cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On correlation between the hardness-to-strength ratio and the plastic Poisson's ratio of nanoporous gold
Creators: name: Liu, Ling-Zhi
name: Zhang, Ye-Yuan
name: Jin, Hai-Jun
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: We report that hardness-to-strength ratio is not correlated with plastic Poisson's ratio in nanoporous gold, arguing against the Shaw–Sata relation. Instead, the hardness-to-strength ratio of nanoporous gold increases consistently with increasing rate of strain hardening. Furthermore, in samples with near-zero hardening in compression, the hardness-to-strength ratio does not deviate much from 1.0 when the plastic Poisson's ratio increases up to 0.27, echoing Miller's simulation. Current study suggests that the hardness-to-strength ratio is not a restraint factor, but an indicator of the strain hardening rate for nanoporous gold, which might apply to other porous materials with low-to-medium relative densities. A widely used correlation between the hardness-to-strength ratio and the plastic Poisson's ratio is invalid in nanoporous gold; instead, its hardness is sensitive to the strain hardening in compression.
Sonnenfleckenzeichnung Nr. 25.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.01.1983, 09:00, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 131.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.06.1983, 08:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
The Hyades open cluster is chemically inhomogeneous
Creators: name: Liu, F.
name: Yong, D.
name: Asplund, M.
name: Ramirez, I.
name: Melendez, J.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a high-precision differential abundance analysis of 16 solar-type stars in the Hyades open cluster based on high resolution, high signal-to-noise ratio (S/N ~ 350 - 400) spectra obtained from the McDonald 2.7m telescope. We derived stellar parameters and differential chemical abundances for 19 elements (C, O, Na, Mg, Al, Si, S, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, and Ba) with uncertainties as low as ~ 0.01 - 0.02 dex. Our main results include: (1) there is no clear chemical signature of planet formation detected among the sample stars, i.e., no correlations in abundances versus condensation temperature; (2) the observed abundance dispersions are a factor of ~ 1.5 - 2 larger than the average measurement errors for most elements; (3) there are positive correlations, of high statistical significance, between the abundances of at least 90% of pairs of elements. We demonstrate that none of these findings can be explained by errors due to the stellar parameters. Our results reveal that the Hyades is chemically inhomogeneous at the 0.02 dex level. Possible explanations for the abundance variations include (1) inhomogeneous chemical evolution in the proto-cluster environment, (2) supernova ejection in the proto-cluster cloud, and (3) pollution of metal-poor gas before complete mixing of the proto-cluster cloud. Our results provide significant new constraints on the chemical composition of open clusters and a challenge to the current view of Galactic archeology.
description: 17 pages, 17 figures, accepted for publication in MNRAS
Deciphering the competitive inhibition of dihydropteroate synthase by 8 marcaptoguanine analogs: enhanced potency in phenylsulfonyl fragments
Creators: name: Das, Bratin Kumar
name: Chakraborty, Debashree
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: The emergence of sulfa-drug resistance and reduced efficacy of pterin-based analogs towards Dihydropteroate synthase (DHPS) inhibition dictate a pressing need of developing novel antimicrobial agents for immune-compromised patients. Recently, a series of 8-Marcaptoguanin (8-MG) derivatives synthesized for 6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (experimental KD ∼ 100–.0.36) showed remarkable homology with the pteroic-acid and serve as a template for product antagonism in DHPS. The present work integrates ligand-based drug discovery techniques with structure-based docking, enhanced MD simulation, and MM/PBSA techniques to demonstrate the essential features of 8-MG analogs which make it a potent inhibitor for DHPS. The delicate balance in hydrophilic, hydrophobic substitutions on the 8-MG core is the crucial signature for DHPS inhibition. It is found that the dynamic interactions of active compounds are mainly dominated by consistent hydrogen bonding network with Asp 96, Asn 115, Asp 185, Ser 222, Arg 255 and π-π stacking, π-cation interactions with Phe 190, Lys 221. Further, two new 8-MG compounds containing N-phenylacetamide (compound S1, ΔGbind-eff = –62.03 kJ/mol) and phenylsulfonyl (compound S3, ΔGbind-eff = −71.29 kJ/mol) fragments were found to be the most potent inhibitor of DHPS, which stabilize the flexible pABA binding loop, thereby increasing their binding affinity. MM/PBSA calculation shows electrostatic energy contribution to be the principal component in stabilizing the inhibitors in the binding pocket. This fact is further confirmed by the higher energy barrier obtained in umbrella sampling for this class of inhibitors. Communicated by Ramaswamy H. Sarma
An Application Of Sar???yadhamma In the working of Business Network Management Staff, Kasikornthai Bank
Creators: name: Punnapha Boonrungkiat
Publisher: name: Buddhist Studies Foundation Wat Buranasiri Matayaram
Year: 2023
Subjects: Saranee Dharma 6
Kasikorn Bank Officers

description: Journal of Dhamma for Life, 29, 3, pp.1-10
Newton-Okounkov bodies and complexity functions
Creators: name: Fulger, Mihai
name: Schmitz, David
Publisher: name: arXiv
Year: 2016
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics

description: We show that quite universally the holonomicity of the complexity function of a big divisor on a projective variety does not predict the polyhedrality of the Newton-Okounkov body associated to every flag.
Hybrid Perturbation methods based on Statistical Time Series models
Creators: name: San-Juan, Juan Félix
name: San-Martín, Montserrat
name: Pérez, Iván
name: López, Rosario
Publisher: name: arXiv
Year: 2016
Subjects: subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: In this work we present a new methodology for orbit propagation, the hybrid perturbation theory, based on the combination of an integration method and a prediction technique. The former, which can be a numerical, analytical or semianalytical theory, generates an initial approximation that contains some inaccuracies derived from the fact that, in order to simplify the expressions and subsequent computations, not all the involved forces are taken into account and only low-order terms are considered, not to mention the fact that mathematical models of perturbations not always reproduce physical phenomena with absolute precision. The prediction technique, which can be based on either statistical time series models or computational intelligence methods, is aimed at modelling and reproducing missing dynamics in the previously integrated approximation. This combination results in the precision improvement of conventional numerical, analytical and semianalytical theories for determining the position and velocity of any artificial satellite or space debris object. In order to validate this methodology, we present a family of three hybrid orbit propagators formed by the combination of three different orders of approximation of an analytical theory and a statistical time series model, and analyse their capability to process the effect produced by the flattening of the Earth. The three considered analytical components are the integration of the Kepler problem, a first-order and a second-order analytical theories, whereas the prediction technique is the same in the three cases, namely an additive Holt-Winters method.
description: 27 pages, 8 figures
Sonnenfleckenzeichnung Nr. 118.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.06.1983, 08:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Leishmanicidal and cytotoxic activity of essential oil from the fruit peel of Myrciaria floribunda (H. West ex Willd.) O. Berg: Molecular docking and molecular dynamics simulations of its major constituent onto Leishmania enzyme targets
Creators: name: da Silva Barbosa, Deyzi Caroline
name: Holanda, Vanderlan Nogueira
name: Ghosh, Arabinda
name: Maia, Rafael Trindade
name: da Silva, Welson Vicente
name: de Menezes Lima, Vera Lúcia
name: da Silva, Márcia Vanusa
name: dos Santos Correia, Maria Tereza
name: de Figueiredo, Regina Celia Bressan Queiroz
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Cutaneous Leishmaniasis (CL) is a neglected disease characterized by highest morbidity rates worldwide. The available treatment for CL has several limitations including serious side effects and resistance to the treatment. Herein we aimed to evaluate the activity of essential oil from the peel of Myrciaria floribunda fruits (MfEO) on Leishmania amazonensis. The cytotoxic potential of MfEO on host mammalian cells was evaluated by MTT. The in vitro leishmanicidal effects of MfEO were investigated on the promastigote and intracellular amastigote forms. The ultrastructural changes induced by MfEO were evaluated by Scanning Electron Microscopy (SEM). The molecular docking of the major compounds δ-Cadinene, γ-Cadinene, γ-Muurolene, α-Selinene, α-Muurolene and (E)–Caryophyllene onto the enzymes trypanothione reductase (TreR) and sterol 14-alpha demethylase (C14DM) were performed. Our results showed that MfEO presented moderate cytotoxicity for Vero cells and macrophages. The MfEO inhibited the growth of promastigote and the survival of intracellular amastigotes, in a dose- and time- dependent way. The MfEO presented high selectivity towards amastigote forms, being 44.1 times more toxic for this form than to macrophages. Molecular docking analysis showed that the major compounds of MfEO interact with Leishmania enzymes and that δ-Cadinene (δ-CAD) presented favorable affinity energy values over TreR and C14DM enzymes, when compared with the other major constituents. Molecular dynamics (MD) simulation studies revealed a stable binding of δ-CAD with lowest binding free energy values in MMGBSA assay. Our results suggested that δ-CAD may be a potent inhibitor of TreR and C14DM enzymes. Communicated by Ramaswamy H. Sarma
Synthesis, anti-diabetic and in silico QSAR analysis of flavone hydrazide Schiff base derivatives
Creators: name: Jamil, Waqas
name: Shaikh, Javeria
name: Yousuf, Maria
name: Taha, Muhammad
name: Khan, Khalid Mohammed
name: Shah, Syed Adnan Ali
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 60506 Virology

description: This study reports synthesis of flavone hydrazide Schiff base derivatives with diverse functionalities for the cure of diabetic mellitus and their a-glucosidase inhibitor and in silico studies. In this regard, Flavone derivatives 1–20 has synthesized and characterized by various spectroscopic techniques. These compounds showed significant potential towards a-glucosidase enzyme inhibition activity and found to be many fold better active than the standard Acarbose (IC50 = 39.45 ± 0.11 µM). The IC50values ranges 1.02–38.1 µM. Among these, compounds 1(IC50 = 4.6 ± 0.23 µM), 2(IC50 = 1.02 ± 0.2 µM), 3(IC50 = 7.1 ± 0.11 µM), 4(IC50 = 8.3 ± 0.34 µM), 5(IC50 = 7.4 ± 0.15 µM), 6(IC50 = 8.5 ± 0.27 µM) and 18 (IC50 = 1.09 ± 0.26 µM) showed highest activity. It was revealed that the analogues having –OH substitution have higher activity than their look likes. The molecular docking analysis revealed that these molecules have high potential to interact with the protein molecule and have high ability to bind with the enzyme. Furthermore, in silico pharmacokinetics, physicochemical studies were also performed for these derivatives. The bioavailability radar analysis explored that of all these compounds have excellent bioavailability for five (5) descriptors, however, the sixth descriptor of instauration is slightly increased in all compounds. Communicated by Ramaswamy H. Sarma
An improvement of isochronous mass spectrometry: Velocity measurements using two time-of-flight detectors
Creators: name: Shuai, P.
name: Xu, X.
name: Zhang, Y. H.
name: Xu, H. S.
name: Litvinov, Yu. A.
name: Wang, M.
name: Tu, X. L.
name: Blaum, K.
name: Zhou, X. H.
name: Yuan, Y. J.
name: Yan, X. L.
name: Chen, X. C.
name: Chen, R. J.
name: Fu, C. Y.
name: Ge, Z.
name: Huang, W. J.
name: Xing, Y. M.
name: Zeng, Q.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Isochronous mass spectrometry (IMS) in storage rings is a powerful tool for mass measurements of exotic nuclei with very short half-lives down to several tens of microseconds, using a multicomponent secondary beam separated in-flight without cooling. However, the inevitable momentum spread of secondary ions limits the precision of nuclear masses determined by using IMS. Therefore, the momentum measurement in addition to the revolution period of stored ions is crucial to reduce the influence of the momentum spread on the standard deviation of the revolution period, which would lead to a much improved mass resolving power of IMS. One of the proposals to upgrade IMS is that the velocity of secondary ions could be directly measured by using two time-of-flight (double TOF) detectors installed in a straight section of a storage ring. In this paper, we outline the principle of IMS with double TOF detectors and the method to correct the momentum spread of stored ions.
description: Accepted by Nuclear Inst. and Methods in Physics Research, B
title: Dysphagie in der Pädiatrie
Creators: name: Kraus, Fabian
name: Hagen, Rudolf
name: Shehata-Dieler, Wafaa
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund In der Dysphagiologie bei Erwachsenen hat sich in den letzten Jahren ein standardisiertes Verfahren für Schluckuntersuchungen bewährt. Dieses Verfahren hat sich interdisziplinär durchgesetzt und wird in der Literatur unter den einzelnen Fachdisziplinen kontrovers diskutiert.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP)
Sonnenfleckenzeichnung Nr. 148.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.07.1983, 07:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Die Beziehung der vormaligen Benediktinerabtei St. Peter auf dem Schwarzwald zu ihren Besitzungen auf dem Territorium der heutigen Schweiz von der Gründung bis ins 16. Jahrhundert
Creators: name: Mühleisen, Hans-Otto
Publisher: name: Edith Stein Jahrbuch
Year: 2025

description: 1645106810
description: Edith Stein Jahrbuch, V. 9 (2003): Edith Stein Jahrbuch, Band 9
title: Reliabilität der deutschen Version des Fragebogens EAT-10 für Kopf-Hals-Tumor-Patienten
Creators: name: Goeze, Almut
name: Zaretsky, Eugen
name: Pluschinski, Petra
name: Grethel, Isabel
name: Steinbach-Hundt, Silke
name: Hey, Christiane
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund EAT-10 (Eating Assessment Tool) ist ein symptom-spezifischer Fragebogen zur systematischen Erfassung von Schluckstörungen. Die ursprüngliche englische Version wurde 2008 von Belafsky et al. [ref:1] entwickelt und validiert an 482 Patienten mit Schluckstörungen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP)
Internal wave attractors examined using laboratory experiments and 3D numerical simulations
Creators: name: Brouzet, Christophe
name: Sibgatullin, Ilias
name: Scolan, H
name: Ermanyuk, E. V.
name: Dauxois, Thierry
Publisher: name: arXiv
Year: 2016
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In the present paper, we combine numerical and experimental approaches to study the dynamics of stable and unstable internal wave attractors. The problem is considered in a classic trapezoidal setup filled with a uniformly stratified fluid. Energy is injected into the system at global scale by the small-amplitude motion of a vertical wall. Wave motion in the test tank is measured with the help of conventional synthetic schlieren and PIV techniques. The numerical setup closely reproduces the experimental one in terms of geometry and the operational range of the Reynolds and Schmidt numbers. The spectral element method is used as a numerical tool to simulate the nonlinear dynamics of a viscous salt-stratified fluid. We show that the results of three-dimensional calculations are in excellent qualitative and quantitative agreement with the experimental data, including the spatial and temporal parameters of the secondary waves produced by triadic resonance instability. Further, we explore experimentally and numerically the effect of lateral walls on secondary currents and spanwise distribution of velocity amplitudes in the wave beams. Finally, we test the assumption of a bidimensional flow and estimate the error made in synthetic schlieren measurements due to this assumption.
Sufficiency as a confluence for post-growth streams - Report on the integrated analysis of the different schools of thought
Creators: name: Laurent, Éloi
Publisher: name: Zenodo
Year: 2024

description: Within WP 1, Task 3 (March 2023-February 2024) has two objectives:

      To map post-growth studies based on their key insights and contributions to the post-growth agenda;

       To design analytical and institutional paths of convergence between them in order to nourish ToBe shared visions for a new sustainability paradigm.

This report identifies three main contemporary “post-growth streams”: degrowth, Doughnut economy and the Well-being economy;

·          It argues that sufficiency is their point of convergence (or “confluence”);

·          It retraces the history of the notion of sufficiency from the Greek philosophy up until the IPCC definition in 2023;

·          It offers a refined definition of sufficiency and outlines features of “sufficiency policies”;

·          It proposes a visual design for sufficiency, the “social equator”.
Sonnenfleckenzeichnung Nr. 66.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.03.1983, 08:15, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Good Governance Application Affecting Organizational Commitment of Private University Personnel in Bangkok
Creators: name: Teeradej Snongtaweeporn
Publisher: name: Buddhist Studies Foundation Wat Buranasiri Matayaram
Year: 2023
Subjects: Good Governance
Rule of Law Virtue
Participation
Organizational Commitment

description: Journal of Dhamma for Life, 29, 3, 66-80
Sonnenfleckenzeichnung Nr. 42.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.02.1983, 14:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Verdacht auf seronegative RA – eine diagnostische Herausforderung
Creators: name: Diller, Magnus
name: Ehrenstein, Boris
name: Hartung, Wolfgang
name: Fleck, Martin
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: Rheumatoide Arthritis
subject: Seronegativ
subject: M. Whipple
subject: 610 Medical sciences; Medicine

description: Vorgeschichte: Ein 53-jähriger Patient mit einer 2005 erstdiagnostizierten RF und ACPA negativen Rheumatoiden Arthritis wurde vom Hausarzt zur Therapieoptimierung in unsere Klinik eingewiesen. Trotz verschiedenster Therapieversuche mit DMARDs, Biologika (TNF-α-Inhibitoren, IL-1- und IL-6-Blockade,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)
Molecular modeling and dynamics studies of the synthetic small molecule agonists with GPR17 and P2Y1 receptor
Creators: name: Murugesan, Akshaya
name: Nguyen, Phung
name: Ramesh, Thiyagarajan
name: Yli-Harja, Olli
name: Kandhavelu, Meenakshisundaram
name: Saravanan, Konda Mani
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The human Guanine Protein coupled membrane Receptor 17 (hGPR17), an orphan receptor that activates uracil nucleotides and cysteinyl leukotrienes is considered as a crucial target for the neurodegenerative diseases. Yet, the detailed molecular interaction of potential synthetic ligands of GPR17 needs to be characterized. Here, we have studied a comparative analysis on the interaction specificity of GPR17-ligands with hGPR17 and human purinergic G protein-coupled receptor (hP2Y1) receptors. Previously, we have simulated the interaction stability of synthetic ligands such as T0510.3657, AC1MLNKK, and MDL29951 with hGPR17 and hP2Y1 receptor in the lipid environment. In the present work, we have comparatively studied the protein-ligand interaction of hGPR17-T0510.3657 and P2Y1-MRS2500. Sequence analysis and structural superimposition of hGPR17 and hP2Y1 receptor revealed the similarities in the structural arrangement with the local backbone root mean square deviation (RMSD) value of 1.16 Å and global backbone RMSD value of 5.30 Å. The comparative receptor-ligand interaction analysis between hGPR17 and hP2Y1 receptor exposed the distinct binding sites in terms of geometrical properties. Further, the molecular docking of T0510.3657 with the hP2Y1 receptor have shown non-specific interaction. The experimental validation also revealed that Gi‐coupled activation of GPR17 by specific ligands leads to the adenylyl cyclase inhibition, while there is no inhibition upon hP2Y1 activation. Overall, the above findings suggest that T0510.3657-GPR17 binding specificity could be further explored for the treatment of numerous neuronal diseases. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 156.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.07.1983, 06:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: SMILE – Wo geht die Reise hin?
Creators: name: Blum, Marcus
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: 2006 stellten Sekundo und Blum die ersten klinischen Ergebnisse der Refraktiven Lentikel-Extraktion (FLEx) vor. Diese wurde 2 Jahre später durch die minimalinvasive Technik SMILE ergänzt. Dieses Verfahren der minimalinvasiven Lentikelextraktion hat sich mittlerweile mit über 400.000 Eingriffen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 24. Jahrestagung der Regionalgesellschaft der Augenärzte Sachsen-Anhalts und Thüringens
Sonnenfleckenzeichnung Nr. 37.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 08.02.1983, 10:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Typed realizability for first-order classical analysis
Creators: name: Blot, Valentin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: We describe a realizability framework for classical first-order logic in which realizers live in (a model of) typed λμ-calculus. This allows a direct interpretation of classical proofs, avoiding the usual negative translation to intuitionistic logic. We prove that the usual terms of Gödel's system T realize the axioms of Peano arithmetic, and that under some assumptions on the computational model, the bar recursion operator realizes the axiom of dependent choice. We also perform a proper analysis of relativization, which allows for less technical proofs of adequacy. Extraction of algorithms from proofs of Π02 formulas relies on a novel implementation of Friedman's trick exploiting the control possibilities of the language. This allows to have extracted programs with simpler types than in the case of negative translation followed by intuitionistic realizability.
title: Herausfordernde Hornhautchirurgie – innovative lamelläre Keratoplastik
Creators: name: Chankiewitz, Erik
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: In der Universitätsaugenklinik in Halle werden neben Patienten mit lamellären oder perforierender (Erst-)keratoplastik vermehrt Patienten mit komplexen Ausgangssituationen versorgt. Einerseits führen chronische Erkrankungen, wie Herpeskeratitis und Transplantatabstoßungsreaktionen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 24. Jahrestagung der Regionalgesellschaft der Augenärzte Sachsen-Anhalts und Thüringens
Integrating the Value of Faith According to Theravada Buddhist Philosophy Towards the Lives of Thai People
Creators: name: Phra Prasan Jayabhirato Aramvanich,
Publisher: name: Buddhist Studies Foundation Wat Buranasiri Matayaram
Year: 2023
Subjects: Integration
Value
Faith
Theravada Buddhist Philosophy
Lives of Thai People

description: Journal of Dhamma for Life, 29, 3, 92-108
Leishmanicidal and cytotoxic activity of essential oil from the fruit peel of Myrciaria floribunda (H. West ex Willd.) O. Berg: Molecular docking and molecular dynamics simulations of its major constituent onto Leishmania enzyme targets
Creators: name: da Silva Barbosa, Deyzi Caroline
name: Holanda, Vanderlan Nogueira
name: Ghosh, Arabinda
name: Maia, Rafael Trindade
name: da Silva, Welson Vicente
name: de Menezes Lima, Vera Lúcia
name: da Silva, Márcia Vanusa
name: Correia, Maria Tereza dos Santos
name: de Figueiredo, Regina Celia Bressan Queiroz
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Cutaneous Leishmaniasis (CL) is a neglected disease characterized by highest morbidity rates worldwide. The available treatment for CL has several limitations including serious side effects and resistance to the treatment. Herein we aimed to evaluate the activity of essential oil from the peel of Myrciaria floribunda fruits (MfEO) on Leishmania amazonensis. The cytotoxic potential of MfEO on host mammalian cells was evaluated by MTT. The in vitro leishmanicidal effects of MfEO were investigated on the promastigote and intracellular amastigote forms. The ultrastructural changes induced by MfEO were evaluated by Scanning Electron Microscopy (SEM). The molecular docking of the major compounds δ-Cadinene, γ-Cadinene, γ-Muurolene, α-Selinene, α-Muurolene and (E)–Caryophyllene onto the enzymes trypanothione reductase (TreR) and sterol 14-alpha demethylase (C14DM) were performed. Our results showed that MfEO presented moderate cytotoxicity for Vero cells and macrophages. The MfEO inhibited the growth of promastigote and the survival of intracellular amastigotes, in a dose- and time- dependent way. The MfEO presented high selectivity towards amastigote forms, being 44.1 times more toxic for this form than to macrophages. Molecular docking analysis showed that the major compounds of MfEO interact with Leishmania enzymes and that δ-Cadinene (δ-CAD) presented favorable affinity energy values over TreR and C14DM enzymes, when compared with the other major constituents. Molecular dynamics (MD) simulation studies revealed a stable binding of δ-CAD with lowest binding free energy values in MMGBSA assay. Our results suggested that δ-CAD may be a potent inhibitor of TreR and C14DM enzymes. Communicated by Ramaswamy H. Sarma
FEASE: Fast and Expressive Asymmetric Searchable Encryption
Creators: name: ENTRUST Horizon Europe
Publisher: name: Zenodo
Year: 2024

description: Published elsewhere. USENIX Security Symposium 2024

 

ABSTRACT

Asymmetric Searchable Encryption (ASE) is a promising cryptographic mechanism that enables a semi-trusted cloud server to perform keyword searches over encrypted data for users. To be useful, an ASE scheme must support expressive search queries, which are expressed as conjunction, disjunction, or any Boolean formulas. In this paper, we propose a fast and expressive ASE scheme that is adaptively secure, called FEASE. It requires only 3 pairing operations for searching any conjunctive set of keywords independent of the set size and has linear complexity for encryption and trapdoor algorithms in the number of keywords. FEASE is based on a new fast Anonymous Key-Policy Attribute-Based Encryption (A-KP-ABE) scheme as our first proposal, which is of independent interest. To address optional protection against keyword guessing attacks, we extend FEASE into the first expressive Public-Key Authenticated Encryption with Keyword Search (PAEKS) scheme. We provide implementations and evaluate the performance of all three schemes, while also comparing them with the state of the art. We observe that FEASE outperforms all existing expressive ASE constructions and that our A-KP-ABE scheme offers anonymity with efficiency comparable to the currently fastest yet non-anonymous KP-ABE schemes FAME (ACM CCS 2017) and FABEO (ACM CCS 2022).

 

AUTHORS

Long Meng, University of SurreyLiqun Chen, University of SurreyYangguang Tian, University of SurreyMark Manulis, Universität der Bundeswehr MünchenSuhui Liu, Southeast University
Sonnenfleckenzeichnung Nr. 11.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.01.1983, 09:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 73.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.03.1983, 07:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Social Innovation for Farmer Development of the Office of Farmers' Reconstruction and Development Fund
Creators: name: Phatchanokrat Yoorot,
Publisher: name: Buddhist Studies Foundation Wat Buranasiri Matayaram
Year: 2023
Subjects: Farmers' Reconstruction and Development Fund
Social Innovation
Farmers' Debt

description: Journal of Dhamma for Life, 29, 3, 120-133
A Broadband Micro-machined Far-Infrared Absorber
Creators: name: Wollack, Edward J.
name: Datesman, Aaron M.
name: Jhabvala, Christine A.
name: Miller, Kevin H.
name: Quijada, Manuel A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: The experimental investigation of a broadband far-infrared meta-material absorber is described. The observed absorptance is $>\,0.95$ from ${\rm 1-20\,THz}$ (${\rm 300-15\,μm}$) over a temperature range spanning ${\rm 5-300\,K}$. The meta-material, realized from an array of tapers ${\rm \approx 100\,μm}$ in length, is largely insensitive to the detailed geometry of these elements and is cryogenically compatible with silicon-based micro-machined technologies. The electromagnetic response is in general agreement with a physically motivated transmission line model.
description: 6 pages, 2 figures, published -- Review of Scientific Instruments 87, 054701 (2016)
Synthesis, characterization, anticancer and in silico studies of a pyrazole-tethered thiazolidine-2,4-dione derivative
Creators: name: Alshammari, Musherah M.
name: Soury, Raoudha
name: Alenezi, Khalaf M.
name: Mushtque, Md.
name: Rizvi, M. Moshahid Alam
name: Haque, Ashanul
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A new pyrazole-tethered thiazolidine-2,4-dione derivative (8) has been synthesized by the Knoevenagel condensation of 3-(4-nitrophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (4) and 3-(2,4-dioxothiazolidin-3-yl)propanenitrile (7). The structure of the final compound was confirmed by standard spectroscopic techniques including IR spectroscopy, 1H-NMR spectroscopy, and ESI-MS mass spectrometry. Molecular features including frontier molecular orbital (HOMO-LUMO) energies, reactivity descriptors and molecular electrostatic potential (ESP) of the title molecule were determined using density functional theory (DFT) calculation. The in vitro cytotoxicity of both the intermediate (4) and final (8) compounds were investigated against cancerous (SW-480 and MCF-7) and normal (HEK-293) cell lines by MTT assay. Compound (8) displayed higher activity than (4) with higher sensitivity against breast cancer cell line and lesser toxicity. The experimental data were further complemented by docking and absorption, distribution, metabolism, and excretion (ADME) studies. Communicated by Ramaswamy H. Sarma
The Antecedents of Express Delivery Service Company Selection and Customer Satisfaction: Behavioral Intention from Bangkok, Thailand
Creators: name: Tippawan Lertatthakornkit
Publisher: name: Buddhist Studies Foundation Wat Buranasiri Matayaram
Year: 2023
Subjects: Customer Satisfaction
Behavioral Intention
Express Delivery Service Company
Bangkok

description: Journal of Dhamma for Life, 29, 3, 145-157
Propagation of radiation pulses through gas-plasma mixtures
Creators: name: Marzlin, Karl-Peter
name: Panwar, Anuraj
name: Razul, M. Shajahan G.
name: Sanders, Barry C.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We determine the linear optical susceptibility of a radiation pulse propagating through a mixture of a gas of atoms or molecules and a plasma. For a specific range of radiation and plasma frequencies, resonant generation of volume plasmons significantly amplifies the radiation intensity. The conditions for resonant amplification are derived from the dispersion relations in the mixture, and the amplification is demonstrated in a numerical simulation of pulse propagation.
description: 17 pages, 9 figures
Sonnenfleckenzeichnung Nr. 163.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.07.1983, 06:30, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 147.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.07.1983, 06:45, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Verbesserung der endoskopischen Dysphagiediagnostik bei Patienten mit Kopf-Halstumoren mittels NBI
Creators: name: Pflug, C.
name: Koseki, J.
name: Flügel, T.
name: Niessen, A.
name: Müller, F.
name: Nienstedt, J.
Publisher: name: German Medical Science GMS Publishing House
Year: 2016
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung Schluckstörungen sind eine häufige Folge der Therapie von Kopf-Halstumoren [ref:3], [ref:4]. Die Evaluation des Schluckvorganges erfolgt heute routinemäßig mittels der fiberoptisch endoskopischen Evaluation des Schluckvorganges (FEES) [ref:2].[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 33. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP)
Sonnenfleckenzeichnung Nr. 83.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.04.1983, 07:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1983

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)