cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A universal approach to plague epidemics in fifteenth century Mamluk Egypt and Syria: contemporary bias, classical Islamic medicine and the voices of the Ulama
Creators: name: Koskella, Melaine Alexxann
Publisher: name: University of Utah
Year: 2014
Subjects: Black death
Egypt
Mamluk
Medieval medicine
Plague
Syria

description: Arabic historical narratives from fifteenth century Egypt allow a holistic exploration of the parallels and dichotomies inherent in debates regarding plague epidemics and etiology, classical Islamic medicine, and the fluid and yet precarious societal position of the ulama as historians of these epidemics. In a tenuous relationship, the ulama were bound not only to the sultan and his key associates for their livelihood, but also to the general population, over whom they exerted influence. Plague epidemics were recorded in the scholars' narratives, reflecting the narrative voice of the ulama, their varying social networks, the context in which they acted, and the literary traditions of the period. Previous research concerning plague epidemics in Mamluk Egypt has too narrowly focused on a so-called rigid religious orthodoxy, and the rise and decline of the Golden Age of Islam paradigm. However, classical scholars were a loosely formed, but dynamic group of individuals from various walks of life who interpreted their society, and through their written narratives, asserted their independence. These authors worked during difficult times to record plague epidemics and relate events critical for their understanding of Islamic Tradition, classical medicine and people's fear, misery and hope. Previous research has incorrectly portrayed these historical narratives as static and repetitive, confined by both Mamluk patronage and an undefined "Islam."
Sonnenfleckenzeichnung Nr. 22382.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.12.1966, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Skeletal muscle fatigue in health and disease: the role of active muscle mass, afferent feedback and oxidative stress
Creators: name: Rossman, Matthew J.
Publisher: name: University of Utah
Year: 2012

description: The overall objective of this thesis was to examine skeletal muscle function and the development of peripheral quadriceps fatigue in health and in patients with chronic obstructive pulmonary disease (COPD). The aim of the first study was to further elucidate the role of afferent feedback in the regulation of locomotor muscle fatigue during dynamic exercise by varying the amount of active muscle mass. Utilizing cycling (BIKE) and single-leg knee extensor (KE) exercise, far greater quadriceps fatigue at exhaustion was observed following KE exercise. These data imply that when the source of skeletal muscle afferent feedback is confined to a small muscle mass, the central nervous system tolerates a greater magnitude of peripheral fatigue, and likely a greater intramuscular metabolic disturbance; a finding that has important implications for the adoption of small muscle mass exercise in rehabilitative medicine. The second study sought to determine the impact of an acute oral antioxidant cocktail (AOC), with previously documented efficacy, on free radical concentration and KE exercise performance in patients with COPD. In this population, recognized to have elevated oxidative stress, administration of the AOC significantly attenuated resting free radical levels, which were negatively correlated with the degree of airflow limitation and baseline MVC force. Upon secondary analysis, however, a dichotomous response to the AOC was recognized, whereby the AOC appeared to be most efficacious in those patients with high initial free radical levels, with minimal effects when the initial free radical load was low. Despite these antioxidant effects, no differences in KE exercise performance or the magnitude of peripheral quadriceps fatigue were evident following consumption of the AOC. These findings revealed that acutely reducing free radicals with an oral AOC does not translate to improved exercise capacity and fatigue resistance in patients with COPD. Collectively, this research has provided novel insight into the role of active muscle mass and the regulation of peripheral fatigue, and has better elucidated the link between free radicals, antioxidants, and fatigue in patients with COPD.
Sonnenfleckenzeichnung Nr. 22261.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.07.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Novel model for predicting carpal tunnel syndrome and abnormal nerve conduction
Creators: name: Poulsen, Robert Parker
Publisher: name: University of Utah
Year: 2012
Subjects: CTS
Abnormal nerve conduction

description: Carpal Tunnel Syndrome (CTS) occurs with a relatively high prevalence in  manufacturing type facilities. The costs, both financial and human, associated with CTS  can be high. Prevention of CTS requires that risk factors be properly identified and  combined and/or ranked in order to direct the abatement process. Though it is known  that certain personal and physiological factors contribute to the development of CTS, a  strong, predictive correlation between job physical factors and CTS is still a developing  area.  A model was built to predict CTS and the related symptoms of numbness/tingling  in areas innervated by the median nerve and associated abnormal nerve conduction  outcomes. This model utilizes physical factors such as effort, intensity, detailed posture  components, "busy time," and efforts per minute among other observable physical job  attributes. Data were collected as part of a large prospective epidemiological study and  analyzed using the Utah Ergonomic Analysis (UEA) method and program.  Data suggest that the model as it currently stands has significant correlation with  outcome components, although it requires further development. Prediction of left hand  health outcomes is significant for most of the outcomes studied, but the prediction of  right hand outcomes was problematic. The predictive ability of personal and  physiological factors was reinforced. This paper discusses the development of this model, the data produced by the model, the findings resulting from the development  process, and the direction of future work in model development.
Sonnenfleckenzeichnung Nr. 22238.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.06.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
The life experience of the nurse preceptor: A hermeneutic phenomenological study
Creators: name: McDonald, Elizabeth M
Publisher: name: CQUniversity
Year: 2022
Subjects: subject: 130199 Education systems not elsewhere classified
subject: FOS: Educational sciences
subject: 130209 Medicine, Nursing and Health Curriculum and Pedagogy

description: The aim of this qualitative research project is to develop insight into and an interpretation of, the lived experiences of preceptors in clinical preceptorship programs for undergraduate nursing students. A framework based on hermeneutic phenomenology has been selected as the methodology to facilitate this research process. In depth interview technique is used for data generation from four selected preceptors from the same health care agency. Information shared by these preceptors is analysed within the hermeneutic framework. Evolving theme generation is documented and discussed with a view to enhanced insight into the phenomenon. Nurse educators, nurse managers, preceptors and students may use findings from this study to stimulate satisfying preceptorship experiences in an environment of collaborative nursing education. Other benefits relate to enhanced preceptor, preparation professional leadership programs that will engender positive professional attitudes and improved abilities of preceptors.
Solid state characterization, solubility, intrinsic dissolution and stability behavior of allopurinol hydrochloride salt
Creators: name: Barbosa, Thúlio Wliandon Lemos
name: Talmeli, Rafaela M. S.
name: de O., Homero
name: Doriguetto, Antônio C.
name: de Araújo, Magali B.
name: Bonfilio, Rudy
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Since each solid form of an active pharmaceutical ingredient (API) can exhibit particular physicochemical properties, the objectives of this work were to characterize and study the solubility/stability properties of allopurinol hydrochloride salt (ALO-HCl) for the first time. ALO-HCl was obtained through an unreported recrystallization process and studied by X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). All characterization techniques were effective for the differentiation of ALO-HCl from the preferred pharmaceutical form (ALO). DSC and TGA studies showed a solid-state conversion from ALO-HCl to ALO upon HCl loss. Solubility and dissolution tests showed that ALO-HCl converts to ALO in aqueous media. Moreover, the effect of the common ion decreased the amount of drug released from ALO-HCl during the intrinsic dissolution assay in HCl medium. The stability studies showed a partial conversion from ALO-HCl to ALO after 6 months of storage. The results indicate that comparative studies between crystalline forms of APIs are of great importance, as they contribute to the understanding of aspects related to the quality of medicines.
Variations of optical and radio lighting caracteristics and the relationship between storm convective intensity and above-cloud electric fields
Creators: name: Peterson, Michael Jay
Publisher: name: University of Utah
Year: 2014
Subjects: Atmospheric electricity
Lightning
LIP
LIS
TRMM

description: The optical properties of lightning observed by the Lightning Imaging Sensor (LIS) aboard the Tropical Rainfall Measuring Mission (TRMM) satellite between 1998 and 2010 are described and examined in the context of how they interrelate, when and where they occur globally, the nature of the cloud environment they illuminate, and the properties of the parent thunderstorm. Daytime (nighttime) flashes that occur over the open ocean are shown to be 31.7% (39.8%) larger and 55.2% (75.1%) brighter than flashes over land. Three factors are proposed that determine the size of the illuminated region: the brightness of the flash, the scattering properties of the cloud medium, and the structure of the electrical breakdown. Some of these results are explored using a Monte-Carlo radiative transfer model. The properties of TRMM Radar Precipitation Features (RPFs) that produce exceptionally large, long-lasting, and optically bright lightning flashes are compared to typical storms. RPFs over land with exceptionally large lightning flashes are up to three times larger than typical RPF thunderstorms and are considerably stronger. Coastal and oceanic RPFs with exceptionally large lightning flashes, as well as RPFs with exceptionally long lasting or bright flashes are also considerably larger and stronger than typical thunderstorms. Finally, high-altitude aircraft passive microwave and electric field observations taken by the NASA ER-2 over the course of multiple field campaigns are used to examine relationships between the properties of electrified clouds and above-cloud electric fields. A retrieval algorithm is created that is capable of estimating above-cloud electric fields from 85 GHz or 37 GHz passive microwave observations. The 37 GHz estimates are only valid over land since the ocean surface appears "cold" at 37 GHz and can reproduce the observed electric fields to within a factor of two 60% of the time. By comparison, the 85 GHz estimates fall within a factor of two of observations more than 70% of the time over land, but the 85 GHz routine is valid for both land and ocean cases. Individual cases are examined, and methods for improving the routine before applying it to satellite observations to study the Global Electric Circuit are discussed.
Analytical approach for lubricant characterization of excipients using the surface replication method
Creators: name: Saito, Shinichi
name: Osamura, Takashi
name: Tanino, Tadatsugu
name: Onoue, Satomi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Computational Biology

description: Lubricants are indispensable pharmaceutical ingredients for preventing tableting failure due to powder adhesion to the die wall. The impact of lubricants was evaluated with use of the Binding Identification for Net Detriment (BIND) surface replication method. Raloxifene hydrochloride (RH) was selected as a model chemical with high adhesion, and four commercially available tablet lubricants – stearic acid, sodium stearyl fumarate, calcium stearate, and magnesium stearate – were used for RH formulation. BIND was applied to the die wall to analyze the effect of various lubricants on binding properties. The preparations without lubricants showed poor tableting properties as evidenced by as much as 61.7% powder adhesion density. Lubricants significantly altered the binding properties, yielding powder adhesion densities of 40.2% (stearic acid), 29.7% (stearyl sodium fumarate), 23.0% (calcium stearate), and 13.6% (magnesium stearate). Evaluation of three grades of magnesium stearate resulted in a two-fold difference between the highest and the lowest powder adhesion density. Throughout the work, conventional methods including visual observations and measurement of ejection force were unable to provide qualitative/quantitative evaluations. The ejection process depends on both axial force and radial force; however, the ejection force show only the axial force. At the same time, visual observation could release significant qualitative results. However, BIND allowed qualitative and quantitative analysis of the binding properties. BIND is a promising assessment method for analyzing the impacts of various lubricants on binding properties and for optimizing RH formulations.
Sonnenfleckenzeichnung Nr. 22378.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.12.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Electrostatic deposition assisted preparation, characterization and evaluation of chrysin liposomes for breast cancer treatment
Creators: name: Deshmukh, Prashant K.
name: Mutha, Rakesh E.
name: Surana, Sanjay J.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Chrysin (CHR), a flavone found in multiple vegetables, fruits and mushrooms has been explored so far as a neurotropic, anti-inflammatory and anti-cancer biomolecule. Despite the stated therapeutic potential, low solubility and bioavailability limit its therapeutic benefit. To circumvent these drawbacks, development of chrysin liposomes (CLPs) is reported in the present investigation. The CLPs were developed by electrostatic deposition assisted film hydration method using chitosan/lecithin to protect chrysin in the nano-lipoidal shell. Developed CLPs were extensively characterized by DSC, XPRD, FE-SEM, TEM, particle size, polydispersity index, zeta potential, percent drug loading and encapsulation efficiency. These CLPs were further characterized by in vitro dissolution, in vivo bioavailability, in vitro anticancer and stability study. Suitable particle size, PDI and ZP implying stabilization of developed CLPs. The % DL and % EE was found to be 3.56 ± 0.13 and 90.5 ± 1.49 respectively. DSC and PXRD study revealed amorphous transition of CHR, which may help to increase its solubility and dissolution profile. In vivo pharmacokinetic study demonstrated more than 5-fold increase in relative bioavailability of CLPs. The in silico molecular docking study results demonstrated the electrostatic interaction between two polymers. The present study suggests that chitosan could protect and encapsulate chrysin which eventually enhances its cytotoxicity as well as bioavailability.
Spiritual embodiment of dance
Creators: name: Rooker, Rhonda Camille
Publisher: name: University of Utah
Year: 2012
Subjects: Dance, Religious aspects
Spirituality

description: Dance and spirituality are connected in many ways. Dance acts as a spiritual connection through worship in sacred contexts, portraying spiritual and religious content.  Movement and dance act as a catalyst to explore the inner witness, allowing the dancer to  develop a more conscious awareness of the embodied experience. They also connect all  of the components of the body, including the spiritual component, making the body a  spiritual vessel with which to manifest the mover's inner intent. This thesis investigates  these three connections in depth: dance as spiritual and religious portrayal, the inner  witness, and the mover as a spiritual vessel. It then discusses how these connections  informed two creative dance projects, which included three movement workshops that  explored spiritual beliefs through dance and culminated in a movement choir developed  with spiritual themes, and dance choreography exploring the relationship between an outer witness, or observer, and the inner witness.
title: Description of a Team-based Intensive Advising Mentor Program at An Undergraduate Baccalaureate Nursing Program: From the Advisers’ Perspective
Creators: name: Champlin, Barbara
name: Purfeerst, Christina
name: Engelhart, Anna
Publisher: name: The Pennsylvania State University Libraries
Year: 2015

description: The Mentor, Volume 17, ISSN: 1521-2211
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.10.1966, erstellt von Gisèle Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung Nr. 22299.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.08.1966, erstellt von Berthold Hermes
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22352.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.11.1966, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Hitler and Stalin: military command relationships and the couse of world war two on the eastern front
Creators: name: Carlson, Cody K
Publisher: name: University of Utah
Year: 2012
Subjects: Soviet Union Red Army
German Army
World War Two

description: This thesis examines the highest command relationships that existed in the Soviet  Union's Red Army and in the German Army just prior to and during the Second World  War. The roles of Hitler and Stalin as supreme military commander are considered in  relationship with their higher generals and how these relationships bore significantly on  the course of the war. Hitler's increasing micromanagement of the German war effort,  and Stalin's belated willingness to delegate military authority make up the central themes  of this work.  A variety of secondary sources, as well as generals' memoirs and diaries, point to  the conclusion that Hitler and Stalin were both military amateurs who possessed grand  strategic visions, but lacked the competent operational understanding of the trained  military technician. After the invasion of the Soviet Union, Hitler inserted himself  further and further down into the chain of command and directed tactical movements  from hundreds of miles away. By contrast, Stalin began the war dominating the Red  Army but gradually came to respect the abilities of his military specialists. Hitler's  disdain for his generals and Stalin's respect for his proved a major factor in the Soviet  victory in the Second World War.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.10.1966, als Blatt eröffnet dank auswärtiger Beobachtungen, ausgewertet in Zürich
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung bzw. Auswertung aufgrund auswärtiger Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen direkt auf dem Vordruck, erstellt durch Mitarbeitende der Eidgenössischen Sternwarte Zürich
Sonnenfleckenzeichnung Nr. 22324.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.09.1966, erstellt von Berthold Hermes
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22316.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.09.1966, erstellt von Berthold Hermes
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen
Development, validation and application of physiologically based biopharmaceutics model to justify the change in dissolution specifications for DRL ABC extended release tablets
Creators: name: Jaiswal, Swati
name: Ahmed, Tausif
name: Kollipara, Sivacharan
name: Bhargava, Mohit
name: Chachad, Siddharth
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Hematology

description: The generic drug product DRL ABC is an Extended Release (ER) Tablet manufactured by Dr. Reddy’s Laboratories Limited and have multi point dissolution as part of release specification. A proposal is being made to revise the dissolution specification and the aim of present work was to evaluate if this would still provide bioequivalent product. PBBM was developed for DRL ABC using literature reported pharmacokinetic (PK) data. The intravenous PK data and in vitro metabolic rate constants were utilized for developing PBPK model first, followed by that in conjugation with mechanistic ACATTM model, a PBBM is developed for per-oral immediate release formulations. The validated model was applied to predict clinical bioequivalence (BE) study data for the Reference (Innovator ER Tablet) and Test product. For Reference and Test product, in vivo dissolution profiles were mechanistically deconvoluted from plasma concentration (Cp)-time profiles. Further, mechanistic in vitro-in vivo relationship (IVIVR) applied to in vitro release profiles of two hypothetical Test product batches (one with single point low dissolution profile (SPLP) and other with overall low dissolution profile (LP)) in order to calculate their in vivo releases and population simulation was performed with 40 virtual subjects. Results from the cross-over virtual trials showed BE between the Reference and various Test product batches (SPLP and LP), with maximum Cp (Cmax) and area under the Cp-time curve (AUC0-inf) well within 80-125% range. PBBM in conjugation with IVIVR and virtual BE was successfully applied for justifying changes in dissolution specification of DRL ABC.
Shellac- a natural carrier for colon targeting of indomethacin using Hot melt extrusion
Creators: name: Kapote, Dnyaneshwar N.
name: Wagner, Karl G.
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Indomethacin (IND) is one of the supporting drug candidates for colonic targeting but it belongs to BCS class II category presenting a challenge in optimal targeting at the colonic site. To overcome this challenge, we sought to prepare a pH-dependent soluble ternary solid dispersion (SD) of IND of improved solubility and dissolution rate at the colon without the need for a coating. The current study focuses on the preparation of binary SDs of API (IND) with shellac (SSB 55) and Eudragit FS 100 (EFS) and ternary mixtures of IND, SSB 55 together with a new grade of HPMC (A15). Respective SDs were prepared via HME to achieve gastric protection and improved dissolution performance including maintenance of supersaturation. The SDs were characterized and tested for in-vitro dissolution performance using a pH shift dissolution method from 1.1, 5.5, 6.8, and 7.4. A ternary extrudate of IND, SSB 55, and A15 showed improved protection below pH 5.5 with a complete release of 99.5% at pH 7.4 compared to IND neat and binary extrudates from IND-A15, IND-SSB 55, and IND-EFS. It was attributed to an increased level of intermolecular interaction confirmed by ATR-IR and was studied for stability. It was found that in a ternary mixture containing IND, A15 and SSB 55 an increased hydrogen bonding interaction is present, which resulted in improved dissolution performance compared to binary mixtures. Therefore, ternary SDs proved to be a promising concept for future development of colon targeting of poorly soluble drugs.
Solid state characterization, solubility, intrinsic dissolution and stability behavior of allopurinol hydrochloride salt
Creators: name: Barbosa, Thúlio Wliandon Lemos
name: Talmeli, Rafaela M. S.
name: de O. Junior, Homero
name: Doriguetto, Antônio C.
name: de Araújo, Magali B.
name: Bonfilio, Rudy
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Since each solid form of an active pharmaceutical ingredient (API) can exhibit particular physicochemical properties, the objectives of this work were to characterize and study the solubility/stability properties of allopurinol hydrochloride salt (ALO-HCl) for the first time. ALO-HCl was obtained through an unreported recrystallization process and studied by X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). All characterization techniques were effective for the differentiation of ALO-HCl from the preferred pharmaceutical form (ALO). DSC and TGA studies showed a solid-state conversion from ALO-HCl to ALO upon HCl loss. Solubility and dissolution tests showed that ALO-HCl converts to ALO in aqueous media. Moreover, the effect of the common ion decreased the amount of drug released from ALO-HCl during the intrinsic dissolution assay in HCl medium. The stability studies showed a partial conversion from ALO-HCl to ALO after 6 months of storage. The results indicate that comparative studies between crystalline forms of APIs are of great importance, as they contribute to the understanding of aspects related to the quality of medicines.
Sonnenfleckenzeichnung Nr. 22254.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.07.1966, erstellt von Berthold Hermes
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Tata Kelola Jurnal Standar Akreditasi
Creators: name: Yunus, Muhammad
Publisher: name: Zenodo
Year: 2022
Subjects: ojs
tata kelola ojs
akreditasi jurnal

description: Materi Tata Kelola Jurnal Standar Akreditasi ini disampaikan pada acara Bimtek Pengelolaan Jurnal Constitution, Fakultas Syariah UIN KHAS Jember pada tanggal 18 Juli 2022.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.12.1966, erstellt am Kandilli Observatorium Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Kandilli Rasathanesi, Çengelköy (Istanbul). Instrument: Refraktor Teleskop (Öffnung 200 mm, f = 3070 mm, projiziertes Sonnenbild D = 25 cm).
Instrumentennachweis gemäss Kandilli Observatory Istanbul, Report from Solar Institute, in: Solar Physics, 1968, Vol. 3, Issue 3, pp.491-492, DOI: https://doi.org/10.1007/BF00171622
Development, validation and application of Physiologically Based Biopharmaceutics Model to justify the change in dissolution specifications for DRL ABC Extended release tablets
Creators: name: Jaiswal, Swati
name: Ahmed, Tausif
name: Kollipara, Sivacharan
name: Bhargava, Mohit
name: Chachad, Siddharth
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Hematology

description: The generic drug product DRL ABC is an Extended Release (ER) Tablet manufactured by Dr. Reddy’s Laboratories Limited and have multi point dissolution as part of release specification. A proposal is being made to revise the dissolution specification and the aim of present work was to evaluate if this would still provide bioequivalent product. PBBM was developed for DRL ABC using literature reported pharmacokinetic (PK) data. The intravenous PK data and in vitro metabolic rate constants were utilized for developing PBPK model first, followed by that in conjugation with mechanistic ACATTM model, a PBBM is developed for per-oral immediate release formulations. The validated model was applied to predict clinical bioequivalence (BE) study data for the Reference (Innovator ER Tablet) and Test product. For Reference and Test product, in vivo dissolution profiles were mechanistically deconvoluted from plasma concentration (Cp)-time profiles. Further, mechanistic in vitro-in vivo relationship (IVIVR) applied to in vitro release profiles of two hypothetical Test product batches (one with single point low dissolution profile (SPLP) and other with overall low dissolution profile (LP)) in order to calculate their in vivo releases and population simulation was performed with 40 virtual subjects. Results from the cross-over virtual trials showed BE between the Reference and various Test product batches (SPLP and LP), with maximum Cp (Cmax) and area under the Cp-time curve (AUC0-inf) well within 80-125% range. PBBM in conjugation with IVIVR and virtual BE was successfully applied for justifying changes in dissolution specification of DRL ABC.
Sonnenfleckenzeichnung Nr. 22332.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.10.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22289.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.08.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Design and control of a magnetic dipole source for noncontact manipulation
Creators: name: Petruska, Andrew J.
Publisher: name: University of Utah
Year: 2015
Subjects: Magnetic manipulation
Medical robotics
Omnimagnet
Teleoperation

description: This dissertation explores the design and use of an electromagnetic manipulation system that has been optimized for the dipole-eld model. This system can be used for noncontact manipulation of adjacent magnetic tools and combines the eld strength control of current electromagnetic systems with the analytical modeling of permanent-magnet systems. To design such a system, it is rst necessary to characterize how the shape of the eld source aects the shape of the magnetic eld. The magnetic eld generated by permanent magnets and electromagnets can be modeled, far from the source, using a multipole expansion. The error associated with the multipole expansion is quantied, and it is shown that, as long as the point of interest is 1.5 radii of the smallest sphere that can fully contain the magnetic source, the full expansion will have less than 1% error. If only the dipole term, the rst term in the expansion, is used, then the error is minimized for cylindrical shapes with a diameter-to-length ratio of 4=3 and for rectangular-bars with a cube. Applying the multipole expansion to electromagnets, an omnidirectional electromagnet, comprising three orthogonal solenoids and a spherical core, is designed that has minimal dipole-eld error and equal strength in all directions. Although this magnet can be constructed with any size core, the optimal design contains a spherical core with a diameter that is 60% of the outer dimension of the magnet. The resulting magnet's ability to dextrously control the eld at a point is demonstrated by rotating an endoscopic-pill mockup to drive it though a lumen and roll a permanent-magnet ball though several trajectories. Dipole elds also apply forces on adjacent magnetized objects. The ability to control these forces is demonstrated by performing position control on an orientation-constrained magnetic oat and nally by steering a permanent magnet, which is aligned with the applied dipole eld, around a rose curve.
An exploratory study of pedestrian crossing speeds at midblock crossing in India using LiDAR
Creators: name: Vasudevan, Vinod
name: Tiwari, Akhil
name: Chakroborty, Partha
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Understanding pedestrian road crossing behavior is essential from the perspectives of traffic flow and pedestrian safety. Limited research is available on pedestrian behavior in low- and middle-income countries. The main objective of this study is to understand pedestrian–vehicle interactions during midblock crossings in heterogeneous traffic conditions. Specifically, this study aims to understand whether pedestrians alter their crossing behavior depending on the type of approaching vehicles. To better understand pedestrian road crossing behavior at midblock crossings, an instrumented vehicle collected data from Kanpur, a large city in Uttar Pradesh, India. Because light detection and ranging provides point clouds at high frequency, an algorithm was developed to identify and track vehicles and pedestrians. Specifically, 2 types of interactions at midblock crossings were studied: car–pedestrian and motorized bike–pedestrian. The walking speed profiles and trajectories of the pedestrians were analyzed. The results show that pedestrians are more willing to engage in risky road crossing behavior in front of motorized bikes than in front of cars. Pedestrian walking speed profiles were unaffected by motorized bikes, but for cars, pedestrians tended to increase their speed in the first half of road crossing and then decrease in the second half. Pedestrian crossing speed profiles play an essential role in understanding pedestrian midblock crossing behavior. The speed data for pedestrians at various points of crossing are challenging to capture, but this study shows that LiDAR can be used to capture detailed pedestrian movements. The findings from this study demonstrate the importance of considering vehicle heterogeneity when analyzing pedestrian risk exposure and designing pedestrian crossing facilities.
Sonnenfleckenzeichnung Nr. 22306.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.09.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22368.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.11.1966, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22338.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.10.1966, erstellt von Berthold Hermes
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1966

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen