cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Instabilities in the transient response of muscle
Creators: name: Vilfan, Andrej
name: Duke, Thomas
Publisher: name: arXiv
Year: 2003
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Quantitative Biology (q-bio)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: We investigate the isometric transient response of muscle using a quantitative stochastic model of the actomyosin cycle based on the swinging lever-arm hypothesis. We first consider a single pair of filaments, and show that when values of parameters such as the lever-arm displacement and the crossbridge elasticity are chosen to provide effective energy transduction, the T2 curve (the tension recovered immediately after a step displacement) displays a region of negative slope. If filament compliance and the discrete nature of the binding sites are taken into account, the negative slope is diminished, but not eliminated. This implies that there is an instability in the dynamics of individual half-sarcomeres. However, when the symmetric nature of whole sarcomeres is taken into account, filament rearrangement becomes important during the transient: as tension is recovered, some half-sarcomeres lengthen while others shorten. This leads to a flat T2 curve, as observed experimentally. In addition, we investigate the isotonic transient response and show that for a range of parameter values the model displays damped oscillations, as recently observed in experiments on single muscle fibers. We conclude that it is essential to consider the collective dynamics of many sarcomeres, rather than the dynamics of a single pair of filaments, when interpreting the transient response of muscle.
description: 11 pages, 11 figures, Submitted to Biophysical Journal
Particle Production in the Interiors of Acoustic Black Holes
Creators: name: Balbinot, Roberto
name: Fabbri, Alessandro
name: Dudley, Richard A.
name: Anderson, Paul R.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Gases (cond-mat.quant-gas)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Phonon creation inside the horizons of acoustic black holes is investigated using two simple toy models. It is shown that, unlike what occurs in the exterior regions, the spectrum is not thermal. This non-thermality is due to the anomalous scattering that occurs in the interior regions.
description: 28 pages, 17 figures
The atopic dermatitis itch scale: development of a new measure to assess pruritus in patients with atopic dermatitis
Creators: name: Martin, Susan A.
name: T. Michelle Brown
name: Fehnel, Sheri
name: Deal, Linda S.
name: Katz, Eva G.
name: Chiun-Fang Chiou
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Introduction: Pruritus is the primary symptom of atopic dermatitis (AD). The objective of this study was to develop a patient-reported outcome (PRO) instrument for daily administration in clinical trials to measure AD-related itch in adolescents and adults that would meet the standards described in the US Food and Drug Administration’s (FDA’s) PRO Guidance. Materials and methods: Six focus groups were conducted with 49 patients with AD (32 adults; 17 adolescents). Three iterative rounds of cognitive debriefing interviews were conducted in 26 patients with AD (17 adults; 9 adolescents) to pretest and refine the instrument. Results: AD-related itching was considered the most bothersome AD symptom by nearly two-thirds of the focus group participants. The items in the initial version of the instrument, named the Atopic Dermatitis Itch Scale (ADIS), were developed to reflect concepts most relevant to the assessment of itching as described during the focus groups. Based on results of the cognitive debriefing interviews, an 8-item final version of the ADIS was created. Conclusion: The ADIS is a content valid PRO instrument addressing the concepts critical to the measurement of AD-related itching. To our knowledge, it is the first instrument developed to assess AD-related itch in patients as young as 12 years following the recommendations of the PRO Guidance.
A question database for the German Longitudinal Election Study
Creators: name: Zenk-Moeltgen, Wolfgang
Publisher: name: Zenodo
Year: 2014

description: The GLES Question Database contains all the questions from the German Longitudinal Election Study (http://www.gesis.org/en/elections-home/gles/). The GLES Study is a large and ambitious election study in Germany. It is structured in eleven components conducted in different modes which are connected by a common core questionnaire. The GLES Question Database enables users to search for questions and is currently used as an internal tool for the GLES project. A public release is planned until summer 2014. Questions are shown with their answer categories, their variables, and their association to studies, along with some basic study level information. Studies may also be compared to see differences in methodology and topics covered. The GLES Question Database is a first product based on the STARDAT development that was shown at IASSIST before. It is based on DDI-Lifecycle re-usable components that build a basic common infrastructure for several applications. The GLES documentation was imported from a project specific database into DDI-Lifecycle format and combined with study level information from the GESIS Data Archive. The presentation will show challenges and solutions of the development of the GLES Question Database and the possibilities to use it for similar data collection projects.
Impact of memory-burdened primordial black holes on high-scale leptogenesis
Creators: name: Calabrese, Roberta
name: Chianese, Marco
name: Saviano, Ninetta
Publisher: name: arXiv
Year: 2025
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We explore the impact of the back-reaction of evaporation on the quantum state of Primordial Black Holes (PBHs), known as ``memory burden", on the baryon asymmetry production in the Universe through high-scale leptogenesis. Focusing on PBH masses ranging from 1 to 1000 grams, we investigate the interplay between the non-thermal production of heavy sterile neutrinos and the entropy injection within this non-standard cosmological framework. By assuming appropriate values for the memory-burden parameters, $q=1/2$ and $k=1$, we derive mutual exclusion limits between PBHs and thermal leptogenesis in the mixed parameter space. Our analysis reveals that the primary contribution of PBHs to baryon asymmetry stems from entropy injection. Indeed, we find that, differently from earlier studies based on the semi-classical Hawking evaporation, the memory-burden effect suppresses the non-thermal source term in the PBH mass range explored. This has significant implications for understanding baryogenesis in such alternative cosmological scenarios.
description: 10 pages, 4 figures
Wave turbulence on the surface of a fluid in a high-gravity environment
Creators: name: Cazaubiel, Annette
name: Mawet, Sébastien
name: Darras, Alexis
name: Grosjean, Galien
name: van Loon, Jack
name: Dorbolo, Stéphane
name: Falcon, Eric
Publisher: name: arXiv
Year: 2019
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Chaotic Dynamics (nlin.CD)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: We report on the observation of gravity-capillary wave turbulence on the surface of a fluid in a high-gravity environment. By using a large-diameter centrifuge, the effective gravity acceleration is tuned up to 20 times the Earth gravity. The transition frequency between the gravity and capillary regimes is thus increased up to one decade as predicted theoretically. A frequency power-law wave spectrum is observed in each regime and is found to be independent of the gravity level and of the wave steepness. While the timescale separation required by weak turbulence is well verified experimentally regardless of the gravity level, the nonlinear and dissipation timescales are found to be independent of the scale, as a result of the finite size effects of the system (large-scale container modes) that are not taken currently into account theoretically.
description: in press
Developing data literacies for graduate students in the social sciences
Creators: name: Mooney, Hailey
name: Carlson, Jake
Publisher: name: Zenodo
Year: 2014

description: What competencies in working with data do graduate students in the Social Sciences need to acquire before they graduate? What roles can librarians and other information professionals play in teaching these competencies to graduate students? This paper will report on preliminary findings from an investigation into the data management competencies and skill gaps of graduate students in the social sciences. Building from the work of the Data Information Literacy (DIL) project (http://datainfolit.org), this study uses an interview-based approach to discern how competencies in working with data are understood and valued by graduate students and their faculty advisors. The DIL project identified and employed 12 data competencies as starting points for interviews and for developing educational programming on data literacies for graduate students. As the original DIL project focused on students in five different STEM fields, this extended study into the social sciences (DIL-SS) will allow for comparisons of perceptions and practices between these disciplines. In addition, DIL-SS presents an opportunity to further develop the 12 DIL competencies and test their relevance to educational needs in the social sciences. Our findings will inform the work of librarians and others involved in offering data management education and consulting services in academic settings.
Ectropis excursaria Guenee
Creators: name: Young, Catherine J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Geometridae
Ectropis
Ectropis excursaria

description: Ectropis excursaria Guenée (Figs 493–500)
Oviposition
6♀ code nos.: G12, G41, G50, G62, G287, G437
Oviposition period: 26 Mar.–12 Oct.
Batch size: 47.2 ± 8.8 range: 6–100 (n = 11)
Mean realised fecundity: 86.5 ± 24.4 (range): 30–173
Incubation time (days): 18–29
 Batch configuration and attachment: Loosely attached, singly or large groups (Figs 493–495)); sometimes inserted into folds of paper. In nature, poked into narrow crevices such as in bark (McFarland 1988).
 Colour: Light yellowish­green, becoming rust­brown starting at anterior pole, greyish brown on maturity (Figs 493 & 494).
 Size (mm): (n=10) L =0.73 ± 0.01, W =0.44 ± 0.01, T = 0.40 ± 0.01
Width/length: 0.60
No. of females: 1
 Aeropylar opening size (m) (n=5): L=1.1 ± 0.10.
Relative aeropylar opening size: 1.4
 Micropyles: Distinct (Figs 496 & 497)
No. of openings: 4
No. of cells in rosette: 6
No. of rows of cells in micropylar area: 4
 Shape: Very narrow, elongated, bluntly ovoid, anterior pole truncated; flattened dorsoventrally (Figs 493–496, 498).
 Characteristics: Chorion soft. Egg distinctly marked on all surfaces by concave quadrate cells with moderately broad, rounded walls, arranged in longitudinal rows (Figs 495, 496 & 498). Aeropyles elevated, domed, openings very small (Fig. 499), present on all surfaces apart from middle of top of egg (Figs 496 & 498). Primary, secondary cells in micropylar area recessed (Fig. 497). Chorion heavily blistered, appearing granular (Figs 499 & 500).
description: Published as part of Young, Catherine J., 2006, Descriptions of the eggs of some southern Australian Geometridae (Lepidoptera), pp. 1-294 in Zootaxa 1287 on pages 1-294
Exploring the potential of Halalkalibacterium halodurans laccase for endosulfan and chlorophacinone degradation: insights from molecular docking and molecular dynamics simulations
Creators: name: Pant, Rajat
name: Kumar, Ravi
name: Sharma, Shilpa
name: Karuppasamy, Ramanathan
name: Veerappapillai, Shanthi
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Pesticides are widely used in agriculture but at the same time, a majority of them are known to cause serious harm to health and the environment. In the recent past, laccases have been reported as key enzymes having the ability to degrade pollutants by converting them into less toxic forms. In this investigation, laccase from polyextremophilic bacterium Halalkalibacterium halodurans C-125 was analyzed for its structural, physicochemical, and functional characterization using in silico approaches. The 3D model of the said enzyme is unknown; therefore, the model was generated by template-independent modeling using ROBETTA, I-TASSER, and Alphafold server. The best-generated model from Alphafold with a confidence of 0.95 was validated from ERRAT and Verify 3D scores of 89.95 and 91.80%, respectively. The Ramachandran plot generated using the PROCHECK server further predicted the accuracy of the model with 93.7% and 5.9% of residues present in most favored and additional allowed regions of the plot respectively. The active sites, ion binding sites, and subcellular localization of laccase were also predicted. The generated model was docked with 121 pollutants (pesticides, insecticides, herbicides, fungicides, and rodenticides) for its degradation potential towards these pollutants. Two ligands chlorophacinone (based on the highest binding energy) and endosulfan (based on agricultural uses) were selected for molecular dynamic simulation studies. Endosulfan as a pesticide is banned but in some countries governments allow its use for special purposes which need serious consideration on developing bioremediation approaches for endosulfan degradation. MD simulation studies revealed that both chlorophacinone and endosulfan form hydrogen bonds and hydrophobic bonds with the active site of laccase and chlorophacinone-laccase complex were more stable in comparison to endosulfan. The present investigation provides insight into the structural features of laccase and its potential for the degradation of pesticides which can be further validated by experimental data.
title: Athena
title: Städtisches Möbelkonzept
titleType: Subtitle
Creators: name: Moosmann, Lukas
Publisher: name: FH Vorarlberg (Fachhochschule Vorarlberg)
Year: 2021
Subjects: subject: 700 Künste und Unterhaltung

description: Im postdigitalen Zeitalter, in dem wir uns befinden, ist ein gesellschaftlicher Wandel erkennbar. Die Arbeitswelt verlangt zunehmend nach Flexibilität und dynamischen Prozessen. Es herrscht ein allgemeines Selbstverständnis bezüglich der Einschätzung, dass digitale Technologien in unserem Alltag als fester Bestandteil integriert sind. Als Gegenpol zu den digitalen Netzwerken herrscht ein starkes Bedürfnis nach analogen Erlebnissen. Öffentliche Arenen eignen sich seit jeher als Orte der Begegnung. Verantwortliche in Städten und Betreiber von Gewerbeparks beschäftigen sich mit der Frage, wie sie Areale aufwerten und den Nutzern ein attraktives Angebot schaffen können. Die vorliegende Arbeit beschäftigt sich mit den Bedürfnissen der Nutzer (Stadtbewohner/-besucher) in Bezug auf städtische Möbelkonzepte. Leitmotiv ist, durch unterschiedliche Methoden einen besseren Einblick in urbane Räume und das Spannungsfeld zwischen Mensch, Ort und Möbel zu bekommen. Ein besonderer Schwerpunkt liegt auf der fotodokumentarischen Studie von vorhandenen Möbelkonzepten. Ziel ist es, Arealverantwortlichen sowie Gestaltern Möglichkeiten für zukünftige urbane Möbelkonzepte aufzuzeigen.
description: In the post-digital age in which we currently live, a societal change is evident. Nowadays, the working world increasingly demands flexibility and dynamic processes. Furthermore, it is considered inevitable that digital technologies have become a crucial part in our everyday life. Nevertheless, as a counterpoint to digital networks, there exists a strong urge for real experiences. As a matter of fact, particularly, public arenas have throughout history been suitable places for such specific social encounters. Therefore, those people, who are responsible in cities and industrial parks, are dealing with the question of how they can upgrade certain areas and create an attractive surrounding for their users. As a result, the present paper deals with the users’ needs, referring to city’s inhabitants and its visitors, in relation to urban furniture concepts. The objective of this thesis is to gain a deeper insight into urban spaces and focusing on the interaction between people, place, and furniture by applying different methods. In addition, there will be a special focus on a photo-documentary study of existing furniture concepts. However, the overall aim of this paper is to show and provide possibilities for future urban furniture concepts, which might be useful and of great interest to area managers as well as to designers.
Nurturing biophilia : home economics in the elementary classroom
Creators: name: Mohn, Camille
Publisher: name: The University of British Columbia
Year: 2023

description: This paper documents my teacher action research, during which I explored ways to foster biophilia in elementary school, through home economics and the metaphor of earth as home. I began with a literature review, examining biophilia and how it is already apparent in education. I used this foundation as a jumping off point to plan learning experiences for my students, implement them, observe and reflect on my teaching practice. In this paper I share my experience and what I learned as I infused biophilia into my elementary class through home economics. Home economics is not taught as a separate subject at the elementary level but home economics concepts, particularly food studies, can be integrated using the theme “the world is our home” and using the natural environment to foster biophilia and sustainable living.
Irrealism from fringe visibility in matter-wave double-slit interference with initial contractive states
Creators: name: Lustosa, F. R.
name: Dieguez, P. R.
name: da Paz, I. G.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The elements of reality coined by Einstein, Podoslky, and Rosen promoted a series of fundamental discussions involving the notion of quantum correlations and physical realism. The superposition principle applied in the double-slit experiment with matter waves highlights the need for a critical review of the adoption of physical realism in the quantum realm. In this work, we employ a measure of physical irrealism and consider an initial contractive state in the double-slit setup for which position and momentum variables of a single particle are initially correlated. We investigate how the behavior of the irrealism can help us to obtain information about the interference pattern, wavelike, and particle-like properties in the double-slit setup with matter waves. We find that there is a time of propagation that minimizes the irrealism, and around this point the state at the detection screen is squeezed in position and momentum in comparison with the standard Gaussian superposition. Interestingly, we show that the maximum visibility and the number of interference fringes are related to the minimum of the irrealism. Moreover, we demonstrate a monotonic relation between the irrealism and visibility around the time of minimum. Then, we argue how to use these results to indirectly measure the irrealism for position variable from the fringe visibility.
description: 12 pages, 7 figures, typos removed, closer to the published version
Mass-symmetry breaking in three-body ions
Creators: name: Korobov, V. I.
name: Richard, J. -M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The ground-state energy of three-body ions $(M^+,M^+,m^-)$ evolves when the like-charge constituents are given different masses. The comparison of $(m_1^+,m_2^+,m^-)$ with the average of $(m_1^+,m_1^+,m^-)$ and $(m_2^+,m_2^+,m^-)$ reveals a competition between the symmetric term and the antisymmetric one. The former dominates in the Born--Oppenheimer regime such as the (p,t,e) case, while the latter wins for H$^-$-like systems with two negative light particles surrounding a heavy nucleus. A comparison is also made with the case of baryons in simple quark models with flavour independence.
description: 4 pages, 3 figures
Lipegfilgrastim: pharmacodynamics and pharmacokinetics for body-weight-adjusted and 6 mg fixed doses in two randomized studies in healthy volunteers
Creators: name: Buchner, Anton
name: Lammerich, Andreas
name: Abdolzade-Bavil, Afsaneh
name: Müller, Udo
name: Bias, Peter
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: Two phase I, single-blind (subject blinded to treatment), randomized studies were conducted to assess the pharmacodynamics, pharmacokinetics, safety, and tolerability of lipegfilgrastim compared with pegfilgrastim in healthy adult volunteers. Study 1 consisted of a pilot safety phase (N = 8) during which subjects received a single body-weight-adjusted subcutaneous dose of lipegfilgrastim 25 µg/kg and a dose escalation phase (N = 45) wherein subjects received lipegfilgrastim 50 or 100 μg/kg or pegfilgrastim 100 μg/kg. Study 2 was a single-blind, fixed-dose study (N = 36) comparing subcutaneous lipegfilgrastim 6 mg and pegfilgrastim 6 mg. Cumulative exposure (AUC0–tlast and AUC0–∞) and peak exposure (Cmax) were higher for lipegfilgrastim than pegfilgrastim after both weight-adjusted and fixed dosing. In both studies, the terminal elimination half-life of lipegfilgrastim was 5–10 hours longer than the terminal elimination half-life for pegfilgrastim at the maximum dose, and the time to maximum serum concentration (tmax) was observed later for lipegfilgrastim than for pegfilgrastim. The area over the baseline effect curve (AOBEC) for absolute neutrophil count (ANC) was approximately 30% greater after lipegfilgrastim dosing compared with the same dose of pegfilgrastim at the maximum dose. Both drugs were well tolerated, with a similar occurrence of adverse events between treatment groups. Key limitations of these studies include the small numbers of subjects and differences in dosage regimens between the two studies. In these studies, lipegfilgrastim provided a longer-lasting increase in ANC compared with pegfilgrastim at an equivalent dose, without increasing the peak ANC values. This may reflect the higher cumulative exposure and slower clearance (therefore longer body residence) of lipegfilgrastim. These data support the use of single-dose lipegfilgrastim 6 mg in subsequent phase III trials as prophylactic treatment for patients receiving myelosuppressive chemotherapy.
The infrared spectrum of protonated buckminsterfullerene, C60H+
Creators: name: Palotás, Julianna
name: Martens, Jonathan
name: Berden, Giel
name: Oomens, Jos
Publisher: name: arXiv
Year: 2019
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: Although fullerenes have long been hypothesized to occur in interstellar environments, their actual unambiguous spectroscopic identification is of more recent date. C60, C70 and C60+ now constitute the largest molecular species individually identified in the interstellar medium (ISM). Fullerenes have significant proton affinities and it was suggested that C60H+ is likely the most abundant interstellar analogue of C60. We present here the first laboratory infrared (IR) spectrum of gaseous C60H+. Symmetry breaking relative to C60 produces an IR spectrum that is much richer than that of C60. The experimental spectrum is used to benchmark theoretical spectra indicating that the B3LYP density functional with the 6-311+G(d,p) basis set accurately reproduces the spectrum. Comparison with IR emission spectra from two planetary nebulae, SMP LMC56 and SMC16, that have been associated with high C60 abundances, indicate that C60H+ is a plausible contributor to their IR emission.
description: 9 pages, 4 figures
Creating catalog records that reflect data use restrictions
Creators: name: Hayslett, Michele
name: Henley, Amanda
name: Gunther, Wanda
name: Yarborough, Margaretta
name: Collins, Joe
Publisher: name: Zenodo
Year: 2014

description: Many researchers don't realize the restrictions involved in using licensed data for research. The Data Services staff at UNC – Chapel Hill are working with catalogers to present that information within our catalog records to give the opportunity for that information to be discovered in advance of deciding on a given data set, better aligning the research and data infrastructures. This session will discuss this collaborative effort, the specific MARC fields we're using and implications for sustainability and for outreach (to increase visibility).
Questasy, a DDI based data dissemination tool
Creators: name: De Vet, Edwin
Publisher: name: Zenodo
Year: 2014

description: Questasy is a data dissemination tool based on DDI3 developed at CentERdata. It is written in CakePHP and uses a MySQL database. It supports documentation of longitudinal studies as well as the creation of custom datasets. OAI-PMH support for harvesting of studies can be easily set up. The metadata of studies can be exported as DDI 3.1 XML (since version 4.2). Since CakePHP is an MVC framework and supports theming, Questasy can be easily modified to meet specific customer needs. Version 5.0 saw two main features implemented: multilingual support and DDI 3.1 import. For future developments we will investigate whether we can implement DDI 3.2 export and import. Further issues that will be implemented are better documentation of questionnaire routing, summary statistics of variables and dissemination of datasets and syntax created by researchers.
Mini-Optics Solar Energy Concentrator
Creators: name: Davidson, Mark
name: Rabinowitz, Mario
Publisher: name: arXiv
Year: 2003
Subjects: subject: General Physics (physics.gen-ph)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: This invention deals with the broad general concept for focussing light. A mini-optics tracking and focussing system is presented for solar power conversion that ranges from an individual's portable system to solar conversion of electrical power that can be used in large scale power plants for environmentally clean energy. It can be rolled up, transported, and attached to existing man-made, or natural structures. It allows the solar energy conversion system to be low in capital cost and inexpensive to install as it can be attached to existing structures since it does not require the construction of a superstructure of its own. This novel system is uniquely distinct and different from other solar tracking and focussing processes allowing it to be more economical and practical. Furthermore, in its capacity as a power producer, it can be utilized with far greater safety, simplicity, economy, and efficiency in the conversion of solar energy.
description: 16 pages, 12 figures, 2 tables
Testing the Mechanism of R-parity Breaking with Slepton LSP Decays
Creators: name: Bartl, A.
name: Hirsch, M.
name: Kernreiter, T.
name: Porod, W.
name: Valle, J. W. F.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In supersymmetric models R-parity can be violated through either bilinear or trilinear terms in the superpotential, or both. If charged scalar leptons are the lightest supersymmetric particles, their decay properties can be used to obtain information about the relative importance of these couplings. We show that in some specific scenarios it is even possible to decide whether bilinear or trilinear terms give the dominant contribution to the neutrino mass matrix.
description: Intro rewritten, Fig 1 and Fig 4 slightly changed, conclusions unchanged, 25 pages, 4 figures
Interaction between concentric Tubes in DWCNTs
Creators: name: Pfeiffer, R.
name: Kramberger, Ch.
name: Simon, F.
name: Kuzmany, H.
name: Popov, V. N.
name: Kataura, H.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A detailed investigation of the Raman response of the inner tube radial breathing modes (RBMs) in double-wall carbon nanotubes is reported. It revealed that the number of observed RBMs is two to three times larger than the number of possible tubes in the studied frequency range. This unexpected increase in Raman lines is attributed to a splitting of the inner tube response. It is shown to originate from the possibility that one type of inner tube may form in different types of outer tubes and the fact that the inner tube RBM frequency depends on the diameter of the enclosing tube. Finally, a comparison of the inner tube RBMs and the RBMs of tubes in bundles gave clear evidence that the interaction in a bundle is stronger than the interaction between inner and outer tubes.
description: 6 pages, 7 figures, submitted to Eur. Phys. J. B
Assessment of the safety and efficacy of extended-release oxycodone/acetaminophen, for 14 days postsurgery
Creators: name: Singla, Neil
name: Barrett, Thomas
name: Sisk, Lisa
name: Kostenbader, Kenneth
name: Young, Jim
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: To investigate the safety and satisfaction of patients treated ≤14 days after unilateral bunionectomy with extended-release oxycodone/acetaminophen (ER OC/APAP), a biphasic (ER and immediate release) fixed-dose combination analgesic being developed for moderate to severe acute pain. This was an open-label extension (OLE) of a randomized, double-blind, placebo-controlled trial (DBRCT) of patients undergoing bunionectomy. Patients who consented to the OLE before entering the 48 hour DBRCT entered the OLE upon completing the DBRCT and during the OLE received two tablets of ER OC/APAP (15/650 mg total dose) every 12 hours for ≤14 days. ClinicalTrials.gov identifier: NCT01484652. Treatment-emergent adverse events, physical examinations, vital sign measurements, and clinical laboratory testing were assessed throughout the study. Global assessments of treatment satisfaction were made at the end of the DBRCT and at each clinic visit during the OLE. A total of 146 patients consented to the OLE before entering the DBRCT and 129 completed the OLE. Tolerability of ER OC/APAP during the OLE was consistent with that of an opioid product. Adverse events occurred during the OLE in 64 patients (43.8%); the most common were gastrointestinal events including nausea (17.8%), vomiting (7.5%), and constipation (6.2%). No changes in vital signs or clinical laboratory tests were considered by the investigator to be clinically significant. At all visits during the OLE, the majority of patients were satisfied or very satisfied with their medication. Limitations include a 14 day postprocedure study duration that may be confounded with natural healing time, and lack of a placebo arm. These results show that ER OC/APAP demonstrated an expected safety and tolerability profile and good patient satisfaction in a postsurgical model of acute pain.
Linking health data with social science data
Creators: name: Nielsen, Amalie
Publisher: name: Zenodo
Year: 2014

description: Archiving, dissemination and reuse of research data enhance the opportunities to make secondary analyses on new subjects. By using the DDI-Lifecycle standard you can make meta-analyses and comparative analyses on data materials from different research areas. In the Danish Data Archive we archive and disseminate health data as well as data from the social sciences. By linking those kinds of data we can get new forms of knowledge on the social impact on public health. Danish Data Archive facilitate the use of registries and databases from the health care system and other administrative resources, along with health surveys and the possibility to link it to classic social surveys like surveys of cultural habits. The different kind of data material makes the comparison complicated. Data has been collected by different researchers and institutions for different purposes. The DDI-Lifecycle standardized metadata and comprehensive study descriptions are the key to make linking and comparison possible.
Linking Vibrational Dynamics to Local Electronic Structure: Local Analysis of Dynamics of the relaxed Si$_{87}$ Cluster
Creators: name: Liu, Lei
name: Jayanthi, C. S.
name: Wu, Shi-Yu
Publisher: name: arXiv
Year: 2003
Subjects: subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: A flexible scheme for decomposing the vibrational density of states in terms of pair vibrational density of states is presented. This scheme provides the linkage between the site vibrational density of states and pair vibrational density of states so that vibrational modes, in particular localized modes, can be conveniently examined in terms of the correlation between the vibration at a given site and those at its neighboring sites. Furthermore, within the framework of a total energy vibrational spectrum study, this scheme allows the analysis of vibrational modes in terms of their electronic origin. A case study of the vibrational dynamics of the relaxed Si$_{87}$ cluster is carried out to demonstrate the flexibility of the scheme in analyzing the properties of vibrational modes, particularly for complex systems with reduced or no symmetry.
description: 4 pages, 8 figures
Collective inertial masses in nuclear reactions
Creators: name: Wen, Kai
name: Nakatsukasa, Takashi
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Towards the microscopic theoretical description for large amplitude collective dynamics, we calculate the coefficients of inertial masses for low-energy nuclear reactions. Under the scheme of energy density functional, we apply the adiabatic self-consistent collective coordinate (ASCC) method, as well as the Inglis' cranking formula to calculate the inertias for the translational and the relative motions, in addition to those for the rotational motion. Taking the scattering between two $α$ particles as an example, we investigate the impact of the time-odd components of the mean-field potential on the collective inertial masses. The ASCC method asymptotically reproduces the exact masses for both the relative and translational motions. On the other hand, the cranking formula fails to do so when the time-odd components exist.
description: 8 pages, 9 figures
An open-label multicenter study to assess the safety of dextromethorphan/quinidine in patients with pseudobulbar affect associated with a range of underlying neurological conditions
Creators: name: Pattee, Gary L.
name: Wymer, James P.
name: Lomen-Hoerth, Catherine
name: Appel, Stanley H.
name: Formella, Andrea E.
name: Pope, Laura E.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Pseudobulbar affect (PBA) is associated with neurological disorders or injury affecting the brain, and characterized by frequent, uncontrollable episodes of crying and/or laughing that are exaggerated or unrelated to the patient’s emotional state. Clinical trials establishing dextromethorphan and quinidine (DM/Q) as PBA treatment were conducted in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS). This trial evaluated DM/Q safety in patients with PBA secondary to any neurological condition affecting the brain. To evaluate the safety and tolerability of DM/Q during long-term administration to patients with PBA associated with multiple neurological conditions. Fifty-two-week open-label study of DM/Q 30/30 mg twice daily. Safety measures included adverse events (AEs), laboratory tests, electrocardiograms (ECGs), vital signs, and physical examinations. #NCT00056524. A total of 553 PBA patients with >30 different neurological conditions enrolled; 296 (53.5%) completed. The most frequently reported treatment-related AEs (TRAEs) were nausea (11.8%), dizziness (10.5%), headache (9.9%), somnolence (7.2%), fatigue (7.1%), diarrhea (6.5%), and dry mouth (5.1%). TRAEs were mostly mild/moderate, generally transient, and consistent with previous controlled trials. Serious AEs (SAEs) were reported in 126 patients (22.8%), including 47 deaths, mostly due to ALS progression and respiratory failure. No SAEs were deemed related to DM/Q treatment by investigators. ECG results suggested no clinically meaningful effect of DM/Q on myocardial repolarization. Differences in AEs across neurological disease groups appeared consistent with the known morbidity of the primary neurological conditions. Study interpretation is limited by the small size of some disease groups, the lack of a specific efficacy measure and the use of a DM/Q dose higher than the eventually approved dose. DM/Q was generally well tolerated over this 52 week trial in patients with PBA associated with a wide range of neurological conditions.
Phelotis cognata Walker
Creators: name: Young, Catherine J.
Publisher: name: Zenodo
Year: 2006
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Geometridae
Phelotis
Phelotis cognata

description: Phelotis cognata Walker (Figs 514–522)
(type species)
Oviposition
3♀ code nos.: G4, G44, G61
Oviposition period: 14 Mar.–23 Apr.
Batch size: 20.8 ± 5.9 range: 8–40 (n = 5)
Realised fecundity (range): 8–85
Incubation time (days): 15
 Batch configuration and attachment: Loosely attached, singly (Fig. 514).
 Colour: Pale olive green, becoming rusty brown from anterior pole, grey on maturity (Fig. 514).
 Size (mm): (n=1) L = 0.51, W = 0.36, T = 0.29
Width/length: 0.70
No. of females: 1
 Aeropylar opening size (m) (n = 4): L = 1.34 ± 0.10, W = 0.93 ± 0.10.
Relative aeropylar opening size: 2.6
 Micropyles: Distinct (Figs 516 & 517)
No. of openings: obscure
No. of cells in rosette: 7
No. of rows of cells in micropylar area: 3
 Shape: Narrow, elongated, bluntly ovoid, anterior pole truncated; flattened dorsoventrally; elongated (Figs 514–516, 518).
 Characteristics: Chorion soft. Egg distinctly marked on all surfaces by concave, elongate, quadrate cells with moderately broad, rounded, elevated walls, arranged in longitudinal rows (Figs 514–516, 518–521), anterior cell walls narrowly reticulated (Fig. 517). Aeropyles elevated, openings moderately large (Figs 520 & 521), present only on, around anterior pole (Fig. 520). Rosette cells recessed (Fig. 517). Chorion generally smooth, but sparsely blistered (Figs 519, 520 & 522); ridged on anterior pole cells (Fig. 521).
description: Published as part of Young, Catherine J., 2006, Descriptions of the eggs of some southern Australian Geometridae (Lepidoptera), pp. 1-294 in Zootaxa 1287 on pages 1-294
Aggregation and cytotoxicity of food additive dye (Azorubine)-albumin adducts: a multi-spectroscopic, microscopic and computational analysis
Creators: name: Khan, Mohd Shahnawaz
name: Rehman, Md Tabish
name: Shaik, Gouse M.
name: Alamri, Abdulaziz Mohammed
name: AlAjmi, Mohamed F.
name: Arshad, Mohammed
name: Alokail, Majed S.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Molecular Biology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Protein and peptide misfolding is a central factor in the formation of pathological aggregates and fibrils linked to disorders like Alzheimer’s and Parkinson’s diseases. Therefore, it’s essential to understand how food additives, particularly Azorubine, affect protein structures and their ability to induce aggregation. In this study, human serum albumin (HSA) was used as a model protein to investigate the binding and conformational changes caused by azorubine, a common food and drink colorant. The research revealed that azorubine destabilized the conformation of HSA at both physiological (pH 7.4) and acidic (pH 3.5) conditions. The loss of tryptophan fluorescence in HSA suggested significant structural alterations, particularly around aromatic residues. Far UV-CD analysis demonstrated disruptions in HSA's secondary structure, with a notable reduction in α-helical structures at pH 7.4. At pH 3.5, Azorubine induced even more extensive perturbations, resulting in a random coil conformation at higher azorubine concentrations. The study also investigated aggregation phenomena through turbidity measurements, RLS analysis, and TEM imaging. At pH 3.5, larger insoluble aggregates formed, while at pH 7.4, only conformational changes occurred without aggregate formation. Cytotoxicity assessments on neuroblastoma (SH-SY5Y) cells highlighted the concentration-dependent toxicity of albumin aggregates. Molecular dynamics simulations reaffirmed the stable interaction between azorubine and HSA. This research provides valuable insights into the mechanisms by which azorubine influences protein conformations. To further advance our understanding and contribute to the broader knowledge in this area, several future directions can be considered such as exploring other proteins, studying dose-response relationship, gaining mechanistic insights, biological relevance, toxicity assessment, identifying alternative food colorants, and mitigation strategies to prevent adverse effects of azorubine on serum proteins.
Stellar populations associated with the LMC Papillon Nebula
Creators: name: Meynadier, F.
name: Heydari-Malayeri, M.
name: Deharveng, L.
name: Charmandaris, V.
name: Bertre, Th. Le
name: Rosa, M. R.
name: Schaerer, D.
name: Zinnecker, H.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study the Large Magellanic Cloud Papillon Nebula (N159-5), a conspicuous High Excitation Blob (HEB) lying in the star forming complex N159. Using JHK near-infrared photometry obtained at the ESO VLT with the ISAAC camera, we examine the stellar populations associated with the Papillon, tracing their history using stellar evolution models. Two populations are revealed: one composed of young, massive stars with an age ~ 3 Myr, and a second consisting of older lower mass stars of age spreading between 1 and 10 Gyr. We analyze the properties of those populations and discuss their significance in the context of N159. We also estimate that if the star at the center of the Papillon is single its initial mass is ~ 50 solar masses and it is affected by an extinction Av ~ 7 mag.
description: Accepted in A&A 11 pages, 10 figures, 12 on-line material pages (= 1 table) Some figures have been replaced by jpeg versions to reduce the overall size
Fast optimization of parametrized quantum optical circuits
Creators: name: Miatto, Filippo M.
name: Quesada, Nicolás
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Parametrized quantum optical circuits are a class of quantum circuits in which the carriers of quantum information are photons and the gates are optical transformations. Classically optimizing these circuits is challenging due to the infinite dimensionality of the photon number vector space that is associated to each optical mode. Truncating the space dimension is unavoidable, and it can lead to incorrect results if the gates populate photon number states beyond the cutoff. To tackle this issue, we present an algorithm that is orders of magnitude faster than the current state of the art, to recursively compute the exact matrix elements of Gaussian operators and their gradient with respect to a parametrization. These operators, when augmented with a non-Gaussian transformation such as the Kerr gate, achieve universal quantum computation. Our approach brings two advantages: first, by computing the matrix elements of Gaussian operators directly, we don't need to construct them by combining several other operators; second, we can use any variant of the gradient descent algorithm by plugging our gradients into an automatic differentiation framework such as TensorFlow or PyTorch. Our results will find applications in quantum optical hardware research, quantum machine learning, optical data processing, device discovery and device design.
description: 21 pages, 10 figures