cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Arginase Inhibition Reverses Monocrotaline-Induced Pulmonary Hypertension
Creators: name: Jung, Christian
name: Grün, Katja
name: Betge, Stefan
name: Pernow, John
name: Kelm, Malte
name: Muessig, Johanna
name: Masyuk, Maryna
name: Kuethe, Friedhelm
name: Ndongson-Dongmo, Bernadin
name: Bauer, Reinhard
name: Lauten, Alexander
name: Schulze, P. Christian
name: Berndt, Alexander
name: Franz, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: pulmonary hypertension
subject: monocrotaline rat model
subject: arginase
subject: isoforms
subject: inhibition
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Pulmonary hypertension (PH) is a heterogeneous disorder associated with a poor prognosis. Thus, the development of novel treatment strategies is of great interest. The enzyme arginase (Arg) is emerging as important player in PH development. The aim of the current study was to determine the expression of ArgI and ArgII as well as the effects of Arg inhibition in a rat model of PH. PH was induced in 35 Sprague–Dawley rats by monocrotaline (MCT, 60 mg/kg as single-dose). There were three experimental groups: sham-treated controls (control group, n = 11), MCT-induced PH (MCT group, n = 11) and MCT-induced PH treated with the Arg inhibitor Nω-hydroxy-nor-l-arginine (nor-NOHA; MCT/NorNoha group, n = 13). ArgI and ArgII expression was determined by immunohistochemistry and Western blot. Right ventricular systolic pressure (RVPsys) was measured and lung tissue remodeling was determined. Induction of PH resulted in an increase in RVPsys (81 ± 16 mmHg) compared to the control group (41 ± 15 mmHg, p = 0.002) accompanied by a significant elevation of histological sum-score (8.2 ± 2.4 in the MCT compared to 1.6 ± 1.6 in the control group, p < 0.001). Both, ArgI and ArgII were relevantly expressed in lung tissue and there was a significant increase in the MCT compared to the control group (p < 0.01). Arg inhibition resulted in a significant reduction of RVPsys to 52 ± 19 mmHg (p = 0.006) and histological sum-score to 5.8 ± 1.4 compared to the MCT group (p = 0.022). PH leads to increased expression of Arg. Arg inhibition leads to reduction of RVPsys and diminished lung tissue remodeling and therefore represents a potential treatment strategy in PH.
title: Estadiaje local mediante RM de las neoformaciones rectales y correlación anátomo-radiológica.
Creators: name: Andrés Paz, Ana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Comparative studies
subject: MR
subject: Abdomen

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Revisar la utilidad de la RM en el estadiaje de las neoformaciones rectales. Evaluar la precisión del estadiaje local preoperatorio de las neoformaciones rectales mediante RM para la resección de los márgenes circunferenciales libres de...
DAVLAT BYUDJETI DAROMADLARINI OSHIRISH
Creators: name: Dusqulova, Amina
Publisher: name: Zenodo
Year: 2024

description: Ushbu tadqiqot davlat byudjeti daromadlarini oshirishning asosiy strategiyalarini o‘rganishga bag‘ishlangan. Tadqiqotda soliqlarni optimallashtirish, davlat xarajatlarini maqbullashtirish, iqtisodiy diversifikatsiya, texnologik innovatsiyalarni joriy etish va davlat moliyaviy boshqaruvini isloh qilish kabi chora-tadbirlarning byudjet barqarorligi va davlat daromadlariga ta’siri tahlil qilinadi. O‘zbekistonning so‘nggi yillardagi byudjet daromadlarini oshirish tajribasi, jumladan, yangi Soliq kodeksi va investitsion islohotlar natijalari o‘rganiladi. Tadqiqot natijalari davlat byudjeti barqarorligini ta’minlash uchun samarali strategiyalarni ishlab chiqishda qo‘llanilishi mumkin bo‘lgan tavsiyalarni taqdim etadi.
An explorative study on the use of coarse-grained protein models in structure-based virtual screening
Creators: name: Pui, Wee Yang
Publisher: name: Swinburne
Year: 2024

description: This research aimed to evaluate whether data from coarse-grained modeling could match explicit solvent molecular dynamics in virtual screening. By comparing protein models from both simulations using parameters such as receiver operating characteristic (ROC) curves and enrichment factor (EF), the study found that coarse-grained models shouldn't be dismissed in virtual screening. It suggests further research to clarify the role and potential of coarse-grained modeling in this field.
A typology for voice and music signals
Creators: name: Wu, Cheng
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Engineering, System Science.

description: With the high increase in the availability of digital music, it has become of interest to automatically query a database of musical pieces. At the same time, a feasible solution of this objective gives us an insight into how humans perceive and classify music. In this research, we discuss our approach to classify music into four categories: pop, classical, country and jazz. Songs are collected in wave format. We randomly chose five 10-second clips from different parts of a song. We discussed two families of features: wavelet features and time-based features. These features are capable of capturing the information of energy and time of voice signal. Instead of using traditional Mel-Frequency Cepstral Coefficients (MFCC)[7] methods, which are widely used in audio classification and music classification, we incorporate the features in statistical classification methods such as LDA, QDA and tree. Finally, we attempted to create an adaptive tree approach for classification. In this research, 130 songs are collected. Pop songs are collected in 4 languages, English, Chinese, Spanish and French. A cross validation method is used to compute the proportion of correctly classified songs. It is shown that the tree method has a proportion of correct classification equal 0.80 when pop and country are considered as one category.
Création théâtrale, inhumain et postmodernité.
Creators: name: Proulx, Isabelle.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Literature, Canadian (French).

description: La creation d'une piece de theatre sur l'amitie entre quatre etudiantes est le centre d'une reflexion sur l'inhumain dans l'art. Dans la piece, l'absence d'une des amies devient, pour les autres, l'occasion d'exprimer les reproches qu'elles entretiennent envers l'absente. Du babil, on passe rapidement a des paroles blessantes. Il s'ensuit une crucifixion verbale de l'absente. C'est le drame d'un discours banal qui s'avere porteur de mort. Cette creation est inseree dans la conception de l'inhumain elaboree par Jean-Francois Lyotard dans sa reflexion sur la postmodernite. Les ecrits de Theodor W. Adorno sont aussi examines pour etablir la valeur de l'art dans le contexte explicite ci-haut. Finalement, c'est au niveau du theatre de la cruaute d'Antonin Artaud que la problematique est reliee au theatre. Cette cruaute est l'une des manifestations de l'inhumain dans l'art.
The effects of di- and triacylglycerols on the charge, stability and conformation of HDL and on hepatic lipase activity.
Creators: name: Coffill, Cynthia Rose.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Chemistry, Biochemistry.

description: Alterations in HDL composition that occur in the hypertriglyceridemic state may modulate a number of events involved in cholesterol homeostasis. To elucidate the details of how HDL neutral acylated glycerol (NAG) composition can affect the molecular structure of HDL particles, the charge, conformation and stability of apoA-I have been investigated in homogeneous recombinant HDL particles (Lp2A-I) containing phosphatidylcholine (POPC), triolein (TG) and/or diolein (DG). The effect of HDL composition and structure on the hydrolysis of HDL phospholipids, DG and TG by hepatic lipase (HL) has also been investigated in native and Lp2A-I. In summary, DG causes specific conformational changes to apoA-I that give rise to a decrease in the particle surface potential and increase in stability. Together, these structural changes appear to regulate the actions of HL; HDL-DG content regulates the hydrolysis of phospholipid (PL), DG and TG by HL. The data indicates that hepatic lipase acts primarily as a surface lipid lipase with HDL particles and that DG is the preferred substrate of HL in HDL. (Abstract shortened by UMI.)
title: RM cardíaca para principiantes
Creators: name: Miralles Soria, Salvador
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Cardiac
subject: MR

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Hasta no hace mucho tiempo el corazón era el gran desconocido para la radiología torácica.
Con la aparición de la RM y los TC multidetector se consigue valorar el corazón tanto morfológica como funcionalmente. El objetivo de ésta...
Personality, Attentional Biases towards Emotional Faces and Symptoms of Mental Disorders in an Adolescent Sample
Creators: name: O’Leary-Barrett, Maeve
name: Pihl, Robert O.
name: Artiges, Eric
name: Banaschewski, Tobias
name: Bokde, Arun L. W.
name: Büchel, Christian
name: Flor, Herta
name: Frouin, Vincent
name: Garavan, Hugh
name: Heinz, Andreas
name: Ittermann, Bernd
name: Mann, Karl
name: Paillère-Martinot, Marie-Laure
name: Nees, Frauke
name: Paus, Tomas
name: Pausova, Zdenka
name: Poustka, Luise
name: Rietschel, Marcella
name: Robbins, Trevor W.
name: Smolka, Michael N.
name: Ströhle, Andreas
name: Schumann, Gunter
name: Conrod, Patricia J.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 100 Philosophie und Psychologie::150 Psychologie

description: Objective To investigate the role of personality factors and attentional biases towards emotional faces, in establishing concurrent and prospective risk for mental disorder diagnosis in adolescence. Method Data were obtained as part of the IMAGEN study, conducted across 8 European sites, with a community sample of 2257 adolescents. At 14 years, participants completed an emotional variant of the dot-probe task, as well two personality measures, namely the Substance Use Risk Profile Scale and the revised NEO Personality Inventory. At 14 and 16 years, participants and their parents were interviewed to determine symptoms of mental disorders. Results Personality traits were general and specific risk indicators for mental disorders at 14 years. Increased specificity was obtained when investigating the likelihood of mental disorders over a 2-year period, with the Substance Use Risk Profile Scale showing incremental validity over the NEO Personality Inventory. Attentional biases to emotional faces did not characterise or predict mental disorders examined in the current sample. Discussion Personality traits can indicate concurrent and prospective risk for mental disorders in a community youth sample, and identify at-risk youth beyond the impact of baseline symptoms. This study does not support the hypothesis that attentional biases mediate the relationship between personality and psychopathology in a community sample. Task and sample characteristics that contribute to differing results among studies are discussed.
Public engagement pathways for emerging GM insect technologies
Creators: name: Burgess, Michael M.
name: Mumford, John D.
name: Lavery, James V.
Publisher: name: BioMed Central
Year: 2018

description: Policy and management related to the release of organisms generated by emerging biotechnologies for pest management should be informed through public engagement. Regulatory decisions can be conceptually distinguished into the development of frameworks, the assessment of the release of a specific modified organism, and implementation decisions such as location and timing. Although these decisions are often intertwined in practice, the negotiation takes place at different stages of technology development and suggests different roles for public engagement. Some approaches to public engagement are more appropriate for different purposes and situations, and it is not always obvious how to go about matching the approach to the purpose. In addition to the diverse technologies involved in generating modified organisms, there are diverse publics with particular interests and different kinds of knowledge. Institutional interests range from commercial development to public regulation and future uptake. Contextual features, such as agency mandates, may limit or structure the extent and approach to public engagement. Different convening groups (government agencies, public interest groups, academics, businesses) and the kind of decision that is being considered determine what kind of input is needed and how the engaging groups will be constituted. This paper considers how the context of the release of genetically modified insects for pest control requires expanding approaches to the design of the public engagement.
title: CANCER DE PROSTATA: lo que el urólogo necesita saber.
Creators: name: González Humara, Beatriz
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Ultrasound
subject: CT
subject: MR
subject: Genital / Reproductive system male
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Conocer la información que los urólogos,
oncólogos y radioterapeutas demandan de las pruebas diagnósticas y que debemos incluir en los informes radiológicos de los pacientes con cáncer de...
title: Traumatismos en extremidades en la edad pediátrica
Creators: name: González Sánchez, Susana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Trauma
subject: Education
subject: Conventional radiography
subject: Paediatric

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo de este trabajo es describir y presentar diferentes tipos de fracturas propias de la edad infantil,
caracterizadas por una especial morfología debido a las peculiaridades del hueso de los...
Perceptions and Attitudes of Egyptian Health Professionals and Policy-Makers towards Pharmaceutical Sales Representatives and Other Promotional Activities
Creators: name: Kamal, Susan
name: Holmberg, Christine
name: Russell, Jean
name: Bochenek, Tomasz
name: Tobiasz-Adamczyk, Beata
name: Fischer, Christiane
name: Tinnemann, Peter
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Pharmaceutical promotion activities in low and middle-income countries are often neither regulated nor monitored. While Egypt has the highest population and per capita use of medicines in the Arab world, we know very little about pharmaceutical companies promotional activities in the country. Aim To explore and analyze the perceptions of physicians towards promotional and marketing activities of pharmaceutical companies among physicians and pharmacists in Egypt. Methodology Perspectives of different healthcare system stakeholders were explored through semi-structured, in-depth interviews conducted in 2014 in Cairo, Egypt. Interviewees were chosen via purposive sampling and snowball technique. Each interview was recorded and transcribed. Then qualitative, thematic analysis was conducted with the help of NVIVO software. Findings The majority of physicians and pharmacists acknowledged exposure to pharmaceutical promotion. It was commonly believed that interaction with the pharmaceutical industry is necessary and both associated risks and benefits were acknowledged. The interviewed physicians considered themselves competent enough to minimize risks and maximize benefits to their prescribing habits. Views diverged on the extent and magnitude of the risks and benefits of pharmaceutical promotion, especially in regard to the influence on patients’ health. Conclusions Pharmaceutical promotion in Egypt is intensely directed at prescribers and dispensers. Physicians, pharmacists and policymakers expressed little skepticism to the influence of promotion towards their individual prescribing. Raising awareness of the pitfalls of pharmaceutical promotion is necessary, especially among the less experienced physicians
LOTOS based conformance testing: The theory and a tool.
Creators: name: Jaouani, Rafik.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Computer Science.

description: Computers in a network have to obey to well-defined protocols in order to communicate properly. These protocols can be very complex and their implementation is often subject to errors. One question arises after implementing a communication protocol: does the implementation conform to its specification? The process of answering this question is called conformance testing. The introduction of formal description techniques, in particular LOTOS, made it possible to formalize the problem and to develop formal methods to check the conformance of implementations to their specifications. To test for conformance, tests can be derived from specifications and then applied to implementations. The CO-OP method is the basic test case generation method for LOTOS. It is used in order to generate canonical testers from specifications. The method that has been published in the literature can only deal with specifications that do not involve recursion (finite behaviours). We have generalized the CO-OP method in such a way as to remove this restriction: the only restriction we have is that the specification must have an expansion that can fit in memory. The generalized method also expands the original method to support a large subset of Full LOTOS behaviours. In most cases, testing does not prove conformance but attempts to reduce the errors in implementations. We have developed an algorithm for proving conformance in the special case of Basic LOTOS behaviours. All algorithms presented in the thesis were implemented in what we call the LOTEST tool.
title: Urinomas y fístulas urinarias: causas, características radiológicas y tratamiento.
Creators: name: González Humara, Beatriz
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Kidney
subject: CT
subject: Ultrasound
subject: Conventional radiography
subject: Fistula

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Presentar casos de urinomas y fístulas urinarias de riñon,
uréteres,
vejiga y uretra. Describir las características radiológicas de las extravasaciones de orina. Conocer las causas y las posibles complicaciones de la rotura de vía...
Modification of the surface of superparamagnetic iron oxide nanoparticles to enable their safe application in humans
Creators: name: Strehl, Cindy
name: Maurizi, Lionel
name: Gaber, Timo
name: Hoff, Paula
name: Broschard, Thomas
name: Poole, A. Robin
name: Hofmann, Heinrich
name: Buttgereit, Frank
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: iron oxide nanoparticles
subject: cytokine secretion
subject: cell viability
subject: polyvinyl alcohol
subject: cross-linking
subject: surface charge
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Abstract: Combined individually tailored methods for diagnosis and therapy (theragnostics) could be beneficial in destructive diseases, such as rheumatoid arthritis. Nanoparticles are promising candidates for theragnostics due to their excellent biocompatibility. Nanoparticle modifications, such as improved surface coating, are in development to meet various requirements, although safety concerns mean that modified nanoparticles require further review before their use in medical applications is permitted. We have previously demonstrated that iron oxide nanoparticles with amino-polyvinyl alcohol (a-PVA) adsorbed on their surfaces have the unwanted effect of increasing human immune cell cytokine secretion. We hypothesized that this immune response was caused by free-floating PVA. The aim of the present study was to prevent unwanted immune reactions by further surface modification of the a-PVA nanoparticles. After cross-linking of PVA to nanoparticles to produce PVA-grafted nanoparticles, and reduction of their zeta potential, the effects on cell viability and cytokine secretion were analyzed. PVA-grafted nanoparticles still stimulated elevated cytokine secretion from human immune cells; however, this was inhibited after reduction of the zeta potential. In conclusion, covalent cross-linking of PVA to nanoparticles and adjustment of the surface charge rendered them nontoxic to immune cells, nonimmunogenic, and potentially suitable for use as theragnostic agents.
Identifying the etiology and pathophysiology underlying stunting and environmental enteropathy: study protocol of the AFRIBIOTA project
Creators: name: Vonaesch, Pascale
name: Randremanana, Rindra
name: Gody, Jean-Chrysostome
name: Collard, Jean-Marc
name: Giles-Vernick, Tamara
name: Doria, Maria
name: Vigan-Womas, Inès
name: Rubbo, Pierre-Alain
name: Etienne, Aurélie
name: Andriatahirintsoa, Emilson J.
name: Kapel, Nathalie
name: Brown, Eric
name: Huus, Kelsey E.
name: Duffy, Darragh
name: Finlay, B. Brett, 1959-
name: Hasan, Milena
name: Hunald, Francis A.
name: Robinson, Annick
name: Manirakiza, Alexandre
name: Wegener-Parfrey, Laura
name: Vray, Muriel
name: Sansonetti, Philippe J.
Publisher: name: BioMed Central
Year: 2018

description: Background: Globally one out of four children under 5 years is affected by linear growth delay (stunting). This syndrome has severe long-term sequelae including increased risk of illness and mortality and delayed psychomotor development. Stunting is a syndrome that is linked to poor nutrition and repeated infections. To date, the treatment of stunted children is challenging as the underlying etiology and pathophysiological mechanisms remain elusive. We hypothesize that pediatric environmental enteropathy (PEE), a chronic inflammation of the small intestine, plays a major role in the pathophysiology of stunting, failure of nutritional interventions and diminished response to oral vaccines, potentially via changes in the composition of the pro- and eukaryotic intestinal communities. The main objective of AFRIBIOTA is to describe the intestinal dysbiosis observed in the context of stunting and to link it to PEE. Secondary objectives include the identification of the broader socio-economic environment and biological and environmental risk factors for stunting and PEE as well as the testing of a set of easy-to-use candidate biomarkers for PEE. We also assess host outcomes including mucosal and systemic immunity and psychomotor development. This article describes the rationale and study protocol of the AFRIBIOTA project. Methods: AFRIBIOTA is a case-control study for stunting recruiting children in Bangui, Central African Republic and in Antananarivo, Madagascar. In each country, 460 children aged 2–5 years with no overt signs of gastrointestinal disease are recruited (260 with no growth delay, 100 moderately stunted and 100 severely stunted). We compare the intestinal microbiota composition (gastric and small intestinal aspirates; feces), the mucosal and systemic immune status and the psychomotor development of children with stunting and/or PEE compared to non-stunted controls. We also perform anthropological and epidemiological investigations of the children’s broader living conditions and assess risk factors using a standardized questionnaire. Discussion: To date, the pathophysiology and risk factors of stunting and PEE have been insufficiently investigated. AFRIBIOTA will add new insights into the pathophysiology underlying stunting and PEE and in doing so will enable implementation of new biomarkers and design of evidence-based treatment strategies for these two syndromes.
Shocks and star formation in Stephan's Quintet. I. Gemini Spectroscopy of H?-bright Knots
Creators: name: Konstantopoulos, I. S.
name: Appleton, P. N.
name: Guillard, P.
name: Trancho, G.
name: Cluver, Michelle
name: Bastian, N.
name: Charlton, J. C.
name: Fedotov, K.
name: Gallagher, S. C.
name: Smith, L. J.
name: Struck, C. J.
Publisher: name: Swinburne
Year: 2024

description: We present a Gemini-GMOS spectroscopic study of Hubble Space Telescope (HST)-selected Hα-emitting regions in Stephan's Quintet (HCG 92), a nearby compact galaxy group, with the aim of disentangling the processes of shock-induced heating and star formation in its intra-group medium. The ≈40 sources are distributed across the system, but most densely concentrated in the ~kiloparsec-long shock region. Their spectra neatly divide them into narrow- and broad-line emitters, and we decompose the latter into three or more emission peaks corresponding to spatial elements discernible in HST imaging. The emission-line ratios of the two populations of Hα-emitters confirm their nature as H II regions (90% of the sample) or molecular gas heated by a shock front propagating at lsim300 km s-1. Their redshift distribution reveals interesting three-dimensional structure with respect to gas-phase baryons, with no H II regions associated with shocked gas, no shocked regions in the intruder galaxy NGC 7318B, and a sharp boundary between shocks and star formation. We conclude that star formation is inhibited substantially, if not entirely, in the shock region. Attributing those H II regions projected against the shock to the intruder, we find a lopsided distribution of star formation in this galaxy, reminiscent of pileup regions in models of interacting galaxies. The Hα luminosities imply mass outputs, star formation rates, and efficiencies similar to nearby star-forming regions. Two large knots are an exception to this, being comparable in stellar output to the prolific 30 Doradus region. We also examine Stephan's Quintet in the context of compact galaxy group evolution, as a paradigm for intermittent star formation histories in the presence of a rich, X-ray-emitting intra-group medium. All spectra are provided as supplemental materials.
Sechs Gesänge : für vierstimmigen Frauenchor und Soli : op. 45 : zum Gebrauch für Frauen Gesangvereine
Gesänge Frauenchor Frauensingstimme (1)
Creators: name: Möhring, Ferdinand
Publisher: name: Julius Friedlaender
Year: 1860

description: Heft 1 Hochzeit "Er liebt mich, er liebt mich nicht" [Text] v. Kletke Vogelsprache [Text:] Gruppe
description: Heft 2 Wandrers Nachtlied [Text:] Göthe Vergebung [Text:] Borowsky Lerche [Text:] G. Hohenhausen
description: componirt von F. Möhring
description: Auf dem Umschlag: Musiksammlung von F. Riggenbach-Stehlin
P-cycle in multi-layer and multi-failure network survivability
Creators: name: Wang, Hongxia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Engineering, Electronics and Electrical.

description: Network survivability is a fascinating topic, in both research area and our daily life. P-cycles have gradually become a promising solution for mesh reliable networks, summed up as "ring like speed with mesh like efficiency". In this thesis, we finely integrated p-cycle with multilayer technology and presented a new way for modern network: multilayer framework for p-cycle survivability. Based on this new framework, we also proposed a new mechanism which can survive multiple failures. This thesis aims to provide an efficient solution to adapt p-cycle to modern multilayer network architecture, and to survive multiple failures.
WP2A5: Резюме публікацій з відкритим доступом Локальний аналіз: Приклади ініціатив із залучення громадян в Україні, організованих балтійськими університетами
Creators: name: Pranckutė, Aistė
name: Abolina, Inese
name: Beitane, Anna
name: Berezko, Oleksandr
name: Boichenko, Kateryna
name: Gibson, Catherine Helen
name: Jõgi, Larissa
name: Oikonomou, Stefania
name: Pata, Kai
name: Shilinh, Anna
name: Stučka, Malvīne
name: Tautkevičienė, Gintarė
name: Teder, Lianne
name: Vali, Fidan
name: Vovk, Nataliia
name: Zourou, Katerina
Publisher: name: Zenodo
Year: 2023

description: DESCRIPTION: Synthesis of open access project publication "Landscape analysis: Examples of citizen engagement initiatives for Ukraine organized by Baltic Universities" shortly presents 6 case studies, including 5 world cafe discussions held on the premises of Baltics4UA partner universities and one webinar hosted by business partner Web2Learn. This is the version of synthesis in the Ukrainian language. 
This publication was produced as part of Work Package 2 of the EU-funded project Baltics4UA: "Supporting Ukraine through citizen engagement at Baltic Universities'' (https://baltics4ua.eu/, Project Number 2022-2-EE01-KA220-HED-000096422). 
This project has been funded with support from the European Commission. This deliverable reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.
title: Tau plasma levels in subjective cognitive decline
title: Results from the DELCODE study
titleType: Subtitle
Creators: name: Müller, Stephan
name: Preische, Oliver
name: Göpfert, Jens C.
name: Yanez, Viviana A. Carcamo
name: Joos, Thomas O.
name: Boecker, Henning
name: Priller, Josef
name: Peters, Oliver
name: Menne, Felix [U.A.]
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Alzheimer's disease
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Previous studies have demonstrated increased tau plasma levels in patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) due to AD. Much less is known whether increased tau plasma levels can already be detected in the pre-MCI stage of subjective cognitive decline (SCD). In the present study we measured tau plasma levels in 111 SCD patients and 134 age- and gender-matched cognitively healthy controls participating in the DZNE (German Center for Neurodegenerative Diseases) longitudinal study on cognition and dementia (DELCODE). Tau plasma levels were measured using ultra-sensitive, single-molecule array (Simoa) technology. We found no significant different tau plasma levels in SCD (3.4 pg/ml) compared with healthy controls (3.6 pg/ml) after controlling for age, gender, and education (p = 0.137). In addition, tau plasma levels did not correlate with Aβ42 (r = 0.073; p = 0.634), tau (r = −0.179; p = 0.240), and p-tau181 (r = −0.208; p = 0.171) cerebrospinal fluid (CSF) levels in a subgroup of 45 SCD patients with available CSF. In conclusion, plasma tau is not increased in SCD patients. In addition, the lack of correlation between tau in plasma and CSF in the examined cohort suggests that tau levels are affected by different factors in both biofluids.
Measuring consumer surplus for nonmonotonic changes in utility.
Creators: name: Rajan, Chitra.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Economics, General.

description: We are concerned here with the problem of measuring consumer surplus from ordinary demand functions, in those situations where changes in the budget lead to variations in utility that are not monotonic. We will show that many of the problems that arise for nonmonotonic paths either do not exist, or are insignificant when consumer surplus is measured for monotonic paths. The first problem considered is the integrability question: the conditions which guarantee that the demand functions can be integrated to yield the generating utility function. The problem of obtaining a valid surplus measure that is consistent with consumer preferences is considered. In most practical applications of welfare analysis, use is made of the Marshallian surplus, on the grounds that it varies only slightly along alternate paths, and along any particular path, will provide a good approximation to the Hicksian variations. While this is true for monotonic paths, we show that it is not so for paths that lead to nonmonotonic utility changes. Such approximations are not necessary, as the equivalent variation can be calculated directly from ordinary demand functions. When preferences are quasihomothetic, expansion paths are linear, which allows us to calculate the integrating factor, and hence the indirect utility function. In the more general case, compensated changes in income are considered for the budget path, which gives us the expenditure function corresponding to the final utility level. This approach involves solving a differential equation. Closed form solutions as well as the method of numerical integration are considered. As an example of paths that lead to nonmonotonic changes in utility, we consider the effects of a move to time differentiated electricity rates on the welfare of the consumer. (Abstract shortened by UMI.)
The geography of belonging: Place, proximity, and social support
Creators: name: Anderson, Dale E
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Geography.

description: This thesis is about belonging, about people's ties to others and the nature of those ties; such ties are referred to by social scientists as social support. Social support has traditionally been studied with respect to two dimensions: structural dimensions refer to the characteristics of the individuals who are part of an individual's social support network (such as their number, or the frequency with which they interact); functional dimensions refer to the types of support that are exchanged between people (such as practical help, or affection). In the early 1980s, Graham Rowles, an American geographer studying the elderly, proposed that the combination of the support received by the elderly, and the place in which it was provided, gave rise to sociospatial support---a concept that has lain dormant ever since. This thesis is an attempt to reinvestigate this concept, and explore how place (i.e., the neighbourhood) and proximity influence the social support that is received by the elderly (those aged 55 to 74) in the Outaouais region of the Province of Quebec. The research makes use of three data sources: information on basic structural and functional dimensions of support in the lives of the elderly is provided by the National Population Health Survey; a regional survey of the Outaouais elderly provides insights into the role of the neighbourhood and neighbours in the provision of support, with a particular interest in the provision of support by nonkin; and, finally, a series of interviews with selected elderly allow for understanding of the previous two stages within the context of individual experience. The research findings enabled the proposal of the kinship continuum, in which it was hypothesized that ties to nonkin could be placed along a continuum of intimacy or propinquity, with kindred of recognition anchoring one end, and kindred of communitatis securing the other. The most substantial contribution was the proposal of a framework for a geography of belonging, in which three modalities---network, properties of the person, and milieu---were identified and delineated along a number of attributes, in an attempt to advance Rowles's original concept.
Biogeochemical dynamics of iron and sulfur in sediments from hydro-electric dams submitted to wetting and drying cycles
Creators: name: Nugent, Michelle V
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Geology.
subject: Biogeochemistry.

description: Water level changes due to the decommissioning of hydro-electric dams can result in sediment exposure to air. Oxidation of sediments can decrease the pH as a result of iron sulfides changing into iron oxides. The present study was designed to simulate drying and wetting cycles of shallow lake sediments from two lakes (Stump and Black Donald Lakes in Ontario), in order to assess the mineralogical changes of Fe-rich minerals. Our results indicate that the total reactive iron fraction of the sediment increased after the wetting and drying cycles. This increase was caused by the weathering of pyrite and Fe-silicates and their subsequent transformation into more Fe-reactive mineral species. The pH of the surface sediments also decreased following the addition of simulated rainwater and the oxidation of iron sulfides in the sediments. This preliminary study shows that the decommissioning of hydro-electric dams will have an effect on the biogeochemical cycles of iron and sulfur.
The CANadian Pediatric Weight management Registry (CANPWR): lessons learned from developing and initiating a national, multi-centre study embedded in pediatric clinical practice
Creators: name: Morrison, Katherine M
name: Ball, Geoff D C
name: Ho, Josephine
name: Mackie, Pam
name: Buchholz, Annick
name: Chanoine, Jean-Pierre
name: Hamilton, Jill
name: Laberge, Anne-Marie
name: Legault, Laurent
name: Thabane, Lehana
name: Tremblay, Mark
name: Zenlea, Ian
Publisher: name: BioMed Central
Year: 2018

description: Background: There is increasing recognition of the value of “real-world evidence” in evaluating health care services. Registry-based, observational studies conducted in clinical settings represent a relevant model to achieve this directive. Starting in 2010, we undertook a longitudinal, observational study (the CANadian Pediatric Weight management Registry [CANPWR]), which is embedded in 10 multidisciplinary, pediatric weight management clinics across Canada. The objective of this paper was to share the lessons our team learned from this multi-centre project. Methods: Data sources included a retrospective review of minutes from 120 teleconferences with research staff and investigators, notes taken during clinical site visits made by project leaders, information from quality control processes to ensure data accuracy and completeness, and a study-specific survey that was sent to all sites to solicit feedback from research team members (n = 9). Through an iterative process, the writing group identified key themes that surfaced during review of these information sources and final lessons learned were developed. Results: Several key lessons emerged from our research, including the (1) value of pilot studies and central research coordination, (2) need for effective and regular communication, (3) importance of consensus on determining outcome measures, (4) challenge of embedding research within clinical practice, and (5) difficulty in recruiting and retaining participants. The sites were, in spite of these challenges, enthusiastic about the benefits of participating in multi-centre collaborative studies. Conclusion: Despite some challenges, multi-centre observational studies embedded in pediatric weight management clinics are feasible and can contribute important, practical insights into the effectiveness of health services for managing pediatric obesity in real-world settings.
title: Does an Immigrant Background Affect the Indication, Incidence or Outcome of Emergency Cesarean Section?
title: Results of the Prospective Data Collection of 111 Births
titleType: Subtitle
Creators: name: David, Matthias
name: Scherer, Katrin Alexandra
name: Henrich, Wolfgang
name: Breckenkamp, Jürgen
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: cesarean section
subject: emergency cesarean section
subject: immigrant women
subject: perinatal outcome
subject: Sectio caesarea
subject: Notsectio
subject: Migrantinnen
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::613 Persönliche Gesundheit und Sicherheit

description: Objectives: Does the incidence and/or indication(s) for emergency cesarean section differ if the pregnant woman has an immigrant background (IB)? Does a lack of language proficiency (communication problems) and a low acculturation level result in a longer decision-to-delivery interval (D-D interval)? Are neonates born to women with IB by emergency cesarean section in a poorer condition post delivery? Patient cohorts and method: Standardized interviews were carried out before or immediately after delivery in three Berlin obstetric hospitals. Questions were asked about the sociodemographic background and care aspects as well as about immigration and level of acculturation. Collected data were linked to information obtained from the expectant motherʼs antenatal records and to care data and perinatal data routinely recorded by the hospitals. Data was analyzed using regression models which adjusted for age, parity, and socio-economic status. Results: The total patient population consisted of 7100 women (rate of response: 89.6%); of these women, 111 required emergency cesarean section (50 women without IB, 61 immigrant women). Risk factors such as late first antenatal check-up, gestational diabetes, pregnancy-induced hypertension, fetal macrosomia, smoking, and weight gain were similar in both patient cohorts. The incidence of and indications for emergency cesarean section and the D-D interval were similar for both groups. Limited German language proficiency and low levels of acculturation among immigrant women did not prolong the D-D interval. There were no statistically relevant differences between immigrant and non-immigrant cohorts with regard to adverse neonatal conditions (5-minute Apgar score ≤ 7, umbilical cord arterial pH
The Role of Artificial Intelligence for Business Value: A Hong Kong Case Study
Creators: name: Lee, Chi Man
Publisher: name: Swinburne
Year: 2024

description: This study explores how artificial intelligence (AI) contributes to business value, through a case study of Hong Kong organizations. It presents a model illustrating how AI creates business value through the development of process-oriented dynamic capabilities and highlights the role of AI orientation, an organization's commitment to AI research and development, as well as the acquisition and application of AI, in the investment in AI assets and the development of AI capabilities. The research addresses a gap in understanding the impact of AI on business value and offers a framework that assists practitioners in leveraging AI resources and capabilities.
Role of extracellular peroxidase in maize, Zea mays (L.) resistance to the European corn borer, Ostrinia nubilalis (Huebner).
Creators: name: MacIsaac, Susan Marie.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Biology, Botany.

description: A cell wall peroxidase (E.C. 1.11.17) mediates the formation of diferulic acid, (E,E)-$4,4\sp\prime$-dihydroxy-$5,5\sp\prime$-dimethoxy-$3\sp\prime$-bicinnamic acid, through the cross-linking of hemicellulose bound ferulic acid, 3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid, which increases the mechanical strength of the cell wall and its resistance to insects. It was hypothesized that the level of the cell wall bound peroxidase activity was positively correlated across genotypes with the concentration of cell wall bound diferulic acid concentration and resistance to the European corn borer (ECB), Ostrinia nubilalis Hubner, in field grown maize, Zea mays (L.). Activity of the peroxidase was highest at the base of the whorl leaf and rapidly declined with tissue age. Among genotypes, the activity varied widely with no apparent relationship with either ferulic acid, diferulic acid or consumption rate. These results suggest that while diferulic acid may be an indicator of resistance, cell wall bound peroxidase does not play a regulatory role in its formation. (Abstract shortened by UMI.)
title: Gas ectópico abdominopélvico en adultos: perlas y errores diagnósticos
Creators: name: Pulido Rozo, M. Claudia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: CT
subject: Outcomes analysis

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo de este trabajo es diferenciar las causas patológicas de las no patológicas en los casos que presentan gas ectópico en el abdomen y la pelvis con el fin de optimizar una conducta terapéutica adecuada para cada caso,
sea si implica...
L'érotisme au féminin selon Anne Dandurand et Alina Reyes.
Creators: name: Lévesque, Mylène.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Literature, Modern.

description: L'institution qui a pendant longtemps occultee la litterature erotique manifeste aujourd'hui un interet nouveau pour ce champ litteraire. Or, avec la prise de parole des femmes, la litterature erotique est devenue accessible non seulement a l'ecriture au feminin mais aussi a la diffusion des textes erotiques ecrits par des femmes. Notre these s'interesse a la specificite de l'erotisme au feminin dans des textes contemporains ecrits par des femmes. La premiere auteure, Anne Dandurand, est reconnue comme une des pionnieres (sic) quebecoises en litterature erotique au feminin. Quant a la seconde, Alina Reyes, elle acceda a la renommee avec son petit roman Le Boucher. Toutes deux osent affirmer un erotisme qui se hisse hors des spheres de la litterature erotique classique a savoir celle ecrite par et pour les hommes. Aussi, nous etudierons de quelles facons cette nouvelle ecriture reprend ou refuse les stereotypes vehicules depuis toujours dans la litterature erotique au masculin.
title: Optimierung der herzchirurgischen Forschung und Versorgung durch intelligente Automatisierung der Datenprozessierung
title: von reproduzierbarer Forschung bis zur künstlichen Intelligenz
titleType: Subtitle
Creators: name: Meyer, Alexander
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2020
Subjects: subject: Machine Learning
subject: Heart Surgery
subject: reproducible research
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Die vorgestellten Arbeiten nutzen alle Möglichkeiten der fortgeschrittenen Datenverarbeitung und des “reproducible research” Ansatzes wie in der Einleitung der Arbeit beschrieben. Die erste Arbeit (siehe Publikation 1), eine tierexperimentelle Arbeit aus der biomedizinischen Grundlagenwissenschaft, nutzt hierarchische Modellierung und einen formalisierten Analyseansatz. Die folgenden drei Arbeiten kommen aus dem Bereich der klinischen Forschung; hier wurde eine umfassende Programmbibliothek entwickelt, mit deren Hilfe agile und dennoch wissenschaftlich höchsten Ansprüchen genügende Analysen retro- und auch prospektiver Kohorten semi-automatisch ermöglicht werden. Alle Tabellen, Grafiken und analytischen Ergebnisse aus den Publikationen stammen direkt aus der Verwendung der entwickelten Programmbibliothek. In Publikation 5 wird ein Ansatz der Echtzeit-Qualitätskontrolle für chirurgische Eingriffe vorgestellt. Ein Aufbau eines solchen Systems ermöglicht die Nutzung von Big Data Methoden und die Verwendung der von uns publizierten Open Source Programmbibliothek rcusum (siehe Publikation 5). Die letzte Arbeit beschreibt die Entwicklung und Validierung einer Big Data und KI Plattform zur Echtzeit Prädiktion von chirurgischen Komplikationen in der postoperativen Phase auf der Intensivstation (Publikation 6). Zusammenfassend erlaubt die Nutzung der in dieser kumulativen Arbeit genutzten Methoden der Datenverarbeitung und -analytik sowohl die Erstellung robuster und schneller Forschungsarbeiten als auch die Entwicklung innovativer Risikostratifizierungs-Werkzeuge. Beides kommt konkret mittel- und unmittelbar den Patienten und dem medizinischen Fortschritt im Allgemeinen zugute.
title: Manifestaciones Radiológicas de la Neumonía en la práctica diaria. Sujeto sano inmunocompetente.
Creators: name: Aguilar García, Jesús José
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Thorax
subject: Education

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
La Radiografía Simple de Tórax (RST) es la prueba ‘gold standard’ para el diagnóstico de la neumonía.
En esta comunicación pretendemos revisar los hallazgos radiológicos detectados en la RST,
de sujetos previamente sanos afectos de...