cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity
Creators: name: Steiner, Sophie
name: Schwarz, Tatjana
name: Corman, Victor M.
name: Gebert, Laura
name: Kleinschmidt, Malte C.
name: Wald, Alexandra
name: Gläser, Sven
name: Kruse, Jan M.
name: Zickler, Daniel
name: Peric, Alexander
name: Meisel, Christian
name: Meyer, Tim
name: Staudacher, Olga L.
name: Wittke, Kirsten
name: Kedor, Claudia
name: Bauer, Sandra
name: Besher, Nabeel Al
name: Kalus, Ulrich
name: Pruß, Axel
name: Drosten, Christian
name: Volk, Hans-Dieter
name: Scheibenbogen, Carmen
name: Hanitsch, Leif G.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: primary immunodeficiencies (PID)
subject: primary antibody deficiency (PAD)
subject: coronavirus disease 2019 (COVID-19)
subject: severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
subject: convalescent plasma (CP)
subject: type I interferons
subject: innate immunity
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Morbidity and mortality of COVID-19 is increased in patients with inborn errors of immunity (IEI). Age and comorbidities and also impaired type I interferon immunity were identified as relevant risk factors. In patients with primary antibody deficiency (PAD) and lack of specific humoral immune response to SARS-CoV-2, clinical disease outcome is very heterogeneous. Despite extensive clinical reports, underlying immunological mechanisms are poorly characterized and levels of T cellular and innate immunity in severe cases remain to be determined. In the present study, we report clinical and immunological findings of 5 PAD patients with severe and fatal COVID-19 and undetectable specific humoral immune response to SARS-CoV-2. Reactive T cells to SARS-CoV-2 spike (S) and nucleocapsid (NCAP) peptide pools were analyzed comparatively by flow cytometry in PAD patients, convalescents and naive healthy individuals. All examined PAD patients developed a robust T cell response. The presence of polyfunctional cytokine producing activated CD4(+) T cells indicates a memory-like phenotype. An analysis of innate immune response revealed elevated CD169 (SIGLEC1) expression on monocytes, a surrogate marker for type I interferon response, and presence of type I interferon autoantibodies was excluded. SARS-CoV-2 RNA was detectable in peripheral blood in three severe COVID-19 patients with PAD. Viral clearance in blood was observed after treatment with COVID-19 convalescent plasma/monoclonal antibody administration. However, prolonged mucosal viral shedding was observed in all patients (median 67 days) with maximum duration of 127 days. PAD patients without specific humoral SARS-CoV-2 immunity may suffer from severe or fatal COVID-19 despite robust T cell and normal innate immune response. Intensified monitoring for long persistence of SARS-CoV-2 viral shedding and (prophylactic) convalescent plasma/specific IgG as beneficial treatment option in severe cases with RNAemia should be considered in seronegative PAD patients.
Additional file 1 of Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
Creators: name: Yamamoto, Takaya
name: Niibe, Yuzuru
name: Aoki, Masahiko
name: Shintani, Takashi
name: Yamada, Kazunari
name: Kobayashi, Mitsuru
name: Hideomi Yamashita
name: Masatoki Ozaki
name: Manabe, Yoshihiko
name: Onishi, Hiroshi
name: Yahara, Katsuya
name: Nishikawa, Atsushi
name: Katsui, Kuniaki
name: Ryoong-Jin Oh
name: Atsuro Terahara
name: Jingu, Keiichi
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer

description: Additional file 1.
Mapping Yearly Fine Resolution Global Surface Ozone through the BME Data Fusion of Observations and Model Output for 1990–2017
Creators: name: DeLang, Marissa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Estimates of ground-level ozone concentrations are necessary to determine the human health burden of ozone. To support the 2019 Global Burden of Disease Study, we produce fine resolution global surface ozone estimates for each year from 1990 to 2017 through the statistical fusion of observations and atmospheric chemistry models. We use the Bayesian Maximum Entropy (BME) framework to integrate surface observations with a multi-model composite, which is the linear combination of atmospheric models that best reproduces observations. The BME estimates match observations at each monitoring site with the influence of an observation decreasing across space and time. After estimating at 0.5° resolution using BME, we add fine spatial detail based on a fine resolution model. Our final product estimates annual global surface ozone for 1990-2017 at 0.1° resolution, and shows a positive trend in population weighted ozone globally, driven by highly populated and polluted regions of Asia and Africa.
Management of Obstructive Sleep Apnea in Patients With Heart Failure
Creators: name: Wang, Youmeng
name: Schöbel, Christoph
name: Penzel, Thomas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: heart failure
subject: treatment
subject: obstructive sleep apnea
subject: central sleep apnea
subject: PAP
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Sleep apnea is traditionally classified as obstructive sleep apnea (OSA), which occurs when the upper airway collapses due to the relaxation of oropharyngeal musculature, and central sleep apnea occurs when the brainstem cannot stimulate breathing. Most sleep apnea in patients with heart failure (HF) results from coexisting OSA and central sleep apnea (CSA), or complex sleep apnea syndrome. OSA and CSA are common in HF and can be involved in its progression by exposure to the heart to intermittent hypoxia, increased preload and afterload, activating sympathetic, and decreased vascular endothelial function. A majority of treatments have been investigated in patients with CSA and HF; however, less or short-term randomized trials demonstrated whether treating OSA in patients with HF could improve morbidity and mortality. OSA could directly influence the patient's recovery. This review will focus on past and present studies on the various therapies for OSA in patients with HF and summarize CSA treatment options for reasons of reference and completeness. More specifically, the treatment covered include surgical and non-surgical treatments and reported the positive and negative consequences for these treatment options, highlighting possible implications for clinical practice and future research directions.
(3713) Charles Edward Baines
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Relativistic scalar particle subject to a confining potential and Lorentz symmetry breaking effects in the cosmic string spacetime
Creators: name: Belich, H.
name: Bakke, K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The behaviour of a relativistic scalar particle subject to a scalar potential under the effects of the violation of the Lorentz symmetry in the cosmic string spacetime is discussed. It is considered two possible scenarios of the Lorentz symmetry breaking in the CPT-even gauge sector of the Standard Model Extension defined by a tensor $\left(K_{F}\right)_{μναβ}$. Then, by introducing a scalar potential as a modification of the mass term of the Klein-Gordon equation, it is shown that the Klein-Gordon equation in the cosmic string spacetime is modified by the effects of the Lorentz symmetry violation backgrounds and bound state solution to the Klein-Gordon equation can be obtained.
description: 16 pages, no figure. arXiv admin note: text overlap with arXiv:1407.6279, arXiv:1412.5080
(3716) Lilley Ann Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
A four-year observational study to examine the dietary impact of the North Carolina Healthy Food Small Retailer Program, 2017–2020
Creators: name: Ammerman, A.S.
name: Jilcott Pitts, S.B.
name: Haynes-Maslow, L.
name: Fleischhacker, S.
name: Laska, M.N.
name: Rafferty, A.P.
name: Johnson, N.
name: McGuirt, J.T.
name: Bell, R.A.
name: Wu, Q.
name: Truesdale, K.P.
name: Boys, K.A.
name: Kaur, A.P.
Publisher: name: BioMed Central Ltd
Year: 2021

description: Background: The North Carolina (NC) Healthy Food Small Retailer Program (HFSRP) was passed into law with a $250,000 appropriation (2016–2018) providing up to $25,000 in funding to small food stores for equipment to stock healthier foods and beverages. This paper describes an observational natural experiment documenting the impact of the HFSRP on store food environments, customers’ purchases and diets. Methods: Using store observations and intercept surveys from cross-sectional, convenience customer samples (1261 customers in 22 stores, 2017–2020; 499 customers in 7 HFSRP stores, and 762 customers in 15 Comparison stores), we examined differences between HFSRP and comparison stores regarding: (1) change in store-level availability, quality, and price of healthy foods/beverages; (2) change in healthfulness of observed food and beverage purchases (“bag checks”); and, (3) change in self-reported and objectively-measured (Veggie Meter®-assessed skin carotenoids) customer dietary behaviors. Differences (HFSRP vs. comparison stores) in store-level Healthy Food Supply (HFS) and Healthy Eating Index-2010 scores were assessed using repeated measure ANOVA. Intervention effects on diet were assessed using difference-in-difference models including propensity scores. Results: There were improvements in store-level supply of healthier foods/beverages within 1 year of program implementation (0 vs. 1–12 month HFS scores; p = 0.055) among HFSRP stores only. Comparing 2019 to 2017 (baseline), HFSRP stores’ HFS increased, but decreased in comparison stores (p = 0.031). Findings indicated a borderline significant effect of the intervention on self-reported fruit and vegetable intake (servings/day), though in the opposite direction expected, such that fruit and vegetable intake increased more among comparison store than HFSRP store customers (p = 0.05). There was no significant change in Veggie Meter®-assessed fruit and vegetable intake by customers shopping at the intervention versus comparison stores. Conclusions: Despite improvement in healthy food availability, there was a lack of apparent impact on dietary behaviors related to the HFSRP, which could be due to intervention dose or inadequate statistical power due to the serial cross-sectional study design. It may also be that individuals buy most of their food at larger stores; thus, small store interventions may have limited impact on overall eating patterns. Future healthy retail policies should consider how to increase intervention dose to include more product marketing, consumer messaging, and technical assistance for store owners.
Additional file 2 of Neck pain patterns and subgrouping based on weekly SMS-derived trajectories
Creators: name: Irgens, P.
name: A. Kongsted
name: B. L. Myhrvold
name: K. Waagan
name: K. B. Engebretsen
name: B. Natvig
name: N. K. Vøllestad
name: H. S. Robinson
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. English translation baseline questionnaire.
Associations between shopping patterns, dietary behaviors, and Geographic Information System-assessed store accessibility among small food store customers
Creators: name: Truesdale, K.P.
name: Wu, Q.
name: Ammerman, A.S.
name: Laska, M.N.
name: Jilcott Pitts, S.B.
name: McGuirt, J.T.
name: Rafferty, A.P.
name: Bell, R.A.
Publisher: name: Cambridge University Press
Year: 2020

description: Objective: To examine associations between Geographic Information Systems (GIS)-assessed accessibility to small food stores, shopping patterns, and dietary behaviors among small food store customers. Design: Residential addresses and customer shopping patterns (frequency of shopping, previous purchase of fruits and vegetables) were gathered through customer intercept surveys. Addresses were geocoded and GIS-assessed distance and driving time from the participants' residence to the store were calculated. Dietary status and behaviors were assessed using an objective non-invasive measure of skin carotenoids, the National Cancer Institute Fruit and Vegetable Screener, and items to assess sugary beverage intake. Associations between distance and driving time, demographics, shopping frequency, prior reported purchase of fruits and vegetables at the store, and dietary behaviors were examined. Setting: Small food stores (n=22) across North Carolina. Participants: Cross-sectional convenience samples of English-speaking customers aged 18 or older (n=692). Results: Participants living closer to the small store had lower income and formal education were more likely to be Black, more likely to have previously bought fruits and vegetables at the store, and more frequently shopped at the store. In adjusted models, skin carotenoids (n=644) were positively associated with distance to the store from home in miles (p = 0.01). Conclusions: Customers who lived closer to the stores were more frequent shoppers and more likely to have previously purchased fruits and vegetables at the store yet had lower skin carotenoids. These results support continued efforts to examine how to increase the availability and promotion of healthful foods at small food retail stores.
Emergence of energy dependence in the fragmentation of heterogeneous materials
Creators: name: Pal, Gergo
name: Varga, Imre
name: Kun, Ferenc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: The most important characteristics of the fragmentation of heterogeneous solids is that the mass (size) distribution of pieces is described by a power law functional form. The exponent of the distribution displays a high degree of universality depending mainly on the dimensionality and on the brittle-ductile mechanical response of the system. Recently, experiments and computer simulations have reported an energy dependence of the exponent increasing with the imparted energy. These novel findings question the phase transition picture of fragmentation phenomena, and have also practical importance for industrial applications. Based on large scale computer simulations here we uncover a robust mechanism which leads to the emergence of energy dependence in fragmentation processes resolving controversial issues on the problem: studying the impact induced breakup of plate-like objects with varying thickness in three dimensions we show that energy dependence occurs when a lower dimensional fragmenting object is embedded into a higher dimensional space. The reason is an underlying transition between two distinct fragmentation mechanisms controlled by the impact velocity at low plate thicknesses, while it is hindered for three-dimensional bulk systems. The mass distributions of the subsets of fragments dominated by the two cracking mechanisms proved to have an astonishing robustness at all plate thicknesses, which implies that the non-universality of the complete mass distribution is the consequence of blending the contributions of universal partial processes.
description: 9 pages, 8 figures
Snacking characteristics and patterns and their associations with diet quality and BMI in the Childhood Obesity Prevention and Treatment Research Consortium
Creators: name: Nicastro, H.L.
name: Robinson, T.N.
name: Berge, J.M.
name: Matheson, D.M.
name: Thomas, A.J.
name: Truesdale, K.P.
name: Karp, S.M.
name: Moore, S.M.
name: Lecroy, M.N.
Publisher: name: Cambridge University Press
Year: 2019

description: Objective: To describe snacking characteristics and patterns in children and examine associations with diet quality and BMI. Design: Children's weight and height were measured. Participants/adult proxies completed multiple 24 h dietary recalls. Snack occasions were self-identified. Snack patterns were derived for each sample using exploratory factor analysis. Associations of snacking characteristics and patterns with Healthy Eating Index-2010 (HEI-2010) score and BMI were examined using multivariable linear regression models. Setting: Childhood Obesity Prevention and Treatment Research (COPTR) Consortium, USA: NET-Works, GROW, GOALS and IMPACT studies. Participants: Predominantly low-income, racial/ethnic minorities: NET-Works (n 534, 2-4-year-olds); GROW (n 610, 3-5-year-olds); GOALS (n 241, 7-11-year-olds); IMPACT (n 360, 10-13-year-olds).Results: Two snack patterns were derived for three studies: a meal-like pattern and a beverage pattern. The IMPACT study had a similar meal-like pattern and a dairy/grains pattern. A positive association was observed between meal-like pattern adherence and HEI-2010 score (P for trend < 0-01) and snack occasion frequency and HEI-2010 score (β coefficient (95 % CI): NET-Works, 0-14 (0-04, 0-23); GROW, 0-12 (0-02, 0-21)) among younger children. A preference for snacking while using a screen was inversely associated with HEI-2010 score in all studies except IMPACT (β coefficient (95 % CI): NET-Works, -3-15 (-5-37, -0-92); GROW, -2-44 (-4-27, -0-61); GOALS, -5-80 (-8-74, -2-86)). Associations with BMI were almost all null. Conclusions: Meal-like and beverage patterns described most children's snack intake, although patterns for non-Hispanic Blacks or adolescents may differ. Diets of 2-5-year-olds may benefit from frequent meal-like pattern snack consumption and diets of all children may benefit from decreasing screen use during eating occasions.
A THESIS SUBMITTED TO THE SCHOOL OF GRADUATE STUDIES OF ADDIS ABABA UNIVERSITY, IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTERS IN PUBLIC HEALTH
Creators: name: ALEMAYEHU TARIKU JIMALO
Publisher: name: Zenodo
Year: 2018

description: Background: The purpose of antenatal care is to improve pregnancy outcome

for both the mother and the fetus. Antenatal care is more beneficial in

preventing adverse pregnancy outcomes when it is sought early in the

pregnancy and continued through to delivery. However, existing evidence

from developing countries including Ethiopia indicate that few women seek

ANC at early stage of their pregnancy.

Objective: The objective of this study is to assess timing of fist

antenatal care booking and factors that influence the timing.

Method: A cross sectional study design was used to collect data from

630 pregnant women who were attending antenatal care service at 10

government health centers in Addis Ababa from March 1 to 30, 2008.
Data Management Plan under the H2020 Open Research Data Pilot
Creators: name: Sørdahl, Patrick Berg
Publisher: name: Zenodo
Year: 2020
Subjects: Case Study
Common Fishery Policy
Decision Support Network
Fisheries Partnership Agreement
Joint Scientific Committee
Framework Programme for Research and Development
Horizon 2020
Maximum Sustainable Yield
International Fishing Waters
High Seas

description: The overall goal of WP2 in FarFish is to "advance knowledge and collate data related to biological characteristics of the main fish stocks in the selected fisheries, and to evaluate the appropriateness, relevance and applicability of stock assessment models currently in use for these fisheries", as per the DoA. Task 2.2 and deliverable 2.2 contributes towards these goals by creating a "Data Management Plan", as per the Horizon 2020 Open Research Data Pilot. The deliverable contains 14 forms detailing the content of all datasets used within FarFish, how it will be preserved, and steps taken to make data publically available after the project end.
description: This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no. 727891.
Additional file 1 of Neck pain patterns and subgrouping based on weekly SMS-derived trajectories
Creators: name: Irgens, P.
name: A. Kongsted
name: B. L. Myhrvold
name: K. Waagan
name: K. B. Engebretsen
name: B. Natvig
name: N. K. Vøllestad
name: H. S. Robinson
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. English translation weekly SMS questions.
Baseline diet quality of predominantly minority children and adolescents from households characterized by low socioeconomic status in the Childhood Obesity Prevention and Treatment Research (COPTR) Consortium
Creators: name: Jaka, M.M.
name: Truesdale, K.P.
name: McAleer, S.
name: Sommer, E.C.
name: Pratt, C.A.
name: Matheson, D.M.
Publisher: name: BioMed Central
Year: 2019

description: Background: The Healthy Eating Index (HEI-2010) is a measure of diet quality that examines conformance with the Dietary Guidelines for Americans. The objectives of this study were to estimate baseline diet quality of predominantly low-income minority children using the HEI-2010 and to identify the most important HEI components to target for dietary intervention. Methods: Two or three baseline 24 h dietary recalls were collected in-person or over telephone between May 2012 and June 2014 from 1,745 children and adolescents from four randomized clinical trials in the Childhood Obesity Prevention and Treatment Research (COPTR) Consortium. Nine adequacy and three moderation food components were calculated and averaged to determine overall HEI scores. The overall HEI-2010 scores were categorized as ≥81, 51-80, or ≤ 50 based on the HEI-2005 classification. For each study, mean overall and component HEI scores were estimated using linear regression models. Results: Mean (95% CI) overall HEI scores ranged from 47.9 (46.8, 49.0) to 64.5 (63.6, 65.4). Only 0.3 to 8.1% of children and adolescents had HEI-2010 score ≥ 81. The average component score for green and beans was less than 30% of maximum score for all trials. In contrast, the average component score for protein, dairy (except for IMPACT), and empty calories (except forIMPACT) was more than 80% of maximum score. Conclusions: Based on HEI-2010 scores, few children and adolescents consumed high quality diets. Dietary interventions for children and adolescents should focus on improving intakes of green vegetables and beans. Clinical trial registry numbers: GROW study (clinical trial # NCT01316653); NET-Works study (clinical trial #NCT01606891); Stanford Goals (clinical trial #NCT01642836); IMPACT (clinical trial # NCT01514279).
Semi-autonomous, context-aware, agent using behaviour modelling and reputation systems to authorize data operation in the Internet of Things
Creators: name: Copigneaux, Bertrand
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computers and Society (cs.CY)
subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: In this paper we address the issue of gathering the "informed consent" of an end user in the Internet of Things. We start by evaluating the legal importance and some of the problems linked with this notion of informed consent in the specific context of the Internet of Things. From this assessment we propose an approach based on a semi-autonomous, rule based agent that centralize all authorization decisions on the personal data of a user and that is able to take decision on his behalf. We complete this initial agent by integrating context-awareness, behavior modeling and community based reputation system in the algorithm of the agent. The resulting system is a "smart" application, the "privacy butler" that can handle data operations on behalf of the end-user while keeping the user in control. We finally discuss some of the potential problems and improvements of the system.
description: This work is currently supported by the BUTLER Project co-financed under the 7th framework program of the European Commission. published in Internet of Things (WF-IoT), 2014 IEEE World Forum, 6-8 March 2014, Seoul, P411-416, DOI: 10.1109/WF-IoT.2014.6803201, INSPEC: 14255656
Additional file 4 of Neck pain patterns and subgrouping based on weekly SMS-derived trajectories
Creators: name: Irgens, P.
name: A. Kongsted
name: B. L. Myhrvold
name: K. Waagan
name: K. B. Engebretsen
name: B. Natvig
name: N. K. Vøllestad
name: H. S. Robinson
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 4: Supplementary Table 2. Intensity of symptoms after pain-free period. NP intensity and weekly days with pain in the first week following a pain-free period of 1 to > 20 weeks for analysis of robustness of pattern and subgroup definitions.
(3714) Arthur Baines
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Recruitment strategies for predominantly low-income, multi-racial/ethnic children and parents to 3-year community-based intervention trials: Childhood Obesity Prevention and Treatment Research (COPTR) Consortium
Creators: name: Escarfuller, J.
name: Lotas, L.J.
name: Pemberton, V.
name: Hotop, A.M.
name: Ward, D.S.
name: Casey, T.L.
name: French, S.A.
name: Robinson, T.N.
name: Pratt, C.A.
name: Cui, Z.
name: Po'E, E.
name: Andrisin, S.
name: Matheson, D.
name: Truesdale, K.P.
Publisher: name: BioMed Central Ltd.
Year: 2019

description: Background: The recruitment of participants into community-based randomized controlled trials studying childhood obesity is often challenging, especially from low-income racial/ethnical minorities and when long-term participant commitments are required. This paper describes strategies used to recruit and enroll predominately low-income racial/ethnic minority parents and children into the Childhood Obesity Prevention and Treatment Research (COPTR) consortium. Methods: The COPTR consortium has run four independent 3-year, multi-level (individual, family, school, clinic, and community) community-based randomized controlled trials. Two were prevention trials in preschool children and the other two were treatment trials in pre-adolescents and adolescent youth. All trials reported monthly participant recruitment numbers using a standardized method over the projected 18-24 months of recruitment. After randomization of participants was completed, recruitment staff and investigators from each trial retrospectively completed a survey of recruitment strategies and their perceived top three recruitment strategies and barriers. Results: Recruitment was completed in 15-21 months across trials, enrolling a total of 1745 parent-child dyads- out of 6314 screened. The number of children screened per randomized child was 4.6 and 3.5 in the two prevention trials, and 3.1 and 2.5 in the two treatment trials. Recruitment strategies reported included: (1) careful planning, (2) working with trusting community partners, (3) hiring recruitment staff who were culturally sensitive, personality appropriate, and willing to work flexible hours, (4) contacting potential participants actively and repeatedly, (5) recruiting at times and locations convenient for participants, (6) providing incentives to participants to complete baseline measures, (7) using a tracking database, (8) evaluating whether participants understand the activities and expectations of the study, and (9) assessing participants' motivation for participating. Working with community partners, hiring culturally sensitive staff, and contacting potential participants repeatedly were cited by two trials among their top three strategies. The requirement of a 3-year commitment to the trial was cited by two trials to be among the top three recruitment barriers. Conclusions: Comprehensive strategies that include community partnership support, culturally sensitive recruitment staff, and repeated contacts with potential participants can result in successful recruitment of low-income racial/ethnic minority families into obesity prevention and treatment trials.
Additional file 1 of Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP
Creators: name: Hien, Annie
name: Molinaro, Gemma
name: Botao Liu
name: Huber, Kimberly M.
name: Richter, Joel D.
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Validation of differential expression results from Tsc2+/− versus wild type from Fig. 1. Histogram of the number of differentially expressed genes called from 4990 random permutations of sample labels for the genotype comparison from a RNA-seq and b ribosome profiling. Fig. S2. a Density plot of the length (left) and minimal free energy (MFE) (right) of the 5′UTR of Down and Up RPFs in Tsc2+/− compared to all mRNAs. ns nonsignificant, Wilcoxon rank-sum test with correction by Bonferroni method. b The ratios of phosphorylated/total mTOR, rpS6, and 4EBP1 as determined by western blots of whole hippocampal lysates are unchanged in Tsc2+/− mice as compared to wild-type littermates (n = 13–15 mice/genotype, ns non-significant, unpaired t test). c Total levels of RPL4, RPS25, and LARP1 from hippocampus of wild-type and Tsc2+/− littermates (n = 13–15 mice/genotype, ns = nonsignificant, unpaired t test). d Pearson correlation coefficient was computed for pairs of transcript features including translation efficiency (TE), coding length, and GC content (CDS), 5′ untranslated region length and GC content (5′UTR), 3′ untranslated region length and GC content (3′UTR), and RNA abundance (TPM, transcripts per million). Red indicates a positive correlation, and blue a negative correlation. Gray indicates a correlation of identical parameters. p
The evolution, complexity and diversity of models of long-term forest dynamics
Creators: name: Bugmann, Harald
name: Seidl, Rupert
Publisher: name: Zenodo
Year: 2022
Subjects: Forest gap model
Dynamic global vegetation model
forest landscape model
Model evolution
model design
JABOWA
ecological modelling
global change ecology

description: 1. To assess the impacts of climate change on vegetation from stand to global scales, models of forest dynamics that include tree demography are needed. Such models are now available for 50 years, but the currently existing diversity of model formulations and its evolution over time are poorly documented. This hampers systematic assessments of structural uncertainties in model-based studies. 2. We conducted a meta-analysis of 28 models, focusing on models that were used in the past five years for climate change studies. We defined 52 model attributes in five groups (basic assumptions, growth, regeneration, mortality and soil moisture) and characterized each model according to these attributes. Analyses of model complexity and diversity included hierarchical cluster analysis and redundancy analysis. 3. Model complexity evolved considerably over the past 50 years. Increases in complexity were largest for growth processes, while complexity of modelled establishment processes increased only moderately. Model diversity was lowest at the global scale, and highest at the landscape scale. We identified five distinct clusters of models, ranging from very simple models to models where specific attribute groups are rendered in a complex manner and models that feature high complexity across all attributes. 4. Most models in use today are not balanced in the level of complexity with which they represent different processes. This is the result of different model purposes, but also reflects legacies in model code, modelers' preferences, and the 'prevailing spirit of the epoch'. The lack of firm theories, laws and 'first principles' in ecology provides high degrees of freedom in model development, but also results in high responsibilities for model developers and the need for rigorous model evaluation. 5. Synthesis. The currently available model diversity is beneficial: convergence in simulations of structurally different models indicates robust projections, while convergence of similar models may convey a false sense of certainty. The existing model diversity – with the exception of global models – can be exploited for improved projections based on multiple models. We strongly recommend balanced further developments of forest models that should particularly focus on establishment and mortality processes, in order to provide robust information for decisions in ecosystem management and policymaking.
description: Microsoft Excel to open the data compilation R or R Studio to load and execute the scriptFunding provided by: European Union
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100000780
Award Number: 101001905
description: The collection and processing of the dataset are fully described in the paper.
Two family interventions to reduce BMI in low-income urban youth: A randomized trial
Creators: name: Truesdale, K.P.
name: Borawski, E.A.
name: Hardin, H.K.
name: Casey, T.
name: Nevar, A.
name: Moore, S.M.
name: Jones, S.
name: Adegbite-Adeniyi, C.
name: Trapl, E.S.
name: Thomas, C.
name: Long, M.
name: Plow, M.
name: Pratt, C.A.
name: McAleer, S.
name: Love, T.E.
name: Uli, N.K.
name: Stevens, J.
Publisher: name: American Academy of Pediatrics
Year: 2019

description: BACKGROUND: Our primary aim was to evaluate the effects of 2 family-based obesity management interventions compared with a control group on BMI in low-income adolescents with overweight or obesity. METHODS: In this randomized clinical trial, 360 urban-residing youth and a parent were randomly assigned to 1 of 2 behaviorally distinct family interventions or an education-only control group. Eligible children were entering the sixth grade with a BMI $85th percentile. Interventions were 3 years in length; data were collected annually for 3 years. Effects of the interventions on BMI slope (primary outcome) over 3 years and a set of secondary outcomes were assessed. RESULTS: Participants were primarily African American (77%), had a family income of,25 000 per year, and obese at enrollment (68%). BMI increased over time in all study groups, with group increases ranging from 0.95 to 1.08. In an intent-to-treat analysis, no significant differences were found in adjusted BMI slopes between either of the family-based interventions and the control group (P = .35). No differences were found between the experimental and control groups on secondary outcomes of diet, physical activity, sleep, perceived stress, or cardiometabolic factors. No evidence of effect modification of the study arms by sex, race and/or ethnicity, household income, baseline levels of child and parent obesity, or exposure to a school fitness program were found. CONCLUSIONS: In this low-income, adolescent population, neither of the family-based interventions improved BMI or health-related secondary outcomes. Future interventions should more fully address poverty and other social issues contributing to childhood obesity.
Metallicity Distribution Functions of Four Local Group dwarf galaxies
Creators: name: Ross, Teresa L.
name: Holtzman, Jon A.
name: Saha, Abhijit
name: Anthony-Twarog, Barbara J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present stellar metallicities in Leo I, Leo II, IC 1613, and Phoenix dwarf galaxies derived from medium (F390M) and broad (F555W, F814W) band photometry using the Wide Field Camera 3 (WFC3) instrument aboard the Hubble Space Telescope. We measured metallicity distribution functions (MDFs) in two ways, 1) matching stars to isochrones in color-color diagrams, and 2) solving for the best linear combination of synthetic populations to match the observed color-color diagram. The synthetic technique reduces the effect of photometric scatter, and produces MDFs 30-50 % narrower than the MDFs produced from individually matched stars. We fit the synthetic and individual MDFs to analytical chemical evolution models (CEM) to quantify the enrichment and the effect of gas flows within the galaxies. Additionally, we measure stellar metallicity gradients in Leo I and II. For IC 1613 and Phoenix our data do not have the radial extent to confirm a metallicity gradient for either galaxy. We find the MDF of Leo I (dwarf spheroidal) to be very peaked with a steep metal rich cutoff and an extended metal poor tail, while Leo II (dwarf spheroidal), Phoenix (dwarf transition) and IC 1613 (dwarf irregular) have wider, less peaked MDFs than Leo I. A simple CEM is not the best fit for any of our galaxies, therefore we also fit the `Best Accretion Model' of Lynden-Bell 1975. For Leo II, IC 1613 and Phoenix we find similar accretion parameters for the CEM, even though they all have different effective yields, masses, star formation histories and morphologies. We suggest that the dynamical history of a galaxy is reflected in the MDF, where broad MDFs are seen in galaxies that have chemically evolved in relative isolation and narrowly peaked MDFs are seen in galaxies that have experienced more complicated dynamical interactions concurrent with their chemical evolution.
description: 15 pages, 8 figures, accepted in AJ
(3710) Arthur Guy Gisburn
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Quasi-Lie families, schemes, invariants and their applications to Abel equations
Creators: name: Cariñena, J. F.
name: de Lucas, J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 34A26 (primary), 34A34, 53Z05 (secondary)

description: This work analyses types of group actions on families of $t$-dependent vector fields of a particular class, the hereby called quasi-Lie families. We devise methods to obtain the defined here quasi-Lie invariants, namely a kind of functions constant along the orbits of the above-mentioned actions. Our techniques lead to a deep geometrical understanding of quasi-Lie schemes and quasi-Lie systems giving rise to several new results. Our achievements are illustrated by studying Abel and Riccati equations. We retrieve the Liouville invariant and study other new quasi-Lie invariants of Abel equations. Several Abel equations with a superposition rule are described and we characterise Abel equations via quasi-Lie schemes.
description: 23 pages
Statistical features of magnetic noise in mixed-type impact fracture
Creators: name: Danku, Zsuzsa
name: Lenkey, Gyongyver B.
name: Kun, Ferenc
Publisher: name: arXiv
Year: 2015
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We study the statistical features of magnetic noise accompanying the dynamic fracture of steel samples during mixed type fracture, where the overall ductile character of crack propagation is interrupted by a sudden brittle jump. The structure of the voltage time series is investigated by identifying discrete peaks which correspond to elementary steps of the jerky cracking process. We show that the height, duration, area, and energy of peaks have power law distributions with exponents falling close to the corresponding values of pure ductile fracture. For single peaks a power law correlation of the height and area with the width is evidenced, however, the mixed nature of fracture gives rise to a crossover between two regimes of different exponents. The average pulse shape of micro-cracking events has a parabolic form with a right handed asymmetry similarly to quasi-static fracture propagation. The asymmetry emerges due to stress localization at the advancing crack front.
description: 4 pages, 5 figures
Supplementary document for Detection and Mapping of Specular Surfaces Using Multibounce Lidar Returns - 6202449.pdf
Creators: name: Henley, Connor
name: Somasundaram, Siddharth
name: Hollmann, Joseph
name: Raskar, Ramesh
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Supplement 1
One-year follow-up examination of the impact of the North Carolina healthy food small retailer program on healthy food availability, purchases, and consumption
Creators: name: Pitts, S.B.J.
name: Haynes-Maslow, L.
name: Laska, M.N.
name: McGuirt, J.T.
name: Truesdale, K.P.
name: Ammerman, A.
name: Wu, Q.
name: Bell, R.
Publisher: name: MDPI AG
Year: 2018

description: We examined the short-term impact of the North Carolina Healthy Food Small Retailer Program (HFSRP), a legislatively appropriated bill providing funding up to $25,000 to small food retailers for equipment to stock and promote healthier foods, on store-level availability and purchase of healthy foods and beverages, as well as customer dietary patterns, one year post-policy implementation. We evaluated healthy food availability using a validated audit tool, purchases using customer bag-checks, and diet using self-reported questionnaires and skin carotenoid levels, assessed via Veggie Meter™, a non-invasive tool to objectively measure fruit and vegetable consumption. Difference-in-difference analyses were used to examine changes in HFSRP stores versus control stores after 1 year. There were statistically significant improvements in healthy food supply scores (availability), with the Healthy Food Supply HFS score being −0.44 points lower in control stores and 3.13 points higher in HFSRP stores pre/post HFSRP (p = 0.04). However, there were no statistically significant changes in purchases or self-reported consumption or skin carotenoids among customers in HFSRP versus control stores. Additional time or other supports for retailers (e.g., marketing and promotional materials) may be needed for HFSRP implementation to influence purchase and consumption.
Phylogenomics shows unique traits in Noctilucales are derived rather than ancestral
Creators: name: Cooney, Elizabeth
name: Leander, Brian
name: Keeling, Patrick
Publisher: name: Zenodo
Year: 2022
Subjects: Noctilucales
dinoflagellate evolution
Amphidinium
Abediniales
single cell transcriptomics

description: Dinoflagellates are a diverse group of protists that possess many unique traits. These include (but are not limited to) expansive genomes packaged into permanently condensed chromosomes, photosynthetic or cryptic plastids acquired vertically or horizontally in serial endosymbioses, and a ruffle-like transverse flagellum attached along its length to the cell. When reconstructing character evolution, early branching lineages with unusual features that distinguish them from the rest of the group have proven useful for inferring ancestral states. The Noctilucales are one such lineage, possessing relaxed chromosomes in some life stages and a trailing, thread-like transverse flagellum. However, most of the cellular and molecular data for the entire group come from a single cultured species, Noctiluca scintillans, and because its phylogenetic position is unresolved, it remains unclear if these traits are ancestral or derived. Here, we use single cell transcriptomics to characterize three diverse Noctilucales genera: Spatulodinium, Kofoidinium, and a new lineage, Fabadinium gen. nov. We also provide transcriptomes for undescribed species in Amphidinium and Abediniales, critical taxa for clarifying the phylogenetic position of Noctilucales. Phylogenomic analyses suggest that the Noctilucales are sister to Amphidinium rather than an independent branch outside the core dinoflagellates. This topology is consistent with observations of shared characteristics between some members of Noctilucales and Amphidinium and provides the most compelling evidence to date that the unusual traits within this group are derived rather than ancestral. We also confirm that Spatulodinium plastids are photosynthetic and of ancestral origin, and show that all non-photosynthetic Noctilucales retain plastid genes indicating a cryptic organelle.
description: Funding provided by: Gordon and Betty Moore Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000936
Award Number: 9201Funding provided by: Natural Sciences and Engineering Research Council of Canada
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100000038
Award Number: 2019-03986Funding provided by: Natural Sciences and Engineering Research Council of Canada
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100000038
Award Number: 2019-03994