cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Neural representation of geoinformation in the human brain: affected by abstraction levels and spatial scales
Creators: name: Yang, Tianyu
name: Zhao, Bo
name: Gao, Song
name: Dong, Weihua
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Space Science
Medicine
Neuroscience
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: The rapid development of cartographical methods has led to cognitive differences in the user experience, presenting a new challenge to microscale research on geoinformation. Prior studies have been constrained by methodologies, and how the human brain represents geoinformation with different levels of abstraction across geographic scales remains unclear. In this study, we conducted a cognitive experiment using functional magnetic resonance imaging with thirteen participants to explore the neural representations of geoinformation abstraction levels and spatial scales. Univariate analysis was utilized to examine the task-state brain imaging representations, and representational similarity analysis was employed to quantify the correlation between two variables and brain signals. We found that the increase in the geoinformation abstraction level decreases the activity of working memory processing, and 3D image induces users to organize geoinformation using egocentric spatial references. Extremely high or low levels of abstraction can hinder effective visual attention allocation. To the best of our knowledge, this is the first report on the neural representation of geoinformation’s abstraction levels and spatial scales, offering new neuroimaging evidence for the theoretical framework of cartography and providing an empirical spatial cognition foundation for future cartographic design.
A big data approach to modelling urban population density functions: from monocentricity to polycentricity
Creators: name: Luo, Cehong
name: Hu, Yujie
name: Wang, Fahui
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cardiology

description: Urban studies have a long tradition of examining the regularity of urban structure by modelling urban population density functions and probing the theoretical or behavioural foundation behind it. Previous studies commonly used census data in areal units such as census tracts or census block groups, which varied a great deal in area size and shape and led to the zonal and scale effects, commonly referred to as the modifiable areal unit problem (MAUP). This study uses big data of individual vehicle trips in Tampa, Florida, to define the precise population and employment distribution locations, and then aggregates them with uniform areal units such as squares, triangles, and hexagons to examine and mitigate the scale and zonal effects. Both monocentric and polycentric models are employed in the analysis of urban population density functions. The results suggest that the exponential density function remains the best fitting monocentric function in most areal units including census units and designed uniform units. The polycentric model reveals two centres (downtown and University of South Florida) exerting influences on the areawide population density pattern. The zonal effect is not significant in the designed uniform units, but the scale effect remains evident in all areal units.
E03661: Fragments from one or more ecclesiastical document(s) in Greek on papyrus, probably mentioning a church dedicated to *Mary (Mother of Christ, S00033), likely to be the cathedral of Petra, and, probably, a monastic establishment named after a certain 'Theodoros'. Found in Petra (Roman province of Palaestina III). Dated c. 561.
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: Fragment 1

Entry 48 in the fourth volume of the Petra papyri contains fragments extracted from one of two poorly preserved chunks of papyrus. The two chunks consist of more than 500 fragments, but within the first chunk only 27 were identified as bearing intelligible text, preserving a total of 55 lines. Some of the fragments were conjoining, but it is not clear whether they all belong to the same document, as the chunk could have been a bundle of several rolls. Matias Buchholz and Traianos Gagos offered an edition following the order in which the fragments were extracted from the chunk. Therefore, their text does not mirror the order of the contents of the document(s). The second fragment (Fragment Ba 6V) says:

τῆ]ς ἁγίας Μαρία[ς

'] of the Holy Mary ['

The editors associate it with a fragment from the other chunk (P.Petra IV 49) which mentions 'the most holy church of the metropolis of the Petraeans' (τῆς ἁγι]ωτ(άτης) ἐκκλ̣ησ(ίας) τῆς Πετρα[ίων] ̣μ̣η[τροπόλεως) and argue that this is the church where the papyri were found, and that it was dedicated to Mary.

Fragments 2 and 3

In addition, fragment Ba21V [+Bb 17R] says τ]ῷ ὄρει τοῦ ὁσιωτ(άτου) Θεοδώρου/'on the mount of the most reverend Thedoros' and fragment Bba 2R καὶ διακονίαν ὄρῃ ἱερῷ | [τοῦ ὁσιωτ(άτου) Θεοδώρου]/'and service on the holy mount [of the most reverend Theodoros]' (the completion of this second line being, of course, hypothetical). The editors probably rightly argue that this is 'an institution, probably a religious one'. This could be a monastery named after its founder. The designation ὄρος/'mountain' was often associated with monasteries or desolate places (in the context of Egyptian papyri it often means 'desert'). The epithet ὁσιώτατος suggests that the eponym was a monk rather than *Theodore, the soldier and martyr of Euchaita in Pontus (S00136).

The document(s) touch(es) upon the following issues: 'daily wages of ministers', 'lighting the candles', 'service' or 'ministration', 'rent', 'lease', probably some cultivated property. 'Public dues', taxes, and gold coins/carats of gold may also be mentioned. Thus the entire document(s) appear(s) to have dealt with financial issues of the church. Theodoros, son of Obodianos, the key figure in the entire archive, is mentioned here probably as acting on behalf of the church in the capacity of his office. Bishop Ioannes, one Leontios, possibly Stephanos, son of Leontios, and Kyra are also mentioned.

Dating: By chance a fragment (Ba 9V + Bb 15R) with a date, the month of Loos, the year 456 of the era of the province of Arabia, convertible to 20 July - 18 August AD 561, was preserved in the lot.

Text: P.Petra IV 48.
Hematuria and fever in a patient with polycystic kidney disease, a case report
Creators: name: Min, Wouter
Publisher: name: EURORAD
Year: 2017
Subjects: subject: Kidney
subject: Urinary Tract / Bladder
subject: CT
subject: Diagnostic procedure
subject: Infection

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: female, 68 years
description: Clinical History: A 68-year-old female patient with polycystic kidney disease presented with high fever, macroscopic hematuria and pain in the right flank. Laboratory studies revealed renal impairment (2.87 mg/dl serum creatinine) and markedly increased C-reactive protein ... Final Diagnosis: Emphysematous cystitis and pyelonephritis
E03662: Fragmentary tax receipt written in Greek on papyrus, mentioning tax due to shrines of *Theodore (probably the soldier and martyr of Euchaita, S00480), and perhaps an *Archangel. Found in Petra, drafted in Petra or Kastron Zadakathon/Sadaqa (Roman province of Palaestina III). Dated 565/575.
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: lines 26-39:

[- ca.11 -]ς δεκάτης ἰνδι(κτίωνος) καὶ αὐτῆς. καὶ τοῦτο δὲ δῆλον ποιῶ ν[ -0-6- ]
[....] .... ̣π[αν]τοίου δόλω τῷ ἰδίω{ν} μου κυνδύνῳ κ[α]ὶ τῆς ἐμ[ε͂ς] [ὑποστά]-
[- - -]σεως καὶ ε̣ὐτ[...].̣οα̣ρ.......[- ca.30 -]
[..]ς ἀπὸ ἑνδε[κάτης ἰνδι(κτίωνος) - ca.32 -]
[- ca.10 - ἡ] [ἐ]μὲ σύνβιως τοῦ προγεγραμμένου π ..[.].. ̣[ -3-6- ]
[- ca.11 -] τῆς αὐτῆς συντηλείας τοῖς εὐαγέσιν οἴκοις τῶν [ἁγίων]
[κα]̣ὶ ἐνδόξ[ων ...].τοῦ ἀρχο.[.....]υ καὶ Θεωδό̣ρ[ο]υ τοῦ μάρτ[υρος ἐπὶ (?)]
[ -ca.?- ] ̣Ζ[α]δακάθο̣υ [τοῦ εἰρη]̣μέ̣νου κάστρ[ου - ca.28 -]
[τ]ῷ ̣μ̣α̣κ̣α̣ρ̣ι̣ω̣τ(άτῳ) .[...].[.] ̣ἐμῷ π̣ε̣νθ̣ηρῷ ἀπ[ὸ - ca.25 -]
[.... ἐκχωρη]̣θείσης ὑπ' αὐτοῦ τοῖς αὐτοῖς ἁγίοις οἴκοις καὶ ...[ -0-6- ]
[..]...[...] ̣τοὺς κληρονόμους καὶ διαδόχους καὶ τὼ ἀζέμιω[ν] [καὶ]
[- - -] ἀβλαβὲς [καὶ ἀ]̣νενόχλητον καὶ [- ca.12 - περ]̣ιποιέσ̣ο[ -0-7- ]
[- - -]... κ̣α̣ὶ κλ[ηρον]όμοι ... διάδοχοι ἐκ [- ca.30 -]

'And I affirm this [- - - without] any treachery, with my own personal liability and that of my property and [- - -] from the eleventh [indiction - - -] my spouse, of the above-mentioned [- - -] of the same tax to the sacred houses (euageis oikoi) of the [holy and] glorious [- - -] the Arch[angel?] and Theodore the Martyr [in] Zadakathon, the said Kastron, [- - -] to my most blessed father-in-law [- - -], from [- - - ceded] by him to the same holy houses (hagioi oikoi) and [- - -] the heirs and successors, and free from liability [and] unharmed [and] undisturbed and [- - -] keep [- - -] and the heirs [and] successors [- - -].'

Text: P.Petra IV 37. Translation: A. Arjava, T. Gagos, lightly adapted.
sj-pdf-1-fst-10.1177_1082013220980586 - Supplemental material for Inulin gelled emulsion as a fat replacer and fiber carrier in healthier Bologna sausage
Creators: name: Paglarini, Camila De Souza
name: Vitor Andre Silva Vidal
name: Maristela Midori Ozaki
name: Ribeiro, Ana Paula Badan
name: Oigres Daniel Bernardinelli
name: Câmara, Ana Karoline Ferreira Ignácio
name: Herrero, Ana M
name: Ruiz-Capillas, Claudia
name: Edvaldo Sabadini
name: Pollonio, Marise Aparecida Rodrigues
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-fst-10.1177_1082013220980586 for Inulin gelled emulsion as a fat replacer and fiber carrier in healthier Bologna sausage by Camila de Souza Paglarini, Vitor Andre Silva Vidal, Maristela Midori Ozaki, Ana Paula Badan Ribeiro, Oigres Daniel Bernardinelli, Ana Karoline Ferreira Ignácio Câmara, Ana M Herrero, Claudia Ruiz-Capillas, Edvaldo Sabadini and Marise Aparecida Rodrigues Pollonio in Food Science and Technology International
HUSTLE HARDER: ENHANCING BLACK WOMEN EDUCATORS' ABILITY TO MAKE DATA-BASED DECISIONS IN READING
Creators: name: Pullings, Khristina
Publisher: name: ProQuest
Year: 2025
Subjects: classificationCode: 39
subject: Education
classificationCode: 390307
subject: Teacher education and professional development of educators
classificationCode: 390104
subject: English and literacy curriculum and pedagogy (excl. LOTE, ESL and TESOL)

description: Data-based instruction is a powerful educational tool, helping teachers tailor their approach to meet student needs. Implementing data-based instructional decisions can help alleviate the “hustle culture” affecting Black women educators (BWE). The data-based approach emphasizes that the purpose of data-based instruction is to support student learning, rather than intensify workload or pressure. “Hustle culture” synthesizes societal pressures to constantly work hard at the expense of rest, leisure, or well-being. For Black women educators, this “hustle
culture” is particularly challenging due to the intersection of systemic inequalities, gender and racial biases, and high expectations. BWE often encounter pressures to work harder, maintain the status quo, and take on additional responsibilities to prove their capabilities. Moreover, stereotypes and biases can generate additional stress by expecting BWE to embody specific traits or fulfill particular roles in the educational setting, such as mentoring Black students and modeling resilience and excellence amid systemic barriers. To address these challenges, educators must ensure that data analysis considers diverse backgrounds and student experiences, recognizing that various factors may influence student performance. Providing adequate training and support for BWE in data analysis and interpretation can empower them to use data effectively without exacerbating their workload.
sj-pdf-4-fst-10.1177_1082013220980586 - Supplemental material for Inulin gelled emulsion as a fat replacer and fiber carrier in healthier Bologna sausage
Creators: name: Paglarini, Camila De Souza
name: Vitor Andre Silva Vidal
name: Maristela Midori Ozaki
name: Ribeiro, Ana Paula Badan
name: Oigres Daniel Bernardinelli
name: Câmara, Ana Karoline Ferreira Ignácio
name: Herrero, Ana M
name: Ruiz-Capillas, Claudia
name: Edvaldo Sabadini
name: Pollonio, Marise Aparecida Rodrigues
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-4-fst-10.1177_1082013220980586 for Inulin gelled emulsion as a fat replacer and fiber carrier in healthier Bologna sausage by Camila de Souza Paglarini, Vitor Andre Silva Vidal, Maristela Midori Ozaki, Ana Paula Badan Ribeiro, Oigres Daniel Bernardinelli, Ana Karoline Ferreira Ignácio Câmara, Ana M Herrero, Claudia Ruiz-Capillas, Edvaldo Sabadini and Marise Aparecida Rodrigues Pollonio in Food Science and Technology International
Experimental Demonstration of Lunar Water Extraction and Purification
Creators: name: Zabel, Paul
name: Kiewiet, Luca
Publisher: name: Zenodo
Year: 2024

description: Sustainable space exploration requires the development of In-Situ Resource Utilization (ISRU) technologies, which encompass all processes that utilize local resources to generate useful products for robotic and human exploration. Among the available resources, water is the most versatile and most needed in space exploration. Water can be directly used as consumable for astronauts or electrolyzed to hydrogen and oxygen, a very effective rocket propellant combination. However, in-situ water extraction is challenging and the required technologies are not yet fully developed. The LUWEX project focuses on the development and validation of a complete in-situ water process chain including water extraction, purification and quality monitoring. An integrated test setup was built to validate the operational capabilities of these technologies and also of the whole process chain. This setup delivers a relatively realistic environment analogue to the lunar surface and uses a lunar dust-ice simulant to provide proper validation conditions. The goal of the experiments is to demonstrate the extraction and purification of one liter of water. The project team is going to present the first experiment results of the LUWEX project which will enable future water extraction an purification for consumables and propellant production on the Moon.
Synovial chondromatosis in a patient with atypical rheumatoid arthritis confirmed by clinical, radiographic, and pathological evidence: a case report
Creators: name: Li, CH
name: Gao, JL
name: Ren, C
name: Yang, SM
name: Hou, YY
name: He, ZH
name: Zhao, JX
name: Yang, YP
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Synovial chondromatosis in a patient with atypical rheumatoid arthritis confirmed by clinical, radiographic, and pathological evidence: a case report
Libertà di coscienza e di religione. Ragioni e proposte per un intervento legislativo
Creators: name: Zaccaria, Roberto
Publisher: name: Università degli Studi di Milano
Year: 2017
Subjects: Libertà di coscienza e di religione

description: Brevi note introduttive al Seminario di studi organizzato dalla Fondazione Astrid [Roma, 6 aprile 2017, Sala Zuccari (9,30 – 13,15) in Via della Dogana Vecchia, 29, e Sala di rappresentanza del banco BPM (14,30 – 18,00), Palazzo Altieri, in Piazza del Gesù, 49].
description: Stato, Chiese e pluralismo confessionale, 2017: 3 aprile
E03664: Request for the transfer of taxation following the acquisition of a plot of land by the church, and probably monastery, of *Theodore (probably the soldier and martyr of Amaseia and Euchaita, S00480) in Ammatha, near Petra. Written in Greek on papyrus. Found in Petra (Roman province of Palaestina III). Dated 559.
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: lines 3-5:

[Θ]εόδωρ[ο]ς Ὀβοδιανοῦ διάκο̣νος τῆς ̣κ[αὶ ὑ]πὸ τήνδε τὴν [πό]̣λιν [ἁ]γιωτάτη[ς] κ[α]θολικῆς ἐκλησίας ἐπιστέλλω τὰ ὑποτεταγμένα· ἐπείπερ τῇ σήμερον

ἡμέρ̣ᾳ πέπρα[κα] τῷ θεοφι̣λεστάτ[ῳ] Φιλο̣υ̣μέ[ν]ῳ Γερ[οντ]ίου [πρεσβυτέρῳ] ̣καὶ συν[.]ο... ̣τ̣οῦ ἐν Α[μμ]εθᾳ διακειμ̣έ[ν]ου εὐαγοῦς ̣οἴκο̣υ τ̣ο[ῦ ἁ]γίου καὶ ἐνδόξου [μ]άρτυρος Θε[ο]δώρου ὀνό̣μ[ατ]̣ι τοῦ αὐτοῦ ἁ[γί]ου τόπ̣ο[υ] τ[ὴ]ν διαφέρουσάν μ[οι] ἐπί[ρρυ]τον

μ[ίαν γ]εωργίαν [ἐν .]̣αινᾳ τῷ ἐποικείῳ τῷ περ̣ὶ [τὴ]ν Αὐγουστόπολι[ν διακει]μένῳ λεγομέ[ν(ην)] Μαλ ε[λ]-Αμοα[? - - - ἤ]̣τοι Μαλ [αλ]-Εθερρο[..]εϊ̣βα

'I, Theodoros, son of Obodianos, deacon of the most holy catholic church under (the control of?) this city, notify (you) of the following.

Since on this very day I sold to the most God-pleasing Philoumenos, son of Gerontios, [presbyter] and... of the sacred shrine of the holy and glorious martyr Theodore, located in Ammetha, on behalf of the said holy place, [one] well-watered field that belongs to me [in] the hamlet [- - -]aina, [situated] near Augustopolis, called Mal-el-Amoa[? - - -] or Mal-[al]-Etherro[..]eiba...'

Text: P.Petra III 25. Translation: T. Gagos, L. Koenen.
sj-pdf-1-msc-10.1177_0969141320986830 - Supplemental material for Classifying interval cancers as false negatives or newly occurring in fecal immunochemical testing
Creators: name: Hsu, Wen-Feng
name: Hsu, Chen-Yang
name: Yen, Amy Ming-Fang
name: Chen, Sam Li-Sheng
name: Chiu, Sherry Yueh-Hsia
name: Fann, Jean Ching-Yuan
name: Yi-Chia Lee
name: Han-Mo Chiu
name: Hsiu-Hsi Chen
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111402 Obstetrics and Gynaecology
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-msc-10.1177_0969141320986830 for Classifying interval cancers as false negatives or newly occurring in fecal immunochemical testing by Wen-Feng Hsu, Chen-Yang Hsu, Amy Ming-Fang Yen, Sam Li-Sheng Chen, Sherry Yueh-Hsia Chiu, Jean Ching-Yuan Fann, Yi-Chia Lee, Han-Mo Chiu and Hsiu-Hsi Chen in Journal of Medical Screening
Additional file 9 of Identification of RimR2 as a positive pathway-specific regulator of rimocidin biosynthesis in Streptomyces rimosus M527
Creators: name: Li, Huijie
name: Hu, Yefeng
name: Zhang, Yongyong
name: Ma, Zheng
name: Bechthold, Andreas
name: Yu, Xiaoping
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9: Figure S8. HPLC analysis of rimocidin isolated from fermentation extracts of the recombinant strains S. rimosus M527-KR, S. rimosus M527-NR, S. rimosus M527-ER, S. rimosus M527-21R, S. rimosus M527-57R and WT strain S. rimosus M527.
E03665: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 1 March *Silvester (bishop of Rome, ob. 336, S00397), and possibly *Paulos and Iouliana (martyrs in Ptolemais, S01535), and *Eudokia (martyr of Heliopolis-Baalbek, S00873).
Creators: name: Naleksidze
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: ა. ანასტასია წ(მიდ)ას, ჴს(ე)ნ(ე)ბ(ა)ჲ სილიბისტროს მამ(ა)დ\მთ(ა)ვრისა დიდისა ჰრომის(ა)ჲ, და პ(ა)ვლესი და გერმანაჲსი წ(მი\და)თაჲ, და ევდოკია მ(ო)წ(ამისაჲ).

1 March. In the Holy Anastasis, Silvester, the great patriarch of Rome and Paul and Germana [=Iouliana?] the saints, and martyr Eudokia.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
sj-pdf-1-ijo-10.1177_0306624X21990811 – Supplemental material for Exploring the Correspondence Between General Correctional Programming and Inmate Misconduct Using a Time-Course Framework
Creators: name: Linning, Shannon J.
name: Silver, Ian A.
name: Papp, Jordan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-pdf-1-ijo-10.1177_0306624X21990811 for Exploring the Correspondence Between General Correctional Programming and Inmate Misconduct Using a Time-Course Framework by Shannon J. Linning, Ian A. Silver and Jordan Papp in International Journal of Offender Therapy and Comparative Criminology
E03666: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 2 March Germana (an unidentified saint, possibly a corruption of some other name), Theokritos (also unidentified), and *Eutropios (perhaps the martyr of Pontus, S01152).
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: ბ. წ(მიდ)ისა გერმ(ა)ნაჲსი, და თეოკრიტო წ(მიდ)ისაჲ, და ევტროპი მ(ო)წ(ა)მ(ი)ს(ა)ჲ.

2 March. Saint 'Germane', saint Theokritos and martyr Eutropios.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
Non-inflammatory macrophages phagocytose and hydrolyse monosodium urate crystals in different stages of gout
Creators: name: Huang, Y-J
name: Wang, L-C
name: Wang, C-P
name: Yu, K-H
name: Kuo, C-F
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Physiology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology

description: Macrophages play a crucial role in gouty arthritis; however, the relationship between non-inflammatory macrophages (M0) and different stages of gout remains unclear. This study aimed to investigate the phagocytosis, hydrolysis, and subsequent cytokine secretion of monosodium urate (MSU) by non-inflammatory macrophages in patients in different stages of gout. Non-inflammatory macrophages were derived from monocytes through stimulation with macrophage colony-stimulating factor (M-CSF) for a duration of 10 days. The study included patients with asymptomatic hyperuricaemia, intercritical gout, tophaceous gout, and a normal control group. The phagocytic and hydrolytic capabilities of non-inflammatory macrophages were measured using flow cytometry based on the increase in side-scatter area. In addition, to evaluate the relationship between the hydrolysis capability of non-inflammatory macrophages and subsequent inflammation, we cultured them with lipopolysaccharide (LPS) and/or MSU. We discovered that M0 macrophages were capable of phagocytosing and hydrolysing MSU crystals in various stages of gout, including the control group. Patients with asymptomatic hyperuricaemia exhibited the most pronounced phagocytic and hydrolytic capabilities, surpassing even those of the normal control group. The presence of MSU alone did not induce the secretion of pro-inflammatory cytokines. However, in experiments where M0 macrophages were stimulated with LPS and/or MSU, the phagocytic and hydrolytic abilities of M0 macrophages were correlated with inflammatory cytokine elevation. The efficient phagocytosis and hydrolysis of MSU crystals by M0 macrophages suggest their role in maintaining the non-inflammatory stage of gout. Our findings suggest that non-inflammatory macrophages play a role in gout.
Supplemental Material, sj-docx-1-cat-10.1177_1076029620987900 - Evaluation of Direct Oral Anticoagulant Prescribing in Patients With Moderate to Severe Renal Impairment
Creators: name: Ting, Clara
name: Rhoten, Megan
name: Dempsey, Jillian
name: Nichols, Hunter
name: Fanikos, John
name: Ruff, Christian T.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental Material, sj-docx-1-cat-10.1177_1076029620987900 for Evaluation of Direct Oral Anticoagulant Prescribing in Patients With Moderate to Severe Renal Impairment by Clara Ting, Megan Rhoten, Jillian Dempsey, Hunter Nichols, John Fanikos and Christian T. Ruff in Clinical and Applied Thrombosis/Hemostasis
Additional file 12 of Identification of RimR2 as a positive pathway-specific regulator of rimocidin biosynthesis in Streptomyces rimosus M527
Creators: name: Li, Huijie
name: Hu, Yefeng
name: Zhang, Yongyong
name: Ma, Zheng
name: Bechthold, Andreas
name: Yu, Xiaoping
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 12: Figure S11. Detection and comparison of antifungal activities of WT strain M527, recombinant strains M527-R1, M527-R2, M527-R3, and M527-R4 against F. oxysporum f. sp. cucumerinum. Spore suspension (500 μl) of F. oxysporum f. sp. cucumerinum (1×106 cfu ml-1) was spread and inoculated on PDA medium at 28 °C for 1 d. A agar block (4 mm in diameter) containing actively growing WT strain M527, three random recombinant strains M527-R1(a), M527-R2(b), M527-R3(c), and M527-R4(d) was aseptically placed on aforementioned PDA medium containing pathogenic fungus at 28 °C for 3-4 d. The diameter of inhibition zone was measured as antagonistic activity. Plant-pathogenic fungus F. oxysporum f. sp. cucumerinum was used as indicator strain in antifungal activities assay.
Supplemental Material, sj-pdf-1-cat-10.1177_1076029621989813 - Brain-Derived Neurotrophic Factor, a New Predictor of Coronary Artery Calcification
Creators: name: Jin, Hong
name: Ji, Jing-jing
name: Zhu, Yi
name: Wang, Xiao-dong
name: Li, Yi-ping
name: Shi, Qiu-yin
name: Chen, Yi-fei
Publisher: name: SAGE Journals
Year: 2021
Subjects: Cardiology
Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental Material, sj-pdf-1-cat-10.1177_1076029621989813 for Brain-Derived Neurotrophic Factor, a New Predictor of Coronary Artery Calcification by Hong Jin, Jing-jing Ji, Yi Zhu, Xiao-dong Wang, Yi-ping Li, Qiu-yin Shi and Yi-fei Chen in Clinical and Applied Thrombosis/Hemostasis
Sex differences in treatment response in patients with rheumatoid arthritis treated with tumour necrosis factor inhibitor: a cohort study from the DANBIO registry
Creators: name: Lauridsen, KB
name: Duch, KS
name: Mortensen, AS
name: Cordtz, R
name: Kristensen, S
name: Lund, M L
name: Dreyer, LW
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: The aim of this study was to investigate associations between sex and treatment response and persistence in patients with rheumatoid arthritis (RA) initiating their first tumour necrosis factor inhibitor (TNFi). This Danish nationwide cohort study included RA-patients starting their first TNFi treatment between 2006 and 2022. Overall and age-specific treatment response was compared across sexes at 4 and 12 months. Treatment persistence was investigated using survival analysis. In total, 7789 RA-patients were identified; 75% were females. Females had slightly smaller ∆DAS28-CRP compared to males after 12 months, mainly due to less reduction of swollen joint count (SJC) and CRP. At 12 months the crude proportion of males with good response was higher (62%) than in females (55%), adjusted RR 1.14 (95% confidence interval (CI) 1.06; 1.23). The adjusted hazard ratio for treatment termination within first year was 0.82 (95% CI 0.73; 0.92) in males versus females. The median treatment persistence for individuals aged <50 years was 1.6 years (95% CI 1.4; 1.8) in females and 3.2 years (95% CI 2.6; 4.0) in males. The same difference was not seen in patients aged > 50 years. Despite similar baseline disease activity, females had a lower chance than males of achieving good response 4 and 12 months after starting treatment with first TNFi. The sex difference in DAS28-CRP improvement is caused by a greater decrease in CRP and SJC among males. Further, females had an increased risk of discontinuation, especially among patients aged < 50 years.
E03667: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 3 March*Eutropios and Kleonikos, and *Basiliskos (martyrs of Pontus, S01152 and S00388), *Adrianos and Natalia (martyr of Nicomedia and his pious wife, S01342), *Agapios (probably the martyr in Palestine, S00188), *Gerasimos (anchorite, founder of a monastery in the Judean desert, S01507), and *Porphyrios (bishop of Gaza, ob. 420, S01368).
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: გ. კლეონიკოჲსი და ევდოროპისი და ბასილიკესი, და ანდრია\ნესი და ცოლისა მისისა ანატოლესი, და აღაპისი მ(ა)რტ(ჳ)ლის(ა), და ჯერასიმესი, და პორფირი ეპ(ის)კ(ოპოსი)ს(ა)ჲ.

3 March. Saints Kleonikos and Eutropios and Basiliskos, Adrianos and his wife 'Anatolia' [=Natalia], martyr Agapios and Gerasimos and Bishop Porphyrios.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
sj-pdf-1-mdm-10.1177_0272989X21990371 – Supplemental material for Adaptive Policies to Balance Health Benefits and Economic Costs of Physical Distancing Interventions during the COVID-19 Pandemic
Creators: name: Yaesoubi, Reza
name: Havumaki, Joshua
name: Chitwood, Melanie H.
name: Menzies, Nicolas A.
name: Gonsalves, Gregg
name: Salomon, Joshua A.
name: A. David Paltiel
name: Cohen, Ted
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-mdm-10.1177_0272989X21990371 for Adaptive Policies to Balance Health Benefits and Economic Costs of Physical Distancing Interventions during the COVID-19 Pandemic by Reza Yaesoubi, Joshua Havumaki, Melanie H. Chitwood, Nicolas A. Menzies, Gregg Gonsalves, Joshua A. Salomon, A. David Paltiel and Ted Cohen in Medical Decision Making
Supplementary Figures - Supplemental material for Two New Compounds From the Heartwood of Dalbergia melanoxylon and Their Protective Effect on Hypoxia/Reoxygenation Injury in H9c2
Creators: name: Liu, Yang
name: Zhang, Ni
name: He, Jun-wei
name: Chen, Lan-ying
name: Yang, Li
name: Meng, Xiao-wei
name: Shao, Feng
name: Liu, Rong-hua
Publisher: name: SAGE Journals
Year: 2021
Subjects: Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, Supplementary Figures, for Two New Compounds From the Heartwood of Dalbergia melanoxylon and Their Protective Effect on Hypoxia/Reoxygenation Injury in H9c2 by Yang Liu, Ni Zhang, Jun-wei He, Lan-ying Chen, Li Yang, Xiao-wei Meng, Feng Shao and Rong-hua Liu in Natural Product Communications
E03668: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 4 March *Kosmas and Damianos (brothers, physician martyrs of Syria, S00385), *Euboulos from Batanaea (martyr of Palestine, S00166) and *Hesychios (martyr in Antioch, S01034).
Creators: name: Naleksidze
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: დ. წ(მიდა)თა კოზმან დამიანესი, და ევპოლაჲსი მ(ო)წ(ა)მ(ი)\ს(ა)ჲ, და ევსუქი ხუცის(ა)ჲ.

4 March. Saints Kosmas and Damianos and martyr Euboulos and priest Hesychios.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
E03669: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 5 March *Andrew (the Apostle, S00288), *Gerasimos (anchorite, founder of a monastery in the Judean desert, S01507), and, as a later addition, Theodore 'the neo-martyr', one of a group of martyrs killed by the Arabs in 838.
Creators: name: Naleksidze
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: ე. ანდრია მ(ო)ც(ი)ქ(უ)ლის(ა)ჲ, და ჯერასიმისიმის(ა)ჲ, და თ(ევდორ)ე მ(ო)წ(ა)მ(ი)ს(ა)ჲ ახლის(ა)ჲ და მოყ(უა)სთაჲ.

5 March. Apostle Andrew and Gerasimos and Theodore the neo-martyr and his companions.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
E03670: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 6 March *Agapios (probably the martyr in Palestine, S00188), *Adrianos and Euboulos from Batanaea (martyrs of Palestine, S00166), and *Konon (gardener and martyr of Magydos of Pamphilia, S00177).
Creators: name: Naleksidze
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: ვ. წ(მი)დისა აგაპისი და ანდრიანჱსი და ევბულჱსი წ(მიდა)\თ(ა)ჲ, და კონონისი.

6 March. Saint Agapios and saints Adrianos and Euboulos and Konon.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
Additional file 3 of Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction
Creators: name: Kundik, Arkadi
name: Musimbi, Zaneta D.
name: Krücken, Jürgen
name: Hildebrandt, Thomas
name: Kornilov, Oleg
name: Hartmann, Susanne
name: Ebner, Friederike
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: Computational Biology

description: Additional file 3: Figure S3. Impact of methanol (MeOH) on metabolic activity of A. suum L3. Larvae (500 L3/96-well) were exposed for 3 h to different concentrations (v/v) of MeOH, and the relative fluorescence intensity of resorufin was measured after incubation with 7.5 µg/ml resazurin for 24 h. Four-parameter logistic regression analysis on log10-transformed MeOH concentration was used to interpolate dose response curve (solid black line; df = 26, R2 = 0.95). Best-fit EC50 = 6.8% (95% CI = 4.3–9.2%). Black dots represent arithmetic means, and whiskers correspond to the standard deviation of n = 3 technical replicates. Coordinates plotted using base-2 logarithmic scale on the x-axis and linear scale on the y-axis.
title: Das Zinnowitzlied: Ein Symbol des Bäder-Antisemitismus
Creators: name: Bajohr, Frank
Publisher: name: Institut für die Geschichte der deutschen Juden
Year: 2016
Subjects: subject: Judenfeindschaft und Verfolgung

description: Die Postkarte wurde in den Andenkenläden in Zinnowitz zusammen mit
den sonst üblichen Ansichtskarten verkauft. Antisemitisch
eingestellte Gäste konnten sie als Feriengruß an Gleichgesinnte
versenden oder sie zum Mitsingen verwenden, wenn die Kurkapelle von
Zinnowitz das Lied als Abschluss jedes Konzertes intonierte.

Der Verfasser des Liedes ist unbekannt, die Initialen „H. Gr.“ auf
der Postkarte sind nicht eindeutig aufzulösen. Die Postkarte mit dem
„Zinnowitzlied“ wurde im Jahre 1922 auch dem „Centralverein
deutscher Staatsbürger jüdischen Glaubens“ zugeleitet, der in
seinen Beständen eine eigene Akte über das Ostseebad Zinnowitz
(Insel Usedom) führte. Die erhalten gebliebenen Akten des
Centralvereins befinden sich heute im Sonderarchiv Moskau. Sie liegen
auch als Mikrofilm-Kopie in den Central Archives for the History of
the Jewish People in Jerusalem vor (Kopie der Postkarte im Bestand CV,
Akte 2405). Die hier veröffentlichte Abbildung der Postkarte wurde
der DVD-Sammlung „Spott und Hetze. Antisemitische Postkarten
1893–1945. Aus der Sammlung Wolfgang Haney“ (Berlin 2008)
entnommen.
title: The Zinnowitz Song: A Symbol of Resort Antisemitism
Creators: name: Bajohr, Frank
Publisher: name: Institute for the History of the German Jews
Year: 2016
Subjects: subject: Antisemitism and Persecution

description: This postcard was sold in souvenir shops in the Baltic resort of
Zinnowitz alongside the usual souvenir postcards. Tourists of an
antisemitic bent could send them to likeminded people as a greeting or
use it to sing along when the Zinnowitz resort band played the song at
the finale of each concert.
The songwriter is unknown, and it is uncertain what the initials “H.
Gr.” on the postcard stand for. In 1922, a postcard featuring the
“Zinnowitz song” was forwarded to the “Centralverein deutscher
Staatsbürger jüdischen Glaubens” [Central Association of German
Citizens of the Jewish Faith], which kept a file on the Baltic resort
of Zinnowitz (island of Usedom). Today the Centralverein’s surviving
files are located at the Osobyi Arkhiv (Special Archive) in Moscow.
There also is a microfiche copy at the Central Archives for the
History of the Jewish People in Jerusalem (a copy of the postcard is
filed in the CV holdings, file no. 2405). This image of the postcard
was taken from a DVD collection titled “Spott und Hetze.
Antisemitische Postkarten 1893-1945. Aus der Sammlung Wolfgang
Haney” (Berlin, 2008).
Additional file 1 of Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction
Creators: name: Kundik, Arkadi
name: Musimbi, Zaneta D.
name: Krücken, Jürgen
name: Hildebrandt, Thomas
name: Kornilov, Oleg
name: Hartmann, Susanne
name: Ebner, Friederike
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: Computational Biology

description: Additional file 1: Figure S1. Unsheathed A. suum L3 ingest fluorescein-conjugated bovine serum albumin (FITC-BSA). Strong fluorescence is exhibited from a the midgut (left) and the oral opening (right). b L3 carrying an intact sheath (left, indicated by black arrowhead) do not exhibit fluorescence (right). Image acquisition settings: λex = 475 nm with a bandpass filter for λem = 500–525 nm. White scale bar: 20 µm. Yellow scale bar: 40 µm.
sj-pdf-1-cre-10.1177_0269215521992473 – Supplemental material for Liuzijue qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory control: Results of a single-center randomized controlled trial
Creators: name: Wang, Jie
name: Li, Gaiyan
name: Ding, Shanshan
name: Yu, Long
name: Wang, Yan
name: Qiao, Lei
name: Wu, Qilin
name: Ni, Weidong
name: Fan, Hang
name: Zheng, Qianyun
name: Zhang, Ying
name: Li, Hongli
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Orthopaedics
subject: Sports Medicine

description: Supplemental material, sj-pdf-1-cre-10.1177_0269215521992473 for Liuzijue qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory control: Results of a single-center randomized controlled trial by Jie Wang, Gaiyan Li, Shanshan Ding, Long Yu, Yan Wang, Lei Qiao, Qilin Wu, Weidong Ni, Hang Fan, Qianyun Zheng, Ying Zhang and Hongli Li in Clinical Rehabilitation
Additional file 4 of Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction
Creators: name: Kundik, Arkadi
name: Musimbi, Zaneta D.
name: Krücken, Jürgen
name: Hildebrandt, Thomas
name: Kornilov, Oleg
name: Hartmann, Susanne
name: Ebner, Friederike
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: Computational Biology

description: Additional file 4: Table S1. Maximum soluble concentrations of ivermectin, mebendazole, and thiabendazole in 0.5% DMSO determined by turbidimetric solubility assay.
sj-pdf-1-cre-10.1177_0269215521990950 – Supplemental material for Effects of electromyographic biofeedback interventions for shoulder pain and function: Systematic review and meta-analysis
Creators: name: Kamonseki, Danilo Harudy
name: Calixtre, Letícia Bojikian
name: Barreto, Rodrigo Py Gonçalves
name: Camargo, Paula Rezende
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-1-cre-10.1177_0269215521990950 for Effects of electromyographic biofeedback interventions for shoulder pain and function: Systematic review and meta-analysis by Danilo Harudy Kamonseki, Letícia Bojikian Calixtre, Rodrigo Py Gonçalves Barreto and Paula Rezende Camargo in Clinical Rehabilitation
Additional file 2 of Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction
Creators: name: Kundik, Arkadi
name: Musimbi, Zaneta D.
name: Krücken, Jürgen
name: Hildebrandt, Thomas
name: Kornilov, Oleg
name: Hartmann, Susanne
name: Ebner, Friederike
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: Computational Biology

description: Additional file 2: Figure S2. Fluorescence emission spectra of resorufin diluted in H2O and 25% methanol (MeOH) at 540 nm. The dashed black curve (peak at 585 nm) represents the measured emission spectrum of resorufin diluted in H2O, and the solid black curve (peak at 587 nm) represents the measured emission spectra of resorufin diluted in 25% MeOH.
sj-pdf-4-cre-10.1177_0269215521990950 – Supplemental material for Effects of electromyographic biofeedback interventions for shoulder pain and function: Systematic review and meta-analysis
Creators: name: Kamonseki, Danilo Harudy
name: Calixtre, Letícia Bojikian
name: Barreto, Rodrigo Py Gonçalves
name: Camargo, Paula Rezende
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-4-cre-10.1177_0269215521990950 for Effects of electromyographic biofeedback interventions for shoulder pain and function: Systematic review and meta-analysis by Danilo Harudy Kamonseki, Letícia Bojikian Calixtre, Rodrigo Py Gonçalves Barreto and Paula Rezende Camargo in Clinical Rehabilitation
E03671: The Church Calendar of Ioane Zosime, compiled in Georgian in the 10th century, based however on 5th-7th c. prototypes from Jerusalem, commemorates on 7 March *Arkadios (S01378) and *Nestor (S01379), bishops and martyrs in Cyprus, *Pionios (presbyter and martyr in Smyrna, S00031), and, as a later addition, Bishop Theophylaktos of Antioch, confessor under the iconoclast emperor Leo V the Armenian (813-820).
Creators: name: Naleksidze
Publisher: name: University of Oxford
Year: 2017
Subjects: History

description: ზ. წ(მიდა)თა მამათა ჩ(უე)ნთაჲ კჳპრელ ეპ(ის)კ(ოპოსი)ს(ა)ჲ არკატისი და ნესთერეოჲსი, და წ(მიდ)ისა პინოჲსი, წ(მიდა)თაჲ, და თეოფილკტე ეპ(ის)კ(ოპოსი)ს(ა)ჲ.

7 March. Our holy fathers, Cypriot bishops Arkadios and Nestor and saint Pionios and bishop Theophylaktos.

Text: Garitte 1958, 53-57; Electronic text: Gippert 2017, http://titus.uni-frankfurt.de/texte/etcg/cauc/ageo/liturg/iozosca2/iozos.htm (26.12.17); Translation: N. Aleksidze.
Nanovector approach for co-delivery of Alectinib and Hesperidin via inhalational for lung cancer treatment: development, characterization, and preclinical studies
Creators: name: Ahmad, Saeem
name: Bano, Shahnaj
name: Emad, Nasr A.
name: Alam, Shadab
name: Rathee, Anjali
name: Zai, Iqra
name: Pandit, Jayamanti
name: Aqil, Mohd
name: Sultana, Yasmin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: The current study aims to fabricate Nanostructured Lipid Carriers for the co-delivery of Alectinib and Hesperidin (ALB-HSD NLC) for non-small cell lung Cancer (NSCLC) via an inhalational route. The ALB-HSD NLC was fabricated using Melt emulsification followed by the sonication method and optimized using a central composite design. The optimized formulation was evaluated for various in vitro and in vivo studies. The optimized ALB-HSD NLC had satisfactory results for particle size, Zeta Potential, PDI, and entrapment efficiency. The drug release was more than 2.5-fold higher compared to drugs suspension over 72 hr. A549 human lung cell line study shows IC50 for ALB and HSD, were 2.289 µg/mL and 73.52 µg/mL, and the dose-dependent toxicity was 0.0209 μg/mL and 0.5213 μg/mL for ALB-HSD NLC formulation and ALB HSD Suspension, respectively, after 72 hr. The Pharmacokinetic study has demonstrated improved AUC0-t (1.38, 1.57-fold) of ALB and HSD from NLC compared to drug suspension. In vivo studies give significant results on the syngeneic model. The prepared ALB-HSD NLC could be promising drug carriers, and they succeeded in delivering small and efficient doses of ALB and HSD to treat NSCLC.
sj-docx-1-jop-10.1177_0269881120985147 – Supplemental material for Role of nitric oxide signaling in the antidepressant mechanism of action of ketamine: A randomized controlled trial
Creators: name: Bevilacqua, Laura
name: Charney, Alex
name: Pierce, Charlotte R
name: Richards, Samantha M
name: Jha, Manish K
name: Glasgow, Andrew
name: Brallier, Jess
name: Kirkwood, Katherine
name: Bagiella, Emilia
name: Charney, Dennis S
name: Murrough, James W
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, sj-docx-1-jop-10.1177_0269881120985147 for Role of nitric oxide signaling in the antidepressant mechanism of action of ketamine: A randomized controlled trial by Laura Bevilacqua, Alex Charney, Charlotte R Pierce, Samantha M Richards, Manish K Jha, Andrew Glasgow, Jess Brallier, Katherine Kirkwood, Emilia Bagiella, Dennis S Charney and James W Murrough in Journal of Psychopharmacology
Supplemental Material, sj-pdf-1-ear-10.1177_0145561320986060 - Comparison of the Cerumenolytic Activities of New and Currently Used Agents
Creators: name: Anh, Nguyen Quynh
name: Numthavaj, Pawin
name: Bhongmakapat, Thongchai
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental Material, sj-pdf-1-ear-10.1177_0145561320986060 for Comparison of the Cerumenolytic Activities of New and Currently Used Agents by Nguyen Quynh Anh, Pawin Numthavaj and Thongchai Bhongmakapat in Ear, Nose & Throat Journal