowska
name: Katheryn Twiss
name: Liz Henton
name: David Orton
name: Arzu Demirergi
name: Louise Martin
name: Banu Aydinuloglu
name: Claire Christensen
name: Ian Cameron
name: Sheelagh Frame
name: Rebecca Daly
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Çatalhöyük Area TP Main Zooarchaeological Dataset (Secure contexts) Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 35-catalhoyuk-area-tp-main-zooarchaeological-dataset-secu.csv contains the tabular data content for this resource in a CSV format.
JSON: The 35-catalhoyuk-area-tp-main-zooarchaeological-dataset-secu.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
Data for large carnivores as socioecological keystone species
Creators: name: Williams, Katy
Publisher: name: figshare
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 50202 Conservation and Biodiversity
subject: 50102 Ecosystem Function
subject: FOS: Earth and related environmental sciences

description: Data for large carnivores as socioecological keystone species
Balance of disinfection and cytotoxicity of hydroxypropyltrimethyl ammonium chloride chitosan with polyhexamethylene biguanide at low concentrations
Creators: name: Wang, Huafu
name: Yao, Chen
name: Qian, Kun
name: Guo, Qing
name: Shu, Weixia
name: Chen, Ping
name: Song, Wei
name: Wang, Yihong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Any microorganisms killing molecules have some cytotoxicity more or less. The effective way of reducing cytotoxicity mainly included two approaches: One was reducing the concentration of antiseptic, while this would lead to the decreased antimicrobial efficiency; the other way was choosing suitable antiseptics and then combining of them, which can balance the disinfection and cytotoxicity. In this paper, hydroxypropyltrimethyl ammonium chloride chitosan (HACC), a cationic natural macromolecular, as the first antiseptic, incorporated with polyhexamethylene biguanide (PHMB), a smaller molecular weight cationic antiseptic polymer, as the second antiseptic, their disinfection effect and cell cytotoxicity in borate buffer solution were investigated at fairly low contents. When HACC/PHMB weight ratios were 100/1 and 150/1, the disinfection solutions produced >1-log reductions against C. albicans and >3-log reductions against S. aureus and P. aeruginosa. HACC/PHMB disinfection solution at weight ratio of 150/1 even showed a highest antimicrobial efficiency and the cell proliferation rates were approximately 100% in MTT assays. Meanwhile, the research of micromorphology and fluorescence spectra indicated that bigger aggregation state of HACC-PHMB were helpful to improve antimicrobial ability. These results showed that the HACC-PHMB combination might be a promising candidate for novel antimicrobial group for biomedical applications.
title: Quarrel between two tribes
Creators: name: Langage, Langues Et Cultures D'Afrique
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: anthropological_linguistics
subject: Anecdote
subject: Beja
subject: bej
subject: Annotation

description: Recording session done by the collector/researcher in Khartoum. Were present : the colector/researcher, and the speaker.
description: Two tribes are quarrelling aver the ownership of a camel. It is a piece of flesh that one tribes man recongizes that reveals who the real owner is.
description: Conforms to: Leipzig Glossing Rules
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Implementing Results-Based Management in international- and SFPA waters: lessons learned in pilot studies
Creators: name: Aschan, Michaela
name: Boampong, Joshua
name: Nielsen, Kåre Nolde
name: Mikkelsen, Nina
name: Rodriguez, Alexandre R.
name: Doblado, Sonia M.
name: Arias-Hansen, Juliana
name: Erzini, Karim
name: Viðarsson, Jónas R.
name: Friðriksdottir, Ragnhildur
name: Vidal, Duarte F.
name: Brahim, Khallahi
name: Diallo, Mamadou
name: Fonseca, Benvindo
name: Lucas, Vincent
name: Roucou, Yannick
name: Rincón Hidalgo, Margarita
Publisher: name: Zenodo
Year: 2021
Subjects: SFPA - Sustainable Fisheries Partnership Agreements
CFP - Common Fisheries Policy
Fisheries management

description: This report is the final deliverable of work package four (WP4) within the FarFish project. The WP is titled “Development of management recommendations” and has focused on developing so called Management Recommendations (MRs) within the FarFish case studies. The MR concept is based on Results-Based Management (RBM) approaches, with the aim to delegate management responsibilities to resource users. The aim or this report is to review the RBM process applied in FarFish and the lessons learned in the case studies. The report is in the format of a peer-review journal paper, which is planned to be submitted to a journal shortly. Chapter 2 contains the paper.
Информационная культура как фактор трансформации идентификационной парадигмы
Creators: name: Лисенкова Анастасия Алексеевна
Publisher: name: Культурная жизнь Юга России
Year: 2017
Subjects: ИДЕНТИФИКАЦИЯ
ИНФОРМАЦИОННОЕ ОБЩЕСТВО
ИДЕНТИФИКАЦИОННАЯ ПАРАДИГМА

description: В статье акцентировано внимание на процессах изменения идентификационной парадигмы в условиях трансформирующегося общества. Раскрываются процессы, оказывающие влияние на данное явление. Современные стратегии идентификации и репрезентации идентичности в глобальном пространстве сетевых медиа. Анализируется связь смены идентификационной парадигмы с визуальной культурой, потребностью в принадлежности и признании. Рассматривается текучесть, подвижность и множественность процессов идентификации в современных условиях турбулентного общества.
Efficient photocatalytic degradation of methyl violet with two metall–organic frameworks
Creators: name: Lu, Lu
name: Wang, Jun
name: Cai, Shu-Lan
name: Xie, Bin
name: Li, Bao-Hong
name: Man, Jian-Hui
name: He, Yong-Xiang
name: Singh, Amita
name: Kumar, Abhinav
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Two metal–organic frameworks, [Co2(L)(H2O)2(4,4′-bipy)]·3CH3CN (1) and [Mn2(L)(1,10-phen)(H2O)]·H2O (2) (H4L = 5-[bis(4-carboxybenzyl)-amino]isophthalic acid; 4,4′-bipy = 4,4′-bipyridine, 1,10-phen = 1,10-phenanthroline), with two different N-donor ligands have been synthesized. The structures of both MOFs were determined using single-crystal X-ray diffraction technique. MOF 1 shows 3D uncommon (4,6,6)-c net with (4.53.62)2(57.66.82)(42.54.66.72.8) topology while in the case of 2, only L4− ligands link Mn(II) ions into a 2D layer structure with chelating 1,10-phen ligand. The results demonstrate that variation in the N-donor ligands plays a pivotal role in deciding the framework of the two MOFs. Both MOFs have been exploited as photocatalyst materials for the degradation of MV. The photocatalysis results indicate that the two MOFs are stable and are prospective candidates for degradation of methyl violet under UV light irradiation. Additionally, 2 displayed superior photocatalytic activity in comparison to 1. The probable photocatalytic activity mechanism for both 1 and 2 against MV has been proposed using density of states (DOS) calculations.
Policy Challenges for Professional Higher Education in Central and South Eastern Europe
Creators: name: Camilleri, Anthony
name: Poličnik, Jasmina
name: Alicia Leonor Sauli Miklavčič,
name: Alupei-Durach, Flavia
name: Žarko Nožica
name: Ondřej Chrást
name: Voldánová, Iva
name: Karpíšek, Michal
name: Dinya, László
name: Medve, Anna
name: Wéber, György
name: Racsko, Réka
name: Perényi, Petra
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences

description: PROCSEE is a policy-oriented project, aimed at strengthening the provision of professional higher education, by strengthening the policy-work conducted by umbrella organizations representing professional higher education institutions in Central and South-Eastern in Europe.
Working together over three years, the project intends to:
 - identify the main challenges facing PHE in the region  propose policy solutions to address those challenges in the short-to-mid term, through a mixture of good-practice identification and stakeholder consultation- bring together the main actors in PHE in each participating country, so as to build implementation roadmaps for the identified policy solutions

The result of the first year of activities of the project, this document outlines the main challenges facing professional higher education in the CSEE region, with the aim of highlighting potential areas for reform in the next project phases.
title: Aimer Ja
Creators: name: Jaulin, Yannick
name: Costa, James
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: subject: Parlanjhe
subject: fra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Policy-Challenges-for-Professional-Higher-Education-in-Central-and-South-Eastern-Europe.pdf
Creators: name: Camilleri, Anthony
name: Poličnik, Jasmina
name: Alicia Leonor Sauli Miklavčič,
name: Alupei-Durach, Flavia
name: Žarko Nožica
name: Ondřej Chrást
name: Voldánová, Iva
name: Karpíšek, Michal
name: Dinya, László
name: Medve, Anna
name: Wéber, György
name: Racsko, Réka
name: Perényi, Petra
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences

description: PROCSEE is a policy-oriented project, aimed at strengthening the provision of professional higher education, by strengthening the policy-work conducted by umbrella organizations representing professional higher education institutions in Central and South-Eastern in Europe.
Working together over three years, the project intends to:
 - identify the main challenges facing PHE in the region  propose policy solutions to address those challenges in the short-to-mid term, through a mixture of good-practice identification and stakeholder consultation- bring together the main actors in PHE in each participating country, so as to build implementation roadmaps for the identified policy solutions

The result of the first year of activities of the project, this document outlines the main challenges facing professional higher education in the CSEE region, with the aim of highlighting potential areas for reform in the next project phases.
Efficient photocatalytic degradation of methyl violet with two metal-organic frameworks
Creators: name: Lu, Lu
name: Wang, Jun
name: Cai, Shu-Lan
name: Xie, Bin
name: Li, Bao-Hong
name: Man, Jian-Hui
name: He, Yong-Xiang
name: Singh, Amita
name: Kumar, Abhinav
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Two metal-organic frameworks, [Co2(L)(H2O)2(4,4’-bipy)]∙3CH3CN (1) and [Mn2(L)(1,10-phen)(H2O)]∙H2O (2) (H4L = 5-[bis(4-carboxybenzyl)-amino]isophthalic acid; 4,4’-bipy = 4,4’-bipyridine, 1,10-phen = 1,10-phenanthroline), with two different N-donor ligands have been synthesized. The structures of both MOFs were determined using single crystal X-ray diffraction technique. MOF 1 shows 3D uncommon (4,6,6)-c net with (4.53.62)2(57.66.82)(42.54.66.72.8) topology while in the case of 2, only L4- ligands link Mn(II) ions into a 2D layer structure with chelating 1,10-phen ligand. The results demonstrate that variation in the N-donor ligands plays a pivotal role in deciding the framework of the two MOFs. Both MOFs have been exploited as photocatalyst materials for the degradation of MV. The photocatalysis results indicate that the two MOFs are stable and are prospective candidates for degradation of methyl violet under UV light irradiation. Additionally, 2 displayed superior photocatalytic activity in comparison to 1. The probable photocatalytic activity mechanism for both 1 and 2 against MV have been proposed using density of states (DOS) calculations.
Risk assessment of dietary exposure to phytosterol oxidation products from baked food in China
Creators: name: Hu, Yinzhou
name: Wang, Mengmeng
name: Huang, Weisu
name: Yang, Guoliang
name: Lou, Tiantian
name: Lai, Shiyun
name: Lu, Baiyi
name: Zheng, Lufei
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Phytosterols are nutritional phytochemicals that may undergo oxidation and be transformed into phytosterol oxidation products (POPs), thus inducing pathological and toxic effects. This work investigated four main phytosterols and 28 POPs in 104 kinds of commercial baked food by using GC-MS. The dietary exposure and hazard index values (HI) associated with POPs from baked food consumption in China were estimated by using Monte Carlo simulation. Concentrations of the total phytosterols were between 3.39 and 209.80 μg/g. The total concentrations of POPs, including 5α,6α/5β,6β-epoxysterols, 7-ketosterol, 7α/7β-hydroxysterols, 6-hydroxysterols, and triols, ranged from 0.37 to 27.81 μg/g. The median dietary exposure of POP contents in baked food for four age groups in China were 10.91 (children), 6.20 (adolescents), 3.63 (adults), and 3.40 (seniors) mg/(kg×day). Risk assessment of median HI with respect to POPs indicated no risk (HI <1) for people in adolescents, adults, and seniors in the country area of China, while a risk (1 < HI < 10) would refer to the baked food consumption of people in urban area and children in country area of China. Sensitivity and uncertainty analysis showed that the most significant variables for each age group in China were POP concentration, body weight, and ingestion rate.
Ilıpınar Zooarchaeology Main Zooarchaeological Dataset [Structured Data from Open Context]
Creators: name: Hijlke Buitenhuis
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Ilıpınar Zooarchaeology Main Zooarchaeological Dataset Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 36-ilipinar-zooarchaeology-main-zooarchaeological-dataset.csv contains the tabular data content for this resource in a CSV format.
JSON: The 36-ilipinar-zooarchaeology-main-zooarchaeological-dataset.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
How to perform a cost-effectiveness analysis with surrogate endpoint: renal denervation in patients with resistant hypertension (DENERHTN) trial as an example
Creators: name: Bulsei, Julie
name: Darlington, Meryl
name: Durand-Zaleski, Isabelle
name: Azizi, Michel
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Whilst much uncertainty exists as to the efficacy of renal denervation (RDN), the positive results of the DENERHTN study in France confirmed the interest of an economic evaluation in order to assess efficiency of RDN and inform local decision makers about the costs and benefits of this intervention. The uncertainty surrounding both the outcomes and the costs can be described using health economic methods such as the non-parametric bootstrap. Internationally, numerous health economic studies using a cost-effectiveness model to assess the impact of RDN in terms of cost and effectiveness compared to antihypertensive medical treatment have been conducted. The DENERHTN cost-effectiveness study was the first health economic evaluation specifically designed to assess the cost-effectiveness of RDN using individual data. Using the DENERHTN results as an example, we provide here a summary of the principle methods used to perform a cost-effectiveness analysis.
title: Surfaces cultivées par circonscription. 1941-1948 / Densités d'habitants par superficie cultivée 1952
title: Surfaces cultivées par circonscription. 1941-1948 / Densités d'habitants par superficie cultivée 1952
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Agriculture

description: Cartographie
description: BESM-carto_1957-76-p491_76-02
description: 491
description: 76
description: Bulletin économique et social du Maroc
description: Source: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Source: Bulletin économique et social du Maroc
description: Source: Bulletin économique et social du Maroc (BESM) > BESM (Cartographie)
description: Relation: https://cinumed.mmsh.univ-aix.fr/idurl/1/81850
description: Coverage: Maroc
description: Coverage: XXe siècle
description: Temporal: XXe siècle
description: Bibliographic citation: « Surfaces cultivées par circonscription. 1941-1948 / Densités d'habitants par superficie cultivée 1952 », In Bulletin économique et social du Maroc (BESM), n° 76, 1957
description: Provenance: Maison méditerranéenne des sciences de l'homme, Cité numérique de la Méditerranée (Cinumed), Bibliothèque nationale du Royaume du Maroc (BNRM)
description: Provenance: https://cinumed.mmsh.univ-aix.fr/
Natural genetic variation in GLK1-mediated photosynthetic acclimation in response to light
Creators: name: Muino, Jose M.
name: Großmann, Christopher
name: Kleine, Tatjana
name: Kaufmann, Kerstin
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Natural variation
subject: Arabidopsis thaliana
subject: GLK1
subject: Acclimation
subject: 570 Biologie

description: The article processing charge was funded by the Open Access Publication Fund of Humboldt-Universität zu Berlin.
description: Background: GOLDEN-like (GLK) transcription factors are central regulators of chloroplast biogenesis in Arabidopsis and other species. Findings from Arabidopsis show that these factors also contribute to photosynthetic acclimation, e.g. to variation in light intensity, and are controlled by retrograde signals emanating from the chloroplast. However, the natural variation of GLK1-centered gene-regulatory networks in Arabidopsis is largely unexplored. Results: By evaluating the activities of GLK1 target genes and GLK1 itself in vegetative leaves of natural Arabidopsis accessions grown under standard conditions, we uncovered variation in the activity of GLK1 centered regulatory networks. This is linked with the ecogeographic origin of the accessions, and can be associated with a complex genetic variation across loci acting in different functional pathways, including photosynthesis, ROS and brassinosteroid pathways. Our results identify candidate upstream regulators that contribute to a basal level of GLK1 activity in rosette leaves, which can then impact the capacity to acclimate to different environmental conditions. Indeed, accessions with higher GLK1 activity, arising from habitats with a high monthly variation in solar radiation levels, may show lower levels of photoinhibition at higher light intensities. Conclusions: Our results provide evidence for natural variation in GLK1 regulatory activities in vegetative leaves. This variation is associated with ecogeographic origin and can contribute to acclimation to high light conditions.
title: Le bel osia
Creators: name: Jaulin, Yannick
name: Costa, James
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: subject: Parlanjhe
subject: fra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Comparison of trends and frequencies of drought in central North China and sub-Saharan Africa from 1901 to 2010
Creators: name: Katchele, Ogou Faustin
name: Ma, Zhu-Guo
name: Yang, Qing
name: Batebana, Kpaikpai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: This study compares the trends and frequencies of drought between central North China (CNC) and (SSA) for the periods 1901–2010 and 1951–2010. The Standardized Precipitation Evapotranspiration Index (SPEI) and Self-Calibrating Palmer Drought Severity Index (sc-PDSI) are used to assess the drought trends and frequencies. In general, the results exhibit downward trends of drought index values and upward trends of drought frequencies over CNC and SSA. A high rate of the trends’ slopes for the drought index and a low rate of the frequencies’ slopes is found over CNC with respect to SPEI and sc-PDSI. Furthermore, some abrupt changes are revealed after applying the sequential Mann–Kendall test to detect change points. These findings offer insight into the trends and frequencies of drought over the regions studied. Further analysis needs to be undertaken to understand the mechanisms underlying the occurrence of drought in these areas.
Performance evaluation of isoproturon-degrading indigenous bacterial isolates in soil microcosm
Creators: name: Giri, Krishna
name: Rai, J. P. N.
name: Pandey, Shailesh
name: Mishra, Gaurav
name: Kumar, Rajesh
name: Suyal, Deep Chandra
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Isoproturon (IPU)-degrading soil bacteria were isolated from herbicide-applied wheat fields. These isolates were identified using cultural, morphological, biochemical and 16S rRNA sequencing methods. 16S rRNA sequences of both the bacterial isolates were compared with NCBI GenBank data base and identified as Bacillus pumilus and Pseudoxanthomonas sp. A soil microcosm study was carried out for 40 days in six different treatments. Experimental results revealed maximum 95.98% IPU degradation in treatment 6 where bacterial consortia were augmented in natural soil, followed by 91.53% in treatment 5 enriched with organic manure as an additional carbon source. However, only 14.03% IPU was degraded in treatment 1 (control) after 40 days. In treatments (2–4), 75.59%, 70.92% and 77.32% IPU degradation was recorded, respectively. IPU degradation in all the treatments varied significantly over the control. 4-Isopropylaniline was detected as IPU degradation by-product in the medium. The study confirmed that B. pumilus and Pseudoxanthomonas sp. performed effectively in soil microcosms and could be employed profitably for field-scale bioremediation experiments.
title: PFC: Enquête Douzens
Creators: name: Équipe De Recherche En Syntaxe Et Sémantique
name: Durand, Jacques
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Français
subject: fra
subject: Viticulture
subject: phonetics
subject: phonology
subject: text_and_corpus_linguistics

description: Annotation du fichier de transcription PRAAT de la conversation libre
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7