Additional file 1 of Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid receptor-dependent activation of EGFR
Creators: name: Xiao, Kai
name: Zheng, Qinghong
name: Bao, Lei
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Additional file 1: Table S1. Average and standard derivation (SD) value of migration in fentanyl-treated ovarian cancer cells. Results were presented as relative to control. Control was set as 1 in three independent experiments, thus SD of control is 0. Table S2. Average and standard derivation (SD) value of proliferation in fentanyl-treated ovarian cancer cells. Results were presented as relative to control. Control was set as 1 in three independent experiments, thus SD of control is 0. Table S3. Average and standard derivation (SD) value of apoptosis in fentanyl-treated ovarian cancer cells. Results were presented as relative to control. Control was set as 1 in three independent experiments, thus SD of control is 0. Table S4. Average and standard derivation (SD) value of apoptosis in drug-treated ovarian cancer cells. Results were presented as relative to control. Control was set as 1 in three independent experiments, thus SD of control is 0. Table S5. Average and standard derivation (SD) value of WB density in fentanyl-treated ovarian cancer cells. Results were presented as relative to control. Control was set as 1 in three independent experiments, thus SD of control is 0. Table S6. Average and standard derivation (SD) value of WB density in fentanyl-treated ovarian cancer cells. Results were presented as relative to control. Control was set as 1 in three independent experiments, thus SD of control is 0. Table S7. Average and standard derivation (SD) value of migration in siEGFR-treated ovarian cancer cells. Results were presented as relative to control (si-Ctrl). Control (si-Ctrl) was set as 1 in three independent experiments, thus SD of control is 0. Table S8. Average and standard derivation (SD) value of proliferation in siEGFR-treated ovarian cancer cells. Results were presented as relative to control (si-Ctrl). Control (si-Ctrl) was set as 1 in three independent experiments, thus SD of control is 0. Table S9. Average and standard derivation (SD) value of migration in drug-treated ovarian cancer cells. Results were presented as relative to control (DMSO). Control (DMSO) was set as 1 in three independent experiments, thus SD of control is 0. Table S10. Average and standard derivation (SD) value of proliferation in drug-treated ovarian cancer cells. Results were presented as relative to control (DMSO). Control (DMSO) was set as 1 in three independent experiments, thus SD of control is 0. Fig. S1. Uncropped western blot images for Fig. 4A: p-PDGFR-β, PDGFR-β, p-EGFR, EGFR, p-ERK, ERK, p-90RSK, 90RSK, p-Akt, Akt, Vimentin, Snail, Slug, Claudin-1 and β-actin. Three independent experiments were included. MW: molecular weight; WB: western blotting. The blots were cut prior to hybridisation with antibodies during blotting. Fig. S2. Uncropped western blot images for Fig. 5A. EGFR and β-actin. Three independent experiments were included. MW: molecular weight; WB: western blotting. The blots were cut prior to hybridisation with antibodies during blotting. Fig. S3. Uncropped western blot images for Fig. 5D. p-EGFR, EGFR and β-actin. Three independent experiments were included. MW: molecular weight; WB: western blotting. The blots were cut prior to hybridisation with antibodies during blotting.