cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Buchdahl quark stars within $f(Q)$ theory
Creators: name: Sokoliuk, Oleksii
name: Pradhan, Sneha
name: Sahoo, P. K.
name: Baransky, Alexander
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the present paper, authors study the strange stars with the MIT Bag EoS admitting Buchdahl symmetry (non-singular and physically viable metric potential) in the both linear $f(Q)=aQ+b$ and non-linear $f(Q)=Q+aQ^b$ forms of modified symmetric teleparallel gravitation. In order to obtain the correct form of Buchdahl metric coefficients, they matched interior strange star spacetime with the exterior Schwarzschild vacuum spacetime. As a strange star candidate, PSRJ1416-2230 has been used with mass $M=1.69M_\odot$ and radius $R=9.69R_\odot$. For either linear and non-linear $f(Q)$ gravities, they probed Null, Dominant and Strong Energy Conditions as well as the radial, tangential Equation of State (EoS), gradients of the perfect fluid energy-momentum tensor elements, Tolman-Oppenheimer-Volkoff equilibrium condition, relativistic adiabatic index and causality conditions, surface redshift. It was found that strange stars in the linear and non-linear $f(Q)$ gravity show physically viable behavior, respect energy and causality conditions, has EoS in the bounds $0\leqω\leq1$ and surface redshift does not exceed 2, as expected.
description: EPJ Plus published version
A Digital Twin for PI-store Automated Warehouses
Creators: name: Rebuglio, Massimo
name: Ferrari, Andrea
name: Zenezini, Giovanni
name: Carlin, Antonio
name: Rafele, Carlo
Publisher: name: Georgia Institute of Technology
Year: 2023
Subjects: Digital twin
Automated storage and retrieval systems
Laboratory
Discrete-event simulation

description: Presented at the 9th International Physical Internet Conference (IPIC 2023) 13-15 June 2023, Athens, Greece
description: AS/RS studies focus on optimization and analytical models. However, analytical evaluation often consider deterministic and stable input parameters which are not necessarily found in real-life AS/RS systems. Cyber-physical systems such as Digital Twins represent a way to generate better predictive performance measures for a given system configuration.
Additional file 1 of The conceptualisation of cardiometabolic disease policy model in the UK
Creators: name: Putri, Septiara
name: Ciminata, Giorgio
name: Lewsey, Jim
name: Jani, Bhautesh
name: McMeekin, Nicola
name: Geue, Claudia
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Supplementary Material 1
Microgavage of Zebrafish Larvae
Creators: name: Cocchiaro, Jordan L.
name: Rawls, John F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The zebrafish has emerged as a powerful model organism for studying intestinal development1-5, physiology6-11, disease12-16, and host-microbe interactions17-25. Experimental approaches for studying intestinal biology often require the in vivo introduction of selected materials into the lumen of the intestine. In the larval zebrafish model, this is typically accomplished by immersing fish in a solution of the selected material, or by injection through the abdominal wall. Using the immersion method, it is difficult to accurately monitor or control the route or timing of material delivery to the intestine. For this reason, immersion exposure can cause unintended toxicity and other effects on extraintestinal tissues, limiting the potential range of material amounts that can be delivered into the intestine. Also, the amount of material ingested during immersion exposure can vary significantly between individual larvae26. Although these problems are not encountered during direct injection through the abdominal wall, proper injection is difficult and causes tissue damage which could influence experimental results.We introduce a method for microgavage of zebrafish larvae. The goal of this method is to provide a safe, effective, and consistent way to deliver material directly to the lumen of the anterior intestine in larval zebrafish with controlled timing. Microgavage utilizes standard embryo microinjection and stereomicroscopy equipment common to most laboratories that perform zebrafish research. Once fish are properly positioned in methylcellulose, gavage can be performed quickly at a rate of approximately 7-10 fish/ min, and post-gavage survival approaches 100% depending on the gavaged material. We also show that microgavage can permit loading of the intestinal lumen with high concentrations of materials that are lethal to fish when exposed by immersion. To demonstrate the utility of this method, we present a fluorescent dextran microgavage assay that can be used to quantify transit from the intestinal lumen to extraintestinal spaces. This test can be used to verify proper execution of the microgavage procedure, and also provides a novel zebrafish assay to examine intestinal epithelial barrier integrity under different experimental conditions (e.g. genetic manipulation, drug treatment, or exposure to environmental factors). Furthermore, we show how gavage can be used to evaluate intestinal motility by gavaging fluorescent microspheres and monitoring their subsequent transit. Microgavage can be applied to deliver diverse materials such as live microorganisms, secreted microbial factors/toxins, pharmacological agents, and physiological probes. With these capabilities, the larval zebrafish microgavage method has the potential to enhance a broad range of research fields using the zebrafish model system.
Additional file 1 of Socio-cultural factors influencing adolescent pregnancy in Ghana: a scoping review
Creators: name: Amoadu, Mustapha
name: Ansah, Edward Wilson
name: Assopiah, Patricia
name: Acquah, Philomina
name: Ansah, Joyce Evelyn
name: Berchie, Eunice
name: Hagan, Doris
name: Amoah, Elsie
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1.
Additional file 3 of Prevalence, risk factors, and characterisation of extended-spectrum β-lactamase -producing Enterobacterales (ESBL-E) in horses entering an equine hospital and description of longitudinal excretion
Creators: name: Eskola, Katarina
name: Aimo-Koivisto, Elina
name: Heikinheimo, Annamari
name: Mykkänen, Anna
name: Hautajärvi, Tiina
name: Grönthal, Thomas
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Additional file 3. Questionnaire (translated from Finnish to English) for determining risk factors for extended-spectrum β-lactamase -producing Enterobacterales (ESBL-E) carriage in admitted horses at the Equine Veterinary Teaching Hospital
Hyperconnected and Autonomous Distribution System for Societally Critical Products
Creators: name: Shaikh, Sahrish Jaleel
name: Pothen, Ashwin
name: Montreuil, Benoit
Publisher: name: Georgia Institute of Technology
Year: 2023
Subjects: Physical internet
Hyperconnected distribution
Autonomous operating systems
Multi-agent systems
Societally critical products
Personal protection equipment

description: Presented at the 9th International Physical Internet Conference (IPIC 2023) 13-15 June 2023, Athens, Greece
description: Societally critical products are crucial for maintaining people's well-being and ensuring the continuity of vital societal operations. However, disruptions can severely impact their supply chains due to increased demand and supply chain disruptions. The Paper defines the importance of these products and presents a conceptual framework for a hyperconnected and autonomous distribution system that encompasses physical, organizational, information, and operational aspects. We present the results of research at Georgia Tech during the COVID19 pandemic, which involved designing and operating an innovative system for efficiently distributing personal protection equipment. The study provides the foundation for a systemic approach to distributing societally critical products, integrating autonomous operations and hyperconnectivity based on Physical Internet concepts. The Paper also discusses the challenges of large-scale adoption, implementation, and operation of such a distribution system.
Automated high-speed Hyperloop cargo transportation for a sustainable logistics network
Creators: name: Eschment, Lukas
name: Duin, Heiko
name: Nobel, Thomas
name: Tolujevs, Jurijs
name: Wurst, Stephan
name: Yatskiv, Irina
name: Schüning, Thomas
name: Neu, Walter
Publisher: name: Georgia Institute of Technology
Year: 2023
Subjects: Hyperloop
Low-pressure tube transport
Cross-docking
DES
Modelling
LCPA
Automation
Tube network

description: Presented at the 9th International Physical Internet Conference (IPIC 2023) 13-15 June 2023, Athens, Greece
description: Hyperloop cargo transportation in an evolving Physical Internet does have the potential to contribute major advances in sustainable, high-speed freight transport. The low-pressure tube transport (LPTT) solution realistically enables a viable zero-emission high-speed transport system to come to market quickly with rather low levels of investment in infrastructure. Switching and merging technologies for cargo pods are the key to a LPTT network, providing much greater flexibility for the TEN-T network. The integration into intermodal cross-docking hubs including the use of standardized transport units and synchromodal algorithms predicting and distributing transport flows is a key characteristic for the success of the implementation of new and more environmentally friendly transport modes to the Physical Internet. Modelling and simulation as well as Life-cycle performance assessment for an industrial use case supplying an ingrown industrial area in an urban environment highlights the benefits of a LPTT connection between an ePI node and an automotive plant.
Machine Learning and Analytical Power Consumption Models for 5G Base Stations
Creators: name: Piovesan, Nicola
name: Lopez-Perez, David
name: De Domenico, Antonio
name: Geng, Xinli
name: Bao, Harvey
name: Debbah, Merouane
Publisher: name: arXiv
Year: 2022
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The energy consumption of the fifth generation(5G) of mobile networks is one of the major concerns of the telecom industry. However, there is not currently an accurate and tractable approach to evaluate 5G base stations (BSs) power consumption. In this article, we propose a novel model for a realistic characterisation of the power consumption of 5G multi-carrier BSs, which builds on a large data collection campaign. At first, we define a machine learning architecture that allows modelling multiple 5G BS products. Then, we exploit the knowledge gathered by this framework to derive a realistic and analytically tractable power consumption model, which can help driving both theoretical analyses as well as feature standardisation, development and optimisation frameworks. Notably, we demonstrate that such model has high precision, and it is able of capturing the benefits of energy saving mechanisms. We believe this analytical model represents a fundamental tool for understanding 5G BSs power consumption, and accurately optimising the network energy efficiency.
description: Accepted by IEEE Communications Magazine
Surfing the Physical Internet with Hyperconnected Logistics Networks
Creators: name: Grover, Nidhima
name: Shaikh, Sahrish Jaleel
name: Faugère, Louis
name: Montreuil, Benoit
Publisher: name: Georgia Institute of Technology
Year: 2023
Subjects: Physical Internet
Hyperconnected logistics
Freight transport
Logistics network design
Logistic hubs
Supply networks
Network design
Material handling
Modularization
Containerization
Omnichannel
E-commerce logistics
Modelling
Simulation

description: Presented at the 9th International Physical Internet Conference (IPIC 2023) 13-15 June 2023, Athens, Greece
description: The Physical Internet (PI) presents a transformative vision for logistics systems, where assets are shared openly, and flow consolidation is achieved through standardization, modularization, interfaces, and protocols. Hyperconnected logistics networks have emerged as a promising implementation of the PI, leveraging multi-tier meshed hubs and interconnectivity to achieve greater efficiency, resilience, and sustainability in the transportation of physical goods. However, a lack of clarity in the literature regarding the definition and design of hyperconnected logistics networks presents a significant obstacle to realizing their full potential. To address this gap, we propose a comprehensive definitional framework that integrates key concepts such as tiered network topology, hub interconnectivity, consolidation, and containerization. Moreover, we present a practical design approach for a hyperconnected logistics network in the United States, utilizing a representative demand scenario and accompanying network visualizations to enhance comprehension. Our research aims to unlock the potential of hyperconnected logistics networks as a crucial component of the PI, offering significant benefits to the global logistics industry and society as a whole.
The Stink beneath the Ink: How Cartoons Are Animating the Gay and Lesbian Culture Wars
Creators: name: Baiocchi, Frank
Publisher: name: Unknown
Year: 2006

description: Social problems can become the topic of national discourse through many different, indeterminable ways. There has been a recent surge in dialogue on the interpretation of cartoons that possibly reflect or promote gay and lesbian sensibilities. This dialogue has generated media attention and organized responses from social movements on both sides of the gay and lesbian culture war. The current article analyzes the social, political, and clinical implications of this national conversation. The work’s goal is to help social workers and policy makers understand how this conversation began, enabling them to explore where the dialogue might lead.
Using Coculture to Detect Chemically Mediated Interspecies Interactions
Creators: name: Shank, Elizabeth Anne
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: In nature, bacteria rarely exist in isolation; they are instead surrounded by a diverse array of other microorganisms that alter the local environment by secreting metabolites. These metabolites have the potential to modulate the physiology and differentiation of their microbial neighbors and are likely important factors in the establishment and maintenance of complex microbial communities. We have developed a fluorescence-based coculture screen to identify such chemically mediated microbial interactions. The screen involves combining a fluorescent transcriptional reporter strain with environmental microbes on solid media and allowing the colonies to grow in coculture. The fluorescent transcriptional reporter is designed so that the chosen bacterial strain fluoresces when it is expressing a particular phenotype of interest (i.e. biofilm formation, sporulation, virulence factor production, etc.) Screening is performed under growth conditions where this phenotype is not expressed (and therefore the reporter strain is typically nonfluorescent). When an environmental microbe secretes a metabolite that activates this phenotype, it diffuses through the agar and activates the fluorescent reporter construct. This allows the inducing-metabolite-producing microbe to be detected: they are the nonfluorescent colonies most proximal to the fluorescent colonies. Thus, this screen allows the identification of environmental microbes that produce diffusible metabolites that activate a particular physiological response in a reporter strain. This publication discusses how to: a) select appropriate coculture screening conditions, b) prepare the reporter and environmental microbes for screening, c) perform the coculture screen, d) isolate putative inducing organisms, and e) confirm their activity in a secondary screen. We developed this method to screen for soil organisms that activate biofilm matrix-production in Bacillus subtilis; however, we also discuss considerations for applying this approach to other genetically tractable bacteria.
Deep Brain Stimulation with Simultaneous fMRI in Rodents
Creators: name: Shih, Yen-Yu Ian
name: Younce, John Robert
name: Albaugh, Daniel L
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: In order to visualize the global and downstream neuronal responses to deep brain stimulation (DBS) at various targets, we have developed a protocol for using blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) to image rodents with simultaneous DBS. DBS fMRI presents a number of technical challenges, including accuracy of electrode implantation, MR artifacts created by the electrode, choice of anesthesia and paralytic to minimize any neuronal effects while simultaneously eliminating animal motion, and maintenance of physiological parameters, deviation from which can confound the BOLD signal. Our laboratory has developed a set of procedures that are capable of overcoming most of these possible issues. For electrical stimulation, a homemade tungsten bipolar microelectrode is used, inserted stereotactically at the stimulation site in the anesthetized subject. In preparation for imaging, rodents are fixed on a plastic headpiece and transferred to the magnet bore. For sedation and paralysis during scanning, a cocktail of dexmedetomidine and pancuronium is continuously infused, along with a minimal dose of isoflurane; this preparation minimizes the BOLD ceiling effect of volatile anesthetics. In this example experiment, stimulation of the subthalamic nucleus (STN) produces BOLD responses which are observed primarily in ipsilateral cortical regions, centered in motor cortex. Simultaneous DBS and fMRI allows the unambiguous modulation of neural circuits dependent on stimulation location and stimulation parameters, and permits observation of neuronal modulations free of regional bias. This technique may be used to explore the downstream effects of modulating neural circuitry at nearly any brain region, with implications for both experimental and clinical DBS.
Wave propagation through alumina-porous alumina laminates
Creators: name: Sellappan, Pathikumar
name: Wang, Erheng
name: Santos, Christian J. Espinoza
name: On, Tommy
name: Lambros, John
name: Kriven, Waltraud M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A Brazilian disk geometry of an alumina layered composite with alternating dense and porous layers was dynamically loaded using a Split-Hopkinson Pressure Bar (SHPB)apparatus under compression. High-speed imaging and transmitted force measurements were used to gain an insight into stress wave propagation and mitigation through such a layered system. Uniformly distributed porosities of 20 and 50 vol % were introduced into the interlayers by the addition of fine graphite particles which volatilized during heat treatment. Brazilian disk samples were cut from the cylinders which were drilled out of the sintered laminated sample. The disks were subjected to dynamic impact loading in perpendicular and parallel orientations to the layers in order to investigate the influence of the direction of impact. The dynamic failure process of the layered ceramic consisted of the initiation and propagation of the cracks mainly along the interphases of the layers. Upon impact, the impact energy was dissipated through fracture in parallel orientation (0 deg) but transmitted in perpendicular (90 deg) orientations. The high degree of correlation between the transmitted force, microstructure and orientation in which the layered systems were impacted is discussed.
description: 39 pages, 14 figures, 2 tables. Accepted for publication in the Journal of the European Ceramic Society
Framework for Leveraging Physical Internet Principles for Long Tail Products in E-Commerce
Creators: name: Meuche, Katja
name: Montreuil, Benoit
Publisher: name: Georgia Institute of Technology
Year: 2023
Subjects: E-commerce
Physical internet
Long tail
Sharing
Inventory management
Order fulfillment
Service level
Profitability
Sustainability

description: Presented at the 9th International Physical Internet Conference (IPIC 2023) 13-15 June 2023, Athens, Greece
description: The E-Commerce channel has led to the emergence of the long tail phenomenon describing products whose individual sales are low but collectively they contribute significantly to sales. Due to their low, lumpy, and intermittent demand characteristics, they pose extra challenges when retailers are confronted with product assortment, network wide inventory allocation, inventory deployment and order fulfillment with regards to the business goals of profitability, service levels and environmental sustainability. This Paper outlines how Physical Internet concepts can help to answer these challenges. By employing the four components of hyperconnected distribution and transportation, inventory sharing and information sharing, we propose a three-level framework that has the potential to promote profitability, customer satisfaction and sustainability for long-tail products.
Corpo sovrano e sovversione del corpo cristiano. Edward II tra amor ovidiano e mors paolina
Creators: name: Stella, Massimo
Publisher: name: La Rivista di Engramma
Year: 2023
Subjects: Marlowe
St Paul
Ovid
Freud
Shakespeare
Deleuze
Sacher Masoch
Edward II
Richard II
Hero and Leander
Sadomasochism
Kings Two Bodies

description: This essay is a re-reading of Christopher Marlowe’s Edward II in the light of St Paul’s Epistle to the Romans and the Ovidian paradigm of love as a metamorphic force, which Marlowe makes his own in the celebrated poem Hero and Leander. Building on the Christian notion of ‘natural body’, which, in the longue durée, underlies the Freudian conception of psychic drive, the essay also offers a methodological criticism of the Kantorowiczian conception of the king’s sacred body as well as of the Kantorowiczian understanding of William Shakespeare’s Richard II.
Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
Creators: name: Liu, Ming
name: Harper, Stephen
name: Huang, He
name: Lee, Michael
name: Zhang, Fan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: To enable intuitive operation of powered artificial legs, an interface between user and prosthesis that can recognize the user's movement intent is desired. A novel neural-machine interface (NMI) based on neuromuscular-mechanical fusion developed in our previous study has demonstrated a great potential to accurately identify the intended movement of transfemoral amputees. However, this interface has not yet been integrated with a powered prosthetic leg for true neural control. This study aimed to report (1) a flexible platform to implement and optimize neural control of powered lower limb prosthesis and (2) an experimental setup and protocol to evaluate neural prosthesis control on patients with lower limb amputations. First a platform based on a PC and a visual programming environment were developed to implement the prosthesis control algorithms, including NMI training algorithm, NMI online testing algorithm, and intrinsic control algorithm. To demonstrate the function of this platform, in this study the NMI based on neuromuscular-mechanical fusion was hierarchically integrated with intrinsic control of a prototypical transfemoral prosthesis. One patient with a unilateral transfemoral amputation was recruited to evaluate our implemented neural controller when performing activities, such as standing, level-ground walking, ramp ascent, and ramp descent continuously in the laboratory. A novel experimental setup and protocol were developed in order to test the new prosthesis control safely and efficiently. The presented proof-of-concept platform and experimental setup and protocol could aid the future development and application of neurally-controlled powered artificial legs.
Additional file 1 of Health promotion and disease prevention in the education of health professionals: a mapping of European educational programmes from 2019
Creators: name: Patja, Kristiina
name: Huis in ‘t Veld, Tessa
name: Arva, Dorottya
name: Bonello, Marjorie
name: Orhan Pees, Rana
name: Soethout, Marc
name: van der Esch, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Detailed version of Methods section (list of the approached informants and the questionnaire included). This document contains a detailed description of the methods used for this mapping alongside with the list of European Associations, examples of the national associations and numbers of national educational organisations approached as informants and the questionnaire developed for the mapping.
The ESO Science Archive
Creators: name: Romaniello, Martino
name: operations, the ESO Science Archive
name: team, development
Publisher: name: arXiv
Year: 2022
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The ESO Science Archive is the collection and access point of the data generated at ESO's La Silla Paranal Observatory, both raw and processed. It is a major contributor to ESO's science output, being used in about 4 out of 10 refereed articles with ESO data. In this paper, which is presented on behalf of the operations and development teams, we review its contents, policies, us interfaces and impact.
description: SPIE Astronomical Telescopes + Instrumentation 2022
Heavy Flavor Measurements at STAR
Creators: name: Vertesi, Robert
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We present a selection of recent heavy flavor results from the STAR experiment. Measurements of $D^0$ and $D^*$ meson production in $\sqrt{s}$=200 and 500 GeV p+p, as well as in $\sqrt{s_{NN}}$=200 GeV d+Au, Au+Au and 193 \GeV U+U collisions are presented and implications on the production mechanism are discussed. We report on the production and elliptic flow of electrons from semi-leptonic decays of heavy flavor hadrons in \snn{}=39, 62.4 and 200 GeV Au+Au collisions. Nuclear modification of $J/ψ$ production in $\sqrt{s_{NN}}$=39, 62.4 and 200 GeV Au+Au, and 193 GeV U+U, and of $Υ$ in 200 GeV d+Au, Au+Au, and 193 GeV U+U collisions are compared to theoretical models. Finally we discuss the prospects of heavy flavor measurements with the recent detector upgrades.
description: Submitted to Nucl. Phys. B Conf. Suppl. 7 pages, 13 figures
The Biopolitical Quest for Individuality as a Reactionary Device
Creators: name: Poloni, Marco
Publisher: name: Universita' degli Studi di Salerno
Year: 2020
Subjects: Governmentality
Psychopolitics
Symbolic exchange

description: With the advent of digitization and the affirmation of a symbolic value on social exchange within capital, public demonstrations of discontent are nowadays being performed along an aesthetic canon, thus losing their possible revolutionary potential. Once we internalized that it’s easier to imagine the end of the world than the end of capitalism, our struggles be-come individually symbolic and turn to aestheticism. Rather than stopping discontent, the power chooses to allow it because its performative content has already been neutralized. These demonstrations happen within a democratic culture – they play within the rules of the game. This is the imperial domination: to guarantee a resemblance of global peace for capi-tal to develop, at the price of local omni-crisis. If Empire is born and shows itself as crisis, this crisis is felt at every peripheral point of the Empire. Solutions of governmentality have worked until now, but at a cost: even though there still are cathartic events, they don't man-age release social tension completely – they always leave a mimetic residual. It's on those physical and psychological spaces of individual recognition that the Empire exercises its domination. And it’s there that forms of resistance can be tested.
Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy
Creators: name: Carson, Johnny L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Freeze-fracture/freeze-etch describes a process whereby specimens, typically biological or nanomaterial in nature, are frozen, fractured, and replicated to generate a carbon/platinum “cast” intended for examination by transmission electron microscopy. Specimens are subjected to ultrarapid freezing rates, often in the presence of cryoprotective agents to limit ice crystal formation, with subsequent fracturing of the specimen at liquid nitrogen cooled temperatures under high vacuum. The resultant fractured surface is replicated and stabilized by evaporation of carbon and platinum from an angle that confers surface three-dimensional detail to the cast. This technique has proved particularly enlightening for the investigation of cell membranes and their specializations and has contributed considerably to the understanding of cellular form to related cell function. In this report, we survey the instrument requirements and technical protocol for performing freeze-fracture, the associated nomenclature and characteristics of fracture planes, variations on the conventional procedure, and criteria for interpretation of freeze-fracture images. This technique has been widely used for ultrastructural investigation in many areas of cell biology and holds promise as an emerging imaging technique for molecular, nanotechnology, and materials science studies.
Array operators using multiple dispatch: a design methodology for array implementations in dynamic languages
Creators: name: Bezanson, Jeff
name: Chen, Jiahao
name: Karpinski, Stefan
name: Shah, Viral
name: Edelman, Alan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences
subject: D.3.3

description: Arrays are such a rich and fundamental data type that they tend to be built into a language, either in the compiler or in a large low-level library. Defining this functionality at the user level instead provides greater flexibility for application domains not envisioned by the language designer. Only a few languages, such as C++ and Haskell, provide the necessary power to define $n$-dimensional arrays, but these systems rely on compile-time abstraction, sacrificing some flexibility. In contrast, dynamic languages make it straightforward for the user to define any behavior they might want, but at the possible expense of performance. As part of the Julia language project, we have developed an approach that yields a novel trade-off between flexibility and compile-time analysis. The core abstraction we use is multiple dispatch. We have come to believe that while multiple dispatch has not been especially popular in most kinds of programming, technical computing is its killer application. By expressing key functions such as array indexing using multi-method signatures, a surprising range of behaviors can be obtained, in a way that is both relatively easy to write and amenable to compiler analysis. The compact factoring of concerns provided by these methods makes it easier for user-defined types to behave consistently with types in the standard library.
description: 6 pages, 2 figures, workshop paper for the ARRAY '14 workshop, June 11, 2014, Edinburgh, United Kingdom
Exploring the clinical utility of a brief screening measure of unmet supportive care needs in people with high-grade glioma
Creators: name: Campbell, Rachel
name: Faris, Mona
name: Shaw, Joanne
name: Halkett, Georgia KB
name: Legge, Dianne
name: Koh, Eng-Siew
name: Nowak, Anna K
name: Agar, Meera R
name: Ownsworth, Tamara
name: Pike, Kerryn
name: Chan, Raymond J
name: Dhillon, Haryana M
name: BRAINS, Program Grp
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 420310
subject: Health surveillance
classificationCode: 321104
subject: Cancer therapy (excl. chemotherapy and radiation therapy)

description: Background: People living with high-grade glioma (HGG) have diverse and complex needs. Screening aims to detect patients with some level of unmet need requiring triaging and further assessment. However, most existing measures of unmet need are not suitable for screening in this population due to their length. We aimed to explore the clinical utility of a brief screening tool (SCNS-ST9) in people with HGG in detecting unmet needs. Methods: Secondary analysis of data collected in a prospective cohort study of 116 people with HGG who completed the Supportive Care Needs Survey (SCNS-SF34) and a brain cancer-specific needs survey (BrTSCNS) during chemoradiation (T1) and 6 months later (T2). The SCNS-ST9 contains a subset of 9 items from the SCNS-SF34. Data analysis determined the number of individuals with unmet needs on the SCNS-SF34 and the BrTSCNS, not identified as having some level of need by the SCNS-ST9. Results: Overall, 3 individuals (T1: 2.6% [3/116]; T2: 4.8% [3/63]) at each time point reported other unmet needs on the SCNS-SF34 that were missed by the SCNS-ST9. Domain-specific screening items missed a higher proportion of individuals (3.2%-26%), particularly in the psychological and health systems domains. Only 1 individual with brain cancer-specific needs was missed by SCNS-ST9 overall. Conclusion: Findings demonstrate the sensitivity and clinical utility of a brief screening tool (SCNS-ST9) of unmet needs in people with HGG. Routine use of this screening tool, supported by clinical pathways, may improve access to support services, potentially reducing the burden of disease for these patients.
Additional file 2 of Health promotion and disease prevention in the education of health professionals: a mapping of European educational programmes from 2019
Creators: name: Patja, Kristiina
name: Huis in ‘t Veld, Tessa
name: Arva, Dorottya
name: Bonello, Marjorie
name: Orhan Pees, Rana
name: Soethout, Marc
name: van der Esch, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. List of countries. This document contains the list of the 31 WHO European Region countries from which educational programmes were included in the mapping.
Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
Creators: name: Adams, Andre A.
name: Boyd, Darryl A.
name: Daniele, Michael A.
name: Ligler, Frances S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: A “sheath” fluid passing through a microfluidic channel at low Reynolds number can be directed around another “core” stream and used to dictate the shape as well as the diameter of a core stream.Grooves in the top and bottom of a microfluidic channel were designed to direct the sheath fluid and shape the core fluid.By matching the viscosity and hydrophilicity of the sheath and core fluids, the interfacial effects are minimized and complex fluid shapes can be formed.Controlling the relative flow rates of the sheath and core fluids determines the cross-sectional area of the core fluid.Fibers have been produced with sizes ranging from 300 nm to ~1 mm, and fiber cross-sections can be round, flat, square, or complex as in the case with double anchor fibers. Polymerization of the core fluid downstream from the shaping region solidifies the fibers.Photoinitiated click chemistries are well suited for rapid polymerization of the core fluid by irradiation with ultraviolet light.Fibers with a wide variety of shapes have been produced from a list of polymers including liquid crystals, poly(methylmethacrylate), thiol-ene and thiol-yne resins, polyethylene glycol, and hydrogel derivatives. Minimal shear during the shaping process and mild polymerization conditions also makes the fabrication process well suited for encapsulation of cells and other biological components.
Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
Creators: name: McNeill, Robert S.
name: White, Kristen K.
name: Bash, Ryan E.
name: Constance, Brian H.
name: Vitucci, Mark
name: Miller, C. Ryan
name: Schmid, Ralf S.
name: Huff, Byron
name: Werneke, Andrea M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Current astrocytoma models are limited in their ability to define the roles of oncogenic mutations in specific brain cell types during disease pathogenesis and their utility for preclinical drug development. In order to design a better model system for these applications, phenotypically wild-type cortical astrocytes and neural stem cells (NSC) from conditional, genetically engineered mice (GEM) that harbor various combinations of floxed oncogenic alleles were harvested and grown in culture. Genetic recombination was induced in vitro using adenoviral Cre-mediated recombination, resulting in expression of mutated oncogenes and deletion of tumor suppressor genes. The phenotypic consequences of these mutations were defined by measuring proliferation, transformation, and drug response in vitro. Orthotopic allograft models, whereby transformed cells are stereotactically injected into the brains of immune-competent, syngeneic littermates, were developed to define the role of oncogenic mutations and cell type on tumorigenesis in vivo. Unlike most established human glioblastoma cell line xenografts, injection of transformed GEM-derived cortical astrocytes into the brains of immune-competent littermates produced astrocytomas, including the most aggressive subtype, glioblastoma, that recapitulated the histopathological hallmarks of human astrocytomas, including diffuse invasion of normal brain parenchyma. Bioluminescence imaging of orthotopic allografts from transformed astrocytes engineered to express luciferase was utilized to monitor in vivo tumor growth over time. Thus, astrocytoma models using astrocytes and NSC harvested from GEM with conditional oncogenic alleles provide an integrated system to study the genetics and cell biology of astrocytoma pathogenesis in vitro and in vivo and may be useful in preclinical drug development for these devastating diseases.
Fat to Muscle Ratio Measurements with Dual Energy X Ray Absorbtiometry
Creators: name: Chen, A.
name: Wang, A.
name: Broadbent, C.
name: Zhong, J.
name: Dilmanian, A.
name: Zafonte, F.
name: Zhong, Z.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Medical Physics (physics.med-ph)
subject: FOS: Physical sciences

description: Accurate measurement of the fat-to-muscle ratio in animal model is important for obesity research. An efficient way to measure the fat to muscle ratio in animal model using dual-energy absorptiometry is presented in this paper. A radioactive source exciting x-ray fluorescence from a target material is used to provide the two x-ray energies needed. The x-rays, after transmitting through the sample, are measured with an energy-sensitive Ge detector. Phantoms and specimens were measured. The results showed that the method was sensitive to the fat to muscle ratios with good linearity. A standard deviation of a few percent in the fat to muscle ratio could be observed with the x-ray dose of 0.001 mGy.
description: 17 pages, 7 figures, Nuclear Instrument Method in Physics Research, 2014
L’effetto della pressione e della temperatura sul (dis)comfort percepito nella human artefact interaction
Creators: name: Califano, Rosaria
Publisher: name: Universita degli studi di Salerno
Year: 2018
Subjects: subject: ING-IND/15 DISEGNO E METODI DELL'INGEGNERIA INDUSTRIALE
subject: Comfort
subject: Temperatura
subject: Pressione

description: 2015 - 2016
description: The aim of this PhD work is to provide indications on comfort in the case of the Man-Machine interface and to guarantee all the tools for evaluating them. In order to analyze comfort, it was necessary to carry out a bibliographic survey on ergonomics and subsequently on comfort, identifying the shortcomings and all the aspects not considered. After these studies, a model of comfort perception was created that summarizes the concept that comfort and discomfort are the measure of the degree of appreciation linked to expectations and to the interaction between the person and the environment. Since comfort and discomfort related to the sitting are widely studied in the automotive field, the model of comfort perception has been applied to this case, identifying all the elements of the model that participate in the comfort / discomfort experiences. The expectation factor was also analyzed, in order to understand the mechanism of the influence of the expectation on general comfort; to prove it, an experimental test was carried out using the "placebo" effect. In the final phase of the discussion, attention was focused on two aspects that influence comfort in the Man-Object interaction, that is, the temperature and the pressure distribution at the interface. For both factors (temperature and pressure) we started from a deep bibliographic research in order to identify the most significant variables, extrapolated from pressure distributions and the temperature of the skin to the body-object interface, which must be considered when wants to evaluate how pressure and temperature at the interface affect perceived comfort. Subsequently, through case studies it was possible to verify all the significant correlations that these variables have with the level of perceived comfort by the subjects who participated in the tests. [edited by Author]
Protein Isolation from the Developing Embryonic Mouse Heart Valve Region
Creators: name: Dyer, Laura A.
name: Wu, Yaxu
name: Patterson, Cam
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Western blot analysis is a commonly employed technique for detecting and quantifying protein levels. However, for small tissue samples, this analysis method may not be sufficiently sensitive to detect a protein of interest. To overcome these difficulties, we examined protocols for obtaining protein from adult human cardiac valves and modified these protocols for the developing early embryonic mouse counterparts. In brief, the mouse embryonic aortic valve regions, including the aortic valve and surrounding aortic wall, are collected in the minimal possible volume of a Tris-based lysis buffer with protease inhibitors. If required based on the breeding strategy, embryos are genotyped prior to pooling four embryonic aortic valve regions for homogenization. After homogenization, an SDS-based sample buffer is used to denature the sample for running on an SDS-PAGE gel and subsequent western blot analysis. Although the protein concentration remains too low to quantify using spectrophotometric protein quantification assays and have sample remaining for subsequent analyses, this technique can be used to successfully detect and semi-quantify phosphorylated proteins via western blot from pooled samples of four embryonic day 13.5 mouse aortic valve regions, each of which yields approximately 1 µg of protein. This technique will be of benefit for studying cell signaling pathway activation and protein expression levels during early embryonic mouse valve development.
Searches for Lepton Flavor Violation in Tau Decays at Belle II
Creators: name: Banerjee, Swagato
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Searches for lepton flavor violation in tau decays are unambiguous signatures of new physics. The branching ratios of tau leptons at the level of 10^-10 - 10^-9 can be probed with 50 ab^-1 of electron-positron annihilation data being collected by the Belle II experiment at the world's highest luminosity accelerator, the SuperKEKB, located at the High Energy Accelerator Research Organization, KEK, in Tsukuba, Japan. Searches with such expected sensitivity will either discover new physics or strongly constrain several new physics models.
description: 24 pages, 8 figures
Uniformly convex metric spaces
Creators: name: Kell, Martin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Metric Geometry (math.MG)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: In this paper the theory of uniformly convex metric spaces is developed. These spaces exhibit a generalized convexity of the metric from a fixed point. Using a (nearly) uniform convexity property a simple proof of reflexivity is presented and a weak topology of such spaces is analyzed. This topology called co-convex topology agrees with the usualy weak topology in Banach spaces. An example of a $CAT(0)$-spaces with weak topology which is not Hausdorff is given. This answers questions raised by Monod 2006, Kirk and Panyanak 2008 and Espínola and Fernández-León 2009. In the end existence and uniqueness of generalized barycenters is shown and a Banach-Saks property is proved.
description: 23 pages
Additional file 1 of Evaluating methodological approaches to assess the severity of infection with SARS-CoV-2 variants: scoping review and applications on Belgian COVID-19 data
Creators: name: Meurisse, Marjan
name: Van Oyen, Herman
name: Blot, Koen
name: Catteau, Lucy
name: Serrien, Ben
name: Klamer, Sofieke
name: Cauët, Emilie
name: Robert, Annie
name: Van Goethem, Nina
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1: Figure S1. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram, presenting the selection process of articles included in the scoping literature review, conducted to summarize methodological approaches to study the severity of SARS-CoV-2 variants using observational data and identify limitations and potential biases resulting from the study design, data analysis approach, underlying surveillance strategies, or data infrastructure.