cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Bayesian Markov-switching correlation model for contagion analysis on exchange rate markets
Creators: name: Casarin, Roberto
name: Sartore, Domenico
name: Tronzano, Marco
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: This paper develops a new Markov-switching vector autoregressive model (VAR) with stochastic correlation for contagion analysis on financial markets. The correlation and the log-volatility dynamics are driven by two independent Markov chains, thus allowing for different effects such as volatility spill-overs and correlation shifts with various degrees of intensity. We outline a suitable Bayesian inference procedure based on Markov Chain Monte Carlo algorithms. We then apply the model to some major and Asian-Pacific cross rates against the US Dollar and find strong evidence supporting the existence of contagion effects and correlation drops during crises, closely in line with the stylized facts outlined in the contagion literature. A comparison of this model with its closest competitors, such as a time-varying parameter VAR, reveals that our model has a better predictive ability.
Health Prevention Interventions for Adults in the Community: A Scoping Review of Intervention Characteristics
Creators: name: Molitor, Whitney Lucas
name: Naber, Allison
name: Duncan, Karlee
name: Wall, Jenna
name: Wookey, Hunter
name: Steineke, Tanner
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: This scoping review was designed to determine which adults receive preventative health interventions, the types of interventions for modifiable risk factors, the health professionals, including occupational therapy practitioners providing these interventions, and where they are delivered to adults in the community. The databases searched were PubMed, Ageline, and CINAHL and included research meeting the inclusion criteria and published between 2016–2021. All included studies addressed health prevention. 5,399 articles were screened with 83 of these included in the final review. Older adults, White and Black individuals, and females were the most prevalent individuals and groups to receive health prevention interventions and occupational therapy professionals were involved in 5% of the reviewed studies. As there is a need for preventative health interventions to help reduce negative health outcomes and occupational therapy professionals have important skills in health prevention this study illustrates the types of health prevention provided to adults receiving intervention in the community and points to areas of opportunity for occupational therapy professionals.
Efficacy Studies of Home-Based Occupational Therapy Services Following Stroke: A Scoping Review
Creators: name: Zachry, Anne H.
name: Williams, Lee
name: Chen, Ming
name: Surbhi, Satya
name: Bailey, Jim
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: The aim of this scoping review was to review and assess recent studies on the efficacy of home-based occupational therapy interventions for adults post-stroke. The number of efficacy studies is limited. The few studies available suggest that occupational therapy delivered in home settings may improve outcomes for stroke patients. There is also limited use of occupation-based assessments, interventions, and outcome measures in studies addressing home-based occupational therapy. Methodologies should be improved to include contexts, caregiver training, and self-efficacy. Further high-quality studies are needed on the efficacy home-based occupational therapy services.
Can Occupation-Based Interventions for People Living with Dementia and Their Spousal Caregivers Support Positive Aspects of Caregiving? A Scoping Review
Creators: name: Ramachandran, Meena
name: Chin, Julia
name: Cheung, Vincent
name: Cope, Jenna
name: Belchior, Patricia
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: This scoping review aimed to explore the characteristics and outcomes of occupation-based interventions for people living with dementia and their spousal caregivers relating to positive aspects of caregiving. A conceptualization of positive aspects of caregiving was developed based on the existing literature encompassing three domains – quality of the caregiver/care receiver relationship, meaning of the caregiver’s role in daily life, and caregiver’s feeling of accomplishment. Arksey and O’Malley’s guidelines were used and four databases were searched to identify studies discussing occupation-based interventions involving spousal caregivers and persons living with dementia in the community that addressed at least one of three domains of positive aspects of caregiving identified in our conceptualization. After screening 1,560 articles, 18 articles were included for analysis. Three types of interventions were identified (i.e. music therapy, reminiscence therapy and a tailored activity program) involving three components contributing to positive aspects of caregiving: socializing outside the dyad, producing tangible end products, and education for the caregiver or dyad. Findings indicate that occupation-based interventions can support positive experiences for the dyad by improving the quality of the dyadic relationship and caregivers’ feelings of accomplishment.
title: 02_0462
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
PEG-400 as an Efficient and Recyclable Reaction Medium for the Synthesis of 2-Aryl-2-methyl-4,5-diphenyl-2,3-dihydro-2H-imidazoles
Creators: name: Nageshwar Rao Penumati
name: Lingayya Rajaka
name: Nagaiah Kommu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry

description: A productive natural amicable philosophy has been produced for the synthesis of 2-aryl-2-methyl-4,5-diphenyl-2,3-dihydro-2H-imidazoles in great yields under catalyst free-conditions utilizing polyethylene glycol (PEG-400) as green reaction medium. The highlights of this new method are shorter reaction times, high yields, room temperature, non-toxic, inexpensive, and recyclability of the PEG-400.
STUDI PENGGUNAAN MATERIAL RAMAH LINGKUNGAN DALAM KONSTRUKSI BANGUNAN
Creators: name: Refli, Refli
Publisher: name: Zenodo
Year: 2024

description: Kerusakan lingkungan dan pemanasan global merupakan fenomena yang telah terjadi di dunia. Perkembangan proyek konstruksi dianggap memiliki peran terhadap terjadinya fenomena tersebut. Maka dibutuhkan suatu konsep Pembangunan yang memperhatikan kondisi lingkungan sekitar atau yang sering di sebut sebagai green building salah satunya yaitu penerapan kategori green construction pada pelaksanaan konstruksi.
Biomimetic Epoxidation in Aqueous Media Catalyzed by Cyclic Dipeptides
Creators: name: Bérubé, Christopher
name: Voyer, Normand
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: We have developed a practical epoxidation of electron-deficient enones in aqueous media using cyclic dipeptides as bio-inspired green catalyst . Optimizing the reaction conditions in a triphasic system led to efficient conditions providing epoxides with good enantioselectivities. Depending on the catalyst substituent chirality, both enantiomers are obtained. The cyclic rigidity impacts significantly the enantioselectivity.
Synthesis of α-trifluoromethyl-β-keto phosphonates by electrophilic trifluoromethylation with Togni reagent
Creators: name: Fu, Wen-Zhi
name: Yangen Huang
name: Xu, Xiu-Hua
name: Qing, Feng-Ling
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: A new synthetic method of trifluoromethylated phosphonates was developed via electrophilic trifluoromethylation with Togni reagent. A variety of β-keto phosphonates were converted into the corresponding α-trifluoromethyl-β-keto phosphonates in moderate to good yields. This protocol could also be extended to other fluoroalkylation reactions, such as pentafluoroethylation.
[ARTICLE] Relativity of π as a Function of the Rotation of N-Sided Unit Polygons [Canadian Journal of Mathematics Research / 2022]
Creators: name: Teia, Luis
Publisher: name: figshare
Year: 2022
Subjects: subject: 10101 Algebra and Number Theory
subject: FOS: Mathematics
subject: Geometry
subject: 10199 Pure Mathematics not elsewhere classified
subject: 10599 Mathematical Physics not elsewhere classified

description: This article presents a new way to determine the value of π, using as an approach the area formed by the interference pattern of several rotating unit squares. The same approach is then applied to other N-sided unit polygons (i.e., triangles, pentagons and hexagons) to investigate how they affect this proportionality between circularity and linearity to a degree other than orthogonal (i.e., when the system axes do not form a right-angle, expressible in the new method as an approach that uses squares). Applied examples involving the Earth’s size and an orbiting satellite constellation are given.

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Copyright for this article is retained by the author(s), with first publication rights granted to the journal. This is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
Macular Ganglion Cell Layer and Peripapillary Retinal Nerve Fibre Layer Thickness in Patients with Unilateral Posterior Cerebral Artery Ischaemic Lesion: An Optical Coherence Tomography Study
Creators: name: Anjos, Rita
name: Vieira, Luisa
name: Costa, Livio
name: Vicente, André
name: Santos, Arnaldo
name: Alves, Nuno
name: Amado, Duarte
name: Ferreira, Joana
name: Cunha, João Paulo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: The purpose of this study is to evaluate the macular ganglion cell layer (GCL) and peripapillary retinal nerve fibre layer (RNFL) thickness in patients with unilateral posterior cerebral artery (PCA) ischaemic lesions using spectral-domain optical coherence tomography (SD-OCT). A prospective, case-control study of patients with unilateral PCA lesion was conducted in the neuro-ophthalmology clinic of Centro Hospitalar Lisboa Central. Macular and peripapillary SD-OCT scans were performed in both eyes of each patient. Twelve patients with PCA lesions (stroke group) and 12 healthy normal controls were included in this study. Peripapillary RNFL comparison between both eyes of the same subject in the stroke group found a thinning in the superior-temporal (p = 0.008) and inferior-temporal (p = 0.023) sectors of the ipsilateral eye and nasal sector (p = 0.003) of the contralateral eye. Macular GCL thickness comparison showed a reduction temporally in the ipsilateral eye (p = 0.004) and nasally in the contralateral eye (p = 0.002). Peripapillary RNFL thickness was significantly reduced in both eyes of patients with PCA compared with controls, affecting all sectors in the contralateral eye and predominantly temporal sectors in the ipsilateral eye. A statistically significant decrease in macular GCL thickness was found in both hemiretinas of both eyes of stroke patients when compared with controls (p < 0.05). This study shows that TRD may play a role in the physiopathology of lesions of the posterior visual pathway.
Analisis riview - REPRESENTASI TERAPI KOGNITIF PERILAKU (COGNITIVE BEHAVIOURAL THERAPY) DALAM DUNIA MIMPI SERIAL ANIMASI WONDER EGG PRIORITY
Creators: name: Altauziri, Galih Yusuf
Publisher: name: Zenodo
Year: 2022
Subjects: Psikologi
Trauma
Mental
Animasi
Trapi
Repsentasi

description: Analisis riview - REPRESENTASI TERAPI KOGNITIF PERILAKU (COGNITIVE BEHAVIOURAL THERAPY) DALAM DUNIA MIMPI SERIAL ANIMASI WONDER EGG PRIORITY
Vetus Hydreuma, praesidium no. 5 plan
Creators: name: Wilkinson, J. G.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Vetus Hydreuma, praesidium no. 5 (site 2e) (drawing by J.G. Wilkinson, MS. Wilkinson dep.a.15.49, courtesy Bodleian Library, Oxford)
Synthesis of α-Trifluoromethyl-β-keto Phosphonates by Electrophilic Trifluoromethylation with Togni Reagent
Creators: name: Fu, Wen-Zhi
name: Yangen Huang
name: Xu, Xiu-Hua
name: Qing, Feng-Ling
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: A new synthetic method of trifluoromethylated phosphonates was developed via electrophilic trifluoromethylation with Togni reagent. A variety of β-keto phosphonates were converted into the corresponding α-trifluoromethyl-β-keto phosphonates in moderate to good yields. This protocol could also be extended to other fluoroalkylation reactions, such as pentafluoroethylation.
Flavobacterium psychrophilum Infections in Salmonid Broodstock and Hatchery-Propagated Stocks of the Great Lakes Basin
Creators: name: Vliet, Danielle Van
name: Loch, Thomas P.
name: Faisal, Mohamed
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Bacterial coldwater disease (BCWD), caused by Flavobacterium psychrophilum, threatens wild and propagated salmonids worldwide and leads to substantial economic losses. In addition to being horizontally transmitted, F. psychrophilum can be passed from infected parents to their progeny, furthering the negative impacts of this pathogen. In Michigan, both feral and captive salmonid broodstocks are the gamete sources used in fishery propagation efforts. A 5-year study was initiated to follow the prevalence of systemic F. psychrophilum infections in feral broodstocks of four species (steelhead Oncorhynchus mykiss [potadromous Rainbow Trout]; Coho Salmon O. kisutch; Chinook Salmon O. tshawytscha; and Atlantic Salmon Salmo salar) residing in three Great Lakes watersheds. Additionally, captive broodstocks of four species (Rainbow Trout, Brown Trout Salmo trutta, Lake Trout Salvelinus namaycush, and Brook Trout Salvelinus fontinalis) maintained at two facilities were assessed for the presence of F. psychrophilum. The resultant offspring from each broodstock population were sampled for F. psychrophilum infections multiple times throughout hatchery residency. Using selective flavobacterial culture and PCR confirmation, F. psychrophilum was detected in all broodstocks except the captive Lake Trout and Brook Trout. Logistic regression analysis demonstrated that among the infected feral broodstocks, Chinook Salmon from the Lake Michigan watershed had the highest prevalence of systemic F. psychrophilum infection (mean = 63.2%). Among the captive broodstocks, the Gilchrist Creek strain of Brown Trout had the highest infection prevalence (mean = 5%). Collectively, the captive broodstocks were found to have significantly lower infection prevalence than the feral broodstocks. Despite the high prevalence of systemic F. psychrophilum infections in many broodstock populations, the bacterium was rarely detected in their progeny during hatchery rearing. However, heavy losses associated with clinical BCWD outbreaks did occur. Collectively, our results reinforce that BCWD continues to threaten Great Lakes basin salmonids. Received April 6, 2015; accepted August 25, 2015
Streptomyces-derived actinomycin D inhibits biofilm formation by Staphylococcus aureus and its hemolytic activity
Creators: name: Lee, Jin-Hyung
name: Yong-Guy Kim
name: Kayeon Lee
name: Kim, Chang-Jin
name: Park, Dong-Jin
name: Yoonjung Ju
name: Jae-Chan Lee
name: Wood, Thomas K.
name: Jintae Lee
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Staphylococcus aureus is a versatile human pathogen that produces diverse virulence factors, and its biofilm cells are difficult to eradicate due to their inherent ability to tolerate antibiotics. The anti-biofilm activities of the spent media of 252 diverse endophytic microorganisms were investigated using three S. aureus strains. An attempt was made to identify anti-biofilm compounds in active spent media and to assess their anti-hemolytic activities and hydrophobicities in order to investigate action mechanisms. Unlike other antibiotics, actinomycin D (0.5 μg ml−1) from Streptomyces parvulus significantly inhibited biofilm formation by all three S. aureus strains. Actinomycin D inhibited slime production in S. aureus and it inhibited hemolysis by S. aureus and caused S. aureus cells to become less hydrophobic, thus supporting its anti-biofilm effect. In addition, surface coatings containing actinomycin D prevented S. aureus biofilm formation on glass surfaces. Given these results, FDA-approved actinomycin D warrants further attention as a potential antivirulence agent against S. aureus infections.
Towards the origin of effective An(III)/Ln(III) separation by tridentate N-donor ligands: a theoretical study on atomic charges and polarisabilities for Cm(III)/Gd(III) separation
Creators: name: Trumm, Michael
name: Schimmelpfennig, Bernd
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Soft N-donor ligand have shown to separate An(III) from Ln(III). The origin of the selectivity has not been entirely identified, and similar ligands show very different separation qualities. In this study we present a theoretical investigation of several relevant N-donor ligands in terms of atomic charges and polarisabilities obtained from an atoms in molecules approach. These allow new insights into the bonds between the ligands’ nitrogen atoms and the metal cation and explain a major part of the selectivity towards actinide ions. We deduct the superiority of 2,6-bis(1,2,4-triazine-3-yl)pyridines in separation quality compared to similar ligands for the Cm(III)/Gd(III) separation. Furthermore, improvements of existing ligands are developed that allow not only a direct experimental confirmation but also a systematic experimental study of the interactions and their influence on the selectivity.
Influence of carbon steel grade on the initial attachment of bacteria and microbiologically influenced corrosion
Creators: name: M.A. Javed
name: W.C. Neil
name: P.R. Stoddart
name: S.A. Wade
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: The influence of the composition and microstructure of different carbon steel grades on the initial attachment (≤ 60 min) of Escherichia coli and subsequent longer term (28 days) corrosion was investigated. The initial bacterial attachment increased with time on all grades of carbon steel. However, the rate and magnitude of bacterial attachment varied on the different steel grades and was significantly less on the steels with a higher pearlite phase content. The observed variations in the number of bacterial cells attached across different steel grades were significantly reduced by applying a fixed potential to the steel samples. Longer term immersion studies showed similar levels of biofilm formation on the surface of the different grades of carbon steel. The measured corrosion rates were significantly higher in biotic conditions compared to abiotic conditions and were found to be positively correlated with the pearlite phase content of the different grades of carbon steel coupons.
Guaranteeing performance based on time-stability for energy-efficient data centers
Creators: name: Soongeol Kwon
name: Natarajan Gautam
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: We consider a system of multiple parallel single-server queues where servers are heterogeneous with resources of different capacities and can be powered on or off while running at different speeds when they are powered on. In addition, we assume that application requests are heterogeneous with different workload distributions and resource requirements and the arrival, rates of request are time-varying. Managing such a heterogeneous, transient, and non-stationary system is a tremendous challenge. We take an unconventional approach, in that we force the queue lengths in each powered-on server to be time-stable (i.e., stationary). It allows the operators to guarantee performance and effectively monitor the system. We formulate a mixed-integer program to minimize energy costs while satisfying time-stability. Simulation results show that our suggested approach can stabilize queue length distributions and provide probabilistic performance guarantees on waiting times.
RNA-template dependent de novo telomere addition
Creators: name: Fuhrmann, Gloria
name: Jönsson, Franziska
name: Weil, Patrick Philipp
name: Postberg, Jan
name: Lipps, Hans J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: De novo addition of telomeric sequences can occur at broken chromosomes and must be well controlled, which is essential during programmed DNA reorganization processes. In ciliated protozoa an extreme form of DNA-reorganization is observed during macronuclear differentiation after sexual reproduction leading to the elimination of specific parts of the germline genome. Regulating these processes involves small noncoding RNAs, but in addition DNA-reordering, excision and amplification require RNA templates deriving from the parental macronucleus. We show that these putative RNA templates can carry telomeric repeats. Microinjection of RNA templates carrying modified telomeres into the developing macronucleus leads to modified telomeres in vegetative cells, providing strong evidence, that de novo addition of telomeres depends on a telomere-containing transcript from the parental macronucleus.
Flavobacterium psychrophilum Infections in Salmonid Broodstock and Hatchery-Propagated Stocks of the Great Lakes Basin
Creators: name: Vliet, Danielle Van
name: Loch, Thomas P.
name: Faisal, Mohamed
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Bacterial coldwater disease (BCWD), caused by Flavobacterium psychrophilum, threatens wild and propagated salmonids worldwide and leads to substantial economic losses. In addition to being horizontally transmitted, F. psychrophilum can be passed from infected parents to their progeny, furthering the negative impacts of this pathogen. In Michigan, both feral and captive salmonid broodstocks are the gamete sources used in fishery propagation efforts. A 5-year study was initiated to follow the prevalence of systemic F. psychrophilum infections in feral broodstocks of four species (steelhead Oncorhynchus mykiss [potadromous Rainbow Trout]; Coho Salmon O. kisutch; Chinook Salmon O. tshawytscha; and Atlantic Salmon Salmo salar) residing in three Great Lakes watersheds. Additionally, captive broodstocks of four species (Rainbow Trout, Brown Trout Salmo trutta, Lake Trout Salvelinus namaycush, and Brook Trout Salvelinus fontinalis) maintained at two facilities were assessed for the presence of F. psychrophilum. The resultant offspring from each broodstock population were sampled for F. psychrophilum infections multiple times throughout hatchery residency. Using selective flavobacterial culture and PCR confirmation, F. psychrophilum was detected in all broodstocks except the captive Lake Trout and Brook Trout. Logistic regression analysis demonstrated that among the infected feral broodstocks, Chinook Salmon from the Lake Michigan watershed had the highest prevalence of systemic F. psychrophilum infection (mean = 63.2%). Among the captive broodstocks, the Gilchrist Creek strain of Brown Trout had the highest infection prevalence (mean = 5%). Collectively, the captive broodstocks were found to have significantly lower infection prevalence than the feral broodstocks. Despite the high prevalence of systemic F. psychrophilum infections in many broodstock populations, the bacterium was rarely detected in their progeny during hatchery rearing. However, heavy losses associated with clinical BCWD outbreaks did occur. Collectively, our results reinforce that BCWD continues to threaten Great Lakes basin salmonids. Received April 6, 2015; accepted August 25, 2015
Editorial
Creators: name: Odrig, Verena
name: Vollbrecht, Ralf
Publisher: name: Medienwelten – Zeitschrift für Medienpädagogik
Year: 2020

description: Unter den Anglizismen des Jahres 2016 schaffte es „Fake News“ noch vor den zweit- und drittplatzierten Wörtern „Dark Net“ und „Hate Speech“ zum Publikumsliebling und wurde auch von der Jury der „Aktion Anglizismen des Jahres“ 2016 auf den ersten Platz gewählt (http://www.anglizismusdesjahres.de). In seiner Laudatio weist Anatol Stefanowitsch darauf hin, dass das Wort Fake News schon im 19. Jahrhundert in ähnlicher Bedeutung wie heute verwendet wurde im Sinne einer frei erfundenen Nachricht, die politische Gegner ungünstig darstellt und von den Lesern – ist hier noch nicht die Rede – positiv aufgenommen wird, weil sie deren Weltbild bestätigt. Die früheste Verwendung datiert er auf 1894 in der Zeitschrift American Historical Register. (http://www.sprach-log.de/2017/01/31/laudatio-zum-anglizismus-des-jahres-2016-fake-news/).
description: Medienwelten – Zeitschrift für Medienpädagogik, Nr. 11 (2020): Fake News
"Kampf um den Status der Wahrheit"
Creators: name: Odrig, Verena
Publisher: name: Medienwelten – Zeitschrift für Medienpädagogik
Year: 2020

description: »Fake News« hat sich in den vergangenen Jahren als Kampfbegriff in den deutschen Printmedien etabliert. Aus medienpädagogischer Sicht steht dabei im Fokus, mit Begriffen wie diesem kundig und kritisch umgehen zu können. Mit Hilfe einer theoretischen Grundierung zum Thema »Wahrheit« mit Fokus auf die postmodernen Deutungen u. a. des französischen Philosophen Michel Foucault sowie dem Versuch einer griffigen Definition von »Fake News«, wird die Verwendung des Begriffs in der ZEIT und der Frankfurter Allgemeinen Zeitung im Jahr 2018 im Rahmen einer Diskursanalyse nach dem Modell Siegfried Jägers untersucht und die gesellschaftlichen Folgen thematisiert.
description: Medienwelten – Zeitschrift für Medienpädagogik, Nr. 11 (2020): Fake News
Guaranteeing Performance based on Time-stability for Energy-efficient Data Centers
Creators: name: Soongeol Kwon
name: Natarajan Gautam
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: We consider a system of multiple parallel single server queues where servers are heterogeneous with resources of different capacities, and could be powered on or off while running at different speeds when they are powered on. In addition we assume that application requests are heterogeneous with different workload distributions and resource requirements, and the arrival rates of request are time-varying. Managing such a heterogeneous, transient and non-stationary system is a tremendous challenge. We take an unconventional approach in that we force the queue lengths in each powered-on server to be time-stable (i.e. stationary). It allows the operators to guarantee performance and effectively monitor the system. We formulate a mixed integer program to minimize energy costs while satisfying time-stability. Simulation results show that our suggested approach can stabilize queue length distributions and provide probabilistic performance guarantees on waiting times. “Supplementary materials are available for this article. Go to the publisher's online edition of IIE Transaction, datasets, additional tables, detailed proofs, etc.”
All-in-one Xylella detection and identification: A nanopore sequencing-compatible conventional PCR
Creators: name: Wong-Bajracharya, Johanna
name: Webster, John
name: Rigano, Luciano A
name: Kant, Pragya
name: Englezou, Anna
name: Snijders, Fridtjof
name: Roach, Rebecca
name: Wang, Cuiping
name: Kehoe, Monica
name: Mann, Rachel
name: Constable, Fiona
name: Chapman, Toni A
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 310805
subject: Plant pathology
classificationCode: 3004
subject: Crop and pasture production
classificationCode: 3108
subject: Plant biology
classificationCode: 3107
subject: Microbiology

description: Xylella fastidiosa is a plant-pathogenic bacterium that poses a serious threat to the production of economically important plant species including grapes, almonds, olives and a broad range of amenity plants, causing significant economic losses worldwide. While multiple molecular detection assays have been developed for X. fastidiosa, there is a lack of molecular tools available for detection and differentiation of the closely related pear pathogen, Xylella taiwanensis. In this study, we present a novel conventional PCR assay with primers that can amplify both Xylella species. The amplified product could be sequenced and used for discrimination between the two species and the subspecies within the fastidiosa species. This PCR assay was designed using a genome-informed approach to target the ComEC/Rec2 gene of both Xylella species, ensuring a higher specificity than other previously developed PCR assays. A test performance study across five national plant diagnostic laboratories in Australia and New Zealand demonstrated this assay's high sensitivity and specificity to all known species and subspecies within the Xylella genus. This PCR assay can be used for Xylella identification at the species and subspecies level and is compatible with Sanger sequencing and nanopore sequencing for rapid turnaround time. The newly developed conventional PCR assay presented here offers rapid detection and accurate identification of both Xylella species from plant, insect vector or bacterial samples, enabling timely implementation of biosecurity measures or disease management responses.
RNA-template dependentde novotelomere addition
Creators: name: Fuhrmann, Gloria
name: Jönsson, Franziska
name: Weil, Patrick Philipp
name: Postberg, Jan
name: Lipps, Hans J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: De novo addition of telomeric sequences can occur at broken chromosomes and must be well controlled, which is essential during programmed DNA reorganization processes. In ciliated protozoa an extreme form of DNA-reorganization is observed during macronuclear differentiation after sexual reproduction leading to the elimination of specific parts of the germline genome. Regulating these processes involves small noncoding RNAs, but in addition DNA-reordering, excision and amplification require RNA templates deriving from the parental macronucleus. We show that these putative RNA templates can carry telomeric repeats. Microinjection of RNA templates carrying modified telomeres into the developing macronucleus leads to modified telomeres in vegetative cells, providing strong evidence, that de novo addition of telomeres depends on a telomere-containing transcript from the parental macronucleus.
Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi
Creators: name: Watanabe, Colin
name: Trinna L. Cuellar
name: Haley, Benjamin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Incorporating miRNA-like features into vector-based hairpin scaffolds has been shown to augment small RNA processing and RNAi efficiency. Therefore, defining an optimal, native hairpin context may obviate a need for hairpin-specific targeting design schemes, which confound the movement of functional siRNAs into shRNA/artificial miRNA backbones, or large-scale screens to identify efficacious sequences. Thus, we used quantitative cell-based assays to compare separate third generation artificial miRNA systems, miR-E (based on miR-30a) and miR-3G (based on miR-16-2 and first described in this study) to widely-adopted, first and second generation formats in both Pol-II and Pol-III expression vector contexts. Despite their unique structures and strandedness, and in contrast to first and second-generation RNAi triggers, the third generation formats operated with remarkable similarity to one another, and strong silencing was observed with a significant fraction of the evaluated target sequences within either promoter context. By pairing an established siRNA design algorithm with the third generation vectors we could readily identify targeting sequences that matched or exceeded the potency of those discovered through large-scale sensor-based assays. We find that third generation hairpin systems enable the maximal level of siRNA function, likely through enhanced processing and accumulation of precisely-defined guide RNAs. Therefore, we predict future gains in RNAi potency will come from improved hairpin expression and identification of optimal siRNA-intrinsic silencing properties rather than further modification of these scaffolds. Consequently, third generation systems should be the primary format for vector-based RNAi studies; miR-3G is advantageous due to its small expression cassette and simplified, cost-efficient cloning scheme.
Additional file 1 of Individual consistency in migration strategies of a tropical seabird, the Round Island petrel
Creators: name: Franklin, Kirsty A.
name: Norris, Ken
name: Gill, Jennifer A.
name: Ratcliffe, Norman
name: Bonnet-Lebrun, Anne-Sophie
name: Butler, Simon J.
name: Cole, Nik C.
name: Jones, Carl G.
name: Lisovski, Simeon
name: Ruhomaun, Kevin
name: Tatayah, Vikash
name: Nicoll, Malcolm A. C.
Publisher: name: figshare
Year: 2022
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1. Table S1: Details of all geolocator deployments and recoveries on adult Round Island petrels from 2009 to 2019, and number of complete migrations which took place in each petrel year for the 62 petrels with repeat migrations. Table S2: Results of ANOVA tests for generalised linear model selection for the similarity of petrel migrations within- and between- individuals, using a) the earth mover’s distance (EMD) ‘effort’ values, and b) Bhattacharyya’s affinity (BA), and the spatiotemporal similarity of within-individual petrel migrations when split into c) six equal size stages, and d) 30-day periods, both using EMD. Significant effects (p
Centers of motion associated with EF-Tu binding to the ribosome
Creators: name: Paci, Maxim
name: Fox, George E.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: 60506 Virology

description: Structural centers of motion (pivot points) in the ribosome have recently been identified by measurement of conformational changes in rRNA resulting from EF-G GTP hydrolysis. This series of measurements is extended here to the ribosome's interactions with the cofactor EF-Tu. Four recent EF-Tu bound ribosome structures were compared to unbound structures. A total of 16 pivots were identified, of which 4 are unique to the EF-Tu interaction. Pivots in the GTPase associated center and the sarcin-ricin loop omitted previously, are found to be mobile in response to both EF-Tu and EF-G binding. Pivots in the intersubunit bridge rRNAs are found to be cofactor specific. Head swiveling motions in the small subunit are observed in the EF-Tu bound structures that were trapped post GTP hydrolysis. As in the case of pivots associated with EF-G, the additional pivots described here are associated with weak points in the rRNA structures such as non-canonical pairs and bulge loops. The combined set of pivots should be regarded as a minimal set. Only several states available to the ribosome have been presented in this work. Future, precise crystal structures in conjunction with experimental data will likely show additional functional pivoting elements in the rRNA.
RoboSTEAM Project March 2020 videoconference
Creators: name: Conde-González, M. Á.
Publisher: name: Zenodo
Year: 2020
Subjects: RoboSTEAM, Erasmus+, STEAM, Robots, Computational Thinking, EU

description: Presentation and agenda of the March 4th 2020 videoconference of the RoboSTEAM Erasmus+ Project (Ref. 2018-1-ES01-KA201-050939)
description: RoboSTEAM (Integrating STEAM and computational thinking development by using robotics and physical devices) is a project funded under European Union ERASMUS+ KA2 – Cooperation and Innovation for Good Practices. Strategic Partnerships for school education Programme (2018-1-ES01-KA201-050939). The European Commission support for the production of this publication does not constitute an endorsement of the contents which reflects the views only of the authors, and the Commission cannot be held responsible for any use which may be made of the information contained therein.
Centers of motion associated with EF-Tu binding to the ribosome
Creators: name: Paci, Maxim
name: Fox, George E.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry
subject: 60506 Virology

description: Structural centers of motion (pivot points) in the ribosome have recently been identified by measurement of conformational changes in rRNA resulting from EF-G GTP hydrolysis. This series of measurements is extended here to the ribosome's interactions with the cofactor EF-Tu. Four recent EF-Tu bound ribosome structures were compared to unbound structures. A total of 16 pivots were identified, of which 4 are unique to the EF-Tu interaction. Pivots in the GTPase associated center and the sarcin-ricin loop omitted previously, are found to be mobile in response to both EF-Tu and EF-G binding. Pivots in the intersubunit bridge rRNAs are found to be cofactor specific. Head swiveling motions in the small subunit are observed in the EF-Tu bound structures that were trapped post GTP hydrolysis. As in the case of pivots associated with EF-G, the additional pivots described here are associated with weak points in the rRNA structures such as non-canonical pairs and bulge loops. The combined set of pivots should be regarded as a minimal set. Only several states available to the ribosome have been presented in this work. Future, precise crystal structures in conjunction with experimental data will likely show additional functional pivoting elements in the rRNA.
Centers of Motion Associated with EF-Tu Binding to the Ribosome
Creators: name: Paci, Maxim
name: Fox, George E.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: 60506 Virology

description: Structural centers of motion (pivot points) in the ribosome have recently been identified by measurement of conformational changes in rRNA resulting from EF-G GTP hydrolysis. This series of measurements is extended here to the ribosome's interactions with the cofactor EF-Tu. Four recent EF-Tu bound ribosome structures were compared to unbound structures. A total of sixteen pivots were identified, of which four are unique to the EF-Tu interaction. Pivots in the GTPase associated center and the sarcin-ricin loop omitted previously, are found to be mobile in response to both EF-Tu and EF-G binding. Pivots in the intersubunit bridge rRNAs are found to be cofactor specific. Head swiveling motions in the small subunit are observed in the EF-Tu bound structures that were trapped post GTP hydrolysis. As in the case of pivots associated with EF-G, the additional pivots described here are associated with weak points in the ribosomal RNA structures such as non-canonical pairs and bulge loops. The combined set of pivots should be regarded as a minimal set. Only several states available to the ribosome have been presented in this work. Future, precise crystal structures in conjunction with experimental data will likely show additional functional pivoting elements in the ribosomal RNA.