cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Reservoirs learn to learn
Creators: name: Subramoney, Anand
name: Scherr, Franz
name: Maass, Wolfgang
Publisher: name: arXiv
Year: 2019
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: FOS: Computer and information sciences

description: We consider reservoirs in the form of liquid state machines, i.e., recurrently connected networks of spiking neurons with randomly chosen weights. So far only the weights of a linear readout were adapted for a specific task. We wondered whether the performance of liquid state machines can be improved if the recurrent weights are chosen with a purpose, rather than randomly. After all, weights of recurrent connections in the brain are also not assumed to be randomly chosen. Rather, these weights were probably optimized during evolution, development, and prior learning experiences for specific task domains. In order to examine the benefits of choosing recurrent weights within a liquid with a purpose, we applied the Learning-to-Learn (L2L) paradigm to our model: We optimized the weights of the recurrent connections -- and hence the dynamics of the liquid state machine -- for a large family of potential learning tasks, which the network might have to learn later through modification of the weights of readout neurons. We found that this two-tiered process substantially improves the learning speed of liquid state machines for specific tasks. In fact, this learning speed increases further if one does not train the weights of linear readouts at all, and relies instead on the internal dynamics and fading memory of the network for remembering salient information that it could extract from preceding examples for the current learning task. This second type of learning has recently been proposed to underlie fast learning in the prefrontal cortex and motor cortex, and hence it is of interest to explore its performance also in models. Since liquid state machines share many properties with other types of reservoirs, our results raise the question whether L2L conveys similar benefits also to these other reservoirs.
Additional file 2 of Catheter ablation versus medical therapy in atrial fibrillation: an umbrella review of meta-analyses of randomized clinical trials
Creators: name: Titus, Anoop
name: Syeed, Sakil
name: Baburaj, Abiram
name: Bhanushali, Karan
name: Gaikwad, Pramod
name: Sooraj, Mannil
name: Saji, Anu Mariam
name: Mir, Wasey Ali Yadullahi
name: Kumar, Pramukh Arun
name: Dasari, Mahati
name: Ahmed, Mubashir Ayaz
name: Khan, Mohammed Omer
name: Titus, Aishwarya
name: Gaur, Janamjey
name: Annappah, Dilanthy
name: Raj, Arjun
name: Noreen, Nabeela
name: Hasdianda, Adrian
name: Sattar, Yasar
name: Narasimhan, Bharat
name: Mehta, Nishaki
name: Desimone, Christopher V.
name: Deshmukh, Abhishek
name: Ganatra, Sarju
name: Nasir, Khurram
name: Dani, Sourbha
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2: AMSTAR 2: Critical appraisal tool for systematic reviews that includes randomized or non-randomized studies of healthcare interventions, or both
Characterization and differentiation of the tumor microenvironment (TME) of orthotopic and subcutaneously grown head and neck squamous cell carcinoma (HNSCC) in immunocompetent mice
Creators: name: Brand, Matthias
name: Laban, Simon
name: Theodoraki, Marie-Nicole
name: Doescher, Johannes
name: Hoffmann, Thomas K.
name: Schuler, Patrick J.
name: Brunner, Cornelia
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: tumor microenvironment
subject: head and neck cancer
subject: SCC VII orthotopic mouse model
subject: SCC VII subcutaneous mouse model
subject: regulatory B cells
subject: adenosine-related immunosuppression
subject: tumor-infiltrating lymphocytes
subject: CD4+ T cells
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Squamous cell carcinoma of head and neck
subject: Immunosuppression therapy
subject: T-Lymphocytes
subject: Lymphocytes, Tumor-infiltrating
subject: Plattenepithelcarcinom
subject: Hals-Nasen-Ohren-Tumor
subject: T-Lymphozyt
subject: B-Lymphozyt
subject: Immunsuppression

description: For the development and evaluation of new head and neck squamous cell carcinoma (HNSCC) therapeutics, suitable, well-characterized animal models are needed. Thus, by analyzing orthotopic versus subcutaneous models of HNSCC in immunocompetent mice, we evaluated the existence of adenosine-related immunosuppressive B- and T lymphocyte populations within the tumor microenvironment (TME). Applying the SCC VII model for the induction of HNSCC in immunocompetent C3H/HeN mice, the cellular TME was characterized after tumor initiation over time by flow cytometry. The TME in orthotopic grown tumors revealed a larger population of tumor-infiltrating lymphocytes (TIL) with more B cells and CD4+ T cells than the subcutaneously grown tumors. Immune cell populations in the blood and bone marrow showed a rather distinct reaction toward tumor induction and tumor location compared to the spleen, lymph nodes, or thymus. In addition, large numbers of immunosuppressive B- and T cells were identified within the TME but also in secondary lymphoid organs, independently of the tumor initiation site. The altered immunogenic TME may influence the response to any treatment attempt. Moreover, when analyzing the TME and other lymphoid organs of tumor-bearing mice, we observed conditions reflecting largely those of patients suffering from HNSCC suggesting the C3H/HeN mouse model as a suitable tool for studies aiming to target immunosuppression to improve anti-cancer therapies.
sj-docx-1-cjx-10.1177_15501906221130535 – Supplemental material for Shining Light on Labels in the Dark: Guidelines for Offensive Collections Materials
Creators: name: Briscoe, Laura
name: Nazaire, Mare
name: Allen, J. Ryan
name: Baker, Janelle
name: Donnell Davenport, Aliya
name: Mansaray, Janet
name: McCormick, Carol Ann
name: Santiago Coyle, McKenna
name: Schmull, Michaela
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 89999 Information and Computing Sciences not elsewhere classified
subject: FOS: Computer and information sciences

description: Supplemental material, sj-docx-1-cjx-10.1177_15501906221130535 for Shining Light on Labels in the Dark: Guidelines for Offensive Collections Materials by Laura Briscoe, Mare Nazaire, J. Ryan Allen, Janelle Baker, Aliya Donnell Davenport, Janet Mansaray, Carol Ann McCormick, McKenna Santiago Coyle and Michaela Schmull in Collections: A Journal for Museum and Archives Professionals
Topologically semisimple and topologically perfect topological rings
Creators: name: Positselski, Leonid
name: Stovicek, Jan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Category Theory (math.CT)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics

description: Extending the Wedderburn-Artin theory of (classically) semisimple associative rings to the realm of topological rings with right linear topology, we show that the abelian category of left contramodules over such a ring is split (equivalently, semisimple) if and only if the abelian category of discrete right modules over the same ring is split (equivalently, semisimple). Our results in this direction complement those of Iovanov-Mesyan-Reyes. An extension of the Bass theory of left perfect rings to the topological realm is formulated as a list of conjecturally equivalent conditions, many equivalences and implications between which we prove. In particular, all the conditions are equivalent for topological rings with a countable base of neighborhoods of zero and for topologically right coherent topological rings. Considering the rings of endomorphisms of modules as topological rings with the finite topology, we establish a close connection between the concept of a topologically perfect topological ring and the theory of modules with perfect decomposition. Our results also apply to endomorphism rings and direct sum decompositions of objects in certain additive categories more general than the categories of modules; we call them topologically agreeable categories. We show that any topologically agreeable split abelian category is Grothendieck and semisimple. We also prove that a module $Σ$-coperfect over its endomorphism ring has a perfect decomposition provided that either the endomorphism ring is commutative or the module is countably generated, partially answering a question of Angeleri Hugel and Saorin.
description: LaTeX 2e with tikz-cd, 69 pages; v.3: new Section 13 inserted, final Section 14 (former 13) rewritten with much more complete picture obtained using new results of arXiv:1911.11720, Lemma 7.2 deleted as no longer relevant, Examples 3.7(2) and 9.4 inserted; v.4: Remarks 3.11 and 7.2 inserted; v.5: misprints corrected, references updated, a reference to Example 10.2 in arXiv:2110.13105 added
Data from: Postcrania of Borealestes (Mammaliformes: Docodonta) and the emergence of ecomorphological diversity in early mammals
Creators: name: Panciroli, Elsa
name: Benson, Roger
name: Fernandez, Vincent
name: Humpage, Matthew
name: Martin-Serra, Alberto
name: Walsh, Stig
name: Luo, Zhe-Xi
name: Fraser, Nick
Publisher: name: Zenodo
Year: 2021
Subjects: Mammals
Scotland
Middle Jurassic
ecomorphology
Bathonian

description: The Middle Jurassic witnessed the early diversification of mammal groups, including the stem-mammalian clade, Docodonta. Recent discoveries in China indicate docodontans exhibited ecomorphological diversity akin to small-bodied mammals living >100 million years later, in the Cenozoic. Our understanding of the emergence of this ecological diversity is hindered by a lack of Middle Jurassic fossil material from other parts of the world. The two partial postcranial skeletons of Borealestes described here come from the Kilmaluag Formation, Scotland. These are the most complete Mesozoic mammaliaform skeletons currently known from the UK, and among the best preserved in Europe. As an early member of Docodonta, Borealestes provides key anatomical information for understanding the clade's evolution, and the emergence of mammaliaform ecomorphological diversity. Using digital reconstructions from micro-CT and synchrotron scans, we describe the postcranial anatomy of Borealestes and provide an updated phylogenetic analysis incorporating cranial and postcranial characters. We find Borealestes species form a sister group to a clade comprising Agilodocodon and Microdocodon. To complement observational analyses of the skeleton, we carry out principle components analyses using 3D landmarks on a comparative dataset of 42 extant mammal taxa. Our results indicate Borealestes lacked specialisations for derived locomotor behaviour. We detect some similarity in the humerus between Borealestes and Ornithorhynchus. Borealestes is morphologically intermediate between the robust morphology of fossorial and semi-fossorial/semi-aquatic Haldanodon and Docofossor, and the gracile morphology for scansorial Agilodocodon and Microdocodon. We suggest ecological diversity in Docodonta may arise from an unspecialised basal bauplan, of which Borealestes may be representative.
title: Bildung biogener Amine in fermentierten Würsten in Abhängigkeit vom Frischezustand und der Ausgangskeimzahl des Rohmaterials unter besonderer Berücksichtigung der Enterokokken
Creators: name: Neuhold, Birgit
Year: 2009

description: Ziel der vorliegenden Arbeit war es, den Zusammenhang zwischen der Bildung biogener Amine in Rohwürsten und dem Frischezustand des Rohmaterials aufzuzeigen. Der Rolle der Enterokokken wurde dabei spezielle Beachtung geschenkt. Das verwendete Rohmaterial (Faschiertes) wurde vor der Rohwurstherstellung zwischen 0 und 10 Tagen bei 4°C gelagert, anschließend wurden sie über 7 Tage bei 18°C gereift. Zusätzlich wurden in zwei Versuchen Enterokokken mit einer Konzentration von 103 kbE/g Rohmaterial und in einem Versuch mit einer Konzentration von 106 kbE/g zugesetzt. Es konnte ein Anstieg der Enterobakteriaceen und Pseudomonaden im Rohmaterial über die Lagerdauer hinweg nachgewiesen werden. Der Gehalt an den Diaminen Putrescin und Cadaverin war in Würsten, deren Rohmaterial 7 oder 10 gelagert worden war, deutlich höher als in Würsten aus frischem Fleisch. Auch der Gehalt an Tyramin spiegelte die Lagerungsdauer des Rohmaterials vor der Wurstherstellung wieder. Da sich der Gehalt an Enterokokken über die Lagerungs- und Reifungsdauer kaum änderte, können Enterokokken als Indikatoren für die mikrobielle Kontamination des Rohmaterials dienen. Die Konzentrationen an Putrescin, Cadaverin sowie Tyramin können Rückschlüsse auf Fehler während der Lagerung und Reifung von Rohwürsten erlauben.
Quantum optimal control using phase-modulated driving fields
Creators: name: Tian, Jiazhao
name: Liu, Haibin
name: Liu, Yu
name: Yang, Pengcheng
name: Betzholz, Ralf
name: Said, Ressa S.
name: Jelezko, Fedor
name: Cai, Jianming
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Quantum control
subject: DDC 530 / Physics
subject: Hamiltonian systems
subject: Hamiltonian operator
subject: Hamilton-Operator

description: Quantum optimal control represents a powerful technique to enhance the performance of quantum experiments by engineering the controllable parameters of the Hamiltonian. However, the computational overhead for the necessary optimization of these control parameters drastically increases as their number grows. We devise a variant of a gradient-free optimal-control method by introducing the idea of phase-modulated driving fields, which allows us to find optimal control fields efficiently. We numerically evaluate its performance and demonstrate the advantages over standard Fourier-basis methods in controlling an ensemble of two-level systems showing an inhomogeneous broadening. The control fields optimized with the phase-modulated method provide an increased robustness against such ensemble inhomogeneities as well as control-field fluctuations and environmental noise, with one order of magnitude less of average search time. Robustness enhancement of single quantum gates is also achieved by the phase-modulated method. Under environmental noise, an XY-8 sequence constituted by optimized gates prolongs the coherence time by 50% compared with standard rectangular pulses in our numerical simulations, showing the application potential of our phase-modulated method in improving the precision of signal detection in the field of quantum sensing.
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 312 (41. Jg.), November 2011
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: DDC 050 / General serial publications
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
Additional file 2 of New insights into bioaugmented removal of sulfamethoxazole in sediment microcosms: degradation efficiency, ecological risk and microbial mechanisms
Creators: name: Chen, Jianfei
name: Chen, Xiuli
name: Zhu, Ying
name: Yan, Shuang
name: Xie, Shuguang
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Supplementary Methods. Real-time q-PCR assay. Computational analysis of 16S rRNA gene high-throughput sequencing. Metagenomics analysis. SIP gradient fractionation. Data pre-processing. Network analysis. Fig. S1. Relative abundance of the dominant phyla (all taxonomic groups except for the top 7 were merged into the “Others” group) (A). Comparison of the phylum distribution between SMX-amended treatments (treatments C, D and E) and non-SMX-amended control (treatment B) (B) and between inoculation treatments (treatments D and E) and non-inoculation treatment (treatment C) (C). Fig. S2. Comparison of the different genus distribution between inoculation treatments (treatments D and E) and non-inoculation treatment (treatment C). Fig. S3. Relative abundance of ASVs along buoyant density gradients from the treatment inoculated with Pseudomonas sp. M2. Fig. S4. Relative abundance of ASVs along buoyant density gradients from the treatment inoculated with Paenarthrobacter sp. R1. Fig. S5. Phylogenetic tree using single-copy gene of all assembled bins.
Holism as the significance of gauge symmetries
Creators: name: Gomes, Henrique
Publisher: name: arXiv
Year: 2019
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: Not all symmetries are on a par. For instance, within Newtonian mechanics, we seem to have a good grasp on the empirical significance of boosts, by applying it to subsystems. This is exemplified by the thought experiment known as Galileo's ship: the inertial state of motion of a ship is immaterial to how events unfold in the cabin, but is registered in the values of relational quantities such as the distance and velocity of the ship relative to the shore. But the significance of gauge symmetries seems less clear. For example, can gauge transformations in Yang-Mills theory---taken as mere descriptive redundancy---exhibit a similar relational empirical significance as the boosts of Galileo's ship? This question has been debated in the last fifteen years in philosophy of physics. I will argue that the answer is `yes', but only for a finite subset of gauge transformations, and under special conditions. Under those conditions, we can mathematically identify empirical significance with a failure of supervenience: the state of the Universe is not uniquely determined by the intrinsic state of its isolated subsystems. Empirical significance is therefore encoded in those relations between subsystems that stand apart from their intrinsic states.
description: 29 pages, 4 page appendix, 1 figure. V2: Argument streamlined and new counter-examples to previous definitions of DES through quotients
Supplemental Material - Listening to music videos on YouTube. Digital consumption practices and the environmental impact of streaming
Creators: name: Beuscart, Jean-Samuel
name: Coavoux, Samuel
name: Garrocq, Jean-Baptiste
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 200299 Cultural Studies not elsewhere classified
subject: FOS: Other humanities
subject: Sociology
subject: FOS: Sociology

description: Supplemental Material for Listening to music videos on YouTube. Digital consumption practices and the environmental impact of streaming by Jean-Samuel Beuscart, Samuel Coavoux, and Jean-Baptiste Garrocq in Journal of Consumer Culture
Supplemental Material - Impact of the COVID-19 Pandemic on Diagnostic Frequency of Febrile Seizures: An Electronic Health Record Database Observational Study
Creators: name: Cadet, Katsiah
name: Ceneviva, Gary D
name: Walter, Vonn
name: Thomas, Neal J
name: Krawiec, Conrad
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases

description: Supplemental Material for Impact of the COVID-19 Pandemic on Diagnostic Frequency of Febrile Seizures: An Electronic Health Record Database Observational Study by Katsiah Cadet, Gary D Ceneviva, Vonn Walter, Neal J Thomas, and Conrad Krawiec in The Neurohospitalist
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 334 (45. Jg.), November 2015
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: DDC 050 / General serial publications
subject: Universities; Germany; Ulm
subject: Universität Ulm

description: uni ulm intern, Das Ulmer Universitätsmagazin, Heft Nr. 334 (45. Jg.), November 2015
Conceptual and Methodological Framework on the Availability and Recoverability of Secondary Raw Materials focusing on Critical Raw Materials
Creators: name: Remmen, Kirsten
name: Capelli, Manuele
name: Roesslein, Matthias
name: Beylot, Antoine
name: Monfort Climent, Daniel
name: Korf, Nathalie
name: Rotter, Vera Susanne
name: Wäger, Patrick
Publisher: name: Zenodo
Year: 2024
Subjects: Recoverability of Secondary Raw Materials
Availability of Secondary Raw Materials
Critical Raw Materials (CRMs)

description: he effective management of raw material supply and demand requires reliable and complete information and foresight on Secondary Raw Materials (SRMs) stocks and flows throughout their life cycles. Therefore, having knowledge about the availability and recoverability of SRMs, especially Critical Raw Materials (CRMs), is crucial. Existing knowledge platforms, such as the Urban Mine Platform (www.urbanmineplatform.eu) do not include the recoverability of SRMs or CRMs. During the Horizon Europe project FutuRaM, a conceptual framework is developed, extending existing frameworks to include recycling pathways showing both the availability and recoverability of SRMs. The FutuRaM framework includes four post-consumer waste streams (vehicles, batteries, electronic and electrical equipment, construction and demolition) as well as tailings from mining activities and slags and ashes. 

 

In the first step, the concepts of "availability" and "recoverability" need to be defined by integrating all necessary requirements and boundary conditions of the six FutuRaM waste streams. This includes addressing aspects such as the quality of recycling or the fast development of innovative recycling technologies to ensure a comprehensive definition and subsequent assessment of recoverability. A conducted literature study further highlighted the need to build the FutuRaM framework on existing concepts and frameworks, e.g., the System of Environmental-Economic Accounting (SEEA) framework. To increase functionality of the developed framework, it is crucial to integrate available data, such as the European Waste Statistics data sets. In a further step, this available but widely scattered data needs to be harmonized to be fit for use in a SRMs availability and recoverability assessment. The harmonization and consolidation of data sets include the integration of an uncertainty assessment, which builds the basis for providing reliable information. 

 

In our contribution, we will present the FutuRaM conceptual and methodological framework that aims to effectively support informed decision-making on the recoverability of SRMs and CRMs. This framework will be exemplified through case studies showing the crucial steps during the development in order to successfully contribute to advancing resource management for industry, policymakers, and researchers.
Supplemental Material - Young People’s Sexual Wellbeing: A Qualitative Evidence Synthesis Protocol
Creators: name: Bosó Pérez, Raquel
name: Lewis, Ruth
name: Littlejohn, Jennifer
name: Willis, Malachi
name: Mitchell, Kirstin R.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111099 Nursing not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental Material for Young People’s Sexual Wellbeing: A Qualitative Evidence Synthesis Protocol by Raquel Boso Perez, Ruth Lewis, Jennifer Littlejohn, Malachi Willis, and Kirstin R. Mitchell in International Journal of Qualitative Methods
Additional file 1 of Automated segmentation of lesions and organs at risk on [68Ga]Ga-PSMA-11 PET/CT images using self-supervised learning with Swin UNETR
Creators: name: Yazdani, Elmira
name: Karamzadeh-Ziarati, Najme
name: Cheshmi, Seyyed Saeid
name: Sadeghi, Mahdi
name: Geramifar, Parham
name: Vosoughi, Habibeh
name: Jahromi, Mahmood Kazemi
name: Kheradpisheh, Saeed Reza
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Cell Biology
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Supplementary Material 1: S1. Patient characteristics. S2. Pre-training loss function calculation. S3. Evaluation metrics
sj-docx-2-jpc-10.1177_21501319221129731 – Supplemental material for Obesity and Patient Activation: Confidence, Communication, and Information Seeking Behavior
Creators: name: Chang, Ji Eun
name: Lindenfeld, Zoe
name: Chang, Virginia W.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified

description: Supplemental material, sj-docx-2-jpc-10.1177_21501319221129731 for Obesity and Patient Activation: Confidence, Communication, and Information Seeking Behavior by Ji Eun Chang, Zoe Lindenfeld and Virginia W. Chang in Journal of Primary Care & Community Health
Comparison of Measurement and Readout Strategies for RO-PUFs on Xilinx Zynq-7000 SoC FPGAs
Creators: name: Herkle, Andreas
name: Rossak, Philipp
name: Mandry, Holger
name: Becker, Joachim
name: Ortmanns, Maurits
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Physical Unclonable Functions
subject: DDC 620 / Engineering & allied operations
subject: Time measurements
subject: Field programmable gate arrays
subject: Semiconductors
subject: Computer input-output equipment
subject: Data transmission systems
subject: Zeitmessung
subject: Field programmable gate array
subject: Halbleiter
subject: Hardware

description: Physical unclonable functions are integrated circuits well-known for their potential to replace dedicated secure storage of cryptographic keys. On FGPAs, ring-oscillators have received great attention as the most preferable implementation. Many measurement data sets have been published with large quantities of ring-oscillators on large quantities of chips. Yet, all these data sets are missing large quantities of readouts, which limits their usage for proving the efficiency of error correction algorithms. In this work, we present multiple different approaches of measurement control and readout extraction for external storage. We cover the full development process, beginning with slow extraction in early stages for maximum control up to final extraction with automated high-speed designs. Targeting a Zynq-7000 architecture, the final design extracts 3800 · 10000 readouts within 8.04 s, which relates to a data extraction rate of 36 Mbit/s. In comparison to an early stage design, which took 452.91 s for the same measurement, a reduction in total run time of 98.2% was achieved.
Iterative Non-iterative Integrals in Quantum Field Theory
Creators: name: Blümlein, Johannes
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2018

description: Single scale Feynman integrals in quantum field theories obey difference or differential equations with respect to their discrete parameter $N$ or continuous parameter $x$. The analysis of these equations reveals to which order they factorize, which can be different in both cases. The simplest systems are the ones which factorize to first order. For them complete solution algorithms exist. The next interesting level is formed by those cases in which also irreducible second order systems emerge. We give a survey on the latter case. The solutions can be obtained as general $_2F_1$ solutions. The corresponding solutions of the associated inhomogeneous differential equations form so-called iterative non-iterative integrals. There are known conditions under which one may represent the solutions by complete elliptic integrals. In this case one may find representations in terms of meromorphic modular functions, out of which special cases allow representations in the framework of elliptic polylogarithms with generalized parameters. These are in general weighted by a power of $1/\eta(\tau)$, where $\eta(\tau)$ is Dedekind's $\eta$-function. Single scale elliptic solutions emerge in the $\rho$-parameter, which we use as an illustrative example. They also occur in the 3-loop QCD corrections to massive operator matrix elements and the massive 3-loop form factors.
title: Untersuchung der Wirkung von WHG 56T an verschiedenen isolierten Präparaten von Meerschweinchen
Creators: name: El Tahan, Mona
Year: 2009

description: In dieser Arbeit wurde die Testsubstanz WHG56T auf ihre negativ inotrope, chronotrope Wirkung an verschiedenen Präparaten des Meerschweinchens untersucht. Alle Versuchsreihen wurden nach der von Reiter(1967) beschriebenen Methode zur isometrischen Kontraktionsmessung an isolierten Präparaten von Meerschweinchen durchgeführt. Die isolierten Präparate wurden in Organbad eingebracht, dass mit physiologischer, kontinuierlich mit Oxymix (95% O2, 5% CO2) durchgeperlter Elekrolytlösung gefüllt war. Die Substanz wurde bis zu einer Konzentration von 100μmol/l getestet. An spontan schlagenden rechten Vorhöfen hat die Testsubstanz keine Wirkung auf Schlagfrequenz und die zeigt keine signifikante chronotrope Wirkung. An elektrische stimulierten Papillarmuskeln zeigte die Substanz eine schwach negativ inotrope Wirkung bis zu Konzentration 30μmol/l . Die Testsubstanz hatte keine Wirkung auf kontrahierte Gefäße wie Aorta und Arteria pulmonalis. An terminalen Ilea zeigte die Testsubstanz eine starke spamsolytische Wirkung und somit einen gewebespezifischen Effekt.
The cardenolide glycoside acovenoside a interferes with epidermal growth factor receptor trafficking in non-small cell lung cancer cells
Creators: name: Hafner, Susanne
name: Schmiech, Michael
name: Lang, Sophia Johanna
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: cardenolide glycoside
subject: Na+/K+-ATPase
subject: non-small cell lung cancer
subject: EGFR
subject: endosomal arrest
subject: DDC 610 / Medicine & health
subject: Carcinoma, Non-small-cell lung
subject: Glycosides
subject: Apoptosis
subject: ErbB receptors
subject: Ubiquitination
subject: Nicht-kleinzelliges Bronchialkarzinom
subject: Glykoside
subject: Ubiquitinierung

description: Cardenolide glycosides are natural compounds known to inhibit the ion pumping function of the Na+/K+-ATPase in cellular systems. Interestingly, various cancer cell types are highly susceptible to cardenolide glycosides. Herein, we explore the cardenolide glycoside Acovenoside A (AcoA) with respect to its influences on human A549 non-small cell lung cancer (NSCLC) cells. We found that exposure to AcoA, digoxin and ouabain increases intracellular sodium and ATP levels indicating that the ion pumping function of the transmembrane Na+/K+-ATPase is effectively inhibited. Like digoxin and ouabain, AcoA inhibits transcription factor NF-κB activation and induces apoptotic cell death in NSCLC cells. This was confirmed by a preclinical in vivo model in which AcoA treatment of NSCLC xenografts grown on chick chorioallantoic membranes inhibited the expression of proliferation antigen Ki-67 and induced apoptotic DNA strand breaks. We aimed to elucidate the underlying mechanisms. The Na+/K+-ATPase transmembrane complex contains Src kinase and epidermal growth factor receptor (EGFR). Indeed, we found that AcoA activates Src kinase in A549 cells, but not in a cell-free assay using recombinant Src kinase. Src kinase is a downstream target of EGFR, and correlation analysis using the NCI60 database pointed to a role of EGFR in cardenolide glycoside-induced cancer cell death. Accordingly, NSCLC cells expressing hyperphosphorylated EGFRmut exhibited resistance to AcoA. To investigate the interaction between cardenolide glycosides and EGFR in detail, we performed immunoblotting studies: Whereas ligand binding and EGFR phosphorylation were not significantly affected, ubiquitinated EGFR accumulated after prolonged incubation with AcoA. To visualize EGFR trafficking we used A549 cells transfected with a fluorescent biosensor which binds to activated EGFR. Pretreatment with AcoA and digoxin induced accumulation of EGFR in endosomal compartments thus inhibiting EGF-induced EGFR degradation comparable to the Na+ ionophore monensin, a known inducer of EGFR endosomal arrest. Intracellular Na+ concentrations regulate EGFR trafficking and signaling. Na+ homeostasis is maintained by the Na+/K+-ATPase, which might account for its close interaction with the EGFR. Cardenolide glycosides inhibit the ATP-dependent Na+/K+ exchange through the Na+/K+-ATPase resulting in higher intracellular Na+ levels. Our data provide first evidence that this impedes efficient EGFR trafficking at the endosomal compartment.
Additional file 2 of Automated segmentation of lesions and organs at risk on [68Ga]Ga-PSMA-11 PET/CT images using self-supervised learning with Swin UNETR
Creators: name: Yazdani, Elmira
name: Karamzadeh-Ziarati, Najme
name: Cheshmi, Seyyed Saeid
name: Sadeghi, Mahdi
name: Geramifar, Parham
name: Vosoughi, Habibeh
name: Jahromi, Mahmood Kazemi
name: Kheradpisheh, Saeed Reza
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Cell Biology
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Supplementary Material 2: Network architecture guideline of Fig. 2
sj-pdf-5-hpi-10.1177_11207000221130270 – Supplemental material for Operative management of metastatic disease of the acetabulum: review of the literature and prevailing concepts
Creators: name: Christ, Alexander B
name: Bartelstein, Meredith K
name: Kenan, Shachar
name: Ogura, Koichi
name: Fujiwara, Tomohiro
name: Healey, John H
name: Fabbri, Nicola
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-5-hpi-10.1177_11207000221130270 for Operative management of metastatic disease of the acetabulum: review of the literature and prevailing concepts by Alexander B Christ, Meredith K Bartelstein, Shachar Kenan, Koichi Ogura, Tomohiro Fujiwara, John H Healey and Nicola Fabbri in HIP International
sj-docx-1-qjp-10.1177_17470218221128780 – Supplemental material for Rate of forgetting is independent from initial degree of learning across different age groups
Creators: name: Rivera-Lares, Karim
name: Sala, Sergio Della
name: Baddeley, Alan
name: Logie, Robert
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-qjp-10.1177_17470218221128780 for Rate of forgetting is independent from initial degree of learning across different age groups by Karim Rivera-Lares, Sergio Della Sala, Alan Baddeley and Robert Logie in Quarterly Journal of Experimental Psychology
O desenvolvimento de competências gerenciais no Instituto Federal de      Rondônia - campus Colorado do Oeste: uma proposta de capacitação gerencial.
Creators: name: Mayuma Martins Santana Viana
name: Débora Vargas Ferreira Costa
Publisher: name: Zenodo
Year: 2024

description: A capacitação gerencial aqui apresentada, tem como objetivo preparar os gestores de nível intermediário do IFRO a enfrentar os desafios de um ambiente de trabalho dinâmico, liderar equipes de maneira eficiente e alcançar os objetivos setoriais, indo de encontro com os objetivos estratégicos da instituição como um todo.
title: O desenvolvimento de competências gerenciais no Instituto Federal de Rondônia - campus Colorado do Oeste: uma proposta de capacitação gerencial
title: Não
titleType: AlternativeTitle
Creators: name: Mayuma Martins Santana Viana
name: Débora Vargas Ferreira Costa
Publisher: name: Zenodo
Year: 2024

description: O presente produto tecnológico é resultado da dissertação de mestrado profissional em Gestão e Estratégia da Universidade Federal Rural do Rio de Janeiro (UFRRJ), defendida por Mayuma Martins Santana Viana sob orientação da Profa. Dra. Débora Vargas Ferreira Costa. A produção consiste na elaboração de um Curso de Capacitação Gerencial voltado a servidores do Instituto Federal de Educação, Ciência e Tecnologia de Rondônia (IFRO) – campus Colorado do Oeste, com foco no desenvolvimento de competências gerenciais essenciais à atuação de gestores de nível intermediário. Alinhado à linha de pesquisa “Estratégia de Gestão de Pessoas e Organizações” do Programa de Pós-Graduação em Gestão e Estratégia (PPGE/UFRRJ), especialmente ao projeto “Estratégias de Gestão de Pessoas, Liderança Organizacional e Relações de Trabalho”, o curso visa preparar os gestores para liderar equipes de forma eficiente, enfrentar desafios cotidianos e contribuir para o alcance dos objetivos estratégicos institucionais. Com médio grau de inovação, a proposta combina conhecimentos pré-estabelecidos, organizados em quatro eixos temáticos: competências institucionais, comportamentais, funcionais e políticas. A capacitação, com carga horária mínima de 220 horas, integra cursos de curta duração e encontros de compartilhamento de experiências, podendo ser ofertada presencialmente ou a distância. Os recursos didáticos e metodológicos incluem apostilas digitais, oficinas práticas, rodas de conversa e plataformas como a ENAP. O impacto esperado inclui a melhoria do desempenho dos gestores, a elevação da qualidade na prestação de serviços públicos e a promoção de mudanças organizacionais significativas, por meio da aprendizagem experiencial e da aplicação prática dos conteúdos abordados. A capacitação propõe uma abordagem contínua e adaptável, passível de replicação em outras unidades do IFRO e em demais Institutos Federais com estrutura organizacional semelhante. Assim, o curso consolida-se como uma ferramenta estratégica de valorização e qualificação da gestão pública educacional, promovendo não apenas o desenvolvimento individual dos participantes, mas também o fortalecimento institucional e o atendimento mais eficaz às demandas da sociedade.
Outsourcing Computation: the Minimal Refereed Mechanism
Creators: name: Kong, Yuqing
name: Peikert, Chris
name: Schoenebeck, Grant
name: Tao, Biaoshuai
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computer Science and Game Theory (cs.GT)
subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: We consider a setting where a verifier with limited computation power delegates a resource intensive computation task---which requires a $T\times S$ computation tableau---to two provers where the provers are rational in that each prover maximizes their own payoff---taking into account losses incurred by the cost of computation. We design a mechanism called the Minimal Refereed Mechanism (MRM) such that if the verifier has $O(\log S + \log T)$ time and $O(\log S + \log T)$ space computation power, then both provers will provide a honest result without the verifier putting any effort to verify the results. The amount of computation required for the provers (and thus the cost) is a multiplicative $\log S$-factor more than the computation itself, making this schema efficient especially for low-space computations.
description: 17 pages, 1 figure; WINE 2019: The 15th Conference on Web and Internet Economics
sj-docx-1-qjp-10.1177_17470218221128306 – Supplemental material for Object coding in peripersonal space depends on object ownership
Creators: name: Lenglart, Lucie
name: Cartaud, Alice
name: Quesque, François
name: Sampaio, Adriana
name: Coello, Yann
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-qjp-10.1177_17470218221128306 for Object coding in peripersonal space depends on object ownership by Lucie Lenglart, Alice Cartaud, François Quesque, Adriana Sampaio and Yann Coello in Quarterly Journal of Experimental Psychology
O desenvolvimento de competências gerenciais no Instituto Federal de Rondônia - campus Colorado do Oeste: uma proposta de capacitação gerencial
Creators: name: Mayuma Martins Santana Viana
name: Débora Vargas Ferreira Costa
Publisher: name: Zenodo
Year: 2024

description: O presente produto tecnológico é resultado da dissertação de mestrado profissional em Gestão e Estratégia da Universidade Federal Rural do Rio de Janeiro (UFRRJ), defendida por Mayuma Martins Santana Viana sob orientação da Profa. Dra. Débora Vargas Ferreira Costa. A produção consiste na elaboração de um Curso de Capacitação Gerencial voltado a servidores do Instituto Federal de Educação, Ciência e Tecnologia de Rondônia (IFRO) – campus Colorado do Oeste, com foco no desenvolvimento de competências gerenciais essenciais à atuação de gestores de nível intermediário. Alinhado à linha de pesquisa “Estratégia de Gestão de Pessoas e Organizações” do Programa de Pós-Graduação em Gestão e Estratégia (PPGE/UFRRJ), especialmente ao projeto “Estratégias de Gestão de Pessoas, Liderança Organizacional e Relações de Trabalho”, o curso visa preparar os gestores para liderar equipes de forma eficiente, enfrentar desafios cotidianos e contribuir para o alcance dos objetivos estratégicos institucionais. Com médio grau de inovação, a proposta combina conhecimentos pré-estabelecidos, organizados em quatro eixos temáticos: competências institucionais, comportamentais, funcionais e políticas. A capacitação, com carga horária mínima de 220 horas, integra cursos de curta duração e encontros de compartilhamento de experiências, podendo ser ofertada presencialmente ou a distância. Os recursos didáticos e metodológicos incluem apostilas digitais, oficinas práticas, rodas de conversa e plataformas como a ENAP. O impacto esperado inclui a melhoria do desempenho dos gestores, a elevação da qualidade na prestação de serviços públicos e a promoção de mudanças organizacionais significativas, por meio da aprendizagem experiencial e da aplicação prática dos conteúdos abordados. A capacitação propõe uma abordagem contínua e adaptável, passível de replicação em outras unidades do IFRO e em demais Institutos Federais com estrutura organizacional semelhante. Assim, o curso consolida-se como uma ferramenta estratégica de valorização e qualificação da gestão pública educacional, promovendo não apenas o desenvolvimento individual dos participantes, mas também o fortalecimento institucional e o atendimento mais eficaz às demandas da sociedade.
Statistical Computing 2018 : Abstracts der 50. Arbeitstagung
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: DDC 004 / Data processing & computer science
subject: Bioinformatics; Congresses; Abstracts
subject: Statistics; Computer programs; Congresses; Abstracts
subject: Systems biology; Congresses; Abstracts
subject: Bioinformatik
subject: Statistik
subject: Klassifikation
subject: Datenanalyse

description: Abstracts der 50. Arbeitstagung der Arbeitsgruppen Statistical Computing (GMDS/IBS-DR), Klassifikation und Datenanalyse in den Biowissenschaften (GfKl). 08.07. - 11.07.2018, Schloss Reisensburg (Günzburg)
Adaptive Greedy versus Non-adaptive Greedy for Influence Maximization
Creators: name: Chen, Wei
name: Peng, Binghui
name: Schoenebeck, Grant
name: Tao, Biaoshuai
Publisher: name: arXiv
Year: 2019
Subjects: subject: Social and Information Networks (cs.SI)
subject: FOS: Computer and information sciences

description: We consider the *adaptive influence maximization problem*: given a network and a budget $k$, iteratively select $k$ seeds in the network to maximize the expected number of adopters. In the *full-adoption feedback model*, after selecting each seed, the seed-picker observes all the resulting adoptions. In the *myopic feedback model*, the seed-picker only observes whether each neighbor of the chosen seed adopts. Motivated by the extreme success of greedy-based algorithms/heuristics for influence maximization, we propose the concept of *greedy adaptivity gap*, which compares the performance of the adaptive greedy algorithm to its non-adaptive counterpart. Our first result shows that, for submodular influence maximization, the adaptive greedy algorithm can perform up to a $(1-1/e)$-fraction worse than the non-adaptive greedy algorithm, and that this ratio is tight. More specifically, on one side we provide examples where the performance of the adaptive greedy algorithm is only a $(1-1/e)$ fraction of the performance of the non-adaptive greedy algorithm in four settings: for both feedback models and both the *independent cascade model* and the *linear threshold model*. On the other side, we prove that in any submodular cascade, the adaptive greedy algorithm always outputs a $(1-1/e)$-approximation to the expected number of adoptions in the optimal non-adaptive seed choice. Our second result shows that, for the general submodular diffusion model with full-adoption feedback, the adaptive greedy algorithm can outperform the non-adaptive greedy algorithm by an unbounded factor. Finally, we propose a risk-free variant of the adaptive greedy algorithm that always performs no worse than the non-adaptive greedy algorithm.
description: 26 pages, 0 figure, accepted at JAIR'22: Journal of Artificial Intelligence Research 74 (2022) 303-351; A short version of this paper was accepted at AAAI'20: Thirty-Fourth AAAI Conference on Artificial Intelligence
sj-docx-1-ajs-10.1177_03635465231170699 – Supplemental material for Return to Sport After Anatomic Lateral Ankle Stabilization Surgery for Chronic Ankle Instability: A Systematic Review and Meta-analysis
Creators: name: Li, Yanzhang
name: Su, Tong
name: Hu, Yuelin
name: Jiao, Chen
name: Guo, Qinwei
name: Jiang, Yanfang
name: Jiang, Dong
Publisher: name: SAGE Journals
Year: 2023
Subjects: Orthopaedics
Sports Medicine
Surgery

description: Supplemental material, sj-docx-1-ajs-10.1177_03635465231170699 for Return to Sport After Anatomic Lateral Ankle Stabilization Surgery for Chronic Ankle Instability: A Systematic Review and Meta-analysis by Yanzhang Li, Tong Su, Yuelin Hu, Chen Jiao, Qinwei Guo, Yanfang Jiang and Dong Jiang in The American Journal of Sports Medicine
Additional file 2 of Extracellular vesicles from UTX-knockout endothelial cells boost neural stem cell differentiation in spinal cord injury
Creators: name: Liu, Yudong
name: Luo, Zixiang
name: Xie, Yong
name: Sun, Yi
name: Yuan, Feifei
name: Jiang, Liyuan
name: Lu, Hongbin
name: Hu, Jianzhong
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: Developmental Biology

description: Additional file 2.