cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Conformational Transitions in the Membrane Scaffold Protein of Phospholipid Bilayer Nanodiscs
Creators: name: Morgan, Christopher R.
name: Engen, John R.
name: Rand, Kasper D.
name: Stafford, Darrel W.
name: Jorgenson, James W.
name: Hebling, Christine M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Phospholipid bilayer nanodiscs are model membrane systems that provide an environment where membrane proteins are highly stable and monodisperse without the use of detergents or liposomes. Nanodiscs consist of a discoidal phospholipid bilayer encircled by two copies of an amphipathic alpha helical membrane scaffold protein, which is modeled from apolipoprotein A-1. Hydrogen exchange mass spectrometry was used to probe the structure and dynamics of the scaffold protein in the presence and absence of lipid. On nanodisc self-assembly, the entire scaffold protein gained significant protection from exchange, consistent with a large, protein-wide, structural rearrangement. This protection was short-lived and the scaffold protein was highly deuterated within 2 h. Several regions of the scaffold protein, in both the lipid-free and lipid-associated states, displayed EX1 unfolding kinetics. The rapid deuteration of the scaffold protein and the presence of correlated unfolding events both indicate that nanodiscs are dynamic rather than rigid bodies in solution. This work provides a catalog of the expected scaffold protein peptic peptides in a nanodisc-hydrogen exchange mass spectrometry experiment and their deuterium uptake signatures, data that can be used as a benchmark to verify correct assembly and nanodisc structure. Such reference data will be useful control data for all hydrogen exchange mass spectrometry experiments involving nanodiscs in which transmembrane or lipid-associated proteins are the primary molecule(s) of interest.
Pinto de Oliveira, C. J., Information et propagande. Responsabilités chrétiennes. Ed. Du Cerf. Vol. de 415 ps. 132x195. Paris 1968
Creators: name: Ferraz, Agostinho Moreira
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
In Search of the Legal Boundaries of an “Open Society”. The Case of Immigrant Integration in the EU
Creators: name: Vitiello, Daniela
Publisher: name: Universita' degli Studi di Salerno
Year: 2022
Subjects: Open society
Integration clauses
Civic integration
Non discrimination
EU competence

description: Diversity and pluralism are embedded in the political project of the Union as based on the archetype of a liberal “open society”. At the same time, the preservation and promotion of these values is being increasingly challenged, especially in the fields of EU competence which are traditionally more sensitive to the calls for sovereignty, such as on migration and asylum policies. This article takes the EU immigrant integration policy as a case study to test the legal boundaries of the European open society. It departs from the limits of the EU competence in this field of action to demonstrate that the self-restraint of the European Union in the development of “a more vigorous integration policy” has been first and foremost a political option. This option has magnified the tension embedded in the legal design of the AFSJ and the CEAS, minimising the correlation between successful integration paths and effective immigration and asylum policies. This evidence should induce the Union – within the remit of its own competence – to greater activism in support of TCN integration and inclusion in the European open society.
L'acropoli. Volume II (1946)
Creators: name: (:Unkn) Unknown
Publisher: name: Napoli : Gaetano Macchiaroli
Year: 1946

description: N. 13 (gennaio 1946): Omodeo, A., La distruzione delle classi medie, P. 7 ; Bracci, M., Aspetti negativi del Partito d'Azione, P. 12 ; Martinazzoli, F., Irreligiosità e anticlassicismo di Dewey, P. 17 ; Alfieri, V. E., Difesa dell'antifascismo, P. 29 ; La Jugoslavia tra il fatto e il diritto (Riccardo Longone), P. 35 ; Estratti dalla Stampa italiana e straniera ; Rassegne ; In Corsivo.
description: N. 14 (febbraio 1946): Saluto a Benedetto Croce, P. 53 ; Omodeo, A., La politica estera alla Consulta, P. 54 ; Santonastaso, G., La proprietà e il socialismo, P. 61 ; Pesenti, A., Schemi e realtà del comunismo, P. 67 ; Omodeo, A., Giovanni Calvino progenitore di libertà, P. 76 ; I comunisti e la riforma agraria (Nicola De Simone), P. 86 ; Estratti dalla Stampa italiana e straniera ; Rassegne ; In Corsivo.
description: N. 15 (marzo 1946): Omodeo, A., La frattura del Partito d'Azione, P. 101 ; Themelly, M., Liberalismo e democrazia in Mazzini, P. 107 ; Pepe, G., Attualità di Mazzini, P. 115 ; Omodeo, A., Il concetto mazziniano di popolo, P. 123 ; Benes, E., La Cecoslovacchia tra Oriente e Occidente, P. 129 ; Problemi della riforma agraria (Nicola De Simone), P. 133 ; Estratti dalla Stampa italiana e straniera ; Rassegne ; In Corsivo.
description: N. 16 (aprile 1946): Galante Garrone, A., Guerra partigiana in Italia, P. 149 ; Pepe, G., Lo scisma liberale, P. 165 ; Bobbio, N., Di un nuovo esistenzialismo, P. 171 ; Abbate, M., Confessioni di un giovane liberale, P. 182
description: [Ultimo fascicolo dedicato a ]L'Acropoli ad Adolfo Omodeo: Commiato, P. II, Calamandrei, P., Dignità del vivere, P. III ; Croce, B., L'opera che fu nostra, P. VI ; Salvatorelli, L., Gli studi di storia, P. XI, Galante Garrone, A., L'ultimo grande seguace di Mazzini, P. XXI, Pepe, G., II pensiero politico nell'Acropoli, P. XLVI ; Marchesi, C., In difesa della scuola, P. LIII ; Malquori, G., Il Rettore, P. LVII ; Montesano, R., Nel giugno '18, P. LXIV ; Bologna, G., Nella guerra di liberazione, P. LXXI ; Russo, L., Breve storia di un'amicizia e di un carteggio, P. LXXV ; Pugliese Carratelli, G., Ricordo del maestro, P. LXXXIII ; Nota biografica ; Bibliografia ; Omodeo, A., Trentacinque anni di lavoro storico, P. CX.
Stability index for orbits with nonvanishing diffusion
Creators: name: Milstein, Grigori N.
Publisher: name: Weierstrass Institute
Year: 1997
Subjects: subject: stochastic stability
subject: Lyapunov exponent
subject: moment Lyapunov exponents
subject: stability index
subject: 60H10
subject: 93E15

description: The known concepts of Lyapunov exponent, moment Lyapunov exponents, and stability index for stationary points of stochastic systems are carried over for invariant orbits with nonvanishing diffusion. The obtained general results are applied to investigating stochastic stability and stabilization of orbits on the plane.
Profiling Cys 34 Adducts of Human Serum Albumin by Fixed-Step Selected Reaction Monitoring
Creators: name: Li, He
name: Lu, Sixin Samantha
name: Funk, William E.
name: Grigoryan, Hasmik
name: Rose, Sherri
name: Williams, Evan R.
name: Rappaport, Stephen M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: A method is described for profiling putative adducts (or other unknown covalent modifications) at the Cys34 locus of human serum albumin (HSA), which represents the preferred reaction site for small electrophilic species in human serum. By comparing profiles of putative HSA-Cys34 adducts across populations of interest it is theoretically possible to explore environmental causes of degenerative diseases and cancer caused by both exogenous and endogenous chemicals. We report a novel application of selected-reaction-monitoring (SRM) mass spectrometry, termed fixed-step SRM (FS-SRM), that allows detection of essentially all HSA-Cys34 modifications over a specified range of mass increases (added masses). After tryptic digestion, HSA-Cys34 adducts are contained in the third largest peptide (T3), which contains 21 amino acids and an average mass of 2433.87 Da. The FS-SRM method does not require that exact masses of T3 adducts be known in advance but rather uses a theoretical list of T3-adduct m/z values separated by a fixed increment of 1.5. In terms of added masses, each triply charged parent ion represents a bin of ±2.3 Da between 9.1 Da and 351.1 Da. Synthetic T3 adducts were used to optimize FS-SRM and to establish screening rules based upon selected b- and y-series fragment ions. An isotopically labeled T3 adduct is added to protein digests to facilitate quantification of putative adducts. We used FS-SRM to generate putative adduct profiles from six archived specimens of HSA that had been pooled by gender, race, and smoking status. An average of 66 putative adduct hits (out of a possible 77) were detected in these samples. Putative adducts covered a wide range of concentrations, were most abundant in the mass range below 100 Da, and were more abundant in smokers than in nonsmokers. With minor modifications, the FS-SRM methodology can be applied to other nucleophilic sites and proteins.
The Kepler Dichotomy among the M Dwarfs: Half of Systems Contain Five or More Coplanar Planets
Creators: name: Ballard, Sarah
name: Johnson, John Asher
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a statistical analysis of the Kepler M dwarf planet hosts, with a particular focus on the fractional number of systems hosting multiple transiting planets. We manufacture synthetic planetary systems within a range of planet multiplicity and mutual inclination for comparison to the Kepler yield. We recover the observed number of systems containing between 2 and 5 transiting planets if every M dwarf hosts 6.1+/-1.9 planets with typical mutual inclinations of 2.0 +4.0-2.0 degrees. This range includes the Solar System in its coplanarity and multiplicity. However, similar to studies of Kepler exoplanetary systems around more massive stars, we report that the number of singly-transiting planets found by Kepler is too high to be consistent with a single population of multi-planet systems: a finding that cannot be attributed to selection biases. To account for the excess singleton planetary systems we adopt a mixture model and find that 55 +23-12% of planetary systems are either single or contain multiple planets with large mutual inclinations. Thus, we find that the so-called "Kepler dichotomy" holds for planets orbiting M dwarfs as well as Sun-like stars. Additionally, we compare stellar properties of the hosts to single and multiple transiting planets. For the brightest subset of stars in our sample we find intriguing, yet marginally significant evidence that stars hosting multiply-transiting systems are rotating more quickly, are closer to the midplane of the Milky Way, and are comparatively metal poor. This preliminary finding warrants further investigation.
description: 12 pages, 9 figures. Submitted to ApJ
Impact Sheet to IRME 2017
Creators: name: Heine Barnett, Janet
name: Clark, Kathleen M.
name: Can, Cihan
Publisher: name: Brill Online
Year: 2022
Subjects: Education assessment and evaluation

description: Impact Sheet to Transforming Mathematics Instruction Via Primary Historical Sources: A Study of Influential Factors on Implementation of a Curricular Innovation at the Tertiary Level
Possible binary progenitors for the type Ib supernova iPTF13bvn
Creators: name: Eldridge, J. J.
name: Fraser, Morgan
name: Maund, Justyn R.
name: Smartt, Stephen J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Cao et al. (2013) reported a possible progenitor detection for the type Ib supernovae iPTF13bvn for the first time. We find that the progenitor is in fact brighter than the magnitudes previously reported by approximately 0.7 to 0.2 mag with a larger error in the bluer filters. We compare our new magnitudes to our large set of binary evolution models and find that many binary models with initial masses in the range of 10 to 20M(Sun) match this new photometry and other constraints suggested from analysing the supernova. In addition these lower mass stars retain more helium at the end of the model evolution indicating that they are likely to be observed as type Ib supernovae rather than their more massive, Wolf-Rayet counter parts. We are able to rule out typical Wolf-Rayet models as the progenitor because their ejecta masses are too high and they do not fit the observed SED unless they have a massive companion which is the observed source at the supernova location. Therefore only late-time observations of the location will truly confirm if the progenitor was a helium giant and not a Wolf-Rayet star.
description: 8 pages, 2 figures, Submitted to MNRAS, comment welcome
The critical radiation intensity for direct collapse black hole formation: dependence on the radiation spectral shape
Creators: name: Sugimura, Kazuyuki
name: Omukai, Kazuyuki
name: Inoue, Akio K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: It has been proposed that supermassive black holes (SMBHs) are originated from direct-collapse black holes (DCBHs) that are formed at z gtrsim 10 in the primordial gas in the case that H2 cooling is suppressed by strong external radiation. In this work, we study the critical specific intensity J^crit required for DCBH formation for various radiation spectral shapes by a series of one-zone calculations of a collapsing primordial- gas cloud. We calculate the critical specific intensity at the Lyman-Werner (LW) bands J^crit_LW,21 (in units of 10^-21 erg s^-1 Hz^-1 sr^-1 cm^-2) for realistic spectra of metal-poor galaxies. We find J^crit is not sensitive to the age or metallicity for the constant star formation galaxies with J^crit_LW,21 = 1300-1400, while J^crit decreases as galaxies become older or more metal-enriched for the instantaneous starburst galaxies. However, such dependence for the instantaneous starburst galaxies is weak for the young or extremely metal-poor galaxies: J^crit_LW,21 = 1000-1400 for the young galaxies and J^crit_LW,21 approx 1400 for the extremely metal-poor galaxies. The typical value of J^crit for the realistic spectra is higher than those expected in the literature, which affects the estimated DCBH number density n_DCBH. By extrapolating the result of Dijkstra, Ferrara and Mesinger, we obtain n_DCBH sim 10^-10 cMpc^-3 at z = 10, although there is still large uncertainty in this estimation.
description: 11 pages, 6 figures, submitted to MNRAS
Christin, Jean, Los adolescentes. Temas para retiros, forum-juveniles y convivências. Ed. Marova. Vol. de 229 ps. 142x194. Madrid 1968
Creators: name: Ferraz, Agostinho Moreira
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
Structurally Informative Tandem Mass Spectrometry of Highly Sulfated Natural and Chemoenzymatically Synthesized Heparin and Heparan Sulfate Glycosaminoglycans
Creators: name: Li, Lingyun
name: Liu, Jian
name: Xu, Yongmei
name: Linhardt, Robert J.
name: Amster, I. Jonathan
name: Kailemia, Muchena J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The highly sulfated glycosaminoglycan oligosaccharides derived from heparin and heparan sulfate have been a highly intractable class of molecules to analyze by tandem mass spectrometry. Under the many methods of ion activation, this class of molecules generally exhibits SO3 loss as the most significant fragmentation pathway, interfering with the assignment of the location of sulfo groups in glycosaminoglycan chains. We report here a method that stabilizes sulfo groups and facilitates the complete structural analysis of densely sulfated (two or more sulfo groups per disaccharide repeat unit) heparin and heparan sulfate oligomers. This is achieved by complete removal of all ionizable protons, either by charging during electrospray ionization or by Na+/H+ exchange. The addition of millimolar levels of NaOH to the sample solution facilitates the production of precursor ions that meet this criterion. This approach is found to work for a variety of heparin sulfate oligosaccharides derived from natural sources or produced by chemoenzymatic synthesis, with up to 12 saccharide subunits and up to 11 sulfo groups.
High visibility two photon interference of frequency time entangled photons generated in a quasi phase matched AlGaAs waveguide
Creators: name: Sarrafi, Peyman
name: Zhu, Eric Y.
name: Holmes, Barry M.
name: Hutchings, David C.
name: Aitchison, Stewart
name: Qian, Li
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We demonstrate experimentally the frequency time entanglement of photon pairs produced in a CW pumped quasi phased matched AlGaAs superlattice waveguide. A visibility of 96.0+-0.7% without background subtraction has been achieved, which corresponds the violation of Bell inequality by 52 standard deviations.
National Register of Historic Places Historic Context and Evaluation for Kirtland Air Force Base, Albuquerque, New Mexico Research Data: Air Force Weapons Laboratory (AFWL) Histories and Construction Engineering Research Laboratory (CERL)
Creators: name: Van Citters, Karen
Publisher: name: Van Citters Historic Preservation
Year: 2003
Subjects: subject: Bernalillo (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3646/bernalillo-county
subject: Albuquerque, New Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/84765/albuquerque-new-mexico
subject: Kirtland Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/17943/kirtland-air-force-base
subject: Cold War Era
valueUri: https://core.tdar.org/browse/temporal-keyword/5551/cold-war-era
subject: Historic
valueUri: https://core.tdar.org/browse/temporal-keyword/5728/historic
subject: World War II
valueUri: https://core.tdar.org/browse/temporal-keyword/3992/world-war-ii
subject: Cold War
valueUri: https://core.tdar.org/browse/temporal-keyword/7288/cold-war
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: AFWL
valueUri: https://core.tdar.org/browse/site-name/129966/afwl
subject: Air Force Weapons Laboratory
valueUri: https://core.tdar.org/browse/site-name/129965/air-force-weapons-laboratory
subject: CERL
valueUri: https://core.tdar.org/browse/site-name/129968/cerl
subject: Construction Engineering Research Laboratory
valueUri: https://core.tdar.org/browse/site-name/129967/construction-engineering-research-laboratory
subject: Historic Governmental Structure
valueUri: https://core.tdar.org/browse/site-type/320/historic-governmental-structure
subject: Military Structure
valueUri: https://core.tdar.org/browse/site-type/322/military-structure
subject: Historic Context
valueUri: https://core.tdar.org/browse/other-keyword/42191/historic-context
subject: NRHP
valueUri: https://core.tdar.org/browse/other-keyword/9857/nrhp
subject: National Register of Historic Places
valueUri: https://core.tdar.org/browse/other-keyword/1572/national-register-of-historic-places
subject: Architectural Documentation
valueUri: https://core.tdar.org/browse/investigation-type/16/architectural-documentation
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: Data collected for the 2003 National Register of Historic Places Historic Context and Evaluation for Kirtland Air Force Base in Albuquerque, New Mexico. Documents include old reports and records.
Additional file 1 of Efficacy and safety of botulinum toxin-A in writer’s cramp: a systematic review, meta-analysis, and meta-regression
Creators: name: Patil, Anant
name: Shaikh, Summaiya Zareen
name: Karajgi, Asmita
name: Ali, Mohammed Usman
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Studies assessed using the NIH Quality Assessment Tool for Observational cohort and Cross-sectional studies. Table S2. Meta-Analysis and Meta-Regression for WCRS scores in WC
A Computational Framework for Heparan Sulfate Sequencing Using High-resolution Tandem Mass Spectra
Creators: name: Xu, Yongmei
name: Huang, Yu
name: Boons, Geert-Jan
name: Hu, Han
name: Liu, Jian
name: Zong, Chengli
name: Zaia, Joseph
name: Mao, Yang
name: Lin, Cheng
name: Yu, Xiang
name: Xia, Yu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Heparan sulfate (HS) is a linear polysaccharide expressed on cell surfaces, in extracellular matrices and cellular granules in metazoan cells. Through non-covalent binding to growth factors, morphogens, chemokines, and other protein families, HS is involved in all multicellular physiological activities. Its biological activities depend on the fine structures of its protein-binding domains, the determination of which remains a daunting task. Methods have advanced to the point that mass spectra with information-rich product ions may be produced on purified HS saccharides. However, the interpretation of these complex product ion patterns has emerged as the bottleneck to the dissemination of these HS sequencing methods. To solve this problem, we designed HS-SEQ, the first comprehensive algorithm for HS de novo sequencing using high-resolution tandem mass spectra. We tested HS-SEQ using negative electron transfer dissociation (NETD) tandem mass spectra generated from a set of pure synthetic saccharide standards with diverse sulfation patterns. The results showed that HS-SEQ rapidly and accurately determined the correct HS structures from large candidate pools.
Investigation graph isomorphism problem via entanglement entropy in strongly regular graphs
Creators: name: Jafarizadeh, M. A.
name: Eghbalifam, F.
name: Nami, S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the quantum networks that their nodes are considered as quantum harmonic oscillators. The entanglement of the ground state can be used to quantify the amount of information one part of a network shares with the other part of the system. The networks which we studied in this paper, are called strongly regular graphs (SRG). These kinds of graphs have some special properties like they have three strata in the stratification basis. The Schur complement method is used to calculate the Schmidt number and entanglement entropy between two parts of graph. We could obtain analytically, all blocks of adjacency matrix in several important kinds of strongly regular graphs. Also the entanglement entropy in the large coupling limit is considered in these graphs and the relationship between Entanglement entropy and the ratio of size of boundary to size of the system is found. Then, area-law is studied to show that there are no entanglement entropy for the highest size of system. Then, the graph isomorphism problem is considered in SRGs by using the elements of blocks of adjacency matrices. Two SRGs with the same parameters: $(η,κ,λ,ν)$ are isomorphic if they can be made identical by relabeling their vertices. So the adjacency matrices of two isomorphic SRGs become identical by replacing of rows and columns. The nonisomirph SRGs could be distinguished by using the elements of blocks of adja- cency matrices in the stratification basis, numerically.
description: 37 pages. arXiv admin note: text overlap with arXiv:1206.2999, arXiv:1007.3739 by other authors
title: Prüfbericht G 2194 : Radialgebläse Turbine 456 ; Anerkannt für die Verwendung mit Spritz– und Sprühgeräten im Obst– und Weinbau
Creators: name: JKI-Institut Für Anwendungstechnik Im Pflanzenschutz
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2021
Subjects: subject: 630

description: Geräteprüfberichte des JKI, p. 1
Cita-Malard, Suzane, Les femmes dans L’Église à la lumière de Vatican II. Ed. Mame. Vol. de 296 ps. 138x215. Tours 1968
Creators: name: Ferraz, Agostinho Moreira
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
N6E4
Creators: name: Alyssah Clavien
Year: 2023
Subjects: subject: Mesoamerica
valueUri: https://core.tdar.org/browse/geographic-keyword/61/mesoamerica
subject: Basin of Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/3/basin-of-mexico
subject: Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/134/mexico
subject: Mexico (State / Territory)
valueUri: https://core.tdar.org/browse/geographic-keyword/326/mexico-state-territory
subject: United Mexican States (Country)
valueUri: https://core.tdar.org/browse/geographic-keyword/438/united-mexican-states-country
subject: Central Mexico, Teotihuacan Valley
valueUri: https://core.tdar.org/browse/geographic-keyword/7/central-mexico-teotihuacan-valley
subject: Central Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/135/central-mexico
subject: Teotihuacan Valley
valueUri: https://core.tdar.org/browse/geographic-keyword/154/teotihuacan-valley
subject: Teotihuacan
valueUri: https://core.tdar.org/browse/geographic-keyword/202/teotihuacan
subject: Valley of Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/44/valley-of-mexico
subject: Classic Period
valueUri: https://core.tdar.org/browse/temporal-keyword/125/classic-period
subject: Terminal Formative
valueUri: https://core.tdar.org/browse/temporal-keyword/67/terminal-formative
subject: Teotihuacan Period
valueUri: https://core.tdar.org/browse/temporal-keyword/7765/teotihuacan-period
subject: Early Classic
valueUri: https://core.tdar.org/browse/temporal-keyword/5560/early-classic
subject: Teotihuacan
valueUri: https://core.tdar.org/browse/culture-keyword/7527/teotihuacan
subject: Teotihuacano
valueUri: https://core.tdar.org/browse/culture-keyword/9224/teotihuacano
subject: Teotihuacan
valueUri: https://core.tdar.org/browse/site-name/92/teotihuacan
subject: Town / City
valueUri: https://core.tdar.org/browse/site-type/255/town-city
subject: Domestic Structure or Architectural Complex
valueUri: https://core.tdar.org/browse/site-type/251/domestic-structure-or-architectural-complex
subject: Settlements
valueUri: https://core.tdar.org/browse/site-type/252/settlements
subject: Systematic Survey
valueUri: https://core.tdar.org/browse/investigation-type/12/systematic-survey

description: Site Survey Form Scan for Square N6E4.
Additional file 9 of Adiposity and mortality among intensive care patients with COVID-19 and non-COVID-19 respiratory conditions: a cross-context comparison study in the UK
Creators: name: Bell, Joshua A.
name: Carslake, David
name: Hughes, Amanda
name: Tilling, Kate
name: Dodd, James W.
name: Doidge, James C.
name: Harrison, David A.
name: Rowan, Kathryn M.
name: Davey Smith, George
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 9: Figure S9 Respiratory support and BMI reporting profiles of ICU patients with COVID-19 (1 March 2020 to 31 July 2021) and non-COVID-19 respiratory conditions (1 Feb 2018 to 31 Aug 2019), by geographical region.
Effects of dust feedback on vortices in protoplanetary disks
Creators: name: Fu, Wen
name: Li, Hui
name: Lubow, Stephen
name: Li, Shengtai
name: Liang, Edison
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We carried out two-dimensional high-resolution simulations to study the effect of dust feedback on the evolution of vortices induced by massive planets in protoplanetary disks. Various initial dust to gas disk surface density ratios ($0.001$ -- $0.01$) and dust particle sizes (Stokes number $4\times10^{-4}$ -- $0.16$) are considered. We found that while dust particles migrate inwards, vortices are very effective in collecting them. When dust density becomes comparable to gas density within the vortex, a dynamical instability is excited and it alters the coherent vorticity pattern and destroys the vortex. This dust feedback effect is stronger with higher initial dust/gas density ratio and larger dust grain. Consequently, we found that the disk vortex lifetime can be reduced up to a factor of 10. We discuss the implications of our findings on the survivability of vortices in protoplanetary disks and planet formation.
description: Accepted for publication in ApJ Letter
A PWWP Domain-Containing Protein Targets the NuA3 Acetyltransferase Complex via Histone H3 Lysine 36 trimethylation to Coordinate Transcriptional Elongation at Coding Regions
Creators: name: McDaniel, Stephen L.
name: Byrum, Stephanie D.
name: Dancy, Blair C. R.
name: Cades, Jessica A.
name: Strahl, Brian D.
name: Gilbert, Tonya M.
name: Tackett, Alan J.
name: Taverna, Sean D.
name: Wade, Herschel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Post-translational modifications of histones, such as acetylation and methylation, are differentially positioned in chromatin with respect to gene organization. For example, although histone H3 is often trimethylated on lysine 4 (H3K4me3) and acetylated on lysine 14 (H3K14ac) at active promoter regions, histone H3 lysine 36 trimethylation (H3K36me3) occurs throughout the open reading frames of transcriptionally active genes. The conserved yeast histone acetyltransferase complex, NuA3, specifically binds H3K4me3 through a plant homeodomain (PHD) finger in the Yng1 subunit, and subsequently catalyzes the acetylation of H3K14 through the histone acetyltransferase domain of Sas3, leading to transcription initiation at a subset of genes. We previously found that Ylr455w (Pdp3), an uncharacterized proline-tryptophan-tryptophan-proline (PWWP) domain-containing protein, copurifies with stable members of NuA3. Here, we employ mass-spectrometric analysis of affinity purified Pdp3, biophysical binding assays, and genetic analyses to classify NuA3 into two functionally distinct forms: NuA3a and NuA3b. Although NuA3a uses the PHD finger of Yng1 to interact with H3K4me3 at the 5′-end of open reading frames, NuA3b contains the unique member, Pdp3, which regulates an interaction between NuA3b and H3K36me3 at the transcribed regions of genes through its PWWP domain. We find that deletion of PDP3 decreases NuA3-directed transcription and results in growth defects when combined with transcription elongation mutants, suggesting NuA3b acts as a positive elongation factor. Finally, we determine that NuA3a, but not NuA3b, is synthetically lethal in combination with a deletion of the histone acetyltransferase GCN5, indicating NuA3b has a specialized role at coding regions that is independent of Gcn5 activity. Collectively, these studies define a new form of the NuA3 complex that associates with H3K36me3 to effect transcriptional elongation. MS data are available via ProteomeXchange with identifier PXD001156.
title: ENTAM - Prüfbericht D 2264 : Gerätetyp: Selbstfahrendes Feldspritzgerät, Fabrikat: Agrifac, Gerätetyp: Condor 5 [barrierefrei]
Creators: name: JKI-Institut Für Anwendungstechnik Im Pflanzenschutz
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2021
Subjects: subject: 600

description: Geräteprüfberichte des JKI, p. 1
Spectral signatures of high-symmetry quantum dots and effects of symmetry breaking
Creators: name: Karlsson, K. Fredrik
name: Oberli, Daniel Y.
name: Dupertuis, Marc-André
name: Troncale, Valentina
name: Byszewski, Marcin
name: Pelucchi, Emanuele
name: Rudra, Alok
name: Holtz, Per Olof
name: Kapon, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A sequence of photoluminescence spectroscopy based methods are used to rigorously identify and study all the main spectral features (more than thirty emission lines) of site controlled InGaAs/AlGaAs quantum dots (QDs) grown along [111]B in inverted tetrahedral pyramids. The studied QDs reveal signatures of one confined electron level, one heavy-hole-like level and one light-hole-like level. The various heavy-light-hole hybrid exciton complexes formed in these QDs are studied by polarization resolved spectroscopy, excitation power dependence, crystal temperature dependence and temporal single photon correlation measurements. The presented approach, which only requires a minimal theoretical input, enables strict spectral identification of the fine structure patterns including weak and spectrally overlapping emission lines. Furthermore, it allows the involved electron-hole and hole-hole exchange interaction energies to be deduced from measurements. Intricate fine structure patterns are qualitatively understood by group theory and shown to be very sensitive to the exact symmetry of the QD. Emission patterns influenced by hole-hole exchange interactions are found to be particularly useful for identifying QDs with high $C_{3v}$ symmetry and for probing symmetry breaking.
description: 20 pages, 22 figures
Vários, L’Aggiornamento Teologico pastorale dei Sacerdoti, Atti del II Convegno di Teologia pastorale organizzato dalla Rivista «Studi cattolici», Castello di Urio, 23-26 Luglio 1967. Ed. Ares. V Vol. de 96 ps. 180x215. Milano 1968
Creators: name: Ferraz, Agostinho Moreira
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
Additional file 1 of Using human factors principles to redesign a 3D lab workflow during the COVID-19 pandemic
Creators: name: Larsen, Ethan P.
name: Silvestro, Elizabeth
name: Ferro, Daria F.
name: Chinwalla, Asif
name: Oppenheimer, Natalie
name: Rogers, Sarah
name: Sze, Raymond W.
name: Winston, Flaura K.
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1. Project Submission Form.
An Unbiased Proteomic Screen Reveals Caspase Cleavage Is Positively and Negatively Regulated by Substrate Phosphorylation
Creators: name: Smalley, David M.
name: Li, Shawn S. C.
name: Graves, Lee M.
name: Zukowski, Stephanie A.
name: Lajoie, Gilles A.
name: Knight, James D. R.
name: Turowec, Jacob P.
name: Litchfield, David W.
name: Johnson, Gary L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Post-translational modifications of proteins regulate diverse cellular functions, with mounting evidence suggesting that hierarchical cross-talk between distinct modifications may fine-tune cellular responses. For example, in apoptosis, caspases promote cell death via cleavage of key structural and enzymatic proteins that in some instances is inhibited by phosphorylation near the scissile bond. In this study, we systematically investigated how protein phosphorylation affects susceptibility to caspase cleavage using an N-terminomic strategy, namely, a modified terminal amino isotopic labeling of substrates (TAILS) workflow, to identify proteins for which caspase-catalyzed cleavage is modulated by phosphatase treatment. We validated the effects of phosphorylation on three of the identified proteins and found that Yap1 and Golgin-160 exhibit decreased cleavage when phosphorylated, whereas cleavage of MST3 was promoted by phosphorylation. Furthermore, using synthetic peptides we systematically examined the influence of phosphoserine throughout the entirety of caspase-3, -7, and -8 recognition motifs and observed a general inhibitory effect of phosphorylation even at residues considered outside the classical consensus motif. Overall, our work demonstrates a role for phosphorylation in controlling caspase-mediated cleavage and shows that N-terminomic strategies can be tailored to study cross-talk between phosphorylation and proteolysis.
Assessment of Damages to Sites AR 03-03-05-221 and AR 03-03-05-218 on Withdrawn Forest Service Lands on Kirtland Air Force Base Addendum to Report AR 90-03-052A
Creators: name: Johnson, Michael
Year: 1990
Subjects: subject: Bernalillo (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3646/bernalillo-county
subject: Albuquerque, New Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/84765/albuquerque-new-mexico
subject: Kirtland Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/17943/kirtland-air-force-base
subject: Historic
valueUri: https://core.tdar.org/browse/temporal-keyword/5728/historic
subject: Prehistoric
valueUri: https://core.tdar.org/browse/temporal-keyword/53/prehistoric
subject: LA 77249
valueUri: https://core.tdar.org/browse/site-name/130352/la-77249
subject: LA 77687
valueUri: https://core.tdar.org/browse/site-name/130509/la-77687
subject: AR 03-03-05-218
valueUri: https://core.tdar.org/browse/site-name/131261/ar-03-03-05-218
subject: NM O:3:1:18
valueUri: https://core.tdar.org/browse/site-name/131262/nm-o3118
subject: AR 03-03-05-221
valueUri: https://core.tdar.org/browse/site-name/131260/ar-03-03-05-221
subject: NM 0:3:1:18
valueUri: https://core.tdar.org/browse/site-name/130442/nm-03118
subject: Trash Midden
valueUri: https://core.tdar.org/browse/site-type/351/trash-midden
subject: Rock Alignment
valueUri: https://core.tdar.org/browse/site-type/360/rock-alignment
subject: Coyote Test Field
valueUri: https://core.tdar.org/browse/site-type/4713/coyote-test-field
subject: Masonry House
valueUri: https://core.tdar.org/browse/site-type/1226/masonry-house
subject: Cobble
valueUri: https://core.tdar.org/browse/material-type/1165/cobble
subject: Site Restoration
valueUri: https://core.tdar.org/browse/other-keyword/123821/site-restoration
subject: Damage Assessment
valueUri: https://core.tdar.org/browse/other-keyword/67508/damage-assessment
subject: Ground Disturbance Monitoring
valueUri: https://core.tdar.org/browse/investigation-type/20/ground-disturbance-monitoring
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: An addendum to the report AR 90-03-052A assessing the damage to sites AR 03-03-05-221 and AR 03-03-05-218.
Girardi, Jules e Six. J. F., (dir.), L’Athéisme datis la vie et ta culture contemporaines. Vol. I 1-2. Ed. Desclée. Vol. de 503 e 488 ps. 155x225. Paris 1968
Creators: name: Correia, Francisco Carvalho
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
The Global Phosphoproteome of Chlamydomonas reinhardtii Reveals Complex Organellar Phosphorylation in the Flagella and Thylakoid Membrane
Creators: name: Juergens, Matthew
name: Hicks, Leslie M.
name: Gau, Brian
name: Wang, Hongxia
name: Li, Ping
name: Slade, William O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Chlamydomonas reinhardtii is the most intensively-studied and well-developed model for investigation of a wide-range of microalgal processes ranging from basic development through understanding triacylglycerol production. Although proteomic technologies permit interrogation of these processes at the protein level and efforts to date indicate phosphorylation-based regulation of proteins in C. reinhardtii is essential for its underlying biology, characterization of the C. reinhardtii phosphoproteome has been limited. Herein, we report the richest exploration of the C. reinhardtii proteome to date. Complementary enrichment strategies were used to detect 4588 phosphoproteins distributed among every cellular component in C. reinhardtii. Additionally, we report 18,160 unique phosphopeptides at <1% false discovery rate, which comprise 15,862 unique phosphosites - 98% of which are novel. Given that an estimated 30% of proteins in a eukaryotic cell are subject to phosphorylation, we report the majority of the phosphoproteome (23%) of C. reinhardtii. Proteins in key biological pathways were phosphorylated, including photosynthesis, pigment production, carbon assimilation, glycolysis, and protein and carbohydrate metabolism, and it is noteworthy that hyperphosphorylation was observed in flagellar proteins. This rich data set is available via ProteomeXchange (ID: PXD000783) and will significantly enhance understanding of a range of regulatory mechanisms controlling a variety of cellular process and will serve as a critical resource for the microalgal community.
The Masses and Spins of Neutron Stars and Stellar-Mass Black Holes
Creators: name: Miller, M. Coleman
name: Miller, Jon M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Stellar-mass black holes and neutron stars represent extremes in gravity, density, and magnetic fields. They therefore serve as key objects in the study of multiple frontiers of physics. In addition, their origin (mainly in core-collapse supernovae) and evolution (via accretion or, for neutron stars, magnetic spindown and reconfiguration) touch upon multiple open issues in astrophysics. In this review, we discuss current mass and spin measurements and their reliability for neutron stars and stellar-mass black holes, as well as the overall importance of spins and masses for compact object astrophysics. Current masses are obtained primarily through electromagnetic observations of binaries, although future microlensing observations promise to enhance our understanding substantially. The spins of neutron stars are straightforward to measure for pulsars, but the birth spins of neutron stars are more difficult to determine. In contrast, even the current spins of stellar-mass black holes are challenging to measure. As we discuss, major inroads have been made in black hole spin estimates via analysis of iron lines and continuum emission, with reasonable agreement when both types of estimate are possible for individual objects, and future X-ray polarization measurements may provide additional independent information. We conclude by exploring the exciting prospects for mass and spin measurements from future gravitational wave detections, which are expected to revolutionize our understanding of strong gravity and compact objects.
description: 97 pages, 5 figures, solicited review for Physics Reports
title: ENTAM - Test Report D 2264 : Self propelled Field Crop Sprayer, Agrifac, Condor 5 [barrierefrei]
Creators: name: JKI-Institut Für Anwendungstechnik Im Pflanzenschutz
Publisher: name: Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
Year: 2021
Subjects: subject: 600

description: Geräteprüfberichte des JKI, p. 1
Additional file 5 of Exploring fine-scale urban landscapes using satellite data to predict the distribution of Aedes mosquito breeding sites
Creators: name: Teillet, Claire
name: Devillers, Rodolphe
name: Tran, Annelise
name: Catry, Thibault
name: Marti, Renaud
name: Dessay, Nadine
name: Rwagitinywa, Joseph
name: Restrepo, Johana
name: Roux, Emmanuel
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 5
Zeliauskas, Josephus, De excommunicatione vitiata apud. glossatores (1140-1350. Ed. Pas Verlag Zurich. Vol. de XLIII+377 ps. 170x235. Zurich 1967
Creators: name: Gigante, José António Martins
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer
Creators: name: Park, Ben Ho
name: Morrison, Meghan M.
name: Cook, Rebecca S.
name: Brantley-Sieders, Dana M.
name: Liebler, Daniel C.
name: O'Shaughnessy, Joyce A.
name: Wang, Kai
name: Zimmerman, Lisa J.
name: Dave, Bhuvanesh
name: Stephens, Philip J.
name: Bhola, Neil E.
name: Stricker, Thomas
name: Horiates, Marina
name: Chang, Jenny C.
name: Levin, Maren
name: Patel, Premal
name: Palma, Norma A.
name: Silva, Grace O.
name: Perou, Charles M.
name: Whitwell, Corbin A.
name: Formisano, Luigi
name: Gatza, Michael L.
name: Young, Christian D.
name: Weaver, Alissa M.
name: Hoshino, Daisuke
name: Arteaga, Carlos L.
name: Moore, Preston D.
name: Hanker, Ariella B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Mutations in PIK3CA, the gene encoding the p110α catalytic subunit of phosphoinositide 3-kinase (PI3K) have been shown to transform human mammary epithelial cells (MECs). These mutations are present in all breast cancer subtypes, including basal-like breast cancer (BLBC). Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), we identified 72 protein expression changes in human basal-like MECs with knock-in E545K or H1047R PIK3CA mutations versus isogenic MECs with wild-type PIK3CA. Several of these were secreted proteins, cell surface receptors or ECM interacting molecules and were required for growth of PIK3CA mutant cells as well as adjacent cells with wild-type PIK3CA. The proteins identified by MS were enriched among human BLBC cell lines and pointed to a PI3K-dependent amphiregulin/EGFR/ERK signaling axis that is activated in BLBC. Proteins induced by PIK3CA mutations correlated with EGFR signaling and reduced relapse-free survival in BLBC. Treatment with EGFR inhibitors reduced growth of PIK3CA mutant BLBC cell lines and murine mammary tumors driven by a PIK3CA mutant transgene, all together suggesting that PIK3CA mutations promote tumor growth in part by inducing protein changes that activate EGFR.