cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
Creators: name: Lefkowitz, Robert J.
name: Bond, Richard A.
name: Johnson, T. David
name: Kenakin, Terry P.
name: Milano, Caremlo A.
name: McMinn, Thomas R.
name: Allen, Lee F.
name: Leff, Paul
name: Rockman, Howard A.
name: Hyek, Michael F.
name: Apparsundaram, Subramaniam
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1995

description: G-PROTEIN-COUPLED receptors are thought to have an inactive conformation (R), requiring an agonist-induced conformational change for receptor/G-protein coupling1–3. But new evidence suggests a two-state model4–19 in which receptors are in equilibrium between the inactive conformation (R), and a spontaneously active conformation (R*) that can couple to G protein in the absence of ligand (Fig. 1). Classic agonists have a high affinity for R* and increase the concentration of R*, whereas inverse agonists have a high affinity for R and decrease the concentration of R*. Neutral competitive antagonists have equal affinity for R and R* and do not displace the equilibrium, but can competitively antagonize the effects both of agonists and of inverse agonists. The lack of suitable in vivo model systems has restricted the evidence for the existence of inverse agonists to computer simulations7,8 and in vitro systems5,9–12,20–23. We have used a transgenic mouse model in which there is such marked myocardial overexpression of β2-adrenoceptors that a significant population of spontaneously activated receptor (R*) is present, inducing a maximal response without agonist24. We show that the β2-adrenoceptor ligand ICI-118,551 functions as an inverse agonist, providing evidence supporting the existence of inverse agonists and validating the two-state model of G-protein-coupled receptor activation.
АНАЛИЗ НА СЪДЪРЖАНИЕТО НА НОВОПРИЕТАТА ЕВРОПЕЙСКА НОМЕНКЛАТУРА НА МЕДИЦИНСКИ ИЗДЕЛИЯ
Creators: name: Petkova, Paola
name: Grigorov, Evgeni
name: Salchev, Petko
name: Getov, Ilko
Publisher: name: Zenodo
Year: 2023

description: Проучването има за цел да установи цялостно разбиране на ролята на Европейската номенклатура на медицинските изделия (EMDN) в регулирането, регистрацията и проследимостта на медицинските изделия на европейския пазар, включително неговите предимства и ограничения
Проучването съдържа задълбочено изследване на Европейската номенклатура на медицинските изделия (EMDN), достъпна на публичния уебсайт EUDAMED.
Европейската номенклатура на медицинските изделия (EMDN) е пусната за първи път на 4 май 2021 г. в съответствие с чл. 26 от Регламент (ЕС) 2017/745 относно медицинските изделия (MDR). EMDN служи като поддържащ механизъм за работата на Европейската база данни за медицински изделия (EUDAMED), като свързва всеки уникален идентификатор на устройство – идентификатор на устройство (UDI-DI) с регистрацията на производителя на медицински изделия. EMDN е структурирана в съответствие с принципите, определени от Европейската комисия - структуриране, предвидимост, прозрачност, приобщаване, достъпност и международност. Тя използва буквено-цифрова структура с йерархично дърво от седем нива, категоризирайки медицинските устройства в три основни нива: Категории, Групи и Типове, с допълнителни нива на детайлност, ако е необходимо. Буквено-цифровите кодове започват с буква, представляваща „КАТЕГОРИЯТА“, последвана от две цифри, указващи „ГРУПАТА“, и поредица от цифри, представляващи „ТИП“. Максималният брой цифри е зададен на 13.
On the ensemble dependence in black hole geometrothermodynamics
Creators: name: Quevedo, Hernando
name: Sanchez, Alberto
name: Taj, Safia
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We investigate the dependence of thermodynamic properties of black holes on the choice of statistical ensemble for a particular class of Einstein-Maxwell-Gauss-Bonnet black holes with cosmological constant. We use partial Legendre transformations in the thermodynamic limit in order to compare the results in different ensembles, and show that the phase transition structure depend on the choice of thermodynamic potential. This result implies that thermodynamic metrics which are partially Legendre invariant cannot be employed to describe black hole thermodynamics, and partly explains why a particular thermodynamic metric has been used so far in the framework of black hole geometrothermodynamics.
description: 14 pages, no figures
The barrier function of CYP3A4 and P-glycoprotein in the small bowel
Creators: name: Watkins, Paul
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1997

description: CYP3A4 present in small bowel enterocytes can catalyze substantial metabolism of some orally administered drugs and, thus, exerts a first-pass effect. Recent data indicate that the P-glycoprotein (the MDR 1 gene product) in the enterocyte brush border also limits the bioavailability of many of the same drugs that interact with CYP3A. It has been proposed that P-glycoprotein and CYP3A4 may be functionally linked because (a) the two proteins are co-localized within the digestive tract and within enterocytes, (b) they share many of the same substrates and (c) they are co-inducible in response to at least some xenobiotics. There are several potential mechanisms whereby the functions of P-glycoprotein and CYP3A4 could be complimentary. First, Pgp may limit absorption in the proximal small bowel, shifting it to more distal, less catalytically efficient segments that contain lower amounts of CYP3A4. Second, Pgp may function to prolong the duration of absorption. This might increase the duration of exposure of drug to and, hence, the extent of metabolism by enterocyte CYP3A4. Finally, Pgp may preferentially remove from the enterocyte primary drug metabolites that are themselves substrates for CYP3A4. This would limit product inhibition and facilitate primary metabolism catalyzed by CYP3A4. Characterization of the roles of CYP3A4 and Pgp in limiting oral drug availability may be aided by recent success in the development of human intestinal cell lines that stably express both CYP3A4 and Pgp.
NPOI Observations of the Exoplanet Host kappa Coronae Borealis and Their Implications for the Star's and Planet's Masses and Ages
Creators: name: Baines, Ellyn K.
name: Armstrong, J. Thomas
name: van Belle, Gerard T.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We used the Navy Precision Optical Interferometer to measure the limb-darkened angular diameter of the exoplanet host star kappa CrB and obtained a value of 1.543 +/- 0.009 mas. We calculated its physical radius (5.06 +/- 0.04 R_Sun) and used photometric measurements from the literature with our diameter to determine kappa CrB's effective temperature (4788 +/- 17 K) and luminosity (12.13 +/- 0.09 L_Sun). We then placed the star on an H-R diagram to ascertain the star's age (3.42 +0.32/-0.25 Gyr) and mass (1.47 +/- 0.04 M_Sun) using a metallicity of [Fe/H] = +0.15. With this mass, we calculated the system's mass function with the orbital elements from a variety of sources, which produced a range of planetary masses: m_p sin i = 1.61 to 1.88 M_Jup. We also updated the extent of the habitable zone for the system using our new temperature.
description: 13 pages, 2 figures, 2 tables; accepted for publication in the Astrophysical Journal Letters
Asymmetric Diffusion of Magnetic Field Lines
Creators: name: Beresnyak, Andrey
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Stochasticity of magnetic field lines is important for particle transport properties. Magnetic field lines separate faster than diffusively in turbulent plasma, which is called superdiffusion. We discovered that this superdiffusion is pronouncedly asymmetric, so that the separation of field lines along the magnetic field direction is different from the separation in the opposite direction. While the symmetry of the flow is broken by the so-called imbalance or cross-helicity, the difference between forward and backward diffusion is not directly due to imbalance, but a non-trivial consequence of both imbalance and non-reversibility of turbulence. The asymmetric diffusion perpendicular to the mean magnetic field entails a variety of new physical phenomena, such as the production of parallel particle streaming in the presence of perpendicular particle gradients. Such streaming and associated instabilities could be significant for particle transport in laboratory, space and astrophysical plasmas.
description: 4 pages 3 figures
Five-year trends in epidemiology and prevention of mother-to-child HIV transmission, St. Petersburg, Russia: results from perinatal HIV surveillance
Creators: name: Voronin, Evgeny E
name: Volkova, Galina V
name: Miller, William
name: Rakhmanova, Aza G
name: Vitek, Charles
name: Robinson, Joanna
name: Jamieson, Denise J
name: Mandel, Michele G
name: Belyakov, Nikolay A
name: Yakovlev, Alexey A
name: Kissin, Dmitry M
name: Hillis, Susan
name: Akatova, Natalia
Publisher: name: BioMed Central Ltd
Year: 2011

description: Abstract Background The HIV epidemic in Russia has increasingly involved reproductive-aged women, which may increase perinatal HIV transmission. Methods Standard HIV case-reporting and enhanced perinatal HIV surveillance systems were used for prospective assessment of HIV-infected women giving birth in St. Petersburg, Russia, during 2004-2008. Trends in social, perinatal, and clinical factors influencing mother-to-child HIV transmission stratified by history of injection drug use, and rates of perinatal HIV transmission were assessed using two-sided χ2 or Cochran-Armitage tests. Results Among HIV-infected women who gave birth, the proportion of women who self-reported ever using injection drugs (IDUs) decreased from 62% in 2004 to 41% in 2008 (P < 0.0001). Programmatic improvements led to increased uptake of the following clinical services from 2004 to 2008 (all P < 0.01): initiation of antiretroviral prophylaxis at ≤28 weeks gestation (IDUs 44%-54%, non-IDUs 45%-72%), monitoring of immunologic (IDUs 48%-64%, non-IDUs 58%-80%) and virologic status (IDUs 8%-58%, non-IDUs 10%-75%), dual/triple antiretroviral prophylaxis (IDUs 9%-44%, non-IDUs 14%-59%). After initial increase from 5.3% (95% confidence interval [CI] 3.5%-7.8%) in 2004 to 8.5% (CI 6.1%-11.7%) in 2005 (P < 0.05), perinatal HIV transmission decreased to 5.3% (CI 3.4%-8.3%) in 2006, and 3.2% (CI 1.7%-5.8%) in 2007 (P for trend <0.05). However, the proportion of women without prenatal care and without HIV testing before labor and delivery remained unchanged. Conclusions Reduced proportion of IDUs and improved clinical services among HIV-infected women giving birth were accompanied by decreased perinatal HIV transmission, which can be further reduced by increasing outreach and HIV testing of women before and during pregnancy.
Rubus sulcatus Vest
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: R. sulcatus Vest l: Les Combasses bei Salvan (Coquoz);Finhaut (Schmidely).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Risperidone-induced Premature Ventricular Complexes in Psychosis: A Case Report
Creators: name: SIDDIQUI, JAVED ATHER
name: QURESHI, SHAZIA FARHEEN
Publisher: name: figshare
Year: 2023
Subjects: Other health sciences not elsewhere classified

description: Atypical antipsychotics are known to cause cardiovascular side efects, such as prolonging the QTc interval due to blockade of the potassium repolarization channels, and hence they predispose to ventricular arrhythmias, like premature ventricular complexes (PVCs). Here, we report a case of a male schizophrenic patient who is complaining of palpitations and feeling clinically as well as symptomatically troublesome PVCs associated with risperidone. We consider that PVCs may have been generated by risperidone, with his stressful mental condition, and subsided after withholding it.
On Poynting-Flux-Driven Bubbles and Shocks Around Merging Neutron Star Binaries
Creators: name: Medvedev, M. V.
name: Loeb, A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Merging binaries of compact relativistic objects (neutron stars and black holes) are thought to be progenitors of short gamma-ray bursts and sources of gravitational waves, hence their study is of great importance for astrophysics. Because of the strong magnetic field of one or both binary members and high orbital frequencies, these binaries are strong sources of energy in the form of Poynting flux (e.g., magnetic-field-dominated outflows, relativistic leptonic winds, electromagnetic and plasma waves). The steady injection of energy by the binary forms a bubble (or a cavity) filled with matter with the relativistic equation of state, which pushes on the surrounding plasma and can drive a shock wave in it. Unlike the Sedov-von Neumann-Taylor blast wave solution for a point-like explosion, the shock wave here is continuously driven by the ever-increasing pressure inside the bubble. We calculate from the first principles the dynamics and evolution of the bubble and the shock surrounding it and predict that such systems can be observed as radio sources a few hours before and after the merger. At much later times, the shock is expected to settle onto the Sedov-von Neumann-Taylor solution, thus resembling an explosion.
description: 18 pages, 2 figures
The Association between Hyponatremia and Psychotropic: An Observational Study in Chronic Forensic Rehabilitation Ward at Mental Health Hospital, Taif, Saudi Arabia
Creators: name: SIDDIQUI, JAVED ATHER
name: QURESHI, SHAZIA FARHEEN
Publisher: name: figshare
Year: 2023
Subjects: Other health sciences not elsewhere classified

description: Background: Hyponatremia is the most common electrolyte imbalance experienced in psychiatric clinical practice, both in hospital and outpatient settings, in patients taking psychotropic medications. It is a multifactorial clinical condition characterized by a plasma sodium level of less than 130 millimoles per liter. In psychiatric patients, this is mostly ignored and untreated, which can lead to increased mortality.1 Aims and objectives: The main objectives of this study are: • To evaluate the socio-demographic profile. • To evaluate the severity of hyponatremia in patients using psychotropic. • To evaluate the association between hyponatremia and psychotropic. Materials and methods: This was an observational study performed in the forensic psychiatric rehabilitation wards of the Mental Health Hospital, Taif, Saudi Arabia. Study participants were patients admitted to the inpatient ward (n = 73) between 2018 and 2022. Descriptive statistical analysis was explored and presented as categorical variables such as frequencies and percentages. We also explored the relationship between hyponatremia and psychotropics. Results: An observational study was conducted over a period of 5 years. The majority of patients (34.48%) were in the age group of 46 to 55 years, and the total number of hyponatremia patients was (n= 29; 39.72%). The maximum number of patients was 44.82% with mild hyponatremia (130–134 mmol/L), 37.93% with moderate (125–130 mmol/L), and 17.24% with severe hyponatremia (<120 mmol/L). Hyponatremia was found in 4.10% of antidepressant patients, 20.54% of patients on antipsychotics, and 9.58% of patients on mood stabilizers. Conclusions: In our study, hyponatremia was most prevalent among patients between 45 and 55 years of age. Haloperidol was the most likely antipsychotic to cause hyponatremia. Among atypical antipsychotics, aripiprazole was most commonly associated with hyponatremia, followed by risperidone and amisulpride, whereas quetiapine had a minimal number. Among mood stabilizers, valproic acid was associated with hyponatremia, whereas lithium and carbamazepine were less likely to be associated.
Comprehensive molecular portraits of human breast tumours
Creators: name: Perou, Charles
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase protein arrays. Our ability to integrate information across platforms provided key insights into previously defined gene expression subtypes and demonstrated the existence of four main breast cancer classes when combining data from five platforms, each of which shows significant molecular heterogeneity. Somatic mutations in only three genes (TP53, PIK3CA and GATA3) occurred at >10% incidence across all breast cancers; however, there were numerous subtype-associated and novel gene mutations including the enrichment of specific mutations in GATA3, PIK3CA and MAP3K1with the luminal A subtype. We identified two novel protein-expression-defined subgroups, possibly produced by stromal/microenvironmental elements, and integrated analyses identified specific signalling pathways dominant in each molecular subtype including a HER2/phosphorylated HER2/EGFR/phosphorylated EGFR signature within the HER2-enriched expression subtype. Comparison of basal-like breast tumours with high-grade serous ovarian tumours showed many molecular commonalities, indicating a related aetiology and similar therapeutic opportunities. The biological finding of the four main breast cancer subtypes caused by different subsets of genetic and epigenetic abnormalities raises the hypothesis that much of the clinically observable plasticity and heterogeneity occurs within, and not across, these major biological subtypes of breast cancer.
Hard-core bosons in one-dimensional interacting topological bands
Creators: name: Guo, Huaiming
Publisher: name: arXiv
Year: 2013
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study the hard-core bosons in one-dimensional (1D) interacting topological bands at different filling factors using exact diagonalization. At the filling factor $ν=1$ and in the presence of on-site Hubbard interaction, we find no sign of the existence of the bosonic topological phase, which is in contrast to the fermionic case. Instead by studying the momentum distribution and the condensate fraction we find a superfluid (SF) to Mott-insulator transition driven by the Hubbard interaction. At the filling factor $ν=1/3$ and in the presence of longer-ranged interactions, we identify the bosonic fractional topological phase (FTP) whose ground-states are characterized by the three-fold degeneracy and quantized total Berry phase, which is very similar to the fermionic case. Finally we discuss the reason of the different behaviors of hard-core bosons at different filling factors by mapping them to spinless fermions. Our these results can be realized in cold-atom experiments.
description: PHYSICAL REVIEW A 86, 055604 (2012), brief report
ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction)
Creators: name: Smith, Sidney C., Jr.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: "The ACC/AHA Task Force on Practice Guidelines was formed to make recommendations regarding the diagnosis and treatment of patients with known or suspected cardiovascular disease (CVD). Coronary artery disease (CAD) is the leading cause of death in the United States. Unstable angina (UA) and the closely related condition of non–ST-segment elevation myocardial infarction (NSTEMI) are very common manifestations of this disease. The committee members reviewed and compiled published reports through a series of computerized literature searches of the English-language literature since 2002 and a final manual search of selected articles. Details of the specific searches conducted for particular sections are provided when appropriate. Detailed evidence tables were developed whenever necessary with the specific criteria outlined in the individual sections. The recommendations made were based primarily on these published data. The weight of the evidence was ranked highest (A) to lowest (C). The final recommendations for indications for a diagnostic procedure, a particular therapy, or an intervention in patients with UA/NSTEMI summarize both clinical evidence and expert opinion."
Discrete Quantum Theories
Creators: name: Hanson, Andrew J.
name: Ortiz, Gerardo
name: Sabry, Amr
name: Tai, Yu-Tsung
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We explore finite-field frameworks for quantum theory and quantum computation. The simplest theory, defined over unrestricted finite fields, is unnaturally strong. A second framework employs only finite fields with no solution to x^2+1=0, and thus permits an elegant complex representation of the extended field by adjoining i=\sqrt{-1}. Quantum theories over these fields recover much of the structure of conventional quantum theory except for the condition that vanishing inner products arise only from null states; unnaturally strong computational power may still occur. Finally, we are led to consider one more framework, with further restrictions on the finite fields, that recovers a local transitive order and a locally-consistent notion of inner product with a new notion of cardinal probability. In this framework, conventional quantum mechanics and quantum computation emerge locally (though not globally) as the size of the underlying field increases. Interestingly, the framework allows one to choose separate finite fields for system description and for measurement: the size of the first field quantifies the resources needed to describe the system and the size of the second quantifies the resources used by the observer. This resource-based perspective potentially provides insights into quantitative measures for actual computational power, the complexity of quantum system definition and evolution, and the independent question of the cost of the measurement process.
description: 13 pages. Submitted to Physical Review A
Protein co-expression network analysis (ProCoNA)
Creators: name: Baric, Ralph S.
Publisher: name: BioMed Central Ltd
Year: 2013

description: Abstract Background Biological networks are important for elucidating disease etiology due to their ability to model complex high dimensional data and biological systems. Proteomics provides a critical data source for such models, but currently lacks robust de novo methods for network construction, which could bring important insights in systems biology. Results We have evaluated the construction of network models using methods derived from weighted gene co-expression network analysis (WGCNA). We show that approximately scale-free peptide networks, composed of statistically significant modules, are feasible and biologically meaningful using two mouse lung experiments and one human plasma experiment. Within each network, peptides derived from the same protein are shown to have a statistically higher topological overlap and concordance in abundance, which is potentially important for inferring protein abundance. The module representatives, called eigenpeptides, correlate significantly with biological phenotypes. Furthermore, within modules, we find significant enrichment for biological function and known interactions (gene ontology and protein-protein interactions). Conclusions Biological networks are important tools in the analysis of complex systems. In this paper we evaluate the application of weighted co-expression network analysis to quantitative proteomics data. Protein co-expression networks allow novel approaches for biological interpretation, quality control, inference of protein abundance, a framework for potentially resolving degenerate peptide-protein mappings, and a biomarker signature discovery.
Tests of the asymptotic large frequency separation of acoustic oscillations in solar-type and red giant stars
Creators: name: Hekker, S.
name: Elsworth, Y.
name: Basu, S.
name: Mazumdar, A.
name: Aguirre, V. Silva
name: Chaplin, W. J.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Asteroseismology, i.e. the study of the internal structures of stars via their global oscillations, is a valuable tool to obtain stellar parameters such as mass, radius, surface gravity and mean density. These parameters can be obtained using certain scaling relations which are based on an asymptotic approximation. Usually the observed oscillation parameters are assumed to follow these scaling relations. Recently, it has been questioned whether this is a valid approach, i.e., whether the order of the observed oscillation modes are high enough to be approximated with an asymptotic theory. In this work we use stellar models to investigate whether the differences between observable oscillation parameters and their asymptotic estimates are indeed significant. We compute the asymptotic values directly from the stellar models and derive the observable values from adiabatic pulsation calculations of the same models. We find that the extent to which the atmosphere is included in the models is a key parameter. Considering a larger extension of the atmosphere beyond the photosphere reduces the difference between the asymptotic and observable values of the large frequency separation. Therefore, we conclude that the currently suggested discrepancies in the scaling relations might have been overestimated. Hence, based on the results presented here we believe that the suggestions of Mosser et al. (2013) should not be followed without careful consideration.
description: 6 pages, 4 figures, 1 table, accepted for publication by MNRAS as a Letter to the Editor
A High-Significance Measurement of Correlation Between Unresolved IRAS Sources and Optically-Selected Galaxy Clusters
Creators: name: Hincks, Adam D.
name: Hajian, Amir
name: Addison, Graeme E.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We cross-correlate the 100 um Improved Reprocessing of the IRAS Survey (IRIS) map and galaxy clusters at 0.1 < z < 0.3 in the maxBCG catalogue taken from the Sloan Digital Sky Survey, measuring an angular cross-power spectrum over multipole moments 150 < l < 3000 at a total significance of over 40 sigma. The cross-spectrum, which arises from the spatial correlation between unresolved dusty galaxies that make up the cosmic infrared background (CIB) in the IRIS map and the galaxy clusters, is well-fit by a single power law with an index of -1.28 +/- 0.12, similar to the clustering of unresolved galaxies from cross-correlating far-infrared and submillimetre maps at longer wavelengths. Using a recent, phenomenological model for the spectral and clustering properties of the IRIS galaxies, we constrain the large-scale bias of the maxBCG clusters to be 2.6 +/- 1.4, consistent with existing analyses of the real-space cluster correlation function. The success of our method suggests that future CIB-optical cross-correlations using Planck and Herschel data will significantly improve our understanding of the clustering and redshift distribution of the faint CIB sources.
description: 14 pages, 4 figures
title: A New Resourcefulness
Creators: name: Clay, Christa
Publisher: name: Emily Carr University of Art and Design
Year: 2022
Subjects: subject: Circular economy
valueUri: https://id.loc.gov/authorities/subjects/sh2021015542
subject: Sustainability
valueUri: https://id.loc.gov/authorities/subjects/sh2009000375
subject: Sustainable design
valueUri: https://id.loc.gov/authorities/subjects/sh2007001468
subject: Design
valueUri: https://id.loc.gov/authorities/subjects/sh85037197

description: This thesis reflects on our relationships to the materials and objects that we are surrounded with, the agency they carry, as well as the responsibility we have to the places and communities we inhabit. This context makes way for a narrative on localization, circularity, and resiliency. A New Resourcefulness offers auto-ethnography woven throughout theory and design practice, as experienced in British Columbia, Canada. Includes the essay: Ecological Restoration through Material Practice: Invasive Species as Resource, by Christa Clay and Chiara Schmitt (pp. 88 - 98).
Rubus ulmifolius Schott
Creators: name: Becherer
Publisher: name: Zenodo
Year: 1956
Subjects: Biodiversity
Taxonomy

description: R. ulmifolius Schott Bis 1380m: ob Fully (Garns). l: Vernayaz-Salvan(J.); Finhaut(Schmidely).- 3a:Gondoschlucht zwischender Casermetta und Gondo (Becherer). Var.subtruncatus (Sudre) R. Keller - l: Bei Gueuroz (Coquoz);Les Marecottes (idem). Var.dilatatifolius (Sudre) Schmidely - l: Les Marecottes (Coquoz); Leizettes (idem). Var.msignitus (Timbal-Lagraveet Ph.J. Müller) R. Keller - l: St-Maurice (herb. Lausanne). Subvar.rusticus Schmidely - l: Les Marecottes(Coquoz). Subvar.contractifolius (Sudre) Schmidely - l: Ob Monthey (Corboz). - 2: An der Sarvaz bei Saillon (Garns). 1 Die vom Verfasser auf der Simplonsüdseite gesammelten Rubus-Formen sind von E. OBERHOLZER bestimmt worden. Var. anisodon (Sudre) Schmidely - l: Les Marecottes (Coquoz). Var.vulgatus Schmidely - l: St-Maurice (Favrat). Var. heteromorphus (Ripart) R. Keller - 2: Champlan (Favrat). Subvar. Lemaitrei (Ripart) Sudre - «Wallis» (Favrat).- l:Mont d'Ottan(F.).
description: Published as part of Becherer, 1956, Florae Vallesiacae Supplementum, pp. 1-556 in Denkschriften der Schweizerischen Naturforschenden Gesellschaft 71 on pages 1-556
Social Security; Abortion; Pam Elam; Joyce Miller, Solidarity Day
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2020
Subjects: Social security
Abortion--Law and legislation
Helplines

description: Side A: Bella Abzug on abortion; P. Segal on Social security; Pam Elam on July 4th. Side B: Joyce Miller, solidarity day
Balta Tepper 1893
Creators: name: Che, Yanli
name: Chen, Li
name: Wang, Zongqing
Publisher: name: Zenodo
Year: 2010
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Ectobiidae
Balta

description: Balta Tepper, 1893
 Mareta Bolívar, 1895: 371.
 Supellina Chopard, 1921: 760. Allactina Hebard, 1929: 18.
 Hebardula Uvarov, 1939: 457.
 Type species: Balta epilamproides Tepper, 1893:39
Vertex with interocular space slightly less than or about the same as distance between antennal sockets. Pronotum subelliptical and flattened, concealing head and mesonotum, with anterior margin nearly truncate and middle of posterior margin slightly convex. Tegmina and hind wings usually fully developed and reaching well beyond end of abdomen, hind wings shorter than tegmina. Tegmen with longitudinal or sublongitudinal discoidal sectors. Hind wing with costal veins clubbed or thickened distally, or not; medial vein straight and usually simple, rarely with branches; cubital vein with complete branches, incomplete branches generally absent, apical triangle present but small. Front femur of Type C2 (anteroventral margin stout proximal spines absent, a row of piliform spinules present, terminating in 2 stout spines), rarely of Type B3 (anteroventral margin of front femur with 3 proximal spines followed by a row of piliform spinules, terminating in 3 large apical spines) or another type; pulvilli present on 4 proximal tarsomeres, tarsal claws strongly asymmetrical and unspecialized, arolia present. Male: abdominal terga unspecialized. Supraanal plate transverse, middle of apical margin slightly concave or convex, symmetrical, right and left paraprocts similar or asymmetrical, without spinelike processes. Subgenital plate symmetrical or slightly asymmetrical, apical margin with Vshaped incision in middle, styli widely separated, each in a posterolateral corner of plate. Genital hook on right side.
 Distribution. Oriental, Australian, African and Palaearctic Region.
description: Published as part of Che, Yanli, Chen, Li & Wang, Zongqing, 2010, Six new species of the genus Balta Tepper (Blattaria, Pseudophyllodrominae) from China, pp. 55-67 in Zootaxa 2609 on pages 55-56, DOI: 10.5281/zenodo.197769
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Creators: name: Li, Yun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped on the Immunochip, including 10,588 cases and 22,806 controls. We identified 15 new susceptibility loci, increasing to 36 the number associated with psoriasis in European individuals. We also identified, using conditional analyses, five independent signals within previously known loci. The newly identified loci shared with other autoimmune diseases include candidate genes with roles in regulating T-cell function (such as RUNX3, TAGAP and STAT3). Notably, they included candidate genes whose products are involved in innate host defense, including interferon-mediated antiviral responses (DDX58), macrophage activation (ZC3H12C) and nuclear factor (NF)-κB signaling (CARD14 and CARM1). These results portend a better understanding of shared and distinctive genetic determinants of immune-mediated inflammatory disorders and emphasize the importance of the skin in innate and acquired host defense.
On the asymptotics of the principal eigenvalue for a Robin problem with a large parameter in planar domains
Creators: name: Pankrashkin, Konstantin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Spectral Theory (math.SP)
subject: FOS: Mathematics

description: Let $Ω\subset \RR^2$ be a domain having a compact boundary $Σ$ which is Lipschitz and piecewise $C^4$ smooth, and let $ν$ denote the inward unit normal vector on $Σ$. We study the principal eigenvalue $E(β)$ of the Laplacian in $Ω$ with the Robin boundary conditions $\partial f/\partialν+βf=0$ on $Σ$, where $β$ is a positive number. Assuming that $Σ$ has no convex corners we show the estimate $E(β)=-β^2- γ_\mxβ+ O\big(β^\{2}{3}\big)$ as $β\to+\infty$, where $γ_\mx$ is the maximal curvature of the boundary.
description: 12 pages, contribution to the proceedings of the conference "Mathematical Challenge of Quantum Transport in Nanosystems" (Pierre Duclos Workshop), Saint-Petersburg, Russia, March 13-15, 2013
Dynamical and collisional constraints on a stochastic late veneer on the terrestrial planets
Creators: name: Raymond, Sean N.
name: Schlichting, Hilke E.
name: Hersant, Franck
name: Selsis, Franck
Publisher: name: arXiv
Year: 2013
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Given their tendency to be incorporated into the core during differentiation, the highly-siderophile elements (HSEs) in Earth's mantle are thought to have been accreted as a `late veneer' after the end of the giant impact phase. Bottke et al (2010) proposed that the large Earth-to-Moon HSE abundance ratio can be explained if the late veneer was characterized by large (D = 1000-4000km) impactors. Here we simulate the evolution of the terrestrial planets during a stochastic late veneer phase from the end of accretion until the start of the late heavy bombardment ~500 Myr later. We show that a late veneer population of 0.05 Earth masses dominated by large (D > 1000km) bodies naturally delivers a ~0.01 Earth mass veneer to Earth, consistent with constraints. The eccentricities and inclinations of the terrestrial planets are excited by close encounters with the largest late veneer bodies. We find the best agreement with their post-veneer orbits if either a) the terrestrial planets' pre-veneer angular momentum deficit AMD_0 was less than half of the current one AMD_now, or b) AMD_0 <= AMD_now and the veneer was limited to smaller (D_max <= 2000km) bodies. Veneer impacts on Venus, Earth and Mars were mostly accretionary but on Mercury and the Moon they were mostly erosive. In ~20% of simulations an energetic impact occurred that could have removed >25% of Mercury's mass, thereby increasing its iron mass fraction. We show that, due to the erosive nature of larger impacts, the Moon cannot accrete any material from objects larger than 500-1000km. The large Earth-to-Moon HSE abundance ratio is explained if the late veneer included large impactors (D >= 500-1000km) regardless of their size distribution, as long as most of Earth's veneer came from large bodies. The spin angular momenta imparted by stochastic late veneer impacts was far in excess of the current ones for Mercury and Venus.
description: Icarus, in press. 33 pages, 5 figures
Walking the Line: Serbia, Democracy, European Union Membership, and an Independent Kosovo
Creators: name: Scekic, Sofia
Publisher: name: Stanford Digital Repository
Year: 2023
Subjects: subject: Serbia
subject: Kosovo
subject: Democracy
subject: European Union
subject: Conflict
subject: Vucic
subject: Democratic reforms
subject: Negotiations
subject: EU accession
subject: Rule of law
subject: Democratic backsliding
subject: China
subject: Stanford University
subject: Humanities and Sciences
subject: Public Policy Program

description: In 2000, Serbia experienced a democratic breakthrough as part of the global ‘third wave of democratization.’ During the following democratic consolidation process, Serbian political leaders indicated their desire to strengthen the country’s relationship with the European Union, and Serbia became an EU candidate country in 2012. To become an EU member country, Serbia is required to meet conditions such as democratic reforms and a resolution to its conflict with Kosovo. However, under current President Aleksandar Vucic, the country has moved closer to authoritarianism without making tangible progress on normalizing relations with Kosovo. This thesis attempts to answer the following question: does Vucic have any incentive to resolve the Kosovo issue, given EU membership is conditional on democratic reforms in addition to normalization of relations with Kosovo?
20240612 DOWLOAD BIOTIN JCTECR-S-24-00024 (1).pdf
Creators: name: Shankar, Srushti
name: Srikanta, Sathyanarayana
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320208
subject: Endocrinology

description: 20240612 DOWNLOAD BIOTIN JCTECR-S-24-00024
Weiterentwicklung von Bemessungsverfahren in planfreien Knotenpunkten
Creators: name: Dammann, Wiebke
Publisher: name: Hannover : Universität
Year: 2004
Subjects: subject: Grade separated junction
subject: quality of traffic flow
subject: capacity
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: [no abstract]
Checking the Cox model with cumulative sums of martingale-based residuals
Creators: name: Ying, Z.
name: Lin, Danyu
name: Wei, L.J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: This paper presents a new class of graphical and numerical methods for checking the adequacy of the Cox regression model. The procedures are derived from cumulative sums of martingale-based residuals over follow-up time and/or covariate values. The distributions of these stochastic processes under the assumed model can be approximated by zero-mean Gaussian processes. Each observed process can then be compared, both visually and analytically, with a number of simulated realizations from the approximate null distribution. These comparisons enable the data analyst to assess objectively how unusual the observed residual patterns are. Special attention is given to checking the functional form of a covariate, the form of the link function, and the validity of the proportional hazards assumption. An omnibus test, consistent against any model misspecification, is also studied. The proposed techniques are illustrated with two real data sets.
Masses of galaxy clusters from gravitational lensing
Creators: name: Hoekstra, Henk
name: Bartelmann, Matthias
name: Dahle, Haakon
name: Israel, Holger
name: Limousin, Marceau
name: Meneghetti, Massimo
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Despite consistent progress in numerical simulations, the observable properties of galaxy clusters are difficult to predict ab initio. It is therefore important to compare both theoretical and observational results to a direct measure of the cluster mass. This can be done by measuring the gravitational lensing effects caused by the bending of light by the cluster mass distribution. In this review we discuss how this phenomenon can be used to determine cluster masses and study the mass distribution itself. As sample sizes increase, the accuracy of the weak lensing mass estimates needs to improve accordingly. We discuss the main practical aspects of these measurements. We review a number of applications and highlight some recent results.
description: Review paper (48 pages, 15 figures). Accepted for publication in Space Science Reviews (eds: S. Ettori, M. Meneghetti). This is a product of the work done by an international team at the International Space Science Institute (ISSI) in Bern on "Astrophysics and Cosmology with Galaxy Clusters: the X-ray and Lensing View"
Die numerische Kompetenz von Vorschulkindern : theoretische Modelle und empirische Befunde
Creators: name: Caluori, Franco
Publisher: name: Hannover : Universität
Year: 2004
Subjects: subject: Competence of counting
subject: OTZ
subject: nursery-school
subject: Dewey Decimal Classification::100 | Philosophie::150 | Psychologie
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::370 | Erziehung, Schul- und Bildungswesen

description: [no abstract]
Wasserbildern auf der Spur : systematische Untersuchungen an Wasserschleiern und an Wassertreppen
Creators: name: Seegert, Anke
Publisher: name: Hannover : Universität
Year: 2004
Subjects: subject: Waterfeaturea
subject: waterveil
subject: watersteps
subject: Dewey Decimal Classification::700 | Künste, Bildende Kunst allgemein::710 | Landschaftsgestaltung, Raumplanung

description: [no abstract]
Deep learning for the detection of machining vibration chatter
Creators: name: Kounta, Cheick Abdoul Kadir A.
name: Arnaud, Lionel
name: Kamsu-Foguem, Bernard
name: Tangara, Fana
Publisher: name: arXiv
Year: 2023
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Most of the work on chatter detection is based on laboratory machining tests, thus without the constraints of noise, the variety of situations to be managed in the industry, and the uncertainties on the parameters (sensor position, tool engagement, and sometimes even spindle rotation frequency). This work presents an approach first based on mechanical skills first to identify the optimal signal processing, then based on deep learning to automatically detect the phenomenon of chatter in machining. To do so, we use input images from the Fast Fourier Transform analysis of a vibration signal from the machining of an Alstom industrial railway system. The FFT images are first cropped in height to perform a renormalization of the signal scale. This renormalization step eliminates a bias regularly observed in the literature, which did not eliminate a simple correlation with signal amplitude because chatter is often, but not always, associated with stronger vibrations. Deep learning extracted features from the image data by exploiting pre-trained deep neural networks such as VGG16 and ResNet50. The data is derived from an industrial vibration signal (with noise, a not ideally placed sensors, and uncertainties on process parameters), which was very poorly represented in the literature. It is shown that by depleting the signal (renormalized amplitude and absence of information on the rotation speed), the model obtains a good result (an accuracy of 99% in the training and validation phases), which had never been done in the literature. In addition, since a part of the test dataset is similar to the training dataset, the proposed model obtains an accuracy of 98.82%. The robustness is proved by adding another test dataset containing noisy and more or less ambiguous images to be classified. The model still manages to detect these cases from its training of unambiguous cases, showing that the obtained generalization is efficient with an accuracy of 73.71%.
Decoding the message from meteoritic stardust silicon carbide grains
Creators: name: Lewis, Karen M.
name: Lugaro, Maria
name: Gibson, Brad K.
name: Pilkington, Kate
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Micron-sized stardust grains that originated in ancient stars are recovered from meteorites and analysed using high-resolution mass spectrometry. The most widely studied type of stardust is silicon carbide (SiC). Thousands of these grains have been analysed with high precision for their Si isotopic composition. Here we show that the distribution of the Si isotopic composition of the vast majority of stardust SiC grains carry the imprints of a spread in the age-metallicity distribution of their parent stars and of a power-law increase of the relative formation efficiency of SiC dust with the metallicity. This result offers a solution for the long-standing problem of silicon in stardust SiC grains, confirms the necessity of coupling chemistry and dynamics in simulations of the chemical evolution of our Galaxy, and constrains the modelling of dust condensation in stellar winds as function of the metallicity.
description: Accepted for publication on The Astrophysical Journal Letters
Student Scholarly Works in the Institutional Repository
Creators: name: Richardson, Lee M.
name: Renner, Barbara Rochen
name: Kati, Rebekah
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: This presentation reports on the process to solicit, describe and deposit health sciences students’ research posters and capstone papers into the institutional repository. We will share the various approaches used to ask for and receive content and obtain permissions to deposit. The presentation will report successes as well as challenges such as attending student research day events to have students sign deposit agreements and flexibility when working within established class workflows. This project, the first of its kind on campus, provides leadership and a framework for others to preserve student research. We will also show online exhibit space librarians created for a visual presentation of some content.