cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Gestation and early-life environment and its impact on welfare and cognition in pigs
Creators: name: Author, Unknown
Publisher: name: University of Lincoln
Year: 2023

description: Assessing cognitive capabilities of animals is key to understanding their welfare needs.This is especially the case during major life events or following a change in conditions,when cognition and welfare needs may change or fluctuate. One such major life event isgestation, when a female’s physical and physiological environment can changesignificantly. In livestock, pregnant females are also frequently subjected to anenvironmental change, as they are typically separated from other conspecifics. The aim ofthis thesis was to investigate the impact that gestation and early life environment may havein pigs. This thesis includes two main studies, the first of which focuses on the impact ofpregnancy on cognition and mood, investigating memory, problem solving and personalitythroughout pregnancy. This is also the first study, to my knowledge, to use a cognitivebias approach to assess changes in mood during pregnancy in a non-human animal. Indoing this it was found that there is a significant shift in the pigs’ mood state betweenpre/early and mid/late gestational stages, suggesting that they became increasinglypessimistic as they progressed through pregnancy. The second study investigates how twokey early life factors, the size and sex ratio of the litter an individual is born into, mayinfluence its later body and tail injury scores as well as cognitive bias when the pigs areplaced in mixed groups in either a barren or enriched environment. A key finding from thisstudy is that the sex ratio of the litter an individual originates from can have an effect onits body scores after leaving its litter-mates. It was also found that litter size and relativeweight of the individual within the group can impact upon tail injury scores, though thenature of the effect also depends on the pigs’ housing environment. Results correlate withprevious findings that litter size is associated with litter sex ratio. Overall this thesisprovides an initial insight into the impacts of pregnancy on a mother’s cognitive bias andsuggests that environmental factors in utero and in early life can influence welfare in laterlife.
title: La construction d'une excursion créative : éléments de problématisation
title: La construction d'une excursion créative : éléments de problématisation
titleType: AlternativeTitle
Creators: name: Figueiredo, David
name: Mérinat, Vivian
Publisher: name: Unknown
Year: 0
Subjects: subject: excursion pédagogique
subject: école du dehors
subject: pédagogie de projet
subject: pédagogie de l’expérience
subject: excursion créative
subject: créativité
subject: TIC
subject: paysage

description: Ce travail de recherche prend comme objet d’étude un dispositif marginal de l’enseignement : la création et l’organisation d’excursions. On en dénombre trois types, parmi lesquels on retrouve l’excursion-observation qui consiste en l’organisation d’une sortie pendant laquelle l’enseignant montre tandis que l’élève observe et mémorise ; l’excursion « voir et ressentir » pendant laquelle les élèves sont amenés à découvrir de nouveaux lieux et mettre leurs sens en jeu (écouter la forêt les yeux bandés, etc.) et un troisième type, l’excursion créative qui conduit les élèves à voir, ressentir et transformer. C’est ce type d’excursion, marginale à son tour car en voie d’élaboration, que nous avons voulu présenter et expérimenter ici. Cette étude s’insère ainsi dans le contexte de nouvelles approches pédagogiques et propose des idées alternatives pour essayer de donner du sens à ce qui est proposé aux élèves pendant leur scolarité. Ainsi, l’idée principale de cette recherche est de proposer une réflexion sur les possibilités qu’a un enseignant de transformer une sortie scolaire en une excursion créative, riche en expériences humaines et cognitives, et qui offre l’occasion pour les élèves –et lui-même– de vivre une expérience marquante du point de vue des sens, des émotions et du rapport à l’environnement et au travers de laquelle chacun est amené à endosser une posture active, collaborative et créatrice. Afin de mesurer la faisabilité et l’efficacité de la réalisation d’une excursion créative, nous nous sommes appuyés sur une excursion créée en Lavaux dans le cadre d’un projet élaboré au sein de la HEP Vaud. Sur la base de notre travail de création, de réalisation et d’observation de cette excursion, nous avons défini une série d’hypothèses qui nous permettent de guider nos recherches ; par le biais de la conceptualisation d’éléments théoriques nous tentons de définir les éléments essentiels, et par là-même contingents, à la réalisation d’une excursion créative par un enseignant. Ce type d’approche représente un défi pour les enseignants puisqu’elle implique de leur part un investissement personnel, tant sur le plan émotionnel que temporel. Par ailleurs, l’excursion créative est encore peu étudiée et des approfondissements méritent d’être apportés. Nous espérons que ce travail y participe.
The soil reference shrinkage curve
Creators: name: Chertkov, V. Y.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Geophysics (physics.geo-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: A recently proposed model showed how a clay shrinkage curve is transformed to the soil shrinkage curve at the soil clay content higher than a critical one. The objective of the present work was to generalize this model to the soil clay content lower a critical one. I investigated (i) the reference shrinkage curve, that is, one without cracks; (ii) the superficial layer of aggregates, with changed pore structure compared with the intraaggregate matrix; and (iii) soils with sufficiently low clay content where there are large pores inside the intraaggregate clay (so-called lacunar pores). The methodology is based on detail accounting for different contributions to the soil volume and water content during shrinkage. The key point is the calculation of the lacunar pore volume variance at shrinkage. The reference shrinkage curve is determined by eight physical soil parameters: (1) oven-dried specific volume; (2) maximum swelling water content; (3) mean solid density; (4) soil clay content; (5) oven-dried structural porosity; (6) the ratio of aggregate solid mass to solid mass of intraaggregate matrix; (7) the lacunar factor that characterizes the rate of the lacunar pore volume change with water content; and (8) oven-dried lacunar pore volume. The model was validated using available data. The model predicted value of the slope of the reference shrinkage curve in the basic shrinkage area is equal to unity minus the lacunar factor value, and is between unity and zero in the agreement with observations.
description: 31 pages, 11 figures, 3 tables
Dusty shells surrounding the carbon variables S Scuti and RT Capricorni
Creators: name: Mecina, M.
name: Kerschbaum, F.
name: Groenewegen, M. A. T.
name: Ottensamer, R.
name: Blommaert, J. A. D. L.
name: Mayer, A.
name: Decin, L.
name: Luntzer, A.
name: Vandenbussche, B.
name: Posch, Th.
name: Waelkens, C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: For the Mass-loss of Evolved StarS (MESS) programme, the unprecedented spatial resolution of the PACS photometer on board the Herschel space observatory was employed to map the dusty environments of asymptotic giant branch (AGB) and red supergiant (RSG) stars. Among the morphologically heterogeneous sample, a small fraction of targets is enclosed by spherically symmetric detached envelopes. Based on observations in the 70 μm and 160 μm wavelength bands, we investigated the surroundings of the two carbon semiregular variables S Sct and RT Cap, which both show evidence for a history of highly variable mass-loss. S Sct exhibits a bright, spherically symmetric detached shell, 138" in diameter and co-spatial with an already known CO structure. Moreover, weak emission is detected at the outskirts, where the morphology seems indicative of a mild shaping by interaction of the wind with the interstellar medium, which is also supported by the stellar space motion. Two shells are found around RT Cap that were not known so far in either dust emission or from molecular line observations. The inner shell with a diameter of 188" shows an almost immaculate spherical symmetry, while the outer ~5' structure is more irregularly shaped. MoD, a modification of the DUSTY radiative transfer code, was used to model the detached shells. Dust temperatures, shell dust masses, and mass-loss rates are derived for both targets.
Bloch oscillations in atom interferometry
Creators: name: Cladé, Pierre
Publisher: name: arXiv
Year: 2014
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In Paris, we are using an atom interferometer to precisely measure the recoil velocity of an atom that absorbs a photon. In order to reach a high sensitivity, many recoils are transferred to atoms using the Bloch oscillations technique. In this lecture, I will present in details this technique and its application to high precision measurement. I will especially describe in details how this method allows us to perform an atom recoil measurement at the level of $1.3 \times 10^{-9}$. This measurement is used in the most precise determination of the fine structure constant that is independent of quantum electrodynamics.
Assessing User Experience in A Virtual Reality Crowd Simulation
Creators: name: Greenwood, Jacob
Publisher: name: University of Lincoln
Year: 2023

description: Agent-based crowd simulations are used for modelling building and space usage,allowing designers to explore hypothetical real-world scenarios, including extraordinaryevents such as evacuations. Existing work which engages Virtual Reality (VR) as a platformfor crowd simulations has been primarily focussed on the validation of simulation modelsthrough observation; that is the use of embellishments to enhance a sense of immersion orconstrained studies of proxemics. However, human participation in crowd simulations alsohas the potential to provide richer and more informative simulation outcomes. This issuehas not yet been widely considered by researchers and warrants further study of userexperience and behaviour.This work examines VR crowd simulation through the lens of user experience andsimulation outcomes. A task-based simulation scenario has been created in which aparticipant walks freely, and interacts with agents using the same social-force model whichmediates agent-to-agent interactions. It examines and reports the effects of crowd densityon both the users affective state and behaviour, also comparing it with that of simulatedagents. The results gained from this study indicate a significant increase in negative affectwith density, measured using a self-report scale, it also shows significant differences insome aspects of user behaviour, such as increased instinctive reactions during high-densitysituations. This work then discusses how the results relate to VR simulation design for mixedhuman-agent scenarios.
String-Averaging Expectation-Maximization for Maximum Likelihood Estimation in Emission Tomography
Creators: name: Helou, E. S.
name: Censor, Y.
name: Chen, T. -B.
name: Chern, I-L.
name: De Pierro, Á. R.
name: Jiang, M.
name: Lu, H. H. -S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Medical Physics (physics.med-ph)
subject: Computers and Society (cs.CY)
subject: Numerical Analysis (math.NA)
subject: Optimization and Control (math.OC)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: We study the maximum likelihood model in emission tomography and propose a new family of algorithms for its solution, called String-Averaging Expectation-Maximization (SAEM). In the String-Averaging algorithmic regime, the index set of all underlying equations is split into subsets, called "strings," and the algorithm separately proceeds along each string, possibly in parallel. Then, the end-points of all strings are averaged to form the next iterate. SAEM algorithms with several strings presents better practical merits than the classical Row-Action Maximum-Likelihood Algorithm (RAMLA). We present numerical experiments showing the effectiveness of the algorithmic scheme in realistic situations. Performance is evaluated from the computational cost and reconstruction quality viewpoints. A complete convergence theory is also provided.
Non-universal gaugino masses and semi-natural supersymmetry in view of the Higgs boson discovery
Creators: name: Martin, Stephen P.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I consider models with non-universal gaugino masses at the gauge coupling unification scale, taking into account the Higgs boson discovery. Viable regions of parameter space are mapped and studied in the case of non-universality following from an F-term in a linear combination of singlet and adjoint representations of SU(5). I consider, in particular, "semi-natural" models that have small μ, with gaugino masses dominating the supersymmetry breaking terms at high energies. Higgsino-like particles are then much lighter than all other superpartners, and the prospects for discovery at the Large Hadron Collider can be extremely challenging.
description: 22 pages. v2: references added
An empirical Bayes testing procedure for detecting variants in analysis of next generation sequencing data
Creators: name: Zhao, Zhigen
name: Wang, Wei
name: Wei, Zhi
Publisher: name: arXiv
Year: 2014
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: Because of the decreasing cost and high digital resolution, next-generation sequencing (NGS) is expected to replace the traditional hybridization-based microarray technology. For genetics study, the first-step analysis of NGS data is often to identify genomic variants among sequenced samples. Several statistical models and tests have been developed for variant calling in NGS study. The existing approaches, however, are based on either conventional Bayesian or frequentist methods, which are unable to address the multiplicity and testing efficiency issues simultaneously. In this paper, we derive an optimal empirical Bayes testing procedure to detect variants for NGS study. We utilize the empirical Bayes technique to exploit the across-site information among many testing sites in NGS data. We prove that our testing procedure is valid and optimal in the sense of rejecting the maximum number of nonnulls while the Bayesian false discovery rate is controlled at a given nominal level. We show by both simulation studies and real data analysis that our testing efficiency can be greatly enhanced over the existing frequentist approaches that fail to pool and utilize information across the multiple testing sites.
description: Published in at http://dx.doi.org/10.1214/13-AOAS660 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)
title: Enseigner l'écriture créative en Secondaire II
title: Enseigner l'écriture créative en Secondaire II
titleType: AlternativeTitle
Creators: name: Magnenat, Nadejda
Publisher: name: Unknown
Year: 0
Subjects: subject: écriture créative
subject: atelier d’écriture
subject: écrits intermédiaires
subject: sujet écrivant
subject: liberté esthétique
subject: norme scolaire

description: Faire écrire des « textes de création » aux élèves du secondaire II fait partie des plans d'étude de la DGEP. Ce type d’exercices contribue à renforcer la créativité des élèves et les aide à se construire en tant que sujets pensants. Mais peut-on véritablement enseigner l’écriture créative en milieu scolaire ? Pour quelles finalités ? Le dispositif des ateliers d’écriture, qui s’est notamment développé dans la mouvance du Creative Writing anglo-saxon (un concept qui considère que le métier d’écrivain s’apprend et qui voit fleurir depuis les années 2010 en France des cursus universitaires en création littéraire) permet d’expérimenter ce type d’activité avec les élèves. Ces séances d’écriture en atelier se démarquent des autres tâches d’écriture au sein de l’enseignement du français par le fait que la créativité s’accommode mal des normes du français prescriptif, puisque « dans un texte littéraire, la "faute", l’"erreur" peuvent faire sens » (Bach, 2014). Mais pour autant, ce type d’exercice apparaît profitable à l’élève comme à l’enseignant·e. L’écriture devient un apprentissage fondamental, dès lors que « l’élève, l’étudiant, écrit pour dire, penser, commenter, imaginer quelque chose, et ce « dit » participe à part entière à son développement et à celui de son langage. » (Bucheton, 2014). Quant à l’enseignant·e, les écrits ainsi créés sont des outils d’enseignement qui lui permettent d’accéder à l’état des savoirs de ses élèves. Après avoir cerné brièvement en théorie les bénéfices et les limites de tels exercices, je rendrai compte d’une démarche effectuée par le biais de « cahiers d’écriture », élaborée lors d’un semestre, dans des classes du post obligatoire de deux filières différentes, l’une en 2e année de l’Ecole de maturité et l’autre en 1re année de l’Ecole de culture générale. Le bilan de cet exercice voudrait mettre en évidence et clarifier les différents enjeux qui sont à l’oeuvre dans ce « faire écrire » créatif.
Atomic site sensitive processes in low energy ion-dimer collisions
Creators: name: Iskandar, W.
name: Matsumoto, J.
name: Leredde, A.
name: Fléchard, X.
name: Gervais, B.
name: Guillous, S.
name: Hennecart, D.
name: Méry, A.
name: Rangama, J.
name: Zhou, C. L.
name: Shiromaru, H.
name: Cassimi, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Electron capture processes for low energy Ar9+ ions colliding on Ar2 dimer targets are investigated, focusing attention on charge sharing as a function of molecule orientation and impact parameter. A preference in charge-asymmetric dissociation channels is observed, with a strong correlation between the projectile scattering angle and the molecular ion orientation. The measurements provide here clear evidences that projectiles distinguish each atom in the target and, that electron capture from near-site atom is favored. Monte Carlo calculations based on the classical over-the-barrier model, with dimer targets represented as two independent atoms, are compared to the data. They give a new insight into the dynamics of the collision by providing, for the di erent electron capture channels, the two-dimensional probability maps p(~b), where ~b is the impact parameter vector in the molecular frame.
Macroevolutionary Diversification of Multivariate Body Plan in a Prominent Lizard Adaptive Radiation
Creators: name: Author, Unknown
Publisher: name: University of Lincoln
Year: 2023

description: Natural selection theory predicts that similar ecological pressures can result in similarphenotypes evolving in distantly related species through a process known as convergentevolution. Although there are many described cases of species adaptively evolving similarphenotypes in response to the same habitats (i.e., “ecomorphs”), this is not a universaloutcome of natural selection. Liolaemus lizards embody an exceptional example ofadaptive radiation where, thus far, studies have not identified any evidence ofecomorphological evolution. Why some lineages display such signals of convergentevolution while others do not remains an open question. Here, shape was more accuratelyquantified by using geometric morphometrics (as opposed to the linear measures ofmorphology used previously) to address the question of whether Liolaemus lizards haveundergone convergent evolution in body morphology and to conduct phylogeneticmodelling to quantify patterns and rates of multivariate morphological evolution in thisradiation. Further to this, the effect of diet and parity mode on morphology were explored.The morphometric analysis produced three principal component (PC) axes that explainedover 10% of variance. Each axis captures different changes in shape; PC1 shows areduction in relative head size when the body becomes wider and more elongated andvice versa. PC2 shows changes in the width of the body, with little change in the lengthof the body and of changes in the head. PC3 shows lengthening in the posterior of thebody while there is a pinching towards the front of the body and an increase in relativehead size and vice versa. Results generally showed no significant separation in bodyshape between microhabitat groups, and thus suggest ecomorphs are not present. Diet andparity groups were significantly separated, however, not when phylogeny was includedin the analyses. Phylogenetic macroevolutionary analyses were used to develop anunderstanding of the evolution of biodiversity. OU models of evolution were found to bethe best fitting evolutionary models in explanation of the evolution of shape withinLiolaemus when BM, OU, ? and ? models were fit. Phenotypic rate variation showedsome increases in rate of evolution on PC1 whereas PC2 and PC3 showed decreases.PGLS showed a significant relationship between SVL and PC1 and for SVL and PC2when microhabitat, parity and diet were included. Pairwise comparisons showed asignificant difference between insectivorous and herbivorous species for SVL and PC1open-ground shrubs and open ground species for SVL and PC2. The best fitting model 9for PC1 and PC2 included microhabitat and diet, but not parity, for PC3 the best fittingmodel included diet and parity, but not microhabitat. Results suggest the lack of anecomorphological relationship could be a consequence of other ecological factorsexerting a stronger pressure on the evolution of morphology or that the adaptations arepresent but methodologies are not appropriate to identify them.
Phasia barbifrons species­group
Creators: name: Sun, Xuekui
name: Marshall, Stephen A.
Publisher: name: Zenodo
Year: 2003
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tachinidae
Phasia
Phasia barbifrons
Phasia barbifrons species­Group

description: 3.3. The Phasia barbifrons species­group
 The Phasia barbifrons species­group includes all the species previously placed in the subgenera Stackelbergella Draber­Mońko (Draber­Mońko 1965) and Barbella Draber­Mońko (Draber­Mońko 1965).
 Diagnosis: Eyes separated by a distance equal to or larger than ocellus (male); frontoorbital plate haired laterally, strongly swollen; dorsal facets of eye larger than ventral ones; inner margins of eye divergent; gena and occiput hairs black. Length of oral opening always less than 2.5 times width. Thorax black, shining or thinly pruinose. Scutellum black, with two pairs of marginal setae. Basicosta brown to black. Abdomen black, subovate. Male surstylus longer than cercus, straight; epiphallus and distiphallus partly sclerotized; postgonite well developed, apex pointed.
description: Published as part of Sun, Xuekui & Marshall, Stephen A., 2003, Systematics of Phasia Latreille (Diptera: Tachinidae), pp. 1-320 in Zootaxa 276 (1) on page 47, DOI: 10.11646/zootaxa.276.1.1, http://zenodo.org/record/5019510
Exact quasi-normal modes for the near horizon Kerr metric
Creators: name: Cvetic, M.
name: Gibbons, G. W.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the quasi-normal modes of a massless scalar field in a general sub-extreme Kerr back- ground by exploiting the hidden SL(2, R) x SL(2, R) x SO(3) symmetry of the subtracted geometry approximation. This faithfully models the near horizon geometry but locates the black hole in a confining asymptotically conical box analogous to the anti-de-Sitter backgrounds used in string the- ory. There are just two series of modes, given in terms of hypergeometric functions and spherical harmonics, reminiscent of the left-moving and right-moving degrees in string theory: one is over- damped, the other is underdamped and exhibits rotational splitting. The remarkably simple exact formulae for the complex frequencies would in principle allow the determination of the mass and angular momentum from observations of a black hole. No black hole bomb is possible because the Killing field which co-rotates with the horizon is everywhere timelike outside the black hole.
description: 4 pages
A Fabrication Route for Arrays of Ultra-low-Noise MoAu Transition Edge Sensors on Thin Silicon Nitride for Space Applications
Creators: name: Glowacka, D. M.
name: Crane, M.
name: Goldie, D. J.
name: Withington, S.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We describe a process route to fabricate arrays of Ultra-low-Noise MoAu Transition Edge Sensors (TESs). The low thermal conductance required for space applications is achieved using 200 nm-thick Silicon Nitride (SiNx ) patterned to form long-thin legs with widths of 2.1 μm. Using bilayers formed on SiNx islands from films with 40 nm-thick Mo and Au thicknesses in the range 30 to 280 nm deposited by dc-sputtering in ultra-high vacuum we can obtain tunable transition temperatures in the range 700 to 70 mK. The sensors use large-area absorbers fabricated from high resistivity, thin-film beta-phase Ta to provide impedance-matching to incident radiation. The absorbers are patterned to reduce the heat capacity associated with the nitride support structure and include Au thermalizing features to assist the heat flow into the TES. Arrays of 400 detectors at the pixel spacing required for the long-wavelength band of the far-infrared instrument SAFARI are now being fabricated. Device yields approaching 99% are achieved.
description: 6 pages 4 figures
Identification of volatile organic chemicals in diseased and damaged vegetables.
Creators: name: Fothergill, James
Publisher: name: University of Lincoln
Year: 2023

description: The main objective of this project was to see if volatile organic compounds could be identified in unprocessed vegetables. Once the identification of possible marker compounds was completed, a variety of vegetables with either disease, damage or physiological changes associated with aging were analysed. Potatoes, onions and broccoli were analysed, these vegetables were chosen by some of the project’s co-funders as being economically important The sample of vegetable was placed in an airtight container and the sample was allowed to equilibrate at room temperature for 45 minutes, then a solid phase microextraction fibre (SPME) was inserted through the valve and the fibre exposed for 50 minutes. The fibre was then retracted into its holder prior to analysis using a Gas Chromatograph/Mass Spectrometer (GC/MS). The sample was then analysed using the GC/MS and the peaks identified using the built-in library in the instrument software. In the case of potatoes, no changes in volatiles were observed during the sprouting process or in the case of physical damage. However, changes were identified in the case of potatoes with a variety of diseases, these changes in volatiles were the same regardless of the disease present. The compounds found for potatoes were trimethylamine, 2-butanone, 2,3-butanedione, 3-hydroxy-2-butanone and 2,3-butanediol. The analysis of onions showed differences in the volatiles between uninfected/control samples and those with thick neck, basal rot, internal rot and neck rot. The compounds found were 1-propanethiol, methyl propyl sulphide, methyl propyl disulphide and dipropyl sulphide However, the change in volatiles could not be used to differentiate between the different rots. For broccoli differences were found between control and samples with wet rot. The compounds found included dimethyl sulphide, dimethyl disulphide, dimethyl trisulphide and 1-undecene. The differences were then used to investigate these changes in volatiles in relation to use by dates of pre-packaged broccoli, this investigation showed none of the marker compounds at significant levels for those samples analysed before or on their use by date.
Uniform estimates for the semi-periodic eigenvalues of the singular differential operators
Creators: name: Mikhailets, Vladimir
name: Molyboga, Volodymyr
Publisher: name: arXiv
Year: 2014
Subjects: subject: Functional Analysis (math.FA)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics
subject: 34B05 47A10 34L15

description: Let $m\in \mathbb{N}$, $α\in[0,1]$, and $V$ be a 1-periodic complex-valued distribution in the negative Sobolev space $H^{-mα}[0,1]$. The singular non-self-adjoint eigenvalue problem $D^{2m}u+V u=λu$, $D=-i d/dx$, with semi-periodic boundary conditions is investigated. The uniform in $V$ asymptotic and non-asymptotic eigenvalue estimates are found and proved. The case of periodic boundary conditions was studied by authors earlier.
description: 23 pages
The Role of JAK2 in Myeloproliferative Neoplasms
Creators: name: Lally, James
Publisher: name: University of Lincoln
Year: 2023

description: Myeloproliferative Neoplasms (MPNs) are a group of clonally derived stem-cell disorders ofhaematopoietic progenitors resulting in a proliferation of differentiated myeloid cell types. Theyinclude polycythaemia vera (PV), essential thrombocythaemia (ET), and myelofibrosis (MF). JAK2encodes a non-receptor tyrosine kinase and mutations in this gene are found in a large percentage ofMPN cases. It is present in approximately 95% of PV and between 50-60% of ET and PMF cases. JAK2plays a key role in cell proliferation and differentiation of haematopoietic stem cells to mature bloodcells.Expression of key haematopoietic genes were studied along with their relationship to haematologicalparameters and JAK2 mutational status. Anagrelide was used to target the haematopoietictranscription factor, GATA1, in MPN model cell lines. The effect of this drug on downstream effectorsof megakaryocytic differentiation was also studied to determine potential mechanisms for its antiplatelet activity in essential thrombocythaemia. Ruxolitinib, a JAK1/2 inhibitor, was used to block JAK2and the downstream effects on STAT, SOCS and interferon-gamma target proteins were quantified.Global proteomic changes were studied, using isobaric tagging and relative quantification and LCMS/MS. This inhibitor was also used to examine the importance of JAK2 signalling in erythropoiesisand colony growth in primitive progenitor cells isolated from MPN patients.GATA1 expression was found to be dysregulated in the PBMCs of ET patients. In cell lines, expressionof downstream GATA1 targets were found to be downregulated during inhibition of megakaryopoiesisusing anagrelide. Functional protein analysis showed that STAT1 and associated key molecularpathways involved in interferon signalling were the target of JAK2 inhibition by ruxolitinib.The results in this study suggest a potential role for GATA1 as a disease biomarker, independent ofJAK2 mutational status. The activity of the anti-platelet drug, anagrelide, may in part be due totargeting of GATA1 downstream targets. STAT1 is likely to play a key role in MPN pathogenesis andresponse to JAK inhibitor therapies.
Sparkling EUV bright dots observed with Hi-C
Creators: name: Regnier, S.
name: Alexander, C. E.
name: Walsh, R. W.
name: Winebarger, A. R.
name: Cirtain, J.
name: Golub, L.
name: Korreck, K. E.
name: Mitchell, N.
name: Platt, S.
name: Weber, M.
name: De Pontieu, B.
name: Title, A.
name: Kobayashi, K.
name: Kuzin, S.
name: DeForest, C. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Observing the Sun at high time and spatial scales is a step towards understanding the finest and fundamental scales of heating events in the solar corona. The Hi-C instrument has provided the highest spatial and temporal resolution images of the solar corona in the EUV wavelength range to date. Hi-C observed an active region on 11 July 2012, which exhibits several interesting features in the EUV line at 193Å: one of them is the existence of short, small brightenings ``sparkling" at the edge of the active region; we call these EUV Bright Dots (EBDs). Individual EBDs have a characteristic duration of 25s with a characteristic length of 680 km. These brightenings are not fully resolved by the SDO/AIA instrument at the same wavelength, however, they can be identified with respect to the Hi-C location of the EBDs. In addition, EBDs are seen in other chromospheric/coronal channels of SDO/AIA suggesting a temperature between 0.5 and 1.5 MK. Based on their frequency in the Hi-C time series, we define four different categories of EBDs: single peak, double peak, long duration, and bursty EBDs. Based on a potential field extrapolation from an SDO/HMI magnetogram, the EBDs appear at the footpoints of large-scale trans-equatorial coronal loops. The Hi-C observations provide the first evidence of small-scale EUV heating events at the base of these coronal loops, which have a free magnetic energy of the order of 10$^{26}$ erg.
description: 10 pages, 13 figures (figure 1 at low resolution), in press
Formation of different isotopomers of chloronium in the interstellar medium
Creators: name: Majumdar, Liton
name: Das, Ankan
name: Chakrabarti, Sandip K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Main focus of this paper is to explore the possibility of findings two deuterated isotopomers of H2Cl+ (Chloronium) in and around the Interstellar Medium (ISM). Presence of Chloronium ion has recently been confirmed by Herschel Space Observatory's Heterodyne Instrument for the Far-Infrared (Neufeld et al., 2012). It observed para-chloronium towards six sources in the Galaxy. Existence of its deuterated isotopomers (HDCl+ & D2Cl+) are till date not discussed in the literature. We find that these deuterated gas phase ions could be destroyed by various ion-molecular reactions, dissociative recombination (DR) and by cosmic rays (CR). We compute all the Ion-molecular (polar) reaction rates by using the parameterized trajectory theory and the Ion-molecular (non-polar) reaction rates by using the Langevin theory. For DR and CR induced reactions, we adopt two well behaved rate formulas. We also include these rate coefficients into our large gas-grain chemical network to study the chemical evolution of these species around the outer edge of the cold dense cloud. In order to study spectral properties of chloronium ion and its two deuterated isotopomers, we have carried out quantum chemical simulations. We calculated ground state properties of these species by employing second order Moller-Plesset perturbation theory (MP2) along with quadruple-zeta correlation consistent (aug-cc-pVQZ) basis set. Infrared and electronic absorption spectra of these species are calculated by using the same level of theory. MP2/aug-cc-pVQZ level of theory is used to report the different spectroscopic constants of these gas phase species. These spectroscopic constants are essential to predict rotational transitions of these species. Our predicted column densities of D2Cl^+, HDCl^+ along with the spectral information may enable their future identification around outer edges of cold dark clouds.
description: 14 pages, 7 figures, accepted for publication in ApJ
JIMWLK evolution for multi-particle production with rapidity correlations
Creators: name: iancu, E.
name: Triantafyllopoulos, D. N.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study multi-particle production with rapidity correlations in proton-nucleus collisions at high energy in the Color Glass Condensate framework. The high-energy evolution responsible for such correlations is governed by a generalization of the JIMWLK equation describing the simultaneous evolution of the strong nuclear color fields in the direct amplitude and the complex conjugate amplitude. This functional equation can be used to derive ordinary evolution equations for the cross-sections for particle production, but the ensuing equations appear to be too complicated to be useful in practice, including in the limit of a large number of colors Nc. We propose an alternative formulation based on a Langevin process, which is valid for generic Nc and is better suited for numerical implementations. For illustration, we present the stochastic equations which govern two gluon production with arbitrary rapidity separation.
description: 8 pages, 6 figures, based on talk given at IS 2013, 8 - 14 Sep 2013, Illa da Toxa, Spain
title: L'expérience de l'oeuvre d'art originale modifie-t-elle la perception qu'en ont les élèves ?
title: L'expérience de l'oeuvre d'art originale modifie-t-elle la perception qu'en ont les élèves ?
titleType: AlternativeTitle
Creators: name: Tosi, Arnaud
Publisher: name: Unknown
Year: 0
Subjects: subject: oeuvre d’art originale
subject: perception
subject: aura
subject: expérience
subject: rapport affectif
subject: gravure

description: Ce mémoire professionnel tend à interroger le rapport que des élèves du secondaire 1 entretiennent avec des oeuvres d’art originales. Ce rapport se décline sous divers aspects traduits en questionnements: ont-ils une expérience préalable des oeuvres, lorsqu’ils sont en contact avec des oeuvres quel est leur ressenti et cette mise en contact influence elle la perception qu’ils en ont tant d’un point de vue esthétique qu’artistique. Cette problématique professionnelle et les questionnements qu’elle génère, s’inscrivent dans les axes du PER : - A34AV Comparer et analyser différentes oeuvres artistiques… (Découverte et approche d'artistes de sa région, privilégier un contact direct avec les oeuvres et les artistes (rencontres, ateliers, oeuvres originales,…)) - A32AV Analyser ses perceptions sensorielles en mobilisant son ressenti (confronter ses propres perceptions avec celles des autres artistes et/ou camarades pour élargir et remettre en question les siennes). En profitant de l’exposition dans un collège d’oeuvres originales issu du Fonds des Oeuvres d’Art Contemporain de la didactique des arts visuels de la Haute Ecole Pédagogique Vaud, j’ai mis en place une activité avec deux classes du secondaire. Les élèves ont découvert et observé les oeuvres en collectif puis en individuel, et ont expérimenté une activité de gravure. Un questionnaire recueillait leurs impressions et réactions aux différentes étapes de l’expérience. L’analyse des réponses franches et honnêtes apportées par les élèves permet de mieux comprendre leur rapport aux oeuvres d’art et l’expérience qu’ils en font. Elles répondent à certaines de mes interrogations, et en ont ouvert quantité d’autres. Le puissant aspect affectif et émotionnel que les élèves ressentent au contact des oeuvres permet également d’envisager des pistes de travail possibles en classe ou plus loin.
RECQL4: linking DNA replication to bone tumorigenesis
Creators: name: Chacko, Lisa
Publisher: name: University of Lincoln
Year: 2023

description: RECQL4 is a gene that encodes a 1208 amino acid protein. RECQL4 protein is required duringDNA replication initiation and DNA end resection. A lack of RECQL4 is therefore associatedwith a decrease in DNA damage repair. There are three unrelated autosomal recessivediseases that are linked with mutations in RECQL4. Rothmund Thomson Syndrome is raredisorder which has documented mutations within RECQL4 which has been linked to anincreased tendency to develop osteosarcomas.To study the effect of RECQL4 depletion, shRNA knockdowns, ASC52Telo cells, osteodifferentiated cells and osteo-differentiated cells in long term PHA-767491 treatment weresubjected to a series of experiments. The trilineage differentiation capability, growthcharacteristics, expression of cell proliferation and bone formation markers, drug sensitivityand chromosomal instability was tested for each of the cell lines. These results could be usedto identify any differences in expressions and behaviours between the RECQL4 depleted cellsand the control cells.All the cell lines were able to differentiate into adipocytes and osteoblasts, with p44 pLK0.1and p44 shRQ-9 having a decreased adipocyte differentiation in comparison to the others. Nosignificant difference was observed in the growth assay between the cells in which RECQL4was depleted and their controls. The p44 shRQ-9 cells showed the lowest foci count whentested for 53BP expression but the highest Ki67 expression. There were no significant resultsbetween the RECQL4 depleted cells and their controls when looking at marker geneexpressions. The drug sensitivity assays also show no significant differences however p14shRQ-10 and P44 shRQ-10 appear less sensitive in the mid-range concentrations. Thechromosomal analysis showed that OD+PHA, p44 shRQ-9 and p44 shRQ-10 have an increaseddegree of aneuploidy and tetraploid cells.
A Stable Numerical Algorithm for the Brinkman Equations by Weak Galerkin Finite Element Methods
Creators: name: Mu, Lin
name: Wang, Junping
name: Ye, Xiu
Publisher: name: arXiv
Year: 2013
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: Primary, 65N15, 65N30, 76D07, Secondary, 35B45, 35J50

description: This paper presents a stable numerical algorithm for the Brinkman equations by using weak Galerkin (WG) finite element methods. The Brinkman equations can be viewed mathematically as a combination of the Stokes and Darcy equations which model fluid flow in a multi-physics environment, such as flow in complex porous media with a permeability coefficient highly varying in the simulation domain. In such applications, the flow is dominated by Darcy in some regions and by Stokes in others. It is well known that the usual Stokes stable elements do not work well for Darcy flow and vise versa. The challenge of this study is on the design of numerical schemes which are stable for both the Stokes and the Darcy equations. This paper shows that the WG finite element method is capable of meeting this challenge by providing a numerical scheme that is stable and accurate for both Darcy and the Stokes dominated flows. Error estimates of optimal order are established for the corresponding WG finite element solutions. The paper also presents some numerical experiments that demonstrate the robustness, reliability, flexibility and accuracy of the WG method for the Brinkman equations.
description: 20 pages, 21 plots and figures
The Role of OPACs in Users’ Social interactivity: Current Strategies and the Extent to which University OPACs Follow them
Publisher: name: Iranian Research Institute for Information Science and Technology (IranDoc)
Year: 2015

description: OPACs are regarded as one of the most important intermediaries between library users and their collections. Through them one can find, identify and access desired information resources. A while ago, the very nature of OPACs made holdings of libraries and information centers available throughout the world but the real interaction between users and the collection was far beyond reach. Now through new technologies, such as Web 2.0, Library 2.0 and OPAC 2.0, a higher level of user interaction is possible. The first part of this paper identified a set of OPAC 2.0 elements. A checklist was prepared based on these elements, then using it, 7 different OPAC softwares were assessed. Among the studied OPACs, “Sana” was identified as the most successful OPAC in both searching and social facilities. Regarding these social facilities, “ParsAzarakhsh” and “Parvan” were in a rather good state. Moreover, “Oracle”, “Parvan” and “Payam” were in a fairly poor state for the searching facilities and “Simorgh functionality was not acceptable when social facilities were considered. The overall score of all these OPACs was higher in searching than social facilities.
Functional Morphology of Stereospondyl Amphibian Skulls
Creators: name: Penrice, Samantha
Publisher: name: University of Lincoln
Year: 2023

description: Stereospondyls were the most diverse clade of early tetrapods, spanning 190 millionyears, with over 250 species belonging to eight taxonomic groups. They had a range ofmorphotypes and have been found on every continent. Stereospondyl phylogeny is widelycontested and repeatedly examined but despite these studies, we are still left with thequestion, why were they so successful and why did they die out? A group-wide analysisof functional morphology, informing us about their palaeobiology, was lacking for thisgroup and was carried out in order to address the questions of their success and demise.Based on an original photograph collection, size independent skull morphometrics wereused, in conjunction with analyses of the fossil record and comparative anatomy, toprovide a synthesis of the functional morphology of stereospondyl amphibians.Stereospondyls originated in the Carboniferous and most taxonomic groups were extinctat the end of the Triassic. The early Triassic had exceptionally high numbers of shortlived genera, in habitats that were mostly arid but apparently experienced occasionalmonsoon rains. Genera turnover slowed and diversity was stable in the Middle Triassic,then declined with a series of extinctions of the Late Triassic. Stereospondyls showed thepattern of ‘disaster’ taxa: rapidly diversifying following a mass extinction, spreading to aglobal distribution, although this high diversity was relatively short-lived.Geometric morphometrics on characteristics of the skull and palate was carried out toassess general skull morphology and identified the orbital position and skull outline to bethe largest sources of skull variation. Comparing anatomy of stereospondyls with extantspecies revealed that the differences in head shape and orbit positions betweenstereospondyls allows inference of a range of feeding behaviours, ranging from rapid headswipes, to crushing invertebrates with wide palatal bones, and crocodilian-typeambushing. The range of feeding modalities meant stereospondyl species were able tocoexist with minimal competition. The success was, however, short lived, as highlyspecialised shapes in the middle and Late Triassic probably meant that stereospondylswere not able to adapt to a more generalised lifestyle when the end Triassic extinctioneliminated ecosystems.