title: ÐÑÐµÐ½ÐºÐ° ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð²ÑÐ¿Ð¸ÑÐºÐ¸ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð² Ñ ÑÑÑÑÐ¾Ð¼ Ð²ÑÐ²ÐµÐ´ÐµÐ½Ð¸Ñ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð¾Ð² Ð¸Ð· Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ð°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Evaluation of the criteria for the discharge of patients, taking into account the removal of radionuclides from the body
Creators: name: ÐÐ¾ÑÑÑÐ½Ð¾Ð²Ð°, ÐÐ¸ÐºÑÐ¾ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: Ð Ð°Ð´Ð¸Ð¾Ð»Ð¾Ð³Ð¸Ñ
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ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð²ÑÐ¿Ð¸ÑÐºÐ¸ Ð¿Ð¾ÑÐ»Ðµ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½Ð¾Ð¹ ÑÐµÑÐ°Ð¿Ð¸Ð¸

description: ÐÐ°Ð½Ð½Ð°Ñ Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¾ÑÐµÐ½ÐºÐµ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð²ÑÐ¿Ð¸ÑÐºÐ¸ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ¾Ð² Ð¿Ð¾ÑÐ»Ðµ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½Ð¾Ð¹ ÑÐµÑÐ°Ð¿Ð¸Ð¸ Ñ 227Th. Ð ÑÐ¾Ð´Ðµ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ»Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð´Ð¾Ð·Ð¸Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸, ÐºÐ¾ÑÐ¾ÑÑÐµ Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑ ÑÐ°ÑÑÑÐ¸ÑÐ°ÑÑ Ð¼Ð¾ÑÐ½Ð¾ÑÑÑ Ð¿Ð¾Ð³Ð»Ð¾ÑÐµÐ½Ð½Ð¾Ð¹ Ð´Ð¾Ð·Ñ Ð½Ð° Ð¼Ð¾Ð¼ÐµÐ½Ñ Ð²ÑÐ¿Ð¸ÑÐºÐ¸ D0 Ð¿ÑÐ¸ Ð²Ð²ÐµÐ´ÑÐ½Ð½Ð¾Ð¹ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ Ð½Ð° ÑÐ°ÑÑÑÐ¾ÑÐ½Ð¸Ð¸ Ð¾Ð´Ð½Ð¾Ð³Ð¾ Ð¼ÐµÑÑÐ° Ð¾Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ°. ÐÐµÑÐ²Ð°Ñ Ð¼Ð¾Ð´ÐµÐ»Ñ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑ ÑÐµÐ»Ð¾Ð²ÐµÐºÐ°, ÐºÐ°Ðº ÑÐ¾ÑÐµÑÐ½ÑÐ¹ Ð¸ÑÑÐ¾ÑÐ½Ð¸Ðº, Ð° Ð²ÑÐ¾ÑÐ°Ñ ÑÑÐ¸ÑÑÐ²Ð°ÐµÑ ÑÐ°ÑÐ¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ Ð¸Ð·Ð»ÑÑÐµÐ½Ð¸Ñ Ð¿Ð¾ Ð²ÑÐµÐ¼Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð¼Ñ. ÐÐ»Ñ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð¹ Ð·Ð½Ð°ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð¸Ñ ÐºÑÐ¸ÑÐµÑÐ¸ÐµÐ² Ð²ÑÐ¿Ð¸ÑÐºÐ¸ Ð±ÑÐ» Ð²ÑÐ±ÑÐ°Ð½ Ð¿ÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ð½ÑÐ¹ ÑÐ¾ÑÐ¸Ð¹-227. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ, ÐºÐ¾Ð½ÑÐµÑÐ²Ð°ÑÐ¸Ð²Ð½ÑÐ¹ ÑÐ°ÑÑÐµÑ, ÐºÐ¾ÑÐ¾ÑÑÐ¹ Ð¾Ð¿Ð¸ÑÐ°ÐµÑÑÑ Ð½Ð° Ð¿ÐµÑÐ²ÑÑ Ð´Ð¾Ð·Ð¸Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÑÑ Ð¼Ð¾Ð´ÐµÐ»Ñ, Ð½ÐµÑÐºÐ¾Ð»ÑÐºÐ¾ Ð·Ð°Ð²ÑÑÐ°ÐµÑ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½Ð¾Ðµ Ð·Ð½Ð°ÑÐµÐ½Ð¸Ðµ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ Ð´Ð¾Ð·Ñ Ð¾Ñ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÐ°, ÑÑÐ¾ Ð¿ÑÐ¸Ð²Ð¾Ð´Ð¸Ñ Ðº Ð²Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð´Ð¾Ð¿Ð¾Ð»Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÑ Ð¼ÐµÑ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸. ÐÑÐ¾Ð³Ð¾Ð¼ ÑÐ°Ð±Ð¾ÑÑ ÑÑÐ°Ð»Ð¾ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ðµ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½ÑÑ Ð´Ð»Ñ Ð»Ð¸Ñ Ð¸Ð· Ð½Ð°ÑÐµÐ»ÐµÐ½Ð¸Ñ ÑÑÐ¾Ð²Ð½Ð¸ Ð¼Ð¾ÑÐ½Ð¾ÑÑÐ¸ Ð´Ð¾Ð·Ñ Ð¸ Ð²Ð²Ð¾Ð´Ð¸Ð¼ÑÐµ Ð¿Ð°ÑÐ¸ÐµÐ½ÑÑ Ð°ÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸ 227Th Ð¿ÑÐ¸ ÑÐ°Ð´Ð¸Ð¾Ð½ÑÐºÐ»Ð¸Ð´Ð½Ð¾Ð¹ ÑÐµÑÐ°Ð¿Ð¸Ð¸.
description: This master's work is devoted to the assessment of the criteria for the discharge of patients after radionuclide therapy with 227Th. In the course of the work, dosimetric models were considered that allow calculating the absorbed dose rate at the time of discharge D0 with the injected activity at a distance of one meter from the patient. The first model considers a person as a point source, and the second takes into account the distribution of radiation throughout the body. For the practical significance of obtaining discharge criteria, promising thorium-227 was selected. As a result, the conservative calculation, which is based on the first dosimetric model, somewhat overestimates the obtained value of the dose rate from the patient, which leads to the introduction of additional safety measures. The result of the work was the determination of the dose rate levels that are safe for the population and the 227Th activity administered to the patient during radionuclide therapy.