cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Getti impazziti dal buco nero a trottola
Creators: Ufficio stampa Inaf
Publisher: name: Media Inaf
Year: 2019

V404 Cygni, sistema binario formato da una stella e da un buco nero, è particolare a causa di un evidente disallineamento tra il disco di materiale e il buco nero al centro. Quest’ultimo emette lampi di luce improvvisi e intensi, ma è la prima volta, però, che vediamo un getto di materia accelerato da un buco nero cambiare direzione in poche ore. Allo studio pubblicato su Nature ha partecipato anche Tomaso Belloni dell'Inaf di Brera
title: Ð§Ð¸ÑÐ»ÐµÐ½Ð½Ð¾-Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¾Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾Ð´Ñ Ð¾Ð´Ð° Ðº Ð¾Ð±ÐµÐ·Ð²ÐµÑÐ¸Ð²Ð°Ð½Ð¸Ñ Ð¼Ð°Ð½Ð¸Ð¿ÑÐ»ÑÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼ ÐºÐ¾Ð¿Ð¸ÑÑÑÑÐ¸Ð¼Ð¸ Ð¼Ð°Ð½Ð¸Ð¿ÑÐ»ÑÑÐ¾ÑÐ°Ð¼Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ²ÑÑÐ½Ð½Ð¸ÐºÐ¾Ð², ÐÐ¸ÐºÐ¸ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÑÐ¸ÑÑÐµÐ¼Ñ Ð¾Ð±ÐµÐ·Ð²ÐµÑÐ¸Ð²Ð°Ð½Ð¸Ñ
ÐºÐ¾Ð¿Ð¸ÑÑÑÑÐ¸Ð¹ Ð¼Ð°Ð½Ð¸Ð¿ÑÐ»ÑÑÐ¾Ñ
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ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½Ð¾Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
oflload systems
copied manipulator
mathematical model
computer modelling

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¿Ð»Ð°Ð½Ð°ÑÐ½ÑÐ¹, ÑÑÐµÑÐ·Ð²ÐµÐ½Ð½ÑÐ¹ Ð¼Ð°Ð½Ð¸Ð¿ÑÐ»ÑÑÐ¾Ñ, Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð½ÑÐ¹ Ð´Ð»Ñ ÑÐ°Ð±Ð¾ÑÑ Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ ÑÐ»Ð°Ð±Ð¾Ð³Ð¾ Ð³ÑÐ°Ð²Ð¸ÑÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð³Ð¾ Ð²Ð¾Ð·Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ. Ð¦ÐµÐ»Ñ ÑÐ°Ð±Ð¾ÑÑ - Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð° Ðº Ð¾Ð±ÐµÐ·Ð²ÐµÑÐ¸Ð²Ð°Ð½Ð¸Ñ ÐºÐ¾Ð¿Ð¸ÑÑÑÑÐ¸Ð¼Ð¸ Ð¼Ð°Ð½Ð¸Ð¿ÑÐ»ÑÑÐ¾ÑÐ°Ð¼Ð¸ Ð¿ÑÑÑÐ¼ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½ÑÑ Ð¼Ð¾Ð´ÐµÐ»ÐµÐ¹. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð²Ð¿ÐµÑÐ²ÑÐµ Ð±ÑÐ»Ð¸ ÑÐ¾Ð·Ð´Ð°Ð½Ñ Ð´Ð²Ðµ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½ÑÐµ Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð´Ð»Ñ ÑÐ°ÑÑÐµÑÐ¾Ð² Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ Ð¸ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº ÑÐ¸ÑÑÐµÐ¼Ñ Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð¸Ñ ÑÐ¸ÑÐ»ÐµÐ½Ð½Ð¾-Ð°Ð½Ð°Ð»Ð¸ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ Ð°Ð½Ð°Ð»Ð¸Ð·.
description: The object of the research is planar, three-link manipulator designed to work in low-gravitational effects. The purpose of work - study approach to obezveshivaniyu manipulators are copied by creating computer models. The study two computer models were created for the first time settlement system dynamics and dynamic characteristics, and held their numerical and analytical analysis.
title: Self-healing ThSiO4-ZrSiO4 system under conditions relevant to underground nuclear waste repositories
Creators: name: Svitlyk, Volodymyr
name: Weiss, Stephan
name: Garbarino, Gaston
name: Azzam, Salim Shams Aldin
name: Hübner, René
name: Worbs, Andreas
name: Huittinen, Nina
name: Hennig, Christoph
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Zircon
subject: ZrSiO4
subject: Thorium
subject: Water content
subject: Phase composition
subject: High pressure
subject: High temperature
classificationCode: 540
subject: Chemie und zugeordnete Wissenschaften

description: Two series of Th1-xZrxSiO4 phases were synthesized hydrothermally under weakly basic (pH = 8) and strongly acidic (pH = 1) conditions. Changes in pH were found to have a significant effect on experimental phase diagrams. Synthesis at pH = 8 favors the formation of Th-rich phases with resulting Th1-xZrxSiO4 solid solution for x = 0 – 0.5. Contrary, synthesis at pH = 1 results in the formation of pure end-members of the ThSiO4-ZrSiO4 pseudo-binary system separated by multiple miscibility gaps. Phases formed both under basic and acidic conditions were found to retain water, which can be discharged from the structure upon heating. A different high-pressure (HP) behaviour was found for Th-rich and Zr-rich solid solutions. While Th-rich Th0.9Zr0.1SiO4 and Th0.6Zr0.4SiO4 phases retain their stoichiometry and crystal structure upon compression at HP, a significant reduction of the Th occupancy related to a decrease of the Th-O distances is observed for the Th-poor Th0.26Zr0.74SiO4 phase at P > 8 GPa, with the subsequent formation of a Th-rich amorphous phase. The Th diffusion between the crystalline and amorphous phases was found to be fully reversible. This unique self-healing property makes these phases promising candidates for nuclear applications under extreme pressure and temperature conditions, in particular those found in underground repositories.
Some inequalities with combinatorial applications
Creators: name: Gordon, William Robert
Publisher: name: University of British Columbia
Year: 2012

description: Some inequalities of H. J. Ryser with combinatorial applications are generalized. Let f be a non-negative concave symmetric function on v-tuples of non-negative reals. If f has the property that when θa + (1- θ)b ∈ G[subscript f] = f[power -1] ({t:t > 0}), 0 < θ < 1, then f(θa + (1- θ)b) = θf(a) + (1-θ)f(b), then we say that f is strictly concave. (Similarly, if f is convex and has the property just mentioned, then we say that f is strictly convex). Let H be a non-negative hermitian matrix with eigenvalues λ₁, ..., λ[subscript v], where λ₁ ≧ ... ≧λ[subscript e] > λ[subscript e+1] = … = λ[subscript v] = 0. Let h be an integer, 1 < h, such that e ≦h ≦ v and define k and λ by k = trace (H)/h, λ[subscript h] ≦k + (h-1) λ ≦λ₁. Define the matrix B of order h by B = (k- λ)I + λJ, where I is the identity matrix all of whose entries are 1's. Let B₀ = B ∔ 0, where the matrix B₀ of order v is the direct sum of the matrix B of order h and the (v-h)-order zero matrix. Let f(H) denote f(λ₁, … , λ[subscript v]). Then we prove theorems of the following nature. THEOREM: The matrices H and B₀ satisfy f(H) ≦ f(B₀). If f is strictly concave and if (λ₁, ..., λ[subscript v]) ∈ G[subscript f] then equality holds if and only if H and B₀ have the same eigenvalues. If f is strictly concave and if for some integer z, G[subscript f] is the set of non-negative vectors with at least z positive coordinates and if k + (h-1) λ ≠ 0 and z ≦ h or k + (h-1)λ = 0 and z < h, then f(H) = f(B₀) if and only if H and B₀ have the same eigenvalues. If f is convex a similar theorem with the inequality reversed can be proved. We discuss various choices of the function f and indicate some applications of the results to some combinatorial problems.
ปัจจัยการยอมรับเทคโนโลยีที่ส่งผลต่อความพึงพอใจในการใช้แอปพลิเคชัน PEA Smart Plus ของการไฟฟ้าส่วนภูมิภาค
Creators: name: เกวลี พร้อมมูล
Publisher: name: คณะวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์
Year: 2023
Subjects: แอปพลิเคชัน
PEA Smart Plus
การยอมรับเทคโนโลยี
ความพึงพอใจ

description: วารสารวิจัยวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์, 7, 1, 170-181
title: Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach
Creators: name: Karami, Hosna
name: Soltani, Somaieh
name: Wolber, Gerhard
name: Sadigh-Eteghad, Saeed
name: Nikbakht, Roghaye
name: Farrokhi, Hanieh
name: Narimani, Farzaneh
name: Teimuri-Mofrad, Reza
name: Rashidi, Mohammad-Reza
Publisher: name: Freie Universität Berlin
Year: 2025
Subjects: subject: Alzheimer's disease therapeutics
subject: Multi-target neuroprotective
subject: Cholinesterase inhibitors
subject: Amyloid-beta interventions
subject: Neuromolecular mechanisms
subject: Aβ treated rat cognition improvement
classificationCode: 615
subject: Pharmakologie, Therapeutik

description: Introduction: Multi-target anti-Alzheimer's disease (AD) compounds are promising leads for the development of AD modifying agents. Ionic compounds containing quaternary ammonium moiety were synthesized, and their multi-targeted anti-AD effects were examined. Methods: Imidazole derivatives containing a quaternary ammonium moiety were synthesized and evaluated for their potential anti-Alzheimer properties using computational (in silico), cellular (in vitro), and animal (in vivo) models. The inhibition kinetics of both human acetylcholinesterase (hAChE) and butyrylcholinesterase (hBuChE) were assessed. Neuroprotective effects in amyloid-beta (Aβ)-exposed PC12 cells were also examined. Furthermore, the compounds' impact on Aβ-induced memory impairment in Wistar rats was evaluated, with a detailed analysis of the underlying mechanisms. Results: Compound 5g demonstrated acceptable cytotoxicity against human cells. This compound exhibited non-competitive dual inhibition of both hAChE and hBuChE. Additionally, compound 5g mitigated the morphological changes induced by amyloid-beta (Aβ) in PC12 cells and decreased cell mortality. It exhibited anti-oxidative stress properties, evident by reduction in reactive oxygen species (ROS) production, and inhibition of lipid peroxidation. The compound also down regulated the expression of pro-inflammatory genes IL-1β and TNF-α. In vitro studies validated compound 5g's ability to inhibit lactate dehydrogenase (LDH), attenuate neuroinflammation, and prevent the autophagy-apoptosis cascade. When administered to rats with Aβ-induced memory dysfunction, compound 5g enhanced cognitive function and improved spatial memory. In the hippocampi of treated rats, there was a noted downregulation of TNF-α and NF-kB. Furthermore, compound 5g counteracted the elevated activity of AChE. Molecular modeling validated the binding of compound 5g to both steric and catalytic sites of cholinesterase enzymes. Conclusion: The novel quaternary ammonium derivative, compound 5g, demonstrated multi-target anti-AD properties, as evidenced by in silico, in vitro and in vivo studies. Behavioral assessments and molecular analyses further confirmed its therapeutic efficacy in amyloid-beta (Aβ)-challenged rats.
Poa flaccidula
Creators: name: Cardona, Àngel Manuel Hernández
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Poa
Poa flaccidula

description: Poa flaccidula Boiss. et Reut.
(poa flàccida). De l’oest de la regió mediterrània. Creix en pedregars, penyalars, matolls i pastures, preferentment sobre substrats calcaris. És molt rara al massís de l’Obac, on ha estat descoberta recentment (Hernández & Comellas, 2021: 51).
description: Published as part of Cardona, Àngel Manuel Hernández, 2022, Catàleg actualitzat i claus d'identificació de les gramínies de Sant Llorenç del Munt i l'Obac (Barcelona), pp. 64-86 in Nemus 12 on page 73, DOI: 10.5281/zenodo.12170499
Interference effects in the X(4260) signal
Creators: name: van Beveren, Eef
name: Rupp, George
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We show that the long known puzzling branching ratios of open-charm decays in electron-positron annihilation can be reasonably described with a simple form factor, which strongly suppresses open channels far above threshold. Application to the electron-positron annihilation into J/psi+pion+pion data on the X(4260) enhancement recently reported by the BABAR Collaboration [arxiv:0808.1543] allows a good fit with a simple nonresonant cusp structure around the D(*)(s)+Dbar(*)(s) threshold. Moreover, we argue that a closer look at the data reveals an oscillatory pattern, which we model as an interference effect between a fast - OZI-allowed - and a slow - OZI-forbidden - J/psi+f(0)(980) mode. Other candidates for similar nonresonant enhancements are discussed.
description: 8 pages, regular LaTeX, 4 figures
ศักยภาพในการรองรับการท่องเที่ยวเชิงสุขภาพของจังหวัดภูเก็ต
Creators: name: หิรัญญา กลางนุรักษ์
Publisher: name: คณะวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์
Year: 2023
Subjects: การท่องเที่ยวเชิงสุขภาพ
ศักยภาพในการรองรับ
จังหวัดภูเก็ต

description: วารสารวิจัยวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์, 7, 1, 182-192
การตลาดดิจิทัลในยุคที่ท้าทาย บทบาทความได้เปรียบทางการแข่งขันของผู้ประกอบการไทย
Creators: name: เกศสิริ นวลใยสวรรค์
Publisher: name: คณะวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์
Year: 2023
Subjects: การตลาดดิจิทัล;ความได้เปรียบทางการแข่งขัน;ผู้ประกอบการ

description: วารสารวิจัยวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์, 7, 1, 193-207
A comprehensive analysis of Trastuzumab-induced signaling suggests the role of HER2 in several cell processes and highlights alternative targets for HER2- positive breast cancer therapy
Creators: name: Tacchetti, Carlo
name: Bagnato, Paola
name: Locatelli, Alberta
name: Mazza, Davide
name: Gaviraghi, Marco
name: Castagnola, Patrizio
name: Rabellino, Andrea
name: Daniele, Tiziana
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: 20-30% of breast cancers display a ErbB2 (HER2) gene amplification or protein over-expression. HER2 is constitutively activated receptor belonging to the ErbB RTK family, which comprises also ErbB1 (EGFR or HER1), ErbB3 (HER3), and ErbB4 (HER4). HER2 triggers the activation of ERK1/2 MAPK and AKT signaling pathways. Although most of our knowledge on HER2 is mutuated from EGFR (1-3), due to the absence of an HER2 ligand, the use of drugs targeting HER2 (4) has shed light in its specific role in endocytosis and trafficking. Trastuzumab (TZ, a humanized inhibitory antibody to HER2) is a front line drug for the therapy of HER2-positive breast cancers, and has improved clinical course and overall prognosis; however it faces frequent primary or acquired resistance involving the AKT pathway. Our goal is to dissect the molecular events downsream TZ treatment and identify key hits for an alternative target therapy bypassing the resistance. TZ treatment induces the activation of the ERK1/2 signaling pathway and the downregulation of AKT phosphorylation. Our results demonstrate for the first time that ERK1/2 phosphorylation drives the signaling leading to the AKT de-phosphorylation. We have excluded a role for the kinase pathway controlling AKT phosphorylation identifying a role for Ser/Thr phosphatases. This pathway is uniquely activated by the TZ-HER2 interaction. Therefore we are now persuing the identification of a key regulator of this pathway to screen a library of orphan drugs in search of a putative hit candidate. Beside the potential interest in the identification of alternative therapeutic strategies to HER2 positive breast cancer, the use of TZ in our studies has highlighted the role of HER2 in control- ling new and relevant physiological cell processes, such as endocytosis and invasion
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
title: Chiral-Induced Spin Selectivity in Photo-Induced Electron Transfer: investigating charge and spin dynamics in a master equation framework
Creators: name: Macaluso, Emilio
name: Chiesa, Alessandro
name: Santini, Paolo
name: Bittl, Robert
name: Carretta, Stefano
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: Electron transfer
subject: Photoexcitations
subject: Spin-spin interactions
subject: Exchange interactions
subject: Density-matrix
subject: Charge recombination
subject: Quantum Zeno effect
subject: Quantum information
subject: Quantum computing
subject: Spintronics
classificationCode: 530
subject: Physics

description: Investigating the role of chiral-induced spin selectivity in the generation of spin correlated radical pairs in a photoexcited donor–chiral bridge–acceptor system is fundamental to exploit it in quantum technologies. This requires a minimal master equation description of both charge separation and recombination through a chiral bridge. To achieve this without adding complexity and entering in the microscopic origin of the phenomenon, we investigate the implications of spin-polarizing reaction operators to the master equation. The explicit inclusion of coherent evolution yields non-trivial behaviors in the charge and spin dynamics of the system. Finally, we apply this master equation to a setup comprising a molecular qubit attached to the donor–bridge–acceptor molecule, enabling qubit initialization, control, and read-out. Promising results are found by simulating this sequence of operations assuming realistic parameters and achievable experimental conditions.
The wrap partial restrain stress, an animal model of the irritable bowel syndrome: immunohistochemical and functional characterization
Creators: name: Traini, Chiara
name: Evangelista, Stefano
name: Faussone-Pellegrini, Maria Simonetta
name: Vannucchi, Giuliana
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Several animal models have been proposed to mimic the human irritable bowel syndrome (IBS) all based on two etio-pathogenic hypotheses: infection and stress, both responsible for the development of a local inflammation. We investigated the wrap partial restrain stress (WRS) animal model with the aim to evaluate its validity in understanding the human IBS. Male Wistar rats were used and WRS was maintained for 2h. Abdominal contractions (AC) were recorded by a distension balloon in the colon-rectum. The number of faecal pellets and their total weight were determined. Colonic specimens from both groups were examined by routine histology, immunohistochemistry and western blot (WB). WRS animals were characterized by: 1) a statistically significant increase in the number of AC and in the mean number and mean weight of faecal pellets; 2) the presence of large clusters of mononucleated cells and a significant increase in eosinophilic granulocytes and mast cells in the mucosa; 3) reduction of GLP1r-immunoreactivity (IR) located at the basolat- eral periphery and the Golgi level of the cells of the glandular funds; 4) an increase in CGRP-IR in the lamina propria; 5) no significant difference in the muscle wall for Cav1, L- type Ca+2-channels, Mr2, NK1r and NK2r; 6) a significant decrease in the myenteric and a significant increase in the submucous NK1-IR neuron number; 7) a significant decrease in Substance P-IR in the myenteric plexus and muscle coat; 8) a significant decrease in myenteric and submucous nNOS-IR neuron number; 9) no difference in ChAT-IR neurons of both enteric plexuses; 10) a reduction in S-100-IR in the entire colonic wall; 11) no difference in the total number of neurons evaluated by the pan-neuronal marker PGP 9.5; 12) no change of all the ICC populations. The functional data are in favor of a lowering in the colonic wall distention threshold; the morphological results obtained in the lamina propria demonstrate the presence of a local inflammation, particularly intense at the level of the mucosa. Both of these findings agree with the hypothesis that inflammation might have a main role in the insurgence and maintenance of the typical IBS symptoms and support the validity of our WRS model. Moreover, while the smooth muscle cells do not show any significant variation, numerous and consistent changes in the excitatory, inhibitory and NK1r-IR neurons are detected.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Three hits are superior than one: multiple Akt inhibition as a new therapeutic strategy in T-ALL
Creators: name: Ultimo, Simona
name: Simioni, Carolina
name: Cani, Alice
name: Martelli, Alberto
name: Zauli, Giorgio
name: Alameen, Ayman A.M.
name: Capitani, Silvano
name: Neri, Luca M.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: T-acute lymphoblastic leukemia; Akt; Perifosine; GSK690693; MK-2206

description: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive neoplastic disorder of T lymphocytes characterized by a poor clinical outcome, especially for relapsed patients [1]. The PI3K/Akt/mTOR signaling pathway is crucial for cell growth and survival in many types of solid and blood tumors, including T-ALL, influencing the response to therapeutic treatments [2]. The PI3K/Akt/mTOR network is often hyperactivated in T-ALL and therefore could constitute a target of inhibitory strate- gies, such as those that use small molecules inhibitors (SMI). The combined administration of multiple drugs is an attractive attempt to overcome drug resistance and to improve clinical outcome [3]. We tested in a panel of T-ALL cell lines three drugs directed against Akt with totally different modes of action: GSK690693, ATP- competitive, MK-2206, allosteric, and Perifosine, alkylphospholipid-Akt inhibitor. We showed that multiple Akt inhibition with this drug combination in T-ALL cell lines was cytotoxic and displayed a synergistic effect which was also related to the timing and the sequence of every drug administration. In fact, our findings showed that 6h of Perifosine pre-treatment followed by the combined administration of MK-2206 and GSK690693 for 30 min was necessary for the complete switch off of the activated protein. This combination caused a potent cell cycle arrest in G0/G1 phase and induced apoptosis and autophagy with more efficacy than single or double drug administration. In conclusion, our data demonstrated that this pharmacological strategy could represent a new promising treatment for patients affected by T-ALL with hyperacti- vated PI3K/Akt/mTOR signaling pathway.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
An Intra-Arterial Therapeutic Route to the Trigeminal Nerve Ganglion
Creators: name: Zeenat Qureshi Stroke Institutes
Publisher: name: Zenodo
Year: 2023

description: I read with interest the article by Qureshi et al. [1] in January issue of Journal of Neuroimaging regarding intra-arterial delivery of medication for suppressing trigeminal nerve ganglion function in patients with refractory trigeminal neuralgia. Intra-arterial route has not been used for diagnostic or therapeutic purposes despite nerves and nerve ganglions being supplied by segmental arteries and the vasa nervorum. The investigators had used intra-arterial lidocaine in doses up to 50 mg in the middle meningeal artery territory adjacent to the arterial branch that supplies the trigeminal nerve ganglion and demonstrated short-term clinical improvement as anticipated. The artery of Qureshi [2] described earlier may also be used for delivery of neurolysis agents such as alcohol or antineoplastic agents with neurotoxic properties to the trigeminal nerve ganglion for more sustained benefit in patients with refractory trigeminal neuralgia. However, the artery of Qureshi does not appear large enough for selective catheterization and microcatheter has to be placed in the middle meningeal artery. Therefore, one must expect that certain amounts of injected agents are going to be distributed in the petrosal artery which courses posteriorly and anterior and posterior dural branches of the intracranial division of middle meningeal artery [2]. What remains to be identified is whether there are adverse consequences of such a distribution with previously mentioned agents. The petrosal branch of middle meningeal artery supplies the facial nerve and anastomoses with the stylomastoid branch of the posterior auricular artery and inadvertent delivery of such agents may be of concern. Furthermore, most data regarding arterial supply are derived from patients with trigeminal neuralgia. Due to hyperactivity of the trigeminal nerve ganglion, the arterial supply may be more pronounced with an enlargement of the artery of Qureshi. In normal persons, the artery may actually be smaller. Additional studies would also have to clarify whether the artery of Qureshi (to trigeminal nerve ganglion) can originate from other arteries such as accessory middle meningeal artery as part of normal variation between individuals
Galassie con nuclei quieti, ma non troppo
Creators: Francesca Panessa
Publisher: name: Media Inaf
Year: 2019

Gli Agn radio quieti, fino a oggi un po’ trascurati, con Ska saranno sempre più al centro dell'attenzione e il loro studio sarà fondamentale per capire la fisica e l’evoluzione delle galassie. Ospitiamo un editoriale sull’argomento di Francesca Panessa (Inaf Iaps Roma), autrice insieme a Ranieri Baldi (University of Southampton) di una review pubblicata oggi su Nature Astronomy
“…he’s going to be facing the same things that he faced prior to being locked up”: perceptions of service needs for substance use disorders
Creators: name: Beeler, Sara
name: Renn, Tanya
name: Pettus, Carrie
Publisher: name: University of Illinois at Chicago
Year: 2023
Subjects: Uncategorized

description: BACKGROUND: High rates of substance use disorders (SUDs) exist among justice-involved populations (i.e., persons incarcerated or recently released). SUD treatment is crucial for justice-involved populations as unmet treatment need increases reincarceration risk and impacts other behavioral health sequalae. A limited understanding of health needs (i.e. health literacy) can be one reason for unmet treatment needs. Social support is critical to seeking SUD treatment and post-incarceration outcomes. However, little is known about how social support partners understand and influence SUD service utilization among formerly incarcerated persons. METHODS: This mixed method, exploratory study utilized data from a larger study comprised of formerly incarcerated men (n = 57) and their selected social support partners (n = 57) to identify how social support partners understand the service needs of their loved ones recently released from prison who returned to the community with a diagnosis of a SUD. Qualitative data included 87 semi-structured interviews with the social support partners covering post-release experiences with their formerly incarcerated loved one. Univariates were conducted on the quantitative service utilization data and demographics to complement the qualitative data. RESULTS: Majority of the formerly incarcerated men identified as African American (91%) averaging 29 years of age (SD = 9.58). Most social support partners were a parent (49%). Qualitative analyses revealed that most social support partners avoided using or did not know the language to use regarding the formerly incarcerated person's SUD. Treatment needs were often attributed to focus on peer influences and spending more time at their residence/housing. Analyses did reveal that when treatment needs were recommended in the interviews, social support partners reported employment and education services to be most needed for the formerly incarcerated person. These findings align with the univariate analysis with their loved ones reporting employment (52%) and education (26%) as their most reported service utilized post-release, compared to only 4% using substance abuse treatment. CONCLUSION: Results provide preliminary evidence suggesting social support partners do influence the types of services accessed by formerly incarcerated persons with SUD. The findings of this study emphasize the need for psychoeducation during and after incarceration for individuals with SUDs and their social support partners.
Detection of hidden vertical root fracture by stereomicroscope
Creators: name: Bernardi, Sara
name: Zeka, Keti
name: Fantozzi, Giulia
name: Caruso, Silvia
name: Gatto, Roberto
name: Continenza, Maria Adelaide
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Maxillary molar; crack line; stereomicroscopy

description: The vertical root fractures resulting as from trauma, as from the “cracked tooth syndrome”, are spotted within the “iatrogenic periodontal lesions” according to the Al-Fouzan (1) classification. The stereo microscope, an optical microscope variant typically exploiting the light reflected from the surface of an object rather than that transmitted through it (2), in the reported case has revealed the best tool to perform the resolving three-dimensional examination of the tooth. Aim of this paper is to describe a vertical root fracture, not otherwise detectable. A second upper molar, has been endodontically treated, because of the presence of an endo-periodontal lesion. Even though the treatment was performed according the standard protocol, after two years the lesion persisted and the tooth was extracted. After the extraction, the tooth was diaphanized to be observed with the stereomicroscope (Leica LED2000). The investigation clearly showed a vertical fracture, starting directly from the cervical line and a small hole on the distal surface of the root palatal cone. Mean values of measurements taken in 15 randomly points at 1x, 4x and 8x magnification were made. The fracture resulted to be long 9,79 mm and to have a mean width of 0,37 + 0,07 mm externally, and 0,15 + 0,02 mm internally. The mean area of the hole resulted of 0,85 mm2. All the analytical procedure was validated by t-student test, showing a p value < 0,0001. This vertical root fracture represented the unexpected pathway between the pulp and periodontal tissues and sure it caused the endodontic treatment failure, with tooth loss. It appears clear that a good diagnosis, following exactly the proto- col stated in the literature, together with the patient’s compliance, are crucial basis to face such clinical challenge.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Accretion Rates of Planetesimals by Protoplanets Embedded in Nebular Gas
Creators: name: Tanigawa, Takayuki
name: Ohtsuki, Keiji
Publisher: name: arXiv
Year: 2009
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: When protoplanets growing by accretion of planetesimals have atmospheres, small planetesimals approaching the protoplanets lose their energy by gas drag from the atmospheres, which leads them to be captured within the Hill sphere of the protoplanets. As a result, growth rates of the protoplanets are enhanced. In order to study the effect of an atmosphere on planetary growth rates, we performed numerical integration of orbits of planetesimals for a wide range of orbital elements and obtained the effective accretion rates of planetesimals onto planets that have atmospheres. Numerical results are obtained as a function of planetesimals' eccentricity, inclination, planet's radius, and non-dimensional gas-drag parameters which can be expressed by several physical quantities such as the radius of planetesimals and the mass of the protoplanet. Assuming that the radial distribution of the gas density near the surface can be approximated by a power-law, we performed analytic calculation for the loss of planetesimals' kinetic energy due to gas drag, and confirmed agreement with numerical results. We confirmed that the above approximation of the power-law density distribution is reasonable for accretion rate of protoplanets with one to ten Earth-masses, unless the size of planetesimals is too small. We also calculated the accretion rates of planetesimals averaged over a Rayleigh distribution of eccentricities and inclinations, and derived a semi-analytical formula of accretion rates, which reproduces the numerical results very well. Using the obtained expression of the accretion rate, we examined the growth of protoplanets in nebular gas. We found that the effect of atmospheric gas drag can enhance the growth rate significantly, depending on the size of planetesimals.
description: 41 pages, 14 figures, accepted for publication in Icarus
A typical case of  Leighâs disease: Case Report
Creators: name: UDIYA, ALOK
Publisher: name: EURORAD
Year: 2015
Subjects: subject: Neuroradiology brain
subject: MR
subject: Imaging sequences
subject: Biological effects
subject: Blood

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 4 years
description: Clinical History: Ã¯ÂÂ¡	Four year old male child presented with history of regression of milestones and startle response along with rhythmic repetitive movement of upper limb since -15 month of age. EEG was normal with generalised spike at the time of sound induced startle. ... Final Diagnosis: Leighs disease( Mitochondrial disorder)
title: Modalities of Fictionality. Kalīla wa-Dimna's Readers.
Creators: name: Stephan, Johannes
Publisher: name: Freie Universität Berlin
Year: 2022
Subjects: subject: fictionality
subject: fiction
subject: hermeneutics
subject: Kalila wa-Dimna
subject: adab compilations
subject: poetics
subject: Ibn Qutayba
subject: Ibn 'Abd Rabih
subject: al-Ya`qubi
subject: al-Biruni
subject: al-Yamani
subject: Ibn Sina
subject: Ibn Rushd
subject: AnonymClassic publication
classificationCode: 892
subject: Afro-Asiatic literatures Semitic

description: The book of Kalīla wa-Dimna has been apprehended in variegated ways: as an originally Indian book, one of the first Arabic adab works, as a mirror for princes and a collection of fables. In spite of varying construals of Kalīla wa-Dimna, until recently there is one shared denominator among modern textual scholarship: it is a fictional narrative. Although such interpretation seems intuitive to a modern reader, it is questionable when taking a historical perspective. Since there is no precise equivalent of "fictionality" in the classical context, the concept can neither be naturally assumed, nor be approached as a single unitary notion that we have to simply translate and then seek to find by identifying “signals” or “signposts” of fiction/fictionality. Building upon approaches that attempt to reconstruct premodern modes of understanding and using textual production, in this article, I suggests to conceptualize fictionality as a hermeneutical category which encompasses different perspectives of what about and in a text is fictional. After shedding light on the problem of fiction/-ality in Arabic before modernity and expounding the hermeneutics of fictionality, I will draw from three types of references to Kalīla wa-Dimna in the Arabic tradition between 750 and 1300 AD: first, the notion of practical wisdom and its independence from demonstrable referentiality; second, the problem of reliable transmission; third, the notion of parables and invented content.
Aumenta la tensione sulla costante di Hubble
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2019

L’annuncio arriva dal team del premio Nobel Adam Riess: l’ultima stima ottenuta con metodi astrofisici è pari a 74.03 ± 1.42 km/s/Mpc. Raggiunta grazie alla misura precisa della distanza di 70 cefeidi della Grande Nube di Magellano, rafforza sempre più la significatività della discrepanza con le stime cosmologiche
Osservato in Italia l’evento più raro di sempre
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2019

Registrato nei Laboratori nazionali del Gran Sasso, è un particolare tipo di decadimento dell’isotopo xenon-124: il suo tempo di dimezzamento è risultato pari a oltre mille miliardi di volte l’età dell’universo. Il risultato è pubblicato su Nature
Discomfort, fatigue and work-related musculoskeletal disorders associated with prolonged standing among Malaysian manufacturing workers: A mini review
Creators: name: Zutiqa Aqmar Yazuli
name: Karmegam Karuppiah
name: Kumar, Enoch
name: Shamsul Bahri Md Tamrin
name: Sivasankar Sambasivam
Publisher: name: Research and Development Office, Prince of Songkla University
Year: 2019
Subjects: WMSDs
prolonged standing
ergonomics
discomfort
fatigue

description: Songklanakarin Journal of Science and Technology, 41, 2, 271-275
The many vacua of gauged extended supergravities
Creators: name: Fischbacher, Thomas
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A novel method is presented which employs advanced numerical techniques used in the engineering sciences to find and study the properties of nontrivial vacua of gauged extended supergravity models. While this method only produces approximate numerical data rather than analytic results, it overcomes the previous limitation of only being able to find vacua with large residual unbroken gauge symmetry groups. The effectiveness of this method is demonstrated by applying it to the technically most challenging D>=3 scalar potential -- that of SO(8) X SO(8) gauged N=16 Chern-Simons Supergravity in D=3. Extensive data on the properties of 99 different vacua (92 of them new) of this model are given. Furthermore, techniques are briefly discussed which should allow using this numerical information as an input to the construction of semi-automatic stringent analytic proofs on the locations and properties of vacua. It hence is argued that these combined techniques presumably are powerful enough to systematically map all the nontrivial vacua of every supergravity model.
description: 66 pages, code to reproduce results can be obtained by downloading paper's source, as described in the text
Registrato da InSight il primo “martemoto”
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2019

È un segnale di probabile origine sismica rilevato il 6 aprile scorso, 128esimo giorno marziano del lander Nasa sul Pianeta rosso. Segnali come questo consentiranno in futuro agli scienziati di mettere a punto modelli sull’interno di Marte e, più in generale, sulla formazione dei pianeti rocciosi
title: The gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis
Creators: name: Yuu, Elizabeth Y.
name: Bührer, Christoph
name: Eckmanns, Tim
name: Fulde, Marcus
name: Herz, Michaela
name: Kurzai, Oliver
name: Lindstedt, Christin
name: Panagiotou, Gianni
name: Piro, Vitor C.
name: Radonic, Aleksandar
name: Renard, Bernhard Y.
name: Reuss, Annicka
name: Siliceo, Sara Leal
name: Thielemann, Nadja
name: Thürmer, Andrea
name: Vorst, Kira Van
name: Wieler, Lothar H.
name: Haller, Sebastian
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Preterm infants
subject: Antibiotics
subject: Infloran
subject: Mice model
subject: Microbiome
subject: Resistome
subject: Mycobiome
classificationCode: 630
subject: Landwirtschaft und verwandte Bereiche

description: Background Enhancing our understanding of the underlying influences of medical interventions on the microbiome, resistome and mycobiome of preterm born infants holds significant potential for advancing infection prevention and treatment strategies. We conducted a prospective quasi-intervention study to better understand how antibiotics, and probiotics, and other medical factors influence the gut development of preterm infants. A controlled neonatal mice model was conducted in parallel, designed to closely reflect and predict exposures. Preterm infants and neonatal mice were stratified into four groups: antibiotics only, probiotics only, antibiotics followed by probiotics, and none of these interventions. Stool samples from both preterm infants and neonatal mice were collected at varying time points and analyzed by 16 S rRNA amplicon sequencing, ITS amplicon sequencing and whole genome shotgun sequencing. Results The human infant microbiomes showed an unexpectedly high degree of heterogeneity. Little impact from medical exposure (antibiotics/probiotics) was observed on the strain patterns, however, Bifidobacterium bifidum was found more abundant after exposure to probiotics, regardless of prior antibiotic administration. Twenty-seven antibiotic resistant genes were identified in the resistome. High intra-variability was evident within the different treatment groups. Lastly, we found significant effects of antibiotics and probiotics on the mycobiome but not on the microbiome and resistome of preterm infants. Conclusions Although our analyses showed transient effects, these results provide positive motivation to continue the research on the effects of medical interventions on the microbiome, resistome and mycobiome of preterm infants.
title: ÐÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÐ´Ð° Ð½Ð° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¸ Ð½ÐµÑÑÐµÐ³Ð°Ð·Ð¾Ð²Ð¾Ð¹ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾ÑÑÐ¸ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ "ÐÐ°Ð·Ð¿ÑÐ¾Ð¼Ð½ÐµÑÑÑ ÐÐ¢Ð¦")
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð·Ð·Ð¸Ð½, Ð Ð¾Ð¼Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð¼ÐµÑÐ¾Ð´Ñ Ð½Ð¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑÑÐ´Ð°
Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½ÑÐ¹ ÑÑÑÐ´
Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ðµ Ð½ÐµÑÑÐµÐ³Ð°Ð·Ð¾Ð²Ð¾Ð¹ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾ÑÑÐ¸

description: Ð¦ÐµÐ»ÑÑ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ ÑÐ²Ð»ÑÐµÑÑÑ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ Ð²Ð¾Ð·Ð¼Ð¾Ð¶Ð½Ð¾ÑÑÐ¸ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐºÑÐ¿ÐµÑÑÐ½Ð¾Ð³Ð¾ Ð¼ÐµÑÐ¾Ð´Ð° Ð´Ð»Ñ ÑÑÑÐ°Ð½Ð¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð½Ð¾ÑÐ¼ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½ÑÑ Ð·Ð°ÑÑÐ°Ñ ÑÐ¾ÑÑÑÐ´Ð½Ð¸ÐºÐ¾Ð², Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¹ Ð¿Ð¾ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÑÐ¸ÑÑÐµÐ¼Ñ Ð½Ð¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÐ´Ð° Ð½Ð° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¸ Ð½ÐµÑÑÐµÐ³Ð°Ð·Ð¾Ð²Ð¾Ð¹ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾ÑÑÐ¸ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«ÐÐ°Ð·Ð¿ÑÐ¾Ð¼Ð½ÐµÑÑÑ ÐÐ°ÑÑÐ½Ð¾-Ð¢ÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¦ÐµÐ½ÑÑÂ»). ÐÐ»Ñ Ð´Ð¾ÑÑÐ¸Ð¶ÐµÐ½Ð¸Ñ ÑÐµÐ»Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° Ð¸ÑÑÐ¾ÑÐ¸Ñ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð¿Ð¾ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ Ð½Ð¾ÑÐ¼, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ð½Ð¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸Ð½ÑÐµÐ»Ð»ÐµÐºÑÑÐ°Ð»ÑÐ½Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸. ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ ÑÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð¸Ñ ÑÐµÑÐµÐ½Ð¸Ñ, Ð° Ð¸Ð¼ÐµÐ½Ð½Ð¾ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¿Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ ÑÐºÑÐ¿ÐµÑÑÐ½Ð¾Ð³Ð¾ Ð´ÐµÐ»ÑÑÐ¸Ð¹ÑÐºÐ¾Ð³Ð¾ Ð¼ÐµÑÐ¾Ð´Ð° Ð² ÑÑÐ»Ð¾Ð²Ð¸ÑÑ Ð¾ÑÑÑÑÑÑÐ²Ð¸Ñ Ð½Ð°ÐºÐ¾Ð¿Ð»ÐµÐ½Ð½Ð¾Ð¹ ÑÑÐ°ÑÐ¸ÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð±Ð°Ð·Ñ Ð½Ð° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¸ Ð½ÐµÑÑÐµÐ³Ð°Ð·Ð¾Ð²Ð¾Ð¹ Ð¿ÑÐ¾Ð¼ÑÑÐ»ÐµÐ½Ð½Ð¾ÑÑÐ¸. ÐÑÐµÐ´Ð¿Ð¾Ð»Ð°Ð³Ð°ÐµÐ¼ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¾Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð½ÑÑ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹: ÑÐ²ÐµÐ»Ð¸ÑÐµÐ½Ð¸Ðµ Ð¿ÑÐ¾Ð·ÑÐ°ÑÐ½Ð¾ÑÑÐ¸ Ð¸ ÑÐ¼ÐµÐ½ÑÑÐµÐ½Ð¸Ðµ ÑÑÐ±ÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¿ÑÐ¸ Ð¾ÑÐµÐ½ÐºÐµ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐ¾ÑÑÑÐ´Ð½Ð¸ÐºÐ°, ÑÐ»ÑÑÑÐµÐ½Ð¸Ðµ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÐµÑÑÑÑÐ½ÑÑ Ð·Ð°ÑÑÐ°Ñ, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ðµ Ð¿ÐµÑÐ²Ð¸ÑÐ½Ð¾Ð¹ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð±Ð°Ð·Ñ Ð´Ð»Ñ Ð´Ð°Ð»ÑÐ½ÐµÐ¹ÑÐµÐ¹ ÑÐ°Ð±Ð¾ÑÑ Ð¿Ð¾ ÑÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÑÑÐ´Ð¾Ð²Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸.
title: Ð Ð°ÑÑÐµÑ Ð¿Ð»Ð°Ð²Ð½Ð¾ÑÑÐ¸ Ñ Ð¾Ð´Ð° Ð³ÑÑÐµÐ½Ð¸ÑÐ½ÑÑ Ð¼Ð°ÑÐ¸Ð½
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¾Ð¹ÐºÐ¾Ð², ÐÐ½Ð°ÑÐ¾Ð»Ð¸Ð¹
name: ÐÐ¾Ð»ÐºÐ¾Ð², Ð®ÑÐ¸Ð¹
name: Ð Ð¾Ð»Ð»Ðµ, ÐÐ»Ð°Ð´Ð¸Ð¼Ð¸Ñ
Publisher: name: ÐÐÐ
Year: 1990
Subjects: ÐÑÑÐµÐ½Ð¸ÑÐ½ÑÐµ Ð¼Ð°ÑÐ¸Ð½Ñ

description: Ð ÑÑÐµÐ±Ð½Ð¾Ð¼ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ð¸ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¿Ð¾Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ð¸ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÑÐ°ÑÑÐµÑÐ¾Ð², ÑÐ²ÑÐ·Ð°Ð½Ð½ÑÑ Ñ Ð¾ÑÐµÐ½ÐºÐ¾Ð¹ Ð¿Ð»Ð°Ð²Ð½Ð¾ÑÑÐ¸ ÑÐ¾Ð´Ð° ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½ÑÑ Ð³ÑÑÐµÐ½Ð¸ÑÐ½ÑÑ Ð¼Ð°ÑÐ¸Ð½. ÐÐ½Ð¸Ð³Ð° Ð¿ÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð° Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² Ð²ÑÑÐ·Ð¾Ð², Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ ÑÐ°ÑÑÐµÑ Ð¸ ÐºÐ¾Ð½ÑÑÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÐ°Ð½ÑÐ¿Ð¾ÑÑÐ½ÑÑ Ð³ÑÑÐµÐ½Ð¸ÑÐ½ÑÑ Ð¼Ð°ÑÐ¸Ð½, Ð² ÐºÐ°ÑÐµÑÑÐ²Ðµ ÑÑÐºÐ¾Ð²Ð¾Ð´ÑÑÐ²Ð° Ðº ÐºÑÑÑÐ¾Ð²Ð¾Ð¼Ñ Ð¸ Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½Ð¾Ð¼Ñ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ. ÐÐ½Ð° Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð² ÑÐµÐ±Ñ Ð¾ÑÐ½Ð¾Ð²Ñ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ ÑÐ°ÑÑÐµÑÐ½Ð¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿Ð¾Ð´ÑÐµÑÑÐ¾ÑÐ¸Ð²Ð°Ð½Ð¸Ñ Ð³ÑÑÐµÐ½Ð¸ÑÐ½Ð¾Ð¹ Ð¼Ð°ÑÐ¸Ð½Ñ, Ð¾ÑÐµÐ½Ð¾ÑÐ½ÑÐµ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÑ Ð¿Ð»Ð°Ð²Ð½Ð¾ÑÑÐ¸ ÑÐ¾Ð´Ð° Ð¸ Ð¿ÑÐ¸Ð¼ÐµÑÑ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÑÐ°ÑÑÐµÑÐ¾Ð² Ð½Ð° Ð­ÐÐ.
Role of decomposition products in the oxidation of cyclohexene using a manganese(III) complex
Creators: name: Zand, Zahra
name: Mousazade, Younes
name: Arevalo, Ryan
name: Bagheri, Robabeh
name: Reza Mohammadi, Mohammad
name: Bikas, Rahman
name: Chernev, Petko
name: Aleshkevych, Pavlo
name: VANDICHEL, MATTHIAS
name: Song, Zhenlun
name: Dau, Holger
name: Mahdi Najafpour, Mohammad
Publisher: name: University of Limerick
Year: 2023
Subjects: subject: Chemical sciences
subject: FOS: Chemical sciences

description: Metal complexes are extensively explored as catalysts for oxidation reactions; molecular-based mechanisms are usually proposed for such reactions. However, the roles of the decomposition products of these materials in the catalytic process have yet to be considered for these reactions. Herein, the cyclohexene oxidation in the presence of manganese(III) 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine chloride tetrakis(methochloride) (1) in a heterogeneous system via loading the complex on an SBA-15 substrate is performed as a study case. A molecular-based mechanism is usually suggested for such a metal complex. Herein, 1 was selected and investigated under the oxidation reaction by iodosylbenzene or (diacetoxyiodo)benzene (PhI(OAc)2). In addition to 1, at least one of the decomposition products of 1 formed during the oxidation reaction could be considered a candidate to catalyze the reaction. First-principles calculations show that Mn dissolution is energetically feasible in the presence of iodosylbenzene and trace amounts of water.
Galassica: a Recanati si celebra l’infinito
Creators: Davide Coero Borga
Publisher: name: Media Inaf
Year: 2019

Dal 25 al 27 aprile nel centro storico della cittadina marchigiana si fa festa ai 200 anni de “L’infinito” di Leopardi e ai 20 anni dell’Istituto nazionale di astrofisica. Tre giorni di incontri con la scienza, serate al telescopio, mostre e laboratori
Size effects in copper whiskers
Creators: name: Moore, Zelma Esther
Publisher: name: University of British Columbia
Year: 2011

description: Whiskers were grown by the hydrogen reduction of cupric chloride. Tensile tests were performed on the whiskers, some of which were long enough to divide into two or three parts. After the whisker yielded ("primary tests") they were retested ("secondary tests") after removal of the deformed region. In order to see if length had any effect on yield stress, a normalizing proceedure was established to convert the yield stress measured at any diameter d to an equivalent whisker with d = 10 μ. No observable length dependence of yield stress was found for either primary tests or secondary tests. The diameter dependence of yield stress was found to depend on the type of tests. For primary tests, the yield stress was inversely proportional to d¹‧⁶, while for secondary tests, inversely proportional to d²‧⁵. A dislocation mechanism to explain this was proposed in terms of only a part of the cross-sectional area (a small annular ring at the periphery of the whisker) taking part in the deformation. This mechanism was suitable only if the whiskers were assumed to be initially free of dislocations. A decrease in the value of Young's Modulus of about 30% from the normal values was observed for whiskers subjected to a secondary test.
Rischio geomagnetico, il Mediterraneo s’attrezza
Creators: Marco Malaspina
Publisher: name: Media Inaf
Year: 2019

Si chiama “Space Weather User Needs for the Mediterranean Region” ed è un progetto approvato dall’Agenzia spaziale europea per costituire una rete di servizi per il meteo spaziale dedicata all’area mediterranea. Ne parliamo con il coordinatore italiano, Mauro Messerotti dell’Inaf di Trieste
Dynamical model of DNA-protein interaction: effect of protein charge distribution and mechanical properties
Creators: name: Florescu, Ana-Maria
name: Joyeux, Marc
Publisher: name: arXiv
Year: 2009
Subjects: subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The mechanical model based on beads and springs, which we recently proposed to study non-specific DNA-protein interactions [J. Chem. Phys. 130, 015103 (2009)], was improved by describing proteins as sets of interconnected beads instead of single beads. In this paper, we first compare the results obtained with the updated model with those of the original one and then use it to investigate several aspects of the dynamics of DNA sampling, which could not be accounted for by the original model. These aspects include the effect on the speed of DNA sampling of the regularity and/or randomness of the protein charge distribution, the charge and location of the search site, and the shape and deformability of the protein. We also discuss the efficiency of facilitated diffusion, that is, the extent to which the combination of 1D sliding along the DNA and 3D diffusion in the cell can lead to faster sampling than pure 3D diffusion of the protein.
description: accepted in JCP