cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Production of extended-spectrum β -lactamases and the potential indirect pathogenic role of Prevotella isolates from the cystic fibrosis respiratory microbiota
Creators: name: McIlreavey, Leanne
name: Tunney, Michael M.
name: Sherrard, Laura J.
name: McGrath, Stef J.
name: Elborn, J. Stuart
name: Hatch, Joseph
name: Gilpin, Deirdre F.
name: Wolfgang, Matthew C.
name: Muhlebach, Marianne S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Extended-spectrum β-lactamase (ESBL) production and the prevalence of the β-lactamase-encoding gene blaTEM were determined in Prevotella isolates (n = 50) cultured from the respiratory tract of adults and young people with cystic fibrosis (CF). Time–kill studies were used to investigate the concept of passive antibiotic resistance and to ascertain whether a β-lactamase-positive Prevotella isolate can protect a recognised CF pathogen from the action of ceftazidime in vitro. The results indicated that approximately three-quarters (38/50; 76%) of Prevotella isolates produced ESBLs. Isolates positive for ESBL production had higher minimum inhibitory concentrations (MICs) of β-lactam antibiotics compared with isolates negative for production of ESBLs (P < 0.001). The blaTEM gene was detected more frequently in CF Prevotella isolates from paediatric patients compared with isolates from adults (P = 0.002), with sequence analysis demonstrating that 21/22 (95%) partial blaTEM genes detected were identical to blaTEM-116. Furthermore, a β-lactamase-positive Prevotella isolate protected Pseudomonas aeruginosa from the antimicrobial effects of ceftazidime (P = 0.03). Prevotella isolated from the CF respiratory microbiota produce ESBLs and may influence the pathogenesis of chronic lung infection via indirect methods, including shielding recognised pathogens from the action of ceftazidime.
Identifying the nursing barriers to pain control in oncology patients
Creators: name: Hamdan, Maryam
Publisher: name: No Publisher Supplied
Year: 2022

description: Purpose: Inadequate pain management in the hospital setting can be attributed to various factors such as nurses’ knowledge, attitudes, and perceived barriers to pain control. Pain is one of the most significant ailments that cancer patients suffer from. Proper interventions need to be implemented to ensure the best quality of care. Nurses play a significant role in managing pain control and providing adequate pain management. The purpose of this study is to provide an educational module that addresses nurses’ knowledge, attitudes, and potential obstacles to adequate pain control to impact the assessment and treatment of cancer pain management by oncology nurses. Methodology: This Quasi-experimental quantitative research improvement project used electronic surveys to assess the impact of an educational program on oncology nurses’ knowledge, attitudes, and perceived barriers to adequate pain control in the oncology population. Results: A total of 11 participants completed the pretest, posttest, and posttest 2. The participants had an average score of 68.5% (SD=5.50) and after the educational module, the scores increased to 77.6% (SD=7.50). The results showed that while the p-value is .203, the scores still did increase from pretest to posttest 2. Inadequate pain assessment and knowledge on pain control, patients’ reluctance to report pain, and inadequate staffing were the most barriers identified. Implications for Practice: Nurses’ knowledge and attitudes toward adequate pain management are essential in providing optimal care to the oncology population. Educational interventions and the creation of evidenced-based guidelines should be implemented to prevent inadequate pain control. Identifying the barriers to inadequate pain control at an institutional level will aid each facility to intervention and therefore facilitate improved health outcomes and better quality of care.
Intermittent chaotic chimeras for coupled rotators
Creators: name: Olmi, Simona
name: Martens, Erik A.
name: Thutupalli, Shashi
name: Torcini, Alessandro
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Two symmetrically coupled populations of N oscillators with inertia $m$ display chaotic solutions with broken symmetry similar to experimental observations with mechanical pendula. In particular, we report the first evidence of intermittent chaotic chimeras, where one population is synchronized and the other jumps erratically between laminar and turbulent phases. These states have finite life-times diverging as a power-law with N and m. Lyapunov analyses reveal chaotic properties in quantitative agreement with theoretical predictions for globally coupled dissipative systems.
description: 6 pages, 5 figures SUbmitted to Physical Review E, as Rapid Communication
MPEC 2023-Q116 : 2021 GU7
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Polaronic-Quasiparticle Picture for Generation Dynamics of Coherent Phonons in Semiconductors: Transient and Non-Linear Fano Resonance
Creators: name: Watanabe, Yohei
name: Hino, Ken-ichi
name: Hase, Muneaki
name: Maeshima, Nobuya
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We examine generation dynamics of coherent phonons (CPs) in both of polar and non-polar semiconductors -- such as GaAs and Si -- based on a polaronic-quasiparticle (PQ) model. In the model concerned, the PQ operator is composed of two kinds of operators. One is a quasiboson operator -- defined as a linear combination of a set of pairs of electron operators -- and the other is a longitudinal optical (LO) phonon operator. The problem of transient and non-linear Fano resonance (FR) is tackled in particular; the vestige of this quantum interference effect was observed exclusively in lightly $n$-doped Si immediately after carriers were excited by an ultrashort pulse-laser [M. Hase et. al., Nature 426, 51 (2003)], though not observed yet in GaAs. It is shown that the phonon energy state is embedded in a continuum state formed by a set of adiabatic eigenstates of the quasiboson. This result implies the possibility of manifestation of the transient FR in the present optically-non-linear system.
description: 28 pages, 13 figures
Respiratory sinus arrhythmia and heart period in infancy as correlates of later oppositional defiant and callous-unemotional behaviors
Creators: name: Propper, Cathi
name: Rehder, Peter
name: Willoughby, Michael
name: Wagner, Nicholas
name: Mills-Koonce, Roger
name: Gueron-Sela, Noa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Extant literature suggests that oppositional defiant (ODD) and callous-unemotional (CU) behaviors in childhood and adolescence are associated with distinct patterns of psychophysiological functioning and that individual differences in these patterns have implications for developmental pathways to disorder. Very little is known about the associations between psychophysiological functioning in infancy and later ODD and CU behaviors. This study examined associations between basal autonomic nervous system (ANS) functioning in infancy and ODD and CU behaviors in later childhood. Using longitudinal heart period (HP) and respiratory sinus arrhythmia (RSA) data from the Durham Child Health and Development Study (N = 206), the current study tested associations, within a structural equation modeling framework, between continuous measures of HP and RSA across the first two years of life and later ODD and CU behaviors at first grade. Results indicate that ODD and CU behaviors in childhood are associated with lower baseline RSA, but not HP, across infancy. The implications of these findings for developmental models of ODD and CU behaviors are discussed.
Additional file 1 of Evaluation of cultural competency in a South African cluster randomised controlled trial: lessons learned for trial reporting standards
Creators: name: Siegfried, Nandi Louise
name: Hopewell, Sally
name: Erasmus-Claassen, Lesley-Ann
name: Myers, Bronwyn
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Developmental Biology
Cancer
Science Policy

description: Additional file 1: Supplementary Table S1a. Guide to Publication reporting rating. Supplementary Table S1b. Source and procedural data to be searched and scrutinised for further data. Supplementary Table S1c. Matrix of Gibbs score and publication reporting to determine data scrutiny.
Distinct Magnetic Phases in Structurally Uniform SrCoO$_{3-y}$
Creators: name: Zhu, Z. H.
name: Rueckert, F. J.
name: Budnick, J. I.
name: Hines, W. A.
name: Niedermayer, Ch.
name: Keller, L.
name: Luetkens, H.
name: Dabrowski, B.
name: Kolesnik, S.
name: Wells, B. O.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Two magnetic phase transitions have been noted for SrCoO$_{3-y}$ for near-stoichiometric oxygen concentrations (small y). Using muon spin rotation and neutron scattering experiments, we have established that the two transitions represent separate, spatially distinct magnetic phases that coexist in a two-phase equilibrium mixture. The two phases most likely represent areas of the sample with different effective valence charge density. Further, the phases exist over regions with a length scale intermediate between nanoscale charge inhomogeneity and systems such as manganites or super-oxygenated cuprates with large length scale phase separation.
description: 5 pages, 4 figures
Charged-current quasielastic scattering of muon antineutrino and neutrino in the MINERvA experiment
Creators: name: Ankowski, Artur M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: One of the largest sources of systematic uncertainties in ongoing neutrino-oscillation measurements is the description of nuclear effects. Its considerable reduction is expected thanks to the dedicated studies of (anti)neutrino-nucleus interactions in the MINERvA experiment. In this article, the calculations within the spectral function approach are compared to the charged-current quasielastic cross sections reported from MINERvA. The obtained results show that the effect of final-state interactions on the (anti)muon kinematics plays pivotal role in reproducing the experimental data.
description: 3 pages, 2 figures
Validity and reliability of the semi-quantitative self-report Home Food Availability Inventory Checklist (HFAI-C) in White and South Asian populations
Creators: name: Stevens, June
name: Bryant, Maria
name: LeCroy, Madison
name: Cai, Jianwen
name: Sahota, Pinki
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Abstract Background Despite interest in the importance of the home food environment and its potential influence on children’s diets and social norms, there remain few self-report checklist methods that have been validated against the gold standard of researcher-conducted inventories. This study aimed to assess the criterion validity and reliability of the ‘Home Food Availability Inventory Checklist’ (HFAI-C), a 39-item checklist including categories of fruit, vegetables, snacks and drinks. Methods The HFAI-C was completed by 97 participants of White and Pakistani origin in the UK. Validity was determined by comparing participant-reported HFAI-C responses to data from researcher observations of home food availability using PABAK and weighted kappa statistics. The validity of measuring the amount of items (in addition to presence/absence) available was also determined. Test-retest reliability compared repeated administrations of the HFAI-C using intra-class correlation coefficients. Results Validity and reliability was fair to moderate overall. For validity, the average category-level PABAK ranged from 0.31 (95 % CI: 0.25, 0.37) for vegetables to 0.44 (95 % CI: 0.40, 0.49) for fruits. Assessment of the presence/absence of items demonstrated higher validity compared to quantity measurements. Reliability was increased when the HFAI-C was repeated close to the time of the first administration. For example, ICCs for reliability of the measurement of fruits were 0.52 (95 %CI: 0.47, 0.56) if re-administered within 5 months, 0.58 (95 % CI: 0.51, 0.64) within 30 days and 0.97 (95 %CI: 0.94, 1.00) if re-administered on the same day. Conclusions Overall, the HFAI-C demonstrated fair to moderate validity and reliability in a population of White and South Asian participants. This evaluation is consistent with previous work on other checklists in less diverse, more affluent populations. Our research supports the use of the HFAI-C as a useful, albeit imperfect, representation of researcher-conducted inventories. The feasibility of collecting information using the HFAI-C in large, multi-ethnic samples can facilitate examination of home food availability in relation to exposures such as ethnicity and outcomes including behavioural, social and health outcomes. Future work using the HFAI-C could provide important insights into a modifiable influence with potential to impact health.
Additional file 1 of PKD1 deficiency induces Bronchiectasis in a porcine ADPKD model
Creators: name: Wang, Runming
name: Li, Wenya
name: Dai, Haiting
name: Zhu, Mingli
name: Li, Lingyu
name: Si, Guohui
name: Bai, Yilina
name: Wu, Hanyu
name: Hu, Xiaoxiang
name: Xing, Yiming
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis
Creators: name: Li, Zengpeng
name: Cai, Jian-Chun
name: Yang, James Y.
name: Wang, Tao
name: Zheng, Zihan
name: Wei, Jie
name: Hou, Jingjing
name: Song, Dan
name: Wu, Qiao
name: Hu, Tao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: MicroRNAs are a novel class of gene regulators that function as oncogenes or tumor suppressors. In our current study, we investigated the role of miR-15a-3p and miR-16-1-3p in the regulation of Twist1 expression and EMT process. Our bioinformatics analysis suggested that on the 3' UTR of Twist1, there are two conserved miRNA recognition sites for miR-15a-3p and miR-16-1-3p respectively. Interestingly, overexpression of miR-15a-3p and miR-16-1-3p significantly suppressed the activity of luciferase reporter containing Twist1-3' UTR, reduced mRNA and protein level of EMT related genes such as TWIST1, N-cadherin, α-SMA and Fibronectin, and repressed MMP9 and MMP2 activity, as well as cell migration and invasion. Conversely, inhibition of miR-15a-3p and miR-16-1-3p significantly increased TWIST1, N-cadherin, α-SMA and Fibronectin protein expression. In addition, Twist1 co-transfection significantly ameliorated the loss of cell migration and invasion. Moreover, overexpression of miR-15a-3p and miR-16-1-3p dramatically suppressed the ability of BGC823 cells to form colonies in vitro and develop tumors in vivo in nude mice. Finally, qPCR and Western blot analysis showed that miR-15a-3p and miR-16-1-3p were significantly reduced in clinical gastric cancer tissue, whereas Twist1 mRNA and protein were significantly up-regulated, suggesting that this aberrant down-regulation of miR-15a-3p and miR-16-1-3p might be associated with the abnormal regulation of Twist1 and the EMT process in gastric cancer development. Our results help to elucidate a novel and important mechanism for the regulation of Twist1 in the development of cancer.
Fast, nanoscale addressability of nitrogen-vacancy spins via coupling to a dynamic ferromagnetic vortex
Creators: name: Wolf, Michael S.
name: Badea, Robert
name: Berezovsky, Jesse
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The core of a ferromagnetic vortex domain creates a strong, localized magnetic field which can be manipulated on nanosecond timescales, providing a platform for addressing and controlling individual nitrogen-vacancy center spins in diamond at room temperature, with nanometer-scale resolution. First, we show that the ferromagnetic vortex can be driven into proximity with a nitrogen-vacancy defect using small applied magnetic fields, inducing significant nitrogen-vacancy spin splitting. Second, we find that the magnetic field gradient produced by the vortex is sufficient to address spins separated by nanometer length scales. By applying a microwave-frequency magnetic field, we drive both the vortex and the nitrogen-vacancy spins, resulting in enhanced coherent rotation of the spin state. Finally we demonstrate that by driving the vortex on fast timescales, sequential addressing and coherent manipulation of spins is possible on $\sim100$ ns timescales.
description: 7 pages, 4 figures
Relationships between maximum temperature and heat-related illness across North Carolina, USA
Creators: name: Fuhrmann, Christopher M.
name: Sugg, Margaret M.
name: Konrad, Charles E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Heat kills more people than any other weather-related event in the USA, resulting in hundreds of fatalities each year. In North Carolina, heat-related illness accounts for over 2,000 yearly emergency department admissions. In this study, data on emergency department (ED) visits for heat-related illness (HRI) were obtained from the North Carolina Disease Event Tracking and Epidemiologic Collection Tool to identify spatiotemporal relationships between temperature and morbidity across six warm seasons (May-September) from 2007 to 2012. Spatiotemporal relationships are explored across different regions (e.g., coastal plain, rural) and demographics (e.g., gender, age) to determine the differential impact of heat stress on populations. This research reveals that most cases of HRI occur on days with climatologically normal temperatures (e.g., 31 to 35 °C); however, HRI rates increase substantially on days with abnormally high daily maximum temperatures (e.g., 31 to 38 °C). HRI ED visits decreased on days with extreme heat (e.g., greater than 38 °C), suggesting that populations are taking preventative measures during extreme heat and therefore mitigating heat-related illness.
D-JRP15-FED-AMR-WP5.13 (Results of the soil microcosm experiments regarding environmental effects on competence gene expression)_Version 2
Creators: name: Cabal Rosel, Adriana
name: Wögerbauer, Markus
name: Galazka, Sonia
name: Hassan, Marwa M.
name: Chambers, Mark A.
Publisher: name: Zenodo
Year: 2023
Subjects: FED-AMR
environmental conditions
transformation
soil microcosm

description: OHEJP Project: FED-AMR
Effect of suspension system in the lateral stability of railway freight trucks
Creators: name: Molatefi, Habibollah
name: Hecht, Markus
name: Kadivar, M. H.
Publisher: name: Technische Universität Berlin
Year: 2007
Subjects: subject: 380 Handel, Kommunikation, Verkehr
subject: freight wagon
subject: BA661
subject: BA652
subject: non-linear
subject: hunting
subject: limit cycle

description: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
description: This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
description: In the current research an empty freight wagon with BA652 and an old BA661 bogies have been modelled. Non-linear creep forces with spin moment between wheel and rail have been used and also all impacts and friction forces have been modelled. The characteristics of primary suspension systems for BA652 and an old BA661 have been evaluated by means of test. Non-linear equations of motions and kinematical constraints have been solved in time domain and limit cycles have been showed. Both primary and secondary hunting can be seen in responses of wagon. For BA652 there are non-linear and linear critical speeds and also saddle nodes but for old BA661 the situation is too critical and the system can oscillate in very low speeds.
title: Transnational Organized Crime and the Illegal Wildlife Trade Global Ties and Global Crime
Creators: name: Long, Zachariah Edward
Publisher: name: Old Dominion University Libraries
Year: 2014

description: World biodiversity is faced with many different threats in today's globalized world. One such threat is the emergence of transnational organized crime in the illegal wildlife trade. But why would transnational organized crime which is traditionally associated with such crimes like illegal drugs, weapons, and human trafficking be interested in the illegal wildlife trade? This thesis seeks to explore why transnational organized crime as a rational business actor would it be interested in participating in the illegal wildlife trade. To explore this relationship, this thesis will look at several different variables. First the economic conditions oflocals living with wildlife and how globalization affects their economic choices. Second the rise of the East Asian middle class and how their integration into the world economy along with their own culturally influenced preferences in commodities affects the illegal wildlife trade. Third is the role of corruption and limited resources how these two variables affect Law Enforcement Organizations who have to fight the illegal wildlife trade and transnational organized crime. Fourth is the how transnational organized crime is changing the illegal wildlife trade in volume and methods. Finally how globalization is used by the transnational organized crime to facilitate their operations in the illegal wildlife trade. In doing so, this thesis seeks to show that from a rational business actor perspective there are sound economic reasons for transnational organized crime to operate in the illegal wildlife trade.
Venancio Quinto Interview
Creators: name: Institute For Diversity & Civic Life
name: Department Of Religious Studies
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Religions Texas
Baby Boomers
CA - Redwood City
Catholicism
Catholics
Christians
Community
Culture
Discrimination
Family dynamics
Filipino-Americans
Immigration
Immigrants
Race
Racism
Representation
Texas
The Philippines
TX - Abilene
TX - San Antonio
US Military
Washington DC

description: This interview is with Venancio Quinto, a Filipino immigrant living in San Antonio, TX. Venancio describes his childhood in the Philippines, his immigration, and early experiences in the States. He talks about living in DC, California, and Texas, and the jobs and relationships he had in each. He describes fatherhood and his relationship with his daughter. Venancio also shares his perspectives on immigration and offers advice to future immigrants to the US.
title: Betrachtung des Steuerungsentwurfs von speicherprogrammierbaren Steuereinrichtungen
title: Die Funktion im Zentrum der Programmierung
titleType: Subtitle
Creators: name: Weger, Daniel
Publisher: name: FH CAMPUS 02 (CAMPUS 02 Fachhochschule der Wirtschaft)
Year: 2023
Subjects: subject: 629 Andere Fachrichtungen der Ingenieurwissenschaften

description: Traditionell wird das Erfahrungswissen in der Automatisierungstechnik aus Versuch und Irrtum generiert, so wird auch das Vorgehen im Entwurf von Steuerungssystemen geprägt. Die kosten- und zeitintensive Methodik eine Steuerung zu entwerfen, macht das Bedürfnis nach einer alternativen Methodik des Steuerungsentwurfs groß. Die Konzeption einer neuartigen Entwurfsmethodik, die Modellierung des Zustand-Zonen Modells (ZZM), brachte vielversprechende Behauptungen hervor. Ein ZZM sei eine vollständige und zuverlässige formale Spezifikation einer informell spezifizierten Steuervorgabe. Es gilt diese Aussage zu widerlegen oder Argumente für deren Richtigkeit zu beweisen. Die Arbeit zielt darauf ab, dem ZZM ein Modell einer vielversprechenden und bereits etablierten Modellierungs-Methodik gegenüberzustellen. Eine umfassende Analyse des Steuerungsentwurfsprozesses soll zeigen, in welcher Phase Qualität entsteht und wie diese übertragen und gesichert werden kann. Eine neu gedachte Anordnung der Qualitätsmerkmale von Software zeigt eindrucksvoll, welche Prämissen seit langem fehlinterpretiert wurden und wie sich die Realität abbildet. Die Definition zielgerichteter Fragen sichert eine korrekte Bewertung und die anschließende Gegenüberstellung der Modelle. In der Schlussbetrachtung fließen weitreichende Definitionen und Erkenntnisse aus der gesamten Arbeit mit ein.
description: Traditionally, experiential knowledge in automation engineering is generated from trial and error, and this is also how the approach to control system design is shaped. The costly and time-consuming methodology to design a control system makes the need for an alternative control system design methodology great. The conception of a novel design methodology, state-zone modeling (ZZM), produced promising claims. A ZZM, it is claimed, is a complete and reliable formal specification of an informally specified control specification. The task is to refute this statement or to prove arguments for its correctness. The work aims at contrasting the ZZM with a model of a promising and already established modeling methodology. A comprehensive analysis of the control design process shall show in which phase quality emerges and how it can be transferred and secured. A newly conceived arrangement of the quality characteristics of software impressively shows which premises have been misinterpreted for a long time and how reality is reflected. The definition of purposeful questions secures a correct evaluation and the following comparison of the models. In the conclusion, wide-ranging definitions and findings are incorporated throughout the paper.
Natividad Quinto Interview
Creators: name: Institute For Diversity & Civic Life
name: Department Of Religious Studies
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Religions Texas
Baby Boomers
Catholicism
Catholics
Christians
Culture
Culture shock
Emilio Aguinaldo College
Family dynamics
Filipino-Americans
Health
Immigrants
Immigration
Medical professionals
NY - Brooklyn
NY - Kingston
NY - New Rochelle
Texas
The Philippines
TX - Abilene
TX - San Antonio

description: This interview is with Natividad Quinto, a retired nurse and Filipina immigrant living in San Antonio, TX. Natividad talks about her happy memories of the Philippines and her decision to move to the US as an adult. She describes her career in nursing at various hospitals across the country. Natividad also shares about her involvement with the Filipino and Catholic communities in San Antonio.
Age-specific risk factor profiles of adenocarcinomas of the esophagus: A pooled analysis from the international BEACON consortium: Age-specific risk factors of esophageal adenocarcinomas
Creators: name: Whiteman, David C.
name: Xiao, Qian
name: Cook, Michael B.
name: Freedman, Neal D.
name: Murray, Liam J.
name: Liao, Linda M.
name: Ye, Weimin
name: Drahos, Jennifer
name: Anderson, Lesley A.
name: Bernstein, Leslie
name: Risch, Harvey A.
name: Wu, Anna H.
name: Ward, Mary H.
name: Kamangar, Farin
name: Vaughan, Thomas L.
name: Abnet, Christian C.
name: Gammon, Marilie D.
name: Chow, Wong-Ho
name: Brown, Linda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Esophageal (EA) and esophagogastric junction (EGJA) adenocarcinoma have been steadily increasing in frequency in younger people, however the etiology of these cancers is poorly understood. We therefore investigated associations of body- mass index (BMI), cigarette smoking, alcohol consumption, gastroesophageal reflux, and use of non-steroidal anti-inflammatory drugs (NSAIDs) in relation to age-specific risks of EA and EGJA. We pooled individual participant data from eight population-based, case-control studies within the international Barrett’s and Esophageal Adenocarcinoma Consortium (BEACON). The analysis included 1,363 EA patients, 1,472 EGJA patients, and 5,728 control participants. Multivariable logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for age-specific (<50, 50–59, 60–69, ≥70 years) cancer outcomes, as well as interactions by age. BMI, smoking status and pack-years, recurrent gastroesophageal reflux, and frequency of gastroesophageal reflux were positively associated with EA and EGJA in each age group. Early-onset EA (<50 years) had stronger associations with recurrent gastroesophageal reflux (OR=8.06, 95%CI: 4.52, 14.37; Peffect modification=0.01) and BMI (ORBMI ≥30 vs. <25=4.19, 95%CI: 2.23, 7.87; Peffect modification=0.04), relative to older age groups. In contrast, inverse associations of NSAID use were strongest in the oldest age group (≥70 years), although this apparent difference was not statistically significant. Age-specific associations with EGJA showed similar, but slightly weaker patterns and no statistically significant differences by age were observed. Our study provides evidence that associations between obesity and gastroesophageal reflux are stronger among earlier onset EA cancers.
A simulation-based decision-support system for reducing duration, cost, and environmental impacts of earthmoving operations
Creators: Pourrahimian, Elyar
Al Hattab, Malak
Ead, Rana
Labban, Ramzi Roy
AbouRizk, Simaan
Publisher: name: University of Alberta Library
Year: 2020

Earthmoving operations are equipment-intensive processes that rely heavily on the proper selection of the equipment fleet and proper scheduling of associated tasks. Early equipment planning decisions have direct implications on schedules, costs, and more importantly, the environmental performance of such operations. While traditional planning of earthmoving works is ad-hoc and based on planners’ experiences, ensuring favorable performance requires advanced analytical techniques that consider multiple variables and competing objectives. Accordingly, this study develops a discrete-event simulation-based decision-support system (DES-DSS) for selecting the optimal equipment fleet, while considering the trade-offs between time, cost, and environmental impacts. The model’s results from a case study reveal how different fleet mixes and sizes can considerably impact associated emissions, durations, and costs. The DES-DSS can aid planners in making informed decisions during early planning stages and be used as a control feedback mechanism to continuously enhance operations in real-time while reducing emissions.
Implementing early mobility protocol in the ICU
Creators: name: Polley, Izabela
Publisher: name: No Publisher Supplied
Year: 2022

description: Purpose of Project: Although research findings show that mobilizing patients in the intensive care unit (ICU) is safe and produces many benefits, patients hospitalized in the ICU still spend excessive time on bed rest. The purpose of this Quality Improvement project (QI) was to make a change in practice through modifying, implementing, and evaluating a Progressive Mobility Protocol (PMP) in a comprehensive ICU at a community hospital in Southern New Jersey.Methodology: An existing PMP was modified with specific patient screening criteria. The nursing staff at the ICU were educated about the PMP via in-person sessions and an online module. In the first two weeks of implementing the PMP, morning interdisciplinary rounds were used to promote the PMP and initiate physical therapy consults. Reports from electronic health records were reviewed to compare rates of the PMP utilization before and after this QI project. Correct utilization of the PMP was evaluated through analysis of the completion of PMP activities. Feedback on the use of the PMP was elicited from nurses via an online survey.Results: Data analysis revealed a 194% increase in the daily assessments of mobility in the two weeks after the QI project was implemented. Review and comparison of the completion of the protocol activities were inconclusive due to insufficient details included in data collection. 36% of the staff completed the online survey, and it revealed that 96.3% of respondents understood the requirements of the PMP, 85.19% reported daily use of the PMP, while only 51.85% felt they had adequate staff and resources to implement the PMP.Implications: A stepwise approach to implementing a PMP in the ICU successfully increased its daily utilization. A strong multidisciplinary approach is needed to further improve patient outcomes through early mobility activities in the ICU.
Additional file 2 of Evaluation of cultural competency in a South African cluster randomised controlled trial: lessons learned for trial reporting standards
Creators: name: Siegfried, Nandi Louise
name: Hopewell, Sally
name: Erasmus-Claassen, Lesley-Ann
name: Myers, Bronwyn
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Developmental Biology
Cancer
Science Policy

description: Additional file 2: Supplementary Table S2. Results of application of Gibbs Framework and GRIPP-2(SF) to publications from Project MIND.
Genetic variations in vitamin D-related pathways and breast cancer risk in African American women in the AMBER consortium: Vitamin D SNPs and Breast Cancer Risk in African American Women
Creators: name: Johnson, Candace S.
name: Palmer, Julie R.
name: Hu, Qiang
name: Cheng, Ting-Yuan David
name: Ruiz-Narvaez, Edward A.
name: Haddad, Stephen A.
name: Trump, Donald L.
name: Liu, Song
name: Sucheston-Campbell, Lara
name: Haiman, Christopher A.
name: Bensen, Jeannette T.
name: Yao, Song
name: Hong, Chi-Chen
name: Ambrosone, Christine B.
name: Olshan, Andrew F.
name: Zhu, Qianqian
name: Lunetta, Kathryn L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Studies of genetic variations in vitamin D-related pathways and breast cancer risk have been conducted mostly in populations of European ancestry, and only sparsely in African Americans (AA), who are known for a high prevalence of vitamin D deficiency. We analyzed 24,445 germline variants in 63 genes from vitamin D-related pathways in the African American Breast Cancer Epidemiology and Risk (AMBER) consortium, including 3,663 breast cancer cases and 4,687 controls. Odds ratios (OR) were derived from logistic regression models for overall breast cancer, by estrogen receptor (ER) status (1,983 ER positive and 1,098 ER negative), and for case-only analyses of ER status. None of the three vitamin D-related pathways were associated with breast cancer risk overall or by ER status. Gene-level analyses identified associations with risk for several genes at a nominal p ≤ 0.05, particularly for ER− breast cancer, including rs4647707 in DDB2. In case-only analyses, vitamin D metabolism and signaling pathways were associated with ER− cancer (pathway-level p = 0.02), driven by a single gene CASR (gene-level p = 0.001). The top SNP in CASR was rs112594756 (p = 7 × 10−5, gene-wide corrected p = 0.01), followed by a second signal from a nearby SNP rs6799828 (p = 1 × 10−4, corrected p = 0.03). In summary, several variants in vitamin D pathways were associated with breast cancer risk in AA women. In addition, CASR may be related to tumor ER status, supporting a role of vitamin D or calcium in modifying breast cancer phenotypes.
Implementing a sleep apnea screening tool in pregnancy
Creators: name: Rodriguez, Larisa
Publisher: name: No Publisher Supplied
Year: 2022

description: Purpose of Project: Screening for Obstructive Sleep Apnea (OSA) in pregnancy is a missing component in prenatal care. This project sought to identify pregnant patients with sleep apnea between 28 and 32 weeks gestation using the STOP-BANG questionnaire and refer them for further testing and management because there is no current practice to address sleep apnea in pregnancy at the project site. Methodology: This quality improvement initiative used the FADE model to develop the project; two women’s health nurse practitioners were recruited and received an educational module. After the educational module was completed, a chart review was done, and participants completed an evaluation survey. Outcomes of interest included the number of women screened for OSA, referrals generated for those women at risk for OSA, and the number of Healthcare Common Procedure Coding System (HCPCS) codes documented in the chart. Results: A chart review showed an increase in screening, referral, and code documentation in the prenatal chart. A McNemar test was used, showing a p-value of 0.500, indicating no difference between the number of patients that needed to be referred and those that received a referral. Implications for Practice: The project intended to implement an OSA screening tool as part of routine prenatal care. Using the STOP-BANG questionnaire to screen for OSA in pregnancy and referring patients for additional testing and treatment of the condition can become the foundation for the development of a protocol that addresses gaps in care to improve healthcare practice.
Additional file 3 of Evaluation of cultural competency in a South African cluster randomised controlled trial: lessons learned for trial reporting standards
Creators: name: Siegfried, Nandi Louise
name: Hopewell, Sally
name: Erasmus-Claassen, Lesley-Ann
name: Myers, Bronwyn
Publisher: name: figshare
Year: 2022
Subjects: Medicine
Developmental Biology
Cancer
Science Policy

description: Additional file 3: Supplementary Table S3. Comparison between the Gibbs Framework and the GRIPP-2(SF).
The stability and fates of hierarchical two-planet systems
Creators: name: Petrovich, Cristobal
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We study the dynamical stability and fates of hierarchical (in semi-major axis) two-planet systems with arbitrary eccentricities and mutual inclinations. We run a large number of long-term numerical integrations and use the Support Vector Machine algorithm to search for an empirical boundary that best separates stable systems from systems experiencing either ejections or collisions with the star. We propose the following new criterion for dynamical stability: $a_{\rm out}(1-e_{\rm out})/[a_{\rm in}(1+e_{\rm in})]>2.4\left[\max(μ_{\rm in},μ_{\rm out})\right]^{1/3}(a_{\rm out}/a_{\rm in})^{1/2}+1.15$, which should be applicable to planet-star mass ratios $μ_{\rm in},μ_{\rm out}=10^{-4}-10^{-2}$, integration times up to $10^8$ orbits of the inner planet, and mutual inclinations $\lesssim40^\circ$. Systems that do not satisfy this condition by a margin of $\gtrsim0.5$ are expected to be unstable, mostly leading to planet ejections if $μ_{\rm in}>μ_{\rm out}$, while slightly favoring collisions with the star for $μ_{\rm in}
description: 15 pages, 9 figures, to be published in the Astrophysical Journal
Nevus count associations with pigmentary phenotype, histopathological melanoma characteristics and survival from melanoma
Creators: name: Thomas, Nancy E.
name: Kanetsky, Peter A.
name: Armstrong, Bruce K.
name: Taylor, Nicholas J.
name: Busam, Klaus J.
name: Cust, Anne E.
name: From, Lynn
name: Gallagher, Richard P.
name: Begg, Colin B.
name: Rosso, Stefano
name: Gruber, Stephen B.
name: Anton-Culver, Hoda
name: Orlow, Irene
name: Zanetti, Roberto
name: Nishri, Diane E.
name: Venn, Alison J.
name: Dwyer, Terence
name: Berwick, Marianne
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Although nevus count is an established risk factor for melanoma, relationships between nevus number and patient and tumor characteristics have not been well studied and the influence of nevus count on melanoma-specific survival is equivocal. Using data from the Genes, Environment and Melanoma (GEM) study, a large population-based study of primary cutaneous melanoma, we evaluated associations between number of nevi and patient features, including sun-sensitivity summarized in a phenotypic index, and tumor characteristics. We also assessed the association of nevus count with melanoma-specific survival. Higher nevus counts were independently and positively associated with male gender and younger age at diagnosis, and they were inversely associated with lentigo maligna histology. We observed a borderline significant trend of poorer melanoma-specific survival with increasing quartile of nevus count, but little or no association between number of nevi and pigmentary phenotypic characteristics or prognostic tumor features.
Mapping the domain wall pinning landscape in ferromagnetic films
Creators: name: Badea, Robert
name: Berezovsky, Jesse
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The propagation of domain walls in a ferromagnetic film is largely determined by domain wall pinning at defects in the material. In this letter we map the effective potential landscape for domain wall pinning in Permalloy films by raster scanning a single ferromagnetic vortex and monitoring the hysteretic vortex displacement vs. applied magnetic field. The measurement is carried out using a differential magneto-optical microscopy technique which yields spatial sensitivity $\sim 10$ nm. We present a simple algorithm for extracting an effective pinning potential from the measurement of vortex displacement vs. applied field. The resulting maps of the pinning potential reveal distinct types of pinning sites, which we attribute to quasi-zero-, one-, and two-dimensional defects in the Permalloy film.
description: 8 pages, 5 figures
Additional file 1 of Association of early dexamethasone therapy with mortality in critically Ill COVID-19 patients: a French multicenter study
Creators: name: Raymond, Matthieu
name: Le Thuaut, Aurélie
name: Asfar, Pierre
name: Darreau, Cédric
name: Reizine, Florian
name: Colin, Gwenhaël
name: Dano, Charly
name: Lorber, Julien
name: Hourmant, Baptiste
name: Delbove, Agathe
name: Frérou, Aurélien
name: Morin, Jean
name: Egreteau, Pierre Yves
name: Seguin, Philippe
name: Reignier, Jean
name: Lascarrou, Jean-Baptiste
name: Canet, Emmanuel
Publisher: name: figshare
Year: 2022
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1: Appendix S1. List of the 13 participating intensive care units in France. Appendix S2. Supplementary Methods. Table S1. Multivariable analysis to identify factors associated with day-28 mortality. Table S2. Univariate analysis to identify factors associated with day-28 mortality among the 3 groups of patients (Early steroids, late steroids, and no steroids). e-Table S3. Multivariable analysis to identify factors associated with day-28 mortality among the 3 groups of patients (Early steroids, late steroids, and no steroids). Table S4. Multivariable analysis to identify factors associated with intubation. Figure S1. Ventilator-associated pneumonia: probability in each treatment group. Figure S2. Bloodstream infection: probability in each treatment group.
High accuracy Yb optical lattice clock: frequency comparisons and contributions to International Atomic Time
Creators: name: Goti, Irene
Publisher: name: Zenodo
Year: 2023
Subjects: Frequency metrology, optical lattice clock, SI second

description: Ph.D. defence presentation, Politecnico di Torino.
description: This work is supported by: the European Metrology Program for Innovation and Research (EMPIR) Projects 18SIB05 ROCIT and 20FUN08 Nextlasers, which have received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
Organochlorine insecticides DDT and chlordane in relation to survival following breast cancer: Organochlorine Insecticides and Breast Cancer
Creators: name: Engel, Lawrence S.
name: Wolff, Mary S.
name: Gammon, Marilie D.
name: Parada, Humberto
name: Teitelbaum, Susan L.
name: Eng, Sybil M.
name: Neugut, Alfred I.
name: Cleveland, Rebecca J.
name: Khankari, Nikhil K.
name: White, Alexandra J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Organochlorine insecticides have been studied extensively in relation to breast cancer incidence and results from two meta-analyses have been null for late-life residues, possibly due to measurement error. Whether these compounds influence survival remains to be fully explored. We examined associations between organochlorine insecticides (p,p’-DDT, its primary metabolite, p,p’-DDE, and chlordane) assessed shortly after diagnosis and survival among women with breast cancer. A population-based sample of women diagnosed with a first primary invasive or in situ breast cancer in 1996–1997 and with available organochlorine blood measures (n=633) were followed for vital status through 2011. After follow-up of 5 and 15 years, we identified 55 and 189 deaths, of which 36 and 74, respectively, were breast cancer-related. Using Cox regression models, we estimated the multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for lipid-adjusted organochlorine concentrations with all-cause and breast cancer-specific mortality. At 5 years after diagnosis, the highest tertile of DDT concentration was associated with all-cause (HR=2.19; 95%CI: 1.02, 4.67) and breast cancer-specific (HR=2.72; 95%CI: 1.04, 7.13) mortality. At 15 years, middle tertile concentrations of DDT (HR=1.42; CI 0.99, 2.06) and chlordane (HR=1.42; 95%CI: 0.94, 2.12) were modestly associated with all-cause and breast cancer-specific mortality. Third tertile DDE concentrations were inversely associated with 15-year all-cause mortality (HR=0.66; 95%CI: 0.44, 0.99). This is the first population-based study in the United States to show that DDT may adversely impact survival following breast cancer diagnosis. Further studies are warranted given the high breast cancer burden and the ubiquity of these chemicals.