cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
MATHICSE Technical Report : Spectral methods for multiscale stochastic differential equations
Creators: name: Abdulle, Assyr
name: Pavliotis, Grigorios A.
name: Vaes, Urbain
Publisher: name: Écublens, MATHICSE
Year: 2019

description: This paper presents a new method for the solution of multiscale stochastic differential equations at the diffusive time scale. In contrast to averaging-based methods, e.g., the heterogeneous multiscale method (HMM) or the equation-free method, which rely on Monte Carlo simulations, in this paper we introduce a new numerical methodology that is based on aspectral method. In particular, we use an expansion in Hermite functions to approximate the solution of an appropriate Poisson equation, which is used in order to calculate the coefficients of the homogenized equation. Spectral convergence is proved under suitable assumptions. Numerical experiments corroborate the theory and illustrate the performance of the method. A comparison with the HMM and an application to singularly perturbed stochastic PDEs are also presented.
INFLYATSIYANING MOHIYATI VA ISHSIZLIK O'RTASIDAGI TESKARI BOG'LIQLIGI HAMDA ANTIINFLYATSIYA SIYOSATI
Creators: name: Z.M.Qudratova Samarqand iqtisodiyot va servis instituti talabasi Email: zqudratova0@gmail.com Telefon: +99891 945-38-02
Publisher: name: Zenodo
Year: 2025

description: Ushbu maqolada inflyatsiya atamasi mohiyati, uni hisoblash turlari, inflyatsiya va ishsizlik o‘rtasidagi teskari bog‘liqlikni nazariy jihatlari va uning iqtisodiyotga ta’siri o‘rganilgan,  hamda antiinflyatsiya siyosati to‘g‘risida tahlillar amalga oshirilgan.
Additional file 2 of Baseline [18F]GTP1 tau PET imaging is associated with subsequent cognitive decline in Alzheimer’s disease
Creators: name: Teng, Edmond
name: Manser, Paul T.
name: Sanabria Bohorquez, Sandra
name: Wildsmith, Kristin R.
name: Pickthorn, Karen
name: Baker, Suzanne L.
name: Ward, Michael
name: Kerchner, Geoffrey A.
name: Weimer, Robby M.
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Cell Biology
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Mental Health

description: Additional file 2: Supplemental Figure 1. Longitudinal change from baseline at each assessment timepoint using a mixed model repeated measure analysis on the Mini-Mental State Exam (MMSE), Clinical Dementia Rating Sum of Boxes (CDR-SB), 13-item version of the Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog13), and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Total Index. SE: standard error; BL: baseline; W26: Week 26 visit; W52: Week 52 visit; W78: Week 78 visit.
title: ADCO, Cinquième cartulaire de Saint-Étienne de Dijon (1664), Cart. 28 (G 132), 258 folios, f. 00238
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00238, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cinquième cartulaire de Saint-Étienne de Dijon (1664), Archives départementales de la Côte-d'Or, Cart. 28 (G 132), 258 folios, f. 00238, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
MATHICSE Technical Report : A fast gradient method for nonnegative sparse regression with self dictionary
Creators: name: Gillis, Nicola
name: Luce, Robert
Publisher: name: Écublens, MATHICSE
Year: 2019

description: Nonnegative matrix factorization (NMF) can be computed efficiently under the separability assumption, which asserts that all the columns of the input data matrix belong to the convex cone generated by only a few of its columns. The provably most robust methods to identify these basis columns are based on nonnegative sparse regression and self dictionary, and require the solution of large-scale convex optimization problems. In this paper we study a particular nonnegative sparse regression model with self dictionary. As opposed to previously proposed models, it is a smooth optimization problem where sparsity is enforced through appropriate linear constraints. We show that the Euclidean projection on the set defined by these constraints can be computed efficiently, and propose a fast gradient method to solve our model. We show the effectiveness of the approach compared to state-of-the-art methods on several synthetic data sets and real-world hyperspectral images.
CGM properties in VELA and NIHAO simulations; the OVI ionization mechanism: dependence on redshift, halo mass and radius
Creators: name: Roca-Fàbrega, S.
name: Dekel, A.
name: Faerman, Y.
name: Gnat, O.
name: Strawn, C.
name: Ceverino, D.
name: Primack, J.
name: Macciò, A. V.
name: Dutton, A. A.
name: Prochaska, J. X.
name: Stern, J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We study the components of cool and warm/hot gas in the circumgalactic medium (CGM) of simulated galaxies and address the relative production of OVI by photoionization versus collisional ionization, as a function of halo mass, redshift, and distance from the galaxy halo center. This is done utilizing two different suites of zoom-in hydro-cosmological simulations, VELA (6 halos; $z>1$) and NIHAO (18 halos; to $z=0$), which provide a broad theoretical basis because they use different codes and physical recipes for star formation and feedback. In all halos studied in this work, we find that collisional ionization by thermal electrons dominates at high redshift, while photoionization of cool or warm gas by the metagalactic radiation takes over near $z\sim2$. In halos of $\sim 10^{12}M_{\odot}$ and above, collisions become important again at $z<0.5$, while photoionization remains significant down to $z=0$ for less massive halos. In halos with $M_{\textrm v}>3\times10^{11}~M_{\odot}$, at $z\sim 0$ most of the photoionized OVI is in a warm, not cool, gas phase ($T\lesssim 3\times 10^5$~K). We also find that collisions are dominant in the central regions of halos, while photoionization is more significant at the outskirts, around $R_{\textrm v}$, even in massive halos. This too may be explained by the presence of warm gas or, in lower mass halos, by cool gas inflows.
MATHICSE Technical Report : A fast virtual surgery platform for many scenarios haemo-dynamics of patient-specific coronary artery bypass grafts
Creators: name: Ballarin, Francesco
name: Faggiano, Elena
name: Manzoni, Andrea
name: Rozza, Gianluigi
name: Quarteroni, Alfio
name: Ippolito, Sonia
name: Antona, Carlo
name: Scrofani, Roberto
Publisher: name: Écublens, MATHICSE
Year: 2019

description: A fast computational framework is devised to the study of several configurations of patient-specific coronary artery by-pass grafts. This is especially useful to perform a sensitivity analysis of the haemodynamics for different flow conditions occurring in native coronary arteries and bypass grafts, the investigation of the progression of the coronary artery disease and the choice of the most appropriate surgical procedure. A complete pipeline, from the acquisition of patient-specific medical images to fast parametrized computational simulations, is proposed. Complex surgical configurations employed in the clinical practice, such as Y-grafts and sequential grafts, are studied. A virtual surgery platform based on model reduction of unsteady Navier Stokes equations for blood dynamics is proposed to carry out sensitivity analyses in a very rapid and reliable way. A specialized geometrical parametrization is employed to compare the effect of stenosis and anastomosis variation on the outcome of the surgery in several relevant cases.
Poster about the project "Mapping Open-Science Communities, Organizations, and Events in Latin America." for the graduation of the CEF training course.
Creators: name: Loto, Patricia Andrea
name: Formoso, Jesica
Publisher: name: Zenodo
Year: 2025
Subjects: open science
community building
Community Participation Model

description: A graduation achievement from the 2023 "Community Engagement Fundamentals" training course, this poster presents the "Mapping Open-Science Communities, Organizations, and Events in Latin America" project. As a culmination of the skills and knowledge gained during the course led by the Center for Scientific Collaboration and Community Engagement (CSCCE), the poster demonstrates the practical application of their Community Participation Model in a real-world mapping initiative focused on the Latin American open-science ecosystem.
MATHICSE Technical Report : Analysis of the internodes method for non-conforming discretizations of elliptic equations
Creators: name: Gervasio, Paulo
name: Quarteroni, Alfio
Publisher: name: Écublens, MATHICSE
Year: 2019

description: INTERNODES is a general method to deal with non-conforming discretizations of second order partial differential equations on regions partitioned into two or several subdomains. It exploits two intergrid interpolation operators, one for transfering the Dirichlet trace across the interface, the others for the Neumann trace. In this paper we provide several interpretations of the method and we carry out its stability and convergence analysis. In every subdomain the original problem is discretized by the finite element method, using a priori non-matching grids and piecewise polynomials of different degree. Finally, we propose an efficient algorithm for the solution of the corresponding algebraic system.
MATHICSE Technical Report : Reduced order methods for uncertainty quantification problems
Creators: name: Chen, Peng
name: Quarteroni, Alfio
name: Rozza, Gianluigi
Publisher: name: Écublens, MATHICSE
Year: 2019

description: This work provides a review on reduced order methods in solving uncertainty quantification problems. A quick introduction of the reduced order methods, including proper orthogonal decomposition and greedy reduced basis methods, are presented along with the essential components of general greedy algorithm, a posteriori error estimation and Offline-Online decomposition. More advanced reduced order methods are then developed for solving typical uncertainty quantification problems involving pointwise evaluation and/or statistical integration, such as failure probability evaluation, Bayesian inverse problems and variational data assimilation. Three expository examples are provided to demonstrate the efficiency and accuracy of the reduced order methods, shedding the light on their potential for solving problems dealing with more general outputs, as well as time dependent, vectorial noncoercive parametrized problems.
Additional file 1 of Myricanol 5-fluorobenzyloxy ether regulation of survivin pathway inhibits human lung adenocarcinoma A549 cells growth in vitro
Creators: name: Dai, Guan-hai
name: Chen, Xuan
name: Ren, Ze-ming
name: Dai, Chen-jie
name: Tong, Ye-ling
name: Chai, Ke-qun
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Original blot images.
MATHICSE Technical Report : Efficient model reduction of parametrized systems by matrix discrete empirical interpolation
Creators: name: Negri, Federico
name: Manzoni, Andrea
name: Amsallem, David
Publisher: name: Écublens, MATHICSE
Year: 2019

description: In this work, we apply a Matrix version of the so-called Discrete Empirical Interpolation (MDEIM) for the efficient reduction of nonaffine parametrized systems arising from the discretization of linear partial differential equations. Dealing with affinely parametrized operators is crucial in order to enhance the online solution of reduced-order models (ROMs). However, in many cases such an affine decomposition is not readily available, and must be recovered through (often) intrusive procedures, such as the empirical interpolation method (EIM) and its discrete variant DEIM. In this paper we show that MDEIM represents a very efficient approach to deal with complex physical and geometrical parametrizations in a non-intrusive, efficient and purely algebraic way. We propose different strategies to combine MDEIM with a state approximation resulting either from a reduced basis greedy approach or Proper Orthogonal Decomposition. A posteriori error estimates accounting for the MDEIM error are also developed in the case of parametrized elliptic and parabolic equations. Finally, the capability of MDEIM to generate accurate and efficient ROMs is demonstrated on the solution of two computationally-intensive classes of problems occurring in engineering contexts, namely PDE-constrained shape optimization and parametrized coupled problems.
MOESM1 of Nuclear and chloroplast DNA phylogeography suggests an Early Miocene southward expansion of Lithocarpus (Fagaceae) on the Asian continent and islands
Creators: name: Chih-Kai Yang
name: Yu-Chung Chiang
name: Huang, Bing-Hong
name: Ju, Li-Ping
name: Pei-Chun Liao
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 1: Table S1. Collecting sites and distribution. Table S2. Best substitution models for the atpB-rbcL and ITS used in the Bayesian analyses. Table S3. T Statistical summary of asymmetric values for the among-lineage diversification rate variation in the phylogenetic topologies. Table S4. Testing for diversification rate variation models by ∆AICRC test statistic. Figure S1. The phylogenetic tree reconstructed by cpDNA atpB-rbcL spacer and nrITS under the Yule’s pure-birth speciation model. Samples that were identified as the same species but represented at different clades in the gene trees (supplementary) were separated to different OTUs. Bold lines indicate the lineages grouping with posterior probability > 80%; node labels are the splitting time (unit: mya); node bar is the 95% highest posterior density interval (HPD) of the splitting time. The nodes probably have diversification rate shift were labeled by nodes i and ii of cpDNA tree and nodes a and b of ntITS tree. The testing results of diversification-rate shift of descendents of nodes i, ii, a, and b inferred by delta-statistics were indicated in the inner table. Figure S2. Biogeographic inferences by cpDNA+nrITS (Fig. 2A). (A) Biogeographic inference under the DEC model. Lineages with bold and thin lines indicate the lineages derived from nodes (ancestral areas) with likelihood > 0.7 and > 0.5, respectively. Likelihood less than 0.5 are treated as unknown (black lineages). (B) Biogeographic inference under the S-DIVA model. The dispersal (d) or vicariance (v) events with a posterior probability > 0.5 are marked in the node. The yellow dots indicate the events of range transition inferred by both dispersal and vicariance events. The open dots indicate that thebiogeographic distribuion of deriving lineages were explained as consequences of dispersal events. Figure S3. Biogeographic inferences by cpDNA (Fig. 3). (A) Biogeographic inference under the DEC model. (B) Biogeographic inference under the S-DIVA model. Figure S4. Biogeographic inferences by nrITS (Fig. 4). (A) Biogeographic inference under the DEC model. (B) Biogeographic inference under the S-DIVA model.
Library of high-resolution UES echelle spectra of F, G, K and M field dwarf stars
Creators: name: Montes, D.
name: Martin, E. L.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present a library of Utrecht echelle spectrograph (UES) observations of a sample of F, G, K and M field dwarf stars covering the spectral range from 4800 AA to 10600 AA with a resolution of 55000. These spectra include some of the spectral lines most widely used as optical and near-infrared indicators of chromospheric activity such as H_beta, Mg I b triplet, Na I D_1, D_2, He I D_3, H_alpha, and Ca II IRT lines, as well as a large number of photospheric lines which can also be affected by chromospheric activity. The spectra have been compiled with the aim of providing a set of standards observed at high-resolution to be used in the application of the spectral subtraction technique to obtain the active-chromosphere contribution to these lines in chromospherically active single and binary stars. This library can also be used for spectral classification purposes. A digital version with all the spectra is available via ftp and the World Wide Web (WWW) in both ASCII and FITS formats.
description: Latex file with 5 figures using l-aa.sty and psfig.sty. Full postscript (text and figures) available at http://www.ucm.es/OTROS/Astrof/fgkmsl/UESfgkmsl.html Accepted for publication in: Astronomy and Astrophysics Supplements
Matrix String Theory and its Moduli Space
Creators: name: Bonelli, G.
name: Bonora, L.
name: Nesti, F.
name: Tomasiello, A.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The correspondence between Matrix String Theory in the strong coupling limit and IIA superstring theory can be shown by means of the instanton solutions of the former. We construct the general instanton solutions of Matrix String Theory which interpolate between given initial and final string configurations. Each instanton is characterized by a Riemann surface of genus h with n punctures, which is realized as a plane curve. We study the moduli space of such plane curves and find out that, at finite N, it is a discretized version of the moduli space of Riemann surfaces: instead of 3h-3+n its complex dimensions are 2h-3+n, the remaining h dimensions being discrete. It turns out that as $N$ tends to infinity, these discrete dimensions become continuous, and one recovers the full moduli space of string interaction theory.
description: 30 pages, LaTeX, JHEP.cls class file, minor corrections
MATHICSE Technical Report : Riemannian optimization for high-dimensional tensor completion
Creators: name: Steinlechner, Michael Maximilian
Publisher: name: Écublens, MATHICSE
Year: 2019

description: Tensor completion aims to reconstruct a high-dimensional data set with a large fraction of missing entries. The assumption of low-rank structure in the underlying original data allows us to cast the completion problem into an optimization problem restricted to the manifold of fixed-rank tensors. Elements of this smooth embedded submanifold can be efficiently represented in the tensor train (TT) or matrix product states (MPS) format with storage complexity scaling linearly with the number of dimensions. We present a nonlinear conjugate gradient scheme within the framework of Riemannian optimization which exploits this favorable scaling. Numerical experiments and comparison to existing methods show the effectiveness of our approach for the approximation of multivariate functions. Finally, we show that our algorithm can obtain competitive reconstructions from uniform random sampling of few entries of compared to adaptive sampling techniques such as cross-approximation.
MATHICSE Technical Report : An algorithm for computing minimal Geršgorin sets
Creators: name: Kostić, V. R.
name: Miedlar, A.
name: Cvetković, LJ.
Publisher: name: Écublens, MATHICSE
Year: 2019

description: The first algorithms for computing the minimal Geršgorn set were developed by Varga et all. in [17] for the use on small and medium size (dense) matrices. Here, we first discuss the existing methods and present a new approach based on the modified Newton’s method to find zeros of the parameter dependent left-most eigenvalue of a Z-matrix. Additionally, sampling technique used in the original work is replaced by a special curve tracing procedure. The advantages of the new approach are presented on several test examples that arise in practical applications.
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 180 (11 H 755), 83 folios, f. 0149
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 180 (11 H 755), 83 folios, f. 0149, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 180 (11 H 755), 83 folios, f. 0149, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Additional file 1: of Feasibility and acceptability of a proposed trial of acupuncture as an adjunct to lifestyle interventions for weight loss in Polycystic Ovary Syndrome: a qualitative study
Creators: name: Ee, Carolyn
name: Smith, Caroline
name: Costello, Michael
name: MacMillan, Freya
name: Moran, Lisa
name: Baylock, Brandi
name: Teede, Helena
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additional Quotes. Additional quotes from the study, not included in the manuscript. (PDF 57 kb)
MATHICSE Technical Report : Isogeometric analysis of high order partial differential equations on surfaces
Creators: name: Bartezzaghi, Andrea
name: Dede', Luca
name: Quarteroni, Alfio
Publisher: name: Écublens, MATHICSE
Year: 2019

description: We consider the numerical approximation of high order Partial Differential Equations (PDEs) defined on surfaces in the three dimensional space, with particular emphasis on closed surfaces. We consider computational domains that can be represented by B-splines or NURBS, as for example the sphere, and we spatially discretize the PDEs by means of NURBS-based Isogeometric Analysis in the framework of the standard Galerkin method. We numerically solve benchmark Laplace-Beltrami problems of the fourth and sixth order, as well as the corresponding eigenvalue problems, with the goal of analyzing the role of the continuity of the NURBS basis functions on closed surfaces. In this respect, we show that the use of globally high order continuous basis functions, as allowed by the construction of periodic NURBS, leads to the efficient solution of the high order PDEs. Finally, we consider the numerical solution of high order phase field problems on closed surfaces, namely the Cahn-Hilliard and crystal equations.
Anonymity and Confidentiality in Secure Distributed Simulation
Creators: name: Magnani, Antonio
name: D'Angelo, Gabriele
name: Ferretti, Stefano
name: Marzolla, Moreno
Publisher: name: arXiv
Year: 2018
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Cryptography and Security (cs.CR)
subject: Multiagent Systems (cs.MA)
subject: Performance (cs.PF)
subject: FOS: Computer and information sciences

description: Research on data confidentiality, integrity and availability is gaining momentum in the ICT community, due to the intrinsically insecure nature of the Internet. While many distributed systems and services are now based on secure communication protocols to avoid eavesdropping and protect confidentiality, the techniques usually employed in distributed simulations do not consider these issues at all. This is probably due to the fact that many real-world simulators rely on monolithic, offline approaches and therefore the issues above do not apply. However, the complexity of the systems to be simulated, and the rise of distributed and cloud based simulation, now impose the adoption of secure simulation architectures. This paper presents a solution to ensure both anonymity and confidentiality in distributed simulations. A performance evaluation based on an anonymized distributed simulator is used for quantifying the performance penalty for being anonymous. The obtained results show that this is a viable solution.
description: Proceedings of the IEEE/ACM International Symposium on Distributed Simulation and Real Time Applications (DS-RT 2018)
Additional file 11: of Dissection of the molecular bases of genotype x environment interactions: a study of phenotypic plasticity of Saccharomyces cerevisiae in grape juices
Creators: name: Peltier, Emilien
name: Sharma, Vikas
name: Raga, Maria Martí
name: Roncoroni, Miguel
name: Bernard, Margaux
name: Jiranek, Vladimir
name: Gibon, Yves
name: Marullo, Philippe
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: Figure S5. Variation of QTL effect according to condition. For each QTL, the values shown are the difference between the phenotypic values measured for all the segregant that inherited the allele of SB or M2 minus those that inherited from GN or F15. A star means a significant difference (Wilcoxon, α = 0.05). (PDF 25 kb)
title: Fluorescence-based pH-shift assay with wide application scope for high-throughput determination of enzymatic activity in enzyme mining and engineering
Creators: name: Sunder, Avinash Vellore
name: Reif, Marie-Luise
name: Fessner, Wolf-Dieter
Publisher: name: The Royal Society of Chemistry
Year: 2025

description: A number of enzymes important for biocatalyst development or as drug targets are associated with a pH shift during their catalytic reaction, owing to the concommitant release or uptake of protons. Here, we show that an enzyme assay developed using the fluorescent pH indicator HPTS can be adapted for reliable and continuous activity determination of representative enzymes from multiple EC classes that operate in the viable pH range 5.5–8.5, using ratiometric measurement (F₄₈₅/F₄₀₅). Kinetic measurements obtained with this method closely match literature values determined using other assay types. Further, the assay was employed to screen variants of transketolase from Geobacillus stearothermophilus (TKgst) aimed at engineering substrate promiscuity and remote enantioselectivity for 3-hydroxyaldehydes. The fluorescence-based assay displayed 70-fold improved sensitivity in comparison to an absorption-based assay for transketolase screening, with a limit of detection of 0.044 mM and Z-factor of 0.52. Double-site mutagenesis at the G264 and S385 positions yielded variants with 5–15-fold increased activity on the tested 3-hydroxyaldehydes compared to the TKgst (L382F) base variant. Although the directed evolution engineering strategy did not achieve significant remote enantioselectivity in this first round of mutagenesis, the simple fluorescence-based pH-shift assay was shown to be useful as a versatile primary high-throughput screen for in vitro enzyme engineering.
MATHICSE Technical Report : Reduced basis approximation and a posteriori error estimates for parametrized elliptic eigenvalue problems
Creators: name: Fumagalli, Ivan
name: Manzoni, Andrea
name: Parolini, Nicola
name: Verani, Marco
Publisher: name: Écublens, MATHICSE
Year: 2019

description: We develop a new reduced basis (RB) method for the rapid and reliable approximation of parametrized elliptic eigenvalue problems. The method hinges upon dual weighted residual type a posteriori error indicators which estimate, for any value of the parameters, the error between the high-fidelity finite element approximation of the first eigenpair and the corresponding reduced basis approximation. The proposed error estimators are exploited not only to certify the RB approximation with respect to the high-fidelity one, but also to set up a greedy algorithm for the offline construction of a reduced basis space. Several numerical experiments show the overall validity of the proposed RB approach.
Black Holes, Branes and Superconformal Symmetry
Creators: name: Kallosh, Renata
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The main focus of this lecture is on extended objects in adS*S bosonic backgrounds with unbroken supersymmetry. The backgrounds are argued to be exact, special consideration are given to the non-maximal supersymmetry case. The near horizon superspace construction is explained. The superconformal symmetry appears in the worldvolume actions as the superisometry of the near horizon superspace, like the superPoincare symmetry of GS superstring and BST supermembrane in the flat superspace. The issues in gauge fixing of local kappa-symmetry are reviewed. We describe the features of the gauge-fixed IIB superstring in adS(5)*S(5) background with RR 5-form. From a truncated boundary version of it we derive an analytic N=2 off shell harmonic superspace of Yang-Mills theory. The reality condition of the analytic subspace, which includes the antipodal map on the sphere, has a simple meaning of the symmetry of the string action in the curved space. The relevant issues of black holes and superconformal mechanics are addressed.
description: 34 pages, Latex. To be published in the Proceedings of a conference held in Corfu, Greece in September 1998. Improvement in Sec. 3.3
Digital compensation of the side-band-rejection ratio in a fully analog 2SB sub-millimeter receiver
Creators: name: Rodriguez, R.
name: Finger, R.
name: Mena, F. P.
name: Alvear, A.
name: Fuentes, R.
name: Khudchenko, A.
name: Hesper, R.
name: Baryshev, A. M.
name: Reyes, N.
name: Bronfman, L.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In observational radio astronomy, sideband-separating receivers are preferred, particularly under high atmospheric noise, which is usually the case in the sub-millimeter range. However, obtaining a good rejection ratio between the two sidebands is difficult since, unavoidably, imbalances in the different analog components appear. We describe a method to correct these imbalances without making any change in the analog part of the sideband-separating receiver, specifically, keeping the intermediate-frequency hybrid in place. This opens the possibility of implementing the method in any existing receiver. We have built hardware to demonstrate the validity of the method and tested it on a fully analog receiver operating between 600 and 720GHz. We have tested the stability of calibration and performance vs time and after full resets of the receiver. We have performed an error analysis to compare the digital compensation in two configurations of analog receivers, with and without intermediate frequency (IF) hybrid. An average compensated sideband rejection ratio of 46dB is obtained. Degradation of the compensated sideband rejection ratio on time and after several resets of the receiver is minimal. A receiver with an IF hybrid is more robust to systematic errors. Moreover, we have shown that the intrinsic random errors in calibration have the same impact for configuration without IF hybrid and for a configuration with IF hybrid with analog rejection ratio better than 10dB. Compensated rejection ratios above 40dB are obtained even in the presence of high analog rejection. The method is robust allowing its use under normal operational conditions at any telescope. We also demonstrate that a full analog receiver is more robust against systematic errors. Finally, the error bars associated to the compensated rejection ratio are almost independent of whether IF hybrid is present or not.
Polarization Phenomena by Deuteron Fragmentation into Pions
Creators: name: Illarionov, A. Yu.
name: Litvinenko, A. G.
name: Lykasov, G. I.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The fragmentation of deuterons into pions emitted forward in the kinematic region forbidden for free nucleon-nucleon collisions is analyzed. The inclusive relativistic invariant spectrum of pions and the tensor analyzing power T_{20} are investigated within the framework of an impulse approximation using different kinds of the deuteron wave function. The influence of P-wave inclusion in the deuteron wave function is studied, too. The invariant spectrum is shown to be more sensitive to the amplitude of the $NN \to πX$ process than the tensor analyzing power T_{20}. It is shown that the inclusion of the non-nucleon degrees of freedom in a deuteron results a satisfactory description of experimental data about the inclusive pion spectrum and improves the description of data about T_{20}. According to the experimental data, T_{20} has the positive sign and very small values, less than 0.2, what contradicts to the theoretical calculations ignoring these degrees of freedom.
description: 18 pages, 8 eps figures, 1 picture - svjour.cls required; enlarged new version with corrections and additional figure. The Abstract and the section "Summary and outlook" have been also corrected. Final version to appear in Eur.Phys.J. A. A talk given at the International Workshop "Symmetries and Spin" (July 17-22, Prague, Czech Republic)
Photoproduction of the Eta-Prime Mesons as a New Tool to Probe Baryon Resonances
Creators: name: Zhang, J. -F.
name: Mukhopadhyay, Nimai C.
name: Benmerrouche, M.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We examine eta prime photoproduction, as a novel tool to study baryon resonances around 2 GeV, of particular interest to the quark shell model, which predicts a number of them. We find important roles of the form factors at the strong vertices, and show that the N^*(2080) can be probed efficiently by this reaction.
description: Will be published in Phys. Rev. C
Additional file 1: of The effects of normovolemic anemia and blood transfusion on cerebral microcirculation after severe head injury
Creators: name: Bellapart, Judith
name: Cuthbertson, Kylie
name: Kimble Dunster
name: Diab, Sara
name: Platts, David
name: Raffel, Christopher
name: Gabrielian, Levon
name: Barnett, Adrian
name: Paratz, Jennifer
name: Boots, Rob
name: Fraser, John
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 60506 Virology

description: Metabolic variables. (DOCX 119Â kb)
Additional file 3 of Baseline [18F]GTP1 tau PET imaging is associated with subsequent cognitive decline in Alzheimer’s disease
Creators: name: Teng, Edmond
name: Manser, Paul T.
name: Sanabria Bohorquez, Sandra
name: Wildsmith, Kristin R.
name: Pickthorn, Karen
name: Baker, Suzanne L.
name: Ward, Michael
name: Kerchner, Geoffrey A.
name: Weimer, Robby M.
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Cell Biology
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Mental Health

description: Additional file 3: Supplemental Figure 2. Scatterplots of baseline [18F]GTP1 SUVR versus annualized change scores calculated via estimated slopes on the Mini-Mental State Exam (MMSE), Clinical Dementia Rating Sum of Boxes (CDR-SB), 13-item version of the Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog13), and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Total Index in the cognitively normal (CN) and prodromal (Pro), mild (Mild), and moderate (Mod) AD groups in the (A) whole cortical gray, (B) temporal, (C) Braak I/II, (D) Braak III/IV, and (E) Braak V/VI ROIs.
On the regularity of static axially symmetric solutions in SU(2) Yang-Mills-dilaton theory
Creators: name: Kleihaus, B.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The regularity of static axially symmetric solutions in SU(2) Yang-Mills-dilaton theory is examined. We show that the solutions obtained previously within a singular Ansatz for the non-abelian gauge field can be gauge transformed into a regular form. The local form of the gauge transformation is given on the singular axis and at the origin.
description: 18 pages, no figures, LaTex format using RevTex, minor typos corrected, final version to appear in Phys. Rev. D
The Nature of Spectral Transitions in Accreting Black Holes: The Case of Cyg X-1
Creators: name: Poutanen, Juri
name: Krolik, Julian
name: Ryde, Felix
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Accreting black holes radiate in one of several spectral states, switching from one to another for reasons that are as yet not understood. Using the best studied example, Cyg X-1, we identify the geometry and physical conditions characterizing these states. In particular, we show that in the hard state most of the accretion energy is dissipated in a corona-like structure which fills the inner few tens of gravitational radii around the black hole and has Compton optical depth of order unity. In this state, an optically thick accretion disc extends out to greater distance, but penetrates only a short way into the coronal region. In the soft state, the optically thick disc moves inward and receives the majority of the dissipated energy, while the "corona" becomes optically thin and extends around much of the inner disc. The mass accretion rate in both states is $~10^{-8} M_{\odot}$ yr$^{-1}$.
description: 5 pages; mn style; 2 postscript figures; submitted to MNRAS Letters
MATHICSE Technical Report : Semi-implicit BDF time discretization of the Navier-Stokes equations with VMS-LES modeling in a High Performance Computing framework
Creators: name: Forti, Davide
name: Dede', Luca
Publisher: name: Écublens, MATHICSE
Year: 2019

description: In this paper, we propose a semi–implicit approach for the time discretization of the Navier–Stokes equations with Variational Multiscale–Large Eddy Simulation turbulence modeling (VMS–LES). For the spatial approximation of the problem, we use the Finite Element method, while we employ the Backward Differentiation Formulas (BDF) for the time discretization. We treat the nonlinear terms arising in the variational formulation of the problem with a semi–implicit approach leading to a linear system associated to the fully discrete problem which needs to be assembled and solved only once at each discrete time instance. We solvet his linear system by means of the GMRES method by employing a multigrid (ML) right preconditioner for the parallel setting. We validate the proposed fully discrete scheme towards the benchmark problem of the flow past a squared cylinder at high Reynolds number and we show the computational efficiency and scalability results of the solver in a High Performance Computing framework.
title: Environmental Justice and Resilience in the Niger Delta
Creators: name: Afinotan, Urenmisan
Publisher: name: University of Dundee
publisherIdentifier: https://ror.org/03h2bxq36
publisherIdentifierScheme: ROR
Year: 2022

description: The Niger Delta is a complex socio-ecological system that is rich in natural resources and biodiversity and has suffered decades of unabated environmental degradation characterised by violent agitation and conflict. This has systematically affected the socio-ecological resilience of the region, severely impacted its ecological sustainability and sustainable development, and has led to claims of environmental injustice in the Niger Delta. The laws affecting environmental justice in the region are claimed to be unjust and ineffective in promoting environmental justice and resilience.

Accordingly, this thesis explores the concepts of environmental justice and resilience and investigates the connection between them in the context of the Niger Delta. Five key criteria common to both concepts are developed into a paradigm called ‘just resilience’ and are identified as crucial for resilience and environmental justice in the Niger Delta. These criteria are access to land, access to resources, access to environmental information, public participation in environmental decision-making, and access to justice. Making use of doctrinal and socio-legal methodologies, and the capabilities approach as the core frame of analysis, these five criteria are used in this thesis to critically analyse specific laws affecting environmental justice and resilience in the Niger Delta to determine if they promote or impair just resilience in the region.

The thesis concludes that ‘just resilience’ is crucial for the ecological sustainability and the sustainable development of the region. However, resilience in the Niger Delta cannot be achieved without environmental justice. Yet, the laws affecting environmental justice in the Niger Delta generally impede rather than provide the capabilities necessary for it, thereby diminishing socio-ecological resilience, inducing conflict and impairing the overall ecological sustainability and sustainable development of the region. To enable the capabilities necessary for environmental justice and resilience, the thesis recommends that extensive amendments and/or repeals must be made to specific laws that affect just resilience in the Niger Delta.
MATHICSE Technical Report : Subspace acceleration for large-scale parameter-dependent Hermitian eigenproblems
Creators: name: Sirkovic, Petar
name: Kressner, Daniel
Publisher: name: Écublens, MATHICSE
Year: 2019

description: This work is concerned with approximating the smallest eigenvalue of a parameter-dependent Hermitian matrix A(μ) for many parameter values μ ∈ RP. The design of reliable and efficient algorithms for addressing this task is of importance in a variety of applications. Most notably, it plays a crucial role in estimating the error of reduced basis methods for parametrized partial differential equations. The current state-of-the-art approach, the so called Successive Constraint Method (SCM), addresses affine linear parameter dependencies by combining sampled Rayleigh quotients with linear programming techniques. In this work, we propose a subspace approach that additionally incorporates the sampled eigenvectors of A(μ) and implicitly exploits their smoothness properties. Like SCM, our approach results in rigorous lower and upper bounds for the smallest eigenvalues on D. Theoretical and experimental evidence is given to demonstrate that our approach represents a significant improvement over SCM in the sense that the bounds are often much tighter, at negligible additional cost.
Reassessing Exoplanet Light Curves with a Thermal Model
Creators: name: Adams, Arthur D.
name: Laughlin, Gregory
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present a uniform assessment of existing near-infrared Spitzer Space Telescope observations of planet-bearing stars. Using a simple four-parameter blackbody thermal model, we analyze stars for which photometry in at least one of Spitzer's IRAC bands has been obtained over either the entirety or a significant fraction of the planetary orbit. Systems in this category comprise ten well-studied systems with Hot Jupiters on circular or near-circular orbits (HAT-P-7, HD 149026, HD 189733, HD 209458, WASP-12, WASP-14, WASP-18, WASP-19, WASP-33, and WASP-43), as well as three stars harboring planets on significantly eccentric orbits (GJ 436, HAT-P-2, and HD 80606). We find that our simple model, in almost all cases, accurately reproduces the minimum and maximum planetary emission, as well as the phase offsets of these extrema with respect to transits/secondary eclipses. For one notable exception, WASP-12 b, adding an additional parameter to account for its tidal distortion is not sufficient to reproduce its photometric features. Full-orbit photometry is available in multiple wavelengths for 10 planets. We find that the returned parameter values for independent fits to each band are largely in agreement. However, disagreements in night-side temperature suggest distinct atmospheric layers, each with their own characteristic minimum temperature. In addition, a diversity in albedos suggests variation in opacity of the photospheres. While previous works have pointed out trends in photometric features based on system properties, we cannot conclusively identify analogous trends for physical model parameters. To make the connection between full-phase data and physical models more robust, a higher signal-to-noise must come from both increased resolution and a careful treatment of instrumental systematics.
description: 30 pages, 8 figures, 5 tables, accepted for publication in AJ