Additional file 1 of Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals
Creators: name: Richardson, Victorya
name: Engel, Nora
name: Kulathinal, Rob J.
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Distributions of counts per gene for unfiltered and filtered expression data in mouse and human. Figure S2. Cophenetic correlation plots of NMF clusters across factorization rank, or the specified number of clusters inputted into NMF, in male mouseand female mouse. Figure S3. Cophenetic correlation plots of NMF clusters across factorization rank, or the specified number of clusters inputted into NMF, in male humanand female human. Figure S4. Average expression value of each gene from each NMF cluster metagene across samples in male and female mouse. Figure S5. Average expression value of each gene from each NMF cluster metagene across human samples of males and females. Figure S6. Genes with the highest and lowest principal component scores for the top 15 principal components of gene expression data in mouse. Figure S7. Genes with the highest and lowest principal component scores for the top 15 principal components of gene expression data in human. Figure S8. Bar plots of the number of interactions between each groupnormalized by the number of DEGs at each developmental stage. Figure S9. Median number of enriched NMF clusters per biological processGOSlim term, normalized by cluster size, between mouse male and female. Figure S10. Median number of enriched NMF clusters per biological processGOSlim term, normalized by cluster size, between human male and female. Figure S11. Median number of enriched NMF clusters per cellular componentGOSlim term, normalized by cluster size, between mouse male and female. Figure S12. Median number of enriched NMF clusters per cellular componentGOSlim term, normalized by cluster size, between human male and female. Figure S13. Median number of enriched NMF clusters per molecular functionGOSlim term, normalized by cluster size, between mouse male and female. Figure S14. Median number of enriched NMF clusters per molecular functionGOSlim term, normalized by cluster size, between human male and female. Figure S15. Median number of enriched NMF clusters per biological processGOSlim term, normalized by cluster size, between male mouse vs. humanand female mouse vs. human. Top five terms with the largest difference between mouse and human are labeled. Figure S16. Median number of enriched NMF clusters per cellular componentGOSlim term, normalized by cluster size, between male mouse vs. humanand female mouse vs. human. Top five terms with the largest difference between mouse and human are labeled. Figure S17. Median number of enriched NMF clusters per molecular functionGOSlim term, normalized by cluster size, between male mouse vs. humanand female mouse vs. human. Top five terms with the largest difference between mouse and human are labeled. Figure S18. Heatmap of the normalized number of NMF clusters enriched under each GOslim term for biological process. Figure S19. Heatmap of the normalized number of NMF clusters enriched under each GOslim term for cellular component. Figure S20. Heatmap of the normalized number of NMF clusters enriched under each GOslim term for molecular function.