cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
CRKSPH - A Conservative Reproducing Kernel Smoothed Particle Hydrodynamics Scheme
Creators: name: Frontiere, Nicholas
name: Raskin, Cody D.
name: Owen, J. Michael
Publisher: name: arXiv
Year: 2016
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We present a formulation of smoothed particle hydrodynamics (SPH) that utilizes a first-order consistent reproducing kernel, a smoothing function that exactly interpolates linear fields with particle tracers. Previous formulations using reproducing kernel (RK) interpolation have had difficulties maintaining conservation of momentum due to the fact the RK kernels are not, in general, spatially symmetric. Here, we utilize a reformulation of the fluid equations such that mass, linear momentum, and energy are all rigorously conserved without any assumption about kernel symmetries, while additionally maintaining approximate angular momentum conservation. Our approach starts from a rigorously consistent interpolation theory, where we derive the evolution equations to enforce the appropriate conservation properties, at the sacrifice of full consistency in the momentum equation. Additionally, by exploiting the increased accuracy of the RK method's gradient, we formulate a simple limiter for the artificial viscosity that reduces the excess diffusion normally incurred by the ordinary SPH artificial viscosity. Collectively, we call our suite of modifications to the traditional SPH scheme Conservative Reproducing Kernel SPH, or CRKSPH. CRKSPH retains many benefits of traditional SPH methods (such as preserving Galilean invariance and manifest conservation of mass, momentum, and energy) while improving on many of the shortcomings of SPH, particularly the overly aggressive artificial viscosity and zeroth-order inaccuracy. We compare CRKSPH to two different modern SPH formulations (pressure based SPH and compatibly differenced SPH), demonstrating the advantages of our new formulation when modeling fluid mixing, strong shock, and adiabatic phenomena.
Mobile Internet life in Smart Korea
Creators: name: Song, Hung
Publisher: name: Swinburne
Year: 2024

description: Korea has been a leader in Information and Communications Technology (ICT) development for many years. Under the national catch phrase, 'IT Korea', the IT industry has driven the Korean economic growth and competitiveness. Now Korea is driving the IT industry into higher levels, towards 'Smart Korea'. This paper describes how Korea is transforming itself from an IT economy to a smart economy by expanding ICT capabilities to every aspect of people's lives. Also discussed are social and market trends and applications and services development driven by mobile Internet capabilities with smart devices, such as smartphones, smart tabs, and smart TVs.
An empirical study of the consistency of differential item functioning detection.
Creators: name: Brown, Paulette C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Education, Tests and Measurements.

description: Total test scores of examinees on any given standardized test are used to provide reliable and objective information regarding the overall performance of the test takers. When the probability of successfully responding to a test item is not the same for examinees at the same ability levels, but from different groups, the item functions differentially in favour of one group over the other group. This type of problem, defined as differential item functioning (DIF), creates a disadvantage for members of certain subgroups of test takers. Test items need to be accurate and valid measures for all groups because test results may be used to make significant decisions which may have an impact on the future opportunities available to test takers. Thus, DIF is an issue of concern in the field of educational measurement. The purpose of this study was to investigate how well the Mantel-Haenszel (MH) and logistic regression (LR) procedures perform in the identification of items that function differentially across gender groups and regional groups. Research questions to be answered by this study were concerned with three issues: (1) the detection rates for DIF items and items which did not exhibit DIF, (2) the agreement for the MH and LR methods in the detection of DIF items, and (3) the effectiveness of these indices across sample size and over replications. (Abstract shortened by UMI.)
Discourse with Visual Health Data: Design of Human-Data Interaction
Creators: name: Ola, Oluwakemi
name: Sedig, Kamran
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Previous work has suggested that large repositories of data can revolutionize healthcare activities; however, there remains a disconnection between data collection and its effective usage. The way in which users interact with data strongly impacts their ability to not only complete tasks but also capitalize on the purported benefits of such data. Interactive visualizations can provide a means by which many data-driven tasks can be performed. Recent surveys, however, suggest that many visualizations mostly enable users to perform simple manipulations, thus limiting their ability to complete tasks. Researchers have called for tools that allow for richer discourse with data. Nonetheless, systematic design of human-data interaction for visualization tools is a non-trivial task. It requires taking into consideration a myriad of issues. Creation of visualization tools that incorporate rich human-data discourse would benefit from the use of design frameworks. In this paper, we examine and present a design process that is based on a conceptual human-data interaction framework. We discuss and describe the design of interaction for a visualization tool intended for sensemaking of public health data. We demonstrate the utility of systematic interaction design in two ways. First, we use scenarios to highlight how our design approach supports a rich and meaningful discourse with data. Second, we present results from a study that details how users were able to perform various tasks with health data and learn about global health trends.
Supplemental material. Pediatric Lateral Distal Femur Reference Ranges for Ages 1 to 18 years.
Creators: name: Zemel, Babette
name: Shepherd, John
name: Kazemi, Laila
name: Kelly, Andrea
name: Stallings, Virginia A.
name: Kecskemethy, Heidi
name: weber, david
name: Wasserman, Halley
name: Kalkwarf, Heidi
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 321301
subject: Adolescent health
classificationCode: 321302
subject: Infant and child health

description: Supplemental material - lateral distal femur analysis procedure
Planen im Klimawandel
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2015

description: Der Klimawandel kommt nicht vielleicht. Er ist längst da. Diese Broschüre zeigt, wie er sich bereits heute vor Ort auswirkt, welche Aufgaben sich vor Ort als dringlich erweisen können und welche Anpassungsmaßnahmen und -strategien möglich und sogar bereits in der Praxis erprobt sind.
Quelle: Verlagsinformation
3956007.pdf
Creators: name: Banerji, Sourangsu
name: Meem, Monjurul
name: Majumder, Apratim
name: Guevara, Fernando Vasquez
name: Sensale-Rodriguez, Berardi
name: Menon, Rajesh
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Information
title: The dark side of text classification
title: addressing the negative aspects plaguing text classifiers
titleType: Subtitle
Creators: name: Rusert, Jonathan
Publisher: name: University of Iowa
Year: 2022
Subjects: Adversarial Attacks
Bias
Defense
Obfuscation
Text Classification
public abstract

description: Text classification is a well explored area, and can achieve strong results on manytasks. However, there are areas which are still problematic and need to be further explored and improved. Text classifiers are vulnerable to adversarial attacks so strong defenses are needed. Furthermore, text classifiers can be used by bad actors to harm privacy and freedoms, thus strong identity obfuscation algorithms are also needed. Finally, text classifiers have been found to unknowingly show bias against minority communities, thus strong bias detection and mitigation algorithms are need as well. In this thesis, we describe and motivate these problems and present new methods for their solution. Specifically, we present a new defense against adversarial attacks which is simple but effective in mitigating adversarial attacks. We present ways to compare and combine this defense with other state-of-the-art (SOTA) text classifier defenses as well as address the flaws of attacks exposed by the defense. Next we present a new obfuscation methodology which leverages humans’ craftiness to bypass censorship systems. Third, we present a community focused methodology to identify bias in text classifiers and datasets. Together these three contributions start to address the noted problems with text classification and open the door for future investigations and improvements of these areas.
Lack of netrin-4 modulates pathologic neovascularization in the eye
Creators: name: Kociok, Norbert
name: Crespo-Garcia, Sergio
name: Liang, Yong
name: Klein, Sabrina V.
name: Nürnberg, Christina
name: Reichhart, Nadine
name: Skosyrski, Sergej
name: Moritz, Eva
name: Maier, Anna-Karina
name: Brunken, William J.
name: Strauß, Olaf
name: Koch, Manuel
name: Joussen, Antonia M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Netrins are a family of matrix-binding proteins that function as guidance signals. Netrin-4 displays pathologic roles in tumorigenesis and neovascularization. To answer the question whether netrin-4 acts either pro- or anti-angiogenic, angiogenesis in the retina was assessed in Ntn-4−/− mice with oxygen-induced retinopathy (OIR) and laser-induced choroidal neovascularization (CNV), mimicking hypoxia-mediated neovascularization and inflammatory mediated angiogenesis. The basement membrane protein netrin-4 was found to be localised to mature retinal blood vessels. Netrin-4, but not netrin-1 mRNA expression, increased in response to relative hypoxia and recovered to normal levels at the end of blood vessel formation. No changes in the retina were found in normoxic Ntn-4−/− mice. In OIR, Ntn-4−/− mice initially displayed larger avascular areas which recovered faster to revascularization. Ganzfeld electroretinography showed faster recovery of retinal function in Ntn-4−/− mice. Expression of netrin receptors, Unc5H2 (Unc-5 homolog B, C. elegans) and DCC (deleted in colorectal carcinoma), was found in Müller cells and astrocytes. Laser-induced neovascularization in Nnt-4−/− mice did not differ to that in the controls. Our results indicate a role for netrin-4 as an angiogenesis modulating factor in O2-dependent vascular homeostasis while being less important during normal retinal developmental angiogenesis or during inflammatory neovascularization.
Selection bias in dynamically measured supermassive black hole samples: Its consequences and the quest for the most fundamental relation
Creators: name: Shankar, Francesco
name: Bernardi, Mariangela
name: Sheth, Ravi K.
name: Ferrarese, Laura
name: Graham, Alister
name: Savorgnan, Giulia
name: Allevato, Viola
name: Marconi, Alessandro
name: Läsker, Ronald
name: Lapi, Andrea
Publisher: name: Swinburne
Year: 2024

description: We compare the set of local galaxies having dynamically measured black holes with a large, unbiased sample of galaxies extracted from the Sloan Digital Sky Survey. We confirm earlier work showing that the majority of black hole hosts have significantly higher velocity dispersions σ than local galaxies of similar stellar mass. We use Monte-Carlo simulations to illustrate the effect on black hole scaling relations if this bias arises from the requirement that the black hole sphere of influence must be resolved to measure black hole masses with spatially resolved kinematics. We find that this selection effect artificially increases the normalization of the Mbh-σ relation by a factor of at least ∼3; the bias for the Mbh-Mstar relation is even larger. Our Monte Carlo simulations and analysis of the residuals from scaling relations both indicate that σ is more fundamental than Mstar or effective radius. In particular, the Mbh-Mstar relation is mostly a consequence of the Mbh-σ and σ-Mstar relations, and is heavily biased by up to a factor of 50 at small masses. This helps resolve the discrepancy between dynamically-based black hole-galaxy scaling relations versus those of active galaxies. Our simulations also disfavour broad distributions of black hole masses at fixed σ. Correcting for this bias suggests that the calibration factor used to estimate black hole masses in active galaxies should be reduced to values of fvir ∼ 1. Black hole mass densities should also be proportionally smaller, perhaps implying significantly higher radiative efficiencies/black hole spins. Reducing black hole masses also reduces the gravitational wave signal expected from black hole mergers.
"UFQ" ROMANIDAGI "QOCHOQ" NOMLI PARCHASI ASOSIDA MUHOKAMALI, MUNOZARALI YONDASHUV YOʻLLARINI ISHLAB CHIQISH
Creators: name: Saydullayeva, Shoira
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada “Ufq” romanidan joy olgan “Qochoq” nomli parchasini o‘qitish va tahlil qilish bo‘yicha muhokamali, munozarali yondashuv yo‘llari ishlab chiqilgan. Gardner nazariyasi asosida topshiriqlar tayyorlangan.
A Practical Quantum Algorithm for the Schur Transform
Creators: name: Kirby, William M.
name: Strauch, Frederick W.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We describe an efficient quantum algorithm for the quantum Schur transform. The Schur transform is an operation on a quantum computer that maps the standard computational basis to a basis composed of irreducible representations of the unitary and symmetric groups. We simplify and extend the algorithm of Bacon, Chuang, and Harrow, and provide a new practical construction as well as sharp theoretical and practical analyses. Our algorithm decomposes the Schur transform on $n$ qubits into $O\left(n^4\log\left(\frac{n}ε\right)\right)$ operators in the Clifford+T fault-tolerant gate set and uses exactly $2\lfloor\log_2(n)\rfloor-1$ ancillary qubits. We extend our qubit algorithm to decompose the Schur transform on $n$ qudits of dimension $d$ into $O\left(n^{d^2+2}\log^p\left(\frac{n^{d^2+1}}ε\right)\right)$ primitive operators from any universal gate set, for $p\approx3.97$.
description: Errata: older versions contained an incorrect analysis of a prior work, which is in fact superior in runtime scaling compared to the construction in this paper. See pdf for details. This analysis has been corrected, and a detailed errata is highlighted on the first page
A spectroscopic measure of the star formation rate density in dwarf galaxies at z ~ 1
Creators: name: Davies, G. T.
name: Gilbank, David G.
name: Glazebrook, Karl
name: Bower, Richard G.
name: Baldry, I. K.
name: Balogh, Michael L.
name: Hau, G. K.T.
name: Li, I. H.
name: McCarthy, P.
name: Savaglio, S.
Publisher: name: Swinburne
Year: 2024

description: We use a K-selected (22.5 < K-AB < 24.0) sample of dwarf galaxies (8.4 < log(M-*/M-circle dot) < 10) at 0.89 < z < 1.15 in the Chandra Deep Field-South to measure their contribution to the global star formation rate density (SFRD), as inferred from their [O II] flux. By comparing with [O II]-based studies of higher stellar mass galaxies, we robustly measure a turnover in the [O II] luminosity density at a stellar mass of M similar to 10(10) M-circle dot. By comparison with the [O II]-based SFRD measured from the Sloan Digital Sky Survey we confirm that, while the SFRD of the lowest mass galaxies changes very little with time, the SFRD of more massive galaxies evolves strongly, such that they dominate the SFRD at z = 1.
title: MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4
title: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients
titleType: Subtitle
Creators: name: Pache, Florence
name: Zimmermann, Hanna
name: Mikolajczak, Janine
name: Schumacher, Sophie
name: Lacheta, Anna
name: Oertel, Frederike C. [U.V.M.]
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG)
subject: aquaporin-4 antibodies (AQP4-IgG)
subject: NMO-IgG
subject: neuromyelitis optica
subject: Devic syndrome
subject: neuromyelitis optica spectrum disorders (NMOSD)
subject: optic neuritis
subject: optical coherence tomography
subject: visual evoked potentials
subject: visual acuity
subject: retinal neuro-axonal damage
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with aquaporin-4 antibody (AQP4-IgG)-negative neuromyelitis optica spectrum disorders (NMOSD). The objective of this study was to describe optic neuritis (ON)-induced neuro-axonal damage in the retina of MOG-IgG-positive patients in comparison with AQP4-IgG-positive NMOSD patients. Methods Afferent visual system damage following ON was bilaterally assessed in 16 MOG-IgG-positive patients with a history of ON and compared with that in 16 AQP4-IgG-positive NMOSD patients. In addition, 16 healthy controls matched for age, sex, and disease duration were analyzed. Study data included ON history, retinal optical coherence tomography, visual acuity, and visual evoked potentials. Results Eight MOG-IgG-positive patients had a previous diagnosis of AQP4-IgG-negative NMOSD with ON and myelitis, and eight of (mainly recurrent) ON. Twenty-nine of the 32 eyes of the MOG-IgG-positive patients had been affected by at least one episode of ON. Peripapillary retinal nerve fiber layer thickness (pRNFL) and ganglion cell and inner plexiform layer volume (GCIP) were significantly reduced in ON eyes of MOG- IgG-positive patients (pRNFL = 59 ± 23 μm; GCIP = 1.50 ± 0.34 mm3) compared with healthy controls (pRNFL = 99 ± 6 μm, p
3956007.pdf
Creators: name: Banerji, Sourangsu
name: Meem, Monjurul
name: Majumder, Apratim
name: Guevara, Fernando Vasquez
name: Sensale-Rodriguez, Berardi
name: Menon, Rajesh
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Uncategorized

description: Supplementary Information
Computer techniques for electromagnetic interaction modelling.
Creators: name: LoVetri, Joseph (Joe).
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1991
Subjects: subject: Engineering, Electronics and Electrical.

description: Computer techniques for the modelling of complex electromagnetic interactions are explored. The main thesis is that these techniques, or methods, can be divided into two types: non-algorithmic and algorithmic techniques. Approximate algorithmic methods for the modelling of electromagnetic interactions have undergone great advances in the past twenty years but they are still only feasible for relatively small problems (i.e. where the space-time discretization produces and requires only a relatively small number of unknowns). The computer implementation of non-algorithmic methods have recently become a reality with the maturing of expert system technology and knowledge based engineering. In Part I of this thesis, a knowledge-based approach for the modelling of electromagnetic (EM) interactions in a system is described. The purpose is to determine any unwanted EM effects which could jeopardize the safety and operation of the system. Modelling the interactions in a system requires the examination of the compounded and propagated effects of the electromagnetic fields. A useful EM modelling approach is one which is incremental and constraint-based. The approach taken here subdivides the modelling task into two parts: (a) the definition of the related physical topology, and (b) the propagation of the electromagnetic constraints. A prototype of some of the EM constraints has been implemented in Quintus Prolog under NeWS on a Sun workstation. User interaction is through a topology drawing tool and a stack-based attribute interface similar to the HyperCard$\sp{\rm TM}$ interface of the Apple Macintosh computer. In Part II, numerical methods which discretize the space-time region of interest and provide a solution to the electromagnetics problem, given appropriate initial and boundary conditions, are investigated. Specifically, time-domain finite difference methods as applied to Maxwell's equations are analyzed, compared and implemented. As the basis of this analysis, Maxwell's equations are expressed as a system of hyperbolic conservation laws. Analytical properties of these systems, based on the method of characteristics, are used to study the numerical solution of Maxwell's equations. Practical issues, such as computational efficiency and memory requirements, are discussed for the implementation of the finite difference schemes. Advanced programming techniques are used to implement all the finite difference schemes discussed. The schemes are used to solve the problem of the penetration of electromagnetic energy through a shield with a thick gap. A two-dimensional time-domain finite element method, implemented as the software package PDE/PROTRAN, is also applied to shielding problems. The software package is first validated for simple hyperbolic problems and is then applied to perfectly conducting shields with apertures.
Wireless broadband developments in Australia - an industry perspective
Creators: name: Althaus, Chris
Publisher: name: Swinburne
Year: 2024

description: Rapid consumer adoption of mobile devices is driving increased data traffic as consumers seek to utilise a range of applications and services, including mobile broadband, emails, videos, social networking, online banking and shopping. This paper explores the rapidly growing demand for latest generation mobile data applications and services, particularly mobile broadband, from a mobile telecommunications industry perspective. Mobile data traffic is forecast to increase at a compound annual growth of 95 per cent to 2014. Mobile telecommunications plays a key productivity-enabling role in the digital economy. Mobile operators must have access to sufficient radiofrequency spectrum and be able to deploy network infrastructure (base stations and towers) efficiently if they are to meet consumer demand. AMTA strongly believes Government policy must encourage continued investment in infrastructure and innovation to ensure that the benefits of mobile broadband and a growing digital economy can be realised by all Australians.
Utilizing weight bearing CT to explore predictors of post-traumatic osteoarthritis risk after tibial pilon fracture
Creators: name: Miller, Tristan
Publisher: name: University of Iowa
Year: 2024

description: Post-traumatic osteoarthritis (PTOA) is a painful joint condition that occurs years after traumatic injury. Injuries to joints of the lower extremity most commonly result in PTOA, affecting over 5 million people in the United States alone. Characteristics of the condition include joint pain, stiffness, and functional limitations, as well as decreases in sleep quality and mental health. In the ankle joint specifically, compressive fractures of the distal tibia, or pilon fractures, provide opportunities to learn more about how the disease progresses, as these injuries result in high rates of PTOA development within a timeframe of 2-3 years.
description: By identifying early signs of PTOA, advancements can be made in testing new clinical treatments aimed at mitigating PTOA risk. Therefore, the goal of this project was to improve early detection of PTOA development by exploring relationships between variables used to quantify joint health and later indications of PTOA.
description: Previously developed computational modeling approaches were utilized to determine injury-specific fracture energy, to measure joint space width, and to estimate chronic contact stress exposure from pre-operative CT and post-operative weight bearing CT images. Modifications made to these modeling approaches improved JSW measurement accuracy and established the repeatability of these measurement techniques. Relationships were found between early classification metrics and subsequent joint changes indicative of PTOA that provide a basis for more reliable early detection of PTOA.
CREATING EFFECTIVE REDUNDANCY ALLOCATION SYSTEMS FOR ENHANCED RELIABILITY
Creators: name: Marcus, Alexander Johnson
Publisher: name: CARSON JOURNAL
Year: 2024
Subjects: redundancy allocation, reliability, optimization models, complex systems, resource constraints

description: NASA defines redundancy as the use of multiple independent means to achieve a task, a critical aspect of ensuring mission success and system reliability. This concept was exemplified during NASA's Apollo 10 mission, where the availability of redundant systems allowed the mission to continue when faced with technical challenges. However, in the design of complex systems, achieving high levels of redundancy to meet stringent reliability goals can introduce challenges related to cost, weight, and size constraints. Balancing these trade-offs can be a complex task, as optimization models for redundancy allocation may be challenging to solve, as noted by Chern in 1992. Nevertheless, Chern also identified specific redundancy allocation models that can be solved efficiently within polynomial time. This research explores the optimization of redundancy allocation in complex systems, aiming to strike a balance between reliability goals and resource constraints. By leveraging the models identified by Chern, this study offers insights into effective redundancy allocation strategies to enhance system reliability while considering practical limitations.
Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p
Creators: name: Wotschofsky, Zofia
name: Gummlich, Linda
name: Liep, Julia
name: Stephan, Carsten
name: Kilic, Ergin
name: Jung, Klaus
name: Billaud, Jean-Noel
name: Meyer, Hellmuth-Alexander
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016

description: Background MicroRNAs (miRNAs) regulate gene expression by interfering translation or stability of target transcripts. This interplay between miRNA and their mRNA has been proposed as an important process in cancer development and progression. We have investigated molecular networks impacted by predicted mRNA targets of differentially expressed miRNAs in patients with clear cell renal cell carcinoma (ccRCC) diagnosed with or without metastasis. Material and Methods miRNA and mRNA microarray expression profiles derived from primary ccRCC from patients with (16 samples) or without diagnosed metastasis (22 samples) were used to identify anti-correlated miRNA-mRNA interaction in ccRCC. For this purpose, Ingenuity pathway analysis microRNA Target Filter, which enables prioritization of experimentally validated and predicted mRNA targets was used. By applying an expression pairing tool, the analysis was focused on targets exhibiting altered expression in our analysis, finding miRNAs and their target genes with opposite or same expression. The resulting identified interactions were revalidated by RT-qPCR in another cohort of ccRCC patients. A selection of the predicted miRNA-mRNA interactions was tested by functional analyses using miRNA knockdown and overexpression experiments in renal cancer cell lines. Results Among the significantly differentially expressed miRNAs, we have identified three miRNAs (miR-146a-5p, miR-128a-3p, and miR-17-5p) that were upregulated in primary tumors from patients without metastasis and downregulated in primary tumors from patients with metastasis. We have further identified mRNA targets, which expression were inversely correlated to these 3 miRNAs, and have been previously experimentally demonstrated in cancer setting in humans. Specifically, we showed that CXCL8/IL8, UHRF1, MCM10, and CDKN3 were downregulated and targeted by miR- 146a-5p. The interaction between miR-146a-5p and their targets CXCL8 and UHRF1 was validated in cell culture experiments. Conclusions We identified novel target genes of dysregulated miRNAs, which are involved in the transition from primary RCC without metastases into tumors generating distant metastasis.
title: Weichmacherverlust bei PVC-Objekten von Joseph Beuys
title: Versuche zu kurativen und konservatorischen Massnahmen
titleType: Subtitle
Creators: name: Ryf, Sandra
Publisher: name: Hochschule der Künste Bern
Year: 2006
Subjects: Conservation

description: Bei Multiples von Joseph Beuys aus Weich-PVC-Material der frühen Siebziger Jahre zeigt sich seit einigen Jahren eine massive Auswanderung von Weichmacher. In der vorliegenden Arbeit werden die Ergebnisse von drei verschiedenen Strategien konservierungstechnischer Eingriffe dokumentiert: chemische Nachstabilisierung, Beschichtung sowie trockene Reinigung der Oberfläche. Dank der Witwe von Joseph Beuys konnten die Versuche an Originalmaterial (unsignierte Ausschuss-Multiples) durchgeführt werden. Frühere Untersuchungen haben gezeigt, dass die Antriebsmechanismen der Entmischung primär in der Hydrolyse des Weichmachers, eines Polyesteradipats, zu suchen sind. Der Schwerpunkt des experimentellen Teils lag deshalb auf Versuchen zur chemischen Nachstabilisierung des Materials durch Immersion in Lösungen mit Hydrolyseschutzmitteln. Die Diffusionsfähigkeit und Wirksamkeit der dazu verwendeten Carbodiimide für das vorliegende Material wurde mittels verschiedener apparativer Methoden untersucht. Die Resultate ließen auf die Möglichkeit einer gewissen Stabilisierungswirkung schließen, jedoch zeigten sich auch nachteilige Effekte. Versuchsreihen zur Reinigung führten zum Ergebnis, dass ein wiederholtes Entfernen des Weichmachers von der Oberfläche beim vorliegenden Material keine Veränderung der Auswanderungsrate zur Folge hat. Die Beschichtung mit einem Zweikomponentenlack auf Acrylbasis zeigte, dass ein geeignetes Überzugsmittel die Hydrolyseprozesse durch Behindern des Zutritts von Feuchtigkeit verzögern kann.
Stationary dense operators in sequentially complete locally convex spaces
Creators: name: Kostić, Marko
name: Pilipović, Stevan
name: Velinov, Daniel
Publisher: name: arXiv
Year: 2018
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 35R11, 45D05, 45N05, 47D99

description: The purpose of this paper is to investigate the stationary dense operators and their connection to distribution semigroups and abstract Cauchy problem in sequentially complete spaces.
description: arXiv admin note: substantial text overlap with arXiv:1610.02791
Una fiesta palaciega de finales del siglo XVII: "Hado y divisa de Leonido y de Marfisa", de Pedro Calderon de la Barca
Creators: name: Sanchez-Velo, Julio M
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Language, Modern.
subject: Literature, Romance.
subject: Theater.

description: This study is a critical edition with an introduction and notes of Hado y divisa de Leonido y de Marfisa, the last creation of one of the most influential playwrights of all time, D. Pedro Calderon de la Barca (1600-1681). This is an eclectic edition based on a manuscript with signature MS. 8314 from L'Arsenal Library in Paris, corrected and modified when deemed necessary with the help of other existing textual witnesses. The introduction includes an analysis of the political, social and economic context of this comedia and the circumstances of its production; the literary context and characteristics that it shares with the byzantine and chivalry novels; its textual transmission; its musical tradition; its staging and its polymetrical structure. At the end of this study are included the explanatory notes as well as the textual variants of all witnesses analyzed.
title: Methodenkonvention 3.0 zur Ermittlung von Umweltkosten
title: Methodenkonvention 3.0 zur Ermittlung von Umweltkosten
titleType: AlternativeTitle
Creators: name: Bünger, Björn
name: Matthey, Astrid
Publisher: name: Umweltbundesamt
Year: 2019
Subjects: Umweltschutzkosten
Gesetzesfolgenabschätzung

description: Die Methodenkonvention 3.0 zur Ermittlung von Umweltkosten enthält Empfehlungen für Methoden zur Ermittlung von Umweltkosten (Teil "Methodische Grundlagen") sowie neue Kostensätze zu den Themen Treibhausgase, Luftschadstoffe, Lärm, Verkehr und Energie (Teil "Kostensätze"). Die Kostensätze machen deutlich, welchen Nutzen Umweltschutz für die Gesellschaft hat und, welche Kosten der Gesellschaft durch unterlassenem Umweltschutz entstehen. Sie ermöglichen eine bessere Abschätzung der Folgen von gesetzlichen Regelungen und öffentlichen Investitionen sowie der Ausgestaltung von ökonomischen Instrumenten. In Unternehmen können sie u. a. verwendet werden, um die Umweltkosten von Produkten zu bestimmen und die Nachhaltigkeitsberichterstattung zu ergänzen. Quelle: https://www.umweltbundesamt.de
Innervation in tissue engineered corneal equivalents
Creators: name: Suuronen, Erik
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Health Sciences, Ophthalmology.

description: A sensory nerve supply is crucial for optimal function of the cornea. However, the mechanisms for successful innervation and the signalling pathways between nerves and their target tissue are not fully understood. Engineered tissue substitutes can provide controllable environments in which to study tissue innervation. I have therefore engineered human corneal substitutes that promote nerve in-growth in a pattern similar to in vivo re-innervation. The methodology developed for the fabrication of such an innervated model cornea and for subsequent investigation of the function of these nerves is discussed in this thesis. Briefly, nerve in-growth into the tissue-engineered cornea is enhanced by the addition of laminin and nerve growth factor, but not retinoic acid. I demonstrated that these nerves are morphologically equivalent to natural corneal nerves and make appropriate contact with their target cells, which consequently, were found to be required for their survival. The nerves had functional sodium channels and generated action potentials similar to those of native nerve endings. I also demonstrated that the nerves could respond appropriately to chemical and physical stimuli and play an important role in the overall functioning of the bioengineered tissue. The presence of nerves conferred some protection to the epithelium from chemical insult and differential retention of sodium was observed within the nerve fibres themselves. As such, this model could be further developed for use as an in vitro alternative to animals for safety and efficacy testing of chemicals and drugs. Based on the concepts developed for these in vitro innervated corneas, hybrid biosynthetic matrices with the proper dimensions, transparency and biomechanical properties for use as corneal replacements in transplantation were also developed. These matrices were successfully implanted into corneas of pigs. Regeneration of corneal tissue and nerves was observed, along with restoration of sensory function. The basic model developed therefore can be used for studying corneal wound healing, nerve-corneal cell interactions and provides a basis for developing corneal replacements for transplantation.
3961300.pdf
Creators: name: Jiang, Wentao
name: Patel, Rishi
name: Mayor, Felix
name: McKenna, Timothy
name: Arriola, Patricio Arrangoiz
name: Sarabalis, Christopher
name: Witmer, J.
name: Van Laer, Raphaël
name: Safavi-Naeini, Amir
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
The electron self-energy in QED at two loops revisited
Creators: name: Hönemann, Ina
name: Tempest, Kirsten
name: Weinzierl, Stefan
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We reconsider the two-loop electron self-energy in quantum electrodynamics. We present a modern calculation, where all relevant two-loop integrals are expressed in terms of iterated integrals of modular forms. As boundary points of the iterated integrals we consider the four cases $p^2=0$, $p^2=m^2$, $p^2=9m^2$ and $p^2=\infty$. The iterated integrals have $q$-expansions, which can be used for the numerical evaluation. We show that a truncation of the $q$-series to order ${\mathcal O}(q^{30})$ gives numerically for the finite part of the self-energy a relative precision better than $10^{-20}$ for all real values $p^2/m^2$.
description: 45 pages, v2: version to be published, v3: eq.(40) and (41) corrected
Stretch the edge. International case studies data collection questionnaire.
Creators: name: Gasparotto, Silvia
name: DALL'OSSO, GIORGIO
name: Rosati, Federica Natalia
name: Amatori, Chiara
Publisher: name: Zenodo
Year: 2024

description: The paper shows the questions contained in the questionnaire used for data collection regarding the international symposium "Stretch the Edge. Design driven processes for reactivating small walled towns and inland areas" (https://stretchtheedge.unirsm.sm/).

The questionnaire was administered through a google form.
On feature point matching, in the calibrated and uncalibrated contexts, between widely and narrowly separated images
Creators: name: Vincent, Etienne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2004
Subjects: subject: Computer Science.

description: In this work, the correspondence problem for feature points between images is investigated. In this context, two important factors greatly influence the choice of a strategy: whether the camera system is calibrated or not, and how large is the separation between viewpoints. This work is divided into four parts, for the four important matching situations generated by these two factors. In the case of uncalibrated narrowly separated views, a framework for empirically evaluating matching constraints is presented. Then, various new and existing constraints are compared. In the case of calibrated narrowly separated views, a new type of feature is introduced, epipolar gradient features. These are then shown to be especially appropriate for matching in the context of quick reconstruction. The features are then matched with a new constraint based on trinocular line transfer. In the case of uncalibrated widely separated views, it is shown how the shape of feature points can be used to recover local perspective deformation between two views, and improve matching results. To this end, a new corner detector that generates the required information is also introduced. In the case of calibrated widely separated views, a more accurate estimate of local perspective deformation is obtained by incorporating the knowledge of the epipolar geometry. An application to fundamental matrix estimation is also introduced.
Where wireless broadband makes sense
Creators: name: Ayre, Rob
name: Cheong, Jeff
name: Cornick, Kate
name: Gathercole, Brad
name: Hinton, Kerry
name: Lodders, Adam
name: Tucker, Rod
Publisher: name: Swinburne
Year: 2024

description: This paper shows that in order to meet forecast user data demands using a fixed wireless broadband network in suburban and inner urban environments, a high density of base stations would be required. This in turn requires the development of a backhaul network to interconnect the base stations comparable in scale to a fibre to the premises (FTTP) network. To achieve an increase in the capacity of wireless networks to serve densely populated areas would require more spectrum than is available from the entire 'Digital Dividend' allocation, and the number of base stations needed to be installed would substantially exceed those used for today's mobile wireless networks. However fixed wireless broadband presents a feasible approach for other less densely populated areas.
3961300.pdf
Creators: name: Jiang, Wentao
name: Patel, Rishi
name: Mayor, Felix
name: McKenna, Timothy
name: Arriola, Patricio Arrangoiz
name: Sarabalis, Christopher
name: Witmer, J.
name: Van Laer, Raphaël
name: Safavi-Naeini, Amir
Publisher: name: Optica Publishing Group
Year: 2019
Subjects: Uncategorized

description: Supplemental Document
The WiggleZ Dark Energy Survey: Small-scale clustering of Lyman-break galaxies at z 1
Creators: name: Blake, Chris
name: Jurek, Russell J.
name: Brough, Sarah
name: Colless, Matthew
name: Couch, Warrick
name: Croom, Scott
name: Davis, Tamara
name: Drinkwater, Michael J.
name: Forbes, Duncan
name: Glazebrook, Karl
name: Madore, Barry
name: Martin, Chris
name: Pimbblet, Kevin
name: Poole, Gregory B.
name: Pracy, Michael
name: Sharp, Rob
name: Small, Todd
name: Woods, David
Publisher: name: Swinburne
Year: 2024

description: The WiggleZ Dark Energy Survey is a large-scale structure survey of intermediate-redshift ultraviolet-selected (UV-selected) emission-line galaxies scheduled to cover 1000 deg2, spanning a broad redshift range 0.2 < z < 1.0 . The main scientific goal of the survey is the measurement of baryon acoustic oscillations (BAO) in the galaxy clustering pattern at a significantly higher redshift than previous studies. The BAO may be applied as a standard cosmological ruler to constrain dark energy models. Based on the first 20 per cent of the data set, we present initial results concerning the small-scale clustering of the WiggleZ targets, together with survey forecasts. The WiggleZ galaxy population possesses a clustering length r0= 4.40 ± 0.12 h−1 Mpc, which is significantly larger than z= 0 UV-selected samples, with a slope γ= 1.92 ± 0.08 . This clustering length is comparable to z= 3 Lyman-break galaxies with similar UV luminosities. The clustering strength of the sample increases with optical luminosity, UV luminosity and reddening rest-frame colour. The full survey, scheduled for completion in 2010, will map an effective volume Veff≈ 1 Gpc3 (evaluated at a scale k= 0.15 h Mpc−1 ) and will measure the angular diameter distance and Hubble expansion rates in three redshift bins with accuracies of ≈5 per cent. We will determine the value of a constant dark energy equation-of-state parameter, wcons, with a higher precision than existing supernovae observations using an entirely independent technique. The WiggleZ and supernova measurements lie in highly complementary directions in the plane of wcons and the matter density Ωm. The forecast using the full combination of WiggleZ, supernova and cosmic microwave background (CMB) data sets is a marginalized error Δwcons= 0.07 , providing a robust and precise measurement of the properties of dark energy including cross-checking of systematic errors.
Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols
Creators: name: Weber, Patrick
name: Nasseri, Seyed A.
name: Pabst, Bettina M.
name: Torvisco, Ana
name: Müller, Philipp
name: Paschke, Eduard
name: Tschernutter, Marion
name: Windischhofer, Werner
name: Withers, Stephen G.
name: Wrodnigg, Tanja M.
name: Stütz, Arnold E.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: From 1,2;3,4-di-O-isopropylidene-d-galactopyranose, a preliminary series of highly functionalized amino(hydroxymethyl)cyclopentanes was easily available. These amine-containing basic carbasugars featuring the d-galacto configuration are potent inhibitors of the GH20 β-d-hexosaminidases probed and may bear potential as regulators of N-acetyl-d-hexosaminidase activities in vivo.
El español como L2 en contextos de aprendizaje institucional : la adquisición de los pronombres átonos.
Creators: name: Maxwell, Denyse.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Education, Bilingual and Multicultural.

description: We have analyzed the spontaneous oral production of a group of adolescent and adult native French, English and bilingual students in the initial stages of contact with Spanish as a second language in classroom settings in order to determine what role age, learning context and previous linguistic experience, i.e. the mother tongue or other second languages, have on the acquisition of unstressed pronouns. Moreover, it has been our intention to determine the characteristics of these pronouns (or clitics) in the interlanguage (IL) of our subjects as well as to determine whether there is any difference between the non-native and native use of these pronouns. Specifically, we have analyzed the order of acquisition, the morphology, and the value of the reflexive, experiential, and object pronouns in the IL of our subjects. Our investigations confirm that (1) the subjects acquired some type of native-like system of clitics because native-like clitics were produced from the first interview; (2) as previous investigations have shown, it is the reflexive and experiential pronouns that are acquired first; (3) the subjects appear to value the clitics as affixes and not as nouns; (4) the differences between adolescent and adult acquisition cannot be clearly established; neither can (5) the correlation between the first and or other second language(s) and the acquisition of Spanish be determined at these initial stages. Further investigations at more advanced states of acquisition are required.
Design Justice Zine - The Algorithms of Trans Exclusion
Creators: name: Williams, Sagarika Jacqueline
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 460806
subject: Human-computer interaction

description: This zine is for the coursework INM317 Design Justice (PRD2 A 2024/25) and covers two technologies that invalidate and exclude the trans community.