cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination
Creators: name: Peschl, Patrick
name: Schanda, Kathrin
name: Zeka, Bleranda
name: Given, Katherine
name: Boehm, Denise
name: Ruprecht, Klemens
name: Saiz, Albert [U. A.]
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Myelin oligodendrocyte glycoprotein
subject: MOG
subject: Antibodies
subject: Organotypic slice culture
subject: EAE
subject: Neuromyelitis optica spectrum disorders
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Antibodies to the myelin oligodendrocyte glycoprotein (MOG) are associated with a subset of inflammatory demyelinating diseases of the central nervous system such as acute disseminated encephalomyelitis and neuromyelitis optica spectrum disorders. However, whether human MOG antibodies are pathogenic or an epiphenomenon is still not completely clear. Although MOG is highly conserved within mammals, previous findings showed that not all human MOG antibodies bind to rodent MOG. We therefore hypothesized that human MOG antibody-mediated pathology in animal models may only be evident using species-specific MOG antibodies. Methods We screened 80 human MOG antibody- positive samples for their reactivity to mouse and rat MOG using either a live cell-based assay or immunohistochemistry on murine, rat, and human brain tissue. Selected samples reactive to either human MOG or rodent MOG were subsequently tested for their ability to induce complement-mediated damage in murine organotypic brain slices or enhance demyelination in an experimental autoimmune encephalitis (EAE) model in Lewis rats. The MOG monoclonal antibody 8-18-C5 was used as a positive control. Results Overall, we found that only a subset of human MOG antibodies are reactive to mouse (48/80, 60%) or rat (14/80, 18%) MOG. Purified serum antibodies from 10 human MOG antibody- positive patients (8/10 reactive to mouse MOG, 6/10 reactive to rat MOG), 3 human MOG-negative patients, and 3 healthy controls were tested on murine organotypic brain slices. Purified IgG from one patient with high titers of anti-human, mouse, and rat MOG antibodies and robust binding to myelin tissue produced significant, complement-mediated myelin loss in organotypic brain slices, but not in the EAE model. Monoclonal 8-18-C5 MOG antibody caused complement-mediated demyelination in both the organotypic brain slice model and in EAE. Conclusion This study shows that a subset of human MOG antibodies can induce complement-dependent pathogenic effects in a murine ex vivo animal model. Moreover, a high titer of species-specific MOG antibodies may be critical for demyelinating effects in mouse and rat animal models. Therefore, both the reactivity and titer of human MOG antibodies must be considered for future pathogenicity studies.
Tubulin isoforms: Involvement in the formation of stable microtubule arrays during neural differentiation.
Creators: name: Falconer, Marcia M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Biology, Cell.

description: In this thesis, commitment is defined as the events that constrain a cell (and its progeny) to follow a particular developmental path, while differentiation is narrowly considered to involve events that result in attainment of a specific cell shape and does not consider functional or other characteristics. Therefore the P19 culture system was used to investigate the involvement of alpha and beta tubulin isoforms in formation of the stable microtubule (MT) array during neural differentiation. Two posttranslational modifications of alpha tubulin, acetylation and detryosination, are associated with stable MT populations including those of neural processes. Uncommitted embryonal carcinoma (EC) cells have minimal arrays of acetylated and detyrosinated MTs. Following neural induction with retinoic acid (RA), indirect immunofluorescence microscopy shows that the first MT modifications occur during commitment, before any morphological change is observed. RA-induced cells initially polymerize a temporarily enlarged population of MTs. Included in this population is a new array of acetylated MTs arranged in a bundle of parallel MTs. This bundle is colchicine stable and only MT-associated protein (MAP) 1B is detected in association with this bundle. In cells which proceed to differentiate directly after commitment, this bundle apparently extends to form a neural process. MAP2C is first detected at about the time of neurite extension but is not limited to dendritic processes. During a brief period early in differentiation, indirect immunofluorescence staining shows the colocalization of colchicine stable acetylated MTs, vimentin and MAP2C. This thesis shows that acetylated MTs, MAP2 and vimentin intermediate filaments are arranged in an interdependent cytoskeletal array. This array may serve to stabilize processes in neural stem cells thereby allowing the stem cell to receive signals which influence the final decision to differentiate into neurons or glia. Finally, the involvement of beta tubulin isotypes in formation of the stable MT array during neural differentiation in P19 cells is analyzed by indirect immunofluorescence staining and by immunoblotting. (Abstract shortened by UMI.)
La relation entre le niveau d'éducation des adultes d'un groupe ethnique et la réussite académique au secondaire: Étude de cas des Luso-canadiens, des Indo-canadiens et des Canado-jamaïcains à Toronto en 2001
Creators: name: Jonathas, Johanne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Education, Multilingual.
subject: Sociology, Ethnic and Racial Studies.

description: Cette thèse est une étude exploratoire qui porte sur le lien entre le niveau d'éducation moyen des adultes d'un groupe ethnique et la réussite scolaire au secondaire des jeunes de ce groupe. Afin de mieux comprendre la question, une comparaison interethnique est effectuée entre les Luso-canadiens, les Canado-jamaïcains et les Indo-canadiens à Toronto en 2001. La théorie de la reproduction des classes de Bourdieu est le cadre théorique choisi. Afin d'effectuer des comparaisons, des descriptions de chaque groupe ethnique et des données statistiques sont utilisées. À la lumière des analyses effectuées pour chaque groupe ethnique, il semble exister un lien entre le niveau d'éducation général des adultes d'un groupe ethnique et la réussite académique de ces jeunes. L'étude étant exploratoire, les conclusions ne permettent pas de comprendre la question complètement. Néanmoins, des études empiriques dans ce domaine seraient utiles pour mieux comprendre la réussite scolaire des enfants issus de l'immigration et ainsi favoriser la mobilité sociale.
title: Hydrofluorocarbon emission reduction: a crucial contribution to climate protection
title: Hydrofluorocarbon emission reduction: a crucial contribution to climate protection
titleType: AlternativeTitle
Creators: name: Elsner, Cornelia
name: Graaf, Daniel De
name: Graaf, Daniel De
name: Hoffmann, Gabriele
name: Martens, Kerstin
name: Plehn, Wolfgang
name: Thalheim, Diana
Publisher: name: Umweltbundesamt
Year: 2021
Subjects: subject: H-FCKW
subject: HFKW
subject: Klima | Energie
subject: Climate | Energy

description: Hydrofluorocarbons (HFCs) are the dominant fraction of fluorinated greenhouse gases, also known as F-gases. HFC emissions in the European Union (EU) amounted to 112 million tonnes CO2 equivalent (Mt CO2eq.) in 2018. This amounts to 2,2% of the EU's total greenhouse gas emissions. Main sources of HFC emissions are refrigeration and air conditioning plants and appliances. Following a proposal by the EU Commission, EU member states and the EU parliament just recently agreed to increase the 2030 target from 40% to 55% reduction of greenhouse gas emissions compared to the 1990 level. This considerable step-up of climate ambition by more than a third needs to be reflected also in the revision process of the F-gas Regulation, regardless of the achievements already made to curb F-gas emissions. On the occasion of the F-gas Regulation revision, the German Environment Agency proposes the acceleration of the phase-down scenario, resulting in larger reduction steps from 2024 on and a final level of 10% of the baseline by 2030 compared to 21% according to the current schedule. Source: www.umweltbundesamt.de
description: Hydrofluorocarbons (HFCs) are the dominant fraction of fluorinated greenhouse gases, also known as F-gases. HFC emissions in the European Union (EU) amounted to 112 million tonnes ⁠CO2⁠ equivalent (Mt CO2eq.) in 2018. This amounts to 2,2% of the EU’s total greenhouse gas emissions. Main sources of HFC emissions are refrigeration and air conditioning plants and appliances.Following a proposal by the EU Commission, EU member states and the EU parliament just recently agreed to increase the 2030 target from 40% to 55% reduction of greenhouse gas emissions compared to the 1990 level. This considerable step-up of climate ambition by more than a third needs to be reflected also in the revision process of the F-gas Regulation, regardless of the achievements already made to curb F-gas emissions.On the occasion of the F-gas Regulation revision, the German Environment Agency proposes the acceleration of the phase-down scenario, resulting in larger reduction steps from 2024 on and a final level of 10% of the baseline by 2030 compared to 21% according to the current schedule.
WISE x SuperCOSMOS Photometric Redshift Catalog: 20 million galaxies over 3/pi Steradians
Creators: name: Bilicki, Maciej
name: Peacock, John A.
name: Jarrett, Thomas H.
name: Cluver, Michelle
name: Maddox, Natasha
name: Brown, Michael J. I.
name: Taylor, Edward
name: Hambly, Nigel C.
name: Solarz, Aleksandra
name: Holwerda, Benne W.
name: Baldry, Ivan
name: Loveday, Jon
name: Moffett, Amanda
name: Hopkins, Andrew M.
name: Driver, Simon P.
name: Alpaslan, Mehmet
name: Bland-Hawthorn, Joss
Publisher: name: Swinburne
Year: 2024

description: We cross-match the two currently largest all-sky photometric catalogs-mid-infrared Wide-field Infrared Survey Explorer and SuperCOSMOS scans of UKST/POSS-II photographic plates-to obtain a new galaxy sample that covers 3π steradians. In order to characterize and purify the extragalactic data set, we use external GAMA and Sloan Digital Sky Survey spectroscopic information to define quasar and star loci in multicolor space, aiding the removal of contamination from our extended source catalog. After appropriate data cleaning, we obtain a deep wide-angle galaxy sample that is approximately 95% pure and 90% complete at high Galactic latitudes. The catalog contains close to 20 million galaxies over almost 70% of the sky, outside the Zone of Avoidance and other confused regions, with a mean surface density of more than 650 sources per square degree. Using multiwavelength information from two optical and two mid-IR photometric bands, we derive photometric redshifts for all the galaxies in the catalog, using the ANNz framework trained on the final GAMA-II spectroscopic data. Our sample has a median redshift of {z}{med}=0.2, with a broad {dN}/{dz} reaching up to z > 0.4. The photometric redshifts have a mean bias of | δ z| ˜ {10}-3, a normalized scatter of σ z = 0.033, and less than 3% outliers beyond 3σ z . Comparison with external data sets shows no significant variation of photo-z quality with sky position. Together with the overall statistics, we also provide a more detailed analysis of photometric redshift accuracy as a function of magnitudes and colors. The final catalog is appropriate for "all-sky" three-dimensional (3D) cosmology to unprecedented depths, in particular through cross-correlations with other large-area surveys. It should also be useful for source preselection and identification in forthcoming surveys, such as TAIPAN or WALLABY.
Medications that reduce emergency hospital admissions: an overview of systematic reviews and prioritisation of treatments
Creators: name: Bobrovitz, Niklas
name: Heneghan, Carl
name: Onakpoya, Igho
name: Fletcher, Benjamin
name: Collins, Dylan
name: Tompson, Alice
name: Lee, Joseph
name: Nunan, David
name: Fisher, Rebecca
name: Scott, Brittney
name: O’Sullivan, Jack
name: Van Hecke, Oliver
name: Nicholson, Brian D
name: Stevens, Sarah
name: Roberts, Nia
name: Mahtani, Kamal R
Publisher: name: BioMed Central
Year: 2018

description: Background: Rates of emergency hospitalisations are increasing in many countries, leading to disruption in the quality of care and increases in cost. Therefore, identifying strategies to reduce emergency admission rates is a key priority. There have been large-scale evidence reviews to address this issue; however, there have been no reviews of medication therapies, which have the potential to reduce the use of emergency health-care services. The objectives of this study were to review systematically the evidence to identify medications that affect emergency hospital admissions and prioritise therapies for quality measurement and improvement. Methods: This was a systematic review of systematic reviews. We searched MEDLINE, PubMed, the Cochrane Database of Systematic Reviews & Database of Abstracts of Reviews of Effects, Google Scholar and the websites of ten major funding agencies and health charities, using broad search criteria. We included systematic reviews of randomised controlled trials that examined the effect of any medication on emergency hospital admissions among adults. We assessed the quality of reviews using AMSTAR. To prioritise therapies, we assessed the quality of trial evidence underpinning meta-analysed effect estimates and cross-referenced the evidence with clinical guidelines. Results: We identified 140 systematic reviews, which included 1968 unique randomised controlled trials and 925,364 patients. Reviews contained 100 medications tested in 47 populations. We identified high-to moderate-quality evidence for 28 medications that reduced admissions. Of these medications, 11 were supported by clinical guidelines in the United States, the United Kingdom and Europe. These 11 therapies were for patients with heart failure (angiotensin-converting-enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists and digoxin), stable coronary artery disease (intensive statin therapy), asthma exacerbations (early inhaled corticosteroids in the emergency department and anticholinergics), chronic obstructive pulmonary disease (long-acting muscarinic antagonists and long-acting beta-2 adrenoceptor agonists) and schizophrenia (second-generation antipsychotics and depot/maintenance antipsychotics). Conclusions: We identified 11 medications supported by strong evidence and clinical guidelines that could be considered in quality monitoring and improvement strategies to help reduce emergency hospital admission rates. The findings are relevant to health systems with a large burden of chronic disease and those managing increasing pressures on acute health-care services.
Asymmetric plasmonic nanostructures for manipulation of polarization and absorption of light
Creators: name: Liang, Yao
Publisher: name: Swinburne
Year: 2024

description: This thesis describe some methods to manipulate the polarization and absorption of light using gold nanostructures. These methods would help to build ultra-sensitive chips that can detect disease in small samples of blood or saliva, helping people monitor their health in real-time.
Study of fluorosilicone rubber membrane for pervaporation.
Creators: name: Tsang, Kin-Yip Charles.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Engineering, Chemical.

description: Homogeneous fluorosilicone rubber membranes were prepared to study the dehydration of isopropyl alcohol by pervaporation. The membranes were either water-selective or isopropyl alcohol-selective, depending on the feed composition. The azeotropic composition of isopropyl alcohol-water system predicted using Margules Equation occurred at 41 mole% of water. However, the feed and permeate compositions were found to be equal in pervaporation experiments when the water content in the feed was approximately 70 mole%. Generally, water-selectivity was enhanced by pervaporation as compared to liquid-vapor equilibrium. Composite membranes were also prepared with a thin layer of fluorosilicone rubber coated on top of a porous substrate polyethersulfone membrane. It was found that the performance of the composite membrane was affected by the molecular weight of polyethersulfone used to prepare the porous substrate. The performance of composite membrane became more consistent as the molecular weight of polyethersulfone became more uniform. The membrane selectivity increased with a decrease in the mean pore size.
title: Localización y valoración ecográfica de los nervios periféricos y plexo braquial.
Creators: name: Rozas Rodríguez, María Librada
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Localisation
subject: Ultrasound
subject: Neuroradiology peripheral nerve
subject: Extremities
subject: Anatomy

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir la apariencia normal,
localización y relaciones anatómicas de los principales nervios periféricos y plexo braquial que faciliten su identificación mediante...
Work integration social enterprise (WISE) effects on economic participation, social inclusion, health and wellbeing: evaluation of Vanguard Laundry Services
Creators: name: Elmes, Aurora
Publisher: name: Swinburne
Year: 2024

description: This thesis discusses a multi-year evaluation of Vanguard Laundry Services, a social enterprise in Queensland, Australia employing people with experience of mental illness. Most participants’ incomes increased during employment with Vanguard, but incomes remained relatively low. Most participants reported better health, but some experienced negative effects on health and wellbeing. Effects varied by working conditions and opportunities, with good, inclusive work enabling positive effects.
title: Manifestaciones Radiológicas de la Neumonía en la práctica diaria. Sujeto con patología previa aunque inmunocompetente.
Creators: name: Aguilar García, Jesús José
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Thorax
subject: Management
subject: Conventional radiography

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
La Radiografía Simple de Tórax (RST) es la prueba ‘gold standard’ para el diagnóstico de la neumonía.
En esta comunicación pretendemos revisar los hallazgos radiológicos detectados en la RST,
de sujetos con patología de base aunque...
title: No compactación del miocardio: significado y valor semiológico.
Creators: name: Lucini Pelayo, Germán
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Cardiac
subject: MR

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisaremoslos hallazgos en RM Cardíaca de los síndromes de hipertrabeculación miocárdica. La miocardiopatía no compactada o no compactación del ventrículo izquierdo,
es una miocardiopatía primaria genética consecuencia de un defecto de...
A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients
Creators: name: Author Full Names
name: Hoff, Paula
name: Gaber, Timo
name: Strehl, Cindy
name: Jakstadt, Manuela
name: Hoff, Holger
name: Schmidt-Bleek, Katharina
name: Lang, Ann [U.V.M.]
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: immunologically restricted patients
subject: fracture hematoma
subject: inflammation
subject: fracture healing
subject: bone healing
subject: cytokines
subject: immune cells
subject: chemokines
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Immunologically restricted patients such as those with autoimmune diseases or malignancies often suffer from delayed or insufficient fracture healing. In human fracture hematomas and the surrounding bone marrow obtained from immunologically restricted patients, we analyzed the initial inflammatory phase on cellular and humoral level via flow cytometry and multiplex suspension array. Compared with controls, we demonstrated higher numbers of immune cells like monocytes/macrophages, natural killer T (NKT) cells, and activated T helper cells within the fracture hematomas and/or the surrounding bone marrow. Also, several pro-inflammatory cytokines such as Interleukin (IL)-6 and Tumor necrosis factor α (TNFα), chemokines (e.g., Eotaxin and RANTES), pro-angiogenic factors (e.g., IL-8 and Macrophage migration inhibitory factor: MIF), and regulatory cytokines (e.g., IL-10) were found at higher levels within the fracture hematomas and/or the surrounding bone marrow of immunologically restricted patients when compared to controls. We conclude here that the inflammatory activity on cellular and humoral levels at fracture sites of immunologically restricted patients considerably exceeds that of control patients. The initial inflammatory phase profoundly differs between these patient groups and is probably one of the reasons for prolonged or insufficient fracture healing often occurring within immunologically restricted patients. View Full-Text
Galaxy And Mass Assembly (GAMA): M*-Re relations of z = 0 bulges, discs and spheroids
Creators: name: Lange, Rebecca
name: Moffett, Amanda J.
name: Driver, Simon P.
name: Robotham, Aaron S. G.
name: Lagos, Claudia del P.
name: Kelvin, Lee S.
name: Conselice, Christopher
name: Margalef-Bentabol, Berta
name: Alpaslan, Mehmet
name: Baldry, Ivan
name: Bland-Hawthorn, Joss
name: Bremer, Malcolm
name: Brough, Sarah
name: Cluver, Michelle
name: Colless, Matthew
name: Davies, Luke J. M.
name: Häußler, Boris
name: Holwerda, Benne W.
name: Hopkins, Andrew M.
name: Kafle, Prajwal R.
name: Kennedy, Rebecca
name: Liske, Jochen
name: Phillipps, Steven
name: Popescu, Cristina C.
name: Taylor, Edward
name: Tuffs, Richard
name: van Kampen, Eelco
name: Wright, Angus H.
Publisher: name: Swinburne
Year: 2024

description: We perform automated bulge + disc decomposition on a sample of ˜7500 galaxies from the Galaxy And Mass Assembly (GAMA) survey in the redshift range of 0.002 < z < 0.06 using Structural Investigation of Galaxies via Model Analysis, a wrapper around GALFIT3. To achieve robust profile measurements, we use a novel approach of repeatedly fitting the galaxies, varying the input parameters to sample a large fraction of the input parameter space. Using this method, we reduce the catastrophic failure rate significantly and verify the confidence in the fit independently of χ2. Additionally, using the median of the final fitting values and the 16th and 84th percentile produces more realistic error estimates than those provided by GALFIT, which are known to be underestimated. We use the results of our decompositions to analyse the stellar mass - half-light radius relations of bulges, discs and spheroids. We further investigate the association of components with a parent disc or elliptical relation to provide definite z = 0 disc and spheroid M_star - R_e relations. We conclude by comparing our local disc and spheroid M_star - R_e to simulated data from EAGLE and high-redshift data from Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey-Ultra Deep Survey. We show the potential of using the M_star - R_e relation to study galaxy evolution in both cases but caution that for a fair comparison, all data sets need to be processed and analysed in the same manner.
title: Hiperplasia linfoide reactiva del hígado en un paciente con cáncer de colon: presentación de un caso
Creators: name: Klein, Lea
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Metastases
subject: Biopsy
subject: Outcomes analysis
subject: Ultrasound
subject: CT
subject: Colon
subject: Abdomen
subject: Hyperplasia / Hypertrophy
subject: Liver

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
- Comunicar un caso de hiperplasia linfoide reactiva (HLR) del hígado,
del que hay descritos menos de 35 casos en la literatura,
en un paciente con cáncer de colon con afectación hepática,
sugestiva de metástasis. - Describir el contexto en el...
Netflix’s The Social Dilemma highlights the problem with social media, but what’s the solution?
Creators: name: Barnet, Belinda
name: Bossio, Diana
Publisher: name: Swinburne
Year: 2024

description: Facebook has responded to Netflix documentary The Social Dilemma, saying it "buries the substance in sensationalism". The show is currently in Netflix Australia's top ten list and has been popular around the globe. Some media pundits suggest it's "the most important documentary of our times". The Social Dilemma focuses on how big social media companies manipulate users by using algorithms that encourage addiction to their platforms. It also shows, fairly accurately, how platforms harvest personal data to target users with ads – and have so far gone largely unregulated. But what are we meant to do about it? While the Netflix feature educates viewers about the problems social networks present to both our privacy and agency, it falls short of providing a tangible solution.
Galaxy and Mass Assembly (GAMA): Probing the merger histories of massive galaxies via stellar populations
Creators: name: Ferreras, I.
name: Hopkins, A. M.
name: Gunawardhana, M. L.P.
name: Sansom, A. E.
name: Owers, M. S.
name: Driver, S.
name: Davies, L.
name: Robotham, A.
name: Taylor, Edward
name: Konstantopoulos, I.
name: Brough, S.
name: Norberg, P.
name: Croom, S.
name: Loveday, J.
name: Wang, L.
name: Bremer, M.
Publisher: name: Swinburne
Year: 2024

description: The merging history of galaxies can be traced with studies of dynamically close pairs. These consist of a massive primary galaxy and a less massive secondary (or satellite) galaxy. The study of the stellar populations of secondary (lower mass) galaxies in close pairs provides a way to understand galaxy growth by mergers. Here we focus on systems involving at least one massive galaxy - with stellar mass above 10¹¹M in the highly complete Galaxy and Mass Assembly (GAMA) survey. Our working sample comprises 2692 satellite galaxy spectra (0.1 < z < 0.3). These spectra are combined into high S/N stacks, and binned according to both an 'internal' parameter, the stellar mass of the satellite galaxy (i.e. the secondary), and an 'external' parameter, selecting either the mass of the primary in the pair, or the mass of the corresponding dark matter halo. We find significant variations in the age of the populations with respect to environment. At fixed mass, satellites around the most massive galaxies are older and possibly more metal-rich, with age differences ~1-2 Gyr within the subset of lower mass satellites (~10¹⁰ M). These variations are similar when stacking with respect to the halo mass of the group where the pair is embedded. The population trends in the lower mass satellites are consistent with the old stellar ages found in the outer regions of massive galaxies.
Femme et mère : démocratie et liberté de l'avortement.
Creators: name: Tourigny, Nicole.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Women's Studies.

description: La liberte de l'avortement pose un probleme particulier au regard de l'universel puisqu'elle concerne avant tout des citoyens qui sont aussi designes comme des femmes. Elle concerne une categorie sexuee. On bute sur la differenciation des sexes. Or, ce n'est que depuis un plus d'une vingtaine d'annees que nous pouvons considerer qu'aucun interdit ne frappe plus les femmes dans leurs droits politiques et civils dans les democraties occidentales. La presente these tente de demontrer que la recente plenitude des droits et libertes aurait ete rendu possible par l'abolition de la construction erigee entre "femme et mere". L'hypothese centrale tourne autour de l'idee que le tres grand respect portee a la mere au cours de l'histoire aurait ete un habile artifice pour la tenir a distance du politique. Le passage par la mere grecque et par la mere republicaine en temoignerait. Ce ne serait qu'une fois que les femmes se sont approprie le controle de la maternite, que ce soit par l'utilisation de moyens contraceptifs et en se faisant reconnai tre la liberte d'avorter, que les femmes ont pu etre considerees comme des individus a part entiere. La difference des sexes permet de penser "l'autre" et sert de referent pour dire la communaute, toutefois l'universel exigetait la reconnaissance des singularites de l'un et l'autre des deux sexes.
title: Diseminación perineural de los tumores de cabeza y cuello: Lo que el radiólogo debería conocer
Creators: name: Echeveste Aizpurua, Jon
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Head and neck
subject: Oncology
subject: MR

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir las vías de diseminación perineural más frecuentes. Revisar las conexiones interneurales más frecuentemente implicadas en la diseminación perineural. Conocer con detalle la anatomía en resonancia magnética de los nervios afectados...
TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance
Creators: name: Baas, Marije
name: Besançon, Alix
name: Goncalves, Tania
name: Valette, Fabrice
name: Yagita, Hideo
name: Sawitzki, Birgit
name: Volk, Hans-Dieter
name: Waeckel-Enée, Emmanuelle
name: Rocha, Benedita
name: Chatenoud, Lucienne
name: You, Sylvaine
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: CD8+ T cell anergy is a critical mechanism of peripheral tolerance, poorly investigated in response to immunotherapy. Here, using a pancreatic islet allograft model and CD3 antibody therapy, we showed, by single cell gene profiling, that intragraft CD8+ lymphocytes coexpressing granzyme B and perforin were selectively depleted through the Fas/FasL pathway. This step led to long-standing anergy of the remaining CD8+ T cells marked by the absence of cytotoxic/inflammatory gene expression also confirmed by transcriptome analysis. This sustained unresponsiveness required the presence of the alloantigens. Furthermore, tissue-resident CD8+ lymphocytes produced TGFβ and expressed the inhibitory receptors PD-1 and PD-L1. Blockade of TGFβ downregulated PD-1 and PD-L1 expression and precipitated graft rejection. Neutralizing PD-1, PD-L1 or TGFβRII signaling in T cells also abrogated CD3 antibody-induced tolerance. These studies unravel novel mechanisms underlying CD8+ T cell anergy and reveal a cell intrinsic regulatory link between the TGFβ and the PD-1/PD-L1 pathways.
Public participation at measures to reduce noise in Germany
Creators: name: Zeisler, Annett
Publisher: name: My University
Year: 2014
Subjects: Lärm

description: An essential part of a modern noise reduction strategy is the involvement of the public. This important approach is implemented in the European Environmental Noise Directive. According to this Directive, noise action plans will be developed with the participation of the public. In Germany, the individual participation in planning processes is increasingly in the focus of public interest and in political discussions. Especially, in context of large-scale infrastructure projects such as the expansion of an airport. The goal-oriented implementation of the participation process and the challenges of an effective participation are demonstrated at prominent examples. Moreover, proposals for a further development of the legal requirements of the public participation at EU as well as international level will be presented. In this context, special consideration is given to measures of a clear and effective participation. The aim of these activities is to achieve a higher acceptance for official decisions of great importance. The involvement of the public in the decision-making process could also have a positive effect on their annoyance reaction because noise is often perceived as less loud if people are directly involved in the process.Quelle: http://www.acoustics.asn.au
Glass and plastic waste-added bricks produced from brick clay mill residues by alkali activation at a low temperature
Creators: name: Zhang, Zipeng
Publisher: name: Swinburne
Year: 2024

description: This research investigated an alternative approach to producing bricks from clay, glass and plastic waste without firing and cement. It provides a possibility of manufacturing sustainable bricks with lower energy consumption and carbon emissions. Moreover, this approach has the potential to divert waste materials from landfills by re-purposing them into construction materials.
title: US Arterias Vertebrales.
Creators: name: Collado Jiménez, Jon
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Haemodynamics / Flow dynamics
subject: Ultrasound-Spectral Doppler
subject: Ultrasound
subject: Vascular
subject: Cardiovascular system
subject: Arteries / Aorta

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Identificar patrón presencia y dirección de flujo. Existencia de placas de ateroma. Valorar y analizar los diferentes patrones y manifestaciones US del fenomeno de robo y prerrobo de la...
title: Cirugía bariátrica: Diagnóstico y complicaciones en imagen.
Creators: name: García Vázquez, Maria del Carmen
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Treatment effects
subject: CT
subject: Abdomen

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Evaluar de manera retrospectiva las principales complicaciones de tres técnicas de cirugía bariátrica (by pass,
banda y manga gástrica) así como sus principales características en imagen...
title: Valoración mediante TCMD de la yatrogenia renoureteral.
Creators: name: Escudero Esteban, Raquel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Kidney
subject: CT
subject: Diagnostic procedure
subject: Complications
subject: Pathology

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Utilidad del TCMD para valorar las complicaciones renoureterales derivadas de procedimientos intervencionistas (nefrostomía percutánea y colocación de catéter doble J) dada la importancia en la caracterización del tipo y magnitud del daño,
la...
title: ¿Son útiles los criterios ASAS-OMERACT en el diagnóstico de sacroileitis por RM?. Nuestra experiencia.
Creators: name: López Menéndez, Carlos
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Inflammation
subject: Oedema
subject: Imaging sequences
subject: MR
subject: Musculoskeletal bone
subject: Musculoskeletal joint

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
La sacroileitis constituye un criterio diagnóstico en las espondiloartropatías (EApS). La resonancia magnética de articulaciones sacroiliacas (RM-ASI),
detecta una serie de alteraciones inflamatorias y estructurales,
no patognomónicas,
que...
Decreased microbiome diversity in the HIV small airway epithelium
Creators: name: Xu, Stella
name: Tsai, Amy
name: Sze, Marc A.
name: Vucic, Emily A.
name: Shaipanich, Tawimas
name: Harris, Marianne
name: Guillemi, Silvia
name: Yang, Julia
name: Sinha, Sunita
name: Nislow, Corey
name: Montaner, Julio
name: Lam, Wan
name: Lam, Stephen
name: Sin, Don D.
name: Man, S. F. P.
name: Leung, Janice M.
Publisher: name: BioMed Central
Year: 2018

description: Background: Persons living with human immunodeficiency virus (PLWH) face an increased burden of chronic obstructive pulmonary disease (COPD). Repeated pulmonary infections, antibiotic exposures, and immunosuppression may contribute to an altered small airway epithelium (SAE) microbiome. Methods: SAE cells were collected from 28 PLWH and 48 HIV- controls through bronchoscopic cytologic brushings. DNA extracted from SAE cells was subjected to 16S rRNA amplification and sequencing. Comparisons of alpha and beta diversity between HIV+ and HIV- groups were performed and key operational taxonomic units (OTUs) distinguishing the two groups were identified using the Boruta feature selection after Random Forest Analysis. Results: PLWH demonstrated significantly reduced Shannon diversity compared with HIV- volunteers (1.82 ± 0.10 vs. 2.20 ± 0.073, p = 0.0024). This was primarily driven by a reduction in bacterial richness (23.29 ± 2.75 for PLWH and 46.04 ± 3.716 for HIV-, p < 0.0001). Phyla distribution was significantly altered among PLWH, with an increase in relative abundance of Proteobacteria (p = 0.0003) and a decrease in Bacteroidetes (p = 0.0068) and Firmicutes (p = 0.0002). Six discriminative OTUs were found to distinguish PLWH from HIV- volunteers, aligning to Veillonellaceae, Fusobacterium, Verrucomicrobiaceae, Prevotella, Veillonella, and Campylobacter. Conclusions: Compared to HIV- controls, PLWH’s SAE microbiome is marked by reduced bacterial diversity and richness with significant differences in community composition.
Boden des Jahres 2016
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015
Subjects: subject: Boden des Jahres 2016
subject: Boden | Fläche
subject: Soil | Land

description: Grundwasserböden sind durch oberflächennahes Grundwasser geprägte Böden. Nach der deutschen Bodensystematik heißen diese Böden Gleye. International werden sie Gleysole genannt.
Galaxy and Mass Assembly (GAMA): Exploring the WISE Web in G12
Creators: name: Jarrett, T. H.
name: Cluver, Michelle
name: Magoulas, Christina
name: Bilicki, M.
name: Alpaslan, M.
name: Bland-Hawthorn, J.
name: Brough, S.
name: Brown, M. J.I.
name: Croom, S.
name: Driver, S.
name: Holwerda, B. W.
name: Hopkins, A. M.
name: Loveday, J.
name: Norberg, P.
name: Peacock, J. A.
name: Popescu, C. C.
name: Sadler, E. M.
name: Taylor, Edward
name: Tuffs, R. J.
name: Wang, L.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 510103
subject: Cosmology and extragalactic astronomy

description: We present an analysis of the mid-infrared Wide-field Infrared Survey Explorer (WISE) sources seen within the equatorial GAMA G12 field, located in the North Galactic Cap. Our motivation is to study and characterize the behavior of WISE source populations in anticipation of the deep multiwavelength surveys that will define the next decade, with the principal science goal of mapping the 3D large-scale structures and determining the global physical attributes of the host galaxies. In combination with cosmological redshifts, we identify galaxies from their WISE W1 (3.4 μm) resolved emission, and we also perform a star-galaxy separation using apparent magnitude, colors, and statistical modeling of star counts. The resulting galaxy catalog has ≃590,000 sources in 60 deg2, reaching a W1 5σ depth of 31 μJy. At the faint end, where redshifts are not available, we employ a luminosity function analysis to show that approximately 27% of all WISE extragalactic sources to a limit of 17.5 mag (31 μJy) are at high redshift, z> 1. The spatial distribution is investigated using two-point correlation functions and a 3D source density characterization at 5 Mpc and 20 Mpc scales. For angular distributions, we find that brighter and more massive sources are strongly clustered relative to fainter sources with lower mass; likewise, based on WISE colors, spheroidal galaxies have the strongest clustering, while late-type disk galaxies have the lowest clustering amplitudes. In three dimensions, we find a number of distinct groupings, often bridged by filaments and superstructures. Using special visualization tools, we map these structures, exploring how clustering may play a role with stellar mass and galaxy type.
title: Procedimientos intervencionistas no vasculares urgentes en un hospital comarcal.
Creators: name: Rueda Narvaez, Victoria
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Interventional non-vascular
subject: CT
subject: Ultrasound
subject: Instrumentation

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Repaso de las técnicas intervencionistas no vasculares realizadas de urgencias en nuestro...
title: Valor de la cardio-resonancia ante una sospecha de displasia arritmogénica del ventrículo derecho
Creators: name: Capelastegui, Ana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Dysplasias
subject: MR
subject: Cardiac

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
La Displasia Arritmogénica del VD (DAVD),
también denominada Miocardiopatía Arritmogénica (MCA),
es una cardiomiopatía genética caracterizada por un reemplazamiento fibrograso miocárdico con pérdida de miocitos.
Afecta al VD,
de manera...
title: The Effect of Black Tea on Blood Pressure
title: A Systematic Review with Meta-Analysis of Randomized Controlled Trials
titleType: Subtitle
Creators: name: Greyling, Arno
name: Ras, Rouyanne T.
name: Zock, Peter L.
name: Lorenz, Mario
name: Hopman, Maria T.
name: Thijssen, Dick H. J.
name: Draijer, Richard
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Objective Epidemiological evidence has linked consumption of black tea, produced from Camellia sinensis, with a reduced risk of cardiovascular diseases. However, intervention studies on the effects of tea consumption on blood pressure (BP) have reported inconsistent results. Our objective was to conduct a systematic literature review with meta-analysis of controlled human intervention studies examining the effect of tea consumption on BP. Methods We systematically searched Medline, Biosis, Chemical Abstracts and EMBASE databases through July 2013. For inclusion, studies had to meet the following pre-defined criteria: 1) placebo controlled design in human adults, 2) minimum of 1 week black tea consumption as the sole intervention, 3) reported effects on systolic BP (SBP) or diastolic BP (DBP) or both. A random effects model was used to calculate the pooled overall effect of black tea on BP. Results Eleven studies (12 intervention arms, 378 subjects, dose of 4–5 cups of tea) met our inclusion criteria. The pooled mean effect of regular tea ingestion was −1.8 mmHg (95% CI: −2.8, −0.7; P = 0.0013) for SBP and −1.3 mmHg (95% CI: −1.8, −0.8; P<0.0001) for DBP. In covariate analyses, we found that the method of tea preparation (tea extract powders versus leaf tea), baseline SBP and DBP, and the quality score of the study affected the effect size of the tea intervention (all P<0.05). No evidence of publication bias could be detected. Conclusions Our meta-analysis indicates that regular consumption of black tea can reduce BP. Although the effect is small, such effects could be important for cardiovascular health at population level.
Peer Plus: Trial of a Novel Model of Digitally Assisted Peer Support for Young People Experiencing Psychosis
Creators: name: Peck, Claire
Publisher: name: Swinburne
Year: 2024

description: This digitally-assisted peer support research project involved developing a lived experience-based digital resource for peer support workers to use in sessions with young people who have an experience of psychosis. A key feature of the digital resource was the use of lived experience peer videos to facilitate conversations in one-on-one peer support work sessions. The overall findings provided initial support for the use of this type of digital resource in peer support work, however further research is needed to clarify how a lived experience-based digital resource could be best implemented into peer support work practice within early psychosis services.
title: Trombosis de Labbé una posibilidad diagnostica en neonatos.
Creators: name: jiménez Veintemilla, cristina
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Ultrasound
subject: MR
subject: Paediatric

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Descripción de la anatomía venosa. Descripción de los hallazgos de neuroimagen de laTrombosis de laVena de Labbé en recién nacidos , a propósito de dos casos diagnosticados en nuestro...
Blunted apoptosis of erythrocytes in mice deficient in the heterotrimeric G-protein subunit Gαi2
Creators: name: Bissinger, Rosi
name: Lang, Elisabeth
name: Ghashghaeinia, Mehrdad
name: Singh, Yogesh
name: Zelenak, Christine
name: Fehrenbacher, Birgit
name: Honisch, Sabina
name: Chen, Hong
name: Fakhri, Hajar
name: Umbach, Anja T.
name: Liu, Guilai
name: Rexhepaj, Rexhep
name: Liu, Guoxing
name: Schaller, Martin
name: Mack, Andreas F.
name: Lupescu, Adrian
name: Birnbaumer, Lutz
name: Lang, Florian
name: Qadri, Syed M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Putative functions of the heterotrimeric G-protein subunit Gαi2-dependent signaling include ion channel regulation, cell differentiation, proliferation and apoptosis. Erythrocytes may, similar to apoptosis of nucleated cells, undergo eryptosis, characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine (PS) exposure. Eryptosis may be triggered by increased cytosolic Ca2+ activity and ceramide. In the present study, we show that Gαi2 is expressed in both murine and human erythrocytes and further examined the survival of erythrocytes drawn from Gαi2-deficient mice (Gαi2−/−) and corresponding wild-type mice (Gαi2+/+). Our data show that plasma erythropoietin levels, erythrocyte maturation markers, erythrocyte counts, hematocrit and hemoglobin concentration were similar in Gαi2−/− and Gαi2+/+ mice but the mean corpuscular volume was significantly larger in Gαi2−/− mice. Spontaneous PS exposure of circulating Gαi2−/− erythrocytes was significantly lower than that of circulating Gαi2+/+ erythrocytes. PS exposure was significantly lower in Gαi2−/− than in Gαi2+/+ erythrocytes following ex vivo exposure to hyperosmotic shock, bacterial sphingomyelinase or C6 ceramide. Erythrocyte Gαi2 deficiency further attenuated hyperosmotic shock-induced increase of cytosolic Ca2+ activity and cell shrinkage. Moreover, Gαi2−/− erythrocytes were more resistant to osmosensitive hemolysis as compared to Gαi2+/+ erythrocytes. In conclusion, Gαi2 deficiency in erythrocytes confers partial protection against suicidal cell death.
title: Carcinoma Lobulillar. Manejo diagnóstico.
Creators: name: Guzman Aroca, Florentina
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Breast
subject: Oncology
subject: Mammography
subject: Ultrasound
subject: MR-Functional imaging
subject: Diagnostic procedure
subject: Imaging sequences
subject: Pathology
subject: Neoplasia

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo de nuestro estudio es analizar los métodos de imagen utilizados para el diagnóstico de carcinoma lobulillarinvasivo y los hallazgos radiológicos...