cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Spatial and Temporal Patterns of Genetic Variation in Scarlet Macaws: Implications for Population Management in La Selva Maya, Central America
Creators: Schmidt, Kari
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Wildlife conservation
subject: Genetics
subject: FOS: Biological sciences

description: Advances in technology and molecular methodologies now provide an unprecedented view into the complex realm of natural populations by elucidating the degree and distribution of genetic variation, historical and contemporary processes driving differentiation, and individual behavior patterns. These critical biological parameters create a framework to enhance wildlife management initiatives, as illustrated here through the implementation of a model approach for the systematic genetic assessment of a group of scarlet macaws Ara macao under threat in La Selva Maya, a tri-national system of protected areas in Mexico, Guatemala, and Belize. A total of 2172 base pairs across four mitochondrial data partitions were employed to test the current hypothesis of subspecific diversification. Phylogenetic reconstruction uncovered two phylogeographic units exhibiting distinct and complex evolutionary histories, emphasizing the importance of Central American populations to intraspecific diversity. Focusing on A. m. cyanoptera, mitochondrial control region sequences of 850 base pairs were examined within a hierarchical context to investigate patterns of genetic substructure at varying spatial scales and extent of molecular variation, including potential temporal shifts in response to anthropogenic pressures. Population-level statistical tests detected evidence of recently restricted gene flow among nest sites in La Selva Maya, a stark contrast to the historical state of panmixia across the region; although overall levels of genetic variation remain high, a decrease in diversity was noted among modern samples originating in the Chiquibul Forest Reserve, Belize. Multilocus genotypes based on eight microsatellite markers were combined with haplotypic data to evaluate whether focal nest sites in the Maya Biosphere Reserve, Guatemala represent distinct genetic clusters. Results from population genetic analyses argue against the presence of site fidelity at fine geographic scales. Examination of pairwise relative relatedness indices supports the observation of genetic connectivity across local breeding areas, while also revealing important insights into recent demographic trends, movement patterns, and breeding behaviors. In summary, this work demonstrates the continuity of biological and ecological influences across individual, local, regional, and continental scales, thus creating an empirical framework to refine population management goals and prioritize mitigation strategies in order to maximize conservation outcomes and foster long-term survival of wild scarlet macaws in La Selva Maya.
title: Eine Klasse von Ellipsenflächen : Herrn Heinz Kunle zum 50. Geburtstag gewidmet
Creators: name: Vogel, Walter
Publisher: name: Goltze
Year: 1980
Subjects: subject: Brunsvicensien der Universitätsbibliothek Braunschweig
subject: Abhandlungen der BWG
subject: 510

description: Eine Ellipsenfläche ist eine von einer einparametrigen Schar von Ellipsen erzeugte Fläche im dreidimensionalen euklidischen Raum. Die hier betrachtete Klasse besteht aus den Ellipsenflächen mit den Eigenschaften: 1. die Fläche ist ein Teil einer C4-Eifläche), d.h. einer geschlossenen Fläche der Klasse C4 mit positiver Gaußscher Krümmung K>0, 2. die erzeugenden Ellipsen sind kongruente Ellipsen, im Sonderfall kongruente Kreise, und 3. die Fläche ist nach W. Degen vom hyperbolischen Typ, d. h. jede Erzeugende der von den Ellipsenebenen eingehüllten Torse schneidet die zugehörige erzeugende Ellipse in zwei (reellen) Punkten. Wir nennen diese Flächen kurz K-Ellipsenflächen.
In der vorliegenden Note werden lokale Eigenschaften dieser Flächen untersucht. Nach Aufstellen der Grundgleichungen wird bewiesen, daß jede K-Ellipsenfläche ein Stück einer Quadrik ist. Es folgen Beispiele, die zeigen, daß eine Ellipsenfläche keine Quadrik sein muß, wenn eine der genannten Eigenschaften nicht erfüllt ist. Schließlich wird noch untersucht, unter welchen zusätzlichen Bedingungen eine K-Ellipsenfläche eine Drehquadrik ist.
In einer späteren Note werden kinematische und globale Fragen der K-Ellipsenflächen behandelt werden.
A inovação em educação como tema de interesse no jornal "Traço de União" da escola de educadoras de infancia ''Maria Ulrich" (Lisboa-Portugal, 1966-1973)
Creators: name: Figueiredo Pinto, Rooney
name: Gomes Ferreira, António
name: Mota, Luís
Publisher: name: Zenodo
Year: 2021
Subjects: História da Educação
Traço de União
História da Imprensa Educativa
Escola de Educadoras de Infância "Maria Ulrich"
Inovação
Educação

description: O jornal "Traço de União" foi publicado pela Escola de Educadoras de Infância "Maria Ulrich", em Lisboa, no período de 1966 a 1973. Com uma periodicidade eventual, formato próximo ao tabloide, ntre 8 e 12 páginas impressas com até três colunas de texto por página, explorava temas relacionados à criança e à formação moral e pedagógica das educadoras de infância, a missão social dos especialistas em pedagogia infantil e os jardins de infância. Em alguns exemplares também eram reproduzidos artigos da revista La Femmee et la, Vie, le Monde, bem como excertos de livros. Como parte de uma investigação em desenvolvimento, este trabalho tem por objetivo apontar algumas reflexões sobre a inovação em educação como tema de interesse no jornal ''Traço de União". Adotando uma metodologia qualitativa, com análise dos conteúdos dos jornais (1966-1973), propomos reflexões às seguintes perguntas: Que conteúdos e objetivos eram privilegiados no jornal ''Traço de União"? Como enunciava a inovação e que autores e práticas eram apontadas como inovadoras? Qual a relevância do "Traço de União" no contexto português das educadoras de infância entre as décadas de 60 e 70 do século XX? A análise dos conteúdos permitiu verificar a distribuição dos textos e seus objetivos, constatando que os ''Testemunhos" assumiam o protagonismo no jornal, sendo predominantemente utilizados para transmitir impressões, partilhar informações atualizadas e práticas reconhecidas nos textos como inovadoras, como a educação pela arte, a Escola Nova e os KinderGartens. Destacam-se, sobretudo, os testemunhos sobre os Jardins-Escolas João de Deus as quais são referenciadas em associação com exemplos estrangeiros, particularmente da Bélgica (escolas de Decroly) e Itália (Casas Dei Bambini) bem como as referências a Pestalozzi, Blanche Harvaux, Marie-Aimée Niox-Chateau, os quais estão entre os autores citados ou cujos textos foram reproduzidos no jornal como incentivo à uma perspetiva vanguardista da educação. Embora seja um jornal com poucas edições e curta existência, o jornal ''Traço de União" apresenta possibilidades para diversas investigações no âmbito da imprensa pedagógica e espaço de partilha de conhecimentos e experiências inovadoras no contexto português do século XX. Ao utilizar os testemunhos como recurso de partilha, promove a categoria profissional de educadoras de infância, convoca à reflexão sobre as práticas pedagógicas de vanguarda em Portugal e na Europa, e posiciona-se como um jornal onde a inovação em educação é um tema de interesse.
The Klein-Gordon equation on the hyperboloidal anti-de Sitter Schwarzschild black hole
Creators: name: Fitz-Gibbon, Owain Salter
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we establish energy decay for solutions to the Klein-Gordon equation on the positive mass hyperboloidal anti-de Sitter Schwarzschild black hole, subject to Dirichlet, Neumann and Robin boundary conditions at infinity, for a range of the (negative) mass squared parameter. To do so we use vector field methods with a renormalised energy to avoid divergences that would otherwise appear in the energy integrals. For another region of the parameter space, we use the existence of negative energy solutions to demonstrate linear instability.
Averaging Inhomogeneous Cosmologies -- a Dialogue
Creators: name: Buchert, Thomas
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The averaging problem for inhomogeneous cosmologies is discussed in the form of a disputation between two cosmologists, one of them (RED) advocating the standard model, the other (GREEN) advancing some arguments against it. Technical explanations of these arguments as well as the conclusions of this debate are given by BLUE.
description: LaTeX 12 pages, two figures, uses paspconf.sty, psfig.sty. To appear in Proceedings 2nd SFB Workshop on Astro-particle physics, Ringberg 1996
MOESM4 of Spatial modeling, prediction and seasonal variation of malaria in northwest Ethiopia
Creators: name: Asefa Taddese
name: Adhanom Baraki
name: Kassahun Gelaye
Publisher: name: figshare
Year: 2019
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology

description: Additional file 4. Spatial autocorrelation based on feature locations and attribute values using the Global Moranâ s I statistic.
Marsdenia schimperi Decne.
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Marsdenia
Marsdenia schimperi

description: Marsdenia schimperi Decne.  —
Habit: Liana or shrub.
Habitat: LMWF, LMDF; 1 400–2 700 m. Distribution: I.
 Voucher: Nkunga Crater Lake, Alt. 1 900 m, 19 Jan. 2001, Luke et al. 7234 (EA).
References: Bussmann (1993, 1994), Bussmann & Beck (1995a, 1998), Agnew (2013).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 77, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Garçonne, but Make Her Flapper. Using American Femininity Models to Re-Fashion the Romanian 'Modern Girl'
Creators: name: Andras, Sonia
Publisher: name: Presa Universitară Clujeană
Year: 2023
Subjects: subject: Women
subject: Fashion
subject: Sex role
subject: Romania
subject: United States
subject: Nineteen twenties

description: This chapter examines the reception of the American 'flapper' model and how it was interpreted and translated into the interwar Romanian fashion and beauty discourse, into the 1920s model termed as the 'modern girl', as opposed to the 'new woman' of the 1930s. It follows the evolution of 1920s styles, including Jazz and Hollywood cultures, Jazz, specific fashions like Egyptomania, low-waist hems, short skirts, bobbed hair and striking makeup, alongside US social, economic and ideological concepts. This chapter explores how the Parisian dominance of culture, fashion and beauty was gradually overridden by American sartorial and aesthetic vernaculars, even if the garments and designs themselves still originated mainly from Paris. It thus follows the evolution of the 'modern girl' from the demure lady of yore towards the glamorous divas that would come to define Classic Hollywood. The 1920-1929 timeline covers the post-war crystallization of Greater Romania until the Great Depression, which brought about the demise of the 'modern girl' and the "Roaring Twenties". This chapter will use primary materials from published book and periodical sources, as well as items from my personal collection. Its methodology will be based on visual and textual discourse analysis, using fashion as the main connection between characters and contexts.
Automated Classification of Histopathology Images Using Transfer Learning
Creators: name: Talo, Muhammed
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: There is a strong need for automated systems to improve diagnostic quality and reduce the analysis time in histopathology image processing. Automated detection and classification of pathological tissue characteristics with computer-aided diagnostic systems are a critical step in the early diagnosis and treatment of diseases. Once a pathology image is scanned by a microscope and loaded onto a computer, it can be used for automated detection and classification of diseases. In this study, the DenseNet-161 and ResNet-50 pre-trained CNN models have been used to classify digital histopathology patches into the corresponding whole slide images via transfer learning technique. The proposed pre-trained models were tested on grayscale and color histopathology images. The DenseNet-161 pre-trained model achieved a classification accuracy of 97.89% using grayscale images and the ResNet-50 model obtained the accuracy of 98.87% for color images. The proposed pre-trained models outperform state-of-the-art methods in all performance metrics to classify digital pathology patches into 24 categories.
Logarithmic moments of characteristic polynomials of random matrices
Creators: name: Brezin, E.
name: Hikami, S.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In a recent article we have discussed the connections between averages of powers of Riemann's $ζ$-function on the critical line, and averages of characteristic polynomials of random matrices. The result for random matrices was shown to be universal, i.e. independent of the specific probability distribution, and the results were derived for arbitrary moments. This allows one to extend the previous results to logarithmic moments, for which we derive the explicit universal expressions in random matrix theory. We then compare these results to various results and conjectures for $ζ$-functions, and the correspondence is again striking.
description: 10 pages, latex
title: Erweiterung des Satzes von Holditch für geschlossene Raumkurven : Herrn Prof. Dr. Walter Wunderlich zum 70. Geburtstag gewidmet
Creators: name: Müller, Hans
Publisher: name: Goltze
Year: 1980
Subjects: subject: Brunsvicensien der Universitätsbibliothek Braunschweig
subject: Abhandlungen der BWG
subject: 510

description: Es wird gezeigt, daß sich der klassische Satz von Holditch in der Weise auf Raumkurven übertragen läßt, daß er bei Einführung einer geeigneten Metrik für die Normalprojektion auf eine beliebige Ebene des Raumes gilt.
Additional file 3: of Identification of plasma microRNA expression changes in multiple system atrophy and Parkinsonâ s disease
Creators: name: Uwatoko, Hisashi
name: Hama, Yuka
name: Iwata, Ikuko
name: Shirai, Shinichi
name: Matsushima, Masaaki
name: Yabe, Ichiro
name: Utsumi, Jun
name: Sasaki, Hidenao
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Table S3. Top 15 statistically significant GO processes relevant to the top 50 predicted target genes of hsa-miR-19b-3p. (DOCX 18 kb)
Essays on investment in the hotel industry
Creators: name: Kuo, Fang-Chang
name: 0000-0002-1079-0937
Publisher: name: The University of Texas at Austin
Year: 2019
Subjects: Competition
Investment
Reputation
Online ratings
Dynamic

description: This dissertation studies issues on investments in the hotel industry. The first two chapters empirically investigate the relationship between investment and competition. My study shows that competition negatively impacts firms' investment decisions. The third chapter focuses on the reputation effects on hotel investment, and shows that better online ratings are associated with lower investment expenditures. In the first chapter, I use data from Taiwanese hotel industry to investigate the relationship between competition and investment in a reduced-form analysis. Competition intensity is measured by the number of hotels in a market. Regression analysis indicates that investment is negatively correlated with the number of hotels. I then use a structural model of demand to recover unobserved demand shocks and control for future demand shocks in regression analysis. The results also show a negative relationship. The second chapter develops a dynamic model of investment and entry and conducts four counterfactual experiments to analyze competition policies and long-run equilibrium investments. Hotels make static pricing, and dynamic investment decisions in every period. Potential entrant could enter a market by comparing entry cost and value function of an incumbent. My counterfactual experiments show that competition effects from entry reduce the return from investment and weaken investment incentives. Reducing entry cost by 20% actually leads to 13% decrease in average investments, and thus average unobserved qualities decrease. Consumers still benefit from increased product variety and lower prices. The net changes in consumer surplus are positive. However, ignoring the negative competition effects on investments will overestimate consumer surplus under such a policy. In my third chapter, I investigate the impact of reputation on investment in Taiwanese hotel industry. Specifically, how do reputation affect endogenous product characteristics, quality, through investment decisions? The empirical strategy consists of a reduced-form analysis. I supplement the hotel financial performance data with with a panel of consumer ratings from major review platforms: TripAdvisor, Agoda, Expedia, and Bookings.com. The regression results indicate that hotels with better online ratings tend to invest less or less frequently. Controlling for past investments also show similar results
Pyro-electrohydrodynamic jet printing of an organic dye in diluted solutions for detecting low abundant molecules
Creators: name: Itri, Simona
name: Rega, Romina
name: Giudice, Danila Del
name: Mugnano, Martina
name: Tkachenko, Volodymyr
name: Kokkonen, Annukka
name: Aikio, Sanna
name: Uusitalo, Sanna
name: Ferraro, Pietro
name: Grilli, Simonetta
Publisher: name: Zenodo
Year: 2021
Subjects: Pyro-electrohydrodynamic jet printing

description: Pyro-electrohydrodynamic jet printing of an organic dye in diluted solutions for detecting low abundant molecules
Expected value of the one-dimensional Earth Mover's Distance
Creators: name: Bourn, Rebecca
name: Willenbring, Jeb F.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05E40, 62H30

description: From a combinatorial point of view, we consider the Earth Mover's Distance (EMD) associated with a metric measure space. The specific case considered is deceptively simple: Let the finite set [n] = {1,...,n} be regarded as a metric space by restricting the usual Euclidean distance on the real numbers. The EMD is defined on ordered pairs of probability distributions on [n]. We provide an easy method to compute a generating function encoding the values of EMD in its coefficients, which is related to the Segre embedding from projective algebraic geometry. As an application we use the generating function to compute the expected value of EMD in this one-dimensional case. The EMD is then used in clustering analysis for a specific data set.
description: To appear in the Journal of Algebraic Statistics
Osburn repository siting : case history, Bunker Hill Mining and Metallurgical Complex Superfund Site cleanup
Creators: name: Vernon, Donald K.
name: Mork, Andy
Publisher: name: The University of British Columbia
Year: 2011

description: The location for the new Coeur d’Alene Basin Repository was selected based on a two-phased siting process. The first phase was to develop an inventory of potential candidate sites through research at the County assessor’s office and communication with realtors; local, state, and federal agencies; and the Coeur d’Alene Indian Tribe. A total of 94 candidate sites were carried forward to the second phase, which involved an initial screening exercise to winnow the 94 sites to a workable number for further assessment. During this phase, citizens’ input was incorporated into the repository siting process. To achieve this goal, two workshops were held to identify the important siting factors from the public’s perspective. The public input was distilled into a list of nine screening criteria. Performance scores/values from stakeholders were developed for every candidate site for each of the criteria. Based on citizen criteria ranking, the Osburn Tailings Impoundment was recommended for further evaluation. [All papers were considered for technical and language appropriateness by the organizing committee.]
Learning To Follow Directions in Street View
Creators: name: Hermann, Karl Moritz
name: Malinowski, Mateusz
name: Mirowski, Piotr
name: Banki-Horvath, Andras
name: Anderson, Keith
name: Hadsell, Raia
Publisher: name: arXiv
Year: 2019
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Navigating and understanding the real world remains a key challenge in machine learning and inspires a great variety of research in areas such as language grounding, planning, navigation and computer vision. We propose an instruction-following task that requires all of the above, and which combines the practicality of simulated environments with the challenges of ambiguous, noisy real world data. StreetNav is built on top of Google Street View and provides visually accurate environments representing real places. Agents are given driving instructions which they must learn to interpret in order to successfully navigate in this environment. Since humans equipped with driving instructions can readily navigate in previously unseen cities, we set a high bar and test our trained agents for similar cognitive capabilities. Although deep reinforcement learning (RL) methods are frequently evaluated only on data that closely follow the training distribution, our dataset extends to multiple cities and has a clean train/test separation. This allows for thorough testing of generalisation ability. This paper presents the StreetNav environment and tasks, models that establish strong baselines, and extensive analysis of the task and the trained agents.
Supplementary tables and figure from Traffic noise exposure impacts song production in wild male field crickets (Gryllus bimaculatus) under predator and intrasexual competition contexts
Creators: name: Gallego-Abenza, Mario
name: Wheatcroft, David
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 310901
subject: Animal behaviour

description: Summary of model results for Baseline ICI, Baseline pulses per chirp, Latency to resume calling, Delta pulses per chirp, and likelihood of having a calling neighbour within five meters.
Erasure
Creators: name: Curry, Aaron Marshall Neihana
name: 0000-0002-2385-2981
Publisher: name: The University of Texas at Austin
Year: 2019
Subjects: Theatre
Design
Lighting
Perception
Lighting design
Lighting technology
Color
Human eyesight
Spectator space perception
Lighting effect on space perception
Colored lighting effect on space perception

description: In the visual and performing arts, light is widely applied as a tool with which artists and designers illuminate and modify space. Utilizing various techniques and qualities such as color and angle, and various lighting fixtures, lighting designers are able to influence how an audience perceives space to the benefit of the story being told. In Erasure, I aim to explore how lighting technology, color, and human eyesight interact in an attempt to alter a spectator’s perception of space. This thesis primarily focuses on how progressions through various wavelengths of visible light reflected in a constructed white room affect the perception of the space’s depth and the confines established by its boundaries. I also explore how successful varying wavelengths (colors) of light are in the erasing of line and edge, creating within the white room a seemingly vast expanse of color. In this investigation, I explore the process of researching color, light, and human vision, the construction and design of the performance space, and the resulting impact colored light has on spatial perception and what must be considered when attempting to apply a similar concept to larger live performances
Nonclassical Kinetics in Constrained Geometries: Initial Distribution Effects
Creators: name: Lindenberg, K.
name: Romero, A. H.
name: Sancho, J. M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We present a detailed study of the effects of the initial distribution on the kinetic evolution of the irreversible reaction A+B -> 0 in one dimension. Our analytic as well as numerical work is based on a reaction-diffusion model of this reaction. We focus on the role of initial density fluctuations in the creation of the macroscopic patterns that lead to the well-known kinetic anomalies in this system. In particular, we discuss the role of the long wavelength components of the initial fluctuations in determining the long-time behavior of the system. We note that the frequently studied random initial distribution is but one of a variety of possible distributions leading to interesting anomalous behavior. Our discussion includes an initial distribution with correlated A-B pairs and one in which the initial distribution forms a fractal pattern. The former is an example of a distribution whose long wavelength components are suppressed, while the latter exemplifies one whose long wavelength components are enhanced, relative to those of the random distribution.
description: To appear in International Journal of Bifurcation and Chaos Vol. 8 No. 5
title: Theodor Kristen
Creators: name: Kordina, Karl
Publisher: name: Goltze
Year: 1980
Subjects: subject: Brunsvicensien der Universitätsbibliothek Braunschweig
subject: Abhandlungen der BWG
subject: 902

description: Nachruf der Braunschweigischen Wissenschaftlichen Gesellschaft, vorgetragen in der Plenarversammlung am 14.3.1980
Spatial and genomic analysis of the glioblastoma tumor microenvironment
Creators: Chen, Andrew
Publisher: name: Columbia University
Year: 2020
Subjects: subject: Biology
subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Glioblastoma multiforme
subject: Brain--Cancer--Research
subject: Cancer--Immunotherapy--Evaluation
subject: Macrophages--Research

description: Glioblastoma (GBM) is an aggressive brain cancer with devastating outcomes and few effective treatments. Although immunotherapy has shown promise in treating a variety of cancers, it is still unclear if and how it can be effectively used in GBM. Elucidating this will require a better understanding of the mechanistic role of immune cells and their interactions in the GBM tumor microenvironment. This thesis utilizes recent technological developments in cancer genomics and imaging to study the mechanisms underlying immunotherapy and the tumor microenvironment. First, we will provide background on our current understanding of GBM, its immune microenvironment, as well as modern sequencing and imaging methods. Second, we will present a longitudinal study of GBM patients before and after treatment with PD-1 immunotherapy. Only a small fraction of GBM patients respond to this type of therapy, so we perform genomic, transcriptomic, and spatial analyses to compare the molecular features of these rare responders versus non-responders. We show that clinical response to PD-1 immunotherapy in GBM is associated with specific molecular alterations and immune infiltration profiles that reflect the tumor’s clonal evolution during treatment. The most common infiltrating immune cells in GBM are macrophages, which are implicated in a wide variety of pro-tumor and anti-tumor roles. We then focus on this specific immune population by analyzing single-cell expression data from GBM tumors. We identify a novel macrophage subpopulation characterized by expression of the scavenger receptor MARCO, which drives tumor progression in GBM and is altered over the course of PD-1 immunotherapy. Next, we demonstrate that the methods we have developed for GBM are applicable to understanding the tumor microenvironments of other cancers as well. We analyze a cohort of melanoma cases to show that transcriptomic and imaging features can be combined to create a biomarker that stratifies patients into different risk groups. Finally, while most of the image analysis described so far has utilized histopathology, we include two appendices where we demonstrate new ways to process and analyze Magnetic Resonance Imaging (MRI) in GBM.
New Neutron Star Equation of State with Quark-Hadron Crossover
Creators: name: Baym, Gordon
name: Furusawa, Shun
name: Hatsuda, Tetsuo
name: Kojo, Toru
name: Togashi, Hajime
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We present a much improved equation of state for neutron star matter, QHC19, with a smooth crossover from the hadronic regime at lower densities to the quark regime at higher densities. We now use the Togashi et al.~equation of state (Togashi:2017), a generalization of the Akmal-Pandharipande-Ravenhall equation of state of uniform nuclear matter, in the entire hadronic regime; the Togashi equation of state consistently describes non-uniform as well as uniform matter, and matter at beta equilibrium without the need for an interpolation between pure neutron and symmetric nuclear matter. We describe the quark matter regime at higher densities with the Nambu--Jona--Lasinio model, now identifying tight constraints on the phenomenological universal vector repulsion between quarks and the pairing interaction between quarks arising from the requirements of thermodynamic stability and causal propagation of sound. The resultant neutron star properties agree very well with the inferences of the LIGO/Virgo collaboration, from GW170817, of the pressure vs. baryon density, neutron star radii, and tidal deformabilities. The maximum neutron star mass allowed by QHC19 is 2.35 $M_\odot$, consistent with all neutron star mass determinations.
description: 8 pages, 11 figures; v3) published version, appendix was added
MOESM3 of Spatial modeling, prediction and seasonal variation of malaria in northwest Ethiopia
Creators: name: Asefa Taddese
name: Adhanom Baraki
name: Kassahun Gelaye
Publisher: name: figshare
Year: 2019
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 3. Significant high rate Spatio-temporal malaria clusters in North Gondar Zone; northwest Ethiopia from 2014 to 2017.
title: Hermann Glockner
Creators: name: Boeder, Heribert
Publisher: name: Goltze
Year: 1980
Subjects: subject: Brunsvicensien der Universitätsbibliothek Braunschweig
subject: Abhandlungen der BWG
subject: 902

description: Nachruf der Braunschweigischen Wissenschaftlichen Gesellschaft, vorgetragen in der Plenarversammlung am 14.11.1979
Mondia whitei Skeels
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Mondia
Mondia whitei

description: Mondia whitei (Hook.f.) Skeels  —
Habit: Liana.
Habitat: LMWF, BZ; up to 2 400 m. Distribution: II.
 Voucher: Near Kamweti Camp Site, Alt. 2 398 m, 31 Jan. 2015, SAJIT 003054 (HIB).
Reference: N/A.
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 77, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
title: Abfluß und Abflußschwankungen im periglazialen Milieu : Hydrologische Untersuchungen in Zentral-Island
Creators: name: Schunke, Ekkehard
Publisher: name: Goltze
Year: 1981
Subjects: subject: 550

description: Am Beispiel der Flüsse Blanda und Vatnsdalsá in Zentral-Island werden das Abflußverhalten von periglazialen Flußsystemen mit und ohne Gletscheranschluß und seine Einbindung in den Wasserhaushalt untersucht, und zwar anhand langfristiger Abflußmessungen seit 1949. Gemeinsames Kennzeichen des Abflußverhaltens beider Flußsysteme sind die hohen Abflußfaktoren von 0,83 bzw. 0,78 sowie der große Einfluß der frühsommerlichen Schneeschmelze. Der Wasserhaushalt beider Flußsysteme weist einen markanten Jahresgang des Vorrates auf, wobei das Vorratsmaximum im April besteht. Die jährliche Abflußspende und Abflußhöhe der Vatnsdalsá (ohne direkten Gletscheranschluß) erreichen im Mittel nur 76% der Werte der Blanda (mit direktem Gletscheranschluß). Das montan-nivale Abflußregime der Vatnsdalsá hat eine Abflußspitze im April/Mai, das niveo-glaziale Regime der Blanda hingegen zwei Abflußspitzen im April/Mai und im Juli/August. Die jährliche Abflußmenge variiert in Abhängigkeit von der Veränderung der klimatischen Parameter. Dabei entspricht ein deutlicher Rückgang der Abflußmengen in den 60er bis 70er Jahren dieses Jahrhunderts einer markanten Abnahme der Wärmesumme. Niederschlagsveränderungen beeinflussen zwar den Abfluß der Vatnsdalsá, kaum hingegen denjenigen der Blanda.
description: The rivers Blanda and Vatnsdalsá in Central Iceland are taken as examples for a study of the runoff behaviour of periglacial river systems with and without connection to glaciers. The interrelation between the runoff and the other elements of the water budget is investigated. For these purposes, long-term discharge measurements starting in 1949 are available. Characteristic features of the runoff behaviour of both river basins are the high runoff coefficients of 0.83 and 0.78 respectively and the determining influence of the foresummer snow-break. The water budget of either drainage basin shows a marked annual course of the water storage, the maximum reservoir contents existing in April. The mean annual runoff of the Vatnsdalsaá area (without direct connection to a glacier) only anmounts to 76% of the value for the Blanda area (possessing a direct connection to glaciers). Vatnsdalsá which follows a nival mountain runoff regime has its discharge peak in April/May, whereas Blanda, which follows a niveo-glacial regime, shows two peaks in April/May and in July/ August. The annual discharge totals varies depending on changes of the climatic parameters. Lower discharge totals during the 1960ies and early 1970ies is in accordance with a drop in the degree-days above 0°C. The long-term discharge of the Vatnsdalsá is clearly influenced by the variations of the precipitation, that of the Blanda only to a small extent.
The End of the Age Problem, And The Case For A Cosmological Constant Revisited
Creators: name: Krauss, Lawrence M.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The lower limit on the age of the universe derived from globular cluster dating techniques, which previously strongly motivated a non-zero cosmological constant, has now been dramatically reduced, allowing consistency for a flat matter dominated universe with a Hubble Constant, $H_0 \le 66 km s^{-1} Mpc^{-1}$. The case for an open universe versus a flat universe with non-zero cosmological constant is reanalyzed in this context, incorporating not only the new age data, but also updates on baryon abundance constraints, and large scale structure arguments. For the first time, the allowed parameter space for the density of non-relativistic matter appears larger for an open universe than for a flat universe with cosmological constant, while a flat universe with zero cosmological constant remains strongly disfavored. Several other preliminary observations suggest a non-zero cosmological constant, but a definitive determination awaits refined measurements of $q_0$, and small scale anisotropies of the Cosmic Microwave background. I argue that fundamental theoretical arguments favor a non-zero cosmological constant over an open universe. However, if either case is confirmed, the challenges posed for fundamental particle physics will be great.
description: 15 pages, Latex, including 2 eps figs, submitted to Science
Quantifying dimensionality: Bayesian cosmological model complexities
Creators: name: Handley, Will
name: Lemos, Pablo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We demonstrate a measure for the effective number of parameters constrained by a posterior distribution in the context of cosmology. In the same way that the mean of the Shannon information (i.e. the Kullback-Leibler divergence) provides a measure of the strength of constraint between prior and posterior, we show that the variance of the Shannon information gives a measure of dimensionality of constraint. We examine this quantity in a cosmological context, applying it to likelihoods derived from Cosmic Microwave Background, large scale structure and supernovae data. We show that this measure of Bayesian model dimensionality compares favourably both analytically and numerically in a cosmological context with the existing measure of model complexity used in the literature.
description: 14 pages, 9 figures. v2: updates post peer-review. v3: typographical correction to equation 35
Study Materials from Does promising facilitate children’s delay of gratification in interdependent contexts?
Creators: name: Koomen, Rebecca
name: Waddington, Owen
name: Goncalves, Leonor Santana Miranda
name: Koymen, Bahar
name: Jensen, Keith
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 529999
subject: Other psychology not elsewhere classified

description: Materials associated with the reproducibility of the study
Additional file 2: of Identification of plasma microRNA expression changes in multiple system atrophy and Parkinsonâ s disease
Creators: name: Uwatoko, Hisashi
name: Hama, Yuka
name: Iwata, Ikuko
name: Shirai, Shinichi
name: Matsushima, Masaaki
name: Yabe, Ichiro
name: Utsumi, Jun
name: Sasaki, Hidenao
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Table S2. Top 50 predicted target genes for each miRNA using miRmap. (DOCX 22 kb)
Pachycarpus concolor subsp. rhinophyllus Goyder
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Pachycarpus
Pachycarpus concolor
Pachycarpus concolor e.mey. subsp. rhinophyllus (k.schum.) goyder

description: Pachycarpus concolor E.Mey. subsp. rhinophyllus (K.Schum.) Goyder  —
Habit: Herb.
Habitat: LMDF; 1 400– 2 100 m. Distribution: IIIb.
Voucher: N/A.
Reference: Blundell (1987).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 77, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Athalia cornubiae Benson 1931
Creators: name: Taeger, Andreas
name: París, Mercedes
name: Nieves-Aldrey, Jose Luis
Publisher: name: Zenodo
Year: 2014
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Athalia
Athalia cornubiae

description: Athalia cornubiae Benson, 1931
A valid species, Athalia cornubiae Benson, 1931
Types. Athalia (Athalia) cornubiae Benson, 1931: 110. Holotype ♀, England, Cornwall, Looe (BMNH, not examined). Paratypes from France, Italy, and Spain. Paratypes in MNCN: 1 ♀ from Covadonga (MNCN _ Ent 82338), 1♀ from Villaverde (MNCN _ Ent 82339) both MNCN Cat. Tipos Nº 2267.
description: Published as part of Taeger, Andreas, París, Mercedes & Nieves-Aldrey, Jose Luis, 2014, The type specimens of sawflies (Hymenoptera: Symphyta) of the Museo Nacional de Ciencias Naturales, Madrid, pp. 103-138 in Zootaxa 3790 (1) on page 115, DOI: 10.11646/zootaxa.3790.1.5, http://zenodo.org/record/4914035
Magnetic Faraday-Instability
Creators: name: Mahr, Thomas
name: Rehberg, Ingo
Publisher: name: arXiv
Year: 1998
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: In a magnetic fluid parametrically driven surface waves can be excited by an external oscillating magnetic field. A static magnetic field changes the restoring forces and damping coefficients of the various surface waves. This property enables the excitation of both subharmonic and harmonic responses of the standing waves.
description: to be published in Europhysics Letters
Cynanchum viminale subsp. suberosum Goyder
Creators: name: Zhou, Ya-Dong
name: Mwachala, Geoffrey
name: Hu, Guang-Wan
name: Wang, Qing-Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Cynanchum
Cynanchum viminale
Cynanchum viminale (l.) l. subsp. suberosum (meve & liede) goyder

description: Cynanchum viminale (L.) L. subsp. suberosum (Meve & Liede) Goyder  —
Habit: Herb.
Habitat: LMDF; up to 2 100 m. Distribution: II.
Voucher: N/A.
 Reference: Fries et al. (1924a).
description: Published as part of Zhou, Ya-Dong, Mwachala, Geoffrey, Hu, Guang-Wan & Wang, Qing-Feng, 2022, Annotated checklist of the vascular plants of Mount Kenya, East Africa, pp. 1-108 in Phytotaxa 546 (1) on page 76, DOI: 10.11646/phytotaxa.546.1.1, http://zenodo.org/record/6550464
Twists and The Electronic Structure of Graphitic Materials
Creators: name: Cea, Tommaso
name: Walet, Niels R.
name: Guinea, Francisco
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We analyze the effect of twists on the electronic structure of configurations of infinite stacks of graphene layers. We focus on three different cases: an infinite stack where each layer is rotated with respect to the previous one by a fixed angle, two pieces of semi-infinite graphite rotated with respect to each other, and finally a single layer of graphene rotated with respect to a graphite surface. In all three cases we find a rich structure, with sharp resonances and flat bands for small twist angles. The method used can be easily generalized to more complex arrangements and stacking sequences.
description: 18 pages, 14 figures
Spatial regulation of protein function in cell division and midbody assembly
Creators: Hirsch, Sophia Madeleine
Publisher: name: Columbia University
Year: 2021
Subjects: subject: Cytology
subject: Genetics
subject: FOS: Biological sciences
subject: Cytokinesis
subject: Cell division
subject: Spindle (Cell division)
subject: Caenorhabditis elegans--Genetics
subject: Nematodes--Genetics

description: Cytokinesis is the physical division of one cell into two driven by an actomyosin contractile ring and positioned by signals from microtubules. This process is highly regulated spatially and temporally to ensure accurate division into two daughter cells. Here, I present work that builds upon our understanding of cytokinesis, focusing on the spatial requirements for protein function during cell division and midbody assembly. In Chapter 1, I present an introduction to cytokinesis and the cell and molecular mechanisms that govern the process. In Chapter 2, I present work I contributed to on the use of Upconverting nanoparticles for co-alignment of visible and infrared light on a light microscope. In Chapter 3, I present work developing a new microscopy technology called FLIRT (Fast Local Infrared Thermogenetics) that uses infrared light to inactivate fast-acting temperature sensitive protein function with subcellular precision and validate its use to study cytokinesis and cell fate signaling in the nematode Caenorhabditis elegans. In Chapter 4, I improve upon FLIRT technology by increasing its precision and demonstrate its use in studying the spatial regulation of key cytokinesis proteins including the actomyosin cytoskeleton in contractile ring constriction. The central spindle is an array of antiparallel overlapping microtubules that forms between the separating chromosomes in anaphase and is thought to serve as a signaling hub for cytokinesis. The central spindle is thought to become compacted during contractile ring constriction to form the dense midbody at the end of cell division. In Chapter 5, I investigate the requirements for central spindle microtubules in assembling midbodies in the C. elegans one-cell embryo. I present evidence that the CENP-F-like protein HCP-1 plays a primary role relative to its paralog HCP-2 in assembling the central spindle, and that the midbody can form independently of central spindle assembly. In Chapter 6, I discuss future directions for my work on both technology development and the mechanisms of cytokinesis. Through this work, I develop new technologies and hypotheses for how cytokinesis is spatially regulated within a cell, adding new complexity to our understanding of cell division.
Properties of charmed and bottom hadrons in nuclear matter: A plausible study
Creators: name: Tsushima, K.
name: Khanna, F. C.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Changes in properties of heavy hadrons with a charm or a bottom quark are studied in nuclear matter. Effective masses (scalar potentials) for the hadrons are calculated using quark-meson coupling model. Our results also suggest that the heavy baryons containing a charm or a bottom quark will form charmed or bottom hypernuclei, which was first predicted in mid 70's. In addition a possibility of $B^-$-nuclear bound (atomic) states is briefly discussed.
description: Latex, 11 pages, 3 figures, text was expanded substantially, version to appear in Phys. Lett. B