cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Data management and wearables in older adults: A systematic review
Creators: name: Gallagher, R
name: Straiton, N
name: Smith, S
name: Alharbi, M
name: Neubeck, L
Publisher: name: Elsevier Ireland Ltd
Year: 2019

description: Background: Wearable trackers as research or clinical tools are increasingly used to support the care of older adults, due to their practicality in self-monitoring and potential to promote healthy lifestyle behaviours. However, there is limited understanding of appropriate data collection and analysis methods in different contexts. Aim: To summarise evidence on wearable data generation and management in older adults, focusing on physical activity (PA), electrocardiogram (ECG), and vital signs monitoring. In addition to examine the accuracy and utility of wearable trackers in the care of older people. Methods: A systematic search of CINAHL, MEDLINE, PubMed and a manual search were conducted. Twenty studies on the use of wearable trackers by older adults met the inclusion criteria. Results: Methodological designs for data collection and analysis were heterogeneous, with diverse definitions of wear and no-wear time, the number and type of valid days, and proprietary algorithms. Wearable trackers had adequate accuracy for measuring step counts, moderate to vigorous physical activity (MVPA), ECG and heart rate (HR), but not for respiratory rate. Participants reported ease of use and had high-level adherence over daily long-term use. Moreover, wearable trackers encouraged users to increase their daily level of physical activity and decrease waist circumference, facilitating atrial fibrillation (AF)diagnoses and predicting length of stay. Conclusion: Wearable trackers are multi-dimensional technologies offering a viable and promising approach for sustained and scaled monitoring of older people's health. Frameworks and/or guidelines, including standards for the design, data management and application of use specifically for older adults, are required to enhance validity and reliability.
title: Rheumabus on Tour
Creators: name: Puchner, Rudolf
name: Schaffer, Gertraud
name: Sautner, Judith
name: Stamm, Tanja
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Rheumatologische Versorgung ist immer noch regional unterschiedlich verfügbar. Auf Initiative der Österreichischen Rheumaliga (Patientenliga) und der Österreichischen Gesellschaft für Rheumatologie und Rehabilitation (ÖGR) entstand das Projekt, 13 Jahre nach einem[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Precision measurements of threshold chargino production
Creators: name: Berger, M. S.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We analyze the prospects at a muon collider for measuring chargino masses in the $μ^+μ^-\to \tildeχ^+\tildeχ^-$ processes in the threshold region. We find that a measurement of the lightest chargino mass to better than 200 MeV is possible with 100~fb$^{-1}$ luminosity. The muon sneutrino mass can also be simultaneously measured to a few GeV.
description: 7 pages, 3 figure, Presented at the Workshop on Physics at the First Muon Collider and at the Front End of a Muon Collider, November 6-9, 1997, Fermi National Accelerator Laboratory
Sorbus lonetalensis – eine neue Mehlbeere aus Baden-Württemberg
Creators: name: Hammel, Steffen
name: Haynold, Bernd
Publisher: name: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
Year: 2015

description: Über den Fund eines neuen Sorbus hybrida agg.-Bastardes aus Süddeutschland wird berichtet. Seine intermediären morphologischen Eigenschaften werden detailliert vorgestellt, der Bastard als Sorbus lonetalensis beschrieben. Die Verschiedenheiten zu verwandten Taxa werden herausgearbeitet. Gesichtspunkte des Naturschutzes werden diskutiert.
description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg, Bd. 171 (2015): Jahreshefte der Gesellschaft für Naturkunde in Württemberg, 171. Jahrgang
Switchable peptide-equipped protein/cucurbit[7]uril supramolecular assembly for targeted drug delivery
Creators: name: Yan, Danhong
name: Miao, Xiangyang
name: Ma, Ronghua
name: Yao, Huashan
name: Li, Jinlong
name: Cao, Ya
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Herein, we develop a switchable peptide-equipped protein/cucurbit[7]uril (CB[7]) supramolecular assembly as novel targeted drug vector. Specifically, bovine serum albumin (BSA) is used to interact with CB[7], serving as the core of drug vector. Then, a peptide shield layer is formed on the surface of BSA/CB[7], yielding peptide-equipped supramolecular assembly (Pep@BSA@CB[7]). The equipped peptide shield layer is composed of switchable peptide probes consisting of a polycationic cell-penetrating peptide (CPP) motif, a polyanionic motif and a linking motif, and therefore provides a variety of desirable properties. First, the CPP motif displays excellent cell penetration ability and can facilitate internalisation of the drug vector. Secondly, the polyanionic motif performs intramolecular electrostatic interaction with CPP motif and thereby can reduce non-targeted delivery towards normal cells. Thirdly, the linking motif can be specifically cleaved by matrix metalloproteinases 2 that is up-regulated in tumour microenvironment, thus enabling precise cancer-targeting. As a consequent, Pep@BSA@CB[7] can serve as a promising drug vector that exhibits superior targeting ability and high uptake efficiency towards cancer cells, which may be of great potential in cancer-targeted treatment.
Ploidie-Bestimmung baden-württembergischer Bastard-Mehlbeeren
Creators: name: Hammel, Steffen
name: Haynold, Bernd
name: Gregor, Thomas
name: Paule, Juraj
Publisher: name: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
Year: 2015

description: Hybriden der Sorbus latifolia- und der Sorbus hybrida-Aggregate sind aus Südwestdeutschland (Baden-Württemberg, Main-Tauber-Gebiet, Ostalb) nachgewiesen. Mit Hilfe der Durchflusszytometrie wurde die relative DNA-Menge in somatischen Zellkernen von 19 Bastard-Mehlbeeren bestimmt, welche man den Ploidiestufen zuordnen konnte. Untersuchte Sorbus-Pflanzen erwiesen sich als tri- oder tetraploid.
description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg, Bd. 171 (2015): Jahreshefte der Gesellschaft für Naturkunde in Württemberg, 171. Jahrgang
Sorbus seyboldiana – eine neue Mehlbeere aus Baden-Württemberg und Bayern
Creators: name: Hammel, Steffen
name: Haynold, Bernd
Publisher: name: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
Year: 2015

description: Sorbus seyboldiana wird neu beschrieben. Die Hauptverbreitung liegt derzeit zwischen den Gemeinden Neubrunn-Böttigheim (Bayern) und Werbach (Baden- Württemberg). Die Art wird mit einer Fotografie des Typus-Beleges und durch Fotografien lebender Pflanzen illustriert. Die wichtigen Erkennungsmerkmale werden vorgestellt und Unterscheidungsmerkmale ähnlicher oder in der Nähe vorkommender Arten kurz beschrieben. Ferner wird auf die ökologischen Präferenzen der Seybold-Mehlbeere und auf Naturschutzaspekte eingegangen.
description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg, Bd. 171 (2015): Jahreshefte der Gesellschaft für Naturkunde in Württemberg, 171. Jahrgang
title: Leitliniengerechte Scorebestimmung von Rheumaerkrankungen mit dem Tablet – Chancen und Risiken
Creators: name: Detert, Jacqueline
name: Detert, Markus
name: Schröder, Ralf
name: Brinkhues, Sven
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die effiziente leitliniengerechte Scorebestimmung (Krankheitsaktivitätsscores, Patienten berichtete Parameter, Schmerz- und psychologische Scores) von Rheumaerkrankungen bildet eine unabdingbare Voraussetzung für die qualitativ hochwertige ambulante Versorgung von Patienten. Ziel[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Bestand und Genese des Herbariums Hegelmaier (STU). Dargestellt am Beispiel der Gattung Hieracium (Asteraceae) unter besonderer Berücksichtigung der Typus-Belege
Creators: name: Gottschlich, Günter
Publisher: name: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
Year: 2015

description: 781 Belege der Gattung Hieracium aus dem Herbarium F. Hegelmaier (STU) wurden revidiert. Sie verteilen sich auf 187 Arten und 278 Unterarten. 41 Typus-Belege konnten ermittelt werden. Das Hieracium-Herbar ist reich an Exsikkatenmaterial. 82 von 139 Sammlern darin sind für das Herbarium STU noch nicht dokumentiert.
description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg, Bd. 171 (2015): Jahreshefte der Gesellschaft für Naturkunde in Württemberg, 171. Jahrgang
Kartierung und digitale, geografische Darstellung der Vorkommen des Schwarzen Streifenfarns (Asplenium adiantum-nigrum L.) an Trockensteinmauern in Tübingen (Baden-Württemberg)
Creators: name: Geffert, Johannes
name: Engelhardt, Martin
name: Luick, Rainer
Publisher: name: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
Year: 2015

description: Die Arbeit befasst sich mit der Digitalisierung und Darstellung von Vorkommen des Schwarzen Streifenfarns (Asplenium adiantum-nigrum L.) in Trockenmauern in Tübingen. Im Detail wurden in drei Untersuchungsgebieten (Neuhalde, Ebenhalde und Sandklinge, Gemarkungen Tübingen und Hagelloch) die Mauern und die Farnbestände aufgenommen. Die einzelnen Vorkommen wurden mit statistischen Verfahren populationsökologisch charakterisiert und verglichen. Für das Naturdenkmal „Schwarzer Streifenfarn“ wurden Vergleiche zu den bisherigen Arbeiten zum Streifenfarn (Voigt 1995, 1996, 1997, 1999, und 2003) gezogen. Die Ergebnisse zeigen, dass die Population der Farnpflanzen im Gebiet der Ebenhalde deutlich kleiner und weniger vital ist als die in den Gebieten der Neuhalde und Sandklinge. Ein Zusammenhang zwischen der Anzahl der Farnpflanzen und der Beschattung konnte nicht eindeutig festgestellt werden. Insgesamt sind die Populationen des Schwarzen Streifenfarns in Tübingen als stabil zu bezeichnen. Empfehlungen zur Erhaltung dieser gefährdeten und in Deutschland rückläufigen Art werden gegeben: Ein regelmäßiges Monitoring ist empfehlenswert, um das Wuchsverhalten weiter beobachten und um der aufkommenden Sukzession frühzeitig entgegenwirken zu können. Schlüsselwörter: Schwarzer Streifenfarn, Asplenium adiantum-nigrum, Population, Trockenmauern, Tübingen, Pflegemaßnahmen.
description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg, Bd. 171 (2015): Jahreshefte der Gesellschaft für Naturkunde in Württemberg, 171. Jahrgang
Magnetic sensitivity in the wing scattering polarization signals of the hydrogen Lyman-alpha line of the solar disk radiation
Creators: name: Ballester, Ernest Alsina
name: Belluzzi, Luca
name: Bueno, Javier Trujillo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The linear polarization produced by scattering processes in the hydrogen Lyman alpha line of the solar disk radiation is a key observable for probing the chromosphere-corona transition region (TR) and the underlying chromospheric plasma. While the line-center signal encodes information on the magnetic field and three-dimensional structure of the TR, the sizable scattering polarization signals that the joint action of partial frequency redistribution (PRD) and J-state interference produce in the Lyman alpha wings have generally been thought to be sensitive only to the thermal structure of the solar atmosphere. Here we show that the wings of the Q/I and U/I scattering polarization profiles of this line are actually sensitive to the presence of chromospheric magnetic fields, with strengths similar to those that produce the Hanle effect in the line core (i.e., between 5 and 100 gauss, approximately). In spite of the fact that the Zeeman splitting induced by such weak fields is very small compared to the total width of the line, the magneto-optical effects that couple the transfer equations for Stokes Q and U are actually able to produce sizable changes in the Q/I and U/I wings. The theoretical results presented here further expand the diagnostic content of the unprecedented spectropolarimetric observations provided by the Chromospheric Lyman-Alpha Spectropolarimeter (CLASP).
description: Accepted for publication in the Astrophysical Journal. 13 pages, 7 figures, 3 appendices
De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework
Creators: name: Filizola, M
name: DiBerto, J.F
name: Jin, J
name: Lamim Ribeiro, J.M
name: Provasi, D
name: Qiu, X
name: Salas-Estrada, L
name: Huang, X.-P
name: Roth, B.L
name: Kaniskan, H.U
Publisher: name: American Chemical Society
Year: 2023

description: Likely effective pharmacological interventions for the treatment of opioid addiction include attempts to attenuate brain reward deficits during periods of abstinence. Pharmacological blockade of the κ-opioid receptor (KOR) has been shown to abolish brain reward deficits in rodents during withdrawal, as well as to reduce the escalation of opioid use in rats with extended access to opioids. Although KOR antagonists represent promising candidates for the treatment of opioid addiction, very few potent selective KOR antagonists are known to date and most of them exhibit significant safety concerns. Here, we used a generative deep-learning framework for the de novo design of chemotypes with putative KOR antagonistic activity. Molecules generated by models trained with this framework were prioritized for chemical synthesis based on their predicted optimal interactions with the receptor. Our models and proposed training protocol were experimentally validated by binding and functional assays.
The effects of social and emotional learning on student well-being.
Creators: name: Mahad, Muhudin Omar
Publisher: name: Zenodo
Year: 2025
Subjects: social and emotional learning
student well-being

description: ABSTRACT

The purpose of this study is To make assessment The effects of social and emotional learning on student well-being. The overall aim of this study was guided by the very important objectives: To defines the impact of job enrichment on employee retention to the business in some selected businesses in Mogadishu, Somalia. The study was conducted from January 2024 to June 2024. This research was used descriptive design, through questionnaire design to describe the characteristics and correlation to measure central tendency of matters of the questionnaire.  The total number of population in the study was employed 63 intellectual in the Mogadishu City as a case study since the time and cost could not allow accessing all the media sectors in the City of Mogadishu. 54 participants of sample size of different gender who have been selected from the population departments within the sectors of this scope in Mogadishu. These participants have been chosen according to the possibility of getting accurate and reliable information. The sampling procedure of this study was non-probability sampling especially purposive sampling to conduct the research, and also to consider the significance of research reality. This research study was collected primarily data using questionnaires. In this study quantitative data analysis was used. The analysis was carried out with the use of help Statistical Package for Social Sciences (SPSS version 20), that was measured the use of in Mogadishu, Benadir, Somalia. The major findings that supported the argument include the objectives and even the dependent variable of the study. For instance the questions of the first objective generally result a common concept of that motivation on employee retention to the business in some selected metropolis in Mogadishu, Somalia.
Experimental validation of an aeroelastic reduced order model dedicated to high aspect ratio flexible composite wing
Creators: name: KIRSCH, Bertrand
name: MONTAGNIER, Olivier
name: BENARD, Emmanuel
name: FAURE, Thierry M.
Publisher: name: Proceedings of the 8th European Conference for Aeronautics and Space Sciences. Madrid, Spain, 1-4 july 2019
Year: 2019
Subjects: AEROELASTICITY
COMPOSITES
WIND TUNNEL
NUMERICAL SIMULATION
UAV

description: The enhancement of high altitude drone endurance compels to design very flexible high-aspect-ratio composite airframe vulnerable to destructive fluid/structure interaction like flutter or torsional divergence. Extensive research has been conducted to increase critical speed without being at the expense of weight balance. One of the promising solutions is the aeroelastic tailoring which consists in a specific configuration of laminated composite layup. The present work uses an aeroelastic reduced order model, namely GEBTAero, suitable for the non linear anisotropic behavior of this kind of composite wing, able to quickly compute aeroelastic critical speeds. Particular focus is put on a wind tunnel test campaign conducted on a set of three-ply composite flexible plates, in order to assess the accuracy of GEBTAero.
Decreased Susceptibility of Marginal Odds Ratios to Finite-sample Bias
Creators: name: Richardson D.B
name: Ross R.K
name: Cole S.R
Publisher: name: Lippincott Williams and Wilkins
Year: 2021

description: Parameters representing adjusted treatment effects may be defined marginally or conditionally on covariates. The choice between a marginal or covariate-conditional parameter should be driven by the study question. However, an unappreciated benefit of marginal estimators is a reduction in susceptibility to finite-sample bias relative to the unpenalized maximum likelihood estimator of the covariate-conditional odds ratio (OR). Using simulation, we compare the finite-sample bias of different marginal and conditional estimators of the OR. We simulated a logistic model to have 15 events per parameter and two events per parameter. We estimated the covariate-conditional OR by maximum likelihood with and without Firth's penalization. We used three estimators of the marginal OR: g-computation, inverse probability of treatment weighting, and augmented inverse probability of treatment weighting. At 15 events per parameter, as expected, all estimators were effectively unbiased. At two events per parameter, the unpenalized covariate-conditional estimator was notably biased but penalized covariate-conditional and marginal estimators exhibited minimal bias.
In-flight transition of a Dual-Bell nozzle - transonic vs. supersonic transition
Creators: name: BOLGAR, Istvan
name: SCHARNOWSKI, Sven
name: KAHLER, Christian J.
Publisher: name: Proceedings of the 8th European Conference for Aeronautics and Space Sciences. Madrid, Spain, 1-4 july 2019
Year: 2019
Subjects: AEROSPACE PROPULSION
AERODYNAMICS
NOZZLES
LAUNCH VEHICLE DESIGN
SPACE PROPULSION

description: The interaction between an external flow with a Dual-Bell nozzle flow is investigated experimentally with particle image velocimetry and schlieren shadowgraphy. Previous results showed that the interaction of a supersonic external flow and the jet plume triggers the flip-flop effect. The current results at transonic free-stream conditions show that transition occurs without retransition, eliminating flip-flop. However, in sea level mode at transonic free-stream conditions, nozzle screeching is identified to occur at S r s 0.3. This is most likely triggered by the separated flow in the nozzle extension, which has to be addressed in future research on Dual-Bell nozzles.
Program ekološkega žlahtnjenja sort krompirja na Kmetijskem inštitutu Slovenije v okviru projekta ECOBREED
Creators: name: Dolničar, Peter
name: Blatnik, Eva
name: Meglič, Vladimir
Publisher: name: Zenodo
Year: 2021
Subjects: potato, organic breeding, organic varieties, late blight resistance, PVY resitance

description: Describes the establishment of organic potato breeding programe at the Kmetijski inštitut Slovenije within the project Ecobreeed, and the results of two year selection.
The effect of the job satisfaction on performance of teachers at some schools in Afgoi-Lower shabelle-Somalia.
Creators: name: Mohamud, Alim Ibrahim
Publisher: name: Zenodo
Year: 2025
Subjects: job satisfaction
teachers at some schools

description: ABSTRACT

Background: This section discovers the research result and findings derived from the distributed questionnaires.

The main purpose of this study was to explore the effect of job satisfaction on performance of teachers at some selected schools in at some selected schools in Afgoi district, Lower Shabelle- Somalia.

The study had four objectives.

First objective to identify the effect of Motivation on performance of teachers at some selected schools in Lower Shabelle - Somalia, Second objective was to identify  the effect of compensation on performance of teachers at some selected schools in Lower Shabelle-Somalia, third objective was to investigate the effect of working environment on performance of teachers fourth objective was To determine relationship between the job satisfaction and performance of teachers Since a teacher is a role model for the students, job satisfaction and eventually the performance of a teacher becomes very vital in the field of education.

Thus, the researcher felt the need to investigate the job satisfaction and performance of teachers in different categories of schools following different systems of education.

Thus, this study concentrates on the effect of job satisfaction on performance of teachers at some selected schools in Lower Shabelle-Somalia.

Method: descriptive, Target population: 80 respondents of selected schools in Lower Shabelle Supervisors, headmasters, and teachers Selected from four schools (Al-Qasimi primary and secondary school, Abi Musa primary and secondary school, Afgoi primary and secondary school and Dolawe primary and secondary school) Sample: 67 responders, Sample procedure: probability sampling, Instrument:

Result: As summarized in tables 4.1-4.6. Concerning age, all the respondents were between 20-50 years and thus mature enough to be in a position to contribute information about the effect of job satisfaction on performance of teachers at some selected schools in Lower Shabelle.  Spss Based on findings in objective one carries four statements which scored the rating of agree “Good” which indicates by the value it is mostly agreed in the effect of Motivation on performance of teachers.

Conclusion:

this study focused and examined on the effect of job satisfaction on teachers of performance at some selected schools in Lower Shabelle.
Elastic waves simulation and damping characterization on composite structures for structural health monitoring applications
Creators: name: SANCHEZ IGLESIAS, Fernando
name: BRONCANO GARCIA, Pablo
name: TEJERINA HERNANZ, Ruben
name: FERNANDEZ LOPEZ, Antonio
name: IGLESIAS VALLEJO, Manuel
Publisher: name: Proceedings of the 8th European Conference for Aeronautics and Space Sciences. Madrid, Spain, 1-4 july 2019
Year: 2019
Subjects: STRUCTURES
COMPOSITES
MODELLING

description: A study based on the numerical simulations of the propagation of elastic waves on composite panels has been performed in order to support the development of a Structural Health Monitoring system. The simulations are correlated with a number of active interrogation tests, which have been performed in both a simplified composite plate and a representative aircraft structure. Additionally passive tests of very low energy impacts have also been used to estimate a damping coefficient to use in the simulations. The results and validation of the simulations are discussed in this paper.
Defect compensation in formamidinium–caesium perovskites for highly efficient solar mini-modules with improved photostability
Creators: name: Huang J
name: Chen S
name: Zhao J
name: Xu S
name: Xiao X
name: Deng Y
Publisher: name: Nature Research
Year: 2021

description: Formamidinium–caesium mixed-cation perovskites have shown better thermal stability than their methylammonium-containing counterparts but they suffer from photoinstability induced by iodide migration and phase segregation. Here we improve their photostability by adding slightly excessive AX (at a molar percentage of 0.25% to Pb2+ ions), where A is formamidinium or caesium and X is iodine. The excessive AX does not improve the initial solar cell efficiency. It compensates iodide vacancies and suppresses ion migration and defects generation during long-term illumination by around tenfold compared with AX-deficient devices. Consequently, generation of hole traps and phase segregation is impeded, with the former limiting solar cell efficiency after degradation. The perovskite mini-modules reached a certified stabilized efficiency of 18.6% with an aperture area of ~30 cm2, corresponding to an active area efficiency of 20.2%. The mini-module maintains 93.6% of the initial efficiency after continuous operation under 1 sun illumination for >1,000 h at 50 ± 5 °C in air.
MOESM1 of Synergistic modulation of signaling pathways to expand and maintain the bipotency of human hepatoblasts
Creators: name: Pan, Tingcai
name: Chen, Yan
name: Zhuang, Yuanqi
name: Yang, Fan
name: Xu, Yingying
name: Tao, Jiawang
name: You, Kai
name: Wang, Ning
name: Wu, Yuhang
name: Lin, Xianhua
name: Wu, Feima
name: Liu, Yanli
name: Li, Yingrui
name: Wang, Guodong
name: Li, Yin-xiong
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Supporting information.
PlanetaryTransits and Oscillation of Stars (PLATO) Focal Plane Assembly (FPA): Preliminary Model Philosophy and Prototype test results.
Creators: name: VERA, Isabel
name: BALADO, Ana
name: PAJAS, Miriam
name: CERRUTI, Chiara
name: ALCACERA, M Angeles
name: RAMOS, Gonzalo
name: VALVEDE GUIJARRO, Angel Luis
name: GONZALEZ LLAMAZARES, Laura
name: CATALAN, Irene
name: MANJON, Andres
name: PEREZ, Elena
name: MUNOZ, David
name: BARRADO, David
name: MAS, Miguel
Publisher: name: Proceedings of the 8th European Conference for Aeronautics and Space Sciences. Madrid, Spain, 1-4 july 2019
Year: 2019
Subjects: AEROSPACE SYSTEMS
PAYLOAD
SYSTEMS
STRUCTURES
VERIFICATION AND VALIDATION

description: PLATO (PLAnetary Transits and Oscillations of stars) is an ESA mission, which is dedicated to the detection and characterization of terrestrial exo-planets. In the baseline design, it is planned to mount 26 cameras in the same instrument bench. Each camera consists on a telescope, the focal plane assembly (FPA) and the detector electronics. This amount of cameras that has to be manufactured, integrated and tested at the same time makes this mission an industrialization process. This paper explains the approach of the initial model philosophy used and the tests results of the FPA prototype.
Observation of Topological Photocurrents in the Chiral Weyl Semimetal RhSi
Creators: name: Rees, Dylan
name: Manna, Kaustuv
name: Lu, Baozhu
name: Morimoto, Takahiro
name: Borrmann, Horst
name: Felser, Claudia
name: Moore, J. E.
name: Torchinsky, Darius H.
name: Orenstein, J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Weyl semimetals are crystals in which electron bands cross at isolated points in momentum space. Associated with each crossing point (or Weyl node) is an integer topological invariant known as the Berry monopole charge. The discovery of new classes of Weyl materials is driving the search for novel properties that derive directly from the Berry charge. The circular photogalvanic effect (CPGE), whereby circular polarized light generates a current whose direction depends on the helicity of the absorbed photons, is a striking example of a macroscopic property that emerges from Weyl topology. Recently, it was predicted that the rate of current generation associated with optical transitions near a Weyl node is proportional to its monopole charge and independent of material-specific parameters. In Weyl semimetals that retain mirror symmetry this universal photogalvanic current is strongly suppressed by opposing contributions from energy equivalent nodes of opposite charge. However, when all mirror symmetries are broken, as in chiral Weyl systems, nodes with opposite topological charge are no longer degenerate, opening a window of photon energies where the topological CPGE can emerge. In this work we test this theory through measurement of the photon-energy dependence of the CPGE in the chiral Weyl semimetal RhSi. The spectrum is fully consistent with a topological CPGE, as it reveals a response in a low-energy window that closes at 0.65 eV, in quantitative agreement with the theoretically-derived bandstucture.
description: 33 pages, 4 + 6 figures
Defect engineering in wide-bandgap perovskites for efficient perovskite–silicon tandem solar cells
Creators: name: Luther J.M
name: Larson B.W
name: Yu Z
name: Holman Z.C
name: Xiao X
name: Yu Z.J
name: Alasfour A
name: Ni Z
name: Chen B
name: Yang G
name: Huang J
Publisher: name: Nature Research
Year: 2022

description: Wide-bandgap (WBG) mixed-halide perovskites show promise of realizing efficient tandem solar cells but at present suffer from large open-circuit voltage loss and the mechanism is still unclear. Here we show that WBG perovskites with iodide–bromide compositions have an increased concentration of deep traps induced by iodide interstitials, which limits performance of WBG perovskite cells. We employ tribromide ions to suppress the iodide interstitial formation and thus reduce charge recombination in bladed WBG perovskite films of Cs0.1FA0.2MA0.7Pb(I0.85Br0.15)3. The 1-µm-thick opaque WBG perovskite solar cells have an efficiency of 21.9%, a small open-circuit voltage deficit of 0.40 V and a large fill factor of 83%. The efficiency of the best-performing monolithic perovskite–silicon tandem cell using this perovskite reaches 28.6%. The tribromide addition also suppresses light-induced phase segregation in WBG perovskites and thus enhance device stability. Encapsulated tandem cells maintain 93% of their initial efficiency after operation for 550 h.
Identification, methylation profiling, and expression analysis of stress-responsive cytochrome P450 genes in rice under abiotic and phytohormones stresses
Creators: name: Waseem, Muhammad
name: Huang, Feiyan
name: Wang, Qiyu
name: Aslam, Mehtab Muhammad
name: Abbas, Farhat
name: Ahmad, Fiaz
name: Ashraf, Umair
name: Hassan, Waseem
name: Fiaz, Sajid
name: Ye, Xianwen
name: Yu, Lei
name: Ke, Yanguo
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The cytochrome P450 (CYP) is a large and complex eukaryotic gene superfamily with enzymatic activities involved in several physiological and regulatory processes. As an objective, an in-silico genome-wide DNA methylation (5mC) analysis was performed in rice (Oryza sativa cv. Zhonghua11), and the epigenetic role of CYPs in two abiotic stresses was observed. Being a stable representative mark, DNA-methylation alters the gene expression under stressful environmental conditions. Rice plants under salinity and drought stresses were analyzed through MeDIP-chip hybridization, and 14 unique genes of the CYP family were identified in the rice genome with varying degrees of methylation. The gene structure, promoter sequences, and phylogenetic analysis were performed. Furthermore, the responses of CYPs to various abiotic stresses, including salinity, drought, and cold were revealed. Similarly, the expression profile of potential CYPs was also investigated under various phytohormone stresses, which revealed the potential involvement of CYPs to hormone regulations. Overall, the current study provides evidence for CYP’s stress regulation and fundamental for further characterization and understanding their epigenetic roles in gene expression regulation and environmental stress regulation in higher plants.
Dual heterogeneous structure facilitating an excellent strength-ductility combination in an additively manufactured multi-principal-element alloy
Creators: name: Huang, Jing
name: Li, Wanpeng
name: He, Junyang
name: Zhou, Rui
name: Chou, Tzu-Hsiu
name: Yang, Tao
name: Liu, Chain-Tsuan
name: Zhang, Weidong
name: Liu, Yong
name: Huang, Jacob C.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Plant Biology

description: The (FeCoNi)86Ti7Al7 multi-principal-element alloy with a dual heterogeneous microstructure was successfully fabricated by selective laser melting, exhibiting an excellent combination of strength (ultimate tensile strength, 1085.2 ± 23.2 MPa) and ductility (30.5 ± 2.6%). It is evidenced that the joint effects of the hetero-deformation induced hardening from grains with heterogeneous geometrically necessary dislocations densities, in-situ formed B2 phase, and the coherent precipitation hardening from in-situ formed nano L12 phase were responsible for the strength. This work sheds light on the feasibility of simplifying the production of multi-mechanism strengthened alloys within one step and paves a new avenue to produce high-performance complex-shaped components. (FeCoNi)86Ti7Al7 multi-principal-element alloy exhibiting heterogeneity on the grains structure and in-situ precipitation was successfully fabricated by selective laser melting. It shows both good tensile strength and ductility.
Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (Tak-003)
Creators: name: Young E.F
name: Henein S.R
name: Baric R.S
name: Stoops M.J
name: de Silva A.M
name: White L.J
name: Adams E.C
Publisher: name: Public Library of Science
Year: 2021

description: The four dengue virus serotypes (DENV1-4) infect several hundred million people each year living in tropical and sub-tropical regions. Clinical development of DENV vaccines is difficult because immunity to a single serotype increases risk of severe disease during a second infection with a new serotype. Leading vaccines are based on tetravalent formulations to induce simultaneous and balanced protective immunity to all 4 serotypes. TAK-003 is a tet-ravalent live attenuated dengue vaccine candidate developed by Takeda Vaccines Inc, which is currently being evaluated in phase 3 efficacy trials. Here, we use antibody depletion methods and chimeric, epitope transplant DENVs to characterize the specificity of neutralizing antibodies in dengue-naïve adults and non-human primates immunized with TAK-003. Our results demonstrate that TAK-003 induced high levels of DENV2 neutralizing antibodies that recognized unique (type-specific) epitopes on DENV2. In contrast, most vaccinated subjects developed lower levels of DENV1, DENV3 and DENV4 neutralizing antibodies that mainly targeted epitopes that were conserved (cross-reactive) between serotypes.
Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders
Creators: name: Geschwind D.H
name: Sullivan P.F
Publisher: name: Cell Press
Year: 2019

description: Studies of the genetics of psychiatric disorders have become one of the most exciting and fast-moving areas in human genetics. A decade ago, there were few reproducible findings, and now there are hundreds. In this review, we focus on the findings that have illuminated the genetic architecture of psychiatric disorders and the challenges of using these findings to inform our understanding of pathophysiology. The evidence is now overwhelming that psychiatric disorders are “polygenic”—that many genetic loci contribute to risk. With the exception of a subset of those with ASD, few individuals with a psychiatric disorder have a single, deterministic genetic cause; rather, developing a psychiatric disorder is influenced by hundreds of different genetic variants, consistent with a polygenic model. As progressively larger studies have uncovered more about their genetic architecture, the need to elucidate additional architectures has become clear. Even if we were to have complete knowledge of the genetic architecture of a psychiatric disorder, full understanding requires deep knowledge of the functional genomic architecture—the implicated loci impact regulatory processes that influence gene expression and the functional coordination of genes that control biological processes. Following from this is cellular architecture: of all brain regions, cell types, and developmental stages, where and when are the functional architectures operative? Given that the genetic architectures of different psychiatric disorders often strongly overlap, we are challenged to re-evaluate and refine the diagnostic architectures of psychiatric disorders using fundamental genetic and neurobiological data. Genetic and genomic approaches provide new layers of insights toward the study, diagnosis, and treatment of complex psychiatric disorders
Understanding depletion forces beyond entropy
Creators: name: Bechinger, C.
name: Rudhardt, D.
name: Leiderer, P.
name: Roth, R.
name: Dietrich, S.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: The effective interaction energy of a colloidal sphere in a suspension containing small amounts of non-ionic polymers and a flat glass surface has been measured and calculated using total internal reflection microscopy (TIRM) and a novel approach within density functional theory (DFT), respectively. Quantitative agreement between experiment and theory demonstrates that the resulting repulsive part of the depletion forces cannot be interpreted entirely in terms of entropic arguments but that particularly at small distances ($\lesssim$ 100 nm) attractive dispersion forces have to be taken into account.
A non-Abelian twist to integer quantum Hall states
Creators: name: Lopes, Pedro L. S.
name: Quito, V. L.
name: Han, Bo
name: Teo, Jeffrey C. Y.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Through a theoretical coupled wire model, we construct strongly correlated electronic \emph{integer} quantum Hall states. As a distinguishing feature, these states support electric and thermal Hall transport violating the Wiedemann-Franz law as $\left(κ_{xy}/σ_{xy}\right)/\left[\left(π^{2}k_{B}^{2}T\right)/3e^{2}\right]<1$.We propose a new Abelian incompressible fluid at filling $ν=16$ that supports a bosonic chiral $(E_{8})_{1}$ conformal field theory at the edge and is intimately related to topological paramagnets in (3+1)D. We further show that this topological phase can be partitioned into two non-Abelian quantum Hall states at filling $ν=8$, each carrying bosonic chiral $(G_{2})_{1}$ or $(F_{4})_{1}$ edge theories, and hosting Fibonacci anyonic excitations in the bulk. Finally, we discover a new notion of particle-hole conjugation based on the $E_{8}$ state that relates the $G_{2}$ and $F_{4}$ Fibonacci states.
description: 12 pages. 3 figures
Search for Anomaly at High x in Polarized Deep Inelastic Scattering Data
Creators: name: Wislicki, Wojciech
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: An idea of possible anomalous contribution of non-perturbative origin to the nucleon spin was examined by analysing data on spin asymmetries in polarized deep inelastic scattering of leptons on nucleons. The region of high Bjorken x was explored. It was shown that experimental data available at present do not evidence for this effect.
description: Submitted to Mod.Phys.Lett. A
Resumen de la tesis doctoral Arquitectura, geometría y paisaje en la dinastía Qing y el japón Tokugawa
Creators: name: Ramírez-Juidías, Emilio
Publisher: name: Zenodo
Year: 2011

description: Esta tesis es una contribución al diseño arquitectónico y del paisaje en Asia Oriental desde mediados del siglo XVII hasta principios del siglo XX, período que coincide con una de las aportaciones más valiosas de los misioneros jesuitas durante la relación mutua que mantuvo la Compañía de Jesús y la Corte Imperial China, lo que dio lugar a un cambio relevante a la hora de pensar la arquitectura.
title: Amphiregulin attenuates lupus nephritis via suppression of pro-inflammatory T-cell functions in an animal model of SLE
Creators: name: Melderis, Simon
name: Warkotsch, Matthias
name: Hagenstein, Julia
name: Herrnstadt, Georg R.
name: Tiegs, Gisa
name: Steinmetz, Oliver M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Background: Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and plays a role in development, tissue homeostasis and tumorigenesis. Recently, however, AREG has also emerged as novel player in immunity. Interestingly, AREG expression was shown to be one of the most highly upregulated[for full text, please go to the a.m. URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Nonequilibrium phase transitions induced by multiplicative noise: effects of self-correlation
Creators: name: Mangioni, S. E.
name: Deza, R. R.
name: Toral, R.
name: Wio, H.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: A recently introduced lattice model, describing an extended system which exhibits a reentrant (symmetry-breaking, second-order) noise-induced nonequilibrium phase transition, is studied under the assumption that the multiplicative noise leading to the transition is colored. Within an effective Markovian approximation and a mean-field scheme it is found that when the self-correlation time of the noise is different from zero, the transition is also reentrant with respect to the spatial coupling D. In other words, at variance with what one expects for equilibrium phase transitions, a large enough value of D favors disorder. Moreover, except for a small region in the parameter subspace determined by the noise intensity and D, an increase in the self-correlation time usually preventsthe formation of an ordered state. These effects are supported by numerical simulations.
description: 15 pages. 9 figures. To appear in Phys.Rev.E
Carnegie Supernova Project-II: The Near-infrared Spectroscopy Program
Creators: name: Hsiao, E. Y.
name: Phillips, M. M.
name: Marion, G. H.
name: Kirshner, R. P.
name: Morrell, N.
name: Sand, D. J.
name: Burns, C. R.
name: Contreras, C.
name: Hoeflich, P.
name: Stritzinger, M. D.
name: Valenti, S.
name: Anderson, J. P.
name: Ashall, C.
name: Baltay, C.
name: Baron, E.
name: Banerjee, D. P. K.
name: Davis, S.
name: Diamond, T. R.
name: Folatelli, G.
name: Freedman, Wendy L.
name: Förster, F.
name: Galbany, L.
name: Gall, C.
name: González-Gaitán, S.
name: Goobar, A.
name: Hamuy, M.
name: Holmbo, S.
name: Kasliwal, M. M.
name: Krisciunas, K.
name: Kumar, S.
name: Lidman, C.
name: Lu, J.
name: Nugent, P. E.
name: Perlmutter, S.
name: Persson, S. E.
name: Piro, A. L.
name: Rabinowitz, D.
name: Roth, M.
name: Ryder, S. D.
name: Schmidt, B. P.
name: Shahbandeh, M.
name: Suntzeff, N. B.
name: Taddia, F.
name: Uddin, S.
name: Wang, L.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Shifting the focus of Type Ia supernova (SN Ia) cosmology to the near-infrared (NIR) is a promising way to significantly reduce the systematic errors, as the strategy minimizes our reliance on the empirical width-luminosity relation and uncertain dust laws. Observations in the NIR are also crucial for our understanding of the origins and evolution of these events, further improving their cosmological utility. Any future experiments in the rest-frame NIR will require knowledge of the SN Ia NIR spectroscopic diversity, which is currently based on a small sample of observed spectra. Along with the accompanying paper, Phillips et al. (2018), we introduce the Carnegie Supernova Project-II (CSP-II), to follow up nearby SNe Ia in both the optical and the NIR. In particular, this paper focuses on the CSP-II NIR spectroscopy program, describing the survey strategy, instrumental setups, data reduction, sample characteristics, and future analyses on the data set. In collaboration with the Harvard-Smithsonian Center for Astrophysics (CfA) Supernova Group, we obtained 661 NIR spectra of 157 SNe Ia. Within this sample, 451 NIR spectra of 90 SNe Ia have corresponding CSP-II follow-up light curves. Such a sample will allow detailed studies of the NIR spectroscopic properties of SNe Ia, providing a different perspective on the properties of the unburned material, radioactive and stable nickel produced, progenitor magnetic fields, and searches for possible signatures of companion stars.
description: 20 pages, 7 figures, accepted for publication in PASP
title: Vergleichende Analyse von Biologika-Effekten auf IL-17A- und TNF-induzierte Zytokinsekretion synovialer Fibroblasten von Patienten mit rheumatoider Arthritis oder Psoriasisarthritis
Creators: name: Frommer, Klaus
name: Rehart, Stefan
name: Müller-Ladner, Ulf
name: Neumann, Elena
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Rheumatoide Arthritis (RA) und Psoriasisarthritis (PsA) sind autoimmunbedingte Arthritiden mit zahlreichen Gemeinsamkeiten, aber auch Unterschieden. Secukinumab, ein Anti-IL 17-Biologikum, zeigt unter anderem eine bessere therapeutische Effektivität bei PsA-Patienten im Vergleich zu[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)