cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Innovation as Capability and Freedom: Charting a Course of TRIPS Patent Protection in a Fair and Balanced Global Innovation System
Creators: name: Yu, Sa
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: TRIPS Agreement
Patent
Innovation
Development

description: This research aims to substantiate the idea that innovation is a capability that can be cultivated for equitable development and that a user’s freedom to innovate should not be violated by excessive intellectual property rights. The central feature of this idea is the principle of substantive equality of innovation capability, which is comprised of five components: equality of innovation opportunity, neutrality of innovation models, accessibility of the innovation commons, dignity of the entrepreneurial spirit, and respect for indigenous innovation. These five components will ensure that everyone has the basic innovation capability to function in the knowledge society and a real opportunity to access the innovation commons, mix her intellect with raw innovation resources, and participate in the decision-making process that affects her innovation capability and freedom. This thesis envisions a fair and balanced global innovation system and proposes a two-pronged approach to incorporate the TRIPS patent regime into this system. To promote multi-dimensional and equitable development, an innovation capability approach to development aims to maximize the contribution of intellectual resources to economic growth and human development through cultivating innovation capability and harnessing the power of non-proprietary innovation models. To increase the effectiveness of innovation systems and promote democratic innovation governance, an innovation equality and freedom approach to the TRIPS patent regime advances distributive justice and intergenerational equality objectives of the global innovation regime. A fair and balanced global innovation system has legal implications for both national governments and international institutions. A national government has the obligation to bring each and every citizen to a point of fair competition in the innovation market. This means that the government should provide equal opportunity to freely access the innovation commons and equally participate in the decision-making process that affects each person’s innovation capability and freedom. In addition, an optimal system of innovation ought to be based on a complementary combination of proprietary and non-proprietary systems in order to produce the highest attainable rates of innovation, productivity, and social utility. For international institutions, I suggest that the WIPO may be a more appropriate forum than the WTO for global innovation governance.
Names, Travelers, Transindividuality: Italo Calvino in the 1970s
Creators: name: Ovan, Sabrina
Publisher: name: Università degli Studi di Milano
Year: 2012

description: Situating the novel within the cultural, literary and political milieu of the period, this article provides a reading of Italo Calvino‟s 1979 hypernovel If on a Winter’s Night a Traveler and its relation to the French literary group Oulipo. It analyzes the work‟s link to questions of authorship and collectivity at the core of 1970s literary, philosophical, and political discourse both in Italy and France. In particular, the analysis concentrates on the function of names in the novel as signifiers of individuality and/or collectivity
description: ENTHYMEMA, N° 7 (2012)
title: Dynamic Computed Tomography Angiography Perfusion for Stroke Treatment Selection
Creators: name: Sheronick, Raneem
Publisher: name: Graduate Studies
Year: 2025
Subjects: subject: Biophysics--Medical
subject: Artificial Intelligence

description: Acute Ischemic stroke (AIS) is a medical emergency that occurs due to a blockage of blood flow to the brain. For every minute a stroke is left untreated, approximately 1.9 million neurons die, emphasizing the need for rapid, accurate, and accessible diagnosis and treatment. The success of recanalization therapies relies on the imaging-based assessment of the extent and severity of tissue damage caused by the stroke. Computed tomography perfusion (CTP) imaging is the current imaging standard in AIS due to its ability to produce volumetric estimates of the ischemic core and penumbra and predict follow-up infarction to inform treatment decision-making. Dynamic CT angiography (dCTA) is a potential alternative to CT perfusion (CTP) for estimating infarct volumes and guiding EVT treatment decisions. dCTA offers several advantages, including rapid acquisition, minimal added radiation exposure, reduced susceptibility to motion artifacts, and ease of implementation on standard CT scanners without the need for specialized personnel. This thesis explores the use of dynamic CT angiography (dCTA) for estimating infarct core and penumbra volumes and predicting tissue outcome in acute ischemic stroke patients. Using a combination of traditional machine learning, deep learning, and statistical analyses, the feasibility of using dCTA as a reliable alternative to CTP in stroke imaging is determined. First, dCTA estimates of core and penumbra were produced using a voxel-wise machine learning model trained on dCTA-derived feature maps. Treatment eligibility was assessed based on target mismatch and large core criteria, using dCTA-derived volumes, and compared against CTP thresholds. In the large core group, dCTA demonstrated a sensitivity of 88% and specificity of 83%, while for target mismatch criteria, sensitivity and specificity were 78% and 88%, respectively. The results demonstrated that dCTA is comparable to CTP in identifying treatment eligible patients. However, agreement could improve with the use of more advanced predictive models. Second, a spatiotemporal deep learning architecture was applied to predict tissue outcomes from raw dCTA image sequences, with predicted volumes subsequently used to predict functional independence. The model predicted that infarct volumes achieved a Dice Similarity Coefficient of 0.41 and a mean volume error of 7.01 mL compared to ground truth lesion volumes measured on 24-hour DWI. Moreover, predicted lesion volumes showed a significant association with 90-day functional independence. Overall, the results demonstrated that dCTA can provide perfusion information and predict infarct volumes comparable to CTP, highlighting the potential of dCTA predictive models to enhance stroke treatment selection and clinical care.
Poverty Porn in Nineteenth-Century Fiction: Spectacle, Space, Surveillance, and the Victorian Imagination
Creators: name: WENMAN-JAMES, GARTH MICHAEL
Publisher: name: University of Surrey
Year: 2022

description: This thesis interrogates the Victorian slum novel and examines the ways in which
description: poverty is deployed to mediate desire. I describe this phenomenon as ‘poverty porn’.
description: Through an interdisciplinary analysis into the themes of spectacle, space, and
description: surveillance in the Victorian slum novel, this thesis considers the socio-cultural
description: implications of literary poverty porn and proposes that it functions as an extension of
description: slumming practices in which the richer classes entered impoverished areas as a leisure
description: pursuit. In identifying this relationship between the novel and slumming, I challenge the
description: apparently charitable intentions of nineteenth-century slum novelists. In ‘Chapter 1:
description: Spectacle’, I illustrate how Charles Dickens’s Oliver Twist (1837) and Margaret
description: Harkness’s In Darkest London (1889) present images that simultaneously evoke
description: sympathy for the poor while providing pleasure and entertainment for their readerships.
description: ‘Chapter 2: Space’ considers the ways in which Arthur Morrison’s Tales of Mean
description: Streets (1894) and Israel Zangwill’s Children of the Ghetto (1892) engage with spatial
description: relations in their representations of the slums, and critiques how each author constructs
description: slum spaces to articulate their own identities and beliefs. ‘Chapter 3: Surveillance’
description: discusses how Vernon Lee’s Miss Brown (1884) and Mary Elizabeth
description: Braddon’s Mary (1916) critique male philanthropic and artistic gazes and emphasise the
description: oppression of poor and working-class women under surveillance. In doing so, they reveal
description: poor women’s potential to enact social reform when they break away from the
description: scrutinising male gaze. Throughout these chapters, I explore how these texts are
description: informed by slumming practices and how they aim to produce various forms of pleasure
description: in their readerships. In doing so, this thesis also contextualises the slum novel in wider
description: nineteenth-century culture, uncovering relationships between poverty porn and
description: philanthropy, social class, gender, sexuality, immigration, identity, oppression, and
description: repression. This thesis thus offers new readings of both well-known and underdiscussed
description: slum novels while unearthing the implications of the various forms of poverty porn that
description: gripped the Victorian imaginary.
Just a Click Away: Radicalization in the Net Generation
Creators: name: Barfuss, Frank
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Radicalization
Far-Right Externism
Internet
Skinheads

description: The use of the Internet as vehicle of socialization has exploded in the 21st century and while this presents exciting possibilities, it also comes with troubling ones. Among those who have embraced this new medium are extremist groups, who use the Web as a space in which to communicate, exchange ideas, network and reach new followers. In regards to this last point, it provides them near unlimited opportunities to gain access to potential recruits and converts, raising interesting questions in terms of the dynamics of the radicalization process and how it manifests itself within the confines of this new arena. Through an analysis of postings made to the discussion board of Stormfront.org, this research paper examines whether or not the radicalization process follows the same transformative pattern in the virtual world as has been described in some of the leading academic theories that address this phenomenon in the physical one.
Spettri della violenza politica: gli anni Settanta in alcuni romanzi del nuovo millennio
Creators: name: Colleoni, Federica
Publisher: name: Università degli Studi di Milano
Year: 2012

description: La memoria della violenza politica in Italia resta divisa. Dal punto di vista degli studi sul trauma, si tratterebbe di un trauma collettivo che, non essendo stato elaborato, produce nella memoria collettiva una sorta di spettro, per utilizzare un termine usato da Freud e in seguito da Jacques Derrida nel suo Spectres de Marx (1993). L‘intervento si concentra sulla presenza spettrale della violenza politica in quattro romanzi italiani del nuovo millennio: Tuo figlio (2004) di Gian Mario Villalta, Il segreto (2003) di Geraldina Colotti, La Guerra di Nora (2003) di Antonella Tavassi La Greca, Il sogno cattivo (2006) di Francesca D‘Aloja.
description: ENTHYMEMA, N° 7 (2012)
Modulating the Catalytic Performance of an Immobilized Catalyst with Matrix Effects - A Critical Evaluation
Creators: name: Macro Man
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: 30601 Catalysis and Mechanisms of Reactions
subject: FOS: Chemical sciences
subject: 30301 Chemical Characterisation of Materials
subject: 30403 Characterisation of Biological Macromolecules
subject: 30402 Biomolecular Modelling and Design
subject: 30401 Biologically Active Molecules
subject: 30201 Bioinorganic Chemistry
subject: 30603 Colloid and Surface Chemistry
subject: 30399 Macromolecular and Materials Chemistry not elsewhere classified
subject: 30503 Organic Chemical Synthesis
subject: Organic Chemistry
subject: 30305 Polymerisation Mechanisms

description: catalysisModulating the Catalytic Performance of an Immobilized Catalystwith Matrix Effects - A Critical Evaluation
Theatre in the dark : dramaturgies of uncertainty.
Creators: name: Shyldkrot, Yaron
Publisher: name: University of Surrey
Year: 2020

description: This practice research inquiry examines the relationships between darkness and uncertainty in performance. ‘Theatre in the dark’, as the name suggests, refers to performances or events that physically locate the audience in the dark – either by using blindfolds or by positioning the audience in near/pitch darkness. Within the growing interest in darkness and obstructed vision in contemporary practices, this PhD – comprised of this thesis, practice presentations and contextualised documentation – explores the different dramaturgies and manifestations of uncertainty that are in play in these performances. Using Practice Research and embracing a compositional-structural perspective, I propose the framework of dramaturgies of uncertainty to analyse theatrical compositions that seek to challenge clarity and generate indeterminate and ambiguous perceptions, as a means to conceptualise the substantive role and possibilities of darkness in performance. At the same time, as uncertainty has been regarded as a prominent characteristic of the current socio-political climate this doctoral research suggests that while it may be overwhelming and alarming, uncertainty can also be a generative experience, producing different or new understandings of what is perceived. As theatre in the dark can equally influence and alter perception, darkness becomes a useful setting through which to investigate the broader ramifications of uncertainty and the possibilities it might generate. Therefore, this PhD argues that theatre in the dark can facilitate different modes of being with others that move beyond fixed visual recognition or identification. Through three cycles of exploration, which resulted in three performance presentations (Campfire (2016), Overcast (2017) and Certain Ways (2018)), I study how darkness evokes different perceptions and forms of engagement. As a result, and when contesting the dominance of the visual, this research seeks to outline an altered state of clarity, which can trouble different visual biases and regimes, and bring forward more plural and inclusive perceptions and views.
L’arcipelago postmoderno. Oreste del Buono e gli anni Settanta
Creators: name: Chiurato, Andrea
Publisher: name: Università degli Studi di Milano
Year: 2012

description: All‟interno della storiografia letteraria del secondo Novecento italiano la figura di Ore-ste del Buono è stata vittima di una singolare rimozione. Certo l‟impegno su diversi fronti – dal romanzo di genere al fumetto, dal costume alla critica letteraria – rende dif-ficile inquadrare un intellettuale dal «multilforme ingegno» (Paccagnini 108), tanto atipico rispetto ai canoni nostrani. Eppure è proprio tale eclettica varietà a costituire la spe-cificità di del Buono, a spingerci a riconoscere il suo principale ruolo sulla scena culturale, ovvero quello di mediatore. Mediatore tra codici e linguaggi, tra scuole di pensiero e movimenti, tra le ragioni del mercato e la costante ricerca della qualità… In quasi ogni aspetto della sua attività possiamo ritrovare tracce di un‟attitudine rara e preziosa insieme, specie durante gli anni Settanta.
Nel decennio precedente si erano diffusi nuovi, suggestivi slogan (morte dell‟autore, romanzo sperimentale…), destinati ad affascinare più di un appartenente alla futura ne-oavanguardia. Del Buono aveva seguito con interesse la querelle tra „antichi e novissimi‟, senza però cedere a facili entusiasmi. Traducendo buona parte dei nouveaux romanciers; indirizzando, in veste di consulente, alcune delle maggiori case editrici verso le mode e i paradigmi emergenti; e, soprattutto, reinventando il proprio stile di romanziere. Quest‟ultimo aspetto in particolare è stato trascurato dalla critica, più propensa a ricondurlo all‟area del neorealismo che a riconoscere la significativa evoluzione della sua prosa nel periodo successivo. Contrapponendo, al canto del cigno dell‟autore e alla parallela scomparsa del personaggio-uomo, la sua personalissima teoria di una «narrativa integrale» (del Buono, “Narrativa” 85). Del Buono si pone infatti in una posizione problemati-ca, defilata e poco propensa ad ogni forma di consorteria.
Il tentativo di cooptazione postuma tra le file dei simpatizzanti da parte del Gruppo 63 avrà breve fortuna (verrà incluso nella prima antologia del gruppo, ma non nelle se-guenti), e Renato Barilli arriverà addirittura a porlo a capo di un improbabile «Polo Bu-tor» (Chiurato 14), uno sparuto gruppo di „infiltrati‟ (insieme a Raffaele La Capria, Emilio Tadini, e Giuliano Gramigna) nelle file della compagine neoavanguardista. Quarant‟anni dopo la questione rimane aperta e l‟eredità di quel turbolento periodo è ancora oggetto di discussione. La nostra intenzione è proporre un approccio diverso, che cer-chi di restituire la fluidità e la ricchezza delle suggestioni di allora poi irrigiditesi in cate-gorie critiche spesso frutto di semplificazioni indebite. Del Buono, irriducibile outsider, ci permette così di riscoprire gli anni Settanta da un‟angolazione inedita e di colmare, nello stesso tempo, alcune improvvide lacune nella nostra memoria culturale
description: ENTHYMEMA, N° 7 (2012)
Empirical Protein Adsorption Model derived from the Biomolecular Adsorption Database
Creators: name: Solana, Gerardin
Publisher: name: Swinburne
Year: 2024

description: The study of protein adsorption on surfaces has been an area of exhaustive research. In the past 5 decades, much has been published in the way of empirical results from protein adsorption studies. The recent progress in biotechnology has resulted in an explosive growth in available bio-medical data from pharmaceutical studies, cancer therapy investigations, proteomics, genomics and protein adsorption studies (Han July 2002). Consequently, several projects and databases exist to cater for the large volume of available data - the Human Genome Project (Watson 1990), several Proteomic Databases and Software (Wojcik and Schächter 2000 ), Medical Science Databases – AIDSTRIALS, ANSTI, MIMS Online (Medical Sciences Databases), Protein-Protein Interaction Databases – PPID (Protein to Protein Interaction Database), The Mamallian Protein-Protein Database (The MIPS Mammalian Protein-Protein Interaction Database), Protein-Ligand interaction databases – PLD (Protein Ligand Database), to name a few. Existing databases concentrate on proteomics, protein-protein or protein-ligand interactions. This work presents the development and reimplementation of a protein-surface (protein adsorption) database – the Biomolecular Adsorption Database and the application of this database in the generation of an Empirical Protein Adsorption Model. Prior to this work, the Biomolecular Adsorption Database in existence comprised only of protein descriptors and a separate surface database was being developed(Nicolau Jr and Nicolau 2002). This research unifies and expands on these concepts by creating one comprehensive database comprising of protein, solution and surface information where researchers can compare their results, can see what kind of experiments have already been conducted and from which data mining and modelling can be performed. The work presents the development and re-implementation of the Biomolecular database to integrate improved features, the evaluation of its statistical quality and its application in the generation of an empirical piecewise model for protein adsorption. The database and empirical model presented in this thesis is expected to be of future value in developing a possible strategy for the engineering-style, design oriented prediction of protein adsorption using databases and empirical models.
Supplementary document for Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging - 5430128.pdf
Creators: name: Chen, Zhenghui
name: YU, WENTAO
name: Wong, Hei Man
name: Wong, Terence T. W.
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Supplementary document for Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging
Thermally Activated Stiffness Tuneable Lattice Structures
Creators: name: Mostofizadeh, Parham
Publisher: name: University of Surrey
Year: 2024
Subjects: Lattice Structures
Multi-material 3D Printing
Active Metamaterials

description: Lattice metamaterials, which consist of a combination of air and solid, exhibit favourable characteristics due to their significantly reduced weight in comparison to conventional bulk materials. With advancements in additive manufacturing techniques, the fabrication of these metamaterials in intricate geometries and diverse configurations has become achievable. A recent approach to broaden the range of design possibilities for these materials involves the use of multi-material additive manufacturing technology. This thesis investigates the elastic and inelastic mechanical properties of multi-material lattice structures through analytical, experimental, and finite element analyses. The objective is to comprehensively understand how the presence of different materials in various regions of a lattice material can impact its overall behaviour. The research aims to contribute to the development of high-performance, lightweight materials capable of adapting to environmental stimuli. To this end, 2D and 3D multi-material lattices were designed and fabricated using Polyjet 3D printing technology. The fabricated samples underwent a range of thermo-mechanical tests. First, various analytical models were developed for predicting the elastic behaviour of the lattices in order to investigate the impact of material variation and relative density. Subsequently, in order to understand the mechanical characteristics of the manufactured multi-material lattices beyond the elastic range, several thermo-mechanical studies were conducted. The studies examined how the temperature and strain rate dependence of individual materials affects the overall behaviour of the lattice in both the elastic and post-elastic domains. Ultimately, based on the previous thermo-mechanical investigations and in order to actively manipulate the mechanical characteristics of the structures, a cost-efficient conductive coating was developed and utilised on the polymeric lattice. The application of the coating allowed for precise adjustment of the mechanical properties of the multi-material lattice structures through Joule heating, hence facilitating the development of high-performance metamaterials with enhanced functionality and adaptability.
Figure S1. Statistics of the lungfish reference transcriptome and similarity among RNA-seq libraries.;Figure S2. Gene ontology enrichment analysis of genes upregulated in the lungfish 14 dpa tail blastema as compared to uninjured tail. ;Figure S3. In situ hybridization of sense-control probes for select genes upregulated in the 14 dpa lungfish tail blastema relative to uninjured tail tissue. from Salamander-like tail regeneration in the West African lungfish
Creators: name: Verissimo, Kellen Matos
name: Perez, Louise Neiva
name: Dragalzew, Aline Cutrim
name: Gayani Senevirathne
name: Darnet, Sylvain
name: Wainna Renata Barroso Mendes
name: Neves, Ciro Ariel Dos Santos
name: Santos, Erika Monteiro Dos
name: Moraes, Cassia Nazare De Sousa
name: Elewa, Ahmed
name: Shubin, Neil
name: Fröbisch, Nadia Belinda
name: Josane De Freitas Sousa
name: Schneider, Igor
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Developmental Biology

description: (a) Statistics or the lungfish reference transcriptome. (b) BUSCO assessment of transcriptome completeness. (c) Principal component analysis (PCA) of uninjured and 14 dpa lungfish tail libraries. (d) Spearman correlation matrix of uninjured and 14 dpa lungfish tail libraries.;(a) Biological process. (b) Cellular component. (c) Molecular function.;Scale bars of 1 mm (panoramic views) and 0.25 mm (enlarged view).
Depressive Symptomatology Following Interdisciplinary Palliative Rehabilitation: Mechanisms of Change and Longitudinal Course
Creators: name: Feldstain, Andrea
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2015
Subjects: Depression
Advanced cancer
Interdisciplinary intervention
palliative
rehabilitation
general self-efficacy

description: Patients with advanced cancer (PWAC) are living months-years longer. With advances in oncological care, their illness can be considered chronic rather than terminal. This population of survivors emerged within the last two decades and their needs are not well understood nor are appropriate resources available. A particular concern is depression. Both clinical and subclinical depressive symptomatology can impede functioning and quality of life (QOL). Using secondary clinical data from a palliative rehabilitation program (PRP), the thesis objectives were to a) examine pre-post changes in functioning and QOL, b) examine the mechanisms of change in depressive symptomatology, and c) examine the longitudinal course of depressive symptomatology. Study 1 examined pre-post changes in QOL and functioning. Outcomes from 67 PRP patients were analyzed using paired t-tests. Results revealed ameliorations in the majority of domains (e.g. physical functioning, malnutrition) including self-reported “depression.” These results counter the existing literature that has shown that these typically stay stable until one month before death, when they drastically worsen. This begins to support that rehabilitation may be beneficial for PWAC. Study 2 focused on the finding that depression scores decreased. Changes in systemic inflammation, exercise, and general self-efficacy (GSE) from 80 PRP patients were examined as predictors of change in depressive symptomatology using a hierarchical linear regression. The model accounted for 15% of change in depression symptomatology, and GSE was the only significant predictor. This suggests that a GSE theoretical framework may be helpful in reducing depressive symptomatology in interdisciplinary palliative rehabilitation. Study 3 focused on longitudinal depressive symptomatology. Three-month follow-up data from 80 patients were analyzed using a repeated measures ANOVA for continuous data and a Cochrane’s Q analysis for grouped data. Results revealed that patients maintained reduced scores at follow-up. This counters the existing literature, in which longitudinal maintenance is poor following exercise-based interventions. Therefore, PRP may offer something beyond what other published interventions have previously. These finding will be discussed in the context of other existing literatures and the implications will be discussed.
title: Calmodulin Regulation of Heart Disease Associated Striated Muscle Preferentially Expressed Protein Kinase (SPEG)
Creators: name: Steward, Joshua Tomlin
Publisher: name: Science
Year: 2025
Subjects: subject: SPEG
subject: CaM
subject: Protein Kinase
subject: Heart disease
subject: Biophysics
subject: Biochemistry

description: Heart diseases cause fourteen deaths per hour in Canada alone. Striated muscle Preferentially Expressed protein kinase (SPEG) is implicated in various heart diseases, muscle disorders, and progressive heart failure. Despite the potential clinical consequences of this protein, SPEG’s molecular structure, regulation, and kinase targets are largely uncharacterized. Calmodulin (CaM), a small protein that acts as a Ca2+ sensor in cells, regulates many proteins essential to muscle function, including SPEG. However, few studies investigate the regulation of SPEG’s two kinase domains, SPEG Kinase 1 (SK1) SPEG Kinase 2 (SK2), and none so far have used biochemical or structural methods to investigate CaM. Sensitive biophysical techniques like isothermal titration calorimetry (ITC) and valuable bioinformatic tools like AlphaFold3, a powerful structure prediction software, allowed us to identify and evaluate potential CaM-binding sites on SK1 and SK2. We determined that CaM binds to a C-terminal helix on both SK1 and SK2 with nM affinity which is comparable to other CaM activated kinases. Strikingly, SK1 and SK2 exhibit different binding modes: SK1 binds once (KD ≈ 0.48 × 10-6 M), while SK2 displayed two site binding with both nanomolar and micromolar affinities (KD ≈ 51.4 × 10-9 M and 9.62 × 10-6 M). This result was surprising, as CaM rarely displays two-site binding and previous papers had only hypothesized CaM regulation of SK1, not SK2. Moreover, when investigating the role of disease-associated mutations located at the predicted CaM-SPEG interface, specifically, R3248C, we discovered a near 30-fold decrease in CaM binding affinity to SK2. Based on a variety of constructs we created we predict that SK1 and SK2 cannot be expressed as individual domains in E. coli. These results provide necessary biochemical context for SPEG’s regulation by Ca2+ CaM, and insight into one potential for disease mechanism of R3248C, laying the foundation for future studies which, hopefully, may support therapeutic breakthroughs in treating heart diseases.
Proofs of Two Formulas of Vladeta Jovovic
Creators: name: Dhar, Aritram
Publisher: name: arXiv
Year: 2021
Subjects: subject: Combinatorics (math.CO)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 05A17, 05A19, 11P81, 11P82

description: In this paper, we first provide an analytic and a bijective proof of a formula stated by Vladeta Jovovic in the OEIS sequence A117989. We also provide a bijective proof of another interesting result stated by him on the same page concerning integer partitions with fixed differences between the largest and smallest parts.
description: 6 pages
OAM-based Electromagnetic Metasurfaces for mmWave and THz Wireless Communications
Creators: name: Ali, Ali
Publisher: name: University of Surrey
Year: 2023
Subjects: 5G-and-beyond networks
metasurfaces
millimetre wave (mmWave)
orbital angular momentum (OAM)
reflectarray antennas (RAs)
terahertz (THz)

description: Broadening the bandwidth, increasing the modulation level, and increasing spatial multiplexing order are potential pillars to improve the performance of wireless communication systems. Accordingly, this research proposes broadening the transmission bandwidth and employing spatial multiplexing to increase the capacity of future wireless networks. Resorting to high-spectrum resources has been suggested as an inevitable act to handle the flying demand on the internet to secure the needed bandwidth. Moreover, waves-carrying orbital angular momentum (OAM) have emerged as an additional degree of freedom in electromagnetic (EM) systems to promote higher data rates by exchanging several data streams over the same bandwidth. As obtaining practical solutions for future networks is of the main motives of this work, other technical aspects are carefully considered, such as cost, volume, weight, and ease of fabrication. Thus, low-profile and high-gain metasurfaces are employed to produce OAM waves with different modes, enable steerable OAM waves, and deliver OAM multiplexing. Reflectarray antennas and reflecting metasurfaces are used to generate helical waves by novel topologies at different frequencies. Various techniques are proposed to broaden the narrow bandwidth of periodic structures at the 5G millimetre wave (mmWave) and terahertz (THz) bands.

description:

description: The chief achievements of this research are reducing the feeder blockage effect of reflectarrays for the generated low-divergence high-gain OAM beams at 5G-mmWave frequencies, introducing the world's first technique to realize OAM multiplexing via a passive THz reflectarray illuminated by a single feeding source, and enabling the non-Line-of-Sight (NLoS) component of the high gain THz OAM beams and improving spectral efficiency through reflective metasurfaces. To this end, a MATLAB GUI tool is developed to acquire the required phase distribution of seamless phase variation. Promising results are obtained from the simulated and fabricated prototypes of different features and frequency ranges.
Uncaring Nurses: Violence in Academia
Creators: name: Berquist, Melissa Renee
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2017
Subjects: Violence
Power
Knowledge
Resistance
Differences
Nursing Academia

description: Workplace violence is an area of increasing concern worldwide. Issues of violence are well documented in nursing. To address this, a better understanding of the culture of nursing academia is required. Problems of incivility are reported between students, between students and faculty, and between faculty and faculty. The purpose of this study is to increase understanding of faculty to faculty violence in nursing academia. Guided by a theoretical framework incorporating the perspectives of Mason and Foucault and specifically on the concepts of violence, power, knowledge, difference and resistance, this study focuses on aspects of the social and cultural work environment, and organizational policies and procedures influencing workplace violence between faculty members. Using principles from critical ethnography, the research was conducted within three schools of nursing at universities in eastern Canada. Data collection included 29 semi-structured interviews with nursing faculty, key informants (including representation from management, human resources, support staff and human rights office) and mute document review. Three major themes emerged: the academic apparatus, experiencing academia, and coping mechanisms. Nursing academic culture is divergent, exhibiting fierce competitiveness and elitism, intertwined with pockets of support and resilience. Faculty identified diverse personal and professional strategies employed to withstand the challenges. Need for change was expressed by some faculty and managers. These findings may inform the efforts of faculty and management seeking transformation to a less competitive and elitist culture.
title: In-Situ Monitoring of Hydrogen Concentration Using Multimodal Sensor Fusion Enhanced by Machine Learning
Creators: name: Alcantara Costa, Marcos Ridiley
Publisher: name: Schulich School of Engineering
Year: 2025
Subjects: subject: Hydrogen
subject: Machine Learning
subject: Gas Sensing
subject: Ultrasonic
subject: Thermal Conductivity
subject: Engineering

description: Recent climatic changes, largely driven by escalating greenhouse gas concentrations, have compelled governments worldwide to seek solutions for emission reduction. Fossil fuels are the primary contributors to these emissions, intensifying the urgency for cleaner alternatives. Hydrogen, considered a sustainable energy source, is a notable contender. Nevertheless, this transition presents challenges due to hydrogen's distinct properties. Despite its promise, hydrogen poses flammability risks, exacerbated by its odorless and colorless nature. Additionally, its exceptional diffusivity not only increases the likelihood of leaks but also causes embrittlement in materials used to contain it. An important step toward achieving zero emissions is substituting natural gas supplied to households and industries with hydrogen. However, most existing pipelines are not suitable for transporting pure hydrogen. Thus, blending hydrogen with natural gas in current pipelines offers a way to significantly and immediately reduce greenhouse gas emissions. A major concern with this approach, however, is the potential for stratification within the mixture. Stratification can lead to segregation, increasing the risk of leaks, which are particularly hazardous given hydrogen’s high diffusivity and wider explosive limits. Additionally, the presence of hydrogen heightens the risk of embrittlement, potentially weakening the pipe structure. This study employs a novel sensing system that combines thermal conductivity and ultrasonic sensors to measure gas composition and ensure that hydrogen percentages remain within desired levels. These specific sensors were chosen because of hydrogen's distinct acoustic and thermal characteristics, which enhance measurement accuracy. To improve the accuracy of the results and fuse the multimodal data acquired by the multiple sensors, a machine learning model was developed for quantifying hydrogen concentration. The experimental setup consists of a sensing module equipped with ultrasonic and thermal conductivity sensors to measure hydrogen concentration. Furthermore, to account for operational factors that might influence sensor output, the sensing module is equipped with temperature, humidity, and pressure sensors. The outcome of this study is a real-time, affordable, and precise hydrogen concentration measurement system.
All Peoples’ Mission And The Legacy of J. S. Woodsworth: The Myth and the Reality
Creators: name: MacDonald, Eric
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Canadian History, 1867-1914
Social Gospel
James Shaver Woodsworth
Social Settlements
Winnipeg

description: The legacy of James Shaver Woodsworth, according to the traditional biographies, has been an indelible one on the Canadian historical landscape. His biographers have elevated Woodsworth to not only a hero of the Canadian political left, but of the whole nation. Studies of Woodsworth’s life have traditionally rested their case on All Peoples’ Mission in Winnipeg, calling it a watershed moment in the ideological development of J. S. Woodsworth. They characterize his time as Superintendent, from 1908-1913, as the defining moment which would later lead him to found the Cooperative Commonwealth Federation. This Master’s thesis seeks to analyze the historical periphery of this period in order to illustrate Woodsworth’s standard approach to the Social Gospel in Canada. By employing a micro-historical methodology, a greater context reveals that All Peoples’ Mission was not the dynamic, revolutionary institution that his biographers describe. Instead, Woodsworth spent his time in Winnipeg experimenting with different and sometimes conflicting philosophies. This stage of Woodsworth’s ideological development can instead be best characterized by his strong nativist beliefs. His writings and speeches during this period indicate a struggle between Woodsworth’s understanding of assimilation and integration. James Shaver Woodsworth was a far more complex character during this period than his biographers would have us believe.
Large N limit of Yang-Mills partition function and Wilson loops on compact surfaces
Creators: name: Dahlqvist, Antoine
name: Lemoine, Thibaut
Publisher: name: arXiv
Year: 2022
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We compute the Large N limit of several objects related to the two-dimensional Euclidean Yang-Mills measure on compact connected orientable surfaces of genus larger or equal to one, with a structure group taken among the classical groups of order N. Our result shows the convergence of all Wilson loops for all loops within a topological disc and all simple loops.
description: Minor update amending in particular a mistake in Theorem 3.1 regarding the partition function's limit in type D, zero genus case
Biomimetic Glycoside Hydrolysis by a Microgel Templated with a Competitive Glycosidase Inhibitor
Creators: name: Macro Man
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: 30601 Catalysis and Mechanisms of Reactions
subject: FOS: Chemical sciences
subject: 30603 Colloid and Surface Chemistry
subject: 30501 Free Radical Chemistry
subject: 30399 Macromolecular and Materials Chemistry not elsewhere classified
subject: Organic Chemistry
subject: 30305 Polymerisation Mechanisms
subject: 30306 Synthesis of Materials
subject: Supramolecular Chemistry

description: Biomimetic Glycoside Hydrolysis by a Microgel Templated with a Competitive Glycosidase Inhibitor
title: The Aural Stage: Radio Drama as Sonic Lazzi
Creators: name: Brewin, Jennifer Amea
Publisher: name: Graduate Studies
Year: 2025
Subjects: subject: Physical Theatre
subject: Site Specific Performance
subject: Clown
subject: Radio Drama
subject: Lazzi
subject: Practice as Research
subject: Devised Theatre
subject: Theater

description: This thesis explores the translation of physical theatre, specifically the comic clown routines known as lazzi, into audio performance. Using Practice as Research (PaR) and autoethnography, it investigates how movement, space, rhythm, and audience engagement can be conveyed through sound with minimal reliance on text. Grounded in traditions of devised theatre, clown, site-specific performance, and radio drama, and shaped by the author’s thirty years of professional practice, the inquiry responds to a gap in existing scholarship by proposing new methodologies for "sonic staging." Drawing on creative experiments and case studies—including The Daily Walk, Isobel and Oggie, and Intersections—the research develops a framework for constructing dynamic, movement-driven audio narratives. Influences from Jacques Lecoq, Bim Mason, Janet Cardiff, and Tim Crook inform the investigation, linking embodied performance with sound design and audience experience. The study reframes physical theatre not as a purely visual form but as an experiential one that can be fully realized in an auditory medium. Although the initial goal of recording a complete lazzi in audio form shifted during the research process, the work produced two lasting outcomes: a "playbook" for future sonic experiments and a set of "working tools" now integrated into professional practice. While Tim Crook identifies the assumption that radio drama evolves in response to stage theatre, this research demonstrated the reverse: radio theatre reconstituted the author's direction and philosophical outlook on stage performance. What began as a question to be answered has become a question now asked with every project—a rhetorical fulcrum for future exploration.
Water Management Modelling in the Simulation of Water Systems in Coastal Communities
Creators: name: Sara, Barghi
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Climate change
Sea level rise
stormwater
water systems

description: It is no longer a question of scientific debate that research declares our climate is changing. One of the most important and visible impacts of this phenomenon is sea level rise which has impacts on coastal cities and island communities. Sea level rise also magnifies storm surges which can have severely damaging impacts on different human made infrastructure facilities near the shorelines in coastal zones. In this research we are concerned about the proximity of water systems as one of the most vulnerable infrastructures in the coastal zones because of the impact of stormwater combining with sewage water. In Canada, the government has plans to address these issues, but to date, there needs to be further attention to stormwater management in coastal zones across the country. This research discusses the impacts of severe environmental events, e.g., hurricanes and storm surge, on the water systems of selected coastal communities in Canada. The purpose of this research is to model coastal zone water systems using the open source StormWater Management Modelling (SWMM) software in order to manage stormwater and system response to storms and storm surge on water treatment plants in these areas. Arichat on Isle Madame, Cape Breton, one of the most sensitive coastal zones in Canada, is the focal point case study for this research as part of the C-Change International Community-University Research Alliance (ICURA) 2009-2015 project.
Elementary Constructive Theory of Henselian Local Rings
Creators: name: García, Alonso
name: Emilia, M.
name: Lombardi
name: Henri
name: Perdry
name: Hervé
Publisher: name: arXiv
Year: 2022
Subjects: subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics
subject: 3J15, 03F55

description: We give an elementary theory of Henselian local rings and construct the Henselization of a local ring. All our theorems have an algorithmic content.
Bringing awareness to the workplace. Investigating the impact of an online mindfulness intervention on work situation awareness : a randomised wait-list control trial.
Creators: name: Sanchez-Walker, Emma Elizabeth
Publisher: name: University of Surrey
Year: 2020
Subjects: Work situation awareness
mindfulness
online intervention
work-related rumination
fatigue
sleep
anxiety

description: This study aimed to investigate the impact of a 4-week online mindfulness-based intervention on work situation awareness and other measures of occupational health. A randomised wait-list control design was used, with three and six month follow up. Participants were UK-based employees of a large international insurance company (N=163). Participants who completed the intervention (n=18) reported a significantly greater positive change, comparing before and after the intervention, in levels of work situation awareness, mindful awareness, sleep quality, anxiety, fatigue (acute and chronic) and work-related rumination, when compared to the change reported by wait-list control participants (n=65). The groups were combined for follow up (3 months, n=22; 6 months, n=26) due to attrition. The effects held at three months for affective rumination and problem solving pondering (measures of work-related rumination), and at six months for work situation awareness and anxiety. Mindful awareness was not significantly higher at three months but levels were significantly higher at six months than baseline. Participants who had dropped out were contacted by email and their responses analysed using content analysis. Reasons given included time limitations and a stressful work environment. This study provides support for online mindfulness interventions in increasing occupational wellbeing when completed. The high rates of attrition highlighted areas for future research around who is best suited to these types of interventions to best target resources.
acscatal.8b02440.pdf
Creators: name: Macro Man
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: 30601 Catalysis and Mechanisms of Reactions
subject: FOS: Chemical sciences
subject: 30603 Colloid and Surface Chemistry
subject: 30501 Free Radical Chemistry
subject: 30399 Macromolecular and Materials Chemistry not elsewhere classified
subject: Organic Chemistry
subject: 30305 Polymerisation Mechanisms
subject: 30306 Synthesis of Materials
subject: Supramolecular Chemistry

description: Biomimetic Glycoside Hydrolysis by a Microgel Templated with aCompetitive Glycosidase Inhibitor