cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 3: of Clinical and virological factors associated with gastrointestinal symptoms in patients with acute respiratory infection: a two-year prospective study in general practice medicine
Creators: name: Minodier, Laetitia
name: Masse, Shirley
name: Capai, Lisandru
name: Blanchon, Thierry
name: Pierre-Emmanuel Ceccaldi
name: Werf, Sylvie Van Der
name: Hanslik, Thomas
name: Charrel, Remi
name: Falchi, Alessandra
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases
subject: 60506 Virology
subject: FOS: Biological sciences

description: a) Seasonal distribution of influenza viruses identified in patients consulting for an Acute Respiratory Infection (ARI) during 2014-2015 season and 2015-2016 season. (PDF 389Â kb)
Tobacco industry influence on the video game industry
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Research demonstrates that viewing smoking scenes in movies is causally related to smoking initiation among adolescents and that the tobacco industry has played a key role in assuring that tobacco imagery is present in movies that appeal to adolescents and young adults. Less is known about the relationship between viewing smoking imagery in video games and smoking initiation; however, recent research demonstrates that tobacco imagery, including tobacco brands, is present in a substantial subset of games played by adolescents. Players and game designers agree that insertion of tobacco content allows messages to be rapidly conveyed about characters, including such tobacco-industry tropes as “coolness” and “rebelliousness.” Our preliminary analysis of internal tobacco industry documents suggests that tobacco companies have long understood the potential for video games to serve as promotional vehicles for their products among youth, and have cultivated relationships with video game makers. This project will fully explore these relationships, including examining tobacco company payments to video game makers and video arcade trade groups, and tobacco industry involvement in promoting the use of cigarette imagery and logos in video games. It will develop knowledge essential for creating policies to counter tobacco industry influence on the video game industry.

 Specific aim: Retrieve and analyze tobacco industry documents in order to describe the relationship between the tobacco industry and the video game industry. Ours will be the first study to address the relationship between the tobacco industry and the video game industry. As such, it will provide valuable knowledge that can be used to inform policies to minimize the use of video games as promotional vehicles for tobacco products.
Physopleurus rafaeli Santos-Silva 2006
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Physopleurus
Physopleurus rafaeli

description: 48. Physopleurus rafaeli Santos-Silva, 2006b: 266, figs. 1, 2
Holotype, male
Type locality. Brazil, Amazonas: Manaus (Estrada ZF –2, km 14, torre 3,02°35'21"S, 60°06'55"W), 10– 13.XII.2004, C.S. Motta, A.S. Filho, S. Trovisco & M. Cutrin
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 353, DOI: 10.5281/zenodo.250291
In-utero smoke exposure and epigenetic activation of GFI1-family oncogenes
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Medulloblastoma is the most common brain cancer in children, with fewer than 65% of patients surviving to adulthood. Although survival has improved in recent decades with more targeted and aggressive therapy, disease prevention remains the ultimate goal of pediatric cancer research. In order to prevent medulloblastoma occurrence, we must first identify modifiable causes of the disease. One cause of medulloblastoma is increased activity of a gene called GFI1. We recently demonstrated that in-utero exposure to tobacco smoke causes changes in this gene among newborn children, potentially leading to its activation. This suggests that eliminating tobacco smoke exposure in pregnant women could help to reduce the occurrence of this aggressive childhood brain cancer. Although this is exciting early evidence, we need to perform a more detailed investigation in a larger population of children, both with and without medulloblastoma, to make firmer conclusions Our lab has access to blood specimens, taken at birth, from approximately one thousand children who went on to develop medulloblastoma. We also have newborn blood specimens from thousands of healthy children with which to make comparisons. We propose to investigate specific changes to the DNA of 260 children who developed medulloblastoma and 466 cancer-free children in order to determine if smoking-associated DNA changes are more common in the children who developed brain cancer. We believe that the proposed study will have a meaningful and lasting impact on tobacco-related disease research due to its value in three key areas. First, the project has the potential to identify a modifiable cause of childhood brain cancer, potentially helping us to prevent future occurrences. Second, successfully linking specific DNA changes associated with in-utero smoke exposure to future cancer development in children will open the door to many future studies of diverse tobacco-associated pediatric illnesses. Finally, linking maternal smoking during pregnancy to risk of cancer in her children could help motivate young women to give up tobacco products for the sake of their child’s health.
Halgerda wasinensis Eliot 1904
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Halgerda
Halgerda wasinensis

description: Halgerda cf. wasinensis Eliot, 1904
(Figure 16 J)
Material examined. Nine specimens. MB28-005076, POA, 10 May 2014, 41m, 29mm; MB28-005077, POA, 0 8 May 2014, 41m, 19mm; MB28-005078, POA, 0 8 May 2014, 41m, 29mm. MB28-005079, POA, 0 8 May 2014, 41m, 18mm; MB28-005080, 5 spcs., POA, 10May 2014, 40m, 16–45mm.
Habitats. Subtropical rocky reefs bellow 40m.
Occurrences. Ponta do Ouro.
Geographic distribution. Western Indian Ocean. Mozambique.
Remarks. This morphotype differs from the other H. wasiniensis morphotypes by the presence of a midline on the dorsum rather than the typical network, as well as by large dark spots under the mantle. Moreover, they are found only bellow 38m and on a particular reef in the extreme south of Mozambique. No clear internal differences could be found between this morphotype and the other H. wasinensis and our prelimary molecular analyses do not clearly distinguish these morphotypes. Thus, until additional molecular analyses are completed we cannot know if this morphotype is a variation of H. wasinensis or a recently diverged species.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 49, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Coleoxestia anthracina Martins & Monne 2005
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Coleoxestia
Coleoxestia anthracina

description: 1. Coleoxestia anthracina Martins & Monné, 2005: 143, figs. 247, 248 Holotype, male
Type locality. Brazil, Pará: Serra Norte (Manganês), 24.X.1984, R.B. Neto
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 359, DOI: 10.5281/zenodo.250291
Oncogenic reprogramming of protein translation by DDX3 inactivation
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Cancer is often caused by changes to the DNA sequence of genes. These changes cause cells to grow uncontrollably, producing a tumor. Different tumors within the same cancer type can be caused by different DNA changes. It is important to understand how the DNA changes in cells lead to cancer formation, because treatments may work for individuals with some DNA changes but not others. This project aims to understand how DNA changes in the brain tumor medulloblastoma lead to cancer formation by modeling cancer in the lab.

 The focus of this project is on changes to a gene called DDX3, which is altered in half of patients with specific types of medulloblastoma. DDX3 is a protein machine that changes the shape of RNA molecules in cells, leading to changes in which proteins are produced. The changes to DDX3 break the protein so it can no longer perform its normal function. This means that drugs that inhibit the activity of DDX3 are not likely to help medulloblastoma patients. However, if we knew how breaking the activity of DDX3 changed the production of other proteins in cells, we would have a better idea of other drugs to try for patients with DDX3 changes.

 A new technology has emerged in the last five years called CRISPR–Cas9, which allows researchers to make precise changes to DNA in cells. We will use this technology to introduce changes identical to those found in medulloblastoma patients into cells. We will then use techniques we developed to measure how changes to DDX3 affect production of other proteins in cells. We will also perform experiments to understand why some RNA molecules require DDX3 activity while others do not. Together, these experiments will explain how changes to DDX3 can promote cancer formation.

 We anticipate the results of this research will impact cancer patients in multiple ways. First, a better understanding of how DDX3 changes lead to cancer, we may propose new targets for drugs. Second, there may be FDA-approved drugs that target proteins that are affected by changes to DDX3 that patients could take. Third, patients within the same cancer type sometimes respond differently to treatments, and understanding the effects of DDX3 changes may explain this. Lastly, there are children with brain disorders involving similar changes to DDX3 but without other DNA changes that are found in medulloblastoma, and our research will predict whether these patients are likely to develop cancer. In summary, our proposed cancer research program will impact the development of medulloblastoma treatments, patient therapeutic strategies, and individuals with other DDX3-related disorders.
Halgerda Bergh 1880
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Halgerda

description: Halgerda sp. 1
(Figure 16 K)
Material examined. Two specimens. MB28-004661, ZD, 26 Mar. 2013, 32m, 16mm. MB28-004721, ZT, 11 Aug. 2013, 42m, 42mm.
Habitats. Subtropical rocky reefs.
Occurrences. Zavora.
Geographic distribution. Western Indian Ocean. South Africa (Coleman 2008) and Mozambique.
Remarks. This species is similar to H. maricola (Fahey & Gosliner 2001) from Western Australia; it differs externally by the presence of much larger spots between the ridges and linned as opposed to spotted gills. Debelius and Kuiter (2007, pg. 235) illustrate a photograph of a Halgerda from western Australia which is externally more similar to this species than to the description of H. maricola, nevertheless without further examination of such a specimen is not possible to confirm its identity.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on pages 49-50, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Comprehensive Program to Reduce Tobacco-Related Health Disparities in CHCs
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Smoking prevalence among adults living in poverty remains too high. Community health centers (CHCs) can play a pivotal role in addressing smoking in this population. Yet, lack of clinic protocols, trained staff, and robust electronic support systems can make the delivery of smoking cessation services challenging. Smoking cessation activities in CHCs also often fail to address social barriers to successful quit attempts (e.g. housing instability, social isolation, stress, mental illness, co-occurring substance use) or behaviors (e.g. poor diet, physical inactivity) that can magnify cardiovascular disease and cancer risks from smoking. With NIH funding, we developed “Connection to Health” (CTH), a comprehensive program for diabetes patients in CHCs, designed to assess social and behavioral determinants of health and to facilitate self-management support with automated motivational text messages, community referrals, and follow-up. Our CHC partners and stakeholders have requested to use CTH as the foundation for a new type of smoking cessation program. We will pursue two aims in this study: 1) to adapt CTH to incorporate smoking cessation services in English and Spanish with input from providers and patients; and 2) to test CTH with 90 smokers in three CHCs within our practice-based research network, comparing outcomes to a standard smoking cessation program for 90 additional smokers. This pilot will inform a future grant proposal focused on smoking in CHCs, where thousands of California’s medically vulnerable tobacco users receive care.
Coleoxestia tupunhuna Martins & Monne 2005
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Coleoxestia
Coleoxestia tupunhuna

description: 2. Coleoxestia tupunhuna Martins & Monné, 2005: 140, fig. 246 Holotype, male
Type locality. Brazil, Pará: Serra Norte (Caldeirão), 29.X.1984
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 359, DOI: 10.5281/zenodo.250291
Halgerda Bergh 1880
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Halgerda

description: Halgerda sp. 2
(Figure 16 L)
Material examined. Eight specimens. MB28-004417, ZRP, 0 5 May 2011, 1 m, 15mm (preserved); MB28-004565, ZRP, 0 7 Jun. 2012, 2m, 9mm; MB28-0 0 4679, ZRP, 25 May 2013, 1 m, 20mm; MB28-004731, ZRP, 22 Aug. 2013, 2m, 27mm; MHN-YT903, ZRP, 0 7 Sep. 2013, 0.5m, 30mm; MB28-004807, ZRP, 17 Mar. 2014, 0.5m, 42mm; MB28-004901, NKA, 10 Jun. 2014, 18m, 27mm; ZMBN94225, PAE, 2 Feb. 2014, 20– 25m, 20mm.
Habitats. Subtropical tidal reefs, rocky reefs and topical coral reefs.
Occurrences. Ponta do Ouro, Zavora, Paindane, Nacala, Nuarro and Pemba.
Geographic distribution. Indian Ocean. British Indian Ocean Territory, Maldives (Yonow et al. 2002), Kenya (Rudman 1978), Madagascar (Eliot 1905), Tanzania (Gosliner et al. 2008) and Mozambique (Gosliner et al. 2008; King and Fraser 2014).
Remarks. This species has been thought to be an Indian Ocean variation of Halgerda tessellata (Bergh, 1880). However, it differs genetically and anatomically. The principle of the external difference is the absence of the submarginal band formed by white spots present in the Pacific specimens.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 50, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain
Creators: name: Gatica, Damián
name: Damasio, Alejandro
name: Pascual, Clarence
name: J. Klionsky, Daniel
name: Ragusa, Michael J.
name: Popelka, Hana
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine

description: Macroautophagy/autophagy is a conserved catabolic recycling pathway involving the sequestration of cytoplasmic components within double-membrane vesicles termed autophagosomes. The autophagy-related (Atg) protein Atg13 is a key member of the autophagy initiation complex. The Atg13 C terminus is an intrinsically disordered region (IDR) harboring a binding site for the vacuolar membrane protein Vac8. Recent reports suggest Atg13 acts as a hub to assemble the initiation complex, and also participates in membrane recognition. Here we show that the Atg13 C terminus directly binds to lipid membranes via electrostatic interactions between positively charged residues in Atg13 and negatively charged phospholipids as well as a hydrophobic insertion of a Phe residue. We identified 2 sets of residues in the Atg13 IDR that affect its phospholipid-binding properties; these residues overlap with the Vac8-binding domain of Atg13. Our data indicate that Atg13 binding to phospholipids and Vac8 is mutually exclusive, and both are required for efficient autophagy. Abbreviations: Atg: autophagy-related; CD: circular dichroism; Cvt: cytoplasm-to-vacuole targeting; IDR: intrinsically disordered region; ITC: isothermal calorimetry; MIM: MIT-interacting motif; MKO: multiple-knockout; PAS: phagophore assembly site; PC: phosphatidylcholine; PS: phosphatidylserine; PtdIns: phosphatidylinositol; PtdIns3P: phosphatidylinositol-3-phosphate
Baeocera barda Löbl, 2015, sp. nov.
Creators: name: Löbl, Ivan
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Staphylinidae
Baeocera
Baeocera barda

description: Baeocera barda sp. nov.
Figs 9-13
Holotype: MHNG; ♂; Indonesia, Lombok Pusuk Pass 300 m 3.XI.1991, I. Löbl degr. forest leaf litter.
Paratypes: MHNG; 1 ♀; with the same data as the holotype. – MHNG; 1 ♂; Lombok Bangko-Bangko (SW Lombok), 50 m degr. monsoonal for. D. Agosti 19.3.1991. – SMNS; 1 ♂; Lombok Is. Senaro, N slope of Rinjani, 2-5.Feb 1994 Bolm lgt. 1100 m.
Etymology: The species epithet is a Latin adjective meaning slow.
Description: Length 1.45-1.58 mm, width 0.87- 1.05 mm. Colour and most external characters as in B. badia. Length/width ratio of antennomeres as follows: III 17/7: IV 22/7: V 30/7: VI 26/8: VII 33/12: VIII 23/9: IX 30/13: X 28/15: XI 34/19. Mesepimera about 2.5 times as long as wide and 1.5 time as long as interval to mesocoxae. Punctation on lateral parts of metaventrite coarser than in B. badia. Submesocoxal lines strongly arcuate, submesocoxal areas about as long as half of interval to metacoxae. Metanepisterna not narrowed posteriad, suture straight, with variably large punctures. Sternite 1 impunctate in middle, basal puncture row interrupted between coxae.
Male: Protarsomeres hardly widened. Aedeagus (Figs 9-12) 0.37-0.43 mm long, fairly sclerotized. Median lobe similar to that in B. badia, articular process almost indistinct. Parameres long, slightly widened to mid-length and slightly sinuate in dorsal view, bent in basal third and slightly widened in apical third in lateral view. Internal sac with almost evenly thick, curved and proximally tuberculate sclerite, basal membranous denticles well visible but distinct lobe absent.
Female: Ovipositor (Fig. 13) with long distal gonocoxite slightly narrowed apically, bearing two long apical and four short subapical setae, gonostyle present, with one long apical seta.
Distribution: Indonesia: Lombok.
Type locality: Lombok, Pusuk Pass 300 m.
Comments: This species is very similar to and obviously closely related with B. badia. It may be reliably distinguished by its aedeagal characters, i.e., by the shape of the parameres and sclerotized piece of the internal sac. It differs from B. badia also by the impunctate centre of the sternite 1 and shorter apical antennomeres.
description: Published as part of Löbl, Ivan, 2015, On the Scaphidiinae (Coleoptera: Staphylinidae) of the Lesser Sunda Islands, pp. 75-120 in Revue suisse de Zoologie 122 (1) on page 79, DOI: 10.5281/zenodo.14582
Neoclytus turuna Galileo & Martins 2007
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Neoclytus
Neoclytus turuna

description: 3. Neoclytus turuna Galileo & Martins, 2007: 349, fig. 5 Holotype, female
Type locality. Brazil, Pará: Serra Norte (No.1, Campo), 14.VIII.1984, M.S. Torres Current name. Rostroclytus turuna (Galileo & Martins, 2007)
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 359, DOI: 10.5281/zenodo.250291
Toxicants and Cardiovascular Effects: Cannabis vs Tobacco
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Legal sale of cannabis to adults for recreational use in California began on January 1, 2018. Despite favorable public perceptions, and widespread and increasing prevalence of use, the health consequences of cannabis use in its various forms are not fully understood. We will be conducting a clinical study to examine toxicant exposure and short-term cardiovascular effects of smoked and vaped cannabis (dry herb) in comparison to tobacco cigarettes. We are comparing cardiovascular disease risks of cannabis to tobacco cigarettes because tobacco cigarette smoking is a major risk factor for cardiovascular diseases.

 In our study, dual cannabis-tobacco smokers will cross over between smoking cannabis, vaping cannabis with PAX dry herb vaporizer, and their usual brand of tobacco cigarettes. Each product will be studied on two consecutive inpatient days at a hospital research ward on different weeks. On the first day, participants will use the assigned product in a standardized session followed by 6 hours of abstinence, during which we collect blood samples, then 2 hours of ad libitum use. We will compared pharmacokinetic, subjective, and physiologic effects. On the second day, participants will use the product as desired during the day. Exposure to toxicants will be measured in 24-hour urine; heart rate and blood pressure will be monitored continuously for 24 hours; and, subjective effects will be measured. Finally, cardiovascular measures and toxicant biomarkers will be assessed on a day of enforced abstinence on the research ward.

 The study is timely, given the growing public health concern of cannabis use and expected increasing intensity of use with recreational legalization. The expected findings of the study will help us better understand the potential contributions of cannabis use to cardiovascular disease.
Additional file 1: Appendix A. of Evidence for current recommendations concerning the management of foot health for people with chronic long-term conditions: a systematic review
Creators: name: Edwards, Katherine
name: Borthwick, Alan
name: McCulloch, Louise
name: Redmond, Anthony
name: Pinedo-Villanueva, Rafael
name: Prieto-Alhambra, Daniel
name: Judge, Andrew
name: Arden, Nigel
name: Bowen, Catherine
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Electronic search strategy: an example using Embase. (DOCX 84 kb)
Halgerda Bergh 1880
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Halgerda

description: Halgerda sp. 3
(Figure 17 A)
Material examined. Four specimens. MB28-005031, 3 spcs., POB, 26 Dec. 2014, 40– 50mm, 15m, collected by Jenny Strömvoll; MB28-005032, PO, 3 Dec. 2014, 40mm, 17m, collected by Jenny Strömvoll. Habitats. Subtropical rocky reefs.
Occurrences. Ponta do Ouro.
Geographic distribution. Western Indian Ocean. Réunion (Bidgrain 2006b) and Mozambique. Remarks. This species belong to the Halgerda willey Eliot, 1904 complex but appears undescribed.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 50, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Pantomallus piruatinga Martins 1997
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Pantomallus
Pantomallus piruatinga

description: 4. Pantomallus piruatinga Martins, 1997: 76, fig. 1 Holotype, female
Type locality. Brazil, Pará: km 90 da rodovia Belém–Brasília, 28.VII.1972, P. Waldir
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 359, DOI: 10.5281/zenodo.250291
Births, Deaths Under One Year and Infant Mortality Rates in New Jersey by Color 1921-1930, Statistics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart shows the number of biths to African Americans versus the number of births to white Americans for each year beginning in 1921 and ending in 1930. Then it shows the number of deaths of babies less than one year of age and the death rate per 1,000 births in both racial groups. The information for this chart has been adapted from the Division of Vital Statistics of the United States Bureau of the Census.
Halgerda Bergh 1880
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Halgerda

description: Halgerda sp. 4
(Figure 17 B)
Material examined. Six specimens. MB28-004459, ZWH, 0 5 Feb. 2012, 17m, 25mm, collected by L. Robisson; MB28-004527, ZGWS, 23 Mar. 2012, 22m, 25mm; MHN-YT567, ZA51, 23 Aug. 2012, 12m, 24mm; MB28- 0 0 4698, ZGWS, 26 Jul. 213, 18m, 29mm; MB28-004716, ZT, 11 Aug. 2013, 33m, 20mm; MB28-0 0 4802, ZY, 0 4 Feb. 2014, 33m, 24mm.
Habitats. Subtropical rocky reefs.
Occuurences: Zavora.
Geographic distribution. Western Indian Ocean. Mozambique.
Remarks. This species resemble H. toliara but differs externally by the lack of secondary lines between the ridges and small tubercles surround the mantle.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 50, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
White and Colored Death Rates From Tuberculosis in Certain Cities of New Jersey-- 1928-1930, Statistics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart indicates the average number of deaths and rate of death from tuberculosis within the African American community versus the white community of Trenton, Camden, Elizabeth, East Orange, Atlantic City, Perth Amboy, Montclair, Orange, New Brunswick, and Plainfield. The information for this chart was taken from Supplement to Statistical Handbook of the New Jersry Tuberculosis League.
HER3-biased Sec61 modulators for treatment of cancers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Tobacco usage is the largest risk factor for head and neck squamous cell carcinomas (HNSCCs). Smokers diagnosed with HNSCC exhibit reduced overall survival relative to non-smokers. Moreover, HNSCC patients who are current tobacco users are at a higher risk of disease recurrence compared to patients that have never used tobacco. Several studies indicate that the cell-surface receptor HER3, a member of the human epidermal growth factor receptor family, plays an essential role in HNSCC. HER3 expression is correlated with worse overall survival in HNSCC patients. HER3 has also been linked to other types of cancer such as breast, ovarian, colon, and EGFR-driven lung cancers.

 Therapeutic antibodies that target the extracellular portion of HER3 have produced disappointing results in clinical trials, possibly due to the resistance caused by the growth factor-independent HER3 signaling. Thus, novel therapeutic approaches are needed to completely block HER3 functions. We believe that drugs that can eliminate HER3 protein expression will show superior efficacy compared to function-blocking antibodies. Recently, we have developed novel small molecules that inhibit HER3 biosynthesis, resulting in the elimination of HER3 from cancer cells. In this project, I propose to develop novel chemistry approaches to identify HER3 modulators with greater potency and selectivity. These compounds will be tested in preclinical models of HNSCC.
Additional file 4: of Clinical and virological factors associated with gastrointestinal symptoms in patients with acute respiratory infection: a two-year prospective study in general practice medicine
Creators: name: Minodier, Laetitia
name: Masse, Shirley
name: Capai, Lisandru
name: Blanchon, Thierry
name: Pierre-Emmanuel Ceccaldi
name: Werf, Sylvie Van Der
name: Hanslik, Thomas
name: Charrel, Remi
name: Falchi, Alessandra
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: List of information collected by General Practitioners in the Case Report Form during consultation recruiting of patients with ARI. (DOCX 20Â kb)
Death Rates for Certain Diseases in New Jersey by Color 1921-1930, Statistics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart demonstrates the rate of death of African Americans from tuberculosis, pneumonia, heart disease, cancer, homicide, and other causes compared to the death rate of whites by the same causes. In all catagories, except for cancer, the death rate of the African Americans is significantly higher than the death rate of the whites by the same causes. This chart was adapted from the Division of Vital Statistics of the United States Bureau of the Census.
Changes in the Employment of Workers--Manufacturing and Mechanical Industries By Color: New Jersey 1910-1930, Statistics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart indicates the percent changes in employment in the manufacturing and mechanical industries by sex and race from 1910 to 1930.
Modelagem da propagação do fogo no cerrado brasileiro: uma abordagem híbrida com autômatos celulares e algoritmos evolutivos
Creators: name: Fernandes Arantes, Augusto
name: Araújo Lima, Danielli
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 410205
subject: Fire ecology

description: Os incêndios florestais são um fator significante no cerrado brasileiro, com afrequência de ocorrências desse tipo aumentando cada vez mais devido àinterferência humana com o bioma. A modelagem destes incêndios é essencialpara o entendimento, prevenção e combate de fenômenos futuros,possibilitando o desenvolvimento de estratégias fundamentadas e testadas emambientes simulados. Abordagens tradicionais de simulação frequentementesofrem em capturar as inúmeras e complexas interações entre vegetação,topografia e condições climáticas, dada a enorme quantidade de variáveis emuma simulação deste tipo. Para isso, propomos a construção de um modelohíbrido, que utiliza de um autômato celular (AC) para a representaçãogeográfica de uma região e da propagação do fogo dentro dela, juntamente aum algoritmo genético, que ajusta os inúmeros parâmetros do AC,automaticamente criando simulações cada vez mais próximas de um dadocaso real. Para a calibragem do algoritmo evolutivo, diversas técnicas ehiperparâmetros foram testados e avaliados quanto às suas eficácias, bemdiferentes durações dos experimentos e estudo das taxas de aprendizado.Visando uma simulação mais próxima da realidade possível, imagens desatélite de incêndios reais foram selecionadas, tratadas, e posteriormenteusadas pelo nosso modelo evolutivo, que foi capaz de atingir um alto grau desimilaridade com estes dados de referência. A avaliação do modelo foi feita emmúltiplos níveis, desde uma análise qualitativa das simulações alcançadas,bem como a repetição de 100 experimentos para a coleta de dados estatísticosdo modelo. Dados os experimentos realizados, foi possível observar umdesempenho positivo, tanto quando em escala individual, quanto dacoletividade dos experimentos, evidenciando que, apesar da naturezaestocástica do autômato celular e do algoritmo genético, a convergência dosparâmetros ao longo de todos experimentos seguiu uma mesma linha,demonstrando uma robustez do método e a reprodutibilidade do mesmo.Trabalhos futuros podem ser desenvolvidos buscando a expansão do modelo,tanto na adição de novos parâmetros ao AC, como relevo, intensidade dachama ou interações com áreas urbanas, quanto na sofisticação do AG e suaadaptabilidade a diferentes cenários e ambiente, sendo necessária a coleta dedados e imagens reais para a realização dos experimentos.
Halgerda Bergh 1880
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Halgerda

description: Halgerda sp. 5
(Figure 17 C)
Material examined. One specimen. MB28-004933, ZSC, 0 8 May 2014, 16m, 31mm. Habitats. Subtropical rocky reefs.
Occurrences. Zavora.
Geographic distribution. Western Indian Ocean. Mozambique. Remarks. This species is externally similar to H. wasinensis, but lacks yellow margins on the rhinophoral sheaths.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 52, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Negros of New Jersey in Manufacturing and Mechanical Industries 1930,1920,1910; Statistics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart shows the growth of the number of African Americans in manufacturing and mechanical positions from 1910 to 1930. The number more than doubles from 1910 to 1920 and then continues to drastically increase up through 1930.
Negros in Professional Service (Both Sexes) New Jersey 1930, Statistics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart shows the number of African Americans in particular professions next to the number of people in the professions overall in New Jersey in 1930. The professional positions include lawyer, chemist, reporter, artist, and librarian. The numbers are very low in relation to the size of the African American population.
Nyssicostylus overali Galileo & Martins 1990
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Nyssicostylus
Nyssicostylus overali

description: 5. Nyssicostylus overali Galileo & Martins, 1990b: 12, fig. 1 (Figure 17) Holotype, female
Type locality. Brazil, Pará: Serra Norte (Manganês), 17.IX.1985, F.F. Ramos
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 359, DOI: 10.5281/zenodo.250291
Economic Impact of Proposition 56 on Low-Income Californians
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: On November 8, 2016, California voters passed Proposition 56, increasing cigarette taxes by $2.00 per pack effective April 1, 2017. This tax increase will reduce the affordability of cigarettes especially for economically disadvantaged smokers and is expected to reduce cigarette smoking. Low-income people smoke at higher rates than high-income people. In 2013-2014, 15.7% of California adults who live under the Federal Poverty Level (FPL) were current smokers, while 9.4% of those who live above 300% FPL smoked. If low-income smokers are more responsive to the tax increase in quitting or reducing cigarette consumption, Proposition 56 may lead to reduced disparities in cigarette smoking and the resulting health burden for low-income Californians. The objective of this study is to evaluate the economic impact of the cigarette tax increase from Proposition 56 on low-income Californians by analyzing four specific aims.

 Aim 1. Estimate the responsiveness of smoking prevalence, smoking intensity, and total cigarette consumption to cigarette price increases among low-income Californians. We hypothesize that low-income Californians are more price-responsive than high-income Californians.

 Aim 2. Evaluate the impact of Proposition 56 on smoking prevalence, the proportions of current smokers who are light, moderate and heavy smokers, and cessation rates among low-income Californians; and assess whether these impacts differ from those for high-income Californians.

 Aim 3. Estimate the impact of Proposition 56 on healthcare cost attributable to cigarette smoking and the amount paid by MediCal and Medicare for low-income Californians.

 Aim 4. Examine whether low-income smokers minimize the price effect from Proposition 56 by using coupons or purchasing cheaper cigarettes from other states or via the internet, and compare the financial burden of cigarette spending before and after the implementation of Proposition 56.

 Findings from this study will provide useful information on whether Proposition 56 will narrow the gap in smoking prevalence between low- and high-income Californians, whether it will save MediCal cost, and how much financial burden it will impose on low-income smokers in California. California has long been a leader in tobacco control and our experience with this major tobacco tax policy will help inform other state’s tobacco control policymakers.
Sebadoris nubilosa
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Nudibranchia
Discodorididae
Sebadoris
Sebadoris nubilosa

description: Sebadoris nubilosa (Pease, 1871)
(Figure 17 D–E)
Material examined. Two specimens. MB28-004888, NHR, 0 5 Jun. 2016, 5m, 180mm; MHN-YT1377, NKA, 16 Jun. 2014, 15m, 112mm.
Habitats. Tropical coral reefs.
Occurrences. Nacala and Nuarro.
Geographic distribution. Indo-west, central Pacific. Hawaii (Gosliner et al. 2008), Marianas (Pease 1871), Fiji (Brodie & Brodie 1990), Australia, Maldives, Red Sea, Réunion Island, Tanzania (Gosliner et al. 2008) and Mozambique.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 52, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Negro Tradespeople in New Jersey By Occupation 1910,1920 and 1930, Statics from The Negro Wage Earner of New Jersey.
Creators: name: Hall, Egerton Elliott
Publisher: name: No Publisher Supplied
Year: 1935

description: This is a chart from a study done by Dr. Egerton Elliot Hall of the unequal distribution of employment across races, particularly concerning African Americans and white Americans throughout the 1910s through the early 1930s within New Jersey. During this time many African American migrants from Southern states were moving to the New Jersey area. Through this study Hall explores the effects of the unequal distribution of employment on various aspects of the lives of African Americans such as their health and education. This particular chart indicates the number of African Americans working in certain trades in 1910, 1920, and 1930. These number grew steadily from one decade to the next. The source for this chart was the Occupation Statistics of the United States Bureau of the Census.