cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Zusammenfassung Workshop Und Umfrageergebnisse "Bedarf Und Anforderungen An Ressourcen Für Text Und Data Mining"
Creators: name: Sens, Irina
name: Katerbow, Matthias
name: Schöch, Christof
name: Mittermaier, Bernhard
Publisher: name: Zenodo
Year: 2015
Subjects: TDM; Text Mining; Data Mining; Text and Data Mining

description: Zusammenfassung des Workshops und Visualisierung der Umfrageerbegnisse der Umfrage "Bedarf und Anforderungen an Ressourcen für Text und Data Mining" der Schwerpunktinitiative "Digitale Information" der Allianz der deutschen Wissenschaftsorganisationen, Arbeitsgruppe Text und Data Mining
description: Rohdaten der Umfrageergebnisse siehe: http://dx.doi.org/10.5281/zenodo.32584
description: {"references": ["Die Umfrageergebnisse sind als Rohdaten hier abgelegt: http://dx.doi.org/10.5281/zenodo.32583"]}
One method for constructing exact solutions of equations of two-dimensional hydrodynamics of an incompressible fluid
Creators: name: Yurov, A. V.
name: Yurova, A. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We propose a simple algebraic method for constructing exact solutions of equations of two-dimensional hydrodynamics of an incompressible fluid. The problem reduces to consecutively solving three linear partial differential equations for a nonviscous fluid and to solving three linear partial differential equations and one first-order ordinary differential equation for a viscous fluid.
description: 9 pages, 5 figs
Optical and non-equilibrium properties of graphene = Optische und Nichtgleichgewichtseigenschaften von Graphen
Creators: name: Briskot, Ulf
Publisher: name: Karlsruhe
Year: 2015
Subjects: Graphen
Nichtgleichgewicht
Transport

description: Die vorliegende Dissertation befasst sich mit der theoretischen Beschreibung von Nichtgleichgewichts-Eigenschaften von Graphen. Dazu wird eine quantenkinetische Beschreibung der Dynamik der elektronischen Quasiteilchen in Graphen unter dem Einfluss externer optischer Felder und Coulomb-Wechselwirkung entwickelt. Als Anwendungen wird die Relaxation optisch angeregter Elektronen untersucht und eine effektive hydrodynamische Beschreibung des elektronischen Transports in Graphen abgeleitet.
Chiral expansion of the $π^0\rightarrowγγ$ decay width
Creators: name: Li, Bing An
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A chiral field theory of mesons has been applied to study the contribution of the current quark masses to the $π^0\rightarrowγγ$ decay width at the next leading order. $2\%$ enhancement has been predicted and there is no new parameter.
description: 9 pages
Additional file 7 of Improved analysis of (e)CLIP data with RCRUNCH yields a compendium of RNA-binding protein binding sites and motifs
Creators: name: Katsantoni, Maria
name: van Nimwegen, Erik
name: Zavolan, Mihaela
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 7. Review_history.
Microscopic description of cluster radioactivity in actinide nuclei
Creators: name: Warda, M.
name: Robledo, L. M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Cluster radioactivity is the emission of a fragment heavier than $α$ particle and lighter than mass 50. The range of clusters observed in experiments goes from $^{14}$C to $^{32}$Si while the heavy mass residue is always a nucleus in the neighborhood of the doubly-magic $^{208}$Pb nucleus. Cluster radioactivity is described in this paper as a very asymmetric nuclear fission. A new fission valley leading to a decay with large fragment mass asymmetry matching the cluster radioactivity products is found. The mass octupole moment is found to be more convenient than the standard quadrupole moment as the parameter driving the system to fission. The mean-field HFB theory with the phenomenological Gogny interaction has been used to compute the cluster emission properties of a wide range of even-even actinide nuclei from $^{222}$Ra to $^{242}$Cm, where emission of the clusters has been experimentally observed. Computed half-lives for cluster emission are compared with experimental results. The noticeable agreement obtained between the predicted properties of cluster emission (namely, clusters masses and emission half-lives) and the measured data confirms the validity of the proposed methodology in the analysis of the phenomenon of cluster radioactivity. A continuous fission path through the scission point has been described using the neck parameter constraint.
description: 19 pages, 15 figures
Additional file 1 of The effect of physical activity on sleep disturbance in various populations: a scoping review of randomized clinical trials
Creators: name: Huang, Hung-Hsin
name: Stubbs, Brendon
name: Chen, Li-Jung
name: Ku, Po-Wen
name: Hsu, Tai-Yi
name: Lin, Chia-Wei
name: Weng, Yi-Ming
name: Wu, Shih-Hao
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: Table S1. Quality Assessment of Controlled Intervention Studies (QACIS) of the included articles.
Metamagnetic transition in Ca$_{1-x}$Sr$_x$Co$_2$As$_2$($x$ = 0 and 0.1) single crystals
Creators: name: Ying, J. J.
name: Yan, Y. J.
name: Wang, A. F.
name: Xiang, Z. J.
name: Cheng, P.
name: Ye, G. J.
name: Chen, X. H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We report the magnetism and transport measurements of CaCo$_2$As$_2$ and Ca$_{0.9}$Sr$_{0.1}$Co$_2$As$_2$ single crystals. Antiferromagnetic transition was observed at about 70 K and 90 K for CaCo$_2$As$_2$ and Ca$_{0.9}$Sr$_{0.1}$Co$_2$As$_2$, respectively. Magnetism and magnetoresistance measurements reveal metamagnetic transition from an antiferromagnetic state to a ferromagnetic state with the critical field of 3.5 T and 1.5 T respectively along c-axis for these two materials at low temperature. For the field along ab-plane, spins can also be fully polarized above the field of 4.5 T for Ca$_{0.9}$Sr$_{0.1}$Co$_2$As$_2$. While for CaCo$_2$As$_2$, spins can not be fully polarized up to 7 T. We proposed the cobalt moments of these two materials should be ordered ferromagnetically within the ab-plane but antiferromagnetically along the c-axis(A-type AFM).
North Atlantic Right Whale Sighting Survey (NARWSS) and Right Whale Sighting Advisory System (RWSAS) 2013 results summary.
Creators: name: Khan, Christin Brangwynne
name: Duley, Peter
name: Glass, Allison H.
name: Gatzke, Jennifer
name: Cole, Timothy V. N.
Publisher: name: U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northeast Fisheries Science Center
Year: 2014
Subjects: subject: Right whales--Detection--Atlantic Coast (North America)--Observations.

description: During 2013 , NARWSS flew 185 hours over 48 surveys, including directed flights over right whales reported near Atlantis Canyon, Cultivator Shoal, Great South Channel, and Nantucket Sound. NARWSS detected 45 right whales (including possible duplicate sightings of the same individual), with 30 right whales sighted within survey blocks and 15 right whales sighted during transit to or from survey areas. Table 1 summarizes survey effort and right whale sightings by month. Figures 3a-d display the locations of right whales and survey effort by season. In 2013, NARWSS did not conduct aerial surveys from February - April or August - October. Figure 2 and Table 2 provide a comparison of NARWSS flights, flight hours, and right whale sightings from 2002 through 2013. In 2013, right whale sightings were an order of magnitude lower than in previous years (0.17 right whales per hour of survey effort in 2013 compared to the previous average of 1.47 right whales per hour of survey effort). Table 4 summarizes internal and external requests for NARWSS survey data.
Fuzzy Knowledge Representation, Learning and Optimization with Bayesian Analysis in Fuzzy Semantic Networks
Creators: name: Omri, Mohamed Nazih
Publisher: name: arXiv
Year: 2012
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: This paper presents a method of optimization, based on both Bayesian Analysis technical and Gallois Lattice, of a Fuzzy Semantic Networks. The technical System we use learn by interpreting an unknown word using the links created between this new word and known words. The main link is provided by the context of the query. When novice's query is confused with an unknown verb (goal) applied to a known noun denoting either an object in the ideal user's Network or an object in the user's Network, the system infer that this new verb corresponds to one of the known goal. With the learning of new words in natural language as the interpretation, which was produced in agreement with the user, the system improves its representation scheme at each experiment with a new user and, in addition, takes advantage of previous discussions with users. The semantic Net of user objects thus obtained by these kinds of learning is not always optimal because some relationships between couple of user objects can be generalized and others suppressed according to values of forces that characterize them. Indeed, to simplify the obtained Net, we propose to proceed to an inductive Bayesian analysis, on the Net obtained from Gallois lattice. The objective of this analysis can be seen as an operation of filtering of the obtained descriptive graph.
Die Hydrodynamik des Antriebssystems „Propeller-Düse-Leitapparat“
Creators: name: Tichý, Jaroslav
Publisher: name: TUHH Universitätsbibliothek
Year: 1969
Subjects: classificationCode: 52.00
subject: Maschinenbau, Energietechnik, Fertigungstechnik: Allgemeines

description: Die Hydrodynamik des Antriebssystems „Propeller-Düse-Leitapparat“
Independent determination of the systematic and random errors of the proper motions in the PPMXL catalog using quasars
Creators: name: Wu, Zhen-Yu
name: Ma, Jun
name: Zhou, Xu
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Using a sample of 117053 quasars identified in the PPMXL catalog, the systematic errors of the proper motions in the PPMXL catalog are estimated independently as -2.0 and -2.1 mas yr$^{-1}$ in $μ_α\cosδ$ and $μ_δ$, respectively. For objects with SDSS $r$ magnitude between 16.0 and 21.0 mag and SDSS $g-r$ color between -0.4 and 1.2, there are no obvious magnitude and color dependence in the systematic errors of the proper motions in the PPMXL catalog. The random errors of the proper motions in the PPMXL catalog change from $\sim4.0$ to $\sim8.0$ mas yr$^{-1}$ along with the increase of the magnitude of the objects. No color dependence in the random errors of the proper motions in the PPMXL catalog is found. There are obvious right ascension $α$ dependence of the systematic errors in both components of the proper motions in the PPMXL catalog. For quasars with declination $δ>0$, the systematic errors of $μ_δ$ in the PPMXL catalog increase linearly with $δ$ with a slope of 0.07 mas yr$^{-1}$ deg$^{-1}$. For comparison, using a subsample of quasars identified both in the PPMXL and SDSS DR7 catalogs, the systematic errors of the USNO-SDSS proper motions in the SDSS DR7 catalog are derived as 0.9 and 0.5 mas yr$^{-1}$ in $μ_α\cosδ$ and $μ_δ$, respectively. There are no obvious magnitude, color, and $α$ dependence in the systematic errors of the USNO-SDSS proper motions. For quasars with declination $δ>0$, the systematic errors of $μ_δ$ in the SDSS DR7 catalog increase linearly with $δ$ with a slope of 0.03. The random errors of the USNO-SDSS proper motions change from $\sim2.5$ to $\sim6.0$ mas yr$^{-1}$ along with the change of the magnitude and color of the objects.
description: 17 pages, 14 figures, Accepted for publication in PASP
Mortality determinations for Baleen whale stocks along the Gulf of Mexico, United States east coast, and Atlantic Canadian provinces, 2008-2012
Creators: name: Henry, Allison
name: Cole, Timothy V. N.
name: Hall, Lanni
name: Ledwell, Wayne
name: Morin, David Matthew
name: Reid, Andrew
Publisher: name: U.S. Department of Commerce, National Oceanic and Atmospheric Administration, National Marine Fisheries Service, Northeast Fisheries Science Center
Year: 2014
Subjects: subject: Baleen whales--Mortality--Effect of human beings on--Atlantic Coast (North America).

description: The Northeast Fisheries Science Center (NEFSC) developed criteria to evaluate reports of human-caused mortality to baleen whales. The criteria minimize the likelihood of incorrectly assigning whale mortalities t o human causes and provide a minimum count of human-caused events. This report describes determinations made for reports received from 2008 - 2012 involving North Atlantic right (Eubalaena glacialis), humpback (Megaptera novaeangliae), fin (Balaenoptera physalus), sei (B. borealis), blue (B. musculus), minke (B. acutorostrata), and Bryde's (B. edeni) whales observed in United States waters in the Gulf of Mexico, along the US eastern seaboard and in the Atlantic Canadian provinces. We confirmed a total of 3 00 mortalities: 60 (20%) caused by human interaction, 14 (5%) because of natural causes, and 236 (75%) which lacked sufficient evidence to determine cause of death. Of the human-caused mortalities, 32 were due to entanglement and 28 were vessel strike. These mortality numbers are minimum counts because of a low probability of detecting events and inadequate documentation to determine cause of death for the majority of events that are detected. Despite the minimum values, the mean annual confirmed human-caused mortality rate exceeds the Potential Biological Removal (PBR) value for 4 of the 7 stocks examined, including North Atlantic right, humpback, sei, and Bryde's whales. The true level of anthropogenic mortality to these stocks is greater than these minimum values, but the amount greater is unknown.
Additional file 2 of The effect of physical activity on sleep disturbance in various populations: a scoping review of randomized clinical trials
Creators: name: Huang, Hung-Hsin
name: Stubbs, Brendon
name: Chen, Li-Jung
name: Ku, Po-Wen
name: Hsu, Tai-Yi
name: Lin, Chia-Wei
name: Weng, Yi-Ming
name: Wu, Shih-Hao
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2: Table S2. Quality Assessment of Controlled Intervention Studies (QACIS) Criteria.
Information Society: Modeling A Complex System With Scarce Data
Creators: name: Olivera, Noemi L.
name: Proto, Araceli N.
name: Ausloos, Marcel
Publisher: name: arXiv
Year: 2012
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Information Theory (cs.IT)
subject: Social and Information Networks (cs.SI)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Considering electronic implications in the Information Society (IS) as a complex system, complexity science tools are used to describe the processes that are seen to be taking place. The sometimes troublesome relationship between the information and communication new technologies and e-society gives rise to different problems, some of them being unexpected. Probably, the Digital Divide (DD) and the Internet Governance (IG) are among the most conflictive ones of internationally based e-Affairs. Admitting that solutions should be found for these problems, certain international policies are required. In this context, data gathering and subsequent analysis, as well as the construction of adequate physical models are extremely important in order to imagine different future scenarios and suggest some subsequent control. In the main text, mathematical modelization helps for visualizing how policies could e.g. influence the individual and collective behavior in an empirical social agent system. In order to show how this purpose could be achieved, two approaches, (i) the Ising model and (ii) a generalized Lotka-Volterra model are used for DD and IG considerations respectively. It can be concluded that the social modelization of the e-Information Society as a complex system provides insights about how DD can be reduced and how the a large number of weak members of the IS could influence the outcomes of the IG.
description: 14 pages, 12 figures, prepared for the Proceedings of The V Meeting on Dynamics of Social and Economic Systems
Semi-leptonic and Non-leptonic $B$ meson decays to charmed mesons
Creators: name: Hui-feng, Fu
name: Guo-Li, Wang
name: Zhi-Hui, Wang
name: Xiang-Jun, Chen
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the semi-leptonic and non-leptonic $B$ weak decays which are governed by the $B\rightarrow D^{(*)}$ transitions. The branching ratios, CP asymmetries (CPA) and polarization fractions (FA) of non-leptonic decays are investigated in the factorization approximation. The $B\rightarrow D^{(*)}$ form factors are estimated in the Salpeter method. Our estimation on branching ratios generally agree with the existent experimental data. For CPA and polarizations, comparisons among the FA results, the perturbative QCD predictions and experimental data are made.
description: 8 pages, 1 figures, 5 tables
Analysing Ngs Data With Clinical Data In A Translational Medicine Setting: Transmart And Cbioportal
Creators: name: Bochove, Kees Van
Publisher: name: Zenodo
Year: 2015

description: The use of Next Generation Sequencing in Translational Medicine is very diverse, but falls into two basic categories: clinical applications and research. In both settings, the combination of sequencing data with patient data generates its own set of challenges both from a legal and operational as well as from a data management, storage and analytics perspective.
In this talk, the emergence of a number of popular open source platforms for analyzing genomics data in a translational setting will be discussed, specifically tranSMART and cBioPortal. Both tools are used by an increasing number of pharma companies and medical centers, and are popular in public-private consortia as a means to provide a common repository and analytics interface for clinical and genomics data, next to public repositories such as dbGaP and EGA.
The speaker is founder and CEO of The Hyve, a 30-person open source bioinformatics company with offices in Utrecht and Boston that provides professional support for open source software for bioinformatics, clinical and translational research.
An improved model of vector mesons in holographic QCD
Creators: name: Alvares, Raul
name: Hoyos, Carlos
name: Karch, Andreas
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We analyze the sector of dimension-three vector meson operators in the "hard wall" model of holographic QCD, including the vector and axial currents, dual to gauge fields in the bulk, and the tensor operator $\barψσ^{μν}ψ$, dual to a two-form field satisfying a complex self-duality condition. The model includes the effect of chiral symmetry breaking on vector mesons, that involves a coupling between the dual gauge field and the two-form field. We compute the leading logarithmic terms in the operator product expansion of two-point functions and the leading non-perturbative contribution to the tensor-vector correlator. The result is consistent with the operator product expansion of QCD. We also study the spectrum of vector mesons numerically.
description: 19 pages
Additional file 1 of Interaction between blood cadmium and lead concentration and physical activity on hypertension from the Korean national health and nutrition examination survey in 2008–2013
Creators: name: Kwon, Jeoung A
name: Kim, Byungmi
name: Kim, Eunji
name: Kwon, Kisung
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Supplementary Material 1
Gluon distribution in proton at soft and hard pp collisions
Creators: name: Lykasov, G. I.
name: Bednyakov, V. A.
name: Grinyuk, A. A.
name: Poghosyan, M.
name: Dolbilov, A. G.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We analyze the inclusive spectra of hadrons produced in $pp$ collisions at high energies in the mid-rapidity region within the soft QCD and perturbative QCD assuming the possible creation of the soft gluons at low intrinsic transverse momenta $k_t$. From the best description of the LHC data we found the parametrization of the unintegrated gluon distribution which at low $k_t$ is different from the one obtained within the perturbative QCD.
description: 10 pages, 5 figures. Talk given the 5th joint International HADRON STRUCTURE '11 Conference (HS'11), Tatransk\'a Strba, Slovakia, June 27th - July 1st, 2011
Combinatorial R-trees as generalized Cayley graphs for fundamental groups of one-dimensional spaces
Creators: name: Fischer, Hanspeter
name: Zastrow, Andreas
Publisher: name: arXiv
Year: 2011
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 20F65 (Primary), 20E08, 55Q52, 57M05, 55Q07 (Secondary)

description: In their study of fundamental groups of one-dimensional path-connected compact metric spaces, Cannon and Conner have asked: Is there a tree-like object that might be considered the topological Cayley graph? We answer this question in the positive and provide a combinatorial description of such an object.
description: 25 pages, 3 figures
Boletín Informativo/Newsletter 17
Creators: name: Centro de Investigaciones Sobre America del Norte (CISAN)
Publisher: name: Zenodo
Year: 2025
Subjects: Latinos por Trump
Dreamers
Asociación Internacional de Estudios Interamericanos
International Association of Inter-American Studies
REDAN

description: BOLETÍN INFORMATIVONEWSLETTERNúmero 17 • Number 17 Marzo de 2025 • March 2025

EDITORIAL / EDITORIAL

ÍNDICE / TABLE OF CONTENTS

PUBLICACIONES MIEMBROS REDAN | REDAN MEMBERS’ PUBLICATIONSArtículos publicados / Published Articles• “Efectos del crimen organizado sobre el desarrollo empresarial en la frontera noreste de México y Texas. Un análisis de percepción social”Artículos de opinión / Opinion Articles• Perspectivas de la integración económica en América del Norte ante la nueva administración de Donald Trump• Entre las ciencias sociales y las humanidades: investigar América del Norte desde la Universidad Nacional Autónoma de México

Reseñas / ReviewsLibros / Books• Un cambio de época, América del Norte y la intervención rusa en Ucrania. Geopolítica y nuevas dinámicas de la globalización

Proyectos de investigación y docencia /Research and Teaching Projects• Conferencia “¿Latinos por Trump? Deconstruyendo la inclusión selectiva”• Dreamers: voces trasnacionales.Conversatorio en el CISAN

Eventos / Events• Relatoría del Tercer Congreso Bienal de Estudios Norteamericanos“¿Futuro compartido?”, de la Red de Norteamericanistas (REDAN)• Relatoría del VIII Encuentro de la Asociación Internacional de Estudios Interamericanos/International Association of Inter-American Studies, en el Centro de

Investigaciones sobre América del Norte (CISAN-UNAM)

CONVOCATORIAS | CALLS FOR PAPERSFOROS ACADÉMICOS | ACADEMIC FORUMSCULTURA | CULTURELIBROS / REVISTAS | BOOKS / JOURNALS• Libros / books• Lecturas de descarga abierta /Open Access Readings 

LIGAS DE INTERÉS | LINKS OF INTERESTLA COYUNTURA EN NORTEAMÉRICA |CURRENT ISSUES IN NORTH AMERICA• Noticias / News• Documentos / Documents• Infografía / Infographics

OPINIONES DE EXPERTOS EN LOS MEDIOS DECOMUNICACIÓN | EXPERTS OPINIONS IN THE MEDIA
The Human Knockout Project: Identifying Loss Of Function Variants In Large Population Datasets
Creators: name: Karczewski, Konrad
Publisher: name: Zenodo
Year: 2015

description: Every human carries at least a hundred loss-of-function (LoF) variants predicted to severely disrupt the function of protein-coding genes, including many in the homozygous state. These variants represent ?experiments of nature? that can cast light on the function of currently uncharacterized human genes: indeed, much novel biology has already been learned from the involvement of rare LoF variants in severe Mendelian disease. Additionally, these variants have also proved valuable in identifying potential therapeutic targets: LoF variants in PCSK9have been causally linked to low LDL cholesterol levels, leading to the development of PCSK9 as a therapeutic target for cardiovascular disease.
However, discovering LoFs in the human population remains a significant challenge, as these variants are enriched for sequencing and annotation errors, and typically have very low frequency, confounding their discovery and interpretation. For this reason, large sample sizes are required to discover LoFs in every possible gene. Alternatively, two distinct strategies, the use of bottlenecked populations and populations with a high rate of consanguineous mating, are established to significantly enrich for discovery of homozygous rare LoF variants, effectively identifying ?knockout? humans.
To this end, we have developed an open-source tool, LOFTEE (Loss Of Function Transcript Effect Estimator), to annotate loss-of-function variants. In order to characterize the landscape of homozygous LoF variants (knockouts) across humans, we have applied LOFTEE to a number of large datasets from collaborative efforts, including over 91,000 exomes aggregated from a variety of rare and complex disease consortia, deeply phenotyped samples from Finnish national biobanks, and over 1,000 parentally-related individuals from the UK. We validate these methods using databases of known disease variants, and investigate the role of LoF variants on splicing by intersecting exomes with matched RNA-Seq data from over 500 individuals from the GTEx consortium. Finally, we describe the aggregation of these variants into a database of LoF variants, dbLoF, providing a resource for pharmaceutical development, transplant biology, and understanding of rare Mendelian diseases.
Non-Reproducability Of Large-Scale Drug Screening
Creators: name: Haibe-Kains, Benjamin
Publisher: name: Zenodo
Year: 2015

description: Cancer cell line studies have long been used to test efficacy of therapeutic agents and to explore genomic factors predictive of response. Despite numerous attempts, the search for robust biomarkers of drug response has been mostly unsuccessful, probably due to small sample size and potential noise in the pharmacogenomic data. There is therefore a dire need for assessing the quality and reproducibility of such valuable datasets, as well as for combining multiple independent studies to increase the sample size and consequently, the statistical power of biomarker discovery. Our comparative study of multiple large-scale pharmacogenomic datasets demonstrates the importance of standardization to increase the reproducibility of these valuable data. As our results suggest that high level of inconsistency in drug sensitivity data might be responsible to the lack of robustness of the derived biomarkers, I will discuss some approaches that could help address the key issue of data reproducibility.
Caloric curve of star clusters
Creators: name: Casetti, Lapo
name: Nardini, Cesare
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Self-gravitating systems, like globular clusters or elliptical galaxies, are the prototypes of many-body systems with long-range interactions, and should be the natural arena where to test theoretical predictions on the statistical behaviour of long-range-interacting systems. Systems of classical self-gravitating particles can be studied with the standard tools of equilibrium statistical mechanics, provided the potential is regularized at small length scales and the system is confined in a box. The confinement condition looks rather unphysical in general, so that it is natural to ask whether what we learn with these studies is relevant to real self-gravitating systems. In order to provide a first answer to this question we consider a basic, simple, yet effective model of globular clusters, the King model. This model describes a self-consistently confined system, without the need of any external box, but the stationary state is a non-thermal one. In particular, we consider the King model with a short-distance cutoff on the interactions and we discuss how such a cutoff affects the caloric curve, i.e. the relation between temperature and energy. We find that the cutoff stabilizes a low-energy phase which is absent in the King model without cutoff; the caloric curve of the model with cutoff turns out to be very similar to that of previously studied confined and regularized models, but for the absence of a high-energy gas-like phase. We briefly discuss the possible phenomenological as well as theoretical implications of these results.
description: 21 pages, 13 figures
Baudenkmale gefährdet – Baudenkmale gerettet
Creators: name: Oelwein, Cornelia
name: Schwarze-Neuß, Elisabeth
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2020

description: -
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 50 Nr. 2 (2009): Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Betty: Enabling Large Scale GNN Training with Batch Level Graph Partitioning
Creators: name: Shuangyan Yang
name: Minjia Zhang
name: Li, Dong
Publisher: name: Zenodo
Year: 2023
Subjects: large scale graph
graph neural networks
graph partition
redundancy reduction

description: This artifact includes the source codes and expected experimental data for replicating the evaluations in this paper.
 We implement figure 2 to denote the OOM situation of current advanced GNN training, and applied figure 10 to illustrate Betty break the memory wall. We implement memory consumption estimation during the workflow of Betty, shown in figure 5. We use figure 12 to denote the tendency of peak memory consumption and training time per epoch as the number of micro batches increases. And the model convergence is not impacted by Betty and micro-batch training can be proved by the figure 13.
 The framework of Betty is developed upon DGL(pytorch backend). The requirements: pytorch >= 1.7, DGL >= 0.7. The other software dependency include sortedcontainers, pyvis, pynvml, tqdm, pymetis, seaborn.
 Our experiments result denoted in paper were collected from the machine with a RTX6000 GPU(24 GB memory) and Intel(R) Xeon(R) Gold 6126 CPU @ 2.60GHz. You can use a different configuration with at least one GPU.
description: {"references": ["Wang, M. Y. (2019, January). Deep graph library: Towards efficient and scalable deep learning on graphs. In ICLR workshop on representation learning on graphs and manifolds."]}
Influence of shear viscosity on the correlation between the triangular flow and initial spatial triangularity
Creators: name: Chaudhuri, A. K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In a hydrodynamic model, with fluctuating initial conditions, the correlation between triangular flow and initial spatial triangularity is studied. The triangular flow, even in ideal fluid, is only weakly correlated with the initial triangularity. The correlation is largely reduced in viscous fluid. Elliptic flow on the other hand appears to be strongly correlated with initial eccentricity. Weak correlation between triangular flow and initial triangularity indicate that a part of triangular flow is unrelated to initial triangularity. Triangularity acquired during the fluid evolution also contributes to the triangular flow.
description: 4 pages, 2 figures. arXiv admin note: text overlap with arXiv:1108.5552
Betty: Enabling Large-Scale GNN Training with Batch-Level Graph Partitioning
Creators: name: Shuangyan Yang
name: Minjia Zhang
name: Li, Dong
Publisher: name: Zenodo
Year: 2023
Subjects: large scale graph
graph neural networks
graph partition
redundancy reduction

description: Betty introduces two novel techniques, redundancy-embedded graph (REG) partitioning and memory-aware partitioning, to effectively mitigate the redundancy and load imbalances issues across the partitions. Redundancy-embedded graph (REG) is implemented in 'graph\_partitioner.py'; Memory-aware partitioning implementation is based on memory estimation, details are in 'block\_dataloader.py'
 In artifact evaluation, figure 2 illustrates the OOM situation of current advanced GNN training, and figure 10 shows Betty breaks the memory wall. We use figure 12 to denote the tendency of peak memory consumption and training time per epoch as the number of micro batches increases. Further, the model convergence is not impacted by Betty and micro-batch training can be proved by figure 13. The framework of Betty is developed upon DGL(pytorch backend). The requirements: pytorch >= 1.7, DGL >= 0.7. The other software dependency include sortedcontainers, pyvis, pynvml, tqdm, pymetis. Our experiments result denoted in paper were collected from the machine with a RTX6000 GPU(24 GB memory) and Intel(R) Xeon(R) Gold 6126 CPU @ 2.60GHz. You can use a different configuration with at least one GPU.
description: {"references": ["Wang, M. Y. (2019, January). Deep graph library: Towards efficient and scalable deep learning on graphs. In ICLR workshop on representation learning on graphs and manifolds."]}
Label Free Technologies To Study Interactions Of Human Adenosine A2A Receptor In Detergent And Membrane Environment
Creators: name: Huber, Sylwia
Publisher: name: Zenodo
Year: 2015

description: Membrane proteins represent relevant protein classes for pharmaceutical industry with G-protein coupled receptors (GPCRs) being the most important targets as they comprise more than fifty percent of all leading proteins investigated in drug discovery.
Biophysical investigation on isolated and purified membrane proteins is very challenging because of generally low expression levels in common expression systems and the inherent instability of membrane proteins in a non-native environment. Protein engineering with the aim to stabilize the protein in a relevant conformation represents a validated strategy to overcome such instability and to make membrane proteins available for investigations on a molecular level. However, detergent environment can lead to artefacts in the binding characteristic of membrane proteins. Therefore, developing of novel tools mimicking native-like environment is of high importance to study membrane proteins in physiologically relevant state. From the technology point of view it has a big impact to develop novel techniques which can be applied to study membrane proteins in their fully native and complex membrane environment.
We present comparison of binding studies performed with two label free technologies, Surface Plasmon Resonance (SPR) and a novel technology based on theBackscattering Interferometry (BSI). Interactions of antagonistic ligands with thermostabilized and truncated version of the human adenosine (A2A) G-protein coupled receptor investigated in a detergent purified and in a membrane bound state (cell membranes and lipidic nanodiscs) were used as a model system to evaluate influence of various environments of A2A receptor on ligand binding, and to compare binding parameters with SPR and BSI.
Dem Tod mehrfach entgangen- Françoise Frenkels Einblicke in die Flüchtlingsmaschinerie des Zweiten Weltkrieges
Creators: name: Eckel, Dominik
Publisher: name: AKMB-news: Informationen zu Kunst, Museum und Bibliothek
Year: 2020

description: AKMB-news: Informationen zu Kunst, Museum und Bibliothek, Bd. 25 Nr. 1 (2019): AKMB-news
Magnetic soft modes in the locally distorted triangular antiferromagnet alpha-CaCr2O4
Creators: name: Toth, S.
name: Lake, B.
name: Hradil, K
name: Guidi, T.
name: Rule, K. C.
name: Stone, M. B.
name: Islam, A. T. M. N.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In this paper we explore the phase diagram and excitations of a distorted triangular lattice antiferromagnet. The unique two-dimensional distortion considered here is very different from the 'isosceles'-type distortion that has been extensively investigated. We show that it is able to stabilize a 120° spin structure for a large range of exchange interaction values, while new structures are found for extreme distortions. A physical realization of this model is α-CaCr2O4 which has 120° structure but lies very close to the phase boundary. This is verified by inelastic neutron scattering which reveals unusual roton-like minima at reciprocal space points different from those corresponding to the magnetic order.
description: 5 pages, 3 figures and lots of spin-waves
Activation Of G-Protein-Coupled Receptors Correlates With The Formation Of A Continuous Internal Water Pathway
Creators: name: Shuguang Yuan
Publisher: name: Zenodo
Year: 2015

description: More than 800 human GPCRs allow the selective detection of extracellular signals as diverse as photons, odorants, flavors, nucleotides, hormones, neurotransmitters - revealing GPCRs fundamental role in signal transduction. As they regulate many central physiological processes and are thus implicated in many diseases, GPCRs are among the most important targets for modern medicines. In spite of this medical importance and the recent progress in elucidating the 3D structures of various GPCRs, central questions how these receptors recognize extracellular chemical signals and transfer them across the cellular membrane to finally evoke an intracellular response are largely unresolved at a molecular level, mainly because the different steps during signal transmission are not directly accessible by experiments. In this context we are concentrating on central questions of GPCR mediated cellular signalling using molecular dynamics simulations and structural modelling. Our work revealed for the first time, in atomic detail, the entire process of transmembrane signalling of various GPCRs: we found that ligand binding induces a series of conformational changes within a GPCR which opens a gate inside the receptor for water molecules entering the internal region of the receptor and subsequently driving conformational switches within the receptor which finally led to the activation of a G protein on the intracellular side of the receptor. The discovery of these internal water channels paved the way for novel approaches in drug development.
Reference:
1. Yuan S*, Palczewski K.; Peng Q, Kolinski M, Vogel H*, Filipek S*. (2015) Ligand specificity of the ?- and ?-opioid receptors, a matter of space. Angew. Chem. Int. Edt  DOI: 10.1002/anie.201501742R2
2. Yuan S*, Hu Z, Filipek S, Vogel H*. (2015) W2466.48 opens a gate for a continuous intrinsic water pathway during activation of the adenosine A2A receptor. Angew. Chem. Int. Edt 127(2),566-569
3. Yuan S*.; Filipek S.; Palczewski K.; Vogel H*. (2014) Activation of G-protein-coupled receptor correlates with the formation of a continuous internal water pathway.Nature Communication 5, 4377 DOI:10.1038/ncomms5733
4. Yuan S*.; Vogel H.; Filipek S*., (2013) The Role of Water Molecules and Sodium Ions in ?-opioid Receptor Activation. Angew. Chem. Int. Edt52(38) 10112-10115
Additional file 1 of Opioid prescribing among aged care residents during the first year of the COVID-19 pandemic: an analysis using general practice health records in Australia
Creators: name: Dai, Zhaoli
name: Raban, Magdalena Z.
name: Sezgin, Gorkem
name: McGuire, Precious
name: Datta, Shirmilla
name: Wabe, Nasir
name: Pearce, Christopher
name: Woodman, Richard
name: Georgiou, Andrew
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1: Supplementary Table 1. General practice standard consultation - Medicare Benefits Schedule (MBS) billing items. Supplementary Table 2. Association between demographic characteristics and opioid prescribing status from March to December 2019 - 2020 among the same residents (n=7,340) recorded in both years. Supplementary Table 3. Stratified analyses for the association between demographic characteristics and opioid prescribing status between 2019 and 2020, March to December. Supplementary Table 4. Stratified analyses for the association between demographic characteristics and opioid prescribing status between the state of New South Wales (NSW) and Victoria from March to December, 2019-2020.
Die Beschreibung der Trifelskapelle durch Joseph Freiherr von Laßberg 1786, 1829
Creators: name: Leistikow, Dankwart
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2020

description: -
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 46 Nr. 2 (2005): Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Conformal metrics on R^{2m} with constant Q-curvature and large volume
Creators: name: Martinazzi, Luca
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We study conformal metrics on R^{2m} with constant Q-curvature and finite volume. When m=3 we show that there exists V* such that for any V\in [V*,\infty) there is a conformal metric g on R^{6} with Q_g = Q-curvature of S^6, and vol(g)=V. This is in sharp contrast with the four-dimensional case, treated by C-S. Lin. We also prove that when $m$ is odd and greater than 1, there is a constant V_m>\vol (S^{2m}) such that for every V\in (0,V_m] there is a conformal metric g on R^{2m} with Q_g = Q-curvature of S^{2m}, vol(g)=V. This extends a result of A. Chang and W-X. Chen. When m is even we prove a similar result for conformal metrics of negative Q-curvature.
description: 17 pages
The Hyperactive L Dwarf 2MASS J13153094-2649513: Continued Emission and a Brown Dwarf Companion
Creators: name: Burgasser, Adam J.
name: Sitarski, Breann N.
name: Gelino, Christopher R.
name: Logsdon, Sarah E.
name: Perrin, Marshall D.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report new observations of the unusually active, high proper motion L5e dwarf 2MASS J13153094-2649513. Optical spectroscopy with Magellan/MagE reveals persistent nonthermal emission, with narrow H I Balmer, Na I and K I lines all observed in emission. Low-resolution near-infrared spectroscopy with IRTF/SpeX indicates the presence of a low-temperature companion, which is resolved through multi-epoch laser guide star adaptive optics imaging at Keck. The comoving companion is separated by 338 \pm 4 mas, and its relative brightness (ΔK_s = 5.09 \pm 0.10) makes this system the second most extreme flux ratio very low-mass binary identified to date. Resolved near-infrared spectroscopy with Keck/OSIRIS identifies this companion as a T7 dwarf. The absence of Li I absorption in combined-light optical spectroscopy constrains the system age to >~0.8-1.0 Gyr, while the system's kinematics and unusually low mass ratio (M_2/M_1 = 0.3-0.6) suggests that it is even older. A coevality test of the components also indicates an older age, but reveals discrepancies between evolutionary and atmosphere model fits of the secondary which are likely attributable to poor reproduction of its near-infrared spectrum. With a projected separation of 6.6 \pm 0.9 AU, the 2MASS J13153094-2649513 system is too widely separated for mass exchange or magnetospheric interactions to be powering its persistent nonthermal emission. Rather, the emission is probably chromospheric in nature, signaling an inversion in the age-activity relation in which strong magnetic fields are maintained by relatively old and massive ultracool dwarfs.
description: 15 pages, accepted for publication in Astrophysical Journal
G Protein-Coupled Receptor Structures And Their Implications For Structure-Based Drug Discovery
Creators: name: Veli-Pekka Jaakola
Publisher: name: Zenodo
Year: 2015

description: Heptahelical receptors aka G protein coupled receptors, GPCRs, are the largest family of integral membrane proteins in the human genome and one of the most important targets for pharmaceutical industry. GPCRs are activated by a spectrum of structurally diverse ligands, and have been shown to modulate the activity of different G protein-dependent and G protein-independent signaling pathways in a ligand specific manner. In my presentation, I will summarize what is known about the structure and mechanism of activation of GPCRs primarily using adenosine receptor system as an example. I will discuss various structural features of human GPCRs including waters, ligands, lipids and co-factors, and their potential importance for receptor function and drug design.
Fünf nach Zwölf für Rathsfeld?
Creators: name: Laß, Heiko
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2020

description: -
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 46 Nr. 2 (2005): Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Einladung zum Kolloquium „Denkmal-Lobby Deutschland – wie viele Köche verderben den Brei?“ im Rahmen der exponatec Köln
Creators: name: Die Redaktion
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2020

description: -
description: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 50 Nr. 3 (2009): Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege