cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Plocopsylla (Plocopsylla) wilesi Beaucournu & Kelt 1990
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Stephanocircidae
Plocopsylla
Plocopsylla wilesi

description: Plocopsylla (Plocopsylla) wilesi Beaucournu & Kelt, 1990
FMR (MNHN). Chile—Aisén. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea. Chile; Argentina— Chubut: Carhué Niyeu, Establecimiento La Maroma Alm. Hotel Los Manantiales. Neuquén: Auca Mahuida, Riscos Altos. Río Negro: Campamento PNG Somuncurá, Cerro Corona, Laguna Blanca. Santa Cruz: Pali Aike. Mammalia—Rodentia—Cricetidae— Abrothrix hirta, Abrothrix olivacea, Euneomys chinchilloides, Eligmodontia morgani, Phyllotis xanthopygus. Sanchez & Lareschi (2013), Sanchez et al. (2015).
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 245, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Plocopsylla (Schrammapsylla) wolffsohni Rothschild 1909
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Stephanocircidae
Plocopsylla
Plocopsylla wolffsohni

description: Plocopsylla (Schrammapsylla) wolffsohni (Rothschild, 1909)
NHM. Chile—Valparaíso. Mammalia—Rodentia—Cricetidae— Abrothrix hirta. Chile; Argentina—Neuquén: Cerro Chapelco, Lago Curruhue, Lago Norquinco, Lago Quillen, Laguna Verde, Ruca Malen. Río Negro: San Carlos de Bariloche. Mammalia—Rodentia—Cricetidae— Abrothrix hirta, Abrothrix olivacea, Akodon sp., Euneomys sp., Irenomys tarsalis, Oligoryzomys longicaudatus.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 246, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Garrulaxeus formosus Mey 2017
Creators: name: Gustafsson, Daniel R.
name: Bush, Sarah E.
name: Palma, Ricardo L.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Phthiraptera
Philopteridae
Garrulaxeus
Garrulaxeus formosus

description: Garrulaxeus formosus Mey, 2017
Garrulaxeus formosus Mey, 2017: 163, fig. 86, pl. XV: figs 3–4.
Priceiella (Thescelovora) formosa (Mey, 2017). New combination.
Type host: Ianthocincla poecilorhyncha (Gould, 1863) —rusty laughingthrush.
Type locality: Taiwan.
Remarks. We transfer Garrulaxeus formosus to Priceiella (Thescelovora) based on the shape of the male genitalia illustrated by Mey (2017: fig. 86). The length of the parameres would separate this species from all species of Thescelovora previously known or described by Mey (2017). However, as most other morphological details are unknown, Garrulaxeus formosus is in need of a proper redescription.
description: Published as part of Gustafsson, Daniel R., Bush, Sarah E. & Palma, Ricardo L., 2019, The genera and species of the Brueelia - complex (Phthiraptera: Philopteridae) described by Mey (2017), pp. 252-284 in Zootaxa 4615 (2) on page 273, DOI: 10.11646/zootaxa.4615.2.2, http://zenodo.org/record/3244680
Targeting T Cells to Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The premise of this grant is that recombinant DNA technology can be used to create human immune cells that will target and kill breast cancer. The primary function of the human immune system is to fight infection brought about by viruses and bacteria. The immune system will not normally recognize or attack one’s own tissues. Because cancer is really derived from one’s own tissues, the immune system has difficulty in identifying cancerous cells and often fails in combating this disease.

 We have developed a new protein engineering technique called "protein loop grafting", which allows us to rapidly and precisely change the function of a protein. We plan to use this strategy to alter the function of proteins in the immune system called T-cell receptors. T-cell receptors can actually direct the immune system to attack specific targets. Our strategy is to alter the T-cell receptor so that it can bind to multiple proteins on the surface of breast cancer cells. We will accomplish this by using protein loop grafting. We hypothesize that the immune cells that contain the engineered T-cell receptor will display "targeted immunity". In other words, they will seek out and kill breast cancer cells. If the studies we propose here are successful, they will solve a major problem in cancer and immunity because we will be able to redirect the immune system so that it can recognize and destroy tumors. Once these concepts have been tested in the laboratory, a gene therapy approach can be developed to alter a patient’s own lymphocytes so that they can bind to and kill breast cancer cells. The potential rewards of this ITaMoCA are: the development of an entirely novel way of manipulating the binding function of the T-cell receptors; the creation of the first T-cell receptor with the ability to recognize two separate proteins on the surface of breast cancer cells, an advance that is likely to assist in applying immunotherapy in a tumor-selective manner; and a potential immunotherapy for patients with advanced stage breast carcinoma.
Protease Fingerprinting to Diagnose Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: There is still a great need to develop more convenient, cost effective, and accurate methods of detecting and tracking breast cancer. The availability of simple and rapid blood tests to screen for breast cancer could vastly increase the number women who are routinely screened. A blood test that detects breast cancer could, like cholesterol screening and PSA for prostate cancer, potentially be used to detect disease stage, changes in disease progression, and to monitor therapy. It would be particularly important for high-risk women, breast cancer survivors at risk for recurrence, and younger women who are difficult to screen accurately using mammography. The two hurdles that must be overcome, 1) the test must recognize many parameters, and 2) the test must be highly sensitive.

 This study proposes a method for identifying the "fingerprint" of breast cancer. We plan to study changes in a group of proteins called proteases, which cut other proteins into smaller segments causing them to break down. This tumor-associated proteolytic activity causes the localized changes in the surrounding extracellular matrix, which are key to blood vessel formation (angiogenesis), tumor cell migration, and spread to other parts of the body (metastasis). Our hypothesis is that some of these tumor proteases are released into the blood, and are potentially detectable using emerging technologies. Thus, we will test blood samples from tumor-bearing animals for their ability to cleave peptides that are known substrates for cell proteases. In another phase of the project we will confirm that proteases of interest are associated with the tumor and not originating from other sources. A protease 'fingerprint' would be diagnostic for the clinical parameters associated with breast cancer.

 In this phase of the project, we hope to identify 50+ unique proteases indicating the presence of breast cancer. We also suspect that another 50+ will indicate that a tumor has metastasized, or is capable of metastasizing. We anticipate that the results of this study will point the way for a future test of this approach in human breast cancer patients.
Additional file 4: of A key enzyme of animal steroidogenesis can function in plants enhancing their immunity and accelerating the processes of growth and development
Creators: name: Shpakovski, George
name: Spivak, Svetlana
name: Berdichevets, Irina
name: Babak, Olga
name: Kubrak, Svetlana
name: Kilchevsky, Alexander
name: Aralov, Andrey
name: Slovokhotov, Ivan
name: Shpakovski, Dmitry
name: Baranova, Ekaterina
name: Khaliluev, Marat
name: Shematorova, Elena
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Assessment of fungicidal properties of transgenic tobacco plants. (DOC 28Â kb)
Plocopsylla (Schrammapsylla) chiris
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Stephanocircidae
Plocopsylla
Plocopsylla chiris

description: Plocopsylla (Schrammapsylla) chiris (Jordan, 1931)
NHM. Argentina—Río Negro: Pilcaniyeu. Mammalia—Cricetidae— Phyllotis xanthopygus.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 245, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
SUSTAINABILITY REPORTING IN RWANDA'S BANKING SECTOR: TRENDS AND IMPACTS
Creators: name: 1Mbonigaba Celestin, 2Lemlem Desta & 3Rachid Boudlal, 4Olivia Martinez
Publisher: name: Zenodo
Year: 2012

description: This research investigates the trends and impacts of sustainability reporting in Rwanda’s banking sector, focusing on the period 2005–2012. Utilizing a qualitative methodology, the study integrates secondary data analysis from sustainability reports, policy documents, and semi-structured interviews with industry experts. Statistical tests, including a chi-square test (χ²=14.82, p<0.01) and paired sample t-tests (t=3.94, p<0.01; t=4.27, p<0.01), revealed a significant growth in sustainability reporting adoption and its positive influence on operational performance and stakeholder trust. However, regression analysis identified financial constraints (B=−0.47, p<0.05) and regulatory inconsistencies (B=−0.39, p<0.05) as major challenges, while capacity-building initiatives (B=0.52, p<0.01) emerged as critical enablers. The study concludes that sustainability reporting aligns Rwanda’s banking sector with global ESG standards but requires standardized frameworks, enhanced regulatory mechanisms, and active stakeholder engagement for further advancement. Recommendations include the adoption of international reporting standards, capacity-building initiatives, and external assurance to improve transparency and accountability.
Additional file 6: of Metabolic pathways and genes identified by RNA-seq analysis of barley near-isogenic lines differing by allelic state of the Black lemma and pericarp (Blp) gene
Creators: name: Glagoleva, Anastasiya
name: Shmakov, Nikolay
name: Shoeva, Olesya
name: Vasiliev, Gennady
name: Shatskaya, Natalia
name: Börner, Andreas
name: Afonnikov, Dmitry
name: Khlestkina, Elena
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: The total antioxidant content (mg/g) in grains of Bowman (BW) and BLP lines (equivalent to Gallic acid). Method 1: extracts were prepared by incubation of 1 g of whole grain powder in 10 ml of 1% HCl for 1 h at 37 °C. Method 2: 1 g of whole grain powder was incubated in 10 ml of 1% HCl in 40% ethanol for 30 min at 37 °C. Measurements were performed with the antioxidant activity analyser ‘Blizar’ (Interlab Ltd., Russia) according to the manufacturer’s instructions. * - difference between BW and BLP is significant (p ≤ 0.01; U-test). (PDF 183 kb)
Garrulaxeus parvus Mey 2017
Creators: name: Gustafsson, Daniel R.
name: Bush, Sarah E.
name: Palma, Ricardo L.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Aves
Passeriformes
Neosittidae
Garrulaxeus
Garrulaxeus parvus

description: Garrulaxeus parvus Mey, 2017
Garrulaxeus parvus Mey, 2017: 164, fig. 88, pl. XVI: fig. 1.
Brueelia parva (Mey, 2017). New combination.
Type host: Turdoides gularis (Blyth, 1855) —white-throated babbler.
Type locality: Thityapante, 50 km S of Magwe, Myanmar.
Remarks. Both illustrations of this species given by Mey (2017) show severely distorted male genitalia; this fact, together with a very brief text description and diagnosis, makes it difficult to place G. parvus in any genus. However, the photograph of the male holotype shows that this species would belong in a group with Brueelia pengya (Ansari, 1947), within Brueelia sensu stricto; hence we tentatively place it in that group. This group is also known by the name Painjunirmus Ansari, 1947, and Gustafsson & Bush (2017: 37) regarded it as “atypical” considering that the morphological differences between Painjunirmus and Brueelia sensu stricto may be enough to warrant the recognition of Painjunirmus as a subgenus. In an upcoming publication, Gustafsson & Bush (in prep.) analyse this group in more detail including the comments made by Mey (2017: 155–156).
description: Published as part of Gustafsson, Daniel R., Bush, Sarah E. & Palma, Ricardo L., 2019, The genera and species of the Brueelia - complex (Phthiraptera: Philopteridae) described by Mey (2017), pp. 252-284 in Zootaxa 4615 (2) on page 273, DOI: 10.11646/zootaxa.4615.2.2, http://zenodo.org/record/3244680
Additional file 5: of A key enzyme of animal steroidogenesis can function in plants enhancing their immunity and accelerating the processes of growth and development
Creators: name: Shpakovski, George
name: Spivak, Svetlana
name: Berdichevets, Irina
name: Babak, Olga
name: Kubrak, Svetlana
name: Kilchevsky, Alexander
name: Aralov, Andrey
name: Slovokhotov, Ivan
name: Shpakovski, Dmitry
name: Baranova, Ekaterina
name: Khaliluev, Marat
name: Shematorova, Elena
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Compound racemes with large sepals and undeveloped pistils and stamens of the transgenic line No. 7. (DOC 237Â kb)
Sphinctopsylla ares Rothschild 1911
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Stephanocircidae
Sphinctopsylla
Sphinctopsylla ares

description: Sphinctopsylla ares (Rothschild, 1911)
NHM. Chile—Temuco. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea. Chile; Argentina—Chubut: Cañadón de la Madera, Sierra Tepuel, Ea. Leleque, Lago Blanco. Neuquén: Aguas calientes, Domuyo, Pla. Quetrihué. Río Negro: Bariloche. Santa Cruz: Ea. La Ensenada, Pali Aike. Tierra del Fuego, Antártida e Islas del Atlántico Sur: Margen derecha del Aº Buena Esperanza. Mammalia—Rodentia—Cricetidae— Abrothrix hirta, Abrothix olivacea, Akodon dolores, Euneomys chinchilloides, Geoxus valdivianus, Oligoryzomys longicaudatus, Phyllotis xanthopygus. Muridae— Rattus sp. Sanchez et al. (2009), Sanchez & Lareschi (2013; 2014).
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 246, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Climate change and range expansion of the Asian tiger mosquito (Aedes albopictus) in northeastern USA: implications for public health practitioners
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 2013

description: The Asian tiger mosquito, Aedes albopictus (Skuse), is an invasive species with substantial biting activity, high disease vector potential, and a global distribution that continues to expand. New Jersey, southern New York, and Pennsylvania are currently the northernmost boundary of established Ae. albopictus populations in the eastern United States. Using positive geographic locations from these areas, we modeled the potential future range expansion of Ae. albopictus in northeasternUSA under two climate change scenarios. The land area with environmental conditions suitable for Ae. albopictus populations is expected to increase from the current 5% to 16% in the next two decades and to 43%–49% by the end of the century. Presently, about one-third of the total human population of 55 million in northeastern USA reside in urban areaswhere Ae. albopictus is present. This number is predicted to double to about 60% by the end of the century, encompassingall major urban centers and placing over 30 million people under the threat of dense Ae. albopictus infestations. This mosquito species presents unique challenges to public health agencies and has already strained the resources available to mosquito control programs within its current range. As it continues to expand into areas with fewer resources and limited organized mosquito control, these challenges will be further exacerbated. Anticipating areas of potential establishment,while planning ahead and gathering sufficient resources will be the key for successful public health campaigns. A broad effort in community sanitation and education at all levels of government and the private sector will be required until new control techniques are developed that can be applied efficiently and effectively at reasonable cost to very large areas.
The commercial sex industry in Douala, Cameroon
Creators: name: Asuagbor, Dilys
Publisher: name: No Publisher Supplied
Year: 2014

description: The literature on the commercial sex industry shows that extensive studies of the phenomenon have been undertaken in the United States of America, Europe and Asia. By comparison, relatively little research has investigated commercial sex in the African context, despite evidence that it is widespread in many nations throughout the continent, including the West Central African nation of Cameroon.   Using the qualitative method of inquiry, interviews were conducted with 50 sex workers in Douala, the nation’s economic capital, covering different venues and types of sex work undertaken. The findings illuminate our understanding of: the pathways into prostitution in Douala, the nature and organization of sex work in Douala, and the risks and challenges faced by sex workers in Douala.   The extent of prostitution in Cameroon was not undertaken and remains an opportunity for future research. This research serves as a useful resource for public policy considerations in Cameroon and contributes to the growing body of research on the commercial sex industry in Africa generally and Cameroon specifically. It also provides a strong basis for comparative research with other studies that have been and are currently being undertaken elsewhere.
Additional file 2: of GWAS of agronomic traits in soybean collection included in breeding pool in Kazakhstan
Creators: name: Zatybekov, Alibek
name: Abugalieva, Saule
name: Didorenko, Svetlana
name: Gerasimova, Yelena
name: Sidorik, Ivan
name: Anuarbek, Shynar
name: Turuspekov, Yerlan
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Science Policy
subject: Plant Biology
subject: 60506 Virology

description: The list of total MTAs identified by Tassell 5.0 package. (PDF 184 kb)
Sphinctopsylla mars Rothschild 1898
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Stephanocircidae
Sphinctopsylla
Sphinctopsylla mars

description: Sphinctopsylla mars (Rothschild 1898)
NHM. Argentina—Tierra del Fuego, Antártida e Islas del Atlántico Sur: Ushuaia Bahía, San Sebastian. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea. Argentina—Tierra del Fuego, Antártida e Islas del Atlántico Sur: Ushuaia Bahia, San Sebastián. Mammalia—Rodentia—Cricetidae— Abrothrix olivacea, Calomys sp.
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 246, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Heteranthera Ruiz & Pavon 1794
Creators: name: Carnevali, Germán
name: Stefano, Rodrigo Duno De
name: Ramírez-Morillo, Ivón M.
name: Grande Allende, José R.
name: Barrios, Yeni
name: Tapia-Muñoz, José Luis
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Commelinales
Pontederiaceae
Heteranthera

description: Key to Heteranthera in the Mexican Yucatan Peninsula
1. Leaf-blade clearly differentiated from petiole, variously ovate, elliptical to orbicular; the pseudo-petiole longer than the blade; flowers always purple or purple-violet............................................................................................................... Heteranthera limosa
- Leaf-blade not differentiated from petiole, linear; flowers purple-violet, lilac or yellow..................................................................2
2. Inflorescence sessile, axillary, with a solitary flower; flowers yellow, actinomorphic; all three anthers of the same size and shape. ............................................................................................................................................................................. Heteranthera dubia
- Inflorescence pedunculate, terminal, generally with several flowers, rarely only a single one; flowers lilac, zygomorphic; anthers of different sizes and shapes........................................................................................................................... Heteranthera yucatana
description: Published as part of Carnevali, Germán, Stefano, Rodrigo Duno De, Ramírez-Morillo, Ivón M., Grande Allende, José R., Barrios, Yeni & Tapia-Muñoz, José Luis, 2022, Heteranthera yucatana (Pontederiaceae), a new, threatened species from the Mexican Yucatan Peninsula, pp. 20-30 in Phytotaxa 547 (1) on page 27, DOI: 10.11646/phytotaxa.547.1.2, http://zenodo.org/record/6555750
Role of Chemokine Receptors in Breast Cancer Metastasis
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: We need to understand more about how breast cancer cells become motile, particularly the ways that they enter and leave the lymphatic and blood vessels, which are the critical conduits to spread in the body. White blood cells are capable of moving out of the blood and lymph, and much is known of the specific cell surface proteins and soluble factors that regulate this process. These proteins and receptors are called chemokines. Although there is convincing evidence that chemokines and their cell surface receptors are involved in the growth and metastasis of some human tumors, the exact molecular nature of this involvement has yet to be elucidated. In human breast cancers, spreading to bone marrow and lung is characteristic of late stage disease in a large percentage of patients. In order to better understand this pathogenesis we will study the role of chemokines in breast cancer metastasis using molecular biology techniques and cell motility assays. Our basic premise is that because chemokines turn on the cellular machinery that produces directional migration of many cells, these same molecules may contribute to the metastasis of primary breast tumors.

 To examine the possible presence and function of chemokines and their receptors in breast cancer, we will use new molecular assays (PCR-based), immunological (ELISA) techniques and physiological tools initially developed in our laboratory for the study of leukocytes. Thus, we will: (1) look for the mRNA expression of chemokines and receptors, (2) determine whether chemokine receptors are functionally coupled to calcium signaling pathways involved in breast cancer cell motility, (3) determine whether expressed chemokine receptors stimulate the migration of breast cancer cells, and (4) determine whether any of the breast cancer cell lines secrete chemokines which may function as autocrine (i.e., locally acting) motility factors. This study could uncover an autocrine motility loop, which might explain the basis for increased metastatic potential.

 A real plus to our breast cancer-chemokine survey is that we will make use of a number of new anti-inflammatory and anti-viral chemokine therapeutics currently being developed in immunology research. If chemokine receptors are involved in cancer metastasis, it is quite likely that some of these newly developed drugs would also have anti-metastatic properties. One can envision a potent metastasis inhibitor based on controlling the motility of primary tumors. Such a drug could be a major new tool in the fight against breast cancer.
Superfibronectin: A Novel Anti-Breast Cancer Agent
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The spread of breast cancer to other, distant organs is a process known as metastasis. The most common organs affected by metastasis are bones, lungs, and liver. Metastasis makes breast cancer almost incurable. Early detection and treatment addresses cancer spread indirectly, but no present treatment directly blocks metastasis. In order to spread, the cancer cells break free from the primary tumor, enter the lymph or blood, and leave the circulation at preferred organ sites. This final phase of circulation arrest and escape involves the binding of tumor cell surface receptors to protein components that surround cells, the extracellular matrix (ECM). One component of the ECM is fibrobnectin (FN), a complex protein also present in the blood. Thus, the tumor cells in transit in the blood could be ‘attacked’ and neutralized by therapeutic agents that target their receptors for FN.

 Our approach is to study modified forms of FN to disrupt the process of breast cancer cell adhesion specific for metastasis. We have recently developed a polymer of FN, called superfibronectin (sFN), which can block cell adhesion and migration in the laboratory. Therefore, we reasoned that sFN could act on cancer cells in transit, either in the circulation or about to metastasize, by coating them and preventing their adhesion to distant target organs. In this project, we will expand our studies on sFN for prevention of metastasis in mice, using human breast cancer cells. In preliminary experiments, sFN had a strong anti-metastatic activity. Initial studies also showed that sFN can restrict, in addition to metastasis, the growth of primary breast cancer by mechanisms not yet fully understood. Thus, a second goal of our work will be to follow-up on the mechanism of the tumor growth-inhibiting properties of sFN. In contrast to other common cancer treatments, such as chemotherapy or radiotherapy, no toxic side effects were observed in the treated animals.

 Thus, the treatment effects observed so far and the absence of toxicity makes sFN an outstanding candidate to treat breast cancer, especially since metastasis is not targeted by the available treatments. Our eventual goal is to establish a breast cancer model for future clinical trials using sFN. An unexpected finding of our preliminary work indicates that metastasis may be integrated with tumor growth. Thus, metastasis-targeted approaches could also combat either the primary tumor or the cells already having spread to provide an additional benefit.
Campanulorchis longipes J. Ponert 2017, comb. nov.
Creators: name: Ponert, Jan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Asparagales
Orchidaceae
Campanulorchis
Campanulorchis longipes

description: Campanulorchis longipes (Gagnep.) J.Ponert, comb. nov.
Basionym: Eria longipes Gagnepain (1930: 308).
Type:— VIETNAM. Annam: Nhatrang, 21 May 1922, Poilane 3536 (holotype: P!, P 00403527, lectotype designated by Seidenfaden 1992).
Other specimens examined:— VIETNAM. Annam: Nhatrang, 19 May 1922, Poilane 3435 (P, P00403526); Annam: west of Nhatrang, 25 May 1922, Poilane 3661 (P, P00403528); Annam: Nhatrang, 17 May 1923, Poilane 6504 (P, P00403529); Annam: Darlac, Massif du Chû Yang Sinh, 23 April 1941, Poilane 32531 (P, P00403530); Annam: Darlac, Massif du Chû Yang Sinh, 24 April 1941, Poilane 32540 (P, P00403531).
Notes:— This species is similar to C. globifera (type species of the genus) but differs in several characters: much longer petioles (5–8 cm), slightly wider leaf blades (elliptic to oblong) and larger flowers (sepals 1.8–2.9 cm long) with dark trichomes on the sepals. Campanulorchis longipes has been misinterpreted for a long time, and plants of this taxon are widely cultivated under the names C. globifera or C. thao. The confusion of C. thao with C. globifera and C. longipes is curious as this taxon differs in many characters, especially the yellow and only partially opening flowers (Speckmaier & Sieder 2008). The confusion between C. globifera and C. longipes is much more likely as these taxa have similar flowers but differ especially in the leaf shape and flower size. The clear similarity between these taxa in many characters indicates both should therefore be classified in Campanulorchis.
The two-flowered inflorescence proposed by Seidenfaden (1992) as a diagnostic character of this species does not have any taxonomical value. All specimens in the herbarium of Muséum National d’Histoire Naturelle (P) designated originally as syntypes (Gagnepain 1930) are all single-flowered, and the original description reads “ inflorescentia uniflora ” (Gagnepain 1930). Two-flowered inflorescences could probably occur occasionally depending on conditions as is common in some other orchid species in Podochileae including C. leiophylla and C. pseudoleiophylla. This mistake could probably partially explain frequent incorrect determinations of C. longipes. When using the identification key of Seidenfaden (1992), typical single-flowered specimens would erroneously be excluded from this taxon.
description: Published as part of Ponert, Jan, 2017, New combinations in Campanulorchis (Orchidaceae: Epidendroideae): a reappraisal of the genus, pp. 93-96 in Phytotaxa 323 (1) on pages 93-94, DOI: 10.11646/phytotaxa.323.1.9, http://zenodo.org/record/13696676
Tiarapsylla argentina Jordan 1942
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Stephanocircidae
Tiarapsylla
Tiarapsylla argentina

description: Tiarapsylla argentina Jordan, 1942
NHM. Argentina—Mendoza: San Rafael. Mammalia—Rodentia—Ctenomyidae— Ctenomys mendocinus. Argentina—Chubut: Carhué Niyeu. Jujuy. La Pampa. Mendoza: San Rafael, Malargüe. Santa Fe. Tucumán. Mammalia—Rodentia—Caviidae— Microcavia australis. Cricetidae— Reithrodon auritus. Sanchez & Lareschi (2014).
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 246, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230
Additional file 7: of Metabolic pathways and genes identified by RNA-seq analysis of barley near-isogenic lines differing by allelic state of the Black lemma and pericarp (Blp) gene
Creators: name: Glagoleva, Anastasiya
name: Shmakov, Nikolay
name: Shoeva, Olesya
name: Vasiliev, Gennady
name: Shatskaya, Natalia
name: BĂśrner, Andreas
name: Afonnikov, Dmitry
name: Khlestkina, Elena
Publisher: name: Figshare
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Chromosome 1H scheme of Bowman (BW) and BLP lines. Blp donor segment on chromosome 1H remaining in the BLP NIL, revealed by microsatellite genotyping, is in gray. (PDF 49Â kb)
Priceiella sichuanensis Mey 2017
Creators: name: Gustafsson, Daniel R.
name: Bush, Sarah E.
name: Palma, Ricardo L.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Phthiraptera
Philopteridae
Priceiella
Priceiella sichuanensis

description: Garrulaxeus sichuanensis Mey, 2017
Garrulaxeus sicuanensis Mey, 2017: 163, fig. 85, pl. XV: figs 1–2.
Priceiella (Camurnirmus) sichuanensis (Mey, 2017). New combination.
Type host: Ianthocincla berthemyi (Oustalet, 1876) —buffy laughingthrush.
Type locality: Kuatun, Fukien, China.
Remarks. We tentatively include Garrulaxeus sichuanensis Mey, 2017 in Priceiella (Camurnirmus), due to the similarity between the male genitalia of this species (Mey 2017: fig. 85) and those of Pr. (Camurnirmus) rhinocichlae (Eichler, 1957: figs 88–89), despite the fact that only part of the mesosome of G. sichuanensis is illustrated. The shape of the parameres also suggests that G. sichuanensis should be included in Camurnirmus, and close to Pr. (Camurnirmus) rhinocichlae. However, G. sichuanensis needs to be thoroughly redescribed and illustrated to confirm our subgeneric placement.
description: Published as part of Gustafsson, Daniel R., Bush, Sarah E. & Palma, Ricardo L., 2019, The genera and species of the Brueelia - complex (Phthiraptera: Philopteridae) described by Mey (2017), pp. 252-284 in Zootaxa 4615 (2) on page 274, DOI: 10.11646/zootaxa.4615.2.2, http://zenodo.org/record/3244680
Priceiella sikkimensis Mey 2017
Creators: name: Gustafsson, Daniel R.
name: Bush, Sarah E.
name: Palma, Ricardo L.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Phthiraptera
Philopteridae
Priceiella
Priceiella sikkimensis

description: Garrulaxeus sikkimensis Mey, 2017
Garrulaxeus sikkimensis Mey, 2017: 165, pl. XVI: fig. 2.
Priceiella sikkimensis (Mey, 2017). New combination, incertae sedis.
Type host: Pomatorhinus superciliaris superciliaris (Blyth, 1842) —slender-billed scimitar-babbler.
Type locality: Dib La, Trashiyangsi Valley, East Bhutan.
Remarks. The only illustration of Garrulaxeus sikkimensis Mey, 2017 is a photograph of the female holotype, which does not give enough details to place this species in either Priceiella or Guimaraesiella. The shapes of the subgenital plate and the tergopleurites suggest that G. sikkimensis should be placed in Priceiella, and the head shape would place G. sikkimensis close to the other species of Priceiella on scimitar-babblers, such as Pr. (Thescelovora) austini Gustafsson et al., 2018b, Pr. (Thescelovora) chanthaburiana Gustafsson et al., 2018b and Pr. (Thescelovora) macrocephala Gustafsson et al., 2018b. However, G. sikkimensis, in particular the unknown male, needs a thorough redescription before its relationships can be confirmed. Therefore, we regard it as incertae sedis within Priceiella.
description: Published as part of Gustafsson, Daniel R., Bush, Sarah E. & Palma, Ricardo L., 2019, The genera and species of the Brueelia - complex (Phthiraptera: Philopteridae) described by Mey (2017), pp. 252-284 in Zootaxa 4615 (2) on page 274, DOI: 10.11646/zootaxa.4615.2.2, http://zenodo.org/record/3244680
Campanulorchis pulverulenta J. Ponert 2017, comb. nov.
Creators: name: Ponert, Jan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Asparagales
Orchidaceae
Campanulorchis
Campanulorchis pulverulenta

description: Campanulorchis pulverulenta (Guillaumin) J.Ponert, comb. nov.
Basionym: Eria pulverulenta Guillaumin (1955: 691).
Type:— VIETNAM. Annam: Dalat, 1954, Lambert 30 (P!, P 00403664).
This taxon has been questionable for a long time, as only a badly preserved type specimen exists (Seidenfaden 1982). The discovery of Tixier´s drawing (Seidenfaden 1992) and publication of colour photographs (Speckmaier & Sieder 2008) enabled much more precise characterisation of this species and revealed its similarity to C. thao and other species recently treated in Campanulorchis (Seidenfaden 1992, Speckmaier & Sieder 2008). Because C. thao is likely a close relative of E. pulverulenta, classification in Campanulorchis is proposed here.
description: Published as part of Ponert, Jan, 2017, New combinations in Campanulorchis (Orchidaceae: Epidendroideae): a reappraisal of the genus, pp. 93-96 in Phytotaxa 323 (1) on page 94, DOI: 10.11646/phytotaxa.323.1.9, http://zenodo.org/record/13696676
New Jersey: State of Invention (Flyer)
Creators: name: Rutgers University Libraries
Publisher: name: No Publisher Supplied
Year: 2014

description: A half-day conference was held June 28, 2014, at the Alexander Library of Rutgers, the State University of New Jersey.  The conference focused on New Jersey’s history and present as a state of inventors and inventions with speakers talking about Thomas Edison, Bell Labs and RCA Labs.  The present and future of New Jersey invention was epitomized by a presentation on Solidia, a sustainable concrete that uses CO2 rather than water.  The product is based on a patented process first invented in Rutgers University’s Materials Science Department.  The keynote speaker was Princess Elettra Marconi Giovannelli, the daughter of famed inventor Guglielmo Marconi, who had many ties to the U.S.  and to New Jersey.,  An exhibit and refreshments featuring the many foods invented in New Jersey followed the event.
Novel Breast Cancer Anti-Angiogenic Compounds
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Two decades of experimental evidence has demonstrated that the growth and metastasis of breast cancer are dependent on angiogenesis, the development of new blood vessels. Although over 30 anti-angiogenesis compounds are in clinical trials, we are focusing our search on natural compounds that could readily be given as safe, oral inhibitors. Our search has revealed that an extract from the plant Livistona, a palm tree, can inhibit experimental angiogenesis and suppress breast tumor growth in animal model systems. Preliminary analysis showed that the active compounds are stable to heat, acid, and most likely are small organic molecules. So far, there has been no observed toxicity in mouse experiments.

 In this study, we propose to further isolate and identify the exact chemical structure of the active anti-angiogenesis compound(s). This purification/chemical analysis will be accomplished by ion exchange chromatography, gas chromatography coupled with mass spectrometric analyses, nuclear magnetic resonance, infra-red spectroscopy, and X-ray crystallography. The resulting purified compound(s) will be tested for anti-angiogenesis activity in cellular assays and in mouse tumor models.

 The current list of drugs in development for treating angiogenesis looks promising. However, plant-based compounds have the potential advantage of use in more preventive (chronic) settings and in an orally active form. We think that the discovery of a potent anti-angiogenic drug with low toxicity would potentially be very useful in the treatment and prevention of breast cancer, especially in high-risk women or survivors at risk for recurrence.
Progesterone Action in Human Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Epidemiological studies have clearly established that, excluding the genetic background, reproductive history is an important and consistent "natural" risk factor associated with breast cancer. In particular, both early menarche (beginning of menstruation) and late age onset of menopause have been shown to be associated with an increased breast cancer risk. Thus, it appears that it is the total length of time between menarche and menopause which is associated with the risk factor.

 During each menstrual cycle, the ovaries synthesize and secrete the female sex steroids, estrogen and progesterone. Accordingly, the total length of time between menarche and menopause can be translated as the total years to which the normal breast is exposed to estrogen and progesterone. This, together with the fact that these ovarian steroids have been implicated in breast cancer for more than half a century, argues the need to target estrogen and progesterone as key factors responsible for the observed relationships between the reproductive history and breast cancer risk.

 The normal breast is composed of several cell types and among these, it is the epithelial cells which are the ones most likely to give rise to cancers. In a normal breast, the epithelial cells divide during the progesterone dominant phase of the menstrual cycle, and these cells have a finite life span, such that there is a balance between this cell division and cell death. This balance is uncoupled in tumors accounting for their unrestricted growth. Therefore, by understanding how progesterone controls the division of epithelial cells in the normal breast, we can identify the potential steps which can become deranged and give rise to tumors.

 The action of progesterone is controlled by progesterone receptors which are synthesized in response to estrogen. Therefore, to understand the role of estrogen and progesterone in breast cancer risk, it is particularly critical to understand the role of progesterone receptors on the normal breast. For this, we need to culture human breast epithelial cells containing progesterone receptors. At present, such a culture system does not exist. Although breast tumor cells containing progesterone receptors are available, the use of tumor cells (cells which have already undergone a derangement) is counterproductive for understanding the very basis for such derangement.

 Thus, the goal of our proposal is to create normal human breast epithelial cell lines containing progesterone receptors and examine these for their responses to progesterone so that we may understand the role of progesterone in the breast cancer risk associated with the reproductive history of the female.
Progesterone Receptor and Remodeling of Basement Membrane
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Epidemiological studies have clearly established that, excluding the genetic background, reproductive history is an important and consistent "natural" risk factor associated with breast cancer. In accordance with this, experimental models have clearly established that the female sex hormones, estrogen and progesterone, are essential for the development of both the normal breast and the induction of breast cancer. It is also well established that cancers most often arise from the undifferentiated (immature) structures present most frequently in the breast of females who have never given birth. The breast is composed of many cell types including the epithelial cells, which are the targets of normal growth and are the ones most likely to give rise to cancers. In a normal breast, the epithelial cells grow in response to progesterone, e.g. during the progesterone dominant phase of the menstrual cycle and pregnancy. More importantly, during pregnancy, the undifferentiated structures of the breast are converted to their differentiated (mature) counterparts. Using genetically engineered mice, our laboratory has direct proof that (a) this conversion of undifferentiated structures to differentiated structures requires progesterone and progesterone receptors, the protein through which progesterone action is mediated, and (b) when there is an alteration in the expression of progesterone receptors and progesterone responsiveness, there is abnormal development of mammary glands. Our recent studies also suggest that progesterone and progesterone receptors, in addition to regulating the growth and differentiation of epithelial cells, may also be involved in maintaining the integrity of the basement membrane present at the base of epithelial cells. Loss of basement membrane integrity can lead to migration of epithelial cells into adjacent tissue compartments and, in fact, contributes to the metastatic potential of tumors. Also, tumors with invasive properties are often hormone independent. Therefore, the goal of this project is to identify the potential involvement of progesterone and progesterone receptors in maintaining the integrity of the basement membrane and its link to progesterone and progesterone receptor mediated growth and differentiation of the breast. The results from these studies will provide crucial information with regard to whether a derangement in female sex steroid hormone action can trigger carcinogenesis due to inappropriate regulation and/or interactions with the basement membrane. Also, because of the potential utility of anti-progestins in the treatment of metastatic breast cancer, the results from these studies may also help in the selection of tumors most likely to respond to such treatments.
Malacopsylla grossiventris Weyenbergh 1879
Creators: name: Lareschi, Marcela
name: Sanchez, Juliana
name: Autino, Analía
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Siphonaptera
Malacopsyllidae
Malacopsylla
Malacopsylla grossiventris

description: Malacopsylla grossiventris (Weyenbergh, 1879)
NHM. Argentina—unknown locality. Mammalia—Xenarthra—Dasypodidae— Zaedyus pichiy. Argentina— Buenos Aires: San Adolfo (estancia) near Hilario Ascasubi. Catamarca: El Quimilo Road, Los Nacimientos. Chaco. Chubut: Puerto Lobos. Córdoba. Jujuy: Quinta, San Pedro. La Pampa. Mendoza: La Paz, Puesto La Carpa, Puesto Pugin, Santa Rosa. Salta. San Luis: Don Roberto. Santa Cuz. Santiago del Estero: Icaño. Tucumán: Taco Ralo, Yerba Buena. Mammalia—Carnivora—Canidae: Canis familiaris, Cerdocyon thous, Lycalopex culpaeus, Lycalopex griseus. Mephitidae— Conepatus chinga suffocans. Rodentia—Caviidae— Microcavia australis, «conejo». Xenarthra—Dasypodidae: Dasypus sp., Zaedyus pichiy, Tolypeutes matacus, Chaetophractus vellerosus, Chaetophractus villosus, Euphractus sexcinctus. Lareschi et al. (2010), Ezquiaga & Lareschi (2012).
description: Published as part of Lareschi, Marcela, Sanchez, Juliana & Autino, Analía, 2016, A review of the fleas (Insecta: Siphonaptera) from Argentina, pp. 239-258 in Zootaxa 4103 (3) on page 246, DOI: 10.11646/zootaxa.4103.3.3, http://zenodo.org/record/262230