cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Breaking the Cycle of Alienation: The Impact of Youth Representation on Democratic Engagement
Creators: name: Kolodziejczyk, Kamila
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2024
Subjects: Youth in politics
Underrepresented groups
Cycle of political alienation
Civic engagement
Satisfaction with democracy
Voting
Young people

description: The underrepresentation of youth in politics fuels a vicious cycle of political alienation. Due to the low presence of youth in political institutions, their specific interests are not adequately represented and therefore policies important to youth are not implemented which leaves youth with feelings of apathy and disconnect to the formal political systems. This research aims to test whether the cycle of political alienation can be broken by increasing youth representation in political institutions. I hypothesize that increased youth representation in parliaments and governments can trigger higher electoral participation and higher satisfaction with democracy from young people. To test my hypotheses, I constructed an original dataset using survey results from the Comparative Study of Electoral Systems (CSES), Worldwide Age Representation in Parliaments (WARP) dataset and I hand-collected data on the age of the country leader. The finished dataset includes information on 59 countries, for over 200 elections and over 200 leader ages from 1996 to 2021. My results derived through bivariate and multivariant statistics reveal that higher youth representation in parliaments slightly increases youth voter turnout and increases youth satisfaction with democracy (for the 35 or under age category). Additionally, the age of elected leaders plays a role in shaping young people's satisfaction with democracy. Although the effect of youth representation on the cycle of alienation is not particularly strong, it is statistically significant. This suggests that increasing youth representation in politics could have broader positive impacts on mitigating the cycle of alienation.
Additional file 1 of Low-density lipoprotein cholesterol and risk of hepatocellular carcinoma: a Mendelian randomization and mediation analysis
Creators: name: Cao, Jiali
name: Wang, Ziwen
name: Zhu, Mengpei
name: Huang, Yumei
name: Jin, Ze
name: Xiong, Zhifan
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Virology

description: Additional file 1.
Targeted Focal Adhesion Kinase Activation in Cardiomyocytes Protects the Heart From Ischemia/Reperfusion Injury
Creators: name: Taylor, J. M.
name: Hakim, Z. S.
name: Mack, C. P.
name: Cheng, Z.
name: Rojas, M.
name: DiMichele, L. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We previously reported that cardiac-restricted deletion of focal adhesion kinase (FAK) exacerbated myocyte death following ischemia/reperfusion (I/R). Here we interrogated whether targeted elevation of myocardial FAK activity could protect the heart from I/R injury.
BRCA1 R1699Q variant displaying ambiguous functional abrogation confers intermediate breast and ovarian cancer risk
Creators: name: Spurdle, A. B.
name: Whiley, P. J.
name: Thompson, B.
name: Feng, B.
name: Healey, S.
name: Brown, M. A.
name: Pettigrew, C.
name: kConFab, .
name: Van Asperen, C. J.
name: Weber, Bernhard H. F.
name: Dutch Belgium UV Consortium, .
name: German Consortium of Hereditary Breast and Ovarian Cancer, .
name: French COVAR group collaborators, .
name: on behalf of the ENIGMA Consortium, .
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: 610 Medizin

description: Background Clinical classification of rare sequence changes identified in the breast cancer susceptibility genes BRCA1 and BRCA2 is essential for appropriate genetic counselling of individuals carrying these variants. We previously showed that variant BRCA1 c.5096G>A p.Arg1699Gln in the BRCA1 transcriptional transactivation domain demonstrated equivocal results from a series of functional assays, and proposed that this variant may confer low to moderate risk of cancer.

Methods Measures of genetic risk (report of family history, segregation) were assessed for 68 BRCA1 c.5096G>A p.Arg1699Gln (R1699Q) families recruited through family cancer clinics, comparing results with 34 families carrying the previously classified pathogenic BRCA1 c.5095C>T p.Arg1699Trp (R1699W) mutation at the same residue, and to 243 breast cancer families with no BRCA1 pathogenic mutation (BRCA-X).

Results Comparison of BRCA1 carrier prediction scores of probands using the BOADICEA risk prediction tool revealed that BRCA1 c.5096G>A p.Arg1699Gln variant carriers had family histories that were less ‘BRCA1-like’ than BRCA1 c.5095C>T p.Arg1699Trp mutation carriers (p<0.00001), but more ‘BRCA1-like’ than BRCA-X families (p=0.0004). Further, modified segregation analysis of the subset of 30 families with additional genotyping showed that BRCA1 c.5096G >A p.Arg1699Gln had reduced penetrance compared with the average truncating BRCA1 mutation penetrance (p=0.0002), with estimated cumulative risks to age 70 of breast or ovarian cancer of 24%.

Conclusions Our results provide substantial evidence that the BRCA1 c.5096G>A p.Arg1699Gln (R1699Q) variant, demonstrating ambiguous functional deficiency across multiple assays, is associated with intermediate risk of breast and ovarian cancer, highlighting challenges for risk modelling and clinical management of patients of this and other potential moderate-risk variants.
The Proteoglycan Syndecan 4 Regulates Transient Receptor Potential Canonical 6 Channels via RhoA/Rho-associated Protein Kinase Signaling
Creators: name: Theilmeier, G.
name: Thilo, F.
name: Liu, Y.
name: Jensen, B. L.
name: Loddenkemper, C.
name: Echtermeyer, F.
name: Tepel, M.
name: Schmidt, A.
name: Gollasch, M.
name: Arendshorst, W. J.
name: Marcussen, N.
name: Jankowski, V.
name: Schulein, R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Syndecan 4 (Sdc4) modulates signal transduction and regulates activity of protein channels. Sdc4 is essential for the regulation of cellular permeability. We hypothesized that Sdc4 may regulate transient receptor potential canonical 6 (TRPC6) channels, a determinant of glomerular permeability, in a RhoA/Rho-associated protein kinase-dependent manner.
Combinatorial Modulus on Boundary of Right-Angled Hyperbolic Buildings
Creators: name: Clais, Antoine
Publisher: name: arXiv
Year: 2014
Subjects: subject: Group Theory (math.GR)
subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 20F67, 20F69, 20E42

description: In this article, we discuss the quasiconformal structure of boundaries of right-angled hyperbolic buildings using combinatorial tools. In particular we exhibit some examples of buildings of dimension 3 and 4 whose boundaries satisfy the combinatorial Loewner property. This property is a weak version of the Loewner property. This is motivated by the fact that the quasiconformal structure of the boundary led to many results of rigidity in hyperbolic spaces since G.D. Mostow. In the case of buildings of dimension 2, many work have been done by M. Bourdon and H. Pajot. In particular, the Loewner property on the boundary permitted them to prove the quasi-isometry rigidity of right-angled Fuchsian buildings.
description: Revised version after referee comments
Elevated Prothrombin Promotes Venous, but Not Arterial, Thrombosis in Mice
Creators: name: Machlus, K. R.
name: Aleman, M. M.
name: Byrnes, J. R.
name: Wolberg, A. S.
name: Walton, B. L.
name: Wang, J.-G.
name: Heisler, M. J.
name: Cooley, B. C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Individuals with elevated prothrombin, including those with the prothrombin G20210A mutation, have increased risk of venous thrombosis. Although these individuals do not have increased circulating prothrombotic biomarkers, their plasma demonstrates increased tissue factor-dependent thrombin generation in vitro. The objectives of this study were to determine the pathologic role of elevated prothrombin in venous and arterial thrombosis in vivo, and distinguish thrombogenic mechanisms in these vessels.
title: Ανάπτυξη δικτυακών εφαρμογών σε περιβάλλον MATLAB : εφαρμογή στην ανάλυση και επεξεργασία σεισμολογικών δεδομένων
title: Development of web applications in MATLAB environment: application in analysis and processing of seismological data
titleType: AlternativeTitle
Creators: name: Σουπιωνάς, Αλέξανδρος
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2022
Subjects: Σεισμολογία
Δημιουργία διαδικτυακών εφαρμογών
MATLAB

description: Στην παρούσα εργασία δημιουργούμε διαδικτυακές εφαρμογές μέσω των εργαλείων του λογισμικού matlab. Τα βασικά εργαλεία που χρησιμοποιούμε είναι το MATLAB App Designer και το MATLAB Web App Compiler που μας βοηθάνε στο σχεδιασμό και τη δημιουργία διαδικτυακών εφαρμογών. Σαν είσοδο κάθε εφαρμογής που δημιουργούμε δέχεται αρχεία σεισμολογικών δεδομένων με σκοπό την ανάλυση, υπολογισμό και τη δημιουργία διαγραμμάτων .Οι εφαρμογές που δημιουργούμε αφορούν τον υπολογισμό του κανονικοποιημενου φάσματος φυσικού χρόνου και τον υπολογισμό της κατανομής Gutenberg-Richter (frequencymagnitude distribution GR-FMD) και b-value.
A Cosmological Solution to Mimetic Dark Matter
Creators: name: Saadi, Hassan
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, a cosmological solution to Mimetic Dark Matter (MDM) for an exponential potential is provided. Then, a solution for the $0-i$ perturbed Einstein's differential equation of MDM is obtained based on an exponential potential that satisfies inflation for some initial conditions. Another general potential is suggested that incorporates inflation too. Then, quantum perturbations are included. The constants in the model can be tuned to be in agreement with the amplitude fluctuation of the cosmic microwave background (CMB) radiation. Finally, the spectral index is calculated for the suggested potentials. Moreover, MDM is shown to be a viable model to produce dark matter, inflation, and CMB's fluctuation.
description: 12 pages
การศึกษาและเตรียมความพร้อมสู่การเป็นองค์การมหาชนของกรมวิทยาศาสตร์บริการ
Creators: name: สมบูรณ์ ศิริสรรหิรัญ
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2022
Subjects: Public Organization
Department of Science Service
Strategic Plan

description: Journal of Politics and Governance, 12, 1, 98-114
Endothelial Acyl-CoA Synthetase 1 Is Not Required for Inflammatory and Apoptotic Effects of a Saturated Fatty Acid-Rich Environment
Creators: name: Kanter, J. E.
name: Barnhart, S.
name: Coleman, R. A.
name: Vivekanandan-Giri, A.
name: Shen, X.
name: Kramer, F.
name: Tsuchiya, K.
name: Gonzalez, O.
name: Kim, F.
name: Li, X.
name: Handa, P.
name: Schaffer, J. E.
name: Pennathur, S.
name: Bornfeldt, K. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Saturated fatty acids, such as palmitic and stearic acid, cause detrimental effects in endothelial cells (ECs) and have been suggested to contribute to macrophage accumulation in adipose tissue and the vascular wall in states of obesity and insulin resistance. Long-chain fatty acids are believed to require conversion into acyl-CoA derivatives to exert most of their detrimental effects, a reaction catalyzed by acyl-CoA synthetases (ACSL). The objective of this study was to investigate the role of ACSL1, an ACSL isoform previously shown to mediate inflammatory effects in myeloid cells, in regulating EC responses to a saturated fatty acid-rich environment in vitro and in vivo.
The Deepwater Horizon Oil Spill Coast Guard Cohort study
Creators: name: Barrett, J.
name: Alexander, M.
name: Christenbury, K.
name: Funk, R.H.
name: Engel, L.S.
name: Weems, L.
name: Rusiecki, J.
name: Schwartz, E.G.
name: Wang, L.
name: Johndrow, D.
Publisher: name: BMJ Publishing Group
Year: 2018

description: A cohort study among Coast Guard personnel involved in the Deepwater Horizon (DWH) oil spill response and non-responders was established to investigate potential acute and longterm health effects from oil spill response work exposures. Results showed positive associations between crude oil exposure and various acute physical symptoms among responders, as well as longer term health effects.
Additional file 1 of Enrichment of human nasopharyngeal bacteriome with bacteria from dust after short-term exposure to indoor environment: a pilot study
Creators: name: Konecna, Eva
name: Videnska, Petra
name: Buresova, Lucie
name: Urik, Milan
name: Smetanova, Sona
name: Smatana, Stanislav
name: Prokes, Roman
name: Lanickova, Barbara
name: Budinska, Eva
name: Klanova, Jana
name: Borilova Linhartova, Petra
Publisher: name: figshare
Year: 2023
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Additional results.
Σχέσεις των Μεγάλων Κομνηνών της Τραπεζούντας με το Μεσαιωνικό Κράτος της Ιβηρίας (Γεωργίας) του Καυκάσου (1204-1461)
Creators: name: Ποζίδου, Λίνα
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2022
Subjects: subject: Βυζαντινή Αυτοκρατορία -- Ιστορία -- Δυναστεία των Κομνηνών
subject: Εκκλησία και κράτος -- Βυζαντινή Αυτοκρατορία -- ιστορία
subject: Ορθόδοξη Ανατολική Εκκλησία -- Ιστορία -- Καύκασος
subject: Αυτοκρατορία της Τραπεζούντας
subject: Βασίλειο της Γεωργίας
subject: Μεγάλοι Κομνηνοί
subject: Βαγρατίδες της Ιβηρίας
subject: Empire of Trebizond
subject: Kingdom of Georgia
subject: Grand Komnenoi
subject: Bagratids of Iberia

description: Στην παρούσα διατριβή εξετάζονται οι πολυετείς και πολύπλευρες σχέσεις που αναπτύχθηκαν από τις αρχές του 13ου έως και περίπου τα μέσα του 15ου αιώνα μεταξύ της Αυτοκρατορίας της Τραπεζούντας και του βασιλείου της Γεωργίας. Δια μέσου της συγκριτικής ανάλυσης των βυζαντινών, γεωργιανών, αρμενικών και ρωσικών πηγών επιδιώξαμε να αναδείξουμε σημαντικές πτυχές των αδιάλειπτων κοινωνικοπολιτικών αλληλεπιδράσεων μεταξύ των δύο όμορων, ομόθρησκων και ομόδοξων βασιλείων σε ένα συνεχώς διευρυνόμενο μουσουλμανικό κόσμο. Η συμμαχία που επικυρώθηκε στις αρχές του 12ου αιώνα μέσω δυναστικού συνοικεσίου μεταξύ του βυζαντινού αυτοκρατορικού οίκου των Κομνηνών και των Βαγρατιδών, ανανεώθηκε στις αρχές του 13ου αιώνα όταν η βασίλισσα της Γεωργίας Θάμαρ αποφάσισε να συνδράμει στην εκστρατεία των Αλεξίου και Δαβίδ Μεγάλων Κομνηνών. Καθ’ όλη τη διάρκεια της εξεταζόμενης περιόδου, οι δύο συμμαχικοί οίκοι, επιδίωκαν να ανανεώνουν συνεχώς τους συμμαχικούς όρους αξιοποιώντας τον θεσμό των δυναστικών συνοικεσίων. Η κορύφωση στη μεταξύ τους συνεργασία επήλθε μετά την άλωση της προστάτιδας δύναμης όλων των χριστιανικών πληθυσμών της Ανατολής, της Κωνσταντινούπολης. Αν και αποδυναμωμένοι από τον εμφύλιο πόλεμο που είχε ξεσπάσει στο πολύπαθο βασίλειο της Γεωργίας, οι γεωργιανοί οίκοι συστρατεύθηκαν με τους Μεγάλους Κομνηνούς στην τελευταία προσπάθεια περιορισμού του ολοένα αυξανόμενου οθωμανικού επεκτατισμού.
Exposure to Oil Spill Chemicals and Lung Function in Deepwater Horizon Disaster Response Workers
Creators: name: Jackson, W.B.
name: Lichtveld, M.Y.
name: Engel, L.S.
name: Stewart, P.A.
name: Sandler, D.P.
name: McGrath, J.A.
name: Gam, K.B.
name: Curry, M.D.
name: Stenzel, M.R.
name: Kwok, R.K.
name: Jensen, R.L.
name: Miller, A.K.
Publisher: name: Lippincott Williams and Wilkins
Year: 2018

description: Objective: The aim of this study was to assess the relationship between total hydrocarbon (THC) exposures attributed to oil spill clean-up work and lung function 1 to 3 years after the Deepwater Horizon (DWH) disaster. Methods: We used data from the GuLF STUDY, a large cohort of adults who worked on response to the DWH disaster and others who were safety trained but did not work. We analyzed data from 6288 workers with two acceptable spirometry tests. We estimated THC exposure levels with a job exposure matrix. We evaluated lung function using the forced expiratory volume in 1second (FEV 1; mL), the forced vital capacity (FVC; mL), and the FEV 1 /FVC ratio (%). Results: Lung function measures did not differ by THC exposure levels among clean-up workers. Conclusion: We did not observe an association between THC exposure and lung function among clean-up workers 1 to 3 years following the DWH disaster.
ปัจจัยที่มีอิทธิพลต่อประสิทธิผลในการนำนโยบายกองทุนพัฒนาบทบาทสตรีไปปฏิบัติ ในจังหวัดอุดรธานี
Creators: name: วันเพ็ญ กองคำ
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2022
Subjects: Affecting Factors
Policy Implementation
The Women Empowerment Fund
Effectiveness

description: Journal of Politics and Governance, 12, 1, 115-132
ปัจจัยที่มีความสัมพันธ์ต่อมุมมองความพิการของนิสิตสาขารัฐประศาสนศาสตร์ วิทยาลัยการเมืองการปกครอง มหาวิทยาลัยมหาสารคาม
Creators: name: จีรวัฒน์ เจริญสุข
Publisher: name: College of Politics and Governance (COPAG), Mahasarakham University
Year: 2022
Subjects: Disability
Perspectives of Disability
Public Administration Students

description: Journal of Politics and Governance, 12, 1, 133-148
Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia
Creators: name: Fouchier, S. W.
name: Kooperberg, C.
name: Barnes, T. A.
name: Charnas, L.
name: Martinelli, N.
name: Orho-Melander, M.
name: Lange, L. A.
name: Erdmann, J.
name: Auer, P. L.
name: Schunkert, H.
name: Jackson, R. D.
name: Peloso, G. M.
name: Gabriel, S.
name: Rader, D. J.
name: Girelli, D.
name: Stitziel, N. O.
name: Reilly, M. P.
name: Samani, N. J.
name: Ardissino, D.
name: Duga, S.
name: Nikpay, M.
name: Watkins, H.
name: Moscoso, A. M.
name: Gigante, B.
name: Farrall, M.
name: Goel, A.
name: Sivapalaratnam, S.
name: de Faire, U.
name: Melander, O.
name: Sjouke, B.
name: McPherson, R.
name: Altshuler, D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Autosomal recessive hypercholesterolemia (ARH) is a rare inherited disorder characterized by extremely high total and low-density lipoprotein cholesterol levels that has been previously linked to mutations in LDLRAP1. We identified a family with ARH not explained by mutations in LDLRAP1 or other genes known to cause monogenic hypercholesterolemia. The aim of this study was to identify the molecular etiology of ARH in this family.
Archiving Experiments: A Time-sharing Experiments for the Social Sciences (TESS) and Roper Center Collaboration
Creators: name: Ko, Jessica
Publisher: name: Zenodo
Year: 2023
Subjects: Data management and archiving
Data curation
Experimental data

description: With over 250 experimental surveys conducted on behalf of faculty and graduate students and full funding from the National Science Foundation (NSF), the Time-sharing Experiments for the Social Sciences (TESS) has been an invaluable resource in the political science community. The Roper Center for Public Opinion Research has worked to archive the past 10 years of this experimental data both at the study level and question level. New features in Roper Center’s archival management software enabled full integration of these surveys into our iPoll database spanning over 75 years of polling, while preserving their distinction as experimental surveys. The curation approach and technology together allow for presentation of independently understandable experimental questions including any images and information the respondents may have been shown. This presentation will include a walkthrough of the experimental database as well as processes involved in archiving experimental data, including the gathering of summary information to allow for independently understandable questions and partnering with outside institutions for data entry.
Flt-1 (Vascular Endothelial Growth Factor Receptor-1) Is Essential for the Vascular Endothelial Growth Factor-Notch Feedback Loop During Angiogenesis
Creators: name: Bautch, V. L.
name: Mouillesseaux, K. P.
name: Chappell, J. C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: OBJECTIVE: Vascular endothelial growth factor (VEGF) signaling induces Notch signaling during angiogenesis. Flt-1/VEGF receptor-1 negatively modulates VEGF signaling. Therefore, we tested the hypothesis that disrupted Flt-1 regulation of VEGF signaling causes Notch pathway defects that contribute to dysmorphogenesis of Flt-1 mutant vessels.

APPROACH AND RESULTS: Wild-type and flt-1(-/-) mouse embryonic stem cell-derived vessels were exposed to pharmacological and protein-based Notch inhibitors with and without added VEGF. Vessel morphology, endothelial cell proliferation, and Notch target gene expression levels were assessed. Similar pathway manipulations were performed in developing vessels of zebrafish embryos. Notch inhibition reduced flt-1(-/-) embryonic stem cell-derived vessel branching dysmorphogenesis and endothelial hyperproliferation, and rescue of flt-1(-/-) vessels was accompanied by a reduction in elevated Notch targets. Surprisingly, wild-type vessel morphogenesis and proliferation were unaffected by Notch suppression, Notch targets in wild-type endothelium were unchanged, and Notch suppression perturbed zebrafish intersegmental vessels but not caudal vein plexuses. In contrast, exogenous VEGF caused wild-type embryonic stem cell-derived vessel and zebrafish intersegmental vessel dysmorphogenesis that was rescued by Notch blockade.

CONCLUSIONS: Elevated Notch signaling downstream of perturbed VEGF signaling contributes to aberrant flt-1(-/-) blood vessel formation. Notch signaling may be dispensable for blood vessel formation when VEGF signaling is below a critical threshold.
Intrinsic electron mobility exceeding 1000 cm$^2$/Vs in multilayer InSe FETs
Creators: name: Sucharitakul, Sukrit
name: Goble, Nicholas J.
name: Kumar, U. Rajesh
name: Sankar, Raman
name: Bogorad, Zachary A.
name: Chou, Fang Cheng
name: Chen, Yit-Tsong
name: Gao, Xuan P. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Graphene-like two-dimensional (2D) materials, not only are interesting for their exotic electronic structure and fundamental electronic transport or optical properties but also, hold promises for device miniaturization down to atomic thickness. As one material belonging to this category, InSe is not only a promising candidate for optoelectronic devices but also has potential for ultrathin field effect transistor (FET) with high mobility transport. In this work, various substrates such as PMMA, bare silicon oxide, passivated silicon oxide, and silicon nitride were used to fabricate multi-layer InSe FET devices. Through back gating and Hall measurement in four-probe configuration, the devices' field effect mobility and intrinsic Hall mobility were extracted at various temperatures to study the material's intrinsic transport behavior and the effect of dielectric substrate. The sample's field effect and Hall mobilities over the range of 77-300K fall in the range of 0.1-2.0$\times$10$^3$ cm$^2$/Vs, which are comparable or better than the state of the art FETs made of 2D transition metal-dichalcogenides.
description: Nano Letters, in press
Supplementary document for Supergrowth and sub-wavelength object imaging - 6587927.pdf
Creators: name: Karmakar, Tathagata
name: Chakraborty, Abhishek
name: Vamivakas, Nickolas
name: Jordan, Andrew
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: Intensity calculations
Exact EGB models for spherical static perfect fluids
Creators: name: Hansraj, Sudan
name: Chilambwe, Brian
name: Maharaj, Sunil D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We obtain a new exact solution to the field equations in the EGB modified theory of gravity for a 5-dimensional spherically symmetric static distribution. By using a transformation, the study is reduced to the analysis of a single second order nonlinear differential equation. In general the condition of pressure isotropy produces a first order differential equation which is an Abel equation of the second kind. An exact solution is found. The solution is examined for physical admissability. In particular a set of constants is found which ensures that a pressure-free hypersurface exists which defines the boundary of the distribution. Additionally the isotropic pressure and the energy density are shown to be positive within the radius of the sphere. The adiabatic sound speed criterion is also satisfied within the fluid ensuring a subluminal sound speed. Furthermore, the weak, strong and dominant conditions hold throughout the distribution. On setting the Gauss-Bonnet coupling to zero, an exact solution for 5-dimensional perfect fluids in the standard Einstein theory is obtained. Plots of the dynamical quantities for the Gauss-Bonnet and the Einstein case reveal that the pressure is unaffected while the the energy density increases under the influence of the Gauss-Bonnet term.
description: 18 pages, Submitted for publication
Self-compassion and clinical eating disorder symptoms: a systematic review
Creators: name: Morgan-Lowes, Katherine L.
name: Thøgersen-Ntoumani, Cecilie
name: Howell, Joel
name: Khossousi, Viyona
name: Egan, Sarah J.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: The aim was to conduct a systematic review of the association between self-compassion and eating disorder symptoms and the efficacy of self-compassion interventions in reducing eating disorder symptoms. A systematic literature search was conducted on Web of Science, PsycINFO, MEDLINE, Scopus, and CINAHL on 29 May 2023. The inclusion criteria were: a) available in English, b) published in a peer-reviewed journal, c) used valid measures of self-compassion and eating disorder symptoms, d) clinical eating disorder populations, and e) treatment with self-compassion intervention components. Exclusion criteria were: unpublished studies, dissertations, or study protocols. Study quality was assessed with the Joanna Briggs Institute Critical Appraisal Checklists. There were 15 studies (n = 991) examining self-compassion and eating disorder symptoms in clinical eating disorder populations, seven of which examined self-compassion interventions (n = 369). Higher self-compassion was associated with lower eating disorder symptoms. There was some evidence for the efficacy of self-compassion interventions in reducing eating disorder symptoms. Preliminary evidence indicates some support for self-compassion interventions; however, further high-quality randomised controlled trials are required with more diverse samples. PROSPERO registration: CRD42020196638. What is already known about this topic:(1) Self-compassion has been receiving increasing attention in eating disorders.(2) Previous meta-analyses suggest that self-compassion interventions are efficacious in reducing disordered eating in non-clinical and clinical populations.(3) Self-compassion interventions have some support in reducing clinical eating disorder symptoms. (1) Self-compassion has been receiving increasing attention in eating disorders. (2) Previous meta-analyses suggest that self-compassion interventions are efficacious in reducing disordered eating in non-clinical and clinical populations. (3) Self-compassion interventions have some support in reducing clinical eating disorder symptoms. What this paper adds:(1) Self-compassion interventions may be helpful for clinical eating disorders.(2) Interventions focused on self-compassion may be particularly efficacious for women with binge eating disorder.(3) Future research is needed to examine self-compassion interventions in more diverse samples. (1) Self-compassion interventions may be helpful for clinical eating disorders. (2) Interventions focused on self-compassion may be particularly efficacious for women with binge eating disorder. (3) Future research is needed to examine self-compassion interventions in more diverse samples.
Malingering psychopathology on the Rorschach task: A scoping review
Creators: name: Pimentel, Ruam
name: Meyer, Gregory
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Personality and Social Contexts
subject: Cognition and Perception
subject: Other Psychology
subject: Psychology
subject: FOS: Psychology
subject: Social and Behavioral Sciences
subject: data analytics
subject: Faking
subject: Malingering
subject: Protocol
subject: Psychopathology
subject: Rorschach
subject: Scoping Review

description: This is a registration of a protocol for a scoping review on malingering psychopathology on the Rorschach task
Lung Function in Oil Spill Response Workers 1-3 Years after the Deepwater Horizon Disaster
Creators: name: Stewart, P.A.
name: Jensen, R.L.
name: Stenzel, M.R.
name: Sandler, D.P.
name: Kwok, R.K.
name: Gam, K.B.
name: Lichtveld, M.Y.
name: Keil, A.P.
name: Miller, A.K.
name: Curry, M.D.
name: Engel, L.S.
name: McGrath, J.A.
name: Jackson, W.B.
Publisher: name: Lippincott Williams and Wilkins
Year: 2018

description: Background: Little is known about the effects of inhalation exposures on lung function among workers involved in the mitigation of oil spills. Our objective was to determine the relationship between oil spill response work and lung function 1-3 years after the Deepwater Horizon (DWH) disaster. Methods: We evaluated spirometry for 7,775 adults living in the Gulf states who either participated in DWH response efforts (workers) or received safety training but were not hired (nonworkers). At an enrollment interview, we collected detailed work histories including information on potential exposure to dispersants and burning oil/gas. We assessed forced expiratory volume in 1 second (FEV 1; mL), forced vital capacity (FVC; mL), and the ratio (FEV 1 /FVC%) for differences by broad job classes and exposure to dispersants or burning oil/gas using multivariable linear and modified Poisson regression. Results: We found no differences between workers and nonworkers. Among workers, we observed a small decrement in FEV 1 (Beta, -71 mL; 95% confidence interval [CI], -127 to -14) in decontamination workers compared with support workers. Workers with high potential exposure to burning oil/gas had reduced lung function compared with unexposed workers: FEV 1 (Beta, -183 mL; 95% CI, -316 to -49) and FEV 1 /FVC (Beta, -1.93%; 95% CI, -3.50 to -0.36), and an elevated risk of having a FEV 1 /FVC in the lowest tertile (prevalence ratio, 1.38; 95% CI, 0.99 to 1.92). Conclusions: While no differences in lung function were found between workers and nonworkers, lung function was reduced among decontamination workers and workers with high exposure to burning oil/gas compared with unexposed workers.
Lysine Acetyltransferase PCAF Is a Key Regulator of Arteriogenesis
Creators: name: Arens, R.
name: van der Pouw Kraan, T. C.
name: Faber, J. E.
name: de Boer, H. C.
name: Hamming, J. F.
name: Nossent, A. Y.
name: Quax, P. H. A.
name: de Vries, M. R.
name: Moore, S. M.
name: Ewing, M. M.
name: Peters, E. A. B.
name: Jukema, J. W.
name: Welten, S. M. J.
name: Bastiaansen, A. J. N. M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Therapeutic arteriogenesis, i.e., expansive remodeling of pre-existing collaterals, using single-action factor therapies has not been as successful as anticipated. Modulation of factors that act as a master switch for relevant gene programs may prove more effective. Transcriptional co-activator P300/CBP-associated factor (PCAF) has histone acetylating activity and promotes transcription of multiple inflammatory genes. Because arteriogenesis is an inflammation-driven process, we hypothesized that PCAF acts as multifactorial regulator of arteriogenesis.
Lyotropic isotropic to columnar phase transition in RNA solutions
Creators: name: Mukherjee, Prabir K.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: RNA oligomers exhibit lyotropic chiral nematic and columnar liquid crystal phases. The lyotropic chiral nematic and columnar phases with special emphasize on the isotropic to columnar phase transition in RNA solutions are described based on Landau theory. A free energy is constructed based on the order parameters to describe the chiral nematic and columnar liquid crystal phases and isotropic to columnar phase transition. The lyotropic isotropic to columnar phase transition is found to be always first order. The birefringence has been calculated in the isotropic phase of isotropic to columnar phase transition. Theoretical observation of the existence of the lyotropic isotropic to columnar phase transition in RNA solutions is confirmed with experimental results.
A Symmetry Approach to Geometric Phase for Quantum Ensembles
Creators: name: Andersson, Ole
name: Heydari, Hoshang
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We use tools from the theory of dynamical systems with symmetries to stratify Uhlmann's standard purification bundle and derive a new connection for mixed quantum states. For unitarily evolving systems, this connection gives rise to the 'interferometric' geometric phase of Sjöqvist et al. [Phys. Rev. Lett. 85 2845 - 2849 (2000)], and for more generally evolving open systems it gives rise to the generalization of the interferometric geometric phase due to Tong et al. [Phys. Rev. Lett. 93 080405 (2004)].
description: 17 pages, 7 figures, accepted version
Serum cholesterol trajectories in the 10 years prior to lymphoma diagnosis
Creators: name: Engel, L.
name: Havstad, S.
name: Divine, G.
name: Wang, Y.
name: Alford, S.H.
name: Janakiraman, N.
name: Cancer Research Network Lymphoma Study Group
name: Fortuny, J.
name: Scholes, D.
name: Roblin, D.
name: Johnson, C.C.
name: Epstein, M.M.
name: Wells, K.
name: Yood, M.U.
name: Chao, C.
name: Habel, L.A.
name: Feigelson, H.S.
Publisher: name: Springer International Publishing
Year: 2018

description: Purpose: Many studies suggest a role for cholesterol in cancer development. Serum cholesterol levels have been observed to be low in newly diagnosed lymphoma cases. The objective of these analyses was to examine the time-varying relationship of cholesterol with lymphomagenesis in the 10 years prior to diagnosis by lymphoma subtype. Methods: Participants were selected from the combined membership of six National Cancer Institute-funded Cancer Research Network health plans from 1998 to 2008, excluding members with human immunodeficiency virus, cancer (except lymphoma), or organ transplants. Incident lymphoma cases within this population were ascertained and matched with up to five controls. Total serum cholesterol, high-density lipoprotein, and low-density lipoprotein were collected from plan databases. Multilevel, multivariable longitudinal models were fit after choosing the best polynomial order by deviance statistics for selected lymphoma histotypes to examine pre-diagnosis cholesterol trajectories: Hodgkin lymphoma (n = 519) and all non-Hodgkin lymphomas combined (n = 12,635) as well as six subtypes of the latter. Results: For all categories, lymphoma cases had statistically significantly lower estimated total serum cholesterol, high-density lipoprotein, and low-density lipoprotein levels than controls in the years prior to diagnosis/index date. Between-group differences were most pronounced 3–4 years prior to diagnosis, when cases’ cholesterol levels declined steeply. Conclusions: This analysis is the first to examine changes in serum cholesterol for a decade prior to lymphoma diagnosis. A drop in cholesterol levels was evident several years before diagnosis. Our results suggest that cholesterol-related pathways have an important relationship with lymphomagenesis and low cholesterol could be a preclinical lymphoma marker.
GRB 140619B: a short GRB from a binary neutron star merger leading to black hole formation
Creators: name: Ruffini, R.
name: Muccino, M.
name: Kovacevic, M.
name: Oliveira, F. G.
name: Rueda, J. A.
name: Bianco, C. L.
name: Enderli, M.
name: Penacchioni, A. V.
name: Pisani, G. B.
name: Wang, Y.
name: Zaninoni, E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We show the existence of two families of short GRBs, both originating from the merger of binary neutron stars (NSs): family-1 with $E_{iso}<10^{52}$ erg, leading to a massive NS as the merged core, and family-2 with $E_{iso}>10^{52}$ erg, leading to a black hole (BH). Following the identification of the prototype GRB 090227B, we present the details of a new example of family-2 short burst: GRB 140619B. From the spectral analysis of the early $\sim0.2$ s, we infer an observed temperature $kT =(324\pm33)$ keV of the $e^+e^-$-plasma at transparency (P-GRB), a theoretically derived redshift $z=2.67\pm0.37$, a total burst energy $E^{tot}_{e^+e^-}=(6.03\pm0.79)\times10^{52}$ erg, a rest-frame peak energy $E_{p,i}=4.7$ MeV, and a baryon load $B=(5.52\pm0.73)\times10^{-5}$. We also estimate the corresponding emission of gravitational waves. Two additional examples of family-2 short bursts are identified: GRB 081024B and GRB 090510, remarkable for its well determined cosmological distance. We show that marked differences exist in the nature of the afterglows of these two families of short bursts: family-2 bursts, leading to BH formation, consistently exhibit high energy emission following the P-GRB emission; family-1 bursts, leading to the formation of a massive NS, should never exhibit high energy emission. We also show that both the families fulfill an $E_{p,i}$--$E_{iso}$ relation with slope $γ=0.59\pm0.07$ and a normalization constant incompatible with the one for long GRBs. The observed rate of such family-2 events is $ρ_0=\left(2.1^{+2.8}_{-1.4}\right)\times10^{-4}$Gpc$^{-3}$yr$^{-1}$.
description: 14 pages, 13 figures, ApJ in press
TA'LIM SIFATI YUQORI BO'LGAN MAMLAKATLARDA UMUMIY O'RTA TA'LIMNING TASHKILIY TUZILISHI
Creators: name: Nasirdinov, Komoliddin
Publisher: name: Zenodo
Year: 2025

description: Xalqaro tajribalarini sinchkovlik va qunt bilan o‘rganish ta’lim tarbiyada qotib qolgan, o‘z dolzarbligini yo‘qotib borayotgan ish shakllari, uslublaridan xalos bo‘lish bilan birga, uni munosib tarzda yangilashda qo‘shimcha boy manbalarga ega bo‘lishning asosidir. Davlatimiz rahbari mamlakatda kadrlar muammosi mavjudligini barcha sohalarga islohotlar sur’atiga mos zamonaviy tizim va kadrlar zarurligini ta’kidlagan bir paytda butun ta’lim tizimini takomillashtirish xalqaro tajribalarni o‘rganishdan boshlanadi. Maktabgacha va umumiy o‘rta ta’lim sifatini ilg‘or xalqaro tajriba va zamon talablari asosida shakllantirish muhim ahamiyat kasb etadi.
Soluble CD14: Genomewide Association Analysis and Relationship to Cardiovascular Risk and Mortality in Older Adults
Creators: name: Reiner, A. P.
name: Lange, E. M.
name: Li, J.
name: Lange, L. A.
name: Jenny, N. S.
name: Tracy, R. P.
name: Ellis, J.
name: Cushman, M.
name: Chaves, P. H. M.
name: Walston, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: CD14 is a glycosylphosphotidylinositol-(GPI)-anchored membrane glycoprotein expressed on neutrophils and monocytes/macrophages that also circulates as a soluble form (sCD14). Despite the well-recognized role of CD14 in inflammation, relatively little is known about the genetic determinants of sCD14 or the relationship of sCD14 to vascular- and aging-related phenotypes.
Post-Newtonian constraints on Lorentz-violating gravity theories with a MOND phenomenology
Creators: name: Bonetti, Matteo
name: Barausse, Enrico
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the post-Newtonian expansion of a class of Lorentz-violating gravity theories that reduce to khronometric theory (i.e. the infrared limit of Horava gravity) in high-acceleration regimes, and reproduce the phenomenology of the modified Newtonian dynamics (MOND) in the low-acceleration, non-relativistic limit. Like in khronometric theory, Lorentz symmetry is violated in these theories by introducing a dynamical scalar field (the "khronon") whose gradient is enforced to be timelike. As a result, hypersurfaces of constant khronon define a preferred foliation of the spacetime, and the khronon can be thought of as a physical absolute time. The MOND phenomenology arises as a result of the presence, in the action, of terms depending on the acceleration of the congruence orthogonal to the preferred foliation. We find that if the theory is forced to reduce exactly to General Relativity (rather than to khronometric theory) in the high-acceleration regime, the post-Newtonian expansion breaks down at low accelerations, and the theory becomes strongly coupled. Nevertheless, we identify a sizeable region of the parameter space where the post-Newtonian expansion remains perturbative for all accelerations, and the theory passes both solar-system and pulsar gravity tests, besides producing a MOND phenomenology for the rotation curves of galaxies. We illustrate this explicitly with a toy model of a system containing only baryonic matter but no Dark Matter.
description: 17 pages, 2 figures; includes corrections listed in erratum submitted to PRD (i.e. typos corrected in a few equations; results unchanged)
A Brief Etymology of the Collateral Circulation
Creators: name: Simons, M.
name: Deindl, E.
name: van Royen, N.
name: Chilian, W. M.
name: Faber, J. E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: It is well known that the protective capacity of the collateral circulation falls short in many individuals with ischemic disease of the heart, brain and lower extremities. In the past fifteen years, opportunities created by molecular and genetic tools, together with disappointing outcomes in many “angiogenic” trials, has led to a significant increase in the number of studies that focus on: 1) understanding the basic biology of the collateral circulation; 2) identifying the mechanisms that limit the collateral circulation’s capacity in many individuals; 3) devising methods to measure collateral extent, which has been found to vary widely among individuals; and 4) developing treatments to increase collateral blood flow in obstructive disease. Unfortunately, accompanying this increase in reports has been a proliferation of vague terms used to describe the disposition and behavior of this unique circulation, as well as the increasing miss-use of well-ensconced ones by new (and old) students of the collateral circulation. With this in mind, we provide a brief glossary of readily understandable terms to denote the formation, adaptive growth, and mal-adaptive rarefaction of the collateral circulation. We also propose terminology for several newly discovered processes that occur in the collateral circulation. Finally, we include terms used to describe vessels that are sometimes confused with collaterals, as well as terms describing processes active in the general arterial-venous circulation when ischemic conditions engage the collateral circulation. We hope this brief review will help unify the terminology used in collateral research.
title: I nuovi confini del lavoro: la trasformazione digitale
Creators: name: Lunardon, Fiorella
name: Menegatti, Emanuele
Publisher: name: Department of Sociology and Business Law
Year: 2024

description: Il volume si pone l'obiettivo di approfondire il tema delle trasformazioni digitali nel mondo del lavoro da diverse prospettive di analisi. Propone molteplici spunti di riflessione circa il ruolo giocato dal legislatore nella regolamentazione del fenomeno, ma anche dalle parti sociali e dai lavoratori, verso una transizione digitale giusta. La lettura del fenomeno proposta, che si colloca in una visione antropocentrica, sostenibile e resiliente, consente un approccio innovativo alle questioni sottese alla digitalizzazione del lavoro.
Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-Oxide, a Proatherogenic Metabolite of Choline and L-Carnitine
Creators: name: Tang, W. H. W.
name: Allayee, H.
name: Lusis, A. J.
name: Roberts, R.
name: McPherson, R.
name: Wang, Z.
name: Bennett, B. J.
name: Stewart, A. F. R.
name: Hartiala, J.
name: Hazen, S. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Elevated levels of plasma trimethyl amine N-oxide (TMAO), the product of gut microbiome and hepatic-mediated metabolism of dietary choline and L-carnitine, have recently been identified as a novel risk factor for the development of atherosclerosis in mice and humans. The goals of this study were to identify the genetic factors associated with plasma TMAO levels.