cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Design of Dynamics Invariant LSTM for Touch Based Human-UAV Interaction Detection
Creators: name: Peringal, Anees
name: Chehadeh, Mohamad
name: Azzam, Rana
name: Hamandi, Mahmoud
name: Boiko, Igor
name: Zweiri, Yahya
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The field of Unmanned Aerial Vehicles (UAVs) has reached a high level of maturity in the last few years. Hence, bringing such platforms from closed labs, to day-to-day interactions with humans is important for commercialization of UAVs. One particular human-UAV scenario of interest for this paper is the payload handover scheme, where a UAV hands over a payload to a human upon their request. In this scope, this paper presents a novel real-time human-UAV interaction detection approach, where Long short-term memory (LSTM) based neural network is developed to detect state profiles resulting from human interaction dynamics. A novel data pre-processing technique is presented; this technique leverages estimated process parameters of training and testing UAVs to build dynamics invariant testing data. The proposed detection algorithm is lightweight and thus can be deployed in real-time using off the shelf UAV platforms; in addition, it depends solely on inertial and position measurements present on any classical UAV platform. The proposed approach is demonstrated on a payload handover task between multirotor UAVs and humans. Training and testing data were collected using real-time experiments. The detection approach has achieved an accuracy of 96\%, giving no false positives even in the presence of external wind disturbances, and when deployed and tested on two different UAVs.
description: 13 pages, 13 figures, submitted to IEEE access, A supplementary video for the work presented in this paper can be accessed from https://youtu.be/29N_OXBl1mc
Response of Coastal Fishes to the Gulf of Mexico Oil Disaster
Creators: name: Heck, Kenneth L.
name: Fodrie, F. Joel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: The ecosystem-level impacts of the Deepwater Horizon disaster have been largely unpredictable due to the unique setting and magnitude of this spill. We used a five-year (2006–2010) data set within the oil-affected region to explore acute consequences for early-stage survival of fish species inhabiting seagrass nursery habitat. Although many of these species spawned during spring-summer, and produced larvae vulnerable to oil-polluted water, overall and species-by-species catch rates were high in 2010 after the spill (1,989±220 fishes km-towed−1 [μ ± 1SE]) relative to the previous four years (1,080±43 fishes km-towed−1). Also, several exploited species were characterized by notably higher juvenile catch rates during 2010 following large-scale fisheries closures in the northern Gulf, although overall statistical results for the effects of fishery closures on assemblage-wide CPUE data were ambiguous. We conclude that immediate, catastrophic losses of 2010 cohorts were largely avoided, and that no shifts in species composition occurred following the spill. The potential long-term impacts facing fishes as a result of chronic exposure and delayed, indirect effects now require attention.
CFO Outlook Survey: 2nd Quarter 2002
Creators: name: Financial Executives Institute (FEI)
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Gross domestic product growth (1); optimism toward economy (1); changes in company earnings, spending, and employees (11); company recovery from recession (1); stock returns (6); misleading financial reporting (1); aggressiveness of auditor (2); whistle-blower protection procedures (1); agreement with various statements (5).
A numerical study of stellar discs in galactic nuclei
Creators: name: Panamarev, Taras
name: Kocsis, Bence
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We explore the dynamics of stellar discs in the close vicinity of a supermassive black hole (SMBH) by means of direct $N$-body simulations. We show that an isolated nuclear stellar disc exhibits anisotropic mass segregation meaning that massive stars settle to lower orbital inclinations and more circular orbits than the light stars. However, in systems in which the stellar disc is embedded in a much more massive isotropic stellar cluster, anisotropic mass segregation tends to be suppressed. In both cases, an initially thin stellar disc becomes thicker, especially in the inner parts due to the fluctuating anisotropy in the spherical component. We find that vector resonant relaxation is quenched in the disc by nodal precession, but it is still the most efficient relaxation process around SMBHs of mass $10^6M_\odot$ and above. Two body relaxation may dominate for less massive SMBHs found in dwarf galaxies. Stellar discs embedded in massive isotropic stellar clusters ultimately tend to become isotropic on the local two-body relaxation time-scale. Our simulations show that the dynamics of young stars at the centre of the Milky Way is mostly driven by vector resonant relaxation leading to an anticorrelation between the scatter of orbital inclinations and distance from the SMBH. If the $S$-stars formed in a disc less than 10 Myr ago, they may coexist with a cusp of stellar mass black holes or an intermediate mass black hole with mass up to $1000M_\odot$ to reproduce the observed scatter of angular momenta.
description: 22 pages, 23 figures, accepted by MNRAS
Fannie Mae National Housing Survey Monthly Key Indicators--June, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite
Creators: name: Murphy, Paul
name: Baker, David
name: Koga, Nobuyasu
name: Strauch, Eva-Maria
name: Corn, Jacob E.
name: Richter, Florian
name: Meiler, Jens
name: Fleishman, Sarel J.
name: Khare, Sagar D.
name: Lemmon, Gordon
name: Leaver-Fay, Andrew
name: Ashworth, Justin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Macromolecular modeling and design are increasingly useful in basic research, biotechnology, and teaching. However, the absence of a user-friendly modeling framework that provides access to a wide range of modeling capabilities is hampering the wider adoption of computational methods by non-experts. RosettaScripts is an XML-like language for specifying modeling tasks in the Rosetta framework. RosettaScripts provides access to protocol-level functionalities, such as rigid-body docking and sequence redesign, and allows fast testing and deployment of complex protocols without need for modifying or recompiling the underlying C++ code. We illustrate these capabilities with RosettaScripts protocols for the stabilization of proteins, the generation of computationally constrained libraries for experimental selection of higher-affinity binding proteins, loop remodeling, small-molecule ligand docking, design of ligand-binding proteins, and specificity redesign in DNA-binding proteins.
Nonlinear behavior and mode coupling in spin transfer nano-oscillators
Creators: name: Lebrun, Romain
name: Locatelli, Nicolas
name: Araujo, Flavio Abreu
name: Kubota, Hitoshi
name: Tsunegi, Sumito
name: Yakushiji, Kay
name: Fukushima, Akio
name: Grollier, Julie
name: Yuasa, Shinji
name: Cros, Vincent
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: By investigating thoroughly the tunable behavior of coupled modes, we highlight how it provides new means to handle the properties of spin transfer nano-oscillators. We first demonstrate that the main features of the microwave signal associated with coupled vortex dynamics i.e. frequency, spectral coherence, critical current, mode localization, depends drastically on the relative vortex core polarities. Secondly we report a large reduction of the nonlinear linewidth broadening obtained by changing the effective damping through the control of the core configuration. Such a level of control on the nonlinear behavior reinforces our choice to exploit the microwave properties of collective modes for applications of spintronic devices in novel generation of integrated telecommunication devices.
Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML
Creators: name: Ramdeo, Ritu
name: Agarwal, Mukesh K.
name: Agarwal, Munna L.
name: Roth, Bryan L.
name: Chakrabarti, Amitabha
name: Wald, David N.
name: Rana, Sonia
name: Tse, William
name: Gupta, Kalpana
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: As the defining feature of Acute Myeloid Leukemia (AML) is a maturation arrest, a highly desirable therapeutic strategy is to induce leukemic cell maturation. This therapeutic strategy has the potential of avoiding the significant side effects that occur with the traditional AML therapeutics. We identified a natural compound securinine, as a leukemia differentiation-inducing agent. Securinine is a plant-derived alkaloid that has previously been used clinically as a therapeutic for primarily neurological related diseases. Securinine induces monocytic differentiation of a wide range of myeloid leukemia cell lines as well as primary leukemic patient samples. Securinine's clinical potential for AML can be seen from its ability to induce significant growth arrest in cell lines and patient samples as well as its activity in significantly impairing the growth of AML tumors in nude mice. In addition, securinine can synergize with currently employed agents such as ATRA and decitabine to induce differentiation. This study has revealed securinine induces differentiation through the activation of DNA damage signaling. Securinine is a promising new monocytic differentiation inducing agent for AML that has seen previous clinical use for non-related disorders.
Fannie Mae National Housing Survey Monthly Key Indicators--July, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Terrestrial planet formation in low-mass disks: dependence with initial conditions
Creators: name: Ronco, María Paula
name: de Elía, Gonzalo Carlos
name: Guilera, Octavio Miguel
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: In general, most of the studies of terrestrial-type planet formation typically use ad hoc initial conditions. In this work we improved the initial conditions described in Ronco & de Elía (2014) starting with a semi-analytical model wich simulates the evolution of the protoplanetary disk during the gas phase. The results of the semi-analytical model are then used as initial conditions for the N-body simulations. We show that the planetary systems considered are not sensitive to the particular initial distribution of embryos and planetesimals and thus, the results are globally similar to those found in the previous work.
description: 2 pages, 2 figures - Complex Planetary Systems - IAU Symposium No. 310, 2014
Fannie Mae National Housing Survey Monthly Key Indicators--August, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Oblique propagation of longitudinal waves in magnetized spin-1/2 plasmas: Independent evolution of spin-up and spin-down electrons
Creators: name: Andreev, Pavel A.
name: Kuz'menkov, L. S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: We consider quantum plasmas of electrons and motionless ions. We describe separate evolution of spin-up and spin-down electrons. We present corresponding set of quantum hydrodynamic equations. We assume that plasmas are placed in an uniform external magnetic field. We account different occupation of spin-up and spin-down quantum states in equilibrium degenerate plasmas. This effect is included via equations of state for pressure of each species of electrons. We study oblique propagation of longitudinal waves. We show that instead of two well-known waves (the Langmuir wave and the Trivelpiece--Gould wave), plasmas reveal four wave solutions. New solutions exist due to both the separate consideration of spin-up and spin-down electrons \textit{and} different occupation of spin-up and spin-down quantum states in equilibrium state of degenerate plasmas.
description: 8 pages, 9 figures
Design and Implementation of the Illinois Express Quantum Metropolitan Area Network
Creators: name: Chung, Joaquin
name: Eastman, Ely M.
name: Kanter, Gregory S.
name: Kapoor, Keshav
name: Lauk, Nikolai
name: Peña, Cristián
name: Plunkett, Robert
name: Sinclair, Neil
name: Thomas, Jordan M.
name: Valivarthi, Raju
name: Xie, Si
name: Kettimuthu, Rajkumar
name: Kumar, Prem
name: Spentzouris, Panagiotis
name: Spiropulu, Maria
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Illinois Express Quantum Network (IEQNET) is a program to realize metropolitan scale quantum networking over deployed optical fiber using currently available technology. IEQNET consists of multiple sites that are geographically dispersed in the Chicago metropolitan area. Each site has one or more quantum nodes (Q-nodes) representing the communication parties in a quantum network. Q-nodes generate or measure quantum signals such as entangled photons and communicate the measurement results via standard, classical signals and conventional networking processes. The entangled photons in IEQNET nodes are generated at multiple wavelengths, and are selectively distributed to the desired users via transparent optical switches. Here we describe the network architecture of IEQNET, including the Internet-inspired layered hierarchy that leverages software-defined networking (SDN) technology to perform traditional wavelength routing and assignment between the Q-nodes. Specifically, SDN decouples the control and data planes, with the control plane being entirely implemented in the classical domain. We also discuss the IEQNET processes that address issues associated with synchronization, calibration, network monitoring, and scheduling. An important goal of IEQNET is to demonstrate the extent to which the control plane classical signals can co-propagate with the data plane quantum signals in the same fiber lines (quantum-classical signal "coexistence"). This goal is furthered by the use of tunable narrow-band optical filtering at the receivers and, at least in some cases, a wide wavelength separation between the quantum and classical channels. We envision IEQNET to aid in developing robust and practical quantum networks by demonstrating metro-scale quantum communication tasks such as entanglement distribution and quantum-state teleportation.
description: 20 pages, 11 figures. arXiv admin note: text overlap with arXiv:2111.10256
SERCA2 Regulates Non-CF and CF Airway Epithelial Cell Response to Ozone
Creators: name: Nichols, David P.
name: White, Carl W.
name: Rancourt, Raymond C.
name: Ahmad, Aftab
name: Ahmad, Shama
name: Randell, Scott H.
name: Strand, Matthew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Calcium mobilization can regulate a wide range of essential functions of respiratory epithelium, including ion transport, ciliary beat frequency, and secretion of mucus, all of which are modified in cystic fibrosis (CF). SERCA2, an important controller of calcium signaling, is deficient in CF epithelium. We conducted this study to determine whether SERCA2 deficiency can modulate airway epithelial responses to environmental oxidants such as ozone. This could contribute to the pathogenesis of pulmonary exacerbations, which are important and frequent clinical events in CF. To address this, we used air-liquid interface (ALI) cultures of non-CF and CF cell lines, as well as differentiated cultures of cells derived from non-CF and CF patients. We found that ozone exposure caused enhanced membrane damage, mitochondrial dysfunction and apoptotic cell death in CF airway epithelial cell lines relative to non-CF. Ozone exposure caused increased proinflammatory cytokine production in CF airway epithelial cell lines. Elevated proinflammatory cytokine production also was observed in shRNA-mediated SERCA2 knockdown cells. Overexpression of SERCA2 reversed ozone-induced proinflammatory cytokine production. Ozone-induced proinflammatory cytokine production was NF-κB- dependent. In a stable NF-κB reporter cell line, SERCA2 inhibition and knockdown both upregulated cytomix-induced NF-κB activity, indicating importance of SERCA2 in modulating NF-κB activity. In this system, increased NF-κB activity was also accompanied by increased IL-8 production. Ozone also induced NF-κB activity and IL-8 release, an effect that was greater in SERCA2-silenced NF-κB-reporter cells. SERCA2 overexpression reversed cytomix-induced increased IL-8 release and total nuclear p65 in CFTR-deficient (16HBE-AS) cells. These studies suggest that SERCA2 is an important regulator of the proinflammatory response of airway epithelial cells and could be a potential therapeutic target.
Late-time cosmology with phantom dark-energy in $f(Q)$ gravity
Creators: name: Lymperis, Andreas
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Motivated by the exciting features and a recent proposed general form of the function of non-metricity scalar Q, we investigate the cosmological implications in $f(Q)$ gravity, through the resulting effective dark energy sector, extracting analytical expressions for the dark energy density, equation-of-state parameter and the deceleration parameters. We show that even in the absence of a cosmological constant, the universe exhibits the usual thermal history, with the sequence of matter and dark energy eras, and the dark-energy equation-of-state parameter always lie in the phantom regime. Additionally, calculating the age of the universe, through the extracted analytical equations of the scenario at hand, we show that the result coincide with the value corresponding to $Λ$CDM scenario within 1$σ$. Moreover, we show the excellent agreement of the scenario at hand with Supernovae type Ia observational data. Lastly, comparing the cosmological behavior in the case of the absence of an explicit cosmological constant, with the one of the presence of a cosmological constant we show that $f(Q)$ gravity can mimic the cosmological constant in a very efficient way, providing very similar behavior, revealing the advantages and capabilitites of the scenario at hand.
description: 18 pages, 5 figures
Invariant scrambled sets, uniform rigidity and weak mixing
Creators: name: Foryś, Magdalena
name: Huang, Wen
name: Li, Jian
name: Oprocha, Piotr
Publisher: name: arXiv
Year: 2014
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 54H20, 37B05, 37B20

description: We show that for a non-trivial transitive dynamical system, it has a dense Mycielski invariant strongly scrambled set if and only if it has a fixed point, and it has a dense Mycielski invariant $δ$-scrambled set for some $δ>0$ if and only if it has a fixed point and not uniformly rigid. We also provide two methods for the construction of completely scrambled systems which are weakly mixing, proximal and uniformly rigid.
description: 17 pages, to appear in Israel Journal of Mathematics
Stability of Yellow Fever Virus under Recombinatory Pressure as Compared with Chikungunya Virus
Creators: name: Lang, Jean
name: Higgs, Stephen
name: McGee, Charles E.
name: Guy, Bruno
name: Tsetsarkin, Konstantin A.
name: Plante, Kenneth
name: Vanlandingham, Dana L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Recombination is a mechanism whereby positive sense single stranded RNA viruses exchange segments of genetic information. Recent phylogenetic analyses of naturally occurring recombinant flaviviruses have raised concerns regarding the potential for the emergence of virulent recombinants either post-vaccination or following co-infection with two distinct wild-type viruses. To characterize the conditions and sequences that favor RNA arthropod-borne virus recombination we constructed yellow fever virus (YFV) 17D recombinant crosses containing complementary deletions in the envelope protein coding sequence. These constructs were designed to strongly favor recombination, and the detection conditions were optimized to achieve high sensitivity recovery of putative recombinants. Full length recombinant YFV 17D virus was never detected under any of the experimental conditions examined, despite achieving estimated YFV replicon co-infection levels of ∼2.4×106 in BHK-21 (vertebrate) cells and ∼1.05×105 in C710 (arthropod) cells. Additionally YFV 17D superinfection resistance was observed in vertebrate and arthropod cells harboring a primary infection with wild-type YFV Asibi strain. Furthermore recombination potential was also evaluated using similarly designed chikungunya virus (CHIKV) replicons towards validation of this strategy for recombination detection. Non-homologus recombination was observed for CHIKV within the structural gene coding sequence resulting in an in-frame duplication of capsid and E3 gene. Based on these data, it is concluded that even in the unlikely event of a high level acute co-infection of two distinct YFV genomes in an arthropod or vertebrate host, the generation of viable flavivirus recombinants is extremely unlikely.
title: Direct Elicitation of Parametric Belief Distributions: An application to inflation expectations
Creators: name: Gonzalez-Fernandez, Pedro
name: Bosch-Rosa, Ciril
name: Meissner, Thomas
Publisher: name: Hertie School
Year: 2024

description: We introduce a novel method to elicit belief distributions and apply it to elicit inflation expectations in a representative US sample through a pre-registered survey experiment. Our approach elicits beta belief distributions directly in a two-step process. First, participants specify their minimum and maximum expected inflation. They then use a graphical interface with two sliders to adjust the mean and variance of their inflation belief distribution. We benchmark our method against the “Bins” method, popularized by the New York Fed’s Survey of Consumer Expectations (SCE). Our findings reveal significant variations in elicited belief distributions depending on the method used. Specifically, our approach yields higher mean inflation estimates and substantially reduces the standard deviations of the distributions. Respondents report that our method is easier to use, more engaging, and better allows them to express their beliefs. Furthermore, the resulting distributions more accurately reflect participants’ beliefs across several dimensions and show stronger correlations with their point predictions.
description: Berlin School of Economics Discussion Papers; 48
Observation of the Uller-Zenneck wave
Creators: name: Faryad, Muhammad
name: Lakhtakia, Akhlesh
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The Uller-Zenneck wave has been theoretically predicted to exist at the planar interface of two homogeneous dielectric materials of which only one must be dissipative. Experimental confirmation of this century-old prediction was obtained experimentally by exciting the Uller-Zenneck wave as a Floquet harmonic of non-zero order at the periodically corrugated interface of air and crystalline silicon in the 400-to-900-nm spectral regime. Application for intra-chip optical interconnects at ~850 nm appears promising.
Phonetics and Phonology Between Theory and Practice: A Study of English Major Students in Saudi Arabia
Creators: name: Almoayidi, Khedir
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: In Saudi Arabia, an important rationale for the inclusion of phonetics and phonology in university degree courses for aspiring English language teachers is to improve their proficiency in second language pronunciation. This, in turn, contributes to their overall ability to use the language effectively in international communicative encounters. Many English major students in Saudi Arabia are aware of the basic terminology and theoretical underpinnings of the study of phonetics and phonology with specific reference to English at the completion of their degree. It has been noted, however, that they are often unable to apply this knowledge to improve their pronunciation. This practical problem was the motivation for undertaking the current study. Using a mixed methods design, the present study set out to trial an innovative approach to the teaching of phonetics and phonology in the Saudi university context. Specifically, the emphasis was placed on enabling learners to apply their knowledge to optimise their pronunciation achievement. Thirty-two English major undergraduate students in Saudi Arabian university who were preparing to become English language teachers were divided in two equal-size groups: a control group comprising students enrolled in the standard phonetics and phonology course at their university; and an experimental group comprising students exposed (over the same period) to a series of practice-based classes which focused on the application of phonetics and phonological principles and concepts through structured reception and production activities. These data were complemented by interviews with phonetics and phonology course instructors and practicing English language teachers. The oral production tests completed by the student participants in both groups were rated by independent native speakers of Australian English. Results revealed that the participants who completed the experimental practice-based course improved significantly in their production of English words containing sounds that do not exist in the Arabic language system. Their production was also rated as less accented than that of the control group participants. Data obtained from the interviews highlighted the general lack of confidence among the participants in regard to their own English pronunciation, and in their ability to teach pronunciation in their future careers. The participants expressed a general desire for more opportunities to practise speaking in English and responded well to such activities in the experimental course. The findings of this study suggest that measurable gains in pronunciation performance can be obtained through a one-semester course. This has important pedagogical implications for the way in which English language teachers are trained in the Saudi university context.
Spectral optical monitoring of the double peaked emission line AGN Arp 102B: II. Variability of the broad line properties
Creators: name: Popovic, L. C.
name: Shapovalova, A. I.
name: Ilic, D.
name: Burenkov, A. N.
name: Chavushyan, V. H.
name: Kollatschny, W.
name: Kovacevic, A.
name: Valdes, J. R.
name: Leon-Tavares, J.
name: Bochkarev, N. G.
name: Patino-Alvarez, V.
name: Torrealba, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate a long-term (26 years, from 1987 to 2013) variability in the broad spectral line properties of the radio galaxy Arp 102B, an active galaxy with broad double-peaked emission lines. We use observations presented in Paper I (Shapovalova et al. 2013) in the period from 1987 to 2011, and a new set of observations performed in 2012--2013. To explore the BLR geometry, and clarify some contradictions about the nature of the BLR in Arp 102B we explore variations in the H$α$ and H$β$ line parameters during the monitored period. We fit the broad lines with three broad Gaussian functions finding the positions and intensities of the blue and red peaks in H$α$ and H$β$. Additionally we fit averaged line profiles with the disc model. We find that the broad line profiles are double-peaked and have not been changed significantly in shapes, beside an additional small peak that, from time to time can be seen in the blue part of the H$α$ line. The positions of the blue and red peaks { have not changed significantly during the monitored period. The H$β$ line is broader than H$α$ line in the monitored period. The disc model is able to reproduce the H$β$ and H$α$ broad line profiles, however, observed variability in the line parameters are not in a good agreement with the emission disc hypothesis. It seems that the BLR of Arp 102B has a disc-like geometry, but the role of an outflow can also play an important role in observed variation of the broad line properties.
description: 17 pages, Accepted for publication in A&A
Stabilization of Nrf2 Protein by D3T Provides Protection against Ethanol-Induced Apoptosis in PC12 Cells
Creators: name: Chen, Shao-yu
name: Yan, Dong
name: Dong, Jian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Previous studies have demonstrated that maternal ethanol exposure induces a moderate increase in Nrf2 protein expression in mouse embryos. Pretreatment with the Nrf2 inducer, 3H-1, 2-dithiole-3-thione (D3T), significantly increases the Nrf2 protein levels and prevents apoptosis in ethanol-exposed embryos. The present study, using PC12 cells, was designed to determine whether increased Nrf2 stability is a mechanism by which D3T enhances Nrf2 activation and subsequent antioxidant protection. Ethanol and D3T treatment resulted in a significant accumulation of Nrf2 protein in PC 12 cells. CHX chase analysis has shown that ethanol treatment delayed the degradation of Nrf2 protein in PC12 cells. A significantly greater decrease in Nrf2 protein degradation was observed in the cells treated with D3T alone or with both ethanol and D3T. In addition, D3T treatment significantly reduced ethanol-induced apoptosis. These results demonstrate that the stabilization of Nrf2 protein by D3T confers protection against ethanol-induced apoptosis.
Magnetoresistance of disordered graphene: from low to high temperatures
Creators: name: Jabakhanji, B.
name: Kazazis, D.
name: Desrat, W.
name: Michon, A.
name: Portail, M.
name: Jouault, B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present the magnetoresistance (MR) of highly doped monolayer graphene layers grown by chemical vapor deposition on 6H-SiC. The magnetotransport studies are performed on a large temperature range, from $T$ = 1.7 K up to room temperature. The MR exhibits a maximum in the temperature range $120-240$ K. The maximum is observed at intermediate magnetic fields ($B=2-6$ T), in between the weak localization and the Shubnikov-de Haas regimes. It results from the competition of two mechanisms. First, the low field magnetoresistance increases continuously with $T$ and has a purely classical origin. This positive MR is induced by thermal averaging and finds its physical origin in the energy dependence of the mobility around the Fermi energy. Second, the high field negative MR originates from the electron-electron interaction (EEI). The transition from the diffusive to the ballistic regime is observed. The amplitude of the EEI correction points towards the coexistence of both long and short range disorder in these samples.
Fannie Mae National Housing Survey Monthly Key Indicators--September, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Structural Asymmetry of Phosphodiesterase-9, Potential Protonation of a Glutamic Acid, and Role of the Invariant Glutamine
Creators: name: Hou, Jing
name: Xu, Jie
name: Luo, Hai-Bin
name: Zhao, Ruizhi
name: Liu, Ming
name: Ke, Hengming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: PDE9 inhibitors show potential for treatment of diseases such as diabetes. To help with discovery of PDE9 inhibitors, we performed mutagenesis, kinetic, crystallographic, and molecular dynamics analyses on the active site residues of Gln453 and its stabilizing partner Glu406. The crystal structures of the PDE9 Q453E mutant (PDE9Q453E) in complex with inhibitors IBMX and (S)-BAY73-6691 showed asymmetric binding of the inhibitors in two subunits of the PDE9Q453E dimer and also the significant positional change of the M-loop at the active site. The kinetic analysis of the Q453E and E406A mutants suggested that the invariant glutamine is critical for binding of substrates and inhibitors, but is unlikely to play a key role in the differentiation between substrates of cGMP and cAMP. The molecular dynamics simulations suggest that residue Glu406 may be protonated and may thus explain the hydrogen bond distance between two side chain oxygens of Glu453 and Glu406 in the crystal structure of the PDE9Q453E mutant. The information from these studies may be useful for design of PDE9 inhibitors.
Determining doping efficiency and mobility from conductivity and Seebeck data of n-doped C60 layers
Creators: name: Menke, Torben
name: Ray, Debdutta
name: Kleemann, Hans
name: Leo, Karl
name: Riede, Moritz
Publisher: name: arXiv
Year: 2014
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: In this work, we introduce models for deriving lower limits for the key parameters doping efficiency, charge carrier concentration, and charge carrier mobility from conductivity data of doped organic semiconductors. The models are applied to data of thin layers of Fullerene C60 n-doped by four different n-dopants. Combining these findings with thermoelectric Seebeck data, the energetic position of the transport level can be narrowed down and trends for the absolute values are derived.
Structural Mechanism of S-Adenosyl Methionine Binding to Catechol O-Methyltransferase
Creators: name: Diatchenko, Luda
name: Tsao, Douglas
name: Dokholyan, Nikolay V.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Methyltransferases possess a homologous domain that requires both a divalent metal cation and S-adenosyl-L-methionine (SAM) to catalyze its reactions. The kinetics of several methyltransferases has been well characterized; however, the details regarding their structural mechanisms have remained unclear to date. Using catechol O-methyltransferase (COMT) as a model, we perform discrete molecular dynamics and computational docking simulations to elucidate the initial stages of cofactor binding. We find that COMT binds SAM via an induced-fit mechanism, where SAM adopts a different docking pose in the absence of metal and substrate in comparison to the holoenzyme. Flexible modeling of the active site side-chains is essential for observing the lowest energy state in the apoenzyme; rigid docking tools are unable to recapitulate the pose unless the appropriate side-chain conformations are given a priori. From our docking results, we hypothesize that the metal reorients SAM in a conformation suitable for donating its methyl substituent to the recipient ligand. The proposed mechanism enables a general understanding of how divalent metal cations contribute to methyltransferase function.
A Hardware-based HEFT Scheduler Implementation for Dynamic Workloads on Heterogeneous SoCs
Creators: name: Fusco, Alexander
name: Hassan, Sahil
name: Mack, Joshua
name: Akoglu, Ali
Publisher: name: arXiv
Year: 2022
Subjects: subject: Hardware Architecture (cs.AR)
subject: Performance (cs.PF)
subject: FOS: Computer and information sciences

description: Non-uniform performance and power consumption across the processing elements (PEs) of heterogeneous SoCs increase the computation complexity of the task scheduling problem compared to homogeneous architectures. Latency of a software-based scheduler with the increased heterogeneity level in terms of number and types of PEs creates the necessity of deploying a scheduler as an overlay processor in hardware to be able to make scheduling decisions rapidly and enable deployment of real-life applications on heterogeneous SoCs. In this study we present the design trade-offs involved for implementing and deploying the runtime variant of the heterogeneous earliest finish time algorithm (HEFT_RT) on the FPGA. We conduct performance evaluations on a SoC configuration emulated over the Xilinx Zynq ZCU102 platform. In a runtime environment we demonstrate hardware-based HEFT_RT's ability to make scheduling decisions with 9.144 ns latency on average, process 26.7% more tasks per second compared to its software counterpart, and reduce the scheduling latency by up to a factor of 183x based on workloads composed of mixture of dynamically arriving real-life signal processing applications.
description: Presented at 2022 IFIP/IEEE 30th International Conference on Very Large Scale Integration (October 3-5)
Optimization of the Shape of a Hydrokinetic Turbine's Draft Tube and Hub Assembly Using Design-by-Morphing with Bayesian Optimization
Creators: name: Sheikh, Haris Moazam
name: Callan, Tess A.
name: Hennessy, Kealan J.
name: Marcus, Philip S.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computational Geometry (cs.CG)
subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Machine Learning (cs.LG)
subject: Geometric Topology (math.GT)
subject: Computation (stat.CO)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Finding the optimal design of a hydrodynamic or aerodynamic surface is often impossible due to the expense of evaluating the cost functions (say, with computational fluid dynamics) needed to determine the performances of the flows that the surface controls. In addition, inherent limitations of the design space itself due to imposed geometric constraints, conventional parameterization methods, and user bias can restrict {\it all} of the designs within a chosen design space regardless of whether traditional optimization methods or newer, data-driven design algorithms with machine learning are used to search the design space. We present a 2-pronged attack to address these difficulties: we propose (1) a methodology to create the design space using morphing that we call {\it Design-by-Morphing} (DbM); and (2) an optimization algorithm to search that space that uses a novel Bayesian Optimization (BO) strategy that we call {\it Mixed variable, Multi-Objective Bayesian Optimization} (MixMOBO). We apply this shape optimization strategy to maximize the power output of a hydrokinetic turbine. Applying these two strategies in tandem, we demonstrate that we can create a novel, geometrically-unconstrained, design space of a draft tube and hub shape and then optimize them simultaneously with a {\it minimum} number of cost function calls. Our framework is versatile and can be applied to the shape optimization of a variety of fluid problems.
Fannie Mae National Housing Survey Monthly Key Indicators--October, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Inverse cascades of kinetic energy and thermal variance in three-dimensional horizontally extended turbulent convection
Creators: name: Vieweg, Philipp P.
name: Scheel, Janet D.
name: Stepanov, Rodion
name: Schumacher, Jörg
Publisher: name: arXiv
Year: 2022
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Inverse cascades of kinetic energy and thermal variance in the subset of vertically homogeneous modes in spectral space are found to cause a slow aggregation to a pair of convective supergranules that eventually fill the whole horizontally extended, three-dimensional, turbulent Rayleigh-Bénard convection layer when a heat flux is prescribed at the top and bottom. An additional weak rotation of the layer around the vertical axis stops this aggregation at a scale that is smaller than the lateral domain extension and ceases the inverse cascade for the thermal variance. The inverse cascade for the kinetic energy remains intact, even for times at which the root mean square values of temperature and velocity have reached the statistically steady state. This kinetic energy inverse cascade sustains the horizontally extended convection patterns which are best visible in the temperature field. The resulting characteristic length of the aggregated convection patterns depends on the thermal driving and linearly on the strength of rotation. Our study demonstrates the importance of inverse energy cascades beyond the two-dimensional turbulence case in a three-dimensional convection flow that is subject to a multi-scale energy injection by thermal plumes and driven by boundary heat fluxes as typically present in natural geo- and astrophysical systems, such as solar convection.
description: 15 pages, 10 figures
Purdue Opinion Panel # 63: Youth's Attitudes Toward the Peace Corps, National Security and Education
Creators: name: Panel, The Purdue Opinion
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Respondent's grade in school (1); mother's education (1); Peace Corps (4); what does respondent plan to do after finishing high school (1); what kind of job does respondent expect to have 20 years from now (1); best way to spend $2 billion for national security (1); how many newspapers does respondent's family subscribe to or buy regularly (1); items respondent has in home (1); opinion of certain school subjects (8); what course of study is respondent taking/planning to take in high school (1); what type of college does respondent plan to attend (1); how important will knowledge of "good English" be in job respondent expects to have 20 years from now (1); educational materials used during present school year (1); do/do not speak or read any language other than English (1); most important thing young people should get out of high school (1); important topics in an English course (1); kinds of grades respondent usually gets in high school (2); respondent's final grade in last English class (1); how much time in an average week does respondent spend studying English outside of school (1); spare-time reading (2); how much time does respondent spend reading newspaper each day (1); about how many hours does mother spend reading in an average week (1); about how many hours does father spend reading in an average week (1); how many books does respondent presently own not counting school books (1); about how many books does respondent have in whole home (1); how many different magazines does respondent's family subscribe to or buy regularly (1); one group of people respondent thinks can do the most to promote peace in the world (1); which one film from pairs of certain institutions would prefer to see (36); thing that bothers respondent most about friends (1).
Bioengineering liver microtissues for modeling non-alcoholic fatty liver disease
Creators: name: Aasadollahei, Negar
name: Rezaei, Niloufar
name: Golroo, Reihaneh
name: Agarwal, Tarun
name: Vosough, Massoud
name: Piryaei, Abbas
Publisher: name: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Year: 2023
Subjects: non-alcoholic fatty liver disease
in vitro modeling
bioengineering
liver microtissue
liver organoid
organ-on-a-chip

description: Non-alcoholic fatty liver disease (NAFLD) has become the world’s most common chronic liver disease. However, due to the lack of reliable in vitro NAFLD models, drug development studies have faced many limitations, and there is no food and drug administration-approved medicine for NAFLD treatment. A functional biomimetic in vitro human liver model requires an optimized natural microenvironment using appropriate cellular composition, to provide constructive cell-cell interactions, and niche-specific bio-molecules to supply crucial cues as cell-matrix interplay. Such a suitable liver model could employ appropriate and desired biochemical, mechanical, and physical properties similar to native tissue. Moreover, bioengineered three-dimensional tissues, specially microtissues and organoids, and more recently using infusion-based cultivation systems such as microfluidics can mimic natural tissue conditions and facilitate the exchange of nutrients and soluble factors to improve physiological function in the in vitro generated constructs. This review highlights the key players involved in NAFLD initiation and progression and discussed the available cells and matrices for in vitro NAFLD modeling. The strategies for optimizing the liver microenvironment to generate a powerful and biomimetic in vitro NAFLD model were described as well. Finally, the current challenges and future perospective for promotion in this subject were discussed.
description: EXCLI Journal; 22:Doc367; ISSN 1611-2156