cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Understanding the physical activity, body image, and quality of life experiences for young adult males living with and beyond cancer.
Creators: name: Dhruva, Tana
Publisher: name: Kinesiology
Year: 2024
Subjects: subject: Exercise Oncology
subject: Physical Activity
subject: Body Image
subject: Quality of Life
subject: Young Adult
subject: Oncology

description: Purpose: For young adults (YA), cancer diagnosis and subsequent treatments may result in physical changes that can negatively impact both body image (BI) and health-related quality of life (HRQL). Physical activity (PA) is an evidence-based tool that has been found to impact both BI and HRQL. However, most research to date has focused on the perspectives of older females and males. To address this gap in the literature, we explored the experiences of PA, BI, and HRQL in YA males living with and beyond cancer. Methods: A mixed-methods study was conducted with YA males (biological sex or those who identify as males) diagnosed with cancer between the ages of 20-39. Eligible participants were recruited through pre-existing exercise oncology studies, support organizations, and social media. Self-reported questionnaires assessed PA (modified Godin Leisure-Time Exercise Questionnaire), BI (Body Image Scale), and HRQL (Functional Assessment of Cancer Therapy-General). Descriptive statistics were utilized to summarize the sample characteristics and questionnaire data. Semi-structured interviews, analyzed using interpretive description, facilitated a deeper understanding of the participants’ experiences of PA, BI, and HRQL. Results: Participants (n= 9; mean age= 33.1 ± 3.6) participated in 180 minutes of physical activity/week (range= 0 – 720 minutes) and reported a leisure score index of 19 (range= 15 – 90), which is considered moderately active. Participants demonstrated low to moderate BI dissatisfaction (range= 11 – 17; median=14) and above average HRQL scores (range= 62 – 79; median= 68). Themes developed from interviews (n= 7) included (1) loss of identity due to cancer, (2) building autonomy and identity using PA, and (3) the “should” behind BI. Conclusion: Based on the findings from this study, PA for YA males may support rebuilding one’s identity and BI. Development of exercise oncology resources for young males may consider addressing BI (through education or programming, such as exercise prescription), with the ultimate goal of enhancing HRQL.
Ultrafast spectral diffusion measurement on nitrogen vacancy centers in nanodiamonds using correlation interferometry
Creators: name: Wolters, Janik
name: Sadzak, Nikola
name: Schell, Andreas W.
name: Schröder, Tim
name: Benson, Oliver
Publisher: name: arXiv
Year: 2012
Subjects: subject: Optics (physics.optics)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Spectral diffusion is the phenomenon of random jumps in the emission wavelength of narrow lines. This phenomenon is a major hurdle for applications of solid state quantum emitters like quantum dots, molecules or diamond defect centers in an integrated quantum optical technology. Here, we provide further insight into the underlying processes of spectral diffusion of the zero phonon line of single nitrogen vacancy centers in nanodiamonds by using a novel method based on photon correlation interferometry. The method works although the spectral diffusion rate is several orders of magnitude higher than the photon detection rate and thereby improves the time resolution of previous experiments with nanodiamonds by six orders of magnitude. We study the dependency of the spectral diffusion rate on the excitation power, temperature, and excitation wavelength under off-resonant excitation. Our results suggest a strategy to increase the number of spectrally indistinguishable photons emitted by diamond nanocrystals.
description: 5 pages, 4 figures, 1 supplementary
Ein römischer Kochtopf unter der Dortmunder Brauerei
Creators: name: Eggenstein, Georg
name: Knippschild, Sven
Publisher: name: Archäologie in Westfalen-Lippe
Year: 2023

description: .
description: Archäologie in Westfalen-Lippe, ARCHÄOLOGIE IN WESTFALEN 2021 (2022)
Temperature Distribution and Gradient Effects on Steel-Concrete Composite Girder Bridge
Creators: name: Nayeem, Mostansir Billah
Publisher: name: Schulich School of Engineering
Year: 2024
Subjects: subject: Temperature field
subject: Finite Element Analysis
subject: Concrete strength
subject: Composite bridges
subject: Thermal loads
subject: Climate conditions
subject: Engineering--Civil
subject: Engineering

description: Thermal loads are a crucial environmental component that significantly affects the performance of bridges, especially under extreme climate conditions. Previous research suggests that under extreme climate situations, the impact of temperature may surpass that of dead and live loads, hence emphasizing the need to study the temperature gradient effect. While numerous studies have investigated the effects of temperature variations on concrete or steel bridges, relatively limited exploration has been conducted on the thermal effects experienced by steel-concrete composite bridges. Given substantial disparities in thermal performance between steel and concrete, understanding the temperature field and gradient effect in steel-concrete composite box girder bridges is paramount for both engineers and researchers. However, determining the temperature field within composite bridges requires more sophisticated modeling and analysis. Analytical methods often face challenges in providing accurate temperature field results due to the complex geometry and boundary conditions in real structures. Consequently, numerical simulation has emerged as the most effective approach to estimating the temperature field of bridge structures. The overall objective of this research is to investigate the impact of temperature field and local climatic conditions on the thermal response of steel-concrete composite girder. This study involves developing an efficient Finite Element (FE) model of a dimensionally reduced steel-concrete composite bridge girder to assess the structural effects of a 24-hour simulated temperature field through a sequentially coupled thermo-mechanical analysis technique in Abaqus. The three-dimensional numerical model is validated against existing experimental results conducted in a laboratory environment. Results demonstrate that under similar thermal boundary conditions, composite bridge girder specimens with varying concrete strengths exhibit discernible variations in stress values. Additionally, this study also presents a refined simulation approach utilizing Canadian location-specific historical weather and climate data to analyze the temperature field of a steel-concrete composite girder bridge in Calgary. The utilization of historical meteorological data ensures that the simulated thermal responses closely align with the actual environmental conditions experienced by the bridge. This finite element model can be used as an effective tool for predicting temperature fields by accounting for the unique climatic data of individual bridge locations.
Direct numerical simulation of fragmentation of droplets
Creators: name: Jalaal, Maziyar
Publisher: name: University of British Columbia
Year: 2012

description: The work described in the present thesis is related to a series of projects that I worked on toward the better understanding of fragmentation phenomena. In the past decades, the science of fragmentation has attracted many attentions within the researchers due to its wide range of applications. However, because of the complexity of the subject, even its basic concepts need more investigations. This thesis starts with an introduction to fragmentation of droplets using experimental or numerical approaches. It is discussed that the current mathematical and experimental tools are not able to describe all the details. Thus, high performance numerical simulations are the best alternatives to study the breakup of droplets. The introduction is followed by a discussion on the numerical method and the ranges of the non-dimensional groups. It is described that an adaptive, volume of fluid (VOF) method based on octree meshing is used, providing a notable reduction of computational cost. The rest of the thesis basically discusses the obtained results using direct numerical simulations. Two main geometries are investigated: falling droplets and droplets in a stream. For the case of falling droplets, three simulations with different Eötvös numbers are performed. For the case of droplets in a stream, two-dimensional and three-dimensional simulations are performed for a range of Weber number. The results are compared with the available mathematical theories and it is shown that the analysis presented here precisely demonstrates the mechanism of the bag breakup of falling droplets and instability growth over the droplets in an external high-speed flow. The outcomes can significantly assist the development of the secondary atomization and turbulent two-phase flows modelling.
Additional file 2 of The use of head helmets to deliver noninvasive ventilatory support: a comprehensive review of technical aspects and clinical findings
Creators: name: Coppadoro, Andrea
name: Zago, Elisabetta
name: Pavan, Fabio
name: Foti, Giuseppe
name: Bellani, Giacomo
Publisher: name: figshare
Year: 2021
Subjects: subject: Biophysics
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy

description: Additional file 2. Color image of helmet in a clinical scenario.
DC electrokinetics for spherical particles in salt-free concentrated suspensions including ion size effects
Creators: name: Roa, Rafael
name: Carrique, Félix
name: Ruiz-Reina, Emilio
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We study the electrophoretic mobility of spherical particles and the electrical conductivity in salt-free concentrated suspensions including finite ion size effects. An ideal salt-free suspension is composed of just charged colloidal particles and the added counterions that counterbalance their surface charge. In a very recent paper [Roa et al., Phys. Chem. Chem. Phys., 2011, 13, 3960- 3968] we presented a model for the equilibrium electric double layer for this kind of suspensions considering the size of the counterions, and now we extend this work to analyze the response of the suspension under a static external electric field. The numerical results show the high importance of such corrections for moderate to high particle charges, especially when a region of closest approach of the counterions to the particle surface is considered. The present work sets the basis for further theoretical models with finite ion size corrections, concerning particularly the ac electrokinetics and rheology of such systems.
description: 14 pages, 11 figures
New synaptic organizing proteins and their roles in excitatory and inhibitory synapse development
Creators: name: Pettem, Katherine Laura
Publisher: name: University of British Columbia
Year: 2013

description: The brain consists of billions of neurons. During development, these neurons must migrate to their proper position and form connections with neighboring neurons to form networks. The specificity and maturation of these connections, or synapses, are critical for proper brain function, including learning, memory and cognition. Many cell adhesion molecules (CAMs) are involved in the formation and maturation of synapses, including the well-characterized neuroligin-neurexin pair. In this study, two new synapse modifying proteins, calsyntenin and MDGA, are characterized using in vitro assays and primary hippocampal neuron cultures. Calsyntenin-3 was identified in an un-biased screen to search for new synaptogenic proteins. It is a post-synaptic transmembrane protein that induces the formation of excitatory and inhibitory presynaptic specializations in contacting axons via extracellular cadherin and LNS domains. Overexpression of calsyntenin-3 in neurons increases presynaptic protein clustering. Interestingly, calsyntenin-3 binds to α-neurexins with high affinity, suggesting presynaptic induction is mediated through trans-synaptic signaling with neurexins. MDGAs are a family of synaptic GPI-linked proteins that bind neuroligin-2 with high affinity. MDGA1 blocks the presynaptic induction activity of neuroligin-2, through blocking binding to neurexins, via extracellular immunoglobulin domains. Overexpression of MDGA1 in neurons specifically decreases inhibitory synapses, while knockdown increases inhibitory synapses. Interestingly, like other synaptic proteins including neurexin and neuroligin, MDGAs have recently been linked to autism spectrum disorders and schizophrenia. Thus, the characterization of the synapse-promoting calsyntenin-3 and the synapse-reducing MDGA1 shed new light on the mechanisms by which synaptogenesis is regulated. Investigating the complex interplay between molecular players during synaptogenesis is critical not only for understanding normal brain development, but also for providing insight into neurodevelopmental disorders.
Biobased building blocks from 5hydroxymethylfurfural via 1hydroxyhexane2,5dione as intermediate
Creators: name: Woźniak, Bartosz
Publisher: name: Universität Rostock
Year: 2018
Subjects: subject: 540 Chemistry & allied sciences

description: This dissertation reports on the synthesis and applications of the biomass-derived 1-hydroxyhexane-2,5-dione (HHD). A new catalytic process was developed for the hydrogenation/hydrolytic ring opening of 5-hydroxymethylfurfural (5-HMF) resulting in the formation of HHD in good yields. Furthermore, HHD was converted to useful follow-up products including pyrroles and cyclopentanone derivatives. Additionally, readily accessible rhenium(VII) oxide was used for the catalytic deoxydehydration of renewable triols under solvent-free and aerobic conditions resulting in formation of the hydroxy-alkenes.
Elucidating the role of prolactin receptor during β cell adaptation to metabolic stressors
Creators: name: Lee, Daniel
Publisher: name: Cumming School of Medicine
Year: 2024
Subjects: subject: Incretin effect
subject: Diabetes
subject: Biochemistry

description: The role of prolactin receptor (PRLR) during β cell adaptation to pregnancy has been extensively studied. Human epidemiological studies have revealed a potential role of prolactin outside pregnancy in maintaining glucose homeostasis. In this study, we discovered that the absence of PRLR in pancreatic β cells leads to impaired glucose tolerance in multiparous mice challenged with a high-fat diet (HFD). Unlike during pregnancy, where PRLR regulates β cell mass expansion, we observed that PRLR had a smaller role in regulating β cell mass in this model. Pancreatic islets from our knockout mice had a similar insulin secretory capacity as the wild-type mice in vitro, suggesting that an in vivo factor was responsible for the difference in glucose homeostasis. Interestingly, a difference in in vivo insulin secretion was observed when mice were challenged with oral but not intraperitoneal glucose, suggesting a defect in the incretin effect. The incretin effect, where oral glucose administration elicits a greater insulin secretory response compared to intravenous administration, is mediated by incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). We found a reduction in mRNA expressions of both incretin hormone receptors, GIP receptor (Gipr) and GLP-1 receptor (Glp-1r), in the pancreatic islets of our islet-specific PRLR knockout mice in comparison to wild-type controls after 12 weeks of HFD. Additionally, the mRNA expression of transcription factors, E2F transcription factor 1 (E2f1) and peroxisome proliferator-activated receptor-γ (Pparg), which have been shown to regulate the expressions of Gipr and Glp-1r and are downstream of PRLR, were downregulated. Together, these results suggest PRLR may have a role in the maintaining incretin effect during metabolic stress outside of pregnancy. Our findings contribute to our understanding of the complexity of PRLR in maintaining glucose homeostasis outside of pregnancy.
Coarse-graining renormalization by higher-order singular value decomposition
Creators: name: Xie, Z. Y.
name: Chen, J.
name: Qin, M. P.
name: Zhu, J. W.
name: Yang, L. P.
name: Xiang, T.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a novel coarse graining tensor renormalization group method based on the higher-order singular value decomposition. This method provides an accurate but low computational cost technique for studying both classical and quantum lattice models in two- or three-dimensions. We have demonstrated this method using the Ising model on the square and cubic lattices. By keeping up to 16 bond basis states, we obtain by far the most accurate numerical renormalization group results for the 3D Ising model. We have also applied the method to study the ground state as well as finite temperature properties for the two-dimensional quantum transverse Ising model and obtain the results which are consistent with published data.
description: 11 pages, 16 figures
Additional file 1 of A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa
Creators: name: Qureshi, Alima
name: Connolly, John B.
Publisher: name: figshare
Year: 2021
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Risk of bias analysis. Table S1. A summary of the results of risk of bias assessments undertaken on each individual study. Table S2. Studies with statistically significant changes in absolute densities of vector species. Table S3. Studies without statistically significant changes in absolute densities of vector species. Category ID studies dismissed from qualitative assessment in this review, as providing only weak evidence for competitive release or suggesting alternative explanations for changes in vector species composition.
The Deployment of U.S. Drones in Afghanistan: Deadly Sky and Unmanned Injustice
Creators: name: Benjamin, Prof. (Dr.) M.Suresh
Publisher: name: figshare
Year: 2023
Subjects: International humanitarian and human rights law
International criminal law
Public international law

description: This paper explores the complex relationship between drones, war crimes, and environmental damage in the context of the ongoing conflict in Afghanistan. Drones have become an increasingly common tool in modern warfare, offering unparalleled surveillance and strike capabilities. However, their use has also raised ethical and legal questions, particularly when it comes to the potential for civilian casualties and violations of international humanitarian law. In Afghanistan, the use of drones by the United States and its allies has been linked to a number of alleged war crimes, including the killing of civilians and the destruction of civilian infrastructure. Additionally, the environmental impact of drone strikes has been largely overlooked, despite the fact that they often target remote and ecologically sensitive areas. This abstract considers the potential consequences of these actions for the people of Afghanistan and the wider world, highlighting the need for greater accountability and transparency in the use of drones in conflict.
Ein neuer westfälischer Fibeltyp – mehrteilige Fibeln der jüngeren Eisenzeit und ihre Vorbilder
Creators: name: Zeiler, Manuel
name: Müsch, Eugen
Publisher: name: Archäologie in Westfalen-Lippe
Year: 2023

description: .
description: Archäologie in Westfalen-Lippe, ARCHÄOLOGIE IN WESTFALEN 2021 (2022)
Probing the activity of the inhibitor of growth 1a (ING1a) gene promoter under conditions of cellular stress
Creators: name: Hill, Alexander William
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Biochemistry
subject: Biology--Molecular

description: The INhibitor of Growth (ING) family of proteins was initially characterized in 1996 when subtractive hybridization studies revealed a novel type II tumor suppressor, which the authors called ING1. Since then, additional members of the family have been discovered and characterized as important epigenetic regulators, influencing various cellular processes such as stemness, growth, and development. Previous studies have demonstrated that one of the main isoforms of ING1, named ING1a, shows increased expression in senescent cells, with overexpression of the protein resulting in the premature senescence of young fibroblasts. Classically, senescence is a phenotype that occurs as a result of telomere attrition, causing a DNA damage response that ultimately puts the cell in growth arrest. More recent work has shown that the application of various cellular stressors can induce senescence in cells which have otherwise not reached their replicative lifespan, termed stress-induced premature senescence (SIPS). Currently, the relationship between ING1a and cellular stress is incompletely understood, especially at the level of transcriptional control. In the current work, analysis of predicted transcription factors was performed for the ING1a promoter in addition to other stress and senescence-related promoters, demonstrating great overlap between ING1a and senescence marker p16. qPCR analysis of predicted factors showed decreased expression of FOXD1, FOXL1, and MAZ in senescent fibroblasts. ChIP-qPCR against MAZ was performed, validating the transcription factor prediction and showing that MAZ binds to the ING1a promoter. Comparison between promoter-driven constructs and the endogenous promoters revealed that there is likely considerable epigenetic regulation controlling the expression of ING1a, though transcriptional elements sensitive to oxidative stress are likely present.
Das älteste Gräberfeld im Mittelgebirge Südwestfalens bei Lennestadt-Elspe
Creators: name: Chanko, Joanna
name: Zeiler, Manuel
Publisher: name: Archäologie in Westfalen-Lippe
Year: 2023

description: .
description: Archäologie in Westfalen-Lippe, ARCHÄOLOGIE IN WESTFALEN 2021 (2022)
Robust Kalman tracking and smoothing with propagating and non-propagating outliers
Creators: name: Ruckdeschel, Peter
name: Spangl, Bernhard
name: Pupashenko, Daria
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistics Theory (math.ST)
subject: Applications (stat.AP)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 93E11, 62F35

description: A common situation in filtering where classical Kalman filtering does not perform particularly well is tracking in the presence of propagating outliers. This calls for robustness understood in a distributional sense, i.e.; we enlarge the distribution assumptions made in the ideal model by suitable neighborhoods. Based on optimality results for distributional-robust Kalman filtering from Ruckdeschel[01,10], we propose new robust recursive filters and smoothers designed for this purpose as well as specialized versions for non-propagating outliers. We apply these procedures in the context of a GPS problem arising in the car industry. To better understand these filters, we study their behavior at stylized outlier patterns (for which they are not designed) and compare them to other approaches for the tracking problem. Finally, in a simulation study we discuss efficiency of our procedures in comparison to competitors.
description: 27 pages, 12 figures, 2 tables
Additional file 1 of Improving the quality of malaria diagnosis in southern Africa through the development of a regional malaria slide bank
Creators: name: Moodley, Bhavani
name: Chinorumba, Anderson
name: Hamman, Cheryl
name: Matamba, Avhatakali
name: Sikaala, Chadwick H.
name: Kleinschmidt, Immo
name: Frean, John
Publisher: name: figshare
Year: 2021
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Overview of training programme for new MSB staff.
A Modder’s Guidelines for Moddable Game Development
Creators: name: Crémer, Loïc
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Mod
subject: Modding
subject: Guidelines
subject: Game Design
subject: Video Games
subject: Game Studies
subject: ROM Hack
subject: Pokémon
subject: Hand of Fate
subject: The Elder Scrolls
subject: Skyrim
subject: Tool Design
subject: Documentation
subject: Community Support
subject: Benefits of Modding
subject: Accessibility
subject: Inclusion
subject: Autobiographical Design
subject: First-Person Research
subject: Moddable Game Design
subject: Idealized Tool
subject: Proof-of-Concept
subject: Mod Distribution
subject: Modder Compensation
subject: User Generated Content
subject: Open Game License (OGL)
subject: Computer Science

description: The act of unofficially modifying a video game known as modding may convey a range of benefits to its host game, including an expanded sales lifetime and a vision of what a game may have looked like had developers made different choices, among others. In this thesis, I make a case for this beneficial nature of modding and develop a set of guidelines for developing moddable games with the aim of shifting industry perspectives towards the practice, which tend to be mixed, toward a more positive outlook and help mod-encouraging studios provide a better modding experience to their users. This set is built on four pillars, each representing a stage in the development of a moddable game: Designing a moddable game, creating robust tools, writing effective documentation, and supporting the community. I created these guidelines using data collected from an autobiographical design study, wherein I became a modder myself and built modifications for three video games: Nintendo’s Pokémon FireRed Version, Bethesda’s The Elder Scrolls V: Skyrim, and Defiant Development’s Hand of Fate 2. After writing the set, I then created a proof-of-concept tool in line with two of its principles to demonstrate what an idealized modding tool based on my research might look like. These guidelines outline what makes a game more moddable, what makes a good modding tool, and how best to support a moddable game after launch. It is my intention that this thesis demystifies the process of creating moddable games and that the lessons learned in this project can prove useful to modders, researchers, and professional developers alike.
Erwitte-Völlinghausen – verlorene Form statt verlorener Fundplatz
Creators: name: Sicherl, Bernhard
name: Hussein-Oglü, Rashida
Publisher: name: Archäologie in Westfalen-Lippe
Year: 2023

description: .
description: Archäologie in Westfalen-Lippe, ARCHÄOLOGIE IN WESTFALEN 2021 (2022)
Suzaku and XMM-Newton Observations of the Fornax cluster: Temperature and Metallicity Distribution
Creators: name: Murakami, Hideyoshi
name: Komiyama, Madoka
name: Matsushita, Kyoko
name: Nagino, Ryo
name: Sato, Takuya
name: Sato, Kosuke
name: Kawaharada, Madoka
name: Nakazawa, Kazuhiro
name: Ohashi, Takaya
name: Takei, Yoh
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Suzaku observed a central region and five offset regions within 0.2 r180 in the Fornax cluster, a nearby poor cluster, and XMM-Newton mapped the cluster with 15 pointings out to 0.3 r180. The distributions of O, Mg, Si, S, and Fe in the intracluster medium (ICM) were studied with Suzaku, and those of Fe and temperature were studied with XMM. The temperature of the ICM gradually decreases with radius from 1.3 keV at 0.04 r180 to 1 keV at 0.2-0.3 r180. If the new solar abundances of Lodders et al. (2003) and a single-temperature plasma model are adopted, O, Mg, Si, S, and Fe show similar abundances: 0.4-0.6 solar within 0.02-0.2 r180. This Fe abundance is similar to those at 0.1-0.2 r180 in rich clusters and other groups of galaxies. At 0.2-0.3 r180, the Fe abundance becomes 0.2-0.3 solar. A two-temperature plasma model yields ICM abundances that are higher by a factor of 1.2-1.5, but gives similar abundance ratios among O, Mg, Si, S, and Fe. The northern region has a lower ICM temperature and higher brightness and Fe abundance, whereas the southern region has a higher ICM temperature and lower brightness and Fe abundance. These results indicate that the cD galaxy may have traveled from the north because of recent dynamical evolution. The cumulative oxygen- and iron-mass-to-light ratios within 0.3 r180 are more than an order of magnitude lower than those of rich clusters and some relaxed groups of galaxies. Past dynamical evolution might have hindered the strong concentration of hot gas in the Fornax cluster's central region. Scatter in the IMLR and similarity in the element abundances in the ICM of groups and clusters of galaxies indicate early metal synthesis.
description: 15 pages, 13 figures, accepted for publication in PASJ
Vom Neolithikum bis zur Eisenzeit – Gräber und Siedlungsspuren in Legden-Asbeck
Creators: name: Schacht, Christian Peter
Publisher: name: Archäologie in Westfalen-Lippe
Year: 2023

description: .
description: Archäologie in Westfalen-Lippe, ARCHÄOLOGIE IN WESTFALEN 2021 (2022)
title: Lesbarkeit Deutscher Kinderbücher: Eine kommentierte Übersicht deutscher Literatur
title: Readability of German Children’s Books: An Annotated Bibliography of German Literature
titleType: AlternativeTitle
Creators: name: Dressler, Roswita
name: Siggelkow, Miriam
Publisher: name: Werklund School of Education
Year: 2024
Subjects: Lesbarkeit
Kinderbücher
Readability
deutsche Literatur
German literature
Children's books
Erst- und Zweitsprache
Literaturliste
bibliography
first or second language
Textkomplexität

description: Diese kommentierte Übersicht Deutscher Literatur zum Thema „Lesbarkeit“ bietet Wissenschaftler*innen, die kein Deutsch lesen, reichhaltigen Zugang zu relevanter Literatur. Da Kinder auf der ganzen Welt in Deutsch als Erst- und Zweitsprache das Lesen erlernen, ist das Wissen über das Verständnis und die Konzeptionierung von Lesbarkeit in der deutschsprachigen Welt bedeutsam. This annotated bibliography of German literature on the topic of readability provides access to a wealth of literature to researchers who do not read German. With children around the world learning to read in German as a first or second language, a knowledge of how readability is understood and conceptualized in the German-speaking world is valuable.
description: Die von uns gesichtete Literatur stützt die allgemeine Auffassung, dass Lesbarkeit aus drei Komponenten besteht: literarische und kontextuelle Aspekte sowie Aspekte, die die Textkomplexität betreffen. Zu den literarischen Aspekten gehören das Setting, die Komplexität der Charaktere und die Handlungsstruktur. Kontextbezogene Aspekte beziehen sich auf den sozialen Kontext, in dem Schüler unterrichtet werden, sei es im Kontext der Erstoder Zweitsprache, einer Minderheitensprache oder einer dominanten Hochsprache usw. Die Textkomplexität umfasst Wortschatz (Lexik) und Grammatik (Morphologie und Syntax). Oftmals betrachten Forscher die Lesbarkeit nur aus einer dieser Perspektiven. Aber um ein vollständiges Bild zu erhalten, muss der Querschnitt aller drei Aspekte betrachtet werden. The literature we reviewed supports the conceptualization that readability is made up of three components: literary, contextual, and text complexity aspects. Literary aspects include setting, character complexity, and event structure. Contextual aspects refer to the social context in which students are instructed, be it first or second language contexts, minority or dominant societal language, etc. Text complexity involves vocabulary (lexis) and grammar (morphology and syntax). Often researchers approach readability from one of those perspectives, but to gain a complete picture, the cross section of all three needs to be considered.
Additional file 2 of Improving the quality of malaria diagnosis in southern Africa through the development of a regional malaria slide bank
Creators: name: Moodley, Bhavani
name: Chinorumba, Anderson
name: Hamman, Cheryl
name: Matamba, Avhatakali
name: Sikaala, Chadwick H.
name: Kleinschmidt, Immo
name: Frean, John
Publisher: name: figshare
Year: 2021
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. List of laboratories used for MSB sample collection.
Neutrophil localization during C. rodentium-induced colitis
Creators: name: Yoon, Grace Haewon
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Attaching and effacing bacteria
subject: Citrobacter rodentium
subject: Neutrophils
subject: Infectious colitis
subject: Colon
subject: Microbiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Intestinal infections by enteropathogenic bacteria like Escherichia coli pose a significant risk to human health worldwide and can contribute to a wide spectrum of different symptoms and diseases. The infection can result in weight loss, diarrhea, hemorrhagic colitis, dehydration and potentially death. To study enteropathogenic colonization further, a murine Citrobacter rodentium (C. rodentium) model is used in this project to understand the activity of neutrophils, often the first cell line of defense, during infection. While it is known that neutrophils are involved in the eradication of C. rodentium, their presence during different phases of C. rodentium infection and functions at these time points, such as inflammation regulation and clearance, remain unknown, especially in the context of recruitment, location, and time. During an infection within the intestine, pathogens encounter many different obstacles such as the mucus layer, intestinal epithelial cells, and innate immune cells. Neutrophils are innate immune cells that are well recognized as first responders during infections, and they are armed with granules that contain toxic agents such as reactive oxygen species, proteases, and antimicrobial peptides/proteins. In the context of C. rodentium infection, it has been shown that neutrophils preferentially phagocytose the bacteria within the cecal lumen during the steady phase of infection; however, the localization and distribution of neutrophils throughout the progression of the infection remains elusive. Previous studies have alluded to the potential of localization in determining function of neutrophils where neutrophils that have undergone transepithelial migration have more bactericidal capabilities. As such, exploring the localization and distribution throughout the different phases of C. rodentium can shed light on the roles that neutrophils play during the infection. Our findings show that neutrophils are abundantly recruited within the colonic mucosa during the acute inflammation phase (7 dpi) and reach the colonic lumen. Cathelicidin, an antimicrobial peptide, deficiency leads to more neutrophil recruitment than its wildtype counterpart upon infection. Furthermore, the bulk RNA sequencing results show that NET formation and degranulation are upregulated neutrophil functions during C. rodentium infection in both cathelicidin-deficient and wildtype mice. By further understanding the behaviour and activity of neutrophils during infection, it can allow us to harness the microbicidal ability of these cells to use as a potential therapeutic in years to come.
Additional file 3 of Improving the quality of malaria diagnosis in southern Africa through the development of a regional malaria slide bank
Creators: name: Moodley, Bhavani
name: Chinorumba, Anderson
name: Hamman, Cheryl
name: Matamba, Avhatakali
name: Sikaala, Chadwick H.
name: Kleinschmidt, Immo
name: Frean, John
Publisher: name: figshare
Year: 2021
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 3. Detailed procedure for mass slide production.
The third moment of quadratic Dirichlet L-functions
Creators: name: Young, Matthew P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We study the third moment of quadratic Dirichlet L-functions, obtaining an error term of size $O(X^{3/4 + \varepsilon})$.
description: 27 pages. v2: modified a remark on p.1
Autonomous Exploration and Mapping of Unknown Environments
Creators: name: Sarfi, Mohammad Hossein
Publisher: name: Schulich School of Engineering
Year: 2024
Subjects: subject: Autonomous exploration
subject: Mapless navigation
subject: Deep Reinforcement Learning in robotics
subject: Risk-sensitive decision making
subject: Multi-robot coordination
subject: Engineering--Mechanical

description: This thesis presents a comprehensive exploration of autonomous exploration and mapping in unknown environments, emphasizing the importance of minimizing exploration time while ensuring high-quality mapping results. It introduces a classical coordinated autonomous exploration strategy inspired by Market-Based task allocation and Ant Colony Optimization techniques. Compared to simpler Market-Based methods, this approach improves efficiency by reducing overlap between robots. The study utilizes a 2D simulation environment to collect training data efficiently, facilitating the evaluation of the proposed methods’ efficiency, adaptability, and generalizability through various experiments. Furthermore, the thesis develops intelligent single-robot autonomous techniques using advanced Deep Reinforcement Learning (DRL) algorithms. Notably, it adopts risk-sensitive strategies, in contrast to traditional risk-neutral approaches in DRL, aiming to enhance exploration efficiency, defined as the time required to complete 95% of the map. The best intelligent policy achieved a significant improvement in exploration efficiency compared to the utility-based classical method. Despite selecting the appropriate DRL algorithm and fine-tuning it accordingly, a comprehensive study and series of experiments are designed to investigate the effects of various state, action, and reward spaces. Moreover, different external features, such as incorporating the Intrinsic Curiosity Module (ICM) or integrating Long-Short Term Memory (LSTM) layers, are considered to further enhance autonomous exploration efficiency. The results demonstrate a significant improvement in autonomous exploration efficiency compared to well-known classical single-robot exploration policies, validating the effectiveness of the suggested novel autonomous exploration strategies. The codes developed for this thesis are available in the Intelligent Dynamics and Control Lab GitHub repository: https://github.com/IDCL-UCalgary
Discrete Dirac system: rectangular Weyl functions, direct and inverse problems
Creators: name: Fritzsche, B.
name: Kirstein, B.
name: Roitberg, I.
name: Sakhnovich, A. L.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Spectral Theory (math.SP)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 34B20, 34L40, 39A12, 47A57

description: A transfer matrix function representation of the fundamental solution of the general-type discrete Dirac system, corresponding to rectangular Schur coefficients and Weyl functions, is obtained. Connections with Szegö recurrence, Schur coefficients and structured matrices are treated. Borg-Marchenko-type uniqueness theorem is derived. Inverse problems on the interval and semiaxis are solved.
description: Section 2 is improved in the second version: some new results on Halmos extension are added and arguments are simplified
Structurally diverse lignans from Solanum lyratum: chemical evidence for their acetylcholinease inhibitory activity
Creators: name: Zhang, Xin
name: Bai, Ming
name: Chang, Ye
name: Huang, Xiao-Xiao
name: Song, Shao-Jiang
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Hematology

description: A chemical investigation of Solanum lyratum Thumb. (Solanace) afforded two new lignans (1b and 3) and eleven known lignan analogues (1a, 2a/2b and 4–11). Compounds 1a/1b and 2a/2b were separated as two pairs of enantiomers by chiral high-performance liquid chromatography (HPLC). Their structures were elucidated by detailed spectroscopic and comparative literature data analysis. The absolute configurations of compounds 1a/1b and 2a/2b were determined by comparing the experimental ECD data with the calculated values. All compounds were evaluated for their acetylcholinesterase (AChE) inhibitory activity. Notably, compared to the positive control, compounds 4 and 9 showed obvious AChE inhibition with their IC50 values of 1.30 ± 0.25 and 0.89 ± 0.04 μM, respectively. In addition, the possible interaction between acetylcholinesterase and the active compounds was also investigated by molecular docking.
Regulation of Fatty Acid Biosynthesis by Protein Phosphorylation of the α-CT Subunit of ACCase in Arabidopsis thaliana
Creators: name: Wong, Lana
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Post-translational modification
subject: Protein phosphorylation
subject: Lipid Metabolism
subject: SLP1
subject: Education--Sciences

description: Reversible protein phosphorylation, the most common post-translational modification, is essential in mediating most cellular functions in living organisms. With recent advances in omics-based technologies and its applications to studying the phosphoproteome of particular organisms, many previously uncharacterized phosphoproteins, protein kinases and protein phosphatases have been identified. Shewanella-like protein phophatase 1 (SLP1), a novel Arabidopsis thaliana protein phosphatase localized to the chloroplast, is a protein of interest as it is predicted to play an antagonistic role to the constitutively active chloroplast localized kinase, casein kinase 2α4 (CK2α4). Through a quantitative mass spectrometry based phosphoproteomics study carried out by previous members of the Moorhead Lab, many putative substrates of AtSLP1 were identified, one of them being the alpha-carboxyltransferase (α-CT) subunit of heteromeric acetyl-CoA carboxylase (htACCase). HtACCase catalyzes the first committed step of de novo fatty acid biosynthesis, and like AtSLP1, is chloroplast localized. HtACCase has been known to interact with the chloroplast envelope membrane through association with an integral membrane protein, however, the identity of this protein has been a mystery until recently. Carboxyltransferase interactors (CTIs), a group of small plastidal proteins of the inner chloroplast envelope have been identified to interact with the α-CT subunit of htACCase in a light-dependent manner. The focus of the research presented here was to characterize α-CT as a substrate of both CK2α4 and SLP1 and to determine the role of protein phosphorylation in lipid metabolism. Here, initial steps were taken in employing phosphospecific antibodies against the S741 site on α-CT, with immunoblot analysis confirming previous findings from a phosphoproteomics study indicating hyperphosphorylation of α-CT in the absence of SLP1. To explore the relationship between protein phosphorylation and the membrane partitioning of ACCase with CTI, recombinant proteins were cloned for subsequent protein-protein interaction studies. By studying the effects of this post-translational modification, we will gain a better understanding of the role of protein phosphorylation in regulating fatty acid biosynthesis, which will ultimately uncover new ways to increase bio-oil production in crops.
"The Quiet Battles of the Home Front War": Civil War Bread Riots and the Development of a Confederate Welfare System
Creators: name: Barber, Edna Susan
Publisher: name: Digital Repository at the University of Maryland
Year: 1986

description: During the American Civil War, more than a dozen food riots erupted in a number of Southern cities. Planned and executed largely by women, these riots were precipitated by extreme food shortages and high market prices, both the result of impressment activity and widespread speculation in foodstuffs. Although several scholars have examined the largest riot which occurred in Richmond, Virginia, in 1863, none have studied them collectively to determine the impact all of these riots exerted on the Confederate war effort or on the roles of Southern women in wartime. Nor has any attempt been made to place these riots in the context of American and European patterns of rioting. In response to riots or as attempts to prevent riots from occurring, a number of state and local governments moved to establish welfare programs to aid the women left destitute by the war. In cities, this took the form of free markets which distributed commodities donated by local farmers. In areas where the population was more dispersed, county or state relief agencies performed a similar function. Women who received supplies had to meet specific requirements to qualify for aid, and, at least in Richmond, the female rioters were excluded from the welfare program because their behavior violated traditional behavioral norms. As the war neared its conclusion, however, this type of riotous activity by Southern women ceased, and the women returned to their more traditional roles in nineteenth-century Southern society. When examined as a group, these riots tend to conform to traditional European food riot patterns such as those described by E.P. Thompson and Louise Tilly, thus giving the women's activities a broader and deeper historical context than they otherwise would have had.
Oberflächenfunde der LBK-Doppelsiedlung von Borgentreich-Großeneder
Creators: name: Pollmann, Hans-Otto
Publisher: name: Archäologie in Westfalen-Lippe
Year: 2023

description: .
description: Archäologie in Westfalen-Lippe, ARCHÄOLOGIE IN WESTFALEN 2021 (2022)