cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Non-fatal overdose among people who inject drugs in Tehran, Iran
Creators: name: M Noroozi
name: Higgs, Peter
name: A Bayani
name: B Armoon
name: AN Astaneh
name: LF Moghaddam
name: M Askari
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, The Author(s). Background: With increasing frequencies of non-fatal overdose in people who inject drugs (PWID), it is essential to improve our knowledge about associated risk factors for overdose to inform overdose prevention and assistance programs. The aim of present study was to determine the prevalence of non-fatal overdose and the associated risk factors among PWID in Tehran, Iran. Methods: Snowball sampling was used to collect data from 465 participants in Tehran using a cross-sectional survey. Consenting participants who reported drug injecting in the past month and were able to speak and comprehend Farsi enough to respond to survey questions were interviewed. The endpoint of interest was non-fatal overdose in the previous 6 months, or answering “Yes” to the question: “In the last six months, have you ever overdosed by accident? (at least once)”. We used STATA v. 14 for this analysis. Statistical significance was defined as p < 0.05 for all analyses. Results: Of 465 PWIDs who participated in this study, all were male, and about half had less than a high school education. The prevalence of self-reported non-fatal overdose in the past 6 months was 38% (CI95%: 34, 43%). Our findings indicate that characteristics and behaviors that were associated with an increased risk of experiencing an overdose in the past 6 months were drug use initiation under 22 years (AOR =2.2, P < 0.05), using methamphetamine (AOR =2.8, P
The protective effect of exercise in neurodegenerative diseases: the potential role of extracellular vesicles
Creators: name: OK Fuller
name: M Whitham
name: Mathivanan, Suresh
name: MA Febbraio
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: Physical activity has systemic effects on the body, affecting almost every organ. It is important not only for general health and wellbeing, but also in the prevention of diseases. The mechanisms behind the therapeutic effects of physical activity are not completely understood; however, studies indicate these benefits are not confined to simply managing energy balance and body weight. They also include systemic factors which are released into the circulation during exercise and which appear to underlie the myriad of benefits exercise can elicit. It was shown that along with a number of classical cytokines, active tissues also engage in inter-tissue communication via extracellular vesicles (EVs), specifically exosomes and other small EVs, which are able to deliver biomolecules to cells and alter their metabolism. Thus, EVs may play a role in the acute and systemic adaptations that take place during and after physical activity, and may be therapeutically useful in the treatment of a range of diseases, including metabolic disorders such as type 2 diabetes and obesity; and the focus of this review, neurological disorders such as Alzheimer's disease.
Esports governance: exploring stakeholder dynamics
Creators: name: Q Peng
name: Dickson, Geoff
name: N Scelles
name: J Grix
name: PM Brannagan
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 by the authors. Esports is a rapidly growing industry. However, the unidentifiable governance structure of the industry has contributed to a number of integrity-eroding activities. By exploring esports stakeholder dynamics, this paper answers the question, "Is the esports governance model sustainable?" Data were sourced from documentation, focus groups (N = 3) and semi-structured interviews (N = 6). Thematic analysis was conducted using Nvivo. The findings suggest that (1) the current esports governance framework features some attributes of the "lead organisation-governed network", with the power residing mainly in game publishers; (2) the rising power of other stakeholders in the network seeking to address integrity issues has caused fragmentation of the esports governance framework; (3) esports governance is evolving towards a network administration organisation (NAO) model. Such evolution has a few challenges-most notably, the compliance of game publishers. Given the social impact of the integrity issues, governments should play a main role in facilitating a NAO model.
Impact of Biofield Treatment on Yield, Quality and Control of Nematode in Carrots
Creators: name: Trivedi, Mahendra
Publisher: name: SMN - The ScienceMedia Network
Year: 2016
Subjects: Natural Sciences
Earth sciences

description: This study tested the Null Hypothesis for the effect of biofield treatment when used for control of nematode on carrot crops, Daucus carota , under typical growing conditions in year 2012 at Guadalupe, California, USA. Following biofield treatment, carrot seeds were planted in replicate plots with mechanical seeder and their development was recorded compared to control seed growth from untreated plots and plots treated with the commercial standard nematicide, further Vydate L was applied three times at rates of 1 and 0.5 gal/A, at 1, 18 and 35 days after seeding, respectively. At 70 and 109 days after the first application root galling severity in biofield treated crops was reduced by 54% and 22% respectively as compared to untreated while the Vydate response showed 0% and 25% control, respectively. Plots planted with biofield treated seeds resulted in the greatest number and weight of marketable carrot roots. Total yield and gross return were greatest in biofield treated group producing an approximately 33% increase over the untreated controls and 15% increase over those treated with the commercial standard, Vydate L. Vitamin A (beta carotene) was significantly greater (6512 IU/100 g) in biofield treated carrots compared with both the untreated controls (4941) and the commercial standard (5143). The results concluded that, Biofield treatment caused the numerical improvement in yield along with nematode control in carrots however, caused statistically significant increase in Vitamin A content.
The interaction of the circadian and immune system: desynchrony as a pathological outcome to traumatic brain injury
Creators: name: GR Yamakawa
name: RD Brady
name: M Sun
name: McDonald, Stuart
name: SR Shultz
name: R Mychasiuk
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 The Authors Traumatic brain injury (TBI) is a complex and costly worldwide phenomenon that can lead to many negative health outcomes including disrupted circadian function. There is a bidirectional relationship between the immune system and the circadian system, with mammalian coordination of physiological activities being controlled by the primary circadian pacemaker in the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN receives light information from the external environment and in turn synchronizes rhythms throughout the brain and body. The SCN is capable of endogenous self-sustained oscillatory activity through an intricate clock gene negative feedback loop. Following TBI, the response of the immune system can become prolonged and pathophysiological. This detrimental response not only occurs in the brain, but also within the periphery, where a leaky blood brain barrier can permit further infiltration of immune and inflammatory factors. The prolonged and pathological immune response that follows TBI can have deleterious effects on clock gene cycling and circadian function not only in the SCN, but also in other rhythmic areas throughout the body. This could bring about a state of circadian desynchrony where different rhythmic structures are no longer working together to promote optimal physiological function. There are many parallels between the negative symptomology associated with circadian desynchrony and TBI. This review discusses the significant contributions of an immune-disrupted circadian system on the negative symptomology following TBI. The implications of TBI symptomology as a disorder of circadian desynchrony are discussed.
Aufbau und Eigenschaften von PVD-Hartstoffschichten in den Systemen Cr-Zr-O und Cr-Zr-O-N
Creators: name: Spitz, Stefanie Charlotte
Publisher: name: Karlsruhe
Year: 2016

description: Diese Arbeit beschreibt die Charakterisierung oxidischer PVD-Dünnschichten in den Systemen Cr-Zr-O und Cr-Zr-O-N, die mittels Hochleistungskathodenzerstäubens und unter Anwendung eines experimentellen materialkombinatorischen Ansatzes abgeschieden wurden. In Abhängigkeit der Zusammensetzung und der variierten Abscheideparameter treten hauptsächlich vier Phasen auf: eine Cr2O3-basierte Phase sowie drei ZrO2-basierte Phasen.
MESIOBUCCAL ROOT VOLUME AND THE PRESENCE OF THE SECOND
Creators: name: André Luis Alves BORGES
name: Romulo de Oliveira SALES-JUNIOR
name: Hébel Cavalcanti GALVÃO
name: João Eduardo GOMES-FILHO
name: Antonione Santos Bezerra PINTO
name: Carlos Alberto Monteiro FALCÃO
name: Maria Ângela Arêa Leão FERRAZ
Publisher: name: Zenodo
Year: 2025
Subjects: Root canal
Computed tomography
Volume

description: ABSTRACT

 

Identifying anatomical variations in the mesiobuccal root of maxillary first molars is essential for endodontic success. This study evaluated the presence of a second canal in this root and its correlation with root volume in a Brazilian subpopulation. A total of 142 CT scans of maxillae were analysed for volumetric assessment and canal identification. Root volume was calculated using InVersalius, and the second canal was identified with OnDemand3D Dental.Ink. Pearson’s chi-squared test and the Mann-Whitney test (p < 0.05) were applied using R2 Commander. A total of 284 maxillary first molars were analysed, with a mean volume of 98.888 mm³ for tooth 16 and 94.093 mm³ for tooth 26. The second mesiobuccal canal was present in 77.11% of the teeth. No statistical association was found between its presence and root volume or between the mean volumes of teeth 16 and 26. While vestibular root volumes showed no significant differences, the mesiobuccal root volume was significantly higher in males. In conclusion, in this Brazilian subpopulation, there was no correlation between the presence of a second mesiobuccal canal and root volume variations in maxillary first molars.
title: Right to Repair: Impact on Competitiveness of Agricultural Machinery Firms
Creators: name: Peters, Caroline
name: Taylor, Brennan
Publisher: name: United States International Trade Commission
publisherIdentifier: https://ror.org/05hsggr76
publisherIdentifierScheme: ROR
Year: 2023

description: The right to repair (RTR) has become a prominent issue facing the agricultural machinery sector globally,
with farmers concerned about their ability to repair newer equipment without the assistance of dealerships
or original equipment manufacturers (OEMs), who oppose revealing their source code due to concerns of
patent protection, emission compliance, and safety. This EBOT discusses the perspectives of various
stakeholders on RTR, the competitiveness issues that RTR raises for equipment manufacturers, and the
actions government and industry have taken in response to certain aspects of farmers’ RTR concerns.
On the horns of a dilemma: experts as communicators for property‐level flood risk adaptation measures
Creators: name: Davids, Peter R.
name: Priest, Sally
name: Hartmann, Thomas
Publisher: name: TU Dortmund
Year: 2023
Subjects: subject: Belgium
subject: cultural theory
subject: flood risk communication
subject: flood risk experts
subject: homeowners
subject: property-level risk adaption
subject: 710

description: This paper investigates the role of flood risk experts in supporting homeowners to implement property-level flood risk adaption (PLFRA). Homeowners can reduce their flood risks by implementing PLFRA. However, oftentimes they need advice on what sort of and how to implement PLFRA. This means that tailored experts advice is necessary to inform homeowners on such measures. But experience shows that mere information is often insufficient to motivate homeowners to realise measures. This contribution explores the reasons for the ineffectiveness of expert advice by investigating how expert advice responds to homeowners' rationalities. Based on a case study from Flanders, Belgium, this paper reveals how the relation between experts and homeowners differs related to different rationalities of homeowners. The paper uses Cultural Theory to discuss strategies on how experts, providing advice on property-level risk adaption, could move beyond engineering skills by also using risk communication skills in order to involve homeowners in flood risk governance.
description: Journal of flood risk management;16(2)
Nutritional profile of rodent diets impacts experimental reproducibility in microbiome preclinical research
Creators: name: Tuck, Caroline
name: G De Palma
name: K Takami
name: B Brant
name: A Caminero
name: DE Reed
name: JG Muir
name: PR Gibson
name: A Winterborn
name: EF Verdu
name: P Bercik
name: S Vanner
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, The Author(s). The lack of reproducibility of animal experimental results between laboratories, particularly in studies investigating the microbiota, has raised concern among the scientific community. Factors such as environment, stress and sex have been identified as contributors, whereas dietary composition has received less attention. This study firstly evaluated the use of commercially available rodent diets across research institutions, with 28 different diets reported by 45 survey respondents. Secondly, highly variable ingredient, FODMAP (Fermentable Oligo-, Di-, Mono-saccharides And Polyols) and gluten content was found between different commercially available rodent diets. Finally, 40 mice were randomized to four groups, each receiving a different commercially available rodent diet, and the dietary impact on cecal microbiota, short- and branched-chain fatty acid profiles was evaluated. The gut microbiota composition differed significantly between diets and sexes, with significantly different clusters in β-diversity. Total BCFA were highest (p = 0.01) and SCFA were lowest (p = 0.03) in mice fed a diet lower in FODMAPs and gluten. These results suggest that nutritional composition of commercially available rodent diets impact gut microbiota profiles and fermentation patterns, with major implications for the reproducibility of results across laboratories. However, further studies are required to elucidate the specific dietary factors driving these changes.
Ultra-compact Binary Neural Networks for Human Activity Recognition on RISC-V Processors
Creators: name: Daghero, Francesco
name: Xie, Chen
name: Pagliari, Daniele Jahier
name: Burrello, Alessio
name: Castellano, Marco
name: Gandolfi, Luca
name: Calimera, Andrea
name: Macii, Enrico
name: Poncino, Massimo
Publisher: name: arXiv
Year: 2022
Subjects: subject: Machine Learning (cs.LG)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Human Activity Recognition (HAR) is a relevant inference task in many mobile applications. State-of-the-art HAR at the edge is typically achieved with lightweight machine learning models such as decision trees and Random Forests (RFs), whereas deep learning is less common due to its high computational complexity. In this work, we propose a novel implementation of HAR based on deep neural networks, and precisely on Binary Neural Networks (BNNs), targeting low-power general purpose processors with a RISC-V instruction set. BNNs yield very small memory footprints and low inference complexity, thanks to the replacement of arithmetic operations with bit-wise ones. However, existing BNN implementations on general purpose processors impose constraints tailored to complex computer vision tasks, which result in over-parametrized models for simpler problems like HAR. Therefore, we also introduce a new BNN inference library, which targets ultra-compact models explicitly. With experiments on a single-core RISC-V processor, we show that BNNs trained on two HAR datasets obtain higher classification accuracy compared to a state-of-the-art baseline based on RFs. Furthermore, our BNN reaches the same accuracy of a RF with either less memory (up to 91%) or more energy-efficiency (up to 70%), depending on the complexity of the features extracted by the RF.
description: Published in: 2021 18th ACM International Conference on Computing Frontiers (CF)
Supplementary document for Optimization of highly inclined Illumination for diffraction-limited and super-resolution microscopy - 6462895.pdf
Creators: name: Gardini, Lucia
name: Vignolini, Tiziano
name: Curcio, Valentina
name: Pavone, Francesco
name: Capitanio, Marco
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Photonics, Optoelectronics and Optical Communications

description: revised supplemental document
MONG: An extension to galaxy clusters
Creators: name: Rebecca, Louise
name: Kenath, Arun
name: Sivaram, C
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The presence of dark matter, though well established by indirect evidence, is yet to be observed directly. Various dark matter detection experiments running for several years have yielded no positive results. In view of these negative results, we had earlier proposed alternate models by postulating a minimum gravitational field strength (minimum curvature) and a minimum acceleration. These postulates led to the modified Newtonian dynamics and modified Newtonian gravity (MONG). The observed flat rotation curves of galaxies were also accounted for through these postulates. Here we extend these postulates to galaxy clusters and model the dynamical velocity-distance curve for a typical cluster such as the Virgo cluster. The radial velocities of galaxies in the Virgo cluster are also obtained through this model. Observations show an inconsistency in the Hubble flow at a mean cluster distance of 17 Mpc, which is expected in regions of high matter density. This decrease in velocity is predicted by our model of modified gravity (MONG). The radial velocity versus distance relation for galaxies in the Virgo cluster obtained using MONG is in agreement with observations.
description: 9 pages, 2 figures, 21 equations
Atypical manifestation of Pulmonary sarcoidosis simulating metastatic disease.
Creators: name: Mewazy, Fahad
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Lung
subject: CT
subject: Conventional radiography
subject: Diagnostic procedure
subject: Imaging sequences
subject: Inflammation

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 20 years
description: Clinical History: A 20-years-old gentleman complaining of cough and fever for many weeks. No weight loss. Final Diagnosis: Sarcoidosis proven by biopsy.
Differential production of phenolics, lipids, carbohydrates and proteins in stressed and unstressed aquatic plants, azolla filiculoides and azolla pinnata
Creators: name: TL Nham Tran
name: AF Miranda
name: Shamila Abeynayake
name: A Mouradov
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The metabolic plasticity of shikimate and phenylpropanoid pathways redirects carbon flow to different sink products in order to protect sessile plants from environmental stresses. This study assessed the biochemical responses of two Azolla species, A. filiculoides and A. pinnata, to the combined effects of environmental and nutritional stresses experienced while growing outdoors under Australian summer conditions. These stresses triggered a more than 2-fold increase in the production of total phenols and their representatives, anthocyanins (up to 18-fold), flavonoids (up to 4.7-fold), and condensed tannins (up to 2.7-fold), which led to intense red coloration of the leaves. These changes were also associated with an increase in the concentration of carbohydrates and a decrease in concentrations of lipids and total proteins. Changes in lipid biosynthesis did not cause significant changes in concentrations of palmitoleic acid (C16:0), linolenic acid (C18:3), and linoleic acid (C18:2), the fatty acid signatures of Azolla species. However, a reduction in protein production triggered changes in biosynthesis of alanine, arginine, leucine, tyrosine, threonine, valine, and methionine amino acids. Stress-triggered changes in key nutritional components, phenolics, lipids, proteins, and carbohydrates could have a significant impact on the nutritional value of both Azolla species, which are widely used as a sustainable food supplement for livestock, poultry, and fish industries.
Effect of external energy on the atomic, crystalline, and powder characteristics of antimony and bismuth powders
Creators: name: Trivedi, Mahendra
Publisher: name: SMN - The ScienceMedia Network
Year: 2016
Subjects: Natural Sciences
Chemistry

description: Next to atoms and molecules the powders are the smallest state of matter available in high purities and large quantities. The effect of any external energy on the shape, morphology and structure can thus be studied with relative ease. The present investigation deals with the effect of a non-contact external energy on the powders of antimony and bismuth. The characteristics of powders treated by external energy are compared with the as received powders (control). The average particle sizes, d50 and d99, the sizes below which 99% of the particles are present showed significant increase and decrease indicating that the energy had caused deformation and fracture as if the powders have been subjected to high energy milling.

To be able to understand the reasons for these changes the powders are characterized by techniques such as X-ray diffraction (XRD), surface area determination (BET), thermal analytical techniques such as DTA–DTG, DSC–TGA and SDTA and scanning electron microscopy (SEM).

The treated powder samples exhibited remarkable changes in the powder characteristics at all structural levels starting from polycrystalline particles, through single crystal to atoms. The external energy had changed the lattice parameters of the unit cell which in turn changed the crystallite size and density. The lattice parameters are then used to compute the weight and effective nuclear charge of the atom which showed significant variation. It is speculated that the external energy is acting on the nucleus through some reversible weak interaction of larger cross section causing changes in the proton to neutron ratios. Thus the effect is felt by all the atoms, and hence the unit cell, single crystal grain and grain boundaries. The stresses generated in turn may have caused deformation or fracture of the weak interfaces such as the crystallite and grain boundaries.
МОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЕ СЕЛЕЗЁНКА ПРИ ВОЗДЕЙСТВИИ ХИМИОТЕРАПИЯ
Creators: name: Ходжиева, Нозима
Publisher: name: Zenodo
Year: 2024

description: Глобальной проблемой последних десятилетий, как и прежде, остается высокая распространенность случаев заболеваемости и смертности от онкопатологии. Согласно современным сведениям от международного агентства по изучению рака за 2018 год зарегистрировано максимальное число впервые выявленных случаев заболеваемости злокачественными новообразованиями за всю историю существования [1]. По предварительному прогнозу к 2040 году ожидается увеличение этой цифры до 29,5 млн. человек. А количество смертей от злокачественных опухолей возрастет с 9,5 млн. до 16,3 млн. случаев [2]
Automatic question generation based on sentence structure analysis using machine learning approach
Creators: name: Blšták, Miroslav
name: Rozinajová, Viera
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Automatic question generation is one of the most challenging tasks of Natural Language Processing. It requires "bidirectional" language processing: firstly, the system has to understand the input text (Natural Language Understanding) and it then has to generate questions also in the form of text (Natural Language Generation). In this article, we introduce our framework for generating the factual questions from unstructured text in the English language. It uses a combination of traditional linguistic approaches based on sentence patterns with several machine learning methods. We firstly obtain lexical, syntactic and semantic information from an input text and we then construct a hierarchical set of patterns for each sentence. The set of features is extracted from the patterns and it is then used for automated learning of new transformation rules. Our learning process is totally data-driven because the transformation rules are obtained from a set of initial sentence-question pairs. The advantages of this approach lie in a simple expansion of new transformation rules which allows us to generate various types of questions and also in the continuous improvement of the system by reinforcement learning. The framework also includes a question evaluation module which estimates the quality of generated questions. It serves as a filter for selecting the best questions and eliminating incorrect ones or duplicates. We have performed several experiments to evaluate the correctness of generated questions and we have also compared our system with several state-of-the-art systems. Our results indicate that the quality of generated questions outperforms the state-of-the-art systems and our questions are also comparable to questions created by humans. We have also created and published an interface with all created datasets and evaluated questions, so it is possible to follow up on our work.
FIRST RECORD OF THE SYNECHODONTIFORM SHARK  SPHENODUS (NEOSELACHII, ORTHACODONTIDAE) FROM THE  DANIAN OF EASTERN NORTH AMERICA
Creators: name: Callahan, Wayne R
name: Schein, Jason P.
name: Parris, David C
name: Shankle, William
Publisher: name: Zenodo
Year: 2014
Subjects: Paleontology
Shark Teeth
Sphenodus

description: The rare, cold-water synechodontiform shark Sphenodus is here reported from the Hornerstown Formation (Danian) of Gloucester County, New Jersey. A well-preserved, upper-right lateral tooth was recovered from the Inversand Company glauconite quarry in June 2011. Based on size, tooth crown and root morphology, and age, the tooth (NJSM GP23223) is assigned to Sphenodus lundgreni (Davis, 1890) and represents the first record of this taxon from the Danian of eastern North America
The perception and knowledge of financial risk of the Portuguese
Creators: name: F Tavares
name: E Santos
name: V Tavares
name: Ratten, Vanessa
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020 by the authors. This study will help academics, researchers, and professionals to better understand how the Portuguese population perceives financial risk. Thus, the main objective of this study is to analyse and compare the perception and knowledge of financial risk by the Portuguese. The methodology used is quantitative, and the measurement instrument consists of three parts: financial risk perception, financial risk knowledge and sociodemographic characterization of the participants. The sample is composed of 830 Portuguese individuals, over 18 years old. The results demonstrate that financial risk perception is a one-dimensional measurement and that there are low levels of both perception and knowledge of financial risk. It can also be concluded that the Portuguese individuals have a higher level of financial risk perception, when compared to financial risk knowledge, and it is men who have higher levels of perception and knowledge of financial risk. Thus, this study contributes to the literature on financial risk by presenting empirical evidence and relevant conclusions, and it is therefore expected that it will help to improve the perception and knowledge of the financial risk of the Portuguese and, consequently, their financial decisions and financial well-being. Therefore, the study fills a gap, since there are no studies in Portugal that assess the perception and knowledge of financial risk of the Portuguese.
Personalized Monitoring Model for Electrocardiogram Signals: Diagnostic Accuracy Study
Creators: name: Kotorov, Rado
name: Chi, Lianhua
name: Shen, Min
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 37
subject: Earth sciences
classificationCode: 3704
subject: Geoinformatics

description: Background: Due to the COVID-19 pandemic, the demand for remote electrocardiogram (ECG) monitoring has increased drastically in an attempt to prevent the spread of the virus and keep vulnerable individuals with less severe cases out of hospitals. Enabling clinicians to set up remote patient ECG monitoring easily and determining how to classify the ECG signals accurately so relevant alerts are sent in a timely fashion is an urgent problem to be addressed for remote patient monitoring (RPM) to be adopted widely. Hence, a new technique is required to enable routine and widespread use of RPM, as is needed due to COVID-19. Objective: The primary aim of this research is to create a robust and easy-to-use solution for personalized ECG monitoring in real-world settings that is precise, easily configurable, and understandable by clinicians. Methods: In this paper, we propose a Personalized Monitoring Model (PMM) for ECG data based on motif discovery. Motif discovery finds meaningful or frequently recurring patterns in patient ECG readings. The main strategy is to use motif discovery to extract a small sample of personalized motifs for each individual patient and then use these motifs to predict abnormalities in real-time readings of that patient using an artificial logical network configured by a physician. Results: Our approach was tested on 30 minutes of ECG readings from 32 patients. The average diagnostic accuracy of the PMM was always above 90% and reached 100% for some parameters, compared to 80% accuracy for the Generalized Monitoring Models (GMM). Regardless of parameter settings, PMM training models were generated within 3-4 minutes, compared to 1 hour (or longer, with increasing amounts of training data) for the GMM. Conclusions: Our proposed PMM almost eliminates many of the training and small sample issues associated with GMMs. It also addresses accuracy and computational cost issues of the GMM, caused by the uniqueness of heartbeats and training issues. In addition, it addresses the fact that doctors and nurses typically do not have data science training and the skills needed to configure, understand, and even trust existing black box machine learning models.
Spin dynamics and continuum spectra of the honeycomb J1-J2 antiferromagnetic Heisenberg model
Creators: name: Gu, Cheng
name: Yu, Shun-Li
name: Li, Jian-Xin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We employ the spin cluster perturbation theory to investigate the dynamical properties of the antiferromagnetic $J_{1}$-$J_{2}$ Heisenberg model on the honeycomb lattice. We obtain the excitation spectra for all possible phases in the phase diagram, including the Néel phase, plaquette valence-bond-solid phase, dimer valence-bond-solid phase and stripe antiferromagnetic phase. In the Néel phase, besides the obvious renormalization of the magnon dispersion, we find that the spectrum exhibits a dome-shaped broad continuum around the second Brillouin zone (BZ) and the additional strong continuum close to the corner of the BZ. In the valence-bond-solid phases, the spectra are dominated by a strong broad continuum all the way down to below $J_1$ coexisting with the lowest-energy triplon modes characterizing the plaquette and dimer phases. We ascribe this strong broad continuum and the additional continuum close to the BZ corner in the Néel phase to the contributions of fractionalized spinon excitations. In the stripe phase, a clear difference from the linear spin wave approximation is that the spectrum is gapped at the $M$ point while that obtained by the latter is gapless due to the strong quantum fluctuations. We point out that the features observed in the Néel phase are consistent with the recent neutron scattering experiments on YbCl$_{3}$ and YbBr$_{3}$.
description: 8 pages, 6 figures
Relationships between UBE3A and SNORD116 expression and features of autism in chromosome 15 imprinting disorders
Creators: name: Baker, Emma
name: MG Butler
name: SN Hartin
name: L Ling
name: M Bui
name: D Francis
name: C Rogers
name: MJ Field
name: J Slee
name: D Gamage
name: DJ Amor
name: DE Godler
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, The Author(s). Chromosome 15 (C15) imprinting disorders including Prader–Willi (PWS), Angelman (AS) and chromosome 15 duplication (Dup15q) syndromes are severe neurodevelopmental disorders caused by abnormal expression of genes from the 15q11–q13 region, associated with abnormal DNA methylation and/or copy number changes. This study compared changes in mRNA levels of UBE3A and SNORD116 located within the 15q11–q13 region between these disorders and their subtypes and related these to the clinical phenotypes. The study cohort included 58 participants affected with a C15 imprinting disorder (PWS = 27, AS = 21, Dup15q = 10) and 20 typically developing controls. Semi-quantitative analysis of mRNA from peripheral blood mononuclear cells (PBMCs) was performed using reverse transcription droplet digital polymerase chain reaction (PCR) for UBE3A and SNORD116 normalised to a panel of internal control genes determined using the geNorm approach. Participants completed an intellectual/developmental functioning assessment and the Autism Diagnostic Observation Schedule-2nd Edition. The Dup15q group was the only condition with significantly increased UBE3A mRNA levels when compared to the control group (p < 0.001). Both the AS and Dup15q groups also had significantly elevated SNORD116 mRNA levels compared to controls (AS: p < 0.0001; Dup15q: p = 0.002). Both UBE3A and SNORD116 mRNA levels were positively correlated with all developmental functioning scores in the deletion AS group (p < 0.001), and autism features (p < 0.001) in the non-deletion PWS group. The findings suggest presence of novel interactions between expression of UBE3A and SNORD116 in PBMCs and brain specific processes underlying motor and language impairments and autism features in these disorders.
North Atlantic right whale calving area surveys : 2014/2015 results
Creators: name: Zoodsma, Barbara J.
name: Howe, Kesley
name: White, Melanie
name: Jakush, Jen
name: George, Clay
name: Gowan, Tim
name: Hamilton, Philip
name: Jackson, Katie
name: Pitchford, Tom
name: Taylor, Cynthia
name: Ward, Leslie
Publisher: name: U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Southeast Regional Office.
Year: 2016
Subjects: subject: Right whales--Detection--Atlantic Coast (South Atlantic States)

description: Aerial surveys are flown December 1 through March 31, annually, in the Southeast United States to detect North Atlantic right whales in their primary calving area. The purpose of the aerial surveys is to contribute to (in prioritized order): Population monitoring via detection and identification of individual right whales including cow/calf pairs occurring in the Southeast United States each year; Monitoring trends in human-related serious injuries and mortality; Vessel-strike reduction Given these prioritized objectives, we focused aerial surveys in areas where we expected the highest number of right whale detections.
Prescribers or multidisciplinarians? An evaluation of brief education for general practitioners on chronic pain management
Creators: name: Holliday, Simon Mark
name: Hayes, Chris
name: Jones, Lester
name: Gordon, Jill
name: Fraser, Catherine
name: Newman Harris
name: Nicholas, Michael
name: Holder, Carl
name: Oldmeadow, Christopher
name: Magin, Parker
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Purpose Active pain self-management (PSM) for patients with chronic pain is assumed to require multidisciplinary care, leaving prescribing analgesics the most accessible option for general practitioners (GPs). We sought to upskill GPs in multimodalPSM with a harm minimisation approach for any opioid prescribing. Design and Methodology Having developed an educational training resource, a multidisciplinary team delivered the program to attendees at a GP conference in 2017. The educational package comprised pre-readings, a 6-hour interactive, skills-based workshop, and post-workshop resources. The single-group intervention was evaluated with an original and unvalidated pre/post-test (three months) survey of four domains: knowledge; attitudes; utilisation of strategies involving PSM and opioid harm minimization. Paired t-tests were conducted on each domain score and overall, with effect sizes assessed with Cohen’s d. A sensitivity analysis was performed on the data lacking a post-test survey response. Post-survey scores were imputed via chained regression equations, then paired t-tests analyses were conducted on imputed datasets using Rubin's method to pool estimates. FindingsOf 99 participants, 33 returned both surveys for primary analysis. These were combined in the sensitivity analysis with 60 unpaired surveys. Internal consistency was modest (Cronbach’s alpha 0.736). Primary analysis demonstrated significant self-reported improvements in each educational domain with overall score increasing 10.54 points out of 130 (p<0.001 Cohen’s d 1.11). Improvements were similar in a sensitivity analysis. Discussion, Limitations and Conclusions This study found that a brief GP educational package may be a viable intervention for facilitating PSM and promoting safer prescribing strategies. Outcomes at three months, from this unvalidated survey instrument, suggest improvements in knowledge, attitudes and self-reported facilitation of PSM and opioid prescribing. As this study did not measure clinician behaviour or patient outcomes objectively, further educational research is indicated to confirm these findings and identify how best to deliver chronic pain management training.
An Investigation into Spiritual Education in Jewish Orthodox Schools
Creators: name: J. Pearlman, Yehuda
Publisher: name: University of Leicester
Year: 2025

description: This project seeks to gain an understanding of what spirituality means from a Jewish perspective and how it can be incorporated into the educational provision of Jewish schools in the UK. The literature review explores the relationship between spirituality and religion in general. Two approaches to spirituality are identified, one which promotes the experiential and the other which encourages critical realism. It is suggested that relational consciousness could be used as an educational model to harmonise the two approaches. Sources within Jewish literature are then explored, uncovering similar approaches and concluding with the description of a Jewish model for spiritual learning. The merit of a qualitative study is justified as best suited to investigate the perceptions and attitudes of Jewish studies teachers towards Jewish spiritual education. Using semi-structured interviews, a purposive sample of nine Jewish studies primary school teachers are asked what spirituality means to them, how they attempt to incorporate it into their religious studies lessons and what the impact of teaching spiritually on their students is. The responses are analysed using the inductive approach of IPA to reveal four overarching themes. Three themes frame spiritual education as the development of relationships within pupils, between themselves and others, and themselves and God. The fourth category focuses on the pedagogy deployed by the teachers and the challenges they face in delivering spiritual education. The research highlights two approaches to spiritual education, with one group of teachers preferring an extrinsic approach, imbuing their lessons with meaning and purpose. The other group view spirituality as an intrinsic quality that when nurtured, brings to the fore creativity and individuality. The centrality of a philosophy of God’s immanence as a foundation for spiritual education is emphasised and a model which promotes dialogue, relationships and community is presented as one that could be implemented to deliver Jewish spiritual education.
An extreme-phenotype genome‐wide association study identifies candidate cannabinoid pathway genes in Cannabis
Creators: name: Welling, Matthew
name: L Liu
name: T Kretzschmar
name: R Mauleon
name: O Ansari
name: GJ King
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, The Author(s). Cannabis produces a class of isoprenylated resorcinyl polyketides known as cannabinoids, a subset of which are medically important and exclusive to this plant. The cannabinoid alkyl group is a critical structural feature that governs therapeutic activity. Genetic enhancement of the alkyl side-chain could lead to the development of novel chemical phenotypes (chemotypes) for pharmaceutical end-use. However, the genetic determinants underlying in planta variation of cannabinoid alkyl side-chain length remain uncharacterised. Using a diversity panel derived from the Ecofibre Cannabis germplasm collection, an extreme-phenotype genome-wide association study (XP-GWAS) was used to enrich for alkyl cannabinoid polymorphic regions. Resequencing of chemotypically extreme pools revealed a known cannabinoid synthesis pathway locus as well as a series of chemotype-associated genomic regions. One of these regions contained a candidate gene encoding a β-keto acyl carrier protein (ACP) reductase (BKR) putatively associated with polyketide fatty acid starter unit synthesis and alkyl side-chain length. Association analysis revealed twenty-two polymorphic variants spanning the length of this gene, including two nonsynonymous substitutions. The success of this first reported application of XP-GWAS for an obligate outcrossing and highly heterozygote plant genus suggests that this approach may have generic application for other plant species.
Open Library Badge. Ein Anreizsystem Für Mehr Offenheit In Bibliotheken
Creators: name: Heller, Lambert
name: Langhanke, Gerald
name: Lohmeier, Felix
name: Katzer, Anton
name: Stöhr, Matti
name: Voigt, Michaela
Publisher: name: Zenodo
Year: 2016

description: Open Library Badge. Ein Anreizsystem für mehr Offenheit in Bibliotheken
Examining quality of life in an Australian cohort of people with epilepsy over six years — Understanding the role of stigma and mood
Creators: name: H Coleman
name: Peterson, Chris
name: C Walker
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © 2020 Elsevier Inc.
Aim: Research examining quality of life (QoL) among people living with epilepsy (PWE) consistently highlights the detrimental impact of stigma, anxiety, and depression, as well as the dynamic and changing nature of QoL over time. This paper represents the first panel study of the Australian Epilepsy Longitudinal Survey (AELS), examining factors that influence the QoL of PWE over a six-year interval, particularly focusing on experiences of stigma, depression, and anxiety. Methods: Ninety-two adults participated in both Wave 2 (T1; 2010) and Wave 4 (T2; 2016/17) of the AELS. Average age at T2 was 53.4 years [standard deviation (SD) = 15.3; range: 22–82; 55% female]. Over the study interval, there was a shift towards more younger participants moving out of high school and older participants moving into retirement. We explored the impact of (i) experiences of stigma, (ii) mood, and (iii) sociodemographic factors on QoL at both T1 and T2 via the use of correlation analyses. Hierarchical regression was used to determine the strongest predictors of QoL at T2. Results: Occurrence of recent seizures, stigma, anxiety, and depression measured at T1 were all significantly correlated with total QoL at both T1 and T2. Sociodemographic factors including years of education, and weekly income before tax were not significantly correlated with QoL at either T1 or T2. QoL and depression at T1 were identified as the strongest predictors of QoL at T2 (six years later). Discussion: The current study supports previous research highlighting the importance of psychological factors in understating QoL in PWE, particularly stigma, anxiety, and depression. In particular, it highlights the impact of depression on QoL over a 6-year interval, providing evident for the long-term nature of this relationship.
Supplementary document for Optimization of highly inclined Illumination for diffraction-limited and super-resolution microscopy - 6462895.pdf
Creators: name: Gardini, Lucia
name: Vignolini, Tiziano
name: Curcio, Valentina
name: Pavone, Francesco
name: Capitanio, Marco
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Photonics, Optoelectronics and Optical Communications

description: revised supplemental document
Fairness of Exposure in Light of Incomplete Exposure Estimation
Creators: name: Heuss, Maria
name: Sarvi, Fatemeh
name: de Rijke, Maarten
Publisher: name: arXiv
Year: 2022
Subjects: subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Fairness of exposure is a commonly used notion of fairness for ranking systems. It is based on the idea that all items or item groups should get exposure proportional to the merit of the item or the collective merit of the items in the group. Often, stochastic ranking policies are used to ensure fairness of exposure. Previous work unrealistically assumes that we can reliably estimate the expected exposure for all items in each ranking produced by the stochastic policy. In this work, we discuss how to approach fairness of exposure in cases where the policy contains rankings of which, due to inter-item dependencies, we cannot reliably estimate the exposure distribution. In such cases, we cannot determine whether the policy can be considered fair. Our contributions in this paper are twofold. First, we define a method called FELIX for finding stochastic policies that avoid showing rankings with unknown exposure distribution to the user without having to compromise user utility or item fairness. Second, we extend the study of fairness of exposure to the top-k setting and also assess FELIX in this setting. We find that FELIX can significantly reduce the number of rankings with unknown exposure distribution without a drop in user utility or fairness compared to existing fair ranking methods, both for full-length and top-k rankings. This is an important first step in developing fair ranking methods for cases where we have incomplete knowledge about the user's behaviour.
description: 12 pages, 2 figures, will be published at SIGIR 2022
Open-Access-Repository, Forschungsdatenarchiv, Hochschulbibliographie: Wie „3 In 1“ Gelingen Kann
Creators: name: Hirschmann, Barbara
Publisher: name: Zenodo
Year: 2016

description: Open-Access-Repository, Forschungsdatenarchiv, Hochschulbibliographie: Wie „3 in 1“ gelingen kann
La Chiesa della comunità arbëreshë e la Chiesa di rito greco-cattolica in Albania: una sola Chiesa
Creators: name: Cimbalo, Giovanni
Publisher: name: Università degli Studi di Milano
Year: 2016
Subjects: Diritti delle religioni

description: Il contributo, non sottoposto a valutazione, riproduce l’Intervento alla Konferencën ndërkombëtare albanologjike “Urat kulturore mes himarës dhe disporës arbërore në shek. XVI-XVIII” – Conference “Cultural bridges between Himara and the Arberesh diaspora during the 16th and 18th centuries”, held in Vlorë, since 10 to 11 November 2015.
SOMMARIO: 1. Il cristianesimo in Albania tra oriente e occidente - 2. I cattolici di rito greco in Italia e il ruolo degli arbëreshë - 3. I cattolici di rito greco bizantino nel sud dell’Albania come testa di ponte verso i Balcani - 4. La persecuzione contro la Chiesa cattolica in Albania e la confisca dei beni ecclesiastici.
description: Stato, Chiese e pluralismo confessionale, 2016: 3 ottobre