Front-end receiver for miniaturised ultrasound imaging
Creators: name: Peyton, Graham
Publisher: name: Imperial College London
Year: 2017

description: Point of care ultrasonography has been the focus of extensive research over the past few decades. Miniaturised, wireless systems have been envisaged for new application areas, such as capsule endoscopy, implantable ultrasound and wearable ultrasound. The hardware constraints of such small-scale systems are severe, and tradeoffs between power consumption, size, data bandwidth and cost must be carefully balanced. To address these challenges, two synthetic aperture receiver architectures are proposed and compared. The architectures target highly miniaturised, low cost, B-mode ultrasound imaging systems. The first architecture utilises quadrature (I/Q) sampling to minimise the signal bandwidth and computational load. Synthetic aperture beamforming is carried out using a single-channel, pipelined protocol in order to minimise system complexity and power consumption. A digital beamformer dynamically apodises and focuses the data by interpolating and applying complex phase rotations to the I/Q samples. The beamformer is implemented on a Spartan-6 FPGA and consumes 296mW for a frame rate of 7Hz. The second architecture employs compressive sensing within the finite rate of innovation (FRI) framework to further reduce the data bandwidth. Signals are sampled below the Nyquist frequency, and then transmitted to a digital back-end processor, which reconstructs I/Q components non-linearly, and then carries out synthetic aperture beamforming. Both architectures were tested in hardware using a single-channel analogue front-end (AFE) that was designed and fabricated in AMS 0.35μm CMOS. The AFE demodulates RF ultrasound signals sequentially into I/Q components, and comprises a low-noise preamplifier, mixer, programmable gain amplifier (PGA) and lowpass filter. A variable gain low noise preamplifier topology is used to enable quasi-exponential time-gain control (TGC). The PGA enables digital selection of three gain values (15dB, 22dB and 25.5dB). The bandwidth of the lowpass filter is also selectable between 1.85MHz, 510kHz and 195kHz to allow for testing of both architectural frameworks. The entire AFE consumes 7.8 mW and occupies an area of 1.5×1.5 mm. In addition to the AFE, this thesis also presents the design of a pseudodifferential, log-domain multiplier-filter or “multer” which demodulates low-RF signals in the current-domain. This circuit targets high impedance transducers such as capacitive micromachined ultrasound transducers (CMUTs) and offers a 20dB improvement in dynamic range over the voltage-mode AFE. The bandwidth is also electronically tunable. The circuit was implemented in 0.35μm BiCMOS and was simulated in Cadence; however, no fabrication results were obtained for this circuit. B-mode images were obtained for both architectures. The quadrature SAB method yields a higher image SNR and 9% lower root mean squared error with respect to the RF-beamformed reference image than the compressive SAB method. Thus, while both architectures achieve a significant reduction in sampling rate, system complexity and area, the quadrature SAB method achieves better image quality. Future work may involve the addition of multiple receiver channels and the development of an integrated system-on-chip.