cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Exposure to low intensity ultrasound removes paclitaxel cytotoxicity in breast and ovarian cancer cells
Creators: name: Amaya, Celina
name: Luo, Shihua
name: Baigorri, Julio
name: Baucells, Rogelio
name: Smith, Elizabeth R.
name: Xu, Xiang-Xi
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Computational Biology

description: Additional file 1: Supplementary Figure 1. Disruption of microtubule cytoskeleton in OVCAR3 ovarian cancer cells. (A) OVCAR3 ovarian cancer cells on tissue culture dish were exposed to ultrasound (+ US, 40 KHz, 3 W/cm2) for 5 min. The cells were then were fixed and processed for immunostaining for alpha-tubulin and Lamin A/C. (B) OVCAR3 cells on tissue culture dish were exposed to ultrasound (+ US, 40 KHz, 1 W/cm2) for 5 min and then were fixed and processed for analyses by immunofluorescence microscopy for alpha tubulins and Lamin B. Supplementary Figure 2. Disruption of fluorescence labeled Taxol bound microtubule cytoskeleton in cancer cells by ultrasound. Breast (MCF-7) and ovarian (OVCAR3, OVCAR8) cancer cells were added with fluorescence labeled Taxol analog (488-PTX) (1 nM) for 60 min. The cells on tissue culture dish were exposed to ultrasound (+ US, 40 KHz, 1.0 W/cm2) for 5 min. Representative 488-PTX images were taken before (control) and after exposure to ultrasound. Supplementary Figure 3. Disruption and progressively elimination of fluorescence labeled Taxol bound microtubule cytoskeleton in ovarian cancer cells by ultrasound. OVCAR3 ovarian cancer cells were added with fluorescence labeled Taxol analog (488-PTX) (1 nM) for 60 min. The cells on tissue culture dish were exposed to ultrasound (+ US, 40 KHz, 1.0 W/cm2) for 5 min. Representative 488-PTX images were taken before (control) and after exposure to ultrasound for 0, 10, 20, and 30 min.
Gyula Török, Die Bewohner von Halimba im 10. und 11. Jahrhundert
Creators: name: Hinz, Hermann
Publisher: name: Bonner Jahrbücher
Year: 2020

description: Rezension zu: Gyula Török, Die Bewohner von Halimba im 10. und 11. Jahrhundert. Arch. Hungarica, Series Nova XXXIX. Budapest 1962. 169 Seiten, 110 Tafeln, 36 Abbildungen und 4 Beilagen.
description: Bonner Jahrbücher, Bd. 162 (1962): Bonner Jahrbücher
CoActuamos por la Salud Mental: un proyecto participativo con y para la comunidad de la salud mental
Creators: name: Campos, Inma
name: Fernández, Alba
name: Muntadas, Alba
name: Figueras, Amanda
name: Mateo, Vicenç
name: Mateu, Assumpta
name: Torné, Salut
name: Cigarini, Anna
name: Peter, Franziska
name: Bonhoure, Isabelle
name: González, Itziar
name: Perelló, Josep
Publisher: name: Zenodo
Year: 2021
Subjects: Citizen Social Science
Mental Health
Social suport Networks
Chatbot

description: Las personas que nos rodean son claves para nuestro bienestar emocional. Este entorno afectivo y social, denominado redes de apoyo social, nos conecta entre todas y es especialmente importante para nuestra salud mental. El objetivo global del proyecto “CoActuamos por la Salud Mental” es tener un conocimiento detallado del funcionamiento de las redes de apoyo social en salud mental, para así poder proponer acciones para mejorarlas.Para lograr este objetivo, nos situamos en el marco de la ciencia ciudadana social, que involucra a la ciudada-nía que comparte una preocupación social como personas co-investigadoras y coactores de la investigación. En septiembre de 2020, el grupo OpenSystems de la Universitat de Barcelona y la Federació Salut Mental Catalunya lanzaron un llamamiento abierto a personas con experiencia propia en salud mental, incluyen-do familiares, para participar como personas co-investigadoras. Después de dos reuniones informativas, se constituyó un grupo de 32 personas co-investigadoras que se están implicando en todas las etapas de la investigación, incluyendo esta presentación. El “equipo de investigación” (denominado así a partir de este momento) está pues constituido por las personas co-investigadoras, los investigadores del ámbito de la cien-cia ciudadana (OS-grupo OpenSystems) y los representantes del movimiento asociativo de las personas con experiencia propia en salud mental (FSMC-Federació Salut Mental Catalunya). Todos los grupos implicados en la investigación están llevando a cabo la presentación conjuntamente.Para obtener información científica relevante sobre las redes de apoyo social en salud mental, el equipo de in-vestigación co-creó un chatbot en Telegram que permite a todas las personas mayores de edad participar en esta investigación a gran escala, desde cualquier parte del mundo y desde cualquier perspectiva individual. Todos los contenidos están disponibles en Catalán, Castellano, Inglés y Alemán.
Probing Quartic Neutral Gauge Boson Couplings using diffractive photon fusion at the LHC
Creators: name: Gupta, Rick S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A complete list of operators contributing at the lowest order to Quartic Neutral Gauge Boson Couplings involving photons and Z-bosons, is presented. We show that, for the couplings we consider, the lowest order contribution is from dimension 8 operators in the case when a light Higgs is present and from dimension 6 operators in the higgsless case where electroweak symmetry is non-linearly realized. We also show that these operators are generated by exchange of the Kaluza-Klein partners of the graviton in extra-dimensional models. We then explore the possibility of probing these couplings in the diffractive photon fusion processes pp(γγ\to γγ)pp and pp(γγ\to ZZ)pp at the 14 TeV LHC. We find that the γγγγ-coupling can be probed most sensitively and values as small as 1/(1.8 TeV)^{4} can be measured. For the γγZZ-coupling, values as small as 1/(850 GeV)^{4} and 1/(1.9 TeV)^2 can be probed in the light Higgs and higgsless cases respectively, which is an improvement by orders of magnitude over existing limits.
description: 37 pages, 6 figures
MEM and CLEAN Imaging of VLBA Polarisation Observations of Compact Active Galactic Nuclei
Creators: name: Coughlan, Colm
name: Gabuzda, Denise
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Maximum Entropy Method (MEM) for the deconvolution of radio interferometry images is mathematically well based and presents a number of advantages over the usual CLEAN deconvolution, such as appreciably higher resolution. The application of MEM for polarisation imaging remains relatively little studied. CLEAN and MEM intensity and polarisation techniques are discussed in application to recently obtained 18cm VLBA polarisation data for a sample of Active Galactic Nuclei.
description: From the proceedings of Beamed and Unbeamed Gamma-Rays from Galaxies, April 11-15, 2011, Muonio, Finland. 6 pages, 3 figures
Explainability in Cybersecurity Data Science
Creators: name: Mellon, Jeffrey
name: Worrell, Clarence
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: Software Engineering

description: Cybersecurity is data-rich and therefore a natural setting for machine learning (ML). However, many challenges hamper ML deployment into cybersecurity systems and organizations. One major challenge is that the human-machine relationship is rooted in a lack of explainability. Generally, there are two directions of explainability in cybersecurity data science: Model-to-Human: predictive models inform the human cyber experts Human-to-Model: human cyber experts inform the predictive models When we build systems that combine both directions, we encourage a bidirectional, continuous relationship between the human and machine. We consider the absence of this two-way relationship a barrier to adopting ML systems at the cybersecurity-operations level. On a very basic level, explainable cybersecurity ML can be achieved now, but there are opportunities for significant improvement. In this blog, we first provide an overview of explainability in ML. Next, we illustrate (1) model-to-human explainability with the ML model form of cybersecurity decision trees. We then illustrate (2) human-to-model explainability with the feature engineering step of a cybersecurity ML pipeline. Finally, motivated by the progress made toward physics-informed ML, we recommend research needed to advance cybersecurity ML to achieve the level of two-way explainability necessary to encourage use of ML-based systems at the cybersecurity operations level.
Refined Metallicity Indices for M Dwarfs Using the SLoWPoKES Catalog of Wide, Low-mass Binaries
Creators: name: Dhital, Saurav
name: West, Andrew A.
name: Stassun, Keivan G.
name: Bochanski, John J.
name: Massey, Angela P.
name: Bastien, Fabienne A.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the results from spectroscopic observations of 113 ultra-wide, low-mass binary systems, composed largely of M0--M3 dwarfs, from the SLoWPoKES catalog of common proper motion pairs identified in the Sloan Digital Sky Survey. Radial velocities of each binary member were used to confirm that they are co-moving and, consequently, to further validate the high fidelity of the SLoWPoKES catalog. Ten stars appear to be spectroscopic binaries based on broad or split spectral features, supporting previous findings that wide binaries are likely to be hierarchical systems. We measured the Hα equivalent width of the stars in our sample and found that components of 81% of the observed pairs has similar Hα levels. The difference in Hα equivalent width amongst components with similar masses was smaller than the range of Hα variability for individual objects. We confirm that the Lepine et al. ζ(CaH2+CaH3, TiO5) index traces iso-metallicity loci for most of our sample of M dwarfs. However, we find a small systematic bias in ζ, especially in the early-type M dwarfs. We use our sample to recalibrate the definition of ζ. While representing a small change in the definition, the new ζ is a significantly better predictor of iso-metallicity for the higher mass M dwarfs.
description: Accepted for publication in AJ, 10 pages
Additional file 1 of Chemoresistance is mediated by ovarian cancer leader cells in vitro
Creators: name: Karimnia, Nazanin
name: Wilson, Amy L.
name: Green, Emma
name: Matthews, Amelia
name: Jobling, Thomas W.
name: Plebanski, Magdalena
name: Bilandzic, Maree
name: Stephens, Andrew N.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1.
The application gap : genomics for biodiversity and ecosystem service management
Creators: name: Heuertz, Myriam
name: Träger, Sabrina
name: [Und Viele Weitere]
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 577

description: The conservation of biodiversity from the genetic to the community levels is fundamental for the continual provision of ecosystem services (ES), the benefits that ecosystems provide to people. Genetic and genomic diversity enhance the resilience of populations and communities that underpin the provision of ecosystem functions and services. We show that genomics applications are mostly limited to flagship species and that their benefits for biodiversity conservation and ES management are underachieved. We propose a framework on how genomics applications can guide management for biodiversity conservation and sustainable ES to bridge this genomics-ES management ‘application gap’. We review how genomic knowledge in single species (relatedness, potentially adaptive variants) or in interacting species (host-microorganism coevolution, hybridization) can guide effective management actions. These include population supplementation, assisted migration or hybridization to promote climate-adapted variants or adaptive potential, control of invasives, delimitation of conservation or management areas, provenancing strategies for restoration, managing microbial function and solving conservation and ES trade-offs. Genomics-informed management actions for improved conservation and ES outcomes are supported through synergies between scientists and ES managers at local, regional and international levels, through the development of standardized genomic workflows, training to ES managers and incorporation of local information. Such actions facilitate the implementation of biodiversity conservation and ES policies such as the UN 2030 sustainable development goals and the EU Biodiversity strategy for 2030, and support the inclusion of ambitious biodiversity conservation goals in the development of new policies such as the CBD post-2020 Global Biodiversity Framework or conservation policies on hybrids.
Transient optimization model for simple pipeline systems
Creators: name: McInnis, Duncan Arthur, 1953-
Publisher: name: Engineering
Year: 1987
Subjects: subject: TC 163 M196 1988
subject: Hydraulic models
subject: Pipelines - Design and construction
subject: Transients (Dynamics) - Analysis
subject: Pipe - Fluid dynamics

description: Bibliography: p. 128-133.
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
Creators: name: Hoeft, Konrad
name: Kranz, Jennifer
name: [Und Viele Weitere]
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Fibrosis represents the common end stage of chronic organ injury independent of the initial insult, destroying tissue architecture and driving organ failure. Here we discover a population of profibrotic macrophages marked by expression of Spp1, Fn1, and Arg1 (termed Spp1 macrophages), which expands after organ injury. Using an unbiased approach, we identify the chemokine (C-X-C motif) ligand 4 (CXCL4) to be among the top upregulated genes during profibrotic Spp1 macrophage differentiation. In vitro and in vivo studies show that loss of Cxcl4 abrogates profibrotic Spp1 macrophage differentiation and ameliorates fibrosis after both heart and kidney injury. Moreover, we find that platelets, the most abundant source of CXCL4 in vivo, drive profibrotic Spp1 macrophage differentiation. Single nuclear RNA sequencing with ligand-receptor interaction analysis reveals that macrophages orchestrate fibroblast activation via Spp1, Fn1, and Sema3 crosstalk. Finally, we confirm that Spp1 macrophages expand in both human chronic kidney disease and heart failure.
Vanishing Viscous Limits for 3D Navier-Stokes Equations with A Navier-Slip Boundary Condition
Creators: name: Wang, Lizhen
name: Xin, Zhouping
name: Zang, Aibin
Publisher: name: arXiv
Year: 2012
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q30, 35Q35

description: In this paper, we investigate the vanishing viscosity limit for solutions to the Navier-Stokes equations with a Navier slip boundary condition on general compact and smooth domains in $\mathbf{R}^3$. We first obtain the higher order regularity estimates for the solutions to Prandtl's equation boundary layers. Furthermore, we prove that the strong solution to Navier-Stokes equations converges to the Eulerian one in $C([0,T];H^1(Ω))$ and $L^\infty((0,T)\timesø)$, where $T$ is independent of the viscosity, provided that initial velocity is regular enough. Furthermore, rates of convergence are obtained also.
description: 45pages
The impact of brain lesions on health-related quality of life in patients with WHO CNS grade 3 or 4 glioma : a lesion-function and resting-state fMRI analysis
Creators: name: Heinzel, Alexander
name: Mottaghy, Felix
name: Filß, Christian
name: Stoffels, Gabriele
name: Lohmann, Philipp
name: Friedrich, Michel
name: Shah, Nadim Jon
name: Caspers, Svenja Inga Verena
name: Weiß Lucas, Carolin
name: Ruge, Maximilian Ingolf
name: Galldiks, Norbert
name: Fink, Gereon R.
name: Langen, Karl-Josef
name: Kocher, Martin
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Purpose: In glioma patients, tumor development and multimodality therapy are associated with changes in health-related quality of life (HRQoL). It is largely unknown how different types and locations of tumor- and treatment-related brain lesions, as well as their relationship to white matter tracts and functional brain networks, affect HRQoL. Methods: In 121 patients with pretreated gliomas of WHO CNS grades 3 or 4, structural MRI, O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET, resting-state functional MRI (rs-fMRI) and self-reported HRQoL questionnaires (EORTC QLQ-C30/BN20) were obtained. Resection cavities, T1-enhancing lesions, T2/FLAIR hyperintensities, and lesions with pathologically increased FET uptake were delineated. Effects of tumor lateralization, involvement of white matter tracts or resting-state network nodes by different types of lesions and within-network rs-fMRI connectivity were analyzed in terms of their interaction with HRQoL scores. Results: Right hemisphere gliomas were associated with significantly less favorable outcomes in physical, role, emotional and social functioning, compared with left-sided tumors. Most functional HRQoL scores correlated significantly with right-sided white-matter tracts involvement by T2/FLAIR hyperintensities and with loss of within-network functional connectivity of right-sided nodes. Tumors of the left hemisphere caused significantly more communication deficits. Conclusion: In pretreated high-grade gliomas, right hemisphere lesions are associated with reduced HRQoL scores in most functional domains except communication ability, compared to tumors of the left hemisphere. These relationships are mainly observed for T2/FLAIR lesions involving structural and functional networks in the right hemisphere. The data suggest that sparing the right hemisphere from treatment-related tissue damage may improve HRQoL in glioma patients.
Local identification of groundwater dependent vegetation using high-resolution Sentinel-2 data : a Mediterranean case study
Creators: name: El-Hokayem, Léonard
name: Vita, Pantaleone
name: Conrad, Christopher
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 550

description: Groundwater dependent ecosystems (GDEs) are biodiversity hotspots and provide important ecosystem services. This study presents a novel multi-instrument concept for the local identification of groundwater dependent vegetation (GDV) in the Mediterranean. The concept integrates high-resolution Sentinel-2 remote sensing data with available geodata and requires in situ vegetation data for validation and calibration. The approach combines five criteria to identify GDV: 1) high vitality, and wetness during dry period, 2) low seasonal changes in vitality and leaf area, 3) low interannual changes in vitality, 4) high topographic potential of water accumulation and low water table depth, 5) high potential inflow dependency. Iso Cluster Unsupervised Classification (ICUC) was applied to identify GDV in the study area (Campania, Italy). Botanical field mapping was utilized for validating the remote sensing approach, as it exhibited significant differences between GDV and Non-GDV in terms of ecohydrological indicator values, leaf anatomy and phreatophyte coverage. According to a new simple ecohydrological rule set that considers phreatophyte cover and mean moisture value of non-phreatophyte species, 9% of vegetation plots are considered GDV and 33% likely GDV. 80% of all GDV derived from classification occur in hydrostratigraphic units (HSU) that are characterized by surficial groundwater circulation and low permeability. The overall accuracy of classifying likelihoods is 62.7%. For 14.6% of the plots, non-GDVs were classified as GDVs (false positives), and only one GDV plot has been classified falsely as non-GDV (false negative). Local results on GDV locations can be overlayed with aquifer use or aquifer reaction to climate change in order to identify GDV under threat and implement sustainable managements of groundwater resources.
On the spectral shape of radiation due to Inverse Compton Scattering close to the maximum cut-off
Creators: name: Lefa, E.
name: Kelner, S. R.
name: Aharonian, F. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The spectral shape of radiation due to Inverse Compton Scattering is analyzed, in the Thomson and the Klein-Nishina regime, for electron distributions with exponential cut-off. We derive analytical, asymptotic expressions for the spectrum close to the maximum cut-off region. We consider monoenergetic, Planckian and Synchrotron photons as target photon fields. These approximations provide a direct link between the distribution of parent electrons and the up-scattered spectrum at the cut-off region.
description: 27 pages, 15 figures, accepted for publication in ApJ
Identifying discontinuities of flood frequency curves
Creators: name: Miniussi, Adrianna
name: Merz, Ralf
name: Kaule, Lisa
name: Basso, Stefano
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 551

description: Discontinuities in flood frequency curves, here referred to as flood divides, hinder the estimation of rare floods. In this paper we develop an automated methodology for the detection of flood divides from observations and models, and apply it to a large set of case studies in the USA and Germany. We then assess the reliability of the PHysically-based Extreme Value (PHEV) distribution of river flows to identify catchments that might experience a flood divide, validating its results against observations. This tool is suitable for the identification of flood divides, with a high correct detection rate especially in the autumn and summer seasons. It instead tends to indicate the emergence of flood divides not visible in the observations in spring and winter. We examine possible reasons of this behavior, finding them in the typical streamflow dynamics of the concerned case studies. By means of a controlled experiment we also re-evaluate detection capabilities of observations and PHEV after discarding the highest maxima for all cases where both empirical and theoretical estimates display flood divides. PHEV mostly confirms its capability to detect a flood divide as observed in the original flood frequency curve, even if the shortened one does not show it. These findings prove its reliability for the identification of flood divides and set the premises for a deeper investigation of physiographic and hydroclimatic attributes controlling the emergence of discontinuities in flood frequency curves.
On the Wulff construction as a problem of equivalence of statistical ensembles
Creators: name: Miracle-Sole, Salvador
name: Ruiz, Jean
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 82B05, 82B20, 82B24

description: The statistical mechanics of SOS (solid-on-solid) 1-dimensional models under the global constraint of having a specified area between the interface and the horizontal axis, is studied. We prove the existence of the thermodynamic limits and the equivalence of the corresponding statistical mechanics. This gives a simple alternative microscopic proof of the validity of the Wulff construction for such models.
description: 11 pages, 1 figure
Applying generic landscape-scale models of natural pest control to real data : associations between crops, pests and biocontrol agents make the difference
Creators: name: Bonato, Marta
name: Martin, Emily A.
name: Cord, Anna F.
name: Seppelt, Ralf
name: Beckmann, Michael
name: Strauch, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 550

description: Managing agricultural land to maximize the supply of natural pest control can help reduce pesticide use. Tools that are able to represent the relationship between landscape structure, field management and natural pest control can help in deciding which management practices should be used and where. However, the reliability and the predictive power of generic models of natural pest control is largely unknown. We applied an existing generic model of natural pest control potential based on landscape structure to nine sites in five European countries and tested the resulting values against field measurements of natural pest control. Subsequently, we added information on local level factors to test the possibility of improving model performance and predictive power. The results showed that there is generally little or no evidence of correlation between modeled and field-measured values of natural pest control. Moreover, we found high variability in the results, depending on the associations of crops, pests and biocontrol agents considered (e.g. Oilseed rape-Pollen beetle-Parasitoids) and on the different case studies. Factors at the local level, such as conservation tillage, had an overall positive effect on natural pest control, and their inclusion in the models typically increased their predictive power. Our results underline the importance of developing predictive models of natural pest control which are tailored towards specific associations between crops, pests and biocontrol agents, consider local level factors and are trained using field measurements. They would serve as important tools within farmers' decision making, ultimately supporting the shift toward a low-pesticide agriculture.
Electronic structure study of TiO2 polymorphs, evaluation of formic acid adsorption on dry (001) and (100) TiO2(B) facets by DFT calculations
Creators: name: Fernández-Werner, Luciana
name: Faccio, Ricardo
name: Pardo, Helena
name: Mombrú, Álvaro W.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Structural and electronic properties comparison between anatase, rutile and monoclinic TiO2(B) titania polymorphs in bulk and related nanostructures simulated by two-dimensional slabs has been performed by means of density functional theory calculations. TiO2(B) was included due to experimental results where it appears as a metastable phase during thermal annealing of low content sodium layered titanate nanostructures obtained via hydrothermal synthesis. Band gaps and surface energies are discussed confronting results obtained by Plane Waves (PW) and Localized Basis Set methods (LCNAO), observing an excellent agreement between both methodologies when considering floating basis to calculate surfaces energies using LCAO. The computed formation energy for the TiO2(B) (001) slab, as has been previously reported by Vittadini A. et al., J. Phys. Chem. C 2009, 113 (44), 18973-18977, is in the order of the one calculated for anatasa (101) which represents one of the most stable TiO2 surfaces. The adsorption of formic acid on (001) and (100) - less stable - TiO2(B) dry facets was investigated as the first step for further evaluation of TiO2(B) nanostructures for dye sensitized solar cells (DSSC) applications. The results show that the bidentate dissociated configuration is the most stable for both surfaces being the computed adsorption energy 0.76 eV and 1.35 eV for (001) and (100) respectively. These results differ from what was previously found for dry anatasa (101) where monodentate coordination prevails. The evaluated reactivity of TiO2(B) slabs is comparable with anatase and indicates that it could be a good adsorbent for common dyes used for Dye Sensitized Solar Cells purposes.
description: 20 pages, 10 Figures, 6 Tables, submitted
0093 The Battle of Orsha – court propaganda or chivalric epic?
Creators: name: Hucul, Volodymyr
name: Kolenda, Karolina
Publisher: name: RIHA Journal
Year: 2014

description: The Battle of Orsha, part of the collection of the National Museum in Warsaw, an example of panel painting (1525–1535), is of paramount importance for the study of the military, as well as for the research in art history, material history, and the history of political and military elites of Central-Eastern Europe during the Renaissance. The article describes the ways Ruthenian and Lithuanian-Polish elites used material and intellectual products of chivalric culture, and tackles the problem of documentary and propagandist role of visual narrative. Since the publication of works by David Freedberg1 and Peter Burke2 the necessity to recreate the context of making, functioning, and reception of images has become evident. Daniel Arasse has further expanded methodological tools of this type of research3. However, there are still numerous artworks whose historical and social context has either remained untouched by research, or has been researched insufficiently. Repeatedly, it has led to misinterpretations of such artworks in spite of their major position in culture. The Battle of Orsha is a spectacular example of this process.
description: RIHA Journal, 2014: RIHA Journal
The low energy frontier: What is exciting about physics below the top RHIC energy
Creators: name: Bleicher, Marcus
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: These proceedings summarize my plenary talk at Quark Matter 2011 with a focus on the future perspectives of the low energy programs at RHIC, FAIR, NICA and CERN.
description: Proceedings of Quark Matter 2011
Additional file 1 of De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Creators: name: Moosavi, Seyed H.
name: Eide, Peter W.
name: Eilertsen, Ina A.
name: Brunsell, Tuva H.
name: Berg, Kaja C. G.
name: Røsok, Bård I.
name: Brudvik, Kristoffer W.
name: Bjørnbeth, Bjørn A.
name: Guren, Marianne G.
name: Nesbakken, Arild
name: Lothe, Ragnhild A.
name: Sveen, Anita
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: R codes for the data analyses. Fig. S1. Overview of study material and analyses. Fig. S2. The impact of batch correction on sample type comparisons. Fig. S3. Association between selected clinical parameters and gene expression profiles of CRLMs. Fig. S4. CMS subtyping of CRLMs using the tailored CMS classifier. Fig. S5. GSEA of the epithelial versus mesenchymal subtype from K = 2 factorization. Fig. S6. PCA and liver score distribution among LMS groups. Fig. S7. Selected single-sample GSVA scores across the LMS groups. Fig. S8. GSEA in CRLMs with RAS/TP53 co-mutations. Fig. S9. Kaplan–Meier plots of 5-year CSS according to LMS and translated CMS subtypes. Fig. S10. Kaplan–Meier plots of 5-year OS and CSS according to epithelial and mesenchymal subtypes. Fig. S11. Kaplan–Meier plots of 5-year OS and CSS according to LMS and TP53/RAS co-mutations. Fig. S12. CRIS classification of the in-house CRLM samples. Fig. S13. GSEA of CRLMs in two external datasets according to LMS. Fig. S14. De novo transcriptomic subtyping by unsupervised NMF of the two external CRLM datasets. Fig. S15. Kaplan–Meier curves of OS and CSS according to LMS1 and tumor heterogeneity. Fig. S16. LMS1 mini-classifier is correlated with signatures of LMS1 characteristics. Fig. S17. LMS1 mini-classifier captures the poor-prognostic value of LMS1.
Inhalt des 15. Jahrgangs
Creators: name: Redaktion, Die
Publisher: name: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete
Year: 2020

description: Trierer Zeitschrift - Archäologie und Kunst des Trierer Landes und seiner Nachbargebiete, Bd. 15 (1940): Trierer Zeitschrift : für Geschichte und Kunst des Trierer Landes und seiner Nachbargebiete
Die germanische Siedlung in Haldern bei Wesel am Niederrhein
Creators: name: Uslar, R. V.
Publisher: name: Bonner Jahrbücher
Year: 2020

description: -
description: Bonner Jahrbücher, Bd. 149 (1949): Bonner Jahrbücher des Vereins von Altertumsfreunden im Rheinlande und des Rheinischen Provinzialmuseums in Bonn
Understanding critical behavior in the framework of the extended equilibrium fluctuation theorem
Creators: name: Velazquez, L.
name: Curilef, S.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Recently (arXiv:0910.2870), we have derived a fluctuation theorem for systems in thermodynamic equilibrium compatible with anomalous response functions, e.g. the existence of states with \textit{negative heat capacities} $C<0$. In this work, we show that the present approach of the fluctuation theory introduces new insights in the understanding of \textit{critical phenomena}. Specifically, the new theorem predicts that the environmental influence can radically affect critical behavior of systems, e.g. to provoke a suppression of the divergence of correlation length $ξ$ and some of its associated phenomena as spontaneous symmetry breaking. Our analysis reveals that while response functions and state equations are \emph{intrinsic properties} for a given system, critical behaviors are always \emph{relative phenomena}, that is, their existence crucially depend on the underlying environmental influence.
The volitional self-contradiction interpretation of Kant’s formula of universal law : a Response to Kleingeld
Creators: name: Walschots, Michael
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 100

description: In this paper I critically engage with Pauline Kleingeld’s ‘volitional self-contradiction’ interpretation of Kant’s formula of universal law. I make three remarks: first, I seek to clarify what it means for a contradiction to be volitional as opposed to logical; second, I suggest that her interpretation might need to be closer to Korsgaard’s ‘practical contradiction’ interpretation than she thinks; and third, I suggest that more work needs to be done to explain how a volitional self-contradiction generates both a ‘contradiction in conception’ and a ‘contradiction in will.’
Generative AI Q&A: Applications in Software Engineering
Creators: name: Robert, John
name: Schmidt, Douglas
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: Software Engineering

description: The SEI recently hosted a question and answer webcast on generative AI. This webinar featured experts from across the SEI answering questions posed by the audience and discussing both the technological advancements and the practical considerations necessary for effective and reliable application of generative AI and large language models (LLMs), such as ChatGPT and Claude. This blog post includes our responses, which have been reordered and edited to enhance the clarity of the original webcast. It is the first of part a two-part series and explores the implications of generative AI in software engineering, particularly in the context of defense and domains with stringent quality-of-service requirements. In this part, we discuss the transformative impacts of generative AI on software engineering as well as its practical implications and adaptability in mission-critical environments.
MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell-mediated cytolysis
Creators: name: Pane, Antonino A.
name: Kordaß, Theresa
name: Hotz-Wagenblatt, Agnes
name: Dickes, Elke
name: Kopp-Schneider, Annette
name: Will, Rainer D.
name: Seliger, Barbara
name: Osen, Wolfram
name: Eichmüller, Stefan B.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Background: The regulatory functions ofmicroRNAs (miRNAs) in anti-tumour immunity have been mainly described in immune effector cells. Since little is known about miRNA effects on the susceptibility of target cells during T cell—target cell interaction, this study focused on the identification of miRNAs expressed in tumour cells controlling their susceptibility to CD8+ T cell-mediated cytotoxicity. Methods: Luciferase expressing B16F10 melanoma (B16F10 Luci+) cells transfected with individual miRNAs covering a comprehensive murine miRNA library were screened for their susceptibility to lysis by an established cytotoxic T lymphocyte (CTL) line (5a, clone Nβ) specific for the melanoma-associated antigen tyrosinase-related protein 2.miRNAs with the most pronounced effects on T cell-mediated lysis were validated and stably expressed in B16F10 cells. In silico analyses identified common targets of miRNA sets determined by the screen, which were further confirmed by small interfering RNA (siRNA)-mediated silencing experimentsmodulating immune surveillance. The Ingenuity Pathway Analysis (IPA) software and RNA sequencing (RNA-seq) data from miRNAoverexpressing cell lineswere applied to investigate the underlying mechanisms. The Cancer Genome Atlas (TCGA)-derived miRNA sequencing data were used to assess the correlation of miRNA expression with melanoma patients’ survival. Results: The miRNA screen resulted in the selection of seven miRNAs enhancing CTL-mediated melanoma cell killing in vitro. Upon stable overexpression of selected miRNAs, hsa-miR-320a-3p, mmu-miR-7037-5p and mmu-miR-666- 3p were determined as most effective in enhancing susceptibility to CTL lysis. In silico analyses and subsequent siRNA-mediated silencing experiments identified Psmc3 and Ndufa1 as common miRNA targets possibly involved in the functional effects observed. The analyses of RNA-seq data with IPAshowed pathways, networks, biological functions and key molecules potentially involved in the miRNA-mediated functional effects. Finally, based on TCGA data analysis, a positive correlation of the conserved miRNAs among the panel of the seven identified miRNAs with overall survival of melanoma patients was determined. Conclusions: For the first time, this study uncoveredmiRNA species that affect the susceptibility of melanoma cells to T cell-mediated killing. These miRNAs might represent attractive candidates for novel therapy approaches against melanoma and other tumour entities.
Additional file 1 of Novel approach of dermatophytosis eradication in shelters: effect of Pythium oligandrum on Microsporum canis in FIV or FeLV positive cats
Creators: name: Načeradská, Martina
name: Fridrichová, Michaela
name: Kolářová, Martina Frühauf
name: Krejčová, Tereza
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1.
Nursing care for the liver transplant recipient in the postoperative period: an integrative literature review
Creators: name: Dal Sasso Mendes, Karina
name: Ferreira, Isabella
name: Nakano, Nataly
name: Galvão, Cristina
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Perioperative, Operating Room and Surgical Nursing
subject: Medicine and Health Sciences
subject: Nursing
subject: FOS: Health sciences
subject: Integrative Review
subject: Liver transplantation
subject: Nursing care

description: This is an integrative review protocol to aim to analyze the evidence available in the literature on nursing care provided to the liver transplant recipient in the postoperative period. To conduct this IR, the following steps will be followed: development of the research question, sampling or literature search of primary studies, data extraction, evaluation of primary studies, analysis and synthesis of results, and presentation of the review. The research question delimited for the elaboration of the IR will be "What is the available evidence in the literature on nursing care to the liver transplant recipient in the postoperative period?" The search for primary studies will be performed via internet, and the selected databases will be: US Natonal Library of Medicine (PUBMED), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Latin American and Caribbean Literature on Health Sciences (LILACS). The delimited inclusion criteria will be: primary studies that portray nursing care to the liver transplant recipient in the postoperative period, published in English, Portuguese and Spanish, in the period from January 2018 to December 2022. Grey literature, case reports, abstracts of scientific events, editorials or letter-response will be excluded. Searches from each database will be organized in EndNote X7 reference manager (Desktop version) and duplicates will be removed.(11) The web application Rayyan Systems(12) will be used for the selection of studies, which will be performed in two stages: selection of titles and abstracts (phase 1) and reading in full (phase 2). This process will be performed by two reviewers, with the presence of a third reviewer to resolve conflicts.
Antioxidant and anti-tyrosinase activities of quercetin-loaded olive oil nanoemulsion as potential formulation for skin hyperpigmentation
Creators: name: Silva, Cristiane C.
name: Benati, Rogério B.
name: Massaro, Taís N. C.
name: Pereira, Karina C.
name: Gaspar, Lorena R.
name: Marcato, Priscyla D.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Hyperpigmentation disorders are characterized by dark spots on the skin. Treatment for hypermelanosis involves the application of tyrosinase inhibitors, chemical peels, or lasers therapy, although they may cause skin irritation and other side effects. Potential natural alternatives for skin hyperpigmentation are quercetin (QT) and olive oil (OL) due to their antioxidant activity and anti-tyrosinase property. However, QT usage drawback is its low water solubility and high chemical instability that may be overcome with nanoencapsulation. To understand if QT and OL could be used as alternative to improve hypermelanosis, we evaluated the physical-chemical and biological properties of quercetin-loaded olive oil nanoemulsion (QT-NE). QT-NE was prepared by the high-energy emulsification method and, through the Box-Behnken design, we analyzed different concentrations of OL, surfactant mixture, and the agitation speed in relation to diameter and polydispersity index (PdI). The optimized formulation was characterized in terms of size, PdI, zeta potential, pH, electrical conductivity, stability and encapsulation efficiency. Besides, we evaluated in vitro antioxidant activity, tyrosinase inhibitory activity, and in vitro toxicity. The optimized QT-NE showed a size of 183.43 ± 9.53 nm with low PdI (∼0.19), zeta potential of −17.13 ± 0.61 mV, pH around 7, conductivity of 163.96 ± 8.92 µS/cm, and high encapsulation efficiency (∼99%). The QT-NE exhibited high antioxidant activity (∼92%) and inhibited 56% of tyrosinase activity, indicating its potential for free radical scavenging and reducing skin hyperpigmentation. Furthermore, no irritation was observed by HET-CAM. Thus, this nanoemulsion (NE) is a promising alternative for hypermelanosis and could substitute the current treatments.
Environmental risk factors of incident distal sensorimotor polyneuropathy : results from the prospective population-based KORA F4/FF4 study
Creators: name: Herder, Christian
name: Zhang, Siqi
name: Wolf, Kathrin
name: Maalmi, Haifa
name: Bönhof, Gidon Josia
name: Rathmann, Wolfgang
name: Schwettmann, Lars
name: Thorand, Barbara
name: Roden, Michael
name: Schneider, Alexandra
name: Ziegler, Dan
name: Peters, Annette
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Distal sensorimotor polyneuropathy (DSPN) is a common condition in older populations with high prevalence of obesity and type 2 diabetes. We hypothesised that the risk of DSPN is increased by multiple ubiquitous environmental risk factors, particularly in people with obesity. This study was based on 423 individuals aged 62–81 years without DSPN who participated in the population-based Cooperative Health Research in the Region of Augsburg (KORA) F4 survey (2006–2008) in Southern Germany. During 6.5 years of follow-up, 188 participants developed clinical DSPN as assessed by the Michigan Neuropathy Screening Instrument. Environmental exposures, including air temperature, surrounding greenness (assessed with the normalized difference vegetation index [NDVI]), long-term road traffic noise and air pollution, were assessed at participants' residences. The cumulative risk index (CRI) evaluated the joint effects of co-occurring exposures on DSPN risk based on effect estimates from multi-exposure Poisson regression models. The models were adjusted for age, sex, height, waist circumference, smoking, alcohol consumption, physical activity, education and neighbourhood socioeconomic status. In the entire cohort, the co-occurrence of an interquartile range (IQR) decrease in temperature of the warm season and NDVI in a 100-m buffer and of an IQR increase in night-time average traffic noise and in annual average particle number concentration (PNC) was positively associated with incident DSPN (CRI [95 % CI] 1.39 [1.02, 1.91]). Effect estimates for exposure combinations were generally higher in individuals with obesity (CRI 1.34–2.01) than in those without obesity (CRI 0.90–1.33). The four-exposure model showed a twofold increased risk of DSPN among obese (CRI [95 % CI] 2.01 [1.10, 3.67]), but not among non-obese individuals (CRI [95 % CI] 1.18 [0.83, 1.67]). Thus, ubiquitous environmental exposures jointly augment the risk of DSPN in the older population. Lower air temperature in the warm season, less greenness, and higher noise levels and ultrafine particle concentrations identified people with obesity as a particularly vulnerable subgroup.
Orbit equivalence types of circle diffeomorphisms with a Liouville rotation number
Creators: name: Matsumoto, Shigenori
Publisher: name: arXiv
Year: 2012
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 37E10

description: This paper is concerned about the orbit equivalence types of $C^\infty$ diffeomorphisms of $S^1$ seen as nonsingular automorphisms of $(S^1,m)$, where $m$ is the Lebesgue measure. Given any Liouville number $α$, it is shown that each of the subspace formed by type ${\rm II}_1$, ${\rm II}_\infty$, ${\rm III}_λ$ ($λ>1$), ${\rm III}_\infty$ and ${\rm III}_0$ diffeomorphisms are $C^\infty$-dense in the space of the orientation preserving $C^\infty$ diffeomorphisms with rotation number $α$.
description: 14 pages, 2 figures