cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Structural consequences of cyclophilin A binding on maturational refolding in human immunodeficiency virus type 1 capsid
Creators: name: Dietrich, Lars
name: Ehrlich, Lorna S.
name: LaGrassa, Tracy J.
name: Ebbets-Reed, Dana
name: Carter, Carol
Publisher: name: Columbia University
Year: 2001
Subjects: Virology
Medicine

description: While several cellular proteins are incorporated in the human immunodeficiency virus type 1 virion, cyclophilin (CyP) A is the only one whose absence has been demonstrated to impair infectivity. Incorporation of the cytosolic protein results from interaction with a highly exposed Pro-rich loop in the N-terminal region of the capsid (CA) domain of the precursor polyprotein, Pr55(Gag). Even when prevented from interacting with CyP A, Pr55Gag still forms particles that proceed to mature into morphologically wild-type virions, suggesting that CyP A influences a postassembly event. The nature of this CyP A influence has yet to be elucidated. Here, we show that while CyP A binds both Gag and mature CA proteins, the two binding interactions are actually different. Tryptophan 121 (W121) in CyP A distinguished the two proteins: a phenylalanine substitution (W121F) impaired binding of mature CA protein but not of Gag. This indicates the occurrence of a maturation-dependent switch in the conformation of the Pro-rich loop. A structural consequence of Gag binding to CyP A was to block this maturational refolding, resulting in a 24-kDa CA protein retaining the immature Pro-rich loop conformation. Using trypsin as a structure probe, we demonstrate that the conformation of the C-terminal region in mature CA is also a product of maturational refolding. Binding to wild-type CyP A altered this conformation, as indicated by a reduction in the accessibility of Cys residue(s) in the region to chemical modification. Hence, the end result of binding to CyP A, whether the Pro-rich loop is in the context of Gag or mature CA protein, is a structurally modified mature CA protein. The postassembly role of CyP A may be mediated through these modified mature CA proteins.
ТЕОРЕТИЧЕСКАЯ МОДЕЛЬ ПЕРЕНОСА ЧАСТИЦ В РАЗВЕТВЛЕННОМ КРОВЕНОСНОМ СОСУДЕ В ПРИСУТСТВИИ МАГНИТНОГО ПОЛЯ
Creators: name: С.Ф.Салем
name: В.В.Тучин
Publisher: name: Методы компьютерной диагностики в биологии и медицине – 2020
Year: 2020
Subjects: разветвляющиеся сосуды
математическое моделирование
магнитные наночастицы
магнетизм
ньютоновская жидкость
кровеносный сосуд
постоянный магнит
компьютерное моделирование

description: В работе численно исследованы механизмы движения магнитных наночастиц в крови в постоянном магнитном поле. Уравнения движения частиц в потоке были решены численно с помощью программного обеспечения COMSOL Multiphysics®.
Transverse spin Seebeck vs. Anomalous and Planar Nernst Effects in Permalloy Thin Films
Creators: name: Schmid, M.
name: Srichandan, S.
name: Meier, D.
name: Kuschel, T.
name: Schmalhorst, J. -M.
name: Vogel, M.
name: Reiss, G.
name: Strunk, C.
name: Back, C. H.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Transverse magneto-thermoelectric effects are studied in permalloy thin films grown on MgO and GaAs substrates and compared to those grown on suspended SiN membranes. The transverse voltage along platinum strips patterned on top of the permalloy films is measured vs. the external magnetic field as a function of angle and temperature gradient. After the identification of the contribution of the planar and anomalous Nernst effects, we find an upper limit for the transverse spin Seebeck effect, which is several orders of magnitude smaller than previously reported.
ТЕОРЕТИЧЕСКОЕ ИЗУЧЕНИЕ ВЗАИМОДЕЙСТВИЯ ПОЛИАНИЛИНА И ПЕРОКСИДАЗЫ ХРЕНА
Creators: name: Е.С. Федотова
name: Н.А. Бурмистрова
Publisher: name: Методы компьютерной диагностики в биологии и медицине – 2020
Year: 2020
Subjects: полианилин
эмеральдин
пероксидаза хрена
RHF 6-31G(d
p)
молекулярная механика.

description: В работе проведено теоретическое изучение взаимодействия полианилина и пероксидазы хрена. Квантовохимический расчет участка цепи полианилина проводили методом Хартри-Фока (RHF 6-31G(d,p). Проведено сравнение геометрических и электронных характеристик олигомеров полианилина. Комплексы молекулы пероксидазы хрена с различным числом фрагментов полианилина изучены методом молекулярной механики (BIO+CHARMM). Показана возможность взаимодействия олигомеров полианилина с различными частями белковой молекулы.
Corner contribution to cluster numbers in the Potts model
Creators: name: Kovács, István A.
name: Elçi, Eren Metin
name: Weigel, Martin
name: Iglói, Ferenc
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: For the two-dimensional Q-state Potts model at criticality, we consider Fortuin-Kasteleyn and spin clusters and study the average number N_Gamma of clusters that intersect a given contour Gamma. To leading order, N_Gamma is proportional to the length of the curve. Additionally, however, there occur logarithmic contributions related to the corners of Gamma. These are found to be universal and their size can be calculated employing techniques from conformal field theory. For the Fortuin-Kasteleyn clusters relevant to the thermal phase transition we find agreement with these predictions from large-scale numerical simulations. For the spin clusters, on the other hand, the cluster numbers are not found to be consistent with the values obtained by analytic continuation, as conventionally assumed.
description: 9 pages, 6 figures
Sonnenfleckenzeichnung Nr. 28135.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.03.1990, erstellt von Hans Ulrich Keller.
Zusätzlich ist vermerkt: Sonnenturm
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der ehem. Eidgenössischen Sternwarte Zürich. Instrument: Coelostat/Teleskop: Das Sonnenlicht wurde über einen Coelostat in eine Vertikalachse, anschliessend von einem Umlenkungsspiegel durch ein Horizontalteleskop gelenkt, und von dessen Okular auf das vertikal fixierte "Sonnenblatt" projiziert.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit den statistischen Angaben, für die Werte g, f und mit einer Spalte für A: von blossem Auge sichtbare Flecken, beobachtet mit Hilfe eines korrekt-reduzierenden optischen Filters (naked eye sunspots).
Beobachtungstätigkeit am erwähnten Ort im Auftrag des Schweizerischen Militärdepartements, Bundesamt für Übermittlungstruppen (BAUEM): Zählungen am Fraunhoferschen Normalrefraktor und Zeichnungen am Zeiss-Coudé-Refraktor
Robust discovery of periodically expressed genes using the laplace periodogram
Creators: name: Liang, Kuo-Ching
name: Wang, Xiaodong
name: Li, Ta-Hsin
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Time-course gene expression analysis has become important in recent developments due to the increasingly available experimental data. The detection of genes that are periodically expressed is an important step which allows us to study the regulatory mechanisms associated with the cell cycle. In this work, we present the Laplace periodogram which employs the least absolute deviation criterion to provide a more robust detection of periodic gene expression in the presence of outliers. The Laplace periodogram is shown to perform comparably to existing methods for the Sacharomyces cerevisiae and Arabidopsis time-course datasets, and to outperform existing methods when outliers are present. Time-course gene expression data are often noisy due to the limitations of current technology, and may include outliers. These artifacts corrupt the available data and make the detection of periodicity difficult in many cases. The Laplace periodogram is shown to perform well for both data with and without the presence of outliers, and also for data that are non-uniformly sampled.
Sonnenfleckenzeichnung Nr. 28154.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.05.1990, erstellt von Hans Ulrich Keller.
Zusätzlich ist vermerkt: Sonnenturm
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der ehem. Eidgenössischen Sternwarte Zürich. Instrument: Coelostat/Teleskop: Das Sonnenlicht wurde über einen Coelostat in eine Vertikalachse, anschliessend von einem Umlenkungsspiegel durch ein Horizontalteleskop gelenkt, und von dessen Okular auf das vertikal fixierte "Sonnenblatt" projiziert.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit den statistischen Angaben, für die Werte g, f und mit einer Spalte für A: von blossem Auge sichtbare Flecken, beobachtet mit Hilfe eines korrekt-reduzierenden optischen Filters (naked eye sunspots).
Beobachtungstätigkeit am erwähnten Ort im Auftrag des Schweizerischen Militärdepartements, Bundesamt für Übermittlungstruppen (BAUEM): Zählungen am Fraunhoferschen Normalrefraktor und Zeichnungen am Zeiss-Coudé-Refraktor
Sonnenfleckenzeichnung Nr. 28217.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.09.1990, erstellt von Hans Ulrich Keller.
Zusätzlich ist vermerkt: Sonnenturm
Creators: name: Eidgenössische Sternwarte in Zürich (ETH Zürich bzw. vor 1911 Polytechnikum)
Publisher: name: [s.n.]
Year: 1990

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der ehem. Eidgenössischen Sternwarte Zürich. Instrument: Coelostat/Teleskop: Das Sonnenlicht wurde über einen Coelostat in eine Vertikalachse, anschliessend von einem Umlenkungsspiegel durch ein Horizontalteleskop gelenkt, und von dessen Okular auf das vertikal fixierte "Sonnenblatt" projiziert.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit den statistischen Angaben, für die Werte g, f und mit einer Spalte für A: von blossem Auge sichtbare Flecken, beobachtet mit Hilfe eines korrekt-reduzierenden optischen Filters (naked eye sunspots).
Beobachtungstätigkeit am erwähnten Ort im Auftrag des Schweizerischen Militärdepartements, Bundesamt für Übermittlungstruppen (BAUEM): Zählungen am Fraunhoferschen Normalrefraktor und Zeichnungen am Zeiss-Coudé-Refraktor
$SL(2,R)\times U(1)$ symmetry and quasinormal modes in the self-dual warped AdS black hole
Creators: name: Chen, Yuan
name: Guo, Wei
name: Shi, Kai
name: Zhang, Hongbao
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The algebraic approach to the spectrum of quasinormal modes has been made as simple as possible for the BTZ black hole by the strategy developed in \cite{Zhang}. By working with the self-dual warped AdS black hole, we demonstrate in an explicit way that such a strategy can be well adapted to those warped AdS balck holes with the $SL(2,R)\times U(1)$ isometry. To this end, we first introduce two associated tensor fields with the quadratic Casimir of $SL(2,R)\times U(1)$ Lie algebra in the self-dual warped AdS black hole and show that they correspond essentially to the metric and volume element up to a constant prefactor, respectively. Then without appealing to any concrete coordinate system, we can further show that the solutions to the equations of motion for the scalar, vector, spinor fields all fall into the representations of the $SL(2,R)\times U(1)$ Lie algebra by a purely abstract tensor and spinor analysis. Accordingly, the corresponding spectrum of quasinormal modes for each fixed azimuthal quantum number can be derived algebraically as the infinite tower of descendants of the highest weight mode of the $SL(2,R)$ Lie subalgebra.
description: References updated, typos corrected, clarifications made, version to appear in JHEP
Metaphors and Marriage Plots: Jane Eyre, The Egoist, and Metaphoric Dialogue in the Victorian Novel
Creators: name: Gray, Erik I.
Publisher: name: Columbia University
Year: 2014
Subjects: British literature
Irish literature
Comparative literature

description: One of the most distinctive features of Victorian dialogue is the speakers’ tendency to take up and develop one another’s metaphors. This practice, which appears as frequently in actual recorded conversations as in fictional ones, is common in all sorts of situations, but it takes on a particular significance when the interlocutors are potential marriage partners. According to a widespread understanding, enshrined in the Book of Common Prayer, marriage itself is a metaphor. Literary theorists, meanwhile, particularly in the early nineteenth century, frequently describe metaphor as a type of marriage — a joining together of diverse but complementary concepts. Hence it is worth attending when an unmarried man and woman share in the creation of a single metaphor. Focusing on two representative Victorian novels, Charlotte Brontë’s Jane Eyre and George Meredith’s The Egoist, this essay suggests two major ways in which the trope is significant. First, it reflects an important shift in the conception of matrimony in England over the course of the Victorian period, from an ideal of marriage as total merging towards an increasing recognition of distinction-within-union. Second, the practice of sharing metaphor can serve in a novel, not just as a marker, but as a microcosm of conjugal compatibility; even in novels that end as soon as the lovers marry, these dialogues permit the reader to witness, in essence, a marital relationship.
Genome screen in familial intracranial aneurysm
Creators: name: Foroud, Tatiana
name: Sauerbeck, Laura
name: Brown, Robert
name: Anderson, Craig
name: Woo, Daniel
name: Kleindorfer, Dawn
name: Flaherty, Matthew
name: Deka, Ranjan
name: Hornung, Richard
name: Meissner, Irene
name: Bailey-Wilson, Joan
name: Langefeld, Carl
name: Rouleau, Guy
name: Connolly Jr., E. Sander
name: Lai, Dongbing
name: Koller, Daniel
name: Huston, John
name: Broderick, Joseph
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Individuals with 1st degree relatives harboring an intracranial aneurysm (IA) are at an increased risk of IA, suggesting genetic variation is an important risk factor. Methods: Families with multiple members having ruptured or unruptured IA were recruited and all available medical records and imaging data were reviewed to classify possible IA subjects as definite, probable or possible IA or not a case. A 6 K SNP genome screen was performed in 333 families, representing the largest linkage study of IA reported to date. A 'narrow' (n = 705 definite IA cases) and 'broad' (n = 866 definite or probable IA) disease definition were used in multipoint model-free linkage analysis and parametric linkage analysis, maximizing disease parameters. Ordered subset analysis (OSA) was used to detect gene × smoking interaction. Model-free linkage analyses detected modest evidence of possible linkage (all LOD < 1.5). Parametric analyses yielded an unadjusted LOD score of 2.6 on chromosome 4q (162 cM) and 3.1 on chromosome 12p (50 cM). Significant evidence for a gene × smoking interaction was detected using both disease models on chromosome 7p (60 cM; p ≤ 0.01). Our study provides modest evidence of possible linkage to several chromosomes. These data suggest it is unlikely that there is a single common variant with a strong effect in the majority of the IA families. Rather, it is likely that multiple genetic and environmental risk factors contribute to the susceptibility for intracranial aneurysms.
Light Ring behind Wormhole Throat: Geodesics, Images and Shadows
Creators: name: Huang, Hyat
name: Kunz, Jutta
name: Yang, Jinbo
name: Zhang, Cong
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The geodesics of the Ellis-Bronnikov wormhole with two parameters are studied. The asymmetric wormhole has only one light ring and one innermost stable circular orbit located on one side of the wormhole throat. Consequently, certain light rays can be reflected back by the wormhole. Additionally, the same wormhole can have different appearances on both sides of the throat. We present novel images of the wormhole with a light ring behind the throat in a scenario with an accretion disk as the light source and in a backlit wormhole scenario, which are distinct from the images of other compact objects and have the potential to be observed.
description: 26 pages, 14 figures, add references
Modernist Materials Synthesis: Finding Thermodynamic Shortcuts with Hyperdimensional Chemistry
Creators: name: Neilson, James R
name: McDermott, Matthew J
name: Persson, Kristin A
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Synthesis remains a challenge for advancing materials science. A key focus of this challenge is how to enable selective synthesis, particularly as it pertains to metastable materials. This perspective addresses the question: how can ``spectator'' elements, such as those found in double ion exchange (metathesis) reactions, enable selective materials synthesis? By observing reaction pathways as they happen (\emph{in situ}) and calculating their energetics using modern computational thermodynamics, we observe transient, crystalline intermediates that suggest that many reactions attain a local thermodynamic equilibrium dictated by local chemical potentials far before achieving a global equilibrium set by the average composition. Using this knowledge, one can thermodynamically ``shortcut'' unfavorable intermediates by including additional elements beyond those of the desired target, providing access to a greater number of intermediates with advantageous energetics and selective phase nucleation. Ultimately, data-driven modeling that unites first-principles approaches with experimental insights will refine the accuracy of emerging predictive retrosynthetic models for complex materials synthesis.
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
Creators: name: Dharia, Neekesh
name: Sidhu, Amar
name: Cassera, María
name: Westenberger, Scott
name: Bopp, Selina
name: Eastman, Rich
name: Plouffe, David
name: Batalov, Serge
name: Park, Daniel
name: Volkman, Sarah
name: Wirth, Dyann
name: Zhou, Yingyao
name: Fidock, David Armand
name: Winzeler, Elizabeth
Publisher: name: Columbia University
Year: 2009
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Plasmodium falciparum

description: The identification of genetic changes that confer drug resistance or other phenotypic changes in pathogens can help optimize treatment strategies, support the development of new therapeutic agents, and provide information about the likely function of genes. Elucidating mechanisms of phenotypic drug resistance can also assist in identifying the mode of action of uncharacterized but potent antimalarial compounds identified in high-throughput chemical screening campaigns against Plasmodium falciparum. Here we show that tiling microarrays can detect de novo a large proportion of the genetic changes that differentiate one genome from another. We show that we detect most single nucleotide polymorphisms or small insertion deletion events and all known copy number variations that distinguish three laboratory isolates using readily accessible methods. We used the approach to discover mutations that occur during the selection process after transfection. We also elucidated a mechanism by which parasites acquire resistance to the antimalarial fosmidomycin, which targets the parasite isoprenoid synthesis pathway. Our microarray-based approach allowed us to attribute in vitro derived fosmidomycin resistance to a copy number variation event in the pfdxr gene, which enables the parasite to overcome fosmidomycin-mediated inhibition of isoprenoid biosynthesis. We show that newly emerged single nucleotide polymorphisms can readily be detected and that malaria parasites can rapidly acquire gene amplifications in response to in vitro drug pressure. The ability to define comprehensively genetic variability in P. falciparum with a single overnight hybridization creates new opportunities to study parasite evolution and improve the treatment and control of malaria.
Reconsidering the “Idea” of Evidence in Evidence-based Policy and Practice
Creators: name: Mullen, Edward Joseph
Publisher: name: Columbia University
Year: 2015
Subjects: Evidence
Social work administration
Evidence-based social work
Social service

description: Evidence-based policy and practice (EBP) has become an important social work conceptual framework. Yet, the core EBP concept, the concept of evidence, remains ill-defined. I propose a modification of the concept of evidence as applied to EBP effectiveness questions. As a basis for this reformulation ideas about evidence are examined from cross-disciplinary and multidisciplinary perspectives including epistemology, philosophy of science, evidence-science, and law. I propose that for EBP effectiveness questions: (1) to be considered “relevant evidence” an explanatory connection between an intervention and an outcome must be established rather than a mere association; (2) the EBP definition of “best available evidence” should include total available evidence (rather than a subset) about effectiveness, causal roles (i.e. mechanisms), and support factors and be inclusive of high quality experimental and observational studies as well as high-quality mechanistic reasoning; (3) the familiar five-step EBP process should be expanded to include formulation of warranted, evidence-based arguments and that evidence appraisal be guided by three high level criteria of relevance, credibility, and strength rather than rigid evidence hierarchies; (4) comparative effectiveness research strategies, especially pragmatic controlled studies, hold promise for providing relevant and actionable evidence needed for policy and practice decision-making and successful implementation.
Todesanzeige von Lambert Heinrich Röhl an [Johann III] Bernoulli
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1790
Subjects: Röhl, Lambert Heinrich1724-1790Lambert HeinrichRoehl

description: Bl. 31: Briefumschlag mit handschriftlicher Adresse und schwarzem Siegel
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire März 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
The condensation of ideal Bose gas in a gravitational field in the framework of Dunkl-statistic
Creators: name: Hamil, B.
name: Lütfüoğlu, B. C.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In the framework of the theory of Dunkl-deformed bosons, Bose-Einstein condensation of two and three-dimensional Dunkl-boson gases confined in the one-dimensional gravitational field is investigated. Using the semi-classical approximation method, we calculate the expressions of the Dunkl-critical temperature $T_{c}^{D}$, the ground state population $\frac{N_{0}^{D}}{N}$ and the Dunkl-mean energy and Dunkl-specific heat functions. Further numerical calculation shows that the condensation temperature ratio $\frac{T_{c}^{D}}{T_{c}^{B}}$ increases with the increasing Wigner parameter.
description: 10 pages 4 figures
The model of a level crossing with a Coulomb band: exact probabilities of nonadiabatic transitions
Creators: name: Lin, J
name: Sinitsyn, N A
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We derive an exact solution of an explicitly time-dependent multichannel model of quantum mechanical nonadiabatic transitions. Our model corresponds to the case of a single linear diabatic energy level interacting with a band of an arbitrary N states, for which the diabatic energies decay with time according to the Coulomb law. We show that the time-dependent Schroedingier equation for this system can be solved in terms of Meijer functions whose asymptotics at a large time can be compactly written in terms of elementary functions that depend on the roots of an Nth order characteristic polynomial. Our model can be considered a generalization of the Demkov-Osherov model. In comparison to the latter, our model allows one to explore the role of curvature of the band levels and diabatic avoided crossings.
description: 18 pages, 3 figures
The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population
Creators: name: Gern, James
name: Visness, Cynthia
name: Gergen, Peter
name: Wood, Robert
name: Bloomberg, Gordon
name: O'Connor, George
name: Kattan, Meyer
name: Sampson, Hugh
name: Witter, Frank
name: Sandel, Megan
name: Shreffler, Wayne
name: Wright, Rosalind
name: Arbes, Samuel
name: Busse, William
Publisher: name: Columbia University
Year: 2009
Subjects: Environmental health

description: The incidence and morbidity of wheezing illnesses and childhood asthma is especially high in poor urban areas. This paper describes the study design, methods, and population of the Urban Environment and Childhood Asthma (URECA) study, which was established to investigate the immunologic causes of asthma among inner-city children.
URECA is an observational prospective study that enrolled pregnant women in central urban areas of Baltimore, Boston, New York City, and St. Louis and is following their offspring from birth through age 7 years. The birth cohort consists of 560 inner-city children who have at least one parent with an allergic disease or asthma, and all families live in areas in which at least 20% of the population has incomes below the poverty line. In addition, 49 inner-city children with no parental history of allergies or asthma were enrolled. The primary hypothesis is that specific urban exposures in early life promote a unique pattern of immune development (impaired antiviral and increased Th2 responses) that increases the risk of recurrent wheezing and allergic sensitization in early childhood, and of asthma by age 7 years. To track immune development, cytokine responses of blood mononuclear cells stimulated ex vivo are measured at birth and then annually. Environmental assessments include allergen and endotoxin levels in house dust, pre- and postnatal maternal stress, and indoor air nicotine and nitrogen dioxide. Nasal mucous samples are collected from the children during respiratory illnesses and analyzed for respiratory viruses. The complex interactions between environmental exposures and immune development will be assessed with respect to recurrent wheeze at age 3 years and asthma at age 7 years.
The overall goal of the URECA study is to develop a better understanding of how specific urban exposures affect immune development to promote wheezing illnesses and asthma.
Comparison Theorems for Gibbs Measures
Creators: name: Rebeschini, Patrick
name: van Handel, Ramon
Publisher: name: arXiv
Year: 2013
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: The Dobrushin comparison theorem is a powerful tool to bound the difference between the marginals of high-dimensional probability distributions in terms of their local specifications. Originally introduced to prove uniqueness and decay of correlations of Gibbs measures, it has been widely used in statistical mechanics as well as in the analysis of algorithms on random fields and interacting Markov chains. However, the classical comparison theorem requires validity of the Dobrushin uniqueness criterion, essentially restricting its applicability in most models to a small subset of the natural parameter space. In this paper we develop generalized Dobrushin comparison theorems in terms of influences between blocks of sites, in the spirit of Dobrushin-Shlosman and Weitz, that substantially extend the range of applicability of the classical comparison theorem. Our proofs are based on the analysis of an associated family of Markov chains. We develop in detail an application of our main results to the analysis of sequential Monte Carlo algorithms for filtering in high dimension.
description: 55 pages
Diverse Molecular Structures Across The Whole Star-Forming Disk of M83: High fidelity Imaging at 40pc Resolution
Creators: name: Koda, Jin
name: Hirota, Akihiko
name: Egusa, Fumi
name: Sakamoto, Kazushi
name: Sawada, Tsuyoshi
name: Heyer, Mark
name: Baba, Junichi
name: Boissier, Samuel
name: Calzetti, Daniela
name: Meyer, Jennifer Donovan
name: Elmegreen, Bruce G.
name: de Paz, Armando Gil
name: Harada, Nanase
name: Ho, Luis C.
name: Kobayashi, Masato I. N.
name: Kuno, Nario
name: Lee, Amanda M
name: Madore, Barry F.
name: Maeda, Fumiya
name: Martin, Sergio
name: Muraoka, Kazuyuki
name: Nakanishi, Kouichiro
name: Onodera, Sachiko
name: Pineda, Jorge L.
name: Scoville, Nick
name: Watanabe, Yoshimasa
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present high-fidelity CO(1-0) imaging of molecular gas across the full star-forming disk of M83, using ALMA's 12m, 7m, and TP arrays and the MIRIAD package. The data have a mass sensitivity and resolution of 10^4Msun and 40 pc. The full disk coverage shows that the characteristics of molecular gas change radially from the center to outer disk. The molecular gas distribution shows coherent large-scale structures in the inner part, including the central concentration, bar offset ridges, and prominent molecular spiral arms. In the outer disk, the spiral arms appear less spatially coherent, and even flocculent. Massive filamentary gas concentrations are abundant even in the interarm regions. Building up these structures in the interarm regions would require a very long time (~>100Myr). Instead, they must have formed within stellar spiral arms and been released into the interarm regions. For such structures to survive through the dynamical processes, the lifetimes of these structures and their constituent molecules and molecular clouds must be long (~>100Myr). These interarm structures host little or no star formation traced by Halpha. The new map also shows extended CO emission, which likely represents an ensemble of unresolved molecular clouds.
description: Accepted for publication in ApJ
Subskriptionsanzeige für neue Auflage des Dictionnaire Encyclopédique
Creators: name: Panckoucke, Charles Joseph
Publisher: name: [s.n.]
Year: 1771

description: von [Charles Joseph Panckoucke]
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis
Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events
Creators: name: Mani, Venkatesh
name: Muntner, Paul
name: Gidding, Samuel
name: Aguiar, Silvia
name: El Aidi, Hamza
name: Weinshelbaum, Karen
name: Taniguchi, Hiroaki
name: Van Der Geest, Rob
name: Reiber, Johan
name: Bansilal, Sameer
name: Farkouh, Michael
name: Fuster, Valentin
name: Postley Jr., John Edward
name: Woodward, Mark
name: Fayad, Zahi
Publisher: name: Columbia University
Year: 2009
Subjects: Medicine

description: Patients with prior major cardiovascular or cerebrovascular events (MACE) are more likely to have future recurrent events independent of traditional cardiovascular disease risk factors. The purpose of this study was to determine if patients with traditional risk factors and prior MACE had increased cardiovascular magnetic resonance (CMR) plaque burden measures compared to patients with risk factors but no prior events. Black blood carotid and thoracic aorta images were obtained from 195 patients using a rapid extended coverage turbo spin echo sequence. CMR measures of plaque burden were obtained by tracing lumen and outer vessel wall contours. Patients with prior MACE had significantly higher MR plaque burden (wall thickness, wall area and normalized wall index) in carotids and thoracic aorta compared to those without prior MACE (Wall thickness carotids: 1.03 ± 0.03 vs. 0.93± 0.03, p = 0.001; SD wall thickness carotids: 0.137 ± 0.0008 vs. 0.102 ± 0.0004, p < 0.001; wall thickness aorta: 1.63 ± 0.10 vs. 1.50 ± 0.04, p = 0.009; SD wall thickness aorta: 0.186 ± 0.035 vs. 0.139 ± 0.012, p = 0.009 respectively). Plaque burden (wall thickness) and plaque eccentricity (standard deviation of wall thickness) of carotid arteries were associated with prior MACE after adjustment for age, sex, and traditional risk factors. Area under ROC curve (AUC) for discriminating prior MACE improved by adding plaque eccentricity to models incorporating age, sex, and traditional CVD risk factors as model inputs (AUC = 0.79, p = 0.05). Conclusion: A greater plaque burden and plaque eccentricity is prevalent among patients with prior MACE.
ТЕРМОГРАФИЧЕСКАЯ ОЦЕНКА КОРРЕЛЯЦИИ ГЕМОДИНАМИКИ В КОНТРАЛАТЕРАЛЬНЫХ КОНЕЧНОСТЯХ
Creators: name: И.С. Залетов
name: Д.И. Майсков
name: А.В. Фомин
name: А.В. Скрипаль
name: А.А. Сагайдачный
Publisher: name: Методы компьютерной диагностики в биологии и медицине – 2020
Year: 2020
Subjects: термография
система кровообращения
гемодинамика
окклюзионная проба.

description: Рассматривается возможность использования метода термографической оценки корреляции гемодинамики в контралатеральных конечностях с целью диагностики нарушения процессов регуляции кровообращения. Производится оценка коэффициентов корреляции температурных кривых и их вейвлет–спектров в низкочастотном диапазоне колебаний менее 0.02 Гц.
Lasing and high temperature phase transitions in atomic systems with dressed state polaritons
Creators: name: Chestnov, I. Yu.
name: Alodjants, A. P.
name: Arakelian, S. M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We consider the fundamental problem of high temperature phase transitions in the system of high density two-level atoms off-resonantly interacting with a pump field in the presence of optical collisions (OCs) and placed in the cavity. OCs are considered in the framework of thermalization of atomic dressed state (DS) population. For the case of a strong atom-field coupling condition we analyze the problem of thermodynamically equilibrium superradiant phase transition for the order parameter representing a real amplitude of cavity mode and taking place as a result of atomic DSs thermalization process. Such transition is also connected with condensed (coherent) properties of low branch (LB) DS-polaritons occurring in the cavity. For describing non-equilibrium phase transitions we derive Maxwell-Bloch like equations which account for cavity decay rate, collisional decay rate and spontaneous emission. Various aspects of transitions to laser field formation by using atomic DS levels for both positive and negative detuning of a pump field from atomic transition frequency are studied in detail. It is revealed, that for positive atom-light detuning DS lasing can be obtained in the presence of quasi-equilibrium DS population that corresponds to a true two-level atomic system with the inversion in nonresonant limit.
description: 12 pages, 8 figures
Vědci a knihovny na cestě k open science
Creators: name: Roubík, Hynek
Publisher: name: Zenodo
Year: 2023
Subjects: BA2023
open science

description: Prezentováno na konferenci Bibliotheca academica 2023.
description: Jak se mění vědecký výzkum a jakou podporu mohou knihovny poskytovat? Vzhledem k aktuálním trendům v oblasti open science dochází k významným změnám ve vědeckém výzkumu. Vědečtí pracovníci se setkávají s novými výzvami a potřebami, které vyžadují odpovídající podporu ze strany knihoven. Jaké jsou změny ve vědeckém výzkumu a jak se to promítá do potřeb vědeckých pracovníků? Jaké služby a zdroje mohou knihovny poskytovat, aby vědcům usnadnily jejich práci v kontextu otevřeného výzkumu? Společně se podíváme na to, jakým způsobem knihovny mohou efektivně reagovat na tyto nové požadavky a přispívat k úspěchu vědeckých pracovníků. Pojďme se zamyslet na tím, jak knihovny mohou aktivně spolupracovat s vědeckými pracovníky a nabídnout jim konkrétní řešení a podporu.
Anzeige betreffend Erscheinen der Encyclopaedie : adressiert an [Johann] III Bernoulli
Creators: name: Panckoucke, Charles Joseph
Publisher: name: [s.n.]
Year: 1776

description: von C[harles] [Joseph] Panckoucke
description: Enthält handschriftliche Anmerkungen und Adresse
description: Mit Oblate
description: Öffentliche Bibliothek der Universität Basel
description: Französisch
description: Verzeichnung=Description=Inventaire April 2016 HAN-Katalogisierungsregeln Vollständige Rekatalogisierung nach Standortverzeichnis und Briefkatalog
ТЕХНОЛОГИЧЕСКИЕ ФАКТОРЫ, ВЛИЯЮЩИЕ НА РЕЗУЛЬТАТИВНОСТЬ АДСОРБЦИИ ПОЛИЭЛЕКТРОЛИТОВ ИЗ РАСТВОРА
Creators: name: А.А. Масленникова
name: А.В. Козловский
name: С.В. Стецюра
Publisher: name: Методы компьютерной диагностики в биологии и медицине – 2020
Year: 2020
Subjects: фотостимулированная адсорбция
ионная сила раствора
полупроводник
фермент
полиэлектролит

description: На этапе формирования буферного слоя полиэтиленимина и чувствительного слоя глюкозооксидазы биосенсорной структуры с полупроводниковым преобразователем сигнала исследовано влияние освещения полупроводниковой подложки оптическим излучением (физический фактор) и варьирования ионной силы растворов полиэлектролитов (химический фактор) на морфологию формирующихся органических нанослоев. Выводы сделаны на основе статистического анализа изображений атомно-силовой микроскопии.
title: Oberst Walo N. GERBER 1881-1949
title: Gedenkfeier anlässlich der Bestattung von Oberst Walo N. Gerber, Freitag, den 29. April 1949 in der Kirche Enge in Zürich
titleType: Subtitle
Creators: name: Sonderegger, Hugo
name: Dietschi, Eugen
name: Haccius, E.
Publisher: name: Steno
Year: 1949
Subjects: subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Gerber, Walo Niklaus
subject: Reformierte Kirche Enge (Zürich)
subject: New York, NY
subject: Zürich

description: Inhalt: Ansprache von Herrn Nationalrat Dr. E. Dietschi, Basel ; Ansprache von Herrn Oberst E. Haccius, BERN ; Abdankungspredigt von Pfarrer Dr. theol. Hugo Sonderegger, Zollikon ; In Memoriam Walo N. Gerber : Gedächtnisrede am Trauerlunch des Rotary-Clubs Zürich
ЧИСЛЕННОЕ МОДЕЛИРОВАНИЕ ПОВЕДЕНИЯ СКЕЛЕТНОЙ МЫШЦЫ ПРИ РАЗЛИЧНЫХ ВИДАХ ВНЕШНИХ НАГРУЗОК
Creators: name: М.А. Петрова
name: И.Ю. Демин
Publisher: name: Методы компьютерной диагностики в биологии и медицине – 2020
Year: 2020
Subjects: численное моделирование
скелетная мышца
внешние воздействия

description: Приведены результаты численного моделирования поведения скелетной мышцы при различных видах внешних нагрузок: ударном и импульсном. Рассмотрена модель Дещеревского, моделирование проведено на примере изолированной портняжной мышцы лягушки.
The year-scale X-ray variations in the core of M87
Creators: name: Cheng, Yu-Lin
name: Xiang, Fei
name: Yu, Heng
name: Jia, Shu-Mei
name: Li, Xiang-Hua
name: Li, Cheng-Kui
name: Chen, Yong
name: Feng, Wen-Cheng
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The analysis of light variation of M87 can help us understand the disc evolution. In the past decade, M87 has experienced several short-term light variabilities related to flares. We also find there are year-scale X-ray variations in the core of M87. Their light variability properties are similar to clumpy-ADAF. By re-analyzing 56 $\it Chandra$ observations from 2007 to 2019, we distinguish the `non-flaring state' from `flaring state' in the light variability. After removing flaring state data, we identify 4 gas clumps in the nucleus and all of them can be well fitted by the clumpy-ADAF model. The average mass accretion rate is $\sim 0.16 \rm M_{\odot} yr^{-1}$. We analyze the photon index($Γ$)-flux(2-10keV) correlation between the non-flaring state and flaring state. For the non-flaring states, the flux is inversely proportional to the photon index. For the flaring states, we find no obvious correlation between the two parameters. In addition, we find that the flare always occurs at a high mass accretion rate, and after the luminosity of the flare reaches the peak, it will be accompanied by a sudden decrease in luminosity. Our results can be explained as that the energy released by magnetic reconnection destroys the structure of the accretion disc, thus the luminosity decreases rapidly and returns to normal levels thereafter.
Chemia in nuce, oder:, Kurze doch aufrichtige Anweisung zu der Wissenschaft der Zerlegung der Körper
Creators: name: Czapski, Paul T. von
Publisher: name: [s.n.]
Year: 1777

description: [P. T. C.]
description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Juli 2014
Supplementary File 2_Report_25 Nov 2022.docx
Creators: name: Dorsemans, Anne-Claire
name: Essop, Faadiel
name: Bourdon, Emmanuel
Publisher: name: figshare
Year: 2022
Subjects: Teacher and student wellbeing

description: Practical report Laboratory: Glycemic response to food intake
(N+1)-dimensional Lorentzian evolving wormholes supported by polytropic matter
Creators: name: Cataldo, Mauricio
name: Bahamonde, Sebastian
name: Arostica, Fernanda
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we study $(N+1)$-dimensional evolving wormholes supported by energy satisfying a polytropic equation of state. The considered evolving wormhole models are described by a constant redshift function and generalizes the standard flat Friedmann-Robertson-Walker spacetime. The polytropic equation of state allows us to consider in $(3+1)$-dimensions generalizations of the phantom energy and the generalized Chaplygin gas sources.
description: 6 pages, 2 figures, accepted for publication in European Physical Journal C
Probing genetic overlap among complex human phenotypes
Creators: name: Rzhetsky, Andrey
name: Wajngurt, David
name: Park, Naeun
name: Zheng, Tian
Publisher: name: Columbia University
Year: 2006
Subjects: subject: Biometry
subject: Genetics
subject: FOS: Biological sciences

description: Geneticists and epidemiologists often observe that certain hereditary disorders cooccur in individual patients significantly more (or significantly less) frequently than expected, suggesting there is a genetic variation that predisposes its bearer to multiple disorders, or that protects against some disorders while predisposing to others. We suggest that, by using a large number of phenotypic observations about multiple disorders and an appropriate statistical model, we can infer genetic overlaps between phenotypes. Our proof-of-concept analysis of 1.5 million patient records and 161 disorders indicates that disease phenotypes form a highly connected network of strong pairwise correlations. Our modeling approach, under appropriate assumptions, allows us to estimate from these correlations the size of putative genetic overlaps. For example, we suggest that autism, bipolar disorder, and schizophrenia share significant genetic overlaps. Our disease network hypothesis can be immediately exploited in the design of genetic mapping approaches that involve joint linkage or association analyses of multiple seemingly disparate phenotypes.
First-principles study on the superconductivity of N-doped fcc-LuH3
Creators: name: Huo, Zihao
name: Duan, Defang
name: Ma, Tiancheng
name: Jiang, Qiwen
name: Zhang, Zihan
name: An, Decheng
name: Tian, Fubo
name: Cui, Tian
Publisher: name: arXiv
Year: 2023
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Recently, room-temperature superconductor has been claimed in a nitrogen-doped lutetium hydride at near-ambient pressure [Nature 615, 244 (2023)]. Using X-ray diffraction (XRD) and Raman spectra analysis, the authors believed that the superconducting properties can most probably be attributed to Fm-3m-LuH3δNε. Here, we systematic study the phase diagram of Lu-N-H at 1 GPa by using first-principle theory and find that there have no thermodynamically stable ternary compounds. Besides, we analyzed the dynamically stability and superconducting properties of N-doped Fm-3m-LuH3 using virtual crystal approximation (VCA) and supercell method. Our theoretical results show that the Tc of N-doped LuH3 cannot reach the level of room-temperature.
MODERN TENDENCIES OF SCHOOL EDUCATION AND THE NEW STAGE OF REFORMS IN THE REGION OF NAVOI
Creators: name: Shirinova, Firuza
Publisher: name: Zenodo
Year: 2023

description: This article discusses the state policy on the issue of youth education, reforms in the activity of pre-school educational organizations, which are the first link of education, their results, and the work being carried out in Navoi region. Also, issues of implementation of the tasks specified in the "Bolajon" State Program in Navoi region were revealed.
Convergent Evolution of Hyperswarming Leads to Impaired Biofilm Formation in Pathogenic Bacteria
Creators: name: Sakhtah, Hassan
name: Dietrich, Lars
Publisher: name: Columbia University
Year: 2013
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry
subject: Genetics
subject: Evolution (Biology)

description: Most bacteria in nature live in surface-associated communities rather than planktonic populations. Nonetheless, how surface-associated environments shape bacterial evolutionary adaptation remains poorly understood. Here, we show that subjecting Pseudomonas aeruginosa to repeated rounds of swarming, a collective form of surface migration, drives remarkable parallel evolution toward a hyperswarmer phenotype. In all independently evolved hyperswarmers, the reproducible hyperswarming phenotype is caused by parallel point mutations in a flagellar synthesis regulator, FleN, which locks the naturally monoflagellated bacteria in a multiflagellated state and confers a growth rate-independent advantage in swarming. Although hyperswarmers outcompete the ancestral strain in swarming competitions, they are strongly outcompeted in biofilm formation, which is an essential trait for P. aeruginosa in environmental and clinical settings. The finding that evolution in swarming colonies reliably produces evolution of poor biofilm formers supports the existence of an evolutionary trade-off between motility and biofilm formation.