cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
From the canvas to the web : the expansion of video installation through space.
Creators: name: Galimberti, Elena
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This thesis proposes a novel interpretative key for the study of video installations based on the recognition that these artworks are products of a spatial practice. Through this interpretation, I revisit the history of video installations starting from the seminal work of Lucio Fontana, who, in the 1950s, advocated the expansion of art beyond the limits of the canvas and of matter itself. Video art in turn heralded the production of artworks freed from physical matter, in a free-floating video signal. This was occurring at the same time as Minimalist artists stimulated forms of active spectatorship through the confronting blankness of the often industrially produced art object, leading to what has become known as installation art, which elicits spatial narratives through complex three-dimensional arrangements. Video installation represents in many ways a synthesis of these practices that enables artists to generate immersive environments. On the basis of this history, I argue that the development of video installation has involved its expansion through space. While video installation initially transcended the boundaries of the television set by colonising the exhibition space and the space between screens, a more recent expansion entails the use of large screens in public spaces and projections against architectural elements in the city. The future of this evolution is starting to take shape with the emergence of locative art and the exploration of the interplay between space and place-based technologies. However, if Fontana's vision of art freed from matter is becoming a reality, the 'immaterial' nature of video and the irreproducibility of site-specific video installations produce a problem for the conservation of these artworks. Such conservation issues are compounded by the perishability of supports and the fast rate of obsolescence of video formats. Acknowledging the risk of cultural amnesia associated with the rise of a culture, of immediacy, this thesis considers the currently burgeoning platform for the archiving of this art form: The quasi-utopian space of the Web.
title: Investigations of muscles with different fibre distribution by using 31P-MRS
Creators: name: Burmeister, Hartmut
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: Beyond an appropriate training many sport disciplines require a congenital optimal fiber distribution in special musclesto become ahigh performance athlete. However, it was observed that conversions between different fiber types can also beinduced...
title: Watch your step: Painful conditions of the plantar region of the foot
Creators: name: Miranda, Frederico
Publisher: name: European Congress of Radiology
Year: 2009

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: • Review the anatomy of the plantar compartment of the foot. • Describe the imaging findings of painful conditions arising from or extending into the plantar region of the...
Sonnenfleckenzeichnung Nr. 222.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.09.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Cyrtalabulus yemenensis Gusenleitner 2007
Creators: name: Carpenter, James M.
name: Gadallah, Neveen S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Vespidae
Cyrtalabulus
Cyrtalabulus yemenensis

description: Cyrtalabulus yemenensis Gusenleitner, 2007
Distribution in the Arabian Peninsula: Yemen (Gusenleitner 2007, 2013).
Extralimital distribution: No records.
description: Published as part of Carpenter, James M. & Gadallah, Neveen S., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Vespidae, pp. 191-216 in Zootaxa 4754 (1) on page 196, DOI: 10.11646/zootaxa.4754.1.20, http://zenodo.org/record/3719047
Sonnenfleckenzeichnung Nr. 164.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.07.1962, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
title: Soft tissue solitary fibrous tumour: A pictorial review
Creators: name: Simon-Olivé, Cristina
Publisher: name: European Congress of Radiology
Year: 2009

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: 1. To illustrate the imaging characteristics of soft tissue solitary fibrous tumour (SFT). 2. To correlate these findings with pathological...
Collective difference: re-presentation as feminist practice
Creators: name: Roe, Alex Martinis
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This PhD research explores the question: what can be a founding premise now for art practice as feminist action? Judith Butler’s theory of gender performativity problematises the identity politics of who can constitute the feminist subject. However, Luce Irigaray’s textual practice will inform an argument for the importance of not only a feminist, but also a feminine genealogy. Butler’s gender performativity and Irigaray’s mimesis have informed the PhD research in its attempt to simultaneously deconstruct the feminine and to affirm the potential to contribute to a feminist genealogy. In the first stage of the research, 1:1 scale self-portrait video installations performatively altered the viewer’s mode of consumption of representational images of the artist. An analysis of the contextual contingency of the artist’s authorship informed strategies which attempted to shift normative modes of spectatorship. The second major body of work involved a series of re-enactment and citational works that explore the development of a specifically feminist genealogy; mimetic language as feminine and the contemporary relationship between documentation and live works. The final stage of the research relocated the object of the work to the event of the art encounter. This relocation involved an emphasis on the co-dependency of meaning and the performative effect of an artist’s reception and their interlocutors. This co-dependency allows for the development of a feminine genealogy, which does not rely on representations of women, but on the latent subtext of representational conventions. That is, what Irigaray calls specular figurations of the feminine: the trace of that which legitimates language via its exclusion from signification.
Sonnenfleckenzeichnung Nr. 166.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.07.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Profiling The Unemployed
Creators: name: Niklas, Jędrzej
Publisher: name: Zenodo
Year: 2018
Subjects: Algorithmic decision-making
Algorithms
Artificial Intelligence
Unemployed
Transparency
Public Administration
Profiling

description: Since 2014, job centres in Poland have been using an algorithmic decision-making system to categorize unemployed people and allocated different types of assistance. In the context of the global financial crisis in 2007, job centres have tried to become more efficient, among other things by introducing more individual advice by profiling the unemployed using an algorithm. However, this new tool created many challenges for a transparent decision-making and effective use of social rights. In this article, five lessons learned from profiling the unemployed are presented as a case of automated decisions in public administration.
Machine learning and classical MD simulation to identify inhibitors against the P37 envelope protein of monkeypox virus
Creators: name: Rout, Madhusmita
name: Dey, Suchanda
name: Mishra, Sarbani
name: Panda, Sunita
name: Singh, Mahender Kumar
name: Sinha, Rohan
name: Dehury, Budheswar
name: Pati, Sanghamitra
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Monkeypox virus (MPXV) outbreak is a serious public health concern that requires international attention. P37 of MPXV plays a pivotal role in DNA replication and acts as one of the promising targets for antiviral drug design. In this study, we intent to screen potential analogs of existing FDA approved drugs of MPXV against P37 using state-of-the-art machine learning and computational biophysical techniques. AlphaFold2 guided all-atoms molecular dynamics simulations optimized P37 structure is used for molecular docking and binding free energy calculations. Similar to members of Phospholipase-D family , the predicted P37 structure also adopts a β-α-β-α-β sandwich fold, harbouring strongly conserved HxKxxxxD motif. The binding pocket comprises of Tyr48, Lys86, His115, Lys117, Ser130, Asn132, Trp280, Asn240, His325, Lys327 and Tyr346 forming strong hydrogen bonds and dense hydrophobic contacts with the screened analogs and is surrounded by positively charged patches. Loops connecting the two domains and C-terminal region exhibit high degree of flexibility. In some structural ensembles, the partial disorderness in the C-terminal region is presumed to be due to its low confidence score, acquired during structure prediction. Transition from loop to β-strands (244–254 aa) in P37-Cidofovir and its analog complexes advocates the need for further investigations. MD simulations support the accuracy of the molecular docking results, indicating the potential of analogs as potent binders of P37. Taken together, our results provide preferable understanding of molecular recognition and dynamics of ligand-bound states of P37, offering opportunities for development of new antivirals against MPXV. However, the need of in vitro and in vivo assays for confirmation of these results still persists. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 187.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 01.08.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Delta anomalum
Creators: name: Carpenter, James M.
name: Gadallah, Neveen S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Vespidae
Delta
Delta anomalum

description: Delta anomalum (Zavattari, 1909)
Distribution in the Arabian Peninsula:? Saudi Arabia (Giordani Soika 1934; Zalat et al. 1992 as Alfieria anomala). Extralimital distribution: Egypt, Iran.
description: Published as part of Carpenter, James M. & Gadallah, Neveen S., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Vespidae, pp. 191-216 in Zootaxa 4754 (1) on page 196, DOI: 10.11646/zootaxa.4754.1.20, http://zenodo.org/record/3719047
Sonnenfleckenzeichnung Nr. 235.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.09.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Sonnenfleckenzeichnung Nr. 257.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.10.1962, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Identification of levomenthol derivatives as potential dipeptidyl peptidase-4 inhibitors: a comparative study with gliptins
Creators: name: Alade, Adebowale A.
name: Ahmed, Samad A.
name: Mujwar, Somdutt
name: Kikiowo, Babatomiwa
name: Akinnusi, Precious A.
name: Olubode, Samuel O.
name: Olufemi, Oluwafeyisayomi M.
name: Ohilebo, Abass A.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biophysics
Biochemistry
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Dipeptidyl peptidase-4 (DPP4) inhibitors are a potent therapeutic treatment for type 2 diabetes mellitus (T2DM). There is a family of compounds used as DPP4 inhibitors (DPP4Is) called gliptins. They bind tightly to DPP4 to form an inactive protein–ligand complex. However, there remains a need to identify novel DPP4Is that are more efficacious and safer due to the increasing prevalence of T2DM and the undesirable side effects of gliptins. To identify potential DPP4Is, we screened over 1800 novel compounds in a comparative study with gliptins. We performed dual-factor molecular docking to assess the binding affinity of the compounds to DPP4 and found four compounds with a higher binding affinity to DPP4 than currently used gliptins. The newly identified compounds interacted with the dyad glutamate (GLU205 and GLU206) and tyrosine (TYR662 and TYR666) residues in DPP4’s active site. We performed molecular dynamics simulations to determine the stability of the protein-ligand complexes formed by the compounds and DPP4. Furthermore, we examined the toxicity and pharmacological profile of the compounds. The compounds are drug-like, easy to synthesize, and relatively less toxic than gliptins. Collectively, our results suggest that the novel compounds are potential DPP4Is and should be considered for further studies to develop novel antidiabetics. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 201.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 15.08.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Delta asina subsp. mixtum
Creators: name: Carpenter, James M.
name: Gadallah, Neveen S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Vespidae
Delta
Delta asina
Delta asina ssp. mixtum (giordani soika, 1944)

description: Delta asina ssp. mixtum (Giordani Soika, 1944)
Distribution in the Arabian Peninsula: Arabia (Zalat et al. 1993), Oman (Giordani Soika 1957 as Eumenes mixtus; Guichard 1986; Gusenleitner 2013), Saudi Arabia (Giordani Soika 1970; Guichard 1986; Gusenleitner 2013).
Extralimital distribution: Chad, Egypt, Eritrea, Ethiopia, Israel, Jordan, Niger, Palestine, Somalia, Sudan.
description: Published as part of Carpenter, James M. & Gadallah, Neveen S., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Vespidae, pp. 191-216 in Zootaxa 4754 (1) on page 196, DOI: 10.11646/zootaxa.4754.1.20, http://zenodo.org/record/3719047
MAO inhibiting phytochemicals from the roots of Glycyrrhiza glabra L.
Creators: name: Bhattacharjee, Monojit
name: Manoharan, Suryaa
name: Sathisaran, Umamaheswari
name: Tamatam, Anand
name: Perumal, Ekambaram
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Cancer

description: Glycyrrhizin, a natural compound that is substantially present in Glycyrrhiza glabra L. (Gg) root. Monoamine oxidase B (MAOB) inhibitor is used for the treatment of several important neuropsychological diseases like Parkinson’s disease. Gg is known to possess psychoactive properties which relates to its MAO inhibitory potential. This study sought to determine the MAO inhibition property of glycyrrhizin from Gg root extract. The Aqueous extract containing glycyrrhizin was isolated from the root of Gg and characterized using TLC, HPLC, and LC-MS techniques. In silico docking was conducted using Extra precision Glide 2018, Schrödinger docking suite. In addition, the pharmacokinetic properties of the compounds were predicted using SwissADME. The binding energies of the glycyrrhizin correlated well with their in vitro MAO inhibitory potential. Glycyrrhizin exhibited potent inhibitory activity towards MAOB whereas, an aqueous extract of Gg root inhibits both A and B forms of MAO enzyme. Further, molecular docking and molecular dynamics simulation showed that liquiritigenin and methoxyglabridin showed higher stability than other inhibitor compounds from the Gg root extract. These observations suggest that the phytochemicals from the Gg root extract have potent MAO inhibition properties, which can be exploited for the treatment of neurodegenerative disorders. Communicated by Ramaswamy H. Sarma Catecholamine content decrement in the brain may cause neurobehavioural disorders. MAO may degrade catecholamines in the brain. MAO inhibitors enhance the catecholamine levels. Glycyrrhiza glabra L. extract and their phytoconstituents exhibit MAO inhibiting properties. Glycyrrhizin can be used to treat Catecholamine mediated neurodegenerative disorders.
title: An autostereoscopic 3D display improves identification of intracranial arteries in 3D models from time-of-flight MR-angiography
Creators: name: Abildgaard, Andreas
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: An autostereoscopic 3D display (a display that provides 3D visualisation without the use of special glasses for viewing) has recently been developed as a prototype (1,2). . Pilot testing of this display has indicated improved visualisation of the...
An in-silico approach to unravel the structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHPS): a critical enzyme for sennoside biosynthesis in Cassia angustifolia Vahl
Creators: name: Thaker, Khushali
name: Patoliya, Jaimini
name: Rabadiya, Khushbu
name: Patel, Dhaval
name: Ponnuchamy, Manivel
name: Reddy, Nagaraja Reddy Rama
name: Joshi, Rushikesh
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: The laxative properties of senna are attributed to the presence of sennosides produced in the plant. The low production level of sennosides in the plant is an important impediment to their growing demand and utilization. Understanding biosynthetic pathways helps to engineer them in terms of enhanced production. The biosynthetic pathways of sennoside production in plants are not completely known yet. However, attempts to get information on genes and proteins engaged in it have been made which decode involvement of various pathways including shikimate pathway. 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHPS) is a key enzyme involved in sennosides production through the shikimate pathway. Unfortunately, there is no information available on proteomic characterization of DAHPS enzyme of senna (caDAHPS) resulting in lack of knowledge about its role. We for the first time characterized DAHPS enzyme of senna using in-silico analysis. To the best of our knowledge this is the first attempt to identify the coding sequence of caDAHPS by cloning and sequencing. We found Gln179, Arg175, Glu462, Glu302, Lys357 and His420 amino acids in the active site of caDAHPS through molecular docking. followed by molecular dynamic simulation. The amino acid residues, Lys182, Cys136, His460, Leu304, Gly333, Glu334, Pro183, Asp492 and Arg433 at the surface interact with PEP by van der Waals bonds imparting stability to the enzyme-substrate complex. Docking results were further validated by molecular dynamics. The presented in-silico analysis of caDAHPS will generate opportunities to engineer the sennoside biosynthesis in plants. Communicated by Ramaswamy H. Sarma
title: Percutaneous intervertebral disc decompression: Prospective study for pain evaluation
Creators: name: Filippiadis, Dimitrios
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: The long- term outcome, complications and occasionally suboptimal results which accompany open disc surgery in herniated discs [mri.jpg] have led to the development of other treatment techniques that avoid a surgical approach,through spinal canal,...
Delta dimidiatipenne
Creators: name: Carpenter, James M.
name: Gadallah, Neveen S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Vespidae
Delta
Delta dimidiatipenne

description: Delta dimidiatipenne (de Saussure, 1852)
Distribution in the Arabian Peninsula: Kuwait (Walker & Pittaway 1987; Al-Houty 1989, 1997), Oman (Walker & Pittaway 1987; Gusenleitner 2004, 2005, 2013; Castro & Dvořák 2009; Monks et al. 2019), Qatar (Guichard 1986), Saudi Arabia (de Saussure 1852 as Eumenes dimidiatipennis; Giordani Soika 1970; Guichard 1986; Walker & Pittaway 1987; Gadallah 2003; El-Hawagry et al. 2013 as Eumenes dimidiatipennis), United Arab Emirates (Roche 1981; Guichard 1986; Gillett & Howarth 2004; Gillett & Gillett 2005 as Delta diminuatipenne; Howarth & Gillett 2008; Gusenleitner 2010), Yemen (including Sokotra) (Kirby 1903 as E. dimidiatipennis; Kohl 1906 as E. dimidiatipennis; Giordani Soika 1974; Wahis 2000; Gusenleitner 2007; Castro & Dvořák 2009; Dvořák & Carpenter 2010; Gusenleitner 2013; Madl 2018).
Extralimital distribution: Afghanistan, Algeria, Canary Islands, Chad, Djibouti, Egypt, Eritrea, Ethiopia, India, Iran, Jordan, Mauritania, Morocco, Nepal, Niger, Pakistan, Somalia, South Africa, Sudan, Syria, Tajikistan, Turkmenistan, Turkey, Uganda.
description: Published as part of Carpenter, James M. & Gadallah, Neveen S., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Vespidae, pp. 191-216 in Zootaxa 4754 (1) on page 196, DOI: 10.11646/zootaxa.4754.1.20, http://zenodo.org/record/3719047
title: Retrieval of a new optional vena cava filter
Creators: name: Pieri, Stefano
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: •The role of vena cava filter has changed over the lastdecades.•Optional vena cava filters, removable after a long permanence, is the novely that overcomes the limits oftemporary and permanent filters.•We report our observations and problems...
Towards the social innovation lighthouse: European ecosystems addressing the innovation divide
Creators: name: SHINE 2Europe, Lda
name: i2CAT
name: Afedemy
name: Krakowski Park Technologiczny
Publisher: name: Zenodo
Year: 2024

description: The new European Innovation Agenda foresees as one of its flagships the aim of “Accelerating and strengthening innovation in European Innovation Ecosystemsacross the EU and addressing the innovation divide”. Two European Innovation Ecosystems funded Actions, SIRENE and INTEGER, are working towards this goal:SIRENE works to improve wellbeing and housing conditions by empowering social and private entrepreneurs, while INTEGER is focused on developing more robust,sustainable, and inclusive ecosystems for healthy living and wellbeing.

The document presents the main goals, objectives and aims.
title: Sonographically guided core needle biopsy of nonpalpable architectural distortions BI-RADS category 4A-B: Correlation with surgical excisional biopsy and follow-up
Creators: name: Baeva, Maria
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: To show the advantage of sonographically (US) guided core needle biopsy of nonpalpable architectural distortions (NPAD) BI-RADS category 4A-Bvisible on mammography for histological diagnosis and for patient management decision...
Sonnenfleckenzeichnung Nr. 232.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 16.09.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
title: MR-guided vacuum-assisted core-needle breast biopsy: Comparison of three vacuum-assisted biopsy devices
Creators: name: Scarth, Julia
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: Breast MRI is used in the work-up of women with a known diagnosis of breast cancer, and in screening of asymptomatic high-risk women. MRI-guided breast biopsy is increasingly required in the assessment of MRI detected lesions where a second look...
Sonnenfleckenzeichnung Nr. 215.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 29.08.1962, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Sonnenfleckenzeichnung Nr. 258.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.10.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
title: Gamekeeper
Creators: name: Bordet, Bertrand
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: Thumb metacarpophalangeal (MCP) joint strain is frequent. Gamekeeper's thumb, also called skier's thumb, accounts for 6% of skier traumas. During spraining with ligament tear, the adductor aponeurosis may become entrapped under the proximal ligament...
title: US-guided fine-needle aspiration cytology of 545 focal pancreatic lesions: Accuracy and short-term complications
Creators: name: Zamboni, Giulia
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: To assess accuracy and short-term complication rate of US-guided fine needle aspiration cytology (FNAc) of focal pancreatic...
title: Magnetic resonance imaging (MR) with sensitization maneuvers for thoracic outlet syndrome (TOS)
Creators: name: Yang, Je
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: Thoracic outlet syndrome (TOS) is defined clinically as the compression of neurovascular bundle in a confined space defined as thoracic outlet. The thoracic outlet extends from the cervical spine to the lower border of the pectoralis minor muscle,...
title: Foreign bodies: Their appearance on X-ray, ultrasound, CT and MRI
Creators: name: Kraus, Alexandra
Publisher: name: European Congress of Radiology
Year: 2009

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: The learning objective of this presentation is to demonstrate the appearance of different types of foreign bodies in different imaging modalities and therefore to help choosing the right imagingmodality for the detection of foreign bodies of various...
title: Preoperative chemo-radiation therapy in mixoid liposarcoma of the extremities: Correlation between morphologic and perfusional MR patterns and pathological patterns to predict pathologic tumor response
Creators: name: Messina, Antonella
Publisher: name: European Congress of Radiology
Year: 2009

description: Purpose Methods and Materials Results Conclusion
description: Purpose: Myxoid liposarcoma is the second most common type of liposarcoma and represents 20%–50% of all liposarcomas. Myxoid liposarcomas account for 10% of all soft-tissue sarcomas. Extremity myxoidliposarcomas are most frequently intermuscular lesions...
Getting on board: designing the user experience of bicycles on Melbourne’s future metro trains
Creators: name: FU, LISA QI
Publisher: name: Monash University
Year: 2021
Subjects: Industrial and product design
Design not elsewhere classified

description: This thesis investigates, through design, improving the experience of passengers bringing their bicycles on board metropolitan trains in Melbourne. Design practice was used to apply the research findings to a local Melbourne context by designing a dedicated bicycle zone for metropolitan trains in Melbourne. The design research project has resulted in an expanded understanding of passengers travelling with bicycles, as well as a number of design outcomes. The outcomes from this work have important implications for rail operators, designers and planners, positioning rail in a sustainable future and encouraging more bicycle use by improving the experience for bicycles on board.
Delta emarginatum
Creators: name: Carpenter, James M.
name: Gadallah, Neveen S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Vespidae
Delta
Delta emarginatum

description: Delta emarginatum (Linnaeus, 1758)
Distribution in the Arabian Peninsula: Saudi Arabia (Giordani Soika 1957 as Eumenes maxillosus savignyi Guérin- Méneville, 1835; Guichard 1986; Gadallah 2003), Yemen (Giordani Soika 1957 as E. m. savignyi; Gusenleitner 2007).
Extralimital distribution: Algeria, Angola, Botswana, Burkina Faso, Burundi, Cameroon, Cape Verde Islands, Central African Republic, Comoros, Congo, Egypt, Equatorial Guinea, Eritrea, Ethiopia, Gabon, Gambia, Ivory Coast, Kenya, Liberia, Libya, Malawi, Mali, Madagascar, Mauritania, Monzambique, Namibia, Niger, Nigeria, Rwanda, Senegal, Seychelles, Sierra Leone, Somalia, South Africa, Sudan, Tanzania, Togo, Zambia.
description: Published as part of Carpenter, James M. & Gadallah, Neveen S., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Vespidae, pp. 191-216 in Zootaxa 4754 (1) on page 196, DOI: 10.11646/zootaxa.4754.1.20, http://zenodo.org/record/3719047
Computational and experimental validation of phthalocyanine and hypericin as effective SARS-CoV-2 fusion inhibitors
Creators: name: Romeo, Alice
name: Cappelli, Giulia
name: Iacovelli, Federico
name: Colizzi, Vittorio
name: Falconi, Mattia
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Phthalocyanine and hypericin have been previously identified as possible SARS-CoV-2 Spike glycoprotein fusion inhibitors through a virtual screening procedure. In this paper, atomistic simulations of metal-free phthalocyanines and atomistic and coarse-grained simulations of hypericins, placed around a complete model of the Spike embedded in a viral membrane, allowed to further explore their multi-target inhibitory potential, uncovering their binding to key protein functional regions and their propensity to insert in the membrane. Following computational results, pre-treatment of a pseudovirus expressing the SARS-CoV-2 Spike protein with low compounds concentrations resulted in a strong inhibition of its entry into cells, suggesting the activity of these molecules should involve the direct targeting of the viral envelope surface. The combination of computational and in vitro results hence supports the role of hypericin and phthalocyanine as promising SARS-CoV-2 entry inhibitors, further endorsed by literature reporting the efficacy of these compounds in inhibiting SARS-CoV-2 activity and in treating hospitalized COVID-19 patients. Communicated by Ramaswamy H. Sarma
Sonnenfleckenzeichnung Nr. 271.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 30.10.1962, erstellt von Araldo Pittini, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
Computational analysis of sodium-dependent phosphate transporter SLC20A1/PiT1 gene identifies missense variations C573F, and T58A as high-risk deleterious SNPs
Creators: name: Sankari, G. Siva
name: James, Remya
name: Payva, Febby
name: Sivaramakrishnan, Venketesh
name: Kumar, T. V. Vineeth
name: Kanchi, Subbarao
name: Santhy, K. S.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mental Health
subject: Hematology

description: SLC20A1/PiT1 is a sodium-dependent inorganic phosphate transporter, initially recognized as the retroviral receptor for Gibbon Ape Leukemia Virus in humans. SNPs in SLC20A1 is associated with Combined Pituitary Hormone Deficiency and Sodium Lithium Counter transport. Using in silico techniques, we have screened the nsSNPs for their deleterious effect on the structure and function of SLC20A1. Screening with sequence and structure-based tools on 430 nsSNPs, filtered 17 nsSNPs which are deleterious. To evaluate the role of these SNPs, protein modeling and MD simulations were performed. A comparative analysis of model generated with SWISS-MODEL and AlphaFold shows that many residues are in the disallowed region of Ramachandran plot. Since SWISS-MODEL structure has a 25-residue deletion, the AlphaFold structure was used to perform MD simulation for equilibration and structure refinement. Further, to understand perturbation of energetics, we performed in silico mutagenesis and ΔΔG calculation using FoldX on MD refined structures, which yielded SNPs that are neutral (3), destabilizing (12) and stabilizing (2) on protein structure. Furthermore, to elucidate the impact of SNPs on structure, we performed MD simulations to discern the changes in RMSD, Rg, RMSF and LigPlot of interacting residues. RMSF profiles of representative SNPs revealed that A114V (neutral) and T58A (positive) were more flexible & C573F (negative) was more rigid compared to wild type, which is also reflected in the changes in number of local interacting residues in LigPlot and ΔΔG. Taken together, our results show that SNPs can lead to structural perturbations and impact the function of SLC20A1 with potential implications for disease. Communicated by Ramaswamy H. Sarma
title: Leprosy (Hansen’s disease): Why it is important to remember “forgotten diseases” in Europe
Creators: name: Sanchez-Montanez, Angel
Publisher: name: European Congress of Radiology
Year: 2009

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References
description: Learning objectives: Until recently, European radiologists faced a limited, well-defined range of possible diagnoses in our daily practice. However, immigration and travel have changed this scenario: diseases that were endemic to other continents are becoming more...
Sonnenfleckenzeichnung Nr. 192.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.08.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek
A new horizon in the phosphorylated sites of AGA: the structural impact of C163S mutation in aspartylglucosaminuria through molecular dynamics simulation
Creators: name: Balasundaram, Ambritha
name: Ramireddy, Sriroopreddy
name: S., Udhaya Kumar
name: D., Thirumal Kumar
name: Tayubi, Iftikhar Aslam
name: Zayed, Hatem
name: C., George Priya Doss
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Chemical Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by insufficient aspartylglucosaminidase (AGA) activity leading to chronic neurodegeneration. We utilized the PhosphoSitePlus tool to identify the AGA protein’s phosphorylation sites. The phosphorylation was induced on the specific residue of the three-dimensional AGA protein, and the structural changes upon phosphorylation were studied via molecular dynamics simulation. Furthermore, the structural behaviour of C163S mutation and C163S mutation with adjacent phosphorylation was investigated. We have examined the structural impact of phosphorylated forms and C163S mutation in AGA. Molecular dynamics simulations (200 ns) exposed patterns of deviation, fluctuation, and change in compactness of Y178 phosphorylated AGA protein (Y178-p), T215 phosphorylated AGA protein (T215-p), T324 phosphorylated AGA protein (T324-p), C163S mutant AGA protein (C163S), and C163S mutation with Y178 phosphorylated AGA protein (C163S-Y178-p). Y178-p, T215-p, and C163S mutation demonstrated an increase in intramolecular hydrogen bonds, leading to greater compactness of the AGA forms. Principle component analysis (PCA) and Gibbs free energy of the phosphorylated/C163S mutation structures exhibit transition in motion/orientation than Wild type (WT). T215-p may be more dominant among these than the other studied phosphorylated forms. It might contribute to hydrolyzing L-asparagine functioning as an asparaginase, thereby regulating neurotransmitter activity. This study revealed structural insights into the phosphorylation of Y178, T215, and T324 in AGA protein. Additionally, it exposed the structural changes of the C163S mutation and C163S-Y178-p of AGA protein. This research will shed light on a better understanding of AGA’s phosphorylated mechanism. Communicated by Ramaswamy H. Sarma
Delta esuriens subsp. esuriens ssp. esuriens (Fabricius 1787
Creators: name: Carpenter, James M.
name: Gadallah, Neveen S.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Vespidae
Delta
Delta esuriens
Delta esuriens ssp. esuriens (fabricius, 1787)

description: Delta esuriens ssp. esuriens (Fabricius, 1787)
Distribution in the Arabian Peninsula: Kuwait (Walker & Pittaway 1987 as Delta campaniforme (Fabricius, 1775); Al-Houty 1989, 1997 both as D. campaniforme), Oman (Giordani Soika 1957 as D. campaniforme esuriens; Walker & Pittaway 1987 as D. campaniforme; Castro & Dvořák 2009); Gusenleitner 2004, 2005, 2013), Qatar (Giordani Soika 1957 as D. c. esuriens), Saudi Arabia (Walker & Pittaway 1987 as D. campaniforme; Gadallah 2003; Castro & Dvořák 2009; Gusenleitner 2013), United Arab Emirates (Gillett & Howarth 2004 as D. campaniforme; Gillett & Gillett 2005 as D. campaniforme; Howarth & Gillett 2008 as D. campaniforme; Gusenleitner 2010; Gess & Roosenschoon 2016).
Extralimital distribution: India, Iran, Iraq, Israel, Laos, Malaysia, Mauritius, Myanmar, New Caledonia, Pakistan, Sri Lanka, Thailand, Vietnam.
description: Published as part of Carpenter, James M. & Gadallah, Neveen S., 2020, Biodiversity of the aculeate wasps (Hymenoptera: Aculeata) of the Arabian Peninsula: Vespoidea, Vespidae, pp. 191-216 in Zootaxa 4754 (1) on page 197, DOI: 10.11646/zootaxa.4754.1.20, http://zenodo.org/record/3719047
Sonnenfleckenzeichnung Nr. 280.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.11.1962, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 1962

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf dem Vordruck der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert
description: ETH-Bibliothek