cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Phase de latence : ce que veulent les femmes
title: Phase de latence : ce que veulent les femmes
titleType: AlternativeTitle
Creators: name: Béral, Doriane
name: Dufaux, Mélanie
name: Ryser, Floriane
Publisher: name: Unknown
Year: 0
Subjects: subject: Labor
subject: Latent phase
subject: Satisfaction
subject: Experience

description: Problématique : La prise en soins de la phase de latence en obstétrique interroge autant les professionnels que les femmes. Bien qu’étudiée, il persiste des questionnements quant au lieu idéal de sa prise en soins, aux moyens à utiliser pour pallier à la douleur ainsi qu’en ce qui concerne la préparation des femmes et des couples durant la période prénatale. Sur la base de ces constats, une étude autour de la satisfaction des femmes en phase de latence semble pertinente. En effet, une bonne connaissance de leurs besoins permettrait d’adapter au mieux l'accompagnement sage-femme. Objectif : Cette revue de littérature a pour but d’identifier les éléments qui influencent la satisfaction des femmes au cours de la phase de latence, sur la base de leurs expériences. Méthodologie : Afin de réaliser cette revue de littérature, des recherches d’articles ont été effectuées sur les bases de données PubMed, CINAHL et MIDIRS. Au total, sept études ont été retenues. Cette revue de littérature comprend six articles de nature qualitative et un article quantitatif. Ceux-ci apportent des éléments de réponse à la problématique. Résultats : Les articles sélectionnés pour cette revue de littérature différencient les lieux où les femmes vivent la phase de latence : le domicile, le tri de la maternité et l’hôpital. Plusieurs éléments influencent la satisfaction de la femme en phase de latence, tels que la préparation anténatale, la présence et les interventions des professionnels, ainsi que le soutien des proches. Conclusion : Dans la pratique sage-femme, il est nécessaire de prendre en compte les éléments influençant la satisfaction des femmes, d’être à leur écoute et de les considérer comme uniques afin d’améliorer leur vécu de la phase de latence.
Determinantal Probability: Basic Properties and Conjectures
Creators: name: Lyons, Russell
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60K99, 60G55, 42C30, 37A15, 37A35, 37A50, 68U99

description: We describe the fundamental constructions and properties of determinantal probability measures and point processes, giving streamlined proofs. We illustrate these with some important examples. We pose several general questions and conjectures.
description: 26pp., Intl. Congress Math. 2014
title: Entre physiologie et chirurgie : Comment implémenter le peau-à-peau au bloc opératoire après une césarienne ?
title: Entre physiologie et chirurgie : Comment implémenter le peau-à-peau au bloc opératoire après une césarienne ?
titleType: AlternativeTitle
Creators: name: Beugin, Julie
name: Reyboubet, Ella
name: Wieland, Emily
Publisher: name: Unknown
Year: 0
Subjects: subject: Peau-à-peau immédiat
subject: Césarienne
subject: Implémentation
subject: Bloc opératoire
subject: Recommandations

description: Objectifs : L’objectif de cette revue de littérature est de pouvoir identifier les façons dont le peau-à-peau immédiat, après une césarienne, peut être implémenté au bloc opératoire. Méthodologie : Afin de réaliser la revue de littérature, plusieurs bases de données ont été utilisées : PubMed, CINHAL, PSYCHInfo, et MIDIRS. Neuf articles ont été retenues, de types qualitatifs ou mixte. Les études sélectionnées sont de niveau de preuves III ou IV. Résultats : Les résultats ont été analysés selon une grille adaptée aux études sélectionnées (cf. Annexes). Les résultats principaux ont étés détaillés dans le corps du travail. Discussion : L’analyse de résultats a permis la construction de recommandations, sous forme de neuf étapes nécessaires à l’implémentation du peau-à-peau au bloc opératoire suite à une césarienne. Conclusion : Des pistes afin de pouvoir intégrer les résultats à la pratique sont amenées. Les limites de cette étude ainsi que les recherches supplémentaires nécessaires sont décrites.
title: Grossesses issues d’une procréation médicalement assistée : quel vécu pour les femmes ?
title: Grossesses issues d’une procréation médicalement assistée : quel vécu pour les femmes ?
titleType: AlternativeTitle
Creators: name: Brischoux, Louise
name: Chovelon, Chloé
name: Dumarquez, Axelle
Publisher: name: Unknown
Year: 0
Subjects: subject: Femme enceinte
subject: Grossesse
subject: Procréation médicalement assistée
subject: Infertilité
subject: Vécu
subject: Besoins

description: Objectifs : De nos jours, les grossesses issues de procréation médicalement assistée sont en augmentation. L'objectif de ce travail de Bachelor est d'analyser le vécu des femmes ayant conçu suite à un traitement d'infertilité afin de mettre en avant leurs besoins et leurs attentes durant leur grossesse. Méthodologie : Cette revue de littérature comprend huit articles regroupant des études qualitatives et quantitatives se portant sur le vécu des femmes ayant conçu par procréation médicalement assistée. Ils ont été sélectionnés sur les quatre bases de données suivantes : Medline Pubmed, MIDIRS, PsycINFO et CINAHL. Résultats et conclusion : Cette revue de littérature met en avant que les femmes ayant une grossesse issue d'un traitement d'infertilité présentent un vécu influencé par leur parcours. Différents aspects tels que la qualité de vie, les relations sociales et la parentalité sont touchés par leur histoire de conception. Ces femmes sont principalement plus anxieuses. Elles ont davantage de difficultés à s'adapter à leur grossesse, elles ont des craintes concernant la pérennité de cette dernière et des préoccupations concernant la santé de leur enfant. Un sentiment d'ambivalence, se portant sur leur grossesse et le suivi standard dont elles bénéficient, peut se manifester. En sus, un besoin de reconnaissance, tant de la part de leur entourage que des professionnels, est mis en évidence chez ces femmes. Pour ces différentes raisons, il semble alors intéressant que les femmes ayant une grossesse suite à un traitement d'infertilité bénéficient d'un suivi qui soit centré sur elles avec une continuité dans les soins.
Anomalous Accretion Activity and the Spotted Nature of the DQ Tau Binary System
Creators: name: Bary, Jeffrey S.
name: Petersen, Michael S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the detection of an anomalous accretion flare in the tight eccentric pre-main-sequence binary system DQ Tau. In a multi-epoch survey consisting of randomly acquired low to moderate resolution near-infrared spectra obtained over a period of almost ten years, we detect a significant and simultaneous brightening of four standard accretion indicators (CaII infrared triplet, the Paschen and Brackett series HI lines, and HeI 1.083 um), on back-to-back nights (phase = 0.372, 0.433) with the flare increasing in strength as the system approached apastron (phase = 0.5). The mass accretion rate measured for the anomalous flare is nearly an order of magnitude stronger than the average quiescent rate. While previous observations established that frequent, periodic accretion flares phased with periastron passages occur in this system, these data provide evidence that orbitally-modulated accretion flares occur near apastron, when the stars make their closest approach to the circumbinary disk. The timing of the flare suggests that this outburst is due to interactions of the stellar cores (or the highly truncated circumstellar disks) with material in non-axisymmetric structures located at the inner edge of the circumbinary disk. We also explore the optical/infrared spectral type mismatch previously observed for T Tauri stars and successfully model the shape of the spectra from 0.8 to 1.0 um and the strengths of the TiO and FeH bands as manifestations of large cool spots on the surfaces of the stellar companions in DQ Tau. These findings illustrate that a complete model of near-infrared spectra of many T Tauri stars must include parameters for spot filling factors and temperatures.
description: Accepted to ApJ
Clinical and Histological Findings of Denture Stomatitis as Related to Intraoral Colonization Patterns of Candida albicans , Salivary Flow, and Dry Mouth: Role ofC. albicansin Saliva, Mucosal and Denture Surfaces in DS
Creators: name: Barrow, David
name: Barros, Silvana
name: Offenbacher, Steven
name: Gendreau, Linda
name: Loewy, Zvi G.
name: Mendoza, Luisito
name: Preisser, John
name: Curran, Alice
name: Altarawneh, Sandra
name: Bencharit, Sompop
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Multifactorial etiological factors contribute to denture stomatitis (DS), a type of oral candidiasis; however, unlike other oral candidiasis, DS can occur in a healthy person wearing a denture. In this study, we therefore attempt to explore the association between candida, denture, and mucosal tissue using 1) exfoliative cytology, 2) the candidal levels present in saliva, on mucosal tissues and on denture surfaces, and 3) the salivary flow rate and xerostomic symptoms.
title: Deuil périnatal suite à une interruption thérapeutique de grossesse : le rôle professionnel de la sage-femme
title: Deuil périnatal suite à une interruption thérapeutique de grossesse : le rôle professionnel de la sage-femme
titleType: AlternativeTitle
Creators: name: Corthésy, Léa
name: Plana Brell, Elisabet
name: Verdon, Sandrine
Publisher: name: Unknown
Year: 0
Subjects: subject: Interruption thérapeutique de la grossesse
subject: Accompagnement sage-femme
subject: Deuil périnatal

description: Objectif : Au travers du vécu des professionnels et des parents, ce travail de recherche vise à identifier dans quelle mesure le rôle sage-femme est-il aidant dans l’accompagnement psychologique des couples confrontés au deuil périnatal suite à une interruption thérapeutique de grossesse. Méthodologie : Une revue de littérature a été réalisée. Pour ce faire, nous avons effectué nos recherches sur différentes bases de données : PubMed, CINAHL, MIDIRS et PsycINFO. En tenant compte de nos critères d’inclusion et d'exclusion, huit études ont été retenues pour leur pertinence avec notre sujet de recherche. Nous disposons de quatre articles qualitatifs, trois articles quantitatifs et un article mixte. Chaque étude a fait l’objet d’une analyse détaillée. Résultats : Notre travail de recherche met en évidence les facteurs influençant le processus de deuil périnatal suite à une interruption thérapeutique de grossesse. Deux éléments prépondérants sont ressortis : le vécu des soignants et le vécu des parents. Pour les professionnels, le besoin de formation et de soutien est ressorti. Différents mécanismes et stratégies d’adaptation utilisés par les parents ont émergé. Conclusion : Cette revue de littérature met l’accent sur la complexité ainsi que sur l’importance du rôle sage-femme dans la prise en charge des couples endeuillés lors d’une interruption thérapeutique de grossesse. Elle donne également des pistes de prise en charge pour la pratique professionnelle afin d’offrir un accompagnement adéquat aux couples dans leur processus de deuil.
GFSWeb:  A Web Tool for Genome-Based Identification of Proteins from Mass Spectrometric Samples
Creators: name: Holmes, Mark R.
name: Giddings, Morgan C.
name: Wisz, Michael S.
name: Suarez, Melissa Kimball
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: The interpretation of mass spectrometry data for protein identification has become a vital component of proteomics research. However, since most existing software tools rely on protein databases, their success is limited, especially as the pace of annotation efforts fails to keep pace with sequencing. We present a publicly available, web-based version of a software tool that maps peptide mass fingerprint data directly to their genomic origin, allowing for genome-based, annotation-independent protein identification.
INTERESSE PUBBLICO E FORMA SOCIETARIA
Creators: name: ORSONI, CATERINA
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: At the end of the privatization process - implemented since the 90s -, the economic participation of the Italian public powers is, today, almost exclusively explicated through common law companies, operating in the market such as private parties. However, the rules that govern these companies entail a lot of exceptions to the provisions normally applied for the same private entities, and this situation implies that the juridical nature of such companies is actually extremely complex.
Fermionic and Majorana Bound States in Hybrid Nanowires with Non-Uniform Spin-Orbit Interaction
Creators: name: Klinovaja, Jelena
name: Loss, Daniel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study intragap bound states in the topological phase of a Rashba nanowire in the presence of a magnetic field and with non-uniform spin orbit interaction (SOI) and proximity-induced superconductivity gap. We show that fermionic bound states (FBS) can emerge inside the proximity gap. They are localized at the junction between two wire sections characterized by different directions of the SOI vectors, and they coexist with Majorana bound states (MBS) localized at the nanowire ends. The energy of the FBS is determined by the angle between the SOI vectors and the lengthscale over which the SOI changes compared to the Fermi wavelength and the localization length. We also consider double-junctions and show that the two emerging FBSs can hybridize and form a double quantum dot-like structure inside the gap. We find explicit analytical solutions of the bound states and their energies for certain parameter regimes such as weak and strong SOI. The analytical results are confirmed and complemented by an independent numerical tight-binding model approach. Such FBS can act as quasiparticle traps and thus can have implications for topological quantum computing schemes based on braiding MBSs.
title: Le contenu optimal d'une application smartphone promouvant l'activité physique chez les étudiants du niveau tertiaire
title: Le contenu optimal d'une application smartphone promouvant l'activité physique chez les étudiants du niveau tertiaire
titleType: AlternativeTitle
Creators: name: Minnig, Maëlle
name: Rohrbach, Eloïse
Publisher: name: Unknown
Year: 0
Subjects: subject: Activité physique
subject: Etudiant
subject: Universitaire
subject: Haute Ecole
subject: Application
subject: Internet
subject: Smartphone

description: Introduction : Les études supérieures sont associées à un fort risque d’inactivité physique. Pourtant la pratique d’exercice compte de nombreux bienfaits qui sont profitables aux étudiants. L’utilisation de la technologie pour encourager l’activité physique (AP) semble très appropriée pour cette population et a déjà démontré son efficacité. L’objectif de cette revue est de définir le contenu optimal d’une application smartphone afin de promouvoir l’AP auprès des étudiants du niveau tertiaire. Méthode : Une recherche d’articles a été effectuée, entre septembre 2016 et février 2017, dans les bases de données CINHAL, Embase et Pubmed Medline. Les critères d’inclusions étaient : une population universitaire aux moeurs occidentales, l’AP comme outcome principal mesuré par l’IPAQ, une intervention par application ou site internet. Six articles ont été sélectionnés puis évalués à l’aide de la grille McMaster. Résultats : Cinq études ont obtenu un effet sur la pratique d’AP des universitaires. Les fonctionnalités qui tendent à avoir un meilleur impact sont : la fixation d’objectifs, la planification de l’AP, des cours en ligne ainsi que la transmission d’encouragements et de feedbacks par un coach ou par courriels. L’application doit également tenir compte de l’environnement de l’utilisateur, de ses capacités d’autorégulation et du maintien de sa motivation. De plus, le logiciel doit être spécifique à l’AP. Conclusion : Cette revue a permis de mettre en évidence certaines recommandations concernant le contenu du logiciel. Néanmoins, des recherches supplémentaires sont nécessaires afin de confirmer les résultats obtenus et définir les stratégies à adopter pour maintenir l’effet sur le long terme.
On the Mechanism of the Volume Reflection of Relativistic Particles
Creators: name: Kovalev, Gennady V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The mechanisms of the volume reflection of positively and negatively charged relativistic particles in a bent crystal have been analyzed. It has been shown that the empty core effect is significant for the negatively charged particles. The average reflection angle of the negatively charged particles has been determined and the conditions for the observation of the reflection and refraction are discussed.
description: 4 pages, 2 figures
Pathway Biomarker Profiling of Localized and Metastatic Human Prostate Cancer Reveal Metastatic and Prognostic Signatures †
Creators: name: Mohler, James L.
name: Deng, Jianghong
name: Rubin, Mark
name: Liotta, Lance A.
name: Linehan, W. Marston
name: Pinto, Peter A.
name: Grubb, Robert L.
name: Petricoin, Emanuel F.
name: Wulfkuhle, Julia D.
name: Chinnaiyan, Arul
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Reverse phase protein microarray technology was used to study key signaling pathways thought to be involved in the progression of benign epithelium to the lethal phenotype of prostate cancer. Specimens of androgen-stimulated localized prostate cancer (N=21) and androgen-deprivation therapy-recurrent local (N=4) or metastatic (N=11) prostate cancer were laser capture microdissected prior to analysis. The results showed significant increases in protein expression levels in malignant epithelial cells and patient-matched stromal tissue, which included higher levels of the apoptotic proteins Bax and Smac/Diablo and increased phosphorylation of Bcl2 (S70). The mitochondrial protein Smac/Diablo and the transcription regulatory protein STAT3 (Y705) correlated with Gleason sum and differed statistically in high Gleason grade (8-10) prostate cancers. Distinct metastasis-specific pathways were activated by caspase cleavage activation, ErbB2 phosphorylation, Bax total protein and Bcl-2 phosphorylation while phosphorylation of all three members of the MAPK family, ERK, p38 and SAP/JNK, were reduced significantly in metastatic lesions compared to primary cancers. This study, the most comprehensive pathway analysis ever performed for human prostate cancer, presents evidence of specific pathway biomarkers that may be useful for assessment of prognosis and stratification for therapy if validated in larger clinical study sets.
Streamline Proteomic Approach for Characterizing Protein−Protein Interaction Network in a RAD52 Protein Complex
Creators: name: Chen, Xian
name: Shen, Zhiyuan
name: Du, Yuchun
name: Fan, Jinjiang
name: Zhou, Jianhong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Large-scale identification of protein-protein interactions (PPIs) in functional complexes represents an efficient route to elucidate the regulatory rules of cellular functions. While many methods have been developed to identify the PPIs associated with particular target/bait protein in complexes, little information is available about the interaction relationships among all components in a complex. Here, we have established a strategy of integrating proteomic identification of complex components with mammalian two-hybrid screening of their binary relationships to achieve information content of both breadth (i.e., identifying all potential interacting partners of the protein of interest) and depth (i.e., detailed mapping of the physical interactions of a subset of the identified and functionally related proteins) in characterizing protein complexes. In the initial phase of quantitative proteomic analysis of this streamline, the proteins that specifically complex with the target/bait protein were pulled down by immunoprecipitation and identified by mass spectrometry (MS)-based “dual-tagging” quantitative proteomic approach. In the second phase of in-depth characterizations of binary relationships, the physical interactions of a subset of functionally closely related complex components are mapped by mammalian two-hybrid assay. The screening for binary relationships of complex components not only serves as a validation of the first phase of proteomic identification, but also further deepens the understanding of the protein complex of interest. With this streamlined approach, we studied the protein complexes that are associated with a DNA recombination protein RAD52. In the initial phase, multiple proteins both known and unknown to interact with RAD52 were identified by the “dual-tagging” proteomic method. In the second phase, a complex protein-protein interaction network, which may play important roles in coordinating the activity of DNA repair with that of cell division, was defined by the mammalian two-hybrid assay.
title: Accompagnement infirmier des nouveaux résidents en perspective d’une demande d’assistance au suicide.
title: Accompagnement infirmier des nouveaux résidents en perspective d’une demande d’assistance au suicide.
titleType: AlternativeTitle
Creators: name: Bolaños Bonilla, Veronica Marcela.
Publisher: name: Unknown
Year: 0
Subjects: subject: Assistance au suicide
subject: Personne âgée
subject: EMS
subject: Transition
subject: Rôle infirmier

description: Introduction : L’assistance au suicide est une pratique tolérée en Suisse sous certaines conditions. Le nombre de demandes est en constante augmentation depuis ces dernières années notamment dans le contexte des EMS. Objectif : Identifier l’accompagnement infirmier pour les nouveaux résidents qui font une demande d’assistance au suicide. Méthode : Les bases de données CINAHL et PubMed ont été explorées afin de sélectionner sept articles de recherches provenant d’Australie, d’Irlande, de la Belgique, de Norvège et des Pays-Bas. Ceux-ci ont été analysés et synthétisés afin d’en extraire les résultats en lien avec la question de recherche et le modèle de Meleis. Résultat : Aucun des sept articles sélectionnés pour ce travail ne donnent de réponse concrète à la question de recherche mais leur analyse permet d’identifier des points clés significatifs qui permettent de répondre au questionnement d’une manière très large. Conclusion : L’utilisation de la théorie de transitions de Meleis comme cadre théorique a permis d’analyser les résultats des articles scientifiques et ainsi identifier le rôle infirmière dans ces deux processus. Ainsi il a été de prodiguer des soins centrés sur la personne ayant une approche holistique. Concernant l’assistance au suicide l’infirmière est encouragée à prodiguer un accompagnement et un soutient aux patients et aux familles, ceci sans jugement.
Probing the presence of planets in transition discs' cavities via warps: the case of TW Hya
Creators: name: Facchini, Stefano
name: Ricci, Luca
name: Lodato, Giuseppe
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We are entering the era in which observations of protoplanetary discs properties can indirectly probe the presence of massive planets or low mass stellar companions interacting with the disc. In particular, the detection of warped discs can provide important clues to the properties of the star-disc system. In this paper we show how observations of warped discs can be used to infer the dynamical properties of the systems. We concentrate on circumbinary discs, where the mass of the secondary can be planetary. First, we provide some simple relations that link the amplitude of the warp in the linear regime to the parameters of the system. Secondly, we apply our method to the case of TW Hya, a transition disc for which a warp has been proposed based on spectroscopic observations. Assuming values for the disc and stellar parameters from observations, we conclude that, in order for a warp induced by a planetary companion to be detectable, the planet mass should be large ($M_{\rm p} \approx 10 - 14M_{\rm J}$) and the disc should be viscous ($α\approx 0.15 - 0.25$). We also apply our model to LkCa 15 and T Cha, where a substellar companion has been detected within the central cavity of the transition discs.
description: 12 pages, 4 figures, 2 tables. Accepted for publication in MNRAS
Proteomic Dissection of Cell Type-Specific H2AX-Interacting Protein Complex Associated with Hepatocellular Carcinoma
Creators: name: Du, Ruyun
name: Yao, Jun
name: Long, Jing
name: Bao, Huimin
name: Chen, Xian
name: Yang, Xiaoli
name: Yun, Dong
name: Zou, Peng
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The replacement histone variant H2AX senses DNA double-strand breaks (DSBs) and recruits characteristic sets of proteins at its phosphorylated (γ-H2AX) foci for concurrent DNA repair. We reasoned that the H2AX interaction network, or interactome formed in the tumor-associated DNA DSB environment such as in hepatocellular carcinoma (HCC) cells, where pre-neoplastic lesions frequently occur, is indicative of HCC pathogenic status. By using an in vivo dual-tagging quantitative proteomic method, we identified 102 H2AX-specific interacting partners in HCC cells that stably expressed FLAG-tagged H2AX at close to the endogenous level. Using bioinformatics tools for data-dependent network analysis, we further found binary relationships among these interactors in defined pathway modules, implicating H2AX in a multi-functional role of coordinating a variety of biological pathways involved in DNA damage recognition and DNA repair, apoptosis, nucleic acid metabolism, Ca2+-binding signaling, cell cycle, etc. Furthermore our observations suggest that these pathways interconnect through key pathway components or H2AX interactors. The physiological accuracy of our quantitative proteomic approach in determining H2AX-specific interactors was evaluated by both co-immunoprecipitation/ immunoblotting and confocal co-localization experiments performed on HCC cells. Due to their involvement in diverse functions, the H2AX interactors involved in different pathway modules, such as Poly(ADP-ribose) polymerase1, 14-3-3ζ, coflin1, and peflin1, were examined for their relative H2AX binding affinities in paired hepatocytes and HCC cells. Treatment with the DSB-inducing agent bleomycin enhanced binding of these proteins to H2AX, suggesting an active role of H2AX in coordinating the functional pathways of each protein in DNA damage recognition and repair.
Meta-analysis of shape bias
Creators: name: Abdelrahim, Samah
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Social and Behavioral Sciences
subject: Developmental Psychology
subject: Psychology
subject: FOS: Psychology

description: Research title Evaluating the evidence of shape bias in children cross-culturally: a meta-analysis Rationale How children acquire the meanings of words has been a lingering question for psycholinguists for a long time, and some researchers made proposals about the approach children could possibly be taking to acquire meanings rapidly. Some of those proposals are conceptual and perceptual biases and constraints that potentially facilitate this process, and one of them is "shape bias". The shape bias proposal states that children attend to the shape of objects more than any other attributes like color, texture, or material when mapping a newly learn word to a referent, in other words, when forming categories that govern generalization of words to new instances. (Landau et al., 1988) Since then, shape bias has been investigated by many researchers, in English and other languages. Over the course of more than twenty years, studies were done in the US, Japan, China, The amazon forest “Tsimane”, Yucatec Mayan, and other places, yielding findings that are sometimes consistent, but other times conflicting. (Barner et al., 2009; Cimpian & Markman, 2005; Imai & Gentner, 1997; Jara-Ettinger et al., 2022; Yoshida & Smith, 2003) There was a general consensus that English-speaking children display a shape bias while eastern language speakers like Japanese and Mandarin are less prone to attend to shape, which was attributed to their languages’ lack of marking for the ontological categorization of count and mass in its grammar. The same effect was observed in studies that incorporated the solidity of objects as a continuum of complex solid objects, simple solid objects, and substances, but this time the effect was only observed in simple solid objects for which English speakers manifested a shape bias, while Speakers of Mandarin and Japanese did not. Studies that were done with Tsimane’ group also displayed a similar pattern to Mandarin and Japanese speakers. However, the overall effect size of shape bias in all different languages, and environments, with all different types of exemplar objects is yet to be determined. All these studies use different types of stimuli, tasks, measures, and analyses. Some researchers interpret their results as being a product of syntactic differences, others refer to the lexical statistics of the language spoken, and some highlight the environmental differences and exposure to complex artifacts as an explanation. In light of all that, a meta-analysis of the literature on shape bias becomes necessary and beneficial on many levels. Objectives It is hoped that the result of this meta-analysis study will be a clearer and more precise overall estimate of the effect size of shape bias and a better comprehension of the reported cross-cultural differences, as well as the within and between studies differences.
14-3-3ε Boosts Bleomycin-induced DNA Damage Response by Inhibiting the Drug-resistant Activity of MVP
Creators: name: Tang, Siwei
name: Bai, Chen
name: Yang, Pengyuan
name: Chen, Xian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Major vault protein (MVP) is the predominant constituent of the vault particle, the largest known ribonuclear protein complex. Although emerging evidences have been establishing the links between MVP (vault) and multidrug resistance (MDR), little is known regarding exactly how the MDR activity of MVP is modulated during cellular response to drug-induced DNA damage (DDR). Bleomycin (BLM), an anti-cancer drug, induces DNA double-stranded breaks (DSBs) and consequently triggers the cellular DDR. Due to its physiological implications in hepatocellular carcinoma (HCC) and cell fate decision, 14-3-3ε was chosen as the pathway-specific bait protein to identify the critical target(s) responsible for HCC MDR. By using LC-MS/MS-based proteomic approach, MVP was first identified in the BLM-induced 14-3-3ε interactome formed in HCC cells. Biological characterization revealed that MVP possesses specific activity to promote the resistance to the BLM-induced DDR. On the other hand, 14-3-3ε enhances BLM-induced DDR by interacting with MVP. Mechanistic investigation further revealed that 14-3-3ε, in a phosphorylation-dependent manner, binds to the phosphorylated sites at both Thr52 and Ser864 of the monomer of MVP. Consequently, the phosphorylation-dependent binding between 14-3-3ε and MVP inhibits the drug-resistant activity of MVP for an enhanced DDR to BLM treatment. Our findings provide an insight into the mechanism underlying how the BLM-induced interaction between 14-3-3ε and MVP modulates MDR, implicating novel strategy to overcome the chemotherapeutic resistance through interfering specific protein-protein interactions.
PPE38 of Mycobacterium marinum Triggers the Cross-Talk of Multiple Pathways Involved in the Host Response, As Revealed by Subcellular Quantitative Proteomics
Creators: name: Dong, Dandan
name: Wang, Hui
name: Chen, Xian
name: Gao, Qian
name: Tang, Siwei
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The PE/PPE family of proteins which are in high abundance in pathogenic species such as Mycobacterium tuberculosis and M. marinum, play the critical role in generating antigenic variation and evasion of host immune responses. However, little is known about their functional roles in mycobacterial pathogenesis. Previously, we found that PPE38 is associated with the virulence of mycobacteria, presumably by modulating the host immune response. To clarify the link between PPE38 and host response, we employed a subcellular, amino acid-coded mass tagging (AACT)/SILAC-based quantitative proteomic approach to determine the proteome changes during host response to M. marinum PPE38. As a result, 291 or 290 proteins were found respectively to be up- or down-regulated in the nucleus. Meanwhile, 576 upregulated and 272 downregulated proteins were respectively detected in the cytosol. The data of quantitative proteomic changes and concurrent biological validations revealed that M. marinum PPE38 could trigger extensive inflammatory responses in macrophages, probably through interacting with toll-like receptor 2 (TLR2). We also found that PPE38 may arrest MHC-1 processing and presentation in infected macrophages. Using bioinformatics tools to analyze global changes in the host proteome, we obtained a PPE38-respondor network involved in various transcriptional factors (TFs) and TF-associated proteins. The results of our systems investigation now indicate that there is cross-talk involving a broad range of diverse biological pathways/processes that coordinate the host response to M. marinum PPE38.
Entre el realismo y lo fantástico: Una aproximación a la narrativa de Selva Almada, María Gainza, Samanta Schweblin y Mariana Enríquez. Parte II
Creators: name: Muñoz Sánchez, Juan Ramón
Publisher: name: Artifara
Year: 2022

description: El presente estudio pretende analizar la propuesta literaria de cuatro de las autoras más representativas de lo que se ha denominado la nueva narrativa argentina, Selva Almada (Villa Elisa, Entre Ríos, 1973), María Gainza (Buenos Aires, 1975), Samanta Schweblin (Buenos Aires, 1978) y Mariana Enríquez (Buenos Aires, 1973), a partir de cuatro obras paradigmáticas de cada una de ellas, Ladrilleros (2013), El nervio óptico (2014), Distancia de rescate (2014) y Nuestra parte de noche (2019). Se trata de cuatro universos referenciales muy distintos entre sí, aunque están traspasados por determinados temas y cuestiones comunes. El artículo se presenta dividido en dos partes; la primera, además de la introducción, contiene los análisis de Ladrilleros, de Selva Almada, y El nervio óptico, de María Gainza, y la bibliografía citada. La segunda parte estará integrada por los estudios de Distancia de rescate, de Samanta Schweblin, y Nuestra parte de noche, de Mariana Enríquez, por la conclusión y por toda la bibliografía empleada.
description: Artifara, N. 22.2 (2022)
Diagnostic Profiles and Clinical Characteristics of Youth Referred to a Pediatric Mood Disorders Clinic
Creators: name: WALSHAW, PATRICIA D.
name: FORGEY-BORLICK, MARCY J.
name: MARC, J.
name: PODELL, JENNIFER L.
name: MIKLOWITZ, DAVID J.
name: KIM, EUNICE Y.
name: SUDDATH, ROBERT L.
name: YOUNGSTROM, WEINTRAUB ERIC A.
name: MATKEVICH, BRITTANY N.
name: MARVIN, SARAH E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The current study examined the diagnostic profiles and clinical characteristics of youth (ages 6–18) referred for diagnostic evaluation to a pediatric mood disorders clinic that specialized in early-onset bipolar disorder.
Hidden architectures. History and drawing of “Unseen” towers in the province of Salerno
Creators: name: Morena, Sara
Publisher: name: Universita degli studi di Salerno
Year: 2018
Subjects: subject: ICAR/17 DISEGNO
subject: Cultural heritage
subject: Photogrammetry
subject: Multidisciplinary

description: 2016 - 2017
description: The interest in the protection and conservation of Cultural Heritage and the growing role that it plays in the development ofthe national policies, represents a valid reason to focus the attention ofthe research in this lield and transmitting the uniqueness and the identity of own territory is a lirst and fundamental step to guarantee its sustainability. Above all, in an era of globalization, cultural heritage helps us to remember our history and diversity, and its understanding develops the respect and the dialogue amongst different cultures. However, despite our nation preserves lesser-known architectures of great value, often it pours into a state of abandonment and, in some case, is not even notorious by the majority of the community. The technological diffusion and the great improvement of digitalization, could positively contribute to broadening the tools of knowledge and favouring greater disclosure and accessibility. Hence, the purpose of my PhD doctoral thesis consists in the development of an innovative methodology of protection and conservation of architectural heritage. Through a multidisciplinary approach, that inextricably links the history and new technology in the field of surveying, the aim is the identification of originai systems of cataloguing and archiving of data, useful for the interpretation of the built, as well as the generation of infographics models to analyse, preserve and divulge... [edited by Author]
The hunt for red AGN: a new infrared diagnostic
Creators: name: Fadda, Dario
name: Rodighiero, Giulia
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We introduce a new infrared diagnostic to separate galaxies on the basis of their dominant infrared emission: stellar or nuclear. The main novelty with respect to existing diagnostics, is the usage of a broad band encompassing at the same time the 9.7micron Silicate absorption feature and one of the adjacent broad PAH (polycyclic aromatic hydrocarbon) features. This provides a robust estimate of the near- to mid-infrared continuum slope and enables a clear distinction among different classes of galaxies up to a redshift z=2.5. The diagnostic can be applied to a wealth of archival data from the ISO, Spitzer, and Akari surveys as well as future JWST surveys. Based on data in the GOODS, Lockman Hole, and North Ecliptic Pole (NEP) fields, we find out that approximately 70% active galactic nuclei detected with X-ray and optical spectroscopy dominate the total mid-infrared emission. Finally, we estimate that AGN contribute less than 30% of the mid-infrared extragalactic integrated emission.
description: 5 pages, 4 figures, accepted for publication in MNRAS
Acceptance-based Behavior Therapy for Depression With Psychosis: Results From a Pilot Feasibility Randomized Controlled Trial
Creators: name: MILLER, IVAN W.
name: GAUDIANO, BRANDON A.
name: NOWLAN, KATHRYN
name: WENZE, SUSAN J.
name: EPSTEIN-LUBOW, GARY
name: BUSCH, ANDREW M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Acceptance-based depression and psychosis therapy (ADAPT), a mindfulness/acceptance-based behavioral activation treatment, showed clinically significant effects in the treatment of depression with psychosis in a previous open trial. The goal of the current study was to further test the feasibility of ADAPT to determine the utility of testing it in a future clinical trial, following a stage model of treatment development. Feasibility was determined by randomizing a small number of patients (N = 13) with comorbid depression and psychosis to medication treatment as usual plus enhanced assessment and monitoring (EAM) versus ADAPT for 4 months of outpatient treatment. Both conditions were deemed acceptable by patients. Differences in between-subjects effect sizes favored ADAPT post-treatment and were in the medium to large range for depression, psychosocial functioning, and experiential avoidance (ie, the target mechanism). Thus ADAPT shows promise for improving outcomes compared to medications alone and requires testing in a fully powered randomized trial.
$p$-torsion coefficient systems for ${\rm SL}_2({\bf Q}_p)$ and ${\rm GL}_2({\bf Q}_p)$,
Creators: name: Grosse-Klönne, Elmar
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We show that the categories of smooth ${\rm SL}_2({\mathbb Q}_p)$-representations (resp. ${\rm GL}_2({\mathbb Q}_p)$-representations) of level $1$ on $p$-torsion modules are equivalent with certain explicitly described equivariant coefficient systems on the Bruhat-Tits tree; the coefficient system assigned to a representation $V$ assigns to an edge $τ$ the invariants in $V$ under the pro-$p$-Iwahori subgroup corresponding to $τ$. The proof relies on computations of the group cohomology of a compact open subgroup group $N_0$ of the unipotent radical of a Borel subgroup.
A new approach to Poincaré-type inequalities on the Wiener space
Creators: name: Lanconelli, Alberto
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60H07, 60H30, 60H40

description: We prove a new type of Poincaré inequality on abstract Wiener spaces for a family of probability measures which are absolutely continuous with respect to the reference Gaussian measure. This class of probability measures is characterized by the strong positivity (a notion introduced by Nualart and Zakai in [17]) of their Radon-Nikodym densities. Measures of this type do not belong in general to the class of log-concave measures, which are a wide class of measures satisfying the Poincaré inequality (Brascamp and Lieb [2]). Our approach is based on a point-wise identity relating Wick and ordinary products and on the notion of strong positivity which is connected to the non negativity of Wick powers. Our technique leads also to a partial generalization of the Houdré and Kagan [8] and Houdr?é and P?érez-Abreu [9] Poincaré-type inequalities.
description: 15 pages
Spatial and Temporal Evolution of Particle Migration in Gap-Graded Granular Soils: Insights from Experimental Observations
Creators: name: Annapareddy, V. S. Ramakrishna
name: Sufian, Adnan
name: Bore, Thierry
name: Scheuermann, Alexander
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: This study presents physical observations and insights into particle migration characteristics throughout the suffusion process. Using a purpose-built coaxial permeameter cell, suffusion experiments were conducted on idealised internally unstable gap-graded granular soils at varying fines content and hydraulic loading conditions. The specimens were prepared with a mixture layer comprising finer and coarser fractions underlying a coarse layer composed of the coarser fraction alone. This enabled the finer fraction within the mixture layer to migrate through the coarse layer with upward seepage flow. The local porosity profile along the specimen was determined using spatial time domain reflectometry and an inversion algorithm, which enabled the development of a novel field map of the difference in porosity from the initial condition. This field map provided a visual guide of the spatial and temporal variation in porosity and enabled particle migration internally within the specimen to be quantitatively characterised from onset to progression to washout. The limiting onset condition identified from the field map was shown to be comparable to that obtained using conventional approaches, thereby providing strong validation for the application of porosity-based field maps. As suffusion progressed, the height of infiltrating finer particles into the coarse layer increased linearly with time, while the overall rate of particle migration from the mixture layer to the coarse layer evolved in a non-linear manner with the rate of migration increasing as the specimen reached a complete mixture condition, where the finer fraction infiltrated the entire coarse layer. The attainment of a complete mixture condition was dependent on the fabric of the gap-graded soil ... (see PDF for full abstract).
description: 28 pages, 20 figures. Article published in Journal of Geotechnical and Geoenvironmental Engineering 2023 (see https://ascelibrary.org/doi/10.1061/JGGEFK.GTENG-11094)
Temperament and character traits in patients with bipolar disorder and associations with comorbid alcoholism or anxiety disorders
Creators: name: Glahn, David C.
name: Robert Cloninger, C.
name: Bowden, Charles L.
name: Hatch, John P.
name: Serap Monkul, E.
name: Najt, Pablo
name: Nicoletti, Mark A.
name: Nery, Fabiano G.
name: Soares, Jair C.
name: Fonseca, Manoela
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Temperament and character traits may determine differences in clinical presentations and outcome of bipolar disorder. We compared personality traits in bipolar patients and healthy individuals using the Temperament and Character Inventory (TCI) and sought to verify whether comorbidity with alcoholism or anxiety disorders is associated with specific personality traits. Seventy three DSM-IV bipolar patients were compared to 63 healthy individuals using the TCI. In a second step, the bipolar sample was subgrouped according to the presence of psychiatric comorbidity (alcoholism, n = 10; anxiety disorders; n = 23; alcoholism plus anxiety disorders, n = 21; no comorbidity, n = 19). Bipolar patients scored statistically higher than the healthy individuals on novelty seeking, harm avoidance and self-transcendence and lower on self-directedness and cooperativeness. Bipolar patients with only comorbid alcoholism scored statistically lower than bipolar patients without any comorbidity on persistence. Bipolar patients with only comorbid anxiety disorders scored statistically higher on harm avoidance and lower on self-directedness than bipolar patients without any comorbidity. Limitations of this study include the cross-sectional design and the small sample size, specifically in the analysis of the subgroups. However, our results suggest that bipolar patients exhibit a different personality structure than healthy individuals and that presence of psychiatric comorbidity in bipolar disorder is associated with specific personality traits. These findings suggest that personality, at least to some extent, mediates the comorbidity phenomena in bipolar disorder.
A replication study on Lillard's Comparison of Classic Montessori, Supplemented Montessori Education, and Conventional Preschools
Creators: name: Narod Dabanyan
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Education
subject: Montessori

description: In her 2012 article, Lillard argues that Classic Montessori schools yield more positive outcomes in executive functions, establishment of word-picture relationship, and letter word identification. She also shows the benefits of Montessori education in mathematics and social relationships back in 2006. Despite being designed more than 100 years ago, Montessori education seems to yield concrete outcomes without up to date supplemental pedagogical materials. On the contrary, Lillard asserts that these supplemental materials dilute the positive outcomes of Montessori education and Montessori schools should rather stay loyal to Montessori's principles. This study aims to test the replicability of Lillard's findings from 2012.