cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Re/construction d'identités transatlantiques dans les ouvrages littéraires et cinématographiques de Fabienne Kanor
Creators: name: Gonzalez Perez, Maria
Publisher: name: Georgia State University
Year: 2019

description: Ce projet de recherche offre une étude sur la construction des identités transatlantiques dans les œuvres de Fabienne Kanor. Se concentrant sur les films Des pieds mon pied (2009), La noiraude (2005), Jambé dlo (2009), et les romans D'eaux douces (2004) et Humus (2006) nous proposons de parcourir les problèmes rencontrés et les outils utilisés par les personnages, les acteurs, et Kanor elle-même. Ces questions de construction identitaire englobent la langue, le langage, la parole et l’écriture. Ces travaux démontrent comment l’entre deux et le sentiment d’appartenance compliquent la quête identitaire qui semble irrémédiablement butter contre les effets du colonialisme, de la traite négrière, ainsi que de la culture du silence et de la soumission qu’ils impliquent. Cette thèse explore ainsi les conflits qui bousculent la re/construction et la réappropriation du corps et de sa sexualité.
นโยบายและการบริหารจัดการท้องถิ่นบนฐานของทุนทางสังคม : ทางเลือกการพัฒนาท้องถิ่นในศตวรรษที่ 21
Creators: name: ปิยะพงษ์ บุษบงก์
name: สุนทรชัย ชอบยศ
Publisher: name: คณะสังคมศาสตร์ มหาวิทยาลัยนเรศวร
Year: 2558
Subjects: ทุนทางสังคม,นโยบายและการบริหารจัดการท้องถิ่น

description: 1, 11, วารสารสังคมศาสตร์ มหาวิทยาลัยนเรศวร
GLYCATION ABOLISHES THE CARDIOPROTECTIVE EFFECTS OF ALBUMIN DURING ISCHEMIA-REPERFUSION
Creators: name: Essop, M.Faadiel
name: Mapanga, Rudo
name: Joseph, Danzil
name: Boyer, Florence
name: Bourdon, Emmanuel
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Although albumin can exert therapeutic effects, diabetes can trigger modifications e.g. advanced glycation end products (AGE) that are associated with cardiovascular complications (1). We therefore hypothesized that albumin glycation results in loss of its cardioprotective properties during ischemia-reperfusion under conditions simulating acute hyperglycemia. Rat hearts were divided into 6 groups: control (11 mM glucose) +/- native bovine serum albumin (BSA) or glycated BSA (BSAgly); and high glucose (33 mM) +/- BSA or BSAgly (n=6 per group). Isolated hearts were subjected to global or regional ischemia protocols as before (2).  Immunoblotting was performed on stored ventricular tissues for various markers of the ubiquitin-proteasome system (UPS), oxidative stress, inflammation and apoptosis. These data revealed impaired cardiac function with ischemia-reperfusion under acute hyperglycemic conditions together with enhanced myocardial UPS, AGE and inflammatory markers. This is consistent with our previous findings where higher UPS lowered cardiac function together with increased oxidative stress, inflammation and cell death (3).  For the current study, BSA treatment offered cardioprotection by augmenting antioxidant capacity while lowering UPS activation.  However, albumin's cardioprotective effects are lost when modified by glycation and BSAgly hearts displayed activated UPS (in part) together with increased inflammation, loss of antioxidant capacity and higher AGE levels.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
الف براءة اختراع (العلاج لكل شيء)
Creators: name: Abdul Kareem K. Alelaimat, Abdul Kareem
Publisher: name: Alelaimat Chemistry Laboratory
Year: 2025

description: This file is the collection of Thousand patents of the major patent idea of the treatment for all diseases J.A.F. fingal, as the based ideas for it, then the file is regsitered as the organisation of the EU organisations by EU organisation number as the costs of the patents applications registrations and it primary regsitered as the copyrighted file. Attend to that (all of the patents rights regsitered as the company is The Wiser Love and it regsitered legally in erasmos plus, for buying it and dealing with it)
Don Quixote: Freedom of Interpretation Without Boundaries
Creators: name: Payoute, Fabienne
Publisher: name: Georgia State University
Year: 2019

description: The objective of this thesis is to focus on techniques devised by Miguel de Cervantes Saavedra to create several narratives around reality and the imagination. This thesis identifies these narratives, isolates them, and studies their functions within a larger narrative aim: the creation of the first modern novel. Cervantes uses different perspectives within a main plot and several subplots to create a complex narrative. This complexity is achieved by the creation of stories within stories, recounting the adventures of Don Quixote through different authorial voices, sources and times, as well as doppelgangers, pseudonyms, and an alter-ego. All the different narratives give readers, a kaleidoscopic effect in which the observer must make decisions, thus also creating a modern reader.
TAMMAR cruise,Le Nadir R/V
Creators: name: GENTE Pascal
Publisher: name: Sismer
Year: 1996

description: La campagne TAMMAR avec le submersible Nautile avait pour objectif l'exploration d'un segment d'accrétion d'une dorsale lente (la dorsale médio-Atlantique) depuis le centre jusqu'aux extrémités du segment. Des coupes transverses à l'axe ont ainsi été réalisées depuis la partie active vers l'ancienne croûte âgée d'environ 2 million d'années.
Une série de plongées a permis également d'explorer la zone centrale du segment où de grands champs de laves très fluides affleurent.Les principaux résultats de cette campagne concernent le volcanisme, la fracturation, la construction des reliefs sous-marins et la structure magnétique fine de la croûte, un magnétomètre japonais ayant été installé sur le submersible. La particularité du segment exploré est qu'il correspond à un des segments des plus actifs (peut être le plus) en terme de magmatisme de la dorsale Atlantique.
Immunogenicity of biological macromolecules damage by advanced glycation endproducts (AGEs): A Probable Bio-marker for the Auto-immune Diseases
Creators: name: Ahmad, Saheem
name: Akhter, Firoz
name: Khan, M. Salman
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Immunogenicity is the ability of a particular substance, such as an antigen or epitope, to provoke an immune response in the body of a human or an animal. There has been a recent development in the study of the immunologic behaviour of the modified DNA and proteins in the induction and furtherance of immunogenicity [1]. Our Research group has shown that advanced glycation end-products (AGEs) plays a major role in the structural perturbations of DNA, LDL and as well as HSA biological macromolecules [2]. Glucose reacts non-enzymatically with protein amino groups to initiate glycation, the early stage of the Maillard reaction and forms AGEs [3-4]. The AGEs thus formed has several roles in the development of pathological conditions like, diabetes mellitus, arthritis and aging. Recently, the role of carbonyl species modified human placental DNA in the induction of circulating cancer auto-antibodies has also been reported [5]. Therefore, in my opinion the auto-antibodies against the damaged DNA might be used for the early detection of the disease, caused by reactive species.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
iRAGE AS A NOVEL CARBOXYMETHYLATED PEPTIDE THAT PREVENTS AGE-INDUCED APOPTOSIS AND ENDOPLASMIC RETICULUM STRESS IN VASCULAR SMOOTH MUSCLE CELLS
Creators: name: Maltais, Jean-Sébastien
name: Simard, Elie
name: Froehlich, Ulrike
name: Denault, Jean-Bernard
name: Gendron, Louis
name: Grandbois, Michel
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: RAGE overexpression in smooth muscle cells of vulnerable atheromatous plaques suggests a central role in their apoptosis and in diabetes-related cardiovascular events. With the goal of preventing RAGE activation, we synthesized a peptide (iRAGE) whose sequence is derived from an 11-amino acid site surrounding lysine-378, a frequently glycated binding site of carboxymethyllysine-human serum albumin (CML-HSA) in vivo. Pretreatment with iRAGE was successful to prevent RAGE signaling via NF-κB, a major contributor to chronic inflammation. Moreover, as RAGE activation induced apoptosis of more than 75.6% of smooth muscle cells stimulated with CML-HSA, the peptide inhibited RAGE-induced apoptosis and normalized the expression of Bcl-2 homologs, key regulators of the mitochondrial pathway of apoptosis. Interestingly, RAGE blockade diminished the generation of endoplasmic reticular stress, as observed by reduced formation of stress granules and lesser expression of stress marker HuR. This result is of particular interest since HuR can regulate apoptosis by increasing the expression of caspase-9, an event that is prevented by treatment with iRAGE. As activation of RAGE involves the oligomerization of the receptor, our results support the model by which iRAGE inhibits RAGE signaling by hindering the binding of multimeric ligands and by stabilizing the receptors in a monomer state.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Supplementary document for Self-powered p-CuI/n-GaN heterojunction UV photodetector based on thermal evaporated high quality CuI thin film - 5860046.pdf
Creators: name: Zhou, Zhiying
name: Zhao, fengzhou
name: Wang, Cheng
name: Li, Xiaoxuan
name: He, Shunli
name: Tian, Dan
name: Zhang, DengYing
name: Zhang, Lichun
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental images.
Mutilation Génitale Féminine : Le Cas de la Région du Haut Ghana Occidental du Xixe Siècle Au Xxie Siècle
Creators: name: Doku, Juliet
Publisher: name: Georgia State University
Year: 2019

description: Dans plusieurs sociétés du monde, surtout en Afrique, il existe des cultures et pratiques traditionnelles qui suppriment la liberté des femmes. L’une des pratiques dont on parle dans cette étude concerne la mutilation génitale féminine. Ces travaux se centre sur la Région du Haut Ghana occidental dans le but de comprendre les facteurs qui favorisent cette pratique et de proposer des solutions tangibles qui pourraient aider à mettre fin à cette tradition primitive et dangereuse dont les filles et les femmes sont les victimes au cœur de sociétés où cette tradition est toujours pratiquée.
Dietary advanced glycation end-products and chronic kidney disease: Higher consumption of AGEs through dietary fat
Creators: name: Ejtahed, Hanieh-Sadat
name: Angoorani, Pooneh
name: Asghari, Golaleh
name: Mirmiran, Parvin
name: Azizi, Fereidoun
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objectives: Accumulation of advanced glycation end-products (AGEs) are thought to have adverse effects on kidneys through oxidative stress, inflammation and endothelial dysfunction (1). We designed this study to evaluate longitudinal association between dietary AGEs and risk of chronic kidney disease (CKD) in a population based study.
 Methodology: Of 3462 subjects of the third phase of Tehran Lipid and Glucose Study (TLGS), evaluated after approximately 3 years, 1692 participants, free of baseline CKD with complete follow up data, remained for longitudinal analysis. Daily consumption of carboxymethyl lysine (CML), a major type of dietary AGEs, was determined using a validated semi-quantitative food frequency questionnaire (2). CKD was defined as eGFR<60 ml/min/1.73 m2 based on the national kidney foundation guidelines.
Results: Mean dietary intake of energy-adjusted AGEs was 8336±1532 kU/day. Longitudinal analysis indicated that compared to the first quartile category of AGE intakes from fat, in participants of the fourth quartile category, the risk of CKD increased (OR: 2.02, 95% CI: 1.16-3.54). The odds of CKD had increasing trends across increasing categories of AGE intakes (P for trend <0.05).
 Conclusion: Higher consumption of AGEs through dietary fat was associated with higher risk of CKD.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
TASSERGAL - CAP 73-11 cruise,Capricorne R/V
Creators: name: BOELY Thierry
Publisher: name: Sismer
Year: 1973

description: Evaluation des ressources en poissons pélagiques au-dessus du plateau continental de 17°30 à 21° de latitude nord. Identification des échotraces et évaluation du stock de Tassergal. Pèches de contrôle. Couverture planctonologique.
La Representation De La Femme et Les Enfants-Soldats En Periode De Conflit Dans Allah n'est pas oblige d'Ahmadou Kourouma
Creators: name: Afolabi, Daniel
Publisher: name: Georgia State University
Year: 2020

description: Le choix du sujet du present travail a ete dicte premierement par le fait que Allah n'est pas oblige est une representation typique de l'image de la femme et des enfants-soldats en periode de conflits armes en tenant compte de l'espace et du temps: les pays africains ( le Liberia et la Sierra-Leone) post-independance en temps de guerre civile. Evidemment, le roman traite aussi de sujets de l'actualite africaine qui constituent un obstacle considerable au developpement et, a l'epanouissement du peuple africain et largement ce continent. La femme et les enfants-soldats les eternels victimes sont les plusconcernes de ce roman. Cette etude va justifier que la difference identitaire entre l'homme et la femme contribue a creer une difference de traitement et d'experience pendant les conflits armes, car la femme et les enfants payent le plus grand prix pendant ces conflits armes en Afrique et par tout dans le monde.
The effect of advanced glycation end-products consumption on lipid profile
Creators: name: Angoorani, Pooneh
name: Ejtahed, Hanieh Sadat
name: Mirmiran, Parvin
name: Mirzaei, Sahar
name: Azizi, Fereidoun
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objective: To evaluated the association between dietary Advanced glycation end products (AGEs) and risk of hyperlipidemia, in a representative sample of Iranian adults participated in the fourth phase of Tehran Lipid and Glucose Study (TLGS).
Methods: This cross-sectional study was conducted among 5848 men and women, aged 19-70 years. The carboxymethyl lysine (CML) was determined in food items of fourth phase of TLGS food frequency questionnaire (FFQ) by using the American published food CML-AGE database and adjusted for daily energy intake and categorized by using quartile cutoffs. The association between lipid profiles in each quartile category of AGE consumption was estimated using the multivariate logistic regression models.
Results: Mean age of participants (43% men) was 40.6±12.9 years. Mean dietary intake of energy-adjusted AGEs was 8826±3498 kU/day. Daily energy intake of participants was significantly different between the quartile categories of AGEs (P<0.01). Subjects in the highest compared to the lowest quartile category of AGEs had 26% higher risk of hypertriglyceridemia (OR: 1.26 95% CI: 1.07-1.49); but no significant association observed between AGEs consumption and low HDL-C.

Conclusion: Higher intake of AGEs was associated with higher risk of hypertriglyceridemia but has no effect on low HDL-C in Iranian adults
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
TARASOC cruise,Alis R/V
Creators: name: BOUCHET Philippe
Publisher: name: Sismer
Year: 2009

description: Le programme ZEPOLYF (Zone Economique de la Polynésie Française) a découvert en 1996 et cartographié un alignement de seamounts s'étendant sur 700 kilomètres au sud-ouest de Tahiti : la chaine des monts Tarava. Leur âge se situe entre 35 et 50 millions d'années, soit considérablement plus que les îles de la Société actuellement émergées. Plusieurs de ces seamounts ont des plateaux sommitaux situés entre 600 et 900 mètres de profondeur. Cette structure, sans équivalent dans le Pacifique Sud, était jusqu'à maintenant vierge de toute exploration biologique. Les pentes des îles de la Société elles-mêmes restaient méconnues au plan du benthos profond.L'objet de la campagne TARASOC était donc d'explorer la faune benthique des deux chaînes, la chaine sous-marine des Monts Tarava et celle - émergée - des iles de la Société, avec trois objectifs emboités :
1) Description de la faune, caractérisation moléculaire des espèces, et découverte probable d'espèces nouvelles ;
2) Recherche de corrélations entre l'âge et l'isolement des seamounts/îles, d'une part, et la composition de la faune benthique et les stratégies de dispersion des espèces, d'autre part (Endémisme et biogéographie) ;
3) Valorisation de certaines espèces par des études plus ciblées de recherche de molécules bioactives. Les projets de rattachement sont CenSeam et MarBol.La campagne s'est déroulée en deux legs. Le premier leg a ciblé l'exploration de la chaîne des Monts Tarava (11 jours) et ouest de la chaine des Tuamotu (8 jours) ; le second celle des pentes océaniques des Iles de la Société (18 jours). Un total de 213 opérations à la drague et au chalut a été réalisé.
TATU cruise,Coriolis R/V
Creators: name: ROUGERIE Francis
Publisher: name: Sismer
Year: 1985

description: Description des caractéristiques hydrologiques et physico-chimiques des eaux océaniques ayant balayé l'archipel des Tuamotu : 1) Mesure directe du champ des courants entre 0 et 600 mètres ; 2) Evaluation, à proximité des atolls, des perturbations apportées aux caractéristiques hydrologiques des eaux de la dérive ouest (Courant Equatorial Sud) ; 3) Description fine des caractéristiques hydrologiques et physico-chimiques des eaux lagonaires ; 4) Soutien logistique à des programmes connexes (pose de radeaux D.C.P., carottage dans les sédiments, biométrie lagonaire).
Endothelial dysfunction improves with Advanced glycation end-products inhibitor in Rheumatoid Arthritis
Creators: name: Garg, Nidhi
name: Syngle, Ashit
name: Vohra, Kanchan
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objective:
 Increased cardiovascular risk in rheumatoid arthritis (RA) provides a strong rationale for early therapeutical interventions. In view of the similarities between atherosclerosis and RA and the proven benefit of advanced glycation end products (AGEs) inhibitor in atherosclerotic vascular disease,1 the study aimed to delineate the impact of AGEs inhibitor (benfotiamine 50mg+ pyridoxamine 50mg + methylcobalamin 500µg, Vonder) on endothelial dysfunction (ED) in patients with RA.
 Methods:
 24 RA patients received 12 weeks of treatment with oral AGEs inhibitor twice a day as an adjunct to existing stable antirheumatic drugs. ESR, CRP, nitrite, endothelium-dependent and independent vasodilatation of the brachial artery measured at baseline and after treatment.
 Results:
 FMD increased significantly (p<0.01) after treatment whereas there was no significant change in endothelium-independent vasodilation with nitroglycerin and baseline diameter. ESR, CRP and nitrite improved significantly (p<0.05) after treatment. Significant negative correlation was observed between FMD and nitrite at baseline and between FMD and CRP after treatment.
 Conclusion:
 AGEs inhibitor improves inflammation and ED in RA. The vasculoprotective effect of AGEs inhibitor in RA appears to be due to its anti-inflammatory effect.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Les Motivations A Apprendre Pour Les Non-Francophones
Creators: name: Adjei Kankam, Derrick
Publisher: name: Georgia State University
Year: 2020

description: Nous estimons qu’à GSU les apprenants ont des motivations individuelles pour étudier le français car ils étudient normalement le français pendant un semestre ou deux et continuent rarement à suivre des cours au niveau avancés. Cette situation est le contraire d’objectif du département de WLC qui cherche à retenir le plus d’apprenants possible dans le programme de français. Nous jugeons donc nécessaire d'étudier en détail la motivation des apprenants à suivre des cours de français au niveau élémentaire et intermédiaire afin de concevoir un enseignement et un apprentissage répondant aux objectifs des apprenants.
"Prevention of glycosylation by natural and synthetic antioxidants"
Creators: name: Sadowska-Bartosz, Izabela
name: Galiniak, Sabina
name: Stefaniuk, Ireneusz
name: Bartosz, Grzegorz
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: One of the main mechanisms of etiopathogenesis of diabetes and diabetic complications is an increase in the level of glycation of proteins due to increased concentrations of glucose and other reactive metabolites. The level of protein glycation is elevated also in other diseases such as multiple sclerosis or cystic fibrosis [1]. The search for new compounds protecting against glycation is thus of paramount importance. Our studies confirmed the high efficiency of natural polyphenols in this respect and identified, for the first time, a new class of compounds, stable free nitroxyl radicals that can counteract glycation. The effectiveness of nitroxides in the prevention of glycation correlates with their reactivity with non-oxygen centered radicals. SAR analysis should allow for the design and synthesis of more effective nitroxides [2]. 1-Cyano-4-hydroxycinnamic acid is an effective inhibitor of protein glycation in vitro [3]. This compound may not be directly applicable in vivo due to its other biological effects (inhibition of transport of carboxylic acids) but can be a starting point for the synthesis of new derivatives. Analysis of the relationship between the structure and antiglycating activity of nitroxides should allow for the design of new medicines with maximal efficiency and minimal side-effects.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Information Infrastructures in the Era of AI: Opportunities and Challenges. E-Science-Tage workshop
Creators: name: Jacyszyn, Anna M.
name: Sack, Harald
name: Bach, Felix
name: Singson, Lea Sophie
name: Bonatto Minella, Christian
name: Zimmermann, Hannah
name: Jung, Nicole
name: Becker, Silvia
name: Loewe, Axel
name: Kerzenmacher, Tobias
name: Nierling, Linda
name: Dähms, Angelina Sophie
name: Silaban, Ely Nova Natalia
Publisher: name: Zenodo
Year: 2025
Subjects: digital transformation
digitalisation

description: This is a presentation of the workshop "Information Infrastructures in the Era of AI: Opportunities and Challenges" organised by the DiTraRe team which took place on the 12th of March 2025 during the E-Science-Tage in Heidelberg.
TAT 9 cruise,Jean Charcot R/V
Creators: name: Jean-François, BOURILLET
Publisher: name: Sismer
Year: 1988

description: Reconnaissance bathymétrique de la partie profonde (inférieure à 500m) de la trace pour le câble optique (Transatlantique Telecom 9e) entre New-York et Cadix. Prestation pour un Consortium de 5 organismes : France Telecom, British Telecom International, Telefonica de Espana SA, Teleglobe Canada Inc, A.T.&T.(USA). Contrat IFREMER no 88/1210789/BF.
AGE accumulation contributes to synaptic dysfunction
Creators: name: Yan, Shirley ShiDu
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Advanced glycation endproducts (AGEs) are members of a heterogeneous class of molecules. AGEs accumulate with aging, diabetes, and neurodegenerative diseases. Excess AGE accumulation is progressive factor accelerating and exacerbating neuronal dysfunction, contributing to cognitive decline in normal aging and age-related neurodegenerative diseases including Alzheimer’s disease. Synaptic dysfunction is an early pathological feature associated with aging and neurodegeneration. Whether and how AGEs are involved in alterations in synaptic structure and function are not well understood. We have demonstrated that application of AGEs to brain slices impaired hippocampal long term potentiation (LTP), a maker for synaptic function and transmission. The treatment of AGEs causes loss of synapses as shown by significant reduction in synaptic density. Deficiency of neuronal RAGE or dominant-negative RAGE (DN-RAGE) rescues synaptic function and structure. RAGE-deficiency or DN-RAGE blocks AGE-induced activation of p38 signaling. RAGE deficiency also affords a protective effect on diabetes-induced synaptic dysfunction and impairment in learning and memory. These results suggest that AGEs contribute importantly to synaptic and cognitive dysfunction associated with neurodegeneration in aging and diabetes.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Oxidative Stress Mediated Cytotoxicity of Glycated Albumin: Comparative Analysis of Glycation by Glucose Metabolites
Creators: name: Khan, Mohd Shahnawaz
name: Al-Senaidy, Abdulrehman M
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The non-enzymatic reaction between reducing sugars and proteins has received increased attention in nutritional and medical research recently. In the current manuscript, effect of glycation in structural changes of human serum albumin (HSA) by the metabolites of glucose such as glyoxal, methylglyoxal and glyceraldehyde was studied using different spectroscopy techniques. Glycation of HSA was monitored by following advanced glycation end-products (AGEs) fluorescence changes, HSA intrinsic fluorescence measurement, extrinsic fluorescence using 8-analino 1- nephthlene sulfonic acid (ANS) dye, and circular dichroism (CD) studies. AGEs were formed within 7 days of incubation with glyoxal, methylglyoxal and glyceraldehyde. However, methylglyoxal induced significant structural changes in HSA compared with glyoxal and glyceraldehydes. Moreover, ANS binding to native and glycated-HSA showed difference in binding pattern of these metabolites to HSA. The CD spectrum revealed changes in the secondary structure of HSA upon glycation when compared to native HSA. Furthermore, the MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide) assay established the cytotoxicity of the glycatedHSA towards human liver carcinoma (HepG2) cell lines via the production of reactive oxygen species.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Glycated apolipoprotein A-I exacerbates cellular senescence in human umbilical vein endothelial cells accompanied by impaired insulin secretion activity and embryo toxicity
Creators: name: Park, Ki-Hoon
name: Kim, Jae-Yong
name: Cho, Kyung-Hyun
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Glycation of apolipoproteins is a major feature of production of dysfunctional high-density lipoproteins (HDL), which is associated with incidence of several metabolic diseases such as coronary artery disease and diabetes.  High-density lipoprotein (HDL) and apolipoprotein (apo) A-I have strong antioxidant and anti-inflammatory properties in the plasma.   Fructose-induced non-enzymatic glycation of apoA-I can lead to the production of dysfunctional apoA-I and HDL.  To compare the physiologic effects of dysfunctional apoA-I and HDL, reconstituted HDL containing native apoA-I (nA-I) or glycated apoA-I (gA-I) was injected into zebrafish embryos in the presence of inflammatory molecules. Co-injection of oxidized LDL (oxLDL) and nA-I-rHDL improved embryo survival, while co-injection of oxLDL and gA-I-rHDL aggravated inflammatory deaths.  Using pancreatic β-cells, insulin secretion was impaired by gA-I in the lipid-free and reconstituted HDL (rHDL) states up to 35%, and 40%, respectively, under hyperglycemic conditions (25 mM glucose). Treatment with gA-I and HDL from elderly patients to human umbilical vein endothelial cells (HUVECs) caused 1.8-fold, and 1.5-fold increased cellular senescence, respectively, along with increased lysosomal enlargement. In the lipid-free and rHDL states, gA-I caused 1.5-fold and 2.5-fold higher embryo death, respectively, along with production of oxidized species. Furthermore, rHDL containing gA-I (gA-I-rHDL) showed a higher isoelectric point (pI, approximately 8.5), whereas rHDL-containing nA-I (nA-I-rHDL) showed a narrow band range with lower pI (around 8.0) as well as much smaller particle size than that of nA-I-rHDL.Conclusively, fructose-mediated apoA-I glycation resulted in severe loss of several beneficial functions of apoA-I and HDL, including anti-senescence and insulin secretion activities, accompanied by increased susceptibility of protein degradation and structural modification.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
High-density lipoprotein oxidation in type 2 diabetic patients: is it a glycation-catalyzed process?
Creators: name: Lapolla, Annunziata
name: Seraglia, Roberta
name: Roverso, Marco
name: Sartore, Giovanni
name: Burlina, Silvia
name: Bolis, Angiola
name: Marina, Raffaella
name: Manzato, Enzo
name: Ragazzi, Eugenio
name: Traldi, Pietro
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Among long-term diabetic complications, cardiovascular disease is one of the major causes of premature death. High density lipoproteins (HDL) play an important role in the control of vascular damage but ApoA-I can undergo oxidative changes that reduce their antiatherogenic role. The aim of this study was to evaluate methionine sulfoxide (MetO) content in the ApoA-I of HDL isolated from type 2 diabetics and healthy subjects. We evaluated the lipid profile of 21 type 2 diabetic patients and 21 healthy volunteers and determined in all subjects the MeO content in ApoA-I by MALDI/TOF/TOF technique. The typical MALDI spectra of the tryptic digest obtained from HDL plasma fractions from all patients showed a relatively increased abundance of peptides containing Met112O in ApoA-I from type 2 diabetic patients. Interestly  a strong correlation emerged between the duration of the diabetes and MetO levels in ApoA-I. However no correlation was found between MetO levels in ApoA-I and HbA1c, indicating that ApoA-I oxidation appears unrelated to the degree of glycemic control. MetO levels in ApoA-I, measured using an accurate and specific method, should be investigated in order to assess their possible role as a novel risk factor to reduce the burden of cardiovascular complications.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Electrocatalytic Assay for Monitoring Methylglyoxal-mediated Protein Glycation
Creators: name: Svrčková, Marika
name: Zatloukalová, Martina
name: Ulrichová, Jitka
name: Novák, David
name: Vacek, Jan
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Protein glycation has been implicated in various disease states and is therefore an important process in aging and age-related chronic diseases. At the molecular level, protein glycation has important implications for protein activity, unfolding and degradation.
 We here introduce a novel sensing strategy for protein glycation based on electroactivity measurement. Concretely, the label-free method proposed is based on the application of a constant-current chronopotentiometric stripping analysis at Hg-containing electrodes (Havlíková et al. 2015).

 Two model proteins were used: serum protein albumin (bovine and human) and membrane protein Na+/K+-ATPase. Results were investigated over 4–72 hours of incubation with the glycation agent methylglyoxal in the absence or presence of the glycation inhibitor aminoguanidine. We compared the results acquired by electrocatalytic assay with the results of complementary methods frequently used for glycation analysis, including specific protein activity measurement.
 Based on our results, we can say that our approach primarily reflects changes in ‘protein surface chemistry’ in comparison to other methodologies. In addition to this, the approach proposed here could be the starting point for the further development of novel techniques for protein glycation detection, especially electrochemical sensors and versatile sensing platforms.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
Etude Sur le Roman D'apprentissage Français du Xixème
Creators: name: Payoute, Fabienne
Publisher: name: Georgia State University
Year: 2020

description: L’objectif de ce mémoire est de se focaliser sur les romans d’apprentissage français du XIXème siècle, pour cela nous allons comparer trois differents romans dont Le Père Goriot écrit par Honoré Balzac, L’Éducation Sentimentale de Gustave Flaubert ainsi que Le Rouge et le Noir de Stendhal. Dans un premier temps, nous nous focaliserons sur l’apprentissage de la vie d’adulte faite par nos trois jeunes protagonistes. Ces trois romans décrivent les idéaux et les ambitions qui représentent les aspirations de toute leur génération. Nous analyserons aussi les autres personnages, la dualité province-capitale et quelques divers événements historiques venant s’ajouter aux décors qui ont pour but de créer des œuvres sociologiques car la société dans laquelle ils ont évolués les a transformés.
TEC-SEDHETE cruise,Thalia R/V
Creators: name: BLANPAIN Olivier
Publisher: name: Sismer
Year: 2007

description: Essais technologiques d'une structure instrumentée qui permet de filmer une coupe du sédiment dans le but de caractériser la dynamique sédimentaire sur des fonds fortement hétérogènes.Le projet de rattachement est MODECOGEN.
Creation of Matter and Atoms in Pure Time Theory - A First-Principles Derivation
Creators: name: Allou, Essam
Publisher: name: Zenodo
Year: 2025
Subjects: Pure Time Theory
PTT
Matter Creation
Temporal Field
Quantum Genesis
Spontaneous Matter Formation
Emergent Space-Time
Time Relaxation Field
Cosmology
Fundamental Physics
Astrophysics
Dark Matter Alternative
Quantum Vacuum
Energy-Matter Coupling
Cosmic Structure Formation
Non-Static Universe

description: This paper establishes a unified theoretical framework for matter creation and cosmic evolution within Pure Time Theory (PTT), where spacetime and matter emerge from gradients of a primordial temporal field T (xμ). By quantizing T (xμ) and coupling it to emergent quantum fields, we derive:

Particle production rates via Bogoliubov transformations (ni ∝ β3/2T −3relax),

Mass generation through temporal rigidity (mp ≈ 938 MeV for β = 1.203),

Testable spectral signatures in atomic transitions (∆λ/λ ∝ ∇Trelax).

Cosmological simulations predict a 7%±2% enhancement in the matter power spectrumat k > 0.05 h Mpc−1, consistent with mock SDSS-like data.

While these results align with PTT’s axioms, eliminating dark matter and dark energy, they await empirical validation.

This work transitions PTT from mathematical speculation to a falsifiable paradigm, with definitive tests proposed via Casimir force deviations (0.14%), white dwarf soft X-ray excess (0.12 eV), and redshift-dependent fine-structure variations (∆α/α ∼ 10−6).
Le Mariage Précoce en République de Guinée
Creators: name: Ba, Mariama
Publisher: name: Georgia State University
Year: 2020

description: Dans tous les continents du monde entier, les sociétés disposent de différentes cultures et traditions, de comportements et de pratiques auxquels chaque communauté s’adapte, croit et pratique quotidiennement. Ces comportements et croyances sont plus souvent au détriment des droits de la femme. Dans cette étude, nous parlerons d’une des pratiques très fréquentes en Afrique de l’Ouest, plus précisément en Guinée, qui est le mariage précoce. Cette enquête s’étend sur tout le territoire guinéen dans le but de faire une analyse générale des causes profondes de ce phénomène illégal, en vue de trouver et de présenter des solutions concrètes afin d’éradiquer progressivement ces pratiques négatives voire fatales faites à l’égard de la jeune fille et de la femme.
TEAHITIA 4 cruise,Le Suroît R/V
Creators: name: AVEDIK Felix
Publisher: name: Sismer
Year: 1989

description: Cette campagne avait pour objectif l'étude, par la sismique multitrace, de la structure de l'édifice volcanique des iles de la Société (Polynésie Française). L'étude se concentre plus particulièrement sur les volcans actuellement actifs de l'édifice, tels que les volcans 'Mehetia' et 'Rocard', à proximité de Tahiti, dans le but de mieux connaitre le processus de mise en place de magma dans la croute océanique, l'un des mécanismes importants de son accrétion. Une meilleure connaissance de ce processus pourrait également fournir les éléments pour l'appréciation des risques volcano-sismiques liés.
OʻZBEK MAROSIM QO'SHIQLARI: SHAKLLANISHI, FUNKSIYASI VA BUGUNGI KUNDAGI AHAMIYATI
Creators: name: Raximova, Aziza
name: Muxammedova, Zumrad
Publisher: name: Zenodo
Year: 2025

description: Mazkur maqolada o‘zbek xalqining boy og‘zaki an’anaviy ijodi doirasida shakllangan marosim qo‘shiqlarining tarixiy ildizlari, shakllanish bosqichlari, turlari hamda ularning ijtimoiy-madaniy funksiyalari ilmiy asosda yoritilgan. O‘zbek xalqining to‘y, hosil yig‘imi kabi turmush marosimlari doirasida ijro etilgan qo‘shiqlar misolida ularning xalq hayotidagi axloqiy, estetik va pedagogik ahamiyati tahlil qilinadi. Shuningdek, zamonaviy jamiyatda marosim qo‘shiqlarining saqlanib qolishi, ularning folklor ansambllar, maktab va OTMlarda o‘quv-tarbiyaviy vosita sifatidagi o‘rni hamda madaniy meros sifatida yosh avlodga yetkazilish muammolari ham ko‘rib chiqiladi.
First Steps Towards AI Integration of the Tromsø Repository of Language and Linguistics (TROLLing)
Creators: name: Conzett, Philipp
Publisher: name: Zenodo
Year: 2023
Subjects: subject: research data
subject: FAIR data
subject: Artificial intelligence
subject: Dataverse
subject: TROLing
subject: repositories

description: Presentation given at CLARIN and Libraries 2023: Large Language Models and Libraries, The National Library of Norway, December 6, 2023
Endothelial cell dysfunction caused by diabetes and age related reactive dicarbonyls
Creators: name: Simm, Andreas
name: Jacobs, Kathleen
name: Navarrete-Santos, Alexander
name: Treede, Hendrik
name: Hofmann, Britt
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Background  Advanced Glycation Endproducts (AGEs) as well as AGE inducing dicarbonyls are involved in cardiovascular aging. Circulating dicarbonyls like Glyoxal (GO) and Methylglyoxal (MGO) are directly in contact with endothelial cells (ECs) and may be able to modulate EC function.
 Methods
 Primary culture ECs were isolated from bypass graft material (HSVECs, human saphenous vein endothelial cells) of patients. HSVECs were chronically stimulated with low and high in vivo glycated BSA, GO and MGO and analyzed according to cell senescence and function.
 Results
 Our results show that GO leads to cell senescence associated changes whereas MGO has no effect. In combination, both dicarbonlys induced senescence-associated β-galactosidase activity and increased p21 protein expression, decreased mRNA expression of cell-adhesion molecules and affect the expression of different receptors for AGEs. In addition, the permeability of HSVEC monolayer decreased after chronic treatment with GO/MGO or with high in vivo-modified BSA.
 Conclusion
 Our findings suggest that elevated levels of diabetes / age related dicarbonyls and AGEs can damage the endothelium by inducing cell senescence and thus promote the development of vascular dysfunction.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
De Machos a Homosexuales. La Transición del Protagonista Masculino entre el Boom y el Post Boom
Creators: name: Luna, Luis
Publisher: name: Georgia State University
Year: 2020

description: En el presente trabajo analizo el cambio en las figuras masculinas a través de los periodos del Boom y el Post Boom. En el trabajo se analizan 3 novelas del periodo del Boom: La muerte de Artemio Cruz, La ciudad y los perros y La traición de Rita Hayworth. Del Post Boom se analizan 2 novelas: Arturo, la Estrella más brillante y El beso de la mujer araña. A través del análisis se brinda evidencia de cómo se representan las figuras masculinas en algunas novelas del Boom. Sin embargo, durante el periodo del Post Boom, algunos autores utilizan figuras homosexuales como los protagonistas de sus novelas.
Relation between welding fumes exposure and plasma advanced glycation end-products among shipyard workers
Creators: name: Lai, Ching-Huang
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Background
Shipyard workers were exposed to high levels of particulate matters contained metals in welding process. Previous study shows chronic exposure to TiO2 nanoparticles resulted in atherogenesis coupling with pulmonary inflammation, advanced glycation end products, reactive oxygen species.
Objective
We assessed quantitatively the relationship between urinary metals and plasma AGEs in shipyard workers.
Methods
The study population, including 74 male shipyard workers and a reference group of 28 administrative workers in the northern Taiwan. We used personal samplers to collect 24 hours PM2.5 exposure samples. The study subjects underwent an interview and a health examination on the next day morning, where blood and urine samples were collected. Urinary metals were analyzed by inductively coupled plasma mass spectrometry. Plasma AGEs levels were determined using commercial ELISA kits.
Results
Using multiple linear regression analysis adjusting for age, smoking status, alcohol intake habit, family history of diabetes mellitus, a change in log(AGEs) were statistically significantly related to a unit change in log(cobalt) ( β= 0.12, 95% CI 0.01 to 0.26) and in log(lead) (β= 0.10, 95% CI 0.04 to 0.25), respectively.
Conclusion

Welding workers in shipyard exposed to high levels of particulate matters contained metals could increase AGEs formation in the body.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
L'étude de L'utilisation du Créole dans les Familles Haïtiennes Vivant dans la Partie Centrale Nord de L'état de Géorgie
Creators: name: Montreuil, Carline
Publisher: name: Georgia State University
Year: 2020

description: Les questions de cette enquête concernent l'utilisation du Créole et l'immersion de la culture haïtienne dans les foyers. Les participants de cette étude sont des parents Haïtiens, principalement situés dans la région du centre-nord de la Géorgie. Les méthodes et procédures distinctes de ce projet sont des méthodes de recherche mixtes, qualitative et quantitative. Les approches de ces formes de données exploitées, permettront une compréhension plus complète du problème de la recherche. Certaines questions seront ouvertes et d’autres nécessiteront des réponses semblables à celles d’un sondage qui exigent un oui ou un non; un système de classement, du moins probable au plus probable. Un suivi plus complèt aurait fait auprès des enfants des répondants; cependant, en raison des contraintes de COVID-19, cela s'est avéré impossible. Néanmoins, les résultats de cette investigation analysent efficacement dans quelle mesure les immigrants Haïtiens-Américains ne choississent pas à utiliser la langue Créole dans leurs familles.
Supplementary Material.pdf
Creators: name: Saha, Gourab
name: PODDAR, NANDA
name: MONDAL, KAJAL KUMAR
name: Wang, Ping
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 490199
subject: Applied mathematics not elsewhere classified
classificationCode: 401299
subject: Fluid mechanics and thermal engineering not elsewhere classified

description: The supplementary file of the study entitled "Evolution of concentration distribution and removal of a solute in MHD Channel Flow: effects of buoyancy-driven force and induced magnetic field."
Glycation of plant proteins during environmental stress and ageing: methodological approaches, potential mechanisms and biological role
Creators: name: Frolov, Andrej
name: Bilova, Tatiana
name: Greifenhagen, Uta
name: Paudel, Gagan
name: Lukasheva, Elena
name: Tarakhovskaya, Elena
name: Frolova, Nadezhda
name: Mittasch, Juliane
name: Brauch, Dominic
name: Osmolovskaya, Natalia
name: Balcke, Gerd Ulrich
name: Tissier, Alain
name: Vogt, Thomas
name: Milkowski, Carsten
name: Birkemeyer, Claudia
name: Wessjohann, Ludger
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Environmental stress is the major factor reducing crop productivity. The alterations in temperature, salinity, light and water regimen result in overproduction of reactive oxygen species and sugar metabolites. The combination of these factors enhances protein glycation. Resulting advanced glycation end-products (AGEs) are known to be pro-inflammatory in mammals. Recently, their presence was unambiguously demonstrated in vivo in stressed Arabidopsis thaliana plants [1]. However the protein targets, mechanisms and agents of glycation in plants are still unknown. Therefore, here we comprehensively characterize plant glycated proteome, as well as its time- and stress-related alterations, by the methods of bottom-up LC-based in-depth proteomics, and enclose the underlying mechanisms of AGE formation [2]. Using in vitro peptide-based glycation models, reactivity and glycation potential of individual plant sugars were addressed and considered in the context of in vivo abundances of corresponding metabolites. Thus, approximately 800 individual AGE-modified proteins were annotated. Thereby, monosaccharide autoxidation was the major pathway of their formation, whereas dihydroxyacetone phosphate, glyceraldehyde-3-phosphate, ribulose, erythrose, and sucrose were the most probable plant AGE precursors. The rates of glycation were increased under stress conditions and during life span.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 2 (2016): Journal of ISANH Volume 3: Special Issue for Maillard Reaction & Glycation
TECHAUV cruise,L'Europe R/V
Creators: name: Stéphan, KER
name: PACAULT Anne
Publisher: name: Sismer
Year: 2009

description: Le principal équipement mis en oeuvre au cours de la campagne TECHAUV était l'AUV IDEFx avec comme charge utile le sondeur de sédiments (SDS). Les objectifs de la campagne étaient les suivants : Enregistrement du signal acoustique émis par le transducteur d'émission du SDS avec un hydrophone placé sous le transducteur d'émission. Validation de la nouvelle version du logiciel d'acquisition du SDS (SUBOP V2 installé et testé à terre semaine 18) et des modifications apportées à MIMOSA et au VCC pour prendre en compte le passage à SUBOP V2. Test en endurance du SDS pour valider les modifications apportées à l'électronique en février 2009. Le projet de rattachement est le projet IFREMER "AUV Côtiers' PJ3208.