cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
L’uso del ‘bianco’ nel restauro architettonico a Roma nel XIX secolo
Creators: name: Muratore, Olivia
Publisher: name: Opus Incertum
Year: 2017

description: The essay highlights how the debate on the approach to restoration interventions that is still currently ongoing, could already be recognised in the great restoration projects carried out in Rome in the first two decades of the 19th century, together with some of the maintenance practices undertaken throughout the whole century. Attention is especially placed on the external finishings of architectural structures, and in the practice of the so-called whitewashing of the facades during the 19th century. Although very commonly used for conservation and urban regeneration purposes, these practeces were strongly criticised and occasionally attacked by personalities of the field of restoration that were more sensitive to the importance of safeguarding the 'patina' which time had left on the surface of architectural structures, and that would otherwise be inevitably lost. Some of today's theoreticians of restoration find food for thought in those issues, which they continue to propose as an element for discussion amongst the various positions which see in the treatment of the surfaces of historical architecture a fertile ground for methodological debate.
description: Opus Incertum, Vol 2 (2016)
A proportional hazards regression model for the subdistribution with right-censored and left-truncated competing risks data
Creators: name: Zhang, Mei-Jie
name: Zhang, Xu
name: Fine, Jason
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: With competing risks failure time data, one often needs to assess the covariate effects on the cumulative incidence probabilities. Fine and Gray proposed a proportional hazards regression model to directly model the subdistribution of a competing risk. They developed the estimating procedure for right-censored competing risks data, based on the inverse probability of censoring weighting. Right-censored and left-truncated competing risks data sometimes occur in biomedical researches. In this paper, we study the proportional hazards regression model for the subdistribution of a competing risk with right-censored and left-truncated data. We adopt a new weighting technique to estimate the parameters in this model. We have derived the large sample properties of the proposed estimators. To illustrate the application of the new method, we analyze the failure time data for children with acute leukemia. In this example, the failure times for children who had bone marrow transplants were left truncated.
Discrete-time semi-Markov modeling of human papillomavirus persistence
Creators: name: Lo, Y.
name: Rompalo, A.
name: King, C. C.
name: Smith, J. S.
name: Hudgens, M. G.
name: Mitchell, C. E.
name: Sobel, J.
name: Cu-Uvin, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Multi-state modeling is often employed to describe the progression of a disease process. In epidemiological studies of certain diseases, the disease state is typically only observed at periodic clinical visits, producing incomplete longitudinal data. In this paper we consider fitting semi-Markov models to estimate the persistence of human papillomavirus (HPV) type-specific infection in studies where the status of HPV type(s) is assessed periodically. Simulation study results are presented indicating the semi-Markov estimator is more accurate than an estimator currently used in the HPV literature. The methods are illustrated using data from the HIV Epidemiology Research Study (HERS).
Costruzioni letterarie e valori cromatici nel Danteum di Pietro Lingeri e Giuseppe Terragni
Creators: name: Albarello, Carlo
Publisher: name: Opus Incertum
Year: 2017

description: In 1938 Giuseppe Terragni and Pietro Lingeri designed the Danteum, a monument to be erected in the new via dei Fori Imperiali in Rome. The project area, before the Basilica di Massenzio, is endowed with special symbolic value, since during the Fascist period this was already considered a suitable site for the architectural competition for a Palazzo Littorio. Both in the 1934 competition and in the 1938 project the problems connected to the inclusion of new elements onto the ancient remains called into question the chromatic issue as one which designers should take into far greater account. In this respect, the Danteum is the monument that more than others displays a quite interesting sequence of spacial structures which parallel Dante’s work while, at the same time, offering a peculiar chromatic synthesis in the ideal and material relationship with the various features of the historical period and the archaeological site. In this work the resulting mix of literary and architectural language was to serve as a tool to promote the ideology of the Fascist regime, while making of Dante Alighieri, through his work and thought, the interpreter of an autocratic view of political power.
description: Opus Incertum, Vol 2 (2016)
Parametric mixture models to evaluate and summarize hazard ratios in the presence of competing risks with time-dependent hazards and delayed entry
Creators: name: Gange, Stephen J.
name: Lau, Bryan
name: Cole, Stephen R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: In the analysis of survival data, there are often competing events that preclude an event of interest from occurring. Regression analysis with competing risks is typically undertaken using a cause-specific proportional hazards model. However, modern alternative methods exist for the analysis of the subdistribution hazard with a corresponding subdistribution proportional hazards model. In this paper, we introduce a flexible parametric mixture model as a unifying method to obtain estimates of the cause-specific and subdistribution hazards and hazard ratio functions. We describe how these estimates can be summarized over time to give a single number that is comparable to the hazard ratio that is obtained from a corresponding cause-specific or subdistribution proportional hazards model. An application to the Women’s Interagency HIV Study is provided to investigate injection drug use and the time to either the initiation of effective antiretroviral therapy, or clinical disease progression as a competing event.
Motion Energy Analysis (MEA)
Creators: name: Ramseyer, Fabian
name: , Jaemin
name: Ehkirch, Quentin
Publisher: name: Open Science Framework
Year: 2019
Subjects: subject: interpersonal coordination
subject: motion energy analysis
subject: nonverbal synchrony
subject: mimicry
subject: embodiment

description: Sample data, instructional movies, and Manual for MEA.
Sample size and power determination in joint modeling of longitudinal and survival data
Creators: name: Ibrahim, Joseph G.
name: Chen, Liddy M.
name: Chu, Haitao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Owing to the rapid development of biomarkers in clinical trials, joint modeling of longitudinal and survival data has gained its popularity in the recent years because it reduces bias and provides improvements of efficiency in the assessment of treatment effects and other prognostic factors. Although much effort has been put into inferential methods in joint modeling, such as estimation and hypothesis testing, design aspects have not been formally considered. Statistical design, such as sample size and power calculations, is a crucial first step in clinical trials. In this paper, we derive a closed-form sample size formula for estimating the effect of the longitudinal process in joint modeling, and extend Schoenfeld’s sample size formula to the joint modeling setting for estimating the overall treatment effect. The sample size formula we develop is quite general, allowing for p-degree polynomial trajectories. The robustness of our model is demonstrated in simulation studies with linear and quadratic trajectories. We discuss the impact of the within-subject variability on power and data collection strategies, such as spacing and frequency of repeated measurements, in order to maximize the power. When the within-subject variability is large, different data collection strategies can influence the power of the study in a significant way. Optimal frequency of repeated measurements also depends on the nature of the trajectory with higher polynomial trajectories and larger measurement error requiring more frequent measurements.
"Signals_Data_CMS_VV_JJ.tar" of "Search for massive resonances in dijet systems containing jets tagged as W or Z boson decays in pp collisions at sqrt(s)= 8 TeV"
Creators: name: CMS Collaboration
Publisher: name: HEPData
Year: 2015

description: Signal, Data and Background files
description: CERN-LHC. A search is reported for massive resonances decaying into a quark and a vector boson (W or Z), or two vector bosons (WW, WZ, or ZZ). The analysis is performed on an inclusive sample of multijet events corresponding to an integrated luminosity of 19.7 inverse femtobarns, collected in proton-proton collisions at a centre-of-mass energy of 8 TeV with the CMS detector at the LHC. The search uses novel jet-substructure identification techniques that provide sensitivity to the presence of highly boosted vector bosons decaying into a pair of quarks. Exclusion limits are set at a confidence level of 95% on the production of: (i) excited quark resonances q* decaying to qW and qZ for masses less than 3.2 TeV and 2.9 TeV, respectively, (ii) a Randall-Sundrum graviton G[RS] decaying into WW for masses below 1.2 TeV, and (iii) a heavy partner of the W boson W' decaying into WZ for masses less than 1.7 TeV. For the first time mass limits are set on W' to WZ and G[RS] to WW in the all-jets final state. The mass limits on q* to qW, q* to qZ, W' to WZ, G[RS] to WW are the most stringent to date. A model with a "bulk" graviton G[Bulk] that decays into WW or ZZ bosons is also studied. The data are provide for double W/Z tagged bihs: HIGH purity and LOW purity. The data driven background is also provided with 1 sigma PLUS and MINUS uncertainties. Those are the only uncertainties to be applied on the background. The statistical uncertainties on data can be derived from the number of events using your preferred approximation. A tar file contains: data in root format with background ucnertainties. Root files with Signal shapes corresponding to different hypotheses: W'-->WZ, Bulk Graviton-->WW, Bulk Graviton-->ZZ, RS Graviton --> WW, RS Graviton --> ZZ. The difference between Bulk Graviton and RS Graviton is the vector boson polarization: Longitudinal for Bulk Graviton and Transverse for RS Graviton. The number of events in those files are normalized assuming production cross section times branching fraction of 1 fb.
Supplementary document for Enhancing long-term frequency stability of actively mode-locked optoelectronic oscillator via phase-locked loop - 7125017.pdf
Creators: name: Wu, Haitao
name: Li, Zhaolong
name: Gui, Sibo
name: Shi, Meng
name: Zhao, Jy
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Supplement document for detailed heterodyne method principle and Allan Deviation calculation
Modified gravity, the Cascading DGP model and its critical tension
Creators: name: Sbisà, Fulvio
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We investigate the presence of instabilities in the Cascading DGP model. We start by discussing the problem of the cosmological late time acceleration, and we introduce the modified gravity approach. We then focus on brane induced gravity models and in particular on the Cascading DGP model. We consider configurations of the latter model where the source term is given simply by vacuum energy (pure tension), and we study perturbations at first order around these configurations. We perform a four-dimensional scalar-vector-tensor decomposition of the perturbations, and show that, regarding the scalar sector, the dynamics in a suitable limit can be described by a master equation. This master equation contains an energy scale (critical tension) which is related in a non-trivial way to the parameters of the model. We give a geometrical interpretation of why this scale emerges, and explain its relevance for the presence of ghost instabilities in the theory. We comment on the difference between our result and the one present in the literature, and stress its importance regarding the phenomenological viability of the model. We finally provide a numerical check which confirms the validity of our analysis.
description: 6 pages, 1 figure, published version (proceedings of the 5th Young Researchers Meeting)
Le radici del bianco nell’opera di Richard Meier
Creators: name: Zammerini, Massimo
Publisher: name: Opus Incertum
Year: 2017

description: Richard Meier’s work is the outcome of the revitalization of a vast linguistic-architectural heritage extending far beyond the Modernist experience. Meier subjectively rearranges the different roots of the Modern Movement employing a scientific attitude which looks back to the past from a typically American perspective, consisting in a rather free manipulation of the model for its immediate implementation in the present and its future reproducibility on a large scale. In the second half of the 20th century the architect takes a critical view of Modernism according to a research method which has something in common with the historical recovery of classical models typical of Neoclassicism. The work of Richard Meier stands out as having a real narrative pattern. Over time the artist improves and refines a kind of language which, though explicitly indebted to the work of Le Corbusier and his relationship with the Mediterranean Sea, pays closer and renewed attention to some spatial and language solutions. These, in turn, reflect and sum up relevant clues and suggestions drawn from the entire architectural heritage, going as far back as classical times, and take new life in the spaces and forms of its architecture where the presence of total white offers a valid solution to an otherwise inevitable short-circuit. The colour white artistically encapsulates the vast array of forms fixing them in a timeless frame.
description: Opus Incertum, Vol 2 (2016)
title: Эндометриоз: современное состояние проблемы
title: Endometriosis: current state of the issue
Creators: name: Гришкина, Анастасия Александровна
name: Башмакова, Надежда Васильевна
name: Чистякова, Гузель Нуховна
name: Ремизова, Ирина Ивановна
name: Мелкозерова, Оксана Александровна
Publisher: name: Издательский центр СурГУ
Year: 2020

description: Цель – провести обзор научной литературы, посвященной проблеме эндометриоза, и определить предполагаемые этиологические факторы и механизмы формирования патологии. Материал и методы. Проанализированы актуальные научные публикации отечественных и зарубежных ученых о возможных причинах и механизмах формирования патологии у женщин с эндометриозом, размещенные в базах данных КиберЛенинка, Scopus и PubMed. Результаты. Эндометриоз формируется на фоне изменений гормональной регуляции, факторов местного иммунитета, а также молекулярных нарушений и снижает функцию репродуктивной системы. При этом определение причин эндометриоза и механизмов его формирования до сих пор проблематично и требует дальнейшего изучения.
description: The study aims to analyze literature, devoted to the endometriosis and to define the alleged etiological factors and mechanisms for the pathology formation. Material and methods. The publications of Russian and foreign scientists from scientific databases such as CyberLeninka, Scopus, PubMed, were studied. Based on the analysis of the literature, possible causes and mechanisms of pathology formation in women with endometriosis are considered. Results. Endometriosis is formed in the presence of changes in hormonal regulation, factors of tissue immunity, and molecular disorders. This disease reduces the function of the reproductive system. At the same time, the problem of endometriosis with the determination of the causes and mechanisms of its formation remains unresolved and requires further study.
Enhanced ferrimagnetism in auxetic NiFe2O4 in the crossover to the ultrathin film limit
Creators: name: Hoppe, Michael
name: Döring, Sven
name: Gorgoi, Mihaela
name: Cramm, Stefan
name: Müller, Martina
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate the sensitive interplay between magnetic, electronic and structural properties in the ferrimagnetic oxide NiFe2O4. Emphasis is placed on the impact of reduced dimensionality in the crossover from bulk-like to ultrathin films. We observed an enhanced saturation magnetization $M_S$ for ultrathin NiFe2O4 films on Nb-SrTiO3 (001) substrates that co-occurs with a reduced out-of-plane lattice constant under compressive in-plane epitaxial strain. We found a bulk-like cationic coordination of the inverse spinel lattice independent of the NiFe2O4 film thickness -- thus ruling out a cationic inversion that nominally could account for an enhanced $M_S$. Our study instead uncovers a reduction of the unit cell volume, i.e. an auxetic behavior in ultrathin NiFe2O4 films, which may result in an enhanced magnetic exchange caused by an increased interatomic electronic localization.
description: 8 pages, 6 figures
The Prosocial Framework: Theory, Practice and Applications Within Schools
Creators: name: Gillard, D.
name: Jackson-Brown, F.
name: Stanley-Duke, M.
name: Atkins, P.
name: Anderson, B.
name: Balfour, E.
name: Cooper, P.
Publisher: name: School of Psychology, University of East London
Year: 2022

description: Recent collaborations across psychological and evolutionary science have resulted in the emergence of an intervention programme for increasing the cohesion and effectiveness of human group processes. Prosocial (Atkins et al., 2019) combines Acceptance & Commitment Therapy (ACT; S. Hayes et al., 2012) and Multi-Level Selection Theory (Wilson & Sober, 1994) with Nobel Laureate Elinor Ostrom’s Core Design Principles (CDPs) for effective group-level processes (Ostrom, 2012, 2015). Ostrom’s work was ground-breaking but, being primarily descriptive in nature, did not provide a full account of the processes and procedures required to implement the CDPs. The current paper outlines the theoretical underpinnings of Prosocial and offers guidelines for its application within educational communities, providing specific examples of the wide array of ways in which the approach can be applied by professionals such as educational psychologists (EPs) to bring about positive change at the systemic level.
The mechanics of anisotropic spring networks
Creators: name: Zhang, T.
name: Schwarz, J. M.
name: Das, Moumita
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We construct and analyze a model for a disordered linear spring network with anisotropy. The modeling is motivated by, for example, granular systems, nematic elastomers, and ultimately cytoskeletal networks exhibiting some underlying anisotropy. The model consists of a triangular lattice with two different bond occupation probabilities, $p_x$ and $p_y$, for the linear springs. We develop an effective medium theory (EMT) to describe the network elasticity as a function of $p_x$ and $p_y$. We find that the onset of rigidity in the EMT agrees with Maxwell constraint counting. We also find beyond linear behavior in the shear and bulk modulus as a function of occupation probability in the rigid phase for small strains, which differs from the isotropic case. We compare our EMT with numerical simulations to find rather good agreement. Finally, we discuss the implications of extending the reach of effective medium theory as well as draw connections with prior work on both anisotropic and isotropic spring networks.
Supplementary document for All-fiber GHz few-cycle pulse generation at 2 μm - 7173653.pdf
Creators: name: Liang, Zhaoheng
name: Pan, Minjie
name: Lin, Wei
name: Zhang, Nan
name: Wen, Junpeng
name: Chen, Xuewen
name: LING, LIN
name: Li, Zihan
name: Wei, Xiaoming
name: Yang, Zhongmin
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Numerical simulation and related discussions
title: Критерии диагностики вирусной пневмонии у детей при нормальной рентгенограмме
title: Diagnostic criteria for viral pneumonia In children with normal chest X-ray
Creators: name: Царькова, Софья Анатольевна
name: Абдуллаев, Александр Низаминович
name: Суровцева, Дарья Александровна
Publisher: name: Издательский центр СурГУ
Year: 2020

description: Цель – установить вероятность ассоциации пневмонии вирусной этиологии с отсутствием инфильтративных изменений при рентгенографии легких среди случаев рентгенонегативной пневмонии в клинической практике. Материал и методы. Проведен поиск вероятных критериев вирусной этиологии внебольничной пневмонии в базах данных PubMed и КиберЛенинка. Также проведено одномоментное исследование случаев рентгенонегативной пневмонии среди детей на основании анализа медицинской документации педиатрического отделения детской городской больницы г. Екатеринбурга. В исследовании были сформированы 2 группы: 20 детей с рентгенонегативной пневмонией (1,7 +/- 0,2 лет); 18 детей с рентгенопозитивной внебольничной пневмонией (2,3 +/- 0,2 лет). Результаты. На основании подсчета количества критериев пневмонии, не имеющей очага инфильтрации по данным рентгенографии, определен ряд достоверных признаков, характерных для вирусной этиологии внебольничной пневмонии: скудность данных при физикальном исследовании органов дыхания, отсутствие гнойной мокроты и выраженных провоспалительных изменений в анализах крови и непропорциональное увеличение ЧСС/ЧД. Предикторами заболевания служили анамнестические особенности: наличие гипотрофии, иммунодефицитных состояний и внутриутробного инфицирования у детей.
description: The study aims to establish the possible association of pneumonia of viral etiology with the absence of infiltrative changes in chest radiograph among cases of X-ray-negative pneumonia in clinical practice. Material and methods. The search for potential features of the viral etiology of community-acquired pneumonia in the PubMed and CyberLeninka databases is made. A simultaneous study of cases of X-ray-negative pneumonia among children based on the analysis of data from the pediatric department of the children’s city hospital in the city of Yekaterinburg is carried out. Two groups were formed: 20 children with X-ray-negative pneumonia (1.7 +/- 0.2 years), 18 children with a confirmatory X-ray of community-acquired pneumonia (2.3 +/- 0.2 years). Results. Based on the calculation of features for pneumonia that does not have an infiltrate according to radiography, the number of accurate signs characteristic of the viral etiology of community-acquired pneumonia was determined. These signs are the limited data on physical examination of the respiratory system, the absence of purulent sputum and evident pro-inflammatory changes in blood tests, and a disproportionate increase in heart rate or breathing rate. Warning signs of the disease were anamnestic features that are the presence of malnutrition, immunodeficiency, and intrauterine infection in children.
Supplementary document for Single-pixel phase imaging via complex-valued Zernike basis - 7171932.pdf
Creators: name: Lu, Yuxin
name: Zhao, wenjing
name: Zhai, Aiping
name: Liu, Nuo
name: Wang, Dong
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Single-pixel phase imaging via complex-valued Zernike basis: supplemental document
Introduzione
Creators: name: Conforti, Claudia
name: Belli, Gianluca
name: D’Amelio, Maria Grazia
name: Funis, Francesca
Publisher: name: Opus Incertum
Year: 2018

description: Wooden coffered ceilings attest to the recovery of antiquity and the search for luxury in Renaissance architecture, first in Florence, then in Rome. They appear in 15th century Italian architecture with their formal and constructive perfection: carved, sculpted, painted, enriched with xylographies and plasters, in soft wood or in papier-mâché. Coffered ceilings, clad with gold or in bright red and blue colours, are polymateric masterpieces, the result of the work of several artisans, of transverse technical knowledge and of different artistic styles. Their diffusion in Renaissance architecture is sudden and pervasive: in a few decades they characterize the new interiors of Florentine building, such as the church of San Lorenzo, the Magi Chapel and some other rooms in the palazzo Medici. Simultaneously, in Rome, coffered ceilings emulate and surpass their former glory, renewing the naves of ancient basilicas – San Marco and Santa Maria Maggiore – as well as the great halls of stately aristocratic and curial palaces. This monographic issue aims at documenting and analysing, through some case studies, the revival of wooden coffered ceilings in the 15th century and their successive fortune; the techniques and the artists who conceived and executed them; the types of wood species used; the literary and artistic sources providing descriptions and instructions concerning their construction.
description: Opus Incertum, Vol 3 (2017)
Disorder Effects in BCS-BEC Crossover Region of Attractive Hubbard Model
Creators: name: Kuchinskii, E. Z.
name: Kuleeva, N. A.
name: Sadovskii, M. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the disorder effects upon superconducting transition temperature T_c and the number of local pairs in attractive Hubbard model within the combined Nozieres - Schmitt-Rink and DMFT+Σapproximations. We analyze the wide range of attractive interaction U, from the weak coupling region, where instability of the normal phase and superconductivity are well described by BCS model, to the limit of strong coupling, where superconducting transition is determined by Bose--Einstein condensation of compact Cooper pairs, forming at temperatures much higher than superconducting transition temperature. It is shown that disorder can either suppress T_c in the weak coupling limit, or significantly enhance T_c in the case of strong coupling. However, in all cases we actually prove the validity of generalized Anderson theorem, so that all changes of T_c are related to change of the effective bandwidth due to disorder. Similarly, disorder effects on the number of local pairs are only due to these band-widening effects.
description: 5 pages, 4 figures
Поховання Чечеліївка 1/3 та проблема «майкопської присутності» в Україні
Creators: name: Ivanov, Mykyta
Publisher: name: Zenodo
Year: 2023
Subjects: Trypillia, Maikop, pottery, kurgan

description: The following slides present a finding of fine ware discovered within the kurgan burial Chechelivka 1/3. Tripillian attribution of the complex vs Maikop attribution is discussed.
I soffitti lignei dipinti del XIV e XV secolo nel mezzanino di Palazzo Vecchio: storia di un recupero
Creators: name: Pini, Serena
Publisher: name: Opus Incertum
Year: 2018

description: There are still some loose ends regarding the history of the construction and subsequent transformation of Palazzo Vecchio. This paper presents new information concerning one of the lesser-known floors of the building, the so-called Mezzanino, as a result of a series of unpublished considerations regarding the restoration work carried out by Alfredo Lensi between 1929 and 1932. It briefly retraces the history of the floor and the hypotheses concerning the modifications that may have been carried out by Michelozzo di Bartolomeo, as well as its various intended usages. The paper then describes 20th century interventions, focusing on the discovery and restoration of three painted platforms and the friezes and cornices below them which are now visible in the Mezzanino: the first two, in the Terrazzino and Marzocco rooms, have almost identical 14th century decorations, whereas the third, which dates back to the late 15th century, is located in the Gigli d’oro Hall. The documents and photographs related to the project show how the three ceilings and their respective decorations are original, although they were retouched during the restoration works. They also prove that the 15th century platform was transferred to the Gigli d'oro from the Marzocco, where it covered an earlier 14th century ceiling.
description: Opus Incertum, Vol 3 (2017)
Mimetic $F(R)$ gravity: inflation, dark energy and bounce
Creators: name: Nojiri, Shin'ichi
name: Odintsov, Sergei D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose the mimetic $F(R)$ theory and investigate the early-time and late-time acceleration in such theory. It is demonstrated that inflation consistent with observable data may be realized in such theory. The reconstruction of realistic $Λ$CDM era is also possible as well as the unification of early-time inflation with late-time acceleration or bounce universe. It is stressed that specific universe evolution is governed by mimetic $F(R)$ theory which is different from convenient $F(R)$ gravity. The corresponding examples are presented. Mimetic $F(R)$ gravity is generalized by the addition of the scalar potential in the formulation of convenient $F(R)$ gravity with specific Lagrange multiplier constraint. It is demonstrated that such theory may admit the arbitrary universe evolution via the corresponding choice of the scalar potential and/or function $F(R)$.
description: LaTeX 8 pages, extended version, new abstract
Recommendations for choosing an analysis method that controls Type I error for unbalanced cluster sample designs with Gaussian outcomes: J. L. JOHNSONET AL.
Creators: name: Muller, Keith E.
name: Glueck, Deborah H.
name: Murray, David M.
name: Kreidler, Sarah M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: We used theoretical and simulation-based approaches to study Type I error rates for one-stage and two-stage analytic methods for cluster-randomized designs. The one-stage approach uses the observed data as outcomes, and accounts for within cluster correlation using a general linear mixed model. The two-stage model uses the cluster specific means as the outcomes in a general linear univariate model. We demonstrate analytically that both one-stage and two-stage models achieve exact Type I error rates when cluster sizes are equal. With unbalanced data, an exact size α test does not exist and Type I error inflation may occur. Via simulation, we compare the Type I error rates for four one-stage and six two-stage hypothesis testing approaches for unbalanced data. With unbalanced data, the two-stage model, weighted by the inverse of the estimated theoretical variance of the cluster means, and with variance constrained to be positive, provided the best Type I error control for studies having at least 6 clusters per arm. The one-stage model with Kenward-Roger degrees of freedom and unconstrained variance performed well for studies having at least 14 clusters per arm. The popular analytic method of using a one-stage model with denominator degrees of freedom appropriate for balanced data performed poorly for small sample sizes and low intracluster correlation. Since small sample sizes and low intracluster correlation are common features of cluster-randomized trials, the Kenward-Roger method is the preferred one-stage approach.
D5.3 Predictive Maintenance Integrated with CMMS.
Creators: name: Ortega, Enric
name: Quintana, Antoni
name: Òscar Subirats
name: Enrich, Regina
name: Castro, José
Publisher: name: Zenodo
Year: 2023

description: This module will be developed to interconnect the predictive maintenance system with the system of automatic maintenance management (CMMS) of facilities used in COMSA. The improved CMMS will have automatic alarms linked to predictive mainte-nance developed. Previous to that COMS will determine the key operating parameters which are predictive of failure or malfunc-tion needed for corrective maintenance and interfacing with the automatic maintenance management (CMMS) while EUR will ad-dress the technical integration of the results of the algorithms of optimization and detection of failures into a maintenance manage-ment system. The module (and the integrated concept) will be tested in lab conditions with a collection of data sets, prior to its deployment in real conditions in WP6.
Discrete Family Symmetry from F-Theory GUTs
Creators: name: Karozas, Athanasios
name: King, Stephen F.
name: Leontaris, George K.
name: Meadowcroft, Andrew K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider realistic F-theory GUT models based on discrete family symmetries $A_4$ and $S_3$, combined with $SU(5)$ GUT, comparing our results to existing field theory models based on these groups. We provide an explicit calculation to support the emergence of the family symmetry from the discrete monodromies arising in F-theory. We work within the spectral cover picture where in the present context the discrete symmetries are associated to monodromies among the roots of a five degree polynomial and hence constitute a subgroup of the $S_5$ permutation symmetry. We focus on the cases of $A_4$ and $S_3$ subgroups, motivated by successful phenomenological models interpreting the fermion mass hierarchy and in particular the neutrino data. More precisely, we study the implications on the effective field theories by analysing the relevant discriminants and the topological properties of the polynomial coefficients, while we propose a discrete version of the doublet-triplet splitting mechanism.
description: 49 pages, 9 figures
Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation
Creators: name: Wronski, Ania
name: Prat, Aleix
name: Gupta, Piyush B.
name: Skibinski, Adam
name: Perou, Charles M.
name: Proia, Theresa
name: Phillips, Sarah
name: Shirley, Stephanie H.
name: Gill, Grace
name: Mazumdar, Sohini
name: Sedic, Maja
name: Kuperwasser, Charlotte
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: SummaryPerturbations in stem cell activity and differentiation can lead to developmental defects and cancer. We use an approach involving a quantitative model of cell-state transitions invitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, modulates mammary epithelial stem cell activity and differentiation invivo. In the absence of SLUG, stem cells fail to transition into basal progenitor cells, while existing basal progenitor cells undergo luminal differentiation; together, these changes result in abnormal mammary architecture and defects in tissue function. Furthermore, we show that in the absence of SLUG, mammary stem cell activity necessary for tissue regeneration and cancer initiation is lost. Mechanistically, SLUG regulates differentiation and cellular plasticity by recruiting the chromatin modifier lysine-specific demethylase 1 (LSD1) to promoters of lineage-specific genes to repress transcription. Together, these results demonstrate that SLUG plays a dual role in repressing luminal epithelial differentiation while unlocking stem cell transitions necessary for tumorigenesis.Highlights•SLUG promotes stem cell-state transitions necessary for tumorigenesis•Loss of SLUG in mice leads to luminal differentiation of basal/myoepithelial cells•Invitro quantitative modeling can accurately predict epithelial plasticity invivo•A SLUG/LSD1 complex epigenetically regulates mammary epithelial cell differentiationPerturbations in stem cell activity and differentiation can lead to developmental defects and cancer. Here, Kuperwasser, Gupta, and colleagues show that the transcription factor SLUG plays a dual role in repressing luminal epithelial differentiation while unlocking stem cell transitions necessary for tissue regeneration and tumorigenesis.
Il soffitto ligneo cassettonato della basilica di San Lorenzo a Firenze
Creators: name: Fedeli, Francesca
Publisher: name: Opus Incertum
Year: 2018

description: This paper, accompanied by an abundant graphic and photographic documentation, aims at examining the historical events related to the construction of the coffered ceiling of the basilica of San Lorenzo in Florence, as well as the techniques used during its execution. Since there had been as yet no systematic study of these works, the restoration carried out between 1994 and 1999 under the Superintendency for the Environmental and Architectural Heritage of the provinces of Florence, Pistoia and Prato provided an excellent opportunity for their study and understanding. The consultation of archival and photographic-documentary material regarding the restoration allowed to examine and understand the construction techniques used. Under their current ivory-white colouring, which dates from the 19th century, two other colours were found: one pale-blue, extended throughout the entire surface of the ceiling, derived from the 1739 restoration under the Electress of the Palatinate, and another from the 15th century which was found only in some panels. Based upon literary sources an attempt was made to determine the building phases of the ceiling, relating them to those regarding the entire structure of San Lorenzo; additionally, the structure of the ceiling itself was studied and compared to other wooden structures from that period.
description: Opus Incertum, Vol 3 (2017)
Experiment 2 (JOL): Metacognitive Judgements and Working Memory Precision
Creators: name: Krasnoff, Julia
name: Souza, Alessandra
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: We present participants sequences with 2,4 and 8 colored objects and they make predictions for the likelihood of retrieving the color of those objects in a final test. In one between-subject condition participants engage in an immediate test after making the JOL. The goal is to investigate what influences people's predictions of future recall.
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice
Creators: name: Bennett, Brian J.
name: Zhou, Xiaoying
name: Hartiala, Jaana
name: Crow, Amanda L.
name: Allayee, Hooman
name: Parks, Brian W.
name: Adams, Gregor B.
name: Barsky, Lora W.
name: Jain, Rajan
name: Eskin, Eleazar
name: Epstein, Jonathan A.
name: Lusis, Aldons J.
name: Ghazalpour, Anatole
name: Spindler, Tassja J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Prior efforts to identify regulators of hematopoietic stem cell physiology have relied mainly on candidate gene approaches with genetically modified mice. Here we used a genome-wide association study (GWAS) strategy with the hybrid mouse diversity panel to identify the genetic determinants of hematopoietic stem/progenitor cell (HSPC) frequency. Among 108 strains, we observed ∼120- to 300-fold variation in three HSPC populations. A GWAS analysis identified several loci that were significantly associated with HSPC frequency, including a locus on chromosome 5 harboring the homeodomain-only protein gene (Hopx). Hopx previously had been implicated in cardiac development but was not known to influence HSPC biology. Analysis of the HSPC pool in Hopx−/− mice demonstrated significantly reduced cell frequencies and impaired engraftment in competitive repopulation assays, thus providing functional validation of this positional candidate gene. These results demonstrate the power of GWAS in mice to identify genetic determinants of the hematopoietic system.
“Un sol di paradiso”. I soffitti all’antica di palazzo Medici a Firenze
Creators: name: Funis, Francesca
Publisher: name: Opus Incertum
Year: 2018

description: This paper clarifies the historical constructive aspects of two 15th century wooden ceilings of the Medici palace (later Riccardi): the ceiling of the great hall and that of the Magi chapel. An hitherto unknown documentation from the Archive of the Opera of Santa Maria del Fiore, establishes the dating of timber works in the building yard (January 1449 - February 1451), and explains the methods of supply, origins and quantities of the wood purchased by Cosimo the Elder for the palace. The two ceilings are among the first coffered ceilings carved the "ancient" way. Their novelty consists in the shape but also in the use of double composite beams to support the coffers: this technical device was so new in Florence at the period that it required the shipment of a wooden model of a beam (1451) from Ferrara. Finally, the study explains how the restoration and consolidation of the great hall ceiling throughout the centuries has completely transformed the original structure: the works carried out by the Riccardi family (1660) more than halved the size of the ceiling, and gave it a different pictorial decoration, now entirely removed after the recent pictorial restoration (1998) aimed at restoring the Fifteenth Century aspect to the ceiling.
description: Opus Incertum, Vol 3 (2017)
Is there evidence for a General Learning Monitoring Ability and is it related to Working Memory Capacity?
Creators: name: Krasnoff, Julia
name: Souza, Alessandra
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: A pre-registration of an online experiment that investigates whether there is evidence for a general learning monitoring ability and whether such an ability is related to working memory capacity.
Side population sorting separates subfractions of cycling and non-cycling intestinal stem cells
Creators: name: Seiler, Kristen M.
name: Henning, Susan J.
name: von Furstenberg, Richard J.
name: Winton, Douglas J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Isolation of quiescent intestinal stem cells (ISCs) has remained a challenge.By side population (SP) sorting we show cycling ISCs to be in the upper SP.The lower SP is non-cycling and has markers of the quiescent ISCs.In culture both upper and lower SP cells yield all 4 intestinal lineages.Evidence for a role of lower SP cells in repair of intestinal damage is discussed.We report here that side population (SP) sorting allows for the simultaneous isolation of two intestinal stem cell (ISC) subsets from wild-type (WT) mice which are phenotypically different and represent cycling and non-cycling pools of cells. Following 5-ethynyl-2′-deoxyuridine (EdU) injection, in the upper side population (USP) the percentage of EdU + was 36% showing this fraction to be highly proliferative. In the lower side population (LSP), only 0.4% of cells were EdU +, indicating this fraction to be predominantly non-cycling. Using Lgr5-EGFP mice, we show that Lgr5-EGFPhi cells, representing actively cycling ISCs, are essentially exclusive to the USP. In contrast, using histone 2B-YFP mice, SP analysis revealed YFP label retaining cells (LRCs) in both the USP and the LSP. Correspondingly, evaluation of the SP fractions for mRNA markers by qRT-PCR showed that the USP was enriched in transcripts associated with both quiescent and active ISCs. In contrast, the LSP expressed mRNA markers of quiescent ISCs while being de-enriched for those of the active ISC. Both the USP and LSP are capable of generating enteroids in culture which include the four intestinal lineages. We conclude that sorting of USP and LSP fractions represents a novel isolation of cycling and non-cycling ISCs from WT mice.Figure optionsDownload full-size imageDownload high-quality image (243 K)Download as PowerPoint slide
Hoffmann's conjecture for totally singular forms of prime degree
Creators: name: Scully, Stephen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Number Theory (math.NT)
subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics
subject: 11E04, 14E99, 15A03

description: One of the most significant discrete invariants of a quadratic form $ϕ$ over a field $k$ is its (full) splitting pattern, a finite sequence of integers which describes the possible isotropy behaviour of $ϕ$ under scalar extension to arbitrary overfields of $k$. A similarly important, but more accessible variant of this notion is that of the Knebusch splitting pattern of $ϕ$, which captures the isotropy behaviour of $ϕ$ as one passes over a certain prescribed tower of $k$-overfields. In this paper, we determine all possible values of this latter invariant in the case where $ϕ$ is totally singular. This includes an extension of Karpenko's theorem (formerly Hoffmann's conjecture) on the possible values of the first Witt index to the totally singular case. Contrary to the existing approaches to this problem (in the nonsingular case), our results are achieved by means of a new structural result on the higher anisotropic kernels of totally singular quadratic forms. Moreover, the methods used here readily generalise to give analogous results for arbitrary Fermat-type forms of degree $p$ over fields of characteristic $p>0$. Related problems concerning the Knebusch splitting of symmetric bilinear forms over fields of characteristic 2 and the full splitting of totally singular quadratic forms are also considered.
Aguti e bambole. Il palco ligneo della casa di Bartolomeo Scala a Firenze
Creators: name: Belli, Gianluca
Publisher: name: Opus Incertum
Year: 2018

description: The information on the construction of the Florentine house of Bartolomeo Scala, a building attributed with excellent reasons to Giuliano da Sangallo, has increased thanks to the discovery, three decades ago, of a book of accounts with a long series of expenses related to the works carried out from 1474 to 1477. The register has been linked to the work of Giuliano in the house, but almost certainly concerns an earlier phase, in which the existing buildings on the land plot purchased by Scala were reunited and adapted. In addition to providing names of masters and suppliers, the register contains many references to building materials, among which stand out many varieties of nails and a series of mirrors, used for the construction of the wooden “palco” of the hall. The analytical reading of this document allows us to hypothesize the form and characteristics of this extraordinary ceiling, perhaps decorated in such a way as to allude to the civic virtues of Bartolomeo Scala; in the text the position of the hall is also hypothesized, a room that has disappeared and has never been discussed before.
description: Opus Incertum, Vol 3 (2017)