cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Tetramorium quasirum Bolton, 1979, sp. n.
Creators: name: Bolton, B.
Publisher: name: Zenodo
Year: 1979
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Tetramorium
Tetramorium quasirum

description: Tetramorium quasirum sp. n.
Holotype worker. TL 2.4, HL 0.64, HW 058, CI 91, SL 040, SI 69, PW 0.42, AL 0.70.
Mandibles longitudinally striate; anterior clypeal margin with a median notch or impression. Eyes relatively small, maximum diameter 0.12, about 0.21 x HW, the eye noticeably elongate, about twice longer than broad. Frontal carinae not strongly developed, behind the level of the eyes no more strongly marked than the cephalic rugular sculpture which they merge into posteriorly. Antennal scrobes shallow and inconspicuous but less strongly sculptured than remainder of head. Propodeal spines acute, feebly upcurved along their length; metapleural lobes bluntly triangular. Petiole in profile strongly nodiform with roughly parallel, vertical anterior and posterior faces and an evenly convex dorsum, the length of the dorsum about equal to the height of the tergal portion of the node. Antero- and posterodorsal angles of the node narrowly rounded in profile and blunt. In dorsal view the node slightly longer than broad. Postpetiole evenly convex in profile. Dorsum of head closely and irregularly longitudinally rugulose with some feeble cross-meshes, and merging into a disorganized reticulum posteriorly. Spaces between the rugulae conspicuously punctulate. Dorsal alitrunk reticulate-rugulose, more strongly marked than on head, the individual rugulae low and blunt, with a beaded appearance due to aligned punctulation on their upper surfaces. Spaces between them with feeble and sparse punctulation, less strong than on head. Dorsum of petiole with feebly marked sculpture, postpetiole and gaster smooth. All dorsal surfaces of head and body with numerous fine hairs, the gaster also with conspicuous long pubescence. Colour dark brown.
Paratype workers. As holotype, some of them a lighter shade of brown. Dimensions TL 2.4 - 2.6, HL 0.62 - 0.64, HW 0.56 - 0.59, CI 90.94, SL 0.39.0.42, SI 69 - 73, PW 0.40 - 0.43, AL 0.69 - 0.72, maximum diameter of eye 0.11 - 0.12 (0.20 - 0.21 x HW) (10 measured).
Holotype worker, Madagascar: Bongolava, Pref. Tsiroanomandidy, 6 - 11. xii. 1974, forest humus and litter, series AB 48 (A. Peyrieras) (MCZ, Cambridge). Paratypes. 14 workers with same data as holotype (MCZ, Cambridge; BMNH).
NON-PARATYPIC MATERIAL
A second series consisting of 4 workers and a female bear the data Madagascar: Rte d'Anosibe, km 33, 4 - 12. iv. 1975, forest humus and litter, AB 49 (A. Peyrieras). These match the type-series well but are darker in colour, being black or nearly black.
This small species is related to ranarum but is smaller, has slightly larger eyes and much less strongly developed frontal carinae.
description: Published as part of Bolton, B., 1979, The ant tribe Tetramoriini (Hymenoptera: Formicidae). The genus Tetramorium Mayr in the Malagasy region and in the New World., pp. 129-181 in Bulletin of the British Museum (Natural History) Entomology 38 on pages 150-151
Protease activated gene transfer for local and targeted delivery to cancer cells
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Cancer gene therapy protocols are currently limited by inefficient targeting and their efficiency to toxicity ratio. We aim to improve both the targeting of cancer cells and the efficiency to toxicity ratio through local gene delivery approaches. Intratumoral administration of gene-based drugs is currently used to prevent systemic toxicity; however, even in these approaches retention of the drug in the tumor remains a challenge. We propose that the immobilization rather than the encapsulation of DNA nanoparticles inside a hydrogel scaffold will result in the retention of the drug at the desired site. Further, we propose that by controlling the release of the immobilized nanoparticles, so that release only occurs next to the target cell, targeted delivery can be achieved. We hypothesize that the immobilization of DNA nanoparticles to a hydrogel scaffold via protease degradable peptides results in localized and targeted gene transfer to cells that highly express proteases. The specific aim of this proposal is to design and evaluate a local gene delivery strategy that can target cancer cells through their protease expression profile. We will utilize the fact that matrix methalloproteinase-2 (MMP-2) is over expressed in most invasive cancers to trigger release of immobilized DNA nanoparticles. The proposed studies are divided into three aims. Aim 1 is to study the release rate of immobilized polyplexes in order to determine if the chosen peptide sequences are degradable by MMP-2 primarily. We propose to use the cationic polymer polyethylene imine to form the DNA nanoparticles and to immobilize the DNA nanoparticles to surfaces through biotin-avidin bonds (biotin will be present on the DNA nanoparticle and avidin will be immobilized on the surface). We will perform release assays in solutions containing different types of enzymes to study the specificity of the peptides to MMP-2 degradation. Aim 2 is to study if cells plated on top of immobilized DNA nanoparticles are transfected efficiently only if the cells express high levels of MMP-2. We will use green fluorescent protein and luciferase reporter genes to quantify the level of gene expression. The degree of cellular internalization of the immobilized nanoparticles will be determined using flow cytometry. Last, Aim 3 is to study the release rate of DNA nanoparticles immobilized in the bulk of a hydrogel scaffold in order to determine if we can prevent the passive diffusion of DNA nanoparticles out of the hydrogel.
Master plan, borough of Totowa, New Jersey
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1959

description: This report is the result of eighteen months of fact finding, analysis, and study on the part of the Totowa Borough Planning Board and its consultants. It outlines the major objectives and plans considered at this time as necessary for the future development of the Borough.While planning is a continuing process, it is important that goals be established and adopted by the planning board to guide it in its day to day decisions and recommendations on current problems and projects.This report is published with the hope and expectation that the citizens will give it thoughtful consideration and offer suggestions for improvement before the planning board adopts it after public hearing according to law.
General development plan for Teaneck, New Jersey
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1962

description: The proposed General Development Plan for Teaneck is long-range, comprehensive, and general.Long-range planning is necessary because physical improvements usually require considerable time to program and accomplish, especially in a community as intensively developed as Teaneck. Such improvements must take into account not only existing conditions, but future needs as well. The desired results are accomplished by the cumulative effect of day-to-day decisions related to long range goals.Comprehensive planning is necessary because all the parts of the Plan are interdependent. The functional relationships between land use, types of structures, population density and public facilities and services must be studied, understood and respected.General planning is necessary since the Plan is fundamentally a policy statement intended for use as a guide in making decisions on specific details. In order to be consistent, decisions on details must be viewed from the perspective of general policy. With the Plan looking forward to two decades, however, development policy must be kept current in order to adjust to changing conditions and unforeseen events.
A peek into focal adhesion mechanotransduction: The key initial step in cell migration and metastasis
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Cell migration and growth requires mechanical interaction with the extracellular matrix (ECM). The membrane bound molecule integrin is the main contact between the cell and the ECM. Integrin molecules bind tightly to ECM filaments transmitting any mechanical stimulation form interaction of the cell with the ECM to the interior of the cell. In order to maintain its stability, the cell attaches its actin filaments to the integrin-ECM complexes via focal adhesions, which are bundles of many molecules interacting tightly with each other, with integrin molecules, and with actin filaments. Recruitment of molecules to focal adhesions at the site of integrin molecules exposed to mechanical stimulation from the ECM occurs by mechanosensation. Molecules that alter their binding affinities and cellular function in response to the mechanical stimulation are known as mechanosensors. Talin is a key molecule in the formation of focal adhesions and the recruitment of actin to focal adhesions, and it is a mechanosensor. Talin interacts with integrin and can link to actin via the protein vinculin. We show that the interaction of talin with vinculin is regulated by mechanical force originating in the interaction between the ECM and integrin molecules. Using computational molecular dynamics simulation methods we investigate the mechanism of the four stages in the linking of actin filaments to the integrin-ECM complex: activation of talin’s cryptic vinculin binding site (VBS1), interaction of VBS1 with the vinculin head (Vh), activation of vinculin by dissociation of the vinculin tail(Vt) from Vh, and binding of Vt to two actin monomers. Our preliminary results have shown that a locally applied force to a region of talin’s rod domain containing VBS1 results in rotation in one of talin’s a-helices exposing VBS1, a hydrophobic patch, to solvent and activating it for interaction with the Vh. We have also determined that VBS1 interacts with the Vh to cause separation of two Vh helices, H1 and H2. We propose to further advance the understanding of actin recruitment to focal adhesions via mechanosensation by the talin-vinculin interaction by simulating the activation of vinculin as a result of H1 separating from H2. Through our simulations we determine the atomic scale mechanisms of these interactions and pinpoint key structural features of talin and vinculin underlying successful focal adhesion formation. The results will be especially useful for research aimed at preventing focal adhesion formation in metastasizing cancer ce
Defining meningioma stem cells: The key to developing more representative model systems
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: My research laboratory is focused on understanding the molecular genetics of meningiomas. Meningiomas are common primary brain tumors that arise in the meninges and are a considerable cause of morbidity and mortality because of their location, the existence of aggressive variants and unexpected disease recurrences. Despite being a serious clinical concern, meningiomas remain a poorly understood cancer. Experimental investigations into their biology have been hampered by the lack of appropriate model systems. Cancer stem cells (CSCs) are the subpopulation of cells within a tumor with the greatest ability to proliferate and form new tumors. They have phenotypic and functional properties similar to normal stem and progenitor cells including the ability to self-renew and the capacity to differentiate. CSCs form all the cell types found in the parent tumor when xenotransplanted into mice in vivo. Effective therapies would need to target and eliminate the CSCs within a tumor. Thus, understanding the nature of the CSC of a given tumor type is essential to understanding the biology of the tumor, to developing more representative model system and to designing novel therapies. Although meningeal-derived mesenchymal stem cells have been isolated, nothing is known about the characteristics of the putative meningioma stem cell. We hypothesize that defining the meningioma stem cell will lead to the development of in vitro and in vivo model systems that are more representative of the human disease. Our preliminary studies show that tumor spheres can be grown from dissociated primary meningioma tumors and that primary meningiomas express mesenchyme stem cell markers. The goal of this one-year proposal is to isolate and characterize meningioma stem cells from primary meningioma tumors. We will characterize their self-renewal and differentiation capabilities and assess expression of mesenchymal stem cell markers. Next, we will use this tumorigenic subpopulation of meningioma cells to develop an intracranial xenograft meningioma model in immunodeficient mice. In the long-term, this will lead to an improved understanding of meningioma tumorigenesis, and the development of novel targeted therapies.
Ariidae Bleeker 1858
Creators: name: Angulo, Arturo
name: Betts, Joel T.
name: González-Alemán, Néstor J.
name: Castañeda, Edgar
name: Berghe, Eric Van Den
name: Elías, Diego J.
name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Siluriformes
Ariidae

description: Family Ariidae Bleeker 1858 (Fig. 3F). Sea Catfishes; Bagres, Cuminates, Congos
Description: Body elongate, rounded (cylindrical) to depressed; usually less than 100 cm in length; head large, rounded to depressed; usually three pairs of barbels, rarely two (no nasal barbels); top of head covered by a rough bony shield that is partly visible through the thin skin, with a bony process that extends back to meet a bone plate at the base of the dorsal fin; pectoral and dorsal fins with a strong spine; adipose fin present; anal fin with 14–40 soft rays; caudal fin deeply forked (Robertson & Allen 2015, Nelson et al. 2016). Distribution: Mainly marine, many fresh or brackish water; worldwide, tropical to warm temperate oceans (Nelson et al. 2016). Four genera and eleven species in Nicaraguan freshwaters.
description: Published as part of Angulo, Arturo, Betts, Joel T., González-Alemán, Néstor J., Castañeda, Edgar, Berghe, Eric Van Den, Elías, Diego J., Mcmahan, Caleb D. & Matamoros, Wilfredo A., 2023, Continental fishes of Nicaragua: diversity, distribution and conservation status; with an annotated and illustrated checklist of species and an identification guide to families, pp. 1-89 in Zootaxa 5376 (1) on page 28, DOI: 10.11646/zootaxa.5376.1.1, http://zenodo.org/record/10208788
Langxie feti Tang, Jia, Liu 2023
Creators: name: Tang, Victoria
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Scorpiones
Buthidae
Langxie
Langxie feti

description: (1) Langxie feti Tang, Jia, Liu, 2023
TYPE LOCALITY AND TYPE DEPOSITORY. China, Tibet Autonomous Region, Nyingchi Prefecture, Zayü County, Golag Township; VT.
CHINESE EQUIVALENT. Ṕ氏Ṙx.
DISTRIBUTION (●). Xizang: Nyingchi City (Zayü County: Cawarong and Golag townships).
description: Published as part of Tang, Victoria, 2025, A review of scorpiofauna of China: nomenclatural notes and updated faunistic catalogue (Arachnida: Scorpiones), pp. 1-24 in Euscorpius 404 on page 15, DOI: 10.5281/zenodo.14660932
Ariopsis assimilis
Creators: name: Angulo, Arturo
name: Betts, Joel T.
name: González-Alemán, Néstor J.
name: Castañeda, Edgar
name: Berghe, Eric Van Den
name: Elías, Diego J.
name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Siluriformes
Ariidae
Ariopsis
Ariopsis assimilis

description: Ariopsis assimilis (Günther 1864). Mayan Sea Catfish; Bagre Maya
Vouchers: Not available. Distribution: Western Atlantic Ocean; from Quintana Roo, Mexico, to Costa Rica; entering estuaries and littoral lagoons and ascending river courses; (Nicaragua) WK, GM, KP, Es, BF, IM and To (Atlantic); 0–10 masl; Per, Dia, Amp. Occurrence and conservation status: Nat; LC (2019), population trend decreasing. Literature: Villa (1982: 114; detailed description, including illustrations and an identification key, and information on distribution and ecology), van den Berghe (2015: 40, as Arius seemanni —misidentification; listed, including an illustration and information on distribution and ecology), Robertson & Van Tassell (2019: 2976; detailed description, including illustrations, and information on distribution, with a map, and ecology) and Angulo (2021: 31; listed, including information on distribution).
description: Published as part of Angulo, Arturo, Betts, Joel T., González-Alemán, Néstor J., Castañeda, Edgar, Berghe, Eric Van Den, Elías, Diego J., Mcmahan, Caleb D. & Matamoros, Wilfredo A., 2023, Continental fishes of Nicaragua: diversity, distribution and conservation status; with an annotated and illustrated checklist of species and an identification guide to families, pp. 1-89 in Zootaxa 5376 (1) on page 28, DOI: 10.11646/zootaxa.5376.1.1, http://zenodo.org/record/10208788
Atlantodesmus pickeli
Creators: name: Bouzan, Rodrigo Salvador
name: Iniesta, Luiz Felipe Moretti
name: Brescovit, Antonio Domingos
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Diplopoda
Polydesmida
Chelodesmidae
Atlantodesmus
Atlantodesmus pickeli

description: Atlantodesmus pickeli (Schubart, 1946)
BRAZIL • 1 ♂; São Paulo, São Paulo, Jardim São Bento; 46°38′0″ W, 23°33′0″ S; 1939; Dom B.J. Pickel coll.; IBSP 29 • 1 ♀; same collection data; IBSP 4433.
description: Published as part of Bouzan, Rodrigo Salvador, Iniesta, Luiz Felipe Moretti & Brescovit, Antonio Domingos, 2019, Cladistic analysis and description of a new species of the Brazilian genus Atlantodesmus Hoffman, 2000 (Diplopoda: Polydesmida: Chelodesmidae), pp. 1-17 in European Journal of Taxonomy 538 on page 16, DOI: 10.5852/ejt.2019.538, http://zenodo.org/record/3346493
Design and synthesis of potent anti-cancer agents
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Background: Proteasome inhibitors are a new class of potential anti-tumor drugs. Cancer cells are especially susceptible to a proteasome inhibitor due to their unchecked growth, which demands much higher levels of proteasome to regulate those rapid cycles of protein synthesis and degradation. Objective/hypothesis: The novel chemical reagents (convertible isocyanides for Ugi/Passerini multi-component condensation reaction) developed in our group are effective to apply to the chemical total synthesis of complex bioactive natural products containing a gamma-lactam moiety. We propose the total synthesis of potent and selective 20S proteasome inhibitors omuralide and salinosporamide A and their derivatives. Specific aims: 1. Development of the versatile synthetic methodology, which allow to chemically synthesize the biologically active functional gamma-lactam derivatives with a good efficiency of chemical yield and a great diversity of the stereochemistry. 2. The Application of the developed methodology to the chemical total syntheses of the proteasome inhibitors omulalide/salinosporamide A. Study design: Our synthetic design of salinosporamide A relies on the diastereoselective construction of pyroglutamic acid core structure by using the Ugi four component condensation reaction with the novel convertible isocyanide developed in our group. The feasibility of the approach with the isocyanide was proven in the formal total synthesis of omuralide, which shares the same gamma-lactam/beta-lactone fused core framework. Cancer relevance: This proposal includes the synthetic studies on the chemical total synthesis of a potent and selective 20S proteasome inhibitors. A small marine natural product, called salinosporamide A, produced by a microorganism collected from the deep sea was proved to work as a high-performance micro-machine to attack cancer cell by selective functional loss of its specific enzyme proteasome in human body. Timescale and scope: The proposed synthesis of the potent anti-cancer agent will be achieved by the end of the duration of the grant (in one year).
Tetramorium ranarum Forel
Creators: name: Bolton, B.
Publisher: name: Zenodo
Year: 1979
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Tetramorium
Tetramorium ranarum

description: Tetramorium ranarum Forel
(Fig. 25)
Tetramorium (Xiphomyrmex) ranarum Forel, 1895 b: 486. Syntype workers, Madagascar: central Madagascar {Sikora) (MHN, Geneva) [examined].
Worker. TL 3.0 - 3.3, HL 0.72 - 0.82, HW 0.68 - 0.76, CI 94 - 97, SL 0.48 - 0.54, SI 67 - 71, PW 0.48 - 0.55 ' AL 0.80 - 0.88 (8 measured).
Mandibles strongly longitudinally striate, anterior clypeal margin with a median notch or impression. Eyes relatively small, maximum diameter c. 0.13 - 0.14, about 0.17 - 0.19 x HW. Frontal carinae strong and surmounted by a raised narrow rim or crest, occipitally becoming weaker and merging into the other cephalic sculpture. Antennal scrobes shallow but broad, the scrobal area with some rugulose sculpture. Propodeal spines elongate and strong, tending to be upcurved along their length. Metapleural lobes broadly triangular and acute. Petiole node in profile blocky, about as long dorsally as the tergal portion is high. In dorsal view the petiole node about as broad as long, in some specimens slightly broader than long and vice versa in others. Postpetiole evenly convex in profile, much broader than petiole in dorsal view. Head predominantly bluntly longitudinally rugulose with some cross-meshes and with a reticulum occipitally, the dorsal surfaces of the blunt rugulae with a beaded appearance due to the presence of aligned punctulae. Spaces between rugulae weakly punctulate. Dorsal alitrunk reticulate-rugulose, the rugulae more strongly developed than on the head but still blunt and with the same beaded appearance. Petiole dorsum with traces of rugular sculpture, the postpetiole and gaster unsculptured. All dorsal surfaces of head and body with numerous fine hairs. Colour medium to dark reddish brown.
T. quasirum and coillum are the species most closely related to ranarum, the three of them sharing a similar habitus but differing in detail. Thus, quasirum is a noticeably smaller species than ranarum with relatively larger eyes, and coillum has the petiole more sharply angulate and retains rugulose sculpture on the postpetiole.
Material examined
Madagascar: Perinet (W. L. Brown); Andasibe (= Perinet) (W. L. & D. E. Brown).
description: Published as part of Bolton, B., 1979, The ant tribe Tetramoriini (Hymenoptera: Formicidae). The genus Tetramorium Mayr in the Malagasy region and in the New World., pp. 129-181 in Bulletin of the British Museum (Natural History) Entomology 38 on page 151
A novel role for the kinase complex Bur1/2 in pre-mRNA splicing and the molecular basis of cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Pre-messenger RNA splicing, the process whereby non-coding sequences that interrupt a gene are removed from a newly-synthesized RNA molecule, is an important target of regulation. In fact, it has been estimated that at least 15% of all point mutations that lead to disease are caused by defects in pre-mRNA splicing. Furthermore, almost every known human cancer can be attributed to defects in splicing. Hence, understanding the basic mechanism of pre-mRNA splicing and its regulation are essential to understanding the mechanisms underlying splicing related disease. We have focused our studies on understanding the basic mechanisms of splicing using the genetically and biochemically tractable organism Saccharomyces cerevisiae. In work described below we have identified an unexpected role for the Bur1/2 complex, which is the yeast homologue of P-TEFb and has been well-characterized for its role in transcription elongation, in pre-messenger RNA splicing. Cells or extracts lacking a functional Bur complex exhibit a splicing defect in vivo and in vitro, indicating that this function can be uncoupled from its role in transcription. Furthermore, we demonstrate that the Bur complex phosphorylates the U2 snRNP proteins Cus2. These results lead to the hypothesis that the Bur complex, through its phosphorylation of the snRNP component, Cus2, functions in pre-mRNA splicing. To test this hypothesis we will undertake the following Specific Aims: 1. Characterize of the Bur1/2 complex function in splicing (1.1) Use in vitro spliceosome assembly assays to identify the step in splicing for which the Bur complex is required (1.2) Use known mutants of BUR to determine what function of the complex is required for its splicing activity 2. Determine if Bur phosphorylation of Cus2 is responsible for its function in splicing (2.1) Reconstitute in vitro splicing of a bur2?cus2? splicing extract to determine the role of Cus2 on the splicing defect caused by deletion of BUR2 (2.2) Map Cus2 phosphorylation sites and utilize Cus2 phospho-mutants in in vitro spliceosome assembly, in vitro splicing, and in vivo splicing
Critical Reflection on Applying Active Learning, Formative Assessment and Hidden Curriculum in the Course ‘Intermediate Microeconomics
Creators: name: Md Mazbahul Haque, Wasim
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 390102
subject: Curriculum and pedagogy theory and development

description: This investigation is intended to explore the relevance of three pertinent concepts: active learning, formative assessment and hidden curriculum in the context of student centered learning. To assess the reflection of these concepts of contemporary educational process in Bangladeshi government colleges, the course ‘Intermediate Microeconomics has been selected from the economics honors syllabus. Evaluating the students’ reflection and achievement four model lesson outlines prepared and applied in the consecutive four classes. The result was more than expected level and student engagement observed fantastic. The study outcome suggests that incorporating these three techniques in the four lesson plans makes the teaching procedure more intensive, attractive and fruitful. Here active learning, formative assessment and hidden curriculum function as complementary activities to each other. Each of the techniques has innate quality to intensify learning outcome.
General development plan: summary report
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1963

description: In this general development plan summary report for the Borough of Spring Lake Heights, the Planning Board has developed the following goals and objectives for the Borough: (1) Improving its residential character; (2) Enhancing land and property values; (3) Encouraging economically self-sustaining development; (4) Purchasing land for future facilities in advance; (5) Establishing a functional traffic system; (6) Conserving open space and planning for improved recreational and public facilities; and (&) Allowing for controlled commercial expansion.
Additional file 1: of Enhancing Mental and Physical Health of Women through Engagement and Retention (EMPOWER): a protocol for a program of research
Creators: name: Hamilton, Alison
name: Farmer, Melissa
name: Tannaz Moin
name: Finley, Erin
name: Lang, Ariel
name: Oishi, Sabine
name: Huynh, Alexis
name: Zuchowski, Jessica
name: Haskell, Sally
name: Bevanne Bean-Mayberry
Publisher: name: Figshare
Year: 2017
Subjects: subject: Neuroscience
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Individual project description: Tailoring VAâ  s Diabetes Prevention Program to Women Veteransâ   Needs (Tannaz Moin (PI) and Sally Haskell (Co-PI)). (DOCX 48Â kb)
MOESM2 of PYM: a new, affordable, image-based method using a Raspberry Pi to phenotype plant leaf area in a wide diversity of environments
Creators: name: Valle, Benoît
name: Simonneau, Thierry
name: Boulord, Romain
name: Sourd, Francis
name: Frisson, Thibault
name: Ryckewaert, Maxime
name: Hamard, Philippe
name: Brichet, Nicolas
name: Dauzat, Myriam
name: Christophe, Angélique
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Additional file 2. Detailed wiring between the contactor and Raspberry Pi computers. By default, GPIO18 is connected to Ground, when the contactor is pushed, electric power is transferred to GPIO18, launching a script in the Raspberry Pi, triggering the image capture on all connected devices. A 470 k Ω resistor was attached to the GPIO18 entry at the contactor level to reduce. The cameras are not shown in this view.
Regulation of inflammation by epidermal caspase-8
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: As one of the few organs that undergo continual renewal, the mammalian skin is a powerful tool to study the regulation of organ regeneration. Therefore, stem cells in the skin must constantly balance the need to renew itself and maintain a pool of progenitor cells with the requirement to differentiate to reconstruct a tissue that turns over every few weeks. The two basic components of the skin are an epithelial compartment and an underlying mesenchymal compartment separated by a basement membrane. The epithelial compartment is composed partly of the epidermis - a stratified structure comprised of a basal layer of proliferative stem cells (keratinocytes). Select keratinocytes cease proliferating and enter into a terminal differentiation program to form the epidermis. The resulting death of keratinocytes requires that the epidermis be constantly renewed every two weeks and thus epidermal homeostasis is achieved by regulating the delicate balance of cells in the proliferative/self-renewal state vs. those entering the terminal differentiation. Under conditions of epidermal repair, such as wound-healing, this balance shifts dramatically toward proliferation. Disregulation of this equilibrium in either direction can lead to various diseases and a molecular understanding of this balance will provide important insights on how to contend with them. In this proposal we will investigate the novel role of caspase-8 in mediating inflammation during tissue repair. We found that caspase-8, which mediates receptor-activated apoptosis, is expressed in the differentiated cells of the outer layer of the epidermis and suspected that it would play a role in the normal turnover of keratinocytes. However, a knockout mouse model shows that caspase-8 is dispensible for keratinocyte apoptosis and instead suggests that it coordinates stem cell proliferation, wound healing, keratinocyte migration and inflammation in the skin. Mutant mouse models and cultured skin stem cells will be used to: 1. Characterize the inflammatory and proliferation responses that results from the loss of caspase-8 in the epidermis and; 2. Begin to probe the signaling pathways that may link a “death protein” with inflammation.
Lychas mucronatus
Creators: name: Tang, Victoria
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Scorpiones
Buthidae
Lychas
Lychas mucronatus

description: (1) Lychas mucronatus (Fabricius, 1798)
TYPE LOCALITY AND TYPE DEPOSITORY. “ India ” (east); UZMD.
PROTONYM. Scorpio mucronatus Fabricius, 1798.
SYNONYMS. Scorpio (Androctonus) curvidigitatus Gervais, 1843; Tityus varius C. L. Koch, 1844; Isometrus chinensis Karsch, 1879 (●); Isometrus atomarius Simon, 1884; Lychas mentaweius Roewer, 1943; Lychas baldasseronii Di Caporiacco, 1947; Lychas nucifer Basu, 1964; Lychas kotao Lourenço, 2020.
CHINESE EQUIVALENT. 尖‼信使x.
DISTRIBUTION (○). Fujian; Guangxi; Guangzhou; Hainan; Taiwan; Yunnan.
description: Published as part of Tang, Victoria, 2025, A review of scorpiofauna of China: nomenclatural notes and updated faunistic catalogue (Arachnida: Scorpiones), pp. 1-24 in Euscorpius 404 on page 15, DOI: 10.5281/zenodo.14660932
Tetramorium zenatum Bolton, 1979, sp. n.
Creators: name: Bolton, B.
Publisher: name: Zenodo
Year: 1979
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Tetramorium
Tetramorium zenatum

description: Tetramorium zenatum sp. n.
(Fig. 19)
Holotype worker. TL 2.6, HL 0.64, HW 0.60, CI 94, SL 0.42, SI 70, PW 0.47, AL 0.72. Mandible coarsely longitudinally striate, anterior clypeal margin with a distinct notch or impression.
Frontal carinae strong and surmounted by a narrow rim or flange, posteriorly weaker and curving downwards around the posterior part of the scrobe, not becoming confused with the sculpture of the occipital region. Scrobes shallow but broad, bounded below by a longitudinal carina running above the eye which is upcurved posteriorly and confluent with the downcurved frontal carina. Anteriorly the scrobe divided into upper and lower portions by a feeble median carina which ends just beyond the level of the eye. Eyes with maximum diameter 0.11, about 018 x HW. Propodeal spines short and acute, the metapleural lobes elongate-triangular. Petiole in profile very distinctly shaped, see Fig. 19, the dorsum flat. In dorsal view the node about as long as broad. Dorsum of head irregularly finely rugulose, forming a reticulum occipitally. Spaces between rugulae with a punctulate ground-sculpture. Dorsal alitrunk reticulaterugulose, the dorsal surfaces of the rugulae feebly punctulate. Petiole node finely rugulose, the postpetiole and gaster unsculptured, smooth and shining. All dorsal surfaces of head and body with numerous short, fine hairs. Colour orange-brown.
Paratype worker. As holotype but teneral and without full adult colour. Slightly smaller than holotype, TL 2.5, HL 0.62, HW 0.56, CI 90, SL 0.42, SI 75, PW 0.45, AL 0.69. The eye with maximum diameter 0.10.
Holotype worker, Madagascar: Causse de Kelifely, 20 - 30. xi. 1974, forest humus and litter, dry forest AB 47 (A. Peyrieras) (MCZ, Cambridge). Paratypes. One worker and one dealate female with same data as holotype (MCZ, Cambridge; BMNH).
This species is closest related to plesiarum, both species sharing a similar strong development of the antennal scrobes, but the unique shape of the petiole node of zenatum quickly separates it from plesiarum, compare Figs 19 and 27. Also, the carina forming the lower scrobe margin is confluent with the frontal carina posteriorly in zenatum, but in plesiarum the two do not join, as indicated in Fig. 27.
description: Published as part of Bolton, B., 1979, The ant tribe Tetramoriini (Hymenoptera: Formicidae). The genus Tetramorium Mayr in the Malagasy region and in the New World., pp. 129-181 in Bulletin of the British Museum (Natural History) Entomology 38 on pages 151-152
The growth of massive galaxies and clusters at high redshift
Creators: name: Lindner, Robert Raymond
Publisher: name: No Publisher Supplied
Year: 2013

description: Massive galaxies and galaxy clusters gain much of   their mass by merging with their neighbors; this   hierarchical structure formation is the foundation of   our understanding of galaxy evolution.    Nevertheless, the detailed evolutionary  processes needed to form the structures we see in the  local Universe remain poorly understood.     This thesis comprises four projects examining the growth  of galaxies and clusters at high redshift by using radio,   sub/millimeter, and X-ray observations to   provide empirical constraints on their cosmic evolution.  Chapter 2 presents deep 1.2mm imaging   of the inner 20' x 20' of the Lockman  Hole North (LHN) field to search for submillimeter galaxies (SMGs),   rapidly star-forming, high-redshift galaxy mergers.  We detect 41 SMGs with S/N>4.0 and use Monte Carlo   simulations to estimate their number counts and angular   clustering properties.    Chapter 3 investigates the nuclear  accretion properties of the LHN SMGs.  In the sample's average rest-frame X-ray spectrum, we detect   strong Fe K alpha emission (equivalent width EW >=1 keV)   from highly-ionized Fe species --  evidence that beneath the galaxies' heavy obscuration, supermassive  black holes may be growing rapidly.  Chapter 4 describes a new 345 GHz and 2.1 GHz   imaging campaign to study the intracluster media (ICM) of   eleven massive   Sunyaev Zel'dovich Effect (SZE)-detected clusters from the   Atacama Cosmology Telescope (ACT) southern survey.  In six of eleven,  345 GHz SZE increments are detected and used   to characterize the spatial distribution and energy content of the   ICM at high (19.2") resolution.  This work helps us  understand how SZE-mass scaling relations are affected   by contamination from other sources along the line of sight  and by dynamical properties of the ICM.  Chapter 5 studies the non-thermal radio emission in   one exceptional  z=0.8&0 binary cluster merger (ACTJ0102-4915, ``El Gordo'')   with the help of newly-acquired radio observations.    El Gordo is the highest-redshift cluster known to host double radio   ``relics'' and a radio ``halo,'' and by characterizing the morphology,   intensity, spectral index, and polarization of these structures,   we extend our knowledge of  ICM shocks and magnetic fields to an era when the Universe  was only 50% its current age.
Continuous-flow hyperpolarization of 13C NMR signal of pyruvate to enable dynamic detection of tumor treatment effects through pyruvate to lactate metabolic turnover
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: We propose to hyperpolarize the 13C nuclear magnetic resonance (NMR) signal of pyruvate under ambient condition, in solution state and continuously by factors between 300-500 fold at 0.35 Tesla, employing a principle generally known as dynamic nuclear polarization (DNP). The 13C-NMR signal that we have amplified so far corresponds to polarization obtained in an imaginary >100 Tesla magnet, while 7 T is the highest field employed for in vivo magnetic resonance imaging (MRI). In a recent groundbreaking work, Golman et al. have reached even higher, ~10,000 fold, signal enhancement of 13C-pyruvate NMR signal, however by cooling the sample to 1.2 K, where polarization build-up and sample preparation time is about 3 hours per one, sub-ml, sample. The importance of monitoring pyruvate is based on the Warburg effect that states that cancerous cells show increased aerobic glycolysis of pyruvate, and thus reveal elevated lactate production compared to healthy tissues. Therefore, injection of pyruvate in vivo or in vitro to cancer cells or tissues, and monitoring its metabolic fate by NMR or MRI is directly relevant for cancer diagnosis and treatment. What makes our approach (using the Overhauser effect) unique, and also relevant from this perspective, is that we can continuously hyperpolarized pyruvate close to or at the site of intravenous or tumor tissue injection, and dynamically monitor pyruvate turnover in faster intervals, e.g. every 10 minutes, to early diagnose cancer treatment effects within hours. Another unique and important aspect of our method is that the polarization agent, the stable free radicals, are covalently bound to a gel matrix, so that the metabolic precursor to be injected is perfectly free of the toxic radicals. We expect the signal enhancement obtained with our method to be sufficiently high to be able to dynamically monitor pyruvate to lactate turnover in vivo with spatial resolution that is sufficient to localize the tumor tissue. The specific plans of this proposal include the optimization of our flow-mode DNP polarizer for stable performance, to enhance the volume of hyperpolarized pyruvate per time and to enhance the signal amplification efficiency of the spin-labeled gels. Based on our systematic studies, we have specific plans how to reach >100 Tesla worth of 13C NMR polarization of pyruvate in continuous flow. We will then demonstrate that pyruvate metabolism can be dynamically monitored in buffered solutions containing lactate dehydrogenase as well as in
Ariopsis guatemalensis
Creators: name: Angulo, Arturo
name: Betts, Joel T.
name: González-Alemán, Néstor J.
name: Castañeda, Edgar
name: Berghe, Eric Van Den
name: Elías, Diego J.
name: Mcmahan, Caleb D.
name: Matamoros, Wilfredo A.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Siluriformes
Ariidae
Ariopsis
Ariopsis guatemalensis

description: Ariopsis guatemalensis (Günther 1864). Blue Sea Catfish, Widehead Sea Catfish; Cominata Azulada, Bagre Cuatete
Vouchers: Not available. Distribution: Eastern Pacific Ocean; from southern Baja California, Mexico, to Costa Rica; entering estuaries and littoral lagoons and ascending river courses; (Nicaragua) ER, PN and Ni (Pacific); 0–11 masl; Per, Dia, Amp. Occurrence and conservation status: Nat; LC (2010), population trend unknown.
Literature: Villa (1982: 115; detailed description, including illustrations and an identification key, and information on distribution and ecology), Bussing (1998: 138; brief description, including illustrations and an identification key, and information on distribution, with a map, and ecology), Robertson & Allen (2015: 568; detailed description, including illustrations, and information on distribution, with a map, and ecology) and Angulo (2021: 31; listed, including information on distribution).
description: Published as part of Angulo, Arturo, Betts, Joel T., González-Alemán, Néstor J., Castañeda, Edgar, Berghe, Eric Van Den, Elías, Diego J., Mcmahan, Caleb D. & Matamoros, Wilfredo A., 2023, Continental fishes of Nicaragua: diversity, distribution and conservation status; with an annotated and illustrated checklist of species and an identification guide to families, pp. 1-89 in Zootaxa 5376 (1) on page 28, DOI: 10.11646/zootaxa.5376.1.1, http://zenodo.org/record/10208788
Didymoglossum hildebrandtii (Kuhn) Ebihara & Dubuisson
Creators: name: Ahamada H. Saïd
name: Sabine Hennequin
name: Germinal Rouhan
name: Jean-Yves Dubuisson
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Polypodiopsida
Hymenophyllales
Hymenophyllaceae
Didymoglossum
Didymoglossum hildebrandtii

description: Didymoglossum hildebrandtii (Kuhn) Ebihara & Dubuisson
Didymoglossum hildebrandtii (Kuhn) Ebihara & Dubuisson in Ebihara et al., Blumea 51: 236 (2006). –
Trichomanes hildebrandtii Kuhn, Von der Decken’s Reisen in Ost­Afrika in 1859 bis 1861 3(3) Botanik: 70 (1879). – Type: ‘Johanna Isl.’, s. loc., s.d., J.M. Hildebrandt 1856 (holo-: K000435634!; iso-: P00139629!).
Short description
Epiphytic; long-creeping filiform rhizomes, rootless and densely covered by dense black trichomes, bearing widely separated fronds; fronds sessile and peltate, up to 6 cm long, mostly round and entire, with false veins parallel to true veins and palmate venation; sori numerous, pantotactic, cylindrical with a truncated mouth.
Global distribution
Comoros, Madagascar.
Distribution in Comoros
Anjouan, Mayotte, Mohéli.
Additional specimens examined
COMOROS: ANJOUAN, s. loc., 1905, Lavanchie s.n. (P00139628). MAYOTTE, Massif de Mtsapéré, Maison de la Convalescence, 10 Nov. 2002, F.Rakotondrainibe et al. 6669 (P00311382). MOHÉLI, Kidogobassi, 2 Nov. 2008, M.Pignal et al. 3456 (P02439793); Au-dessus de Drondroni, 26 Mar. 2011, C.Loup et al. 590 (P02439783); Au-dessus de Drondroni, 27 Mar. 2011, E.Bidault et al. 81 (P02439772).
Note
Didymoglossum hildebrandtii is clearly distinct with round and sessile peltate fronds which seem tightly appressed against the substrate (Fig. 3C). These features, unique for the family in the region, are shared with the Pacific and Asiatic D. tahitense (Nadeaud) Ebihara & K.Iwats. to which it is evolutionary closely related (Ebihara et al. 2007).
description: Published as part of Ahamada H. Saïd, Sabine Hennequin, Germinal Rouhan & Jean-Yves Dubuisson, 2017, Disentangling the diversity and taxonomy of Hymenophyllaceae (Hymenophyllales, Polypodiidae) in the Comoros, pp. 1-53 in European Journal of Taxonomy 313 on pages 14-15, DOI: 10.5852/ejt.2017.313, http://zenodo.org/record/896401
Identity Effects in Morphological Truncation
Creators: name: Benua, Laura
Publisher: name: GLSA (Graduate Linguistic Student Association), Dept. of Linguistics, University of Massachusetts
Year: 1995

description: This study of morphological truncation establishes correspondence relations (McCarthy & Prince 1995-ROA 60) between separate words (dubbed output-output correspondence), with evidence from phonological effects of over- and underapplication. Templatic deletion and circumscriptional patterns are similarly analyzed in terms of output-output relations. Extension of the correspondence model to so-called "cyclic" phenomena is also briefly considered.
Base-Identity and Uniform Exponence: Alternatives to Cyclicity
Creators: name: Kenstowicz, Michael
Publisher: name: European Studies Research Institute, University of Salford
Year: 1995

description: This paper proposes to reinterpret cyclic effects not as input-output relations between separate levels (McCarthy & Prince 1993, Kenstowicz 1994) but rather--building on the proposals of Kraska (1995)--as similarity constraints between and among morphologically related words (cf. similar proposals independently developed by Benua 1995, Burzio 1995, McCarthy 1995, Steriade 1994, among others). In particular, a constraint of Base-Identity is proposed that evaluates candidates for a complex word [X+Y] on the basis of their similarity to the immediate constituents [X] and [Y] to the extent that the latter occur as independent outputs. In the first section we review previous approaches to cyclicity in the OT framework and propose an alternative in terms of the Base-Identity requirement between independent output forms. In the second section we discuss cases (Italian /s/-voicing, Korean cluster simplification and default accent) in which the availability of a constituent of the derivative as an independent word plays a crucial role. We then examine examples where the similarity effect is sensitive to the gross prosodic structure of the base (Palestinian Arabic, Dutch). The final section reviews similarity effects that do not fall under the rubric of identity to the base as a separate word. For these we posit a constraint of Uniform Exponence (Flemming 1995) that evaluates sets of morphologically related words for segmental and prosodic similarity. Various instances of paradigm leveling (Spanish, Swiss German, Latin, Polish) are analyzed in these terms. The paper closes with an overview of the range of observed similarity effects.