cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Design, synthesis, and in vitro gene transfer efficacy of novel ionizable cholesterol derivatives
Creators: name: Wang, Yajing
name: Jiang, Jiahui
name: Ding, Ziwei
name: Zhang, Tao
name: Shi, Yingying
name: Huang, Xianfeng
name: Shen, Xiaozhong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: The medicinal properties of genetic drugs are highly dependent on the design of delivery systems. Ionizable cationic lipids are considered core materials in delivery systems. However, there has not yet been a widespread consensus on the relationship between the wide diversity of lipid structure design and gene delivery efficiency. The aims of the research work were to synthesize ionizable cholesterol derivatives (iChol-lipids) and to evaluate their potential applications as gene delivery vector. A series of iChol-lipids with different head groups were synthesized with carbamate bond spacer. The chemical structures were characterized by 1H NMR, MS, melting range, and pKa. The interactions between iChol-lipids and MALAT1-siRNA were studied by molecular dynamics simulations and compared with market available DC-Chol, which revealed that hydrogen bonds, salt-bridge, and electrostatic interaction were probably involved. The self-assemble behaviors of these lipids were intensively investigated and evaluated by dynamic laser scattering in the presence of different helper lipids and PEGylated lipids. Their plasmid binding ability, transfection efficiency, hemolytic toxicity, and cytotoxicity were fully studied. IZ-Chol-LNPs was proved to be highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect was verified by pH-sensitive fluorescence probe BCFL.
EFFECTS OF METFORMIN ON MITOCHONDRIA, METABOLISM, AND FUNCTION OF CD4+ T CELL SUBSETS IN OBESITY
Creators: name: Rajeev, Devika
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Obesity, characterized by inflammation, leads to poor response to select viral infections. Our lab has identified that T cells, critical players of infection response, have increased glucose oxidation, which can be normalized with metformin treatment. Metformin mechanisms are presumably mediated through mitochondrial electron transport inhibition. To investigate mitochondrial mechanisms of metformin-mediated changes in T cell metabolism and function, CD4+ T cells were isolated from diet-induced obese mice and differentiated in vitro toward T effector cells (Teff: Th1 or Th17) or regulatory T cells (Treg) in the presence or absence of metformin. Metformin alters T cell mitochondrial metabolism and function differentially in anti-inflammatory Treg cells versus proinflammatory Teff cells, significantly decreasing mitochondrial membrane potential and downstream complex I activity in Treg cells and altering phosphorylation of AMP kinase in Th17 cells. Further elucidating mechanisms by which metformin alters T cell responses may provide novel therapeutic approaches to obesity-associated dysfunction.
A catalogue of nuclear stellar velocity dispersions of nearby galaxies from H$α$ STIS spectra to constrain supermassive black hole masses
Creators: name: Pagotto, I.
name: Corsini, E. M.
name: Sarzi, M.
name: Pagani, B.
name: Bontà, E. Dalla
name: Morelli, L.
name: Pizzella, A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present new measurements for the nuclear stellar velocity dispersion $σ_{\ast}$ within sub-arcsecond apertures for 28 nearby galaxies. Our data consist of Space Telescope Imaging Spectrograph (STIS) long-slit spectra obtained with the G750M grating centred on the H$α$ spectral range. We fit the spectra using a library of single stellar population models and Gaussian emission lines, while constraining in most cases the stellar-population content from an initial fit to G430L STIS spectra. We illustrate how these $σ_{\ast}$ measurements can be useful for constraining the mass $M_{\bullet}$ of supermassive black holes (SBHs) by concentrating on the cases of the lenticular galaxies NGC4435 and NGC4459. These are characterized by similar ground-based half-light radii stellar velocity dispersion $σ_{\rm e}$ values but remarkably different $M_{\bullet}$ as obtained from modelling their central ionised-gas kinematics, where NGC4435 appears to host a significantly undermassive SBH compared to what is expected from the $M_{\bullet}-σ_{\rm e}$ relation. For both galaxies, we build Jeans axisymmetric dynamical models to match the ground-based stellar kinematics obtained with SAURON integral-field spectrograph, including a SBH with $M_{\bullet}$ value as predicted by the $M_{\bullet}-σ_{\rm e}$ relation and using high-resolution HST images taken with the Advanced Camera for Surveys to construct the stellar-mass model. By mimicking the HST observing conditions we use such reference models to make a prediction for the nuclear $σ_{\ast}$ value. Whereas this was found to agree with our nuclear $σ_{\ast}$ measurement for NGC4459, for NGC4435 the observed $σ_{\ast}$ is remarkably smaller than the predicted one, which further suggests that this galaxy could host an undermassive SBH.
description: 14 pages, 8 figures, MNRAS accepted
Supplement B
Creators: name: Kappler, Lisa
name: Hoene, Miriam
name: Chunxiu Hu
name: Toerne, Christine Von
name: Li, Jia
name: Bleher, Daniel
name: Hoffmann, Christoph
name: Böhm, Anja
name: Laxmikanth Kollipara
name: Zischka, Hans
name: Königsrainer, Alfred
name: Hans-Ulrich Häring
name: Peter, Andreas
name: Guowang Xu
name: Sickmann, Albert
name: Hauck, Stefanie M.
name: Weigert, Cora
name: Lehmann, Rainer
Publisher: name: figshare
Year: 2019
Subjects: subject: 60101 Analytical Biochemistry
subject: FOS: Biological sciences
subject: Cell Biology
subject: 60104 Cell Metabolism
subject: 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

description: Detailed proteomics data table covering all proteins detected in skeletal muscle and liver mitochondria by LC-MS/MS
Additional file 2 of Identification and validation of plant height, spike length and spike compactness loci in common wheat (Triticum aestivum L.)
Creators: name: Liu, Hong
name: Shi, Zhipeng
name: Ma, Feifei
name: Xu, Yunfeng
name: Han, Guohao
name: Zhang, Jinpeng
name: Liu, Dongcheng
name: An, Diaoguo
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Supplementary file 2.
Inhomogeneous cosmologies with Q-matter and varying $Λ$
Creators: name: Chimento, Luis P.
name: Jakubi, Alejandro S.
name: Pavon, Diego
Publisher: name: arXiv
Year: 1999
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Starting from the inhomogeneous shear--free Nariai metric we show, by solving the Einstein--Klein--Gordon field equations, how a self--interacting scalar field plus a material fluid, a variable cosmological term and a heat flux can drive the universe to its currently observed state of homogeneous accelerated expansion. A quintessence scenario where power-law inflation takes place for a string-motivated potential in the late--time dominated field regime is proposed.
description: 11 pages, Revtex. To be published in Physical Review D
Presentism May Be Tenable, but Only at the Expense of Its Intuitiveness
Creators: name: Benzant, Felix A
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Presentism—the thesis that only present things exists—is regarded by many philosopher as the intuitive or commonsensical position in the literature on time. In this paper, I argue that the very features that give presentism its purportedly intuitive or commonsensical appeal are features that, under scrutiny, lead to untoward consequences for the view: they render it either false or counterintuitive. I propose that the only plausible alternative for the presentist is to accept a form of presentism stripped of its intuitive or commonsensical features. But, as I shall also argue, this latter move undermines the main motivation for accepting it in the first place.
Additional file 11 of Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications
Creators: name: Muranen, Taru A
name: Greco, Dario
name: Fagerholm, Rainer
name: Kilpivaara, Outi
name: Kämpjärvi, Kati
name: Aittomäki, Kristiina
name: Blomqvist, Carl
name: Heikkilä, Päivi
name: Borg, Åke
name: Nevanlinna, Heli
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 1
Additional file 12 of Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications
Creators: name: Muranen, Taru A
name: Greco, Dario
name: Fagerholm, Rainer
name: Kilpivaara, Outi
name: Kämpjärvi, Kati
name: Aittomäki, Kristiina
name: Blomqvist, Carl
name: Heikkilä, Päivi
name: Borg, Åke
name: Nevanlinna, Heli
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Authors’ original file for figure 2
Sabalia picarina Walker 1865
Creators: name: Mbata, Keith J.
name: Prins, Jurate De
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Brahmaeidae
Sabalia
Sabalia picarina

description: Sabalia picarina Walker, 1865b
COMMON NAME(S): Brahmin Moth.
SYNONYM(S): None.
IUCN STATUS: Not Evaluated (NE).
DISTRIBUTION: Burundi, Democratic Republic of Congo, Kenya, Mozambique, South Africa, Tanzania, Zambia, Zimbabwe.
LOCALITY IN ZAMBIA: Type locality is in [Zambia], in the Zambesi Region, without specification of part of the Zambezi River region which is found in the Northwestern, Western, Southern or Lusaka Provinces of the country Zambia.
LARVAL HOSTPLANT(S): Unknown.
SOURCES: African Moths 2019; De Prins & De Prins 2022; Naumann 2008.
description: Published as part of Mbata, Keith J. & Prins, Jurate De, 2023, Annotated checklist of moths of Zambia (Insecta: Lepidoptera), pp. 1-503 in Zootaxa 5354 (1) on page 140, DOI: 10.11646/zootaxa.5354.1.1, http://zenodo.org/record/10130434
Unveiling Linguistic Authenticity: Analysis of AAE in Performative Poetry
Creators: name: Amundsen, Cassidy Grace
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: This research delves into the dynamics of stigma and authenticity in nonstandard dialects, particularly African American English (AAE), within performance poetry. Central to the study is how poets' deliberate integration of AAE features provides a linguistically diverse setting, cultivating community solidarity and reflecting authenticity. Drawing on various sociolinguistic theories including Giles’ (1991) Accommodation Theory, Brown and Levinson's (1978) Politeness Theory, Bell's (1984) Audience Design Theory, Schilling-Estes’ (2002) Speaker Design Theory, Kiesling & Schilling-Estes’ (1998) Footing and Framing Approach, and Labov's (2001) variationist sociolinguistic studies, the research explores how the deliberate incorporation of stigmatized dialectical features promotes linguistic authenticity and cultural solidarity within performative poetry events.Non-standard dialects like AAE often face stigma in mainstream contexts, extending to the speakers themselves, suggesting that identifiable features of non-standard language can symbolize group membership, solidarity, and authenticity. The research suggests an inverse relationship between mainstream stigma and authenticity in poetry contexts, proposing that artists utilize dialect stigma to foster solidarity, resulting in the heightened use of stigmatized features in performances compared to conversational settings. The features of AAE analyzed are habitual be, absence of copula, present tense third person -s absence, possessive -s absence, remote time stressed been, consonant cluster reduction, transposed sk and sp, g-dropping, r-lessness and l-lessness, monophthongization, and mutations for dental fricatives involving /t/, /d/, /f/ or /v/ replacing dental fricatives (Green 2002; Thomas 2010).This investigation acknowledges the negative stigmas associated with AAE and explores how speakers challenge established linguistic norms by employing linguistic diversity in artistic expression. Employing a mixed-methods approach, including a comparative analysis of dialectal features employed in live performances versus interview audio, along with a sentiment analysis using VADER to exploit known racial bias in automated Natural Language Processing (NLP), the study reveals patterns and motivations underlying poets' linguistic selections, aimed at conveying authenticity and fostering solidarity among group members. By examining how poets strategically implement dialectal features, the research contributes insights into the connection between cultural appreciation and stigmatized language in performance settings.
Beta Function Quintessence Cosmological Parameters and Fundamental Constants II: Exponential and Logarithmic Dark Energy Potentials
Creators: name: Thompson, Rodger I.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: This paper uses the beta function formalism to extend the analysis of quintessence cosmological parameters to the logarithmic and exponential dark energy potentials. The previous paper (Thompson 2018) demonstrated the formalism using power and inverse power potentials. The essentially identical evolution of the Hubble parameter for all of the quintessence cases and LambdaCDM is attributed to the flatness of the quintessence dark energy potentials in the dark energy dominated era. The Hubble parameter is therefore incapable of discriminating between static and dynamic dark energy. Unlike the other three potentials considered in the two papers the logarithmic dark energy potential requires a numerical integration in the formula for the superpotential rather than being an analytic function. The dark energy equation of state and the fundamental constants continue to be good discriminators between static and dynamical dark energy. A new analysis of quintessence with all four of the potentials relative the swampland conjectures indicates that the conjecture on the change in the scalar field is satisfied but that the conjecture on the change of the potential is not.
description: Accepted for publication in the MNRAS,
Additional file 5 of Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications
Creators: name: Muranen, Taru A
name: Greco, Dario
name: Fagerholm, Rainer
name: Kilpivaara, Outi
name: Kämpjärvi, Kati
name: Aittomäki, Kristiina
name: Blomqvist, Carl
name: Heikkilä, Päivi
name: Borg, Åke
name: Nevanlinna, Heli
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5: Sample-selection criteria and survival-analysis end points in Uppsala, Stockholm, and Rotterdam cohorts. (PDF 4 KB)
Final Report OSS Saint-Louis
Creators: name: Space for Climate Observatory
Publisher: name: GEO Knowledge Hub
Year: 2024
Subjects: Coastlines
Coastal erosion
Flooding
Climate change
Sea level rise
Storm surges
Rainfall
Saltwater intrusion
Pollution
Mangrove destruction
Ocean
Copernicus
Sentinel-1
Sentinel-2
Sentinel-3

description: This is the Final Report of OSS Saint Louis project for the case of Senegal. It is available in French.
A soluble model of evolution and extinction dynamics in a rugged fitness landscape
Creators: name: Sibani, Paolo
Publisher: name: arXiv
Year: 1997
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We consider a continuum version of a previously introduced and numerically studied model of macroevolution (PRL 75, 2055, (1995)) in which agents evolve by an optimization process in a rugged fitness landscape and die due to their competitive interactions. We first formulate dynamical equations for the fitness distribution and the survival probability. Secondly we analytically derive the $t^{-2}$ law which characterizes the life time distribution of biological genera. Thirdly we discuss other dynamical properties of the model such as the rate of extinction and conclude with a brief discussion.
description: 6 pages LaTeX source with 2 figures. Submitted to PRL (Jan. 97)
Additional file 3 of Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications
Creators: name: Muranen, Taru A
name: Greco, Dario
name: Fagerholm, Rainer
name: Kilpivaara, Outi
name: Kämpjärvi, Kati
name: Aittomäki, Kristiina
name: Blomqvist, Carl
name: Heikkilä, Päivi
name: Borg, Åke
name: Nevanlinna, Heli
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Unsupervised clustering of array-comparative genomic hybridization (aCGH) and gene-expression (GEX) data. Left, aCGH samples do not cluster according to any of the covariates. Instead, the clustering is based on informative genomic regions and tumors' overall copy-number profiles. Right, unsupervised hierarchical clustering of gene-expression data suggests that estrogen receptor (ER) status and family history of breast cancer have an impact on the tumor's gene-expression profile. The effect of the other variables is likely to be smaller. Replicates that were used as a quality control cluster together as expected. Positions of CHEK2 (checkpoint kinase 2), 1100delC-mutation carrier and control (contr) tumors are indicated by the uppermost color block. NQO1- and NQO1+ stand for samples with germline rs1800566 genotypes: homozygotes of the more common allele (CC) and heterozygotes or homozygotes of the rarer allele (CT or TT), respectively. Frequency of copy-number changes along the genome is depicted with a color scale from blue to red. Blue, few; red, frequent copy-number aberrations. (PDF 115 KB)
TА'LIMDА АXBOROT TEXNOLOGIYАLАRIDАN FOYDАLАNISHNING NАZАRIY АSOSLАRI
Creators: name: Аbdullаyevа, Mа'murа
Publisher: name: Zenodo
Year: 2024

description: Mаzkur mаqolаdа bugungi kundа tа’lim jаrаyonidа аxborot texnologiyаlаridаn foydаlаnishning ilmiy-nаzаriy аsoslаri vа аhаmiyаti hаqidа fikr-mulohаzаlаr yuritilаdi.
MoDPA: Investigating diseases through Modification-Dependent Protein Associations
Creators: name: Massignani, Enrico
name: Martens, Lennart
Publisher: name: F1000 Research Limited
Year: 2024

description: MoDPA is a computational approach that aims to identify functional associations between post-translational modifications (PTMs).

Co-expression analysis is a widely utilized method for exploring the function and regulation of genes. Various techniques exist for assessing the relationship between two proteins, the simplest being based on co-occurrence. MoDPA employs a similar approach to identify clusters of PTMs that consistently co-occur across proteomics experiments.
Additional file 1: of Effectiveness of Yi-Zhi-An-Shen granules on cognition and sleep quality in older adults with amnestic mild cognitive impairment: protocol for a randomized, double-blind, placebo-controlled trial
Creators: name: Yue, Shengnan
name: He, Ting
name: Li, Baiyang
name: Qu, Yanqin
name: Peng, Hongmei
name: Chen, Jinxin
name: Lei, Ming
name: Chen, Chongli
name: Wu, Wenbin
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mental Health

description: SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 138 kb)
Isospectral manifolds with different local geometries
Creators: name: Schueth, Dorothee
Publisher: name: arXiv
Year: 2001
Subjects: subject: Differential Geometry (math.DG)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: 58J53

description: We construct several new classes of isospectral manifolds with different local geometries. After reviewing a theorem by Carolyn Gordon on isospectral torus bundles and presenting certain useful specialized versions (Chapter 1) we apply these tools to construct the first examples of isospectral four-dimensional manifolds which are not locally isometric (Chapter 2). Moreover, we construct the first examples of isospectral left invariant metrics on compact Lie groups (Chapter 3). Thereby we also obtain the first continuous isospectral families of globally homogeneous manifolds and the first examples of isospectral manifolds which are simply connected and irreducible. Finally, we construct the first pairs of isospectral manifolds which are conformally equivalent and not locally isometric (Chapter 4).
description: 59 pages, AMS-TeX. Habilitation thesis (2000), to appear in: J. Reine Angew. Math
Scene Synchronization for Real-Time Interaction in Distributed Mixed Reality and Virtual Reality Environments
Creators: name: Hamza-Lup, Felix G.
name: Rolland, Jannick P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: Advances in computer networks and rendering systems facilitate the creation of distributed collaborative environments in which the distribution of information at remote locations allows efficient communication. One of the challenges in networked virtual environments is maintaining a consistent view of the shared state in the presence of inevitable network latency and jitter. A consistent view in a shared scene may significantly increase the sense of presence among participants and facilitate their interactivity. The dynamic shared state is directly affected by the frequency of actions applied on the objects in the scene. Mixed Reality (MR) and Virtual Reality (VR) environments contain several types of action producers including human users, a wide range of electronic motion sensors, and haptic devices. In this paper, the authors propose a novel criterion for categorization of distributed MR/VR systems and present an adaptive synchronization algorithm for distributed MR/VR collaborative environments. In spite of significant network latency, results show that for low levels of update frequencies the dynamic shared state can be maintained consistent at multiple remotely located sites.
Between Madras and New York City: The Materiality and Making of Hanuman Books, 1986 – 1993
Creators: name: Beattie, Callie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Founded by writer, editor, and curator Raymond Foye and artist Francesco Clemente, Hanuman Books was a small press that published fifty pocket-sized books between 1986 and 1993. The press embodies both modernity and antiquity as each Hanuman book pairs original written works with a physical form that reflects day-to-day Indian popular culture, traditional artisan techniques, and the subversive spirit of the New York Downtown scene. Collaboration and cultural exchange were at the heart of Hanuman Books as they pulled together two different cultures and intended to unify artists and writers. Despite Hanuman Books’ significant creative contributions and underground cult status, the press has been largely overlooked in academic scholarship. This thesis employs archival evidence and material analysis to provide a much-needed historical overview of the visual aesthetics, distinct materiality, and intercontinental production processes of the press to demonstrate the importance of Hanuman Books as an influential creative network and artists’ book press worthy of further scholarship.
Capturing Heterogeneous Patient Needs in Hospitals: A Machine Learning Approach to Predict Staffing Needs: Supplementary Material
Creators: name: Anonymous, Anonymous
Publisher: name: Zenodo
Year: 2025

description: This supplementary material accompanies the paper 'Capturing Heterogeneous Patient Needs in Hospitals: A Machine Learning Approach to Predict Staffing Needs' (currently under review), offering additional details on the training procedures of the machine learning models used in the study. It includes expanded descriptions of the datasets utilized, the search spaces for hyperparameters, and configurations of the machine learning models, and additional results. This additional document is provided to improve transparency, offer more detailed insights into the study’s methodology, and support further exploration by interested researchers.
Gauge Fixing in Higher Derivative Gravity
Creators: name: Bartoli, A.
name: Julve, J.
name: Sanchez, E. J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Linearized four-derivative gravity with a general gauge fixing term is considered. By a Legendre transform and a suitable diagonalization procedure it is cast into a second-order equivalent form where the nature of the physical degrees of freedom, the gauge ghosts, the Weyl ghosts, and the intriguing "third ghosts", characteristic to higher-derivative theories, is made explicit. The symmetries of the theory and the structure of the compensating Faddeev-Popov ghost sector exhibit non-trivial peculiarities.
description: 21 pages, LaTeX
title: Zwanzigster Jahresbericht der Gottfried Keller-Gesellschaft 1951
title: Jahresbericht / Gottfried Keller-Gesellschaft (1932-1993)
titleType: AlternativeTitle
Creators: name: Weber, Werner
Publisher: name: Verlag der Gottfried Keller-Gesellschaft
Year: 1952
Subjects: subject: 800 Literatur und Rhetorik
subject: Keller, Gottfried
subject: Gottfried Keller-Gesellschaft
subject: Bericht
subject: Deutsche Literatur
subject: Freundschaft
subject: Rede
subject: Rathaus Zürich

description: Rede "Freundschaften Gottfried Kellers, Versuch über die Einsamkeit eines Genies" von Werner Weber, gehalten am Jahresbott der Gottfried Keller-Gesellschaft am 28. Oktober 1951 im Rathaus Zürich.
Capturing Heterogeneous Patient Needs in Hospitals: A Machine Learning Approach to Predict Staffing Needs: Supplementary Material
Creators: name: Anonymous, Anonymous
Publisher: name: Zenodo
Year: 2025

description: This supplementary material accompanies the paper 'Capturing Heterogeneous Patient Needs in Hospitals: A Machine Learning Approach to Predict Staffing Needs' (currently under review), offering additional details on the training procedures of the machine learning models used in the study. It includes expanded descriptions of the datasets utilized, the search spaces for hyperparameters, and configurations of the machine learning models. This additional document is provided to improve transparency, offer more detailed insights into the study’s methodology, and support further exploration by interested researchers.
Using ELIXIR supported infrastructure to access Human Genomic data at scale
Creators: name: Chegkazi, Magda S.
name: Kerry, Giselle
name: Scollen, Serena
Publisher: name: F1000 Research Limited
Year: 2024

description: Enabling secure access to genomic and corresponding health data across Europe has become a realisation due to the progress made by ELIXIR and the 1+MG initiative. ELIXIR has been building infrastructure and capacity for genomic data for a decade through active Communities and internally or externally funded projects. Since 2020, ELIXIR has acted as a neutral broker for the 1+MG Member State countries, coordinating implementation projects for both the design and testing and the scale-up and sustainability phases. Outcomes have included the 1+MG framework, which houses the guidelines and recommendations for the technical framework and implementation. The European Genomic Data Infrastructure (GDI) project is now being deployed to facilitate federated access and analysis of genomic, phenotypic and clinical data in secure environments, advancing personalised medicine and medical research, and fostering innovation in health technologies with the use cases, e.g., Cancer and Infectious Disease in place to maximise data harmonisation and standardisation.

The Human Data and Translational Research (HDTR) priority area embedded in the Science tier of the ELIXIR 2024-2028 Programme focuses on: 

 Accessible genomic and affiliated data deposited into ELIXIR-supported federated human genomic data infrastructure
 Federated analysis of data demonstrated for use, e.g., in rare diseases, cancer, pharmacogenomics.
 Partnerships linking human genomics to heterogeneous data using ELIXIR-supported infrastructures and services ensuring interoperability and metadata alignment. 

These activities support both the progress made in Europe and ELIXIR’s vision to facilitate discoverability, access, sharing and analysis of genomics data linked to other data types at scale.
Entropy from Conformal Field Theory at Killing Horizons
Creators: name: Carlip, S.
Publisher: name: arXiv
Year: 1999
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: On a manifold with boundary, the constraint algebra of general relativity may acquire a central extension, which can be computed using covariant phase space techniques. When the boundary is a (local) Killing horizon, a natural set of boundary conditions leads to a Virasoro subalgebra with a calculable central charge. Conformal field theory methods may then be used to determine the density of states at the boundary. I consider a number of cases---black holes, Rindler space, de Sitter space, Taub-NUT and Taub-Bolt spaces, and dilaton gravity---and show that the resulting density of states yields the expected Bekenstein-Hawking entropy. The statistical mechanics of black hole entropy may thus be fixed by symmetry arguments, independent of details of quantum gravity.
description: 26 pages, LaTeX; corrected typo and minor changes in Misner string section
Isotropy vs anisotropy in small-scale turbulence
Creators: name: Biferale, L.
name: Vergassola, M.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: The decay of large-scale anisotropies in small-scale turbulent flow is investigated. By introducing two different kinds of estimators we discuss the relation between the presence of a hierarchy for the isotropic and the anisotropic scaling exponents and the persistence of anisotropies. Direct measurements from a channel flow numerical simulation are presented.
description: 7 pages, 2 figures
The one dimensional semi-classical Bogoliubov-de Gennes Hamiltonian with PT symmetry: generalized Bohr-Sommerfeld quantization rules
Creators: name: Ifa, Abdelwaheb
name: Rouleux, Michel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present a method for computing first order asymptotics of semiclassical spectra for 1-D Bogoliubov-de Gennes (BdG) Hamiltonian from Supraconductivity, which models the electron/hole scattering through two SNS junctions. This involves: 1) reducing the system to Weber equation near the branching point at the junctions, 2) constructing local sections of the fibre bundle of microlocal solutions, 3) normalizing these solutions for the "flux norm" associated to the microlocal Wronskians, 4) finding the relative monodromy matrices in the gauge group that leaves invariant the flux norm, 5) from this we deduce Bohr-Sommerfeld (BS) quantization rules that hold precisely when the fibre bundle of microlocal solutions (depending on the energy parameter E) has trivial holonomy. Such a semi-classical treatement reveals interesting continuous symetries related to monodromy.
description: IOP Conference series GROUP32
On primordial cosmological density fluctuations in the Einstein-Cartan gravity and COBE data
Creators: name: Palle, D.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study cosmological density fluctuations within a covariant and gauge-invariant fluid-flow approach for a perfect fluid in the Einstein-Cartan gravity and derive the corresponding Raychaudhuri type of inhomogeneous coupled differential evolution equations of the second order. It appears that the quantum fluctuations of spin trigger primordial density inhomogeneities at the scale of weak interactions. These inhomogeneities are then evolved precisely to the value measured be COBE mission at the scale of decoupling.
description: 10 pages, LaTeX style
Proof-of-principle experiment for nanoparticle-assisted laser wakefield acceleration
Creators: name: Aniculaesei, Constantin
name: Pathak, Vishwa Bandhu
name: Oh, Kyung Hwan
name: Hojbota, Calin Ioan
name: Singh, Prashant Kumar
name: Lee, Bo Ram
name: Kim, Hyung Taek
name: Brunetti, Enrico
name: Yoo, Byung Ju
name: Sung, Jae Hee
name: Lee, Seong Ku
name: Nam, Chang Hee
Publisher: name: arXiv
Year: 2019
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: In the present work, we demonstrate for the first time a proof-of-principle experiment for nanoparticle-assisted laser wakefield acceleration. The nanoparticles, generated through laser ablation of aluminium, were introduced into the plasma and used to trigger the injection of electrons into the nonlinear plasma wake excited by a high power femtosecond laser. In this experiment, a significant enhancement of the electron beam energy, energy spread and divergence is obtained compared with the case when electrons are self-injected. The best quality electron bunches presented peak energy up to 338 MeV with a relative energy spread of 4.7% and vertical divergence of 5.9 mrad. This method can be further improved by adding an aerodynamic lens system, for instance, which would control the nanoparticle size, density, material and injection position thus allowing accurate control of the laser wakefield accelerator.
On the weak field approximation for CaII 8542 A
Creators: name: Centeno, Rebecca
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The weak field approximation (WFA) is a conceptually simple and computationally light method for inferring the magnetic field strength and its orientation in the Sun's atmosphere. In this work we study the validity and limitations of this tool when applied to full Stokes Ca II 8542 A profiles to extract information about the chromospheric magnetic field. We find that the range of validity of the WFA depends, amongst other things, on the component of the magnetic field that one is trying to infer. The retrieval of line-of-sight component of the chromospheric magnetic field from the core of the spectral line is reliable for field strengths up to ~1200 G, even when moderate velocity gradients are present. The horizontal component, on the other hand, is suitably derived using the wing-core boundary of the spectral line, but typically yields systematic errors of >10%. The effects of scattering polarization further compound the problem by rendering the transverse field inference problematic in quiet Sun areas, and for observing geometries within 30 degrees of the limb. Magneto-optical effects disproportionately challenge the determination of the magnetic field azimuth in the transverse plane, leading to errors of ~10 degrees. Typical noise levels of 10d-3 relative to the continuum intensity preclude the accurate retrieval of the transverse field strength and its azimuth below a threshold of a few hundred gauss. Striving for a noise level of 10d-4 significantly improves the diagnostic capability of the WFA with this spectral line, at which point the magnetic field inference becomes limited by systematic errors.
description: Published in ApJ
Quantum Kaluza-Klein Compactification
Creators: name: Sochichiu, C.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Kaluza--Klein compactification in quantum field theory is analysed from the perturbation theory viewpoint. Renormalisation group analysis for compactification size dependence of the coupling constant is proposed.
description: Latex2e, 10pp
Synchronization learning of coupled chaotic maps
Creators: name: Moyano, Luis G.
name: Abramson, Guillermo
name: Zanette, Damian H.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the dynamics of an ensemble of globally coupled chaotic logistic maps under the action of a learning algorithm aimed at driving the system from incoherent collective evolution to a state of spontaneous full synchronization. Numerical calculations reveal a sharp transition between regimes of unsuccessful and successful learning as the algorithm stiffness grows. In the regime of successful learning, an optimal value of the stiffness is found for which the learning time is minimal.
Adafroptilum coccineum Darge 2013
Creators: name: Mbata, Keith J.
name: Prins, Jurate De
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Saturniidae
Adafroptilum
Adafroptilum coccineum

description: Adafroptilum coccineum Darge, 2013a
COMMON NAME(S): Saturniid.
SYNONYM(S): None.
IUCN STATUS: Not Evaluated (NE)
DISTRIBUTION: Known only from Zambia (endemic species).
LOCALITY IN ZAMBIA: Type locality is Rufunsa Ranch in Lower Zambesi [now Zambezi] National Park [Latitude, - 15°22’0” South; Longitude, 29°18’0” East; Altitude, 3730 ft or 1136.9 m], in Lusaka Province.
LARVAL HOSTPLANT(S): Unknown.
SOURCES: Darge 2013b; De Prins & De Prins 2022.
description: Published as part of Mbata, Keith J. & Prins, Jurate De, 2023, Annotated checklist of moths of Zambia (Insecta: Lepidoptera), pp. 1-503 in Zootaxa 5354 (1) on page 141, DOI: 10.11646/zootaxa.5354.1.1, http://zenodo.org/record/10130434
On Two Moduli Problems Concerning Number of Points and Equidistribution over Prime Finite Fields
Creators: name: Glazunov, Nikolaj
Publisher: name: arXiv
Year: 2001
Subjects: subject: Number Theory (math.NT)
subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 11F10; 11K20

description: Problems of (i) precise (exact) bound for families of hyperelliptic curves over prime finite fields and (ii) equidistribution of angles of Kloosterman sums are discussed.
description: 5 pages. Extended version of Proc. from Int. Conf. on Discrete Models in Control System Theory, Krasnovidovo, (June 22-27, 1998),- Moscow: MGU
M-theory resolution of four-dimensional cosmological singularities via U-duality
Creators: name: Feinstein, A.
name: Vazquez-Mozo, M. A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider cosmological solutions of string and M-theory compactified to four dimensions by giving a general prescription to construct four-dimensional modular cosmologies with two commuting Killing vectors from vacuum solutions. By lifting these solutions to higher dimensions we analyze the existence of cosmological singularities and find that, in the case of non-closed Friedmann-Robertson-Walker universes, singularities can be removed from the higher-dimensional model when only one of the extra dimensions is time-varying. By studying the moduli space of compactifications of M-theory resulting in homogeneous cosmologies in four dimensions we show that U-duality transformations map singular cosmologies into non-singular ones.
description: 21 pages, harvmac. No figures. Minor changes. Typos corrected, a footnote added in Sec. 3 and two words added to the title. Final version to appear in Nuclear Physics B
Additional file 1 of Evolution and functional analysis of the GRAS family genes in six Rosaceae species
Creators: name: Bai, Yibo
name: Liu, Hui
name: Zhu, Kaikai
name: Cheng, Zong-Ming
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Phylogenetic tree of GRAS genes among six Rosaceae species. Red oval means species-specific duplication and red square indicate lineage-specific duplication events.
Travelling solitons in the parametrically driven nonlinear Schroedinger equation
Creators: name: Barashenkov, I. V.
name: Zemlyanaya, E. V.
name: Baer, M.
Publisher: name: arXiv
Year: 2000
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We show that the parametrically driven nonlinear Schroedinger equation has wide classes of travelling soliton solutions, some of which are stable. For small driving strengths nonpropogating and moving solitons co-exist while strongly forced solitons can only be stably when moving sufficiently fast.
description: The paper is available as the JINR preprint E17-2000-147(Dubna, Russia) and the preprint of the Max-Planck Institute for the Complex Systems mpipks/0009011, Dresden, Germany. It was submitted to Physical Review E
When Strangers Arrive: Host-Visitor Protocol in the Pre-Contact Caribbean
Creators: name: Quiñones, Sebastián Moises
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Scholars describe the pre-Contact Caribbean as interconnected but do not explicitly explain how Indigenous peoples maintained these ties. Early Indo-Hispanic encounters in the Caribbean reveal behavior patterns among Indigenous peoples that, upon closer inspection, appear more as protocols for host-visitor interactions born from conflict and increased contact rather than one-off reactions to the Spaniards’ arrival. These protocols involved the vetting of outsiders, the use of gift-giving as an avenue towards diplomacy and commerce, and the de-escalation of conflict. Indigenous Caribbean peoples possessed elaborate and recognized diplomatic protocols that emerged from and facilitated interactions across ethnic, cultural, and political boundaries and shaped Indigenous action during the colonial period.
Lyapunov exponents as a dynamical indicator of a phase transition
Creators: name: Barre, Julien
name: Dauxois, Thierry
Publisher: name: arXiv
Year: 2001
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We study analytically the behavior of the largest Lyapunov exponent $λ_1$ for a one-dimensional chain of coupled nonlinear oscillators, by combining the transfer integral method and a Riemannian geometry approach. We apply the results to a simple model, proposed for the DNA denaturation, which emphasizes a first order-like or second order phase transition depending on the ratio of two length scales: this is an excellent model to characterize $λ_1$ as a dynamical indicator close to a phase transition.
description: 8 Pages, 3 Figures
CHARACTERIZATION OF T-SITES IN FOLDED RNAS
Creators: name: Aponte, Amy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: RNAs fold into complex tertiary structures crucial for function. The functions of riboswitches, ribozymes, and ribosomal RNA all require properly folded tertiary structures. The ability to identify RNA tertiary structures de novo would likely reveal new functional motifs, but the tertiary structures of most RNAs have not been characterized due to limitations in current RNA structural characterization technologies. Recently, our lab developed a differential chemical probing method that uses two methylating agents, trimethyl oxonium and dimethyl sulfate. We found that nucleotides with high reactivity with trimethyl oxonium and relatively low reactivity with dimethyl sulfate uniquely occur in a specific type of tertiary structure interaction. We call these trimethyl oxonium-reactive sites indicative of RNA tertiary structure T-sites. We demonstrate by structural analyses that the T-site reactivity mechanism relies on the presence of an electronegative pocket created by multiple non-bridging oxygens near an unpaired adenosine constrained in space.
Edge states in a two-dimensional non-symmorphic semimetal
Creators: name: Matveeva, P. G.
name: Aristov, D. N.
name: Meidan, D.
name: Gutman, D. B.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Dirac materials have unique transport properties, partly due to the presence of surface states. A new type of Dirac materials, protected by non-symmorphic symmetries was recently proposed by Young and Kane [1]. By breaking of time reversal or inversion symmetry one can split the Dirac cones into Weyl nodes. The later are characterized by local Chern numbers, that makes them two-dimensional analogs of Weyl semimetals. We find that the formation of the Weyl nodes is accompanied by an emergence of one-dimensional surface states, similar to Fermi arcs in Weyl semimetals and edge states in two-dimensional graphene. We explore these states for a quasi-one-dimensional non-symmorphic ribbon. The type and strength of applied deformation control the location and Weyl nodes and their composition. This determines the properties of emerging edge states. The sensitivity of these edge states to the external deformations makes non-symmorphic materials potentially useful as a new type of electromechanical sensors.
description: 9 pages, 8 figures
On Bose-Einstein condensation on closed Robertson-Walker spacetimes
Creators: name: Trucks, M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this letter we summarize our analysis of Bose-Einstein condensation on closed Robertson-Walker spacetimes. In a previous work we defined an adiabatic KMS state on the Weyl-algebra of the free massive Klein-Gordon field. This state describes a free Bose gas on Robertson-Walker spacetimes. We use this state to analyze the possibility of Bose-Einstein condensation on closed Robertson-Walker spacetimes. We take into account the effects due to the finiteness of the spatial volume and show that they are not relevant in the early universe. Furthermore we show that a critical radius can be defined. The condensate disappears above the critical radius.
description: 9 pages, 1 figure, uses elsart.cls