cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Spontaneous cell cycle synchronisation
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2017
Subjects: subject: 29901 Biological Physics
subject: FOS: Biological sciences
subject: Cell Biology
subject: 60103 Cell Development, Proliferation and Death
subject: 60402 Cell and Nuclear Division
subject: 29902 Complex Physical Systems
subject: FOS: Physical sciences

description: We suggest that it may be possible for the cell cycles of neighboring biological cells to become spontaneously synchronized, e.g., in the presence of defects or disease. We are not proposing that spontaneous synchronization of cycles between neighboring cells is necessarily common or permanent. Rather, we suggest that temporary islands or “domains” of cells with synchronized cell cycles can form and exhibit collective behavior for some time, before disappearing. We suggest that a cell with faulty DNA whose cycle is synchronized with those of surrounding healthy cells may be dragged past the G1/S and G2/M checkpoints even if, in isolation, it would be stalled to allow repair or marking for apoptosis.
Bewertung von Informationsquellen
Creators: name: Grahl, Tina
Publisher: name: Zenodo
Year: 2022

description: Bei der Recherche ist es wichtig die gefundenen Dokumente zu begutachten, egal ob es sich um gedruckte oder elektronische Publikationen handelt. Begutachten Sie zuerst die bibliographischen Angaben (Autor, Titel, Verlag, Jahr etc.) der Publikation.
Additional file 2 of Aligning intuition and theory: enhancing the replicability of behaviour change interventions in cancer genetics
Creators: name: Taylor, Natalie
name: Healey, Emma
name: Morrow, April
name: Greening, Sian
name: Wakefield, Claire E.
name: Warwick, Linda
name: Williams, Rachel
name: Tucker, Katherine M.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 2: Supplementary File 2. Mapping intuitively derived barriers and interventions to the TDF and BCTs.
Additional file 1 of Long noncoding RNA Linc00337 functions as an E2F1 co-activator and promotes cell proliferation in pancreatic ductal adenocarcinoma
Creators: name: Wang, Huakai
name: Yu, Shiyong
name: Peng, Huan
name: Shu, Yijun
name: Zhang, Wenjie
name: Zhu, Qi
name: Wu, Yingxia
name: Xu, Yijun
name: Yan, Jiqi
name: Xiang, Honggang
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Virology

description: Additional file 1: Figure S1. Box plots depicting the expression of 20 cancer-associated lncRNAs in PDAC and normal tissues. TCGA data was analyzed using the GEPIA website (http://gepia.cancer-pku.cn/index.html). Figure S2. Overall survival analysis of the expression of 20 cancer-associated lncRNAs in PDAC. TCGA data was analyzed using the GEPIA website (http://gepia.cancer-pku.cn/index.html). Figure S3. RNA decay curves depicting the degradation of mRNAs. 18S was used as a reference gene and no significant alterations were observed following Actinomycin D treatment. Data represent the mean ± SD of three independent experiments. Figure S4. a, RPISeq prediction parameters of Linc00337 and E2F1 binding. b, western blot analysis of Flag-E2F1 immunoprecipitation, DP1 as positive control and GAPDH as negative control. c, qRT-PCR analysis of Linc00337 and GAPDH enrichment in PANC1 cells by Lac Z and 337.
Synthesis of brassinosteroids analogues from laxogenin and their plant growth promotion
Creators: name: Wang, Qi
name: Xu, Jing
name: Liu, Xiaoli
name: Gong, WenXiu
name: Zhang, Cunli
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Genetics
subject: Biochemistry

description: Four steroid saponins (2–5) and three derivatives (6–8) were synthesised from laxogenin. Four of them were new compounds: (25R)-3β-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyloxy)-5α-spirostan-6-one (3), (25R)-3β-(β-d-galactopyranosyloxy)-5α-spirostan-6-one (5), 3β,16-diacetyl-26-hydroxy-5α-cholestan-6,22-dione (6) and 16-acetyl-3β,26-dihydroxy-5α-cholestan-6,22-dione (7). All the compounds showed plant growth-promoting activity in the radish hypocotyl elongation and cotyledon expansion bioassay. Above all, 2 and 6 were found to be more active.
Assessing Price Sensitivity of Forest Recreational Tourists in a Mountain Destination
Creators: name: Grilli, Gianluca
name: Grilli, Gianluca
Publisher: name: Unknown
Year: 2020
Subjects: subject: Demand and Price Analysis
subject: Travel cost
subject: forest recreation
subject: price elasticity
subject: Carpathians
subject: rural development

description: Despite the large use of the travel cost method as estimation technique for the demand for forest recreation, information on price elasticity is only seldom reported. In this way, it is hard to understand if a large consumer surplus could be reflected in income opportunities for the local populations, because it is unknown whether the number of annual trips will decrease as a consequence of price changes. This is particularly relevant in remote rural areas, where few other opportunities for additional earnings are available. This contribution attempts to fill this gap, estimating price elasticities for two different specifications of the cost for travel; a first specification includes cost for travel only, while the second comprise on-site expenditures (such as food and accommodation). Data were collected by means of a questionnaire survey administrated to a sample of local visitors and analysed with a Poisson model. Results suggest that visitors have different sensitivities to distance travelled and to expenses locally sustained, the first being more elastic.
Additional file 1 of Cancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)
Creators: name: Lee, Sang-Yun
name: Cho, Hyeong Jun
name: Choi, Jimin
name: Ku, Bosung
name: Moon, Seok Whan
name: Moon, Mi Hyoung
name: Kim, Kyung Soo
name: Hyun, Kwanyong
name: Kim, Tae-Jung
name: Sung, Yeoun Eun
name: Hwang, Yongki
name: Lee, Eunyoung
name: Ahn, Dong Hyuck
name: Choi, Joon Young
name: Lim, Jeong Uk
name: Park, Chan Kwon
name: Kim, Sung Won
name: Kim, Seung Joon
name: Koo, In-Seong
name: Jung, Woo Seok
name: Lee, Sang-Hyun
name: Yeo, Chang Dong
name: Lee, Dong Woo
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1: Figure S1. Summary of Illustration and Limitations for the Conventional 3D-Cell Spotter. (A) A conventional stainless nozzle-type cell spotter that dispenses samples with the pressure of a syringe pump. A dead volume of 50 μL or more is required to dispense high-viscosity samples. In addition, a nozzle-washing process is required to prevent cross-contamination whenever a sample is changed. Figure S2. Comparison of Patient-derived Cell Preparation Methods by Enzymatic and Mechanical Dissociation. (A) Image of organoid culture and proliferation rate difference analysis according to enzymatic and mechanical dissociation methods. (B) Quantitative analysis of differences in lung cancer organoid growth rates according to different dissociation methods through 3D live cell-staining. Figure S3. Results of CODRP index-based drug sensitivity test for each ALK-targeted drug. Drug response to three types of ALK-targeted drugs; (A) crizotinib, (B) alectinib and (C) brigatinib was analyzed into sensitive and resistant areas according to the ALK status of PDOs. Table S1. Cancer stage scoring standard table and individual patient’s cancer stage, growth rate, AUC, AUC Index, and CODRP Index. Table S2. Scoring table of cancer stage for CODRP index. Table S3. Recipe of the lung cancer PDO culture media. Table S4. Summary information of lung cancer patient-derived samples and dissociated PDC (viability and total cell number). Table S5. Summary of pathology analysis. Table S6. Summary of clinical information. Table S7. Summary of multiple linear regression (MLR) analysis results
Spontaneous cell cycle synchronisation
Creators: name: Highmore, Roger
Publisher: name: figshare
Year: 2018
Subjects: subject: 29901 Biological Physics
subject: FOS: Biological sciences
subject: Cell Biology
subject: 60103 Cell Development, Proliferation and Death
subject: 60402 Cell and Nuclear Division
subject: 29902 Complex Physical Systems
subject: FOS: Physical sciences

description: We suggest that it may be possible for the cell cycles of neighboring biological cells to become spontaneously synchronized, e.g., in the presence of defects or disease. We are not proposing that spontaneous synchronization of cycles between neighboring cells is necessarily common or permanent. Rather, we suggest that temporary islands or “domains” of cells with synchronized cell cycles can form and exhibit collective behavior for some time, before disappearing. We suggest that a cell with faulty DNA whose cycle is synchronized with those of surrounding healthy cells may be dragged past the G1/S and G2/M checkpoints even if, in isolation, it would be stalled to allow repair or marking for apoptosis.
Synchronisation may occur if cell cycle oscillations are coupled with receipt and transmission of messages at cell membranes. Storms of inter-cell messages could cause collaborative cell cycling and synchronised cell growth, which may in turn make it easier for clusters of cells to cycle together than it is for lone cells to cycle in isolation.
One Word: Navier-Stokes..pdf
Creators: name: Wright, Nicholas R.
Publisher: name: figshare
Year: 2019
Subjects: subject: 50102 Ecosystem Function
subject: FOS: Earth and related environmental sciences
subject: 10111 Real and Complex Functions (incl. Several Variables)
subject: FOS: Mathematics
subject: 10108 Operator Algebras and Functional Analysis
subject: 10202 Biological Mathematics
subject: 10205 Financial Mathematics
subject: 10599 Mathematical Physics not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified

description: We prove the Navier-Stokes equations, by means of the Metabolic Theory of Ecology and the Rule of 72. Macroecological theories are proof to the Navier-Stokes equations. A solution could be found using Kleiber’s Law. Measurement is possible through the heat calorie. A Pareto Improvement exists within the Navier-Stokes equations. This is done by superposing dust solutions onto fluid solutions. In summary, the Navier-Stokes equations require a theoretical solution. The Metabolic Theory of Ecology, along with Kleiber’s Law, form a theory by such standards.
Supplementary and Source Data relating to a correction to Kolas et al. Science. (2007) 318(5856):1637–1640
Creators: name: Durocher, Daniel
Publisher: name: Zenodo
Year: 2025

description: Supplementary and Source Data for the corrigendum for Figure 3D in Kolas et al. Science. 2007 Nov 15;318(5856):1637–1640. doi: 10.1126/science.1150034

First read Kolas corrigendum text.docx Contains legends for the revised Figure 3D, Supplementary Figure 1, and Supplementary Movies. It also contains revised methods.Other files include:

Supplementary Figure 1 (Sup Figure 1.pdf)Source Data Table 1Supplementary Movies 1-4Microscopy acquision files in .nd2 formatFiles are labled per replicate (rep2, rep3 and rep5) and file numbers.Please refer to each read me files to find what conditions correspond to which file number.

Scans of the blots used in Sup Fig 1BBlot Source Data 1.jpgBlot Source Data 2.jpg

Scripts for foci analysisFoci Count.cppipeLabel timelapse.ijmStardist Mask.ijmSplit channels.ijm
Additional file 1 of Resection of the primary tumor improves the prognosis of gastrointestinal neuroendocrine neoplasms with liver metastases: mutual validation based on SEER database and institutional data
Creators: name: Liu, Yifan
name: Wang, Zhixiong
name: Lin, Qi
name: Cui, Ruizhe
name: Tang, Wei
name: Li, Guanghua
name: Wang, Zhao
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1.
Dialéctica, direito e teologia: Alberico da Rosciate e Álvaro Pais
Creators: name: Silva, Nuno Espinosa Gomes Da
Publisher: name: Didaskalia
Year: 2003

description: Didaskalia, v. 33 n. 1-2 (2003): In Memoriam Professor Doutor P. Manuel Isidro Araújo Alves
Synthesis, characterization, DNA interaction, and in vitro cytotoxicity activities of two ruthenium(II) complexes with disubstituted 2,2′-dipyridyl ligands bearing ammonium groups
Creators: name: Sun, Jing
name: Chen, Wen-Xiu
name: Song, Xing-Dong
name: Zhao, Xuan-Hao
name: Ma, Ai-Qing
name: Chen, Jia-Xi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Cell Biology
Engineering
Biochemistry
Biophysics

description: The DNA binding, cleavage, and cytotoxic properties of two new Ru(II) complexes [Ru(bpy)2L](PF6)4 (L: L1 = (5,5′-((n-Me)3NCH2)2-bpy)2+; L2 = (5,5′-((n-Et)3NCH2)2-bpy)2+) have been investigated. The results show that both Ru(II) complexes bind to DNA through an electrostatic binding mode. The binding affinity constant can reach 104 M−1 and 1 has a higher binding affinity than 2. Equilibrium dialysis experiments revealed that the complexes are candidates for enantioselective binding to CT-DNA. Moreover, further analysis of the ruthenium complexes revealed that 1 has a higher and more efficient DNA cleavage activity than 2. In vitro cytotoxicity studies of both complexes showed that they exhibited moderate antitumor activity against HeLa, A549, and CNE-2 cancer cells. In addition, 2 displayed higher in vitro cytotoxicity than 1.
A comprehensive observational audit tool for use in Australian fitness facilities
Creators: name: Gray, Shannon
name: Betul Sekendiz
name: Norton, Kevin
name: Finch, Caroline
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Cancer

description: A purposely designed observational audit tool (OAT) was developed following review of literature and international standards/guidelines for fitness facilities. The OAT was trialled to assess the physical environment of a sample of fitness facilities and determine its inter-rater reliability. Ten Victorian fitness facilities were visited to test the tool's inter-rater reliability, then 22 metropolitan and regional facilities in Victoria ranging in size and type were audited. A high degree of reliability was found (inter-rater reliability κ = 0.659 (p < 0.005); 95% CI (0.633, 0.685)); intra-class correlation = 0.985 (F474,948 = 67.226, p < 0.005, 95% CI (0.983, 0.987)). On average, facilities were colder and darker than international standards/guidelines specified. Distances around cardiovascular equipment varied between facilities. Free equipment was observed lying on floors in 66% (n = 21) of facilities. Twenty-seven facilities had signs instructing users to replace weights after use (66%). Only 19 (59%) facilities enforced towel use; however, 94% (n = 30) had disinfectant stations. The auditing of fitness facilities indicates more should be done at facilities to reduce injury risk.
The last Syme : Ranald Macdonald's impact on the Age newspaper, Melbourne, 1964-1983
Creators: name: Tidey, John Newton.
Publisher: name: Monash University
Year: 2023
Subjects: classificationCode: 430302
subject: Australian history

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Additional file 1 of Targeted delivery of organic small-molecule photothermal materials with engineered extracellular vesicles for imaging-guided tumor photothermal therapy
Creators: name: Dong, Yafang
name: Xia, Peng
name: Xu, Xiaolong
name: Shen, Jing
name: Ding, Youbin
name: Jiang, Yuke
name: Wang, Huifang
name: Xie, Xin
name: Zhang, Xiaodong
name: Li, Weihua
name: Li, Zhijie
name: Wang, Jigang
name: Zhao, Shan-Chao
Publisher: name: figshare
Year: 2023
Subjects: Biochemistry
Space Science
Physical Sciences not elsewhere classified
Medicine
Cell Biology
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer

description: Supplementary Material 1
A Brief Solution to the Riemann Hypothesis over the Lagarias Transformation
Creators: name: Kavak, Mesut
Publisher: name: figshare
Year: 2018
Subjects: subject: 10101 Algebra and Number Theory
subject: FOS: Mathematics
subject: 10207 Theoretical and Applied Mechanics
subject: 10301 Numerical Analysis
subject: 10404 Probability Theory
subject: Probability
subject: 10405 Statistical Theory

description: This work aims to bring a simple solution out to the Riemann Hypothesis over the Lagarias transformation.
Synthesis, characterization, DNA interaction and in vitro cytotoxicity activities of two ruthenium(II) complexes with disubstituted 2,2’-dipyridyl ligands bearing ammonium groups
Creators: name: Sun, Jing
name: Chen, Wen-Xiu
name: Song, Xing-Dong
name: Zhao, Xuan-Hao
name: Ma, Ai-Qing
name: Chen, Jia-Xi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Cell Biology
Engineering
Biochemistry
Biophysics

description: The DNA binding, cleavage, and cytotoxic properties of two new Ru(II) complexes [Ru(bpy)2L](PF6)4 (L: L1 = (5,5’-((n-Me)3NCH2)2-bpy)2+; L2 = (5,5’-((n-Et)3NCH2)2-bpy)2+) have been investigated. The results show that both Ru(II) complexes bind to DNA through an electrostatic binding mode. The binding affinity constant can reach 104 M−1 and 1 has a higher binding affinity than 2. Equilibrium dialysis experiments revealed that the complexes are candidates for enantioselective binding to CT-DNA. Moreover, further analysis of the ruthenium complexes revealed that 1 has a higher and more efficient DNA cleavage activity than 2. In vitro cytotoxicity studies of both complexes showed that they exhibited moderate antitumor activity against HeLa, A549, and CNE-2 cancer cells. In addition, 2 displayed higher in vitro cytotoxicity than 1.
Additional file 1 of Understanding factors associated with the trajectory of subjective cognitive complaints in groups with similar objective cognitive trajectories
Creators: name: Cacciamani, Federica
name: Bercu, Ariane
name: Bouteloup, Vincent
name: Grasset, Leslie
name: Planche, Vincent
name: Chêne, Geneviève
name: Dufouil, Carole
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mental Health
subject: Computational Biology

description: Additional file 1. Full list of the MEMENTO Study Group.
Synthesis, characterization, DNA interaction, and in vitro cytotoxicity activities of two ruthenium(II) complexes with disubstituted 2,2′-dipyridyl ligands bearing ammonium groups
Creators: name: Sun, Jing
name: Chen, Wen-Xiu
name: Song, Xing-Dong
name: Zhao, Xuan-Hao
name: Ma, Ai-Qing
name: Chen, Jia-Xi
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Cancer
Biological Sciences
Chemistry
Earth and Environmental Sciences
Cell Biology
Engineering
Biochemistry
Biophysics

description: The DNA binding, cleavage, and cytotoxic properties of two new Ru(II) complexes [Ru(bpy)2L](PF6)4 (L: L1 = (5,5′-((n-Me)3NCH2)2-bpy)2+; L2 = (5,5′-((n-Et)3NCH2)2-bpy)2+) have been investigated. The results show that both Ru(II) complexes bind to DNA through an electrostatic binding mode. The binding affinity constant can reach 104 M−1 and 1 has a higher binding affinity than 2. Equilibrium dialysis experiments revealed that the complexes are candidates for enantioselective binding to CT-DNA. Moreover, further analysis of the ruthenium complexes revealed that 1 has a higher and more efficient DNA cleavage activity than 2. In vitro cytotoxicity studies of both complexes showed that they exhibited moderate antitumor activity against HeLa, A549, and CNE-2 cancer cells. In addition, 2 displayed higher in vitro cytotoxicity than 1.
The future of Bio-Based and Applied Economics
Creators: name: Moro, Daniele
name: Santeramo, Fabio Gaetano
name: Viaggi, Davide
name: Moro, Daniele
name: Santeramo, Fabio Gaetano
name: Viaggi, Davide
Publisher: name: Unknown
Year: 2020
Subjects: Teaching/Communication/Extension/Profession

description: Editorial
Separation and identification of ACE inhibitory peptides from cashew nut (Anacardium occidentale Linnaeus) protein
Creators: name: Guang-Long Yao
name: Chai, Yu
name: Chen, Jian
name: You-Gen Wu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 60506 Virology

description: Cashew nut protein powder was hydrolysed by alkaline protease to prepare ACE inhibitory peptides. Results showed that the optimum conditions were: substrate concentration, 7 g/100 mL; amount of enzyme, 3%; pH, 10.5; hydrolysis time, 6 h; and temperature, 45°C. Under these conditions, ACE inhibitory rate was 57.45%. ACE inhibitory peptides were filtered using an ultrafiltration membrane of different molecular weights and Sephadex G-15 gel column. We found that the molecular weight was <3000 Da, and the ACE inhibitory rate concentration was 100 mg/mL. The M2 component, which was the most active component in ACE inhibitory peptides, yielded an ACE inhibitory rate of 77.58%. The M2 component contained 18 types of amino acids, including seven types of essential amino acids with the highest proline content reaching 23.56% (P < 0.01). The molecular weight of the M2 constituent was observed as 389 Da, with an amino acid sequence of Glu- Ser - Arg.
A Brief Approach to the Riemann Hypothesis Over the Lagarias Transformation
Creators: name: Kavak, Mesut
Publisher: name: figshare
Year: 2017
Subjects: subject: 10101 Algebra and Number Theory
subject: FOS: Mathematics
subject: 10207 Theoretical and Applied Mechanics

description: This works aims to bring a simple solution to the Riemann Hypothesis over the Lagarias transformation.
Dual Role of Alkynyl Bromides in One-Step Synthesis of Bromo-Substituted Alkynyl Sulfides
Creators: name: Yang, Yuan
name: Huang, Hui
name: Liu, Wei
name: Liang, Yun
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Developmental Biology
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Biotechnology
subject: Molecular Biology
subject: Biochemistry
subject: Biophysics

description: An atom-economical and environmentally friendly method for synthesis of bromo-substituted alkynyl sulfides has been developed. In the absence of any additive, alkynyl bromides could react with tetrahydrothiophene to give bromo-substituted alkynyl sulfides in moderate to perfect yields.
Separation and identification of ACE inhibitory peptides from cashew nut (Anacardium occidentale Linnaeus) protein
Creators: name: Guang-Long Yao
name: Chai, Yu
name: Chen, Jian
name: You-Gen Wu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 60506 Virology

description: Cashew nut protein powder was hydrolyzed by alkaline protease to prepare ACE inhibitory peptides. Results showed that the optimum conditions were: substrate concentration, 7 g/100 mL; amount of enzyme, 3%; pH, 10.5; hydrolysis time, 6 h; and temperature, 45°C. Under these conditions, ACE inhibitory rate was 57.45%. ACE inhibitory peptides were filtered using an ultrafiltration membrane of different molecular weights and Sephadex G-15 gel column. We found that the molecular weight was <3000 Da, and the ACE inhibitory rate concentration was 100 mg/mL. The M2 component, which was the most active component in ACE inhibitory peptides, yielded an ACE inhibitory rate of 77.58%. The M2 component contained 18 types of amino acids, including seven types of essential amino acids with the highest proline content reaching 23.56%（P<0.01）. The molecular weight of the M2 constituent was observed as 389 Da,with an amino acid sequence of Glu- Ser - Arg.
O Panegírico de Trajano: modelo do Panegírico de D. João III do humanista João de Barros
Creators: name: Couto, Aires Pereira Do
Publisher: name: Didaskalia
Year: 2003

description: Didaskalia, v. 33 n. 1-2 (2003): In Memoriam Professor Doutor P. Manuel Isidro Araújo Alves
Reducing carbon: phosphorus ratio can enhance microbial phytin mineralization and lessen competition with maize for phosphorus
Creators: name: Zhang, Lin
name: Ding, Xiaodong
name: Chen, Sanfeng
name: He, Xinhua
name: Zhang, Fusuo
name: Feng, Gu
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology

description: We tested the hypothesis that reducing the carbon (C):Phosphorus (P) ratio in rhizosphere soil would reduce bacterial competition with the plant for P from phytin, which would then increase phytin use efficiency for the plant. A three-factor pot experiment was carried out to study the effect of inoculation with a phytin-mineralizing bacterium, Pseudomonas alcaligenes (PA), on maize P uptake from phytin. Two levels of organic P, two levels of inorganic P, and three different PA inoculation treatments were used. When maize plants were grown in low available P soil with phytin, PA transformed soil P into microbial biomass P, which caused competition for available P with plant and inhibited plant uptake. When 5 mg P kg−1 as KH2PO4 was added, inoculation with PA increased soil acid phosphatase activity which enhanced the mineralization rate of phytin. PA mobilized more P than it immobilized in microbial pool and enhanced plant P uptake. We conclude that the decreased C:P ratio by adding small amount of inorganic P in the rhizosphere could drive phytin mineralization by the bacteria and improve plant P nutrition.
Report of the 2017 NSF SI2 PI Meeting
Creators: name: Gopalakrishnan, Ganesh
name: Yung-Hsiang Lu
name: Knepley, Matthew
name: Niemeyer, Kyle
name: Turk, Matthew
name: Wilkins-Diehr, Nancy
Publisher: name: NSF-SI2-PI
Year: 2017
Subjects: subject: Computer Software
subject: FOS: Computer and information sciences
subject: 80309 Software Engineering
subject: 80306 Open Software

description: This report describes the 2017 NSF Software Infrastructure for Sustained Innovation (SI2) program PI workshop, held 21–22 February 2017 in Arlington, VA.
Reducing carbon : phosphorus ratio can enhance microbial phytin mineralization and lessen competition with maize for phosphorus
Creators: name: Zhang, Lin
name: Ding, Xiaodong
name: Chen, Sanfeng
name: He, Xinhua
name: Zhang, Fusuo
name: Feng, Gu
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Microbiology

description: We tested the hypothesis that reducing the carbon (C): Phosphorus (P) ratio in rhizosphere soil would reduce bacterial competition with the plant for P from phytin, which would then increase phytin use efficiency for the plant. A three-factor pot experiment was carried out to study the effect of inoculation with a phytin-mineralizing bacterium, Pseudomonas alcaligenes (PA), on maize P uptake from phytin. Two levels of organic P, two levels of inorganic P and three different PA inoculation treatments were used. When maize plants were grown in low available P soil with phytin, PA transformed soil P into microbial biomass P (MBP), which caused competition for available P with plant and inhibited plant uptake. When 5 mg P kg−1 as KH2PO4 was added, inoculation with PA increased soil acid phosphatase activity which enhanced the mineralization rate of phytin. PA mobilized more P than it immobilized in microbial pool and enhanced plant P uptake. We conclude that the decreased C: P ratio by adding small amount of inorganic P in the rhizosphere could drive phytin mineralization by the bacteria and improve plant P nutrition.
Additional file 1 of Impairments in sleep and brain molecular clearance in people with cognitive deterioration and biological evidence of AD: a report of four cases
Creators: name: Buongiorno, Mariateresa
name: Granell, Esther
name: Caruana, Giovanni
name: Sansa, Gemma
name: Vives-Gilabert, Yolanda
name: Cullell, Natalia
name: Molina-Seguin, Jessica
name: Almeria, Marta
name: Artero, Cristina
name: Sánchez-Benavides, Gonzalo
name: Ray, Nicola J
name: Correa, Sonia A.L.
name: Krupinski, Jerzy
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
Modification of ligands for serum albumin on polyethyleneimine to stabilize polyplexes in gene delivery
Creators: name: Nakamura, Yuta
name: Sato, Hikari
name: Takanobu Nobori
name: Hotaru Matsumoto
name: Toyama, Shoko
name: Shuno, Tomohiro
name: Kishimura, Akihiro
name: Mori, Takeshi
name: Katayama, Yoshiki
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: Plant Biology

description: In this work, we have developed a new technique to stabilize a ternary complex composed of plasmid DNA, a linear polyethyleneimine (LPEI) and serum albumin. A stearoyl group was conjugated to LPEI as a specific ligand for serum albumin. The resultant ternary complex has excellent stability in physiological saline conditions, maintaining its initial diameter and preventing aggregation of red blood cells. The ternary complex has equivalent transfection ability to and significantly lower cytotoxicity than unmodified LPEI. Therefore, the ternary complex is potentially useful as a new gene carrier, possessing high blood stability.
Degradation of polycyclic aromatic hydrocarbons in crumb tyre rubber catalysed by rutile TiO2 under UV irradiation
Creators: name: Yu, Kai
name: Huang, Linyue
name: Lou, Lan-Lan
name: Chang, Yue
name: Dong, Yanling
name: Wang, Huan
name: Liu, Shuangxi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biotechnology
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Engineering
subject: Biochemistry

description: The polycyclic aromatic hydrocarbons (PAHs) in crumb tyre rubber were firstly degraded under UV irradiation in the presence of rutile TiO2 and hydrogen peroxide. The effects of light intensity, catalyst amount, oxidant amount, initial pH value, co-solvent content, and reaction time on degradation efficiency of typical PAHs in crumb tyre rubber were studied. The results indicated that UV irradiation, rutile TiO2, and hydrogen peroxide were beneficial to the degradation of PAHs and co-solvent could accelerate the desorption of PAHs from crumb tyre rubber. Up to 90% degradation efficiency of total 16 PAHs could be obtained in the presence of rutile TiO2 (1 wt%) and hydrogen peroxide (1.0 mL) under 1800 µW cm−2 UV irradiation for 48 h. The high molecular weight PAHs (such as benz(a)pyrene) were more difficult to be degraded than low molecular weight PAHs (such as phenanthrene, chrysene). Moreover, through the characterization of reaction solution and degradation products via GC–MS, it was proved that the PAHs in crumb tyre rubber were successfully degraded.
Degradation of polycyclic aromatic hydrocarbons in crumb tire rubber catalyzed by rutile TiO2 under UV irradiation
Creators: name: Yu, Kai
name: Huang, Linyue
name: Lou, Lan-Lan
name: Chang, Yue
name: Dong, Yanling
name: Wang, Huan
name: Liu, Shuangxi
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biotechnology
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Engineering
subject: Biochemistry

description: The polycyclic aromatic hydrocarbons (PAHs) in crumb tire rubber were firstly degraded under UV irradiation in the presence of rutile TiO2 and hydrogen peroxide. The effects of light intensity, catalyst amount, oxidant amount, initial pH value, co-solvent content, and reaction time on degradation efficiency of typical PAHs in crumb tire rubber were studied. The results indicated that UV irradiation, rutile TiO2, and hydrogen peroxide were beneficial to the degradation of PAHs and co-solvent could accelerate the desorption of PAHs from crumb tire rubber. Up to 90% degradation efficiency of total 16 PAHs could be obtained in the presence of rutile TiO2 (1 wt%) and hydrogen peroxide (1.0 mL) under 1800 μW cm-2 UV irradiation for 48 h. The high molecular weight PAHs (such as benz(a)pyrene) were more difficult to be degraded than low molecular weight PAHs (such as phenanthrene, chrysene). Moreover, through the characterization of reaction solution and degradation products via GC-MS, it was proved that the PAHs in crumb tire rubber were successfully degraded.Supplementary material
A falta médica na responsabilidade civil
Creators: name: Pina, José António Rebocho Esperança
Publisher: name: Didaskalia
Year: 1999

description: Didaskalia, v. 29 n. 1-2 (1999): In Honorem D. José Policarpo: Patriarca de Lisboa e Magno Chanceler da Universidade Católica Portuguesa
Statistische Daten recherchieren
Creators: name: Grahl, Tina
Publisher: name: Zenodo
Year: 2022

description: Statistische Daten können in wissenschaftlichen Arbeiten Thesen und Theorien festigen. Daten können durch Befragungen selbst erhoben oder in Fachdatenbanken recherchiert werden. Nutzen Sie bei recherchierten Daten bevorzugt die Primärquelle, d.h. die originale Quelle der Erhebung und achten Sie auf seriöse und aktuelle Datenquellen.
A Brief Approach to the Riemann Hypothesis Over the Lagarias Transformation
Creators: name: Kavak, Mesut
Publisher: name: figshare
Year: 2018
Subjects: subject: 10101 Algebra and Number Theory
subject: FOS: Mathematics
subject: 10207 Theoretical and Applied Mechanics
subject: 10301 Numerical Analysis
subject: 10404 Probability Theory
subject: Probability
subject: 10405 Statistical Theory

description: This works aims to bring a simple solution out to the Riemann Hypothesis over the Lagarias transformation.
A ratio studiorum do Colégio das Artes, nos primeiros anos em que esteve sob orientação da Companhia de Jesus (1555-1561)
Creators: name: Toipa, Helena Maria Ribeiro Costa
Publisher: name: Didaskalia
Year: 2003

description: Didaskalia, v. 33 n. 1-2 (2003): In Memoriam Professor Doutor P. Manuel Isidro Araújo Alves
title: Professor Dr. Ernst Brandenberger 1906-1966
title: Professor Dr. Ernst Brandenberger, 1906-1966
titleType: AlternativeTitle
Creators: name: Vogelsanger, Peter
name: Schumacher, Edgar
name: Uhlmann, Ernst
name: Amstutz, Eduard
Publisher: name: Zentralbibliothek Zürich
Year: 1966
Subjects: subject: 920 Biografien, Genealogie, Insignien
subject: Nachruf
subject: Zürich

description: Nekrolog
Dynamic pricing in the presence of strategic consumers with ‘experience-in-store-and-buy-online’
Creators: name: Cao, Erbao
name: Luo, Haodong
name: Ma, Yuan
name: Lü, Kevin
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Evolutionary Biology
subject: Ecology
subject: Astronomical and Space Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plasma Physics
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Experience-in-store-and-buy-online (ESBO) is a popular omni-channel strategy. This paper studies the effects of inspection service provision on the interactions of a dynamic-pricing retailer and strategic consumers, i.e., the effects of the ESBO initiative on store operations. Selling a seasonal product over two periods, the omni-channel retailer may allow consumers to inspect this product offline only in the first period (first-period inspection) or in both periods (two-period inspection). First, we find that allowing first-period inspection makes the retailer better off. The retailer will price the product higher in the first period but probably lower in the second period. Even so, more consumers will purchase in the first period: that is, allowing first-period inspection can somewhat deter strategic deferral. Meanwhile, the seemingly negative intertemporal showrooming behavior (i.e., inspect the product offline in the first period but defer online purchase to the second period) benefits the retailer. Compared to first-period inspection, allowing two-period inspection increases the retailer’s prices in both periods as well as profit, provided that inspection is definitely available in the second period. On the other hand, when inspection is possible in the second period, it may be profitable to allow inspection only in the first period..
Socio-economic effects of an earthquake: does sub-regional counterfactual sampling matter in estimates? An empirical test on the 2012 Emilia-Romagna earthquake
Creators: name: PAGLIACCI, Francesco
name: RUSSO, Margherita
Publisher: name: Dipartimento di Economia Marco Biagi - Universit� di Modena e Reggio Emilia
Year: 2016

description: Estimates of macroeconomic effects of natural disaster have a long tradition in economic literature (Albala-Bertrand, 1993a; 1993b; Tol and Leek, 1999; Chang and Okuyama, 2004; Benson and Clay, 2004; Str�mberg, 2007; UNISDR, 2009; Cuaresma, 2009; Cavallo and Noy, 2009; Cavallo et al., 2010; The United Nations and The World Bank, 2010). After the seminal contribution of Abadie et al. (2010) in identifying synthetic control groups, with DuPont and Noy (2015) a new strand has been opened in estimating long term effects of natural disaster at a sub-regional scale, at which the Japan case provides plenty of significant economic variables. Although the same methodology has been applied in estimating the impact of earthquakes in Italy (Barone et al. 2013; Barone and Mocetti, 2014), the analysis has been limited to the regional scale. In our paper, due to a lack in long-term time series data at municipality level, this paper cannot adopt the methodology suggested by Abadie et al. (2010). Nevertheless, it provides a test bed for assessing the relevance of a sub-regional counterfactual evaluation of a natural disaster?s impact.
By taking the 2012 Emilia-Romagna earthquake as a case study, we propose a comprehensive framework to answer some critical questions arising in such analysis. Firstly, we address the problem of identifying the proper boundaries of the area affected by an earthquake. Secondly, through a cluster analysis we show the importance of intra area differences in terms of their socio-economic features. Thirdly, counterfactual analysis is assessed by adopting a pre- and post-earthquake difference-in-difference comparison of average data in clusters within and outside the affected area. Moreover, three frames to apply propensity score matching at municipality level are also adopted, by taking the control group of municipalities (outside the affected area): (a) within the same cluster, (b) within the same region, (c) in the whole country. The four variables considered in the counterfactual analysis are: total population; foreigner population; total employment in manufacturing local units; employment in small and medium-sized manufacturing local units (0 to 49 employees). All the counterfactual tests largely show a similar result: socio-economic effects are heterogeneous across the affected area, where some clusters of municipalities perform better, in terms of increase of population and employment after the earthquake, against some others. This result sharply contrasts with the average results we observe by comparing the whole affected area with the non-affected one or with the entire region.
Study of Stimuli-Sensitivities of Amphiphilic Modified Star Poly[N,N-(Dimethylamino)ethyl Methacrylate] and Its Ability of DNA Complexation
Creators: name: Xue, Yan
name: Wei, Dafu
name: Zheng, Anna
name: Guan, Yong
name: Xiao, Huining
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Evolutionary Biology
subject: Biotechnology
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: Cationic star polymers as drug/gene carriers have attracted increasing attention. Herein, environmental sensitivities and star-shaped architecture were combined into a well-defined gene carrier system, and further amphiphilic modification was conducted. The thermo- and pH-sensitive behaviors of poly[N,N-(dimethyl amino)ethyl methacrylate] (PDMAEMA) star polymers before and after amphiphilic modification in aqueous solutions were investigated. The observed lower critical solution temperature (LCST) increased with increasing arm length due to the increase of hydrophilicity. A significant decrease of the LCSTs with increasing pH and ionic-strength of the solution was found. The incorporation of MMA and BA lipophilic moieties decreased the LCST of the cationic star polymer due to enhanced hydrophobic interaction. As a potential gene carrier, the performance of star polymers on binding DNA was primarily evaluated via particle size, zeta potential, and gel retardation measurements. All the complexes formed stable small particles with diameter of 100∼150 nm at N/P ratio higher than 3.0. The electrostatic screening effect and facilitation for the interaction of complexes with cell membrane induced by the incorporation of lipophilic units were expected to enhance the gene transfection efficiency.
Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233
Creators: name: Fredimoses, Mangaladoss
name: Zhou, Xuefeng
name: Ai, Wen
name: Tian, Xinpeng
name: Yang, Bin
name: Lin, Xiuping
name: Xian, Jia-Yun
name: Liu, Yonghong
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Hematology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Pharmacology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry

description: A new methyl 2-(4-((2-hydroxy-3-methylbut-3-en-1-yl)oxy)phenyl) acetate 1, together with five known compounds 2–6, was isolated from the culture of the deep sea-derived fungus Aspergillus westerdijkiae SCSIO 05233. The new structure was determined by NMR (1H and 13C NMR, HSQC, HMBC and MS) and optical rotation analysis. Compound 5 displayed weak inhibitory activities towards K562 and promyelocytic HL-60 with IC50 values of 25.8 and 44.9 μM, and compound 6 showed strong antifouling activity with EC50 value 8.81 μg/mL.
Additional file 1 of Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study
Creators: name: Luyt, Charles-Edouard
name: Hékimian, Guillaume
name: Bonnet, Isabelle
name: Bréchot, Nicolas
name: Schmidt, Matthieu
name: Robert, Jérôme
name: Combes, Alain
name: Aubry, Alexandra
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Supplementary Table S1. Pathogens detected by the Unyvero hospitalised-pneumonia (HPN) cartridge Supplementary Table S2. Resistance markers potentially detected by the HPN system and their target(s).
Two new flavonol glycosides from Dimocarpus longan leaves
Creators: name: Xue, Yongmei
name: Wang, Wenjing
name: Liu, Yujiao
name: Zhan, Rui
name: Chen, Yegao
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Developmental Biology
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Molecular Biology
subject: Genetics
subject: Microbiology
subject: Biochemistry

description: From the extracts of Dimocarpus longan Lour leaves, 2 unusual flavonol glycosides, quercetin 3-O-(3″-O-2‴-methyl-2‴-hydroxylethyl)-β-d-xyloside (1) and quercetin 3-O-(3″-O-2‴-methyl-2‴-hydroxylethyl)-α-l-rhamnopyranoside (2), as well as 10 known compounds including 2 flavonol glycosides, afzelin (3) and kaempferol-3-O-α-l-rhamnopyranoside (4), 2 flavans, ( − )-epicatechin (5) and proanthocyanidin A-2 (6), 3 triterpenoids, friedelin (7), epifriedelanol (8) and β-amyrin (9), a peptide, N-benzoylphenylalanyl-N-benzoylphenylalaninate (10), and 2 sterols, β-sitosterol (11) and daucosterol (12) were isolated and identified by using combination of mass spectrometry and various 1D and 2D NMR techniques. This is the first report of flavonoid glycosides possessing a 2-methyl-2-hydroxylethoxyl group in sugar moiety from D. longan.
A relação entre a ciência e a religião num mundo pós-moderno
Creators: name: Formosinho, Sebastião J.
Publisher: name: Didaskalia
Year: 1999

description: Didaskalia, v. 29 n. 1-2 (1999): In Honorem D. José Policarpo: Patriarca de Lisboa e Magno Chanceler da Universidade Católica Portuguesa