cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CD82 controls CpG-dependent TLR9 signaling.
Creators: name: Khan, Nida S
name: Lukason, Daniel P
name: Feliu, Marianela
name: Ward, Rebecca A
name: Lord, Allison K
name: Reedy, Jennifer L
name: Ramirez-Ortiz, Zaida G
name: Tam, Jenny M
name: Kasperkovitz, Pia V
name: Negoro, Paige E
name: Vyas, Tammy D
name: Xu, Shuying
name: Brinkmann, Melanie M
name: Acharaya, Mridu
name: Artavanis-Tsakonas, Katerina
name: Frickel, Eva-Maria
name: Becker, Christine E
name: Dagher, Zeina
name: Kim, You-Me
name: Latz, Eicke
name: Ploegh, Hidde L
name: Mansour, Michael K
name: Miranti, Cindy K
name: Levitz, Stuart M
name: Vyas, Jatin M
Publisher: name: The Francis Crick Institute
Year: 2021
Subjects: classificationCode: Model organisms
subject: Model organisms
classificationCode: Infectious Disease
subject: Infectious Disease
classificationCode: Immunology
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: Cell Biology
subject: Cell Biology

description: The tetraspanin CD82 is a potent suppressor of tumor metastasis and regulates several processes including signal transduction, cell adhesion, motility, and aggregation. However, the mechanisms by which CD82 participates in innate immunity are unknown. We report that CD82 is a key regulator of TLR9 trafficking and signaling. TLR9 recognizes unmethylated cytosine-phosphate-guanine (CpG) motifs present in viral, bacterial, and fungal DNA. We demonstrate that TLR9 and CD82 associate in macrophages, which occurs in the endoplasmic reticulum (ER) and post-ER. Moreover, CD82 is essential for TLR9-dependent myddosome formation in response to CpG stimulation. Finally, CD82 modulates TLR9-dependent NF-κB nuclear translocation, which is critical for inflammatory cytokine production. To our knowledge, this is the first time a tetraspanin has been implicated as a key regulator of TLR signaling. Collectively, our study demonstrates that CD82 is a specific regulator of TLR9 signaling, which may be critical in cancer immunotherapy approaches and coordinating the innate immune response to pathogens.-Khan, N. S., Lukason, D. P., Feliu, M., Ward, R. A., Lord, A. K., Reedy, J. L., Ramirez-Ortiz, Z. G., Tam, J. M., Kasperkovitz, P. V., Negoro, P. E., Vyas, T. D., Xu, S., Brinkmann, M. M., Acharaya, M., Artavanis-Tsakonas, K., Frickel, E.-M., Becker, C. E., Dagher, Z., Kim, Y.-M., Latz, E., Ploegh, H. L., Mansour, M. K., Miranti, C. K., Levitz, S. M., Vyas, J. M. CD82 controls CpG-dependent TLR9 signaling.
การศึกษาลักษณะการให้เหตุผลทางการอนุมานเชิงสถิติ ของนักศึกษาระดับปริญญาตรี: กรณีศึกษามหาวิทยาลัยราชภัฏมหาสารคาม ประเทศไทย
Creators: name: รามนรี นนทภา
Publisher: name: Facilty of Education Rajabhat Maha Sarakham University
Year: 2563
Subjects: การให้เหตุผลทางสถิติ
ลักษณะ
ลักษณะการให้เหตุผล

description: Journal of Education, 17, 3, 27-40
The Effects of Unemployment Insurance on Labor Supply and Search Outcomes
Creators: name: Wachter, Till M. Von
name: Bender, Stefan
Publisher: name: Columbia University
Year: 2009
Subjects: Labor economics

description: This paper evaluates the impact of large changes in the duration of unemployment insurance (UI) in different economic environments on labor supply, job matches, and search behavior. We show that differences in eligibility thresholds by exact age give rise to a valid regression discontinuity design, which we implement using administrative data on the universe of new unemployment spells and career histories over twenty years from Germany. We find that increases in UI have small to modest effects on non-employment rates, a result robust over the business cycle and across demographic groups. Thus, large expansions in UI during recessions do not lead to lasting increases in unemployment duration, nor can they explain differences in unemployment durations across countries. We do not find any effect of increased UI duration on average job quality, but show that the mean potentially confounds differential effects on job search across the distribution of UI duration. However, it appears that for a majority of UI beneficiaries increases in UI duration may lead to small declines in wages.
Very Light Axigluons and the Top Asymmetry
Creators: name: Krnjaic, Gordan Z.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We show that very light (50 - 90 GeV) axigluons with flavor-universal couplings of order g_{s}/3 may explain the anomalous top forward-backward asymmetry reported by both CDF and D0 collaborations. The model is naturally consistent with the observed t \bar t invariant mass distribution and evades bounds from light Higgs searches, LEP event shapes, and hadronic observables at the Z pole. Very light axigluons can appear as resonances in multijet events, but searches require sensitivity to masses below current limits.
description: 10 pages, 5 figures, references added, discussion of constraints expanded, general conclusions unchanged
Presynaptic modulation of a central cholinergic synapse by serotonin
Creators: name: McCamphill, Patrick
Publisher: name: University of Calgary
Year: 2007

description: Bibliography: p. 59-66
description: Neuromodulation is central to all nervous system function, although the precise mechanisms by which neurotransmitters affect synaptic efficacy between central neurons remains to be fully elucidated. In this study, I examined the neuromodulatory action of serotonin (5-Hydroxytryptamine or 5-HT) at central synapses between identified neurons from the pond snail Lymnaea stagnalis. Using whole-cell voltage clamp and sharp electrode recording, I show that 5-HT strongly depresses synaptic strength between cultured, cholinergic neuron visceral dorsal 4 (VD4- Presynaptic) and its serotonergic partner left pedal dorsal 1 (LPeD 1 - postsynaptic ). This inhibition was accompanied by a decrease in synaptic depression, but had no effect on postsynaptic input resistance, indicating that it is of presynaptic origin. In addition, serotonin inhibited the presynaptic calcium current (lea) on a similar time course as the change in synaptic transmission. Inclusion of the non-hydrolysable GDP analoge, GDP-??-S, in the presynaptic pipette inhibited the serotonin mediated Ca2+ current depression, as did the membrane impermeable inactive cAMP analoge 80H-cAMP. A model depicting a negative feedback mechanism is presented, where serotonin either present in the extracellular milieu, or released from the postsynaptic cell may act back on the presynaptic cell to inhibit its voltage gated calcium channels through a G-protein coupled, cAMP-mediated second messenger system.
การศึกษามโนทัศน์ที่คลาดเคลื่อนทางตรรกศาสตร์สำหรับนักศึกษาระดับปริญญาตรี สาขาวิชาคณิตศาสตร์ มหาวิทยาลัยราชภัฏมหาสารคาม ประเทศไทย
Creators: name: นวพล นนทภา
Publisher: name: Facilty of Education Rajabhat Maha Sarakham University
Year: 2563
Subjects: มโนทัศน์ที่คลาดเคลื่อน
ลักษณะมโนทัศน์ที่คลาดเคลื่อนทางตรรกศาสตร์
มโนทัศน์ที่คลาดเคลื่อนทางตรรกศาสตร์

description: Journal of Education, 17, 3, 41-53
Credit Spreads and Monetary Policy
Creators: name: Cúrdia, Vasco
name: Woodford, Michael
Publisher: name: Columbia University
Year: 2009
Subjects: Economics

description: We consider the desirability of modifying a standard Taylor rule for a central bank's interest-rate policy to incorporate either an adjustment for changes in interest-rate spreads (as proposed by Taylor, 2008, and by McCulley and Toloui, 2008) or a response to variations in the aggregate volume of credit (as proposed by Christiano et al., 2007). We consider the consequences of such adjustments for the way in which policy would respond to a variety of types of possible economic disturbances, including (but not limited to) disturbances originating in the financial sector that increase equilibrium spreads and contract the supply of credit. We conduct our analysis using the simple DSGE model with credit frictions developed in Cúrdia and Woodford (2009), and compare the equilibrium responses to a variety of disturbances under the modified Taylor rules to those under a policy that would maximize average expected utility. According to our model, a spread adjustment can improve upon the standard Taylor rule, but the optimal size is unlikely to be as large as the one proposed, and the same type of adjustment is not desirable regardless of the source of the variation in credit spreads. A response to credit is less likely to be helpful, and the desirable size (and even sign) of response to credit is less robust to alternative assumptions about the nature and persistence of the disturbances to the economy.
Competitive Equilibrium in Markets for Votes
Creators: name: Casella, Alessandra M.
name: Llorente-Saguer, Aniol
name: Palfrey, Thomas R.
Publisher: name: Columbia University
Year: 2010
Subjects: Economics

description: We develop a competitive equilibrium theory of a market for votes. Before voting on a binary issue, individuals may buy and sell their votes with each other. We define ex ante vote-trading equilibrium, identify weak sufficient conditions for existence, and construct one such equilibrium. We show that this equilibrium must always result in dictatorship and the market generates welfare losses, relative to simple majority voting, if the committee is large enough. We test the theoretical implications by implementing a competitive vote market in the laboratory using a continuous open-book multi-unit double auction.
Interaction of W(CO)$_6$ with SiO$_2$ Surfaces -- A Density Functional Study
Creators: name: Muthukumar, Kaliappan
name: Opahle, Ingo
name: Shen, Juan
name: Jeschke, Harald O.
name: Valentí, Roser
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The interaction of tungsten hexacarbonyl W(CO)$_6$ precursor molecules with SiO$_2$ substrates is investigated by means of density functional theory calculations with and without inclusion of long range van der Waals interactions. We consider two different surface models, a fully hydroxylated and a partially hydroxylated SiO$_2$ surface, corresponding to substrates under different experimental conditions. For the fully hydroxylated surface we observe only a weak interaction between the precursor molecule and the substrate with physisorption of W(CO)$_6$. Inclusion of van der Waals corrections results in a stabilization of the molecules on this surface, but does not lead to significant changes in the chemical bonding. In contrast, we find a spontaneous dissociation of the precursor molecule on the partially hydroxylated SiO$_2$ surface where chemisorption of a W(CO)$_5$ fragment is observed upon removal of one of the CO ligands from the precursor molecule. Irrespective of the hydroxylation, the precursor molecule prefers binding of more than one of its CO ligands. In the light of these results, implications for the initial growth stage of tungsten nano-deposits on SiO$_2$ in an electron beam induced deposition process are discussed.
description: 8 pages, 6 figures, submitted to Phys. Rev. B
Endowments, preferences, abatement and voting: Microfoundations of environmental Kuznets curves
Creators: name: Talikoff, Alexander Strickland Pfaff
name: Chaudhuri, Shubham
name: Nye, Howard L. M.
Publisher: name: Columbia University
Year: 2002
Subjects: subject: Economics
subject: Ecology
subject: FOS: Biological sciences

description: Will economic growth inevitably degrade the environment, throughout development? This paper presents a simple household-choice framework that emphasizes the tradeoff between pollution-causing consumption and pollution-reducing abatement expenditures. The framework yields a simple explanation for Environmental Kuznets Curves (EKCs, i.e. non-monotonic, upward-turning paths of environment while development continues) and facilitates analysis of household voting decisions that lead to public regulation of environmental externalities. Our sufficient conditions, more general than the literature, make clear that an asymmetric endowment (i.e. positive environmental quality but zero consumption at zero income) is sufficient for an EKC given standard preferences and a wide range of abatement technologies. The key is that the MRS leads the household to prefer not to abate (or to vote for whatever 'abatement' implies) at low income levels. Without the endowment, abatement technologies alone are insufficient for an EKC path. For a multi-agent setting with externalities, an analogous result is derived in which the chosen tax rate rises with income and environmental quality at first falls and later rises.
In This Corner: An Analysis of Federal Boxing Legislation
Creators: name: Ehrlichman, Brad
Publisher: name: Columbia University
Year: 2011
Subjects: subject: Boxing--Law and legislation
subject: Sports--Law and legislation
subject: Law
subject: FOS: Law

description: Muhammad Ali—arguably the greatest boxer of all time—lay beaten in a hospital bed. Defeated by his former sparring partner, Larry Holmes, Ali was battered and prone: King Arthur run through by Mordred. An aide to Don King, Ali's long-time promoter, stole into the room with a briefcase. At the time, King owed Ali over $1 million. Inside the briefcase was $50,000 in cash, which Ali— defeated—accepted after signing a release dropping all claims against King. While the Senate's version of what was to ultimately become the Muhammad Ali Boxing Reform Act ("Ali Act"), referenced only Ali's "unsurpassed" "career achievements and personal contributions to the sport [of boxing]," it is likely that this shameful episode was present in legislators' minds when honoring their bill's revered—yet tragic—eponym.
Investigation and chemical composition of plants used as anti-termite infestation and repellant in eastern Tigray, Ethiopia
Creators: name: Badasa, Shilashi
name: Mezgebe, Teklay
name: Tilahun, Yemane
Publisher: name: Journal of Science and Sustainable Development
Year: 2018

description: Development of insect resistance to synthetic chemical, the high operational cost, environmental pollution, toxicity to humans and harmful effect on non-target organisms have created the need for developing alternative approaches to control insect pest. Botanical survey and extraction of top three plants was conducted to identify the plants used against termites’ infestation and to screen chemical composition. The present research reports a total 15 plants used to control termites’ infestation as the information collected and recorded from the study area (table-2). Phytochemical analysis was conducted for top three plants depends on informants’ ideas and extracted by Maceration with acetone (Nicotiana glauca Graham, Euphorbia cactus Boiss and Aloe vera L) showed that presence of various active ingredients (table-5). The highest repellency was induced by positive control called diazinon (98.33%). Acetone extract of Nicotiana glauca Graham was found to be more repellency at 1.00gm/mL (90.48%) at all concentrations than Euphorbia cactus followed by Aloevera L however, no repellence was observed for negative untreated control. Acetone extract of Nicotiana glauca Graham test has shown best level of mortality than Euphorbia cactus Boiss and Aloe vera L extracts.
description: Journal of Science and Sustainable Development, Vol. 6 No. 2 (2018)
Improvising New Consonance: Following the Subterranean Connections between North American and Italian Avant-Garde Collectives (1963–1976)
Creators: name: Bertolani, Valentina
Publisher: name: Arts
Year: 2018
Subjects: subject: improvisation
subject: collective improvisation
subject: experimental music
subject: avant-garde
subject: 1960s
subject: 1970s
subject: Canadian music
subject: American music
subject: Italian music
subject: cultural diplomacy
subject: experimentalism
subject: Music

description: “Improvising New Consonance: The Subterranean Connections Between North American and Italian Avant-Garde, 1963–1976” is grounded in both music history and music analysis and explores the communities created around collective improvisation in the Bay Area, Rome, and Montreal through four case studies: New Music Ensemble, Gruppo di Improvvisazione Nuova Consonanza, Musica Elettronica Viva and MuD / Sonde. This research challenges the understanding of collective experimental improvisation as a genre, framing the phenomenon through the contemporary paradigm of “artistic practice as research.” This reading favours a broader understanding of experimentalism as a cross-generic phenomenon. The work is articulated in two interconnected and equally important parts to sustain my argument: 1. Using Actor-Network Theory, I examine what cultural policies were put in place within a Cold War and post-colonial context to support international exchanges among otherwise extremely localized experiences. This geography challenges dominant narratives about post-war music, normally focussed north of the Alps and on the US East Coast. 2. Building on Steinbeck’s work on the Art Ensemble of Chicago, I analyze the collective practices that allowed the groups to develop unconventional improvisatory responses. I discuss exercises developed to solve peculiar improvisational problems, and assessment strategies used to evaluate recorded sessions, linking this body of knowledge to the recordings we have to build an innovative analytical framework.
การประเมินความต้องการจำเป็นในการจัดการด้านการออกกำลังกายและกีฬาของมหาวิทยาลัยราชภัฏตามแนวคิดของเครือข่ายมหาวิทยาลัยอาเซียน ด้านการส่งเสริมสุขภาพ
Creators: name: พลากร มะโนรัตน์
Publisher: name: Facilty of Education Rajabhat Maha Sarakham University
Year: 2563
Subjects: ความต้องการจำเป็น
การออกกำลังกายและกีฬา
กรอบแนวคิดเครือข่ายมหาวิทยาลัยส่งเสริมสุขภาพ

description: Journal of Education, 17, 3, 55-66
Molecular epidemiology of gastric and esophageal cancer survival
Creators: name: Bashash, Morteza
Publisher: name: University of British Columbia
Year: 2011

description: Introduction: Gastric and esophageal cancers are among the deadliest forms of cancer. Studies of human cancer susceptibility examine factors associated with the incidence of disease. Studies of human cancer prognosis and prediction examine factors associated with disease outcomes. This dissertation is about molecular and other factors that affect survival of gastric and esophageal cancer patients. Methods: Population-based registry data linked with patient outcome data was used to describe the epidemiology of gastric and esophageal cancers in BC; to compare survival of cancer patients in BC, and Ardabil, Iran and to describe differences in survival of BC patients of different ethnicity. The ethnicity of patients was determined based on lists of names corresponding to each ethnic group. A prospective cohort study was conducted to examine the effect of genetic polymorphisms in TIMP (1-4) and MMP (2, 7 and 9) genes. Results: Analysis of cancer registry data points to several factors associated with gastric and esophageal cancer survival. Patients with gastric cardia experience worse survival compared to other gastric cancers. Ethnicity of gastric and esophageal cancer patients is associated with their survival. Gastric and esophageal cancer patients diagnosed in British Columbia have better survival compared to those daignosed in Adabil, Iran. Genetic polymorphisms are also associated with survival. My prospective study identified 4 genetic polymorphisms at TIMP-3 associated with survival of esophageal adenocarcinoma and gastroesophageal junction (GEJ). Conclusion: Besides established prognostic indicators, other factors affect survival of gastric and esophageal cancers. Differences in survival by ethnicity support the importance of ethnicity as a prognostic factor. Survival differences between BC and Ardabil are likely due to disease characteristics and patient factors, in addition to differences in healthcare systems. TIMP3 genetic polymorphisms are promising prognostic factors for adenocarcinoma of esophagus and GEJ. Modeling prognosis based on host factors, including ethnicity and genetic polymorphisms, is an emerging field of translational cancer research. More research is needed to fully explore the functional effects of TIMP3 polymorphisms, and to identify both genetic and lifestyle factors underlying the effect ethnicity on survival.
Protecting Minorities in Binary Elections
Creators: name: Casella, Alessandra M.
name: Ehrenberg, Shuky
name: Gelman, Andrew E.
Publisher: name: Columbia University
Year: 2008
Subjects: Economics

description: Democratic systems are built, with good reason, on majoritarian principles, but their legitimacy requires the protection of strongly held minority preferences. The challenge is to do so while treating every voter equally and preserving aggregate welfare. One possible solution is storable votes: granting each voter a budget of votes to cast as desired over multiple decisions. During the 2006 student elections at Columbia University, we tested a simple version of this idea: voters were asked to rank the importance of the different contests and to choose where to cast a single extra "bonus vote," had one been available. We used these responses to construct distributions of intensities and electoral outcomes, both without and with the bonus vote. Bootstrapping techniques provided estimates of the probable impact of the bonus vote. The bonus vote performs well: when minority preferences are particularly intense, the minority wins at least one of the contests with 15.30 percent probability; and, when the minority wins, aggregate welfare increases with 85.95 percent probability. When majority and minority preferences are equally intense, the effect of the bonus vote is smaller and more variable but on balance still positive.
Relaxation to quantum equilibrium for Dirac fermions in the de Broglie-Bohm pilot-wave theory
Creators: name: Colin, Samuel
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Numerical simulations indicate that the Born rule does not need to be postulated in the de Broglie-Bohm pilot-wave theory, but arises dynamically (relaxation to quantum equilibrium). These simulations were done for a particle in a two-dimensional box whose wave-function obeys the non-relativistic Schroedinger equation and is therefore scalar. The chaotic nature of the de Broglie-Bohm trajectories, thanks to the nodes of the wave-function which act as vortices, is crucial for a fast relaxation to quantum equilibrium. For spinors, we typically do not expect any node. However, in the case of the Dirac equation, the de Broglie-Bohm velocity field has vorticity even in the absence of nodes. This observation raises the question of the origin of relaxation to quantum equilibrium for fermions. In this article, we provide numerical evidence to show that Dirac particles also undergo relaxation, by simulating the evolution of various non-equilibrium distributions for two-dimensional systems (the 2D Dirac oscillator and the Dirac particle in a spherical 2D box).
description: 11 pages, 9 figures
Aviram-Ratner rectifying mechanism for DNA base pair sequencing through graphene nanogaps
Creators: name: Agapito, Luis A.
name: Gayles, Jacob
name: Wolowiec, Christian
name: Kioussis, Nicholas
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We demonstrate that biological molecules such as Watson-Crick DNA base pairs can behave as biological Aviram-Ratner electrical rectifiers because of the spatial separation and weak hydrogen bonding between the nucleobases. We have performed a parallel computational implementation of the ab-initio non-equilibrium Green's function (NEGF) theory to determine the electrical response of graphene---base-pair---graphene junctions. The results show an asymmetric (rectifying) current-voltage response for the Cytosine-Guanine base pair adsorbed on a graphene nanogap. In sharp contrast we find a symmetric response for the Thymine-Adenine case. We propose applying the asymmetry of the current-voltage response as a sensing criterion to the technological challenge of rapid DNA sequencing via graphene nanogaps.
Social security, retirement, and the single-mindedness of the electorate
Creators: name: Sala-I-Martin, Xavier
name: Mulligan, Casey B.
Publisher: name: Columbia University
Year: 2003
Subjects: subject: Economics
subject: Political science
subject: FOS: Political science

description: We propose a positive theory that is consistent with two important features of social security programs around the world: (1) they redistribute income from young to old and (2) they induce retirement. We construct a voting model that includes a "political campaign" or "debate" prior to the election. The model incorporates "single-mindedness" of the groups that do not work: while the workers divide their political capital between their "age concerns" and "occupational concerns", the retired concentrate all their political capital to support their age group. In our model, the elderly end up getting transfers from the government (paid by the young) and distortionary labor income taxes induce the retirement of the elderly. In addition, our model predicts that occupational groups that work more will tend to have more political power. The opposite is true for non-occupational groups (such as the elderly). We provide some evidence that supports these additional predictions.
More on the relation between the two physically inequivalent decompositions of the nucleon spin and momentum
Creators: name: Wakamatsu, Masashi
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In a series of papers, we have established the existence of two gauge-invariant decompositions of the nucleon spin, which are physically nonequivalent. The orbital angular momenta of quarks and gluons appearing in these two decompositions are gauge-invariant dynamical orbital angular momenta and "generalized" canonical orbital angular momenta with gauge-invariance, respectively. The key quantity, which characterizes the difference between these two types of orbital angular momenta is what-we-call the {\it potential angular momentum}. We argue that the physical meaning of the potential angular momentum in the nucleon can be made more transparent, by investigating a related but much simpler example from electrodynamics. We also make clear several remaining issues in the spin and momentum decomposition problem of the nucleon. We clarify the relationship between the evolution equations of orbital angular momenta corresponding to the two different decompositions above. We also try to answer the question whether the two different decompositions of the nucleon momentum really lead to different evolution equations, thereby predicting conflicting asymptotic values for the quark and gluon momentum fractions in the nucleon.
description: The version to appear in Physical Review D, LaTeX, 47 pages, 4 figures
การสำรวจกรอบมาตรฐานคุณวุฒิระดับปริญญาตรี สาขาวิชาครุศาสตร์และสาขาวิชาศึกษาศาสตร์
Creators: name: จิรวัฒน์ กิติพิเชฐสรรค์
Publisher: name: Facilty of Education Rajabhat Maha Sarakham University
Year: 2563
Subjects: กรอบมาตรฐานคุณวุฒิ
ระดับปริญญาตรี
การศึกษา

description: Journal of Education, 17, 3, 67-76
title: Journal Bildende Kunst.Gestaltung.Musik.Bühne.Wissen
Creators: name: Universität Der Künste Berlin
Publisher: name: Verlag der Universität der Künste
Year: 2023
Subjects: subject: 7 Künste und Unterhaltung
subject: 700 Künste; Bildende und angewandte Kunst

description: Ausgabe 21 (2023, Sommer)
description: Journal Bildende Kunst.Gestaltung.Musik.Bühne.Wissen; 2023, Sommer
A Psychological Perspective on Image Interpretation in Acute Ischemic Stroke: Factors Affecting Non-Contrast CT ASPECTS Reliability
Creators: name: Wilson, Alexis Terrin Connett
Publisher: name: Cumming School of Medicine
Year: 2018
Subjects: subject: ischemic stroke
subject: medical decision making
subject: medical image interpretation
subject: computed tomography
subject: Education--Health
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biophysics--Medical
subject: Medicine and Surgery
subject: Radiology

description: The Alberta Stroke Program Early CT Score (ASPECTS) is a semiquantitative scale to assess the extent of early ischemic changes on non-contrast CT in acute ischemic stroke patients. This is crucial for prognostication and treatment selection. Recent studies have revealed significant heterogeneity in reported measures of inter-rater reliability in ASPECTS, and this thesis aims to investigate the reasons underlying this phenomenon from the perspective of clinicians’ cognitive processes. First, this work explores relevant topics in the psychology of image interpretation and, on this psychological basis, proposes potential causes of inconsistent ASPECTS reliability. Possible strategies to improve clinicians’ inter- and intra-rater reliability are also discussed. The effect of image reading context variables and rater expertise on ASPECTS inter-rater reliability was then investigated. Raters of different experience levels scored ASPECTS on baseline non-contrast CT scans under three prior-information conditions (NCCT only, NCCT with access to clinical information, NCCT with access to clinical information and multiphase CT angiography) and three reading-context conditions (high/low ambient light, time pressure). The results indicate that these variables have the capacity to affect ASPECTS reliability. This work highlights the importance of acknowledging that medical image interpretation can be influenced by seemingly irrelevant external and internal factors like reading environment characteristics or physician-level variables. Giving more consideration to these variables in clinical and educational settings could improve the utility of tools like ASPECTS.
Variation of complex structures and the stability of Kähler-Ricci Solitons
Creators: name: Hall, Stuart James
name: Murphy, Thomas
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We investigate the linear stability of Kähler-Ricci solitons for perturbations induced by varying the complex structure within a fixed Kähler class. We calculate stability for the known examples of Kähler-Ricci solitons.
description: 13 pages v2 added reference to work of Y. Wang
Factors Influencing Indigenous Knowledge of Rangeland Management Practices in Borana Pastoral Areas, Southern Ethiopia
Creators: name: Tafesse, Benti
Publisher: name: Journal of Science and Sustainable Development
Year: 2018

description: In most pastoral areas of Ethiopia, rangelands have traditionally been managed by customary institutions, especially in Borana but with the start of various pressures, this management system is increasingly undermined and the interventions ended up with little success story but more of in favor of environmental degradations. Looking into indigenous rangeland management practices of pastoral community is a useful way to develop sustainable rangeland productivity. Rangeland plays an essential role in the livelihood activities of Ethiopian pastoralists as well as Ethiopian economy. Numerous researches have been done on rangeland management practices, but little study has been done with respect to the determinants of indigenous rangeland management in specific social, economic and ecological context. In this case, the aim of the study was to assess the determinants of the indigenous rangeland management practices of pastoral communities and assess perception of pastoral households towards the attributing causes of rangeland degradation in Borana. The study employed descriptive and inferential statistical methods to analyze the data. The findings indicated that the indigenous practice accurately reflects the productivity of the rangeland since the Borana area is unpredictable environment and victim for severe drought every year. The results of binary logit regression showed that a unit increase in age of the household head, the odds ratio in favor of practicing in traditional rangelands management increase by 1.096. Holding other variables constant, a unit increase in cultivated farm size would decrease the odds ratio in favor of practicing traditional management by a factor of 0.618. In Borana area, grazing land and water resources are jointly handled. Hence, privately owned grazing land and water points disturb patterns of mobility in a way grazing land use becomes inefficient as grazing concentrates close to the water points, leading to degradation of the rangelands. Access to communal water point was also found to be significant influence on respondents’ traditional rangeland management practice at 10% significance level (p < 0.1). On the other hand, the result of odd-ratio indicates that, access to communal water point will increase the probability of rangeland management practice by 0.22 percent. The study recommends bases for ecologically sound and culturally appropriate indigenous rangeland management practices.
description: Journal of Science and Sustainable Development, Vol. 6 No. 2 (2018)
A microchip optomechanical accelerometer
Creators: name: Krause, Alexander G.
name: Winger, Martin
name: Blasius, Tim D.
name: Lin, Qiang
name: Painter, Oskar
Publisher: name: arXiv
Year: 2012
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The monitoring of accelerations is essential for a variety of applications ranging from inertial navigation to consumer electronics. The basic operation principle of an accelerometer is to measure the displacement of a flexibly mounted test mass; sensitive displacement measurement can be realized using capacitive, piezo-electric, tunnel-current, or optical methods. While optical readout provides superior displacement resolution and resilience to electromagnetic interference, current optical accelerometers either do not allow for chip-scale integration or require bulky test masses. Here we demonstrate an optomechanical accelerometer that employs ultra-sensitive all-optical displacement read-out using a planar photonic crystal cavity monolithically integrated with a nano-tethered test mass of high mechanical Q-factor. This device architecture allows for full on-chip integration and achieves a broadband acceleration resolution of 10 μg/rt-Hz, a bandwidth greater than 20 kHz, and a dynamic range of 50 dB with sub-milliwatt optical power requirements. Moreover, the nano-gram test masses used here allow for optomechanical back-action in the form of cooling or the optical spring effect, setting the stage for a new class of motional sensors.
description: 16 pages, 9 figures
Economic growth and investment in the Arab world
Creators: name: Sala-I-Martin, Xavier
name: Artadi, Elsa V.
Publisher: name: Columbia University
Year: 2002
Subjects: Economics

description: This paper analyses the economic growth performance in the Arab world over the last forty years. The Arab world has managed to reduce poverty performance despite its relatively disappointing growth performance. We relate this poor performance of both oil and non-oil producers to investment. Contrary to widespread belief, we do not find evidence that low quantity of investment is the main of low growth. The decline in the investment rate followed rather than preceded the reduction in the aggregate growth rate. We conclude that the low quality of investment projects is the key determinant of growth. The excessive reliance on public investment, the low quality of financial institutions, the bad business environment (due to political and social instability and to excessive public intervention and overregulation) and the low quality of human capital are important determinants of systematically unproductive investment decisions and, thus, low economic growth.
Overlooked and undervalued Sector: Exploring the Experience of Female Domestic Workers in Burayu and Sebeta Towns, Oromia, Ethiopia
Creators: name: Dugassa, Dereje
name: Tesfaye, Shibiru
Publisher: name: Journal of Science and Sustainable Development
Year: 2018

description: Domestic workers provide crucial household and care services to many families and contribute to the economic development of the country. They relieve their employers of countless responsibilities and help families to manage their day-to-day stresses and demands on their time. The aim of this research was to explore the lived experiences of domestic workers in Burayu and Sebeta towns. The study employed a qualitative research approach using a descriptive research design. Eight domestic workers were selected by using snowball sampling. Domestic workers reported that lack of family support and early marriage are the major factors that force them to engage in live-in domestic work. The nature of the agreement made between domestic workers and employers was through informal and formal agreements. Supporting their family member and saving money from what they earn to meet their needs considered as the benefits of working in private home as domestic worker. Despite its benefits, working in their employer’s home has a major impact on workers’ personal autonomy, mobility and decisions about their future. They also subjected to excessive work load without any additional payment which may worsen their life. To overcome the overwhelming and demanding nature of work domestic workers used seeking social support and crying as coping strategies. It was recommended that domestic workers need legal protection just as any other employees. They must enjoy their fundamental rights to form and join a trade union for collective bargain with their employers.
description: Journal of Science and Sustainable Development, Vol. 6 No. 2 (2018)
Avifauna of Entoto Mountain Forest, Ethiopia: Diversity and Potential for Tourism Development
Creators: name: Asefa, Addisu
Publisher: name: Journal of Science and Sustainable Development
Year: 2018

description: Information on ornithological significances of important bird areas is required to develop appropriate actions for conservation of the birds and their habitats and to untap their potential contribution to local and national economy through avitourism activities. This study was conducted between December 2016 and January 2017 to determine bird diversity in the Entoto Mountain and to examine the potential of the area for developing avitourism. Birds were surveyed at systematicaly designated counting points. Overall, 517 individual birds belonging to 49 species were recorded in the entire study area. Of the total species recorded: i) two species were endemic [Abyssinian Catbird (Parophasma galiniei) and Yellow-fronted Parrot (Poicephalus flavifrons)]; ii) 11 species were nearly endemic (shared with one or two other countries); iii) three were globally threatened; and, iv) 21 species (43% of such species known from Ethiopia) were Afro-tropical highland biome-restricted assemblage. These findings, coupled to its close proximity to Addis, the presence of several cultual/historical sites in the area and easy accessibility, suggest that Entoto mountain area can be considered as with high potential for developing avitourism as one segment of ecotourism in the area.
description: Journal of Science and Sustainable Development, Vol. 6 No. 2 (2018)
The role of FOXM1 and co-factors in breast cancer – endoplasmic reticulum stress, epigenetics, endocrine therapy and chemotherapy
Creators: name: Yong, Jay Sze
Publisher: name: Imperial College London
Year: 2021

description: Breast cancer is an umbrella term for heterogeneous diseases that originated from breast tissues. To date, five main treatment strategies are available for breast cancer treatment – comprising of surgery, radiotherapy, chemotherapy, hormone therapy, and biological therapy – and these treatments are not categorically exclusive but are used in combinations. The treatment arrangement is also dependent on the type, size, location, and stage of cancer. Nevertheless, the interpretation and complete removal of the disease based on sequencing results remain a challenge. In order to better tackle the disease, different classifiers have been established to categorise breast cancer cases into buckets with their own distinct features. Particularly, molecular subtyping separates breast cancer cases based on the presence of specific markers such as ESR1, PR, HER2, and Ki-67 with diverse prognostic outcomes and treatment responses in patients. FOX proteins belong to a transcription factor superfamily that drives not only important molecular mechanisms in normal cells, but the aberrant regulation of these members leads to oncogenic outcomes and cancer progression. Particularly, FOXM1 is an oncogene that is associated with the hallmarks of cancer. It has been shown that FOXM1 cistrome predicts breast cancer metastatic outcomes better than FOXM1 expression levels. Therefore, clarity about FOXM1 cistrome and interactome needs to be prioritised to improve breast cancer treatment and reduce treatment resistance. In this dissertation, I built on existing knowledge of the role of FOXM1 in breast cancer cell lines by providing new preliminary insights that pave new roads for future studies in hormonal and chemotherapeutic response, unfolded protein response, and epigenetic mechanism. FOXM1 inhibitors are attractive agents to constitute combinatorial treatment with fulvestrant for constitutively activate ESR1- positive breast cancer with lower toxicity to cells. Additionally, FOXM1 serves a role in unfolded protein response in breast cancer cells by a potential axis with endoplasmic reticulum stress effector, DDIT3. Lastly, FOXM1 differentially interacts with DNA methyltransferases – specific interaction of FOXM1 and DNMT3B was detected in MCF-7 and MCF7-EpiR cell lines. Collectively, this study extended our understandings of the molecular diversity of FOXM1 and its cofactors in breast cancer cell lines and may serve as a stepping stone to identify prognostic markers and treatment targets in breast cancer.
Vibrational spectrum of solid picene (C_22H_14)
Creators: name: Joseph, B.
name: Boeri, L.
name: Malavasi, L.
name: Capitani, F.
name: Artioli, G. A.
name: Protti, S.
name: Fagnoni, M.
name: Albini, A.
name: Marini, C.
name: Baldassarre, L.
name: Perucchi, A.
name: Lupi, S.
name: Postorino, P.
name: Dore, P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Recently, Mitsuhashi et al., have observed superconductivity with transition temperature up to 18 K in potassium doped picene (C22H14), a polycyclic aromatic hydrocarbon compound [Nature 464 (2010) 76]. Theoretical analysis indicate the importance of electron-phonon coupling in the superconducting mechanisms of these systems, with different emphasis on inter- and intra-molecular vibrations, depending on the approximations used. Here we present a combined experimental and ab-initio study of the Raman and infrared spectrum of undoped solid picene, which allows us to unanbiguously assign the vibrational modes. This combined study enables the identification of the modes which couple strongly to electrons and hence can play an important role in the superconducting properties of the doped samples.
The two-stage dynamics in the Fermi-Pasta-Ulam problem: from regular to diffusive behavior
Creators: name: Ponno, Antonio
name: Christodoulidi, Helen
name: Skokos, Charalampos
name: Flach, Sergej
Publisher: name: arXiv
Year: 2011
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: A numerical and analytical study of the relaxation to equilibrium of both the Fermi-Pasta-Ulam (FPU) alpha-model and the integrable Toda model, when the fundamental mode is initially excited, is reported. We show that the dynamics of both systems is almost identical on the short term, when the energies of the initially unexcited modes grow in geometric progression with time, through a secular avalanche process. At the end of this first stage of the dynamics the time-averaged modal energy spectrum of the Toda system stabilizes to its final profile, well described, at low energy, by the spectrum of a q-breather. The Toda equilibrium state is clearly shown to describe well the long-living quasi-state of the FPU system. On the long term, the modal energy spectrum of the FPU system slowly detaches from the Toda one by a diffusive-like rising of the tail modes, and eventually reaches the equilibrium flat shape. We find a simple law describing the growth of tail modes, which enables us to estimate the time-scale to equipartition of the FPU system, even when, at small energies, it becomes unobservable.
description: 31 pages, 11 figures, submitten in Chaos
Detecting Majorana fermions by nonlocal entanglement between quantum dots
Creators: name: Wang, Zhi
name: Hu, Xiao
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Nonlocal entanglement between two quantum dots can be generated through Majorana fermions. The two Majorana fermions at the ends of an one-dimensional topological superconductor form a nonlocal fermion level, coupling to the occupation states of two quantum dots put close to the two ends, and the entire system will come into an entangled state. After introducing a charging energy by a capacitor, entanglement of the entire system can manifest itself through the nonlocal entanglement between the two quantum dots. That is, when measuring the electron occupations of the quantum dots, the measurement result of one quantum dot will influence the measurement result of the other quantum dot. This nonlocal entanglement between the two quantum dots is a strong evidence of the nonlocal nature of the fermion level constructed by two Majorana fermions.
description: 4 pages, 4 figures
Dynamics of competing ideas in complex social systems
Creators: name: Wang, Yubo
name: Xiao, Gaoxi
name: Liu, Jian
Publisher: name: arXiv
Year: 2011
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Individuals accepting an idea may intentionally or unintentionally impose influences in a certain neighborhood area, making other individuals within the area less likely or even impossible to accept other competing ideas. Depending on whether such influences strictly prohibit neighborhood individuals from accepting other ideas or not, we classify them into exclusive and non-exclusive influences, respectively. Our study reveals for the first time the rich and complex dynamics of two competing ideas with neighborhood influences in scale-free social networks: depending on whether they have exclusive or non-exclusive influences, the final state varies from multiple coexistence to founder control to exclusion, with different sizes of population accepting each of the ideas respectively. Such results provide insights helpful for better understanding the spread (and the control of spread) of ideas in human society.
description: 23 pages, 13 figures, accepted for publication in New Journal of Physics