cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mojiangia oreophila (Crepidinae, Cichorieae, Asteraceae), a new species and genus from Mojiang County, SW Yunnan, China, and putative successor of the maternal Faberia ancestor
Creators: name: Yin, Zhi-Jian
name: Wang, Ze-Huan
name: Kilian, Norbert
name: Liu, Ying
name: Peng, Hua
name: Zhao, Ming-Xu
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Asteraceae
subject: Crepidinae
subject: Phylogeny
subject: Taxonomy
subject: Reticulate evolution
subject: Cytonuclear discordance
subject: 500 Naturwissenschaften und Mathematik::580 Pflanzen (Botanik)::580 Pflanzen (Botanik)

description: A single small population of chasmophytic plants is described as Mojiangia oreophila, a monotypic genus in the subtribe Crepidinae, characterised by a unique combination of morphological features, in particular densely long-papillose homomorphic achenes with five main ribs each accompanied by two secondary ribs, coarse brownish pappus bristles, moderately many-flowered capitula, a small involucre with numerous outer phyllaries, perennial rosette herb growth and brown-woolly caudex and leaf axils. Molecular phylogenetic analysis detected that in the nrITS phylogeny M. oreophila forms a clade of its own in the Crepidinae; in the plastid DNA phylogeny it is nested in the clade formed by the hybridogenous genus Faberia, the maternal ancestor of which comes from the Crepidinae and the paternal ancestor from the Lactucinae, where Faberia is placed in nrITS phylogenies. M. oreophila shares several morphological features with Faberia and also shares the expected chromosome number of 2n = 16 with its hitherto unknown maternal ancestor. M. oreophila may therefore be a successor of the maternal ancestor of Faberia. Alternatively, cytonuclear discordance is to be assumed in Mojiangia, caused by chloroplast capture as a result of hybridisation and introgression with Faberia.
Near-Realtime Quantitative Precipitation Estimation and Prediction (RealPEP)
Creators: name: Trömel, Silke
name: Chwala, Christian
name: Furusho-Percot, Carina
name: Henken, Cintia Carbajal
name: Polz, Julius
name: Potthast, Roland
name: Reinoso-Rondinel, Ricardo
name: Simmer, Clemens
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Rainfall
subject: Radars/Radar observations
subject: Satellite observations
subject: Nowcasting
subject: Numerical weather prediction/forecasting
subject: Neural networks
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::551 Geologie, Hydrologie, Meteorologie

description: Precipitation and Flash-Flood Predictions From Minutes to Days What: 250 participants discussed ideas and recent developments in the fields of quantitative precipitation estimation (QPE) based on the exploitation of measurements of polarimetric radars and microwave backhaul links, observation-based quantitative precipitation nowcasting (QPN), numerical quantitative precipitation forecasting (QPF), flash-flood prediction (FFP), and their organization into seamless prediction systems. When: 5–7 October 2020 Where: Online (https://indico.scc.kit.edu/e/realpep_conf)
Secondary collisions and injury severity: A joint analysis using structural equation models
Creators: name: Xie, Kun
name: Ozbay, Kaan
name: Yang, Hong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Objective: This study aims to investigate the contributing factors to secondary collisions and the effects of secondary collisions on injury severity levels. Manhattan, which is the most densely populated urban area of New York City, is used as a case study. In Manhattan, about 7.5% of crash events become involved with secondary collisions and as high as 9.3% of those secondary collisions lead to incapacitating and fatal injuries. Methods: Structural equation models (SEMs) are proposed to jointly model the presence of secondary collisions and injury severity levels and adjust for the endogeneity effects. The structural relationship among secondary collisions, injury severity, and contributing factors such as speeding, alcohol, fatigue, brake defects, limited view, and rain are fully explored using SEMs. In addition, to assess the temporal effects, we use time as a moderator in the proposed SEM framework. Results: Due to its better performance compared with other models, the SEM with no constraint is used to investigate the contributing factors to secondary collisions. Thirteen explanatory variables are found to contribute to the presence of secondary collisions, including alcohol, drugs, inattention, inexperience, sleep, control disregarded, speeding, fatigue, defective brakes, pedestrian involved, defective pavement, limited view, and rain. Regarding the temporal effects, results indicate that it is more likely to sustain secondary collisions and severe injuries at night. Conclusions: This study fully investigates the contributing factors to secondary collisions and estimates the safety effects of secondary collisions after adjusting for the endogeneity effects and shows the advantage of using SEMs in exploring the structural relationship between risk factors and safety indicators. Understanding the causes and impacts of secondary collisions can help transportation agencies and automobile manufacturers develop effective injury prevention countermeasures.
Results of the Wilcoxon signed-rank test from What a difference a day makes—female behaviour is less predictable near ovulation
Creators: name: Kästner, Niklas
name: S. Helene Richter
name: Gamer, Matthias
name: Kaiser, Sylvia
name: Sachser, Norbert
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Behavioural performance of mice - group comparison between the tests rounds
title: Ode to a car
Creators: name: Langage, Langues Et Cultures D'Afrique
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: anthropological_linguistics
subject: poem
subject: Beja
subject: bej
subject: Annotation

description: Recording session done by the collector/researcher in Sinkat, in a field. Were present: the collector/researcher, the speaker and Ahmed Abdallah.
description: Poem about a car
description: Conforms to: Leipzig Glossing Rules
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Variance of Relative Surprisal as Single-Shot Quantifier
Creators: name: Boes, Paul
name: Ng, Nelly H. Y.
name: Wilming, Henrik
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Quantum information processing
subject: Quantum thermodynamics
subject: Resource theories
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: The variance of (relative) surprisal, also known as varentropy, so far mostly plays a role in information theory as quantifying the leading-order corrections to asymptotic independent and identically distributed (IID) limits. Here, we comprehensively study the use of it to derive single-shot results in (quantum) information theory. We show that it gives genuine sufficient and necessary conditions for approximate state transitions between pairs of quantum states in the single-shot setting, without the need for further optimization. We also clarify its relation to smoothed min and max entropies, and construct a monotone for resource theories using only the standard (relative) entropy and variance of (relative) surprisal. This immediately gives rise to enhanced lower bounds for entropy production in random processes. We establish certain properties of the variance of relative surprisal, which will be useful for further investigations, such as uniform continuity and upper bounds on the violation of subadditivity. Motivated by our results, we further derive a simple and physically appealing axiomatic single-shot characterization of (relative) entropy, which we believe to be of independent interest. We illustrate our results with several applications, ranging from interconvertibility of ergodic states, over Landauer erasure to a bound on the necessary dimension of the catalyst for catalytic state transitions and Boltzmann’s H theorem.
Method details from Not equal in the face of habitat change: closely related fishes differ in their ability to use predation-related information in degraded coral
Creators: name: Ferrari, Maud C. O.
name: McCormick, Mark I.
name: Allan, Bridie J. M.
name: Chivers, Douglas P.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: Coral reefs are biodiversity hotpots that are under significant threat due to the degradation and death of hard corals. When obligate coral-dwelling species die, the remaining species must either move or adjust to the altered conditions. Our goal was to investigate the effect of coral degradation on the ability of coral reef fishes to assess their risk of predation using alarm cues from injured conspecifics. Here, we tested the ability of six closely related species of juvenile damselfish (Pomacentridae) to respond to risk cues in both live coral or dead-degraded coral environments. Of those six species, two are exclusively associated with live coral habitats, two are found mostly on dead-degraded coral rubble, while the last two are found in both habitat types. We found that the two live coral associates failed to respond appropriately to the cues in water from degraded habitats. In contrast, the cue response of the two rubble associates was unaffected in the same degraded habitat. Interestingly, we observed a mixed response from the species found in both habitat types, with one species displaying an appropriate cue response while the other did not. Our second experiment suggested that the lack of responses stemmed from deactivation of the alarm cues, rather than the inability of the species to smell. Habitat preference (live coral versus dead coral associates) and phylogeny are good candidates for future work aimed at predicting which species are affected by coral degradation. Our results point towards a surprising level of variation in the ability of congeneric species to fare in altered habitats and hence underscores the difficulty of predicting community change in degraded habitats.
Multivalent non-covalent interactions lead to strongest polymer adhesion
Creators: name: Lallemang, Max
name: Yu, Leixiao
name: Cai, Wanhao
name: Rischka, Klaus
name: Hartwig, Andreas
name: Haag, Rainer
name: Hugel, Thorsten
name: Balzer, Bizan N.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: multivalent interactions
subject: polymer coatings
subject: polymer adhesion
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: Multivalent interactions play a leading role in biological processes such as the inhibition of inflammation or virus internalization. The multivalent interactions show enhanced strength and better selectivity compared to monovalent interactions, but they are much less understood due to their complexity. Here, we detect molecular interactions in the range of a few piconewtons to several nanonewtons and correlate them with the formation and subsequent breaking of one or several bonds and assign these bonds. This becomes possible by performing atomic force microcopy (AFM)-based single molecule force spectroscopy of a multifunctional polymer covalently attached to an AFM cantilever tip on a substrate bound polymer layer of the multifunctional polymer. Varying the pH value and the crosslinking state of the polymer layer, we find that bonds of intermediate strength (non-covalent), like coordination bonds, give the highest multivalent bond strength, even outperforming strong (covalent) bonds. At the same time, covalent bonds enhance the polymer layer density, increasing in particular the number of non-covalent bonds. In summary, we can show that the key for the design of stable and durable polymer coatings is to provide a variety of multivalent interactions and to keep the number of non-covalent interactions at a high level
The Cl--channel TMEM16A is involved in the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks in mice
Creators: name: Maul, Alena
name: Huebner, Antje Kathrin
name: Strenzke, Nicola
name: Moser, Tobias
name: Rübsamen, Rudolf
name: Jovanovic, Saša
name: Hübner, Christian A.
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: TMEM16A
subject: ANO1
subject: cochlea
subject: Kolliker's organ
subject: auditory system
subject: refinement
subject: Mouse
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Before hearing onset (postnatal day 12 in mice), inner hair cells (IHCs) spontaneously fire action potentials, thereby driving pre-sensory activity in the ascending auditory pathway. The rate of IHC action potential bursts is modulated by inner supporting cells (ISCs) of Kölliker’s organ through the activity of the Ca2+-activated Cl--channel TMEM16A (ANO1). Here, we show that conditional deletion of Ano1 (Tmem16a) in mice disrupts Ca2+ waves within Kölliker’s organ, reduces the burst-firing activity and the frequency selectivity of auditory brainstem neurons in the medial nucleus of the trapezoid body (MNTB), and also impairs the functional refinement of MNTB projections to the lateral superior olive. These results reveal the importance of the activity of Kölliker’s organ for the refinement of central auditory connectivity. In addition, our study suggests the involvement of TMEM16A in the propagation of Ca2+ waves, which may also apply to other tissues expressing TMEM16A.
A comprehensive forecast for cosmological parameter estimation using joint observations of gravitational waves and short $γ$-ray bursts
Creators: name: Han, Tao
name: Jin, Shang-Jie
name: Zhang, Jing-Fei
name: Zhang, Xin
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the third-generation (3G) gravitational-wave (GW) detector era, the multi-messenger GW observation for binary neutron star (BNS) merger events can exert great impacts on exploring the cosmic expansion history. In this work, we comprehensively explore the potential of 3G GW standard siren observations in cosmological parameter estimations by considering the 3G GW detectors and the future short $γ$-ray burst (GRB) detector THESEUS-like telescope joint observations. Based on the 10-year observation of different detection strategies, we predict that the numbers of detectable GW-GRB events are 334--674 with the redshifts $z<3.5$ and the inclination angles $ι<15^{\circ}$. For the cosmological analysis, we consider the $Λ$CDM, $w$CDM, $w_0w_a$CDM models, and interacting dark energy (IDE) models. We find that GW can tightly constrain the Hubble constant with precisions of $0.345\%-0.065\%$, but perform not well in constraining other cosmological parameters. Fortunately, GW could effectively break the cosmological parameter degeneracies generated by the mainstream EM observations, CMB+BAO+SN (CBS). When combining the mock GW data with the CBS data, CBS+GW can tightly constrain the equation of state of dark energy $w$ with a precision of 1.26\%, close to the standard of precision cosmology. Meanwhile, the addition of GW to CBS could improve constraints on cosmological parameters by $34.2\%-94.9\%$. In conclusion, GW standard siren observations from 3G GW detectors could play a crucial role in helping solve the Hubble tension and probe the fundamental nature of dark energy.
description: 23 pages, 19 figures; accepted for publication in EPJC
Gender-related morphometric differences in mature and nestling Crowned Eagles, with comments on ringing of eagle nestlings in KwaZulu-Natal, South Africa
Creators: name: McPherson, Shane C
name: Brown, Mark
name: Downs, Colleen T
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Science Policy

description: Although most raptor species are sexually dimorphic, many species are non-discrete in some metrics. A limited amount of existing data for southern Africa suggests that Crowned Eagles Stephanoaetus coronatus exhibit non-discrete sexual dimorphism. Consequently, we investigated gender-related morphometric data of Crowned Eagles with corresponding genetic avian sex tests. Immature (n = 13) and adult (n = 5) Crowned Eagles were trapped, measured and released in KwaZulu-Natal, South Africa from 2012 to 2015. Our results show that tarsus width, body mass, and DI claw (hallux) measurements are suitable for discriminating between sexes of mature Crowned Eagles. We comment on the use of South African Ringing Scheme (SAFRING) and colour read-rings as a marking technique in Crowned Eagles. Furthermore, we suggest suitable parameters for accessing nests and marking nestlings. To aid in the age estimates of nestling eagles, a reference of growth of known-age nestlings is provided.
Preproteins couple the intrinsic dynamics of SecA to its ATPase cycle to translocate via a catch and release mechanism
Creators: name: Krishnamurthy, Srinath
name: Sardis, Marios-Frantzeskos
name: Eleftheriadis, Nikolaos
name: Chatzi, Katerina E.
name: Smit, Jochem H.
name: Karathanou, Konstantina
name: Gouridis, Giorgos
name: Portaliou, Athina G.
name: Bondar, Ana-Nicoleta
name: Karamanou, Spyridoula
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: translocase
subject: protein secretion
subject: SecA
subject: SecYEG channel
subject: HDX-MS
subject: smFRET
subject: molecular dynamics
subject: signal peptide
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie

description: Protein machines undergo conformational motions to interact with and manipulate polymeric substrates. The Sec translocase promiscuously recognizes, becomes activated, and secretes >500 non-folded preprotein clients across bacterial cytoplasmic membranes. Here, we reveal that the intrinsic dynamics of the translocase ATPase, SecA, and of preproteins combine to achieve translocation. SecA possesses an intrinsically dynamic preprotein clamp attached to an equally dynamic ATPase motor. Alternating motor conformations are finely controlled by the γ-phosphate of ATP, while ADP causes motor stalling, independently of clamp motions. Functional preproteins physically bridge these independent dynamics. Their signal peptides promote clamp closing; their mature domain overcomes the rate-limiting ADP release. While repeated ATP cycles shift the motor between unique states, multiple conformationally frustrated prongs in the clamp repeatedly “catch and release” trapped preprotein segments until translocation completion. This universal mechanism allows any preprotein to promiscuously recognize the translocase, usurp its intrinsic dynamics, and become secreted.
title: Ladies' man
Creators: name: Langage, Langues Et Cultures D'Afrique
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: anthropological_linguistics
subject: Poetry
subject: Beja
subject: bej
subject: Annotation

description: Recording session done by the collector/researcher in Khartoum. Were present : the collector/researcher, and the speaker.
description: Poem about a messenger sent by women to a ladies' man.
description: Conforms to: Leipzig Glossing Rules
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Optimal state space reconstruction via Monte Carlo decision tree search
Creators: name: Kraemer, K. Hauke
name: Gelbrecht, Maximilian
name: Pavithran, Induja
name: Sujith, R. I.
name: Marwan, Norbert
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: State space reconstruction
subject: Embedding
subject: Optimization
subject: Time series analysis
subject: Causality
subject: Prediction
subject: Recurrence analysis
subject: 500 Naturwissenschaften und Mathematik::510 Mathematik::510 Mathematik

description: A novel idea for an optimal time delay state space reconstruction from uni- and multivariate time series is presented. The entire embedding process is considered as a game, in which each move corresponds to an embedding cycle and is subject to an evaluation through an objective function. This way the embedding procedure can be modeled as a tree, in which each leaf holds a specific value of the objective function. By using a Monte Carlo ansatz, the proposed algorithm populates the tree with many leafs by computing different possible embedding paths and the final embedding is chosen as that particular path, which ends at the leaf with the lowest achieved value of the objective function. The method aims to prevent getting stuck in a local minimum of the objective function and can be used in a modular way, enabling practitioners to choose a statistic for possible delays in each embedding cycle as well as a suitable objective function themselves. The proposed method guarantees the optimization of the chosen objective function over the parameter space of the delay embedding as long as the tree is sampled sufficiently. As a proof of concept, we demonstrate the superiority of the proposed method over the classical time delay embedding methods using a variety of application examples. We compare recurrence plot-based statistics inferred from reconstructions of a Lorenz-96 system and highlight an improved forecast accuracy for map-like model data as well as for palaeoclimate isotope time series. Finally, we utilize state space reconstruction for the detection of causality and its strength between observables of a gas turbine type thermoacoustic combustor.
Detection and characterization of Lactobacillus spp. in the porcine seminal plasma and their influence on boar semen quality
Creators: name: Schulze, Martin
name: Schäfer, Jana
name: Simmet, Christian
name: Jung, Markus
name: Gabler, Christoph
Publisher: name: Freie Universität Berlin
Year: 2018
Subjects: subject: semen
subject: sperm
subject: lactobacillus
subject: pathogen motility
subject: mitochondria
subject: lactic acid bacteria
subject: sequence databases
subject: swine
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten
subject: 500 Naturwissenschaften und Mathematik::590 Tiere (Zoologie)::590 Tiere (Zoologie)

description: The presence of pathogenic bacteria in ejaculates has been a topic in boar semen preservation over the last decades. Since little information is available on commensal bacteria in boar semen, the aim of the present study was to identify commensal lactobacilli in fresh cryopreserved boar semen and to examine their influence on boar semen quality. Therefore, 111 boar ejaculates were investigated for the presence of Lactobacillus species. Thirty samples (27%) contained viable Lactobacillus species (e.g. L. amylovorus, L. animalis, L. reuteri and Weisella minor). L. animalis and L. buchneri DSM 32407 (isolated from the bovine uterus) qualified for further examinations based on their growth rate in six antibiotic-free boar semen extenders. After a 120 min short-term incubation with an antibiotic-free BTS-extender, progressive motility was diminished (P = 0.001) upon addition of 105 and 106 colony forming units (CFU/mL) L. animalis. The supplementation with L. buchneri DSM 32407 had no significant (P > 0.05) influence on sperm quality during short-term co-incubation. After 168 h long-term co-incubation, motility analysis revealed a negative (P = 0.026) impact of 105 CFU/mL L. buchneri DSM 32407. A concentration- and storage-dependent effect is particularly obvious (P < 0.001) using 106 CFU/mL L. buchneri DSM 32407. Most notably, the thermo-resistance (TRT) for 106 CFU/mL L. buchneri DSM 32407 (P = 0.001) was inferior to BTS with and without gentamicin after 72 and 168 h of semen co-incubation. The supplementation of 105 CFU/mL L. buchneri DSM 32407 impaired progressive motility to a lesser extent. The percentage of mitochondrially active spermatozoa after 96 h (P = 0.009) and membrane-intact spermatozoa after 168 h (P < 0.001) was lower when 106 CFU/mL L. buchneri DSM 32407 were suspended compared with all other groups. Finally, the addition of L. buchneri DSM 32407 to BTS-extended boar semen had no competitive effect on the total amount of bacteria 48 h after co-incubation. In summary, the present study demonstrated that there are Lactobacillus species present in the porcine seminal plasma, which can be cultivated using standard procedures. However, long-term co-incubation of lactic acid bacteria with spermatozoa had a negative influence on spermatozoa.
title: Intravitreales Interferon α-2a für die Behandlung der chronisch-rezidivierenden Chorioretinopathia centralis serosa (CCS)
Creators: name: Schoen, Katharina
name: Pillunat, L.E.
name: Matthé, E.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Chorioretinopathia centralis serosa (CCS) ist eine multifaktorielle, insbesondere bei Männern im erwerbsfähigen Alter auftretende Erkrankung, die durch Exsudation von Flüssigkeit aus Aderhautgefäßen charakterisiert ist. Dabei kommt es zur Abhebung der neurosensorischen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
title: Lokale Therapie bei RCS – Was ist sinnvoll?
Creators: name: Matthé, Egbert
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Chorioretinopathia centralis serosa (CCS) ist eine häufige Erkrankung, die durch Exsudation von Flüssigkeit aus Aderhautgefäßen charakterisiert ist und zur Abhebung der neurosensorischen Retina und/oder des retinalen Pigmentepithels führt. Im Januar 2018 wurde[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
Healthcare workers’ perspectives on participatory system dynamics modelling and simulation: designing safe and efficient hospital pharmacy dispensing systems together
Creators: name: Shire, Mohammed Ibrahim
name: Gyuchan Thomas Jun
name: Robinson, Stewart
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: With increasingly complex safety-critical systems like healthcare being developed and managed, there is a need for a tool that permits decision-makers to better understand the complexity, test various strategies and guide effective changes. System Dynamics (SD) modelling is an effective approach that can aid strategic decision-making in healthcare systems but has been underutilised partly due to the challenge of engaging healthcare stakeholders in the modelling process. This paper, therefore, investigates the applicability of a participatory SD approach based on healthcare workers’ perspectives on ease of use (usability) and usefulness (utility). The study developed an interactive simulation dashboard platform which facilitated participatory simulation for exploring various hospital pharmacy staffing level arrangements and their impacts on interruptions, fatigue, workload, rework, productivity and safety. The findings reveal that participatory SD approach can enhance team learning by converging on a shared mental model, aid decision-making and identifying trade-offs. The implications of these findings are discussed as well as experience and lessons learned on modelling facilitation. Practitioner Summary: This paper reports the perspectives of healthcare workers, who were engaged with a participatory system dynamics modelling and simulation process for hospital pharmacy staffing level management. Evaluative feedback revealed that the participatory SD approach can be a valuable tool for participatory ergonomics by helping the participants gain a deeper understanding of the complex dynamic interactions between workload, rework, safety and efficiency. Abbreviations: SD: system dynamics; ETTO: efficiency-thoroughness trade-off
title: Ozurdex für das entzündliche Makulaödem – wie viele Injektionen verträgt ein Auge?
Creators: name: Wittig, Dierk
name: Pillunat, L.E.
name: Matthé, E.
name: Sandner, D.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Seit 2010 ist das intravitreal implantierbare Langzeit-Dexamethasonpräparat (Ozurdex®) erhältlich. Neben den zugelassenen Anwendungsgebieten (Makulaödem nach retinalen Venenverschlüssen, diabetischer Retinopathie und nicht infektiöse Uveitis posterior) bestehen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
title: Therapieoptionen zur Behandlung des Sekundärglaukoms intraokularer Tumore nach Radiatio
Creators: name: Riechardt, Aline
name: Seibel, I.
name: Zeitz, O.
name: Joussen, A.M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Heutzutage sind wir aufgrund des medizinischen Fortschritts in der Lage Tumore zu behandeln, die früher eine sichere Enukleationsindikation dargestellt hätten. Aufgrund der hohen lokalen Tumorkontrollrate der Protontherapie und der Brachytherapie von bis zu 98% stellt das[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
Synthesis and biological activity of ethyl 2-(5-methyl-3-arylisoxazole-4-carboxamido)-4-alkylthiazole-5-carboxylate
Creators: name: Wang, Wei
name: Wang, Lie-Ping
name: Mao, Min-Zhen
name: Zhang, Xiao-Guang
name: Zheng, Xiao-Rui
name: Huang, Xiao-Ying
name: Xue, Chao
name: Ning, Bin-Ke
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: A series of novel ethyl 2-(5-methyl-3-arylisoxazole-4-carboxamido)-4-alkylthiazole-5-carboxylates I-1-6 were synthesized. The structures of all target compounds were characterized by 1H NMR, 13C NMR, IR, MS and elemental analyses. Their fungicidal and herbicidal activities were evaluated. The results of preliminary bioassays show that the title compounds I-4 possess 20–50% inhibition against most of the tested plants at the dosage of 150 g ai/ha, while the title compounds I-1-5 possess 32–58% inhibition against FusaHum graminearum, Thanatephorus cucumeris, Botrytis cinereapers and Fusarium oxysporum in vitro at the concentration of 100 mg/L.
Validation of a new prognostic model to predict short and medium-term survival in patients with liver cirrhosis
Creators: name: Dziodzio, Tomasz
name: Öllinger, Robert
name: Schöning, Wenzel
name: Rothkäppel, Antonia
name: Nikolov, Radoslav
name: Juraszek, Andrzej
name: Ritschl, Paul V.
name: Stockmann, Martin
name: Pratschke, Johann
name: Jara, Maximilian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: End-stage liver disease
subject: LiMAx®
subject: MELD
subject: Mortality risk
subject: Prognosis
subject: Survival
subject: Survival scores
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: MELD score and MELD score derivates are used to objectify and grade the risk of liver-related death in patients with liver cirrhosis. We recently proposed a new predictive model that combines serum creatinine levels and maximum liver function capacity (LiMAx®), namely the CreLiMAx risk score. In this validation study we have aimed to reproduce its diagnostic accuracy in patients with end-stage liver disease. Methods: Liver function of 113 patients with liver cirrhosis was prospectively investigated. Primary end-point of the study was liver-related death within 12 months of follow-up. Results: Alcoholic liver disease was the main cause of liver disease (n = 51; 45%). Within 12 months of follow-up 11 patients (9.7%) underwent liver transplantation and 17 (15.1%) died (13 deaths were related to liver disease, two not). Measures of diagnostic accuracy were comparable for MELD, MELD-Na and the CreLiMAx risk score as to power in predicting short and medium-term mortality risk in the overall cohort: AUROCS for liver related risk of death were for MELD [6 months 0.89 (95% CI 0.80–0.98) p
Simulation of Auger decay dynamics in the hard X-ray regime: HCl as a showcase
Creators: name: Goldsztejn, G.
name: Guillemin, R.
name: Marchenko, T.
name: Travnikova, O.
name: Ceolin, D.
name: Journel, L.
name: Simon, M.
name: Piancastelli, M. N.
name: Püttner, Ralph
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: Auger decay dynamics
subject: hard X-ray regime
subject: simulation
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Auger decay after photoexcitation or photoemission of an electron from a deep inner shell in the hard X-ray regime can be rather complex, implying a multitude of phenomena such as multiple-step cascades, post-collision interaction (PCI), and electronic state-lifetime interference. Furthermore, in a molecule nuclear motion can also be triggered. Here we discuss a comprehensive theoretical method which allows us to analyze in great detail Auger spectra measured around an inner-shell ionization threshold. HCl photoexcited or photoionized around the deep Cl 1s threshold is chosen as a showcase. Our method allows calculating Auger cross sections considering the nature of the ground, intermediate and final states (bound or dissociative), and the evolution of the relaxation process, including both electron and nuclear dynamics. In particular, we show that we can understand and reproduce a so-called experimental 2D-map, consisting of a series of resonant Auger spectra measured at different photon energies, therefore obtaining a detailed picture of all above-mentioned dynamical phenomena at once.
title: Unsere Erfahrungen mit der neuen Ultraweitwinkel-Angiographie und echtfarb-LED-Bildgebung (Zeiss Clarus 700).
Creators: name: Gläser, Sandra
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Die Fundusbildgebung hat sich in den letzten Jahrzehnten rasant entwickelt. Weitwinkel- und Ultraweitwinkelgeräte werden immer beliebter. Unter Weitwinkelbildgebung versteht man Aufnahmen von mehr als 50 Grad, Ultraweitwinkelsysteme ermöglichen Aufnahmen von über 200 Grad. Mit dem Clarus[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
title: Netzhautablösung bei Myopie
Creators: name: Meier, Petra
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Eine Refraktionsanomalie mit einem sphärischen Äquivalent von größer/gleich –0.5 dptr wird als Myopie bezeichnet, eine hohe Myopie liegt bei einem sphärischen Äquivalent größer 6 dptr und/oder einer Achsenlänge von 26.5 mm vor. Werden zusätzlich[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
Synthesis and Biological Activity of Ethyl 2-(5-methyl-3-arylisoxazole-4-carboxamido)-4-alkylthiazole-5-carboxylate
Creators: name: Wang, Wei
name: Wang, Lie-Ping
name: Mao, Min-Zhen
name: Zhang, Xiao-Guang
name: Zheng, Xiao-Rui
name: Huang, Xiao-Ying
name: Xue, Chao
name: Ning, Bin-Ke
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: A series of novel ethyl 2-(5-methyl-3-arylisoxazole-4-carboxamido)-4-alkylthiazole-5-carboxylates I-1-6 were synthesized. The structures of all target compounds were characterized by 1H NMR, 13C NMR, IR, MS and elemental analyses. Their fungicidal and herbicidal activities were evaluated. The results of preliminary bioassays show that the title compounds I-4 possess 20–50% inhibition against most of the tested plants at the dosage of 150 g ai/ha, while the title compounds I-1-5 possess 32–58% inhibition against FusaHum graminearum, Thanatephorus cucumeris, Botrytis cinereapers and Fusarium oxysporum in vitro at the concentration of 100 mg/L.
title: Eine Diagnose kommt selten allein
Creators: name: Zajonz, Anne-Catherine
name: Riemer, O.
name: Witt, S.
name: von Below, H.
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: Ein 36-jähriger männlicher Patient stellte sich 04/17 erstmalig in augenärztlicher Praxis mit links Visusverlust auf 0,16 vor. Es zeigte sich links ein hinterer Polstar, welcher im Mai 2017 komplikationslos ambulant versorgt werden konnte. Im Verlauf stellt sich der Patient mit links[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft
Perception and manipulation for robot-assisted dressing
Creators: name: Zhang, Fan
Publisher: name: Imperial College London
Year: 2020

description: Assistive robots have the potential to provide tremendous support for disabled and elderly people in their daily dressing activities. This thesis presents a series of perception and manipulation algorithms for robot-assisted dressing, including: garment perception and grasping prior to robot-assisted dressing, real-time user posture tracking during robot-assisted dressing for (simulated) impaired users with limited upper-body movement capability, and finally a pipeline for robot-assisted dressing for (simulated) paralyzed users who have lost the ability to move their limbs. First, the thesis explores learning suitable grasping points on a garment prior to robot-assisted dressing. Robots should be endowed with the ability to autonomously recognize the garment state, grasp and hand the garment to the user and subsequently complete the dressing process. This is addressed by introducing a supervised deep neural network to locate grasping points. To reduce the amount of real data required, which is costly to collect, the power of simulation is leveraged to produce large amounts of labeled data. Unexpected user movements should be taken into account during dressing when planning robot dressing trajectories. Tracking such user movements with vision sensors is challenging due to severe visual occlusions created by the robot and clothes. A probabilistic real-time tracking method is proposed using Bayesian networks in latent spaces, which fuses multi-modal sensor information. The latent spaces are created before dressing by modeling the user movements, taking the user's movement limitations and preferences into account. The tracking method is then combined with hierarchical multi-task control to minimize the force between the user and the robot. The proposed method enables the Baxter robot to provide personalized dressing assistance for users with (simulated) upper-body impairments. Finally, a pipeline for dressing (simulated) paralyzed patients using a mobile dual-armed robot is presented. The robot grasps a hospital gown naturally hung on a rail, and moves around the bed to finish the upper-body dressing of a hospital training manikin. To further improve simulations for garment grasping, this thesis proposes to update more realistic physical properties values for the simulated garment. This is achieved by measuring physical similarity in the latent space using contrastive loss, which maps physically similar examples to nearby points.
Carbon Monoxide on Oxide Surfaces: Facet-Specific Donation and Backdonation Effects on TiO2 Anatase Nanoparticles
Creators: name: Tabacchi, Gloria
name: Deiana, Chiara
name: Martra, Gianmario
name: Pellegrino, Francesco
name: Narbey, Stéphanie
name: Fois, Ettore
Publisher: name: figshare
Year: 2017
Subjects: subject: 30301 Chemical Characterisation of Materials
subject: FOS: Chemical sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: 30602 Chemical Thermodynamics and Energetics
subject: 30603 Colloid and Surface Chemistry
subject: Computational Chemistry
subject: Inorganic Chemistry
subject: 30299 Inorganic Chemistry not elsewhere classified
subject: Molecular Physics
subject: 30699 Physical Chemistry not elsewhere classified
subject: 30304 Physical Chemistry of Materials
subject: 30701 Quantum Chemistry
subject: 30206 Solid State Chemistry
subject: 30306 Synthesis of Materials
subject: 30799 Theoretical and Computational Chemistry not elsewhere classified
subject: 30307 Theory and Design of Materials
subject: 30207 Transition Metal Chemistry
subject: Computational Physics
subject: 20403 Condensed Matter Modelling and Density Functional Theory
subject: FOS: Physical sciences
subject: Condensed Matter Physics
subject: 20499 Condensed Matter Physics not elsewhere classified
subject: 20406 Surfaces and Structural Properties of Condensed Matter
subject: 100708 Nanomaterials
subject: FOS: Nanotechnology
subject: 100712 Nanoscale Characterisation
subject: 100799 Nanotechnology not elsewhere classified

description: Green open access version of the paper:On the Simple Complexity of Carbon Monoxide on Oxide Surfaces: Facet-Specific Donation and Backdonation Effects Revealed on TiO2 Anatase Nanoparticles
Published in: ChemPhysChem 2016, 17, 1956-1960. DOI: 10.1002/cphc.201600284
which should be cited to refer to this work.Related material can be found at the links below (REFERENCES)
Link to the VoR:http://dx.doi.org/10.1002/cphc.201600284

Supporting data:
https://figshare.com/articles/Carbon_Monoxide_on_TiO2_anatase_nanoparticles_IR_spectra_and_donation-backdonation_effects/3428198

blog post explaining this research:https://yourmoleculardreams.blog/2016/07/25/tio2_co_bond/

popular summary of the paper: https://goo.gl/4PZ7vx
slides presentation:https://figshare.com/articles/titanium_dioxide_nanoparticles_the_importance_of_shape_and_exposed_facets_in_surface-molecule_interactions/4056189
Infographics:https://figshare.com/articles/TiO2_nanoparticles_surfaces_binding_of_carbon_monoxide_explained/3464075

High-resolution figures:https://figshare.com/articles/Carbon_Monoxide_adsorbed_on_the_TiO2_anatase_101_and_110_facets/3436766

additional images:https://figshare.com/articles/Binding_of_CO_on_TiO2_nanoparticles/3437654
Rapid and efficient thiocyanation of phenols, indoles, and anilines in 1,1,1,3,3,3-hexafluoro-2-propanol under ultrasound irradiation
Creators: name: Wang, Zhonghao
name: Wang, Liang
name: Chen, Qun
name: He, Ming-yang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biophysics
Biochemistry
Space Science
Medicine
Molecular Biology
Neuroscience
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Marine Biology
Mental Health
Computational Biology

description: An efficient ultrasound-promoted thiocyanation of phenols, indoles, and anilines in the presence of N-chlorosuccinimide and NH4SCN using 1,1,1,3,3,3-hexafluoro-2-propanol as the solvent has been developed. The major features of the present protocol include the mild reaction conditions, short reaction times, good to excellent yields, and broad substrate scope. Moreover, scale-up synthesis can be achieved and the solvent can be easily recovered and reused.
title: Therapie-Planung für das diabetische Makulaödem mit Hilfe von Biomarkern
Creators: name: Engelmann, Katrin
Publisher: name: German Medical Science GMS Publishing House
Year: 2020
Subjects: subject: 610 Medical sciences; Medicine

description: In der Medizin wird zunehmend stark die Individualisierung von Behandlungen gefordert. Die Behandlung des Diabetes mellitus (DM) ist ein typisches Beispiel für eine bereits stark individualisierte oder personalisierte Medizin. Serologische Biomarker werden bereits heute eingesetzt (HbA1c) und sie[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung 2019 der Sächsischen Augenärztlichen Gesellschaft