cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anticancer activity of flavonoids isolated from spent hops and their derivatives obtained by microbial transformations
Creators: name: Tronina, Tomasz
name: Bartmanska, Agnieszka
name: Poplonski, Jaroslaw
name: Sordon, Sandra
name: Filip-Psurska, Beata
name: Milczarek, Magdalena
name: Wietrzyk, Joanna
name: Huszcza, Ewa
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Hops are primarily used in beer brewing to add bitterness and flavour to beer. It is also good source of desired, biologically active prenylated flavonoids. The major prenylflavonoids from hops is xanthohumol, which it is known from its various biological properties such as antioxidant [1], anti-inflammatory [2], antibacterial [3], antiviral [3], antifungal [4] and antiplasmodial [5] activities.  Xanthohumol was isolated from spent hops - the CO2 extracted hops, a waste product of the hop processing industry. Xanthohumol was extensively tested as a substrate for microbial transformations using over one hundred and forty strains including bacteria, yeasts and fungi. It was also used for the synthesis of other naturally occuring hop prenylfalvonoids such as isoxanthohumol, 8-prenylnaringenin and their synthetic derivatives. Obtained microbial and synthetic compounds were examinated for antiproliferative activity against human cancer cell lines. Tested flavonoids, among them the natural ones,  showed potent anticancer activity, while several of them were more active than cisplatin, the reference drug used in anticancer therapy. Our studies showed how the antiproliferative activity depends on the molecular structure of prenylated flavonoinds (SAR) and indicates that xanthohumol derivatives can be recognized as potential drugs used in anticancer treatment.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Rosmarinic acid as quorum-quenching compound to attenuate Pseudomonas aeruginosa virulence
Creators: name: Borges, Anabela
name: Sousa, Pedro
name: Saavedra, Maria José
name: Borges, Fernanda
name: Simões, Manuel
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Therapies with antibiotics are meant to affect bacterial growth/viability, causing strong selective pressure on bacteria to develop resistance. Therefore, studies have been conducted in order to break out this vicious cycle by interfering with bacterial systems responsible for pathogenicity. Anti-infective therapies based on the interruption of quorum-sensing (QS) pathways are promising strategies[1,2]. In Pseudomonas aeruginosa, QS plays an imperative role in virulence factor production, biofilm formation and antimicrobial resistance, being recognized as an attractive target for novel antipseudomonal drugs[3]. Due to the recognized biological properties of plant products, in this work the quorum-quenching potential of the polyphenolic rosmarinic acid (RA) on P. aeruginosa was studied.This was achieved by high-throughput QSI screening based on the co-cultivation of P. aeruginosa PA14 wild-type strain with the biosensor PA14-R3. Besides, the mode of QSI was evaluated. The potential of RA to down-regulate pyocyanin production and the study of their effect on biofilm formation was also assessed. RA showed ability to interfere with P. aeruginosa QS circuits affecting both N-3-oxododecanoyl-homoserine lactone production/detection without growth inhibition. Moreover, RA decreased the levels of pyocyanin production but no effect in biofilm formation was found.The overall results emphasize the potential of RA as new P. aeruginosa virulence attenuators.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
JOJOBA SEEDS:  PRIMERY ASSESSMENT IN OXIDATIVE STRESS
Creators: name: Sahla, Belhadj
name: Stéphanie, Dal
name: Olfa, Hentati
name: Abdel Fatteh, El Feki
name: Michel, Pinget
name: Séverine, Sigrist
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Objectives: The aim of the present investigation was to evaluate the anti-oxidant properties of jojoba seeds on an in vitro model of hyperglycemia-induced oxidative stress (OS), both associated to diabetes. Methodology: Jojoba seeds extracts were performed with different increasing polarity solvents (hexane, ethyl acetate, methanol, ethanol and water). OS was induced in pancreatic β-cell lines RINm5f by high concentration of fructose. The viability of RINm5F cells was evaluated by CellTiter® (MTT) in presence of extracts +/- OS. Reactive Oxygen Species (ROS) production was monitored with the fluorescent probe CM-H2DCFDA. Antioxidant enzymes activities (dismutase superoxide: SOD and catalase: CAT) was determined. RINm5f insulin secretion was measured using ELISA test in supernatants. Results: Jojoba seed extracts were nontoxic on RINm5f cells. High concentration of fructose provoked loss of cell viability, increased ROS production, and decreased insulin secretion. Seeds extracts prevented the loss of viability. Different extracts protected against OS, with more efficiency for ethyl acetate, methanol and ethanol extracts. This efficiency was associated with an increase of insulin release and decrease of SOD and CAT activities. Conclusions: These results suggest that jojoba seeds protect RINm5F cells via the activation of CAT and SOD against high fructose induced OS.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Improving the quality of Persian clinical text with a novel spelling correction system
Creators: name: Dashti, Seyed Mohammad Sadegh
name: Dashti, Seyedeh Fatemeh
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Background: The accuracy of spelling in Electronic Health Records (EHRs) is a critical factor for efficient clinical care, research, and ensuring patient safety. The Persian language, with its abundant vocabulary and complex characteristics, poses unique challenges for real-word error correction. This research aimed to develop an innovative approach for detecting and correcting spelling errors in Persian clinical text.
 Methods: Our strategy employs a state-of-the-art pre-trained model that has been meticulously fine-tuned specifically for the task of spelling correction in the Persian clinical domain. This model is complemented by an innovative orthographic similarity matching algorithm, PERTO, which uses visual similarity of characters for ranking correction candidates.
 Results: The evaluation of our approach demonstrated its robustness and precision in detecting and rectifying word errors in Persian clinical text. In terms of non-word error correction, our model achieved an F1-Score of 90.0% when the PERTO algorithm was employed. For real-word error detection, our model demonstrated its highest performance, achieving an F1-Score of 90.6%. Furthermore, the model reached its highest F1-Score of 91.5% for real-word error correction when the PERTO algorithm was employed.
 Conclusions: Despite certain limitations, our method represents a substantial advancement in the field of spelling error detection and correction for Persian clinical text. By effectively addressing the unique challenges posed by the Persian language, our approach paves the way for more accurate and efficient clinical documentation, contributing to improved patient care and safety. Future research could explore its use in other areas of the Persian medical domain, enhancing its impact and utility.
Hydroxytyrosol induces epigenetic changes in chondrocyte response to oxidative stress.
Creators: name: D'Adamo, Stefania
name: Cetrullo, Silvia
name: Guidotti, Serena
name: Mariani, Erminia
name: Borzì, Rosa Maria
name: Flamigni, Flavio
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: OBJECTIVE: To our knowledge, no relationship has been revealed between nutraceutical compounds and microRNA (miR) network in OA models, so far.  Here, we investigated whether and how a miR is implicated in hydroxytyrosol (HT)-mediated chondroprotection following H2O2-promoted oxidative stress through the post-transcriptional modulation of sirtuin-1.
 METHODOLOGY: Human primary chondrocytes and C-28/I2 cell line were treated with 100µM HT 30 minutes before 100µM H2O2 addition. In silico analysis were exploited to select putative miR candidates able to target sirtuin-1 mRNA. Transient transfection approach was performed to examine the effects after modulation of miR levels.
 RESULTS: MiR-9 was identified as a putative regulator of sirtuin-1 and confirmed after luciferase-based gene reporter assay. Moreover, tuning of miR-9 levels is responsible for both cell death induced by H2O2 partly through down-regulation of sirtuin-1 and the protective effect of HT, as observed by trypan blue exclusion and caspase activity assays following transfection of miR-9 inhibitor and mimic.
 CONCLUSION: The molecular dissection of how bioactive compounds exert beneficial effects through induction of epigenetic changes, may disclose an interesting therapeutic tool and represents a research topic that deserves further investigation.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Weakly Contrastive Learning via Batch Instance Discrimination and Feature Clustering for Small Sample SAR ATR
Creators: name: Zhai, Yikui
name: Zhou, Wenlve
name: Sun, Bing
name: Li, Jingwen
name: Ke, Qirui
name: Ying, Zilu
name: Gan, Junying
name: Mai, Chaoyun
name: Labati, Ruggero Donida
name: Piuri, Vincenzo
name: Scotti, Fabio
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In recent years, impressive performance of deep learning technology has been recognized in Synthetic Aperture Radar (SAR) Automatic Target Recognition (ATR). Since a large amount of annotated data is required in this technique, it poses a trenchant challenge to the issue of obtaining a high recognition rate through less labeled data. To overcome this problem, inspired by the contrastive learning, we proposed a novel framework named Batch Instance Discrimination and Feature Clustering (BIDFC). In this framework, different from that of the objective of general contrastive learning methods, embedding distance between samples should be moderate because of the high similarity between samples in the SAR images. Consequently, our flexible framework is equipped with adjustable distance between embedding, which we term as weakly contrastive learning. Technically, instance labels are assigned to the unlabeled data in per batch and random augmentation and training are performed few times on these augmented data. Meanwhile, a novel Dynamic-Weighted Variance loss (DWV loss) function is also posed to cluster the embedding of enhanced versions for each sample. Experimental results on the moving and stationary target acquisition and recognition (MSTAR) database indicate a 91.25% classification accuracy of our method fine-tuned on only 3.13% training data. Even though a linear evaluation is performed on the same training data, the accuracy can still reach 90.13%. We also verified the effectiveness of BIDFC in OpenSarShip database, indicating that our method can be generalized to other datasets. Our code is avaliable at: https://github.com/Wenlve-Zhou/BIDFC-master.
ANTAGONISTIC INFLUENCE OF ANTHOCYANIDINS ON GENOTOXIC EFFECTS OF ALTERNARIA MYCOTOXINS
Creators: name: Aichinger, Georg
name: Beisl, Julia
name: Marko, Doris
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Some mycotoxins produced by Alternaria spp. have been described to be genotoxic, acting – amongst others - via topoisomerase poisoning or oxidative stress. Some recent studies focused on protective effects of different polyphenols against mycotoxins, especially due to their antioxidative properties. Also, our group reported that anthocyanidins like delphinidin counteract the genotoxic effects of topoisomerase poisons.
 Thus, we examined whether delphinidin could help to protect colon cells, exemplified by the HT29 colon cancer cell line, from genotoxic damages caused by alternariol and altertoxin II. We assessed interactions at the level of genotoxicity using the comet assay. For further mechanistic elucidation, we performed DCF assays to assess effects on oxidative stress, and the “ICE” assay to observe topoisomerase-poisoning effects. The mathematical model “independent joint action” was applied to describe observed interactions.
 DEL indeed proved to interact antagonistically with both mycotoxins regarding their DNA-breaking potential. For alternariol, we also observed strong antagonistic effects of delphinidin on the stabilization of TOPO-DNA complexes and on the mycotoxin-induced oxidative stress.
 We conclude that anthocyanidins might contribute to the protection of gastrointestinal cells against Alternaria toxins, providing an initial basis for subsequent studies on the in vivo situation.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Induction of human thyroid cancer cells growth inhibition and apoptosis by xanthohumol, a prenylated chalcone from hops (Humulus lupulus L.)
Creators: name: Carvalho, Daniel
name: Freitas, Jaime
name: Carmo, Alexandre M.
name: Guido, Luís F.
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: The antiproliferative and apoptosis-inducing potential of xanthohumol (XN), a natural prenylated chalcone present in hops and beer, was evaluated on cultured human papillary thyroid cancer (TPC-1) cells. TPC-1 cells were treated with XN concentrations varying from 0.1 to 100 µM for 24, 48 and 72 hours. XN inhibited TPC-1 cancer cell proliferation in a dose-dependent manner by a mechanism that stops or slows down cell division, but preserves cell viability. Additionally, XN treatment at high concentrations (100 µM) significantly decreased cell viability suggesting a possible cytotoxic or pro-apoptotic effect. As evidenced, XN treatment triggered DNA fragmentation in TPC-1 cells and mediated S phase cell cycle arrest and increased activities of caspase-3 and caspase-7. XN at high concentrations induced high levels of free radicals generated by the Fenton reaction, suggesting that the apoptotic effect of XN may be mediated through a pro-oxidant pathway. Taken together, these findings indicate that the anti-carcinogenic effects observed are clearly concentration-dependent and suggest that XN can be a potential chemotherapeutic candidate for thyroid cancer therapy.

 This work was funded by FCT/MEC through national fund and co-financed by FEDER (UID/QUI/50006/2013 – POCI/01/0145/FEDER/007265), under the Partnership Agreement PT2020.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
ResearchBox 3386, 'banana study', https://researchbox.org/3386
Creators: name: Malamatenia Panagiotou
Publisher: name: Zenodo
Year: 2024

description: Box title: 'banana study'   Reference: Malamatenia Panagiotou, Christina Ioannou, Lara Hachem, Qiya Huang, Ediriisa Mugampoza, Konstantinos Gkatzionis, 'Consumer perception of banana waste in response to ripeness: a case study of European and Chinese panels'Note: this backup was created automatically by a ResearchBox bot
Protective effects of xanthohumol enriched-beer in pulmonary arterial hypertension
Creators: name: Silva, Ana
name: Ferreira-Pinto, Manuel
name: Santos, Manuel
name: Costa, Gabriel
name: Nunes, Fábio
name: Moreira-Gonçalves, Daniel
name: Negrão, Rita
name: Henriques-Coelho, Tiago
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Recent evidence demonstrates that polyphenol-enriched alcoholic beverages can be beneficial for several chronic diseases. The purpose of this study was to investigate if consumption of a polyphenol-enriched beer could improve the prognostic of pulmonary arterial hypertension(PAH).
 Male Wistar rats(180-200g) were divided in two groups: Monocrotaline(MCT,sc, 60mg/kg) and Control. Afterwards, different beverages were administered to both groups: 5% ethanol(Control+ETOH, MCT+ETOH) and xanthohumol(XN)-enriched beer(Control+XN, MCT+XN). At days D25-27, animals were submitted to cardiac-stress test, echocardiographic and hemodynamic evaluation, followed by sample collection of cardiac and pulmonary samples for histology and molecular biology.
 MCT+ETOH animals presented a diminished VO2máx(p<0.05vs.Control+ETOH). This impairment was reverted by XN in the MCT-treated groups. MCT+ETOH rats presented an elevation of RV systolic pressure(p<0.01vs.Control+ETOH). This increase was correlated with RV mass(r=0.71,p<0.05), fibrosis(r=0.87,p<0.05) and cardiomyocyte cross sectional area(r=0.24,p<0.05). The ingestion of XN-enriched beer resulted in an attenuation of all these alterations in the MCT groups(p<0.05vs.MCT+ETOH). At pulmonary level, MCT+XN group presented a reduction in the thickness of pulmonary arteries(p<0.05vs.MCT+ETOH). This was accompanied with an attenuation of metalloproteinase 2 and 9(p<0.05vs.MCT+ETOH).
 The present work demonstrates that consumption of polyphenol-enriched beer improved both exercise tolerance and cardiac and pulmonary remodelling in the context of PAH.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
ResearchBox 3396, 'Gender Rating Gap in Online Reviews', https://researchbox.org/3396
Creators: name: Hila  Riemer
name: Andreas Bayerl
name: Yaniv Dover
name: Danny Shapira
Publisher: name: Zenodo
Year: 2024

description: Box title: 'Gender Rating Gap in Online Reviews'   Reference: Andreas Bayerl; Yaniv Dover; Hila Riemer; Daniel Shapira, '¬Gender rating gap in online reviews', Nature Human BehaviorNote: this backup was created automatically by a ResearchBox bot
Soy Isoflavones are positively associated with Tissue Levels of 17β-Estradiol in Human Mammoplasty Specimen but do not affect Fluxes of Estrogen-DNA Adducts determined by Computational-based Metabolic Network Modelling
Creators: name: Pemp, Daniela
name: Schmalbach, Katja
name: Tschiggfrei, Karin
name: Soukup, Sebastian T.
name: Hauptstein, René
name: Brückner, Lotta
name: Kleider, Carolin
name: Geppert, Leo N.
name: Köllmann, Claudia
name: Kulling, Sabine
name: Dandekar, Thomas
name: Ickstadt, Katja
name: Eckert, Peter
name: Neshkova, Iva
name: Esch, Harald L.
name: Lehmann, Leane
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: 17β-estradiol contributes to breast cancer development by induction of proliferation and/or DNA adduct formation. Since beneficial and adverse effects of isoflavones are discussed extensively, their influence on estrogen levels and on fluxes of estrogen-DNA adducts was investigated in 47 mammoplasty specimen.Fluxes of estrogen-DNA adducts were determined by computational-based metabolic network modeling, comprising of 142 reactions of estrogen metabolism and 66 reactions of energy metabolism, using levels of 17β-estradiol and estrone, determined by GC-MS/MS, and transcript levels, determined by TaqMan® qPCR (estrogen metabolism) and RNA sequencing (energy metabolism) as flux constraints.Besides adduct fluxes, dependent variables investigated by stepwise forward selected multiple linear regression models were 17β-estradiol, estrone and 17β-hydroxysteroid dehydrogenase type 2 (oxidation of 17β-estradiol to estrone). Explanatory variables (ExVARs) tested were intake of estrogen-active drugs, smoking, body-mass-index, age, lobular regression, oil and adipocyte content as well as transcript levels (estrogens only). The isoflavones genistein and daidzein were quantified using UHPLC-MS/MS and sum of both was used to generate the ExVAR “aglycones“.“Aglycones“ was significantly positively associated with 17β-estradiol and significantly negatively with estrone as well as (borderline significantly) with transcript levels of 17β-hydroxysteroid dehydrogenase type 2. Yet, metabolic flux to estrogen-DNA adducts was not affected by isoflavones.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Experimental study of the first telescope with a toroidal curved detector
Creators: name: Muslimov, Eduard
name: Lombardo, Simona
name: Behaghel, Thibault
name: Liu, Jiawei
name: Hugot, Emmanuel
Publisher: name: arXiv
Year: 2025
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We describe a practical implementation of the anamorphically curved detector concept. In order to demonstrate its advantages, a telescope lab prototype was developed, built, and tested. It is based on a 4-mirror all-spherical unobscured design, similar to that proposed by D. Shafer. The telescope is open at F/#=5.5 and its extended field of view is 10.6x8 degrees. We explore the design parameter space to demonstrate the change in gain introduced by the curved detector and to substantiate the chosen parameters. If the image surface is curved to the shape of a toroid, the image quality reaches the diffraction limit over the entire field by design. The design was optimized to use standard concave spherical mirrors. The detector was curved down toroidally with an exquisite surface precision of approximately 11 micrometers Peak-to-Valley. The experimental tests of the prototype have shown that use of the toroidally curved detector allows to increase the contrast in the field corner by up to 0.3 units, which is in good agreement with the modeling results. We also propose a few prospective applications of the demonstrated concept.
description: 25 pages, 11 figures, 3 tables
Supplementary document for Multistatic Fiber-Based System for Measuring Mueller Matrix Bidirectional Reflectance Distribution Function - 6089981.pdf
Creators: name: Scarboro, Clifton
name: Kudenov, Michael
name: Doherty, Colleen
name: Balint-Kurti, Peter
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Fabrication Methods and Additional Results Figures
TALE: Training-free Cross-domain Image Composition via Adaptive Latent Manipulation and Energy-guided Optimization
Creators: name: Pham, Kien T.
name: Chen, Jingye
name: Chen, Qifeng
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: We present TALE, a novel training-free framework harnessing the generative capabilities of text-to-image diffusion models to address the cross-domain image composition task that focuses on flawlessly incorporating user-specified objects into a designated visual contexts regardless of domain disparity. Previous methods often involve either training auxiliary networks or finetuning diffusion models on customized datasets, which are expensive and may undermine the robust textual and visual priors of pre-trained diffusion models. Some recent works attempt to break the barrier by proposing training-free workarounds that rely on manipulating attention maps to tame the denoising process implicitly. However, composing via attention maps does not necessarily yield desired compositional outcomes. These approaches could only retain some semantic information and usually fall short in preserving identity characteristics of input objects or exhibit limited background-object style adaptation in generated images. In contrast, TALE is a novel method that operates directly on latent space to provide explicit and effective guidance for the composition process to resolve these problems. Specifically, we equip TALE with two mechanisms dubbed Adaptive Latent Manipulation and Energy-guided Latent Optimization. The former formulates noisy latents conducive to initiating and steering the composition process by directly leveraging background and foreground latents at corresponding timesteps, and the latter exploits designated energy functions to further optimize intermediate latents conforming to specific conditions that complement the former to generate desired final results. Our experiments demonstrate that TALE surpasses prior baselines and attains state-of-the-art performance in image-guided composition across various photorealistic and artistic domains.
description: The 32nd ACM Multimedia Conference (MM '24)
HiQuE: Hierarchical Question Embedding Network for Multimodal Depression Detection
Creators: name: Jung, Juho
name: Kang, Chaewon
name: Yoon, Jeewoo
name: Kim, Seungbae
name: Han, Jinyoung
Publisher: name: arXiv
Year: 2024
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: The utilization of automated depression detection significantly enhances early intervention for individuals experiencing depression. Despite numerous proposals on automated depression detection using recorded clinical interview videos, limited attention has been paid to considering the hierarchical structure of the interview questions. In clinical interviews for diagnosing depression, clinicians use a structured questionnaire that includes routine baseline questions and follow-up questions to assess the interviewee's condition. This paper introduces HiQuE (Hierarchical Question Embedding network), a novel depression detection framework that leverages the hierarchical relationship between primary and follow-up questions in clinical interviews. HiQuE can effectively capture the importance of each question in diagnosing depression by learning mutual information across multiple modalities. We conduct extensive experiments on the widely-used clinical interview data, DAIC-WOZ, where our model outperforms other state-of-the-art multimodal depression detection models and emotion recognition models, showcasing its clinical utility in depression detection.
description: 11 pages, 6 figures, Proceedings of the 33rd ACM International Conference on Information and Knowledge Management (CIKM '24)
GPAPF: A Combined Approach for 3D Body Part Tracking
Creators: name: Raskin, Leonid
name: Rudzsky, Michael
name: Rivlin, Ehud
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: In this paper we present a combined approach for body part tracking in 3D using multiple cameras, called GPAPF. This approach combines annealed particle filtering, which has been shown as effective tracker for body parts, with Gaussian Process Dynamical Model, which is used in order to reduce the dimensionality of the problem. That reduction improves the tracker's performance and increases the tracker's stability and ability to recover from the loosing the target. We also compare GPAPF tracker with the annealed particle filter and show that our tracker has a better performance even for low frame rate sequences.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
Attention and Visual Search : Active Robotic Vision Systems that Search
Creators: name: Tsotsos, John K.
name: Shubina, Ksenia
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: Visual attention is a multi-faceted phenomenon, playing different roles in different situations and for different processing mechanisms. Regardless, attention is a mechanism that optimizes the search processes inherent in vision. This perspective leads to sound theoretical foundation for studies of attention in both machine and in the brain. The development of this foundation and the many ways in which attentional processes manifest themselves will be overviewed. One particular example of a practical robotic vision system that employs some of these attentional processes will be described. A difficult problem for robotic vision systems is visual search for a given target in an arbitrary 3D space. A solution to this problem will be described that optimizes the probability of finding the target given a fixed cost limit in terms of total number of robotic actions the robot requires to find its visual target. A robotic realization will be shown.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
Autonomic Computer Vision Systems
Creators: name: Crowley, James L.
name: Hall, Daniela
name: Emonet, Remi
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: Most computer vision systems perform well under controlled laboratory conditions, but require lengthy set up and "tuning" by experts when installed in new operating conditions. Unfortunately, for most real applications of computer vision, the operating conditions frequently change. These changes degrade system performance and can even cause complete system failure, requiring intervention by a trained engineer. The requirement for installation and frequent maintenance by highly trained experts seriously inhibits the commercial application of computer vision systems. In this talk we discuss ways in which autonomic computing can reduce the cost of installation and configuration, as well as enhance reliability, for practical computer vision systems. We begin by reviewing the origins of autonomic computing. We then describe the design of a computer vision system as a software component within a layered service architecture. We describe techniques for regulation of internal parameters, error detection and recovery, self description, and self configuration for vision systems. These methods will be illustrated with results from the IST projects FAME, CAVIAR and CHIL.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
Free Space Estimation for Autonomous Navigation
Creators: name: Soquet, Nicolas
name: Perrollaz, Mathias
name: Labayrade, Raphaël
name: Aubert, Didier
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: One of the issue in autonomous navigation is the free space estimation. This paper presents an original framework and a method for the extraction of such an area by using a stereovision system. The _v-disparity_ algorithm is extended to provide a reliable and precise road profile on all types of roads. The free space is estimated by classifying the pixels of the disparity map. This classification is performed by using the road profile and the _u-disparity_ image. Each stage of the algorithm is presented and experimental results are shown.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
Gain Adaptive Real-Time Stereo Streaming
Creators: name: Kim, Seon Joo
name: Gallup, D.
name: Frahm, Jan-Michael
name: Akbarzadeh, A.
name: Yang, Q.
name: Yang, R.
name: Nistér, D.
name: Pollefeys, M.
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: This paper introduces a multi-view stereo matcher that generates depth in real-time from a monocular video stream of a static scene. A key feature of our processing pipeline is that it estimates global camera gain changes in the feature tracking stage and efficiently compensates for these in the stereo stage without impacting the real-time performance. This is very important for outdoor applications where the brightness range often far exceeds the dynamic range of the camera. Real-time performance is achieved by leveraging the processing power of the graphics processing unit (GPU) in addition to the CPU. We demonstrate the effectiveness of our approach on videos of urban scenes recorded by a vehicle-mounted camera with auto-gain enabled.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
A Biomimetic Vision Architecture
Creators: name: Draper, Bruce A.
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: The goal of biomimetic vision is to build artificial vision systems that are analogous to the human visual system. This paper presents a software architecture for biomimetic vision in which every major component is clearly defined in terms of its function and interface, and where every component has a analog in the regional functional anatomy of the human brain. We also present an end-to-end vision system implemented within this framework that learns to recognize objects without human supervision.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
Maximum-Likelihood Stereo Correspondence using Field Programmable Gate Arrays
Creators: name: Sabihuddin, Siraj
name: MacLean, W. James
Publisher: name: International Conference on Computer Vision Systems : Proceedings
Year: 2007

description: Estimation of depth within an imaged scene can be formulated as a stereo correspondence problem. Typical software approaches tend to be too slow for real time performance on high frame rate (>= 30fps) stereo acquisition systems. Hardware implementations of these same algorithms allow for parallelization, providing a marked improvement in performance. This paper will explore one such hardware implementation of a maximum-likelihood stereo correspondence algorithm on a Field Programmable Gate Array (FPGA). The proposed ""FastTrack"" hardware implementation is a first stage prototype that demonstrates comparable results to an equivalent software implementation. with the advantage of high-speed (eventually up to 200fps) stereo depth estimation.
description: International Conference on Computer Vision Systems : Proceedings, The 5th International Conference on Computer Vision Systems (ICVS)
Judgement and Decision-Making by Athlete-Team Selectors
Creators: name: Ariyapperuma Ramanayakage, Nilantha Dinesh Ramanayaka
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 350718
subject: Strategy
classificationCode: 520402
subject: Decision making
classificationCode: 350405
subject: Sport and leisure management
classificationCode: 520107
subject: Sport and exercise psychology

description: Submitted in total fulfillment of the requirements for the degree of Doctor of Philosophy to La Trobe Business School, La Trobe University, Victoria, Australia.
Our Practice Newsletter : By Pharmacists For Pharmacists. Issue 35
Creators: name: Yuen, Jamie
name: Domanski, Nicole
Publisher: name: The University of British Columbia
Year: 2024

description: Feature Case: Leveraging Technology to Address Hypertension Management and Adherence. As virtual health care delivery continues to evolve, remote blood pressure monitoring may eventually become routine practice. This case dives into a unique patient case where technology was used as a motivating factor to improve medication adherence and health outcomes.
Manipulation of VEGF-A splicing using natural compounds as a potential therapeutic in diabetic nephropathy
Creators: name: Stevens, Megan
name: Oltean, Sebastian
name: Harper, Steven
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Alternative splicing of vascular endothelial growth factor (VEGF-A) gives rise to isoform families, the pro-angiogenic VEGF-Axxx and the anti-angiogenic VEGF-Axxxb. VEGF-A165b has previously been shown to be protective in several murine models of renal disease, as well as providing cytoprotection to podocytes in culture. This study aimed to investigate whether a blueberry extract that promotes VEGF-A­165b expression, is a potential therapeutic in a mouse model of type I diabetic nephropathy.
 The natural extract had no effect on blood glucose levels, but did delay the onset/progression of albuminuria in diabetic mice, and prevented increases in glomerular water permeability. Diabetic control mice had a reduced glomerular expression of nephrin and reduced glomerular capillary circumference, which were rescued when treated with the natural extract. HUVECs displayed reduced tube formation when treated with the natural extract, which was rescued upon addition of Ab-VEGF-A165b.
 Certain unknown compounds within the blueberry extract are able to switch VEGF-A splicing to promote VEGF-A165b expression in podocytes. The extract plays a protective role in the prevention and treatment of diabetic nephropathy in the DBA/2J type I diabetic mouse model. This study highlights the therapeutic potential of switching VEGF-A splicing to promote VEGF-A165b in diabetic nephropathy.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
EFFECT OF CYCLODEXTRIN AND EXTRACTION METHOD ON PHENOLIC COMPOUNDS EXTRATION FROM RED WINE POMACE
Creators: name: Gracia, María
name: Serrano-Martínez, Ana
name: Hernández-Sánchez, Pilar
name: Guardiola, Lucía
name: Núñez-Delicado, Estrella
name: Lopez-Miranda, Santiago
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Extraction of phenolic compounds has been always conditioned to the use of organic solvents. An alternative to reduce the use of organic solvents in phenolic compounds extraction can be the cyclodextrins (CD). This work aims to determine the effect of cyclodextrins and extraction method on the extraction of phenolic compounds and antioxidant capacity of extracts. Phenolic extractions were made from Monastrel red variety pomace. Extractions were made by ultrasound and microwave at 50ºC during 10’ with aqueous solutions of a-, b-, g-, HP-a-, HP-b-, HP-g-CD 50 mM, water and ethanol/water (1:1 v/v). Total phenolic compounds, procyanidins, flavanols, favonols and antioxidant capacity were measured. The final extraction of total phenolic compounds and antioxidant capacity obtained by using cyclodextrins were higher than those obtained by using water, but lower than those obtained by using ethanol/water. Microwave extraction extracted 75% more of total phenolics than ultrasound. Moreover, CDs had a selective effect on phenolics extraction. Extraction of flavanols and flavonols with CDs were similar to those obtained by using etanol/water. Type of CDs had also a great effect on favonols extraction. In conclusion, CDs could be used as an alternative to organic solvents for the extraction of specific phenolic compounds from pomace.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Fortification of orange juice with antioxidant from orange by-products and evaluation of stability during in vitro digestion
Creators: name: Figueroa, Jorge G.
name: Celi-Bonilla, Xavier
name: Delgado-Sánchez, Jessica
name: González-Arévalo, Soledad
name: Borrás-Linares, Isabel
name: Segura-Carretero, Antonio
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Orange juice production provides large amounts of underutilised by-products that suppose an environmental problem for the food industry, despite their high content in bioactive compounds. The aims of this work have been the fortification of commercial orange juice with bioactive compounds from orange pulp in order to improve its antioxidant activity. Thus, different aqueous orange pulp extracts were encapsulated and incorporated into commercial orange juice at different proportions. The stability of the antioxidant ingredient was followed over 8 weeks. The total phenolic content and the antioxidant capacity of these formulations were measured with different antioxidant procedures. Additionally, the effect of an in-vitro digestion in the antioxidant activity of the fortified juices was studied.

The total phenolic content of the developed ingredient decreased in 34 % during the two first weeks of storage, but after that it remain constant. The results revealed that the commercial orange juice fortified with the encapsulated extract from orange pulp showed an increase of total phenolic content of 10-22 %, while the antioxidant activity of the juice improved in all the antioxidant assays. The addition of the antioxidant extract showed a reduction in the decrease of the antioxidant activity of the juices after de in-vitro digestion.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Beyond Over-smoothing: Uncovering the Trainability Challenges in Deep Graph Neural Networks
Creators: name: Peng, Jie
name: Lei, Runlin
name: Wei, Zhewei
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The drastic performance degradation of Graph Neural Networks (GNNs) as the depth of the graph propagation layers exceeds 8-10 is widely attributed to a phenomenon of Over-smoothing. Although recent research suggests that Over-smoothing may not be the dominant reason for such a performance degradation, they have not provided rigorous analysis from a theoretical view, which warrants further investigation. In this paper, we systematically analyze the real dominant problem in deep GNNs and identify the issues that these GNNs towards addressing Over-smoothing essentially work on via empirical experiments and theoretical gradient analysis. We theoretically prove that the difficult training problem of deep MLPs is actually the main challenge, and various existing methods that supposedly tackle Over-smoothing actually improve the trainability of MLPs, which is the main reason for their performance gains. Our further investigation into trainability issues reveals that properly constrained smaller upper bounds of gradient flow notably enhance the trainability of GNNs. Experimental results on diverse datasets demonstrate consistency between our theoretical findings and empirical evidence. Our analysis provides new insights in constructing deep graph models.
description: CIKM2024
Importance of immune system modulation in anti-inflammatory and antitumoral properties of Resveratrol, a polyphenol of wine
Creators: name: Limagne, Emeric
name: Thibaudin, Marion
name: Chalons, Pauline
name: Végran, Frédérique
name: Mignot, Grégoire
name: Apetoh, Lionel
name: Ghiringhelli, François
name: DELMAS, DOMINIQUE
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Numerous epidemiological studies show that various polyphenols may protect against various diseases such as vascular diseases, cancers and inflammatory pathologies. One of the best known is the polyphenol resveratrol which is a trans-3,4’,5-trihydroxystilbene and seems appear to a great interest in the prevention of these pathologies. We have recently shown that resveratrol could prevent carcinogenesis via an anti-inflammatory action through a modulation of miRNA. This inflammation could promote tumoral progression through a modulation of the immune response. Thus, the objectives of this study were to evaluate the potential effect of resveratrol in the immune response in mice with melanoma.
 Our results highlight that resveratrol modulates differentiation of lymphocytes Th17 which exerts protumoral activity via the interleukin-17 production. Naïve CD4 T cells derived from C57blc/6 mice displayed less capability to differentiate into Th17 cells in vitro after resveratrol treatment. Moreover in mouse model of melanoma (B16F10), resveratrol prevented tumor growth and angiogenesis in an IL-17-dependent manner. This phenomenon could be due to a strong inhibition of the expression of the Th17-specific transcription factor Rorc. This work brings a new mechanism by which resveratrol prevents cancer related inflammation through a modulation of the immune cells and interleukin production.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
Effect of flavonoids on cytochrome P450 activity in the gut – an in vitro food-drug interaction study
Creators: name: Farkas, Orsolya
name: Kovács, Dóra
name: Karancsi, Zita
name: Csikó, György
name: Palócz, Orsolya
Publisher: name: Journal of International Society of Antioxidants in  Nutrition & Health
Year: 2016

description: Cytochrome P450 enzymes have a remarkable role in the xenobiotics metabolism. Oxidation of drugs and food components catalysed by the same isoenzyme can lead to drug-food interactions. Greatest quantity of CYP enzymes can be found in the liver. Nevertheless, the intestinal CYP garniture also contributes to the metabolism of clinically important drugs. Our research focused on the effects of flavonoids on the intestinal CYP enzymes.
 Intestinal epithelial cells (IPEC-J2) were treated by apigenin and apigenin-trimethylether. Phenobarbital was used as CYP inducer, mixture of naphtoflavone and ketoconazole as inhibitor. The CYP1A1, CYP1A2 and CYP3A activities were measured by chemiluminescent assay. Treatment of enterocytes with antipyrine was also performed in order to test possible drug interactions.
 Both flavones worked as significant CYP3A4 inhibitors. There was no significant difference between the inhibitory effects of the flavones at the same dose. However, apigenin-trimethylether combined with the inducer, was a more potent inhibitor, than the apigenin. Antipyrine decreased the enzymatic activity, which effect was enhanced, when antipyrine and apigenin were administered simultaneously.
 In conclusion, our results suggest that both apigenin and its trimethylated derivative can inhibit the intestinal CYP3A, which is the most important role in the metabolism of clinically relevant drugs.
description: Journal of International Society of Antioxidants in  Nutrition & Health, Vol 3, No 4 (2016)
title: Test Derivation for CMOS Iterative Logic Arrays
Creators: name: Sharma, Ravi
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1985

description: Testability criteria for stuck-open (s-op) faults in one-dimensional unilateral iterative logic arrays (ILA) of CMOS combinational cells are considered in this thesis. A functional fault model to represents-op faults i~ an ILA cell is given. The procedure to detect as-op fault needs a pair of test vectors. The first is used to set up the initial conditions required to test the fault and the second is the test which distinguishes between the good and the bad circuit. Based on this approach necessary and sufficient conditions are given for the testability of as-op fault in a CMOS ILA cell. These conditions are extended to include the C-testability for the s-op fault (testing an ILA by a constant number of tests independent of the length of the array). Since some of the tests will be invalidated due to the delays in input changes, additional requirements to be satisfied for the generation of valid test vectors are proposed.