cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Secure Dynamic Edge Resource Federation Architecture for Cross-Domain IoT Systems
Creators: name: Xu, Ronghua
name: Chen, Yu
name: Li, Xiaohua
name: Blasch, Erik
Publisher: name: arXiv
Year: 2022
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: The fast integration of 5G communication, Artificial Intelligence (AI), and Internet-of-Things (IoT) technologies is envisioned to enable Next Generation Networks (NGNs) for diverse smart services and user-defined applications for Smart Cities. However, it is still challenging to build a scalable and efficient infrastructure that satisfies the various performance, security, and management demands by heterogeneous IoT applications across multiple administrative domains. This paper presents a dynamic edge resource federation architecture, which integrates the concept of network slicing (NS) and blockchain to improve scalability, dynamicity, and security for multi-domain IoT applications. A NS-enabled dynamic edge resource federation framework adopts intelligent mechanisms to support efficient multi-domain service coordination that satisfies diverse Quality of Service (QoS) and security requirements. We propose a Hierarchical Integrated Federated Ledger (HIFL), which aims to guarantee decentralized security and privacy-preserving properties in multi-domain resource orchestration and service re-adjustment. As a secure-by-design solution, HIFL is promising to support efficient, trust and secured end-to-end IoT services. A preliminary proof-of-concept prototype has been implemented for comparing intra- and inter-domain performance expectations.
Sonnenfleckenzeichnung Nr. 20597.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.10.1960, erstellt von Helmut Müller.
Zusätzlich ist vermerkt: Sonnenturm
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sensory axon guidance molecules in avian skin
Creators: name: Cahoon-Metzger, Sharon M.
Publisher: name: University of Utah
Year: 2012
Subjects: Innervation

description: The goal of this dissertation research was to identify and begin to characterize the contribution of two classes of molecules, chondroitin sulfate proteoglycans (CSPGs) and neurotrophins (NTs) in patterning the innervation of avian skin. In particular, we investigate the role of these molecules in restricting axons to dermis in avian skin. The work described in Chapter 2 demonstrates that, while CSPGs contribute to the avoidance of chick epidermis by cutaneous sensory neurites, they are clearly not solely responsible. Chapter 3 details the possible inhibitory contribution of a member of an additional class of molecules, the neurotrophins (NTs), involved in patterning and maintaining sensory innervation. Our data implicate BDNF as an inhibitory component of chick epidermis that prevents sensory neurites from invading it. Neuronal development, which includes pathfinding, target selection and ramification with the correct target, is complex. Here we have utilized a system that allowed us to tease out at least part of the complex picture. By studying avian cutaneous innervation, we have proposed a model with multifactorial control or two classes of inhibitory guidance molecules (CSPGs and NTs) in this system. Using this more simplified system, it has become more increasingly clear how complex the scenario is-even at this level.
Inference of neutron-star properties with unified crust-core equations of state for parameter estimation
Creators: name: Davis, P. J.
name: Thi, H. Dinh
name: Fantina, A. F.
name: Gulminelli, F.
name: Oertel, M.
name: Suleiman, L.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Relating different global neutron-star (NS) properties, such as tidal deformability and radius, or mass and radius, requires an equation of state (EoS). Determining the NS EoS is therefore not only the science goal of a variety of observational projects, but it also enters in the analysis process; for example, to predict a NS radius from a measured tidal deformability via gravitational waves (GW) during the inspiral of a binary NS merger. To this aim, it is important to estimate the theoretical uncertainties on the EoS, one of which is the possible bias coming from an inconsistent treatment of the low-density region; that is, the use of a so called non-unified NS crust. We propose a numerical tool allowing the user to consistently match a nuclear-physics informed crust to an arbitrary high-density EoS describing the core of the star. We introduce an inversion procedure of the EoS close to saturation density that allows users to extract nuclear-matter parameters and extend the EoS to lower densities in a consistent way. For the treatment of inhomogeneous matter in the crust, a standard approach based on the compressible liquid-drop (CLD) model approach was used in our work. A Bayesian analysis using a parametric agnostic EoS representation in the high-density region is also presented in order to quantify the uncertainties induced by an inconsistent treatment of the crust. We show that the use of a fixed, realistic-but-inconsistent model for the crust causes small but avoidable errors in the estimation of global NS properties and leads to an underestimation of the uncertainties in the inference of NS properties. Our results highlight the importance of employing a consistent EoS in inference schemes. The numerical tool that we developed to reconstruct such a thermodynamically consistent EoS, CUTER, has been tested and validated for use by the astrophysical community.
description: 16 pages, 11 figures, accepted for publication in Astronomy and Astrophysics
Factors affecting an individual's admission into substance abuse treatment
Creators: name: Meyers, Kimberly Jo
Publisher: name: University of Utah
Year: 2012
Subjects: Substance abuse treatment

description: This study was looking at the factors that predicted an individualâ€™s initial entrance into substance abuse treatment. More specifically, this study looked at the influence between an individualâ€™s demographics, preferred drug of choice and number of Interim Groups attended and how these factors related to the individualâ€™s motivation to follow through with substance abuse treatment. The participants in this study were individuals who were on local substance abuse treatment waiting lists. An analysis of the data was conducted using logistic regression. The statistical results indicated that demographics and preferred drug of choice were not predictive of an individualâ€™s substance abuse treatment entry. Factors such as the number of Interim Groups attended and the individualâ€™s motivation and readiness for substance abuse treatment, as measured by the SOCRATES, were found to be significant, although they offered little predictive value regarding subsequent substance abuse treatment attendance. Research and clinical implications of these findings were discussed.
Two dimensional stability evaluation of a single entry longwall mining system
Creators: name: Rao, Thummala Venkat
Publisher: name: University of Utah
Year: 2012
Subjects: Mine safety
Sunnyside Coal Mine, Sunnyside, Utah
Coal mines and mining, Utah

description: The purpose of this study was to determine whether a single entry  is  as  safe for the development of longwail panels than the present double entry system at the Sunnyside Coal Mine near Sunnyside, Utah.  The work is a joint effort by the U.S. Bureau of Mines in cooperation with Kaiser Steel Corporation and the University of Utah. The study included field instrumentation and measurements as well as data processing and interpretation.  In-situ and laboratory tests were conducted to estimate the physical and mechanical properties of rock types present at the Sunnyside Mine.  Theoretical studies included prediction of stress concentrations and failure zones as well as comparisons between theoretical and field measurements of displacements about mine openings.  A finite element computer program was used for theoretical study, comparison of field data, and for simulation of face advance.
Wo und wie offen publizieren? Eine Einführung in Open Access
Creators: name: Rücknagel, Jessika
name: Schmeja, Stefan
Publisher: name: Zenodo
Year: 2020
Subjects: Open Access
Publikationsmodelle
Lizenzen
Open-Access-Modelle
Open-Access-Finanzierung

description: Präsentation im Rahmen der Reihe "Open Access Talk" des Projekts open-access.network am 23.07.2020 Das este Online-Seminar der monatlich stattfindenden Reihe "Open Access Talk" bot eine allgemeine Einführung zum Thema Open Access. Immer mehr Forschungsfördernde und -institutionen erwarten Open Access, den kostenfreien und rechtlich geregelten Zugang zu Forschungsergebnissen. Doch wie können Pubikationen der Community optimal verfügbar gemacht werden? Jessika Rücknagel (Projekt open-access.network, TIB) und Dr. Stefan Schmeja (Publikationsdienste, TIB) gaben Antworten auf diese und weitere Fragen: Welche Publikationsvarianten von Open Access gibt es? Welche kommen für mich in Frage? Wo kann ich gemäß Open Access publizieren? Wie finde ich ein passendes Journal? Was erwarten Forschungsfördernde?
Editing of hepatitis delta virus antigenomic RNA by recombinant human adenosine deaminases that act on RNA
Creators: name: Ley, Herbert Leonard
Publisher: name: University of Utah
Year: 2012
Subjects: Hepatitis Delta Virus
Saccharomyces Cerevisiae-based Protein

description: The adenosine deaminases that act on RNA (ADARs) are a family of RNA editing enzymes that catalyze the hydrolytic deamination of the C6 position of specific adenosines within the context of RNA.  The deamination reaction converts targeted adenosines to inosines.  Inosine, like guanosine, prefers to form basepairs with cytidine.  Consequently, when ADARs deaminated certain adenosines in the coding regions of cellular pre-messenger RNAs and Viral RNAs, the edited RNAs direct the translation of alternative forms of the encoded protein, often with significant biological consequences.  In order to study the action of human ADARs (hADARs) on cognate substrates in vitro, and to compare the enzymatic activity of different hADARs on defined substrates, a source of recombinant hADARs was needed.  The first experimental section of this dissertation describes a Saccharomyces cereviasiase-based protein expression system and associated purification protocol that readily yields biochemical quantities of pure, active hADAR1 and hADAR2.  The system and protocol represent a significant break-through in the field of ADAR enzymology that has already allowed others to investigate how ADARs catalyze their deamination reaction and target specific adenosines for modification.  ADAR-catalyzed editing of hepatitis delta virus (HDV) antigenomic RNA allows two forms of HDV antigen to be made from a single open reading frame.  Edition converts an amber stop codon (UAG) to a tryptophan (W) codon (UIG) at the so-called amber/W site.  Edited RNAs direct the translation of antigen that is 19 amino acids longer than that encoded by unedited RNAs.  The shorter from of the antigen is required for viral replication whereas the longer form inhibits replication and is required for packaging.  Hence, the life cycle of HDV is dependent upon editing by hASARs.  The second experimental section of this dissertation describes the results of side-by-side in vitro amber/W site editing reactions catalyzed by recombinant hADAR1 and hADAR2.  These studies revealed significant differences in the abilities of the two hADARs to edit substrates bearing mutations proximal to the amber/W site, and differences in the selectivity of editing by the two enzymes.  These data, along with others published results, implicate hADAR1 as being responsible for amber/W site editing in vivo.
Methylphenidate, the vesicular monoamine transporter-2 and neurotoxicity
Creators: name: Sandoval, Ver©nica
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Dopamine

description: It seems that multiple high-dose administrations of methamphetamine (METH) cause persistent dopamine (DA) deficits. These DA deficits are highly selective for nerve terminals in the basal ganglia system. The development of neurodegenerative disorders, such as Parkinson's disease (PD), is linked to DA deficits in nigrostriatal neurons; thus, METH-induced toxicity is frequently used as a model for PD. Several investigative groups have suggested that METH causes DA deficits because it increases intraneuronal DA levels, and subsequently causes formation of reactive oxygen species (ROS). Our laboratory and others have hypothesized that agents that decrease intraneuronal DA concentrations by increasing its sequestration within neuronal vesicles via the vesicular monoamine transporter-2 (VMAT-2) may be neuroprotective. We hypothesize that DA reuptake inhibitors, like methylphenidate (MPD), may be neuroprotective against METH-induced toxicity since vesicular DA sequestration is enhanced, thereby, decreasing intraneuronal DA and subsequent formation of ROS. Hence, this dissertation will test the hypothesis that MPD increases vesicular monoamine transport, and thereby protects against METH-induced monoaminergic toxicity. This dissertation demonstrates that MPD increased vesicular DA uptake and binding of the VMAT-2 ligand, dihydrotetrabenazine (DHTBZ), in a dose- and time-dependent manner in purified striatal vesicles prepared from treated rats. MPD treatment increased and decreased VMAT-2 immunoreactivity in striatal vesicle subcellular and plasmalemmal membrane fractions, respectively. The MPD-induced increase in both VMAT-2 immunoreactivity and DHTBZ binding was attenuated by pretreatment with either the DA D1
Sonnenfleckenzeichnung Nr. 20629.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.11.1960, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Syringophilopsis mimidus Sikora, Fajfer and Skoracki 2011
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis mimidus

description: Syringophilopsis mimidus Sikora, Fajfer and Skoracki, 2011
Syringophilopsis mimidus Sikora et al., 2011: 30, figs. 1–6. Types deposited in AMU, ZSM and ZISP, examined. Type host: Margarops fuscatus (Vieillot) (Passeriformes: Mimidae). Type locality: Central America.
Additional material. Four females and 2 males (UMMZ BMOC 81-0717-1) from Dumetella carolinensis (Linnaeus) (Passeriformes: Mimidae), USA: Pennsylvania, Warren Co., 3 mi W. Pittsfield, 17 July 1981, coll. B. M. OConnor, all material in UMMZ; 4 females and 1 male (FMNH NU4251B) from same host species, USA: Florida, Leon Co., Tall Timbers Research Station, 24 April 1959, coll. H. L. Stoddard, all material in FMNH.
Host and distribution. Margarops fuscatus (Vieillot) (Mimidae) from unknown locality in Central America (Sikora et al. 2011), Dumetella carolinensis (Linnaeus) (Mimidae) [new host] from USA (Florida, Pennsylvania) (present paper).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on pages 473-474, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.11.1960, erstellt von Emilia Tifrea, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.12.1960, erstellt von Irina Soru, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.08.1960, erstellt von V. Rusin am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Sonnenfleckenzeichnung Nr. 20622.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.11.1960, erstellt von Helmut Müller.
Zusätzlich ist vermerkt: Sonnenturm
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.11.1960, erstellt von Metin Hotinli an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.10.1960, erstellt am Sonnenobservatorium Kanzelhöhe, Kärnten
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage im Sonnenobservatorium Kanzelhöhe in Sattendorf, Österreich. Instrument: Heliostat mit Refraktor Eigenbau (Öffnung 110mm, f = 1650mm, projiziertes Sonnenbild D = 25cm)
Syringophilopsis icteri Bochkov and Galloway 2001
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis icteri

description: Syringophilopsis icteri Bochkov and Galloway, 2001
Syringophilopsis icteri Bochkov and Galloway, 2001: 2019, figs. 5 and 6; Skoracki et al. 2011a: 17. Type material in CNC and ZISP, examined.
Type host: Icterus galbula (Linnaeus) (Passeriformes: Icteridae). Type locality: Canada (Manitoba).
Additional material. Three females (UMMZ BMOC #77-0519-1) from Icterus galbula (Linnaeus) (Passeriformes: Icteridae), USA: New York, Tompkins Co., Newfield, 19 May 1977, coll. B. M. OConnor, all material in UMMZ; 1 female (UMMZ BMOC #83-0526-1) from Icterus spurius (Linnaeus) (Passeriformes: Icteridae), USA: Michigan, Livingston Co., Green Oak Twp., Sect. 2, 1–7 May 1983, coll. A. Zinn, specimen in UMMZ.
Host and distribution. Icterus bullocki (Swainson) (Icteridae) from USA (California) (Skoracki et al. 2011a), I. galbula (Linnaeus) from Canada (Manitoba) (Bochkov & Galloway 2001) and USA (New York) (present paper), I. spurius (Linnaeus) [new host] from USA (Michigan) (present paper).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 473, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Syringophiloidus molothrus Skoracki, Flannery and Spicer 2009
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Syringophilidae
Syringophiloidus
Syringophiloidus molothrus

description: Syringophiloidus molothrus Skoracki, Flannery and Spicer, 2009
Syringophiloidus molothrus Skoracki et al., 2009b: 66, figs. 1–5. Type deposited in AMU, examined. Type host: Molothrus ater (Boddaert) (Passeriformes: Icteridae). Type locality: USA (Texas).
Additional material. Six females and 1 male (UMMZ BMOC #81-0610-2) from Icterus galbula (Linnaeus) (Passeriformes: Icteridae), USA: Michigan, Washtenaw Co., 3 mi. W. Dexter, 10 June 1981, coll. B. M. OConnor, all material in UMMZ.
Host and distribution. Icterus galbula (Linnaeus) (Icteridae) [new host] from USA (Michigan) (present paper), Molothrus ater (Boddaert) (Icteridae) from USA (Texas) (Skoracki et al. 2009b).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 466, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.12.1960, erstellt am Sonnenobservatorium Kanzelhöhe, Kärnten
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage im Sonnenobservatorium Kanzelhöhe in Sattendorf, Österreich. Später wurden ergänzende Angaben aufgrund weiterer Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Instrument: Heliostat mit Refraktor Eigenbau (Öffnung 110mm, f = 1650mm, projiziertes Sonnenbild D = 25cm)
Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation
Creators: name: Shiyang Liu
Publisher: name: figshare
Year: 2020
Subjects: Cancer
Computational Biology

description: 1. Full reference transcriptome GTF including novel lncRNAs from orthotopic model of RNF43-mutant pancreatic adenocarcinoma (HPAF-II).

2. Timecourse RNA-seq of response to PORCN inhibition (ETC-159) in an orthotopic model of RNF43 mutant pancreatic adenocarcinoma (HPAF-II). RNA-seq performed at multiple timepoints (0 hrs, 3 hrs, 8 hrs, 16 hrs, 32 hrs, 56 hrs and 7 days).
Isolation of a soluble protein resembling elastin
Creators: name: Smith, Don Wilder
Publisher: name: University of Utah
Year: 2012

description: There are strong indications of a defect in elastogenesis in copper deficiency.  This is manifested by histologic lesions of the elastic membranes.  Furthermore, analysis of stretch moduli of copper deficient aortic rings indicate a marked decrease in tensile strength.  Elastin isolated from copper deficient aortas has an increased solubility in formic acid and the amino acid composition of this elastin indicates a decrease in the cross-linking amino acids.  The basis of the defective cross-linking is thought to be the failure of the oxidation and condensation of epsilon-amino groups of lysine residues preexisting in straight chain elastin precursors.  An excess of unidentified salt soluble proteins in these aortas has suggest that a soluble elastin precursor may accumulate as a result of a block in the cross-linking reaction.  The reversible coacervation of a cold soluble protein in this fraction upon warming and cooling has provided a means of partial purification of this protein.  Aortas from copper deficient swine were extracted in buffered 1 M NaC1 solutions overnight as 4 degrees C.  The salt extracts were filtered cold and the filtrate was further clarified by centrifuging at 100,000xg at 4 degrees C for 30 minutes.  The filtrate was warmed to 23 degrees and the heat precipitable fraction was collected by centrifuging for 1 hour at 22,000xg.  The precipitate was redissolved and reprecipitated twice more to obtain a clear solution.  Disc electrophoresis indicated the presence of one major protein an amino acid analysis revealed that its composition was basically close to that of elastin.  The high content of the amino acid and high content of lysine indicate that the soluble protein may be a precursor of insoluble elastin.  The reversible heat precipitation shown by the soluble protein found in copper deficient aortas is also exhibited by alpha-elastin; a large soluble degradation product of insoluble elastin produced by partial hydrolysis.  This unusual property of reversible heat precipitation at room temperature is not shown by any other protein.
Giant caloric effects in spin chain materials
Creators: name: Zvyagin, A. A.
name: Slavin, V. V.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The giant electro- and elasto-caloric effects in spin chain materials are predicted. The theory is based on the exact quantum mechanical solution of the problem. It is shown that the giant jumps in the entropy and the temperature caused by the caloric effect are weakly affected by the initial temperature. The effect can be used for the cooling of new quantum devices (like systems of qubits in quantum computers). On the other hand, since large changes are predicted in the narrow neighborhood of the critical point, the predicted effect can be used in ultra-sensitive electric and stress sensors for modern microelectronics.
description: Typo is corrected
Sonnenfleckenzeichnung Nr. 20598.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.10.1960, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Wnt-regulated lncRNAs GTF and expression files
Creators: name: Shiyang Liu
Publisher: name: figshare
Year: 2020
Subjects: Cancer

description: 1. Full reference transcriptome GTF including novel lncRNAs from orthotopic model of RNF43-mutant pancreatic adenocarcinoma (HPAF-II).

2. Timecourse RNA-seq of response to PORCN inhibition (ETC-159) in an orthotopic model of RNF43 mutant pancreatic adenocarcinoma (HPAF-II). RNA-seq performed at multiple timepoints (0 hrs, 3 hrs, 8 hrs, 16 hrs, 32 hrs, 56 hrs and 7 days).
Fundamental analysis of relative permeability and heterogeneity on carbon dioxide storage and plume migration
Creators: name: Moodie, Nathan David
Publisher: name: University of Utah
Year: 2013
Subjects: carbon dioxide
heterogeneity
multiphase flow
relative permeability
sequestration

description: A critical aspect of geologic carbon storage, a carbon-emissions reduction method under extensive review and testing, is the ability to simulate multiphase CO2 flow and transport. Relative permeability is a flow parameter particularly critical for accurate forecasting of multiphase behavior of CO2 in the subsurface. Specifically, for clastic formations, small-scale (cm) bedding planes can have a significant impact on multiphase CO2-brine fluid flow, depending on the relative permeability relationship assumed. Such small-scale differences in permeability attributable to individual bedding planes may also have a substantial impact on predicted CO2 storage capacity and long-term plume migration behavior. A major goal of this study was to evaluate and calibrate relative permeability models against experimental data to improve simulation capability. We analyzed previouslypublished laboratory-scale measurements of relative permeability of Berea sandstone, and developed a corresponding three dimensional simulation model of those measurements. The simulation model was created in the TOUGHREACT reactive transport simulator, and we elucidated best-fit relative permeability formulations to match the experimental data. Among several functions evaluated, best-fits between simulation results and experimental observations were achieved with a calibrated van Genuchten-Mualem formulation. To extend the analysis to a more heterogeneous medium, we applied the best-fit relative permeability formulations to a new model of a small-scale Navajo Sandstone reservoir. The model was one cubic meter in size, with eight individual lithofacies of differing permeability, gridded to mimic small-scale bedding planes. For this model we iv assumed that each lithofacies exhibits a random permeability field, resulting in a model with heterogeneous lithofacies. We then evaluated four different relative permeability functions to quantify their impact on flow results for each model, with all other parameters maintained constant. Results of this analysis suggest that CO2 plume movement and behavior are significantly dependent on the specific relative permeability formulation assigned, including the assumed irreducible saturation values of CO2 and brine. More specifically, different relative permeability formulations translate to significant differences in CO2 plume behavior.
Comparison of the effect of computer and manual reminders of compliance with a mental health clinic practice guideline
Creators: name: Cannon, Dale S.
Publisher: name: University of Utah
Year: 2012
Subjects: Case Walker
Decision Support System
Major Depressive Disorder

description: The objective of this study was to evaluate the relative effectiveness of a computerized decision support system and a manual reminder system on the implementation of a Major Depressive Disorder clinical practice guideline in an outpatient mental health clinic. The study was a randomized clinical trail in which 76 patients were randomly assigned within clinician to one of the two experimental conditions. The first condition was a checklist inserted in the paper medical record, and the second was a computerized decision support system entitled the CaseWalker. The Case Walker reminded clinicians when guideline-recommended screening for mood disorder was due, ensured the fidelity of the diagnosis of Major Depressive Disorder with the Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) criteria, and generated a progress note. The CaseWalker, compared to the paper checklist, resulted in higher screening rate for mood disorder (86.5% vs. 64.1%, p= .018) and more consistent application of DSM-IV criteria (100% vs. 5.6%, p< .001). Clinician acceptance of the CaseWalker was good, with three of four clinicians strongly preferring it to the paper checklist. Thus, computer reminders were shown to be superior to manual reminders in supporting the implementation of a depression clinical practice guideline in an outpatient mental health clinic. A previous review of the literature on  reminder systems concluded there is insufficient evidence for the superiority of computer reminders over manual reminders. However, the results of the present study provide further empirical evidence that computer reminders are more effective than manual reminders. Further, this study is believed to be the first randomized controlled trial of the efficacy of computerized reminders in a mental health clinic.
Sonnenfleckenzeichnung Nr. 20640.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.12.1960, erstellt von Helmut Müller
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Kern-Merz-Refraktor.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Unter Umständen sind Angaben zu Protuberanzen vermerkt
Design of a versatile and disposable microfluidic chip for automated sample preparation and nucleic acid extraction
Creators: name: Minson, John Glenn
Publisher: name: University of Utah
Year: 2013

description: Significant progress has been made in recent years advancing microfluidic extraction systems for nucleic acids (NAs). However, much remains to be done in the area of sample preparation as it presents significant challenges and additional steps before nucleic acids can be extracted. These difficulties prompted the design of a versatile, disposable extraction system that was robust enough to handle a wide range of raw biological samples and perform the necessary sample preparation protocols. This design was accomplished through an iterative design process, building on Johnsons's polydimethylsiloxane (PDMS) extraction chip [1]. With a primary focus on reducing cost and improving manufacturing time, a new chip was designed and constructed from 3 layers of laminated polycarbonate and a silicone flexible membrane layer. Four features were adapted or redesigned to make the chip fully function: the microvalves, fluid inlet connections, reservoir-pumps and microfilter. Significant design changes were used to make this integration possible. The most notable change involved removing the lower portion of Johnson's PDMS chip[1] and integrating it as a permanent fixture on the pneumatic actuation system. This modification greatly simplified the chip, minimizing cost and manufacturing time while allowing the microvalves and reservoir-pumps to function exactly as before. In addition to designing a new extraction chip, the supporting pneumatic actuation system was redesigned and rebuilt as well. Pneumatic failures in Johnson's pneumatic machine were common, which were caused by an excessive amount of flexible tubing and connectors. To create a more reliable pneumatic machine, a central manifold was constructed with access to the necessary pressure sources. The new system was tested with water for basic fluidic functionality. It successfully demonstrated working valves, reservoir pumps and filter flow. Subsequent testing revealed the successful extraction of DNA from a purified sample. The new extraction system is simpler, easier to use and fabricated in 1/16th of the time and produced for 1/60th of the cost of Johnson's PDMS chip.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.10.1960, erstellt von Vasile Dinulescu, Observatorium Bukarest
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1960

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Astronomischen Observatorium Bukarest, Solarsektor, Rumänien. Instrument: Zeiss-Refraktor (Öffnung 130mm, f = 1950mm, projiziertes Sonnenbild D = 25cm)
Syringophilopsis sturnellus Skoracki, Hendricks and Spicer 2011
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis sturnellus

description: Syringophilopsis sturnellus Skoracki, Hendricks and Spicer, 2011
Syringophilopsis sturnellus Skoracki et al., 2011a: 13, figs. 25–36. Types deposited in USNM and AMU, examined. Type host: Sturnella neglecta Audubon (Passeriformes: Icteridae). Type locality: USA (Arizona).
Host and distribution. Sturnella neglecta Audubon (Icteridae) from USA (Arizona) (Skoracki et al. 2011a).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 474, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Syringophilopsis elongatus
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis elongatus

description: Syringophilopsis elongatus (Ewing, 1911)
Syringophilus elongatus Ewing, 1911: 39. Type material lost (in Kethley: 21).
Syringophilus icteridae Clark, 1964: 89, figs. 30 and 31. Material deposited in FMNH, examined.
Syringophilopsis elongatus, Kethley 1970: 21, figs. 10 and 11; Bochkov & Galloway 2001: 2023; Skoracki et al. 2008: 299, 2011: 19.
Type host: Agelaius phoeniceus (Linnaeus) (Passeriformes: Icteridae). Type locality: USA.
Additional material. One female (FMNH A600507-6) from Agelaius phoeniceus (Linnaeus) (Passeriformes: Icteridae), USA: Nebraska, Saline Co., Crete, 7 May 1960, coll. N. Braasch, specimen in FMNH; 2 females (FMNH uncatalogued) from Quiscalus quiscula (Linnaeus) (Passeriformes: Icteridae), USA: Nebraska, Lincoln, 4 September 1944, coll. D. Gates, all material in FMNH.
Host and distribution. Agelaius phoeniceus (Linnaeus) (Icteridae) from USA (Arizona, California, Georgia, Maryland, Nebraska) (Ewing 1911; Clark 1964; Kethley 1970; Skoracki et al. 2008, 2011a; present paper) and Canada (Manitoba) (Hood & Welch 1980), Euphagus carolinus (Muller) from USA (Maryland) (Clark 1964), Euphagus cyanocephalus (Wagler) from USA (California) (Skoracki et al. 2008), Quiscalus quiscula (Linnaeus) from USA (Maryland, Nebraska) (Clark 1964; present paper) and Canada (Manitoba) (Bochkov & Galloway 2001), Quiscalus mexicanus (Gmelin) from USA (Texas) (Casto 1976).
Remark. Mite species recorded by Casto (1976) from Pheucticus melanocephalus (Cardinalidae) and determined as S. elongatus is presently described as a new species, S. wilsoni sp. nov. (see below).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 473, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Syringophilopsis passerinae
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis passerinae

description: Syringophilopsis passerinae (Clark, 1964)
Syringophilus passerinae Clark, 1964: 91, figs. 3, 26 and 27; Skoracki et al. 2011a: 17, figs. 39–44. Types deposited in FMNH, examined.
Syringophilopsis passerina, Kethley 1970: 23.
Type host: Passerina cyanea (Linnaeus) (Passeriformes: Cardinalidae). Type locality: USA (Maryland).
Additional material. Six females (FMNH uncatalogued) from Passerina cyanea (Linnaeus) (Passeriformes: Cardinalidae), USA: Florida, Leon Co., 1 October 1957, coll. J. B. Kethley, all material in FMNH; 5 females (FMNH uncatalogued) from Passerina caerulea (Linnaeus) (Passeriformes: Cardinalidae), USA: Georgia, Jefferson Co., Wrens, 12 May 1968, coll. R. Heard, all material in FMNH.
Host and distribution. Passerina caerulea (Linnaeus) [new host] from USA (Georgia) (present paper), P. ciris (Linnaeus) from USA (Texas) (Skoracki et al. 2011a). P. cyanea (Linnaeus) (Cardinalidae) from USA (Florida, Maryland, Texas) (Clark 1964; Skoracki et al. 2011a; present paper).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 474, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Syringophilopsis tyranni Bochkov and Galloway 2004
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis tyranni

description: Syringophilopsis tyranni Bochkov and Galloway, 2004
Syringophilopsis tyranni Bochkov and Galloway, 2004: 35, figs. 19–24 and 26–29. Types deposited in CNC, JBWM, AMU and ZISP, examined.
Type host: Tyrannus tyrannus (Linnaeus) (Passeriformes: Tyrannidae). Type locality: Canada (Manitoba).
Additional material. Nine females (AMU-SYR.280) from Myiarchus cinerascens (Lawrence) (Passeriformes: Tyrannidae), USA: California, Riverside Co., 6 April 2006, coll. G. S. Spicer (field no. GSS 2200), all material in AMU; 4 females (AMU-SYR.281) from Tyrannus forficatus (Gmelin) (Tyrannidae), USA: Texas, Johnson Co., 21 March 2004, coll. G. S. Spicer (field no. GSS 2017), all material in AMU; 1 female and 2 males (FMNH uncatalogued) from Tyrannus dominicensis (Gmelin) (Tyrannidae), USA: Florida, Taylor, Perry Co., 15 July 1960, coll. Atyeo, Braasch & Orwig, all material FMNH.
Host and distribution. Myiarchus cinerascens (Lawrence) (Tyrannidae) from USA (California, Texas) (Skoracki et al. 2008; present paper), M. crinitus (Linnaeus) from USA (Texas) (Skoracki et al. 2008), Myiopagis subplacens (Sclater) (Tyrannidae) from Peru (Glowska 2014), Tyrannus dominicensis (Gmelin) (Tyrannidae) [new host] from USA (Florida) (present paper), T. forficatus (Gmelin) [new host] from USA (Texas) (present paper), T. tyrannus (Linnaeus) (Tyrannidae) from Canada (Manitoba) (Bochkov & Galloway 2004), T. verticalis Say from USA (California) (Skoracki et al. 2008).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 474, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Syringophilopsis turdi
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis turdi

description: Group species turdi
FEMALE: Setae f1 and h1 short and several times shorter than f2 and h2.
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 477, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257
Computerized protocol for weaning patients from mechanical ventilation using pressure support
Creators: name: Randolph, Adrienne G.
Publisher: name: University of Utah
Year: 2012
Subjects: Pressure Support
Computerized Protocol
Bedside Testing

description: An explicitly defined, open-loop computerized protocol to wean patients from mechanical ventilatory support using the pressure support mode was developed and tested.  The logic in the protocol was refined through review of the literature, consensus of experts, computer simulation, bedside testing.  An initial protocol in which the pressure support level was adjusted based upon a respiratory rate threshold was tested in five patients using paper glow diagrams.  Users found the paper protocol difficult to follow and compliance was poor.  Transient tachypnea prevented efficient weaning.  All patients were removed from the protocol be extubation.  A modification of the rapid shallow breathing test was used as the threshold variable upon which to adjust the level of pressure support.  This logic was computerized and tested in 10 patients for a total of 1075 hours.  The compliance rate with the 1394 instructions generated by the protocol was 95%, and 96% of the instructions were correct.  Development of this protocol had many benefits beyond the generation of an explicit set of rules for weaning patient s for mechanical ventilation.  Protocol development requires that all variables be scrutinized for accuracy, reliability, and fairness of measurement.  This enforced standardization of data elements improves reproducibility.  User acceptance of protocols is enhanced by integration into the normal workflow, rapid response to and correction of problem during protocol application, and by giving users feedback on patient progress
Syringophilopsis certhiae Skoracki, Hendricks and Spicer 2011
Creators: name: Skoracki, Maciej
name: Spicer, Greg S.
name: Oconnor, Barry M.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Syringophilidae
Syringophilopsis
Syringophilopsis certhiae

description: Syringophilopsis certhiae Skoracki, Hendricks and Spicer, 2011
Syringophilopsis certhiae Skoracki et al., 2011a: 6, figs. 1–12. Types deposited in USNM and AMU, examined. Type host: Certhia americana Bonaparte (Passeriformes: Certhiidae). Type locality: USA (California).
Host and distribution. Certhia americana Bonaparte (Certhiidae) from USA (California) (Skoracki et al. 2011a).
description: Published as part of Skoracki, Maciej, Spicer, Greg S. & Oconnor, Barry M., 2016, A systematiC review of the subfamily Syringophilinae (ACari: Syringophilidae) of the NearCtiC region. Part 1: quill mites assoCiated with passerines (Aves: Passeriformes), pp. 451-494 in Zootaxa 4084 (4) on page 479, DOI: 10.11646/zootaxa.4084.4.1, http://zenodo.org/record/1052257