cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Talek: Private Group Messaging with Hidden Access Patterns
Creators: name: Cheng, Raymond
name: Scott, William
name: Masserova, Elisaweta
name: Zhang, Irene
name: Goyal, Vipul
name: Anderson, Thomas
name: Krishnamurthy, Arvind
name: Parno, Bryan
Publisher: name: arXiv
Year: 2020
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Talek is a private group messaging system that sends messages through potentially untrustworthy servers, while hiding both data content and the communication patterns among its users. Talek explores a new point in the design space of private messaging; it guarantees access sequence indistinguishability, which is among the strongest guarantees in the space, while assuming an anytrust threat model, which is only slightly weaker than the strongest threat model currently found in related work. Our results suggest that this is a pragmatic point in the design space, since it supports strong privacy and good performance: we demonstrate a 3-server Talek cluster that achieves throughput of 9,433 messages/second for 32,000 active users with 1.7-second end-to-end latency. To achieve its security goals without coordination between clients, Talek relies on information-theoretic private information retrieval. To achieve good performance and minimize server-side storage, Talek introduces new techniques and optimizations that may be of independent interest, e.g., a novel use of blocked cuckoo hashing and support for private notifications. The latter provide a private, efficient mechanism for users to learn, without polling, which logs have new messages.
Alternative Indicators of Farm Operators' Earnings
Creators: name: Strickland, Roger P.
name: Strickland, Roger P.
Publisher: name: Unknown
Year: 1982
Subjects: subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: Net farm income
subject: farmland appreciation
subject: agricultural tax preferences

description: Official U S Department of Agriculture (USDA)estimates of net farm income, measured in nominal dollars, have fluctuated widely over the past few years When measured in real dollars, net farm income has trended downward, in the aggregate, it approaches the levels of the thirties Far fewer farm operators share in the aggregate, resource efficiency is far greater now than in the thirties, and agriculture's financial management has become increasingly complex and sophisticated Therefore, USDA measures of net farm income may not be reliable indicators of farm earnings This article analyzes several alternative indicators of operator earnings
MOESM3 of 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial
Creators: name: Vijai Williams
name: Muralidharan Jayashree
name: Karthi Nallasamy
name: Dayal, Devi
name: Rawat, Amit
Publisher: name: figshare
Year: 2020
Subjects: Medicine
Developmental Biology
Computational Biology

description: Additional file 3: Figure S2. Hazard ratio for developing AKI.
Accounting for Cultural Dimensions in Estimating the Value of Coastal Zone Ecosystem Services using International Benefit Transfer
Creators: name: Hynes, Stephen
name: Norton, Daniel
name: Hanley, Nick
name: Hynes, Stephen
name: Norton, Daniel
name: Hanley, Nick
Publisher: name: Unknown
Year: 2012
Subjects: subject: Environmental Economics and Policy
subject: Research Methods/ Statistical Methods
subject: Resource /Energy Economics and Policy
subject: Non-market goods
subject: Benefit Transfer
subject: coastal ecosystem service

description: Values for non-market goods can be expected to be sensitive to variations in the cultural contexts of beneficiaries. However, little progress has been made to date in adapting benefit transfer procedures for cultural variations. Using information from a study that ranked 62 societies with respect to nine attributes of their cultures, we develop an index that is then used to re-weight multiple coastal ecosystem service value estimates. We examine whether these culturally-adjusted Benefit Transfer (BT) estimates are statistically different than simply transferring the income-adjusted mean transfer estimates for each coastal ecosystem service from international study sites to the policy site. We find that once differences in income levels have been accounted for, the differences in cultural dimensions between study and policy sites actually have little impact on the magnitude of our transfer estimates. This is not a surprising result given that the majority of the study site estimates are derived from countries that share many ethnic, linguistic and other cultural similarities to the policy site. However, benefit adjustments based on cultural factors could have a much higher impacts in settings different to that investigated here.
Non-adiabatic small polaron hopping in the n=3 Ruddlesden-Popper compound Ca4Mn3O10
Creators: name: Lago, J.
name: Battle, P. D.
name: Rosseinsky, M. J.
name: Coldea, A. I.
name: Singleton, J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Magnetotransport properties of the compound Ca4Mn3O10 are interpreted in terms of activated hopping of small magnetic polarons in the non-adiabatic regime. Polarons are most likely formed around Mn3+ sites created by oxygen substoichiometry. The application of an external field reduces the size of the magnetic contribution to the hopping barrier and thus produces an increase in the conductivity .We argue that the change in the effective activation energy around TN is due to the crossover to VRH conduction as antiferromagnetic order sets in.
description: 29 pages, 7 figures
Additional file 1 of 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial
Creators: name: Vijai Williams
name: Muralidharan Jayashree
name: Karthi Nallasamy
name: Dayal, Devi
name: Rawat, Amit
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 1: Table S1. Composition of different crystalloids. Table S2. Comparison of fluid balance of study groups. Table S3. Complications of DKA between study groups. Table S4. Incidence of AKI if GFR assumed as 90â€‰ml/min. Appendix. Clinical outcome definitions. Details of Data Safety Monitoring Board (DSMB).
SENSITIVITY OF PSYCHOPHYSICAL, ELECTROPHYSIOLOGICAL AND STRUCTURAL TESTS FOR DETECTION AND PROGRESSION MONITORING IN OCULAR HYPERTENSION AND GLAUCOMA
Creators: name: Raimundo, Miguel
name: Mateus, Catarina
name: Faria, Pedro
name: Oliveiros, Bárbara
name: Cardoso, João
name: Silva, João Filipe
name: Moura Pereira, José
name: Castelo-Branco, Miguel
Publisher: name: Revista Sociedade Portuguesa de Oftalmologia
Year: 2018

description: PURPOSE: To characterize early visual impairment of patients in the glaucoma spectrum, using psychophysical, electrophysiological and structural methods. METHODS: Cohort of 52 patients, 18 patients with ocular hypertension (HT), 15 glaucoma suspects (GS) and 19 with primary open-angle glaucoma (G), and 20 age-matched controls. Quantitative psychophysical methods were used to assess magno (FDT, Frequency Doubling Technology), parvo and koniocellular pathways (Cambridge Color Test), and RGC function was assessed by Pattern Electroretinogram. RGC axonal thickness was obtained using OCT. RESULTS: Reduced mean achromatic contrast sensitivity (p=0.0298) was found in patients with HT, as well as a reduced PERG N-95 wave amplitude (p=0.0499). Chromatic thresholds were significantly increased for protan, deutan and tritan axes (p<0.03) in these patients when compared to controls. At approximately 80% specificity, FDT showed only moderate sensitivity to detect early functional damage (superior nasal, 66% sensitivity). The pattern of disease progression decline is approximately linear for all tests, but more severe in OCT, RNFL thickness ( = 0.47). CONCLUSION: We found relative damage of magno, parvo and koniocellular retinocortical pathways beginning in ocular hypertension. FDT and CCT Protan performed well in detecting early damage in ocular hypertension, whereas longitudinal analysis using OCT for RFNL appeared to be the best to monitor the progression. The sensitivity of currently available tests is lower comparing with our previously reported novel psychophysical tools (sensitivity above 90% for 80% specificity). We believe early diagnosis in glaucoma is possible by exploiting visual pathways with a small degree of redundancy through high sensitivity functional tests.
description: Revista Sociedade Portuguesa de Oftalmologia, Vol. 42 N.º 1 (2018)
Enhanced Production of Neutron-Rich Rare Isotopes in Peripheral Collisions at Fermi Energies
Creators: name: Souliotis, G. A.
name: Veselsky, M.
name: Chubarian, G.
name: Trache, L.
name: Keksis, A.
name: Martin, E.
name: Shetty, D. V.
name: Yennello, S. J.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: A large enhancement in the production of neutron-rich projectile residues is observed in the reactions of a 25 MeV/nucleon 86Kr beam with the neutron rich 124Sn and 64Ni targets relative to the predictions of the EPAX parametrization of high-energy fragmentation, as well as relative to the reaction with the less neutron-rich 112Sn target. The data demonstrate the significant effect of the target neutron-to-proton ratio (N/Z) in peripheral collisions at Fermi energies. A hybrid model based on a deep-inelastic transfer code (DIT) followed by a statistical de-excitation code appears to account for part of the observed large cross sections. The DIT simulation indicates that the production of the neutron-rich nuclides in these reactions is associated with peripheral nucleon exchange. In such peripheral encounters, the neutron skins of the neutron-rich 124Sn and 64Ni target nuclei may play an important role. From a practical viewpoint, such reactions between massive neutron-rich nuclei offer a novel and attractive synthetic avenue to access extremely neutron-rich rare isotopes towards the neutron-drip line.
description: 4 pages, 3 figures, submitted to Phys. Rev. Lett
Magnetic properties of clusters of supracolloidal magnetic polymers with central attraction
Creators: name: Novak, Ekaterina V.
name: Zverev, Vladimir S.
name: Pyanzina, Elena S.
name: Sánchez, Pedro A.
name: Kantorovich, Sofia S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Supracolloidal magnetic polymers (SMPs) are structures made by crosslinking magnetic particles. In this work, using Langevin dynamics simulations, we study the zero-field magnetic properties of clusters formed in suspensions of SMPs with different topologies -- chains, rings, X and Y -- that interact via Stockmayer potential. We find that the presence of central attraction, resulting in the formation of large compact clusters, leads to a dramatic decrease of the suspension initial susceptibility, independently from SMP topology. However, the largest decrease corresponds to chain-like SMPs with strongly interacting particles. This is due to the higher rotational degrees of freedom of SMPs with such topology, which allows the particles to reorganise themselves inside the clusters in such a way that their magnetic moments form energetically advantageous vortex structures with negligible net magnetic moments.
description: International Conference on Magnetic Fluids - ICMF 2019
HYPERBARIC OXYGEN IN CRAO – OUR EXPERIENCE
Creators: name: Coelho, Pedro Aguiar
Publisher: name: Revista Sociedade Portuguesa de Oftalmologia
Year: 2018

description: ABSTRACT PURPOSE To report the visual outcomes of non-arteritic CRAO (NA-CRAO) patients submitted to hyperbaric oxygen therapy (HBOT) in our hospital. METHODS Retrospective anaylsis of patients with CRAO submitted to HBOT between 2010 and 2017. Only patients with non-transient NA-CRAO, absence of a patent cilioretinal artery and less of 24 hours of evolution were included. All patients were submitted to sessions of 90 minutes lenght with 100% oxygen at 2,4atm. Primary outcome was visual acuity change (logMar) pre and post treatment. Adverse effects from the treatment were registered. RESULTS Overall fourteen patients met the inclusion criteria, 57% males (n=8) and 43% females (n=6), with a median age of 68 years (min.41; max.92). VA at baseline was count-fingers (CF) or worse in 85,7% (n=12) of the patients. The median time between the symptoms onset and the beginning of the treatment was 7.0 hours (min.2; max.24h). The baseline and post treatment best-corrected visual acuity (BCVA) were 2,34±1,16 and 1,39±0,94 logMar respectively, which was statistical significant (p=0,007). VA gain was greater than 0.3 logMar in 71,4% of the patients. No serious adverse effects from HBOT were registered. One patient experienced mild ear barotrauma. CONCLUSIONS Patients with NA-CRAO experienced VA improvement after HBOT, although with important limitations. The implementation of strategies to reduce the time between the onset of symptoms and treatment could result in a higher functional gain.
description: Revista Sociedade Portuguesa de Oftalmologia, Vol. 42 N.º 2 (2018)
Additional file 11 of Protein phosphatase 1 regulatory subunit 15 A (PPP1R15A) promoted the progression of gastric cancer by activating cell autophagy under energy stress
Creators: name: Cui, Yingnan
name: Cao, Xueyuan
name: Zhang, Yangyu
name: Fu, Chenhao
name: Li, Dongming
name: Sun, Yuanlin
name: Zhang, Yuzheng
name: Xu, Tingshuang
name: Tsukamoto, Tetsuya
name: Cao, Donghui
name: Jiang, Jing
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Supplementary Material 11
Regional variations in choroidal thickness and retinal sensitivity in highly myopic patients
Creators: name: Silva, Rita
Publisher: name: Revista Sociedade Portuguesa de Oftalmologia
Year: 2018

description: Introduction: High myopia, defined by a spherical equivalent ≥ -6 diopters or an axial length ≥ 26 mm, can increase the risk of degenerative changes. The aim of this study was to correlate central choroidal thickness (CCT) and macular retinal sensitivity (MRS) in pseudophakic patients with high myopia. Material and Methods: Cross-sectional observational study in which high myopic eyes were included. CCT and MRS were analyzed by sector and correlated by semi-automatic segmentation. We used Topcon® DRI OCT and MP-3® Microperimeter for image acquisition. Results: 29 eyes from 20 patients were analyzed. CCT demonstrated increasing thickness from the nasal, inferior, central, temporal to the superior sector. MRS showed increasing sensibilities from the central sector, followed by the inferior, nasal, superior and temporal sector. The linear regression adjusted for gender and age verified correlation between the central MRS and the subfoveal CCT with p = 0.002 (R=0,551); between the central MRS and the mean CCT, in horizontal section with p = 0.006 (R=0.510) and in vertical section with p = 0.005 (R=0,513); between the MRS at the 6º inferior sector and the CCT at 1.5mm from the inferior sector with p = 0.018 (R=0.442), and finally, between the MRS at the 6º nasal sector and the CCT at 1.5mm from the nasal sector with p = 0.032 (R=0.407). Conclusion: After adjusting for gender and age, CCT is correlated with MRS in high myopic patients, and there was a statistically significant correlation (p<0.05) between the variables of interest in all sectors evaluated.
description: Revista Sociedade Portuguesa de Oftalmologia, Vol. 42 N.º 2 (2018)
Additional file 2 of 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial
Creators: name: Vijai Williams
name: Muralidharan Jayashree
name: Karthi Nallasamy
name: Dayal, Devi
name: Rawat, Amit
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Figure S1. Study work pathway.
A phase 2a, randomized, double-blind, placebo-controlled trial of the efficacy and safety of the oral gonadotropin-releasing hormone antagonist, ASP1707, in postmenopausal female patients with rheumatoid arthritis taking methotrexate
Creators: name: Takeuchi, Tsutomu
name: Tanaka, Yoshiya
name: Chieri Higashitani
name: Iwai, Megumi
name: Komatsu, Kanji
name: Akazawa, Rio
name: Lademacher, Christopher
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Many patients with rheumatoid arthritis (RA) are not able to achieve long-term disease remission. This phase 2a study (NCT02884635) evaluated the efficacy, safety, pharmacokinetics, and pharmacodynamics of the novel, oral, gonadotropin-releasing hormone antagonist, ASP1707, in combination with methotrexate (MTX) for treatment of RA. Postmenopausal women with RA who had been receiving MTX for ≥90 days were randomized to ASP1707 30 mg twice daily or placebo for 12 weeks. The primary endpoint was the American College of Rheumatology 20% improvement criteria (ACR20) response rate at week 12. Secondary endpoints included: ACR20, ACR50, and ACR70 response rates; disease activity score (DAS)28-CRP; DAS28-ESR; Tender or Swollen Joint Counts; and remission rates. Of 105 patients screened, 72 were randomized to ASP1707 30 mg twice daily (n = 37) or placebo (n = 35). ASP1707 did not improve ACR20, ACR50, or ACR70 response rates at any time point and did not improve any secondary efficacy endpoint. Plasma luteinizing hormone (LH) concentration decreased >90% in >90% of patients receiving ASP1707, with a rapid decrease to <1 IU/L at week 1 that remained stable throughout the treatment. In the current study, ASP1707 did not demonstrate a clinical benefit.
A Biome Portfolio Analysis (BPA) of Integrated Coastal Zone Management in the West of Ireland
Creators: name: Breen, Benjamin
name: Hynes, Stephen
name: Breen, Benjamin
name: Hynes, Stephen
Publisher: name: Unknown
Year: 2012
Subjects: subject: Environmental Economics and Policy
subject: Integrated Coastal Zone Management (ICZM)
subject: Biodiversity Portfolio Analysis (BPA)

description: EU policy geared towards the sustainable development of European coastal areas has incorporated Integrated Coastal Zone Management (ICZM) as one of its primary mechanisms to achieve its goal. However, critical shortcomings in the ICZM paradigm have emerged. In particular, incoherence in the European Commission’s ICZM principles with respect to local and strategic objectives remains an issue. Additionally, a lack of scientific certainty about environmental processes when determining the environmental pros and cons of alternative coastal-management decisions undermines environmentally protective decisions that may otherwise hinder local regional development. With these issues in mind, a Biodiversity Portfolio Analysis (BPA) is applied to Iarras Aithneach, a peninsula on the west coast of Ireland, to test its suitability as tool for ICZM. In addition, the paper uses the BPA methodology to explore the contrast between scientific/strategic and local attitudes towards the management of a coastal area of environmental importance. Pronounced differences between the two are found and the implications for both BPA and ICZM are discussed. The spatial and participatory nature of the BPA process and the explicit treatment of risk the framework exhibits suggest there is scope for it to become a useful tool for ICZM. It also has the potential to act as a routine way of quantifying the “attitude gap” between the scientific community and the local community when managing a unique coastal area.
Variação da pressão intraocular e da pressão de perfusão ocular com a hemodiálise em doentes de raça negra
Creators: name: Couceiro, Rita
Publisher: name: Revista Sociedade Portuguesa de Oftalmologia
Year: 2018

description: Resumo Objetivos: estudar a variação da pressão intraocular (PIO) e pressão de perfusão ocular (PPO) com a hemodiálise (HD), de forma a avaliar a contribuição destas alterações para o risco de glaucoma. Métodos: 32 olhos de 17 doentes de raça negra, com doença renal crónica terminal, foram submetidos a avaliação da PIO, pressão arterial (sistólica, diastólica e média), PPO (sistólica, diastólica e média) e peso corporal, antes (T1) e após (T2) uma sessão de hemodiálise (HD) de alto fluxo. Resultados: Em apenas 6 olhos se verificou uma diferença >4 mmHg na PIO entre T1 e T2 e a pressão arterial sistólica foi em média superior em T2. No entanto, estas diferenças não foram estatisticamente significativas, verificando-se o mesmo para as diferenças nos valores de pressão arterial diastólica e média e PPO (sistólica, diastólica e média) entre T1 e T2. O peso corporal em T1 foi significativamente superior ao peso corporal em T2 (t(16) = 0.09, p < 0.001). Em 9 doentes (52,9%) verificaram-se valores de PPO diastólicas ≤55 mmHg em T1 ou T2. Conclusões: As diferenças no peso corporal traduzem a efetiva diminuição da volémia após HD, sem que no entanto se tenham verificado variações significativas da pressão arterial, da PIO ou da PPO com a HD. Verificou-se, no entanto, que em algum momento do estudo, uma proporção considerável de doentes apresentou valores de PPO associados a um maior risco de glaucoma.
description: Revista Sociedade Portuguesa de Oftalmologia, Vol. 42 N.º 1 (2018)
Can contact potentials reliably predict stability of proteins?
Creators: name: Kahtun, Jainab
name: Khare, Sagar D.
name: Dokholyan, Nikolay V.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: The simplest approximation of interaction potential between amino-acids in proteins is the contact potential, which defines the effective free energy of a protein conformation by a set of amino acid contacts formed in this conformation. Finding a contact potential capable of predicting free energies of protein states across a variety of protein families will aid protein folding and engineering in silico on a computationally tractable time-scale. We test the ability of contact potentials to accurately and transferably (across various protein families) predict stability changes of proteins upon mutations. We develop a new methodology to determine the contact potentials in proteins from experimental measurements of changes in protein thermodynamic stabilities (ddG) upon mutations. We apply our methodology to derive sets of contact interaction parameters for a hierarchy of interaction models including solvation and multi-body contact parameters. We test how well our models reproduce experimental measurements by statistical tests. We evaluate the maximum accuracy of predictions obtained by using contact potentials and the correlation between parameters derived from different data-sets of experimental ddG values. We argue that it is impossible to reach experimental accuracy and derive fully transferable contact parameters using the contact models of potentials. However, contact parameters can yield reliable predictions of ddG for datasets of mutations confined to specific amino-acid positions in the sequence of a single protein.
description: 28 pages, 7 figs, 2 tables
Additional file 1 of Mitochondrial genome characterization of a Reticulinasus sp. (Argasidae: Ornithodorinae) parasitizing bats in Thailand
Creators: name: Tuangpermsub, Siwaporn
name: Arnuphapprasert, Apinya
name: Riana, Elizabeth
name: Ngamprasertwong, Thongchai
name: Kaewthamasorn, Morakot
Publisher: name: figshare
Year: 2025
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1. Table S1. Oligonucleotide primers used in this study for the amplification of short mitochondrial gene fragments. Table S2. Oligonucleotide primers used in this study for the amplification of long mitochondrial gene fragments of Reticulinasus ticks. Table S3. Sampling site details and bat captures, including GPS coordinates for each location. Table S4. Frequency of tick infestations on different bat species. Table S5. Intraspecific genetic distances of ticks obtained in this study, compared with reference sequences of the same species from the GenBank database. Table S6. Whole mitochondrial sequences retrieved from the GenBank database.
title: On the Impact of Empty Buckets on the Ferrite Cavity Control Loop Dynamics in High Intensity Hadron Synchrotrons
Creators: name: Stoica, D. Mihailescu
name: Domont-Yankulova, Dilyana
name: Klingbeil, Harald
name: Lens, Dieter Etienne Mia
Publisher: name: Joint Accelerator Conferences Website
Year: 2022

description: Due to technical reasons two of ten buckets have to stay empty in the planned SIS100 synchrotron at the GSI Helmholtzzentrum für Schwerionenforschung. The planned low level RF control systems consist of linear P and PI type controllers. These are responsible to maintain a desired phase and amplitude of the gap voltage. In addition the cavity is controlled to follow a prescribed resonance frequency ramp. In SIS100 the acceleration will be performed by ferrite cavities with comparatively small quality factors. Therefore, effects resulting from transient beam loading have to be expected. Influences due to empty buckets are analysed in the frequency domain and particle tracking simulations are carried out to estimate the effect on the overall system with particular consideration of emittance growth and particle loss.
Operating or not Operating at the Margin: Farmers Willingness to Adopt a Riparian Buffer Zone
Creators: name: Buckley, Cathal
name: Hynes, Stephen
name: Mechan, Sarah
name: Buckley, Cathal
name: Hynes, Stephen
name: Mechan, Sarah
Publisher: name: Unknown
Year: 2012
Subjects: subject: Environmental Economics and Policy
subject: Land Economics/Use
subject: Riparian buffer zone
subject: farmers
subject: ecosystem service
subject: willingness to accept

description: In the European Union, mitigation measures to abate diffuse pollution from agricultural land are implemented under the direction of the EU Nitrates and Water Framework Directives. As these measures are implemented in national policies, a review process will look at the efficacy of the measures with a view to recommending further measures as necessary. This study examines the willingness of farmers to adopt riparian buffer zones on agricultural land. A total of 247 farmers in 12 catchments in the Republic of Ireland were asked their opinion in relation to a proposal to install a 10 metre deep riparian buffer zone under a five year scheme and the analysis was based on principal components analysis, contingent valuation methodology and a Generalized Tobit Interval model. Results from this analysis indicated that famers’ willingness to supply a riparian buffer zone depended on a mix of economic, attitudinal and farm structural factors. A total of 53% of the sample indicated a negative preference for provision. Principle constraints to adoption include interference with production, nuisance effects and loss of production in small field systems. Of those willing to engage with supply, the mean willingness to accept based cost of provision for a 10 metre riparian buffer zone was estimated to be €1513 ha-1 per annum equivalent to €1.51 per linear metre of riparian area.
RASTREIO DE FATORES DE RISCO AMBLIOGÉNICOS – COMPARAÇÃO DE 2 MÉTODOS
Creators: name: Azenha, Cátia
name: Amaral, Joana
name: Machado, Marta
name: Sobral, Isa
name: Monteiro, Madalena
name: Castela, Rui
Publisher: name: Revista Sociedade Portuguesa de Oftalmologia
Year: 2018

description: Objetivo: Comparar duas modalidades de rastreio de fatores de risco ambliogénicos em crianças numa área urbana. Desenho: Estudo prospetivo. Participantes: crianças das pré-escolas e escolas básicas de uma área urbana. Materiais e métodos: Comparação de dois rastreios de fatores ambliogénicos independentes, de Abril a Setembro de 2014. O rastreio pré-escolar foi realizado com tecnologia de fotorrastreio. O rastreio escolar foi realizado de acordo com o protocolo validado usado nas consultas de rotina de Saúde Infantil e Juvenil dos Cuidados de Saúde Primários. Crianças com critérios de referenciação no rastreio pré-escolar eram convocadas a consulta de Oftalmologia Pediátrica, no rastreio escolar, era recomendada a referenciação. Resultados: Rastreio pré-escolar: 409 crianças rastreadas, destes 47 (11,6%) cumpriam critérios de referenciação. Das 25 que compareceram à consulta, todas apresentavam movimentos oculares externos, biomicroscopia e fundoscopia sem alterações significativas, 18 casos apresentavam fatores de risco ambliogénicos de causa refrativa, apresentando um valor preditivo positivo de 72%. Após tratamento todos melhoraram a acuidade visual. No rastreio escolar: das 664 crianças rastreadas, 102 (15,4%) tinham suspeita de patologia oftalmológica. Das 43 crianças avaliadas em consulta, 27 tinham um exame oftalmológico normal, 16 tinham alterações oftalmológicas, das quais 9 com potencial ambliogénicos ou ambliopia instalada, conferindo a este rastreio um valor preditivo positivo de 20,9 %. Conclusões: O fotorrastreio revelou ser superior à forma de rastreio vigente nas consultas de saúde infantil nos Cuidados de Saúde Primários Portugueses. Foi particularmente efetivo na identificação de fatores de risco ambliogénicos em crianças pré-literadas, com um valor preditivo positivo mais elevado.
description: Revista Sociedade Portuguesa de Oftalmologia, Vol. 42 N.º 2 (2018)
Reply to "Comment on `Rényi entropy yields artificial biases not in the data and incorrect updating due to the finite-size data' "
Creators: name: Oikonomou, Thomas
name: Bagci, G. Baris
Publisher: name: arXiv
Year: 2019
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We reply to the Comment by Jizba and Korbel [arXiv:1905.00729v1] by first pointing out that the Schur-concavity proposed by them falls short of identifying the correct intervals of normalization for the optimum probability distribution even though normalization is a must ingredient in the entropy maximization procedure. Secondly, their treatment of the subset independence axiom requires a modification of the Lagrange multipliers one begins with thereby rendering the optimization less trustworthy. We also explicitly demonstrate that the Rényi entropy violates the subset independence axiom and compare it with the Shannon entropy. Thirdly, the new composition rule offered by Jizba and Korbel are shown to yield probability distributions even without a need for the entropy maximization procedure at the expense of creating artificial bias in the data.
description: 4 pages, 2 figures, Accepted in Physical Review E (August 2019)
Ram pressure stripping and the formation of cold fronts
Creators: name: Heinz, S.
name: Churazov, E.
name: Forman, W.
name: Jones, C.
name: Briel, U. G.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Chandra and XMM-Newton observations of many clusters reveal sharp discontinuities in the surface brightness, which, unlike shocks, have lower gas temperature on the X-ray brighter side of the discontinuity. For that reason these features are called ``cold fronts''. It is believed that some cold fronts are formed when a subcluster merges with another cluster and the ram pressure of gas flowing outside the subcluster gives the contact discontinuity the characteristic curved shape. While some edges may not arise directly from mergers (e.g., A496, Dupke & White, 2003), this paper focuses on those which arise as contact discontinuities between a merging subcluster and the ambient cluster gas. We argue that the flow of gas past the merging subcluster induces slow motions inside the cloud. These motions transport gas from the central parts of the subcluster towards the interface. Since in a typical cluster or group (even an isothermal one) the entropy of the gas in the central regions is significantly lower than in the outer regions, the transport of the low entropy gas towards the interface and the associated adiabatic expansion makes the gas temperature immediately inside the interface lower than in any other place in the system, thus enhancing the temperature jump across the interface and making the ``tip'' of the contact discontinuity cool. We illustrate this picture with the XMM-Newton gas temperature map of the A3667 cluster.
description: 5 pages, 2 color figures, accepted for publication in MNRAS
MOESM2 of 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial
Creators: name: Vijai Williams
name: Muralidharan Jayashree
name: Karthi Nallasamy
name: Dayal, Devi
name: Rawat, Amit
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Figure S1. Study work pathway.
Neil Gehrels Swift Observatory studies of supersoft novae
Creators: name: Page, K. L.
name: Beardmore, A. P.
name: Osborne, J. P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The rapid response capabilities of the Neil Gehrels Swift Observatory, together with the daily planning of its observing schedule, make it an ideal mission for following novae in the X-ray and UV bands, particularly during their early phases of rapid evolution and throughout the supersoft source interval. Many novae, both classical and recurrent, have been extensively monitored by Swift throughout their supersoft phase and later decline. We collect here results from observations of novae with outbursts which occurred between the start of 2006 and the end of 2017.
description: 54 pages, 33 figure panels, 2 tables. To be published in a Special Issue of Advances in Space Research, entitled "Nova Eruptions, Cataclysmic Variables and Related Systems: observational vs theoretical challenges in the 2020 era", following COSPAR 2018
The Nature of SN 1961V
Creators: name: Chu, You-Hua
name: Gruendl, Robert A.
name: Stockdale, Christopher J.
name: Rupen, Michael P.
name: Cowan, John J.
name: Teare, Scott W.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The nature of SN 1961V has been uncertain. Its peculiar optical light curve and slow expansion velocity are similar to those of super-outbursts of luminous blue variables (LBVs), but its nonthermal radio spectral index and declining radio luminosity are consistent with decades-old supernovae (SNe). We have obtained Hubble Space Telescope STIS images and spectra of the stars in the vicinity of SN 1961V, and find Object 7 identified by Filippenko et al. to be the closest to the optical and radio positions of SN 1961V. Object 7 is the only point source detected in our STIS spectra and only its H-alpha emission is detected; it cannot be the SN or its remnant because of the absence of forbidden lines. While the H-alpha line profile of Object 7 is remarkably similar to that of eta Car, the blue color (similar to an A2Ib supergiant) and lack of appreciable variability are unlike known post-outburst LBVs. We have also obtained Very Long Baseline Array (VLBA) observations of SN 1961V at 18 cm. The non-detection of SN 1961V places a lower limit on the size of the radio-emitting region, 7.6 mas or 0.34 pc, which implies an average expansion velocity in excess of 4,400 km/s, much higher than the optical expansion velocity measured in 1961. We conclude the following: (1) A SN occurred in the vicinity of SN 1961V a few decades ago. (2) If the SN 1961V light maximum originates from a giant eruption of a massive star, Object 7 is the most probable candidate for the survivor, but its blue color and lack of significant variability are different from a post-outburst eta Car. (3) The radio SN and Object 7 could be physically associated with each other through a binary system. (4) Object 7 needs to be monitored to determine its nature and relationship to SN 1961V.
description: 16 pages, 3 figures, accepted by the Astronomical Journal for the 2004 May issue
MOESM1 of Implementation analysis of patient reported outcomes (PROs) in oncological routine care: an observational study protocol
Creators: name: Görlach, Mirja
name: Schrage, Theresa
name: Bokemeyer, Carsten
name: Kröger, Nicolaus
name: Müller, Volkmar
name: Petersen, Cordula
name: Betz, Christian
name: Krüll, Andreas
name: Schulz, Holger
name: Bleich, Christiane
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1: Standards for Reporting Implementation Studies: the StaRI checklist for completion
Efficacy and safety of canakinumab in systemic juvenile idiopathic arthritis: 48-week results from an open-label phase III study in Japanese patients
Creators: name: Nishimura, Kenichi
name: Ryoki Hara
name: Umebayashi, Hiroaki
name: Syuji Takei
name: Iwata, Naomi
name: Imagawa, Tomoyuki
name: Shimizu, Masaki
name: Tomiita, Minako
name: Seko, Noriko
name: Kitawaki, Tetsuji
name: Shumpei Yokota
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: To assess the efficacy and safety of canakinumab in Japanese patients with systemic juvenile idiopathic arthritis (sJIA). This was an open-label, single-arm active treatment study. sJIA patients, aged ≥2 to <20 years, were administered canakinumab 4 mg/kg every 4 weeks for ≤48 weeks. The co-primary endpoints were the proportion of patients who achieved an adapted American College of Rheumatology pediatric (ACR pedi) 30 criteria at week 8, and the proportion of patients who successfully tapered corticosteroids at week 28. Herein, the efficacy and safety results up to 48 weeks are reported. Of the 19 patients enrolled, 15 (78.9%) had previously used tocilizumab. All patients achieved ACR pedi 30 at week 8 and 73.7% (14/19) successfully tapered corticosteroids at week 28. At week 48, ACR pedi 50/70/90/100 responses were achieved by 100.0%/100.0%/87.5%/68.8% of patients. The most common adverse events (AEs) were infections (271.6 patient-years), 42.1% (8/19) patients had serious AEs. Two potential cases of macrophage activation syndrome were identified. No deaths were reported. Canakinumab was efficacious in Japanese patients with sJIA and was associated with substantial corticosteroid dose reduction in the majority of patients. The safety profile of canakinumab was consistent with that observed from previous studies. NCT02396212).
RESSONÂNCIA MAGNÉTICA FUNCIONAL NA AVALIAÇÃO DA NEUROADAPTAÇÃO APÓS IMPLANTE DE LENTE MULTIFOCAL
Creators: name: Costa, José F.
name: Rosa, Andreia
name: Miranda, Ângela
name: Almeida, Elisabete
name: Silva, Fátima
name: Castelo-Branco, Miguel
name: Murta, Joaquim
Publisher: name: Revista Sociedade Portuguesa de Oftalmologia
Year: 2018

description: OBJETIVO Avaliar, ao longo dos primeiros 6 meses pós-operatórios, o impacto cortical do deslumbramento num grupo de doentes implantados com lente intraocular multifocal através de ressonância magnética funcional (RMNf) MATERIAL E MÉTODOS Estudo prospetivo, comparativo, incluindo doentes (n=10) submetidos a implante bilateral de uma lente multifocal e um grupo de controlo não interventivo (n=10). Na 3ª semana e 6º mês pós-operatórios, foi realizado um exame oftalmológico complementado por RMNf. O estímulo funcional consistiu num padrão sinusoidal com contraste limiar (obtido através de psicofísica). Em metade dos ciclos de RMNf, o estímulo encontrava-se rodeado por uma fonte de luz para induzir deslumbramento. RESULTADOS Na 3ª semana pós-operatória, o deslumbramento induziu, no grupo de doentes, um atraso e diminuição do sinal BOLD máximo obtido com o estímulo sinusoidal (no córtex visual V1: βmax 0.03±0.04 e 0.10±0.03, com e sem deslumbramento, respetivamente). No grupo de controlo não se observaram alterações significativas. Ao 6º mês, observou-se um aumento de βmax (0.09 para 0.17) bem como do sinal BOLD total (área sob a curva 0.31 vs. 0.17 na 1ª visita, p<0.05). Estas alterações também foram observadas para as áreas visuais V2 e V3. O grupo de controlo apresentou um desempenho semelhante nas 2 visitas. CONCLUSÕES Os nossos resultados demonstram que é possível medir objetivamente o impacto do glare a nível cortical em indivíduos com lentes intraoculares multifocais e sugerem que mecanismos corticais são importantes para a melhoria das queixas visuais em doentes com lentes multifocais, confirmando, pela primeira vez, a ocorrência de fenómenos de neuroadaptação.
description: Revista Sociedade Portuguesa de Oftalmologia, Vol. 42 N.º 1 (2018)
Competition of fusion and quasi-fission in the reactions leading to production of the superheavy elements
Creators: name: Veselsky, M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The mechanism of fusion hindrance, an effect observed in the reactions of cold, warm and hot fusion leading to production of the superheavy elements, is investigated. A systematics of transfermium production cross sections is used to determine fusion probabilities. Mechanism of fusion hindrance is described as a competition of fusion and quasi-fission. Available evaporation residue cross sections in the superheavy region are reproduced satisfactorily. Analysis of the measured capture cross sections is performed and a sudden disappearance of the capture cross sections is observed at low fusion probabilities. A dependence of the fusion hindrance on the asymmetry of the projectile-target system is investigated using the available data. The most promising pathways for further experiments are suggested.
description: 8 pages, 7 figures, talk presented at 7th International School-Seminar on Heavy-Ion Physics, May 27 - June 1, 2002, Dubna, Russia
title: Semi-Autonomous Device for Visual Inspection of Vacuum Beamlines of Particle Accelerators
Creators: name: Schweizer, Nicolai
name: Pongrac, Ivan
Publisher: name: Joint Accelerator Conferences Website
Year: 2022

description: Due to the closed structure of ultra-high vacuum beamline systems, a visual inspection of the internal pipe is hardly feasible. For instance, when opening the accelerator vacuum system, an endoscope can be used to inspect the internals. However, this proves to be impractical in case of large, curved accelerator vacuum systems with complex geometries. It is more efficient to open the system only at one or two locations and to use a mobile semi-autonomous inspection device with optical imaging. A mobile robot is currently under development in our laboratory for the planned heavy ion synchrotron SIS100 at FAIR. A multitude of vacuum chamber types with different height levels as well as gaps must be traversed reliably by the robot. We present a modular wheel-based mobile robot prototype with joints between the modules which let the robot climb to different height levels by lifting the modules successively.
Additional file 1 of Arcyriaflavin A, a cyclin D1/CDK4 inhibitor, suppresses tumor growth, migration, and invasion of metastatic melanoma cells
Creators: name: Kim, Dokyeong
name: Park, Junseong
name: Kim, Yoon-Seob
name: Na, Okcho
name: Park, Minyoung
name: Zhang, Songzi
name: Cho, Sumin
name: Chung, Yeun-Jun
Publisher: name: figshare
Year: 2025
Subjects: Biochemistry
Medicine
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Developmental Biology
Cancer

description: Supplementary Material 1
Nematic Ordering of Rigid Rods in a Gravitational Field
Creators: name: Baulin, Vladimir A.
name: Khokhlov, Alexei R.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Space Physics (physics.space-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The isotropic-to-nematic transition in an athermal solution of long rigid rods subject to a gravitational (or centrifugal) field is theoretically considered in the Onsager approximation. The new feature emerging in the presence of gravity is a concentration gradient which coupled with the nematic ordering. For rodlike molecules this effect becomes noticeable at centrifugal acceleration g ~ 10^3--10^4 m/s^2, while for biological rodlike objects, such as tobacco mosaic virus, TMV, the effect is important even for normal gravitational acceleration conditions. Rods are concentrated near the bottom of the vessel which sometimes leads to gravity induced nematic ordering. The concentration range corresponding to phase separation increases with increasing g. In the region of phase separation the local rod concentration, as well as the order parameter, follow a step function with height.
description: Full article http://prola.aps.org/abstract/PRE/v60/i3/p2973_1
Roles of electron correlation effects for accurate determination of $g_j$ factors of low-lying states of $^{113}$Cd$^+$ and their applications to atomic clock
Creators: name: Han, J. Z.
name: Yu, Y. M.
name: Sahoo, B. K.
name: Zhang, J. W.
name: Wang, L. J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We investigate roles of electron correlation effects in the determination of $g_j$ factors of the $ns~^2S_{1/2}$ ($n$=5,6,7), $np~^2P_{1/2,3/2}$ ($n$=5,6), $5d~^2D_{3/2,5/2}$, and $4f~^2F_{5/2,7/2}$ states of the singly ionized cadmium (Cd$^+$) ion. Single and double excited configurations along with important valence triple excited configurations through relativistic coupled-cluster (RCC) theory are taken into account for incorporating electron correlation effects in our calculations. We find significant contributions from the triples to the lower $S$ and $P$ states for attaining high accuracy results. The contributions of Breit interaction and lower-order quantum electrodynamics effects, such as vacuum polarization and self-energy corrections, are also estimated using the RCC theory and are quoted explicitly. In addition, we present energies of the aforementioned states from our calculations and compare them with the experimental results to validate $g_j$ values. Using the $g_j$ factor of the ground state, systematical shift due to the Zeeman effect in the microwave clock frequency of the $|5s~^2S_{1/2}, F=0,m_F=0 \rangle \leftrightarrow |5s~^2S_{1/2}, F=1,m_F=0 \rangle$ transition in $^{113}$Cd$^+$ ion has been estimated.