cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation of the chemical composition and antioxidant activity of extracts and fractions of Ocotea notata (Ness) Mez (Lauraceae)
Creators: name: Rafaella Velloso Pereira
name: Mecenas, Anete Souza
name: Malafaia, Camila R. Adão
name: Amaral, Ana Claudia. F.
name: Muzitano, Michelle Frazão
name: Simas, Naomi Kato
name: Leal, Ivana Correa Ramos
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: The specie Ocotea notata (Nees & Mart). Mez is a tree with 5 meters high, that can be found in restinga regions in the Brazilian coast. This study describes a phytochemical investigation, total phenolic content and the antioxidant activity of extracts and fractions by DPPH and ORAC. Phenolic content revealed equivalent concentration between evaluated samples, similar to found in the leave extract (66.4 mEq GA/g). By DPPH, extracts and fractions showed effective concentration (EC50) lower than the standards Ginkgo biloba 761® (23.60 ± 0.64 µg/ml) and quercetin (6.06 ± 0, 92 µg/mL); for the ORAC method, ethyl acetate partition showed a value of 2.06 mmol Trolox equivalent g−1 better than obtained in Ginkgo biloba (1.03 ± 0.25 mmol.Trolox equivalent g−1. The butanol partition (0.52 mmol.Trolox equivalent g−1) and the aqueous residue (0.74 mmol Trolox equivalent g−1) have a lesser ORAC potential than ethyl acetate partition. The butanolic partition, investigated by LC-DAD-MS/MS and QTOF-MS, revealed six major compounds: miquelianin (1), isoquercitrin (2), quercitrin (3), kaempferol-3-O-pentose (4), afzelin (5) and isorhamnetin-glucuronide (6).
Chemical constituents of the aerial parts of Salvia judaica Boiss. from Jordan
Creators: name: Al-Qudah, Mahmoud A.
name: Tashtoush, Hasan I.
name: Ethar F. Khlaifat
name: Ibrahim, Sahar O.
name: Saleh, Ayman M.
name: Al-Jaber, Hala I.
name: Zarga, Musa H. Abu
name: Orabi, Sultan T. Abu
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Inorganic Chemistry
subject: Hematology

description: Investigation of the chemical constituents of Salvia judaica growing wild in Jordan led to the isolation and identification of 15 known compounds. These included: luteolin-3′-methyl ether (1), indole-3-carboxyaldehyde (2), p-hydroxybenzaldehyde (3), tricin (4), apigenin (5), methyl isoferuloyl-7-(3,4-dihydroxyphenyl) lactate (6), methyl rosmarinate (7), rosmarinic acid (8), salvigenin (9), β-sitosterol (10), 3β, 28-dihydroxyurs-12-ene (11), cirsilineol (12), 2,3-dihydroxyurs-12-en-28-oic acid (13), β-sitosteryl glucoside (14), and tormentic acid (15). Compounds 6 and 7 exhibited strong radical scavenging and chelating activities as compared to α-tocopherol and ascorbic acid, compound 7 showed a 2-fold greater antioxidant activity as compared to compound 6. Furthermore, low doses of compounds 6 and 7 were able to inhibit the growth of leukemic (HL-60, Jurkat, K562 and CCRF-SB) and solid tumor cells (MCF-7, MDA-MB-231 and Caco-2). Compound 7 showed a ca. 3–4-fold stronger cytotoxicity against the tested cells as compared to compound 6.
Mycenolide A, new butenolide from a marine sediment-derived bacterium Streptomyces sp. 4054
Creators: name: Oliveira, Josiane A. Monteiro De
name: Williams, David E.
name: Andersen, Raymond J.
name: Sarragiotto, Maria H.
name: Baldoqui, Debora C.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: Streptomyces sp. 4054, isolated from marine sediments, produced a new butenolide, mycenolide A (1), along with five known butenolide derivatives (2–6). The structures of the compounds were established based on 1D- and 2D-NMR spectroscopic analysis, circular dichroism, and mass spectrometry data. The antimicrobial activity of the crude extract of the marine bacteria Streptomyces sp. 4054 was evaluated, showing good results against Bacillus subtilis and MRSA.
L'alignement des auteurs HAL sur IdRef dans un projet sur les notices d'autorité de type "enseignants-chercheurs"
Creators: name: Potier, Florent
Publisher: name: Zenodo
Year: 2022
Subjects: IdRef
ORCID ID
IdHAL
Identifiants chercheurs

description: Présentation réalisée lors de la Journée d’étude « Les autorités étoilées » (24 mai 2022), organisée par l'ABES, et consacrée aux actions d’enrichissement de la qualité des données d'autorités
Genome-wide appraisal of loss-of-function variants in Zea mays
Creators: name: Zhengbin Liu
name: Bottoms, Christopher
name: Flint-Garcia, Sherry
name: McMullen, Michael
Publisher: name: F1000 Research Limited
Year: 2018

description: In the maize HapMap2 project (Chia et al. 2011) 55 million single nucleotide polymorphisms were identified in 103 lines representing domesticated Zea mays and its wild relatives.  One of the striking findings of that study was that 7.5% of the 20,380 high-confidence genes exhibited in one or more lines SNPs for premature stop codon (nonsense) variation as compared to B73.  As expected the frequency of nonsense mutations was greater in teosinte  inbred lines (TILs) than in improved maize inbreds with a longer history of inbreeding.  Among the lines sequenced in the HapMap2 project are the founders of the nested association mapping (NAM) population (McMullen et al. 2009).  During the development and characterization of the NAM population it was noted that residual heterozygosity was higher in low recombination regions of the genome.  The authors ascribed this phenomenon to the Hill-Robertson effect that predicts selection is less effective on alleles in repulsion in regions of limited recombination.  This study follows up these two observations: 1) For the NAM founders and TILs, the original HapMap2 sequence reads were used to call a broader range of loss of function (LoF) variation to include nonsense, start-loss, splice-site and small insertion/deletions that would result in frame-shift variation.  Traditionally, LoF variants are regarded as rare and are of considerable scientific and clinical interest in the medical sciences. In the crop sciences, specific rare alleles have been reported that associate with grain size and yield.  However, systematic analysis to understand the role LoF variants in agronomic traits in crop plants is lacking.  2)  The distribution of LoF variation were mapped across the genome and relationship between LoF variation and recombination examined.
Astrernestin, a novel aurone-phenylpropanoid adduct from the roots of Astragalus ernestii
Creators: name: Li, Jin-Qiang
name: Chao-Jiang Xiao
name: Ye-Meng Li
name: Tian, Xin-Yan
name: Dong, Xiang
name: Jiang, Bei
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Astragalus ernestii has been used as a substitute for Radix Astragali (Huang-Qi) in southwest China. To better understand the chemical rationale for the medicinal usage, the phytochemistry of A. ernestii was recently studied. As a result, a novel aurone-phenylpropanoid adduct astrernestin (1), together with five known phenoloids calycosin-7-O-β-D-glucopyranoside (2), 4,4′-dimethoxy-3′-hydroxy-7,9′:7′,9-diepoxylignan-3-O-β-D-glucopyranoside (3), syringaresinol-4-O-β-D-monoglucoside (4), hedyotol D 4″-O-β-D-glucopyranoside (5) and trifolirhizin (6), were isolated from the roots of A. ernestii. The structure of compound 1 was elucidated by extensive spectroscopic analysis and optical rotation calculation.
Identification of a new β–carboline from cyanobacterium Lyngbya sp. TAS07
Creators: name: Dashti, Yousef
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Inorganic Chemistry

description: Metabolic profiling of an extract of cyanobacterium Lyngbya sp. TAS07 revealed evidence of a new secondary metabolite along with a known compound 1-hydroxymethyl-β-carboline (1). Structure of new natural product 9-hydroxy-1-hydroxymethyl-β-carboline (2) was elucidated based on HR-MS data and detailed analysis of one and two-dimensional NMR spectra.
O juiz não joga aos dados, A propósito de uma conferência de Dominik Richers, Rechtslast – Lastregeln als Mittel der Überwindung von Zweifeln in der Rechtsanwendung, 2017
Creators: name: Neuner, Jörg
Publisher: name: Católica Law Review
Year: 2022

description: Católica Law Review, v. 6 n. 2 (2022): Direito privado
The use of the headspace single drop microextraction and microwave distillation for determination of essential oil components of Salvia hydrangea DC
Creators: name: Piryaei, Marzieh
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: A simple microwave distillation was used in order to prevent the traditional prolonged hydrodistillation. To this end, the volatile compounds in aerial sections of Salvia hydrangea DC were analyzed. Then, headspace single drop micro-extraction (HS–SDME) was done that was connected to gas chromatography–mass spectrometry (GC–MS). Following irradiation, the volatile components of headspace were gathered through an n-heptadecane single drop. The relative peak areas, which were used as the index, optimized the conditions of extraction. The indexes of retention and mass spectra were used for confirmation of chemical configuration in the extracts of HS–SDME.
Limites à duração do tempo de trabalho e cumulação de contratos de trabalho – Anotação ao Acórdão do TJUE de 17 de Março de 2021, Academia de Studii Economice din Bucaresti c. Organismul
Creators: name: Carvalho, António Nunes De
Publisher: name: Católica Law Review
Year: 2022

description: Católica Law Review, v. 6 n. 2 (2022): Direito privado
IMPACT OF PROJECT-BASED LEARNING AND SELF-EFFICACY ON MATHEMATICS PEDAGOGICAL CONTENT KNOWLEDGE OF PROSPECTIVE TEACHERS
Creators: name: DEANE UMBOH
name: MOHAMAD SYARIF SUMANTRI
name: YURNIWATI YURNIWATI
Publisher: name: Zenodo
Year: 2024
Subjects: Mathematics Pedagogical Content Knowledge; Project-Based Learning; Self-Efficacy.

description: Abstract

Educators are recommended to prioritize the enhancement of prospective teachers' mathematics pedagogical content knowledge (MPCK). Therefore, this study aimed to investigate impact of project-based learning (PjBL) and self-efficacy on MPCK of prospective teachers. It was conducted during the 2023/2023 academic year in Manado, Indonesia, using a quasi-experimental study design. The experimental group was subjected to PjBL, and traditional method was adopted for the control group. MPCK data were collected through essay and performance tests, while self-efficacy was assessed using a 5-point Likert Scale. Subsequently, the data were analyzed using two-way ANOVA. The results showed that (1) Prospective teachers who engaged in PjBL had higher MPCK abilities compared to those subjected to traditional method, (2) There was an interaction between learning methods and self-efficacy, (3) Prospective teachers with high self-efficacy had higher MPCK abilities when subjected to PjBL than traditional method, and vice versa. In conclusion, self-efficacy played a crucial role in the implementation of PjBL for developing knowledge and pedagogical abilities of prospective teachers.
Algrizea Minor Sobral, Faria & Proença (Myrteae, Myrtaceae): chemical composition, antinociceptive, antimicrobial and antioxidant activity of essential oil
Creators: name: Veras, Bruno Oliveira De
name: Yago Queiroz Dos Santos
name: Oliveira, Fernanda Granja Da Silva
name: Almeida, Jackson Roberto Guedes Da Silva
name: Silva, Alexandre Gomes Da
name: Correia, Maria Tereza Dos Santos
name: Diniz, Katharina Marques
name: Oliveira, João Ricardhis Saturnino De
name: Lima, Vera Lúcia De Menezes
name: Navarro, Daniela Maria Do Amaral Ferraz
name: Aguiar, Júlio César Ribeiro De Oliveira Farias De
name: Oliveira, Maria Betânia Melo De
name: Lopes, Ana Catarina De Souza
name: Silva, Márcia Vanusa Da
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified

description: This work aimed to investigate the chemical composition, antimicrobial, antinociceptive, acute toxicity and antioxidant activity of the essential oil of Algrizea minor (EOAm). The essential oil presented as the major constituents β-Pinene (56.99%), α-Pinene (16.57%), Germacrene D (4.67%), Bicyclogermacrene (4.66%), (E)-Caryophyllene (3.76%) and Limonene (1.71%). It was verified that the essential oil did not show acute toxicity in the maximum dose of 5,000 mg/kg. In the evaluation of the antinociceptive activity it was verified that the essential oil reduced in 65.84% the number of writhing in the mice, reducing the pain in 59.17%, and the mechanism of action in pain reduction was opioid, similar to morphine. The essential oil also presented significant antimicrobial against Gram positive and Gram-negative bacteria and fungi, and the antioxidant activity was relevant. Therefore, these results demonstrate the great potential for the future development of pharmaceutical products with the essential oil of Algrizea minor (EOAm).
Three new muurolane-type sesquiterpene glycosides from the whole plants of Balanophora fungosa subsp. indica
Creators: name: Bui Huu Tai
name: Nguyen Xuan Nhiem
name: Pham Hai Yen
name: Quang, Tran Hong
name: Nguyen Thi Cuc
name: Trang, Do Thi
name: Doan, Vu Van
name: Hang, Dan Thi Thuy
name: Minh, Chau Van
name: Kiem, Phan Van
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Three new muurolane type sesquiterpene glycosides, named balanoindicosides A − C (1 − 3), were isolated from the whole plant of Balanophora fungosa subsp. indica using various chromatographic methods. Their structures were determined by extensive analysis of HR-ESI-MS and NMR spectroscopy. The stereochemistry of muurolane sesquiterpene backbone was demonstrated by NOESY analysis. Configuration of C-12 in compounds 2 and 3 could be distinguished by chemical shift value of C-14. Compounds 1-3 exhibited weak cytotoxic activity towards HepG-2, HL-60, LU-1, and MCF-7 cell lines.
Floating charges in Scotland: lessons from a mixed legal system
Creators: name: MacPherson, Alisdair D. J.
Publisher: name: Católica Law Review
Year: 2022

description: The floating charge is a complicated form of security interest that is most associated with English law. However, in 1961 a statutory floating charge was introduced in Scotland, as a modified version of the English floating charge. Despite their popularity in practice, there have been considerable difficulties integrating floating charges into wider Scots law in subsequent decades. Scotland has a mixed legal system and its property law is principally Civilian. As such, it can be a useful system to study regarding the transmission of floating security from one type of system to another. The Scottish experience can provide some valuable lessons for others considering similar reforms. To help identify these lessons, this article examines various facets of floating charges in Scotland: concepts and terminology, creation of floating charges, “crystallisation”, the relationship with property law, ranking and enforcement.
description: Católica Law Review, v. 6 n. 2 (2022): Direito privado
On the construction of unbiased estimators for the group testing problem
Creators: name: Haber, Gregory
name: Malinovsky, Yaakov
Publisher: name: Maryland Shared Open Access Repository
Year: 2018
Subjects: Binomial sampling plans
Group testing
Multinomial sampling plans
Sequential estimation
Unbiased estimation

description: Debiased estimation has long been an area of research in the group testing litera-ture. This has led to the development of many estimators minimizing bias and, most recently, an unbiased estimator based on sequential binomial sampling. Previous research, however, has focused heavily on the simple case where no misclassiﬁcation is assumed and only one trait is to be tested. In this paper, we consider the problem of unbiased estimation in these broader areas, giving constructions of such estimators for several cases. We show that, out-side of the standard case addressed previously in the literature, it is impossible to ﬁnd any proper unbiased estimator, that is, an estimator giving only values in the parameter space. This is shown to hold generally under any binomial or multinomial sampling plans.
description: https://arxiv.org/abs/1801.10547
Lei-travão: da limitação do direito de emenda parlamentar novecentista a uma limitação do poder legislativo, decretada em 2021 (Comentário ao Acórdão do Tribunal Constitucional n.º 545/2021)
Creators: name: Martins, Maria D’Oliveira
Publisher: name: Católica Law Review
Year: 2022

description: Católica Law Review, v. 6 n. 1 (2022): Direito público
Amicus curiae before the international tribunal for the law of the sea: the prospect of an advisory opinion on climate change and the law of the sea
Creators: name: Rocha, Armando
Publisher: name: Católica Law Review
Year: 2022

description: Having in mind the prospect of a request for an advisory opinion before the International Tribunal for the Law of the Sea, this article aims at assessing what role can be performed by amicus curiae (namely, non-governmental organizations, academia, or members of the scientific community) in such proceedings. This article argues that amicus curiae participation is open, although subject to the court’s discretion, and may provide democratic and aristocratic strength to the court’s advisory opinion. Nonetheless, this article also argues that a very broad amici curiae participation is unwelcome, implying that the International Tribunal for the Law of the Sea will need to follow a rule of limited admission.
description: Católica Law Review, v. 6 n. 1 (2022): Direito público
A Reproducible Data Analysis Workflow With R Markdown, Git, Make, and Docker
Creators: name: Peikert, Aaron
name: Brandmaier, Andreas
Publisher: name: Humboldt-Universität zu Berlin
Year: 2021
Subjects: subject: reproducibility
subject: R
subject: version management
subject: dynamic document generation
subject: dependency management
subject: containerization
subject: open science
subject: 004 Informatik

description: In this tutorial, we describe a workflow to ensure long-term reproducibility of R-based data analyses. The workflow leverages established tools and practices from software engineering. It combines the benefits of various open-source software tools including R Markdown, Git, Make, and Docker, whose interplay ensures seamless integration of version management, dynamic report generation conforming to various journal styles, and full cross-platform and long-term computational reproducibility. The workflow ensures meeting the primary goals that 1) the reporting of statistical results is consistent with the actual statistical results (dynamic report generation), 2) the analysis exactly reproduces at a later point in time even if the computing platform or software is changed (computational reproducibility), and 3) changes at any time (during development and post-publication) are tracked, tagged, and documented while earlier versions of both data and code remain accessible. While the research community increasingly recognizes dynamic document generation and version management as tools to ensure reproducibility, we demonstrate with practical examples that these alone are not sufficient to ensure long-term computational reproducibility. Combining containerization, dependence management, version management, and dynamic document generation, the proposed workflow increases scientific productivity by facilitating later reproducibility and reuse of code and data.
The dispositional essence of proactive social preferences: The dark core of personality vis-à-vis 58 traits
Creators: name: Hilbig, Benjamin
name: Thielmann, Isabel
name: Zettler, Ingo
name: moshagen, morten
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences

description: Data, analysis scripts, and supplementary results accompanying the article "The dispositional essence of proactive social preferences: The dark core of personality vis-à-vis 58 traits" The data were collected in the context of the Prosocial Personality Project. For the respective documentation and further details, see https://osf.io/m2abp/.
Isawumi Abiola et al 2020.pdf
Creators: name: Abiola Isawumi
name: Mosi, Lydia
Publisher: name: figshare
Year: 2020
Subjects: subject: 110801 Medical Bacteriology
subject: FOS: Health sciences
subject: 110899 Medical Microbiology not elsewhere classified
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110303 Clinical Microbiology
subject: FOS: Clinical medicine
subject: 111706 Epidemiology

description: In vitro Inhibitory Effects of Commercial Antiseptics and Disinfectants on Foodborne and Environmental Bacterial Strains
O efeito direto do acordo de saída do Reino Unido e do acordo de comércio e cooperação – aplicação a estes acordos da jurisprudência do TJUE relativa aos acordos internacionais da União Europeia
Creators: name: Gomes, Joana Gama
Publisher: name: Católica Law Review
Year: 2022

description: Os acordos celebrados pela UE integram a ordem jurídica da União e vinculam a UE e os Estados-Membros. Consequentemente, o TJUE tem competência para apreciar a compatibilidade dos atos das instituições e dos Estados-Membros com esses acordos, podendo permitir a sua invocação pelos particulares quando estes gozem de efeito direto. Neste sentido, também o Acordo de Saída do Reino Unido e o posterior Acordo de Comércio e Cooperação poderão servir de fundamento ao controlo da legalidade dos atos da UE e dos Estados-Membros. Este artigo pretende, assim, analisar a possibilidade de efeito direto das disposições do Acordo de Saída e do Acordo de Comércio e Cooperação. Quanto ao Acordo de Comércio e Cooperação, analisamos ainda a inclusão de uma série de cláusulas que parecem afastar, ab initio, a possibilidade de efeito direto.
description: Católica Law Review, v. 6 n. 1 (2022): Direito público
Multilevel constitutionalism: dialogs and(on) Human Rights
Creators: name: Fachin, Melina Girardi
Publisher: name: Católica Law Review
Year: 2022

description: The aim is to expose how multilevel constitutionalism is structured on those dialogues and its possibilities, especially on peripherical justice systems, as a tool for mitigating the injustices caused, especially to the most vulnerable groups. Based on a literature review, the article concentrates on the dialogues that support this multilevel movement: it delineates where the dialogues take place (the geography of the new multilevel legal space); how the dialogues flow (the methodology used), as well as the multiple meanings that the dialogues can have; and, at the end, it focusses on the subjects that engage in these dialogues. The purpose of this article is to establish a theoretical framework that accounts for the transformative constitutionalism proposed by the multilevel project, based on dialogues about human rights.
description: Católica Law Review, v. 6 n. 1 (2022): Direito público
Os desafios ambientais frente ao hiperconsumo e o episódio da pandemia de COVID-19
Creators: name: Chediek, Juliana Da Silva Ribeiro Gomes
Publisher: name: Católica Law Review
Year: 2022

description: O presente trabalho busca, em primeiro lugar, problematizar a tensão existente entre o consumismo desenfreado pós-moderno e a premente necessidade de preservação do meio ambiente, abordando os novos paradigmas emergidos a partir do Pacto Ecológico Europeu. Com a pandemia de COVID-19, muito embora as restrições de mobilidade e as medidas de confinamento adotadas por alguns países tenham modificado os hábitos de consumo da população, o hiperconsumo continua a ser uma forte característica da sociedade atual. O trabalho traça um breve panorama sobre a mudança de hábitos de consumo provocada pela pandemia de COVID-19, refletindo acerca dos novos desafios diante da urgência da adoção de medidas de desenvolvimento sustentável.
description: Católica Law Review, v. 6 n. 1 (2022): Direito público
Why Technology for Caregivers Fail: A Qualitative Study of GPS-Based Technology Supporting Alzheimer’s Caregivers
Creators: name: Lee, Jaime
Publisher: name: Maryland Shared Open Access Repository
Year: 2018
Subjects: subject: Usability
subject: User Experience
subject: UX
subject: User Research
subject: Accessibility
subject: CX
subject: Customer Experience
subject: Marketing
subject: FOS: Economics and business
subject: Business
subject: Technology
subject: Culture
subject: Governance
subject: Design
subject: Product Design
subject: Inclusive Design
subject: Life-proof
subject: Plain Language
subject: low literacy
subject: Tracking
subject: GPS
subject: Wandering
subject: Alzheimer
subject: Caregiver
subject: Dementia
subject: AT
subject: Assistive Technology
subject: Homecare
subject: Wearable

description: The purpose of this research is to understand the usability challenges of wearable Global Positioning System (GPS)-based technologies for at home caregivers managing wandering effects for loved ones with Dementia, specifically those with Alzheimer's disease. A total of four devices and 14 U.S. participants were studied using semi-structured, in-person qualitative usability methodology and an open coding system in the style of Grounded Theory. Though the study evaluated issues solely related to usability, the results expanded to a much larger design paradigm to be considered for improved and more directed solutions for future advancements that is symbiotic between a company and its end user. The proposed "life-proofing ecosystem", which contains eight pillars within its framework (user experience, customer experience, accessibility, governance, marketing, business, technology, cultural sensitivity) aims for more balanced product evolutions and progressive innovation. Future studies may provide scalar measurements for assessments beyond the proposed framework and ecosystem. Ultimately, the goal is to provide practical guidelines for designing life-proof solutions in today's highly connected society.
SLCO1B1 variants as predictors of methotrexate-related toxicity in children with juvenile idiopathic arthritis
Creators: name: Roszkiewicz, J
name: Michałek, D
name: Ryk, A
name: Swacha, Z
name: Szmyd, B
name: Smolewska, E
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 60506 Virology

description: Objectives: Methotrexate (MTX) administered at the dose 10–15 mg/m2 is currently recommended as the first line therapy in most juvenile idiopathic arthritis (JIA) subtypes. Gastrointestinal side effects and hepatotoxicity are the most prevalent manifestations of MTX intolerance, frequently leading to discontinuation of otherwise effective treatment. Genetic variability within solute carrier organic anion transporter family member 1B1 (SLCO1B1), encoding a hepatic MTX membrane transporter, has been associated with high-dose MTX efficacy and toxicity in paediatric patients with acute lymphoblastic leukaemia. The aim of our study was to determine the association between single-nucleotide polymorphisms in the SLCO1B1 gene (rs4149056, rs2306283) on the disease activity and presence of side effects of MTX therapy in patients with JIA. Method: The study recruited 100 children with JIA of all subtypes treated with MTX. Demographic and clinical parameters were collected at the baseline of MTX therapy and on a control visit 4–6 months after starting MTX. Genotyping was performed using genomic DNA isolated from peripheral blood samples. Results: In comparison to wild-type allele, SLCO1B1 rs4149056 CT/CC variant was significantly associated with higher odds ratio of MTX gastrointestinal side effects occurrence (OR=4.55, 95%CI 1.37-15.13; p=0.013). SLCO1B1 rs4149056 TT subjects were more likely than CT/CC individuals to develop hepatotoxicity (17.86% vs 4.76%, p = 0.046). Conclusion: SLCO1B1 rs4149056 may serve as a determinant of MTX treatment toxicity in children with JIA.
Social stressors and risk of rheumatoid arthritis and their relationship to known modifiable risk factors: results from the Swedish EIRA study
Creators: name: Hedenstierna, L
name: Opava, CH
name: Askling, J
name: Jiang, X
name: Ernestam, S
name: Alfredsson, L
name: Klareskog, L
name: Saevarsdottir, S
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: To investigate whether low social support or low decision latitude at work correlate with risk of rheumatoid arthritis (RA), and whether and how those factors are associated with known modifiable risk factors for RA. The Swedish population-based EIRA study included, from 1996 to 2015, 3724 incident RA cases and 5935 controls, matched for age, gender, and residential area. Participants filled in detailed questionnaires at diagnosis. Using logistic regression, we investigated whether low social support and low decision latitude at work were associated with RA risk, and whether and how these exposures are associated with known modifiable risk factors for RA. Low decision latitude at work was associated with RA risk in unadjusted analyses [odd ratio (OR) = 1.52, 95% confidence interval (CI) = 1.20–1.94], but this association was weakened after adjustment for known RA risk factors (adjusted OR = 1.24, 95% CI = 0.93–1.63). Low social support was not associated with RA risk (unadjusted OR = 1.05, 95% CI = 0.95–1.15). Cases reporting low decision latitude were more often smokers (OR = 2.05, 95% CI = 1.33–3.16), without university degrees (OR = 8.23, 95% CI = 5.13–13.22), and more often female (OR = 2.52, 95% CI = 1.66–3.81), with a similar pattern among controls. Cases reporting low social support were more often men (OR = 1.60, 95% CI = 1.40–1.83), smokers (OR = 1.46, 95% CI = 1.26–1.70), obese (OR = 1.29, 95% CI = 1.09–1.54), physically inactive (OR = 2.78, 95% CI = 1.98–3.90), and without university degrees (OR = 2.04, 95% CI = 1.77–2.36), with a similar pattern among controls. Low decision latitude coexisted with several known environmental/social risk factors for RA, together defining groups of individuals at increased risk of RA. These risk factors should be viewed in context when testing actions to diminish RA risk in prospective studies.
Detection of human cytomegalovirus in synovial neutrophils obtained from patients with rheumatoid arthritis
Creators: name: Xu, X
name: Estekizadeh, A
name: Davoudi, B
name: Varani, S
name: Malmström, V
name: Rahbar, A
name: Söderberg-Nauclér, C
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Objectives: To examine whether signs of an active human cytomegalovirus (HCMV) infection are present in affected joints of patients with rheumatoid arthritis (RA). Method: Polymorphonuclear leucocytes (PMNLs) were obtained from synovial fluid (SF) of 17 RA patients and were analysed for HCMV-pp65 and HCMV-immediate early (IE) proteins using the antigenemia assay. Peripheral blood (PB) and SF obtained from these 17 patients and from 17 additional RA patients (n = 34) were tested for HCMV-IE and pp150 DNA with Taqman polymerase chain reaction. Plasma samples from the patients were analysed for HCMV-immunoglobulin M (IgM) and immunoglobulin G (IgG) by enzyme-linked immunosorbent assay and compared to 71 healthy gender-matched blood donors. Results: HCMV-pp65 protein was detected in 65% of synovial PMNL samples, but in only 18% of PMNLs from PB. In contrast, HCMV IE protein was not found in any of the analysed PMNL samples. On the DNA level, HCMV-IE and pp150 DNA was detected in SF of 13/32 (41%) and 14/23 (61%) of RA patients, respectively. HCMV-IE and pp150 DNA was also found in 24/33 (73%) and in 16/24 (67%) of PB samples obtained from RA patients, respectively. HCMV IgG seroprevalence was 76% in RA patients as well as in healthy controls, while only one RA patient was positive for specific IgM. Conclusions: HCMV pp65 antigen was found in PMNLs from SF of RA patients, indicating an active infection in the affected joint. Future studies are needed to determine whether HCMV infection can aggravate the inflammatory process in these patients.
Gender and sexuality in the ska scene: how the ska community continues to pick it up
Creators: name: Sangaline, Isabella Marie
Publisher: name: No Publisher Supplied
Year: 2022

description: Ska did not die in the 1990s when United States mainstream culture was oversaturated with it, rather, the scene is alive and well as it continues to push the original messaging of the scene, working to make it more equitable. Ska originated in Jamaica in the 1960s, 2 tone ska became popular in England in the 1980s, and third wave ska and ska revival took the United States by storm in the 1990s. Ska was born out of working-class youth culture in Jamaica, then connected to working-class youth culture in England. It spoke to their daily struggles, resisted mainstream society, and gave space to dance and celebrate. Women and queer people have now found and made space for themselves in this socially conscious and anti-racist genre of music. By continuing the tradition of oral history in recording the history of ska music, experiences of individuals show how they make space for themselves in the scene. During the 1990s and early 2000s, local ska scenes supported the genre, now the intimacy of local scenes can be found on social media. Platforms like Twitter and Facebook allow fans and artists to connect directly, spreading their platforms and messaging directly. The present scene has coined the term “new tone” to describe the latest movement within the scene. This term is a reference back to 2 tone, a genre known for being anti-racist, and the idea of pushing the messaging to also be anti-sexist, anti-homophobic, anti-transphobic, and anti-queerphobic. Ska’s ability to celebrate the diversity present in the scene and discuss social issues makes it a fertile genre for protest music. It requires the listener to engage with the music while skanking to the melodies. The current scene is tapping into this trait within the genre to continue making new, innovative ska music.
Concern about malignancy contributes to the psychosocial toll of dermatomyositis
Creators: name: Helm, MF
name: Bazewicz, CG
name: Butt, M
name: Washington, A
name: Shumaker, K
name: Foulke, GT
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Objective: Dermatomyositis (DM) is associated with increased morbidity and mortality, decreased quality of life, and an increased incidence of psychiatric illness. We performed a pilot study to investigate whether concern about malignancy contributes to the psychosocial toll of DM. Method: Patients with a recent DM diagnosis at our institution between 2013 and 2018 and no history of DM-associated malignancy completed standardized questionnaires and a novel survey generated by our group, and participated in focus groups. Results: Seventeen patients (14 females and three males) completed the surveys. The mean Dermatology Life Quality Index (DLQI) score was 2.75. The mean score on the Patient Health Questionnaire-9 (PHQ-9) was 5.35, with a range of 0–20. Our independent DM-specific questionnaire revealed a mean of 17.41 (range 2–40). Conclusion: Concern about the increased risk of malignancy contributes to the psychosocial toll of DM. Individual impacts are highly variable and patient specific. Clinicians should assess for depression and anxiety in patients with DM, understanding that concern for malignancy adds to the total psychosocial burden in some patients.
personality-detection-using-bagged-svm-over-bert.pdf
Creators: name: Amirmohammad Kazemeini
name: Fatehi, Samin
name: Yash Mehta
name: Sauleh Eetemadi
name: Cambria, Erik
Publisher: name: figshare
Year: 2020
Subjects: Computer Engineering

description: Recently, the automatic prediction of personality traits has received increasing attention and has emerged as a hot topic within the field of affective computing. In this work, we present a novel deep learning-based approach for automated personality detection from text. We leverage state of the art advances in natural language understanding, namely the BERT language model to extract contextualized word embeddings from textual data for automated author personality detection. Our primary goal is to develop a computationally efficient, high-performance personality prediction model which can be easily used by a large number of people without access to huge computation resources. Our extensive experiments with this ideology in mind, led us to develop a novel model which feeds contextualized embeddings along with psycholinguistic features toa Bagged-SVM classifier for personality trait prediction. Our model outperforms the previous state of the art by 1.04% and, at the same time is significantly more computationally efficient to train. We report our results on the famous gold standard Essays dataset for personality detection.
Autoantibodies are major predictors of arthritis development in patients with anti-citrullinated protein antibodies and musculoskeletal pain
Creators: name: Eloff, E
name: Martinsson, K
name: Ziegelasch, M
name: Cedergren, J
name: Reckner, Å
name: Skogh, T
name: Karlsson, L
name: Ärlemalm, A
name: Borggreven, NV
name: Trouw, LA
name: Kastbom, A
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Hematology

description: Objectives: Predictors of arthritis development are highly warranted among patients with anti-citrullinated protein antibodies (ACPAs) and musculoskeletal symptoms to optimize clinical management. We aimed to identify clinical and laboratory predictors of arthritis development, including biochemically assessed alcohol consumption, among ACPA-positive patients with musculoskeletal pain. Method: 82 ACPA-positive individuals with musculoskeletal pain but no clinical arthritis were followed for a median of 72 months (interquartile range 57–81 months). We evaluated the prognostic value of baseline clinical and laboratory factors including smoking, symptom duration, age, gender, shared epitope, rheumatoid factor (RF), anti-carbamylated protein antibodies, ACPA levels, erythrocyte sedimentation rate, C-reactive protein levels, tender joint count, patient-reported general well-being, 28-joint Disease Activity Score, and alcohol consumption as measured by phosphatidyl ethanol (PEth) levels in whole blood. Results: During follow-up, 48% developed at least one arthritis. Multivariable analysis revealed an increased risk of arthritis development with RF positivity [hazard ratio (HR) = 2.3, 95% confidence interval (CI) 1.1–4.8, p = 0.028] and higher ACPA levels (HR = 1.0, 95% CI 1.000–1.001, p = 0.002). High levels of RF (HR = 4.4, 95% CI 1.7–11) entailed the highest HR in this ACPA-positive population. Neither clinical characteristics nor alcohol consumption measured by PEth conferred significant prognostic value. Conclusions: ACPA levels and concurrent presence of RF are independent predictors of arthritis development among ACPA-positive patients with musculoskeletal pain. The results are compatible with a dose–response relationship between RA-related autoantibodies and risk of arthritis development.
Health Metrics and Information Behavior: How Users Estimate and Use Self-Quantifying Activity and Health Information (Supplemental Materials)
Creators: name: Ilhan, Aylin
Publisher: name: Zenodo
Year: 2020

description: This supplemental material (survey) was used for the following research project/publication: Ilhan, A. (2020). Health metrics and information behavior: how users estimate and use self-quantifying activity and health information. Journal of Information Science Theory and Practice, 8(3), 47–63. DOI: https://doi.org/10.1633/JISTaP.2020.8.3.4
title: An exploration of public procurement as an instrument for sustainable development: the case of local government areas in Nigeria.
Creators: name: Negedu, JI
Publisher: name: Liverpool John Moores University
Year: 2022

description: Sustainable public procurement is an integral part of sustainable development that seeks to harmonise and evaluate public expenditures of goods and services through different contracting authorities to fulfil public procurement objectives. While the contribution of the sustainable public procurement sector is receiving increasing attention in developed societies, the role of sustainable public procurement is muted in developing communities. There have been many studies exploring the role of public procurement for sustainable development in the local government areas in the western context. However, there is no empirical study of this nature in developing countries such as Nigeria. Hence, this study aims to explore the various mechanisms through which local government authorities in Nigeria utilise their public procurement functions to foster sustainable development regarding the economic, social, and environmental benefits The study reviewed policy documents and practitioner documents on public procurement and sustainability available through the bureau of public procurement, which is the designated commission for public procurement in Nigeria. Adopting a qualitative approach, thirteen local government areas were utilised to explore the challenges and opportunities for addressing sustainability imperatives through public procurement. Using semi-structured interviews, this study conducted twenty-four interviews of public procurement professionals to gain in-depth knowledge of the extent to which sustainability is incorporated into current public procurement practices and how sustainable public procurement can be used as an instrument for sustainable development. This study confirmed some of the challenges that have been reported in the literature. In addition, the study found contextual factors such as lack of autonomy, nepotism, absence of e-procurement, reluctance to change, and absence of the rule of law that add to the challenges of achieving sustainable public procurement in Nigeria. This study also has practical implications for practitioners through the application of the proposed theoretical framework to achieve sustainability in public procurement. This will also help the local government meets the sustainable development goal 12 (responsible consumption and production) target 7 (which is sustainable public procurement)
title:  Notizie di rinvenimenti di laterizi bollati e altre antichità al Palombaro Maruffi in documenti d’archivio
Creators: name: Calcani  , Giuliana
Publisher: name: Roma TrE-Press
Year: 2016

description: La scoperta di alcuni documenti d’archivio permette di circostanziare meglio la nostra conoscenza sulla storia delle scoperte archeologiche nei terreni di proprietà della famiglia Maruffi, sull’uso privato dei monumenti antichi e sul conflitto tra gli interessi dei proprietari terrieri e la nuova idea di tutela del patrimonio culturale, nel corso del XIX secolo.
description: Tracce del paesaggio antico nel Suburbio. I laterizi bollati nella raccolta Maruffi
title:  Villa Maruffi: la collezione dei bolli laterizi
Creators: name: Alegiani  , Silvia
Publisher: name: Roma TrE-Press
Year: 2016

description: Il catalogo dei laterizi della collezione Maruffi offre un’analisi dettagliata dei materiali che presentano bolli epigrafici o anepigrafi supplementari, conservati all’interno della villa.
Lo studio presenta spunti di riflessione sui probabili luoghi di ritrovamento, sui contesti cui essi appartenevano e sull’origine delle produzioni. Un’attenzione particolare è data alla presenza di bolli non iscritti sul supporto: alcuni di questi possono costituire la base per una nuova riflessione circa la datazione e la finalità dei bolli supplementari anepigrafi, ancora oggi poco chiara.
description: Tracce del paesaggio antico nel Suburbio. I laterizi bollati nella raccolta Maruffi