Additional file 1 of Interacting and joint effects of triglyceride-glucose index (TyG) and body mass index on stroke risk and the mediating role of TyG in middle-aged and older Chinese adults: a nationwide prospective cohort study
Creators: name: Huo, Rong-Rui
name: Liao, Qian
name: Zhai, Lu
name: You, Xue-Mei
name: Zuo, Yan-Li
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: Additional file 1: Figure S1. Mediating pathway of the association of BMI with stroke. Figure S2. Flowchart of the study population. Figure S3. Nonlinear association between body mass index and triglyceride-glucose. Table S1. Baseline characteristics between participants included and not included. Table S2. Baseline characteristics of the include participants and those without blood samples and incomplete information on body mass index and triglyceride-glucose index. Table S3. Association between body mass index and triglyceride-glucose index using multiple linear regression. Table S4. Incremental predictive value of BMI and TyG index beyond traditional risk factors. Table S5. E-values of triglyceride-glucose index and body mass index with stroke. Table S6. Decomposition of the total association between BMI and the risk of stroke into direct and indirect associations mediated by the TyG index stratified by age. Table S7. Decomposition of the total association between BMI and the risk of stroke into direct and indirect associations mediated by the TyG index stratified by gender. Table S8. Interactive effects of triglyceride-glucose index and body mass index on incident stroke stratified by age. Table S9. Interactive effects of triglyceride-glucose index and body mass index on incident stroke stratified by gender. Table S10. Joint associations of triglyceride-glucose index and body mass index with incident stroke stratified by age. Table S11. Joint associations of triglyceride-glucose index and body mass index with incident stroke stratified by gender. Table S12. Decomposition of the total association between BMI and the risk of stroke into direct and indirect associations mediated by the TyG index in subpopulations of 7956 participants with complete data. Table S13. Interactive effects of triglyceride-glucose index and body mass index on incident stroke in subpopulations of 7 956 participants with complete data. Table S14. Joint associations of triglyceride-glucose index and body mass index with incident stroke in subpopulations of 7 956 participants with complete data. Table S15. Association between body mass index and triglyceride-glucose index at Wave 3 using multiple linear regression. Table S16. Decomposition of the total association between BMI and the risk of stroke into direct and indirect associations mediated by the TyG index at Wave 3. Table S17. Interactive effects of triglyceride-glucose index at Wave 3 and body mass index on incident stroke. Table S18. Joint associations of triglyceride-glucose index at Wave 3 and body mass index with incident stroke. Table S19. Mediated effects by TyG on the associations of ALP BMI with risk of stroke using the four-way decomposition method.