cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Structural and functional implications of ABCC1 variants on clinical statin response
Creators: name: Tropéia, Naomí Crispim
name: Freire, Paula Paccielli
name: de Alencar Pereira, Eduardo Willian
name: Sampaio, Marcelo Ferraz
name: Borges, Jéssica Bassani
name: Bastos, Gisele Medeiros
name: Thurow, Helena Strelow
name: Castro, Lara Reinel
name: Nakazone, Marcelo Arruda
name: Carmo, Tayanne Silva
name: Hirata, Mario Hiroyuki
name: Ferreira, Glaucio Monteiro
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: ATP-binding cassette (ABC) proteins are membrane transporters responsible for metabolites and active substances removal from cells. Their genes’ variations have been associated with protein function and expression defects. Familial Hypercholesterolemia (FH) patients hosting those alterations might compromise the efficacy of high-dose statin treatment, a primary therapeutic strategy. ABCC1 is a member of the ABC-transporter superfamily, potentially relevant to pharmacological therapy responses and toxicity risks in hypercholesterolemic patients. Here, we evaluated specific non-synonymous (SNV) missense variants in the ABCC1 gene from a FH patient cohort, assessing potential impacts on protein structure, molecular dynamics and interactions with rosuvastatin, atorvastatin, pravastatin, pitavastatin, and lovastatin. Molecular docking, complemented by motion, visual and binding affinity analysis using the PLANNET model, suggested that these mutations had minimal impact on drug interactions. These findings prompted further analysis of two other efflux pumps, ABCG2 and P-gp, and their statin interactions. Interestingly, diminished binding affinities hinted at a compensatory mechanism wherein other transporters might mitigate potential ABCC1 mutation effects, ensuring effective drug efflux. Clinical profiles from the patient cohort did not show a correlation between these variants and clinical outcomes, potentially pointing to the role of alternate drug transporters in statin interaction. Diagram depicting the compensatory turnover of alternate transporters in response to statins’ preferential binding to ABCC1, and its impact on the clinical outcomes for patients with familial hypercholesterolemia. It represents how ABCG2 (pink) and P-gp (orange) are more capable of depleting statins from the intracellular ambient than ABCC1 (purple), thus impacting statin treatment.
Foster Kids from Poor Families—Exploring the Adoption and Safe Families Act of 1997
Creators: name: McFeely, Brendan
Publisher: name: University of Notre Dame
Year: 2023

description: Award Category: Sophomores, Juniors, Seniors \u000a\u000a Project Completed for: The Politics of Poverty in the United States (POLS30113) \u000a\u000a For more information, please visit https://library.nd.edu/library-research-award.
A New Bridge for Luang Prabang: Balancing Heritage and Commerce (Luang Prabang, Laos)
Creators: name: Johnson, Christian
Publisher: name: University of Notre Dame
Year: 2023

description: Beyond ordinary utility, infrastructure should be an elegant component of the city that supports the local architecture, social infrastructure, and the local urban economy. The contingent architecture, in return, should support the practicality and beauty of the infrastructure. When infrastructure, buildings, and neighborhoods are beautiful and interconnected, they transcend the mundane and signal a place that is loved and worth preserving.
High-pressure phase transitions in BiFeO3: hydrostatic vs. non-hydrostatic conditions
Creators: name: Guennou, Mael
name: Bouvier, Pierre
name: Haumont, Raphaël
name: Garbarino, Gaston
name: Kreisel, Jens
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We report high-pressure x-ray diffraction experiments on BiFeO3 (BFO) single crystals in diamond-anvil cells up to 14 GPa. Two data sets are compared, one in hydrostatic conditions, with helium used as pressure-transmitting medium, and the other in non-hydrostatic conditions, with silicon oil as pressure-transmitting medium. It is shown that the crystal undergoes different phase transitions in the two cases, highlighting the high sensitivity of BFO to non-hydrostatic stress. Consequences for the interpretation of high-pressure structural studies are discussed.
description: 6 pages, 4 figures
Inflation and late time acceleration in braneworld cosmological models with varying brane tension
Creators: name: Wong, K. C.
name: Cheng, K. S.
name: Harko, T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Braneworld models with variable brane tension $λ$ introduce a new degree of freedom that allows for evolving gravitational and cosmological constants, the latter being a natural candidate for dark energy. We consider a thermodynamic interpretation of the varying brane tension models, by showing that the field equations with variable $λ$ can be interpreted as describing matter creation in a cosmological framework. The particle creation rate is determined by the variation rate of the brane tension, as well as by the brane-bulk energy-matter transfer rate. We investigate the effect of a variable brane tension on the cosmological evolution of the Universe, in the framework of a particular model in which the brane tension is an exponentially dependent function of the scale factor. The resulting cosmology shows the presence of an initial inflationary expansion, followed by a decelerating phase, and by a smooth transition towards a late accelerated de Sitter type expansion. The varying brane tension is also responsible for the generation of the matter in the Universe (reheating period). The physical constraints on the model parameters, resulted from the observational cosmological data, are also investigated.
description: 25 pages, 8 figures, accepted for publication in European Physical Journal C
Sites of art and networks of data: Archiving artists' websites as linked open data
Creators: name: Rossenova, Lozana
Publisher: name: Zenodo
Year: 2023
Subjects: web archiving
digital archives
digital preservation

description: Artist websites are sites of art where ‘digital social memory’ gets accrued over time. As such, they require preservation care similar to other forms of cultural heritage. This essay describes several sets of medium-specific, socio-technical challenges to archiving artist websites connected to the processes of both archiving published materials on the web, as well as subsequently providing access to these materials via an indexed database. These challenges can be grouped under the rubrics of ethics, technology, curation, as well as cataloguing and sustainability. The primary focus of the essay is to discuss the challenges – and opportunities – associated with cataloguing and structuring digital archive (meta)data, by drawing upon findings from the practice-led research project to redesign the ArtBase archive of net art, alongside two further case studies. All case studies present critical engagements with Linked Open Data (LOD) software environments as means to collaboratively organize, store and provide access to heterogeneous archive data on the web. The possibility to capture and represent complex networks of relations and dependencies through the flexible structure of LOD is key to the concluding policy recommendations.
description: Art Doc Archive developed a prototype for the centralized archiving of the materials self-documented by Berlin-based artists on websites and in social media. The "Reclaim your Archive!" series of articles accompanied the project and was edited by Bianca Ludewig. All texts can be found on the project's blog: reclaim.hypotheses.org
Absence and artlessness in Early Modern Church of England martyr portraits
Creators: name: Muckart, Heather
Publisher: name: University of British Columbia
Year: 2023

description: This dissertation examines sixteenth- and seventeenth-century portraits of early modern Church of England martyrs, and how they emerged from and engaged with the violent religious conflicts that occurred during the long Reformation of England (1534-1688). The official religion of England changed rapidly during this period. This meant that members of various confessions were executed at different moments for the crime of heresy. Religiously motivated executions were quite dangerous for the state, because they held the potential to transform the body of the criminal into that of the martyr. Most of the Church of England martyrs were executed during the reign of Mary I (r. 1553-58), when nearly 300 men, women, and children were burned at the stake. Commemorative portraits of these martyrs were produced, importantly, in a variety of mediums and throughout the early modern period. Also studied are the posthumous portraits of Charles I who upon his beheading was popularly reframed as the martyr king. The basis for identifying a Church of England martyr relied heavily upon the faculty of sight, and much of the discourse on martyrdom in this period was couched in the terms of vision. Pictorial depictions of the martyrs register some of the anxieties generated by this reliance upon outward appearances. These portraits also dangerously evoked the contested portrayals of Catholic saints. Various tactics were therefore undertaken to minimize associations with depictions of Catholic saints, including the insertion of text, the removal of explicit references to transcendence, and an increasing preference for the medium of print. The thesis reviews how various representational strategies used to depict the Church of England martyrs—successes as well as failures—partially converted these real-life people into forms of national religious archetypes. In representations of martyrs, their personal and professional identities were overwritten by the terms of martyrdom. Portraits of them, the dissertation argues, bring to light nascent understandings of English nationhood in the form of religious ideals that were manifested in the absent body of the dead martyr. Over time, the polysemous bodies of these early modern martyrs became part of the mythos of the English nation.
Effects of f(R) Dark Energy on Dissipative Anisotropic Collapsing Fluid
Creators: name: Sharif, M.
name: Kausar, H. Rizwana
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The purpose of this paper is to study the effects of dark energy on dynamics of the collapsing fluid within the framework of metric f(R) gravity. The fluid distribution is assumed to be locally anisotropic and undergoing dissipation in the form of heat flow, null radiations and shear viscosity. For this purpose, we take general spherical symmetric spacetime. Dynamical equations are obtained and also some special solutions are found by considering shearing expansionfree evolution of the fluid. It is found that dark energy affects the mass of the collapsing matter and rate of collapse but does not affect the hydrostatic equilibrium.
description: 16 pages, accepted for publication in Mod. Phys. Lett. A
Nonparametric Dark Energy Reconstruction from Supernova Data
Creators: name: Holsclaw, Tracy
name: Alam, Ujjaini
name: Sanso, Bruno
name: Lee, Herbert
name: Heitmann, Katrin
name: Habib, Salman
name: Higdon, David
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Understanding the origin of the accelerated expansion of the Universe poses one of the greatest challenges in physics today. Lacking a compelling fundamental theory to test, observational efforts are targeted at a better characterization of the underlying cause. If a new form of mass-energy, dark energy, is driving the acceleration, the redshift evolution of the equation of state parameter w(z) will hold essential clues as to its origin. To best exploit data from observations it is necessary to develop a robust and accurate reconstruction approach, with controlled errors, for w(z). We introduce a new, nonparametric method for solving the associated statistical inverse problem based on Gaussian Process modeling and Markov chain Monte Carlo sampling. Applying this method to recent supernova measurements, we reconstruct the continuous history of w out to redshift z=1.5.
description: 4 pages, 2 figures, accepted for publication in Physical Review Letters
The Mass Distribution of SDSS J1004+4112 Revisited
Creators: name: Oguri, Masamune
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a strong lens analysis of SDSS J1004+4112, a unique quasar lens produced by a massive cluster of galaxies at z=0.68, using a newly developed software for gravitational lensing. We find that our parametric mass model well reproduces all observations including the positions of quasar images as well as those of multiply imaged galaxies with measured spectroscopic redshifts, time delays between quasar images, and the positions of faint central images. The predicted large total magnification of μ~ 70 suggests that the lens system is indeed a useful site for studying the fine structure of a distant quasar and its host galaxy. The dark halo component is found to be unimodal centered on the brightest cluster galaxy and the Chandra X-ray surface brightness profile. In addition, the orientation of the halo component is quite consistent with those of the brightest cluster galaxy and member galaxy distribution, implying that the lensing cluster is a relaxed system. The radial profile of the best-fit mass model is in good agreement with a mass profile inferred from the X-ray observation. While the inner radial slope of the dark halo component is consistent with being -1, a clear dependence of the predicted A-D time delay on the slope indicates that an additional time delay measurement will improve constraints on the mass model.
description: 9 pages, 5 figures, accepted for publication in PASJ. The lens software presented in the paper available at http://www.slac.stanford.edu/~oguri/glafic/
Turkish Public Opinion and the EU Membership: between Support and Mistrust
Creators: name: Şenyuva, Özgehan
Publisher: name: Zenodo
Year: 2018
Subjects: European Union; EU-Turkey Relations; EU Membership; Public Opinion; Turkish Public Support; Level of Trust

description: FEUTURE Online Paper No. 26

The support for EU memberhip is very volatile among Turkish public opinion. Over the years it has been going through different ups and downs, although it has been consistently low for the last five years. This papers analyzes the changes in the Turkish public’s support level to the EU membership and links them to the developments in Turkey-EU relations. The paper also demonstrates that two other major indicators are more stable indicators of Turkish public opinion and the EU: the level of trust to the EU and the eventuality of Turkish membership. The paper finishes with a discussion on the interplay between political discourses and the public opinion in Turkey and how the lack of trust is being utilized for political gains.
description: This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 692976. This publication reflects the views only of the authors, and the Commission cannot be held responsible for any use which may be made of the information contained therein.
Charged Cylindrical Collapse of Anisotropic Fluid
Creators: name: Sharif, M.
name: Fatima, Sundas
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Following the scheme developed by Misner and Sharp, we discuss the dynamics of gravitational collapse. For this purpose, an interior cylindrically symmetric spacetime is matched to an exterior charged static cylindrically symmetric spacetime using the Darmois matching conditions. Dynamical equations are obtained with matter dissipating in the form of shear viscosity. The effect of charge and dissipative quantities over the cylindrical collapse are studied. Finally, we show that homogeneity in energy density and conformal flatness of spacetime are necessary and sufficient for each other.
description: 19 pages, accepted for publication in Gen. Relativ. Grav
The Church looks at some social questions
Creators: name: Schieder, Joseph E.
Publisher: name: University of Notre Dame
Year: 2023

description:
 Catholic pamphlet.
 Modern youth -- our most precious heritage / by Joseph E Schieder ; Leadership in the modern world / by John F. Cronin ; The Church and health care / by D.A. McGowan ; Are you satisfied with your schools? / by F. Hochwalt.
 Catholic hour (Radio program)
Optical Dielectric Functions of III-V Semiconductors in Wurtzite Phase
Creators: name: De, Amrit
name: Pryor, Craig E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Optical properties of semiconductors can exhibit strong polarization dependence due to crystalline anisotropy. A number of recent experiments have shown that the photoluminescence intensity in free standing nanowires is polarization dependent. One contribution to this effect is the anisotropy of the dielectric function due to the fact that most nanowires crystalize in the wurtzite form. While little is known experimentally about the band structures wurtzite phase III-V semiconductors, we have previously predicted the bulk band structure of nine III-V semiconductors in wurtzite phase.Here, we predict the frequency dependent dielectric functions for nine non-Nitride wurtzite phase III-V semiconductors (AlP, AlAs, AlSb, GaP, GaAs, GaSb, InP, InAs and InSb). Their complex dielectric functions are calculated in the dipole approximation by evaluating the momentum matrix elements on a dense grid of special k-points using empirical pseudopotential wave functions. Corrections to the momentum matrix elements accounting for the missing core states are made using a scaling factor which is determined by using the optical sum rules on the calculated dielectric functions for the zincblende polytypes. The dielectric function is calculated for polarizations perpendicular and parallel to the c-axis of the crystal.
Spatial configurations of the Warsaw Ghetto : selected aspects of Jewish space and Nazi policies
Creators: name: Nowak, Anja
Publisher: name: University of British Columbia
Year: 2021

description: Conceptualizing space as both a social product and a social agent, my thesis examines the Jewish ghetto that the Nazi German occupiers created in Warsaw in the years between 1940 and 1943 from a distinct spatial perspective. Following the example of authors such as Dan Stone, Anne Kelly Knowles, Tim Cole, Alberto Giordano, Paolo Giaccaria and Claudio Minca, my study, thus, makes a case for the relevance of spatial analysis in the context of the Holocaust. Seeing the ghetto itself as a form of violence exerted against the Jews, I proceed in two steps: In the first part of the study, I trace out which German policies and actions created and shaped the space of the ghetto and how it changed over time due to shifts in the Nazi German agenda and the practices on site. The analysis is guided by the objective of making transparent the administrative processes and responsibilities involved in the ghetto’s creation and management. At the same time, the analysis pursues questions regarding violence, power dynamics, segregation, spatial appropriation and ownership, identity-formation, as well as social, cultural and economic exclusion. In the second part of the study, I shift the focus to explore the space of the ghetto as it was perceived, experienced and described by the people held within it. Building largely on war-time diaries and post-war memoirs, the study investigates particular examples, constellations and recurring situations to further explore how the spatial environment – both in its physical and social dimensions – negatively affected Jewish everyday life, cultural practices, social and personal identity-formation and social relationships. By showing that the ghetto space was inherently adverse to Jewish life, I will advocate a view of the ghetto that emphasizes the violent nature of the spatial environment itself. The analysis of the observations from first-hand accounts is based on concepts and terminology from a broad range of theoretical approaches from the fields of history, urban studies, architecture, (human) geography, anthropology, political theory, philosophy, and sociology, making the study inherently interdisciplinary.
Not Quite this and not Quite that: Anorexia Nervosa, Counselling Psychology, and Hermeneutic Inquiry in a Tapestry of Ambiguity
Creators: name: Williams, Emily P
name: Russell-Mayhew, Shelly
name: Moules, Nancy J
name: Dimitropoulos, Gina
Publisher: name: University of Calgary
Year: 2018
Subjects: ambiguity; anorexia nervosa; hermeneutic inquiry; counselling psychology

description: As a group of researchers exploring how to best understand the complex topic of families discovering their loved one has anorexia nervosa (AN), we found that we had to weave ambiguity into our design. Embracing ambiguity allowed us to create a tapestry that acknowledges the ambiguity of AN, counselling psychology (and other helping professions), and hermeneutic inquiry. In fact, the “not quite this and not quite that” features of these three constructs emerged as the thread that holds the inquiry together. We review the topic of AN through a lens of ambiguity.  Further, we position both the field of counselling psychology and the research method of hermeneutic inquiry as compatible frameworks in the study of AN, in both practice and research. By acknowledging, and at times even embracing, ambiguity, we respect the complexity of the situation we are studying.
description: Journal of Applied Hermeneutics, 2018
Copia de informaciones de hidalguía y limpieza de sangre de Roque González Manzanares
Creators: name: González Manzanares, Roque¬Manzanares, Ana de
Publisher: name: Universidad del Rosario
Year: 1645

description: Copia del siglo XIX de las informaciones de Roque González Manzanares, solicitadas en 1656 por su madre Ana de Manzanares a la escribanía de Pedro Tenorio. Las informaciones se habían realizado para acreditar la hidalguía y limpieza de sangre de Roque González ante el Rey de España para ofrecer sus servicios en Las Indias, Italia o en Flandes. Incluye la solicitud a la escribanía de Pedro Tenorio, escribano fallecido. El expediente contiene copias de los interrogatorios, la fe de bautismo y confirmación católica.
Stellar adiabatic mass loss model and applications
Creators: name: Ge, Hongwei
name: Webbink, Ronald F.
name: Han, Zhanwen
name: Chen, Xuefei
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Roche-lobe overflow and common envelope evolution are very important in binary evolution, which is believed to be the main evolutionary channel to hot subdwarf stars. The details of these processes are difficult to model, but adiabatic expansion provides an excellent approximation to the structure of a donor star undergoing dynamical time scale mass transfer. We can use this model to study the responses of stars of various masses and evolutionary stages as potential donor stars, with the urgent goal of obtaining more accurate stability criteria for dynamical mass transfer in binary population synthesis studies. As examples, we describe here several models with the initial masses equal to 1 Msun and 10 Msun, and identify potential limitations to the use of our results for giant-branch stars.
description: 7 pages, 5 figures,Accepted for publication in AP&SS, Special issue Hot Sub-dwarf Stars, in Han Z., Jeffery S., Podsiadlowski Ph. eds
Escritura de venta del esclavo Juan Moyano al rector del Colegio Mayor del Rosario
Creators: name: Pineda, Francisco Mariano de¬Moyano, Francisco¬Caldas, María¬Alarcón  y Castro, Agustín Manuel de
Publisher: name: Universidad del Rosario
Year: 1782

description: Poder concedido a Mariano Pineda por María Eugenia de Caldas y su hijo Francisco Moyano, para vender  a un esclavo mulato de 14 años llamado Juan Moyano. El expediente continúa con el registro de la venta del esclavo al rector del Colegio Mayor del Rosario Agustín Manuel de Alarcón.
Perfect absorption and giant magnification with a thin metamaterial layer
Creators: name: Jin, Y.
name: Xiao, S. S.
name: Mortensen, N. A.
name: He, S. L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: It is shown that perfect absorption and giant amplification can be realized when a wave impinges on a special metamaterial layer with zero real parts of the permittivity and permeability. The imaginary parts of the permittivity and permeability remain nonzero, corresponding to finite loss or gain. Perfect absorption and giant magnification can still be achieved even if the thickness of the metamaterial layer is arbitrarily thin and the absolute imaginary parts of the permittivity and permeability are very small. The metamaterial layer needs a total-reflection substrate for perfect absorption, while this is not required for giant magnification.
description: 15 pages, 4 figures
Automatic Determination of Stellar Atmospheric Parameters and Construction of Stellar Spectral Templates of the Guoshoujing Telescope (LAMOST)
Creators: name: Wu, Yue
name: Luo, A-Li
name: Li, Haining
name: Shi, Jianrong
name: Prugniel, Philippe
name: Liang, Yanchun
name: Zhao, Yongheng
name: Zhang, Jiannan
name: Bai, Zhongrui
name: Wei, Peng
name: Dong, Weixiang
name: Zhang, Haotong
name: Chen, Jianjun
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: A number of spectroscopic surveys have been carried out or are planned to study the origin of the Milky Way. Their exploitation requires reliable automated methods and softwares to measure the fundamental parameters of the stars. Adopting the ULySS package, we have tested the effect of different resolutions and signal-to-noise ratios (SNR) on the measurement of the stellar atmospheric parameters (effective temperature Teff, surface gravity log g, and metallicity [Fe/H]). We show that ULySS is reliable to determine these parameters with medium-resolution spectra (R~2000). Then, we applied the method to measure the parameters of 771 stars selected in the commissioning database of the Guoshoujing Telescope (GSJT). The results were compared with the SDSS/SEGUE Stellar Parameter Pipeline (SSPP), and we derived precisions of 167 K, 0.34 dex, and 0.16 dex for Teff, log g and [Fe/H] respectively. Furthermore, 120 of these stars are selected to construct the primary stellar spectra template library (Version 1.0) of GSJT, and will be deployed as basic ingredients for the GSJT automated parametrization pipeline.
description: 23 pages, 15 figures, accepted by RAA
Escrituras de compra, venta y réditos de una casa en la ciudad de Cartagena
Creators: name: Lara, Pedro
Publisher: name: Universidad del Rosario
Year: 1824

description: Documentos de compra, venta y pago de réditos de una casa en la ciudad de Cartagena de Indias. 1. (fol. 15-16) Escritura de 1851 de venta de una casa en el barrio o parroquia de la Trinidad en la ciudad de Cartagena de Indias por Juan Eckart a Ciprian Julio. 2. (fol. 17- 18) Escritura de 1848 queda cuenta del remate de la casa en el barrio o parroquia de Trinidad perteneciente a Antonia Rubio. 3.  (fol. 19-25) Escritura de 1844 sobre la deuda de Manuel de Jesús Buendía sobre la casa ubicada en la calle del espíritu santo de la parroquia de la Trinidad en Cartagena, y registro del subsiguiente acto público de remate de la propiedad comprada por Juan Eckart. Se exponen los réditos que debían ser pagados a distintas instituciones. 4. (fol. 27-34) Expediente sobre el traslado de un préstamo (censo) por parte de Manuel de Jesús Buendía,  aplicado sobre una casa baja de la plaza del matadero de Cartagena de Indias a otra casa ubicada en el calle del Espíritu santo de la misma ciudad.
Der Verein MiKK e.V. – Mediator: innen und Dialog ohne Grenzen
Creators: name: Jańczuk, Magdalena
Publisher: name: E-Wydawnictwo. Prawnicza i Ekonomiczna Biblioteka Cyfrowa. Wydział Prawa, Administracji i Ekonomii Uniwersytetu Wrocławskiego
Year: 2021

description: MiKK – International Mediation Centre for Family Conflict and Child Abduction, is the leading international specialist in the field of cross-border family mediation. MiKK is an internationally recognized, neutral and independent NGO based in Berlin. For almost 20 years MiKK has been helping families from all over the world to find amicable solutions on all issues surrounding international custody disputes as well as child abduction cases. MiKK sets up and organizes multi-lingual mediations in any country for parents who wish to try and resolve their dispute by way of mediation in the best interest of their child. Courts, Lawyers, Embassies, Ministries of Justice/Central Authorities from all over the world refer parents to MiKK. MiKK also trains mediators in the field of cross-border family mediation and arranges the first contact between mediators and parents. There are currently more than 170 multilingual mediators worldwide who mediate in more than 30 languages. This article gives an overview and important information about MiKK’s work. It will also present the organisational solutions developed by the organisation that could be replicated in other European countries. It briefly describes MiKKs cooperation and referral of mediators as well as the organisation’s cooperation with national and international authorities.
Cuentas de las rentas de las propiedades del Colegio Mayor del Rosario en Cartagena
Creators: name: Berrio y Mendoza, Luis Antonio de
Publisher: name: Universidad del Rosario
Year: 1726

description: Joseph Martínez Caballero administrador de las rentas del Colegio Mayor del Rosario en la ciudad de Cartagena, entrega las cuentas de ingresos y gastos que se han realizado durante su administración. El informe de cuentas presenta los reportes de finales de 1726  hasta  1731.
Online Dispute Resolution : powszechny instrument rozstrzygania sporów konsumenckich?
Creators: name: Piwowarczyk, Marika
Publisher: name: E-Wydawnictwo. Prawnicza i Ekonomiczna Biblioteka Cyfrowa. Wydział Prawa, Administracji i Ekonomii Uniwersytetu Wrocławskiego
Year: 2021

description: The study concerns the European electronic platform for resolving consumer disputes, so-called ODR platform. The aim of the study is to analyse the conditions for the use of the ODR platform and to verify whether it is a common legal remedy in the scope of consumer protection. The aim of the European ODR platform was to facilitate access to simple, effective, quick, easy and cheap methods of resolving disputes between consumers and entrepreneurs arising from the online sale of goods and services. This study analyses whether the above assumptions are completed and whether the ODR platform has any impact on the consumer protection system in the European Union.
Direct measurement of the flow field around swimming microorganisms
Creators: name: Drescher, Knut
name: Goldstein, Raymond E.
name: Michel, Nicolas
name: Polin, Marco
name: Tuval, Idan
Publisher: name: arXiv
Year: 2010
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Swimming microorganisms create flows that influence their mutual interactions and modify the rheology of their suspensions. While extensively studied theoretically, these flows have not been measured in detail around any freely-swimming microorganism. We report such measurements for the microphytes Volvox carteri and Chlamydomonas reinhardtii. The minute ~0.3% density excess of V. carteri over water leads to a strongly dominant Stokeslet contribution, with the widely-assumed stresslet flow only a correction to the subleading source dipole term. This implies that suspensions of V. carteri have features similar to suspensions of sedimenting particles. The flow in the region around C. reinhardtii where significant hydrodynamic interaction is likely to occur differs qualitatively from a "puller" stresslet, and can be described by a simple three-Stokeslet model.
description: 4 pages, 4 figures, accepted for publication in PRL
Tryby rozstrzygania sporów inwestycyjnych ze szczególnym uwzględnieniem arbitrażu zgodnie z regulacjami Konwencji ICSID
Creators: name: Trnka, Krzysztof
Publisher: name: E-Wydawnictwo. Prawnicza i Ekonomiczna Biblioteka Cyfrowa. Wydział Prawa, Administracji i Ekonomii Uniwersytetu Wrocławskiego
Year: 2021

description: Arbitration, as a method of settling investor-state disputes, generates quite a lot of controversy. It is seen as a way for private entities to circumnavigate the legal system and to secure concessions from states, often to the detriment of ordinary citizens. This paper analyzes investor-state arbitration in the European Union, utilizing statistical data published by the International Center for Settling Investment Disputes. As it turns out, the outcomes of arbitration are more often than not favourable to EU member-states. Noteworthy is also the effectiveness, with which EU-based investors use arbitration in their disputes with non-EU states.
Mechanisms of treatment induced cell plasticity in prostate cancer
Creators: name: Thaper, Daksh
Publisher: name: University of British Columbia
Year: 2019

description: While effective, resistance to 1st generation and 2nd generation androgen receptor (AR) pathway inhibitors is inevitable, creating a need to study the mechanisms by which prostate cancer (PCa) cells become resistant to these treatments. At its core, resistance can be categorized into AR driven and non-AR driven. The research presented in this thesis explores the hypothesis that non-AR driven resistance mechanisms exploit cellular plasticity to gain a survival advantage. Previous research has demonstrated that in response to 1st generation anti-androgens, epithelial PCa cells can undergo an epithelial-mesenchymal transition (EMT); a process implicated in metastatic dissemination of cancer cells throughout the body. Augmenting prior research demonstrating LYN tyrosine kinase’s role in resistance to 1st generation anti-androgens, our research demonstrates LYN promoting both EMT and metastasis. Specifically, we discovered that signaling cascade downstream of LYN alters the sub-cellular localization and therefore stability of key EMT promoting transcription factors Slug and Snail. While LYN does contribute to both treatment resistance and metastasis in PCa, its role in EMT was a pan-cancer mechanism observed in both breast and bladder cancer. Our research also explored the increased incidence of neuroendocrine PCa (NEPC) as a resistance mechanism to more potent 2nd generation anti-androgens (enzalutamide and abiraterone). Interrogating a model of in vivo derived enzalutamide resistance, our research uncovered the crucial role of neuronal transcription factor brain derived 2 (BRN2) in the transformation of epithelial prostate cells to neuroendocrine (NE) phenotype. Importantly, we discovered that AR inhibition relives its’ suppression of BRN2; thereby increasing BRN2 expression and initiating NE differentiation of epithelial PCa cells. Moreover, targeting BRN2 not only reduced the enzalutamide-induced NE differentiation but also reduced proliferation of enzalutamide resistant PCa cells and terminal NEPC cells. Building on this data, our research outlines the discovery of small molecule BRN2 inhibitors (BRN2i) that recapitulate the functional results demonstrated by conventional knockdown techniques. These BRN2i display specificity to BRN2 and selectivity in compromising growth of NEPC cells. Altogether, this thesis demonstrates two possible mechanisms how PCa cells alter their identity as epithelial cells to more mesenchymal (LYN) and/or neuroendocrine (BRN2) and gain resistance to AR pathway inhibitors.
Megaselia aliusalius Disney & Durska 2020, sp. nov.
Creators: name: Disney, R. Henry L.
name: Durska, Ewa
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Phoridae
Megaselia
Megaselia aliusalius

description: Megaselia aliusalius Disney, sp. nov. (Figs 1–9) Description. (Male). In the key to the males of the species of Megaselia recorded from the British Isles (Disney 1989), with constant intermediates between choices, it runs to couplets 192, 200, 242 lead 2, 211, 213 and 220 lead 1. All options are excluded, along with subsequently added species running to these couplets, by details of the hypopygium along with features such as only 2 notopleural bristles and/or all brown legs and/or a longer costal index. In Borgmeir’s (1966) key to Nearctic Group VIII it runs to couplet 11 lead 2, but is likewise excluded. It fails to key out in the rest of the world’s fauna. Male. Note, the front legs are missing in the only specimen available. Frons as Fig. 1, without fine microtrichia. Cheek with 4 bristles and jowl with 2 that are longer and more robust. Postpedicels, without SPS vesicles, palps and proboscis as Fig. 2, the labella lacking short spinules below. Thorax brown, with 3 notopleural bristles, with no cleft in front of these, and mesopleuron bare (Fig. 3). Scutellum with an anterior pair of small hairs and a posterior pair of bristles. Abdominal tergites and venter as Fig. 4, the latter with small hairs on segments 3–6. Hypopygium as Figs 5–7. Legs yellowish brown to dusky yellow. Dorsal hair palisade of mid tibia extends about 0.61 times its length. Hairs below basal half of hind femur about as long as those of anteroventral row of outer half (Fig. 8). Hind tibia with at most a dozen only moderately differentiat- ed posterodorsal hairs, without anterodorsals and spinules of apical combs simple. Wings (Fig. 9) 1.06 mm long. Costal index 0.39. Costal ratios with 1 clearly longer than 2+3 and 2 longer than 3. Costal cilia 0.11 m long. Vein 3 hair 0.02–0.03 mm long. 3 axillary bristles, the outermost being 0.09 mm long. Sc not reaching R1. Haltere knob pale.  Type material. Holotype male, Poland, Wigry National Park, in emergence trap in plot 5 with Impatients parviflora DC, IX. 2017, E. Durska leg. (MIZ PAS, – 28–61). Etymology. Named after being yet another (alius) new species and repeated as there is already an Australian species M. alius Disney.
description: Published as part of Disney, R. Henry L. & Durska, Ewa, 2020, New Species And New Records Of Megaselia Rondani (Insecta: Diptera: Phoridae) From Wigry National Park (Poland), pp. 97-108 in Annales Zoologici 70 (1) on pages 97-98, DOI: 10.3161/00034541ANZ2020.70.1.004, http://zenodo.org/record/3776722
description: {"references": ["Disney, R. H. L. 1989. Scuttle Flies - Diptera Phoridae Genus Megaselia. Handbooks for the Identification of British Insects, 10 (8): 1 - 155."]}
Administration of communion to the sick by an extraordinary minister.
Creators: name: Catholic Church.
Publisher: name: University of Notre Dame
Year: 2023

description:
 Caption title.
 Administration of Communion to the Sick by an Extraordinary Minister, excerpted from Holy Communion and Worship of the Eucharist Outside of Mass, copyrighted 1974, International Committee on English in the Liturgy, Inc.--Page [1].
 Catholic pamphlet.
 Administration of Communion and Viaticum to the sick by an extraordinary Minister (U.S.)
Experience and Interpretation in Global Times: The Case of Special Education
Creators: name: Smith, David Geoffrey
Publisher: name: University of Calgary
Year: 2018
Subjects: hermeneutics; special education; research theory; invalid

description: This paper was delivered as a keynote address at the International Symposium for Qualitative Transformation of the Paradigm of Educational Practice and Special Education, Busan National University, South Korea, April 16, 2006. The symposium was sponsored by The Korean Research Society for Phenomenological and Hermeneutic Practice, and the Research Institute for Special Education of Busan National University.
description: Journal of Applied Hermeneutics, 2018
Mandatory mediation in family disputes in Lithuania: model and first year application experience
Creators: name: Tvaronavičienė, Agnė
name: Intė, Odeta
Publisher: name: E-Wydawnictwo. Prawnicza i Ekonomiczna Biblioteka Cyfrowa. Wydział Prawa, Administracji i Ekonomii Uniwersytetu Wrocławskiego
Year: 2021

description: Jednym z najważniejszych dotychczas etapów rozwoju mediacji na Litwie stało się wprowadzenie obowiązkowej mediacji w sprawach rodzinnych. W opracowaniu opisano model obowiązkowej mediacji przyjęty na Litwie oraz omówiono skutki jego wprowadzenia, które dało się zaobserwować w ciągu roku od jego wejścia w życie, ponadto zidentyfikowano największe wyzwania tego modelu. Elastyczny model mediacji wprowadzony na Litwie wymaga od strony zamierzającej wszcząć postępowanie sądowe uprzedniego rozpoczęcia obowiązkowego postępowania mediacyjnego. Druga strona sporu ma możliwość wyboru – albo przystąpienia do mediacji, albo odrzucenia tej propozycji. Nadto, koszt obowiązkowej mediacji w sprawach rodzinnych jest pokrywany ze środków budżetowych. Doświadczenia pierwszego roku obowiązywania przepisów wprowadzających obowiązkową mediację w sprawach rodzinnych pokazują, że pomimo wysokiego odsetka mediacji zakończonych ugodą ponad połowa spraw objętych zakresem stosowania obowiązkowej mediacji nie dociera do etapu spotkań z mediatorem, kończąc się odmową udziału w mediacji przez drugą stronę. Z uwagi na dopuszczoną w przepisach możliwość przystąpienia do mediacji albo odrzucenia udziału w niej wiele stron korzysta z tej drugiej możliwości. Dotychczasowa praktyka pokazała również inne luki w obecnej regulacji obowiązkowej mediacji w sprawach rodzinnych, takie jak: nieostry katalog spraw, które podlegają obowiązkowej mediacji, brak odpowiednich reguł mających chronić najlepszy interes małoletnich czy dopuszczających wysłuchanie małoletnich dzieci w procesie mediacji. Niedoskonałość obecnych przepisów regulujących obowiązkową mediację skutkuje m.in. tym, że w niektórych transgranicznych postępowaniach w sprawach rodzinnych strona litewska przegrywa spór o ustalenie jurysdykcji. Ponadto, niskie stawki godzinowe przewidziane dla mediatorów prowadzących mediację finansowaną ze środków budżetowych skutkują spadkiem ich motywacji z uwagi na niskie wynagrodzenie za wykonaną pracę. Nakreślone wyżej wyzwania, będące konsekwencją obecnie przyjętego na Litwie modelu obowiązkowej mediacji w sprawach rodzinnych, stanowią przeszkodę na drodze jego pełnej skuteczności.
Guest Editorial: "It's February. It Won't Last"
Creators: name: Jardine, David W
Publisher: name: University of Calgary
Year: 2018
Subjects: hermeneutics, Buddhism, grief, suffering, interpretation

description: The following small reflection was written around a year ago, but it has taken on new urgency for me with Nancy Moules’ (2017) and Kate Beamer’s (2017) writing late last year, and my own more recent (Jardine, 2018), slightly unexpected response.
description: Journal of Applied Hermeneutics, 2018
Mediar y remediar: la mediación como profesión y como procedimiento para gestionar conflictos en España
Creators: name: Alcaide, Carlos Villagrasa
Publisher: name: E-Wydawnictwo. Prawnicza i Ekonomiczna Biblioteka Cyfrowa. Wydział Prawa, Administracji i Ekonomii Uniwersytetu Wrocławskiego
Year: 2021

description: Mediacja jest coraz częściej wybieraną alternatywą w zawodach prawniczych jako ścieżka kariery po studiach i szkoleniach podyplomowych. Jest także opcją dla zarządzania konfliktami z uwagi na swoje zalety, do których należy znaczna autonomia stron w rozwiązywaniu konfliktu, przynajmniej w porównaniu z innymi opcjami, dającymi stronom mniejsze możliwości odpowiedzialnego i suwerennego podejmowania decyzji o własnym życiu i o relacjach międzyludzkich. Ale mediacja to nie tylko zawód nabyty po wyższym i specjalistycznym przeszkoleniu w zakresie technik ułatwiania dialogu i zarządzania pokojową komunikacją. Jest to idealny sposób na promowanie demokratycznego współistnienia i poszanowania różnorodności, dlatego coraz ważniejsze jest podkreślanie jego stosowania i promowanie mediacji także wśród dzieci i młodzieży. Istotne jest, by już od najmłodszych lat rozwijać świadomość własnych praw i respektować je. Ważne jest, aby w procesie stopniowego uczenia się dzieci nabywały kompetencje społeczne, które będą umożliwiały w przyszłości, ale też obecnie, rozwiązywanie sporów m.in. dotyczących ich własnego życia. To pokojowa droga do promowania równości naszych systemów demokratycznych.
Carta de Benito Osorio donde solicita autorización para los siguientes certámenes de medicina
Creators: name: Osorio, Benito¬Castillo y Rada, José María del
Publisher: name: Universidad del Rosario
Year: 1833

description: Carta del catedrático Benito Osorio al rector del Colegio del Rosario pidiendo autorización para dedicarle el siguiente certamen de la cátedra de medicina
Neurasthenia Revisited: On Medically Unexplained Syndromes and the Value of Hermeneutic Medicine
Creators: name: Aho, Kevin
Publisher: name: University of Calgary
Year: 2018
Subjects: neurasthenia, fibromyalgia, chronic fatigue syndrome, somatization, naturalism, hermeneutics

description: The rise of medically unexplained conditions like fibromyalgia and chronic fatigue syndrome in the United States looks remarkably similar to the explosion of neurasthenia diagnoses in the late nineteenth century. In this paper, I argue the historical connection between neurasthenia and today’s medically unexplained conditions hinges largely on the uncritical acceptance of naturalism in medicine. I show how this cultural acceptance shapes the way in which we interpret and make sense of nervous distress while, at the same time, neglecting the unique social and historical forces that continue to produce it. I draw on the methods of hermeneutic philosophy to expose the limits of naturalism and forward an account of health and illness that acknowledges the extent to which we are always embedded in contexts of meaning that determine how we experience and understand our suffering.
description: Journal of Applied Hermeneutics, 2018