cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MOESM1 of Shuganyin decoction improves the intestinal barrier function in a rat model of irritable bowel syndrome induced by water-avoidance stress
Creators: name: Lu, Lu
name: Yan, Liang
name: Yuan, Jianye
name: Ye, Qing
name: Lin, Jiang
Publisher: name: figshare
Year: 2018
Subjects: Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Marine Biology

description: Additional file 1. Minimum Standards of Reporting Checklist.
A Lightweight Scheme to Mitigate Deauthentication and Disassociation DoS Attacks in Wireless 802.11 Networks
Creators: name: Noman, Haitham Ameen
name: Shahidan M. Abdullah
name: Nazri Kama
name: Noman, Sinan Ameen
Publisher: name: figshare
Year: 2017
Subjects: subject: 80503 Networking and Communications
subject: FOS: Computer and information sciences
subject: 100503 Computer Communications Networks
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 80303 Computer System Security

description: Wireless 802.11 has many flaws that expose the medium to various types of attacks. The absence of encryption at management and control frames exposes the medium to various types of inevitable Denial of service attacks at Data Link Layer. The attacker may spoof the unencrypted Deauthenticate/Disassociate message with the MAC address of the directed access point and continuously retransmitting it as a broadcast message to all designated clients to disrupt the connection with that particular node. Random bit approach was adapted and implemented in the proposed scheme to provide a layer of authentication in the management frames between the clients and the access point. The proposed scheme showed effectiveness in slowing the attack on both unencrypted and encrypted network by one hour and forty nine seconds without affecting the performance of the medium.
Data and Results
Creators: name: Antillon, Cesar
name: Vega, Anahi
name: Marianita Mora
name: Anderson, Dana
name: Vega, Mellissa
name: Pavon, Ariadna Sosa
name: Saluna, Cecilia Nicole Lim
name: Miranda, Jacob Francisco
Publisher: name: OSF Registries
Year: 2020

description: All data related information for the replication will be stored here.
Review Jurnal Manajemen Pemasaran 2 .pdf
Creators: name: Efni Marta Nadya
Publisher: name: figshare
Year: 2020
Subjects: subject: 159999 Commerce, Management, Tourism and Services not elsewhere classified
subject: FOS: Economics and business

description: Review Jurnal untuk tugas Mata Kuliah Manajemen Pemasaran 2
Additional file 2: Table S2. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology

description: Primer sequences for qRT-PCR. (DOCX 14Â kb)
Additional file 3: Table S3. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Primary antibodies used for the detection of protein expression. (DOCX 14Â kb)
Country-level and Individual-level Predictors of Men's Support for Gender Equality in 42 Countries - methods
Creators: name: Wilkerson, Mariah
Publisher: name: OSF Registries
Year: 2021
Subjects: Country-level & individual level predictors of men's support for gender equality
Scales & items used

description: Country-level and Individual-level Predictors of Men's Support for Gender Equality in 42 Countries.
Trastorno Obsesivo Compulsivo por la Inseguridad y el Desempleo 2010-2015.
Creators: name: Elias, Mario
Publisher: name: figshare
Year: 2017
Subjects: subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine

description: The following investigation is about , how the economic problems in a country are related to unemployement and how this negative situations trigger anxiety dissorders related to stress.
Additional file 1: of Impact of meteorological factors on the incidence of childhood hand, foot, and mouth disease (HFMD) analyzed by DLNMs-based time series approach
Creators: name: Qi, Hongchao
name: Chen, Yue
name: Xu, Dongli
name: Su, Hualin
name: Zhan, Longwen
name: Xu, Zhiyin
name: Huang, Ying
name: He, Qianshan
name: Hu, Yi
name: Lynn, Henry
name: Zhang, Zhijie
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Multilingual abstracts in the six official working languages of the United Nations. (PDF 757Â kb)
Towards Gender Harmony full dataset
Creators: name: Wilkerson, Mariah
Publisher: name: OSF Registries
Year: 2021

description: Towards Gender Harmony project full dataset will be released in 2023. Researchers who wish to use it can contact Towards Gender Harmony Principal Investigator: Natasza Kosakowska-Berezecka, natasza.kosakowska.ug.edu.pl
Additional file 1: Figure S1. of Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex
Creators: name: Jiang, Sirui
name: Nandy, Priya
name: Wang, Wenzhang
name: Ma, Xiaopin
name: Hsia, Jeffrey
name: Wang, Chunyu
name: Wang, Zhenlian
name: Niu, Mengyue
name: Siedlak, Sandra
name: Torres, Sandy
name: Fujioka, Hisashi
name: Xu, Ying
name: Lee, Hyoung-gon
name: Perry, George
name: Liu, Jun
name: Zhu, Xiongwei
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Mental Health

description: Representative western blot and quantification analysis of brain homogenates found the DLP1 and OPA1 protein levels were unchanged in Mfn2 cKOmice (8 weeks of age) compared to control mice in both the hippocampus and the cortex. GAPDH was used as an internal loading control (N = 3/group, data represent mean ± SEM, Student’s t-test, *P < 0.05). Figure S2. Nissl staining of the entire cortex showing neuronal layers I-VI (upper panels) and higher magnification of area encompassing layers III/IV (lower panels). Dashed line represents lower boundary of cortical neurons. Cortical shrinkage is apparent, neuronal layers become less distinct, and nuclei become disfigured and less uniform with age in the cKOmice. Figure S3. Quantification of the immunostaining of (A) GFAP, (B) IBA-1 and (C) MAP2 in the CA1 regions of the Mfn2 cKO mice at different ages (8–28 weeks) compared to control mice at 28 weeks of age (Data represent mean ± SEM, Student’s t-test, *P < 0.05). (PDF 427 kb)
Additional file 4: Table S4. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: S4-i: The expression of HMGA2 protein in normal endometrial tissue (n = 19) and in endometrial carcinoma tissue (n = 80); S4-ii: Association between HMGA2 protein expression and the clinicopathologic characteristics of endometrial cancer patients. (DOCX 16 kb)
"เพิ่ง": การศึกษากระบวนการกลายเป็นคำไวยากรณ์ในสมัยรัตนโกสินทร์
Creators: name: สุนทรี โชติดิลก
Publisher: name: คณะมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา
Year: 2019
Subjects: เพิ่ง, ไวยากรณ์ไทย, กระบวนการกลายเป็นคำไวยากรณ์, Pueng, Thai Grammar, Grammaticalization

description: วารสารมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา, 13, 2, 94-117
การจัดการเรียนรู้การสนทนาทักทาย "สวัสดีคุณครู" ด้วยภาษาไทยในฐานะภาษาที่สอง
Creators: name: ภัคธีมา เพชรพิศาล
Publisher: name: คณะมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา
Year: 2019
Subjects: การจัดการเรียนรู้แบบเน้นประสบการณ์, การสนทนาทักทายภาษาไทยในฐานะภาษาที่สอง, Experiential Learning, Greetings, Thai as a Second Language

description: วารสารมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา, 13, 2, 118-134
การพัฒนาคุณภาพการจัดการศึกษาปฐมวัย: บทบาทผู้บริหาร
Creators: name: ฉัตรวิไล สุรินทร์ชมพู
Publisher: name: คณะมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา
Year: 2019
Subjects: การพัฒนาคุณภาพการศึกษาปฐมวัย, บทบาทผู้บริหารสถานศึกษา, Development of Quality Early Childhood Education, Educational Aministrative Roles

description: วารสารมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา, 13, 2, 135-156
Additional file 2: of Impact of meteorological factors on the incidence of childhood hand, foot, and mouth disease (HFMD) analyzed by DLNMs-based time series approach
Creators: name: Qi, Hongchao
name: Chen, Yue
name: Xu, Dongli
name: Su, Hualin
name: Zhan, Longwen
name: Xu, Zhiyin
name: Huang, Ying
name: He, Qianshan
name: Hu, Yi
name: Lynn, Henry
name: Zhang, Zhijie
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: The comparison of model fit statistics among different lag ranges. (PDF 97Â kb)
Additional file 5: Table S5. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Association between HMGA2 mRNA expression and the clinicopathologic characteristics of endometrial cancer patients (nâ =â 40). (DOCX 16Â kb)
สมาธิ: วิถีแห่งการบำบัดภาวะทางจิตใจ
Creators: name: พิริยานาถ  พีรยาวิจิตร
Publisher: name: คณะมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา
Year: 2019
Subjects: สมาธิ, สมาธิบำบัด, วิถีแห่งการบำบัด, Mental Theraphy, Meditation, Way of Mental

description: วารสารมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา, 13, 2, 157-175
Additional file 3: of Impact of meteorological factors on the incidence of childhood hand, foot, and mouth disease (HFMD) analyzed by DLNMs-based time series approach
Creators: name: Qi, Hongchao
name: Chen, Yue
name: Xu, Dongli
name: Su, Hualin
name: Zhan, Longwen
name: Xu, Zhiyin
name: Huang, Ying
name: He, Qianshan
name: Hu, Yi
name: Lynn, Henry
name: Zhang, Zhijie
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Virology

description: The time series of EMAs for four meteorological variables. (PDF 382Â kb)
เอเชียทีค: ทุนทางวัฒนธรรมกับการสร้างสถานที่ท่องเที่ยวในพื้นที่ย่านทันสมัย
Creators: name: ธวรรณเทพ  มงคลศิริ
Publisher: name: คณะมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา
Year: 2019
Subjects: เอเชียทีค, ทุนวัฒนธรรม, พื้นที่ย่านทันสมัย, Asiatique, Creative folklore, Place

description: วารสารมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา, 13, 2, 176-195
Individual Differences in Collectivism Predict City Identification and City Evaluation in Australian, French, and Turkish Cities
Creators: name: Rubin, Mark
name: Badea, Constantina
name: Condie, Jenna
name: Mahfud, Yara
name: Morrison, Tessa
name: Mujde Peker
Publisher: name: figshare
Year: 2017
Subjects: subject: 170113 Social and Community Psychology
subject: FOS: Psychology

description: Reports the results of a study that shows that people’s general tendency to construe social groups as part of their self predicts their identification with their city, which in turn helps to explain their positive appraisal of their city.
Additional file 6: Figure S1. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: a The baseline expression of HMGA2 in four endometrial cancer cell lines by qRT-PCR. b and c qRT-PCR and western blot analyses were used to determine the transfection efficiency of HMGA2. Data are presented as the mean ± SEM (n = 3 per group). *P < 0.05, ** P < 0.01, *** P < 0.0001. (PDF 507 kb)
Additional file 4: of Impact of meteorological factors on the incidence of childhood hand, foot, and mouth disease (HFMD) analyzed by DLNMs-based time series approach
Creators: name: Qi, Hongchao
name: Chen, Yue
name: Xu, Dongli
name: Su, Hualin
name: Zhan, Longwen
name: Xu, Zhiyin
name: Huang, Ying
name: He, Qianshan
name: Hu, Yi
name: Lynn, Henry
name: Zhang, Zhijie
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The estimation of natural spline for time, indicator variables of weekdays and holiday. (PDF 147Â kb)
Possibly Oriental elements in Slavonic folklore. Kłobuk
Creators: name: Stachowski, Kamil
name: Stachowski, Olaf
Publisher: name: figshare
Year: 2017
Subjects: subject: Linguistics
subject: FOS: Languages and literature

description: The paper discusses a mythical creature known in Polish folklore as kłobuk, how it got its name, the Slavonic background of the word, and its relation to Turkic kalbuk. Usually, the Slavonic word is derived from Turkic; phonetic problems are sometimes mentioned but they do not tend to be viewed as critical. The present paper approaches this established etymology with more reservation and concludes that both Slavistic and Turkological work is necessary in order to connect the two words with an acceptable degree of probability. Bu yazıda Polonya folkloründe kłobuk olarak bilinen mitolojik bir varlık tartşılmakta, bu ismin nasıl alındığı, sözcüğün Slav dillerindeki tabanı ve Türkçe kalbuk ile bağı değerlendirilmektedir. Esasen Slav dillerindeki sözcük Türkçeden kaynaklanmaktadır. Bazen fonetik sorunlardan bahsedilirse de bu eleştirel olarak görülme eğiliminde değildir. Mevcut makale varolan etimolojiye kuşku ile yaklaşır ve hem Slavistiğe hem de Türkolojiye ait çalışmaların kabul edilebilir derecede bir olasılıkla iki kelimenin ilişkilendirilmesi için gerekli olduğu sonucuna varır.
Additional file 7: Figure S2. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: We employed TargetScan and miRanda bioinformatics databases to predict miRNAs that can bind to HMGA2. In total, 25 miRNAs were screened via co-transfection with wild-type dual-luciferase vector-mediated HMGA2 constructs to identify the most suitable miRNAs. Data are presented as the mean ± SEM (n = 3 per group). *P < 0.05, ** P < 0.01, *** P < 0.0001. (PDF 800 kb)
The practice of play
Creators: name: Sherratt, Tim
Publisher: name: figshare
Year: 2017
Subjects: Digital Humanities

description: Keynote presentation at the Deakin University Faculty of Arts and Education HDR Summer School, Geelong, 24 February 2017.
I’m a historian. But in the past decade the nature of my research has changed quite profoundly. Instead of heading off to the archives, taking lots of notes, and writing up a book or an article, I now make things. Generally these things are online, and open to the public. I make things for people to use, to explore, to play, and to ponder.
I started down this track before I realised there was a name for what I do – practice-led research. The things that I make even have their own acronym – they’re NTROs, or Non Traditional Research Outputs.
But practice-led research is not just about making things. New knowledge is generated through cycles of creation and reflection. My aim in making is not to follow a blueprint, or check off a list of requirements, but to end up asking ‘What is this thing?’, ‘What does it do?’, ‘How does it do it?’.
In the past, I’ve tended to talk about my research practice as playing with data. I think there’s an important argument to be made for the role of play in research, particularly when confronted with large cultural datasets. But ‘play’ doesn’t quite capture what I do, nor does it look very convincing in a research proposal. So what do I really do?
Additional file 8: Figure S3. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: qRT-PCR was used to determine the transfection efficiency of the miRNAs. Data are presented as the mean ± SEM (n = 3 per group). *P < 0.05, ** P < 0.01, *** P < 0.0001. (PDF 426 kb)
Additional file 9: Table S6. of miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Creators: name: Ma, Jian
name: Li, Da
name: Kong, Fan-Fei
name: Yang, Di
name: Yang, Hui
name: Ma, Xiao-Xin
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Association between miR-302a-5p expression and the clinicopathologic characteristics of endometrial cancer patients (nâ =â 40). (DOCX 15Â kb)
title: Συρραφές μνήμης _Διαδρομές στο τοπίο της Ελούντας

title: Walking through the memory of Elounda’s landscape
Creators: name: Σισκακη Ευαγγελια
name: Μαυρογιαννη Μαριαννα
Publisher: name: Technical University of Crete
Year: 2022

description: Η διπλωματική εργασία πραγματεύεται τη δημιουργία συρραφών μνήμης μέσω μιας διαδρομής, «πατώντας» στα ίχνη που έχει χαράξει η ιστορία πάνω στο τοπίο της Ελούντας. Πρωτεύων στόχος, η άμεση οικειοποίηση και κατανόηση του χώρου τόσο από τον επισκέπτη όσο και από τον ίδιο τον κάτοικο της περιοχής. Αφετηρία της αποτελεί η πλατεία του οικισμού Σχίσμα και τέρμα της η νήσος της Κολοκύθας. Οι παράκτιες διαμορφώσεις συνδιαλέγονται με τον υπαίθριο αρχαιολογικό χώρο, ο οποίος μετατρέπεται σε υπόσκαφο ιστορικό μουσείο. Στο μουσείο  περιγράφεται ό,τι έχει  «αναγνώσει» ο περιηγητής μέχρι τώρα στο τοπίο. Απόληξη του μουσείου αποτελεί ένας διαμορφωμένος χώρος υπαίθριου αμφιθεάτρου από όπου συνεχίζεται μια περιπατητική διαδρομή που οδηγεί στο παρατηρητήριο. Παράλληλα, η απόληξη του μουσείου λειτουργεί ως είσοδος στο ερευνητικό κέντρο όπου αναλύονται τα ευρήματα της περιοχής. Ως μέρος ενός συνόλου, η νέα διαδρομή συνδέεται με ένα ευρύτερο σύστημα περιπατητικών διαδρομών και σημειακών επεμβάσεων στη νήσο της Κολοκύθας.
นาฏยประดิษฐ์ ชุด โนรีดัดตน
Creators: name: จินตนา อนุวัฒน์
Publisher: name: คณะมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา
Year: 2019
Subjects: นาฏยประดิษฐ์, โนรีดัดตน, ท่ารำซัดท่า, Choreography of Dance, Noree-Dadton, Sattha Dance Pattern

description: วารสารมนุษยศาสตร์และสังคมศาสตร์ มหาวิทยาลัยราชภัฏบ้านสมเด็จเจ้าพระยา, 13, 2, 69-93
Empirical study: Social Media Followers & their impact on risk propensity and tactical decision making in S.M.E.'s
Creators: name: Yang, Brian
Publisher: name: figshare
Year: 2017
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: MBA Thesis for University of Derby, completed April 2016, Marked as Distinction,Nov 2016.
Followed Research Onion (Saunders, et al 2009); integrated ethics through specific consent (written/email) in questionnaires & phone interviews; followed Pragmatist philosphy; researched models & previous studies pertaining to Social Media (specifically Kietzmnann et al, 2011); quantitative results collated via MS Excel & interpreted through IBM program SPSS; qualitative results collated & interpreted through QDA Lite. Conclusions & Summary produced.
Relationship between macroeconomic variables and Malaysia available Shariah Indices
Creators: name: Abdullah, Azrul
name: Norshamshina Mat Isa
name: Zunairah Hassan
Publisher: name: figshare
Year: 2019
Subjects: subject: 150199 Accounting, Auditing and Accountability not elsewhere classified
subject: FOS: Economics and business
subject: 150299 Banking, Finance and Investment not elsewhere classified

description: This paper aims to study the relationship between local and foreign macroeconomic variables and Malaysia available Shariah Indices. In our study, we used the Vector Error Correction (VEC) framework by initially looking at the long run and short run relationship between Malaysia available Shariah indices (i.e. KLSI, FTSE Bursa Malaysia EMAS Shariah Index and FTSE Bursa Malaysia Hijrah Shariah Index) and the macroeconomic variables via the Johansen cointegration technique. Monthly data during the twenty two-year period (from January 1990 to December 2011) has been collected from DataStream and tested. The findings show positive relationship between the variables from 1990 to 2006. However, mix results were found after the period till 2011. This study then conclude that the standardized set of macroeconomic variables that specified by earlier researchers still can be relied but in careful policy formulation.
Additional file 1: Table S1. of LncRNA HOTAIR promotes cell migration and invasion by regulating MKL1 via inhibition miR206 expression in HeLa cells
Creators: name: Zheng, Peng
name: Yin, Ze
name: Wu, Ying
name: Xu, Yao
name: Luo, Ying
name: Zhang, Tong-Cun
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology

description: The list of primers sequences. (DOCX 29 kb)
Female Education Changes and Continuation of Gender Roles in Urban India by Ambika Kohli
Creators: name: Kohli, Ambika
Publisher: name: figshare
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology

description: Article 26 of the UniversalDeclaration of Human Rights isperceived as an important tool forwomen’s empowerment throughwhich women can break differentsociocultural barriers. But aqualitative study conductedamong 45 married urban womenin Delhi and Yamuna Nagardistrict of Haryana explains howeducation is used to maintain theexisting gender hierarchies andgender division of labour. Ithighlights that reproduction andtransformation of socialstructures are evident in anovel manner where ideas ofwomen’s emancipation andsubordination coexist.
Additional file 1: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine

description: Comparison of Aβ42 levels and amyloid burden in male and female 5XFAD mice at 4 months of age. The graphs represent levels of human Aβ42 (A) and percentage of area occupied by Thioflavin-S positive plaques (B) in hippocampus and cortex from male and female GGA3WT;5XFAD, GGA3Het;5XFAD and GGA3KO;5XFAD mice at 4 months of age. Levels of Aβ42 (A) and amyloid burden (B) were significantly higher in females than in males with the same genotype. Total number of mice in each group is indicated within bars. All graphs represent mean ± SEM. Two-way ANOVA with Fisher’s LSD post hoc tests was applied to each sex group. #### < 0.0001. (PDF 666 kb)
Additional file 2: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Mental Health
subject: Plant Biology

description: GGA3 deletion does not increase levels of BACE1-generated APP-CTFs at 4 months of age in 5XFAD mice.(A) Representative immunoblots of hippocampus (left) and cortex (right) homogenates from 4 months old GGA3WT;5XFAD, GGA3Het;5XFAD, and GGA3KO;5XFAD mice probed with anti-APP C-terminal (C1/6.1) and anti-GAPDH (MAB374) antibodies. C99 and C89 fragments are BACE1-mediated APP C-terminal fragments (APP-CTFs), while C83 fragment is alpha-secretase-mediated APP-CTF. APP-CTFs are present as phosphorylated (pC99, pC89, and pC83) and nonphosphorylated (C99, C89, and C83) forms. (B) Densitometry levels of full-length APP (fAPP), pC99, C99, and pC89 were quantified, and normalized to GAPDH or fAPP. Table shows the summary of total APP levels (fAPP/GAPDH) and BACE1-mediated processing of APP (pC99/fAPP, C99/fAPP, pC89/fAPP) in hippocampus and cortex homogenates from 4 months old GGA3WT;5XFAD, GGA3Het;5XFAD, and GGA3KO;5XFAD mice. One-way ANOVA with Fisher’s LSD post hoc tests was applied to each genotype group. (PDF 543 kb)
Manual for iCGPA_author version.pdf
Creators: name: Muhammad, Ahmad Mazli
Publisher: name: figshare
Year: 2017
Subjects: subject: 130103 Higher Education
subject: FOS: Educational sciences
subject: 130199 Education systems not elsewhere classified

description: This manual facilitates academics in understanding and implementing learning outcome, constructive alignment, assessment and curriculum design.
Empirical study: Socail Media Followers & their impact on risk propensity and tactical decision making in S.M.E.'s
Creators: name: Yang, Brian
Publisher: name: figshare
Year: 2017
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: MBA Thesis for University of Derby, completed April 2016, Marked as Distinction,Nov 2016.
Followed Research Onion (Saunders, et al 2009); integrated ethics through specific consent (written/email) in questionnaires & phone interviews; followed Pragmatist philosphy; researched models & previous studies pertaining to Social Media (specifically Kietzmnann et al, 2011); quantitative results collated via MS Excel & interpreted through IBM program SPSS; qualitative results collated & interpreted through QDA Lite. Conclusions & Summary produced.
Additional file 3: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health

description: Comparison of Aβ42 levels and amyloid burden in male and female 5XFAD mice at 12 months of age. The graphs represent human Aβ42 levels (A) and quantification of Thioflavin-S positive plaques (B-D) in hippocampus and cortex from 12 months old GGA3WT;5XFAD, GGA3Het;5XFAD and GGA3KO;5XFAD male and female mice. Levels of Aβ42 are significantly higher in hippocampus and cortex from females than from males with the same genotype (A). Amyloid burden was not significantly different between males and females, except in the cortex from GGA3KO;5XFAD mice (B). (C-D) The graphs represent the average size of amyloid plaques (μm2) and the number of amyloid plaques in hippocampus (C) and cortex (D) of GGA3WT;5XFAD and GGA3KO;5XFAD mice. The number of amyloid plaques, but not their size, was significantly higher in the cortex of females compared to males. Total number of mice in each group is indicated within bars. All graphs represent mean ± SEM. Two-way ANOVA with Fisher’s LSD post hoc tests was applied to each sex group. # p < 0.05, ## p < 0.01, #### < 0.0001. (PDF 1118 kb)
Additional file 4: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health
subject: Computational Biology

description: Levels of transgenic human APP increase with age in APPswe/PS1ΔE9 mice. Representative immunoblot of hippocampus and cortex homogenates from 4 and 10 months old APPswe/PS1ΔE9 female mice probed with anti-APP C-terminal (C1/6.1) and anti-GAPDH (MAB374) antibodies. Increased BACE1 levels are observed in cortex, but not in hippocampus homogenates from 10 months of APPswe/PS1ΔE9 mice compared to 4 months old mice. Old APPswe/PS1ΔE9 mice have significantly increased transgenic APP levels in both hippocampus and cortex compared to 4 months old mice. (PDF 525 kb)
Examining middle-class women’s reproductive agency in collective and patriarchal settings of urban northern India by Ambika Kohli
Creators: name: Kohli, Ambika
Publisher: name: figshare
Year: 2017
Subjects: subject: Sociology
subject: FOS: Sociology

description: This qualitative study explores how urban middle-class north Indian women from the states of Haryana and Delhipractise their reproductive agency within collective and patriarchal settings. Snowballing was used to recruitparticipants; 45 married urban middle-class women who have children were interviewed. Analysis was conductedusing Pierre Bourdieu’s concept of capital. Many studies take the view that Indian women’s reproductive choicesare controlled by their husbands and in-laws, suggesting that women are oppressed and without agency. However,this study indicates that women do receive support within their affinal families that influences their choices butdoes not necessarily indicate they are oppressed. These women, while practicing their agency, aim to achieve theirinterests through strategies of resistance and/or negotiation within the patriarchal settings of their affinal families.Their ability to both negotiate and resist suggests that agency is at once transformative and reproductive.
Additional file 5: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: GGA3 deletion does not increase levels of BACE1-generated APP-CTFs age in 12 months old 5XFAD mice. (A) Representative immunoblots of hippocampus homogenates from 12 months old GGA3WT;5XFAD, GGA3Het;5XFAD, and GGA3KO;5XFAD males (left) and females (right) probed with anti-APP C-terminal (C1/6.1) and anti-GAPDH (MAB374) antibodies. (B) Densitometry levels of full-length APP (fAPP), pC99, C99, and pC89 were quantified, and normalized to GAPDH or fAPP. Table shows the summary of total APP levels (fAPP/GAPDH) and BACE1-mediated processing of APP (pC99/fAPP, C99/fAPP, pC89/fAPP) in hippocampus homogenates from 12 months old GGA3WT;5XFAD, GGA3Het;5XFAD, and GGA3KO;5XFAD mice. One-way ANOVA with Fisher’s LSD post hoc tests was applied to each genotype group. (PDF 531 kb)
Additional file 6: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Plant Biology

description: Detection of soluble and membrane-bound CHL1 fragments in mouse hippocampus. Representative immunoblot of soluble and membrane fractions compared to total protein extracts from BACE1WY, BACE1Het and BACE1KO mice. Snap frozen hippocampi from 12 months old BACE1WT, BACE1Het, and BACE1KO mice were separated in PBS soluble fraction (Soluble), membrane fraction (Membrane), and total protein extract (Total) as described in method. Samples were separated in 3–8% Tris-acetate gels to detect CHL1_FL and CHL1_NTF using anti-CHL1 (AF2147) antibody. Western blot analysis of CHL1 clearly detected two membrane bound CHL1 fragments in the membrane fraction, corresponding to CHL1_FL (~ 185 kDa) and the ~ 175 kDa band (arrowhead) also detected in the total extract (Figs. 4b and 9a). CHL1_FL levels were increased in BACE1KO in the membrane fraction and total extract. CHL1_βNTF was detected in the soluble fraction and corresponds to the ~ 165 kDa band detected in the total extract. A fragment of lower molecular weight (indicated by an asterisk) was detected in the soluble fraction from BACE1KO mice. Such soluble fragment is most likely derived by a compensatory increased cleavage of CHL1 by ADAM8 or ADAM10. As expected membrane proteins including calnexin and BACE1 were absent in the soluble fraction. (PDF 1089 kb)
Additional file 7: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health

description: BACE1-mediated cleavage of CHL1 is reduced in old 5XFAD mice. (A) Representative immunoblot of PBS soluble fraction (Soluble) and membrane fraction (Membrane) from the hippocampus of BACE1KO, BACEHet, wild type (indicated as GGA3WT), GGA3KO, 5XFAD, and BACE1Het;5XFAD mice using anti-CHL1 (AF2147), anti-calnexin (610523), anti-BACE1 (D10E5), and anti-GAPDH (MAB374) antibodies. Increased levels of CHL1_FL were observed in mice with reduced BACE1 (BACE1Het, BACE1Het;5XFAD, and BACE1KO) compared to GGA3WT mice while a decrease in CHL1_FL levels was only observed in mice with elevated BACE1 (GGA3KO). Levels of CHL1_FL were increased in old 5XFAD mice compared with wild type mice. Soluble CHL1_βNTF was also increased in 5XFAD mice compared to wild type mice. A soluble CHL1 fragment was detected in BACEKO mice (asterisk), which may be derived by compensatory increased ADAM8 or ADAM 10 cleavage. (B) Graphs represent the ratio CHL1_FL/Calnexin, CHL1_βNTF/GAPDH, and CHL1_βNTF/CHL1_FL in five different genotypes. GGA3KO mice showed significantly increased ratio of CHL1_βNTF/CHL1_FL compared with GGA3WT mice. BACE1Het, 5XFAD, and BACE1Het;5XFAD mice exhibited reduced ratio of CHL1_βNTF/CHL1_FL, suggesting these mice has reduced BACE1-mediated CHL1 processing. Total number of mice in each group is indicated within bars. All graphs represent mean ± SEM. One-way ANOVA with Fisher’s LSD post hoc tests were applied to each genotype group. * p < 0.05, *** p < 0.001, **** < 0.0001. (PDF 1248 kb)
Additional file 8: of BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
Creators: name: Kim, WonHee
name: Ma, Liang
name: Lomoio, Selene
name: Willen, Rachel
name: Lombardo, Sylvia
name: Dong, Jinghui
name: Haydon, Philip
name: Tesco, Giuseppina
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health

description: CHL1 expression is similar in 5XFAD and 5XFAD mice. (A) mRNA expression levels for CHL1 were analyzed in the hippocampus of non-5XFAD (non-5XFAD) and 5XFAD (5XFAD) mice by RT-qPCR. 5XFAD mice had similar level of mRNA Chl1. (B) mRNA Chl1 levels were analyzed in the hippocampus of 5XFAD males and females, indicating no sex difference in 5XFAD mice. Total number of mice in each group is indicated within bars. All graphs represent mean ± SEM. Unpaired t-test with Welch’s correction was performed. (PDF 337 kb)
QSAR analysis for 6-arylpyrazine-2-carboxamides as Trypanosoma brucei inhibitors
Creators: name: V. H. Masand
name: N. N. E. El-Sayed
name: D. T. Mahajan
name: V. Rastija
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Human African trypanosomiasis (HAT) is prevalent in African countries, covering 37 countries, mostly sub-Saharan. A limited number of drugs are available to cure this neglected disease. In the present work, quantitative structure–activity (toxicity) relationships (QSA(T)R) analysis has been performed for a dataset of 54 6-arylpyrazine-2-carboxamides as Trypanosoma brucei inhibitors to identify the important structural features required for future optimization of lead candidates. The QSA(T)R models satisfy OECD guidelines and have high statistical robustness. The QSA(T)R models are based on easily interpretable molecular descriptors. The QSA(T)R models indicate that Trypanosoma brucei inhibitory activity of 6-arylpyrazine-2-carboxamides has correlation with the presence of N-sec-butylformamide and substituted benzene. The results could be beneficial for further optimization of 6-arylpyrazine-2-carboxamides as Trypanosoma brucei inhibitors. Some potential candidate molecules have been proposed.
Structure-based modelling, scoring, screening, and in vitro kinase assay of anesthetic pkc inhibitors against a natural medicine library
Creators: name: B. X. Shi
name: F. R. Chen
name: X. Sun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Protein kinase C (PKC) is an intracellular effector of the inositol phosphate-mediated signal transduction pathway. Evidence is emerging that certain general anaesthetics can influence the activity of PKC by interacting with the regulatory domain of the enzyme, and targeting PKC kinase domain is considered as a strategy to modulate the anaesthetic effects. Here, an integrated method was used to perform virtual screening against a large library of natural compounds for the discovery of new and potent PKC modulators. A number of hits were identified and their inhibitory activity against PKC kinase domain was measured by using a standard kinase assay protocol. Three and five compounds were determined to have high and moderate activities with IC50 values at nanomolar and micromolar levels, respectively. These compounds can be considered as promising lead molecular entities to develop efficacious anaesthetic modulators. Structural examination revealed a variety of nonbonded interactions such as hydrogen bonds, cation-π contacts, and hydrophobic forces across the complex interface of PKC with the identified compounds. This study helps to establish an integrative approach to rational kinase inhibitor discovery by efficiently exploiting various existing natural products.
Comparison of small intestinal submucosa and polypropylene mesh for abdominal wall defect repair
Creators: name: Wang, Zhu-Le
name: Wu, Shi-Zhou
name: Li, Zhi-Feng
name: Guo, Jin-Hai
name: Zhang, Yi
name: Pi, Jin-Kui
name: Hu, Jun-Gen
name: Yang, Xi-Jing
name: Huang, Fu-Guo
name: Xie, Hui-Qi
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Abdominal wall defects are a common medical problem, and inadequate repair methods can lead to serious complications. Abdominal wall reconstruction using autologous tissue, or non-biological, biological, or composite patches is often performed to repair defective areas. In particular, composite patches containing both polymeric and biological materials have gained increasing attention due to their good mechanical properties and biocompatibility. However, it is still unclear whether the quality of repairs using composite patches is superior to that of a biological patch. Based on the limitations of previous studies, we compared small intestinal submucosa (SIS) patches with SIS + polypropylene mesh (PPM) patches for repairing abdominal wall defects in adult beagle dogs. Forty-five female dogs were subjected to surgical resection to produce abdominal wall defects. SIS or SIS + PPM was used as patch for the defects. Morphology, biomechanics, and histological evaluations were performed to evaluate the efficacy and safety of such therapies. Our findings demonstrated that SIS had advantages over SIS + PPM considering biological activity and histocompatibility without increasing the risk of repair failure.
ECAS score: a web-based risk model to predict moderate and severe extracranial carotid artery stenosis
Creators: name: Yan, Yinglin
name: Gao, Suying
name: Yang, Hongna
name: Qin, Shangmin
name: Li, Fang
name: Zhang, Guangbo
name: Yang, Bo
name: He, Yan
name: Zhao, Yongna
name: Li, Enjing
name: Xu, Lihua
name: Zhang, Na
name: Fan, Dongna
name: Liu, Dongliang
name: Yu, Kai
name: Ji, Ruijun
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: To develop and validate a risk model (Extracranial Carotid Artery Stenosis score, ECAS score) to predict moderate and severe ECAS. Furthermore, we compared discrimination of the ECAS score and three existing models with regard to both moderate and severe ECAS. The ECAS score was developed based on the Renqiu Stroke Screening Study (RSSS), in which eligible patients were randomly divided into derivation (60%) and validation (40%) cohorts. ECAS was diagnosed by carotid duplex ultrasound according to the published criteria. Independent predictors of moderate (≥50%) and severe (≥70%) ECAS were obtained using multivariable logistic regression. The area under the receiver operating characteristic curve (AUROC) and the Hosmer–Lemeshow test were used to assess model discrimination and calibration. A total of 5010 participants were included and the mean age was 64.3. The proportion of ECAS of < 50%, 50–69%, 70–99% and occlusion was 4.4, 0.5, 0.4, and 0.4%, respectively. The ECAS score was developed from sets of predictors of moderate and severe ECAS. The ECAS score demonstrated good discrimination in the derivation and validation cohorts (AUROC range: 0.785–0.846). The Hosmer–Lemeshow tests of ECAS score for moderate and severe ECAS were not significant in the derivation and validation cohorts (all P > 0.05). When compared to the three existing models, the ECAS score showed significantly better discrimination for both moderate and severe ECAS (all P < 0.001). The ECAS score is a valid model for predicting moderate and severe ECAS. Further validation of the ECAS score in different populations and larger samples is warranted.