cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Parenting in a Pandemic: A Two-Part Study Exploring the Impact of COVID-Stress, Technoference and Paternal Mental Health on Parenting & Child Development.
Creators: name: ROBERTS, JOSHUA PAUL
Publisher: name: University of Surrey
Year: 2022

description: Abstract (Part A)

description:

description: This study aimed to understand the impact of COVID-19-related stress, parental technology
description: related interference in child-parent interaction – termed ‘technoference’ – and social media
description: use on parenting behaviours and child developmental outcomes. A secondary aim was to
description: explore the familial experience of the pandemic. Parents (n = 127) were recruited via an
description: online cross-sectional survey. Data was collected through questionnaires and open-ended
description: comments. Regression analysis indicated that greater parental COVID-19 related stress was
description: associated with more technoference and parent-proxy cognitive deficit scores in children
description: aged 6-11 years old, as well as lower levels of self-reported authoritative parenting, which
description: includes characteristics such as autonomy-granting and warmth. Greater social media use was
description: associated with permissive parenting behaviours, characterised by warmth but less discipline
description: or structure. Parental qualitative responses highlighted many challenges faced by families
description: during the pandemic, with negative mental health changes being the most frequently reported
description: difficulty. Findings and clinical implications are discussed in the context of managing the
description: effect of the pandemic on child development.

description:

description: Abstract (Part B)

description:

description: This study aimed to understand the impact of the COVID-19 pandemic and paternal
description: depressive symptoms on parenting behaviours and child developmental outcomes. It also
description: aimed to explore the paternal experience of the pandemic. Fathers (n = 87) were recruited for
description: an online cross-sectional survey. Data was collected through questionnaires and open-ended
description: comments. Regression analysis indicated; greater pandemic impact was associated with more
description: self-reported depressive symptoms in fathers. Higher COVID-19 impact scores, but not
description: paternal depression, was linked to less positive parenting behaviours in fathers. Paternal
description: pandemic impact and depression symptoms were negatively associated with child cognitive,
description: emotional, and behavioural outcomes. Qualitative responses from fathers noted that concerns
description: for their children, work and mental health were most prevalent during the pandemic.
description: However, several responders noted no change or positive change during the pandemic.
description: Clinical implications include targeted interventions and psychoeducation for fathers that
description: acknowledge difference in paternal coping and support seeking.
Detection of Viral −RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues
Creators: name: Salmikangas, Sami
name: Laiho, Jutta E.
name: Kalander, Kerttu
name: Laajala, Mira
name: Honkimaa, Anni
name: Shanina, Iryna
name: Oikarinen, Sami
name: Horwitz, Marc S.
name: Hyöty, Heikki
name: Marjomäki, Varpu
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2021

description: The current methods to study the distribution and dynamics of viral RNA molecules inside infected cells are not ideal, as electron microscopy and immunohistochemistry can only detect mature virions, and quantitative real-time PCR does not reveal localized distribution of RNAs. We demonstrated here the branched DNA in situ hybridization (bDNA ISH) technology to study both the amount and location of the emerging −RNA and +RNA during acute and persistent enterovirus infections. According to our results, the replication of the viral RNA started 2–3 h after infection and the translation shortly after at 3–4 h post-infection. The replication hotspots with newly emerging −RNA were located quite centrally in the cell, while the +RNA production and most likely virion assembly took place in the periphery of the cell. We also discovered that the pace of replication of −RNA and +RNA strands was almost identical, and −RNA was absent during antiviral treatments. ViewRNA ISH with our custom probes also showed a good signal during acute and persistent enterovirus infections in cell and mouse models. Considering these results, along with the established bDNA FISH protocol modified by us, the effects of antiviral drugs and the emergence of enterovirus RNAs in general can be studied more effectively.
Supplementary information - data sources and processing from Rapid indirect solar responses observed in the lower atmosphere
Creators: name: R. Giles Harrison
name: Lockwood, Michael
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Atmospheric Sciences
subject: FOS: Earth and related environmental sciences

description: Establishing clear evidence of solar-induced lower atmosphere effects is hampered by the small 11-year solar cycle responses, typically swamped by meteorological variability. Strong 27-day cyclic changes are exploited here instead. During the 2007/8 minimum in solar activity, regular 27-day lighthouse-like sweeps of energetic particles crossed the heliosphere and Earth, followed by a burst of solar ultraviolet radiation. Averaging the atmospheric responses at UK sites reveals immediate cooling in the troposphere after the peak energetic particle flux, followed by warming in the stratosphere. Regionally, this is accompanied by zonal wind changes, and temperature changes beneath cloud at the same time. Of two possible rapid distinct routes of solar influence—photochemical (through ozone) and atmospheric electrical (through low level clouds)—the ozone route does not provide a phase-locked response but the electrical route is supported by observed phase-locked thickening of low level clouds. These findings have potential value to weather forecasting.
Volunteering in school science lessons: expectations and experiences of university students
Creators: name: Cook, Emily
name: Fluke, Christopher
name: Chang, Rosemary
name: Mann, Llew
Publisher: name: Swinburne
Year: 2024

description: This study investigates university students studying engineering, science and ICT degrees and their experiences volunteering in a school-based science/maths outreach program. The aims of the program are to increase enthusiasm in science and maths in the middle years of education and promote science as a career choice. The volunteers support these aims by providing specialist knowledge and assistance to the class teacher, interacting with the school pupils and being role models. They are placed in a class for a ten week period during which they build relationships with the pupils and are encouraged to answer questions not only on the topics being studied in class, but also on their own experiences studying and their pathways to higher education. The benefits of this program to school students have been studied but the outcomes sought and experienced by the university students are less well known. To understand why students volunteer and what benefits they experience during their school placements. Volunteers were invited to take part in focus groups before and after their school placements. During the pre-placement focus group they were prompted to discuss their reasons for volunteering. In the post-placement session they were asked about why they had participated and asked to reflect on what they had gained from their experiences. The discussion was recorded and transcribed and the transcript coded to identify key themes. Students volunteered for a variety of reasons with most students having more than one motivating factor. Reasons included altruism, enjoyment of science, a desire to develop confidence and public speaking skills, and to enhance their employability. Volunteers participated in this school-based mentoring program for the expected motivational reasons described in the literature. After placements volunteers had improved their communication skills and reinforced their subject knowledge. This paper concludes that participation in this outreach program is of value to university students in terms of knowledge, skills and confidence gained but that they are often unaware of many of the skills they have demonstrated and developed.
The Collaborative Role of the Presbyteral Council in the Governance of a Diocese
Creators: name: Okosun, John E.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: Presbyteral Council
Collaboration in Church Governance

description: Abstract This thesis aims at establishing the juridical significance of the collaborative role of the presbyteral council in diocesan governance and proposes some concrete means through which this collaboration may be fostered in the particular Churches. It traces the historical antecedents to the presbyteral council and posits that since the beginning of Christianity, those who govern in the Church have always been assigned some kind of consultative and collaborative organs, made up of priests in most cases, and they were obliged to hear or obtain their consent in more important matters. Hence at different times in history, the presbyteral colleges, the cathedral chapter and the diocesan consultors emerged as organs which played this role. With the Second Vatican Council, there was a call for a new consultative body which would reflect the theology of Vatican II by focusing on unity of mission between bishops and priests; accordingly the council fathers called for the establishment of the presbyteral council. The thesis takes a step further to give an expository analysis of the current law on the presbyteral council, it alludes that the presbyteral council which represents the presbyterium of the diocese, is consultative in nature and is called to assist the diocesan bishop in the governance of the diocese through advice. It says categorically that, it is obligatory for every diocese to establish this council and makes it clear that the statutes of the presbyteral council are important instruments in the realization of the goals of this council. It then analysis the statutes of thirty one North American archdioceses and highlights those elements which should form part of good statutes, these include the nature, role, manner of acting and the method of determining membership of the council. Finally, it brings out other factors which could help to foster the collaborative role of the council in the governance of the local Church; these include the way priests are formed, the style of governance of the bishop, the life style of priests, the way priests are prepared for the election of council members and the ability of members to assert their proper role.
Supplementary document for Optical Tunnels: Long-range Optical Trapping and Manipulation - 5431951.pdf
Creators: name: Lialys, Laurynas
name: Lialys, Justinas
name: Fardad, Shima
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Applied Physics

description: Yeast translation and Trap Stiffness vs location
Les représentations de l’homosexualité dans la télésérie « Les hauts et les bas de Sophie Paquin »
Creators: name: Vacias, Vivianne
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Télévision
Média
Homosexualité
Gai
Lesbienne
Représentation
Sexualité
Hétéronormativité
Analyse de contenu
Québec

description: L'écran de télévision peut être perçu comme étant un miroir reflétant les climats sociaux et politiques d'une société. Alors, que représente concrètement le contenu de la télévision lorsqu'il concerne l'image d'individus marginalisés au sein de la société, comme les homosexuels? Dans un contexte hétéronormé, comment l'homosexualité est-elle représentée dans la télésérie « Les hauts et les bas de Sophie Paquin »? Quelle est cette représentation et comment s'inscrit-elle comme discours par rapport à l'hétéronormativité? Avec comme fondement théorique les travaux de Richard Dyer et de Michel Foucault, nous avons effectué une analyse de contenu et des discours de l'ensemble des saisons (4) de la télésérie québécoise. Nos résultats montrent que la représentation de l'homosexualité dans l'émission va au-delà de celle simplement libérale sans pour autant constituer un total contre discours par rapport à l'hétéronormativité. Ce portait offre un point de référence sur la représentation de l'homosexualité à la télévision québécoise.
Scalable and Interpretable Identification of Minimal Undesignable RNA Structure Motifs with Rotational Invariance
Creators: name: Zhou, Tianshuo
name: Tang, Wei Yu
name: Malik, Apoorv
name: Mathews, David H.
name: Huang, Liang
Publisher: name: arXiv
Year: 2024
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: RNA design aims to find a sequence that folds with highest probability into a designated target structure. However, certain structures are undesignable, meaning no sequence can fold into the target structure under the default (Turner) RNA folding model. Understanding the specific local structures (i.e., "motifs") that contribute to undesignability is crucial for refining RNA folding models and determining the limits of RNA designability. Despite its importance, this problem has received very little attention, and previous efforts are neither scalable nor interpretable. We develop a new theoretical framework for motif (un-)designability, and design scalable and interpretable algorithms to identify minimal undesignable motifs within a given RNA secondary structure. Our approach establishes motif undesignability by searching for rival motifs, rather than exhaustively enumerating all (partial) sequences that could potentially fold into the motif. Furthermore, we exploit rotational invariance in RNA structures to detect, group, and reuse equivalent motifs and to construct a database of unique minimal undesignable motifs. To achieve that, we propose a loop-pair graph representation for motifs and a recursive graph isomorphism algorithm for motif equivalence. Our algorithms successfully identify 24 unique minimal undesignable motifs among 18 undesignable puzzles from the Eterna100 benchmark. Surprisingly, we also find over 350 unique minimal undesignable motifs and 663 undesignable native structures in the ArchiveII dataset, drawn from a diverse set of RNA families. Our source code is available at https://github.com/shanry/RNA-Undesign and our web server is available at http://linearfold.org/motifs.
A Priori Uncertainty Quantification of Reacting Turbulence Closure Models using Bayesian Neural Networks
Creators: name: Pash, Graham
name: Hassanaly, Malik
name: Yellapantula, Shashank
Publisher: name: arXiv
Year: 2024
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Machine Learning (cs.LG)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: While many physics-based closure model forms have been posited for the sub-filter scale (SFS) in large eddy simulation (LES), vast amounts of data available from direct numerical simulation (DNS) create opportunities to leverage data-driven modeling techniques. Albeit flexible, data-driven models still depend on the dataset and the functional form of the model chosen. Increased adoption of such models requires reliable uncertainty estimates both in the data-informed and out-of-distribution regimes. In this work, we employ Bayesian neural networks (BNNs) to capture both epistemic and aleatoric uncertainties in a reacting flow model. In particular, we model the filtered progress variable scalar dissipation rate which plays a key role in the dynamics of turbulent premixed flames. We demonstrate that BNN models can provide unique insights about the structure of uncertainty of the data-driven closure models. We also propose a method for the incorporation of out-of-distribution information in a BNN. The efficacy of the model is demonstrated by a priori evaluation on a dataset consisting of a variety of flame conditions and fuels.
The General Principle behind Magnetization-induced Second-Order Topological Corner States in the Kane-Mele Model
Creators: name: Miao, Cheng-Ming
name: Liu, Lizhou
name: Wan, Yu-Hao
name: Sun, Qing-Feng
name: Zhang, Ying-Tao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We propose a general principle for realizing second-order topological corner states in the modified Kane-Mele model with magnetization. It is demonstrated that the sign of the edge Dirac mass depends on the magnetization of the edge sublattice termination. By adjusting the directions of magnetization according to the type of sublattice at the termination of two edges, a mass domain wall can be induced in the presence of topological corner states at an arbitrary position. All previous work on introducing magnetization in the Kane-Mele model to realize second-order topological corner states can be explained by the presence of the Dirac mass domain wall with opposite signs. Applying this principle, we design square-shaped and armchair-type hexagon-shaped graphene nanoflakes with edge magnetization, allowing for the emergence of second-order topological corner states. Our findings serve as a general theory, demonstrating that the realization of second-order topological corner states is not limited by boundary type or nanoflake shape.
A thesis of clinical research and practice: Part A: [An Online PTSD Psycho-Education Tool for Hosts of Ukrainian Refugees: A Feasibility Study]; Part B: [The Mental Health of Ukrainian Refugees: A Narrative Review]; Part C: Summary of clinical practice and assessments
Creators: name: Ellis, Emily
Publisher: name: University of Surrey
Year: 2024
Subjects: PTSD
Mental Health
Ukraine

description: The full-scale Russian invasion of Ukraine began in February 2022 and has been ongoing since. This has resulted in 6.5 million Ukrainian refugees worldwide which has prompted other countries to employ resettlement schemes for Ukrainian’s fleeing war. Within the United Kingdom (UK) the Homes for Ukraine scheme was opened, whereby members of the public can offer up space within their home to host Ukrainian refugees. There has been little support from the government for hosts and a growing body of research suggesting that Ukrainian refugees may develop mental health problems. This thesis aimed to explore how to support hosts and summarise the current mental health status of Ukrainian refugees. Part A of this thesis presents an empirical paper that evaluates the acceptability of a PTSD psycho-education tool for hosts of Ukrainian refugees and the feasibility of research methodology, and procedures designed to explore its efficacy. The results suggest that the current methodology is not feasible for a full-scale evaluation trial, due to difficulties with recruitment and data collection. However, the PTSD psycho-education tool proved acceptable to hosts. Part B of this thesis presents a narrative review of research exploring the mental health of Ukrainian refugees. The review synthesises a growing body of literature, identifying four themes prevalent in the current mental health of Ukrainian refugees: General Psychological Distress, Common Mental Health Problems, PTSD and Trauma and coping and Resilience. The review highlights the increased vulnerability of Ukrainian refugees in developing mental health problems and identifies a number of factors associated with this. Finally, the review discusses the implications of these findings on future research and support for this population.
Realization of the Non-endpoint Majorana Bound States in an Extended Kitaev Chain
Creators: name: Zhang, Xuan
name: Miao, Cheng-Ming
name: Sun, Qing-Feng
name: Zhang, Ying-Tao
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the energy levels and transport properties of an extended Kitaev chain with a phase gradient. It is demonstrated that the hopping phase difference can effectively induce the generation of Majorana bound states, which are located at the non-endpoint sites of the chain. The number and positions of the non-endpoint Majorana bound states can be modulated by the hopping phase difference and initial hopping phase, respectively. In addition, we propose a protocol to realize topological braiding operation by exchanging the positions of two Majorana bound states in the extended Kitaev ring. Furthermore, we also implement the braiding of any two of the multiple Majorana bound states in the extended Kitaev double rings.
Chemical Safety Through the Lens of Omics: Machine Learning Approaches for Pathway Analysis and Predictive Modelling
Creators: name: Liu, Yufan
Publisher: name: University of Surrey
Year: 2024
Subjects: Multi-Omics
Large Language Models
Quantitative Structure-Activity Relationships
Machine Learning
Toxicology

description: The emergence of omics technologies has transformed how we study and characterise the responses of biological systems to xenobiotics. Using pathways analysis to interpret responses through bioinformatics approaches and machine learning methods to build predictive models have become new paradigms for processing complex omics data. In this study, three different machine learning approaches were proposed to investigate the relationship between chemicals and their regulatory pathways.The first project presents a Quantitative Structure-Activity Relationships (QSAR) model that innovatively predict regulatory pathways of chemicals. The findings underscore the potential of predictive chemical-pathway associations, enhancing our understanding of chemical mechanisms of action and their side effects. While QSAR model gives satisfactory results, data limitations persist, such as the factors that may affect the pathways, which are lack of curation. Hence introducing the need of Natural Language Processing model for information extraction from omics literature. A semi-automated structured data retrieval method was developed, effectively processing 13,234 articles to extract critical omics study details and results. This approach facilitated the creation of a comprehensive dataset that could significantly advance the understanding of toxicological mechanisms and biological responses to various perturbations.The third project provides an in-depth exploration of the factors that influence pathways and showcases a multivariate multi-omics integration to enhance chemical risk assessments. By integrating transcriptomics, proteomics, and phosphoproteomics data, the study identifies dose-dependent and temporal variances in response to chemical exposures. Advanced analytical techniques have allowed for a detailed understanding of the underlying mechanisms, showcasing the utility of omics technologies in predicting adverse outcomes.The implications of these findings are significant, offering a more systematic approach to toxicological assessments and a better understanding of biological responses to chemicals. This research not only supports the reduction of animal testing but also enhances the development of more precise predictive models for chemical safety.
Portable, heterogeneous ensemble workflows at scale using libEnsemble
Creators: name: Hudson, Stephen
name: Larson, Jeffrey
name: Navarro, John-Luke
name: Wild, Stefan M.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: libEnsemble is a Python-based toolkit for running dynamic ensembles, developed as part of the DOE Exascale Computing Project. The toolkit utilizes a unique generator--simulator--allocator paradigm, where generators produce input for simulators, simulators evaluate those inputs, and allocators decide whether and when a simulator or generator should be called. The generator steers the ensemble based on simulation results. Generators may, for example, apply methods for numerical optimization, machine learning, or statistical calibration. libEnsemble communicates between a manager and workers. We overview the unique characteristics of libEnsemble as well as current and potential interoperability with other packages in the workflow ecosystem. We highlight libEnsemble's dynamic resource features: libEnsemble can detect system resources, such as available nodes, cores, and GPUs, and assign these in a portable way. These features allow users to specify the number of processors and GPUs required for each simulation; and resources will be automatically assigned on a wide range of systems, including Frontier, Aurora, and Perlmutter. Such ensembles can include multiple simulation types, some using GPUs and others using only CPUs, sharing nodes for maximum efficiency. We also describe the benefits of libEnsemble's generator--simulator coupling, which easily exposes to the user the ability to cancel, and portably kill, running simulations based on models that are updated with intermediate simulation output. We demonstrate libEnsemble's capabilities, scalability, and scientific impact via a Gaussian process surrogate training problem for the longitudinal density profile at the exit of a plasma accelerator stage. The study uses gpCAM for the surrogate model and employs either Wake-T or WarpX simulations, highlighting efficient use of resources that can easily extend to exascale.
Solastalgia
Creators: name: ROLLE, MARY ELLIOTT
Publisher: name: University of Surrey
Year: 2021

description: "The first part of this thesis is a climate change novel called Solastalgia. In 2058, climatologist Clyde Factor travels to London to join the prestigious but mysterious Institute. Only after he arrives is he told that the job will involve time travel. Paired with Eleanor DeQuincy, a hard-headed criminologist, Clyde becomes part of team three, whose study proposes using violent ecoterrorist attacks to incite early action on climate change and save the human species. Six teams compete to have their project chosen for implementation, altering the course of history. But only one project will be selected, and time is running out. Factor and DeQuincy travel to a number of disturbing events, watching horrendous effects unfold with a disquieting prior knowledge of what will happen, and a mandate not to intervene. These horrors are balanced by opportunities to see the world as it had been when they were younger, but these moments also remind them of all they’ve lost.
description: The second part of this thesis is a critical commentary exploring the relationship between climate fiction and readers, particularly how climate fiction can reflect the personal psychological journeys of authors, characters, and readers. It provides an overview of ecocriticism and climate fiction criticism, and analyses the ways in which climate fiction overlaps with protest fiction, discussing the import of portraying affect and trauma in climate fiction. Finally, these elements are discussed in the context of the creative project, Solastalgia. Overarchingly, the commentary argues that climate fiction is a form of protest fiction in which authors and readers interact in traumatic future worlds that reflect and predict their personal experiences within the slow trauma of climate change, and that careful use of trauma and affect can heighten the emotional connection between story and reader, which can make climate fiction more effective protest fiction."
Ultrafast Dynamics of Bilayer and Trilayer Nickelate Superconductors
Creators: name: Li, Y. D.
name: Cao, Y. T.
name: Liu, L. Y.
name: Peng, P.
name: Lin, H.
name: Pei, C. Y.
name: Zhang, M. X.
name: Wu, H.
name: Du, X.
name: Zhao, W. X.
name: Zhai, K. Y.
name: Zhao, J. K.
name: Lin, M. -L.
name: Tan, P. H.
name: Qi, Y. P.
name: Li, G.
name: Guo, H. J.
name: Yang, Luyi
name: Yang, L. X.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In addition to the pressurized high-temperature superconductivity, bilayer and trilayer nickelate superconductors Lan+1NinO3n+1 (n = 2 and 3) exhibit many intriguing properties at ambient pressure, such as orbital-dependent electronic correlation, non-Fermi liquid behavior, and density-wave transitions. Here, using ultrafast reflectivity measurement, we observe a drastic difference between the ultrafast dynamics of the bilayer and trilayer nickelates at ambient pressure. Firstly, we observe a coherent phonon mode in La4Ni3O10 involving the collective vibration of La, Ni, and O atoms, which is absent in La3Ni2O7. Secondly, the temperature-dependent relaxation time diverges near the density-wave transition temperature of La4Ni3O10, in drastic contrast to kink-like changes in La3Ni2O7. Moreover, we estimate the electron-phonon coupling constants to be 0.05~0.07 and 0.12~0.16 for La3Ni2O7 and La4Ni3O10, respectively, suggesting a relatively minor role of electron-phonon coupling in the electronic properties of Lan+1NinO3n+1. Our work not only sheds light on the relevant microscopic interaction but also establishes a foundation for further studying the interplay between superconductivity and density-wave transitions in nickelate superconductors.
title: Advanced catalysts for a low-carbon future
title: exploring new routes for biomass valorisation 291
titleType: Subtitle
Creators: name: JIN, WEI
Publisher: name: University of Surrey
Year: 2021

description: Biomass valorisation is becoming an appealing topic considering the gradual depletion of fossil fuel and the severe environmental deterioration aroused from the massive emission of greenhouse gases (GHGs). Deoxygenation is a fundamental reaction in the upgrading of bio-oil to produce hydrocarbon fuels or high-value chemicals. The removal of oxygen in bio-oil could increase the heating value, enhance the thermal and chemical stability, reduce corrosivity, etc. making the upgraded bio-oil suitable as fuel or blending fuel. Hence, in this thesis, the deoxygenation of raw bio-oil and hydrodeoxygenation of bio-oil model compounds are investigated. Pt/NC are proven to be effective catalysts for the deoxygenation of palm oil to produced bio-hydrogenated diesel (BHD) under optimised reaction conditions. The enhanced interaction between reactants and nitrogen doped support (NC) explains the higher decarbonylation and/or decarboxylation (DeCOx) selectivity. The hydrodeoxygenation of guaiacol with H2 generated from aqueous phase reforming (APR) of methanol and glycerol is conducted in a high-pressure batch reactor. Higher conversion is achieved for methanol as hydrogen source, owing to the higher H2 selectivity from APR process. The interaction of Ni and Pt could enhance the dehydroxylation and hydrogenation in the HDO process, and thus promote deoxygenation efficiency for HDO using methanol as hydrogen source. A novel method for “H2-free” HDO suppressing the external H2 supply is proposed and this concept feasibility is tested over carbon supported non-noble and noble metal catalysts. There is still a large room for improvement in terms of deoxygenation efficiency, but the proposed HDO method is highly recommendable opening new cost-effective alternative for the biomass valorisation. It is worth emphasising the hydrogen transfer route is investigated by the analysis of gas products and the distribution of isotope in isotopic labelling analysis. D/H transfer happens in the catalytic HDO process evidencing the role of the hydrogen donor to produce H2 in-situ. Overall, this thesis showcases appealing strategies for biomass valorisation and how an optimal catalyst design is vital to unlock the potential of bio-resources. In fact, this work is conceived to serve as guidance for the successful design of advanced catalysts to pursue a low carbon future as ultimate goal.
A Thesis of Clinical Research and Practice: Part A: [Understanding romantic relationships in people with a learning disability who identify as LGBTQ+]. Part B: [How are the sexual and intimate relational needs of people with learning disabilities experienced by family members: A qualitative evidence synthesis]. Part C: Summary of clinical practice and assessments
Creators: name: Tucker, Rachel Lydia
Publisher: name: University of Surrey
Year: 2024
Subjects: Learning Disabilities
LGBTQ+
Sexuality
Romantic Relationships

description: Desires for emotional closeness, romantic relationships and sexual experiences are all considered fundamental human needs, but often people with learning disabilities are not afforded the same opportunities to develop and explore this important aspect of life. This thesis aimed to research the intimate and relational experiences of people with learning disabilities, and to learn about the supportive and challenging processes that facilitate or hinder such experiences. Part one of this portfolio presents an empirical paper that explores the experiences of romantic relationships in people with learning disabilities that identify as LGBTQ+. The findings suggest that experiences are limited and have often been harmful, thus leading to feelings of vulnerability and isolation. A sense of belonging, connecting with a community, and feeling well supported led to feelings of safety and an ability to express identity authentically. The empirical paper highlighted the impact of inadequate sex and relationship education, professional explicit and implicit biases and lack of specialism and training in the area. Part two presents a qualitative synthesis of the ways in which family systems perceive the relational and sexual needs and development of their loved one with a learning disability. The findings of this review suggest that many families fear their loved one with a learning disability will be harmed and they struggle to adapt to changing needs at crucial times of transition which as a result leads to greater restrictions, discriminatory attitudes, and infantilising narratives. Some families felt able to support with this change, celebrating and supporting romantic relationships and sexual development, however this ability seemed highly dependent upon wider contextual factors such as culture, politics, and parenting approach.
ДИСПОЗИТИВНОСТЬ В ЮРИДИЧЕСКОЙ ДОКТРИНЕ РОССИЙСКОЙ ФЕДЕРАЦИИ
Creators: name: Катомина Виктория Александрровна
Publisher: name: Вестник Саратовской государственной юридической академии
Year: 2020
Subjects: диспозитивность
правоприменительная деятельность
прин- цип права
метод правового регулирования
нормы права
свобода усмотрения
выбор поведения

description: Введение: в статье проведен теоретический анализ юридической природы диспо- зитивности. Автор отмечает, что неоднозначность мнений по вопросу об истоках диспозитивности в юридическом процессе порождает многозначность подходов к определению характера этого явления. Термин диспозитивность употребляется в разных, хотя и близких, значениях. Цель: исследовать сущность идеи диспозитив- ности как свободы усмотрения субъекта права в определении стратегии, тактики и выбора варианта поведения; выявить признаки данного правового феномена. Ме- тодологическая основа: диалектический метод, системный подход, формально- юридический метод. Результаты: доказано, что диспозитивность — сложное многогранное правовое явление, включающее в себя ряд взаимосвязанных аспектов. Диспозитивность выражается в форме принципа права, института права, свойства, присущего нормам права и субъектам правоотношения, черты метода правового ре- гулирования, разновидности юридических норм, частного случая правового начала. Выводы: значимость идеи диспозитивности очевидна и заключается в том, что она служит средством обеспечения и защиты субъективных прав и охраняемых законом интересов; предоставляет широкие возможности в выборе вариантов поведения субъектам права в правоприменительной деятельности и др. Диспозитивность оказывает регулирующее воздействие на участников правоотношений. Характер воздействия диспозитивности зависит от того, в каком аспекте она выступает.
МЕСТО И РОЛЬ МЕХАНИЗМА В СИСТЕМЕ ЮРИДИЧЕСКОЙ ОТВЕТСТВЕННОСТИ ОРГАНОВ ПУБЛИЧНОЙ ВЛАСТИ
Creators: name: Маркунин Роман Сергеевич
Publisher: name: Вестник Саратовской государственной юридической академии
Year: 2020
Subjects: механизм правового регулирования
система юридической от- ветственности
органы публичной власти
дискреционные полномочия
депутат Государственной Думы
нормативно-правовой акт

description: Введение: в статье рассматривается вопрос соотношения механизма и системы юридической ответственности. Раскрывается роль механизма реализации от- ветственности и его значение в общей системе. Цель: на основе анализа научной литературы и действующего законодательства установить значение механизма реализации юридической ответственности в рамках одноименной системы, показать имеющиеся проблемы в действующих системах ответственности различных органов публичной власти и обозначить возможные пути их решения. Методологическая основа: используется совокупность методов научного познания, среди которых можно выделить: формально-юридический метод, метод сравнительно-правового анализа, системный, диалектический и иные. Результаты: разграничены категории «систе- ма» и «механизм» на примере юридической ответственности органов власти. По итогам проведенного исследования освещены имеющиеся проблемы в системе юриди- ческой ответственности органов публичной власти. Выводы: механизм реализации юридической ответственности позволяет показать взаимодействие и особенности функционирования структурных элементов системы ответственности, а также дает возможность делать выводы о результативности правового регулирования в целом.
title: Does prehabilitation improve cardiopulmonary exercise performance in patients undergoing neoadjuvant treatment and surgery for oesophagogastric cancer?
title: A randomised controlled trial
titleType: Subtitle
Creators: name: ALLEN, SOPHIE
Publisher: name: University of Surrey
Year: 2021

description: Neoadjuvant chemotherapy (NAC) and surgery improves survival in patients with locally advanced oesophagogastric (OG) cancer. Adequate cardiopulmonary fitness is vitally important to patients undergoing OG cancer resection as this major operation is associated with a large metabolic stress response and significant morbidity. Side effects of NAC are a reduction in cardiopulmonary fitness, skeletal muscle loss, and poor quality of life (QOL). Cardiopulmonary fitness can be objectively measured by cardiopulmonary exercise testing (CPET); an established, non-invasive, and safe method of assessing patients’ cardiopulmonary reserve prior to surgery. Reduced anaerobic threshold (AT) and peak oxygen uptake (peak VO2) are associated with increased morbidity and poor functional outcomes in patients undergoing major surgery. NAC is associated with an AT decrease of 2ml/kg/min in OG cancer patients.
description: A parallel-arm, randomised, controlled trial was conducted to determine whether a prehabilitation programme improves CPET performance prior to surgery in patients with OG cancer undergoing NAC. Patients were randomised to receive a 15-week prehabilitation programme (Prehabilitation) or standard care (Control). Prehabilitation comprised twice-weekly supervised plus thrice-weekly home exercise sessions (aerobic and resistance based) and six sessions of medical coaching. Secondary outcomes included change in skeletal muscle mass observed via computed tomography following NAC, anthropometric measures including hand-grip strength (HGS), QOL, insulin resistance (using HOMA-IR), and clinical outcomes.
description: There was a significant difference in peak VO2 change following NAC (Prehabilitation +0.5% versus Control -10.0%;p=0.022). No difference in AT was observed. Prehabilitation subjects experienced less skeletal muscle loss despite NAC and showed improvements in functional outcomes (HGS). There were significant improvements in the Prehabilitation group across a multitude of QOL parameters.
description: There were no exercise-related adverse events, and good programme compliance was observed. This study has thus shown that an exercise and psychological prehabilitation programme is safe and achievable in OG patients receiving NAC prior to surgical resection.
Generalized Euler-Maclaurin formula and Signatures
Creators: name: Bellingeri, Carlo
name: Friz, Peter K.
name: Paycha, Sylvie
Publisher: name: arXiv
Year: 2024
Subjects: subject: Probability (math.PR)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 60L90, 60L10, 26A45

description: The Euler-Maclaurin formula which relates a discrete sum with an integral, is generalised to the setting of Riemann-Stieltjes sums and integrals on stochastic processes whose paths are a.s. rectifiable, namely, continuous and with bounded variation. For this purpose, new variants of the signature are introduced, such as the flip and the sawtooth signature. The counterparts of the Bernoulli numbers that arise in the classical Euler-Maclaurin formula are shown to be the integration constants in the repeated integration by parts which ``recursively minimise the error'' at every truncation level.
description: Reorganised the order of the sections, typos corrected
Supplementary document for Optical Tunnels: Long-range Optical Trapping and Manipulation - 5431951.pdf
Creators: name: Lialys, Laurynas
name: Lialys, Justinas
name: Fardad, Shima
Publisher: name: Optica Publishing Group
Year: 2021
Subjects: Applied Physics

description: Yeast translation and Trap Stiffness vs location
From the Conformal Anomaly to the Virasoro Algebra
Creators: name: Maibach, Sid
name: Peltola, Eveliina
Publisher: name: arXiv
Year: 2024
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 17B68, 81T40, 30F45, 60D05, 81T50

description: The conformal anomaly and the Virasoro algebra are fundamental aspects of 2D conformal field theory and conformally covariant models in planar random geometry. In this article, we explicitly derive the Virasoro algebra from an axiomatization of the conformal anomaly in terms of real determinant lines, one-dimensional vector spaces associated to Riemann surfaces with analytically parametrized boundary components. Here, analytical orientation-preserving diffeomorphisms and deformations of the circle naturally act on the boundary components. We introduce a sewing operation on the real determinant lines over the semigroup of annuli, which then induces central extensions of the diffeomorphism group, as well as of the complex deformations.
 Our main theorem shows that on the one hand, the cocycle associated to the central extension of diffeomorphisms is trivial, while on the other hand, the Lie algebra cocycle associated to the central extension of complex deformations is nontrivial, yielding the imaginary part of the Gel'fand-Fuks cocycle. We thus answer a question, partly negatively and partly affirmatively, discussed by Andre Henriques and Dylan Thurston in 2011. The proof uses concrete computations, which we aim to be accessible to a wide audience.
 We also show an explicit relation to loop Loewner energy, anticipating the real determinant lines to be pertinent to locally conformally covariant (Malliavin-Kontsevich-Suhov) measures on curves and loops, as well as to Kähler geometry and geometric quantization of moduli spaces of Riemann surfaces. Inherently, the conformal anomaly and real determinant line bundles are expected to be universal, following a classification of modular functors.
description: v3: 44 pages, 4 figures; minor corrections following referees' reports; to appear in Proc. Lond. Math. Soc
Tiny non-Leighton complexes
Creators: name: Dergacheva, Natalia S.
name: Klyachko, Anton A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Geometric Topology (math.GT)
subject: Combinatorics (math.CO)
subject: Group Theory (math.GR)
subject: FOS: Mathematics

description: How complex must two finite 2-complexes be to admit a common, but not finite common, covering? We obtain an almost answer: the minimum possible number of triangles in a pseudo-simplicial triangulation of each complex is 3, 4, or 5.
description: 5 pages. A Russian version of this paper is at http://halgebra.math.msu.su/staff/klyachko/papers.htm . V4: Minor misprint corrections
Improving Integrally Heated Composite Tooling Through Cold Sprayed Copper Coatings and Heat Transfer Simulations
Creators: name: Baril-Gosselin, Simon
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2013
Subjects: Composite
Cold spray
Pulsed gas dynamic spraying
Composite tooling
Manufacturing

description: Integrally heated composite tooling (IHCT) is seen as a low cost alternative to autoclave manufacturing of polymer matrix composites (PMCs). IHCTs consist of a composite tool heated by surface heaters; temperature distribution is ensured by a thermally conductive metallic layer. The main original contributions of this thesis was the development of a new method for applying copper coatings onto carbon fibre/epoxy PMCs using pulsed gas dynamic spraying, the production of larger size samples, and the characterisation of the performance of the coatings and laminates obtained. It was shown that this method has potential for producing the thermally conductive layer in an IHCT. Another contribution was the characterisation of parameters affecting temperature distribution across IHCTs through heat transfer simulations, leading to guidelines for IHCT design.
Modelling the influence of weather and climate in human disease: salmonellosis today and tomorrow
Creators: name: Gonzalez Villeta, Laura Cristina
Publisher: name: University of Surrey
Year: 2024

description: The significance of the environment within the One Health approach for addressing emerging health challenges is gaining widespread recognition. The observed seasonal pattern in the incidence of certain infectious diseases, such as salmonellosis, prompted to investigate weather as a potential driver of cases and to question its ability to predict incidence. Salmonella is an important causative agent of diarrhoeal disease worldwide with an estimated 80.3 million cases annually. In Europe, Salmonella is frequently involved in foodborne outbreaks, accounting for almost one in three foodborne outbreaks. This thesis investigates the main meteorological factors associated with human salmonellosis and characterized their role in contributing to disease. The overarching objective of the thesis is to improve preparedness of salmonellosis informed from meteorological data.

description:

description: The conditional incidence model is a statistical approach to estimate the incidence of salmonellosis based on weather conditions by stratifying 17 years of historical data from England and Wales. One of the novelties of this method lies in the comprehensive exploration of the effect of 13 weather factors with high spatial-temporal linkage and stratified in different combinations. The robustness of the methodology was validated by comparing the model outcomes with reported laboratory-confirmed data, as well as its application in a different location (i.e., the Netherlands). The model was also applied to investigate the impact of eggs and chicken on disease ocurrence under different temperatures, and to assess the effect of climate change on the seasonality of salmonellosis.

description:

description: Air temperature (>10⁰C), relative humidity, precipitation (dry conditions), dewpoint temperature (7-10⁰C), and day length (12-15h) were identified as key weather factors associated with salmonellosis, irrespective of geographical location. In a future climate scenario marked by rising temperatures, this conditional incidence suggests an increase in the overall number of cases with a less marked seasonal pattern. The presented research expands our understanding of the widely accepted but under-investigated role of weather and climate in modulating disease. Additionally, this thesis contributes to generating hypotheses on the mechanisms through which weather contributes to disease, establishing a foundation for future predictive tools applicable to other environmentally-driven diseases.