cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Development of a Universal NADH Detection Assay for High Throughput Enzyme Evolution Using Fluorescence Activated Droplet Sorting
Creators: name: Kolaitis, Gerassimos
name: Jain, Ankit
name: Romeis, Dennis
name: Buryska, Tomas
name: Steiger, Matthias
name: Wuerstl, Lena
name: Doering, Manuel
name: Beer, Barbara
name: Stavrakis, Stavros
name: deMello, Andrew J.
name: Sieber, Volker
Publisher: name: ETH Zurich
Year: 2022
Subjects: microfluidics
Enzyme evolution
droplet-based microfluidics
enzyme engineering
FADS
NADH oxidase
Guluronate
Seaweed
Assay

description: Directed evolution is an enzyme engineering approach based on the generation and screening of large mutagenesis libraries, with a view to discovering enzymes with improved properties such as activity, specificity or stability. Recently, droplet-based microfluidics has emerged as a powerful technology enabling ultra-high throughput screening of enzyme libraries and the effective identification and isolation of novel, improved enzyme variants, outperforming conventional enzyme screening platforms by several orders of magnitude in terms of speed and chemical consumption. When using droplet-based platforms fluorescence remains the predominant choice for detection of enzymatic activity due to its high sensitivity and low limits of detection. However, this approach often requires the use of labeled, non-natural substrates, which are typically not commercially available. In addition, fluorescence detection is only suitable for a few enzyme classes such as hydrolases or oxidases, whose reactions can often lead to a fluorescent signal. Herein, we describe an assay that enables fluorescence detection of enzymatic activity through a reaction cascade for the industrially important enzyme subclass of dehydrogenases. By applying a hydrogen peroxide-forming NADH oxidase coupled with peroxidase-catalyzed fluorescence generation, quantification of NADH and dehydrogenase activity becomes possible. We explored the utility of this assay in the evolution of a low performing alcohol dehydrogenase from Sphingomonas species A1 (SpsADH). A fluorescence-activated droplet sorting (FADS) platform was utilized for the screening of a 50,000 variant SpsADH library towards the non-native substrate L-guluronate, a primary component of macroalgae, with the potential to serve as raw material for the bio-based production of chemicals. Significantly, we found an enzyme variant with a 2.6-fold improvement in catalytic efficiency kcat/Km towards the non-native substrate, with only a single round of mutagenesis. The screening of SpsADH libraries confirms the ability of the developed method to enrich active enzyme variants.
description: ChemRxiv
description: ISSN:2573-2293
Increasing Stability of Multistoried Building using Different Grades of Concrete in Column Member Sets at Different Locations
Creators: name: Jamle, Sagar
name: Malviya, Romesh
Publisher: name: figshare
Year: 2020
Subjects: subject: 90506 Structural Engineering
subject: FOS: Civil engineering

description: Concrete is the mainly unquestionable and essential material being used in construction with developing infrastructure throughout the world. The strength of components of a structure creates stiffness regularity for the whole linkage connectivity. As the current study carried out a comparative and understandable behavior of the multistoried building column component with regular and irregular grade of concrete. A software analytical approach is used for the analysis of total five similar building models with same and different grades. Different cases show its different behavior and define its own importance of grade change. At last conclusions have drawn for the efficient and final case that shows optimal location of grade change in concrete columns in a symmetric structure. Grade location case T shows least parametric values after comparison with other grade location cases.
title: Hot Deformation of IN718 with Various Initial Microstrucures- Experiments and State-variable Modelling
Creators: name: Lalvani, Himanshu M.
Publisher: name: The Open University
Year: 2010

description: Significant research has been directed towards characterising the precipitation and dissolution kinetics of the δ phase in IN718, a nickel-base superalloy, but rather less is known about the specific influence of the precipitate on microstructural evolution during thermo-mechanical processing. To investigate the effect of δ precipitate morphology on the hot deformation behaviour of IN718 a series of hot isothermal axi-symmetric compression 'upset' tests have been carried out at fixed nominal strain rates and temperatures relevant to industrial hydraulic press-forging (0.001-0.3/s and 990-1040°C). These test conditions span the δ solvus temperature for the alloy, 1015°C. In particular, three different types of material, each with its own distinct microstructure, were examined: I- solution-treated, δ-free material; II- material containing finely dispersed, intragranular, particulate δ; III- material containing a dense network of intragranular and grain boundary δ platelets along crystallographic habit planes. The presence of δ phase strongly influences both the peak stress and the rate of flow softening. Below the δ solvus temperature the type II material, containing dispersed particulate ö, exhibited the highest peak stress. The type III material, containing acicular δ, exhibited the most significant post-peak softening, whereas the δ-free, type I material, exhibited the lowest peak stresses of all materials. For testing above the solvus temperature the flow behaviour was found to be practically identical for the three microstructures, regardless of the initial presence of δ in two of them. The presence of δ in the microstructure had a marked effect on the evolution of recrystallised fraction and grain size. It also influenced the evolution of texture that resulted into markedly different texture from the classic FCC texture exhibited by solution-treated material after hot deformation. Model predictions from semi-empirical state-variable model in the form of constitutive equations, in the form of flow behaviour and volume fraction recrystallised for solutiontreated IN718, showed good qualitative agreement with measured data. It was found that the model predictions naturally divided the flow behaviour into two regimes of dynamic recovery and dynamic recrystallisation, based on the strain rates employed for hot deformation. This agreed well with observations from microstructure investigations. The model was successfully extrapolated to predict flow behaviour of IN718 available elsewhere in the literature, under temperature and strain rate conditions different from those used in the present work. To further validate the state-variable model, hot compression of a non-uniform double-trucated cone specimen was carried out and the measured volume fraction recrystallised was successfully predicted.
Bound hole states associated to individual vanadium atoms incorporated into monolayer WSe$_2$
Creators: name: Mallet, Pierre
name: Chiapello, Florian
name: Okuno, Hanako
name: Boukari, Hervé
name: Jamet, Matthieu
name: Veuillen, Jean-Yves
Publisher: name: arXiv
Year: 2020
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Doping a two-dimensional semiconductor with magnetic atoms is a possible route to induce magnetism in the material. We report on the atomic structure and electronic properties of monolayer WSe$_2$ intentionally doped with vanadium atoms by means of scanning transmission electron microscopy and scanning tunneling microscopy and spectroscopy. Most of the V atoms incorporate at W sites. These V$_W$ dopants are negatively charged, which induces a localized bound state located 140 meV above the valence band maximum. The overlap of the electronic potential of two charged V$_W$ dopants generates additional in-gap states. Eventually, the negative charge may suppress the magnetic moment on the V$_W$ dopants.
description: 12 pages, 4 figures
Callostethus flavolineatus Fernandes & Grazia 2011
Creators: name: Carrenho, Renan
name: Rodrigues, Higor D. D.
name: Lima, Adriana Carneiro de
name: Schwertner, Cristiano F.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Callostethus
Callostethus flavolineatus

description: Callostethus flavolineatus Fernandes & Grazia, 2011
 Callostethus flavolineatus Fernandes & Grazia in Fernandes et al., 2011: 57-59, figs. 5-7, 9.
 Holotype: ♂, pinned with genitalia in a microvial; [Brazil], Ter.[ritório do] Amapá, Rio Aniconi, 16. VI.[19]59, J. Lane col.
description: Published as part of Carrenho, Renan, Rodrigues, Higor D. D., Lima, Adriana Carneiro de & Schwertner, Cristiano F., 2020, Type specimens of true bugs (Hemiptera: Heteroptera) housed in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-16 in Papéis Avulsos de Zoologia 60 on page 12, DOI: 10.11606/1807-0205/2020.60.17, http://zenodo.org/record/4614885
An Analytical Approach to find out the Efficient Design of Intz Water Tank as per Different Breeze Speed of India
Creators: name: Jamle, Sagar
name: Sapan Chawla
name: Meshram, Kundan
Publisher: name: figshare
Year: 2020
Subjects: subject: 90506 Structural Engineering
subject: FOS: Civil engineering

description: Because of colossal need by the general population, water must be put away and provided by their necessities. Water request isn't steady for the duration of the day. It changes hour to hour. To supply steady measure of water, we must store water. So, to full fill the open water need, water tank should be developed. Limit storehouses and overhead tanks are used to store water, liquid oil, oil-based merchandise and relative liquids. The power assessment of the store or tanks is about the comparable free of the substance thought of the thing. All tanks are arranged as split free structures to discard any spillage. This undertaking gives more or less, the speculation behind the arrangement of liquid holding structure (Elevated roundabout water tank with domed rooftop and cone shaped base) utilizing working stress strategy method. Components are configured in working pressure technique. Breeze speed from 33m/sec to 55 m/s has used in this work along with Fani cyclone effect of 52 m/sec for some areas.
ROAD TRIP
Creators: name: Hanley, Mary Stone
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 3602
subject: Creative and professional writing

description: This collection of poetry follows my life as I journey from the middle 1950s to the present. The underlying motif is transformation--in the world and me, first as a child on family road trips through the South, so long ago that they typically linger as childish recollection with a touch of magic, a testament to resilience and memory. Later poems are about me as a young adult who traveled through the turbulent 60s and 70s. Now as a millennial elder I can reflect on how each moment, each breath was an act of history-making, unbeknownst to me at the time, while I was ahistorical agent, whether as activist, artist, parent, lover, teacher, or simply an observer. Now that I near the end of the journey I can reflect on how change and agency shaped society and my experience and how I changed the world because of it.
Flux melting in BSCCO: Incorporating both electromagnetic and Josephson couplings
Creators: name: Tyagi, Sandeep
name: Goldschmidt, Yadin Y.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Multilevel Monte Carlo simulations of a BSCCO system are carried out including both Josephson as well as electromagnetic couplings for a range of anisotropies. A first order melting transition of the flux lattice is seen on increasing the temperature and/or the magnetic field. The phase diagram for BSCCO is obtained for different values of the anisotropy parameter $γ$. The best fit to the experimental results of D. Majer {\it et al.} [Phys. Rev. Lett. {\bf 75}, 1166 (1995)] is obtained for $γ\approx 250$ provided one assumes a temperature dependence $λ^2(0)/λ^2(T)=1-t$ of the penetration depth with $t=T/T_c$. Assuming a dependence $λ^2(0)/λ^2(T)=1-t^2$ the best fit is obtained for $ γ\approx 450$. For finite anisotropy the data is shown to collapse on a straight line when plotted in dimensionless units which shows that the melting transition can be satisfied with a single Lindemann parameter whose value is about 0.3. A different scaling applies to the $γ=\infty$ case. The energy jump is measured across the transition and for large values of $γ$ it is found to increase with increasing anisotropy and to decrease with increasing magnetic field. For infinite anisotropy we see a 2D behavior of flux droplets with a transition taking place at a temperature independent of the magnetic field. We also show that for smaller values of anisotropy it is reasonable to replace the electromagnetic coupling with an in-plane interaction represented by a Bessel function of the second kind ($K_0$), thus justifying our claim in a previous paper.
description: 12 figures, revtex4
Government Expenditure, Efficiency and Economic Growth: A Panel Analysis of Sub Saharan African Low Income Countries
Creators: name: Kimaro, Edmund Lawrence
name: Keong, Choong Chee
name: Sea, Lau Lin
name: Kimaro, Edmund Lawrence
name: Keong, Choong Chee
name: Sea, Lau Lin
Publisher: name: Unknown
Year: 2017
Subjects: subject: Political Economy
subject: Government expenditure
subject: efficiency
subject: economic growth
subject: Sub Saharan Africa

description: This paper analyzes the impact of government expenditure and efficiency on economic growth of Sub Saharan African low income countries. The paper uses a panel data of 25 Sub-Saharan African low income countries spanning from 2002 – 2015 which are obtained from World Development Indicators (WDI) database. The paper executes panel unit root tests by using ImPesaran-Shin and Fisher ADF tests. The paper also uses Pedroni test to accomplish panel cointegration tests. Finally Generalized Methods of Moments (GMM) is applied to answer the two research questions. The results demonstrate that increasing government expenditure accelerates economic growth of low income countries in Sub Saharan Africa. However, when government expenditure is interacted with government efficiency we find no evidence for government efficiency to boost the impacts of government expenditure on economic growth. Fiscal policy makers in Sub Saharan African low income region should consider the rationale for using their spending to accelerate economic growth.
Energy storage in magnetic textures driven by vorticity flow
Creators: name: Jones, Dalton
name: Zou, Ji
name: Zhang, Shu
name: Tserkovnyak, Yaroslav
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: An experimentally feasible energy-storage concept is formulated based on vorticity (hydro)dynamics within an easy-plane insulating magnet. The free energy, associated with the magnetic winding texture, is built up in a circular easy-plane magnetic structure by injecting a vorticity flow in the radial direction. The latter is accomplished by electrically induced spin-transfer torque, which pumps energy into the magnetic system in proportion to the vortex flux. The resultant magnetic metastable state with a finite winding number can be maintained for a long time because the process of its relaxation via phase slips is exponentially suppressed when the temperature is well below the Curie temperature. We propose to characterize the vorticity-current interaction underlying the energy-loading mechanism through its contribution to the effective electric inductance in the rf response. Our proposal may open an avenue for naturally powering spintronic circuits and nontraditional magnet-based neuromorphic networks.
title: From security to self-expression: The emergent value pattern and the changing role of religion
Creators: name: Lassander, Mika
Publisher: name: The Open University
Year: 2011

description: Religious change is a slow process of adaptation to changed realities of existence where maintaining both emotional and cognitive functioning of the worldview for the individual is central. A shift in human priorities from security to self-expression is linked to increased feelings of security, and after this shift a pluralistic context can further facilitate the development of morality and values that transcend local conventions and traditions. New kinds of worldviews, such as contemporary Paganism, emerge to support and legitimise these new values and modes of interaction. For this thesis, I employed a pragmatic mixed-methods methodology in which psychological value survey data was collected and analysed first, followed by thematic interviews that assist in explaining and interpreting the findings. Young Pagans continue to emphasise the importance of altruism, unlike young Christians, because Paganism works better as a support for altruistic values for people with post-materialist priorities. The majority of Pagans operate on egalitarian modalities of interpersonal relations and their value pattern is characterised by universalistic rather than in-group focused altruism. The lack of a clear collective identity and the consequent lack of an encompassing boundary have shifted the focus in Paganism from talking about boundaries and community to talking about social interactions, concrete relationships between individuals, and to recognising the innate human need to cultivate these relationships. In short, research about Paganism illustrates the way in which contextual factors slowly change the type of people's worldview, without implying increasing rationality; rather, frameworks that have been like templates - providing exemplars - are restyled as trellises that provide footholds to support individual growth.
Quasiclassical theory of $C_4$-symmetric magnetic order in disordered multiband metals
Creators: name: Dzero, Maxim
name: Khodas, Maxim
Publisher: name: arXiv
Year: 2020
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Recent experimental studies performed in the normal state of iron-based superconductors have discovered the existence of the $C_4$-symmetric (tetragonal) itinerant magnetic state. This state can be described as a spin density wave with two distinct magnetic vectors ${\vec Q}_1$ and ${\vec Q}_2$. Given an itinerant nature of magnetism in iron-pnictides, we develop a quasiclassical theory of tetragonal magnetic order in disordered three-band metal with anisotropic band structure. Within our model we find that the $C_4$-symmetric magnetism competes with the $C_2$-symmetric state with a single ${\vec Q}$ magnetic structure vector. Our main results is that disorder promotes tetragonal magnetic state which is in agreement with earlier theoretical studies.
description: 10 pages, 4 figures
Catulona lucida Campos & Grazia 2004
Creators: name: Carrenho, Renan
name: Rodrigues, Higor D. D.
name: Lima, Adriana Carneiro de
name: Schwertner, Cristiano F.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Catulona
Catulona lucida

description: Catulona lucida Campos & Grazia, 2004
 Catulona lucida Campos & Grazia in Campos et al., 2004: 4-7, figs. 3-9.
 Paratypes: 3♂, 1♀, pinned; [Brazil], São Paulo, Batatais, 12-43. XII-1943, Padre P. col.
description: Published as part of Carrenho, Renan, Rodrigues, Higor D. D., Lima, Adriana Carneiro de & Schwertner, Cristiano F., 2020, Type specimens of true bugs (Hemiptera: Heteroptera) housed in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-16 in Papéis Avulsos de Zoologia 60 on page 12, DOI: 10.11606/1807-0205/2020.60.17, http://zenodo.org/record/4614885
Double Digit Economic Growth vs. Social Wellbeing in Ethiopia: A Cross-Country Comparison
Creators: name: Senbet, Dawit
name: Wodajo, Tadesse
name: Senbet, Dawit
name: Wodajo, Tadesse
Publisher: name: Unknown
Year: 2017
Subjects: subject: Food Security and Poverty
subject: real Gross Domestic Product
subject: real GDP
subject: real GDP per capita
subject: economic growth
subject: social wellbeing
subject: Granger causality
subject: cointegration
subject: Ethiopia
subject: Multidimensional Poverty Index
subject: MPI

description: Ethiopia has been reporting double digit economic growth rates over the last decade, while at the same time being ranked as one of the impoverished nations in the world. Despite the 11.0 percent average annual real GDP growth rate since 2004, the Oxford Poverty and Human Development Initiative consistently ranks Ethiopia among the bottom three nations based on Multidimensional Poverty Index (MPI). In this paper, we investigate whether the reported economic growth has enhanced the wellbeing of the ordinary people. To address this objective, we employ three strategies. First, we divide the last two and half decades into pre- and post-2004 years, based on when Ethiopia has started registering double digit growth, to enable us conduct a pre- and postdouble digit growth analyses. Second, we select other three countries also ranked as the poorest countries based on MPI, and compare their performances vis-à-vis Ethiopia using selected social welfare and human development indicators drawn from the World Development Indicators. Third, we use Johansen cointegration and Granger causality tests to examine the impact of economic growth on these social wellbeing measures. Our results show that one, the significant jump in economic growth is not matched by most of the social wellbeing measures. Two, there is no or little significant difference, in terms of these measures, between Ethiopia and the other impoverished countries that reported much slower economic growth than Ethiopia. Three, based on Johansen cointegration and Granger causality tests, we find no significant impact of the reported economic growth on the selected social wellbeing measures. In other words, there is no evidence of economic growth enhancing social wellbeing in Ethiopia.
Superconductivity near the vibrational mode instability in MgCNi3
Creators: name: Ignatov, A.
name: Savrasov, S. Y.
name: Tyson, T. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: To understand the role of electron-phonon interaction in superconducting MgCNi$_{3}$ we have performed density functional based linear response calculations of its lattice dynamical properties. A large coupling constant $% λ$= 1.51 is predicted and contributing phonons are identified as displacements of Ni atoms towards octahedral interstitials of the perovskite lattice. Instabilities found for some vibrational modes emphasize the role of anharmonic effects in resolving experimental controversies.
description: 4 pages, 4 eps figures, replaces the older version
Convolutional Neural Networks and a Transfer Learning Strategy to Classify Parkinson's Disease from Speech in Three Different Languages
Creators: name: Vásquez-Correa, J. C.
name: Arias-Vergara, T.
name: Rios-Urrego, C. D.
name: Schuster, M.
name: Rusz, J.
name: Orozco-Arroyave, J. R.
name: Nöth, E.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Machine Learning (cs.LG)
subject: Computation and Language (cs.CL)
subject: Audio and Speech Processing (eess.AS)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Parkinson's disease patients develop different speech impairments that affect their communication capabilities. The automatic assessment of the speech of the patients allows the development of computer aided tools to support the diagnosis and the evaluation of the disease severity. This paper introduces a methodology to classify Parkinson's disease from speech in three different languages: Spanish, German, and Czech. The proposed approach considers convolutional neural networks trained with time frequency representations and a transfer learning strategy among the three languages. The transfer learning scheme aims to improve the accuracy of the models when the weights of the neural network are initialized with utterances from a different language than the used for the test set. The results suggest that the proposed strategy improves the accuracy of the models in up to 8\% when the base model used to initialize the weights of the classifier is robust enough. In addition, the results obtained after the transfer learning are in most cases more balanced in terms of specificity-sensitivity than those trained without the transfer learning strategy.
ROAD TRIP
Creators: name: Hanley, Mary Stone
Publisher: name: American University
Year: 2023

description: This collection of poetry follows my life as I journey from the middle 1950s to the present. The underlying motif is transformation--in the world and me, first as a child on family road trips through the South, so long ago that they typically linger as childish recollection with a touch of magic, a testament to resilience and memory. Later poems are about me as a young adult who traveled through the turbulent 60s and 70s. Now as a millennial elder I can reflect on how each moment, each breath was an act of history-making, unbeknownst to me at the time, while I was ahistorical agent, whether as activist, artist, parent, lover, teacher, or simply an observer. Now that I near the end of the journey I can reflect on how change and agency shaped society and my experience and how I changed the world because of it.
Improving Access to Livestock Markets for Sustainable Rangeland Management
Creators: name: Kihiu, Evelyne Nyathira
name: Amuakwa-Mensah, Franklin
name: Kihiu, Evelyne Nyathira
name: Amuakwa-Mensah, Franklin
Publisher: name: Unknown
Year: 2017
Subjects: subject: Land Economics/Use
subject: Livestock Production/Industries
subject: Marketing
subject: FOS: Economics and business
subject: Extensive livestock production
subject: market access
subject: ecological-economic model
subject: positive mathematical programming (PMP) model
subject: Kenya

description: Productivity of rangelands in Kenya is affected by increasing crop farming especially in more fertile range areas. Among the key factors driving the encroachment of crops on rangelands are the changing opportunities brought about by markets. We hypothesize that the existing market inefficiencies characterizing livestock markets, especially the price disincentives that livestock producers face, are major risks rangelands face. To analyze the effect of livestock market conditions on rangeland management, we draw on household survey and economic modeling tools. We find that traders’ rent seeking behavior and high transport costs act as disincentives to livestock producers’ participation in livestock markets and influence their decisions in seeking alternative rangeland uses to sustain livelihoods. However, improved livestock market access enhances livestock producers’ livelihoods and the stewardship of the ecosystems thus reducing pastoralists’ vulnerability to ecological climate variability associated with rangelands.
Interest Rate Liberalization, Financial Development and Economic Growth in subSaharan African Economies
Creators: name: Tajudeen, Egbetunda
name: Taofeek Olusola, Ayinde
name: AbdulGaniy Ademola, Balogun
name: Tajudeen, Egbetunda
name: Taofeek Olusola, Ayinde
name: AbdulGaniy Ademola, Balogun
Publisher: name: Unknown
Year: 2017
Subjects: subject: Financial Economics
subject: Interest rate
subject: Financial development
subject: Economic Growth
subject: Liberalisation
subject: Panel

description: This study considers a structural interaction of the interest rate liberalisation-growth nexus; through the inclusion of financial development variables, for sub-Saharan African economies spanning the periods 1980-2012. Coupled with the institutional theory of growth, this study relies on the McKinnon-Shaw framework and, given its merits over conventional tests, a battery of panel unit-root tests was used to purify our data off spurious regression estimates. Later, both panel cointegration and panel error correction models were employed for empirical investigations. From the results obtained, it was evident that other factors such as the openness on trade and price stability are much more significant for interest rate liberalisation and economic growth in sub-Saharan African countries. More so, the extent as well as degree of financial development relatively assisted in reducing interest rate; further facilitates investment and then engendered growth. Theoretically, this study aligns with the McKinnon-Shaw hypothesis of interest rate-growth nexus. Interestingly, the results show that public institutions have been found significantly detrimental at driving the growth process of the sub-Saharan African economies. From the foregoing, the level of financial development, price stability and institutional arrangement should be properly attended to for effective and far-reaching policy suggestions in sub-Saharan African economies.
THE 1895 BOSTON PUBLIC LIBRARY: MONUMENTALITY, COSMOPOLITANISM, AND DEMOCRATIC VALUES IN THE ‘PALACE FOR THE PEOPLE’
Creators: name: Robinson, Adam
Publisher: name: American University
Year: 2023

description: Completed in 1895, the Boston Public Library at Copley Square conveys the bold cultural nationalism of the United States at the turn of the century. Created through the collaborative efforts of an impressive roster of leading American architects, artisans and artists, the building’s design and decoration claims a heightened status for American artistic achievement in an era of unprecedented economic, technological and cultural progress. The library’s architects and designers navigated a delicate balance between the needs and wishes of a diverse group of stakeholders—the cultural elite, the institution itself, and a rapidly expanding and increasingly diverse metropolis—fundamentally shaping the concept of the large municipally-funded public library for the rest of the United States. Their choices reveal overlapping and sometimes opposing ideals of the American Renaissance, City Beautiful, and Public Library Movements during this period. Various scholars have already tackled the topic of the Boston Public Library, frequently focusing on its celebrated architecture or individual aspects of its decoration—the murals by Puvis de Chavannes, Edwin Austin Abbey or John Singer Sargent; the sculptural contributions of Frederick MacMonnies, Daniel Chester French or Augustus Saint-Gaudens. Instead, this thesis is organized around broad categorical affinities between some of the most prominent artistic and social undercurrents animating the American Renaissance, City Beautiful, and Public Library Movements at the turn of the century: monumentality, cosmopolitanism, and democratic values.
Paper-based laser-pyrolyzed electrofluidics: an electrochemical platform for capillary-driven diagnostic bioassays
Creators: name: Bezinge, Léonard
name: Lesinski, Jake M.
name: Suea-Ngam, Akkapol
name: Richards, Daniel A.
name: deMello, Andrew J.
name: Shih, Chih-Jen
Publisher: name: ETH Zurich
Year: 2023

description: Microfluidic paper-based analytical devices (uPADs) are indispensable tools for disease diagnostics. The integration of electronic components into uPADs enables new device functionalities and facilitates the development of complex quantitative assays. Unfortunately, current electrode fabrication methods often hinder capillary flow, considerably restricting uPAD design architectures. Here, we present laser-induced graphenization as an approach to fabricate porous electrodes embedded into cellulose paper. The resulting electrodes not only have high conductivity and electrochemical activity, but also retain wetting properties for capillary transport. We demonstrate paper-based electrofluidics, including (i) a lateral flow device for injection analysis of alkaline phosphatase in serum and (ii) a vertical flow device for quantitative detection of HPV16 with a CRISPR-based assay. We expect that this platform will streamline the development of diagnostic devices that combine the operational simplicity of colorimetric lateral flow tests with the added benefits and possibilities offered by electronic signaling.
description: ChemRxiv
description: ISSN:2573-2293
Zeros of the order parameter of d_{x^2-y^2} superconducting film in the presence of uniform current
Creators: name: Kabanov, V. V.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We show that additional p-wave component is generated in the pure d-wave superconductor in the presence of the uniform current. When the current flows in the antinodal direction the spectrum has a gap over all Fermi surface. If the current flows in the nodal direction, the gap opens only in the direction parallel to the current. The correction to the current due to the p-wave component of the order parameter is linear in vector potential. We show, that the spin-orbit coupling may be responsible for the additional component of the order parameter.
description: 3 pages
THE 1895 BOSTON PUBLIC LIBRARY: MONUMENTALITY, COSMOPOLITANISM, AND DEMOCRATIC VALUES IN THE ‘PALACE FOR THE PEOPLE’
Creators: name: Robinson, Adam
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 3601
subject: Art history, theory and criticism
classificationCode: 4610
subject: Library and information studies

description: Completed in 1895, the Boston Public Library at Copley Square conveys the bold cultural nationalism of the United States at the turn of the century. Created through the collaborative efforts of an impressive roster of leading American architects, artisans and artists, the building’s design and decoration claims a heightened status for American artistic achievement in an era of unprecedented economic, technological and cultural progress. The library’s architects and designers navigated a delicate balance between the needs and wishes of a diverse group of stakeholders—the cultural elite, the institution itself, and a rapidly expanding and increasingly diverse metropolis—fundamentally shaping the concept of the large municipally-funded public library for the rest of the United States. Their choices reveal overlapping and sometimes opposing ideals of the American Renaissance, City Beautiful, and Public Library Movements during this period. Various scholars have already tackled the topic of the Boston Public Library, frequently focusing on its celebrated architecture or individual aspects of its decoration—the murals by Puvis de Chavannes, Edwin Austin Abbey or John Singer Sargent; the sculptural contributions of Frederick MacMonnies, Daniel Chester French or Augustus Saint-Gaudens. Instead, this thesis is organized around broad categorical affinities between some of the most prominent artistic and social undercurrents animating the American Renaissance, City Beautiful, and Public Library Movements at the turn of the century: monumentality, cosmopolitanism, and democratic values.
Peptide-Directed Attachment of Hydroxylamines to Specific Lysines of IgG Antibodies for Bioconjugations with Acylboronates
Creators: name: Tanriver, Matthias
name: Müller, Marco
name: Richards, Daniel
name: Majima, Sohei
name: deMello, Andrew J.
name: Bode, Jeffrey
Publisher: name: ETH Zurich
Year: 2023
Subjects: Antibodies
Affinity peptide
Conjugation
Antibody-drug conjugate
KAT ligation

description: The role of monoclonal antibodies as vehicles to deliver payloads has evolved as a powerful tool in cancer therapy in recent years. The clinical development of therapeutic antibody-conjugates with precise payloads holds great promise for targeted therapeutic interventions. The use of affinity-peptide mediated functionalization of native off-the-shelf antibodies offers an effective approach to selectively modify IgG antibodies with a drug antibody ratio (DAR) of 2. Here, we report the traceless, peptide-directed attachment of two hydroxylamines to native IgGs followed by chemoselective KAT ligation with quinolinium acyltrifluoroborates (QATs), which provide enhanced ligation rates with hydroxylamines under physiological conditions. By applying KAT ligation to the modified antibodies, conjugation of small molecules, proteins, and oligonucleotides to off-the-shelf IgGs proceeds efficiently, in good yields, and with simultaneous cleavage of the affinity peptide-directing moiety.
description: ChemRxiv
description: ISSN:2573-2293
Cyrtocoris egeris Packauskas & Schaefer 1998
Creators: name: Carrenho, Renan
name: Rodrigues, Higor D. D.
name: Lima, Adriana Carneiro de
name: Schwertner, Cristiano F.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pentatomidae
Cyrtocoris
Cyrtocoris egeris

description: Cyrtocoris egeris Packauskas & Schaefer, 1998
 Cyrtocoris egeris Packauskas & Schaefer, 1998: 373-375, figs. 3, 6-7, 15.
 Paratypes: 1♀, pinned; Ecuad [or], Balzapamba, no date, R. Haensch S. col. 1♂, pinned; Brasil, SP [São Paulo], S[ão]. Sebastião, Barra do Una, 08. VII.[1]961, K. Lenko col. 1♀, pinned; Brasil, São Paulo, Barueri, 24.IV.1955, K. Lenko col. 1♀, pinned; Brasil, São Paulo, Barueri, K. Lenko 26.I.1955, K. Lenko col. 1♀, pinned; Brasil, São Paulo, Barueri, K. Lenko 31. XII.1954, K. Lenko col. 1♀, pinned; Brasil, SP [São Paulo], Mogi Guaçu, Faz [enda]. Campinas, XII.29-31.1969, JM e BA Campbell col. 1♀, pinned; [Brazil], R [io de] Janeiro, Corcovado, 01. XII.1961 Warner col. 1♀, pinned; Brasil, E[spirito]. Santo, Corrego do Itá, XI-XII-1956, W. Zikan col. 4♀, 3♂, pinned; Brasil, Goias, Jataí, Faz [enda]. Aceiro, X.1962, Exp [edição]. Dep [artamento]. Zool [ogia]. 1♀, pinned; Brasil, São Paulo, Itu, Faz [enda]. Pau D’alho, XII.1956, U. Martins col. 1♀, pinned; [Brazil], Goiás, Anapolis, V.1939, P.J. Ribeiro col. 1♀, pinned; [Brazil],[Minas Gerais], Monte Alegre, Sta. [Santa] Maria, Alt [itude]. 1.100 m [e]t[er]s. 24-30.XI.1942, F. Lane col. 3♀, 1♂, pinned; BR [Brazil], Rio de Janeiro, Nova Friburgo, XII. 1976, Mury, Gred & Guimarães col. 1♀, pinned; BR [Brazil], Rio de Janeiro, Nova Friburgo, XII.1980, Mury, Gred & Guimarães. 1♀, pinned; [Brazil], RJ [Rio de Janeiro], Nova Friburgo, XII.1961, J.H. Guimarães col. 1♀, pinned; [Brazil], RJ [Rio de Janeiro], Nova Friburgo, XII.1975, J.H. Guimarães col. 1♀, 1♂, pinned; Brasil, SC [Santa Catarina], Nova Teutonia, III.1966, F. Plaumann col. 1♀, 1♂, pinned; [Brazil], E.S [Espirito Santo], Linhares, Parque Sooretama, 17-27.X.1962, F.S. Pereira col. 3♀, pinned; Brasil, S.P. [São Paulo], Rio Claro, 18.I.1962, Biasi, Reichardt col. 1♀, pinned; [Brazil], São Paulo, Cidade Jardim, 23.II.1941 F. Lane col. 1♀, pinned; [Brazil], São Paulo, Osasco, 15.IV.1938, F. Lane col. 1♀, pinned; [Brazil], S[ão]. Paulo, S [erra]. Negra, Sítio B[oa]. Vista, 20.III.1943, Lima col. 2♀, 3♂, pinned; [Brazil], S.[ão]. Paulo, Serra Negra, Sítio Boa Vista, 20.III.1943, Lima col. 1♀, pinned; [Brazil], S.[ão]. P[aulo]., Serra Negra, Sítio Boa Vista, 20.III.1943, Lima col.
description: Published as part of Carrenho, Renan, Rodrigues, Higor D. D., Lima, Adriana Carneiro de & Schwertner, Cristiano F., 2020, Type specimens of true bugs (Hemiptera: Heteroptera) housed in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-16 in Papéis Avulsos de Zoologia 60 on page 12, DOI: 10.11606/1807-0205/2020.60.17, http://zenodo.org/record/4614885
The Impact of Informal Economy on the Interest Rate Pass-through: Evidence from an ARDL model
Creators: name: Patrick, Chileshe M.
name: Akanabi, Olusegun Ayodele
name: Patrick, Chileshe M.
name: Akanabi, Olusegun Ayodele
Publisher: name: Unknown
Year: 2017
Subjects: subject: Financial Economics
subject: ARDL
subject: Interest Rate Pass-through
subject: Informal Economy
subject: Monetary Policy
subject: Zambia

description: In this study, we investigated the impact of the size of the informal economy on the interest rate pass-through. Results from an ARDL model showed that higher levels of the informal sector are associated with higher lending rates. Furthermore, the results indicated that the effect of the informal economy is much stronger in the long-run compared to the short-run. Finally, the results indicated that in both the short run and long run existence of an informal economy dampens the transmission of changes in the policy rate to retail rates as expected from theory and empirical evidence
Polaron Crossover and Bipolaronic Metal-Insulator Transition in the Holstein model at half-filling
Creators: name: Capone, M.
name: Carta, P.
name: Ciuchi, S.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The evolution of the properties of a finite density electronic system as the electron-phonon coupling is increased are investigated in the Holstein model using the Dynamical Mean-Field Theory (DMFT). We compare the spinless fermion case, in which only isolated polarons can be formed, with the spinful model in which the polarons can bind and form bipolarons. In the latter case, the bipolaronic binding occurs through a metal-insulator transition. In the adiabatic regime in which the phonon energy is small with respect to the electron hopping we compare numerically exact DMFT results with an analytical scheme inspired by the Born-Oppenheimer procedure. Within the latter approach,a truncation of the phononic Hilbert space leads to a mapping of the original model onto an Anderson spin-fermion model. In the anti-adiabatic regime (where the phonon energy exceeds the electronic scales) the standard treatment based on Lang-Firsov canonical transformation allows to map the original model on to an attractive Hubbard model in the spinful case. The separate analysis of the two regimes supports the numerical evidence that polaron formation is not necessarily associated to a metal-insulator transition, which is instead due to pairing between the carriers. At the polaron crossover the Born-Oppenheimer approximation is shown to break down due to the entanglement of the electron-phonon state.
description: 19 pages, 15 figures
Reactions to Interpersonal Feedback: Self-Concept Change And Affiliation Choice In Individuals With Low Self-Esteem, Depressive, And Borderline Personality Disorder Symptoms
Creators: name: Mitchell, Jenny E.
Publisher: name: ProQuest
Year: 2023
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: Though some previous research has demonstrated that individuals with low self-esteem, borderline personality disorder, and depressive symptoms process interpersonal feedback differently such that they tend to prefer more negative evaluations than controls do, other research has delineated certain limitations and conditions under which these biases are not demonstrated. The current study aimed to address whether or not affiliation preferences and processing differences by those with borderline personality disorder symptoms are mediated by self-esteem. This study also implements a complex paradigm with negative and positive feedback on both strengths and weaknesses to assess whether different feedback is preferred depending on individuals’ own feelings about traits. Additionally, this study sought to determine mechanisms underlying previous research showing that individuals with borderline personality disorder have a negative bias such that they incorporate more negative feedback into their self-concept than controls do. The current study implemented valenced structured feedback from four false evaluators to examine how individuals with borderline personality disorder symptomology differentially react to interpersonal feedback in terms of affiliation choices and self-concept change. Undergraduate participants (n = 107) wrote about their strengths and weaknesses, received feedback from four evaluators, ranked their preference and perceptions of evaluators, and rated and re-rated themselves as they compared to others on the traits they had chosen. Results indicated that, when evaluator feedback amplified weaknesses, individuals with higher identity disturbance and individuals with higher difficulties in emotion regulation found feedback to be significantly more believable than did individuals low in identity disturbance and individuals low in difficulties in emotion regulation. Results also demonstrated biased incorporation of feedback such that individuals with greater difficulties in regulating emotions were more likely to worsen their self-views about their weaknesses after receiving overall neutral feedback.
Absolute and relative psoriasis area and severity index (PASI) treatment goals and their association with health-related quality of life
Creators: name: Gerdes, Sascha
name: Körber, Andreas
name: Biermann, Mona
name: Karnthaler, Claudia
name: Reinhardt, Maximilian
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background: Relative Psoriasis Area and Severity Index (PASI) improvement, also called ‘PASI response’, is recommended in major guidelines for assessment of treatment response in psoriasis patients. However, under certain circumstances it has some limitations, e.g. when baseline values are missing or during long-term treatment. Improvement of health-related quality of life (HrQoL) can be measured by the Dermatology Life Quality Index (DLQI). Objective: To evaluate the association of HrQoL and relative and absolute PASI outcomes during therapy. Material and methods: Data of plaque psoriasis patients of two clinical trials (CLEAR and SCULPTURE) were pooled. The rates of patients achieving DLQI 0/1 at week 16 were compared for different categories of absolute PASI and PASI response values. The correlation of DLQI and absolute or relative PASI goals was assessed over 52 weeks. Results: One thousand and fifty-four patients with available assessments of PASI and DLQI were included. 76% of the patients with an absolute PASI ≤ 2 (N = 548) and patients with a 90% improvement in PASI (N = 559) achieved DLQI 0/1 at week 16. Achievement of DLQI 0/1 was equally reflected by absolute PASI and PASI response. Conclusion: Absolute PASI appeared to be a feasible alternative to PASI response for determining treatment success, reflecting HrQoL improvements in an equal manner.