cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CBS News Poll: 2016 Presidential Election/Trump/The News Media
Creators: name: CBS News
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: President Barack Obama job performance (4); 2016 presidential election (1); national economy (2); opinion of Donald Trump (5); Republican Party united or divided (1); Democratic Party united or divided (1); opinion of Hillary Clinton (1); election of Donald Trump as president (10); confidence in Trump's ability to make the right decisions (5); news media coverage on presidential candidates (2); Cabinet selections (1); Trump's personal Twitter account (1); Trump to publicly release his tax returns (1); Trump’s business relationships (2); voter fraud in U.S. elections (2); the Electoral College (2); popular vote in the 2016 presidential election (1); U.S. trade with other countries (1); tax breaks to corporations (1); 2010 Affordable Care Act (2); 2010 health care law (2); global warming (1); confidence in the news media (1); registered to vote (1); vote in the 2016 presidential election (1); personal finances (1); political party preference (2).
Saquinavir Loaded Acetalated Dextran Microconfetti – a Long Acting Protease Inhibitor Injectable
Creators: name: Ainslie, Kristy M.
name: Kashuba, Angela
name: Sykes, Craig D.
name: Bachelder, Eric M.
name: Gallovic, Matthew D.
name: Collier, Michael A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Since the adoption of highly active antiretroviral therapy, HIV disease progression has slowed across the world; however, patients are often required to take multiple medications daily of poorly bioavailable drugs via the oral route, leading to gastrointestinal irritation. Recently, long acting antiretroviral injectables that deliver drug for months at a time have moved into late phase clinical trials. Unfortunately, these solid phase crystal formulations have inherent drawbacks in potential dose dumping and a greater likelihood for burst release of drug compared to polymeric formulations.
Shocks in the Early Universe
Creators: name: Pen, Ue-Li
name: Turok, Neil
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We point out a surprising consequence of the usually assumed initial conditions for cosmological perturbations. Namely, a spectrum of Gaussian, linear, adiabatic, scalar, growing mode perturbations not only creates acoustic oscillations of the kind observed on very large scales today, it also leads to the production of shocks in the radiation fluid of the very early universe. Shocks cause departures from local thermal equilibrium as well as creating vorticity and gravitational waves. For a scale-invariant spectrum and standard model physics, shocks form for temperatures $1$ GeV$
description: 5 pages, 3 figures, accepted for publication in Physical Review Letters
Dam Removal Science Database Citations
Creators: name: Wieferich, Daniel J
Publisher: name: U.S. Geological Survey
Year: 2016

description: This ScienceBase Item is a collection that contains the citation references used as a basis for the meta analysis in the Dam Removal Science Database. It started as the list of citations used in the Powell Center synthesis project and receives new citations discovered in ongoing algorithm-assisted mining of literature. Citations in the collection include items already in ScienceBase from other sources (e.g., USGS Publications Warehouse) as well as new citations that first originated with the Dam Removal Science Database development.
The asymptotic behavior of the monodromy representations of the associated families of compact CMC surfaces
Creators: name: Heller, Sebastian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A10, 53C42, 53C43

description: Constant mean curvature (CMC) surfaces in space forms can be described by their associated $\mathbb C^*$-family of flat $SL(2,\mathbb C)$-connections $\nabla^λ$. In this paper we consider the asymptotic behavior (for $λ\to0$) of the gauge equivalence classes of $\nabla^λ$ for compact CMC surfaces of genus $g\geq2.$ We prove (under the assumption of simple umbilics) that the asymptotic behavior of the traces of the monodromy representation of $\nabla^λ$ determines the conformal type as well as the Hopf differential locally in the Teichmüller space.
description: 6 pages
Clinical Pharmacology Studies in Critically Ill Children
Creators: name: Gonzalez, Daniel
name: Hornik, Christoph P.
name: Salerno, Sara
name: Thakkar, Nilay
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Developmental and physiological changes in children contribute to variation in drug disposition with age. Additionally, critically ill children suffer from various life-threatening conditions that can lead to pathophysiological alterations that further affect pharmacokinetics (PK). Some factors that can alter PK in this patient population include variability in tissue distribution caused by protein binding changes and fluid shifts, altered drug elimination due to organ dysfunction, and use of medical interventions that can affect drug disposition (e.g., extracorporeal membrane oxygenation and continuous renal replacement therapy). Performing clinical studies in critically ill children is challenging because there is large inter-subject variability in the severity and time course of organ dysfunction; some critical illnesses are rare, which can affect subject enrollment; and critically ill children usually have multiple organ failure, necessitating careful selection of a study design. As a result, drug dosing in critically ill children is often based on extrapolations from adults or non-critically ill children. Dedicated clinical studies in critically ill children are urgently needed to identify optimal dosing of drugs in this population. This review will summarize the effect of critical illness on pediatric PK, the challenges associated with performing studies in this vulnerable subpopulation, and the clinical PK studies performed to date for commonly used drugs.
USGS National Dam Removal Science Database Dam Removals
Creators: name: Wieferich, Daniel J
Publisher: name: U.S. Geological Survey
Year: 2016

description: This ScienceBase Item provides documentation and access to a dynamic query of the Spatial Feature Registry for dam removals that have been associated with a literature source describing the dam removal project and associated scientific studies. The Spatial Feature Registry is a dynamic collection in ScienceBase of geospatial features of importance as long-term, persistently identified items. Dam removal items in the Spatial Feature Registry provide part of the foundation for the National Dam Removal Science Database, a distributed data system with information on the science of dam removal and the basis for the Dam Removal Information Portal. Dam removals in this collection have been quality controlled to the hydrographic network, primarily with the NHD Plus V2, and include identifiers and other attributes that contribute to their utility.
Optimierte Erfassung und Veröffentlichung von Artikelmetadaten für eine nachhaltige Metadatenallmende im OA-Ökosystem zur Unterstützung von Auffindbarkeit und Evaluation
Creators: name: Nüst, Daniel
name: Hauschke, Christian
name: Cordts, Anette
name: Yücel, Gazi
Publisher: name: Zenodo
Year: 2023
Subjects: Open Science
Open Access
Metadatenallmende
Geometadaten
KOMET
OPTIMETA

description: Die Metadatenallmende ist ein wichtiger Baustein für den Wandel hin zu einem diversen Open-Access-Ökosystem. Nur mit offenen und hochwertigen Metadaten, die mindestens die gleiche oder sogar höhere Qualität und Abdeckung als die Metadaten-Silos etablierter kommerzieller Verlage erreichen, können unabhängige Zeitschriften auf Augenhöhe Themen wie Auffindbarkeit und faire Evaluation von Forschenden angehen. Wir stellen einen Arbeitsablauf und Werkzeuge vor, die eine Professionalisierung der Metadatenprozesse von unabhängigen, scholar-led OA-Journals unterstützen. Diese Journals können damit ihre Sichtbarkeit im Wissenschaftssystem und ihre Bedeutung als Publikationsort erhöhen. Dazu wird die global verbreitete Free and Open Source Software (FOSS) Open Journal Systems (OJS) um Funktionen erweitert, die a) Eingabe, Kuratierung und Anreicherung von artikelbezogenen Metadaten durch Autor:innen und Editor:innen und b) den Export dieser Metadaten an offene Datenquellen wie z. B. Wikidata ermöglichen. Diese Erweiterung wird durch OJS-Plugins und auch Anpassung der OJS-Kernsoftware in den folgenden Anwendungsfällen umgesetzt: Erstens ermöglicht die Integration von validierten persistenten Identifikatoren (PIDs) und geographischen Metadaten als Teil der Publikationsmetadaten eine bessere Auffindbarkeit und von Artikeln aus Open-Access-Zeitschriften. PIDs und Geometadaten stellen Verbindungen zu anderen Publikationen, akademischen Events, physischen Proben und wissenschaftlichen Instrumenten her und verknüpfen so verwandte Artikel über Zeitschriften und Wissenschaftsdisziplinen hinweg. Auf Basis dieser Metadaten werden zum Beispiel eine Suchplattform realisiert, die wissenschaftliche Artikel über Disziplingrenzen und Publikationsplatformen hinweg als offene Daten interaktiv auf einer Karte darstellt, und semantisch bedeutsame Links in Artikeln und ihren Landing Pages eingefügt. Zweitens werden Zitationsmetadaten während des Einreichungs- und Begutachtungsprozesses strukturiert erfasst und frei in standardisierten Formaten veröffentlicht. Durch die innovative und benutzerfreundliche Metadatenerfassung im Zuge des wissenschaftlichen Ver­öffentlichungsprozesses können Open-Access-Artikel in transparenten zitationsbasierten Evaluationsmetriken verwendet werden. Diese Neuerungen unterstützen eine offene Publikationskultur und -praxis. In diesem Beitrag berichten wir vom aktuellen Arbeitsstand zu den Anwendungsfällen und beschreiben eine Vision für eine neuartige verteilte Erfassung und Veröffentlichung offener Metadaten.
Dynamic Changes of Peripheral NK Cells Predict Outcome in Patients with PD-L1 Positive Non-small-cell Lung Cancer Undergoing Immune Checkpoint Inhibitors as Second-line Therapy
Creators: name: Nelli, Fabrizio
name: Panichi, Valentina
name: Fabbri, Agnese
name: Natoni, Federica
name: Giannarelli, Diana
name: Topini, Giuseppe
name: Virtuoso, Antonella
name: Berrios, Julio Rodrigo Giron
name: Marrucci, Eleonora
name: Pessina, Gloria
name: Silvestri, Maria Assunta
name: Ruggeri, Enzo Maria
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: We evaluated immune cell frequencies in peripheral blood samples of 41 NSCLC patients before and after second-line therapy with anti-PD-1/PD-L1 agents. Changes in lymphocyte subsets and their correlation with clinical response, progression-free survival (PFS), and overall survival (OS) were analyzed. We observed an increase in median values of all lymphocyte subsets, being significant only for NK cells. A correlation was retrieved between higher post-treatment NK cell level and clinical benefit. On multivariate analysis, PD-L1 tumor proportion score ≥1% and higher post-treatment NK cell counts were predictive of longer PFS and OS. Co-presence of these factors was characterized by longer survival.
Accuracy of the ‘CUT’ Score for Assessing Malignancy in Bethesda 3 and 4 Thyroid Nodules in North American Population: A Retrospective Study
Creators: name: Shihabi, Areej N.
name: Hussein, Mohammad
name: Toraih, Eman A.
name: Attia, Abdallah S.
name: Youssef, Mohanad R.
name: Elnahla, Ahmed
name: Omar, Mahmoud
name: Shama, Mohamed
name: Corsetti, Ralph
name: Kandil, Emad
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Hematology

description: The CUT score is a thyroid nodule malignancy risk assessment scoring system intended to guide surgeons in treating Bethesda 3 and 4 thyroid nodules. It is based on clinical (C) and ultrasonographic (U) features and a five-tiered (T) representing cytology. Our study aimed to assess the utility of the CUT score in predicting thyroid malignancy in the North American population. The main reason for creating this score is to reduce unnecessary surgeries on these challenging thyroid nodules. A retrospective record review study applied the CUT score to 219 Bethesda 3 and 4 thyroid nodules. A total of 203 Bethesda 3 and 16 Bethesda 4 nodules from patients treated between January 2015 and December 2019 at a single institution were assessed. A receiver operating characteristic (ROC) curve analysis was performed to evaluate the CUT diagnostic test. Binary logistic regression analysis was performed. Iteration of analysis was performed after stratification according to body mass index to assess CUT score accuracy in obese and non-obese patients. Of 219 nodules analyzed, 148 were characterized as benign and 71 as malignant. Prevalence rates of malignancy were 29.6% (n = 60) and 68.8% (n = 11) in Bethesda 3 and 4 nodules, respectively. The mean CU (clinical, ultrasonography) score was 5.35 ± 1.38 in benign nodules versus 4.96 ± 1.5 in malignant nodules (p = 0.08). The area under the curve (AUC = 0.433) for the association of CUT scores with nodule malignancy was not significant (p = 0.13). The CUT score was insignificant as a diagnostic test for nodule malignancy in obese (AUC = 0.45; p = 0.72) and non-obese patients (AUC = 0.39; p = 0.08). The CUT score did not correlate with preoperative malignancy risk estimates in Bethesda 3 thyroid nodules and, therefore, may have limited utility as a predictor of malignancy in these thyroid nodules.
Comparison of diagnostic evaluations for cough among initiators of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: Diagnostic Workup in Antihypertensive Drug Initiators
Creators: name: Pate, Virginia
name: Gokhale, Mugdha
name: Stürmer, Til
name: Girman, Cynthia
name: Chen, Yong
name: Funk, Michele Jonsson
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Differential diagnostic evaluation associated with a drug may bias effect estimates due to an increased detection of preclinical outcomes. Persistent cough is a common side effect with angiotensin-converting enzyme inhibitors (ACEI) and we hypothesized that ACEI initiators would undergo more diagnostic evaluations, potentially leading to diagnosis of preclinical lung cancer. We compared the incidence of cough-related diagnostic evaluations and lung cancer among ACEI versus angiotensin receptor blockers (ARB) initiators.
Real time evolution of non-Gaussian cumulants in the QCD critical regime
Creators: name: Mukherjee, Swagato
name: Venugopalan, Raju
name: Yin, Yi
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We derive a coupled set of equations that describe the non-equilibrium evolution of cumulants of critical fluctuations for space-time trajectories on the cross-over side of the QCD phase diagram. In particular, novel expressions are obtained for the non-equilibrium evolution of non-Gaussian Skewness and Kurtosis cumulants. Utilizing a simple model of the space-time evolution of a heavy- ion collision, we demonstrate that, depending on the relaxation rate of critical fluctuations, Skewness and Kurtosis can differ significantly in magnitude as well as in sign from equilibrium expectations. Memory effects are important and shown to persist even for trajectories that skirt the edge of the critical regime. We use phenomenologically motivated parameterizations of freeze-out curves, and of the beam energy dependence of the net baryon chemical potential, to explore the implications of our model study for the critical point search in heavy-ion collisions.
description: 16 pages, 9 figures, accepted version in Phys.Rev. C
More realistic power estimation for new user, active comparator studies: an empirical example: New User Design Power Estimation Considerations
Creators: name: Gokhale, Mugdha
name: Stürmer, Til
name: Buse, John B.
name: Pate, Virginia
name: Marquis, M. Alison
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Pharmacoepidemiologic studies are often expected to be sufficiently powered to study rare outcomes, but there is sequential loss of power with implementation of study design options minimizing bias. We illustrate this using a study comparing pancreatic cancer incidence after initiating dipeptidyl-peptidase-4 inhibitors (DPP-4i) versus thiazolidinediones or sulfonylureas.
Population dynamics of Protea nitida and Protea arborea in the Cederberg State Forest, site 3219AC/8
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
population dynamics
Protea nitida
Protea arborea
Cederberg

description: This is a scanned copy of the population dynamics of Protea nitida and Protea arborea in the Cederberg State Forest, site 3219AC/8. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species.    Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape.   SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Perineural Invasion as a Predictive Biomarker of Groin Metastases and Survival Outcomes in Vulvar Cancer: A Meta-Analysis
Creators: name: Pergialiotis, Vasilios
name: Ferousis, Loukas
name: Rouvali, Aggeliki
name: Liatsou, Efstathia
name: Haidopoulos, Dimitrios
name: Rodolakis, Alexandros
name: Thomakos, Nikolaos
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: We searched international databases to identify evidence that refer to the impact of perineural invasion on survival outcomes of patients with squamous cell vulvar cancer. We identified six retrospective cohort studies that investigated 887 patients. Of those, 234 (26.4%) had perineural invasion in the pathology analysis. Women with perineural invasion were more likely to have inguinal lymph node metastases (HR 3.45, 95% CI 1.12, 10.67). The impact of perineural invasion on progression-free survival rates was significant (HR 1.61, 95% CI 1.21, 2.15) as well as its impact on overall survival rates (HR 2.73, 95% CI 1.94, 3.84).
Injection Locking of a Semiconductor Double Quantum Dot Micromaser
Creators: name: Liu, Y. -Y.
name: Stehlik, J.
name: Gullans, M. J.
name: Taylor, J. M.
name: Petta, J. R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Emission linewidth is an important figure of merit for masers and lasers. We recently demonstrated a semiconductor double quantum dot (DQD) micromaser where photons are generated through single electron tunneling events. Charge noise directly couples to the DQD energy levels, resulting in a maser linewidth that is more than 100 times larger than the Schawlow-Townes prediction. Here we demonstrate a linewidth narrowing of more than a factor 10 by locking the DQD emission to a coherent tone that is injected to the input port of the cavity. We measure the injection locking range as a function of cavity input power and show that it is in agreement with the Adler equation. The position and amplitude of distortion sidebands that appear outside of the injection locking range are quantitatively examined. Our results show that this unconventional maser, which is impacted by strong charge noise and electron-phonon coupling, is well described by standard laser models.
Evaluation of narrowed weld pool shapes and their effect on resulting potential defects during deep penetration laser beam welding
Creators: name: Bachmann, Marcel
name: Meng, Xiangmeng
name: Artinov, Antoni
name: Rethmeier, Michael
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 530 Physik
subject: liquid metals
subject: fluid mechanics
subject: solidification process
subject: computational fluid dynamics
subject: heat transfer
subject: laser beam welding

description: This study presents mechanisms of the evolution of a narrowed region in the weld pool center during deep penetration laser beam welding. In numerous numerical studies presented in this study, it was also found that the local reduction of the weld pool size can cause detrimental effects on the melt flow behavior and the resulting properties of the welds. A particularly large influence of this effect was identified in three aspects. First, the local variation of the solidification sequence of the weld pool causes an increase in the hot-cracking susceptibility due to a locally delayed solidification. Second, it was proven that a change in the local length and width of the weld pool is associated with an adverse impact on the potential flow routes of the molten material that induces stronger local variations of its solidification. Thus, the element mixing, e.g., during the welding with filler materials, is blocked. This leads to a nonhomogeneous chemical composition of the final weld and can cause undesired effects on the final material properties. Finally, another observed effect is related to the reduced ability of process pores to reach the top surface. As this type of porosity is usually produced around the keyhole tip, the change of the fluid flow regime above this area plays a significant role in determining the final path of the pores until the premature solidification in the middle of the weld pool captures them. This study summarizes mainly numerical results that were supported by selected experimental validation results.
A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies
Creators: name: Borecki, Ingrid B.
name: Guo, Xiuqing
name: Marvel, Skylar
name: Hidalgo, Bertha
name: Claas, Steven A.
name: Srinivasasainagendra, Vinodh
name: Aslibekyan, Stella
name: Motsinger-Reif, Alison
name: Chen, Ida Y.D.
name: Ordovas, Jose M.
name: Straka, Robert J.
name: Buse, John B.
name: Irvin, Marguerite R.
name: Rotter, Jerome I.
name: Arnett, Donna K.
name: Wagner, Michael J.
name: Zhi, Degui
name: Rotroff, Daniel M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Fibrates are commonly prescribed for hypertriglyceridemia but also lower low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C). Large inter-individual variation in lipid response suggests that some persons may benefit more than others and genetic studies could help identify those persons.
Trail monitoring in Hottentots Holland, Sir Lowry's Pass, Stonehenge Trail, site 3419AA/6
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Hottentots Holland
Sir Lowry's Pass
Trail monitoring
Stonehenge Trail

description: This is a scanned copy of a document on trail monitoring in Hottentots Holland, Sir Lowry's Pass, Stonehenge Trail, site 3419AA/6. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape.  SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
The Quantum-House Effect and Its Demonstration on SpinQ Gemini
Creators: name: Varga, Tamás
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: We introduce the quantum-house effect, a non-local quantum phenomenon which goes against classical intuition. We show how the effect can be achieved with any bipartite quantum state where neither subsystem is in a pure state. Besides its theoretical description, the quantum-house effect is also demonstrated on SpinQ Gemini, a 2-qubit liquid-state NMR desktop quantum computer.
description: 17 pages, 7 figures. arXiv admin note: text overlap with arXiv:2205.12726
Dynamic changes of peripheral NK cells predict outcome in patients with PD-L1 positive Non-Small-Cell Lung Cancer undergoing immune checkpoint inhibitors as second-line therapy
Creators: name: Nelli, Fabrizio
name: Panichi, Valentina
name: Fabbri, Agnese
name: Natoni, Federica
name: Giannarelli, Diana
name: Topini, Giuseppe
name: Virtuoso, Antonella
name: Berrios, Julio Rodrigo Giron
name: Marrucci, Eleonora
name: Pessina, Gloria
name: Silvestri, Maria Assunta
name: Ruggeri, Enzo Maria
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: We evaluated immune cell frequencies in peripheral blood samples of 41 NSCLC patients before and after second-line therapy with anti-PD-1/PD-L1 agents. Changes in lymphocyte subsets and their correlation with clinical response, progression-free survival (PFS), and overall survival (OS) were analyzed. We observed an increase in median values of all lymphocyte subsets, being significant only for NK cells. A correlation was retrieved between higher post-treatment NK cell level and clinical benefit. On multivariate analysis, PD-L1 tumor proportion score ≥1% and higher post-treatment NK cell counts were predictive of longer PFS and OS. Co-presence of these factors was characterized by longer survival.
Remarks on kernel Bayes' rule
Creators: name: Johno, Hisashi
name: Nakamoto, Kazunori
name: Saigo, Tatsuhiko
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: Kernel Bayes' rule has been proposed as a nonparametric kernel-based method to realize Bayesian inference in reproducing kernel Hilbert spaces. However, we demonstrate both theoretically and experimentally that the prediction result by kernel Bayes' rule is in some cases unnatural. We consider that this phenomenon is in part due to the fact that the assumptions in kernel Bayes' rule do not hold in general.
description: 22 pages, 5 figures
Dam Removal Information Portal (DRIP)
Creators: name: Wieferich, Daniel J.
name: Duda, Jeff
name: Bristol, Sky
name: Hutchison, Vivian B.
name: Vittum, Katherine M.
name: Bellmore, James R.
name: Warrick, Jonathan
Publisher: name: U.S. Geological Survey
Year: 2016

description: The Dam Removal Information Portal (DRIP) is an online representation and visualization tool for the USGS Dam Removal Science Database, inspired by Bellmore et al. 2015 and now developed as a live data system in ScienceBase as part of the Biogeographic Information System. DRIP provides a map-based visualization of information of dam removals and associated scientific studies. The database was developed in cooperation with the NGO, American Rivers, who also provides data on other dam removals that lack associated scientific studies. The original software for the online DRIP application was developed in cooperation with AppGeo. Basic information about the dam’s location, size, date built and date removed are provided on an interactive map interface. The studies are classified in the database by type of study (physical, biological, water quality) and the measured parameters. Users can select individual dams or groups of dams and be provided citations to available scientific studies.
Basal cover line intercept surveys in Jonkershoek
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Basal cover
line intercept
Jonkershoek

description: This is a scanned copy of a document of basal cover line intercept surveys in Jonkershoek. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering
Creators: name: Onland-Moret, N. Charlotte
name: Sivapalaratnam, Suthesh
name: Munroe, Patricia B.
name: Caulfield, Mark J.
name: De Boer, Anthonius
name: Lange, Leslie A.
name: Warren, Helen R.
name: Maitland-Van Der Zee, Anke H.
name: Leusink, Maarten
name: Ding, Bo
name: Drenos, Fotios
name: Hovingh, G. Kees
name: De Bakker, Paul I.W.
name: Cushman, Mary
name: Schreiner, Pamela J.
name: Cupples, L. Adrienne
name: Van Iperen, Erik P.A.
name: Nyberg, Fredrik
name: Keating, Brendan J.
name: Kumari, Meena
name: Hingorani, Aroon D.
name: Asselbergs, Folkert W.
name: Hoogeveen, Ron C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: To find new genetic loci associated with statin response, and to investigate the association of a genetic risk score (GRS) with this outcome.
Spin-dependent current through a quantum dot from spin-polarized non-equilibrium quantum Hall edge channels
Creators: name: Kiyama, Haruki
name: Nakajima, Takashi
name: Teraoka, Soichiro
name: Oiwa, Akira
name: Tarucha, Seigo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report selective injection of both spin-up and spin-down single electrons into a quantum dot (QD) from spin-polarized non-equilibrium quantum Hall edge channels (ECs) generated by selective transmission of spin-resolved ECs using a surface gate placed at a distance from the QD. We change the spin polarization of non-equilibrium ECs by changing the bias voltages applied to different source Ohmic contacts. The efficiency of spin-up electron injection reaches 0.5, which is approximately 0.2 higher than that induced by spin-dependent tunnel coupling between QD and ECs. On the other hand, the efficiency of spin-down electron injection reaches 0.4. In addition, we rectify the underestimation of the efficiency of spin filtering for equilibrium ECs by numerically subtracting the contribution of the excited states in the QD. The obtained spin-filtering efficiency is higher than that evaluated from the raw experimental data and increases with magnetic field as expected with the increase in the spatial separation between ECs.
description: 8 pages, 7 figures
Patterns of Detachment: Spatial Transformations of the Phosphate Industry in el-Quseir, Egypt
Creators: name: Damir, Mirhan
name: Meyer, Martin
name: Aziz, Hellen
Publisher: name: Technische Universität Berlin
Year: 2023
Subjects: subject: 710 Städtebau, Raumplanung, Landschaftsgestaltung
subject: Egypt
subject: industrial heritage
subject: industrialization
subject: Italy
subject: mining
subject: phosphate industry

description: The establishment of phosphate mines and processing plants by Italian entrepreneurs in el-Quseir in 1912 revitalized a town that had faced a steady decline after the opening of the Suez Canal and re-linked it to the world economy. To this day, the now defunct industrial site occupies a large section of physical el-Quseir and plays a key role in its identity. In this article, we explore the impact of the company’s successive industrialization and deindustrialization based on archival research, interviews, and mapping. By tracing physical changes on-site and in the city of el-Quseir from the founding of its phosphate industry until today, as well as the historical and current interactions of citizens with the industrial facilities, we hope to better understand the “cluster value” of the industrial plant in quotidian life and the effect of the vacuum left behind after the termination of production. As machinery and buildings are slowly eroding in the absence of expressed interest by the former Italian and current Egyptian owners, we aim to discuss the relationship between the citizens and their el-Quseir phosphate plant as a crucial element of its heritage value at the local level.
Integrated Water Management and Ethics in Africa – Case study I: Drarga Village Wastewater Treatment project, Morocco
Creators: name: Lahcen EL YOUSSFI
name: Moseki Ronald MOTSHOLAPHEKO
name:  Oghenekaro Nelson  ODUME
name: Nosiphiwe  NGQWALA
name: GUNN, Elena LOPEZ
name: HEBINCK, Paul
name: WET, Chris DE
Publisher: name: AAS Open Research
Year: 2020

description: Abstract:
One of the crucial and dismissed aspects related to IWRM (integrated water resource management) strategies in Africa and globally especially in regions characterized by a domination of arid and semi arid climate, is the ethical issue Thus, even with the adoption of IWRM strategies and development in water resource policy, regulation, law, management, monitoring, health and research in water resources sector, there are still many challenges. Those challenges are related to poverty, inequality, social and environmental injustices that pervade the concerned territories In fact, sustainable use and protection of water resources are essential for addressing some of these social challenges How can equity, and social and environmental justice, in its broad sense of including human and ecological constituencies, are achieved in the allocation of water and in the management of water resources? This work aims to draw an overview on the ethics issue and values related to water resources management by proposing a Systemic Relational ( perspective This perspective will be applied at different levels using case studies within the context of IWRM in Africa and Globally This poster presents the case study of Drarga wastwater reatment project in Morocco.
Identifying genetic loci affecting antidepressant drug response in depression using drug–gene interaction models
Creators: name: Stricker, Bruno H.
name: Visser, Loes E.
name: Avery, Christy L.
name: Noordam, Raymond
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Antidepressants are often only moderately successful in decreasing the severity of depressive symptoms. In part, antidepressant treatment response in patients with depression is genetically determined. However, although a large number of studies have been conducted aiming to identify genetic variants associated with antidepressant drug response in depression, only a few variants have been repeatedly identified. Within the present review, we will discuss the methodological challenges and limitations of the studies that have been conducted on this topic to date (e.g., ‘treated-only design’, statistical power) and we will discuss how specifically drug–gene interaction models can be used to be better able to identify genetic variants associated with antidepressant drug response in depression.
On phase separation in systems of coupled elliptic equations: asymptotic analysis and geometric aspects
Creators: name: Soave, Nicola
name: Zilio, Alessandro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We consider a family of positive solutions to the system of $k$ components \[ -Δu_{i,β} = f(x, u_{i,β}) - βu_{i,β} \sum_{j \neq i} a_{ij} u_{j,β}^2 \qquad \text{in $Ω$}, \] where $Ω\subset \mathbb{R}^N$ with $N \ge 2$. It is known that uniform bounds in $L^\infty$ of $\{\mathbf{u}_β\}$ imply convergence of the densities to a segregated configuration, as the competition parameter $β$ diverges to $+\infty$. In this paper %we study more closely the asymptotic property of the solutions of the system in this singular limit: we establish sharp quantitative point-wise estimates for the densities around the interface between different components, and we characterize the asymptotic profile of $\mathbf{u}_β$ in terms of entire solutions to the limit system \[ ΔU_i = U_i \sum_{j\neq i} a_{ij} U_j^2. \] Moreover, we develop a uniform-in-$β$ regularity theory for the interfaces.
description: 33 pages, some correction with respect to the previous version
title: MRI to evaluate the effectiveness of enzyme replacement therapy in type 1 Gaucher's disease patients
Creators: name: Rabelo, Breno
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Bones
subject: Musculoskeletal system
subject: Musculoskeletal bone
subject: MR
subject: Absorptiometry / Bone densitometry
subject: MR-Diffusion/Perfusion
subject: Dosimetry
subject: Physics
subject: Treatment effects
subject: Drugs / Reactions
subject: Pathology
subject: Metabolic disorders

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: The purpose of this study was to evaluate the effectiveness of enzyme replacement therapy (ERT) in patients with type 1 Gaucher disease with a quantitative method obtained by a 3D T2*-corrected Dixon sequence in a cohort of patients with Gaucher's...
Modeling Bends in Popular Music Guitar Tablatures
Creators: name: D'Hooge, Alexandre
name: Bigo, Louis
name: Déguernel, Ken
Publisher: name: arXiv
Year: 2023
Subjects: subject: Sound (cs.SD)
subject: Artificial Intelligence (cs.AI)
subject: Multimedia (cs.MM)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Tablature notation is widely used in popular music to transcribe and share guitar musical content. As a complement to standard score notation, tablatures transcribe performance gesture information including finger positions and a variety of guitar-specific playing techniques such as slides, hammer-on/pull-off or bends.This paper focuses on bends, which enable to progressively shift the pitch of a note, therefore circumventing physical limitations of the discrete fretted fingerboard. In this paper, we propose a set of 25 high-level features, computed for each note of the tablature, to study how bend occurrences can be predicted from their past and future short-term context. Experiments are performed on a corpus of 932 lead guitar tablatures of popular music and show that a decision tree successfully predicts bend occurrences with an F1 score of 0.71 anda limited amount of false positive predictions, demonstrating promising applications to assist the arrangement of non-guitar music into guitar tablatures.
Two-epoch centimeter-level PPP-RTK without external atmospheric corrections using best integer-equivariant estimation
Creators: name: Brack, Andreas
name: Männel, Benjamin
name: Schuh, Harald
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 550 Geowissenschaften
subject: multi-GNSS
subject: precise point positioning
subject: PPP
subject: integer ambiguity resolution
subject: best integer-equivariant estimation
subject: PPP-AR
subject: PPP-RTK

description: Ambiguity resolution enabled precise point positioning (PPP-AR or PPP-RTK) without atmospheric corrections requires the user to estimate tropospheric and ionospheric delay parameters. The presence of the unconstrained ionosphere parameters impedes fast and reliable ambiguity resolution, so a time-to-first-fix of around 30 min for GPS-only solutions is generally reported, which can, to some extent, be reduced when combining multiple GNSS. In this contribution, we investigate the capabilities of almost instantaneous PPP-RTK, using only a few observation epochs at a sampling interval of 30 s, with the ionosphere-float model. The considered key elements are (a) the MSE-optimal best integer-equivariant estimator, (b) a combination of dual-frequency GPS, Galileo, BDS, and QZSS, (c) an area with good visibility of BDS and QZSS, and (d) a proper weighting of the PPP-RTK corrections. We provide a formal and simulation-based analysis of kinematic and static PPP-RTK with perfect, i.e., deterministic, clock and bias corrections as well as corrections computed from only a single reference station. The results indicate that, on average, one can expect centimeter-level positioning results with just slightly more than two epochs already with single-station corrections. This is confirmed with real four-system GNSS data, for which the availability of two-epoch centimeter-level horizontal positioning results is 99.7% during an exemplary day.
Non-hormonal male contraception: A review and development of an Eppin based contraceptive
Creators: name: O'Rand, Michael G.
name: Silva, Erick J.R.
name: Hamil, Katherine G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Developing a non-hormonal male contraceptive requires identifying and characterizing an appropriate target and demonstrating its essential role in reproduction. Here we review the development of male contraceptive targets and the current therapeutic agents under consideration. In addition, the development of EPPIN as a target for contraception is reviewed. EPPIN is a well characterized surface protein on human spermatozoa that has an essential function in primate reproduction. EPPIN is discussed as an example of target development, testing in non-human primates, and the search for small organic compounds that mimic contraceptive antibodies; binding EPPIN and blocking sperm motility. Although many hurdles remain before the success of a non-hormonal male contraceptive, continued persistence should yield a marketable product.
title: Benign Pathology of Myometrium - Pictorial Review and Clues to Expanding the Differential Diagnosis
Creators: name: Dionisio, Teresa
Publisher: name: European Congress of Radiology
Year: 2016
Subjects: subject: Education and training
subject: Education
subject: Diagnostic procedure
subject: Ultrasound
subject: MR
subject: CT
subject: Pelvis
subject: Genital / Reproductive system female

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: – To provide a pictorial review of benign myometriallesions with pathologic correlation; – To review the clinical manifestations, radiological findings and differential diagnosis ofbenign myometrial...
Investigating Galaxy-Filament Alignments in Hydrodynamic Simulations using Density Ridges
Creators: name: Chen, Yen-Chi
name: Ho, Shirley
name: Tenneti, Ananth
name: Mandelbaum, Rachel
name: Croft, Rupert
name: DiMatteo, Tiziana
name: Freeman, Peter E.
name: Genovese, Christopher R.
name: Wasserman, Larry
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Applications (stat.AP)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: In this paper, we study the filamentary structures and the galaxy alignment along filaments at redshift $z=0.06$ in the MassiveBlack-II simulation, a state-of-the-art, high-resolution hydrodynamical cosmological simulation which includes stellar and AGN feedback in a volume of (100 Mpc$/h$)$^3$. The filaments are constructed using the subspace constrained mean shift (SCMS; Ozertem & Erdogmus (2011) and Chen et al. (2015a)). First, we show that reconstructed filaments using galaxies and reconstructed filaments using dark matter particles are similar to each other; over $50\%$ of the points on the galaxy filaments have a corresponding point on the dark matter filaments within distance $0.13$ Mpc$/h$ (and vice versa) and this distance is even smaller at high-density regions. Second, we observe the alignment of the major principal axis of a galaxy with respect to the orientation of its nearest filament and detect a $2.5$ Mpc$/h$ critical radius for filament's influence on the alignment when the subhalo mass of this galaxy is between $10^9M_\odot/h$ and $10^{12}M_\odot/h$. Moreover, we find the alignment signal to increase significantly with the subhalo mass. Third, when a galaxy is close to filaments (less than $0.25$ Mpc$/h$), the galaxy alignment toward the nearest galaxy group depends on the galaxy subhalo mass. Finally, we find that galaxies close to filaments or groups tend to be rounder than those away from filaments or groups.
description: 11 pages, 10 figures
ESiWACE2 Exploitation Plan (D7.5)
Creators: name: ESiWACE2 Project Office
Publisher: name: Zenodo
Year: 2019
Subjects: ESiWACE2

description: This deliverable summarises the beneficiaries’ strategy and concrete actions related to the protection and exploitation of the project results.
 Horizon 2020 is a Research and Innovation programme aiming at fostering competitiveness and growth and increasing benefits to the European Union economy and citizens. Public investment in projects are to be converted into socio‐economic benefits for the society, as clearly indicated in the Horizon 2020 Rules for Participation1, with a clear accent to the beneficiaries’ obligations to exploit and disseminate the outcomes of the funded activities. The Horizon 2020 work programme for this call explicitly specified that project proposals shall include a draft Plan for the Exploitation of Results. The plan is a strategic document indicating how the partnership establishes the basis for the intellectual property (IP) strategy and exploitation activities, and summarises the beneficiaries’ strategy and concrete actions related to the protection and exploitation of the project results.