cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Fully general relativistic simulations of rapidly rotating quark stars: Oscillation modes and universal relations
Creators: name: Chen, Kenneth
name: Lin, Lap-Ming
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: (Abridged) Numerical simulation of strange quark stars (QSs) is challenging due to the strong density discontinuity at the stellar surface. In this paper, we report successful simulations of rapidly rotating QSs and study their oscillation modes in full general relativity. Building on top of the numerical relativity code \texttt{Einstein Toolkit}, we implement a positivity-preserving Riemann solver and a dust-like atmosphere to handle the density discontinuity at the surface. We demonstrate the robustness of our numerical method by performing stable evolutions of rotating QSs close to the Keplerian limit and extracting their oscillation modes. We focus on the quadrupolar $l=|m|=2$ $f$-mode and study whether they can still satisfy the universal relations recently proposed for rotating neutron stars (NSs). We find that two of the three proposed relations can still be satisfied by rotating QSs. For the remaining broken relation, we propose a new relation to unify the NS and QS data by invoking the dimensionless spin parameter $j$. The onsets of secular instabilities for rotating QSs are also studied by analyzing the $f$-mode frequencies. Same as the result found previously for NSs, we find that QSs become unstable to the Chandrasekhar-Friedman-Schutz instability when the angular velocity of the star $Ω\approx 3.4 σ_0$ for sequences of constant central energy density, where $σ_0$ is the mode frequency of the corresponding nonrotating configurations. For the viscosity-driven instability, we find that QSs become unstable when $j\approx 0.881$ for both sequences of constant central energy density and constant baryon mass. Such a high value of $j$ cannot be achieved by realistic rotating NSs before reaching the Keplerian limit.
description: 22 pages, 20 figures
Formation of Warped Disks by Galactic Fly-by Encounters. I. Stellar Disks
Creators: name: Kim, Jeonghwan H.
name: Peirani, Sebastien
name: Kim, Sungsoo
name: Ann, Hong Bae
name: An, Sung-Ho
name: Yoon, Suk-Jin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Warped disks are almost ubiquitous among spiral galaxies. Here we revisit and test the `fly-by scenario' of warp formation, in which impulsive encounters between galaxies are responsible for warped disks. Based on N-body simulations, we investigate the morphological and kinematical evolution of the stellar component of disks when galaxies undergo fly-by interactions with adjacent dark matter halos. We find that the so-called `S'-shaped warps can be excited by fly-bys and sustained for even up to a few billion years, and that this scenario provides a cohesive explanation for several key observations. We show that disk warp properties are governed primarily by the following three parameters; (1) the impact parameter, i.e., the minimum distance between two halos, (2) the mass ratio between two halos, and (3) the incident angle of the fly-by perturber. The warp angle is tied up with all three parameters, yet the warp lifetime is particularly sensitive to the incident angle of the perturber. Interestingly, the modeled S-shaped warps are often non-symmetric depending on the incident angle. We speculate that the puzzling U- and L-shaped warps are geometrically superimposed S-types produced by successive fly-bys with different incident angles, including multiple interactions with a satellite on a highly elongated orbit.
description: 16 pages, 13 figures, 3 tables. Accepted for publication in ApJ
Bioburden after Staphylococcus aureus Inoculation in Type 1 Diabetic Rats Undergoing Internal Fixation
Creators: name: Cho, Eugenia H.
name: Klitzman, Bruce
name: Schoenfisch, Mark H.
name: Rose, Michael B.
name: Erdmann, Detlev
name: Brown, Nga L.
name: Blueschke, Gert
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Fracture stabilization in the diabetic patient is associated with higher complication rates, particularly infection and impaired wound healing, which can lead to major tissue damage, osteomyelitis, and higher amputation rates. With an increasing prevalence of diabetes and an aging population, the risks of infection of internal fixation devices are expected to grow. Although numerous retrospective clinical studies have identified a relationship between diabetes and infection, currently there are few animal models that have been used to investigate postoperative surgical site infections associated with internal fixator implantation and diabetes. We therefore refined the protocol for inducing hyperglycemia and compared the bacterial burden in controls to pharmacologically induced type-1 diabetic rats after undergoing internal fracture plate fixation and Staphylococcus aureus surgical site inoculation. Using an initial series of streptozotocin doses, followed by optional additional doses to reach a target blood glucose range of 300–600 mg/dl, we reliably induced diabetes in 100% of the rats (n=16) who maintained a narrow hyperglycemic range 14 days after onset of diabetes (466 ± 16 mg/dl, mean ± SEM; coefficient of variation = 0.15). With respect to our primary endpoint, we quantified a significantly higher infectious burden in inoculated diabetic animals (median 3.2 × 1010 CFU/mg dry tissue) when compared to inoculated non-diabetics (7.2 × 104 CFU/mg dry tissue). These data support our hypothesis that uncontrolled diabetes adversely affects the immune system’s ability to clear S. aureus associated with internal hardware.
Beyond Worst-Case Analysis for Root Isolation Algorithms
Creators: name: Ergür, Alperen A.
name: Tonelli-Cueto, Josué
name: Tsigaridas, Elias
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computational Complexity (cs.CC)
subject: Symbolic Computation (cs.SC)
subject: Algebraic Geometry (math.AG)
subject: Probability (math.PR)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: 65H04, 14Q20, 68W30

description: Isolating the real roots of univariate polynomials is a fundamental problem in symbolic computation and it is arguably one of the most important problems in computational mathematics. The problem has a long history decorated with numerous ingenious algorithms and furnishes an active area of research. However, the worst-case analysis of root-finding algorithms does not correlate with their practical performance. We develop a smoothed analysis framework for polynomials with integer coefficients to bridge the gap between the complexity estimates and the practical performance. In this setting, we derive that the expected bit complexity of DESCARTES solver to isolate the real roots of a polynomial, with coefficients uniformly distributed, is $\widetilde{\mathcal{O}}_B(d^2 + d τ)$, where $d$ is the degree of the polynomial and $τ$ the bitsize of the coefficients.
description: 9 pages, 2 figures. 2nd version: New title, corrections. 3rd version: Correction of typo in name
Simple cultural organisation system (SCOS) - an interoperable cultural taxonomy
Creators: name: Nevile, Liddy
name: Kateli, Behzad Aspi
name: Pulis, Sarah Terese
Publisher: name: La Trobe
Year: 2023

description: From an online publication.

['School of Engineering and Mathematical Sciences', 'Museums and the Web (2006 : Albuquerque, USA)']
Reconstructing quantum states from local data
Creators: name: Swingle, Brian
name: Kim, Isaac H.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider the problem of reconstructing global quantum states from local data. Because the reconstruction problem has many solutions in general, we consider the reconstructed state of maximum global entropy consistent with the local data. We show that unique ground states of local Hamiltonians are exactly reconstructed as the maximal entropy state. More generally, we show that if the state in question is a ground state of a local Hamiltonian with a degenerate space of locally indistinguishable ground states, then the maximal entropy state is close to the ground state projector. We also show that local reconstruction is possible for thermal states of local Hamiltonians. Finally, we discuss a procedure to certify that the reconstructed state is close to the true global state. We call the entropy of our reconstructed maximum entropy state the "reconstruction entropy", and we discuss its relation to emergent geometry in the context of holographic duality.
description: 4+2 pages
Nitrogen-tailored quasiparticle energy gaps of polyynes
Creators: name: Zhang, Kan
name: Li, Jiling
name: Liu, Peitao
name: Yang, Guowei
name: Shi, Lei
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Polyyne, a sp1-hybridized linear allotrope of carbon, has a tunable quasiparticle energy gap, which depends on the terminated chemical ending groups as well as the chain length. Previously, nitrogen doping was utilized to tailor the properties of different kinds of allotrope of carbon. However, how the nitrogen doping tailors the properties of the polyyne remains unexplored. Here, we applied the GW method to study the quasiparticle energy gaps of the N-doped polyynes with different lengths. When a C atom is substituted by a N atom in a polyyne, the quasiparticle energy gap varies with the substituted position in the polyyne. The modification is particularly pronounced when the second-nearest-neighboring carbon atom of a hydrogen atom is substituted. In addition, the nitrogen doping makes the Fermi level closer to the lowest unoccupied molecular orbital, resulting in a n-type semiconductor. Our results suggest another route to tailor the electronic properties of polyyne in addition to the length of polyyne and the terminated chemical ending groups.
description: 10 pages, 5 figures
Johann Sebastian Bach und Johann Friedrich Bach als Orgelexaminatoren im Gebiet der freien Reichsstadt Mühlhausen nach 1708
Creators: name: Kröhner, Christine
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Drei erstmals veröffentlichte Dokumente belegen, daß Johann Sebastian Bach mit größter Wahrscheinlichkeit 1712 zur Abnahme der von Johann Friedrich Wender erneuerten Orgel in Ammern weilte und daß Johann Friedrich Bach, sein Vetter und Amtsnachfolger als Organist in Mühlhausen, 1715 eine neue Orgel in Felchta examinierte und 1724 als Gutachter des von Johann Conrad Allstedt neu erbauten Orgelwerkes an St. Jacobi zu Mühlhausen mit herangezogen wurde. Im Text findet sich auch eine Liste der Orgeln in und um Mühlhausen, die Wender zwischen 1688 und 1722 errichtete, umbaute, erweiterte oder reparierte. (Autor, Quelle: Bibliographie des Musikschrifttums online)
description: Bach-Jahrbuch, Bd. 81 (1995)
Bilateral Mastectomy versus Breast-Conserving Surgery for Early-Stage Breast Cancer: The Role of Breast Reconstruction
Creators: name: Albornoz, Claudia R.
name: Elkin, Elena
name: Pusic, Andrea L.
name: Lee, Clara N.
name: Bach, Peter B.
name: Matros, Evan
name: Hudis, Clifford A.
name: Morrow, Monica
name: Cordeiro, Peter G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BACKGROUND: Although breast-conserving surgery is oncologically safe for women with early-stage breast cancer, mastectomy rates are increasing. The objective of this study was to examine the role of breast reconstruction in the surgical management of unilateral early-stage breast cancer.

METHODS: A retrospective cohort study of women diagnosed with unilateral early-stage breast cancer (1998 to 2011) identified in the National Cancer Data Base was conducted. Rates of breast-conserving surgery, unilateral and bilateral mastectomy with contralateral prophylactic procedures (per 1000 early-stage breast cancer cases) were measured in relation to breast reconstruction. The association between breast reconstruction and surgical treatment was evaluated using a multinomial logistic regression, controlling for patient and disease characteristics.

RESULTS: A total of 1,856,702 patients were included. Mastectomy rates decreased from 459 to 360 per 1000 from 1998 to 2005 (p < 0.01), increasing to 403 per 1000 in 2011 (p < 0.01). The mastectomy rates rise after 2005 reflects a 14 percent annual increase in contralateral prophylactic mastectomies (p < 0.01), as unilateral mastectomy rates did not change significantly. Each percentage point of increase in reconstruction rates was associated with a 7 percent increase in the probability of contralateral prophylactic mastectomies, with the greatest variation explained by young age(32 percent), breast reconstruction (29 percent), and stage 0 (5 percent).

CONCLUSIONS: Since 2005, an increasing proportion of early-stage breast cancer patients have chosen mastectomy instead of breast-conserving surgery. This trend reflects a shift toward bilateral mastectomy with contralateral prophylactic procedures that may be facilitated by breast reconstruction availability.
title: Quando ritorno ti porto un fiore [poster]
title: Canti e memorie di guerra
titleType: AlternativeTitle
Creators: name: Mascialino, Lavinia
name: De Donatis, Francesco
name: Licci, Emanuele
name: Resta, Matteo
name: Rutigliano, Giuseppe
name: Lorusso, Alessandro
Publisher: name: L. Mascialino et al., "Quando ritorno ti porto un fiore", in Anvedi che storia! VI Conferenza Nazionale AIPH. Dipartimento di Studi Umanistici, Università degli Studi Roma Tre. Roma, 10-14 giugno 2024.
Year: 2024

description: Progetto di Public History sul recupero e la valorizzazione dei canti tramandati oralmente e sul patrimonio esperienziale riguardante le due guerre mondiali
The interaction of factor VIIa with rehydrated, lyophilized platelets
Creators: name: Wolberg, Alisa S.
name: Nichols, Timothy C.
name: Bode, Arthur P.
name: Fischer, Thomas H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The experiments presented here were undertaken to determine if factor VIIa (rFVIIa, the Novo Nordisk product NovoSeven™) will directly bind to rehydrated, lyophilized (RL) platelets for the formation of a catalytic surface with an enhanced ability to generate thrombin. The interaction between rFVIIa and the RL platelet surface was examined by measuring equilibrium and non-equilibrium binding of the coagulation factor to the cells and by following the effects of the surface modification on the kinetics of thrombin generation. The association of rFVIIa with RL platelets was rapid with saturation occurring within minutes. Disassociation was slow, with over half of the coagulation factor remaining bound after two hours. Densities of over one million molecules of rFVIIa per RL platelet were obtained when high concentrations of rFVIIa were incubated with RL platelets. Thrombin generation measurements showed that RL platelet-bound rFVIIa was catalytically active. Thus we can expect that RL platelets, which have been shown to effectively bind to sites of vascular injury, will localize rFVIIa to wounds for an increase in therapeutic index. These studies indicate that rFVIIa-RL platelets are worthy of preclinical and clinical development as an infusion agent for severe bleeding.
High-pressure synthesis of superconducting Sn$_{3}$S$_{4}$ using diamond anvil cell with boron-doped diamond heater
Creators: name: Matsumoto, Ryo
name: Terashima, Kensei
name: Nakano, Satoshi
name: Nakamura, Kazuki
name: Yamamoto, Sayaka
name: Yamamoto, Takafumi D.
name: Ishikawa, Takahiro
name: Adachi, Shintaro
name: Irifune, Tetsuo
name: Imai, Motoharu
name: Takano, Yoshihiko
Publisher: name: arXiv
Year: 2022
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: High-pressure techniques open exploration of functional materials in broad research fields. An established diamond anvil cell with a boron-doped diamond heater and transport measurement terminals has performed the high-pressure synthesis of a cubic Sn$_{3}$S$_{4}$ superconductor. X-ray diffraction and Raman spectroscopy reveal that the Sn$_{3}$S$_{4}$ phase is stable in the pressure range of P>5 GPa in a decompression process. Transport measurement terminals in the diamond anvil cell detect a metallic nature and superconductivity in the synthesized Sn$_{3}$S$_{4}$ with a maximum onset transition temperature of 13.3 K at 5.6 GPa. The observed pressure-T$_{c}$ relationship is consistent with that from the first-principles calculation. The observation of superconductivity in Sn$_{3}$S$_{4}$ opens further materials exploration under high temperature and pressure conditions.
Short-term effects of announcing spirometric lung-age on smokers’ attitudes: results from a Tunisian real-life pilot study
Creators: name: Khaldi, Soumaya
name: Derbel, Khansa
name: Ghannouchi, Ines
name: Guezguez, Fatma
name: Sayhi, Amani
name: Benzarti, Wafa
name: Barkous, Balsam
name: Bouafia, Salsabil
name: Dabbebi, Fatma Zahra
name: Charfedi, Emna
name: Saad, Helmi Ben
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health
subject: Virology

description: To determine the effects of informing smokers of their spirometric lung-age (SLA) on smoking cessation (SC) rates and tobacco consumption. An interventional study was conducted in real-life through a humanitarian event led by the Red Crescent on 9 January 2022, in Hammam-Sousse (Sousse, Tunisia). The study comprised four steps: i) Medical questionnaire (general questionnaire, Fagerström test for cigarette dependence, SC motivation questionnaire); ii) Measurement of spirometric data; iii) SLA estimation and its announcement to participants; and iv) Self-reported evaluation of smoking behavior three months later through telephonic recall. Smokers were divided into groups (nondependent vs. dependent groups and insufficient/moderate motivation vs. high/very high motivation groups) and categories (ceased smoking, reduced consumption, maintained stable or increased consumption). Fifty-two smokers were included (94% were males). Three months after the event, i) 9 (17%) smokers ceased smoking, ii) 39 (75%) smokers reduced their daily smoking consumption by 12 ± 8 cigarettes/day, and iii) 4 (8%) smokers maintained stable (n = 3) or increased (n = 1) consumption. Informing smokers of their SLA led 92% of them to cease smoking or reduce their consumption. Announcing SLA could be an effective motivational tool and an easy-to-understand concept to help smokers cease their habit.
The first law for stationary axisymmetric multi-black hole systems
Creators: name: Clément, Gérard
name: Gal'tsov, Dmitry
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In the framework of Einstein-Maxwell theory, we consider collinear arrays of rotating electrically charged black holes connected by Misner-Dirac strings carrying gravimagnetic and magnetic fluxes. The first law of mechanics for these systems is derived. It involves as dynamical variables the areas, angular momenta and electric charges of the various Killing horizons -- black holes and Misner strings. When the gravimagnetic fluxes all vanish, the first law reduces to a form where the dynamical variables associated with the strings are the string tensions and magnetic fluxes. This form is not generically invariant under electric-magnetic duality.
description: 14 pages Latex, published version
Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans
Creators: name: Faurot, Keturah R.
name: Majchrzak-Hong, Sharon F.
name: Hibbeln, Joseph R.
name: Rapoport, Stanley I.
name: Berk, Michael
name: Douglas Mann, J.
name: Ringel, Amit
name: Feldstein, Ariel E.
name: Taha, Ameer Y.
name: MacIntosh, Beth A.
name: Ramsden, Christopher E.
name: Chung, Yoon-Mi
name: Cheon, Yewon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Linoleic acid (LA) is the most abundant polyunsaturated fatty acid in human diets, a major component of human tissues, and the direct precursor to the bioactive oxidized LA metabolites (OXLAMs), 9- and 13 hydroxy-octadecadienoic acid (9- and 13-HODE) and 9- and 13-oxo-octadecadienoic acid (9- and 13-oxoODE). These four OXLAMs have been mechanistically linked to pathological conditions ranging from cardiovascular disease to chronic pain. Plasma OXLAMs, which are elevated in Alzheimer’s dementia and non-alcoholic steatohepatitis, have been proposed as biomarkers useful for indicating the presence and severity of both conditions. Because mammals lack the enzymatic machinery needed for de novo LA synthesis, the abundance of LA and OXLAMs in mammalian tissues may be modifiable via diet. To examine this issue in humans, we measured circulating LA and OXLAMs before and after a 12-week LA lowering dietary intervention in chronic headache patients. Lowering dietary LA significantly reduced the abundance of plasma OXLAMs, and reduced the LA content of multiple circulating lipid fractions that may serve as precursor pools for endogenous OXLAM synthesis. These results show that lowering dietary LA can reduce the synthesis and/or accumulation of oxidized LA derivatives that have been implicated in a variety of pathological conditions. Future studies evaluating the clinical implications of diet-induced OXLAM reductions are warranted.
Probing NV and SiV charge state dynamics using high-voltage nanosecond pulse and photoluminescence spectral analysis
Creators: name: Pambukhchyan, Artur
name: Weng, Sizhe
name: Aravind, Indu
name: Cronin, Stephen B.
name: Takahashi, Susumu
Publisher: name: arXiv
Year: 2023
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Nitrogen-vacancy (NV) and silicon-vacancy (SiV) color defects in diamond are promising systems for applications in quantum technology. The NV and SiV centers have multiple charge states, and their charge states have different electronic, optical and spin properties. For the NV centers, most investigations for quantum sensing applications are targeted on the negatively charged NV (NV$^{-}$), and it is important for the NV centers to be in the NV$^{-}$ state. However, it is known that the NV centers are converted to the neutrally charged state (NV$^{0}$) under laser excitation. An energetically favorable charge state for the NV and SiV centers depends on their local environments. It is essential to understand and control the charge state dynamics for their quantum applications. In this work, we discuss the charge state dynamics of NV and SiV centers under high-voltage nanosecond pulse discharges. The NV and SiV centers coexist in the diamond crystal. The high-voltage pulses enable manipulating the charge states efficiently. These voltage-induced changes in charge states are probed by their photoluminescence spectral analysis. The analysis result from the present experiment shows that the high-voltage nanosecond pulses cause shifts of the chemical potential and can convert the charge states of NV and SiV centers with the transition rates of $\sim$ MHz. This result also indicates that the major population of the SiV centers in the sample is the doubly negatively charged state (SiV$^{2-}$), which is often overlooked because of its non-fluorescent and non-magnetic nature. This demonstration paves a path for a method of rapid manipulation of the NV and SiV charge states in the future.
description: 14 pages, 4 figures
Instrumentalkompositionen von Heinrich Bach (1615-1692)
Creators: name: Konrad, Ulrich
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Im Jahre 1662 übermittelte der Gothaer Musicus Jakob Ludwig dem in Wolfenbüttel regierenden Herzog August dem Jüngeren ein 'Partitur-Buch' mit 114 Kompositionen, die aus seiner Sicht einen Querschnitt der zeitgenössischen Instrumentalmusik in variabler Stimmenzahl und Besetzung darstellten. In dieser Sammlung sind zwei 'Sonaten à 5' des Arnstädter Organisten Heinrich Bach (1615-92), des Großonkels Johann Sebastians, überliefert. Die beiden in ihrer stilistischen Haltung auf die erste Jahrhunderthälfte weisenden Sonaten dürften Repertoirestücke von Stadt- oder Ratsmusik-Ensembles gewesen sein. Die Biographie Heinrich Bachs wird aus der auf ihn gehaltenen Leichenpredigt Johann Gottfried Olearius', aus der ausführlich zitiert wird, in den Hauptzügen rekonstruiert. (Autor, Quelle: Bibliographie des Musikschrifttums online) Vergleich auch: Peter Wollny: Zum Problem der "Instrumentalkompositionen von Heinrich Bach (1615-1692)" I. BJ 1996, S. 155-158 Ulrich Konrad: Zum Problem der "Instrumentalkompositionen von Heinrich Bach (1615-1692)" II. BJ 1996, S. 159-161
description: Bach-Jahrbuch, Bd. 81 (1995)
Dietary omega-6 fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools
Creators: name: Ramsden, Christopher E.
name: Cheon, Yewon
name: Ringel, Amit
name: Hibbeln, Joseph R.
name: MacIntosh, Beth
name: Faurot, Keturah F.
name: Taha, Ameer Y.
name: Mann, J. Douglas
name: Majchrzak-Hong, Sharon F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Dietary linoleic acid (LA, 18:2n-6) lowering in rats reduces n-6 polyunsaturated fatty acid (PUFA) plasma concentrations and increases n-3 PUFA (eicosapentaenoic (EPA) and docosahexaenoic acid (DHA)) concentrations.
Die geistlichen Vokalwerke von Johann Christoph Friedrich Bach
Creators: name: Leisinger, Ulrich
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Einer ästhetischen Bewertung von Johann Christoph Friedrich Bachs Vokalwerken muß eine nüchterne Bestandsaufnahme mit dem Ziel, Echtheit und Chronologie seines kirchenmusikalischen Schaffens zu bestimmen, vorangehen. Der Autor skizziert die Grundzüge der Entstehungs- und Überlieferungsgeschichte der Kantaten und Oratorien Bachs. Dabei widmet er sich insbesondere den Umständen seines Schaffen in Bückeburg und seiner Zusammenarbeit mit Johann Gottfried Herder. Die Choralsätze Johann Sebastian Bachs, die Johann Christoph Friedrich in eigene Vokalwerke (z. B. das Oratorium 'Der Tod Jesu') übernommen hat, sind in einer Tabelle aufgelistet. (Dorothea Wagner, Quelle: Bibliographie des Musikschrifttums online)
description: Bach-Jahrbuch, Bd. 81 (1995)
On the L$_\infty$ structure of Poisson gauge theory
Creators: name: Abla, O.
name: Kupriyanov, V. G.
name: Kurkov, M.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The Poisson gauge theory is a semi-classical limit of full non-commutative gauge theory. In this work we construct an L$_\infty^{full}$ algebra which governs both the action of gauge symmetries and the dynamics of the Poisson gauge theory. We derive the minimal set of non-vanishing $\ell$-brackets and prove that they satisfy the corresponding homotopy relations. On the one hand, it provides new explicit non-trivial examples of L$_\infty$ algebras. On the other hand, it can be used as a starting point for bootstrapping the full non-commutative gauge theory. The first few brackets of such a theory are constructed explicitly in the text. In addition we show that the derivation properties of $\ell$-brackets on L$_\infty^{full}$ with respect to the truncated product on the exterior algebra are satisfied only for the canonical non-commutativity. In general, L$_\infty^{full}$ does not have a structure of P$_\infty$ algebra.
description: 30 pages, matches with a published version
When policy and practice collide: a structuration approach examining the failure to unify an organization
Creators: name: Slade, Bret
name: Pech, Richard
name: Muir, Stephen
Publisher: name: La Trobe
Year: 2023

description: Graduate School of Management

Australian and New Zealand Academy of Management. International conference (20th : 2006 : Yeppoon, Australia)
Synchrotron pair halo and echo emission from blazars in the cosmic web: application to extreme TeV blazars
Creators: name: Oikonomou, Foteini
name: Murase, Kohta
name: Kotera, Kumiko
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: High frequency peaked high redshift blazars, are extreme in the sense that their spectrum is particularly hard and peaks at TeV energies. Standard leptonic scenarios require peculiar source parameters and/or a special setup in order to account for these observations. Electromagnetic cascades seeded by ultra-high energy cosmic rays (UHECR) in the intergalactic medium have also been invoked, assuming a very low intergalactic magnetic field (IGMF). Here we study the synchrotron emission of UHECR secondaries produced in blazars located in magnetised environments, and show that it can provide an alternative explanation to these challenged channels, for sources embedded in structured regions with magnetic field strengths of the order of $10^{-7}$ G. To demonstrate this, we focus on three extreme blazars: 1ES 0229+200, RGB J0710+591, and 1ES 1218+304. We model the expected gamma-ray signal from these sources through a combination of numerical Monte Carlo simulations and solving the kinetic equations of the particles in our simulations, and explore the UHECR source and intergalactic medium parameter space to test the robustness of the emission. We show that the generated synchrotron pair halo/echo flux at the peak energy is not sensitive to variations in the overall IGMF strength. This signal is unavoidable in contrast to the inverse Compton pair halo/echo intensity, which is appealing in view of the large uncertainties on the IGMF in voids of large scale structure. It is also shown that the variability of blazar gamma-ray emission can be accommodated by the synchrotron emission of secondary products of UHE neutral beams if these are emitted by UHECR accelerators inside magnetised regions.
description: 11 pages, 9 figures, to appear in A&A
Pten Dose Dictates Cancer Progression in the Prostate
Creators: name: Roy-Burman, Pradip
name: Xiao, Andrew
name: Trotman, Lloyd C
name: Cordon-Cardo, Carlos
name: Khoo, Alan S
name: Dyke, Terry Van
name: Dotan, Zohar A
name: Pandolfi, Pier Paolo
name: Niki, Masaru
name: Greenberg, Norman M
name: Koutcher, Jason A
name: Di Cristofano, Antonio
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2003

description: Complete inactivation of the PTEN tumor suppressor gene is extremely common in advanced cancer, including prostate cancer (CaP). However, one PTEN allele is already lost in the vast majority of CaPs at presentation. To determine the consequence of PTEN dose variations on cancer progression, we have generated by homologous recombination a hypomorphic Pten mouse mutant series with decreasing Pten activity: Ptenhy/+ > Pten+/− > Ptenhy/− (mutants in which we have rescued the embryonic lethality due to complete Pten inactivation) > Pten prostate conditional knockout (Ptenpc) mutants. In addition, we have generated and comparatively analyzed two distinct Ptenpc mutants in which Pten is inactivated focally or throughout the entire prostatic epithelium. We find that the extent of Pten inactivation dictate in an exquisite dose-dependent fashion CaP progression, its incidence, latency, and biology. The dose of Pten affects key downstream targets such as Akt, p27Kip1, mTOR, and FOXO3. Our results provide conclusive genetic support for the notion that PTEN is haploinsufficient in tumor suppression and that its dose is a key determinant in cancer progression.
Efficacy and safety of bronchoscopic lung volume reduction for chronic obstructive pulmonary disease: a systematic review and network meta-analysis
Creators: name: Zhang, Ranran
name: Zheng, Ziwen
name: Bian, Yiding
name: Deng, Mingming
name: Herth, Felix F. J.
name: Hou, Gang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Various bronchoscopic lung volume reduction (BLVR) methods have been developed to treat chronic obstructive pulmonary disease (COPD). The efficacy and safety of these interventions remain unclear. This study assessed the efficacy and safety of various BLVR interventions in COPD patients. PubMed and Embase were searched from inception to 21 October 2023. The primary outcomes assessed included the 6-min walking distance (6MWD), St. George Respiratory Questionnaire (SGRQ) score, lung function, and adverse events (AE). A frequentist approach with a random-effects model was used for a network meta-analysis. Twelve randomized controlled trials (RCTs) with 1646 patients were included in this meta-analysis. Patients treated with an endobronchial valve (EBV) achieved a minimum clinically important difference (MCID) in 6MWD and SGRQ at 6 months. Patients treated with coils achieved MCID in the SGRQ score at 12 months. Patients with aspiration valve system and bronchoscopic thermal vapor ablation (BTVA) achieved MCID in the SGRQ score at 6 months. In COPD patients, EBV should be considered first, while being wary of pneumothorax. Coil and BTVA are potential therapeutic alternatives. Although BTVA demonstrates a safer procedural profile than coils, additional studies are imperative to clarify its efficacy.
Dictyostelium Myosin Bipolar Thick Filament Formation: Importance of Charge and Specific Domains of the Myosin Rod
Creators: name: Hostetter, Daniel
name: Altman, David
name: Dean, Sara
name: Spudich, James A
name: Rice, Sarah
name: Sutton, Shirley
name: Tripathy, Ashutosh
name: McMahon, Peggy M
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Myosin-II thick filament formation in Dictyostelium is an excellent system for investigating the phenomenon of self-assembly, as the myosin molecule itself contains all the information required to form a structure of defined size. Phosphorylation of only three threonine residues can dramatically change the assembly state of myosin-II. We show here that the C-terminal 68 kDa of the myosin-II tail (termed AD-Cterm) assembles in a regulated manner similar to full-length myosin-II and forms bipolar thick filament (BTF) structures when a green fluorescent protein (GFP) “head” is added to the N terminus. The localization of this GFP-AD-Cterm to the cleavage furrow of dividing Dictyostelium cells depends on assembly state, similar to full-length myosin-II. This tail fragment therefore represents a good model system for the regulated formation and localization of BTFs. By reducing regulated BTF assembly to a more manageable model system, we were able to explore determinants of myosin-II self-assembly. Our data support a model in which a globular head limits the size of a BTF, and the large-scale charge character of the AD-Cterm region is important for BTF formation. Truncation analysis of AD-Cterm tail fragments shows that assembly is delicately balanced, resulting in assembled myosin-II molecules that are poised to disassemble due to the phosphorylation of only three threonines.
Efficacy and safety of bronchoscopic lung volume reduction for chronic obstructive pulmonary disease: a systematic review and network meta-analysis
Creators: name: Zhang, Ranran
name: Zheng, Ziwen
name: Bian, Yiding
name: Deng, Mingming
name: Herth, Felix Jf
name: Hou, Gang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Various bronchoscopic lung volume reduction (BLVR) methods have been developed to treat chronic obstructive pulmonary disease (COPD). The efficacy and safety of these interventions remain unclear. This study assessed the efficacy and safety of various BLVR interventions in COPD patients. PubMed and Embase were searched from inception to 21 October 2023. The primary outcomes assessed included the 6-min walking distance (6MWD), St. George Respiratory Questionnaire (SGRQ) score, lung function, and adverse events (AE). A frequentist approach with a random-effects model was used for a network meta-analysis. Twelve randomized controlled trials (RCTs) with 1646 patients were included in this meta-analysis. Patients treated with an endobronchial valve (EBV) achieved a minimum clinically important difference (MCID) in 6MWD and SGRQ at 6 months. Patients treated with coils achieved MCID in the SGRQ score at 12 months. Patients with aspiration valve system and bronchoscopic thermal vapor ablation (BTVA) achieved MCID in the SGRQ score at 6 months. In COPD patients, EBV should be considered first, while being wary of pneumothorax. Coil and BTVA are potential therapeutic alternatives. Although BTVA demonstrates a safer procedural profile than coils, additional studies are imperative to clarify its efficacy.
Analysis of Solar-like X-Class Flare on Wolf 359 Observed Simultaneously with TESS and XMM-Newton
Creators: name: Pietras, Małgorzata
name: Falewicz, Robert
name: Siarkowski, Marek
name: Kepa, Anna
name: Bicz, Kamil
name: Preś, Paweł
Publisher: name: arXiv
Year: 2023
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present an analysis of a flare on the Wolf 359 star based on simultaneous observations of TESS and XMM-Newton. A stellar flare with energy comparable to an X-class solar flare is analyzed on this star for the first time. The main goal of the study was to determine whether the same physical processes drive and occur in stellar flares as in the solar flares. We tried to estimate the flare class by various direct and indirect methods. Light curves and spectra in different energy ranges were used to determine the parameters and profiles of the flare. From the XMM-Newton EPIC-pn X-ray data, we estimated the temperature and emission measure during the flare. The thermodynamical timescale and the loop semi-length were also determined with two different methods. The RGS spectra enabled us to calculate the differential emission measure (DEM) distributions. The obtained DEM distributions have three components at temperature values of 3 MK, 7 MK, and 16-17 MK. The analysis of the line ratio in helium-like triplets allowed us to determine the plasma electron density. Our results for the flare loop on Wolf 359 were compared to typical parameters for solar flares observed with GOES and RHESSI. This supports our conclusion that the processes taking place in stellar flares are like those in solar flares. The determined geometrical parameters of the phenomenon do not differ from the values of analogs occurring on the Sun.
description: 13 pages, 8 figures, accepted to ApJ
Online Caching with Optimistic Learning
Creators: name: Mhaisen, Naram
name: Iosifidis, George
name: Leith, Douglas
Publisher: name: arXiv
Year: 2022
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The design of effective online caching policies is an increasingly important problem for content distribution networks, online social networks and edge computing services, among other areas. This paper proposes a new algorithmic toolbox for tackling this problem through the lens of optimistic online learning. We build upon the Follow-the-Regularized-Leader (FTRL) framework which is developed further here to include predictions for the file requests, and we design online caching algorithms for bipartite networks with fixed-size caches or elastic leased caches subject to time-average budget constraints. The predictions are provided by a content recommendation system that influences the users viewing activity, and hence can naturally reduce the caching network's uncertainty about future requests. We prove that the proposed optimistic learning caching policies can achieve sub-zero performance loss (regret) for perfect predictions, and maintain the best achievable regret bound $O(\sqrt T)$ even for arbitrary-bad predictions. The performance of the proposed algorithms is evaluated with detailed trace-driven numerical tests.
description: To appear in IFIP Networking 2022
TwistSLAM: Constrained SLAM in Dynamic Environment
Creators: name: Gonzalez, Mathieu
name: Marchand, Eric
name: Kacete, Amine
name: Royan, Jérôme
Publisher: name: arXiv
Year: 2022
Subjects: subject: Robotics (cs.RO)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Classical visual simultaneous localization and mapping (SLAM) algorithms usually assume the environment to be rigid. This assumption limits the applicability of those algorithms as they are unable to accurately estimate the camera poses and world structure in real life scenes containing moving objects (e.g. cars, bikes, pedestrians, etc.). To tackle this issue, we propose TwistSLAM: a semantic, dynamic and stereo SLAM system that can track dynamic objects in the environment. Our algorithm creates clusters of points according to their semantic class. Thanks to the definition of inter-cluster constraints modeled by mechanical joints (function of the semantic class), a novel constrained bundle adjustment is then able to jointly estimate both poses and velocities of moving objects along with the classical world structure and camera trajectory. We evaluate our approach on several sequences from the public KITTI dataset and demonstrate quantitatively that it improves camera and object tracking compared to state-of-the-art approaches.
description: This work has been accepted at IEEE Robotics and Automation Letters
Die Versteigerung von C. P. E. Bachs musikalischem Nachlaß im Jahre 1805
Creators: name: Kulukundis, Elias N.
Publisher: name: Bach-Jahrbuch
Year: 2018

description: Der Artikel befasst sich mit den Umständen der Auktion, bei der der musikalische Nachlass Carl Philipp Emanuel Bachs in Hamburg versteigert wurde. Es werden die Vorgehensweise bei der Versteigerung und die Käufer dargestellt. Weiterhin enthält der Artikel Faksimiles der den Bach-Nachlass betreffenden Seiten des Auktionskataloges (S. 154-158) und eine kommentierte Wiedergabe desselben (soweit identifizierbar genaue Bezeichnung des jeweiligen Werks nach Wotquenne und Helm und verbleib der im Katalog beschriebenen Quelle, S. 159-176) Erwähnter Artikel: Ulrich Leisinger: Die ,Bachsche Auction' von 1789. BJ 1991, S. 97-126 Vergleiche auch: Heinrich Miesner: Philipp Emanuel Bachs musikalischer Nachlaß. Vollständiger, dem Original entsprechender Neudruck des Nachlaßverzeichnisses von 1790. BJ 1938, S. 103-136 Heinrich Miesner: Philipp Emanuel Bachs musikalischer Nachlaß. Vollständiger, dem Original entsprechender Neudruck des Nachlaßverzeichnisses von 1790 (Fortsetzung). BJ 1939, S. 81-112 Heinrich Miesner: Philipp Emanuel Bachs musikalischer Nachlaß. Vollständiger, dem Original entsprechender Neudruck des Nachlaßverzeichnisses von 1790 (Fortsetzung und Schluß). BJ 1940-48, S. 161-168
description: Bach-Jahrbuch, Bd. 81 (1995)
Discovery of Recombining Plasma in the Supernova Remnant 3C 391
Creators: name: Sato, Tamotsu
name: Koyama, Katsuji
name: Takahashi, Tadayuki
name: Odaka, Hirokazu
name: Nakashima, Shinya
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Recent X-ray study of middle-aged supernova remnants (SNRs) reveals strong radiative recombination continua (RRCs) associated with overionized plasmas, of which the origin still remains uncertain. We report our discovery of an RRC in the middle-aged SNR 3C 391. If the X-ray spectrum is fitted with a two-temperature plasma model in collisional ionization equilibrium (CIE), residuals of Si XIV Ly alpha line at 2.006 keV, S XVI Ly alpha line at 2.623 keV and the edge of RRC of Si XIII at 2.666 keV are found. The X-ray spectrum is better described by a composite model consisting of a CIE plasma and a recombining plasma (RP). The abundance pattern suggests that the RP is associated to the ejecta from a core-collapse supernova with a progenitor star of 15 solar mass. There is no significant difference of the recombining plasma parameters between the southeast region and the northwest region surrounded by dense molecular clouds. We also find a hint of Fe I K alpha line at 6.4 keV (~2.4 sigma detection) from the southeast region of the SNR.
description: 15 pages, 8 figures, accepted for publication in PASJ
pRb Inactivation in Mammary Cells Reveals Common Mechanisms for Tumor Initiation and Progression in Divergent Epithelia
Creators: name: Lu, Lucy
name: Cardiff, Robert D
name: Wu, Hua
name: Dyke, Terry Van
name: Albertson, Donna
name: Simin, Karl
name: Pinkel, Dan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2004

description: Retinoblastoma 1 (pRb) and the related pocket proteins, retinoblastoma-like 1 (p107) and retinoblastoma-like 2 (p130) (pRbf, collectively), play a pivotal role in regulating eukaryotic cell cycle progression, apoptosis, and terminal differentiation. While aberrations in the pRb-signaling pathway are common in human cancers, the consequence of pRbf loss in the mammary gland has not been directly assayed in vivo. We reported previously that inactivating these critical cell cycle regulators in divergent cell types, either brain epithelium or astrocytes, abrogates the cell cycle restriction point, leading to increased cell proliferation and apoptosis, and predisposing to cancer. Here we report that mouse mammary epithelium is similar in its requirements for pRbf function; Rbf inactivation by T121, a fragment of SV40 T antigen that binds to and inactivates pRbf proteins, increases proliferation and apoptosis. Mammary adenocarcinomas form within 16 mo. Most apoptosis is regulated by p53, which has no impact on proliferation, and heterozygosity for a p53 null allele significantly shortens tumor latency. Most tumors in p53 heterozygous mice undergo loss of the wild-type p53 allele. We show that the mechanism of p53 loss of heterozygosity is not simply the consequence of Chromosome 11 aneuploidy and further that chromosomal instability subsequent to p53 loss is minimal. The mechanisms for pRb and p53 tumor suppression in the epithelia of two distinct tissues, mammary gland and brain, are indistinguishable. Further, this study has produced a highly penetrant breast cancer model based on aberrations commonly observed in the human disease.