cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
New Tool For Treatment Of Obesity And Type 2 Diabetes: Lipidized Prolactin-Releasing Peptide Analogs
Creators: name: Popelov?, Andrea
Publisher: name: Zenodo
Year: 2016
Subjects: obesity
type 2 diabetes

description: Obesity is a frequent metabolic disorder with a steadily increasing prevalence worldwide. As obesity triggers other life-threatening diseases, including type 2 diabetes mellitus, hypertension, dyslipidemia and atherosclerosis, an effective therapy is needed. Anorexigenic neuropeptides have the potential to decrease food intake and ameliorate obesity and accompanying metabolic disturbances but are ineffective after peripheral application. We have designed several lipidized analogs of neuropeptide prolactin-releasing peptide (PrRP) which is involved in food intake regulation.  Our PrRP analogs with palmitic acid attached through glutamic acid or short chain of polyethylene glycol at Lys11 showed binding affinity and signaling in cells with PrRP receptor similar to natural PrRP. Furthermore, peripheral administration of these analogs to free fed mice and rats induced strong and long-lasting anorexigenic effect and neuronal activation in the brain areas involved in food intake regulation. Moreover, these novel analogs revealed higher bioavailability compared to PrRP analogs palmitoylated at N-terminus without any linker, probably due to higher solubility and better absorption after subcutaneous administration in mice and rats. Finally, food intake and body weight decrease as well as improvement of glucose tolerance were observed in diet-induced mice and obese diabetic rats after chronic treatment with palmitoylated PrRP analogs.        Our data suggest that lipidization of PrRP enhances its stability, as well as enables the peptide to cross blood-brain barrier after peripheral administration. Strong anorexigenic and body-weight-reducing effects make lipidized PrRP analogs attractive candidates for anti-obesity and anti-diabetic treatment.
title: Machine Learning Aided Column Generation for Solving Transmission Network Expansion Planning
Creators: name: Oteíza Canales, Pablo
Publisher: name: Federico Santa María Technical University
publisherIdentifier: https://ror.org/05510vn56
publisherIdentifierScheme: ROR
Year: 2024
Subjects: classificationCode: 2.2
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: Machine learning
subject: Decomposition techniques
subject: Energy transition

description: The global energy transition towards low-carbon economies has placed the power sector at the forefront of efforts to reduce emissions and address climate change, primarily through the large-scale integration of renewable energy. In Chile, this transition is guided by an energy policy targeting carbon neutrality by 2040 and a 100% renewable electricity supply by 2050. However, one of the major challenges lies in the timely development of transmission infrastructure, which is critical to integrate variable renewable energy (VRE) efficiently. The increasing difficulty of building new transmission lines due to environmental, social, and regulatory barriers has highlighted the potential of flexible technologies such as line reconductoring, FACTS, battery energy storage systems (BESS), and HVAC-HVDC conversion. This study addresses the transmission network expansion planning (TNEP) problem using an optimization-based framework that incorporates such technologies and accounts for the growing uncertainty in renewable expansion. It explores the shift from deterministic to stochastic and robust formulations, emphasizing the increasing computational complexity of TNEP in large-scale systems. This is especially true when emerging technologies are included, requiring time-coupling constraints and higher temporal resolution to properly model their impact. This work aims to support the development of efficient methodologies that guide cost-effective and secure decisions for a sustainable energy transition.
E05496: Leo the Great preaches a Latin sermon in the church of Saint *Anastasia (martyr of Sirmium and Rome, S00602) in Rome in 457.
Creators: name: Frances
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Leo the Great, Sermon 96

Summary:

This sermon is entitled:

Tractatus Beati Leoni Papae Contra Haeresim Euthichis. Dictus ad populum in basilica Sanctae Anastasiae.

'A tract of the blessed Pope Leo against the heretic Euthyches. Given to the people in the basilica of Saint Anastasia.'

Throughout the rest of the sermon Leo speaks out against the teachings of Euthyches. Anastasia is not mentioned again.

Text: Chavasse 1973. Translation and Summary: Frances Trzeciak.
Court-Annexed Mediation Practice in Malaysia: What the Future Holds
Creators: name: Yeow Choy, Choong
name: Fatt Hee, Tie
name: Ooi Su Siang, Christina
Publisher: name: Department of Legal Studies. Alma Mater Studiorum - Università di Bologna
Year: 2017
Subjects: Court-Annexed; Mediation; Judges; Mediators

description: It is an indubitable fact that the use of mediation as a form of dispute resolution process has gained traction across the globe. More importantly, the practice of mediation has also been transformed through the establishment of several techniques for formalised mediation. This article will provide insights into one of these avenues for formalised mediation, namely, court-annexed mediation practice in Malaysia. It will first discuss the motivations that led to the introduction of such a programme. This will be followed by an analysis of the operational aspects of the practice. A matter of utmost importance concerns the role of the courts and the judiciary in court-annexed mediation and this aspect is considered in considerable detail. This article will then offer suggestions on how some of the challenges that exist and are inherent in this particular method of formalised mediation could be overcome. These views are expressed with the hope that court-annexed mediation can function as an effective alternative dispute resolution mechanism under the umbrella of the Malaysian courts. Last but not least, it is also hoped that the above deliberations will be a catalyst for further comparative research and debates concerning this increasingly imperative form of formalised mediation process across all jurisdictions.
description: University of Bologna Law Review, Vol 1, No 2 (2016)
GUT MICROBIAL INTERPLAY WITH SEX HORMONE HOMEOSTASIS
Creators: name: Clapp, Anna R
name: Cross, Tzu-Wen L.
Publisher: name: Purdue University Graduate School
Year: 2025
Subjects: classificationCode: 310703
subject: Microbial ecology
classificationCode: 310799
subject: Microbiology not elsewhere classified

description: The gut microbiome plays a pivotal role in host health through both its composition and metabolic functions. Notably, emerging evidence suggests a bi-directional relationship between the gut microbiome and sex steroid homeostasis. Studies have documented shifts in gut microbial communities following gonadectomy, and menopause, and additional research indicates that gut microbes can directly modify sex steroids through deconjugation and sterol conversions. However, the interplay between the gut microbiome and the hypothalamic-pituitary-gonadal (HPG) axis - the central regulator of sex steroid homeostasis - along with the microbiome's response to exogenous sex steroids, remains poorly understood. Moreover, the causal role of the microbiome in regulating sex steroid homeostasis has yet to be fully elucidated. Herein, we present evidence from both conventional and gnotobiotic mouse models demonstrating that the gut microbiome not only responds to changes in sex steroid homeostasis but can also influence hypothalamic-pituitary-gonadal (HPG) axis signaling, potentially through its impact on the host metabolome. We further show that upstream suppression of the HPG axis leads to rapid perturbations in the gut microbiota, and that this altered microbiome can, in turn, affect reproductive parameters governed by sex steroid homeostasis. Additionally, we provide evidence that exogenous sex steroids, delivered as oral contraceptives, induce time- and intestinal segment-specific alterations in the gut microbiome - changes that may contribute to oral contraceptive-associated metabolic stress. Given the gut microbiome’s highly responsive nature to external factors such as diet, environment, and lifestyle factors, understanding its interaction with sex steroid homeostasis could offer promising targets for the development of novel therapeutics and precision medicine strategies.
E05499: The Miracles of Saint Thekla recounts how *Thekla (follower of the Apostle Paul, S00092) protected and supported the general Satornilos/Saturninus, helping him to win a battle in the diocese of Oriens and warning him about an ambush against him. Written in Greek at Seleucia ad Calycadnum (southern Asia Minor) in the 470s.
Creators: name: Julia
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Miracles of Saint Thekla, 13

Summary:

There was a general, Satornilos, a pious, well born, and celebrated man. Among other deeds, he killed Severus who defiled sacred places, thereby freeing the churches from an enormous lawlessness. Also, he was sent by the emperor [Theodosius II, r. 408-450] with a large and well-trained army to the diocese of Oriens which was being plundered by brigands from a neighbouring land. When he was preparing for a battle, the martyr Thekla was by his side and shielded him and helped him to achieve victory. Once, she even warned him about a treacherous ambush by some of the plunderers, so he was able to guard himself against it and killed his enemies, so that none of them survived. Satornilos then consecrated offerings to the virgin Thekla with which he decorated her temple. They are still there and remind those who gaze at them of the miracle and of the martyr's benevolence and sympathy for those who love her.

Text: Dagron 1978. Summary: J. Doroszewska.
E05504: Leo the Great preaches a Latin sermon in Rome in 453 on the feast of Epiphany in which he praises the *Innocents (children killed on the orders of Herod, S00268).
Creators: name: Frances
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Leo the Great, Sermon 38

Summary:

Leo tells his congregation that on this day they must consider the children whom Herod ordered to be killed. These children should be praised. Indeed, 'in the killing of all the infants a pattern of martyrdom was set' (in occisione infantium cunctorum martyrum forma praecesserit).

Summary: Frances Trzeciak.
FROM PENCILS TO PURPOSE: EXPLORING JOURNALING AS AN ANTIRACIST INSTRUCTIONAL TOOL TO FOSTER PSYCHOLOGICAL SAFETY AND BELONGING
Creators: name: Nargiso Newton, Brianna
Publisher: name: ProQuest
Year: 2025
Subjects: classificationCode: 390302
subject: Early childhood education
classificationCode: 390304
subject: Primary education
classificationCode: 39
subject: Education

description: Feelings of psychological safety, belonging, and representation are critical for student engagement and motivation for learning. However, many Title I schools rely on deficit-framed approaches that have historically marginalized the voices and potential of students from historically resilient communities. These schools, often serving Black and Brown students, exist at the intersection of race and socioeconomic disparities, amplifying the impact of systemic inequities. In contrast, asset-based instructional practices offer a powerful alternative by recognizing and affirming students’ cultural strengths, centering their voices, and fostering inclusive environments where students feel seen, valued, and empowered. This study examined the impact of daily journaling as an asset-based practice on fostering a sense of belonging and psychological safety among Black and Brown students in a Title I school in a large urban district. Using a mixed-methods approach, data were collected through pre- and post-intervention student surveys, teacher surveys, and semistructured interviews with a participating teacher. Quantitative results indicated significant increases in students’ perceptions of belonging and psychological safety, with mean scores rising from 2.9 to 4.0 for belonging and from 2.7 to 4.5 for psychological safety. Qualitative findings provided further insight, revealing that students felt more “seen” and “valued” through journaling, which offered them a safe space for authentic self-expression. The participating teacher also reported a transformation in her approach, moving from teacher-led practices to student-centered practices that elevated student voice and agency. The findings suggest journaling not only enhanced trust, connection, and representation in the classroom but also contributed to a sustainable shift in teaching practices aimed at centering belonging and psychological safety. This study underscores the importance of integrating asset-based practices in professional learning programs and curriculum design to promote identity-affirming and psychologically safe learning spaces for Black and Brown students. By highlighting the positive impact of asset-based approaches, this research advocated for systemic changes that ensures all students can thrive academically and socially.
Additional file 1 of Debranching enzymes decomposed corn arabinoxylan into xylooligosaccharides and achieved prebiotic regulation of gut microbiota in broiler chickens
Creators: name: Wu, Wei
name: Zhou, Huajin
name: Chen, Yanhong
name: Guo, Yuming
name: Yuan, Jianmin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 1: Fig. S1. Diagram of the proportion of specific ADE treatments in the respective XOS components.
Additional file 1 of Integrating accompanying patients into clinical oncology teams: limiting and facilitating factors
Creators: name: Pomey, Marie-Pascale
name: Paquette, Jesseca
name: Nelea, Monica Iliescu
name: Vialaron, Cécile
name: Mourad, Rim
name: Bouchard, Karine
name: Normandin, Louise
name: Côté, Marie-Andrée
name: Desforges, Mado
name: Pomey-Carpentier, Pénélope
name: Fortin, Israël
name: Ganache, Isabelle
name: Régis, Catherine
name: Rosberger, Zeev
name: Charpentier, Danielle
name: Vachon, Marie-France
name: Bélanger, Lynda
name: Dorval, Michel
name: Ghadiri, Djahanchah P.
name: Lavoie-Tremblay, Mélanie
name: Boivin, Antoine
name: Pelletier, Jean-François
name: Fernandez, Nicolas
name: Danino, Alain M.
name: de Guise, Michèle
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
E05515: Hymn in honour of *Eulalia (virgin and martyr of Mérida, S00407) composed in Latin in Spain possibly in the 7th c.
Creators: name: Mszada
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Hymnodia Hispanica, Hymn 117

IN SANCTAE EVLALIAE. IN LAVDIBUS

(1) Laudem beate Eolalie
puro canamus pectore,
quam Xristus inter martires
casto sacrabit sanguine.

'(1) Let us sing with pure heart the praise of the blessed Eulalia whom Christ blessed with pure blood among the martyrs.'

There follow the relation of the incarceration of Eulalia (strophes 2–3, cf. Martyrdom of Eulalia 8). The judge demands that she sacrifice to the gods (strophe 4) but she refuses despite being flogged (strophe 5; cf. Martyrdom of Eulalia 9–10). She is tortured by fire (strophe 6; cf. Martyrdom of Eulalia 11), she dies and her soul goes to heaven (strophe 7–8). Two last strophes (9–10) are the praise of God in Trinity.

Text: Castro Sánchez 2010, 434-436. Translation and summary: M. Szada.
sj-docx-2-tej-10.1177_2041731421990842 – Supplemental material for Human engineered meniscus transcriptome after short-term combined hypoxia and dynamic compression
Creators: name: Szojka, Alexander RA
name: Marqueti, Rita de Cássia
name: Li, David Xinzheyang
name: Molter, Clayton W
name: Liang, Yan
name: Kunze, Melanie
name: Mulet-Sierra, Aillette
name: Jomha, Nadr M
name: Adesida, Adetola B
Publisher: name: SAGE Journals
Year: 2021
Subjects: Dentistry not elsewhere classified
Biological Sciences not elsewhere classified

description: Supplemental material, sj-docx-2-tej-10.1177_2041731421990842 for Human engineered meniscus transcriptome after short-term combined hypoxia and dynamic compression by Alexander RA Szojka, Rita de Cássia Marqueti, David Xinzheyang Li, Clayton W Molter, Yan Liang, Melanie Kunze, Aillette Mulet-Sierra, Nadr M Jomha and Adetola B Adesida in Journal of Tissue Engineering
sj-docx-1-joo-10.1177_1465312520988549 – Supplemental material for The Journal of Orthodontics: A cross-sectional survey of British Orthodontic Society members
Creators: name: Jennings, Rosalind
name: Jadbinder Seehra
name: Cobourne, Martyn T
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-joo-10.1177_1465312520988549 for The Journal of Orthodontics: A cross-sectional survey of British Orthodontic Society members by Rosalind Jennings, Jadbinder Seehra and Martyn T Cobourne in Journal of Orthodontics
Additional file 3 of Debranching enzymes decomposed corn arabinoxylan into xylooligosaccharides and achieved prebiotic regulation of gut microbiota in broiler chickens
Creators: name: Wu, Wei
name: Zhou, Huajin
name: Chen, Yanhong
name: Guo, Yuming
name: Yuan, Jianmin
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 3: Fig. S3. Ileal microbial community distribution heatmap at the genus level (top 35).
sj-pdf-1-ajs-10.1177_0363546520988039 – Supplemental material for Forces at the Anterior Meniscus Attachments Strongly Increase Under Dynamic Knee Joint Loading
Creators: name: Seitz, Andreas Martin
name: Schall, Florian
name: Hacker, Steffen Paul
name: Drongelen, Stefan Van
name: Wolf, Sebastian
name: Dürselen, Lutz
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_0363546520988039 for Forces at the Anterior Meniscus Attachments Strongly Increase Under Dynamic Knee Joint Loading by Andreas Martin Seitz, Florian Schall, Steffen Paul Hacker, Stefan van Drongelen, Sebastian Wolf and Lutz Dürselen in The American Journal of Sports Medicine
sj-docx-1-srd-10.1177_2378023120975594 – Supplemental material for Linked Lives and Childhood Experience of Family Death on Educational Attainment
Creators: name: Patterson, Sarah E.
name: Verdery, Ashton M.
name: Daw, Jonathan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-srd-10.1177_2378023120975594 for Linked Lives and Childhood Experience of Family Death on Educational Attainment by Sarah E. Patterson, Ashton M. Verdery and Jonathan Daw in Socius
E05524: Bede, in his Martyrology, records the feast on 5 February in Sicily of *Agatha (virgin and martyr of Catania, S00794). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

Non. Feb. Sanctae Agathae virginis in Sicilia, sub Quintiano consule, tempore Diocletiani: quae post alapas et carcerem, post equuleum et tortiones, post mamillarum abscisiones, sed a Domino sanationem, post volutationem in testulis et carbonibus, tandem in carcere consummata est.

'5 February. In Sicily, under the consul Quintianus, in the time of Diocletian [the feast] of St Agatha: who after blows to the face and imprisonment, after the rack and tortures, after the cutting off of her breasts and being healed by the lord, after rolling in burning coals and small potsherds, finally was made perfect in prison.'

Text: Quentin 1908, 57. Translation: Lifshitz 2000, 181, lightly modified.
E05525: Bede, in his Martyrology, records the feast on 14 February at Rome of *Valentinus (priest and martyr of Rome, buried on the via Flaminia, S00433). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

XVI. Kal. Mar. Natale sancti Valentini presbyteri, Romae: qui post multa sanitatum et doctrinae insignia, fustibus caesus, et sic decollatus est, sub Claudio Caesare.

'14 February. At Rome, the feast of St Valentinus, priest: who after many public signs of healing and erudition, having been beaten with clubs, was also in this way beheaded, under Claudius Caesar.'

Text: Quentin 1908, 87. Translation: Lifshitz 2000, 181, lightly modified.
sj-pdf-1-hej-10.1177_0017896921993846 – Supplemental material for Designing an interprofessional Facebook discussion group to teach about LGBTQ healthcare disparities and inclusive practices
Creators: name: Neill, Kathryn
name: M Kathryn Allison
name: Jarrett, Diane M
name: Masil George
name: Knight, Daniel
name: Ward, Wendy
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: Education

description: Supplemental material, sj-pdf-1-hej-10.1177_0017896921993846 for Designing an interprofessional Facebook discussion group to teach about LGBTQ healthcare disparities and inclusive practices by Kathryn Neill, M Kathryn Allison, Diane M Jarrett, Masil George, Daniel Knight and Wendy Ward in Health Education Journal
E05526: Bede, in his Martyrology, records the feast on 14 February of *Valentinus (bishop and martyr of Terni, S00434). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

XVI. Kal. Mar. Natale sancti Valentini Interamnensis episcopi: qui tentus a paganis ac vergis caesus, et post diuturnam caedam custodiae mancipatus, cum superari non posset, mediae noctis silentio eiectus de carcere decollatus est, iussu Furiosi Placidi, Urbis praefecti. Tunc Proculus, Efybus et Apollonius discipuli eius transferentes corpus ad suam ecclesiam Interamnanae urbis noctu, sepelierunt: ubi cum quotidianis vigiliis incubarent, tenti a gentilibus custodiae sunt traditi consulari Leontio: quos ille iussit medio noctis suis tribunalibus praesentari: et cum a fide revocari nec blandimentis nec minis possent, iussit capite caedi: qui non longe sunt a corpore sancti Valentini sepulti.

'14 February. The feast of St Valentinus bishop of Terni: who, detained by the pagans and beaten with rods and, after having been subjected to the long, slow slaughter of imprisonment, when he could not be vanquished, was tossed out of prison in the silence of the middle of the night and beheaded at the command of Furiosus Placidus, prefect of the city. Then Proclus, Efybus and Apollonius, his disciples, transferring his body by night to their church in the city of Terni, buried him: when they were abiding there with daily vigils, having been detained by the Gentiles, they were given over for guarding to the emperor's governing legate, Leontius: he ordered them to be presented before his tribunal in the middle of the night: and when they could not be called away from the faith either by allurements or by threats, he ordered them to have their heads cut off: they were buried not far from the body of St Valentinus.'

Text: Quentin 1908, 94. Translation: Lifshitz 2000, 181, modified.
Effects Of C-Peptide On Adipocytes And Mesenchymal Stem Cells In Human Adipose Tissue
Creators: name: Ghorbani, Ahmad
name: Shafiee-Nick, Reza
name: Seyyed Abbas Zojaji
name: Rajabi-Mashhadi, Mohammad Taghi
Publisher: name: Zenodo
Year: 2016
Subjects: Adipose tissue; Adiponectin; C-peptide; Stem cells

description: Recent studies suggest that proinsulin connecting peptide (C-peptide) may show physiological functions in various tissues. This study was aimed to determine whether C-peptide could be involved in the regulation of lipolysis, adiponectin release, and function of mesenchymal stem cells (MSCs) in adipose tissue. Human subcutaneous adipose tissue was cultured in the presence of C-peptide and lipolysis was determined by glycerol measurement in the conditioned media. Effect of C-peptide on adiponectin secretion was evaluated in differentiated adipocytes. The adipogenic and osteogenic abilities of adipose MSCs were evaluated using Oil Red and Alizarin Red staining, respectively. C-peptide induced a significant decrease in basal lipolysis, a slight decrease (statistically insignificant) in isoproterenol-stimulated lipolysis, and a slight increase in adiponectin secretion at concentration of 8 nM, 16 nM and 4 nM, respectively. It had no effect on adipogenic and osteogenic differentiation of MSCs. However, at concentration of 4 nM, C-peptide significantly increased the proliferative capability of MSCs (p<0.05). These results suggest that C-peptide has physiological effects in human subcutaneous adipose tissue and contributes to the regulation of basal lipolysis and pool of MSCs.
Additional file 1 of Revealing third-order interactions through the integration of machine learning and entropy methods in genomic studies
Creators: name: Yaldız, Burcu
name: Erdoğan, Onur
name: Rafatov, Sevda
name: Iyigün, Cem
name: Aydın Son, Yeşim
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Statistics
subject: FOS: Mathematics

description: Additional file 1: Supplementary Figure 1. The optimized mtry and ntree parameters are specified as 2 and 900 for GenADA dataset1. Supplementary Figure 2. The model optimized with the mtry and ntree parameters in the ADNI dataset, by considering the diagnostic model error rate with the 5-folds cross-validation. Optimum mtry and optimum ntree parameters are specified as 39 and 50 respectively. Supplementary Figure 3. The optimized mtry and ntree parameters are specified as 83 and 1000 respectively for NCRAD dataset. Supplementary Table 1. SNPs Selected through PLINK-RF-RF workflow. Supplementary Table 2. Triplets that are filtered as they include SNP pairs with significant 2WI in the NCRAD dataset. Supplementary Table 3. IIG Values for Prioritized GenADA Triplets. Supplementary Table 4. IIG Values for Prioritized ADNI Triplets. Supplementary Table 5. Test Statistics and Permutation Testing Results for NCRAD Dataset. Supplementary Table 6. Genes involved in functional enrichment analysis.
E05527: Bede, in his Martyrology, records the feast on 16 February at Cumae (southern Italy) of *Iuliana (martyr of Nicomedia, buried at Cumae, S01162). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

XIV. Kal. Mar. Et in Cumis, natale sanctae Iulianae virginis: quae, tempore Maximiani imperatoris, primo a suo patre Africano caesa et graviter cruciata, et a praefecto Eolesio, quem sponsum habuerat, nuda virgis caesa, et a capillis suspensa, et plumbo soluto a capite perfusa, et rursum in carcere recepta, ubi palam cum diabolo conflixit; et rursum evocata rotarum tormenta, flammas ignium, ollam ferventem superavit, ac decollatione capitis martyrium consummavit. Quae passa est quidem in Nicomedia: sed post paucum tempus, Deo disponente, in Campaniam translata.

'16 February. And in Cumae, the feast of St Iuliana, virgin: who, in the time of the emperor Maximianus, having first been beaten and seriously afflicted by her father Africanus, and having been beaten, naked, with rods and hung up by her hair, and drenched from her head down with molten lead by the prefect Eolesius, to whom she was betrothed, and having been taken back again into prison where she openly contested with the devil; and having been called back out again, she vanquished the torments of torture wheels, the flames of fires, a boiling-hot pot and accomplished martyrdom by the cutting off of her head. Indeed, she suffered in Nicomedia; but after a short time, through God's disposition, she was transferred into Campania.'

Text: Quentin 1908, 77. Translation: Lifshitz 2000, 181-2, modified.
E05528: Bede, in his Martyrology, records the feast on 17 February in Babylon (Persia) of *Polychronius (bishop and martyr of Babylon, S01391). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

XIII. Kal. Mar. In Babylonia, natale Polocronii episcopi eiusdem civitatis: qui, praesente Decio persecutore, os lapidibus caesus, manibus extensis, oculos ad caelos elevans, emisit spiritum. Scriptum in passione sancti Laurentii.

'17 February. In Babylon, the feast of Polychronius, bishop of that same city: who, in the presence of the persecutor Decius, his face having been crushed with stones, with his hands outstretched, lifting his eyes to heaven, sent forth his spirit. It is written in the Martyrdom of Saint Laurence.'

Text: Quentin 1908, 78. Translation: Lifshitz 2000, 182, modified.
E05533: Bede, in his Martyrology, records the feast on 9 March in Sebaste (eastern Asia Minor) of the *Forty Martyrs of Sebaste (S00103). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

VII. Id. Mar. In Sebaste, in Armenia minore, quadraginta militum, tempore Licinii regis, sub praeside Agricolao: qui post vincula et carceres creberrimos, post caesas lapidibus facies, missi sunt in stagnum: ubi gelu constricta corpora eorum noctu disrumpebantur, et mane crurifragio martyrium consummarunt. Deinde corpora eorum combusta et in flumen proiecta; sed dispensatione divina reliquiae eorum sunt integrae repertae et digno honore conditae. Erant autem nobiliores inter eos Quirion et Candidus.

'9 March. In Sebaste, in Lesser Armenia, in the time of King Licinius, under the governor Agricolaos, [the feast] of the forty soldiers, who after chains and repeated imprisonments, after having their faces beaten with stones, were placed in a lake: where their bodies, contracted by the cold, were bursting asunder during the night, and in the morning they accomplished martyrdom by the breaking of their shins. Then their bodies were burned and tossed into the river; but due to divine direction their relics were found unmutilated and were buried with worthy honour. Moreover the more noble among them were Quirion and Candidus.'

Text: Quentin 1908, 90. Translation: Lifshitz 2000, 182, lightly modified.
Supplemental Material, sj-pdf-1-hme-10.1177_2333392820986639 - Characteristics of the First 102 Severe COVID-19 Cases Treated With Convalescent Plasma or Tocilizumab or Both in Al-Nahdha Hospital, Oman
Creators: name: Saud Al Harthi
name: Magdi Al Osali
name: Kindi, Nasser Al
name: Kharusi, Zahir Al
name: Qasabi, Salim Al
name: Hinai, Mohamed Al
name: Thamra Al Ghafri
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, sj-pdf-1-hme-10.1177_2333392820986639 for Characteristics of the First 102 Severe COVID-19 Cases Treated With Convalescent Plasma or Tocilizumab or Both in Al-Nahdha Hospital, Oman by Saud Al Harthi, Magdi Al Osali, Nasser Al Kindi, Zahir Al Kharusi, Salim Al Qasabi, Mohamed Al Hinai and Thamra Al Ghafri in Health Services Research and Managerial Epidemiology
E05532: Bede, in his Martyrology, records the feast on 7 March at Carthage of *Perpetua and Felicitas (martyrs of Carthage, S00009). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

Non. Mar. Apud Carthaginem Perpetuae et Felicitatis, quae bestiis sunt deputatae, sub Severo principe: et, cum Felicitas parturiret in carcere, omnium militum qui simul patiebantur precibus impetratum est ut octavo mense pareret. Iamvero Perpetua inter alia concessum est ut eius mens quodammodo averteretur a corpore, in quo vaccae impetum pertulit: ita ut adhuc futurum exspectaret quod in se iam gestum esse nesciret.

'7 March. At Carthage, [the feast] of Perpetua and Felicitas, who were condemned to the beasts, under the princeps Severus: and since Felicitas was pregnant in prison, it was procured by the prayers of the soldiers [of Christ] who were likewise suffering that she would give birth in the eighth month. Truly, among other things it was granted to Perpetua that her mind would somehow be turned away from her body, in which she endured the attack of a cow: in this way, in order that she might look forward to what was to come, she did not know what was happening while she was still in herself.'

Text: Quentin 1908, 88. Translation: Lifshitz 2000, 182, lightly modified.
sj-docx-4-sph-10.1177_1941738121991782 – Supplemental material for Return to Play After Symptomatic Lumbar Disc Herniation in Elite Athletes: A Systematic Review and Meta-analysis of Operative Versus Nonoperative Treatment
Creators: name: Phelopater Sedrak
name: Shahbaz, Mustafa
name: Chetan Gohal
name: Madden, Kim
name: Aleem, Ilyas
name: Khan, Moin
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine

description: Supplemental material, sj-docx-4-sph-10.1177_1941738121991782 for Return to Play After Symptomatic Lumbar Disc Herniation in Elite Athletes: A Systematic Review and Meta-analysis of Operative Versus Nonoperative Treatment by Phelopater Sedrak, Mustafa Shahbaz, Chetan Gohal, Kim Madden, Ilyas Aleem and Moin Khan in Sports Health: A Multidisciplinary Approach
E05534: Bede, in his Martyrology, records the feast on 16 March at Rome of *Cyriacus (martyr of Rome, S00678). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

XVII Kl. Apr. Romae, natale sancti Cyriaci, qui post longam carceris macerationem, quam sub Maximiano pertulit, cum Sisinnio condiacono suo et Smaragdo et Largo, post multa facta miracula, in quibus filiam Diocleriani Artemiam, ipsius rogatu, a daemonio curavit et baptizavit, filiam quoque Saporis regis Persarum Iobiam, missus illuc a Diocelatiano pro hoc, aeque a daemonio liberavit ac baptizavit, cum ipso rege et aliis quadringentis triginta. Rediens Romam, post mortem Diocletiani tentus est inter alios christianos a filio eius Maximiano, et in custodiam missus, eo quod sororem suam christianum fecisst. Deinde praecepit ut die processionis suae nudus, catenis obligatus, ante rhedam eius traheretur: et post haec eductus st e carcere cum sociis Largo et Smaragdo et Crescentiano per Carpasium vicarium, et pice reliquata caputa eius perfusum est. Et rursus post dies quatour, eductus denuo in carcere, in catasta extentus, attractus nervis et fustibus caesus; post hoc iubente Maximiano capite truncatus est, cum Largo et Smaragdo et aliis viginti. Scriptum in gestis Marcelli papae. Ipso tempore Maximianus interfecit sororem suam Artemiam.

'16 March. At Rome, the feast of St Cyriacus who, after wasting away under long imprisonment, which he endured under Maximianus, with Sisinnius his fellow deacon and Smaragdus and Largus, after many miracles had been done, among which he cured of a demon and baptised Artemia, the daughter of Diocletian, at that very man's request, and baptised her; also liberated from a demon Iobe, the daughter of Sapor king of the Persians, having been sent there precisely for that purpose by Diocletian, and baptised her, along with the king himself and another four hundred and forty people. Returning to Rome after the death of Diocletian, he was detained along with other Christians by his son Maximianus, and taken into custody, because he had made his sister a Christian. Then [Maximianus] commanded that he be dragged before his carriage on the day of his procession, naked and loaded with chains, having been led out from the prison along with his companions Largus and Smaragdus and Crescentianus by the deputy Carpasius, his head was also drenched with melted pitch. And then again after four days, having been led out once more from prison, he was stretched out on a scaffold, drawn with tight fetters and beaten with clubs; after this his head was cut off, along with Largus and Smaragdus and twenty others, on the command of Maximianus. It is written in the deeds of Pope Marcellus. At that same time Maximianus killed his sister Artemia.'

Text: Quentin 1908, 83-4. Translation: Lifshitz 2000, 182-3, modified.
Supplementary Material 2 - Supplemental material for Systematic Review of Interventions to Increase Awareness of Ultraviolet Radiation-Induced Harm and Protective Behaviors in Post-Secondary School Adults
Creators: name: Asai, Yuka
name: Armstrong, Dawn
name: McPhie, Meghan L
name: Xue, Chao
name: Rosen, Cheryl F
Publisher: name: SAGE Journals
Year: 2021
Subjects: Medicine

description: Supplemental material, Supplementary Material 2, for Systematic Review of Interventions to Increase Awareness of Ultraviolet Radiation-Induced Harm and Protective Behaviors in Post-Secondary School Adults by Yuka Asai, Dawn Armstrong, Meghan L McPhie, Chao Xue and Cheryl F Rosen in Journal of Cutaneous Medicine and Surgery
E05535: Bede, in his Martyrology, records the feast on 25 March of *Dula (martyr of Nicomedia, S00991). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bryan
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

VIII Kl. Apr. Natale Dulae ancillae militis, quae pro castitate occisa est.

'25 March. The feast of Dula, maidservant of a soldier, who was killed for the sake of chastity.'

Text: Quentin 1908, 110. Translation: Lifshitz 2000, 183, lightly modified.
Additional file 2 of The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma
Creators: name: Hayakawa, Mineji
name: Tagami, Takashi
name: Kudo, Daisuke
name: Ono, Kota
name: Aoki, Makoto
name: Endo, Akira
name: Yumoto, Tetsuya
name: Matsumura, Yosuke
name: Irino, Shiho
name: Sekine, Kazuhiko
name: Ushio, Noritaka
name: Ogura, Takayuki
name: Nachi, Sho
name: Irie, Yuhei
name: Hayakawa, Katsura
name: Ito, Yusuke
name: Okishio, Yuko
name: Muronoi, Tomohiro
name: Kosaki, Yoshinori
name: Ito, Kaori
name: Nakatsutsumi, Keita
name: Kondo, Yutaka
name: Ueda, Taichiro
name: Fukuma, Hiroshi
name: Saisaka, Yuichi
name: Tominaga, Naoki
name: Kurita, Takeo
name: Nakayama, Fumihiko
name: Shibata, Tomotaka
name: Kushimoto, Shigeki
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 2. Participating institutions and corresponding Ethics Committees
E05536: Bede, in his Martyrology, records the feast on 25 March at Rome of *Cyrinus/Quirinus (martyr of Rome, buried in the cemetery of Pontianus, on the via Portuensis, S01551). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

VIII Kl. Apr. Romae, Cyrini qui interfectus a Claudio et in Tiberim iactatus, in insula Lycaonia inventus, et in coemeterio Pontiani conditus est. Scriptum in passione sancti Valentini.

'25 March. At Rome, [the feast] of Cyrinus, who was slain by Claudius and thrown into the Tiber, discovered on the island of Lycaonia, and buried in the cemetery of Pontianus. It is written in the Martyrdom of Saint Valentinus.'

Text: Quentin 1908, 87. Translation: Lifshitz 2000, 183, modified.
Additional file 1 of The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma
Creators: name: Hayakawa, Mineji
name: Tagami, Takashi
name: Kudo, Daisuke
name: Ono, Kota
name: Aoki, Makoto
name: Endo, Akira
name: Yumoto, Tetsuya
name: Matsumura, Yosuke
name: Irino, Shiho
name: Sekine, Kazuhiko
name: Ushio, Noritaka
name: Ogura, Takayuki
name: Nachi, Sho
name: Irie, Yuhei
name: Hayakawa, Katsura
name: Ito, Yusuke
name: Okishio, Yuko
name: Muronoi, Tomohiro
name: Kosaki, Yoshinori
name: Ito, Kaori
name: Nakatsutsumi, Keita
name: Kondo, Yutaka
name: Ueda, Taichiro
name: Fukuma, Hiroshi
name: Saisaka, Yuichi
name: Tominaga, Naoki
name: Kurita, Takeo
name: Nakayama, Fumihiko
name: Shibata, Tomotaka
name: Kushimoto, Shigeki
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 1. Original protocol translated into English
E05537: Bede, in his Martyrology, records the feasts on 1 and 5 April in Thessalonike (northern Greece) of *Agape, Chione and Eirene (martyrs of Thessalonike, S00206). Written in Latin at Wearmouth-Jarrow (north-east Britain), 725/731.
Creators: name: Bsavill
Publisher: name: University of Oxford
Year: 2018
Subjects: History

description: Bede, Martyrology

Kl. Apr. In Thessalonica, natale Agapis et Chioniae sub Diocletiano, quae primo in carcere maceratae, post in ignem missae sunt, sed intactae a flammis, post orationem ad dominum fusam, animas reddiderunt.

/Non. Apr. In Thessalonica, natale Irenes quae post tolerantiam carceris, inter orationes sagitta percussa est a Sisinnio comite: sub quo et sorores eius Agape et Chionia martyrizaverunt.

'1 April. At Thessalonica, the feast of Agape and Chione who, under Diocletian, first wasted away in prison, then were sent into the fire but, untouched by the flames, rendered up their souls after having poured forth a prayer to the Lord.

/5 April. In Thessalonica, the feast of Eirene who, after suffering imprisonment, amidst prayers was pierced through by an arrow by the comes Sisinnius, under whom her sisters Agape and Chionia also achieved martyrdom.'

Text: Quentin 1908, 59. Translation: Lifshitz 2000, 183, modified.
Additional file 7 of The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma
Creators: name: Hayakawa, Mineji
name: Tagami, Takashi
name: Kudo, Daisuke
name: Ono, Kota
name: Aoki, Makoto
name: Endo, Akira
name: Yumoto, Tetsuya
name: Matsumura, Yosuke
name: Irino, Shiho
name: Sekine, Kazuhiko
name: Ushio, Noritaka
name: Ogura, Takayuki
name: Nachi, Sho
name: Irie, Yuhei
name: Hayakawa, Katsura
name: Ito, Yusuke
name: Okishio, Yuko
name: Muronoi, Tomohiro
name: Kosaki, Yoshinori
name: Ito, Kaori
name: Nakatsutsumi, Keita
name: Kondo, Yutaka
name: Ueda, Taichiro
name: Fukuma, Hiroshi
name: Saisaka, Yuichi
name: Tominaga, Naoki
name: Kurita, Takeo
name: Nakayama, Fumihiko
name: Shibata, Tomotaka
name: Kushimoto, Shigeki
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 7. Survival, complications, and event-free days in the per-protocol analysis
sj-pdf-1-cph-10.1177_1715163520981397 – Supplemental material for Pharmacists’ knowledge, experiences and perceptions of treatments for attention-deficit/hyperactivity disorder
Creators: name: Yuen, Terence
name: Hantao Zhang
name: Bonin, Robert P.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-cph-10.1177_1715163520981397 for Pharmacists’ knowledge, experiences and perceptions of treatments for attention-deficit/hyperactivity disorder by Terence Yuen, Hantao Zhang and Robert P. Bonin in Canadian Pharmacists Journal / Revue des Pharmaciens du Canada
Additional file 1 of Non-communicable disease burden among inpatients at a rural district hospital in Malawi
Creators: name: Olds, Peter
name: Kachimanga, Chiyembekezo
name: Talama, George
name: Mailosi, Bright
name: Ndarama, Enoch
name: Totten, Jodie
name: Musinguzi, Nicholas
name: Hangiwa, Dickson
name: Bukhman, Gene
name: Wroe, Emily B.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Cancer

description: Additional file 1. Figure S1. Age distribution of patients with or without an NCD diagnosis. Box plot of age distribution of patients who did or did not carry an NCD diagnosis. Boxes show the 25th and 75th percentiles, and whiskers convey the upper and lower adjacent values, with dots representing outliers. NCD Non-communicable disease. Figure S2. Age distribution of patients by number of unique NCD diagnoses. Box plot representing the age distribution for the number of total NCD diagnoses a patient carried. Boxes show the 25th and 75th percentiles, and whiskers convey the upper and lower adjacent values, with dots representing outliers. NCD Non-communicable disease.
sj-pdf-1-eso-10.1177_2396987321994294 - Supplemental material for Cerebrovascular disease in patients with cognitive impairment: A white paper from the ESO dementia committee – A practical point of view with suggestions for the management of cerebrovascular diseases in memory clinics
Creators: name: Verdelho, Ana
name: Biessels, Geert Jan
name: Chabriat, Hugues
name: Charidimou, Andreas
name: Duering, Marco
name: Godefroy, Olivier
name: Pantoni, Leonardo
name: Pavlovic, Aleksandra
name: Wardlaw, Joanna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-eso-10.1177_2396987321994294 for Cerebrovascular disease in patients with cognitive impairment: A white paper from the ESO dementia committee – A practical point of view with suggestions for the management of cerebrovascular diseases in memory clinics by Ana Verdelho, Geert Jan Biessels, Hugues Chabriat, Andreas Charidimou, Marco Duering, Olivier Godefroy, Leonardo Pantoni, Aleksandra Pavlovic and Joanna Wardlaw in European Stroke Journal
Additional file 3 of The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma
Creators: name: Hayakawa, Mineji
name: Tagami, Takashi
name: Kudo, Daisuke
name: Ono, Kota
name: Aoki, Makoto
name: Endo, Akira
name: Yumoto, Tetsuya
name: Matsumura, Yosuke
name: Irino, Shiho
name: Sekine, Kazuhiko
name: Ushio, Noritaka
name: Ogura, Takayuki
name: Nachi, Sho
name: Irie, Yuhei
name: Hayakawa, Katsura
name: Ito, Yusuke
name: Okishio, Yuko
name: Muronoi, Tomohiro
name: Kosaki, Yoshinori
name: Ito, Kaori
name: Nakatsutsumi, Keita
name: Kondo, Yutaka
name: Ueda, Taichiro
name: Fukuma, Hiroshi
name: Saisaka, Yuichi
name: Tominaga, Naoki
name: Kurita, Takeo
name: Nakayama, Fumihiko
name: Shibata, Tomotaka
name: Kushimoto, Shigeki
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: Additional file 3. Number of patients included in each institution