cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Detection and quantitation of HPV in anogenital and oral tissues and fluids of HIV-positive individuals by real-time PCR
Creators: name: Couch, Marion
name: Webster-Cyriaque, Jennifer
name: Deal, Allison M
name: Seaman, William T
name: Andrews, Elizabeth
Publisher: name: BioMed Central Ltd
Year: 2010

description: Human papillomaviruses (HPV) remain a serious world
health problem due to their association with anogenital
and oral cancers and warts. While over 100 HPV types
have been identified, only a subset is associated with
malignancy. HPV16 and 18 are the most common oncogenic
types, while HPV6 and 11 are the most common
types responsible for anogenital warts. These four types
cause up to 90% of HPV-associated disease. While other
quantitative PCR (qPCR) assays can be used to detect
oncogenic HPV, there is no single tube assay that distinguishes
the most frequent oncogenic types and the most
common types found in warts. A qPCR assay was developed
that allowed for detection and quantitation of
these 4 HPV types.
Response of an invasive aquatic crustacean to the fish toxicant rotenone
Creators: name: Lepak, Jesse M.
name: Pate, William M.
name: Cadmus, Pete
name: Hansen, Adam G.
name: Gallaher, Kiah D.
name: Silver, Douglas B.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Lepak JM, Pate WM, Cadmus P, Hansen AG, Gallaher KD, Silver DB. 2024. Response of an invasive aquatic crustacean to the fish toxicant rotenone. Lake Reserv Manage. 40:317–324 Fisheries managers have used the piscicide rotenone for invasive fish control and other management objectives for decades, yet the effects of rotenone on some aquatic species are not well understood. We tested the effects of rotenone on an invasive crustacean Mysis diluviana that can have deleterious effects on aquatic food webs (e.g., zooplankton communities) and ultimately some native and sport fishes. The median 50% lethal concentration (LC50) was assessed for M. diluviana at 24, 48, 96, and 192 h using active rotenone concentrations from 0 to 4111 ppb. At 24 and 48 h, LC50s were not reached, and at 96 and 192 h, LC50s were estimated at 4853 (95% CI = 1280–8426) and 668 (385–952) ppb, respectively, above (∼25-fold and 3-fold) recommended rotenone application concentrations to control fishes. Our results suggest that rotenone concentrations and exposure times used for controlling invasive fishes are likely to have limited to no effect on invasive M. diluviana populations. Thus, if M. diluviana control is a management objective, rotenone applications targeting invasive fishes are unlikely to contribute to this objective, and other methods should be considered that take advantage of potential vulnerabilities of M. diluviana, like temperature and light sensitivity.
ЙЎЛ ҲАРАКАТИ ХАВФСИЗЛИГИ РИВОЖЛАНИШ КОНЦЕПЦИЯСИНИНГ ИСТИҚБОЛЛАРИ
Creators: name: Н. У. Аллаяров
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: Йўл ҳаракати
хавфсизлик
механик
транспорт
йўл ҳаракати қатнашчилари.

description: Мазкур мақолада йўл ҳаракати хавфсизлигини таъминлаш соҳасида амалга оширилаѐтган ислоҳотлардан кўзланган асосий мақсад ҳам аввало йўл ҳаракати қатнашчиларининг ҳаѐти ва соғлиғини муҳофаза қилишнинг қонуний кафолатларини мустаҳкамлашдир. Бу борада йўл ҳаракати хавфсизлигини таъминлашнинг янгича ва замовий механизмларни ишлаб чиқиш, ушбу фаолият йўналишлари бўйича илмий тадқиқотларни амалга ошириш, муаммоларни тадқиқ этиш ва бартараф этиш бўйича самарали методларини ишлаб чиқиш муҳим аҳамияти ҳақида сўз юритилган
Sample Size Guidance for External Randomised Controlled Pilot Trials: A Protocol for a Methodological Systematic Review
Creators: name: Eddy, Saskia
name: Parker, Kitty
name: Robinson, Clare
name: Eldridge, Sandra
name: Lancaster, Gillian
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Clinical Trials
subject: Statistics and Probability
subject: Other Statistics and Probability
subject: Physical Sciences and Mathematics
subject: Biostatistics
subject: Vital and Health Statistics
subject: clinical trials
subject: feasibility
subject: feasibility study
subject: feasibility trial
subject: methodological systematic review
subject: methodology
subject: PAFS
subject: pilot
subject: pilot study
subject: pilot trial
subject: sample size
subject: study
subject: systematic review
subject: trial

description: This methodological systematic review is part of a larger programme of work to provide some further guidance to help health researchers choose an appropriate sample size for their external randomised controlled pilot trials. This systematic review will inform the first round of a modified Delphi study designed to provide clarity about the sample size of pilot trials. This methodological systematic review will identify and describe the sample size justifications for external randomised controlled pilot trials. This methodological systematic review will help health researchers by summarising the available sample size justifications. Currently the pilot trial sample size justifications are published in various journals. The guidance produced as a result of the modified Delphi study will help health researchers choose appropriate sample sizes for their external pilot trials
Are You for Real? Perceptions of Authenticity are Systematically Biased and Not Accurate
Creators: name: Bailey, Erica
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This registered project contains the codebook, survey materials, data, and code for each study in the paper titled 'Are You for Real? Perceptions of Authenticity are Systematically Biased and Not Accurate' by Erica Bailey and Aharon Levy.
Origin of the mass splitting of elliptic anisotropy in a multiphase transport model
Creators: name: Li, Hanlin
name: He, Liang
name: Lin, Zi-Wei
name: Molnar, Denes
name: Wang, Fuqiang
name: Xie, Wei
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The mass splitting of elliptic anisotropy ($v_2$) at low transverse momentum is considered as a hallmark of hydrodynamic collective flow. We investigate a multiphase transport (AMPT) model where the $v_2$ is mainly generated by an anisotropic escape mechanism, not of the hydrodynamic flow nature, and where mass splitting is also observed. We demonstrate that the $v_2$ mass splitting in AMPT is small right after hadronization (especially when resonance decays are included); the mass splitting mainly comes from hadronic rescatterings, even though their contribution to the overall charged hadron $v_2$ is small. These findings are qualitatively the same as those from hybrid models that combine hydrodynamics with a hadron cascade. We further show that there is no qualitative difference between heavy ion collisions and small system collisions. Our results indicate that the $v_2$ mass splitting is not a unique signature of hydrodynamic collective flow and thus cannot distinguish whether the elliptic flow is generated mainly from hydrodynamics or the anisotropic parton escape.
description: 5 pages, 4 figures
Barriers to women's participation in inter-conceptional care: a cross-sectional analysis
Creators: name: Amamoo, M Ahinee
name: Rowley, Diane
name: Hogan, Vijaya
Publisher: name: BioMed Central Ltd
Year: 2012

description: Abstract Background We describe participation rates in a special interconceptional care program that addressed all commonly known barriers to care, and identify predictors of the observed levels of participation in this preventive care service. Methods A secondary analysis of data from women in the intervention arm of an interconceptional care clinical trial in Philadelphia (n = 442). Gelberg-Andersen Behavioral Model for Vulnerable Populations to Health Services (herein called Andersen model) was used as a theoretical base. We used a multinomial logit model to analyze the factors influencing women's level of participation in this enhanced interconceptional care program. Results Although common barriers were addressed, there was variable participation in the interconceptional interventions. The Andersen model did not explain the variation in interconceptional care participation (Wald ch sq = 49, p = 0.45). Enabling factors (p = 0.058), older maternal age (p = 0.03) and smoking (p = < 0.0001) were independently associated with participation. Conclusions Actively removing common barriers to care does not guarantee the long-term and consistent participation of vulnerable women in preventive care. There are unknown factors beyond known barriers that affect participation in interconceptional care. New paradigms are needed to identify the additional factors that serve as barriers to participation in preventive care for vulnerable women.
Does exercise for chronic low back pain meet physical activity guidelines? Protocol for a secondary analysis of a Cochrane Review
Creators: name: Jones, Matthew
name: Gibbs, Mitchell
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Sports Sciences
subject: Physiotherapy
subject: Medicine and Health Sciences
subject: Rehabilitation and Therapy
subject: Physical Therapy

description: This is a preregistration for a secondary analysis of a Cochrane Review of exercise for chronic low back pain. We will investigate the proportion of studies in the Cochrane Review that meet the World Health Organisation physical activity guidelines.
Trichoderma tenue W. T. Qin & W. Y. Zhuang HMAS 2017, sp. nov.
Creators: name: Qin, Wen-Tao
name: Zhuang, Wen-Ying
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Sordariomycetes
Hypocreales
Hypocreaceae
Trichoderma
Trichoderma tenue

description: Trichoderma tenue W.T. Qin & W.Y. Zhuang, sp. nov. FIGURE 7
 Etymology:— The specific epithet refers to the slender phialides.
 MycoBank: MB 816634
 Type: — CHINA. HUBEI: Shennongjia, Tianziya, 2000 m, on rotten twigs, 16 Sep 2014, W. T. Qin, Z.Q. Zeng, H.D. Zheng & K. Chen 9709 (holotype HMAS 273785).
Colony radius on CMD 22–27 mm after 72 h, mycelium covering the plate after 8–9 d at 25 C. Colony dense, circular, aerial hyphae abundant, conidiation noted after 24 h, in whitish granules or pustules, eventually becoming light green. Conidiophores trichoderma- to verticillium-like with phialides solitary or in whorls of 2–5 arising from the main axis. Phialides lageniform or subulate, commonly slender, (6.5–)7–14 × 1.4–2 μm, l/w (3.3–)4.5–6(–7), 1.2–1.8 μm wide at the base (n = 50). Conidia light green, globose or subglobose, smooth, 2.5–3.5 × 2.5–2.8 μm, l/ w 1.0 –1.3(–1.4) (n = 50). No chlamydospores observed. No distinct odor, no diffusing pigment observed.
Colony radius on PDA 24–25 mm after 72 h, mycelium covering the plate after 8 d at 25 C. Colony whitish, dense, with thin, diffuse margin, indistinctly and irregularly zonate. Aerial hyphae richly branched, radial towards margin with surface downy, farinose to floccose. No distinct odor; no diffusing pigment observed.
Colony radius on SNA 15–17 mm after 72 h, mycelium covering the plate after 12 d at 25 C. Colony thin, zonate, aerial hyphae numerous, farinose to floccose, conidiation formed after 24 h on them. No distinct odor; no diffusing pigment observed.
 Notes:— Trichoderma tenue is associated with T. priciliae and T. rufobrunneum based on the sequence data (Figure 1). Trichoderma priscilae is fast-growing [CMD 57–62 mm, PDA 40–43 mm, SNA 52–54 mm], and forms pachybasium-like conidiophores (Jaklitsch & Voglmayr 2015). Trichoderma rufobrunneum is similar to T. tenue in verticillium-like conidiophores, but differs conspicuously by forming compact pulvinate to hemispherical pustules in culture, fast-growth [CMD 40–50 mm, PDA 31–35 mm, SNA 21–25 mm], shorter phialides [(6–)8–10(–12.5) × 2–3 μm], and larger conidia [(2.5–)3–4(–5.5) × 2.5–3(–4) μm] (Zhu & Zhuang 2015).
description: Published as part of Qin, Wen-Tao & Zhuang, Wen-Ying, 2017, Seven new species of Trichoderma (Hypocreales) in the Harzianum and Strictipile clades, pp. 121-139 in Phytotaxa 305 (3) on page 133, DOI: 10.11646/phytotaxa.305.3.1, http://zenodo.org/record/13694923
Predicting populist and technocratic attitudes & choices: A cross-country survey study
Creators: name: Fernandez-Vazquez, Pablo
name: Lavezzolo, Sebastián
name: Ramiro, Luis
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Political Science
subject: FOS: Political science
subject: Social and Behavioral Sciences
subject: cultural anxiety
subject: economic hardship
subject: populism
subject: survey experiment
subject: technocracy

description: full pre-analysis plan
Performance analysis of parallel gravitational $N$-body codes on large GPU cluster
Creators: name: Huang, Siyi
name: Spurzem, Rainer
name: Berczik, Peter
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We compare the performance of two very different parallel gravitational $N$-body codes for astrophysical simulations on large GPU clusters, both pioneer in their own fields as well as in certain mutual scales - NBODY6++ and Bonsai. We carry out the benchmark of the two codes by analyzing their performance, accuracy and efficiency through the modeling of structure decomposition and timing measurements. We find that both codes are heavily optimized to leverage the computational potential of GPUs as their performance has approached half of the maximum single precision performance of the underlying GPU cards. With such performance we predict that a speed-up of $200-300$ can be achieved when up to 1k processors and GPUs are employed simultaneously. We discuss the quantitative information about comparisons of two codes, finding that in the same cases Bonsai adopts larger time steps as well as relative energy errors than NBODY6++, typically ranging from $10-50$ times larger, depending on the chosen parameters of the codes. While the two codes are built for different astrophysical applications, in specified conditions they may overlap in performance at certain physical scale, and thus allowing the user to choose from either one with finetuned parameters accordingly.
description: 15 pages, 7 figures, 3 tables, accepted for publication in Research in Astronomy and Astrophysics (RAA)
The state of the drugs problem in Europe
Annual report 2005
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Tübingen
Year: 2005
Subjects: subject: Europäische Union , Drogenmissbrauch , Statistik
subject: 360
subject: 610

description: The report on the state of the drugs problem in Europe presents the EMCDDA's yearly overview of the drug phenomenon. This is an essential reference book for policy-makers, specialists and practitioners in the drugs field or indeed anyone seeking the latest findings on drugs in Europe. Published every autumn, the report contains non-confidential data supported by an extensive range of figures.
Estimating the Prevalence of Problem Drug Use in Europe
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Tübingen
Year: 1997
Subjects: subject: Europa , Drogenmissbrauch , Schätzung
subject: 360
subject: 610

description: This is a landmark publication on prevalence estimation theory and method in the European Union. The monograph – the result of collaboration between 30 scientific authors – explores the relationship between epidemiological work on the estimation of drug problems and the development of drug policy and strategy. The strengths and weaknesses of the most commonly used estimation techniques – such as case finding, capture–recapture, multiplier and nomination – are uncovered in the volume, as are the virtues of combining and comparing different methods in the estimation process. The monograph underlines the need to improve the quality of data on which prevalence estimates depend, and to complement these estimates with qualitative studies exploring other aspects of the drug situation beyond the statistics.
RADAR: Building a FAIR and community tailored Research Data Repository
Creators: name: Bach, Felix
name: Soltau, Kerstin
Publisher: name: Zenodo
Year: 2023
Subjects: Research Data Management
Research Data Repository
Forschungsdatenmanagement
Forschungsdaten
FDM
Data Publication
FAIR Principles
FAIR Signposting
Metadata
NFDI

description: The research data repository RADAR supports the secure management, archiving, publication and dissemination of digital research data from completed scientific studies and projects. Developed as a collaborative project funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) (2013-2016), the system is operated by FIZ Karlsruhe-Leibniz Institute for Information Infrastructure. Since its launch in 2017, FIZ Karlsruhe has witnessed significant changes in the landscape of research data repositories and the evolving needs of researchers, research communities and institutions. The presentation gives an overview about RADAR´s feature set and shows how FIZ Karlsruhe has responded to these dynamic changes until now and will respond in the future.

 Moving away from the previous only focus on a discipline-independent cloud service, FIZ Karlsruhe for example introduced additional operating variants (e. g. RADAR Local) and community-specific publication service offerings, in particular in the context of the National Research Data Infrastructure (NFDI): RADAR4Chem and RADAR4Culture. Besides the expansion of RADAR´s functional scope, FIZ Karlsruhe also works on the system's support for the FAIR principles, the concepts of FAIR Digital Objects (FDO) and Schema.org. These slides were presented at CoRDI Conference 2023 and the corresponding abstract is available at https://doi.org/10.52825/cordi.v1i.295
High-Efficiency Cooper-Pair Splitter in Quantum Anomalous Hall Insulator Proximity-Coupled with Superconductor
Creators: name: Zhang, Ying-Tao
name: Deng, Xinzhou
name: Sun, Qing-Feng
name: Qiao, Zhenhua
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The quantum entanglement between two qubits is crucial for applications in the quantum communication. After the entanglement of photons was experimentally realized, much effort has been taken to exploit the entangled electrons in solid-state systems. Here, we propose a Cooper-pair splitter, which can generate spatially-separated but entangled electrons, in a quantum anomalous Hall insulator proximity-coupled with a superconductor. After coupling with a superconductor, the chiral edge states of the quantum anomalous Hall insulator can still survive, making the backscattering impossible. Thus, the local Andreev reflection becomes vanishing, while the crossed Andreev reflection becomes dominant in the scattering process. This indicates that our device can serve as an extremely high-efficiency Cooper-pair splitter. Furthermore, because of the chiral characteristic, our Cooper-pair splitter is robust against disorders and can work in a wide range of system parameters. Particularly, it can still function even if the system length exceeds the superconducting coherence length.
Response of SI cortex to ipsilateral, contralateral and bilateral flutter stimulation in the cat
Creators: name: Tommerdahl, Mark Allen
name: Simons, Stephen B
name: Whitsel, Barry
name: Chiu, Joannellyn S
name: Favorov, Oleg
Publisher: name: BioMed Central Ltd
Year: 2005

description: Abstract Background While SII cortex is considered to be the first cortical stage of the pathway that integrates tactile information arising from both sides of the body, SI cortex is generally not considered as a region in which neuronal response is modulated by simultaneous stimulation of bilateral (and mirror-image) skin sites. Results Optical intrinsic signal imaging was used to evaluate the response of SI and SII in the same hemisphere to 25 Hz sinusoidal vertical skin displacement stimulation ("skin flutter") applied contralaterally, ipsilaterally, and bilaterally (simultaneously) to the central pads of the forepaws. A localized increase in absorbance in both SI and SII occurred in response to both contralateral and bilateral flutter stimulation. Ipsilateral flutter stimulation evoked a localized increase in absorbance in SII, but little or no change in SI absorbance. In the forepaw representational region of SI, however, bilateral stimulation of the central pads evoked a response substantially smaller (approximately 30–35% smaller) than the response to flutter stimulation of the contralateral central pad. Conclusion The finding that the response of SI cortex to bilateral central pad flutter stimulation is substantially smaller than the response evoked by a contralateral flutter stimulus, together with the recently published observation that a region located posteriorly in SII responds with a substantially larger response to a bilateral flutter stimulus than the response evoked from the contralateral central pad, lead us to propose that the SI activity evoked by contralateral skin stimulation is suppressed/inhibited (via corticocortical connections between SII and SI in the same hemisphere) by the activity a simultaneous ipsilateral skin stimulus evokes in posterior SII.
Reflections on planning professionalism
Creators: name: Seasons, Mark
Publisher: name: Vancouver Island University - Royal Roads University
Year: 1999
Subjects: subject: Planners--Practice

description: A commentary on Dr. Leonie Sandercock's article, A portrait of postmodern planning: Anti-hero and/or passionate pilgrim, which is also included in this issue of Plan Canada.
description: https://viurrspace.ca/bitstream/handle/10613/6050/Article004.pdf?sequence=3
ҚАДИМГИ ҲИНД ФАЛСАФАВИЙ МАНБААЛАРИ ВА ТАДҚИҚОТ УСЛУБЛАРИ
Creators: name: Тимур Абдувалиевич Мадалимов
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: ведачилик
Упанишадлар
пали
самхит
веданта

description: Мақолада қадимги Ҳиндистонда мавжуд бўлган манбаалар ва тадқиқотлар қисман ўрганилган. Асосан Ведачилик ва унинг китоблари таҳлил қилинган.
Towards collaboration between planning practitioners and academics
Creators: name: Witty, David R.
Publisher: name: Vancouver Island University - Royal Roads University
Year: 1999
Subjects: subject: Planners--Practice
subject: Planners--Education (Higher)

description: A commentary on the appendix of Dr. Leonie Sandercock's book, Towards cosmopolis: Planning for multicultural cities (Chichester: Wiley, 1998).
description: https://viurrspace.ca/bitstream/handle/10613/6051/Article003.pdf?sequence=3
Level of helium enhancement among M3's horizontal-branch stars
Creators: name: Valcarce, A. A. R.
name: Catelan, M.
name: Alonso-García, J.
name: Ramos, R. Contreras
name: Alves, S.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: (Abridged) The color and luminosity distribution of horizontal branch (HB) stars in globular clusters are sensitive probes of their original helium abundances. However, recent analyses based on visual and near-ultraviolet (UV) CMDs have provided conflicting results. To clarify the situation, we address the optimum ranges of applicability (in terms of the $T_{eff}$ range covered by the HB stars) for visual and near-UV CMDs, as far as application of this HB $Y$ test goes. We consider both Stromgren and Hubble Space Telescope (HST) bandpasses. Our results indicate that the distributions of HB stars in the y vs (b-y) plane can be a reliable indicator of the He content in cool blue HB (BHB) stars, particularly when a differential comparison between blue and red HB stars is carried out in the range $T_{eff}<8300$K. Conversely, we demonstrate that CMDs using the F336W filter have a much less straightforward interpretation at the cool end of the BHB, as the distributions of HB stars in the F336W vs (F336W-F555W) plane are affected by a triple degeneracy effect. In other words, the position of an HB star is exactly the same, for a given chemical composition, for multiple combinations of the parameters $Y$, $M_{HB}$, and age along the HB evolutionary track. Other HST UV filters do not appear to be as severely affected by this degeneracy effect, to which visual bandpasses are also immune. We do find, on the other hand, that such near-UV CMDs can be extremely useful for the hottest stars along the cool BHB end. Based on a reanalysis of the distribution of HB stars in the y vs (b-y) plane, we find that the coolest among the BHB stars in M3 are likely enhanced in helium by $ΔY\approx 0.01$, compared with the red HB stars in the same cluster. Using near-UV HST photometry we find evidence of a progressive increase in $Y$ with increasing temperature, reaching $ΔY=0.02$ at $T_{eff}=10900$K.
description: Accepted to be published in A&A. 13 pages, 8 figures, v2
Rummaging in the compost
Creators: name: Davidson, Gary
Publisher: name: Vancouver Island University - Royal Roads University
Year: 1999
Subjects: subject: Planning--Practice

description: A commentary on the appendix of Dr. Leonie Sandercock's book, Towards cosmopolis: Planning for multicultural cities (Chichester: Wiley, 1998).
description: https://viurrspace.ca/bitstream/handle/10613/6052/Article002.pdf?sequence=3
A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy
Creators: name: Tucker, Joseph
name: Li, Trudy
name: Cohen, Myron
name: Seña, Arlene C
Publisher: name: BioMed Central
Year: 2015

description: Abstract Background Syphilis remains a global public health threat and can lead to severe complications. In addition to resolution of clinical manifestations, a reduction in nontreponemal antibody titers after treatment is regarded as “proof of cure.” However, some patients manifest < 4-fold decline (“serological non-response”) or persistently positive nontreponemal titers despite an appropriate decline (“serofast”) that may represent treatment failure, reinfection, or a benign immune response. To delineate these treatment phenomena, we conducted a systematic review of the literature regarding serological outcomes and associated factors among HIV-infected and -uninfected subjects. Methods Six databases (PubMed, Embase, CINAHL, Web of Science, Scopus, and BIOSIS) were searched with no date restrictions. Relevant articles that evaluated serological treatment responses and correlates of serological cure (≥ four-fold decline in nontreponemal titers) were included. Results We identified 1693 reports in the literature, of which 20 studies met selection criteria. The median proportion of patients who had serological non-response was 12.1 % overall (interquartile range, 4.9–25.6), but varied depending on the time points after therapy. The serofast proportion could only be estimated from 2 studies, which ranged from 35.2–44.4 %. Serological cure was primarily associated with younger age, higher baseline nontreponemal titers, and earlier syphilis stage. The relationship between serological cure and HIV status was inconsistent; among HIV-infected patients, CD4 count and HIV viral load was not associated with serological cure. Conclusions Serological non-response and the serofast state are common syphilis treatment outcomes, highlighting the importance of determining the immunological and clinical significance of persistent nontreponemal antibody titers after therapy.
Fostering student nurses’ evaluative judgement in clinical practice education: a systematic review
Creators: name: Henderson, Bridget
name: Lewis, Lucy
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Education
subject: Higher Education
subject: Nursing
subject: FOS: Health sciences

description: Systematic review Authors Bridget Henderson, Lucy Chipchase, Lucy Lewis, Fleur Golder
The role of mirroring and mentalizing networks in mediating action intentions in autism
Creators: name: Klinger, Mark
name: Klinger, Laura
Publisher: name: BioMed Central Ltd
Year: 2014

description: Abstract Background The ability to interpret agents’ intent from their actions is a vital skill in successful social interaction. However, individuals with autism spectrum disorders (ASD) have been found to have difficulty in attributing intentions to others. The present study investigated the neural mechanisms of inferring intentions from actions in individuals with ASD. Methods Functional magnetic resonance imaging (fMRI) data were acquired from 21 high-functioning young adults with ASD and 22 typically developing (TD) control participants, while making judgments about the means (how an action is performed) and intention (why an action is performed) of a model’s actions. Results Across both groups of participants, the middle and superior temporal cortex, extending to temporoparietal junction, and posterior cingulate cortex, responded significantly to inferring the intent of an action, while inferior parietal lobule and occipital cortices were active for judgments about the means of an action. Participants with ASD had significantly reduced activation in calcarine sulcus and significantly increased activation in left inferior frontal gyrus, compared to TD peers, while attending to the intentions of actions. Also, ASD participants had weaker functional connectivity between frontal and posterior temporal regions while processing intentions. Conclusions These results suggest that processing actions and intentions may not be mutually exclusive, with reliance on mirroring and mentalizing mechanisms mediating action understanding. Overall, inferring information about others’ actions involves activation of the mirror neuron system and theory-of-mind regions, and this activation (and the synchrony between activated brain regions) appears altered in young adults with ASD.
A portrait of postmodern planning: Anti-hero and/or passionate pilgrim?
Creators: name: Sandercock, Leonie
Publisher: name: Vancouver Island University - Royal Roads University
Year: 1999
Subjects: subject: City planning
subject: Planners--Practice

description: Many commentators have argued that the modernist planning project has failed. This paper proposes a way forward for the profession, offering a portrait of the postmodern planner as a passionate pilgrim, a tireless seeker after social, environmental and cultural justice in the planning of human settlements. I outline five critical elements of the shift from a modernist to a postmodern paradigm; I ask what, or whom, might inspire our vision of planning for the twenty-first century; and I sketch some of the qualities, or literacies (technical, multicultural, ecological, and design-based), that the passionate pilgrim will need for the journey into the next century.
description: De nombreux observateurs ont prétendu que la période moderniste de l'urbanisme était un échec. Cet article propose une perspective d'avenir en traçant un portrait de l'urbaniste postmoderne. Il le présente comme un pèlerin passionné poursuivant sa quête inlassable d'une justice sociale, environnementale et culturelle dans l'aménagement des milieux de vie. On y expose cinq éléments marquants du passage du modernisme au postmodernisme ; l'auteur cherche à savoir de quoi ou de qui devrait surgir notre vision de l'urbanisme du 21ème siècle et y ébauche quelques-unes des aptitudes ou des connaissances (technique, cultures, écologie et design) qui seront nécessaires à cet infatigable pèlerin pour poursuivre sa route dans le prochain siècle.
description: Abstract in English and French; text in English.
description: https://viurrspace.ca/bitstream/handle/10613/6053/Article001.pdf?sequence=3
Reporte del Dialogo Deliberativo: Verificación y validación externa de la Ruta Integral de Atención en Salud RIAS para amputaciones de miembro inferior por causas traumáticas y neurovasculares.
Creators: name: Velasquez, Juan
name: Borrero, Ana
name: Agudelo, Luz
name: Lugo, Daniel
name: del Pilar Pastor Durango, Maria
name: Castaño, Laura
name: Salazar, Pamela
name: Maquilón, Julieth
name: Giraldo, Claudia
name: Contreras, Jesús
name: Ramírez, Paola
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences

description: Reporte del Dialogo Deliberativo: Verificación y validación externa de la Ruta Integral de Atención en Salud RIAS para amputaciones de miembro inferior por causas traumáticas y neurovasculares.
Appendopyricularia guttulata Y. Wang, H. W. Shen & Z. L. Luo, sp. nov.
Creators: name: Wang, Ying
name: Bao, Dan-Feng
name: Shen, Hong-Wei
name: Yang, Lin
name: Luo, Zong-Long
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Sordariomycetes
Barbatosphaeriaceae
Appendopyricularia
Appendopyricularia guttulata

description: Appendopyricularia guttulata Y. Wang, H.W. Shen & Z.L. Luo, sp. nov. FIGURE. 2
Fungal Names number: FN 571910
 Etymology:— Referring to the conidia with large guttules.
 Holotype:— KUN-HKAS 130433
 Saprobic on submerged decaying wood in freshwater habitats. Sexual morph: Undetermined. Asexual morph: Colonies on substratum superficial, effuse, dark brown. Mycelium partly immersed, branched, smooth, brown, septate hyphae. Conidiophores 92–117 × 4–6 μm (x = 104.5 × 5 μm, n = 20), macronematous, mononematous, erect, straight or slightly flexuous, smooth, brown to hyaline thick-walled, 3–5-septate. Conidiogenous cells 43–53 × 4–5 μm (x = 47.7 × 4.8 μm, n = 18) integrated or branched, terminal, polyblastic, hyaline, subdenticulate. Conidia 30–33 × 4–5 μm (x = 31.5 × 4.9 μm, n = 30), acrogenous, solitary, hyaline, smooth, guttulate, fusoid, 3–4-septate, hilum truncate, with flexuous central apical appendage, 22–29 µm long.
 Culture characteristics: Conidia germinating on PDA within 12 hours and germ tubes produced from the basal, apical and periphery cell of conidia. Colonies growing on PDA, reaching 10 mm diameter in 10 days at 22 ◦ C, with sparse to moderate aerial mycelium and feathery margins, circular, edge entire, surface white, reverse honey to white. Material examined: China, Yunnan Province, Dianchi Lake (Altitude: 1,860m, 24°49′14.1567″N, 102°45′57.5845″E), on submerged decaying wood, 18 February 2023, Hong-Wei Shen, L-1636 (KUN-HKAS 130433, holotype), ex-type culture, CGMCC 3.25401= KUNCC 23-13169.
 Notes: Appendopyricularia juncicola was introduced by Crous et al. (2022) based on morphological and phylogenetic evidence. In the multigene phylogenetic analysis of this study, Appendopyricularia guttulata clustered to A. juncicola with 100% ML and 1.00 PP statistical support. Morphologically, A. guttulata has longer conidiophores than A. juncicola (92–117 × 4–6 μm vs. 7–30 × 3–4μm), and the central apical appendage of A. guttulata is longer than A. juncicola (22–29 vs. 4–15 µm). The conidia of A. guttulata (30–33 × 4–5 μm) are larger than A. juncicola (15–20 × 3–4 µm), and with 3–5 larger guttulate cells. In addition, comparison of ITS sequences between A. guttulata and A. juncicola showed 3.68% (18/489 bp) nucleotide differences with 7 gaps. Based on morphological and phylogenetic analysis, we introduce A. guttulata as a new species.
description: Published as part of Wang, Ying, Bao, Dan-Feng, Shen, Hong-Wei, Yang, Lin & Luo, Zong-Long, 2024, Appendopyricularia guttulata sp. nov., a lignicolous freshwater fungus from Dianchi Lake in Yunnan, China, pp. 55-64 in Phytotaxa 660 (1) on pages 58-59, DOI: 10.11646/phytotaxa.660.1.5, http://zenodo.org/record/13218020
МАКТАБГАЧА ЁШДАГИ БОЛА ИНҚИРОЗИНИНГ ПСИХОЛОГИК ХУСУСИЯТЛАРИ
Creators: name: Шахноза Жураева
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: ота-она
фарзанд
мактабгача ѐш
инқироз
психологик.
родитель
ребенок
дошкольник
кризис
психологический.

description: Мақолада мактабгача ѐшдаги болаларнинг психологик хусусиятлари ѐритилган. Уч ѐшдаги болаларда юз берадиган инқирозли вазиятларни психологик тахлили берилган. Мактабгача ѐшдаги болаларни инқирозли вазиятларини хориж олимлари томонидан ўрганилганлиги тахлил қилинган. Инқирозли вазиятларда болалар билан қандай муносабат бўлиш учун психологик тавсиялар берилган.
description: В статье описаны психологические особенности детей дошкольного возраста. Дан психологический анализ кризисных ситуаций, возникающих у детей трех лет. Проанализировано, что кризисные ситуации дошкольников изучались зарубежными учеными. Даются психологические советы о том, как вести себя с детьми в кризисных ситуациях.
השפעת מודל דילול המשאבים ומידת הדתיות על שליטה עצמית
Creators: name: Friedman, Yael
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: זוהי ההרשמה מראש למחקר שלנו במסגרת קורס 'פסיכולוגיה ניסויית'.
Tissue and subcellular distribution of CLIC1
Creators: name: Edwards, John C
name: Bruno, Jonathan
Publisher: name: BioMed Central Ltd
Year: 2007

description: Abstract Background CLIC1 is a chloride channel whose cellular role remains uncertain. The distribution of CLIC1 in normal tissues is largely unknown and conflicting data have been reported regarding the cellular membrane fraction in which CLIC1 resides. Results New antisera to CLIC1 were generated and were found to be sensitive and specific for detecting this protein. These antisera were used to investigate the distribution of CLIC1 in mouse tissue sections and three cultured cell lines. We find CLIC1 is expressed in the apical domains of several simple columnar epithelia including glandular stomach, small intestine, colon, bile ducts, pancreatic ducts, airway, and the tail of the epididymis, in addition to the previously reported renal proximal tubule. CLIC1 is expressed in a non-polarized distribution in the basal epithelial cell layer of the stratified squamous epithelium of the upper gastrointesitinal tract and the basal cells of the epididymis, and is present diffusely in skeletal muscle. Distribution of CLIC1 was examined in Panc1 cells, a relatively undifferentiated, non-polarized human cell line derived from pancreatic cancer, and T84 cells, a human colon cancer cell line which can form a polarized epithelium that is capable of regulated chloride transport. Digitonin extraction was used to distinguish membrane-inserted CLIC1 from the soluble cytoplasmic form of the protein. We find that digitonin-resistant CLIC1 is primarily present in the plasma membrane of Panc1 cells. In T84 cells, we find digitonin-resistant CLIC1 is present in an intracellular compartment which is concentrated immediately below the apical plasma membrane and the extent of apical polarization is enhanced with forskolin, which activates transepithelial chloride transport and apical membrane traffic in these cells. The sub-apical CLIC1 compartment was further characterized in a well-differentiated mouse renal proximal tubule cell line. The distribution of CLIC1 was found to overlap that of megalin and the sodium-phosphate cotransporter, NaPi-II, which are markers of the apical endocytic/recycling compartment in proximal tubule. Conclusion The cell and tissue specific patterns of CLIC1 expression suggest it may play distinct roles in different cell types. In certain polarized columnar epithelia, it may play a role in apical membrane recycling.
title: Constraints on Phonological Statistical Learning in Adults
Creators: name: Bond, Samuel
Publisher: name: Oxford Brookes University
Year: 2023

description: Auditory statistical learning studies typically explore whether participants can compute a given statistical pattern from an artificial language (e.g., classic transitional probability studies). Even when studies include several statistical cues, these cues often coincide (e.g., exploring how prosody impacts transitional probability learning). However, outside of controlled experiments, statistical learners face an overwhelming number of cues and need to determine what statistics to compute over others. The aim of this thesis was to identify the statistical information adults computed from artificial languages with concurrent, competing cues. Participants heard artificial languages containing sequences of CVC words. The voicing (voiced, voiceless), manner of articulation (plosive, nasal, fricative) and non-adjacent pairings of consonants were controlled so each language contained three concurrent types of statistical information: the single-feature bias (most codas were voiced), the multiple-feature bias (most codas for one manner of articulation - e.g., fricatives - were voiceless), and the within-word consonant relationships (onsets and codas co-occurred). Statistical learning was measured using a 2AFC task. Sixteen experiments contributed to this thesis (guide in Appendix 10). Convergent evidence suggested adults computed the single-feature bias (Experiment 1, Experiment 2, Experiment 3, Experiment 4, Experiment 9, Experiment 10, Experiment 11, Experiment 12). Participants computed this bias when carried by plosive and nasals (Experiment 1, Experiment 2, Experiment 9, Experiment 10, Experiment 11, Experiment 12) and fricative and nasals (Experiment 3, Experiment 4). Remarkably, adults computed this bias after 14 seconds of exposure (Experiment 12); generalising to new words after 7 minutes (Experiment 10). Adults also computed the multiple-feature bias (Experiment 5, Experiment 6, Experiment 7), but only when it was strong (≥90%), and only generalised this bias when it was presented with a weak concurrent single-feature bias (Experiment 7). There was a lack of evidence to suggest adults computed the within-word consonant relationships. A novel word search task provided supplementary evidence (Experiments 13a and 13b, Experiments 2, 5-7, Experiments 9-12). Adults readily compute statistics over one phonological feature (voicing) and can generalise to new words. Computations over two phonological features (voicing and manner of articulation) are possible given the right context. There are constraints on our auditory statistical learning mechanism to compute certain cues when faced with concurrent statistics. However, flexibility in our mechanism means we can circumvent these constraints. The nature of these constraints, the factors driving statistical learning and the theoretical implications are discussed.
MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs
Creators: name: Hammond, Scott
Publisher: name: BioMed Central Ltd
Year: 2010

description: Abstract Background Recent studies have shown that microRNAs (miRNAs) play roles in tumorigenesis and are reliable classifiers of certain cancer types and subtypes. However, the role of miRNAs in the pathogenesis and diagnosis of small cell carcinoma (SCLC), the majority of which represent the most aggressive lung tumors, has not been investigated. Methods In order to explore miRNA involvement in the pathogenesis of small cell lung carcinoma (SCLC) and the potential role of miRNAs in SCLC diagnosis, we compared the miRNA expression profile of a set of SCLC cell lines to that of a set of non-small cell lung cancer (NSCLC) cell lines and normal immortalized human bronchial epithelial cells (HBECs) using microarray analysis. Results Our results show that miRNA profiles reliably distinguish SCLC cell lines from NSCLC and HBEC cell lines. Further analysis of the miRNA expression profile of the two subtypes of lung cancer cell lines indicates that the expression levels of the majority of the miRNAs that are differentially expressed in SCLC cells relative to NSCLC cells and HBECs show a progressive trend from HBECs to NSCLC cells to SCLC cells. Conclusions The distinctive miRNA expression signature of SCLCs relative to NSCLCs and HBECs suggests that miRNA profiles have the potential to serve as a diagnostic marker of SCLC lung tumors. The progressive trend of miRNA profile changes from HBECs to NSCLCs to SCLCs suggests a possible pathological relationship between SCLCs and NSCLCs, and suggests that the increasing dysregulation of miRNA expression may play a role in lung tumor progression. The specific role of these miRNAs in lung tumor pathogenesis and differentiation need to be investigated further in future studies.
Study 1
Creators: name: Dobson, Kiersten
name: Stanton, Sarah
name: Campbell, Lorne
name: Pink, Jennifer
name: Lab, SHaRe
name: Lab, Relationships and Well-Being
Publisher: name: Open Science Framework
Year: 2022

description: We have existing studies (some previously not registered, including this study) which demonstrate that more (vs. less) avoidantly attached individuals tend to initiate sexual activity less and reject their partners’ sexual advances more. We now seek to test models examining the relationship between attachment avoidance, sexual rejection, and sexual satisfaction (see Data Analytic Plan).
Transport coefficients of graphene: Interplay of impurity scattering, Coulomb interaction, and optical phonons
Creators: name: Xie, Hong-Yi
name: Foster, Matthew S.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the electric and thermal transport of the Dirac carriers in monolayer graphene using the Boltzmann-equation approach. Motivated by recent thermopower measurements [F. Ghahari, H.-Y.~Xie, T. Taniguchi, K. Watanabe, M.~S.~Foster, and P.~Kim, Phys.\ Rev.\ Lett.\ {\bf 116}, 136802 (2016)], we consider the effects of quenched disorder, Coulomb interactions, and electron--optical-phonon scattering. Via an unbiased numerical solution to the Boltzmann equation we calculate the electrical conductivity, thermopower, and electronic component of the thermal conductivity, and discuss the validity of Mott's formula and of the Wiedemann-Franz law. An analytical solution for the disorder-only case shows that screened Coulomb impurity scattering, although elastic, violates the Wiedemann-Franz law even at low temperature. For the combination of carrier-carrier Coulomb and short-ranged impurity scattering, we observe the crossover from the interaction-limited (hydrodynamic) regime to the disorder-limited (Fermi-liquid) regime. In the former, the thermopower and the thermal conductivity follow the results anticipated by the relativistic hydrodynamic theory. On the other hand, we find that optical phonons become nonnegligible at relatively low temperatures and that the induced electron thermopower violates Mott's formula. Combining all of these scattering mechanisms, we obtain the thermopower that quantitatively coincides with the experimental data.
description: 20 pages, 9 figures