cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Impact of health and recreation on work-life balance - A case study of expatriates.pdf
Creators: name: Pranav Naithani
Publisher: name: figshare
Year: 2016
Subjects: subject: Education
subject: 130199 Education systems not elsewhere classified
subject: FOS: Educational sciences
subject: 130103 Higher Education

description: Factors influencing work-life balance are evolving at a very fast pace, thus creating a fecund ground for innovative work-life balance tools and techniques. The increasing significance of expatriates in the global workforce necessitates a targeted set of work-life balance initiatives to help expatriate workers contribute more effectively in the competitive work environment. Health and recreation are the two important life spheres which play a very important role in success or failure of an expatriate assignment. While work-life balance researches are being conducted globally in plenty, yet research on expatriate adjustment and expatriate work-life balance is still in its nascent stage especially in an expatriate dominated work environment in the Gulf Cooperation Council (GCC) countries. This research paper investigates the health and recreation spheres of expatriate academicians working in private higher education institutes in Bahrain, Oman and the UAE. The research paper illustrates and evaluates the health and recreation spheres in relation to the demographic factors of the respondents and suggests ways to improve work-life balance of expatriate employees.
Glutamic acid decarboxylase 67 haplodeficiency in mice : consequences of postweaning social isolation on behavior and changes in brain neurochemical systems
Creators: name: Nullmeier, Sven
name: Elmers, Christoph
name: D'Hanis, Wolfgang
name: Sandhu, Kiran Veer Kaur
name: Stork, Oliver
name: Yanagawa, Yuchio
name: Panther, Patricia
name: Schwegler, Herbert
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: GAD67
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Schizophrenia
subject: Dopamine
subject: Social interaction
subject: Social isolation
subject: Schizophrenie
subject: Hippocampus
subject: Interaktion
subject: Dopamin

description: Reductions of glutamate acid decarboxylase (GAD67) and subsequent GABA levels have been consistently observed in neuropsychiatric disorders like schizophrenia and depression, but it has remained unclear how GABAergic dysfunction contributes to different symptoms of the diseases. To address this issue, we investigated male mice haplodeficient for GAD67 (GAD67+/GFP mice), which showed a reduced social interaction, social dominance and increased immobility in the forced swim test. No differences were found in rotarod performance and sensorimotor gating. We also addressed potential effects of social deprivation, which is known, during early life, to affect GABAergic function and induces behavioral abnormalities similar to the symptoms found in psychiatric disorders. Indeed, social isolation of GAD67+/GFP mice provoked increased rearing activity in the social interaction test and hyperlocomotion on elevated plus maze. Since GABA closely interacts with the dopaminergic, serotonergic and cholinergic neurotransmitter systems, we investigated GAD67+/GFP and GAD67+/+ mice for morphological markers of the latter systems and found increased tyrosine hydroxylase (TH)-IR fiber densities in CA1 of dorsal hippocampus. By contrast, no differences in numbers and densities of TH-positive neurons of the midbrain dopamine regions, serotonin (5-HT) neurons of the raphe nuclei, or choline acetyltransferase (ChAT)-expressing neurons of basal forebrain and their respective terminal fields were observed. Our results indicate that GAD67 haplodeficiency impairs sociability and increases vulnerability to social stress, provokes depressive-like behavior and alters the catecholaminergic innervation in brain areas associated with schizophrenia. GAD67+/GFP mice may provide a useful model for studying the impact of GABAergic dysfunction as related to neuropsychiatric disorders.
Fieldwork on the Roman fort site at Blennerhasset, Cumbria.
Creators: name: Evans, Jeremy
name: Scull, Christopher
Publisher: name: Archaeology Data Service
Year: 2008

description: Transactions of the Cumberland & Westmorland Antiquarian & Archaeological Society, 90, 127-138
description: Reports surface collection and resistivity survey on a cropmark site. The samian and coarse wares indicate a late Neronian/early Flavian date. The fort, at 3.4ha, is the largest in Cumbria and confirms that the Roman army did not bypass the Lake District at this period, but was concerned to control the Cumbrian plain and contain the natives of the massif to the south.
Complex relationship between amino acids, fitness and food intake in Bombus terrestris
Creators: name: Archer, C. Ruth
name: Fähnle, Johannes
name: Pretzner, Maximilian
name: Üstüner, Cansu
name: Weber, Nina
name: Sutter, Andreas
name: Doublet, Vincent
name: Wilfert, Lena
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Bombus
subject: Geometric framework of nutrition
subject: Intake array
subject: Trade-off
subject: DDC 570 / Life sciences
subject: Bumblebees
subject: Hummel

description: The ratio of amino acids to carbohydrates (AA:C) that bumble bees consume has been reported to affect their survival. However, it is unknown how dietary AA:C ratio affects other bumble bee fitness traits (e.g., fecundity, condition) and possible trade-offs between them. Moreover, while individual AAs affect phenotype in many species, the effects of AA blend on bumble bee fitness and food intake are unclear. We test how the AA:C ratio that bumble bees (Bombus terrestris) consume affects their condition (abdomen lipid and dry mass), survival following food removal, and ovarian activation. We then compare ovarian activation and food intake in bees fed identical AA:C ratios, but where the blend of AAs in diets differ, i.e., diets contained the same 10 AAs in an equimolar ratio or in the same ratio as in bee collected pollen. We found that AA:C ratio did not significantly affect survival following food removal or ovarian activation; however, high AA intake increased body mass, which is positively correlated with multiple fitness traits in bumble bees. AA blend (i.e., equimolar versus pollen) did not significantly affect overall ovarian activation or consumption of each experimental diet. However, there was an interaction between AA mix and dietary AA:C ratio affecting survival during the feeding experiment, and signs that there may have been weak, interactive effects of AA mix and AA:C ratio on food consumption. These results suggest that the effect of total AA intake on bumble bee phenotype may depend on the blend of individual AAs in experimental diets. We suggest that research exploring how AA blend affects bumble bee performance and dietary intake is warranted, and highlight that comparing research on bee nutrition is complicated by even subtle variation in experimental diet composition.
ORCA 6: 	ORCA's New GOAT (Conformer Search Tool), Docker, and Solvator Modules
Creators: name: de Souza, Bernardo
Publisher: name: Zenodo
Year: 2025

description: This workshop was run for the Virtual Winter School on Computational Chemistry

The format was a series of introductory lectures, followed by hands-on workshop sessions.

Information for new users of ORCA

To ensure a smooth and productive practical hands-on session, we kindly ask participants to complete the following preparations beforehand:

Install ORCAStudents should install ORCA in advance for the hands-on part of the workshop.- Installation Instructions: ORCA Installation Guide(Participants can register for free on the ORCA forum to download the software.)- ORCA Download: ORCA Download Page

Install Avogadro as a GUIWe recommend installing Avogadro as a graphical user interface for ORCA.- Installation Instructions: Avogadro Installation Guide

Install ChimeraX as a GUIWe also recommend installing ChimeraX as a graphical user interface for ORCA.- Installation Instructions: ChimeraX Installation Guide- Please also install the SEQCROW plugin! It can be installed via the Tools/More Tools menu within ChimeraX.
Novel Total Synthesis of Anserinone A and B
Creators: name: Whisenant, Jonathan
name: Vinson, Daniel
name: Blanco, Michael
name: Hughes, Carson
name: David, Samuel
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Anserinones A and B are natural products that have been shown to have potential anticancer, antifungal and antibacterial properties. This work entails the novel synthesis of these natural products.
HadISDH.marine Update Document version 1.5.0.2022f
Creators: name: Willett, Kate
Publisher: name: Zenodo
Year: 2024

description: Update notes for HadISDH.marine.1.5.0.2022f compared to the previous version. This describes any major changes, bug fixes and minor changes, and minor bug fixes and historical updates. It includes their justification and any notable impacts. 

Note that this version does not have a related dataset on the CEDA archive because it was an interim version rather than an annual update.
SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype
Creators: name: Bongiovanni, Dario
name: Klug, Melissa
name: Lazareva, Olga
name: Weidlich, Simon
name: Biasi, Marina
name: Ursu, Simona
name: Warth, Sarah
name: Buske, Christian
name: Lukas, Marina
name: Spinner, Christoph D.
name: Scheidt, Moritz Von
name: Condorelli, Gianluigi
name: Baumbach, Jan
name: Laugwitz, Karl-Ludwig
name: List, Markus
name: Bernlochner, Isabell
name: Dc.Contributor.Author
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Mechanisms of disease
subject: Viral infection
subject: ACUTE RESPIRATORY SYNDROME
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health

description: Abstract Novel coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable state, characterized by abnormal coagulation parameters and by increased incidence of cardiovascular complications. With this study, we aimed to investigate the activation state and the expression of transmembrane proteins in platelets of hospitalized COVID-19 patients. We investigated transmembrane proteins expression with a customized mass cytometry panel of 21 antibodies. Platelets of 8 hospitalized COVID-19 patients not requiring intensive care support and without pre-existing conditions were compared to platelets of healthy controls (11 donors) with and without in vitro stimulation with thrombin receptor-activating peptide (TRAP). Mass cytometry of non-stimulated platelets detected an increased surface expression of activation markers P-Selectin (0.67 vs. 1.87 median signal intensity for controls vs. patients, p = 0.0015) and LAMP-3 (CD63, 0.37 vs. 0.81, p = 0.0004), the GPIIb/IIIa complex (4.58 vs. 5.03, p < 0.0001) and other adhesion molecules involved in platelet activation and platelet–leukocyte interactions. Upon TRAP stimulation, mass cytometry detected a higher expression of P-selectin in COVID-19 samples compared to controls (p < 0.0001). However, we observed a significantly reduced capacity of COVID-19 platelets to increase the expression of activation markers LAMP-3 and P-Selectin upon stimulation with TRAP. We detected a hyperactivated phenotype in platelets during SARS-CoV-2 infection, consisting of highly expressed platelet activation markers, which might contribute to the hypercoagulopathy observed in COVID-19. In addition, several transmembrane proteins were more highly expressed compared to healthy controls. These findings support research projects investigating antithrombotic and antiplatelet treatment regimes in COVID-19 patients, and provide new insights on the phenotypical platelet expression during SARS-CoV-2 infection.
Flexible 3D-printed test rig for liquid distribution characterization of laboratory-scale packings
Creators: name: Ashour, Mohamed Adel
name: Neukäufer, Johannes
name: Sarajlic, Nadin
name: Klein, Harald
name: Rehfeldt, Sebastian
name: Paschold, Jürgen
name: Knösche, Carsten
name: Grützner, Thomas
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: 3D printing
subject: Miniaturization
subject: Structured packing
subject: DDC 620 / Engineering & allied operations
subject: Three-dimensional printing
subject: 3D-Druck
subject: Liquid distribution
subject: Maldistribution
subject: Miniaturisierung

description: In distillation, additive manufacturing can facilitate the design and fabrication of laboratory-scale packed columns that overcome the existing miniaturization limits while maintaining scalability. Liquid distribution is one of the appraisal criteria for new packing structures. For this purpose, a flexible 3D-printed laboratory test rig is presented. The setup offers a wide liquid load operation range from approx. 2.5 to 20 m3m−2h−1 for column diameters of 20–50 mm. First results regarding steady-state development, initial liquid distribution effect and liquid load variation are shown using a 3D-printed version of the Rombopak 9M in a 20-mm diameter column.
Challenges in transfer of gas-liquid reactions from batch to continuous operation : dimensional analysis and simulations for aerobic oxidation
Creators: name: Friedland, Jens
name: Güttel, Robert
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Multiphase reaction
subject: Mathematical modelling
subject: Liquid phase oxidation
subject: POM catalyst
subject: DDC 540 / Chemistry & allied sciences
subject: Flow chemistry
subject: Flüssiggas

description: The transfer of gas-liquid reactions from conventional batch processes into continuous operation using milli and micro reactors is claimed as an important step towards process intensification. Importantly, this transfer step should be realized in an early phase of process development, already, in order to minimize research efforts towards the undesired operation strategy. The main challenge of this approach, therefore, arises from lack of knowledge in the early stage of process development and the resulting system with high degrees of freedom. This contribution presents an approach to tackle this challenge by means of mathematical modelling and simulation for the aerobic oxidation of 9,10-dihydroanthracene (DHA) catalyzed by polyoxometalates (POMs) being used as example for gas-liquid reactions. The reaction was chosen as it provides sufficient complexity, since it consists of three consecutive oxidation steps of DHA and a parallel catalytic redox-cycle according to a Mars-van-Krevelen mechanism. It also provides the challenge of unknown reaction kinetics, which have been estimated in this contribution. The dimensionless balance equations for reactor modeling are derived and parametrized based on early stage experimental results obtained in batch operation mode. The discrimination between batch and continuous operation was performed by means of characteristic dimensionless numbers using the identical mathematical model for comparability reasons. The model was used to perform sensitivity studies with emphasis on the interplay between mass transfer characteristics and reaction kinetics for both the batch and continuous operation mode. The simulation results show that the performance of both operation modes mainly depend on the oxidation state of the POM catalyst, which is caused by the differences in oxygen availability. Therefore, results obtained in batch operation mode are prone to be masked by mass transfer issues, which affects catalyst and reactor development at the same time and may thus cause maldevelopments. With respect to process development it can thus be concluded that the transfer from batch to continuous operation together with mathematical modeling is important in an early phase, already, in order to detect limitations misleading the development. Finally, even simple models with roughly estimated parameters from preliminary experiments are shown to be sufficient in the early phase and can systematically be improved, in the subsequent phases.
Green synthesis of novel isatin thioketal derivatives under solvent-free conditions
Creators: name: Gholamhassan Imanzadeh
name: Alireza Banaei
name: Taarof Fathi
name: Soltanzadeh, Zahra
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology
subject: 60506 Virology

description: A new series of spiro[[1,3]dithiolane-2,3′-indolines]-2′-one derivatives was synthesized using Michael addition reaction of spiro[[1,3]dithiolane-2,3′-indolin]-2′-one to various α,β-unsaturated esters as well as direct alkylation of this compound with alkyl dihalides. Michael reaction of spiro[[1,3]dithiolane-2,3′-indolin]-2′-one and α,β-unsaturated esters produced related Michael adduct in the presence of tetrabutylammonium bromide and base 1,4-diazabicyclo[2.2.2]octane in good to excellent yields at 80°C under solvent-free conditions. Also, direct alkylation of spiro[[1,3]dithiolane-2,3′-indolin]-2′-one by dihaloalkanes in the presence of base K2CO3 afforded the corresponding products in good yields under the same conditions.
Synthesis and nanoscale characterization of hierarchically assembled molecular nanosheets
Creators: name: Richard‐Lacroix, Marie
name: Küllmer, Maria
name: Gaus, Anna‐Laurine
name: Neumann, Christof
name: Tontsch, Christian
name: Von Delius, Max
name: Deckert, Volker
name: Turchanin, Andrey
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: chemical functionalization
subject: hierarchical assembly
subject: molecular nanosheets
subject: tip‐enhanced Raman spectroscopy
subject: DDC 540 / Chemistry & allied sciences
subject: DDC 620 / Engineering & allied operations
subject: Raman spectroscopy
subject: Raman-Spektroskopie

description: Abstract Chemical functionalization of molecular 2D materials toward the assembly of hierarchical functional nanostructures is of great importance for nanotechnology including areas like artificial photocatalytic systems, nanobiosensors, or ultrafiltration. To achieve the desired functionality of 2D materials, these need to be characterized down to the nanoscale. However, obtaining the respective chemical information is challenging and generally requires the application of complementary experimental techniques. Here, the synthesis and chemical characterization of hierarchically assembled molecular nanosheets based on ≈1 nm thin, molecular carbon nanomembrane (CNM) and covalently grafted, single‐molecule layer cobalt(III) catalysts for the light‐driven hydrogen evolution reaction (HER) is demonstrated. X‐ray photoelectron spectroscopy (XPS) and tip‐enhanced Raman spectroscopy (TERS) to access both the transversal and longitudinal chemical information of the synthesized nanosheets with nanometer resolution are employed. TERS and XPS data provide detailed information on the average and local surface distribution of the catalyst as well as mechanistic details of the grafting reaction. The proposed approach represents a general route toward a nanoscale structural analysis for a variety of molecular 2D materials—a rapidly growing materials class with broad prospects for fundamental science and applications.
description: Hierarchically assembled nanosheets with ultimate molecular thickness, bearing functional cobalt(III) complexes are investigated by X‐ray photoelectron spectroscopy and tip‐enhanced Raman scattering. The combination of both techniques provides detailed insights into the structure of the formed 2D materials down to the nanoscale.
Wnt1 boosts fracture healing by enhancing bone formation in the fracture callus
Creators: name: Haffner‐Luntzer, Melanie
name: Ragipoglu, Deniz
name: Ahmad, Mubashir
name: Schoppa, Astrid
name: Steppe, Lena
name: Fischer, Verena
name: Luther, Julia
name: Yorgan, Timur
name: Bockamp, Ernesto
name: Amling, Michael
name: Schinke, Thorsten
name: Ignatius, Anita
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: WNT1
subject: FRACTURE HEALING
subject: BONE REGENERATION
subject: OSTEOPOROSIS
subject: OSTEOBLASTS
subject: MICE
subject: DEFECTS
subject: ROMOSOZUMAB
subject: HOMEOSTASIS
subject: MUTATIONS
subject: RHBMP-2
subject: PATHWAY
subject: DDC 610 / Medicine & health

description: AbstractDespite considerable improvement in fracture care, 5%–10% of all fractures still heal poorly or result in nonunion formation. Therefore, there is an urgent need to identify new molecules that can be used to improve bone fracture healing. One activator of the Wnt‐signaling cascade, Wnt1, has recently gained attention for its intense osteoanabolic effect on the intact skeleton. The aim of the present study was to investigate whether Wnt1 might be a promising molecule to accelerate fracture healing both in skeletally healthy and osteoporotic mice that display a diminished healing capacity. Transgenic mice for a temporary induction of Wnt1 specifically in osteoblasts (Wnt1‐tg) were subjected to femur osteotomy. Non‐ovariectomized and ovariectomized Wnt1‐tg mice displayed significantly accelerated fracture healing based on a strong increase in bone formation in the fracture callus. Transcriptome profiling revealed that Hippo/yes1‐associated transcriptional regulator (YAP)‐signaling and bone morphogenetic protein (BMP) signaling pathways were highly enriched in the fracture callus of Wnt1‐tg animals. Immunohistochemical staining confirmed increased activation of YAP1 and expression of BMP2 in osteoblasts in the fracture callus. Therefore, our data indicate that Wnt1 boosts bone formation during fracture healing via YAP/BMP signaling both under healthy and osteoporotic conditions. To further test a potential translational application of Wnt1, we applied recombinant Wnt1 embedded into a collagen gel during critical‐size bone‐defect repair. Mice treated with Wnt1 displayed increased bone regeneration compared to control mice accompanied by increased YAP1/BMP2 expression in the defect area. These findings are of high clinical relevance because they indicate that Wnt1 could be used as a new therapeutic agent to treat orthopedic complications in the clinic. © 2023 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).
Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat
Creators: name: Ahmad, Mubashir
name: Haffner-Luntzer, Melanie
name: Schoppa, Astrid
name: Najafova, Zeynab
name: Lukic, Teodora
name: Yorgan, Timur Alexander
name: Amling, Michael
name: Schinke, Thorsten
name: Ignatius, Anita
Publisher: name: Universität Ulm
Year: 2024
Subjects: subject: Age-related osteoporosis
subject: Osteoblast differentiation
subject: Plasminogen activator
subject: Post-menopausal osteoporosis
subject: Wnt1 signalin
subject: DDC 610 / Medicine & health
subject: DDC 570 / Life sciences

description: Physical activity-induced mechanical stimuli play a crucial role in preserving bone mass and structure by promoting bone formation. While the Wnt pathway is pivotal for mediating the osteoblast response to loading, the exact mechanisms are not fully understood. Here, we found that mechanical stimulation induces osteoblastic Wnt1 expression, resulting in an upregulation of key osteogenic marker genes, including Runx2 and Sp7, while Wnt1 knockdown using siRNA prevented these effects. RNAseq analysis identified Plat as a major target through which Wnt1 exerts its osteogenic influence. This was corroborated by Plat depletion using siRNA, confirming its positive role in osteogenic differentiation. Moreover, we demonstrated that mechanical stimulation enhances Plat expression, which, in turn leads to increased expression of osteogenic markers like Runx2 and Sp7. Notably, Plat depletion by siRNA prevented this effect. We have established that Wnt1 regulates Plat expression by activating β-Catenin. Silencing Wnt1 impairs mechanically induced β-Catenin activation, subsequently reducing Plat expression. Furthermore, our findings showed that Wnt1 is essential for osteoblasts to respond to mechanical stimulation and induce Runx2 and Sp7 expression, in part through the Wnt1/β-Catenin/Plat signaling pathway. Additionally, we observed significantly reduced Wnt1 and Plat expression in bones from ovariectomy (OVX)-induced and age-related osteoporotic mouse models compared with non-OVX and young mice, respectively. Overall, our data suggested that Wnt1 and Plat play significant roles in mechanically induced osteogenesis. Their decreased expression in bones from OVX and aged mice highlights their potential involvement in post-menopausal and age-related osteoporosis, respectively.
title: Kompetenzauffassung in sportwissenschaftlichen Sportmanagementstudiengängen aus Student*innensicht
titleType: Other
Creators: name: Kley, Theresa
name: Wicker, Pamela
Publisher: name: Deutsche Sporthochschule Köln
Year: 2021

description: In interdisziplinär angelegten, außerschulischen sportwissenschaftlichen Studiengängen mit Schwerpunkt Sportmanagement fehlt Student*innen ein konkretes Berufsbild und damit Orientierung zur notwendigen Profilierung. Die in diesen Studiengängen erworbenen Abschlüsse sollen Absolvent*innen für mögliche Berufsfelder wie Sportvereine/-verbände, kommerzielle Sportanbieter und öffentliche Sportinstitutionen qualifizieren. Somit gewinnt die Vermittlung fachlicher und überfachlicher Kompetenzen (Schlüsselkompetenzen) an Bedeutung, welche berufsübergreifend relevant sind. Allerdings setzen sich Student*innen zu Beginn des Studiums wenig mit dem Curriculum und den zu erwerbenden Kompetenzen auseinander. Vor diesem Hintergrund untersucht diese Studie das studentische Kompetenzverständnis im Sportmanagementstudium. Das theoretische Fundament bilden der akademische Kompetenzbegriff sowie unterschiedliche Niveaustufen der Kompetenzentwicklung. In der (inter)nationalen Literatur fehlt bisher eine differenzierte Betrachtung der Fach- und Schlüsselkompetenzen aus Sicht der Student*innen. In einer qualitativ angelegten Erhebung wurden 14 Student*innen eines universitären Sportmanagementstudiengangs (Bachelor) zum Erwerb fachlicher und überfachlicher Kompetenzen befragt. Die Ergebnisse zeigen, dass Student*innen ein vages Verständnis der fachlichen Kompetenzen haben, während sie den Erwerb der überfachlichen Schlüsselkompetenzen deutlicher benennen können. Außerdem verorten Student*innen die erfolgreiche Vermittlung der fachlichen Kompetenzen auf Seiten der Universitäten, während sie sich selbst in der Verantwortung sehen, die Schlüsselkompetenzen im Verlauf des Studiums zu entwickeln. Student*innen mit bereits abgeschlossener Ausbildung gehen von einem geringeren Erwerb von Schlüsselkompetenzen im Studium aus. Die Ergebnisse der Studie liefern Implikationen für die Schwerpunktsetzung und Fokussierung von Kompetenzen in der Curricular-Gestaltung und Lehrpraxis.
Quantifying water stress effect on daily light use efficiency in Mediterranean ecosystems using satellite data
Creators: name: Sanchez-Ruiz, Sergio
name: Moreno, Alvaro
name: Piles, Maria
name: Maselli, Fabio
name: Carrara, Arnaud
name: Running, Steven
name: Gilabert, Maria Amparo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Space Science
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences

description: The capacity of six water stress factors (ε′i) to track daily light use efficiency (ε) of water-limited ecosystems was evaluated. These factors are computed with remote sensing operational products and a limited amount of ground data: ε′1 uses ground precipitation and air temperature, and satellite incoming global solar radiation; ε′2 uses ground air temperature, and satellite actual evapotranspiration and incoming global solar radiation; ε′3 uses satellite actual and potential evapotranspiration; ε′4 uses satellite soil moisture; ε′5 uses satellite-derived photochemical reflectance index; and ε′6 uses ground vapor pressure deficit. These factors were implemented in a production efficiency model based on Monteith’s approach in order to assess their performance for modeling gross primary production (GPP). Estimated GPP was compared to reference GPP from eddy covariance (EC) measurements (GPPEC) in three sites placed in the Iberian Peninsula (two open shrublands and one savanna). ε′i were correlated to ε, which was calculated by dividing GPPEC by ground measured photosynthetically active radiation (PAR) and satellite-derived fraction of absorbed PAR. Best results were achieved by ε′1, ε′2, ε′3 and ε′4 explaining around 40% and 50% of ε variance in open shurblands and savanna, respectively. In terms of GPP, R2 ≈ 0.70 were obtained in these cases.
Attitudes towards disclosing a mental illness : impact on quality of life and recovery
Creators: name: Mayer, Lea
name: Corrigan, Patrick W.
name: Eisheuer, Daniela
name: Öxle, Nathalie
name: Rüsch, Nicolas
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Mental illness stigma
subject: Disclosure attitudes
subject: Recovery
subject: Attitudes to disclosure questionnaire
subject: DDC 150 / Psychology
subject: Mentally ill persons
subject: Mental disorders
subject: Prejudice
subject: Social stigma
subject: Disclosure
subject: Quality of life
subject: Psychisch Kranker
subject: Psychische Störung
subject: Stigmatisierung
subject: Selbstöffnung
subject: Lebensqualität

description: Purpose The decision whether to disclose a mental illness has individual and social consequences. Secrecy may protect from stigma and discrimination while disclosure can increase social support and facilitate help-seeking. Therefore, disclosure decisions are a key reaction to stigma. The first aim of this study was to test a newly developed scale to measure disclosure attitudes, the Attitudes to Disclosure Questionnaire (AtDQ). The second aim was to examine the impact of attitudes towards disclosing a mental illness on quality of life and recovery. Methods Among 100 participants with mental illness, disclosure attitudes, quality of life, recovery, benefits of disclosure, secrecy, social withdrawal, self-stigma, and depressive symptoms were assessed at weeks 0, 3 and 6. Psychometric properties of the AtDQ were analysed. Longitudinal associations between disclosure attitudes at baseline and quality of life and recovery after 6 weeks were examined in linear regressions. Results The analyses of the AtDQ indicated one-factor solutions, high acceptability, high internal consistency, and good retest reliability for the total scale and the subscales as well as high construct validity of the total scale. Results provided initial support for sensitivity to change. More positive disclosure attitudes in general and in particular regarding to family at baseline predicted better quality of life and recovery after 6 weeks. Conclusion The current study provides initial support for the AtDQ as a useful measure of disclosure attitudes. Disclosing a mental illness, especially with respect to family, may improve quality of life and recovery of people with mental illness.
Social class and educational opportunity: exploring the experiences of undergraduate university students studying Physical Education and Sports Pedagogy
Creators: name: Hobson, Michael
Publisher: name: Loughborough University
Year: 2022
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences

description: This thesis critically explores the impact of social class and physical capital upon the prior socialisation and subsequent experiences of undergraduate students studying Physical Education and Sport Pedagogy (PESP). In particular the thesis scrutinises the extent which social class impacted the fields of family, school, and sport in cultivating the dispositions students entered university with. It explores how these dispositions intersected with students’ material circumstances, and their subsequent ability to navigate both the academic and social fields within the university. The study utilised a case study of undergraduate students studying PESP at Summer Heights University (pseudonym), a post-92 university situated in an affluent suburb in the Southeast of England. Utilising a mixture of life-history and semi-structured interviews conducted in semester two of their second year as undergraduate students and one year after graduating. Participants were purposefully sampled to reflect a range of different social classes, and levels of physical capital to provide data pertaining to the varied classed experiences of students. The subsequent analysis illuminated several key areas highlighting the different dispositions students entered their degree course with and the resulting impact of social class upon students’ experiences. As a result of the process of data analysis, interpreted through a framework inspired by Bourdieusian theorising, this thesis developed several unique themes which provide an original contribution to the study of social class and higher education in the UK. These provide a nuanced insight into how mechanisms in family, schools, and sport shape the specific dispositions students entered HE with; highlighting the roles which modelling of behaviour by parents, the geo-demography of the schools and colleges students attended, and the individual knowledge, skills and networks participants entered HE with. Furthermore, it became apparent that students perceived academic staff to attribute symbolic value to behaviours loosely associated with notions of independent learning and professionalism gained from experiences in the PESP field but noted that these often failed to consider differences in student’s social networks and material conditions. Finally, it was evident that classed patterns were apparent in relation to students' engagement in social activities within the university. However, it appeared that these patterns were not simply devised along classed lines, with factors such as commuting or living in university accommodation, ethnicity, and students' external commitments all impacting their experiences.
Massive parallel sequencing of human whole mitochondrial genomes with Ion Torrent technology: an optimized workflow for Anthropological and Population Genetics studies
Creators: name: Fanti, Sara De
name: Vianello, Dario
name: Giuliani, Cristina
name: Quagliariello, Andrea
name: Cherubini, Anna
name: Sevini, Federica
name: Iaquilano, Nicoletta
name: Franceschi, Claudio
name: Sazzini, Marco
name: Luiselli, Donata
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Investigation of human mitochondrial DNA variation patterns and phylogeny has been extensively used in Anthropological and Population Genetics studies and sequencing the whole mitochondrial genome is progressively becoming the gold standard. Among the currently available massive parallel sequencing technologies, Ion Torrent™ semiconductor sequencing represents a promising approach for such studies. Nevertheless, an experimental protocol conceived to enable the achievement of both as high as possible yield and of the most homogeneous sequence coverage through the whole mitochondrial genome is still not available. The present work was thus aimed at improving the overall performance of whole mitochondrial genomes Ion Torrent™ sequencing, with special focus on the capability to obtain robust coverage and highly reliable variants calling. For this purpose, a series of cost-effective modifications in standard laboratory workflows was fine-tuned to optimize them for medium- and large-scale population studies. A total of 54 human samples were thus subjected to sequencing of the whole mitochondrial genome with the Ion Personal Genome Machine™ System in four distinct experiments and using Ion 314 chips. Seven of the selected samples were also characterized by means of conventional Sanger sequencing for the sake of comparison. Obtained results demonstrated that the implemented optimizations had definitely improved sequencing outputs in terms of both variants calling efficiency and coverage uniformity, enabling to setup an effective and accurate protocol for whole mitochondrial genome sequencing and a considerable reduction in experimental time consumption and sequencing costs.
Stress events and changes in dysfunctional attitudes and automatic thoughts following recovery from depression in inpatient psychotherapy : mediation analyses with longitudinal data
Creators: name: Rojas, Roberto
name: Behnke, Alexander
name: Hautzinger, Martin
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Major depression
subject: Relapse/recurrence
subject: Stress
subject: Dysfunctional attitudes
subject: Automatic thoughts
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Depression
subject: Stress, Psychological
subject: Depression
subject: Stress

description: Background Stressful event exposure, dysfunctional attitudes (DA), negative automatic thoughts (NAT), and declining positive automatic thoughts (PAT) have been associated with depressive relapse/recurrence. Few studies have investigated the course of these variables and their relevance for relapse/recurrence in remitted depression. Methods Following successful inpatient treatment, in 39 remitted depressive patients, stressful events, DA, NAT, PAT, and depressive relapse/recurrence were assessed five times during a 16-month follow-up. Data were analyzed with mixed effect models, and mediation effects were tested. Results Stressful events after discharge correlated with depressive relapse/recurrence. This association was mainly mediated by a stress-related decline of PAT within four months post discharge. Patients’ DA were relatively stable during the observation period and did not depend on stressful events, indicating DA as a risk trait for depressive relapse/recurrence. Mediation analyses revealed that independent of stress, DA were linked to depressive relapse/recurrence through more NAT. Conclusion Our findings suggest stressful events evoke relapse/recurrence in remitted depression through rapid deterioration of PAT after discharge from inpatient therapy. DA are expressed through NAT which additionally contribute to higher risk of depressive relapse/recurrence. Consequently, maintenance therapy requires techniques to promote the maintenance of PAT, and to effectively restructure DA and NAT.
title: OFROM: interview avec unine15a51m
Creators: name: Delafontaine, François
name: Renggli, Laura
Publisher: name: COCOON - https://cocoon.huma-num.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023
Subjects: subject: Français
subject: fra

description: Conforms to: Praat textgrid
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Conforms to: doi:10.34847/cocoon.69c4fa74-f324-3ddb-9f1a-580867fd5826
description: Source: https://nakala.fr/10.34847/nkl.583craqk.v2#f1d7c88dbc112cdbab42ccfb6d57b84494a0cb10
Mental health workers’ perspectives on peer support in high-, middle- and low income settings: a focus group study
Creators: name: Krumm, Silvia
name: Haun, Maria
name: Hiller, Selina
name: Ashleigh, Charles
name: Kalha, Jasmine
name: Niwemuhwezi, Jackie
name: Nixdorf, Rebecca
name: Puschner, Bernd
name: Ryan, Grace
name: Shamba, Donat
name: Garber Epstein, Paula
name: Moran, Galia
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: Peer support
subject: Mental health workers
subject: High-, middle- and low income settings
subject: Focus groups
subject: DDC 150 / Psychology
subject: Mental health services
subject: Peer group
subject: Psychiatrische Versorgung
subject: Peer-Group

description: Background Peer support is increasingly acknowledged as an integral part of mental health services around the world. However, most research on peer support comes from high-income countries, with little attention to similarities and differences between different settings and how these affect implementation. Mental health workers have an important role to play in integrating formal peer support into statutory services, and their attitudes toward peer support can represent either a barrier to or facilitator of successful implementation. Thus, this study investigates mental health workers’ attitudes toward peer support across a range of high- (Germany, Israel), middle- (India), and low-income country (Tanzania, Uganda) settings. Methods Six focus groups were conducted in Ulm and Hamburg (Germany), Butabika (Uganda), Dar es Salaam (Tanzania), Be’er Sheva (Israel), and Ahmedabad, Gujarat (India) with a total of 35 participants. Transcripts were analyzed using thematic content analysis. Results Participants across the study sites demonstrated overall positive attitudes towards peer support in mental health care, although some concerns were raised on potentially harmful effects of peer support such as negative role modelling and giving inadequate advice to service users. Notably, mental health workers from low- and middle-income countries described peer support workers as bridge-builders and emphasized the mutual benefits of peer support. Mental health workers’ views on peer support workers’ roles and role boundaries differed between sites. In some settings, mental health workers strongly agreed on the need for role clarity, whereas in others, mental health workers expressed mixed views, with some preferring blurred role boundaries. Regarding collaboration, mental health workers described peer support workers as supporters and utilizers, equal partners or emphasized a need for trust and commitment. Conclusions Mental health workers’ attitudes toward peer support workers were positive overall, but they also varied depending on local context, resources and previous experiences with peer support. This affected their conceptions of peer support workers’ roles, role clarity, and collaboration. This study demonstrated that reconciling the need for local adaptations and safeguarding the core values of peer support is necessary and possible, especially when the implementation of recovery-oriented interventions such as peer support is accelerating worldwide.
Accelerating the Adoption of Research Data Management Strategies in Materials Science: Best Practices and Collaboration Hub©
Creators: name: Medina, Johanne Gren Duhay
Publisher: name: Manara - Qatar Research Repository
Year: 2024
Subjects: classificationCode: 40
subject: Engineering

description: The need for good research data management (RDM) practices is becoming more recognized as a critical part of research attributed to the exponential rise in Big Data. The materials science community is no exception to this trend, as it embarks on a new paradigm of data-driven science, leveraging artificial intelligence to expedite materials discovery, but necessitating large-scale datasets to perform effectively. Hence, there is a concerted effort to standardize, curate, preserve, and disseminate these materials data in a manner that adheres to the Findable, Accessible, Interoperable, and Reusable (FAIR) guiding principles. This thesis work offers two core contributions in this regard including the recommendation of best practices within the data-driven materials research life cycle to develop and/or procure an effective and FAIR RDM system. These best practices are then applied to develop a data sharing platform dubbed Collaboration Hub © for catalysis surface reactions which are computationally expensive and valuable. This platform consists of a MongoDB database, Python FastAPI, and a React JS website, all bundled up within Docker containers and deployed on secure servers with the purpose to facilitate the long-term use and preservation of FAIR and sustainable data.
Stability and Instability of Equilibria in Age-Structured Diffusive Populations
Creators: name: Walker, Christoph
Publisher: name: New York, NY [u.a.] : Springer Science + Business Media B.V.
Year: 2024
Subjects: subject: Age structure
subject: Diffusion
subject: Linearization
subject: Semigroups
subject: Stability of equilibria
subject: Dewey Decimal Classification::500 | Naturwissenschaften::510 | Mathematik

description: The principle of linearized stability and instability is established for a classical model describing the spatial movement of an age-structured population with nonlinear vital rates. It is shown that the real parts of the eigenvalues of the corresponding linearization at an equilibrium determine the latter’s stability or instability. The key ingredient of the proof is the eventual compactness of the semigroup associated with the linearized problem, which is derived by a perturbation argument. The results are illustrated with examples.
Sixfolds of generalized Kummer type and K3 surfaces
Creators: name: Floccari, Salvatore
Publisher: name: Cambridge : Cambridge Univ. Press
Year: 2024
Subjects: subject: Hodge conjecture
subject: hyper-Kähler varieties
subject: K3 surfaces
subject: Dewey Decimal Classification::500 | Naturwissenschaften::510 | Mathematik

description: We prove that any hyper-Kähler sixfold K of generalized Kummer type has a naturally associated manifold YK of K3[3] type. It is obtained as crepant resolution of the quotient of K by a group of symplectic involutions acting trivially on its second cohomology. When K is projective, the variety YK is birational to a moduli space of stable sheaves on a uniquely determined projective K3 surface SK. As an application of this construction we show that the Kuga–Satake correspondence is algebraic for the K3 surfaces SK, producing infinitely many new families of K3 surfaces of general Picard rank 16 satisfying the Kuga–Satake Hodge conjecture.