cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Facile development, characterization, and optimization of new metformin-loaded nanocarrier system for efficient colon cancer adjunct therapy
Creators: name: Kholoud Arafa
name: Rehab N. Shamma
name: El-Gazayerly, Omaima N.
name: El-Sherbiny, Ibrahim M.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Purpose: Metformin hydrochloride (MF) repurposing as adjuvant anticancer therapy for colorectal cancer (CRC) proved effective. Several studies attempted to develop MF-loaded nanoparticles (NPs), however the entrapment efficiency (EE%) was poor. Thus, the present study aimed at the facile development of a new series of chitosan (CS)-based semi-interpenetrating network (semi-IPN) NPs incorporating Pluronic® nanomicelles as nanocarriers for enhanced entrapment and sustained release of MF for efficient treatment of CRC. Methods: The NPs were prepared by ionic gelation and subsequently characterized using FTIR, DSC, TEM, and DLS. A full factorial design was also adopted to study the effect of various formulation variables on EE%, particle size, and zeta-potential of NPs. Results: NPs had a spherical shape and a mean particle size ranging between 135 and 220 nm. FTIR and DSC studies results were indicative of successful ionic gelation with the drug being dispersed in its amorphous form within CS-Pluronic® matrix. Maximum EE% reaching 57.00 ± 12.90% was achieved using Pluronic®-123 based NPs. NPs exhibited a sustained release profile over 48 h. The MF-loaded NPs sensitized RKO CRC cells relative to drug alone. Conclusion: The reported results highlighted the novel utility of the developed NPs in the arena of colon cancer treatment.
Additional file 1 of Camelot: a computer-automated micro-extensometer with low-cost optical tracking
Creators: name: Trozzi, Nicola
name: Wodniok, Wiktoria
name: Kelly-Bellow, Robert
name: Meraviglia, Andrea
name: Chételat, Aurore
name: Adkins, Nova
name: Lane, Brendan
name: Smith, Richard S.
name: Kwiatkowska, Dorota
name: Majda, Mateusz
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1. Table S1. Comparison of microextensometer systems for plant biomechanics. This table compares actuation, force sensing, deformation tracking, software integration, and cost across recent extensometer setups. The Camelot system (Trozzi et al., 2025) is presented alongside ACME (Robinson et al., 2017), Bidhendi et al. (2020), Lee et al. (2024), Chen et al. (2024), and Hofhuis et al. (2016), showing differences in precision, complexity, and affordability.
The cosmic QCD phase transition with dense matter and its gravitational waves from holography
Creators: name: Ahmadvand, M.
name: Fadafan, K. Bitaghsir
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Consistent with cosmological constraints, there are scenarios with the large lepton asymmetry which can lead to the finite baryochemical potential at the cosmic QCD phase transition scale. In this paper, we investigate this possibility in the holographic models. Using the holographic renormalization method, we find the first order Hawking-Page phase transition, between Reissner-Nordstr$\rm\ddot{o}$m AdS black hole and thermal charged AdS space, corresponding to the de/confinement phase transition. We obtain the gravitational wave spectra generated during the evolution of bubbles for a range of the bubble wall velocity and examine the reliability of the scenarios and consequent calculations by gravitational wave experiments.
description: 18 pages , 4 figures, references and new discussions added, accepted to be published in Phys. Lett. B
Memories of Singapore
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Albert was in Singapore when it fell to the Japanese. He ended up in Changi Jail until the end of the war.
title: ADCO, Boursier de Cîteaux : comptes (1489-1493) (11 H 1166), f. 00404
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédéric
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Corpus Burgundiae Medii Aevi
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes

description: Boursier de Cîteaux : comptes (1489-1493), Archives départementales de la Côte-d'Or, (11 H 1166). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Boursier de Cîteaux : comptes (1489-1493), Archives départementales de la Côte-d'Or, (11 H 1166), f. 00404, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Performance measurement of HARPO: a Time Projection Chamber as a gamma-ray telescope and polarimeter
Creators: name: Gros, P.
name: Amano, S.
name: Attié, D.
name: Baron, P.
name: Baudin, D.
name: Bernard, D.
name: Bruel, P.
name: Calvet, D.
name: Colas, P.
name: Daté, S.
name: Delbart, A.
name: Frotin, M.
name: Geerebaert, Y.
name: Giebels, B.
name: Götz, D.
name: Hashimoto, S.
name: Horan, D.
name: Kotaka, T.
name: Louzir, M.
name: Magniette, F.
name: Minamiyama, Y.
name: Miyamoto, S.
name: Ohkuma, H.
name: Poilleux, P.
name: Semeniouk, I.
name: Sizun, P.
name: Takemoto, A.
name: Yamaguchi, M.
name: Yonamine, R.
name: Wang, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: High Energy Physics - Experiment (hep-ex)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We analyse the performance of a gas time projection chamber (TPC) as a high-performance gamma-ray telescope and polarimeter in the e$^+$e$^-$ pair creation regime. We use data collected at a gamma-ray beam of known polarisation. The TPC provides two orthogonal projections $(x,z)$ and $(y,z)$ of the tracks induced by each conversion in the gas volume. We use a simple vertex finder in which vertices and pseudo-tracks exiting from them are identified. We study the various contributions to the single-photon angular resolution using Monte Carlo simulations and compare them with the experimental data and find that they are in excellent agreement. The distribution of the azimutal angle of pair conversions shows a bias due to the non-cylindrical-symmetric structure of the detector. This bias would average out for a long duration exposure on a space mission, but for this pencil-beam characterisation we have ensured its accurate simulation by a double systematics control scheme, data taking with the detector rotated at several angles with respect to the beam polarisation direction and systematics control with a non-polarised beam. We measure, for the first time, the polarisation asymmetry of a linearly polarised gamma-ray beam in the low energy pair creation regime. This sub-GeV energy range is critical for cosmic sources as their spectra are power laws which fall quickly as a function of increasing energy. This work could pave the way to extending polarised gamma-ray astronomy beyond the MeV energy regime.
description: Submitted to Astroparticle Physics
Correcting the extended-source calibration for the Herschel-SPIRE Fourier-Transform Spectrometer
Creators: name: Valtchanov, Ivan
name: Hopwood, R.
name: Bendo, G.
name: Benson, C.
name: Conversi, L.
name: Fulton, T.
name: Griffin, M. J.
name: Joubaud, T.
name: Lim, T.
name: Lu, N.
name: Marchili, N.
name: Makiwa, G.
name: Meyer, R. A.
name: Naylor, D. A.
name: North, C.
name: Papageorgiou, A.
name: Pearson, C.
name: Polehampton, E. T.
name: Scott, J.
name: Schulz, B.
name: Spencer, L. D.
name: van der Wiel, M. H. D.
name: Wu, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We describe an update to the Herschel-SPIRE Fourier-Transform Spectrometer (FTS) calibration for extended sources, which incorporates a correction for the frequency-dependent far-field feedhorn efficiency, $η_\mathrm{FF}$. This significant correction affects all FTS extended-source calibrated spectra in sparse or mapping mode, regardless of the spectral resolution. Line fluxes and continuum levels are underestimated by factors of 1.3-2 in the Spectrometer Long-Wavelength band (SLW, 447-1018 GHz; 671-294 $μ$m) and 1.4-1.5 in the Spectrometer Short-Wavelength band (SSW, 944-1568 GHz; 318-191 $μ$m). The correction was implemented in the FTS pipeline version 14.1 and has also been described in the SPIRE Handbook since Feb 2017. Studies based on extended-source calibrated spectra produced prior to this pipeline version should be critically reconsidered using the current products available in the Herschel Science Archive. Once the extended-source calibrated spectra are corrected for $η_\mathrm{FF}$, the synthetic photometry and the broadband intensities from SPIRE photometer maps agree within 2-4% -- similar levels to the comparison of point-source calibrated spectra and photometry from point-source calibrated maps. The two calibration schemes for the FTS are now self-consistent: the conversion between the corrected extended-source and point-source calibrated spectra can be achieved with the beam solid angle and a gain correction that accounts for the diffraction loss.
description: 9 pages, 6 figures, 1 table, MNRAS in press
title: Η Ιταλία ως χώρα προέλευσης τουριστών στην Ελλάδα - Προβλέψεις αφίξεων
title: Italy as a country of origin of tourists in Greece. Arrival analysis - forecasts
titleType: AlternativeTitle
Creators: name: Καπούλας, Γεώργιος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: Τουρισμός
subject: Ελληνικός τουρισμός
subject: Ιταλία
subject: Προβλέψεις αφίξεων

description: Ο τουρισμός αποτελεί μία δραστηριότητα που σχετίζεται με πολλούς κλάδους της οικονομίας παγκοσμίως. Η περιγραφή του, ως ένας εξαιρετικά πολύπλευρος τομέας, πηγάζει από το γεγονός ότι απαιτεί τη συμβολή οικονομικών, κοινωνικών, πολιτιστικών και περιβαλλοντικών δεδομένων. Πλήθος ανθρώπων ανά τον κόσμο απασχολούνται στη βιομηχανία του τουρισμού, με την επίδρασή του στην παγκόσμια κοινωνικοοικονομική ζωή να είναι τεράστια. Για την Ελλάδα, ο τομέας του τουρισμού αποτελεί μία από τις σημαντικότερες βιομηχανίες της χώρας, αφού η συμβολή του στην απασχόληση και στη διαμόρφωση του ΑΕΠ τον καθιστά απαραίτητο για την οικονομική ευημερία του κράτους. Είναι γεγονός πως η Ελλάδα αποτελεί αγαπημένο τουριστικό προορισμό, με την εκάστοτε πολιτική ηγεσία και τους αρμόδιους φορείς να αναζητούν συνεχώς στρατηγικές ανάπτυξης και περαιτέρω εξέλιξης του κλάδου. Σκοπός της παρούσας Διπλωματικής Εργασίας είναι η ανάλυση της Ιταλίας ως χώρας προέλευσης τουριστών στην Ελλάδα και η διεξαγωγή προβλέψεων με τη βοήθεια προγράμματος, της εισερχόμενης κίνησης των Ιταλών τουριστών στη χώρα μας τα επόμενα έτη. Αποτελείται από έξι κεφάλαια, στα οποία αρχικά γίνεται ανάλυση του Ελληνικού Τουρισμού, παραθέτοντας στοιχεία για τις επιδράσεις του στην κοινωνικοοικονομική ζωή της χώρας, ενώ στη συνέχεια καταγράφονται οι σχέσεις της Ελλάδας με την Ιταλία, ξεκινώντας από τα πρώτα χρόνια της αρχαιότητας και καταλήγοντας στο σήμερα και την πολύ επίπεδη συνεργασία των δύο χωρών. Ακολουθεί η διεξαγωγή προβλέψεων των αφίξεων των Ιταλών τουριστών τα επόμενα έτη με τη βοήθεια προγράμματος, λαμβάνοντας ως δεδομένα τον αριθμό των αφίξεων των Ιταλών ανά μήνα προηγούμενων ετών, αντλώντας στοιχεία που καταγράφηκαν από την Τράπεζα της Ελλάδος και την Εθνική Στατιστική Υπηρεσία. Τέλος, διατυπώνονται τα συμπεράσματα της μελέτης και οι προτάσεις τουριστικής πολιτικής για την ανάπτυξη και την εξέλιξη του ελληνικού τουριστικού προϊόντος.
The solid-state structures of organic salts formed by calix[4]arene dihydroxyphosphonic acid with nucleic bases cations: adeninium, cytosinium, guaninium and uracilium
Creators: name: Shkurenko, Aleksander
name: Lazar, Adina N.
name: Collard, Dominique
name: Navaza, Alda
name: Beomjoon Kim
name: Tauran, Yannick
name: Perret, Florent
name: Journet-Gautier, Catherine
name: Coleman, Anthony W.
name: Suwinska, Kinga
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Calix[4]arene dihydroxyphosphonic acid has been demonstrated to possess an interesting range of biological properties, including atypical anti-cancer activity. The robustness of calix[4]arene dihydroxyphosphonic acid and its ubiquitous dimeric motif offers perspectives for pre-defined solid state complexation with small molecules. In the current article we describe co-crystals (organic salts) of calix[4]arene dihydroxyphosphonic acid with four nucleic base cations: adeninium, cytosinium, guaninium and uracilium. A number of characteristic interactions between the components in the four co-crystals are pointed out also using the Hirshfeld surface analysis. All the four co-crystals are based on layers of calix[4]arene dimers, alternating with layers of nucleic acid molecules. Two of the reported crystal structures (cytosinium and guaninium) are 1D channel-type structures, while the two others (adeninium and uracilium) represent 2D channel-type structures. In three out of four reported structures, interactions between the cations of nucleic bases are present generating 1D chains of cations. A constant motif is that the nucleic base is present in a type of cavity formed by one aromatic ring and a phosphonic acid moiety.
Η κερδοφορία των αμερικανικών και ευρωπαϊκών τραπεζών
Creators: name: Κανελλοπούλου, Μαρία
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: Αμερικανικές και ευρωπαϊκές τράπεζες
subject: Κερδοφορία
subject: Τραπεζικοί και μακροοικονομικοί παράγοντες
subject: Ανάλυση
subject: American and european banks
subject: Profitability
subject: Bank-specific and macroeconomic determinants
subject: Analysis

description: Ο βασικός στόχος της διπλωματικής εργασίας είναι η μελέτη τραπεζικών και μακροοικονομικών παραγόντων που επιδρούν στη κερδοφορία των Αμερικανικών και Ευρωπαϊκών τραπεζών τη χρονική περίοδο 1999 - 2020 (22 έτη). Ως μέτρο ποσοτικοποίησης της κερδοφορίας των τραπεζών αξιοποιήθηκε ο δείκτης απόδοσης του ενεργητικού (ROA). Η εμπειρική μελέτη βασίστηκε σε ένα μη ισορροπημένο πάνελ δεδομένων και το δείγμα της γραμμικής παλινδρόμησης αποτελείται από 80 ενεργές τράπεζες (50 Αμερικανικές και 30 Ευρωπαϊκές τράπεζες της Γερμανίας, Γαλλίας, Ισπανίας, Ιταλίας και Ολλανδίας) από το 1999 έως και το 2020. Βάσει των αποτελεσμάτων το μέγεθος των τραπεζών, το καθαρό επιτοκιακό περιθώριο και η ποσοστιαία μεταβολή χορήγησης δανείων ενός έτους επιδρούν θετικά στη κερδοφορία των εν λόγω τραπεζών. Αντίθετα, ο λόγος των μη εξυπηρετούμενων δανείων προς τα συνολικά δάνεια επιδρά αρνητικά στη κερδοφορία των τραπεζών. Από μακροοικονομική σκοπιά, η ποσοστιαία αύξηση του ΑΕΠ και η αύξηση των επιτοκίων ενισχύουν θετικά την απόδοση των τραπεζών. Επίσης, το αρχικό χρονικό διάστημα διαχωρίστηκε σε τέσσερα επιμέρους χρονικά διαστήματα (1999-2006, 2007-2009, 2010-2013, 2014-2020) για τη μελέτη της επίδρασης κάθε χρονικής περιόδου στη κερδοφορία των τραπεζών. Τέλος, εξετάστηκαν οι διαφορές μεταξύ των Αμερικανικών και Ευρωπαϊκών τραπεζών του δείγματος ως προς τους τραπεζικούς και μακροοικονομικούς παράγοντες μεταξύ 1999 και 2020, με στόχο τη διεξαγωγή καλύτερων συμπερασμάτων.
The Matroid Structure of Representative Triple Sets and Triple-Closure Computation
Creators: name: Hellmuth, Marc
name: Seemann, Carsten R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: The closure $\textrm{cl}(R)$ of a consistent set $R$ of triples (rooted binary trees on three leaves) provides essential information about tree-like relations that are shown by any supertree that displays all triples in $R$. In this contribution, we are concerned with representative triple sets, that is, subsets $R'$ of $R$ with $\textrm{cl}(R') = \textrm{cl}(R)$. In this case, $R'$ still contains all information on the tree structure implied by $R$, although $R'$ might be significantly smaller. We show that representative triple sets that are minimal w.r.t.\ inclusion form the basis of a matroid. This in turn implies that minimal representative triple sets also have minimum cardinality. In particular, the matroid structure can be used to show that minimum representative triple sets can be computed in polynomial time with a simple greedy approach. For a given triple set $R$ that "identifies" a tree, we provide an exact value for the cardinality of its minimum representative triple sets. In addition, we utilize the latter results to provide a novel and efficient method to compute the closure $\textrm{cl}(R)$ of a consistent triple set $R$ that improves the time complexity $\mathcal{O}(|R||L_R|^4)$ of the currently fastest known method proposed by Bryant and Steel (1995). In particular, if a minimum representative triple set for $R$ is given, it can be shown that the time complexity to compute $\textrm{cl}(R)$ can be improved by a factor up to $|R||L_R|$. As it turns out, collections of quartets (unrooted binary trees on four leaves) do not provide a matroid structure, in general.
Additional file 2 of Camelot: a computer-automated micro-extensometer with low-cost optical tracking
Creators: name: Trozzi, Nicola
name: Wodniok, Wiktoria
name: Kelly-Bellow, Robert
name: Meraviglia, Andrea
name: Chételat, Aurore
name: Adkins, Nova
name: Lane, Brendan
name: Smith, Richard S.
name: Kwiatkowska, Dorota
name: Majda, Mateusz
Publisher: name: figshare
Year: 2025
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 2. Figures S1–S7. Fig. S1 – Hardware components. Fig. S2 – 3D-printed parts. Fig. S3 – Setup configurations. Fig. S4 – Electronic layouts. Fig. S5 – Confocal setup. Fig. S6 – Inverted microscope setup. Fig. S7 – Confocal stretch series.
Tree-based solvers for adaptive mesh refinement code FLASH - I: gravity and optical depths
Creators: name: Wünsch, Richard
name: Walch, Stefanie
name: Dinnbier, František
name: Whitworth, Anthony P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We describe an OctTree algorithm for the MPI-parallel, adaptive mesh-refinement code {\sc FLASH}, which can be used to calculate the gas self-gravity, and also the angle-averaged local optical depth, for treating ambient diffuse radiation. The algorithm communicates to the different processors only those parts of the tree that are needed to perform the tree walk locally. The advantage of this approach is a relatively low memory requirement, important in particular for the optical depth calculation, which needs to process information from many different directions. This feature also enables a general tree-based radiation transport algorithm that will be described in a subsequent paper, and delivers excellent scaling up to at least 1500 cores. Boundary conditions for gravity can be either isolated or periodic, and they can be specified in each direction independently, using a newly developed generalisation of the Ewald method. The gravity calculation can be accelerated with the {\em adaptive block update} technique by partially re-using the solution from the previous time-step. Comparison with the {\sc Flash} internal multi-grid gravity solver shows that tree based methods provide a competitive alternative, particularly for problems with isolated or mixed boundary conditions. We evaluate several multipole acceptance criteria (MACs) and identify a relatively simple APE MAC which provides high accuracy at low computational cost. The optical depth estimates are found to agree very well with those of the {\sc RADMC-3D} radiation transport code, with the tree solver being much faster. Our algorithm is available in the standard release of the {\sc FLASH} code in version 4.0 and later.
description: 26 pages, 19 figures, 6 tables. Accepted by MNRAS
Treating $Z_c(3900)$ and $Z(4430)$ as the ground-state and first radially excited tetraquarks
Creators: name: Agaev, S. S.
name: Azizi, K.
name: Sundu, H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Exploration of the resonances $Z_c(3900)$ and $Z(4430)$ are performed by assuming that they are ground-state and first radial excitation of the same tetraquark with $J^{P}=1^{+}$. The mass and current coupling of the $ Z_c(3900)$ and $Z(4430)$ states are calculated using QCD two-point sum rule method by taking into account vacuum condensates up to eight dimensions. We investigate the vertices $Z_cM_hM_l$ and $ZM_hM_l$, with $M_h$ and $M_l $ being the heavy and light mesons, and evaluate the strong couplings $ g_{Z_cM_hM_l}$ and $g_{ZM_hM_l}$ using QCD sum rule on the light cone. The extracted couplings allow us to find the partial width of the decays $ Z_c(3900) \to J/ψπ; \,ψ^{\prime} π;\, η_c ρ$ and $Z(4430) \to ψ^{\prime} π;\, J/ψπ;\, η_c^{\prime}ρ;\, η_cρ$, which may help in comprehensive investigation of these resonances. We compare width of the decays of $Z_c(3900)$ and $Z(4430)$ resonances with available experimental data as well as existing theoretical predictions.
description: 12 Pages, 3 Figures and 5 Tables
Nutritional Deficiency Diseases in Goats: Understanding Effective Management Approaches
Creators: name: Komal1, Rishi kumar2*
Publisher: name: The Science world a Monthly e magazine
Year: 2024

description: Nutritional deficiencies in goats can lead to significant health issues, impacting growth, reproduction, and overall productivity. This article reviews the primary nutritional deficiencies observed in goats, including their causes, clinical signs, and management strategies. Key deficiencies discussed include those of vitamins A, D, and E, as well as macro and micronutrients such as calcium, phosphorus, selenium, and copper. Understanding these deficiencies is crucial for effective herd management and improving the health and productivity of goats.
title: Ψυχρή εφοδιαστική αλυσίδα
title: Cold supply chain
titleType: AlternativeTitle
Creators: name: Ντανοβασίλης, Γεώργιος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: Ψυχρή εφοδιαστική αλυσίδα

description: Στην παρούσα μεταπτυχιακή διατριβή παρουσιάζονται, περιγράφονται και αναλύεται ο κλάδος της Ψυχρής Εφοδιαστικής Αλυσίδας στην σύγχρονη εποχή. Τόσο στην Ελλάδα όσο και στο Διεθνή χώρο υπάρχει μια αυξανόμενη ζήτηση για ασφαλή αλλά και ποιοτικά προϊόντα. Στο συγκεκριμένο πόνημα γίνεται αναφορά στις τρέχουσες τεχνολογικές τάσεις και έρευνες που βρίσκουν εφαρμογή στον κλάδο της Ψυχρής Εφοδιαστικής Αλυσίδας. Οι νέες αυτές τεχνολογίες ως κύριο στόχο έχουν τη μείωση του κόστους κατά μήκος της Ψυχρής Εφοδιαστικής Αλυσίδας και τη διασφάλιση της ποιότητας και της ασφάλειας των τροφίμων, μέχρι την τελική τους κατανάλωση. Σκοπός της παρούσας εργασίας είναι η επισήμανση της ύπαρξης της συγκεκριμένης Εφοδιαστικής Αλυσίδας για ευπαθή προϊόντα (φάρμακα, λαχανικά, κρέατα) και η ανάλυση των διαδικασιών που ακολουθούνται. Βασικό χαρακτηριστικό είναι η δημιουργία και η εφαρμογή όλων των διαδικασιών και λειτουργιών που θα οδηγήσουν στην ελαχιστοποίηση φαινομένων όπως η αλλοίωση τροφίμων. Τέλος οι σύγχρονες τεχνολογικές καινοτομίες έχουν βοηθήσει στην δημιουργία μηχανισμού ελέγχου, διατήρησης και συντήρησης των απαραίτητων συνθηκών για την διατήρηση και διασφάλιση της υγιεινής κατά την μεταφορά και αποθήκευση.
Colourimetric and fluorimetric metal ion chemosensor based on a benzimidazole functionalised Schiff base
Creators: name: Horak, Ema
name: Vianello, Robert
name: Hranjec, Marijana
name: Steinberg, Ivana Murković
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Herein we present the interaction of benzimidazole based Schiff base 1 with different metal ions studied by absorption and fluorescence spectroscopies and computational modelling. Compound 1 exhibits changes in spectroscopic properties upon chelation with specific metal ions. Its strong absorption band at 425 nm is significantly red shifted (Δλ = 30 nm) only upon the complexation with Al3+, an effect observable by a naked eye as a colour change from light- to dark-yellow. Of the metal ions investigated, only Al3+ caused any increase in the fluorescence intensity of 1. All other metal ions, including K(I), Na(I), Ag(I), Li(I), Zn(II), Co(II) and Hg(II), showed a negligible fluorescence response, while Cu(II) and Fe(III) significantly decreased the fluorescence intensity. Therefore, system 1 is a promising colourimetric sensor for Al3+, and a fluorescence sensor for Cu2+ and Fe3+ ions. Computational analysis revealed that 1 is unionized in ethanol solution, while it becomes di-deprotonated to 12– upon the complexation with Al3+. This changes the electronic structure of 1 and leaves no acidic hydrogen atoms to allow the ESIPT process. On the other hand, the presence of monovalent metal cations induces only mono-deprotonation to 1–, which turns out to be an insufficient electronic change to be spotted in the recorded spectra.
CT14 Intrinsic Charm Parton Distribution Functions from CTEQ-TEA Global Analysis
Creators: name: Hou, Tie-Jiun
name: Dulat, Sayipjamal
name: Gao, Jun
name: Guzzi, Marco
name: Huston, Joey
name: Nadolsky, Pavel
name: Schmidt, Carl
name: Winter, Jan
name: Xie, Keping
name: Yuan, C. -P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate the possibility of a (sizable) nonperturbative contribution to the charm parton distribution function (PDF) in a nucleon, theoretical issues arising in its interpretation, and its potential impact on LHC scattering processes. The "fitted charm" PDF obtained in various QCD analyses contains a process-dependent component that is partly traced to power-suppressed radiative contributions in DIS and is generally different at the LHC. We discuss separation of the universal component of the nonperturbative charm from the rest of the radiative contributions and estimate its magnitude in the CT14 global QCD analysis at the next-to-next-to leading order in the QCD coupling strength, including the latest experimental data from HERA and the Large Hadron Collider. Models for the nonperturbative charm PDF are examined as a function of the charm quark mass and other parameters. The prospects for testing these models in the associated production of a Z boson and a charm jet at the LHC are studied under realistic assumptions, including effects of the final-state parton showering.
description: 57 pages, 19 figures, and 3 tables
Passerina uniflora Linnaeus, 1753, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1753
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malvales
Thymelaeaceae
Passerina
Passerina uniflora

description: Passerina uniflora, spec. nov.
4. Passerina foliis linearibus oppositis, floribus terminalibus solitariis, ramis glabris.
 Thymelaea foliis triquetris cruciatim oppositis, flore sericeo. Burm. afr. 132. t.48. f.2.
 Thymelaea ramosa, linearibus foliis angustis, flore solitario. Burm. afr. 131. t.48. f.1.
 Habitat in Aethiopia . ♄
description: Published as part of Linnaeus, Carolus, 1753, Species plantarum: exhibentes plantas rite cognitas, ad genera relatas, cum differentiis specificis, nominibus trivialibus, synonymis selectis, locis natalibus, secundum systema sexuale digestas, Stockholm :Laurentius Salvius on page 560, DOI: 10.5281/zenodo.3931989
Additional file 1 of Association between initial intravenous fluid volume and the composite outcome of hemodialysis dependence at discharge or in-hospital mortality in inpatients with rhabdomyolysis
Creators: name: Yajima, Wataru
name: Aso, Shotaro
name: Matsui, Hiroki
name: Fushimi, Kiyohide
name: Yasunaga, Hideo
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 1. Figure S1. Forest plots of RDs of IVF ≥ 3500 mL/day for hemodialysis dependence at discharge in subgroups.
Combined transcatheter treatment of severe mitral regurgitation and secundum atrial septal defect in an inoperable patient: a case report
Creators: name: Barbieri, Fabian
name: Landmesser, Ulf
name: Kasner, Mario
name: Reinthaler, Markus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: Mitral regurgitation
subject: Atrial septal defect
subject: Atrial septal defect closure
subject: Mitral valve repair
subject: MitraClip
subject: Case report
subject: Transcatheter
subject: Transcatheter therapeutics
subject: Right heart failure
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Chronic mitral regurgitation (MR) is one of the most common valvular heart diseases and is associated with poor outcomes. Although other structural diseases are regularly seen in such patients, concomitant atrial septal defects (ASDs) remain a rarity in the elderly. Case summary: We report a case of an 82-year-old woman with progressive right-sided heart failure (HF) due to MR and an ASD of secundum type, despite optimal medical therapy. Combined transcatheter mitral valve repair (MVR) by utilizing a separate transseptal puncture and ASD closure was performed resulting in amelioration of symptoms. Discussion: Procedural planning for simultaneous transcatheter therapies of coupled structural heart disease entities remains complex. Our case illustrates feasibility of percutaneous edge-to-edge MVR and consecutive closure of a large secundum ASD. Different options of accessing the left atrium should be discussed on an individual basis, while additional ASD closure may be beneficial in terms of right ventricular function and symptoms of right HF.
Heart Rate Variability and Recurrent Stroke and Myocardial Infarction in Patients With Acute Mild to Moderate Stroke
Creators: name: Rennenberg, Regina Von
name: Krause, Thomas
name: Herm, Juliane
name: Hellwig, Simon
name: Scheitz, Jan F.
name: Endres, Matthias
name: Haeusler, Karl Georg
name: Nolte, Christian H.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: stroke
subject: heart rate variability
subject: functional outcome
subject: cardiovascular events
subject: heart and brain interaction
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objectives: In patients with acute ischemic stroke, reduced heart rate variability (HRV) may indicate poor outcome. We tested whether HRV in the acute phase of stroke is associated with higher rates of mortality, recurrent stroke, myocardial infarction (MI) or functional outcome. Materials and Methods: Patients with acute mild to moderate ischemic stroke without known atrial fibrillation were prospectively enrolled to the investigator-initiated Heart and Brain interfaces in Acute Ischemic Stroke (HEBRAS) study (NCT 02142413). HRV parameters were assessed during the in-hospital stay using a 10-min section of each patient's ECG recording at day- and nighttime, calculating time and frequency domain HRV parameters. Frequency of a combined endpoint of recurrent stroke, MI or death of any cause and the respective individual events were assessed 12 months after the index stroke. Patients' functional outcome was measured by the modified Rankin Scale (mRS) at 12 months. Results: We included 308 patients (37% female, median NIHSS = 2 on admission, median age 69 years). Complete follow-up was achieved in 286/308 (93%) patients. At 12 months, 32 (9.5%), 5 (1.7%) and 13 (3.7%) patients had suffered a recurrent stroke, MI or death, respectively. After adjustment for age, sex, stroke severity and vascular risk factors, there was no significant association between HRV and recurrent stroke, MI, death or the combined endpoint. We did not find a significant impact of HRV on a mRS ≥ 2 12 months after the index stroke. Conclusion: HRV did not predict recurrent vascular events in patients with acute mild to moderate ischemic stroke.
Findings and Graduation of Sarcoidosis-Related Uveitis: A Single-Center Study
Creators: name: Bonsen, Lynn S. Zur
name: Pohlmann, Dominika
name: Rübsam, Anne
name: Pleyer, Uwe
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: differential diagnosis
subject: IWOS criteria
subject: granulomatosis
subject: neurosarcoidosis
subject: ocular sarcoidosis
subject: uveitis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Ocular involvement is present in up to 79% of sarcoid patients. Uveitis is the main ocular manifestation and presents as a chronic intraocular inflammatory condition with potentially detrimental effects on visual acuity and quality of life. This retrospective study was conducted to explore the incidence and characteristics of ocular sarcoidosis in a single tertiary ophthalmology center. Medical records of 84 patients presenting between June 2007 and March 2021 were analyzed. Based on the "International Workshop on Ocular Sarcoidosis" (IWOS) criteria, ocular sarcoidosis was determined as: definite (n = 24; 28.6%), presumed (n = 33; 39.3%), probable (n = 10; 11.9%), and indefinite (n = 17; 20.2%) in our study population. In 43.9% of the definite and presumed cases, the eye was primarily affected. In addition to specific ocular findings, the diagnosis was supported by biopsy (28.6%) and chest x-ray or computer tomography (66.7%). Moreover, an increased soluble interleukin-2 receptor (sIL-2R) expression (76.2%), elevated angiotensin-converting enzyme (ACE) levels (34.8%), and lymphocytopenia (35.1%) were valuable laboratory findings. Co-affected organs were lungs (60.7%), skin (15.5%), and central nervous system (8.3%). Our findings support the prominent role of the eye in the early detection of sarcoidosis. In addition to the IWOS criteria, sIL-2R, in particular, was shown to be relevant in establishing the diagnosis.
MOESM2 of Effective editing for lysophosphatidic acid acyltransferase 2/5 in allotetraploid rapeseed (Brassica napus L.) using CRISPR-Cas9 system
Creators: name: Zhang, Kai
name: Nie, Liluo
name: Cheng, Qiqi
name: Yin, Yongtai
name: Chen, Kang
name: Qi, Fuyu
name: Zou, Dashan
name: Liu, Haohao
name: Zhao, Weiguo
name: Wang, Baoshan
name: Li, Maoteng
Publisher: name: figshare
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Sequence alignment of the four BnLPAT5 homologous genes.
Additional file 2 of Association between initial intravenous fluid volume and the composite outcome of hemodialysis dependence at discharge or in-hospital mortality in inpatients with rhabdomyolysis
Creators: name: Yajima, Wataru
name: Aso, Shotaro
name: Matsui, Hiroki
name: Fushimi, Kiyohide
name: Yasunaga, Hideo
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Computational Biology

description: Supplementary Material 2. Figure S2. Forest plots of RDs of IVF ≥ 3500 mL/day for in-hospital death in subgroups.
Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
Creators: name: Krause, Nicolas
name: Mengwasser, Jörg
name: Phithak, Elpida
name: Beato, Francisca
name: Appis, Marc
name: Milford, Edgar Louis
name: Pratschke, Johan
name: Sauer, Igor
name: Kuehl, Anja
name: Vogel, Arndt
name: Goodyear, Michael
name: Hammerich, Linda
name: Tacke, Frank
name: Haas, Johanna Faith
name: Müller, Tobias
name: Utku, Nalan
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: T regulatory cells
subject: IR1 cells
subject: TIRC7
subject: autoimmunity
subject: immune regulatory Cell 1
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: A subset of T regulatory cells (Tregs), identified by TIRC7 (T cell immune response cDNA 7) expression is designated as Immune Regulatory 1 Cells (IR1 cells). TIRC7 is an immune checkpoint inhibitor, co-localized with the T- cell receptor, HLA-DR and CTLA-4 during T-cell activation, which delivers regulatory signals via binding to its ligand, HLA-DR α2 domain. IR1 cells express FOXP3, and multiple other markers associated with immune suppression. They constitute as much as 10% of Tregs. IR1 cells strongly inhibit proliferation in mixed lymphocyte reactions, where they express high levels of IL-10. Ex vivo expansion of Tregs over 2 weeks in the presence of an agonist TIRC7 antibody disproportionately expands the IR1 Treg subset, while maintaining high expression of suppressive markers including CD39, IL-10, LAP and GARP. Ex vivo expanded IR1 cells are a potent, homogeneous, stable set of suppressor Tregs with the potential to modulate immune dysregulation. The characteristics of IR1 cells suggest a therapeutic advantage over polyclonal Tregs for therapeutic interventions. Early restoration of immune homeostasis using IR1 cells has the potential to fundamentally alter the natural history of conditions characterized by abnormalities in the T regulatory cell compartment.
$η_{Q}$ meson photoproduction in ultrarelativistic heavy ion collisions
Creators: name: Yu, Gong-Ming
name: Zhao, Gao-Gao
name: Bai, Zhen
name: Cai, Yan-Bing
name: Yang, Hai-Tao
name: Wang, Jian-Song
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The transverse momentum distributions for inclusive $η_{c,b}$ meson described by gluon-gluon interactions from photoproduction processes in relativistic heavy ion collisions are calculated. We considered the color singlet (CS) and color octet (CO) components with the framework of non-relativistic Quantum Chromodynamics (NRQCD) into the production of heavy quarkonium. The phenomenological values of the matrix elements for the color-singlet and color-octet components give the main contribution to the production of heavy quarkonium from the gluon-gluon interaction caused by the emission of additional gluon in the initial state. The numerical results indicate that the contribution of photoproduction processes cannot be negligible for mid-rapidity in p-p and Pb-Pb collisions at the Large Hadron Collider (LHC) energies.
description: 11 pages, 2 figures
Synergies of Multiple Zeitgebers Tune Entrainment
Creators: name: Grabe, Saskia
name: Mahammadov, Elmir
name: Olmo, Marta Del
name: Herzel, Hanspeter
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: circadian clock
subject: synchronisation
subject: mathematical model
subject: zeitgeber synergy
subject: resonance
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Circadian rhythms are biological rhythms with a period close to 24 h. They become entrained to the Earth’s solar day via different periodic cues, so-called zeitgebers. The entrainment of circadian rhythms to a single zeitgeber was investigated in many mathematical clock models of different levels of complexity, ranging from the Poincaré oscillator and the Goodwin model to biologically more detailed models of multiple transcriptional translational feedback loops. However, circadian rhythms are exposed to multiple coexisting zeitgebers in nature. Therefore, we study synergistic effects of two coexisting zeitgebers on different components of the circadian clock. We investigate the induction of period genes by light together with modulations of nuclear receptor activities by drugs and metabolism. Our results show that the entrainment of a circadian rhythm to two coexisting zeitgebers depends strongly on the phase difference between the two zeitgebers. Synergistic interactions of zeitgebers can strengthen diurnal rhythms to reduce detrimental effects of shift-work and jet lag. Medical treatment strategies which aim for stable circadian rhythms should consider interactions of multiple zeitgebers.
Boundary layer of elastic turbulence
Creators: name: Belan, S.
name: Chernykh, A.
name: Lebedev, V.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We investigate theoretically the near-wall region in elastic turbulence of a dilute polymer solution in the limit of large Weissenberg number. As it was established experimentally, elastic turbulence possesses a boundary layer where the fluid velocity field can be approximated by a steady shear flow with relatively small fluctuations on the top of it. Assuming that at the bottom of the boundary layer the dissolved polymers can be considered as passive objects, we examine analytically and numerically statistics of the polymer conformation, which is highly nonuniform in the wall-normal direction. Next, imposing the condition that the passive regime terminates at the border of the boundary layer, we obtain an estimate for the ratio of the mean flow to the magnitude of flow fluctuations. This ratio is determined by the polymer concentration, the radius of gyration of polymers and their length in the fully extended state. The results of our asymptotic analysis reproduce the qualitative features of elastic turbulence at finite Weissenberg numbers.
description: 11 pages, 2 figures
The impact of the Tokyo Metropolitan Emissions Trading Scheme on reducing greenhouse gas emissions: findings from a facility-based study
Creators: name: Wakabayashi, Masayo
name: Kimura, Osamu
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy

description: This paper provides a detailed analysis of the Tokyo Metropolitan Emissions Trading Scheme (Tokyo ETS), Japan’s first emissions trading scheme with mandatory cap initiated by the government of Tokyo. Unlike trading schemes in other countries, the Tokyo ETS covers indirect emissions from the commercial sector. It is well known that a variety of market barriers impede full realization of energy efficiency opportunities, especially in the commercial sector. Experiences with the Tokyo ETS should therefore provide important lessons for the design of climate change mitigation policies, especially when targeting the commercial sector. The emissions from covered entities have been drastically reduced from those at the scheme’s outset, with an average 14% reduction as of the end of the first commitment period of five years (2010–2014) compared with 2009 levels. This paper shows that the Tokyo ETS alone did not cause these reductions; there were other drivers. Among them, the energy savings triggered by the Great East Japan Earthquake in 2011 were crucial. The contribution of credit trading, in contrast, was limited since most of the covered entities reduced emissions by themselves. Through an investigation of official reports, an assessment of the emissions data from the covered entities compared to those of uncovered entities and in-depth interviews with firms covered by the scheme, this paper confirms that the main drivers of emissions reductions by covered entities were separate from the ETS. In fact, the advisory aspect of the scheme seems to be much more important in encouraging energy-saving actions. Key policy insightsMost of the observed emission reductions were not caused by the Tokyo ETS alone.An advisory instrument was crucial to the effectiveness of the Tokyo ETS.The experience of the Tokyo ETS suggests that making full use of the advantages of emissions trading is difficult in the case of the commercial sector.Price signals have not provided a stimulus to climate change mitigation actions, which implies that establishing a cap to yield effective carbon prices poses a challenge. Most of the observed emission reductions were not caused by the Tokyo ETS alone. An advisory instrument was crucial to the effectiveness of the Tokyo ETS. The experience of the Tokyo ETS suggests that making full use of the advantages of emissions trading is difficult in the case of the commercial sector. Price signals have not provided a stimulus to climate change mitigation actions, which implies that establishing a cap to yield effective carbon prices poses a challenge.