cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
New Concepts in Therapeutic Manipulation of HIV-1 Transcription and Latency: Latency Reversal versus Latency Prevention
Creators: name: Browne, Edward P.
name: Margolis, David M.
name: Lewis, Catherine A.
Publisher: name: MDPI
Year: 2023

description: Antiretroviral therapy (ART) has dramatically improved the prognosis for people living with HIV-1, but a cure remains elusive. The largest barrier to a cure is the presence of a long-lived latent reservoir that persists within a heterogenous mix of cell types and anatomical compartments. Efforts to eradicate the latent reservoir have primarily focused on latency reversal strategies. However, new work has demonstrated that the majority of the long-lived latent reservoir is established near the time of ART initiation, suggesting that it may be possible to pair an intervention with ART initiation to prevent the formation of a sizable fraction of the latent reservoir. Subsequent treatment with latency reversal agents, in combination with immune clearance agents, may then be a more tractable strategy for fully clearing the latent reservoir in people newly initiating ART. Here, we summarize molecular mechanisms of latency establishment and maintenance, ongoing efforts to develop effective latency reversal agents, and newer efforts to design latency prevention agents. An improved understanding of the molecular mechanisms involved in both the establishment and maintenance of latency will aid in the development of new latency prevention and reversal approaches to ultimately eradicate the latent reservoir.
Der Heilige Stuhl und die Abrüstung
Creators: name: Trettner, Heinz
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 8 Nr. 1 (1979): Internationale katholische Zeitschrift Communio, Band 8, Heft 1
Angular dihadron correlations as interplay of elliptic and triangular flows
Creators: name: Eyyubova, G.
name: Korotkikh, V. L.
name: Lokhtin, I. P.
name: Petrushanko, S. V.
name: Snigirev, A. M.
name: Bravina, L. V.
name: Zabrodin, E. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The hybrid model HYDJET++, which combines soft and hard components, is employed for the analysis of dihadron angular correlations measured in PbPb collisions at center-of-mass energy sqrt(s_NN) = 2.76 TeV. The model allows for study both individual contributions and mutual influence of lower flow harmonics, v_2 and v_3, on higher harmonics and dihadron angular correlations. It is shown that the typical structure called ridge in dihadron angular correlations in a broad pseudorapidity range could appear just as interplay of v_2 and v_3. Central, semi-central and semi-peripheral collisions were investigated. Comparison of model results with the experimental data on dihadron angular correlations is presented for different centralities and transverse momenta p_T.
description: Minor corrections to conform to the journal style
Letter from Michael Hamburger to Robin Skelton, February 03, 1966
Creators: name: Hamburger, Michael
Publisher: name: University of Victoria Libraries
Year: 2023
Subjects: subject: Scholars
valueUri: http://id.worldcat.org/fast/1106878
subject: Literature, Modern
valueUri: http://id.worldcat.org/fast/1000172
subject: Novelists, English
valueUri: http://id.worldcat.org/fast/1039718
subject: Authors
valueUri: http://id.worldcat.org/fast/821688
subject: Hamburger, Michael
valueUri: http://id.worldcat.org/fast/51878
subject: Wiccans
valueUri: http://id.worldcat.org/fast/1765210
subject: Critics
valueUri: http://id.worldcat.org/fast/883769
subject: Periodical editors
valueUri: http://id.worldcat.org/fast/1058064
subject: Editors
valueUri: http://id.worldcat.org/fast/902475
subject: Skelton, Robin
valueUri: http://id.worldcat.org/fast/51853
subject: Poets
valueUri: http://id.worldcat.org/fast/1067778
subject: Novelists
valueUri: http://id.worldcat.org/fast/1039684
subject: Translators
valueUri: http://id.worldcat.org/fast/1154833
subject: Authors, English
valueUri: http://id.worldcat.org/fast/821945
subject: Poets, English
valueUri: http://id.worldcat.org/fast/1067870

description: Part of a collection of letters from poet and German-English translator Michael Hamburger to Robin Skelton. Most of the correspondence discusses work of Hamburger’s that might be included in publications put together by Skelton. In this letter Hamburger says that he is sending Skelton the Günter Eich radio play, with dearest wishes that it be returned to him, as it is Hamburger's only copy.
Observational Implications of OJ 287’s Predicted 2022 Disk Impact in the Black Hole Binary Model
Creators: name: Gupta, Alok C.
name: Valtonen, Mauri J.
name: Imazawa, Ryo
name: Mugrauer, Markus
name: Štrobl, Jan
name: Gomez, Jose L.
name: Uemura, Makoto
name: Pursimo, Tapio
name: Matsumoto, Katsura
name: Berdyugin, Andrei V.
name: Jelínek, Martin
name: Knudstrup, Emil
name: Ciprini, Stefano
name: Gopakumar, Achamveedu
name: Sadun, Alberto
name: Zejmo, Michal
name: Tornikoski, Merja
name: Drozdz, Marek
name: Hudec, Rene
name: Nilsson, Kari
name: Dey, Lankeswar
name: Lehto, Harry J.
name: Reichart, Daniel E.
name: Lähteenmäki, Anne
name: Zola, Staszek
name: Sillanpää, Aimo
name: Kouprianov, Vladimir V.
Publisher: name: MDPI
Year: 2023

description: We present a summary of the results of the OJ 287 observational campaign, which was carried out during the 2021/2022 observational season. This season is special in the binary model because the major axis of the precessing binary happens to lie almost exactly in the plane of the accretion disc of the primary. This leads to pairs of almost identical impacts between the secondary black hole and the accretion disk in 2005 and 2022. In 2005, a special flare called “blue flash” was observed 35 days after the disk impact, which should have also been verifiable in 2022. We did observe a similar flash and were able to obtain more details of its properties. We describe this in the framework of expanding cloud models. In addition, we were able to identify the flare arising exactly at the time of the disc crossing from its photo-polarimetric and gamma-ray properties. This is an important identification, as it directly confirms the orbit model. Moreover, we saw a huge flare that lasted only one day. We may understand this as the lighting up of the jet of the secondary black hole when its Roche lobe is suddenly flooded by the gas from the primary disk. Therefore, this may be the first time we directly observed the secondary black hole in the OJ 287 binary system.
Measurement of Spin Correlation in Top-Antitop Quark Events and Search for Top Squark Pair Production in pp Collisions at $\sqrt{s}=8$ TeV Using the ATLAS Detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A measurement of spin correlation in $t\bar{t}$ production is presented using data collected with the ATLAS detector at the Large Hadron Collider in proton-proton collisions at a center-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 20.3 fb$^{-1}$. The correlation between the top and antitop quark spins is extracted from dilepton $t\bar{t}$ events by using the difference in azimuthal angle between the two charged leptons in the laboratory frame. In the helicity basis the measured degree of correlation corresponds to $A_{helicity} = 0.38 \pm 0.04$, in agreement with the Standard Model prediction. A search is performed for pair production of top squarks with masses close to the top quark mass decaying to predominantly right-handed top quarks and a light neutralino, the lightest supersymmetric particle. Top squarks with masses between the top quark mass and 191 GeV are excluded at the 95% confidence level.
description: 7 pages plus author list + cover pages (20 pages total), 2 figures, 2 tables, submitted to PRL, All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/TOPQ-2014-07/
Statistical inference for Gumbel Type-II distribution under simple step-stress life test using Type-II censoring
Creators: name: Dutta, Subhankar
name: Sultana, Farha
name: Kayal, Suchandan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences
subject: 62N02, 62F10, 62F15

description: In this paper, we focus on the parametric inference based on the Tampered Random Variable (TRV) model for simple step-stress life testing (SSLT) using Type-II censored data. The baseline lifetime of the experimental units, under normal stress conditions, follows the Gumbel Type-II distribution with $α$ and $λ$ being the shape and scale parameters, respectively. Maximum likelihood estimator (MLE) and Bayes estimator of the model parameters are derived based on Type-II censored samples. We obtain asymptotic intervals of the unknown parameters using the observed Fisher information matrix. Bayes estimators are obtained using Markov Chain Monte Carlo (MCMC) method under squared error loss and LINEX loss functions. We also construct highest posterior density (HPD) intervals of the unknown model parameters. Extensive simulation studies are performed to investigate the finite sample properties of the proposed estimators. Three different optimality criteria have been considered to determine the optimal censoring plans. Finally, the methods are illustrated with the analysis of two real data sets.
Spatiotemporal information conversion machine for time-series prediction
Creators: name: Peng, Hao
name: Chen, Pei
name: Liu, Rui
name: Chen, Luonan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Artificial Intelligence (cs.AI)
subject: Dynamical Systems (math.DS)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: I.2.1

description: Making predictions in a robust way is a difficult task only based on the observed data of a nonlinear system. In this work, a neural network computing framework, the spatiotemporal information conversion machine (STICM), was developed to efficiently and accurately render a multistep-ahead prediction of a time series by employing a spatial-temporal information (STI) transformation. STICM combines the advantages of both the STI equation and the temporal convolutional network, which maps the high-dimensional/spatial data to the future temporal values of a target variable, thus naturally providing the prediction of the target variable. From the observed variables, the STICM also infers the causal factors of the target variable in the sense of Granger causality, which are in turn selected as effective spatial information to improve the prediction robustness of time-series. The STICM was successfully applied to both benchmark systems and real-world datasets, all of which show superior and robust performance in multistep-ahead prediction, even when the data were perturbed by noise. From both theoretical and computational viewpoints, the STICM has great potential in practical applications in artificial intelligence (AI) or as a model-free method based only on the observed data, and also opens a new way to explore the observed high-dimensional data in a dynamical manner for machine learning.
description: 28 pages, 6 figures
Politics, policies, and patient care: Rehabilitation therapists' experiences during the COVID-19 Pandemic
Creators: name: Feinberg, Raiya
name: Chowdhury, Ramis
name: Vaughn, Rachel M.
name: Cassidy, Jessica M.
name: Bagatell, Nancy
name: McGovern, Heather
name: Hendry, Katherine
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2023

description: The year 2020 represents a historically turbulent period for the United States marked by the COVID-19 pandemic, a contentious political season, and heightened awareness of racism among citizens. This intersection of medicine, politics, and social unrest generated a demanding clinical environment for healthcare workers, including understudied groups such as physical therapists, occupational therapists, and speech-language pathologists. This descriptive qualitative study focused on experiences and perspectives of clinical rehabilitation therapists working in inpatient rehabilitation and acute-care units from September to November, 2020. Thirteen participants completed individual, semi-structured interviews focused on clinical practice and coping strategies. The analysis included a multi-step, inductive process. Four interconnecting factors chronicling participants' experiences emerged: sociopolitical, institutional, hospital unit, and personal. Stressors and buffers were noted that further shaped individual experiences. Utilization of an ecological framework provided a way to recognize the impact of a complex range of social and environmental factors affecting participants' experiences on personal and professional levels. Awareness of rehabilitation therapists' experiences enriches understanding of the pandemic's effect on healthcare workers and presents clinical implications for healthcare systems to promote therapist well-being.
Assessment of Saccadic Velocity at the Bedside
Creators: name: Ling, Melvin L. H.
name: Tynan, Dominique
name: Ruan, Claire W.
name: Lau, Fiona S.
name: Spencer, Sascha K. R.
name: Agar, Ashish
name: Francis, Ian C.
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Hematology

description: Saccades are a key component for the assessment and diagnosis of Neuro-ophthalmological disorders. Traditionally, clinicians have been taught to use large amplitude saccades (LAS) to assess saccadic velocity (SV), when small amplitude saccades (SAS) may be more effective. This study aimed to evaluate the advantages of SAS over LAS by presenting a video to 108 clinicians where both methods were used to assess a patient with a unilateral partial 6th nerve palsy. SAS was the preferred method in identifying the 6th nerve palsy by 43/55 (78.2%) of Neurologists, and 36/53 (67.9%) of Ophthalmologists. These findings indicate that SAS may be a more effective method than LAS for determining SV.
Projective filtering of a single spatial radiation eigenmode
Creators: name: Pérez, A. M.
name: Sharapova, P. R.
name: Straupe, S. S.
name: Miatto, F. M.
name: Tikhonova, O. V.
name: Leuchs, G.
name: Chekhova, M. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Lossless filtering of a single coherent (Schmidt) mode from spatially multimode radiation is a problem crucial for optics in general and for quantum optics in particular. It becomes especially important in the case of nonclassical light that is fragile to optical losses. An example is bright squeezed vacuum generated via high-gain parametric down conversion or four-wave mixing. Its highly multiphoton and multimode structure offers a huge increase in the information capacity provided that each mode can be addressed separately. However, the nonclassical signature of bright squeezed vacuum, photon-number correlations, are highly susceptible to losses. Here we demonstrate lossless filtering of a single spatial Schmidt mode by projecting the spatial spectrum of bright squeezed vacuum on the eigenmode of a single-mode fiber. Moreover, we show that the first Schmidt mode can be captured by simply maximizing the fiber-coupled intensity. Importantly, the projection operation does not affect the targeted mode and leaves it usable for further applications.
description: 10 pages, 9 figures
Additional file 1 of Physicians’ legal knowledge of informed consent and confidentiality. A cross-sectional study
Creators: name: Plaiasu, Maria Cristina
name: Alexandru, Dragos Ovidiu
name: Nanu, Codrut Andrei
Publisher: name: figshare
Year: 2022
Subjects: subject: Law
subject: FOS: Law

description: Additional file 1. Questionnaire on informed consent and confidentiality.
Localized magnetic plasmons in all-dielectric mu<0 metastructures
Creators: name: Paniagua-Dominguez, R.
name: Froufe-Perez, L. S.
name: Saenz, J. J.
name: Sanchez-Gil, J. A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Metamaterials are known to exhibit a variety of electromagnetic properties non-existing in nature. We show that an all-dielectric (non-magnetic) system consisting of deep subwavelength, high permittivity resonant spheres possess effective negative magnetic permeability (dielectric permittivity being positive and small). Due to the symmetry of the electromagnetic wave equations in classical electrodynamics, localized "magnetic" plasmon resonances can be excited in a metasphere made of such metamaterial. This is theoretically demonstrated by the coupled-dipole approximation and numerically for real spheres, in full agreement with the exact analytical solution for the scattering process by the same metasphere with effective material properties predicted by effective medium theory. The emergence of this phenomenon as a function of structural order within the metastructures is also studied. Universal conditions enabling effective negative magnetic permeability relate subwavelength sphere permittivity and size with critical filling fraction. Our proposal paves the way towards (all-dielectric) magnetic plasmonics, with a wealth of fascinating applications.
description: 7 pages, 4 figures; figure 3 modified and new figure (4) added, with corresponding discussion
Der Christus der Philosophen und das Problem einer philosophischen Christologie
Creators: name: Tilliette, Xavier
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 8 Nr. 1 (1979): Internationale katholische Zeitschrift Communio, Band 8, Heft 1
Band structure of helimagnons in MnSi resolved by inelastic neutron scattering
Creators: name: Kugler, M.
name: Brandl, G.
name: Waizner, J.
name: Janoschek, M.
name: Georgii, R.
name: Bauer, A.
name: Seemann, K.
name: Rosch, A.
name: Pfleiderer, C.
name: Böni, P.
name: Garst, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: A magnetic helix realizes a one-dimensional magnetic crystal with a period given by the pitch length $λ_h$. Its spin-wave excitations -- the helimagnons -- experience Bragg scattering off this periodicity leading to gaps in the spectrum that inhibit their propagation along the pitch direction. Using high-resolution inelastic neutron scattering the resulting band structure of helimagnons was resolved by preparing a single crystal of MnSi in a single magnetic-helix domain. At least five helimagnon bands could be identified that cover the crossover from flat bands at low energies with helimagnons basically localized along the pitch direction to dispersing bands at higher energies. In the low-energy limit, we find the helimagnon spectrum to be determined by a universal, parameter-free theory. Taking into account corrections to this low-energy theory, quantitative agreement is obtained in the entire energy range studied with the help of a single fitting parameter.
description: 5 pages, 3 figures; (v2) slight modifications, published version
Das Selbstbewußtsein Jesu
Creators: name: Balthasar, Hans Urs Von
Publisher: name: Internationale katholische Zeitschrift Communio
Year: 2022

description: Internationale katholische Zeitschrift Communio, Bd. 8 Nr. 1 (1979): Internationale katholische Zeitschrift Communio, Band 8, Heft 1
Additional file 2 of Warmer environmental temperature accelerates aging in mosquitoes, decreasing longevity and worsening infection outcomes
Creators: name: Barr, Jordyn S.
name: Martin, Lindsay E.
name: Tate, Ann T.
name: Hillyer, Julián F.
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Zoology

description: Additional file 2: Table S1. Cox nonproportional hazards with weighted estimation statistical information for Figure 3. Table S2 Median survival and maximum lifespan summary table. Table S3 Cox nonproportional hazards with weighted estimation (stratified by immune treatment) statistical information for Figure 4. Table S4 Zero-inflated negative binomial regression model statistical information for Figure 5.
Additional file 2 of Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression
Creators: name: Kawabe, Akio
name: Yamagata, Kaoru
name: Kato, Shigeaki
name: Nakano, Kazuhisa
name: Sakata, Kei
name: Tsukada, Yu-ichi
name: Ohmura, Koichiro
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Additional file 2: Supplementary Table S1. TET3-mediated upregulated genes. Supplementary Table S2. TET3-mediated downregulated genes. Supplementary Table S3. Results of functional enrichment analysis. Supplementary Table S4. KEGG pathway analysis. Supplementary Table S5. Demographic, clinical, and biochemical features of RA and OA patients whose synovial tissues were used in the experiments.
Population dynamics of immunological synapse formation induced by bispecific T cell engagers predict clinical pharmacodynamics and treatment resistance
Creators: name: Cao, Yanguang
name: Zhou, Jiawei
name: Kudlacek, Stephan
name: Liu, Can
name: Dunlap, Tyler
name: Qi, Timothy
Publisher: name: eLife
Year: 2023

description: Effector T cells need to form immunological synapses (IS) with recognized target cells to elicit cytolytic effects. Facilitating IS formation is the principal pharmacological action of most T cell-based cancer immunotherapies. However, the dynamics of IS formation at the cell population level, the primary driver of the pharmacodynamics of many cancer immunotherapies, remains poorly defined. Using classic immunotherapy CD3/CD19 bispecific T cell engager (BiTE) as our model system, we integrate experimental and theoretical approaches to investigate the population dynamics of IS formation and their relevance to clinical pharmacodynamics and treatment resistance. Our models produce experimentally consistent predictions when defining IS formation as a series of spatiotemporally coordinated events driven by molecular and cellular interactions. The models predict tumor-killing pharmacodynamics in patients and reveal trajectories of tumor evolution across anatomical sites under BiTE immunotherapy. Our models highlight the bone marrow as a potential sanctuary site permitting tumor evolution and antigen escape. The models also suggest that optimal dosing regimens are a function of tumor growth, CD19 expression, and patient T cell abundance, which confer adequate tumor control with reduced disease evolution. This work has implications for developing more effective T cell-based cancer immunotherapies.
Weak measurements of trajectories in quantum systems: classical, Bohmian and sum over paths
Creators: name: Matzkin, Alex
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Weak values, obtained from weak measurements, attempt to describe the properties of a quantum system as it evolves from an initial to a final state, without practically altering this evolution. Trajectories can be defined from weak measurements of the position, or inferred from weak values of the momentum operator. The former can be connected to the asymptotic form of the Feynman propagator and the latter to Bohmian trajectories. Employing a time-dependent oscillator as a model, this work analyzes to what extent weak measurements can shed light on the underlying dynamics of a quantum system expressed in terms of trajectories, in particular by comparing the two approaches.
description: v2:minor changes (typos corrected, some points clarified, extended bibliography). Similar to the published version
Race and sex differences in dropout from the STRRIDE trials
Creators: name: Smith P.J.
name: Siegler I.C.
name: Huffman K.M.
name: Wolever R.Q.
name: Jakicic J.M.
name: Costa P.T.
name: Ross L.M.
name: Collins K.A.
name: Kraus W.E.
Publisher: name: Frontiers Media SA
Year: 2023

description: Purpose: To determine if race and sex differences exist in determinants and timing of dropout among individuals enrolled in an exercise and/or caloric restriction intervention. Methods: A total of 947 adults with dyslipidemia (STRRIDE I, STRRIDE AT/RT) or prediabetes (STRRIDE-PD) were randomized to either inactive control or to 1 of 10 exercise interventions, ranging from doses of 8–23 kcal/kg/week, intensities of 50%–75% (Formula presented.) peak, and durations of 6–8 months. Two groups included resistance training, and one included a dietary intervention (7% weight loss goal). Dropout was defined as an individual withdrawn from the study, with the reasons for dropout aggregated into determinant categories. Timing of dropout was defined as the last session attended and aggregated into phases (i.e., “ramp” period to allow gradual adaptation to exercise prescription). Utilizing descriptive statistics, percentages were generated according to categories of determinants and timing of dropout to describe the proportion of individuals who fell within each category. Results: Black men and women were more likely to be lost to follow-up (Black men: 31.3% and Black women: 19.6%), or dropout due to work responsibilities (15.6% and 12.5%), “change of mind” (12.5% and 8.9%), transportation issues (6.3% and 3.6%), or reported lack of motivation (6.3% and 3.6%). Women in general noted lack of time more often than men as a reason for dropout (White women: 22.4% and Black women: 22.1%). Regardless of race and sex, most participants dropped out during the ramp period of the exercise intervention; with Black women (50%) and White men (37.1%) having the highest dropout rate during this period. Conclusion: These findings emphasize the importance of targeted retention strategies when aiming to address race and sex differences that exist in determinants and timing of dropout among individuals enrolled in an exercise and/or caloric restriction intervention.
Probing Compressed Sleptons at the LHC using Vector Boson Fusion Processes
Creators: name: Dutta, Bhaskar
name: Ghosh, Tathagata
name: Gurrola, Alfredo
name: Johns, Will
name: Kamon, Teruki
name: Sheldon, Paul
name: Sinha, Kuver
name: Wang, Kechen
name: Wu, Sean
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The vector boson fusion (VBF) topology at the Large Hadron Collider at 14 TeV provides an opportunity to search for new physics. A feasibility study for the search of sleptons in a compressed mass spectra scenario is presented in the final state of two jets, one or two low $p_{T}$ non-resonant leptons, and missing energy. The presence of the VBF tagged jets and missing energy are effective in reducing Standard Model backgrounds. Using smuon production with a mass difference between $\tilde{l}_{L}$ and $\tildeχ_{1}^0$ of 5-15 GeV, the significance of observing the signal events is found to be $\sim$ 3-6$σ$ for $m_{\tilde{l}}$=115-135 GeV, considering an integrated luminosity of 3000 fb$^{-1}$.
description: 6 pages, 1 figure, 3 tables; v3: Journal matched version
Long-lived excitons in GaN/AlN nanowire heterostructures
Creators: name: Beeler, M.
name: Lim, C. B.
name: Hille, P.
name: Bleuse, J.
name: Schörmann, J.
name: de la Mata, M.
name: Arbiol, J.
name: Eickhoff, M.
name: Monroy, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: GaN/AlN nanowire heterostructures can display photoluminescence (PL) decay times on the order of microseconds that persist up to room temperature. Doping the GaN nanodisk insertions with Ge can reduce these PL decay times by two orders of magnitude. These phenomena are explained by the three-dimensional electric field distribution within the GaN nanodisks, which has an axial component in the range of a few MV/cm associated to the spontaneous and piezoelectric polarization, and a radial piezoelectric contribution associated to the shear components of the lattice strain. At low dopant concentrations, a large electron-hole separation in both the axial and radial directions is present. The relatively weak radial electric fields, which are about one order of magnitude smaller than the axial fields, are rapidly screened by doping. This bidirectional screening leads to a radial and axial centralization of the hole underneath the electron, and consequently, to large decreases in PL decay times, in addition to luminescence blue shifts.
Additional file 1 of Implementing peer support into practice in mental health services: a qualitative comparative case study
Creators: name: Gillard, Steve
name: Foster, Rhiannon
name: White, Sarah
name: Bhattacharya, Rahul
name: Binfield, Paul
name: Eborall, Rachel
name: Gibson, Sarah L
name: Harnett, Daniella
name: Simpson, Alan
name: Lucock, Mike
name: Marks, Jacqueline
name: Repper, Julie
name: Rinaldi, Miles
name: Salla, Anthony
name: Worner, Jessica
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Supplementary Material 1
Relationships between internalized stigma and depression and suicide risk among queer youth in the United States: a systematic review and meta-analysis
Creators: name: Dawes, Hayden C.
name: Srivastava, Ankur
name: Chen, Wan-Ting
name: Hall, William J.
name: Bouchard, D.
name: Williams, Denise Yookong
name: Ramon, Magdelene
name: Radtke, Spenser R.
name: Goldbach, Jeremy T.
Publisher: name: Frontiers Media SA
Year: 2023

description: Background Queer youth experience high rates of depression and suicidality. These disparities stem from stigma-based stressors, including internalized stigma (i.e., negative social views that minoritized individuals internalize about their own identity). Given the importance of this factor in understanding mental health disparities among queer youth, we completed a systematic review and meta-analysis examining the relationships between internalized stigma and outcomes of depression and suicide risk (i.e., suicidal ideation, non-suicidal self-injury, and suicidal behavior). Methods We followed the PRISMA standards. Six bibliographic databases were searched for studies in the United States from September 2008 to March 2022. Dual independent screening of search results was performed based on a priori inclusion criteria. Results A total of 22 studies were included for data extraction and review. Most studies examined general internalized homophobia, with few examining internalized biphobia or transphobia. Many studies examined depression as an outcome, few studies examined suicidal ideation or behavior, and no studies examined non-suicidal self-injury. Meta-analyses model results show the association between general internalized queer stigma and depressive symptoms ranged r = 0.19, 95% CI [0.14, 0.25] to r = 0.24, 95% CI [0.19, 0.29], the latter reflecting more uniform measures of depression. The association between internalized transphobia and depressive outcomes was small and positive (r = 0.21, 95% CI [−0.24, 0.67]). General internalized queer stigma and suicidal ideation had a very weak positive association (r = 0.07, 95% CI [−0.27, 0.41]) and an even smaller, weaker positive association with suicide attempt (r = 0.02, 95% CI [0.01, 0.03]). Conclusion Implications for clinical practice, policy, and future research are discussed.
Project INDIGO - document, disseminate & analyse a graffiti-scape
Creators: name: Wild, Benjamin
name: Verhoeven, Geert Julien
name: Schlegel, Jona
name: Wieser, Martin
name: Pfeifer, Norbert
name: Wogrin, Stefan
name: Eysn, Lothar
name: Carloni, Massimiliano
name: Koschiček-Krombholz, Bernhard
name: Molada-Tebar, Adolfo
name: Otepka-Schremmer, Johannes
name: Ressl, Camillo
name: Trognitz, Martina
name: Watzinger, Alexander
Publisher: name: Zenodo
Year: 2022
Subjects: Austria
cultural heritage
graffiti
graffiti-scape
heritage science
IBM (Image-Based Modelling)
INDIGO
laser scanning
mobile laser scanning
PCV (Photogrammetric Computer Vision)
photography
SfM (Structure from Motion)
Street art
Vienna

description: This presentation was given by Benjamin Wild at the 3D-ARCH 2022 conference in Mantova, Italy. The presentation won the best paper award.
description: The INDIGO graffiti project is funded by the Heritage Science Austria programme of the Austrian Academy of Sciences (ÖAW)
Additional file 3 of Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression
Creators: name: Kawabe, Akio
name: Yamagata, Kaoru
name: Kato, Shigeaki
name: Nakano, Kazuhisa
name: Sakata, Kei
name: Tsukada, Yu-ichi
name: Ohmura, Koichiro
name: Nakayamada, Shingo
name: Tanaka, Yoshiya
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Additional file 3.
Self-Compassion and Depressive Symptoms as Determinants of Sensitive Parenting: Associations with Sociodemographic Characteristics in a Sample of Mothers and Toddlers
Creators: name: Zvara, Bharathi J.
name: Andridge, Rebecca
name: Keim, Sarah A.
name: Anderson, Sarah E.
Publisher: name: MDPI
Year: 2023

description: Parenting that is sensitive and responsive to children’s needs has been shown to support children’s optimal growth and development in many cultural contexts. Numerous studies suggest that self-compassion is positively related to sensitive parenting. Despite growing research interest linking self-compassion to responsive parenting, there are considerable gaps in the literature. The current study examined the associations between self-compassion, depressive symptoms, socioeconomic status, and sensitive parenting. Data was obtained from a cohort study of 300 families in central Ohio enrolled when children were a mean (SD) calendar age of 18.2 (0.7) months. Children of all gestational ages at birth are included, and 37% were born preterm (<37 weeks’ gestation). Observational protocols were used to determine maternal sensitivity in a semi-structured play setting. Self-compassion was assessed with the Self-Compassion Scale when children were 24 months old. Self-compassion was not associated with sociodemographic characteristics including maternal education, household income, child sex and gestational age. In unadjusted regression models, depressive symptoms were related to sensitive parenting (B = −0.036, SE = 0.016, p = 0.03), but self-compassion was not a statistically significant predictor (p = 0.35) of sensitivity, and neither self-compassion nor depressive symptoms were statistically significant predictors of sensitive parenting after adjustment for covariates. Considerations for future studies are discussed.
The APC-EPCR-PAR1 axis in sickle cell disease
Creators: name: Ramadas N.
name: Sparkenbaugh E.M.
Publisher: name: Frontiers Media SA
Year: 2023

description: Sickle Cell Disease (SCD) is a group of inherited hemoglobinopathies. Sickle cell anemia (SCA) is caused by a homozygous mutation in the β-globin generating sickle hemoglobin (HbS). Deoxygenation leads to pathologic polymerization of HbS and sickling of erythrocytes. The two predominant pathologies of SCD are hemolytic anemia and vaso-occlusive episodes (VOE), along with sequelae of complications including acute chest syndrome, hepatopathy, nephropathy, pulmonary hypertension, venous thromboembolism, and stroke. SCD is associated with endothelial activation due to the release of danger-associated molecular patterns (DAMPs) such as heme, recurrent ischemia–reperfusion injury, and chronic thrombin generation and inflammation. Endothelial cell activation is mediated, in part, by thrombin-dependent activation of protease-activated receptor 1 (PAR1), a G protein coupled receptor that plays a role in platelet activation, endothelial permeability, inflammation, and cytotoxicity. PAR1 can also be activated by activated protein C (APC), which promotes endothelial barrier protection and cytoprotective signaling. Notably, the APC system is dysregulated in SCD. This mini-review will discuss activation of PAR1 by APC and thrombin, the APC-EPCR-PAR1 axis, and their potential roles in SCD.
Analytic Structure of the S-Matrix for Singular Quantum Mechanics
Creators: name: Camblong, Horacio E.
name: Epele, Luis N.
name: Fanchiotti, Huner
name: Canal, Carlos A. Garcia
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The analytic structure of the S-matrix of singular quantum mechanics is examined within a multichannel framework, with primary focus on its dependence with respect to a parameter ($Ω$) that determines the boundary conditions. Specifically, a characterization is given in terms of salient mathematical and physical properties governing its behavior. These properties involve unitarity and associated current-conserving Wronskian relations, time-reversal invariance, and Blaschke factorization. The approach leads to an interpretation of effective nonunitary solutions in singular quantum mechanics and their determination from the unitary family.
description: 14 pages, 1 figure
Additional file 1 of 2,4-Dichlorophenol biotransformation using immobilized marine halophilic Bacillus subtilis culture and laccase enzyme: application in wastewater treatment
Creators: name: Farag, Aida M.
name: El-Naggar, Moustafa Y.
name: Ghanem, Khaled M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Supplementary Figure 1. Gamma hemolysis of Bacillus subtilis AAK (did not shown any hemolytic activity) against blood in the blood agar medium.
Measurements of differential and double-differential Drell-Yan cross sections in proton-proton collisions at 8 TeV
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Measurements of the differential and double-differential Drell-Yan cross sections in the dielectron and dimuon channels are presented. They are based on proton-proton collision data at sqrt(s) = 8 TeV recorded with the CMS detector at the LHC and corresponding to an integrated luminosity of 19.7 inverse femtobarns. The measured inclusive cross section in the Z peak region (60-120 GeV), obtained from the combination of the dielectron and dimuon channels, is 1138 +/- 8 (exp) +/- 25 (theo) +/- 30 (lumi) pb, where the statistical uncertainty is negligible. The differential cross section d(sigma)/d(m) in the dilepton mass range 15 to 2000 GeV is measured and corrected to the full phase space. The double-differential cross section d2(sigma)/d(m)d(abs(y)) is also measured over the mass range 20 to 1500 GeV and absolute dilepton rapidity from 0 to 2.4. In addition, the ratios of the normalized differential cross sections measured at sqrt(s) = 7 and 8 TeV are presented. These measurements are compared to the predictions of perturbative QCD at next-to-leading and next-to-next-to-leading (NNLO) orders using various sets of parton distribution functions (PDFs). The results agree with the NNLO theoretical predictions computed with FEWZ 3.1 using the CT10 NNLO and NNPDF2.1 NNLO PDFs. The measured double-differential cross section and ratio of normalized differential cross sections are sufficiently precise to constrain the proton PDFs.
description: Replaced with published version. Added journal reference and DOI
The co-management of HIV and chronic non-communicable diseases in the Dominican Republic: A qualitative study
Creators: name: Wallace, Deshira D.
name: Paulino, Gipsy Jiménez
name: Castro, Stephanie Daniela
name: Palar, Kartika
name: Then-Paulino, Amarilis
name: Castro, Flabia Tejada
name: Derose, Kathryn P.
Publisher: name: Public Library of Science
Year: 2023

description: People living with HIV and a non-communicable disease (NCD) experience multi-level barriers when co-managing multiple conditions. We explored the factors affecting living with multiple chronic conditions in the Dominican Republic. We conducted 21 in-depth interviews from October 2019-February 2020 with Dominican adults who participated in a food security intervention and managed HIV and at least one chronic NCD. Using thematic analysis, we explored participant lived experiences co-managing multiple chronic conditions. All participants (mean age = 45.5 years) were linked to HIV care, but only three were linked to NCD-specific care. Individual-level barriers to managing NCDs included limited education and limited self-efficacy for self-management. Interpersonally, barriers included limited rapport building with an NCD-specific specialist. Structural barriers to managing NCDs were no health insurance, poor referral systems, and limited financial assistance. Health system adaptation requires equitably considering the needs of individuals managing multiple chronic conditions. Key factors to address include patient-provider relationships, improved referral systems, accessibility and availability of specialists, and financial assistance.
Additional file 2 of Investigation of foot and mouth disease virus and other animal pathogens in cattle, buffaloes and goats at the interface with Akagera National Park 2017 – 2020
Creators: name: Udahemuka, Jean Claude
name: Aboge, Gabriel
name: Obiero, George
name: Ingabire, Angélique
name: Beeton, Natasha
name: Uwibambe, Evodie
name: Lebea, Phiyani
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 2. FMD serological NSP results from cattle and goats in Eastern Rwanda.
Zeitenwende und Endzeitfieber
Creators: name: Rausch, Ulrich
name: Grabner-Haider, Anton
name: Schachl-Raber, Ursula
Publisher: name: Diakonia
Year: 1970

description: Diakonia, Bd. 30 Nr. 6 (1999): Diakonia, Band 30, Heft 6
Additional file 2 of Exploring the perspectives of health care professionals on digital health technologies in pediatric care and rehabilitation
Creators: name: Roy, Isabelle
name: Salles, Julia
name: Neveu, Erika
name: Lariviére-Bastien, Danaë
name: Blondin, Aurélie
name: Levac, Danielle
name: Beauchamp, Miriam H.
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Biological Sciences not elsewhere classified
Science Policy

description: Additional file 2: Table S1: Demographic characteristics and digital health technology use among participants
The Current Landscape of Glioblastoma Biomarkers in Body Fluids
Creators: name: Farjadian, Fatemeh
name: Benhabbour, Soumya Rahima
name: Doroudian, Mohammad
name: Zanganeh, Saba
name: Esmaelizad, Nazanin
name: Abbasgholinejad, Elham
Publisher: name: MDPI
Year: 2023

description: Glioblastoma (GBM) is a highly aggressive and lethal primary brain cancer that necessitates early detection and accurate diagnosis for effective treatment and improved patient outcomes. Traditional diagnostic methods, such as imaging techniques and tissue biopsies, have limitations in providing real-time information and distinguishing treatment-related changes from tumor progression. Liquid biopsies, used to analyze biomarkers in body fluids, offer a non-invasive and dynamic approach to detecting and monitoring GBM. This article provides an overview of GBM biomarkers in body fluids, including circulating tumor cells (CTCs), cell-free DNA (cfDNA), cell-free RNA (cfRNA), microRNA (miRNA), and extracellular vesicles. It explores the clinical utility of these biomarkers for GBM detection, monitoring, and prognosis. Challenges and limitations in implementing liquid biopsy strategies in clinical practice are also discussed. The article highlights the potential of liquid biopsies as valuable tools for personalized GBM management but underscores the need for standardized protocols and further research to optimize their clinical utility.
Optical scatter of quantum noise filter cavity optics
Creators: name: Vander-Hyde, Daniel
name: Amra, Claude
name: Lequime, Michel
name: Magaña-Sandoval, Fabian
name: Smith, Joshua R.
name: Zerrad, Myriam
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Optical cavities to filter squeezed light for quantum noise reduction require optics with very low scattering losses. We report on measured light scattering from two super-polished fused silica optics before and after applying highly-reflective ion-beam sputtered dielectric coatings. We used an imaging scatterometer that illuminates the sample with a linearly polarized 1064 nm wavelength laser at a fixed angle of incidence and records images of back scatter for azimuthal angles in the plane of the laser beam. We extract from these images the bidirectional reflectance distribution function (BRDF) of the optics with and without coating and estimate their integrated scatter. We find that application of these coatings led to a more than 50% increase of the integrated wide-angle scatter, to 5.00+/-0.30 and 3.38+/-0.20 ppm for the two coated samples. In addition, the BRDF function of the coated optics takes on a pattern of maxima versus azimuthal angle. We compare with a scattering model to show that this is qualitatively consistent with roughness scattering from the coating layer interfaces. These results are part of a broader study to understand and minimize optical loss in quantum noise filter cavities for interferometric gravitational-wave detectors. The scattering measured for these samples is acceptable for the 16 m long filter cavities envisioned for the Laser Interferometer Gravitational-wave Observatory (LIGO), though reducing the loss further would improve LIGO's quantum-noise limited performance.
description: 10 pages, 3 figures