cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Eurytion Attems 1903
Creators: name: Pereira, Luis A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Chilopoda
Geophilomorpha
Geophilidae
Eurytion

description: Genus Eurytion Attems, 1903
Diagnosis: Clypeal area finely punctate or granulate, not areolate. First maxillae with or without coxosternal lappets, telopodite lappets present. Second maxillae with coxosternites medially joined through a narrow, hyaline and non­areolate membranous isthmus only; antero­internal corners of coxosternum without processes; coxosternal pore surronded by sclerotized rim. Forcipulae: pleurocoxosternal sutures extend parallel to the outer margin, chitinous lines absent. Sterna with pore fields. Last pair of legs with two tarsal articles; praetarsus of last legs claw­like, well developed; coxopleura of the last leg­bearing segment with numerous coxal organs opening separately or grouped in one or two clusters.
Type of the genus: Geophilus (Eurytion) michaelseni Attems, 1903 (currently Eurytion michaelseni (Attems, 1903)) by subsequent designation by Attems 1929 —Tierreich 52: 254.
Remark: For a complete list of the Neotropical species currently included in the genus Eurytion and corresponding full citations, see Foddai, Pereira and Minelli (2000).
description: Published as part of Pereira, Luis A., 2005, A new geophilid centipede of the genus Eurytion Attems, 1903 from north­western Argentina. (Chilopoda: Geophilomorpha: Geophilidae), pp. 1-12 in Zootaxa 794 on pages 2-3, DOI: 10.5281/zenodo.170535
Influence of processing on the microstructure of aerospace ceramics by imaging
Creators: name: Campos de Oliveira, Paula
name: Zhang, Wen
name: Markötter, Henning
name: Remacha, Clément
name: Bruno, Giovanni
Publisher: name: Zenodo
Year: 2024
Subjects: Microstructure
silica-based ceramics
tomography
synchrotron

description: Influence of processing on the microstructure of aerospace ceramics by imaging
On the possible core shift break in relativistic jets
Creators: name: Nokhrina, E. E.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Measurement of a jet geometry transition region is an important instrument of assessing the jet ambient medium properties, plasma bulk motion acceleration, parameters of a black hole and location of a jet launching radius. In this work we explore the possibility of a presence of a core shift break, associated with the geometry and jet physical properties transition. We obtain the relations on the core shift offset jump due to a change in a core shift exponent. The condition of a proper frame magnetic field continuity and the core shift break can be used as an instrument to refine the magnetic field estimates upstream the break. This method is applied to the jet in NGC 315. We speculate that the localised in a flow plasma heating either by reconnection or due to particles acceleration at the shock will also lead to a core shift break, but of a different type, than the one observed in NGC 315. We propose to use the multi-frequency core shift measurements to increase the number of sources with a detected jet shape break and to boost the accuracy of assessing the properties of a jet geometry transition region.
description: 11 pages, 3 figures. Accepted by MNRAS 2024 November 5
Mickelomyrme palawanensis
Creators: name: Lelej, A. S.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Mutillidae
Mickelomyrme
Mickelomyrme palawanensis

description: Mickelomyrme palawanensis (Miclel, 1934)
Smicromyrme palawanensis Mickel, 1934: 206, ♂, type locality: " Puerto Princesa " (Philippines: Palawan) [USNM]; Tsuneki et al., 1993: 20, Figs 59–64, ♂.
Mickelomyrme palawanensis: Lelej, 2005: 44, ♂; Pagliano et al., 2020: 175.
MATERIAL EXAMINED. Indonesia: Lombok, near Senggigi, 450 m, forest, 8º28ʹ31.9ʺS 116º2ʹ57.8ʺE, 9.V 2012, 1♂ (MM); same place, 21, 22.V 2012, 3♂ (MM); Senggigi, hotel, 8º28ʹ58.6ʺS 116º2ʹ12.9ʺE, 14.V 2012, 1♂ (MM); Lombok, Kokok Putih River, 8º15ʹ19.3ʺS 116º28ʹ38.5ʺE, 20.V 2012, 2♀, 1♂ (MM).
DISTRIBUTION. Indonesia * (Lombok), Philippines (Palawan, Mindanao).
REMARKS. The differences between the female of M. palawanensis and the female of M. zebina can be seen in the key above. Collecting females and males at the same site on Lombok allows me to treat them as opposite sexes of the same species. There is no direct evidence (pair collected in copula) to support this relationship. It is possible that the female of Smicromyrme aborlana Tsuneki, 1993 described from Palawan (Tsuneki et al., 1993), which is similar to the female of M. palawanensis (Mickel, 1934) collected on Lombok, is a synonym of the latter.
description: Published as part of Lelej, A. S., 2024, REVIEW OF THE VELVET ANTS (HYMENOPTERA: MUTILLIDAE) OF WALLACEA WITH SPECIAL REFERENCE TO LOMBOK, INDONESIA, pp. 1-25 in Far Eastern Entomologist 504 on page 9, DOI: 10.25221/fee.504.1, http://zenodo.org/record/14658603
Terebra obesa Hinds 1844
Creators: name: Salvador, Andreia
name: Pickering, Joan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Terebridae
Terebra
Terebra obesa

description: Terebra obesa Hinds, 1844
Hinds, 1844: 158.
Type locality: ‘-?’.
Label locality: ‘-?’.
Type material: Holotype NHMUK 1968250 (H. Cuming collection).
description: Published as part of Salvador, Andreia & Pickering, Joan, 2017, Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K., pp. 101-142 in Zootaxa 4250 (2) on page 128, DOI: 10.11646/zootaxa.4250.2.1, http://zenodo.org/record/450745
Smicromyrme brothersi Lelej, 2024, sp. n.
Creators: name: Lelej, A. S.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Mutillidae
Smicromyrme
Smicromyrme brothersi

description: Smicromyrme brothersi sp. n.
https://zoobank.org/NomenclaturalActs/ 846A310C-56E9-47D9-8D1C-25F97368C027
Figs 9–11
MATERIAL EXAMINED. Holotype ♀, Indonesia, Lombok, near Senggigi, 450 m, forest, 8º28ʹ31.9ʺS 116º2,96ʹE, 18.V 2012 (MM) [IBSS]. Paratypes, same place, 9.V 2012, 1♀ (MM); 18.V 2012, 4♀ (MM); same place, 22.V 2012, 1♀ (MM).
DIAGNOSIS. FEMALE. Differs from all oriental congeners in the absence of the medial basal spot on T2. MALE. Unknown.
DESCRIPTION. FEMALE. Body length 4.8-6.0 mm. Head black, brownish beneath, mandible, clypeus and antenna largely brown. Mesosoma ferruginous, femora and tibia brownish. Metasoma black. Body setae generally sparse and silvery, except vertex, T2 and T4-5 with blackish setae; mesosomal dorsum with reddish setae and T1 apex, T2 apical band, T3 entire and T6 laterally with dense whitish-silvery setae. Head. Width behind eye equal to width of pronotum. Frons, vertex and genae with separate punctures. Mandibular apex obscurely bidentate. Clypeus with narrow, transversely medially emargined lamella; basomedial part with carinae forming tubercle. Antennal scrobe without dorsal carina. Antennal tubercle smooth. Genal carina obliterated. F1 1.2 × pedicel length, F2 1.3 × pedicel length. Mesosoma. Length 1.3 × maximum width. Dorsum of mesosoma with coarse confluent punctures. Side of mesosoma with scattered moderate punctures with appressed setae, interspaces mostly smooth, propodeal side with distinct reticulation posteriorly. Mesopleural lamella absent. Humeral carina simple, rounded dorsally. Scutellar scale transversely arcuate, ~4 punctures wide. Lateral and posterior propodeal surfaces separated by slightly wavy carina. Metasoma. T1- 5 with small dense punctures, less on T1. S1 with simple longitudinal carina. T2 felt line 0.5 × total length of T2. T6 with long ovate pygidium; with parallel striae (16 at widest point), posterior fifth smooth. S6 posterior margin bidentate.
DISTRIBUTION. Indonesia (Lombok).
ETYMOLOGY. I am pleased to name this new species in honour of Denis Brothers, world authority on the classification and evolution of Mutillidae and Aculeate and my best colleague. Treat as noun in apposition.
description: Published as part of Lelej, A. S., 2024, REVIEW OF THE VELVET ANTS (HYMENOPTERA: MUTILLIDAE) OF WALLACEA WITH SPECIAL REFERENCE TO LOMBOK, INDONESIA, pp. 1-25 in Far Eastern Entomologist 504 on pages 10-11, DOI: 10.25221/fee.504.1, http://zenodo.org/record/14658603
Additional file 1: of A set of systematic reviews to help reduce inappropriate prescribing to older people: study protocol
Creators: name: Martinez, Yolanda
name: Renom-Guiteras, Anna
name: Reeves, David
name: R. Erandie Ediriweera De Silva
name: Aneez Esmail
name: Kunnamo, Ilkka
name: Rieckert, Anja
name: Sommerauer, Christina
name: SĂśnnichsen, Andreas
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Protocol template. (DOCX 51Â kb)
Emergence of steady quantum transport in a superconducting processor
Creators: name: Zhang, Pengfei
name: Gao, Yu
name: Xu, Xiansong
name: Wang, Ning
name: Dong, Hang
name: Guo, Chu
name: Deng, Jinfeng
name: Zhang, Xu
name: Chen, Jiachen
name: Xu, Shibo
name: Wang, Ke
name: Wu, Yaozu
name: Zhang, Chuanyu
name: Jin, Feitong
name: Zhu, Xuhao
name: Zhang, Aosai
name: Zou, Yiren
name: Tan, Ziqi
name: Cui, Zhengyi
name: Zhu, Zitian
name: Shen, Fanhao
name: Li, Tingting
name: Zhong, Jiarun
name: Bao, Zehang
name: Zhao, Liangtian
name: Hao, Jie
name: Li, Hekang
name: Wang, Zhen
name: Song, Chao
name: Guo, Qiujiang
name: Wang, H.
name: Poletti, Dario
Publisher: name: arXiv
Year: 2024
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Non-equilibrium quantum transport is crucial to technological advances ranging from nanoelectronics to thermal management. In essence, it deals with the coherent transfer of energy and (quasi-)particles through quantum channels between thermodynamic baths. A complete understanding of quantum transport thus requires the ability to simulate and probe macroscopic and microscopic physics on equal footing. Using a superconducting quantum processor, we demonstrate the emergence of non-equilibrium steady quantum transport by emulating the baths with qubit ladders and realising steady particle currents between the baths. We experimentally show that the currents are independent of the microscopic details of bath initialisation, and their temporal fluctuations decrease rapidly with the size of the baths, emulating those predicted by thermodynamic baths. The above characteristics are experimental evidence of pure-state statistical mechanics and prethermalisation in non-equilibrium many-body quantum systems. Furthermore, by utilising precise controls and measurements with single-site resolution, we demonstrate the capability to tune steady currents by manipulating the macroscopic properties of the baths, including filling and spectral properties. Our investigation paves the way for a new generation of experimental exploration of non-equilibrium quantum transport in strongly correlated quantum matter.
description: 7 pages, 4 figures
Terebra pallida Deshayes 1857
Creators: name: Salvador, Andreia
name: Pickering, Joan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Terebridae
Terebra
Terebra pallida

description: Terebra pallida Deshayes, 1857
Deshayes, 1857: 87, pl. 4, fig. 3.
Type locality: ‘Les Ȋles Marquises’.
Label locality: ‘ Isles Marquesas’.
Type material: Lectotype NHMUK 197967/1 and 2 paralectotypes NHMUK 197967/2-3 (H. Cuming collection). Indirect lectotype selection by inference of holotype (Cernohorsky, 1969: 218).
description: Published as part of Salvador, Andreia & Pickering, Joan, 2017, Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K., pp. 101-142 in Zootaxa 4250 (2) on page 128, DOI: 10.11646/zootaxa.4250.2.1, http://zenodo.org/record/450745
Enantioselective electrochemical detection of a L-and D-serine at polyvinylpyrrolidone-modified platinum electrode
Creators: name: Amayreh, Mohammad
name: Hourani, Mohammed Khair
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Aim: By modifying the Pt electrode with polyvinylpyrrolidone, the distinct oxidation potentials of L and D-serine were markedly increased for both isomers. Methods & results: CV was used for Pt electrode modification with PVP. Twenty cycles was reasonable for Pt modification. K3[Fe(CN)6] CV experiments investigated reversibility of the Fe(III) redox reaction and the enhancement of electron transfer at the PVP-Pt electrode. L and D-serine showing an oxidation peak potential at 0.394 V and 0.468 V, respectively. A linear relationship between the anodic oxidation current extracted from the CVs and the standard concentrations of L-serine and D-serine solutions was obtained with R2 = 0.99. The dynamic range for D-serine was from 0.5 to 20 mM with a LOD of 0.16 mM, while for L-serine, was from 2.5 to 20 mM with a detection limit of 0.27 mM. Using DPV, the dynamic range was 0.05–1.0 µM for D-serine with a detection limit of 0.0103 µM. The standard deviation ranged from 0.212 to 0.38 across ten determinations per concentration. Conclusion: A separation by 74 mV between the oxidation peaks of L and D-serine was achieved with remarkable enhancement in oxidation current for both isomers. PVP-Pt electrode can detect D-serine in the presence of DL-serine. The platinum electrode was modified using polyvinylpyrrolidone (PVP), which significantly enhanced the oxidation of L-serine and D-serine, making the modified electrode more effective for detecting these amino acid isomers. Cyclic voltammetry (CV) experiments revealed separate oxidation potentials for L-serine (0.394 V) and D-serine (0.468 V), resulting in a 74 mV difference. The modified PVP-Pt electrode demonstrated better reversibility in the Fe(III) redox reaction during CV with K3[Fe(CN)6], reducing the peak-to-peak separation (ΔEP) from 0.15 V to 0.09 V compared with the unmodified electrode. Differential pulse voltammetry (DPV) achieved a lower dynamic range of 0.05 to 1.0 µM D-serine with a detection limit of 0.0103 µM.
Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique
Creators: name: Said, Rana
name: Ghazzy, Asma
name: Shakya, Ashok K.
name: Al hunaiti, Afnan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Iron oxide nanozymes (IONzymes) have become fundamental components in various analyte detection methodologies such as colorimetric, electrochemistry, fluorescence and luminescence. Their tunability, stability and the possibility of modification, alongside their ability to mimic the catalytic properties of natural enzymes like peroxidase, render them invaluable in analytical chemistry. This review explores the diverse applications of IONzymes across analytical chemistry, with a particular highlighting on their roles in different detection techniques and their potential in biomedical and diagnostic applications. This information would be valuable for researchers and practitioners in the fields of analytical chemistry, biochemistry, biotechnology and materials science who are interested in applying IONzymes in their work. In essence, this review article on iron oxide nanozymes in analytical chemistry would serve as a valuable resource for researchers, educators and industry professionals, offering insights, guidance and inspiration for further study and application of this promising class of nanomaterials. Iron oxide nanozymes exhibit catalytic properties that simulate natural enzymes, making them valuable in analytical applications. The variety of iron oxide nanozymes is leading to their widespread use as detection tools in various fields, from biosensing to environmental monitoring. These nanozymes possess enzyme-mimicking activities, including oxidase, peroxidase and catalase-like behaviors, which make them fitting for a range of analytical applications. Iron oxide nanozymes have been successfully employed in colorimetric, electrochemical and fluorescence-based detection techniques. Their capability to catalyze reactions without the limitations of natural enzymes makes them highly stable and effective for detection in various samples. Present challenges include enhancing the selectivity and sensitivity of nanozyme-based detection systems. Future research is expected to focus on developing novel hybrid nanozymes and improving their biocompatibility for use in practical everyday life situations.
MOESM5 of Malaria risk factors and care-seeking behaviour within the private sector among high-risk populations in Vietnam: a qualitative study
Creators: name: Chen, Ingrid
name: Thanh, Huong
name: Lover, Andrew
name: Thao, Phung
name: Luu, Tang
name: Thang, Hoang
name: Ngo Thang
name: Neukom, Josselyn
name: Bennett, Adam
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Additional file 5. Provider antimalarial/malaria rapid diagnostic test stock form.
Control of Biohybrid Actuators using NeuroEvolution
Creators: name: Alcaraz-Herrera, Hugo
name: Tsompanas, Michail-Antisthenis
name: Adamatzky, Andrew
name: Balaz, Igor
Publisher: name: arXiv
Year: 2024
Subjects: subject: Robotics (cs.RO)
subject: Emerging Technologies (cs.ET)
subject: FOS: Computer and information sciences

description: In medical-related tasks, soft robots can perform better than conventional robots because of their compliant building materials and the movements they are able perform. However, designing soft robot controllers is not an easy task, due to the non-linear properties of their materials. Since human expertise to design such controllers is yet not sufficiently effective, a formal design process is needed. The present research proposes neuroevolution-based algorithms as the core mechanism to automatically generate controllers for biohybrid actuators that can be used on future medical devices, such as a catheter that will deliver drugs. The controllers generated by methodologies based on Neuroevolution of Augmenting Topologies (NEAT) and Hypercube-based NEAT (HyperNEAT) are compared against the ones generated by a standard genetic algorithm (SGA). In specific, the metrics considered are the maximum displacement in upward bending movement and the robustness to control different biohybrid actuator morphologies without redesigning the control strategy. Results indicate that the neuroevolution-based algorithms produce better suited controllers than the SGA. In particular, NEAT designed the best controllers, achieving up to 25% higher displacement when compared with SGA-produced specialised controllers trained over a single morphology and 23% when compared with general purpose controllers trained over a set of morphologies.
Terebra (Leiostoma) parva Baird in Brenchley 1873
Creators: name: Salvador, Andreia
name: Pickering, Joan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Terebridae
Terebra
Terebra parva

description: Terebra (Leiostoma) parva Baird in Brenchley, 1873
Baird in Brenchley, 1873: 435.
Type locality: ‘New Caledonia’.
Label locality: ‘ New Caledonia’.
Type material: Lectotype NHMUK 1979153 and 1 paralectotype NHMUK 1979154 (J. Brenchley collection). Lectotype selection (Cernohorsky, 1969: 218).
description: Published as part of Salvador, Andreia & Pickering, Joan, 2017, Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K., pp. 101-142 in Zootaxa 4250 (2) on pages 128-129, DOI: 10.11646/zootaxa.4250.2.1, http://zenodo.org/record/450745
Additional file 4: of
                     Trypanosoma cruzi specific mRNA amplification by in vitro transcription improves parasite transcriptomics in host-parasite RNA mixtures
Creators: name: Kessler, Rafael
name: Pavoni, Daniela
name: Krieger, Marco
name: Probst, Christian
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Contains all supplemental figures (Figures S1 to S5) and tables (Table S1 and S2). (DOCX 1811Â kb)
Halictoxenos tumulorum Perkins 1918
Creators: name: Ostrovsky, A. M.
name: Ivlev, K. S.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Strepsiptera
Stylopidae
Halictoxenos
Halictoxenos tumulorum

description: Halictoxenos tumulorum Perkins, 1918
Fig. 1
MATERIAL EXAMINED. Russia: Kursk Oblast, 18.7 km SW of Kursk, near vill. Berezka, Central Chernozem Nature biosphere reserve named after V. V. Alekhin, Streleckaya step, Dedov Vesely, 51.566494°N, 36.107151°E, the edge of the forest, 12.VIII 2022, K.S. Ivlev leg. – 1♂ of Halictus (Monilapis) simplex Blüthgen, 1923 (K.S. Ivlev det. (rechecked by Yu. V. Astafurova)) stylopized by 1♀ of Halictoxenos. tumulorum (between IV and V sternites) (A.M. Ostrovsky det.).
DISTRIBUTION. Widely distributed in central and southern Europe, also extending to the Near East and North Africa, currently known from Italy (type locality), Austria, Canary Islands, Czech Republic, Great Britain, Finland, France, Germany, Hungary, Ireland, Italy, Netherlands, Portugal, Slovakia, Turkey, Ukraine, Belgium, Estonia and the North-western part of European Russia (Pohl 2010; Soon et al., 2011; Cook, 2019).
REMARKS. Three known European Halictoxenos species are highly specialized parasites of bees from the genus Halictus (Hymenoptera: Halictidae). Halictoxenos tumulorum is the only known Stepsiptera parasite of the Halictus subgenus Seladonia, including H. (S.) kessleri Bramson 1879 and H. (S.) tumulorum (Linnaeus, 1758), as well as H. (Monilapis) simplex Blüthgen, 1923 (Cook, 2019), which is a common and widespread species in European Russia (Kinzelbach, 1978).
description: Published as part of Ostrovsky, A. M. & Ivlev, K. S., 2024, NEW RECORDS OF STYLOPIDS (STREPSIPTERA: STYLOPIDAE) FROM THE EUROPEAN PART OF RUSSIA, pp. 26-32 in Far Eastern Entomologist 504 on page 27, DOI: 10.25221/fee.504.2, http://zenodo.org/record/14658589
Additional file 2: Table S2A. of Personalized treatment of women with early breast cancer: a risk-group specific cost-effectiveness analysis of adjuvant chemotherapy accounting for companion prognostic tests OncotypeDX and Adjuvant!Online
Creators: name: Jahn, Beate
name: Rochau, Ursula
name: Kurzthaler, Christina
name: Hubalek, Michael
name: Miksad, Rebecca
name: Sroczynski, Gaby
name: Paulden, Mike
name: Bundo, Marvin
name: Stenehjem, David
name: Brixner, Diana
name: Krahn, Murray
name: Siebert, Uwe
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: Plant Biology

description: Sensitivity Analysis of cost effectiveness of chemotherapy in subgroups with a low risk according to OncotypeDX. “Table S2A” is referring to Table 2a: “Sensitivity Analysis of cost effectiveness of chemotherapy in subgroups with a low risk according to OncotypeDX”. (DOCX 18 kb)
Enantioselective electrochemical detection of a L-and D-serine at polyvinylpyrrolidone-modified platinum electrode
Creators: name: Amayreh, Mohammad
name: Hourani, Mohammed Khair
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Aim: By modifying the Pt electrode with polyvinylpyrrolidone, the distinct oxidation potentials of L and D-serine were markedly increased for both isomers. Methods & results: CV was used for Pt electrode modification with PVP. Twenty cycles was reasonable for Pt modification. K3[Fe(CN)6] CV experiments investigated reversibility of the Fe(III) redox reaction and the enhancement of electron transfer at the PVP-Pt electrode. L and D-serine showing an oxidation peak potential at 0.394 V and 0.468 V, respectively. A linear relationship between the anodic oxidation current extracted from the CVs and the standard concentrations of L-serine and D-serine solutions was obtained with R2 = 0.99. The dynamic range for D-serine was from 0.5 to 20 mM with a LOD of 0.16 mM, while for L-serine, was from 2.5 to 20 mM with a detection limit of 0.27 mM. Using DPV, the dynamic range was 0.05–1.0 µM for D-serine with a detection limit of 0.0103 µM. The standard deviation ranged from 0.212 to 0.38 across ten determinations per concentration. Conclusion: A separation by 74 mV between the oxidation peaks of L and D-serine was achieved with remarkable enhancement in oxidation current for both isomers. PVP-Pt electrode can detect D-serine in the presence of DL-serine. The platinum electrode was modified using polyvinylpyrrolidone (PVP), which significantly enhanced the oxidation of L-serine and D-serine, making the modified electrode more effective for detecting these amino acid isomers. Cyclic voltammetry (CV) experiments revealed separate oxidation potentials for L-serine (0.394 V) and D-serine (0.468 V), resulting in a 74 mV difference. The modified PVP-Pt electrode demonstrated better reversibility in the Fe(III) redox reaction during CV with K3[Fe(CN)6], reducing the peak-to-peak separation (ΔEP) from 0.15 V to 0.09 V compared with the unmodified electrode. Differential pulse voltammetry (DPV) achieved a lower dynamic range of 0.05 to 1.0 µM D-serine with a detection limit of 0.0103 µM.
Additional file 4: of
                     Trypanosoma cruzi specific mRNA amplification by in vitro transcription improves parasite transcriptomics in host-parasite RNA mixtures
Creators: name: Kessler, Rafael
name: Pavoni, Daniela
name: Krieger, Marco
name: Probst, Christian
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Contains all supplemental figures (Figures S1 to S5) and tables (Table S1 and S2). (DOCX 1811Â kb)
Hylecthrus rubi Saunders 1850
Creators: name: Ostrovsky, A. M.
name: Ivlev, K. S.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Strepsiptera
Stylopidae
Hylecthrus
Hylecthrus rubi

description: Hylecthrus rubi Saunders, 1850
Fig 2
MATERIAL EXAMINED. Russia: Lipetsk Oblast, Zadonsk Dist., 40 km E of the vill. Donskoye, Galichya Gora Nature Reserve, Morozova Gora, 52.600240°N, 38.925229°E, 28.VIII 2019, O.N. Berezhnova leg. – 1♂ of Hylaeus (Lambdopsis) annularis (Kirby, 1802) (K.S. Ivlev det. (it was compared by copies, rechecked by A. Z. Osychnyuk)) stylopized by 1♀ of Hylecthrus rubi (between IV and V tergites) (A.M. Ostrovsky det.).
DISTRIBUTION. Widely distributed in Europe and extending to the Middle East, currently known from Albania, Austria, Bulgaria, Croatia, France, Germany, Great Britain, Greece, Hungary, Israel, Italy, Romania, Sicily, Slovakia, Slovenia, Spain, Switzerland, Turkey, Ukraine, Russia, Belarus (Pohl, 2010; Cook, 2019; Ostrovsky, 2019).
REMARKS. Hylecthrus rubi is a typical parasite of many Hylaeus (Hymenoptera: Colletidae) species (Medvedev, 1965; Kinzelbach, 1971 b). However, from Russia only Hylaeus annularis has been recorded as its host. In European Russia H. annularis is a widespread and common species.
description: Published as part of Ostrovsky, A. M. & Ivlev, K. S., 2024, NEW RECORDS OF STYLOPIDS (STREPSIPTERA: STYLOPIDAE) FROM THE EUROPEAN PART OF RUSSIA, pp. 26-32 in Far Eastern Entomologist 504 on pages 27-28, DOI: 10.25221/fee.504.2, http://zenodo.org/record/14658589
Mickelomyrme zebina
Creators: name: Lelej, A. S.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Mutillidae
Mickelomyrme
Mickelomyrme zebina

description: Mickelomyrme zebina (Smith, 1860)
Mutilla zebina Smith, 1860b: 115–116; ♀, holotype, "Bac[hian]" [Indonesia, Maluku Utara, Pulau Bacan] [OUMHN]; Brothers, 2022: 172, fig. 336, ♀.
Smicromyrme zebina: Mickel, 1934: 189, 204, ♀ ♂; 1935: 292; Tsuneki et al., 1993: 21, Figs 65–71, ♀ ♂.
Mickelomyrme zebina: Lelej, 2005: 45; Pagliano et al., 2020: 175; Okayasu, 2020: 54, ♂; Pagliano et al., 2020: 175; Brothers, 2022: 172, ♀.
MATERIAL EXAMINED. Indonesia: Sulawesi, Gorontalo Lombong, Bogani Nani Wartabone N.P., 31.VIII 2008, 1♀, Sk. Yamane [SKYC]; Gorontalo Prov., Mts. Tilongkabila, 100–200 m, 2.II 2010, 1♀, Sk. Yamane [SKYC]; 20 km NE Palu, 5 km W Tawaeli, 250 m., 0º43ʹ45ʺS, 119º55ʹ95ʺE, 2.III 2009, 1♀, A. Weigel [IBSS].
DISTRIBUTION. Brunei, Indonesia (Bacan, Sulawesi, Kalimantan Timur), Philippines, Malaysia (Sabah, Sarawak).
REMARKS. The distribution of M. zebina is probably limited by Wallacea.
description: Published as part of Lelej, A. S., 2024, REVIEW OF THE VELVET ANTS (HYMENOPTERA: MUTILLIDAE) OF WALLACEA WITH SPECIAL REFERENCE TO LOMBOK, INDONESIA, pp. 1-25 in Far Eastern Entomologist 504 on pages 9-10, DOI: 10.25221/fee.504.1, http://zenodo.org/record/14658603
Terebra paucincisa Bratcher 1988
Creators: name: Salvador, Andreia
name: Pickering, Joan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Terebridae
Terebra
Terebra paucincisa

description: Terebra paucincisa Bratcher, 1988
Bratcher, 1988: 413, fig. 4.
Type locality: ‘ Grand Récif South, New Caledonia, 22°37’S, 166°51’E’.
Label locality: ‘Tailevu, Fiji’.
Collector: B. Parkinson.
Presented: T. Bratcher.
Type material: 1 paratype NHMUK 1986260.
Remarks: Holotype MNHN-IM-2000-2380.
description: Published as part of Salvador, Andreia & Pickering, Joan, 2017, Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K., pp. 101-142 in Zootaxa 4250 (2) on page 129, DOI: 10.11646/zootaxa.4250.2.1, http://zenodo.org/record/450745
Green HPLC method for determination of paracetamol and ibuprofen in human plasma: applications to pharmacokinetics
Creators: name: Helmy, Sally A
name: ElBedaiwy, Heba M
name: Helmy, Soha AM
name: Alamri, Rama A
name: Alhusayni, Renad MH
name: Almashhadi, Ibtihal AY
name: Alharbi, Aryam SG
name: Alharbi, Shouq AD
name: Ahmed-Anwar, Alaa A
name: Mohamed, Mahmoud A
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Using a straightforward, sensitive and precise liquid chromatographic approach, it is now possible to concurrently measure the amounts of ibuprofen (IBU) and paracetamol (PAR) in human plasma. A µ BondapakTM C18 column (300 mm × 3.9 mm, 15–20 μm) demonstrated acceptable separation when utilizing a mobile phase of 10 mM disodium hydrogen orthophosphate solution and acetonitrile at an 80:20, v/v ratio. The elution was isocratic at room temperature and a flow rate of 1.0 milliliters per minute. The UV detector was set to monitor PAR and IS (tinidazole) for 6.5 min at 254 nm, then IBU for the next 3 min at 220 nm. PAR and IBU showed linearity across the 0.05 to 100 µg/ml concentration range. The precision of the measurements ranged from 98.5% to 105% for PAR and from 95.1% to 102.8% for IBU. The average drug recovery rate was 100% for PAR and 98.9% for IBU. This method was effectively utilized to assess samples from an actual population administered PAR and IBU (325/200 mg) for pharmacokinetic research. The technique employs green and white tools to evaluate their environmental sustainability and efficacy. The suggested strategy was implemented utilizing the Six Sigma method. A simple, sensitive and accurate liquid chromatographic method has been developed to simultaneously quantify ibuprofen (IBU) and paracetamol (PAR) in human plasma. This method was successfully applied to analyze samples from a real population given PAR and IBU (325/200 mg) for pharmacokinetic studies. The technique employs green and white tools to evaluate their environmental sustainability and efficacy. The suggested strategy was implemented utilizing high-quality tools and the Six Sigma methodology, which yielded a process capability index (Cpk) value exceeding 1.33.
MOESM2 of Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain
Creators: name: Asahchop, Eugene
name: Meziane, Oussama
name: Mamik, Manmeet
name: Chan, Wing
name: Branton, William
name: Resch, Lothar
name: M. Gill
name: Haddad, Elie
name: Guimond, Jean
name: Wainberg, Mark
name: Baker, Glen
name: Cohen, Eric
name: Power, Christopher
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 2. Â Intracellular and extracellular ARV drug concentrations inÂ differentiated human THP-1 cells that were stimulated with LPS or infected withÂ HIV-1 and treated with DRV or RAL at different concentrations for 24 hours.Â Drug concentrations were measured by HPLC-MS.
title: Sutera, Jamesbrittenia :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Plants
Sutera
New Varieties of Plants
Jamesbrittenia

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
Additional file 3: Table S2B. of Personalized treatment of women with early breast cancer: a risk-group specific cost-effectiveness analysis of adjuvant chemotherapy accounting for companion prognostic tests OncotypeDX and Adjuvant!Online
Creators: name: Jahn, Beate
name: Rochau, Ursula
name: Kurzthaler, Christina
name: Hubalek, Michael
name: Miksad, Rebecca
name: Sroczynski, Gaby
name: Paulden, Mike
name: Bundo, Marvin
name: Stenehjem, David
name: Brixner, Diana
name: Krahn, Murray
name: Siebert, Uwe
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology

description: Sensitivity Analysis of cost effectiveness of chemotherapy in subgroups with an intermediate risk according to OncotypeDX. â  Table S2Bâ   is referring to TableÂ 2b: Sensitivity Analysis of cost effectiveness of chemotherapy in subgroups with an intermediate risk according to OncotypeDX. (DOCX 18 kb)
Spitosa Espeland, Huang & Inayoshi 2024, nom. nov.
Creators: name: Huang, Si-Yao
name: Inayoshi, Yutaka
name: Espeland, Marianne
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Riodinidae
Spitosa

description: Spitosa Espeland, Huang & Inayoshi, nom. nov.
Figs. 1, 2, 7
Sospita Hewitson, 1861: 75 (junior homonym of Sospita Mulsant, 1846: 137 (Coleoptera, Coccinellidae)).
Sospitia Evans, 1927: 126 (incorrect subsequent spelling).
Type species: Taxila fylla Westwood, 1851, fixed through Art. 67.8 of the Code (ICZN 1999).
Diagnosis. Externally, Spitosa can be easily distinguished from Abisara (Figs. 5, 6, 9) and all the other riodinid genera distributed in Asia by the forewing bearing a narrow and clear transverse band in the discal zone extending from costa to tornus (sometimes with an additional paler one in the postdiscal zone) and the hindwing tail-like projection obsolete. In male genitalia, Spitosa can be distinguished from Abisara as well as Sibosia easily by the presence of the central plate and juxta, the broader valvae and the distal section of valvae rounded, while the distal section of valvae is bifurcate in Abisara and the valvae are much slender and ended in a narrow and curved distal process in Sibosia.
Etymology. The name Spitosa is an anagram of the generic name Sospita, its gender is feminine.
Species composition.
S. fylla (Westwood, 1851), comb. nov. (Figs. 1, 2, 7)
S. fylloides (Moore, 1901), comb. nov.
S. magdala (Fruhstorfer, 1904), comb. nov.
S. sobrina (Mell, 1923), comb. nov.
description: Published as part of Huang, Si-Yao, Inayoshi, Yutaka & Espeland, Marianne, 2024, Two new genus-group replacement names of Riodinidae from Asia (Lepidoptera, Papilionoidea, Riodinidae), pp. 295-300 in Zootaxa 5512 (2) on page 296, DOI: 10.11646/zootaxa.5512.2.10, http://zenodo.org/record/13848592
Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique
Creators: name: Said, Rana
name: Ghazzy, Asma
name: Shakya, Ashok K.
name: Al hunaiti, Afnan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Iron oxide nanozymes (IONzymes) have become fundamental components in various analyte detection methodologies such as colorimetric, electrochemistry, fluorescence and luminescence. Their tunability, stability and the possibility of modification, alongside their ability to mimic the catalytic properties of natural enzymes like peroxidase, render them invaluable in analytical chemistry. This review explores the diverse applications of IONzymes across analytical chemistry, with a particular highlighting on their roles in different detection techniques and their potential in biomedical and diagnostic applications. This information would be valuable for researchers and practitioners in the fields of analytical chemistry, biochemistry, biotechnology and materials science who are interested in applying IONzymes in their work. In essence, this review article on iron oxide nanozymes in analytical chemistry would serve as a valuable resource for researchers, educators and industry professionals, offering insights, guidance and inspiration for further study and application of this promising class of nanomaterials. Iron oxide nanozymes exhibit catalytic properties that simulate natural enzymes, making them valuable in analytical applications. The variety of iron oxide nanozymes is leading to their widespread use as detection tools in various fields, from biosensing to environmental monitoring. These nanozymes possess enzyme-mimicking activities, including oxidase, peroxidase and catalase-like behaviors, which make them fitting for a range of analytical applications. Iron oxide nanozymes have been successfully employed in colorimetric, electrochemical and fluorescence-based detection techniques. Their capability to catalyze reactions without the limitations of natural enzymes makes them highly stable and effective for detection in various samples. Present challenges include enhancing the selectivity and sensitivity of nanozyme-based detection systems. Future research is expected to focus on developing novel hybrid nanozymes and improving their biocompatibility for use in practical everyday life situations.
Neotrogaspidia tricarinata
Creators: name: Lelej, A. S.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Mutillidae
Neotrogaspidia
Neotrogaspidia tricarinata

description: Neotrogaspidia tricarinata (Zavattari, 1907)
Mutilla tricarinata Zavattari, 1907: 1, ♂, holotype, ♂, “ Mutilla tricarinata Zav. ” [Zavattari’s handwriting]; “ Trogaspidia tricarinata tricarinata (Zav.) B.Petersen det. [typeset] 1978 [Petersen’s handwriting]”; “ Holotype [typeset] tricarinata [Petersen’s handwriting]” [MRSN]; Brothers, 2022: 156, fig. 305, ♂.
Trogaspidia tricarinata: Lelej, 2005: 104, ♂; Pagliano et al., 2020: 292.
Neotrogaspidia tricarinata: Brothers, 2022: 156, ♂; Okayasu, 2023: 4, ♂.
MATERIAL EXAMINED. Two males [ZIN] with wrong labels "Владивосток", "Проф[ессор] Таренецкий" [=Vladivostok, "Professor Tarenetsky"] have been identified by late B. Petersen in 1982 as Trogaspidia tricarinata (Zavattari, 1907).
DISTRIBUTION. Indonesia (Aru or Kei).
REMARKS. According to B. Petersen, the type locality of this species should be Kepulauan Aru (06°09'S, 134°30'E) or Kepulauan Kei (05°45'S, 132°43'E), Maluku, Indonesia (Brothers, 2022).
description: Published as part of Lelej, A. S., 2024, REVIEW OF THE VELVET ANTS (HYMENOPTERA: MUTILLIDAE) OF WALLACEA WITH SPECIAL REFERENCE TO LOMBOK, INDONESIA, pp. 1-25 in Far Eastern Entomologist 504 on page 17, DOI: 10.25221/fee.504.1, http://zenodo.org/record/14658603
Additional file 2: of A set of systematic reviews to help reduce inappropriate prescribing to older people: study protocol
Creators: name: Martinez, Yolanda
name: Renom-Guiteras, Anna
name: Reeves, David
name: R. Erandie Ediriweera De Silva
name: Aneez Esmail
name: Kunnamo, Ilkka
name: Rieckert, Anja
name: Sommerauer, Christina
name: SĂśnnichsen, Andreas
Publisher: name: Figshare
Year: 2017
Subjects: Medicine
Developmental Biology
Science Policy

description: Standard operating procedure. (DOCX 77Â kb)
Sibosia Espeland, Huang & Inayoshi 2024, nom. nov.
Creators: name: Huang, Si-Yao
name: Inayoshi, Yutaka
name: Espeland, Marianne
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Riodinidae
Sibosia

description: Sibosia Espeland, Huang & Inayoshi, nom. nov.
Figs. 3, 4, 8
Sosibia Fruhstorfer, 1914: 75 (junior homonym of Sosibia Stål, 1875: 42 (Phasmatodea, Lonchodidae)).
Type species: Taxila burnii Nicéville, 1895, fixed through Art. 67.8 of the Code (ICZN 1999).
Diagnosis. Externally, Sibosia can be easily distinguished from Abisara (Figs. 5, 6, 9) by the discal and postdiscal bands on the forewing underside represented by short and discontinuous white short lines or dots and the absence of the tail-like projection on the hindwing, while in Abisara those bands on the forewing underside are narrow and continuous. In male genitalia, Sibosia can be distinguished from Abisara by lacking the external process on valvae. In general appearance Sibosia is also reminiscent of Taxila but can be readily distinguished from the latter by the ill-developed black spots proximal to the white spots on the forewing underside and the valvae without the inner basal process in the male genitalia.
Etymology. The name Sibosia is an anagram of the generic name Sosibia, its gender is feminine.
Species composition.
S. burnii (Nicéville, 1895), comb. nov.
description: Published as part of Huang, Si-Yao, Inayoshi, Yutaka & Espeland, Marianne, 2024, Two new genus-group replacement names of Riodinidae from Asia (Lepidoptera, Papilionoidea, Riodinidae), pp. 295-300 in Zootaxa 5512 (2) on pages 296-297, DOI: 10.11646/zootaxa.5512.2.10, http://zenodo.org/record/13848592
Terebra (Myurella) paucistriata Smith 1873
Creators: name: Salvador, Andreia
name: Pickering, Joan
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Terebridae
Terebra
Terebra paucistriata

description: Terebra (Myurella) paucistriata Smith, 1873
Smith, 1873: 269.
Type locality: ‘Ovalau, Fiji Islands, 5 fathoms (J. Macgillivray)’.
Label locality: ‘5 fms. Ovalau, Fiji Is.’.
Collector: J. Macgillivray.
Presented: The Admiralty.
Type material: Lectotype NHMUK 1856.11.3.17. Indirect lectotype selection by inference of holotype (Cernohorsky, 1969: 218).
description: Published as part of Salvador, Andreia & Pickering, Joan, 2017, Type catalogue of Terebridae (Mollusca, Gastropoda, Conoidea) in the Natural History Museum, London, U. K., pp. 101-142 in Zootaxa 4250 (2) on page 129, DOI: 10.11646/zootaxa.4250.2.1, http://zenodo.org/record/450745
Green HPLC method for determination of paracetamol and ibuprofen in human plasma: applications to pharmacokinetics
Creators: name: Helmy, Sally A
name: ElBedaiwy, Heba M
name: Helmy, Soha AM
name: Alamri, Rama A
name: Alhusayni, Renad MH
name: Almashhadi, Ibtihal AY
name: Alharbi, Aryam SG
name: Alharbi, Shouq AD
name: Ahmed-Anwar, Alaa A
name: Mohamed, Mahmoud A
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Using a straightforward, sensitive and precise liquid chromatographic approach, it is now possible to concurrently measure the amounts of ibuprofen (IBU) and paracetamol (PAR) in human plasma. A µ BondapakTM C18 column (300 mm × 3.9 mm, 15–20 μm) demonstrated acceptable separation when utilizing a mobile phase of 10 mM disodium hydrogen orthophosphate solution and acetonitrile at an 80:20, v/v ratio. The elution was isocratic at room temperature and a flow rate of 1.0 milliliters per minute. The UV detector was set to monitor PAR and IS (tinidazole) for 6.5 min at 254 nm, then IBU for the next 3 min at 220 nm. PAR and IBU showed linearity across the 0.05 to 100 µg/ml concentration range. The precision of the measurements ranged from 98.5% to 105% for PAR and from 95.1% to 102.8% for IBU. The average drug recovery rate was 100% for PAR and 98.9% for IBU. This method was effectively utilized to assess samples from an actual population administered PAR and IBU (325/200 mg) for pharmacokinetic research. The technique employs green and white tools to evaluate their environmental sustainability and efficacy. The suggested strategy was implemented utilizing the Six Sigma method. A simple, sensitive and accurate liquid chromatographic method has been developed to simultaneously quantify ibuprofen (IBU) and paracetamol (PAR) in human plasma. This method was successfully applied to analyze samples from a real population given PAR and IBU (325/200 mg) for pharmacokinetic studies. The technique employs green and white tools to evaluate their environmental sustainability and efficacy. The suggested strategy was implemented utilizing high-quality tools and the Six Sigma methodology, which yielded a process capability index (Cpk) value exceeding 1.33.