cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Optimal designs for nonlinear regression models with respect to non-informative priors
Creators: name: Burghaus, Ina
name: Dette, Holger
Publisher: name: Technische Universität Dortmund
Year: 2013
Subjects: subject: Bayesian optimality criteria
subject: canonical moments
subject: heteroscedasticity
subject: Jeffreys prior
subject: non-informative prior
subject: optimal design
subject: polynomial regression
subject: reference prior
subject: 310
subject: 330
subject: 620

description: In nonlinear regression models the Fisher information depends on the parameters of the model. Consequently, optimal designs maximizing some functional of the information matrix cannot be implemented directly but require some preliminary knowledge about the unknown parameters. Bayesian optimality criteria provide an attractive solution to this problem. These criteria depend sensitively on a reasonable specification of a prior distribution for the model parameters which might not be available in all applications. In this paper we investigate Bayesian optimality criteria with non-informative prior distributions. In particular, we study the Jeffreys and the Berger-Bernardo prior for which the corresponding optimality criteria are not necessarily concave. Several examples are investigated where optimal designs with respect to the new criteria are calculated and compared to Bayesian optimal designs based on a uniform and a functional uniform prior.
description: Discussion Paper / SFB 823;41/2013
Seeing sound : applications of sound visualization and mathematics in architectural design
Creators: name: Kim., Yeong Chul
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
For efficiency, tax energy
Creators: name: Frondel, Manuel
name: Vance, Colin
Publisher: name: Technische Universität Dortmund
Year: 2013
Subjects: subject: automobile travel
subject: instrumental variable approach
subject: rebound effect
subject: 310
subject: 330
subject: 620

description: Using household travel diary data collected in Germany between 1997 and 2012, we employ an instrumental variable (IV) approach to estimate fuel price and efficiency elasticities. The aim is to gauge the relative impacts of fuel economy standards and fuel taxes on distance traveled. We find that the magnitude of the elasticity estimates are statistically indistinguishable: higher fuel prices reduce driving by the same degree as higher fuel efficiency increases driving. This finding indicates an offsetting effect of fuel efficiency standards on the effectiveness of fuel taxation, calling into question the efficacy of the European Commission’s current efforts to legislate CO2 emissions limits for new cars given prevailing high fuel taxes.
description: Discussion Paper / SFB 823;42/2013
CP violation in the B system
Creators: name: Gershon, T.
name: Gligorov, V. V.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The phenomenon of CP violation is crucial to understand the asymmetry between matter and antimatter that exists in the Universe. Dramatic experimental progress has been made, in particular in measurements of the behaviour of particles containing the b quark, where CP violation effects are predicted by the Kobayashi-Maskawa mechanism that is embedded in the Standard Model. The status of these measurements and future prospects for an understanding of CP violation beyond the Standard Model are reviewed.
description: Invited review for Rep. Prog. Phys. v2 corresponds to published version
High-resolution SOFIA/EXES Spectroscopy of Water Absorption Lines in the Massive Young Binary W3 IRS 5
Creators: name: Li, Jialu
name: Boogert, Adwin
name: Barr, Andrew G.
name: DeWitt, Curtis
name: Rashman, Maisie
name: Neufeld, David
name: Indriolo, Nick
name: Pendleton, Yvonne
name: Montiel, Edward
name: Richter, Matt
name: Chiar, J. E.
name: Tielens, Alexander G. G.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present in this paper mid-infrared (5-8~$μ$m) spectroscopy toward the massive young binary W3~IRS~5, using the EXES spectrometer in high-resolution mode ($R\sim$50,000) from the NASA Stratospheric Observatory for Infrared Astronomy (SOFIA). Many ($\sim$180) $ν_2$=1--0 and ($\sim$90) $ν_2$=2-1 absorption rovibrational transitions are identified. Two hot components over 500 K and one warm component of 190 K are identified through Gaussian fittings and rotation diagram analysis. Each component is linked to a CO component identified in the IRTF/iSHELL observations ($R$=88,100) through their kinematic and temperature characteristics. Revealed by the large scatter in the rotation diagram, opacity effects are important, and we adopt two curve-of-growth analyses, resulting in column densities of $\sim10^{19}$ cm$^{-2}$. In one analysis, the model assumes a foreground slab. The other assumes a circumstellar disk with an outward-decreasing temperature in the vertical direction. The disk model is favored because fewer geometry constraints are needed, although this model faces challenges as the internal heating source is unknown. We discuss the chemical abundances along the line of sight based on the CO-to-H$_2$O connection. In the hot gas, all oxygen not locked in CO resides in water. In the cold gas, we observe a substantial shortfall of oxygen and suggest that the potential carrier could be organics in solid ice.
description: Accepted for publication in ApJ. 34 pages, 13 figures, and 14 tables. Comments are more than welcome!
Data optimizations for constraint automata
Creators: name: Jongmans, Sung-Shik T. Q.
name: Arbab, Farhad
Publisher: name: arXiv
Year: 2016
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Constraint automata (CA) constitute a coordination model based on finite automata on infinite words. Originally introduced for modeling of coordinators, an interesting new application of CAs is implementing coordinators (i.e., compiling CAs into executable code). Such an approach guarantees correctness-by-construction and can even yield code that outperforms hand-crafted code. The extent to which these two potential advantages materialize depends on the smartness of CA-compilers and the existence of proofs of their correctness. Every transition in a CA is labeled by a "data constraint" that specifies an atomic data-flow between coordinated processes as a first-order formula. At run-time, compiler-generated code must handle data constraints as efficiently as possible. In this paper, we present, and prove the correctness of two optimization techniques for CA-compilers related to handling of data constraints: a reduction to eliminate redundant variables and a translation from (declarative) data constraints to (imperative) data commands expressed in a small sequential language. Through experiments, we show that these optimization techniques can have a positive impact on performance of generated executable code.
title: ÐÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¸ ÑÑÑÐ´Ð½Ð¾ÑÑÐ¸ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð° ÐºÐ¸Ð½Ð¾ÑÑÐ±ÑÐ¸ÑÑÐ¾Ð² (Ð½Ð° Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ðµ Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ°)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð°ÐºÑÐ¾, ÐÐ¾Ð»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÑÐ±ÑÐ¸ÑÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð¿ÐµÑÐµÐ²Ð¾Ð´ ÑÑÐ±ÑÐ¸ÑÑÐ¾Ð²
Ð°ÑÐ´Ð¸Ð¾Ð²Ð¸Ð·ÑÐ°Ð»ÑÐ½ÑÐ¹ Ð¿ÐµÑÐµÐ²Ð¾Ð´
Ð¾Ð³ÑÐ°Ð½Ð¸ÑÐµÐ½Ð½ÑÐ¹ Ð¿ÐµÑÐµÐ²Ð¾Ð´
ÑÐµÑÐµÐ²Ð°Ñ ÐºÐ¾Ð¼Ð¿ÑÐµÑÑÐ¸Ñ
Ð¿ÑÐ°Ð³Ð¼Ð°ÑÐ¸ÐºÐ°
Ð´ÐµÐ¹ÐºÑÐ¸Ñ

description: ÐÐ°ÑÑÐ¾ÑÑÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ ÑÑÐ±ÑÐ¸ÑÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÐºÐ°Ðº Ð¾ÑÐ´ÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð²Ð¸Ð´Ð° Ð°ÑÐ´Ð¸Ð¾Ð²Ð¸Ð·ÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð°. Ð Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¸ Ð´Ð°ÑÑÑÑ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÐºÐ»ÑÑÐµÐ²ÑÐ¼ Ð´Ð»Ñ ÑÐ°Ð±Ð¾ÑÑ Ð¿Ð¾Ð½ÑÑÐ¸ÑÐ¼, Ð²ÑÐ´ÐµÐ»ÑÑÑÑÑ Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¸ Ð¿ÑÐ¸ÑÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ ÑÑÐ±ÑÐ¸ÑÑÐ¾Ð²Ð°Ð½Ð¸Ñ, Ð° ÑÐ°ÐºÐ¶Ðµ ÐµÐ³Ð¾ Ð¿ÑÐ¾ÑÑÑÐ°Ð½ÑÑÐ²ÐµÐ½Ð½Ð¾-Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð°Ñ Ð¾Ð³ÑÐ°Ð½Ð¸ÑÐµÐ½Ð½Ð¾ÑÑÑ. ÐÑÐ¾Ð±Ð¾Ðµ Ð²Ð½Ð¸Ð¼Ð°Ð½Ð¸Ðµ ÑÐ´ÐµÐ»ÑÐµÑÑÑ Ð²Ð¾Ð¿ÑÐ¾ÑÐ°Ð¼ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð° ÑÑÐ±ÑÐ¸ÑÑÐ¾Ð² Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð·Ñ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½ÑÑ Ð¿ÐµÑÐµÐ²Ð¾Ð´ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¸ÐµÐ¼Ð¾Ð² Ð¸ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¹ Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÑÐµÑÐ¸Ð°Ð»Ð¾Ð² Ð¸ ÐºÐ¸Ð½Ð¾ÑÐ¸Ð»ÑÐ¼Ð°. ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ Ð² ÑÐ°Ð¼ÐºÐ°Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¿Ð¾Ð¼Ð¾Ð³Ð°ÑÑ Ð¾Ð¿ÑÐµÐ´ÐµÐ»Ð¸ÑÑ ÑÑÐ´ Ð¿ÐµÑÐµÐ²Ð¾Ð´ÑÐµÑÐºÐ¸Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÑÐµÐ±ÑÑÑ Ð½Ð°ÑÑÐ½Ð¾Ð³Ð¾ Ð¾ÑÐ²ÐµÑÐµÐ½Ð¸Ñ, Ð¸ Ð¼Ð¾Ð³ÑÑ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÑÑÑ Ð¸Ð½ÑÐµÑÐµÑ Ð´Ð»Ñ Ð¿ÐµÑÐµÐ²Ð¾Ð´ÑÐ¸ÐºÐ¾Ð² Ð¸ Ð¿Ð¾ÑÐ»ÐµÐ´ÑÑÑÐ¸Ñ Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ð¹.
The acute effect of prolonged hamstrings vibration on the neuromuscular control in a single-leg drop landing task of ACLr patients
Creators: name: Yang, Jie (M.S. In Kinesiology)
name: 0009-0000-4206-158X
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Muscle onset time
ACLr
Hamstring vibration
EMG
Neuromuscular control

description: Abnormal neuromuscular control strategies persist for years after anterior cruciate ligament reconstruction (ACLr) and are risk factors for secondary injury. Prolonged hamstring vibration may affect neuromuscular control. The purpose of this study was to evaluate muscle onset time, burst duration during the Deceleration phase, time to peak activation, peak EMG amplitude, rate of EMG rise, and deceleration duration during the deceleration phase of a single-leg drop-landing task in ACLr patients before and after vibration. 5 ACLr participants (26.6±7yrs, time since surgery: 17±4months) participated. Kinetic, kinematic data, and electromyography of vastus lateralis (VL), vastus medialis (VM), rectus femoris (RF), semitendinosus (ST), biceps femoris long head (BFL), medial gastrocnemius (MG) and lateral gastrocnemius (LG) were collected during the task before and after the vibration. A paired t-test was used to compare differences before and after vibration. Muscle onset time was earlier after vibration for the Vastus Medialis (p=0.03) and Rectus Femoris (p= 0.03). No differences were observed in other muscles and other variables. In conclusion, prolonged hamstring vibration could modulate quadriceps neuromuscular control of ACLr patients, which may benefit lower limb mechanics and improve training efficiency.
An experimental assessment of visual attention and sign language comprehension in ADHD and neurotypical second language learners of American Sign Language
Creators: name: Joyce, Taylor Renee
name: 0009-0009-5946-6028
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Language learning
Sign language
Signed language
Second language learning
ADHD
Disability
Attention
Visual attention
Visual processing
Language acquisition

description: Sign language requires the perceiver’s visual attention, whether accessed in the foveal or peripheral vision; managing visual attention in real-world conversation is a skill second language (L2) sign learners may need practice to master. This task may be a challenge for an individuals with differences in visual attentional processing, such as those with ADHD, but little research on atypical signed L2 learners exists to date. This report introduces a novel online experiment to investigate visuo-attentional differences in hearing, L2 signers of American Sign Language while undergoing signed language comprehension. Participants attempt to rapidly perceive both linguistic and non-linguistic visual stimuli in their immediate and periphery vision while attending to a visual anchor. A small analysis of L2 signers finds a robust effect of the attentional manipulation (distance from stimulus to anchor), but conflicting evidence for sensitivity to linguistic factors such as sign complexity, sign frequency, and the difference between signed language and non-linguistic gestural stimuli. Importantly, this task is demonstrated to be successful at probing visuo-attentional mechanisms in a sign language processing context, and will be suitable for a test population between neurotypical and ADHD L2 ASL learners. Further, the results suggest that even somewhat experienced L2 signers may be relying on general perceptual, rather than specific linguistic, processes for sign and sign-like stimulus processing, which serves important implications for L2 signed language learners of all neurotypes.
title: ÐÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ðµ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Trados Ð¿ÑÐ¸ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ðµ ÑÐµÐºÑÑÐ¾Ð² ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÑÐ¸Ð»ÐµÐ¹
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐµÑÑÐ¾Ð²Ð°, ÐÑÐ¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¹ Ð¿ÐµÑÐµÐ²Ð¾Ð´
Ð¿Ð°Ð¼ÑÑÑ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð¾Ð²
SDL Trados Studio
CAT-Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ
Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐµ ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¿ÑÐ¸Ð½ÑÐ¸Ð¿Ñ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð½Ð¾Ð³Ð¾ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð°. ÐÐ°Ð½Ñ Ð¾Ð±ÑÐ¸Ðµ ÑÐ²ÐµÐ´ÐµÐ½Ð¸Ñ Ð¾ Ð¿Ð°Ð¼ÑÑÐ¸ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð¾Ð² Ð¸ ÐµÑ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ ÑÑÐ½ÐºÑÐ¸ÑÑ. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð° SDL Trados Studio. ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ Ð¿ÐµÑÐµÐ²Ð¾Ð´ ÑÐµÐºÑÑÐ¾Ð² ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÑ ÑÑÐ¸Ð»ÐµÐ¹ Ð² Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ðµ SDL Trados Studio Ñ Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ° Ð½Ð° ÑÑÑÑÐºÐ¸Ð¹ ÑÐ·ÑÐº, Ñ Ð¸ÑÐ¿Ð°Ð½ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ° Ð½Ð° ÑÑÑÑÐºÐ¸Ð¹ ÑÐ·ÑÐº. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ ÑÐ¾Ð¿Ð¾ÑÑÐ°Ð²Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð¾Ð². ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐ° ÐºÐ°ÑÐµÑÑÐ²Ð° Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð¾Ð², Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð½ÑÑ Ð² Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ðµ SDL Trados Studio.
The Berry-Keating operator on a lattice
Creators: name: Bolte, Jens
name: Egger, Sebastian
name: Keppeler, Stefan
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We construct and study a version of the Berry-Keating operator with a built-in truncation of the phase space, which we choose to be a two-dimensional torus. The operator is a Weyl quantisation of the classical Hamiltonian for an inverted harmonic oscillator, producing a difference operator on a finite, periodic lattice. We investigate the continuum and the infinite-volume limit of our model in conjunction with the semiclassical limit. Using semiclassical methods, we show that a specific combination of the limits leads to a logarithmic mean spectral density as it was anticipated by Berry and Keating.
Crafting and meaning : allusion, motif and identity in Australian jewellery and small-scale silver objects : a studio-based exploration
Creators: name: Hosking., Marian
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
"Offener Unterricht? Rechner?... Dafür bleibt keine Zeit...."
Creators: name: Barzel, Bärbel
Publisher: name: Gesellschaft für Didaktik der Mathematik
Year: 2005
Subjects: subject: 510

description: Der Titel drückt die Befürchtung vieler Lehrpersonen aus, dass mit neuen Unterrichtsmethoden, die dem Schüler und der Schülerin mehr Raum zur Eigenaktivität lassen, sowie der Integration von Rechnern in den Unterricht curriculare Vorgaben noch schwerer zu erreichen sind als ohne diese Innovationen. Verändern der Unterrichtsmethode und Rechnereinsatz werden als zeitliches Additivum empfunden, das zusätzlich belastet. Dagegen steht die Erfahrung von Lehrpersonen, die offenen Unterricht mit integriertem Rechnereinsatz nicht als Hürde sondern als besondere Chance erleben, inhaltliche und prozessuale Ziele gleichermaßen und gemeinsam in den Blick zu nehmen. Aufgrund dieser Erfahrungen ist im Rahmen des Lehrerfortbildungsprojekets T³ (Teachers Teaching with Technology) die Idee entstanden, Unterrichtsmaterial zu entwickeln, das exemplarisch für eine veränderte Unterrichtskultur mit integriertem Einsatz von Computeralgebrasystemen (CAS) stehen kann. Damit sollte an einem Beispiel ein Weg aufgezeigt werden, Öffnen von Unterricht und Medieneinsatz als Einheit zu begreifen mit dem Ziel, Mathematik und mathematische Tätigkeiten gleichermaßen im Unterricht erlebbar zu machen. So entstand Unterrichtmaterial zur Untersuchung ganzrationaler Funktionen (11. Jg), an dem Schülerinnen und Schüler sich über mehrere Wochen vielfältige Aspekte einer Funktionsuntersuchung selbstständig erarbeiten. Dies geschieht in Form einer "Lernwerkstatt", die im Rahmen des Forschungsprojektes MUKI (Mathematikunterricht zwischen Konstruktion und Instruktion) an der Universität Duisburg-Essen theoretisch reflektiert, weiterentwickelt und evaluiert wurde.
D1.5 - 1st Summary and Recording of Thematic Webinars Dedicated to Improving European Cooperation
Creators: name: EU-PolarNet 2 Consortium
name: Vieira, Gonçalo
Publisher: name: Zenodo
Year: 2022
Subjects: Webinars
EU Polar Cluster
EU-PolarNet 2
European Polar Board

description: Thematic webinars are one of the key communication formats within the strategy of EU-PolarNet 2 to foster cooperation at the European level. In 2021 the EU-PolarNet 2 organized six webinars, most in collaboration with the European Polar Board and the EU Polar Cluster. In order to increase visibility and impact, several webinars were presented in association to large events where different European and international stakeholders participated. These were the cases of the Arctic Science Ministerial 3 (April 2021), the All-Atlantic Conference 2022 (June 2021) and the UN COP26 (November 2021). The launch of the new EU Arctic Policy in 2021 provided an excellent framework to discuss the opportunities and needs for Arctic research and cooperation (November 2021). With the launch of the EU-PolarNet 2 call for service contracts, a novel contribution of the project, a webinar was also prepared for explaining the objectives and the application procedures (July 2021). With an internal focus on EU Polar Cluster projects, the impacts of COVID-19 on the members has been discussed, allowing to share best practices and to identify priority needs. The public webinars are available online, with links provided in the report.
Isometries, gaugings and N=2 supergravity decoupling
Creators: name: Antoniadis, Ignatios
name: Derendinger, Jean-Pierre
name: Petropoulos, P. Marios
name: Siampos, Konstantinos
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study off-shell rigid limits for the kinetic and scalar-potential terms os a single N=2 hypermultiplet. In the kinetic term, these rigid limits establish relations between four-dimensional quaternion-Kahler and hyper-Kahler target spaces with symmetry. The scalar potential is obtained by gauging the graviphoton along an isometry of the quaternion-Kahler space. The rigid limits unveil two distinct cases. A rigid N=2 theory on Minkowski or on AdS_4 spacetime, depending on whether the isometry is translational or rotational respectively. We apply these results to the quaternion-Kahler space with Heisenberg x U(1) isometry, which describes the universal hypermultiplet at type-II string one-loop.
description: 1+34 pages, Latex, v2: JHEP version
2D memristor reliability and modeling for neuromorphic computing
Creators: name: Huang, Yifu
name: 0000-0003-4385-7736
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Memristor
2D material
MoS₂
Resistive switching
Monte Carlo
Endurance
Yield
Reliability

description: Two-dimensional (2D) materials have been reported to exhibit non-volatile resistive switching (NVRS) phenomenon and applied on memristors or resistive random-access memory (RRAM) devices over the past few decades. Recent research further demonstrates the potential for 2D RRAM devices to be implemented in neuromorphic applications. However, reliability is a major challenge for practical application and industrialization. This dissertation presents the improvement of reliability in 2D material-based memristors and in-depth research in electrical characteristics, failure mechanisms, modeling, and neuromorphic applications. Chapter 2 discusses the reliability improvement of 2D monolayer MoS₂-based memristors by electron irradiation treatment. Sulfur vacancies, the density of which is modified by irradiation dosage, are revealed to be significant in the improvement of yield and endurance. Finite element analysis and Monte Carlo modeling are applied to help understand the role of sulfur vacancies in resistive switching and reliability improvement. In Chapter 3, further optimizations in reliability have been done by introducing sulfurization method in the preparation of MoS₂ films and the fine tune of metal deposition, extending the defect engineering from monolayer to multilayer MoS₂. Intriguing convergence of resistive switching metrics from the statistical measurements is highlighted along with the largely improved endurance performance. An effective switching layer model has been proposed to illustrate the underlying physics of endurance improvement and switching metrics convergence. In Chapter 4, a Monte Carlo modeling tool, which helps visualize the physical process and provides additional insight into the effective switching layer model, is discussed in detail. Transmission electron microscope (TEM) measurements provides experimental support to the model. In Chapter 5, pulse measurements of 2D ReSe₂-based memristors are discussed, demonstrating long-term potentiation and depression (LTP and LTD) behaviors in long-term plasticity programming. A Verilog-A model is proposed based on the multiple-step resistive switching behavior. Further, an artificial neural network (ANN) is trained based on the LTP/LTD parameters from experiments, showing the potential application of 2D memristors. In Chapter 6, the application of the constructed ANN model is discussed by investigating the temperature effect in TaOₓ-based memristors. The simulation results provide additional insights for the designs of potential hardware-based neuromorphic computing applications.
Factors Influencing Marketing Effectiveness Of The Real Estate Industry In Addis Ababa
Creators: name: Dessie, Aschalew
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2018

description: Real estate marketing is an exchange of economic and social structure people and groups satisfy their needs and wishes by constructing, supplying and interchanging real estate products and services. Thus, marketers of the industry should always understand the main factors that influence the real estate market. The main objective of this study is to investigate the key factors that influence the marketing effectiveness of the real estate companies operating in Addis Ababa. The study used both quantitative and qualitative research approaches and information gathered from both primary and secondary sources. It is made by taking samples of real estate customers from six pioneer and most experienced real estate companies selected among 380 operating in A.A using purposive sampling technique. The representatives of the study were taken from Addis Ababa and a total of 380 questionnaires were distributed and 365 were returned. But, during data cleaning 359 were valid and used for statistical analysis. And willing company managers from three of the selected companies are interviewed. The researcher applied descriptive statistics technique to analyze the data and data sorted coded, computed and analyzed using the statistical package for social science software (SPSS). The frequency, percentage, mean, standard deviation and graphic representations are made. By developing a conceptual model that contains five independent variables and one dependent variable this study tried to investigate the major factors that will influence the marketing effectiveness of the industry. It was hypothesized in this study that quality of homes, price fairness, brand reliability, location convenience, and sales person credibility significantly influence marketing effectiveness of the industry in Addis Ababa. The findings of the study showed that a positive and significant effect relationship between the dependent variable and all the independent variables
title: ÐÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð° ÑÐ»ÐµÐ½Ð³Ð° Ð² Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ð¸Ð¸ ÐÐ¶ÐµÑÐ¾Ð¼Ð° ÐÑÐ²Ð¸Ð´Ð° Ð¡ÑÐ»Ð¸Ð½Ð´Ð¶ÐµÑÐ° Â«ÐÐ°Ð´ Ð¿ÑÐ¾Ð¿Ð°ÑÑÑÑ Ð²Ð¾ ÑÐ¶Ð¸Â» (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÑÑÑÑÐºÐ¾Ð³Ð¾ Ð¸ Ð¸ÑÐ¿Ð°Ð½ÑÐºÐ¾Ð³Ð¾ ÑÐ·ÑÐºÐ¾Ð²)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: Ð¤ÐµÐ´Ð¾ÑÐ¾Ð²Ð°, Ð¯Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð»Ð¸Ð½Ð³Ð²Ð¸ÑÑÐ¸ÐºÐ°
ÑÐ»ÐµÐ½Ð³
Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¸Ð¹ ÑÐ·ÑÐº
Ð¸ÑÐ¿Ð°Ð½ÑÐºÐ¸Ð¹ ÑÐ·ÑÐº
ÑÑÑÑÐºÐ¸Ð¹ ÑÐ·ÑÐº
Ð¿ÐµÑÐµÐ²Ð¾Ð´

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð° ÑÐ»ÐµÐ½Ð³Ð° Ð² ÑÐ¾Ð¼Ð°Ð½Ðµ Ð.Ð. Ð¡ÑÐ»Ð¸Ð½Ð´Ð¶ÐµÑÐ° Â«ÐÐ°Ð´ Ð¿ÑÐ¾Ð¿Ð°ÑÑÑÑ Ð²Ð¾ ÑÐ¶Ð¸Â» Ð½Ð° ÑÑÑÑÐºÐ¸Ð¹ Ð¸ Ð¸ÑÐ¿Ð°Ð½ÑÐºÐ¸Ð¹ ÑÐ·ÑÐºÐ¸ (ÐºÐ°ÑÑÐ¸Ð»ÑÑÐºÐ¸Ð¹ Ð¸ Ð°ÑÐ³ÐµÐ½ÑÐ¸Ð½ÑÐºÐ¸Ð¹ Ð²Ð°ÑÐ¸Ð°Ð½ÑÑ). Ð ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐµ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÑÐµÑÐ¼Ð¸Ð½Ð° Â«ÑÐ»ÐµÐ½Ð³Â», Ð° ÑÐ°ÐºÐ¶Ðµ ÐµÐ³Ð¾ ÐºÐ»Ð°ÑÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸, Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ð° Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ð°ÑÐ¸ÐºÐ° Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð° ÑÐ»ÐµÐ½Ð³Ð° Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ ÑÑÐ½ÐºÑÐ¸Ð¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐ»ÐµÐ½Ð³ Ð²ÑÐ¿Ð¾Ð»Ð½ÑÐµÑ Ð² Ð°Ð½Ð³Ð»Ð¾ÑÐ·ÑÑÐ½Ð¾Ð¹ ÑÑÐ´Ð¾Ð¶ÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ Ð»Ð¸ÑÐµÑÐ°ÑÑÑÐµ. Ð Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð³Ð»Ð°Ð²Ðµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ ÑÐ¾Ð¿Ð¾ÑÑÐ°Ð²Ð¸ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð²ÑÑ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð¾Ð² ÑÐ¾Ð¼Ð°Ð½Ð° Ð½Ð° ÑÑÑÑÐºÐ¸Ð¹ ÑÐ·ÑÐº Ð¸ Ð´Ð²ÑÑ Ð¿ÐµÑÐµÐ²Ð¾Ð´Ð¾Ð² Ð½Ð° Ð¸ÑÐ¿Ð°Ð½ÑÐºÐ¸Ð¹ ÑÐ·ÑÐº.
title: Математические методы в психологии
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2021

description: В учебном пособии изложены теоретические основы математической обработки данных в психолого-педагогических исследованиях. Основное внимание сконцентрировано на особенностях использования отдельных анализов, методов обработки данных в программе STATISTICA, а также интерпретации результатов. Учебное пособие предназначено для студентов бакалавриата, обучающихся по направлению 37.03.01 «Психология», изучающих дисциплины «Математические методы в психологии», «Экспериментальная психология», «Психодиагностика».
title: ÐÐ½Ð³Ð»Ð¸Ð¹ÑÐºÐ¸Ð¹ ÑÐ·ÑÐº. ÐÐ²Ð¾Ð´Ð½Ð¾-ÐºÐ¾ÑÑÐµÐºÑÐ¸Ð²Ð½ÑÐ¹ ÐºÑÑÑ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ¾Ð½ÐµÑÐ¸ÐºÐ¸. Guide to English Pronunciation and Practical Phonetics
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¾Ð±Ð¾Ð´Ð¶Ð°Ð½Ð¾Ð²Ð°, ÐÐ¾Ð»Ð°
name: ÐÐ°Ð»ÑÐ½Ð¸ÑÐºÐ°Ñ, Ð.
name: ÐÐ°ÐºÐ°Ð·Ð½ÑÐº, Ð.
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2012
Subjects: Ð°Ð½Ð³Ð»Ð¸Ð¹ÑÐºÐ¸Ð¹ ÑÐ·ÑÐº
ÑÐ¾Ð½ÐµÑÐ¸ÐºÐ°
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: ÐÐ°Ð½Ð½Ð¾Ðµ ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¾ Ð½Ð° ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¸Ð½Ð¾ÑÐ·ÑÑÐ½Ð¾Ð¹ ÑÐ¾Ð½ÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹
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Activity time series of old stars from late F to early K VI. Exoplanet mass characterisation and detectability in radial velocity
Creators: name: Meunier, Nadège
name: Pous, Romain
name: Sulis, Sophia
name: Mary, David
name: Lagrange, Anne-Marie
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Stellar variability impacts radial velocities at various timescales and therefore the detectability of exoplanets and the mass determination based on this technique. It is necessary to implement systematic studies, to delineate the current limitations of RV techniques to detect Earth-like planets. This paper aims are to investigate whether the targeted 10% mass uncertainty from RV follow-up of transits detected by PLATO can be reached, and to analyse and quantify Earth-like planet detectability for various spectral types. We implemented blind tests based on a large data set of realistic synthetic time series reproducing different phenomena leading to stellar variability such as complex magnetic activity patterns as well as flows, covering F6-K4 stars and a wide range of activity levels. The 10% mass uncertainty for a 1 MEarth in the habitable zone of a G2 star cannot be reached, even with an improved version of a usual correction of stellar activity and even for long-duration (ten years) well-sampled observations. This level can be reached for masses above 3 MEarth or for K4 stars alone. We quantify the maximum dispersion of the RV residuals needed to reach this 10% level, assuming the correction method and models do not affect the planetary signal. Several other methods were tested and do not allow a significantly improvement of this limited performance. Similarly, such low-mass planets in the habitable zone cannot be detected with a similar correction: blind tests lead to very low detection rates for 1 MEarth and a very high level of false positives. Very significant and new improvements with respect to methods based on activity indicators to correct for stellar activity must be devised at all timescales to reach the objective of 10% uncertainty on the mass or to detect such planets in RV. Methods based on the correlation with activity indicators are unlikely to be sufficient.
description: Paper accepted in Astronomy and Astrophysics
A studio investigation of transcription for the formal development of figure painting
Creators: name: Harris., Joan
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Le Rôle des incubateurs et des accélérateurs dans le soutien aux femmes entrepreneurs : Une lecture du Programme Min Ajliki 2.0
Creators: name: BOUNJEM Tariq
name: LAGHRISSI Loubna
Publisher: name: Zenodo
Year: 2024

description: Bien que des progrès aient été réalisés, les femmes entrepreneures ne représentent que 10% du total des entreprises au Maroc, d'après les dernières données officielles du Haut-commissariat au plan, les études indiquent que les femmes rencontrent des obstacles lorsqu'elles lancent leur entreprise après avoir acquis une première expérience professionnelle, avec seulement 13% occupant des postes de direction pendant ces expériences. De plus, le faible taux de survie et de durabilité des nouvelles entreprises fondées par des femmes soulève des interrogations pertinentes sur l’écosystème entrepreneuriale et sur l'efficacité et l’efficience des politiques d'accompagnement et de soutien mises en place par l'Etat et les organisations non gouvernementales.

Les femmes entrepreneures jouent un rôle crucial dans la dynamique économique du pays, mais elles font face à de nombreux obstacles tout au long de leur parcours entrepreneurial, auxquels elles doivent courageusement faire face. Ces défis comprennent les difficultés d’asymétrie de l’information, à la formation, au marché et au financement, ainsi que les contraintes et les stéréotypes socio-culturelles qui entravent le développement des femmes dans la création et la promotion de leurs structures.

C'est pourquoi, un soutien entrepreneurial, aussi bien en amont de la création d'entreprise qu'en aval, reste essentiel pour garantir le succès de ses initiatives et favoriser la croissance à long terme des entreprises. Cela implique de fournir les ressources et les outils nécessaires ainsi que des conseils et un soutien adapté. Pour cela, il est pertinent de se poser la question suivante : « En quoi l'accompagnement offert par les incubateurs et les accélérateurs favorise-t-il le développement et la durabilité des entreprises fondées et dirigées par des femmes ?»
Naturalness made easy: two-loop naturalness bounds on minimal SM extensions
Creators: name: Clarke, Jackson D.
name: Cox, Peter
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The main result of this paper is a collection of conservative naturalness bounds on minimal extensions of the standard model by (vector-like) fermionic or scalar gauge multiplets. Within, we advocate for an intuitive and physical concept of naturalness built upon the renormalisation group equations. In the effective field theory of the standard model plus a gauge multiplet with mass $M$, the low scale Higgs mass parameter is a calculable function of $\overline{\rm MS}$ input parameters defined at some high scale $Λ_h > M$. If the Higgs mass is very sensitive to these input parameters, then this signifies a naturalness problem. To sensibly capture the sensitivity, it is shown how a sensitivity measure can be rigorously derived as a Bayesian model comparison, which reduces in a relevant limit to a Barbieri--Giudice-like fine-tuning measure. This measure is fully generalisable to any perturbative EFT. The interesting results of our two-loop renormalisation group study are as follows: for $Λ_h=Λ_{Pl}$ we find "$10\%$ fine-tuning" bounds on the masses of various gauge multiplets of $M
description: 31 pages, 9 figures; v2: version published in JHEP
Repurposing niclosamide : oral and inhaled delivery of niclosamide using hot-melt extrusion and thin film freezing technologies
Creators: name: Jara Gonzalez, Miguel Orlando
name: 0000-0002-2568-8660
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Drug repurposing
Drug metabolism
Animal models
Clinical trials
Routes of administration
Dosage forms
Pharmacokinetics
Hot-melt extrusion
Amorphous solid dispersions
Nanoparticles
Niclosamide
Pulmonary administration
Thin film freezing
Dry powder inhaler
SARS-CoV-2 enteric capsules
Enteric-coated tablet
Amorphous nanoparticles
Liquid–liquid phase separation
Biorelevant media

description: This research aims to enable the repurposing of niclosamide as a viable pharmaceutical product for treating cancer and viral infections, including COVID-19. Niclosamide is a unique drug candidate because although it was approved for use over 60 years ago as an anthelmintic medication, several studies have shown its potential as a multi-targeted cancer therapy, broad-spectrum antiviral (including COVID-19), and antibacterial, among several others. There have previously been several attempts to repurpose niclosamide in clinical trials. Unfortunately, niclosamide is a poorly water-soluble molecule with low bioavailability, which has negatively affected the outcomes of these studies. To overcome this challenge, we developed two different niclosamide formulations based on the targeted disease state as well as the intended route of administration. We prepared an amorphous solid dispersion of niclosamide (Niclosamide ASD) as an oral therapy for prostate cancer and a dried powder inhaler to treat COVID-19 infection. Niclosamide ASD was manufactured using hot-melt extrusion. This ASD generates nanoparticles during its dissolution, increasing niclosamide’s apparent 5 solubility by more than 60-fold (i.e. from 6.6 ± 0.4 to 481.7 ± 22.2 μg/mL) and its oral bioavailability in Sprague–Dawley rats. This formulation generates amorphous nanoparticles during its dissolution, confirmed by cryo-TEM and Wide-angle X-ray scattering. Nevertheless, niclosamide ASD undergoes recrystallization in acidic media, and an enteric oral dosage form of niclosamide ASD was formulated without hindering the generation of nanoparticles while maintaining the increase in the niclosamide’s apparent solubility. The formulation successfully increased niclosamide’s plasma levels in dogs when compared to a niclosamide solution prepared using organic solvents. Niclosamide dried powder inhaler was prepared using the Thin Film Freezing technology (TFF). This formulation proved to be safe after an acute three-day, multi-dose pharmacokinetic study in rats, as evidenced by histopathology analysis. In addition, it achieved lung concentrations above the required IC90 levels of SARS-CoV-2 for at least 24 h after a single administration in Syrian golden hamsters. Efficacy studies confirmed that the formulation effectively reduces viral load in infected hamsters that had been inoculated 24 hours prior with intranasal SARS-CoV-2. This formulation was transferred to a pharmaceutical company and has successfully completed phase 1 clinical trials.
Sieben Stolpersteine - vernachlässigte Bedingtheiten jeder Schulreform
Creators: name: Bauersfeld, Heinrich
Publisher: name: Gesellschaft für Didaktik der Mathematik
Year: 2005
Subjects: subject: 510

description: Im Sinne von Luhmanns Beobachter 2.Ordnung wird versucht, ein Resümee aus mehr als 50 Jahren Beteiligung (und Mitschuld) an der Entwicklung zu ziehen. Dabei ergeben sich sieben grundlegende Hindernisse, die in der gegenwärtig erneut intensivierten öffentlichen Diskussion um die Reform von Schule und Unterricht kaum Berücksichtigung finden. In der Folge lässt sich die faktische Wirkungslosigkeit wenn nicht Schädlichkeit auch der jüngsten politischen bzw. verwaltungsmäßigen Entscheidungen, von der Schulorganisation bis zu den Standards, vermuten. Stolpersteine sollen hier die auf dem Wege oft übersehenen kleinen Ursachen für Unfälle oder gar für ein Abbrechen und die Erfolglosigkeit der Absichten bezeichnen. Anders als die echten Kiesel sind diese Steine untereinander mehr oder weniger verbunden und daher nicht trennscharf darstellbar.
“I am not a princess”: Navigating Mana Wahine in Disney’s Moana
Creators: name: Hyland, Nicola
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2023
Subjects: classificationCode: 3602
subject: Creative and professional writing
classificationCode: 3606
subject: Visual arts
classificationCode: 3604
subject: Performing arts
classificationCode: 3601
subject: Art history, theory and criticism

description: Moana is a Disney heroine like no Other¾ a protofeminist South Seas protagonist who is neither princess, nor fairy, but an assertive, young, female leader. She embodies critical traits of mana wahine, while quashing myths about the subservience and sexualisation of young brown women.The representation of the Disney character Moana has been critically (and ironically) overshadowed by the 2016 film’s contentious representation of pan-Polynesian deity, Maui. Drawing on the Māori feminist discourse of mana wahine, this essay considers how Moana, while only two-dimensional, signifies an alternative and empowering performativity for Oceanic women. I argue that in shifting the contentious alignment of Oceanic female bodies with the land to an affinity with the ocean, the film offers a useful counter-trope to the passive dusky maiden. This analysis is self-reflexive; unpacking the particular looking relations of a contemporary bicultural feminist and how an “educated” response to this text was unsettled by unexpected affect.
The Origin of Star Formation in Early-type Galaxies Inferred from Spatially Resolved Spectroscopy
Creators: name: Lee, Yun Hee
name: Hwang, Ho Seong
name: Hwang, Narae
name: Lee, Jong Chul
name: Kim, Ki-Beom
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the origin of star formation activity in early-type galaxies with current star formation using spatially resolved spectroscopic data from the Mapping Nearby Galaxies at APO (MaNGA) in the Sloan Digital Sky Survey (SDSS). We first identify star-forming early-type galaxies from the SDSS sample, which are morphologically early-type but show current star formation activity in their optical spectra. We then construct comparison samples with different combinations of star formation activity and morphology, which include star-forming late-type galaxies, quiescent early-type galaxies and quiescent late-type galaxies. Our analysis of the optical spectra reveals that the star-forming early-type galaxies have two distinctive episodes of star formation, which is similar to late-type galaxies but different from quiescent early-type galaxies with a single star formation episode. Star-forming early-type galaxies have properties in common with star-forming late-type galaxies, which include stellar population, gas and dust content, mass and environment. However, the physical properties of star-forming early-type galaxies derived from spatially resolved spectroscopy differ from those of star-forming late-type galaxies in the sense that the gas in star-forming early-type galaxies is more concentrated than their stars, and is often kinematically misaligned with stars. The age gradient of star-forming early-type galaxies also differs from those of star-forming late-type galaxies. Our findings suggest that the current star formation in star-forming early-type galaxies has an external origin including galaxy mergers or accretion gas from the cosmic web.
description: 19 pages, 12 figures, Accepted for publication in ApJ
Catastrophes in non-equilibrium many-particle wave functions: universality and critical scaling
Creators: name: Mumford, J
name: Kirkby, W
name: O'Dell, D H J
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: As part of the quest to uncover universal features of quantum dynamics, we study catastrophes that form in simple many-body wave functions after a quench, focusing on two-mode systems that include the two-site Bose Hubbard model, and under some circumstances optomechanical systems and the Dicke model. When the wave function is plotted in Fock space plus time certain characteristic structures generically appear that we identify as cusp caustics. In the vicinity of such a catastrophe the wave function takes on a universal form described by the Pearcey function and obeys scaling relations which depend on the total number of particles $N$. In the thermodynamic limit ($N \rightarrow \infty$) the cusp becomes singular, but at finite $N$ it is decorated by an interference pattern. This pattern contains an intricate network of vortex-antivortex pairs, initiating a theory of topological structures in Fock space. In the case where the quench takes the form of a $δ$-kick we show how to analytically map the wave function onto the Pearcey function and hence obtain the scaling exponents for the size and position of the cusp, as well as those for the amplitude and characteristic length scales of its interference pattern.
description: 16 pages, 8 figures
Individual differences in responses to moral dilemmas
Creators: name: Luke, Dillon Mathew
Publisher: name: The University of Texas at Austin
Year: 2023
Subjects: Morality
Moral judgment
Moral dilemmas
Utilitarianism
Individual differences
Personality

description: Considerable research in moral psychology has provided evidence for disagreement in the resolution of moral dilemmas pitting the greater good against adherence to moral norms. One potential explanation for this disagreement lies in stable individual differences between people, which has been supported by past research suggesting that differences in moral-dilemma judgments are stable over time and related to individual differences in cognition, emotion, antisocial traits, and beliefs and attitudes. While past research is informative, traditional measurement of moral-dilemma judgment confounds the influence of several factors, rendering the meaning of disagreement in moral-dilemma judgments ambiguous. To address these limitations, the purpose of this dissertation was to provide more nuanced insights into disagreement in moral-dilemma judgments by using the CNI model of moral decision-making to separately quantify sensitivity to consequences, sensitivity to moral norms, and general preference for inaction versus action in responses to moral dilemmas. Across three lines of research, the current work examined (1) the temporal stability of individual differences in the three factors (Article 1) and (2) relations between individual differences in the three factors and basic personality traits (Article 1), political ideology (Article 2), and facet-level psychopathy (Article 3). Findings from Article 1 provided evidence for high stability in sensitivity to consequences and sensitivity to moral norms, which was comparable to that of the Big Five personality traits, but lower stability in general preference for inaction versus action. Findings across Articles 1-3 revealed an unexpectedly strong contribution of basic personality traits to disagreement through relations with all three factors (Article 1), an unexpectedly weak contribution of political ideology to disagreement through sensitivity to consequences (Article 2), and an expectedly strong contribution of interpersonal and affective psychopathic traits to disagreement through sensitivity to moral norms (Article 3). Together, these findings have important implications for theories of moral judgment and provide a novel theoretical framework for understanding disagreement in moral-dilemma judgments, which may be used to develop tailored interventions to reduce real-world disagreement.