cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Examining Spatial Distribution of Adult Glioma Incidence using SEER Data 2001-2014
Creators: name: Hicks, Marissa
Publisher: name: Georgia State University
Year: 2018

description: INTRODUCTION: Gliomas are most common and fatal primary brain neoplasms, with few known risk factors. High dose ionizing radiation is the only known environmental risk factor. Previous studies show Caucasians having greater rates compared to African Americans, and higher rates of glioblastoma found in areas with higher socio-economic status (SES), suggesting involvement of SES-related factors. We examine spatial distribution of glioma incidence in Caucasians and African Americans to determine geographical disparities related to race, SES, and radon.
AIM: To determine whether geospatial clusters of high glioma incidence exist, intending to identify potential environmental risk factors in areas with high glioma risk.

METHODS: Data from Surveillance, Epidemiology, and End Results (SEER) Program 2001-2014 were used to generate descriptive statistics for adult glioma. Global Moran’s I test was performed for glioma rates, radon levels, and SES contextual factors and predicated use of Local Indicator of Spatial Association analysis, and results were compared.

RESULTS: Glioma rates per 100,000 were highest for ages 70-79 (18.85, 95% CI: 17.96-19.75). Incidence rates were more than twice greater for Caucasians, 7.86 (7.65-8.07), compared to African Americans, 3.48 (2.66-4.30), and other races 2.83 (1.48-3.80). County rates varied from 0 to 27.84 for all races combined.

CONCLUSION: High and low rates of glioma are not spatially random, indicating environmental risk factors for glioma. Racial disparity in glioma is persistent. An inverse relationship with low SES is demonstrated, while a positive correlation is seen with radon. Understanding risk factors and focus on high-rate areas could lead to development of prevention.
Sex differences in clinical features, utilization of oral anticoagulant agents, and 1-year outcome in Middle Eastern patients with atrial fibrillation
Creators: name: Alrabadi, Nasr
name: Al-Nusair, Mohammed
name: Haddad, Razan
name: Alghizzawi, Basheer S.
name: Al-Nusair, Nashmi
name: Mohammad, Saleh Alhaj
name: Shteiwi, Saif M.
name: El-zubi, Maryam K.
name: Marie, Zaid
name: Alnsour, Ayham
name: Jarrah, Mohamad
name: Alzoubi, Karem H.
name: Hammoudeh, Ayman
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Studies have revealed that sex can predict differences in multiple aspects of atrial fibrillation (AF). These differences are underreported in the Middle East. This study aims to describe sex-specific differences in risk factors, symptomatology, management, and outcomes in Middle Eastern patients with AF. The JoFib (Jordan-Atrial-Fibrillation) study is an observational, prospective, multicenter, nationwide registry in AF. Comparisons were made between female and male patients using Pearson chi-square and Mann-Whitney U tests. Multivariable regression models were constructed to investigate whether the female sex was predictive of any AF-related outcomes (all-cause death, cardiovascular death, ischemic stroke or systemic embolism [IS/SE], major bleeding, and clinically relevant non-major bleeding). Of 2,020 patients with AF, 54% (n = 1091) were females. Females with AF were older (median age 71 vs. 69, p <.001), but had less heart failure (20.9% vs. 27.2%, p = .001) and coronary artery disease (7.5% vs. 14.7%, p <.001). Females with AF were more symptomatic (74.7% vs. 66.5%, p <.001) and frequently received anticoagulant therapy (84.4% vs. 78.9%, p = .001). Rhythm control was pursued less frequently in females (23.4% vs. 27.3%, p = .04). All studied outcomes occurred with similar frequencies in females and males, and sex was not significantly predictive of any outcome. Females with AF are more symptomatic, yet they are treated less with rhythm control. Despite higher risk, females have similar risk-adjusted all-cause cardiovascular death and stroke rates compared to males. Future studies should explore how treatments and interventions can influence quality-of-life and cardiovascular outcomes in females with AF.
Sex differences in clinical features, utilization of oral anticoagulant agents, and one-year outcome in Middle Eastern patients with atrial fibrillation
Creators: name: Alrabadi, Nasr
name: Al-Nusair, Mohammed
name: Haddad, Razan
name: Alghizzawi, Basheer S.
name: Al-Nusair, Nashmi
name: Mohammad, Saleh Alhaj
name: Shteiwi, Saif M.
name: El-zubi, Maryam K.
name: Marie, Zaid
name: Alnsour, Ayham
name: Jarrah, Mohamad
name: Alzoubi, Karem H.
name: Hammoudeh, Ayman
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Studies have revealed that sex can predict differences in multiple aspects of atrial fibrillation (AF). These differences are underreported in the Middle East. This study aims to describe sex-specific differences in risk factors, symptomatology, management, and outcomes in Middle Eastern patients with AF. The JoFib (Jordan-Atrial-Fibrillation) study is an observational, prospective, multicenter, nationwide registry in AF. Comparisons were made between female and male patients using Pearson chi-square and Mann-Whitney U tests. Multivariable regression models were constructed to investigate whether the female sex was predictive of any AF-related outcomes (all-cause death, cardiovascular death, ischemic stroke or systemic embolism [IS/SE], major bleeding, and clinically relevant non-major bleeding). Of 2,020 patients with AF, 54% (n = 1091) were females. Females with AF were older (median age 71 vs. 69, p < 0.001), but had less heart failure (20.9% vs. 27.2%, p = 0.001) and coronary artery disease (7.5% vs. 14.7%, p < 0.001). Females with AF were more symptomatic (74.7% vs. 66.5%, p < 0.001) and frequently received anticoagulant therapy (84.4% vs. 78.9%, p = 0.001). Rhythm control was pursued less frequently in females (23.4% vs. 27.3%, p = 0.04). All studied outcomes occurred with similar frequencies in females and males, and sex was not significantly predictive of any outcome. Females with AF are more symptomatic, yet they are treated less with rhythm control. Despite higher risk, females have similar risk-adjusted all-cause cardiovascular death and stroke rates compared to males. Future studies should explore how treatments and interventions can influence quality of life and cardiovascular outcomes in females with AF.
Use of High-resolution Metabolomics to Assess Changes in Metabolic Pathways Associated with Acute Exposure to Air Pollutants.
Creators: name: Finlon, Elizabeth
Publisher: name: Georgia State University
Year: 2018

description: INTRODUCTION: Many studies have examined the positive effects of physical activity on mortality and morbidity, as well as the negative impact of exposure to air pollutants. Few, however, have investigated the complex interaction between physical activity and air pollution exposure. One promising method for analyzing this interaction is using metabolomics to identify the resulting metabolites produced from each exposure. This study will provide insight into the modification by physical activity of health biomarkers associated with acute exposure to air pollutants.
AIM: The aim of this study is to identify novel biomarkers of pollutant exposures using metabolomics analyses. Specifically, this study will examine differences in exposures to air pollutants (black carbon, ozone, particulate matter, particle number concentration) and corresponding metabolic changes in subjects before and after outdoor physical activity.
METHODS: Sixty-five saliva samples for metabolomics analysis were collected from a sample of 57 individuals in Atlanta, GA from June through July 2016. The ambient outdoor concentrations of PM2.5 (PM), ozone (O3), black carbon (BC), and particle number concentration (PNC) were measured throughout each 2-hr sampling event. Each participant’s physical activity levels were monitored as well. Each pollutant (above) was analyzed per individual via four separate metrics: ambient outdoor concentration, exposure, cumulative inhaled dose, and maximum one-minute dose. Samples were processed via ultra-high resolution liquid chromatography-mass spectrometry. Various mixed regression models used pollutant metrics to predict changes in metabolic feature intensity from pre- to post-exposure. Metabolite identification and pathway analysis for each significant feature was calculated using Mummichog version 1.0.3 with a level of significance of .05.
 RESULTS: All pollutant metrics were significantly associated with changes in metabolic features. PNC max showed the highest number of significant associations with 172 significantly associated metabolic features. Additionally, Mummichog analysis yielded significant pathway predictions for all feature metrics, with a total of 48 significant metabolic pathway predictions
DISCUSSION: We identified 48 metabolic pathways that showed significant correlation with air pollution exposure. However, the lack of consistency in pathway predictions suggests that acute pollution exposure may take more than 2 hours to have a measurable effect on the salivary metabolome. Our research suggests that while high-resolution metabolomics shows potential for reliably identifying biomarkers of pollutant-related stress, there is still much room for further development in this field.
Supplementary document for Visible and near-infrared dual-band switchable metasurface-enabled edge imaging - 5953079.pdf
Creators: name: Chen, Guanghao
name: Zhou, Junxiao
name: Bopp, Steven
name: Zhao, Junxiang
name: Liu, Zhaowei
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supplementary infomation
Determinants of Childhood Stunting in Guinea: Further Analysis of Demographic and Health Survey 2012
Creators: name: Bangoura, Abdoulaye
Publisher: name: Georgia State University
Year: 2018

description: Background: Childhood stunting remains a major public health problem in developing countries because of its association with increased morbidity and mortality. In Guinea, the prevalence of childhood stunting has increased from 30.5% to 31.2% between 1999 and 2012. This study aimed to identify factors associated with stunting and severe stunting among children aged less than five years in Guinea.
Methods:The study used a cross-sectional data from the 2012 Guinean Demographic and Health Survey which included 3176 children aged 0-59 months. The 2016 WHO Height-for-age Z-score (HAZ) was used to classify stunting as moderate stunting (HAZ
Results: The prevalence of child stunting was higher in boys (32.69%) than in girls (29.12%). Age was a significant determinant of stunting with the highest odds among children aged 24-35 months (Adjusted OR=6.82; 95%CI=4.37, 10.63). Children from Mamou (Adjusted OR=2.17 95% CI 1.16, 4.05) and N’zerekore (Adjusted OR=2.05 95% CI 1.15, 3.66) were more likely to be stunted compared to those from the capital city Conakry. The other factors associated with growth faltering were wealth index (poorest, poorer, and middle), short birth interval (less than 24 months, 24 to 47 months), mother’s low body mass index (less than 18.5 kg/m2) and source of drinking water (unimproved).
Conclusion: Our findings suggest that intervention to address childhood stunting in Guinea should focus on poverty alleviation as well as improving women’s nutrition, child feeding practices, household sanitation and family planning.
Alcohol Consumption and Marijuana Use Interaction with Metabolic Syndrome among United States Adults: Analysis of NHANES 2013-2014.
Creators: name: Akande, Pius
Publisher: name: Georgia State University
Year: 2018

description: INTRODUCTION: The relationship between alcohol, marijuana and metabolic syndrome remains controversial. Marijuana has been found to be a commonly used drug among those who drink alcohol, yet little is known about the effect of using both substances concurrently with metabolic syndrome. With decriminalization of marijuana across different states in the United States, it is expected that the prevalence of marijuana use will increase. Therefore, it is of utmost importance to understand the adverse impact of these drugs on metabolic syndrome.
AIM: This study aims to understand (a) the relationship between alcohol and marijuana use and metabolic syndrome (b) the association between concurrent use of alcohol and marijuana and metabolic syndrome, and (c) the statistical interaction of alcohol and marijuana use on metabolic syndrome using the National Health and Nutrition Examination Survey data.
METHODS: A cross-sectional analysis of 2013-2014 National Health and Nutrition Examination survey data was conducted. Participants aged ?20 years were eligible. Metabolic syndrome was defined by the International Diabetes Federation criteria. The adjusted odds ratio of metabolic syndrome was calculated controlling for variables fitted using stepwise logistic regression model selection.
RESULTS: After adjusting for age, race, educational level, marital status, poverty, and cigarette smoking status; current drinkers showed a significant inverse association with metabolic syndrome (aOR, 0.69 95% CI, 0.49-0.99). The odds of metabolic syndrome in concurrent users (aOR 0.53 95% CI, 0.28-0.99) was less than the odds among non-concurrent users. Compared with young adults, middle-aged and older adults had increased odds of metabolic syndrome.
DISCUSSION: This data indicates that alcohol consumption and co-use of alcohol and marijuana is associated with a lower prevalence of metabolic syndrome. Longitudinal studies are needed to confirm these findings. Notably, age and smoking are significant predictors of metabolic syndrome.
The Association Between the 2014 Medicaid Expansion and Screening Colonoscopy and Sigmoidoscopy Receipt for Adults Aged 50-75 Years
Creators: name: Gilbert, Madison
Publisher: name: Georgia State University
Year: 2018

description: BACKGROUND: In 2014, more than fifty thousand Americans died of colorectal cancer (CDC). Adults between the ages of fifty and seventy-five are urged to be obtain colorectal cancer screenings. The United States Congress voted the Patient Protection and Affordable Care Act (ACA) into law in 2010. Medicaid expansion began in 2014. States could opt in to have their Medicaid expansion, with the federal government paying for most of the additional cost.
AIMS: This study investigates whether the rates of adults ages 50-75 receiving a colorectal cancer screening has significantly changed from 2008 (pre-ACA) to 2016 (post ACA and Medicaid expansion) by analyzing states that did expand Medicaid as compared to those states that did not.
METHODS: This study utilizes the Behavioral Risk Factor Surveillance System (BRFSS) data from 2008 and 2016 to explore the changes in rates of colorectal screening between a selection of states that expanded and failed to expand Medicaid. The data is analyzed in SAS 9.4, utilizing PROC FREQ to analyze the categorical variables and PROC GENMOD to produce marginal models.
RESULTS: Subjects in states that did not participate in the Medicaid expansion in January 2014 were 0.90 [0.80, 1.01] times as likely to have received a screening sigmoidoscopy or colonoscopy than participants in states that did participate in the Medicaid expansion.
DISCUSSION: The marginal model failed to show a statistically significant difference in receipt of sigmoidoscopy or colonoscopy between participants who lived in Medicaid expanded states and non-expanded states; the p-value is greater than the alpha of 0.05 and the 95% confidence interval contains 1. This suggests the Medicaid expansion did not have a significant impact on receipt of sigmoidoscopy or colonoscopy.
Epidemiological and economic impact of pandemic influenza in Chicago: priorities for vaccine interventions
Creators: name: Nargesalsadat Dorratoltaj
name: Achla Marathe
name: Lewis, Bryan
name: Samarth Swarup
name: Eubank, Stephen
name: Abbas, Kaja
Publisher: name: F1000Research
Year: 2016

description: The objective of this study is to evaluate the direct and indirect impact of vaccine-based interventions for prevention and control of an influenza pandemic, for the city of Chicago, using a dynamic agent based model.
Supplementary document for Improving the laser performance of ion beam sputtered dielectric thin films through the suppression of nanoscale defects by employing a xenon sputtering gas - 5953189.pdf
Creators: name: Mirkarimi, Paul
name: Harthcock, Colin
name: Qiu, S. Roger
name: Negres, Raluca
name: Guss, Gabriel
name: Voisin, Thomas
name: Hammons, Josh
name: Colla, Chris
name: Mason, Harris
name: Than, Anton
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental text
Carbapenem-resistant Enterobacteriaceae (CRE) Case Definition Change: A Comparative Study of the Georgia Emerging  Infections Program, 2011-2015 and 2016
Creators: name: Williams, Jeremiah
Publisher: name: Georgia State University
Year: 2018

description: Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) infections, with limited treatment options, pose a significant public health challenge. In 2011, the CDC’s phenotypic CRE case definition was nonsusceptibility to ? 1 carbapenem and resistance to 3rd generation cephalosporins but changed January 2016 to resistance to any carbapenem (including ertapenem). This study seeks to determine if this change influenced significant differences in patient characteristics.
Methods: CRE cases in Metro Atlanta, Georgia were collected from 2011-2016. Cumulative incidence per 100,000, odds ratios, and ?2estimates were calculated to identify trends. A univariable analysis was conducted to examine risk factors. Adjusting for covariates, the final multivariable model included invasive infection as the outcome and the new definition as the predictor.
Results: A total of 1,144 CRE cases were confirmed from 2011-2016 in Metro Altanta. CRE incidence rates for all culture sources decreased pre-and post-definition change from 9.4 to 1.6. Central venous catheters and ICU stay 7 days prior, had the strongest association with invasive CRE infections; pre-(OR 5.9, 95% CI 1.4-4.3) and post-(OR 11.2, 95% CI 4.9-25.6) definition change. In the final model, the new definition (OR 0.6, 95% CI 0.4-0.9) predicted invasive infection.
Discussion: CRE cases, following the new CRE case definition, had a 40% lower odds of invasive infections than that of the former. The cause of this shift is unclear as more data on antibiotic resistance profiles is needed to assess the definition’s overall performance. However, the impact of the new definition on invasive CRE infections is measurable and warrants further analysis.
A Contrastive Self-Supervised Learning scheme for beat tracking amenable to few-shot learning
Creators: name: Gagnere, Antonin
name: Peeters, Geoffroy
name: Essid, Slim
Publisher: name: arXiv
Year: 2024
Subjects: subject: Audio and Speech Processing (eess.AS)
subject: Sound (cs.SD)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: In this paper, we propose a novel Self-Supervised-Learning scheme to train rhythm analysis systems and instantiate it for few-shot beat tracking. Taking inspiration from the Contrastive Predictive Coding paradigm, we propose to train a Log-Mel-Spectrogram Transformer encoder to contrast observations at times separated by hypothesized beat intervals from those that are not. We do this without the knowledge of ground-truth tempo or beat positions, as we rely on the local maxima of a Predominant Local Pulse function, considered as a proxy for Tatum positions, to define candidate anchors, candidate positives (located at a distance of a power of two from the anchor) and negatives (remaining time positions). We show that a model pre-trained using this approach on the unlabeled FMA, MTT and MTG-Jamendo datasets can successfully be fine-tuned in the few-shot regime, i.e. with just a few annotated examples to get a competitive beat-tracking performance.
Modelos de dispersión larval para dos especies invasoras en el Golfo de México introducidas por plataformas petroleras
Creators: name: Hernández-Solis, Pablo Alberto
name: Simoes, Nuno
name: Mayorga-Adame, C. G.
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Larva
subject: Species
subject: Invasive species
subject: Introduced Species
subject: Dispersion
subject: Reef
subject: Coral reef
subject: Coral Reefs
subject: especies invasoras
subject: Golfo de México
subject: python
subject: Neopomacentrus cyanomos
subject: WoRMS: 218839
subject: Biology
subject: Marine biology
subject: Conservation
subject: Biodiversity conservation
subject: Nature conservation programme

description: Descubre más información sobre datos, investigaciones científicas, colecciones científicas y grupos de trabajo dedicados al estudio y conservación de la biodiversidad marina en https://www.bdmy.org.mx/

Discover more information about data, scientific research, scientific collections and working groups dedicated to the study and conservation of marine biodiversity at https://www.bdmy.org.mx/

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Examining Risk Behaviors of a School-Based Mental Health Program in Rural Georgia
Creators: name: Nava, Nancy
Publisher: name: Georgia State University
Year: 2018

description: INTRODUCTION: In the United States, approximately one out of five people experience a mental illness (CDC, 2018, SAMHSA, 2013) and half of mental health concerns start during adolescence (Belfer, 2008). Due to regular contact with children and adolescents, school-based mental health (SBMH) programs have emerged a promising solution to increase access to mental health services (Belfer, 2008).
AIM: This study aims to answer two questions. 1) Do participants in a school-based mental health program display a decrease in risk behaviors, as measured by the Child and Adolescent Needs and Strengths (CANS) assessment? 2) What intake measures predict a decrease in risk behavior at six months?
METHODS: This study is a preliminary analysis of an evaluation of a SBMH program being implemented in three rural school districts in the western part of Georgia. A Behavioral Health Assessment (BHA), the Columbia-Suicide Severity Scale (C-SSRS), and a CANS assessment are administered to students by school-based clinicians at intake. The CANS is followed up at six months. Primary research questions were answered using a non-parametric Wilcoxon-Sign Rank Test and a logistic regression.
RESULTS: The Wilcoxon-Sign Rank Test demonstrated a statistically significant reduction of student risk behavior. The final multi-logistic regression model included emotional lability, risk behaviors, emotional needs, and race. The logistic regression analysis indicated risk behavior, emotional needs, and emotional lability predictors of student risk reduction.
Conclusion: Findings from this study suggests that CANS can be utilized as an outcome measurement of risk behavior for student participating in a SBMH program. Furthermore, this study demonstrated that SBMH programs may be effective interventions for students in rural communities and adds to the growing body of literature which position SBMH programs as a promising intervention to increase access to mental health services for students in rural communities. Limitations of this study include possible therapist bias, lack of data, and generalizability of sample. Future research should continue to explore the impact of SBMH programs on student risk outcomes over time. In sum, this study provides preliminary evidence for the effectiveness of SBMH programs to meet student’s mental health needs and the utility of the CANS as an outcome measure.
Examining Correlates of Alcohol Related Condom-less Sex among Youth in Kampala, Uganda
Creators: name: Kumar, Sagar
Publisher: name: Georgia State University
Year: 2018

description: The purpose of this study is to examine the factors associated with alcohol related condom-less sex among youth living in the slums of Kampala, Uganda. Analyses are based on cross-sectional survey data, collected in 2014, of a convenience sample (n = 1134) of urban service-seeking youth participating in a Uganda Youth Development Link drop-in center. Logistic regression analyses were computed to determine the factors associated with intoxicated condom usage. The analytic sample consisted of only youth who responded to the dependent variable (n = 347), youth who reported not using a condom due while intoxicated and youth who reported using a condom while intoxicated. In the bivariate analysis, not using a condom while intoxicated was associated with being female (OR: 1.86; 95% CI: 1.21, 2.85), age of first drinking being between ages 13-16 (OR: 1.5; 95% CI: .79, 2.85), age of first time drunk being between ages 13-16 (OR: 2.88; 95% CI: 1.47, 5.67), binge drinking (OR: 3.64; 95% CI: 2.21, 5.98), rape (OR: 2.69; 95% CI: 1.64, 4.41), sex work (OR: 5.91; 95% CI: 3.09, 11.29), and being able to refuse sex when intoxicated (OR: 1.69; 95% CI: 1.10, 2.61). In the multivariable analysis, not using a condom while intoxicated was associated with being binge drinking (AOR: 2.97; 95% CI: 1.71, 5.17) and sex work (AOR: 3.48; 95% CI: 1.62, 7.49). The findings of this study emphasize many unmet needs of this vulnerable population. Strategies that specifically seek to address teenage alcohol prevention and delaying initial alcohol consumption may be particularly beneficial in this low-resource setting.
Exploring microRNA generated protein-protein interaction networks in silico
Creators: name: Konini, Silva
name: O'Brien, Jake
name: Peng, Chun
name: EJ Janse Van Rensburg
Publisher: name: F1000Research
Year: 2016

description: Two network topology-based algorithms are presented with the goal to discover pathways in protein-protein interaction networks, and to suggest new targets of miRNA.  The underlying idea in network based analysis is the discovery of cluster structures (of complexes and pathways) in protein-protein interaction networks.  These structures give information of biologically related proteins and their function. The key idea is that two proteins sharing higher topological similarities are likely interacting with each other and might belong to the same protein complex and cluster in the network.

We test two algorithms.  The first is to estimate similarities of the proteins in a network by using a Random Walk with Resistance (RWR). The second algorithm is to solve the Laplace Equation (LE), or a modified Laplace equation (LER) on the network, as an alternative to the  RWR.

Data on up and down regulated genes by microRNA hsa-miR-218-5p were obtained from the Peng lab. Protein-protein interaction networks were constructed on these by examining the environment of the genes in the STRING database of protein-protein interactions.

The structure of the networks was discovered with the RWR and LER algorithms, and visualized using Cystoscape. Protein clusters are discovered by joining two proteins in a network when there is a higher value of the Pearson Correlation Coefficient between their corresponding columns in the RWR probability matrix, or the LER Solution Matrix. The algorithms do not produce identical networks, but both show similar networks of biologically related clustered proteins. Clusters can be examined individually by RWR and LER algorithms to predict novel protein functions and reaction pathways.
Predicting Client Housing Outcomes from Georgia's Homeless Management Information System with Hierarchical Generalized Linear Modeling
Creators: name: Arce, Katherine
Publisher: name: Georgia State University
Year: 2018

description: During a given night in the United States, approximately 553,742 people experience homelessness, and 1.4 million people stay in an emergency shelter or transitional housing program each year. The aim of this study is to use a multilevel modeling approach to examine which client level and program level factors are associated with achieving permanent housing at program exit, as few studies in current literature assess both client and programmatic factor impact on housing outcomes simultaneously. Client level data from Georgia’s Homeless Management Information System for 8,756 clients enrolled in housing assistance programs was analyzed. The average age was 42.05; 71.96% of clients identified as Black or African American, 57.15% were male, 31.41% had mental illness, and 83.65% were in households without children. Data was analyzed using hierarchical generalized linear modeling to estimate the log odds of successful placement in permanent housing considering both client and program characteristics. Results show that individuals who were male, in households without children, and had mental illness were less likely to obtain permanent housing at program exit, regardless of which type of housing assistance program they were enrolled in. Clients enrolled in programs within the City of Atlanta were just as likely to obtain permanent housing at program exit as clients enrolled in programs outside of the city. Households with children were better able to secure permanent housing upon the conclusion of their housing assistance, controlling for program type and other client level factors. Clients who had been homeless for one year or longer prior to entering a housing program were less likely to obtain permanent housing at program exit. Findings indicate that more research on the barriers to housing for individuals in households without children is needed in order deliver appropriate and effective support services. This also implies that we need more support for single homeless men and those who have been homeless previously to help them achieve permanent housing.
Evaluating Hand Hygiene Compliance Among Healthcare Workers in a Specialized Pediatric Hospital
Creators: name: Monteiro, Abigail
Publisher: name: Georgia State University
Year: 2018

description: INTRODUCTION:  Hand hygiene(HH) is an important prevention measure for reducing healthcare-associated infections(HAIs), but adherence to HH compliance is suboptimal by healthcare workers(HCWs).
AIM: The aim of this study was to measure the adherence of HH compliance of HCWs and to identify hindrances in non-compliance in a specialized care pediatric hospital in the United States.
METHODS: An observational study of compliance of HH practices among HCWs using the direct observation method was conducted over a two-month period in 2017 at two campuses of a pediatric hospital, by one trained observer.  HH opportunities were defined by the World Health Organization’s “Five Moments for Hand Hygiene” and the Clean-in and Clean-out Campaign.
RESULTS:  A total of 2236 HH opportunities were observed during the two-month period with a compliance of 75%. HH compliance for both hospitals campuses differed upon entry and exit. Compliance did not vary significantly among hospital units and HCWs. Three barriers to HH compliance by HCWs appeared to be the most frequent; improper use of gloves, frequent entry and exit, and hands full with supplies.
DISCUSSION: The overall HH compliance among HCWs in the study was 76%, which exceeds the average reported compliance rate of 50%. Surveillance of HH is an important infection control policy that should be implemented by doing regular audits with feedback of results in an effort to encourage compliance.
Supplementary document for Improving the laser performance of ion beam sputtered dielectric thin films through the suppression of nanoscale defects by employing a xenon sputtering gas - 5953189.pdf
Creators: name: Mirkarimi, Paul
name: Harthcock, Colin
name: Qiu, S. Roger
name: Negres, Raluca
name: Guss, Gabriel
name: Voisin, Thomas
name: Hammons, Josh
name: Colla, Chris
name: Mason, Harris
name: Than, Anton
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Supplemental text
Reclutamiento de postlarvas de peces arrecifales en el parque de Xcaret: resultados preliminares
Creators: name: Ayala-Campo, Mitzi Yanin
name: Raigoza, Rodolfo
name: Valdez, Rafael
name: Simoes, Nuno
Publisher: name: Zenodo
Year: 2013
Subjects: subject: Reef
subject: Coral reef
subject: Coral Reefs
subject: Fish
subject: Fish behaviour
subject: Fish stock
subject: Fauna
subject: Marine fauna
subject: Ecological abundance
subject: Fish abundance in water bodies
subject: Environmental Monitoring
subject: Environmental Monitoring/statistics & numerical data
subject: Marine biology
subject: Marine ecosystem
subject: Marine biota
subject: Marine Biology
subject: Marine biodiversity
subject: Marine park
subject: Marine biology
subject: Marine organism
subject: Marine reserve
subject: Stegastes planifrons
subject: GBIF: 2398894
subject: Gobiosoma saucrum
subject: GBIF: 5208927
subject: Scorpaena inermis
subject: GBIF: 2334661
subject: Holocanthus ciliaris
subject: GBIF: 5211454
subject: Chaetodon capistratus
subject: GBIF: 2385548
subject: Stegastes diencaeus
subject: GBIF: 2398786
subject: Microspathodon chrysurus
subject: GBIF: 2398749

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Examining Education Level Correlation with Cognitive Function Among People with Alzheimer’s Disease
Creators: name: Dumas, Simone
Publisher: name: Georgia State University
Year: 2018

description: INTRODUCTION:  Alzheimer’s Disease (AD)is currently listed as the sixth leading cause of death among U.S. adults, killing more people than breast cancer and prostate cancer combined. While the number one risk factor for AD is increasing age, to date, little is known about preventive or protective factors of AD. Continued epidemiologic research that seeks to examine risk and protective factors, such as the role educational attainment plays in cognitive functioning among those with AD may offer important preventive insights.
AIM: The purpose of this study is to examine the correlation between education level and the cognition of persons with AD. An extensive data set was used that collects data from various locations, which will make for more reliable results. Ultimately, the hope is that interventions will be implemented to combat the detection bias due to later diagnosis of dementia (AD) in highly educated persons (Karp et al., 2002).
METHODS: The National Alzheimer’s Coordinating Centers (NACC) dataset from (2005-2017) was used to examine associations of cognitive function / impairment with variables related to sample demographics, health history, neuropsychological testing, risk behaviors, and education. Tests of correlation, ordinary least square, and logic regression tests were conducted to examine the relationship between cognitive impairment and educational attainment, along with possible co-variates.
RESULTS: There was a small positive correlation between subjects with an education and MMSE score, (r=0.2561, p < .05). For a one unit increase in the years of education was associated with a 0.341 (SD, 0.011) increase in MMSE Score. For a change in the education group 13-16 years and education group >16 years there is a 2.056 (SD, 0.090) and a 2.658 (SD, 0.097) unit change in MMSE score respectively. As the continuous education variable increased the AD diagnosis decreased by 0.067 (SD, 0.005). As education group 13-16 and >16 years changed from one group to the other AD diagnosis decreased (-0.488, SD 0.040 and -0.629, SD 0.043).
DISCUSSION: Results from this study may be theoretically explained-that higher educational attainment may be associated with a fundamentally higher cognitive reserve among older adults who have cognitive disorders. The lower likelihood of AD pathology may be associated with higher functioning or potentially a lower diagnosis of AD. The role education plays among older adults with cognitive disorder diagnoses appears to be linked, yet this relationship, with AD pathology in particular, warrants further research attention.
CAREX Toolbox Handout 1 - CAREX Key Steps
Creators: name: Febria, Catherine M.
name: Hogsden, Kristy
name: Devlin, Hayley S.
name: Collins, Katie
name: Goeller, Brandon C.
name: Harding, Jon S.
name: McIntosh, Angus R.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310304
subject: Freshwater ecology

description: Through the CAREX project, we have tested a series of
practical tools, and developed solutions and approaches to address aquatic
weed, sediment, and nutrient management issues in agricultural waterways in
lowland Canterbury.

We have developed a set of steps and toolboxes, underpinned
by science, which can be applied by farmers, landowners and stakeholders to
facilitate rehabilitation and improve agricultural waterway health.This handout is the first in a series, which outlines the
CAREX key steps and the tools we have tested to improve waterway health.

Suggested citation: Febria, C.M., Hogsden,
K.L., Devlin, H.S., Collins, K.E., Goeller, B.C, Harding, J.S., and A.M. McIntosh.
2018. CAREX Key Steps, CAREX Toolbox Handout 1, University of Canterbury,
Christchurch.
A predator has nonconsumptive effects on different life-history stages of a prey
Creators: name: Ellrich, Julius A.
name: Scrosati, Ricardo A.
name: Bertolini, Camilla
name: Molis, Markus
Publisher: name: F1000Research
Year: 2016

description: This presentation was given at the Atlantic Canada Coastal & Estuarine Science Society (ACCESS) Conference at the University of Prince Edward Island in Charlottetown, PEI, Canada in May 2016. It is based on the article

Ellrich, J. A., R. A. Scrosati, C. Bertolini & M. Molis (2016) A predator has nonconsumptive effects on different life-history stages of a prey. Marine Biology 163:5 DOI 10.1007/s00227-015-2778-6 (link)
3D-structure biocuration: a wealth of information in UniProtKB/Swiss-Prot
Creators: name: Hinz, Ursula
name: UniProt Consortium
Publisher: name: F1000Research
Year: 2016

description: Protein 3D-structures provide essential information about protein function in health and disease.  UniProtKB/Swiss-Prot biocurators make use of this wealth of data, combining 3D-structure data with information derived from the scientific literature to verify protein function and mode of action, validate enzyme active sites, identify physiologically relevant ligand binding sites and post-translational modifications, and interactions between proteins, or proteins and nucleic acids. This information is shown in a structured format in the UniProtKB/Swiss-Prot entries to facilitate retrieval of specific pieces of information: protein function and subunit structure, cofactor requirements, the role of specific residues, domains and regions, post-translational modifications, membrane topoplogy, etc., with evidence tags to indicate the sources of the information. Information from well-characterized proteins is then propagated to close family members. As a result, out of roughly 550’000 UniProtKB/Swiss-Prot entries, ca. 88’000 contain information about metal-binding sites, 137’000 contain information about the binding sites for nucleotides or other small organic ligands and about 95’000 contain active site annotations, to cite only the most abundant types of annotation.

In UniProtKB, cross-references to PDB and PDBSum facilitate access to experimental 3D-structures, while cross-references to Swiss Model repository (SMR) and Protein Model Portal facilitate access to theoretical models.

In January 2016, UniProtKB/Swiss-Prot contained 123’700 cross-references to PDB, corresponding to over 22’900 entries, mostly from model organisms. Over 25% (5’700) of the 20’200 human entries have a cross-reference to PDB, and the majority of these have at least one matching literature citation. The situation is similar for other model organisms.
Examining the Association Between Well Child Care and Developmental and Behavioral Health Conditions in Children
Creators: name: Meyn, Alison
Publisher: name: Georgia State University
Year: 2018

description: Background: Well child care visits (WCC) are critical preventive care visits that start at infancy. Currently, little is known about the association between WCC and parent report of developmental and behavioral health conditions in children. The purpose of this research was to examine if WCC contributes to developmental/behavioral health conditions reported by parents. 

Methods: The 2016 National Health Interview Survey data were used for this research. Weighted estimates were calculated to assess the relationship between the receipt of WCC (yes or no response to receiving WCC in past 12 months) and presence of developmental/behavioral conditions; a Pearson’s chi square was used to determine bivariate associations between characteristics and WCC, followed by multivariable logistic regression to adjust for child sex, child age, healthcare access of parents, parent education level and parent income level. 

Results: Among 2,453 children 3 years and younger 91.04% of these children had received WCC in the past 12 months. The weighted percent of children with any developmental/behavioral conditions was 7.78% in those receiving WCC and 4.62% in children not receiving WCC. Bivariate associations determined that the statistically significant characteristics for determining whether a child receives WCC are: the child’s race/ethnicity, the number of office visits to their primary care (which are a combination of WCC and sick child visits), parent education level, and combined family income level. The logistic regression model evaluating developmental and behavioral conditions adjusted for these variables that were statistically significant. In the adjusted model it was found that the number of office visits and parent education level were statistically significant in the detection of developmental and behavioral health conditions.

Conclusion: The number of office visits (which include WCC) are important preventive clinical services for identifying developmental/behavioral conditions in young children. Parent education level is another significant factor that determines receipt of WCC and detection of developmental/behavioral conditions. By understanding the factors associated with WCC, targeted interventions can be developed to increase identification of developmental/behavioral conditions.
Trends in Prediabetes and Associated Comorbid Conditions in Adolescents Aged 12 to 19 Years, Between 2003 and 2014.
Creators: name: Dias, Taylor
Publisher: name: Georgia State University
Year: 2018

description: NTRODUCTION:  Understanding of the trends in Pre-Diabetes (PD), a reversible condition and precursor/risk factor for Type II Diabetes Mellitus (T2DM), among adolescents may help to develop robust public health initiatives for slowing the epidemic of T2DM and its associated comorbidities. Currently, published research only investigates only the prevalence of T2DM and T1DM in the adolescent population with no focus on PD. We have  the following three hypotheses: the prevalence of PD will be increasing during the study period, the prevalence of both comorbid conditions will be increasing in prevalence, there association of PD with each of the comorbid conditions will grow stronger over the study period.
 
AIM:  Our aim is to determine the prevalence of PD and associated comorbid conditions in the adolescent population. Slowing the progress of this epidemic is crucial for improving the long-term quality of life for high-risk populations, and can prevent adolescents from having expensive chronic conditions as they progress to adulthood.
 
 
METHODS:  Data from NHANES  2003  - 2014 was used conduct analyses. The study sample was restricted to include only participants aged 12 to 19 years, and participants who were selected for lab work as this is the smallest  subset of the participants for each year. Proper sample weights, according to sampling methodology were used, to obtain prevalence value for each year, as well as to obtain correlation values in SAS 9.4.
 
RESULTS & Discussion:   Contrary to our hypotheses there was an observed decrease in prevalence of PD and LDL category as well as average LDL reading during the study period. Additionally, the associations of PD and the comorbid were weak, and showed no trend during the study period. However, the prevalence of overweightness/obesity was increasing during the study period, and mean BMI was also increasing during the study period.
Validation of Viral Inactivation by a Heat Inactivation Effluent Discharge System in a High Containment Research Laboratory Using Viral Surrogates Phi6 and MS2
Creators: name: Kshatri, Michael
Publisher: name: Georgia State University
Year: 2018

description: The 2014 outbreak of Ebola increased the need for many types of research involving work with infectious Ebola virus. Due to the high mortality rate and limited treatment options, Ebola can only be handled at the highest level of laboratory containment, biosafety level (BSL) 4. One of the requirements of a BSL4 laboratory is that liquids from sinks, drains, and other liquid disposal systems cannot be discharged directly into the sanitary sewer. One option for such laboratories is an effluent discharge system (EDS) where effluent is held in a tank at high temperature for a period of time to inactivate microbes before being disposed of in the sanitary sewer. These systems must be validated to ensure they can inactivate viruses like Ebola before disposal. Surrogate viruses Phi6 and MS2 were used to serve as models for the behavior of human viruses. These viruses were used to determine effective time and temperature combinations for an EDS. In this project, Phi6 and MS2 were suspended in water with protein added and were exposed to temperatures of 70oC and 90oC at time points 0 seconds, 30 seconds, 1 minute, 5 minutes, 6 minutes, 7 minutes, and 10 minutes to mimic an EDS. An inactivation curve was developed using the double agar layer technique to determine different log reductions over time so that protocols may be established for the EDS. Based on the results, it would be recommended to run the EDS at these temperatures for 10 minutes or longer to ensure complete inactivation.
CAREX Toolbox Handout 1 - CAREX Key Steps
Creators: name: Febria, Catherine M.
name: Hogsden, Kristy
name: Devlin, Hayley S.
name: Collins, Katie
name: Goeller, Brandon C.
name: Harding, Jon S.
name: McIntosh, Angus
Publisher: name: figshare
Year: 2018
Subjects: classificationCode: 310304
subject: Freshwater ecology

description: Through the CAREX project, we have tested a series of
practical tools, and developed solutions and approaches to address aquatic
weed, sediment, and nutrient management issues in agricultural waterways in
lowland Canterbury.

We have developed a set of steps and toolboxes, underpinned
by science, which can be applied by farmers, landowners and stakeholders to
facilitate rehabilitation and improve agricultural waterway health.This handout is the first in a series, which outlines the
CAREX key steps and the tools we have tested to improve waterway health.

Suggested citation: Febria, C.M., Hogsden,
K.L., Devlin, H.S., Collins, K.E., Goeller, B.C, Harding, J.S., and A.M. McIntosh.
2018. CAREX Key Steps, CAREX Toolbox Handout 1, University of Canterbury,
Christchurch.