cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Grain Yield and Quality Losses Caused by Tan Spot in Wheat Cultivars in Australia
Creators: name: Cook, Melissa
name: Edwards, Jacqueline
name: Rodoni, Brendan
name: McLean, Mark S
name: Santa, Isabel Munoz
name: Hollaway, Grant J
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 310805
subject: Plant pathology
classificationCode: 3004
subject: Crop and pasture production
classificationCode: 3002
subject: Agriculture, land and farm management
classificationCode: 3108
subject: Plant biology

description: Tan spot (TS), known in Australia as yellow leaf spot, is caused by the fungal pathogen Pyrenophora tritici-repentis, a major foliar disease of wheat. Four experiments were conducted between 2016 and 2017 in two different climatic zones of southeastern Australia to determine the impact of TS on grain yield and quality in six wheat cultivars with different resistance ratings. In each experiment, high and low TS disease scenarios were applied to each cultivar. Disease severity was assessed as either whole-plot percentage leaf area affected (%LAA) or top three leaf (flag to flag-2) %LAA. Whole-plot %LAA was analyzed using both repeated measurements and area under the disease progress curve (AUDPC). For whole-plot %LAA, the repeated measurements identified differences in epidemic progression at key growth stages not identified through AUDPC. Both AUDPC and end-of-season flag to flag-2 %LAA were negatively correlated with grain yield and screenings. Increased rainfall impacting disease development and number of rain days above 5 mm increased TS severity across both climatic zones. Cultivar resistance ratings influenced grain yield loss, with moderately resistant, moderately susceptible, and susceptible cultivars losing up to 6, 18, and 24% grain yield, respectively. High disease significantly increased screenings by up to 1, 3, and 5% for moderately resistant, moderately susceptible, and susceptible cultivars, respectively. This study demonstrated that TS can cause significant grain yield losses in southeastern Australia, and a minimum cultivar rating of moderate resistance to moderate susceptibility was required to prevent severe TS and associated grain yield and quality losses. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
Myrmeleon rapax Kolbe 1897
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Myrmeleon
Myrmeleon rapax

description: Myrmeleon rapax Kolbe, 1897: 20 (Od).
 Myrmeleon (Macroleon) quinquemaculatus: Banks, 1911: 9 (Ct).
 Macroleon quinquemaculatus: Navás 1914: 16 (Ct); Navás 1923: 144 (Ct); Navás 1934: 47 (Ct).
 Distoleon quinquemaculatus: Whittington, 2002: 382 (Ct).
 Specimens examined – Somalia: 1♂, (SO.14) Togdheer, Sheikh (1440 m), 19-20.V.1988, A. Vigna Taglianti leg.
 Distribution – Widespread sub-Saharan African species (Togo east to Kenya and south to Namibia and Mozambique) including Madagascar. The species was not known from Somalia.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 49, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Moblim_Algorithm_Supplemental_Materials_as_of_08jul2020 – Supplemental material for Development of a Predictive Algorithm to Identify Adults With Mobility Limitations Using VA Health Care Administrative Data
Creators: name: Eisenberg, Yochai
name: Powell, Lisa M.
name: Zenk, Shannon N.
name: Tarlov, Elizabeth
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, Moblim_Algorithm_Supplemental_Materials_as_of_08jul2020 for Development of a Predictive Algorithm to Identify Adults With Mobility Limitations Using VA Health Care Administrative Data by Yochai Eisenberg, Lisa M. Powell, Shannon N. Zenk and Elizabeth Tarlov in Medical Care Research and Review
title: Gesundheitsfördernde Stadtentwicklung
Creators: name: Böhme, Christa
name: Köckler, Heike
name: Quilling, Eike
Publisher: name: Bundeszentrale für gesundheitliche Aufklärung (BZgA)
Year: 2023

description: Leitbegriffe der Gesundheitsförderung und Prävention. Glossar zu Konzepten, Strategien und Methoden.
Creoleon chappuisi Navas 1936
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Creoleon
Creoleon chappuisi

description: Creoleon chappuisi Navás, 1936: 112 (Od).
 Specimens examined – Somalia: 1 spec. (sex unknown), Mogadiscio, IV.1938, S. A. Nicotra leg.
 Distribution – Kenya and now Somalia.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 49, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Optimal Sparse Linear Prediction for Block-missing Multi-modality Data Without Imputation
Creators: name: Liu, Yufeng
name: Shen, Dinggang
name: Yu, Guan
name: Li, Quefeng
Publisher: name: Taylor & Francis
Year: 2019

description: In modern scientific research, data are often collected from multiple modalities. Since different modalities could provide complementary information, statistical prediction methods using multi-modality data could deliver better prediction performance than using single modality data. However, one special challenge for using multi-modality data is related to block-missing data. In practice, due to dropouts or the high cost of measures, the observations of a certain modality can be missing completely for some subjects. In this paper, we propose a new DIrect Sparse regression procedure using COvariance from Multi-modality data (DISCOM). Our proposed DISCOM method includes two steps to find the optimal linear prediction of a continuous response variable using block-missing multi-modality predictors. In the first step, rather than deleting or imputing missing data, we make use of all available information to estimate the covariance matrix of the predictors and the cross-covariance vector between the predictors and the response variable. The proposed new estimate of the covariance matrix is a linear combination of the identity matrix, the estimates of the intra-modality covariance matrix and the cross-modality covariance matrix. Flexible estimates for both the sub-Gaussian and heavy-tailed cases are considered. In the second step, based on the estimated covariance matrix and the estimated cross-covariance vector, an extended Lasso-type estimator is used to deliver a sparse estimate of the coefficients in the optimal linear prediction. The number of samples that are effectively used by DISCOM is the minimum number of samples with available observations from two modalities, which can be much larger than the number of samples with complete observations from all modalities. The effectiveness of the proposed method is demonstrated by theoretical studies, simulated examples, and a real application from the Alzheimer's Disease Neuroimaging Initiative. The comparison between DISCOM and some existing methods also indicates the advantages of our proposed method.
Supplementary_Material_ – Supplemental material for I can’t get it off my mind: Attentional bias in former and current cocaine addiction
Creators: name: Smith, Pauline
name: N’Diaye, Karim
name: Fortias, Maeva
name: Mallet, Luc
name: Vorspan, Florence
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)

description: Supplemental material, Supplementary_Material_ for I can’t get it off my mind: Attentional bias in former and current cocaine addiction by Pauline Smith, Karim N’Diaye, Maeva Fortias, Luc Mallet and Florence Vorspan in Journal of Psychopharmacology
title: Resilienz von Gemeinschaften, Städten und Gemeinwesen/Community Resilience 1 Hintergründe, Verständnis und Modelle
Creators: name: Beerlage, Irmtraud
Publisher: name: Bundeszentrale für gesundheitliche Aufklärung (BZgA)
Year: 2023

description: Leitbegriffe der Gesundheitsförderung und Prävention. Glossar zu Konzepten, Strategien und Methoden.
Supplemental_Material – Supplemental material for Constant-ductility energy factors of SDOF systems subjected to mainshock–aftershock sequences
Creators: name: Duofa Ji
name: Weiping Wen
name: Changhai Zhai
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, Supplemental_Material for Constant-ductility energy factors of SDOF systems subjected to mainshock–aftershock sequences by Duofa Ji, Weiping Wen and Changhai Zhai in Earthquake Spectra
Additional file 1 of Responsive early childhood parenting, preschool enrollment, and eventual student learning outcomes: a cross-country analysis using hierarchical linear modeling with TIMSS 2019 data
Creators: name: Bhutoria, Aditi
name: Aljabri, Nayyaf
name: Bose, Saheli
Publisher: name: figshare
Year: 2025
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 1.
Supplementary_File_011719 – Supplemental Material for Short-Term Impact of Income on Cognitive Function: Evidence From a Sample of Mexican Older Adults
Creators: name: Aguila, Emma
name: Casanova, Maria
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, Supplementary_File_011719 for Short-Term Impact of Income on Cognitive Function: Evidence From a Sample of Mexican Older Adults by Emma Aguila and Maria Casanova in Journal of Aging and Health
title: Resilienz von Gemeinschaften, Städten und Gemeinwesen/Community Resilience 2 Resilienz-Förderung
Creators: name: Beerlage, Irmtraud
Publisher: name: Bundeszentrale für gesundheitliche Aufklärung (BZgA)
Year: 2023

description: Leitbegriffe der Gesundheitsförderung und Prävention. Glossar zu Konzepten, Strategien und Methoden.
Creoleon nubifer
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Creoleon
Creoleon nubifer

description: Creoleon nubifer (Kolbe, 1897)
 Creagris nubifera Kolbe, 1897: 25 (Od); Banks, 1911: 15 (Ct).
 Creagris proximus Péringuey, 1910: 446 (Od).
 Creagris junodi Esben-Petersen, 1916: 16 (Ct).
 Gama nubifera: Banks, 1938: 7 (Tax).
 Creoleon nubifer: Esben-Petersen, 1928: 444 (Tax, Dst); Handschin & Markl, 1955: 81 (Tax, Dst).
 Specimens examined – Ethiopia: 1♀, Gemu Gofa, Arba Mintch, (ca. 1570 m), 13.XI.1973, C. Consiglio leg.; 3♀♀), idem, (ca. 1570 m), 14-15.XI.1973, A. Vigna Taglianti leg.
 Distribution – Widespread sub-Saharan Africa species including Madagascar.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 49, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
The Contribution of Shaykh Abdullah bin Foduye to Spreading Arabic Language and Islamic knowledge in Islamic Heritage
Creators: name: Tukur A.
name: Umar M.S.
Publisher: name: gjrpublication
Year: 2024

description: هذه الدراسة عبارة عن المساهمة التي قام بها الشيخ عبد الله بن فودي في انتشار اللغة العربية والعلوم الإسلامية في التراث الإسلامي. وقد حاول الباحثان من خلال الدراسة أن يبينا من هو الشيخ عبد الله بن فودي، وما هي المراحل التي مر عليها الشيخ عبد الله في أيام الطلب والأداء ، وأهم مميزات الشيخ من الناحية العلمية. كما قامت الدراسة بذكر شيوخ الشيخ ، وتلاميذه ، وإخوته ، وأبنائه ، كما انتهت الدراسة بإيراد الكتب التي ألفها الشيخ عبد الله ، وعرض موجز لأهم كتبه - رحمه الله تعالى رحمة واسعة
Additional file 1 of Strengthening the role of community health assistants in delivering primary health care: the case of maternal health services in Zambia
Creators: name: Akinola, Olatubosun
name: Banda, Nelia
name: Silumbwe, Adam
name: Mulubwa, Chama
name: Chavula, Malizgani Paul
name: Shakwelele, Hilda
name: Chila, Sylvia
name: Zulu, Joseph Mumba
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Additional file 1 of Birthing partners - validation of a questionnaire to assess the well-being of support persons
Creators: name: Schmitt, Nadine
name: Lamprecht, Juliane
name: Striebich, Sabine
name: Meyer, Gabriele
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1. English translation of the questionnaire scales and items.
Steps towards a revision of the Perla bipunctata Pictet, 1833 species complex (Plecoptera: Perlidae)
Creators: name: Reding, Jean-Paul G.
Publisher: name: Fragmenta entomologica
Year: 2023

description: The traditional view of the species Perla bipunctata Pictet, 1833 and Perla grandis Rambur, 1842 as widely distributed taxa in the West Palaearctic does not stand up to a more thoroughgoing taxonomical examination. In the present study, we demonstrate that these taxa belong to unresolved species complexes, whose members are disjunctly distributed over different, often isolated, geographical areas and mountain ranges. In the first part of this study, based upon the review of specimens labelled Perla bipunctata, Perla grandis and (obsolete) Perla maxima (Scopoli, 1763), collected by the Italian plecopterologists Elisabetta Ravizza Dematteis and Carlalberto Ravizza, between 1970 and 1994 in rivers Nure, Staffora, Stura di Demonte, Stura di Ala, Soana and Tanaro, we show, by a morphological analysis of the penial armature and the sclerotized aedeagus of adult males, that these taxa fall into three distinct groups : a taxon found in the upper course of these rivers, then a second one present in their middle section and finally a third one living only in the very low reaches. The taxonomical problems related to the identification of these three alpine taxa are discussed, and a new species, named Perla ravizzaorum, is described. This same tripartite species cluster within the Perla grandis / bipunctata species group is then shown to be replicated also in other alpine and perialpine regions, and only in these. Putative specimens of Perla bipunctata or Perla grandis collected in extra-alpine regions, such as the British-Irish Isles, the Pyrenees, the Cantabrian Cordillera, the Baetic System, and North Africa, are established as taxa belonging to different species, which are in need to be re-described and renamed. Two new species, Perla andalusiaca, from Andalusia, and Perla pyrenaica, from the Pyrenees, are described from adults and nymphs. The species name Perla carlukiana Klapálek, 1907, 1923 is re-instated for specimens from the British-Irish Isles.
description: Fragmenta entomologica, Vol. 55 No. 2 (2023)
Angursa capsula Bussau 1992
Creators: name: Fujimoto, Shinta
name: Hansen, Jesper Guldberg
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Tardigrada
Heterotardigrada
Arthrotardigrada
Styraconyxidae
Angursa
Angursa capsula

description: Angursa capsula Bussau, 1992
Fig. 5
Material examined
All three specimens were collected from a manganese nodule area off Peru, but it is not clear whether the paratypes observed in this study were collected with the holotype or at a nearby site on a different day since the museum catalogue numbers were not mentioned in the original description (Bussau 1992).
Holotype PACIFIC OCEAN • adult ♀; tropical SE Pacific, Peru Basin, collected from a manganese nodule area off Peru, 4140–4170 m deep; 07°03′84″ S, 88°28′15″ W; 17 Feb. 1989; SMF 28.
Paratypes PACIFIC OCEAN • 2 specimens collected from a manganese nodule area off Peru; SMF 29, SMF 30.
Remarks
The re-examination of the type material revealed the presence of the paired globular body fringing the mouth in the holotype (Fig. 5A), the shallow bases of the primary clavae and the lateral cirri which we do not regard as pedestals, and the morphology of the leg IV sensory organs (Fig. 5B) to be not significantly different from those of A. abyssalis and A. clavifera (Renaud-Mornant 1981; Noda 1985). The third point is especially important as its “capsule-shaped” leg IV sensory organ has been the primary diagnostic character for this species (Bussau 1992). The seconday and tertiary clavae were now very difficult to observe in the holotype. They were observed in SMF 29, but their complete contours were difficult to recognize.
description: Published as part of Fujimoto, Shinta & Hansen, Jesper Guldberg, 2019, Revision of Angursa (Arthrotardigrada: Styraconyxidae) with the description of a new species from Japan, pp. 1-19 in European Journal of Taxonomy 510 on page 8, DOI: 10.5852/ejt.2019.510, http://zenodo.org/record/2616378
Additional file 2 of Strengthening the role of community health assistants in delivering primary health care: the case of maternal health services in Zambia
Creators: name: Akinola, Olatubosun
name: Banda, Nelia
name: Silumbwe, Adam
name: Mulubwa, Chama
name: Chavula, Malizgani Paul
name: Shakwelele, Hilda
name: Chila, Sylvia
name: Zulu, Joseph Mumba
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 2
Optimization of a synthetic receptor for dimethyllysine using a biphenyl-2,6-dicarboxylic acid scaffold: insights into selective recognition of hydrophilic guests in water
Creators: name: Gober, Isaiah N.
name: Waters, Marcey L.
Publisher: name: Royal Society of Chemistry (RSC)
Year: 2017

description: In the design of small molecule receptors for polar guests, much inspiration has been taken from proteins that have adapted effective ways to selectively bind polar molecules in aqueous environments. Nonetheless, molecular recognition of hydrophilic guests in water by synthetic receptors remains a challenging task. Here we report a new synthetic receptor, A2I, with improved affinity and selectivity for a biologically important polar guest, dimethyllysine (Kme2). A2I was prepared via redesign of a small molecule receptor (A2B) that preferentially binds trimethyllysine (Kme3) using dynamic combinatorial chemistry (DCC). We designed a new biphenyl-2,6-dicarboxylate monomer, I, with the goal of creating a buried salt bridge with Kme2 inside a synthetic receptor. Indeed, incorporation of I into the receptor A2I resulted in a receptor with 32-fold enhancement in binding affinity, which represents the highest affinity receptor for Kme2 in the context of a peptide to date and is tighter than most Kme2 reader proteins. It also exhibits a ~2.5-fold increase in preference for Kme2 vs. Kme3 relative to the parent receptor, A2B. This work provides insight into effective strategies for binding hydrophilic, cationic guests in water and is an encouraging result toward a synthetic receptor that selectively binds Kme2 over other methylation states of lysine.
Ganguilus pulchellus
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Ganguilus
Ganguilus pulchellus

description: Ganguilus pulchellus (Banks, 1911)
 Macronemurus pulchellus Banks, 1911: 26 (Od).
 Nelees princeps Navás, 1936: 106 (Od).
 Ganguilus pulchellus: Michel & Mansell, 2010: 10 (Rd, Tax, Dst).
 Specimens examined – Somalia: 3♂♂, (SO.14) Togdheer, Sheikh Pass (1450 m), 19.V.1988, G. Carpaneto leg.
 Distribution – The species is known from the Horn of Africa (Eritrea, Ethiopia, Somalia, Kenya), Saudi Arabia and Pakistan.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 50, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Oxidative Addition of a Phosphinite P-O Bond at Nickel
Creators: name: Chen, Chun-Hsing
name: Miller, Alexander J. M.
name: McMillion, Noah D.
name: Bruch, Quinton J.
Publisher: name: American Chemical Society (ACS)
Year: 2023

description: Oxidative addition is an essential elementary reaction in organometallic chemistry and catalysis. While a diverse array of oxidative addition reactions has been reported to date, examples of P-O bond activation are surprisingly rare. Herein, we report the ligand-templated oxidative addition of a phosphinite P-O bond in the diphosphinito aniline compound HN(2-OPiPr2-3,5-tBu-C6H2)2 [H(P2ONO)] at Ni0 to form (PONO)Ni(HPiPr2) after proton rearrangement. Notably, the P-O cleavage occurs selectively over an amine N-H bond activation. Additionally, the ligand cannibalization is reversible, as addition of XPR2 (X = Cl, Br; R = iPr, Cy) to (PONO)Ni(HPiPr2) readily produces either symmetric or unsymmetric (P2ONO)NiX species and free HPiPr2. Finally, the mechanisms of both the initial P-O bond cleavage and its subsequent reconstruction are investigated to provide further insight into how to target P-O bond activation.
Macronemurus perlatus
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Macronemurus
Macronemurus perlatus

description: Macronemurus perlatus (Gerstaecker, 1885)
 Formicaleo perlatus Gerstaecker, 1885: 14 (Od). Macronemurus ianthe Banks, 1911: 25 (Od).
 Formicaleo neavinus Navás, 1913: 491 (Od); Tauber et al., 2019: 92 (Tax).
 Formicaleo fictus Navás, 1913: 270 (Od).
 Macronemurus nuncius Navás, 1913: 270 (Od). Macronemurus wittei Navás, 1932: 272 (Od). Macronemurus perlatus: Ábrahám & Giacomino, 2020: 56 (Tax, Dst).
 Specimens examined – Somalia: 2♂♂, 1♀, (SO.14) Togdheer, Sheikh Pass (1450 m), 19.V.1988, G. Carpaneto leg.; 4♂♂, 2♀♀, (SO.14) Togdheer, Sheikh (1440 m), 19-20.V.1988, A.Vigna Taglianti leg.; 3♂♂, idem, M. Bologna leg.
 Distribution – Angola, Democratic Republic of the Congo, Ethiopia, Kenya, Mozambique, Namibia, South Africa, Swaziland, Tanzania, Uganda, Zambia, Zimbabwe. These records extend the range to Somalia.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 50, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Otumba quadrata Hancock 1907
Creators: name: Cadena-Castañeda, Oscar J.
name: Quintana-Arias, Ronald Fernando
name: Infante, Ivette Coque
name: Silva, Daniela Santos Martins
name: Tavares, Gustavo Costa
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Otumba
Otumba quadrata

description: Otumba quadrata Hancock, 1907
(Figs. 105–106)
Otumba quadrata Hancock, 1907: 235. Lectotype, here designated. Male. ECUADOR, Cachabi, xii data. 96, Rosenberg. Code: 1903 9268. Type Orth: 120 4/5. Depository: UMO.
Remarks. This species has five syntype specimens deposited at UMO Oxford (three males and two females). The male with the labels “Cachabi, Ecuador, xii data. 96, Rosenberg. Code: 1903 9268. Type Orth: 120 4/5” is selected as a lectotype (Fig. 105). The rest are considered paralectotypes: female, with the same data as lectotype, differing: code: 1903 9533. Type Orth: 120 1/5; female code: 1903 9534. Type Orth: 120 2/5 (Fig. 106); male, code: 1903 9264. Type Orth: 120 3/5. An additional parallelectotype, a male specimen in poor condition, labeled “co-type, code: 1903 9260. Type Orth: 120 5/5,” does not belong to this species. It is a male of Allotettix or a close genus. The specimen photographed by J. Tumbrinck from Costa Rica and uploaded to OSF also does not correspond to this species, so the presence of this species in Central America is ruled out.
description: Published as part of Cadena-Castañeda, Oscar J., Quintana-Arias, Ronald Fernando, Infante, Ivette Coque, Silva, Daniela Santos Martins & Tavares, Gustavo Costa, 2025, Studies on pygmy grasshoppers: On the current Metrodorinae sensu lato classification (Orthoptera: Tetrigidae) with emphasis on American and Malagasy taxa, pp. 1-265 in Zootaxa 5597 (1) on page 157, DOI: 10.11646/zootaxa.5597.1.1, http://zenodo.org/record/14966503
Neuroleon virgineus Hoelzel 1983
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Neuroleon
Neuroleon virgineus

description: Neuroleon virgineus Hoelzel, 1983: 224 (Od).
 Specimens examined – Eritrea: 1 spec. (sex unknown), Cam Ceua, III.1940, Calcagno leg.
 Distribution – This species was known for Saudi Arabia and now this record extend the range to Eritrea.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 50, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Otumba scapularis Morse 1900
Creators: name: Cadena-Castañeda, Oscar J.
name: Quintana-Arias, Ronald Fernando
name: Infante, Ivette Coque
name: Silva, Daniela Santos Martins
name: Tavares, Gustavo Costa
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Otumba
Otumba scapularis

description: Otumba scapularis Morse, 1900
(Figs. 103, 104)
Otumba scapularis Morse, 1900: 7. Holotype: female. NICARAGUA, Río San Juan, Greytown [San Juan del Norte] (Fig. 103). Depository: ANSP.
Scabrotettix biolleyi Bolívar, 1909: 401. Holotype: female. COSTA RICA: Alajuela: Alajuela: Sarapiqui, Cariblanco (Fig. 104). Depository: MHNG. Syn. nov.
Remarks. Here, Scabrotettix biolleyi is synonymized under Otumba scapularis Morse, 1900. The type specimens of both species are females, and no differences are found that allow the two species to be kept as distinct entities, maintaining similarity in the characters of the head, pronotum, and terminalia. Additionally, Scabrotettix biolleyi is the only species of Scabrotettix that is distributed in Central America (Costa Rica), near the type locality of O. scapularis.
description: Published as part of Cadena-Castañeda, Oscar J., Quintana-Arias, Ronald Fernando, Infante, Ivette Coque, Silva, Daniela Santos Martins & Tavares, Gustavo Costa, 2025, Studies on pygmy grasshoppers: On the current Metrodorinae sensu lato classification (Orthoptera: Tetrigidae) with emphasis on American and Malagasy taxa, pp. 1-265 in Zootaxa 5597 (1) on page 157, DOI: 10.11646/zootaxa.5597.1.1
Additional file 3 of Strengthening the role of community health assistants in delivering primary health care: the case of maternal health services in Zambia
Creators: name: Akinola, Olatubosun
name: Banda, Nelia
name: Silumbwe, Adam
name: Mulubwa, Chama
name: Chavula, Malizgani Paul
name: Shakwelele, Hilda
name: Chila, Sylvia
name: Zulu, Joseph Mumba
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 3
Briley_OpenPracticesDisclosure_rev – Supplemental material for National Gross Domestic Product, Science Interest, and Science Achievement: A Direct Replication and Extension of the Tucker-Drob, Cheung, and Briley (2014) Study
Creators: name: Anqing Zheng
name: Tucker-Drob, Elliot M.
name: Briley, Daniel A.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, Briley_OpenPracticesDisclosure_rev for National Gross Domestic Product, Science Interest, and Science Achievement: A Direct Replication and Extension of the Tucker-Drob, Cheung, and Briley (2014) Study by Anqing Zheng, Elliot M. Tucker-Drob and Daniel A. Briley in Psychological Science
Radical bound for Zaremba's conjecture
Creators: name: Shulga, Nikita
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 49
subject: Mathematical sciences
classificationCode: 4901
subject: Applied mathematics
classificationCode: 4904
subject: Pure mathematics

description: Famous Zaremba's conjecture (1971) states that for each positive integer (Formula presented.), there exists a positive integer (Formula presented.), coprime to (Formula presented.), such that if you expand a fraction (Formula presented.) into a continued fraction (Formula presented.), all of the coefficients (Formula presented.) ’s are bounded by some absolute constant (Formula presented.), independent of (Formula presented.). Zaremba conjectured that this should hold for (Formula presented.). In 1986, Niederreiter proved Zaremba's conjecture for numbers of the form (Formula presented.) with (Formula presented.) and for (Formula presented.) with (Formula presented.). In this paper, we prove that for each number (Formula presented.), there exists (Formula presented.), coprime to (Formula presented.), such that all of the partial quotients in the continued fraction of (Formula presented.) are bounded by (Formula presented.), where (Formula presented.) is the radical of an integer number, that is, the product of all distinct prime numbers dividing (Formula presented.). In particular, this means that Zaremba's conjecture holds for numbers (Formula presented.) of the form (Formula presented.) with (Formula presented.), generalizing Neiderreiter's result. Our result also improves upon the recent result by Moshchevitin, Murphy and Shkredov on numbers of the form (Formula presented.), where (Formula presented.) is an arbitrary prime and (Formula presented.) is sufficiently large.
Cueta mysteriosa
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Cueta
Cueta mysteriosa

description: Cueta mysteriosa (Gerstaecker, 1894)
 Myrmeleon mysteriosus Gerstaecker, 1894:141 (Od); Kolbe, 1897: 19 (Rd).
 Nesoleon mysteriosus: Banks, 1911: 8 (Dst).
 Cueta mysteriosa: Navás, 1914: 17 (Ct.); Navás, 1935: 52 (Ct).
 Specimens examined – Ethiopia: 1♂, Gemu Gofa (loc. 54), Arba Mintch (ca. 1570 m), 13.XI.1973, C. Consiglio leg.; 4♀♀, idem, 14-15.XI.1973, A. Vigna Taglianti leg.; 1♀, Sidamo (loc. 60), 40 km W of Iavello (ca. 1500 m), 17.XI.1973, A. Vigna Taglianti leg. – Somalia: 1 spec. (sex unknown), Mogadiscio, IV.1938, S. A. Nicotra leg.; 1♀, (SO.14) Togdheer, Sheikh Pass (1450 m), 19. V.1988, G. Carpaneto leg.; 1♂, 3♀♀, (SO.02) Lower Shabelle, Afgooye, Lafoole (Facoltà di Agraria), 7-12. V.1988, A. Vigna Taglianti leg.; 2♂♂, 2♀♀, (SO.14) Togdheer, Sheikh (1440 m), 19-20. V.1988, A. Vigna Taglianti. leg.
 Distribution – The species is recorded for the Democratic Republic of Congo, Kenya, Mozambique, Somalia, Tanzania, Uganda, and South Africa. Ethiopia has now been added to these records.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on pages 50-51, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Angursa lingua Bussau 1992
Creators: name: Fujimoto, Shinta
name: Hansen, Jesper Guldberg
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Tardigrada
Heterotardigrada
Arthrotardigrada
Styraconyxidae
Angursa
Angursa lingua

description: Angursa lingua Bussau, 1992
Material examined
Out of the 19 specimens designated as type material (Bussau 1992), paratypes SMF 34, SMF 38, SMF 39, SMF 42, and SMF 43 were observed. However, the mounting media were dried out in SMF 34, SMF 38, SMF 39 and SMF 42. Due to the same problem discussed for A. capsula, the collection locality of each specimen is not clear.
Remarks
No new information was obtained from the detailed observation of SMF 43.
description: Published as part of Fujimoto, Shinta & Hansen, Jesper Guldberg, 2019, Revision of Angursa (Arthrotardigrada: Styraconyxidae) with the description of a new species from Japan, pp. 1-19 in European Journal of Taxonomy 510 on page 9, DOI: 10.5852/ejt.2019.510, http://zenodo.org/record/2616378
Parent-Child Emotion Dynamics in Families Presenting for Behavioral Parent Training: Is There a Link With Child Behavior, Parenting, and Treatment Outcome?
Creators: name: Fischer, Melanie S.
name: Highlander, April
name: Cain, Grace H.
name: Forehand, Rex
name: Loiselle, Raelyn
name: Jones, Deborah J.
name: Weber, Danielle M.
name: McCall, Madison P.
Publisher: name: American Psychological Association (APA)
Year: 2024

description: OBJECTIVE: Behavioral parent training (BPT) is the standard of care for early onset behavior disorders (BDs), however, not all families benefit. Emotion regulation (ER) is one potential mechanism underlying BPT outcomes, yet there are challenges in capturing intra- and interpersonal aspects of emotion regulation within parent-child interactions that are central to BPT. This study examined how vocally encoded emotional arousal unfolds during parent-child interactions and how parents and children influence each other's arousal (Aim 1), the links between these emotion dynamics, child behavior, and parenting at baseline (Aim 2), and BPT outcome (Aim 3). METHOD: Families of children with BDs (N = 45) completed two interaction tasks and measures of parenting and child behavior. Parent-child dynamics of vocal fundamental frequency (f‚€) were modeled using actor-partner interdependence models (APIMs) and coupled linear oscillators (CLOs). RESULTS: When considering relative levels of f‚€ from one talk turn to the next (APIMs), parents and children showed intrapersonal regulation and synchronizing reactivity to each other's f‚€. When considering the shape of oscillations (CLOs), parents and children showed intrapersonal regulation but no reactivity. Intrapersonal regulation of f‚€ during the interaction was slowed for parents with more maladaptive parenting and children with more behavior problems at baseline. CONCLUSIONS: This preliminary characterization of f0 in families presenting for BPT provides insights into the emotion dynamics potentially underlying parenting behavior and child behavior.
Nesoleon tumidus Banks 1913
Creators: name: Insom, Emilio
name: Terzani, Fabio
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Neuroptera
Myrmeleontidae
Nesoleon
Nesoleon tumidus

description: Nesoleon tumidus Banks, 1913: 156 (Od).
 Nesoleon tumidus: Esben-Petersen, 1928: 444 (Dst). Cueta tumida: Hölzel et al. 1999: 362 (Dst); Stange 2004: 294 (Tax, Dst).
 Specimens examined – Ethiopia: 1♂, Gemu Gofa, (loc. 54 bis) Arba Mintch (ca. 1570 m), 14.XI.1973, A. Vigna Taglianti leg. – Somalia: 1♀, (SO.02) Lower Shabelle, Afgooye, Lafoole (Facoltà di Agraria), 8. V.1988, at light, A. Vigna Taglianti leg.; 2♀♀, (SO.07) Lower Shabelle, Shabelle swamps, Abarey, Joware Lake, 14. V.1988, at light, G. Carpaneto leg.; 6♀♀, idem, 14-15. V.1988, at light, A. Vigna Taglianti leg.
 Distribution – The species was only known from Ethiopia, now these new records extend its distribution to Somalia.
description: Published as part of Insom, Emilio & Terzani, Fabio, 2024, Some Neuroptera of the Horn of Africa from the Museum of Zoology of the University of Rome " La Sapienza " (Neuroptera: Chrysopidae, Mantispidae, Ascalaphidae, Myrmeleontidae), pp. 39-52 in Fragmenta entomologica 56 (1) on page 51, DOI: 10.13133/2284-4880/1591, http://zenodo.org/record/12762987
Tetragonoderus fasciatus
Creators: name: Pandolfi, Alessandra
name: Schnepp, Kyle E.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Carabidae
Tetragonoderus
Tetragonoderus fasciatus

description: Tetragonoderus fasciatus (Haldeman, 1843)
(Fig. 1 a-b; GBIF Occurrence Download https://doi. org/10.15468/dl.hnymxq)
 South Dakota: Clay: iNaturalist observations 149008159; 83409895; 87841289; 87840272; BugGuide observation 2202853.
 Distribution. Alabama, Arkansas, Arizona, California, Connecticut, District of Columbia, Delaware, Florida, Georgia, Iowa, Illinois, Indiana, Kansas, Louisiana, Massachusetts, Mayland, Maine, Michigan, Minnesota, Missouri, Mississippi, North Carolina, Nebraska, New Hampshire, New Jersey, New York, Ohio, Oklahoma, Pennsylvania, South Carolina, Tennessee, Texas, Virginia, Vermont, Wisconsin, new for South Dakota.
description: Published as part of Pandolfi, Alessandra & Schnepp, Kyle E., 2024, New distributional records of the genus Tetragonoderus Dejean, 1829 from the United States of America, including an updated key to species (Coleoptera: Carabidae), pp. 65-72 in Fragmenta entomologica 56 (1) on page 66, DOI: 10.13133/2284-4880/1573, http://zenodo.org/record/12763041
Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20
Creators: name: Bodrug, Tatyana
name: Paulo, Joao A.
name: King, Randall W.
name: Sackton, Katharine L.
name: Yamaguchi, Masaya
name: Richeson, Katherine V.
name: Brown, Nicholas G.
name: Schulman, Brenda A.
name: Gygi, Steven P.
Publisher: name: Springer Nature
Year: 2020

description: The anaphase-promoting complex/cyclosome (APC/C) is a ubiquitin ligase that initiates anaphase and mitotic exit. APC/C is activated by Cdc20 and inhibited by the mitotic checkpoint complex (MCC), which delays mitotic exit when the spindle assembly checkpoint (SAC) is activated. We previously identified apcin as a small molecule ligand of Cdc20 that inhibits APC/CCdc20 and prolongs mitosis. Here we find that apcin paradoxically shortens mitosis when SAC activity is high. These opposing effects of apcin arise from targeting of a common binding site in Cdc20 required for both substrate ubiquitination and MCC-dependent APC/C inhibition. Furthermore, we found that apcin cooperates with p31comet to relieve MCC-dependent inhibition of APC/C. Apcin therefore causes either net APC/C inhibition, prolonging mitosis when SAC activity is low, or net APC/C activation, shortening mitosis when SAC activity is high, demonstrating that a small molecule can produce opposing biological effects depending on regulatory context.
supplemental_material – Supplemental material for Chinese-English Speakers’ Perception of Pitch in Their Non-Tonal Language: Reinterpreting English as a Tonal-Like Language
Creators: name: Ortega-Llebaria, Marta
name: Zhaohong Wu
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, supplemental_material for Chinese-English Speakers’ Perception of Pitch in Their Non-Tonal Language: Reinterpreting English as a Tonal-Like Language by Marta Ortega-Llebaria and Zhaohong Wu in Language and Speech
Tetragonodeus intersectus
Creators: name: Pandolfi, Alessandra
name: Schnepp, Kyle E.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Carabidae
Tetragonodeus
Tetragonodeus intersectus

description: Tetragonodeus intersectus (Germar, 1824)
(Fig. 2 a-b; GBIF Occurrence Download https://doi. org/10.15468/dl.vhnr27)
 Oklahoma: Marshall: US OK Marshall Co., U. OK Biological Sta. UVL, 33.52.59.1N, 96.48.05.3W, 7 Jul 2017, M. Quinn (2, PWMC); BugGuide observation 1426676.
 Distribution: Alabama, Arkansas, Arizona, Florida, Georgia, Kentucky, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee, Texas, Virginia, new for Oklahoma.
description: Published as part of Pandolfi, Alessandra & Schnepp, Kyle E., 2024, New distributional records of the genus Tetragonoderus Dejean, 1829 from the United States of America, including an updated key to species (Coleoptera: Carabidae), pp. 65-72 in Fragmenta entomologica 56 (1) on page 67, DOI: 10.13133/2284-4880/1573, http://zenodo.org/record/12763041
Additional file 1 of New first trimester circulating angiogenic biomarkers in predicting early-onset and late-onset fetal growth restriction: a case-control study
Creators: name: Bai, Xiaoyi
name: Li, Wei
name: Ding, Wenjing
name: Chan, Oi Ka
name: Leung, Maran Bo Wah
name: Lau, So Ling
name: Sahota, Daljit Singh
name: Wang, Chi Chiu
name: Leung, Tak Yeung
Publisher: name: figshare
Year: 2025
Subjects: Biochemistry
Space Science
Medicine
Cell Biology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology

description: Supplementary Material 1
Supplemental Material, PTD878658_supp_mat - Estimating total small solute clearance in patients treated with continuous ambulatory peritoneal dialysis without urine and dialysate collection
Creators: name: Fan, Li
name: Steubl, Dominik
name: Inker, Lesley A
name: Tighiouart, Hocine
name: Simon, Andrew L
name: Foster, Meredith C
name: Karger, Amy B
name: Eckfeldt, John H
name: Li, Hongyan
name: Tang, Jiamin
name: He, Yongcheng
name: Xie, Minyan
name: Xiong, Fei
name: Li, Hongbo
name: Zhang, Hao
name: Hu, Jing
name: Liao, Yunhua
name: Ye, Xudong
name: Shafi, Tariq
name: Chen, Wei
name: Yu, Xueqing
name: Levey, Andrew S
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental Material, PTD878658_supp_mat for Estimating total small solute clearance in patients treated with continuous ambulatory peritoneal dialysis without urine and dialysate collection by Li Fan, Dominik Steubl, Lesley A Inker, Hocine Tighiouart, Andrew L Simon, Meredith C Foster, Amy B Karger, John H Eckfeldt, Hongyan Li, Jiamin Tang, Yongcheng He, Minyan Xie, Fei Xiong, Hongbo Li, Hao Zhang, Jing Hu, Yunhua Liao, Xudong Ye, Tariq Shafi, Wei Chen, Xueqing Yu and Andrew S Levey in Peritoneal Dialysis International
Supplemental Material, ICMJF_Disclosure_Form_for_Conflict_of_Interest_Form - Effect of Self-Efficacy on Quality of Life in People With Mild Cognitive Impairment and Mild Dementia: The Mediating Roles of Depression and Anxiety
Creators: name: Tonga, Johanne B.
name: Dag-Erik Eilertsen
name: Solem, Ingrid K. Ledel
name: Arnevik, Espen A.
name: Korsnes, Maria S.
name: Ulstein, Ingun D.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, ICMJF_Disclosure_Form_for_Conflict_of_Interest_Form for Effect of Self-Efficacy on Quality of Life in People With Mild Cognitive Impairment and Mild Dementia: The Mediating Roles of Depression and Anxiety by Johanne B. Tonga, Dag-Erik Eilertsen, Ingrid K. Ledel Solem, Espen A. Arnevik, Maria S. Korsnes and Ingun D. Ulstein in American Journal of Alzheimer"s Disease & Other Dementias
SJP890699_Supplemental_material – Supplemental material for Is there a link between cardiovascular mortality and economic fluctuations?
Creators: name: Dadgar, Iman
name: Norström, Thor
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, SJP890699_Supplemental_material for Is there a link between cardiovascular mortality and economic fluctuations? by Iman Dadgar and Thor Norström in Scandinavian Journal of Public Health
PEGylation for enhancing nanoparticle diffusion in mucus
Creators: name: Huckaby, Justin T.
name: Lai, Samuel K.
Publisher: name: Elsevier
Year: 2017

description: The viscoelastic mucus secretions coating exposed organs such as the lung airways and the female reproductive tract can trap and quickly eliminate not only foreign pathogens and ultrafine particles but also particle-based drug delivery systems, thus limiting sustained and targeted drug delivery at mucosal surfaces. To improve particle distribution across the mucosa and enhance delivery to the underlying epithelium, many investigators have sought to develop nanoparticles capable of readily traversing mucus. The first synthetic nanoparticles shown capable of rapidly penetrating physiological mucus secretions utilized a dense coating of polyethylene glycol (PEG) covalently grafted onto the surface of preformed polymeric nanoparticles. In the decade since, PEG has become the gold standard in engineering mucus-penetrating drug carriers for sustained and targeted drug delivery to the lungs, gastrointestinal tract, eyes, and female reproductive tract. This review summarizes the history of the development of various PEG-based mucus-penetrating particles, and highlights the key physicochemical properties of PEG coatings and PEGylation strategies to achieve muco-inert PEG coatings on nanoparticle drug carriers for improved drug and gene delivery at mucosal surfaces.