cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
HIGH PERFORMANCE COMPUTATIONAL INTELLIGENCE FOR COHERENT DIFFRACTION DATA ANALYSIS AND IMAGING
Creators: name: COLOMBO, ALESSANDRO
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: Coherent Diffraction Imaging (CDI) is a lens-less technique that allows imaging of matter at a spatial resolution not limited by lens aberrations. This technique exploits the measured diffraction pattern of a coherent beam scattered by periodic and non?periodic objects to retrieve spatial information. The diffracted intensity, for weak?scattering objects, is proportional to the modulus of the Fourier Transform of the object density distribution. Any phase information, needed to retrieve the sample density, has to be retrieved by means of suitable algorithms. This work presents a new approach based on Computational Intelligence, in particular on Genetic Algorithms, to face the phase retrieval problem. This new approach, called Memetic Phase Retrieval, is described, along with its implementation specifically designed and optimized for High Performance Computing hardware. Tests on both simulated and experimental data are performed, showing a remarkable performance improvement with respect to standard algorithms. Memetic Phase Retrieval proves to be a new powerful tool for the study of matter via CDI. Moreover, it represents a novelty, laying the foundations for a more extensive use of Computational Intelligence in the field of CDI and opening new perspectives in those applications in which reliable phase retrieval is necessary.
On the Impact of Solvation on a Au/TiO2 Nanocatalyst in Contact with Water
Creators: name: Camellone, Matteo Farnesi
name: Marx, Dominik
Publisher: name: arXiv
Year: 2013
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Water, the ubiquitous solvent, is also prominent in forming liquid solid interfaces with catalytically active surfaces, in particular with promoted oxides. We study the complex interface of a gold nanocatalyst, pinned by an F center on titania support, and water. The ab initio simulations uncover the microscopic details of solvent-induced charge rearrangements at the metal particle. Water is found to stabilize charge states differently from the gas phase as a result of structure specific charge transfer from to the solvent, thus altering surface reactivity. The metal cluster is shown to feature both cationic and anionic solvation, depending on fluctuation and polarization effects in the liquid, which creates novel active sites. These observations open up an avenue toward solvent engineering in liquid-phase heterogeneous catalysis.
LOCAL DISORDER IN THE STRUCTURE OF BA(TI,CE)O3 PEROVSKITE BY MEANS OF POWDER DIFFRACTION AND TOTAL SCATTERING. EFFECT OF TEMPERATURE, DOPING CONCENTRATION AND GRAIN SIZE.
Creators: name: CONFALONIERI, GIORGIA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Nowadays BaTiO3 is considered as one of the most relevant environmental-friend ferroelectric and, thank to the chemical substitutions at the Ba2+ and/or Ti4+ sites, its properties are usually tailor to meet a big variety of devices and performance requirements. A classical example is the solid solution BaTi1-xMIVxO3, where M could be Sn, Zr, Hf, Ce etc., whose ferroelectric behavior shows an almost continuous variation with composition. The study of these compounds is then essential to improve their characteristics and make their suitable in more applications. Considering that their properties are deeply linked to the structure and especially to structural defects, average and local structural analyses are essential to better understand the origins of different polar behaviours and to have a real control on these materials. Despite this need, only BaTi1-xZrxO3 (BTZ) system, which is one of the most popular dielectrics used in multilayer ceramic capacitors, has been investigated in some detail. Although the similarity to BTZ suggests that BaTi1-xCexO3 (BTC) may be promising as lead free actuator materials, studies on this solid solution are almost limited. Thus in this research the BTC solid solution has been structurally investigated in order to provide knowledge lacks. Different ceramic samples with different doping amounts and different polar behaviours (from normal ferroelecric to relaxor via diffuse phase transition) have been investigated at different temperatures. In addition, taking into account the current tendency in miniaturized devices required in microelectronics, also chemical equivalent nano powders have been considered to explore not only doping effects, but also that of size. Pair Distribution Function (PDF) with different type of approaches (as carbox, biphasic and so on) has been employed coupled with TEM analysis and Raman spectroscopy. A complete description of that BaTi1-xCexO3 materials is given underlining links between polar behaviours, temperature, doping and size effects.
A Feminist Perspective on Food-Related Patents: On Messiness, Nature and the Social
Creators: name: Lai, Jessica
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2025
Subjects: classificationCode: 4804
subject: Law in context
classificationCode: 4803
subject: International and comparative law
classificationCode: 4806
subject: Private law and civil obligations
classificationCode: 48
subject: Law and legal studies

description: No description supplied
title: Business English
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Данное учебное пособие предназначено для студентов всех специальностей всех форм обучения ЧОУ ВПО «Южно-Уральский институт управления и экономики». Пособие содержит основные сведения об особенностях составления и оформления официальных, деловых и дружеских писем на английском языке, также в пособии содержится информация о правилах проведения деловых переговоров и телефонных разговоров. Пособие состоит из 14 тем, соответствующих рабочей программе дисциплины «Деловые переговоры на английском языке». Освоение материала данного учебного пособия позволяет полностью подготовиться к зачету или экзамену по данной дисциплине.
Proton Electrodynamics in Liquid Water
Creators: name: Volkov, A. A.
name: Artemov, V. G.
name: Pronin, A. V.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: The dielectric spectrum of liquid water, $10^{4} - 10^{11}$ Hz, is interpreted in terms of diffusion of charges, formed as a result of self-ionization of H$_{2}$O molecules. This approach explains the Debye relaxation and the dc conductivity as two manifestations of this diffusion. The Debye relaxation is due to the charge diffusion with a fast recombination rate, $1/τ_{2}$, while the dc conductivity is a manifestation of the diffusion with a much slower recombination rate, $1/τ_{1}$. Applying a simple model based on Brownian-like diffusion, we find $τ_{2} \simeq 10^{-11}$ s and $τ_{1} \simeq 10^{-6}$ s, and the concentrations of the charge carriers, involved in each of the two processes, $N_{2} \simeq 5 \times 10^{26}$ m$^{-3}$ and $N_{1} \simeq 10^{14}$ m$^{-3}$. Further, we relate $N_{2}$ and $N_{1}$ to the total concentration of H$_{3}$O$^{+}$--OH$^{-}$ pairs and to the pH index, respectively, and find the lifetime of a single water molecule, $τ_{0} \simeq 10^{-9}$ s. Finally, we show that the high permittivity of water results mostly from flickering of separated charges, rather than from reorientations of intact molecular dipoles.
description: 5 pages
DOSAGGIO DIRETTO DELLA RENINA CON METODICA CHEMILUMINOMETRICA:CONFRONTO CON LA TECNICA ENZIMATICA ED UTILIZZO NELLO SCREENINGDELL�IPERALDOSTERONISMO PRIMITIVO
Creators: name: LONATI, CHIARA
Publisher: name: Universit� degli Studi di Milano
Year: 2013

description: Background: Direct plasma renin concentration determined with chemiluminometric immunoassay (CliR, mU/l) is progressively replacing plasma renin activity (PRA, ng/ml/h) for clinical use but the conversion factors (CF) between the two methods are still unsettled as well as their influence on the calculation of aldosterone/renin ratio (ARRD and ARRP). Methods: CliR, PRA and aldosterone (A, ng/dl) were measured in plasma samples collected in the supine position (S) and after 1 hour of active standing (AS) in 88 patients with essential hypertension (EH) on treatment with various antihypertensive drugs including ACEIs and ARBs. The same determinations were made in S in 10 patients with primary hyperaldosteronism (PHA) due to adrenal adenoma histologically confirmed. Results: In EH the median values (range) of CliR in S and AS were 18 (2-255) and 28 (4-471) respectively, the corresponding values of PRA being 0.6 (0.2-11.2) and 1.3 (0.3-16.0). Supine and upright CliR and PRA were highly correlated with a Spearman rs of 0.85 and 0.84 respectively. The linear non parametric Passing-Bablok regression on all logarithmic values in S and AS gave a slope of 1.01, an intercept of 3.2 and a CF of 24.6 between PRA and CliR on the natural scale. In EH the median values (range) of A in S and AS were 7.8 (0.3-31) and 18.4 (2.3-60). In PHA patients the median values of CliR, PRA and A in S were 0.8 (0.2-10.2), 0.1 (0.1-0.6) and 36.8 (11.8-122). In EH the median values of ARRD in S and AS were 0.4 (0.01-3) and 0.5 (0.02-7.8) respectively, the corresponding values of ARRP being 12 (0-71) and 13 (0-80). ARRD and ARRP were strongly correlated, with an rs of 0.88 and 0.92 in S and AS respectively. The regression analysis of all logarithmic values in S and AS showed a slope of 1.12, an intercept of -3.53 and a CF of 0.03 between ARRP and ARRD on the natural scale. In PHA patients the median value of ARRD in S was 34 (2.8-244) and that of ARRP 298 (48-1222). Assuming as cut-off values of normalcy those recommended by guidelines (Funder et al, JCEM 2008; 93: 3266) i.e. 30 for ARRP and 3.7 for ARRD, there were 13 false positives in S and 18 in AS for ARRP with a specificity of 0.85 (CI95% 0.76-0.92) and of 0.78 (0.68-0.87) respectively while with ARRD there were only 0 and 4 false positives with a specificity of 1 (0.96-1) and of 0.95 (0.88-0.99). Conclusions: In EH on treatment CliR and PRA, as well as ARRD and ARRP, are highly correlated. However, using the conventional cut-off values, for the diagnosis of PHA the specificity of ARRD is better than that of ARRP. Moreover the specificity of ARRD appears to be minimally affected by antihypertensive treatment.
HETEROHELICENES AS APPEALING CHIRAL SYSTEMS: INNOVATIVE METHODOLOGIES FOR THEIR PREPARATION ALSO IN ENANTIOMERICALLY PURE FORM
Creators: name: PELLICCIOLI, VALENTINA
Publisher: name: Universit� degli Studi di Milano
Year: 2021

description: Helicenes are ortho-annulated polycyclic aromatic or heteroaromatic compounds, endowed with inherent chirality owing to the helical shape of their ?-conjugated system. Carbohelicenes only include benzene rings in their structure, while in heterohelicenes one or more heterocycles are present. Interestingly, the introduction of heteroatoms into the fused polycyclic frameworks adds remarkable changes to the electronic structures of helicenes, and additional chemical and physical properties. Their unique structural features and physicochemical properties have stimulated manifold studies in several fields, including optoelectronics, material science, asymmetric catalysis, and chiral recognition. Many of these applications require the use of enantiomerically pure helicenes, although the resolution of racemates by means of analytical methods as well as the separation of diastereomers still remain the most common ways to obtain non-racemic helicenes, whose peculiar geometry makes them extremely difficult targets for stereoselective synthesis. This Ph.D. thesis was intended to provide a meaningful contribution in the development of innovative and versatile syntheses of heterohelicenes, also in enantiopure form, and has focused on the following main goals: 1. Study of methodologies for the synthesis of functionalised tetrathia[7]helicenes (7-THs). 2. Synthesis of different classes of thiahelicenes through methodologies set up for the preparation of 7-THs. 3. Enantioselective synthesis of thia[5]helicenes via Au-catalysed alkyne hydroarylation. In the course of this thesis, a sub-topic has also been developed: 4. Functionalisation of benzo[1,2-b:4,3-b']dithiophenes by Suzuki reactions in Deep Eutectic Solvents (DESs).
title: Владельческая защита в системе вещно-правовых способов защиты права собственности
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: В монографии рассматриваются проблемы вещно-правовых способов защиты права собственности. Особое внимание уделено владельческой защите как развивающемуся институту гражданского права. В работе проведено сравнение владельческой защиты с виндикационным и негаторным исками. На основе анализа применения института владельческой защиты в иностранных правовых системах, проекта изменений Гражданского кодекса РФ и сложившейся судебной практики сформулированы вводы и предложения по совершенствованию законодательства. Книга адресована для научных сотрудников, преподавателей, аспирантов, магистрантов, обучающихся юридических направлений, а также для широкого круга читателей.
Novel multi-omic algorithms to predict treatment response in prostate cancer
Creators: name: Panja, Sukanya
Publisher: name: No Publisher Supplied
Year: 2022

description: Therapeutic resistance is a critical challenge in prostate cancer management. The lack of genome-wide computational tools to identify patients at risk of treatment resistance hampers personalized therapeutic planning, which could potentially delay disease progression, eliminate harmful side effects. and improve outcomes. To address this problem, I have developed two novel computational algorithms: (i) Epi2GenR, that integrates DNA methylation and mRNA gene expression patient profiles to identify markers associated with response to first-generation androgen deprivation therapy in prostate cancer; and (ii) TR-2-PATH, that integrates transcriptional regulatory programs and molecular pathways to identify markers associated with response to second generation androgen-deprivation (Enzalutamide) in castration resistant prostate cancer (CRPC) patients. Epi2GenR uncovered a panel of 5 differentially expressed and methylated sites, which could accurately predict primary resistance to first-generation androgen-deprivation therapy (log-rank p = 0.019), while TR-2-PATH uncovered MYC pathway and its upstream transcriptional regulatory program, NME2, to be significantly associated with response to Enzalutamide in CRPC patients (log-rank p = 0.0035). We anticipate that these discoveries can be utilized in the clinic to identify patients at risk of treatment resistance, which paves the road to personalized therapeutic advice and improved outcomes for patients with prostate cancer.
DISSECTING THE TRANSFORMATION PROCESS IN MAMMARY STEM CELLS
Creators: name: PASI, CRISTINA ELISABETTA
Publisher: name: Universit� degli Studi di Milano
Year: 2011

description: Stem Cells (SCs) may play a critical role in cancer development, yet the direct demonstration is still lacking. The characterization of mechanisms that sustain and regulate Cancer Stem Cells (CSCs) may help elucidating their role in tumors. Using a MMTV-ErbB2 breast cancer mouse-model, we had previously shown that CSCs, through multiple rounds of symmetric divisions and extended self-renewal, drive tumor growth and the expansion of the CSC pool. Critical for this property is the lack of functional p53, that drives CSCs to symmetric divisions. Here we show that symmetric divisions and extended self-renewal in CSCs are due to the activation of c-myc as direct consequence of the loss of functional p53. In particular, c-myc is upregulated in transformed and p53-/- immortalized SCs, and enforced expression of c-myc in normal mammary SCs induces symmetric divisions and extended self-renewal, but does not transform. We show that mammary progenitors expressing c-myc acquire in vitro self-renewal properties (mammosphere formation and expansion) and in vivo regenerative potential (formation of normal mammary gland upon transplantation). Our data suggest that c-myc is critical for the maintenance of CSCs in ErbB2-mammary tumors and their aberrant self-renewing properties. This is achieved through its binary effect on CSCs (induction of symmetric divisions) and progenitors (reprogramming into CSCs). Recent studies demonstrate that c-myc over-expression in epithelial tissues induces an abnormal transcriptional pattern, similar to that of embryonic SCs, and that the same is activated in epithelial cancers and CSCs. This suggests that c-myc may be a general regulator of CSCs and their altered self-renewing properties.
Realization of stripes and slabs in two and three dimensions
Creators: name: Giuliani, Alessandro
name: Lieb, Elliott H.
name: Seiringer, Robert
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We consider Ising models in two and three dimensions with nearest neighbor ferromagnetic interactions and long range, power law decaying, antiferromagnetic interactions. If the strength of the ferromagnetic coupling J is larger than a critical value J_c, then the ground state is homogeneous and ferromagnetic. As the critical value is approached from smaller values of J, it is believed that the ground state consists of a periodic array of stripes (d=2) or slabs (d=3), all of the same size and alternating magnetization. Here we prove rigorously that the ground state energy per site converges to that of the optimal periodic striped/slabbed state, in the limit that J tends to the ferromagnetic transition point. While this theorem does not prove rigorously that the ground state is precisely striped/slabbed, it does prove that in any suitably large box the ground state is striped/slabbed with high probability.
description: 4 pages, 1 figure
title: Гидравлика
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Учебное пособие соответствует учебной программе по дисциплине «Гидравлика» ОУ ВО «Южно-Уральский институт управления и экономики». В пособии изложены основные законы покоящейся и движущейся жидкости, а также краткое устройство и принцип действия гидромашин. Учебное пособие состоит из двух частей: в первой рассматриваются основы гидравлики, во второй — основы гидропривода. Предназначено для студентов, обучающихся по направлению 23.03.01 «Технология транспортных процессов», является единым для всех форм обучения.
DEXMEDETOMIDINE VS. XYLAZINE: EFFECTS ON BEHAVIOUR AND PLASMA CONCENTRATIONS OF CORTISOL AND SUBSTANCE P IN CALVES UNDERGOING TRUE AND SHAM DISBUDDING
Creators: name: LOCATELLI, VALENTINA
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: Summary Disbudding is a routine painful procedures carried out on cattle to facilitate management (Gottardo et al. 2011, Duffield 2008, Laine et al. 2007, Stafford et al. 2005 e 2003, Marshall, 1977; Vowles, 1976). To measure the pain-induced distress caused by dehorning or disbudding plasma concentration of cortisol have been used more frequently than any other parameter (Boandl et al., 1989; Taschke and Folsch, 1993; Wohlt et al., 1994; Cooper et al., 1995; Morisse et al., 1995; Petrie et al., 1996; Sylvester et al., 1998; McMeekan et al., 1997, 1998; Graf and Senn, 1999; Grondahl-Nielsen et al., 1999; Sutherland et al., 2002), but Stilwell et al. in 2010 confirm that cortisol is not a good indicator of pain. Substance P is a neurotransmitter of pain used for the first time in cattle in 2008 by Coetzee et al. who found that substance P is a better indicator of pain than cortisol in calves after castration or simulated castration. On these basis we hypothesized that SP could potentially be a more specific measure of pain in cattle undergoing disbudding than would the plasma cortisol response, but the methods to measure its concentration in cattle plasma is still to set up, so we are improving it. We studied the effects of true and simulated disbudding on plasma concentration of cortisol in calves undergoing 2 different alpha2-agonists: xylazine and dexmedetomidine. Plasma cortisol concentration has not been an useful method to compare the analgesic features of the 2 alpha 2agonists xylazine and dexmedetomidine. In fact they both act on the plasma concentration of cortisol, increasing it because of their effects on baroreflex and on muscles. In Veterinary Medicine dexmedetomidine is registered only for its utilization on cats and dogs and it is appreciated for its minimal side effects on the respiratory tract, for its remarkable sedative and anxiolytic properties and for the possibility it can be administered by continuous infusion. The utilization of dexmedetomidine in cattle has never been researched right now
Pap_01_Semantic-Segmentation-of-High-Resolution-Satellite-images.pdf
Creators: name: Aithal, Bharath
name: dey, Madhumita
Publisher: name: figshare
Year: 2022
Subjects: Land use and environmental planning
Regional analysis and development
Urban analysis and development
Urban and regional planning not elsewhere classified
Urban informatics

description: High-dimensional geospatial data visualization has gained much importance in recent decades. But to analyze it, traditional technologies used in machine learning are not convincing enough, and thus to switch to a subdomain of machine learning called deep learning that has gained popularity because of its accuracy and high dimensional data analysis power. Its convergence with geospatial data analytics shall prove to be a boon to the researchers working in the domain of geospatial data. Though Geospatial information is mostly used in the global mapping process of satellite images. The heterogeneity of the data makes it infeasible for global scale mapping. Therefore, to handle this problem is to partition the entire world into several regions. Semantic segmentation is one such technique and is widely used for information extraction from satellite images. The technique essentially refers to segmenting the input image pixel into multiple semantic regions, that is, to assign a semantic pixel category to each pixel in the image. In this context, we propose a semantic segmentation method that utilizes the spatial information of the high-resolution remote sensing data. The aim is to leverage the openly available data to automatically generate a larger training dataset with more variability and can be used to build more accurate deep learning models. The proposed automatic extraction can capture context information and its symmetric expanding path enables precise localization. The most characteristic property is the upsampling part that has feature channels that allow propagation of context information to higher resolution layers and makes the expansive path roughly symmetric to the contracting path yielding a U-shaped architecture. Mean IOU (mIOU) is used as the performance matrix and results yield 0.79. Since the model is trained on a small training dataset, that makes the deep learning model prone to overfitting. Training on such a small set of images makes this a challenging task. Validation dataset metrics obtained after training will signify the model’s general adaptability on other datasets of other segmentation tasks
Optimized controlled Z gates for two superconducting qubits coupled through a resonator
Creators: name: Egger, D. J.
name: Wilhelm, F. K.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Superconducting qubits are a promising candidate for building a quantum computer. A continued challenge for fast yet accurate gates to minimize the effects of decoherence. Here we apply numerical methods to design fast entangling gates, specifically the controlled Z, in an architecture where two qubits are coupled via a resonator. We find that the gates can be sped up by a factor of two and reach any target fidelity. We also discuss how systematic errors arising from experimental conditions affect the pulses and how to remedy them, providing a strategy for the experimental implementation of our results. We discuss the shape of the pulses, their spectrum and symmetry.
Ovarian volume throughout life: a validated normative model
Creators: name: Kelsey, Thomas W.
name: Dodwell, Sarah K.
name: Wilkinson, A. Graham
name: Greve, Tine
name: Andersen, Claus Y.
name: Anderson, Richard A.
name: Wallace, W. Hamish B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Biological sciences
subject: FOS: Computer and information sciences
subject: G.1.2
subject: 92B05

description: The measurement of ovarian volume has been shown to be a useful indirect indicator of the ovarian reserve in women of reproductive age, in the diagnosis and management of a number of disorders of puberty and adult reproductive function, and is under investigation as a screening tool for ovarian cancer. To date there is no normative model of ovarian volume throughout life. By searching the published literature for ovarian volume in healthy females, and using our own data from multiple sources (combined n = 59,994) we have generated and robustly validated the first model of ovarian volume from conception to 82 years of age. This model shows that 69% of the variation in ovarian volume is due to age alone. We have shown that in the average case ovarian volume rises from 0.7 mL (95% CI 0.4 -- 1.1 mL) at 2 years of age to a peak of 7.7 mL (95% CI 6.5 -- 9.2 mL) at 20 years of age with a subsequent decline to about 2.8mL (95% CI 2.7 -- 2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis and management of a number of diverse gynaecological and reproductive conditions in females from birth to menopause and beyond.
description: 14 pages, 7 figures
ALPINE PROTECTED AREAS IN A CHANGING CLIMATE. A GEOGRAPHY OF SCIENCE PERSPECTIVE
Creators: name: TOLUSSO, EMILIANO
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: cience, despite being one of the most universal social endeavours of mankind, is not equally practiced everywhere in the world. Science maintain different roles in different protected areas. As a result, there are regions where scientific information is created more frequently. At the same time, different places are following different scientific paths. It is no surprise that Yellowstone National Park is involved in the creation and circulation of studies on wildlife and the effects of climate change, and produce scientific research more than any other protected area in the world. Conversely, it is highly surprising that climate change science can be completely excluded by the research activities carried in some protected areas in the Alps. International monitoring initiatives, in the meantime, are promoting the circulation of science beyond borders, and providing us with data and powerful images of the effects of climate change from all parts of the world. It is normal, in our everyday scientific landscape, to see proofs of new pioneer species settling in mountaintops in the Tien Shan Range, while living at the foothills of the Alps. We are accustomed to seeing pictures of glacier melting in National Parks in the Andean Cordillera while we spend time monitoring the upward and northward distributional shift of butterflies species in the Rocky Mountains. However, we seldom inquire in the precise geography of the distribution of scientific research. Which protected areas in which regions are producing more research? What are the factors that influence distribution? This work aims at filling exactly this gap, with a particular focus on the Alpine range.
Interference of Topologically Protected Edge States in Silicene Nanoribbons
Creators: name: Ezawa, Motohiko
name: Nagaosa, Naoto
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Silicene is a two-dimensional quantum spin-Hall insulator. We study the edge channels of silicene nanoribbons from the viewpoint of the topological protection and the interference between the two edges. It is found that the behaviors of the helical edge channels (HECs) are completely different between the armchair and zigzag edges. The penetration depths $ξ$ of the HEC is antiproportional to the spin-orbit gap for the armchair edge $ξ_{\rm arm} \sim \hbar v_\text{F}/ Δ$ ($v_\text{F}$: the Fermi velocity, $Δ$: the gap due to the spin-orbit interaction), while it remains as short as the lattice constant for the zigzag edge. Zero-energy states disappear in armchair nanoribbons due to an interference of two edge states, while they remains in zigzag nanoribbons even if the width $W$ is quite narrow. The gap $δ$ of HECs behaves as $δ\sim \hbar v_\text{F}/W$ for $Δ=0$, and as $δ\sim Δ\exp[- W/ξ_{\rm arm}]$ for $Δ\not=0$ for armchair nanoribbons, while it remains essentially zero irrespectively of $Δ$ for zigzag nanoribbons.
description: 5 pages, 6 figures
Murals, territorial stigma and youth perspectives
Creators: name: Craig, Peggy Jean
Publisher: name: No Publisher Supplied
Year: 2022

description: This study examines territorial stigma and its impact on youth residents in two predominantly Black and Brown stigmatized neighborhoods in North Philadelphia, Pennsylvania and Camden, New Jersey. I hypothesize that a saturation of neighborhood murals mitigates territorial stigma through the presentation of a more positive alternative narrative about place. Using a Community-based Participatory Research Method (CBPR) called Participatory Photo-Mapping (PPM), I engaged twenty-four neighborhood youth as co-researchers to investigate 1) the influence of murals on youth perspectives of place and their own identity; and more broadly, 2) the strategies youth use to cope with territorial stigma. I adapted the PPM method to generate co-created data from photography projects and youth-led walking tours, and then engaged my co-researchers in data analysis exercises and community presentations. I find that 1) murals have a weak positive influence on how youth residents see themselves and their neighborhoods; 2) youth negotiate territorial stigma in multiple discrete and nuanced ways including practicing variations of submission or resistance to stigma; and 3) the presence and proximity of gentrification, perceived as a threat to home, intensifies and concretizes the negative effects of territorial stigma on youth residents by fracturing and weakening a collective sense of place. In fact, the powerful negative impact of gentrification appears to overwhelm the more modest positive influence of mural arts in countering territorial stigma. PPM allowed for this last finding to emerge, as I had not anticipated any role for gentrification in my research design. I discuss the implications of what I call stigmatized-spatial identity resulting from the internalization of territorial stigma beyond feelings of spatial anguish, and conclude with suggestions for future research and practical recommendations for strengthening youth's positive sense of place and self.
LE CAPACIT� SOCIO COGNITIVE NEL CANE DOMESTICO (CANIS FAMILIARIS): DIFFERENZE TRA RAZZE ED UN CONFRONTO CON IL LUPO(CANIS LUPUS)
Creators: name: PASSALACQUA, CHIARA ALESSANDRA
Publisher: name: Universit� degli Studi di Milano
Year: 2011

description: In the past ten years there has been a considerable increase in the number of studies on dogs? cognitive and communicative abilities. Recent evidence indicates that both genetic factors and life experiences are important in shaping dogs? socio-cognitive abilities and behaviour in a test situation. An interesting approach to the investigation of the origin of such abilities is the comparison between different dogs? breeds and with the dogs? wild ancestor: the wolf. In the present work we used two different test paradigm to investigate genetic (breed-group) and ontogenetic (age) factors influencing the use of human-directed gazing behaviour and the influence of humans on dogs? performance in a food choice task using either different of equal quantities of food. Following a genetic classification based on recent genome analyses, dogs were allocated to three breed groupings based on their vicinity to the wolf and to each other (primitive, hunting/herding and molossoid group) and were tested at different ages. Furthermore one of the two test, the ?unsolvable task? paradigm similar to that used by Mikl�si and colleagues (2003), was used to compare dogs and wolves hand raised from humans and socialized with them, to investigate the influence of genetic aspects in the use of human-directed gazing behaviour. In the ?unsolvable task? test Breed group differences did emerge strongly in adult dogs and, although less pronounced, also in 4.5-month old subjects, with dogs in the Hunting/Herding group showing significantly more human-directed gazing behaviour than dogs in the other two breed groups, whereas at two months no breed group differences emerged. Also in the social influence test we found the same pattern in adult dogs where Hunting/Herding dogs showed to follow the human choice more than the Molossoid dogs, as opposite to 4-months old dog that neither could discriminate between the two different quantity of food nor followed the humans? choice. Comparisons between dogs and wolves showed the former gazing and interacting with the person for more time and before the latter and this behaviour was already present at two months old. Taken together these results suggest an important effect of the domestication process in shaping the dog?s human-directed communicative abilities (dog-wolves differences), and contemporarily hint that the later selection for specific working attitudes in breed groups also had a significant impact on their emergence (breed-group differences).
Chiral Majorana edge states in HgTe quantum wells
Creators: name: Weithofer, Luzie
name: Recher, Patrik
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: HgTe-based quantum wells (QWs) recently attracted a lot of attention for the realization of a two-dimensional topological insulator with protected helical edge states. Another class of topological systems are topological superconductors (TSCs) with Majorana edge states. In this paper, we show how proximity induced s-wave superconductivity in the bulk of HgTe-QWs and in the presence of a Zeeman field can exhibit a TSC with chiral Majorana edge states. We calculate the topological invariants and the corresponding Majorana edge states explicitly within a four-band model accounting for inversion symmetry breaking terms due to Rashba spin-orbit coupling and bulk inversion asymmetry present in these QWs.
description: 18 pages, 8 figures, submitted to New Journal of Physics, "Focus on Majorana Fermions in Condensed Matter"
Early movements and postural characteristics in infants later diagnosed with autism spectrum disorder: a scoping review protocol
Creators: name: Hussain, Syeda
name: Seesahai, Judy
name: Banihani, Rudaina
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Medical Specialties
subject: Pediatrics
subject: Autism
subject: Autism spectrum disorder
subject: Developmental pediatrics
subject: General movements assesment
subject: Hadders-algra
subject: Prechtl

description: Background: Autism spectrum disorder is a neurodevelopmental disorder with characteristic communication and behavioral patterns. Autism spectrum disorder can be diagnosed reliably at 18-24 months. Despite the use of traditional screening tools, the diagnosis of autism spectrum disorder and predicting neurodevelopmental outcomes is challenging in high-risk populations. Early identification of motor or social characteristics in infants later diagnosed with autism spectrum disorder may lend itself to referral and implementation of early intervention programs.
title: Государственная социальная политика
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Учебное пособие посвящено концептуальным и практическим вопросам современной государственной социальной политики. В нем рассматриваются теоретические основы формирования и реализации социальной политики государства в историческом аспекте, основные её модели, особенности социальной политики в переходной экономике. Специальное внимание уделяется таким вопросам, как социальные последствия экономических решений; социальная защита населения; государственная политика на рынке труда; финансирование социальной политики и др. Учебное пособие предназначено для бакалавров, магистров, преподавателей социально-экономических, гуманитарных, политико-правовых дисциплин, а также для всех интересующихся социальной политикой государства и социальной историей.
EFFECT OF FASTING MIMICKING CONDITIONS ON HORMONE THERAPY EFFICACY AND RESISTANCE ACQUISITION IN BREAST CANCER
Creators: name: SPAGNOLO, VANESSA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: The most common cancer diagnosed among women worldwide is breast cancer (BC) with 60-80% belonging to the ER+BC subtype. Development of resistance is the major driver of ER+BC-related death. Well-tolerated treatments that allow concomitant targeting of the heterogeneous cancer cells are needed in order to abolish resistance. Fasting and fasting mimicking diets (FMD?s), acting in a broad way, have shown great potential to protect the healthy cells of the body during chemotherapeutic treatment, while augmenting treatment efficacy, mainly through lowered levels of blood glucose and circulating Insulin-like growth factor-I (IGF-I) availability. In ER+BC the interconnection of the ER signalling and the IGF1R signalling builds up a strong network difficult to target with specifically acting drugs. This work provides evidence that cycles of a vast acting FMD have the potential to postpone development of resistance to specific acting endocrine therapy (ET) and circumvent development of resistance to the combined treatment of ET and non ER+BC-specific drugs in vivo. FMD?s capacity to abolish resistance exists if applied at the onset and but also at later stages when insensitivity to these drugs has been acquired. Concomitant and early targeting exhibits a killing effect in vitro and in vivo, potentially on resistance driving subpopulations.
title: Гражданско-правовой анализ договоров по оказанию возмездных услуг частными охранными предприятиями и подразделениями вневедомственной охраны
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: В монографии рассматривается современное состояние и перспективы развития договора возмездного оказания охранных услуг. Отдельное внимание уделено вопросам анализа договоров на оказание услуг частной охранной деятельности и возмездного оказания услуг подразделениями вневедомственной охраны, особенностям заключения, изменения и расторжения этих договоров, а также изучению договоров возмездного оказания услуг по охране с помощью технических средств (централизованной охране) объекта с личным имуществом граждан и юридических лиц. Книга адресована для научных сотрудников, преподавателей, аспирантов, студентов юридических вузов и факультетов, а также для широкого круга читателей.
AMNIOTIC MEMBRANE TRANSPLANTATION FOR OCULAR SURFACE RECONSTRUCTION IN VETERINARY MEDICINE
Creators: name: BARACHETTI, LAURA
Publisher: name: Universit� degli Studi di Milano
Year: 2010

description: The fetal membrane is composed by the chorion, allantois and amnion. The AM is the inner layer. It consists of a single layer of ectodermally derived cuboidal to columnar cells, which form the epithelium, a basement membrane that connects with the chorion by a layer of mesenchyme which contains large amounts of collagen (stroma). Amniotic basement membrane and stroma contain cytokines, proteoglycans, collagen type I, III, IV, V and VII, laminin and fibronectin. Different interesting properties of the AM have been described. Amniotic basement membrane, by serving as a ?transplanted basement membrane?, acts as a new healthy substrate that facilitates migration of epithelial cells, reinforces adhesion of basal epithelial cells, promotes epithelial differentiation, and prevents epithelial apoptosis. Additionally AM produces various growth factors, inhibits protease activity, has anti-inflammatory, anti-angiogenic and antifibrotic effects. The non-immunogenicity of the AM was believed to be another important property. AM transplantation (AMT) has been widely described in human ophthalmology for the reconstruction of corneal and/or conjunctival surface in different diseases, such as: ocular surface neoplasia, pterygium, chemical and thermal burns, cicatrizing conjunctivitis, symblepharon release, bleb leakage, filtering surgery, persistent epithelial defects, non healing stromal ulcers, deep stromal ulcers and descemetoceles, neurotrophic keratopathy, limbal stem cells deficiency, bullous keratopathy, infectious keratitis, Stevens Johnson syndrome, melting ulcers, scleral melt and band keratopathy. In veterinary ophthalmology AMT has been described for the treatment of ocular surface neoplasia, bullous keratopaty, melting ulcers, symblepharon, immun-mediated keratitis and in conjunction with penetrating keratoplasty. The objective of our study was to evaluate the effects of amniotic membrane transplantation for reconstruction of the ocular surface in different diseases in dogs, cats and horses. We evaluated the cosmesis and visual function. In our case series we performed AMT with the inlay technique in 3 dogs (3 eyes), 6 cats (7 eyes) and 11 horses (11 eyes). The diseases treated were: 7 feline corneal sequestra, 4 corneal melting (1 dog and 3 horses), 2 dermoids (2 dogs), 4 keratomycosis (4 horses), 2 corneo-conjunctival squamous cell carcinoma (2 horses), 1 immunomediate keratitis (1 horse) and 1 corneal edema (1 horse). In our results the objective was obtained: we had successful outcome in 17 of the 21 eyes treated; no ocular pain was detected in the immediately postoperative period, the AM epithelialized quickly and, after the fibrovascular invasion of the AM, all the corneas obtained a good transparency and no recurrence was detected in our follow-up periods.
Development of sensitive long-wave infrared detector arrays for passively cooled space missions
Creators: name: McMurtry, Craig
name: Lee, Donald
name: Beletic, James
name: Chen, Chi-Yi A.
name: Demers, Richard T.
name: Dorn, Meghan
name: Edwall, Dennis
name: Fazar, Candice Bacon
name: Forrest, William J.
name: Liu, Fengchuan
name: Mainzer, Amanda K.
name: Pipher, Judith L.
name: Yulius, Aristo
Publisher: name: arXiv
Year: 2013
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The near-earth object camera (NEOCam) is a proposed infrared space mission designed to discover and characterize most of the potentially hazardous asteroids larger than 140 m in diameter that orbit near the Earth. NASA has funded technology development for NEOCam, including the development of long wavelength infrared detector arrays that will have excellent zodiacal background emission-limited performance at passively cooled focal plane temperatures. Teledyne Imaging Sensors has developed and delivered for test at the University of Rochester the first set of approximately 10 micron cutoff, 1024 x 1024 pixel HgCdTe detector arrays. Measurements of these arrays show the development to be extremely promising: noise, dark current, quantum efficiency, and well depth goals have been met by this technology at focal plane temperatures of 35 to 40 K, readily attainable with passive cooling. The next set of arrays to be developed will address changes suggested by the first set of deliverables.
description: 10 pages, 11 Figures
title: Исследование систем управления
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский институт управления и экономики, Ай Пи Эр Медиа
Year: 2019

description: Данное учебное пособие подготовлено в соответствии с программой одноименной дисциплины, изучение которой предусмотрено Государственным образовательным стандартом специальности «Менеджмент организации». Материал рассматривается в теоретико-методологическом, методическом и практическом аспектах. Пособие содержит вопросы для самоконтроля, планы семинарских занятий, методические рекомендации для проведения практических занятий, глоссарий, тестовые задания и задания для самостоятельной работы, а также большой объем приложений, которые должны оказать помощь студентам при изучении дисциплины. Пособие предназначено для студентов, аспирантов и преподавателей высших учебных заведений, слушателей школ бизнеса и менеджмента, руководителей, менеджеров, предпринимателей.
SOPRAVVENIENZA DI NORMA IMPERATIVA E CONTRATTO
Creators: name: CAJANI, LETIZIA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: Il presente lavoro prende in esame il tema delle sopravvenienze contrattuali e, significativamente, l?incidenza sul contratto della norma imperativa introdotta successivamente alla sua stipulazione. Una tale indagine non ha potuto non prendere avvio dall?analisi dei principi e delle norme che regolano l?efficacia nel tempo della legge civile, soprattutto al fine di verificare se l?applicazione immediata della norma sopravvenuta ai contratti ancora produttivi di effetti, costituisca una violazione del principio di irretroattivit� della legge di cui all?art. 11 delle disposizioni sulla legge in generale. Una volta escluso tale contrasto � stato necessario individuare il rimedio applicabile. Nonostante le principali tesi proposte in dottrina e giurisprudenza si siano concentrate sui rimedi invalidatori del negozio giuridico, in particolare sull?alternativa tra inefficacia e nullit� sopravvenuta del contratto, si � voluta sottolineare l?importanza dei rimedi risolutori che appaiono i pi� adatti per risolvere il problema oggetto del presente studio. Invero l?adozione di una nuova norma non derogabile destinata ad incidere sul contratto gi� perfetto con questa confliggente, si presta ad integrare un?ipotesi di impossibilit� sopravvenuta dell?oggetto, con conseguente applicabilit� della risoluzione di cui agli articoli 1463 e seguenti del codice civile, ancorch� con alcuni correttivi suggeriti dalla necessit� di tutelare efficacemente l?interesse pubblico sotteso alla disposizione introdotta. Infine si � voluto affrontare il problema speculare, consistente nel determinare l?incidenza sul negozio giuridico dell?abrogazione di una norma imperativa, valutando l?ammissibilit� di una validit� sopravvenuta.
PEDAGOGICAL POSSIBILITIES OF DEVELOPING DIVERGENT THINKING IN STUDENTS OF HIGHER MEDICAL INSTITUTIONS
Creators: name: Bekchanova, Solikha
Publisher: name: Zenodo
Year: 2023

description: This article talks about the methods used in medical higher education institutions to teach students divergent thinking and to direct them to the profession in order to strengthen their further activities. In the new Uzbekistan, the features of raising young people to be educated and thinking at a high level and improving their psychology have been revealed.