cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Evaluation of the Impact of Controlled Tile Drainage on Surface Water Quality in the South Nation River Watershed
Creators: name: Que, Zhenyang
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011

description: In Ontario, many agriculture-dominated watersheds like The South Nation River watershed are experiencing ecosystem deterioration mainly resulting from agricultural activities. A promising best management practice, controlled tile drainage (CTD), maintains water and nutrients through controllable facilities and releases them in an intermittent manner, when available storage in the drains is exceeded. This thesis is to evaluate how much water quality improvement can be expected if CTD adopted at watershed scale on the basis of experimental data from the WEBs project. A watershed model AnnAGNPS was applied, calibrated and validated on the watershed. Simulation results indicate that CTD can significantly improve surface water quality by reducing nitrogen losses from agricultural areas. This research creatively uses the AnnAGNPS model to simulate CTD, and it also provides a reliable link the model to observations from experimental CTD fields. So far, there is no related research found from the literature.
La Gouvernance Confucéenne : moralité, orthopraxie et expressions identitaires
Creators: name: Payette, Alex
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Renouveau du Confucianisme
Confucianisme Local
Gouvernance culturelle
Confucianisme religieux

description: Depuis la fondation de la République populaire de Chine, le confucianisme fut mis de côté par le Parti communiste chinois. À partir de la fin des années 1980, on décèle un regain d’intérêt pour celui-ci autant dans la sphère intellectuelle que politique. À la suite de plusieurs recherches et de débats concernant la religiosité et la politisation du confucianisme, nous avons premièrement essayé de savoir comment se traduisent empiriquement ces derniers. De façon plus spécifique, nous avons cherché à comprendre l’importance politique des groupes confucéens. Nous nous sommes tournés du côté de la gouvernance et avons tenté de voir de quelles façons ces derniers y participent, ou encore veulent y prendre part. L’idée principale étayée dans cette thèse est de dire que les groupes confucéens participent activement à la gouvernance par l’intermédiaire de leurs enseignements et de leurs activités qui sont enchâssées dans le discours étatique en matière d’harmonie sociale. Ce faisant, ils prennent par à la mise en place de l’orthodoxie et de l’orthopraxie confucéenne du Parti. Par le biais de l’approche théorique que représentent les stratégies de développement culturel – gouvernance culturelle, nous avons identifié deux types de groupes confucéens en Chine, soit les groupes « ascendants » et « descendants ». Tous deux participent à la mise en place de l’orthodoxie et de l’orthopraxie confucéenne du Parti chacun à leur manière. Afin d’étayer notre argument, nous avons étudié cinq sites qui ne sont pas mobilisés par la littérature existante. À l’aide d’entretiens et d’observations directes, nous avons pu découvrir que, malgré leurs différences respectives, ces deux types de groupes prennent, ou encore veulent prendre part à la gouvernance de façons similaires. Les premiers forment une expression identitaire qui parfois s’affirme en dehors des frontières étatiques et offre une religiosité confucéenne ambiguë. Les groupes « descendants » structurent le champ confucéen et de surcroît, encadrent la façon dont il peut être étudié et comment il doit se pratiquer. Ceci dit, tous deux participent à la diffusion du message étatique en matière de confucianisme et d’harmonie sociale.
The Development of a Workplace-Based Surgical Clinic Assessment Tool
Creators: name: Rekman, Janelle
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Surgery
Resident
Surgical Residency Education
Assessment
Clinic
Tool
Competence
Competency Based Medical Education

description: Purpose of Study: Workplace-based assessment is an opportunity for a learner to be assessed in their community of practice by an expert rater. The challenges and biases brought into this assessment relationship are complex. A shift towards Competency Based Medical Education in post-graduate residency education has triggered consideration of how to implement feasible assessment tools for the operating room, the in-patient ward, and the outpatient clinic. Competent performance in outpatient clinic is vital to surgical practice, yet no assessment tool currently exists to assess daily performance of technical and nontechnical skills of surgery residents. This project describes the development of a competency-based assessment tool, the Ottawa Clinic Assessment Tool (OCAT). Research Question: How does the OCAT demonstrate validity for measurement of surgical resident performance in clinic? Method: A consensus group of experts was gathered to generate ideas reflective of a competent ‘generalist’ surgeon in clinic. An entrustability anchor scale was developed. A six-month pilot study of the OCAT was conducted in orthopedics, general surgery and obstetrics and gynecology with quantitative and qualitative evidence of validity collected. Two subsequent feedback sessions, and a survey for staff and residents evaluated the OCAT for clarity and utility. Results: The OCAT was developed as a 13-item tool, with a global assessment item and 2 short answers questions. 44 staff surgeons completed 132 OCAT assessments of 79 residents. Psychometric data was collected as evidence of internal structure validity and relations with other variables. Analysis of feedback indicated the rating scale was practical and useful for surgeons and residents. Conclusions & Contribution to the Research Field: Surgical programs will require a daily clinic assessment tool to help define resident competency progression. Multiple sources of validity evidence collected in this pilot project demonstrate that the OCAT can measure resident clinic competency in a valid and feasible manner.
title: Kontrol'nye spiski dlja izucenija i ocenki sostojanija promyslennych ob'ektov s opasnymi dlja vody vescestvami i preparatami v celljulozno-bumaznoj promyslennosti
title: Контрольный список № ЦТ. 0: Наилучшие доступные
titleType: AlternativeTitle
Creators: name: Winkelmann-Oei, Gerhard
Publisher: name: My University
Year: 2016
Subjects: subject: Papierindustrie
subject: Zellstoffindustrie
subject: Gewässerschutz
subject: Wasserverunreinigung
subject: Risikomanagement
subject: Leitfaden
subject: paper industry
subject: pulp industry
subject: pulp production
subject: water protection
subject: water pollution
subject: water pollutants
subject: risk management
subject: checklist
subject: guideline
subject: Chemikalien
subject: Chemicals

description: Diese branchenspezifischen Checklisten bilden einen Leitfaden für die Untersuchung und Beurteilung des Zustandes von Anlagen mit wassergefährdenden Stoffen und Zubereitungen in der Zellulose- und Papierindustrie. Dabei bieten sie eine Übersicht über die verschiedenen Handlungsfelder sowie einen nach Produktionsbereichen aufgeteilten Bereich um potentielle Risikoquellen und Modernisierungsziele zu identifizieren. Quelle: Bericht
description: Эти отраслевые контрольные листы представляют собой руководство по проверке и оценке состояния установок с вредными для водных ресурсов материалами и растворами в целлюлозно-бумажной промышленности. При этом они предлагают обзор различных сфер деятельности, а также сферы, разделенной по производственным отраслям, для идентификации потенциальных источников риска и целей модернизации.
School days: '2:37'
Creators: name: McFarlane, Brian
Publisher: name: Swinburne
Year: 2024

description: Somehow I failed to see Gus Van Sant's Elephant (2003) to which virtually every reviewer of '2:37' has drawn attention, almost as if it constituted some sort of hypotext from which Murali K. Thalluri's compelling feature has sprung.
Acts and Consequences: An Analysis of Modern Act-Consequentialism
Creators: name: Chandler-Haines, Cameron
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016

description: In this thesis I look at the modern state of Act-Consequentialism and how it can defend against five of the more prominent objections found in recent literature on the topic. The five objections are as follows: AC’s neglect of special personal relationships, its overdemandingness, its inability to handle expectation effects, its incompatibility with the claims of justice, and its suppression of our moral integrity. Although each of these objections differ significantly from one another, and this leads to separate treatment of each by chapter, all the objections deal on some level with the “derivativeness” of Act-Consequentialist moral thought when analyzing questions of a seemingly intrinsic quality, such as special personal relations or the dictates of justice. The approach taken towards the objections is broadly similar. By carefully considering the nature of the well-being that is promoted under AC, and how to most efficiently and organically promote it, the most severe aspects of the objections are softened. In working through the objections it is hoped that a more plausible form of Act-Consequentialism, with a stress on organic and efficient well-being promotion, will emerge.
The Effects of the Female Reproductive Hormones on Ovarian Cancer Initiation and Progression in a Transgenic Mouse Model of the Disease
Creators: name: Laviolette, Laura
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: ovarian cancer
mouse model
17β-estradiol
progesterone
ovarian surface epithelium
menopause
VCD
follicle stimulating hormone
luteinizing hormone

description: Ovarian cancer is thought to be derived from the ovarian surface epithelium (OSE), but it is often diagnosed during the late stages and therefore the events that contribute to the initiation and progression of ovarian cancer are poorly defined. Epidemiological studies have indicated an association between the female reproductive hormones and ovarian cancer etiology, but the direct effects of 17β-estradiol (E2), progesterone (P4), luteinizing hormone (LH) and follicle stimulating hormone (FSH) on disease pathophysiology are not well understood. A novel transgenic mouse model of ovarian cancer was generated that utilized the Cre/loxP system to inducibly express the oncogene SV40 large and small T-Antigen in the OSE. The tgCAG-LS-TAg mice developed poorly differentiated ovarian tumours with metastasis and ascites throughout the peritoneal space. Although P4 had no effect; E2 significantly accelerated disease progression in tgCAG-LS-TAg mice. The early onset of ovarian cancer was likely mediated by E2’s ability to increase the areas of putative preneoplastic lesions in the OSE. E2 also significantly decreased survival time in ovarian cancer cell xenografts. Microarray analysis of the tumours revealed that E2 mainly affects genes involved in angiogenesis and cellular differentiation, proliferation, and migration. These results suggest that E2 acts on the tumour microenvironment in addition to its direct effects on OSE and ovarian cancer cells. In order to examine the role of the gonadotropins in ovarian cancer progression, the tgCAG-LS-TAg mice were treated with 4-vinylcyclohexene-diepoxide (VCD) to induce menopause. Menopause slowed the progression of ovarian cancer due to a change in the histological subtype from poorly differentiated tumours to Sertoli tumours. Using a transgenic mouse model, it was shown that E2 accelerated ovarian cancer progression, while P4 had little effect on the disease. Menopause (elevated levels of LH and FSH) altered the histological subtype of the ovarian tumours in the tgCAG-LS-TAg mouse model. These results emphasize the importance of generating animal models to accurately recapitulate human disease and utilizing these models to develop novel prevention and treatment strategies for women with ovarian cancer.
Beyond Doctrines of Dominance: Conceptualizing a Path to Legal Recognition and Affirmation of the Manitoba Métis Treaty
Creators: name: Vermette, D'Arcy G.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: subject: Manitoba
subject: Metis
subject: Métis
subject: half-breed
subject: Manitoba Act, 1870
subject: Manitoba Act
subject: Law
subject: FOS: Law
subject: Treaty
subject: Treaty law
subject: Constitution

description: In 1869-70 the Métis of the Red River region in Manitoba resisted the transfer of their homeland from the Hudson’s Bay Company to Canada. The Métis people responded to this transfer by blocking Canadian surveyors, government officials, and taking control of the territory through the establishment of representative institutions. Eventually, the Métis negotiated favourable terms with Ottawa which, this thesis argues, represented according to law, and to the Métis, a treaty. This thesis argues that this treaty was intended to protect the Métis homeland and provide political and social protections. The Manitoba Métis Treaty was intended to guarantee the Métis a land base in Manitoba the total size of which was to be 1.4 million acres. The reservation of this land came with protective obligations so that the entire community would receive a benefit from such lands. While Canada has developed a body of treaty law which will be used to interpret the Manitoba Métis Treaty, matters were convoluted by the enshrinement of this treaty agreement in the Manitoba Act of 1870, a document which would gain constitutional status a year later. The impact of this legislative history has led some researchers to link government obligations entirely to the Act, rather than to the negotiated agreement. Indeed, it would seem that the negotiations have been, for the most part, understood as nothing more than conversations. I reject that position and argue that both the negotiations and the Act must be taken into consideration when assessing the obligations undertaken by the Crown. The unique history of the Manitoba agreement means that Canada was under both constitutional and treaty law obligations to uphold the negotiated agreement between itself and the Métis. This thesis argues that not only is the treaty the correct legal interpretation of the events of 1869-70 but that the government of Canada failed to honour its commitments in several meaningful ways. The approach utilized in this thesis is designed to be reliant upon the basic structure and doctrines of Canadian law but to do so in a manner which gives weight to the Métis voice. It is neither a critique which is wholly internal to Canadian law nor is it completely dismissive of Canadian law. Instead, this thesis will illustrate that with only minor adjustments to the application and interpretation of colonial law, the Manitoba Métis Treaty could find a more receptive audience in Canadian legal thought. In the face of a reasonable alternative, such a project can allow other researchers to question why the courts have chosen a path which denies reception of Métis voice, community and culture in Canadian law.
Quantification of Changes for the Milne Ice Shelf, Nunavut, Canada, 1950 - 2009
Creators: name: Mortimer, Colleen Adel
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Ice Shelf
Arctic change
Nunavut
Glaciology
Ground penetrating radar
Ellesmere Island

description: This study presents a comprehensive overview of the current state of the Milne Ice Shelf and how it has changed over the last 59 years. The 205 ±1 km2 ice shelf experienced a 28% (82 ±0.8 km2) reduction in area between 1950 – 2009, and a 20% (2.5 ±0.9km3 water equivalent (w.e.)) reduction in volume between 1981 – 2008/2009, suggesting a long-term state of negative mass balance. Comparison of mean annual specific mass balances (up to -0.34 m w.e. yr-1) with surface mass balance measurements for the nearby Ward Hunt Ice Shelf suggest that basal melt is a key contributor to total ice shelf thinning. The development and expansion of new and existing surface cracks, as well as ice-marginal and epishelf lake development, indicate significant ice shelf weakening. Over the next few decades it is likely that the Milne Ice Shelf will continue to deteriorate.
Theorizing Ambush Marketing in the Olympic Games
Creators: name: Ellis, Dana L.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Olympic Games
Ambush Marketing
Institutional Theory
Network Theory
Sponsorship
Mega-events

description: This research comprises three interconnected studies that, when considered together, attend to the dissertation’s purpose of presenting an integrated conceptual framework for ambush marketing in the Olympic Games. This has been accomplished in two ways: (1) the use of institutional theory, supported by network theory, as a lens to view and understand evolutionary processes in Olympic sponsorship and ambush marketing and (2) the use of grounded theory to build a conceptual framework of ambush marketing from the findings. Broadly, the model suggests the evolution of ambush marketing is partially impacted by, and an outcome of, institutional forces and considerations. Study I examines the process of institutionalization in the evolution of Olympic sponsorship during its most critical period of growth. It is argued that three key periods of change for sponsorship and two for ambush marketing exist during this time. Furthermore, these periods of change, most specifically concerning anti-ambush marketing practices, suggest the institutionalization of anti-ambush marketing legislation in the Olympic Games. Study II examines how Olympic ambush marketing stakeholder power and transfer of sponsorship and ambush marketing knowledge has influenced institutional processes toward the state of anti-ambush legislation as institutionalized brand protection. Centrality measures suggest the International Olympic Committee and Organizing Committees for the Olympic Games demonstrate the greatest stakeholder influence within the Olympic ambush marketing network. It is further argued the influence resulting from the structure of Olympic ambush marketing networks impacts the institutional processes of objectification and sedimentation. Study III examines the contemporary state of Olympic sponsorship evidenced by institutionalized legislated brand protection. While direct marketing implications of anti-ambush marketing legislation are minimal, it is argued the practice represents a portion of a regime of brand protection and that public relations outcomes of legislated brand protection must be carefully managed as part of a brand management strategy. Similarly, proportionality and managing expectations are arguably important in the understanding and application of such laws. Finally it is suggested that while the Olympic Movement may be viewed as an early adopter of anti-ambush legislation in the mega-event field, the individual character of each Olympic Games will interfere with complete isomorphism.
Data Driven Selective Sensing for 3D Image Acquisition
Creators: name: Curtis, Phillip
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Selective Sensing
3D Imaging
Sensing
Machine Vision
Intelligent Sensing
Probabilistic Occupancy Grid
Range images
Kriging

description: It is well established that acquiring large amounts of range data with vision sensors can quickly lead to important data management challenges where processing capabilities become saturated and pre-empt full usage of the information available for autonomous systems to make educated decisions. While sub-sampling offers a naïve solution for reducing dataset dimension after acquisition, it does not capitalize on the knowledge available in already acquired data to selectively and dynamically drive the acquisition process over the most significant regions in a scene, the latter being generally characterized by variations in depth and surface shape in the context of 3D imaging. This thesis discusses the development of two formal improvement measures, the first based upon surface meshes and Ordinary Kriging that focuses on improving scene accuracy, and the second based upon probabilistic occupancy grids that focuses on improving scene coverage. Furthermore, three selection processes to automatically choose which locations within the field of view of a range sensor to acquire next are proposed based upon the two formal improvement measures. The first two selection processes each use only one of the proposed improvement measures. The third selection process combines both improvement measures in order to counterbalance the parameters of the accuracy of knowledge about the scene and the coverage of the scene. The proposed algorithms mainly target applications using random access range sensors, defined as sensors that can acquire depth measurements at a specified location within their field of view. Additionally, the algorithms are applicable to the case of estimating the improvement and point selection from within a single point of view, with the purpose of guiding the random access sensor to locations it can acquire. However, the framework is developed to be independent of the range sensing technology used, and is validated with range data of several scenes acquired from many different sensors employing various sensing technologies and configurations. Furthermore, the experimental results of the proposed selection processes are compared against those produced by a random sampling process, as well as a neural gas selective sensing algorithm.
Analysis of Pipeline Systems Under Harmonic Forces
Creators: name: Salahifar, Raydin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: Thin Shells
Harmonic Forces
Finite Element
Closed-form Solution
Circular Cylindrical Thin Shell
Toroidal Thin Shell
Fourier Series
Tensor Calculus
Pipeline Systems
Pipe
Pipe Bend
Elbow

description: Starting with tensor calculus and the variational form of the Hamiltonian functional, a generalized theory is formulated for doubly curved thin shells. The formulation avoids geometric approximations commonly adopted in other formulations. The theory is then specialized for cylindrical and toroidal shells as special cases, both of interest in the modeling of straight and elbow segments of pipeline systems. Since the treatment avoids geometric approximations, the cylindrical shell theory is believed to be more accurate than others reported in the literature. By adopting a set of consistent geometric approximations, the present theory is shown to revert to the well known Flugge shell theory. Another set of consistent geometric approximations is shown to lead to the Donnell-Mushtari-Vlasov (DMV) theory. A general closed form solution of the theory is developed for cylinders under general harmonic loads. The solution is then used to formulate a family of exact shape functions which are subsequently used to formulate a super-convergent finite element. The formulation efficiently and accurately captures ovalization, warping, radial expansion, and other shell behavioural modes under general static or harmonic forces either in-phase or out-of-phase. Comparisons with shell solutions available in Abaqus demonstrate the validity of the formulation and the accuracy of its predictions. The generalized thin shell theory is then specialized for toroidal shells. Consistent sets of approximations lead to three simplified theories for toroidal shells. The first set of approximations has lead to a theory comparable to that of Sanders while the second set of approximation has lead to a theory nearly identical to the DMV theory for toroidal shells. A closed form solution is then obtained for the governing equation. Exact shape functions are then developed and subsequently used to formulate a finite element. Comparisons with Abaqus solutions show the validity of the formulation for short elbow segments under a variety of loading conditions. Because of their efficiency, the finite elements developed are particularly suited for the analysis of long pipeline systems.
The Influence of Traditions and Cultural Norms on Girls’ School Withdrawal in Afghanistan: A Qualitative Study of Maternal Accounts
Creators: name: Qayuome Hareer, Diba
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Girls' school withdrawal
Traditions and cultural norms
Hoftstede's Cultural Dimensions Model
Existentialist Feminism Theory

description: Girls’ withdrawal from school is posing a major challenge to female literacy in Afghanistan. The aim of this research was to examine the influence of Afghan traditions and cultural norms on girls’ school withdrawal by parents or guardians in Khinjan District of Baghlan Province. To achieve this aim the accounts of 12 mothers with daughters pulled out of school were obtained through semi-structured interviews and analyzed via the theoretical lens of Existentialist Feminism and Hofstede’s Cultural Dimensions Model. The findings suggest that in order to address the problem of girls’ withdrawal from school in Khinjan, the informal communication networks that reinforce the tendency of parents/guardians, especially male ones, to withdraw the girls from school should be influenced by communication channels in the district. Grounded on Paulo Freire’s concept of dialogue for liberation, it is recommended that credible members in the community should initiate and engage in a transforming dialogue about education of girls, with Khinjanis.
Behavioural and cognitive experiments previously conducted. from Remote islands as natural laboratories: human-food association increases attraction to humans and novelty exploration in a seabird
Creators: name: Danel, Samara
name: Belle, Solenne
name: Rebout, Nancy
name: Caro, Samuel
name: Bonadonna, Francesco
name: Biro, Dora
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310901
subject: Animal behaviour

description: Summary table of experiments conducted from 2019 to 2023 at île Verte, where at least one individual within each breeding pair participated in experiments. Grey colour indicates which pair participated in experiments.
Quand les mots se heurtent aux maux: Portait d’un discours morcelé. Étude de l’expérience subjective des personnes utilisatrices des services de santé mentale au Québec.
Creators: name: Larose-Hébert, Katharine
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: santé mentale
organisation des services
identité
expérience subjective
carrière morale

description: Cette recherche fut élaborée afin d’offrir un portrait contrasté et critique de l’organisation des services de santé mentale au Québec. Elle se situe en réaction contre la volonté instituée d’exclure la parole de la personne psychiatrisée et de la soustraire d’une partie de son pouvoir sur elle-même. Afin de découvrir la manière dont l’identité se transforme à travers le parcours de soins, nous avons développé un cadre conceptuel liant les théorisations goffmanienne et foucauldienne, nous permettant de mettre à jour la façon dont les discours dominants et l’organisation concrète des services agissent sur l’expérience sensible des sujets. Méthodologiquement, nous nous sommes inspirée des principes de l’ethnographie institutionnelle et avons effectué une collecte de données de 16 mois, par le bais de l’observation participante et d’entretiens semi-dirigés, au sein de trois organismes communautaires de santé mentale dans la ville de Gatineau. La population cible de cette recherche était composée d’adultes psychiatrisés faisant actuellement l’usage de leurs services. Nos résultats montrent que organisation de l’offre de services engendre des attributs identitaires chez les participants par le biais de contraintes structurelles qui occasionnent une transformation du rapport à soi, à l’autre et à la société. Ces contraintes résultent de relations de pouvoir se situant à l’extérieur de la vie quotidienne des usagers et sous-jacentes à l’organisation des services. Un continuum identitaire se développe au cours du parcours, aboutissant à son extrême, à une identité « docile » qui correspond aux besoins de fonctionnalité de la structure et qui contribue au maintien de relations de pouvoir asymétriques, au détriment de l’usager. Celui-ci demeure, ainsi, dans un état de marginalité institué. En tant que travailleuse sociale, nous proposons d’avoir recours à l’approche d’intervention visant la conscientisation critique des usagers, afin que ces derniers puissent contrer la modulation de soi et se réapproprier réellement leur pouvoir d’agir.
Is business planning pre-condition for the future success of immigrant entrepreneurs in Germany?
Creators: name: Fertala, Nikolinka
Publisher: name: Swinburne
Year: 2024

description: In this study, we challenge the negative view of business plan activities, arguing that business planning is not only a rational decision-taking instrument for potential entrepreneurs in the framework of startup capital constraints, but also an important precursor to action in new venture. We investigated both the production and the outcomes of written business plans following 647 immigrant entrepreneurs during a two-year period in the city of Colon. Our empirical findings show that institutional variables, such as coercive, mimetic and normative isomorphic pressure are significant predictors influencing the propensity to incline towards business plan activities. Interestingly, our results indicate that performance, measured by profitability and survival, is an outcome of organisational isomorphism.
Surface Directed Monoclonal Antibodies against STEC Aid in the Reduction of Pathogen Detection Times from Food and Water
Creators: name: Kumaran, Dilini
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2016
Subjects: Food
Filtration
FNAB
Immunomagnetic separation
polystyrene beads
Shiga toxin producing E. coli

description: The diagnostic methods implemented at the Canadian Food Inspection Agency for the detection of Shiga toxin producing E. coli (STEC) are time consuming and tedious, taking up to 5 days before a positive sample can be confirmed. The goal of this project was to streamline the detection procedure for serogroup O157 and 6 important non-O157 serogroups of STEC. Following a short enrichment step (4-6 hrs), two approaches were considered: (1) the filtration of enrichment culture through a gradient of filtration membranes (decreasing pore sizes), followed by capture using specific monoclonal antibody (mAb)-coated Dynabeads, and detection via fluorescence microscopy, (2) the addition of enrichment culture into a flow through system consisting of a column packed with large polystyrene beads (≥ 100 μm) coated with specific mAbs for capture. The results indicate that the filtration approach can only be applied to simpler food matrices. However, at least 100 CFU of the target STEC could be recovered using the filtration system following 4 hrs of enrichment of these matrices spiked with ≤ 15CFU of the target STEC. Similar capture results were obtained in the second approach using specific mAbs immobilized on covalently coupled protein G polystyrene beads and diluted enrichment media. A combination of these strategies together with immunofluorescence microscopy (IMS) and polymerase chain reaction (PCR) could provide diagnostic laboratories with a means to confirm a positive sample within 2 days of testing.
Molecular Mechanisms of Myogenesis in Stem Cells
Creators: name: Ryan, Tammy
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2011
Subjects: embryonic stem cells
myogenesis
transcription factor

description: Embryonic stem cells (ESCs) represent a promising source of cells for cell replacement therapy in the context of muscle diseases; however, before ESC-based cell therapy can be translated to the clinic, we must learn to modulate cell-fate decisions in order to maximize the yield of myocytes from this systems. In order to gain a better understanding of the myogenic cell fate, we sought to define the molecular mechanisms underlying the specification and differentiation of ESCs into cardiac and skeletal muscle. More specifically, the central hypothesis of the thesis is that myogenic signalling cascades modulate cell fate via regulation of transcription factors. Retinoic acid (RA) is known to promote skeletal myogenesis, however the molecular basis for this remains unknown. We showed that RA expands the premyogenic progenitor population in mouse stem cells by directly activating pro-myogenic transcription factors such as Pax3 and Meox1. RA also acts indirectly by activating the pro-myogenic Wnt signalling cascade while simultaneously inhibiting the anti-myogenic influence of BMP4. This ultimately resulted in a significant enhancement of skeletal myogenesis. Furthermore, we showed that this effect was conserved in human embryonic stem cells, with implications for directed differentiation and cell therapy. The regulation of cardiomyogenesis by the Wnt pathway was also investigated. We identified a novel interaction between the cardiomyogenic transcription factor Nkx2.5 and the myosin phosphatase (MP) enzyme complex. Interaction with MP resulted in exclusion of Nkx2.5 from the nucleus and inhibition of its transcriptional activity. Finally, we showed that this interaction was modulated by phosphorylation of the Mypt1 subunit of MP by ROCK, downstream of Wnt3a. Treatment of differentiating mouse ESCs with Wnt3a resulted in exclusion of Nkx2.5 from the nucleus and a subsequent failure to undergo terminal differentiation into cardiomyocytes. This likely represents part of the molecular basis for Wnt-mediated inhibition of terminal differentiation of cardiomyocytes. Taken together, our results provide novel insight into the relationship between myogenic signalling cascades and downstream transcription factors and into how they function together to orchestrate the myogenic cell fate in stem cells.
Additional file 1 of Factors influencing the use of video interpretation compared to in-person interpretation in hospitals: a qualitative study
Creators: name: Feiring, Eli
name: Westdahl, Stine
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1.
The Morphoregulatory Role of Thidiazuron: Metabolomics-Guided Hypothesis Generation for Mechanisms of Activity
Creators: name: Erland, Lauren Alexandra Elizabeth
name: Giebelhaus, Ryland T.
name: Victor, Jerrin M. R.
name: Murch, S. J. (Susan J.)
name: Praveen, Saxena K.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2020

description: Thidiazuron (TDZ) is a diphenylurea synthetic herbicide and plant growth regulator used to defoliate cotton crops and to induce regeneration of recalcitrant species in plant tissue culture. In vitro cultures of African violet thin petiole sections are an ideal model system for studies of TDZ-induced morphogenesis. TDZ induces de novo shoot organogenesis at low concentrations and somatic embryogenesis at higher concentrations of exposure. We used an untargeted metabolomics approach to identify metabolites in control and TDZ-treated tissues. Statistical analysis including metabolite clustering, pattern and pathway tools, logical algorithms, synthetic biotransformations and hormonomics identified TDZ-induced changes in metabolism. A total of 18,602 putative metabolites with extracted masses and predicted formulae were identified with 1412 features that were found only in TDZ-treated tissues and 312 that increased in response to TDZ. The monomer of TDZ was not detected intact in the tissues but putative oligomers were found in the database and we hypothesize that these may form by a Diels–Alder reaction. Accumulation oligomers in the tissue may act as a reservoir, slowly releasing the active TDZ monomer over time. Cleavage of the amide bridge released TDZ-metabolites into the tissues including organic nitrogen and sulfur containing compounds. Metabolomics data analysis generated six novel hypotheses that can be summarized as an overall increase in uptake of sugars from the culture media, increase in primary metabolism, redirection of terpene metabolism and mediation of stress metabolism via indoleamine and phenylpropanoid metabolism. Further research into the specific mechanisms hypothesized is likely to unravel the mode of action of TDZ and to provide new insights into the control of plant morphogenesis.
Evolutionary Status of Mitochondrial Ribosomal Protein Genes rps19 and rpl2 and their Transfer to the Nucleus in Grasses
Creators: name: Atluri, Sruthi
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Gene transfer
Ribosomal protein
Mitochondria
Brome
Grasses

description: Massive mitochondrial gene transfer to the nucleus occurred very early during eukaryotic evolution following endosymbiosis, and is still ongoing in plants. Tracking recent gene transfer events can give us insight into the evolutionary processes by which a transferred gene becomes functional in the nucleus and how its protein gets targeted back into the mitochondrion, where it is needed. Rps19 and rpl2 are two such ribosomal protein genes that are known to have been transferred to the nucleus, many times independently during flowering plant evolution. My research project focusses on determining the status and expression of rps19 and rpl2 in the mitochondrion and nucleus of selected grasses and in particular brome (close relative to agronomically important crops such as wheat, rye and barley). My results at the level of DNA and RNA (PCR and RT-PCR, respectively) show that the mitochondrial brome rpl2 copy is a pseudogene while its functional gene is in the nucleus. The brome mitochondrial genome has a copy of rps19 which is transcribed and C-U edited. Surprisingly, the brome nuclear genome also has functional copies of rps19.The targeting sequence for the nuclear rps19 gene was acquired from duplication of mitochondrial targeting heat shock protein (hsp70) presequence. Comparative analysis strongly suggests that a functional rps19 gene was transferred to the nucleus before rice and maize lineages split and now that brome rps19 has been found to be present in both compartments, this implies a transition stage of about 60 million years. Oats was found to have a functional rps19 copy in the nucleus and has a novel presequence due to lineage specific rearrangements and exon shuffling. Functional paralogous copies were found in wheat, and maize while barley lost one of the copy. Thus, following transfer, duplication of rps19 gene must have occurred in the ancestor of barley and wheat clade. Maize might have had a recent duplication or gene conversion events along its lineage as its paralogous copies are very similar to each other. More information is needed to determine if this duplication event extends to wheat-brome, wheat-oats or even before rice and maize split. Barley was also found to have a recent independent DNA mediated transfer in addition to the common transfer, as it possesses an unedited nuc-mt rps19 in its nuclear genome. This suggests that barley must also have had a transition stage for ~60MY and lost its mitochondrial copy very recently.
Leadership In Higher Education: Case Study Research of Canadian University Presidents with Unfinished Mandates
Creators: name: Cafley, Julie Meredith
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Higher education
Transitions
Leadership derailments
Organizational socialization
University leadership
Sensemaking
University presidents
Social capital

description: Within Canada, the ever-changing context of universities is paralleled by an increased number of unfinished presidential mandates, approximately 16 in the past ten years. “Never has Canadian university presidential leadership been under greater scrutiny than it is today” (MacKinnon, 2004, p. 132). The trend of an increasing number of unfinished mandates of university presidents in Canada leads to some important questions that require further exploration. Through an in-depth series of interviews with six of the 16 Canadian university presidents with unfinished mandates, this research dives deeply into leadership experiences and highlights patterns and trends within the individual trajectories leading to their shortened mandate. More precisely, the leaders’ transitional process within their presidential role is examined in order to gain insight into the challenges of transition, particularly for the person at the top of the organization. The findings are focused on the themes of board governance and communication, university transitions, relationships within the executive team, the role of the predecessor, and diversity and leadership. This dissertation contributes a unique piece of research to the higher educational literature, and also provides concrete recommendations to improve transitional practices for leaders within the higher education environment.
Supplementary Material from More allogrooming is followed by higher physiological stress in wild female baboons
Creators: name: Christensen, Charlotte
name: Bracken, Anna
name: O'Riain, Mannus Justin
name: Heistermann, Michael
name: King, Andrew James
name: Fürtbauer, Ines
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310901
subject: Animal behaviour

description: Supplementary_Material_GroomingfGC_20240523.docx
Linking remote sensing and geodiversity and their traits relevant to biodiversity
Creators: name: Lausch, Angela
name: Baade, Jussi
name: Bannehr, Lutz
name: Schweitzer, Christian
Publisher: name: My University
Year: 2019
Subjects: Fernerkundung
Erdbeobachtung
Bodenbeschaffenheit
Bodenfeuchtigkeit

description: In the face of rapid global change it is imperative to preserve geodiversity for the overall conservation of biodiversity. Geodiversity is important for understanding complex biogeochemical and physical processes and is directly and indirectly linked to biodiversity on all scales of ecosystem organization. Despite the great importance of geodiversity, there is a lack of suitable monitoring methods. Compared to conventional in-situ techniques, remote sensing (RS) techniques provide a pathway towards cost-effective, increasingly more available, comprehensive, and repeatable, as well as standardized monitoring of continuous geodiversity on the local to global scale. This paper gives an overview of the state-of-the-art approaches for monitoring soil characteristics and soil moisture with unmanned aerial vehicles (UAV) and air- and spaceborne remote sensing techniques. Initially, the definitions for geodiversity along with its five essential characteristics are provided, with an explanation for the latter. Then, the approaches of spectral traits (ST) and spectral trait variations (STV) to record geodiversity using RS are defined. LiDAR (light detection and ranging), thermal and microwave sensors, multispectral, and hyperspectral RS technologies to monitor soil characteristics and soil moisture are also presented. Furthermore, the paper discusses current and future satellite-borne sensors and missions as well as existing data products. Due to the prospects and limitations of the characteristics of different RS sensors, only specific geotraits and geodiversity characteristics can be recorded. The paper provides an overview of those geotraits. Quelle: https://www.mdpi.com
Additional file 2 of Subjective cognitive decline, anxiety symptoms, and the risk of mild cognitive impairment and dementia
Creators: name: Liew, Tau Ming
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Time line of the second sensitivity analysis.
In Situ Raman Spectroscopy of the Type Selective Etching of Carbon Nanotubes and Their Growth from C60 Seeds
Creators: name: Li-Pook-Than, Andrew
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Carbon nanotubes
Raman spectroscopy
Oxidation
Fullerenes
Nanostructures
Chemical vapor deposition
Metallicity
In situ technique

description: In situ Raman spectroscopy was used to explore etching of carbon nanotubes as well as their growth from C60. The thesis is in three parts: (1) C60 seed particles were partially oxidized in air and were used to grow carbon nanotubes and other nanocarbon structures. Seed oxidization was characterized by monitoring the evolution of the Raman Ag(2) peak and the D band, and oxidation temperature was found to be critical to nanotube growth. (2) To further explore oxidation, carbon nanotubes were thermally oxidized in air at different temperatures, while the evolution of different Raman bands was tracked. Etching dynamics and band intensity evolution were tracked in situ. Notably, metallic species were found to etch much more rapidly than semiconducting species of similar diameter. (3) To confirm and expand on this, a novel, simultaneous two-laser Raman spectroscopy setup was used to track the thermal oxidation of carbon nanotubes in O2 and CO2 gases at different temperatures. Metallic species were resonant with one laser line, while semiconducting species were resonant with the other, so changes to sample metallicity could be tracked unambiguously in two separate spectra. Again, metals were found to etch more rapidly. In situ Raman spectroscopy can track the evolution of nanotubes in real time and provide insight into processing. In general, detailed process monitoring like this can help in the development of selective synthesis and processing.
Electronic supplementary material from Hidden rivals: the negative impacts of dolphinfish on seabird foraging behavior
Creators: name: Koyama, Shiho
name: Goto, Yusuke
name: Furukawa, Seishiro
name: Maekawa, Takuya
name: Yoda, Ken
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 310901
subject: Animal behaviour

description: The details of the statistical analysis and analyzed data.