cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Propeller thrust analysis using Prandtl's lifting line theory, a comparison between the experimental thrust and the thrust predicted by Prandtl' lifting line theory
Creators: name: Kesler, Steven R.
Publisher: name: University of Utah
Year: 2014
Subjects: Experiment
Lifting line
Prandtl
Propeller
Theory
Thrust

description: The lifting line theory was first developed by Prandtl and was used primarily on analysis of airplane wings. Though the theory is about one hundred years old, it is still used in the initial calculations to find the lift of a wing. The question that guided this thesis was, "How close does Prandtl's lifting line theory predict the thrust of a propeller?" In order to answer this question, an experiment was designed that measured the thrust of a propeller for different speeds. The measured thrust was compared to what the theory predicted. In order to do this experiment and analysis, a propeller needed to be used. A walnut wood ultralight propeller was chosen that had a 1.30 meter (51 inches) length from tip to tip. In this thesis, Prandtl's lifting line theory was modified to account for the different incoming velocity depending on the radial position of the airfoil. A modified equation was used to reflect these differences. A working code was developed based on this modified equation. A testing rig was built that allowed the propeller to be rotated at high speeds while measuring the thrust. During testing, the rotational speed of the propeller ranged from 13-43 rotations per second. The thrust from the propeller was measured at different speeds and ranged from 16-33 Newton's. The test data were then compared to the theoretical results obtained from the lifting line code. A plot in Chapter 5 (the results section) shows the theoretical vs. actual thrust for different rotational speeds. The theory over predicted the actual thrust of the propeller. Depending on the rotational speed, the error was: at low speeds 36%, at low to moderate speeds 84%, and at high speeds the error increased to 195%. Different reasons for these errors are discussed.
Passaliolla corticalis
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Passaliolla
Passaliolla corticalis

description: Passaliolla corticalis (H. W. Bates, 1887)
Saprosites corticalis H. W. Bates 1887a: 93 (Brazil)
Distribution. Suriname: Stebnicka 2000: 237, 2009a: 42. French Guiana: Stebnicka 2009a: 42; MHCN. Brazil: H. W. Bates 1887a: 93 (Amazons Ega [= Brazil Amazonas (Tefé)] - as Saprosites corticalis); A. Schmidt 1910b: 79 (as Saprosites corticalis), 1922b: 411 (as Saprosites corticalis); Blackwelder 1944: 216 (as Saprosites corticalis); Stebnicka 2000: 237, 2009a: 42. Venezuela: Stebnicka 2009a: 42. Other: Stebnicka 2000: 237 (Bolivia, Ecuador, Peru), 2009a: 42 (Bolivia, Ecuador, Peru).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 36, DOI: 10.5281/zenodo.3678492
Alteration of murine mammary tumor metastasis and growth by cytomegalovirus infection
Creators: name: Olsen, Gregg Arden
Publisher: name: University of Utah
Year: 2012
Subjects: Cellular, Viral, and Molecular Biology

description: Host resistance to the development of metastatic lesions is complex and involves both lymphocyte and macrophage functions. Studies in both humans and animals have suggested that cytomegalovirus infection may alter these components of the defense mechanism of the host. In the present study, an experimental model was developed to determine whether cytomegalovirus infection would affect host resistance to the establishment of metastatic tumor nodules in the lungs of C3H mice after intravenous inoculation of a single-cell suspension of mammary tumor cells. The number of tumor nodules in the lungs, the lungs-heart/body weight ratio, and the mean day of death were determined in control animals inoculated intravenously with 10^ mammary tumor cells and compared with groups of animals also receiving a sublethal intraperitoneal inoculum of murine cytomegalovirus (MCMV) (10^ plaque-forming units) either 3 days before, on the day of, or 10 or 13 days after tumor cell inoculation. The results suggest a biphasic effect of virus infection of tumor development in the lung. A preexisting or  concurrent MCMV infection suppressed tumor growth and prolonged life, while a MCMV infection later in tumorigenesis enhanced tumor growth and shortened survival. These data suggest that MCMV modulates host resistance to the development of metastatic tumor nodules and that this experimental model may be utilized to investigate further the relationship betv/een virus-induced alterations of host defense mechanisms and tumor growth.
Brief an [Johann III] Bernoulli
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1779

description: von [Jean Hyacinthe de] Magellan
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Brief an Johann III Bernoulli
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1773

description: von [Jean Hyacinthe de] Magellan
description: Mit roter Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Brief an [Johann III Bernoulli]
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1778

description: von [Jean Hyacinthe de] Magellan
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Regulation of ligand release and receptor signaling by the membrane-anchoring domains of epidermal growth factor receptor ligands
Creators: name: Dong, Jianying
Publisher: name: University of Utah
Year: 2012
Subjects: Metalloprotease

description: The epidermal growth factor receptor (EGFR) plays an important role in transducing extracellular signals into a variety of biological responses. Ligand binding initiates receptor signaling. To date, six ligands have been identified for the EGF receptor: EGF, TGF alpha, amphiregulin, HB-EGF, betacellulin, and epiregulin. All are initially synthesized as membrane-anchored precursor proteins and subsequently released through regulated proteolysis. This dissertation investigates the role of the membrane-anchoring domain of EGFR ligands in regulating ligand release and receptor signaling. Ligand release was found to be required for efficient activation of EGFR by some ligands, such as EGF and TGF alpha, suggesting that the membrane-anchoring domain spatially restricts ligand availability and receptor activation. Using a domain-swapping strategy, two engineered ligands were made with the membrane-anchoring domains of EGF and HB-EGF respectively. These two ligands showed distinct patterns of trafficking and secretion resembling those of EGF and HB-EGF. This indicates that the membrane-anchoring domains of EGFR ligands dictate their localization and release. In addition, the ligand anchored via the HB-EGF membrane-anchoring domain was able to activate EGFR without being released. Thus, the membrane-anchoring domains of EGFR ligands also modulate their ability to signal as soluble or membrane-bound forms. The conclusions from these studies suggest that different EGFR ligands may perform different
Additional file 3 of Semantic and cognitive tools to aid statistical science: replace confidence and significance by compatibility and surprise
Creators: name: Rafi, Zad
name: Greenland, Sander
Publisher: name: figshare
Year: 2020
Subjects: subject: Statistics
subject: FOS: Mathematics

description: Additional file 3: Figure S1. Relative likelihoods for a range of hazard ratios. A relative likelihood function that corresponds to Fig. 2, the P-value function. Also plotted is the 1/6.83 likelihood interval (LI), which corresponds to the 95% compatibility interval. Computed from results in Brown et al. [34]. MLR = Maximum-Likelihood Ratio. HR = 1 represents no association.
Saprosites Redtenbacher 1858
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Saprosites

description: SAPROSITES Redtenbacher, 1858
Saprosites Redtenbacher 1858: 436
Synopsis. Stebnicka 2001a (Neotropics)
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 36, DOI: 10.5281/zenodo.3678492
Brief an [Johann III Bernoulli]
Creators: name: Castillon, Jean François de
Publisher: name: [s.n.]
Year: 1776

description: von J[ean] [François] de Castillon
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Brief an [Johann III] Bernoulli
Creators: name: Magalhães, João Jacinto de
name: Castillon, Giovanni Francesco Mauro Melchiorre
Publisher: name: [s.n.]
Year: 1781

description: von [Jean Hyacinthe de] Magellan
description: Der Brief trägt auf dem zweiten Blatt ein schwarzes Wachssiegel.
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
The role of nerve growth factor in the regulation of collateral axon sprouting
Creators: name: Saffran, Bruce Nathan
Publisher: name: University of Utah
Year: 2012
Subjects: Neurology
Biochemistry

description: A fundamental question in neurobiology is to what extent the mammalian brain retains the ability to remodel neuronal connections throughout maturity. Although the mature brain is normally not permissive to extensive axonal growth, there are situations where the environment does become permissive to axonal remodeling. A current hypothesis to explain axonal remodeling suggests that the postsynaptic target and trophic signals derived therefrom contribute most to changes in axonal connectivity. Several authors have provided evidence that the signal eliciting such changes is the accumulation of trophic molecules, such as nerve growth factor (NGF), produced by a denervated target. One example of axonal remodeling within the mature mammalian brain is the collateral sprouting of uninjured sympathetic axons into the septal-denervated rat hippocampal formation. Considerable evidence supports the hypothesis that the accumulation of NGF within the hippocampal formation elicits sympathetic ingrowth. In this paper, I will review the evidence that trophic molecules are responsible for the initiation and maintenance of collateral sprouting phenomena in general, and the sympathohippocampal sprouting response in particular. I will then present two research reports that demonstrate that although intraventricular infusion of NGF fails to elicit sympathetic sprouting into the hippocampal formation, it dramatically increases the sympathetic innervation of the extracerebral vasculature. Furthermore, when NGF is infused at various times after sympathetic axons have been induced to grow into the brain by a medial septal lesion, intraventricular NGF infusion not only fails to enhance the sprouted projection but reduces the amount and delays the onset of such sprouting. I will then propose that changes in NGF levels, in the absence of injury, are sufficient to produce extensive remodeling of mature, sympathetic arbors; and that such remodeling may be based on competition between branches of the same neuron.
Brief an [Johann III Bernoulli]
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1777

description: von [Jean Hyacinthe de] Magellan
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Saprosites breviusculus Harold 1867
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Saprosites
Saprosites breviusculus

description: Saprosites breviusculus Harold, 1867
Saprosites breviusculus Harold 1867b: 81 (Brazil - LECTOTYPE)
Distribution. Guyana: Stebnicka 2001a: 233, 2009a: 44. Suriname: Stebnicka 2009a: 44; MHCN. Brazil: Harold 1867b: 81; A. Schmidt 1910b: 79, 1922b: 410; Blackwelder 1944: 216; Stebnicka 2001a: 233 (designation LECTOTYPE Saprosites breviusculus), 2009a: 44. Venezuela: Stebnicka 2001a: 233, 2009a: 44. Other: A. Schmidt 1910b: 79 (Argentina), 1922b: 410 (Argentina); Blackwelder 1944: 216 (Argentina); Stebnicka 2001a: 233 (Argentina, Bolivia, Colombia, Paraguay), 2009a: 44 (Argentina, Bolivia, Colombia, Paraguay).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 36, DOI: 10.5281/zenodo.3678492
Brief an [Johann III] Bernoulli
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1776

description: Das zweite Blatt ist am Rand beschädigt.
description: von [Jean Hyacinthe de] Magellan
description: Mit Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Additional file 3 of Do the human gut metagenomic species possess the minimal set of core functionalities necessary for life?
Creators: name: Soverini, Matteo
name: Rampelli, Simone
name: Turroni, Silvia
name: Brigidi, Patrizia
name: Biagi, Elena
name: Candela, Marco
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3. Pie charts representing the phyla distribution in the two cohorts of genomes analyzed (A for NCBI genomes, B for UMGS).
DNA repair systems and cellular responses to DNA damage
Creators: name: Hinz, John Michael
Publisher: name: University of Utah
Year: 2012
Subjects: Molecular Biology
Cellular Biology

description: Within the context of a multicellular organism, accumulation of genetic mutations can lead to tumor formation. In order to avoid such deleterious events, each cell is equipped with a series of DNA damage sensors and repair systems to deal with the DNA lesions that can lead to such mutations. Joined to these repair systems are additional cellular responses, such as cell cycle arrest, providing the cell time for repair, or if need be, apoptosis, removing a cell from the population if the repair systems are not sufficient to deal with the DNA damage. The deleterious effects of deficiencies in components of the repair and cell response pathways are evident in the human diseases associated with inherited and spontaneous mutations in genes encoding these factors. This dissertation attempts to elucidate the specific roles of certain components of the DNA mismatch repair (MMR) and DNA double strand break (DSB) repair systems. In addition, we examined the link between their role in repair and other cellular responses to DNA damage. Employing a CHO model system, the role of mammalian MSH3, with respect to its function in mismatch repair, was studied. In agreement with studies of the human homolog, and the lack of disease associated with its mutation, we found no consistent link between the loss of MSH3 and the common cellular phenotypes associated with MMR deficiency. The MMR deficient HCT116 colon tumor cell line demonstrates the characteristics of a NMR deficient cell line, presumably due to the specific deficiency of the MMR protein hMLH1. Employing an inducible hMLH1 expression system, we were able to correct the MMR deficiency phenotype of this tumor line and, interestingly, only a small amount of hMLH1 expression was necessary for complementation. Finally, we studied the role of the Rad51 paralog XRCC3 in the homologous recombination associated DSB repair system. Employing a CHO model system, we found that despite the expected increase in sensitivity to camptothecin, a DNA double-strand break inducing agent, the XRCC3 deficient cell line irs1SF had a reduced apoptotic response. This suggests a link between the processes of homologous recombination and induction of apoptosis.
Atomic frontiers: how the bomb is transforming the literatures of the American West
Creators: name: Reynolds, Dynette Ivie
Publisher: name: University of Utah
Year: 2015
Subjects: American west
Atomic bomb
Downwinders
Eco-literature
Nuclearism
Nuclear studies

description: The cultural interaction between nuclear technology and the American West was a two-way process. On one side, an elite brotherhood of scientists and engineers at Los Alamos incorporated the romance of the frontier into the nation's atomic origin story. On the other side, the mythical construct we call "the West" mutated and matured due to its entanglement with the nuclear cycle. Only recently has it become clear that the engineer left an indelible mark on the American West equal to or even greater than that left by the cowboy. However, the engineer and the cowboy were always twin figures in the western imagination, even if the engineer usually lurked in the cowboy's shadow. The links forged between these two symbols early in the twentieth century were deliberately co-opted into the national atomic story after the war. In response, a variety of western atomic discourses began to emerge that both resisted and interacted with national narratives. As nuclearism wrote itself into the West, the stories westerners tell about themselves and their history started to change. Although the focus of this research is on the atomic literatures and discourses of the West-including fiction, memoir, poetry, drama, and nature writing-this is a multidisciplinary project that incorporates an extensive amount of history as well as a bit of scientific theory in order to more fully explore how nuclearism contributed to the changing cultural constructions of wilderness and technology in the twentieth-century American West.
Brief an [Johann III Bernoulli]
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1778

description: von üJean Hyacinthe de] Magellan
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Does the technique of administering DPT vaccine affect the frequency of local reactions in immunizations?
Creators: name: Richardson, Faye
Publisher: name: University of Utah
Year: 2012
Subjects: Adverse Effects

description: Most research regarding adverse reactions to diphtheria, pertussis and tetanus (DPT) immunizations has focused on severe systemic reactions.  Little information is available relating to the cause, frequency of severity of local reactions (redness, swelling, pain) that occur in the majority of DPT recipients.  This study determined that the method of injecting the DPT vaccine intramuscularly decreased the frequency of local reactions.  Sixty-eight children receiving their third DPT immunization were enrolled in this single-blind, controlled study.  The results indicated that local reaction were significantly reduced (p ? .10) when the DPT vaccine was administered by the z-track method of intramuscular injection with an air bolus following the vaccine using a dry, sterile 1" needle, as compared with other standard intramuscular techniques.
Triplex-forming branched obligonucleotides: sythesis and interactions with ribo- and deoxyribo-oligonucleotides
Creators: name: Joglekar, Seema P.
Publisher: name: University of Utah
Year: 2012
Subjects: Deosyribo-oligonucleotides
Ribo-olgonucleotides
Triplex

description: The goal of this thesis project was to design a branched oligodeoxynucleotide (odn) using novel synthetic approaches that can form stable triplex with target single stranded DNA or RNA. This triplex approach may lead toward a potential antisense construct that will target mRNA sequences.  The project is based upon the previous observation that when a single 2'-O-modified adenosine is incorporated within a DNA strand and that strand is subsequently used to form either DNA:DNA or DNA:RNA duplex, the aromatic substituent of the modified adenosine lies within the major groove of the duplex. Therefore, logically, the extension of this substituent into an oligonucleotide sequence may result in alignment of the oligonucleotide along the major groove of a target duplex to form a triplex.  Therefore, synthesis of 2'-O-(thymidin-5-yl)adenosme ( 16 ) was accomplished. The branched odn was created by incorporating 16 into a purine rich sequence and then extending the thymidine substituent into a pyrimidine rich sequence. This branched odn was designed to allow the purine sequence to form a duplex with a single-stranded pyrimidine target and then to have the pyrimidine branch subsequently form a triplex by aligning within the major groove of the duplex. Previous results in this laboratory and preliminary molecular modeling studies indicated that the methylene linker between the 2'-O- of adenosine (of 16 ) and the C-5 of pyrimidine would be sufficient for introduction of the branch into major groove.  Different sequences of branched odns were designed and triplex formation with the targets was evaluated using UV-melting, gel electrophoresis, molecular modeling and CD spectroscopy.  The results showed that the branched odns were effective in forming stable triplexes with DNA and RNA targets. The branched odns provided a three order of magnitude increase in the association rate of the triplex as compared to unmodified triplexes. The stabilization was effective when nucleoside 16 was incorporated at the 5' or 3' terminal of the branched odns. However, when the modified adenosine was introduced internally, the constraint at the branch point resulted in poor stabilization of the complex.  The branched odn model explored in this thesis contributed to the understanding of some of the parameters involved in formation of stable triplexes by branched odns with single stranded DNA and RNA targets.
Additional file 1 of Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials
Creators: name: Husain, Mansoor
name: Bain, Stephen C.
name: Holst, Anders Gaarsdal
name: Mark, Thomas
name: Rasmussen, Søren
name: Lingvay, Ildiko
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy

description: Additional file 1: Table S1. Summary of LEADER model, including full details of the baseline variables considered in the model. Data are based on the full analysis set. Individual HRs for stroke, smoking status, eGFR and LDL-C are not presented, as these were influenced by other baseline parameters. bpm, beats per minute; CI, confidence interval; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; HR, hazard ratio; LDL-C, low-density lipoprotein cholesterol; MI, myocardial infarction; NYHA, New York Heart Association; SBP, systolic blood pressure; SE, standard error.
A microfluidic in vitro model of the blood-brain barrier
Creators: name: Booth, Ross Hunter
Publisher: name: University of Utah
Year: 2015
Subjects: Blood-brain barrier
MEMS
Microfluidic

description: The blood-brain barrier (BBB) limits entry of most molecules into the brain and complicates the development of brain-targeting compounds, necessitating novel BBB models. This dissertation describes the first microfluidic BBB model allowing the study of BBB properties in relation to various chemical compounds by enabling tunable wall shear stress (WSS) via dynamic fluid flow, cell-cell interaction through a thin co-culture membrane, time-dependent delivery of test compounds, and integration of sensors into the system, resulting in significant reduction of reagents and cells required and shorter cell seeding time. Use of parallel channels first enabled simultaneous monitoring of multiple cell populations under a wide range (~x15) of WSS. The microfluidic model formed the BBB by incorporating brain endothelial (b.End3) and glial (C6/C8D1A) cells at the intersection of two crossing microchannels, respectively representing luminal and abluminal sides, fabricated in a transparent polydimethylsiloxane (PDMS) substrate utilizing high-precision soft lithography techniques. The utilized cells were adopted from immortalized cells for high consistency over repeated passages and pure and proliferative culture. The developed microfluidic BBB model was validated by (1) expression of tight junction protein ZO-1 and glial protein GFAP by fluorescence imaging, and P-gp activity by Calcein AM, confirming key BBB proteins; (2) high trans-endothelial electrical resistance (TEER) of co-cultures exceeding 250Ωcm2 confirming sufficiently contiguous cell layer formation; (3) chemically-induced barrier modulation, with transient TEER loss by 150μM histamine (~50% for 8-15min), and increase in permeability at elevated pH (10.0); (4) size-dependent (668-70,000Da) compound permeability mimicking in vivo trends; and (5) highly linear correlation (R2>0.85) of clearance rates of seven selected neural drugs with in vivo brain/plasma ratios. We demonstrated the effects of WSS (0-86dyn/cm2) on bEnd.3 properties under increasing WSS, including increase in (6) TEER, (7) cell re-alignment toward flow direction, and (8) protein expression of ZO-1/P-gp, and (9) decrease in tracer permeability. The developed in vitro microfluidic BBB model provides distinct advantages for monitoring and modulating barrier functions and prediction of compound permeability. Thus, it would provide an innovative platform to study mechanisms and pathology of barrier function as well as to assess novel pharmaceuticals early in development for their BBB clearance capabilities.
Brief an [Johann III] Bernoulli
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1774

description: von [Jean Hyacinthe de] Magellan
description: Mit Spuren von einer roten Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
description: Daten zur Beantwortung astronomischer Fragen von Jean Hyacinthe de Magellan
Brief an [Johann III] Bernoulli
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1782

description: von [Jean Hyacinthe de] Magellan
description: Der Brief trägt auf der letzten Seite ein schwarzes Wachssiegel.
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Effect of cortisol and deoxycorticosterone acetate on brain amino acid and electrolyte metabolism
Creators: name: Vernadakis, Antonia
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Physiology
subject: FOS: Biological sciences

description: Numerous studies have been carried out on the adrenocortical steroids during the last fifteen years.  The effects of adrenocortical steroids on carbohydrate, fat, electrolyte and protein metabolism of various tissues and organs, and the specificity of these hormonal actions continue to be investigated. The adrenocortical steroids have been found to have important actions on the central nervous systems they can alter the motor excitability of the brain (Woodbury and Sayers,1950; Woodbury, 1952).  In rats, deoxycorticosterone increases the threshold for electrical excitability, whereas cortisone and hydrocortisone cause hyperexcitability. The influence of adrenocortical steroids on brain excitability can be related to their effects on electrolyte metabolism,, Desocycorticosterone stimulates active transport of Na out of brain cells (Woodbury et al., 1957) and by this process decreases brain excitability. Cortisone^ in contrast,, inhibits active Na transport and thereby causes an increase in both intracellular brain Na concentration and brain excitability.  The present study is designed to contribute further knowledge concerning the effects of adrenocortical steroids on brain function and metabolism. The study of the effect of adrenocortical steroids on brain amino acids arises from the observations that? (a) glutamic acid and gluta-mine are implicated in transport of K by brain cells (Terner et al., 1950), (b) adrenocortical steroids are known to alter profoundly the amino acid composition of various tissues (Dubreuil and Timiras, 1953),  and (c) ?-aminobutyric acid5 a metabolic product of glutamic acid5 has recently been suggested to have an inhibitory effect on brain excitability (Elliott and Florey, 1956).  The following investigations were carried outs a) effect of age on brain amino acid concentration! b) effect of cortisone and deoxycorticosterone on brain amino acid and electrolyte concentrationsj and c) effect of adrenalectomy on brain amino acid and electrolyte concentrations,
Brief an [Johann III] Bernoulli
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1774

description: von [Jean Hyacinthe de] Magellan
description: Mit Spuren von einer roten Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Additional file 2 of Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials
Creators: name: Husain, Mansoor
name: Bain, Stephen C.
name: Holst, Anders Gaarsdal
name: Mark, Thomas
name: Rasmussen, Søren
name: Lingvay, Ildiko
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy

description: Additional file 2: Table S2. Summary of risk models for semaglutide (including model selection) for pooled SUSTAIN and PIONEER data. AIC, Akaike Information Criterion; SBC, Schwarz Bayesian Information Criterion.
Relationship between leadership styles and faculty job satisfaction in Taiwan
Creators: name: Chen, Hsiu-Chin
Publisher: name: University of Utah
Year: 2012
Subjects: Taiwan

description: This was a descriptive, correlational, and cross-sectional study using self-administered questionnaires. The main purposes of this study were to examine the nursing faculty's perceptions of nursing deans' and directors' leadership styles, and to understand how well the perceptions relate to faculty job satisfaction levels. The transformational leadership theory and a direct-effects model supported the research framework of this study. A random sampling technique was employed to collect data from 18 schools with nursing programs. A total of 400 questionnaires were mailed directly to the selected faculty members at the school address. A number of 286 questionnaires were returned, representing a 72.96% response rate. Findings indicated that Taiwanese nursing deans and directors tend to display transformational leadership more frequently than the transactional leadership and the laissez-faire in their workplace. In addition, Taiwanese nursing faculty members reported moderate levels of satisfaction in their jobs. Regardless of each school's organizational characteristics, nursing deans and directors performed transformational leadership more frequently than the transactional leadership and the laissez-faire. The contingent reward, passive management-by-exception, and individualized consideration leadership styles of nursing deans and directors were significant predictors of nursing faculty job satisfaction in Taiwan. This study helps pave a path for Taiwan's researchers to understand the importance of setting up a leadership training program for nursing leaders.
Saprosites sulcatus Harold 1869
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Saprosites
Saprosites sulcatus

description: Saprosites sulcatus Harold, 1869
Saprosites sulcatus Harold 1869a: 102 (Brazil - LECTOTYPE)
Distribution. Suriname: MHCN - NEW COUNTRY RECORD (Suriname, Sipaliwini, Raleighvallen NP, western bank Coppename. 28-III-1998. A. J. Hielkema. Under bark.); NZCS. Brazil: Harold 1869a: 102; A. Schmidt 1910b: 80, 1922b: 407; Blackwelder 1944: 216; Stebnicka 2001a: 224 (designation LECTOTYPE Saprosites sulcatus), 2009a: 51. Other: A. Schmidt 1922b: 407 (Bolivia); Stebnicka 2001a: 224 (Argentina, Bolivia, Paraguay, Peru), 2009a: 51 (Argentina, Colombia, Peru).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 36, DOI: 10.5281/zenodo.3678492
Brief an [Johann III Bernoulli]
Creators: name: Magalhães, João Jacinto de
name: Dollond, Pierre
Publisher: name: [s.n.]
Year: 1782

description: von [Jean Hyacinthe de] Magellan
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
description: Bl. 85: Druck eines Briefes von Magellan an einen Freund in Paris (Extrait d'une lettre à un de ses amis de Paris)
description: Bl. 87: Gedruckter Katalog mit Instrumenten von Dollond (Un Catalogue des Instruments Optiques, Mathematiques et Philosophiques par P[ierre] Dollond)
Saprosites Redtenbacher 1858
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Saprosites

description: Saprosites sp.
Distribution. French Guiana: Brûlé et al. 2014: 147.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 37, DOI: 10.5281/zenodo.3678492
Collagen macromolecular drug delivery systems
Creators: name: Gilbert, Donna Lynn
Publisher: name: University of Utah
Year: 2012
Subjects: Drug Delivery Systems
Polymers
Pharmacy

description: Controlled release systems have been successfully applied for the delivery of low molecular weight compounds. The application of these systems to high molecular weight compounds has been more difficult due to their molecular size and the problems associated with diffusion of macromolecules through membranes. The objective of this dissertation was to examine collagen for use as a macromolecular drug delivery system by determining the mechanism of release through a matrix.  Collagen membranes varying in porosity, crosslinking density, structure and crosslinker were fabricated. Collagen characterized by infrared spectroscopy and solution viscosity was determined to be pure and native. The collagen membranes were determined to possess native vs. non-native quaternary structure and porous vs. dense aggregate membranes by electron microscopy.  Permeation studies determined that the proteins diffused by a pore mechanism, a consequence of the linear relationship between diffusion coefficients and the protein radius or membrane hydration. The diffusion coefficients were higher for membranes with porous fibril structure, low crosslinking density, membranes crosslinked with a hydrophilic crosslinker (polyglycerol polyglycidyl ether) and non-native quaternary structure.  Collagen monolithic devices containing a model macromolecule (inulin) were fabricated. In vitro release rates were found to be linear with respect to t1/2  and were affected by crossl inking density, crosslinker and structure. The biodegradation of the collagen matrix was also examined. Proteolytic enzymes did not degrade the collagen devices, whereas, the degradation rate with collagenase was dependent on collagen structure, crosslinker, crosslinking density and enzyme concentration.  in vivo biocompatibility, degradation and   -inulin release rates were evaluated subcutaneously in rats. Three weeks implantation of the collagen discs did not induce severe cellular responses. Dacron® induced a stronger fibroblast response but fewer inflammatory cells as compared to the collagen discs. No significant degradation of the collagen discs occurred within three weeks, in vivo release of 14C-inulin from collagen monolithic devices was diffusion controlled.  This dissertation demonstrated the feasibility of obtaining macromolecular release from collagen matrices. Important parameters regulating the release include porosity, structure, hydrophilicity of crosslinker and crosslinking density. The benefits of using collagen as a controlled release matrix include its biocompatibil ity and in vivo degradation.
Additional file 4 of Do the human gut metagenomic species possess the minimal set of core functionalities necessary for life?
Creators: name: Soverini, Matteo
name: Rampelli, Simone
name: Turroni, Silvia
name: Brigidi, Patrizia
name: Biagi, Elena
name: Candela, Marco
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 4. Boxplots representing the percentage of CMF genes covered by different groups of genomes: UMGS having a CheckM completeness score higher or equal than 90% (dark red), UMGS having a CheckM completeness score lower than 90% (red) and NCBI isolates genomes (skyblue).
Tanyana Stebnicka 2006
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Aphodiidae
Tanyana

description: TANYANA Stebnicka, 2006
Tanyana Stebnicka 2006b: 183
= Taenia Stebnicka 2003d: 355 - (nom. praeoc.), nec Taenia Linnaeus 1758: 819 (Platyhelminthes) - Stebnicka 2006b: 183 (syn. nov.)
Synopsis. Stebnicka 2003d
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 37, DOI: 10.5281/zenodo.3678492
Differences in swallowing duration for patients with xerostomia of four different etiologies and normal controls
Creators: name: Erickson, Lea Ella
Publisher: name: University of Utah
Year: 2012

description: Xerosomia contributes to an increased caries rate, mucositis, candidiasis, decreased prosthesis retention, diminished gestation, difficulty with speech, and dysphagia.  An extended duration of swallowing time, as a measure of swallowing dysfunction, has been associated with dry mouth in general and with Sjögren's syndrome specifically.  No difference in swallowing duration was demonstrated in a study of healthy volunteers across a wide rage of salivary flow rates.  This study further investigated the relationship between diminished salivary flow and swallow time.  A sample of 123 patients with hyposalivation of four difference etiologies (Sjögren's syndrome, radiation, sicca, and idiopathic), plus 35 normal controls, was included in the study.  Parotid flow rates and submandibular-sublingual flows rates for both stimulated and unstimulated saliva were measured and recorded.  The duration of the oropharyngeal swallow was measured by ultrasound imaging from the initiation of the swallow to the completion of the movement of the hyoid from rest position to maximal anterior and superior position and back to rest for three consecutive dry swallows and for three wet swallows were used for statistical analysis.  A correlation of little strength (r=.20 to -28), but differing from zero at a statistically significant level, was demonstrated between the salivary flow rate scores and the duration of the swallow times for the average of dry swallows (except the submandibular-sublingual flow score) and the average of we swallows.  The duration of the oropharyngeal phase of the swallow differed significantly between each diagnostic group (Sjögren's syndrome, radiation, indiopathic, and sicca) and the normal controls for one to three of the three swallowing measurers used.  Differences were demonstrated for all three swallowing measures for Sjögren's group.  The duration of the oropharyngeal phase of the swallow differed significantly between the quartile of individuals with the lowest salivary flow scores and that with the highest for the first dry swallow and the average of the wet swallows (p<0.04).  The relationship between salivary flow and swallowing function in a complex interaction not well understood.  A more complete understanding of the role of salivary flow in dysphagia will promote the designing of interventions to diminish the impact on nutrition quality of life.
Effects of special supplemental nutrition program for women, infants, and children (WIC) participtation on household food availability
Creators: name: Brewer, Cameron Michael
Publisher: name: University of Utah
Year: 2014
Subjects: Household food availability
WIC

description: Public health messages have focused on the health benefits of consuming more fruits and vegetables. The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a needs-based program that offers nutrition education and a food supplement or voucher. This study assesses the effect that WIC participation has on availability of healthy food. Additionally, this study accounts for potential nonrandom selection bias into WIC by employing techniques that address self-selection bias. The data were drawn from the National Health and Nutrition Examination Survey (NHANES) 2007-10 Consumer Behavior Survey. Results from switching regression equations reveal that WIC participation is negatively associated with fruit and dark leafy green vegetable availability at home. More research needs to be conducted on the effects of WIC participation on household food availability.
Brief an [Johann III Bernoulli]
Creators: name: Castillon, Giovanni Francesco Mauro Melchiorre
Publisher: name: [s.n.]
Year: 1780

description: von J[ean] [François] de Castillon
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Physician information network
Creators: name: Davidson, Marcel G.
Publisher: name: University of Utah
Year: 2012
Subjects: Diagnosis, Computer-Assisted
Artificial Intelligence

description: A computer network was begun in June 1985 which extended the facilities of the Health Evaluation through Logic Processing (HELP) system from its base at the Latter-day Saint (LDS) Hospital, Salt Lake City, Utah, to offices of some members of the hospital's medical staff.  Through the use of personal computers (PCs), data communication software and hardware, and the standard telephone network, the physicians and their staff were able to run HELP system laboratory, demographic, and other medical information programs directly from their offices or homes.  A security system was installed a part of the network to prevent intrusion by unauthorized users and to monitor network usage by registered users.  Analysis of network usage and security was performed during an initial 9-month study period, from June 1985 to February 1986, and during a 2-month follow up period in October and November 1986.  Usage patterns of network participants corresponded to standard office hours.  Peak usage occurred daily between 10:00 and 11:00 A.M., and weekly on Wednesdays.  The number of network participants never exceeded 13; however, use of the network facilities by registered users during the follow up period was more than double that of the initial study period.  Usage patterns varied greatly between individual uses (0 to 92.5 patient information reviews per month).  There was no overt intrusion by outsiders.  User restricted at least 81% of their reviews to patients for who they were attending, consulting, or affiliated physicians.  More complete record of physicians probably would have revealed an even higher level of confidentiality.  Users indicated that the network's major information review programs were useful to them, and that participation in the network increased their professional productivity.  While over 100 physicians had network facilities available to them, the network was probably use only by a small subset of these physicians.  This might have been due to three factors:  (1) physicians' lack of knowledge of the network; (2) the usefulness of the HELP system features to only a subset of the hospital's medical staff; and (3) physicians' inexperience and reluctance in dealing with computers.  By making its features better meet the need of the individual physician, participation in the physician information network may improve.
Brief an [Johann III Bernoulli]
Creators: name: Castillon, Giovanni Francesco Mauro Melchiorre
Publisher: name: [s.n.]
Year: 1777

description: von J[ean] [François] de Castillon
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Engineering factors relating to the utilization of the cannel coals of southern Utah
Creators: name: Jacobsen, Samuel Clark. Carter
Publisher: name: University of Utah
Year: 2012
Subjects: Cannel coal
Coal, Utah

description: The cooperative investigations of the State of Utah with the Federal Government, during the years 1919-1924, proved that Utah contains a number of very important bodies of carbonaceous materials offering excellent opportunities for producing desirable new solid fuels, oil products and gas, and thereby add new wealth to the State. Published data  by the investigators are comprehensive, but it is probable that the commercial significance of these researches have not as yet been fully appreciated by the Utah public, otherwise commercial uses of the results of these investigations would undoubtedly have been applied.
Brief an [Johann III Bernoulli]
Creators: name: Magalhães, João Jacinto de
Publisher: name: [s.n.]
Year: 1776

description: von [Jean Hyacinthe de] Magellan
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire Oktober 2015 Andrietta Wahl
Comment faisait-on jusqu’aux années 1980 avant l’ordinateur personnel ? Des trous, des petits trous
Creators: name: REY, Jean-Loup
Publisher: name: MTSI
Year: 2022

description: Les ordinateurs pour les chercheurs de terrain ne sont apparus que dans les années 1980. Auparavant, on se servait des fiches perforées que les plus anciens connaissent. Nous ne parlerons que des fiches (pré)perforées qui ont apporté un progrès net par rapport aux registres de tableaux et de colonnes. How did we do until the 1980s before the personal computer? Holes, small holes Computers for field researchers only appeared in the 1980s. Prior to that, punched cards were used, with which older people are familiar. We will only talk about the (pre-)punched cards, which were a clear improvement on the table and column registers.
description: MTSI, Vol. 2 No 3 (2022): MTSI-Revue