cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: A randomized, controlled trial
Creators: name: Donnelly, Laura
name: Ried, Karin
name: Pase, Matthew
name: Travica, Nikolaj
name: Yoganathan, Jaesshanth
name: Scholey, Andrew
name: Macpherson, Helen
name: Kennedy, Greg
name: Sali, Avni
name: Pipingas, Andrew
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 520201
subject: Behavioural genetics
classificationCode: 520202
subject: Behavioural neuroscience
classificationCode: 520203
subject: Cognitive neuroscience
classificationCode: 520205
subject: Psychopharmacology
classificationCode: 520206
subject: Psychophysiology
classificationCode: 520207
subject: Social and affective neuroscience
classificationCode: 520301
subject: Clinical neuropsychology
classificationCode: 520401
subject: Cognition
classificationCode: 520403
subject: Learning, motivation and emotion

description: Cocoa supplementation has been associated with benefits to cardiovascular health. However, cocoa's effects on cognition are less clear. A randomized, placebo-controlled, double-blind clinical trial (n = 40, age M = 24.13 years, SD = 4.47 years) was conducted to investigate the effects of both acute (same-day) and sub-chronic (daily for four-weeks) 250 mg cocoa supplementation on mood and mental fatigue, cognitive performance and cardiovascular functioning in young, healthy adults. Assessment involved repeated 10-min cycles of the Cognitive Demand Battery (CDB) encompassing two serial subtraction tasks (Serial Threes and Sevens), a Rapid Visual Information Processing task, and a mental fatigue scale over the course of half an hour. The Swinburne University Computerized Cognitive Assessment Battery (SUCCAB) was also completed to evaluate cognition. Cardiovascular function included measuring both peripheral and central blood pressure and cerebral blood flow. At the acute time point, consumption of cocoa significantly improved self-reported mental fatigue and performance on the Serial Sevens task in cycle one of the CDB. No other significant effects were found. This trial was registered with the Australian and New Zealand Clinical Trial Registry (Trial ID: ACTRN12613000626763).
title: Metabolomic profiling reveals correlations between spermiogram parameters and the metabolites present in human spermatozoa and seminal plasma
title: Metabolomic profiling reveals correlations between spermiogram parameters and the metabolites present in human spermatozoa and seminal plasma
titleType: AlternativeTitle
Creators: name: Baumann, Sven
name: Engel, Kathrin M.
name: Rolle-Kampczyk, Ulrike
Publisher: name: My University
Year: 2019

description: In 50% of all infertility cases, the male is subfertile or infertile, however, the underlying mechanisms are often unknown. Even when assisted reproductive procedures such as in vitro fertilization and intracytoplasmic sperm injection are performed, the causes of male factor infertility frequently remain elusive. Since the overall activity of cells is closely linked to their metabolic capacity, we analyzed a panel of 180 metabolites in human sperm and seminal plasma and elucidated their associations with spermiogram parameters. Therefore, metabolites from a group of 20 healthy donors were investigated using a targeted LC-MS/MS approach. The correlation analyses of the amino acids, biogenic amines, acylcarnitines, lysophosphatidylcholines, phosphatidylcholines, sphingomyelins and sugars from sperm and seminal plasma with standard spermiogram parameters revealed that metabolites in sperm are closely related to sperm motility, whereas those in seminal plasma are closely related to sperm concentration and morphology. This study provides essential insights into the metabolome of human sperm and seminal plasma and its associations with sperm functions. This metabolomics technique could be a promising screening tool to detect the factors of male infertility in cases where the cause of infertility is unclear. Quelle: https://journals.plos.org
Patterns of acquisition in temporal connectives from a Reichenbachian perspective.
Creators: name: Sellar, Melanie J.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Language, Linguistics.

description: Since Clark's (1971) pioneering study, many experiments have been carried out which were designed to tap children's understanding of the temporal connectives before, after, when, and while. Many different patterns have been observed and different explanations have been invoked. In many instances, the reported results appear to be confounded by methodology, such as too great a demand on memory, or unnatural test materials. The present study investigates in particular the implications that a Reichenbachian theory of time may have on understanding children's acquisition of these connectives. This study examines a body of speech data obtained from the CHILDES database in order to determine whether there exist patterns that can shed light on the conflicts found in the experimental literature, with a particular emphasis on motivating Reichenbachian ideas. As well, the data is examined for patterns that suggest whether it is the semantics or the syntax of these connectives that drive their acquisition. All instances of before, after, when, and while were extracted from the speech of four children and their adult interlocutors. Two aspects of the data were focused on for analysis in this study: the frequency of the connectives; throughout the selected files and the preposing of temporal when-clauses. (Abstract shortened by UMI.)
Recent developments in photothermal therapy: a bibliometric and visual analysis
Creators: name: Guo, Runying
name: Zhang, Rongrong
name: Xin, Yuqi
name: Wang, Zhonghao
name: Xu, Zichen
name: Qiu, Jiaxuan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy
Virology

description: Photothermal therapy (PTT) has recently garnered significant attention as a prominent noninvasive treatment modality for a broad spectrum of diseases. Despite the increasing volume of scholarly output over the last 20 years, a holistic synthesis that delineates worldwide research trajectories remains elusive. We undertook a bibliometric analysis of the literature from 2004 to 2023, aiming to delineate the prevailing focal points and illuminate prospective research avenues. Research articles on PTT were retrieved from the Web of Science Core Collection. Using tools such as CiteSpace, VOSviewer, and Bibliometrix, we comprehensively analyzed and visualized 11,184 published academic PTT papers. China has the highest number of publications. Journals related to PTT are primarily comprised of interdisciplinary and comprehensive journals. Research associated with PTT has focused primarily on its antitumor properties. Current focal areas in this domain include the synergistic combination of PTT with photodynamic therapy, immunological mechanisms of PTT to enhance its therapeutic efficacy, integrated use of PTT with nanoenzyme catalysis, and the role of PTT in antimicrobial applications. This bibliometric analysis provides an initial comprehensive examination of the medical applications of PTT, offering insights into the global research landscape, key areas of interest, and emerging trends, thereby serving as a valuable reference for future studies in this field.
title: Fronto-limbic novelty processing in acute psychosis
title: disrupted relationship with memory performance and potential implications for delusions
titleType: Subtitle
Creators: name: Schott, Björn H.
name: Voss, Martin
name: Wagner, Benjamin
name: Wüstenberg, Torsten
name: Düzel, Emrah
name: Behr, Joachim
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: novelty
subject: hippocampus
subject: orbitofrontal cortex
subject: rostral anterior cingulate cortex
subject: ventral striatum
subject: schizophrenia
subject: psychosis
subject: fMRI
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Recent concepts have highlighted the role of the hippocampus and adjacent medial temporal lobe (MTL) in positive symptoms like delusions in schizophrenia. In healthy individuals, the MTL is critically involved in the detection and encoding of novel information. Here, we aimed to investigate whether dysfunctional novelty processing by the MTL might constitute a potential neural mechanism contributing to the pathophysiology of delusions, using functional magnetic resonance imaging (fMRI) in 16 unmedicated patients with paranoid schizophrenia and 20 age-matched healthy controls. All patients experienced positive symptoms at time of participation. Participants performed a visual target detection task with complex scene stimuli in which novel and familiar rare stimuli were presented randomly intermixed with a standard and a target picture. Presentation of novel relative to familiar images was associated with hippocampal activation in both patients and healthy controls, but only healthy controls showed a positive relationship between novelty- related hippocampal activation and recognition memory performance after 24 h. Patients, but not controls, showed a robust neural response in the orbitofrontal cortex (OFC) during presentation of novel stimuli. Functional connectivity analysis in the patients further revealed a novelty-related increase of functional connectivity of both the hippocampus and the OFC with the rostral anterior cingulate cortex (rACC) and the ventral striatum (VS). Notably, delusions correlated positively with the difference of the functional connectivity of the hippocampus vs. the OFC with the rACC. Taken together, our results suggest that alterations of fronto-limbic novelty processing may contribute to the pathophysiology of delusions in patients with acute psychosis.
title: A past, present, and future of Des Moines jazz
title: an ethnography of the Des Moines Community Jazz Center’s student jam session
titleType: Subtitle
Creators: name: Clowser, Ross
Publisher: name: University of Iowa
Year: 2022
Subjects: cultural transmission
jam session
jazz education
public abstract
Music Education

description: In Des Moines, Iowa, The Des Moines Community Jazz Center (CJC) has served as a hub for jazz musicians, educators, and students for over twenty years. Particularly through its monthly student jam sessions, the CJC helps facilitate community interaction, local learning practices, and cultural transmission, connecting multiple generations of musicians, volunteers, students, and educators in a community of practice. Though the organization began as an experimental model for jazz education nationwide, the CJC quickly adapted its practices and programming to reflect the needs of its participants and its community by focusing on student participation and personal growth. Through interviews, archival research, and ethnographic fieldwork, this research explores how the CJC, and its leaders facilitate cultural transmission and learning through student jam sessions that connect beginning and intermediate jazz students with local musicians and educators, constructing a model of local learning that dominated jazz education in the first half of the twentieth century. By bringing together students and professionals in a semi-structured and safe environment, the CJC builds a bridge between generations of musicians and sustains the local learning process. At the same time, while the sessions play a role in musical learning, in contrast to other models of jazz education, they do not emphasize quality of musical performance, instead focusing on student growth and individual development, frequently facilitated by ‘non-musicians’ or volunteers who are not invested in producing high performing students, but instead, well rounded individuals.
Proving properties of programs using automatically generated models.
Creators: name: Binard, Franck J. L.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Computer Science.

description: This thesis describes a method for automatically generating theories in a first order logic with arithmetic for the purpose of proving properties about the programs. We build the logic and define the syntactic model generation algorithm. The models can be used to prove a substantial class of properties that are true of the programs they are generated from. Here, a model is a set of formulas of the logic that are interpreted as mathematical function definitions. These functions describe the computation steps of the algorithm.
Surface grafting of electrospun fibers using ATRP and RAFT for the control of biointerfacial interactions
Creators: name: Ameringer, Thomas
name: Ercole, Francesca
name: Tsang, Kelly M.
name: Coad, Bryan R.
name: Hou, Xueliang
name: Rodda, Andrew
name: Nisbet, David R.
name: Thissen, Helmut
name: Evans, Richard A.
name: Meagher, Laurence
name: Forsythe, John S.
Publisher: name: Swinburne
Year: 2024

description: Background: The ability to present signalling molecules within a low fouling 3D environment that mimics the extracellular matrix is an important goal for a range of biomedical applications, both in vitro and in vivo. Cell responses can be triggered by non-specific protein interactions occurring on the surface of a biomaterial, which is an undesirable process when studying specific receptor-ligand interactions. It is therefore useful to present specific ligands of interest to cell surface receptors in a 3D environment that minimizes non-specific interactions with biomolecules, such as proteins. Method: In this study, surface-initiated atom transfer radical polymerization (SI-ATRP) of poly(ethylene glycol)-based monomers was carried out from the surface of electrospun fibers composed of a styrene/vinylbenzyl chloride copolymer. Surface initiated radical addition-fragmentation chain transfer (SI-RAFT) polymerisation was also carried out to generate bottle brush copolymer coatings consisting of poly(acrylic acid) and poly(acrylamide). These were grown from surface trithiocarbonate groups generated from the chloromethyl styrene moieties existing in the original synthesised polymer. XPS was used to characterise the surface composition of the fibers after grafting and after coupling with fluorine functional XPS labels. Results: Bottle brush type coatings were able to be produced by ATRP which consisted of poly(ethylene glycol) methacrylate and a terminal alkyne-functionalised monomer. The ATRP coatings showed reduced non-specific protein adsorption, as a result of effective PEG incorporation and pendant alkynes groups existing as part of the brushes allowed for further conjugation of via azide-alkyne Huisgen 1,3-dipolar cycloaddition. In the case of RAFT, carboxylic acid moieties were effectively coupled to an amine label via amide bond formation. In each case XPS analysis demonstrated that covalent immobilisation had effectively taken place. Conclusion: Overall, the studies presented an effective platform for the preparation of 3D scaffolds which contain effective conjugation sites for attachment of specific bioactive signals of interest, as well as actively reducing nonspecific protein interactions.
title: Perceptions of American health and safety professionals regarding the impact of North American Free Trade Agreements on health and safety
title: NAFTA and the USMCA
titleType: Subtitle
Creators: name: Eko, Kalyani E.
Publisher: name: University of Iowa
Year: 2023
Subjects: Bourdieu field theory
Global health and safety
International trade
NAFTA
Safety professionals
USMCA
International Relations

description: Background. Research has demonstrated that the labor provisions of the North American Free Trade Agreement (NAFTA) were not successful in protecting workers. However, there is limited information on the perspectives of health and safety professionals responsible for carrying out the health and safety provisions of NAFTA and its successor organization, the United States-Mexico-Canada Agreement (USMCA). Therefore, this research study seeks to understand the perceptions of American health and safety professionals (stakeholders) with respect to evolving health and safety legislation as NAFTA has transitioned to the USMCA.
description: Methods. To gather this information, a 47-question online survey based on an International Labour Organization questionnaire was administered to 347 self-identified American health and safety professionals. Using Pierre Bourdieu’s field theory of organizational sociology, each survey question was associated with one of four constructs that were defined for our study (free trade agreements, habitus, professional capital, and practice). Responses to our survey were evaluated using descriptive statistics, generalized structured component analysis (GSCA), and chi-square analysis.
description: Results. While our GSCA results suggest that NAFTA and the USMCA have positively influenced stakeholders’ habitus (estimate = 0.92, SE = 0.18, 95% CI = 0.49-0.99), they also indicate a general lack of knowledge and understanding among stakeholders regarding the health and safety provisions of North American free trade agreements.
description: Conclusions. The outcomes of this work can be used to inform policymakers who craft North American free trade agreements through an understanding of how the health and safety provisions of North American free trade agreements are diffused, understood, and practiced by American health and safety professionals in the field.
title: A Pilot RCT of Psychodynamic Group Art Therapy for Patients in Acute Psychotic Episodes
title: Feasibility, Impact on Symptoms and Mentalising Capacity
titleType: Subtitle
Creators: name: Montag, Christiane
name: Haase, Laura
name: Seidel, Dorothea
name: Bayerl, Martin
name: Gallinat, Jürgen
name: Herrmann, Uwe
name: Dannecker, Karin
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2014
Subjects: subject: 100 Philosophie und Psychologie::150 Psychologie

description: This pilot study aimed to evaluate the feasibility of an assessor-blind, randomised controlled trial of psychodynamic art therapy for the treatment of patients with schizophrenia, and to generate preliminary data on the efficacy of this intervention during acute psychotic episodes. Fifty-eight inpatients with DSM-diagnoses of schizophrenia were randomised to either 12 twice-weekly sessions of psychodynamic group art therapy plus treatment as usual or to standard treatment alone. Primary outcome criteria were positive and negative psychotic and depressive symptoms as well as global assessment of functioning. Secondary outcomes were mentalising function, estimated with the Reading the mind in the eyes test and the Levels of emotional awareness scale, self- efficacy, locus of control, quality of life and satisfaction with care. Assessments were made at baseline, at post-treatment and at 12 weeks' follow- up. At 12 weeks, 55% of patients randomised to art therapy, and 66% of patients receiving treatment as usual were examined. In the per-protocol sample, art therapy was associated with a significantly greater mean reduction of positive symptoms and improved psychosocial functioning at post-treatment and follow-up, and with a greater mean reduction of negative symptoms at follow-up compared to standard treatment. The significant reduction of positive symptoms at post-treatment was maintained in an attempted intention- to-treat analysis. There were no group differences regarding depressive symptoms. Of secondary outcome parameters, patients in the art therapy group showed a significant improvement in levels of emotional awareness, and particularly in their ability to reflect about others' emotional mental states. This is one of the first randomised controlled trials on psychodynamic group art therapy for patients with acute psychotic episodes receiving hospital treatment. Results prove the feasibility of trials on art therapy during acute psychotic episodes and justify further research to substantiate preliminary positive results regarding symptom reduction and the recovery of mentalising function.
Detection of cropland field parcels from Landsat imagery
Creators: name: Graesser, Jordan
name: Ramankutty, Navin
Publisher: name: The University of British Columbia
Year: 2019

description: A slowdown in global agricultural expansion, spurred by land limitations, improved technologies, and demand for specific crops has led to increased agricultural intensification. While agricultural expansion has been heavily scrutinized, less attention has been paid to changes within cropland systems. Here we present a method to detect individual cropland field parcels from temporal Landsat imagery to improve cropland estimates and better depict the scale of farming across South America. The methods consist of multi-spectral image edge extraction and multi-scale contrast limited adaptive histogram equalization (CLAHE) and adaptive thresholding using Landsat Surface Reflectance Climate Data Record (CDR) products. We tested our methods across a South American region with approximately 82% of the 2000/2001 total cropland area, using a Landsat time series composite with a January 1, 2000 to August 1, 2001 timeframe. A thematic accuracy assessment revealed an overall cropland f-score of 91%, while an object-based assessment of 5,480 fields showed low geometric errors. The results illustrate that Landsat time series can be used to accurately estimate cropland in South America, and the low geometric errors of the per-parcel estimates highlight the applicability of the proposed methods over a large area. Our approach offers a new technique of analyzing agricultural changes across a broad geographic scale. By using multi-temporal Landsat imagery with a semi-automatic field extraction approach, we can monitor within-agricultural changes at a high degree of accuracy, and advance our understanding of regional agricultural expansion and intensification dynamics across South America.
Access to digital content - time to reboot
Creators: name: Perrier, Jane
Publisher: name: Swinburne
Year: 2024

description: Online copyright enforcement impacts the Internet industry as a whole, including different types of rights holders, ISPs, other content providers, technology providers and users. All these parties should be engaged in the discussion, which in turn needs to be broadened to include how access to authorised digital content is being improved via distribution, monetisation and enforcement models that are better suited to emerging technologies and market expectations.
The feature interaction problem: Automatic filtering of incoherences and generation of validation test suites at the design stage.
Creators: name: Gorse, Nicolas.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Computer Science.

description: This thesis addresses the feature interaction problem in the research area of telephone systems design. We start with a review of this problem and present our definition of a feature and of a feature interaction. We enumerate and discuss some known approaches with respect to their strengths and limitations. We present our initial approach and propose some refinements in order to automate the detection of incoherences and derivation of validation scenarios at the design stage using predicate logic and Prolog. The identification of incoherences corresponding to potential feature interactions allows the designer to refine the requirements and to produce a better specification. A UCM model is derived from requirements. This model allows the designers to have a general point of view of the system and to detect design defaults. The construction of the UCM model is followed by the generation of a LOTOS specification. The derivation of validation test suites and their application against the specification permits to check whether or not the incoherences identified in the requirements lead to feature interactions. The results obtained over two case studies show that the application of this approach improves the design and validation of a specification.
Multivariate non-parametric quality control statistics.
Creators: name: Ghoudi, Kilani.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Engineering, System Science.

description: During the startup phase of a production process while statistics on the product quality are being collected it is useful to establish that the process is under control. Small samples $\{ n\sb{i}\} \sbsp{i=1}{q}$ are taken periodically for $q$ periods. We shall assume each measurement is bivariate. A process is under control or on-target if all the observations are deemed to be independent and identically distributed and moreover the distribution of each observation is a product distribution. This would be the case if each coordinate of an observation is a nominal value plus noise. Let $F\sp{i}$ represent the empirical distribution function of the $i\sp{-th}$ sample. Let $\overline {F}$ represent the empirical distribution function of all observations. Following Lehman (1951) we propose statistics of the form$${\sum\limits\sbsp{i = 1}{q}}\int\sbsp{-\infty}{\infty}\int\sbsp{-\infty}{\infty}(F\sp{i}(s,t) - \overline{F}(s)\overline{F}(t))\sp2 d\overline{F}(s,t)\eqno(1)$$The emphasis there, however, is on the case where $n\sb{i}\ \to\ \infty$ while $q$ stayed fixed. Here we study the following family of statistics$$S\sb{q}={\sum\limits\sbsp{i = 1}{q}}\int\sbsp{-\infty}{\infty}\int\sbsp{-\infty}{\infty}k\sb{q}(n, i, F\sp{i}(s,t),\overline{F}(s)\overline{F}(t))n\sb{i}dF\sp{i}(s,t)\eqno(2)$$in the above quality control situation, where $q\to\infty$ while $n\sb{i}$ stays fixed. (Abstract shortened by UMI.)
Sedimentology and tectonic implications of the Pointe la Nim and Campbellton formations, western Chaleur Bay, maritime Canada.
Creators: name: Gamba, Charle A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Geology.

description: The middle to late Emsian clastic succession of the western Chaleur Bay region comprises the newly defined Pointe la Nim Formation and the overlying Campbellton Formation. The type and orientations of the fluvial systems present in the succession lends insight into the larger scale basin configurations and the nature and timing of major allocyclic events. The succession documents a transition from synvolcanic to syntectonic fluvial sedimentation related to a transition from subduction related island arc volcanism to uplift and dissection of the volcanic arc during the early stages of the Acadian Orogeny. The middle Emsian Pointe la Nim Formation is composed of interbedded extrusive volcanics, pyroclastics, and a wide range of fluvial deposits which exhibit a southwestwards to northeastwards proximal to distal trend. The mid to late Emsian Campbellton Formation overlies the Pointe la Nim Formation with local discordance, and can be subdivided into four distinct members: the lacustrine Atholville Member and the fluvial Pointe a la Garde, Pointe a Bourdeau, and Restigouche Members. (Abstract shortened by UMI.)
Medical students’ preparedness for professional activities in early clerkships
Creators: name: Bosch, Josefin
name: Maaz, Asja
name: Hitzblech, Tanja
name: Holzhausen, Ylva
name: Peters, Harm
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background Sufficient preparedness is important for transitions to workplace participation and learning in clinical settings. This study aims to analyse medical students’ preparedness for early clerkships using a three-dimensional, socio-cognitive, theory-based model of preparedness anchored in specific professional activities and their supervision level. Methods Medical students from a competency-based undergraduate curriculum were surveyed about preparedness for 21 professional activities and level of perceived supervision during their early clerkships via an online questionnaire. Preparedness was operationalized by the three dimensions of confidence to carry out clerkship activities, being prepared through university teaching and coping with failure by seeking support. Factors influencing preparedness and perceived stress as outcomes were analysed through step-wise regression. Results Professional activities carried out by the students (n = 147; 19.0%) and their supervision levels varied. While most students reported high confidence to perform the tasks, the activity-specific analysis revealed important gaps in preparation through university teaching. Students regularly searched for support in case of difficulty. One quarter of the variance of each preparedness dimension was explained by self-efficacy, supervision quality, amount of prior clerkship experience and nature of professional activities. Preparedness contributed to predicting perceived stress. Conclusions The applied three-dimensional concept of preparedness and the task-specific approach provided a detailed and meaningful view on medical students’ workplace participation and experiences in early clerkships.
Weiterentwicklung der biologischen Bewertungsverfahren zur EG-Wasserrahmenrichtlinie (EG-WRRL) unter besonderer Berücksichtigung der großen Flüsse
Creators: name: (:Unkn) Unknown
Publisher: name: Umweltbundesamt
Year: 2020
Subjects: subject: Fließgewässer
subject: Perlodes
subject: PhytoFluss
subject: Phylib
subject: Makrozoobenthos
subject: Phytoplankton
subject: Diatomeen
subject: Phytobenthos
subject: POD
subject: Taxaliste
subject: Wasser

description: Zur Umsetzung der EG-Wasserrahmenrichtline wurden Bewertungsverfahren entwickelt, deren Ziel es ist, die Fließgewässer in Deutschland anhand biologischer Qualitätskomponenten ökologisch zu bewerten. Im Projekt „Weiterentwicklung der biologischen Bewertungsverfahren zur EG-⁠Wasserrahmenrichtlinie⁠ (EG-WRRL) unter besonderer Berücksichtigung der großen Flüsse“ wurden die in den vergangenen Jahren gesammelten Erfahrungen und Verbesserungsvorschläge der Anwender bearbeitet. Das Ziel bestand in der Verbesserung  der  Genauigkeit und Zuverlässigkeit der biologischen Bewertungsverfahren. Der Fokus des Projekts lag auf der Weiterentwicklung der biologischen Bewertungsverfahren: „Perlodes“, „PhytoFluss“ und „Phylib“. Bei letztgenanntem Verfahren „Phylib“ waren die Weiterentwicklungen auf die Teilkomponenten Diatomeen und Phytobenthos ohne Diatomeen (PoD) beschränkt.
Analysis of novel high-performance switch architectures for broadband-ISDN.
Creators: name: Gupta, Anil K.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Engineering, Electronics and Electrical.

description: In this thesis, we present an analysis of three novel switch architectures for Broadband-ISDN using the Asynchronous Transfer Mode (ATM). Our focus is on high-performance switch architectures, which have low to medium hardware complexity. The first switch architecture presented is a speed-up switch with input and output buffers, where a back-pressure mechanism is applied to avoid packet loss at the output buffers. We examine the maximum throughput, mean delay and packet loss rate at the input buffers of this speed-up switch. The switch with a speed-up of 3, and 20 buffers at each output port can achieve a maximum throughput of 90% or more. These results are of a great practical value since a switch with high speed-up is difficult to realize. A simple implementation of the switch is also presented. The second switch architecture, called Limited Intermediate Buffer (LIB) switch, is based on a crossbar switch fabric. A buffer to store a single packet is provided at each crosspoint of this switch. In addition to this, buffers are provided at the input ports to reduce the packet loss. We propose a new scheduling policy called head-of-line priority selection, which reduces the head-of-line blocking and thus improves the performance of the LIB switch substantially. A 16 x 16 switch under uniform random traffic can achieve a throughput of 87.5%. A three-stage interconnection network consisting of symmetric and asymmetric LIB switch modules is also presented. The simulation results of the interconnection network prove the efficacy of the LIB switch architecture and the proposed head-of-line priority selection scheme. Finally, the handling of delay and loss sensitive traffic in ATM networks is discussed. To keep the protocols simple at the ATM layer, we suggest that the handling of these priorities should be de-linked. The performance of two classes of delay-sensitive traffic in an input buffered nonblocking switch architecture is analyzed. The result of the analysis under two different non-preemptive priority schemes suggests that, to reduce the hardware complexity, the packets should not be distinguished based on their priority within the switch fabric. To overcome the throughput limitation of the input buffered switch, a dual plane switch architecture is presented, where each plane is a nonblocking switch with input buffers.
Best practices for comparing optimization algorithms
Creators: name: Beiranvand, Vahid
name: Hare, Warren
name: Lucet, Yves
Publisher: name: Springer
Year: 2019

description: Comparing, or benchmarking, of optimization algorithms is a complicated task that involves many subtle considerations to yield a fair and unbiased evaluation. In this paper, we systematically review the benchmarking process of optimization algorithms, and discuss the challenges of fair comparison. We provide suggestions for each step of the comparison process and highlight the pitfalls to avoid when evaluating the performance of optimization algorithms. We also discuss various methods of reporting the benchmarking results. Finally, some suggestions for future research are presented to improve the current benchmarking process.
The mediating role of task orientation in the relation between parenting practices and children's cognitive performance.
Creators: name: Rinholm, Joanne.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Education, Educational Psychology.

description: The present study was designed to clarify the relations between parenting practices and cognitive performance in school-aged children. Particular attention was directed toward the identification of gender differences in the pattern of relations among variables and toward investigating a model of how parenting practices may influence children's cognitive performance. The model postulated that parenting practices affect children's task orientation (i.e., mastery behaviors and impulse control), which in turn affects their cognitive performance. Using path analysis, the model was assessed in a sample of 63 female and 62 male Grade 6 children. The measure of cognitive performance was academic grades, and the possible confounding influence of cognitive ability upon academic grades was controlled. As expected, maternal encouragement of independence predicted both boys' and girls' academic performance, with mastery behaviors mediating the relation in the female sample. Paternal nurturance also predicted girls' academic performance, with impulse control mediating this association. The remaining findings of the study provided support for individual components of the model. With respect to the relations between parenting practices and task orientation, maternal nurturance predicted both higher mastery behaviors and impulse control in the female sample. For girls, paternal restrictive control predicted lower impulse control, whereas maternal restrictive control predicted higher impulse control. For boys, both maternal and paternal nurturance predicted higher impulse control. In both the male and female samples, the expected associations between academic performance and both mastery behaviors and impulse control were obtained. The implications of the results and suggestions for future research were discussed.
Morphological fractions of galaxies in WINGS clusters: revisiting the morphology-density paradigm
Creators: name: Fasano, G.
name: Poggianti, B. M.
name: Bettoni, D.
name: D'Onofrio, M.
name: Dressler, A.
name: Vulcani, B.
name: Moretti, A.
name: Gullieuszik, M.
name: Fritz, J.
name: Omizzolo, A.
name: Cava, A.
name: Couch, Warrick
name: Ramella, M.
name: Biviano, A.
Publisher: name: Swinburne
Year: 2024

description: We present the Morphology-Density and Morphology-Radius relations (T-Sigma and T-R, respectively) obtained from the WINGS database of galaxies in nearby clusters. Aiming to achieve the best statistics, we exploit the whole sample of galaxies brighter than MV=-19.5 (5,504 objects), stacking up the 76 clusters of the WINGS survey altogether. Using this global cluster sample, we find that the T-Sigma relation holds only in the inner cluster regions (R<1/3xR200), while the T-R relation keeps almost unchanged over the whole range of local density. A couple of tests and two sets of numerical simulations support the robustness of these results against the effects of the limited cluster area coverage of the WINGS imaging. The above mentioned results hold for all cluster masses (X-ray luminosity and velocity dispersion) and all galaxy stellar masses (M). The strength of the T-Sigma relation (where present) increases with increasing M, while this effect is not found for the T-R relation. Noticeably, the absence/presence of subclustering determines the presence/absence of the T-Sigma relation outside the inner cluster regions, leading us to the general conclusion that the link between morphology and local density is preserved just in dynamically evolved regions. We hypothesize that some mechanism of morphological broadening/redistribution operates in the intermediate/outer regions of substructured (non relaxed) clusters, producing a strong weakening of the T-Sigma relation.
Mutations in the Genes for Interphotoreceptor Matrix Proteoglycans, IMPG1 and IMPG2, in Patients with Vitelliform Macular Lesions
Creators: name: Brandl, Caroline
name: Schulz, Heidi L.
name: Issa, Peter Charbel
name: Birtel, Johannes
name: Bergholz, Richard
name: Lange, Clemens
name: Dahlke, Claudia
name: Zobor, Ditta
name: Weber, Bernhard H. F.
name: Stöhr, Heidi
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: vitelliform macular dystrophy
subject: IMPG1
subject: IMPG2
subject: interphotoreceptor matrix
subject: optical coherence tomography
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: A significant portion of patients diagnosed with vitelliform macular dystrophy (VMD) do not carry causative mutations in the classic VMD genes BEST1 or PRPH2. We therefore performed a mutational screen in a cohort of 106 BEST1/PRPH2-negative VMD patients in two genes encoding secreted interphotoreceptor matrix proteoglycans-1 and -2 (IMPG1 and IMPG2). We identified two novel mutations in IMPG1 in two simplex VMD cases with disease onset in their early childhood, a heterozygous p.(Leu238Pro) missense mutation and a homozygous c.807 + 5G > A splice site mutation. The latter induced partial skipping of exon 7 of IMPG1 in an in vitro splicing assay. Furthermore, we found heterozygous mutations including three stop [p.(Glu226*), p.(Ser522*), p.(Gln856*)] and five missense mutations [p.(Ala243Pro), p.(Gly1008Asp), p.(Phe1016Ser), p.(Tyr1042Cys), p.(Cys1077Phe)] in the IMPG2 gene, one of them, p.(Cys1077Phe), previously associated with VMD. Asymptomatic carriers of the p.(Ala243Pro) and p.(Cys1077Phe) mutations show subtle foveal irregularities that could characterize a subclinical stage of disease. Taken together, our results provide further evidence for an involvement of dominant and recessive mutations in IMPG1 and IMPG2 in VMD pathology. There is a remarkable similarity in the clinical appearance of mutation carriers, presenting with bilateral, central, dome-shaped foveal accumulation of yellowish material with preserved integrity of the retinal pigment epithelium (RPE). Clinical symptoms tend to be more severe for IMPG1 mutations.
The role of CFTR in the biliary tract
Creators: name: Zarei, Keyan
Publisher: name: University of Iowa
Year: 2023
Subjects: public abstract

description: Cystic fibrosis (CF) is a genetic disease that leads to abnormal function of an anion channel known as the cystic fibrosis transmembrane conductance regulator (CFTR). In the past, CF was a pediatric disease; the development of therapies has allowed people with CF to live longer. CFTR is expressed in many organs. Tissues that highly express CFTR are the bile ducts in the liver and the gallbladder; together, these tissues are referred to as the biliary tract. Disease in the liver and gallbladder is the third leading cause of death for people with CF. In this dissertation, we sought to better understand CF disease in the biliary tract through two methods: 1) using a pig model of CF that closely resemble human disease; 2) using organoids, a cell culture technique that creates a representation of an organ in a dish. Using these techniques, we found that CFTR may be important for fluid secretion and clearance in the biliary tract.
Visualization of the ε-subdifferential of piecewise linear-quadratic functions
Creators: name: Bajaj, Anuj
name: Hare, Warren
name: Lucet, Yves
Publisher: name: Springer
Year: 2019

description: Computing explicitly the ε-subdifferential of a proper function amounts to computing the level set of a convex function namely the conjugate minus a linear function. The resulting theoretical algorithm is applied to the the class of (convex univariate) piecewise linear–quadratic functions for which existing numerical libraries allow practical computations. We visualize the results in a primal, dual, and subdifferential views through several numerical examples. We also provide a visualization of the Brøndsted–Rockafellar theorem.
Queer Christina of Sweden: How Evolving Accounts of a Long Dead Queen’s Sexuality Reflect More Upon Us Than Her
Creators: name: Klein, Grace
Publisher: name: Stanford Digital Repository
Year: 2024
Subjects: College students' writings, historiography, LGBTQ+, rhetoric, Queen Christina, biography, narrative

description: This essay won or received an honorable mention for The Boothe Prize for excellence in first-year writing. The Boothe Prize recognizes and rewards outstanding expository and argumentative writing by undergraduate students in first-year classes that satisfy the WR 1 requirement. In each award-winning essay, student writers demonstrate clarity of argument, excellent integration of research-based evidence, and compelling prose style.
This essay details the evolving interpretations of a 17th-century queen whose personal eccentricities have fueled a debate about whether she was a lesbian. Grace Klein argues that providing a label for Christina’s sexuality is not all that important, but that the ways in which the discourse around her has unfolded must be interrogated for the light they shed on how LGBTQ+ perspectives have shifted across the centuries.
CONNECTION between the CIRCUMGALACTIC MEDIUM and the INTERSTELLAR MEDIUM of GALAXIES: RESULTS from the COS-GASS SURVEY
Creators: name: Borthakur, Sanchayeeta
name: Heckman, Timothy
name: Tumlinson, Jason
name: Bordoloi, Rongmon
name: Thom, Christopher
name: Catinella, Barbara
name: Schiminovich, David
name: Davé, Romeel
name: Kauffmann, Guinevere
name: Moran, Sean M.
name: Saintonge, Amelie
Publisher: name: Swinburne
Year: 2024

description: We present a study exploring the nature and properties of the circumgalactic medium (CGM) and its connection to the atomic gas content in the interstellar medium (ISM) of galaxies as traced by the H i 21 cm line. Our sample includes 45 low-z (0.026–0.049) galaxies from the GALEX Arecibo SDSS Survey (Galaxy Evolution Explorer/Arecibo/Sloan Digital Sky Survey). Their CGM was probed via absorption in the spectra of background quasi-stellar objects at impact parameters of 63–231 kpc. The spectra were obtained with the Cosmic Origins Spectrograph aboard the Hubble Space Telescope. We detected neutral hydrogen (Lyα absorption lines) in the CGM of 92% of the galaxies. We find that the radial profile of the CGM as traced by the Lyα equivalent width can be fit as an exponential with a scale length of roughly the virial radius of the dark matter halo. We found no correlation between the orientation of the sightline relative to the galaxy's major axis and the Lyα equivalent width. The velocity spread of the circumgalactic gas is consistent with that seen in the atomic gas in the ISM. We find a strong correlation (99.8% confidence) between the gas fraction (M(H i)/Msstarf) and the impact-parameter-corrected Lyα equivalent width. This is stronger than the analogous correlation between corrected Lyα equivalent width and specific star formation rate (SFR)/Msstarf (97.5% confidence). These results imply a physical connection between the H i disk and the CGM, which is on scales an order of magnitude larger. This is consistent with the picture in which the H i disk is nourished by accretion of gas from the CGM.
A non-interventional, observational study of a fixed combination of pepsin and amino acid hydrochloride in patients with functional dyspepsia
Creators: name: Forssmann, Kristin
name: Meier, Larissa
name: Uehleke, Bernhard
name: Breuer, Cornelia
name: Stange, Rainer
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Functional dyspepsia
subject: Observational trial
subject: Non-interventional trial
subject: Natural remedy
subject: Enzyme therapy
subject: Pepsin
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Functional dyspepsia (FD) is a gastrointestinal disorder characterized by recurrent and diverse symptoms and pathophysiology that remains unexplained following routine clinical investigation. Enzynorm®f is a pharmaceutical preparation comprising fixed amounts of pepsin of biological origin and organically bound acid in the form of amino acid hydrochloride. It is traditionally used as a mild agent to support gastric function and to stimulate the stomach’s proteolytic activities in FD.