cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Ð¡ÑÑÐ°ÑÐµÐ³Ð¸Ð¸ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð¼Ð°Ð»Ð¾Ð³Ð¾ Ð±Ð¸Ð·Ð½ÐµÑÐ° Ð² ÑÑÐµÑÐµ ÐºÑÐµÐ°ÑÐ¸Ð²Ð½ÑÑ Ð°Ð³ÐµÐ½ÑÑÑÐ² (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ SONDER buro)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Strategies of promotion of small business in the sphere of creative agencies (on the example of âSONDER buroâ)
Creators: name: ÐÐ²Ð°Ð½Ð¾Ð²Ð°, Ð¯Ð½Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ
ÐºÑÐµÐ°ÑÐ¸Ð²Ð½Ð¾Ðµ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð¾
digital-Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ
Ð¼Ð°Ð»ÑÐ¹ Ð±Ð¸Ð·Ð½ÐµÑ
promotion strategy
creative agency
digital tools
small business

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾Ð½ÑÑÐ¸Ñ ÐºÑÐµÐ°ÑÐ¸Ð²Ð½Ð¾Ðµ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð¾. Ð ÑÐ¾Ð´Ðµ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ»Ð¾ Ð¿Ð¾Ð´ÑÐ¾Ð±Ð½Ð¾ Ð¸Ð·ÑÑÐµÐ½Ð¾ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ ÐºÑÐµÐ°ÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð°, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°ÐºÐ¸Ñ Ð¿Ð¾Ð½ÑÑÐ¸Ð¹, ÐºÐ°Ðº ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð¸ Ð¼Ð°Ð»ÑÐ¹ Ð±Ð¸Ð·Ð½ÐµÑ. ÐÑÐ¾Ð±Ð»ÐµÐ¼Ð° Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ¾ÑÑÐ¾Ð¸Ñ Ð² Ð½ÐµÐ´Ð¾ÑÑÐ°ÑÐ¾ÑÐ½Ð¾Ð¹ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ñ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¹ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ ÐºÑÐµÐ°ÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ Ð°Ð³ÐµÐ½ÑÑÑÐ²Ð° âSONDER buroâ, Ð¾ ÑÐµÐ¼ ÑÐ²Ð¸Ð´ÐµÑÐµÐ»ÑÑÑÐ²ÑÑÑ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ ÑÐ¼Ð¿Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð°Ð²ÑÐ¾ÑÐ¾Ð¼. ÐÐ»Ñ ÑÐµÑÐµÐ½Ð¸Ñ Ð²ÑÑÐµÐ¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð½Ð¾Ð¹ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð°Ð²ÑÐ¾ÑÐ¾Ð¼ Ð±ÑÐ»Ð° Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð° ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ Ð¿ÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ, ÐºÐ¾ÑÐ¾ÑÐ°Ñ Ð¿Ð¾Ð¼Ð¾Ð¶ÐµÑ ÑÐ»ÑÑÑÐ¸ÑÑ Ð¸Ð¼Ð¸Ð´Ð¶ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸, Ð° ÑÐ°ÐºÐ¶Ðµ Ð¿Ð¾Ð²ÑÑÐ¸Ñ Ð»Ð¾ÑÐ»ÑÐ½Ð¾ÑÑÑ Ð¸ Ð¿ÑÐ¸Ð²Ð»ÐµÑÐµÑ Ð½Ð¾Ð²ÑÑ Ð°ÑÐ´Ð¸ÑÐ¾ÑÐ¸Ñ.
description: This work is devoted to the study of the concept of creative agency. During the theoretical part of the work was studied in detail the definition of creative agency, as well as such concepts as promotion strategy and small business. The problem of the graduate qualification work is the lack of effectiveness of existing promotion strategies of the creative agency âSONDER buroâ, as evidenced by the results of empirical research conducted by the author. To solve the above problem, the author proposed a promotion strategy that will help to improve the companys image, as well as increase loyalty and attract new audiences.
Design of a storage and retrieval model for multimedia data.
Creators: name: Wang, Ruihong.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Engineering, Electronics and Electrical.

description: One of the most important and challenging aspects in multimedia technology is the design of a storage and retrieval system that will support the recording and the playback of multimedia data from a secondary storage device. This multimedia storage and retrieval system must be capable of handling discrete media (i.e. text, images and graphics) and continuous media (i.e. audio, video and animation). It should also provide facilities to handle the synchronization information between two or more data objects in a multimedia application. In this thesis, multimedia technology and its applications are first introduced followed by a review of multimedia requirements. An overview of the current storage and retrieval techniques for multimedia information is then given. Following, our storage model for multimedia data is presented. This model can support the storage of both discrete media and continuous media on a hard disk, it also offers methods to store the synchronization information of data objects on the disk. Unlike conventional data placement techniques, a special storage pattern is used in the model for the storage of continuous media streams. By using the storage pattern, real-time constraint can be guaranteed during the retrieval of a continuous media stream. A control scheme for simultaneous retrieval of multiple streams is then discussed in a single disk head system. The control scheme can guarantee the continuous retrieval of multiple streams simultaneously. By combining this control scheme with buffering techniques, a dynamic access control algorithm is developed to control the acceptance of the new retrieval request. Computer simulation is used to help the analysis of the storage model and the simultaneous retrieval control scheme. The results show that the storage and retrieval model can provide a good storage efficiency, and can guarantee the continuous retrieval of delay sensitive media streams.
Defining and measuring the spatial dimension of accessibility.
Creators: name: Cameron, Nairne.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Geography.

description: This study combines a literature search and review with a real-world survey to identify, compare, and contrast techniques of measuring accessibility in conceptual and operational terms. An hypothesis-based approach is employed to ascertain how these techniques are used in the public and private sectors. With emphasis on the spatial dimension of accessibility, the thesis examines the definition of accessibility, the relative use of different accessibility measurement techniques, and the units used to measure spatial separation. The thesis also explores barriers to accessibility, the criteria and relative importance of spatial and aspatial factors in making location, network and routing decisions, and the use of GIS to implement accessibility measurement techniques. Results suggest that, despite differences in goals and/or objectives, there are similarities between the public and private sectors in both the conceptual and operational aspects of accessibility measurement, the criteria used to make location and transportation network decisions, and the limited use of Geographic Information Systems (GIS) to implement accessibility measurement techniques.
An electrochemical quartz crystal microbalance study of the electrochemistry of 4,4'-bipyridyl at silver electrodes.
Creators: name: Pisharodi, Devi.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Chemistry, Physical.

description: This thesis describes the application of the Electrochemical Quartz Crystal Microbalance (EQCM) technique to the study of the electrochemistry of 4,4$\sp\prime$bipyridyl at silver electrodes. The Ag-Bpy system was originally studied because Bpy was found to act as a promoter for the redox protein cytochrome c when adsorbed at silver electrodes. The system is also reported to display many phenomena (such as complex and film formation) that should be observable with the EQCM. Chapter 3 describes a study of the oxidation of Ag in the presence of 4,4$\sp\prime\rm bipyridyl$ where the Ag$\sp+$ and bipyridyl form a complex. The observed mass changes are found to result from the superposition of a mass loss due to the release of Ag$\sp+$ into solution and a mass gain from complex precipitation. When higher concentrations of Bpy (2mM) are used, complex formation is the dominant process that contributes to the mass change and so a simple mass increase is seen until the potential is extended further positive such that the surface concentration of bipyridyl is depleted significantly. Electrode corrosion then becomes the principal process causing the observed mass change to be a net decrease. In Chapter 4, the reduction of 4,4$\sp\prime$bipyridyl was studied at electrodeposited Ag electrodes in 0.1M Na$\sb2$SO$\sb4.$ Thus in contrast to the oxidation experiments where silver is the redox active species, it is the bipyridyl that is the redox active species in the reduction experiments. At high negative potentials a film of reduced Bpy develops on the electrode surface and its growth, development and removal can be observed and controlled by monitoring the mass responses. Both systems studied provide an illustration of the extra insight into surface processes at electrodes that the EQCM method provides, relative to cyclic voltammetry alone. (Abstract shortened by UMI.)
Developing harm reduction in the context of youth substance use: insights from a multi-site qualitative analysis of young people’s harm minimization strategies
Creators: name: Jenkins, Emily (Emily K.), 1981-
name: Slemon, Allie
name: Haines-Saah, Rebecca J.
Publisher: name: BioMed Central
Year: 2017

description: Background: Youth substance use programming and educational strategies are frequently informed by prevention approaches that emphasize abstinence goals, which often do not resonate with youth in their lack of acknowledgment of young people’s social context and how young people perceive positive effects of substance use. Further, approaches to drug prevention have been critiqued as adopting a one-size-fits-all approach and therefore inadequate in addressing substance use in the context of population variation and inequities. In response to the limitations of current approaches to prevention, programming informed by harm reduction principles that aims to minimize harms without requiring abstinence is emergent in school settings. However, youth perspectives informing harm reduction are limited in both research and program development. Methods: This paper draws on data from the Researching Adolescent Distress and Resilience (RADAR) study, which utilized an ethnographic approach to bring youth voice to the literature on mental health and substance use. Qualitative data collection included individual interviews (n = 86) with young people aged 13–18 across three communities—representing urban, suburban, and rural geographies—in British Columbia, Canada. A multi-site qualitative analysis of interview data was conducted to identify themes across and within each research site. Results: Across all three sites, young people’s individual experiences of substance use were shaped by geographic, socio-cultural, and political contexts, with youth describing their use in relation to the nature of substance use in peer groups and in the broader community. To manage their own substance use and reduce related harms, youth employed a variety of ad hoc harm minimization strategies that were reflective of their respective contexts. Conclusions: The findings from this study suggest the importance of harm reduction approaches that are contextually relevant and responsive to the lived experiences of youth. Youth perspectives in the development of harm reduction programming are needed to ensure that approaches are relatable and meaningful to young people, and effective for promoting the minimization of substance-related harms.
Impact of peatlands on carbon dioxide (CO2) emissions from the Rajang River and Estuary, Malaysia
Creators: name: Muller-Dum, Denise
name: Warneke, Thorsten
name: Rixen, Tim
name: Muller, Moritz
name: Baum, Antje
name: Christodoulou, Aliki
name: Oakes, Joanne
name: Eyre, Bradley D.
name: Notholt, Justus
Publisher: name: Swinburne
Year: 2024

description: Tropical peat-draining rivers are known as potentially large sources of carbon dioxide (CO2) to the atmosphere due to the high loads of carbon they receive from surrounding soils. However, not many seasonally resolved data are available, limiting our understanding of these systems. We report the first measurements of carbon dioxide partial pressure (CO2) in the Rajang River and Estuary, the longest river in Malaysia. The Rajang River catchment is characterized by extensive peat deposits found in the delta region, and by human impact such as logging, land use and river damming. CO2 averaged 2540±189 μatm during the wet season and 2350±301 μatm during the dry season. Using three different parameterizations for the gas transfer velocity, calculated CO2 fluxes to the atmosphere were 1.5 (0.5-2.0) g C m-2 d-1 (mean, minimum - maximum) during the wet season and 1.7 (0.6-2.6) g C m-2 d-1 during the dry season. This is at the low end of reported values for Southeast Asian peat-draining rivers, but similar to values reported for Southeast Asian rivers that do not flow through peat deposits. In the Rajang River, peatlands probably do not contribute much to the CO2 flux due to the proximity of the peatlands to the coast, which limits the opportunity for degradation of organic C during transport. Thus, we suggest that peat coverage is, by itself, insufficient as the sole predictor of CO2 emissions from peat-draining rivers, and that other factors, like the spatial distribution of peat in the catchment and pH, also need to be considered.
Patterns of molecular evolution at the amylase locus in Drosophila.
Creators: name: Abukashawa, Sumaia.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Biology, Genetics.

description: Genes encoding the starch-degrading enzyme, alpha-amylase, are found in all major groups of animals, plants and microbes. In this thesis, amylase-coding sequences have been chosen as a model system to investigate the patterns of molecular evolution in an enzyme-coding gene. Previous phylogenetic comparisons of amylase-coding sequences have shown high levels of primary sequence conservation over long evolutionary periods. The studies described here have concentrated on the evolution of these genes within the genus Drosophila. I have studied patterns of genetic variation within populations of a single species, Drosophila melanogaster, using two techniques: (i) allozyme variation and (ii) restriction fragment length polymorphisms (RFLPs). In order to get more precise information on the intraspecific patterns of variation, I have also isolated and partially sequenced the amylase genes from a wildtype strain of D. melanogaster. This sequence was compared to the known sequences which have already been described for laboratory strains. The work was extended to interspecific comparisons by studying amylase sequences from species that were closely-related to D. melanogaster (in this case D. erecta), and also a distantly-related species (D. virilis). This involved the isolation and sequencing of the amylase gene from a D. virilis genomic library. The results revealed several interesting patterns in the evolution of: (i) the primary gene sequences (e.g., gene conversion and codon bias), (ii) gene structure (e.g., changes in intron frequency and location) and (iii) gene organization (e.g., variation in the number of gene copies). These results, concerning both short-term and long-term patterns of molecular evolution within the genus Drosophila, are discussed in the context of what is currently known about patterns of molecular evolution in general, and about the molecular evolution of amylases in particular.
title: Essays on Private Antitrust Enforcement
Creators: name: Welter, Dominik
Publisher: name: University of Bayreuth
Year: 2020
Subjects: subject: cartel damages
subject: damage apportioning
subject: cartel deterrence
subject: cartel stability
subject: Shapley value
subject: joint liability
subject: relative responsibility
subject: rule of contribution
subject: umbrella effects
subject: 330

description: This thesis studies the economic impact of private antitrust enforcement on competition and on cartel members’ compensation payments. After Chapter 1’s short introduction to the topic, Chapter 2 investigates the effects of compulsory compensation for umbrella losses on competition. These losses arise when the price increase by the cartel results in a general price increase in the market concerned, i.e., customers who bought a product produced by a cartel outsider also had a damage. Chapters 3 and 4 analyse the internal allocation of compensation payments between cartel members in the EU. More specifically, Chapter 2 disproves the conventional wisdom that giving more customers a legal entitlement to compensation leads to more cartel deterrence and enhances competition. In a Bertrand-Edgeworth model it is shown that more stringent compensation provisions can have the opposite effect when the size of formed cartels is endogenous. In particular, compulsory compensation for umbrella losses deters small cartels, which have limited influence on the market price, and inadvertently stimulates formation of big encompassing cartels with significant price influence. Detected wrongdoers are commonly jointly and severally liable towards customers who successfully claimed for compensation, i.e., they may be forced to compensate victims on behalf of all. In the EU, they are internally liable in proportion to their “relative responsibility” for the harm. Chapter 3 operationalizes a firm’s relative responsibility by evaluating counterfactual damages had one or more cartelists rejected collaboration. Basic normative requirements – in particular causality – call for aggregation of counterfactual overcharges via the Shapley value. Damage allocations for linear market environments are characterized and bounds on payment obligations are established. Several ad hoc suggestions for deducing relative responsibility, e.g., from market shares or profits, are evaluated. The chapter also provides a new decomposition of the Shapley value which can be useful for other applications. The applicability of the heuristics discussed in Chapter 3 is however limited for two reasons. First, they do not provide a good approximation of the Shapley value independently of firms’ characteristics. Second, none of the heuristics reflects the cartelists’ relative responsibility. Chapter 4 resolves this obstacle by arguing that simple games, used in game-theoretic analysis of voting, can provide a workable approximation of the crucial causal links that define responsibility. Moreover, numerical examples show the Shapley-Shubik index of simple games to reflect EU law better than ad hoc heuristics for a variety of linear market models.
Sacred Spaces, Public Goods: Affordable Housing Development in Boston’s Catholic Churches
Creators: name: Lechtchiner, Feigele
Publisher: name: Brandeis University
Year: 2023
Subjects: Sacred Space
Church Redevelopment
Affordable Housing
Community Organizing
Boston
Urban Studies

description: The purpose of this research is to investigate the redevelopment of two Catholic churches into affordable housing as a method of combating gentrification. Given that many closed churches in Boston are redeveloped into luxury housing, this research highlights rare cases of affordable housing church redevelopment projects. Through conducting seven semi structured interviews with key actors and stakeholders in the ongoing redevelopment of Blessed Sacrament Church in Jamaica Plain and St. Katharine Drexel Parish in Roxbury, I examine the extent to which sacred spaces are considered a tool for communities fighting for ‘the right to stay put.’ These interviews revealed that despite secularization, city residents continue to interpret churches as public spaces over which they exercise ownership. While both projects are driven by actors with differing motivations, each case serves to preserve minority communities most vulnerable to advancing gentrification.  In the case of Blessed Sacrament Church, a diverse coalition of concerned city residents unified under the goal of creating affordable housing while preserving the church, a historical landmark in the community. On the other hand, the partnership between church leadership and the Planning Office of Urban Affairs, the affordable housing developer of the Archdioceses of Boston, to redevelop St. Katherine Drexel’s Parish Center was a means of ensuring the church’s own longevity while putting Black Catholic values into practice. Church redevelopment projects meant to benefit low-income and minority communities differ significantly on a case-by-case basis and little has been written to systematically explore how these redevelopments occur. This research aims to examine how church closures and transformations are dictated by their neighborhood context during gentrification. 
Enhancement of DNA immunization against hepatitis B following coexpression of costimulatory molecules.
Creators: name: Balasubramanian, Sowmya.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Biology, Molecular.

description: The use of plasmid DNA encoding antigens has given rise to a novel class of vaccines, that may overcome many of the disadvantages associated with classical antigen-based vaccines. This thesis examines specific methods of optimizing immune responses directed against the hepatitis B virus surface antigen (HBsAg) encoded by a plasmid expression system in BALB/c mice. Interaction of B7.1 and B7.2 with their receptor CD28/CTLA-4 molecules on T cells is known to facilitate progression of the T cell through the cycle of immune activation. We have determined whether coexpression of costimulatory molecules, B7.1 or B7.2, along with HBsAg from a DNA vaccine, administered as separate plasmids (codelivery) or encoded within the same expression vector (colinear expression), can augment HBsAg-specific humoral and cell-mediated responses. Intramuscular (IM) coexpression of B7.1 or B7.2 along with the DNA vaccine significantly enhanced cytotoxic T lymphocyte (CTL) responses whereas coexpression of B7.2 alone enhanced CTL responses with intradermal (ID) administration. However, there was no concomitant increase in humoral responses with coexpression by either route of administration. In contrast colinear expression of B7.1 or B7.2 significantly enhanced humoral as well as CTL responses with both IM and ID routes of administration. Furthermore, the Th2 bias that is seen with ID administration is skewed towards a Th1 response with B7 coexpression. The kinetics of plasmid DNA distribution in various anatomical compartments were also studied in order to address the differences in immune responses noted with IM and ID routes of administration. Collectively the results suggest that B7 coexpression can augment or alter responses to DNA vaccines and might prove effective for immunization in humans.
Permeation of pure gases through polyamide membranes and laminated polyamide membranes.
Creators: name: Stanisic, Frank Joseph.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, Chemical.

description: Asymmetric polyamide membranes of different porosities were prepared by varying the oven evaporation times. Permeation rates of hydrogen, helium, methane, nitrogen, oxygen, and carbon dioxide, for pressures between 345 and 2068 kPa, were measured for the above membranes and for the same membranes laminated with silicone rubber. The surface force pore flow model was employed to characterize and subsequently predict the permeation rates through the polyamide membranes; whereas, the modified resistance model was employed to analyze the experimental data of the laminated membranes. Membrane performance for various substrate porosities and lamination thicknesses were simulated by the modified resistance model.
title: Heuristic Approaches to Solve the Frequency Assignment Problem
Creators: name: Whitford, Angela Tracy
Publisher: name: Goldsmiths, University of London
Year: 1999

description: The frequency assignment problem is a computationally hard problem with many applications including the mobile telephone industry and tactical communications. The problem may be modelled mathematically as a T-colouring problem for an undirected weighted graph; it is required to assign to each vertex a value from a given set such that for each edge the difference in absolute value between the values at the corresponding vertices is greater than or equal to the weight of the edge. This problem was solved using novel and existing metaheuristic algorithms and their relative successes were compared. Early work of this thesis used greedy, steepest descent and backtracking algorithms as a means of investigating the factors which influence the performance of an algorithm (selection of frequency, ordering of variables, provision of an incremental objective function). Later simulated annealing, tabu search and divide and conquer techniques were used and the results compared. A novel divide and conquer technique incorporating metaheuristics is described and results using test data based on real problems is presented. The divide and conquer technique (with either tabu search or simulated annealing) was found to improve significantly upon the corresponding metaheuristic when implemented alone and acting on non-trivial scenarios. The results were significant and consistent. The divide and conquer (with simulated annealing) algorithm in particular was shown to be robust and efficient in its solution of the frequency assignment problems presented. The results presented in this thesis consistently out-perform those obtained by the Defence, Evaluation and Research Agency, Malvern. In addition this method lends itself to parallelisation since the problem is broken into smaller independent parts. The divide and conquer algorithm does not exploit knowledge of the constraint network and should be applicable to a number of different problem domains. Algorithms capable of solving the frequency assignment problem most effectively will become valuable as demand for the electromagnetic spectrum continues to grow.
Impusando la curaduría experta: the El metablog OpenMethods
Creators: name: Tóth-Czifra, Erzsébet
Publisher: name: Zenodo
Year: 2020
Subjects: Digital Humanities

description: Impusando la curaduría experta: the El metablog OpenMethods
 Erzsébet Tóth-Czifra Open Publishing Fest 29/5/2020
Uaica juruena Rheims, 2025, gen. et sp. nov.
Creators: name: Rheims, Cristina A.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Sparassidae
Uaica
Uaica juruena

description: Uaica juruena gen. et sp. nov.
urn:lsid:zoobank.org:act: 17F3E4F3-A34B-404C-B11A-3DDD5636BD26
Figs 6–7, 15
Diagnosis
Females resemble those of U. carapiranga gen. et sp. nov. (Figs 4C–D, 5D–F) by the epigyne with MS shaped as an inverted Y, bearing median EP (MS elongate with anterior EP in U. uatuma gen. et sp. nov.). They are distinguished from those of the latter species by the LL touching posteriorly and EP almost 3 × as long as wide (Figs 6C, 7A), and IDS tightly twisted, with five turns (Figs 6D, 7B–C) (LL not touching posteriorly, EP roughly as wide as long and IDS lightly twisted with three turns in U. carapiranga). Males are unknown.
Etymology
The specific epithet refers to the Juruena River that borders the type locality of the species, São Nicolau Farm; noun in apposition.
Type material
Holotype BRAZIL – Mato Grosso State • ♀; Cotriguaçu; Fazenda São Nicolau; [10.1326º S, 58.1412º W]; Jan. 2018; G. Almeida leg.; IBSP 233305.
Description
Female (holotype)
COLOR. Prosoma pale yellow, slightly darker along thoracic striae and eye area; fovea pale brown; eye borders black; legs, pedipalps and chelicerae pale yellow; labium pale brown distally pale yellow. Endites pale yellow, distally lighter; sternum pale yellow with slightly darker margins; opisthosoma covered with marbled white irregular marks; dorsally with cardiac mark pale gray with spidery lines extending laterally; ventrally with pale gray median longitudinal band and parallel lines of muscle impressions; spinnerets pale yellow (Fig. 6A–B).
MEASUREMENTS. Total length 8.5. Prosoma: 3.4 long, 3.0 wide. Opisthosoma: 5.0 long, 3.1 wide. Eyes: diameters 0.20, 0.20, 0.12, 0.17; interdistances 0.24, 0.20, 0.40, 0.34, 0.19, 0.17. Legs (2143): I: 14.8 (4.0, 1.6, 4.0, 4.1, 1.1); II: 16.9 (5.0, 1.8, 4.6, 4.3, 1.2); III: 10.8 (3.3, 1.3, 2.7, 2.5, 1.0); IV: 13.0 (3.9, 1.3, 3.4, 3.4, 1.0).
EPIGYNE. EF longer than wide; LL touching each other posteriorly; MS slightly less than 2 × as long as wide; EP triangular 3 × as long as wide; CO anterior, at lateral margins of MS (Figs 6C, 7A).
VULVA. IDS with first winding hook-shaped, running anteriorly as double helix; GP arising from last turn, closer to FD; FD antero-laterad (Figs 6D, 7B–C).
Male
Unknown.
Distribution
Only known from the type locality in the state of Mato Grosso (Fig. 15).
description: Published as part of Rheims, Cristina A., 2025, Uaica gen. nov., a new genus of huntsman spiders from the Brazilian Amazonia (Araneae: Sparassidae), pp. 24-49 in European Journal of Taxonomy 989 on page 35, DOI: 10.5852/ejt.2025.989.2879, http://zenodo.org/record/15323017
Race- associated molecular differences in uterine serous carcinoma
Creators: name: Friedman S
name: Pothuri B
name: Karpel H
name: Hacker K.E
name: Lara O.D
Publisher: name: Frontiers Media SA
Year: 2024

description: Purpose: Endometrial cancer (EMCA) is the most common gynecologic malignancy, and new diagnoses are increasing in the United States. Black patients are more likely to present with advanced stage, be diagnosed with high-risk uterine serous carcinoma (USC) and die of their cancer. Methods: Patients with endometrial adenocarcinoma who received tumor FoundationOne CDx testing at our institution between January 2017 and August 2022 were identified. Genomic alterations, demographic and clinical characteristics were collected. Descriptive statistics and Fisher’s exact test were used to analyze data. Results: A total of 289 patients (29.4% Black and 52.6% White) with advanced or recurrent endometrial adenocarcinoma underwent FoundationOne CDx testing. USC comprised 26.3% (76 of 289) of tested tumors. Of USC tumors, 33 of 76 (44%) were of Black race. USC occurred more frequently in Black patients (33 of 85 [38.8%] Black patients compared to 30 of 152 [19.7%] White patients, p<0.05). Among USC, CCNE1 amplification occurred more frequently in Black patients than in White patients (12 of 33 [36.36%] vs 2 of 30 [6.67%], p<0.05) while PI3K/AKT/mTOR pathway mutations occurred less frequently (16 of 33 [48.5%] vs 26 of 33 [86.7%], p=0.17). Among patients with CCNE1 amplification 73.3% (11 of 15) progressed on or within 12 months of first-line platinum-based therapy. CCNE1 amplification had significantly shorter median overall survival (97.3 months vs 44.3; HR (95%CI): 7.1 (10.03, 59.4) p< 0.05). Conclusions: Black patients constituted 44% of patients with USC in our study and had an increased frequency of CCNE1 amplification. Patients whose tumors harbored CCNE1 amplification had shorter overall survival. Identifying actionable mutations in this high unmet need population is crucial to improving outcomes among Black patients with uterine malignancy. Development of new targeted-therapies will need to keep these alterations at the forefront as trials are being designed.
Reduction of the quantization error in fuzzy logic controllers by dithering.
Creators: name: Mao, Jie.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Engineering, Electronics and Electrical.

description: Dithering technique has been used to reduce the quantization error for more than thirty years. This thesis reviews the theories of quantization and dithering, which explain the effect of dithering from a theoretical point of view. Applying dithering to digital Fuzzy Logic Controller (FLC) is the focus of this thesis. Two applications, FLC for Inverted Pendulum and FLC for Truck Backer-Upper, have been simulated and reported. The results of the simulation demonstrate the positive effect of input signal dithering on the resolution of the digital FLC output, especially for the case of the coarse quantization of the input signal.
L'inscription de la lecture dans L'hiver de force de Réjean Ducharme : lecteur fictif/lecteur réel.
Creators: name: Béland, Benoît.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Literature, Canadian (French).

description: L'oeuvre de Réjean Ducharme est l'objet de plusieurs études. Si le langage, la critique sociale et les jeux textuels sont souvent étudiés dans les écrits ducharmiens, l'étude de la lecture, pour sa part, demeure encore une approche nouvelle. D'ailleurs, L'Hiver de force , récit que nous analysons dans cette thèse, est rarement la source d'études et d'analyses poussées. C'est donc à partir du seul récit de Réjean Ducharme que nous nous sommes proposé d'étudier la lecture chez les personnages d'une part, mais d'autre part, celle pratiquée chez le lecteur réel. Ainsi, nous montrons, à l'aide des théories d'Umberto Eco et de Hans Robert Jauss principalement, ce que lisent André et Nicole Ferron, les deux protagonistes de l'histoire, pourquoi lisent-ils et, enfin, comment lisent-ils. Ces études nous conduisent donc à voir comment le couple s'insère dans le monde. Dans un deuxième temps, nous nous intéressons à l'analyse de la lecture que le lecteur réel fait de l'oeuvre en fonction de son bagage culturel et de celui que lui transmettent les personnages lecteurs du récit.
Enantiospecific syntheses of (+)-hyosamine and (-)-hyosamine, and stereospecific glycosylation of 2-deoxystreptamine.
Creators: name: Chen, Tong.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Chemistry, Biochemistry.

description: Two aminocyclitol antibiotics, hygromycin B and destomycin A, contain as a structural component optically active N-methyl(1,3/2,4,6)-4,6-diamino-1,2,3-trihydroxycyclohexanetriol (hyosamine). The (+)-enantiomer is present in the former antibiotic, and the ($-$)-enantiomer, in the latter. The present work describes enantiospecific syntheses of these two components, starting from a common chiral precursor, 1 scL-(1,3/2,4,6)-6-azido-1,2-O-isopropylidene-4-nitro-1,2,3-cyclohexanetriol. The precursor was prepared in 9 steps from scD-mannose according to a recently published procedure. Different sequential manipulations of its two unequal nitrogenous functions, converting these eventually into an amino and an N-methylamino group, led to the target compounds in enantiospecific fashion. Several approaches were explored, and one approach to (+)-hyosamine and two to ($-$)-hyosamine were successful. The above mentioned azidonitro precursor was also used for a synthesis of a blocked derivative of 2-deoxystreptamine (1,3-diamino-4,5,6-trihydroxycyclohexane) stereospecifically glycosylated in the 6-position. This was accomplished by conversion of the blocked azidonitrocyclitol into the corresponding diacetamido compound and coupling with acetobromoglucose.
Unmasking the role of SARS-CoV-2 Nsp14 on the host cell gene expression changes and Adapting Cas13 to Drosophila melanogaster
Creators: name: Zaffagni, Michela
Publisher: name: Brandeis University
Year: 2023
Subjects: Cas13
IMPDH2
Nsp14
SARS-CoV-2
Gene Expression

description: Abstract Chapter 1: Unmasking the role of SARS-CoV-2 Nsp14 on the host cell gene expression changesViral infection involves complex set of events orchestrated by multiple viral proteins. To identify functions of SARS-CoV-2 proteins, we performed transcriptomic analyses of cells expressing individual viral proteins. Expression of Nsp14, a protein involved in viral RNA replication, provoked a dramatic remodeling of the transcriptome that strongly resembled that observed following SARS-CoV-2 infection. Moreover, Nsp14 expression altered the splicing of more than 1,000 genes and resulted in a dramatic increase in the number of circRNAs, which are linked to innate immunity. These effects were independent of the Nsp14 exonuclease activity and required the N7-guanine-methyltransferase domain of the protein. Activation of the NFkB pathway and increased expression of CXCL8 occurred early upon Nsp14 expression. We identified IMPDH2, which catalyzes the rate-limiting step of guanine nucleotides biosynthesis, as a key mediator of these effects. Nsp14 expression caused an increase in GTP cellular levels, and the effect of Nsp14 was strongly decreased in presence of IMPDH2 inhibitors. Together, our data demonstrate an unknown role for Nsp14 with implications for therapy.
description: Abstract Chapter 2: Adapting Cas13 to Drosophila melanogaster
description: Manipulation of gene expression is one of the best approaches for studying gene function in vivo. CRISPR-Cas13 has the potential to be a powerful technique for manipulating RNA expression in diverse animal systems in vivo, including Drosophila melanogaster. Studies using Cas13 in mammalian cell lines for gene knockdown showed increased on-target efficiency and decreased off-targeting relative to RNAi. Moreover, catalytically inactive Cas13 fusions can be used to image RNA molecules, install precise changes to the epitranscriptome, or alter splicing. However, recent studies have suggested that there may be limitations to the deployment of these tools in Drosophila, so further optimization of the system is required. Here, we report a new set of PspCas13b and RfxCas13d expression constructs and use these reagents to successfully knockdown reporter transcripts in Drosophila cells. As toxicity issues have been reported with high level of Cas13, we effectively decreased PspCas13b expression without impairing its function by tuning down translation. Furthermore, we altered the spatial activity of both PspCas13b and RfxCas13d by introducing Nuclear Exportation Sequences (NES) and Nuclear Localization Sequences (NLS) while maintaining activity. Finally, we explored possible applications for catalytically inactive Cas13. Thus, we report new reagents for performing RNA CRISPR-Cas13 experiments in Drosophila, providing additional Cas13 expression constructs that retain activity.
Innovative Statistical Methods to Model and Evaluate Physical Activity Programs Engagement
Creators: name: Silva, Sampathawaduge Sandun Malpriya
Publisher: name: Swinburne
Year: 2024

description: According to recent statistics from the World Health Organization, 23% of people aged 18 years and over are not sufficiently physically active. At the same time online health, wellbeing and physical activity programs have become more popular. However, these online programs lack structured statistical and machine learning frameworks for enhancing engagement through program personalisation. This thesis fills this gap by developing a framework for monitoring and predicting future online engagement, including personalised achievable goals for daily step counts and systems for personalised participant intervention by administrators. It identifies new opportunities for online physical activity programs for producing better participant outcomes.
Portage Data Discovery Expert Group - Collections Development Working Group : Phase One Report
Creators: name: Vejvoda, Berenica
name: Ambi, Alison
name: Barsky, Eugene
name: Lindstrom, Kevin
name: MacDonald, Heather
name: Matthews, Kathleen
name: Moosberger, Michael
name: O'Hara, Lisa
name: Powelson, Susan
name: Silk, Kimberly
name: Sivak, Allison
name: Thompson, Kristi
Publisher: name: The University of British Columbia
Year: 2017

description: This working group is one of two working groups created to support the Portage Data Discovery Expert Group. The goal of the Collections Development Working Group is to ensure that Canadian research data is comprehensively included and indexed in the Federated Research Data Repository (FRDR) and other search tools to support its discovery and reuse
Uaica karipuna Rheims, 2025, gen. et sp. nov.
Creators: name: Rheims, Cristina A.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Araneae
Sparassidae
Uaica
Uaica karipuna

description: Uaica karipuna gen. et sp. nov.
urn:lsid:zoobank.org:act: E0DF65B2-179D-40FB-9587-CBCFAAADBC0D
Figs 8–9, 15
Diagnosis
Males of U. karipuna gen. et sp. nov. are distinguished from those of all congeners by the palps with T strongly projecting retroproximally and E arising at 5 o’clock position (Figs 8D, 9B) (T not projecting and E arising at 8:30 o’clock in the other species). Females are unknown.
Etymology
The specific epithet refers to the Karipuna indigenous people that currently inhabit an Indigenous Territory located in the municipalities of Porto Velho and Nova Mamoré, in Rondônia, Brazil; noun in apposition.
Type material
Holotype BRAZIL – Rondônia State • ♂; Porto Velho; [8.7500º S, 63.9000º W]; 15 Apr. 1996; Equipe IBSP/ SMNK leg.; IBSP 8691.
Other material examined
BRAZIL • 2 juvs; same vial as holotype; IBSP 8691.
Description
Male (holotype)
COLOR. Prosoma pale brown, darker along thoracic striae and lateral margins of cephalic region; fovea dark brown; eye borders black. Chelicerae pale brown as prosoma. Legs and pedipalps slightly lighter than prosoma. Labium brown, distally pale brown. Endites pale brow, distally lighter. Sternum orange brown with darker margins. Opisthosoma cream colored; dorsally with two pairs of faint whitish marbled marks along lateral margins of cardiac mark and six light brown chevron-like marks medially down posterior half; ventrally with pale brownish-yellow band with two parallel lines of muscle impressions. Spinnerets pale yellow (Fig. 8A–B).
MEASUREMENTS. Total length 7.6. Prosoma: length 3.2 long, 3.2 wide. Opisthosoma: 4.2 long, 2.2 wide. Eyes: diameters 0.24, 0.22, 0.16, 0.20; interdistances 0.18, 0.06, 0.34, 0.28, 0.14, 0.10. Legs (2143): I: 22.2 (5.9, 2.1, 6.3, 6.2, 1.7); II: 25.5 (7.0, 2.1, 7.4, 7.1, 1.9); III: 15.6 (4.6, 1.5, 4.2, 4.1, 1.2); IV: 18.8 (5.5, 1.5, 5.0, 5.3, 1.5).
PALP. RTA almost 2 × as long as wide, projecting away from tibia in ventral view and with curved tip in retrolateral view; ST visible prolaterally; sp running retrolaterally with strong medial indentation; C 2 × as long as wide, with very wide base; E filiform, longer than C (Figs 8C–E, 9).
Female
Unknown.
Distribution
Only known from the type locality, in the state of Rondônia (Fig. 15).
description: Published as part of Rheims, Cristina A., 2025, Uaica gen. nov., a new genus of huntsman spiders from the Brazilian Amazonia (Araneae: Sparassidae), pp. 24-49 in European Journal of Taxonomy 989 on pages 37-39, DOI: 10.5852/ejt.2025.989.2879, http://zenodo.org/record/15323017
Kitsap County 4-H Newsletter, February-March 2021
Creators: name: Washington State University Kitsap County Extension
Publisher: name: Washington State University
Year: 2021
Subjects: 4-H Club

description: Contents:
description: mportant Dates
description: In the Spotlight
description: 4-H in Kitsap County
description: State & National 4-H Opportunities
description: 4-H Fundraisers
description: Scholarship Opportunities
description: Volunteer News
description: 4-H Office Contact Information
Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study – findings from Pretest 1 of the German National Cohort
Creators: name: Akmatov, Manas K.
name: Koch, Nadine
name: Vital, Marius
name: Ahrens, Wolfgang
name: Flesch-Janys, Dieter
name: Fricke, Julia
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Bacterial infection
subject: Epidemiology
subject: Microbiome
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: We examined acceptability, preference and feasibility of collecting nasal and oropharyngeal swabs, followed by microbiome analysis, in a population-based study with 524 participants. Anterior nasal and oropharyngeal swabs were collected by certified personnel. In addition, participants self-collected nasal swabs at home four weeks later. Four swab types were compared regarding (1) participants’ satisfaction and acceptance and (2) detection of microbial community structures based on deep sequencing of the 16 S rRNA gene V1–V2 variable regions. All swabbing methods were highly accepted. Microbial community structure analysis revealed 846 phylotypes, 46 of which were unique to oropharynx and 164 unique to nares. The calcium alginate tipped swab was found unsuitable for microbiome determinations. Among the remaining three swab types, there were no differences in oropharyngeal microbiomes detected and only marginal differences in nasal microbiomes. Microbial community structures did not differ between staff-collected and self-collected nasal swabs. These results suggest (1) that nasal and oropharyngeal swabbing are highly feasible methods for human population-based studies that include the characterization of microbial community structures in these important ecological niches, and (2) that self-collection of nasal swabs at home can be used to reduce cost and resources needed, particularly when serial measurements are to be taken.
Figure: The Media Literacy Theory of Change with the Message Interpretation Process Model for assessment
Creators: name: Domgaard, Shawn K.
name: Austin, Erica W.
Publisher: name: Edward R. Murrow Center for Media & Health Promotion Research, Edward R. Murrow College of Communication, Washington State University
Year: 2024

description: This figure portrays an integrated model of the Media Literacy Theory of Change and the Message Interpretation Process Model, thereby explaining how people progress along the steps involved in critical thinking about sources and content of media messages to make decisions about what is real, what is important and what behaviors to adopt, applying emotion and logic to assess the meaning of media messages they encounter.
Groupe d’experts sur la découverte des données – Groupe de travail sur le développement des collections : rapport de la phase 1
Creators: name: Vejvoda, Berenica
name: Ambi, Allison
name: Barsky, Eugene
name: Lindstrom, Kevin
name: MacDonald, Heather
name: Matthews, Kathleen
name: Moosberger, Michael
name: O'Hara, Lisa
name: Powelson, Susan
name: Silk, Kimberly
name: Sivak, Allison
name: Thompson, Kristi
Publisher: name: The University of British Columbia
Year: 2017

description: Ce groupe de travail est l’un des deux groupes créés pour épauler le Groupe d’experts sur la découverte des données du réseau Portage. L’objectif du Groupe de travail sur le développement des collections consiste à veiller à ce que les données de recherche canadiennes soient complètement incluses et indexées dans le Dépôt fédéré de données de recherche (DFDR) et dans d’autres outils de repérage afin de favoriser leur découverte et leur réutilisation
UHPLC-Q/TOF-MS-based Ecometabolomic Study of Nepenthaceae
Creators: name: Wong, Changi
Publisher: name: Swinburne
Year: 2024

description: Nepenthes, also known as tropical pitcher plant, is found with the capability to tolerate temperature stress in their natural habitat. The understanding on the adaptation mechanisms acquired by the plant toward the temperature stress is, however, limited. In this study, we investigated the impact of heat and cold stresses on different groups of Nepenthes species, as well as to verify the traditional use of Nepenthes as a medicinal plant. This study highlighted the metabolic responses and adaptation strategies among the Nepenthes species, as well as supported the potential traditional application of Nepenthes as medicinal plant by the indigenous communities.
Septic systems in North Carolina: A neglected half of the state?
Creators: name: Muoghalu, Chimdi
name: Manga, Musa
name: Kryston, Amy
name: Lebu, Sarah
name: Sprouse, Lauren
name: Woods, Courtney
Publisher: name: Public Library of Science
Year: 2024

description: Millions of Americans, especially those in rural and marginalized communities, rely on septic tanks and other forms of onsite sanitation (OSS) systems to meet their sanitation needs. Roughly half of North Carolina’s (NC) population uses septic systems, compared to about a quarter nationwide. NC has the second highest rural population among all states but ranks 17th in terms of the share of its population classified as rural—thus, rurality is not the sole reason that such a large portion of NC’s population relies on septic systems. Although septic systems are common in widely dispersed rural areas where piped sewer systems are impractical, they are also found in densely populated communities near cities with centralized services. Extending water and sewer infrastructure to these areas may create jobs and boost local economies, though key challenges associated with extending public services include lack of financing, government support, community engagement, and the presence of existing septic system infrastructure. As population growth, development pressure, and costs of centralized wastewater treatment systems continue to increase, the use and construction of OSS systems in NC are projected to increase as well.