cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Safety Effectiveness and Crash Cost Benefit of Red Light Cameras in Missouri
Creators: name: Claros, Boris
name: Sun, Carlos
name: Edara, Praveen
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Objective Red light cameras (RLC) have generated heated discussions over issues of safety effectiveness, revenue generation, and procedural due process. This study focuses on the safety evaluation of RLC in Missouri, including the economic valuation of safety benefits. The publication of the national Highway Safety Manual (HSM) in 2010 produced statistical safety models for intersections and spurred the calibration of these models to local conditions. Methods This study adds to existing knowledge by applying the latest statistical methodology presented in the HSM and more current data. Driver behavior constantly changes due in part to driving conditions and the use of technology. The safety and economic benefit evaluation was performed using the Empirical Bayes method which accounts for regression to the mean bias. For the economic benefit evaluation, the KABCO crash severity scale and crash cost estimates were used. A total of 24 four-leg urban intersections were randomly selected from a master list of RLC in Missouri from 2006 to 2011. Additionally, 35 comparable non-treated intersections were selected for the analysis. Results and Conclusions The implementation of RLC reduced overall angle crashes by 11.6% while rear end crashes increased by 16.5%. The net economic crash cost-benefit of the implementation of RLC was $35,269 per site per year in 2001 dollars (approximately $47,000 in 2015 dollars). Thus RLC produced a sizable net positive safety benefit that is consistent with previous statistical studies.
Synthesis and antimicrobial evaluation of some new N-pyridinium, quinolinium, and isoquinolinium sulfonate derivatives
Creators: name: Fadda, Ahmed Ali
name: El-Mekawy, Rasha El-Demerdashi
name: AbdelAal, Mohammed Taha
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: 1,3-propane- and/or 1,4-butane sultone (sultones are internal esters of hydroxyl sulfonic acid) are used as a chemical intermediate to introduce sulfopropyl and/or sulfobutyl groups into heterocyclic molecules and to confer water solubility and anionic character to the molecules. Therefore, the synthesis of three novel functionalized N-sulfonates is described. These sulfonates contain pyridyl (2a–f), quinolyl (4a–m), and isoquinolyl (6a,b) functional groups with potential biological activity. The synthesized quaternary ammonium salts, 3-(2 or 4-arylpyridinium-1-yl)propane or butane-1-sulfonate (2a–f), 3-(alkylquinolinium-1-yl)propane or butane-1-sulfonate (4a–m), and 3-(alkylisoquinolinium-1-yl)propane or butane-1-sulfonate (6a,b), were screened for their antimicrobial and antifungal activities. Among all tested compounds, it was found that compound 4-(4-carboxypyridinium-1-yl)butane-1-sulfonate (2f) showed high activity against Gram-positive bacteria, Gram-negative bacteria, and tested fungi. Most of the compounds showed a moderate degree of antimicrobial activity. The structures of these compounds were confirmed on the basis of their analytical and spectral data (infrared, 1H-NMR and 13C-NMR spectroscopy, and mass spectral data).
Additional file 14 of Genomic and transcriptomic evidence of light-sensing, porphyrin biosynthesis, Calvin-Benson-Bassham cycle, and urea production in Bathyarchaeota
Creators: name: Pan, Jie
name: Zhou, Zhichao
name: Béjà, Oded
name: Cai, Mingwei
name: Yang, Yuchun
name: Liu, Yang
name: Gu, Ji-Dong
name: Li, Meng
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 14: Supplementary data 1. The explanation for gene abbreviations using in Fig. 2 and 4, Table S4, and S6.
Initial steps for high-throughput phenotyping in vineyards
Creators: name: Herzog, K.
name: Roscher, R.
name: Wieland, M.
name: Kicherer, A.
name: Läbe, T.
name: Förstner, W.
name: Kuhlmann, H.
name: Töpfer, R.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The evaluation of phenotypic characters of grapevines is required directly in vineyards and is strongly limited by time, costs and the subjectivity of person in charge. Sensor-based techniques are prerequisite in order to allow non-invasive phenotyping of individual plant traits, to increase the quantity of object records and to reduce error variation. Thus, a Prototype-Image-Acquisition-System (PIAS) was developed for semi-automated capture of geo-referenced images in an experimental vineyard. Different strategies were tested for image interpretation using MATLAB®. The interpretation of images from the vineyard with real background is more practice-oriented but requires the calculation of depth maps. Different image analysis tools were verified in order to enable contactless and non-invasive detection of bud burst and quantification of shoots at an early developmental stage (BBCH 10) and enable fast and accurate determination of the grapevine berry size at BBCH 89. Depending on the time of image acquisition at BBCH 10 up to 94 % of green shoots were visible in images. The mean berry size (BBCH 89) was recorded non-invasively with a precision of 1 mm.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 1 (2014): Vitis
Collaborative Online International Learning With Prelicensure Nursing Students: Teaching Family-Centered Care Through a Global Perspective.
Creators: name: Szylit, Regina
name: Reis di Gregório, Ana Carolina
name: Cosgrove, Beth
name: Thiago Pereira da Silva, Lucas
name: Rodrigues Dos Santos, Maiara
name: Woodley, Lisa
name: Grant, Gabrielle
Publisher: name: SAGE Publications
Year: 2024

description: A Collaborative Online International Learning (COIL) experience was designed for prelicensure nursing students taking a pediatric course in the United States and in Brazil, to teach family-centered care to develop inclusive, global nursing practices. The purpose of this study is to describe prelicensure nursing student learning of family-centered care concepts facilitated by COIL. For data collection, six focus groups with 37 students were conducted across both universities. Data were analyzed using inductive qualitative analysis by each country separately and as a global team. Major themes included understanding the needs of families of children with chronic conditions as impacted by health systems, assigning meanings to family care of children with chronic conditions, applying concepts of family-centered care and self-reflection. Results suggest COIL is a feasible way for prelicensure nursing students to learn family-centered nursing care by operationalizing concepts, from real experiences and increasing cultural awareness.
Trans effect of triphenylphosphine on Ni–S bonds in solid state and DFT/B3LYP optimized structure: Synthesis, spectral and structural studies on (bis(2-ethylhexyl)dithiocarbamato-S,S′)(thiocyanato-N)(triphenylphosphine)nickel(II)
Creators: name: Panneerselvam Valarmathi
name: Narayanaswamy Srinivasan
name: Subbiah Thirumaran
name: Kolandaivelu Saminathan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology
subject: 60506 Virology

description: The compounds [Ni(behdtc)2] (1) and [Ni(behdtc)(NCS)(PPh3)] (2) (where behdtc = bis(2-ethylhexyl)dithiocarbamate) were synthesized and characterized by elemental analyses, electronic, IR, and NMR (1H and 13C) spectroscopy. UV-vis spectral data are consistent with the formation of square-planar nickel complexes. The N13CS2 carbon signal for [Ni(behdtc)(NCS)(PPh3)] is observed at 204.4 ppm with an upfield shift of about 3.8 ppm compared with that found in [Ni(behdtc)2] (208.2 ppm). The observed shielding in [Ni(behdtc)(NCS)(PPh3)] indicates the effect of PPh3 on the mesomeric drift of electron density toward nickel through the thioureide C-N bond. This observation is supported by the higher νC-N values observed in the IR spectrum of the complex 2. A single crystal X-ray analysis of complex 2 proved four coordinated nickel in a distorted square-planar arrangement with a S2NP donor set. A significant asymmetry in the Ni–S bond in 2 (2.1690(10) and 2.2234(10)Å) supports the less effective trans effect of SCN− over PPh3. Molecular electrostatic potential surface map shows that there are no possible sites for nucleophilic attack and S atom of thiocyanate is preferred possible site for electrophilic attack.
Periphragella undetermined
Creators: name: Tabachnick, Konstantin R.
name: Menshenina, Larisa L.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Hexactinellida
Sceptrulophora
Euretidae
Periphragella
Periphragella undetermined

description: Periphragella sp.
(Figures 7–8)
Material. Many dead specimens of Periphragella sp. and fragments with Ferro-Manganese covering of their frameworks. RV ‘Akademik Mstislav Keldysh’—22, sta. 2316, trawl, N from the Piip Volcano, 55 o 36.08’–35.0’ N 167 o 23.04’ –24.46’ E, depth 4294– 4200 m. Dead skeleton of Periphragella with numerous specimens of Caulophacus (C.) hyperboreus (Rossellidae) on it. RV ‘Akademik M.A. Lavrentyev’—75, ROV ‘Comanche’: sta. 16, off Piip Volcano, 55.5774 o N 167.3258 o E, depth 4277–4278 m; sta. 22, spec. 7, Piip Volcano, 55 o 30’36.1” N 167 o 19’27.1” E, depth 3578 m.
Body. The most complete specimens reach about 150 mm high with central atrial cavity from 30 mm to more excavated specimens with walls 1–2 mm in thickness, the lateral tubular outgrowths are about 8 mm in diameter with walls 1–1.5 mm thick.
Framework. The framework is multilayered, 2–4 layers.
Remarks. Unlike the previously described species— Periphragella spiridonovi sp. nov. —these fossil fragments have multilayered walls, which does not allow to refer them to the same species. Nevertheless, their generic assignment is doubtless.
The dead dictyonal skeletons of Periphragella were found to play an important role as substrata on silt bottom. Being relatively lightweight, having rigid dictyonal skeleton structure, the dead skeletons of Periphragella drift off from the rocky areas (Periphragella itself inhabits hard substrata only) to the surface covered by muddy silt and thus provide hard substrata for other benthic organisms, for instance for other hexactinellids—for example, numerous specimens of Caulophacus (C.) hyperboreus (Tabachnick et al., 2023).
description: Published as part of Tabachnick, Konstantin R. & Menshenina, Larisa L., 2025, Deep-sea reef building hexactinellids (Euretidae) from the Bering Sea abyssal zone, pp. 371-382 in Zootaxa 5621 (3) on page 379, DOI: 10.11646/zootaxa.5621.3.5, http://zenodo.org/record/15262842
Phytoextraction of initial cutting of Salix matsudana for Cd and Cu
Creators: name: Wang, Wen-Wen
name: Cheng, Liu Ke
name: Hao, Jie Wei
name: Guan, Xin
name: Tian, Xing-Jun
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Salix species are widely used as vegetation filters because of their flourishing root system and fast growth rate. However, studies have yet to determine whether the root system functions in vegetable filters with mixed heavy metal (HM) pollution or whether initial cutting participates in the phytoextraction of HMs. This study aims to determine the function of the root system and initial cutting as vegetation filters in the absorption and accumulation of Cd and Cu. Thick (>1 cm in diameter) and fine (<1 cm in diameter) initial cuttings of Salix matsudana were planted in a nutrient solution with single and mixed (Cd + Cu) treatments. The roots of several initial cuttings were removed daily to eradicate rhizofiltration. Results revealed that the existence of the root system altered distribution and interaction of Cd and Cu in plant organs and enhanced tolerance and phytoextraction capacity of plants. The initial cuttings could also absorb and accumulate HMs in the early growth stages of willow without roots. Cu inhibited the plant absorption and accumulation of Cd and promoted Cd transport to shoots. Cd inhibited the Cu absorption of the root system. Our study provided essential data regarding woody species as vegetation filters of HM pollution.
Phytoextraction of initial cutting of Salix matsudana for Cd and Cu
Creators: name: Wang, Wen-Wen
name: Cheng, Liu Ke
name: Hao, Jie Wei
name: Guan, Xin
name: Tian, Xing-Jun
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Salix species are widely used as vegetation filters because of their flourishing root system and fast growth rate. However, studies have yet to determine whether the root system functions in vegetable filters with mixed heavy metal (HM) pollution or whether initial cutting participates in the phytoextraction of HMs. This study aims to determine the function of the root system and initial cutting as vegetation filters in the absorption and accumulation of Cd and Cu. Thick (>1 cm in diameter) and fine (<1 cm in diameter) initial cuttings of Salix matsudana were planted in a nutrient solution with single and mixed (Cd + Cu) treatments. The roots of several initial cuttings were removed daily to eradicate rhizofiltration. Results revealed that the existence of the root system altered distribution and interaction of Cd and Cu in plant organs and enhanced tolerance and phytoextraction capacity of plants. The initial cuttings could also absorb and accumulate HMs in the early growth stages of willow without roots. Cu inhibited the plant absorption and accumulation of Cd and promoted Cd transport to shoots. Cd inhibited the Cu absorption of the root system. Our study provided essential data regarding woody species as vegetation filters of HM pollution.
Особенности реализации внедоговорной ответственности в сфере правового обеспечения нанобиобезопасности (Futures of the Implementation of Von-Contractual Liability in the Field of Legal Support of Nanobiosafety)
Creators: name: Эльдарович, Зульфугарзаде Теймур
Publisher: name: Zenodo
Year: 2020
Subjects: law

description: В работе проанализированы основные особенности деликтной ответственности за причинение вреда, вызванного рисками ненадлежащего обеспечения безопасности при разработке и производстве нанобиотехнологий.
The role of selected tree species in industrial sewage sludge/flotation tailing management
Creators: name: Mirosław Mleczek
name: Paweł Rutkowski
name: Przemysław Niedzielski
name: Goliński, Piotr
name: Gąsecka, Monika
name: Tomisław Kozubik
name: Jędrzej Dąbrowski
name: Budzyńska, Sylwia
name: Jarosław Pakuła
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The aim of the study was to estimate the ability of ten tree and bush species to tolerate and accumulate Cd, Cu, Pb, Zn and As species [As(III), As(V) and total organic arsenic] in industrial sewage sludge extremely contaminated with arsenic (almost 27.5 g kg−1) in a pot experiment. The premise being that it will then be possible to select the most promising tree/bush species, able to grow in the vicinity of dams, where sewage sludge/flotation tailings are used as landfill. Six of the ten tested tree species were able to grow on the sludge. The highest content of total As was observed in B. pendula roots (30.0±1.3 mg kg−1 DW), where the dominant As species was the toxic As(V). The efficiency of Cd, Cu, Pb and Zn accumulation was dependent on the tested tree species. The highest biomass in Q. robur (77.3±2.6 g) and A. platanoides (76.0±4.9 g) was observed. A proper planting of selected tree species that are able to thrive on sewage sludge/flotation tailings could be an interesting and promising way to protect dams. By utilizing differences in their root systems and water needs we will be able to reduce the risk of fatal environmental disasters.
Epigenetics as a link between environmental factors and dementia risk
Creators: name: Koulouri, Adamantia
name: Zannas, Anthony S
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Dementia encompasses a broad spectrum of neuropsychiatric disease states marked by cognitive impairments that interfere with day-to-day functioning. Most dementias are complex phenotypes that result from a genome-environment interplay. Epigenetic regulation has emerged as a candidate mechanism for studying this interplay. In this narrative review, we discuss state-of-the-art evidence on environmental exposures relevant to dementia, including nutrition, physical exercise, psychosocial stress, and environmental toxins, and highlight epigenetic mechanisms that have been reported as a putative link between each exposure and dementia risk. We then discuss the clinical implications and future directions of this line of research. An improved understanding of the epigenetic mechanisms involved in dementia pathogenesis can promote the development of novel biomarkers for predicting outcomes but also targeted therapies to intervene early in the course of the disease.
FS_Structuring of clinical posting in the early years of undergraduate clinical training.docx
Creators: name: Maroju, Nanda Kishore
Publisher: name: figshare
Year: 2016
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: This original article describes our experience in structuring clinical postings for content and format. Student feedback suggests that this is effective in improving students' training in history-taking and physical examination.
Impact of observability period on the classification of COPD diagnosis timing among Medicare beneficiaries with lung cancer
Creators: name: Hinton, Sharon Peacock
name: Soppe, Sarah E.
name: Lund, Jennifer L.
name: Metwally, Eman
name: Thompson, Caroline A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Healthcare data such as electronic health records and health insurance claims is a rich resource to study outcomes of chronic medical conditions such as chronic obstructive pulmonary disease (COPD). However, it can be tricky to determine the optimal period of searching the claims to identify the first diagnosis time of a chronic condition. In this study, we explored three approaches to optimize classification of COPD diagnosis based on a variety of Medicare claims search periods and observability (required continuous periods of enrollment) periods. We used a large dataset of Medicare claims linked to SEER cancer registry including more than 158,000 Medicare beneficiaries to identify diagnosis timing of COPD relative to lung cancer diagnosis. We observed that the most efficient approach to classify COPD diagnosis timing is to use all available historical claims data while requiring a minimum of one year of Medicare continuous enrollment. Our findings will help researchers concerned about accuracy of diagnosis timing of chronic conditions such as COPD and loss in sample size, especially when long periods of continuous insurance enrollment isn’t feasible.
Enhanced the strength and ductility of the partially unzipped carbon nanotubes reinforced CuCr matrix composites via optimization of the interface structure
Creators: name: Zhao, Qi
name: Gan, Xueping
name: Lei, Qian
name: Li, Wanyu
name: Zhou, Kechao
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Cancer

description: The different unzipping levels of carbon nanotubes (CNTs) reinforced CuCr matrix composites were fabricated by flake powder metallurgy. The strengthening effect of the different unzipping levels of CNTs in the metal matrix was investigated through scanning electron microscopy, transmission electron microscopy, and tensile tests. When the CNTs were unzipped to the proper level, the unzipped-CNTs/CuCr composite presented primarily enhanced an ultimate tensile strength of 373.7 MPa and a fracture elongation of 18.6%, respectively. The formation of sufficient interface contact areas and interfacial adhesion between unzipped CNTs and CuCr matrix, which were responsible for trade-off in the strength-ductility of the composites. This work provides an insight to understand the strengthening behaviors of unzipped CNTs in the metal matrix composites.
Prognostic value of right ventricular systolic function in cardiac amyloidosis
Creators: name: Bodez, Diane
name: Ternacle, Julien
name: Guellich, Aziz
name: Galat, Arnault
name: Lim, Pascal
name: Radu, Costin
name: Soulef Guendouz
name: Bergoend, Eric
name: Couetil, Jean-Paul
name: Hittinger, Luc
name: Dubois-Randé, Jean-Luc
name: Plante-Bordeneuve, Violaine
name: Jean-François Deux
name: Mohty, Dania
name: Damy, Thibaud
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Hematology
subject: 60506 Virology

description: Background: Right ventricular (RV) dysfunction is a strong predictor of poor outcomes in heart failure. Its prognostic meaning in cardiac amyloidosis (CA) is under-investigated. Methods: Hundred and twenty nine patients with suspected CA and an interventricular septum thickness (IVST) ≥ 12 mm underwent echocardiography with measurement of left ventricular (LV) and RV longitudinal strain (LS), late gadolinium-enhancement (LGE) cardiac MRI, and standard evaluation. Results: Among 82 confirmed CA, types were immunoglobulin light chain (AL, n = 26), hereditary transthyretin (m-TTR, n = 37) and senile (WT-TTR, n = 19). Compared to those without, CA patients had significantly lower RV fractional shortening (RV-FS), tricuspid annular plane systolic excursion (TAPSE), tissue Doppler systolic velocity, and global RV-LS, without any difference among the CA types. RV-LGE, observed in 62% of CA patients, was associated with lower global and basal RV-FS. Median follow-up was 8(2; 16) months. Using multivariate analysis, NYHA-class and low TAPSE independently predicted major adverse cardiac event (MACE) defined as death, heart transplantation and acute heart failure. Independent determinants of TAPSE Conclusions: RV dysfunction is common in CA. Its routine evaluation by a simple TAPSE may be an aid in assessing the prognosis of CA patients.
Targeting chaperone modifications: Innovative approaches to cancer treatment
Creators: name: Schisler, Jonathan C
name: Stewart, Mariah
Publisher: name: Elsevier
Year: 2024

description: Cancer and other chronic diseases are marked by alterations in the protein quality control system, affecting the post-translational destiny of various proteins that regulate, structure, and catalyze cellular processes. Cellular chaperones, also known as heat shock proteins (HSPs), are pivotal in this system, performing protein triage that often determines the fate of proteins they bind to. Grasping the regulatory mechanisms of HSPs and their associated cofactors is crucial for understanding protein quality control in both healthy and diseased states. Recent research has shed light on the interactions within the protein quality control system and how post-translational modifications (PTMs) govern protein interactions, function, and localization, which can drive or inhibit cell proliferation. This body of work encompasses critical elements of the heat shock response, including Heat Shock Protein 70 (HSP70), Heat Shock Protein 90 (HSP90), Carboxyl-terminus of HSC70 Interacting Protein (CHIP), and Heat Shock Protein Organizing Protein (HOP). This review aims to synthesize these advancements, offering a holistic understanding of the system and its response when commandeered by diseases like cancer. We focus on the mechanistic shift in co-chaperone engagement-transitioning from HOP to CHIP in association with HSP70 and HSP90-which could influence cellular growth and survival pathways. A comprehensive examination of PTM-driven regulation within the protein quality control network is presented, highlighting the roles of activation factors, chaperones, and co-chaperones. Our insights aim to inform new strategies for therapeutically targeting diseases by considering the entire heat shock response system.
DFT study on the mechanism of trimolecular radical reactions: isomerisation in small clusters
Creators: name: Valadbeigi, Younes
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Structural and thermodynamic properties of 48 trimolecular clusters containing one radicl and two protic molecules (H2O, NH3, H2O2, CH3OH, HOCl) were studied at B3LYP/6-311++G(3df,3pd) level of theory. These radical-clusters have non-cyclic structures and are stabilised via two inter-molecular hydrogen bonding interactions. The calculated enthalpies of formation of the radical-clusters were generally in the range of −30 to −50 kJ/mol. The calculated activation energies (Ea) of the intra-cluster hydrogen transfers were smaller than 70 kJ/mol. Also, structures and thermodynamics of 15 cyclic molecular clusters as well as multi-hydrogen transfers in them were investigated. The results showed that the stability of the cyclic clusters and activation energies of the multi-hydrogen transfers depend on the cluster size.
title: Parole émergée: 103 corrKP
Creators: name: Ploog, Katja
name: Equoy-Hutin, Séverine
name: Mariani-Rousset, Sophie
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017
Subjects: subject: Français
subject: fra

description: Interaction de soin/au travail : rendez-vous de suivi social (éducateur/psychologue) en structure de soin ambulant en addictologie
Feasibility Evaluation of a Parenting Group for Latina Survivors of Intimate Partner Violence.
Creators: name: Armora Langoni, Eliana
name: Rizo, Cynthia Fraga
name: Jiwatram-Negron, Tina
name: McNaughton Reyes, H Luz
name: Radtke, Spenser R
name: Benavides, Quetzabel
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Intimate partner violence (IPV) is a pervasive concern among Latina women that requires accessible and culturally appropriate services for survivors, including programs to support parenting in the context of IPV. Evaluations of such programs are sparse, limiting understanding of how agencies can best serve Latina survivors who are parents. We conducted a feasibility study of a parenting group for Latina IPV survivors that included an analysis of administrative data, focus groups with program participants (n = 17), and interviews with facilitators (n = 4). Findings center on demand, acceptability, implementation, and recommendations. Overall, the program was well received, and results include suggestions to enhance the program.
Calix[4]arene-(1,2-phenylene-crown-6,crown-6) as an extraordinarily effective macrocyclic receptor for the univalent silver cation
Creators: name: Makrlík, Emanuel
name: Bureš, Michal
name: Vaňura, Petr
name: Asfari, Zouhair
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: On the basis of extraction experiments and γ-activity measurements, the extraction constant corresponding to the equilibrium Ag+(aq) + 1·Cs+ (nb) 1·Ag+(nb) + Cs+ (aq) occurring in the two-phase water–nitrobenzene system (1 = calix[4]arene-(1,2-phenylene-crown-6,crown-6); aq = aqueous phase, nb = nitrobenzene phase) was evaluated as log Kex(Ag+, 1·Cs+) = −1.3 ± 0.1. Further, the very high stability constant of the 1·Ag+ complex in nitrobenzene saturated with water was calculated for a temperature of 25 °C: log βnb(1·Ag +) = 9.3 ± 0.2. Finally, by using quantum mechanical DFT calculations, the most probable structures A and B of this cationic complex species, which are obviously in a dynamic equilibrium, were derived.
Analyzing Patent-Literature for Mapping and Evaluating Covid-19 Innovation
Creators: name: Falciola, Luca
name: Barbieri, Massimo
Publisher: name: Zenodo
Year: 2022
Subjects: SARS-CoV-2
Databases
Patent classifications
Covid-19
Patent search

description: The Covid-19 pandemic has prompted several patent offices worldwide to provide companies and investigators with a large number of new web-based services to cope with logistical and financial problems related to patent proceedings and to foster research and access to information relevant for developing new, more appropriate products and technologies. As of spring 2021, it is still too early to have a complete view of if and how innovation stemming from this new normal situation has been captured and claimed in patent applications. Given the potential financial and strategic importance for some applicants to get a patent quickly granted, the examination and publication of patent applications claiming products and technologies related to Covid-19 may have been accelerated shortly after their filing, at least in some countries. The paper presents the data that has been extracted from patent databases using a methodology described in a recent publication (Falciola L and Barbieri M, Searching and Analyzing Patent-Relevant Information for Evaluating COVID-19 Innovation; posted on Jan. 26th, 2021; available at SSRN: https://ssrn.com/abstract=3771756) about the earliest patent literature explicitly mentioning the relevance of claimed subject matter for Covid-19 pandemic that has been published by major patent offices worldwide. This analysis has been performed in three main dimensions: the claimed technologies (in medical and other domains), the type of patent proceedings (as a regular patent application or utility models, already granted or not), and countries (having their own medical, IP, and economic policies). The patent publication trends have also been studied by distinguishing between two periods (March 2020 - August 2020 and September 2020 - February 2021) to identify how the temporal evolution of the Covid-19 pandemic may have affected the patenting strategies for protecting innovation in an emergency situation, as some evidence would suggest.
description: Website: https://www.tilburguniversity.edu/about/schools/law/departments/tilt/events/tilting-perspectives/2021
description: {"references": ["Falciola, Luca; Barbieri, Massimo (2022) Searching and Analysing Patent-relevant COVID-19 Information World Pat. Inf. 68, 102094"]}
Additional file 1 of Identification and genetic diversity analysis of Rickettsia in Dermacentor nuttalli within inner Mongolia, China
Creators: name: Gui, Zheng
name: Cai, Hao
name: Qi, Dong-Dong
name: Zhang, Shun
name: Fu, Shao-Yin
name: Yu, Jing-Feng
name: Si, Xiao-Yan
name: Cai, Ting
name: Mao, Rui
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Sample information of D. nuttalli populations. Table S2. Primers of PCR and amplification conditions. Table S3 Haplotype distribution of Rickettsia based on the gltA gene. Table S4. FST values among different groups of Rickettsia based on the gltA gene. Table S5. AMOVA of gltA gene of Rickettsia population. Table S6 Haplotype distribution of Rickettsia based on the ompA gene. Table S7 FST values among different groups of Rickettsia based on the ompA gene. Table S8 AMOVA of the ompA gene of the Rickettsia population.
Determinants of Student Learning Satisfaction and Academic Performance in High School Chemistry: a Prediction Model Building Study for Online Learning
Creators: name: Patacsil, Melba C.
Publisher: name: Zenodo
Year: 2024
Subjects: Student Learning Satisfaction
Academic Performance
Online Learning Determinants
Structural Equation Modeling
SmartPLS

description: Learning satisfaction is a key indicator to enriching student learning whether it is face-to-face or online mode of delivery. Learning has shifted more to remote online learning due to the Covid-19 pandemic. This study aimed to identify the determinants of Student Learning Satisfaction (SLS) in online learning and develop a model that represents the relationship of the determinants to SLS. The study explored both internal and external determinants hypothesized to influence SLS among 169 students in grades 9-12 taking Chemistry at the Philippine Science High School Cordillera Administrative Region Campus (PSHS CARC). The internal factors included gender, academic self-concept (ASC), academic motivation (AM), interest to learn (IL), and mental well-being (MW), while the external factors comprised of teacher-related indicators (Teacher), assessment-related indicators (Assessment), learning guide-related indicators (LG) and Knowledge Hub-related indicators (KHub).

The study utilized Structural Equation Modeling (SEM) with SmartPLS software to develop the SLS model and Academic Performance (AP) model. Both online learning platforms used by PSHS CARC, the LG, and KHub, were found to influence student learning satisfaction.

The other important result is that external determinants (LG, KHub, Teacher, Assessment) dominated the SLS models while internal determinants (ASC, AM, IL, MW) dominated the Academic Performance model for the PSHS CARC Chemistry students. The external determinants influence the student's learning satisfaction whilethe internal determinants influence the academic performance of the Chemistry students. Assessment indirectly affected SLS. Another finding is that gender, LG, and ASC directly influenced AP.

The results validate that online learning tools (LG and KHub) are crucial determinants in ensuring learning satisfaction and academic success in the online learning of PSHS CARC Chemistry students.
Drug metabolism and disposition diversity of Ranunculales phytometabolites: a systems perspective
Creators: name: Hao, Da Cheng
name: Yang, Ling
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Introduction: Although investigations in metabolism and pharmacokinetics of Ranunculales phytometabolites are booming, data obtained from human and animal studies have not been summarized as a whole to outline current trends and to predict future development. Areas covered: Here, we highlight the current knowledge, as well as the challenges around the DMPK (drug metabolism and pharmacokinetics) associated concerns in streamlining drug research and therapeutic use of Ranunculales phytometabolites. Data from various in vivo and in vitro models are classified and discussed. DMPK characteristics of Ranunculales phytometabolites are summarized and presented according to the phylogenetic relationship of families and genera. This review also presents an overview of the complex interaction between drug metabolizing enzymes/transporters and phytochemicals, as well as of the most advanced approaches in the relevant field. Expert opinion: Since species-specific differences in DMPK exist, data obtained from animal studies may not be sufficient to predict drug metabolism reactions in humans. Omics-based methodologies (genomics, epigenomics, transcriptomics, proteomics, microbiomics, and metabolomics) should be used to enhance the reliability of DMPK prediction. The fluorescent probes may bridge the gap between conventional models and in vivo clinical studies in humans and provide a consistent basis for DMPK assay development.
Additional file 1 of Changes in bone mineral density after bariatric surgery in patients of different ages or patients with different postoperative periods: a systematic review and meta-analysis
Creators: name: Ou, Xiaodan
name: Chen, Mingguang
name: Xu, Lizhen
name: Lin, Wei
name: Huang, Huibin
name: Chen, Gang
name: Wen, Junping
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Figure S1. Cochrane risk of bias. Figure S2. The forest plot.
Three new monoterpene glucosides from Sibiraea angustata
Creators: name: Zhengzheng Yao
name: Hongdong Liu
name: Xianghong Xu
name: Xiaotian Chen
name: Dongming Zhang
name: Xuewen Lai
name: Xu, Peng
name: Li, Bin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Three new monoterpene glycosides, named sibiraglycoside I(1), J(2) and K(3), were isolated from an aqueous extract of the aerial portion of Sibiraea angustata. Their structures were elucidated on the basis of extensive spectroscopic data analysis (including 1D and 2D NMR and MS experiments) and compared to literature data. Three new monoterpene glucosides were isolated and identified from the plant of Sibiraea angustata.
Association of liver dysfunction with outcomes after percutaneous coronary intervention – a systematic review and meta-analysis
Creators: name: Caldonazo, Tulio
name: Shana’ah, Ahmad
name: Richter, Markus
name: Tasoudis, Panagiotis
name: Kirov, Hristo
name: Doenst, Torsten
name: Haji, Diyar
name: Mukharyamov, Murat
name: Zipprich, Alexander
name: Franz, Marcus
Publisher: name: Springer Nature
Year: 2024

description: Background Liver dysfunction is a known risk factor in the cardiovascular field. It specifically increases perioperative risk in patients undergoing coronary bypass surgery. Since percutaneous coronary intervention (PCI) is the much less invasive procedure for the treatment of coronary artery disease, we aimed to assess the relationship of liver dysfunction with outcomes in patients undergoing PCI. Methods Three libraries were searched (MEDLINE, Web of Science and The Cochrane Library). We performed a meta-analysis of all studies in patients who underwent PCI that provided information on the presence or absence of liver dysfunction. Primary outcome was short-term mortality. Secondary outcomes were major adverse cardio- and cerebrovascular events (MACCE), bleeding and acute kidney injury. Random-effects model was applied. Results Five studies were selected and the data from 10,710,317 patients were included in the final analysis. In comparison with the absence of liver dysfunction, patients with liver dysfunction were associated with higher short-term mortality (OR 2.97, 95%CI 1.23–7.18, p = 0.02), higher MACCE (OR 1.42, 95%CI 1.08–1.87, p = 0.01), and higher bleeding (OR 2.23, 95%CI 1.65-3.00, p < 0.01). There was no significant difference regarding acute kidney injury (OR 1.20, 95%CI 0.50–2.87, p = 0.69). Conclusions The analysis suggests that liver dysfunction in patients undergoing PCI is independently associated with higher risk of short-term mortality and increased occurrence of MACCE and bleeding. However, there appears to be no association to acute kidney injury.
Effect of Nigella sativa L. seed extract on cisplatin-induced delay in gastric emptying in Sprague-Dawley rats
Creators: name: Ambreena Riyaz
name: Nazir, Shahid
name: Khushtar, Mohammad
name: Mishra, Anuradha
name: Yasmeen Jahan
name: Ahmad, Asad
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: The aim of this study was focused on investigating the possible protective effect of Nigella sativa L. seed extract against cisplatin-induced delay in gastric emptying, in a rat model. Twenty-five male Sprague-Dawley rats were divided into five equal groups as follows: Group I or control group, Group II (cisplatin 10 mg/kg, i.p at day 5), Group III (N. sativa L. 250 mg/kg for 5 days + cisplatin 10 mg/kg, i.p on day 5), Group IV (N. sativa L. 500 mg/kg for 5 days + cisplatin 10 mg/kg, i.p on day 5) and Group V (ondansetron 3 mg/kg/day, per os + cisplatin 10 mg/kg, i.p on day 5). Phenol red meal was adopted to estimate gastric emptying in different groups of the rats. Gastric emptying was significantly increased (p N. sativa L. seed extract-pretreated rats (Group III and Group IV) when compared to cisplatin treatment alone (Group II). However, ondansetron produced significantly (p N. sativa L. seed extract.
title: The Arabidopsis Kinome
title: phylogeny and evolutionary insights into functional diversification
titleType: Subtitle
Creators: name: Zulawski, Monika
name: Schulze, Gunnar
name: Braginets, Rostyslav
name: Hartmann, Stefanie
name: Schulze, Waltraud X
Publisher: name: Universität Potsdam
Year: 2020

description: Background Protein kinases constitute a particularly large protein family in Arabidopsis with important functions in cellular signal transduction networks. At the same time Arabidopsis is a model plant with high frequencies of gene duplications. Here, we have conducted a systematic analysis of the Arabidopsis kinase complement, the kinome, with particular focus on gene duplication events. We matched Arabidopsis proteins to a Hidden-Markov Model of eukaryotic kinases and computed a phylogeny of 942 Arabidopsis protein kinase domains and mapped their origin by gene duplication. Results The phylogeny showed two major clades of receptor kinases and soluble kinases, each of which was divided into functional subclades. Based on this phylogeny, association of yet uncharacterized kinases to families was possible which extended functional annotation of unknowns. Classification of gene duplications within these protein kinases revealed that representatives of cytosolic subfamilies showed a tendency to maintain segmentally duplicated genes, while some subfamilies of the receptor kinases were enriched for tandem duplicates. Although functional diversification is observed throughout most subfamilies, some instances of functional conservation among genes transposed from the same ancestor were observed. In general, a significant enrichment of essential genes was found among genes encoding for protein kinases. Conclusions The inferred phylogeny allowed classification and annotation of yet uncharacterized kinases. The prediction and analysis of syntenic blocks and duplication events within gene families of interest can be used to link functional biology to insights from an evolutionary viewpoint. The approach undertaken here can be applied to any gene family in any organism with an annotated genome.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 861
title: Parole émergée: 106 corrKP
Creators: name: Ploog, Katja
name: Equoy-Hutin, Séverine
name: Mariani-Rousset, Sophie
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017
Subjects: subject: Français
subject: fra

description: Interaction de soin/au travail : rendez-vous de suivi social (éducateur/psychologue) en structure de soin ambulant en addictologie
Transcription factor 4 expression in the developing non-human primate brain: a comparative analysis with the mouse brain
Creators: name: Philpot, Benjamin D.
name: Ozarkar, Siddhi S.
name: Smith, Audrey L.
name: Amaral, David G.
name: Vihma, Hanna
name: Burette, Alain C.
name: Bennett, Jeff
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2024

description: Transcription factor 4 (TCF4) has been implicated in a range of neuropsychiatric disorders, including major depressive disorder, bipolar disorder, and schizophrenia. Mutations or deletions in TCF4 cause Pitt-Hopkins syndrome (PTHS), a rare neurodevelopmental disorder. A detailed understanding of its spatial expression across the developing brain is necessary for comprehending TCF4 biology and, by extension, to develop effective treatments for TCF4-associated disorders. However, most current knowledge is derived from mouse models, which are invaluable for preclinical studies but may not fully capture the complexities of human neuropsychiatric phenotypes. This study compared TCF4 expression in the developing mouse brain to its regional and cellular expression patterns in normal prenatal, neonatal, and young adult rhesus macaque brains, a species more relevant to human neurodevelopment. While the general developmental expression of TCF4 is largely conserved between macaques and mice, we saw several interspecies differences. Most notably, a distinct layered pattern of TCF4 expression was clear in the developing macaque neocortex but largely absent in the mouse brain. High TCF4 expression was seen in the inner dentate gyrus of adult mice but not in macaques. Conversely, TCF4 expression was higher in the adult macaque striatum compared to the mouse striatum. Further research is needed to show the significance of these interspecies differences. Still, they underscore the importance of integrating rodent and primate studies to comprehensively understand TCF4 function and its implications for human disorders. Moreover, the primate-specific expression patterns of TCF4 will inform genetic and other therapeutic strategies to treat TCF4-associated disorders.