cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Organ Bioengineering Applied To Surgical Science
Creators: name: Peloso, Andréa
Publisher: name: Université de Genève
Year: 2024
Subjects: info:eu-repo/classification/ddc/617
Organ bioengineering
Regenerative medicine
Organ transplantation
ECM
Extra-cellular matrix

description:
Biomaterials, organ bioengineering and regenerative medicine are step-by-step revolutionizing general surgery and opening up innovative prospects in the treatment of several pathologic conditions. Organ bioengineering has rapidly gained attention as a promising solution to the organ shortage crisis for transplant. By combining biomaterials, stem cells biology and bioprinting technologies, researchers aim to create functional organs tailored to a patient's specific needs. Decellularization and cell-on-scaffold technology is one of the main avenues of research currently under investigation. This procedure consists of removing the cellular compartment from an organ, leaving behind an extracellular matrix-based scaffold, which could be then repopulated (recellularization) with the patient recipient's own cells. Decellularization/recellularization strategy, which avoids both the problem of lifelong immunosuppression and organ scarcity, has been successfully used to create bioengineered trachea, bladder and blood vessels. More recently it has been applied for the creation of more complex organs such as the liver, kidney and pancreas. In addition, organ bioengineering is proving to be a valuable tool for the development of preclinical surgical oncology models. Regenerative medicine and tissue and organ bioengineering have thus opened so far new frontiers in surgery; these advances have applications in tissue reconstruction, organ replacement and preclinical studies.

In the four studies presented, we show how organ bioengineering could be applied to liver, kidney and pancreas transplantation. Finally, we present a paper assessing the potential use of tridimensional hepatic extracellular matrix (ECM) for long-term in vitro culture envisioning 3D cell culturing for cancer bioengineering.

We lastly discuss our results and their perspectives for transplantation and surgical oncology sciences. As research in this field continues to advance, tissue and organ bioengineering are poised to have a growing importance in surgical science in the coming years by providing more effective and personalized curative strategies.
Additional file 10 of Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
Creators: name: Zhang, Sai
name: Diao, Jun
name: Qi, Chunmei
name: Jin, Jingjing
name: Li, Li
name: Gao, Xingjuan
name: Gong, Lei
name: Wu, Weiheng
Publisher: name: figshare
Year: 2018
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: The result of long-term nonfatal MI (Pâ =â 0.46; RR 1.32; 95%CI 0.63â 2.75). (DOCX 77 kb)
Species richness of the understory woody vegetation in Japanese cedar plantations declines with increasing number of rotations
Creators: name: Igarashi, Tetsuya
name: Masaki, Takashi
name: Nagaike, Takuo
name: Tanaka, Hiroshi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Plant Biology
subject: 60506 Virology

description: The possibility of restoring natural broadleaf forests may be decreased by the effects of plantation management, particularly in sites that undergo repeated rotation. We investigated the following two working hypotheses about the effects of repeated plantation of conifers on the natural regeneration of woody saplings in cool-temperate Japanese cedar plantations: (1) that repeated plantation of conifers decreases sapling species richness, and (2) that repeated plantation of conifers changes sapling species compositions. Our result supported the first hypothesis, because species richness was significantly lower in second-rotation plantations than in first-rotation plantations. The second hypothesis was not supported, because no significant or substantial differences in species composition were observed between plantations with different numbers of rotations. However, the abundance of tree (nonshrub) and gravity-dispersed species decreased after the second rotation of large saplings, albeit not those of small saplings, suggesting that response to repeated rotation depended on sapling size. Our results suggest that it is important to consider factors affecting the maintenance of a species in the plantations, such as distance from natural forests and seed sources, to minimize the effects of repeated plantation.
MOESM2 of Postprandial increase in serum CA125 as a surrogate biomarker for early diagnosis of ovarian cancer
Creators: name: Gu, Zhuowei
name: He, Yifeng
name: Zhang, Yue
name: Chen, Mo
name: Song, Keqi
name: Huang, Yuting
name: Li, Qing
name: Di, Wen
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Virology
subject: Computational Biology

description: Additional file 2: Figure S1â S3. Comparisons of the fluctuation patterns of blood glucose, serum insulin and CA125 between the ovarian cancer and non-cancer patients.Â Comparisons of relative CA125 and Mesothelin protein levels between ovarian cancer cells (OVCAR-3) treated with different agents, namely DMSO, insulin, insulin with high glucose, and insulin with high glucose and PI3K-Akt/MEK-Erk inhibitors. The time-dependent re-absorption of Alexa Fluor 488-labeled CA125 by ovarian cancer cells (OVCAR-3) under the high-glucose plus insulin condition.
Heavy thinning in hinoki plantations in Shikoku (southwestern Japan) has limited effects on recruitment of seedlings of other tree species
Creators: name: Mahoko Noguchi
name: Miyamoto, Kazuki
name: Okuda, Shiro
name: Takeharu Itou
name: Sakai, Atsushi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Heavy thinning may provide a feasible means to convert single-species coniferous plantations to broadleaved or mixed forests. To assess this possibility, we monitored tree seedling dynamics of other tree species, the understory microenvironment, and seed availability following heavy thinning (50 % by volume) in two hinoki (Chamaecyparis obtusa) plantations in Shikoku, southwestern Japan. Conventional (35 % by volume) and row thinning (50 % by volume) treatments were also applied at one of the sites. Diffuse transmittance in the understory dramatically increased after all thinning treatments then rapidly decreased, except after row thinning. Heavy thinning accelerated recruitment of small seedlings (with stems <30 cm high) at one of the sites. However, the densities of these seedlings declined sharply, and increases in the densities of larger seedlings recorded in subsequent surveys were very small. Furthermore, at the other site, recruitment of small seedlings under heavy thinning was equivalent to that under conventional thinning and lower than that under row thinning. Abundant species in the recruited seedlings were pioneer or subcanopy species found in the soil seed bank. Low seed rain density at both sites appeared to be responsible for the poor recruitment of canopy tree species. Our results suggest that heavy thinning had limited effects on the seedling recruitment of other tree species in these hinoki plantations due to insufficient seed rain and rapid canopy closure.
Addressing barriers to sexual and reproductive health services – insights from Switzerland and Cameroon
Creators: name: Schmidt, Nicole Christine
Publisher: name: Université de Genève
Year: 2024
Subjects: info:eu-repo/classification/ddc/618
Sexual and reproductive health
Health services
Migrants
Vulnerable populations
Qualitative research
Social determinants of health
Health literacy

description:
Universal access to sexual and reproductive health is a fundamental human right. However, access to sexual reproductive health services remains a challenge in many places of the world. First, sexual and reproductive health (SRH) services are not always available. Second, even in case of availability SRH services might not be accessed or utilized. Reasons are often multifactoral and difficult to disentangle as they range from individual factors (such as stigma, embarrassment, or fear) to structural barriers (e.g., the availability of transportation, costs but also policy regulations).

This thesis compromises four selected original publications exploring barriers to SRH services in two very different settings: a) migrant women in Geneva, Switzerland, consulting a gynecology or obstetrics department; b) women aged between 30 – 49 years, invited for cervical cancer screening, living in the Dschang district, Cameroon.

The collection aims to review the previous research work with a more global approach. Hereby, the principal objective is - despite the different settings’- to explore common barriers to SRH services. Furthermore, the secondary objective is to understand whether classifying the encountered limiting factors in the Dahlgren and Whitehead model of social determinants is helpful to identify additional interventions or research opportunities for SRH services or programs.

In conclusion, the selected publications revealed three common barriers to SRH services: financial considerations, insufficient quality of SRH services and the inadequate comprehension of SRH services. Despite the limitations of the Dahlgren and Whitehead model, the utilization of the framework allowed to suggest additional interventions or research opportunities for the two healthcare settings. Those were identified as direct interventions on the level of healthcare professionals providing SRH care; specifically, the implementation of training to (i) address discrimination and stigma and (ii) to improve the quality of communication of healthcare professionals. (Figure 5) Furthermore, research opportunities were mainly suggested at the programmatic management level of SRH services health programs or institutions. Hereby, future research was especially suggested to (i) analyze forms and levels of discrimination and stigma (ii) quantify and evaluate specific health literacy interventions e.g., the usability of universal precaution tools and (iii) explore the role of indirect costs as a barrier to SRH services.
GENDER MAINSTREAMING AND WOMEN EMPOWERMENT IN IRAN: A SOCIO-CULTURAL, POLITICAL & ECONOMIC PE RSPECTIVE
Creators: name: MWANIKI, MILLY WAIRIMU
Publisher: name: Zenodo
Year: 2024
Subjects: Gender Mainstreaming, Women Empowerment, Feminism, International Relations, Gender Equality.

description: Abstract

The objective of this study is to outline a detailed understanding of economic, political, socio-cultural influence on empowerment and how it is applied strategically in supporting successful financial independence, freedom and social transformation for women. Iran being the case study for this particular research. Gender Mainstreaming is significant at ensuring focus is directed to the women empowerment agenda as they tend to face unique barriers and also continue to lag behind across major development indicators. The article explains the identities of women in Iran and how the interactions from a Feminism perspective changed or shapes various politics and policies in the country. It shows how alliance of feminists as well as non-feminists in Iran contributed to gender awareness, social transformation and shaped politics on a basis of shared goals and aspirations.
Beyond monitoring: from data to action in surgical site infection surveillance
Creators: name: Abbas, Mohamed
Publisher: name: Université de Genève
Year: 2024
Subjects: info:eu-repo/classification/ddc/616
Surgical site infections
Surveillance
Healthcare-associated infections

description:
Surgical site infections (SSI) are significant postoperative complications and a leading cause of healthcare-associated infections (HAI) worldwide. They are associated with excess morbidity and mortality, and lead to decreased quality of life, prolonged hospital length of stay, and increased costs. Surveillance of HAI, including SSI, is a cornerstone of effective infection prevention and control (IPC) programmes. Surveillance activities can guide the implementation, and assess the effectiveness of preventive programmes aimed at reducing SSI incidence. In this Privat-Docent thesis we include four publications that contribute a unique perspective to SSI surveillance.

The first publication addresses the intrinsic effect of surveillance. We performed a large international cohort study of SSI surveillance networks in 15 countries, and were able to determine that a hospital’s duration of participation in a surveillance network was associated with a decrease in its SSI incidence. This study confirms the existence of the “surveillance effect”, implying that awareness and monitoring can drive improvements in clinical practice and outcomes.

The second publication examines the temporal trends and epidemiology of SSI due to Staphylococcus aureus in Switzerland, using data from the Swiss SSI surveillance network (Swissnoso), and showed that there were decreasing trends in incidence. We also examined risk factors associated with both methicillin-susceptible and methicillin-resistant S. aureus, helping to inform targeted prevention approaches, and to identify high-risk populations for further studies.

The third publication used data from SSI surveillance networks in England, France, and Switzerland to externally validate risk predictions scores for SSI in colorectal surgery, where the burden is the highest, and to develop a novel score. The study highlighted the limitations of current models and underscores the need for more accurate prediction tools, which rely on data that is beyond what is routinely collected for the purposes of surveillance.

The fourth publication charts a strategic roadmap, developed by a multidisciplinary group of European experts in surveillance, for the transition to automated HAI surveillance across Europe, including SSI. It emphasises benefits for surveillance practices that are brought about by digitalisation and automation in terms of efficiency and standardization, but also discusses common challenges and key questions such as surveillance targets. It is intended to accompany individuals or institutions that wish to implement an automated HAI surveillance programme.
Scaling-up from tree to stand transpiration for a warm-temperate multi-specific broadleaved forest with a wide variation in stem diameter
Creators: name: Chiu, Chen-Wei
name: Komatsu, Hikaru
name: Katayama, Ayumi
name: Otsuki, Kyoichi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Previous studies have demonstrated a clear relationship between diameter at breast height (DBH) and tree transpiration (QT) in multi-specific broadleaved forests. However, these studies were conducted with a limited range of tree sizes and species, and thus many multi-specific broadleaved forests fall outside these conditions. Therefore, this study examined the relationship between DBH and QT in a warm-temperate multi-specific broadleaved forest (n = 12 species) with a wide range of tree sizes (5.0–70.0 cm DBH) using the Granier-type heat dissipation method. The results showed that, although sap flow density varied between individual trees and species, there was a significant relationship between log QT and log DBH (r2 = 0.66, P < 0.001) because of the strong dependence of sapwood area on DBH. This study confirmed the applicability of the relationship for the stand transpiration (EC) estimates even in a multi-specific broadleaved forest with a wide variation in DBH. Our results also revealed that selecting the sample trees in descending order of DBH effectively reduced potential errors in EC estimates for a specific sample size, as larger trees contribute more to EC. This information should be useful for future studies investigating the transpiration of multi-specific broadleaved forests, reducing errors during the scaling-up procedure.
title: Volcanic structures and magmatic evolution of the Vesteris Seamount, Greenland Basin
Creators: name:  Moreno,   Katharina Anna Unger
name:  Thal ,   Janis
name:  Bach ,   Wolfgang
name:  Beier ,   Christoph
name:  Haase ,   Karsten Matthias
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: The solitary intraplate volcano Vesteris Seamount is located in the Central Greenland Basin and rises around 3000 m above the seafloor with a total eruptive volume of ~500 km3. Newly acquired high-resolution bathymetry allows through backscatter data and raster terrain analysis to distinguish several volcanic structures. The Vesteris Seamount is a northeast to southwest elongated stellar-shaped seamount with an elongated, narrow summit radially surrounded by irregular volcanic ridges, separated by volcanic debris fans. Whole rock geochemical data of 78 lava samples form tight liquid lines of descent with MgO concentrations ranging from 12.6 to 0.1 wt. %, implying that all lavas evolved from a similar parental magma composition. Video footage from ROV dives show abundant pyroclastic deposits on the summit and on the flanks whereas lavas are restricted to flank cones and dike intrusions. The seamount likely forms above a crustal weak zone and the local volcanic stress field increasingly affects the constructive and destructive features on the surface. The evolution of Vesteris Seamount reflects the transition from deep, regional crustal stresses in the older features to local, volcanic stresses in the younger structural features. The Vesteris Seamount enables to understand the structural and magmatic evolution of intraplate volcanoes distant from plate boundaries by combining detailed geological sampling, high-resolution bathymetry and underwater video coverage.
title: The correlation of radon in different types of buildings and radon prone areas of Cluj-Napoca, Romania.
Creators: name:  Pap(1) ,   István Mihály
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: It is a well-known fact that the city of Cluj-Napoca in Romania has a diverse geological stratification, based on the geological data and studies performed on the soil by geologists. Also, the measurements and studies performed of radon in soil conclude the fact that in certain parts, the geological formations lead to a higher concentration of geogenic radon, thus making the soil in this area a radon prone hotspot. The following presentation aims to show the correlations between the radon prone geological areas and the accumulation of high concentrations (indoor radon) in different types of buildings, regarding a few examples of residential buildings like houses and big building categories such as public institutions. The studies performed so far show different accumulation between buildings, but even the way that certain buildings were built in the same area where the soil has a high radon potential. This shows that even if the population builds in high radon prone areas, there is a way to build buildings, following radon building guidelines to limit the diffusion of radon trough out the foundation of the building or even blocking it completely. There are three key factors when talking about a high radon concentration risk exposure indoors, that are the following: the radon potential in the soil where the building is built, the way and techniques used to build the certain building and the way the building is used on a daily bases.
Changes in aboveground and belowground properties during secondary natural succession of a cool-temperate forest in Japan
Creators: name: Hyodo, Fujio
name: Haraguchi, Takashi F.
name: Muneto Hirobe
name: Tateno, Ryunosuke
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Forest development in temperate regions is considered to be a global carbon sink. Many studies have examined forest development after harvesting or fire from aboveground (e.g., biomass) or belowground (e.g., soil nutrient) perspectives. However, few studies have explored forest development from both perspectives simultaneously in cool-temperate forests in Japan. In this study, we examined changes over 105 years in both aboveground and belowground components during secondary natural succession. The aboveground biomass increased for 50 years and reached a plateau in a 105-year-old stand. The N mineralization rate increased during succession for 50 years, but showed a decline in the 105-year-old stand due to the decrease in the nitrification rate in late succession. The percent nitrification (i.e., relative contribution of nitrification to N mineralization) decreased significantly with increasing forest stand age. The N mineralization rates had significant relationships with N concentrations of the dominant tree foliage and litter fall and with the amount of litter fall N. Meanwhile, other belowground properties (i.e., soil pH, phenol concentration, soil microbial respiration, and litter mass loss) did not show any significant relationship with forest stand age. This may be because the soil at the study sites was heterogeneous and consisted of Cambisols and Andosols, the latter of which originally has high organic matter content, and thus may have buffered the effect of the aboveground development. These results indicate that belowground N dynamics are more closely associated with aboveground development than other belowground properties in these forests.
Additional file 11 of Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
Creators: name: Zhang, Sai
name: Diao, Jun
name: Qi, Chunmei
name: Jin, Jingjing
name: Li, Li
name: Gao, Xingjuan
name: Gong, Lei
name: Wu, Weiheng
Publisher: name: figshare
Year: 2018
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: The result of long-term MACE (Pâ <â 0.001; RR 2.49; 95%CI 1.47â 4.23). (DOCX 86 kb)
Mapping the relative risk of surface water acidification based on cumulative acid deposition over the past 25 years in Japan
Creators: name: Yamashita, Naoyuki
name: Sase, Hiroyuki
name: Ohizumi, Tsuyoshi
name: Kurokawa, Junichi
name: Ohara, Toshimasa
name: Morino, Yu
name: Kuribayashi, Masatoshi
name: Ohta, Seiichi
name: Kaneko, Shinji
name: Hayashi, Kentaro
name: Fukuhara, Haruo
name: Hakamata, Tomoyuki
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Sensitivity maps of atmospheric acid deposition in Japan have not been updated in 20 years. Here, we propose new relative risk maps of surface water acidification in forests based on a weighted overlay of cumulative potential acid deposition (CPAD) simulated for a 25-year period (1981–2005), including the sensitivities of soil and bedrock to acidification. We assumed that relative acidification risk is high in areas that exhibit high sensitivities of soil and bedrock to acid and have received a large amount of cumulative acid deposition over the past several decades. We aggregated fine soil and bedrock maps into a 20-km mesh for overlay onto an 80-km mesh map of CPAD by considering their spatial structures in Japan. Allocation of the weights among CPAD and soil and bedrock sensitivities was performed based on observational trends in river pH over the past 30 years. The resulting risk map for surface water acidification showed that large areas of western Japan, as well as smaller areas of Hokkaido, Tohoku, Kanto, and Kyushu, are at high risk of surface water acidification. Seventy-seven percent of all rivers for which a declining trend in pH was observed from 2001 to 2009 were also high-risk areas. Acid deposition might be one factor controlling surface water acidification in areas with high bedrock sensitivity, in addition to high CPAD and soil sensitivity, although the risk of soil acidification remains unclear.
„Auf Augenhöhe ..."
Creators: name: Gätjen, Jochen
name: Jakobs, Dörthe
name: Jenisch, Bertram
name: Kielmann, Dunja
name: Kriszt, Sandra
name: Kronz, Andreas
name: Parello, Daniel
Publisher: name: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege
Year: 2024

description: Denkmalpflege in Baden-Württemberg – Nachrichtenblatt der Landesdenkmalpflege, Bd. 53 Nr. 1 (2024)
Ecological implications of mammal feces buried in snow through dung beetle activities
Creators: name: Enari, Hiroto
name: Koike, Shinsuke
name: Sakamaki-Enari, Haruka
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology

description: In early spring, snow-buried mammal feces simultaneously emerge on the ground with the melting of the snow across regions with heavy snowfall. Here, we evaluated the ecological implications of this phenomenon for the cool-temperate forest ecosystem in terms of the resource use of dung beetles (Coleoptera: Scarabaeidae), which play key roles in secondary seed dispersal and nutrient cycling. During May 2012 and 2013, we conducted cafeteria experiments in heavy snowfall regions with different types of forest cover in northern Japan by using pitfall traps baited with the snow-buried feces of Japanese macaques (Macaca fuscata), Japanese serows (Capricornis crispus), and Japanese hares (Lepus brachyurus angustidens). From the experiments, we identified 12 dung beetle species, indicating that the snow-buried feces could act as a valuable resource for vernal beetles. Most of the beetles had obvious fecal preferences. The snow-buried feces of serows were widely available resources for most vernal species, including dwellers and tunnelers, contributing to the biomass of those species. Although dung beetles using snow-buried feces in young broadleaf forests with rich feces supplies did not always exhibit the highest species richness, tunnelers frequently emerged in those forests, and Phelotrupes preferred macaque feces. This finding could have important implications for plant regeneration, as it relates to time-lagged mammal–beetle interactions. Endozoochorous seeds dispersed by macaques in the autumn have insufficient opportunities for secondary seed dispersal by beetles as the beetles are inactive in autumn, but those seeds are protected against predation by snow during winter and are safely preserved under soil by vernal tunnelers.
D8.3 – Supporting Aggregators at Third-party Installations (OpenAIRE D-NET Software-Toolkit As-a- Service)
Creators: name: Manghi, Paolo
name: Atzori, Claudio
name: Bardi, Alessia
Publisher: name: Zenodo
Year: 2019

description: The OpenAIRE technical infrastructure includes services dedicated to the aggregation of metadata
 about objects of the research life-cycle for the materialization of a scholarly communication graph.
 Being aware of the challenges to face when designing, implementing and operating a big metadata
 aggregative infrastructure, OpenAIRE aims at providing its technologies to third parties (e.g.
 National Contact Points (NCP) like ministries and libraries, research communities, research
 initiatives, national and regional aggregators) in order to facilitate the realization of sustainable
 metadata aggregative infrastructures in Europe and beyond, which can benefit with off the shelf
 interoperability with the OpenAIRE infrastructure services.
 This document describes the several options that OpenAIRE offers to third parties to exploit
 OpenAIRE’s aggregator enabling framework based on the D-NET Software Toolkit and the
 OpenAIRE Broker Service.
Additional file 12 of Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
Creators: name: Zhang, Sai
name: Diao, Jun
name: Qi, Chunmei
name: Jin, Jingjing
name: Li, Li
name: Gao, Xingjuan
name: Gong, Lei
name: Wu, Weiheng
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: The result of long-term all mortality (Pâ <â 0.001; RR 3.82; 95% CI 2.94â 4.96). (DOCX 57 kb)
Structural data and immunomodulatory properties of a water-soluble heteroglycan extracted from the mycelium of an Italian isolate of Ganoderma lucidum
Creators: name: Carrieri, Raffaele
name: Manco, Rosanna
name: Sapio, Daniela
name: Iannaccone, Marco
name: Fulgione, Andrea
name: Papaianni, Marina
name: Falco, Bruna De
name: Grauso, Laura
name: Tarantino, Paola
name: Ianniello, Flora
name: Lanzotti, Virginia
name: Lahoz, Ernesto
name: Capparelli, Rosanna
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology

description: Mushrooms produce a wide range of bioactive polysaccharides, different from each other in chemical structure and biological effects. In the last years, the idea to develop functional foods or drugs containing fungal polysaccharides is attracting great attention. Fruiting bodies of Basidiomycetes Ganoderma lucidum are commonly used in Oriental medicine to treat several disorders. G. lucidum polysaccharides – mainly β-glucans and heteroglycans – have numerous biological properties such as antitumour and immunomodulatory activities. This report shows, by gene expression analyses and bioenergetic assays, immunomodulatory properties and capacity to improve glucose metabolism of a water-soluble heteroglycan extracted from mycelium of an Italian isolate of G. lucidum. The findings suggest the use of the heteroglycan as probiotic or ingredient in functional foods, being easy to produce and disperse in a food matrix thanks to its water-solubility. Heteroglycan could exert protective effects in pro-inflammatory conditions and benefits for people characterised by suppressed immune response.
Facilitating the Adoption and Evolution of Digital Technologies Through Re-conceptualization.
Creators: name: Tekkis, Nicholas Pari
name: Richmond-Smith, Rebecca
name: Pellino, Gianluca
name: Kontovounisios, Christos
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Imaging
Innovation
Healthcare System
3D Printing
Layered Modular Architecture

description: BackgroundThe NHS has been making steps toward greater efficiency and cutting costs to maintain quality of care despite constraints, but without innovation the NHS will not be able to meet its increasing financial demands. The purpose of this article is to analyse a single potentially transformative technology's path of adoption in the NHS [3D printing (3DP)].MethodsAnalysis of 3DP and its current value propositions. Re-conceptualization of the technology to gain insights into these value propositions and identify the capabilities it may provide. Analysis of previous business models to identify where this value is not fully captured and development of a new business model, followed by exploration of benefits and potential limitations of this new model.Results3D printing applications can be broadly categorized into anatomical modeling, implants, and tools. Conceptualizing 3D imaging using the layered architecture model suggests the potential of 3DP to evolve the current imaging and modeling infrastructure of the NHS, and as such should be adopted to facilitate this potential.Conclusion3D printing is an innovation with large potential for generativity, and it is important that it is integrated at a level that could both stimulate and communicate its benefits. Re-conceptualization identified a backbone within the NHS that could facilitate it as a point of entry, and the most successful installations have been through this channel. However, progress on the frontier is currently limited by both physical and organizational boundaries, the resolution of which is paramount for the current and future success of this technology.
Predicting load path and tensile forces during cable yarding operations on steep terrain
Creators: name: Dupire, Sylvain
name: Bourrier, Franck
name: Berger, Frédéric
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Cable yarding systems constitute an adapted solution for steep-slope harvesting in mountain forests. However, it requires many specific skills for both forest managers and operators. The objectives of this research were to: (1) develop a CableHelp model for the set-up of cable yarding systems where inputs are operational field data and outputs are load path and tensile forces, and (2) to validate it with field experiments. The results show a high accuracy between the data predicted by the model and field measurements. Furthermore, this work stresses the importance of taking into account both the mainline effect and the friction between skyline and intermediate supports to properly calculate the skyline tension and load path. The CableHelp model shows great adaptability and ensures highly accurate predictions for any position on the line profile and for different configurations: single-span or multiple-span profiles, uphill or downhill yarding and for different kinds of carriage. A direct application of this research is to optimize the set-up of cable lines in order to reduce equipment wear, as well as operating cost, while respecting operator safety.
Additional file 1 of Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
Creators: name: Zhang, Sai
name: Diao, Jun
name: Qi, Chunmei
name: Jin, Jingjing
name: Li, Li
name: Gao, Xingjuan
name: Gong, Lei
name: Wu, Weiheng
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology

description: The result of advanced HF (Pâ <â 0.001; RR 1.81; 95%CI 1.48â 2.21). (DOCX 41 kb)
Additional file 2 of Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
Creators: name: Zhang, Sai
name: Diao, Jun
name: Qi, Chunmei
name: Jin, Jingjing
name: Li, Li
name: Gao, Xingjuan
name: Gong, Lei
name: Wu, Weiheng
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology

description: The result of Angina(Pâ =â 0.007; RR 1.67; 95%CI 1.15â 2.41). (DOCX 41 kb)
Secondary metabolites with antiproliferative effects from Albizia glaberrima var glabrescens Oliv. (Mimosoideae)
Creators: name: Fotso, Ghislain Wabo
name: Kamga, Justin
name: Bathelemy Ngameni
name: Uesugi, Shota
name: Ohno, Misa
name: Ken-Ichi Kimura
name: Momma, Hiroyuki
name: Eunsang Kwon
name: Furuno, Hiroshi
name: Shiono, Yoshihito
name: Ingrid, Simo K.
name: Yeboah, Samuel O.
name: Ngadjui, Bonaventure T.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: A new 5-dehydroxyflavan, namely Albiziaflavan B or (+)-(2R, 3S, 4R)-3′,4′, 7-trihydroxy-4-methoxy-2,3-trans-flavan-3,4-trans-diol (1) was isolated from the root bark of Albizia glaberrima, together with six known compounds including three flavans: (+)-mollisacacidin (2), (+)-fustin (3) and butin (4); two steroids: chondrillasterol (5) and chondrillasterone (6), and a triterpenoid: lupeol (7). The structure of 1 was established by detailed analysis of its spectroscopic data, especially 1D and 2D NMR spectra, HRESIMS and CD data. Compounds 1–6 were assayed for their antiproliferative effects on two human cancer cells, HeLa at 50 μM (n = 2) and HL60 at 20 μM (n = 2). Compound 3 and 4 were the most active on HL60 with IC50 of 8.1 and 8.3 μM, respectively. Compound 6 was the most active with an IC50 of 4.6 μM on HeLa.
A novel benzimidazole and other constituents with antiproliferative and antioxidant properties from Thymelaea microphylla Coss. et Dur
Creators: name: Noman, Labib
name: Oke-Altuntas, Feyza
name: Zellagui, Amar
name: Ayse Sahin Yaglioglu
name: Demirtas, Ibrahim
name: Cardoso, Susana M
name: Akkal, Salah
name: Noureddine Gherraf
name: Rhouati, Salah
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: A new compound (microphybenzimidazole, 7) along with the six known compounds matairesinol (1), prestegane B (2), umbelliferone (3), daphnoretin (4), microphynolide A (5) and microphynolide B (6) were isolated from Thymelaea microphylla. The structures of the pure compounds were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2D-NMR, and HPLC-TOF/MS. Compounds 2 and 4, as well as three fractions (F6, F6-C5, and F6-W42) obtained from a 50% (v:v) CH2Cl2:MeOH extract exhibited a selective activity against rat brain glioma cells (C6). Moreover, compound 1 and other fractions obtained from 50% (v:v) CH2Cl2:MeOH and 70% (v:v) MeOH:H2O extracts exhibited dose- and time-dependent effects on human cervical cancer cell (HeLa), as measured by xCELLigence assay. Compound 2 (IC50 = 14.0 ± 0.2 μg/mL) and fraction F5 (IC50 = 12.4 ± 0.1 μg/mL) showed higher radical scavenging ability than the synthetic agent butylated hydroxytoluene (BHT, IC50 = 22.7 ± 0.6 μg/mL)
title: 3D geological modeling of graben structures in northern Hesse – concept, methods and first results
Creators: name:  Lewin,   Ina
name:  Lehné ,   Rouwen
name:  Heggemann ,   Heiner
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: For some years now, the Hessian Agency for Nature Conservation, Environment and Geology (HLNUG) is focusing its 3D-modeling activities on urban areas, aiming to contribute to both integrated modeling and urban planning (e.g., Lehné et al. 2017, Lehné et al. 2013, Budde et al. 2017). Experiences gained in the frame of the project “Darmstadt_3D”, which is delivering the urban subsurface including the technical infrastructure (sewage system, foundations, etc.), now are adopted for a working area in northern Hesse, southeast of Kassel. Geologically it is located in the Hessian depression and mainly characterized by WNW-ESE trending graben system of Kassel, and major features perpendicular to the main direction of the graben structure. The just emerging 3D geological model is addressing the stratigraphic horizons Quaternary, Tertiary as well as the lower triassic formations Röt, Solling and Hardegsen and based on 449 quality checked drillings, of which several also have been used for the construction of 8 cross sections that help to better elaborate the fault network. In addition, geological maps and already existing cross sections are considered. First results show a complex tectonic situation with displacement rates that often exceed 100m. They also confirm the conceptual approach to be expedient and suitable for the intended extension of the working area to the area of Kassel. On the way the geological 3D-content will be parameterized for downstream applications such as modeling groundwater, and radon potentials as well as enriched by urban subsurface infrastructure in order to get a fully integrated urban 3D-information system.
Validity and reliability of a novel measure of activity performance and participation
Creators: name: Murgatroyd, Phil
name: Karimi, Leila
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Purpose: To develop and evaluate an innovative clinician-rated measure, which produces global numerical ratings of activity performance and participation. Method: Repeated measures study with 48 community-dwelling participants investigating clinical sensibility, comprehensiveness, practicality, inter-rater reliability, responsiveness, sensitivity and concurrent validity with Barthel Index. Results: Important clinimetric characteristics including comprehensiveness and ease of use were rated >8/10 by clinicians. Inter-rater reliability was excellent on the summary scores (intraclass correlation of 0.95–0.98). There was good evidence that the new outcome measure distinguished between known high and low functional scoring groups, including both responsiveness to change and sensitivity at the same time point in numerous tests. Concurrent validity with the Barthel Index was fair to high (Spearman Rank Order Correlation 0.32–0.85, p > 0.05). The new measure’s summary scores were nearly twice as responsive to change compared with the Barthel Index. Other more detailed data could also be generated by the new measure. Conclusions: The Activity Performance Measure is an innovative outcome instrument that showed good clinimetric qualities in this initial study. Some of the results were strong, given the sample size, and further trial and evaluation is appropriate.Implications for RehabilitationThe Activity Performance Measure is an innovative outcome measure covering activity performance and participation.In an initial evaluation, it showed good clinimetric qualities including responsiveness to change, sensitivity, practicality, clinical sensibility, item coverage, inter-rater reliability and concurrent validity with the Barthel Index.Further trial and evaluation is appropriate. The Activity Performance Measure is an innovative outcome measure covering activity performance and participation. In an initial evaluation, it showed good clinimetric qualities including responsiveness to change, sensitivity, practicality, clinical sensibility, item coverage, inter-rater reliability and concurrent validity with the Barthel Index. Further trial and evaluation is appropriate.
Techniki rekomendacyjne we współczesnym marketingu
Creators: name: Malinowski, Michał
name: Krysiński, Stanisław
Publisher: name: figshare
Year: 2022
Subjects: subject: 150301 Business Information Management (incl. Records, Knowledge and Information Management, and Intelligence)
subject: FOS: Economics and business
subject: 150302 Business Information Systems
subject: 159999 Commerce, Management, Tourism and Services not elsewhere classified

description: This study provides an overview of contemporary marketing issues, in particu-lar one of its auxiliary tools, such as the area of recommendations. Due to the hugedevelopment of the Internet, both in terms of geography and its using possibilitiesin everyday life, huge amounts of data are collected. It is not possible to analyzesuch a data set with traditional methods, that’s why it makes necessary to searchfor and use more modern methods. Such methods are provided by recommendationarea. The first part of the article presents a look at contemporary marketing, then introduces the area of recommendations and its basic elements. The last part hasa practical dimension and is related to issues arising from the implementation andoperation of recommendation systems in e-commerce solutions.
Additional file 3 of Predictive value of neutrophil to lymphocyte ratio in patients with acute ST segment elevation myocardial infarction after percutaneous coronary intervention: a meta-analysis
Creators: name: Zhang, Sai
name: Diao, Jun
name: Qi, Chunmei
name: Jin, Jingjing
name: Li, Li
name: Gao, Xingjuan
name: Gong, Lei
name: Wu, Weiheng
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Hematology

description: The result of arrhythmia (Pâ =â 0.002; RR 1.38; 95% CI 1.13â 1.69). (DOCX 47 kb)
Rising Times at Sphaera Recta - Ptolemy's Almagest by Toomer (Gerald J.) (1984) | Type-B (ID n° 182)
Creators: name: Toomer, Gerald J.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Astronomy
Medieval history

description: This is a type B edition: A type-B edition corresponds to a critical edition of several table witnesses:
 it is based on several different editions, themselves based on tables from different primary sources.
 A type-B edition can be based on type-A, type-B or type-C editions.
You can find it on the DISHAS project website from this link: https://dishas.obspm.fr/table-edition/182
description: Source: Ptolemy's Almagest, Toomer (Gerald J.), 1984
title: Diapositives de présentation du projet ICCARRE associées à la communication donnée à l'ISHEID Congress 2014
Creators: name: Leibowitch, Jacques
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/Calames-20193111135767413
description: created: start=1975;end=2018