cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Synthesis and functionalisation of highly substituted oxetanes: molecular scaffolds for drug discovery
Creators: name: Davis, Owen Alexander
Publisher: name: Imperial College London
Year: 2016

description: This thesis details new approaches to the synthesis and functionalisation of highly substituted, diversely functionalised oxetanes (Scheme 1). These types of 2-substituted oxetanes constitute desirable 3-dimensional motifs for medicinal chemistry, which exhibit desirable physicochemical properties as fragment molecules and could be core scaffolds to be grown along multiple vectors. The first section presents an introduction to the methods of oxetane synthesis, drug discovery, the recent incorporation of oxetanes into drug discovery and other uses of oxetanes. Section 3 describes investigations into the derivatisation of the C=C double bond of novel 2-methyleneoxetanes. Section 4 then outlines the successful development of a rapid, efficient and functional group tolerant 2-step synthesis of 2,2-substituted oxetanes via a Rh(II)-catalysed O–H insertion and a C–C bond forming cyclisation utilising anion stabilising groups to stabilise the intermediate carbanion. This methodology initially employed diazo malonate derivatives and alcohols bearing leaving groups (-halohydrins) to access di, tri and tetrasubstituted oxetanes with a diverse range of functional groups. This was then expanded to incorporate a wider range of functionalised diazo compounds, including combinations of ester, amide, sulfone, phosphonate, nitrile and (hetero)aromatic substituents as anion stabilising groups (Section 5). These highly substituted oxetanes contained handles which underwent derivatisation to access diversely functionalised molecules. Finally, incorporation of the ketone moiety into this methodology led to a C–O bond forming cyclisation, forming 1,4-dioxenes (Section 6). In order to achieve high yields, a Ru(II)-catalysed O–H insertion was developed. Initial investigations into the derivatisation of these unusual partially saturated heterocycles were conducted to access functionalised 3-dimensional scaffolds potentially of interest in medicinal chemistry.
Influence of pre-weaning trace mineral exposure on subsequent performance and trace mineral status of beef calves during finishing
Creators: name: Neville, Bryan W.
name: Baumgaertner, Friederike
name: Pickinpaugh, Wayde J.
name: Menezes, Ana Clara B.
name: McCarthy, Kacie L.
name: Undi, Michael R.
name: Dahlen, Carl R.
Publisher: name: The Bovine Practitioner
Year: 2024
Subjects: beef calves
feedlot performance
liver
trace minerals

description: Objectives of these experiments were to 1) evaluate the accu­mulation of Co, Cu, Mn and Zn in liver tissue during the fin­ishing period of calves with or without previous mineral sup­plement exposure; and 2) evaluate the performance of calves provided either organic or inorganic sources of Co, Cu, Mn and Zn. One-hundred twenty steers of unknown mineral history, and 48 steers of known mineral history prior to weaning were comin­gled in experiment 1. Steers were allocated to pens and assigned to receive either an inorganic or organic trace minerals. For experiment 2, 83 steers with or without exposure to mineral supplements during gestation and the subsequent lactation, were utilized in a 181-d finishing experiment. ADG tended to be greater (P = 0.09) during the first 53 days on feed in calves provided organic trace minerals. Calves with trace mineral access prior to weaning were heavier at the time of feedlot arrival (P = 0.06), but not at slaughter (P = 0.37). Pro­viding access to mineral supplements to cow-calf pairs dur­ing grazing increased (P < 0.01) Cu and Co, but did not affect (P ≥ 0.29) Zn or Mn concentrations at feedlot arrival. Liver Cu status improved during backgrounding in steers fed the or­ganic trace minerals. For calves of known mineral history, providing access to mineral sup­plements during grazing, prior to weaning, had no impacts on subsequent gain or intake during growing and finishing. Providing organic forms of trace minerals tended to improve growth early in the feeding period.


 
description: The Bovine Practitioner, Vol. 58 No. 1 (2024): ONLINE FIRST
Adiabatic expansions for Dirac fields, renormalization, and anomalies
Creators: name: G., J. Fernando Barbero
name: Ferreiro, Antonio
name: Navarro-Salas, Jose
name: Villasenor, Eduardo J. S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We introduce an iterative method to univocally determine the adiabatic expansion of the modes of Dirac fields in spatially homogeneous external backgrounds. We overcome the ambiguities found in previous studies and use this new procedure to improve the adiabatic regularization/renormalization scheme. We provide details on the application of the method for Dirac fields living in a four-dimensional Friedmann-Lemaitre-Robertson-Walker spacetime with a Yukawa coupling to an external scalar field. We check the consistency of our proposal by working out the conformal anomaly. We also analyze a two-dimensional Dirac field in Minkowski space coupled to a homogeneous electric field and reproduce the known results on the axial anomaly. The adiabatic expansion of the modes given here can be used to properly characterize the allowed physical states of the Dirac fields in the above external backgrounds.
description: 10 pages. Revised version, misprints corrected, some points clarified
Bradypus tridactylus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Pilosa
Bradypodidae
Bradypus
Bradypus tridactylus

description: Bradypus tridactylus [spec. nov.]
B. manibus tridactylis, cauda brevi. Syst. nat. 6. p. 3. Amoen. acad. 1. p. 487. * Mus. Ad. Fr. 4.
Arctopithaecus. Gesn. quadr. 869. t. 870.
Ai s. Ignavus. Margr. bras. 221. Clus. exot. 110. t. 373. Seb. mus. 1. p. 53. t. 33. f. 2. Olear. mus. 7. t. 6. f. 2.
Habitat in Americae meridionalis arboribus; Victitat foliis teneris; non bibit; imbres metuit.
Gula flava. Auriculae nullae. Cauda subovata. Digiti combinati. Ungues palmarum 3; plantarum 3. Mammae 2 pectorales. Corpus valde pilosum, vitae tenax.
Facile scandit, tardissime & vix incedit, attonitus quasi caput flectit; sonus senarius adscendens; clamor horrendus, lacrimae miserae.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on pages 34-35, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Correlation function as a measure of the structure
Creators: name: Buryak, O.
name: Doroshkevich, A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Geometrical model of structure of the universe is examined to obtain analytical expression for the two points nonlinear correlation function. According to the model the objects (galaxies) are concentrated into two types of structure elements - filaments and sheets. We considered the filaments ( similar to galaxy filaments ) simply as straight lines and the sheets ( similar to superclusters of galaxies ) simply as planes. The homogeneously distributed objects are also taken into consideration. The spatial distribution of lines, planes and points is uncorrelated. The nonlinear correlation function depends on four parameters and is similar to the observed and simulated ones for different samples. It describes quite well the correlation of galaxies, clusters of galaxies and dark matter distribution. Possible interpretation of the parameters of nonlinear correlation function is discussed.
description: 8 pages, uucode
Additional file 2 of LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP
Creators: name: Hu, Lin
name: Wang, Jing
name: Wang, Yunliang
name: Wu, Linpeng
name: Wu, Chao
name: Mao, Bo
name: Maruthi Prasad, E.
name: Wang, Yuhong
name: Chin, Y. Eugene
Publisher: name: figshare
Year: 2020
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Chemical Sciences not elsewhere classified
Science Policy
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Cancer

description: Additional file 1: Figure S1. LOXL1 overexpression inhibits the proliferation of CRC cells. a HCT8-N/HCT8-LOXL1 and SW480-N/SW480-LOXL1 cells were detected by CCK8 analysis. Data are shown as the mean ± SD of triplicate independent sets of experiments; statistical significance was assessed by unpaired t-test. ***P < 0.001, ****P < 0.0001. b Apoptosis was analysed by 7AAD/Annexin-V labeling. Representative dot plots shown on the left, quantified for apoptosis on right. Data are shown as the mean ± SD of triplicate independent sets of experiments; statistical significance was assessed by unpaired t-test. ns; non-significant.
Thermal Critical Points and Quantum Critical End Point in the Frustrated Bilayer Heisenberg Antiferromagnet
Creators: name: Stapmanns, Jonas
name: Corboz, Philippe
name: Mila, Frederic
name: Honecker, Andreas
name: Normand, Bruce
name: Wessel, Stefan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We consider the finite-temperature phase diagram of the $S = 1/2$ frustrated Heisenberg bilayer. Although this two-dimensional system may show magnetic order only at zero temperature, we demonstrate the presence of a line of finite-temperature critical points related to the line of first-order transitions between the dimer-singlet and -triplet regimes. We show by high-precision quantum Monte Carlo simulations, which are sign-free in the fully frustrated limit, that this critical point is in the Ising universality class. At zero temperature, the continuous transition between the ordered bilayer and the dimer-singlet state terminates on the first-order line, giving a quantum critical end point, and we use tensor-network calculations to follow the first-order discontinuities in its vicinity.
description: 6 pages, 4 figures; supplemental material: 3 pages, 3 figures; v2: as published
Viable supplier selection problem based on Industry 5.0 and circular economy aspects: a hybrid decision-making approach
Creators: name: Nayeri, Sina
name: Sazvar, Zeinab
name: Tirkolaee, Erfan Babaee
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Space Science
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The importance of evaluating the supplier in today’s dynamic and competitive marketplace is undeniable. Therefore, in recent years, managers and researchers have been looking for various approaches to enhance the evaluation process of the suppliers. Therefore, this study addresses the Supplier Selection Problem (SSP) considering three crucial features namely the Circular Economy (CE), viability, and Industry 5.0 (I5.0) dimensions. Here, a novel decision-making model is developed to assess the suppliers’ performance. To do so, the stochastic fuzzy Best-Worst Method (BWM) is employed to calculate the indicator’s importance, and then, a modified approach named stochastic fuzzy Complex Proportional Assessment (COPRAS) is developed to complete the evaluation. Furthermore, the applicability of the suggested methodology is demonstrated by a real-world case study in the automotive industry. The obtained results reveal that ‘Responsiveness', ‘Robustness', ‘Reliability', ‘Cost', ‘Quality', ‘Waste Management’, ‘Greenhouse Gas (GHG) emissions', ‘Information systems', and ‘Job safety' are the most significant indicators of the research problem, whereas Suppliers A2 and A5 attain the most appropriate performance. Moreover, the sensitivity analysis and comparative evaluation between our methodology and the traditional ones prove its efficiency, robustness, and validity.
A Planetary Companion to the Nearby M4 Dwarf, Gliese 876
Creators: name: Marcy, G. W.
name: Butler, R. P.
name: Vogt, S. S.
name: Fischer, D. A.
name: Lissauer, J. J.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Doppler measurements of the M4 dwarf star, Gliese 876, taken at both Lick and Keck Observatory reveal periodic, Keplerian velocity variations with a period of 61 days. The orbital fit implies that the companion has a mass of, M = 2.1 MJUP /sin i, an orbital eccentricity of, e = 0.27+-0.03, and a semimajor axis of, a = 0.21 AU. The planet is the first found around an M dwarf, and was drawn from a survey of 24 such stars at Lick Observatory. It is the closest extrasolar planet yet found, providing opportunities for follow--up detection. The presence of a giant planet on a non-circular orbit, 0.2 AU from a 1/3 M_Sun star, presents a challenge to planet formation theory. This planet detection around an M dwarf suggests that giant planets are numerous in the Galaxy.
description: 13 pages, 3 Figures
Solid state processing of organic semiconducting polymer blends
Creators: name: Armgarth, Astrid
Publisher: name: Imperial College London
Year: 2017

description: Organic electronics is an exciting scientific frontier that holds great promise for the manufacture of low-cost, flexible electronic devices. The advancement of these technologies relies on gaining a deeper understanding of important structure/ processing/property interrelationships in organic semiconductors. Addressing such fundamental questions enables the employment of well-defined schemes to efficiently improve device performances and optimise industrially relevant processing routes. Compression molding, a solid state process, is for example an excellent candidate for the manufacture of mechanically robust, freestanding organic semiconductor films with a high degree of molecular order and anisotropy. Regrettably, research into the use of such promising processing means are to date sorely lacking, limiting their applicability for future commercialisations. This thesis explores the solid state processing of the model semiconductor poly(3-hexylthiophene) (P3HT) and several blends with thermoplastic insulators. Studies herein address key areas in which solid state pressing has not yet been optimised and demonstrate versatile schemes that facilitate enhanced microstructure formation, molecular ordering and charge transport pathways in the freestanding films. Investigations further verify for the first time the highly anisotropic charge transport properties (as determined by time-of-flight photoconductivity measurements) that arise from solid state processing. Moreover, these flexible films, with well-defined semiconducting architectures, are envisaged as outstanding candidates for the regeneration of electroresponsive biological tissues and as regenerative platforms. The solid state processing protocols are therefore augmented with facile patterning techniques to replicate biologically relevant surface topographies, in the form of microgrooves, onto the film surfaces. Preliminary cell studies, using a cardiac-like cell line, indicate that the substrates support cell culture practices, and that the cells aligned on the groove surfaces. The results presented herein thereby demonstrate that solid state processing of neat organic semiconductors and their blends is a versatile and facile avenue to generate highly structured semiconducting architectures with potential bioelectronic applications.
Dualities and 5-brane webs for 5d rank 2 SCFTs
Creators: name: Hayashi, Hirotaka
name: Kim, Sung-Soo
name: Lee, Kimyeong
name: Yagi, Futoshi
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider Type IIB 5-brane configurations for 5d rank 2 superconformal theories which are classified recently by geometry in arXiv:1801.04036. We propose all the 5-brane web diagrams for these rank 2 theories and show dualities between some of different gauge theories with explicit duality map of mass parameters and Coulomb branch moduli. In particular, we explicitly construct 5-brane configurations for $G_2$ gauge theory with six flavors and its dual $Sp(2)$ and $SU(3)$ gauge theories. We also present 5-brane webs for $SU(3)$ theories of Chern-Simons level greater than 5.
description: v1: 84 pages, v2: 89 pages, a subsection added and new diagrams added, published version
Az Al-Kaida térnyerése a Maghreb régióban
Creators: name: János, Besenyő
Publisher: name: figshare
Year: 2018
Subjects: subject: 160604 Defence Studies
subject: FOS: Political science
subject: 210310 Middle Eastern and African History
subject: FOS: History and archaeology

description: AQIM in Maghreb region
Negative Energy Modes and Gravitational Instability of Interpenetrating Fluids
Creators: name: Casti, A. R. R.
name: Morrison, P. J.
name: Spiegel, E. A.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study the longitudinal instabilities of two interpenetrating fluids interacting only through gravity. When one of the constituents is of relatively low density, it is possible to have a band of unstable wave numbers well separated from those involved in the usual Jeans instability. If the initial streaming is large enough, and there is no linear instability, the indefinite sign of the free energy has the possible consequence of explosive interactions between positive and negative energy modes in the nonlinear regime. The effect of dissipation on the negative energy modes is also examined.
description: 21 Latex pages, 4 postscript figures. To appear in Volume 867 of the Annals of the New York Academy of Sciences; typos and grammatical errors corrected
A New Perspective on the Large-Scale Tidal Effect on the Galaxy Luminosity and Morphology
Creators: name: Lee, Jounghun
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We study the mean tidal coherence of galaxy environments as a function of intrinsic luminosity determined by the absolute $r$-band magnitude. The tidal coherence of a galaxy environment is estimated as the cosine of the angle between two minor eigenvectors of the tidal field smoothed at the scales of $2$ and $30\,h^{-1}$Mpc centered on each of the local galaxies from the Sloan Digital Sky Data Release 10. Creating four luminosity-selected samples of the Sloan galaxies, we control them to have identical density distributions, in order to nullify the dominant effect of the local density. It is found that the samples containing more luminous wall and field galaxies yield lower mean values of the tidal coherence, which trend turns out to be robust against the variation of the smoothing scales. At fixed morphology, the same trend is found for the late-type spiral and lenticular galaxies in both of the field and wall environments. The early-type spiral field galaxies show no significant dependence on the tidal coherence, while both of the least and most luminous elliptical wall galaxies are found to dwell in the regions with highest tidal coherence.
description: accepted for publication in ApJ, 8 figures, 1 table, revised version, minor changes
Bradypus didactylus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Pilosa
Bradypodidae
Bradypus
Bradypus didactylus

description: Bradypus didactylus [spec. nov.]
B. manibus didactylis, cauda nulla. Syst. nat. 3. Mus. Ad. Fr. 4.
Tardigradus ceilanicus. Seb. mus. l. p. 54. t. 34. f. 1. & t. 33. f. 4.
Habitat in Zeylona.
Corpus pilis ferrugineis undulatis. Caput rotundatum. Auriculae magnae. Ungues in palmis 2, in plantis 3. Mammae 2 pectorales.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 35, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Measuring q_0 from the Distortion of Voids in Redshift Space
Creators: name: Ryden, Barbara
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Because the transformation from distance to redshift is nonlinear, maps in redshift space become increasingly distorted as the redshift z becomes greater. As noted by Alcock \& Paczyński (1979), observed redshift distortions can be used to estimate the deceleration parameter $q_0$. If $q_0$ is greater than -1, voids in redshift space will be elongated along the line of sight. In addition, distant voids will have a greater volume in redshift space than nearby voids. Accurate measurement of the volume and the axis ratio of voids, as a function of their central redshift, will provide an estimate of $q_0$. To test this method of estimating $q_0$, I create a two-dimensional toy universe, free of peculiar velocities, in which the galaxies are located near the walls of Voronoi cells. The galaxies are then mapped into redshift space, adopting different values of $q_0$. In redshift space, I estimate the area and the axis ratio of the voids by fitting ellipses within the voids, using an algorithm which maximizes the area of the empty ellipses and ensures that ellipses do not overlap. The accuracy of the estimated values of $q_0$ is limited by the intrinsic scatter in the size and shape of the voids. In the toy universe, distinguishing between a $q_0 = -1$ universe and a $q_0 = 1/2$ universe requires a survey which goes to a depth z > 0.1 in redshift space. Peculiar velocities will create an additional source of uncertainty for the values of $q_0$ measured in N-body simulations and in the real universe.
description: to appear in the ApJ. 14 pages uuencoded compressed postscript Seven figures available as a compressed tar file via ftp at ftp://bessel.mps.ohio-state.edu/pub/ryden/figs.tar.Z
Actual Physics behind Mono-X
Creators: name: Bernreuther, Elias
name: Horak, Jan
name: Plehn, Tilman
name: Butter, Anja
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Mono-X searches are standard dark matter search strategies at the LHC. First, we show how in the case of initial state radiation they essentially collapse to mono-jet searches. Second, we systematically study mono-X signatures from decays of heavier dark matter states. Direct detection constraints strongly limit our MSSM expectations, but largely vanish for mono-Z and mono-Higgs signals once we include light NMSSM mediators. Finally, the decay topology motivates mono-W-pair and mono-Higgs-pair searches, strengthening and complementing their mono-X counterparts.
description: 32 pages, 18 figures; version v2: corrected typos, added references; version v3: added figures and references, corrected typos
Under Pressure: The Application of Compression Garments for Exercise and Recovery in Athletes
Creators: name: Leabeater, Alana
Publisher: name: La Trobe
Year: 2025
Subjects: classificationCode: 4207
subject: Sports science and exercise
classificationCode: 420702
subject: Exercise physiology
classificationCode: 420109
subject: Rehabilitation

description: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Allied Health, Human Services and Sport, La Trobe University, Victoria, Australia.
The nuclear spectrum of the radio galaxy NGC 5128 (Centaurus A)
Creators: name: Simpson, Chris
name: Meadows, Vikki
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present near-infrared spectra of the nuclear disk in the nearby radio galaxy NGC 5128 (Centaurus A). On the basis of the observed strengths of the [S III] 0.9532um and [Fe II] 1.2567um lines, we classify NGC 5128 as a LINER. Modeling of the strengths of these and additional lines suggests that the nuclear region is powered by shocks rather than photoionization.
description: 12 pages including 2 figures, accepted by ApJ Letters
Rapid determination of Alternaria mycotoxins in tomato samples by pressurised liquid extraction coupled to liquid chromatography with fluorescence detection
Creators: name: Rico-Yuste, Alberto
name: Gómez-Arribas, Lidia N.
name: Pérez-Conde, María Concepción
name: Urraca, Javier L.
name: Moreno-Bondi, María Cruz
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: Plant Biology

description: A sensitive and reliable method using pressurised liquid extraction (PLE) followed by molecularly imprinted solid phase extraction (MISPE) and high performance liquid chromatography with fluorescence detection (HPLC–FLD) has been developed for the analysis of alternariol (AOH) and alternariol monomethyl ether (AME) in tomato samples. Influence of several extraction parameters that affect PLE efficiency were evaluated for the simultaneous extraction of both mycotoxins in the selected samples. AOH and AME were optimally extracted using MeOH/water (25:75, v/v) at 70°C as solvent, a pressure of 1000 psi and a single extraction cycle. The resulting PLE extracts were pre-concentrated by molecularly imprinted solid phase extraction (MISPE) cartridges followed of analysis by HPLC with fluorescence detection (λexc = 258, λem = 440 nm). The proposed method was applied to the analysis of AOH and AME in fortified tomato samples (20–72 µg· kg–1) with recoveries of 84–97% (RSD n = 6) for AOH and 67–91% (RSD n = 6) for AME. The detection limit for AOH and AME were 7 and 15 µg· kg–1, respectively. The ensuing PLE–MISPE–HPLC–FLD method was validated for the analysis of both mycotoxins in tomato samples in accordance with European Commission Decision 2002/657/EC.
NGTS-2b: An inflated hot-Jupiter transiting a bright F-dwarf
Creators: name: Raynard, Liam
name: Goad, Michael R.
name: Gillen, Edward
name: Nielsen, Louise D.
name: Watson, Christopher A.
name: Thompson, Andrew P. G.
name: McCormac, James
name: Bayliss, Daniel
name: Soto, Maritza
name: Csizmadia, Szilard
name: Chaushev, Alexander
name: Burleigh, Matthew R.
name: Alexander, Richard
name: Armstrong, David J.
name: Bouchy, François
name: Briegal, Joshua T.
name: Cabrera, Juan
name: Casewell, Sarah L.
name: Chazelas, Bruno
name: Cooke, Benjamin F.
name: Eigmüller, Philipp
name: Erikson, Anders
name: Gänsicke, Boris T.
name: Grange, Andrew
name: Günther, Maximilian N.
name: Hodgkin, Simon T.
name: Hooton, Matthew J.
name: Jenkins, James S.
name: Lambert, Gregory
name: Louden, Tom
name: Metrailler, Lionel
name: Moyano, Maximiliano
name: Pollacco, Don
name: Poppenhaeger, Katja
name: Queloz, Didier
name: Raddi, Roberto
name: Rauer, Heike
name: Read, Andrew M.
name: Smalley, Barry
name: Smith, Alexis M. S.
name: Turner, Oliver
name: Udry, Stéphane
name: Walker, Simon R.
name: West, Richard G.
name: Wheatley, Peter J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We report the discovery of NGTS-2b, an inflated hot-Jupiter transiting a bright F5V star (2MASS J14202949-3112074; $T_{\rm eff}$=$6478^{+94}_{-89}$ K), discovered as part of the Next Generation Transit Survey (NGTS). The planet is in a P=4.51 day orbit with mass $0.74^{+0.13}_{-0.12}$ M$_{J}$, radius $1.595^{+0.047}_{-0.045}$ R$_{J}$ and density $0.226^{+0.040}_{-0.038}$ g cm$^{-3}$; therefore one of the lowest density exoplanets currently known. With a relatively deep 1.0% transit around a bright V=10.96 host star, NGTS-2b is a prime target for probing giant planet composition via atmospheric transmission spectroscopy. The rapid rotation ($vsin$i=$15.2\pm0.8$ km s$^{-1}$) also makes this system an excellent candidate for Rossiter-McLaughlin follow-up observations, to measure the sky-projected stellar obliquity. NGTS-2b was confirmed without the need for follow-up photometry, due to the high precision of the NGTS photometry.
description: 12 pages, 8 figures, accepted for publication in MNRAS
Myrmecophaga Linnaeus, 1758, gen. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Pilosa
Myrmecophagidae
Myrmecophaga

description: Myrmecophaga [gen. nov.]
Dentes nulli.
Lingua teres, extensilis.
Corpus pilis tectum.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 35, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Additional file 6 of LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP
Creators: name: Hu, Lin
name: Wang, Jing
name: Wang, Yunliang
name: Wu, Linpeng
name: Wu, Chao
name: Mao, Bo
name: Maruthi Prasad, E.
name: Wang, Yuhong
name: Chin, Y. Eugene
Publisher: name: figshare
Year: 2020
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Chemical Sciences not elsewhere classified
Science Policy
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Cancer

description: Additional file 5: Figure S5. YAP can reverse the inhibitory effect of LOXL1. Transwell migration and Matrigel invasion assays were performed in LOXL1 alone or LOXL1 and YAP co-transfected HCT8 cells. Representative images (left panel) and quantification (right panel) are shown as indicated. Data from three independent experiments are presented as the mean ± SD. Statistical significance was assessed by unpaired t-test; **P < 0.01. Scale bar: 100 μm.
Social Vulnerability and Disparities in Perinatal Health for Victorian Women: Determining Gaps in Outcomes, Access, and Equity.
Creators: name: Faulks, Fiona
Publisher: name: La Trobe
Year: 2025
Subjects: classificationCode: 420321
subject: Rural and remote health services
classificationCode: 420403
subject: Psychosocial aspects of childbirth and perinatal mental health
classificationCode: 420503
subject: Community and primary care
classificationCode: 420402
subject: Models of care and place of birth
classificationCode: 420401
subject: Clinical midwifery
classificationCode: 440902
subject: Counselling, wellbeing and community services
classificationCode: 441012
subject: Sociology of inequalities
classificationCode: 441011
subject: Sociology of health

description: Submitted in total fulfillment of the requirements for the degree of Doctor of Philosophy to the School of Nursing and Midwifery, La Trobe University, Victoria, Australia.
Additional file 7 of LOXL1 modulates the malignant progression of colorectal cancer by inhibiting the transcriptional activity of YAP
Creators: name: Hu, Lin
name: Wang, Jing
name: Wang, Yunliang
name: Wu, Linpeng
name: Wu, Chao
name: Mao, Bo
name: Maruthi Prasad, E.
name: Wang, Yuhong
name: Chin, Y. Eugene
Publisher: name: figshare
Year: 2020
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Chemical Sciences not elsewhere classified
Science Policy
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Cancer

description: Additional file 6: Figure S6. a H-E staining of HCT8-N/HCT8-LOXL1 and SW480-N/SW480-LOXL1 xenograft tumours. b and c HCT8-N/HCT8-LOXL1 and SW480-N/SW480-LOXL1 xenograft tumours were detected the p-YAP(S127) and Ki67 levels by immunohistochemistry. d Cell apoptosis in xenografted tumors was measured by the TUNEL assay. Scale bar: 100 μm.
LOCAL INSTITUTIONAL LINKAGES IN FARMING SYSTEMS RESEARCH AND EXTENSION
Creators: name: Heinrich, G
name: Modiakgotla, E
name: Uquillas, J
name: Navas, B
name: Heinrich, G
name: Modiakgotla, E
name: Uquillas, J
name: Navas, B
Publisher: name: Unknown
Year: 1993
Subjects: Community/Rural/Urban Development

description: The purpose of this paper is to present an approach for improving local level linkages among research and extension institutions in Botswana. The approach is used to strengthen the impact of FSR specifically' and agricultural development in general. The primary linkage mechanism has been the Regional Coordinating Committee (RCC), an informal body composed of representatives from a wide range of agricultural development oriented institutions. The paper discusses how these committees function, and type of research-extension collaboration that have stemmed from their work. The RCCs have also improved government-NGO collaboration and coordination, and most importantly a more effective delivery of information and services to farmers. An important factor explaining the RCCs' success is their bottom-up approach to coordination, which stands in contrast with largely unsuccessful efforts to mandate coordination from the centre.
BindsNET: A machine learning-oriented spiking neural networks library in Python
Creators: name: Hazan, Hananel
name: Saunders, Daniel J.
name: Khan, Hassaan
name: Sanghavi, Darpan T.
name: Siegelmann, Hava T.
name: Kozma, Robert
Publisher: name: arXiv
Year: 2018
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: The development of spiking neural network simulation software is a critical component enabling the modeling of neural systems and the development of biologically inspired algorithms. Existing software frameworks support a wide range of neural functionality, software abstraction levels, and hardware devices, yet are typically not suitable for rapid prototyping or application to problems in the domain of machine learning. In this paper, we describe a new Python package for the simulation of spiking neural networks, specifically geared towards machine learning and reinforcement learning. Our software, called BindsNET, enables rapid building and simulation of spiking networks and features user-friendly, concise syntax. BindsNET is built on top of the PyTorch deep neural networks library, enabling fast CPU and GPU computation for large spiking networks. The BindsNET framework can be adjusted to meet the needs of other existing computing and hardware environments, e.g., TensorFlow. We also provide an interface into the OpenAI gym library, allowing for training and evaluation of spiking networks on reinforcement learning problems. We argue that this package facilitates the use of spiking networks for large-scale machine learning experimentation, and show some simple examples of how we envision BindsNET can be used in practice. BindsNET code is available at https://github.com/Hananel-Hazan/bindsnet
A ROSAT Search for X-ray Emission from Quasar Host Clusters
Creators: name: Hall, Patrick B.
name: Ellingson, Erica
name: Green, Richard F.
name: Yee, Howard
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the results of a search for X-ray emission from quasar host clusters at moderate redshift using the {\sl ROSAT} HRI. We detect no emission from the host clusters of 3C~263 (z=0.646) and PKS~2352-34 (z=0.706) to 3$σ$\ limits of 3.26 and 2.86 $\times$10$^{44}$\ ergs~s$^{-1}$ respectively (H$_o$=50, q$_o$=1/2) for clusters with r$_{core}$=125~kpc and T=5~keV. These limits show that these quasar host clusters are not substantially more X-ray luminous than optically or X-ray selected clusters of similar richnesses at z$\gtrsim$0.5. We also report the possible detection of a clump of X-ray emitting gas coincident with the brightest radio lobe of 3C~263. This may be evidence for the existence of a clumpy ICM in the host cluster of 3C~263.
description: Scheduled for the August 1995 Astronomical Journal; 21 pages including figures in uuencoded compressed PostScript format; also available from http://astro.as.arizona.edu/~pathall/preprints.html
Additional file 2 of Development of Chinese mental health first aid guidelines for psychosis: a Delphi expert consensus study
Creators: name: Li, Wenjing
name: Jorm, Anthony F.
name: Wang, Yan
name: Lu, Shurong
name: He, Yanling
name: Reavley, Nicola
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 2.
A Broader Approach to Common Resource Management: Landcare and Integrated Catchment Management in Queensland, Australia
Creators: name: Roberts, Kate
name: Coutts, Jeff
name: Roberts, Kate
name: Coutts, Jeff
Publisher: name: Unknown
Year: 1997
Subjects: Resource /Energy Economics and Policy

description: The purpose of the paper is to explore various definitions and assumptions about common resource management and to discuss where the organisations Landcare and Integrated Catchment Management in Australia fit with these. The paper will also present results of investigations of the contribution these organisations have made to the management of common resources, focusing particularly on the State of Queensland. Landcare and Integrated Catchment Management are community participative organisations with a diverse membership that includes primary producers, nature conservationists, government and industry. They involve all members of the community in the decision-making process for the management of catchments. Both these organisations mould together private use of land for agriculture with a philosophy that all land is held in trust for the use of future generations of human and other life. They do this by planning for long-term, sustainable use of land at a catchment level and use public and private funds to implement the plans at a property level. Members of the organisations work together, and work with government bodies, to share information about best practice and to make incremental steps towards sustainable land use. Nature conservation groups are part of both organisations and contribute to the thinking about what is current best practice for the needs of wildlife. They also help to implement the plans using both public funds and private donations of cash or kind. However, the planning and implementation of the plans drawn up by Landcare and Integrated Catchment Management can be problematic for a number of reasons, including the lack of involvement of local industry and government.
Effect of 5'-UTR mutations on HCV replication
Creators: name: Mercuri, Luca
Publisher: name: Imperial College London
Year: 2013

description: Hepatitis C Virus (HCV) is an emerging and challenging virus due to the problematic understanding of its persistence mechanisms. In fact, for many years scientists have been trying to resolve the issue of HCV lymphotropism, as the virus has been detected in peripheral blood mononuclear cells (PBMCs), lymph nodes and brain tissue. HCV isolates detected in these extrahepatic sites have unique mutations at positions 107, 204 and 243, distinct from liver and serum, in the internal ribosomal entry site (IRES) located in the 5’ UTR, one of the most well conserved regions of the HCV genome. In this study, divergent IRES variants were detected in the PBMCs of HCV-infected patients. Differences were found among plasma and PBMC derived 5’ UTRs. Most of the PBMC-derived sequences contained the AAA mutations in the IRES affecting the aforementioned positions, a unique quasispecies population in PBMCs compared with plasma. The effect of mutations detected in the IRES was predicted based on its secondary structure. The three mutations alone and in combination detected in lymphotropic quasispecies were introduced in the 5’ UTR of HCV isolate JFH-1 and replicon genotype 1b to study the effect of these mutations on HCV replication in different cell lines. The replication capacity of HCV mutants was tested in the Huh7.5, Jurkat, EBV+ B and PBMC cell lines to examine whether such mutations had an effect on the efficiency of the virus to replicate in extrahepatic cell lines. All mutant constructs infected and showed robust replication in Huh7.5 cells. Jurkat cells failed to become infected while EBV+ B lymphocyte cells were shown to support HCV mutant replication. PBMCs failed to become infected with HCV mutants and transfection of such cells with siRNAs against IRF3 and NF-kB did not improve this outcome as they appeared to not have an impact on the innate immune response through failure to inhibit IRF3 and NF-kB gene expression. On the other hand, all cell lines were found to be susceptible to infection with HCV containing plasma. HCV mutants were able to target cells of the immune system but replicated with reduced efficiency compared to hepatocytes. Mutations that were detected in HCV mutants following replication in extrahepatic cells caused changes in the thermodynamic stability of the IRES that resulted in predicted structural changes.
A numerical investigation of internal gravity wave phenomena with adaptive mesh techniques
Creators: name: Martin, Benjamin
Publisher: name: Imperial College London
Year: 2014

description: Internal gravity waves in the oceans are a limited scale process capable of providing sufficient energy to activate strong diapycnal mixing near sloping bathymetry. This can account for a significant portion of oceanic vertical mixing. Mixing can be locally intense, transporting colder nutrient-rich bottom water up onto continental margins with implications for coastal marine ecosystems and the carbon cycle. Modelling internal waves is particularly challenging. The strong vertical accelerations present in the overturning and breaking of internal waves necessitates a non-hydrostatic model, and the small-scale processes that result from the interaction of internal waves with bathymetry mean that traditional structured mesh models require high-resolution to adequately capture flow complexity. I present two-dimensional results of numerical simulations of internal waves being generated and interacting with idealised bathymetry, using the Imperial College Ocean Model (Fluidity-ICOM), a non-hydrostatic, finite-element, unstructured mesh model incorporating anisotropic mesh adaptivity. The unstructured nature of Fluidity-ICOM allows the mesh to be optimised to represent complex bathymetries, as well as capturing the vertically inhomogeneous structure of internal waves. Convergence of the model to analytical results has been demonstrated by modelling internal wave propagation in a linearly stratified fluid. Adaptive mesh simulations have been found to adequately capture the dynamics of internal wave breaking at a slope, and the degeneration of interfacial waves into solitary internal waves, with less computational resources than traditional models. However, further work is needed to simulate the internal leewave generation mechanism of flow over topography.
Gamma-Ray Burst 980329 and its X-Ray Afterglow
Creators: name: Zand, J. J. M. in 't
name: Amati, L.
name: Antonelli, L. A.
name: Butler, R. C.
name: Castro-Tirado, A. J.
name: Coletta, A.
name: Costa, E.
name: Feroci, M.
name: Frontera, F.
name: Heise, J.
name: Molendi, S.
name: Nicastro, L.
name: Owens, A.
name: Palazzi, E.
name: Pian, E.
name: Piro, L.
name: Pizzichini, G.
name: Smith, M. J. S.
name: Tavani, M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: GRB 980329 is the brightest gamma-ray burst detected so far with the Wide Field Cameras aboard BeppoSAX, both in gamma-rays and X-rays. With respect to its fluence (2.6 X 10**-5 erg/s/cm**2 in 50 to 300 keV) it would be in the top 4% of gamma-ray bursts in the 4B catalog (Meegan et al. 1998). The time-averaged burst spectrum from 2 to 20 and 70 to 650 keV can be well described by the empirical model of Band et al. (1993). The resulting photon index above the break energy is exceptionally hard at -1.32 +/- 0.03. An X-ray afterglow was detected with the narrow-field instruments aboard BeppoSAX 7 h after the event within the error box as determined with the Wide Field Cameras. Its peak flux is (1.4 +/- 0.2) X 10**-12 erg/s/cm**2 (2 to 10 keV). The afterglow decayed according to a power law function with an index of -1.35 +/- 0.03. GRB 980329 is characterized by being bright and hard, and lacking strong spectral evolution.
description: 13 pages with 3 figures. Accepted for publication in ApJ Lett
Internal dynamics of the Large Magellanic Cloud from Gaia DR2
Creators: name: Vasiliev, Eugene
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We use the proper motions (PM) of half a million red giant stars in Large Magellanic Cloud measured by Gaia to construct a 2d kinematic map of mean PM and its dispersion across the galaxy, out to 7 Kpc from its centre. We then explore a range of dynamical models and measure the rotation curve, mean azimuthal velocity, velocity dispersion profiles, and the orientation of the galaxy. We find that the circular velocity reaches 90 km/s at 5 Kpc, and that the velocity dispersion ranges from 30-40 km/s in the galaxy centre to 15-20 km/s at 7 Kpc.
description: revised kinematic maps; matches the published version
Myrmecophaga didactyla Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Pilosa
Myrmecophagidae
Myrmecophaga
Myrmecophaga didactyla

description: Myrmecophaga didactyla [spec. nov.]
M. palmis didactylis, plantis tetradactylis. Syst. nat. 8. Mus. Ad. Fr. 8. *
Tamandua S. Coati americana alba. Seb. mus. 1. p. 60. t. 37. f. 3.
Habitat in America australi.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 35, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206