cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary Figures and Tables from The rapid in vivo evolution of Pseudomonas aeruginosa in ventilator-associated pneumonia patients leads to attenuated virulence
Creators: name: Wang, Ke
name: Chen, Yi-qiang
name: Salido, May M.
name: Kohli, Gurjeet S.
name: Kong, Jin-liang
name: Liang, Hong-jie
name: Yao, Zi-ting
name: Xie, Yan-tong
name: Wu, Hua-yu
name: Cai, Shuang-qi
name: Drautz-Moses, Daniela I.
name: E. Darling, Aaron
name: C. Schuster, Stephan
name: Yang, Liang
name: Ding, Yichen
Publisher: name: The Royal Society
Year: 2017

description: Pseudomonas aeruginosa is an opportunistic pathogen that causes severe airway infections in humans. These infections are usually difficult to treat and associated with high mortality rate. While colonizing the human airways, P. aeruginosa could accumulate genetic mutations that often lead to its better adaptability to the host environment. Understanding these evolutionary traits may provide important clues for the development of effective therapies to treat P. aeruginosa infections. In this study, 25 P. aeruginosa isolates were longitudinally sampled from the airways of four ventilator-associated pneumonia (VAP) patients. Pacbio and Illumina sequencing were used to analyse the in vivo evolutionary trajectories of these isolates. Our analysis showed that positive selection dominantly shaped P. aeruginosa genomes during VAP infections and led to three convergent evolution events, including loss-of-function mutations of lasR and mpl, and a pyoverdine-deficient phenotype. Specifically, lasR encodes one of the major transcriptional regulators in quorum sensing, whereas mpl encodes an enzyme responsible for recycling cell wall peptidoglycan. We also found that P. aeruginosa isolated at late stages of VAP infections produce less elastase and are less virulent in vivo than their earlier isolated counterparts, suggesting the short-term in vivo evolution of P. aeruginosa leads to attenuated virulence.
Data Table of Cattle Bone Measurements (Table 2) [Structured Data from Open Context]
Creators: name: Elizabeth Wright
name: Margherita Schäfer
name: Barbara Stopp
name: Elisabeth Marti-Grädel
name: Francesca Ginella
name: Manar Kerdy
name: Miki Bopp-Ito
name: Sabine Deschler-Erb
name: Jörg Schibler
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data Table of Cattle Bone Measurements (Table 2) Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 166-data-table-of-cattle-bone-measurements-table-2.csv contains the tabular data content for this resource in a CSV format.
JSON: The 166-data-table-of-cattle-bone-measurements-table-2.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
Immunogenicity, antibody persistence, and safety of the 60 μg hepatitis B vaccine in hemodialysis patients: a multicenter, randomized, double-blind, parallel-controlled trial
Creators: name: Feng, Yongliang
name: Shi, Xiaohong
name: Shi, Jing
name: Gao, Linying
name: Liu, Guangming
name: Cheng, Yanpeng
name: Pan, Minghu
name: Li, Chunxia
name: Wang, Jun
name: Guo, Xuxia
name: Zhang, Yawei
name: Liang, Xiaofeng
name: Wang, Suping
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Background: To evaluate the immunogenicity, antibody persistence, and safety of the 60 µg hepatitis B vaccine in hemodialysis patients in China. Methods: We conducted a multicenter, randomized, double-blind, parallel-controlled trial including 352 hemodialysis patients who were centrally randomized in a ratio of 1:1 to receive a 20 µg (IM20 group) or 60 µg (IM60 group) recombinant hepatitis B vaccine at months 0, 1, and 6. Results: The vaccine-elicited antibody responses peaked at month 7, and declined at month 12. At month 7, the IM60 group had stronger GMC of anti-HBs, and a higher proportion of seroconversion and high-level response than the IM20 group did (P < 0.05). Better immune responses were observed in the IM60 group, especially for those aged or in the high-frequency hemodialysis population. Conclusion: The high dose 60 µg recombinant hepatitis B vaccines elicited stronger immune responses than the 20 µg hepatitis B vaccine did among hemodialysis patients. Clinical trial registration: ClinicalTrials.gov, number NCT02963714.
High-Performance Nanocatalyst for Adsorptive and Photoassisted Fenton-Like Degradation of Phenol: Modeling Using Artificial Neural Networks
Creators: name: Dr Mustafa Gazi
name: Dr Akeem Adeyemi Oladipo
name: Ojoro, Zainab Eniola
name: Professor Hayrettin Ozan Gulcan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: High-performance activated carbon-zinc oxide (Ac–ZnO) nanocatalyst was fabricated via microwave-assisted technique. Ac–ZnO was characterised and the results indicated that Ac–ZnO is stable, had a band gap of 3.26 eV, the surface area of 603.5 m2g−1, exhibited excellent adsorptive and degrading potentials. About 93% phenol was adsorbed within 550 min of reaction by Ac–ZnO. Impressively, a complete degradation was achieved in 90 min via a photo–Fenton/Ac–ZnO system under optimum conditions. An artificial neural network (ANN) model was developed and applied to study the relative significance of input variables affecting the degradation of phenol in a photo-Fenton process. The ANN results indicate that increases in both H2O2 and Ac–ZnO dosage enhanced the rate of phenol degradation. The highest rate constant at the optimum conditions was 0.093 min−1 and found to be consistent with the ANN predicted rate constant (0.095 min−1).
An Interview with Anna Dominiczak .docx
Creators: name: Anderson, Hilary
Publisher: name: figshare
Year: 2017
Subjects: subject: 110399 Clinical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: I interviewed Professor Dame Anna Dominiczak, head of college of Medical, Veterinary and Life Sciences at the University of Glasgow. We discussed the future of the college, the EU referendum and women in STEM.
\\https://www.uofgcce.org/single-post/2016/04/12/An-Interview-with-Anna-Dominiczak
title: La chouette et Suleyman
title: The owl and Suleyman
titleType: AlternativeTitle
Creators: name: Vanhove, Martine
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Bedja
subject: bej
subject: anthropological_linguistics
subject: linguistique
subject: conte

description: légende / conte hagiographique sur le défi de la chouette à Dieu à l'époque du prophète Suleyman
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
title: Le joueur
title: The gambler
titleType: AlternativeTitle
Creators: name: Vanhove, Martine
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Bedja
subject: bej
subject: anthropological_linguistics
subject: linguistique
subject: conte
subject: humour

description: conte humoristique édifiant sur les mésaventures d'un joueur
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
An Interview with Dr Jennifer Paxton.docx
Creators: name: Anderson, Hilary
Publisher: name: figshare
Year: 2017
Subjects: Anatomy

description: An Interview with Dr Jennifer Paxton, an anatomical perspective on tissue engineering.
https://www.uofgcce.org/single-post/2016/06/14/An-Interview-with-Dr-Jennifer-Paxton
title: Test particle - plasma interactions
Creators: name: Gibson, Alasdair L.
Publisher: name: University of Glasgow
Year: 1973
Subjects: subject: Pure sciences, two-dimensional plasmas.

description: This thesis describes investigations into the properties of a two-dimensional plasma carried out by theory and computer simulation. The predictions of previous work concerning the wake generated by a suprathermal test particle in a two-dimensional plasma have been verified within the very noticeable constraints of the computer simulation model. Other work has been done, which has lent itself better to a good description by simulation. Primarily, in the electrostatic case, the slowing of a test particle in a two-dimensional collisionless plasma has been adequately quantitatively demonstrated. In the case of two-dimensional magnetised plasma, expressions for the potential due to a test charge have been derived. It is shown that the nature of the potential distribution round the test particle, and a fortiori, the shielding properties of the plasma have been radically altered by the inclusion of the magnetic field. Whatever tractable means were available have been used to indicate the form of the potential distributions for both stationary and moving test particles.
title: Kilit 'Oor
title: Kilit 'Oor
titleType: AlternativeTitle
Creators: name: Vanhove, Martine
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Bedja
subject: bej
subject: anthropological_linguistics
subject: linguistique
subject: humour

description: blague à propos d'un glouton
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Palladium catalyzed Heck reaction of 2-iodoanilines under ligand-free conditions in air
Creators: name: Chen, Xia
name: Zhou, Xiao-Yu
name: Wang, Liang-Guang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biochemistry
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Palladium catalyzed Heck reaction of 2-iodoanilines and acrylate has been developed. The palladium catalyzed Heck reaction of 2-iodoanilines can readily occur in CH3CN using Pd(OAc)2 (5.0 mol%) as catalyst, NEt3 as base under ligand-free conditions. And 2-alkenylanilines were obtained as the cross-coupling products with medium to high yield.
Palladium catalyzed heck reaction of 2-iodoanilines under ligand-free conditions in air
Creators: name: Chen, Xia
name: Zhou, Xiao-Yu
name: Wang, Liang-Guang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Biochemistry
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: Palladium catalyzed Heck reaction of 2-iodoanilines and acrylate has been developed. The palladium catalyzed Heck reaction of 2-iodoanilines can readily occur in CH3CN using Pd(OAc)2 (5.0 mol%) as catalyst, NEt3 as base under ligand-free conditions. And 2-alkenylanilines were obtained as the cross-coupling products with medium to high yield.
Determination of the stability constant of cobalt-substituted mono-lacunary Keggin-type polyoxometalate and its electrocatalytic water oxidation performance
Creators: name: Li, Jiansheng
name: Wang, Jidan
name: Zhang, Liuyang
name: Sang, Xiaojing
name: You, Wansheng
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: The anion form of a cobalt-substituted mono-lacunary Keggin-type polyoxometalate (POM) complex in aqueous solution was identified as [Co(H2O)(H3PW11O39)]2− and its stability constant was determined to be 5.19 × 104 by spectrophotometry. Additionally, the electrocatalytic performances toward water oxidation of different concentrations of [Co(H2O)(H3PW11O39)]2− were investigated in the neutral phosphate buffer solution, and it was found that [Co(H2O)(H3PW11O39)]2− anion itself has little activity; the activity of [Co(H2O)(H3PW11O39)]2− solution actually results from dissociated [Co(H2O)6]2+. This work provides a simple way to understand the origin of catalytic water oxidation activity of a POM-based complex.
Determination of the stability constant of cobalt substituted mono-lacunary Keggin type polyoxometalate and its electrocatalytic water oxidation performance
Creators: name: Li, Jiansheng
name: Wang, Jidan
name: Zhang, Liuyang
name: Sang, Xiaojing
name: You, Wansheng
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: The anion form of a cobalt substituted mono-lacunary Keggin type polyoxometalate (POM) complex in aqueous solution was identified as [Co(H2O)(H3PW11O39)]2− and its stability constant was determined to be 5.19 × 104 by spectrophotometry. Additionally, the electrocatalytic performances towards water oxidation of different concentrations of [Co(H2O)(H3PW11O39)]2− were investigated in the neutral phosphate buffer solution, and it was found that [Co(H2O)(H3PW11O39)]2− anion itself has little activity; the activity of [Co(H2O)(H3PW11O39)]2− solution actually results from dissociated [Co(H2O)6]2+. This work provides a simple way to understand the origin of catalytic water oxidation activity of a POM-based complex.
Isolation and structure determination of a new flavone glycoside from seed residues of seabuckthorn (Hippophae rhamnoides L.)
Creators: name: Zhou, Wenna
name: Yuan, Zhenzhen
name: Li, Gang
name: Ouyang, Jian
name: Suo, Yourui
name: Wang, Honglun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: In this study, a valid method was established for the isolation and purification of flavone glycosides from Hippophae rhamnoides L. seed residues using high-speed counter-current chromatography in one step, with a solvent system of ethyl acetate-methanol-n-butyl alcohol-water (9:1:0.5:9, v/v/v/v). A total of 28.8 mg compound I and 57.3 mg compound II were obtained from 200 mg of flavone H-glycosides rich extract, with purities of 98.3 and 96.4%, respectively. The structures of two compounds were identified by MS and NMR. 3-O-β-D-Sophorosylkaempferol-7-O-{3-O-[2(E)-2,6-dimethyl-6-hydroxyocta-2,7-dienoyl]}-α-L-rhamnoside is compound I and compound II named hippophanone is a new compound were identified by MS and NMR. The method was efficient and convenient, which could be used for the preparative separation of flavone glycosides from H. rhamnoides L. seed residues.
Data Table of Čḯxʷicən Fish Bones [Structured Data from Open Context]
Creators: name: Anthony R Hofkamp
name: Kathyrn A Mohlenhoff
name: Reno Nims
name: Patrick Rennaker
name: J Shoshana Rosenberg
name: Laura M Syvertston
name: Virginia L Butler
name: Kristine M Bovy
name: Sarah K Campbell
name: Michael A Etnier
name: Sarah L Sterling
name: Virginia L Butler
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data Table of Čḯxʷicən Fish Bones Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 127-data-table-of-cixwicn-fish-bones.csv contains the tabular data content for this resource in a CSV format.
JSON: The 127-data-table-of-cixwicn-fish-bones.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
Terms of Use, Intellectual Property, and Ethics
Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

Intellectual Property Policies
Terms of Use
Data Governance Principles
Exploring charge and spin fluctuations in infinite-layer cuprate SrCuO$_{2}$ from a phonon perspective
Creators: name: Du, Xin
name: Sun, Pei-Han
name: Gong, Ben-Chao
name: Zhang, Jian-Feng
name: Lu, Zhong-Yi
name: Liu, Kai
Publisher: name: arXiv
Year: 2023
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The infinite-layer cuprate $A$CuO$_2$ ($A=$ Ca, Sr, Ba) has the simplest crystal structure among numerous cuprate superconductors and can serve a prototypical system to explore the unconventional superconductivity. Based on the first-principles electronic structure calculations, we have studied the electronic and magnetic properties of the infinite-layer cuprate SrCuO$_{2}$ from a phonon perspective. We find that interesting fluctuations of charges, electrical dipoles, and local magnetic moments can be induced by the zero-point vibrations of phonon modes in SrCuO$_{2}$ upon the hole doping. Among all optical phonon modes of SrCuO$_{2}$ in the antiferromagnetic Néel state, only the $A_{1}$$_g$ mode that involves the full-breathing O vibrations along the Cu-O bonds can cause significant fluctuations of local magnetic moments on O atoms and dramatic charge redistributions between Cu and O atoms. Notably, due to the zero-point vibration of the $A_{1g}$ mode, both the charge fluctuations on Cu and the electrical dipoles on O show a dome-like evolution with increasing hole doping, quite similar to the experimentally observed behavior of the superconducting $T_c$; in comparison, the fluctuations of local magnetic moments on O display a monotonic enhancement along with the hole doping. Further analyses indicate that around the optimal doping, there exist a large softening in the frequency of the $A_{1g}$ phonon mode and a van Hove singularity in the electronic structure close to the Fermi level, suggesting potential electron-phonon coupling. Our work reveals the important role of the full-breathing O phonon mode playing in the infinite-layer SrCuO$_{2}$, which may provide new insights in understanding the cuprate superconductivity.
description: 7 pages, 4 figures, 1 table
Association of catalase polymorphisms with primary open-angle glaucoma in a Chinese population
Creators: name: Gong, Bo
name: Shi, Yi
name: Qu, Chao
name: Ye, Zimeng
name: Yin, Yilin
name: Tan, Chang
name: Shuai, Ping
name: Li, Jing
name: Guo, Xiaoxin
name: Cheng, Yilian
name: Yang, Zhenglin
name: Lin, Ying
name: Liu, Xiaoqi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Mental Health

description: Purpose: Many genes have been associated with primary open-angle glaucoma (POAG). This study was conducted to investigate whether catalase (CAT) polymorphisms play a significant role in POAG in a Chinese population. Methods: A cohort of 416 unrelated POAG patients and 997 unrelated control subjects was included in this case–control association study. CAT functional single-nucleotide polymorphisms (SNPs), including rs1001179, rs7943316, and rs769217, were genotyped by SNaPshot method. The genotype and allele frequencies were evaluated using the χ2 tests. The linkage disequilibrium (LD) and haplotype block structure association were examined using the program Haploview (Broad Institute, Cambridge, MA). Results: There was a statistically significant difference for CAT functional SNP rs769217 between POAG cases and controls in the allelic model (p = 0.004, OR = 1.27, 95% CI 1.08–1.49). At this SNP, the allele frequency of the C allele in POAG cases was 0.587, which was higher than that in controls (0.528). However, no association was found for rs1001179 and rs7943316 with POAG. Pairwise LD analysis showed high LD between rs769217 and rs7943316 (D’ = 0.857, r2 = 0.252, confidence bounds 0.71–0.93). After the association analysis for haplotype block structure generated from rs769217 with rs7943316, the data showed no significant association between the cases and controls. Conclusions: This study showed that CAT functional SNP rs769217 was significantly associated with POAG, implying that the CAT gene variants may play a role in the pathogenesis of POAG in the Chinese population.
title: L'invité pisseur
title: The peeing gest
titleType: AlternativeTitle
Creators: name: Vanhove, Martine
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2011
Subjects: subject: Bedja
subject: bej
subject: anthropological_linguistics
subject: linguistique
subject: humour

description: blague scatologique
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Theoretical study on the topotactic transformation and memory effect of M (II) M (III)-layered double hydroxides
Creators: name: Meng, Qingting
name: Yan, Hong
Publisher: name: Taylor & Francis
Year: 2017
Subjects: Physical Sciences not elsewhere classified
Neuroscience
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The topotactic transformation mechanism and memory effect of NiAl- and MgFe- layered double hydroxides (LDHs) are investigated by density functional theory (DFT)-based molecular simulation under their two key thermal decomposition temperatures (365, 800 °C for NiAl-LDHs, and 380, 800 °C for MgFe-LDHs). The results show that at the first temperature, the interlayer carbonate in both LDHs decompose to CO2 and H2O via a monodentate intermediate. During the dehydroxylation of the layers, for both LDHs the metal cations maintain their original distribution within the LDH (0 0 1) facet, while migrating substantially along the c-axis direction, and the layered structure of MgFe-LDHs is destroyed earlier than those of NiAl-LDH. Meanwhile, MgFe-LDHs can keep the memory effect longer than NiAl-LDHs, and the memory effect will disappear when the four-coordinated metal cations increased. At 800 °C, the layered structure of NiAl-LDHs is slightly destroyed, while a complete collapse of layered structure occurs in MgFe-LDHs. These results agree well with the experimental findings. This work will be helpful for the design and preparation of nanocatalysts derived from LDHs precursors.
The State of Digital Education: Engaging with Connected, Blended and Open Learning
Creators: name: Camilleri, Anthony
Publisher: name: figshare
Year: 2017
Subjects: Education

description: The Digital Education Conference held under the Maltese EU Presidency in January 2017 engaged with six key interconnected themes underpinning 21st century education frameworks:
• Openness and Equity in Digital Education
• Systems for Accreditation & Quality Assurance of Online learning
• Best Practices in Policy Design for Digital Education
• Innovation and Digital Pedagogies
• Teachers, learners and digital education
• Future Trends in Digital Education

During the event, the Maltese EU Presidency hosted global policy-makers, thought-leaders, education practitioners and activists from organisations including MIT Media Lab, Creative Commons, UNESCO, Open Society Foundations, Joint Research Centre of the European Commission, Learning Machine and
the Commonwealth of Learning. Participants had the opportunity not just to engage with peers, but also to chart new, pragmatic directions for digital education in Europe.
Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS
Creators: name: Zhang, Er-Fei
name: Ling, Yun
name: Yin, Zi
name: Zhang, Qing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly separate and identify triterpene saponins from the extract of Ardisia mamillata Hance (AMH). In the full scan mass spectrum, the accurate determination of molecular formula is obtained by the predominant ion [M + HCOO]− in negative ion mode. As a result, 30 triterpene saponins are identified or tentatively identified in the plant extract. Of these, 17 triterpene saponins are new compounds. In conclusion, the HPLC-ESI-QTOF-MS/MS is an efficient technique to separate and identify triterpene saponins in complex matrices of medicinal plant.
The acute toxic effects of silver nanoparticles on myocardial transmembrane potential, INa and IK1 channels and heart rhythm in mice
Creators: name: Lin, Cai-Xia
name: Yang, Su-Yu
name: Gu, Jing-Li
name: Meng, Jie
name: Xu, Hai-Yan
name: Cao, Ji-Min
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biological Sciences not elsewhere classified

description: This study focused on the potential toxicity of silver nanoparticles (AgNPs) on cardiac electrophysiology which is rarely investigated. We found that AgNPs (10−9–10−6 g/ml) concentration-dependently depolarized the resting potential, diminished the action potential, and finally led to loss of excitability in mice cardiac papillary muscle cells in vitro. In cultured neonatal mice cardiomyocytes, AgNPs (10−9–10−7 g/ml) concentration-dependently decreased the Na+ currents (INa), accelerated the activation, and delayed the inactivation and recovery of Na+ channels from inactivation within 5 min. AgNPs at 10−8 g/ml also rapidly decreased the inwardly rectifying K+ currents (IK1) and delayed the activation of IK1 channels. Intravenous injection of AgNPs at 3 mg/kg only decreased the heart rate, while at ≥4 mg/kg sequentially induced sinus bradycardia, complete atrio-ventricular conduction block, and cardiac asystole. AgNPs at 10−10–10−6 g/ml did not increase reactive oxygen species (ROS) generation and only at 10−6 g/ml mildly induced lactate dehydrogenase (LDH) release in the cardiomyocytes within 5 min. Endocytosis of AgNPs by cardiomyocytes was not observed within 5 min, but was observed 1 h after exposing to AgNPs. Comparative Ag+ (≤0.02% of the AgNPs) could not induce above toxicities. We conclude that AgNPs exert rapid toxic effects on myocardial electrophysiology and induce lethal bradyarrhythmias. These acute toxicities are likely due to direct effects of AgNPs on ion channels at the nano-scale level, but not caused by Ag+, ROS, and membrane injury. These findings provide warning to the nanomedical practice using AgNPs.
Supplementary material and original data for manuscript RSOS-170516.R1 entitled "Design of cinnamaldehyde amino acids Schiff base compounds based on the quantitative structure activity relationship". from Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure–activity relationship
Creators: name: Wang, Hui
name: Jiang, Mingyue
name: Li, Shujun
name: Hse, Chung-Yun
name: Jin, Chunde
name: Sun, Fangli
name: Li, Zhuo
Publisher: name: The Royal Society
Year: 2017

description: The supplementary file for manuscript RSOS-170516.R1 entitled “Design of cinnamaldehyde amino acids Schiff base compounds based on the quantitative structure activity relationship” contained original data used in this research: The diameter of antifungal inhibition zone of all compounds against two tested fungi, Experimental lgAR versus Calculated lgAR according to the best QSAR model, Grouping results for validation of QSAR model, The validation results of best QSAR models, The synthesis method of new designed compounds, The IR, 1H NMR and MS spectra of two designed compounds.
Figures S1 - S5 from Preparation of core–shell structured CaCO3 microspheres as rapid and recyclable adsorbent for anionic dyes
Creators: name: Zhao, Mengen
name: Chen, Zhenhua
name: Lv, Xinyan
name: Zhou, Kang
name: Zhang, Jie
name: Tian, Xiaohan
name: Ren, Xiuli
name: Mei, Xifan
Publisher: name: The Royal Society
Year: 2017

description: N2 adsorption/desorption isotherms and pore-size distribution (inset) of the obtained core-shell structured CaCO3 MSs; TG analysis of Hesp (a), pure CaCO3 without Hesp and the obtained core-shell structured CaCO3 MSs (b).; SEM image of the CaCO3 MSs after 5 recycling experiments.; N2 adsorption/desorption isotherms and pore-size distribution (inset) of the CaCO3 MSs after 5 recycling experiments.; Three-dimensional histogram of the dye adsorption efficiency on the CaCO3 MSs in 6-10th cycles of the adsorption-desorption.
Emodin extends lifespan of Caenorhabditis elegans through insulin/IGF-1 signaling pathway depending on DAF-16 and SIR-2.1
Creators: name: Zhao, Xuan
name: Lu, Lulu
name: Qi, Yonghao
name: Li, Miao
name: Zhou, Lijun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Mental Health
subject: Computational Biology

description: The naturally occurring anthraquinone emodin has been serving primarily as an anti-bacterial and anti-inflammatory agent. However, little is known about its potential on anti-aging. This investigation examined the effect of emodin on lifespan and focused on its physiological molecular mechanisms in vivo. Using Caenorhabditis elegans (C. elegans) as an animal model, we found emodin could extend lifespan of worms and improve their antioxidant capacity. Our mechanistic studies revealed that emodin might function via insulin/IGF-1 signaling (IIS) pathway involving, specifically the core transcription factor DAF-16. Quantitative RT-PCR results illustrated that emodin up-regulated transcription of DAF-16 target genes which express antioxidants to promote antioxidant capacity and lifespan of worms. In addition, attenuated effect in sir-2.1 mutants suggests that emodin likely functioned in a SIR-2.1-dependent manner. Our study uncovers a novel role of emodin in prolonging lifespan and supports the understanding of emodin being a beneficial dietary supplement. Emodin promotes lifespan and antioxidant capacity of C. elegans through insulin/IGF-1 signaling pathway depending on DAF-16 and SIR-2.1.
Fabrication of dopamine modified polylactide-poly(ethylene glycol) scaffolds with adjustable properties
Creators: name: Shen, Jiali
name: Shi, Dongjian
name: Shi, Chang
name: Li, Xiaojie
name: Chen, Mingqing
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: FOS: Biological sciences

description: Bio-based polymers have been widely used to be as scaffolds for repairing the bone defects. However, the polymer scaffolds are generally lack of bioactivity and cell recognition site. Seeking effective ways to improve the bioactivity and interaction between materials and tissue or cells is clinically important for long-term performance of bone repair materials. In this work, polylactide-b-poly(ethylene glycol)-b-polylactide (PLA-PEG-PLA, PLEL) tri-block copolymers were firstly synthesized by ring-opening polymerization of lactide using PEG with various molecular weights. Inspired by excellent adhesion of dopamine (DA), a facile and effective method was developed to fabricate polydopamine (PDA) and polydopamine/nano-hydroxyapatite (PDA/n-HA) modified PLEL scaffolds by deposition of PDA and PDA/n-HA coating. The surface structure, degradation rates and mineralization of the modified PLEL scaffolds were investigated, and obviously improved after immobilization of PDA and PDA/n-HA coatings. Moreover, the biocompatible results showed a significant increase in cells viability and adhesion. Therefore, the surface modification with PDA and PDA/n-HA could not only adjust the properties of scaffolds, but also reinforce the interfacial adhesion between the PLEL and cells.
Solvent-controlled structural variation from 1D+2D→3D network with coexistence of polycatenation and polythreading to the 2D→3D polythreaded array
Creators: name: Zhang, Chao
name: Wang, Yue
name: Qi, Yan
name: Li, Qun
name: Lv, Zhou
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: This article represents two types of entanglements, [Co2(bibp)(BTB)2][Co(bibp)2(H2O)2] (1) and [Co3(bibp)2(H2O)2(BTB)2]·2H2O·2DMF (2) (bibp = 4,4′-bis(1-imidazolyl)biphenyl and H3BTB = 1,3,5-tris(4-carboxyphenyl)benzene), which are 2-D→3-D polycatenated frameworks formed by parallel catenation of 1-D+2-D→2-D polythreaded motifs based on the double-layered sheet penetrated by ribbons of rings (1) and a 2-D→3-D mutual polythreading of three double-layered sheets with dangling arms (2), which is assembled by the same initial materials by simply changing the volume ratio of water/DMF medium.
Formation of mononuclear and polynuclear d-block metal complexes from 1,4,7-tris(3-hydroxypropyl)-1,4,7-triazacyclononane: crystal structures, spectroscopic studies, and magnetic properties
Creators: name: Zhang, Wen
name: Tang, Qi
name: Feng, Yan-Fang
name: Luo, Kai-Liang
name: Zhang, Zhong
name: Liang, Yu-Ning
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified

description: Four new d-block metal complexes formulated as [NiII(H3thptacn)]Cl2·H2O (1), [MnIV(thptacn)]ClO4 (2), [CuII3(Hthptacn)2](ClO4)2 (3), and [CdII2(H3thptacn)2Cl2][B(C6H5)4]2 (4) were obtained from the macrocyclic ligand 1,4,7-tris(3-hydroxypropyl)-1,4,7-triazacyclononane (H3thptacn) either through solvent diffusion or by evaporation of their solutions. These complexes were characterized by single crystal X-ray structural determination, elemental analysis, and routine spectroscopic methods. Complexes 1 and 2 exhibit similar mononuclear structures with the metal centers being surrounded by both the backbone nitrogen atoms and the pendant coordinating alcohol/alkoxide groups. Complex 3 is a linear trinuclear cluster, where three Cu(II) centers are combined together by the bridging alkoxide groups in a centro-symmetric pattern. Two chloride groups join two Cd(II) atoms each chelated by one triply protonated ligand H3thptacn to afford dinuclear compound 4 with a symmetry center. When coordinating to different d-block metals, the macrocyclic ligand exhibits four types of binding modes with various dissociation status on its pendant alcohol groups and different numbers of these pendant groups participating in coordination. The magnetic measurements revealed significant zero-field splitting for mononuclear Ni(II) and Mn(IV) complexes. A moderate antiferromagnetic interaction between the neighboring Cu(II) centers governs the magnetic properties of 3 with J = −166(3) cm−1.
Quantifying the food requirements and effects of food stress on bumble bee colony development
Creators: name: Rotheray, Ellen L
name: Osborne, Juliet L
name: Goulson, Dave
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Agricultural intensification has led to a reduction in semi-natural areas and in the abundance of wild flowering plants, reducing the availability of floral resources upon which pollinating insects depend. This is widely accepted as one of the major drivers of pollinator declines, but few studies have directly addressed the effects of dietary restrictions on pollinator fitness. Here, we investigated the effects of restricting pollen and nectar supply on bumble bee (Bombus terrestris) colony growth, adult size and number. Colonies required up to 6 g pollen/1 g protein and 50 g sugar to establish a colony of 5 workers, and consumed in excess of 176 g pollen/31 g protein and 1,186 g sugar in their lifetime. Regardless of restrictions on pollen or nectar availability, colonies consumed a ratio of 1 g protein to ~43 g sugar, though free-flying colonies require proportionally more sugar to fuel foraging. Food-limited colonies from an early stage grew little with anything less than ad-lib nectar, while more-established colonies increased in weight even with low levels of nectar suggesting a shortage of resources in early spring may be most damaging to bumble bee colonies. Dietary restriction reduced the number of reproductives produced, but had variable effects on the size of workers and males. Nosema ceranae infection was included as a covariate in analyses and had a significant negative effect on colony growth. This study provides a base line for the developmental requirements of bumble bee colonies, and indicates the effects a resource deficit may have on their development and reproduction.
Formation of mononuclear and polynuclear d-block metal complexes from 1,4,7-tris(3-hydroxypropyl)-1,4,7-triazacyclononane: Crystal structures, spectroscopic studies and magnetic properties
Creators: name: Zhang, Wen
name: Tang, Qi
name: Feng, Yan-Fang
name: Luo, Kai-Liang
name: Zhang, Zhong
name: Liang, Yu-Ning
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified

description: Four new d-block metal complexes formulated as [NiII(H3thptacn)]Cl2·H2O (1), [MnIV(thptacn)]ClO4 (2), [CuII3(Hthptacn)2](ClO4)2 (3) and [CdII2(H3thptacn)2Cl2][B(C6H5)4]2 (4) were obtained from the macrocyclic ligand 1,4,7-tris(3-hydroxypropyl)-1,4,7-triazacyclononane (H3thptacn) either through solvent diffusion or by evaporation of their solutions. These complexes were characterized by single crystal X-ray structural determination, elemental analysis and routine spectroscopic methods. Complexes 1 and 2 exhibit similar mononuclear structures with the metal centers being surrounded by both the backbone nitrogen atoms and the pendant coordinating alcohol/alkoxide groups. Complex 3 is a linear trinuclear cluster, where three Cu(II) centers are combined together by the bridging alkoxide groups in a centro-symmetric pattern. Two chloride groups join two Cd(II) atoms each chelated by one triply protonated ligand H3thptacn to afford dinuclear compound 4 with a symmetry center. When coordinating to different d-block metals, the macrocyclic ligand exhibits four types of binding modes with various dissociation status on its pendant alcohol groups and different numbers of these pendant groups participating in coordination. The magnetic measurements revealed significant zero-field splitting for mononuclear Ni(II) and Mn(IV) complexes. A moderate antiferromagnetic interaction between the neighboring Cu(II) centers governs the magnetic properties of 3 with J = –166(3) cm−1.
title: Donkey, Vixen and Hyena
Creators: name: Langage, Langues Et Cultures D'Afrique
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2017
Subjects: subject: anthropological_linguistics
subject: Folktale
subject: Beja
subject: bej
subject: Annotation

description: Recording session done by the collector/researcher in the speaker's neighbour's house. Were present : the colector/researcher and a female audience (all beja speakers) made of neighbours, relatives and friends, who did not speak.
description: Vixen, in order to save her life from Hyena, plays a trick on a silly donkey which is eaten up bit by bit by Hyena, except the heart, which Vixen manages to steal away from Hyena.
description: Conforms to: Leipzig Glossing Rules
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Relational quality, illness interference, and partner support in Ménière’s disease
Creators: name: Pyykkö, Ilmari
name: Manchaiah, Vinaya
name: Zou, Jing
name: Levo, Hilla
name: Kentala, Erna
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Objective: The current study aimed to better understand how patients and their significant others (SOs) cope with Menière’s disease (MD). Design: The study used a cross-sectional design and the data were collected using questionnaires. Study sample: Seventy-five dyads in which one person had MD. Results: SOs of patients with MD not only experienced activity and participation restrictions but also had positive experiences. In relational quality, the SOs reported uncertainty of their future, limited visits in noisy places, limited activities as walking, watching TV, and participating in social life. The illness interference correlated with the patients' complaints, and most significant was the problem of imbalance. The quality of life was significantly reduced in patients with MD, and the illness interference in terms of quality of life was correlated with the SOs in items related to mood and anxiety. The stress related conditions of the SOs were correlated with two positive items (e.g. alleviating the stress factor). The SOs could also identify one positive item (i.e., improved relationship). Conclusions: Perceptions of MD as interfering in couples’ lives influence dyadic coping in unique ways. The current study identified that dyadic coping has both positive aspects and limitations as a consequence of their partner’s MD.
Supplemental Figure 1. The sequence variations in the MtDNA segments of seven Japanese and North American isolates containing MtORFvar. from A hypervariable mitochondrial protein coding sequence associated with geographical origin in a cosmopolitan bloom-forming alga, Heterosigma akashiwo
Creators: name: Higashi, Aiko
name: Nagai, Satoshi
name: Seone, Sergio
name: Ueki, Shoko
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Sequence differences compared to NEPCC522 in each of the other strains are highlighted with red, blue, and green. A nucleotide deletion in strain Y is marked with a green triangle.