cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anti-food and anti-microbial IgG subclass antibodies in inflammatory bowel disease
Creators: name: Jansen, Anke
name: Mandić, Ana D.
name: Bennek, Eveline
name: Frehn, Lisa
name: Verdier, Julien
name: Tebrügge, Irene
name: Lutz, Holger
name: Streetz, Konrad
name: Trautwein, Christian
name: Sellge, Gernot
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Objectives: Inflammatory bowel disease (IBD), particularly Crohn’s disease (CD), is associated with increased microbial-specific IgG and IgA antibodies, whereas alterations of anti-food antibodies are still disputed. The knowledge about IgG subclass antibodies in IBD is limited. In this study we analysed IgG subclass antibodies specific for nutritional and commensal antigens in IBD patients and controls. Methods: Serum IgG1, IgG2, IgG3 and IgG4 specific for wheat and milk extracts, purified ovalbumin, Escherichia coli and Bacteroides fragilis lysates and mannan from Saccharomyces cerevisiae were analysed by ELISA in patients with CD (n = 56), ulcerative colitis (UC; n = 29), acute gastroenteritis/colitis (n = 12) as well as non-inflammatory controls (n = 62). Results: Anti-Saccharomyces cerevisiae antibodies (ASCA) of all IgG subclasses and anti-B. fragilis IgG1 levels were increased in CD patients compared to UC patients and controls. The discriminant validity of ASCA IgG2 and IgG4 was comparable with that of ASCA pan-IgG and IgA, whereas it was inferior for ASCA IgG1/IgG3 and anti-B. fragilis IgG1. Complicated CD defined by the presence of perianal, stricturing or penetrating disease phenotypes was associated with increased ASCA IgG1/IgG3/IgG4, anti-B. fragilis IgG1 and anti-E. coli IgG1 levels. Anti-food IgG subclass levels were not different between IBD patients and controls and did not correlate with food intolerance. In contrast to anti-microbial Abs, food-specific IgG responses were predominately of the IgG4 isotype and all food-specific IgG subclass levels correlated negatively with age. Conclusion: Our study supports the notion that the adaptive immune recognition of food and commensal antigens are differentially regulated.
DeepAutoMapping: low-cost approach to geospatial data generation using deep learning and a monocular camera
Creators: name: Al-Azizi, Jalal
name: Shafri, Helmi Zulhaidi Mohd
name: Shaiful Jahari Bin Hashim
name: Shattri B Mansor
Publisher: name: figshare
Year: 2020
Subjects: subject: 90903 Geospatial Information Systems
subject: FOS: Environmental engineering

description: low-cost prototype solution based on deep learning and geospatial technology called DeepAutoMapping
title: Liste de mots en chrau lue par une locutrice née à Vinh Thanh en 1964
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chrau
subject: crw

description: Social Sciences and humanities Research Council of Canada 435-2017-0498: Voicing and its transphonologization: the initiation and actuation of a sound change in Southeast Asia. Frame sentences containings target words with onset dentals and velars.
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Characteristics and behaviour of brushtail possums initially moving into a depopulated area
Creators: name: P Cowan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Plant Biology

description: Brushtail possums are controlled extensively in New Zealand because they are a livestock disease vector and have an impact on native biodiversity. Reinvasion of controlled areas and subsequent population recovery is a significant management problem but little attention has been paid to what influences the settlement of possums in depopulated areas. To address this gap we trapped possums out of an area of about 24 ha in native podocarp–hardwood forest and studied reinvasion and settlement in the central c. 14 ha over 22 months. Most new possums were young males, but adults were also trapped. Many of the new possums caught on the study site post-depopulation did not settle there, most likely because they continued to disperse, but some may have returned to their ranges nearby or were residents with a very low probability of capture. This finding highlights the need for better information about the origins and settlement of possums in depopulated areas to improve management of population recovery and long-term sustained control of possums.
Supplementary Appendix from The propagation of admixture-derived adaptive radiation potential
Creators: name: Kagawa, Kotaro
name: Seehausen, Ole
Publisher: name: The Royal Society
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Ecology

description: This file contains the following: Appendix S1-4: Supplementary methods and results, Appendix S5: Supplementary discussion, Table S1: List of model parametres, and Supplementary Figures S1-14
Brief Assessment of Parental Perception (BAPP): Development and validation of a new measure for assessing paediatric outcomes after bilateral cochlear implantation
Creators: name: V. Samuel
name: C. Gamble
name: H. Cullington
name: F. Bathgate
name: E. Bennett
name: N. Coop
name: J. Cropper
name: A. Emond
name: R. Kentish
name: L. Edwards
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Objective: In contrast to previous clinical practice, current guidelines recommend bilateral cochlear implantation in children, resulting in a cohort of children who initially received one implant, but have subsequently had a second, contralateral implant. This study aimed to explore satisfaction and quality of life in children implanted simultaneously or sequentially. Design: A novel measure of satisfaction and quality of life following paediatric bilateral cochlear implantation (the Brief Assessment of Parental Perception; BAPP) was developed and preliminary validation undertaken as part of a large, national project of bilateral implantation. Children’s parents completed the measure yearly for up to three years following implantation. Study sample: Children from 14 UK implant centres were recruited into the study; data were available for 410 children one year post-implantation. Results: The BAPP was found to have good face and convergent validity, and internal consistency. Results indicated very high levels of satisfaction with the devices, and improvements in quality of life. However there was evidence that children implanted sequentially were less willing to wear their second implant in the first two years than those children receiving simultaneous implants. Conclusion: Simultaneous and sequential cochlear implants have a positive impact on the quality of life of deaf children.
Pomiar_sprawnosci_dzialania_w_zwinnych_m.pdf
Creators: name: Woźniak, Krzysztof
Publisher: name: figshare
Year: 2016
Subjects: subject: 150399 Business and Management not elsewhere classified
subject: FOS: Economics and business

description: The paper presents theoretical and methodological considerations in matters of efficiency in software project development teams which use agile methodologies. In the contemporary literature, those methodologies are described as a universal solution to all organisational problems faced by managers of large teams working on complex IT
projects.

This article attempts to answer the question of the extent to which agile software development methodologies fulfill the conditions of the classical methodological efficiency. I suggest that even when using agile design methodology, managers should attempt to operationalise the basic parameters describing the efficiency and effectiveness
of the team. This will allow them to make effective decisions based on facts, not assumptions and hunches.
SCP Journal - "Software architecture decision-making process: the practitioners' view from the Brazilian industry" - Interview guide versions
Creators: name: Carvalho, Lucas
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 461206
subject: Software architecture

description: Supplementary material for the paper "Software architecture decision-making process: the practitioners' view from the Brazilian industry" submitted to the Science of Computer Programming Journal.
Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells
Creators: name: Haishan Huang
name: Junlan Zhu
name: Li, Yang
name: Liping Zhang
name: Jiayan Gu
name: Qipeng Xie
name: Honglei Jin
name: Che, Xun
name: Jingxia Li
name: Huang, Chao
name: Lung-Chi Chen
name: Jianxin Lyu
name: Jimin Gao
name: Chuanshu Huang
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Chronic lung inflammation is accepted as being associated with the development of lung cancer caused by nickel exposure. Therefore, identifying the molecular mechanisms that lead to a nickel-induced sustained inflammatory microenvironment that causes transformation of human bronchial epithelial cells is of high significance. In the current studies, we identified SQSTM1/p62 as a novel nickel-upregulated protein that is important for nickel-induced inflammatory TNF expression, subsequently resulting in transformation of human bronchial epithelial cells. We found that nickel exposure induced SQSTM1 protein upregulation in human lung epithelial cells in vitro and in mouse lung tissues in vivo. The SQSTM1 upregulation was also observed in human lung squamous cell carcinoma. Further studies revealed that the knockdown of SQSTM1 expression dramatically inhibited transformation of human lung epithelial cells upon chronic nickel exposure, whereas ectopic expression of SQSTM1 promoted such transformation. Mechanistic studies showed that the SQSTM1 upregulation by nickel was the compromised result of upregulating SQSTM1 mRNA transcription and promoting SQSTM1 protein degradation. We demonstrated that nickel-initiated SQSTM1 protein degradation is mediated by macroautophagy/autophagy via an MTOR-ULK1-BECN1 axis, whereas RELA is important for SQSTM1 transcriptional upregulation following nickel exposure. Furthermore, SQSTM1 upregulation exhibited its promotion of nickel-induced cell transformation through exerting an impetus for nickel-induced inflammatory TNF mRNA stability. Consistently, the MTOR-ULK1-BECN1 autophagic cascade acted as an inhibitory effect on nickel-induced TNF expression and cell transformation. Collectively, our results demonstrate a novel SQSTM1 regulatory network that promotes a nickel-induced tumorigenic effect in human bronchial epithelial cells, which is negatively controlled by an autophagic cascade following nickel exposure.
Field-Work in Cambridgeshire: April 96-July 97
Creators: name: Evans, Christopher
name: Lucas, Gavin
name: Malim, Tim
name: Reynolds, Tim
name: Way, Twigs
Publisher: name: Archaeology Data Service
Year: 2006

description: Proceedings of the Cambridge Antiquarian Society, 85, 171-188
description: Brief, separately authored summaries of fieldwork undertaken in Cambridgeshire between April 1996 and July 1997; arranged alphabetically by town or parish.
An Iron Age Square Barrow at Diddington, Cambridgeshire. Third Interim Report of excavations at Little Paxton Quarries: 1996.
Creators: name: Jones, Alex
Publisher: name: Archaeology Data Service
Year: 2002

description: Proceedings of the Cambridge Antiquarian Society, 86, 5-12
description: Noted as part of a larger programme of excavation which will attempt to determine the economy and function of the area and contribute to wider studies on the settlement of river valley environments. Flints and pottery from the Neolithic and Bronze Ages respectively were uncovered but the main focus was the rectangular shaped barrow or enclosure surrounded by a ditch. There is no evidence for inhumation and the presence of an entrance causeway could indicate a more domestic function for the structure but it has been interpreted as a square barrow of Arras type. There are separate sections on: `Flint' by Lynne Bevan (9); and `Pottery' by Ann Woodward (9).
title: Liste de mots en chrau lue par une locutrice née à Vinh Thanh en 1961
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chrau
subject: crw

description: Social Sciences and humanities Research Council of Canada 435-2017-0498: Voicing and its transphonologization: the initiation and actuation of a sound change in Southeast Asia. Frame sentences containings target words with onset dentals and velars.
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Impact of wheelchair seat height on neck and shoulder range of motion during functional task performance
Creators: name: Sabari, Joyce
name: Shea, Mary
name: Chen, Linda
name: Laurenceau, Alyssa
name: Leung, Evan
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Developmental Biology
subject: Cancer

description: Wheelchair users are at high risk for developing repetitive stress injuries (RSI) of the cervical spine and glenohumeral joints due to increased demands on active range of motion (AROM) when performing functional tasks from a seated position. The addition of a seat elevation device may alleviate the risk factors that lead to the development of RSI. However, there are no studies which establish that wheelchair seat height impacts upon arthrokinematic requirements at vulnerable joints. Additionally, Medicare and most insurance carriers do not cover the cost of power seat elevators because this feature has not been shown to be a “medical necessity.” This study examined differences in AROM at the cervical spine and glenohumeral joint during performance of two functional tasks while seated in a wheelchair with the seat elevation feature at minimum and maximum height. Results revealed statistically significant differences in AROM requirements for cervical extension and shoulder abduction between the two wheelchair seat heights. These findings provide preliminary support for the value of the power seat elevation function in minimizing the risk of RSI at the shoulder complex and cervical spine in wheelchair users.
A reappraisal of the evidence for the 'northern arm' of the Fleam Dyke at Fen Ditton
Creators: name: Kenney, Scott
Publisher: name: Archaeology Data Service
Year: 2010

description: Proceedings of the Cambridge Antiquarian Society, 98, 69-72
description: Reports that, while ditches were observed during evaluations, they were eighteenth century in date and no archaeology earlier than the medieval period was uncovered. This is argued to contradict the idea that the postulated northern arm of Fleam Dyke crosses the site (as is depicted on Ordnance Survey maps).
Late Holocene evolution of glaciers in the southeastern Alps
Creators: name: Colucci, Renato R.
name: Žebre, Manja
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Computational Biology

description: The Julian Alps (in the southeastern European Alps, Italy and Slovenia) represent an important case study area for the study of small and very small maritime glaciers. High mean annual precipitation results in great snow accumulation during the winter, permitting the presence of ice bodies with the lowest Equilibrium Line Altitudes in the Alps. During the Little Ice Age (LIA) 19 small glaciers (<1 km2) existed, covering a total area of 2.4 km2. By 2012, the glacierized area had shrunk by 84% and only isolated glacierets and ice patches survived, each having a total area less than 0.5 km2. We present here a geomorphological and palaeoglaciological map of 8 sections of the Julian Alps related to the late Holocene distribution of glaciers, at a scale of 1:6000. Glacier topography during the LIA maximum was reconstructed on the basis of well-expressed geomorphological features together with historical archive data. The present-day distribution of ice bodies was inferred from orthophotos and 1 m resolution digital terrain models derived from airborne laser scanning. The past and present areal extent and surface morphology of glaciers permits calculation of volume loss since the LIA, which is estimated at 96%.
DANUBIUS-RI institutions present in multiple RIs – status of the DANUBIUS-RI components in the context of the European research infrastructures
Creators: name: Madon, Bénédicte
Publisher: name: Zenodo
Year: 2024
Subjects: data interoperability

description: This deliverable contains the results from a first set of an internal landscape analysis to ensure compatibility of DANUBIUS-RI with other RIs and a use case on the contribution of CNR-ISMAR to the I-STORMS project in terms of solving interoperability challenges.
Synthesis, structural and spectroscopic studies of 1-(2-FUROYL)-3-phenylthiourea: a theoretical and experimental approach
Creators: name: Estévez-Hernández, Osvaldo
name: Salomón, Fernando F.
name: Duque, Julio
name: Joelis Rodríguez-Hernández
name: Gil, Diego M.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Hematology
subject: 60506 Virology
subject: FOS: Biological sciences

description: The thiourea derivative 1-(2-Furoyl)-3-phenylthiourea (FPT) was synthesized and characterized by using spectroscopic (IR, Raman, UV–VIS, 1H and 13C NMR) and structural methods (powder X-ray diffraction data). The experimental measurements were complemented with quantum chemical calculations. FPT crystallizes in the monoclinic crystal system, space group P21/c, with cell parameters a = 4.7679(5) Å, b = 20.9704(2) Å, c = 12.5109(5) Å and β = 109.811(10)°, V = 1176.87(3) Å3. In the crystal structure, the thiourea group makes dihedral angle of 43.8(5)° with the furoyl group, whereas the benzene ring is inclined by 24.3(4)°. The anti-syn geometry of the thiourea unit is stabilized by intramolecular N–H … O hydrogen bond between the H atom of the syn thioamide and the carbonyl O atom. In the crystal structure, molecules of FPT are packed through N–H···S, C–H···O and C–H···C hydrogen bonds, and a π–π interaction with offset arrangement. Hirshfeld surface analysis was performed in order to evaluate and quantify intermolecular interactions. The Hirshfeld surface analysis indicated that the H···H interactions comprise the majority of interactions. Shape index and curvedness clearly indicate π–π interactions in the compound FPT.
Rural Severances: Challenges & Opportunities for Landscape Productivity in Prince Edward County
Creators: name: Alton, Christopher
name: Cudmore, Jaimie
name: Lister, Nina-Marie
Publisher: name: figshare
Year: 2022
Subjects: subject: 160404 Urban and Regional Studies (excl. Planning)
subject: FOS: Social and economic geography

description: This paper serves as a broad literature review to give an introduction into the impact of land fragmentation from rural land severances, a common problem in many rural communities across North America and in particular, on the rise in Prince Edward County
Syntheses and characterization of the vanadium trimer (V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6(4,4′-bipyridine) and the vanadium hexamer [(V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6]2(μ2-N1,N2
Creators: name: Maass, John S.
name: Zhichao Chen
name: Zeller, Matthias
name: Luck, Rudy L.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Reacting VO(acac)2 with six equivalents of dibenzylphosphinic acid in the presence of 4,4′-bipyridine or μ2-N1,N2-di(pyridin-4-yl)oxalamide leads to trimeric (V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6(4,4′-bipyridine) or the hexamer [(V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6]2(μ2-N1,N2-di(pyridin-4-yl)oxalamide). The complexes were characterized by spectroscopic (FTIR and 1H NMR spectroscopies), TGA, and by single crystal X-ray diffraction measurements. The structures consist of a planar central core where three vanadium ions are arranged in the form of a quasi-isosceles triangle and contain an interstitial O which is multiply bonded to one V and weakly interacting at different bond distances to the remaining two V ions.
Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay
Creators: name: Inami, Keiko
name: Mine, Yusuke
name: Kojo, Yukiko
name: Tanaka, Satomi
name: Ishikawa, Satoko
name: Mochizuki, Masataka
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Antimutagenesis against N-nitroso compounds contribute to prevention of human cancer. We have found that Glycyrrhiza aspera ethanolic extract exhibits antimutagenic activity against N-methyl-N-nitrosourea (MNU) using the Ames assay with Salmonella typhimurium TA1535. In the present study, eight purified components from Glycyrrhiza, namely glabridin, glycyrrhetinic acid, glycyrrhizin, licochalcone A, licoricesaponin H2, licoricesaponin G2, liquiritigenin and liquiritin were evaluated for their antimutagenicity against MNU in the Ames assay with S. typhimurium TA1535. Glycyrrhetinic acid, glycyrrhizin, licoricesaponin G2, licoricesaponin H2 and liquiritin did not show the antimutagenicity against MNU in S. typhimurium TA1535. Glabridin, licochalcone A and liquiritigenin reduced revertant colonies derived from MNU in S. typhimurium TA1535 without showing cytotoxic effects, indicating that these compounds possess antimutagenic activity against MNU. The inhibitory activity of glabridin and licochalcone A was more effective than that of liquiritigenin. Thus, Glycyrrhiza contains antimutagenic components against DNA alkylating, direct-acting carcinogens.
OCTET Trial Statistical Analysis Plan
Creators: name: Roberts, Chris
name: O'Leary, Neil
Publisher: name: figshare
Year: 2016
Subjects: subject: Clinical Psychology
subject: 111005 Mental Health Nursing
subject: FOS: Health sciences
subject: 111714 Mental Health

description: Scientific title Obsessive Compulsive Treatment Efficacy Trial (OCTET) Acronym OCTETISRCTN RegistrationISRCTN73535163 DOI 10.1186/ISRCTN73535163 Study hypothesis 1. Identify and confirm estimated recruitment rates for an obsessive compulsive disorder (OCD) treatment trial via an internal pilot phase aimed at evaluating recruitment rates and primary outcome point
 2. Proceed seamlessly to a full RCT (if recruitment is successful in the pilot phase) to determine:
 2.1. The clinical and cost-effectiveness of two self-managed CBT interventions (cCBT and bibliotherapy) compared to a CBT waiting list in the management of OCD patients in the short term at 3- and 6-month follow-up
 2.2. The clinical and cost-effectiveness of self-managed therapies plus conventional CBT compared to waiting list plus conventional CBT at 12-month follow-up
 3. Determine patient compliance and patient and health professional acceptability of the two self-managed therapy packages (cCBT & GSH)

 More details can be found at http://www.nets.nihr.ac.uk/projects/hta/098101
 Protocol can be found at http://www.nets.nihr.ac.uk/__data/assets/pdf_file/0006/54699/PRO-09-81-01.pd
title: Liste de mots en chrau lue par une locutrice née à Vinh Thanh en 1990
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chrau
subject: crw

description: Social Sciences and humanities Research Council of Canada 435-2017-0498: Voicing and its transphonologization: the initiation and actuation of a sound change in Southeast Asia. Frame sentences containings target words with onset dentals and velars.
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Antiproliferative activity of Juglone derivatives on rat glioma
Creators: name: Pavan, Valeria
name: Ribaudo, Giovanni
name: Zorzan, Maira
name: Redaelli, Marco
name: Pezzani, Raffaele
name: Mucignat-Caretta, Carla
name: Zagotto, Giuseppe
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Malignant gliomas are aggressive and life-threatening tumours that still show a poor prognosis: the current therapeutic approach based on surgical resection and chemotherapy combined with radiotherapy does not provide a satisfactory chance of long-term survival to patients. Natural bioactive compounds represent a precious source of molecules with antiproliferative activity, potentially effective also against glioma cells. Among these, Juglone is a known allelopathic compound extracted from the eastern black walnut (Juglans nigra) whose antimitotic effect has been extensively described in mammalian cells. We investigated the antiproliferative effect of a synthetic derivative of this natural compound, 2-(2,4-dihydroxyphenyl)-8-hydroxy-1,4-naphthoquinone (DiNAF), in rat glioma cells. We compared this molecule and its effect with the natural reference compound and with newly synthesised derivatives to build a preliminar structure–activity relationship. Biological assays and NMR-based redox experiments confirmed that DiNAF is a promising lead and supported the hypothesis of a redox mechanism underlying its cytotoxic activity.
Chemical composition of the essential oil from carnation coniferous (Dianthus acicularis Fisch. ex Ledeb) growing wild in Northern Kazakhstan
Creators: name: Kirillov, Vitaliy
name: Stikhareva, Tamara
name: Suleimen, Yerlan
name: Serafimovich, Mariya
name: Kabanova, Svetlana
name: Mukanov, Bolat
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: The aim of the study was to investigate volatile compounds from the aerial parts of Dianthus acicularis of the genus Dianthus of the family Caryophyllaceae grown wild in Northern Kazakhstan for the first time. D. acicularis is a typical Trans-Volga-Kazakhstani endemic. D. acicularis has high resistance to the bacterial wilt, a serious disease caused by Burkholderia caryophylli. The qualitative and quantitative compositions of the specimens of the essential oils were analysed by the method of GC–MS. The main constituents of D. acicularis essential oil were methyl ketones - 2-pentadecanone (26.9–32.2%) and 2-tridecanone (4.7–17.7%), identified for the first time in the Dianthus genus. The methyl ketone activity provides protection of the plants from herbivores and fungal pathogens. One can suppose that the presence of 2-pentadecanone and 2-tridecanone in the essential oil of carnation coniferous provides its resistance to different insects and pathogens, including the resistance to the bacterial wilt.
Prehistoric and Roman remains at Edix Hill, Barrington, Cambridgeshire
Creators: name: Malim, Tim
Publisher: name: Archaeology Data Service
Year: 2002

description: Proceedings of the Cambridge Antiquarian Society, 86, 13-56
description: For many years, fieldwalking on the site has produced pottery, coins, brooches and other artefacts from all periods, but the main focus of activity appears to have been between the Bronze Age and the Anglo-Saxon period. A ring-ditch has been interpreted as a Bronze Age burial monument, pits and pottery have been attributed to the Iron Age, and palisade trenches, various metal objects and coins appear to date to Roman times. The find of a hoard of six gold staters with a possible votive significance found at a crossing point of the River Rhee 1km to south of site is noted with possible links to a communication route. Apart from the Bronze Age burial mound the site was re-used as a cemetery in Anglo-Saxon times but there is one burial which has been dated to the first century AD. The site is discussed in its regional context with an emphasis on the Iron Age. There are separate sections on: `Pottery' by Morag Woudhuysen (33--8) and an appendix on `The decorated pottery: is it Iron Age or Anglo-Saxon?' (50--3); `Faunal remains' by Simon J M Davis (41--6); `Human remains' by Corinne Duhig (46); `The environment' by Peter Murphy (46).
An Anglo-Saxon cemetery at Oakington, Cambridgeshire
Creators: name: Taylor, Alison
name: Duhig, Corinne
name: Hines, John
Publisher: name: Archaeology Data Service
Year: 2002

description: Proceedings of the Cambridge Antiquarian Society, 86, 57-90
description: Digging for the creation of nursery gardens in the 1920's exposed several graves containing four skeletons, one male with a spear and shield-boss over his head and three coloured glass beads. Villagers also noted lots of bone on the surface of the field. In 1993, excavations for the construction of a playground exposed more human bones and a sixth-century brooch. Two ditches of early prehistoric date and flints from the Mesolithic and Neolithic were noted beneath one of the graves. There were twenty-five graves in total containing twenty-six individuals, as two were in a shared grave. Other bone evidence suggests that the cemetery may have contained more than thirty-five individuals, many of which were children under the age of twelve. It is noteworthy that there is a high prevalence of cruciform and small long brooches in the female graves as in the cemetery at Girton College. This type of brooch is particularly characteristic of the costume of Anglian women. It is thought that the cemetery dates somewhere between 500--70 AD which is somewhat supported by the find of a square headed brooch produced locally around this time. All artefacts are typical of a sixth-century Anglian cemetery although the individuals from this site do share particular hereditary peculiarities. There is an appendix on `skeletal remains -- methods and glossary' (89).
SnS2 nanoplates as stable anodes for sodium ion and lithium ion batteries
Creators: name: Yihao Xie
name: Mouping Fan
name: Shen, Tong
name: Qingwen Liu
name: Chen, Yu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology

description: Tin disulphide (SnS2) nanoplates with an average lateral size of ~40 nm and thickness of approximately 7 nm were synthesised through a facile hydrothermal method between SnCl4·5H2O and thioacetamide. The as-synthesised SnS2 nanoplates exhibit improved electrochemical performances for both lithium-ion batteries (LIBs) and sodium-ion batteries (SIBs). In the LIBs electrochemical tests, anode consisting of SnS2 nanoplates presents a stable reversible capacity of 515 mAh/g under a current density of 0.1 A/g after 50 cycles. When utilising SnS2 nanoplates as SIB anode, a reversible capacity of 241.5 mAh/g is delivered at the 50th cycle under a current density of 0.1 A/g, retaining 70% of the first reversible capacity (349 mAh/g). Furthermore, to explore the practical application of SnS2 anode for sodium storage, an Na+ full cell is assembled by pairing SnS2 anode with Na3V2(PO4)3 cathode. The Na+ full cell delivers an initial discharge capacity of 346 mAh/g and slowly decays to 195 mAh/g after 50 cycles at a current density of 0.5 A/g.
title: Heimatbuch Dübendorf 1988
title: Dübendorfer Heimatbuch
titleType: AlternativeTitle
Creators: name: Becker, Max
name: Brunner, Margrit
name: Diener, Heinrich
name: Eisenring, Herbert
name: Gurtner-Kugler, René
name: Gysin, Bob
name: Hächler, Bruno
name: Höhn, Max H.
name: Korthals, Max
name: Kuhnt, Achim
name: Landolt, Kurt
name: Lebert, Fritz
name: Lutz, Heinrich
name: Maeder, Hugo
name: Rickenmann, Bernhard
name: Schläpfer, Ernst
name: Schwyzer, Martin
name: Senn, Margrit
name: Trachsler, Trudi
name: Trachsler, Hans-Felix
name: Weber, Elisabeth
name: Wyss, Pit
name: Zumstein, Ueli
Publisher: name: Verkehrs- und Verschönerungsverein
Year: 1988
Subjects: subject: 914 Geografie Europas und Reisen in Europa
subject: 949 Geschichte anderer Teile Europas
subject: Dübendorf
subject: Heimatkunde

description: Enthält eine Chronik der Gemeinde Dübendorf vom 1. Oktober 1987 bis 30. September 1988
Carbazole-driven ratiometric fluorescence turn on for dual ion recognition of Zn2+ and Hg2+ by thiophene-pyridyl conjugate in HEPES buffer medium: spectroscopy, computational, microscopy and cellular studies
Creators: name: Mahapatra, Ajit Kumar
name: Rajkishor Maji
name: Kalipada Maiti
name: Sanchita Mondal
name: Ali, Syed Samim
name: Saikat Kumar Manna
name: Prithidipa Sahoo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: Carbazole-based thiophene-pyridyl conjugate (L) was synthesised and characterised. The complexation between L with Zn2+ and Hg2+ was studied in HEPES buffer medium by fluorescence, absorption and visual colour change with the detection limit of ~3.7 and ~4.8 μM, respectively. The L detects Zn2+ by bringing ratiometric change in the fluorescence signals at 418 and 515 nm, but in the case of Hg2+, the signals are observed at 418 and 365 nm, while no new band is observed at 515 nm. The structure of L has been established by single-crystal XRD and that of complexes [ZnL] and [HgL] by density functional theory calculations. TDDFT calculations were performed in order to demonstrate the electronic properties of receptors and their zinc and mercury complexes. The isolated fluorescent complexes [ZnL] and [HgL] were found to be sensitive and selective towards phosphate-bearing ions and sulfide ions, respectively, among the other anions studied. The nanostructural features such as shape and size obtained using atomic force microscopy distinguish L from its complexes formed between L and Zn2+ from that formed with Hg2+. Moreover, the utility of the conjugate L in showing the zinc recognition in live cells has also been demonstrated using RAW cells as monitored by fluorescence imaging.
An excavation at Station Quarry, Steeple Morden, Cambridgeshire
Creators: name: Piper, Laura
name: Norton, Andrew
Publisher: name: Archaeology Data Service
Year: 2010

description: Proceedings of the Cambridge Antiquarian Society, 98, 73-76
description: Investigations revealed a hollow way dated to the Late Saxon or medieval period, and the foundations of two buildings of the same date. Post-medieval ditches and a modern posthole were also recorded.
title: The Construction of the U.S.S. Monitor
Creators: name: Thompson, Stephen C.
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1987

description: In the centuries preceding the American Civil War, the large wooden sailing ship was the mainstay of the world's navies. Then, in the spring of 1861, Stephen Mallory, Secretary of the Navy of the Confederate States of America, issued a challenge to the United States Navy: the South was going to fight the numerically superior wooden Navy of the U.S. in ironclad ships. The Union responded to the challenge with its own ironclad, the Monitor, but the South had the advantage of an earlier start.

The Merrimac was designed and built to fight wooden ships; the Monitor was created to fight the Merrimac. The UPS. Navy's urgent need for an ironclad led a naval review board to accept the proposed design of the Monitor after initially having rejected it. Manuscripts reveal how the board examined and turned down several proposals; they also describe how the Monitor's designer defended her against skeptics and how the construction of the vessel was organized and undertaken.

The thesis describes the formation of a cartel of northeastern iron and shipbuilding industries that sought to monopolize the construction of blue-water ironclads. This investigation of the origin of the Monitor departs from earlier studies by focusing on the construction companies rather than on Ericsson and his most visible partners.

The construction of the Monitor has never been thoroughly investigated. Most of the literature on the Monitor focuses either on Ericsson and his associates or on the dramatic meeting of the Monitor and the Merrimac; it generally ignores the actual building of the vessel. The few attempts to describe her construction contain numerous errors, particularly with respect to the operation of her innovative turret.
title: Liste de mots en chrau lue par une locutrice née à Vinh Thanh en 1985
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chrau
subject: crw

description: Social Sciences and humanities Research Council of Canada 435-2017-0498: Voicing and its transphonologization: the initiation and actuation of a sound change in Southeast Asia. Frame sentences containings target words with onset dentals and velars.
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
First discovery of a Palaeoproterozoic A-type granite in southern Wuyishan terrane, Cathaysia Block: evidence from geochronology, geochemistry, and Nd–Hf–O isotopes
Creators: name: Chen, Zhi-Hong
name: Zhao, Ling
name: Chen, Dan-Dan
name: Zhao, Xi-Lin
name: Xing, Guang-Fu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: In this study, a combined study of zircon U–Pb and Hf–O isotopes, as well as whole-rock major and trace elements and Nd isotopes has been conducted for Yangjia gneissic granite from the southern Wuyishan terrane, Southeast China, to constrain its petrogenesis and provide a new window for investigating the tectonic evolution of the Cathaysia basement. U–Pb dating for magmatic zircons yields a 207Pb/206Pb age of ca. 1.80 Ga, interpreted as the emplacement age of the Yangjia granite. The granites have relatively high K2O, Rb, Ga, Zr, Nb, Y, and Ce contents and show low Al2O3, CaO, and Ba concentrations. Their 10,000*Ga/Al ratios range between 2.8 and 3.2. Zircons from the granite have εHf(t) values ranging from −13.2 to −7.2, corresponding to THfDM2 model ages of 2.99 Ga to 2.72 Ga. The zircon δ18O values range between 6.7‰ and 9.1‰ with an average of 7.7‰. In addition, the whole-rock εNd(t) values of the granites range from −6.5 to −5.4 and the TNdDM2 model ages from 2.73 Ga to 2.82 Ga. All these geochemical and Nd–Hf–O isotopic signatures suggest an A-type affinity for the Yangjia granites, and they were likely generated by partial melting of Palaeoproterozoic parametamorphic rocks of the Wuyishan terrane in a post-collisional extensional setting. When our data is combined with existing geochronological data, it provides further evidence for the Palaeoproterozoic basement in the southern Wuyishan terrane, which records a rapid tectonic transition from post-collision to intraplate extension (1.80–1.77 Ga) related to the break-up of the supercontinent Columbia.
Assessment of radiological hazard parameters due to natural radioactivity in soils from granite-rich regions in Kütahya Province, Turkey
Creators: name: Sahin, Latife
name: Hafızoğlu, Nurgül
name: Çetinkaya, Hakan
name: Manisa, Kaan
name: Bozkurt, Engin
name: Biçer, Ahmet
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology

description: The analysis of natural radioactivity from 238U, 232Th and 40K in 357 soil samples collected from the province of Kütahya was carried out using a NaI(Tl) gamma-ray spectroscopy system at the Nuclear Physics Research Laboratory, Dumlupınar University, Kütahya, Turkey. The specific activities of 238U, 232Th and 40K in the soil samples were evaluated. From the activity concentrations of 238U, 232Th and 40K, the total absorbed outdoor gamma-ray dose rates and the corresponding annual effective dose rates were determined. The corresponding values of the external and internal hazard indices of all the soil samples were also calculated. The external gamma-ray dose rate at 1 m above the ground was directly measured at each collected soil sample location. The results obtained in this study were compared within the limits of values obtained in other cities of Turkey, those in other countries. Radiological maps of Kütahya Province were constructed from the results of this study.
title: Liste de mots en chrau lue par une locutrice née à Vinh Thanh en 1949
Creators: name: Brunelle, Marc
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chrau
subject: crw

description: Social Sciences and humanities Research Council of Canada 435-2017-0498: Voicing and its transphonologization: the initiation and actuation of a sound change in Southeast Asia. Frame sentences containings target words with onset dentals and velars.
description: Conforms to: doi:10.34847/cocoon.49aefa90-8c1f-3ba8-a099-0ebefc6a2aa7
Lettre de Abbé Lenteaume à Jean-François Séguier, 1766-09-13
Creators: name: Abbé Lenteaume
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Epigraphie

description: [transcription] Monsieur,

Vous recevez un peu tard les deux inscriptions dont je vous avais promis une copie, mais c'est que je comptais de pouvoir y joindre celle que vous souhaitiez de l'ermitage de Laval, et qui ne m'a pas été possible de les examiner plus tôt. J'y fus la semaine dernière, mais ces pierres, qui sont à l'entrée du cimetière, sont tellement dégradées par les charettes et les injures des saisons, qu'à peine [fol. 42 v] peut-on déchiffrer quelques lettres, de sorte que j'ai cru inutile de m'escrimer à les copier. Ces pierres étant d'ailleurs mutilées.

Si vous étiez curieux, Monsieur, de jeter un coup d'oeil sur le manuscrit de feu mon oncle, d'où j'ai tiré les deux inscriptions de Montagut, et qui est un petit cahier de 54 pages. J'aurais l'honneur de vous l'envoyer sur votre premier avis.

A l'égard de l'inscription du Pont du Gard, que j'ai cru pouvoir joindre aux autres, je l'ai trouvée telle qu'elle est, sur un petit bout de papier écrit de ma main, mais je n'ai pu me rappeler [fol. 43 r] ni d'où ni comment je l'ai eue. En 1745, j'étais encore à Remoulins, desservant cette paroisse et celle de Saint-Privat, par conséquent très à portée d'examiner le Pont du Gard où je passais et repassais souvent. Je ne me ressouviens cependant pas, si j'ai vu cette inscription, si je l'ai copiée sur l'original, ou si je l'ai confrontée.

Ma mémoire, bien différente de mes sentiments, commence à devenir ingrate. J'ai oublié le nom que vous donnâtes à la pièce d'argent dont vous voulûtes bien me gratifier ; oserai-je vous prier, Monsieur, de joindre à votre bien fait, le mot qui m'est échappé.

[fol. 44 r] Je m'estimerais très heureux, Monsieur, si vous vouliez bien me fournir les occasions de vous marquer les sentiments de reconnaissance et de respect avec lesquels j'ai l'honneur d'être,

Monsieur,

Votre très humble et très obéissants serviteur.

Lenteaume, curé de Montpezat

Chez Mademoiselle Benoite Soulèdre près les Carmes à Nîmes.

à Montpezat-les-Uzès, le 13e septembre 1766.
description: [personnes citées] Abbé Lenteaume
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 145_8, fol. 43-44
description: Source: ark:/12148/btv1b100152566