cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Ð­ÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¶ÐµÑÑÐºÐ¸Ñ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÑ Ð¾Ð´ÐµÐ¶Ð´
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: The effectiveness of the use of concrete road pavement
Creators: name: ÐÐ¾Ð»Ð¸ÐºÐ¾Ð²Ð°, ÐÐ»ÐµÐºÑÐ°Ð½Ð´ÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÐÐ²ÑÐ¾Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½ÑÐµ Ð´Ð¾ÑÐ¾Ð³Ð¸
ÐÐ¾ÑÐ¾Ð¶Ð½ÑÐµ Ð¿Ð¾ÐºÑÑÑÐ¸Ñ Ð°ÑÑÐ°Ð»ÑÑÐ¾-Ð±ÐµÑÐ¾Ð½Ð½ÑÐµ
Ð¶ÐµÑÑÐºÐ¸Ðµ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÐµ Ð¾Ð´ÐµÐ¶Ð´Ñ
ÑÐµÐ¼ÐµÐ½ÑÐ¾Ð±ÐµÑÐ¾Ð½Ð½ÑÐµ Ð´Ð¾ÑÐ¾Ð³Ð¸
Ð²Ð¸Ð±ÑÐ¾ÑÐºÐ°ÑÑÐ²Ð°ÐµÐ¼ÑÐ¹ Ð±ÐµÑÐ¾Ð½
ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ°Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÑ
concrete road pavement
cement concrete roads
vibro-plastered concrete
economic efficiency

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐµ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð¸ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÑ Ð¾Ð´ÐµÐ¶Ð´ Ð¸Ð· ÑÐµÐ¼ÐµÐ½ÑÐ¾Ð±ÐµÑÐ¾Ð½Ð°. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÐ½Ð°Ð»Ð¸Ð· ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ð° ÑÐµÐ¼ÐµÐ½ÑÐ¾Ð±ÐµÑÐ¾Ð½Ð½ÑÑ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÑ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ñ Ð² ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ðµ Ð°Ð²ÑÐ¾Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½ÑÑ Ð´Ð¾ÑÐ¾Ð³; 2. ÐÐ·ÑÑÐµÐ½Ð¸Ðµ Ð¼Ð¸ÑÐ¾Ð²Ð¾Ð³Ð¾ Ð¾Ð¿ÑÑÐ° Ð¿Ð¾ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¶ÐµÑÑÐºÐ¸Ñ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÑ Ð¾Ð´ÐµÐ¶Ð´; 3. ÐÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ñ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¶ÐµÑÑÐºÐ¸Ñ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÑ Ð¾Ð´ÐµÐ¶Ð´ Ð² ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¼ ÑÑÑÐ¾Ð¸ÑÐµÐ»ÑÑÑÐ²Ðµ; 4. ÐÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ ÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÐ¸ ÑÑÐ°ÑÑÐºÐ¾Ð² Ð°Ð²ÑÐ¾Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½ÑÑ Ð´Ð¾ÑÐ¾Ð³ Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ ÑÐ°Ð·Ð½ÑÑ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹; 5. ÐÑÐµÐ½ÐºÐ° ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ð¹ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¶ÐµÑÑÐºÐ¸Ñ Ð´Ð¾ÑÐ¾Ð¶Ð½ÑÑ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹.
description: The subject of the graduate qualification work is Â«The effectiveness of the use of concrete road pavementÂ». This work is devoted to the assessment of the economic and operational efficiency of cement concrete pavement. Tasks that were solved in the course of the study: 1. Analysis of existing technologies for the construction of cement-concrete road surfaces that can be used in the construction of automobile roads; 2. Study of the world experience in the implementation of the use of rigid road clothes; 3. Problems and prospects of using rigid road coverings in modern construction; 4. Determining the cost of road sections using different technologies; 5. Assessment of the economic efficiency of the use of rigid road surfaces.
Sesquiterpenes from Curcuma wenyujin with their inhibitory activities on nitric oxide production in RAW 264.7 cells
Creators: name: Suyu Gao
name: Guiyang Xia
name: Liqing Wang
name: Zhou, Li
name: Zhao, Feng
name: Huang, Jian
name: Lixia Chen
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: One new sesquiterpene, 7α,11-epoxy-6α-hydroxy-carabrane-4,8-dione, along with 10 known ones were isolated from the essential oil of Curcuma wenyujin Y.H. Chen et C. Ling. Their structures were established based on extensive spectroscopic analysis. The absolute configuration of compound 1 was determined by the CD analysis of the insitu formed [Rh2(OCOCF3)4] complex, and the CD data analysis based on the octane rule of cyclohexanone. The inhibitory effects of these sesquiterpenes on nitric oxide production in lipopolysaccharide-activated macrophages were also evaluated. Furthermore, the biosynthesis pathway of the isolated compounds was proposed.
title: Liste de mots en jarai occidental lue par une locutrice née à Kaning en 1997
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Western Jarai
subject: jra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site
Creators: name: Masini, Tiziana
name: Birkaya, Barbara
name: Dijk, Simon Van
name: Milon Mondal
name: Hekelaar, Johan
name: Jäger, Manuel
name: Scheltinga, Anke C. Terwisscha Van
name: Mulchand S. Patel
name: Hirsch, Anna K. H.
name: Moman, Edelmiro
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 60506 Virology

description: The last decade has witnessed the reawakening of cancer metabolism as a therapeutic target. In particular, inhibition of pyruvate dehydrogenase kinase (PDK) holds remarkable promise. Dichloroacetic acid (DCA), currently undergoing clinical trials, is a unique PDK inhibitor in which it binds to the allosteric pyruvate site of the enzyme. However, the safety of DCA as a drug is compromised by its neurotoxicity, whereas its usefulness as an investigative tool is limited by the high concentrations required to exert observable effects in cell culture. Herein, we report the identification – by making use of saturation-transfer difference NMR spectroscopy, enzymatic assays and computational methods – of furoate and thenoate derivatives as allosteric pyruvate-site-binding PDK2 inhibitors. This work substantiates the pyruvate regulatory pocket as a druggable target.
Miranda (Mário de França), Libertados para a práxis da Justiça (A Teologia da Graça no actual contexto latino-americano), coleção Fé e Realidade, S. Paulo, Ed. Loyola, 1980, 190 p.
Creators: name: Pinho, Arnaldo De
Publisher: name: Humanística e Teologia
Year: 1981

description: Humanística e Teologia, v. 2 n. 1 (1981)
title: Liste de mots en jarai occidental lue par une locutrice née à Kaning en 1965
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Western Jarai
subject: jra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
RAQAMLI O'YINLAR VA UNING TA'LIM TIZIMIDAGI O'RNI
Creators: name: Oʻrinboyeva, Kumushoy
name: Abdusattarova, Mahliyo
name: Abduqahharova, Zilola
name: Yoqubjonova, Muazzamoy
Publisher: name: Zenodo
Year: 2025

description: Bir sohani rivojlantirish uchun ilmiy yondashuv kerak. Buning uchun xodimlarning bilim va dunyoqarashini oshirish zarur. Bu esa o'qitishda yangicha yondashuvlarni ilgari surish, o'qitishda innovatsion texnologiyalardan foydalanishni taqozo etadi. Ushbu maqola maktab fanlarini o'qitish, o'quvchilar tafakkurini rivojlantirishda raqamli (kompyuter va mobil) o'yinlarning ahamiyati haqida ma'lumot berilgan. Fanlarni o'qitishda yuzaga keladigan muammolar, ularni bartaraf etishda o'yinlarning roliga alohida e'tibor qaratilgan. Shuningdek, maqolada o’quvchilarni o'qitishda raqamli o'yinlardan foydalanish samarasi tasvirlangan.
Gender differences in effects of obesity and asthma on adolescent lung function: Results from a population-based study
Creators: name: Chen, Yi-Chun
name: Huang, Yu-Li
name: Ho, Wen-Chao
name: Wang, Yu-Chun
name: Yang-Hao Yu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Objective: To investigate lung function associated with asthma and body mass index (BMI) among adolescents at 96 northern Taiwan junior high schools participating in an asthma screening program. Methods: The questionnaires and lung function test results measured for 3669 boys and 3523 girls were included in this study for data analysis. Measures of forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1) and FEV1/FVC ratio were compared by sex, asthma status and BMI. Results: Overall mean FVC levels were similar between students with and without asthma, 3.71 L vs. 3.71 L for boys (p = 0.991) and 2.79 vs. 2.78 for girls (p = 0.517). The overall mean FEV1 levels were also similar between girls with and without asthma. Asthmatic boys had lower FEV1 than non-asthmatic boys. Mean FEV1/FVC was significantly lower in students with asthma than those without asthma. Mean FVC and FEV1 increased with BMI in both sexes. A lower mean FEV1/FVC was observed among students with asthma and high BMI, and was more pronounced in boys than in girls. Multivariable regression analysis also showed that FEV1/FVC ratios were negatively associated with asthma and high BMI, stronger in boys than in girls for asthma (β = −2.176 (standard errors (SE) = 0.268) vs. −1.085 (SE = 0.258) and for BMI (β = −0.309 (SE = 0.025) vs. −0.218 (SE = 0.029)). Conclusion: This northern Taiwan study suggests that FEV1/FVC is negatively associated with asthma and high BMI in adolescents, stronger for boys than for girls.
title: Liste de mots en jarai occidental lue par une locutrice née à Kaning en 1978
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Western Jarai
subject: jra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Romano-British Horningsea Ware kilns at 12 Pieces Lane, Waterbeach, Cambridgeshire
Creators: name: Newton, Andrew A S
name: Peachey, Andrew
Publisher: name: Archaeology Data Service
Year: 2015

description: Proceedings of the Cambridge Antiquarian Society, 101, 143-160
description: Excavation at 12 Pieces Lane, Waterbeach, undertaken by Archaeological Solutions in 2010, revealed two Romano-British pottery kilns of the Horningsea ware industry. These kilns add to the corpus of information regarding this industry in Cambridgeshire and increase understanding of the character of the industry and the sites at which this pottery was produced. Evidence from these kilns indicates that kiln form varied between the Horningsea production sites. The pottery assemblage recovered suggests that Horningsea ware production had begun in Waterbeach by the early 2nd century AD, earlier than previously thought. Evidence to indicate that earlier kilns may have existed at the site was recorded and this, coupled with the dateable evidence, suggests that the layout of the site was altered repeatedly with kilns being built, demolished and rebuilt several times over in approximately the same locations. The discovery of a small number of Iron Age pits of the 3rd to 1st century BC, along with notable concentrations of residual Iron Age pottery, suggested that there may have been a significant level of Iron Age activity at or close to this location which may have been almost completely obscured by the fairly intense Roman activity that eventually succeeded it.
Genetic structure in two Phascolosoma species in the Pacific Ocean
Creators: name: Johnson, Nathan D.
name: Schulze, Anja
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Phascolosoma agassizii, a commonly reported species of sipunculan worm, occurs at various depths throughout the north Pacific. However, previous studies have shown that this nominal species is actually comprised of two genetically divergent lineages. Phascolosoma agassizii is isolated to the eastern Pacific, whereas a second species, here referred to Phascolosoma sp., is located in the western Pacific and represents a unique, non-sister taxon to P. agassizii. Both species exhibit the same developmental mode with a long-lived, planktotrophic, pelagosphera larval stage, which may facilitate long-distance dispersal, although developmental timing differs. Using an inter-simple sequence repeat polymerase chain reaction (ISSR-PCR) genetic fingerprinting approach, this study examines non-coding polymorphic regions of the nuclear genomes of P. agassizii from four eastern Pacific populations and of Phascolosoma sp. from six western Pacific locations. Small-scale spatial genetic variation was analysed separately for each coastline using an Analysis of Molecular Variance. The data pointed to the potential presence of fine-scale genetic structure within P. agassizii, and recovered significant genetic structure within Phascolosoma sp. from the western Pacific. This study shows that ISSR-PCR is a relatively fast and cost-effective way to study fine-scale genetic diversity in marine invertebrates, although possible analyses and interpretations of the data are subject to the same limitations as other size polymorphism-based approaches.
Low genetic diversity and lack of genetic structure in the giant jellyfish Nemopilema nomurai in Chinese coastal waters
Creators: name: Zhijun Dong
name: Zhongyuan Liu
name: Dongyan Liu
name: Qingqing Liu
name: Tingting Sun
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The giant jellyfish Nemopilema nomurai is a scyphozoan species well-known in East Asian Marginal Seas for its damage to fisheries. The genetic diversity and population structure of N. nomurai, collected from five geographic regions in Chinese coastal seas, were examined based on mitochondrial cytochrome c oxidase subunit I (COI) gene and nuclear internal transcribed spacer one (ITS1) sequences. A total of 26 and five unique haplotypes were recovered from the COI and ITS1 genes, respectively. The overall genetic diversity of N. nomurai calculated by the COI and ITS1 sequences was low (haplotype diversity 0.727% and 0.108%, nucleotide diversity 0.212% and 0.039%). The median-joining network analysis revealed a star-like haplotype network. The hierarchical Analysis of Molecular Variance (AMOVA) of COI haplotypes showed that N. nomurai populations form a single population, with a low FST (0.0149, p = 0.1036). The dispersal ability, together with the biological characteristics, could be important factors for the lack of a geographically structured pattern in N. nomurai in Chinese coastal waters.
Multicomponent reactions for the synthesis of new cyclopentadienephosphonate derivatives in water
Creators: name: Sheikholeslami-Farahani, Fatemeh
name: Daryoush Zareyee
name: Mohammadi, Marziyeh
name: Mahboubeh Ghasemian
name: Soltani, Samira
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A series of polysubstituted cyclopentadienephosphonate derivatives were synthesized via one-pot multicomponent reactions of primary amines and phosphites with activated acetylenic compounds in water as the solvent at room temperature. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and a straightforward procedure.
Development and application of a simultaneous measurement method for gaseous ammonia and particulate ammonium in ambient air
Creators: name: Huy, Duong Huu
name: Thanh, Le Tu
name: Hien, To Thi
name: Norimichi Takenaka
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Ammonia gas is one of the precursors contributing to the formation of secondary particulate ammonium via reactions with atmospheric acids, such as sulfuric and/or nitric acids, which are present in ambient air. In this study, a new instrument that is suitable for measuring ammonia gas and fine particulate ammonium (PM2.5 NH4+) concentrations simultaneously under ambient conditions was developed. A wetted frit sampler was connected in the back of a counter-current flow tube (CCFT) sampler, and the NH3 gas and PM2.5 NH4+ samples were collected by CCFT and wetted frit samplers, respectively. An air sample was drawn through the samplers at a flow rate of 1.0 dm3 min−1 and an absorption water flow rate of 120 mm3 min−1. Then, the ammonium that formed in the absorption solution was detected by the indophenol method using a continuous flow analysis system. The estimated detection limits were 43 and 49 ng m−3 for ammonia gas and PM2.5 NH4+, respectively. Notably, the ammonia gas was collected on the CCFT sampler with a collection efficiency of 98.5%, but most of the PM2.5 NH4+ passed through it and was captured on the wetted frit sampler with a collection efficiency of approximately 100%. The present method was applied to measure NH3 gas and PM2.5 NH4+ at two urban sites: Osaka, Japan and Ho Chi Minh City, Vietnam. It was found that the simultaneous measurement method performed very well and that the measured concentrations were comparable with those obtained with the annular denuder method. Copyright © 2016 American Association for Aerosol Research
Plain language summary of publication: Vertigoheel improves the brain’s ability to compensate vertigo
Creators: name: Duller, Stephan
name: Weyer, Kathrin
name: Chabbert, Christian
Publisher: name: Heel GmbH
Year: 2024
Subjects: classificationCode: 3209
subject: Neurosciences
subject: FOS: Clinical medicine
classificationCode: 320903
subject: Central nervous system
classificationCode: 3214
subject: Pharmacology and pharmaceutical sciences

description: This is a plain language summary of a published peer-reviewed article in English, German, Spanish and Russian. It refers to a preclinical study investigating Vertigoheel’s effect on central vestibular compensation after peripheral vestibulopathy in rats. This summary was not peer-reviewed but it represents the opinions of the authors. For a full list of declarations, including funding and author disclosure statements, please read the full open-access article online.
Vicente E. Y Tarancón - Marcelo González - Narciso Jubany, Iglesia y Política en la España de hoy, (prólogo e introdução de Olegario González de Cardedal), Salamanca, Ed. Sígueme, vol. 210x130, 143 pp.
Creators: name: Pinho, Arnaldo De
Publisher: name: Humanística e Teologia
Year: 1981

description: Humanística e Teologia, v. 2 n. 1 (1981)
Changing and increasing biosecurity risks to food and nutrition security
Creators: name: Robinson, Andrew
name: Robinson, Andrew
Publisher: name: Unknown
Year: 2021
Subjects: Food Security and Poverty

description: Australia’s biosecurity system protects us and the things we care about – including agriculture and the economy, animal and plant health, the environment and social amenity, and human health – from invasive pests. The nature of the risk from invasive pests is constantly changing, and almost invariably increasing, so the biosecurity system becomes ever more important. But what is the system? How does it work, and will it work the same way in the future? What is our role in it – and how can we best support it? Surely, it’s all someone else’s problem? This overview presentation will review the current and future impacts of emerging biosecurity threats to plant and animal production and human health and biodiversity. The four speakers in this session will pull out trends in the emergence and spread of plant and zoonotic diseases and identify key factors that both promote and reduce disease spread. We will tease out the threats to food security, nutrition and human health that arise from inadequate biosecurity understanding and management, and show how phytosanitary control and best-practice management can materially reduce biosecurity risks for the land-manager and the landscape. The biosecurity system is no longer just AQIS standing steadfast at the border, and perhaps it never was really that simple. But we need to change the way we think about biosecurity as a system of organisations, as a regulatory framework, and as an outcome. The increasing interconnectedness of consumers and international markets means that we are now all stakeholders of and participants in the biosecurity system. Changing trade patterns, changing global alliances, and changing climate all press us to think and act today! How will we get there?
title: Liste de mots en jarai occidental lue par un locuteur né à Kaning en 1965
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Western Jarai
subject: jra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Dois casos de translação da filosofia de expressão árabe no Portugal medieval: João de Sevilha e de Lima e Afonso Dinis de Lisboa (no oitavo centenário da morte de Averróis)
Creators: name: Carvalho, Mário Santiago De
Publisher: name: Humanística e Teologia
Year: 1999

description: Humanística e Teologia, v. 20 n. 2-3 (1999)
title: France, the War and the Vote
title: French Europeans Head to the Ballot Box  as Ukrainians Fight for Freedom: How Will the War Shape their Vote?
titleType: Subtitle
Creators: name: Hoffmann, Isabell
name: de Vries, Catherine E.
Publisher: name: Bertelsmann Stiftung
publisherIdentifier: https://ror.org/01wj9hk44
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Europeans
Public Opinion
France
Ukraine
Russia
European Union

description: Russia’s full-scale invasion of Ukraine has had a profound impact on EU policies and politics. The European Union and its member states have steadfastly supported Ukraine in its defensive efforts while simultaneously aiming to curb Russia’s aggression. This support has been manifested through unprecedented financial and economic sanctions imposed on Russia and its principal actors, as well as the provision of weapons and financial assistance to Ukraine. EU member states have also opened their doors to Ukrainian refugees, and Ukraine, once a distant neighbour, is now actively pursuing accession to become a full EU member.

Driven by pivotal events, this strategic shift and accelerated decision-making have gained widespread public support. However, in recent months, we have observed an emerging decline in this support as the war enters its third year and other crises become apparent – developments that are redirecting public attention and sensitivities.

The timing of these shifts is of particular significance, as they coincide with the crucial re-election of European leadership in 2024. As EU citizens prepare to cast their votes for a new European Parliament in June, closely followed by the nomination of a new European Commission, this publication seeks to provide a deeper understanding of how policies on Ukraine intersect with political orientations and party preferences.

In this country report "France, the War and the Vote", we explore the relationship between political party preferences in France and seven key Ukraine-related policy questions:

Does the European Union need a common defence policy?
Should the EU support Ukraine by delivering weapons?
Should your country accept refugees from Ukraine?
Should the EU accept Ukraine as a member state in the coming years?
Should the EU become more energy independent of Russia even if that means prices are rising even further?
Do you think economic and financial sanctions on Russia are effective or ineffective?
Do you think the reconstruction of Ukraine will be an economic opportunity or an economic burden?
Development and Application of a Simultaneous Measurement Method for Gaseous Ammonia and Particulate Ammonium in Ambient Air
Creators: name: Huy, Duong Huu
name: Thanh, Le Tu
name: Hien, To Thi
name: Norimichi Takenaka
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Physiology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Ammonia gas is one of the precursors contributing to the formation of secondary particulate ammonium via reactions with atmospheric acids, such as sulfuric and/or nitric acids, which are present in ambient air. In this study, a new instrument that is suitable for measuring ammonia gas and fine particulate ammonium (PM2.5 NH4+) concentrations simultaneously under ambient conditions was developed. A wetted frit sampler was connected in the back of a counter-current flow tube (CCFT) sampler, and the NH3 gas and PM2.5 NH4+ samples were collected by CCFT and wetted frit samplers, respectively. An air sample was drawn through the samplers at a flow rate of 1.0 dm3 min−1 and an absorption water flow rate of 120 mm3 min−1. Then, the ammonium that formed in the absorption solution was detected by the indophenol method using a continuous flow analysis system. The estimated detection limits were 43 ng m−3 and 49 ng m−3 for ammonia gas and PM2.5 NH4+, respectively. Notably, the ammonia gas was collected on the CCFT sampler with a collection efficiency of 98.5 %, but most of the PM2.5 NH4+ passed through it and was captured on the wetted frit sampler with a collection efficiency of approximately 100 %. The present method was applied to measure NH3 gas and PM2.5 NH4+ at two urban sites: Osaka, Japan and Ho Chi Minh City, Vietnam. It was found that the simultaneous measurement method performed very well and that the measured concentrations were comparable with those obtained with the annular denuder method.
Microwave-assisted neat synthesis of α-aminophosphonate/phosphinate derivatives of 2-(2-aminophenyl)benzothiazole as potent antimicrobial and antioxidant agents
Creators: name: Shaik Thaslim Basha
name: Hasti Sudhamani
name: Rasheed, Syed
name: Nagam Venkateswarlu
name: Tartte Vijaya
name: Chamarthi Naga Raju
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: A series of diethyl/ethylphenyl {2-(benzo[d]thiazol-2-yl)phenylamino}phosphonates and phosphinates were synthesized under microwave irradiation and neat conditions via Kabachnik-Fields reaction in high yields (80%–93%). The compounds were screened for antimicrobial and antioxidant properties. A few compounds showed effective antibacterial and antifungal activities at MIC value 12.5 μg/mL as compared with the standard at MIC value 6.25 μg/mL.
Strain selection, growth productivity and biomass characterization of novel microalgae isolated from fresh and wastewaters of upper Punjab, Pakistan
Creators: name: Gill, Saba Shahid
name: Mehmood, Muhammad Aamer
name: Niaz Ahmad
name: Ibrahim, Muhammad
name: Umer Rashid
name: Shafaqat Ali
name: Imededdine Arbi Nehdi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The present study was focussed on selection of fast-growing microalgae with higher lipid content using cheaper growth media, aimed to reduce the cost of algal biomass production. Samples were collected from 40 different sites from fresh and wastewater bodies. Based on morphological differences, two microalgae (SSG and SA) from wastewater and three (OP, DFM and JRC) from fresh water habitat were selected for further characterization. The specific growth rates (g Day −1 L−1) of the OP, DFM, JRC, SA and SSG were found to be 0.614, 0.638, 0.734, 1.06 and 1.02, respectively, whereas the doubling time (Td) was shown to be as 39.30, 36.48, 22.08, 12.24 and 12.98 h, respectively, when cultured without controlled temperature and CO2 supply, in a locally designed photobioreactor. All five microalgae shown considerable growth at a range of pH 6.0–9.0 with a peak activity within pH range 7.5–8.5. The OP, DFM and JRC contained 27%, whereas SSG and SA shown 39% lipid content. The phylogenetic analyses based on the 18S rRNA gene sequence have shown that studied microalgal strains may be novel species.
Introduction of secondary pyridyl-1H-tetrazole derivatives into Keggin–Ag–(1,10-phenanthroline) system for tuning dimensionalities and architectures: assembly and properties
Creators: name: Xiuli Wang
name: Tianjiao Li
name: Aixiang Tian
name: Xu, Na
name: Zhang, Rui
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: By introducing three pyridyl-1H-tetrazole derivatives to Keggin–Ag-(1,10-phenanthroline) system, five new polyoxometalate-based inorganic–organic hybrid compounds with different dimensionalities and structures, [Ag3(4-ptz)2Na(phen)(HPMo12O40)]·2H2O (1), [Ag4(3-ptz)2(phen)2(HPMo12O40)] (2), [Ag4(3-ptz)2(phen)2(HVW12O40)] (3), [Ag3(3-bptzb)(phen)2(PMo12O40)] (4) and [Ag3(3-bptzb)(phen)2(VW12O40)] (5) (phen = 1,10-phenanthroline, x-ptzH = 5-(x-pyridyl)-1H-tetrazole (x = 3, 4), 3-bptzb = 1,4-bis(5-(3-pyridyl)-tetrazolyl)butane), have been synthesized under hydrothermal conditions. Compound 1 is a 1-D belt architecture constructed from an Ag-4-ptz metal–organic chain and two Ag–PMo12O40–Na–phen inorganic–organic chains. When 3-ptzH was introduced as secondary ligand in 2 and 3 instead of 4-ptzH, two isostructural architectures were obtained, which contain a 1-D zigzag Ag-3-ptz chain with phen ligands hanging on both sides of the chain. The Keggin anions connect adjacent Ag-3-ptz chains to construct 2-D networks. When the flexible 3-bptzb was selected, isostructural 4 and 5 with 2-D networks were obtained, which were constructed from binuclear subunits and Keggin–Ag inorganic chains. The influence of three pyridyl-1H-tetrazole derivatives as secondary ligands on the dimensionalities and architectures of 1–5 was discussed. The electrochemical and photocatalytic properties of the compounds were investigated.
title: Liste de mots en jarai occidental lue par une locutrice née à Kaning en 1973
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Western Jarai
subject: jra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Introduction of secondary pyridyl-1H-tetrazole derivatives into Keggin-Ag-(1,10-phenanthroline) system for tuning dimensionalities and architectures: Assembly and properties
Creators: name: Xiuli Wang
name: Tianjiao Li
name: Aixiang Tian
name: Xu, Na
name: Zhang, Rui
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: By introducing three pyridyl-1H-tetrazole derivatives to Keggin-Ag-(1,10-phenanthroline) system, five new polyoxometalate (POM)-based inorganic-organic hybrid compounds with different dimensionalities and structures, [Ag3(4-ptz)2Na(phen)(HPMo12O40)]·2H2O (1), [Ag4(3-ptz)2(phen)2(HPMo12O40)] (2), [Ag4(3-ptz)2(phen)2(HVW12O40)] (3), [Ag3(3-bptzb)(phen)2(PMo12O40)] (4) and [Ag3(3-bptzb)(phen)2(VW12O40)] (5) (phen = 1,10-phenanthroline, x-ptzH = 5-(x-pyridyl)-1H-tetrazole (x=3,4), 3-bptzb = 1,4-bis(5-(3-pyridyl)-tetrazolyl)butane), have been synthesized under hydrothermal conditions. Compound 1 is a one dimension (1D) belt architecture constructed from an Ag-4-ptz metal-organic chain and two Ag-PMo12O40-Na-phen inorganic-organic chains. When 3-ptzH was introduced as secondary ligand in 2 and 3 instead of 4-ptzH, two isostructural architectures were obtained, which contain a 1D zigzag Ag-3-ptz chain with phen ligands hanging on both sides of the chain. The Keggin anions connect adjacent Ag-3-ptz chains to construct 2D networks. When the flexible 3-bptzb was selected, isostructural 4 and 5 with 2D networks were obtained, which are constructed from binuclear subunits and Keggin-Ag inorganic chains. The influence of three pyridyl-1H-tetrazole derivatives as secondary ligands on the dimensitionality and architectures of 1-5 was discussed. The electrochemical and photocatalytic properties of the compounds were investigated.
Modeling Regression Quantile Process Using Monotone B-Splines
Creators: name: Yuan, Yuan
name: Chen, Nan
name: Shiyu Zhou
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Quantile regression as an alternative to conditional mean regression (i.e., least-square regression) is widely used in many areas. It can be used to study the covariate effects on the entire response distribution by fitting quantile regression models at multiple different quantiles or even fitting the entire regression quantile process. However, estimating the regression quantile process is inherently difficult because the induced conditional quantile function needs to be monotone at all covariate values. In this article, we proposed a regression quantile process estimation method based on monotone B-splines. The proposed method can easily ensure the validity of the regression quantile process and offers a concise framework for variable selection and adaptive complexity control. We thoroughly investigated the properties of the proposed procedure, both theoretically and numerically. We also used a case study on wind power generation to demonstrate its use and effectiveness in real problems. Supplementary materials for this article are available online.
Edible black ant smith (Carebara vidua) as human food - A systematic review
Creators: name: Siddiqui, S.A.
name: Ho, L.-H.
name: Adimulam, S.C.
name: Nagdalian, A.
name: Yudhistira, B.
name: Castro-Muñoz, R.
name: Ibrahim, S.A.
Publisher: name: Brill Online
Year: 2024
Subjects: classificationCode: 309999
subject: Other agricultural, veterinary and food sciences not elsewhere classified

description: Meeting food security is one of the major global challenges to ensure sufficient supply of food for current and future generations, considering increasing population growth and climate change issues. Consequently, the consumption of edible insects as an alternative food source has recently gained global attention for combating global food insecurity. The present review aims to provide information on the recent progress in consumption of edible black ant Smith, particularly Carebara vidua, as the main focus. The global consumption record of edible black ant Smith and consumer acceptance as well as the strategies used to increase consumer acceptance of eating edible black ant smith were proposed. In addition, the bioecology of black ant Smith was covered in this review. Further, details are provided in this review on the benefits to health, economy, and environment of practicing eating edible insects such as black ant Smith. Focus on the potential uses of Carebara vidua as a food ingredient in culinary cuisine and their safety concerns from rearing until processing were highlighted. The SCOPUS database was analysed using bibliometric software to understand the connections between recent scientific outputs and ant as human food thoroughly. BioRender software was used to create scientific figures. It is noteworthy to highlight that black ant smith contains high protein and micronutrient, especially iron and zinc are higher than that of plant-, animal-based food, and seafood that contribute significantly to meeting the daily protein and mineral intake amount for human. Moreover, the exhibition of antimicrobial and antioxidant properties of edible black ant smith suggests that it can be used as a future functional ingredients for food, pharmaceutical, and cosmetics purposes. Hence, edible black ant smith is promising as an alternative and potential source of food or medicine for sustainable food security.
Modelling Regression Quantile Process Using Monotone B-splines
Creators: name: Yuan, Yuan
name: Chen, Nan
name: Shiyu Zhou
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Quantile regression as an alternative to conditional mean regression (i.e., least square regression) is widely used in many areas. It can be used to study the covariate effects on the entire response distribution by fitting quantile regression models at multiple different quantiles or even fitting the entire regression quantile process. However, estimating the regression quantile process is inherently difficult because the induced conditional quantile function needs to be monotone at all covariate values. In this paper, we proposed a regression quantile process estimation method based on monotone B-splines. The proposed method can easily ensure the validity of the regression quantile process, and offers a concise framework for variable selection and adaptive complexity control. We thoroughly investigated the properties of the proposed procedure, both theoretically and numerically. We also used a case study on wind power generation to demonstrate its use and effectiveness in real problems. This paper has supplementary materials.
title: Liste de mots en jarai occidental lue par un locuteur né à Kaning en 1952
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Western Jarai
subject: jra

description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Lifted Brownian Kriging Models
Creators: name: Plumlee, Matthew
name: Apley, Daniel W.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Gaussian processes have become a standard framework for modeling deterministic computer simulations and producing predictions of the response surface. This article investigates a new covariance function that is shown to offer superior prediction compared to the more common covariances for computer simulations of real physical systems. This is demonstrated via a gamut of realistic examples. A simple, closed-form expression for the covariance is derived as a limiting form of a Brownian-like covariance model as it is extended to some hypothetical higher-dimensional input domain, and so we term it a lifted Brownian covariance. This covariance has connections with the multiquadric kernel. Through analysis of the kriging model, this article offers some theoretical comparisons between the proposed covariance model and existing covariance models. The major emphasis of the theory is explaining why the proposed covariance is superior to its traditional counterparts for many computer simulations of real physical systems. Supplementary materials for this article are available online.
Pharmacotherapy in pediatric epilepsy: from trial and error to rational drug and dose selection – a long way to go
Creators: name: Dijkman, Sven C. Van
name: Alvarez-Jimenez, Ricardo
name: Danhof, Meindert
name: Pasqua, Oscar Della
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Introduction: Whereas ongoing efforts in epilepsy research focus on the underlying disease processes, the lack of a physiologically based rationale for drug and dose selection contributes to inadequate treatment response in children. In fact, limited information on the interindividual variation in pharmacokinetics and pharmacodynamics of anti-epileptic drugs (AEDs) in children drive prescription practice, which relies primarily on dose regimens according to a mg/kg basis. Such practice has evolved despite advancements in pediatric pharmacology showing that growth and maturation processes do not correlate linearly with changes in body size. Areas covered: In this review we aim to provide 1) a comprehensive overview of the sources of variability in the response to AEDs, 2) insight into novel methodologies to characterise such variation and 3) recommendations for treatment personalisation. Expert opinion: The use of pharmacokinetic-pharmacodynamic principles in clinical practice is hindered by the lack of biomarkers and by practical constraints in the evaluation of polytherapy. The identification of biomarkers and their validation as tools for drug development and therapeutics will require some time. Meanwhile, one should not miss the opportunity to integrate the available pharmacokinetic data with modeling and simulation concepts to prevent further delays in the development of personalised treatments for pediatric patients.
Pharmacotherapy in pediatric epilepsy: from trial and error to rational drug and dose selection – a long way to go
Creators: name: Dijkman, Sven C. Van
name: Alvarez-Jimenez, Ricardo
name: Danhof, Meindert
name: Pasqua, Oscar Della
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Introduction: Whereas ongoing efforts in epilepsy research focus on the underlying disease processes, the lack of a physiologically based rationale for drug and dose selection contributes to inadequate treatment response in children. In fact, limited information on the interindividual variation in pharmacokinetics and pharmacodynamics of anti-epileptic drugs (AEDs) in children drive prescription practice, which relies primarily on dose regimens according to a mg/kg basis. Such practice has evolved despite advancements in pediatric pharmacology showing that growth and maturation processes do not correlate linearly with changes in body size. Areas covered: In this review we aim to provide 1) a comprehensive overview of the sources of variability in the response to AEDs, 2) insight into novel methodologies to characterise such variation and 3) recommendations for treatment personalisation. Expert Opinion: The use of pharmacokinetic-pharmacodynamic principles in clinical practice is hindered by the lack of biomarkers and by practical constraints in the evaluation of polytherapy. The identification of biomarkers and their validation as tools for drug development and therapeutics will require some time. Meanwhile, one should not miss the opportunity to integrate the available pharmacokinetic data with modeling and simulation concepts to prevent further delays in the development of personalised treatments for pediatric patients.
Effects of Soil Characteristics on Spring-Harvested Switchgrass Biomass Composition
Creators: name: Delaquis, Erik
name: Seguin, Philippe
name: Mustafa, Arif F.
name: Samson, Roger
name: Martel, Huguette
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences

description: Switchgrass (Panicum virgatum L.) is a promising bioenergy crop for temperate regions. Overwintering has been used to improve biomass quality, resulting in a more efficient combustion, partially due to a reduction in minerals concentration. This study examines the effects of soil composition on overwintered switchgrass composition. Samples were collected in the spring from 58 environments in Southern Quebec to determine possible relationships between soil composition and biomass quality. Principal component analysis and stepwise regressions were used to identify relationships between soil and biomass compositions. Soil parameters monitored explained 74% of the variation in biomass silicon (Si) concentration, 45% of the variation in ash, and 32% of the variation in magnesium (Mg). Soil composition had limited effects on the concentration of other elements in switchgrass biomass. Switchgrass biomass quality is influenced by soil composition and appears well suited to biomass combustion when overwintered and harvested in the spring.