cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of XSMILES: interactive visualization for molecules, SMILES and XAI attribution scores
Creators: name: Heberle, Henry
name: Zhao, Linlin
name: Schmidt, Sebastian
name: Wolf, Thomas
name: Heinrich, Julian
Publisher: name: figshare
Year: 2023
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences
subject: Information Systems

description: Additional file 1. Additional information for Use case 2.
Single Electron Dynamics of an Atomic Silicon Quantum Dot on the H-Si(100) 2x1 Surface
Creators: name: Taucer, Marco
name: Livadaru, Lucian
name: Piva, Paul G.
name: Achal, Roshan
name: Labidi, Hatem
name: Pitters, Jason L.
name: Wolkow, Robert A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Here we report the direct observation of single electron charging of a single atomic Dangling Bond (DB) on the H-Si(100) 2x1 surface. The tip of a scanning tunneling microscope is placed adjacent to the DB to serve as a single electron sensitive charge-detector. Three distinct charge states of the dangling bond, positive, neutral, and negative, are discerned. Charge state probabilities are extracted from the data, and analysis of current traces reveals the characteristic single electron charging dynamics. Filling rates are found to decay exponentially with increasing tip-DB separation, but are not a function of sample bias, while emptying rates show a very weak dependence on tip position, but a strong dependence on sample bias, consistent with the notion of an atomic quantum dot tunnel coupled to the tip on one side and the bulk silicon on the other.
description: 7 pages, 6 figures
Protokoll der Mitgliederversammlung vom 6. Juli 2017
Creators: name: Arndt, Betty
name: Müller, Ulrich
Publisher: name: Mitteilungen der Deutschen Gesellschaft für Archäologie des Mittelalters und der Neuzeit
Year: 2018

description: Mitteilungen der Deutschen Gesellschaft für Archäologie des Mittelalters und der Neuzeit, Bd. 31 (2018): Mitteilungen der DGAMN: Archäologie des Glaubens - Umbrüche und Konflikte
Else Roesdahl / Søren M. Sindbæk / Anne Pedersen / David M. Wilson, Aggersborg. The Viking-Age Settlement and Fortress
Creators: name: Kleingärtner, Sunhild
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2018

description: Rezension zu: Else Roesdahl / Søren M. Sindbæk / Anne Pedersen / David M. Wilson, Aggersborg. The Viking-Age Settlement and Fortress. Jutland Archaeological Society Publications Band 82. Jutland Archaeological Society, Højbjerg 2014. ISBN 978-87-88415-87-2. 478 Seiten
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 95 (2017)
Arthur Asa Berger, What Objects Mean: An Introduction to Material Culture / Stefanie Samida / Manfred K. Eggert / Hans Peter Hahn (Hrsg.), Handbuch Materielle Kultur. Bedeutungen, Konzepte, Disziplinen
Creators: name: Müller, Ulrich
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2018

description: Rezension zu: Arthur Asa Berger, What Objects Mean: An Introduction to Material Culture. 2. Ausgabe. Left Coast Press, Walnut Creek 2014. £ 21,99. ISBN 978-1-61132-904-9 (Softcover). ISBN 978-1-61132-906-3 (E-Book). 272 Seiten mit zahlreichen Abbildungen

Stefanie Samida / Manfred K. Eggert / Hans Peter Hahn (Hrsg.), Handbuch Materielle Kultur. Bedeutungen, Konzepte, Disziplinen. J. B. Metzler Verlag, Stuttgart, Weimar 2014. ISBN 978-3-476-02464-0 (Hardcover). ISBN 978-3-476-05346-6 386 (E-Book). 378 Seiten
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 95 (2017)
Measuring Differences of Interpretation among Dentists on Antibiotic Prophylaxis Guidelines
Creators: name: Jacobucci, Jennifer Bereckis
Publisher: name: University of Illinois at Chicago
Year: 2021
Subjects: Uncategorized

description: Aim: To determine if the 2007 American Heart Association guidelines for dentists' prescription of prophylactic antibiotics guarding against bacterial endocarditis, which are based on gingival manipulation, are applied consistently by dental faculty. Methods: An emailed survey was conducted of U.S. and Canadian dental faculty regarding which of 24 dental procedures require gingival manipulation and which require prophylactic antibiotics. Confidence intervals were calculated for the proportion of subjects who considered gingival manipulation part of a procedure. If the confidence interval included 75%, we deemed it a consensus. Similarly, we calculated confidence intervals for whether subjects would prescribe antibiotics, and deemed 75% to be a consensus. Results: 122 subjects responded to the survey. No response rate could be calculated. Faculty reached consensus on prescribing for 66% of procedures. For gingival manipulation, consensus was achieved for 83% of the procedures. Conclusion: The lack of concordance between the two categories suggests that the 2007 guidelines are unclear for the dental faculty members. This conclusion likely extends to all dentists.
Crystal-field ground state of the orthorhombic Kondo insulator CeRu2Al10
Creators: name: Strigari, F.
name: Willers, T.
name: Muro, Y.
name: Yutani, K.
name: Takabatake, T.
name: Hu, Z.
name: Chin, Y. -Y.
name: Agrestini, S.
name: Lin, H. -J.
name: Chen, C. T.
name: Tanaka, A.
name: Haverkort, M. W.
name: Tjeng, L. H.
name: Severing, A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We have succeeded in establishing the crystal-field ground state of CeRu2Al10, an orthorhombic intermetallic compound recently identified as a Kondo insulator. Using polarization dependent soft x-ray absorption spectroscopy at the Ce M4,5 edges, together with input from inelastic neutron and magnetic susceptibility experiments, we were able to determine unambiguously the orbital occupation of the 4f shell and to explain quantitatively both the measured magnetic moment along the easy a axis and the small ordered moment along the c-axis. The results provide not only a platform for a realistic modeling of the spin and charge gap of CeRu2Al10, but demonstrate also the potential of soft x-ray absorption spectroscopy to obtain information not easily accessible by neutron techniques for the study of Kondo insulators in general.
description: submitted to Physical Review B Rapid Communications
Distribution of Schmidt-like eigenvalues for Gaussian Ensembles of the Random Matrix Theory
Creators: name: Pato, M. P.
name: Oshanin, G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We analyze the form of the probability distribution function P_{n}^{(β)}(w) of the Schmidt-like random variable w = x_1^2/(\sum_{j=1}^n x^{2}_j/n), where x_j are the eigenvalues of a given n \times n β-Gaussian random matrix, βbeing the Dyson symmetry index. This variable, by definition, can be considered as a measure of how any individual eigenvalue deviates from the arithmetic mean value of all eigenvalues of a given random matrix, and its distribution is calculated with respect to the ensemble of such β-Gaussian random matrices. We show that in the asymptotic limit n \to \infty and for arbitrary βthe distribution P_{n}^{(β)}(w) converges to the Marčenko-Pastur form, i.e., is defined as P_{n}^{(β)}(w) \sim \sqrt{(4 - w)/w} for w \in [0,4] and equals zero outside of the support. Furthermore, for Gaussian unitary (β= 2) ensembles we present exact explicit expressions for P_{n}^{(β=2)}(w) which are valid for arbitrary n and analyze their behavior.
description: 10 pages, 1 figure, submitted to JSTAT
The role of shared medical appointments in the management of chronic disease: utilising international experiences to design an intervention for peripheral arterial disease in the NHS
Creators: name: Morbi, Abigail Huseina Marguerite
Publisher: name: Imperial College London
Year: 2021

description: With over 15 million people living with chronic disease in England alone, patients and healthcare systems face significant burden, in terms of symptoms, quality-of-life and resource costs. One such chronic disease is peripheral arterial disease (PAD), with an estimated UK prevalence of 7%. Patients with PAD often have co-morbidities and require risk factor modification, having increased risk of cardiovascular morbidity and mortality. They utilise primary care, community and hospital resources, requiring multi-disciplinary team input, to provide lifestyle, medical and surgical management. With increasing prevalence of chronic disease and in the current economic climate, there is a need to empower patients to take an active role in their care and improve utilisation of existing healthcare resources. Interventions that streamline patient pathways, integrate the multi-disciplinary team and facilitate self-care are likely to benefit patients and the NHS. Shared medical appointments (SMAs) can improve patient education, self-management and clinical outcomes in those with chronic disease, whilst delivering care more efficiently. Whilst their use has increased in countries such as USA across a variety of settings, research or use within the NHS has mainly been within primary care. To date, SMAs have not been used within vascular surgery, in the UK or abroad. Using the example of PAD, this thesis seeks to investigate the role for SMAs in the NHS. Firstly, it identifies scope for improvement within current care. Through international collaboration, it then examines barriers and facilitators to implementing SMAs and the patient experience of this model of care. It details a co-design process, whereby UK patients and healthcare professionals were brought together to work with qualitative data from the preceding chapters. The final data chapters describe a pilot SMA and discuss experiences of staff and patients involved. Finally, the thesis reflects on implications of this work for clinical practice and healthcare policy.
Additional file 1 of Safety and efficacy of first-in-man intrathecal injection of human astrocytes (AstroRx®) in ALS patients: phase I/IIa clinical trial results
Creators: name: Gotkine, Marc
name: Caraco, Yoseph
name: Lerner, Yossef
name: Blotnick, Simcha
name: Wanounou, Maor
name: Slutsky, Shalom Guy
name: Chebath, Judith
name: Kuperstein, Graciela
name: Estrin, Elena
name: Ben-Hur, Tamir
name: Hasson, Arik
name: Molakandov, Kfir
name: Sonnenfeld, Tehila
name: Stark, Yafit
name: Revel, Ariel
name: Revel, Michel
name: Izrael, Michal
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 1. Supplementary materials and methods.
Diterpenoid alkaloids from two species of Delphinium
Creators: name: Huang, Shuai
name: Wang, Jian-Zhu
name: Guo, Qiu-Ju
name: Xiao, Yan
name: Feng, Yu-Ming
name: Chen, Lin
name: Xie, Jiang
name: Zhou, Xian-Li
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Four new compounds (1–4) were isolated from the whole plants of two species of Delphinium, including two C20-diterpenoid alkaloids, umbrodines A and B (1 and 2), and a dibenzoxazepinone, umbrolide A (3) from Delphinium umbrosum Hand.-Mazz. and a C20-diterpenoid alkaloid, kingiadine (4) from Delphinium kingianum Bruhl. ex Huth. Ten known diterpenoid alkaloids were also isolated. Their structures were elucidated via HR-ESIMS, IR, and NMR data. Lycoctonine (11) and delectinine (12) exhibited appreciable cardiac activity. Furthermore, 11 and 12 showed cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells, with the maximum protection rates of 61.63% and 51.18%, respectively.
On the origin of the B-stars in the Galactic center
Creators: name: Madigan, Ann-Marie
name: Pfuhl, Oliver
name: Levin, Yuri
name: Gillessen, Stefan
name: Genzel, Reinhard
name: Perets, Hagai B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a new directly-observable statistic which uses sky position and proper motion of stars near the Galactic center massive black hole to identify populations with high orbital eccentricities. It is most useful for stars with large orbital periods for which dynamical accelerations are difficult to determine. We apply this statistic to a data set of B-stars with projected radii 0."1 < p < 25" (~0.004 - 1 pc) from the massive black hole in the Galactic center. We compare the results with those from N-body simulations to distinguish between scenarios for their formation. We find that the scenarios favored by the data correlate strongly with particular K-magnitude intervals, corresponding to different zero-age main-sequence (MS) masses and lifetimes. Stars with 14 < mK < 15 (15 - 20 solar masses, t_{MS} = 8-13 Myr) match well to a disk formation origin, while those with mK > 15 (<15 solar masses, t_{MS} >13 Myr), if isotropically distributed, form a population that is more eccentric than thermal, which suggests a Hills binary-disruption origin.
description: Updated paper. 21 pages, 28 figures, 6 tables, ApJ accepted
Augmented reality for computer assisted orthopaedic surgery
Creators: name: Iqbal, Hisham
Publisher: name: Imperial College London
Year: 2022

description: In recent years, computer-assistance and robotics have established their presence in operating theatres and found success in orthopaedic procedures. Benefits of computer assisted orthopaedic surgery (CAOS) have been thoroughly explored in research, finding improvements in clinical outcomes, through increased control and precision over surgical actions. However, human-computer interaction in CAOS remains an evolving field, through emerging display technologies including augmented reality (AR) – a fused view of the real environment with virtual, computer-generated holograms. Interactions between clinicians and patient-specific data generated during CAOS are limited to basic 2D interactions on touchscreen monitors, potentially creating clutter and cognitive challenges in surgery. Work described in this thesis sought to explore the benefits of AR in CAOS through: an integration between commercially available AR and CAOS systems, creating a novel AR-centric surgical workflow to support various tasks of computer-assisted knee arthroplasty, and three pre–clinical studies exploring the impact of the new AR workflow on both existing and newly proposed quantitative and qualitative performance metrics. Early research focused on cloning the (2D) user-interface of an existing CAOS system onto a virtual AR screen and investigating any resulting impacts on usability and performance. An infrared-based registration system is also presented, describing a protocol for calibrating commercial AR headsets with optical trackers, calculating a spatial transformation between surgical and holographic coordinate frames. The main contribution of this thesis is a novel AR workflow designed to support computer-assisted patellofemoral arthroplasty. The reported workflow provided 3D in-situ holographic guidance for CAOS tasks including patient registration, pre-operative planning, and assisted-cutting. Pre-clinical experimental validation on a commercial system (NAVIO®, Smith & Nephew) for these contributions demonstrates encouraging early-stage results showing successful deployment of AR to CAOS systems, and promising indications that AR can enhance the clinician’s interactions in the future. The thesis concludes with a summary of achievements, corresponding limitations and future research opportunities.
On the Robust Optimal Stopping Problem
Creators: name: Bayraktar, Erhan
name: Yao, Song
Publisher: name: arXiv
Year: 2013
Subjects: subject: Probability (math.PR)
subject: Systems and Control (eess.SY)
subject: Optimization and Control (math.OC)
subject: Pricing of Securities (q-fin.PR)
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Economics and business
subject: 60G40, 93E20, 49L20, 91A15, 60G44, 91B28

description: We study a robust optimal stopping problem with respect to a set $\cP$ of mutually singular probabilities. This can be interpreted as a zero-sum controller-stopper game in which the stopper is trying to maximize its pay-off while an adverse player wants to minimize this payoff by choosing an evaluation criteria from $\cP$. We show that the \emph{upper Snell envelope $\ol{Z}$} of the reward process $Y$ is a supermartingale with respect to an appropriately defined nonlinear expectation $\ul{\sE}$, and $\ol{Z}$ is further an $\ul{\sE}-$martingale up to the first time $\t^*$ when $\ol{Z}$ meets $Y$. Consequently, $\t^*$ is the optimal stopping time for the robust optimal stopping problem and the corresponding zero-sum game has a value. Although the result seems similar to the one obtained in the classical optimal stopping theory, the mutual singularity of probabilities and the game aspect of the problem give rise to major technical hurdles, which we circumvent using some new methods.
description: Final Version, 50 pages. This is a much more comprehensive version of what appeared in the SIAM Journal on Control and Optimization
Additional file 2 of Safety and efficacy of first-in-man intrathecal injection of human astrocytes (AstroRx®) in ALS patients: phase I/IIa clinical trial results
Creators: name: Gotkine, Marc
name: Caraco, Yoseph
name: Lerner, Yossef
name: Blotnick, Simcha
name: Wanounou, Maor
name: Slutsky, Shalom Guy
name: Chebath, Judith
name: Kuperstein, Graciela
name: Estrin, Elena
name: Ben-Hur, Tamir
name: Hasson, Arik
name: Molakandov, Kfir
name: Sonnenfeld, Tehila
name: Stark, Yafit
name: Revel, Ariel
name: Revel, Michel
name: Izrael, Michal
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 2: Figure S1. ALSFRS-R slope for each patient in run-in, and 3-, 6- and 12-month follow up after AstroRx® treatment. Figure S2. Serum levels of Nfl for each patient. Table S1. List of serious TEAEs. Table S2. Treatment emergent adverse events (TEAE) reported in at least 20% of patients in both treatment arms. Table S3. AEs related to IT injection of AstroRx cells by lumbar puncture. Table S4. AEs related to immunosuppression by Mycophenolate Mofetil. Table S5. Slope analysis of handheld dynamometer megascore. Table S6. %SVC slopes analysis in run-in, and 3-, 6- and 12-month follow up after AstroRx® treatment
Ausgrabungen auf einem neolithisch-bronzezeitlichen Siedlungsplatz bei Bliedersdorf, Ldkr. Stade
Creators: name: Nelson, Hildegard
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2018

description: -
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 59 (1990): Nachrichten aus Niedersachsens Urgeschichte
Observation and measurement of "giant" dispersive optical non-linearities in an ensemble of cold Rydberg atoms
Creators: name: Parigi, Valentina
name: Bimbard, Erwan
name: Stanojevic, Jovica
name: Hilliard, Andrew J.
name: Nogrette, Florence
name: Tualle-Brouri, Rosa
name: Ourjoumtsev, Alexei
name: Grangier, Philippe
Publisher: name: arXiv
Year: 2012
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We observe and measure dispersive optical non-linearities in an ensemble of cold Rydberg atoms placed inside an optical cavity. The experimental results are in agreement with a simple model where the optical non-linearities are due to the progressive appearance of a Rydberg blockaded volume within the medium. The measurements allow a direct estimation of the "blockaded fraction" of atoms within the atomic ensemble.
Kaiserzeitliche Siedlungsplätze in Hülsen/Westen, Gde. Dörverden, Ldkr. Verden - die Ausgrabungen 1989
Creators: name: Nowatzyk, Gabriele
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2018

description: -
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 59 (1990): Nachrichten aus Niedersachsens Urgeschichte
Frank Berger, Die Münzen der Römischen Republik im Kestner-Museum Hannover
Creators: name: Wulf, Friedrich-Wilhelm
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2018

description: Rezension zu: Frank Berger, Die Münzen der Römischen Republik im Kestner-Museum Hannover. — Herausgegeben vom Kestner-Museum, Sammlungskatalog 7. Hannover 1989. 539 Seiten, 3952 zweifache Fotoabbildungen. ISBN 3-924029-12-1.
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 59 (1990): Nachrichten aus Niedersachsens Urgeschichte
A Successful Broad-band Survey for Giant Lya Nebulae II: Spectroscopic Confirmation
Creators: name: Prescott, Moire K. M.
name: Dey, Arjun
name: Jannuzi, Buell T.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Using a systematic broad-band search technique, we have carried out a survey for large Lya nebulae (or Lya "blobs") at 2
description: Accepted to ApJ; 16 pages in emulateapj format; 8 figures, 3 tables
On Branching Ratios of $B_s$ Decays and the Search for New Physics in $B^0_s\to μ^+μ^-$
Creators: name: Fleischer, Robert
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The LHCb experiment has recently established a sizable width difference between the mass eigenstates of the $B_s$-meson system. This phenomenon leads to a subtle difference at the 10% level between the experimental branching ratios of $B_s$ decays extracted from time-integrated, untagged data samples and their theoretical counterparts. Measuring the corresponding effective $B_s$-decay lifetimes, both branching ratio concepts can be converted into each other. The rare decay $B^0_s\to μ^+μ^-$ and the search for New Physics through this channel is also affected by this effect, which enhances the Standard-Model reference value of the branching ratio by O(10%), while the effective lifetime offers a new observable to search for physics beyond the Standard Model that is complementary to the branching ratio.
description: 6 pages, invited talk at the 4th Workshop on Theory, Phenomenology and Experiments in Heavy Flavour Physics, Capri, Italy, 11-13 June 2012, to appear in the Proceedings
Bioinformatic and bioenergetic studies on the evolution of photosystem II
Creators: name: Oliver, Thomas
Publisher: name: Imperial College London
Year: 2022

description: Photosystem II (PSII) is the only enzyme in nature capable of catalysing the oxidation of water. Despite its ubiquity in plants, algae, and cyanobacteria, water oxidation has only evolved once, in an ancestor to the cyanobacterial phylum. How and when this occurred is unknown, but many hypotheses exist, with no clear consensus. Here, the evolution of PSII, and its bioenergetics, were investigated using a bioinformatic and biophysical approach. The heterodimeric reaction centre in PSII is hypothesised to have evolved froma homodimeric ancestor, which was capable of charge separation on both sides of the reaction centre. Ancestral Sequence Reconstruction (ASR) has been performed to predict the protein sequences of the homodimeric and heterodimeric ancestors in PSII, named AncD0 and AncD1. Analysis of AncD0 sequences was used to rationalise charge separation, quinone chemistry, and electron donation within the homodimeric reaction centre. Additionally, AncD1 sequences were shown to support water oxidation, suggesting that the rogue and super-rogue D1 isoforms have lost their water oxidation capability. Site directed mutagenesis of the D2 subunit in PSII was used to reconstruct ancestral traits and explain the origin of the functional asymmetry in the homodimeric RC. In a knockout of the redox-active Tyrosine D, D2-Y160F, the S1 state of the Mn4CaO5 cluster was observed to decay to the S0 state during long dark adaptations, in thylakoids membranes lacking the extrinsic PSII subunits. This was not observed in intact D2-Y160F thylakoids, providing a rational for the oxidation of S0 to S1 by Tyrosine D, and its strict conservation in all known D2 proteins. EPR and time-resolved fluorescence measurements were used to show that the D2-R294N mutation inhibits the formation of the stable Tyrosine D radical. It is proposed that D2-R294 evolved to fulfil two roles: firstly, as a controller of the hydrogen-bonding direction around Tyrosine D, and secondly, as a fine-tuner of the PD1 and PD2 redox potentials so that the cation is localised on the D1 side of the RC. Finally, sequence analysis and transient absorption spectroscopy was used to investigate the function of the atypical D1 isoform, rogue D1 (rD1). The results of these analyses were combined to propose a role for rD1-PSII as a light-activated signalling complex, used by nitrogen-fixing cyanobacteria to indicate that nitrogen fixation should be switched off.
Ein Kannelurenstein von Moide bei Soltau, Ldkr. Soltau-Fallingbostel
Creators: name: Raddatz, Klaus
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2018

description: -
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 60 (1991): Nachrichten aus Niedersachsens Urgeschichte
Supplementary document for Modeling of ring-core trench-assisted few-mode BDFA for 7-mode signal gain equalization - 6123854.pdf
Creators: name: Wang, Dingchen
name: Pei, Li
name: Zheng, Jingjing
name: wang, Jianshuai
name: Xu, Wenxuan
name: Li, Jing
name: NIng, Tigang
Publisher: name: Optica Publishing Group
Year: 2022
Subjects: Uncategorized

description: Verify the applicability of three-level simulation to BDFA through experiments
An equality between entanglement and uncertainty
Creators: name: Berta, Mario
name: Coles, Patrick J.
name: Wehner, Stephanie
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Heisenberg's uncertainty principle implies that if one party (Alice) prepares a system and randomly measures one of two incompatible observables, then another party (Bob) cannot perfectly predict the measurement outcomes. This implication assumes that Bob does not possess an additional system that is entangled to the measured one; indeed the seminal paper of Einstein, Podolsky and Rosen (EPR) showed that maximal entanglement allows Bob to perfectly win this guessing game. Although not in contradiction, the observations made by EPR and Heisenberg illustrate two extreme cases of the interplay between entanglement and uncertainty. On the one hand, no entanglement means that Bob's predictions must display some uncertainty. Yet on the other hand, maximal entanglement means that there is no more uncertainty at all. Here we follow an operational approach and give an exact relation - an equality - between the amount of uncertainty as measured by the guessing probability, and the amount of entanglement as measured by the recoverable entanglement fidelity. From this equality we deduce a simple criterion for witnessing bipartite entanglement and a novel entanglement monogamy equality.
description: v2: published as "Entanglement-assisted guessing of complementary measurement outcomes", 11 pages, 1 figure
Adaptive estimation and change detection of correlation and quantiles for evolving data streams
Creators: name: Noble, Jordan
Publisher: name: Imperial College London
Year: 2022

description: Streaming data processing is increasingly playing a central role in enterprise data architectures due to an abundance of available measurement data from a wide variety of sources and advances in data capture and infrastructure technology. Data streams arrive, with high frequency, as never-ending sequences of events, where the underlying data generating process always has the potential to evolve. Business operations often demand real-time processing of data streams for keeping models up-to-date and timely decision-making. For example in cybersecurity contexts, analysing streams of network data can aid the detection of potentially malicious behaviour. Many tools for statistical inference cannot meet the challenging demands of streaming data, where the computational cost of updates to models must be constant to ensure continuous processing as data scales. Moreover, these tools are often not capable of adapting to changes, or drift, in the data. Thus, new tools for modelling data streams with efficient data processing and model updating capabilities, referred to as streaming analytics, are required. Regular intervention for control parameter configuration is prohibitive to the truly continuous processing constraints of streaming data. There is a notable absence of such tools designed with both temporal-adaptivity to accommodate drift and the autonomy to not rely on control parameter tuning. Streaming analytics with these properties can be developed using an Adaptive Forgetting (AF) framework, with roots in adaptive filtering. The fundamental contributions of this thesis are to extend the streaming toolkit by using the AF framework to develop autonomous and temporally-adaptive streaming analytics. The first contribution uses the AF framework to demonstrate the development of a model, and validation procedure, for estimating time-varying parameters of bivariate data streams from cyber-physical systems. This is accompanied by a novel continuous monitoring change detection system that compares adaptive and non-adaptive estimates. The second contribution is the development of a streaming analytic for the correlation coefficient and an associated change detector to monitor changes to correlation structures across streams. This is demonstrated on cybersecurity network data. The third contribution is a procedure for estimating time-varying binomial data with thorough exploration of the nuanced behaviour of this estimator. The final contribution is a framework to enhance extant streaming quantile estimators with autonomous, temporally-adaptive properties. In addition, a novel streaming quantile procedure is developed and demonstrated, in an extensive simulation study, to show appealing performance.
Inequality between size and angular momentum for bodies
Creators: name: Dain, Sergio
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: A universal inequality that bounds the angular momentum of a body by the square of its size is presented and heuristic physical arguments are given to support it. We prove a version of this inequality, as consequence of Einstein equations, for the case of rotating axially symmetric, constant density, bodies. Finally, the physical relevance of this result is discussed.
description: Improvements in the heuristic arguments. 5 pages
Michael Geschwinde, Höhlen im Ith. Urgeschichtliche Opferstätten im südniedersächsischen Bergland
Creators: name: Polenz, Hartmut
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2018

description: Rezension zu: Michael Geschwinde, Höhlen im Ith. Urgeschichtliche Opferstätten im südniedersächsischen Bergland. Mit einem Beitrag von Michael Schultz. — Veröffentlichungen der urgeschichtlichen Sammlungen des Landesmuseums zu Hannover, Band 33. Verlag August Lax, Hildesheim 1988. 176 Seiten mit 82 Abbildungen sowie 2 Faksimilies, 1 Karte und 19 Tafeln. ISBN 3-7848-1233-3.
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 60 (1991): Nachrichten aus Niedersachsens Urgeschichte
Alfons Zettler, Die frühen Klosterbauten der Reichenau. Ausgrabungen — Schriftquellen — St. Galler Klosterplan
Creators: name: Stephan, Hans-Georg
Publisher: name: Nachrichten aus Niedersachsens Urgeschichte
Year: 2018

description: Rezension zu: Alfons Zettler, Die frühen Klosterbauten der Reichenau. Ausgrabungen — Schriftquellen — St. Galler Klosterplan. Mit einem Beitrag von Helmut Schlichtherle. — Archäologie und Geschichte. Freiburger Forschungen zum ersten Jahrtausend in Südwestdeutschland, Band 3. Herausgegeben von Hans Ulrich Nuber, Karl Schmid und Heiko Steuer. Jan Thorbecke Verlag, Sigmaringen 1988. 396 Seiten, 98 Abbildungen, darunter 1 farbige. Leinen mit farbigem Schutzumschlag. ISBN 3-79995-7353-4.
description: Nachrichten aus Niedersachsens Urgeschichte, Bd. 60 (1991): Nachrichten aus Niedersachsens Urgeschichte
Additional file 2 of Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle
Creators: name: Prowse-Wilkins, Claire P.
name: Lopdell, Thomas J.
name: Xiang, Ruidong
name: Vander Jagt, Christy J.
name: Littlejohn, Mathew D.
name: Chamberlain, Amanda J.
name: Goddard, Michael E.
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: Supplementary Table 2. The number of genes or exons with a heterozygous SNP (tSNP), the number of genes or exons with multiple tSNP and the number of genes or exons where the tSNP phenotypes within were significantly different (p<0.05). Supplementary Table 3. For each histone modification, the number of peaks with a heterozygous SNP (pSNP), the number of peaks with multiple pSNP and the number of peaks where the pSNP phenotypes within were significantly different (p<0.05).
The One-Third-Trick and Shift Operators
Creators: name: Lechner, Richard
Publisher: name: arXiv
Year: 2012
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics

description: In this paper we obtain a representation as martingale transform operators for the rearrangement and shift operators introduced by T. Figiel. The martingale transforms and the underlying sigma algebras are obtained explicitly by combinatorial means. The known norm estimates for those operators are a direct consequence of our representation.
Examining the Link Between Dental Development, BMI and Diet
Creators: name: Cardona Salazar, Diana Katerine
Publisher: name: University of Illinois at Chicago
Year: 2021
Subjects: Uncategorized

description: Hypothesis and Objective: We aim to explore whether macronutrient intake is positively correlated with timing of dental development and, if so, whether this relationship holds true regardless of BMI. Methods: Panoramic radiographs of 9-15.9 YO children (n= 112, 59 males) were used to estimate dental age based on maturity scores of permanent mandibular teeth. BMI values and nutritional data from a validated nutritional questionnaire were recorded. Results: Obese and overweight children showed accelerated dental development relative to normal weight children (1.1 years and 0.6 years respectively; p=0.003), with obese subjects showing the greatest advancement (p=0.001). In terms of nutrition, we found a weak association between dental development and total caloric intake when controlling for age (rho = 0.197; p=0.036). Conclusions: In the current sample, we confirm prior work which has suggested that high BMI children have accelerated dental development. In terms of the relationship between dental development and diet, we see no evidence that a particular macronutrient consumption influences timing of dental development. Our results suggest a weak, positive correlation between total calories consumed and dental development. This is in agreement with prior research by Jääsaari and colleagues (2016) which found that advanced dental maturity was associated with increased energy intake.
Impact of a multi-patient simulation event on physical therapy student confidence: a quasi-experimental study
Creators: name: Ross, Sarah
name: Washmuth, Nicholas
Publisher: name: The Journal of Clinical Education in Physical Therapy
Year: 2020

description: Purpose: Simulation is a long-established learning and assessment activity in healthcare education. Simulation has been used to provide opportunities for students to experience complex patient interactions in a low-risk setting to prepare students to manage all the demands of total patient care as new practitioners. The purpose of this quasi-experimental, single cohort study, with pre–post quantitative survey analysis including theme frequency, was to determine how participating in a multi-patient simulation consisting of different clinical settings and diagnoses would impact physical therapy students’ confidence in clinical and decision-making skills. Methods: Thirty-three, entry-level Doctor of Physical Therapy students completed a simulation and debriefing across four different healthcare settings while addressing different aspects of patient management within each of these settings. Students completed two surveys before and after this simulation to measure their self-appraised confidence. Quantitative data from these surveys were analyzed using Wilcoxon tests and the free-response entries from the surveys were analyzed for theme occurrence frequency. Results: Students’ total clinical skill confidence scores decreased (P = 0.015), specifically in areas of strength testing (P = 0.008), postural assessment (P = 0.002), and planning an appropriate intervention plan (P = 0.033). Students’ total decision-making confidence scores did not significantly change; however, areas of improvement included recognizing physiological and psychological changes in patients in a timely manner (P = 0.025) and distinguishing between clinically important and lower priority impairments (P = 0.048). Occurrence of theme frequencies from free responses revealed a decrease in student confidence related to “flow and organization” as well as “evaluation.” Conclusion: While incorporating a multi-patient simulation improved some aspects of students’ self-appraised confidence in clinical decision-making skills, there was an unexpected decrease in students’ overall confidence.
description: The Journal of Clinical Education in Physical Therapy, Vol 2 (2020)
title: Voices “Herd”
title: A Social and Sentiment Analysis of Consumers Perceptions of Fair Oaks Farms
titleType: Subtitle
Creators: name: Nesmith, Jacelyn
Publisher: name: University of Kentucky Libraries
Year: 2020

description: Americans are searching for more information than just cost and quality of their food. Today, consumers are searching for information regarding the production practices and how animals are treated during the process. As consumers do not always have a first-hand source for this information, they are often referring to social media to have their questions answered. Social media has the reputation to negatively influence public perceptions of the agricultural industry. An example of an organization experiencing the consequences of social media influencing public opinion is Fair Oaks Farms. In 2019, an undercover animal rights activist group made accusations of poor animal welfare at Fair Oaks Farms. The purpose of this study is to determine how online media impacted Twitter users’ opinion of Fair Oaks Farms and the welfare of their animals during the video mission of ARM Investigators. Utilizing a convergent mixed methods approach, the researcher conducted a social and sentiment analysis to uncover the impact and attitudes towards Fair Oaks Farms upon the release of these videos. Social Studio, a social listening tool, allowed the researcher to collect tweets directly related to this phenomenon for the analysis. This study determined the videos about Fair Oaks Farms had a negative influence on Twitter users’ perceptions of the farm and the industry. Additionally, this study suggested the impact the media has on public opinion and disseminating information online.
description: Copyright © Jacelyn De’Nae Nesmith 2020
Higher mortality associated with the SARS-CoV-2 Delta variant in the Western Cape, South Africa, using RdRp target delay as a proxy: a cross-sectional study.
Creators: name: Hussey, Hannah
name: Davies, Mary-Ann
name: Heekes, Alexa
name: Williamson, Carolyn
name: Valley-Omar, Ziyaad
name: Hardie, Diana
name: Korsman, Stephen
name: Doolabh, Deelan
name: Preiser, Wofgang
name: Maponga, Tongai
name: Iranzadeh, Arash
name: Engelbrecht, Susan
name: Wasserman, Sean
name: Schrueder, Neshaad
name: Boloko, Linda
name: Symons, Greg
name: Raubenheimer, Peter
name: Viljoen, Abraham
name: Parker, Arifa
name: Cohen, Cheryl
name: Jasat, Waasila
name: Lessells, Richard
name: Wilkinson, Robert J
name: Boulle, Andrew
name: Hsiao, Marvin
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: classificationCode: Infectious Disease
subject: Infectious Disease
classificationCode: Immunology
subject: Immunology
subject: FOS: Clinical medicine
classificationCode: Human Biology & Physiology
subject: Human Biology & Physiology
classificationCode: Model organisms
subject: Model organisms

description: Background:
The SARS-CoV-2 Delta variant (B.1.617.2) has been associated with more severe disease, particularly when compared to the Alpha variant. Most of this data, however, is from high income countries and less is understood about the variant's disease severity in other settings, particularly in an African context, and when compared to the Beta variant. Methods:
A novel proxy marker, RNA-dependent RNA polymerase (RdRp) target delay in the Seegene Allplex TM 2019-nCoV (polymerase chain reaction) PCR assay, was used to identify suspected Delta variant infection in routine laboratory data. All cases diagnosed on this assay in the public sector in the Western Cape, South Africa, from 1 April to 31 July 2021, were included in the dataset provided by the Western Cape Provincial Health Data Centre (PHDC). The PHDC collates information on all COVID-19 related laboratory tests, hospital admissions and deaths for the province. Odds ratios for the association between the proxy marker and death were calculated, adjusted for prior diagnosed infection and vaccination status.
Results:
A total of 11,355 cases with 700 deaths were included in this study. RdRp target delay (suspected Delta variant) was associated with higher mortality (adjusted odds ratio [aOR] 1.45; 95% confidence interval [CI]: 1.13-1.86), compared to presumptive Beta infection. Prior diagnosed infection during the previous COVID-19 wave, which was driven by the Beta variant, was protective (aOR 0.32; 95%CI: 0.11-0.92) as was vaccination (aOR [95%CI] 0.15 [0.03-0.62] for complete vaccination [≥28 days post a single dose of Ad26.COV2.S or ≥14 days post second BNT162b2 dose]).
Conclusion:
RdRp target delay, a proxy for infection with the Delta variant, is associated with an increased risk of mortality amongst those who were tested for COVID-19 in our setting.
title: Emotional Closeness within Romantic Relationships
title: Is There Transmission Between Generations?
titleType: Subtitle
Creators: name: Fey, McKenna
Publisher: name: University of Kentucky Libraries
Year: 2020

description: This study tested the existence of intergenerational transmission of romantic emotional closeness using Galovan and Schramm’s (2018) model of relationship flourishing as a theoretical backbone. Romantic emotional closeness in the present study included intimacy (i.e., self-disclosure), admiration (i.e., appreciation expression), and dyadic coping. Couples among three generations from the Panel of Analysis of Intimate Relationships and Family Dynamics (Brüderl et al., 2013) were examined to test whether romantic emotional closeness in the first generation predicted romantic emotional closeness in the second generation, and whether that of the second generation predicted that of the third. Regressions within a partial latent model showed that intergenerational transmission existed between the first and second generation but not between the second and third generation. One possible explanation for this finding is a small sample size within the third generation, which limited the data used. Implications for future research, clinicians, and theorists are discussed.
description: Copyright © McKenna Diane Fey 2020
Frequency and function of lymphocytes in labouring compared to non-labouring decidua
Creators: name: Whettlock, Emily
Publisher: name: Imperial College London
Year: 2023

description: The uterine mucosa, known as the decidua during pregnancy, contains a unique immune microenvironment. Decidual immune activation has been hypothesised to initiate labour, the end of pregnancy when the muscles contract to excel the baby. Understanding this process could facilitate the development of medications to delay labour and prevent preterm birth. Prior research examining decidual immune cells during labour lacked known decidual markers. Single cell RNA sequencing (scRNAseq) data has provided more information about the uterine immune landscape e.g. identifying three uterine NK subsets (uNK1-3). Using existing scRNAseq data and novel flow cytometry data, I examined decidual immune cells during labour. I integrated existing uterine scRNAseq datasets, from throughout the reproductive cycle. The data showed the immune environment is dynamic, suggesting roles for particular cells at different stages e.g. uNKs in the first trimester. uNK1 were thought to aid placental implantation, due to their receptor expression profile. However, I noted an upregulation of these receptors in all uNK subsets in the first trimester, suggesting they are all involved. I optimised a protocol to isolate immune cells from term decidua. The scRNAseq and flow cytometry data suggests that uNKs and Tregs do not have a significant role initiating labour. My examination of an existing scRNAseq dataset found a cluster of chemokine producing myeloid cells which expanded in the decidua parietalis during labour. This, along with insights from rat models, suggests these myeloid cells are potential initiators of labour. The integrated analysis of uterine immune cells could be used as a guide for investigating abnormalities throughout the reproductive cycle. For the labouring data, uNK and Tregs have been excluded as having a large role in initiating term labour and myeloid cells put forward as potential candidates for this role. Also, this term data could guide future studies on preterm birth.
Additional file 3 of Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle
Creators: name: Prowse-Wilkins, Claire P.
name: Lopdell, Thomas J.
name: Xiang, Ruidong
name: Vander Jagt, Christy J.
name: Littlejohn, Mathew D.
name: Chamberlain, Amanda J.
name: Goddard, Michael E.
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: Supplementary Table 4. The number of peak-exon pairs with shared allele-specific QTL variants as well as the distance between peak-exon pairs and the average number of times a peak was associated with an exon and vice versa. Supplementary Table 5. The number of peak-exon pairs with shared traditional QTL as well as the distance between peak-exon pairs and the average number of times a peak was associated with an exon and vice versa.