cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Expression of Integrins, Anchorage Dependent Apoptosis and Invasiveness of Multidrug Resistant Human Breast Carcinoma Cells
Creators: name: Berman, A. E.
name: Chubukina, A. N.
name: Kozlova, N. I.
name: Morozevich, G. E.
name: Shtil, A. A.
Publisher: name: Technische Universität Dortmund
Year: 2004
Subjects: subject: anoikis
subject: integrins
subject: multidrug resistance
subject: tumor invasion
subject: 610

description: The aim of the study was to investigate the role of integrins in anchorage dependent apoptosis (anoikis) and in vitro invasion of human breast cancer cell line MCF-7 and its multidrug resistant subline MCF-7Dox. Acquisition of MDR was associated with markedly decreased expression of collagen specific a2ß1 and avß3 integrins, laminin specific a3ß1 and a6ß1 receptors and dramatic up-regulation of fibronectin specific a5ß1 integrin. The MDR subline was substantially more resistant to anoikis than their wild type counterparts. Furthermore, MCF-7Dox cells secreted MMP-9 collagenase and invaded Matrigel. We demonstrate for the first time that stimulation of ß1 integrin signaling strongly sensitizes MCF-7 cells to anoikis.
description: EXCLI Journal ; Vol. 3, 2004
War "Biblisch-Hebräisch" eine Sprache?
Creators: name: Knauf, Ernst Axel
Publisher: name: Zeitschrift für Althebraistik
Year: 1970

description: Zeitschrift für Althebraistik, Bd. 3 Nr. 1 (1990): Zeitschrift für Althebraistik, Band 3, Heft 1
title: Approximate Bayesian Implementation and Exact Maxmin Implementation: An Equivalence
Creators: name: Song, Yangwei
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2022

description: This paper provides a micro-foundation for approximate incentive compati- bility using ambiguity aversion. In particular, we propose a novel notion of ap- proximate interim incentive compatibility, approximate local incentive compatibility, and establish an equivalence between approximate local incentive compatibility in a Bayesian environment and exact interim incentive compatibility in the pres- ence of a small degree of ambiguity. We then apply our result to the implementa- tion of efficient allocations. In particular, we identify three economic settings—including ones in which approximately efficient allocations are implementable, ones in which agents are informationally small, and large double auctions—in which efficient allocations are approximately locally implementable when agents are Bayesian. Applying our result to those settings, we conclude that efficient al- locations are exactly implementable when agents perceive a small degree of ambiguity.
title: Education and Training in Inclusive Welfare States
title: D6.2_Working paper on needed upskilling schemes
titleType: AlternativeTitle
Creators: name: Kangas, Olli
name: Karonen, Esa
name: Kohlgrüber, Michael
name: Behrend, Clara
name: Cuypers, Mathias
name: Götting, Adrian
Publisher: name: TU Dortmund
Year: 2022
Subjects: subject: Education
subject: Training
subject: Digital transformation
subject: Inclusion
subject: Skills
subject: Skill requirements
subject: Skill demands
subject: Social investment
subject: Combined capabilities
subject: Digital skills
subject: Inclusiveness
subject: 300
subject: Weiterbildung
subject: Bildung
subject: Wohlfahrtsstaat
subject: Inklusive Pädagogik

description: This working paper analyses opportunities for inclusiveness in the context of the digital transfor-mation. There are fears that digitalisation will create new cleavages in societies, and there will be gaps in skills needed in digital working life. Older workers and immigrants, in particular, are in a vulnerable position. The theoretical approaches of social investment and combined capabilities stress the needs for upskilling. These are identified to develop digital and non-digital skills to cope with the challenges of the digital transformation. We show that it is not enough to develop indi-vidual capabilities. To really improve inclusiveness, combined capabilities are needed, which take into account institutional arrangements and corresponding public services.
Experimental fast quantum random number generation using high-dimensional entanglement with entropy monitoring
Creators: name: Xu, Feihu
name: Shapiro, Jeffrey H.
name: Wong, Franco N. C.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: A quantum random number generator (QRNG) generates genuine randomness from the intrinsic probabilistic nature of quantum mechanics. The central problems for most QRNGs are estimating the entropy of the genuine randomness and producing such randomness at high rates. Here we propose and demonstrate a proof-of-concept QRNG that operates at a high rate of 24 Mbit/s by means of a high-dimensional entanglement system, in which the user monitors the entropy in real time via the observation of a nonlocal quantum interference, without a detailed characterization of the devices. Our work provides an important approach to a robust QRNG with trusted but error-prone devices.
description: 6 pages, 3 figures
On fake linear cycles inside Fermat varieties
Creators: name: Franco, Jorge Duque
name: Loyola, Roberto Villaflor
Publisher: name: arXiv
Year: 2021
Subjects: subject: Algebraic Geometry (math.AG)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: 14C25, 14C30, 14D07

description: We introduce a new class of Hodge cycles with non-reduced associated Hodge loci, we call them fake linear cycles. We characterize them for all Fermat varieties and show that they exist only for degrees $d=3,4,6$, where there are infinitely many in the space of Hodge cycles. These cycles are pathological in the sense that the Zariski tangent space of their associated Hodge locus is of maximal dimension, contrary to a conjecture of Movasati. Moreover, they provide examples of algebraic cycles not generated by their periods in the sense of Movasati-Sertöz. To study them we compute their Galois action in cohomology and their second-order invariant of the IVHS. We conclude that for any degree $d\ge 2+\frac{6}{n}$, the minimal codimension component of the Hodge locus passing through the Fermat variety is the one parametrizing hypersurfaces containing linear subvarieties of dimension $\frac{n}{2}$, extending results of Green, Voisin, Otwinowska and the second author.
description: Final version to appear in Algebra & Number Theory
Construction of chimeric antibody binding green fluorescent protein for clinical application
Creators: name: Isarankura-Na-Ayudhya, Chartchalerm
name: Prachayasittikul, Virapong
name: Suwanwong, Yaneenart
name: Tantimavanich, Srisurang
Publisher: name: Technische Universität Dortmund
Year: 2005
Subjects: subject: Fc binding
subject: green fluorescent protein
subject: Z-domain
subject: 610

description: A chimeric antibody-binding green fluorescent protein (ZZGFPuv) was successfully constructed and applied as a powerful tool for immunological diagnosis. A gene encoding two repetitive sequences of Z-domain, derivative of IgG-binding B domain of staphylococcal protein A, was fused in-frame to the N-terminus of gfpuv gene. The chimeric gene was subsequently transformed and expressed in various strains of E. coli. Expression of chimeric protein in E. coli strain HB101 resulted in a protein translocation from cytoplasm to periplasmic space and cultivation medium. The chimeric ZZGFPuv could be purified using either IgG Sepharose column or immobilized metal (Cu2+) affinity chromatography. The purified protein migrated in non-denaturing SDS-PAGE as two major bands. A fluorescent band was located at 36 kDa while another band at 48 kDa exhibited non-fluorescence. The fluorescent band was isolated and assessed for IgG-binding via fluorescent emission. The lowest amount of IgG that could be detected by dot immunobinding assay was approximately 630 ng. Indirect immunofluorescent assay for a serological detection of leptospirosis was performed by using the chimeric ZZGFPuv as IgG detector. A strong fluorescent intensity as comparable to that of the fluorescein isothiocyanate (FITC) conjugated system was significantly detected. All these findings support a high feasibility to apply the chimeric Ab-binding GFP for clinical applications in the future.
description: EXCLI Journal ; Vol. 4, 2005
Oscillating paramagnetic Meissner effect and Berezinskii-Kosterlitz-Thouless transition in $Bi_2Sr_2CaCu_2O_{8+δ}$ monolayer
Creators: name: Wang, S. Y.
name: Yu, Y.
name: Hao, J. X.
name: Feng, Y.
name: Zhu, J. J.
name: Lin, Y. S.
name: Xiang, B. K.
name: Ru, H.
name: Pan, Y. P.
name: Gu, G. D.
name: Watanabe, K.
name: Taniguchi, T.
name: Qi, Y.
name: Zhang, Y.
name: Wang, Y. H.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Monolayers of a prototypical cuprate high transition-temperature ($T_C$) superconductor $Bi_2Sr_2CaCu_2O_{8+δ}$ (Bi2212) was recently found to show $T_C$ and other electronic properties similar to those of the bulk. The robustness of superconductivity in an ideal two-dimensional (2D) system was an intriguing fact that defied the Mermin-Wagner theorem. Here, we took advantage of the high sensitivity of scanning SQUID susceptometry to image the phase stiffness throughout the phase transition of Bi2212 in the 2D limit. We found susceptibility oscillated with flux between diamagnetism and paramagnetism in a Fraunhofer-like pattern up till $T_C$. The temperature and sample size-dependence of the modulation period agreed well with our Coulomb gas analogy of a finite 2D system based on Berezinskii-Kosterlitz-Thouless (BKT) transition. In the multilayers, the susceptibility oscillation differed in a small temperature regime below $T_C$ in consistent with a dimensional-crossover led by interlayer coupling. Serving as strong evidence of BKT transition in the bulk, there appeared a sharp superfluid density jump at zero-field and paramagnetism at small fields just below $T_C$. These results unified the phase transitions from the monolayer Bi2212 to the bulk as BKT transition with finite interlayer coupling. This elucidating picture favored the pre-formed pairs scenario for the underdoped cuprates regardless of lattice dimensionality.
title: The Effect of Pension Wealth on Employment
Creators: name: Becker, Sebastian
name: Buslei, Hermann
name: Geyer, Johannes
name: Haan, Peter
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2022

description: This study provides novel evidence about the pension wealth elasticity of employment. For the identification we exploit reform-induced variation of pension wealth that is related to the number of children but which does not affect the implicit tax rate of employment. We use a difference-in-differences estimator based on administrative data from the German pension insurance and find that, on average, the negative employment effect of pension wealth is significant and economically important. Heterogeneity analyses document a strong age pattern showing that the employment effects are driven by behavioral responses of women close to retirement. The age pattern is partly explained by the positive effect of pension wealth on disability pensions after the age of 60.
Expression of prostacyclin-stimulating factor (PSF) in mononuclear cells of human peripheral blood and THP-1 derived macrophage-like cells, and effects of high glucose concentration
Creators: name: Etoh, Takashi
name: Hashimoto, Toshihiko
name: Imamura, Minako
name: Inoguchi, Toyoshi
name: Nawata, Hajime
name: Sekiguchi, Naotaka
Publisher: name: Technische Universität Dortmund
Year: 2005
Subjects: subject: diabetes mellitus
subject: macroangiopathy
subject: macrophage
subject: prostacyclin stimulating factor (PSF)
subject: 610

description: Prostacyclin (PGI2) synthesis by vascular endothelial cells (ECs) decreases in diabetic subjects, possibly leading to development of diabetic angiopathies including that in atherosclerosis. We identified a bioactive peptide, prostacyclin-stimulating factor (PSF), which stimulates PGI2 synthesis in cultured aortic ECs. Our previous studies demonstrated that PSF was predominantly expressed by arterial smooth muscle cells (SMCs) and ECs. We immunohistochemically showed that PSF existed in SMCs of human coronary arteries, and PSF staining was markedly reduced in coronary arterial SMCs of patients with type 2 diabetes and/or myocardial infarction. In the present study, we investigated the existence of PSF in human serum, and effects of glucose on serum PSF levels in patients with type 2 diabetes. Immunoblot analysis revealed the presence of PSF in serum, and showed that serum PSF protein concentration was significantly decreased in type 2 diabetic patients. Moreover, there was a significant negative correlation between serum PSF and HbA1c levels in these patients. Using immunohistochemistry, we also showed that PSF was present in serum and in macrophages (Mfs). PSF mRNA was found in Mfs using reverse transcription-polymerase chain reaction (RT-PCR). In addition, effects of high glucose conditions on PSF production in Mfs were examined by Western blotting, and we showed that PSF significantly decreased when Mfs were cultured in high glucose conditions. These results strongly suggested that decreased PSF production might result in decreased production of PGI_2 in atherosclerotic lesions, thus leading to development of diabetic macroangiopathy and atherosclerosis.
description: EXCLI Journal ; Vol. 4, 2005
Quasiparticle multiplets and 5f electronic correlation in prototypical plutonium borides
Creators: name: Lu, Haiyan
name: Huang, Li
Publisher: name: arXiv
Year: 2022
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: To elucidate the localized-itinerant dual nature and orbital dependent correlations of Pu-5f valence electrons in plutonium borides (PuBx, x=1, 2, 6, 12), the electronic structures are throughout investigated by using the combination of density functional theory and single-site dynamical mean-field method. We not only reproduce the correlated topological insulator of PuB6, but also predict the metallicity in PuBx (x=1, 2, 12). It is found that the momentum-resolved spectral functions, density of states, hybridization functions all indicate partially itinerant 5f states in PuBx (x=1, 2, 6, 12). Especially, quasiparticle multiplets induced noteworthy valence state fluctuations implying the mixed-valence behavior of plutonium borides. Moreover, the itinerant degree of freedom for 5f electrons in PuBx (x=1, 2, 12) is tuned by hybridization strength between 5f states and conduction bands, which is affected by atomic distance between Pu and B atoms. Lastly, 5f electronic correlations encoded in the electron self-energy functions demonstrate moderate 5f electronic correlations in PuB6 and orbital selective 5f electronic correlations in PuBx (x=1, 2, 12). Consequently, the understanding of electronic structure and related crystal structure stability shall shed light on exploring novel 5f electrons states and ongoing experiment research.
description: 16 pages, 5 figure
Victoria Voice of Women (Fall, 1991)
Creators: name: Voice Of Women (Association)
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Women's rights
valueUri: http://id.worldcat.org/fast/1178818
subject: Women--Legal status, laws, etc.
valueUri: http://id.worldcat.org/fast/1176824
subject: Sex discrimination against women
valueUri: http://id.worldcat.org/fast/1114376
subject: Women and war
valueUri: http://id.worldcat.org/fast/1177123
subject: Women--Social conditions
valueUri: http://id.worldcat.org/fast/1176947
subject: Women--Societies and clubs
valueUri: http://id.worldcat.org/fast/1176970
subject: Nuclear disarmament
valueUri: http://id.worldcat.org/fast/1039933
subject: Women--Economic conditions
valueUri: http://id.worldcat.org/fast/1176665
subject: Feminism
valueUri: http://id.worldcat.org/fast/922671

description: The newsletter of the Victoria chapter of Voice of Women. VOW is a women's organization founded in 1960 as a feminist group committed using a feminist approach to advocate for the abolition of nuclear weapons. Over the years, it has undertaken many initiatives to amplify women's voices in the pursuit of peace including the abolition of war and the promotion of non-violent means of conflict resolution, social justice and sustainability.
Ethiopian Field Epidemiology Training Program (EFETP) Compiled Body of Works in Field Epidemiology
Creators: name: Asnake, Abushet
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2014

description: Public Health Emergency Management (PHEM) is one of the core processes identified in Federal Ministry of Health. PHEM is the process of anticipating, preventing, preparing for, detecting, responding to, controlling, and recovering from the consequences of public health threats in order that health and economic impacts are minimized. PHEM is designed to ensure rapid detection of any public health threats, preparedness related to logistic and fund administration, and prompt response to and recovery from various public health emergencies, which range from recurrent epidemics, emerging infections, nutritional emergencies, chemical spills, and bioterrorism. The activities under this core process are to be implemented by appropriately trained and capable professionals. Since 2009 Ethiopia Field Epidemiology Training Program had been giving the program to contribute for trained and capable professionals. The Ethiopia Field Epidemiology Training Program is a two years and in service training program in the assigned field bases. The program is giving in collaboration. Addis Ababa University, School of public Health, Ethiopia Field Epidemiology Training Program, Federal Ministry of Health/Ethiopia Public Health Institute, Ethiopia Public Health Association with CDC Ethiopia and the Regional Health Bureau are executing the program. Field epidemiology Training Program has two components; a 25% class room teaching component and 75% practical or field placement component. During practical component residents assigned in the field base staying in the field base there are two residency out puts, which are residency I and residency II. During practical or field placement outbreak or epidemic investigation, desk review data analysis, description of health profile, writing a scientific manuscript for peer review journals, abstracts for scientific conferences, writing a protocol/proposal of epidemiologic research projects, narrative of a disaster situation or report on health and nutrition need assessment in visited woredas and also additional outputs like PHEM training are including in this document. In the Field base, the field supervisor is leading the whole activities throughout the academic years (two). The field base residency outputs are described in detail on the so called body of work. This body of work contains nine chapters.
Social and economic factors affecting trees on farms in the Upper Valley and Dandenong Ranges Region
Creators: name: Phūangsamlī., ʻAnuchāt
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Eris: Measuring discord among multidimensional data sources
Creators: name: Abello, Alberto
name: Cheney, James
Publisher: name: arXiv
Year: 2022
Subjects: subject: Databases (cs.DB)
subject: FOS: Computer and information sciences
subject: H.2.4
subject: 68P15

description: Data integration is a classical problem in databases, typically decomposed into schema matching, entity matching and data fusion. To solve the latter, it is mostly assumed that ground truth can be determined. However, in general, the data gathering processes in the different sources are imperfect and cannot provide an accurate merging of values. Thus, in the absence of ways to determine ground truth, it is important to at least quantify how far from being internally consistent a dataset is. Hence, we propose definitions of concordant data and define a discordance metric as a way of measuring disagreement to improve decision making based on trustworthiness. We define the discord measurement problem of numerical attributes in which given a set of uncertain raw observations or aggregate results (such as case/hospitalization/death data relevant to COVID-19) and information on the alignment of different conceptualizations of the same reality (e.g., granularities or units), we wish to assess whether the different sources are concordant, or if not, use the discordance metric to quantify how discordant they are. We also define a set of algebraic operators to describe the alignments of different data sources with correctness guarantees, together with two alternative relational database implementations that reduce the problem to linear or quadratic programming. These are evaluated against both COVID-19 and synthetic data, and our experimental results show that discordance measurement can be performed efficiently in realistic situations.
description: 33 pages, 15 figures
Exploring Selected Maternity Service Utilization among Homeless Mothers in Addis Ketema Sub-City, Addis Ababa, Ethiopia: Descriptive Phenomenological Qualitative Study
Creators: name: Azilke, Tamire
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2016

description: Background: - Homeless mothers who become pregnant are least prepared economically and emotionally to care for their infants. They usually lack gainful employment, as a result live in an unstable conditions and lead an economically hardship life. In addition, the problem to pregnant mothers is compounded by either lack of access or inadequate utilization of health care services before and during childbirth due to various factors. This study tried to address and understand the experiences of homeless mothers in relation to institutional delivery service utilization. Objective: - To explore the phenomena and experiences to selected maternity service utilization among homeless mothers who gave childbirth in the last 12 months in Addis Ketema Sub-city, Addis Ababa, Ethiopia. Methodology:-A descriptive qualitative phenomenological study was conducted among homeless mothers who gave childbirth in the last 12 months prior to the study and midwives working in Addis Ketema Sub-City health centers. In-depth interview was conducted with 25 homeless mothers mainly from and around churches and mosques. Time-location and purposive sampling technique were used to get homeless mothers. In-depth interview also was conducted with 5 midwives by using purposive sampling technique from the health centers located in Addis Ketema Sub-City of Addis Ababa City Administration. A semi structured questionnaire was used to collect data and the collected data and the in-depth interviews were tape-recorded, transcribed and then the transcripts were analyzed by using a thematic analysis method. The open code software version 3.4 was used for coding and categorization. Result: - Homeless mothers' experience showed that barriers to antenatal care and institutional delivery service utilization resulted from themes categorized as socio-economic, socio-cultural and cognitive reasons. The major barriers identified from these categories include lack of knowledge, priority for begging and house hold chores, lack of constant income, community negative beliefs and sense of insecurity. Conclusion and Recommendation: - An understanding of health care experiences from the homeless mothers' perspectives should guide the actions to address the cognitive, socio-cultural and socio-economic barriers
Expression of the protein phosphatases PP1a and PP1g1 in rat ascites hepatoma cell lines and in rat hepatocyte cell line
Creators: name: Kikuchi, Kunimi
name: Saadat, Mostafa
Publisher: name: Technische Universität Dortmund
Year: 2005
Subjects: subject: ascites hepatoma
subject: cell culture
subject: PP1a
subject: PP1g1
subject: protein phosphatase
subject: 610

description: Expressions of protein phosphatases 1a (PP1a), and 1g1 (PP1g1) was determined in cultured rat ascites hepatoma cell lines (AH-13, AH-109A) and in the normal rat hepatocyte cell line RLN-B2 by Northern blot analysis. High levels of PP1a mRNA expression were observed only in the hepatoma cells. In RLN-B2 cells only PP1g1 mRNA was increased compared to normal rat liver. In all cell types, mRNA levels of PP1g1 decreased as a function of harvest time. The present data show that PP1a mRNA is expressed at high levels in hepatoma cells in vivo, but rapidly decreased under critical nutritional conditions.
description: EXCLI Journal ; Vol. 4, 2005
Collective resonance fluorescence in small and dense atom clouds: Comparison between theory and experiment
Creators: name: Jenkins, S. D.
name: Ruostekoski, J.
name: Javanainen, J.
name: Jennewein, S.
name: Bourgain, R.
name: Pellegrino, J.
name: Sortais, Y. R. P.
name: Browaeys, A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the emergence of a collective optical response of a cold and dense $^{87}$Rb atomic cloud to a near-resonant low-intensity light when the atom number is gradually increased. Experimental observations are compared with microscopic stochastic simulations of recurrent scattering processes between the atoms that incorporate the atomic multilevel structure and the optical measurement setup. We analyze the optical response of an inhomogeneously-broadened gas and find that the experimental observations of the resonance line shifts and the total collected scattered light intensity in cold atom clouds substantially deviate from those of thermal atomic ensembles, indicating strong light-induced resonant dipole-dipole interactions between the atoms. At high densities, the simulations also predict a significantly slower decay of light-induced excitations in cold than in thermal atom clouds. The role of dipole-dipole interactions is discussed in terms of resonant coupling examples and the collective radiative excitation eigenmodes of the system.
Effect of quantum jumps on non-Hermitian system
Creators: name: Niu, Xiangyu
name: Li, Jianning
name: Wu, S. L.
name: Yi, X. X.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: One among the possible realizations of non-Hermitian systems is based on open quantum systems by omitting quantum jumping terms in the master equation. This is a good approximation at short times where the effects of quantum jumps can be ignored. However, the jumps can affect the long time dynamics of the system, motivating us to take the jumps into account in these studies. In this paper, by treating the quantum jumps as perturbations, we examine the effect of the quantum jumps on the non-Hermitian system. For this purpose, we first derive an effective Hamiltonian to describe the dynamics of the open quantum system based on the master equation, then expand the eigenstates and eigenenergies up to the first and second order in the quantum jumps. Finally, we apply our theory to a dissipative two-level system and dissipative fermionic superfluids. The effect of quantum jump on the dynamics and the nonequilibrium phase transition is demonstrated and discussed.
description: 9 pages,7 figures
Stage-specific expressions of four different ribonuclease H genes in Leishmania
Creators: name: Chaudhuri, Gautam
name: Farrow, Anitra L.
name: Misra, Smita
Publisher: name: Technische Universität Dortmund
Year: 2005
Subjects: subject: Amastigote
subject: Leishmania major
subject: Promastigotes
subject: Ribonuclease H
subject: Trypanosoma brucei
subject: Trypanosoma cruzi
subject: Upstream open reading frame
subject: 610

description: The human pathogen of the genus Leishmania cause worldwide morbidity and infection of visceral organs by some species may be lethal. Lack of rational chemotherapy against these pathogens dictates the study of differential biochemistry and molecular biology of the parasite as compared to its human host. The ubiquitous enzyme ribonuclease H (RNase H, EC 3.1.26.4) cleaves the RNA from a RNA:DNA duplex and is critical for the replication of DNA in the nucleus and the mitochondria. We have characterized four RNase H genes from Leishmania: one is of type I (LRNase HI) and three others are of type II (LRNase HIIA, -HIIB and -HIIC). In contrast human cells have only one type I and one type II RNase H. All the four RNase H genes in Leishmania are single copy and located in discrete chromosomes. When expressed inside RNase H-deficient E. coli, all of the four Leishmania RNase H were capable to complement the genetic defect of the E. coli, indicating their identity as RNase H. The enzymes are differentially expressed in the promastigotes and the amastigotes, the forms that thrives in entirely different physico-chemical conditions in nature. Nucleotide sequences of the 5'-UTRs of three of these mRNAs have upstream open reading frames. Understanding the regulation of these four distinct ribonuclease H genes in Leishmania will help us better understand leishmanial parasitism and may help us to design rational chemotherapy against the pathogen.
description: EXCLI Journal ; Vol. 4, 2005
Innovatie in de boekenketen
Creators: name: Hermans, Marianne
Publisher: name: Zenodo
Year: 2020
Subjects: innovatie
boekenvak
bibliotheken
lezen
leesgedrag

description: Digitalisering leidt tot verschuivingen in de traditionele waardeketen van auteur - uitgever - boekhandel en bibliotheek - lezer. De waardeketen is nu een flexibel netwerk met de klant als middelpunt. De rolverdeling tussen de verschillende partijen verandert en er komen nieuwe, branchevreemde toetreders op de markt. Auteurs zijn zelf uitgever, lezers gaan zelf publiceren, online platforms maken bemiddelaars ten dele overbodig. Daardoor gaan verdienmodellen en bestaande structuren op de schop en komen er nichemarkten bij. Ook groeit het aanbod van streamingdiensten, die beter aansluiten bij de manier waarop mensen hun vrije mediatijd willen besteden.
description: Dit artikel was onderdeel van Dossier Trends, geschreven in opdracht van de Koninklijke Bibliotheek, 2019
An assessment of land evaluation methods for recreational land use
Creators: name: Lewis, Barry.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Lexikalisches und grammatisches Material
Creators: name: Breder, Wilhelm
name: Doherty, Timothy J. G.
name: Hauss, Michael
Publisher: name: Zeitschrift für Althebraistik
Year: 1970

description: Zeitschrift für Althebraistik, Bd. 2 Nr. 2 (1989): Zeitschrift für Althebraistik, Band 2, Heft 2
A Neural Network Gravitational Arc Finder based on the Mediatrix filamentation Method
Creators: name: Bom, C. R.
name: Makler, M.
name: Albuquerque, M. P.
name: Brandt, C. H.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Automated arc detection methods are needed to scan the ongoing and next-generation wide-field imaging surveys, which are expected to contain thousands of strong lensing systems. Arc finders are also required for a quantitative comparison between predictions and observations of arc abundance. Several algorithms have been proposed to this end, but machine learning methods have remained as a relatively unexplored step in the arc finding process. In this work we introduce a new arc finder based on pattern recognition, which uses a set of morphological measurements derived from the Mediatrix Filamentation Method as entries to an Artificial Neural Network (ANN). We show a full example of the application of the arc finder, first training and validating the ANN on simulated arcs and then applying the code on four Hubble Space Telescope (HST) images of strong lensing systems. The simulated arcs use simple prescriptions for the lens and the source, while mimicking HST observational conditions. We also consider a sample of objects from HST images with no arcs in the training of the ANN classification. We use the training and validation process to determine a suitable set of ANN configurations, including the combination of inputs from the Mediatrix method, so as to maximize the completeness while keeping the false positives low. In the simulations the method was able to achieve a completeness of about 90% with respect to the arcs that are input to the ANN after a preselection. However, this completeness drops to $\sim$ 70% on the HST images. The false detections are of the order of 3% of the objects detected in these images. The combination of Mediatrix measurements with an ANN is a promising tool for the pattern recognition phase of arc finding. More realistic simulations and a larger set of real systems are needed for a better training and assessment of the efficiency of the method.
description: Updated to match published version
Expression of interleukin-4, interleukin-9 and interleukin-13 in peripheral blood mononuclear cells of cystic fibrosis patients with and without allergy
Creators: name: Daigneault, Patrick
name: Hamid, Qutayba
name: Hauber, Hans-Peter
name: Matouk, Elias
name: Paque, France
Publisher: name: Technische Universität Dortmund
Year: 2006
Subjects: subject: allergy
subject: cystic fibrosis
subject: cytokine
subject: interleukin
subject: lymphocyte
subject: monocyte
subject: 610

description: Bronchial hyperresponsiveness (BHR) and mucus overproduction are common in CF pulmonary disease and allergic reactions can be frequently observed in cystic fibrosis (CF) lung disease. However, the underlying pathophysiological mechanisms are far from being completely understood. Therefore the expression of the Th2 type cytokines interleukin (IL)-4, IL-9 and IL-13 in CF patients with allergy was compared to patients without allergy. Peripheral blood mononuclear cells (PBMC) samples from 9 allergic CF patients and 8 non-allergic CF patients were obtained. In situ hybridization and immunocytochemistry were performed to determine mRNA and protein expression of IL-4, IL-9, and IL-13 in PBMC. PBMC from allergic CF patients expressed significantly more IL-13 mRNA and protein compared to non-allergic patients (p < 0.05). There was no significant difference for IL-4 and IL-9 between the two groups. In both groups IL-9 mRNA and protein expression were significantly higher compared to IL-4 and IL-13 expression (p < 0.05). These results suggest that IL-13 plays an important role in allergic disease in CF. Moreover, IL-9 may be important in CF disease whether allergy is present or not as it may contribute to BHR and mucus overproduction.
description: EXCLI Journal ; Vol. 5, 2006
Communication influences on US Black Women’s Pregnancy Risk Perceptions and Related Behavioral Responses
Creators: name: Adekunle, Tiwaladeoluwa
Publisher: name: Purdue University Graduate School
Year: 2023
Subjects: Communication studies

description: Pregnancy poses unjust dangers to Black women in the United States, who are currently faced with higher rates of maternal mortality and pregnancy-related adverse events than women of other races. The maternal mortality ratio for non-Hispanic Black women is 41.4/100,000 compared with 13.7/100,000 for White women (Hill et al., 2022). Although there are available statistics and other forms on expert knowledge on these dangers, risk perceptions and related behaviors are derived from subjective individual interpretations within a dynamic communicative context. While there is extensive evidence on the dangers pregnancy and childbirth pose to Black women, less is known about Black women’s conceptualizations of their own risks, the role of communication (with their healthcare providers and other sources), and the ways in which they enact agency in response to these risks. Using a multi-methodological approach that draws on in-depth interviews, qualitative network analysis and an environmental scan, this dissertation foregrounds Black women’s own narratives to explore the social construction of pregnancy risk, the role of communication with healthcare providers in the amplification or attenuation of these risks, and the broader communicative context that shapes Black women’s pregnancy experiences. In doing so, this study found that Black women’s pregnancy risk perceptions are socially constructed through communication in a socio-political context shaped by gendered racism, and Black women enacted agency in response to these risks in a variety of ways constrained by gendered racism, including intentional decision-making, extensive research, and self-advocacy. Insights from in-depth interviews and the qualitative network analysis were contextualized in an environmental scan that included a review of relevant policies, interviews with community leaders, and a review of community organizations efforts to support Black women. This dissertation concludes with a discussion of contributions to theory and insights for Black women, healthcare providers, community organizations, media and policy makers.
Manganese inactivation of renal betaine aldehyde dehydrogenase from swine
Creators: name: Figueroa-Soto, Ciria G.
name: Ruíz-López, Judith C.
name: Valenzuela-Soto, Elisa M.
Publisher: name: Technische Universität Dortmund
Year: 2006
Subjects: subject: betaine aldehyde dehydrogenase
subject: fuel pollution
subject: glycine betaine
subject: manganese
subject: renal osmoregulation
subject: 610

description: Manganese is an essential micronutrient for mammals, however high manganese concentrations cause adverse health effects. Swine renal betaine aldehyde dehydrogenase catalyzes the synthesis of glycine betaine, which plays an important role in renal cells osmoregulation. In vitro inactivation of BADH was observed by incubating the purified enzyme in the presence of 1 mM MnCl2 under physiological and low ionic strength conditions. Enzyme inactivation followed first order kinetics in a monophasic process with an inactivation constant of 0.126 ± 0.011 min^-1 and 0.137 ± 0.017 at physiological and low ionic strength, respectively. Enzyme inactivation was not prevented by physiological ionic strength, nor by the substrates NAD+ and betaine aldehyde at saturated concentrations. The enzyme was reactivated with DTT and GSH. Native-PAGE of the inactivated enzyme showed no change in the tetrameric conformation. Intrinsic protein fluorescence studies demonstrated an increased exposure of the tryptophan residues to the aqueous solvent when the enzyme was incubated with Mn^2+. These results suggest that BADH inactivation by Mn^2+ may result from the oxidation of cysteines, which induces changes in the tertiary structure of the enzyme.
description: EXCLI Journal ; Vol. 5, 2006
Perspectives of microwave quantum key distribution in open-air
Creators: name: Fesquet, Florian
name: Kronowetter, Fabian
name: Renger, Michael
name: Chen, Qiming
name: Honasoge, Kedar
name: Gargiulo, Oscar
name: Nojiri, Yuki
name: Marx, Achim
name: Deppe, Frank
name: Gross, Rudolf
name: Fedorov, Kirill G.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: One of the cornerstones of quantum communication is the unconditionally secure distribution of classical keys between remote parties. This key feature of quantum technology is based on the quantum properties of propagating electromagnetic waves, such as entanglement, or the no-cloning theorem. However, these quantum resources are known to be susceptible to noise and losses, which are omnipresent in open-air communication scenarios. In this work, we theoretically investigate the perspectives of continuous-variable open-air quantum key distribution at microwave frequencies. In particular, we present a model describing the coupling of propagating microwaves with a noisy environment. Using a protocol based on displaced squeezed states, we demonstrate that continuous-variable quantum key distribution with propagating microwaves can be unconditionally secure at room temperature up to distances of around 200 meters. Moreover, we show that microwaves can potentially outperform conventional quantum key distribution at telecom wavelength at imperfect weather conditions.
description: 13 pages, 6 figures
Victoria Voice of Women (Spring, 1990)
Creators: name: Voice Of Women (Association)
Publisher: name: University of Victoria Libraries
Year: 2022
Subjects: subject: Women's rights
valueUri: http://id.worldcat.org/fast/1178818
subject: Sex discrimination against women
valueUri: http://id.worldcat.org/fast/1114376
subject: Nuclear disarmament
valueUri: http://id.worldcat.org/fast/1039933
subject: Women--Legal status, laws, etc.
valueUri: http://id.worldcat.org/fast/1176824
subject: Women--Social conditions
valueUri: http://id.worldcat.org/fast/1176947
subject: Women--Economic conditions
valueUri: http://id.worldcat.org/fast/1176665
subject: Women and war
valueUri: http://id.worldcat.org/fast/1177123
subject: Women--Societies and clubs
valueUri: http://id.worldcat.org/fast/1176970
subject: Feminism
valueUri: http://id.worldcat.org/fast/922671

description: The newsletter of the Victoria chapter of Voice of Women. VOW is a women's organization founded in 1960 as a feminist group committed using a feminist approach to advocate for the abolition of nuclear weapons. Over the years, it has undertaken many initiatives to amplify women's voices in the pursuit of peace including the abolition of war and the promotion of non-violent means of conflict resolution, social justice and sustainability.
title: Appropriate Technology for the Bioconversion of Water Hyacinth (Eichhornia crassipes) to Liquid Ethanol
title: Future Prospects for Community Strengthening and Sustainable Development
titleType: AlternativeTitle
Creators: name: Isarankura-Na-Ayudhya, Chartchalerm
name: Kongpanpee, Thikamporn
name: Prabkate, Ponpitak
name: Prachayasittikul, Virapong
name: Tantimongcolwat, Tanawut
Publisher: name: Technische Universität Dortmund
Year: 2007
Subjects: subject: acid hydrolysis
subject: bioconversion
subject: bioenergyCandida shehatae
subject: ethanol
subject: fermentation
subject: water hyacinth
subject: 610

description: This article appraises the need for introducing appropriate technology to improve the production of renewable energy, particularly on the community basis and social aspect of sustainability. Using two-sequential steps of acid hydrolysis (10% sulfuric acid) and yeast (Candida shehatae; xylose-fermenting yeast) fermentation, bioconversion of water hyacinth (Eichhornia crassipes; a noxious weed and fast growing aquatic plant widely distributed in many tropical regions of the world) to liquid ethanol has successfully been performed. The maximum ethanol yield coefficient of 0.19 g g-1 WH with the productivity of 0.008 g l-1 h-1 was achieved. This is as well comparable to those obtained from the enzymatic saccharification and/or the fermentation of acid-pretreated water hyacinth hydrolysate using fully-equipped fermenter reported elsewhere. More importantly, determinations of xylose and ethanol contents can potentially be performed using two reliable colorimetric approaches (Phloroglucinol and Dichromate assays, respectively) in conjunction with home-made portable photometer. The technology presented herein can be transferred and implemented to gain opportunity of becoming self-reliance of community in the third world countries.
description: EXCLI Journal ; Vol. 6, 2007
Elastic scattering, polarization and absorption of relativistic antiprotons on nuclei
Creators: name: Larionov, A. B.
name: Lenske, H.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We perform Glauber model calculations of the antiproton-nucleus elastic and quasielastic scattering and absorption in the beam momentum range $\sim 0.5\div10$ GeV/c. A good agreement of our calculations with available LEAR data and with earlier Glauber model studies of the $\bar p A$ elastic scattering allows us to make predictions at the beam momenta of $\sim 10$ GeV/c, i.e. at the regime of the PANDA experiment at FAIR. The comparison with the proton-nucleus elastic scattering cross sections shows that the diffractive minima are much deeper in the $\bar p A$ case due to smaller absolute value of the ratio of the real-to-imaginary part of the elementary elastic amplitude. Significant polarization signal for $\bar p A$ elastic scattering at 10 GeV/c is expected. We have also revealed a strong dependence of the $\bar p A$ absorption cross section on the slope parameter of the transverse momentum dependence of the elementary $\bar pN$ amplitude. The $\bar p A$ optical potential is discussed.
description: 36 pages, 14 figures, minor revisions, results unchanged, version accepted in Nucl. Phys. A
Encoding trade-offs and design toolkits in quantum algorithms for discrete optimization: coloring, routing, scheduling, and other problems
Creators: name: Sawaya, Nicolas PD
name: Schmitz, Albert T
name: Hadfield, Stuart
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Challenging combinatorial optimization problems are ubiquitous in science and engineering. Several quantum methods for optimization have recently been developed, in different settings including both exact and approximate solvers. Addressing this field of research, this manuscript has three distinct purposes. First, we present an intuitive method for synthesizing and analyzing discrete (i.e., integer-based) optimization problems, wherein the problem and corresponding algorithmic primitives are expressed using a discrete quantum intermediate representation (DQIR) that is encoding-independent. This compact representation often allows for more efficient problem compilation, automated analyses of different encoding choices, easier interpretability, more complex runtime procedures, and richer programmability, as compared to previous approaches, which we demonstrate with a number of examples. Second, we perform numerical studies comparing several qubit encodings; the results exhibit a number of preliminary trends that help guide the choice of encoding for a particular set of hardware and a particular problem and algorithm. Our study includes problems related to graph coloring, the traveling salesperson problem, factory/machine scheduling, financial portfolio rebalancing, and integer linear programming. Third, we design low-depth graph-derived partial mixers (GDPMs) up to 16-level quantum variables, demonstrating that compact (binary) encodings are more amenable to QAOA than previously understood. We expect this toolkit of programming abstractions and low-level building blocks to aid in designing quantum algorithms for discrete combinatorial problems.
description: 48 pages; 11 figures; Accepted to Quantum Journal
The human influence on the fire regimes of the Upper Delegate River, East Gippsland, Victoria
Creators: name: Stuart, Iain-Malcolm F.
Publisher: name: Monash University
Year: 2022

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
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