cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Heart Failure Stages among Older Adults in the Community: The Atherosclerosis Risk in Communities Study
Creators: name: Sueta, C.A
name: Shah, A.M
name: Wright, J.D
name: Kucharska-Newton, A
name: Mosley, T.H
name: Folsom, A.R
name: Konety, S
name: Solomon, S.D
name: Kitzman, D
name: Loehr, L.R
name: Matsushita, K
name: Heiss, G
name: Chang, P.P
name: Coresh, J
name: Claggett, B
Publisher: name: Lippincott Williams and Wilkins
Year: 2017

description: Background: Although heart failure (HF) disproportionately affects older adults, little data exist regarding the prevalence of American College of Cardiology/American Heart Association HF stages among older individuals in the community. Additionally, the role of contemporary measures of longitudinal strain and diastolic dysfunction in defining HF stages is unclear. Methods: HF stages were classified in 6118 participants in the Atherosclerosis Risk in Communities study (67-91 years of age) at the fifth study visit as follows: A (asymptomatic with HF risk factors but no cardiac structural or functional abnormalities), B (asymptomatic with structural abnormalities, defined as left ventricular hypertrophy, dilation or dysfunction, or significant valvular disease), C1 (clinical HF without prior hospitalization), and C2 (clinical HF with earlier hospitalization). Results: Using the traditional definitions of HF stages, only 5% of examined participants were free of HF risk factors or structural heart disease (Stage 0), 52% were categorized as Stage A, 30% Stage B, 7% Stage C1, and 6% Stage C2. Worse HF stage was associated with a greater risk of incident HF hospitalization or death at a median follow-up of 608 days. Left ventricular (LV) ejection fraction was preserved in 77% and 65% in Stages C1 and C2, respectively. Incorporation of longitudinal strain and diastolic dysfunction into the Stage B definition reclassified 14% of the sample from Stage A to B and improved the net reclassification index (P=0.028) and integrated discrimination index (P=0.016). Abnormal LV structure, systolic function (based on LV ejection fraction and longitudinal strain), and diastolic function (based on e', E/e', and left atrial volume index) were each independently and additively associated with risk of incident HF hospitalization or death in Stage A and B participants. Conclusions: The majority of older adults in the community are at risk for HF (Stages A or B), appreciably more compared with previous reports in younger community-based samples. LV ejection fraction is robustly preserved in at least two-thirds of older adults with prevalent HF (Stage C), highlighting the burden of HF with preserved LV ejection fraction in the elderly. LV diastolic function and longitudinal strain provide incremental prognostic value beyond conventional measures of LV structure and LV ejection fraction in identifying persons at risk for HF hospitalization or death.
Physics-informed neural wavefields with Gabor basis functions
Creators: name: Alkhalifah, Tariq
name: Huang, Xinquan
Publisher: name: arXiv
Year: 2023
Subjects: subject: Geophysics (physics.geo-ph)
subject: Artificial Intelligence (cs.AI)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Recently, Physics-Informed Neural Networks (PINNs) have gained significant attention for their versatile interpolation capabilities in solving partial differential equations (PDEs). Despite their potential, the training can be computationally demanding, especially for intricate functions like wavefields. This is primarily due to the neural-based (learned) basis functions, biased toward low frequencies, as they are dominated by polynomial calculations, which are not inherently wavefield-friendly. In response, we propose an approach to enhance the efficiency and accuracy of neural network wavefield solutions by modeling them as linear combinations of Gabor basis functions that satisfy the wave equation. Specifically, for the Helmholtz equation, we augment the fully connected neural network model with an adaptable Gabor layer constituting the final hidden layer, employing a weighted summation of these Gabor neurons to compute the predictions (output). These weights/coefficients of the Gabor functions are learned from the previous hidden layers that include nonlinear activation functions. To ensure the Gabor layer's utilization across the model space, we incorporate a smaller auxiliary network to forecast the center of each Gabor function based on input coordinates. Realistic assessments showcase the efficacy of this novel implementation compared to the vanilla PINN, particularly in scenarios involving high-frequencies and realistic models that are often challenging for PINNs.
Accuracy of Self-Reported Heart Failure. The Atherosclerosis Risk in Communities (ARIC) Study
Creators: name: Camplain, R
name: Layton, J.B
name: Loehr, L
name: Bertoni, A.G
name: Kucharska-Newton, A
name: Wruck, L
name: Heiss, G
name: Folsom, A.R
name: Keyserling, T.C
Publisher: name: Churchill Livingstone Inc.
Year: 2017

description: Objective The aim of this work was to estimate agreement of self-reported heart failure (HF) with physician-diagnosed HF and compare the prevalence of HF according to method of ascertainment. Methods and Results ARIC cohort members (60–83 years of age) were asked annually whether a physician indicated that they have HF. For those self-reporting HF, physicians were asked to confirm their patients' HF status. Physician-diagnosed HF included surveillance of hospitalized HF and hospitalized and outpatient HF identified in administrative claims databases. We estimated sensitivity, specificity, positive predicted value, kappa, prevalence and bias–adjusted kappa (PABAK), and prevalence. Compared with physician-diagnosed HF, sensitivity of self-report was low (28%–38%) and specificity was high (96%–97%). Agreement was poor (kappa 0.32–0.39) and increased when adjusted for prevalence and bias (PABAK 0.73–0.83). Prevalence of HF measured by self-report (9.0%), ARIC-classified hospitalizations (11.2%), and administrative hospitalization claims (12.7%) were similar. When outpatient HF claims were included, prevalence of HF increased to 18.6%. Conclusions For accurate estimates HF burden, self-reports of HF are best confirmed by means of appropriate diagnostic tests or medical records. Our results highlight the need for improved awareness and understanding of HF by patients, because accurate patient awareness of the diagnosis may enhance management of this common condition.
Additional file 1 of A clade of telosma mosaic virus from Thailand is undergoing geographical expansion and genetic differentiation in passionfruit of Vietnam and China
Creators: name: Yu, Chaowei
name: Lian, Qin
name: Lin, Huihuang
name: Chen, Lei
name: Lu, Yizhong
name: Zhai, Yingying
name: Han, Xing
name: Du, Zhenguo
name: Gao, Fangluan
name: Wu, Zujian
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. Figure S1. Maximum-likelihood phylogenetic tree based on the nucleotide sequences of the coat protein gene of Clade 1 TelMV. Ultrafast bootstrap support > 95% values are given at each node. TelMV isolates from different regions are indicated by a unique color. The bar represents the number of substitutions per site.
Detailed studies on the reduction of aliphatic 3-, 4-, 6-, and 13-oximino esters: Synthesis of novel isomeric amino esters, oximino alcohols, and amino alcohols
Creators: name: Küçük, Hatice Başpınar
name: Hasniye Yaşa
name: Yıldız, Tülay
name: Ayşe Sergüzel Yusufoğlu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Plant Biology

description: The preparation of novel 3-, 4-, 6-, and 13-amino-tetradecanoic acid methyl esters (2a–d) obtained by the reduction of 3-, 4-, 6-, and 13-oximino-tetradecanoic acid methyl esters (1a–d), was investigated. Oximino esters were reduced to afford the corresponding amino esters using NaBH4–ZrCl4 reducing system with good yields (58–82%). However, the reduction of oximino esters with LiAlH4 and BH3. Tetrahydrofuran gave the corresponding novel 3-, 4-, 6-, and 13-oximino alcohols (3a–d), and 3-, 4-, 6-, and 13-amino alcohols (4a–d) respectively with good chemical yields.
Remarks on effects of projective phase on eigenstate thermalization hypothesis
Creators: name: Fukushima, Osamu
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The existence of $p$-form symmetry in $(d+1)$-dimensional quantum field is known to always lead to the breakdown of the eigenstate thermalization hypothesis (ETH) for certain $(d-p)$-dimensional operators other than symmetry operators under some assumptions. The assumptions include the mixing of symmetry sectors within a given energy shell, which is rather challenging to verify because it requires information on the eigenstates in the middle of the spectrum. We reconsider this assumption from the viewpoint of projective representations to avoid this difficulty. In the case of $\mathbb{Z}_N$ symmetries, we can circumvent the difficulty by considering $\mathbb{Z}_N\times\mathbb{Z}_N$-symmetric theories with nontrivial projective phases, and perturbing the Hamiltonian while preserving one of the $\mathbb{Z}_N$ symmetries of our interest. We also perform numerical analyses for $(1+1)$-dimensional spin chains and the $(2+1)$-dimensional $\mathbb{Z}_2$ lattice gauge theory.
description: 23 pages, 5 figures; v3: minor modifications, published version in PTEP
VST++: Efficient and Stronger Visual Saliency Transformer
Creators: name: Liu, Nian
name: Luo, Ziyang
name: Zhang, Ni
name: Han, Junwei
Publisher: name: arXiv
Year: 2023
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: While previous CNN-based models have exhibited promising results for salient object detection (SOD), their ability to explore global long-range dependencies is restricted. Our previous work, the Visual Saliency Transformer (VST), addressed this constraint from a transformer-based sequence-to-sequence perspective, to unify RGB and RGB-D SOD. In VST, we developed a multi-task transformer decoder that concurrently predicts saliency and boundary outcomes in a pure transformer architecture. Moreover, we introduced a novel token upsampling method called reverse T2T for predicting a high-resolution saliency map effortlessly within transformer-based structures. Building upon the VST model, we further propose an efficient and stronger VST version in this work, i.e. VST++. To mitigate the computational costs of the VST model, we propose a Select-Integrate Attention (SIA) module, partitioning foreground into fine-grained segments and aggregating background information into a single coarse-grained token. To incorporate 3D depth information with low cost, we design a novel depth position encoding method tailored for depth maps. Furthermore, we introduce a token-supervised prediction loss to provide straightforward guidance for the task-related tokens. We evaluate our VST++ model across various transformer-based backbones on RGB, RGB-D, and RGB-T SOD benchmark datasets. Experimental results show that our model outperforms existing methods while achieving a 25% reduction in computational costs without significant performance compromise. The demonstrated strong ability for generalization, enhanced performance, and heightened efficiency of our VST++ model highlight its potential.
Contribution of medications and risk factors to QTc interval lengthening in the atherosclerosis risk in communities (ARIC) study
Creators: name: Aldemerdash, A
name: Thudium, E.M
name: Kucharska-Newton, A.M
name: Stearns, S.C
name: Rodgers, J.E
name: Soliman, E.Z
name: Sueta, C.A
name: Whitsel, E.A
name: Savitz, S.T
name: Tisdale, J.E
name: Alburikan, K.A
Publisher: name: Blackwell Publishing Ltd
Year: 2017

description: Rationale, aims, and objectives: Prolongation of the corrected QT (QTc) interval is associated with increased morbidity and mortality. The association between QTc interval–prolonging medications (QTPMs) and risk factors with magnitude of QTc interval lengthening is unknown. We examined the contribution of risk factors alone and in combination with QTPMs to QTc interval lengthening. Method: The Atherosclerosis Risk in Communities study assessed 15 792 participants with a resting, standard 12-lead electrocardiogram and ≥1 measure of QTc interval over 4 examinations at 3-year intervals (1987-1998). From 54 638 person-visits, we excluded participants with QRS ≥ 120 milliseconds (n = 2333 person-visits). We corrected the QT interval using the Bazett and Framingham formulas. We examined QTc lengthening using linear regression for 36 602 person-visit observations for 14 160 cohort members controlling for age ≥ 65 years, female sex, left ventricular hypertrophy, QTc > 500 milliseconds at the prior visit, and CredibleMeds categorized QTPMs (Known, Possible, or Conditional risk). We corrected standard errors for repeat observations per person. Results: Eighty percent of person-visits had at least one risk factor for QTc lengthening. Use of QTPMs increased over the 4 visits from 8% to 17%. Among persons not using QTPMs, history of prolonged QTc interval and female sex were associated with the greatest QTc lengthening, 39 and 12 milliseconds, respectively. In the absence of risk factors, Known QTPMs and ≥2 QTPMs were associated with modest but greater QTc lengthening than Possible or Conditional QTPMs. In the presence of risk factors, ≥2 QTPM further increased QTc lengthening. In combination with risk factors, the association of all QTPM categories with QTc lengthening was greater than QTPMs alone. Conclusion: Risk factors, particularly female sex and history of prolonged QTc interval, have stronger associations with QTc interval lengthening than any QTPM category alone. All QTPM categories augmented QTc interval lengthening associated with risk factors.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Cart. 189 (11 H 74), 316 folios, f. 0093r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: LaMOP
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0093r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome V, Archives départementales de la Côte-d'Or, Cart. 189 (11 H 74), 316 folios, f. 0093r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
The metabolic syndrome and risk of sudden cardiac death: The atherosclerosis risk in communities study
Creators: name: Gersh, B.J
name: Sotoodehnia, N
name: Prineas, R.J
name: Rosamond, W.R
name: Post, W.S
name: Mark, D.B
name: Curtis, L.H
name: Al-Khalidi, H.R
name: Hess, P.L
name: Lopes, R.D
name: Al-Khatib, S.M
name: Mulder, H
name: Kucharska-Newton, A
name: Friedman, D.J
Publisher: name: John Wiley and Sons Inc.
Year: 2017

description: Background--Prior studies have demonstrated a link between the metabolic syndrome and increased risk of cardiovascular mortality. Whether the metabolic syndrome is associated with sudden cardiac death is uncertain. Methods and Results--We characterized the relationship between sudden cardiac death and metabolic syndrome status among participants of the ARIC (Atherosclerosis Risk in Communities) Study (1987-2012) free of prevalent coronary heart disease or heart failure. Among 13 168 participants, 357 (2.7%) sudden cardiac deaths occurred during a median follow-up of 23.6 years. Participants with the metabolic syndrome (n=4444) had a higher cumulative incidence of sudden cardiac death than those without it (n=8724) (4.1% versus 2.3%, P < 0.001). After adjustment for participant demographics and clinical factors other than components of the metabolic syndrome, the metabolic syndrome was independently associated with sudden cardiac death (hazard ratio, 1.70, 95% confidence interval, 1.37-2.12, P < 0.001). This relationship was not modified by sex (interaction P=0.10) or race (interaction P=0.62) and was mediated by the metabolic syndrome criteria components. The risk of sudden cardiac death varied according to the number of metabolic syndrome components (hazard ratio 1.31 per additional component of the metabolic syndrome, 95% confidence interval, 1.19-1.44, P < 0.001). Of the 5 components, elevated blood pressure, impaired fasting glucose, and low high-density lipoprotein were independently associated with sudden cardiac death. Conclusions--We observed that the metabolic syndrome was associated with a significantly increased risk of sudden cardiac death irrespective of sex or race. The risk of sudden cardiac death was proportional to the number of metabolic syndrome components.
Cyclocondensation between fatty acid hydrazides and 1,1,1-trifluoro-4-alkoxy-3-alken-2-ones: Introducing a trifluoromethylated head onto fatty acid moieties
Creators: name: Wystan K. O. Teixeira
name: Gonçalves, Helena A.
name: Mello, Débora L. De
name: Sidnei Moura
name: Flores, Darlene C.
name: Flores, Alex F. C.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology

description: This paper reports the regioselective synthesis of new trifluoromethylated lipid derivatives, namely, 1-(5-hydroxy-5-trifluoromethyl-3-alkyl-4,5-dihydro-1H-pyrazol-1-yl)alkan-1-ones, through cyclocondensation reactions between a series of fatty hydrazides (palmitoyl, stearoyl, and oleoyl hydrazides) obtained from fatty acids from renewable resources (1,1,1-trifluoro-4-alkoxy-3-alken-2-ones [F3CC(O)CH˭C(R1)OR, where R1 = H and R˭Et; R1 = –(CH2)6CH3, –(CH2)6CH3, –(CH2)8CH3, –(CH2)9CH3, –(CH2)10CH3, –(CH2)12CH3, –(CH2)2Ph], and R˭Me). Experimental observations showed that the lipophilic characteristic of 5-hydroxy-5-trifluoromethyl-4,5-dihydro-1H-pyrazoles (5–7) prevent the acid catalyzed dehydration to aromatization of 1H-pyrazole ring, although in some cyclocondensations a proportion of the aromatic derivative 1-(5-trifluoromethyl-3-alkyl-1H-pyrazol-1-yl)alkan-1-one was obtained. All products were characterized using multinuclear (1H, 13C, 19F) NMR spectroscopy.
Data Sources for Administrative Justice Research: a Preliminary Scoping Report (2017)
Creators: name: Kakia Chatsiou
name: Bondy, Varda
name: Doyle, Margaret
name: Sena, Vania
name: Sunkin, Maurice
Publisher: name: figshare
Year: 2017
Subjects: subject: 160509 Public Administration
subject: FOS: Political science
subject: 80707 Organisation of Information and Knowledge Resources
subject: FOS: Media and communications

description: This report presents a preliminary scoping study identifying data sources related to administrative justice research across the public and private sectors and determining what is available and how it is collected, stored and made available, and how these sources might fulfill researchers’ need for data analysis.
The residual flow in well-optimized stellarators
Creators: name: Plunk, G. G.
name: Helander, P.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: The gyrokinetic theory of the residual flow, in the electrostatic limit, is revisited, with optimized stellarators in mind. We consider general initial conditions for the problem, and identify cases that lead to a non-zonal residual electrostatic potential, i.e. one having a significant component that varies within a flux surface. We investigate the behavior of the ``intermediate residual'' in stellarators, a measure of the flow that remains after geodesic acoustic modes have damped away, but before the action of the slower damping that is caused by unconfined particle orbits. The case of a quasi-isodynamic stellarator is identified as having a particularly large such residual, owing to the small orbit width achieved by optimization.
A detailed studies on the reduction of aliphatic 3-, 4-, 6- and 13-oximino esters: Synthesis of novel isomeric amino esters, oximino alcohols, and amino alcohols
Creators: name: Küçük, Hatice Başpınar
name: Hasniye Yaşa
name: Yıldız, Tülay
name: Ayşe Sergüzel Yusufoğlu
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Plant Biology

description: The preparation of novel 3-, 4-, 6-, and 13-amino-tetradecanoic acid methyl esters (2a-d) obtained by the reduction of 3-, 4-, 6-, and 13-oximino-tetradecanoic acid methyl esters (1a-d), was investigated. Oximino esters were reduced to afford the corresponding amino esters using NaBH4-ZrCl4 reducing system with good yields (58-82%). On the other hand, the reduction of oximino esters with LiAlH4 and BH3. THF gave the corresponding novel 3-, 4-, 6-, and 13-oximino alcohols (3a-d), and 3-, 4-, 6-, and 13-amino alcohols (4a-d) respectively with good chemical yields.
Evolving Landscapes and Changing Architectures in Modern Japanese Urban Environment
Creators: name: Pernice, Raffaele
Publisher: name: figshare
Year: 2022
Subjects: subject: 120101 Architectural Design
subject: FOS: Arts (arts, history of arts, performing arts, music)
subject: 120102 Architectural Heritage and Conservation
subject: FOS: Civil engineering
subject: 120103 Architectural History and Theory
subject: 120301 Design History and Theory
subject: 120502 History and Theory of the Built Environment (excl. Architecture)
subject: FOS: Social and economic geography
subject: 120508 Urban Design
subject: 120507 Urban Analysis and Development

description: 'The Mediated City Los Angeles Conference' - Architecture MPS, Woodbury University, School of Media, Culture and Design, Los Angeles (USA), 1-4 October 2014

The aim of this short paper is to introduce some open-ended considerations on the process of formation and evolution of the modern Japanese urban landscape in the second half of the 20 th century, a process that unfolded since the end of the WWII and heavily relied on the outcomes of the economic growth and social mutation based on the technological innovation and infrastructural development. The peculiar and distinctive urban landscape of modern Japanese cities resulted by the combination of innovation of foreign origins and also by the re-interpretation of some elements of the local culture and aesthetic tradition. The extreme fragmentation and the patchwork like nature of the urban tissue of most of the Japanese cites is linked to the frantic pace of changes and the overlapping of eclectic forms, dense functions and mixed activities which combine and integrate with the use of a new aesthetic language based on the acceptance of the power of change of the latest technologies.
Cardiovascular Dysfunction and Frailty among Older Adults in the Community: The ARIC Study
Creators: name: Skali, H
name: Solomon, S.D
name: Kitzman, D
name: Wagenknecht, L.E
name: Heiss, G
name: Palta, P
name: Butler, K
name: Kucharska-Newton, A
name: Nadruz, W
name: Shah, A.M
name: Griswold, M.E
name: Windham, B.G
Publisher: name: Oxford University Press
Year: 2017

description: Background: The contribution of cardiovascular dysfunction to frailty in older adults is uncertain. This study aimed to define the relationship between frailty and cardiovascular structure and function, and determine whether these associations are independent of coexisting abnormalities in other organ systems. Methods: We studied 3,991 older adults (mean age 75.6 - 5.0 years; 59% female) from the Atherosclerosis Risk in Communities (ARIC) Study in whom the following six organ systems were uniformly assessed: cardiac (by echocardiography), vascular (by ankle-brachial-index and pulse-wave-velocity), pulmonary (by spirometry), renal (by estimated glomerular filtration rate), hematologic (by hemoglobin), and adipose (by body mass index and bioimpedance). Frailty was defined by the presence of ?3 of the following: low strength, low energy, slowed motor performance, low physical activity, or unintentional weight loss. Results: Two hundred eleven (5.3%) participants were frail. In multivariable analyses adjusted for demographics, diabetes, hypertension, and measures of other organ system function, frailty was independently and additively associated with left ventricular hypertrophy (odds ratio [OR] = 1.72; 95% confidence interval [CI] = 1.30-2.40), reduced global longitudinal strain (reflecting systolic function; OR = 1.68; 95% CI = 1.16-2.44), and greater left atrial volume index (reflecting diastolic function; OR = 1.60; 95% CI = 1.13-2.27), which together demonstrated the greatest association with frailty (OR = 2.10; 95% CI = 1.57-2.82) of the systems studied. Lower magnitude associations were observed for vascular and pulmonary abnormalities, anemia, and impaired renal function. Cardiovascular abnormalities remained associated with frailty after excluding participants with prevalent cardiovascular disease. Conclusions: Abnormalities of cardiac structure and function are independently associated with frailty, and together show the greatest association with frailty among the organ systems studied.
title: ADCO, Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Cart. 172 (11 H 69), 115 folios, f. 0232
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0232, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0232, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Misclassification of incident hospitalized and outpatient heart failure in administrative claims data: the Atherosclerosis Risk in Communities (ARIC) study
Creators: name: Alonso, A
name: Wright, J.D
name: Cuthbertson, C.C
name: Kucharska-Newton, A
name: Heiss, G
name: Camplain, R
Publisher: name: John Wiley and Sons Ltd
Year: 2017

description: Purpose: The aim of this study was to quantify the influence of the length of the look-back period on misclassification of heart failure (HF) incidence in Medicare claims available for participants of a population-based cohort. Methods: Atherosclerosis Risk in Communities participants with ≥3 years of continuous fee-for-service Medicare enrollment from 2000 to 2012 was assigned an index date 36 months after enrollment separating the time-in-observation period into the look-back and the incidence periods. Incident HF events were identified using ICD-9-CM code algorithms as the first observed hospitalization claim or the second of two HF outpatient claims occurring within 12 months. Using 36 months as a referent, the look-back period was reduced by 6-month increments. For each look-back period, we calculated the incidence rate, percent of prevalent HF events misclassified as incident, and loss in sample size. Results: We identified 9568 Atherosclerosis Risk in Communities participants at risk for HF. For hospitalized and outpatient HF, the number of events misclassified as incident increased, and the total number of incident events decreased with increased length of the look-back period. The incident rate (per 1000 person years) decreased with increased length of the look-back period from 6 to 36 months and had a greater impact on outpatient HF; for example, from 11.2 to 10.6 for ICD-9-CM 428.xx hospitalization in the primary position and 10.5 to 7.9 for outpatient HF. Conclusion: Our estimates can be used to optimize trade-offs between the degree of misclassification and number of events in the estimation of incident HF from administrative claims data, as pertinent to different study questions.
Supplementary file information for Continuous synthesis of PVP stabilized biocompatible gold nanoparticles with a controlled size using a 3D glass capillary microfluidic device
Creators: name: Monalie Bandulasena
name: Vladisavljevic, Goran
name: Omololu Odunmbaku
name: Benyahia, Brahim
Publisher: name: Loughborough University
Year: 2017
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Supplementary file information for Continuous synthesis of PVP stabilized biocompatible gold nanoparticles with a controlled size using a 3D glass capillary microfluidic deviceA reliable glass capillary microfluidic method was developed for a continuous production of well-controlled gold nanoparticles (AuNPs) capped with polyvinylpyrrolidone (PVP) of different molecular weights (PVP K15, PVP K30 and PVP K90). A two-phase co-flow glass capillary microfluidic device with an injection orifice diameter ranging between 100 and 240 µm was used to synthesise 100–240 µm was used to synthesise AuNPs via the chemical reduction between tetrachloroaurate trihydrate (HAuCl4·3H2O) and ascorbic acid. AuNPs with an average diameter between 48 and 135 nm were synthesised, as determined by DLS measurements. Decreasing the injection orifice diameter, increasing the flow rate of ascorbic acid stream and its pH resulted in smaller AuNPs. The polydispersity index (PDI) was found to be independent on the injection orifice diameter or the molecular weight of PVP, but increased with the increase of flow rate and the pH of ascorbic acid stream. The stability study over 6-week period confirmed that PVP K30 with an average Mw of 40000 g/mol was the best capping agent to synthesize and stabilise smaller AuNPs. The reactor fouling due to deposition of AuNPs on reactor walls and orifices was mitigated by hydrophobization of reactor/capillary walls with octadecyltrimethoxisilane and the use of ascorbic acid solution of higher pH.
Spousal influence on physical activity in middle-aged and older adults
Creators: name: Kucharska-Newton, A
name: Coresh, J
name: Selvin, E
name: Godino, J.G
name: Cobb, L.K
name: Koton, S
Publisher: name: Oxford University Press
Year: 2016

description: Low physical activity levels are a public health concern. Few studies have assessed the concordance of physical activity change among spouses. We studied this concordance during a 6-year period (baseline: 1987-1989; follow-up: 1993-1995) in 3,261 spousal pairs from the US-based Atherosclerosis Risk in Communities (ARIC) Study. Linear regression was used to examine the association between change in individuals' sport/exercise and leisure physical activity indices (ranging from 1 (low) to 5 (high)) and change in his or her spouse's indices. The association between individual and spousal changes in meeting physical activity recommendations was assessed with logistic regression. Individual changes in the sport/exercise and leisure indices were positively associated with spousal changes. For every standard deviation increase in their wives' sport/exercise index, men's exercise index increased by 0.09 (95% confidence interval: 0.05, 0.12) standard deviation; for every standard deviation increase in their wives' leisure index, men's leisure index increased by 0.08 standard deviation. Results were similar for women. Individuals had higher odds of meeting physical activity recommendations if their spouse met recommendations at both visits or just follow-up. In conclusion, changes in an individual's physical activity are positively associated with changes in his or her spouse's physical activity. Physical activity promotion efforts should consider targeting couples.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 1126
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1126, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 1126, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study
Creators: name: Koh, W.J.H
name: Polak, J.F
name: Delaney, J.A
name: Kucharska-Newton, A
name: Halm, E.A
name: Hirsch, C.H
name: Longstreth, W.T
name: Curtis, L
name: Mukamal, K.J
name: Garg, P.K
Publisher: name: S. Karger AG
Year: 2016

description: Background: Population-based risk factors for carotid artery revascularization are not known. We investigated the association between demographic and clinical characteristics and incident carotid artery revascularization in a cohort of older adults. Methods: Among Cardiovascular Health Study participants, a population-based cohort of 5,888 adults aged 65 years or older enrolled in two waves (1989-1990 and 1992-1993), 5,107 participants without a prior history of carotid endarterectomy (CEA) or cerebrovascular disease had a carotid ultrasound at baseline and were included in these analyses. Cox proportional hazards multivariable analysis was used to determine independent risk factors for incident carotid artery revascularization. Results: Over a mean follow-up of 13.5 years, 141 participants underwent carotid artery revascularization, 97% were CEA. Baseline degree of stenosis and incident ischemic cerebral events occurring during follow-up were the strongest predictors of incident revascularization. After adjustment for these, factors independently associated with an increased risk of incident revascularization were: hypertension (HR 1.53; 95% CI: 1.05-2.23), peripheral arterial disease (HR 2.57; 95% CI: 1.34-4.93), and low-density lipoprotein cholesterol (HR 1.23 per standard deviation [SD] increment [35.4 mg/dL]; 95% CI: 1.04-1.46). Factors independently associated with a lower risk of incident revascularization were: female gender (HR 0.51; 95% CI: 0.34-0.77) and older age (HR 0.69 per SD increment [5.5 years]; 95% CI: 0.56-0.86). Conclusions: Even after accounting for carotid stenosis and incident cerebral ischemic events, carotid revascularization is related to age, gender, and cardiovascular risk factors. Further study of these demographic disparities and the role of risk factor control is warranted.
ERGO-ML: Comparing IllustrisTNG and HSC galaxy images via contrastive learning
Creators: name: Eisert, Lukas
name: Bottrell, Connor
name: Pillepich, Annalisa
name: Shimakawa, Rhythm
name: Rodriguez-Gomez, Vicente
name: Nelson, Dylan
name: Angeloudi, Eirini
name: Huertas-Company, Marc
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Modern cosmological hydrodynamical galaxy simulations provide tens of thousands of reasonably realistic synthetic galaxies across cosmic time. However, quantitatively assessing the level of realism of simulated universes in comparison to the real one is difficult. In this paper of the ERGO-ML series (Extracting Reality from Galaxy Observables with Machine Learning), we utilize contrastive learning to directly compare a large sample of simulated and observed galaxies based on their stellar-light images. This eliminates the need to specify summary statistics and allows to exploit the whole information content of the observations. We produce survey-realistic galaxy mock datasets resembling real Hyper Suprime-Cam (HSC) observations using the cosmological simulations TNG50 and TNG100. Our focus is on galaxies with stellar masses between $10^9$ and $10^{12} M_\odot$ at $z=0.1-0.4$. This allows us to evaluate the realism of the simulated TNG galaxies in comparison to actual HSC observations. We apply the self-supervised contrastive learning method NNCLR to the images from both simulated and observed datasets (g, r, i - bands). This results in a 256-dimensional representation space, encoding all relevant observable galaxy properties. Firstly, this allows us to identify simulated galaxies that closely resemble real ones by seeking similar images in this multi-dimensional space. Even more powerful, we quantify the alignment between the representations of these two image sets, finding that the majority ($\gtrsim 70$ per cent) of the TNG galaxies align well with observed HSC images. However, a subset of simulated galaxies with larger sizes, steeper Sersic profiles, smaller Sersic ellipticities, and larger asymmetries appears unrealistic. We also demonstrate the utility of our derived image representations by inferring properties of real HSC galaxies using simulated TNG galaxies as the ground truth.
description: 26 pages, 17 figures. Comments are welcome. Highlights in Fig. 3, 7 and 13
Mind the Gap: Hospitalizations from Multiple Sources in a Longitudinal Study
Creators: name: Groves, J.S
name: Stearns, S.C
name: Kucharska-Newton, A.M
name: Savitz, S.T
name: Bengtson, L.G.S
name: Wruck, L
Publisher: name: Elsevier Ltd
Year: 2017

description: Background Medicare claims and prospective studies with self-reported utilization are important sources of hospitalization data for epidemiologic and outcomes research. Objectives To assess the concordance of Medicare claims merged with interview-based surveillance data to determine factors associated with source completeness. Methods The Atherosclerosis Risk in Communities (ARIC) study recruited 15,792 cohort participants aged 45 to 64 years in the period 1987 to 1989 from four communities. Hospitalization records obtained through cohort report and hospital record abstraction were matched to Medicare inpatient records (MedPAR) from 2006 to 2011. Factors associated with concordance were assessed graphically and using multinomial logit regression. Results Among fee-for-service enrollees, MedPAR and ARIC hospitalizations matched approximately 67% of the time. For Medicare Advantage enrollees, completeness increased after initiation of hospital financial incentives in 2008 to submit shadow bills for Medicare Advantage enrollees. Concordance varied by geographic site, age, veteran status, proximity to death, study attrition, and whether hospitalizations were within ARIC catchment areas. Conclusions ARIC and MedPAR records had good concordance among fee-for-service enrollees, but many hospitalizations were available from only one source. MedPAR hospital records may be missing for veterans or observation stays. Maintaining study participation increases stay completeness, but new sources such as electronic health records may be more efficient than surveillance for mobile elderly populations.
Supplementary Text from Integrating neural operators with diffusion models improves spectral representation in turbulence modelling
Creators: name: Oommen, Vivek
name: Bora, Aniruddha
name: Zhang, Zhen
name: Karniadakis, George Em
Publisher: name: The Royal Society
Year: 2025
Subjects: classificationCode: 401299
subject: Fluid mechanics and thermal engineering not elsewhere classified
classificationCode: 401799
subject: Mechanical engineering not elsewhere classified
classificationCode: 460299
subject: Artificial intelligence not elsewhere classified

description: Proper Orthogonal Decomposition Analysis
Additional file 2 of Differential richness inference for 16S rRNA marker gene surveys
Creators: name: Kumar, M. Senthil
name: Slud, Eric V.
name: Hehnly, Christine
name: Zhang, Lijun
name: Broach, James
name: Irizarry, Rafael A.
name: Schiff, Steven J.
name: Paulson, Joseph N.
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Presents supplementary figures S1-S22. Related literature references are contained within the note.
title: Geo-Rational - Ethics in/for the Geosciences
Creators: name:  Bohle ,  Martin
Publisher: name: Deutsche Geologische Gesellschaft - Geologische Vereinigung e.V. (DGGV)
Year: 2021

description: Geosciences co-shape the human niche, that is, the planetary network of twinned natural and cultural landscapes. Bundled by global supply chains, human agents (individuals, groups, institutions, corporations) alter the human niche through engineering, production processes and consumption patterns [1]. The resulting [planetary] social-ecological systems exhibit complex-adaptive dynamics. In turn, human agents face system features like counter-intuitive behaviour, irreversible path-dependency and multi-facet values and interests. Geoethical thinking explores cultural substrates that nurture human agents' skills and operational circumstances when facing suchlike ["wicked"] system features. Geoethics is about responsible geosciences. Initially, geoscientists conceived geoethics for geoscientists, that is, their professional functions in various societal contexts [2]. Subsequently, geoethics evolved and diversified, including a plurality of value systems. For example, incorporating Kohlberg's hierarchy of moral adequacy and Jonas's imperative of responsibility into geoethics leads to formulating a 'geo-rationale', namely, to act with: 'agent-centricity, virtue-focus, responsibility focus, knowledge-based, all-actor-inclusiveness, and universal-rights based'. Irrespectively of different settings, geoethics offers (philosophical) work-horses when handling geoscience challenges in their societal contexts; for example, [nuclear] repositories. Geoethics takes the shape of an epistemic, moral hybrid for citizens interacting with the Earth system [3]. 1. Rosol C, Nelson S, Renn J (2017) Introduction: In the machine room of the Anthropocene. Anthr Rev 4:2–8. https://doi.org/10.1177/2053019617701165 2. Peppoloni S, Di Capua G (2015) Geoethics, the role and responsibility of geoscientists, Lyell Coll. Geological Society of London, London 3. Bohle M, Marone E (2021) Geoethics, a Branding for Sustainable Practices. Sustainability 13:895. https://doi.org/10.3390/su13020895
Supplementary Information files for Prediction and control of drop formation modes in microfluidic generation of double emulsions by single-step emulsification
Creators: name: Nabavi, Seyed Ali
name: Vladisavljevic, Goran
name: Monalie Bandulasena
name: Tash, Omid Arjmandi
name: Manović, Vasilije
Publisher: name: Loughborough University
Year: 2017
Subjects: subject: 90499 Chemical Engineering not elsewhere classified
subject: FOS: Chemical engineering

description: Supplementary Information files for Prediction and control of drop formation modes in microfluidic generation of double emulsions by single-step emulsificationHypothesis - Predicting formation mode of double emulsion drops in microfluidic emulsification is crucial for controlling the drop size and morphology. Experiments and modelling - A three-phase Volume of Fluid-Continuum Surface Force (VOF–CSF) model was developed, validated with analytical solutions, and used to investigate drop formation in different regimes. Experimental investigations were done using a glue-free demountable glass capillary device with a true axisymmetric geometry, capable of readjusting the distance between the two inner capillaries during operation. Findings - A non-dimensional parameter (ζ) for prediction of double emulsion formation mode as a function of the capillary numbers of all fluids and device geometry was developed and its critical values were determined using simulation and experimental data. At logζ > 5.7, drops were formed in dripping mode; the widening jetting occurred at 5 < logζ < 5.7; while the narrowing jetting was observed at logζ < 5. The ζ criterion was correlated with the ratio of the breakup length to drop diameter. The transition from widening to narrowing jetting was achieved by increasing the outer fluid flow rate at the high capillary number of the inner fluid. The drop size was reduced by reducing the distance between the two inner capillaries and the minimum drop size was achieved when the distance between the capillaries was zero.