cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Rovnoscydmus
Creators: name: Jałoszyński, Paweł
name: Perkovsky, Evgeny
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Rovnoscydmus

description: † Rovnoscydmus sp. specimen 9
(Figs 22, 161–164)
Material studied. Late Eocene of Europe, Rovno amber: male; inclusion in elongate, subtriangular prism of amber 23.5 mm long (Fig. 22), collection number K-3322 (SIZK).
Description. Body (Figs 161–164) elongate, slender and relatively strongly convex, brown; BL 1.10 mm.
Head (Figs 161–164) visible only in lateral view, HL 0.23 mm; only sides of vertex and frons visible; compound eyes large, strongly convex, bean-shaped; tempora slightly shorter than eyes. Punctures on frons and vertex not visible; setae (Fig. 163) sparse, short and suberect. Antennae (Figs 161–164) slightly shorter than half BL, AnL 0.53 mm, antennal club not demarcated; antennomeres I–II strongly elongate, III–VII elongate (III only slightly), VIII–X about as long as broad or slightly transverse, XI much shorter than IX–X combined, about 1.6 × as long as broad, with rounded apex.
Pronotum (Figs 161–164) visible only in lateral view, broadest site not possible to define; PL 0.28 mm, punctures and setae poorly visible.
Elytra (161–164) elongate oval, strongly convex, broadest site not possible to define, EL 0.60 mm, punctures and setae poorly visible.
Legs (Figs 161–164) moderately long, slender, unmodified.
Remarks. This specimen is visible only in lateral view, but its measurements and proportions are similar to those of Rovnoscydmus species, the metacoxae are clearly separated from sides of metaventrite (Fig. 164), and the antennae are very similar to those of Rovnoscydmus frontalis. Examination in slightly lateroventral view revealed that the metaventral intercoxal process does not differ from that of Rovnoscydmus frontalis. Taking into account the shape of the head in lateral view very similar to that illustrated in Figs 124, 138 and 150, determination of the inclusion K-3322 as congeneric with Rovnoscydmus seems strongly supported.
A unique feature of this specimen is the aedeagus (AeL 0.30 mm) protruding from the abdomen (Figs 161– 164). It demonstrates that Rovnoscydmus has the male copulatory organ typical for most Glandulariini, i.e., with slender parameres visible at both sides of the median lobe; it also seems to be symmetrical. Moreover, as this is the only unambiguously identified male of this genus, it also demonstrates that at least in this species of Rovnoscydmus no peculiar external secondary sexual characters exist.
description: Published as part of Jałoszyński, Paweł & Perkovsky, Evgeny, 2016, Diversity of Scydmaeninae (Coleoptera: Staphylinidae) in Upper Eocene Rovno amber, pp. 1-85 in Zootaxa 4157 (1) on pages 52-53, DOI: 10.11646/zootaxa.4157.1.1, http://zenodo.org/record/262413
Narrative CV assessment
Creators: name: Hoogstraat, Robbert
Publisher: name: Zenodo
Year: 2023
Subjects: Narrative cv
Research assessment
Evidence based cv
Research proposals

description: Presentation about the assessment of narrative styled CV's at the Dutch Research Council (NWO: Nederlandse organisatie voor Wetenschappelijk Onderzoek) given by Robbert Hoogstraat for a workshop hosted by the Research Council of Norway.
description: {"references": ["Frank, Michael C. 'N-Best Evaluation for Academic Hiring and Promotion'. Trends in Cognitive Sciences 23, nr. 12 (december 2019): 983-85. https://doi.org/10.1016/j.tics.2019.09.010."]}
title: Two-year quality of life after robot-assisted radical prostatectomy according to pentafecta criteria and cancer of the prostate risk assessment (CAPRA-S)
Creators: name: Karagiotis, Theodoros
name: Witt, Jörn Hinrich
name: Jankowski, Thomas
name: Mendrek, Mikolaj
name: Wagner, Christian
name: Schuette, Andreas
name: Liakos, Nikolaos
name: Rachubinski, Pawel Adam
name: Urbanova, Katarina
name: Oelke, Matthias
name: Kachanov, Mykyta
name: Leyh-Bannurah, Sami-Ramzi
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2023
Subjects: subject: 610 Medicine and health

description: The quality of life (QoL) of men with optimal outcomes after robot-assisted radical prostatectomy (RARP) is largely unexplored. Thus we assessed meaningful changes of QoL measured with the EORTC QLQ-C30 24 months after RARP according to postsurgical Cancer of the Prostate Risk Assessment score (CAPRA-S) and pentafecta criteria. 2871 prostate cancer (PCa) patients with completed EORTC QLQ-C30 were stratified according to CAPRA-S, pentafecta (erectile function recovery, urinary continence recovery, biochemical-recurrence-free survival (BFS), negative surgical margins) and 90-day Clavien–Dindo-complications (CDC) ≤ 3a. Multivariable logistic regression analyses (LRM) aimed to predict improvement of EORTC QoL. Mean preoperative QoL values did not significantly differ between CAPRA-S low- (LR) vs. high-risk (HR, 75.7 vs. 75.2; p = 0.7) and pentafecta vs. non-pentafecta groups (75.6 vs. 75.2; p = 0.6). After RARP, stable QoL rates for CAPRA-S LR vs. HR and pentafecta were 30, 26 and 30%, respectively. Corresponding improved QoL rates were 44, 32 and 47%. In LRM, CAPRA-S and pentafecta criteria were independent predictors of improved QoL. We conclude that most favourable combined outcomes after RARP might confer stable or even improved QoL but up to one third of patients might experience deterioration. This warrants further investigation how to capture the underlying cause and to address and potentially solve these perceived negative effects despite successful RARP.
description: Finanziert über die DEAL-Vereinbarung mit Wiley 2019-2022.
Synthesis and electron field emission of nanocrystalline diamond thin films grown from N2/CH4 microwave plasmas
Creators: name: Krauss, A.R.
name: Qin, L.-C.
name: Gruen, D.M.
name: Gnaser, H.
name: Zhou, D.
name: Corrigan, T.D.
name: Chang, R.P.H.
name: McCauley, T.G.
Publisher: name: American Institute of Physics Inc.
Year: 1997

description: Nanocrystalline diamond films have been synthesized by microwave plasma enhanced chemical vapor deposition using N2/CH4 as the reactant gas without additional H2. The nanocrystalline diamond phase has been identified by x-ray diffraction and transmission electron microscopy analyses. High resolution secondary ion mass spectroscopy has been employed to measure incorporated nitrogen concentrations up to 8 ×1020 atoms/cm3. Electron field emission measurements give an onset field as low as 3.2 V/μm. The effect of the incorporated nitrogen on the field emission characteristics of the nanocrystalline films is discussed.
Additional file 1: of Effects of norepinephrine and β2 receptor antagonist ICI 118,551 on whisker hair follicle mechanoreceptors dissatisfy Merkel discs being adrenergic synapses
Creators: name: Sonekatsu, Mayumi
name: Gu, Steven
name: Hirosato Kanda
name: Jianguo Gu
Publisher: name: Figshare
Year: 2019
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Figure S1. Effects of norepinephrine on rapidly RA, SA1 and SA2 impulses evoked by mechanical stimulation in whisker hair follicles. (DOCX 15 kb) A) Sample traces show RA impulses in the absence (control, top), presence of 5 mM NE (middle), and wash out of the drug (bottom). Inset in each panel shows impulses at an expanded time scale. B) Summary data (n = 6) of RA impulse numbers in the experiments illustrated in A. C) Sample traces show SA1 impulses in the absence (control, top), presence of 5 mM NE (middle), and wash out of the drug (bottom). D) Summary data (n = 5) of SA1 impulse numbers in dynamic phase (left) and static phase (right) in the experiments illustrated in C. E) Sample traces show SA2 impulses in the absence (control, top), presence of 5 mM NE (middle), and wash out of the drug (bottom). F) Summary data (n = 5) of SA2 impulse numbers in dynamic phase (left) and static phase (right) in the experiments illustrated in E. Impulses in each experiment was evoked by a 38-μm mechanical displacement. Norepinephrine (NE, 5 mM) was applied for 10 min in each test. Data represent Mean ± SEM, *p
MPEC 2023-U94 : 2023 TT28
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 TT28

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Molecular Density Functional Theory for water with liquid-gas coexistence and correct pressure
Creators: name: Jeanmairet, Guillaume
name: Levesque, Maximilien
name: Sergiievskyi, Volodymyr
name: Borgis, Daniel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The solvation of hydrophobic solutes in water is special because liquid and gas are almost at coexistence. In the common hypernetted chain approximation to integral equations, or equivalently in the homogenous reference fluid of molecular density functional theory, coexistence is not taken into account. Hydration structures and energies of nanometer-scale hydrophobic solutes are thus incorrect. In this article, we propose a bridge functional that corrects this thermodynamic inconsistency by introducing a metastable gas phase for the homogeneous solvent. We show how this can be done by a third order expansion of the functional around the bulk liquid density that imposes the right pressure and the correct second order derivatives. Although this theory is not limited to water, we apply it to study hydrophobic solvation in water at room temperature and pressure and compare the results to all-atom simulations. With this correction, molecular density functional theory gives, at a modest computational cost, quantitative hydration free energies and structures of small molecular solutes like n-alkanes, and of hard sphere solutes whose radii range from angstroms to nanometers. The macroscopic liquid-gas surface tension predicted by the theory is comparable to experiments. This theory gives an alternative to the empirical hard sphere bridge correction used so far by several authors.
description: 18 pages, 6 figures
311. Safety and efficacy of maintenance therapies for anti-neutrophil cytoplasmic antibody small-vessel vasculitis: A network meta-analysis
Creators: name: Bellos1, Ioannis
Publisher: name: Zenodo
Year: 2022
Subjects: Vasculitis
ANCA
Abstracts
Giant Cell Arthritis
MPA
GPA
EGPA
Takayasu
IgA vasculitis

description: Backgrounds/ Objectives: Over the past two decades, considerable progress has been made in maintaining remission in patients with anti-neutrophil cytoplasmic antibody (ANCA) vasculitis using a variety of medications, including rituximab, azathioprine, mycophenolate, methotrexate, and glucocorticoids. However, although survival has improved amatically over the last decades, relapse rates remain significant for certain patients, stressing the need for advocation of new therapeutic strategies. The aim of this study was to compare the efficacy and safety of different regimens used for maintenance of remission in patients with ANCA-vasculitis. Methods This network meta-analysis studied adult patients with ANCA-vasculitis in complete remission, who were maintained with various regimens, excluding patients with eosinophilic granulomatosis with polyangiitis, and those who have ended up in end-stage kidney disease. Outcomes of interest included relapse (any/major), relapse-free survival and adverse effects. PubMed, Scopus, Web of Science, CENTRAL, Clinicaltrials.gov and Google Scholar were systematically searched from inception. Results: Overall, the meta-analysis was based on 10 reports, describing the outcomes of 7 RCTs including 752 patients with ANCA-vasculitis. Compared to rituximab, relapse-free survival was significantly worse with the use of azathioprine (HR: 2.11, 95% CI: 1.19-3.74), methotrexate (HR: 2.51, 95% CI: 1.24-5.08) and mycophenolate mofetil (HR: 3.57, 95% CI:1.70-7.46). Compared to mycophenolate mofetil, better outcomes were estimated for azathioprine (HR: 0.59, 95% CI: 0.37-0.94), cyclophosphamide (HR: 0.39, 95% CI: 0.20-0.75) and leflunomide (HR: 0.30, 95% CI: 0.11-0.84). Compared to rituximab a higher relapse risk was estimated for azathioprine (OR: 2.15, 95% CI: 1.00-4.59) and mycophenolate mofetil (OR: 4.42, 95% CI: 1.63-11.94). A higher risk of major relapse was calculated for azathioprine (OR: 2.39, 95% CI: 1.10-5.19), methotrexate (OR: 3.18, 95% CI: 1.14-8.89) and mycophenolate mofetil (OR: 5.20, 95% CI: 1.65-16.37) compared to rituximab. The rates of serious adverse effects did not differ significantly among interventions. Conclusion: Rituximab appears predominant in maintaining remission in patients with ANCA-vasculitis with no cost in adverse events. Disclosure: None
Efficient estimation of high-dimensional multivariate normal copula models with discrete spatial responses
Creators: name: Nikoloulopoulos, Aristidis K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Methodology (stat.ME)
subject: Applications (stat.AP)
subject: Computation (stat.CO)
subject: FOS: Computer and information sciences
subject: 62H11, 62P12

description: The distributional transform (DT) is amongst the computational methods used for estimation of high-dimensional multivariate normal copula models with discrete responses. Its advantage is that the likelihood can be derived conveniently under the theory for copula models with continuous margins, but there has not been a clear analysis of the adequacy of this method. We investigate the small-sample and asymptotic efficiency of the method for estimating high-dimensional multivariate normal copula models with univariate Bernoulli, Poisson, and negative binomial margins, and show that the DT approximation leads to biased estimates when there is more discretisation. For a high-dimensional discrete response, we implement a maximum simulated likelihood method, which is based on evaluating the multidimensional integrals of the likelihood with randomized quasi Monte Carlo methods. Efficiency calculations show that our method is nearly as efficient as maximum likelihood for fully specified high-dimensional multivariate normal copula models. Both methods are illustrated with spatially aggregated count data sets, and it is shown that there is a substantial gain on efficiency via the maximum simulated likelihood method.
description: arXiv admin note: text overlap with arXiv:1304.0905
title: Химическая термодинамика и кинетика
Creators: name: Новгородский государственный университет имени Ярослава Мудрого
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2020

description: Сборник содержит материалы докладов, включенных в программу Десятой Международной научной конференции «Химическая термодинамика и кинетика», проходившей с 25 по 29 мая 2020 г. в г. Великий Новгород на базе Новгородского государственного университета имени Ярослава Мудрого.
Reimagining How We Plan Housing for the Gworls: Prioritizing Black Women Over Profits Through the Eyes of a Black Feminist Abolitionist
Creators: name: Anyangwe, Deanie
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Using Black feminist theory and a systems change framework, I analyze 1) two mental models, Manifest Destiny and White Supremacist Capitalist Patriarchy, that determine who is human and shape relationships and power dynamics between different groups of people, and 2) how these mental models prioritize capital amassment over the well-being Black women, through a history of resource deprivation using U.S. planning policies and practices with an explicit focus on housing.
Fractional Skyrmions and their molecules
Creators: name: Gudnason, Sven Bjarke
name: Nitta, Muneto
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study a Skyrme-type model with a quadratic potential for a field with $S^2$ vacua. We consider two flavors of the model, the first is the Skyrme model and the second has a sixth-order derivative term instead of the Skyrme term; both with the added quadratic potential. The model contains molecules of half Skyrmions, each of them is a global (anti-)monopole with baryon number 1/2. We numerically construct solutions with baryon numbers one through six, and find stable solutions which look like beads on rings. We also construct a molecule with fractional Skyrmions having the baryon numbers 1/3 + 2/3, by adding a linear potential term.
description: RevTeX: 36 pages, 20 figures; V2: comments and Fig. 7 added
Best Practices for Internal Communications to Improve Employee Engagement
Creators: name: Boehling, Sara
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: The purpose of this study is to recommend best practices for employee engagement through internal communications strategy. This study utilizes a survey of the communications preferences and habits of employees in a mid-size healthcare company, Premier Inc., recommendations from internal communications professionals, and standards from published communications professionals. It was discovered that many employees still preferred email communication over multimedia such as video or podcasts, though several professionals feel email is outdated. Additionally, Premier’s current strategy had good overall engagement with 88% of survey respondents feeling that they are least mostly informed about what’s happening in their company.  Overall communication strategy was found to work best in enhancing engagement when created around employees’ most-used platforms and channels and featuring their topics of concern such as company events and benefits, all with well-formatted text and webpages. In conclusion, the best method for creating an overall communications strategy is to choose the platforms that employees interact with the most on a daily basis (e.g., Microsoft Teams for Premier employees) and utilize those to increase employee engagement with internal communications and the company as a whole.
Six Years of Fermi-LAT and Multi-wavelength Monitoring of the Broad-Line Radio Galaxy 3C 120: Jet Dissipation at Sub-parsec Scales from the Central Engine
Creators: name: Tanaka, Y. T.
name: Doi, A.
name: Inoue, Y.
name: Cheung, C. C.
name: Stawarz, L.
name: Fukazawa, Y.
name: Gurwell, M. A.
name: Tahara, M.
name: Kataoka, J.
name: Itoh, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present multi-wavelength monitoring results for the broad-line radio galaxy 3C 120 in the MeV/GeV, sub-millimeter, and 43 GHz bands over six years. Over the past two years, Fermi-LAT sporadically detected 3C 120 with high significance and the 230 GHz data also suggest an enhanced activity of the source. After the MeV/GeV detection from 3C 120 in MJD 56240-56300, 43 GHz VLBA monitoring revealed a brightening of the radio core, followed by the ejection of a superluminal knot. Since we observed the gamma-ray and VLBA phenomena in temporal proximity to each other, it is naturally assumed that they are physically connected. This assumption was further supported by the subsequent observation that the 43 GHz core brightened again after a gamma-ray flare occurred around MJD 56560. We can then infer that the MeV/GeV emission took place inside an unresolved 43 GHz core of 3C 120 and that the jet dissipation occurred at sub-parsec distances from the central black hole, if we take the distance of the 43 GHz core from the central black hole as ~ 0.5 pc, as previously estimated from the time lag between X-ray dips and knot ejections (Marscher et al. 2002; Chatterjee et al. 2009). Based on our constraints on the relative locations of the emission regions and energetic arguments, we conclude that the gamma rays are more favorably produced via the synchrotron self-Compton process, rather than inverse Compton scattering of external photons coming from the broad line region or hot dusty torus. We also derived the electron distribution and magnetic field by modeling the simultaneous broadband spectrum.
description: 6 pages, 4 figures. Accepted by ApJL
WOMEN’S WORK: HOW A LACK OF BENEFITS AND PROTECTIONS ARE FAILING NC’S SERVICE WORKERS
Creators: name: Burgess, Sara
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: This thesis project examines the lack of access women in North Carolina’s service industry have to health insurance, maternity leave and protections against sexual violence. The package is delivered as three long-form journalistic articles that highlight these key issues through characters and narrative.
»Ich glaube an Gott den allmächtigen Vater«
Creators: name: Benedikt XVI., Papst
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 4 Nr. 1 (1975): Internationale katholische Zeitschrift Communio, Band 4, Heft 1
Counterintuitive effect of gravity on the heat capacity of a metal sphere: re-examination of a well-known problem
Creators: name: De Palma, Giacomo
name: Sormani, Mattia C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: A well-known high-school problem asking the final temperature of two spheres that are given the same amount of heat, one lying on a table and the other hanging from a thread, is re-examined. The conventional solution states that the sphere on the table ends up colder, since thermal expansion raises its center of mass. It is found that this solution violates the second law of thermodynamics and is therefore incorrect. Two different new solutions are proposed. The first uses statistical mechanics, while the second is based on purely classical thermodynamical arguments. It is found that gravity produces a counterintuitive effect on the heat capacity, and the new answer to the problem goes in the opposite direction of what traditionally thought.
description: Submitted to Am.J.Phys
"Gebt dem Kaiser, was des Kaisers ist ...!" (Mt 22,15-22). Predigt am 19./20. Oktober 1996 in Mössingen
Creators: name: Theobald, Michael
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 28 Nr. 2 (1997): Diakonia, Band 28, Heft 2
Gas flow in barred potentials
Creators: name: Sormani, Mattia C.
name: Binney, James
name: Magorrian, John
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We use a Cartesian grid to simulate the flow of gas in a barred Galactic potential and investigate the effects of varying the sound speed in the gas and the resolution of the grid. For all sound speeds and resolutions, streamlines closely follow closed orbits at large and small radii. At intermediate radii shocks arise and the streamlines shift between two families of closed orbits. The point at which the shocks appear and the streamlines shift between orbit families depends strongly on sound speed and resolution. For sufficiently large values of these two parameters, the transfer happens at the cusped orbit as hypothesised by Binney et al. over two decades ago. For sufficiently high resolutions the flow downstream of the shocks becomes unsteady. If this unsteadiness is physical, as appears to be the case, it provides a promising explanation for the asymmetry in the observed distribution of CO.
description: Accepted for publication in MNRAS
X-ray outbursts from a new transient in NGC 55
Creators: name: Jithesh, V.
name: Wang, Zhongxiang
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We report the outbursts from a newly discovered X-ray transient in the Magellanic-type, SB(s)m galaxy NGC 55. The transient source, XMMU J001446.81-391123.48, was undetectable in the 2001 \xmm{} and 2004 \chandra{} observations, but detected in a 2010 \xmm{} observation at a significance level of $9σ$ in the 0.3--8 keV energy band. The \xmm{} spectrum is consistent with a power law with photon index $Γ= 3.17^{+0.22}_{-0.20}$, but is better fit with a $kT_{in} = 0.70\pm0.06$\,keV disk blackbody. The luminosity was $\sim 10^{38}$\,erg\,s$^{-1}$, and the source displayed strong short-term X-ray variability. These results, combined with the hardness ratios of its emission, strongly suggest an X-ray binary nature for the source. The follow-up studies with \swift{} XRT observations revealed that the source exhibited recurrent outbursts with period about a month. The XRT spectra can be described by a power law ($Γ\sim 2.5$--2.9) or a disk blackbody ($kT_{in}\sim 0.8$--1.0\,keV), and the luminosity was in a range of 10$^{38}$--10$^{39}$\,erg\,s$^{-1}$, with no evidence showing any significant changes of the spectral parameters in the observations. Based on the X-ray spectral and temporal properties, we conclude that XMMU J001446.81-391123.48 is a new transient X-ray binary in NGC 55, which possibly contains a black hole primary.
description: Accepted for publication in MNRAS; Matched with accepted version; 6 Pages, 5 Figures, 2 Tables
305. Human Leukocyte Antigen Association in Azathioprine-induced ug Hypersensitivity Reactions in Patients with Anti-Neutrophil-Cytoplasmic-Antibody Associated Vasculitis.
Creators: name: Salehi1, Tania
Publisher: name: Zenodo
Year: 2022
Subjects: Vasculitis
ANCA
Abstracts
Giant Cell Arthritis
MPA
GPA
EGPA
Takayasu
IgA vasculitis

description: Background: ug hypersensitivity reactions (DHRs) account for 6-10% of all ug reactions and may be linked to specific human leukocyte antigen (HLA) genes, particularly class 1 HLA antigens. Azathioprine (AZA) is a therapeutic agent used in the management of Anti-Neutrophil Cytoplasmic Antibody (ANCA) associated vasculitis (AAV). Although infrequent, AZA induced DHRs can be life-threatening and have a reported incidence of up to 9% in AAV patients (1). Methods: We conducted a retrospective review on a cohort of AAV patients previously treated with, or currently on AZA maintenance therapy. Participants were categorised into those who had experienced AZA DHR and those who were AZA tolerant. High resolution HLA tissue typing was performed in both groups. The primary endpoint was identification of a HLA gene association with AZA DHRs in the context of AAV. Results: The class I HLA allele, HLA-C*06:02, was solely expressed in AZA DHR patients (33.3%), whilst no patient who tolerated AZA had this allele (0.0%). This yielded a positive predictive value of 100% for HLA-C*06:02 in predicting AZA DHR in AAV patients, negative predictive value of 66.7%, sensitivity of 33.3% and specificity of 100% (Table 1). Conclusion: HLA-C*06:02, a well-recognised susceptibility allele found in association with psoriasis (2), may predict the development of AZA-induced DHR in patients with AAV. Given the potentially life-threatening nature of such reactions, prospective screening for this HLA marker could be considered, with avoidance of AZA among those with HLA-C*06:02 and caution with AZA in those without the allele. Verification among a larger cohort of patients will be required to confirm this recommendation. Disclosures: None. References 1. Hessels AC, Sanders JSF, van de Ven A, Kroesen BJ, Lambeck AJA, Rutgers A, et al. Azathioprine Hypersensitivity Synome in a Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Patients. J Allergy Clin Immunol Pract. 2019;7(3):1004-9. 2. Chen L, Tsai TF. HLA-Cw6 and psoriasis. Br J Dermatol. 2018;178(4):854-62.
Initiativen und Kontaktadressen zur Armutsbekämpfung
Creators: name: Mette, Norbert
name: Schlagnitweit, Markus
name: Karrer, Leo
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 28 Nr. 2 (1997): Diakonia, Band 28, Heft 2
IMPROVING WORKPLACE DIVERSITY: AN ANALYSIS OF COAST GUARD RECRUITING STRATEGIES
Creators: name: Corcoran, Samantha
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Similar to all branches of the U.S. military currently, the Coast Guard is facing unprecedented recruiting challenges not seen in years. Furthermore, the organization desires to increase diversity of personnel by recruiting increased numbers of underrepresented minorities to serve. This goal comes as a challenge as the Coast Guard faces issues with overall mission awareness and obstacles that act as a barrier to enticing people toward enlisting in the service. This paper explores recruiting strategies used by military branches, law enforcement agencies, and private corporations with respect to attracting underrepresented minorities to their organizations. It then discusses how the Coast Guard can utilize the situational theory of publics for recruiting challenges, which leads to the two research questions: 1. What are the challenges of reaching potential recruits through social media? 2. What are the challenges of influencing potential recruits through in-person efforts? The research questions were addressed through a content analysis of the Coast Guard Recruiting Command’s Instagram page and a series of in-depth interviews with current Coast Guard recruiters located in an urban city, coastal area, and rural area. This leads to the findings which outlines key challenges to include external obstacles such as the increasing desire to attend college or post-secondary education after high school, the undesirability to go to boot camp or work with firearms, and fear of commitment. Internal obstacles found include burdensome medical processes, geographic instability, and lack of social media training. The findings result in a recruiting best-practices guide for recruiters to use for social media and in-person efforts. In all, the findings of this paper serve as starting point for Coast Guard recruiting challenges, with the ultimate goal of recruiting increased numbers of underrepresented minorities to the service.
A Deep Dive of Employee Voices’ Impact on NFL Crisis Communication Strategies During the Black Lives Matter Movement
Creators: name: French, Jesse
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: "The thesis project aims to fill the gap in the literature regarding player activism’s effect on organizational crisis response strategies. Previous research has examined the Black Lives Movement and the NFL. The gap in research came from the lack of research surrounding the players’ impact. Previously, there was not any research that factored players into the NFL’s response to Black Lives Matter. This allowed for this thesis to examine the players’ role in the NFL’s crisis response strategies. This thesis collected data including press releases, NFL team tweets, and press conferences. Through in-depth sentiment analysis, the researcher was able to find how the NFL players’ activism affected the NFL’s crisis response strategies during the 2020 Black Lives Matter movement.  

This research found a direct effect of player activism on the NFL’s crisis response strategy. Initially, the NFL would issue statements emphasizing peace and unity and avoiding the usage of the phrase “Black Lives Matter”. In June 2020, NFL Commissioner Roger Goodell issued a video acknowledging the league’s mistake in not supporting its players from the start. The major limitations of this study were the lack of data available on the social media platform Instagram, the magnitude of the topic, and the availability of content from 2020.  "
The double mass hierarchy pattern: simultaneously understanding quark and lepton mixing
Creators: name: Hollik, Wolfgang Gregor
name: Salazar, Ulises Jesus Saldana
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The charged fermion masses of the three generations exhibit the two strong hierarchies m_3 >> m_2 >> m_1. We assume that also neutrino masses satisfy m_{nu 3} > m_{nu 2} > m_{nu 1} and derive the consequences of the hierarchical spectra on the fermionic mixing patterns. The quark and lepton mixing matrices are built in a general framework with their matrix elements expressed in terms of the four fermion mass ratios m_u/m_c, m_c/m_t, m_d/m_s, and m_s/m_b and m_e/m_mu, m_mu/m_tau, m_{nu 1}/m_{nu 2}, and m_{nu 2}/m_{nu 3}, for the quark and lepton sector, respectively. In this framework, we show that the resulting mixing matrices are consistent with data for both quarks and leptons, despite the large leptonic mixing angles. The minimal assumption we take is the one of hierarchical masses and minimal flavour symmetry breaking that strongly follows from phenomenology. No special structure of the mass matrices has to be assumed that cannot be motivated by this minimal assumption. This analysis allows us to predict the neutrino mass spectrum and set the mass of the lightest neutrino well below 0.01 eV. The method also gives the 1 sigma allowed ranges for the leptonic mixing matrix elements. Contrary to the common expectation, leptonic mixing angles are found to be determined solely by the four leptonic mass ratios without any relation to symmetry considerations as commonly used in flavor model building. Still, our formulae can be used to build up a flavor model that predicts the observed hierarchies in the masses---the mixing follows then from the procedure which is developed in this work.
description: 28 pages, 3 figures, 4 tables; v2: references added, Appendix C added, additional clarification and explanations in Sec. 2; matches version accepted by Nucl. Phys. B
Gradient-dependent upper bound for the exchange-correlation energy and application to density functional theory
Creators: name: Constantin, L. A.
name: Fabiano, E.
name: Terentjevs, A.
name: Della Sala, F.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We propose a simple gradient-dependent bound for the exchange-correlation energy (sLL), based on the recent non-local bound derived by Lewin and Lieb. We show that sLL is equivalent to the original Lieb-Oxford bound in rapidly-varying density cases but it is tighter for slowly-varying density systems. To show the utility of the sLL bound we apply it to the construction of simple semilocal and non-local exchange and correlation functionals. In both cases improved results, with respect to the use of Lieb-Oxford bound, are obtained showing the power of the sLL bound.
description: 5 pages, 2 figures
Modeling and simulation of the lateral photovoltage scanning method
Creators: name: Farrell, Patricio
name: Kayser, Stefan
name: Rotundo, Nella
Publisher: name: Weierstrass Institute
Year: 2020
Subjects: subject: Lateral-photovoltage-scanning method (LPS)
subject: semiconductor simulation
subject: van Roosbroeck system
subject: finite volume simulation
subject: crystal growth
subject: 35Q81
subject: 35K57
subject: 65N08

description: The fast, cheap and nondestructive lateral photovoltage scanning (LPS) method detects inhomogeneities in semiconductors crystals. The goal of this paper is to model and simulate this technique for a given doping profile. Our model is based on the semiconductor device equations combined with a nonlinear boundary condition, modelling a volt meter. To validate our 2D and 3D finite volume simulations, we use theory developed by Tauc [21] to derive three analytical predictions which our simulation results corroborate, even for anisotropic 2D and 3D meshes. Our code runs about two orders of magnitudes faster than earlier implementations based on commercial software [15]. It also performs well for small doping concentrations which previously could not be simulated at all due to numerical instabilities. Our simulations provide experimentalists with reference laser powers for which meaningful voltages can still be measured. For higher laser power the screening effect does not allow this anymore.
Männerchöre für das 3. eidgenössische Sängerfest in Bern am 13. und 14. August 1848
Creators: name: Eidgenössisches Sängerfest 3. 1848 Bern
Publisher: name: [Verlag nicht ermittelbar]; Druck der Haller'schen Buchdruckerei
Year: 1848

description: [s.c.]
Rovnoscydmus
Creators: name: Jałoszyński, Paweł
name: Perkovsky, Evgeny
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Rovnoscydmus

description: ? Rovnoscydmus sp. specimen 10
(Figs 23, 165–166)
Material studied. Late Eocene of Europe, Rovno amber: sex unknown; inclusion in elongate, irregular pyramid of amber 24.5 mm long (Fig. 23), collection number K-15548 (SIZK).
This specimen is preserved in cloudy and turbid amber and most of the important characters are not visible under a light microscope. However, its body form seems similar to that of Rovnoscydmus, and measurements support this determination.
Only incomplete measurements can be used to characterize this inclusion: BL 0.98 mm; HL 0.18 mm; AnL 0.48 mm; PL 0.30 mm; EL 0.50 mm.
description: Published as part of Jałoszyński, Paweł & Perkovsky, Evgeny, 2016, Diversity of Scydmaeninae (Coleoptera: Staphylinidae) in Upper Eocene Rovno amber, pp. 1-85 in Zootaxa 4157 (1) on page 55, DOI: 10.11646/zootaxa.4157.1.1, http://zenodo.org/record/262413
Kontinuität in der gegenwärtigen Liturgie?
Creators: name: Thomassen, Jürgen
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 3 Nr. 6 (1974): Internationale katholische Zeitschrift Communio, Band 3, Heft 6
Avoiding Landfills: A look at alternatives to sending agricultural plastics to the landfill
Creators: name: Gove, John
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: As the world moves towards an environmental tipping point, every aspect of what we create must be looked at critically. What products we create must have a use and a plan for their
end of life destination. Landfills and pollutants will not be acceptable outcomes for most circumstances. In this project, I will report on alternatives to landfills that are being developed
for agricultural plastic mulches.
I will package and synthesize all of my reporting into a multimedia piece that explains what plastic mulches are and why we rely on them. In the process I will tell the stories of characters shifting the paradigm in farming with plastics. Photography and videography will
complement a long-form written piece to give the viewer a holistic view of a side of agriculture not commonly publicized. Providing the public with an awareness increases the chances of future
action.
Non-Minimal Two-Loop Inflation
Creators: name: Inagaki, Tomohiro
name: Nakanishi, Ryota
name: Odintsov, Sergei D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the chaotic inflationary model using the two-loop effective potential of a self-interacting scalar field theory in curved spacetime. We use the potential which contains a non-minimal scalar curvature coupling and a quartic scalar self-interaction. We analyze the Lyapunov stability of de Sitter solution and show the stability bound. Calculating the inflationary parameters, we systematically explore the spectral index $n_s$ and the tensor-to-scalar ratio $r$, with varying the four parameters, the scalar-curvature coupling $ξ_0$, the scalar quartic coupling $λ_0$, the renormalization scale $μ$ and the e-folding number $N$. It is found that the two-loop correction on $n_s$ is much larger than the leading-log correction, which has previously been studied. We show that the model is consistent with the observation by Planck with WMAP and a recent joint analysis of BICEP2.
description: 11pages, 7figures
Die Einheit vom Altem und Neuem Testament
Creators: name: Groß, Heinrich
name: Mußner, Franz
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 3 Nr. 6 (1974): Internationale katholische Zeitschrift Communio, Band 3, Heft 6
303. Treating autoantibody mediated vasculitis with the IgG degrading enzyme imlifidase
Creators: name: Mårten Segelmark1,2,3
Publisher: name: Zenodo
Year: 2022
Subjects: Vasculitis
ANCA
Abstracts
Giant Cell Arthritis
MPA
GPA
EGPA
Takayasu
IgA vasculitis

description: Background: Autoantibodies directed to the non-collagenous domain of the alpha 3 chain of Type IV collagen cause small vessel vasculitis affecting capillaries of the kidneys and lungs. With standard treatment chances are slim to salvage renal function if treatment is started late. Imlifidase is the non-proprietary name for the immunoglobulin degrading enzyme of streptococcus pyogenous (IdeS) that in vivo can cleave all IgG antibodies both circulating and bound to basement membranes. Method: We conducted a multi-center (17 sites in five countries) phase 2a open-label study (EuaCT: 2016-004082-39) in 15 adults with anti-GBM antibodies and an eGFR <15 ml/min/1.73m2. All subjects received a single dose of 0.25 mg/kg of imlifidase on top of standard treatment, but with plasma-exchange only if autoantibodies rebounded. The primary outcome measure was safety and dialysis independency at 6 months. Results: At inclusion 10 patients were dialysis dependent and 5 had eGFR levels between 7-14 ml/min/1.73m2. Median age was 61 years (range 19-77), six were women. All kidney biopsies (available from 14) showed crescentic glomerulonephritis with few normal glomeruli (median 9.5%; range 0-35). Six hours after imlifidase infusion, all patients were negative in ELISA for anti-GBM antibodies. There were eight serious adverse events (including one death) reported, but none was assessed as probably or possibly related to the study ug. At six months 10 patients (67%) were dialysis independent, which is significantly higher as compared to 18% in a historical control cohort (p<0.001). Conclusion: Imlifidase (IdeS) rapidly degraded the autoantibodies in this study, and this was associated with renal recovery in most patients. There was no worrisome safety signal. These promising results encourage further development of this treatment option in this and other conditions where IgG autoantibodies constitute a threat against vital organ function. Disclosure: Mårten Segelmark has received research funds and consultancy fees and research funding from Hansa Pharma.
Measurement incompatibility and Schrödinger-EPR steering in a class of probabilistic theories
Creators: name: Banik, Manik
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Steering is one of the most counter intuitive non classical features of bipartite quantum system, first noticed by Schrödinger at the early days of quantum theory. On the other hand measurement incompatibility is another non classical feature of quantum theory, initially pointed out by N. Bohr. Recently the authors of Refs. [\href{http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.113.160402}{Phys. Rev. Lett. {\bf 113}, 160402 (2014)}] and [\href{http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.113.160403}{Phys. Rev. Lett. {\bf 113}, 160403 (2014)}] have investigated the relation between these two distinct non classical features. They have shown that a set of measurements is not jointly measurable (i.e. incompatible) if and only if they can be used for demonstrating Schrödinger-Einstein-Podolsky-Rosen steering. The concept of steering has been generalized for more general abstract tensor product theories rather than just Hilbert space quantum mechanics. In this article we discuss that the notion of measurement incompatibility can be extended for general probability theories. Further we show that the connection between steering and measurement incompatibility holds in a border class of tensor product theories rather than just quantum theory.
description: Accepted in Journal of Mathematical Physics (close to accepted version). arXiv admin note: text overlap with arXiv:1402.6562, arXiv:1406.6976, arXiv:1311.1462, arXiv:0707.0620 by other authors
304. A randomised, double-blind, controlled, study of rituximab and belimumab combination in AAV (COMBIVAS): study protocol.
Creators: name: McClure1, Mark
Publisher: name: Zenodo
Year: 2022
Subjects: Vasculitis
ANCA
Abstracts
Giant Cell Arthritis
MPA
GPA
EGPA
Takayasu
IgA vasculitis

description: Background: Dual B-cell targeted immunotherapy with B cell depletion (rituximab) and BAFF antagonism (belimumab) may enhance B cell targeting in ANCA-associated vasculitis (AAV) through several mechanis (1). Study Design: COMBIVAS is a randomized, double blind, placebo-controlled trial designed to evaluate the mechanistic effect of belimumab combined with rituximab in patients with active proteinase 3 (PR3)-AAV. Participants will be randomized 1:1 to receive rituximab plus prednisolone combined with belimumab (combination arm) or placebo (control arm). 30 participants will be evaluated in a per-protocol analysis. Trial duration is two years (12-months treatment, 12- months’ follow-up). Participants: Participants were recruited from 7 UK sites. Eligibility included age>18 years, severe active AAV (newly diagnosed or relapsing), and positive PR3 ANCA. Interventions: Belimumab (200mg) or belimumab placebo was administered subcutaneously on Day 1 and then weekly through to Week 51. Intravenous rituximab 1000mg was administered on Day 8 and Day 22 only. All participants started prednisolone 20 mg/day on Day 1 and followed a tapering regimen aiming for withawal by 3 months. Outcomes: Primary Outcome: Time to PR3-ANCA negativity; Key Secondary Outcomes: change from baseline in naïve, transitional, memory, activated, plasmablast and plasma cell subsets (B cell flow cytometry) in blood at Months 3, 12, and 24; time to clinical remission; time to relapse, incidence of serious adverse events. Exploratory biomarker assessments - Blood and urine were taken at multiple time points, with key analyses at 3 months (maximal B cell depletion), 12 months (end of treatment), 24 months (B cell reconstitution, end of follow-up). Inguinal lymph node and nasal mucosal biopsies were performed on a subgroup of participants before and three months after initiating treatment for the purpose of exploratory analyses (including single cell RNA sequencing) examining the mechanistic effects of combination B cell depletion within tissues. Discussion: This experimental medicine study provides a unique opportunity to gain detailed insights into the immunological mechanis of rituximab-belimumab combination therapy across multiple body compartments in the setting of AAV. Trial status - EUACT number: 2017-004645-24; Recruitment completed March 2021. Final study report due 2024. Disclosures: Rachel Jones has received grants/consultancy fees from GlaxoSmithKline, Vifor Pharma, ChemoCentryx and Roche. David Jayne’s disclosures of commercial conflicts for companies with marketed products for 2021 are: Astra-Zeneca, Aurinia, B, Boehringer-Ingelheim, GSK, Janssen, Novartis, Roche/Genentech, Takeda & Vifor.