cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 8 of SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution
Creators: name: Stow, Emily C.
name: Baddoo, Melody
name: LaRosa, Alexis J.
name: LaCoste, Dawn
name: Deininger, Prescott
name: Belancio, Victoria
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8 Expression patterns of genes involved in spermatogenesis in human testes. Cell types are abbreviated as follows: Spermatogonial Stem Cells (SSCs), Differentiating Spermatogonia (Diff Spg), Spermatocytes (Spcyt), Round Spermatids (RS), Elongating Spermatids (ES), Condensing Spermatids (CS), Macrophages (Macro), Endothelial (Endo), Myoid (Myo), and Sertoli (Ser). A. 24 yo Human Testis gene expression patterns for PRM1 (A1), SPAG6 (A2), TNP1 (A3), and TNP2 (A4). B. 25 yo Human Testis gene expression patterns for PRM1 (B1), SPAG6 (B2), TNP1 (B3), and TNP2 (B4). C. The heat map shows the normalized expression patterns for each cell type and gene in 24 yo Testis (top) and 25 yo Testis (bottom). The asterisks indicate a significant change in gene expression in the cell type compared to the preceding cell type in the row (P < 0.0001). D. The normalized expression levels for 24 yo testis cell types from Seurat analysis are shown (Wilcoxon rank sum, P < 0.0001).
Using Categorization of Problems as an Instructional Tool to Help Introductory Students Learn Physics
Creators: name: Mason, Andrew
name: Singh, Chandralekha
Publisher: name: arXiv
Year: 2016
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: The ability to categorize problems based upon underlying principles, rather than contexts, is considered a hallmark of expertise in physics problem solving. With inspiration from a classic study by Chi, Feltovich, and Glaser, we compared the categorization of 25 introductory mechanics problems based upon similarity of solution by students in large calculus-based introductory courses with physics faculty and Ph.D. students. Here, we summarize the study and suggest that a categorization task, especially when conducted with students working with peers in small groups, can be an effective pedagogical tool to help students in introductory physics courses learn to discern the underlying similarity between problems with diverse contexts but the same underlying physics principles.
description: 6 pages, 1 figure. arXiv admin note: substantial text overlap with arXiv:1602.07677
Polyprenylated xanthones with potential anti-inflammatory and anti-HIV effects from the stems and leaves of Cratoxylum cochinchinense (Lour.) Blume
Creators: name: Zhang, Yong
name: Rao, You-Di
name: Yu, Jing-Su
name: Hu, Jia-Yi
name: Hu, Wen-Hui
name: Li, Shu-Ri
name: Yang, Hui
name: Liu, Yan-Ping
name: Fu, Yan-Hui
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: A phytochemical study on the stems and leaves of Cratoxylum cochinchinense (Lour.) Blume resulted in the isolation and characterisation of a new polyprenylated xanthone, cratocochinone (1), as well as seven known analogues, fuscaxanthone K (2), pruniflorone Q (3), 1,3,5,8-tetrahy-droxy- 2-(3-methybut-2-enyl)-4-(3,7-dimethylocta-2,6-dienyl) xanthone (4), cochinensoxanthone (5), cratoxylum-xanthone B (6), cochinchinone I (7) and cochinchinone K (8). The chemical structure of 1 was determined by comprehensive spectral analyses. The known compounds 2 − 8 were identified by comparing their experimental spectroscopic data with those reported data in the literature. The anti-inflammatory and anti-HIV effects of all isolates 1–8 were evaluated. As a result, compounds 1–8 showed remarkable inhibitory effects against nitric oxide (NO) production induced by lipopolysaccharide in mouse macrophage RAW 264.7 cells showing IC50 values ranging from 0.68 ± 0.06 to 10.27 ± 0.18 μM. Meanwhile, compounds 1–8 displayed notable anti-HIV-1 reverse transcriptase (RT) effects with EC50 values ranging from 0.19 to 10.72 µM.
What is the Computational Value of Finite Range Tunneling?
Creators: name: Denchev, Vasil S.
name: Boixo, Sergio
name: Isakov, Sergei V.
name: Ding, Nan
name: Babbush, Ryan
name: Smelyanskiy, Vadim
name: Martinis, John
name: Neven, Hartmut
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum annealing (QA) has been proposed as a quantum enhanced optimization heuristic exploiting tunneling. Here, we demonstrate how finite range tunneling can provide considerable computational advantage. For a crafted problem designed to have tall and narrow energy barriers separating local minima, the D-Wave 2X quantum annealer achieves significant runtime advantages relative to Simulated Annealing (SA). For instances with 945 variables, this results in a time-to-99%-success-probability that is $\sim 10^8$ times faster than SA running on a single processor core. We also compared physical QA with Quantum Monte Carlo (QMC), an algorithm that emulates quantum tunneling on classical processors. We observe a substantial constant overhead against physical QA: D-Wave 2X again runs up to $\sim 10^8$ times faster than an optimized implementation of QMC on a single core. We note that there exist heuristic classical algorithms that can solve most instances of Chimera structured problems in a timescale comparable to the D-Wave 2X. However, we believe that such solvers will become ineffective for the next generation of annealers currently being designed. To investigate whether finite range tunneling will also confer an advantage for problems of practical interest, we conduct numerical studies on binary optimization problems that cannot yet be represented on quantum hardware. For random instances of the number partitioning problem, we find numerically that QMC, as well as other algorithms designed to simulate QA, scale better than SA. We discuss the implications of these findings for the design of next generation quantum annealers.
description: 17 pages, 13 figures. Edited for clarity, in part in response to comments. Added link to benchmark instances
Pre-imaginal exposure to mancozeb induces morphological and behavioral deficits and oxidative damage in Drosophila melanogaster
Creators: name: Ziech, Cynthia Camila
name: Rodrigues, Nathane Rosa
name: Macedo, Giulianna Echeverria
name: Gomes, Karen Kich
name: Martins, Illana Kemmerich
name: Franco, Jeferson Luis
name: Posser, Thaís
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology

description: Mancozeb (MZ), a manganese/zinc containing ethylene-bis-dithiocarbamate, is a broad-spectrum fungicide. Chronic exposure to MZ has been related to several organisms’ neurological, hormonal, and developmental disorders. However, little is known about the post-natal effects of developmental exposure to MZ. In this study, Drosophila melanogaster was subjected to a pre-imaginal (eggs-larvae-pupae stage) model of exposure to MZ at 0.1 and 0.5 mg/mL. The emergence rate, body size, locomotor performance, sleep patterns, and molecular and biochemical parameters were evaluated in post-emerged flies. Results demonstrate that pre-imaginal exposure to MZ significantly impacted early emerged flies. Additionally, reduced progeny viability, smaller body size and delaying in emergence period, locomotor impairment, and prolonged sleep time were observed. Content of glucose, proteins, and triglycerides were altered, and the bioenergetics efficiency and oxidative phosphorylation at complex I were inhibited. mRNA stade state levels of genes responsive to stress, metabolism, and regulation of circadian cycle (Nrf2, p38, Hsp83, Akt1, GPDH, tor, per, tim, dILP2, and dILP6) were augmented, pointing out to stimulation of antioxidant defenses, insulin-dependent signaling pathway activation, and disruption of sleep regulation. These data were followed by increased lipid peroxidation and lower glutathione levels. In addition, the activity of catalase and glutathione-S-transferase were induced, whereas superoxide dismutase was inhibited. Together, these results demonstrate that developmental exposure to MZ formulation led to phenotype and behavioral alterations in young flies, possibly related to disruption of energetic metabolism, oxidative stress, and deregulation of genes implied in growth, sleep, and metabolism.
Unser Glaube: Die Bekenntnisschriften der evangelisch-lutherischen Kirche, Ausgabe für die Gemeinde
Creators: name: Eber, Jochen
Publisher: name: Jahrbuch für evangelikale Theologie
Year: 2025

description: 1823806007
description: Jahrbuch für evangelikale Theologie, V. 28 (2014): Jahrbuch für evangelikale Theologie, Band 28
Phase structures of 4D stringy charged black holes in canonical ensemble
Creators: name: Jia, Qiang
name: Lu, J. X.
name: Tan, Xiao-Jun
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the thermodynamics and phase structures of the asymptotically flat dilatonic black holes in 4 dimensions, placed in a cavity {\it a la} York, in string theory for an arbitrary dilaton coupling. We consider these charged black systems in canonical ensemble for which the temperature at the wall of and the charge inside the cavity are fixed. We find that the dilaton coupling plays the key role in the underlying phase structures. The connection of these black holes to higher dimensional brane systems via diagonal (double) and/or direct dimensional reductions indicates that the phase structures of the former may exhaust all possible ones of the latter, which are more difficult to study, under conditions of similar settings. Our study also shows that a diagonal (double) dimensional reduction preserves the underlying phase structure while a direct dimensional reduction has the potential to change it.
description: 32 pages, 4 figures, 2 tables, a footnote on bubble phase added
Dinaphthodiospyrol H: a natural α-glucosidase inhibibitor extracted from Diospyros kaki L.f
Creators: name: Rauf, Abdur
name: AlOmar, Taghrid S.
name: Rashid, Umer
name: Ahmad, Zubair
name: Kanwal, Sofia
name: Almasoud, Najla
name: Muhammad, Naveed
name: Anyanwu, Margrate
name: Gianoncelli, Alessandra
name: Ribaudo, Giovanni
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The roots of Diospyro kaki L.f., known for their anti-inflammatory, antimicrobial and antidiabetic properties, are the source of dimeric naphthoquinones, including dinaphthodiospyrol H. α-Glucosidase is an enzyme involved in regulation of blood glucose levels and its inhibition helps in the control of the postprandial hyperglycaemia. In this study, an in vitro evaluation of dinaphthodiospyrol H was carried out and the compound inhibited α-glucosidase with an IC50 value of 57.38 ± 0.87 µg/mL, revealing a significant potential that supports the traditional application of D. kaki in the treatment of diabetes mellitus. Additionally, computational studies, including docking and molecular dynamics, were used to investigate ligand-target complex and showed that the compound targets the same site with which acarbose interacts. Overall, the findings provide new basis to translate the traditional use of D. kaki into modern medicinal chemistry.
title: Konzeptionierung und Implementierungsplanung eines interprofessionellen hausarztbasierten Gesundheitszentrums auf der schwäbischen Alb
Creators: name: Sturm, H.
name: Roller, G.
name: Joos, S.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Implentationsprozess
subject: interprofessionelle Zusammenarbeit;
subject: Patientenzentrierte Versorgung;
subject: 610 Medical sciences; Medicine

description: Hintergrund: Der demographische Wandel erfordert eine koordinierte und interdisziplinäre Patientenversorgung, Nachwuchsärzte fordern andere Rahmenbedingungen für ihr Arbeitsumfeld. Insbesondere in strukturschwachen Gebieten braucht es deshalb neue Versorgungsformen. Auf der ländlichen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 50. Kongress für Allgemeinmedizin und Familienmedizin
title: Übernimmt der Notarzt Aufgaben der hausärztlichen Versorgung? Eine Analyse aller Notarzteinsätze einer sächsischen Kleinstadt
Creators: name: Meixner, M.
name: Voigt, K.
name: Bergmann, A.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Außerklinische Notfallversorgung
subject: Hausbesuche
subject: Notarztdienst
subject: 610 Medical sciences; Medicine

description: Hintergrund: Angaben der Kassenärztlichen Vereinigung Sachsen zufolge ergibt sich eine deutliche Reduktion der Einsatzzahlen im kassenärztlichen Notdienst bei gleichzeitigem Anstieg der Einsatzzahlen der Notarzteinsätze in den letzten Jahren. Die Bundesvereinigung der Arbeitsgemeinschaften[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 50. Kongress für Allgemeinmedizin und Familienmedizin
Finite temperature elastic constants of paramagnetic materials within the disordered local moment picture from ab initio molecular dynamics calculations
Creators: name: Mozafari, Elham
name: Shulumba, Nina
name: Steneteg, Peter
name: Alling, Björn
name: Abrikosov, Igor A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present a theoretical scheme to calculate the elastic constants of magnetic materials in the high-temperature paramagnetic state. Our approach is based on a combination of disordered local moments picture and ab initio molecular dynamics (DLM-MD). Moreover, we investigate a possibility to enhance the efficiency of the simulations of elastic properties using recently introduced method: symmetry imposed force constant temperature dependent effective potential (SIFC-TDEP). We have chosen cubic paramagnetic CrN as a model system. This is done due to its technological importance and its demonstrated strong coupling between magnetic and lattice degrees of freedom. We have studied the temperature dependent single-crystal and polycrystalline elastic constants of paramagentic CrN up to 1200 K. The obtained results at T= 300 K agree well with the experimental values of polycrystalline elastic constants as well as Poisson ratio at room temperature. We observe that the Young's modulus is strongly dependent on temperature, decreasing by ~14% from T=300 K to 1200 K. In addition we have studied the elastic anisotropy of CrN as a function of temperature and we observe that CrN becomes substantially more isotropic as the temperature increases. We demonstrate that the use of Birch law may lead to substantial errors for calculations of temperature induced changes of elastic moduli. The proposed methodology can be used for accurate predictions of mechanical properties of magnetic materials at temperatures above their magnetic order-disorder phase transition.
description: 1 table, 3 figures
Additional file 9 of SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution
Creators: name: Stow, Emily C.
name: Baddoo, Melody
name: LaRosa, Alexis J.
name: LaCoste, Dawn
name: Deininger, Prescott
name: Belancio, Victoria
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9. Analysis of L1 mRNA expression in human testes with bulk RNA-Seq and scRNA-Seq. A. The L1 FPKM values for L1 loci listed on the X-axis are shown for two 20 yo human testis bulk RNA-Seq samples. The number of expressed L1 loci shared between the two replicates is shown in the Venn diagram with the percentage of shared expressed loci indicated above the diagram. B. The L1 RPM values for L1 loci listed on the X-axis are shown for a 24 yo and a 25 yo human testis scRNA-Seq sample. The number of expressed L1 loci shared between the two replicates is shown in the Venn diagram with the percentage of shared expressed loci indicated above the diagram. C. The million mapped reads per cell for all cell types in the 24 yo scRNA-Seq dataset is shown in the scatter plot. Statistics are shown for sperm cells and sperm progenitor cell types only. D. The L1 mRNA expression level per cell for all 24 yo testis cell types is shown in the scatter plot. E. The number of expressed L1 loci per cell for all 24 yo testis cell types is shown in the scatter plot. F. The million mapped reads per cell for all cell types in the 24 yo scRNA-Seq dataset is shown in the scatter plot. Statistics are shown for sperm cells and sperm progenitor cell types only. G. The L1 mRNA expression level per cell for all 25 yo testis cell types is shown in the scatter plot. H. The number of expressed L1 loci per cell for all 25 yo testis cell types is shown in the scatter plot. I. The L1 RPM values for L1 loci indicated on the X-axis are shown for each sperm cell type in the 25 yo human testis sample. The Venn Diagram shows the number of expressed L1 loci shared by the sperm cell types with the percentage of shared expressed L1 loci indicated above the diagram. J. The L1 FPKM values for bulk RNA-Seq (left y-axis) and L1 RPM values for scRNA-Seq (right y-axis) of human testis are shown in the dot-plot. Orange circles indicate L1 loci with detected expression in the bulk dataset that were not detected to be expressed in scRNA-Seq. The nested Venn diagram shows the number of shared expressed L1 loci from the bulk and scRNA-Seq datasets. K. The violin plot shows the FPKM values for expressed L1 loci unique to the bulk dataset and those shared between bulk and scRNA-Seq (t-test, **,< 0.0021).
title: Medikamentöse Raucherentwöhnung in der Hausarztpraxis
Creators: name: Nohutcu, G.
name: Schnakenberg, R.
name: Weckbecker, K.
name: Bleckwenn, M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Bupropion Vareniclin
subject: Nikotinersatztherapie
subject: Raucherentwöhnung
subject: 610 Medical sciences; Medicine

description: Hintergrund: Rauchen ist ein wesentlicher Risikofaktor für kardiovaskuläre und pulmonale Erkrankungen. Die Chance auf eine anhaltende Rauchfreiheit wird durch eine professionelle Raucherentwöhnung und den Einsatz einer Nikotinersatztherapie (NET), Vareniclin oder Bupropion um das 2-3-Fache[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 50. Kongress für Allgemeinmedizin und Familienmedizin
title: Manuelle Therapie und Funktionskapazität bei akuten unspezifischen Rückenschmerzen
Creators: name: Krüger, K.
name: Blase, L.
name: Schmiemann, G.
name: Lingner, H.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Intervention
subject: Manuelle Therapie
subject: Rückenschmerzen
subject: 610 Medical sciences; Medicine

description: Hintergrund: Mit einer Lebenszeitprävalenz von 74-85% in der deutschen Bevölkerung sind Rückenschmerzen ein häufiger Behandlungsanlass in der hausärztlichen Versorgung. Akute Rückenschmerzen haben wesentlichen Anteil an den Krankmeldungen und führen bei Betroffenen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 50. Kongress für Allgemeinmedizin und Familienmedizin
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP
Creators: name: Dogra, Ashish
name: Kour, Dilpreet
name: Gour, Abhishek
name: Bhardwaj, Mahir
name: Bag, Swarnendu
name: Dhiman, Shakti Kumar
name: Kumar, Ajay
name: Singh, Gurdarshan
name: Nandi, Utpal
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Cancer

description: Diclofenac is a widely prescribed anti-inflammatory drug having cardiovascular complications as one of the main liabilities that restrict its therapeutic use. We aimed to investigate for any role of rutin against diclofenac-induced cardiac injury with underlying mechanisms as there is no such precedent to date. The effect of rutin (10 and 20 mg/kg) was evaluated upon concomitant oral administration for fifteen days with diclofenac (10 mg/kg). Rutin significantly attenuated diclofenac-induced alterations in the serum cardiac markers (LDH, CK-MB, and SGOT), serum cytokine levels (TNF-α and IL-6), and oxidative stress markers (MDA and GSH) in the cardiac tissue. Histopathological examination and Scanning Electron Microscopy (SEM) findings displayed a marked effect of rutin to prevent diclofenac-mediated cardiac injury. Altered protein expression of myocardial injury markers (cTnT, FABP3, and ANP) and apoptotic markers (Bcl-2 and Caspase-3) in the cardiac tissue upon diclofenac treatment was considerably shielded by rutin treatment. MYL3 was unaffected due to diclofenac or rutin treatment. Rutin also significantly improved diclofenac-induced gastrointestinal and hepatic alterations based on the observed ameliorative effects in key mediators, oxidative stress markers, histopathology examination, and SEM findings. Overall results suggest that rutin can protect the diclofenac-induced cardiac injury by lowering oxidative stress, inhibiting inflammation, and reducing apoptosis. Further research work directs toward the development of phytotherapeutics for cardioprotection.
title: Biomechanische Analyse von Funktion und Dehnung des anterolateralen Ligamentes
Creators: name: Drews, Björn
name: Kessler, Oliver
name: Franz, Wolfgang
name: Freutel, Maren
name: Dürselen, Lutz
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: ALL
subject: Biomechanik
subject: Rotationsstabilität
subject: 610 Medical sciences; Medicine

description: Fragestellung: Nachdem die Double-bundle Technik in der Rekonstruktion des vorderen Kreuzbandes (VKB) das Problem der verbleibenden Rotationsinstabilität in manchen Fällen nicht lösen konnte, wurde nach neuen Antworten für dieses Problem gesucht. Die extraartikuläre Stabilisierung[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
Two dipolar atoms in a harmonic trap
Creators: name: Ołdziejewski, Rafał
name: Górecki, Wojciech
name: Rzążewski, Kazimierz
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Two identical dipolar atoms moving in a harmonic trap without an external magnetic field are investigated. Using the algebra of angular momentum a semi - analytical solutions are found. We show that the internal spin - spin interactions between the atoms couple to the orbital angular momentum causing an analogue of Einstein - de Haas effect. We show a possibility of adiabatically pumping our system from the s-wave to the d-wave relative motion. The effective spin-orbit coupling occurs at anti-crossings of the energy levels.
description: 8 pages, 2 figures, submitted to Physical Review A
title: Macro DE - Executive Summary - DE2002 / WP3.3: Technology Development Opportunities
Creators: name: ETI
Publisher: name: ETI
Year: 2013
Subjects: subject: Distributed Energy
subject: ENERGY EFFICIENCY (Residential and commercial)

description: The objective of the Distributed Energy (DE) Programme is to increase the uptake of DE through the development of integrated systems in order to reduce through-life costs, improve ease of installation and increase efficiency in the combined generation of heat and electricity. Within this programme framework the objective of the Macro DE FRP will develop and validate a software methodology to enable the design of optimised DE solutions where clusters of demand sites are linked with appropriate DE supply equipment.The project will quantify the opportunity for Macro level DE (up to 50MW) in the UK and the potential to accelerate the development of appropriate technology by 2020 for the purposes of significant implementation by 2030.

The objective of this task was to characterise the required 100kWe – 50MWe distributed energy equipment to form a library of DE supply equipment models and to project, by consultation, the technical improvement of these technologies in 2020 and 2030. This has been accomplished and the technology characteristics documented in an extensive spreadsheet.

The projected technical improvements (2020 – 2030) were obtained from consultations with manufacturers and experts in the industry. For the mature technology like gas engine, the projected technical advancement is the future technical standard which is set by the main players in the field. For less developed technologies like fuel cells, the projected technical advancement is the technical judgment from the manufacturers who were contacted.
title: 3-13 Jahresergebnisse SALTO Sprunggelenksendoprothese
Creators: name: Stöbich, Michael
name: Böhler, Nikolaus
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Sprunggelenksendoprothese
subject: Sprunggelenk
subject: 610 Medical sciences; Medicine

description: Fragestellung: Seit 2002 wird die SALTO 3-Komponentenprothese der Firma Tornier in ihrer mobile-bearing-Variante an unserer Klinik zur Versorgung der oberen Sprunggelenksarthrose verwendet. Das Ziel dieser Nachuntersuchung ist die Erhebung der kurz- bis mittelfristigen Ergebnisse, sowohl klinisch als[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
Systematic estimation of theoretical uncertainties in the calculation of the pion-photon transition form factor using light-cone sum rules
Creators: name: Mikhailov, S. V.
name: Pimikov, A. V.
name: Stefanis, N. G.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider the calculation of the pion-photon transition form factor $F^{γ^*γπ^0}(Q^2)$ within light-cone sum rules focusing attention to the low-mid region of momenta. The central aim is to estimate the theoretical uncertainties which originate from a wide variety of sources related to (i) the relevance of next-to-next-to-leading order radiative corrections (ii) the influence of the twist-four and the twist-six term (iii) the sensitivity of the results on auxiliary parameters, like the Borel scale $M^2$, (iv) the role of the phenomenological description of resonances, and (v) the significance of a small but finite virtuality of the quasireal photon. Predictions for $F^{γ^*γπ^0}(Q^2)$ are presented which include all these uncertainties and found to comply within the margin of experimental error with the existing data in the $Q^2$ range between 1 and 5 GeV$^2$, thus justifying the reliability of the applied calculational scheme. This provides a solid basis for confronting theoretical predictions with forthcoming data bearing small statistical errors.
description: 15 pages, 4 figures. Version 3 includes complete Fig. 4 and all Eqs.(B7). Conclusions unchanged; matches version to appear in Phys. Rev. D
Subleading soft photons and large gauge transformations
Creators: name: Campiglia, Miguel
name: Laddha, Alok
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Lysov, Pasterski and Strominger have shown how Low's subleading soft photon theorem can be understood as Ward identities of new symmetries of massless QED. In this paper we offer a different perspective and show that there exists a class of large $U(1)$ gauge transformations such that (i) the associated (electric and magnetic) charges can be computed from first principles (ii) their Ward identities are equivalent to Low's theorem. Our framework paves the way to analyze the sub-subleading theorem in gravity in terms of Ward identities associated to large diffeomorphisms.
description: 17 pages
title: Operationsbezogene Ausbildungskosten in Orthopädie und Unfallchirurgie
Creators: name: Pförringer, Dominik
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Facharztausbildung
subject: OP-Dauer
subject: Schnitt-Naht-Zeit
subject: Ausbildungskosten
subject: Weiterbildung
subject: 610 Medical sciences; Medicine

description: Fragestellung: Hintergrund: Unfallchirurgie ist ein Lehrfach, in dem die Ausbildung zum Facharzt das Durchlaufen einer technischen und zeitlichen Lernkurve durch das repetitive Erarbeiten von handwerklichen Fähigkeiten bedarf. Dies resultiert in verlängerten OP-Zeiten und -Kosten. Ziel[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
Mühling, Andreas / Opitz, Peter (Hg.), Reformierte Bekenntnisschriften, Band 3/1: 1570-1599
Creators: name: Eber, Jochen
Publisher: name: Jahrbuch für evangelikale Theologie
Year: 2025

description: 1823805876
description: Jahrbuch für evangelikale Theologie, V. 28 (2014): Jahrbuch für evangelikale Theologie, Band 28
title: Vascularization of Large Bone Implants Using Bioreactor Technology – A Pilot Study
Creators: name: Vater, Corina
name: Aper, Thomas
name: Milan, Falk
name: Liebers, Cornelia
name: Wilhelmi, Mathias
name: Stiehler, Maik
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: tissue engineering
subject: vascularization
subject: critical size defect
subject: 610 Medical sciences; Medicine

description: Objectives: Large bone defects denote a major socioeconomic issue. In this context, the concept of bone tissue engineering represents an innovative, promising cell-based strategy for effective bone regeneration. Within this project a fully tissue-engineered vascularized bone implant consisting of a [for full text, please go to the a.m. URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
GREAT D6.3 Business Models
Creators: name: Ower, Jude
name: Hollins, Paul
name: Kieslinger, Barbara
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Business and management
subject: Business models
subject: Video games
subject: Digital Games
subject: GREAT Project
subject: Climate change
subject: Games technology
subject: Policy dilemmas
subject: Business model canvas
subject: Lean canvas
subject: Value proposition canvas
subject: Serious games interactive
subject: PlanetPlay
subject: Stakeholders
subject: Revenue models
subject: Data curation
subject: Customer segmentation
subject: Sustainability
subject: In-game advertising
subject: Surveys
subject: Policy-makers
subject: Public open data
subject: Ecosystem
subject: Ethics
subject: Continuous improvement
subject: Business-to-business (B2B)
subject: Software-as-a-service (SaaS)
subject: Customer aquisition cost
subject: Lifetime value
subject: Value exchange
subject: Corporate social responsibility
subject: Sustainability strategy

description: This deliverable provides a summary of the research undertaken by the GREAT project in examining the business models applied in the domain of the use of games to link citizens in dialogue with policy makers examining policy dilemmas related to the climate change crisis. The existing and current business models applied by the industrial partners SGI and PlanetPlay are examined, using the combined lenses of three variants of the Business Model Canvas, The Business Model Canvas, The Value Proposition Canvas and the Lean Canvas. This approach exposes the attributes of the partners business models and provides formal conceptualisations of how these organisations function in what is an emerging domain of activity. The assumptions underlying the models, specifically the value propositions, are tested and evaluated in the GREAT case studies currently being undertaken in the accompanying work package 4 of the project. A number of alternative revenue models are considered, and informed by this analysis, and by contemporary business literature, we conducted in-depth interviews with the industrial partners SGI and PlanetPlay, GREAT stakeholder groups and sponsors to further develop refined business models informed by our research. This public report highlights the GREAT partners’ research into the business aspects of the project. It is anticipated that the content will be of interest to a wider audience including the EU, games development studios, policy-makers and potential sponsors of activities.
Time-dependent Aharonov-Bohm effect on the noncommutative space
Creators: name: Ma, Kai
name: Wang, Jian-Hua
name: Yang, Huan-Xiong
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the time-dependent Aharonov-Bohm effect on the noncommutative space. Because there is no net Aharonov-Bohm phase shift in the time-dependent case on the commutative space, therefore, a tiny deviation from zero indicates new physics. Based on the Seiberg-Witten map we obtain the gauge invariant and Lorentz covariant Aharonov-Bohm phase shift in general case on noncommutative space. We find there are two kinds of contribution: momentum-dependent and momentum-independent corrections. For the momentum-dependent correction, there is a cancellation between the magnetic and electric phase shifts, just like the case on the commutative space. However, there is a non-trivial contribution in the momentum-independent correction. This is true for both the time-independent and time-dependent Aharonov-Bohm effects on the noncommutative space. However, for the time-dependent Aharonov-Bohm effect, there is no overwhelming background which exists in the time-independent Aharonov-Bohm effect on both commutative and noncommutative space. Therefore, the time-dependent Aharonov-Bohm can be sensitive to the spatial noncommutativity. \draftnote{The net correction is proportional to the product of the magnetic fluxes through the fundamental area represented by the noncommutative parameter $θ$, and through the surface enclosed by the trajectory of charged particle.} More interestingly, there is an anti-collinear relation between the logarithms of the magnetic field $B$ and the averaged flux $Φ/N$ (N is the number of fringes shifted). This nontrivial relation can also provide a way to test the spatial noncommutativity. For $BΦ/N\sim 1$, our estimation on the experimental sensitivity shows that it can reach the $\rm 10GeV$ scale. This sensitivity can be enhanced by using stronger magnetic field strength, larger magnetic flux, as well as higher experimental precision on the phase shift.
description: 12 pages, 1 figure; v2, accepted version by PLB
title: Evaluationsergebnisse aus der Darmkrebsfrüherkennung: informierte Entscheidung und Inanspruchnahme von Präventionsleistungen
Creators: name: Horenkamp-Sonntag, Dirk
name: Bestmann, Beate
name: Schneider, Udo
name: Engel, Susanne
name: Linder, Roland
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund/Fragestellung: Von 2003 bis 2011 nutzten lediglich 19% der anspruchsberechtigten Männer und 21% der Frauen die Präventionsmöglichkeit bei Darmkrebs. Deshalb wurde in den vergangenen Jahren durch verschiedenste politische Aktivitäten versucht, die Teilnahmerate[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 15. Deutscher Kongress für Versorgungsforschung
title: Prävalenz von Demenz bei Migranten und Deutschen: Eine vergleichende Analyse anhand von Routinedaten einer deutschen Krankenversicherung
Creators: name: Lorrek, Kristina
name: Simic, Dusan
name: Hein, Rebecca
name: Ihle, Peter
name: Schubert, Ingrid
name: Stock, Stephanie
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: In den 50er und 60er Jahren des letzten Jahrhunderts kamen viele Migranten nach Deutschland. Bis zum jetzigen Zeitpunkt existiert keine Untersuchung zur Prävalenz von Demenz, die ein Augenmerk auf den Unterschied zwischen Deutschen und Migranten gerichtet hat. Fragestellung: Es [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 15. Deutscher Kongress für Versorgungsforschung
Analyse de risques du circuit des préparations aux Hôpitaux universitaires de Strasbourg
Creators: name: Maurer, Claire
name: Dory, Anne
name: Leroy, Maxime
name: Baur, Sylvie
name: Michel, Bruno
name: Gourieux, Bénédicte
Publisher: name: Health & Co
Year: 2021
Subjects: Gestion du risque
Amélioration de la qualité
Circuit du médicament
Système d’information

description: Contexte. Le secteur des préparations médicamenteuses du service pharmacie stérilisation est engagé dans une démarche d’amélioration continue de la qualité et est certifié ISO 9001:2015. Les précédentes analyses de risques effectuées ont conduit, en 2018, au déploiement d’un logiciel de gestion du circuit des préparations médicamenteuses autres que les reconstitutions de chimiothérapies. L’objectif de ce travail a été de réactualiser l’analyse de risques du circuit des préparations suite à son informatisation. Méthodologie. Une nouvelle analyse de risques, basée sur la méthodologie Amdec et intégrant l’informatisation du secteur, a été conduite. Elle a porté sur les différentes étapes du processus de préparation, de l’analyse pharmaceutique de la prescription à l’acheminement de la préparation médicamenteuse au patient. Cette analyse a été comparée à celle conduite en 2014. Résultats et discussion. Lors de la seconde analyse, 16% de modes de défaillance à criticité élevée (N=9) ont été mis en évidence, contre 38% (N=16) en 2014. La préparation des documents et des matériels nécessaires à la réalisation de la préparation est hautement sécurisée par l’informatisation. Les criticités élevées résiduelles font l’objet de mesures dans le cadre d’un plan d’action portant principalement sur l’étape de préparation galénique. Un audit annuel de lavage et de friction hydro-alcoolique des mains a par exemple été mis en place. Conclusion. Cette seconde analyse de risques confirme l’amélioration de la sécurisation du processus des préparations médicamenteuses à la suite de son informatisation et la nécessité d’intégrer en continu les nouveaux risques liés à ce processus.
title:  Le organizzazioni del terzo settore tra managerialità e contributo sociale
Creators: name: Dafano  , Fabrizio
Publisher: name: Roma TrE-Press
Year: 2023

description: Lo sviluppo del Terzo settore è particolarmente significativo per la trasversalità dei servizi e per la declinazione del principio di sussidiarietà, in un sistema socioeconomico progredito e generatore di disparità culturali e sociali. È necessario adoperarsi per un’evoluzione delle competenze professionali, in una prospettiva europea e internazionale. Questo contributo esplora la dimensione culturale, i processi di valorizzazione delle persone e gli stili di managerialità in sintonia con il sistema di valori del TS.

The development of the third sector has proved to be particularly significant for the transversal nature of services and for the implementation of the subsidiarity principle, in a socio-economic system that is as advanced as it is a generator of cultural and social disparities. It is necessary to work towards an evolution of professional skills, in a European and international perspective. This contribute intends to explore the cultural dimension, the processes of enhancing people and the styles of management, in harmony with the TS value system.
description: Idee, processi, prospettive per l’educazione e il terzo settore
Influence of Tumor Site on Survival in Young Patients with Head and Neck Squamous Cell Carcinoma
Creators: name: Steffen, Claudius
name: Piwonski, Iris
name: Heiland, Max
name: Stromberger, Carmen
name: Kofla, Grzegorz
name: Doll, Christian
name: Coordes, Annekatrin
name: Beck-Broichsitter, Benedicta
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: squamous cell carcinoma of head and neck
subject: head and neck neoplasms
subject: survival
subject: young adult
subject: child
subject: cancer
subject: risk factors
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The number of patients under the age of 45 diagnosed with head and neck squamous cell carcinomas (HNSCC) is increasing, probably due to the incidence of oropharyngeal cancers. Comparisons of HNSCC in young and old patients regarding tumor site and survival in sample sizes of relevance are rarely published. The aim of the study was to analyze the differences in survival between age groups dependent on tumor site and the influence of oropharyngeal cancers on the rising rates of HNSCC in the young. The records of 4466 patients diagnosed with HNSCC were reviewed retrospectively. Patients younger than 45 years were divided further into four subgroups for specific age differences in the young. The influences of patient and clinicopathological characteristics on survival were assessed using Kaplan-Meier analyses. Among the patient cohort, 4.8% were younger than 45 years. Overall survival (OS) in these patients was better, with a 5-year OS of 66.1% (vs. 46.4%), while relapse-free survival (RFS) was better in the older patient population, with a 5-year RFS of 74.9% (vs. 68.1%). Decreased RFS in the young was found for advanced tumor stages and tumor sited at the larynx. Hypopharynx and advanced stages were independent risk factors for OS under 45 years. Overall, 44.4% of all HNSCC in patients under 30 years were nasopharyngeal cancers, and incidence decreased with age. The incidence of oropharyngeal cancers increased significantly with age. Better OS in the young may be explained by lower tumor and disease stages, whereas oropharyngeal tumors and HPV were not found to cause rising rates of HNSCC. Laryngeal malignancies in young patients might be related to an increased malignant potential and should, consequently, be treated as such.
A different approach to anisotropic spherical collapse with shear and heat radiation
Creators: name: Ivanov, B. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In order to study the type of collapse, mentioned in the title, we introduce a physically meaningful object, called the horizon function. It directly enters the expressions for many of the stellar characteristics. The main junction equation, which governs the collapse, transforms into a Riccati equation with simple coefficients for the horizon function. We integrate this equation in the geodesic case. The same is done in the general case when one or another of the coefficients vanish. It is shown how to build classes of star models in this formulation of the problem and simple solutions are given.
description: 15 pages, to appear in Int.J.Mod.Phys.D
title: BRIDGE-Health und die European Core Health Indicators (ECHI): Gesundheitsinformationen und -indikatoren in Europa
Creators: name: Fehr, Angela
name: Hense, Sabrina
name: Ziese, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Auf nationaler Ebene sind Gesundheitsdaten und -informationen aus validen und vergleichbaren Quellen Grundlage für eine evidenzbasierte Gesundheitspolitik. Internationale Vergleiche von Daten stellen bis heute ein Problem dar. Grund hierfür ist die Unterschiedlichkeit in der Erhebung,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 15. Deutscher Kongress für Versorgungsforschung
title: Macro DE - Executive Summary - DE2002 / WP2.0: Development of a methodology to calculate energy demand
Creators: name: ETI
Publisher: name: ETI
Year: 2013
Subjects: subject: Distributed Energy
subject: ENERGY EFFICIENCY (Residential and commercial)

description: The objective of the Distributed Energy (DE) Programme is to increase the uptake of DE through the development of integrated systems in order to reduce through-life costs, improve ease of installation and increase efficiency in the combined generation of heat and electricity. Within this programme framework the objective of the Macro DE FRP will develop and validate a software methodology to enable the design of optimised DE solutions where clusters of demand sites are linked with appropriate DE supply equipment.The project will quantify the opportunity for Macro level DE (up to 50MW) in the UK and the potential to accelerate the development of appropriate technology by 2020 for the purposes of significant implementation by 2030

Subsequent to this report it was agreed to purchase CreditSafe’s registered company database due to its better overall accuracy of key indicator data for the tertiary sector.

Having developed and validated a method for forecasting energy demand, the next steps within this particular work package areTo develop an approach for creating around 20 UK “Characteristic Zones” to calculate aggregated zonal demand.Develop an approach for assessing large UK waste heat emittersIn addition with a separate work package (WP4)The consortium will develop a design/optimisation methodology to aggregate zonal energy demand data and design/optimise zonal DE centre’s using the temporal demand profiles from this deliverable together with a library of DE technology/equipment (WP3). This design/optimisation methodology will be embedded in a pre-prototype software too
Level Up Your Strategy: Towards a Descriptive Framework for Meaningful Enterprise Gamification
Creators: name: Ruhi, Umar
Publisher: name: arXiv
Year: 2016
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Gamification initiatives are currently top-of-mind for many organizations seeking to engage their employees in creative ways, improve their productivity, and drive positive behavioural outcomes in their workforce - ultimately leading to positive business outcomes on the whole. Despite its touted benefits, little empirical research has been done to date to investigate technological and individual personal factors that determine the success or failure of enterprise gamification initiatives. In this article, we provide a summary of our preliminary research findings from three case studies of gamification initiatives across different business contexts and present an empirically validated descriptive framework that details the key success factors for enterprise gamification. Our adaptation of the mechanics, dynamics, and aesthetics (MDA) framework for enterprise gamification aims to explicate the connections between end-user motivations, interactive gameplay elements, and technology features and functions that constitute effective gamification interventions in the enterprise. Following a discussion of the core elements in the framework and their interrelationships, the implications of our research are presented in the form of guidelines for the management and design of gamification initiatives and applications. The research findings presented in this article can potentially aid in the development of game mechanics that translate into positive user experiences and foster higher levels of employee engagement. Additionally, our research findings provide insights on key success factors for the effective adoption and institutionalization of enterprise gamification initiatives in organizations, and subsequently help them enhance the performance of their employees and drive positive business outcomes.
description: 12 pages, 3 figure, 2 tables