cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Introduction to Mindfulness Practice for College and University Students: an Instructor’s Manual and Syllabus
Publisher: name: University of Virginia
Year: 2017
Subjects: MBSR
undergraduate
meditation
Mindfulness-Based Stress Reduction
mindful

description: There are doubtless many effective ways to teach an introductory mindfulness practice class in a college or university setting. This is one of them. Mindfulness practice can only be taught from one’s own experience. My experience, as a student and a teacher, has come mainly through the MBSR Program developed by Jon Kabat-Zinn and described in detail in Full Catastrophe Living. It is not my purpose to restate or summarize that work. Rather, I would recommend it (enthusiastically) to anyone not already familiar with it. My purpose is to describe an undergraduate syllabus that is derived from the MBSR program. It is taught in a similar manner and covers much of the same content. The syllabus described below may be of use to teachers who are unfamiliar with MBSR, but it is primarily intended to be a resource for other MBSR teachers who have the interest and opportunity to try reaching a younger population.
Assessment of magnetic flux density properties of electromagnetic noninvasive phrenic nerve stimulations for environmental safety in an ICU environment
Creators: name: Kuhn, K. Friedrich
name: Grunow, Julius J.
name: Leimer, Pascal
name: Lorenz, Marco
name: Berger, David
name: Schefold, Joerg C.
name: Weber-Carstens, Steffen
name: Schaller, Stefan J.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: intensive care unit (ICU)
subject: electromagnetic stimulation
subject: induce contractions
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Diaphragm weakness affects up to 60% of ventilated patients leading to muscle atrophy, reduction of muscle fiber force via muscle fiber injuries and prolonged weaning from mechanical ventilation. Electromagnetic stimulation of the phrenic nerve can induce contractions of the diaphragm and potentially prevent and treat loss of muscular function. Recommended safety distance of electromagnetic coils is 1 m. The aim of this study was to investigate the magnetic flux density in a typical intensive care unit (ICU) setting. Simulation of magnetic flux density generated by a butterfly coil was performed in a Berlin ICU training center with testing of potential disturbance and heating of medical equipment. Approximate safety distances to surrounding medical ICU equipment were additionally measured in an ICU training center in Bern. Magnetic flux density declined exponentially with advancing distance from the stimulation coil. Above a coil distance of 300 mm with stimulation of 100% power the signal could not be distinguished from the surrounding magnetic background noise. Electromagnetic stimulation of the phrenic nerve for diaphragm contraction in an intensive care unit setting seems to be safe and feasible from a technical point of view with a distance above 300 mm to ICU equipment from the stimulation coil.
Evidence for a thromboembolic pathogenesis of lung cavitations in severely ill COVID-19 patients
Creators: name: Kruse, Jan Matthias
name: Zickler, Daniel
name: Lüdemann, Willie M.
name: Piper, Sophie K.
name: Gotthardt, Inka
name: Ihlow, Jana
name: Greuel, Selina
name: Horst, David
name: Kahl, Andreas
name: Eckardt, Kai-Uwe
name: Elezkurtaj, Sefer
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: COVID-19 patients
subject: acute respiratory syndrome
subject: acute respiratory distress syndrome (ARDS)
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) induces lung injury of varying severity, potentially causing severe acute respiratory distress syndrome (ARDS). Pulmonary injury patterns in COVID-19 patients differ from those in patients with other causes of ARDS. We aimed to explore the frequency and pathogenesis of cavitary lung lesions in critically ill patients with COVID-19. Retrospective study in 39 critically ill adult patients hospitalized with severe acute respiratory syndrome coronavirus 2 including lung injury of varying severity in a tertiary care referral center during March and May 2020, Berlin/Germany. We observed lung cavitations in an unusually large proportion of 22/39 (56%) COVID-19 patients treated on intensive care units (ICU), including 3/5 patients without mechanical ventilation. Median interquartile range (IQR) time between onset of symptoms and ICU admission was 11.5 (6.25-17.75) days. In 15 patients, lung cavitations were already present on the first CT scan, performed after ICU admission; in seven patients they developed during a subsequent median (IQR) observation period of 48 (35-58) days. In seven patients we found at least one cavitation with a diameter>2 cm (maximum 10 cm). Patients who developed cavitations were older and had a higher body mass index. Autopsy findings in three patients revealed that the cavitations reflected lung infarcts undergoing liquefaction, secondary to thrombotic pulmonary artery branch occlusions. Lung cavitations appear to be a frequent complication of severely ill COVID-19 patients, probably related to the prothrombotic state associated with COVID-19.
Automated Generation of Keywords from the NLP Perspective
Creators: name: Mikołajczyk-Bareła, Agnieszka
Publisher: name: Zenodo
Year: 2022
Subjects: bibliographical data

description: The presentation was held during the Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data (October 12-14, 2022) organised by the Bibliographical Data Working Group of the DARIAH-ERIC.
description: The Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data has been supported by the DARIAH ERIC.
Low-dose rapamycin does not impair vascular integrity and tubular regeneration after kidney transplantation in rats
Creators: name: Hoff, Uwe
name: Markmann, Denise
name: Nieminen-Kelhä, Melina
name: Budde, Klemens
name: Hegner, Björn
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: mTOR inhibitors
subject: kidney transplantation
subject: rats
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: mTOR inhibitors offer advantages after kidney transplantation including antiviral and antitumor activity besides facilitating low calcineurin inhibitor exposure to reduce nephrotoxicity. Concerns about adverse effects due to antiproliferative and antiangiogenic properties have limited their clinical use particularly early after transplantation. Interference with vascular endothelial growth factor (VEGF)-A, important for physiologic functioning of renal endothelial cells and tubular epithelium, has been implicated in detrimental renal effects of mTOR inhibitors. Low doses of Rapamycin (loading dose 3 mg/kg bodyweight, daily doses 1.5 mg/kg bodyweight) were administered in an allogenic rat kidney transplantation model resulting in a mean through concentration of 4.30 ng/mL. Glomerular and peritubular capillaries, tubular cell proliferation, or functional recovery from preservation/reperfusion injury were not compromised in comparison to vehicle treated animals. VEGF-A, VEGF receptor 2, and the co-receptor Neuropilin-1 were upregulated by Rapamycin within 7 days. Rat proximal tubular cells (RPTC) responded in vitro to hypoxia with increased VEGF-A and VEGF-R1 expression that was not suppressed by Rapamycin at therapeutic concentrations. Rapamycin did not impair proliferation of RPTC under hypoxic conditions. Low-dose Rapamycin early posttransplant does not negatively influence the VEGF network crucial for recovery from preservation/reperfusion injury. Enhancement of VEGF signaling peritransplant holds potential to further improve outcomes.
Colección De 6 Poemas Para La Profunda Reflexión Del Alma
Creators: name: Masís, Héctor
Publisher: name: Zenodo
Year: 2025

description: OBRAS CREATIVAS EN PROSA Y RIMA DESDE UN ENFOQUE MUY PROPIO Y EXPERIENCIA BIEN PERSONAL DE SU AUTOR: HÉCTOR MASÍS.

Selección De 6 Poemas Con Verdadera Inspiración Del Corazón - Colección De 6 Poemas Para La Profunda Reflexión Del Alma - Reunión De 6 Tratados Para Una Íntima Meditación Espiritual Y La Auto Edificadora Renovación Mental - Exposición De 6 Pensamientos Introspectivos Acerca De Asuntos Específicos De La Vida Humana En General.
Impact of geometry on light collection efficiency of scintillation detectors for cryogenic rare event searches
Creators: name: Danevich, F. A.
name: Kobychev, V. V.
name: Kobychev, R. V.
name: Kraus, H.
name: Mikhailik, V. B.
name: Mokina, V. M.
name: Solsky, I. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Simulations of photon propagation in scintillation detectors were performed with the aim to find the optimal scintillator geometry, surface treatment, and shape of external reflector in order to achieve maximum light collection efficiency for detector configurations that avoid direct optical coupling, a situation that is commonly found in cryogenic scintillating bolometers in experimental searches for double beta decay and dark matter. To evaluate the light collection efficiency of various geometrical configurations we used the ZEMAX ray-tracing software. It was found that scintillators in the shape of a triangular prism with an external mirror shaped as truncated cone gives the highest light collection efficiency. The results of the simulations were confirmed by carrying out measurements of the light collection efficiencies of CaWO4 crystal scintillators. A comparison of simulated and measured values of light output shows good agreement
Automated Generation of Subject Headings using Annif and Finto AI
Creators: name: Suominen, Osma
Publisher: name: Zenodo
Year: 2022
Subjects: bibliographical data

description: The presentation was held during the Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data (October 12-14, 2022) organised by the Bibliographical Data Working Group of the DARIAH-ERIC.
description: The Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data has been supported by the DARIAH ERIC.
Datos florísticos del matorral costero y vegetación relacionada de la Bahía de Todos Santos, Ensenada, B. C. /
Creators: name: Gutierrez Bernardino, Margarita
Publisher: name: Universidad Autónoma de Baja California.
Year: 2022
Subjects: subject: QK938.C6 G88 1985

description: Este trabajo se realizó a lo largo de la Bahía de Todos Santos, B.C., donde predomina un clima mediterráneo con lluvias en invierno.
Review of State Transportation Funding Initiatives
Creators: name: Gibson, Bryan
name: Van Dyke, Christopher W.
name: Waddle, Steven
name: Kreis, Steven Douglas
Publisher: name: Kentucky Transportation Center, University of Kentucky
Year: 2018

description: Abstract: Despite significant cutbacks to the funding allocated to state departments of transportation (DOTs), demand for accessible and reliable transportation has increased even as existing transportation infrastructure has continued to age. Falling gasoline tax revenues resulting from increasing fuel efficiency and technological advancements have prevented state DOTs, including the Kentucky Transportation Cabinet (KYTC), from funding and financing much-needed transportation projects. Meanwhile, the Federal Highway Trust Fund, which provides funding to states and is tied to the federal gas tax, routinely receives cash infusions from the Federal General Fund to remain solvent—the federal gas tax has not been increased since 1993. Needing to invest in urgent transportation projects while facing stagnant revenue streams has led many state DOTs and researchers to begin exploring alternative funding sources as well as strategies to modify current revenue sources (e.g., gasoline tax, registration and licensing fees) to improve their sustainability. Ensuring the public understands that adequate funding is required to meet our infrastructure needs is critical as well—especially when transitioning to alternative funding mechanisms. Copyright: © 2018 University of Kentucky, Kentucky Transportation Center
Sufia 7 Early Adoption: UVA's "Libra 2"
Year: 2016
Subjects: fedora
repository
ETD
sufia
hydra

description: Conference poster for Hydra Connect meeting, October 4, 2016 in Boston, MA. https://wiki.duraspace.org/display/hydra/Hydra+Connect+2016
External application of liver compresses to reduce fatigue in patients with metastatic cancer undergoing radiation therapy, a randomized clinical trial
Creators: name: Ghadjar, Pirus
name: Stritter, Wiebke
name: Mackensen, Irina Von
name: Mehrhof, Felix
name: Foucré, Clara
name: Ehrhardt, Vincent H.
name: Beck, Marcus
name: Gebert, Pimrapat
name: Kalinauskaite, Goda
name: Luchte, Jacqueline S.
name: Stromberger, Carmen
name: Budach, Volker
name: Eggert, Angelika
name: Seifert, Georg
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: External application
subject: Compress
subject: Cancer
subject: Metastasis
subject: Radiation therapy
subject: Fatigue
subject: Integrative medicine
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Liver compresses are frequently used in integrative medicine as supportive therapy during cancer treatment in order to reduce fatigue. We performed a pilot study to test whether the external application of yarrow liver compresses impacts fatigue in patients with metastatic cancer undergoing radiation therapy. Methods: A randomized prospective pilot trial was performed including patients with brain metastasis or bone metastasis of solid tumors. Patients underwent either palliative radiation therapy (RT) of the metastatic lesions (control group) over two weeks or the same RT with additional external application of yarrow liver compresses once daily during RT. The primary objective was improvement on the general fatigue subscale of the multidimensional fatigue inventory (MFI-20) at the end of treatment, where a mean difference of two points is considered clinically relevant. Secondary objectives included psychological distress, quality of life and qualitative analysis with self-established visual analogue scales (VAS). Mean differences in general fatigue at the end of treatment compared to baseline were analyzed using the ANCOVA test. Results: From 09/2017 to 08/2019 a total of 39 patients were randomized. Due to drop outs 24 patients (12 per group) were available for analysis. Patients in the intervention group received a mean number of 10.5 (range, 7-14) applications of yarrow liver compresses. The mean improvement at the end of therapy on the general fatigue subscale of the MFI-20 was 2 points in favor of the intervention group (p = 0.13), and all other MFI-20 subscales showed at least a trend towards improvement in favor of the intervention group. Likewise, psychological distress and VAS data was improved, the latter reaching statistical significance for the symptoms fatigue, tension and lack of drive. Major toxicities were not observed. Conclusions: External application of liver compresses appears to reduce fatigue within a clinical relevant range in patients with metastatic cancer undergoing radiation therapy. Trial registration: ISRCTN, ICTRP DRKS00012999
Importance of frequency-dependent grain boundary scattering in nanocrystalline silicon and silicon-germanium thermoelectrics
Creators: name: Hua, Chengyun
name: Minnich, Austin J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Nanocrystalline silicon and silicon-germanium alloys are promising thermoelectric materials that have achieved substantially improved figure of merits compared to their bulk counterparts. This enhancement is typically attributed to a reduction in lattice thermal conductivity by phonon scattering at grain boundaries. However, further improvements are difficult to achieve because grain boundary scattering is poorly understood, with recent experimental observations suggesting that the phonon transmissivity may depend on phonon frequency rather than being constant as in the commonly used gray model. Here, we examine the impact of frequency-dependent grain boundary scattering in nanocrystalline silicon and silicon-germanium alloys in a realistic 3D geometry using frequency-dependent variance-reduced Monte Carlo simulations. We find that the grain boundary may not be as effective as predicted by the gray model in scattering certain phonons, with a substantial amount of heat being carried by low frequency phonons with mean free paths longer than the grain size. Our result will help guide the design of more efficient thermoelectrics.
A cognitive fingerprint in human random number generation
Creators: name: Schulz, Marc-André
name: Baier, Sebastian
name: Timmermann, Benjamin
name: Bzdok, Danilo
name: Witt, Karsten
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: random number generation
subject: cognitive fingerprint
subject: individual preference
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Is the cognitive process of random number generation implemented via person-specific strategies corresponding to highly individual random generation behaviour? We examined random number sequences of 115 healthy participants and developed a method to quantify the similarity between two number sequences on the basis of Damerau and Levenshtein's edit distance. "Same-author" and "different author" sequence pairs could be distinguished (96.5% AUC) based on 300 pseudo-random digits alone. We show that this phenomenon is driven by individual preference and inhibition of patterns and stays constant over a period of 1 week, forming a cognitive fingerprint.
FRBR. A Book History Perspective. Problems and Suggestions
Creators: name: Király, Péter
name: Káldos, János
Publisher: name: Zenodo
Year: 2022
Subjects: bibliographical data

description: The presentation was held during the Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data (October 12-14, 2022) organised by the Bibliographical Data Working Group of the DARIAH-ERIC.
description: The Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data has been supported by the DARIAH ERIC.
ETD-Student System Integration
Publisher: name: University of Virginia
Year: 2014
Subjects: innovation
student system
electronic dissertation
electronic thesis
ETD

description: Tie your ETD deposits to your Student Information System (SIS) for automatic fulfillment of graduation requirements. Changing your print deposit process? Take the opportunity to partner with your institutions registrar(s) to streamline administrative procedures as well. Students had to run all over campus to get receipts for dissertation completion tasks. Now they can submit from anywhere in the world and graduate on time, while providing open access to their scholarly output. It took a village to make this change and has very quickly made ETDs an integrated part of graduate program culture at our institution.
Additional file 2 of Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
Creators: name: Laversenne, Vanessa
name: Nazeeruddin, Sameer
name: Källstig, Emma C.
name: Colin, Philippe
name: Voize, Christel
name: Schneider, Bernard L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 2: Figure S2. Amyloid plaques in 5xFAD/AAV-tau mice: markers for microglia and neuritic pathology. Markers of microglia and neuritic pathology at the level of Aβ plaques in the hippocampus of 5xFAD/AAV-tau mice, 5 months after AAV-tau injection. a Representative three-dimensional confocal microscopy of an Aβ-positive neuritic plaque (4G8, in green) shows a microglial cell and processes (Iba1, in blue) positive for the CD68 lysosome marker (in red) in close contact with the Aβ deposit. The orthogonal view shows partial colocalization of CD68-positive vesicles and Aβ, indicating phagocytic activity. b–d Representative images of neuritic plaques (4G8 or 6e10, in green) surrounded by (b) LAMP1 immunoreactivity (red), c dystrophic presynaptic neurites (synaptophysin, in red), d human tau-positive dystrophic neurites (HT7, in red). e Gallyas silver staining (arrowheads) marks neuritic pathology surrounding Aβ plaques (*). Sections are co-stained with DAPI in blue (b–d) or with nuclear fast red (e). Scale bars: 10 µm (a) and 25 µm (b–e)
Transmission-phase of an electron in a quantum point contact
Creators: name: Lackenby, Bryce G. C.
name: Sushkov, Oleg P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: For the first time we calculate the electron transmission phase through a quantum point contact (QPC). The QPC is considered in the saddle point approximation in the single-electron picture. We show that when the electron energy is close to the height of the potential barrier the transmission-phase depends linearly on the energy. The coefficient in the linear dependence is logarithmically enhanced by the ratio of the height over the curvature of the barrier potential. We compare the calculated transmission phase with the first experimental measurements of the phase.
description: 4 pages, 3 figures
Selection and implementation of a Customer Relationship Management (CRM) program to track patron interactions
Publisher: name: University of Virginia
Year: 2014

description: Objectives: We sought to select a customer relationship management (CRM) tool in order to better track interactions with patrons and know where library connections in our clinical, research, and educational departments are strong or weak.

Methods: A requirements document was drafted, and several CRMs were identified as possible solutions. Four CRMs were tried by the authors of this paper, and the requirements matrix was updated after each trial. The authors reached a consensus, and a proposal was made to library management to beta-test Zoho CRM. The off-the-shelf product was then customized to meet the library's needs, and custom documentation was created to be used as a training aid for all librarians using the product.

Results: After beta-testing and a series of training sessions, the Zoho CRM was implemented in January 2014. Various reports were created to provide the necessary data to library administrators and outside organizations (Association of Academic Health Sciences Libraries/Association of Research Libraries). The database of information continues to grow on a daily basis. As it does, the ability to create richer interpretations of our data increases.

Conclusions: Throughout the process of selecting a CRM, we found that the commercially available systems were designed to track interactions and business processes in a much more thorough fashion than what our needs demand. The desire to have a perfect system was balanced with the desire to have something available quickly, and the Zoho CRM product has met the vast majority of our needs. However, as more libraries choose to track detailed information regarding patron interactions, there is room for a product tailored to libraries. Ideally, one library would create such a system and make it available in an open-source fashion.
title: Synthesis and Characterization of Novel Oligoazulenes with Mixed Ethynyl and Butadiynyl Bridges
Creators: name: Elwahy, Ahmed H. M.
name: Hafner, Klaus
Publisher: name: Wiley-VCH
Year: 2022

description: The new oligoazulenes 10–14 with mixed ethynyl and butadiynyl bridges were synthesized by oxidative Eglinton coupling from the readily accessible ethynylazulenes 3, 4, 7, 9 and 15 as well as by Pd/Cu-catalyzed cross-coupling reactions with the appropriate iodoazulenes 5, 6 and 8.
The mobilisation potential of anti-containment protests in Germany
Creators: name: Hunger, Sophia
name: Hutter, Swen
name: Kanol, Eylem
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Polarisation
subject: protest politics
subject: mobilisation
subject: Covid-19
subject: Germany
subject: 300 Sozialwissenschaften::320 Politikwissenschaft::320 Politikwissenschaft

description: The Covid-19 pandemic triggered polarisation across Europe. While most citizens supported governments’ containment measures, others took to the streets and voiced their dissatisfaction. The article focuses on the mobilisation potential related to this heterogenous protest wave. It examines individuals that show sympathy and are willing to engage in anti-containment demonstrations based on 16 waves of a rolling cross-section survey fielded in Germany in 2020/2021. The results show a considerable and stable mobilisation potential: every fifth respondent sympathises with the protesters, and around 60% of those are ready to participate themselves. Political distrust, far-right orientations and an emerging ‘freedom divide’ structure the potential, as do Covid-19-related economic and health threats. Moreover, the findings indicate a radicalisation process and show how ideology and threat perceptions drive the step from sympathy to willingness to participate, suggesting that ideological polarisation may quickly spill over to the streets given an appropriate supply of protest opportunities.
Getting In on the Ground Floor: Developing a Data Management Portal for Graduate Students
Year: 2013
Subjects: scholarly communication
poster
data management

description: As data management practices evolve, one major problem for the discipline of Data Curation lies in the education of students and faculty. Find out how the scientific data services unit of a research institution partnered with the university research office to create a Data Management Portal and see the model for content delivery developed through discussions with graduate students.
Additional file 1 of Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
Creators: name: Laversenne, Vanessa
name: Nazeeruddin, Sameer
name: Källstig, Emma C.
name: Colin, Philippe
name: Voize, Christel
name: Schneider, Bernard L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 1: Figure S1. Tau and Aβ pathologies in the 5xFAD/AAV-tau mouse model. a Representative images of the distribution of Aβ pathology (4G8, in green) and human tau (HT7, in red) throughout the hippocampus of 5xFAD/AAV-tau mice at 1.5 months and 6 months post-vector injection. * indicates the approximate site of AAV-tau injection. Scale bar: 1 mm. b Serial sections showing the distribution of Aβ pathology (4G8, in green) and human tau (HT7, in red) throughout the entire hippocampus, 5 months after AAV-tau injection. Coronal sections are shown from the most anterior (top left) to the most posterior (bottom right) regions of the hippocampus. The inter-section distance (200 µm) and the sections selected for immunohistochemical quantification (dashed rectangle) are shown in the most anterior part of the hippocampus. Note the extent of the hippocampal formation covered by human tau over-expression and the overlap of the tau and Aβ pathologies. *Indicates the approximate site of AAV-tau injection. Scale bar: 5 mm. c Immunohistochemistry for pathological forms of tau (in red) in the hippocampus of a representative 5xFAD/AAV-tau mouse: misfolded tau (MC1), Ser202/Thr205-phosphorylated tau (AT8), Ser396/Ser404-phosphorylated tau (PHF1). Note the overall somatodendritic localization, as well as differences in the distribution among the various tau species. Scale bar: 100 µm
Renal and hepatic function of patients with severe tricuspid regurgitation undergoing inferior caval valve implantation
Creators: name: Hewing, Bernd
name: Mattig, Isabel
name: Knebel, Fabian
name: Stangl, Verena
name: Laule, Michael
name: Stangl, Karl
name: Dreger, Henryk
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: tricuspid regurgitation (TR)
subject: TRICAVAL study
subject: caval valve implantation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Due to progressive abdominal-venous congestion severe tricuspid regurgitation (TR) is a common cause of cardiorenal and cardiohepatic syndrome. We initiated the TRICAVAL study to compare interventional valve implantation into the inferior vena cava (CAVI) versus optimal medical therapy (OMT) in severe TR. In the present subanalysis, we aimed to evaluate the effects of CAVI on clinical signs of congestion, renal and hepatic function. TRICAVAL was an investigator-initiated, randomized trial. Twenty-eight patients with severe TR were randomized to OMT or CAVI using an Edwards Sapien XT valve. Probands who completed the 3-month follow-up (CAVI [n = 8], OMT [n = 10]) were evaluated by medical history, clinical examination, and laboratory testing at baseline, 3 and 12 months. After 3 months, the CAVI group exhibited a significant reduction of body weight (from 80.7 [69.0-87.7] kg to 75.5 [63.8-84.6] kg, p < 0.05) and abdominal circumference (from 101.5 +/- 13.8 cm to 96.3 +/- 15.4 cm, p <= 0.01) and a trend to lower doses of diuretics compared to OMT. Renal and hepatic function parameters did not change significantly. Within a short-term follow-up, CAVI led to an improvement of clinical signs of venous congestion and a non-significant reduction of diuretic doses compared to OMT.
Patch individual filter layers in CNNs to harness the spatial homogeneity of neuroimaging data
Creators: name: Eitel, Fabian
name: Albrecht, Jan Philipp
name: Weygandt, Martin
name: Paul, Friedemann
name: Ritter, Kerstin
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Convolutional neural networks (CNNs)
subject: patch individual filters (PIF)
subject: spatial homogeneity of neuroimaging data
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Convolutional neural networks (CNNs)-as a type of deep learning-have been specifically designed for highly heterogeneous data, such as natural images. Neuroimaging data, however, is comparably homogeneous due to (1) the uniform structure of the brain and (2) additional efforts to spatially normalize the data to a standard template using linear and non-linear transformations. To harness spatial homogeneity of neuroimaging data, we suggest here a new CNN architecture that combines the idea of hierarchical abstraction in CNNs with a prior on the spatial homogeneity of neuroimaging data. Whereas early layers are trained globally using standard convolutional layers, we introduce patch individual filters (PIF) for higher, more abstract layers. By learning filters in individual latent space patches without sharing weights, PIF layers can learn abstract features faster and specific to regions. We thoroughly evaluated PIF layers for three different tasks and data sets, namely sex classification on UK Biobank data, Alzheimer's disease detection on ADNI data and multiple sclerosis detection on private hospital data, and compared it with two baseline models, a standard CNN and a patch-based CNN. We obtained two main results: First, CNNs using PIF layers converge consistently faster, measured in run time in seconds and number of iterations than both baseline models. Second, both the standard CNN and the PIF model outperformed the patch-based CNN in terms of balanced accuracy and receiver operating characteristic area under the curve (ROC AUC) with a maximal balanced accuracy (ROC AUC) of 94.21% (99.10%) for the sex classification task (PIF model), and 81.24% and 80.48% (88.89% and 87.35%) respectively for the Alzheimer's disease and multiple sclerosis detection tasks (standard CNN model). In conclusion, we demonstrated that CNNs using PIF layers result in faster convergence while obtaining the same predictive performance as a standard CNN. To the best of our knowledge, this is the first study that introduces a prior in form of an inductive bias to harness spatial homogeneity of neuroimaging data.
Constitución y origen de depósitos sedimentarios en una franja costera del N. W. de B. C. /
Creators: name: Alatorre Zamora, Miguel Angel
Publisher: name: Universidad Autónoma de Baja California.
Year: 2022
Subjects: subject: QE571 A538 1985

description: Se determinó el origen de los sedimentos arenáceos de arroyo, duna y playa de la zona comprendida entre Punta Cono y Punta Prieta, NW de Baja California, mediante un estudio de las asociaciones de minerales pesados, distribuidos en estos sedimentos, para lo cual se identificaron las especies mineralógicas.
FRBR, Library Catalogues, Bibliographies, or What Do We Need to Carry Out Research into Literature
Creators: name: Vimr, Ondřej
Publisher: name: Zenodo
Year: 2022
Subjects: bibliographical data

description: The presentation was held during the Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data (October 12-14, 2022) organised by the Bibliographical Data Working Group of the DARIAH-ERIC.
description: The Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data has been supported by the DARIAH ERIC.
Extracción e identificación de compuestos químicos de las gonadas de erizo de mar Strongylocentrotus franciscanus /
Creators: name: Lara Guadarrama, Juan Carlos
Publisher: name: Universidad Autónoma de Baja California.
Year: 2022
Subjects: subject: QL384 .E2 L37 1985

description: El erizo de mar strongylocentrotus franciscanus se recolectó en la localidad de Tres Hermanas en la Bahía de Todos Santos, Ensenada, Baja California.
Пути преодоления возможного энергокризиса в энергосистеме Украины
Creators: name: Владимировна, Шевченко Валентина
Publisher: name: Zenodo
Year: 2011
Subjects: электроэнергетика
энергосбережение
продление сроков эксплуатации

description: Опубликовано: [Шевченко В.В. Пути преодоления возможного энергокризиса в энергосистеме Украины // Материалы 3-й межвузовской научно-технической конференции преподавателей, молодых ученых и студентов "Энерго- и ресурсосберегающие технологии при эксплуатации машин и оборудования" (29-30.11.2011). - Украина, Донецк: Донецкий институт железнодорожного транспорта, 2011. - С. 9-10. https://doi.org/10.5281/zenodo.2535900]

Потребности в электроэнергии постоянно растут. Пути решения этой проблемы – увеличение выработки и энергосбережение.

Ключевые слова: электроэнергетика, энергосбережение, продление сроков эксплуатации.

Репозиторий НТУ "ХПИ" - открыть pdf
Changes in Cataloguing of Literary Works Related to the Introduction of National Library of Poland Descriptors
Creators: name: Pawlicki, Kamil
Publisher: name: Zenodo
Year: 2022
Subjects: bibliographical data

description: The presentation was held during the Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data (October 12-14, 2022) organised by the Bibliographical Data Working Group of the DARIAH-ERIC.
description: The Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data has been supported by the DARIAH ERIC.
Supplementary information for 'The influence of geochemical variation among Globigerinoides ruber individuals on paleoceanographic reconstructions'
Creators: name: Milton, James
name: Kearns, Lorna
name: Searle-Barnes, Alex
name: Foster, Gavin L
name: Standish, Christopher
name: Ezard, Thomas
Publisher: name: figshare
Year: 2023
Subjects: Climatology
Palaeoecology
Palaeontology (incl. palynology)

description: This file contains the .pdf version of the supplementary material related to 'The influence of geochemical variation among Globigerinoides ruber individuals on paleoceanographic reconstructions' including code chunks as well as supplementary figures and tables.
Additional file 3 of Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
Creators: name: Laversenne, Vanessa
name: Nazeeruddin, Sameer
name: Källstig, Emma C.
name: Colin, Philippe
name: Voize, Christel
name: Schneider, Bernard L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 3: Figure S3. Tau overexpression in the hippocampus increases the Aβ plaque number in female mice only. a Average size of the Aβ deposits (4G8 staining) in the ipsi- and contralateral hippocampus of 5xFAD/AAV-GFP and 5xFAD/AAV-tau mice. b Number of Aβ deposits (4G8 staining) per mm2 detected in the ipsi- and contralateral hippocampus in 5xFAD/AAV-GFP and 5xFAD/AAV-tau mice. In the right panel, the analysis is restricted to the entire hippocampus (ipsi and contra) of female mice only. Note the significant increase in the number of plaques in the AAV-tau injected group. Statistical analysis: unpaired two-tailed Student’s t-test, **p
Non-yrast spectra of odd-A nuclei in a model of coherent quadrupole-octupole motion
Creators: name: Minkov, N.
name: Drenska, S.
name: Drumev, K.
name: Strecker, M.
name: Lenske, H.
name: Scheid, W.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The model of coherent quadrupole and octupole motion (CQOM) is applied to describe non-yrast split parity-doublet spectra in odd-mass nuclei. The yrast levels are described as low-energy rotation-vibration modes coupled to the ground single-particle (s.p.) state, while the non-yrast parity-doublet structures are obtained as higher-energy rotation-vibration modes coupled to excited s.p. states. It is shown that the extended model scheme describes both the yrast and non-yrast quasi parity-doublet spectra and the related B(E1) and B(E2) transition rates in different regions of heavy odd-A nuclei. The involvement of the reflection-asymmetric deformed shell model to describe the single-particle motion and the Coriolis interaction on a deeper level is discussed.
description: 8 pages, 3 figures
Bibliographical Data. DARIAH-EU Working Group
Creators: name: Malínek, Vojtěch
name: Umerle, Tomasz
Publisher: name: Zenodo
Year: 2022
Subjects: bibliographical data

description: The presentation was held during the Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data (October 12-14, 2022) organised by the Bibliographical Data Working Group of the DARIAH-ERIC.
description: The Mutual Learning Workshop for Improving Cultural Heritage Bibliographical Data has been supported by the DARIAH ERIC.
A Modern Search for Wolf-Rayet Stars in the Magellanic Clouds: First Results
Creators: name: Massey, Philip
name: Neugent, Kathryn F.
name: Morrell, Nidia
name: Hillier, D. John
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Over the years, directed surveys and incidental spectroscopy have identified 12 Wolf-Rayet (WR) stars in the SMC and 139 in the LMC, numbers which are often described as "essentially} complete." Yet, new WRs are discovered in the LMC almost yearly. We have therefore initiated a new survey of both Magellanic Clouds using the same interference-filter imaging technique previously applied to M31 and M33. We report on our first observing season, in which we have successfully surveyed ~15$% of our intended area of the SMC and LMC. Spectroscopy has confirmed 9 newly found WRs in the LMC (a 6% increase), including one of WO-type, only the third known in that galaxy and the second to be discovered recently. The other eight are WN3 stars that include an absorption component. In two, the absorption is likely from an O-type companion, but the other six are quite unusual. Five would be classified naively as "WN3+O3 V," but such a pairing is unlikely given the rarity of O3 stars, the short duration of this phase (which is incommensurate with the evolution of a companion to a WN star), and because these stars are considerably fainter than O3 V stars. The sixth star may also fall into this category. CMFGEN modeling suggests these stars are hot, bolometrically luminous, and N-rich like other WN3 stars, but lack the strong winds that characterize WNs. Finally, we discuss two rare Of?p stars and four Of supergiants we found, and propose that the B[e] star HD 38489 may have a WN companion.
description: Astrophysical Journal, in press
Additional file 6 of Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology
Creators: name: Laversenne, Vanessa
name: Nazeeruddin, Sameer
name: Källstig, Emma C.
name: Colin, Philippe
name: Voize, Christel
name: Schneider, Bernard L.
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 6: Figure S6. mAb11 anti-Aβ antibody affects Aβ plaque size distribution. a Plaque size distribution as a percentage of the total number of Aβ-positive areas detected with the 4G8 antibody: yellow for plaques 1000 µm2. Areas below 10 µm2 were not considered as Aβ plaques. Note the significant increase in the fraction of plaques with a size > 500 µm2 following mAb11 treatment. Statistical analysis: Chi square test with control groups as expected distribution, and mAb11 group as observed distribution; control sham-treated 5xFAD/AAV-tau: n = 15 mice, mAb11-treated 5xFAD/AAV-tau: n = 16 mice. b Representative images of the masks after thresholding of the Aβ signal for size analysis. Note the presence of large size Aβ deposits with a compact shape (white *) in the mAb11-treated condition. DAPI staining is shown in blue. Scale bars: 100 µm
Un nouveau regard sur les épiciers-apothicaires parisiens (XIVe-XVIe siècle) : le manuscrit 17.939 de la Bibliothèque Royale de Belgique
Creators: name: Lafleur, Samantha
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2019
Subjects: Moyen-Âge
Apothicaires
Épiciers-apothicaires
Histoire
France
Études médiévales
Codicologie
Codicologie structurale

description: Cette thèse examine un manuscrit compilé par la communauté des épiciers-apothicaires de Paris vers le milieu du XVIe siècle. Une étude comparative du recueil, des documents lui étant contemporains et de l’historiographie de l’apothicairerie indique qu’il y a un décalage entre ces différentes sources d’information. Une déconstruction selon la méthode de la codicologie structurale et une analyse approfondie des textes ont permis de cerner la raison d’être du manuscrit et de mettre en lumière le discours du corps professionnel. Réponse à un contexte mouvementé, le codex donne la parole aux épiciers-apothicaires. Depuis le XIXe siècle, raconter l’histoire des apothicaires, c’est raconter l’histoire de la pharmacie. Cependant, le manuscrit de Bruxelles montre que si la pharmacie découle des activités autrefois pratiquées par les apothicaires, on ne peut pas affirmer que l’apothicaire médiéval était un pharmacien. La polyvalence du premier le différencie du second. Un examen codicologique du recueil montre que les activités de l’apothicairerie et celles de l’épicerie étaient étroitement imbriquées, bien que conflictuelles. Il est évident que les dynamiques de cette communauté socioprofessionnelle ont fluctué tout au long de son existence, comme en témoignent les différents moments de rédaction du manuscrit et l’évolution de ses statuts. Le discours établi par les épiciers-apothicaires accentue l’unité et la puissance du corps de métier. Toutefois, d’autres documents d’époque rappellent qu’il s’agit d’un portrait communautaire idéalisé. Afin de comprendre la raison d’être du recueil et les dynamiques de la communauté, j’ai placé le recueil dans son contexte historique par le biais d’une analyse historiographique et documentaire.
Negócios jurídicos processuais no processo penal
Creators: name: Oroso, Catharina Peçanha Martins
Publisher: name: Zenodo
Year: 2017
Subjects: Negócios jurídicos processuais
Direito Processual Civil
Direito Processual Penal
Autorregramento da vontade

description: O presente trabalho teve como objetivo analisar a aplicabilidade dos negócios jurídicos processuais no âmbito do Direito Processual Penal. Para tanto, foi necessário enfrentar quatro questões prévias e essenciais. A primeira, o estabelecimento das premissas metodológicas quanto ao autor regramento da vontade no processo e à Teoria Geral do Fato Jurídico para a adequada interpretação dos negócios jurídicos processuais. A segunda, o estudo propriamente dito das convenções processuais, analisando não só a sua evolução histórica, como também o seu regime jurídico segundo o Novo Código de Processo Civil (Lei nº 13.105/2015). A terceira, a distinção dos tipos de ação penal no ordenamento jurídico brasileiro, avaliando também o conceito e a natureza jurídica de ação penal. A quarta, já introdutória ao capítulo final, a existência de um diálogo salutar entre as codificações processual civil e penal e a interpretação extensiva e analógica segundo o art. 3º do Código de Processo Penal. Só então, pôde se proceder a um exame atento da possibilidade de aplicação dos negócios jurídicos processuais no Direito Processual Penal, observando-se não só a questão da consensual idade no Direito Público (indisponibilidade do direito, justiça penal negociada, a experiência dos Juizados Especiais Criminais e o instituto da colaboração premiada), como os fundamentos norteadores da aplicação. Passa-se à análise das hipóteses típicas de negociação previstas no sistema jurídico processual penal, bem assim com a constatação da aplicabilidade e o exame das possibilidades de uso das convenções processuais atípicas nas ações penais de iniciativa pública e privada. Encerra-se o estudo com considerações não exaustivas acerca dos requisitos e limites dos negócios jurídicos processuais no âmbito do Direito Processual Penal.