title: Ð Ð¾Ð»Ñ Ð°Ð´ÑÐµÐ½Ð¾ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ¾Ð² Ð² Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸ÑÑ Ð»ÑÐ³Ð¾ÑÐ½Ð¾Ð¹ Ð³ÐµÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ Ð¿ÑÐ¸ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð¾Ð¹ Ð¸ÑÐµÐ¼Ð¸Ð¸ Ð¼Ð¸Ð¾ÐºÐ°ÑÐ´Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: The role of adrenergic receptors in changes in pulmonary hemodynamics in experimental myocardial ischemia
Creators: name: ÐÑÐ·Ð½ÐµÑÐ¾Ð²Ð°, ÐÐ½Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: Ð°Ð´ÑÐµÐ½Ð¾ÑÐµÑÐµÐ¿ÑÐ¾ÑÑ
Ð¸ÑÐµÐ¼Ð¸Ñ Ð¼Ð¸Ð¾ÐºÐ°ÑÐ´Ð°
ÑÐµÐ½ÑÐ¾Ð»Ð°Ð¼Ð¸Ð½
Ð¿ÑÐ¾Ð¿ÑÐ°Ð½Ð¾Ð»Ð¾Ð»
Ð°Ð»ÑÑÐ°-Ð±Ð»Ð¾ÐºÐ°Ð´Ð°
Ð±ÐµÑÐ°-Ð±Ð»Ð¾ÐºÐ°Ð´Ð°
Ð»ÑÐ³Ð¾ÑÐ½Ð°Ñ Ð³ÐµÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ°
adrenoreceptors
myocardial ischemia
phentolamine
propranolol
alpha blockade
beta blockade
pulmonary hemodynamics

description: Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑÑÑ ÑÐ¾Ð»Ñ Ð°Ð´ÑÐµÐ½ÐµÑÐ³Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ¾Ð² Ð² Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸ÑÑ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² Ð»ÐµÐ³Ð¾ÑÐ½Ð¾Ð¹ Ð³ÐµÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ Ð¿ÑÐ¸ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð¾Ð¹ Ð¼Ð¸Ð¾ÐºÐ°ÑÐ´Ð¸Ð°Ð»ÑÐ½Ð¾Ð¹ Ð¸ÑÐµÐ¼Ð¸Ð¸ Ñ ÐºÑÐ¾Ð»Ð¸ÐºÐ¾Ð² Ñ Ð°Ð»ÑÑÐ°-Ð°Ð´ÑÐµÐ½ÐµÑÐ³Ð¸ÑÐµÑÐºÐ¸Ð¼Ð¸ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ°Ð¼Ð¸, Ð±Ð»Ð¾ÐºÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼Ð¸ ÑÐµÐ½ÑÐ¾Ð»Ð°Ð¼Ð¸Ð½Ð¾Ð¼, Ð¸ Ð±ÐµÑÐ°-Ð°Ð´ÑÐµÐ½ÐµÑÐ³Ð¸ÑÐµÑÐºÐ¸Ð¼Ð¸ ÑÐµÑÐµÐ¿ÑÐ¾ÑÐ°Ð¼Ð¸, Ð±Ð»Ð¾ÐºÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÐ¼Ð¸ Ð¿ÑÐ¾Ð¿ÑÐ°Ð½Ð¾Ð»Ð¾Ð»Ð¾Ð¼, Ð¸ Ð¿Ð¾ÑÐ»ÐµÐ´ÑÑÑÐ¸Ð¼ ÑÑÐ°Ð²Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÐ¼ Ð°Ð½Ð°Ð»Ð¸Ð·Ð¾Ð¼. ÐÑÐ»Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ñ Ð´Ð²Ðµ ÑÐµÑÐ¸Ð¸ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ¾Ð². ÐÐ½Ð°ÑÐ°Ð»Ðµ Ñ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÑ Ð²ÑÐ·ÑÐ²Ð°Ð»Ð°ÑÑ Ð¸ÑÐµÐ¼Ð¸Ñ Ð¼Ð¸Ð¾ÐºÐ°ÑÐ´Ð°. ÐÐ¾ÑÐ»Ðµ ÑÑÐ¾Ð³Ð¾ Ð¼Ñ Ð¶Ð´Ð°Ð»Ð¸ ÑÑÐ°Ð±Ð¸Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð³ÐµÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ Ð¿Ð°-ÑÐ°Ð¼ÐµÑÑÐ¾Ð². Ð Ð¿ÐµÑÐ²Ð¾Ð¹ ÑÐµÑÐ¸Ð¸ Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÐ¼ Ð²Ð²Ð¾Ð´Ð¸Ð»Ð¸ ÑÐµÐ½ÑÐ¾Ð»Ð°Ð¼Ð¸Ð½ Ð² Ð»ÐµÐ²ÑÑ ÑÑÐµÐ¼Ð½ÑÑ Ð²ÐµÐ½Ñ, Ð¸ÑÐµÐ¼Ð¸Ñ Ð¼Ð¸Ð¾ÐºÐ°ÑÐ´Ð° ÑÐ½Ð¾Ð²Ð° Ð²ÑÐ·ÑÐ²Ð°Ð»Ð°ÑÑ. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¹ ÑÐµÑÐ¸Ð¸ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ° Ð¶Ð¸Ð²Ð¾ÑÐ½ÑÐ¼ Ð²Ð²Ð¾Ð´Ð¸Ð»Ð¸ Ð±ÐµÑÐ°-Ð°Ð´ÑÐµÐ½Ð¾Ð±Ð»Ð¾ÐºÐ°ÑÐ¾Ñ Ð¿ÑÐ¾Ð¿ÑÐ°Ð½Ð¾Ð»Ð¾Ð». ÐÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°Ð»Ð¾, ÑÑÐ¾ ÑÐ°Ð·Ð»Ð¸ÑÐ¸Ñ Ð² Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸ÑÑ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² Ð³ÐµÐ¼Ð¾Ð´Ð¸Ð½Ð°Ð¼Ð¸ÐºÐ¸ Ð² Ð»ÐµÐ³Ð¾ÑÐ½Ð¾Ð¹ Ð°ÑÑÐµÑÐ¸Ð¸ Ð²Ð¾ Ð²ÑÐµÐ¼Ñ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð¾Ð¹ Ð¼Ð¸Ð¾ÐºÐ°ÑÐ´Ð¸Ð°Ð»ÑÐ½Ð¾Ð¹ Ð¸ÑÐµÐ¼Ð¸Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÑÑÑÑÑ Ð½Ðµ ÑÐ¾Ð»ÑÐºÐ¾ Ð¿ÑÑÐ¼ÑÐ¼ Ð²Ð»Ð¸ÑÐ½Ð¸ÐµÐ¼ Ð±Ð»Ð¾ÐºÐ°Ð´Ñ, Ð½Ð¾ Ð¸ Ð¸Ð·Ð¼ÐµÐ½ÐµÐ½Ð¸ÑÐ¼Ð¸ Ð´ÑÑÐ³Ð¸Ñ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð², Ð²ÑÐ·Ð²Ð°Ð½Ð½ÑÐ¼Ð¸ ÑÑÐ¾Ð¹ Ð±Ð»Ð¾ÐºÐ°Ð´Ð¾Ð¹. ÐÐ¾Ð»ÑÑÐµÐ½Ð½ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¼Ð¾Ð³ÑÑ Ð±ÑÑÑ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ñ Ð¿ÑÐ¸ Ð²ÑÐ±Ð¾ÑÐµ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² ÐºÐ¾ÑÑÐµÐºÑÐ¸Ð¸ Ð½Ð°ÑÑÑÐµÐ½Ð¸Ð¹ Ð² ÑÐ°Ð±Ð¾ÑÐµ ÑÐ¸ÑÑÐµÐ¼Ñ ÐºÑÐ¾Ð²Ð¾Ð¾Ð±ÑÐ°ÑÐµÐ½Ð¸Ñ.
description: The given work is devoted to the study of the role of adrenergic receptors in changes of pulmonary hemodynamics parameters during experimental myocardial ischemia in rabbits with alpha-adrenergic receptors blocked by phentolamine and beta-adrenergic receptors blocked by propranolol and to the subsequent comparative analysis. Two series of experiments were conducted. In the beginning, myocardial ischemia was induced in animals. After this, we waited until the stabilization of hemodynamic parameters. In the first series, the animals were injected with phentolamine in the left jugular vein and myocardial ischemia was induced again. In the second series of the experiment, the animals were injected with the beta-blocker propranolol. The study found that the differences in changes of hemodynamic parameters in the pulmonary artery during experimental myocardial ischemia are determined not only by the direct influence of the blockade, but also by the changes in other parameters caused by this blockade. The results can be applied by choosing methods for correction of circulatory system disorders.