cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2: of Efficacy of pre-operative quadriceps strength training on knee-extensor strength before and shortly following total knee arthroplasty: protocol for a randomized, dose-response trial (The QUADX-1 trial)
Creators: name: Husted, Rasmus
name: Troelsen, Anders
name: Thorborg, Kristian
name: Rathleff, Michael
name: Husted, Henrik
name: Bandholm, Thomas
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Computational Biology

description: TIDieR Checklist. (DOCX 31Â kb)
Additional file 5 of Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ-mediated pre-initiation complex
Creators: name: Li, Zhiran
name: Wu, Yunhao
name: Fu, Yangbo
name: Chen, Xia
name: Zhao, Xi
name: Wu, Xiaolong
name: Lu, Yajuan
name: He, Hui
name: Shen, Cong
name: Zheng, Bo
name: Yu, Jun
name: Sun, Fei
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 5. Primer sequences for qRT-PCR.
Additional file 1 of Prospective telehealth analysis of functional performance, frailty, quality of life, and mental health after COVID-19 hospitalization
Creators: name: Capin, Jacob J.
name: Wilson, Melissa P.
name: Hare, Kristine
name: Vempati, Swati
name: Little, Carley E.
name: McGregor, Donna
name: Castillo-Mancilla, Jose
name: Stevens-Lapsley, Jennifer E.
name: Jolley, Sarah E.
name: Erlandson, Kristine M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Appendix 1. Patient characteristics stratified by categorical age. Appendix 2. Demographics stratified by sex. Appendix 3. Demographics stratified by race/ethnicity groups. Appendix 4. Counts of surveys and calls completed by weeks post-hospitalization and categorical age.
Determinants of Soil Conservation Technologies Among Small-Scale Farmers in Tanzania; Evidence from National Panel Survey
Creators: name: Lasway, Jovin Aveline
name: Temba, George Raphael
name: Ruhinduka, Remidius Denis
name: Lasway, Jovin Aveline
name: Temba, George Raphael
name: Ruhinduka, Remidius Denis
Publisher: name: Unknown
Year: 2020
Subjects: subject: Environmental Economics and Policy
subject: Adoption of SCTs
subject: Soil erosion
subject: Panel data
subject: Binary probit model and Tanzania

description: The adoption of Soil Conservation Technologies (SCTs) in Tanzania is very low compared to other countries in Africa with related situation. Interventions were taken by introducing soil conservation practices. However, the adoption of these practices is far below the expectation. The objective of this study was to examine the determinants ofSCTs among maize small-scale farmers in Tanzania. Secondary data from the National Panel Survey was used in this study. A binary probit regression model was employed to analyse the data. The analysis results showed that access to extension services and training as well as plot value were positively correlated at significantly level with the adoption of the introduced soil and water conservation practices. On the other hand, soil steepness influenced the adoption of soil conservation practices negatively. The finding depicts that the identified physical, socioeconomic, and institutional factors influence the adoption of SCTs so; concerned bodies should consider these influential factors to enhance farmers’ adoption of soil conservation practices and promote agricultural productivity and environmental quality.
$CPT$-symmetric coupler with intermodal dispersion
Creators: name: Zezyulin, Dmitry A.
name: Kartashov, Yaroslav V.
name: Konotop, Vladimir V.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: A dual-core waveguide with balanced gain and loss in different arms and with intermodal coupling is considered. The system is not invariant under the conventional $PT$ symmetry but obeys $CPT$ symmetry where an additional spatial inversion $C$ corresponds to swapping the coupler arms. We show that second-order dispersion of coupling allows for unbroken $CPT$ symmetry and supports propagation of stable vector solitons along the coupler. Small-amplitude solitons are found in explicit form. The combined effect of gain-and-loss and dispersive coupling results in several interesting features which include a separation between the components in different arms, nontrivial dependence of stability of a soliton on its velocity, and the existence of more complex stationary two-hump solutions. Unusual decay dynamics of unstable solitons is discussed too.
description: to appear in Optics Letters
Can simple transmission chains foster collective intelligence in binary-choice tasks?
Creators: name: Moussaid, Mehdi
name: Yahosseini, Kyanoush Seyed
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: In many social systems, groups of individuals can find remarkably efficient solutions to complex cognitive problems, sometimes even outperforming a single expert. The success of the group, however, crucially depends on how the judgments of the group members are aggregated to produce the collective answer. A large variety of such aggregation methods have been described in the literature, such as averaging the independent judgments, relying on the majority or setting up a group discussion. In the present work, we introduce a novel approach for aggregating judgments - the transmission chain - which has not yet been consistently evaluated in the context of collective intelligence. In a transmission chain, all group members have access to a unique collective solution and can improve it sequentially. Over repeated improvements, the collective solution that emerges reflects the judgments of every group members. We address the question of whether such a transmission chain can foster collective intelligence for binary-choice problems. In a series of numerical simulations, we explore the impact of various factors on the performance of the transmission chain, such as the group size, the model parameters, and the structure of the population. The performance of this method is compared to those of the majority rule and the confidence-weighted majority. Finally, we rely on two existing datasets of individuals performing a series of binary decisions to evaluate the expected performances of the three methods empirically. We find that the parameter space where the transmission chain has the best performance rarely appears in real datasets. We conclude that the transmission chain is best suited for other types of problems, such as those that have cumulative properties.
title: Balsamaire (Inv. 2003.7.6941.4)
Creators: name: Paris, Pascal
name: Chevrier, Sébastien
name: Tisserand, Nicolas
Publisher: name: Conservatoire National des Données 3D (CND3D)
Year: 2024
Subjects: subject: balsamaire
subject: Artefact
subject: ACQUISITION

description: Modèle 3D
Large Thermoelectric Power Factor at Low Temperatures in One-Dimensional Telluride Ta4SiTe4
Creators: name: Inohara, Takumi
name: Okamoto, Yoshihiko
name: Yamakawa, Youichi
name: Yamakage, Ai
name: Takenaka, Koshi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report the discovery of a very large thermoelectric power over -400 microV K-1 in the whisker crystals of a one-dimensional telluride Ta4SiTe4, while maintaining a low electrical resistivity of rho = 2 mohm cm, yielding a very large power factor of P = 80 microW cm-1 K-2 at an optimum temperature of 130 K. This temperature is widely controlled from the cryogenic temperature of 50 K to room temperature by chemical doping, resulting in the largest P of 170 microW cm-1 K-2 at 220-280 K. These P values far exceed those of the Bi2Te3-Sb2Te3 alloys at around room temperature, offering an avenue for realizing the practical-level thermoelectric cooling at low temperatures. The coexistence of a one-dimensional electronic structure and a very small band gap appearing in the vicinity of the Dirac semimetals probably causes the very large power factors in Ta4SiTe4, indicating that the "one-dimensional Dirac semimetal" is a promising way to find high-performance thermoelectric materials for the low temperature applications.
description: 5 pages, 3 figures
GPDs at non-zero skewness in ADS/QCD model
Creators: name: Rinaldi, Matteo
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study Generalized Parton Distribution functions (GPDs) usually measured in hard exclusive processes and encoding information on the three dimensional partonic structure of hadrons and their spin decomposition, for non zero skewness within the AdS/QCD formalism. To this aim the canonical scheme to calculate GPDs at zero skewness has been properly generalized. Furthermore, we show that the latter quantities, in this non forward regime, are sensitive to non trivial details of the hadronic light front wave function, such as a kind of parton correlations usually not accessible in studies of form factors and GPDs at zero skewness.
description: 6 pages, 7 figures
Classifiers for centrality determination in proton-nucleus and nucleus-nucleus collisions
Creators: name: Altsybeev, Igor
name: Kovalenko, Vladimir
Publisher: name: arXiv
Year: 2016
Subjects: subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: Nuclear Experiment (nucl-ex)
subject: Machine Learning (stat.ML)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Centrality, as a geometrical property of the collision, is crucial for the physical interpretation of nucleus-nucleus and proton-nucleus experimental data. However, it cannot be directly accessed in event-by-event data analysis. Common methods for centrality estimation in A-A and p-A collisions usually rely on a single detector (either on the signal in zero-degree calorimeters or on the multiplicity in some semi-central rapidity range). In the present work, we made an attempt to develop an approach for centrality determination that is based on machine-learning techniques and utilizes information from several detector subsystems simultaneously. Different event classifiers are suggested and evaluated for their selectivity power in terms of the number of nucleons-participants and the impact parameter of the collision. Finer centrality resolution may allow to reduce impact from so-called volume fluctuations on physical observables being studied in heavy-ion experiments like ALICE at the LHC and fixed target experiment NA61/SHINE on SPS.
description: To be published in proceedings of the "XIIth Quark Confinement and the Hadron Spectrum" conference (Thessaloniki, 2016)
Modeling of radio emission from a particle cascade in a magnetic field and its experimental validation
Creators: name: Zilles, Anne
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The SLAC T-510 experiment was designed to compare controlled laboratory measurements of radio emission of particle showers to predictions using particle-level simulations, which are relied upon in ultra-high-energy cosmic-ray air shower detection. Established formalisms for the simulation of radio emission physics, the "endpoint" formalism and the "ZHS" formalism, lead to results which can be explained by a superposition of magnetically induced transverse current radiation and charge-excess radiation due to the Askaryan effect. Here, we present the results of Geant4 simulations for the SLAC T-510 experiment, taking into account the details of the experimental setup (beam energy, target geometry and material, magnetic field configuration, and refraction effects) and their comparison to measured data with respect to e.g. signal polarisation, linearity with magnetic field, and angular distribution. We find that the microscopic calculations reproduce the measurements within uncertainties and describe the data well.
description: To be published in the Proceedings of the ARENA2016 conference, Groningen, The Netherlands
Additional file 2 of Prospective telehealth analysis of functional performance, frailty, quality of life, and mental health after COVID-19 hospitalization
Creators: name: Capin, Jacob J.
name: Wilson, Melissa P.
name: Hare, Kristine
name: Vempati, Swati
name: Little, Carley E.
name: McGregor, Donna
name: Castillo-Mancilla, Jose
name: Stevens-Lapsley, Jennifer E.
name: Jolley, Sarah E.
name: Erlandson, Kristine M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2: Supplemental Figure 1. The flow chart depicts how many individuals were contacted and reasons why individuals did not enroll or participate in the study.
Datenmanagement planen mit SaxFDM-RDMO (Einführung)
Creators: name: Voigt, Pia
Publisher: name: Zenodo
Year: 2024
Subjects: Forschungsdatenmanagement
FDM
Datenmanagementpläne
RDMO
DMP
RDM
SaxFDM

description: Dieser Foliensatz führt Sie in die Benutzung und die Funktionalitäten von SaxFDM-RDMO ein. Sollten Sie weitere Fragen zur Benutzung der Software haben, wenden Sie sich gern an das SaxFDM-Team: kontakt@saxfdm.de.

Die Folien wurden im Rahmen des Fokusprojekts "SaxFDM DMP 2" erstellt, gefördert durch das Sächsische Staatsministerium für Wissenschaft, Kultur und Tourismus.
Time-Resolved and Temperature Tuneable Measurements of Fluorescent Intensity using a Smartphone Fluorimeter
Creators: name: Hossain, Md Arafat
name: Canning, John
name: Yu, Zhikang
name: Ast, Sandra
name: Rutledge, Peter J.
name: Wong, Joseph K. H.
name: Jamalipour, Abbas
name: Crossley, Maxwell J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics Education (physics.ed-ph)
subject: Chemical Physics (physics.chem-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: A smartphone fluorimeter capable of time-based fluorescence intensity measurements at various temperatures is reported. Excitation is provided by an integrated UV LED (370 nm) and detection obtained using the in-built CMOS camera. A Peltier is integrated to allow measurements of the intensity over T = 10 to 40 C with a maximum temperature resolution of DELTA T ~ 0.1 C. All components are controlled using a smartphone battery powered Arduino microcontroller and a customised Android application that allows sequential fluorescence imaging and quantification every DELTA t = 4 seconds. The temperature dependence of fluorescence intensity for four emitters (Rhodamine B, Rhodamine 6G, 5,10,15,20-tetraphenylporphyrin and 6-(1,4,8,11-tetraazacyclotetradecane)2-ethyl-naphthalimide) are characterised. The normalised fluorescence intensity over time of the latter chemosensor dye complex in the presence of Zn ion is observed to accelerate with an increasing rate constant, k = 1.94 min-1 at T = 15 C and k = 3.64 min-1 at T = 30 C, approaching a factor of ~ 2 with only a change in temperature of DELTA T = 15 C. Thermally tuning these twist and bend associated rates to optimise sensor approaches and device applications is proposed.
description: The manuscript was submitted to Chemical Science - 04 Nov 2016; authors informed it was unsuitable for that journal 24 Feb 2017. Temperature and time tuning was publicly disclosed at APOS, Shanghai China 9 Jun 2017 in invited talk Canning et al. Temperature tuning also in APOS student presentation Hossain et al
Economic Expansion and Environmental Degradation in Ghana: A Sector Decomposition Analysis
Creators: name: Aboagye, Solomon
name: Appiah-Konadu, Paul
name: Acheampong, Vera
name: Aboagye, Solomon
name: Appiah-Konadu, Paul
name: Acheampong, Vera
Publisher: name: Unknown
Year: 2020
Subjects: subject: Environmental Economics and Policy
subject: Economic Expansion
subject: Environmental Degradation
subject: Environmental Kuznets Curve
subject: Autoregressive Distributive Lagged Models
subject: Ghana

description: Recent research has focused on exploring the relationship between economic expansion and environmental degradation, particularly in developing and emerging economies. This has become necessary given the several attempts by economies to increase productivity while safeguarding the environment to foster sustainable development. This study progresses from previous research to examine the disaggregated impact of economic expansion on the environment. Consequently, the study employs the Autoregressive Distributive Lagged (ARDL) approach to cointegration and annual time series data from 1985 to 2015, from the World Bank database, to examine the disaggregated impact of economic expansion on the environment in Ghana. The study finds that initial stages of agricultural expansion tends to deteriorate the environment, but as agricultural productivity increases beyond a certain point, although the effect on BOD and deforestation may still rise, CO2 emission reduces. More so, expansion in industry results in a rise in all three indicators of environmental degradation, both in the short and long run while a harmful effect was found between expansion in service output and CO2 emission at the initial stages of productivity, but not in the long-run. The impact on BOD and deforestation is harmful with expansion in service output. The results point to the fact that expansions in agriculture and services will eventually result in the reduction of CO2 emissions beyond some productivity threshold.
21 cm Angular Power Spectrum from Minihalos as a Probe of Primordial Spectral Runnings
Creators: name: Sekiguchi, Toyokazu
name: Takahashi, Tomo
name: Tashiro, Hiroyuki
name: Yokoyama, Shuichiro
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Measurements of 21 cm line fluctuations from minihalos have been discussed as a powerful probe of a wide range of cosmological models. However, previous studies have taken into account only the pixel variance, where contributions from different scales are integrated. In order to sort out information from different scales, we formulate the angular power spectrum of 21 cm line fluctuations from minihalos at different redshifts, which can enhance the constraining power enormously. By adopting this formalism, we investigate expected constraints on parameters characterizing the primordial power spectrum, particularly focusing on the spectral index $n_s$ and its runnings $α_s$ and $β_s$. We show that future observations of 21 cm line fluctuations from minihalos, in combination with cosmic microwave background, can potentially probe these runnings as $α_s \sim {\cal O}(10^{-3})$ and $β_s \sim {\cal O}(10^{-4})$. Its implications to the test of inflationary models are also discussed.
description: 26 pages, 7 figures, 6 tables
A pH-responsive complex based on supramolecular organic framework for drug-resistant breast cancer therapy
Creators: name: Zhang, Yun-Chang
name: Zeng, Pei-Yu
name: Ma, Zhi-Qiang
name: Xu, Zi-Yue
name: Wang, Ze-Kun
name: Guo, Beibei
name: Yang, Feng
name: Li, Zhan-Ting
Publisher: name: Taylor & Francis
Year: 2021
Subjects: Space Science
Medicine
Pharmacology
Biotechnology
Cancer
Hematology

description: Chemotherapy is one of the main ways to treat breast cancer clinically. However, the multidrug resistance to anti-tumor drugs limits their clinical use. To overcome these drawbacks, development of drug delivery systems (DDSs) has attracted more and more attention in cancer therapy. At present, the preparation and purification process are complicated for many reported DDSs, while clinic calls for new DDSs that are more convenient for preparation. Here, a new pH-responsive supramolecular organic framework drug delivery complex loading doxorubicin (DOX) is fabricated. Anti-tumor activity of the system in vitro was investigated by cell cytotoxicity, uptake assay, and cell apoptosis analysis. The anti-tumor activity in vivo was investigated by inspecting nude mice body weight, tumor volume, and weight, also a preliminary mechanism probe was conducted by HE and TUNEL staining. The DOX@SOF displayed high stability, good biocompatibility, and pH regulated drug release. At acid condition, the hydrazone bonds would be broken, which result in the dissociation of SOF, and then the drugs would be released from the system. Furthermore, DOX@SOF enhanced cellular internalization. Both in vitro and in vivo experiments reflected that DOX@SOF could enhance the anti-tumor activity of DOX for the MCF-7/ADR tumor cells and tumors. This study provides a highly efficient strategy to prepare stimulus-responsive supramolecular drug delivery complex for treatment of drug-resistant cancer, the results presented inspiring scientific interests in exploring new drug delivery strategy and reversing multi-drug resistance for clinical chemotherapy.
Additional file 1: of Efficacy of pre-operative quadriceps strength training on knee-extensor strength before and shortly following total knee arthroplasty: protocol for a randomized, dose-response trial (The QUADX-1 trial)
Creators: name: Husted, Rasmus
name: Troelsen, Anders
name: Thorborg, Kristian
name: Rathleff, Michael
name: Husted, Henrik
name: Bandholm, Thomas
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Computational Biology

description: SPIRIT Checklist. (DOC 122Â kb)
Lettre de Laurent Bonnemant à Jean-François Séguier, 1783-08-25
Creators: name: Bonnemant, Laurent
name: Bonnemant, Laurent
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Antiquités (général)
Epigraphie

description: [transcription] [Bonnemant]

Monsieur,

Je ne saurais laisser partir de R.P. Dumont, religieux minime, sans lui donner une lettre qui me rappelle dans votre précieux souvenir et qui vous renouvelle les protestations du respectueux attachement que je vous ai voué. Pour ce savant religieux, vous le connaîtrez bientôt. S'il ne lui est pas possible de vous donner des lumières, du moins verrez-vous d'abord qu'il en est très abondamment pourvu. Il a vingt un an de séjour à Rome sur le corps, et certes il n'a pas perdu son temps. Le peu de temps qu'il m'a été loisible de jouir de lui m'a beaucoup instruit et je vous prie de lui recommander de me faire part de ses trésors. à son retour il doit venir passer encore quelques jours ici, après avoir vu vos antiquités. Je me propose de le questionner beaucoup. Je désire qu'il me donne des nouvelles de vous telles [que] le public, les lettres, vos amis et votre serviteur en particulier les demandent. Il s'est fait depuis peu une fouille près de notre ville. On y a trouvé des urnes, des lampes, & c. Voici deux nouvelles inscriptions. La première a été portée dans ma chambre, et je la garde. Là voici.

D.M.

SEX. DOMITII

BLASTI

IN FRONTEZ

P. XX

La seconde a été transportée à l'hôtel de ville:

ASIATICI

CONEVLEIORVM

O.H.S.S.

Reinesius vous donne l'explication de ces sigles.

Je suis, Monsieur, avec le plus respectueux attachement,

Votre très humble et

Obéissant serviteur

Bonnement prêtre

25 août 1783
description: [note autre main] [Bonnemant]
description: [personnes citées] Etienne Dumont
description: [reférence bibliographique citée] Reinesius, Thomas, Syntagma inscriptionum antiquarum cum primis Romae veteris quarum omissa est recensio in vasto Jani Gruteri opere..., Lipsiae, sumpt. J. Fritschii, 1682.
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 135_4, fol. 58
description: Source: ark:/12148/btv1b100151415
Do Reichenbachian Common Cause Systems of Arbitrary Finite Size Exist?
Creators: name: Mazzola, Claudio
name: Evans, Peter
Publisher: name: arXiv
Year: 2017
Subjects: subject: Other Statistics (stat.OT)
subject: Artificial Intelligence (cs.AI)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: The principle of common cause asserts that positive correlations between causally unrelated events ought to be explained through the action of some shared causal factors. Reichenbachian common cause systems are probabilistic structures aimed at accounting for cases where correlations of the aforesaid sort cannot be explained through the action of a single common cause. The existence of Reichenbachian common cause systems of arbitrary finite size for each pair of non-causally correlated events was allegedly demonstrated by Hofer-Szabó and Rédei in 2006. This paper shows that their proof is logically deficient, and we propose an improved proof.
Additional file 6 of Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ-mediated pre-initiation complex
Creators: name: Li, Zhiran
name: Wu, Yunhao
name: Fu, Yangbo
name: Chen, Xia
name: Zhao, Xi
name: Wu, Xiaolong
name: Lu, Yajuan
name: He, Hui
name: Shen, Cong
name: Zheng, Bo
name: Yu, Jun
name: Sun, Fei
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 6. Antibodies used in this study.
Falls and social isolation in older adults
Creators: name: Tricco, Andrea
name: Thomas, Sonia
name: Ramkissoon, Naveeta
name: Mitchell, Gary
name: Fortune, Jennifer
name: Watt, Jennifer
name: straus, sharon
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: clinical research
subject: older adults
subject: scoping review
subject: social isolation

description: A scoping review to summarize evidence on the relationship between falls and subsequent social isolation in older adults, specifically looking at risk factors, protective factors, and how the COVID-19 context affects this relationship.
Additional file 1 of Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway
Creators: name: Chen, Zong
name: Ding, Yong
name: Zeng, Ying
name: Zhang, Xue-Ping
name: Chen, Jian-Yan
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Additional file 1.
A tumor microenvironment-responsive micelle co-delivered radiosensitizer Dbait and doxorubicin for the collaborative chemo-radiotherapy of glioblastoma
Creators: name: Zhang, Shuyue
name: Jiao, Xiuxiu
name: Heger, Michal
name: Gao, Shen
name: He, Mei
name: Xu, Nan
name: Zhang, Jigang
name: Zhang, Mingjian
name: Yu, Yuan
name: Ding, Baoyue
name: Ding, Xueying
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Glioblastoma is rather recalcitrant to existing therapies and effective interventions are needed. Here we report a novel microenvironment-responsive micellar system (ch-K5(s-s)R8-An) for the co-delivery of the radiosensitizer Dbait and the chemotherapeutic doxorubicin (DOX) to glioblastoma. Accordingly, the ch-K5(s-s)R8-An/(Dbait-DOX) micelles plus radiotherapy (RT) treatment resulted in a high degree of apoptosis and DNA damage, which significantly reduced cell viability and proliferation capacity of U251 cells to 64.0% and 16.3%, respectively. The angiopep-2-modified micelles exhibited substantial accumulation in brain-localized U251 glioblastoma xenografts in mice compared to angiopep-2-lacking micelles. The ch-K5(s-s)R8-An/(Dbait-DOX) + RT treatment group exhibited the smallest tumor size and most profound tumor tissue injury in orthotopic U251 tumors, leading to an increase in median survival time of U251 tumor-bearing mice from 26 days to 56 days. The ch-K5(s-s)R8-An/(Dbait-DOX) micelles can be targeted to brain-localized U251 tumor xenografts and sensitize the tumor to chemotherapy and radiotherapy, thereby overcoming the inherent therapeutic challenges associated with malignant glioblastoma.
Intra-wire coupling in segmented Ni/Cu nanowires deposited by electrodeposition
Creators: name: Sergelius, Philip
name: Lee, Ji
name: Fruchart, Olivier
name: Salem, Mohamed
name: Allende, Sebastian
name: Escobar, Robert
name: Gooth, Johannes
name: Zierold, Robert
name: Toussaint, Jean-Christophe
name: Schneider, Sebastian
name: Pohl, Darius
name: Rellinghaus, Bernd
name: Martin, Sylvain
name: Garcia, Javier
name: Reith, Heiko
name: Spende, Anne
name: Toimil-Molares, Maria
name: Altbir, Dora
name: Cowburn, Russel
name: Görlitz, Detlef
name: Nielsch, Kornelius
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Segmented magnetic nanowires are a promising route for the development of three dimensional data storage techniques. Such devices require a control of the coercive field and the coupling mechanisms between individual magnetic elements. In our study, we investigate electrodeposited nanomagnets within host templates using vibrating sample magnetometry and observe a strong dependence between nanowire length and coercive field (25 nm to 5 $μ$m) and diameter (25 nm to 45 nm). A transition from a magnetization reversal through coherent rotation to domain wall propagation is observed at an aspect ratio of approximately 2. Our results are further reinforced via micromagnetic simulations and angle dependent hysteresis loops. The found behavior is exploited to create nanowires consisting of a fixed and a free segment in a spin-valve like structure. The wires are released from the membrane and electrically contacted, displaying a giant magnetoresistance effect that is attributed to individual switching of the coupled nanomagnets. We develop a simple analytical model to describe the observed switching phenomena and to predict stable and unstable regimes in coupled nanomagnets of certain geometries.
Assessing Uncertainties in X-ray Single-particle Three-dimensional reconstructions
Creators: name: Engblom, Stefan
name: Nettelblad, Carl
name: Liu, Jing
Publisher: name: arXiv
Year: 2017
Subjects: subject: Methodology (stat.ME)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA. These two-dimensional diffraction patterns can be practically reconstructed and retrieved down to a resolution of a few \angstrom. In principle, a sufficiently large collection of diffraction patterns will contain the required information for a full three-dimensional reconstruction of the biomolecule. The computational methodology for this reconstruction task is still under development and highly resolved reconstructions have not yet been produced. We analyze the Expansion-Maximization-Compression scheme, the current state of the art approach for this very challenging application, by isolating different sources of uncertainty. Through numerical experiments on synthetic data we evaluate their respective impact. We reach conclusions of relevance for handling actual experimental data, as well as pointing out certain improvements to the underlying estimation algorithm. We also introduce a practically applicable computational methodology in the form of bootstrap procedures for assessing reconstruction uncertainty in the real data case. We evaluate the sharpness of this approach and argue that this type of procedure will be critical in the near future when handling the increasing amount of data.
description: 21 pages
Infrastructure Growth, Household Vulnerability and Response to Shocks in Kenya
Creators: name: Musyoka, Philip K
name: Onjala, Joseph
name: Mureithi, Leopold P
name: Musyoka, Philip K
name: Onjala, Joseph
name: Mureithi, Leopold P
Publisher: name: Unknown
Year: 2020
Subjects: subject: Public Economics
subject: vulnerability
subject: shocks
subject: coping strategies
subject: infrastructure

description: Households in most rural areas of developing countries are likely to suffer shocks contributed by their livelihoods’ dependence on natural resources as well as due to their physical isolation from the mainstream economy Using pooled cross-sectional data from Kenya, this paper investigates the association between changes in physical infrastructure stocks and access levels on one hand, and household vulnerability to shocks as well as the response strategies to shocks as markets for risk sharing develop and transaction costs are reduced over time through physical infrastructure growth. Results reveal that between 2005/06 and 2015/16, there was a reduction in household vulnerability to the general shocks with the reduction being higher for urban households; rural households’ vulnerability to food shocks reduced more compared to urban households; and finally, both rural and urban households increased their use of infrastructure-supported ex-post coping strategies such as savings and borrowing to respond to food-security shocks, with the adoption being higher by five percentage points among rural households. The study finds a plausible association between physical infrastructure changes and household vulnerability and coping strategies to shocks. The findings imply the importance of developing physical infrastructure as a strategy for reducing vulnerability to livelihood shocks.
Additional file 2 of Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway
Creators: name: Chen, Zong
name: Ding, Yong
name: Zeng, Ying
name: Zhang, Xue-Ping
name: Chen, Jian-Yan
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Additional file 2.
MOESM3 of A 13-year real-life study on efficacy, safety and biological effects of Vespula venom immunotherapy
Creators: name: Albanesi, Marcello
name: Nico, Andrea
name: Sinisi, Alessandro
name: Giliberti, Lucia
name: Rossi, Maria
name: Rossini, Margherita
name: Kourtis, Georgios
name: Rucco, Anna
name: Loconte, Filomena
name: Muolo, Loredana
name: Zurlo, Marco
name: Bona, Danilo
name: Caiaffa, Maria
name: Macchia, Luigi
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 3: Table S3. DHS VIT protocol.
title: AN, Registre des écrous du Châtelet, Y5266, f. p1000842
Creators: name: Claustre, Julie
name: Nationales, Archives
name: Archives Nationales
name: Claustre, Julie
name: ArchivesNationales/J.CLAUSTRE/H.REGAZZI/2020
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Châtelet
subject: registre

description: Registre des écrous du Châtelet, Archives Nationales, Y5266. Numérisation en mode image.
description: Bibliographic citation: Archives Nationales, Registre des écrous du Châtelet, Y5266, f. p1000842
Design of hydroxy-α-sanshool loaded nanostructured lipid carriers as a potential local anesthetic
Creators: name: Tan, Fengming
name: Xu, Lulu
name: Liu, Yanling
name: Li, Huan
name: Zhang, Dahan
name: Qin, Cuiying
name: Han, Yang
name: Han, Jing
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified

description: Hydroxy-α-sanshool (HAS), extracted from Zanthoxylum piperitum, is commonly used in oral surgery to relief pain. However, the application of HAS is limited in clinical practice due to its poor stability. This study focuses on the design of a novel nano-formulation delivery system for HAS to improve its stability and local anesthetic effect. Hydroxy-α-sanshool loaded nanostructured lipid carriers (HAS-NLCs) were prepared by melting emulsification and ultra-sonication using monostearate (GMS) and oleic acid (OA) as lipid carriers, and poloxamer-188 (F68) as a stabilizer. Besides, the formulation was optimized by response surface methodology (RSM). Then, the best formulation was characterized for particle size, polydispersity index (PDI), zeta potential, entrapment efficiency (EE%), drug loading (DL%), differential scanning calorimetry (DSC), and morphology (transmission electron microscopy, TEM). The obtained HAS-NLCs were homogeneous, near spherical particles with high DL% capacity. The stability of HAS-NLCs against oxygen, light, and heat was greatly improved over 10.79 times, 3.25 times, and 2.09 times, respectively, compared to free HAS. In addition, HAS-NLCs could exhibit sustained release in 24 h following a double-phase kinetics model in vitro release study. Finally, HAS-NLCs had excellent anesthetic effect at low dose in formalin test compared with free HAS and lidocaine, which indicated HAS-NLCs were a potential local anesthesia formulation in practice.
Computational Efficiency and Amdahl's law for the Adaptive Resolution Simulation Technique
Creators: name: Junghans, Christoph
name: Agarwal, Animesh
name: Site, Luigi Delle
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: We discuss the computational performance of the adaptive resolution technique in molecular simulation when it is compared with equivalent full coarse-grained and full atomistic simulations. We show that an estimate of its efficiency, within $10-15\%$ accuracy, is given by the Amdahl's Law adapted to the specific quantities involved in the problem. The derivation of the predictive formula is general enough that it may be applied to the general case of molecular dynamics approaches where a reduction of degrees of freedom in a multiscale fashion occurs.
Phenylboronic ester-modified polymeric nanoparticles for promoting TRP2 peptide antigen delivery in cancer immunotherapy
Creators: name: Wang, Qiyan
name: Dong, Zhipeng
name: Lou, Fangning
name: Yin, Yunxue
name: Zhang, Jiahao
name: Wen, Hanning
name: Lu, Tao
name: Wang, Yue
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: The tremendous development of peptide-based cancer vaccine has attracted incremental interest as a powerful approach in cancer management, prevention and treatment. As successful as tumor vaccine has been, major challenges associated with achieving efficient immune response against cancer are (1) drainage to and retention in lymph nodes; (2) uptake by dendritic cells (DCs); (3) activation of DCs. In order to overcome these barriers, here we construct PBE-modified TRP2 nanovaccine, which comprises TRP2 peptide tumor antigen and diblock copolymer PEG-b-PAsp grafted with phenylboronic ester (PBE). We confirmed that this TRP2 nanovaccine can be effectively trapped into lymph node, uptake by dendritic cells and induce DC maturation, relying on increased negative charge, ROS response and pH response. Consistently, this vehicle loaded with TRP2 peptide could boost the strongest T cell immune response against melanoma in vivo and potentiate antitumor efficacy both in tumor prevention and tumor treatment without any exogenous adjuvant. Furthermore, the TRP2 nanovaccine can suppress the tumor growth and prolong animal survival time, which may result from its synergistic effect of inhibiting tumor immunosuppression and increasing cytotoxic lymphocyte (CTL) response. Hence this type of PBE-modified nanovaccine would be widely used as a simple, safe and robust platform to deliver other antigen in cancer immunotherapy.
Environmental Data Science book: a computational notebook community for open environmental science
Creators: name: Coca-Castro, Alejandro
Publisher: name: Zenodo
Year: 2023

description: During this talk, Alejandro described the EDS book project (www.edsbook.org) focused on how to contribute, infrastructure, achievements, priorities and lessons learned from the 2023 Climate Informatics Reproducibility Challenge.

Presented at Session 7: Impacts of Climate Change, a UK statistical and data science perspective of 2023 TIES Regional Meeting on 2023-07-25.
Additional file 1: of Health-related quality of life among healthy elderly Iranians: a systematic review and meta-analysis of the literature
Creators: name: Sogand Tourani
name: Behzadifar, Masoud
name: Martini, Mariano
name: Aidin Aryankhesal
name: Mirghaed, Masood Taheri
name: Salemi, Morteza
name: Meysam Behzadifar
name: Bragazzi, Nicola
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Pooled scores of each health-related quality of life domain/sub-scale assessed with the Short-Form 36 questionnaire. (DOCX 99Â kb)
A "hidden" transition in heavy fermion compound CeB$_{6}$ at $T\sim$ 20 K?
Creators: name: Lu, Haiyan
name: Huang, Li
Publisher: name: arXiv
Year: 2016
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The temperature-dependent electronic structures of heavy fermion compound CeB$_{6}$ are investigated thoroughly by means of the combination of density functional theory and single-site dynamical mean-field theory. The band structure, density of states, and 4$f$ valence state fluctuation of CeB$_{6}$ are calculated in a broad temperature range of 10 $\sim$ 120 K. Overall, the 4$f$ electrons remain incoherent, approximately irrespective of the temperature. However, we find that these observables exhibit some unusual features near 20 K. In addition, the evolution of 4$f$ orbital occupancy, total angular momentum, and total energy with respect to temperature shows apparent singularity around 20 K. We believe that these tantalizing characteristics are probably related to a "hidden" electronic transition.
description: 7 pages, 6 figures
Valuations of $p$-adic regulators of cyclic cubic fields
Creators: name: Hofmann, Tommy
name: Zhang, Yinan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11Y40, 11R16 (Primary), 11K41, 11R27 (Secondary)

description: We compute the $p$-adic regulator of cyclic cubic extensions of $\mathbb Q$ with discriminant up to $10^{16}$ for $3
Additional file 3 of Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway
Creators: name: Chen, Zong
name: Ding, Yong
name: Zeng, Ying
name: Zhang, Xue-Ping
name: Chen, Jian-Yan
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Additional file 3.
Additional file 2: of Cost-effectiveness of prostate cancer screening: a systematic review of decision-analytical models
Creators: name: Sanghera, Sabina
name: Coast, Joanna
name: Martin, Richard
name: Donovan, Jenny
name: Mohiuddin, Syed
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Term used for conservative management. A summary table of the terms and definitions of conservative management used (DOCX 12Â kb)
Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy
Creators: name: He, Peng
name: Xu, Shenglin
name: Guo, Zehao
name: Yuan, Peng
name: Liu, Yulei
name: Chen, Yu
name: Zhang, Tiantian
name: Que, Yukang
name: Hu, Yong
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: The traditional systemic chemotherapy through intravenous infusion of doxorubicin (DOX) has many side effects. The aim of this study was to develop a PLGA-based DOX-loaded implant and to evaluate the efficacy and drug metabolism distribution of the implant in intratumoral chemotherapy for osteosarcoma (OS). In this study, implants containing DOX, poly(d,l-lactide-co-glycolide), and polyethylene glycol 4000 were prepared by melt-molding method. Then, the antitumor activity and systemic drug distribution of the implants were tested in a K7M2 OS bearing mouse model. The scanning electron microscope images showed that DOX was uniformly dispersed in the polymer matrix. Both the in vitro and in vivo release profiles of implants are characterized by three-phase release. Implantation of DOX-loaded implants into tumors can inhibit tumor growth in a dose-dependent manner. The pharmacokinetic behavior shows that intratumor chemotherapy through implants has a much higher drug concentration in tumors than in normal tissues, which may be the reason for improving antitumor activity and reducing systemic side effects. In summary, the drug release of the implants prepared in this study is sustained and stable, which promotes long-term local accumulation of drugs in tumors, improves the efficacy of chemotherapy and has low toxicity to normal tissues.
On the digital representation of smooth numbers
Creators: name: Bugeaud, Yann
name: Kaneko, Hajime
Publisher: name: arXiv
Year: 2017
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11A63, 11J86

description: Let $b \ge 2$ be an integer. Among other results, we establish, in a quantitative form, that any sufficiently large integer which is not a multiple of $b$ cannot have simultaneously only few distinct prime factors and only few nonzero digits in its representation in base $b$.
description: 10 pages