cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Hallazgos radiológicos tras cirugía conservadora mamaria utilizando malla de vicryl
Creators: name: Garcia Mur, Carmen
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Mammography
subject: MR
subject: Ultrasound
subject: Breast

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Analizar los hallazgos radiológicos en ecografía,
mamografía y resonancia magnética (RM) tras cirugía conservadora mamaria y colocación de malla de Vicryl en el lecho...
Joint Pedestrian Gesture Recognition and Orientation Estimation from Multistatic Radar Data
Creators: name: Kern, Nicolai
name: Badr, Ahmed
name: Grebner, Timo
name: Schoeder, Pirmin
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: automotive radar
subject: orientation estimation
subject: radar sensor networks
subject: DDC 620 / Engineering & allied operations
subject: Gesture recognition (Computer science)
subject: Neural networks (Computer science)
subject: Gestenerkennung
subject: Neuronales Netz

description: Radar-based detection of traffic gestures can play an important role in the interaction between autonomous vehicles (AVs) and vulnerable road users (VRUs). However, it is error-prone without information about the orientation of the VRU, from which the recipient of the gesture’s message can be inferred. Hence, this paper proposes a neural network with two output branches for joint gesture classification and orientation estimation. As input serve radar target lists derived from data measured by an incoherent radar sensor network. By training the whole model on a combined loss, the neural network simultaneously produces a gesture prediction and an orientation estimate. The proposed method is validated on a comprehensive dataset containing radar data over a broad range of orientations from 35 participants. On this dataset, it achieves a gesture recognition accuracy of 92.43 % and a mean orientation estimation error of 8.02°.
Étude de la conversion génique chez les familles multigéniques.
Creators: name: Prat, Frédéric.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Biology, Molecular.

description: Three multigene families have been studied from the point of view of gene conversion. The data sets included a group of plant actin genes from five different angiosperm species (maize, tomato, potato, soybean and tobacco), a group of primate globin genes (the $\delta$ and $\beta$ genes of human and tarsier, the $\gamma\sb1$ and $\gamma\sb2$ genes of human and orangutan) and a group of zinc finger genes (Zfx and Zfy), linked to the sex chromosomes of seven mammalian species (rat, mouse, fox, squirrel monkey, baboon, orangutan, human). The analysis was done by using four simulation methods and one compatibility method. The compatibility method is a variant of Fitch method (Fitch et al. 1990). The simulation methods include Sawyer's method (Sawyer 1989) and the codoubles method (Balding et al. 1992). To take into account the fact that different chromosomes may have different mutation rates, a variant of the codoubles method is introduced (the method of variable rates). All these methods are non specific and a method for specifically detecting areas of gene conversion is also introduced. Two conversion events were detected in the maize family. These results based exclusively on exons are confirmed by a high degree of sequence similarity between corresponding introns. The results obtained for the globin genes are in agreement with previous compatibility analyses and confirm the presence of gene conversion in this multigene family. In the case of the Zfx/Zfy genes, gene conversion was detected at a significant level for the rat and/or squirrel monkey lineages. Site by site analysis indicates that the conversion occurred probably in the primate lineage. soon after the separation of primates and rodents.
Uni Ulm intern - das Ulmer Universitätsmagazin, Nr. 257 (32. Jg.), November 2002
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Uni Ulm intern
subject: Universities; Germany; Ulm
subject: Ulm / Universität

description: N/A
An exploration of risk factors for aggression in relationships.
Creators: name: Jordan, Shelley A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Psychology, Social.

description: Violence in relationships is a serious social issue in our society. However, the developmental path that leads to this specific type of aggressive behaviour is unclear. The influence of familial factors, including violence in the family, parenting practices, lack of prosocial skills, and involvement in deviant peer groups, on the development of general aggression has been widely studied. Other research suggests that attachment bonds to parents are critical in the development of aggression, providing a role model for interactions in relationships and a foundation for intimacy, social development, and empathy. Further, adult attachment patterns that develop based on bonds with parents impact on how people interact in close relationships and are considered an important factor in sexual aggression and aggression in relationships. In addition to familial risk factors, interpersonal skills deficits, personality characteristics, negative influences of peers, and sexist attitudes may be important risk factors for aggression in relationships. The first purpose of the present study was to explore risk factors for aggression in the context of relationships. The second purpose was to compare groups of nonoffenders (students), nonviolent offenders, offenders violent outside of relationships, offenders violent within relationships, and offenders violent both within and outside of relationships with respect to familial variables, attachment styles, problem-solving skills, personality styles, influences of male peers, and sexist attitudes. The results indicated that family violence in childhood, poor attachment bonds with parents, interpersonal problem-solving deficits, insecure attachment styles in adulthood, abusive personality characteristics, negative influences from male peers, and sexist attitudes are important predictors of aggression in relationships. These risk factors also differentiated nonoffenders from offenders. However, the lack of differences among offender groups on these predictors points to a more general model of criminality, consistent with results of longitudinal studies with violent and nonviolent offenders. Implications in terms of parent training and early prevention with children at risk are discussed.
Neural signatures of bullying experience and social rejection in teenagers
Creators: name: Kiefer, Markus
name: Sim, Eun-Jin
name: Heil, Sabrina
name: Brown, Rebecca
name: Herrnberger, Bärbel
name: Spitzer, Manfred
name: Grön, Georg
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: PEER VICTIMIZATION
subject: PSYCHIATRIC-SYMPTOMS
subject: DEPRESSIVE SYMPTOMS
subject: SUBSTANCE USE
subject: EXCLUSION
subject: OSTRACISM
subject: Cingulate cortex
subject: DDC 150 / Psychology
subject: Peer group
subject: Adolescents
subject: Bullying
subject: Rejection, Psychology
subject: Neuroimaging
subject: Prefrontal cortex
subject: Mobbing
subject: Peer-Group
subject: Jugend
subject: Gehirn
subject: Bildgebendes Verfahren

description: Relational bullying in schools is one of the most frequent forms of violence and can have severe negative health impact, e.g. depression. Social exclusion is the most prominent form of relational bullying that can be operationalized experimentally. The present study used MR-based perfusion imaging (pCASL) to investigate the neural signatures of social exclusion and its relationship with individually different extent of previous bullying experience. Twenty-four teenagers reporting bullying experience at different extent were scanned during a virtual ball-tossing (Cyberball game). Our findings showed that social exclusion (relative to social inclusion) activated frontal brain areas: sub- and perigenual anterior cingulate cortex (sg/pgACC), left inferior frontal cortex (IFG), and dorsolateral prefrontal cortex. Positive relationship between exclusion-specific signal increase and individually different extents of prior bullying experience was for the first time observed in left IFG and sgACC. This suggests that more frequent prior experience has conditioned greater mentalizing and/or rumination, in order to cope with the situation. While this interpretation remains speculative, the present data show that the experience of being bullied partly sensitizes the neural substrate relevant for the processing of social exclusion.
title: Importancia de la ecografía en el diagnóstico diferencial del dolor escrotal.
Creators: name: Vicente Mérida, David
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Diagnostic procedure
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Genital / Reproductive system male
subject: Emergency

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El dolor escrotal agudo es un motivo de consulta relativamente frecuente en los servicios de Urgencia. La valoración clínica aislada puede ser insuficiente para obtener un diagnóstico preciso en algunos casos dado que diferentes tipos de...
Understanding feminist backlash through a fashionable framework: A content analysis of "Vogue" Magazine
Creators: name: Rutherford, Brooke
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Speech Communication.
subject: Mass Communications.

description: Drawing from feminist, post-modern and performative theory this investigation sets out to determine whether fashion is empowering or constraining for women in a period of US political backlash. Incorporating anthropological, historical, philosophical and sociological approaches the application of fashion in Vogue Magazine is assessed through a macroscopic content analysis using a systematic random sample methodology. Data is assessed according to twenty-three quantitative variables. A qualitative analysis determines the presence of subculture style, menswear fashion influences, functional fashion, work-suitability, and the relation of clothing in reference to the body. These conceptual variables answer the research question through tangible forms and demonstrate, in conjunction with theory, how fashion works as language to empower women. These findings indicate that in addition to providing women with means of subverting social constructions of gender, fashion and Vogue are catalysts for cultural change and work to neutralize the constraining movement that backlash politics imposed on the visibility of women.
Solving hard qualitative temporal reasoning problems: evaluating the efficiency of using the ORD-Horn class
Creators: name: Nebel, Bernhard
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Qualitative reasoning. Data processing
subject: Horn-Formel
subject: Qualitatives Schließen

description: N/A
KiDS-450: Testing extensions to the standard cosmological model
Creators: name: Joudaki, Shahab
name: Mead, Alexander
name: Blake, Chris
name: Choi, Ami
name: de Jong, Jelte
name: Erben, Thomas
name: Conti, Ian Fenech
name: Herbonnet, Ricardo
name: Heymans, Catherine
name: Hildebrandt, Hendrik
name: Hoekstra, Henk
name: Joachimi, Benjamin
name: Klaes, Dominik
name: Köhlinger, Fabian
name: Kuijken, Konrad
name: McFarland, John
name: Miller, Lance
name: Schneider, Peter
name: Viola, Massimo
Publisher: name: Swinburne
Year: 2024

description: We test extensions to the standard cosmological model with weak gravitational lensing tomography using 450 deg 2 of imaging data from the Kilo Degree Survey (KiDS). In these extended cosmologies, which include massive neutrinos, non-zero curvature, evolving dark energy, modified gravity and running of the scalar spectral index, we also examine the discordance between KiDS and cosmic microwave background (CMB) measurements from Planck. The discordance between the two data sets is largely unaffected by a more conservative treatment of the lensing systematics and the removal of angular scales most sensitive to non-linear physics. The only extended cosmology that simultaneously alleviates the discordance with Planck and is at least moderately favoured by the data includes evolving dark energy with a time-dependent equation of state (in the form of the w 0 - w a parametrization). In this model, the respective constraints agree at the 1σ level, and there is 'substantial concordance' between the KiDS and Planck data sets when accounting for the full parameter space. Moreover, the Planck constraint on the Hubble constant is wider than in Λ cold dark matter (ΛCDM) and in agreement with the Riess et al. (2016) direct measurement of H 0 . The dark energy model is moderately favoured as compared to ΛCDM when combining the KiDS and Planck measurements, and marginalized constraints in the w 0 -w a plane are discrepant with a cosmological constant at the 3σ level. KiDS further constrains the sum of neutrino masses to 4.0 eV (95% CL), finds no preference for time or scale-dependent modifications to the metric potentials, and is consistent with flatness and no running of the spectral index.
A sequential model for the structure of health care utilization
Creators: name: Herrmann, Wolfram J.
name: Haarmann, Alexander
name: Baerheim, Anders
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Traditional measurement models of health care utilization are not able to represent the complex structure of health care utilization. In this qualitative study, we, therefore, developed a new model to represent the health care utilization structure. In Norway and Germany, we conducted episodic interviews, participant observation and a concurrent context analysis. Data was analyzed by thematic coding in the framework of grounded theory. Consultations do very often not only have one single reason for encounter. They are usually not independent events but form part of consultation sequences. We could find structural differences between Norway and Germany regarding the flow of information between consultations and which providers are involved in health care in what way. This leads to a sequential model, in which health care utilization is seen as sequences of consultations. Such health care utilization sequences consist of nodes which are connected by edges. Nodes represent patient-provider contacts and edges depict the flow of information. Time and the level of health care providers are dimensions in the model. These sequences can be described by different measures and aggregated on population level. Thus, the sequential model can be further used in analyzing health care utilization quantitatively, e.g., by using routine data.
Chemicals and cell-based assays in drinking water sources in Manhiça, Mozambique
Creators: name: Villanueva, Cristina M.
name: Grau-Pujol, Berta
name: Grummt, Tamara
name: Evlampidou, Iro
name: Kuckelkorn, Jochen
Publisher: name: My University
Year: 2021
Subjects: Trinkwasser
Chemikalien
Mocambique

description: Background The chemical quality of drinking water is widely unknown in low-income countries. Objective We conducted an exploratory study in Manhiça district (Mozambique) to evaluate drinking water quality using chemical analyses and cell-based assays. Methods We measured nitrate, fluoride, metals, pesticides, disinfection by-products, and industrial organochlorinated chemicals, and conducted the bioassays Ames test for mutagenicity, micronuclei assay (MN-FACS), ER-CALUX, and antiAR-CALUX in 20 water samples from protected and unprotected sources. Results Nitrate was present in all samples (median 7.5â€ mg/L). Manganese, cobalt, chromium, aluminium, and barium were present in 90-100% of the samples, with median values of 32, 0.6, 2.0, 61, 250â€ (mirco)g/l, respectively. Manganese was above 50â€ ÎÌg/l (EU guideline) in eight samples. Arsenic, lead, nickel, iron, and selenium median values were below the quantification limit. Antimony, cadmium, copper, mercury, zinc and silver were not present. Trihalomethanes, haloacetic acids, haloacetonitriles and haloketones were present in 5-28% samples at levels =4.6â€ (micro)g/l. DDT, dieldrin, diuron, and pirimiphos-methyl were quantified in 2, 3, 3, and 1 sample, respectively (range 12-60â€ ng/L). Fluoride was present in one sample (0.11â€ mg/l). Trichloroethene and tetrachloroethene were not present. Samples were negative in the in vitro assays. Significance Results suggest low exposure to chemicals, mutagenicity, genotoxicity and endocrine disruption through drinking water in Manhiça population. High concentration of manganese in some samples warrants confirmatory studies, given the potential link to impaired neurodevelopment. © 2021, The Author(s), under exclusive licence to Springer Nature America
Bubble Noir/Strange Spaces
Creators: name: Beckwith, Megan
name: White, Ben
Publisher: name: The University of Melbourne
Year: 2024
Subjects: classificationCode: 360499
subject: Performing arts not elsewhere classified

description: Bubble Noir/Strange Spaces is part of an ongoing series of performance installations, that take place in a bubble structure that serves as a dance partner and stage. Bubble Noir is a 30 minute contemporary dance drag installation featuring dancers Ben White and Megan Beckwith. Ben performs as the female protagonist, Axo Lotal and Megan as the male support role, Splana. The bubble serves as both a physical and metaphorical space, projected with glitched and stressed video elements derived from vintage Film Noir footage. This work interweaves dance, drag, a bubble environment and digital imagery for the Strange Spaces exhibition.In this work, Axo Lotal embodies the protagonist, grappling with themes of isolation and control, central to the Film Noir genre. Enclosed within the bubble, they face a series of existential questions: Will they escape? Can they find another breath? Or will the bubble ultimately burst? Choreographically the dance explores movement in a confined but shifting environment with the task of connecting with the moving imagery projected onto the bubble. Axo Lotal also becomes the subtext to the snippets of Film Noir imagery as the dancer's movements often seem to merge with the projected imagery, blurring the lines between human and digital. While Axo Lotal grapples with her immediacy, Splana through a desire to prove a point, offends everyone.
Floral cues of non-host plants attract oligolectic chelostoma rapunculi bees
Creators: name: Burger, Hannah
name: Joos, Nadine
name: Ayasse, Manfred
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Floral scent
subject: Spiroacetals
subject: Pollen-specialist bee
subject: DDC 570 / Life sciences
subject: DDC 580 / Botanical sciences
subject: Flowers Odor
subject: Color
subject: Campanula
subject: Malva
subject: Geraniums
subject: color
subject: Malve

description: Oligolectic bees are highly dependent on the availability of the host plants to which they are specialized. Nevertheless, females of Chelostoma rapunculi have recently been monitored occasionally to visit Malva moschata and Geranium sanguineum flowers, in addition to their well-known Campanula spp. hosts. The questions therefore arise which floral cues promote visits to non-host plants. As host-specific floral cues are key attractants for oligolectic bees, we have studied the attractiveness of olfactory and visual cues of the established host Campanula trachelium in comparison to the non-host plants G. sanguineum and M. moschata in behavioral experiments. Chemical and electrophysiological analyses of the floral scent and spectral measurements of floral colors were used to compare and contrast host and non-host plants. The behavioral experiments showed that foraging-naïve bees, in particular, were attracted by olfactory cues of the non-host plants, and that they did not favor the Campanula host scent in choice experiments. Many electrophysiologically active floral volatiles were present in common in the studied plants, although each species produced an individual scent profile. Spiroacetals, the key components that enable C. rapunculi to recognize Campanula hosts, were detected in trace amounts in Geranium but could not be proved to occur in Malva. The visual floral cues of all species were particularly attractive for foraging-experienced bees. The high attractiveness of G. sanguineum and M. moschata flowers to C. rapunculi bees and the floral traits that are similar to the Campanula host plants can be a first step to the beginning of a host expansion or change which, however, rarely occurs in oligolectic bees.
Numerical analysis and investigation of the interaction between fluid and multiple bodies
Creators: name: Mohammadhosseini, Negar
Publisher: name: Swinburne
Year: 2024

description: Every corner of the world is surrounded by structures and fluids. This inevitable interaction of these two base substances encompasses a series of phenomena that are important in a wide range of natural and man-made situations. Research in this field has been mostly limited to the interaction of the fluid flow and two cylindrical structures due to the complexity of the occurred phenomena and wide range of involved parameters. This research aims at gaining a better understanding and finding a framework of interaction between fluid and multiple structures.
Can untreated PKU patients escape from intellectual disability? A systematic review
Creators: name: Van Vliet, Danique
name: Van Wegberg, Annemiek M J
name: Ahring, Kirsten
name: Bik-Multanowski, Miroslaw
name: Blau, Nenad
name: Bulut, Fatma D
name: Casas, Kari
name: Didycz, Bozena
name: Djordjevic, Maja
name: Federico, Antonio
name: Feillet, François
name: Gizewska, Maria
name: Gramer, Gwendolyn
name: Hertecant, Jozef L
name: Hollak, Carla E M
name: Jørgensen, Jens V
name: Karall, Daniela
name: Landau, Yuval
name: Leuzzi, Vincenzo
name: Mathisen, Per
name: Moseley, Kathryn
name: Mungan, Neslihan Ö
name: Nardecchia, Francesca
name: Õunap, Katrin
name: Powell, Kimberly K
name: Ramachandran, Radha
name: Rutsch, Frank
name: Setoodeh, Aria
name: Stojiljkovic, Maja
name: Trefz, Fritz K
name: Usurelu, Natalia
name: Wilson, Callum
name: Van Karnebeek, Clara D
name: Hanley, William B
name: Van Spronsen, Francjan J
Publisher: name: BioMed Central
Year: 2018

description: Background: Phenylketonuria (PKU) is often considered as the classical example of a genetic disorder in which severe symptoms can nowadays successfully be prevented by early diagnosis and treatment. In contrast, untreated or late-treated PKU is known to result in severe intellectual disability, seizures, and behavioral disturbances. Rarely, however, untreated or late-diagnosed PKU patients with high plasma phenylalanine concentrations have been reported to escape from intellectual disability. The present study aimed to review published cases of such PKU patients. Methods: To this purpose, we conducted a literature search in PubMed and EMBASE up to 8th of September 2017 to identify cases with 1) PKU diagnosis and start of treatment after 7 years of age; 2) untreated plasma phenylalanine concentrations ≥1200 μmol/l; and 3) IQ ≥80. Literature search, checking reference lists, selection of articles, and extraction of data were performed by two independent researchers. Results: In total, we identified 59 published cases of patients with late-diagnosed PKU and unexpected favorable outcome who met the inclusion criteria. Although all investigated patients had intellectual functioning within the normal range, at least 19 showed other neurological, psychological, and/or behavioral symptoms. Conclusions: Based on the present findings, the classical symptomatology of untreated or late-treated PKU may need to be rewritten, not only in the sense that intellectual dysfunction is not obligatory, but also in the sense that intellectual functioning does not (re)present the full picture of brain damage due to high plasma phenylalanine concentrations. Further identification of such patients and additional analyses are necessary to better understand these differences between PKU patients.
Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop
Creators: name: Rockstroh, Alexandra
name: Moges, Beyene
name: Barzon, Luisa
name: Sinigaglia, Alessandro
name: Palu, Giorgio
name: Kumbukgolla, Widuranga
name: Schmidt-Chanasit, Jonas
name: Sarno, Manoel
name: Brites, Carlos
name: Moreira-Soto, Andres
name: Drexler, Jan Felix
name: Ferreira, Orlando C.
name: Ulbert, Sebastian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: dengue virus
subject: Zika virus
subject: diagnosis
subject: cross-reactivity
subject: ELISA
subject: envelope proteins
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods to specifically diagnose these infections and differentiate them from each other are mandatory. However, serological assays for flaviviruses in general, and for DENV and ZIKV in particular, are compromised by the high degree of similarities in their proteins which can lead to cross-reacting antibodies and false-positive test results. Cross- reacting flavivirus antibodies mainly target the highly conserved fusion loop (FL) domain in the viral envelope (E-) protein, and we and others have shown previously that recombinant E-proteins bearing FL-mutations strongly reduce cross-reactivity. Here we investigate whether such mutant E-proteins can be used to specifically detect antibodies against DENV and ZIKV in an ELISA- format. IgM antibodies against DENV and ZIKV virus were detected with 100% and 94.2% specificity and 90.7% and 87.5% sensitivity, respectively. For IgG the mutant E-proteins showed cross-reactivity, which was overcome by pre- incubation of the sera with the heterologous antigen. This resulted in specificities of 97.1% and 97.9% and in sensitivities of 100% and 100% for the DENV and ZIKV antigens, respectively. Our results suggest that E-proteins bearing mutations in the FL-domain have a high potential for the development of serological DENV and ZIKV tests with high specificity.
Iota-carrageenan inhibits replication of SARS-CoV-2 and the respective variants of concern alpha, beta, gamma and delta
Creators: name: Fröba, Maria
name: Große, Maximilian
name: Setz, Christian
name: Rauch, Pia
name: Auth, Janina
name: Spanaus, Lucas
name: Münch, Jan
name: Ruetalo, Natalia
name: Schindler, Michael
name: Morokutti-Kurz, Martina
name: Graf, Philipp
name: Prieschl-Grassauer, Eva
name: Grassauer, Andreas
name: Schubert, Ulrich
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: coronavirus
subject: pseudotyping
subject: iota-carrageenan
subject: kappa-carrageenan
subject: lambda-carrageenan
subject: sulfated polymer
subject: virus variants
subject: variants of concern
subject: carrageenan types
subject: DDC 540 / Chemistry & allied sciences
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: COVID-19
subject: SARS-CoV-2
subject: Carrageenan
subject: Genetic therapy
subject: COVID-19
subject: SARS-CoV-2
subject: Carrageenane
subject: Gentherapie

description: The COVID-19 pandemic continues to spread around the world and remains a major public health threat. Vaccine inefficiency, vaccination breakthroughs and lack of supply, especially in developing countries, as well as the fact that a non-negligible part of the population either refuse vaccination or cannot be vaccinated due to age, pre-existing illness or non-response to existing vaccines intensify this issue. This might also contribute to the emergence of new variants, being more efficiently transmitted, more virulent and more capable of escaping naturally acquired and vaccine-induced immunity. Hence, the need of effective and viable prevention options to reduce viral transmission is of outmost importance. In this study, we investigated the antiviral effect of iota-, lambda- and kappa-carrageenan, sulfated polysaccharides extracted from red seaweed, on SARS-CoV-2 Wuhan type and the spreading variants of concern (VOCs) Alpha, Beta, Gamma and Delta. Carrageenans as part of broadly used nasal and mouth sprays as well as lozenges have the potential of first line defense to inhibit the infection and transmission of SARS-CoV-2. Here, we demonstrate by using a SARS-CoV-2 spike pseudotyped lentivirus particles (SSPL) system and patient-isolated SARS-CoV-2 VOCs to infect transgenic A549ACE2/TMPRSS2 and Calu-3 human lung cells that all three carrageenan types exert antiviral activity. Iota-carrageenan exhibits antiviral activity with comparable IC50 values against the SARS-CoV-2 Wuhan type and the VOCs. Altogether, these results indicate that iota-carrageenan might be effective for prophylaxis and treatment of SARS-CoV-2 infections independent of the present and potentially future variants.
Adoptive transfer of M2 macrophages reduces neuropathic pain via opioid peptides
Creators: name: Pannell, Maria
name: Labuz, Dominika
name: Celik, Melih O.
name: Keye, Jacqueline
name: Batra, Arvind
name: Siegmund, Britta
name: Machelska, Halina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Macrophage
subject: Neuropathic pain
subject: Enkephalin
subject: Dynorphin
subject: Endorphin
subject: Analgesia
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background During the inflammation which occurs following nerve damage, macrophages are recruited to the site of injury. Phenotypic diversity is a hallmark of the macrophage lineage and includes pro-inflammatory M1 and anti- inflammatory M2 populations. Our aim in this study was to investigate the ability of polarized M0, M1, and M2 macrophages to secrete opioid peptides and to examine their relative contribution to the modulation of neuropathic pain. Methods Mouse bone marrow-derived cells were cultured as unstimulated M0 macrophages or were stimulated into an M1 phenotype using lipopolysaccharide and interferon-γ or into an M2 phenotype using interleukin-4. The macrophage phenotypes were verified using flow cytometry for surface marker analysis and cytokine bead array for cytokine profile assessment. Opioid peptide levels were measured by radioimmunoassay and enzyme immunoassay. As a model of neuropathic pain, a chronic constriction injury (CCI) of the sciatic nerve was employed. Polarized M0, M1, and M2 macrophages (5 × 105 cells) were injected perineurally twice, on days 14 and 15 following CCI or sham surgery. Mechanical and heat sensitivity were measured using the von Frey and Hargreaves tests, respectively. To track the injected macrophages, we also transferred fluorescently stained polarized cells and analyzed the surface marker profile of endogenous and injected cells in the nerves ex vivo. Results Compared to M0 and M1 cells, M2 macrophages contained and released higher amounts of opioid peptides, including Met-enkephalin, dynorphin A (1–17), and β-endorphin. M2 cells transferred perineurally at the nerve injury site reduced mechanical, but not heat hypersensitivity following the second injection. The analgesic effect was reversed by the perineurally applied opioid receptor antagonist naloxone methiodide. M2 cells did not affect sensitivity following sham surgery. Neither M0 nor M1 cells altered mechanical and heat sensitivity in CCI or sham-operated animals. Tracing the fluorescently labeled M0, M1, and M2 cells ex vivo showed that they remained in the nerve and preserved their phenotype. Conclusions Perineural transplantation of M2 macrophages resulted in opioid-mediated amelioration of neuropathy-induced mechanical hypersensitivity, while M1 macrophages did not exacerbate pain. Therefore, rather than focusing on macrophage-induced pain generation, promoting opioid-mediated M2 actions may be more relevant for pain control.
Supplementary document for Mid-infrared resonant cavity light emitting diodes for N2O gas detection at 4.5 µm - 4673335.pdf
Creators: name: Krier, Anthony
name: Al-Saymari, Furat
name: Craig, Adam
name: Lu, Qi
name: Marshall, Andrew
name: Carrington, Peter
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: SEM image
Gleichstellungsbericht 2019
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Universität Ulm ; Gleichberechtigung
subject: DDC 300 / Social sciences
subject: Women in higher education
subject: Women in science; Germany; Ulm; University
subject: Sex discrimination in higher education
subject: Gleichstellung

description: Gleichstellungsbericht der Universität Ulm 2019
Antibody response to pneumococcal and influenza vaccination in patients with rheumatoid arthritis receiving abatacept
Creators: name: Alten, Rieke
name: Bingham, Clifton O.
name: Cohen, Stanley B.
name: Curtis, Jeffrey R.
name: Kelly, Sheila
name: Wong, Dennis
name: Genovese, Mark C.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Abatacept
subject: Influenza
subject: Pneumococcal
subject: Rheumatoid arthritis
subject: Vaccination
subject: Immunization
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Patients with rheumatoid arthritis (RA), including those treated with biologics, are at increased risk of some vaccine-preventable infections. We evaluated the antibody response to standard 23-valent pneumococcal polysaccharide vaccine (PPSV23) and the 2011–2012 trivalent seasonal influenza vaccine in adults with RA receiving subcutaneous (SC) abatacept and background disease-modifying anti-rheumatic drugs (DMARDs). Methods Two multicenter, open-label sub-studies enrolled patients from the ACQUIRE (pneumococcal and influenza) and ATTUNE (pneumococcal) studies at any point during their SC abatacept treatment cycle following completion of ≥3 months’ SC abatacept. All patients received fixed-dose abatacept 125 mg/week with background DMARDs. A pre-vaccination blood sample was taken, and after 28 ± 3 days a final post- vaccination sample was collected. The primary endpoint was the proportion of patients achieving an immunologic response to the vaccine at Day 28 among patients without a protective antibody level to the vaccine antigens at baseline (pneumococcal: defined as ≥2-fold increase in post-vaccination titers to ≥3 of 5 antigens and protective antibody level of ≥1.6 μg/mL to ≥3 of 5 antigens; influenza: defined as ≥4-fold increase in post-vaccination titers to ≥2 of 3 antigens and protective antibody level of ≥1:40 to ≥2 of 3 antigens). Safety and tolerability were evaluated throughout the sub-studies. Results Pre- and post-vaccination titers were available for 113/125 and 186/191 enrolled patients receiving the PPSV23 and influenza vaccine, respectively. Among vaccinated patients, 47/113 pneumococcal and 121/186 influenza patients were without protective antibody levels at baseline. Among patients with available data, 73.9 % (34/46) and 61.3 % (73/119) met the primary endpoint and achieved an immunologic response to PPSV23 or influenza vaccine, respectively. In patients with pre- and post-vaccination data available, 83.9 % in the pneumococcal study demonstrated protective antibody levels with PPSV23 (titer ≥1.6 μg/mL to ≥3 of 5 antigens), and 81.2 % in the influenza study achieved protective antibody levels (titer ≥1:40 to ≥2 of 3 antigens) at Day 28 post-vaccination. Vaccines were well tolerated with SC abatacept with background DMARDs. Conclusions In these sub-studies, patients with RA receiving SC abatacept and background DMARDs were able to mount an appropriate immune response to pneumococcal and influenza vaccines. Trial registration NCT00559585 (registered 15 November 2007) and NCT00663702 (registered 18 April 2008).
Wissenschaftlich fachliche Unterstützung der Nationalen Wasserstrategie - Kohärenz der flächenbezogenen Gewässerentwicklungsplanung gemäß WRRL mit der Raumplanung
Creators: name: Janssen, Gerold
name: Koenzen, Uwe
Publisher: name: Umweltbundesamt
Year: 2022
Subjects: Wasserwirtschaft
Wasserhaushaltsgesetz
Raumordnungsgesetz
Raumordnung
Regionalplanung
Bauleitplan

description: Um den ökologischen Zustand von Flüssen und Bächen zu verbessern und sie widerstandsfähiger gegenüber den Folgen des Klimawandels zu machen, benötigen sie mehr Fläche. Welchen Beitrag leistet die Raumordnung, Bauleitplanung und die wasserwirtschaftliche Planung, wenn es darum geht Flächen für die Gewässerentwicklung zu sichern? Wie können diese rechtlichen Instrumente dahingehend optimiert und besser aufeinander abgestimmt werden? Antworten auf diese Fragen und Empfehlungen liefert die vorliegende Publikation. Im Ergebnis gibt es sowohl auf der Seite der Raumordnung als auch der wasserwirtschaftlichen Fachplanung einen inhaltlichen sowie verfahrensrechtlichen Anpassungsbedarf, der entsprechend konkretisiert wird. Quelle: www.umweltbundesamt.de
An empowering climate as a protective factor against sexual violence in sport?
Creators: name: Ohlert, Jeannine
name: Schmitz, Helena
name: Schäfer-Pels, Alina
name: Allroggen, Marc
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: sexual violence
subject: empowering climate
subject: disempowering climate
subject: motivational climate
subject: power relations
subject: hierarchy
subject: elite sport
subject: DDC 150 / Psychology
subject: DDC 300 / Social sciences
subject: Sex crimes
subject: Interpersonal violence
subject: Hierarchie

description: Background: From qualitative studies with survivors of sexual violence, it is known that two important risk factors for sexual violence are unequal power relations and strong hierarchies; the concept of an empowering climate works against these risk factors and might thus serve as a factor in preventing experiences of sexual violence among athletes. The aim of the current study was to examine the relationship between an empowering climate within a sport group and experiences of sexual violence. Methods: In total, 644 athletes took part in an online survey measuring their perceptions of the empowering climate within their training group and their observations and experiences of sexual violence within the same group. MANOVAs were used to examine differences in perception of the empowering climate between those athletes who had observed or experienced sexual violence and those who had not. Results: The results reveal that athletes who had experienced or observed sexual violence rated the empowering climate subfactors within their training group as lower and the disempowering climate subfactors as higher. Conclusions: This study supports findings from prior qualitative studies and hints that a climate high in empowerment and low in disempowerment might be a protective factor against sexual violence in sport groups.
Supplementary document for Low-loss, centimeter-scale plasmonic metasurface for ultrafast optoelectronics - 4674459.pdf
Creators: name: Traverso, Andrew
name: Huang, Jiani
name: Peyronel, Thibault
name: Yang, Guoce
name: Tiecke, Tobias
name: Mikkelsen, Maiken H.
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary material for publication
Dual-focused Transformational Leadership and Service Innovation in the Context of Chinese Hospitality Industry
Creators: name: Yang, Mingjun
Publisher: name: Swinburne
Year: 2024

description: Alongside Chinese social and economic development, Chinese people are now better able to enjoy leisure activities such as dining at restaurants and spending spare time in hotels. Therefore, the Chinese hospitality industry is confronted with the challenge that Chinese customers have an increasing demand for high-quality service. Service innovation contributes to improving service quality and customer satisfaction, contributing to gaining competitive advantages in China's rapidly developing society. This study provides practical insights to Chinese hospitality practitioners that how to adopt dual-focused transformational leadership behaviours to respectively team-level service innovation and individual service innovative behaviour, contributing to business success.
Multi-source fusion operations in subjective logic
Creators: name: Kopp, Henning
name: Kargl, Frank
name: Van Der Heijden, Rens Wouter
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Fusion
subject: Subjective logic
subject: Multi-source fusion
subject: DDC 004 / Data processing & computer science
subject: DDC 620 / Engineering & allied operations
subject: Information theory in mathematics
subject: Logic, Symbolic and mathematical

description: This is the presentation of our paper, multi-source fusion operations in subjective logic.
Development of polyphenylene oxide and modified polyphenylene oxide membranes for dehydration of methane
Creators: name: Mortazavi, Saviz
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Engineering, Chemical.

description: The objective of this study was to systematically evaluate the suitability of polyphenylene oxide (PPO) and modified PPO as membrane material for separation of water vapor from methane gas. The objectives of the study also included the study of structure and performance relationship of both PPO and modified PPO in relation to separation of water vapor and methane mixture as well as the permeation of single gases. In particular, modification of PPO was achieved via sulfonation and bromination of the aromatic ring in the backbone of the polymer to various degrees of substitution. Two high molecular weight PPO polymers with intrinsic viscosities of 1.58 dL/g and 1.79 dL/g were chemically modified via addition of bromine (PPOBr) through aryl bromination; with degrees of substitution of up to 98% via addition of sulfonate groups (SPPO); with ion exchange capacities (IEC) of as high as 2.07 meq/g dry polymer, through aryl substitution and sequential addition of bromine and sulfonate substituents (SPPOBr) to the PPO backbone, followed by conversion of the sulfonate groups (-SO3H) to its sodium form (NaSPPO and NaSPPOBr) and dense homogeneous films were cast and tested. The results indicated that in the NaSPPO mutual interactions of water and methane and their interaction with the film material are dominating factors in their transport. The decrease in methane permeability was a result of increased water cluster size and increased interaction of water and methane. The permeability of water vapor showed an initial increase in NaSPPO films up to IEC of 1.69, followed by a decrease with increasing IEC. The decrease in water permeability was attributed to increased water-water and water-polymer interactions. In methane and water separation experiments the dominating factors were both the sieving effect of the material (diffusivity) and the interaction of the polymer with the penetrating species (solubility). In addition to these factors, the interaction between methane and water was found to further contribute to increased selectivity that was observed in these films. (Abstract shortened by UMI.)
KiDS-450: The tomographic weak lensing power spectrum and constraints on cosmological parameters
Creators: name: Köhlinger, F.
name: Viola, M.
name: Joachimi, B.
name: Hoekstra, H.
name: van Uitert, E.
name: Hildebrandt, H.
name: Choi, A.
name: Erben, T.
name: Heymans, C.
name: Joudaki, Shahab
name: Klaes, D.
name: Kuijken, K.
name: Merten, J.
name: Miller, L.
name: Schneider, P.
name: Valentijn, E. A.
Publisher: name: Swinburne
Year: 2024

description: We present measurements of the weak gravitational lensing shear power spectrum based on 450 deg 2 of imaging data from the Kilo Degree Survey. We employ a quadratic estimator in two and three redshift bins and extract band powers of redshift autocorrelation and crosscorrelation spectra in the multipole range 76 ≤ ℓ ≤ 1310. The cosmological interpretation of the measured shear power spectra is performed in a Bayesian framework assuming a ΛCDM model with spatially flat geometry, while accounting for small residual uncertainties in the shear calibration and redshift distributions as well as marginalizing over intrinsic alignments, baryon feedback and an excess-noise power model. Moreover, massive neutrinos are included in the modelling. The cosmological main result is expressed in terms of the parameter combination yielding S 8 =0.651±0.058 (three z-bins), confirming the recently reported tension in this parameter with constraints from Planck at 3.2σ (three z-bins). We cross-check the results of the three z-bin analysis with the weaker constraints from the two z-bin analysis and find them to be consistent.
Supplementary document for Low-loss, centimeter-scale plasmonic metasurface for ultrafast optoelectronics - 4674459.pdf
Creators: name: Traverso, Andrew
name: Huang, Jiani
name: Peyronel, Thibault
name: Yang, Guoce
name: Tiecke, Tobias
name: Mikkelsen, Maiken H.
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Uncategorized

description: Supplementary material for publication
Internet als Kooperations- und Lernmedium: neue Lernformen in der wissenschaftsfundierten Weiterbildung Älterer
Creators: name: Stadelhofer, Carmen
name: Marquard, Markus
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 370 / Education
subject: Education of adults
subject: Learning; In old age
subject: Altenbildung
subject: Internet
subject: Online-Publikation
subject: Ringvorlesung

description: Am Beispiel der Aktivitäten des Vereins "Virtuelles und reales Lern- und Kompetenznetzwerk älterer Erwachsener (ViLE) e.V.", der bundesweiten Online-Ringvorlesung der BAG WiWA, der intergenerationellen europäischen Online-Vorlesung "Wege und Werte entlang der Donau" sowie virtueller Leseprojekte werden unterschiedliche Konzepte und didaktische Prinzipien virtuellen Lernens in Bezug auf die Interessen, Bedarfe und Motivationen älterer Lernender aufgezeigt und diskutiert.