cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the thin-shell limit of branes in the presence of Gauss-Bonnet interactions
Creators: name: Barcelo, Carlos
name: Germani, Cristiano
name: Sopuerta, Carlos F.
Publisher: name: arXiv
Year: 2003
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we study thick-shell braneworld models in the presence of a Gauss-Bonnet term. We discuss the peculiarities of the attainment of the thin-shell limit in this case and compare them with the same situation in Einstein gravity. We describe the two simplest families of thick-brane models (parametrized by the shell thickness) one can think of. In the thin-shell limit, one family is characterized by the constancy of its internal density profile (a simple structure for the matter sector) and the other by the constancy of its internal curvature scalar (a simple structure for the geometric sector). We find that these two families are actually equivalent in Einstein gravity and that the presence of the Gauss-Bonnet term breaks this equivalence. In the second case, a shell will always keep some non-trivial internal structure, either on the matter or on the geometric sectors, even in the thin-shell limit.
description: 17 pages, 2 figures, RevTeX 4. Revised version accepted for publication in Physical Review D
Multiple myeloma in  a young adult. A case report
Creators: name: Emanuel Zumaya Gomez M.D.
name: Ruth Gutierrez Serdan M.D.
name: Guillermo Diaz Vargas M.D.
name: Veronica Bravo Villa M.D.
name: Judith Argelia Alducin Robles M.D.
name: Eduardo Gomez Plata M.D.
Publisher: name: Zenodo
Year: 2024

description: Background:

Introduction: Multiple myeloma (MM) is an incurable, biologically heterogeneous disease of plasma cells. It is characterized by clonal proliferation of malignant plasma cells, predominantly affecting the bone marrow microenvironment and skeletal system. MM is considered a disease of the elderly, as most cases are diagnosed at a median age of 69 years. Less than 2% of patients diagnosed with MM are younger than 40 years of age. Case report: A 32-year-old male patient with a family history of multiple myeloma, with wasting syndrome of 7 months of evolution and who presented pathological fracture of the L2 vertebra; chest Computed Tomography (CT) scan showed multiple osteolytic lesions in spinal column, and the laboratory findings showed anemia, renal insufficiency, hyperphosphatemia and hypercalcemia and the serum protein electrophoresis positive for hypergammaglobulinemia, suspecting hematological neoplasia; the histopathological study confirmed a multiple myeloma. Conclusion: In Mexico, the statistics of this type of disease have been deficient, however, this diagnosis must be considered even at young age, since timely treatment reduces morbidity and mortality of these patients, favoring their prognosis.

 

Keywords: Multiple Myeloma, Bone Disease, Cytogenetics, Oncology, Young Adults
Closed String Tachyon Condensation at c=1
Creators: name: Karczmarek, Joanna L.
name: Strominger, Andrew
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The c=1 matrix model, with or without a type 0 hat, has an exact quantum solution corresponding to closed string tachyon condensation along a null surface. The condensation occurs, and spacetime dissolves, at a finite retarded time on I^+. The outgoing quantum state of tachyon fluctuations in this time-dependent background is computed using both the collective field and exact fermion pictures. Perturbative particle production induced by the moving tachyon wall is shown to be similar to that induced by a soft moving mirror. Hence, despite the fact that I^+ for the tachyon is geodesicaly incomplete, quantum correlations in the incoming state are unitarily transmitted to the outgoing state in perturbation theory. It is also shown that, non-perturbatively, information can leak across the tachyon wall, and tachyon scattering is not unitary. Exact unitarity remains intact only in the free fermion picture.
description: Minor corrections; References added; 24 pages, 2 figures, harvmac
FC sets and twisters: the basics of orbifold deconstruction
Creators: name: Bantay, P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Algebra (math.QA)
subject: High Energy Physics - Theory (hep-th)
subject: Group Theory (math.GR)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We present a detailed account of the properties of twisters and their generalizations, FC sets, which are essential ingredients of the orbifold deconstruction procedure aimed at recognizing whether a given conformal model may be obtained as an orbifold of another one, and if so, to identify the twist group and the original model. The close analogy with the character theory of finite groups is discussed, and its origin explained.
description: 26 pages
RIVEAL Factsheet #3 - Field sampling
Creators: name: Rivaes, R
name: Aguiar, FC
Publisher: name: Zenodo
Year: 2020
Subjects: Ecosystem services
Project coordination
Project deliverable
Freshwater biodiversity
Regulated rivers

description: Third factsheet of the RIVEAL project. Presents the adopted field sampling methodology and reports the activities acomplished towards data collection, during June and July 2019, to support data analysis.
Crop Insurance and Food Security: Evidence from Rice Farmers in Eastern India
Creators: name: Ranganathan, Thiagu
name: Mishra, Ashok K.
name: Kumar, Anjani
name: Ranganathan, Thiagu
name: Mishra, Ashok K.
name: Kumar, Anjani
Publisher: name: Unknown
Year: 2018
Subjects: subject: Crop Production/Industries
subject: Risk and Uncertainty
subject: crop insurance
subject: rice yield
subject: farm size
subject: India
subject: food security
subject: treatment effects
subject: heterogeneous treatment effects

description: The paper explores the spread of crop insurance (CI) in India and analyzes the association of factors affecting the demand for crop insurance. Additionally, using large farm-level survey data from Eastern India, the study assesses CI’s impact on rice yields of smallholder rice producers. The study tests for robustness of the findings after controlling for other covariates and endogeneity. Results indicate CI has a positive and significant impact on rice yields. In particular, the ATET and ATEUT effect of CI on rice yields is about 47%. However, CI’s impact on rice yields is heterogeneous among farm sizes of smallholders. Participation in CI increased rice yields of large farms by 49% but increased rice yields of small farms by only 16%.
MEI encoding: Rondo a Capriccio in G major, Op. 129 by Ludwig van Beethoven
Creators: name: Goebl, Werner
Publisher: name: Zenodo
Year: 2021

description: Rondo a Capriccio in G major, Op. 129 by Ludwig van Beethoven, encoding of Breitkopf und Härtel edition, 1862–90. Series 18 Plate B.191.
Subject Access through Community Partnerships: A Case Study
Creators: name: Kreitz, Patricia A.
name: Brooks, Travis C.
Publisher: name: arXiv
Year: 2003
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Innovations in scholarly communication have resulted in changing roles for authors, publishers and libraries. Traditional roles are disappearing and players are actively seeking or reluctantly assuming new roles. Library roles are changing as they become involved in building and indexing electronic (e-) repositories and support new modes of e-research. A library-run service, the SPIRES particle physics databases, has not only weathered, but also lead, many of the transitions that have shaped the landscape of epublishing and e-research. This has been possible through an intense and in-depth partnership with its user community. The strategies used and lessons learned can help other libraries craft cost-effective roles in this new environment.
description: 17 Pages, Invited paper to be published in Science & Technology Libraries
Additional file 2 of The adaptation and evaluation of a CBT-based manual for the inpatient treatment of youth depression: a pilot study
Creators: name: Frey, Michael
name: Pietsch, Kathrin
name: Weninger, Laura
name: Brockhaus, Matthias
name: Loy, Fabian
name: Claus, Nathalie
name: Wagenbüchler, Petra
name: Kornbichler, Selina
name: Kroboth, Jana
name: Georgii, Beatrice
name: Wermuth, Inga
name: Kititsina, Anna
name: Heiser, Katharina
name: Schulte-Körne, Gerd
name: Platt, Belinda
Publisher: name: figshare
Year: 2020
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2. The interview schedule for the focus group
The performance of the single-walled carbon nanotube covalently modified with polyethylene glycol to delivery of Gemcitabine anticancer drug in the aqueous environment
Creators: name: Heidar Moradnia
name: Heidar Raissi
name: Shahabi, Mahnaz
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Computational Biology

description: A computational investigation of Gemcitabine drug adsorption on the single-walled carbon nanotube covalently modified with polyethylene glycol in a series of the configurations is studied using density functional theory calculations. It is observed that O…H hydrogen bonds are the dominating intermolecular interactions during the complex formation between anti-cancer drug and the nanotube. The studied hydrogen-bonded complexes are treated theoretically to elucidate the nature of the intermolecular hydrogen bonds, geometrical structures, the binding energy and electron density topological analysis. The existence of the bond critical points between hydrogen and the electronegative atoms and their concomitant bond paths which connect the bond critical points to the two interacting atoms confirm by Quantum Theory of Atoms in Molecules method. In addition, considering the charge transfer for all of the adsorbed configurations reveals the capability of the drug molecule to accept precisely the electron from the functionalized carbon nanotube during the drug adsorption on external surface of the carbon nanotube. Also, the effect of weight percent of polyethylene glycol on the drug adsorption strength is investigated by molecular dynamics simulations. Communicated by Ramaswamy H. Sarma
U.S. Rice Production in the New Millennium: Changes in Structure, Practices, and Costs
Creators: name: McBride, William D.
name: Skorbiansky, Sharon Raszap
name: Childs, Nathan
name: McBride, William D.
name: Skorbiansky, Sharon Raszap
name: Childs, Nathan
Publisher: name: Unknown
Year: 2018
Subjects: subject: Agricultural and Food Policy
subject: Agricultural Finance
subject: rice
subject: farm productivity
subject: hybrid seed
subject: precision farming
subject: cost-of-production
subject: economies of size
subject: Agricultural Resource Management Survey

description: Farms growing rice changed significantly over the past two decades in terms of operation size and the ways in which rice is produced. As the total number of farms growing rice declined (from 9,627 in 1997 to 5,591 in 2012), total U.S. planted rice acres also dropped at an annual average rate of about 0.75 percent between 1995 and 2017. U.S. farms growing rice expanded that acreage more than 50 percent between 2000 and 2013 to an average of 600 acres per farm. Farm size increased most in the South where larger farms were able to take advantage of size economies. The most significant change in rice production technologies from 2000 to 2013 was the introduction and adoption of new rice seed varieties. Southern rice producers increasingly planted hybrid and non-genetically modified herbicide-tolerant seed. Precision farming technologies also proliferated, especially the use of yield monitors and guidance systems for tractors and other self-propelled machines. The adoption of new technologies in rice farming pushed per-acre production costs higher, but rice yields also increased, offsetting much of the higher costs. U.S. rice production saw an estimated productivity gain of 29 percent from 2000 to 2013, about 2.2 percent annually. Structural and productivity changes on U.S. farms growing rice benefited U.S. domestic rice consumers by helping to keep prices low and enhanced the competitiveness of U.S. rice producers in global markets.
Mass ejection from disks surrounding a low-mass black hole: Viscous neutrino-radiation hydrodynamics simulation in full general relativity
Creators: name: Fujibayashi, Sho
name: Shibata, Masaru
name: Wanajo, Shinya
name: Kiuchi, Kenta
name: Kyutoku, Koutarou
name: Sekiguchi, Yuichiro
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: New viscous neutrino-radiation hydrodynamics simulations are performed for accretion disks surrounding a spinning black hole with low mass $3M_\odot$ and dimensionless spin 0.8 or 0.6 in full general relativity, aiming at modeling the evolution of a merger remnant of massive binary neutron stars or low-mass black hole-neutron star binaries. We reconfirm the following results found by previous studies of other groups: 15-30% of the disk mass is ejected from the system with the average velocity of $\sim $5-10% of the speed of light for the plausible profile of the disk as merger remnants. In addition, we find that for the not extremely high viscous coefficient case, the neutron richness of the ejecta does not become very high, because weak interaction processes enhance the electron fraction during the viscous expansion of the disk before the onset of the mass ejection, resulting in the suppression of the lanthanide synthesis. For high-mass disks, the viscous expansion timescale is increased by a longer-term neutrino emission, and hence, the electron fraction of the ejecta becomes even higher. We also confirm that the mass distribution of the electron fraction depends strongly on the magnitude of the given viscous coefficient. This demonstrates that a first-principle magnetohydrodynamics simulation is necessary for black hole-disk systems with sufficient grid resolution and with sufficiently long timescale (longer than seconds) to clarify the nucleosynthesis and electromagnetic signals from them.
description: 26 pages, 15 figures, to be submitted to PRD
Quantum chaos viewed from quantum action
Creators: name: Huard, D.
name: Kröger, H.
name: Melkonyan, G.
name: Nadeau, L. P.
name: Moriarty, K. J. M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We consider a mixed chaotic Hamiltonian system and compare classical with quantum chaos. As alternative to the methods of enegy level spacing statistics and trace formulas, we construct a quantum action and a quantum analogue phase space to analyse quantum chaos.
description: talk by Helmut Kr\"oger at Conf. on Found. of Quant. Mech., Vaxjo (Sweden) 2003
Observational evidence for supermassive black hole binaries
Creators: name: Komossa, Stefanie
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Coalescing massive black hole binaries are powerful emitters of gravitational waves, in the LISA sensitivity range for masses M_BH ~ 10^{4-7} M_sun. According to hierarchical galaxy merger models, binary black holes should form frequently, and should be common in the cores of galaxies. The presence of massive black hole binaries has been invoked to explain a number of class properties of different types of galaxies, and in triggering various forms of activity. The search for such binary black holes is therefore of great interest for key topics in astrophysics ranging from galaxy formation to activity in galaxies. A number of phenomena were attributed to the presence of supermassive binary black holes, including X-shaped radio galaxies and double-double radio galaxies, helical radio-jets, periodicities in the lightcurves of blazars, (double-horned emission-line profiles), binary galaxies with radio-jet cores, binary quasars, and the X-ray active binary black hole at the center of the galaxy NGC 6240. Here, I review the observational evidence for the presence of supermassive binary black holes in galaxies, and the scenarios which have been discussed to explain these observations.
description: 14 pages, to appear in "The Astrophysics of Gravitational Wave Sources" (Maryland, April 2003), AIP in press, J. Centrella (ed); preprint with figures in full resolution and related papers are available at http://www.xray.mpe.mpg.de/~skomossa/
Providing a vehicle of support on the road to energy independence for the seven generations of the Skeetchestn First Nation
Creators: name: Haley, Brigit O. E.
Publisher: name: The University of British Columbia
Year: 2016

description: The Skeetchestn First Nation has resided in their traditional, unceded territory since time immemorial. Despite pressures to assimilate, the on-reserve community has experienced a recent resurgence. The intention of this paper was to initiate the community energy planning process and to compare the energy consumption of a conventional on-reserve house to the traditional style Round House. An Energy Awareness questionnaire was circulated through the community to determine the importance of energy related issues; highlighting energy independence, residential energy use and climate change. The questionnaire results were used to facilitate an open-dialogue to draft the energy objectives during the community energy planning breakfast. Both events were well received with 35% response rate and 31% participation rate, respectively. Two home energy audits were performed to satisfy the HOT2000 analysis in comparing the energy consumption of the two houses. Base case and upgrade models were simulated; the former indicated the conventional on-reserve house consumed 83% more energy than the traditional style Round House. The latter indicated the conventional on-reserve house consumed 59% more energy than the Round House. Overall, the findings support the salience of the housing crisis in First Nation communities and validate the dire need for affordable, safe and culturally appropriate housing. More specifically the findings indicate that the Round House should be considered as the primary option for future residential development.
America’s Diverse Family Farms, 2018 Edition
Creators: name: Burns, Christopher B.
name: MacDonald, James M.
name: Burns, Christopher B.
name: MacDonald, James M.
Publisher: name: Unknown
Year: 2018
Subjects: Research Methods/ Statistical Methods

description: The farm typology, or classification, developed by ERS primarily focuses on the “family farm,” or any farm where the majority of the business is owned by an operator and individuals related to the operator. USDA defines a farm as any place that produced and sold—or normally would have produced and sold—at least $1,000 of agricultural products during a given year. USDA uses acres of crops and head of livestock to determine if a place with sales of less than $1,000 could normally produce and sell that amount. Farm size is measured by gross cash farm income (GCFI), a measure of the farm’s revenue that includes sales of crops and livestock, Government payments, and other farm-related income, including fees from production contracts.
In Silico Identification and Evaluation of Bacillus subtilis Cold Shock Protein B (cspB)-like Plant RNA Chaperones
Creators: name: , Suman
name: Chaudhary, Meenakshi
name: Vikrant Nain
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology
subject: 60506 Virology

description: Cold shock domain (CSD) proteins with nucleic acid binding properties are well conserved from bacteria to higher organisms. In bacteria, the cold shock proteins (CSPs) are single domain RNA chaperones, whereas in animals and plants, CSDs are accompanied by additional domains with roles in transcription regulation. Bacterial CSPs (Escherischia coli-cspA and Bacilus subtilis-cspB) have successfully imparted drought tolerance in transgenic plants; however, these cannot be deployed in food crops due to their low public acceptance of transgenics with bacterial genes. Therefore, this study aimed to identify CSPB-like proteins from plants that can be used for developing drought tolerant transgenic crops. Twelve single domain plant CSPs presenting >40% sequence identity with CSPB were identified. All 12 plant CSPs were modeled by homology modeling and refined by molecular dynamics simulation for 10 ns. Selected plant CSPs and CSPB exhibited high structural similarity (Tm-score: 0.63–0.86). Structure based phylogenetic analysis revealed that Triticum aestivum-csp1 and Aegilops tauschii-cspE are structurally closer to CSPB compared to their orthologs and paralogs. Molecular docking with three RNA molecules (5U, UC3U, and C2UC) indicates that Ricinus communis-csd1 and T. aestivum-csp1 have a binding pattern and docking scores similar to those of CSPB. Furthermore, MD simulations for 20 ns and analysis of RMSD, RMSF, Rg, as well as the number of hydrogen bonds in all the three complexes revealed that plant CSP-RNA complexes behave in a similar manner to that of the CSPB-RNA complex, making them highly potential candidate genes for developing drought tolerance in transgenic plants.
Volkov-Pankratov states in topological graphene nanoribbons
Creators: name: Berg, Tineke L. van den
name: De Martino, Alessandro
name: Calvo, M. Reyes
name: Bercioux, Dario
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: In topological systems, a modulation in the gap onset near interfaces can lead to the appearance of massive edge states, as were first described by Volkov and Pankratov. In this work, we study graphene nanoribbons in the presence of intrinsic spin-orbit coupling smoothly modulated near the system edges. We show that this space modulation leads to the appearance of Volkov-Pankratov states, in addition to the topologically protected ones. We obtain this result by means of two complementary methods, one based on the effective low-energy Dirac equation description and the other on a fully numerical tight-binding approach, finding excellent agreement between the two. We then show how transport measurements might reveal the presence of Volkov-Pankratov states, and discuss possible graphene-like structures in which such states might be observed.
description: 12 pages, 8 figures
title: The Role of RecX in Mycobacteria
Creators: name: Manglani, Sapna Lakhi
Publisher: name: The Open University
Year: 2010

description: Tuberculosis is a major global public health problem which causes millions of deaths every year. It is caused by the bacterium Mycobacterium tuberculosis, which survives and replicates within host macrophages, in which it has to overcome the effects of various DNA damaging agents in order to survive.

 In bacteria, the RecA protein regulates DNA-damage repair. RecA also plays a central role in regulation of the SOS response and homologous recombination. In Mycobacterium smegmatis and Mycobacterium tuberculosis, downstream of, overlapping and co-transcribed with recA is the recX gene. Using a recA-recX deletion mutant of M. smegmatis, it has been shown that the over expression of recA is toxic in the absence of recX, suggesting that RecX plays a regulatory role on RecA.

 This project is aimed at investigating the hypothesis that RecX plays a regulatory role in RecA function in Mycobacterium tuberculosis. Various in vivo and in vitro studies were carried out to test this hypothesis and characterise the nature of RecA regulation by RecX.

 To investigate their mode of interaction, the purified RecX protein was used in DNA mobility shift assays to look for interactions with the M. smegmatis and M. tuberculosis recA upstream regions. No interaction was observed, suggesting that RecX does not regulate recA expression at the transcriptional level. A positive interaction was found for RecA and RecX in a yeast two-hybrid study, demonstrating a post-translational mode of interaction and regulation.

 The in vitro studies included LexA cleavage and ATP hydrolysis studies. When activated RecA is incubated with LexA, it results in the RecA-mediated auto catalytic cleavage of LexA. When RecX was added with RecA, a clear inhibition in LexA cleavage was observed. All reactions promoted by RecA in vitro are dependent on its binding to single-stranded DNA in the presence of ATP to produce an active nucleoprotein filament. It was found in ATPase assays, that RecX inhibits RecA ATP hydrolysis activity.

 To investigate the function of RecX in vivo, an assay was carried out to determine whether recX promotes survival when expression of recA is induced by DNA damage. A recA-recX deletion mutant of M smegmatis complemented with M. smegmatis recA+recX showed a higher percentage survival following DNA damage than when complemented with recA alone. Using the same recA-recX deletion strain of M. smegmatis in a homologous recombination assay, it was found that there is an increase in the frequency of double crossover events in recA+recX strains when compared to ΔrecX strains. Further in vivo studies demonstrated that recX enhances the recovery of RecA levels following pulse DNA damage.
Assessment of the hypoglycemic effect of Bixin in alloxan-induced diabetic rats: in vivo and in silico studies
Creators: name: Keita, Hady
name: Cleydson Breno Rodrigues Dos Santos
name: Matheus Mercês Ramos
name: Padilha, Elias Carvalho
name: Serafim, Rodolfo Bortolozo
name: Castro, Andres Navarrete
name: Amado, Jesus Rafael Rodriguez
name: Da Silva, Gabriel Monteiro
name: Irlon Maciel Ferreira
name: Giuliatti, Silvana
name: Carvalho, José Carlos Tavares
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: The objectives of this study were to extract and purify Bixin from the seeds of Bixa orellana and to evaluate its hypoglycemic activity in vivo, as well as, to conduct an in silico study of selectivity on peroxisome proliferator-activated receptors via molecular docking and molecular dynamics simulations. Oral administration of Bixin (10 mg/kg) significantly reduced their glucose level that was alloxan-induced diabetic rats. Bixin showed in silico selectivity on peroxisome proliferator-activated receptors (PPARs), particularly by the peroxisome proliferator-activated receptor gamma (PPARγ), which supports the hypoglycemic activity of Bixin. From the results obtained, it can be inferred that Bixin presents hypoglycemic characteristics, which was confirmed by the results obtained from the in vivo and in silico tests. Bixin may act by other pathways to control blood glucose and thus it is possible that it presents a different toxicity profile than troglitazone, rosiglitazone and pioglitazone. However, more studies on the activity and toxicity of Bixin are needed to evaluate for further clinical use. Communicated by Ramaswamy H. Sarma
Temperature-Dependent Resistivity of Alternative Metal Thin Films
Creators: name: Siniscalchi, Marco
name: Tierno, Davide
name: Moors, Kristof
name: Tokei, Zsolt
name: Adelmann, Christoph
Publisher: name: arXiv
Year: 2020
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The temperature coefficients of the resistivity (TCR) of Cu, Ru, Co, Ir, and W thin films have been investigated as a function of film thickness below 10 nm. Ru, Co, and Ir show bulk-like TCR values that are rather independent of the thickness whereas the TCR of Cu increases strongly with decreasing thickness. Thin W films show negative TCR values, which can be linked to high disorder. The results are qualitatively consistent with a temperature-dependent semiclassical thin film resistivity model that takes into account phonon, surface, and grain boundary scattering.
description: 11 pages, 4 figures
Universal dependence of the fluctuation-dissipation ratio on the transition rates in trap models
Creators: name: Ritort, F.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We investigate violations of the fluctuation-dissipation theorem in two classes of trap models by studying the influence of the perturbing field on the transition rates. We show that for perturbed rates depending upon the value of the observable at the arrival trap, a limiting value of the fluctuation-dissipation ratio does exist. However, the mechanism behind the emergence of this value is different in both classes of models. In particular, for an entropically governed dynamics (where the perturbing field shifts the relative population of traps according to the value of the observable) perturbed rates are argued to take a form that guarantees the existence of a limiting value for the effective temperature, utterly related to the exponential character of the distribution of trap energies. Fluctuation-dissipation (FD) plots reproduce some of the patterns found in a broad class of glassy systems, reinforcing the idea that structural glasses self-generate a dynamical measure that is captured by phenomenological trap models.
description: 15 pages, 4 figures (Latex) Misprints corrected and additional comments included in Section 4. Contribution to a special issue of J. Phys. A "Statistical Physics of Disordered Systems"
Molecular modeling studies of pyrrolo[2,3-d]pyrimidin-4-amine derivatives as JAK1 inhibitors based on 3D-QSAR, molecular docking, molecular dynamics (MD) and MM-PBSA calculations.
Creators: name: Seketoulie Keretsu
name: Swapnil P. Bhujbal
name: Cho, Seung Joo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Rheumatoid Arthritis (RA) is an autoimmune disease caused by overproduction of pro-inflammatory cytokines. Janus Kinases (JAKs) mediate cytokines signaling through the Janus Kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathways. Clinical studies have shown that Janus kinase 1 (JAK1) mediated signaling plays a key role in synovial response in rheumatoid arthritis. Hence, the inhibition JAK1 is considered as an important therapeutic route for treatment of rheumatoid arthritis. In this study, we have performed three-dimensional quantitative structure-activity relationship (3D-QSAR), molecular docking, molecular dynamics (MD) and free energy calculations on a series of pyrrolo[2,3-d]pyrimidin-4-amine JAK1 inhibitors. Molecular docking studies of the compounds 03, 13, 36 and 49 with JAK1 were performed to study the binding interactions. The binding conformations of the compounds from docking studies were selected based on binding energy and H-bond interactions and were used as initial structure for MD simulations. Using 3D-QSAR techniques, a ligand-based comparative molecular field analysis (CoMFA) model (q2 = 0.5, r2 = 0.96) and a receptor-based CoMFA model (q2 = 0.78, r2 = 0.98) were developed. Analysis of the MD results of the most active compound (compound 49) with JAK1 showed the formation of H-bond interactions residues Glu957, Leu959 and Gly887 and water-mediated H-bond interaction with Gly887 and His885. Based on the contour map analyses of the receptor-based CoMFA, a design strategy was proposed and was used for designing new JAK1 inhibitors. Two of the designed compounds (D57 and D58) showed predicted activity values (pIC50> 8.8) greater than the most active compound for JAK1. MM-PBSA based free energy calculations indicated that the two designed compounds were able to form stable binding with JAK1 primarily through electrostatic interactions and van der Waal interactions. Collectively, the outcome of this study can be used to further the progress of JAK1 inhibition for the treatment of rheumatoid arthritis.
Δημιουργία συνόλου δεδομένων προσομοίωσης για την εκπαίδευση και τον έλεγχο ανίχνευσης μη επανδρωμένου αεροσκάφους με τεχνικές βαθιάς μάθησης
Creators: name: Αναστασιάδης, Χαράλαμπος Δημοσθένη
Publisher: name: Aristotle University of Thessaloniki
Year: 2021
Subjects: Βαθιά μάθηση
Σύνολο δεδομένων προσομοίωσης
Μη επανδρωμένο αεροσκάφος
Deep Learning
Simulation dataset
Unmanned Aircraft Vehicle

description: Η παρούσα διπλωματική εργασία ασχολείται με την χρήση της μηχανικής όρασης για την ανίχνευση αντικειμένων με τεχνικές βαθιάς μάθησης. Η ανίχνευση αντικειμένων με την χρήση μηχανικής όρασης είναι ένας τομέας ο οποίος τα τελευταία χρόνια παρουσιάζει την έντονη ανάγκη εφαρμογής σε ολοένα και περισσότερους τομείς της καθημερινότητας. Στα πλαίσια της εργασίας, επιχειρείται η δημιουργία μιας κατάλληλης βάσης δεδομένων και η χρησιμοποίηση της για την εκπαίδευση και τον έλεγχο της ανίχνευσης μη επανδρωμένου αεροσκάφους με τεχνικές βαθιάς ενισχυτικής μάθησης. Στα εισαγωγικά κεφάλαια δίνονται πληροφορίες για τα μη επανδρωμένα αεροσκάφη και για την χρήση τους σε διαφόρους τομείς της καθημερινότητας. Ακόμη, παρουσιάζονται η πλατφόρμα δημιουργίας παιχνιδιών Unreal Engine και η χρήση του προσομοιωτή AirSim. Αναλύεται ο τρόπος κατασκευής του συνόλου δεδομένων με την χρήση φυσικών λήψεων από drone και του προσομοιωτή AirSim στο περιβάλλον της μηχανής παιχνιδιών Unreal Engine. Παρουσιάζονται τα αποτελέσματα της ανίχνευσης drone με την χρήση του ανιχνευτή YOLOv4 και τα συμπεράσματα που προέκυψαν μετά την μελέτη των δεδομένων της ανίχνευσης.
description: The present thesis deals with the use of computer vision for object detection with deep learning techniques. Object detection using computer vision is a field that has many applications in everyday life. A significant part of the work deals with the creation of a database and its use for training and testing a Convolutional Neural Network-based detector for the detection of unmanned aerial vehicles. Initially information about drones and their usage in various areas of everyday life is given. The Unreal Engine game engine and the AirSim simulator are also described. The following chapters cope with the construction of the data set using physical drone videos and the AirSim simulator in the environment of the Unreal Engine. The results and the conclusions that emerged from drone detection in this dataset using the YOLOv4 detector are presented.
Prosoeca difficile Barraclough 2005, comb. n.
Creators: name: Barraclough, David A.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Nemestrinidae
Prosoeca
Prosoeca difficile

description: Prosoeca difficile (Bequaert), comb. n.
 Stenobasiopteron difficile Bequaert, 1925: 11.
 Holotype ♀: Zimbabwe: Cloudlands, 6000’ [high altitude grassland] / Vumba Mts / ♀ S. Rhodesia / 6–17 April 1929 / Rhodesia Museum; Stenobasipteron / difficile / type ♀ J. Beq. / J. Bequaert det.; TYPE [rectangular red card]. The holotype (in NMBZ) is in good condition. There is no other type material.
 Discussion: In his original description, Bequaert remarked on the very close similarity between Stenobasipteron difficile and S. gracile, and listed seven characters which supposedly separated the species. This comparison is however incorrect, as Bequaert appears not to have examined the type material of S. gracile, and the material of S. gracile used for the comparison was misidentified as S. difficile (see above under S. arnoldi).
 I have examined the male syntype of S. gracile (a female syntype is the only other specimen in the type series), and there are several major characters separating it from S. difficile. The most important character is the development of vestiture on abdominal terga 3 and 4. S. difficile has obvious erect vestiture on these terga, unlike S. gracile which has inconspicuous, recumbent vestiture, characteristic of other Stenobasipteron species. As my diagnosis of Stenobasipteron includes only species with recumbent vestiture, I herewith transfer S. difficile to Prosoeca. It should be noted though that Prosoeca difficile, comb. n. does have a reduced alula, which was previously considered to characterise only Stenobasipteron species. The species are otherwise easily distinguished by colour characters. S. gracile is a pallid species with reddish­brown legs and very pale brown infuscated wings, whilst Prosoeca difficile is a dark species with yellow legs and relatively dark brown infuscated wings.
description: Published as part of Barraclough, David A., 2005, A review of the type material of the Southern African genus Stenobasipteron Lichtwardt, 1910 (Diptera: Nemestrinidae), with transfer of two species to Prosoeca Schiner, 1867, pp. 41-51 in Zootaxa 1094 (1) on page 49, DOI: 10.11646/zootaxa.1094.1.3, http://zenodo.org/record/5051350
Μία ψυχαναλυτική προσέγγιση του τραύματος και της λειτουργίας της αφήγησης στα μυθιστορήματα Πατρίδα από βαμβάκι της Έλενας Χουζούρη και Η αρραβωνιαστικιά του Αχιλλέα της Άλκης Ζέη
Creators: name: Ζάχου, Σωτηρία Γεωργίου
Publisher: name: Aristotle University of Thessaloniki
Year: 2021
Subjects: Τραύμα
Χυχανάλυση
Πολιτική εξορία-προσφυγιά
Trauma
Ppsychoanalysis
Political exile-refugee

description: Η παρούσα μεταπτυχιακή διπλωματική εργασία διερευνά τη σχέση ανάμεσα στο ψυχικό τραύμα των πολιτικών εξόριστων-προσφύγων του Εμφυλίου Πολέμου και τη λειτουργία της αφήγησης, όπως αυτή αναδεικνύεται μέσα από τη συγκριτική μελέτη των μυθιστορημάτων της Έλενας Χουζούρη Πατρίδα από βαμβάκι και της Άλκης Ζέη Η αρραβωνιαστικιά του Αχιλλέα. Η έρευνα στηρίζεται σε θεωρητικά εργαλεία που αντλούνται από το πεδίο της ψυχανάλυσης και ειδικότερα από τις θεωρίες του Sigmund Freud και του Jacques Lacan για το τραύμα και τον ρόλο της αφήγησης. Η εξέταση του τρόπου με τον οποίο το τραύμα των δύο πρωταγωνιστών αναπαρίσταται στα δύο μυθιστορήματα μέσω της αφήγησης-γλώσσας, αποτελεί βασικό οδηγό για την παραπάνω μελέτη. Μέσω της ανάλυσης προκύπτουν συμπεράσματα σχετικά με τη θεραπευτική λειτουργία της αφήγησης όσον αφορά τη διαχείριση του τραύματος, ενώ, παράλληλα, αναδεικνύεται και η επίδρασή του στη δόμηση της ταυτότητας των δύο κεντρικών χαρακτήρων.
description: This thesis explores the relationship between psychological trauma of political exiles-refugees of the Civil War and the function of narration, through the comparative study of Elena Chouzouri’s novel Cotton Motherland and Alki Zei’s Achilles’ Fiancée. The current study relies on theoretical tools deriving from psychoanalysis and, in particular, from the theories of Sigmund Freud and Jacques Lacan about trauma and the role of narration. Examining the way in which trauma is represented in the two novels through narration-language constitutes the fundamental axis of this study. Through the analysis conclusions are drawn on the healing function of narration regarding the management of trauma and its impact on the construction of identity of the two main characters.
Superconductive Excitations and the Infrared Vibronic Spectra of BSCCO
Creators: name: Phillips, J. C.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The oxygen dopant concentration dependence of the "quasiparticle" feature at 600-750 cm-1 of the infrared spectrum of Bi2Sr2CaCu2O8+delta (BSCCO), lying near and above the top of the host phonon spectrum at 600 cm-1, is strongly correlated with superconductivity. Using parameter-free topological methods, theory assigns this feature to split apical oxygen interstitials. It explains both the qualitative similarities and the quantitative differences between "quasiparticle" features identified in infrared and phtoemission data, as well as identifying new features in the infrared spectra.
description: 10 pages (jcphillips8@comcast.net)
ANTIOXIDANT COMPOSITION OF BY-PRODUCTS FROM THE CIDER INDUSTRY: APPLE POMACE
Creators: name: Pando Bedriñana, Rosa
name: Rodriguez Madrera, Roberto
name: Antón-Díaz, María José
name: Picinelli Lobo, Anna
Publisher: name: Zenodo
Year: 2024
Subjects: CID-4-PROFIT, cider by-products, apple pomace, bioactive compounds, bioeconomy

description: The optimization of an ultrasound-assisted extraction method revealed that ethanol concentration significantly influenced extraction efficiency, with higher ethanol levels favoring ursolic acid extraction but reducing total phenol yield. The optimal conditions were determined to be 68% ethanol, 5.1 minutes of extraction time, 90% amplitude, and 0.4 g of sample mass. This method was applied to whole apple pomace (WAP), apple peels (AP), and apple flesh (AF).
Molecular docking and molecular dynamics simulation approach to screen natural compounds for inhibition of Xanthomonas oryzae pv. Oryzae by targeting Peptide Deformylase
Creators: name: Tushar Joshi
name: Joshi, Tanuja
name: Sharma, Priyanka
name: Chandra, Subhash
name: Pande, Veena
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Xanthomonas oryzae pv. Oryzae (Xoo) causes bacterial leaf blight (BLB) of rice which results in a huge loss in production. Many chemicals are used to control BLB disease. However, these chemicals are toxic to the environments, animal as well as a human being. Thus, there is a demand to discover potential and safe natural pesticides to manage BLB disease successfully. Therefore, we screened a library of phytochemicals of different plants having antibacterial activity by targeting Peptide Deformylase (PDF) of Xoo using in silico techniques. A library of 318 phytochemicals was prepared and subjected to rigid and flexible molecular docking against PDF followed by molecular dynamics simulation and free energy analysis of protein-ligand complexes. The results of virtual screening showed that 14 compounds from different plants have good binding energy as compare to reference molecule (3R)-2,3-dihydro[1,3] thiazolo [3,2 a]benzimidazol-3-ol) (-7.7 kcal mol−1). Out of 14 hit compounds, eight compounds that were selected based on binding energy were analyzed by Molecular dynamic (MD) simulation. Analysis of MD simulation revealed that eight compounds namely; Bisdemethoxycurcumin, Rosmarinic acid, Piperanine, Dihydropiperlonguminine, Piperdardine, Dihydrocurcumin and Lonhumosides B achieved good stability during the 80 ns MD simulation at 300K in term of the RMSD. Further, we calculated RMSF, RG, SASA, and interaction energy after 40 ns due to showing the stability of complexes. From our results, we conclude that these natural compounds could inhibit Xoo by targeting PDF receptor and can be used as potential bactericidal candidates against BLB disease of rice against Xoo and other bacteria.
Effects of the On-Site Coulomb Repulsion in Double Exchange Magnets
Creators: name: Golosov, D. I.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We investigate the zero-temperature phase diagram and spin-wave properties of a double exchange magnet with on-site Hubbard repulsion. It is shown that even within a simple Hartree -- Fock approach this interaction (which is often omitted in theoretical treatments) leads to qualitatively important effects which are highly relevant in the context of experimental data for the colossal magnetoresistance compounds. These include the asymmetry of the doping dependence of spin stiffness, and the zone-boundary ``softening'' of spin wave dispersion. Effects of Hubbard repulsion on phase separation are analyzed as well. We also show that in the ferromagnetic phase, an unusual temperature-dependent effective electron-electron interaction arises at finite T. The mean-field scheme, however, does not yield the experimentally observed density of states depletion near the Fermi level. We speculate that proper treatment of electron-electron interactions may be necessary for understanding both this important feature and more generally the physics of colossal magnetoresistance phenomenon.
description: 17 pages, LaTeX-Revtex, 4 PostScript figures; misprints corrected