cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Sacrifice of Isaac in medieval and early modern German and Yiddish works
Creators: name: Irwin, Sylvia Lissner
Publisher: name: No Publisher Supplied
Year: 2014

description: In my dissertation I investigate the Biblical story of the Sacrifice of Isaac as portrayed by six authors, writing in the German or Yiddish vernacular. These vernacular texts include two medieval German plays, Der Sündenfall by Arnold Immessen, and the Heidelberger Passionsspiel; two plays by the Reformation author, Hans Sachs, Tragedia mit neun Person zu agirn. Die Opferung Isaac. Hat 3 actus and his Tragedia. Der Abraham, Lott sampt der opfferung Isaac, hat 21 person und & actus, and Sachs's Meistersang, Der ertz-Patriarch Abraham mit der opferung Isaac, ein figur Jesu Christi; the Reformation play Drey liebliche nützliche Historien der dreier Erzveter und Patriarchen Abrahams, Isaacs und Jacobs, aus dem Ersten buch Mosi, in Deudsche reim verfasset durch Joachimum Greff von Zwickaw, zu spielen und zu lessen tröstlich. Wittemberg 1540 by Joachim Greff; and two Yiddish texts of the Early Modern period, Shira fun Yitzkhak and Akêdass Yizhak.  In addition to a literary analysis of these works, I examine the Christian texts' use of religious and literary typology, as well as their respective inclusion of Catholic, Protestant and Jewish exegesis in their depiction of the Sacrifice ofIsaac. My analysis of the German-language texts also addresses two visual works, the Verdun Altar and the Biblia pauperum, to illustrate the depiction of this Biblical theme in visual art.These works chosen evidence the rise of new forms of popular religion, characterized by their choice of vernacular language, new means of addressing religious ideas to the public, new authority figures (authors, not clergy), and the role of print culture. My examination of these literary works demonstrates how sectarian theology informed their writing, including whether - and if so how - these texts offered religious polemics. I argue that, in addition to their didactic and entertaining nature, the Jewish and Protestant works promulgated their own religious values in part by responding to competing religious traditions. By contrast, the pre-Reformation Catholic texts examined do not exhibit such a multiplicity of intent, functioning predominantly as didactic works and offered no such polemic.
Mechanisms of P-TEFb regulation and recruitment by Tat
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Interactions between viral and host proteins are essential for replication of the human immunodeficiency virus (HIV). For example, HIV RNA recruits the host transcriptional machinery to the long terminal repeat (LTR) promoter. However, basal transcription from the HIV LTR is highly inefficient and requires the capture and recruitment of host regulators to enhance viral transcription. The key steps at which host and viral transcriptional regulation interface provide windows into host transcription and the viral requirements for efficient replication. Efficient elongation by RNA polymerase II (Pol II) is critical for the HIV transcription, and the virally encoded Tat protein is essential for this process. To stimulate elongation, Tat recruits the cellular positive transcription elongation factor b (P-TEFb) specifically to the HIV LTR. This interaction facilitates stimulation of Pol II and alleviates inhibition of negative transcription elongation factors. Interestingly, Tat not only recruits P-TEFb to the HIV LTR, but also increases the total active P-TEFb population to maximally enhance HIV transcription. Disruption of these Tat-dependent activities results in abortive HIV transcripts, which is prohibitive to viral growth and replication. Tat and its host co-factor, P-TEFb, are essential for HIV-1 survival in its host. Presently, the relatively poor structural understanding of cellular P-TEFb organization in its active and inactive forms has made it difficult to understand precisely how Tat modulates P-TEFb activity. It is unknown whether competition between Tat and host regulators for P-TEFb binding is direct or indirect. Moreover, preliminary studies suggest that additional unidentified components of these complexes may exist, and these uncharacterized factors may play a role in P-TEFb regulation and possibly Tat transactivation of the HIV LTR. I propose to take a more precise structural and biochemical approach to characterizing inactive, active, and Tat-bound P-TEFb complexes in an effort to better understand Tat function and uncover novel therapeutic targets.
DNA Damage and NK cell recognition of HIV-infected cells
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: HIV has infected more than 60 million people worldwide ands has led to more than 23 million deaths. At present, there are about 40 million people who are living with HIV infection, and there were 5 million new infections in 2004. As part of the innate immune system, natural killer (NK) cells might have an important role in host defense against HIV infection. How NK cells recognize and kill virus-infected cells is currently not well understood, but recent studies suggest that they recognize proteins that cells make as a response to viral infections. Expression of these proteins in normal cells is induced by a major “distress pathway” in cells, which is activated when the cell’s DNA is damaged. HIV is known to activate the same distress pathway, and we therefore propose to determine its role in increasing expression of these proteins in cells infected with HIV. Our aim is to understand how cells normally respond to infection in order to potentially enhance such responses and at the same time reveal how viruses sometimes evade these pathways. This knowledge will be applied towards developing therapies to reduce the development of AIDS.
Investigating the role of mce2 operon in M.tb infection
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Lay Abstract: The objective of my dissertation project is to understand how a bacterium that causes tuberculosis (TB) establishes long-term infection using a mouse model of TB. It is estimated that more than 13 billion people are infected with Mycobacterium tuberculosis, the bacterium that causes TB, and these infected individuals result in 8.8 million new cases of tuberculosis and 1.7 million deaths annually. It is the number one killer of those individuals who are simultaneously infected with HIV/AIDS. HIV and TB comprise a lethal combination, each speeding the progress of the other. An individual co-infected with both HIV and TB is many times more likely to become sick with TB than someone who is infected with TB alone. It is estimated that TB is responsible for 10% of AIDS deaths worldwide. Mycobacterium tuberculosis is a slow growing bacterium that thrives in oxygen and blood rich areas of the body, such as lungs. Tuberculosis can exist in two forms: latent and active. Latent tuberculosis means that a person has the TB causing bacterium in their body but cannot spread it to others. A person carrying the latent TB has the potential of acquiring active tuberculosis. Active TB means that the infection is spreading in a personï¿½s body and it is at this point that the disease can be spread to others. TB in the lungs is spread to others via coughing or laughing. At this time no one knows how M. tuberculosis is able to stay latent inside a human body for many years. Understanding this mechanism could lead to development of new vaccines and drugs for prevention and treatment of tuberculosis. My project will look at a collection of genes called mce2 inside M. tuberculosis that we think is responsible for latent TB. Previous studies in the lab I work with showed that another related collection of genes called mce1 was associated with latent TB. I plan to initially disrupt this collection of genes and subsequently study the effect of this disruption during both the course of macrophage infection as well as in vivo mouse infection.
Camptochaeta Hippa & Vilkamaa 1994
Creators: name: Vilkamaa, Pekka
name: Menzel, Frank
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Sciaridae
Camptochaeta

description: Camptochaeta Hippa & Vilkamaa, 1994
complexa (Rudzinski & Baumjohann, 2009) comb. n. —PAL
description: Published as part of Vilkamaa, Pekka & Menzel, Frank, 2019, Re-classification of Lycoriella Frey sensu lato (Diptera, Sciaridae), with description of Trichocoelina gen. n. and twenty new species, pp. 1-67 in Zootaxa 4665 (1) on page 50, DOI: 10.11646/zootaxa.4665.1.1, http://zenodo.org/record/4000553
Agenioideus spiniprivus
Creators: name: Gadallah, Neveen S.
name: Schmid-Egger, Christian
name: Brothers, Denis J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Agenioideus
Agenioideus spiniprivus

description: Agenioideus spiniprivus (Priesner, 1955)
Distribution in the Arabian Peninsula: Saudi Arabia (Gadallah & El-Barty 2011), United Arab Emirates (Schmid- Egger 2017).
Extralimital distribution: Egypt (Priesner 1955; Wolf 1990b).
description: Published as part of Gadallah, Neveen S., Schmid-Egger, Christian & Brothers, Denis J., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Pompilidae, pp. 153-173 in Zootaxa 4754 (1) on page 159, DOI: 10.11646/zootaxa.4754.1.16, http://zenodo.org/record/3719039
Policy purpose from formation to implementation in the New York State Brownfields Cleanup Program
Creators: name: Himmelfarb, Kathryn
Publisher: name: No Publisher Supplied
Year: 2014

description: This dissertation examines the New York State (NYS) Brownfields Cleanup Program (BCP). The BCP is a state voluntary brownfields cleanup program for private developers. Participants in the BCP do a site cleanup in compliance with a plan approved by the NYS Department of Environmental Conservation (DEC), and then receive some liability release and varying amounts of refundable tax credits against project costs, including some costs not directly related to the cleanup.    In the dissertation I use case study methods to document the stated purposes of the BCP throughout its development and compare them to the observed and expected outcomes of the program as it has been implemented, from 2003-2012. The BCP is a program that has been variously characterized by policy stakeholders, the media and in its authorizing legislation as fulfilling purposes including community development, environmental cleanup, and economic revitalization.    Whether all of these purposes can be achieved in one program is both a theoretical and an empirical question. In the dissertation I examine the underlying assumptions of the BCP as an example of policy integration, and explore the relationship of this assumption to various dimensions of the geography of program participation. I conclude that the program is not just a "cleanup" program, as its name implies, but is also not achieving the multiplicity of outcomes attributed to it. I suggest that an interdisciplinary planning orientation towards brownfields and other similarly multi-sector policy problems is an important strategy for introducing transparency and democratic models of power into the policy process.
PI3K/Akt Inhibition in Breast Cancer by 3,3'Diindolylmethane
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The goal of the proposed project is to determine the anti-cancer mechanism of 3,3’-diindolylmethane (DIM), an active metabolite of indole 3-carbinol (I3C), in breast cancer cells. Indole-3-carbinol is the focus of much research into its possible anti-carcinogenic and antioxidant effects. Consumption of indole-3-carbinol might influence cancer incidence due to its ability to alter estrogen metabolism and cell cycle regulation to reduce cell proliferation. This project focuses on the role of the PI3K/Akt cell signaling pathway, which mediates growth, survival, and chemotherapy resistance.

 Components of this PI3K/Akt signaling pathway are frequently mutated or overexpressed in breast cancer. In fact, a recent review states that the gene encoding the catalytic subunit of PI3K is the most common mutation in breast cancer (Oncogene 2007;26:1338-45). In addition, Her-2, a growth factor receptor that activates the PI3K/Akt pathway, is amplified in 10-30% of breast cancers. Activation of the PI3K/Akt pathway also plays a role in resistance to current breast cancer therapies like trastuzimab (Herceptin) and tamoxifen. Compounds, like DIM, that inhibit this central pathway could be effective against breast cancers with certain genetic aberrations and could help to overcome resistance to current therapies.

 DIM’s effects on proliferation and cell cycle will be studied by direct cell counting, DNA staining and analysis by flow cytometry, cyclin D and myc expression, and NF-?B activation. Protein expression will be determined by Western blotting and protein activation (phosphorylation) will be determined by Western blotting using phospho-specific antibodies, or by immunoprecipitation of individual proteins followed by Western blotting for phosphotyrosine. Involvement of specific components of the PI3K/Akt pathway in DIM’s cytostatic effects will be determined by overexpression of the specific proteins to potentially reverse DIM’s effects. Finally, PI3K activation and activity will be determined by immunofluorescence and kinase assays, respectively.

 By studying the mechanism whereby DIM inhibits this central breast cancer cell signaling pathway, we hope to identify a specific target for future investigation. Since breast cancer is a heterogeneous disease with specific genetic profile in each patient, our ultimate goal would be to identify specific mutations or overexpressed proteins that would predict those that can respond the best to DIM treatment.
Preparation of Sulfonated Poly(ether ether ketone) Membranes and Salinity Gradient Energy Conversion
Creators: name: Guo, Yumeng
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 401703
subject: Energy generation, conversion and storage (excl. chemical and electrical)

description: Salinity gradient power harvesting utilizes the chemical potential energy difference between seawater and freshwater or solutions with varying salt concentrations. This energy can be efficiently converted into electricity via reverse electrodialysis on ion-selective membranes. However, current ion-selective membranes face challenges such as low mechanical strength, poor ion selectivity, and ion permeability. The development of high-performance ion-selective membranes is crucial for advancing the industrial application of salinity gradient energy conversion technology and expanding its scope. Sulfonated poly(ether ether ketone) (SPEEK) has garnered attention because of its rich surface charge and excellent mechanical properties. However, its relatively low output power density limits its potential. This thesis optimizes the interaction between SPEEK and other polymers and porous nanomaterials to construct composite membranes with high mechanical properties, high stability, improved ion selectivity, and permeability, enabling more efficient energy conversion.
On scattering anisotropy for accurate modeling of radiation transfer
Creators: name: Hunter, Brian D.
Publisher: name: No Publisher Supplied
Year: 2014

description: It is well known that the discrete-ordinates method (DOM) suffers from two shortcomings:  1) numerical smearing (or false scattering) error due to spatial discretization, and 2) ray effect error due to limited number of discrete angular directions. It is less aware that all numerical methods based on the discretization solution of the integral-differential equation of radiation transfer (ERT), such as the finite volume method (FVM), experience similar issues. In this dissertation, the existence of a third type of numerical error, termed “angular false scattering” for anisotropic scattering media, is revealed and presented for both DOM and FVM.  In all practical applications, radiation scattering is anisotropic in nature.  Angular discretization of anisotropy may not preserve the scattering phase-function asymmetry factor, resulting in an artificial alteration of medium scattering properties - angular false scattering.   Phase-function normalization was the prevailing approach in DOM to numerically conserve scattered energy.  In this dissertation, this technique is employed, for the first time, to simultaneously conserve both scattered energy and asymmetry factor for both DOM and FVM. Traditionally, the solid-angle splitting approach was implemented to conserve scattered energy for FVM. It is found, however, that extremely high splitting levels are required to preserve asymmetry factor for strongly scattering media, substantially increasing computational cost. Here, two novel phase-function normalization techniques are developed for FVM and DOM radiation transfer analysis to specifically mitigate angular false scattering errors by simultaneously conserving scattered energy and asymmetry factor.  Normalization approaches are formulated for both diffuse and ballistic radiation transfer.  Radiation transfer predictions generated using both the DOM and FVM with the normalization approaches are compared with statistical Monte Carlo predictions to gauge their accuracy and efficiency.  Proper phase-function normalization is shown to greatly improve radiation transfer accuracy, while concurrently improving computational efficiency by allowing for substantial reduction in both discrete direction number and solid-angle splitting density.  Application of phase-function normalization for ballistic radiation transfer is found to be crucial.  Additionally, phase-function normalization allows for accurate conformity between DOM and FVM solutions of the ERT.
Agenioideus seminiger
Creators: name: Gadallah, Neveen S.
name: Schmid-Egger, Christian
name: Brothers, Denis J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Agenioideus
Agenioideus seminiger

description: Agenioideus seminiger (Taschenberg, 1880)
Distribution in the Arabian Peninsula: Saudi Arabia (Gadallah & El-Barty 2011).
Extralimital distribution: Cyprus, Israel, Malta, Mauritania, North Africa, Sudan (Priesner 1955; Haupt 1962; Wahis 1997).
description: Published as part of Gadallah, Neveen S., Schmid-Egger, Christian & Brothers, Denis J., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Pompilidae, pp. 153-173 in Zootaxa 4754 (1) on page 159, DOI: 10.11646/zootaxa.4754.1.16, http://zenodo.org/record/3719039
Agenioideus vesanus
Creators: name: Gadallah, Neveen S.
name: Schmid-Egger, Christian
name: Brothers, Denis J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Agenioideus
Agenioideus vesanus

description: Agenioideus vesanus (Kohl, 1906)
Distribution in the Arabian Peninsula: Yemen (Kohl 1906 as Pompilus vesanus; Wolf 1990b, 1997).
Extralimital distribution: Jordan, Syria, Turkey (Wolf 1997; Yildirim & Wahis 2011).
description: Published as part of Gadallah, Neveen S., Schmid-Egger, Christian & Brothers, Denis J., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Pompilidae, pp. 153-173 in Zootaxa 4754 (1) on page 159, DOI: 10.11646/zootaxa.4754.1.16, http://zenodo.org/record/3719039
Hemineurina Frey sensu Tuomikoski 1960
Creators: name: Vilkamaa, Pekka
name: Menzel, Frank
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Sciaridae
Hemineurina

description: Hemineurina Frey, 1942 stat. n. (former L. inflata group)
abbrevinervis (Holmgren, 1869) comb. n. —PAL acerstyla (Mohrig & Krivosheina, 1987) comb. n. in Mohrig et al. (1987) —PAL algida (Frey, 1948) restit. et comb. n. —PAL conspicua (Winnertz, 1867) comb. n. —NEA / PAL
= polychaeta (Pettey, 1918) in Pettey (1918a) —NEA flavicornis (Mohrig & Mamaev, 1985) comb. n. in Mohrig et al. (1985a) —PAL flavipeda (Mohrig & Krivosheina, 1987) comb. n. in Mohrig et al. (1987) —PAL gerbatshevskayae (Antonova, 1975) comb. n. —PAL gigastyla (Mohrig & Menzel, 1992) comb. n. —PAL heydeni (Winnertz, 1867) comb. n. —PAL honesta (Menzel, 1992) comb. n. in Menzel (1992b) —PAL inflata (Winnertz, 1867) comb. n. —NEA / PAL
= difficilis (Grzegorzek, 1884) —PAL
= interdicta (Grzegorzek, 1884) —PAL
= nitens (Winnertz, 1867) —PAL
= subvenosa (Mohrig & Krivosheina, 1983) in Mohrig et al. (1983a) —PAL johannseni (Enderlein, 1912) comb. n. —NEA
= mesochra (Shaw, 1941) —NEA
= nigricans (Johannsen, 1912) [preocc.]—NEA laevigata (Lengersdorf, 1926) comb. n. —PAL modesta (Staeger, 1840) comb. n. —NEA / PAL
= arctica (Holmgren, 1869) —PAL
= conglomerata (Pettey, 1918) in Pettey (1918a) —NEA
= ecalcarata (Holmgren, 1869) —PAL
= frigida (Holmgren, 1869) [preocc.]—PAL
= fumatella (Lundbeck, 1898) —NEA
= globiceps (Becher, 1886) syn. n. —PAL
= groenlandica (Holmgren, 1872) —NEA
= holmgreni (Rübsaamen, 1894) —NEA / PAL neimongolana (Zhang & Yang, 1990) comb. n. —PAL nudata (Mohrig & Mamaev, 1990) comb. n. in Mohrig et al. (1990) —PAL postconspicua (Mohrig, 1985) comb. n. —PAL proconspicua (Mohrig, 1985) comb. n. —PAL riparia (Holmgren, 1883) comb. n. —PAL speciosissima (Strobl, 1898) comb. n. —PAL thuringiensis (Menzel & Mohrig, 1991) comb. n. —PAL unguicauda (Malloch, 1923) restit. et comb. n. —NEA venosa (Staeger, 1840) comb. n. —PAL
= crassivenosa (Lengersdorf, 1943) —PAL
= lepida (Winnertz, 1867) —PAL
= praevenosa (Mohrig & Menzel, 1990) in Menzel et al. (1990) —PAL ventrosa (Lengersdorf, 1941) comb. n. —PAL
description: Published as part of Vilkamaa, Pekka & Menzel, Frank, 2019, Re-classification of Lycoriella Frey sensu lato (Diptera, Sciaridae), with description of Trichocoelina gen. n. and twenty new species, pp. 1-67 in Zootaxa 4665 (1) on pages 50-51, DOI: 10.11646/zootaxa.4665.1.1, http://zenodo.org/record/4000553
Artemisinin disrupts estrogen receptor-alpha and cell growth
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: A critical challenge in the treatment of breast cancer is the need to develop therapeutic agents that selectively inhibit growth of breast cancer cells with reduced side effects. There has been only a limited amount of research directed at the identification and characterization of natural ingredients in plants that can be used in breast cancer prevention and treatment. Natural plant compounds provide potential sources of new classes of chemotherapeutic agents to control breast cancer with reduced side effects. One such promising phytochemical is Artemisinin, a sesquiterpene lactone that was isolated from a Chinese plant Artemisia annua (commonly known as qinghaosu or sweet wormwood) and has been used as a Chinese herbal medicine for the last 2000 years to treat fever. Since the 1970s Artemisinin has been extensively as an anti-malaria drug that is effective against multi-drug resistant strains of malarial parasites. We have discovered a previously unknown property of Artemisinin in that treatment of human breast cancer cells with this plant compound disrupts estrogen responsiveness and stops cell growth, and we propose to understand the molecular mechanism of this process.

 Artemisinin acts in breast cancer cells by inhibiting the production of the estrogen receptor-alpha (ERα) gene without altering the level of the related estrogen receptor-beta gene (ERα). Our hypothesis is that Artemisinin–regulated cellular pathways selectively inhibit the production of ERα and arrest the growth of estrogen responsive breast cancer cells by altering the function of nuclear cellular proteins (transcription factors) that are used by breast cancer cells to enhance the synthesis of the ERα gene.

 We plan to use molecular and cellular approaches to identify the Artemisinin–regulated proteins from human breast cancer cells that alter the production of ERα, and thereby disrupt estrogen responsiveness and growth of human breast cancer cells. We will identify the region of the ERα gene promoter that is bound by Artemisinin responsive breast cancer cell nuclear proteins (called transcription factors) to control production of that gene. We also will assay Artemisinin–regulated changes in the ability of these transcription factors to bind to the ERα gene DNA in intact breast cancer cells. Breast cancercells will be generated in which the cellular production of the Artemisinin–regulated components will either disrupted or enhanced, and assess the subsequent effects on the Artemisinin–regulated ERα production and growth arrest.

 Given the limited information about the role of Artemisinin–type compounds in the treatment of breast cancer, our study will provide the necessary first experimental information needed for a detailed understanding of how Artemisinin can disrupt estrogen responsiveness and growth of breast cancer cells.
Lycoriella Frey 1942
Creators: name: Vilkamaa, Pekka
name: Menzel, Frank
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Sciaridae
Lycoriella

description: Lycoriella Frey, 1942
= Niadina Rapp, 1946 abbreviata (Walker, 1848) —NEA aberrans Tuomikoski, 1960 —PAL acutostylia Mohrig & Menzel, 1990 in Menzel et al. (1990) —PAL agraria (Felt, 1897) —AUS / NEA / PAL
= cellaris (Lengersdorf, 1934) —PAL
= multiseta (Felt, 1897) —AUS / NEA
= rufula Tuomikoski, 1959 in Tuomikoski (1959b) —PAL
= stramentorum (Frey, 1948) —PAL aliena (Winnertz, 1867) —PAL altaica Komarov, 2009 —PAL antrocola Yang & Zhang, 1995 —ORI approximatonervis (Frey, 1948) —PAL attenuata (Rübsaamen, 1898) —NEA
= latipennis (Lundbeck, 1898) —NEA auripila (Winnertz, 1867) —PAL
= detrita (Frey, 1953)—PAL
= tenuis (Winnertz, 1867) —PAL
= urbana (Winnertz, 1867) —PAL bispinalis Yang & Zhang, 1987 in Yang & Zhang (1987a) —PAL brevipila Tuomikoski, 1960 —PAL deserticola (Mohrig & Mamaev, 1983) —PAL epleuroti Yang & Zhang, 1987 in Yang & Zhang (1987a) —PAL
description: Published as part of Vilkamaa, Pekka & Menzel, Frank, 2019, Re-classification of Lycoriella Frey sensu lato (Diptera, Sciaridae), with description of Trichocoelina gen. n. and twenty new species, pp. 1-67 in Zootaxa 4665 (1) on page 51, DOI: 10.11646/zootaxa.4665.1.1, http://zenodo.org/record/4000553
Agenioideus smithi
Creators: name: Gadallah, Neveen S.
name: Schmid-Egger, Christian
name: Brothers, Denis J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Agenioideus
Agenioideus smithi

description: Agenioideus smithi (Ritsema, 1880)
Distribution in the Arabian Peninsula: United Arab Emirates (Schmid-Egger 2017), Yemen (Wolf 1990b; Schmid- Egger 2017).
Extralimital distribution: India, Sri Lanka (Wolf 1990b).
description: Published as part of Gadallah, Neveen S., Schmid-Egger, Christian & Brothers, Denis J., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Pompilidae, pp. 153-173 in Zootaxa 4754 (1) on page 159, DOI: 10.11646/zootaxa.4754.1.16, http://zenodo.org/record/3719039
A new perspective on team leadership
Creators: name: Kim, Mee Sook
Publisher: name: No Publisher Supplied
Year: 2014

description: The present study adopts a relational approach to leadership and examines a leader’s role in enhancing team members’ attitudes. Previous studies on the leader’s social capital found that a leader’s central position in social networks increased the leader’s prestige and influence in the organization. Extending this research, the current study proposes that the leader’s central position in social networks, especially with peer leaders and superiors, should enable the leader to provide valuable resources for the team, and as a result, lead team members to feel more supported and valued by the organization. In addition to the leader’s centralities in the networks, the present study further suggests that team members judge their leader’s power based on their own information, separate from the actual power that the leader holds. The leader’s power perceived by team members is also proposed to positively affect team members’ perceptions of organizational support provided for their team. Applying the theory of perceived organizational support to the team-level, this dissertation uses the notion of team climate for organizational support to capture the degree to which team members feel supported by the organization as a team. Furthermore, it is proposed that not all leaders are dedicated to their teams and motivated to utilize their social capital for the sake of their teams. Therefore, the present study proposes that the leader’s team commitment will moderate the relationship between the leader’s centrality and team climate for organizational support and the relationship between the leader’s perceived power and team climate for organizational support, respectively. Team climate for organizational support enhanced by the leader’s centrality and perceived power is further hypothesized to positively affect team-level attitudes including team efficacy and cohesion.   Data was collected from companies located in South Korea using paper surveys. The final sample consists of 44 executives, 84 leaders, and 469 team members. The study used hierarchical regression to test hypotheses. The results show that the leader’s centralities in both advice and friendship networks with peer leaders were positively related to team climate for organizational support. However, the leader’s centralities in advice and friendship networks with superiors had either marginal or no impact on team climate for organizational support. The leader’s power perceived by team members was also positively and strongly related to team climate for organizational support. Contrary to expectations, however, the leader’s team commitment did not moderate the hypothesized relationships. Team climate for organizational support was positively related to team efficacy and team cohesion as expected. Additional findings, implications for theory and practice, limitations, and directions for future research are discussed.
HIV-1 Tat and P-TEFb complex: an old story with a fresh look
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Acquired Immune Deficiency Syndrome (AIDS) is one of the most serious and deadly diseases in human history and HIV (Human Immunodeficiency Virus) is the causative reagent of this disease. Although numerous drugs have emerged, there is no cure for AIDS to date. This virus encodes 19 proteins that are important for viral maturation,replication and infection. One of these proteins, Tat, plays an essential role in transcription of viral genes. What this protein does is to hijack the host transcription apparatus in order to stimulate its own gene expression. It has been well characterized that the host transcription elongation factor P-TEFb is the target of the viral protein Tat, but other than that, little is known about the details. Recently, we have further investigated the connection between Tat and P-TEFb, resulting in the identification of two novel host proteins that are also important for Tat-mediated transcription. This project is dedicated to fully dissecting the functions of these two proteins and hence further understanding of the HIV gene expression. This might potentially identify novel therapeutic targets for the treatment of HIV-1 infection.
Provider Communication and Health in Breast Cancer Survivors
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The health concerns of cancer survivors and shortcomings in communication between cancer patients and their providers have created an imperative for studying the effect of physician-patient communication on breast cancer survivors’ long-term health. The proposed study explores how breast cancer survivors’ perceptions of their communication with healthcare providers affect their health behaviors and outcomes over the long-term. There is a need to examine whether breast cancer survivors’ perceived control over their health, health behaviors, and health outcomes over ten years are predicted by the quality of communication these women experience with their healthcare providers.

 The aims of this project are to:

 - Identify the specific components of physician-patient communication (e.g., information, emotional support) and how they relate to one another. This includes ascertaining whether different components of communication underlie a single construct or multiple, related constructs. We will also develop indices of communication based on preliminary analyses for use in multivariate models.

 - Conduct cross-sectional and longitudinal analyses using data from the treatment period and 5-years survival and data from 5 and 10 years survival to discern the long-term impact of provider-patient communication on women’s perceived control over their health, health behaviors, and subsequent health outcomes.

 - Examine relationships among breast cancer survivors’ perceptions of doctor-patient communication and individual characteristics, such as race/ethnicity, age, perceived social support, and self-esteem.

 - Analyze data at ten years from survivors and a comparison cohort of women who have never had breast cancer (survivors’ female friends who were referred to the study) to identify differences between breast cancer survivors’ need for effective provider communication and other women’s needs.

 This approach serves to improve the quality of survivorship care through reframing cancer as a chronic condition, informing patient and provider-based communication interventions, and bringing breast cancer survivorship care to the forefront of chronic care research.
A knowledge-sharing communication network approach to transactive memory systems in virtual work arrangements
Creators: name: Kim, Young Hoon
Publisher: name: No Publisher Supplied
Year: 2014

description: This study explores the relationships between expertise recognition—which is the key element of transactive memory systems (TMS)—and virtuality, while taking into account the effects of network diversity and network closure. It also examines the relationships between expertise recognition and knowledge-seeking behaviors and between expertise recognition and information-allocation. This study sheds light on the difficulties that individuals may face in establishing TMS in virtual work arrangements. Using hierarchical multiple regression and exponential random graph modeling, this study shows that the two main network properties, network diversity and network closure, not only influence expertise recognition positively but also moderate the effects of the structural aspects of virtuality on expertise recognition. Further, this study identifies alternating bivariate network relationships among the three main elements of TMS—expertise recognition, knowledge seeking, and information allocation—indicating that individuals’ perceptions of others’ expertise shape patterns of knowledge-sharing.
Novel approaches to produce active, folded HIV-1 Tat
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: HIV replication in a host cell requires efficient copying of the viral RNA. This process requires an HIV protein called Tat, but the role of this protein is not very well understood because it has not been possible to produce samples of Tat using standard methods. Tat is especially prone to damage during production and purification, and no strategies currently exist to introduce chemical modifications that are essential for full Tat function. As a result, the samples of Tat that have been made to date are heterogeneous mixtures, partially damaged and missing chemical groups that are normally present in Tat in infected cells. To overcome these problems, we propose to create brand new methods to make Tat. In particular, in order to avoid damage and introduce the proper modifications, we have made Tat in a test tube rather than a cell. Tat is generally considered too big to make by chemical synthesis, but we utilized optimized methods we developed previously to make peptides nearly twice as big. To force Tat to adopt the correct three-dimensional shape, we will invent gentle procedures to allow it to sample many different arrangements and to trap the correct structures by binding them to human partner proteins. The human partner called cyclin T1, for example, will be used as a mold to encourage Tat to adopt the correct shape. These approaches have not been tried before. Our strategies are made possible by unique advances in peptide synthesis methods, recent discoveries about chemical modifications of Tat and new knowledge about the partners of Tat in human cells. This work embodies new ways of thinking about the problems that have limited progress on Tat biochemistry for the last 25 years. The success of this project will enable many studies of Tat that have languished because they are currently considered intractable. By opening up new studies of Tat structure and function, this IDEA award has the potential to deliver new insights about how Tat does its job and how to block these functions with new therapeutics.
Agenioideus Ashmead 1902
Creators: name: Gadallah, Neveen S.
name: Schmid-Egger, Christian
name: Brothers, Denis J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Agenioideus

description: Agenioideus sp.
Distribution in the Arabian Peninsula: Kuwait (Al-Houty 1989 as Ageniodeus sp. 1 & sp. 2); Oman (Monks et al. 2019).
Remarks: This entry involves different species, some or all of which may be the same as named species appearing above.
description: Published as part of Gadallah, Neveen S., Schmid-Egger, Christian & Brothers, Denis J., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Pompilidae, pp. 153-173 in Zootaxa 4754 (1) on page 159, DOI: 10.11646/zootaxa.4754.1.16, http://zenodo.org/record/3719039
GPU techniques applied to Euler flow simulations and comparison to CPU performance
Creators: name: Koop, Blake
Publisher: name: No Publisher Supplied
Year: 2014

description: With the decrease in cost of computing, and the increasingly friendly programming environments, the demand for computer generated models of real world problems has surged. Each generation of computer hardware becomes marginally faster than its predecessor, allowing for decreases in required computation time. However, the progression is slowing and will soon reach a barrier as lithography reaches its natural limits. General Purpose Graphics Processing Unit (GPGPU) programming, rather than traditional programming written for Central Processing Unit (CPU) architectures may be a viable way for computational scientists to continue to realize wall clock time reductions at a Moore's Law pace. If a code can be modified to take advantage of the Single-Input-Multiple-Data (SIMD) architecture of Graphics Processing Units (GPUs), it may be possible to gain the functionality of hundreds or thousands of cores available on a GPU card. This paper details the investigation of a specific compressible flow simulation and its functionality in both CPU and GPU programming schemes. The flow is governed by the unsteady Euler flow equations and it is checked for validity against the known solution in all three directions. It is then run over varying grid sizes using both the CPU and GPU programming schemes to evaluate wall clock time reductions.
Amblyellus vegrandis
Creators: name: Gadallah, Neveen S.
name: Schmid-Egger, Christian
name: Brothers, Denis J.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Pompilidae
Amblyellus
Amblyellus vegrandis

description: Amblyellus vegrandis (Kohl, 1906)
Distribution in the Arabian Peninsula: Saudi Arabia (Gadallah & El-Barty 2011), United Arab Emirates (Schmid- Egger 2017), Yemen (Kohl 1906 as Pompilus vegrandis).
Extralimital distribution: No records.
description: Published as part of Gadallah, Neveen S., Schmid-Egger, Christian & Brothers, Denis J., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Pompilidae, pp. 153-173 in Zootaxa 4754 (1) on page 159, DOI: 10.11646/zootaxa.4754.1.16, http://zenodo.org/record/3719039
Development of an ultra-wide band-based real-time vibrator tip locating system for intelligent concrete consolidation
Creators: name: Krishnamoorthy, Raghav
Publisher: name: No Publisher Supplied
Year: 2014

description: Proper consolidation of concrete is critical to the long-term strength of concrete bridge structures. Vibration is a commonly used method to make concrete flow able and to remove the excessive entrapped air, therefore contributing to proper concrete consolidation. To introduce vibrations to freshly placed concrete, various tools such as internal vibrators are widely used in the construction industry. Producing a dense concrete without segregation with these tools requires an experienced vibrator operator. Inexperienced vibrator operators tend to over-consolidate or under-consolidate concrete. Many of these quality problems have their roots in the lack of quality control methods that can provide real-time feedback on the quality of concrete consolidation to vibrator operators. The proposed research involves the development of a real-time wireless sensing-based internal vibrator tracking system to support intelligent concrete consolidation operations. Specifically, the research team will explore the use of an Ultra Wideband (UWB) tracking system to realize precise localization of internal vibrators. Multiple tags will be attached to each vibrator for deriving its precise poses. Computer programs will be developed to track tags, to infer vibrator poses, and to visualize operators' vibration effort in real-time. Once a vibrator is tracked, the vibration location, time, and depth associated with this vibrator will be displayed on a computer in real-time. A vibrator operator can leverage such information to visualize the distribution of his vibration effort, and spot areas that may need mitigation actions. The new concrete consolidation tool will allow contractors to proactively address concrete consolidation issues, a problem common to many concrete construction projects.
Lycoriella felix
Creators: name: Vilkamaa, Pekka
name: Menzel, Frank
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Sciaridae
Lycoriella
Lycoriella felix

description: felix (Schmitz, 1919) —PAL
haipleuroti Yang & Tan, 1994 in Yang, Zhang & Tan (1994) —ORI
inconspicua Tuomikoski, 1960 —PAL
ingenua (Dufour, 1839) —AET / ANT / AUS / NEA / NEO / PAL
= caesar (Johannsen, 1929) —ANT / NEA
= bigoti (Laboulbène, 1863) —PAL
= celer (Winnertz, 1867)—PAL
= debilis (Winnertz, 1867)—PAL
= decliva (Winnertz, 1867) —PAL
= flammulinae (Sasakawa, 1983) —PAL
= flaviventris (Winnertz, 1867)—PAL
= humilis (Winnertz, 1867)—PAL
= jauva (Rapp, 1946) —NEA
= mali (Fitch, 1856)—AUS / NEA / ORI / PAL
= mycorum (Frey, 1948) —AET / PAL
= pauciseta (Felt, 1897) —NEA
= pleuroti Yang & Zhang, 1987 in Yang & Zhang (1987a) —ORI / PAL
= ramicola (Kieffer, 1919) —PAL
= segnis (Winnertz, 1871) —PAL
= solani (Winnertz, 1871) —ANT / ORI / PAL
= velox (Winnertz, 1867) —PAL
= venusta (Winnertz, 1867) —PAL
= womersleyi (Séguy, 1940) —ANT
jingpleuroti Yang & Zhang, 1987 in Yang & Zhang (1987a) —ORI / PAL
jipleuroti Yang & Zhang, 1987 in Yang & Zhang (1987a) —PAL
latilobata Menzel & Mohrig, 2000 —PAL
latistyla Freeman, 1987 —PAL
lundstromi (Frey, 1948) —PAL
micria Mohrig & Menzel, 1990 in Menzel, Mohrig & Groth (1990) —PAL
minutula Mohrig & Krivosheina, 1987 in Mohrig et al. (1987) —PAL
parva (Holmgren, 1869) —NEA / PAL
= curvispina Tuomikoski, 1960 —PAL
= difficilis var. obscuratipes (Frey, 1948) —PAL
piristylata Vilkamaa, Hippa & Heller, 2013 —PAL
quadriseta Yang & Zhang, 1987 in Yang & Zhang (1987b) —PAL
sativae (Johannsen, 1912) —AET / ANT / AUS / NEA / PAL
= agarici Loudon, 1978 —AUS
= auberti (Séguy, 1940) —ANT
= brevipetiolata (Shaw, 1941) —NEA
= castanescens (Lengersdorf, 1940) —AET / AUS / ORI / NEA / PAL
= difficilis (Frey, 1948) [preocc.]—PAL
= fucorum (Frey, 1948) —PAL
= jeanneli (Séguy, 1940) —ANT
= kaiseri (Shaw, 1941) —NEA
= paucisetulosa (Frey, 1948) —PAL
= rufotincta Tuomikoski, 1959 in Tuomikoski (1959b) —PAL
= similans (Johannsen, 1925) —AUS / NEA
= solispina (Hardy, 1956) —AUS
= trifolii (Pettey, 1918) in Pettey (1918b) —NEA
similis (Winnertz, 1867) —PAL
stylata Mohrig & Mamaev, 1985 in Mohrig et al. (1985a) —NEA / PAL
suboptica Mohrig & Mamaev, 1990 in Mohrig et al. (1990) —PAL
description: Published as part of Vilkamaa, Pekka & Menzel, Frank, 2019, Re-classification of Lycoriella Frey sensu lato (Diptera, Sciaridae), with description of Trichocoelina gen. n. and twenty new species, pp. 1-67 in Zootaxa 4665 (1) on page 52, DOI: 10.11646/zootaxa.4665.1.1, http://zenodo.org/record/4000553
How X4 Emerges in HIV: Implications for CCR5 Blockers
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: One of the great mysteries of HIV is how, in about 50% of Western patients (i.e., those with Subtype B), a more deadly HIV strain emerges late in infection. The new strain, known as X4, differs from its predecessor R5, because X4 only infects CD4+ T cells (“helper” immune cells necessary for orchestrating one’s overall immune response) displaying the receptor CXCR4, whereas R5 only infects CD4s displaying CCR5. Because CXCR4 and CCR5 are found on different CD4s, X4 depletes an additional set of critical immune cells, accelerating immunodeficiency and death. Recently, the FDA began approving drugs that selectively block R5, and some researchers have touted anti-R5 therapy alone as a potentially safer alternative to current anti-HIV drugs. An open question is whether anti-R5 treatments push HIV toward the more deadly X4 variant earlier. Using a minimal mathematical model for multi-strain HIV infection that we derive from the ground up, we show that anti-R5 treatment alone likely accelerates X4 emergence and thus immunodeficiency (Weinberger et al., 2009 PLoS Comput Biol, 5(8):e1000467). But, despite X4’s late-stage ubiquity among Western/Subtype B patients, X4 has not been commonly observed in other viral subtypes such as subtype C, which represents the majority of the world’s HIV infections. We are building a model to test our theory of how X4 Virus persists in Western populations. We plan to apply specific knowledge garnered from this modeling study directly to an experimental perturbation study aimed at eradicating the scourge of X4 Virus from Western populations.