cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SARS-CoV-2 Mitigation Strategies, Testing, and Cases at 254 Jails in the US Southeast, October 2020 to May 2021
Creators: name: DiRosa, E.
name: Powers, K.A.
name: Blue, C.
name: Levintow, S.N.
name: Rosen, D.L.
name: Brown, M.E.
name: Bradley-Bull, S.
name: Carda-Auten, J.
Publisher: name: American Public Health Association Inc.
Year: 2022

description: Objectives. To characterize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mitigation strategies, testing, and cases across county jails in the Southeastern United States, examining variability by jail characteristics. Methods. We administered a 1-time telephone survey to personnel of 254 jails in Alabama, Georgia, North Carolina, and South Carolina between October 2020 and May 2021. Results. Some SARS-CoV-2 mitigation strategies (e.g., screening at intake, isolation and masking for symptomatic persons) were commonly reported (≥ 75% of jails). Other measures, such as masking regardless of symptoms (52%) and screening at release (26%), were less common and varied by jail state or population size. Overall, 41% of jails reported no SARS-CoV-2 testing in the past 30 days. Jails with testing (59%) tested a median of 6 per 100 incarcerated persons; of those jails, one third reported 1 or more cases of positive tests. Although most jails detected no cases, in the 20% of all jails with 1 or more case in the past 30 days, 1 in 5 tests was positive. Conclusions. There was low testing coverage and variable implementation of SARS-CoV-2 mitigation strategies in Southeastern US jails during the first year of the COVID-19 pandemic.
Fractional Topological Insulators: from sliding Luttinger Liquids to Chern-Simons theory
Creators: name: Santos, Raul A.
name: Huang, Chia-Wei
name: Gefen, Yuval
name: Gutman, D. B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The sliding Luttinger liquids (LL) approach is applied to study fractional topological insulators (FTI). We show that FTI is the low energy fixed point of the theory for realistic spin-orbit and electron-electron interaction. We find that the topological phase pertains in the presence of interaction that breaks the spin invariance and its boundaries are even extended by those terms. Finally we show that one dimensional chiral anomaly in the LL leads to the emergence of topological Chern-Simons terms in the effective gauge theory of the FTI state.
description: 15 pages, 6 figures. Changes in style. Supplementary material expanded. Added references
Avalanches, loading and finite size effects in 2D amorphous plasticity: results from a finite element model
Creators: name: Sandfeld, Stefan
name: Budrikis, Zoe
name: Zapperi, Stefano
name: Castellanos, David Fernandez
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Crystalline plasticity is strongly interlinked with dislocation mechanics and nowadays is relatively well understood. Concepts and physical models of plastic deformation in amorphous materials on the other hand - where the concept of linear lattice defects is not applicable - still are lagging behind. We introduce an eigenstrain-based finite element lattice model for simulations of shear band formation and strain avalanches. Our model allows us to study the influence of surfaces and finite size effects on the statistics of avalanches. We find that even with relatively complex loading conditions and open boundary conditions, critical exponents describing avalanche statistics are unchanged, which validates the use of simpler scalar lattice-based models to study these phenomena.
description: Journal of Statistical Mechanics: Theory and Experiment, 2015, P02011
Additional file 1 of Outcomes of mitochondrial long chain fatty acid oxidation and carnitine defects from a single center metabolic genetics clinic
Creators: name: Ambrose, Anastasia
name: Sheehan, Melissa
name: Bahl, Shalini
name: Athey, Taryn
name: Ghai-Jain, Shailly
name: Chan, Alicia
name: Mercimek-Andrews, Saadet
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 60506 Virology

description: Additional file 1. Table S1: Newborn screening results are summarized in Table S1. Table S2. All variants and their ACMG classification are summarized in Table S2. Table S3: Biochemical features, illness management, and number of lifetime hospital admissions are summarized in Table S3.
Additional file 1: of Impact of cowâ  s milk intake on exercise performance and recovery of muscle function: a systematic review
Creators: name: Alcantara, Juan
name: Sanchez-Delgado, Guillermo
name: Martinez-Tellez, Borja
name: Labayen, Idoia
name: Jonatan Ruiz
Publisher: name: Figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Table S1. Search equations for both databases. (DOCX 14 kb)
Should Government Play a Strict or Lenient Role? An Evolutionary Game Analysis of Implementing the Forest Ecological Bank Policy
Creators: name: Nie, Xin
name: Li, Weijuan
name: Yang, Mengshi
name: Wang, Han
name: Zang, Ran
name: Chen, Zhoupeng
Publisher: name: MDPI
Year: 2023

description: As one of the specific practices of natural resource index trading, the forest ecological bank policy (FEB) is essentially a market-based tool. With the deepening of ecological governance, the FEB policy has also become the main method chosen to solve the economic development problems in ecologically rich “low-lying” areas. However, in the process of implementing the FEB policy, the differences in the demands of various stakeholders were found to have led to a complex game phenomenon, resulting in deviations in policy implementation. This study constructs a multiplayer evolutionary game model between local governments and enterprises of different scales and analyzes the evolutionary stabilization strategy (ESS) in the implementation of the FEB policy. The results show that, under different conditions, there are three stabilization strategies in the evolutionary game system, these correspond to F1 (0, 0, 0), F4 (0, 1, 1), and F5 (1, 0, 0), respectively, the implications are that the strict government role with an active regulatory strategy leads to companies of different sizes refusing to participate (i.e., F5) and the lax government role with a negative regulatory strategy leads to companies of different sizes refusing to participate (i.e., F1) or choosing to participate (i.e., F4). Among them, the strict government role stimulates the companies to participate in the FEB policy through the high intensity of government regulation. In addition, as the policy continues to be implemented, the influence of the strict regulation on the “participation” behavior of the companies decreases. Conversely, the lax government role allows the companies to give full play to their autonomy and obtain higher ecological and environmental benefits.
Vernunft, Freiheit und das Reich Gottes
Creators: name: Zaborowski, Holger
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 36 Nr. 1 (2007): Internationale katholische Zeitschrift Communio, Band 36, Heft 1
Liturgie als Epiphanie des Gottesreiches bei Alexander Schmemann
Creators: name: Slesinski, Robert
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 36 Nr. 1 (2007): Internationale katholische Zeitschrift Communio, Band 36, Heft 1
"Jesus verkündigte das Reich, und gekommen ist die Kirche"
Creators: name: Figura, Michael
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 36 Nr. 1 (2007): Internationale katholische Zeitschrift Communio, Band 36, Heft 1
Sinonasal complications of severe acute respiratory syndrome coronavirus-2: A single center case series
Creators: name: Chaskes M.
name: Lee S.E.
name: Quinsey C.S.
name: Thorp B.D.
name: Ghodke A.N.
name: Ebert C.S., Jr.
name: Senior B.A.
name: Stepp W.H.
name: Kimple A.J.
name: Kong K.A.
Publisher: name: John Wiley and Sons Inc
Year: 2023

description: Background: The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted in an unprecedented global pandemic. Most infected patients are either asymptomatic or have mild upper respiratory infection symptoms. However, life-threatening sequelae have been observed. In this report, we reviewed nine cases of patients with severe complications from sinonasal disease in the setting of acute SARS-CoV-2 infection. Methods: IRB approval was obtained prior to study initiation. A retrospective chart review was performed of patients admitted to a tertiary hospital with complex sinonasal symptoms that required otolaryngologic evaluation and management in the setting of concomitant SARS-CoV-2 infection. Results: Nine patients, ranging from ages 3 to 71 years, with sinonasal disease and simultaneous SARS-CoV-2 infection were identified. Initial presentations ranged from asymptomatic infection to mild/moderate disease (nasal obstruction, cough) or more severe sequelae including epistaxis, proptosis, or neurologic changes. SARS-CoV-2 tests were positive from one to 12 days after symptom onset, with three patients receiving SARS-CoV-2-directed treatment. Complex disease presentations included bilateral orbital abscesses, suppurative intracranial infection, cavernous sinus thrombosis with epidural abscess, systemic hematogenous spread with abscess development in four distinct anatomic locations, and hemorrhagic benign adenoidal tissue. Eight of nine patients (88.8%) required operative intervention. Patients with abscesses also required prolonged, culture-directed antibiotic courses. Conclusion: Though most SARS-CoV-2 infections are asymptomatic and/or self-limited, there is significant morbidity and mortality in patients with severe disease sequela as outlined in our reported cases. This suggests early identification and treatment of sinonasal disease in this patient population is critical to minimizing poor outcomes. Further research on the pathophysiology of these atypical presentations is needed. Level of Evidence: 4 (Case Series).
Simultaneous Acceleration of Protons and Electrons at Nonrelativistic Quasiparallel Collisionless Shocks
Creators: name: Park, Jaehong
name: Caprioli, Damiano
name: Spitkovsky, Anatoly
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Plasma Physics (physics.plasm-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: We study diffusive shock acceleration (DSA) of protons and electrons at nonrelativistic, high Mach number, quasiparallel, collisionless shocks by means of self-consistent 1D particle-in-cell simulations. For the first time, both species are found to develop power-law distributions with the universal spectral index $-4$ in momentum space, in agreement with the prediction of DSA. We find that scattering of both protons and electrons is mediated by right-handed circularly polarized waves excited by the current of energetic protons via non-resonant hybrid (Bell) instability. Protons are injected into DSA after a few gyro-cycles of shock drift acceleration (SDA), while electrons are first pre-heated via SDA, then energized via a hybrid acceleration process that involves both SDA and Fermi-like acceleration mediated by Bell waves, before eventual injection into DSA. Using the simulations we can measure the electron/proton ratio in accelerated particles, which is of paramount importance for explaining the cosmic ray fluxes measured at Earth and the multi-wavelength emission of astrophysical objects such as supernova remnants, radio supernovae, and galaxy clusters. We find the normalization of electron power-law is $\lesssim 10^{-2}$ that of the protons for strong nonrelativistic shocks.
description: 5 pages, 4 figures, accepted to PRL (some updates)
Spatiotemporal Evolution of Urban Agglomeration and Its Impact on Landscape Patterns in the Pearl River Delta, China
Creators: name: Meng, Chen
name: Xiao, Huirong
name: Haase, Dagmar
name: Liu, Yuhan
name: Ouyang, Linke
name: Zhuang, Minghao
name: Zhang, Qi
name: Wu, Hui
name: Wu, Caiyan
name: Wu, Jiong
name: Song, Conghe
name: Li, Junxiang
Publisher: name: MDPI
Year: 2023

description: An urban agglomeration is the engine of regional and national economic growth, but also causes many ecological and environmental issues that emerge from massive land changes. In this study, the spatiotemporal evolution of an urban agglomeration was quantified and its impacts on the urban and regional landscape patterns were evaluated. It showed that the urbanized land area of the Pearl River Delta Urban Agglomeration (PRDUA) in China nearly quadrupled, having linearly increased from 1819.8 km2 to 7092.2 km2 between 1985 and 2015. The average annual growth rate presented a bimodal wave-like pattern through time, indicating that the PRDUA has witnessed two rounds of the urbanization process. The growth modes (e.g., leapfrog, edge-expansion, infilling) were detected and they exhibited co-existing but alternating dominating patterns during urbanization, demonstrating that the spatiotemporal evolution of the urban development of the PRDUA follows the “spiral diffusion-coalescence” hypothesis. The morphology of the PRDUA presented an alternating dispersal-compact pattern over time. The city-level and regional-level landscape patterns changed synchronously with the spatiotemporal evolution of the PRDUA over time. The urbanization of the PRDUA increased both the complexity and aggregation of the landscape, but also resulted in an increasing fragmentation and decreasing connectivity of the natural landscape in the Pearl River Delta region. These findings are helpful for better understanding how urban agglomerations evolve and in providing insights for regional urban planning and sustainable land management.
Quantum teleportation between moving detectors
Creators: name: Lin, Shih-Yuin
name: Chou, Chung-Hsien
name: Hu, B. L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is commonly believed that the fidelity of quantum teleportation using localized quantum objects with one party or both accelerated in vacuum would be degraded due to the heat-up by the Unruh effect. In this paper we point out that the Unruh effect is not the whole story in accounting for all the relativistic effects in quantum teleportation. First, there could be degradation of fidelity by a common field environment even when both quantum objects are in inertial motion. Second, relativistic effects entering the description of the dynamics such as frame dependence, time dilation, and Doppler shift, already existent in inertial motion, can compete with or even overwhelm the effect due to uniform acceleration in a quantum field. We show it is not true that larger acceleration of an object would necessarily lead to a faster degradation of fidelity. These claims are based on four cases of quantum teleportation we studied using two Unruh-DeWitt detectors coupled via a common quantum field initially in the Minkowski vacuum. We find the quantum entanglement evaluated around the light cone, rather than the conventional ones evaluated on the Minkowski time-slices, is the necessary condition for the averaged fidelity of quantum teleportation beating the classical one. These results are useful as a guide to making judicious choices of states and parameter ranges and estimation of the efficiency of quantum teleportation in relativistic quantum systems under environmental influences.
description: 25 pages, 11 figures. Partly based on arXiv:1204.1525
Long-range spin imbalance in mesoscopic superconductors under a Zeeman splitting
Creators: name: Bobkova, I. V.
name: Bobkov, A. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We develop a theory of spin relaxation in Zeeman-splitted superconducting films at low temperatures. A new mechanism of spin relaxation, specific only for Zeeman-splitted superconductors is proposed. It can explain the extremely high spin relaxation lengths, experimentally observed in Zeeman-splitted superconductors, and their strong growth with the magnetic field. In the framework of this mechanism the observed spin signal is formed by the spin-independent nonequilibrium quasiparticle distribution weighted by the spin-split DOS. We demonstrate that the relaxation length of such a spin signal is determined by the energy relaxation length at energies of the order of the superconducting gap.
description: 6 pages, 2 figures, new references are added
SUSY Implications from WIMP Annihilation into Scalars at the Galactic Centre
Creators: name: Gherghetta, Tony
name: von Harling, Benedict
name: Medina, Anibal D.
name: Schmidt, Michael A.
name: Trott, Timothy
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: An excess in gamma-rays emanating from the galactic centre has recently been observed in the Fermi-LAT data. This signal can be interpreted as resulting from WIMP annihilation, with the spectrum well-fit by dark matter annihilating dominantly into either bottom-quark or Higgs pairs. Supersymmetric models provide a well-motivated framework to study the implications of this signal in these channels. With a neutralino dark matter candidate, the gamma-ray excess cannot be easily accommodated in the minimal supersymmetric model, which in any case requires tuning below the percent level to explain the observed Higgs mass. Instead we are naturally led to consider the next-to-minimal model with a singlet superfield. This not only allows for the annihilation channel into bottom-quark pairs to be implemented, but also provides new possibilities for annihilation into Higgs-pseudoscalar pairs. We show that the fit to the gamma-ray excess for the Higgs-pseudoscalar channel can be just as good as for annihilation into bottom-quark pairs. Moreover, in the parameter range of interest, the next-to-minimal supersymmetric model solves the mu-problem and can explain the 125 GeV Higgs mass with improved naturalness. We also consider an extension by adding a right-handed neutrino superfield with the right-handed sneutrino acting as a dark matter candidate. Interestingly, this allows for the annihilation into pseudoscalar pairs which also provide a good fit to the gamma-ray excess. Furthermore, in the case of a neutralino LSP, the late decay of a sneutrino NLSP can non-thermally produce the observed relic abundance. Finally, the WIMP annihilation into scalar pairs allows for the possibility of detecting the Higgs or pseudoscalar decay into two photons, providing a smoking-gun signal of the model.
description: 45 pages, 18 figures, 5 tables; v2: references added, version published in PRD
Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19
Creators: name: Aurora, H.
name: Cho, J.M.
name: Stewart, I.
name: Park, Y.
name: Tiruthani, K.
name: Lai, S.K.
name: Kumar, P.
name: Hutchins, J.
name: McSweeney, M.D.
name: Kim, C.
name: Schaefer, A.
name: Hickey, A.J.
name: Kang, H.
name: Lee, S.Y.
name: Richardson, Z.
name: Wolf, W.
Publisher: name: John Wiley and Sons Inc
Year: 2023

description: The respiratory tract represents the key target for antiviral delivery in early interventions to prevent severe COVID-19. While neutralizing monoclonal antibodies (mAb) possess considerable efficacy, their current reliance on parenteral dosing necessitates very large doses and places a substantial burden on the healthcare system. In contrast, direct inhaled delivery of mAb therapeutics offers the convenience of self-dosing at home, as well as much more efficient mAb delivery to the respiratory tract. Here, building on our previous discovery of Fc-mucin interactions crosslinking viruses to mucins, we showed that regdanvimab, a potent neutralizing mAb already approved for COVID-19 in several countries, can effectively trap SARS-CoV-2 virus-like particles in fresh human airway mucus. IN-006, a reformulation of regdanvimab, was stably nebulized across a wide range of concentrations, with no loss of activity and no formation of aggregates. Finally, nebulized delivery of IN-006 resulted in 100-fold greater mAb levels in the lungs of rats compared to serum, in marked contrast to intravenously dosed mAbs. These results not only support our current efforts to evaluate the safety and efficacy of IN-006 in clinical trials, but more broadly substantiate nebulized delivery of human antiviral mAbs as a new paradigm in treating SARS-CoV-2 and other respiratory pathologies.
Suicides in state prisons in the United States: Highlighting gaps in data
Creators: name: Behne, Michael F.
name: Lao, Jennifer
name: Brinkley-Rubinstein, Lauren
name: Peterson, Meghan
name: LeMasters, Katherine
Publisher: name: Public Library of Science
Year: 2023

description: Objectives Our objectives were to document data availability and reporting on suicide mortality in state prison systems. The United States leads the world in mass incarceration, a structural determinant of health, but lacks real-time reporting of prison health statistics. This absence is particularly notable in suicides, a leading cause of death that carceral policies play a key role in mitigating. Methods Suicide data for each state prison system from 2017–2021 were gathered through statistical reports, press releases, and Freedom of Information Act requests. We graded states based on data availability. Results Only sixteen states provide updated, frequent, granular, freely provided suicide data. An additional thirteen states provided frequently updated data but that had little granularity, was incomplete, or was not freely provided. Eight states provided sparse, infrequent, or outdated data, and thirteen provided no data at all. Conclusions The 2000 Death in Custody Reporting Act requires that states provide these data freely, yet the majority of states do not. There is a need for reliable, real-time data on suicides, suicide attempts, and conditions of confinement to better understand the harms of the carceral system and to advocate for change.
Integrability criterion in terms of coprime property for the discrete Toda equation
Creators: name: Kanki, Masataka
name: Mada, Jun
name: Tokihiro, Tetsuji
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mathematical Physics (math-ph)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences
subject: 37K10, 35A20, 47A07

description: We reformulate the singularity confinement of the discrete Toda equation. We prove the co-primeness property, which has been introduced in our previous paper (arXiv:1311.0060) as one of the integrability criteria, for the discrete Toda equation. We study three types of boundary conditions (semi-infinite, molecule, periodic) for the discrete Toda equation, and prove that the same co-primeness property holds for all the types of boundaries. (v2: typos corrected, final version to appear in J. Math. Phys.)
description: 31 pages, 4 figures
Support for regulation versus compliance: Face masks during COVID-19
Creators: name: Whittington, D.
name: Hanemann, M.
name: Carson, R.T.
name: Kim, D.
Publisher: name: Elsevier B.V.
Year: 2023

description: Objectives: Wearing masks could still be one of the few non-pharmaceutical interventions for controlling the pandemic. There are people who wear them and people who don't, but this framing is overly simplistic. We aim to chart the contradictions in attitudes and behavior regarding mask wearing and describe the messaging challenge that these generate. Study design: Our data come from a survey administered to a nationally representative sample of 2000 respondents from the YouGov panel of US households in August–September 2020. Methods: Respondents were asked whether they wear a facemask when they go outside their home since the COVID-19 epidemic began and whether they support or oppose your municipal government passing mask wearing regulation. We also collected respondents’ demographic and economic characteristics, knowledge regarding the facts of COVID-19 and political ideology. Results: A substantial majority of Americans (60%) both favor a masking requirement and are themselves wearing masks, while 13% oppose a mask mandate and do not wear masks. In contrast, 17% of Americans oppose a mask mandate but are currently wearing one, while 10% do not wear a mask but favor a mask mandate. These two groups are distinctively different from one another and the other groups in their socioeconomic characteristics, risk perception and political beliefs. Conclusions: Our study offers a better understanding of the mismatch between mask wearing behavior and attitude toward the mask mandate, which will help the public health authorities to devise policies regarding mask wearing as an effective intervention to manage the pandemic.
Hubble Space Telescope Observations of Sub-Damped Lyman-alpha Absorbers at z < 0.5, and Implications for Galaxy Chemical Evolution
Creators: name: Som, Debopam
name: Kulkarni, Varsha P.
name: Meiring, Joseph
name: York, Donald G.
name: Péroux, Celine
name: Lauroesch, James T.
name: Aller, Monique C.
name: Khare, Pushpa
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report observations of four sub-damped Lyman-alpha (sub-DLA) quasar absorbers at z<0.5 obtained with the Hubble Space Telescope Cosmic Origins Spectrograph. We measure the available neutrals or ions of C, N, O, Si, P, S, Ar, Mn, Fe, and/or Ni. Our data have doubled the sub-DLA metallicity samples at z<0.5 and improved constraints on sub-DLA chemical evolution. All four of our sub-DLAs are consistent with near-solar or super-solar metallicities and relatively modest ionization corrections; observations of more lines and detailed modeling will help to verify this. Combining our data with measurements from the literature, we confirm previous suggestions that the N(HI)-weighted mean metallicity of sub-DLAs exceeds that of DLAs at all redshifts studied, even after making ionization corrections for sub-DLAs. The absorber toward PHL 1598 shows significant dust depletion. The absorbers toward PHL 1226 and PKS 0439-433 show the S/P ratio consistent with solar, i.e., they lack a profound odd-even effect. The absorber toward Q0439-433 shows super-solar Mn/Fe. For several sub-DLAs at z<0.5, [N/S] is below the level expected for secondary N production, suggesting a delay in the release of the secondary N or a tertiary N production mechanism. We constrain the electron density using Si II* and C II* absorption. We also report different metallicity vs. Delta V_90 relations for sub-DLAs and DLAs. For two sub-DLAs with detections of emission lines from the underlying galaxies, our measurements of the absorption-line metallicities are consistent with the emission-line metallicities, suggesting that metallicity gradients are not significant in these galaxies.
description: 77 pages, 13 figures; accepted for publication in the Astrophysical Journal. Submitted (in the original form) May 26, 2014; accepted Apr. 15, 2015
The Dimension Six Triple Gluon Operator in Higgs+Jet Observables
Creators: name: Ghosh, Diptimoy
name: Wiebusch, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Recently a lot of progress has been made towards a full classification of new physics effects in Higgs observables by means of effective dimension six operators. Specifically, Higgs production in association with a high transverse momentum jet has been suggested as a way to discriminate between operators that modify the Higgs-top coupling and operators that induce an effective Higgs-gluon coupling---a distinction that is hard to achieve with signal strength measurements alone. With this article we would like to draw attention to another source of new physics in Higgs+jet observables: the triple gluon operator $O_{3g}$ (consisting of three factors of the gluon field strength tensor). We compute the distortions of kinematic distributions in Higgs+jet production at a 14 TeV LHC due to $O_{3g}$ and compare them with the distortions due to dimension six operators involving the Higgs doublet. We find that the transverse momentum, the jet rapidity and the difference between the Higgs and jet rapidity are well suited to distinguish between the contributions from $O_{3g}$ and those from other operators, and that the size of the distortions are similar if the Wilson coefficients are of the same order as the expected bounds from other observables. We conclude that a full analysis of new physics in Higgs+jet observables must take the contributions from $O_{3g}$ into account.
description: To appear as a Rapid Communication in Physical Review D
Flat space compressible fluid as holographic dual of black hole with curved horizon
Creators: name: Hao, Xin
name: Wu, Bin
name: Zhao, Liu
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider the fluid dual of $(d+2)$-dimensional vacuum Einstein equation either with or without a cosmological constant. The background solutions admit black hole event horizons and the spatial sections of the horizons are conformally flat. Therefore, a $d$-dimensional flat Euclidean space $\mathbb{E}^d$ is contained in the conformal class of the spatial section of the black hole horizon. A compressible, forced, stationary and viscous fluid system can be constructed on the product (Newtonian) spacetime $\mathbb{R}\times\mathbb{E}^d$ as the lowest order fluctuation modes around such black hole background. This construction provides the first example of holographic duality which is beyond the class of bulk/boundary correspondence.
description: 14 pages. V3: error corrections. To appear in JHEP
Additional file 2 of SAGA–CORE subunit Spt7 is required for correct Ubp8 localization, chromatin association and deubiquitinase activity
Creators: name: Nuño-Cabanes, Carme
name: García-Molinero, Varinia
name: Martín-Expósito, Manuel
name: María-Eugenia Gas
name: Oliete-Calvo, Paula
name: Encar García-Oliver
name: Iglesia-Vayá, María De La
name: Rodríguez-Navarro, Susana
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Figure S1. Sgf73 peptides detected by LC MS/MS and MASCOT in Sus1-TAP precipitates from different SAGA mutants. The middle region of Sgf73, which was recently found to contact SAGA-CORE subunits [17] is highlighted in blue. Some of the Sgf73 peptides found by LC MS/MS are highlighted in red. Figure S2. Levels of Ubp8 protein tagged with GFP in WT and spt7Δ mutant cells were analysed in three different experiments (1, 2 and 3) with two replicates of Ubp8-GFPspt7Δ in each (a and b) by western blotting of whole-cell extracts using an anti-GFP antibody. Levels of Pgk1 protein were also monitored and used as the loading control. Cropped blots are shown for clarity. Full-length blots are presented in Figure S6. Figure S3. Full-length blot that was cropped for Fig. 1e. Figure S4. Full-length blot that was cropped for Fig. 4a. Figure S5. Full-length blot that was cropped for Fig. 4c (upper and lower panels). Figure S6. Full-length blots that were cropped for Figure S2 (upper panel). Figure S7. Different full microscope images used in Figs. 2 and 3. Figure S8. Detailed GFP Fluorescence microscopic quantification using IPython notebooks. To determine significant values between different experimental groups, the mean data were compared using one-way analysis of variance (ANOVA). Tukey's multiple comparisons test was also used. Values of *p
Systemic Financial Risk Arising From Residential Flood Losses
Creators: name: Zeff, H.B.
name: Characklis, G.W.
name: Sebastian, A.
name: Thomson, H.
name: Kleiman, R.
Publisher: name: John Wiley and Sons Inc
Year: 2023

description: Direct damage from flooding at residential properties has typically been categorized as insured, with liabilities accruing to insurers, or uninsured, with costs accruing to property owners. However, residential flooding can also expose lenders and local governments to financial risk, though the distribution of this risk is not well understood. Flood losses are not limited to direct damages, but also include indirect effects such as decreases in property values, which can be substantial, though are rarely well quantified. The combination of direct damage and property value decrease influences rates of mortgage default and property abandonment in the wake of a flood, creating financial risk. In this research, property-level data on sales, mortgages, and insurance claims are used in combination with machine learning techniques and geostatistical methods to provide estimates of flood losses that are then utilized to evaluate the risk of default and abandonment in eastern North Carolina following Hurricane Florence (2018). Within the study area, Hurricane Florence generated $366M in observed insured damages and an estimated $1.77B in combined uninsured damages and property value decreases. Property owners, lenders, and local governments were exposed to an additional $562M in potential losses due to increased rates of default and abandonment. Areas with lower pre-flood property values were exposed to greater risk than areas with higher valued properties. Results suggest more highly resolved estimates of a flooding event's systemic financial risk may be useful in developing improved flood resilience strategies.
Demonstration of a memory for tightly guided light in an optical nanofiber
Creators: name: Gouraud, B.
name: Maxein, D.
name: Nicolas, A.
name: Morin, O.
name: Laurat, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We report the experimental observation of slow-light and coherent storage in a setting where light is tightly confined in the transverse directions. By interfacing a tapered optical nanofiber with a cold atomic ensemble, electromagnetically induced transparency is observed and light pulses at the single-photon level are stored in and retrieved from the atomic medium with an overall efficiency of (10 +/- 0.5) %. Collapses and revivals can be additionally controlled by an applied magnetic field. Our results based on subdiffraction-limited optical mode interacting with atoms via the strong evanescent field demonstrate an alternative to free-space focusing and a novel capability for information storage in an all-fibered quantum network.
Targeting Mitochondrial DNA Transcription by POLRMT Inhibition or Depletion as a Potential Strategy for Cancer Treatment
Creators: name: Graves, Lee M.
name: Fennell, Emily M. J.
name: Daglish, Sabrina C. D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Transcription of the mitochondrial genome is essential for the maintenance of oxidative phosphorylation (OXPHOS) and other functions directly related to this unique genome. Considerable evidence suggests that mitochondrial transcription is dysregulated in cancer and cancer metastasis and contributes significantly to cancer cell metabolism. Recently, inhibitors of the mitochondrial DNA-dependent RNA polymerase (POLRMT) were identified as potentially attractive new anti-cancer compounds. These molecules (IMT1, IMT1B) inactivate cancer cell metabolism through reduced transcription of mitochondrially-encoded OXPHOS subunits such as ND1-5 (Complex I) and COI-IV (Complex IV). Studies from our lab have discovered small molecule regulators of the mitochondrial matrix caseinolytic protease (ClpP) as probable inhibitors of mitochondrial transcription. These compounds activate ClpP proteolysis and lead to the rapid depletion of POLRMT and other matrix proteins, resulting in inhibition of mitochondrial transcription and growth arrest. Herein we present a comparison of POLRMT inhibition and ClpP activation, both conceptually and experimentally, and evaluate the results of these treatments on mitochondrial transcription, inhibition of OXPHOS, and ultimately cancer cell growth. We discuss the potential for targeting mitochondrial transcription as a cancer cell vulnerability.
Additional file 1 of Normative Values for Sport-Specific Left Ventricular Dimensions and Exercise-Induced Cardiac Remodeling in Elite Spanish Male and Female Athletes
Creators: name: Boraita, Araceli
name: Díaz-Gonzalez, Leonel
name: Valenzuela, Pedro L.
name: Heras, María-Eugenia
name: Morales-Acuna, Francisco
name: Castillo-García, Adrián
name: Lucia, María J.
name: Suja, Pedro
name: Santos-Lozano, Alejandro
name: Lucia, Alejandro
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Proportion of athletes with previous experience in the high competition ≤1 year and of athletes aged above 35 years, by sex and sport category.
Child as Method International Symposium Conference Proceedings
Creators: name: Carpes Barros Cassal, Luan
name: Christinaki, Artemis
name: Burman, Erica
name: Black, Laura
name: Wu, Weiyuan
Publisher: name: University of Manchester
Year: 2023
Subjects: classificationCode: 520102
subject: Educational psychology
classificationCode: 390302
subject: Early childhood education
classificationCode: 520101
subject: Child and adolescent development
classificationCode: 520505
subject: Social psychology
classificationCode: 500311
subject: Philosophical psychology (incl. moral psychology and philosophy of action)
classificationCode: 500320
subject: Psychoanalytic philosophy
classificationCode: 390304
subject: Primary education
classificationCode: 390306
subject: Secondary education
classificationCode: 390407
subject: Inclusive education
classificationCode: 390406
subject: Gender, sexuality and education
classificationCode: 390299
subject: Education policy, sociology and philosophy not elsewhere classified
classificationCode: 470211
subject: Migrant cultural studies
classificationCode: 470212
subject: Multicultural, intercultural and cross-cultural studies
classificationCode: 470299
subject: Cultural studies not elsewhere classified
classificationCode: 520303
subject: Counselling psychology
classificationCode: 440999
subject: Social work not elsewhere classified
classificationCode: 440712
subject: Social policy
classificationCode: 440502
subject: Feminist methodologies
classificationCode: 520105
subject: Psychological methodology, design and analysis
classificationCode: 441006
subject: Sociological methodology and research methods
classificationCode: 500302
subject: Critical theory

description: This three-day Symposium brought together academics working on Child as Method or more broadly interested in childhood studies, decolonial studies, postcolonial studies, psychology, psychoanalysis, critical studies, or education. We discussed experiences, challenges, and possibilities in using critical research approaches, besides developing new concepts and partnerships among researchers
Targeting the Divergent Roles of STK3 Inhibits Breast Cancer Cell Growth and Opposes Doxorubicin-Induced Cardiotoxicity In Vitro
Creators: name: Drewry, David H.
name: Nam, Jiung
name: Macias, Everardo
name: Loh, Chelsea
name: Schirmer, Amelia U.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: Breast cancer (BCa) is the most prevalent type of cancer in women. Several therapies used in the treatment of breast cancer are associated with clinically important rates of cardiovascular toxicity during or after treatment exposure, including anthracyclines. There is a need for new BCa therapeutics and treatments that mitigate chemotherapy-induced cardiotoxicity in BCa. In this study, we examine the effects of Serine/Threonine Kinase 3 (STK3) inhibition in the context of BCa therapy and cardioprotection from doxorubicin. STK3 (also known as MST2) is a key member of the Hippo Tumor-Suppressor Pathway, which regulates cell growth and proliferation by inhibiting YAP/TAZ co-transcription factors. Canonically, STK3 should restrict BCa growth; however, we observed that STK3 is amplified in BCa and associated with worse patient outcomes, suggesting a noncanonical pro-tumorigenic role. We found BCa cell lines have varying dependence on STK3. SUM52PE cells had the highest expression and dependence on STK3 in genetic and pharmacological assays. MCF-7 and MDA-MB-231 were less sensitive to STK3 targeting in standard proliferation assays, but were STK3 dependent in colony formation and matrigel invasion assays. In contrast, STK3 inhibition mitigated the toxic effects of doxorubicin in H9C2 rat cardiomyocytes by increasing YAP expression. Importantly, STK3 inhibition in BCa cells did not interfere with the therapeutic effects of doxorubicin. Our studies highlight STK3 is a potential molecular target for BCa with dual therapeutic effects: suppression of BCa growth and progression, and chemoprotection in cardiomyocytes.
Crisis bifurcations in plane Poiseuille flow
Creators: name: Zammert, Stefan
name: Eckhardt, Bruno
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Many shear flows follow a route to turbulence that has striking similarities to bifurcation scenarios in low-dimensional dynamical systems. Among the bifurcations that appear, crisis bifurcations are important because they cause global transitions between open and closed attractors, or indicate drastic increases in the range of the state space that is covered by the dynamics. We here study exterior and interior crisis bifurcations in direct numerical simulations of transitional plane Poiseuille flow in a mirror-symmetric subspace. We trace the state space dynamics from the appearance of the first three-dimensional exact coherent structures to the transition from an attractor to a chaotic saddle in an exterior crisis. For intermediate Reynolds numbers, the attractor undergoes several interior crises, in which new states appear and intermittent behavior can be observed. The bifurcations contribute to increasing the complexity of the dynamics and to a more dense coverage of state space.
Additional file 2 of Normative Values for Sport-Specific Left Ventricular Dimensions and Exercise-Induced Cardiac Remodeling in Elite Spanish Male and Female Athletes
Creators: name: Boraita, Araceli
name: Díaz-Gonzalez, Leonel
name: Valenzuela, Pedro L.
name: Heras, María-Eugenia
name: Morales-Acuna, Francisco
name: Castillo-García, Adrián
name: Lucia, María J.
name: Suja, Pedro
name: Santos-Lozano, Alejandro
name: Lucia, Alejandro
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 2: Cardiac geometry and left ventricular (LV) measures attending to the dynamic component of the sport in male athletes.
Additional file 1 of Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
Creators: name: Nia, Fatemeh Hassani
name: Woike, Daniel
name: Martens, Victoria
name: Klüssendorf, Malte
name: Hans-Hinrich Hönck
name: Harder, Sönke
name: Kreienkamp, Hans-Jürgen
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Additional file 1. Supplementary information.
Electroweak Baryogenesis in the Exceptional Supersymmetric Standard Model
Creators: name: Chao, Wei
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study electroweak baryogenesis in the E_6 inspired exceptional supersymmetric standard model ( E_6SSM ). The relaxation coefficients driven by singlinos and the new gaugino as well as the transport equation of the Higgs supermultiplet number density in the E_6SSM are calculated. Our numerical simulation shows that both CP-violating source terms from singlinos and the new gaugino can solely give rise to a correct baryon asymmetry of the Universe via the electroweak baryogenesis mechanism.
description: 13 pages, 3 figures
The COVID-19 Pandemic: Reflections of Science, Person, and Challenge in Academic Research Settings
Creators: name: Fitting, S.
name: Bidlack, J.M.
name: Meigs, D.D.
name: Yelamanchili, S.
name: Melendez, L.M.
name: Gorantla, S.
name: Sariyer, I.K.
name: Marcondes, M.C.G.
name: Gendelman, H.E.
name: Kumar, S.
name: Chang, S.L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2021

description: In spring of 2021, the Society on NeuroImmune Pharmacology (SNIP) organized a virtual workshop on the coronavirus disease 2019 (COVID-19). The daylong event’s fourth and final symposium, “Well-being and reflections,” offered a glimpse at the pandemic’s impact on the lives of our scientists and educators. This manuscript includes a brief summary of the symposium, a transcription of our incoming president Dr. Santosh Kumar’s lecture, titled “Intervention and improved well-being of basic science researchers during the COVID-19 era: a case study,” and the panel discussion that followed, “Reflection and sharing,” featuring Drs. Jean M. Bidlack, Sylvia Fitting, Santhi Gorantla, Maria Cecilia G. Marcondes, Loyda M. Melendez, and Ilker K. Sariyer. The conclusion of this manuscript includes comments from SNIP’s president Dr. Sulie L. Chang and our Chief Editor, Dr. Howard E. Gendelman. Drs. Sowmya Yelamanchili and Jeymohan Joseph co-chaired the symposium.