cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Constraining the systematics of (acoustic) wave heating estimates in the solar chromosphere
Creators: name: Molnar, Momchil E.
name: Reardon, Kevin P.
name: Cranmer, Steven R.
name: Kowalski, Adam F.
name: Milic, Ivan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Acoustic wave heating is believed to contribute significantly to the missing energy input required to maintain the solar chromosphere in its observed state. We studied the propagation of waves above the acoustic cutoff in the upper photosphere into the chromosphere with ultraviolet and optical spectral observations interpreted through comparison with three dimensional radiative magnetohydrodynamic (rMHD) \emph{Bifrost} models to constrain the heating contribution from acoustic waves in the solar atmosphere. Sit-and-stare observations taken with the Interface Region Imaging Spectrograph (IRIS) and data from the Interferometric BIdimensional Spectrograph (IBIS) were used to provide the observational basis of this work. We compared the observations with synthetic observables derived from the Bifrost solar atmospheric model. Our analysis of the \emph{Bifrost} simulations show that internetwork and enhanced network regions exhibit significantly different wave propagation properties, which are important for the accurate wave flux estimates. The inferred wave energy fluxes based on our observations are not sufficient to maintain the solar chromosphere. We point out that the systematics of the modeling approaches in the literature lead to differences which could determine the conclusions of this type of studies, based on the same observations.
description: Accepted for publication in ApJ
Appendices - Who You Gonna Call: Analyzing the Run-Time Call-Site Behavior of Ruby Applications
Creators: name: Kaleba, Sophie
name: Larose, Octave
name: Jones, Richard
name: Marr, Stefan
Publisher: name: Zenodo
Year: 2022

description: This document contains the appendices part of the "Who You Gonna Call: Analyzing the Run-Time Call-Site Behavior of Ruby Applications" paper, published as part of the Dynamic Languages Symposium 2022 (https://2022.splashcon.org/track/dls-2022-papers). Full paper DOI: https://doi.org/10.1145/3563834.3567538
Apoptosis Is the Essential Target of Selective Pressure against p53, whereas Loss of Additional p53 Functions Facilitates Carcinoma Progression
Creators: name: Yang, C.
name: Van Dyke, T.
name: Lu, X.
name: Simin, K.
name: Yin, C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The high frequency of p53 mutation in human cancers indicates the important role of p53 in suppressing tumorigenesis. It is well established that the p53 regulates multiple, distinct, cellular functions such as cell cycle arrest and apoptosis. Despite intensive studies, little is known about which function is essential, or if multiple pathways are required, for p53-dependent tumor suppression in vivo. Using a mouse brain carcinoma model that shows high selective pressure for p53 inactivation, we found that even partially abolishing p53-dependent apoptosis by Bax inactivation was sufficient to significantly reduce the selective pressure for p53 loss. This finding is consistent with previous reports that apoptosis is the primary p53 function selected against during Eμ-myc induced mouse lymphoma progression. However, unlike observed in the Eμ-myc induced lymphoma model, attenuation of apoptosis is not sufficient to phenocopy the aggressive tumor progression associated with complete loss of p53 activity. We conclude apoptosis is the primary tumor suppressive p53 function and the ablation of additional p53 pleiotropic effects further exacerbates tumor progression.
Dynkin diagrams of rank 20 on supersingular K3 surfaces
Creators: name: Shimada, Ichiro
name: Zhang, De-Qi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14J28

description: We classify normal supersingular K3 surfaces Y with total Milnor number 20 in characteristic p, where p is an odd prime that does not divide the discriminant of the Dynkin type of the rational double points on Y.
description: SCIENCE CHINA Mathematics, special issue for the Proceedings of Algebraic Geometry in East Asia, Beijing, China, October 2013 (to appear). This paper appeared in the preprint form in the homepage of the first author in year 2005
On the application of Jucys-Murphy operators in the Hubbard model
Creators: name: Jakubczyk, Dorota
name: Jakubczyk, Paweł
name: Kravets, Yevgen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The operator techniques based on the Jucys-Murphy operators were applied in the procedure of an immediate diagonalization of the one-dimensional Hubbard model. The Young orthogonal basis was given by the irreducible basis of the symmetric group acting on the set of nodes of the magnetic chain. The example of the attractive Hubbard model at the half-filled magnetic rings case was considered where the group $SU(2)\times SU(2)$ acts within the spin and pseudo-spin space. These techniques significantly reduced size of the eigenproblem of the Hubbard Hamiltonian.
description: 10 pages
Low-Effort Specification Debugging and Analysis
Creators: name: Ehlers, Rüdiger
name: Raman, Vasumathi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Software Engineering (cs.SE)
subject: Logic in Computer Science (cs.LO)
subject: Robotics (cs.RO)
subject: FOS: Computer and information sciences

description: Reactive synthesis deals with the automated construction of implementations of reactive systems from their specifications. To make the approach feasible in practice, systems engineers need effective and efficient means of debugging these specifications. In this paper, we provide techniques for report-based specification debugging, wherein salient properties of a specification are analyzed, and the result presented to the user in the form of a report. This provides a low-effort way to debug specifications, complementing high-effort techniques including the simulation of synthesized implementations. We demonstrate the usefulness of our report-based specification debugging toolkit by providing examples in the context of generalized reactivity(1) synthesis.
description: In Proceedings SYNT 2014, arXiv:1407.4937
Unveiling hidden active nuclei in MaNGA star-forming galaxies with HeII$λ$4686 line emission
Creators: name: Tozzi, Giulia
name: Maiolino, Roberto
name: Cresci, Giovanni
name: Piotrowska, Joanna M.
name: Belfiore, Francesco
name: Curti, Mirko
name: Mannucci, Filippo
name: Marconi, Alessandro
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Nebular HeII$λ$4686Å~line emission is useful to unveil active galactic nuclei (AGN) residing in actively star-forming (SF) galaxies, typically missed by the standard BPT classification. Here we adopt the HeII diagnostic to identify hidden AGN in the Local Universe using for the first time spatially-resolved data from the Data Release 15 of the Mapping Nearby Galaxies at APO survey (MaNGA DR15). By combining results from HeII and BPT diagnostics, we overall select 459 AGN host candidates ($\sim$10% in MaNGA DR15), out of which 27 are identified as AGN by the HeII diagram only. The HeII-only AGN population is hosted by massive (M$_*\gtrsim10^{10}$ M$_{\odot}$) SF Main Sequence galaxies, and on average less luminous than the BPT-selected AGN. Given the HeII line faintness, we revisit our census accounting for incompleteness effects due to the HeII sensitivity limit of MaNGA. We thus obtain an overall increased fraction (11%) of AGN in MaNGA compared to the BPT-only census (9%), which further increases to 14% for galaxies more massive than $10^{10}$ M$_{\odot}$; interestingly, on the SF Main Sequence the increase is by about a factor of 2. A substantial number of AGN in SF galaxies points to significant, coeval star formation and black hole accretion, consistently with results from hydrodynamical simulations and with important implications on quenching scenarios. In view of exploring unprecedented high redshifts with JWST and new ground-based facilities, revisiting the standard BPT classification through novel emission-line diagnostics is fundamental to discover AGN in highly SF environments.
description: 13 pages, 12 figures. Accepted for publication in MNRAS
Oxygen exchange by entire root systems of Cyperus involucratus and Eleocharis sphacelata
Creators: name: Sorrell, Brian K
name: Brix, H
name: Orr, P. T
Publisher: name: La Trobe
Year: 2023

description: Murray-Darling Freshwater Research Centre

MDFRC item.

Net oxygen exchange between root systems of the sedges Cyperus involucratus Rottb. and Eleocharis sphacelata R.Br. was measured in a bi-compartment apparatus, fitted with a polargraphic oxygen electrode and a platinum wire electrode in the root chamber. The roots of both species consumed oxygen from water in the root chamber with no net exchange when the oxygen partial pressure (ρO2) in the chamber was zero. Rates of oxygen uptakes by roots of intact plants were always lower than excised roots, suggesting a contribution by oxygen transport from the shoots to the root respiratory demand. The contribution of oxygen transported from the shoots increased with diminishing ρO2 in the root medium, approaching the total oxygen demand as ρO2 fell to zero. The roots released oxygen when titanium (III) citrate redox buffer (EH=-350mV) was used in the root chamber to mimic the redox potential of natural sediments. Rates of oxygen release into the reduced solutions were 21 ± 5 and 55 ± 7 µmol O2 hr-1 g-1 root dry weight in the dark (mean values ± 1 standard deviation). These results suggest that an agitated body of water alone is not a suitable medium for measuring root oxygen release by entire root systems. A solution with high oxygen demand is more appropriate.
Responses of billabong rotifer communities to inundation
Creators: name: Tan, Lor-Wai
name: Shiel, Russell J
Publisher: name: La Trobe
Year: 2023

description: Murray-Darling Freshwater Research Centre

MDFRC item.

Daily plankton collections were taken from a billabong of the River Murray for two weeks prior to inundation in March 1990, and continued for ten days after flooding. Quantitative responses of the plankton community and the component species were analysed against measured environmental variables and between species. Rotifers and copepod nauplii were the predominant net plankton (> 53 µm). Significant negative or positive responses to inundation were detected for most common taxa of 63 rotifer species recorded. A four-fold dilution from intrusion of river water masked rapid population increases. Opportunistic responses to inundation appear to be a survival strategy in the highly unpredictable billabong environment.
C/EBP , C/EBP  Oncoproteins, or C/EBP  Preferentially Bind NF- B p50 Compared with p65, Focusing Therapeutic Targeting on the C/EBP:p50 Interaction
Creators: name: Friedman, A. D.
name: Dooher, J. E.
name: Paz-Priel, I.
name: Baldwin, A. S.
name: Houng, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Canonical NF-κB activation signals stimulate nuclear translocation of p50:p65, replacing inhibitory p50:p50 with activating complexes on chromatin. C/EBP interaction with p50 homodimers provides an alternative pathway for NF-κB target gene activation, and interaction with p50:p65 may enhance gene activation. We previously found that C/EBPα cooperates with p50 but not p65 to induce Bcl-2 transcription and that C/EBPα induces Nfkb1/p50 but not RelA/p65 transcription. Using p50 and p65 variants containing the FLAG epitope at their N- or C-termini, we now demonstrate that C/EBPα, C/EBPα myeloid oncoproteins, or the LAP1, LAP2, or LIP isoforms of C/EBPβ have markedly higher affinity for p50 in comparison to p65. Deletion of the p65 trans-activation domain did not increase p65 affinity for C/EBPs, suggesting that unique residues in p50 account for specificity, and clustered mutation of HSDL in the “p50 insert” lacking in p65 weakens interaction. Also, in contrast to Nfkb1 gene deletion, absence of the RelA gene does not reduce Bcl-2 or Cebpa RNA in unstimulated cells or prevent interaction of C/EBPα with the Bcl-2 promoter. Saturating mutagenesis of the C/EBPα basic region identifies R300 and nearby residues, identical in C/EBPβ, as critical for interaction with p50. These findings support the conclusion that C/EBPs activate NF-κB target genes via contact with p50 even in the absence of canonical NF-κB activation and indicate that targeting C/EBP:p50 rather than C/EBP:p65 interaction in the nucleus will prove effective for inflammatory or malignant conditions, alone or synergistically with agents acting in the cytoplasm to reduce canonical NF-κB activation.
Aufstellung von Reisekosten und Ausgaben für Bücher während des Studienaufenthaltes in Bourges
Creators: name: Amerbach, Basilius
Publisher: name: [s.n.]
Year: 1557

description: Basilius Amerbach
description: Blätter 82a und 82b sind leer.
description: Kauf 1661 Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Mai 2015 Hans Berner
Material chemistry and surface reactivity during cyclic ozone exposures
Creators: name: Wade, Michael Owen
name: 0000-0003-0753-5676
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Ozone
Indoor materials

description: Ozone is a naturally occurring atmospheric gas with the ability to enter and be generated indoors. The indoor environment accounts for 25-60% of ozone inhalation. Lung function can be affected when people are exposed to ozone. In addition, when ozone enters the indoor environment it reacts with material surfaces and can affect the product life and function of these materials. Materials can also be chosen for the ability to remove ozone. This study focused first on ozone aging of material surfaces. Clay paint and ceiling tile were observed to be more reactive with ozone compared to particleboard and latex paint. The material ranking in order of highest to lowest reactivity were ceiling tile, clay paint, latex paint, and particleboard. These materials were exposed to air with and without ozone, with the goal to study the effect of diurnal oscillation of ozone in an indoor environment. Indoor ozone concentration oscillation can be driven either by variation in outdoor ozone concentration or by intermittent operation of the ventilation systems that bring outdoor ozone into the indoor environment. Over prolonged exposure to ozone the surface reactivity decreases, while a period without ozone exposure often allows “regeneration” of material reactivity. Laboratory experiments showed that after 18 hours of no ozone exposure, clay paint, ceiling tile, particleboard, and latex paint exhibited some regeneration. Materials with the lowest reactivity, latex paint and particleboard, showed the largest percent decrease in reactivity during ozone exposure, and the most samples with regeneration. Follow-up experiments, involving field aging of clay and latex-painted surfaces (without surface deposition), shows that ozone-driven surface reactivity decreases over a two year period. However, placement of samples for three months in a residential kitchen (with surface deposition) leads to increased ozone reactivity, lasting multiple exposures. When the clay paint and latex paint were exposed to ozone the gas-phase compound profile between the paints differed. Indicating that secondary emissions exposures would differ based on the specific paint. The paints were found to not only differ in ozone removal and byproducts, but also in the estimated toxicity of the byproducts. The gas-phase results help provide understanding to the decomposition of dried paints, degree of unsaturation during ozonolysis, and the original ingredients. This dissertation highlights the diversity of indoor material behavior during ozone-driven chemistry for four common indoor materials.
Abrechnungen über eingegangene Zinsen und Ausgaben für Handwerkerlöhne
Creators: name: Amerbach, Basilius
Publisher: name: [s.n.]
Year: 1562

description: Haushaltsbuch
description: Basilius Amerbach
description: Kauf 1661 Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Aus der Werkstatt der Amerbach-Edition / Ueli Dill, Beat Rudolf Jenny. - Basel : Schwabe, 2000. - S. 333-425
description: Verzeichnung=Description=Inventaire Mai 2015 Hans Berner
Electrical-transport characteristics of as-grown and oxygen-reduced La$_{0.7}$Ce$_{0.3}$MnO$_3$ films: calculation of hopping energies, Mn valences, and carrier localization lengths
Creators: name: Thiessen, Andreas
name: Beyreuther, Elke
name: Werner, Robert
name: Kleiner, Reinhold
name: Koelle, Dieter
name: Eng, Lukas M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Presently, cerium-doped LaMnO$_3$ is vividly discussed as an electron-doped counterpart prototype to the well-established hole-doped mixed-valence manganites. Here, La$_{0.7}$Ce$_{0.3}$MnO$_3$ thin films of different thicknesses, degrees of CeO$_2$ phase segregation, and oxygen deficiency, grown on SrTiO$_3$ single crystal substrates, are compared with respect to their resistance-vs.-temperature (R vs. T) behavior from 300~K down to 90~K. While the variation of the film thickness (and thus the degree of epitaxial strain) in the range between 10~nm and 100~nm has only a weak impact on the electrical transport, the degree of oxygen deficiency as well as the existence of CeO$_2$ clusters can completely change the type of hopping mechanism. This is shown by fitting the respective \textit{R-T} curves with three different transport models (adiabatic polaron hopping, Mott variable-range hopping, Efros-Shklovskii variable-range hopping), which are commonly used for the mixed-valence manganites. Several characteristic transport parameters, such as the hopping energies, the carrier localization lengths, as well as the Mn valences are derived from the fitting procedures.
description: 9 pages, 3 figures
Addressing Systematics in the Traceback Age of the $β$ Pictoris Moving Group
Creators: name: Couture, Dominic
name: Gagné, Jonathan
name: Doyon, René
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We characterize the impact of several sources of systematic errors on the computation of the traceback age of the $β$ Pictoris Moving Group ($β$PMG). We find that uncorrected gravitational redshift and convective blueshift bias absolute radial velocity measurements by $\sim$ 0.6 kms${}^{-1}$, which leads to erroneously younger traceback ages by $\sim$ 2 Myr. Random errors on parallax, proper motion, and radial velocity measurements lead to an additional bias of $\sim$ 1.5 Myr on traceback ages. Contamination of astrometric and kinematic data by kinematic outliers and unresolved multiple systems in the full input sample of 76 members and candidates of $β$PMG also erroneously lowers traceback ages by ${\sim}$ 3 Myr. We apply our new numerical traceback analysis tool to a core sample of 25 carefully vetted members of $β$PMG using Gaia Data Release 3 (DR3) data products and other kinematic surveys. Our method yields a corrected age of 20.4 $\pm$ 2.5 Myr, bridging the gap between kinematic ages (11$-$19 Myr) and other age-dating methods, such as isochrones and lithium depletion boundary (20$-$26 Myr). We explore several association size metrics that can track the spatial extent of $β$PMG over time, and we determine that minimizing the variance along the heliocentric curvilinear coordinate $ξ^{\prime}$ (i.e., toward the Galactic Center) offers the least random and systematic errors, due to the wider UVW space velocity dispersion of members of $β$PMG along the U-axis, which tends to maximize the spatial growth of the association along the $ξ^{\prime}$-axis over time.
Bücherliste
Libri non ligati
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1555
Subjects: Amerbach, Basilius1533-1591BasiliusAmerbach

description: Enthält hauptsächlich italienische Werke
description: Kauf 1661 Öffentliche Bibliothek der Universität Basel
description: Lateinisch
description: Verzeichnung=Description=Inventaire Mai 2015 Hans Berner
Interprofessional near-peer mentoring teams offer a sustainable approach for enhancing cancer research training of historically underrepresented students
Creators: name: Sipelii, Motu
name: Braley, Amanda
name: Shugerman, Susan R.
name: Shannon, Jackilen
name: Marriott, Lisa
Publisher: name: Oregon Health and Science University
Year: 2023
Subjects: subject: Mentoring
subject: Disabled Persons
subject: Workforce
subject: Vulnerable Populations
subject: Educational research methods and models
subject: Assessment of learning
subject: Underserved Populations

description: Mentorship is frequently included in biomedical research training plans, typically involving a combination of faculty, staff, and/or near-peers. Peer mentors serve as liaisons to programs and institutions, creating robust feedback loops that can inform programmatic areas for growth and identify inequities that may exist within training structures, thereby improving universal design of biomedical workforce training.
Machine learning detects multiplicity of the first stars in stellar archaeology data
Creators: name: Hartwig, Tilman
name: Ishigaki, Miho N.
name: Kobayashi, Chiaki
name: Tominaga, Nozomu
name: Nomoto, Ken'ichi
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In unveiling the nature of the first stars, the main astronomical clue is the elemental compositions of the second generation of stars, observed as extremely metal-poor (EMP) stars, in our Milky Way Galaxy. However, no observational constraint was available on their multiplicity, which is crucial for understanding early phases of galaxy formation. We develop a new data-driven method to classify observed EMP stars into mono- or multi-enriched stars with Support Vector Machines. We also use our own nucleosynthesis yields of core-collapse supernovae with mixing-fallback that can explain many of observed EMP stars. Our method predicts, for the first time, that $31.8\% \pm 2.3\%$ of 462 analyzed EMP stars are classified as mono-enriched. This means that the majority of EMP stars are likely multi-enriched, suggesting that the first stars were born in small clusters. Lower metallicity stars are more likely to be enriched by a single supernova, most of which have high carbon enhancement. We also find that Fe, Mg. Ca, and C are the most informative elements for this classification. In addition, oxygen is very informative despite its low observability. Our data-driven method sheds a new light on solving the mystery of the first stars from the complex data set of Galactic archaeology surveys.
description: Accepted by ApJ, main results in Fig. 5, source code is available at https://gitlab.com/thartwig/emu-c
Ausgaben für die Reise nach Speyer
Creators: name: Amerbach, Basilius
Publisher: name: [s.n.]
Year: 1560

description: Reisekosten
description: Basilius Amerbach
description: Kauf 1661 Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Mai 2015 Hans Berner
APASS Landolt-Sloan BVgri photometry of RAVE stars. I. Data, effective temperatures and reddenings
Creators: name: Munari, U.
name: Henden, A.
name: Frigo, A.
name: Zwitter, T.
name: Bienayme, O.
name: Bland-Hawthorn, J.
name: Boeche, C.
name: Freeman, K. C.
name: Gilmore, G.
name: Gibson, B. K.
name: Grebel, E. K.
name: Helmi, A.
name: Kordopatis, G.
name: Levine, S. E.
name: Navarro, J. F.
name: Parker, Q. A.
name: Reid, W.
name: Seabroke, G. M.
name: Siebert, A.
name: Siviero, A.
name: Smith, T. C.
name: Steinmetz, M.
name: Templeton, M.
name: Terrell, D.
name: Welch, D. L.
name: Williams, M.
name: Wyse, R. F. G.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We provide APASS photometry in the Landolt BV and Sloan g'r'i' bands for all the 425,743 stars included in the latest 4th RAVE Data Release. The internal accuracy of the APASS photometry of RAVE stars, expressed as error of the mean of data obtained and separately calibrated over a median of 4 distinct observing epochs and distributed between 2009 and 2013, is 0.013, 0.012, 0.012, 0.014 and 0.021 mag for B, V, g', r' and i' band, respectively. The equally high external accuracy of APASS photometry has been verified on secondary Landolt and Sloan photometric standard stars not involved in the APASS calibration process, and on a large body of literature data on field and cluster stars, confirming the absence of offsets and trends. Compared with the Carlsberg Meridian Catalog (CMC-15), APASS astrometry of RAVE stars is accurate to a median value of 0.098 arcsec. Brightness distribution functions for the RAVE stars have been derived in all bands. APASS photometry of RAVE stars, augmented by 2MASS JHK infrared data, has been chi2 fitted to a densely populated synthetic photometric library designed to widely explore in temperature, surface gravity, metallicity and reddening. Resulting Teff and E(B-V), computed over a range of options, are provided and discussed, and will be kept updated in response to future APASS and RAVE data releases. In the process it is found that the reddening caused by an homogeneous slab of dust, extending for 140 pc on either side of the Galactic plane and responsible for E(B-V,poles)=0.036 +/- 0.002 at the galactic poles, is a suitable approximation of the actual reddening encountered at Galactic latitudes |b|>=25 deg.
description: Astronomical Journal, in press. Resolution of Figures degrated to match arXiv file size limits
The Venus' Cloud Discontinuity in 2022
Creators: name: Peralta, J.
name: Cidadão, A.
name: Morrone, L.
name: Foster, C.
name: Bullock, M.
name: Young, E. F.
name: Garate-Lopez, I.
name: Sánchez-Lavega, A.
name: Horinouchi, T.
name: Imamura, T.
name: Kardasis, E.
name: Yamazaki, A.
name: Watanabe, S.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: First identified in 2016 by JAXA's Akatsuki mission, the discontinuity/disruption is a recurrent wave observed to propagate during decades at the deeper clouds of Venus (47--56 km above the surface), while its absence at the clouds' top ($\sim$70 km) suggests that it dissipates at the upper clouds and contributes in the maintenance of the puzzling atmospheric superrotation of Venus through wave-mean flow interaction. Taking advantage of the campaign of ground-based observations undertaken in coordination with the Akatsuki mission since December 2021 until July 2022, we aimed to undertake the longest uninterrupted monitoring of the cloud discontinuity up to date to obtain a pioneering long-term characterization of its main properties and better constrain its recurrence and lifetime. The dayside upper, middle and nightside lower clouds were studied with images with suitable filters acquired by Akatsuki/UVI, amateur observers and NASA's IRTF/SpeX, respectively. Hundreds of images were inspected in search of manifestations of the discontinuity events and to measure key properties like its dimensions, orientation or rotation period. We succeeded in tracking the discontinuity at the middle clouds during 109 days without interruption. The discontinuity exhibited properties nearly identical to measurements in 2016 and 2020, with an orientation of $91^{\circ}\pm 8^{\circ}$, length/width of $4100\pm 800$ / $500\pm 100$ km and a rotation period of $5.11\pm 0.09$ days. Ultraviolet images during 13-14 June 2022 suggest that the discontinuity may have manifested at the top of the clouds during $\sim$21 hours as a result of an altitude change in the critical level for this wave due to slower zonal winds.
description: 8 pages, 4 figures, 2 animated figures, 1 table
Dekanatsrechnung vom Juni 1588 bis Juni 1589
Creators: name: Amerbach, Basilius
Publisher: name: [s.n.]
Year: 1588

description: Universität
description: Basilius Amerbach
description: Kauf 1661 Öffentliche Bibliothek der Universität Basel
description: Lateinisch
description: Verzeichnung=Description=Inventaire Mai 2015 Hans Berner
All-in/all-out magnetic domains: X-ray diffraction imaging and magnetic field control
Creators: name: Tardif, Samuel
name: Takeshita, Soshi
name: Ohsumi, Hiroyuki
name: Yamaura, Jun-ichi
name: Okuyama, Daisuke
name: Hiroi, Zenji
name: Takata, Masaki
name: Arima, Taka-hisa
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Long-range non-collinear all-in/all-out magnetic order has been directly observed for the first time in real space in the pyrochlore Cd$_2$Os$_2$O$_7$ using resonant magnetic microdiffraction at the Os L$_3$ edge. Two different antiferromagnetic domains related by time-reversal symmetry could be distinguished and have been mapped within the same single crystal. The two types of domains are akin to magnetic twins and were expected - yet unobserved so far - in the all-in/all-out model. Even though the magnetic domains are antiferromagnetic, we show that their distribution can be controlled using a magnetic field-cooling procedure.
description: Main text: 11 pages, 4 figures ; Supplementary materials: 9 pages, 5 figures
Diverse Abrechnungen
Creators: name: Amerbach, Basilius
Publisher: name: [s.n.]
Year: 1578

description: Basilius Amerbach
description: Kauf 1661 Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Aus der Werkstatt der Amerbach-Edition / Ueli Dill, Beat Rudolf Jenny. - Basel : Schwabe, 2000. - S. 333-425
description: Verzeichnung=Description=Inventaire Mai 2015 Hans Berner
The ELIXIR training platform All Hands Meeting 2023
Creators: name: Alloza, Eva
name: Lindvall, Jessica
name: Heil, Katharina F
name: Manthos Pitoulias
name: Psomopoulos, Fotis
Publisher: name: F1000 Research Limited
Year: 2023

description: Presenting high-level developments of the ELIXIR Training Platform during the past year.
Pressure-induced phase transition and superconductivity in YBa2Cu4O8
Creators: name: Souliou, S. M.
name: Subedi, A.
name: Song, Y. T.
name: Lin, C. T.
name: Syassen, K.
name: Keimer, B.
name: Tacon, M. Le
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate the pressure and temperature dependence of the lattice dynamics of the underdoped, stoichiometric, high temperature superconductor YBa2Cu4O8 by means of Raman spectroscopy and ab initio calculations. This system undergoes a reversible pressure-induced structural phase transition around 10 GPa to a collapsed orthorhombic structure, that is well reproduced by the calculation. The coupling of the B1g-like buckling phonon mode to the electronic continuum is used to probe superconductivity. In the low pressure phase, self-energy effects through the superconducting transition renormalize this phonon, and the amplitude of this renormalization strongly increases with pressure. Whereas our calculation indicates that this mode's coupling to the electronic system is only marginally affected by the structural phase transition, the aforementioned renormalization is completely suppressed in the high pressure phase, demonstrating that under hydrostatic pressures higher than 10 GPa, superconductivity in YBa2Cu4O8 is greatly weakened or obliterated.
description: 6 pages, 4 figures. Accepted for publication in Phys. Rev. B (Rapid Com.). Supplemental Material available on demand
Cytokine Induction of Tumor Necrosis Factor Receptor 2 Is Mediated by STAT3 in Colon Cancer Cells
Creators: name: Hamilton, K. E.
name: Simmons, J. G.
name: Van Landeghem, L.
name: Lund, P. K.
name: Ding, S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The IL-6/STAT3 and TNFα/NFκB pathways are emerging as critical mediators of inflammation-associated colon cancer. TNFR2 expression is increased in inflammatory bowel diseases, the azoxymethane/dextran sodium sulfate (AOM/DSS) model of colitis-associated cancer, and by combined IL-6 and TNFα. The molecular mechanisms that regulate TNFR2 remain undefined. This study used colon cancer cell lines to test the hypothesis that IL-6 and TNFα induce TNFR2 via STAT3 and/or NFκB. Basal and IL-6 + TNFα-induced TNFR2 were decreased by pharmacological STAT3 inhibition. NFκB inhibition had little effect on IL-6 + TNFα-induced TNFR2, but did inhibit induction of endogenous IL-6 and TNFR2 in cells treated with TNFα alone. Chromatin immunoprecipitation (ChIP) revealed cooperative effects of IL-6 + TNFα to induce STAT3 binding to a -1578 STAT response element in the TNFR2 promoter, but no effect on NFκB binding to consensus sites. Constitutively active STAT3 was sufficient to induce TNFR2 expression. Over-expression of SOCS3, a cytokine-inducible STAT3 inhibitor, which reduces tumorigenesis in preclinical models of colitis-associated cancer, decreased cytokine-induced TNFR2 expression and STAT3 binding to the -1578 STAT response element. SOCS3 over-expression also decreased proliferation of colon cancer cells and dramatically decreased anchorage-independent growth of colon cancer cells, even cells over-expressing TNFR2. Collectively, these studies demonstrate that IL-6 and TNFα-induced TNFR2 expression in colon cancer cells is mediated primarily by STAT3, and provide evidence that TNFR2 may contribute to the tumor-promoting roles of STAT3.
Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Creators: name: Roman-Perez, E.
name: Rein, J.
name: Troester, M. A.
name: Harrell, J. C.
name: Stewart, D. A.
name: Camp, J. T.
name: Elloumi, F.
name: Perou, C. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Basal-like breast cancers have several well-characterized distinguishing molecular features, but most of these are features of the cancer cells themselves. The unique stromal-epithelial interactions, and more generally, microenvironmental features of Basal-like breast cancers have not been well characterized. To identify characteristic microenvironment features of Basal-like breast cancer we performed cocultures of several Basal-like breast cancer cell lines with fibroblasts and compared these to cocultures of Luminal breast cancer cell lines with fibroblasts. Interactions between Basal-like cancer cells and fibroblasts induced expression of numerous interleukins and chemokines, including IL-6, IL-8, CXCL1, CXCL3, and TGFbeta. Under the influence of fibroblasts, Basal-like breast cancer cell lines also showed increased migration in vitro. Migration was less pronounced for Luminal lines, but these lines were more likely to have altered proliferation. These differences were relevant to tumor biology in vivo, as the gene set that distinguished Luminal and Basal-like stromal interactions in coculture also distinguishes Basal-like from Luminal tumors with 98% accuracy in 10-fold CV and 100% accuracy in an independent test set. However, comparisons between cocultures where cells were in direct contact and cocultures where interaction was solely through soluble factors suggest that there is an important impact of direct cell-to-cell contact. The phenotypes and gene expression changes invoked by cancer cell interactions with fibroblasts support the microenvironment and cell-cell interactions as intrinsic features of breast cancer subtypes.
Investigation of Entrepreneurial Marketing Practices in Social Enterprises in the Context of Bangladesh
Creators: name: Parvin, Asma
Publisher: name: London South Bank University
Year: 2022

description: Despite the strong integration between marketing and entrepreneurship in practice and increasing attention towards social entrepreneurship (SE), marketing scholarsclaim that the current SE conceptualisation has yet satisfactorily offered a comprehensive framework for research, policy and practice adjoining its marketing phenomenon. This study thus employs entrepreneurial marketing (EM) as a theoretical framework to analyse and develop an insight into the practices used by social enterprises. As social enterprises typically seek betterment of social, environmental, and community-based initiatives and gain, the EM strategy often fits well for this venture as more unconventional means of marketing are usually required for such enterprises. In particular, this research investigates how social enterprises apply EM in Bangladesh, an emerging economy. In Bangladesh, Social Enterprises (SE) have experienced many challenges, including achieving long-term growth and remaining in business due to their unsustainable business models and lack of competitiveness in a highly competitive global market. A qualitative case study has been in this thesis adopts approach to examine the EM strategy and its practices. Data was also gathered and analysed through secondary sources such as online observation by reviewing websites, Facebook, YouTube, and different reports from case study SEs. In line with the interpretive approach, this online observation and case study method allows the researcher to gain insight into EM practices that helps the development of a new framework. Further, data was collected from interviews with the entrepreneurs and respective managers from some selected case study SEs. The researcher used a combination of purposive and snowballing sampling to determine 14 participants (entrepreneurs and managers) from seven case study SEs for in-depth interviews. Data triangulation was conducted to ensure the authenticity of data and information through in-depth interviewing of an additional five social entrepreneurs from five different SEs. By examining EM within the context of the social entrepreneurship sector, this study investigates how SEs in an emerging economy apply EM strategy. In so doing, this research examines the elements essential to an EM framework when being applied to a SE context. Furthermore, it offers a clear explanation of the interactivity of the elements. The thesis contributes to the EM literature by proposing a new EM framework for SEs, responding to the scholarly inquiry of cross-disciplinary research. A key contribution of this thesis lies in the integration of the social value creation element, an important aspect discussed in Shaw (2004) and Santos (2012), into the new EM framework and expanding this concept by introducing the empowerment dimension. In addition to the theoretical contributions, the research also offers managerial implications and suggestions for future studies
The provision of research inputs to the management of toxic blue-green algae
Creators: name: Mitchell, David S
Publisher: name: La Trobe
Year: 2023

description: Murray-Darling Freshwater Research Centre

MDFRC item.

The sustainable management of water resources to minimise problems with an ecological basis, such as blooms of blue-green algae, requires food understanding of the ecological background to the problem and the continuing input of appropriate research. Blooms of blue-green algae are primarily caused by excessive availability of nutrients, particularly phosphorus, though other factors such as temperature, light, river flow and grazing of animals can have effects. Blue-green algae are well adapted to monopolise good growth conditions and to dominate such blooms. Under certain conditions, toxins of two types, neurotoxins and hepatotoxins, are produced by blue-green algae. Research is required to refine understanding of all these issues. A comparison of the responses of Australia, southern Africa, the United Kingdom and North America to the occurrence of blue-green algal problems in their respective countries shows that the Australian response was somewhat cumbersome, and not well based on existing knowledge. However, it appears to have been effective. Early involvement of scientific societies such as the Australian Institute of Biology is advocated as a means of providing objective expert input at the earliest stages of developing an appropriate approach to such problems.
Basal-like Breast Cancer Cells Induce Phenotypic and Genomic Changes in Macrophages
Creators: name: Yang, Yinmeng
name: Troester, Melissa A.
name: Makowski, Liza
name: Stewart, Delisha A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Basal-like breast cancer (BBC) is an aggressive subtype of breast cancer that has no biologically-targeted therapy. The interactions of BBCs with stromal cells are important determinants of tumor biology, with inflammatory cells playing well-recognized roles in cancer progression. Despite the fact that macrophage-BBC communication is bidirectional, important questions remain about how BBCs affect adjacent immune cells. This study investigated monocyte-to-macrophage differentiation and polarization, and gene expression in response to coculture with basal-like versus luminal breast cancer cells. Changes induced by coculture were compared to changes observed under classical differentiation and polarization conditions. Monocytes (THP-1 cells) exposed to BBC cells in coculture had altered gene expression with upregulation of both M1 and M2 macrophage markers. Two sets of M1 and M2 markers were selected from the PCR profiles and used for dual immunofluorescence staining of BBC versus luminal cocultured THP-1s, and cancer-adjacent, benign tissue sections from patients diagnosed with BBC or luminal breast cancer confirming the differential expression patterns. Relative to luminal breast cancers, BBCs also increased differentiation of monocytes to macrophages and stimulated macrophage migration. Consistent with these changes in cellular phenotype, a distinct pattern of cytokine secretion was evident in macrophage-BBC cocultures, including upregulation of NAP-2, Osteoprotegerin, MIG, MCP-1, MCP-3 and IL-1β. Application of IL-1 receptor antagonist (IL-1RA) to cocultures attenuated BBC-induced macrophage migration. These data contribute to an understanding of the BBC-mediated activation of the stromal immune response, implicating specific cytokines that are differentially expressed in basal-like microenvironments and suggesting plausible targets for modulating immune responses to BBC.
State of the Science: An Update on Renal Cell Carcinoma
Creators: name: Rathmell, W. K.
name: Rini, B. I.
name: Bailey, S. T.
name: Brugarolas, J.
name: Futreal, P. A.
name: Sharma, P.
name: Walker, C. L.
name: Pause, A.
name: Atkins, M. B.
name: Davis, I. J.
name: Kim, W. Y.
name: Zurita, A. J.
name: Giaccia, A. J.
name: Jonasch, E.
name: Kurban, G.
name: Frydman, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Renal cell carcinomas (RCC) are emerging as a complex set of diseases with major socioeconomic impact and a continued rise in incidence throughout the world. As the field of urologic oncology faces these trends, several major genomic and mechanistic discoveries have altered our core understanding of this multitude of cancers, including several new rare subtypes of renal cancers. This review will examine these new findings, and place them in the context of the well-established association of clear cell RCC (ccRCC) with mutations in the von Hippel-Lindau (VHL) gene and resultant aberrant hypoxia inducible factor (HIF) signaling. The impact of novel ccRCC-associated genetic lesions on chromatin remodeling and epigenetic regulation is explored. The effects of VHL mutation on primary ciliary function, extracellular matrix homeostasis, and tumor metabolism are discussed. VHL proteostasis is reviewed, with the goal of harnessing the proteostatic machinery to refunctionalize mutant VHL. Translational efforts using molecular tools to understand discriminating features of ccRCC tumors and develop improved prognostic and predictive algorithms are presented and new therapeutics arising from the earliest molecular discoveries in ccRCC are summarized. By creating an integrated review of the key genomic and molecular biological disease characteristics of ccRCC and placing these data in the context of the evolving therapeutic landscape, we intend to facilitate interaction between basic, translational and clinical researchers involved in the treatment of this devastating disease, and accelerate progress towards its ultimate eradication.
Demographics of Protoplanetary Disks: A Simulated Population of Edge-on Systems
Creators: name: Angelo, Isabel
name: Duchêne, Gaspard
name: Stapelfeldt, Karl
name: Telkamp, Zoie
name: Ménard, Francoise
name: Padgett, Deborah
name: van der Plas, Gerrit
name: Villenave, Marion
name: Pinte, Christophe
name: Wolff, Schuyler
name: Fischer, William J.
name: Perrin, Marshall D.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The structure of protoplanetary disks plays an essential role in planet formation. Disks that are highly inclined, or ''edge-on'', are of particular interest since their geometry provides a unique opportunity to study the disk's vertical structure and radial extent. Candidate edge-on protoplanetary disks are typically identified via their unique spectral energy distribution and subsequently confirmed through high-resolution imaging. However, this selection process is likely biased toward the largest, most massive disks, and the resulting sample may not accurately represent the underlying disk population. To investigate this, we generated a grid of protoplanetary disk models using radiative transfer simulations and determined which sets of disk parameters produce edge-on systems that could be recovered by aforementioned detection techniques--i.e., identified by their spectral energy distribution and confirmed through follow-up imaging with HST. In doing so, we adopt a quantitative working definition of "edge-on disks" that is observation-driven and agnostic about the disk inclination or other properties. Folding in empirical disk demographics, we predict an occurrence rate of 6.2% for edge-on disks and quantify biases towards highly inclined, massive disks. We also find that edge-on disks are under-represented in samples of Spitzer-studied young stellar objects, particularly for disks with M $\lesssim$ 0.5 $M_\odot$. Overall, our analysis suggests that several dozen edge-on disks remain undiscovered in nearby star-forming regions, and provides a universal selection process to identify edge-on disks for consistent, population-level demographic studies.
description: 20 pages, 6 figures