cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
D2.3 Online Stakeholder Engagement Support Tool
Creators: name: Lopiparo, Luigi
name: Nieto, Enrique
Publisher: name: Zenodo
Year: 2020

description: Task 2.2 within Work Package 2, of the SHERPA project is dedicated to the design, production and maintenance of an online stakeholder engagement support (OSES) tool for assisting SHERPA Facilitators and Monitors of Multi-ActorPlatforms (MAPs) during the duration of the project, and beyond. This toolbox is designed to offer hands-on guidance on methods and tools for stakeholder engagement. It is experience-based, tailored on the specific capacity and needs of its target users, easily accessible online through the project website, user-friendly, free, and is conceived to remain tuned on the needs of its users. The toolbox is available on the website: https://rural-interfaces.eu/resources-and-tools/stakeholder-engagement-tools/
Phase diffusion in graphene-based Josephson junctions
Creators: name: Borzenets, I. V.
name: Coskun, U. C.
name: Jones, S. J.
name: Finkelstein, G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report on graphene-based Josephson junctions with contacts made from lead. The high transition temperature of this superconductor allows us to observe the supercurrent branch at temperatures up to $\sim 2$ K, at which point we can detect a small, but non-zero, resistance. We attribute this resistance to the phase diffusion mechanism, which has not been yet identified in graphene. By measuring the resistance as a function of temperature and gate voltage, we can further characterize the nature of electromagnetic environment and dissipation in our samples.
description: 4 pages, 3 figures, PRL
Characterisation of Triple Negative Breast Cancer biomarkers identified using DNA-Aptamers
Creators: name: MARSHALL, MORGAN LOUISE
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified

description: This thesis focuses on identifying new drug targets for triple-negative breast cancer (TNBC), which is a chemotherapy-resistant and highly aggressive type of breast cancer. Because it has limited targeted therapies TNBC patients tend to succumb to the disease within 5 years of diagnosis. Using small pieces of tumour-targeting DNA called aptamers, this study identified seven new possible TNBC drug targets, and shows that targeting or inhibiting the correct function of the proteins alpha-enolase or stratifin may be useful for the development of extremely specific tumour cell targeted therapies that reduce the aggression of TNBC tumours.
The inositol polyphosphate 5-phosphatase INPP5K regulates energy metabolism via skeletal muscle
Creators: name: LE, KAI QIN
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 310103
subject: Cell metabolism

description: This thesis reveals that an enzyme involved in the dynamic regulation of phosphoinositides plays a critical role in regulating systemic energy metabolism via regulating skeletal muscle energy metabolism. This suggests that manipulation of this enzyme may be developed as a promising therapeutic strategy for the treatment of metabolic disorders.
Blockchain in the Logistics of Health Technologies
Creators: name: Georgiev, Svetlin
name: Priftis, Stamatios
name: Grigorov, Evgeni
Publisher: name: figshare
Year: 2021
Subjects: subject: 140208 Health Economics
subject: FOS: Economics and business
subject: Health Care

description: act. The article focuses on the practical significance of blockchain technology and its contributions to public health. The focus is on innovations in the sphere of logistics such as smart contracts and “Internet of things” that illustrate their contribution to achieving quality and transparent logistics of health technology management. The methodology of the article includes monitoring technological innovation in logistics. It is based on literary search, tracking development trends, and the importance of blockchain technology in various health care areas. Innovation in logistics finds its place and role in activities aimed at protecting public health. Blockchain contributes to increasing trust between health logistics and service providers, ensuring a secure production process and flexibility in the distribution chain.
Modeling the near-UV band of GK stars, Paper II: NLTE models
Creators: name: Short, C. Ian
name: Campbell, Eamonn A.
name: Pickup, Heather
name: Hauschildt, Peter H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a grid of atmospheric models and synthetic spectral energy distributions (SEDs) for late-type dwarfs and giants of solar and 1/3 solar metallicity with many opacity sources computed in self-consistent Non-Local Thermodynamic Equilibrium (NLTE), and compare them to the LTE grid of Short & Hauschildt (2010) (Paper I). We describe, for the first time, how the NLTE treatment affects the thermal equilibrium of the atmospheric structure (T(tau) relation) and the SED as a finely sampled function of Teff, log g, and [A/H] among solar metallicity and mildly metal poor red giants. We compare the computed SEDs to the library of observed spectrophotometry described in Paper I across the entire visible band, and in the blue and red regions of the spectrum separately. We find that for the giants of both metallicities, the NLTE models yield best fit Teff values that are ~30 to 90 K lower than those provided by LTE models, while providing greater consistency between \log g values, and, for Arcturus, Teff values, fitted separately to the blue and red spectral regions. There is marginal evidence that NLTE models give more consistent best fit Teff values between the red and blue bands for earlier spectral classes among the solar metallicity GK giants than they do for the later classes, but no model fits the blue band spectrum well for any class. For the two dwarf spectral classes that we are able to study, the effect of NLTE on derived parameters is less significant.
description: Submitted to The Astrophysical Journal. Observed spectrophotometric library, and grids of NLTE and LTE) synthetic spectra for GK stars available at http://www.ap.smu.ca/~ishort/PHOENIX
First-principles calculation of magnetoelastic coefficients and magnetostriction in the spinel ferrites CoFe2O4 and NiFe2O4
Creators: name: Fritsch, Daniel
name: Ederer, Claude
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present calculations of magnetostriction constants for the spinel ferrites CoFe2O4 and NiFe2O4 using density functional theory within the GGA+U approach. Special emphasis is devoted to the influence of different possible cation distributions on the B site sublattice of the inverse spinel structure on the calculated elastic and magnetoelastic constants. We show that the resulting symmetry-lowering has only a negligible effect on the elastic constants of both systems as well as on the magnetoelastic response of NiFe2O4, whereas the magnetoelastic response of CoFe2O4 depends more strongly on the specific cation arrangement. In all cases our calculated magnetostriction constants are in good agreement with available experimental data. Our work thus paves the way for more detailed first-principles studies regarding the effect of stoichiometry and cation inversion on the magnetostrictive properties of spinel ferrites.
description: 11 pages, 6 figures
Molecular mechanisms and inhibition of the Grb7 signalling protein in breast cancer
Creators: name: STURRE, NATASHA PAIGE
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 321101
subject: Cancer cell biology
classificationCode: 340407
subject: Proteins and peptides

description: Metastatic breast cancer is considered incurable, and the identification of new molecular targets is a field of interest. One possible therapeutic target is growth factor receptor bound protein 7 (Grb7). It was demonstrated when an aggressive phenotype is induced in breast cancer cell lines Grb7 expression increases. This thesis further demonstrated that the function of inhibitors targeting Grb7 could be restored through the addition and/or removal of amino acids. Finally, it was illustrated that Grb7 inhibition in combination with a chemotherapy, called doxorubicin, did not enhance breast cancer sensitivity to this anti-cancer agent. Other anti-cancer agents should be explored in combination with Grb7 inhibition.
Abstract: 3D Model Of Slip-Running Reconnection On Solar Sigmoidal Regions
Creators: name: Douglas, Brianna
Publisher: name: Zenodo
Year: 2015
Subjects: Magnetic reconnection
Coronal mass ejections

description: The structure of energy storing magnetic field lines on the Sun is very twisted and contorted. Some of the twist arises from photospheric foot point motion and some is due to currents carried into the corona as fields emerge. The stability of a region depends on both the energy stored (so-called “free” energy) and on the structure of the surrounding nearly potential fields. Free energy is usually contained in these S-shaped regions called sigmoids on the solar corona. The only way to reach lower energy state is to release this free energy, by changing its connectivity. This change in connectivity leads to flares and coronal mass ejections (CMEs) that can affect environments of nearby planets. For this project, we focus on a special kind of connectivity change called slip-running reconnection to create 3D numerical models of flare-producing magnetic fields. By comparing these numerical models to observational data from Atmospheric Imaging Assembly (AIA), we will be able to better explain the evolution of sigmoidal flares from active regions. We are studying a flare from  Dudik et al 2014 paper (2012 July 12), and a flare from 2015 June 14. Using the Coronal Modeling System (CMS) software, we read the photospheric magnetogram for the specified date and time, compute the potential field, setup the 3D flux rope path, and then relax this flux rope over 60,000 iterations to create a nonlinear force-free field (NLFFF). Using these relaxed models we find the best-fit loops surrounding the flux rope. We then compare these models to the observations in AIA. We compare the magnetic field structure in our models with the observed slipping. For regions near our inserted flux rope, our models successfully correlate with this observation. Further modeling is required, but these initial results suggest that NLFFF modeling may be able to capture realistic 3-D magnetic structures associated with slipping reconnection.
description: This work is supported by NSF-REU Solar Physics Program at SAO, grant number AGS 1263241 and AFOSR Grant Z15-12504 "Toward Improved Space Weather Prediction Through the Observation and Modeling of Coronal Magnetism".
Wolfram Prinz und Ronald G. Kecks, Das französische Schloß der Renaissance. Form und Bedeutung der Architektur, ihre geschichtlichen und gesellschaftlichen Grundlagen
Creators: name: Châtelet-Lange, Liliane
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Rezension zu: Wolfram Prinz und Ronald G. Kecks, Das französische Schloß der Renaissance. Form und Bedeutung der Architektur, ihre geschichtlichen und gesellschaftlichen Grundlagen. Mit Beiträgen von Uwe Albrecht und einem Beitrag von Jean Guillaume. Berlin, Gebr. Mann Verlag 1985. 646 Seiten mit 890 Abbildungen und 12 Farbtafeln. DM 390,-.
description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 39 Nr. 5 (1986): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Multi-Spacecraft Characterization Of Current Sheet Crossings In The Dynamic Solar Wind
Creators: name: Foster, Natalie
Publisher: name: Zenodo
Year: 2015
Subjects: Solar wind
Coronal mass ejection
Solar magnetic reconnection

description: The sun releases immense amounts of energy in the form of interplanetary coronal mass ejections (ICMEs) that can propagate through the solar wind towards Earth. Dragged along with it is a superconducting plasma of highly ionized gas that carries a “frozen-in” magnetic field. DSCOVR was recently launched and has joined Wind, ACE, and SOHO at L1 in order to make independent magnetic field measurements of the solar wind. These data, in conjunction with velocity measurements and the DSCOVR Faraday Cup ion spectra, can give us a sense of what shape the current sheets have as they pass through the spacecraft. Magnetic reconnection occurs as a result of the squeezing of opposing field lines to a cusp in a direction perpendicular to the direction of travel, and can continue to occur out to interplanetary distances due to the large amount of energy stored in ICME field lines. In particular, we are interested in high-density pile-up regions where the B-field components change sign during the June 22-23 ICME of this year. With at least three spacecraft, we are able to map the current sheet crossings in the solar wind at snapshots in time through planar timing calculations and minimum variance analysis. The advantages of multi-point and high time resolution plasma measurements will be assessed in determining large scale morphology, and for small scale dynamics of ICMEs, respectively.

Keywords: solar wind, coronal mass ejection, solar magnetic reconnection.
description: This work is supported under the NSF-REU solar physics program at SAO, grant number AGS-1263241, and Wind MODA (Mission Operations and Data Analysis) at NASA.
BIOREFINERY MANUAL: BENEFITS AND SUSTAINABILITY OF SEAWEED BIOREFINERY
Creators: name: Jouanneau Diane
name: Hanbidge Avril
name: Cascella Kévin
name: Potin Philippe
Publisher: name: Zenodo
Year: 2021
Subjects: seaweed biorefinery, sugar kelp, sea lettuce

description: This Biorefinery Manual is dedicated to explain the benefits and sustainability of seaweed biorefinery processes. It highlights the general methodology and innovations for effective implementation of each stage of the biorefinery process. It demonstrates good practices acquired during project implementation. 
Dynamics of end to end loop formation for an isolated chain in viscoelastic fluid
Creators: name: Chakrabarti, Rajarshi
Publisher: name: arXiv
Year: 2012
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We theoretically investigate the looping dynamics of a linear polymer immersed in a viscoelastic fluid. The dynamics of the chain is governed by a Rouse model with a fractional memory kernel recently proposed by Weber et al. (S. C. Weber, J. A. Theriot, and A. J. Spakowitz, Phys. Rev. E 82, 011913 (2010)). Using the Wilemski-Fixman (G. Wilemski and M. Fixman, J. Chem. Phys. 60, 866 (1974)) formalism we calculate the looping time for a chain in a viscoelastic fluid where the mean square displacement of the center of mass of the chain scales as t^(1/2). We observe that the looping time is faster for the chain in viscoelastic fluid than for a Rouse chain in Newtonian fluid up to a chain length and above this chain length the trend is reversed. Also no scaling of the looping time with the length of the chain seems to exist for the chain in viscoelastic fluid.
Tafeln
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 39 Nr. 5 (1986): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Design, Synthesis and Evaluation of Highly Selective AT2R Agonists
Creators: name: HIRMIZ, BAYDAA SEEZAR HIRMIZ
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified

description: High blood pressure is caused by the hormone angiotensin II and can lead to severe damage to the heart and other organs, called fibrosis. High blood pressure is often treated by blocking the angiotensin type 1 receptor (AT1R) but this cannot reverse fibrosis. By comparison, stimulation of the angiotensin type 2 receptor (AT2R) can reverse fibrosis, but there are very few such compounds. This Thesis used a novel approach to develop several lead compounds which bound strongly only to AT2R and showed long-lasting anti-fibrotic effects. This research now provides the basis for future drug development for the treatment of fibrosis.
Probing Energy Release Of Solar Flares Using Combined Radio, Euv, And X-Ray Observations
Creators: name: Prijatelj, Michael
Publisher: name: Zenodo
Year: 2015
Subjects: Solar flares
Solar magnetic reconnection
Solar radio emission

description: We investigate the release of magnetic energy stored within the solar atmosphere, the driving force and fundamental process behind solar flares. While it is widely accepted that the reconnection of magnetic field lines in the low solar corona powers solar flares, there is a dearth of direct information regarding the relative location of the magnetic energy release and the structure of the reconnecting magnetic fields. We utilize the Karl G. Jansky Very Large Array (VLA) to observe decimetric type III radio bursts produced during the impulsive phase of a C7.2 solar flare. The VLA’s unique observing technique of radio dynamic imaging spectroscopy enables trajectories of flare-accelerated electron beams to be derived as a function of time. Since these electron beams propagate along magnetic field lines in the low solar corona, we can use this method to trace newly reconnected coronal magnetic field lines in or around the reconnection region. Supported by multi-passband extreme ultraviolet imaging data from the SDO/AIA, photospheric magnetic field measurements from the SDO/HMI, and hard X-ray imaging data from RHESSI, we find that the accelerated electron beams first appear in the region trailing an erupting sigmoid which triggers the flare in question. We find our results to be generally consistent with the standard model of eruptive solar flares, in which magnetic energy is released via reconnection of antiparallel magnetic field lines trailing behind an erupting flux rope.
description: This work is supported by the NSF-REU Solar Physics Program at SAO, grant number AGS 1263241, and NASA contract SP02H1701R from Lockheed-Martin to SAO.
Quantum Logic and Geometric quantization
Creators: name: Camosso, Simone
Publisher: name: figshare
Year: 2021
Subjects: subject: 10107 Mathematical Logic, Set Theory, Lattices and Universal Algebra
subject: FOS: Mathematics

description: We assume that M is a phase space and H an Hilbert space yielded by a quantization scheme. In this paper we consider the set of all “experimental propositions” of M and we look for a model of quantum logic in relation to the quantization of the base manifold M. In particular we give a new interpretation about previous results of the author in order to build an “asymptotic quantum probability space” for the Hilbert lattice L(H).
Die webetechnischen Ergebnisse bei der Untersuchung des Tuches aus dem Moore bei Neddenaverbergen
Creators: name: Niehoff, H. F.
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2020

description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 2 (1928): Nachrichten aus Niedersachsens Urgeschichte
POKER: Estimating the power spectrum of diffuse emission with complex masks and at high angular resolution
Creators: name: Ponthieu, Nicolas
name: Grain, Julien
name: Lagache, Guilaine
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We describe the implementation of an angular power spectrum estimator in the flat sky approximation. POKER (P. Of k EstimatoR) is based on the MASTER algorithm developped by Hivon and collaborators in the context of CMB anisotropy. It works entirely in discrete space and can be applied to arbitrary high angular resolution maps. It is therefore particularly suitable for current and future infrared to sub-mm observations of diffuse emission, whether Galactic or cosmological.
description: Astronomy and Astrophysics, in press
An alternative proof of Hill's criterion of freeness for abelian groups
Creators: name: Macías-Díaz, J. E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: 20K20, 03E75, 20K25

description: In this note, we provide a different proof of Hill's criterion of freeness for abelian groups. Our proof hinges on the construction of suitable families of subgroups of the links in Hill's theorem and, ultimately, on the construction of such a family of pure subgroups of the group itself.
Elucidating the molecular mechanisms of T cell-mediated hypersensitivity towards Beta-lactam antibiotics
Creators: name: GOH, SHAWN JUN RONG
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 320404
subject: Cellular immunology
classificationCode: 320401
subject: Allergy
subject: FOS: Clinical medicine
classificationCode: 320506
subject: Medical biochemistry - proteins and peptides (incl. medical proteomics)

description: Penicillin is a class of beta-lactam antibiotics that play an important role in combatting bacterial infections. Unfortunately, T cell mediated hypersensitivities towards penicillin is not well understood and patients with such allergies prevent clinicians from administrating this essential drug. My thesis describes a novel target of penicillin that plays a role in penicillin-induced T cell mediated allergies. This discovery will aid in understanding how T cells interact with penicillin to cause allergic reactions, and can be formulated into tools for screening protocols to prevent penicillin-induced hypersensitivities.
Modelling gravity on a hyper-cubic lattice
Creators: name: Tate, Kyle
name: Visser, Matt
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present an elegant and simple dynamical model of symmetric, non-degenerate (n x n) matrices of fixed signature defined on a n-dimensional hyper-cubic lattice with nearest-neighbor interactions. We show how this model is related to General Relativity, and discuss multiple ways in which it can be useful for studying gravity, both classical and quantum. In particular, we show that the dynamics of the model when all matrices are close to the identity corresponds exactly to a finite-difference discretization of weak-field gravity in harmonic gauge. We also show that the action which defines the full dynamics of the model corresponds to the Einstein-Hilbert action to leading order in the lattice spacing, and use this observation to define a lattice analogue of the Ricci scalar and Einstein tensor. Finally, we perform a mean-field analysis of the statistical mechanics of this model.
description: 5 pages
Adaptation-Based Programming in Haskell
Creators: name: Bauer, Tim
name: Erwig, Martin
name: Fern, Alan
name: Pinto, Jervis
Publisher: name: arXiv
Year: 2011
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences
subject: D.3.3

description: We present an embedded DSL to support adaptation-based programming (ABP) in Haskell. ABP is an abstract model for defining adaptive values, called adaptives, which adapt in response to some associated feedback. We show how our design choices in Haskell motivate higher-level combinators and constructs and help us derive more complicated compositional adaptives. We also show an important specialization of ABP is in support of reinforcement learning constructs, which optimize adaptive values based on a programmer-specified objective function. This permits ABP users to easily define adaptive values that express uncertainty anywhere in their programs. Over repeated executions, these adaptive values adjust to more efficient ones and enable the user's programs to self optimize. The design of our DSL depends significantly on the use of type classes. We will illustrate, along with presenting our DSL, how the use of type classes can support the gradual evolution of DSLs.
description: In Proceedings DSL 2011, arXiv:1109.0323
Improved Ray Trace Program For Deformed X-Ray Optical Systems
Creators: name: Thordarson, Bakhita
Publisher: name: Zenodo
Year: 2015
Subjects: X-Ray Optics
Ray trace
Astronomical optics

description: The current program that exists to ray trace deformed optical systems has become obsolete with time and system upgrades. Previously written in Fortran, a similar program has been written in Matlab. This program, however, has some limits. By rewriting certain sections, the processing rate has increased by a factor of five and the program has been adapted to use input from the new FEA software. We can now run new optical designs through the ray trace program and find the optical performance of both the perfect surface and an approximation of the deformed surface. We have made progress towards reducing the approximation using a method different from Newtonian iteration. Future development will work towards improving on the approximation, focusing on moving from a successful system with one mirror, to a successful system with multiple mirrors.
description: This work is supported under contract NNM13AA40C from NASA to SAO.
Existence of wave operators with time-dependent modifiers for the Schödinger equations with long-range potentials on scattering manifolds
Creators: name: Itozaki, Shinichiro
Publisher: name: arXiv
Year: 2012
Subjects: subject: Analysis of PDEs (math.AP)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 58J50 (Primary) 81U05 (Secondary)

description: We construct time-dependent wave operators for Schrödinger equations with long-range potentials on a manifold $M$ with asymptotically conic structure. We use the two space scattering theory formalism, and a reference operator on a space of the form $\mathbb{R} \times \partial M$, where $\partial M$ is the boundary of $M$ at infinity. We construct exact solutions to the Hamilton-Jacobi equation on the reference system $\mathbb{R} \times \partial M$, and prove the existence of the modified wave operators.
description: 27 pages
Tracing The Prevalent Small-Scale Transition Region Jets Observed With Iris To Coronal Structures
Creators: name: Wendeln, Carolyn
Publisher: name: Zenodo
Year: 2015
Subjects: Solar wind
Solar corona
Coronal plumes
Transition region

description: The transition region, the interface between the chromosphere and corona, is dominated by network-like emission and magnetic field structures. Observations from  the Interface Region Imaging Spectrograph (IRIS) reveal the prevalence of small-scale, jet-like features with temperatures of about 0.1 million degrees from network structures. These network jets have been suggested to be supersonic mass flows and may play an important role in transporting mass and energy to the corona and solar wind. Furthermore, EUV imaging observations reveal outward-propagating disturbances within coronal plumes originating from network regions. Previous investigations are inconclusive about the nature of these propagating disturbances. Some works suggest they are upward propagating slow magnetoacoustic waves, while others suggest they are coronal mass flows rather than waves.  We present the first comparative study between coronal propagating disturbances observed in the AIA 171 Å (Fe X/Fe IX)  passband and transition region network jets observed in IRIS 1330 Å (C II) slit-jaw images. By relating these two features, we seek further insight into the nature of coronal propagating disturbances and ultimately into the energy and mass transfer between the transition region, corona, and solar wind. Our preliminary study  indicates that network jets and coronal propagating disturbances are spatially correlated, suggesting that coronal propagating disturbances could be either waves triggered by network jets or the coronal continuations of those mass flows outward into the solar wind. Our continuing investigation will focus on disambiguating these two scenarios by characterizing the temporal and structural relationship between these coronal propagating disturbances and associated network jets.
description: This work was supported by the NSF-REU Solar Physics Program at SAO, grant number AGS 1263241; grant number NNX15AF48G from NASA to SAO; and by the IRIS contract 8100002705 from Lockheed-Martin to SAO.
Insight into the mechanisms exploited by daptomycin resistant Staphylococcus aureus to evade innate Dendritic Cell Responses
Creators: name: JAHAN, NAZNEEN
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 320407
subject: Innate immunity

description: This thesis focuses on the immune cell response to an antibiotic resistant pathogen. Specifically, it investigates the molecular mechanisms that contribute to the immune recognition of antibiotic resistant Staphylococcus aureus infection by dendritic cells. This thesis also identifies immunostimulatory agents that can improve immune responses to antibiotic resistant pathogens.
Building Big Flares: Constraining Generating Processes Of Solar Flare Distributions
Creators: name: Wyse Jackson, Thomas
Publisher: name: Zenodo
Year: 2015
Subjects: subject: Sun
subject: Solar flares
subject: Statistics
subject: FOS: Mathematics
subject: Self-organized criticality

description: We address mechanisms which seek to explain the observed solar flare distribution, dN/dE ~ E1.8. We have compiled a comprehensive database, from GOES, NOAA, XRT, and AIA data, of solar flares and their characteristics, covering the year 2013. These datasets allow us to probe how stored magnetic energy is released over the course of an active region’s evolution. We fit power-­‐‑laws to flare distributions over various attribute groupings. For instance, we compare flares that occur before and after an active region reaches its maximum area, and show that the corresponding flare distributions are indistinguishable; thus, the processes that lead to magnetic reconnection are similar in both cases. A turnover in the distribution is not detectable at the energies accessible to our study, suggesting that a self-organized critical (SOC) process is a valid mechanism. However, we find changes in the distributions that suggest that the simple picture of an SOC where flares draw energy from an inexhaustible reservoir of stored magnetic energy is incomplete. Following the evolution of the flare distribution over the lifetimes of active regions, we find that the distribution flattens with time, and for larger active regions, and that a single power-­law model is insufficient. This implies that flares that occur later in the lifetime of the active region tend towards higher energies. We conclude that the SOC process must have an upper bound. Increasing the scope of the study to include data from other years and more instruments will increase the robustness of these results.
description: This work was supported by the NSF-REU Solar Physics Program at SAO, grant number AGS 1263241, NASA Contract NAS8-03060 to the Chandra X-ray Center and by NASA Hinode/XRT contract NNM07AB07C to SAO
Investigating the molecular basis for specific and cross-reactive T cell responses in Celiac Disease
Creators: name: CIACCHI, LAURA
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 310803
subject: Plant cell and molecular biology
classificationCode: 310902
subject: Animal cell and molecular biology
classificationCode: 310199
subject: Biochemistry and cell biology not elsewhere classified
classificationCode: 320599
subject: Medical biochemistry and metabolomics not elsewhere classified
classificationCode: 340202
subject: Crystallography
classificationCode: 320499
subject: Immunology not elsewhere classified

description: Celiac disease is triggered by ingestion of gluten from wheat, rye and barley in genetically susceptible patients. In the western population, only 1% of individuals develop celiac disease despite 35% being genetically predisposed. This suggests that environmental exposure plays a role in aetiology of disease. This thesis links bacterial exposure with celiac disease as patients could recognise molecular mimics of gluten derived from Pseudomonas species. We uncovered the mechanism behind immune cell recognition of wheat-gluten peptides and bacterially-derived molecular mimics of these peptides. Future efforts to target key interactions identified in this study may offer therapeutic benefit.
Demografischer Wandel - Japans Strategien
Creators: name: Feifel, Maximilian
Publisher: name: Freie Universität Berlin
Year: 2015
Subjects: subject: Demografie
subject: Demografischer Wandel
subject: Japan
subject: Strukturwandel
subject: Sozialpolitik
subject: Migration
subject: Arbeitsimmigration
subject: Technologie
subject: demographic change
subject: population study
subject: structural change
subject: welfare policy
subject: migration
subject: work Immigration
subject: technology
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie

description: Der demografische Wandel beschleunigt sich allmählich. Als eine der wichtigsten gesellschaftlichen Entwicklungen unseres Jahrhunderts charakterisieren ihn zunehmend deutliche Verschiebungen in vielen Bevölkerungsstrukturen. Dies stellt immer mehr Länder vor eine Reihe unterschiedlicher Herausforderungen. Nicht nur wirkungsstarke sozialpolitische Konsequenzen können mittlerweile abgesehen werden. Viele Fakten sprechen dafür, dass der demografische Wandel auch einen tief liegenden makroökonomischen Strukturwandel hervorrufen wird. In Japan ist die Veränderung durch den demografischen Wandel besonders fortgeschritten und intensiv. Sie ist in weiten Teilen zudem charakteristisch für die Umwälzungen, die auf viele andere Industriestaaten in absehbarer Zeit zukommen werden. In der vorliegenden Arbeit wird mit dem Ansatz der wissenschaftlichen Zukunftsforschung ein Bogen von der internationalen Dimension des demografischen Wandels über die extremen Ausprägungen in Japan bis hin zu einzelnen Strategien der japanischen Regierung gespannt. Es wird aufgezeigt, warum das Zusammenspiel der drei demografischen Variablen Geburtenrate, Lebenserwartung und Migration in Japan zu einem Ungleichgewicht führt, und befunden, dass die verfolgten strategischen Ansätze um dieses Ungleichgewicht auszugleichen bisher noch deutlich zu kurz greifen.
Die römisch-deutsche Königin im spätmittelalterlichen Verfassungswandel
Creators: name: Dick, Stefanie
Publisher: name: Vorträge und Forschungen
Year: 2020

description: Vorträge und Forschungen, Bd. 84 (2017): Vorträge und Forschungen: Die mittelalterliche Thronfolge im europäischen Vergleich
D2.4 Social Media channels
Creators: name: Mwemena, Prody
name: Nieto, Enrique
Publisher: name: Zenodo
Year: 2019

description: This document presents the links to all the SHERPA social media accounts, to fulfil the requirements foreseen in the Work Package 2. Further information about the strategic use of each of the Social Media accounts presented in this document is described in the D2.1 Strategy for project Stakeholder Engagement, Communication and Dissemination.
Low energy graphene edge termination via small diameter nanotube formation
Creators: name: Ivanovskaya, Viktoria V.
name: Zobelli, Alberto
name: Wagner, Philipp
name: Heggie, Malcolm I.
name: Briddon, Patrick R.
name: Rayson, Mark J.
name: Ewels, Chris P.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We demonstrate that free graphene sheet edges can curl back on themselves,reconstructing as nanotubes. This results in lower formation energies than any other non-functionalised edge structure reported to date in the literature. We determine the critical tube size and formation barrier and compare with density functional simulations of other edge terminations including a new reconstructed Klein edge. Simulated high resolution electron microscopy images show why such rolled edges may be difficult to detect. Rolled zigzag edges serve as metallic conduction channels, separated from the neighbouring bulk graphene by a chain of insulating sp$^3$-carbon atoms, and introduce Van Hove singularities into the graphene density of states.
description: To appear in Phys. Rev. Lett
Gap opening and orbital modification of superconducting FeSe above the structural distortion
Creators: name: Wen, Y. -C.
name: Wang, K. -J.
name: Chang, H. -H.
name: Luo, J. -Y.
name: Shen, C. -C.
name: Liu, H. -L.
name: Sun, C. -K.
name: Wang, M. -J.
name: Wu, M. -K.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We utilize steady-state and transient optical spectroscopies to examine the responses of nonthermal quasiparticles with respect to orbital modifications in normal-state iron-chalcogenide superconductors. The dynamics shows the emergence of gap-like quasiparticles (associated to a ~36 meV energy gap) with a coincident transfer of the optical spectral weight in the visible range, at temperatures above the structural distortion. Our observations suggest that opening of the high-temperature gap and the lattice symmetry breaking are possibly driven by short-range orbital and/or charge orders, implicating a close correlation between electronic nematicity and precursor order in iron-based superconductors.
Role of Neisseria gonorrhoeae secreted outer membrane vesicles in immune evasion
Creators: name: Dhital, Subhash
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 320407
subject: Innate immunity
classificationCode: 320701
subject: Medical bacteriology

description: Neisseria gonorrhoeae is a bacterial pathogen that causes gonorrhea, a sexually transmitted infection. Infections can remain asymptomatic or lead to several inflammatory diseases. The thesis is focused on how our immune system senses and responds to pathogenic Neisseria. By using clinical isolates of Neisseria gonorrhoeae, the thesis identified extracellular vesicles released by the bacteria to affect the initial response of the immune system. These responses change depending on the bacterial strain used. This has improved our understanding how the immune system responds to pathogenic Neisseria and open up new avenues to dampen excessive inflammation.
The Role of DOT1L in B-Cell Biology
Creators: name: KEALY, LIAM CHRISTOPHER
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 320404
subject: Cellular immunology
classificationCode: 310102
subject: Cell development, proliferation and death
classificationCode: 320405
subject: Humoural immunology and immunochemistry
classificationCode: 310504
subject: Epigenetics (incl. genome methylation and epigenomics)

description: This thesis examined the role of the histone lysine 79 methyltransferase, DOT1L, in the regulation of B-cell biology. We showed that DOT1L is playing a key role in the early development of B-lymphocytes and in the V(D)J recombination events that establish a diverse B-cell receptor repertoire. In addition to this, we revealed a critical role for DOT1L in the formation and regulation of the germinal centre reaction via H3K79 methylation of key target genes. In this way, DOT1L plays a vital role in establishing effective and lasting humoral immunity to vaccination and infection and in regulating different stages of B-cell biology.
Weighted Patterns as a Tool for Improving the Hopfield Model
Creators: name: Karandashev, Iakov
name: Kryzhanovsky, Boris
name: Litinskii, Leonid
Publisher: name: arXiv
Year: 2012
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Machine Learning (cs.LG)
subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We generalize the standard Hopfield model to the case when a weight is assigned to each input pattern. The weight can be interpreted as the frequency of the pattern occurrence at the input of the network. In the framework of the statistical physics approach we obtain the saddle-point equation allowing us to examine the memory of the network. In the case of unequal weights our model does not lead to the catastrophic destruction of the memory due to its overfilling (that is typical for the standard Hopfield model). The real memory consists only of the patterns with weights exceeding a critical value that is determined by the weights distribution. We obtain the algorithm allowing us to find this critical value for an arbitrary distribution of the weights, and analyze in detail some particular weights distributions. It is shown that the memory decreases as compared to the case of the standard Hopfield model. However, in our model the network can learn online without the catastrophic destruction of the memory.
description: 19 pages, 17 figures
Targeting cancer-associated fibroblast differentiation to improve anti-tumour immune responses
Creators: name: ABUWARWAR, MOHAMMED HASSAN Y
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 321101
subject: Cancer cell biology
classificationCode: 320409
subject: Tumour immunology

description: Immunotherapy enables a patient’s own immune system to attack the disease. However, not every cancer patient responds to this type of therapy. This thesis discovered new ways of targeting cancers which may yield promising immunotherapy outcomes.
Role of proteolytic processing of the Helicobacter pylori vacuolating cytotoxin,VacA, in toxin activity
Creators: name: Mahmud, Toslim
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 320599
subject: Medical biochemistry and metabolomics not elsewhere classified
classificationCode: 320799
subject: Medical microbiology not elsewhere classified

description: Helicobacter pylori is a causative agent of gastritis, peptic ulcer, and gastric cancer. Vacuolating Cytotoxin A (VacA) is a major virulence factor of the bacteria, which is directly involved in disease causation. VacA mode of action, and how this action correlates with cancer development, has been poorly understood for the last three decades since its discovery. My research provided insight into VacA disease-associated activation inside host-cells, and which parts of VacA are involved in this activation. These findings highlight novel perspectives of VacA activity that enhance our future opportunities for discovering effective therapeutics against VacA-associated disease.
Dust release and tensile strength of the non-volatile layer of cometary nuclei
Creators: name: Skorov, Yuri
name: Blum, Jürgen
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We developed a thermophysical model for cometary nuclei, which is based upon the assumption that comets form by the gravitational instability of an ensemble of dust and ice aggregates. Under this condition, the tensile strength of the ice-free outer layers of a cometary nucleus can be calculated, using the dust-aggregate collision and adhesion model of Weidling et al. (2011). Based on available laboratory data on the gas permeability and thermal conductivity of ice-free dust layers, we derived the temperature and pressure at the dust-ice interface for pure water and pure carbon dioxide ice. Comparison of the vapor pressure below the dust crust with its tensile strength allows the prediction of dust release from cometary surfaces. Our model predicts dust activity for pure CO2 ice and for heliocentric distances of
Pulsed rotating supersonic source used with merged molecular beams
Creators: name: Sheffield, L.
name: Hickey, M.
name: Krasovitskiy, V.
name: Rathnayaka, K. D. D.
name: Lyuksyutov, I. F.
name: Herschbach, D. R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We describe a pulsed rotating supersonic beam source, evolved from an ancestral device [M. Gupta and D. Herschbach, J. Phys. Chem. A 105, 1626 (2001)]. The beam emerges from a nozzle near the tip of a hollow rotor which can be spun at high-speed to shift the molecular velocity distribution downward or upward over a wide range. Here we consider mostly the slowing mode. Introducing a pulsed gas inlet system, cryocooling, and a shutter gate eliminated the main handicap of the original device, in which continuous gas flow imposed high background pressure. The new version provides intense pulses, of duration 0.1-0.6 ms (depending on rotor speed) and containing ~10^12 molecules at lab speeds as low as 35 m/s and ~ 10^15 molecules at 400 m/s. Beams of any molecule available as a gas can be slowed (or speeded); e.g., we have produced slow and fast beams of rare gases, O2, Cl2, NO2, NH3, and SF6. For collision experiments, the ability to scan the beam speed by merely adjusting the rotor is especially advantageous when using two merged beams. By closely matching the beam speeds, very low relative collision energies can be attained without making either beam very slow.
description: 26 pages, 10 figures
Variational Method for the Three-Dimensional Many-Electron Dynamics of Semiconductor Quantum Wells
Creators: name: Haas, F.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The three-dimensional nonlinear dynamics of an electron gas in a semiconductor quantum well is analyzed in terms of a self-consistent fluid formulation and a variational approach. Assuming a time-dependent localized profile for the fluid density and appropriated spatial dependences of the scalar potential and fluid velocity, a set of ordinary differential equations is derived. In the radially symmetric case, the prominent features of the associated breathing mode are characterized.
A Domain-Specific Language for Incremental and Modular Design of Large-Scale Verifiably-Safe Flow Networks (Preliminary Report)
Creators: name: Bestavros, Azer
name: Kfoury, Assaf
Publisher: name: arXiv
Year: 2011
Subjects: subject: Programming Languages (cs.PL)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Logic in Computer Science (cs.LO)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: We define a domain-specific language (DSL) to inductively assemble flow networks from small networks or modules to produce arbitrarily large ones, with interchangeable functionally-equivalent parts. Our small networks or modules are "small" only as the building blocks in this inductive definition (there is no limit on their size). Associated with our DSL is a type theory, a system of formal annotations to express desirable properties of flow networks together with rules that enforce them as invariants across their interfaces, i.e, the rules guarantee the properties are preserved as we build larger networks from smaller ones. A prerequisite for a type theory is a formal semantics, i.e, a rigorous definition of the entities that qualify as feasible flows through the networks, possibly restricted to satisfy additional efficiency or safety requirements. This can be carried out in one of two ways, as a denotational semantics or as an operational (or reduction) semantics; we choose the first in preference to the second, partly to avoid exponential-growth rewriting in the operational approach. We set up a typing system and prove its soundness for our DSL.
description: In Proceedings DSL 2011, arXiv:1109.0323