cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tevatron Top Results
Creators: name: Clement, Christophe
Publisher: name: arXiv
Year: 2006
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: I present the latest results from the CDF and D0 collaborations on top quark production (single top and top quark pair production) at the Tevatron proton-antiproton collider at sqrt(s) =1.96 TeV, measurements of the top quark decay properties such as the branching ratio B(t -> Wb), the W helicity in t -> Wb decays, and measurements of fundamental parameters such as the top quark charge and mass.
description: Proceedings of Flavor Physics & CP Violation Conference, Vancouver, 2006
Leptogenesis as an origin of dark matter and baryon asymmetries in the E6 inspired SUSY models
Creators: name: Nevzorov, R.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We explore leptogenesis within the E6 inspired U(1) extension of the MSSM in which exact custodial symmetry forbids tree-level flavour-changing transitions and the most dangerous baryon and lepton number violating operators. This supersymmetric (SUSY) model involves extra exotic matter beyond the MSSM. In the simplest phenomenologically viable scenarios the lightest exotic fermions are neutral and stable. These states should be substantially lighter than 1 eV forming hot dark matter in the Universe. The low-energy effective Lagrangian of the SUSY model under consideration possesses an approximate global U(1)_E symmetry associated with the exotic states. The U(1)_E symmetry is explicitly broken because of the interactions between the right-handed neutrino superfields and exotic matter supermultiplets. As a consequence the decays of the lightest right-handed neutrino/sneutrino give rise to both U(1)_E and U(1)_{B-L} asymmetries. When all right-handed neutrino/sneutrino are relatively light \sim 10^6-10^7 GeV the appropriate amount of the baryon asymmetry can be induced via these decays if the Yukawa couplings of the lightest right-handed neutrino superfields to the exotic matter supermultiplets vary between 10^{-4}-10^{-3}.
description: 17 pages, 1 figure
The dynamical structure of higher dimensional Chern-Simons theory
Creators: name: Banados, Maximo
name: Garay, Luis J.
name: Henneaux, Marc
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Higher dimensional Chern-Simons theories, even though constructed along the same topological pattern as in 2+1 dimensions, have been shown recently to have generically a non-vanishing number of degrees of freedom. In this paper, we carry out the complete Dirac Hamiltonian analysis (separation of first and second class constraints and calculation of the Dirac bracket) for a group GxU(1). We also study the algebra of surface charges that arise in the presence of boundaries and show that it is isomorphic to the WZW4 discussed in the literature. Some applications are then considered. It is shown, in particular, that Chern-Simons gravity in dimensions greater than or equal to five has a propagating torsion.
description: 24 pages, LaTeX2.09, no figures, minor bibliographical changes
Squeezed Fock state by inconclusive photon subtraction
Creators: name: Olivares, Stefano
name: Paris, Matteo G. A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We analyze in details the properties of the conditional state recently obtained by J. Wenger, et al. [Phys. Rev. Lett. {\bf 92}, 153601 (2004)] by means of inconclusive photon subtraction (IPS) on a squeezed vacuum state $S(r)\ket{0}$. The IPS process can be characterized by two parameters: the IPS transmissivity $τ$ and the photodetection quantum efficiency $η$. We found that the conditional state approaches the squeezed Fock state $S(r)\ket{1}$ when $τ,η\to 1$, i.e., in the limit of single-photon subtraction. For non-unit IPS transmissivity and efficiency, the conditioned state remains close to the target state, {\em i.e.} shows a high fidelity for a wide range of experimental parameters. The nonclassicality of the conditional state is also investigated and a nonclassicality threshold on the IPS parameters is derived.
description: 10 pages, 7 figures
See the Forest for the Trees: Examining Best Practice Collaboration in Forest Management Planning Processes
Creators: name: Kornhauser, Kailey
Publisher: name: University of Utah
Year: 2019
Subjects: Environmental management
Environmental studies

description: In 2012, the US Forest Service created a new planning rule for land management that included the use of collaborative methods and public involvement. Planning rules impact the Forest Service Management Plans for individual National Forests. The 2012 Planning Rule provides a very broadly defined version of collaboration. This thesis seeks to define collaboration using six characteristics of collaboration frequently mentioned in literature. This research also examines documents produced at the federal level of the Forest Service as well as two individual case studies of National Forests that are undergoing the plan revision process using the six factors of best practice collaboration to analyze the documents. Finally, this analysis concludes with recommendations to the Forest Service for better incorporation of best practice collaboration in land management planning.
Salad Days: work, Covenant, and the child
Creators: name: Blaylock, Nicholas
Publisher: name: University of Utah
Year: 2019
Subjects: Dance

description: This thesis has become an intermingling conversation between two threads. On one hand, I write in-depth reflections concerning my creative work, Salad Days, completed in partial fulfillment of the requirements for a Master of Fine Arts in Modern Dance. At the same, this is a personal manifesto. I simply ask myself why I made the choices I did, bringing me from micro-decisions to macro-concepts. I begin with what actually happened, how I approached the presentation of people working through physical and spatial challenges. I give context to my choices of sound, offering the work a specific mood. I am brought to simplicity in the creator's initiative, and how the artist can work towards the possibility of connection, rather than expecting it. This commitment takes me into a discussion on the culture of covenant. Here, I discern what I mean when I use the term covenant, where this was realized in the dancing, and the implications of such commitment. I make a distinction that, because covenant is unconditional, it calls us to live in the space between question and answer, the tension of having ability to learn, but inability to know all. Finally, I will make connections to my past while taking into account Dr. Maria Montessori's theories on education and Dr. Stuart Brown's expertise in play. I take a brief look into the Hebrew Scriptures to reveal this ancient culture's impressions of humanity. This culmination recognizes the essence of work and the culture of covenant to be foundational elements of our nature, the nature of the child, and that this is the call of Salad Days.
The Role of Kirrel3 in Hippocampal Mossy Fiber Synapse Development
Creators: name: Martin, Elizabeth Anne
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Molecular biology
subject: Neurosciences
subject: FOS: Clinical medicine

description: Synaptic target specificity, whereby neurons make distinct types of synapses with distinct target cells, is critical for proper brain function, yet the molecules driving this process are poorly understood. This work demonstrates that, contrary to established dogma, wildtype hippocampal mossy fiber (MF) filopodia do not synapse exclusively onto GABA neurons as previously thought, but instead synapse with similar frequency onto GABA neurons and CA3 neurons in developing mice. Moreover, loss of transmembrane cell adhesion molecule Kirrel3 selectively reduces MF filopodial synapses onto GABA neurons but not those made onto CA3 neurons nor DG-GABA en passant synapses. Consequently, Kirrel3 loss robustly increases CA3 neuron activity during development. In addition, rare Kirrel3 variants found in individuals with neurodevelopmental disorders reduce both cell-cell aggregation and specific synapse formation. In sum, the selective loss of MF filopodial synapses with GABA neurons likely underlies the hippocampal activity imbalance observed in Kirrel3 knockout mice and may impact neural function in patients with Kirrel3-dependent neurodevelopmental disorders. These findings demonstrate that subtle synaptic changes during development can greatly impact circuit function, solidify Kirrel3 as a bona fide synapse specificity molecule, and provide the first insight toward understanding the basis of Kirrel3-dependent neurodevelopmental disorder.
Chasing passive galaxies in the early Universe: a critical analysis in CANDELS GOODS-South
Creators: name: Merlin, E.
name: Fontana, A.
name: Castellano, M.
name: Santini, P.
name: Torelli, M.
name: Boutsia, K.
name: Wang, T.
name: Grazian, A.
name: Pentericci, L.
name: Schreiber, C.
name: Ciesla, L.
name: McLure, R.
name: Derriere, S.
name: Dunlop, J. S.
name: Elbaz, D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We search for passive galaxies at $z>3$ in the GOODS-South field, using different techniques based on photometric data, and paying attention to develop methods that are sensitive to objects that have become passive shortly before the epoch of observation. We use CANDELS HST catalogues, ultra-deep $Ks$ data and new IRAC photometry, performing spectral energy distribution fitting using models with abruptly quenched star formation histories. We then single out galaxies which are best fitted by a passively evolving model, and having only low probability $( < 5 \%)$ star-forming solutions. We verify the effects of including nebular lines emission, and we consider possible solutions at different redshifts. The number of selected sources dramatically depends on the models used in the SED fitting. Without including emission lines and with photometric redshifts fixed at the CANDELS estimate, we single out 30 candidates; the inclusion of nebular lines emission reduces the sample to 10 objects; allowing for solutions at different redshifts, only 2 galaxies survive as robust candidates. Most of the candidates are not far-infrared emitters, corroborating their association with passive galaxies. Our results translate into an upper limit in the number density of $\sim 0.173$ arcmin$^2$ above the detection limit. However, we conclude that the selection of passive galaxies at $z>3$ is still subject to significant uncertainties, being sensitive to assumptions in the SED modeling adopted and to the relatively low S/N of the objects. By means of dedicated simulations, we show that JWST will greatly enhance the accuracy, allowing for a much more robust classification.
description: 28 pages, 13 figures, 2 tables
The Roles of The Laminin Extracellular Matrix and Migratory Neural Crest Cells During Optic Cup Morphogenesis
Creators: name: Bryan, Chase Dallas
Publisher: name: University of Utah
Year: 2019
Subjects: Developmental biology
Cellular biology

description: The development of an organ involves establishment of its shape, which is often critical for proper function. Perhaps the most striking case where organ shape dictates function is in the vertebrate eye, where vision depends on many tissues taking on the correct shape, and becoming correctly oriented relative to all the other surrounding tissues. The basic shape of the eye is set up very early during embryogenesis, through development of the vertebrate optic cup. Disruptions to the early stages of optic cup morphogenesis can have profound effects on subsequent eye development and function. Therefore, understanding how the eye normally takes its shape during these early stages is critical to understand how the eye can become disrupted and cause vision loss or blindness. During optic cup morphogenesis, the developing eye is surrounded by a complex extracellular matrix, but the function of any given component of the extracellular matrix in this morphogenetic process has been unknown until now. Additionally, neural crest cells migrate around the optic cup during its development, but whether these cells are required for optic cup morphogenesis and how they shape the eye has remained mysterious until now. Here, we use the developing zebrafish optic cup to study the contribution of two extracellular matrix proteins during optic cup morphogenesis, laminin and nidogen. We find that both of these proteins are required for specific aspects of optic cup morphogenesis, and find that the neural crest which migrates around the developing eye is partially responsible for generating its extracellular matrix.
Effects of CYP2C11 gene knockout on the pharmacokinetics and pharmacodynamics of warfarin in rats
Creators: name: Ye, Huanying
name: Sui, Danjuan
name: Liu, Wei
name: Yuan, Yuannan
name: Ouyang, Zhen
name: Wei, Yuan
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: 1. CYP2C11 is the most abundant isoform of cytochrome P450s (CYPs) in male rats and is considered the main enzyme for warfarin metabolism. 2. To further access the in vivo function of CYP2C11 in warfarin metabolism and efficacy, a CYP2C11-null rat model was used to study warfarin metabolism with both in vitro and in vivo approaches. Prothrombin time (PT) of warfarin was also determined. 3. The maximum rate of metabolism (Vmax) and intrinsic clearance (CLint) of liver microsomes from CYP2C11-null males were reduced by 37 and 64%, respectively, compared to those in Sprague Dawley (S-D) rats. The Km of liver microsomes from CYP2C11-null males was increased by 73% compared to that of S-D rats. The time to reach the maximum plasma concentration (Tmax) of warfarin in CYP2C11-null males was significantly delayed compared to that in S-D males, and the CL rate was also reduced. The PT of CYP2C11-null rats was moderately longer than that of S-D rats. 4. In conclusion, the clearance rate of warfarin was mildly decreased and its anticoagulant effect was moderately increased in male rats following CYP2C11 gene knockout. CYP2C11 played a certain role in the clearance and efficacy of warfarin, while it did not seem to be essential.
title: 01_1126
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Secrete/d Pedagogies: Body Languaging and the Navigation of Traumatizing and Traumatized Space in the First-Year Composition Classroom
Creators: name: Meads, Rachel Gee
Publisher: name: University of Utah
Year: 2019
Subjects: Rhetoric

description: Secrete/d Pedagogy: Body Languaging and the Navigation of Traumatizing and Traumatized Space in the First-Year Composition Classroom, is an interdisciplinary exploration into the multimodal, multisensory phenomenon of languaging in and for schools. Beginning with an exploration into the forces that move, shape, and texture the writing classroom, this text steps into the phenomena of literacy, language, and the body, paying particular attention to the enfolded and unfolding histories of conquest through practices of language standardization that live within the bodies being schooled. By foregrounding bodily memory, emotion, felt sensation, and somatic stimuli, we can begin to see the role of the body in the design and disruption of language. I claim that the languaging body acts with agentic force within the first-year composition (FYC) classroom, re/citing, re/spawn/ding and trans/forming the inheritances of violence sculpting institutional affect and the standardization of particular linguistic forms. As this dissertation moves into the force of the body in language and expression, the expressions and sensations of the bodies who participated in this multivocal videocued ethnography will move the text as it attempts to answer the following questions: What body languaging practices are occurring within the first-year composition (FYC) classroom? And, how are teacher, students, and researcher making sense of body-based meaning- making resources, or not, within the FYC classroom? Poetry, oration, film, and scene headings will work together to fashion a text held together by the experiences of thebeings (writing students, writing teacher, and researcher) who composed the study. This text will do its best to be reflective and response(able) to the multimodal, multisensory phenomenon this is writing... in and for schools.
Metals in Star-Forming Galaxies at High Redshift
Creators: name: Leitherer, Claus
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The chemical composition of high-redshift galaxies is an important property that gives clues to their past history and future evolution. Measuring abundances in distant galaxies with current techniques is often a challenge, and the canonical metallicity indicators can often not be applied. I discuss currently available metallicity indicators based on stellar and interstellar absorption and emission lines, and assess their limitations and systematic uncertainties. Recent studies suggest that star-forming galaxies at redshift around 3 have heavy-element abundances already close to solar, in agreement with predictions from cosmological models.
description: 6 pages, 3 figures. Invited talk given at IAU Symp. 228, From Lithium to Uranium, Paris (France), 23 - 27 May, 2005. To be published in: IAU Symp. 228, From Lithium to Uranium, ed. V. Hill, P. Francois, & F. Primas (Cambridge: CUP), in press
title: Programme de la conférence du projet amorce LiDAR, ATRI 2
Creators: name: CCJ (UMR 7299)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017

description: Programme de la conférence du projet amorce LiDAR, ATRI 2, du 24 novembre 2014
description: Relation: http://labexmed.hypotheses.org/963
The Spiral Physics of Intelligence Becoming
Creators: name: Bostick, Devin
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Physics
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Artificial intelligence
subject: Nonlinear Dynamics

description: Main CODES Framework

Cover Abstract

The Spiral Physics of Intelligence Becoming reframes growth, mind, and reality through the lens of structured resonance rather than linear ascent.

Drawing from CODES (Chirality of Dynamic Emergent Systems), this paper reveals that intelligence is not a static possession nor a hierarchical achievement.

It is a breathing spiral: a dynamic chiral oscillation between actualization and transcendence across recursive coherence fields.

Through biological, psychological, and technological mappings, it demonstrates that sustained meaning and systemic resilience arise not from optimization or conquest, but from coherent breathing across scales.

Introducing the Spiral Law — Growth = Continuous Compression–Expansion Phase Dance — this work proposes measurable experimental predictions and systemic applications for education, AI, governance, and ecological stewardship.

Ultimately, The Spiral Physics of Intelligence Becoming restores the forgotten architecture of life:

the living Breath folding coherence through all existence.
SAMHD1 Activity Underlies Ifn Responses and Sex-Dependent Differences in Macrophage Infection by HIV-1
Creators: name: Szaniawski, Matthew Alan
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Virology

description: Human Immunodeficiency Virus type 1 (HIV-1) targets immune cells, including CD4+ T cells, macrophages, and dendritic cells (DC). Macrophages are critically important for their contributions to viral propagation and inflammation in vivo during infection, though the current understanding of host-pathogen interactions in this cell type remains deeply inadequate. A better understanding of how HIV-1 infects macrophages despite facing numerous cellular defenses may inform therapeutic approaches aimed at preventing HIV-1 infection and its sequelae. A major component of the anti-HIV-1 defense is SAM domain and HD domain-containing protein 1 (SAMHD1), a phosphohydrolase responsible for restricting the generation of double-stranded viral DNA (dsDNA) from a single-stranded RNA (ssRNA) genome. It functions by converting deoxynucleoside triphosphates (dNTP) to deoxynucleosides (dN) in non-cycling cells, a process dependent on tetramerization that is inhibited through threonine-592 (T592) phoshphorylation. We discovered that SAMHD1 activity is a critical determinant of HIV-1 infection in macrophages, and that despite its abundant expression, can exist in an inactive state (phosphor-T592) allowing macrophages to be highly susceptible to HIV-1. We found that biological sex is a major determinant of macrophage infectivity with HIV- 1, and that the relative susceptibility of male- versus female-derived macrophages hinges exclusively on SAMHD1 activity. Furthermore, we have established SAMHD1 as the principal effector through which diverse interferons (IFN) act in macrophages, and that activation of SAMHD1 through IFN signaling establishes a state of HIV-1 resistance. We find that cyclin-dependent kinase 1 (CDK1) is the major determinant of IFN-induced SAMHD1 activation, and that depletion of CDK1 through siRNA alone drives SAMHD1 activation in MDM. Interestingly, a variety of FDA-approved tyrosine kinase inhibitors (TKI) phenocopy the effects of IFNs, and their activity depends on their ability to activate SAMHD1. Furthermore, we find that macrophage infection with HIV-1 induces a similar state of protection from subsequent challenge, which correlates with activation of SAMHD1. Interestingly, this protection does not appear to involve the production of IFNs. Using phosphoproteomic and RNA-sequencing approaches, we have begun to unravel the pathways responsible for SAMHD1 activation resulting from HIV-1 sensing, IFN stimulation, and the use of TKIs, which exhibit overlapping but distinct mechanisms of action.
D. 7.1 - Programme and summary/outline of the project status and decisions taken at the Kick-off meeting
Creators: name: PISACANE, LUCIO
name: Tagliacozzo, Serena
name: Marchesini, Nicolò
name: Cellini, Marco
name: Crescimbene, Cristiana
name: Trussardi, Paola
Publisher: name: gEneSys Project
Year: 2023

description: This deliverable reports the programme and summary/outline of the project status and decisions taken at the Kick-off meeting. Also, the deliverable decribes the meeting and contains the slides that has been presented during the activities of the Kick-off meeting.
Additional file 10 of Comprehensive DNA methylation profiling of COVID-19 and hepatocellular carcinoma to identify common pathogenesis and potential therapeutic targets
Creators: name: Luo, Huiyan
name: Chen, Jixin
name: Jiang, Qiyin
name: Yu, Yifan
name: Yang, Miaolun
name: Luo, Yuehua
name: Wang, Xiongwen
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 10: Table S1 Top10 GO enrichment results.
Testing for redshift evolution of Type Ia supernovae using the strongly lensed PS1-10afx at $z=1.4$
Creators: name: Petrushevska, T.
name: Amanullah, R.
name: Bulla, M.
name: Kromer, M.
name: Ferretti, R.
name: Goobar, A.
name: Papadogiannakis, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The light from distant supernovae (SNe) can be magnified through gravitational lensing when a foreground galaxy is located along the line of sight. This line-up allows for detailed studies of SNe at high redshift that otherwise would not be possible. Spectroscopic observations of lensed high-redshift Type Ia supernovae (SNe Ia) are of particular interest since they can be used to test for evolution of their intrinsic properties. The use of SNe Ia for probing the cosmic expansion history has proven to be an extremely powerful method for measuring cosmological parameters. However, if systematic redshift-dependent properties are found, their usefulness for future surveys could be challenged. We investigate whether the spectroscopic properties of the strongly lensed and very distant SN Ia PS1-10afx at $z=1.4$ deviates from the well-studied populations of normal SNe Ia at nearby or intermediate distance. We created median spectra from nearby and intermediate-redshift spectroscopically normal SNe Ia from the literature at -5 and +1 days from light-curve maximum. We then compared these median spectra to those of PS1-10afx. We do not find signs of spectral evolution in PS1-10afx. The observed deviation between PS1-10afx and the median templates are within what is found for SNe at low- and intermediate-redshift. There is a noticeable broad feature centred at $\rm λ\sim 3500$~Å, which is present only to a lesser extent in individual low and intermediate redshift SN Ia spectra. From a comparison with a recently developed explosion model, we find this feature to be dominated by iron peak elements, in particular, singly ionized cobalt and chromium.
description: accepted for publication in section 4. Extragalactic astronomy of Astronomy and Astrophysics
دور أبعاد إدارة المعرفة في تحسين أداء المورد البشري داخل المنشآت الرياضية بالجزائر The role of knowledge management dimensions in improving the performance of human resources within sports facilities in Algeria
Creators: name: سعدودي, الشيخ
name: لاوسن, سليمان
Publisher: name: Zenodo
Year: 2022
Subjects: Knowledge management, Human resource, Sports facilities

description: The study aims to identify the role of the dimensions of knowledge management in improving the  erformance of the human resource within the sports facilities in Algeria, and regarding this research, we followed the descriptive approach, and relied on the questionnaire as a tool to verify the results, The research sampleconsisted of 30 employees who were chosen by the comprehensive survey method, after collecting the results and processing them statistically, The most important conclusion was reached that knowledge management has a major role within the sports facilities sector in particular, And that the process of improving the performance of the human resource taken by the employees in the facility results from employing the technological, organizational and social dimensions of knowledge management in order to improve this performance, The most important proposal is to develop the skills of employees and provide a clear strategic vision for the facility and its objectives, by supporting effective knowledge decisions for the facility.
Seismic analysis of the second ionization region of helium in the Sun: I. Sensitivity study and methodology
Creators: name: Monteiro, M. J. P. F. G.
name: Thompson, M. J.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The region of the second ionization of helium in the Sun is a narrow layer near the surface. Ionization induces a local change of the adiabatic exponent $Γ_1$, which produces a characteristic signature in the frequencies of p-modes. By adapting the method developed by (Monteiro et al. 1994), we propose a methodology for determining the properties of this region by studying such a signature in the frequencies of oscillation. Using solar data we illustrate how the signal from the helium ionization zone can be isolated. Using solar models with different physics -- theory of convection, equation of state and low temperature opacities -- we establish how the characteristics of the signal depend on the different aspects contributing to the structure in the ionization layer. We further discuss how the method can be used to measure the solar helium abundance in the envelope and to constrain the physics affecting this region of the Sun. The potential usefulness of the method we propose is shown. It may complement other inversion methods developed to study the solar structure and to determine the envelope helium abundance.
description: 11 pages, 9 figures. To appear in Monthly Notices of the Royal Astronomical Society
title: ADCO, Comptes du Petit-Cîteaux (1477-1491) (11 H 1179), f. 00329
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: comptes
subject: LaMOP

description: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Comptes du Petit-Cîteaux (1477-1491), Archives départementales de la Côte-d'Or, (11 H 1179), f. 00329, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
Four-dimensional integration by parts with differential renormalization as a method of evaluation of Feynman diagrams
Creators: name: Smirnov, V. A.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is shown how strictly four-dimensional integration by parts combined with differential renormalization and its infrared analogue can be applied for calculation of Feynman diagrams.
description: 6 pages, latex
Roles of Glycosyltransferases in drosophila development
Creators: name: Moulton, Matthew Jason
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Cellular biology
subject: Developmental biology

description: It is surprising that there are only about 80 described congenital diseases that result from mutations in any of the 1% of genes in the human genome (~200-250 genes) dedicated to protein glycosylation. It is these glycosylation events that provide tremendous protein diversity and contribute to proper protein folding, function, and subcellular localization. Thus, the rarity with which human congenital disorders of glycosylation (CDGs) are observed despite the myriad of genes involved in this process and the apparent critical role for proper protein form and function suggests that glycosylation is critical for proper development. However, the role of glycans in development has been largely understudied and there are only a few genetic models of human CDGs in existence. Glycosylation occurs by the enzymatic addition of sugar-derived molecules and is estimated to provide 10-104 times more diversity than the unmodified proteome alone. Glycans are present on the surface of nearly every cell within multicellular organisms and are capable of facilitating communication with the cell and its environment and with other cells and also have structural roles as critical components of extracellular matrix. However, the complexity of glycan formation makes it difficult to understand the diverse and pleiotropic roles glycans play in cellular biology. The utility of Drosophila to elucidate the role of glycans in development as well as disease has only been appreciated recently. Herein, I further demonstrate the utility of Drosophila to understand the roles of both N- and O-glycans in development and cell signaling. Furthermore, I utilize the fly to understand the biology of glycans in a human disorder of congenital disease, Peters Plus Syndrome. I demonstrate that the previously reported Dpp signal antagonism achieved by the sugar derivative UDP-N-Acetyglucosamine (GlcNAc) is carried out by the synthesis of a chondroitin-sulfate sink produced in the embryonic cardiac mesoderm and by the addition of GlcNAc to the type I receptor Saxophone to limit Dpp signal through Tkv exclusively. Furthermore, loss of the Drosophila ortholog of the human B3GLCT gene, sugarcoated, demonstrates a critical role for O-linked mucins in cell hypertrophic growth during larval development and oogenesis and demonstrates a potential role for human mucins in chondrocyte hypertrophy-an event required for the majority of human bone growth-and a potential mechanistic reason for growth defects observed in Peters Plus Syndrome patients.
Analysis platforms for Australian proteomics
Creators: name: Gustafsson, Ove Johan Ragnar
name: Padula, Matthew P
name: Willet, Cali E
name: Hyde, Cameron
name: Thang, W. C. Mike
name: Downton, Matthew
name: Beecroft, Sarah
name: Crossett, Ben
name: Sadowski, Pawel
name: Gray, Mark
name: Al Bkhetan, Ziad
name: Price, Gareth
name: Ward, Nigel
name: Manos, Steven
Publisher: name: Zenodo
Year: 2024

description: The transition of proteomics into a data rich discipline now demands access to scaled up compute and complex analysis pipelines. There is an opportunity to respond as a coordinated community to provide fit for purpose analysis platforms that will support Australian proteomics moving forward.

Today, the application of bioinformatics to proteomics is complicated by numerous and diverse software tools, the steep learning curve in the adoption of working on the command line, limited access to computational resources, and intimidating pathways to larger scale compute resources (e.g. national computational systems). Addressing these challenges is critical given the increase in both experimental complexity and data output size in proteomics. Solutions to these challenges include supporting access to fit-for-purpose software and compute systems, the details of which are defined by the proteomics community.

Since the finalisation of the Proteomics Bioinformatics Infrastructure Roadmap for Australia in 2022 [1], the Australian BioCommons has been leading the effort to tailor software and compute resources for proteomics, in close collaboration with the community and national compute providers. To date, the two key outcomes of this effort are the Proteomics Lab on Galaxy Australia [2] and the Australian BioCommons Leadership Share (ABLeS) [3].

The Galaxy Australia Proteomics Lab provides researchers with a fully-subsidised shared platform for point-and-click access to key software (MaxQuant, DIA-NN), interactive visualisation tools (LFQanalyst) and reference data that is specific to proteomics. Galaxy Australia is underpinned by national computational resources, and will be expanded where possible to accommodate day-to-day analysis requirements for proteomics researchers.

ABLeS is a novel access mechanism for national computing facilities (Pawsey Supercomputing Centre and National Computational Infrastructure (NCI)), supporting bioinformaticians to access compute at scale for software optimisation, production implementation of standard methods and creation of critical reference data. ABLeS intends to accelerate scaling and application of bioinformatics on national facilities, and to share the learnings from this work with the wider life science community. ABLeS is currently being used for large-scale testing and optimisation of DIA-NN at the NCI.

This presentation will outline how ABLeS and Proteomics Lab work, and how the Australian BioCommons and its partners will continue to evolve these activities in lock step with the changing requirements of Australian proteomics research.
Pebble accretion at the origin of water in Europa
Creators: name: Ronnet, Thomas
name: Mousis, Olivier
name: Vernazza, Pierre
Publisher: name: arXiv
Year: 2017
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Despite the fact that the observed gradient in water content among the Galilean satellites is globally consistent with a formation in a circum-Jovian disk on both sides of the snowline, the mechanisms that led to a low water mass fraction in Europa ($\sim$$8\%$) are not yet understood. Here, we present new modeling results of solids transport in the circum-Jovian disk accounting for aerodynamic drag, turbulent diffusion, surface temperature evolution and sublimation of water ice. We find that the water mass fraction of pebbles (e.g., solids with sizes of 10$^{-2}$ -- 1 m) as they drift inward is globally consistent with the current water content of the Galilean system. This opens the possibility that each satellite could have formed through pebble accretion within a delimited region whose boundaries were defined by the position of the snowline. This further implies that the migration of the forming satellites was tied to the evolution of the snowline so that Europa fully accreted from partially dehydrated material in the region just inside of the snowline.
description: Accepted for publication in ApJ
Additional file 11 of Comprehensive DNA methylation profiling of COVID-19 and hepatocellular carcinoma to identify common pathogenesis and potential therapeutic targets
Creators: name: Luo, Huiyan
name: Chen, Jixin
name: Jiang, Qiyin
name: Yu, Yifan
name: Yang, Miaolun
name: Luo, Yuehua
name: Wang, Xiongwen
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 11: Table S2. qPCR primers used in this study.
Optical generation of matter qubit graph states
Creators: name: Benjamin, S. C.
name: Eisert, J.
name: Stace, T. M.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We present a scheme for rapidly entangling matter qubits in order to create graph states for one-way quantum computing. The qubits can be simple 3-level systems in separate cavities. Coupling involves only local fields and a static (unswitched) linear optics network. Fusion of graph state sections occurs with, in principle, zero probability of damaging the nascent graph state. We avoid the finite thresholds of other schemes by operating on two entangled pairs, so that each generates exactly one photon. We do not require the relatively slow single qubit local flips to be applied during the growth phase: growth of the graph state can then become a purely optical process. The scheme naturally generates graph states with vertices of high degree and so is easily able to construct minimal graph states, with consequent resource savings. The most efficient approach will be to create new graph state edges even as qubits elsewhere are measured, in a `just in time' approach. An error analysis indicates that the scheme is relatively robust against imperfections in the apparatus.
description: 10 pages in 2 column format, includes 4 figures. Problems with figures resolved
The Role of MicroRNAs in Promoting FLT3-ITD-Induced Myeloid Malignancy
Creators: name: Wallace, Jared Andrew
Publisher: name: University of Utah
Year: 2019
Subjects: subject: Oncology
subject: Molecular biology
subject: Immunology
subject: FOS: Clinical medicine

description: MicroRNA expression is dysregulated in many human cancers, including hematopoietic malignancies. Among hematopoietic malignancies, acute myeloid leukemia (AML) carries a particularly poor prognosis, leading to over 10,000 deaths each year in the US alone. The most common genetic aberration in AML is a gain-of-function mutation in the FMS-like tyrosine kinase 3 (FLT3) receptor. FLT3 internal tandem duplication (ITD) occurs in ~30% of all AML cases, and confers a negative prognosis. MicroRNA expression has been shown to be highly dysregulated in FLT3-ITD+ AML; however, the functional relevance of many of these microRNAs on leukemic phenotypes remains unclear. We performed a genome-wide CRISPR-Cas9 screen to identify which microRNAs, and which of their putative mRNA targets, regulate FLT3-ITD+ AML cell growth. Our screen identified a number of microRNAs that function to suppress or promote FLT3-ITD+ AML cell growth, revealing that microRNAs are extensively integrated into the molecular networks that control tumor cell physiology. We also performed anticorrelation functional profiling to predict relevant microRNA-mRNA target pairs in this context, and identified miR-150 targeting of p53 as a critical relationship governing the growth of these cells. We validated one of our targets, miR-155, as a critical regulator of FLT3-ITD+ AML cell growth in vitro, where miR-155-deficient cells displayed a competitive growth disadvantage compared to cells with miR-155 intact. We extended these findings into an in vivo model of FLT3-ITD-driven myeloid malignancy, where mice containing a FLT3-ITD mutation but lacking miR-155 exhibited decreased myeloid expansion in the bone marrow, spleen, and blood compared to their FLT3-ITD miR-155+/+ counterparts. This phenotype was attributed to miR-155's role in promoting proliferation of the hematopoietic stem cell and myeloid progenitor cell compartments in the bone marrow. Further analysis revealed that miR-155 likely exerts these effects by regulating multiple pathways involved in cellular proliferation, including repressing the interferon response through targeting Cebpb, and activating AKT signaling through targeting of Ship1. These findings correlated with human AML data from The Cancer Genome Atlas dataset, where we found that FLT3-ITD+ AML samples had a decreased interferon signature and lower levels of Cebpb and Ship1 compared to FLT3-WT AML samples. Finally, we treated FLT3-ITD+ AML primary patient samples with a miR-155 inhibitor and observed decreased colony forming potential and increased apoptosis in these cells. These results suggest that miR-155 inhibition could be a novel therapeutic approach in FLT3-ITD+ AML.
On the Fractional Electric Charge of a Magnetic Monopole at Nonzero Temperature
Creators: name: Goldhaber, A.
name: Parwani, R.
name: Singh, H.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We extend recent discussions about the effect of nonzero temperature on the induced electric charge, due to CP violation, of a Dirac or an 't Hooft-Polyakov monopole. In particular, we determine the fractional electric charge of a very small 't Hooft-Polyakov monopole coupled to light fermions at nonzero temperature. If dyons with fractional electric charge exist in the Weinberg-Salam model, as recently suggested in the literature, then their charge too should be temperature dependent.
description: 7 pages, Latex file, One significant correction and other revisions
Suppression of vacancies boosts thermoelectric performance in type-I clathrates
Creators: name: Yan, Xinlin
name: Ikeda, Matthias
name: Zhang, Long
name: Bauer, Ernst
name: Rogl, Peter
name: Giester, Gerald
name: Prokofiev, Andrey
name: Paschen, Silke
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Intermetallic type-I clathrates continue to attract attention as promising thermoelectric materials. Here we present structural and thermoelectric properties of single crystalline Ba8(Cu,Ga,Ge,v)46, where v denotes a vacancy. By single crystal X-ray diffraction on crystals without Ga we find clear evidence for the presence of vacancies at the 6c site in the structure. With increasing Ga content, vacancies are successively filled. This increases the charge carrier mobility strongly, even within a small range of Ga substitution, leading to reduced electrical resistivity and enhanced thermoelectric performance. The largest figure of merit ZT =0.9 at 900 K is found for a single crystal of approximate composition Ba8Cu4.6Ga1.0Ge40.4. This value, that may further increase at higher temperatures, is one of the largest to date found in transition metal element-based clathrates.
description: 9 pages
Additional file 1 of Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma
Creators: name: Zhou, Xiangxiang
name: Chen, Na
name: Xu, Hongzhi
name: Zhou, Xiaoming
name: Wang, Jianhong
name: Fang, Xiaosheng
name: Zhang, Ya
name: Li, Ying
name: Yang, Juan
name: Wang, Xin
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Sequences of primers used to amplify sgYAP cut sites.