cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
On the time lags of the LIGO signals
Creators: name: Creswell, James
name: von Hausegger, Sebastian
name: Jackson, Andrew D.
name: Liu, Hao
name: Naselsky, Pavel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: To date, the LIGO collaboration has detected three gravitational wave (GW) events appearing in both its Hanford and Livingston detectors. In this article we reexamine the LIGO data with regard to correlations between the two detectors. With special focus on GW150914, we report correlations in the detector noise which, at the time of the event, happen to be maximized for the same time lag as that found for the event itself. Specifically, we analyze correlations in the calibration lines in the vicinity of 35\,Hz as well as the residual noise in the data after subtraction of the best-fit theoretical templates. The residual noise for the other two events, GW151226 and GW170104, exhibits similar behavior. A clear distinction between signal and noise therefore remains to be established in order to determine the contribution of gravitational waves to the detected signals.
description: The body of the current version is essentially identical to the previous one submitted to arxiv and JCAP. In order to meet the various suggestions of the referees, we have included an extended and detailed Appendix. This Appendix also contains significant new results that provide additional support for our conclusions. This version of our manuscript has been accepted for publication by JCAP
Editorial: Preservação digital e sua prática nos diversos campos dos saberes
Creators: name: Santos, Gildenir Carolino
name: Ferreira, Danielle Thiago
Publisher: name: figshare
Year: 2018
Subjects: subject: 80706 Librarianship
subject: FOS: Media and communications
subject: Library and Information Studies

description: Nesse número, trazemos como temática “Preservação digital e sua prática nos diversos campos dos saberes” com o propósito de enriquecer e contribuir para as iniciativas e práticas sobre a preservação digital brasileira, em grande parte promovida pela Rede Brasileira de Serviços de Preservação Digital – Rede Cariniana.
title: ADCO, Ordre cistercien : comptes. Secundum registrum monasteriorum ordinis Cisterciensis (1354), Cart. 170 (11 H 1159), f. 00059
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Ordre cistercien : comptes. Secundum registrum monasteriorum ordinis Cisterciensis (1354), Archives départementales de la Côte-d'Or, Cart. 170 (11 H 1159), f. 00059, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien : comptes. Secundum registrum monasteriorum ordinis Cisterciensis (1354), Archives départementales de la Côte-d'Or, Cart. 170 (11 H 1159), f. 00059, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Phytochemical, Antioxidant, Antimicrobial, and Protein Binding Qualities of Hydro-ethanolic Extract of Tinospora cordifolia
Creators: name: Kumar, Vijay
name: Singh, Simranjeet
name: Singh, Arjun
name: Dixit, Amit Kumar
name: Srivastava, Bhavana
name: Sidhu, Gurpreet Kaur
name: Singh, Ravindra
name: Meena, Ajay Kumar
name: Singh, Rajesh Pratap
name: Subhose, Varanasi
name: Prakash, Om
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Plant Biology

description: The study was performed to check the chemical, antioxidant, antimicrobial and protein binding qualities of the hydro-ethanolic extract of Tinospora cordifolia (TC). In qualitative and quantitative analysis of extract, the major compounds were tinocordioside, cordifolide A, palmatine, quercetin, β-sitosterol, heptacosanol, and syringin. Hydro-ethanolic extract of TC exhibited low antibacterial and antifungal activities. Excellent antioxidant activities (60–80 %) were noticed for various antioxidant assays viz DPPH (2,2-diphenyl-1-picrylhydrazyl), MC (Metal chelating), FRAP (Ferric reducing), SA (Superoxide radical), and NO (Nitric oxide). Total phenolic content (TPC) and total flavanoids content (TFC) of the extract was 2.38±0.15 mg/g (expressed in equivalents to gallic acid) and 18.91±0.21 mg (expressed in equivalents quercetin) respectively. Moreover, at p < 0.05, significant linear correlation was noticed between the TFC/TPC and antioxidant activities favoured which highlights the medicinal property of TC. Protein binding assay was performed and an observed binding constant (1.03±0.92×10-5 μM-1) was almost close to control (aspirin). Anti-inflammatory assay revealed potent anti-inflammatory activity of hydro-alcoholic extract of TC. These significant findings of TC may provide compelling scientific evidence of its therapeutic potential.
Gravitational leptogenesis in Natural Inflation
Creators: name: Papageorgiou, Alexandros
name: Peloso, Marco
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the gravitational leptogenesis generated from the parity-violating gravitational waves sourced by an abelian gauge field coupled to a pseudo-scalar inflation. We show that, once the CMB bound on the tensor-to-scalar ratio is enforced, the lepton asymmetry produced by this mechanism during inflation is too small to account for the observed baryon asymmetry of the universe, irrespectively of the inflaton potential, the strength of its coupling to the gauge field, and the details of reheating.
description: 18 pages, 2 figures; published version
Measure Theory and Integration By and For the Learner
Creators: name: Lo, Gane Samb
name: Niang, Aladji Babacar
Publisher: name: arXiv
Year: 2017
Subjects: subject: History and Overview (math.HO)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 28A05, 28A10, 28A12, 28A20, 28A25, 28A33, 28A35

description: Measure Theory and Integration is exposed with the clear aim to help beginning learners to perfectly master its essence. In opposition of a delivery of the contents in an academic and vertical course, the knowledge is broken into exercises which are left to the learners for solutions. Hints are present at any corner to help readers to achieve the solutions. In that way, the knowledge is constructed by the readers by summarizing the results of one or a group of exercises. Each chapter is organized into Summary documents which contain the knowledge, Discovery documents which give the learner the opportunity to extract the knowledge himself through exercises and into Solution Documents which offer detailed answers for the exercises. Exceptionally, a few number of results (A key lemma related the justification of definition of the integral of a non-negative function, the Caratheodory's theorem and the Lebesgue-Stieljes measure on $\mathbb{R}^d$) are presented in appendix documents and given for reading in small groups. The full theory is presented in the described way. We highly expect that any student who goes through the materials, alone or in a small group or under the supervision of an assistant will gain a very solid knowledge in the subject and by the way ensure a sound foundation for studying disciplines such as Probability Theory, Statistics, Functional Analysis, etc. The materials have been successfully used as such in normal real analysis classes several times.
description: 715 pages
title: Emerging concepts and tools in cell mechanomemory
Creators: name: Lele, Tanmay
name: Brock, Amy
name: Peyton, Shelly
Publisher: name: University of Massachusetts Amherst
Year: 2020
Subjects: subject: biomaterials
subject: cancer
subject: mechanobiology

description: Studying a cell’s ability to sense and respond to mechanical cues has emerged as a field unto itself over the last several decades, and this research area is now populated by engineers and biologists alike. As just one example of this cell mechanosensing, fibroblasts on soft substrates have slower growth rates, smaller spread areas, lower traction forces, and slower migration speeds compared to cells on stiff substrates. This phenomenon is not unique to fibroblasts, as these behaviors, and others, on soft substrates has been shown across a variety of cell types, and reproduced in many different labs. Thus far, the field has focused on discerning the mechanisms of cell mechanosensing through ion channels, focal adhesions and integrin-binding sites to the ECM, and the cell cytoskeleton. A relatively new concept in the field is that of mechanical memory, which refers to persistent effects of mechanical stimuli long after they have been removed from said stimulus. Here, we review this literature, provide an overview of emerging substrate fabrication approaches likely to be helpful for the field, and suggest the adaption of genetic tools for studying mechanical memory.
A Nonlinear Kernel Support Matrix Machine for Matrix Learning
Creators: name: Ye, Yunfei
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: In many problems of supervised tensor learning (STL), real world data such as face images or MRI scans are naturally represented as matrices, which are also called as second order tensors. Most existing classifiers based on tensor representation, such as support tensor machine (STM) need to solve iteratively which occupy much time and may suffer from local minima. In this paper, we present a kernel support matrix machine (KSMM) to perform supervised learning when data are represented as matrices. KSMM is a general framework for the construction of matrix-based hyperplane to exploit structural information. We analyze a unifying optimization problem for which we propose an asymptotically convergent algorithm. Theoretical analysis for the generalization bounds is derived based on Rademacher complexity with respect to a probability distribution. We demonstrate the merits of the proposed method by exhaustive experiments on both simulation study and a number of real-word datasets from a variety of application domains.
Acquired Data Services: Challenges and Opportunities for Libraries
Creators: name: Kulp, Christina
Publisher: name: Zenodo
Year: 2019
Subjects: acquired data
data services
libraries

description: There are many disciplines where researchers are dependent on acquired data (or data created by others) for their own research and work products, like economics. In 2015, the Federal Reserve Bank of Kansas City hired its first dedicated data services librarian in order to better manage the complex process of procuring data for research economists. Acquired data presents its own unique challenges that do not exist for data generated by researchers. For example, it is important for researchers to think of their data needs first and engage with the data services librarian early in their project so there is time for the acquisition process to navigate numerous budgeting and approval hurdles. Another important process is clearly communicating the terms and conditions that dictate what the research can or cannot do with the data. Libraries who hope to expand services into acquired data management could be involved at multiple stages in the lifecycle in supporting the discovery, procurement, ingesting, governing, accessing, managing, and potentially preserving of proprietary data. This presentation will cover a variety of factors libraries should consider, from the first step to the last, when taking on the service of acquiring data on behalf of researchers.
Kinematic space for conical defects
Creators: name: Cresswell, Jesse C.
name: Peet, Amanda W.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Kinematic space can be used as an intermediate step in the AdS/CFT dictionary and lends itself naturally to the description of diffeomorphism invariant quantities. From the bulk it has been defined as the space of boundary anchored geodesics, and from the boundary as the space of pairs of CFT points. When the bulk is not globally AdS$_3$ the appearance of non-minimal geodesics leads to ambiguities in these definitions. In this work conical defect spacetimes are considered as an example where non-minimal geodesics are common. From the bulk it is found that the conical defect kinematic space can be obtained from the AdS$_3$ kinematic space by the same quotient under which one obtains the defect from AdS$_3$. The resulting kinematic space is one of many equivalent fundamental regions. From the boundary the conical defect kinematic space can be determined by breaking up OPE blocks into contributions from individual bulk geodesics. A duality is established between partial OPE blocks and bulk fields integrated over individual geodesics, minimal or non-minimal.
description: 29 pages, 9 figures. As published in JHEP
Memories of Maurice Poupard
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: My father considered himself elderly when he was called up compared to his colleagues. I think he was 28 or 29. It was at the end of the war in 1946 and he was billeted to Shepherd's Bush, London to decommission vehicles. He was an engineer by trade. His home was Southampton and he hated being away from my mum. So, every Friday night he would get on an old bike and cycle to Southampton and then cycle back on a Sunday night ready for his week's duties. It would have been about 60 miles. Postwar - A few years later he was going to Brisbane (about 1950). They asked for engineers, so we got off at Perth. Within a week my mum was dead, and she died from the blood condition, Addison's disease. My mother was called Beryl Wingrove.My father died in 2012 aged 90 years.
A new flavonoid derivative and a new 5-hydroxyanthranilic acid derivative from the sea urchin-derived Streptomyces sp. HDa1
Creators: name: Guo, Zhi-Kai
name: Wang, Rong
name: Liu, Tian-Mi
name: Chen, Fu-Xiao
name: Yang, Ming-Qiu
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Neuroscience
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Virology

description: One new flavonoid derivative flavoside A (1), one new 5-hydroxyanthranilic acid derivative crassilin (2), along with the known angucyclinone PD116740 (3) and oxachelin (4), was isolated from the EtOAc extract of the fermentation broth of the sea urchin (Anthocidaris crassispina)-derived actinobacterium, Streptomyces sp. HD01. The structures of these compounds were established on the basis of their HR-ESI-MS and NMR spectroscopic data. All of these compounds were assessed for their antibacterial activity.
Memories of Peter Reginald Conway
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Please note this submission contains links to websites that are created and maintained by other individuals and organisations.My film in 2020 - I went to Falmouth University and made a stop-motion film set to the story of my stepfather.In 2006 I asked him to make a recording and so I wanted to ask him about the war. When he made the recording, they were from when he was 14 from when he signed up to go in the army. It was nothing about fighting. It was really about him being a boy in North London in Harrow and daily life. 1940s and when the Blitz started.He tells about the bombing and how he was blown from the front of his house and a bomb dropped on the house opposite and it blew back. He came through the whole war without a scratch. He was part of the liberating troops who liberated Bergen Belsen. At the end of the war, he went on to Palestine and saw that the British army were tasked to look after the Jewish people who wanted to go there.Peter Reginald Conway. Two photos of him.
Short film - 'A New Life Tomorrow' - Vimeo.com/770292456
A New Life Tomorrow on Vimeo. This features his picture and his voice telling his story.He was in the early stages of Alzheimer’s, which means he repeated the stories which actually helped me. He recorded it on a Dictaphone and it had been put in a drawer and when he passed away in 2015 (he was 91) I just wanted to hear his voice. Everyone sat when I played the video because he had that sergeant major voice. He was a character!I felt it was really important that he was recorded.I think from what I've heard they were told to tell their troops not to share. Not to tell families. Because the families might find it upsetting. They had to do some terrible things. War is not nice. That's why a lot of soldiers didn't talk about it. To me, he told me quite a few things. One of the things he said - he arrived at D-Day and he never drank. His father was so proud that his father sent him cigarettes and a bottle of whisky. They had to go to Caen. This first battle he got blind drunk and said he cannot remember a thing about it!Why couldn't he remember? The whisky? Or it was so awful?
The Long Tale of Making Long Tail Geochemical Data FAIR, CARE and TRUST Compliant - Are We There Yet?
Creators: name: Wyborn, Lesley
Publisher: name: Zenodo
Year: 2024
Subjects: Semantics
Repositories
Identifiers
Engagement
Data
Workforce
Vocabularies
Governance
Strategy
Data Publishing

description: Geochemical data is typical of Long Tail communities and characterised globally by small-sized, highly variable datasets mainly collected by individuals or small research teams. Geochemistry emerged as a discipline in 1838 and has evolved from low throughput, manual analytical techniques to the highly computerised laboratories of today that rapidly produce highly diverse geochemical and isotopic datasets on samples down to the atomic scale. Exponential increases in data volumes are challenging long-established practices and capabilities for organising, analysing, preserving, and sharing data. Increasing applications of machine learning techniques to large geochemical data compilations highlight the enormous value of the curation and harmonisation efforts undertaken by domain-curated data systems, which provide easy access to large volumes of high-quality, well-organised and standardised data.

Unfortunately, geochemistry as a discipline has been slow to change its methods of storing, publishing and sharing geochemical data and only transitioned to electronic publication methods around 2000. Most researchers managed their data locally on C-drives or on departmental servers. Modern data management is now a necessity for the discipline to thrive in the age of digital data and artificial intelligence, particularly as journals and funders now require the formal publication of datasets in repositories.

It has been a long tale to transform the long tail geochemistry community into modern ways of storing, and curating data and making them compliant with the FAIR, CARE and TRUST principles. This paper will describe how this transition is taking place. Although focused on geochemistry, it is relevant to many other long tail communities.
Good neighbours matter: economic geography and the diffusion of human rights
Creators: name: T. Huw Edwards
name: Kernohan, David
name: Landman, Todd
name: Azizun Nessa
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Using multi-country panel data, this paper investigates the geopolitical and economic aspects of human rights performance. Human rights performance depends on the relative levels of economic development and spatial proximity to ‘good’ and ‘bad’ neighbours. The paper tests for basic effects of income, and applies spatial weighting models, to analyse the neighbours’ impact on human rights levels, treating this impact as partly endogenous. It takes into account size and distance when comparing each country’s human rights performance with what would be predicted from a weighted average of its neighbours’ performance. There are (1) geographical clusters and (2) size and proximity effects for human rights performance.
Axios/Ipsos Coronavirus Index Wave 62
Creators: name: Axios
Publisher: name: Roper Center for Public Opinion Research
Year: 2022

description: Changes in health in last week (2); activities in last week (7); changes in work and household over last few weeks (7); risk of different activities (6); safety procedures when leaving the house (3); concern about coronavirus (COVID-19) outbreak (1); risk of getting coronavirus (3); return to normal life (1); United States' management of coronavirus pandemic (2); trust in organizations/politicians to provide accurate information about coronavirus (4); behavior of other Americans having an impact on recovery from pandemic (1); coronavirus vaccine (10); government sending coronavirus supplies directly to individuals (2); public health mandates (3); personal response to coronavirus (1); coronavirus testing (12); main source of news (1).
Tinkering with the Past - Spatializing Historical Census Data in Australia
Creators: name: McEachern, Steven
name: Rigby, Michael
name: McDougall, Janet
name: Clough, Josh
Publisher: name: Zenodo
Year: 2019
Subjects: historical data
census
data access

description: The Australian population census is now over 100 years old. The capacity to access, analyze and visualize census data is however highly problematic for Australian researchers. Spatial analysis in particular is limited, with digital boundaries for the Australian census dating back only to 1981, despite the existence of census boundary maps dating back to the 1830s.

 The Australian Data Archive (ADA) and the Australian Urban Research Institute (AURIN) have been working to improve this access, as part of the Tinker project. With support from the Australian Research Data Commons and the 16 HASS-DEVL project partners, ADA and AURIN have been working to curate and link the tabular census data held at ADA with the spatial analysis environment operated by AURIN, enable access to census data prior to 1991 through the AURIN environment.

 This paper describes the project framework, the technical and administrative workflows established as part of the project to integrate ADA and AURIN systems, the census data resources now available, and next steps in the census support. The paper then concludes by outlining the potential for future project - a 250 year profile of the Australian population from colonization in 1770 to the present day.
A Unique Perspective on Animal Sacrifice (bali) from Acharya Sthaneshwar
Creators: name: Timalsina, Staneshwar
Publisher: name: Zenodo
Year: 2023
Subjects: Tantric philosophy
anava upaya
yantra
amnaya
Shiva
Shaiva
vimarsha-foundation
consciousness
mahadeva
Vasugupta
Sarvamnaya
tripura
Durga
Kaula
Abhinavagupta
Shiva Sutra
Kula
saivadvaita
vedanta
Mahakali
Tantra
Chandi
Kali
advaita vedanta
Bhairava
shambhava
timalsina
Spanda
Kashmir Shaivism
krama
Saundaryalahari
Tripura Rahasya
Tripurasundari
Camunda
agama
Devi Mahatmya
sarvamnaya
Guhyakālī
shakti
tantraloka
Divine Mother
sarvamnaya-oral-tradition-archive
trika
sthaneshwar timalsina
Īśāna
Mālinīvijayottaratantra
shakta upāya
Kubjika
Sadāśiva

description: Acharya Dr. Sthaneshwar Timalsina is an esteemed traditionally consecrated teacher of Shaiva-Shakta Hindu Tantra. He is also the Endowed Chair of Indic Studies in New York, U.S.A. at Stony Brook University's College of Arts & Sciences in the Department of Asian & Asian-American Studies. Acharya Sthaneshwar founded Vimarsha Foundation as a modern school (gurukula) for teaching and reflecting on the ancient wisdom of r̥ṣis and siddhas. Through Vimarsha Foundation, a non-profit organization, Acharya Sthaneshwar teaches shastra and sādhanā to students of all backgrounds. The Vimarsha Foundation hosts free semester length courses on classic texts of the Tantric Tradition and offers many more free video and written teachings. Visit our website to learn more: https://www.vimarshafoundation.org/

#hinduism #shaktism #tantra

Original YouTube video: https://www.youtube.com/watch?v=v4eJPW_VR0w

This presentation is part of the Sarvāmnāya Oral Tradition Archive.
Vimarsha Foundation. (2025). The Sarvāmnāya Oral Tradition Archive [Data set]. Zenodo. https://doi.org/10.5281/zenodo.15188107
Multi-wavelenth monitoring of the changing-look AGN NGC 2617 during state changes
Creators: name: Oknyansky, V. L.
name: Gaskell, C. M.
name: Huseynov, N. A.
name: Mikailov, Kh. M.
name: Lipunov, V. M.
name: Shatsky, N. I.
name: Tsygankov, S. S.
name: Gorbovskoy, E. S.
name: Tatarnikov, A. M.
name: Metlov, V. G.
name: Malanchev, K. L.
name: Brotherton, M. B.
name: Kasper, D.
name: Du, P.
name: Chen, X.
name: Burlak, M. A.
name: Buckley, D. A. H.
name: Rebolo, R.
name: Serra-Ricart, M.
name: Podesta, R.
name: Levato, H.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Optical and near-infrared photometry, optical spectroscopy, and soft X-ray and UV monitoring of the changing-look active galactic nucleus NGC 2617 show that it continues to have the appearance of a type-1 Seyfert galaxy. An optical light curve for 2010$-$2017 indicates that the change of type probably occurred between 2010 October and 2012 February and was not related to the brightening in 2013. In 2016 and 2017 NGC 2617 brightened again to a level of activity close to that in 2013 April. However, in 2017 from the end of the March to end of July 2017 it was in very low level and starting to change back to a Seyfert 1.8. We find variations in all passbands and in both the intensities and profiles of the broad Balmer lines. A new displaced emission peak has appeared in H$β$. X-ray variations are well correlated with UV$-$optical variability and possibly lead by $\sim$ 2$-$3 d. The $K$ band lags the $J$ band by about 21.5 $\pm$ 2.5 d and lags the combined $B + J$ bands by $\sim$ 25 d. $J$ lags $B$ by $\sim$ 3 d. This could be because $J$-band variability arises predominantly from the outer part of the accretion disc, while $K$-band variability is dominated by thermal re-emission by dust. We propose that spectral-type changes are a result of increasing central luminosity causing sublimation of the innermost dust in the hollow bi-conical outflow. We briefly discuss various other possible reasons that might explain the dramatic changes in NGC 2617.
description: 4 pages, 3 figures, accepted to the OAP
A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis
Creators: name: Rai, Rahul
name: Verma, Suresh K.
name: Kim, David
name: Ramirez, Veronica
name: Lux, Elizabeth
name: Chengjin Li
name: Sahoo, Susmita
name: Wilsbacher, Lisa D.
name: Vaughan, Douglas E.
name: Quaggin, Susan E.
name: Asish K. Ghosh
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: 60506 Virology

description: Hypertension-associated end-organ damage commonly leads to cardiac and renal fibrosis. As no effective anti-fibrotic therapy currently exists, the unchecked progression of fibrogenesis manifests as cardio-renal failure and early death. We have previously shown that FATp300—p300 with intrinsic factor acetyltransferase activity—is an essential epigenetic regulator of fibrogenesis, and is elevated in several fibrotic tissues. In this report, we investigate the therapeutic efficacy of a novel FATp300 inhibitor, L002, in a murine model of hypertensive cardio-renal fibrosis. Additionally, we examine the effects of L002 on cellular pro-fibrogenic processes and provide mechanistic insights into its antifibrogenic action. Utilizing cardiac fibroblasts, podocytes, and mesangial cells, we demonstrate that L002 blunts FATp300-mediated acetylation of specific histones. Further, incubating cells with L002 suppresses several pro-fibrogenic processes including cellular proliferation, migration, myofibroblast differentiation and collagen synthesis. Importantly, systemic administration of L002 in mice reduces hypertension-associated pathological hypertrophy, cardiac fibrosis and renal fibrosis. The anti-hypertrophic and anti-fibrotic effects of L002 were independent of blood pressure regulation. Our work solidifies the role of epigenetic regulator FATp300 in fibrogenesis and establishes it as a pharmacological target for reducing pathological matrix remodeling and associated pathologies. Additionally, we discover a new therapeutic role of L002, as it ameliorates hypertension-induced cardio-renal fibrosis and antagonizes pro-fibrogenic responses in fibroblasts, podocytes and mesangial cells.
Biotransformation of pungent constituents from ginger (Zingiber officinale Roscoe) by Colletotrichum gloeosporioides yields oxidative ortho–ortho coupling products
Creators: name: de Ávila, Roberta Marques Dias
name: Toffano, Leonardo
name: Fernandes, João Batista
name: da Silva, Maria Fátima das Graças Fernandes
name: de Sousa, Lorena Ramos Freitas
name: Vieira, Paulo Cezar
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Inorganic Chemistry

description: This work investigated the biotransformation of ginger constituents (zingerone, [6]-shogaol, [6]-gingerol, and methyl-[6]-gingerol) by the pathogenic fungus Colletotrichum gloeosporioides. Experiments were carried out with and without deuterium-labelled compounds. The product metabolites were analyzed by liquid chromatography coupled to tandem mass spectrometry and liquid chromatography solid phase extraction-nuclear magnetic resonance. Substrates supplied to the fungus were incorporated into metabolic pathways mostly by oxidation reactions, including aromatic carbon–carbon coupling. Zingerone and [6]-gingerol biotransformation products included biphenol dimers. A biodegradation pathway for biphenol formation was proposed based on the presence of the intermediate 4-(2-hydroxyethyl)-2-methoxyphenol, commonly identified from [6]-gingerol and [6]-shogaol biodegradation. This intermediate likely originates from a Baeyer–Villiger reaction followed by hydrolysis. The C–C coupling of molecules could result in phenolic oxidative ortho–ortho coupling, suggesting that biphenol dimers are products of C. gloeosporioides laccase catalysis.
Additional file 1 of LDL-cholesterol change and goal attainment following statin intensity titration among Asians in primary care: a retrospective cohort study
Creators: name: Fang, Hao Sen Andrew
name: Gao, Qiao
name: Lee, Mong Li
name: Hsu, Wynne
name: Tan, Ngiap Chuan
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Pharmacology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Percentage change of LDL-C with titrations in statin intensity (by gender).
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 816
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédéric
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 816, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 816, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Non-leptonic two-body weak decays of $Λ_c(2286)$
Creators: name: Geng, C. Q.
name: Hsiao, Y. K.
name: Lin, Yu-Heng
name: Liu, Liang-Liang
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We study the non-leptonic two-body weak decays of $Λ_c^+(2286)\to {\bf B}_n M$ with ${\bf B}_n$ ($M$) representing as the baryon (meson) states. Based on the $SU(3)$ flavor symmetry, we can describe most of the data reexamined by the BESIII Collaboration with higher precisions. However, our result of ${\cal B}(Λ_c^+ \to pπ^0)=(5.6\pm 1.5)\times 10^{-4}$ is larger than the current experimental limit of $3\times10^{-4}$ (90\% C.L.) by BESIII. In addition, we find that ${\cal B}(Λ_c^+ \to Σ^+ K^0)=(8.0\pm 1.6)\times 10^{-4}$, ${\cal B}(Λ_c^+ \to Σ^+ η^\prime)=(1.0^{+1.6}_{-0.8})\times 10^{-2}$, and ${\cal B}(Λ_c^+ \to p η^\prime)=(12.2^{+14.3}_{-\,\,\,8.7})\times 10^{-4}$, which are accessible to the BESIII experiments.
description: 12 pages, 1 figure, revised version accepted by PLB
Self-dual quasiperiodic systems with power-law hopping
Creators: name: Gopalakrishnan, Sarang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: We introduce and explore a family of self-dual models of single-particle motion in quasiperiodic potentials, with hopping amplitudes that fall off as a power law with exponent $p$. These models are generalizations of the familiar Aubry-Andre model. For large enough $p$, their static properties are similar to those of the Aubry-Andre model, although the low-frequency conductivity in the localized phase is sensitive to $p$. For $p \leq 2.1$ the Aubry-Andre localization transition splits into three transitions; two distinct intermediate regimes with both localized and delocalized states appear near the self-dual point of the Aubry-Andre model. In the intermediate regimes, the density of states is singular continuous in much of the spectrum, and is approximately self-similar: states form narrow energy bands, which are divided into yet narrower sub-bands; we find no clear sign of a mobility edge. When $p < 1$, localized states are not stable in random potentials; in the present model, however, tightly localized states are present for relatively large systems. We discuss the frequency-dependence and strong sample-to-sample fluctuations of the low-frequency optical conductivity, although a suitably generalized version of Mott's law is recovered when the power-law is slowly decaying. We present evidence that many of these features persist in models that are away from self-duality.
description: 12 pages, 20 figures; comments welcome
Regioselective synthesis of 6’’-O-lauroyl-1-kestose and 6’’’-O-lauroylnystose by sequential enzymatic reactions of transfructosylation and acylation
Creators: name: Campos-Valdez, Amador Roberto
name: Casas-Godoy, Leticia
name: Sandoval, Georgina
name: Hernández, Lázaro
name: Sassaki, Guilherme Lanzi
name: de Menezes, Leociley Rocha Alencar
name: Campos-Terán, José
name: Reyes-Duarte, Dolores
name: Arrizon, Javier
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Fructan fatty acid esters are amphiphilic compounds with potential applications in the food industry due to their surface-active properties on the air/water interface. In this work, the regioselective synthesis of fatty acid esters of short-chain inulin-type fructooligosaccharides (FOS) was carried out in a two-step process comprising sequential enzymatic reactions of transfructosylation and acylation. In the first step, Schedonorus arundinaceus sucrose:sucrose 1-fructosyltransferase (1-SST, EC 2.4.1.99) converted sucrose (600 g/L) into the trisaccharide 1-kestose and the tetrasaccharide nystose in a ratio 9:1 with their sum accounting for 53% (w/w) of total carbohydrates. In the second step, the FOS mixture was transesterified with vinyl laurate in 2-methyl-2-butanol by immobilized Candida antarctica lipase B (CALB) (EC.3.1.1.3). NMR analysis of the synthesized monolaurate FOS esters revealed a regioselective acylation of the 6-OH of the terminal fructosyl moiety of both 1-kestose and nystose. The hydrophilic-lipophilic balance (HLB) values of 6’’-O-lauroyl-1-kestose and 6’’’-O-lauroylnystose were 14.7 and 15.7, respectively; which suggests their use as oil in water (O/W) emulsifiers. The main compound 6’’-O-lauroyl-1-kestose with critical micelle concentration (CMC) of 0.6 mM and surface tension of 45.8 mN/m proved to be a more efficient surfactant than 6’’’-O-lauroylnystose (CMC 5.38 mM) and surface tension 36.26 mN/m). We report a regioselective method for the synthesis of lauryl-FOS using the abundant and renewable resource sucrose as the starting substrate.
title: 02_0815
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Performance comparison of commercial kits for isolating and detecting circulating tumor DNA
Creators: name: Wang, Mengyan
name: Huang, Xia
name: Li, Xin
name: Guo, Qiaomei
name: Xu, Wanxing
name: Zhao, Mingna
name: Wang, Xueqing
name: Wang, Lin
name: Lou, Jiatao
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Circulating tumor DNA (ctDNA), a fraction of cell-free DNA (cfDNA) in the circulatory system, is released from tumor cells and thus carries tumor-specific genetic signatures. Using blood-derived ctDNA to detect somatic mutations has shown great value in guiding cancer targeted therapy. Isolation and detection efficiencies are the key factors affecting the performance of ctDNA detection. To optimize and standardize our clinical practice, in this study, we analyzed the isolation efficiency of four commercial cfDNA purification kits: QIAamp circulating nucleic acid kit, AmoyDx® Circulating DNA kits, Microdiag® circulating DNA isolation kit, and MagMAX cell-free DNA isolation kit; and the detection efficiency of two mainstream domestic EGFR gene mutation detection kits: MicroDiag EGFR gene mutation detection kit and Fluorometric real-time PCR Detection Kit for the analysis of EGFR gene mutations. Reference materials and plasma samples collected from lung cancer patients and healthy volunteers were used for the analysis. Our results showed that QIAamp circulating nucleic acid kit and Microdiag® circulating DNA kit had the highest recovery rate (up to 21.25 ng/mL) for short DNA fragments of about 173 bp which is the peak length of ctDNA. For ctDNA detection, the MicroDiag® EGFR gene mutation detection kit showed the highest detection rate and sensitivity for detecting EGFR mutations at a mutant frequency of 0.5%. This work provides a reliable choice of commercial kits for the clinical application of ctDNA.
Using Literature Circle As Support Tool in Improving Literary Text Comprehension
Creators: name: Ramil Ilustre, Ph.D.
Publisher: name: figshare
Year: 2018
Subjects: subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: This is an action research focusing on the use of Literature Circles as a support tool for improving literary text comprehension.
Bertini Theorems for $F$-signature and Hilbert-Kunz multiplicity
Creators: name: Carvajal-Rojas, Javier
name: Schwede, Karl
name: Tucker, Kevin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics
subject: 14F18, 13A35, 14B05, 14J17

description: We show that Bertini theorems hold for $F$-signature and Hilbert--Kunz multiplicity. In particular, if $X \subseteq \mathbb{P}^n$ is normal and quasi-projective with $F$-signature greater than $λ$ (respectively the Hilbert--Kunz multiplicity is less than $λ$) at all points $x \in X$, then for a general hyperplane $H \subseteq \mathbb{P}^n$ the $F$-signature (respectively Hilbert--Kunz multiplicity) of $X \cap H$ is greater than $λ$ (respectively less than $λ$) at all points $x \in X \cap H$.
description: 23 pages, typos corrected and proofs improved, to appear in Math. Z
Performance comparison of commercial kits for isolating and detecting of circulating tumor DNA
Creators: name: Wang, Mengyan
name: Huang, Xia
name: Li, Xin
name: Guo, Qiaomei
name: Xu, Wanxing
name: Zhao, Mingna
name: Wang, Xueqing
name: Wang, Lin
name: Lou, Jiatao
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Circulating tumor DNA (ctDNA), a fraction of cell-free DNA (cfDNA) in the circulatory system, is released from tumor cells and thus carries tumor-specific genetic signatures. Using blood-derived ctDNA to detect somatic mutations has shown great value in guiding cancer targeted therapy. Isolation and detection efficiencies are the key factors affecting the performance of ctDNA detection. To optimize and standardize our clinical practice, in this study, we analyzed the isolation efficiency of four commercial cfDNA purification kits: QIAamp circulating nucleic acid kit, AmoyDx® Circulating DNA kits, Microdiag® circulating DNA isolation kit, and MagMAX cell-free DNA isolation kit; and the detection efficiency of two mainstream domestic EGFR gene mutation detection kits: MicroDiag EGFR gene mutation detection kit and Fluorometric real-time PCR Detection Kit for the analysis of EGFR gene mutations. Reference materials and plasma samples collected from lung cancer patients and healthy volunteers were used for the analysis. Our results showed that QIAamp circulating nucleic acid kit and Microdiag® circulating DNA kit had the highest recovery rate (up to 21.25 ng/mL) for short DNA fragments of about 173 bp which is the peak length of ctDNA. For ctDNA detection, the MicroDiag® EGFR gene mutation detection kit showed the highest detection rate and sensitivity for detecting EGFR mutations at a mutant frequency of 0.5%. This work provides a reliable choice of commercial kits for the clinical application of ctDNA.