cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Fabrication of crosslinked starch microspheres via water-in-water Pickering emulsion and their application in controlled release of Vitamin C
Creators: name: Liu, Chengbo
name: Li, Jian
name: Wang, Chenyi
name: Ren, Qiang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Green technology for the fabrication of bio-degradable microspheres is exciting and needed. In this study, a new water-in-water Pickering emulsion green technology is proposed for the fabrication of the crosslinked starch microspheres with sodium tripolyphosphate as the crosslinker, polyethylene glycol aqueous solution as the continuous phase (PEG phase) and starch aqueous solution as the dispersed phase (starch phase). The factors that affect the morphology and particle sizes of cross-linked starch microspheres are investigated by laser scanning confocal microscope (LCM) and laser particle size analyzer. The results reveal that the particle sizes of crosslinked starch microspheres are increasing with increased starch concentration. The particle sizes of crosslinked starch microspheres show a first increase and then decrease trend with the increase of the concentration of PEG 20,000 in the PEG phase. The hydrophobic nano silica is used as an emulsifier to form water-in-water Pickering emulsion and shows an obvious effect on the morphology of starch microspheres. When the starch concentration is 20.00 wt%, PEG 20000 concentration is 32.56 wt%, the ratio of starch to PEG phase is 0.20 and the amount of silica is 5.00 wt% of starch, starch microspheres with regular shapes are obtained with the size of about 32.30 ± 0.22 µm. The fabricated cross-linked starch microspheres are non-crystalline and show good water and oil absorption performances. The application of fabricated crosslinked starch microspheres in the adsorption and release of Vitamin C is conducted. The maximum adsorption capacity of crosslinked starch microspheres for Vitamin C reaches 309.9 mg/g. Starch microspheres show a controlled release of Vitamin C in water. This study indicated that crosslinked starch microspheres can be fabricated through a green water-in-water Pickering emulsion technology and may find potential applications in degradable controlled-release microspheres.
Syntormon bulgariensis Negrobov & Kechev 2012
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon bulgariensis

description: 248. Syntormon bulgariensis Negrobov & Kechev, 2012 (Sympycninae)
BG: Pamporovo (Negrobov & Kechev 2012).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 463, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Venetoclax is effective for chronic myelomonocytic leukemia blastic transformation with RUNX1 mutation
Creators: name: Kashima, Emiko
name: Sugimoto, Yuka
name: Nagaharu, Keiki
name: Ohya, Eiko
name: Ikejiri, Makoto
name: Watanabe, Yasuyuki
name: Kageyama, Shinichi
name: Oka, Koji
name: Tawara, Isao
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Background: Chronic myelomonocytic leukemia is a clonal hematological disorder with an inherent risk of transformation to acute myeloid leukemia. Recently, there has been exponential discovery of molecular abnormalities in patients with chronic myelomonocytic leukemia. Some of these mutations independently contribute to a higher risk of transformation and result in inferior overall survival. Treatment strategies for patients undergoing blastic transformation in chronic myelomonocytic leukemia, especially after progressing on hypomethylating agents, are currently limited. Case presentation: We present a case of a 70-year-old male patient with chronic myelomonocytic leukemia blastic transformation with RUNX1 mutation following azacitidine monotherapy. Notably, he achieved hematological complete remission after the first course of venetoclax plus azacitidine, leading to the disappearance of RUNX1 mutation. We performed serial assessments of molecular analysis by next generation sequencing throughout his clinical course. Conclusion: The presence of RUNX1 mutation is associated with higher response rates to venetoclax-based combination therapies in chronic myelomonocytic leukemia with blastic transformation. Our findings suggest that even after azacitidine monotherapy, venetoclax plus azacitidine is effective in targeting leukemic clones harboring RUNX1 mutations. Furthermore, we emphasize the significance of molecular analysis, including next-generation sequencing, in providing insights into the detailed dynamics of clonal evolution and guiding treatment decisions.
REE induced defects in minerals : a spectroscopic study
Creators: name: Horsburgh, Nicola Jane
Publisher: name: University of St Andrews
Year: 2020
Subjects: subject: TN490.A2H7
subject: Rare earth metals
subject: Minerals

description: This thesis examines the luminescence and mineral physics of Rare Earth Element (REE) bearing minerals as a precursor to developing smart sorting tools for critical metals used in low-carbon technologies. I characterise luminescence responses of complex zirconosilicates; eudialyte (Na₁₅Ca₆(Fe²⁺,Mn²⁺)₃Zr₃[Si₂₅O₇₃](O,OH,H₂O)₃(OH,Cl)₂), wöhlerite (NaCa₂(Zr,Nb)(Si₂O₇)(O,OH,F)₂) and catapleiite (Na₂Zr(Si₃O₉) · 2H2₂O). Fluorite was included as it is commonly associated with REE ores and displays strong REE luminescence. Its behaviour provides key insights into REE substitution into ionic minerals. X-ray Excited Optical Luminescence (XEOL) and Thermoluminescence (TL) measurements were taken from 20 to 673 K. Fluorite responses result from a balance of intrinsic luminescence and REE substituents and evidence for REE and defect coupling. TL indicates the presence of electron traps and the coupling of these traps to lanthanide emissions, and it shows that the defect and the lanthanide are clustered in physical space. The absence of changes in TL for different lanthanides shows that energy is passed efficiently between rare earths, indicating that the REE are clustered. The zirconosilicates all show increased intensity in XEOL response below 150 K. Cryogenic emissions are interpreted as originating from the host mineral. There are 3 shared features: UV (~280 nm) paramagnetic oxygen or oxygen vacancy; blue (440 nm) Al-O⁻-Al /Ti centres; and REE. Wöhlerite and eudialyte show Fe³⁺ band (~708 nm) and wöhlerite displays broad emission attributed to Mn²⁺. Eudialyte shows two additional responses; UV (~320 nm) tentatively assigned to Na migration and UV/blue (~400 nm) potentially associated with charge balances associated with the coupled substitution of Al³⁺. Eudialyte shows little emission at room temperature, this is attributed to quenching from Fe²⁺. Emission from eudialyte above room temperature is attributed to alteration minerals such as catapleiite and potentially to inclusions of luminescent primary mineral phases. I demonstrate that smart sorting could be a valuable beneficiation tool for REE minerals.
Syntormon denticulatum Sympycninae
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon denticulatum

description: 249. Syntormon denticulatum (Zetterstedt, 1843) (Sympycninae)
BA: Vlašić (Strobl 1900); BG: Gorno Belevo village, Omurovska River, The Upper Thracian Plain (Kechev et al. 2014); Kayaliika river near Varbitsa village (Kechev 2014); Basha near Chirpan (Kechev & Ivanova 2015a); Rila Mts. (Hubenov 2016, 2017); GR: Trikala, Orthovounion (Grichanov 2009); RS: Crni Vrh, Stara Planina Mts. (Grichanov 2016).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 463, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Delirium associated with the use of macrolide antibiotics: a review
Creators: name: Pejčić, Ana V.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: This review aimed to explore and summarise available cases of delirium suspected to be associated with the use of macrolide antibiotics reported in the literature and the United States Food and Drug Administration’s Adverse Event Reporting System (FAERS) database. Electronic searches of the literature were conducted in four online databases: PubMed/MEDLINE, Scopus, Web of Science and Serbian Citation Index (SCIndeks). A search of FAERS database was also conducted to supplement the findings of the literature search. Descriptive statistics, narrative summation and tabulation of the extracted data were made. Cases of delirium which satisfied inclusion criteria were found for clarithromycin, azithromycin, erythromycin and telithromycin. Delirium was described in patients of various age groups, including children. Drug-drug interactions may have contributed to its occurrence in some of the cases. Average time to onset of delirium was 2.5 days for azithromycin and 3.3 days for clarithromycin. Considering that these drugs may be a possible cause of delirium, clinicians should be aware that timely recognition of this possible side effect can lead to earlier discontinuation of the culprit drug, reduce time spent in a delirious state and improve patients’ outcomes.KEY POINTSCases of delirium which satisfied inclusion criteria were found for clarithromycin, azithromycin, erythromycin and telithromycin.Cases of delirium were described in patients of various age groups, including children.Drug-drug interactions may have contributed to the occurrence of delirium in some of the cases.Time to onset of delirium ranged from 2 to 3.5 days (mean: 2.5 days) for azithromycin and from 1 to 7 days (mean: 3.3 days) for clarithromycin.Cessation of the macrolide antibiotic seems to be the best management strategy, although some of the patients may, in addition, require antipsychotics. Cases of delirium which satisfied inclusion criteria were found for clarithromycin, azithromycin, erythromycin and telithromycin. Cases of delirium were described in patients of various age groups, including children. Drug-drug interactions may have contributed to the occurrence of delirium in some of the cases. Time to onset of delirium ranged from 2 to 3.5 days (mean: 2.5 days) for azithromycin and from 1 to 7 days (mean: 3.3 days) for clarithromycin. Cessation of the macrolide antibiotic seems to be the best management strategy, although some of the patients may, in addition, require antipsychotics.
Neutrophil count and reduced risk of venous thromboembolism: a Mendelian randomization study
Creators: name: Zhao, Jiaojie
name: Zhang, Weixun
name: Wei, Houyi
name: Liu, Siyang
name: Cui, Songping
name: Chen, Shuo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy
subject: Hematology

description: Venous thromboembolism (VTE) has a close relationship with the immune system, particularly neutrophils. This study aimed to investigate the association between blood cell traits and VTE using Mendelian randomization (MR). In this study, we discovered specific genetic variants associated with blood cell traits through genome-wide association studies (GWAS) conducted on 173,480 individuals of European ancestry. Additionally, we gathered summary level data on VTE from FinnGen consortium involving 377,277 individuals. To explore the connections between blood cell traits and VTE, we employed various methods, including inverse variance weighted (IVW), Mendelian Randomization-Egger (MR-Egger), weighted median, and weighted mode for comprehensive analysis, as well as Multivariable MR (MVMR) to adjust for potential confounders. The results of this study indicated that an elevated neutrophil count was a protective factor against VTE (odds ratio [OR] = 0.80, 95% confidence interval [CI] = 0.70–0.91, p = 1.19 × 10−3). The results were confirmed to be reliable through sensitivity analysis, which demonstrated the absence of horizontal pleiotropy, and random effects model of IVW eliminates the impact of heterogeneity. MVMR confirmed a stable causal link between neutrophil count and VTE (OR = 0.83, CI = 0.76–0.91, p = 9.97 × 10−5) after adjusting for type 2 diabetes and obesity. According to our MR study, we found evidence suggesting that higher neutrophil count linked to a lower risk of VTE. These findings may provide potential therapeutic targets for the prevention and treatment of VTE.
Prevalence, trends, and outcomes of hematological malignancies in patients with hemophagocytic lymphohistiocytosis
Creators: name: Zhang, Qi
name: Yu, Qiuyan
name: Chen, Qian
name: Dong, Hongjing
name: Fang, Min
name: Liu, Na
name: Li, Wen
name: Wang, Hui
name: Zhao, Nan
name: Zhu, Xunxun
name: Zhang, Kui
name: Zhou, Chi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Virology

description: Hemophagocytic lymphohistiocytosis (HLH) is an acute, rapidly progressive systemic inflammatory disorder that often occurs secondary to hematological malignancies among other conditions in adults. Although the annual incidence of HLH is increasing, detailed epidemiological knowledge of HLH is still limited, especially in patients with hematological malignancies. To analyze the impact of hematological malignancies on the epidemiology and outcomes of HLH. Data from the National Readmission Database (NRD) from 2011 to 2020 were analyzed to explore the epidemiological trends and in-hospital outcomes of HLH patients, particularly those with hematological malignancies. Our analysis included 7579 HLH hospitalizations, with hematological malignancies implicated in 24.01% of cases. Our findings reveal a steady increase in HLH diagnoses from 145 cases in 2011 to 1848 in 2020, with the proportion linked to hematological malignancies remaining consistent. Patients with hematological malignancies-associated HLH exhibited higher rates of in-hospital mortality (31.6%) than those without (14.4%), and a higher 30-day readmission rate, underscoring a critical need for early detection and treatment revision. Despite the increasing awareness and diagnosis of HLH, the prognosis of patients with HLH associated with hematological malignancies remains poor, highlighting the urgent need for improved management strategies and therapeutic interventions.
Syntormon dobrogicus Parent 1985
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon dobrogicus

description: 250. Syntormon dobrogicus Parent, 1985 (Sympycninae)
RO-DO: Babadag, Dobroja Plateau (Pârvu 1985, 1989; Skolka 2003).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Additional file 1 of Students’ and junior doctors’ perspectives on radiology education in medical school: a qualitative study in the Netherlands
Creators: name: Harthoorn, Frederike S.
name: Scharenborg, Sascha W. J.
name: Brink, Monique
name: Peters-Bax, Liesbeth
name: Henssen, Dylan J. H. A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplementary Material 1
THE ADVANTAGES OF USING TECHNICAL MEANS IN INTRODUCING NATURE
Creators: name: Abdullayeva, Mekhribon
name: Matkarimova, Laylo
name: Sultanova, Bibimariyam
name: Akalaeva, Alfiya
Publisher: name: Zenodo
Year: 2024

description: in this article, the advantages of using technical means in introducing Nature. Introducing long-term seasonal changes in nature. opinions are expressed
Syntormon filiger Verrall 1912
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon filiger

description: 251. Syntormon filiger Verrall, 1912 (Sympycninae)
BG: Atanasovsko Lake near Burgas (Beschovski 1971); Omurovska River near Partizanin village (Kechev et al. 2014).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Additional file 1 of Effects of extracorporeal CO2 removal on gas exchange and ventilator settings: a systematic review and meta-analysis
Creators: name: Stommel, Alexandra-Maria
name: Herkner, Harald
name: Kienbacher, Calvin Lukas
name: Wildner, Brigitte
name: Hermann, Alexander
name: Staudinger, Thomas
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Additional file 1. Additional File A. PRISMA 2020 checklist. Additional File B. Criteria for considering studies for this review. Additional File C. Search strategy. Additional Table S1. Studies. Additional Table S2. Devices designed for ECCO2R and their basic specifications. Additional Table S3. Available data from included studies. Additional Table S4. Adverse Events from observational studies. Additional Figure S1: Risk of bias assessment (Robins-I tool). Additional Figure S2 a, and b: Change of (a) PaCO2, mmHg and (b) pH within 24 hours after initiating ECCO2R (all studies). Additional Figure S3 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2O within 24 hours after initiating ECCO2R (all studies). Additional Figure S4 a, b, and c: Change of (a) plateau pressure, cmH2O, (b) tidal volume, mL, and (c) respiratory rate, breaths/min within 24 hours after initiating ECCO2R (all studies). Additional Figure S5 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2Owithin 24 hours after initiating ECCO2R (diagnoses subgroups). Additional Figure S6 a, and b: Change of (a) PaCO2, mmHg (a) and (b) PaO2/FiO2 ratio, mmHg within 24 hours after initiating ECCO2R according to diagnosis and extraction. Additional Figure S7 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2O within 24 hours after initiating ECCO2R (lower extraction and higher extraction subgroups). Additional Figure S8 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2O within 24 hours after initiating ECCO2R according to diagnosis and extraction. Additional Figure S9 a, and b: Change of (a) plateau pressure, cmH2O and (b) tidal volume, mL within 24 hours after initiating ECCO2R (lower extraction and higher extraction subgroups). Additional Figure S10 a, b, and c: Change of (a) plateau pressure, cmH2O, (b) tidal volume, mL, and (c) respiratory rate, breaths/min within 24 hours after initiating ECCO2R according to diagnosis and extraction. Additional Figure S11 a-g: (a) PaCO2, mmHg, (b) pH, (c) PaO2/FiO2 ratio, mmHg and (d) PEEP, cmH2O, (e) plateau pressure, cmH2O, (f) tidal volume, mL and (g) respiratory rate, breaths/min according to risk of bias.
title: Analytic semigroups generated by Dirichlet-to-Neumann operators on manifolds
Creators: name: Binz, Tim
Publisher: name: Springer
Year: 2024

description: We consider the Dirichlet-to-Neumann operator associated to a strictly elliptic operator on the space C(∂M) of continuous functions on the boundary ∂M of a compact manifold M with boundary. We prove that it generates an analytic semigroup of angle π/2, generalizing and improving a result of Escher with a new proof. Combined with the abstract theory of operators with Wentzell boundary conditions developed by Engel and the author, this yields that the corresponding strictly elliptic operator with Wentzell boundary conditions generates a compact and analytic semigroups of angle π/2 on the space C(M).
ROBOTS CONTROL TECHNOLOGY USING THE ROBOTREK PLATFORM
Creators: name: Ochilov, M.R.
name: Ochilova, S.R.
name: Buriyev, B.B.
Publisher: name: Zenodo
Year: 2025

description: Analyzing the trends in the development of robotics today, one can imagine a future in which robots will become indispensable assistants in people's daily lives. Perhaps humanity is on the verge of a new era when personal computers will leave the desk and allow us to see, hear, touch and even manipulate objects from a distance. The technology of controlling the movement of robots was analyzed by installing sensors and motion mechanisms used to control robots using the Robotrek platform.
Real-world long-term safety and effectiveness of turoctocog alfa in the treatment of haemophilia A in Japan: results from a multicentre, non-interventional, post-marketing study
Creators: name: Nagao, Azusa
name: Deguchi, Ayumi
name: Nogami, Keiji
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: To assess the safety and effectiveness of turoctocog alfa in previously treated patients (PTPs) and previously untreated patients (PUPs) with haemophilia A in a real-world setting in Japan. This multicentre, non-interventional, post-marketing study recruited patients with haemophilia A who initiated treatment with turoctocog alfa from 18 sites (08/2014-12/2018). The primary endpoint was adverse events (AEs) during the 2-year study period. The safety and effectiveness analysis set included 39 patients. In total, 13 (33.3%) patients reported ≥1 AE; incidence rate was 60.4 events/100 patient-years of exposure (PYE). Treatment was withdrawn in two cases: pruritus in a PTP and factor VIII inhibitor development in a PUP. Inhibitor development occurred in 2.6% of all patients, with an incidence rate of 3.8 events/100 PYE. The rate of inhibitor development was 0%, 25% and 20% in PTPs, PUPs and PUPs with severe type, respectively. The haemostatic success rate was 91.4% for 383 bleeding episodes and 85.7% for 14 surgeries. The negative binomial annualised bleeding rate for the prophylaxis regimen was 6.19 episodes/year (95% CI, 3.69–10.38). The mean (SD) total consumption of turoctocog alfa (n = 34; excluding FVIII inhibitors) was 5,382.6 (7,180.1) IU/kg/year/patient; consumption was 4,133.1 (1,452.4) IU/kg/year/patient for prophylaxis. The effectiveness and safety profiles were comparable to those observed in other turoctocog alfa trials; effectiveness analysis and consumption were not affected by treatment regimens. Long-term use of turoctocog alfa therapy in clinical practice posed no newly identified safety issues and was effective for prophylaxis and treatment of bleeds in patients with haemophilia A in Japan.
Syntormon fuscipes Sympycninae
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon fuscipes

description: 252. Syntormon fuscipes (von Roser, 1840) (Sympycninae)
= Syntormon spicatum (von Roser, 1840).
= Syntormon spicatus Loew, 1857.
BG: Varna (listed as S. spicatum (von Roser) (Beschovski 1971)); Hrabrino village, Gorni Voden village, Yundola, Dedovo village, West Rhodopes Mts. (Kechev 2005); Tekirska river (Kechev 2014); Basha near Chirpan (Kechev & Ivanova 2015a); Rila Mts. (Hubenov 2016, 2017); GR: (Negrobov 1991); NM: Ohrid Lake (listed as S. spicatus Loew (Coe 1960)); RS: Ceremošnja (Pârvu 1997).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Additional file 1 of Reducing time to differentiated service delivery for newly-diagnosed people living with HIV in Kigali, Rwanda: a pilot, unblinded, randomized controlled trial
Creators: name: Ross, Jonathan
name: Anastos, Kathryn
name: Hill, Sarah
name: Remera, Eric
name: Rwibasira, Gallican N
name: Ingabire, Charles
name: Umwiza, Francine
name: Munyaneza, Athanase
name: Muhoza, Benjamin
name: Zhang, Chenshu
name: Nash, Denis
name: Yotebieng, Marcel
name: Murenzi, Gad
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1
Croisement d'analyses didactique et épistémologique des thèmes, transformations non totales, état d'équilibre, et critère d'évolution, dans les programmes et les manuels scolaires de Chimie au Baccalauréat Marocain
Creators: name: Ali Ouasri
Publisher: name: Zenodo
Year: 2024

description: Cette étude se veut un croisement d’analyses didactique-épistémologique de l’évolution des systèmes chimiques dans le programme de chimie au Baccalauréat (2006) en terms des trois thèmes: transformations non totales, équilibre chimique, et critère d’évolution spontané. Les transformations non totales sont caractérisées par un avancement final xf inférieur à l’avancement maximal xm, soit par un taux d’avancement final inférieur à 1, qui est un critère objectif et rigoureux que ce qui était dans l’ancien programe (1996). L’absence de référence à la modélisation des transformations non totales et l’ambiguïté maintenue sur les termes « réaction dans les deux sens » ou « réactions inverses » indique que la modification du modèle n’a été pas considéré par les concepteurs des programmes et des manuels scolaires comme un enjeu explicite du nouveau programme. L’état d’équilibre y est explicitement présenté comme étant l’état final de l’évolution d’un système chimique, caractérisé par la présence de toutes les espèces et par une valeur du quotient de réaction égale à la constante d’équilibre (Qr,eq = K). L’interprétation faite de l’état d’équilibre en termes de cinétique microscopique est explicite dans le programme n’est pas exigible des élèves. L’interprétation cinétique macroscopique basée sur l’égalité des vitesses des réactions inverses ne figure pas dans le programme, qui fournit une démarche basée sur le critère d’évolution pour expliquer et prévoir l’évolution des systèmes en proposant une interprétation dynamique de l’état d’équilibre qui va au-delà d’une simple perception des phénomènes. Pour les choix (modélisation, double regard macroscopique-microscopique), les intentions implicites des auteurs du programme ne sont pas clairement illustrées ni dans les contenus ni dans les programmes et les orientations pédagogiques officiels.
Syntormon metathesis Sympycninae
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon metathesis

description: 253. Syntormon metathesis (Loew, 1850) (Sympycninae)
BG: Gradina floodplain forest, near Vradina village (Kechev 2012b); NM: Ohrid Lake (Coe 1960, 1968).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Syntormon mikii Strobl 1899
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon mikii

description: 254. Syntormon mikii Strobl, 1899 (Sympycninae)
BG: Chirpan town (Kechev 2012a); Gradina floodplain forest (Kechev 2012b); Basha near Chirpan (Kechev & Ivanova 2015a); GR: (Negrobov 1991); HR: Spring Glavaš, Cetina River (Pollet & Ivković 2018).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Effect of hypomethylating agents on prognosis in acute myeloid leukemia patients treated with HAG priming: a systematic review and meta-analysis
Creators: name: Li, Jun
name: Fu, Shuying
name: Ye, Chunmei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: A combination of hypomethylation agents (HMA) and the HAG regimen (homoharringtonine, cytarabine, G-CSF) shows promise as a treatment for Acute Myeloid Leukemia (AML). Nevertheless, the clinical efficacy of this combined therapy in contrast to the HAG regimen alone remains uncertain. We conducted a meta-analysis of eligible studies comparing the clinical efficacy of these two regimens. A total of 38 studies involving 1195 AML patients were included in the analysis. Our findings suggest that the combination of hypomethylation agents (HMAs) and the HAG regimen resulted in a superior clinical response for newly diagnosed (ND) AML but not for relapsed/refractory (R/R) AML when compared to the HAG regimen alone. Subgroup analysis revealed that the pairing of azacitidine with the HAG regimen, as opposed to Decitabine with HAG, exhibited a higher response rate for ND AML when compared to the HAG regimen alone. Additionally, the combination of HMAs and the HAG regimen demonstrated good tolerability with a low early mortality rate and manageable adverse effects. Our meta-analysis suggests a potential trend towards improved efficacy when Azacitidine is added to the HAG regimen for treating acute myeloid leukemia (AML), especially in elderly or medically unfit patients. However, these findings should be interpreted as suggestive rather than definitive, emphasizing the need for further studies to confirm these preliminary results.
Syntormon monile Sympycninae
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon monile

description: 255. Syntormon monile (Haliday, 1851) (Sympycninae)
BG: Hrabrino village, West Rhodopes Mts. (Kechev 2005); Yundola, West Rhodope Mts. (Kechev 2006); Rila Mts. (Hubenov 2016, 2017).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
A need for greater awareness: a mixed methods study of patient and healthcare professional perspectives on the diagnosis journey for haemophagocytic lymphohistiocytosis (HLH)
Creators: name: Machado, Tracy
name: Lawrence, Judith
name: Eriksson, Daniel
name: Donohue, Jason
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: Mental Health
subject: Hematology

description: Our aim was to better understand and raise awareness of the diagnosis journey and quantify any barriers for timely diagnosis of haemophagocytic lymphohistiocytosis (HLH), to support patients’ struggle with diagnosis and reduce time to diagnosis. Patients diagnosed with, or caregivers for those diagnosed with primary or secondary HLH and physicians involved in the treatment of HLH were recruited. Quantitative interviews were undertaken with patients/caregivers to quantify key elements of the diagnosis journey, followed by qualitative interviews with participants. Interviews took place between March–May 2021. Thirty-three patients/caregivers and nine physicians took part in this mixed methods study. Lack of physician awareness of HLH was a common frustration for patients/caregivers, causing delayed diagnosis. All physicians indicated bone-marrow testing is a key step in the diagnosis process, and some patients/caregivers had frustrations around testing. Emergency care doctors, although not usually involved in the diagnosis process, were among the most-seen specialists by patients/caregivers. Patients/caregivers suggested potential improvements in available information, such as providing information on treatment options and condition management. Patients/caregivers and physicians agreed on the need to raise overall awareness of HLH signs/symptoms among priority groups of physicians to recognise how signs/symptoms can progress and develop. Improvements in the testing process and communication would directly impact the speed of diagnosis and support patients/caregivers during the diagnostic journey, respectively. Raising awareness of key issues, such as signs/symptoms, tests and diagnostic procedures, and improved communication and support for patients/caregivers, are key to speeding up HLH diagnosis and improving outcomes.
title: Ginseng :
title: Richtlinien für die Durchführung der Prüfung auf Unterscheidbarkeit, Homogenität und Beständigkeit.
titleType: Subtitle
Creators: name: International Union For The Protection Of New Varieties Of Plants,
Publisher: name: International Union for the Protection of New Varieties of Plants,
Year: 0
Subjects: Group identity.
Ginseng
New Varieties of Plants

description: Zweck dieser Richtlinien („Prüfungsrichtlinien“) ist es, die in der Allgemeinen Einführung (Dokument TG/1/3) und deren verbundenen TGP-Dokumenten enthaltenen Grundsätze in detaillierte praktische Anleitung für die harmonisierte Prüfung der Unterscheidbarkeit, der Homogenität und der Beständigkeit (DUS) umzusetzen und insbesondere geeignete Merkmale für die DUS-Prüfung und die Erstellung harmonisierter Sortenbeschreibungen auszuweisen.
Syntormon pallipes Sympycninae
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon pallipes

description: 256. Syntormon pallipes (Fabricius, 1794) (Sympycninae) - First record for European Turkey
ETR: Site 20: 1♂, 2♀; Site 23: 3♂; Site 28: 3♂, 4♀; Site 32: 11♂, 4♀; Site 33: 1♀; Site 36: 3♂, 4♀.
BA: Trebevic, Mostar, Krbljina (Strobl 1900); BG: Kamchiya River (Beschovski 1964); Dunes on the Bulgari-an Black Sea coast (Beschovski 1976); Dedevo village, Gorni Voden Village, Hrabrino village, West Rhodopes Mts. (Kechev 2006); Chirpan (Kechev 2012a); Gradina floodplain forest (Kechev 2012b); Basha near Chirpan (Kechev & Ivanova 2015a); Omurovska river near Gorno Belevo village (Kechev et al. 2014); Sarnena Sredna Gora Mt., Markovo and Naydenovo villages (Kechev 2016); “Sinite Kamani” Natura Park near Sliven (Kechev 2017b); Rila Mts. (Hubenov 2016, 2017); GR: (Negrobov 1991); Kerkini Lake (Kechev 2017a); NM: Ohrid Lake (Coe 1960); HR: Dubrovnik (Ragusa), Hvar Is. (Lesina), Zadar (Zara) (Strobl 1900); Plitvice (Coe 1960); Spring of Bijela rijeka, Plitvice Lakes; Spring of Krčić Stream, Krčić Stream; Roški Slap, Krka River; Spring Glavas, Cetina River; Spring Sveti Spas, Cetina River (Pollet & Ivković 2018); ME: Kolašin (Coe 1968); RO-DO: Furnica, Dobrodja (Pârvu 1995a, Skolka 2003); RS: Lazareva, Kučaj Mt. (Pârvu 1997).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Clinical characteristics of megaloblastic anemia with pancytopenia
Creators: name: Tang, Lin
name: Miao, Jing
name: Wang, Jinbi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Virology

description: In this study, we aimed to explore the clinical characteristics of patients with megaloblastic anemia and pancytopenia. Data on patient characteristics, laboratory examinations, clinical manifestations, and associated diseases were collected from Changzhou Hospital of Traditional Chinese Medicine. The participants were divided into two groups according to routine blood test results: megaloblastic anemia patients with pancytopenia (Group A) and megaloblastic anemia patients with simple anemia (Group B). The number of patients with fever and bleeding in Group A was much higher than that in Group B. Inpatient days and hospitalization costs in Group A were higher than those in Group B. White blood cell count, red blood cell count, haemoglobin level, and platelet count in Group A were lower than those in Group B. There were no significant differences in mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and serum levels of lactate dehydrogenase (LDH), total bilirubin (TBIL), direct bilirubin (DBIL), indirect bilirubin (IBIL), albumin (ALB), vitamin B12, folic acid, and ferritin between the two groups. The incidence of associated diseases, particularly pulmonary infections, was significantly higher in Group A than in Group B. There was no significant difference in the degree of bone marrow hyperplasia between the two groups. Patients with pancytopenia and megaloblastic anemia often developed infection and bleeding, which caused more severe anemia, higher hospitalization costs, and longer inpatient days. Early diagnosis and active treatment are required to reduce patient complications and costs.
Pre-treatment [18F]FDG PET/CT for assessing bone marrow involvement and prognosis in patients with newly diagnosed peripheral T-cell lymphoma
Creators: name: Chen, Jing
name: Zhao, Yi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Hematology
subject: Plant Biology

description: To explore the value of [18F]fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in assessing bone marrow involvement (BMI) and prognosis in newly diagnosed peripheral T-cell lymphomas (PTCLs) before treatment. This retrospective study included 201 eligible PTCLs who received pre-bone marrow biopsy (BMB) and PET/CT. The status of bone marrow (BM) by PET was assessed using a visual examination and a quantitative index (the maximal standardized uptake value [SUVmax] of BM divided by the SUVmax of the liver [M/L]). Totally 148 patients had no evidence of BMI by PET or BMB; BMI was detected by both methods in 16 patients. The sensitivity and specificity of PET/CT for patients with confirmed BMI by BMB were 43.2% and 90.2%, respectively (κ =  0.353). In addition, 25 patients assessed by PET/CT staging (having stage I to II disease) had no evidence of BMI detected by both PET/CT and BMB. Image-guided biopsy was also recommended when PET/CT showed a focal FDG uptake outside the iliac crest. Survival analysis revealed that BMB was significant for overall survival (OS) (P = 0.020) while M/L for both progression free survival (P = 0.002) and OS (P < 0.001). In multivariate analysis, M/L (HR 1.825, 95% CI 1.071-3.110, P = 0.027) was an independent prognostic factor for OS. There were no statistical differences at the genetic level about BMI confirmed by PET or BMB. PET/CT has a complementary role in assessing BMI and an ability to predict prognosis in PTCL patients.
title: Theme Session C – How do we adapt our approach to deal with novel contaminants in the marine environment?
Creators: name: ICES
Publisher: name: ASC 2024
Year: 2024
Subjects: Pressures, impacts, conservation, and management
ICES resources
Norwegian Sea (ICES Ecoregion)
Arctic Ocean (ICES Ecoregion)

description: Book of abstracts of theme session C:
How do we adapt our approach to deal with novel contaminants in the marine environment?Conveners: Mário Mil-Homens (Portugal), Víctor M. León (Spain), Claire Mason (United Kingdom)CM 725: Levels of PFASs in Fish and Crustaceans from the Western Scheldt in the NetherlandsCM 732: Impact of Plastic Waste on the Maritime Cultural Heritage in the Asia-specific region: Present Status and future challengesCM 735: Contaminants of emerging concern in the European Seas: an overview of available dataCM 828: Microplastics Distribution in Fish: Evidence from the Gulf of GuineaCM 887: Distribution of persistent organic pollutants sorbed by microplastics from coastal wastewaterCM 899: Per- and polyfluoroalkyl substances (PFAS) in surface sediments of Norwegian marine areasCM 976: Overlooked and unresolved: novel hydrocarbon contaminants in North Sea sediment cores and why not all carbon is ‘blue’CM 981: Legacy contaminant causing emerging concern – Heavy metal accumulation in ecosystem sentinelsCM 1098: Occurrence of contaminants of emerging concern in marine waters: a case study of two Portuguese estuaries and the coast in-betweenCM 1194: Pharmaceuticals in marine sediments of the central Portuguese continental shelf: An initial overview
Additional file 1 of Investigating factors associated to HBV/HIV co-infected patients in antiretroviral treatment clinic, in Northeast Ethiopia
Creators: name: Wasihun, Yitbarek
name: Asnake, Desalegn
name: Kebede, Natnael
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Supplementary Material 1
Syntormon pumilum Sympycninae
Creators: name: Kechev, Mihail
name: Naglis, Stefan
name: Tonguç, Alper
name: Pollet, Marc
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Dolichopodidae
Syntormon
Syntormon pumilum

description: 257. Syntormon pumilum (Meigen, 1824) (Sympycninae)
= Syntormon rufipes (Meigen, 1824).
BG: Topolite village (Beschovski 1967); Gorni Voden village, West Rhodopes Mts. (Kechev 2005, 2006); Chirpan (Kechev 2012a); Rila Mts. (Hubenov 2016, 2017); RO-DO: Sarica State Farm (Pârvu 1991); Furnica, Dobrodzha (listed as S. rufipes Meig. (Pârvu 1995a)).
description: Published as part of Kechev, Mihail, Naglis, Stefan, Tonguç, Alper & Pollet, Marc, 2020, Checklist of the Dolichopodidae (Diptera, Empidoidea) of the Balkan Peninsula with first records for Bulgaria, Montenegro, North Macedonia, and for the European part of Turkey, pp. 436-472 in Zootaxa 4819 (3) on page 464, DOI: 10.11646/zootaxa.4819.3.2, http://zenodo.org/record/4397053
Prognostic analysis according to European LeukemiaNet 2022 risk stratification for elderly patients with acute myeloid leukemia treated with decitabine
Creators: name: Kim, Mihee
name: Ahn, Seo-Yeon
name: Kim, TaeHyung
name: Jung, Sung-Hoon
name: Song, Ga-Young
name: Yang, Deok-Hwan
name: Lee, Je-Jung
name: Kim, Mi Yeon
name: Park, Ju Heon
name: Shin, Myung-Geun
name: Ahn, Jae-Sook
name: Kim, Hyeoung-Joon
name: Kim, Dennis Dong Hwan
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: This study aimed to evaluate the prognostic significance of the revised European LeukemiaNet (ELN)−2022 risk stratification model for 123 elderly acute myeloid leukemia (AML) patients treated with decitabine chemotherapy. Based on the ELN-2022 risk stratification, 15 (12.2%), 51 (41.5%), and 57 (46.3%) patients were classified as having favorable, intermediate, and high-risk AML, respectively. In comparison with the ELN-2017 risk stratification, the ELN-2022 risk stratification re-assigned 26 (21.1%) and three (2.4%) patients to the adverse and favorable risk groups, respectively. Survival analysis revealed distinctive overall survival (OS) outcomes among the ELN-2022 risk groups (6-month OS rate: 73.3%, 52.9%, and 47.7% for favorable, intermediate, and adverse risk, respectively; P = 0.101), with a parallel trend observed in the event-free survival (EFS) (6-month EFS rate: 73.3%, 52.9%, and 45.6% for favorable, intermediate, and adverse risk, respectively; P = 0.049). Notably, both OS and EFS in the favorable risk group were significantly superior in comparison to that of the adverse risk group (OS: P = 0.040, EFS: P = 0.030). Although the ELN-2022 C-index (0.559) was greater than the ELN-2017 C-index (0.539), the result was not statistically significant (P = 0.059). Based on the event net reclassification index, we consistently observed significant improvements in the ELN-2022 risk stratification for overall survival (0.21 at 6 months). In conclusion, the revised ELN-2022 risk stratification model may have improved the risk classification of elderly AML patients treated with hypomethylating agents compared to the ELN-2017 risk stratification model.