cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of Physicians’ knowledge on specific rare diseases and its associated factors: a national cross-sectional study from China
Creators: name: Zhang, Huanyu
name: Xiao, Ying
name: Zhao, Xinyue
name: Tian, Zhuang
name: Zhang, Shu-yang
name: Dong, Dong
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 1. List of knowledge questions and answers based on 34 rare diseases of concern.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0693
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0693, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0693, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Phylogenetic analysis of multiprobe fluorescence in situ hybridization data from tumor cell populations.
Creators: name: Chowdhury, Salim A.
name: Shackney, Stanley E.
name: Heselmeyer-Haddad, Kerstin M.
name: Ried, Thomas
name: Schäffer, Alejandro H.
name: Schwartz, Russell
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: MOTIVATION: Development and progression of solid tumors can be attributed to a process of mutations, which typically includes changes in the number of copies of genes or genomic regions. Although comparisons of cells within single tumors show extensive heterogeneity, recurring features of their evolutionary process may be discerned by comparing multiple regions or cells of a tumor. A useful source of data for studying likely progression of individual tumors is fluorescence in situ hybridization (FISH), which allows one to count copy numbers of several genes in hundreds of single cells. Novel algorithms for interpreting such data phylogenetically are needed, however, to reconstruct likely evolutionary trajectories from states of single cells and facilitate analysis of tumor evolution. RESULTS: In this article, we develop phylogenetic methods to infer likely models of tumor progression using FISH copy number data and apply them to a study of FISH data from two cancer types. Statistical analyses of topological characteristics of the tree-based model provide insights into likely tumor progression pathways consistent with the prior literature. Furthermore, tree statistics from the resulting phylogenies can be used as features for prediction methods. This results in improved accuracy, relative to unstructured gene copy number data, at predicting tumor state and future metastasis. AVAILABILITY: Source code for software that does FISH tree building (FISHtrees) and the data on cervical and breast cancer examined here are available at ftp://ftp.ncbi.nlm.nih.gov/pub/FISHtrees. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Fast quantum state engineering via universal SU(2) transformation
Creators: name: Huang, Bi-Hua
name: Kang, Yi-Hao
name: Chen, Ye-Hong
name: Wu, Qi-Cheng
name: Song, Jie
name: Xia, Yan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We introduce a simple yet versatile protocol to inverse engineer the time-dependent Hamiltonian in two- and three level systems. In the protocol, by utilizing a universal SU(2) transformation, a given speedup goal can be obtained with large freedom to select the control parameters. As an illustration example, the protocol is applied to perform population transfer between nitrogen-vacancy (NV) centers in diamond. Numerical simulation shows that the speed of the present protocol is fast compared with that of the adiabatic process. Moreover, the protocol is also tolerant to decoherence and experimental parameter fluctuations. Therefore, the protocol may be useful for designing an experimental feasible Hamiltonian to engineer a quantum system.
description: 11 pages, 8 figures, has been accepted by Physical Review A
Linum flavum Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Linaceae
Linum
Linum flavum

description: Linum flavum Linnaeus, Species Plantarum 1: 279. 1753.
"Habitat in Austria." RCN: 2215.
 Lectotype (Optasyuk & Jarvis in Optasyuk & Mosyakin, Ukrainian Bot.J. 63: 525, f. [525]. 2006): Herb. Burser XII: 37 (LINN).
 Current name: Linum flavum L. (Linaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 634, DOI: 10.5281/zenodo.291971
Understanding the saturation of proton-driven Weibel instabilities and implications for astrophysics
Creators: name: Ren, Chuang
name: Blackman, Eric G.
name: Fong, Wen-fai
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The linear growth rate and saturation level of magnetic fields for Weibel instabilities driven by ion temperature anisotropy, defined as $α=(T_\perp/T_\parallel)-1$ where $T_\perp$ and $T_\parallel$ are ion temperatures perpendicular and parallel to the wave vector, are derived in the small $α$-limit. It is shown that the ratio of the saturated magnetic energy to the initial ion energy scales as the fourth power of the electron to ion mass ratio, $m/M$, for an initially unmagnetized plasma with $α\leq M/m$. Particle-in-cell simulations confirm the mass scaling and also show that the electron energy gain is of the same order of magnitude as the magnetic field energy. This implies that the Weibel instabilities cannot provide a faster-than-Coulomb collisionless mechanism to equilibrate ion-electron plasmas with ions initially much hotter than electrons, a key component in low-luminosity astrophysical accretion flows. The results here also show that the large $α$-limit formulae used in the study of magnetic field generation in collisionless shocks are only valid if $α\geq M/m$.
description: revised version, 10 pages, including 3 figs., in press, Physics of Plasmas
title: ADCO, Grènetier de Cîteaux : comptes (1497-1504) (11 H 1172), f. 00069
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172), f. 00069, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
pHMA, a pH-sensitive GFP reporter for cell engulfment, in Drosophila embryos, tissues, and cells.
Creators: name: Elane  Fishilevich
name: Fitzpatrick, James
name: Minden, Jonathan
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Engulfment of apoptotic cells by phagocytosis ensures the removal of unwanted and defective cells. We developed a genetically encoded marker for cell engulfment, pHMA, which consists of the pH-Sensitive derivative of GFP, pHluorin, fused to the actin-binding domain of Moesin. In healthy cells of Drosophila embryos and cultured cells, pHMA resides at the cell cortex. In dying cells, pHMA loses its cortical localization and reports a modest decrease in pH. In embryos, the dying cells lose their apical contacts, then move basally and are ultimately engulfed by neighboring cells or macrophages. The cell corpse material is strongly acidified soon after engulfment and persists in the phagocytic cell for several hours. Changes in the pHMA signal correlate well with increases or decreases in apoptosis. These data show that pHMA is a useful reporter for cell engulfment and can be used in screening for mutations that affect cell engulfment.
An Appearance-Like Reactor Experiment To Measure Ue3
Creators: name: Bernabeu, Jose
name: Palomares-Ruiz, Sergio
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Conventional reactor neutrino experiments are dissapearance experiments, and thus have less sensitivity to small mixing angles than appearance experiments do. It has been recently shown that future reactor neutrino experiments consisiting of a near and far detector are competitive with first-generation superbeams in order to determine sin^2{2 theta_{13}} down to 10^{-2}. We show that by using the antineutrino-electron elastic scattering at the near detector around the configuration where dsigma^{barν_e}/dT presents a dynamical zero, an appearance-like experiment can be simulated, with a sensitivity comparable to the one achieved with the inverse beta-decay reaction in the far detector. Thus, the near detector could also be used to look for oscillations. We present how antineutrino-electron elastic scattering could be properly used for this purpose allowing that the combination of the measurements in the far detector and in the near detector would push the sensitivity of the experiment to a lower value of theta_{13}.
description: 18 pp., 6 figs
Linkages between Outdoor Learning in early years and primary education with recreational visits to the outdoors as young adults:  A narrative literature review
Creators: name: MacLean, Laura
name: Marshall, Acacia
name: Conniff, Anna
name: Somervail, Phoebe
name: Irvine, Katherine N.
Publisher: name: Zenodo
Year: 2023
Subjects: outdoor learning
recreational visits to outdoors

description: This report considers the potential for linkages between outdoor learning by pre-school and primary age pupils (3-12 year olds) with subsequent recreational visits to the outdoors by secondary school aged children and young adults. Scotland's Curriculum for Excellence seeks to ensure that all children will experience outdoor learning. Given this, an understanding of the impact that outdoor learning has across the life course can assist policymakers in developing effective early years and outdoor education and outdoor learning policy.
This work was funded by Scottish Government under the Rural & Environment Science & Analytical Services Division 2022-2027 (project number JHI-C6-1).
QCD Physics Opportunities in Low-Energy Electron-Positron Annihilation
Creators: name: Brodsky, S. J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I survey a number of interesting tests of quantum chromodynamics at the amplitude level which can be carried out in electron-positron annihilation and in photon-photon collisions at low energy, including measurements of fundamental processes such as timelike form factors and transition amplitudes, timelike Compton scattering, timelike photon to meson transition amplitudes, and two-photon exclusive processes. Many of these reactions test basic principles of QCD such as hadronization at the amplitude level, factorization, and hadron helicity conservation, tools also used in the analysis of exclusive $B$ and $D$ decays. Measurements of the final-state polarization in hadron pair production determine the relative phase of the timelike form factors. The role of two-photon exchange amplitudes can be tested using the charge asymmetry of the $e^+ e^- \to B \bar B$ processes. Precision measurements of the electron-positron annihilation cross section can test the generalized Crewther relation and determine whether the effective couplings defined from physical measurements show infrared fixed-point and near conformal behavior. I also discuss a number of tests of novel QCD phenomena accessible in $e^+ e^-$ annihilation, including near-threshold reactions, the production of baryonium, gluonium states, and pentaquarks.
description: 20 pages, 15 figures. Invited talk at the Workshop on e+e- in the 1-2 GeV Range, Alghero, Italy, September 2003 (eConf C0309101)
Climate4impact: Enhance usage of research data and support researchers with climate analysis
Creators: name: Plieger, Maarten
name: Som de Cerff, Wim
name: Spinuso, Alessandro
name: De Vreede, Ernst
name: Pagé, Christian
name: Drost, Niels
Publisher: name: Zenodo
Year: 2019

description: The aim of climate4impact (C4I) is to enhance the use of research data, to support researchers with analytics and
 to support other climate portals. It is currently under development within the European Project IS-ENES3 and
 builds on previous developments from IS-ENES2, CLIPC and C3S-Magic. C4I utilizes the globally distributed
 ESGF web services as data source, it uses ESGF search, Opendap and Thredds catalogs. C4I offers web interfaces
 for searching, visualizing, analyzing, processing and downloading (climate) datasets and is targeted to climate
 impact researchers. As the climate impact community is very broad, the focus is mainly on the scientific impact
 community. This work has resulted in the ENES portal interface for climate impact communities and can be
 visited at https://climate4impact.eu.
 Dedicated wizards for processing of climate indices are developed in close collaboration with users. Processing
 services include climate indicator calculations, country based statistics and polygon extraction. C4I makes
 use of the DKRZ Birdhouse framework, which is an extendable and modular processing framework based on
 PyWPS. Data is obtained from various ESGF nodes using secure OpenDAP. C4I provides a personal basket where
 users can upload their own data and do research with the provided tools. The basket supports scientific data formats
 like NetCDF, GeoJSON and CSV. The basket has an access token mechanism to make data sharing with others and
 command line access to web services easier. Processing results become available in a personal basket. Datasets
 stored in the basket can be visualized and used in follow up processing tasks. The orchestration of security, basket
 and services is achieved using the ADAGUC-services framework, offering endpoints of Web Processing Services,
 Web Map and Web Coverage services. The software is open, reusable, modular and packaged. Components are
 available via docker containers to enable easy re-use.
 In the IS-ENES3 project, the web portal will be redesigned, building on experience gained during the previous
 projects. The next version of the portal will be built using the React framework, which allows for creating
 large web applications which can change data, without reloading the page. The main purpose of React is to be
 fast, scalable, and simple. This phase provides opportunities for users to provide another round of feedback.
 The climate analytics capabilities, the provided open source tools and the redesign plans are detailed in this
 presentation.
description: EGU 2019
Linum trigynum Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Linaceae
Linum
Linum trigynum

description: Linum gallicum Linnaeus, Species Plantarum, ed. 2, 1: 401. 1762, nom. illeg.
"Habitat Monspelii." RCN: 2210.
 Replaced synonym: Linum trigynum L. (1753).
 Lectotype (Siddiqi in Jafri & El-Gadi, Fl. Libya 35: 4. 1977): Herb. Linn. No. 396.19 (LINN).
 Current name: Linum trigynum L. (Linaceae).
 Note: A. superfluous name for L. trigynum L. (1753).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 634, DOI: 10.5281/zenodo.291971
Phenotypic signatures arising from unbalanced bacterial growth.
Creators: name: Cheemeng  Tan
name: Smith, Robert Phillip
name: Ming-Chi  Tsai
name: Schwartz, Russell
name: Lingchong  You
Publisher: name: Carnegie Mellon University
Year: 2014
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Fluctuations in the growth rate of a bacterial culture during unbalanced growth are generally considered undesirable in quantitative studies of bacterial physiology. Under well-controlled experimental conditions, however, these fluctuations are not random but instead reflect the interplay between intra-cellular networks underlying bacterial growth and the growth environment. Therefore, these fluctuations could be considered quantitative phenotypes of the bacteria under a specific growth condition. Here, we present a method to identify "phenotypic signatures" by time-frequency analysis of unbalanced growth curves measured with high temporal resolution. The signatures are then applied to differentiate amongst different bacterial strains or the same strain under different growth conditions, and to identify the essential architecture of the gene network underlying the observed growth dynamics. Our method has implications for both basic understanding of bacterial physiology and for the classification of bacterial strains.
New Self-Similar Solutions of Polytropic Gas Dynamics
Creators: name: Lou, Yu-Qing
name: Wang, Wei-Gang
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We explore semi-complete self-similar solutions for the polytropic gas dynamics involving self-gravity under spherical symmetry, examine behaviours of the sonic critical curve, and present new asymptotic collapse solutions that describe `quasi-static' asymptotic behaviours at small radii and large times. These new `quasi-static' solutions with divergent mass density approaching the core can have self-similar oscillations. Earlier known solutions are summarized. Various semi-complete self-similar solutions involving such novel asymptotic solutions are constructed, either with or without a shock. In contexts of stellar core collapse and supernova explosion, a hydrodynamic model of a rebound shock initiated around the stellar degenerate core of a massive progenitor star is presented. With this dynamic model framework, we attempt to relate progenitor stars and the corresponding remnant compact stars: neutron stars, black holes, and white dwarfs.
description: 17 pages, 11 figures, Accepted for publication in MNRAS
Physics holo.lab learning experience: Using Smartglasses for Augmented Reality labwork to foster the concepts of heat conduction
Creators: name: Strzys, M. P.
name: Kapp, S.
name: Thees, M.
name: Klein, P.
name: Lukowicz, P.
name: Knierim, P.
name: Schmidt, A.
name: Kuhn, J.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: Fundamental concepts of thermodynamics rely on abstract physical quantities such as energy, heat and entropy, which play an important role in the process of interpreting thermal phenomena and statistical mechanics. However, these quantities are not covered by human (visual) perception and thus, an intuitive understanding often is lacking. Today immersive technologies like head-mounted displays of the newest generation, especially HoloLens, allow for high quality augmented reality learning experiences, which can overcome this perception gap and simultaneously avoid a split attention effect. In a mixed reality (MR) scenario as presented in this paper---which we call a holo.lab---human perception can be extended to the thermal regime by presenting false-color representations of the temperature of objects as a virtual augmentation directly on the real object itself in real-time. Direct feedback to experimental actions of the users in form of different representations allows for immediate comparison to theoretical principles and predictions and therefore is supposed to intensify the theory-experiment interactions and to increase the conceptual understanding. We tested this technology for an experiment on thermal conduction of metals in the framework of undergraduate laboratories. A pilot study with treatment and control groups (N = 59) showed a small positive effect of MR on students' performance measured with a standardized concept test for thermodynamics, indicating an improvement of the understanding of the underlying physical concepts.
title: 01_0669
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
$^{13}$C isotopic fractionation of HC$_{3}$N in two starless cores: L1521B and L134N (L183)
Creators: name: Taniguchi, Kotomi
name: Ozeki, Hiroyuki
name: Saito, Masao
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We observed the $J=5-4$ rotational lines of the normal species and three $^{13}$C isotopologues of HC$_{3}$N at the 45 GHz band toward two low-mass starless cores, L1521B and L134N (L183), using the Nobeyama 45 m radio telescope in order to study the main formation pathways of HC$_{3}$N in each core. The abundance ratios of the three $^{13}$C isotopologues in L1521B are derived to be [H$^{13}$CCCN]:[HC$^{13}$CCN]:[HCC$^{13}$CN] = 0.98 (+- 0.14) : 1.00 : 1.52 (+- 0.16) (1 sigma). The fractionation pattern is consistent with that at the cyanopolyyne peak in Taurus Molecular Cloud-1. This fractionation pattern suggests that the main formation pathway of HC$_{3}$N is the neutral-neutral reaction between C$_{2}$H$_{2}$ and CN. On the other hand, their abundance ratios in L134N are found to be [H$^{13}$CCCN]:[HC$^{13}$CCN]:[HCC$^{13}$CN]= 1.5 (+- 0.2) : 1.0 : 2.1 (+- 0.4) (1 sigma), which are different from those in L1521B. From this fractionation pattern, we propose that the reaction between HNC and CCH is a possible main formation pathway of HC$_{3}$N in L134N. We find out that the main formation pathways of the same molecule are not common even in the similar physical conditions. We discuss the possible factors to make a difference in fractionation pattern between L134N and L1521B/TMC-1.
description: Accepted for publication in ApJ, 11pages, 4 figures, 2 tables
Pharmacological rescue of the mutant cystic fibrosis transmembrane conductance regulator (CFTR) detected by use of a novel fluorescence platform.
Creators: name: Holleran, John P.
name: Glover, Matthew L.
name: Peters, Kathryn W.
name: Bertrand, Carol A.
name: Watkins, Simon C.
name: Jarvik, Jonathan
name: Frizzell, Raymond A.
Publisher: name: Carnegie Mellon University
Year: 2012
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Numerous human diseases arise because of defects in protein folding, leading to their degradation in the endoplasmic reticulum. Among them is cystic fibrosis (CF), caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR ), an epithelial anion channel. The most common mutation, F508del, disrupts CFTR folding, which blocks its trafficking to the plasma membrane. We developed a fluorescence detection platform using fluorogen-activating proteins (FAPs) to directly detect FAP-CFTR trafficking to the cell surface using a cell-impermeant probe. By using this approach, we determined the efficacy of new corrector compounds, both alone and in combination, to rescue F508del-CFTR to the plasma membrane. Combinations of correctors produced additive or synergistic effects, improving the density of mutant CFTR at the cell surface up to ninefold over a single-compound treatment. The results correlated closely with assays of stimulated anion transport performed in polarized human bronchial epithelia that endogenously express F508del-CFTR. These findings indicate that the FAP-tagged constructs faithfully report mutant CFTR correction activity and that this approach should be useful as a screening assay in diseases that impair protein trafficking to the cell surface.
Continuity theorems for the $M/M/1/n$ queueing system
Creators: name: Abramov, Vyacheslav M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Probability (math.PR)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 60K25 (Primary) 60B05, 60E15, 62E17 (Secondary)

description: In this paper continuity theorems are established for the number of losses during a busy period of the $M/M/1/n$ queue. We consider an $M/GI/1/n$ queueing system where the service time probability distribution, slightly different in a certain sense from the exponential distribution, is approximated by that exponential distribution. Continuity theorems are obtained in the form of one or two-sided stochastic inequalities. The paper shows how the bounds of these inequalities are changed if further assumptions, associated with specific properties of the service time distribution (precisely described in the paper), are made. Specifically, some parametric families of service time distributions are discussed, and the paper establishes uniform estimates (given for all possible values of the parameter) and local estimates (where the parameter is fixed and takes only the given value). The analysis of the paper is based on the level crossing approach and some characterization properties of the exponential distribution.
description: Final revision; will be published as is
An Empirical Model of Packet Processing Delay of the Open vSwitch
Creators: name: Sattar, Danish
name: Matrawy, Ashraf
Publisher: name: arXiv
Year: 2017
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Network virtualization offers flexibility by decoupling virtual network from the underlying physical network. Software-Defined Network (SDN) could utilize the virtual network. For example, in Software-Defined Networks, the entire network can be run on commodity hardware and operating systems that use virtual elements. However, this could present new challenges of data plane performance. In this paper, we present an empirical model of the packet processing delay of a widely used OpenFlow virtual switch, the Open vSwitch. In the empirical model, we analyze the effect of varying Random Access Memory (RAM) and network parameters on the performance of the Open vSwitch. Our empirical model captures the non-network processing delays, which could be used in enhancing the network modeling and simulation.
Gravireggeons in Extra Dimensions and Interaction of Ultra-high Energy Cosmic Neutrinos with Nucleons
Creators: name: Kisselev, A. V.
name: Petrov, V. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the results on non-perturbative quantum gravity effects related to extra dimensions which can be comparable, in some cases, with the SM contributions, e.g. in lepton-lepton or lepton-nucleon scattering. The case of cosmic neutrino gravitational interaction with atmospheric nucleons is considered in detail.
description: 24 pages, LaTeX2e, references added, typos corrected
Einstein-Gauss-Bonnet theory of gravity: The Gauss-Bonnet-Katz boundary term
Creators: name: Deruelle, Nathalie
name: Merino, Nelson
name: Olea, Rodrigo
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a boundary term to the Einstein-Gauss-Bonnet action for gravity, which is constructed as the dimensional continuation of the Chern-Weil theorem, and such that the extremization of the full action yields the equations of motion when Dirichlet boundary conditions are imposed. When translated into tensorial language, this boundary term is the generalization to this theory of the Katz boundary term and vector for general relativity. The construction allows to deal with a general background and includes the Gibbons-Hawking-Myers boundary term as a special case, when the background is taken to be a product manifold. As a first application we show that this Einstein Gauss-Bonnet Katz action yields, without any extra ingredients or regularization, the expected mass of the Boulware-Deser black hole.
description: 13 pages
Linum hirsutum Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Linaceae
Linum
Linum hirsutum

description: Linum hirsutum Linnaeus, Species Plantarum 1: 277. 1753.
"Habitat in Austriae, Tatariae edits graminosis." RCN: 2207.
 Lectotype (Optasyuk in Optasyuk & Mosyakin, Ukrainian Bot. J. 63: 525, f. [524]. 2006): Gerber, Herb. Linn. No. 396.11 (LINN).
 Current name: Linum hirsutum L. (Linaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 634, DOI: 10.5281/zenodo.291971
Gravitational Waves, mu Term & Leptogenesis from B-L Higgs Inflation in Supergravity
Creators: name: Pallis, C.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a renormalizable extension of the minimal supersymmetric standard model endowed by an R and a gauged B - L symmetry. The model incorporates chaotic inflation driven by a quartic potential, associated with the Higgs field which leads to a spontaneous breaking of U(1)B-L, and yields possibly detectable gravitational waves. We employ quadratic Kahler potentials with a prominent shift-symmetric part proportional to c- and a tiny violation, proportional to c+, included in a logarithm with prefactor -N<0. It also offers an explanation of mu term of the MSSM provided that one related parameter in the superpotential is somewhat small. Baryogenesis occurs via non-thermal leptogenesis which is realized by the inflaton's decay to the lightest or next-to-lightest right-handed neutrino with masses lower than 1.8x10^13 GeV. Our scenario can be confronted with the current data on the inflationary observables, the baryon asymmetry of the universe, the gravitino limit on the reheating temperature and the data on the neutrino oscillation parameters, for 0.012<=c+/c-<1/N and gravitino as light as 1 TeV.
description: Published version. arXiv admin note: text overlap with arXiv:1312.3623
Visible spectroscopy of 2003 UB313: Evidence for N2 ice on the surface of the largest TNO?
Creators: name: Licandro, J.
name: Grundy, W. M.
name: Pinilla-Alonso, N.
name: de Leon, J.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The recent discovery of two large trans-Neptunian objects (TNOs) 2003 UB313 and 2005 FY9, with surface properties similar to those of Pluto, provides an exciting new laboratory for the study of processes considered for Pluto and Triton: volatile mixing and transport; atmospheric freeze-out and escape, ice chemistry, and nitrogen phase transitions. We studied the surface composition of TNO 2003 UB313, the first known TNO larger than Pluto. We report a visible spectrum covering the 0.35-0.95 microns spectral range, obtained with the 4.2m William Herschel Telescope at "El Roque de los Muchachos" Observatory (La Palma, Spain). The visible spectrum of this TNO presents very prominent absorpt- ions bands formed in solid CH4. At wavelengths shorter than 0.6 micron the spectrum is almost featureless and slightly red (S'=4%). The icy-CH4 bands are significantly stronger than those of Pluto and slightly weaker than those observed in the spectrum of another giant TNO, 2005 FY9, implying that methane is more abundant on its surface than in Pluto's and close to that of the surface of 2005 FY9. A shift of 15 +/-3 A relative to the position of the bands of the spectrum of laboratory CH4 ice is observed in the bands at larger wavelengths (e.g. around 0.89 microns), but not at shorter wavelengths (the band around 0.73 microns is not shifted) this may be evidence for a vertical compositional gradient. Purer methane could have condensed first while 2003 UB313 moved towards aphelion during the last 200 years, and as the atmosphere gradually collapsed, the composition became more nitrogen-rich as the last, most volatile components condensed, and CH4 diluted in N2 is present in the outer surface layers.
description: Accepted in A&A
The role of mediation in the Russian and Ukraine conflict
Creators: name: Mohamud, Hussein Sabrie Abdi
Publisher: name: Zenodo
Year: 2025
Subjects: The role of mediation
in the Russian and
Ukraine conflict

description: ABSTRACT

This thesis delves into the nuanced and complex dynamics of the ongoing conflict between Russia and Ukraine, with a specific focus on the role of mediation in mitigating tensions and fosteringresolution. Through an in-depth analysis of historical context, diplomatic exchanges, and geopolitical considerations, the study seeks to understand the impact of mediation efforts on the trajectory of the conflict.

Utilizing a qualitative research approach, the thesis examines various mediation strategies employed by international actors and regional entities. It explores the effectiveness of these interventions inde-escalating hostilities, promoting dialogue, and laying the groundwork for sustainable peace.

The findings shed light on the challenges and opportunities associated with mediation in the Russia-Ukraine conflict, offering valuable insights for policymakers, practitioners, and scholars interestedin conflict resolution and international relations. The study contributes to the broader discourse onthe role of mediation in complex geopolitical disputes and provides recommendations for future diplomatic initiatives in the context of this enduring conflict.
Extended geometries
Creators: name: Cederwall, Martin
name: Palmkvist, Jakob
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present a unified and completely general formulation of extended geometry, characterised by a Kac-Moody algebra and a highest weight coordinate module. Generalised diffeomorphisms are constructed, as well as solutions to the section constraint. Generically, additional ("ancillary") gauge transformations are present, and we give a concrete criterion determining when they appear. A universal form of the (pseudo-)action determines the dynamics in all cases without ancillary transformations, and also for a restricted set of cases based on the adjoint representation of a finite-dimensional simple Lie group. Our construction reproduces (the internal sector of) all previously considered cases of double and exceptional field theories.
description: 29 pp. v2: reference added, conclusion section expanded, minor other changes. v3: small changes
Pathway-specific trafficking of native AMPARs by in vivo experience.
Creators: name: Clem, Roger L.
name: Barth, Alison L.
Publisher: name: Carnegie Mellon University
Year: 2006
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: An accumulating body of evidence supports the notion that trafficking of AMPA receptors (AMPARs) underlies strengthening of glutamatergic synapses and, in turn, learning and memory in the behaving animal. However, without exception, these experiments have been performed using artificial stimulation protocols, cultured neurons, or viral-overexpression systems that can significantly alter the normal function of AMPARs. Using a single-whisker experience protocol that significantly enhances neuronal responses in vivo, we have targeted neurons in and around the spared whisker column of fosGFP transgenic mice for whole-cell recording. Here we show that in vivo experience induces the pathway-specific strengthening of neocortical excitatory synapses. By assaying AMPARs for rectification and sensitivity to joro spider toxin, we find that in vivo experience induces the delivery of native GluR2-lacking receptors at spared, but not deprived, inputs. These data demonstrate that pathway-specific trafficking of GluR2-lacking AMPARs is a normal feature of synaptic strengthening that underlies experience-dependent plasticity in the behaving animal.
title: ADCO, Cartulaire de Cîteaux pour les possessions de Beaune et du Beaunois (XVe siècle), Cart. 174 (11 H 79), 56 pages, f. 0005
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: CBMA
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour les possessions de Beaune et du Beaunois (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 174 (11 H 79), 56 pages, f. 0005, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Beaune et du Beaunois (XVe siècle), Archives départementales de la Côte-d'Or, Cart. 174 (11 H 79), 56 pages, f. 0005, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Realisation of chiral symmetry in the domain model of QCD
Creators: name: Kalloniatis, A. C.
name: Nedelko, S. N.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The domain model for the QCD vacuum has previously been developed and shown to exhibit confinement of quarks and strong correlation of the local chirality of quark modes and duality of the background domain-like gluon field. Quark fluctuations satisfy a chirality violating boundary conditions parametrized by a random chiral angle $α_j$ on the $j-th$ domain. The free energy of an ensemble of $N\to\infty$ domains depends on $\{α_j, j=1... N\}$ through the logarithm of the quark determinant. Its parity odd part is given by the axial anomaly. The anomaly contribution to the free energy suppresses continuous axial U(1) degeneracy in the ground state, leaving only a residual axial Z(2) symmetry. This discrete symmetry and flavour $SU(N_f)_L\times SU(N_f)_R$ chiral symmetry in turn are spontaneously broken with a quark condensate arising due to the asymmetry of the spectrum of Dirac operator. In order to illustrate the splitting between the $η'$ from octet pseudoscalar mesons realised in the domain model, we estimate the masses of light pseudoscalar and vector mesons.
description: 27 pages, uses RevTeX, 3 figures. v.2. includes additional references and comments
A RELIGIOSIDADE FRENTE AO LUTO DE FAMILIARES CUIDADORES DE PACIENTES ONCOLÓGICOS: UM RELATO DE EXPERIÊNCIA
Creators: name: MORAES, Ana Carolina de Sousa Gomes
Publisher: name: Zenodo
Year: 2024
Subjects: Luto
Familiares Cuidadores
Cuidados Paliativos.
Espiritualidade

description: O diagnóstico de uma doença grave como câncer traz uma série de implicações na vida de quem descobre a doença e de seus familiares. Nesse momento, há diversas vivências de processos de lutos, como o luto pessoal, o luto que surgem com as alterações na dinâmica familiar, o luto social, o espiritual/religioso que surge com a finitude e, por fim, o luto pela morte propriamente dita
Linum maritimum Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Malpighiales
Linaceae
Linum
Linum maritimum

description: Linum maritimum Linnaeus, Species Plantarum 1: 280. 1753.
"Habitat in Austria ad Thermas badensis, Monspelii." RCN: 2211.
Type not designated.
 Original material: Herb. Linn. No. 396.20 (LINN); Herb. Burser XII: 39 (UPS); Herb. Clifford: 114, Linum 3 (BM); [icon] in Bauhin & Cherler, Hist. Pl. Univ. 3(2): 454. 1651; [icon] in Dodoëns, Stirp. Hist. Pempt., ed. 2: 534. 1616.
 Current name: Linum maritimum L. (Linaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 634, DOI: 10.5281/zenodo.291971
Unoriented topological quantum field theory and link homology
Creators: name: Turaev, Vladimir
name: Turner, Paul
Publisher: name: arXiv
Year: 2005
Subjects: subject: Geometric Topology (math.GT)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 57M25, 57R56, 81T40

description: We investigate link homology theories for stable equivalence classes of link diagrams on orientable surfaces. We apply (1+1)-dimensional unoriented topological quantum field theories to Bar-Natan's geometric formalism to define new theories for stable equivalence classes.
description: This is the version published by Algebraic & Geometric Topology on 24 August 2006
Pathway of ATP utilization and duplex rRNA unwinding by the DEAD-box helicase, DbpA.
Creators: name: Henn, Arnon
name: Wenxiang  Cao
name: Licciardello, Nicholas
name: Heitkamp, Sara E.
name: Hackney, David
name: Cruz, Enrique M. De La
Publisher: name: Carnegie Mellon University
Year: 2010
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: DEAD-box RNA helicase proteins use the energy of ATP hydrolysis to drive the unwinding of duplex RNA. However, the mechanism that couples ATP utilization to duplex RNA unwinding is unknown. We measured ATP utilization and duplex RNA unwinding by DbpA, a non-processive bacterial DEAD-box RNA helicase specifically activated by the peptidyl transferase center (PTC) of 23S rRNA. Consumption of a single ATP molecule is sufficient to unwind and displace an 8 base pair rRNA strand annealed to a 32 base pair PTC-RNA "mother strand" fragment. Strand displacement occurs after ATP binding and hydrolysis but before P(i) product release. P(i) release weakens binding to rRNA, thereby facilitating the release of the unwound rRNA mother strand and the recycling of DbpA for additional rounds of unwinding. This work explains how ATPase activity of DEAD-box helicases is linked to RNA unwinding.
Enhancement and suppression of heat transfer by MHD turbulence
Creators: name: Lazarian, A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study of the effect of turbulence on heat transfer within magnetized plasmas for energy injection velocities both larger and smaller that the Alfven speed. We find that in the latter regime the heat transfer is partially suppressed, while in the former regime the effects of turbulence depend on the intensity of driving. In fact, the scale l at which the turbulent velocity is equal the Alfven velocity is a new important parameter. When the electron mean free path is larger than l, the stronger the the turbulence, the lower thermal conductivity by electrons is. The turbulent motions, however, induces their own advective heat transport, which, for the parameters of intracluster medium (ICM) provides effective heat diffusivity that exceeds the classical Spitzer value.
description: 4 pages, misprint corrected, published ApJL version is correct