cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effects of anisotropy of turbulent convection in mean-field solar dynamo models
Creators: name: Pipin, V. V.
name: Kosovichev, A. G.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We study how anisotropy of turbulent convection affects diffusion of large-scale magnetic fields and the dynamo process on the Sun. The effect of anisotropy is calculated in a mean-field magneto-hydrodynamics framework using the minimal $τ$-approximation. We examine two types of mean-field dynamo models: the well-known benchmark flux-transport model, and a distributed-dynamo model with the subsurface rotational shear layer. For both models we investigate effects of the double-cell meridional circulation, recently suggested by helioseismology. We introduce a parameter of anisotropy as a ratio of the radial and horizontal intensity of turbulent mixing, to characterize the anisotropy effects. It is found that the anisotropy of turbulent convection affects the distribution of magnetic fields inside the convection zone. The concentration of the magnetic flux near the bottom and top boundaries of the convection zone is greater when the anisotropy is stronger. It is shown that the critical dynamo number and the dynamo period approach to constant values for the large anisotropy parameter. The anisotropy reduces the overlap of the toroidal fields of subsequent cycles in the time-latitude ``butterfly' diagram. If we assume that sunspots are formed in the vicinity of the subsurface shear layer, then the distributed dynamo model with anisotropic diffusivity satisfies the observational constraints from heloseismology results and is consistent with the value of effective turbulent diffusion, estimated from the dynamics of surface magnetic fields.
description: 22 pages, 6 figures, R2(add results for the model with triple cell circulation)
Additional file 1 of Home-based training technology for persons with dementia: a qualitative study of barriers and facilitators for mobility-based training at home
Creators: name: Ladekjær Larsen, Eva
name: Waldorff, Frans Boch
name: Hansen, Helle Ploug
name: la Cour, Karen
Publisher: name: figshare
Year: 2022
Subjects: subject: Neuroscience
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Interview guides.
Asymmetric Gepner models in type II
Creators: name: Israel, Dan
name: Thiery, Vincent
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We describe new four-dimensional type II compactifications with N=2 supersymmetry, based on asymmetric Gepner models for K3 x T^2. In more than half of these models, all the K3 moduli are lifted, giving at low energies N=2 supergravity with the STU vector multiplets and no hypermultiplets.
description: 18 pages; v2: few typos corrected, references added ; v3: few modifications in the text, results unchanged, published version
Non-Abelian Chern-Simons Theory from a Hubbard-like Model
Creators: name: Palumbo, Giandomenico
name: Pachos, Jiannis K.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Here, we provide a simple Hubbard-like model of spin-$1/2$ fermions that gives rise to the SU(2) symmetric Thirring model that is equivalent, in the low-energy limit, to Yang-Mills-Chern-Simons model. First, we identify the regime that simulates the SU(2) Yang-Mills theory. Then, we suitably extend this model so that it gives rise to the SU(2) level $k$ Chern-Simons theory with $k\geq2$ that can support non-Abelian anyons. This is achieved by introducing multiple fermionic species and modifying the Thirring interactions, while preserving the SU(2) symmetry. Our proposal provides the means to theoretically and experimentally probe non-Abelian SU(2) level $k$ topological phases.
description: 4.5 pages, 3 figures, published version
Dubrovin-Zhang hierarchy for the Hodge integrals
Creators: name: Buryak, A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In this paper we prove that the generating series of the Hodge integrals over the moduli space of stable curves is a solution of a certain deformation of the KdV hierarchy. This hierarchy is constructed in the framework of the Dubrovin-Zhang theory of the hierarchies of the topological type. It occurs that our deformation of the KdV hierarchy is closely related to the hierarchy of the Intermediate Long Wave equation.
description: Final version, 20 pages
Plaquette valence-bond solid in the square lattice J1-J2 antiferromagnet Heisenberg model: a bond operator approach
Creators: name: Doretto, R. L.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the plaquette valence-bond solid phase of the spin-1/2 J_1-J_2 antiferromagnet Heisenberg model on the square lattice within the bond-operator theory. We start by considering four S = 1/2 spins on a single plaquette and determine the bond operator representation for the spin operators in terms of singlet, triplet, and quintet boson operators. The formalism is then applied to the J_1-J_2 model and an effective interacting boson model in terms of singlets and triplets is derived. The effective model is analyzed within the harmonic approximation and the previous results of Zhitomirsky and Ueda [Phys. Rev. B 54, 9007 (1996)] are recovered. By perturbatively including cubic (triplet-triplet-triplet and singlet-triplet-triplet) and quartic interactions, we find that the plaquette valence-bond solid phase is stable within the parameter region 0.34 < J_2/J_1 < 0.59, which is narrower than the harmonic one. Differently from the harmonic approximation, the excitation gap vanishes at both critical couplings J_2 = 0.34 J_1 and J_2 = 0.59 J_1. Interestingly, for J_2 < 0.48 J_1, the excitation gap corresponds to a singlet-triplet excitation at the $Γ$ point while, for J_2 > 0.48 J_1, it is related to a singlet-singlet excitation at the X = (pi/2,0) point of the tetramerized Brillouin zone.
description: 17 pages, 12 figures, effects quartic interactions included, final version
Fermi liquid theory of resonant spin pumping
Creators: name: Moca, C. P.
name: Alex, A.
name: Shnirman, A.
name: Zarand, G.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study resonant all-electric adiabatic spin pumping through a quantum dot with two nearby levels by using a Fermi liquid approach in the strongly interacting regime, combined with a projective numerical renormalization group (NRG) theory. Due to spin-orbit coupling, a strong spin pumping resonance emerges at every charging transition, which allows for the transfer of a spin $~ \hbar/2$ through the device in a single pumping cycle. Depending on the precise geometry of the device, controlled pure spin pumping is also possible.
description: 5 pages, 5 figures
Sensitive dependence of isotope and isobar distribution of limiting temperatures on symmetry energy
Creators: name: Ou, Li
name: Liu, Min
name: Li, Zhuxia
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The mass, isotope, and isobar distributions of limiting temperatures for finite nuclei are investigated by using a thermodynamics approach together with the Skyrme energy density functional. The relationship between the width of the isotope (isobar) distribution of limiting temperatures and the stiffness of the density dependence of the symmetry energy clearly is observed. The nuclear symmetry energy with smaller slope parameter $L_{\rm{sym}}$ causes a wider the isotope (isobar) distribution of limiting temperatures. The widths of the isotope (isobar) distributions of limiting temperatures could be useful observables for exploring the information of the density dependence of the nuclear symmetry energy at finite temperatures.
description: 17 pages, 7 figures
Effects of a static electric field on two-color photoassociation between different atoms
Creators: name: Chakraborty, Debashree
name: Deb, Bimalendu
Publisher: name: arXiv
Year: 2013
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We study non-perturbative effects of a static electric field on two-color photoassociation of different atoms. A static electric field induces anisotropy in scattering between two different atoms and hybridizes field-free rotational states of heteronuclear dimers or polar molecules. In a previous paper [D. Chakraborty $\it {et.}$ $\it {al.}$, J. Phys. B 44, 095201 (2011)], the effects of a static electric field on one-color photoassociation between different atoms has been described through field-modified ground-state scattering states, neglecting electric field effects on heteronuclear diatomic bound states. To study the effects of a static electric field on heteronuclear bound states, and the resulting influence on Raman-type two-color photoassociation between different atoms in the presence of a static electric field, we develop a non-perturbative numerical method to calculate static electric field-dressed heteronuclear bound states. We show that the static electric field induced scattering anisotropy as well as hybridization of rotational states strongly influence two-color photoassociation spectra, leading to significant enhancement in PA rate and large shift. In particular, for static electric field strengths of a few hundred kV/cm, two-color PA rate involving high-lying bound states in electronic ground-state increases by several orders of magnitude even in the weak photoassociative coupling regime.
Quantum Exact Non-Abelian Vortices in Non-relativistic Theories
Creators: name: Nitta, Muneto
name: Uchino, Shun
name: Vinci, Walter
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: Non-Abelian vortices arise when a non-Abelian global symmetry is exact in the ground state but spontaneously broken in the vicinity of their cores. In this case, there appear (non-Abelian) Nambu-Goldstone (NG) modes confined and propagating along the vortex. In relativistic theories, the Coleman-Mermin-Wagner theorem forbids the existence of a spontaneous symmetry breaking, or a long-range order, in 1+1 dimensions: quantum corrections restore the symmetry along the vortex and the NG modes acquire a mass gap. We show that in non-relativistic theories NG modes with quadratic dispersion relation confined on a vortex can remain gapless at quantum level. We provide a concrete and experimentally realizable example of a three-component Bose-Einstein condensate with U(1) x U(2) symmetry. We first show, at the classical level, the existence of S^3 = S^1 |x S^2 (S^1 fibered over S^2) NG modes associated to the breaking U(2) -> U(1) on vortices, where S^1 and S^2 correspond to type I and II NG modes, respectively. We then show, by using a Bethe ansatz technique, that the U(1) symmetry is restored, while the SU(2) symmery remains broken non-pertubatively at quantum level. Accordingly, the U(1) NG mode turns into a c=1 conformal field theory, the Tomonaga-Luttinger liquid, while the S^2 NG mode remains gapless, describing a ferromagnetic liquid. This allows the vortex to be genuinely non-Abelian at quantum level.
description: 20 pages, 2 figures, v2: minor changes
Portrait des tâches et des activités des chefs d'établissement : revue rapide
Creators: name: AL-CHIKH, Insaf
name: Alladatin, Judicaël
name: ROCHE, Lionel
Publisher: name: Zenodo
Year: 2022
Subjects: administration scolaire
direction d'établissement scolaire
activités
leadership
tâches

description: Le rôle du directeur d'école a évolué au fil des ans, devenant de plus en plus exigeant et complexe (Hancock et al., 2019). Outre l’augmentation des tâches et la complexité croissante des activités des chefs d’établissement, la société leur demande également de jouer un rôle beaucoup plus important dans la communauté, étant donné leur responsabilité dans l'exécution des ordres gouvernementaux, le développement de l'éducation (Nilsson et al., 2022), et la mise en place des diverses demandes des élèves et des parents (Markow et al., 2013). Pour exécuter ces tâches qui leur sont assignées, les chefs d'établissement scolaire s'engagent dans une variété d'activités quotidiennes. Il devrait être utile donc de lister les tâches et de décrire les activités quotidiennes des chefs d'établissement afin de pouvoir développer des programmes de formation basés sur les réalités des établissements d'enseignement, ainsi que pour leur apporter une aide supplémentaire (Albendea & Cuadrado, 2017). Cette étude propose une classification exploratoire de la littérature internationale sur les différentes activités et les tâches dont le directeur d'école est responsable. Pour cela, Nous avons effectué une recherche électronique pour localiser et récupérer la littérature académique pertinente (Goodman et al., 2014), en effectuant des recherches dans les moteurs de recherches suivants : Web of science, JSTOR, SAGE, et la littérature grise pour identifier les études de révision de la portée, notamment la bases de données : Google Scholar (GS), ainsi que des enquêtes, des livres et des chapitres de livres... Apres dépouillement de la littérature collectée, notre analyse s’est basé sur une revue rapide de 20 documents publiés les 10 dernières années. Le résultat de cette recherche aboutit à l'émergence de huit grandes catégories de types d’activités du chef d'établissement : gestion du programme scolaire, création d'un environnement scolaire favorable, gestion de la communauté/relations avec les parents, gestion des affaires scolaires, développement professionnel, gestion du personnel scolaire, définition de la mission de l'école et fixation des objectifs, amélioration des performances de l'école et leadership pédagogique. Il ressort également que des facteurs tels que le pays, le niveau scolaire (élémentaire/moyen/secondaire), la taille de l'école (effectifs), la diversité du corps étudiant et les performances scolaires des élèves influencent le fonctionnement du travail des directeurs d'école et donc les types d'activités qu'ils réalisent. Cette étude en fournissant une vision large sur l’éventail des types d’activités des chefs d’établissements scolaires, offre ainsi des perspectives intéressantes en termes de sélection et d’amélioration des contenus formation des dirigeants scolaires en tenant compte éventuellement des adaptations idoines selon le contexte.
Large scale index of multi-partitioned manifolds
Creators: name: Schick, Thomas
name: Zadeh, Mostafa Esfahani
Publisher: name: arXiv
Year: 2013
Subjects: subject: K-Theory and Homology (math.KT)
subject: Differential Geometry (math.DG)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: Let M be a complete n-dimensional Riemannian spin manifold, partitioned by q two-sided hypersurfaces which have a compact transverse intersection N and which in addition satisfy a certain coarse transversality condition. Let E be a Hermitean bundle with connection on M. We define a coarse multi-partitioned index of the spin Dirac operator on M twisted by E. Our main result is the computation of this multi-partitioned index as the Fredholm index of the Dirac operator on the compact manifold N, twisted by the restriction of E to N. We establish the following main application: if the scalar curvature of M is bounded from below by a positive constant everywhere (or even if this happens only on one of the quadrants defined by the partitioning hypersurfaces) then the multi-partitioned index vanishes. Consequently, ind(D_N) is an obstruction to uniformly positive scalar curvature on M. The proof of the multi-partitioned index theorem proceeds in two steps: first we establish a strong new localization property of the multi-partitioned index which is the main novelty of this note. This we establish even when we twist with an arbitrary Hilbert A-module bundle E (for an auxiliary C*-algebra A). This allows to reduce to the case where M is the product of a compact manifold with Euclidean space. For this special case, standard methods for the explicit calculation of the index in this product situation can be adapted to obtain the result.
description: 14 pages, AMS-latex; v3 is a substantial revision, following many suggestions of the referee, v4 final version to appear in Journal of Non-commutative Geometry; v5 correction of v4, where by accident an outdated version was uploaded
Restoring General Relativity in massive bi-gravity theory
Creators: name: Babichev, Eugeny
name: Crisostomi, Marco
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study static spherically symmetric solutions of massive bi-gravity theory, free from the Boulware-Deser ghost. We show the recovery of General Relativity via the Vainshtein mechanism, in the weak limit of the physical metric. We find a single polynomial equation determining the behavior of the solution for distances smaller than the inverse graviton mass. This equation is generically of the seventh order, while for a specific choice of the parameters of the theory it can be reduced to lower orders. The solution is analytic in different regimes: for distances below the Vainshtein radius (where General Relativity is recovered), and in the opposite regime, beyond the Vainshtein radius, where the solution approaches the flat metric.
description: 18 pages, 10 figures, typos corrected, version published in PRD
A new family of exact and rotating solutions of fireball hydrodynamics
Creators: name: Csörgő, T.
name: Nagy, M. I.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A new class of analytic, exact, rotating, self-similar and surprisingly simple solutions of non-relativistic hydrodynamics are presented for a three-dimensionally expanding, spheroidally symmetric fireball. These results generalize earlier, non-rotating solutions for ellipsoidally symmetric fireballs with directional, three-dimensional Hubble flows. The solutions are presented for a general class of equations of state that includes the lattice QCD equations of state and may feature inhomogeneous temperature and corresponding density profiles.
description: Dedicated to T. Kodama on the occasion of his 70th birthday. 15 pages, no figures. Accepted for publication at Phys. Rev. C. Minor rewritings from previous version
THICK AND THIN CHARACTERS:ORGANISMAL FORM AND REPRESENTATIONAL PRACTICE IN EMBRYOLOGY AND GENETICS
Creators: name: MEUNIER, ROBERT KARL
Publisher: name: Universit� degli Studi di Milano
Year: 2012

description: In this thesis the family of concepts, including characters, traits and phenotypes of organisms is analyzed according to the various roles these concepts play in different disciplines and in different historical periods. The ways the concepts are construed in order to fulfill their roles are spelled out in terms of the representational practices in which these concepts are embedded. In particular, I look at classical genetics in the period spanning from Mendel to Morgan and compare the character concept that gradually developed in this period ? and which I characterize as a thin concept, meaning that characters appear as values of variables that are represented in articulated symbol systems ? with the thick concept of parts, properties and processes as it prevails in anatomy, physiology and embryology. In order to illustrate that both concepts still play their role in modern biology and to address the question of their possible integration, I conclude by briefly looking at current developmental genetics. I address the general issue of scientific pluralism in Chapter 1. Chapter 2 and 3 introduce the methodological concepts necessary to analyze the representational practices that embody the various character concepts. Chapters 4, 5, 6 and the Conclusion contain the discussion of the character concepts in the disciplines taken into consideration.
NAUTILOS D11.1 - Nautilos Exploitation Strategy
Creators: name: Torres, Armindo
Publisher: name: Zenodo
Year: 2021
Subjects: www.nautilos-h2020.eu

description: The deliverable will provide the Exploitation and IPR Management Strategy of NAUTILOS. It will outline the strategical context and provide the NAUTILOS Strategy Statement as well as cover the baseline access rights and IPRs (i.e. Background, Foreground, Sideground, Postground), risk analysis and mitigation measures for the NAUTILOS project
On the gauge symmetries of Maxwell-like higher-spin Lagrangians
Creators: name: Francia, D.
name: Lyakhovich, S. L.
name: Sharapov, A. A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: In their simplest form, metric-like Lagrangians for higher-spin massless fields display constrained gauge symmetries, unless auxiliary fields are introduced or locality is foregone. Specifically, in its standard incarnation, gauge invariance of Maxwell-like Lagrangians relies on parameters with vanishing divergence. We propose an alternative form of the corresponding local symmetry involving unconstrained parameters of mixed-symmetry type, described by rectangular two-row Young diagrams and entering high-derivative gauge transformations. The resulting gauge algebra appears to be reducible and we display the full pattern of gauge-for-gauge parameters, testing its correctness via the corresponding counting of degrees of freedom. Incidentally, this shows that massless higher spins admit a local unconstrained formulation with no need for auxiliary fields.
description: 24 pages; minor changes in the Introduction, references added. To appear in Nucl. Phys. B
Complete stability analysis of a heuristic ADP control design
Creators: name: Sokolov, Yury
name: Kozma, Robert
name: Werbos, Ludmilla D.
name: Werbos, Paul J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Neural and Evolutionary Computing (cs.NE)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This paper provides new stability results for Action-Dependent Heuristic Dynamic Programming (ADHDP), using a control algorithm that iteratively improves an internal model of the external world in the autonomous system based on its continuous interaction with the environment. We extend previous results by ADHDP control to the case of general multi-layer neural networks with deep learning across all layers. In particular, we show that the introduced control approach is uniformly ultimately bounded (UUB) under specific conditions on the learning rates, without explicit constraints on the temporal discount factor. We demonstrate the benefit of our results to the control of linear and nonlinear systems, including the cart-pole balancing problem. Our results show significantly improved learning and control performance as compared to the state-of-art.
description: 20 pages
THE IMPACT OF DIFFERENT ENERGY POLICY OPTIONS ON FEEDSTOCK PRICE AND LAND DEMAND: THE CASE OF BIOGAS IN LOMBARDY.
Creators: name: BARTOLI, ANDREA
Publisher: name: Universit� degli Studi di Milano
Year: 2015

description: The effectiveness of bioenergy subsidisation policy in greenhouse gas mitigation and their hypothetical effect on the increase of the agricultural commodity prices, have led to a lively debate at the international level. The issue recurred in Italy as well, as a consequence of the growing demand of green maize for biogas production in the Po Valley. Such emerging activity has been accused to increase land rents and maize price, jeopardizing, in turn, important agri-food chains. The aim of this thesis is to quantify the extent to which the rapid spread of biogas raised the maize price at regional level, increasing the demand of land for energy crops. For this purpose we built a partial-equilibrium model simulating the agricultural sector and the biogas industry in Lombardy, under two alternative subsidization schemes. Results show that policy measures implemented in 2013 ? reducing the average subsidy per kWh ? may contribute to enforce the sustainability of the sector and decreasing its competition with agri-food chains: Maize demand for biogas would decrease, compared to the old scheme, lessening the market clearing price and reducing land demand for energy purposes.
KLF4 IS A KEY DETERMINANT IN THE DEVELOPMENT AND PROGRESSION OF CEREBRAL CAVERNOUS MALFORMATIONS
Creators: name: CUTTANO, ROBERTO
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: Cerebral cavernous malformations (CCMs) are capillary-venous malformations located in the central nervous system that often lead to neurological deficits and cerebral hemorrhage. Pharmacological treatment limiting disease progression is dearly needed, as available therapy is limited to surgical lesion eradication or stereotactic radiosurgery. CCM affects up to 0.5% of the human population and can occur either in a sporadic or familial form. Loss-of-function mutations in any of three genes CCM1, CCM2 and CCM3 have been associated to familial CCM. Postnatal endothelial-specific deletion of any of the three Ccm genes in mice results in the development of multiple brain vascular malformations that faithfully resemble human CCM lesions. Here we describe that CCM malformations are formed by endothelial cells (ECs) undergoing endothelial-to-mesenchymal transition (EndMT), a phenotype that recapitulates most of the previously observed functional changes that are responsible for dysplasia and fragility of CCM lesions. Ccm1 deletion leads to activation of the MEKK3-MEK5-ERK5-MEF2 signaling cascade resulting in a marked upregulation of the transcription factor Kru?ppel-like factor 4 (KLF4) in ECs in vivo. KLF4 promotes an endogenous production of bone morphogenetic protein 6 (BMP6) in ECs that, in turn, activates the transforming growth factor-? (TGF-?) and bone morphogenetic protein (BMP) signalling pathway. KLF4 transcriptional activity and KLF4-dependent TGF-?/BMP pathway activation are responsible for the EndMT switch observed in the absence of Ccm1. Interestingly, using both a pharmacological treatment to inhibit TGF-?/BMP pathway or a genetic approach based on endothelial-specific Ccm1 and Klf4 double knockout mice, we strongly reduce the development and progression of CCM lesions. Importantly loss of Klf4 almost abolishes mouse mortality due to brain hemorrhage in endothelial Ccm1-ablated mice. These data indicate that KLF4, TGF- ?/BMP pathway and EndMT are crucial events for CCM pathogenesis and unveil KLF4 as a key therapeutic target for CCM.
Time-dependent quantum transport: causal superfermions, exact fermion-parity protected decay mode, and Pauli exclusion principle for mixed quantum states
Creators: name: Saptsov, R. B.
name: Wegewijs, M. R.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We extend the recently developed causal superfermion approach to the real-time transport theory to time-dependent decay problems.Its usefulness is illustrated for the Anderson model of a quantum dot with tunneling rates depending on spin due to the ferromagnetic electrodes and/or spin polarization of the tunnel junction. We set up a second quantization scheme for density operators in the Liouville-Fock space constructing causal field superoperators using the fundamental physical principles of causality/probability conservation and the fermion-parity superselection (univalence). The time-dependent perturbation series for the time-evolution is renormalized by explicitly performing the wide-band limit on the superoperator level. The short and long-time reservoir correlations are shown to be tightly linked to the occurrence of causal field destruction and creation superoperators, respectively. The effective theory takes as a reference a damped local system, providing an interesting starting point for numerical calculations of memory kernels in real-time. A remarkable feature of this approach is the natural appearance of a measurable fermion-parity protected decay mode. It already can be calculated exactly in the Markovian, infinite temperature limit by leading order perturbation theory, yet persists unaltered for the finite temperature, interaction and tunneling spin polarization. Furthermore, we show how a Liouville-space analog of the Pauli principle directly leads to the exact result in the noninteracting limit: surprisingly, it is obtained in finite (second) order renormalized perturbation theory, both for the self-energy as well as the time-evolution propagator. For this limit we calculate the time-evolution of the full density operator starting from an arbitrary initial state on the quantum dot, including spin and pairing coherences and two-particle correlations.
description: This version contains the more extensive introduction and the conclusion, discussing an experimental relevance of the obtained exact result for the new decay mode. A lot of new references have been added. The more detailed comparison of the results obtained for the noninteracting case with the known results has been done. Small typos have been fixed
FUNCTIONAL AND GENETIC HETEROGENEITY IN ACUTE MYELOID LEUKAEMIA
Creators: name: VLACHOU, THALEIA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Acute myeloid leukaemia (AML) is the most frequent leukaemia in adults, and still represents a disease with an unmet medical need, with 50-60% of patients relapsing within 3 years after diagnosis. AMLs are characterised by a high degree of intra-tumour heterogeneity, both at the biological and the genetic level, which is critical for tumour maintenance and response to treatments. Biologically, AMLs are organised hierarchically, with rare stem-like cells (leukaemia stem cells, LSCs) endowed with the unique properties of self-renewal and differentiation. Genetically, AMLs harbour patient-specific combinations of different driver mutations, which are organised within individual cases in sub-clones with distinct growth properties. We hypothesized that tumour maintenance and relapse in AMLs are driven by the selective expansion of quiescent sub-clones within the LSC population, which serve as the genomic and functional reservoir of the tumour. The experimental strategy we employed to test this hypothesis is based on the xenotransplantation of human leukaemias, the implementation of an in vivo clonal tracking approach, the functional isolation of leukaemic subpopulations with diverse proliferation histories and whole-exome sequencing (WES) of bulk and isolated leukaemic subpopulations. Our aims were to assess the proliferative hierarchy of LSCs and to examine their intrinsic genetic heterogeneity. We identified two functional LSC classes, quiescent and cycling, that are in equilibrium in the tumour and largely share the same clonal architecture. We further observed that genetic leukaemic clones appear to consist of a high number of individual LSCs, the majority of which exhaust upon serial transplantation. Finally, by genetic analyses of isolated leukaemic subsets, we were able to detect a specific enrichment for rare mutations in the quiescent compartment of two patient xenografts. Our data indicate that tumour evolution is sustained by the quiescent LSC pool and suggest that their highly proliferating counterpart has a finite lifespan. We expect that the results of our studies will provide new insights into the mechanisms of disease progression and treatment response in AML, and potentially reveal novel therapeutic approaches.
L'AMMINISTRAZIONE DELL'UNIONE DOGANALE EUROPEA
Creators: name: PARISI, EDUARDO
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: La tesi ha ad oggetto l?analisi dell?Unione doganale europea ? nucleo originario delle Comunit� e strumento principale per il perseguimento del mercato unico ? quale sistema composito di diritto amministrativo europeo. Al fine di comprendere le modalit� e i limiti dell?esercizio del potere da parte dell?Unione doganale europea, nonch� l?intreccio di relazioni esistenti fra soggetti coinvolti nel rapporto doganale, vengono esaminati, in seguito una contestualizzazione storico-economica dell?oggetto di studio, il riparto di competenze, le modalit� di esercizio dell?azione amministrativa e i modelli organizzativi propri del sistema. La ricerca porta a delineare un modello di amministrazione non gi� unitario e uniforme, bens� poliedrico e difficilmente riconducibile ai noti modelli di azione amministrativa europea e caratterizzato, da un lato, dalla compresenza di diversi soggetti che operano per il perseguimento del medesimo fine, pur secondo un rigido riparto di competenze, e, dall?altro lato, dalla presenza di regole e principi propri del diritto amministrativo europeo che si impongono sugli ordinamenti degli Stati membri, come avviene nei cosiddetti ?sistemi comuni?.
THE UBIQUITIN-SPECIFIC PROTEASE USP14 CONTROLS CILIOGENESIS AND THE HEDGEHOG PATHWAY
Creators: name: MASSA, FILOMENA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: Primary cilia are microtubule-based organelles on the apical surface of mammalian cells, and play a crucial role in vertebrate development and tissue homeostasis. Consequently, ciliary defects are associated with human disorders called ciliopathies. This organelle represents an organizing center for signaling pathways. In particular, in vertebrates, the Hedgehog (Hh) pathway controls embryonic development and adult homeostasis using the primary cilium to transduce its signal. Hh components localize to cilia and Kif7, a key player in cilia structure and length, controls the ciliary localization of Hh signaling molecules. Phenotypes associated to Hh signaling impairment are often observed in ciliopathies. Recent studies established a link between ciliary proteins and the Ubiquitin proteasome system (UPS) pathway, however much remains to be understood. The main role of the UPS is to mark proteins for degradation although it also functions in a wide variety of cellular processes. The aim of my PhD project was to investigate the association between cilioproteins and proteasomal functions, with particular emphasis on the cilia- associated OFD1 protein, which is responsible for the rare OFD type I syndrome. The results obtained demonstrate that OFD1 controls proteasomal complex composition through direct binding with proteasomal components (see Liu et al. in appendix). Our results also demonstrate a role for Usp14, a deubiquitinating enzyme, in the control of ciliogenesis, cilia length and proper activation of the Hh pathway. We propose a new mechanism by which cilia maintenance and the Hh pathway are regulated by Usp14 via modulation of Kif7 proteasomal degradation (manuscript in preparation). This mechanism may be relevant not only in ciliopathies but also in other pathological conditions associated to Hedgehog signaling defects. Overall our results provide new insight into the spectrum of action of the UPS and may provide novel opportunities for therapeutic intervention in pathological conditions associated to cilia dysfunction.
NAUTILOS D8.4 - Design of Thematic Assembly centre for innovative parameters
Creators: name: Novellino, Antonio
name: Colombo, Federica
Publisher: name: Zenodo
Year: 2021
Subjects: www.nautilos-h2020.eu

description: NAUTILOS is developing innovative sensors, some are going to improve the actual sensor accuracy and resolution, some others are tackling the acquisition of new parameters. The deliverable describes common methods for parameter-platform management, from collection (and procedures for data quality insurance) to dissemination. Dissemination considers standards and methods to facilitate interoperability towards other European Infrastructure such as EMODnet, CMEMS, SeaDataNet etc. This document defines the methodology and the structure to implement a Thematic data Assembly centre (TAC) for parameters and data streams that are not yet consolidated under a European or International Data/Thematic assembly centre nor under one of the major European data infrastructures.
THE FABRIC OF KNOWLEDGE. TOWARDS A DOCUMENTAL HISTORY OF LATE ANALYTIC PHILOSOPHY
Creators: name: PETROVICH, EUGENIO
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: The dissertation aims at presenting an innovative approach (called �documental history�) to the study of the history of contemporary philosophy, focusing on the case of Late Analytic Philosophy (LAP). The methodological innovation consists in the application of citation analysis techniques, drawn from the field of scientometrics, to the analysis of the structure and the dynamics of LAP. The main empirical results are presented in four scientometric analyses of LAP, which focus, respectively, on the scientometric distributions of LAP, the co-citation mapping of LAP, the epistemological function of citations within LAP, and the aging of LAP literature. The main theoretical result is the �feedback hypothesis�, according to which the �documental space� of LAP shapes the intellectual behavior of analytic philosophers. Thus, the documental space of LAP should be accounted as a factor of philosophical change, besides the traditional intellectual and sociological factors. A key aspect of the dissertation is the interdisciplinary integration of distant fields, such as scientometrics, history of philosophy, and philosophy of science.
TURIZM SOHАSIDАGI KICHIK BIZNES MUАMMOLАRI VА ISTIQBOLLАRI
Creators: name: Ahmadjonov Abdurasul Tursunali o'g'li  Marg'ilon turizm va madaniy meros texnikumi o'qituvchisi
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolada O‘zbekiston Respublikasida faoliyat olib borayotgan erkin turistik korxonalar va kichik sanoat zonalari majmui,ularni rivojlantirishda va kengaytirishda investitsiyalar jalb etish va ulardan samarali foydalanish jarayonlarini ifodalovchi ijtimoiy-iqtisodiy tizimlar jamlammasi yoritib o‘tilgan.

 Kalit so‘zlar. Kichik turistik korxonalar,kichik biznes,xususiy tadbirkorlik,servis, bozor infratuzilmasi
Quantum corrections to the dynamics of the expanding universe
Creators: name: Kuzmichev, V. E.
name: Kuzmichev, V. V.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The dynamics of the expanding universe is analyzed in terms of the quantum geometrodynamical model. It is shown that the equations of quantum theory in the form of the eigenvalues equation similar to the stationary Schrödinger equation complemented by the equations of motion for the momentum operator and its time derivative in Heisenberg's form reduce to the Einstein equations with an additional source of the gravitational field of quantum nature. The spatially closed universe with cosmological constant, originally filled with a uniform scalar field and radiation, is considered as quantum cosmological system. The perfect fluid in the form of radiation defines the material reference frame. The properties of the averaged scalar field which acts like ordinary matter are investigated. After averaging over its quantum states, the free scalar field turns into the Weyssenhoff fluid characterized by the energy density, pressure, and spin of constituent particles. The cases when the contribution of the quantum effects into the gravitational interaction becomes significant on macroscopic scale are analyzed. It is demonstrated that, unless the whole, at least a part of such matter-energy constituents as dark matter and dark energy may have a quantum origin.
description: 20 pages, v.2: a few sections are revised, new references
WEBINAR: Here's one we prepared earlier: (re)creating bioinformatics methods and workflows with Galaxy Australia
Creators: name: Price, Gareth
name: Gustafsson, Johan
Publisher: name: Zenodo
Year: 2022
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Workflows
subject: FAIR
subject: Galaxy Australia
subject: http://edamontology.org/topic_0091
subject: http://edamontology.org/topic_0769

description: This record includes training materials associated with the Australian BioCommons webinar ‘Here’s one we prepared earlier: (re)creating bioinformatics methods and workflows with Galaxy Australia’. This webinar took place on 26 October 2022. Event description  Have you discovered a brilliant bioinformatics workflow but you’re not quite sure how to use it? In this webinar we will introduce the power of Galaxy for construction and (re)use of reproducible workflows, whether building workflows from scratch, recreating them from published descriptions and/or extracting from Galaxy histories. Using an established bioinformatics method, we’ll show you how to: Use the workflows creator in Galaxy Australia Build a workflow based on a published method Annotate workflows so that you (and others) can understand them Make workflows finable and citable (important and very easy to do!) Materials are shared under a Creative Commons Attribution 4.0 International agreement unless otherwise specified and were current at the time of the event. Files and materials included in this record: Event metadata (PDF): Information about the event including, description, event URL, learning objectives, prerequisites, technical requirements etc. Index of training materials (PDF): List and description of all materials associated with this event including the name, format, location and a brief description of each file. GalaxyWorkflows_Slides (PDF): A PDF copy of the slides presented during the webinar. Materials shared elsewhere: A recording of this webinar is available on the Australian BioCommons YouTube Channel: https://youtu.be/IMkl6p7hkho
CHARACTERIZATION OF THE E3 LIGASE DHECW, A NOVEL MEMBER OF THE DROSOPHILA MELANOGASTER NEDD4 FAMILY
Creators: name: FAJNER, VALENTINA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: Ubiquitination is one of the most abundant and versatile post-translation modifications in eukaryotes, and it plays an important role in many biological processes by affecting protein activity, interactions, localization and stability. E3 ligases (E3s) have a key function as molecular ubiquitin-substrate matchmakers, providing specificity to the reaction, yet little is known about the targets and functions of the majority of E3s. In this thesis, we identified and characterized dHecw, a novel member of the Drosophila melanogaster Nedd4 family of ubiquitin E3s. dHecw is the single ortholog of the human HECT ligases HECW1 and HECW2, which are the less characterized members of the family. We proved that dHecw is a catalytically active enzyme, whose expression is tightly regulated in the central nervous system and in the ovary, and is down-modulated during aging. To investigate dHecw function in vivo, we generated catalytic inactive dHecw and KO fly mutants by CRISPR/Cas9 technology. Both types of mutants are viable in homozygosis but presented signs of neurodegeneration, such as short lifespan, limited motor function and brain tissue vacuolarization. They also showed premature decline in fertility due to germline specific defects in oogenesis, including aberrant number of nurse cells, compound egg chambers and misspecification of additional oocytes. The interactome of dHecw was identified by mass spectrometry analysis and includes several ribonucleoparticles (RNPs) components, including dFmr1, a translational repressor that controls localized mRNA translation in developing fly egg chambers. Interestingly, dfmr1 loss of function flies presented ovarian phenotypes that closely resemble the ones of dHecw mutants and KO flies. We demonstrated that dFmrp is a dHecw substrate in vitro, and we found a genetic interaction among the two proteins. Our investigation of the functional outcome of dFmrp ubiquitination suggests that it does not cause dFmrp degradation but, instead, it impacts on its function/interaction network. Indeed, we found that the expression of Orb, a known target of dFmrp repression, is upregulated in dHecw fly mutants. On the contrary, Orb levels are down-modulated upon dHecw overexpression in the germline tissue. Altogether, our data suggest that dHecw is a novel player involved in the dynamic regulation of RNPs required for neuronal health and fertility.
Astrophysical constraints on Planck scale dissipative phenomena
Creators: name: Liberati, Stefano
name: Maccione, Luca
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The emergence of a classical spacetime from any quantum gravity model is still a subtle and only partially understood issue. If indeed spacetime is arising as some sort of large scale condensate of more fundamental objects then it is natural to expect that matter, being a collective excitations of the spacetime constituents, will present modified kinematics at sufficiently high energies. We consider here the phenomenology of the dissipative effects necessarily arising in such a picture. Adopting dissipative hydrodynamics as a general framework for the description of the energy exchange between collective excitations and the spacetime fundamental degrees of freedom, we discuss how rates of energy loss for elementary particles can be derived from dispersion relations and used to provide strong constraints on the base of current astrophysical observations of high energy particles.
description: 5 pages, 1 figure. v2: Minor revisions. Accepted for publication in Phys. Rev. Lett
Laser Theory for Optomechanics: Limit Cycles in the Quantum Regime
Creators: name: Lörch, Niels
name: Qian, Jiang
name: Clerk, Aashish
name: Marquardt, Florian
name: Hammerer, Klemens
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Optomechanical systems can exhibit self-sustained limit cycles where the quantum state of the mechanical resonator possesses nonclassical characteristics such as a strongly negative Wigner density, as was shown recently in a numerical study by Qian et al. [Physical Review Letters, 109, 253601 (2012)]. Here we derive a Fokker-Planck equation describing mechanical limit cycles in the quantum regime which correctly reproduces the numerically observed nonclassical features. The derivation starts from the standard optomechanical master equation, and is based on techniques borrowed from the laser theory due to Haake's and Lewenstein. We compare our analytical model with numerical solutions of the master equation based on Monte-Carlo simulations, and find very good agreement over a wide and so far unexplored regime of system parameters. As one main conclusion, we predict negative Wigner functions to be observable even for surprisingly classical parameters, i.e. outside the single-photon strong coupling regime, for strong cavity drive, and rather large limit cycle amplitudes. The general approach taken here provides a natural starting point for further studies of quantum effects in optomechanics.
description: 17 pages, 7 figures