cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Glyphosate epidemiology expert panel review: a weight of evidence systematic review of the relationship between glyphosate exposure and non-Hodgkin’s lymphoma or multiple myeloma
Creators: name: Acquavella, John
name: Garabrant, David
name: Marsh, Gary
name: Sorahan, Tom
name: Weed, Douglas L.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: We conducted a systematic review of the epidemiologic literature for glyphosate focusing on non-Hodgkin’s lymphoma (NHL) and multiple myeloma (MM) – two cancers that were the focus of a recent review by an International Agency for Research on Cancer Working Group. Our approach was consistent with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for systematic reviews. We evaluated each relevant study according to a priori criteria for study quality: adequacy of study size, likelihood of confounding, potential for other biases and adequacy of the statistical analyses. Our evaluation included seven unique studies for NHL and four for MM, all but one of which were case control studies for each cancer. For NHL, the case-control studies were all limited by the potential for recall bias and the lack of adequate multivariate adjustment for multiple pesticide and other farming exposures. Only the Agricultural Health (cohort) Study met our a priori quality standards and this study found no evidence of an association between glyphosate and NHL. For MM, the case control studies shared the same limitations as noted for the NHL case-control studies and, in aggregate, the data were too sparse to enable an informed causal judgment. Overall, our review did not find support in the epidemiologic literature for a causal association between glyphosate and NHL or MM.
Evaluation of Keto-Test in Urine and Milk for the Detection of Subclinical Ketosis in Periparturient Holstein Dairy Cattle
Creators: name: Osborne, Tera M.
name: Leslie, Ken E.
name: Duffield, Todd
name: Petersson, Christina S.
name: Ten Hag, Jeromy
name: Okada, Yoshihiro
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Subclinical ketosis causes significant economic loss to producer by decreasing milk production and increasing risk of periparturient disease. The dairy industry needs a cowside test to monitor periparturient dairy cattle for subclinical ketosis. The objective of this study was to determine the sensitivity, specificity and predictive values of the semi-qualitative Keto-Test in periparturient dairy cattle. This test was previously evaluated (Geishauser et al, J Dairy Sci, 2000) and shown to have a sensitivity and specificity of 80% and 76%, respectively, using a cut-point of 100 μmol/L betahydroxybutyrate (BHBA) or greater as a positive. However, in that evaluation tests were not performed prior to parturition or in the immediate periparturient period.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Intrinsic GTPase activity of a ribosomal maturation protein CgtA is associated with its inter-domain movement: insights from MD simulations and biochemical studies
Creators: name: Ananya Chatterjee
name: Partha P. Datta
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: CgtA is an essential ribosome associated GTPase protein of bacteria. It has three domains, viz., Obg, GTPase, and C-terminal domain. It is a multifunctional protein and it is being considered as a potential drug target against bacterial infections. Despite the importance, CgtA’s action mechanisms are not well known which warrants further study. Towards that goal, we are pursuing biochemical and computational studies in Vibrio cholerae CgtA (CgtAvc). Biochemically we found that a single amino acid substitution from Gly98 to Asp98 belonging to the Obg domain caused reduced GTPase activity of CgtAvc. The results from our comparative MD simulations studies revealed that in silico amino acid substitution for Gly98Asp influenced the inter-domain movement between Obg domain and GTPase domain. Moreover, we found significant alteration of intra-domain movements among the P-loop, G4 box, and G5 box of the GTPase domain, implying a potential cause for the reduced GTPase activity.
Effect of a Novel Salmonella Vaccine on Performance in a Large Expansion Dairy
Creators: name: Emery, Daryll
name: Straub, Darren
name: Slinden, Larry
name: Sandstrom, Jim
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: A novel subunit vaccine, consisting of a highly purified composition of Siderophore Receptor Proteins (SRPs) and Porins derived from Salmonella dublin and Salmonella typhimurium was administered to two groups of lactating cows in a large expansion dairy under controlled conditions.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Evaluation of Teat Cleanliness after Use of a Powered Mechanical Teat Scrubber
Creators: name: Johnson, A.
name: Rapnicki, P.
name: Stewart, S.
name: Godden, S.
name: Barka, Noah
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: This study compared teat cleanliness between two methods of udder preparation: a manual prep routine or a powered mechanical teat scrubber (CLIN-TEAT System, Westfalia, Surge Inc, Naperville, IL).
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Metabolic Predictors of Disease in Transition Dairy Cows
Creators: name: LeBlanc, Steven
name: Duffield, Todd
name: Leslie, Ken
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Risk factors for retained placenta (RP) and displaced abomasum (DA) are well described, but significant gaps remain in understanding their pathogenesis. This field study investigated metabolic tests available in clinical practice to identify cows at increased risk of RP and DA
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Novel Developments for Sustainable Hydropower
Creators: name: Rutschmann, Peter
name: Kampa, Eleftheria
name: Wolter, Christian
name: Albayrak, Ismail
name: David, Laurent
name: Stoltz, Ulli
name: Schletterer, Martin
Publisher: name: ETH Zurich
Year: 2022

description: ISBN:978-3-030-99138-8
description: ISBN:978-3-030-99137-1
Monitoring Lactating and Non-lactating Cow Udder Infection Dynamics Using Individual Cow Somatic Cell Counts
Creators: name: Cook, Nigel B.
name: Bennett, Tom B.
name: Emery, Kathy M.
name: Nordlund, Ken
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: It is clear that the non-lactating period is an extremely important time for occurrence of new intramammary infections, particularly with environmental pathogens. A low-cost method of monitoring this period, using somatic cell count (SCC) measurement immediately before and after the non-lactating period, would be very useful and would obviate the need for costly bacteriology.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Kōrero Kitea: Ngā hua o te whakamamatitanga: The impacts of digitised te reo archival collections
Creators: name: Crookston, Mark
name: Dr Gillian Oliver
name: Diamond, Paul
name: Tikao, Ariana
name: Dr ChernLi Liew
name: Sarsha-Leigh Douglas
Publisher: name: figshare
Year: 2016
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications
subject: 200321 Te Reo Maori (Maori Language)
subject: FOS: Languages and literature
subject: Digital Humanities

description: Kōrero Kitea is a research project that explores some of the ways digitised te reo Māori (Māori language) collections are being used, and what impacts that use is delivering to New Zealand – to the people and communities who use these digitised collections.
This paper reports on the first phase of the project, which gathered qualitative and quantitative information from an online survey conducted in April and May 2016.
Persistent Infection of Ovine Herpes virus Type 2 in a Dairy Herd
Creators: name: Callan, Robert J.
name: Van Metre, Dave C.
name: Powers, Jenny G.
name: Carbone, Cameo
name: Carman, Jane
name: Dinsmore, R. Page
name: Li, Hong
name: Collins, James K.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Malignant catarrhal fever (MCF) is a frequently fatal viral disease of cattle and other ruminants. Sheep-associated MCF is caused by ovine herpesvirus type 2 (OvHV-2). Over 95% of domestic sheep are asymptomatic carriers of OvHV-2 and serve as a source of infection for cattle. Previous studies demonstrated a significant high prevalence of asymptomatic OvHV-2 infection in adult dairy cattle from a herd housed in close proximity to sheep. While sheep are considered to be the primary source of infection in cattle, there are reports of MCF in cattle that are not in direct contact with sheep. The hypothesis for this study is that cattle infected with OvHV-2 can remain asymptomatic for extended periods of time and may transmit the virus to offspring through placenta and/or colostrum. The study's objectives were to monitor a group of adult cattle for evidence of OvHV-2 persistent infection and evaluate possible transmission of OvHV-2 to calves.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Social democratic austerity: the conditional role of agenda dynamics and issue ownership
Creators: name: Kraft, Jonas
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Over the past 30 years, left-wing parties have increasingly abandoned the interests of their core constituency to embark on a right-wing journey of fiscal austerity. I argue that the changing partisan pattern in fiscal policy can in part be explained by analysing social democrats’ need to signal fiscal competence. Drawing on issue ownership theory, my starting point is that voters perceive the Right as better able to balance the budgets than the Left. This leads left-wing incumbents to compensate for their bad fiscal reputation when concerns about balanced budgets are salient in the political system. They do so by reducing spending and budget deficits as much or even more than right-wing governments. In this way, an asymmetric fiscal reputation makes partisan differences in fiscal policy disappear. Support for my claims is found estimating a set of error correction models with data from 21 Organization for Economic Co-operation and Development countries between 1980 and 2006.
Antimicrobial Resistance of Campylobacter Isolated from Organic and Conventional Dairy Farms in the Midwestern and Northeastern United States
Creators: name: Halbert, L. W.
name: Kaneene, J. B.
name: Ruegg, P. L.
name: Warnick, L. D.
name: Wells, S. J.
name: Mansfield, L.
name: Green, A.
name: Geiger, A.
name: Fossler, C.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Campylobacter infections are the most commonly identified cause of human gastroenteritis in the United States. Increased resistance to several antimicrobials is being observed in Campylobacter from humans, swine, and poultry. Meanwhile, dairy cattle have been identified as sources of Campylobacter infection in humans through consumption of raw milk, educational visits to farms , or water contamination. Thus, dairy's role in dissemination of this foodborne pathogen warrants further study.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Effect of Tail Docking on Udder Hygiene and Milk Quality
Creators: name: Schreiner, D. A.
name: Ruegg, P. L.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Pre-milking udder hygiene can affect the rate of intramammary infection and bacterial numbers in milk. A study which monitored 413 dairy cows for two months to determine effects of tail docking on cow cleanliness and udder health reported no significant effect, but the study's ability to detect differences was low. This study looked at the specific effect of tail docking on somatic cell count (SCC), intramammary infection (MI) and udder and leg cleanliness in commercial dairy herds.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Abomasal and Duodenal Activity Alterations in Periparturient Dairy Cattle
Creators: name: Malone, Erin
name: Marti, Nathan
name: Madill, Scott
name: Fahning, Melvyn
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Abomasal dysfunction is theorized to underlie development of abomasal displacements. Abomasal function studies in healthy animals have not shown a conclusive role for diet, hypocalcemia, or neuroendocrine factors in altering abomasal motility. However, none of the studies were performed in the periparturient cow. The goal of this pilot project was to detect any significant alterations within the peripartum period in either antral or duodenal myoelectrical activity. We hypothesized healthy cows would not show significant alterations either during mid-lactation (as previously described) or between pre- and postpartum periods.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Behavioral and Physiologic Responses to Tail Docking in Calves and Preparturient Heifers
Creators: name: Schreiner, D. A.
name: Ruegg, P. L.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Many dairy farmers utilize tail docking because they believe it improves milking hygiene and increases the comfort of milking personnel. Few studies have been conducted to determine behavioral and physiological effects of tail docking in dairy cattle, and the optimal age to remove tails is unknown. Our study's objectives were to determine: 1) behavioral and hormonal effects of tail banding with rubber rings one month prior to first parturition in dairy heifers, both with and without use of an epidural and 2) to determine the behavioral response to tail banding using rubber rings on calves 1- 6 weeks of age.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Does Calfbood Infection with Cryptosporidium Impact Future Performance of Dairy Heifers?
Creators: name: Nydam, Daryl
name: Schaaf, Stephanie L.
name: Wade, Susan
name: Mohammed, Hussni
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Cryptosporidium is a zoonotic, parasitic protozoa that is of interest to livestock producers, veterinarians, and public health officials. It is the most prevalent pathogen isolated from diarrheic calves according to published reports. The financial impact of cryptosporidium on the performance of dairy herds is unknown. This study sought to determine whether calfhood cryptosporidiosis has an effect on future performance of dairy heifers.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Risk of Drinking-water Outbreaks of Cryptosporidiosis in Humans Caused by Cattle in Watersheds
Creators: name: Nydam, Daryl V.
name: Lindergard, Gabbi
name: Wade, Susan E.
name: Schaaf, Stephanie L.
name: Mohammed, Hussni O.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: There are at least two genotypes of Cryptosporidium paruum in nature-one that has only been isolated from humans (the H genotype) and one that has been isolated from a large range of mammals, including cattle and humans (the C genotype). By virtue of their presence in watersheds and the potential for water contamination with manure, cattle have often been implicated as a source of oocysts for human outbreaks of cryptosporidiosis. A recent review of drinking-water outbreaks in North America indicated that none in the United States and only one in British Columbia, Canada were associated with the C genotype. Thus, the objective of this study was to determine prevalence of C. paruum genotypes Hand C in dairy herds in the New York City Watershed (NYCW) and illustrate the risk posed by cattle to water-drinkers in this area.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Treatment for Bovine Respiratory Disease in U.S. Feedlots
Creators: name: Loneragan, Guy H.
name: Dargatz, David A.
name: Wagner, Bruce A.
name: Wineland, Nora E.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Bovine respiratory disease complex (BRD) is the leading cause of morbidity and mortality in U.S. feedlots. It is generally accepted that BRD results from an interaction of stressors, animal susceptibility and pathogens. Viral respiratory pathogens are believed to be primary invaders that allow bacterial colonization of the lower respiratory tract (LRT) which leads to bronchopneumonia. Prompt treatment of BRD-affected calves early in the course of disease with an appropriate antimicrobial appears to be the best strategy to effect a cure. Delayed or inappropriate treatment often leads to treatment failure, chronic disease, or death.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Herd Level Indicators for the Prediction of High-Risk Dairy Herds for Subclinical Ketosis
Creators: name: Duffield, Todd
name: Bagg, Randal
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: While several tests and surrogate measures have been developed for diagnosing subclinical ketosis at the individual cow level, herd-level indicators to predict which herds might benefit from increased surveillance and enhanced preventive practices could be extremely useful to veterinarians. This project investigated the usefulness of potential herd-level indicators for predicting high-risk herds for subclinical ketosis.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Effect of Dose of GnRH Used in the Ovsynch System on AI Pregnancy Rates in Beef Cows
Creators: name: Whittier, W. Dee
name: Hall, John B.
name: Britt, Amanda
name: Cline, Mark
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Estrous synchronization advances have the potential to dramatically increase the utilization of artificial insemination (AI) in beef cattle operations. Ultimately, the level of usefulness of these programs and AI in general will be the cost effectiveness of programs which are developed. Programs involving the use of GnRH and prostaglandins have been reported that allow for acceptable pregnancy rates using timed insemination and thus dramatically reducing handling, a significant deterrent to AI in beef cattle. One such scheme, Ovsynch, has utilized 100mg of GnRH for each of two injections in the scheme. Research conducted with dairy cattle has suggested that 50 mg GnRH provides similar pregnancy rate outcomes. Beef cow reproduction is significantly different than dairy reproduction due to different body composition, lactational demands and typical nutritional provision. If a lower dose of GnRH produces similar pregnancy outcomes, a significant economic advantage to the program would result. This trial was designed to compare the outcome of the four different combinations of 50 mg and 100 mg of GnRH in Ovsynch protocols.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
The Effect of Metaphylactic Antimicrobial Use on the Development of Antimicrobial Resistance in Fecal E. coli Isolates of Feedlot Cattle
Creators: name: Checkley, Sylvia
name: Chirino-Trejo, Manuel
name: Janzen, Eugene
name: Waldner, Cheryl
name: Campbell, John
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Much of the long-term economic and environmental stability of beef production seems to be driven by marketplace issues such as food safety and quality assurance that would include the potential presence of antimicrobial resistant bacteria. Long-acting injectable antimicrobials are widely used for metaphylaxis in calves on arrival at the feedlot. Previous feedlot trials by other researchers have associated metaphylaxis with lowered rates of morbidity and mortality from respiratory disease. Average daily gain, feed efficiency, case fatality rates, treatment rates, and relapse rates for bovine respiratory disease have also improved in animals where metaphylaxis is used. Metaphylaxis, therefore, has great industry significance from both an economic and animal welfare perspective. The objectives of this study were: 1) to determine the prevalence of fecal E. coli resistant to antimicrobials in auction-mart derived weaned calves, 2) to determine the effect of metaphylactic antimicrobial usage on the development of fecal E. coli resistant to various antimicrobials, and 3) to determine the persistence of antimicrobial resistant fecal E. coli and to evaluate the potential risk of their presence preslaughter.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Diagnostic Testing for Johne's Disease in the Cow-Calf Herd
Creators: name: Checkley, Sylvia
name: Waldner, Cheryl
name: Campbell, John
name: Appleyard, Greg
name: Clark, Edward
name: Janzen, Eugene
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Investigators collected fecal and tissue samples from 40 animals culled from a high prevalence Johne's herd. All of these samples were collected at the slaughterhouse and processed in the laboratory by a standardized technique. Culture of feces and histology of ileum, cecum, colon and mesenteric lymph nodes was performed by an experienced blinded pathologist. The prevalence of MAP for all tissues and agreement between tissue findings and culture of feces will be reported.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Evaluation of Alternate Year Vaccination Practices in a Cow-Calf Herd
Creators: name: Marsh, Todd
name: Chase, Chris
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Yearly vaccination of cow herds for reproductive diseases is the norm in US cattle industry. There has been controversy throughout veterinary medicine about vaccination of animals. Theoretically, a single dose of modified live vaccine has been claimed to give life-long immunity. Because there have not been multiple year duration studies in cattle, the long-term efficacy of cow vaccinations has been difficult to assess. In this study we divided a 1000-cow herd into three groups: 1) vaccination every year, 2) vaccination every other year, and 3) vaccination every third year. The herd production records and serology of the herd were subsequently evaluated.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Health and Performance Effects of Inadequate Colostral Transfer in Beef Calves
Creators: name: Dewell, R. D.
name: Hungerford, L. L.
name: Keen, J. E.
name: Hruska, Roman L.
name: Grotelueschen, D. M.
name: Rupp, G. P.
name: Griffin, D. D.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Study objectives were to evaluate associations between serum IgG 1 level, measured 24 to 48 hours after birth, and preweaning or feedlot morbidity, mortality, and average daily gain.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
A Longitudinal Study to Describe the Presence of Escherichia coli 0157:H7 and Salmonella spp in Feedlot Cattle Pens
Creators: name: Smith, D. R.
name: Moxley, R. A.
name: Hinkley, S.
name: Klopfenstein, T. J.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: The objective of this study was to use a novel diagnostic strategy to describe the presence of Escherichia coli O157:H7 and Salmonella spp in pens of feedlot cattle over the course of the feeding period.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Leptin
Creators: name: Baker, Jerome
name: Brown, Dan T.
name: Pence, Mel
name: Vann, Rhonda
name: Keisler, Duane H.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Lutenizing hormone production and pulse frequency are the keys to initiating puberty in heifers. Thus, leptin appears to be a key element in partitioning of energy resources in direct response to energy availability. Energy partitioning in the bovine allocates available energy first to body maintenance, and as more energy becomes available, to growth, then to lactation and lastly to reproduction. Fat reserves accumulate as energy becomes abundant. The production of leptin by adipocytes affects leptin concentration at the neuro-receptor site level, and that determines how energy resources are partitioned. If this concept is accurate, then a threshold level of leptin, greater than that required to maintain body homeostasis and provide for growth, must be available to initiate the onset of puberty in beef heifers.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Retrospective ideological representation and its impact on democratic satisfaction*
Creators: name: Ferland, Benjamin
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Congruence between government policies and citizen preferences is a key element that increases the quality of democracy. While scholars have shown that governments generally adopt ideological positions and propose policies close to citizen preferences, they have neglected to consider whether citizens respond to promises or to actual enactments. The paper addresses this gap in two ways. First, we propose a new measure that captures how close a citizen is on average to the policies enacted by the incumbent government, namely retrospective ideological representation – the ideological distance between the position of a respondent and the incumbent government at the end of its term in office. We show that this measure captures retrospective information associated with governments’ actions and in particular whether the government increases or decreases social spending during its mandate period. Second, we show that retrospective ideological representation has a substantial impact on citizens’ democratic satisfaction and greater than prospective ideological representation – an established measure of congruence – which is the ideological distance between the positions of a respondent and the elected government after an election.
Principles of Bovine Pharmacology
Creators: name: Wagner, Sarah
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Certain considerations must be taken into account whenever one decides to administer a drug to a food animal. Some issues are relevant to drug use in any species, while others are specific for drug use in food animals. General principles of drug use in food animals are discussed, including withholding time, appropriateness of drug choice, and the potential for adverse effects. Some specific drug classes and compounds are discussed in order to provide examples of the factors that go into therapeutic decision-making.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Possible Ribose Synthesis in Carbonaceous Planetesimals
Creators: name: Paschek, Klaus
name: Kohler, Kai
name: Pearce, Ben K. D.
name: Lange, Kevin
name: Henning, Thomas K.
name: Trapp, Oliver
name: Pudritz, Ralph E.
name: Semenov, Dmitry A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The origin of life might be sparked by the polymerization of the first RNA molecules in Darwinian ponds during wet-dry cycles. The key life-building block ribose was found in carbonaceous chondrites. Its exogenous delivery onto the Hadean Earth could be a crucial step toward the emergence of the RNA world. Here, we investigate the formation of ribose through a simplified version of the formose reaction inside carbonaceous chondrite parent bodies. Following up on our previous studies regarding nucleobases with the same coupled physico-chemical model, we calculate the abundance of ribose within planetesimals of different sizes and heating histories. We perform laboratory experiments using catalysts present in carbonaceous chondrites to infer the yield of ribose among all pentoses (5Cs) forming during the formose reaction. These laboratory yields are used to tune our theoretical model that can only predict the total abundance of 5Cs. We found that the calculated abundances of ribose were similar to the ones measured in carbonaceous chondrites. We discuss the possibilities of chemical decomposition and preservation of ribose and derived constraints on time and location in planetesimals. In conclusion, the aqueous formose reaction might produce most of the ribose in carbonaceous chondrites. Together with our previous studies on nucleobases, we found that life-building blocks of the RNA world could be synthesized inside parent bodies and later delivered onto the early Earth.
description: Published in Life, 24 pages, 8 figures (all colored)
Regulations Concerning Food Animal Drug Use
Creators: name: Apley, Mike
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: As a Veterinary Technician, you are involved daily in the practice of administering medications to animals. These administrations may be done according to the label directions, or the treatment regimen may be altered from the label. This altered use is referred to as extralabel, or off-label use. The Animal Medicinal Drug Use Clarification Act (AMDUCA) has moved extralabel drug use in veterinary medicine from an approach of "illegal but tolerated if you do it this way" to "legal if you follow specific guidelines". This paper presents portions of the AMDUCA regulations as published in the Federal Register. These sections have been selected to highlight key areas of the regulations and should not be treated as the full text of the regulations. Directions for obtaining the full text of appropriate documents are included below. In addition, anyone working with dairy animals should be aware of the Pasteurized Milk Ordinance (PMO) regulations and their state regulations regarding drugs on dairies.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation
Creators: name: Ali, Shabana Kouser
name: P. Sneha
name: J. Priyadharshini Christy
name: Zayed, Hatem
name: C. George Priya Doss
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Mutations in the fibrinogen gamma chain (FGG) gene have been associated with various disorders, such as dysfibrinogenemia, thrombophilia, and hypofibrinogenemia. A literature survey showed that a residue exchange in fibrinogen Milano I from γ Asp to Val at position 330 impairs fibrin polymerization. The D356V (D330V) mutation located in the C-terminus was predicted to be highly deleterious and to affect the function of the protein. The pathogenicity of the altered gene and changes in protein functions were predicted using in silico methods, such as SIFT, PolyPhen 2, I-Mutant 3.0, Align GV–GD, PhD–SNP, and SNPs&GO. The secondary structure of the mutant protein was unwound by the end of the 50-ns simulation period, and a structural change in the helix-turn transition of the alpha-helical (352–356) region residues was observed. Moreover, a change in the length of the helical region was visualized in the mutant trajectory file, indicating the local transient unfolding of the protein. The obtained computational results suggest that the substitution of the neutral amino acid valine for the acidic amino acid aspartic acid at position 356 results in an unwound conformation within 50 ns, which might contribute to defective polymerization. Our analysis also provides insights into the effect of the conformational change in the D356V (D330V) mutant on protein structure and function.
Antimicrobial Peptides and Surfactant Proteins
Creators: name: Ackerman, Mark R.
name: Brogden, Kim A.
name: McCray, P. B.
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: Although some vaccines and antibiotics have been very effective in preventing and treating respiratory disease, they have not been fully satisfactory. Recently, components of the innate immune system have been increasingly appreciated for their role in host defense against microbial pathogens. These molecules include lysozyme and lactoferrin, but recent work in cattle, sheep, man and other species have identified new classes of peptides expressed by respiratory epithelial cells that have potent microcidal activity in nanogram quantities. These peptides, termed antimicrobial peptides (AMP), include defensins, cathelicidins and anionic peptides. Some are expressed continuously whereas expression of others is stimulated by infection/inflammation. In calves, we have found that two AMP from the defensin family, tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP), are expressed in the newborn and increased in response to Mannheimia (Pasteurella) haemolytica infection. In contrast, sheep beta defensin-1 (SBD-1) is not induced by infection and, in fact, appears decreased during viral infection with paramyxovirus-3 (PI-3). Decreased SBD-1 by Pl-3 may increase the lung's susceptibility to secondary infections or re-infections. Other innate defense molecules include proteins released with lung surfactant. Surfactant protein A and D (SAD) can opsonize and aggregate respiratory syncytial virus (RSV) and activate alveolar macrophages. Preliminary work suggests that chronic bacterial infections result in reduced SpA and SpD expression and we are currently assessing SAD expression in response to Pl-3 and RSV. A long-term goal of our work is to identify ways to up-regulate expression of AMP and/or surfactant proteins in the neonate and at times of stress in older animals in order to reduce microbial colonization. Other investigators are seeking ways to utilize AMP's as a new class of antibiotics.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Immobilienwirtschaft aktuell 2022: Beiträge zur immobilienwirtschaftlichen Forschung
Creators: name: CUREM - Center for Urban & Real Estate Management
Publisher: name: ETH Zurich
Year: 2022
Subjects: Immobilieninvestment
Immobilienmanagement
Projektentwicklung
Urban Management
Wohneigentum
Mietpreismodelle
Schulhäuser
Innenverdichtung

description: Dieser Band enthält zehn aktuelle Beiträge zur Schweizer Immobilienwirtschaft. Die Arbeiten bieten raschen und einfachen Zugriff auf aktuelle Erkenntnisse aus den Themengebieten "Immobilieninvestment", "Immobilienmanagement", "Projektentwicklung" sowie "Urban Management". 

Die Publikation Immobilienwirtschaft aktuell erscheint jährlich und wird vom Center for Urban & Real Estate Management (CUREM) herausgegeben. Sie enthält die Zusammenfassungen der besten Abschlussarbeiten des Masters of Advanced Studies in Real Estate. Ziel ist die Förderung der akademischen und zugleich praxisnahen Diskussion immobilienrelevanter Themen in der Schweiz. Die vollständigen Abschlussarbeiten stehen auf www.curem.uzh.ch zum kostenlosen Download zur Verfügung. 

CUREM ist Teil der Wirtschaftswissenschaftlichen Fakultät an der Universität Zürich und widmet sich der immobilienwirtschaftlichen Forschung und Weiterbildung. Ziel ist die Förderung einer professionellen Immobilienwirtschaft in der Schweiz. Nebst dem RICS akkreditierten, berufsbegleitenden Studiengang zum "Master of Advanced Studies in Real Estate" und dem "Certificate of Advanced Studies in Urban Management" führt CUREM verschiedene Kompaktkurse, Expertenworkshops und Fachveranstaltungen durch.
description: Immobilienwirtschaft aktuell
description: ISBN:978-3-7281-4135-4
description: ISBN:978-3-7281-4134-7
In situ complexation of rhodium(II) tetracarboxylates with some derivatives of cysteine and related ligands studied by 1H and 13C nuclear magnetic resonance spectroscopy
Creators: name: Rafał Głaszczka
name: Jarosław Jaźwiński
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: The complexation of N-phthaloyl, N-formyl, and N,N-dimethyl derivatives of S-methylcysteine methyl ester (both racemic and optically pure) with three dimeric rhodium(II) salts, acetate Rh2AcO4, trifluoroacetate Rh2TFA4, and (R)-(+)-α-methoxy-α-trifluoromethylphenylacetate Rh2Mosh4 was investigated by nuclear magnetic resonance spectroscopy (NMR) at room and lower temperatures. The complexation was carried out in situ, in CDCl3 solution using titration procedure; the results were examined by the analysis of 1H and 13C NMR chemical shift change (Δδ). The complexation of free S-methyl cysteine and hydrochloride salt of its methyl ester was performed in D2O solution. For comparison, complexation of some derivatives of leucine, phenylalanine, and proline was examined. N-phthaloyl and N-formyl derivatives of cysteine formed 1 : 1 and 1 : 2 axial complexes with all dirhodium salts. Rhodium substrates were bonded via sulfur. In one case, the complexation of Rh2TFA4 by both sulfur and N-formyl oxygen was noted. Similar complexation of Rh2TFA4, via CHO group, was found for N-formyl derivatives of leucine, phenylalanine, and proline. For N,N-dimethyl derivative of cysteine, both N and S atoms were involved in bonding. At room temperature, in all cases, ligand exchange was fast on the NMR timescale.
title: 03_0456
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
BGA Guidelines
Creators: name: Griffin, Dee
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: National Cattlemen's Beef Association's (NCBA) and state cattlemen's association BQA Program is designed for our industry, and all cattlemen ... the cattlemen are in charge! The program began in 1980 and has grown to include 47 states. Nebraska began its third revitalization of the BQA program in February of 1997. The development and coordination of the revitalization program has been through the Nebraska Cattlemen, Nebraska Beef Council, Nebraska Veterinary Medical Association and University of Nebraska Cooperative Extension. Other states have started revitalization programs similar to the BQA program.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Increasing Your Practice's Output and Better Serving your Clients Utilizing a Veterinarian/Technician Team Approach
Creators: name: Day, John D.
name: Kral, Jannell
Publisher: name: American Association of Bovine Practitioners  Proceedings of the Annual Conference
Year: 2002

description: It is a common desire of many veterinarians practicing in animal agriculture to be able to add to the bottom line of the livestock operation that they work for by consulting with the producer in ways to improve management of their operation, commonly called production medicine. Yet many practitioners who have stated a desire to provide additional production medicine services to clients are not successful in implementing these services, partly due to a lack of time. One avenue to create the time necessary to provide extra services is the utilization of the veterinarian/technician team approach. Along with improving the beef quality of producer's career-change dairy cattle, this approach has increased the efficiency of the veterinary services provided, which saves the livestock operation money. Ultimately it allows for more services to be provided by the veterinarian/technician team, such as developing standard operating procedures and treatment protocols, implementing and monitoring programs, conducting field trials, and a myriad of other services. The ability to increase a practice's output and better serve clients increases the veterinarian and technician job satisfaction and increases the client's satisfaction with the practice and the total return to their operation.
description: American Association of Bovine Practitioners Proceedings of the Annual Conference, 2002
Role of E542 and E545 missense mutations of PIK3CA in breast cancer: a comparative computational approach
Creators: name: D. Thirumal Kumar
name: C. George Priya Doss
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Recent statistics describe breast cancer as the leading cause of death among women across the world with varied causes and reasons. Lifestyle, diet, genetic and environmental factors introduce their generous contributions towards breast cancer, among which genetic factors have lately become one of the most important aspects in understanding the mechanism. Although various genes have already been reported in causing breast cancer, PIK3CA stands second on the list. Mutations observed in this gene have the ability to trigger the different activities of the cell, thereby bypassing the regular cellular cycle. Among the mutations in PIK3CA, three hotspot mutations were commonly reported, one in the catalytic domain (position HIS1047) and other two in the helical domain (position GLU542 and GLU545). In the helical domain of PIK3CA, the lysine substitution at 542–545 positions was significantly studied in causing breast cancer. To compare the deleterious effect of these mutations, in silico prediction tools along with molecular dynamics simulations and molecular docking approach was initiated to analyse the change in binding landscape upon mutation. In this comparative analysis, we report that the mere existence of mutant E545K can trigger the function of the protein but may not be as harmful as H1047R. Among the two mutations E542K and E545K, the latter shows the most deleterious effect that correlates with the previous reported experimental studies. We assume the results observed in this combinatorial computational study might further pave a better way for providing better treatment procedures.