cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
How planets grow by pebble accretion II: Analytical calculations on the evolution of polluted envelopes
Creators: name: Brouwers, M. G.
name: Ormel, C. W.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Proto-planets embedded in their natal disks acquire hot envelopes as they grow and accrete solids. This ensures that the material they accrete - pebbles, as well as (small) planetesimals - will vaporize to enrich their atmospheres. Enrichment modifies an envelope's structure and significantly alters its further evolution. Our aim is to describe the formation of planets with polluted envelopes from the moment that impactors begin to sublimate to beyond the disk's eventual dissipation. We constructed an analytical interior structure model, characterized by a hot and uniformly mixed high-Z vapor layer surrounding the core, located below the usual unpolluted radiative-convective regions. The evolution of planets with uniformly mixed polluted envelopes follows four potential phases. Initially, the central core grows directly through impacts and rainout until the envelope becomes hot enough to vaporize and absorb all incoming solids. We find that a planet reaches runaway accretion when the sum of its core and vapor mass exceeds a value that we refer to as the critical metal mass - a criterion that supersedes the traditional critical core mass. It scales positively with both the pollutant's evaporation temperature and with the planet's core mass. Hence, planets at shorter orbital separations require the accretion of more solids to reach runaway as they accrete less volatile materials. If the solids accretion rate dries up, we identify the decline of the mean molecular weight - dilution - as a mechanism to limit gas accretion during a polluted planet's embedded cooling phase. When the disk ultimately dissipates, the envelope's inner temperature declines and its vapor eventually rains out, augmenting the mass of the core. The energy release that accompanies this does not result in significant mass-loss, as it only occurs after the planet has substantially contracted.
description: 18 pages, 11 figures. Published in A&A
Neutron beam test of CsI crystal for dark matter search
Creators: name: Park, H.
name: Choi, D. H.
name: Hahn, I. S.
name: Hwang, M. J.
name: Kang, W. G.
name: Kim, H. J.
name: Kim, J. H.
name: Kim, S. C.
name: Kim, S. K.
name: Kim, T. Y.
name: Kim, Y. D.
name: Kwon, Y. J.
name: Lee, H. S.
name: Lee, J. H.
name: Lee, M. H.
name: Lee, S. E.
name: Noh, S. H.
name: Park, I. H.
name: Seo, E. S.
name: Won, E.
name: Yang, H. Y.
name: Yang, M. S.
name: Yu, I.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We have studied the response of Tl-doped and Na-doped CsI crystals to nuclear recoils and $γ$'s below 10 keV. The response of CsI crystals to nuclear recoil was studied with mono-energetic neutrons produced by the $^3$H(p,n)$^3$He reaction. This was compared to the response to Compton electrons scattered by 662 keV $γ$-ray. Pulse shape discrimination between the response to these $γ$'s and nuclear recoils was studied, and quality factors were estimated. The quenching factors for nuclear recoils were derived for both CsI(Na) and CsI(Tl) crystals.
description: 21pages, 14figures, submitted to NIMA
MOESM1 of The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS
Creators: name: J. Wells
name: Dongqi Xing
name: Viera, Liliana
name: Burkes, Robert
name: Yixin Wu
name: Bhatt, Surya
name: Dransfield, Mark
name: Couper, David
name: Oâ€™Neal, Wanda
name: Hoffman, Eric
name: Gaggar, Amit
name: Barjaktarevic, Igor
name: Curtis, Jeffrey
name: Labaki, Wassim
name: Han, Mei
name: Freeman, Christine
name: Nirupama Putcha
name: Schlange, Thomas
name: J. Blalock
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Supplementary Methods. Figure S1. CONSORT Diagram.
Quantum random walks in one dimension
Creators: name: Konno, Norio
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: This letter treats the quantum random walk on the line determined by a 2 times 2 unitary matrix U. A combinatorial expression for the mth moment of the quantum random walk is presented by using 4 matrices, P, Q, R and S given by U. The dependence of the mth moment on U and initial qubit state phi is clarified. A new type of limit theorems for the quantum walk is given. Furthermore necessary and sufficient conditions for symmetry of distribution for the quantum walk is presented. Our results show that the behavior of quantum random walk is striking different from that of the classical ramdom walk.
description: 9 pages, journal reference added
High-intensity exercise mitigates cardiovascular deconditioning during long-duration bed rest
Creators: name: Maggioni, Martina A.
name: Castiglioni, Paolo
name: Merati, Giampiero
name: Brauns, Katharina
name: Gunga, Hanns-Christian
name: Mendt, Stefan
name: Opatz, Oliver S.
name: Rundfeldt, Lea C.
name: Steinach, Mathias
name: Werner, Anika
name: Stahn, Alexander C.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: heart rate variability
subject: hemodynamics
subject: countermeasure
subject: cardiovascular deconditioning
subject: posture
subject: long-term bed rest
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Head-down-tilt bed rest (HDT) mimics the changes in hemodynamics and autonomic cardiovascular control induced by weightlessness. However, the time course and reciprocal interplay of these adaptations, and the effective exercise protocol as a countermeasure need further clarification. The overarching aim of this work (as part of a European Space Agency sponsored long-term bed rest study) was therefore to evaluate the time course of cardiovascular hemodynamics and autonomic control during prolonged HDT and to assess whether high-intensity, short-duration exercise could mitigate these effects. A total of n = 23 healthy, young, male participants were randomly allocated to two groups: training (TRAIN, n = 12) and non-training (CTRL, n = 11) before undergoing a 60-day HDT. The TRAIN group underwent a resistance training protocol using reactive jumps (5-6 times per week), whereas the CTRL group did not perform countermeasures. Finger blood pressure (BP), heart rate (HR), and stroke volume were collected beat-by-beat for 10min in both sitting and supine positions 7 days before HDT (BDC-7) and 10 days after HDT (R+10), as well as on the 2nd (HDT2), 28th (HDT28), and 56th (HDT56) day of HDT. We investigated (1) the isolated effects of long-term HDT by comparing all the supine positions (including BDC-7 and R+10 at 0 degrees), and (2) the reactivity of the autonomic response before and after long-term HDT using a specific postural stimulus (i.e., supine vs. sitting). Two-factorial linear mixed models were used to assess the time course of HDT and the effect of the countermeasure. Starting from HDT28 onwards, HR increased (p < 0.02) and parasympathetic tone decreased exclusively in the CTRL group (p < 0.0001). Moreover, after 60-day HDT, CTRL participants showed significant impairments in increasing cardiac sympathovagal balance and controlling BP levels during postural shift (supine to sitting), whereas TRAIN participants did not. Results show that a 10-day recovery did not compensate for the cardiovascular and autonomic deconditioning following 60-day HDT. This has to be considered when designing rehabilitation programs-not only for astronauts but also in general public healthcare. High-intensity, short-duration exercise training effectively minimized these impairments and should therefore deserve consideration as a cardiovascular deconditioning countermeasure for spaceflight.
Quantum Spectrum for a Kerr-Newman Black Hole
Creators: name: Gour, Gilad
name: Medved, A. J. M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, we consider the quantum area spectrum for a rotating and charged (Kerr-Newman) black hole. Generalizing a recent study on Kerr black holes (which was inspired by the static-black hole formalism of Barvinsky, Das and Kunstatter), we show that the quantized area operator can be expressed in terms of three quantum numbers (roughly related to the mass, charge and spin sectors). More precisely, we find that $A=8π\hbar[n+{1\over 2}+{p_1\over 2}+p_2]$, where $n$, $p_1$ and $p_2$ are strictly non-negative integers. In this way, we are able to confirm a uniformly spaced spectrum even for a fully general Kerr-Newman black hole. Along the way, we derive certain selection rules and use these to demonstrate that, in spite of appearances, the charge and spin spectra are not completely independent.
description: 13 pages, Revtex
Dashen's Phenomenon in Gauge Theories with Spontaneously Broken Chiral Symmetries
Creators: name: Akemann, G.
name: Lenaghan, J. T.
name: Splittorff, K.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We examine Dashen's phenomenon in the Leutwyler--Smilga regime of QCD with any number of colors and quarks in either the fundamental or adjoint representations of the gauge group. In this limit, the theories only depend on simple combinations of quark masses, volume, chiral condensate and vacuum angle. Based upon this observation, we derive simple expressions for the chiral condensate and the topological density and show that they are in fact related. By examining the zeros of the various partition functions, we elucidate the mechanism leading to Dashen's phenomena in QCD.
description: 5 pages, revtex, references added, version to appear in PRD
Toxomerus minutus
Creators: name: Borges, Zuleica M.
name: Couri, Marcia S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Toxomerus
Toxomerus minutus

description: Toxomerus minutus (Wiedemann)
 Syrphus minutus Wiedemann, 1830: 146 (descr.); Williston, 1886: 312 (cat.).
 Mesogramma minuta Schiner, 1868: 347.
 Mesograpta minuta Osten Sacken, 1875: 49 (cat.)
 Toxomerus minutus Kertész, 1910: 148 (cat.& n.comb.); Thompson et al., 1976: 52 (cat.); Thompson, 1981: 102.
 Diagnosis. Scutum black except yellow laterally; scutellum yellow. Pro and mesofemora yellow, metafemur yellow with black annulus; tibiae yellow. Abdomen yellow with posterior borders of all terga brown. Length. Body 5.0 mm.
 Discussion. The characters presented here are based on the original description because no specimens was examined. Although the diagnosis very brief, it suggests some color similarities with T. duplicatus. Some notes from Cuba and Puerto Rico refer to T. watsoni or T. difficilis (Thompson 1981).
 Geographical record. Central America to South America.
description: Published as part of Borges, Zuleica M. & Couri, Marcia S., 2009, Revision of Toxomerus Macquart, 1855 (Diptera: Syrphidae) from Brazil with synonymic notes, identification key to the species and description of three new species 2179, pp. 1-72 in Zootaxa 2179 on page 41
Riconoscimento e disconoscimento, tra provvidenzialismo e probabilismo: per una introduzione al “pensiero coloniale” antropologico nell’America Latina del XVII secolo.
Creators: name: Ponzio, Paolo
Publisher: name: Post-filosofie
Year: 2020
Subjects: provvidenzialismo; probabilismo; pensiero coloniale; America Latina del XVII secolo

description: Leon Pinelo e Diego de Avendaño rappresentano due tra gli autori più significativi del panorama filosofico del XVII secolo peruviano che, in stretta continuità con le posizioni di avanguardia della seconda scolastica, ripensano il rapporto tra spagnoli e popolazione indigena cercando di equilibrare le esigenze della politica spagnola di controllo di una società multietnica con le istanze etiche della popolazione nativa. Questo è il motivo per il quale il ricorso al provvidenzialismo da una parte e al probabilismo dall’altro, garantiva un contrappeso preciso a ogni prevaricazione, l’unica sintesi possibile nel lungo processo di riconoscimento dell’altro. Leon Pinelo and Diego de Avendaño represent two of the most significant authors of the 17th century Peruvian philosophical panorama who, in close continuity with the avant-garde positions of the second school, rethink the relationship between Spaniards and indigenous people trying to balance the needs of Spanish politics of control of a multiethnic society with the ethical demands of the native population. This is the reason why the use of providentialism on the one hand and probabilism on the other, guaranteed a precise counterweight to every abuse, the only possible synthesis in the long process of recognition of the other.
description: Post-filosofie, N. 12 (2019): Anno 12. Numero12. Le rivoluzioni dell’alterità
Polarization transfer in the $^{16}$O$(p,p')$ reaction at forward angles and structure of the spin-dipole resonances
Creators: name: Kawabata, T.
name: Akimune, H.
name: Berg, G. P. A.
name: Fujimura, H.
name: Fujita, H.
name: Fujita, Y.
name: Fujiwara, M.
name: Hara, K.
name: Hatanaka, K.
name: Hosono, K.
name: Ishikawa, T.
name: Itoh, M.
name: Kamiya, J.
name: Nakamura, M.
name: Noro, T.
name: Obayashi, E.
name: Sakaguchi, H.
name: Shimbara, Y.
name: Takeda, H.
name: Taki, T.
name: Tamii, A.
name: Toyokawa, H.
name: Uchida, M.
name: Ueno, H.
name: Wakasa, T.
name: Yamasaki, K.
name: Yasuda, Y.
name: Yoshida, H. P.
name: Yosoi, M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Cross sections and polarization transfer observables in the $^{16}$O$(p,p')$ reactions at 392 MeV were measured at several angles between $θ_{lab}=$ 0$^\circ$ and 14$^\circ$. The non-spin-flip ($ΔS=0$) and spin-flip ($ΔS=1$) strengths in transitions to several discrete states and broad resonances in $^{16}$O were extracted using a model-independent method. The giant resonances in the energy region of $E_x=19-$27 MeV were found to be predominantly excited by $ΔL=1$ transitions. The strength distribution of spin-dipole transitions with $ΔS=1$ and $ΔL=1$ were deduced. The obtained distribution was compared with a recent shell model calculation. Experimental results are reasonably explained by distorted-wave impulse approximation calculations with the shell model wave functions.
description: 28 pages RevTex, including 9 figures, to be published in Phys. Rev. C.; a typo in Eq. (3b) was corrected
Differences in stress-induced modulation of the auditory system between Wistar and Lewis rats
Creators: name: Szczepek, Agnieszka J.
name: Dietz, Gunnar P. H.
name: Reich, Uta
name: Hegend, Olga
name: Olze, Heidi
name: Mazurek, Birgit
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: auditory perception
subject: auditory threshold
subject: DPOAE
subject: auditory brainstem response
subject: stress
subject: psychological
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Many aspects of stress-induced physiological and psychological effects have been characterized in people and animals. However, stress effects on the auditory system are less explored and their mechanisms are not well-understood, in spite of its relevance for a variety of diseases, including tinnitus. To expedite further research of stress-induced changes in the auditory system, here we compare the reactions to stress among Wistar and Lewis rats. The animals were stressed for 24 h, and subsequently we tested the functionality of the outer hair cells (OHCs) using distortion product otoacoustic emissions (DPOAEs) and auditory neurons using evoked auditory brainstem responses (ABR). Lastly, using Western blot, we analyzed the levels of plasticity-related proteins in the inferior colliculus, confirming that the inferior colliculus is involved in the adaptive changes that occur in the auditory system upon stress exposure. Surprisingly, the two strains reacted to stress quite differently: Lewis rats displayed a lowering of their auditory threshold, whereas it was increased in Wistar rats. These functional differences were seen in OHCs of the apical region (low frequencies) and in the auditory neurons (across several frequencies) from day 1 until 2 weeks after the experimental stress ended. Wistar and Lewis rats may thus provide models for auditory threshold increase and decrease, respectively, which can both be observed in different patients in response to stress.
Mutual learning in a tree parity machine and its application to cryptography
Creators: name: Rosen-Zvi, Michal
name: Klein, Einat
name: Kanter, Ido
name: Kinzel, Wolfgang
Publisher: name: arXiv
Year: 2002
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Mutual learning of a pair of tree parity machines with continuous and discrete weight vectors is studied analytically. The analysis is based on a mapping procedure that maps the mutual learning in tree parity machines onto mutual learning in noisy perceptrons. The stationary solution of the mutual learning in the case of continuous tree parity machines depends on the learning rate where a phase transition from partial to full synchronization is observed. In the discrete case the learning process is based on a finite increment and a full synchronized state is achieved in a finite number of steps. The synchronization of discrete parity machines is introduced in order to construct an ephemeral key-exchange protocol. The dynamic learning of a third tree parity machine (an attacker) that tries to imitate one of the two machines while the two still update their weight vectors is also analyzed. In particular, the synchronization times of the naive attacker and the flipping attacker recently introduced in [1] are analyzed. All analytical results are found to be in good agreement with simulation results.
Cornelius Lanczos -- Discoveries in the Quantum and General Relativity Theories
Creators: name: Sachs, Mendel
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Two of Lanczos' seminal contributions in physics that are not generally known about in the physics community are discussed and commented in relation to more recent investigations: First, his integral formulation of the Schroedinger equation that he published just before Schroedinger himself published his differential equation formulation of quantum mechanics, and, second, his solution to the problem of equations of motion of material particles in the theory of general relativity.
description: 7 pages. To appear in Annales Fond. Louis de Broglie (2002)
"SIFAT MENEJMENTI TIZIMI SOHASIDA KONSALTING XIZMATLAR.
Creators: name: Samatov, Azizjon
Publisher: name: Zenodo
Year: 2024

description: Menejment tizimi sifati konsalting xizmatlari, tashkilotlarga boshqaruv jarayonlarini tizimliroq qilish, faollikni oshirish, vaqtni samarali ishlashni ta'minlashda yordam beradi. Bu xizmatlar tashkilot strukturasi, ish jarayonlari, tadbirlarni rivojlantirish, liderlikni o'rgatish, va boshqa menejment asoslari bo'yicha maslahatlar keng doirada o'z ichiga oladi. Konsaltinq kompaniyalari o'zlarini mustaqil observatorlar sifatida ta'kidlaydilar va tashkilotlarga eng yaxshi amaliyotlarni taklif etishda yordam bermoqda.
beadplexr: reproducible and automated analysis of multiplex bead assays
Creators: name: Stervbo, Ulrik
name: Westhoff, Timm H.
name: Babel, Nina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: ELISA
subject: R package
subject: Quality assessment
subject: Data analysis
subject: Multiplex bead assay
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Multiplex bead assays are an extension of the commonly used sandwich ELISA. The advantage over ELISA is that they make simultaneous evaluation of several analytes possible. Several commercial assay systems, where the beads are acquired on a standard flow cytometer, exist. These assay systems come with their own software tool for analysis and evaluation of the concentration of the analyzed analytes. However, these tools are either tied to particular commercial software or impose other limitations to their licenses, such as the number of events which can be analyzed. In addition, all these solutions are 'point and click' which potentially obscures the steps taken in the analysis. Here we present beadplexer, an open-source R-package for the reproducible analysis of multiplex bead assay data. The package makes it possible to automatically identify bead clusters, and provides functionality to easily fit a standard curve and calculate the concentrations of the analyzed analytes. beadplexer is available from CRAN and from https://gitlab.com/ustervbo/beadplexr.
Generation of Magnetic Fields in Cosmology
Creators: name: Dolgov, A. D.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Mechanisms of generation of magnetic fields in the early universe which could seed the present-day large scale galactic magnetic fields, are briefly reviewed. Three possible ways to create large scale magnetic fields are discussed: breaking of conformal invariance of electromagnetic interactions and inflationary stretching of the field wave length, first order cosmological phase transitions, and chaotic electric currents generated by turbulent flows in the primeval plasma.
description: 8 pages; to be published in Collection of papers dedicated to 70th anniversary of S.G. Matinyan a few references and discussion added
Dimeric hexylitaconic acids from the marine-derived fungus Aspergillus welwitschiae CUGBMF180262
Creators: name: Han, Jiahui
name: Yang, Na
name: Wei, Shangzhu
name: Jia, Jia
name: Lin, Rui
name: Li, Jiangpeng
name: Bi, Hongkai
name: Song, Fuhang
name: Xu, Xiuli
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: In the course of our efforts to search new secondary metabolites from marine-derived fungi, one new hexylitaconic acid derivative, 3-(5-methoxycarbonylpentyl)-4-methylfuran-2,5-dione (1), and two dimeric analogues asperwelwinates A and B (2 and 3), together with ten known compounds, asperitaconic acid C (4), kotanin (5) and orlandin (6), desertorin B (7), fonsecinone A (8), aurasperone A (9), asperpyrones B and C (10 and 11), aspernigrin B (12), and pyrophen (13), were isolated from a strain of Aspergillus welwitschiae CUGBMF180262. The structures of compounds 1–3 were determined by detailed analysis of HRMS, and 1D/2D NMR experiments, while the absolute configurations of 2 and 3 were determined by comparison of experimental and calculated electronic circular dichroism spectra. 2 and 3 were first reported dimeric hexylitaconic acid derivatives. Compounds 8, 9 and 11 showed moderate antibacterial activities against Helicobacter pylori with minimum inhibitory concentration (MIC) values of 16 μg/mL.
Differences in neural recovery from acute stress between cortisol responders and non-responders
Creators: name: Dimitrov, Annika
name: Demin, Katharine
name: Fehlner, Phöbe
name: Walter, Henrik
name: Erk, Susanne
name: Veer, Ilya M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: stress recovery
subject: fMRI
subject: resting state
subject: functional connectivity
subject: amygdala
subject: cortisol
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Adaptive recovery from a stressor fosters resilience. So far, however, few studies have examined brain functional connectivity in the aftermath of stress, with inconsistent results reported. Focusing on the immediate recovery from psychosocial stress, the current study compared amygdala resting-state functional connectivity (RSFC) before and immediately after psychosocial stress between cortisol responders and non-responders. Differences between groups were expected for amygdala RSFC with regions involved in down-regulation of the physiological stress response, emotion regulation, and memory consolidation. Eighty-six healthy participants (36 males/50 females) underwent a social stress paradigm inside the MRI scanner. Before and immediately after stress, resting-state (RS) fMRI scans were acquired to determine amygdala RSFC. Next, changes in connectivity from pre- to post-stress were compared between cortisol responders and non-responders. Responders demonstrated a cortisol increase, higher negative affect, and decreased heart rate variability (HRV) in response to stress compared to non-responders. A significant Sex-by-Responder-by-Time interaction was found between the bilateral amygdala and posterior cingulate cortex (PCC) and precuneus (p < 0.05, corrected). As males were also more likely to show a cortisol increase to the stress task than females, follow-up analyses were conducted for both sexes separately. Whereas no difference was observed between female responders and non-responders, male non-responders showed an increase in FC after stress between the bilateral amygdala and the PCC and precuneus (p < 0.05, corrected). The increased coupling of the amygdala with the PCC/precuneus, a core component of the default mode network (DMN), might indicate an increased engagement of the amygdala within the DMN directly after stress in non-responders. Although this study was carried out in healthy participants, and the results likely reflect normal variations in the neural response to stress, understanding the mechanisms that underlie these variations could prove beneficial in revealing neural markers that promote resilience to stress-related disorders.
Auschwitz e i limiti della rappresentazione
Creators: name: Härle, Clemens Karl
Publisher: name: Post-filosofie
Year: 2020
Subjects: Auschwitz; rappresentazione; mimesi; affetto puro

description: Partendo da un’osservazione di Jean-Luc Nancy, “La rappresentazione è una presenza presentata, esposta ed esibita”, vengono messe a confronto tre declinazioni della domanda intorno allo statuto della mimesis dopo Auschwitz: quella di Adorno che si può riassumere nella sua frase Scrivere una poe-sia dopo Auschwitz è un atto di barbarie, quella di Jean-Luc Godard che la-menta la mancanza di documenti fotografici e cinematografici dello sterminio degli ebrei d’Europa, quella di Gerhard Richter che in due cicli pittorici, 18. Oktober 1977 e Birkenau, mostra come, in dialogo critico con la fotografia, la pittura contemporanea possa cercare di ‘rappresentare’ eventi politici estremi. A recent observation by Jean-Luc Nancy, “Representation is a presence that is presented, exposed and exhibited”, serves as a starting point to con-front three different ways to conceive the status of mimesis after Auschwitz: Adorno’s affirmation that “to write poetry after Auschwitz is barbarian”; Jean-Luc Godard’s claim that the gas chambers cannot be the only event in the history of the XXth century that lacks photographic and cinematographic documentation; Gerhard Richter’s attempt to demonstrate in two of his major works, 18. Oktober 1977 and Birkenau, how contemporary painting, in critical dialogue with photography, is able to ‘represent’ extreme political events.
description: Post-filosofie, N. 12 (2019): Anno 12. Numero12. Le rivoluzioni dell’alterità
Non-alcoholic fatty liver disease in underweight patients with inflammatory bowel disease: A case-control study
Creators: name: Adams, Lisa C.
name: Lübbe, Falk
name: Bressem, Keno
name: Wagner, Moritz
name: Hamm, Bernd
name: Makowski, Marcus R.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: Non-alcoholic fatty liver disease (NAFLD)
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Non-alcoholic fatty liver disease (NAFLD) was shown to also occur in lean and underweight patients. So far, the prevalence of NAFLD in underweight individuals with and without inflammatory bowel disease (IBD) is insufficiently enlightened. In this cross-sectional age, gender and disease-matched case-control study, underweight patients (BMI<18.5 kg/m(2)) with inflammatory bowel disease (IBD), who underwent abdominal MRI at 1.5 T/3 T with fat-saturated fast-spin-echo imaging from 10/2005-07/2018 were analysed (control-to-caseratio 1:1, n = 130). All patients were additionally investigated for duration, history of surgery, medical treatment, laboratory values, liver and spleen diameters. On MRI, liver fat was quantified by two observers based on the relative signal loss on T2-weighted fast spin-echo MR images with fat saturation compared to images without fat saturation. The prevalence of NAFLD/liver steatosis, defined as a measured intrahepatic fat content of at least 5%, was significantly higher in underweight IBD patients than in normal weight patients (87.6% versus 21.5%, p<0.001). Compared to the cases, the liver fat content of the controls was reduced by -0.19 units on average (-19%; 95%CI: -0.20; -0.14). Similar results were obtained for the subgroup of non-IBD individuals (n = 12; -0.25 units on average (-25%); 95%CI: -0.35; -0.14). Patients with extremely low body weight (BMI <17.5 kg/m(2)) showed the highest liver fat content (+0.15 units on average (+15%) compared to underweight patients with a BMI of 17.5-18.5 kg/m(2) (p<0.05)). Furthermore, underweight patients showed slightly increased liver enzymes and liver diameters. There were no indications of significant differences in disease duration, type of medications or surgery between cases and controls and also, there were no significant differences between observers or field strengths (p>0.05). The prevalence of liver steatosis was higher among underweight IBD and non-IBD patients compared to normal weight controls. Also, underweight patients showed slightly increased liver enzymes and liver diameters, hinting at initial metabolic disturbances.
On the reliability of various enhancement theories for a description of electron-positron densities in metals
Creators: name: Sormann, H.
name: Kontrym-Sznajd, G.
name: West, R. N.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Four theoretical approaches to calculate momentum densities of electron-positron annihilation pairs (MDAP) in crystalline solids are confronted with 3D densities reconstructed from two-dimensional angular correlation (2D-ACAR) data for copper, chromium, and yttrium. It is shown that the Bloch-modified ladder theory, in contrast to other approaches, is able to describe - at least qualitatively - the MDAP profiles for all metals investigated.
Yeast XRS2 and human NBN gene: Experimental evidence for homology using codon optimized cDNA
Creators: name: Demuth, Ilja
name: Krebs, Simon K.
name: Dutrannoy, Véronique
name: Linke, Christian
name: Krobitsch, Sylvia
name: Varon, Raymonda
name: Lang, Christine
name: Raab, Andreas
name: Sperling, Karl
name: Digweed, Martin
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: cross-complementation
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The genes, XRS2 in Saccharomyces cerevisiae and NBN in mammals, have little sequence identity at the amino acid level. Nevertheless, they are both found together with MRE11 and RAD50 in a highly conserved protein complex which functions in the repair of DNA double-strand breaks. Here, we have examined the evolutionary and functional relationship of these two genes by cross-complementation experiments. These experiments necessitated sequence correction for specific codon usage before they could be successfully conducted. We present evidence that despite extreme sequence divergence nibrin can, at least partially, replace Xrs2 in the cellular DNA damage response, and Xrs2 is able to promote nuclear localization of MRE11 in NBS cells. We discuss that the extreme sequence divergence reflects a unique adaptive pressure during evolution related to the specific eukaryotic role for both Xrs2 and nibrin in the subcellular localisation of the DNA repair complex. This, we suggest, is of particular relevance when cells are infected by viruses. The conflict hypothesis of co-evolution of DNA repair genes and DNA viruses may thus explain the very low sequence identity of these two homologous genes.
Psoralen induces liver injuries through endoplasmic reticulum stress signaling in female mice
Creators: name: Yu, Ruili
name: Yu, Yingli
name: Su, Shijia
name: Zhao, Lin
name: Wang, Qin
name: Zhang, Yue
name: Song, Lei
name: Zhou, Kun
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Psoralen is the main coumarin component of Fructus psoraleae. Previously, we have found that psoralen induced hepatocytes apoptosis via PERK and ATF6 related ER stress pathways in vitro. In this study, we investigated the toxicity and ER stress induced by psoralen in female C57 mice. Mice were fed with 80 mg/kg of psoralen intra-gastrically for either 3, 7, or 21 days. Liver and kidney were weighed and their coefficients were calculated. The serum was isolated to examine the biochemical parameters including alanine aminotransferase (ALT) activity, aspartate aminotransferase (AST) activity, alkaline phosphatase (ALP) activity, blood urea nitrogen (BUN), total bile acid (TBA), total bilirubin (TBIL), and creatinine (CRE). The transcription and expression of ER stress-related markers were determined by Wes-automated Protein Simple system, Western blot and RT-PCR. Psoralen administration for 3 days significantly increased liver coefficients but decreased kidney coefficients of mice. Histopathological examination showed minimal inflammatory cell foci and vacuolar degeneration in the liver. Besides, serum levels of ALT, TBA, BUN, and CRE were markedly altered by psoralen. Moreover, psoralen significantly increased expression and transcription levels of ER stress related markers, including Grp78, PERK, eIF2α, ATF4, IRE1α, ATF6, and XBP1. These results illustrated that psoralen induced liver injuries through ER stress signaling in female mice.
MOESM1 of Risk prediction for 30-day mortality among patients with Clostridium difficile infections: a retrospective cohort study
Creators: name: Hsiu-Yin Chiang
name: Huang, Han-Chun
name: Chung, Chih-Wei
name: Yeh, Yi-Chun
name: Yi-Chin Chen
name: Tien, Ni
name: Hsiu-Shan Lin
name: Mao-Wang Ho
name: Chin-Chi Kuo
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1. Supplementary method: Clostridium difficile testing; Figure S1. Time frames for the definition of covarieates; Table S1. Net reclassification of risk prediction score and the published guidelines.
Toxomerus norma
Creators: name: Borges, Zuleica M.
name: Couri, Marcia S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Toxomerus
Toxomerus norma

description: Toxomerus norma (Curran)
(Figs. 33, 119, 120, 121)
 Mesogramma norma Curran, 1930: 10 (descr.); 1934: 399 (key); Hull, 1943b: 13, 29 (key & ill.).
 Mesogramma mulio Hull, 1941c: 311 (descr.); 1943b: 6, 29 (key & ill.).
 Mesograpta norma Fluke, 1956: 227 (cat.).
 Mesograpta mulio Fluke, 1956: 226 (cat.).
 Toxomerus norma Thompson et al., 1976: 53 (cat. & n. comb.).
 Toxomerus mulio Thompson et al., 1976: 52 (cat. & n. comb.); Metz & Thompson, 2001: 228, 238 (key &redescr.), syn. nov.
 Diagnosis. Face 1/2 as long as eye width, yellow; frontal triangle yellow. Proepimeron yellow; scutum black except broadly yellow laterally; scutellum yellow, black pilose; anepimeron brown, yellow dorsomedially. Pro and mesofemora yellow, metafemur yellow with black annulus; pro and meso tibiae yellow, metatibia yellow to brownish. Wing extensively microtrichose; alula broader than cell BM appically, microtrichose. Abdomen with 3 rd and 4 th terga entirely yellow on basal 2/3 which sometimes contain two small medial brown to black spots (Fig. 33). Surstylus broader apicad; postanal process 3/4 as long as surstylus; aedeagus enlarged, proeminent dorsally; superior lobe somewhat quadrangular with short posterodorsal extension, forked distad, with scattered hairs, and setae longer along ventral margin.
 Female genitalia: 9 th tergum somewhat a heart shape black macula; epiproct slender; cercus slender; hypoproct as an rouded arch; 9 th sternum as in Fig. 120; three elliptical spermatecae similar in size (Figs. 119–121).
Length. Body 8.2–10.0 mm, wing 6.3–7.6 mm.
 Discussion. The synonymies were based on the examination of the male holotypes of Mesogramma mulio and Mesogramma norma.
 Type material examined. Holotype. PANAMA. Corozal: Mesogramma norma, male, 16/I/1929, C. H. Curran (AMNH).
 Other material examined. MEXICO. Cordoba: ♂, 17/XII/1967, Fredk Knab (USNM); ECUADOR. Napo: Santa Cecília, ♀, 17/V/1967, Ashley B. Gurney (USNM); VENEZUELA. Aragua: Ocumare de La Costa, ♀, 10–11/VI/1976, A. S. Menke & D. Vincent (USNM); 2 ♂, 12/VI/1976, A. S. Menke & D. Vincent (USNM); Zulia: Puerto de Cata 2 ♂, 10–11/VI/1976, A. S. Menke & D. Vincent (USNM); PARAGUAY. Villarrica: ♂, IX/1938, F. Shade (USNM); BRAZIL. Pará: Belém, ♀, 1/VI/1967, Y. Sedman (USNM); Araguaia, ♂, VII/1959, M. Alvarenga (DZUP). Pernambuco: Caruaru, ♀, VII/1974 (MZSP). São Paulo: Barueri, ♂, 23/III/1957, K. Lenko (USNM). Paraná: Curitiba, ♀, IV/1976, H. S. Telford (DZUP).
 Geographical record. Widespread, from Mexico to southern South America.
description: Published as part of Borges, Zuleica M. & Couri, Marcia S., 2009, Revision of Toxomerus Macquart, 1855 (Diptera: Syrphidae) from Brazil with synonymic notes, identification key to the species and description of three new species 2179, pp. 1-72 in Zootaxa 2179 on page 43
Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers
Creators: name: Heim, Daniel
name: Montavon, Grégoire
name: Hufnagl, Peter
name: Müller, Klaus-Robert
name: Klauschen, Frederick
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: Cancer
subject: Genomics
subject: Pan-cancer analysis
subject: Proteomics
subject: Targeted cancer therapy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Comprehensive mutational profiling data now available on all major cancers have led to proposals of novel molecular tumor classifications that modify or replace the established organ- and tissue-based tumor typing. The rationale behind such molecular reclassifications is that genetic alterations underlying cancer pathology predict response to therapy and may therefore offer a more precise view on cancer than histology. The use of individual actionable mutations to select cancers for treatment across histotypes is already being tested in the so-called basket trials with variable success rates. Here, we present a computational approach that facilitates the systematic analysis of the histological context dependency of mutational effects by integrating genomic and proteomic tumor profiles across cancers. Methods: To determine effects of oncogenic mutations onprotein profiles, we usedtheenergy distance, which comparesthe Euclidean distancesof protein profiles in tumors with an oncogenic mutation (inner distance) to that in tumors without the mutation (outer distance) and performed Monte Carlo simulations for the significance analysis. Finally, the proteins were ranked by their contribution to profile differences to identify proteins characteristic of oncogenic mutation effects across cancers. Results: We apply our approach to four current proposals of molecular tumor classifications and major therapeutically relevant actionable genes. All 12 actionable genes evaluated show effects on the protein level in the corresponding tumor type and showed additional mutation-related protein profiles in 21 tumor types. Moreover, our analysis identifies consistent cross-cancer effects for 4 genes (FGFR1, ERRB2, IDH1, KRAS/NRAS) in 14 tumor types. We further use cell line drug response data to validate our findings. Conclusions: This computational approach can be used to identify mutational signatures that have protein-level effects and can therefore contribute to preclinical in silico tests of the efficacy of molecular classifications as well as the druggability of individual mutations. It thus supports the identification of novel targeted therapies effective across cancers and guides efficient basket trial designs.
Taisei yochi zusetsu. Kan no 9-10
泰西輿地圖説.巻之九-十
Creators: name: (:Null)
Publisher: name: Edo : Matsumoto Zenbē
Year: 2021

description: Vol. 1-3 contains a preface by 鳩谷孔平 Hatotani Kōhei and an index. There are 27 maps in vol. 15-17, based on European models; most maps are double-page. Contents: Vol. 1-3. General introduction to Europe, Portugal, Spain -- Vol. 4-5. France, England -- Vol. 6-8. Netherlands, Switzerland, Italy -- Vol. 9-10. Germany, Scandinavia -- Vol. 11-14. Poland, Moscovia (Russia), Hungary, Greece -- Vol. 15-17 maps of Europe, Arctic regions, plans of cities. Cited in: WSN; 110-111
MOESM4 of The effect of pneumococcal immunization on total and antigen-specific B cells in patients with severe chronic kidney disease
Creators: name: Gaultier, Gabrielle
name: McCready, William
name: Ulanova, Marina
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 60506 Virology

description: Additional file 4: Table S4. Concentrations and fold change of pneumococcal 6B and 14 IgG antibodies pre- and 28 days post-immunization. Geometric mean concentration (GMC) with 95% confidence intervals (CI) in severe chronic kidney disease patients who are pneumococcal vaccine naïve (n = 22) or previously immunized with PPV23 > 1 year ago (n = 34) pre- and 28 days post-immunization with PCV13. The fold change represents the response to PCV13 immunization. * compares day 0 pre-immunization and day 28 post-immunization antibody concentrations for each serotype and patient group, + compares the pre-immunization concentrations between patient groups, # compares the fold change for each serotype between groups. Statistical significance determined by Mann- Whitney U test, * p
Gravitational stress during parabolic flights reduces the number of circulating innate and adaptive leukocyte subsets in human blood
Creators: name: Stervbo, Ulrik
name: Roch, Toralf
name: Kornprobst, Tina
name: Sawitzki, Birgit
name: Grütz, Gerald
name: Wilhelm, Andreas
name: Lacombe, Francis
name: Allou, Kaoutar
name: Kaymer, Markus
name: Pacheco, Antoine
name: Vigne, Jacques
name: Westhoff, Timm H.
name: Seibert, Felix S.
name: Babel, Nina
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2018
Subjects: subject: leukocyte
subject: space flight
subject: extreme sport
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Gravitational stress occurs during space flights or certain physical activities including extreme sports, where the change in experienced gravitational acceleration can reach large magnitudes. These changes include reduction and increase in the physical forces experienced by the body and may potentially induce pathogenic alterations of physiological processes. The immune system is known to regulate most functions in the human organism and previous studies suggest an impairment of the immune function under gravitational stress. However, systematic studies aiming to investigate the effect of gravitational stress on cellular immune response in humans are lacking. Since parabolic flights are considered as feasible model to investigate a short-term impact of gravitational changes, we evaluated the influence of gravitational stress on the immune system by analyzing leukocyte numbers before and after parabolic flight maneuvers in human blood. To correct for circadian effects, samples were taken at the corresponding time points on ground the day before the flight. The parabolic flight maneuvers led to changes in numbers of different leukocyte subsets. Naïve and memory T and B cell subsets decreased under gravitational stress and lower numbers of basophils and eosinophils were observed. Only circulating neutrophils increased during the parabolic flight. The observed changes could not be attributed to stress-induced cortisol effects, since cortisol levels were not affected. Our data demonstrate that the gravitational stress by parabolic flights can affect all parts of the human immune system. Consequently, it is possible that gravitational stress can have clinically relevant impacts on the control of immune responses.
Five-dimensional Black Hole and Particle Solution with Non-Abelian Gauge Field
Creators: name: Okuyama, Naoya
name: Maeda, Kei-ichi
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study the 5-dimensional Einstein-Yang-Mills system with a cosmological constant. Assuming a spherically symmetric spacetime, we find a new analytic black hole solution, which approaches asymptotically "quasi-Minkowski", "quasi anti-de Sitter", or "quasi de Sitter" spacetime depending on the sign of a cosmological constant. Since there is no singularity except for the origin which is covered by an event horizon, we regard it as a localized object. This solution corresponds to a magnetically charged black hole. We also present a singularity-free particle-like solution and a non-trivial black hole solution numerically. Those solutions correspond to the Bartnik-McKinnon solution and a colored black hole with a cosmological constant in the 4-dimensions. We analyze their asymptotic behaviors, spacetime structures and thermodynamical properties. We show that there is a set of stable solutions if a cosmological constant is negative.
description: 17 pages, 17 figures, submitted to PRD