cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Association between cardiac, renal, and hepatic biomarkers and outcomes in patients with acute heart failure
Creators: name: Chan, Wing W.
name: Johnson, Katherine Waltman
name: Friedman, Howard S.
name: Navaratnam, Prakash
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 60506 Virology

description: Objectives: Myocardial injury, worsening renal function, and hepatic impairment are independent risk factors for poor patient acute heart failure (AHF) outcomes. Biomarkers of organ damage may be useful in identifying patients at risk for poor outcomes. The objective of this analysis was to assess the relationship between abnormal AHF biomarkers and outcomes in AHF patients. Methods: AHF admissions (N = 104,794) data from the Cerner Health Facts® inpatient database were analyzed retrospectively. Multivariate predictive models determined the impact of biomarkers on mortality, readmission, length of stay (LOS), and cost from index admission through 180 days post discharge. Thirty and 60 day time windows are reported but 180 day results were consistent with 60 day outcomes. Biomarkers evaluated were aspartate transaminase (AST), estimated glomerular filtration rate (eGFR), high sensitivity cardiac troponin, bilirubin, alanine transaminase (ALT), sodium, high sensitivity C-reactive protein (hs-CRP), uric acid, B-type natriuretic peptide (BNP), NT-ProBNP, blood urea nitrogen (BUN), serum creatinine (SCr), and hemoglobin. Results: All biomarkers evaluated except hs-CRP, uric acid, and NT-ProBNP were significant (p Conclusions: Renal function measures were associated with outcomes in patients hospitalized for AHF. Increased vigilance of renal biomarkers may be warranted to assess risk and promote proactive clinical management to improve outcomes.
title: 03_0584
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
ПРОДУКТИВНОСТЬ И КАЧЕСТВО СЕМЯН СОРТОВ ГОРЧИЦЫ В ЗАВИСИМОСТИ ОТ МИНЕРАЛЬНОГО ПИТАНИЯ И ПРИМЕНЕНИЯ УДОБРЕНИЙ
Creators: name: Нурманов Ербол Толешович
name: Хамзина Бибигуль Нуркеновна
Publisher: name: Международный сельскохозяйственный журнал
Year: 2020
Subjects: горчица
сорта
нитратный азот
подвижный фосфор
минеральные удобрения
чернозем южный
урожайность

description: Горчица является ценным источником получения высококачественного масла, обладает фитомелиоративными и фитосанитарными свойствами, широко используется в разных отраслях промышленности. В данное время мало изучены требования горчицы к минеральному питанию почвы и минеральным удобрениям, что и являлось целью наших исследований. Исследования проводились на черноземе южном карбонатном степной зоны Казахстана. Опыты закладывались по 14 вариантной схеме, где предусматривалось создание различных уровней содержания в почве фосфора и азота (от низкого до избыточно высокого) с целью установления количественной взаимосвязи между уровнем содержания элементов питания в почве и продуктивностью сортов горчицы. Результаты исследования показали, что наилучший результат достигался разными дозами внесенных удобрений. Из-за низкой продуктивной влаги в почве азотные удобрения не дали должного эффекта. Наилучшие результаты получены по фонам фосфора. С увеличением содержания подвижного фосфора в почве повысилась продуктивность горчицы, прибавка составила от 1,0 до 6,6 ц/га. Азотные удобрения не способствовали повышению жира зерна горчицы, наблюдалась тенденция к его снижению независимо от уровня обеспеченности почв азотом. Фосфорные удобрения положительно влияли на накопление жира. Содержание жира варьировала от 28,6 до 30,4% по сорту Рушена, 35,6-37,5% — по сорту Профи. Наилучшие результаты получены по вариантам Р120-Р150, что говорит о разных требованиях сортов горчицы на почвенные условия. Расчеты экономической эффективности показали, что применение удобрений под горчицу высокоокупаемы. Таким образом, проведенные исследования показали отзывчивость сортов горчицы на азотно-фосфорные удобрения в зависимости от содержания элементов питания в почве. Эффективность применяемых удобрений определяется уровнем содержания элементов питания в почве, условиями влагообеспеченности, температурным режимом и биологическими особенностями сортов горчицы.
Efficacy, safety and effectiveness of ondansetron compared to other serotonin-3 receptor antagonists (5-HT3RAs) used to control chemotherapy-induced nausea and vomiting: systematic review and meta-analysis
Creators: name: Giovana Paula Rezende Simino
name: Lays Pires Marra
name: Andrade, Eli Iola Gurgel De
name: Acúrcio, Francisco De Assis
name: Reis, Ilka Afonso
name: Vânia Eloisa De Araújo
name: Mariângela Leal Cherchiglia
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy

description: Introduction: Chemotherapy-induced nausea and vomiting are adverse effects responsible for worsening quality of life in cancer patients. To assess the efficacy, safety and effectiveness of serotonin receptor antagonist in cancer patients undergoing chemotherapy, comparing ondansetron with granisetron, dolasetron, tropisetron and palonosetron. Areas covered: Systematic review and meta-analysis. The data were collected using CINAHL; CENTRAL; MEDLINE/PubMed; and LILACS databases; grey literature; and manual search. The methodological quality was assessed using the modified Jadad scale; Cochrane Collaboration’s tool for assessing risk of bias in randomized clinical trials and the Newcastle-Ottawa Scale for observational studies. The search was completed in November, 2015. 26 studies were included in the meta-analysis. Ondansetron exhibited similar efficacy than granisetron and tropisetron, as well as greater efficacy than dolasetron for acute vomiting. Palonosetron exhibited greater efficacy than ondansetron for delayed nausea and acute and delayed vomiting. The comparison of granisetron with ondansetron in the cohort studies showed no difference. Expert commentary: In this review, palonosetron had increased efficiency compared with ondansetron, except in the subgroup analysis and acute nausea. Few cohort studies have been published addressing this topic.
КОНКУРСНОЕ СОРТОИСПЫТАНИЕ И ЖИРНОКИСЛОТНЫЙ СОСТАВ МАСЛА СОРТООБРАЗЦОВ ЛЬНА МАСЛИЧНОГО (LINUM USITATISSIMUM L.)
Creators: name: Бражников Владимир Николаевич
name: Бражникова Ольга Федоровна
Publisher: name: Международный сельскохозяйственный журнал
Year: 2020
Subjects: лён масличный (Linum usitatissimum L)
сорт
селекция
продуктивность
масличность
сбор масла
стабильность
жирнокислотный состав масла.

description: Лён — одно из ценных сельскохозяйственных растений. По биологической ценности льняное масло занимает первое место среди других пищевых растительных масел. Различное соотношение жирных кислот позволяет его использовать для пищевых и технических целей. Цель исследований — провести комплексную оценку сортообразцов льна масличного собственной селекции в конкурсном сортоиспытании для создания сортов с различным жирнокислотным составом масла (ЖКС), сочетающих высокую продуктивность, масличность, скороспелость, устойчивость к полеганию. Эксперименты выполняли в ФГБНУ «Пензенский НИИСХ» в 2015-2017 гг. Материал для исследования — 12 сортообразцов собственной селекции. Стандартом служили сорта ВНИИМК-622 и Исток. При проведении исследований использовали «Методику государственного сортоиспытания сельскохозяйственных культур». Идентификацию и определение содержания высокомолекулярных жирных кислот выполняли методом газожидкостной хроматографии на хроматографе «Кристалл 5000.1». В результате исследований выделен скороспелый образец К-9/23-12, созревающий на 3-5 суток раньше стандарта ВНИИМК-622. По комплексу основных хозяйственно полезных признаков выделены ценные образцы 281/52, К-9/23-29, К-9/23-16-1 с урожайностью 1,80, 1,76, 1,72 т/га, масличностью — 44,42, 44,10, 43,98% и сбором масла — 658,1, 642,5, 663,1 кг/га соответственно. Выявлены наиболее стабильные сортообразцы: по семенной продуктивности — К-9/23-12 (V=9,0%), по масличности — К-9/23-16-1 (V=0,8%) и 281/52 (V=1,2%), по сбору масла — К-9/23-12 (V=3,8%). Созданы генотипы с традиционным ЖКС масла К-9/23-12 и К-9/23-12-3 (линоленовой кислоты — 54,9, 53,2%, линолевой кислоты — 15,9, 17,1%), с измененным ЖКС масла 281/52, К-9/23-29, 208/4, 105/46, и К-9/23-16-1 (линолевой кислоты — 54,6-68,3%, линоленовой кислоты — 4,9-18,5%) и сортообразцы 241/12, 261/32 и 205/1 с промежуточным ЖКС (линолевой кислоты — 25,4-49,1%, линоленовой кислоты — 24,0-46,9%).
ФОРМИРОВАНИЕ ПОДЗЕМНЫХ МЕЖДОУЗЛИИ ОВСА С ВЛИЯНИЕМ ГИДРОТЕРМИЧЕСКОГО КОЭФФИЦИЕНТА МЕТЕОУСЛОВИЙ ЯКУТИИ НА УСТОЙЧИВОСТЬ к полеганию В ФАЗЕ СОЗРЕВАНИЯ ЗЕРНА ОВСА
Creators: name: Петрова Лидия Владимировна
Publisher: name: Международный сельскохозяйственный журнал
Year: 2020
Subjects: овес посевной
новый сорт
урожайность зерна
эпикотель
кущение
всходы
этапы органогенеза хлебных злаков

description: В статье приведены результаты оценки роста подземного междоузлия овса К-4880 и Покровский в гидротермических условиях Якутии в увлажненный и засушливый годы. При выращивании овса в условиях короткого лета Якутии на рост и развитие растений овса посевного могут влиять абиотические факторы среды [7]. Цель исследований — определить длину подземного междоузлия овса посевного К-4880 в сравнении со стандартным сортом овса Покровский в условиях Центральной Якутии для оценки признака полегаемости в фазе созревания зерна овса. Результаты изучения показали, что овес К-4880 на ранних этапах органогенеза способен замедлить рост длины подземного междоузлия до 0,3 см, стандартный сорт овса Покровский, развивает рост до 1,5 см. При определении взаимосвязи длины подземного междоузлия и балла устойчивости соломины при созревании овса подтвердили факт, что чем меньше длина подземного междоузлия в фазе 3 листьев, тем выше балл устойчивости стебля при созревании зерна овса в условиях как в засушливые годы, так и увлажненный год Якутии. Коэффициент корреляции между длиной подземного междоузлия и баллом устойчивости у овса К-4880 менее сильная — 0,4, а у стандарта Покровский до 0,6. Перспективный сорт К-4880 обеспечивает ежегодную прочность стебля до 9 баллов согласно методическим рекомендациям и шкале ВИР, сформировав урожайность зерна за 3 года исследований от 14 до 52 ц/га, в среднем — 30,8 ц/га, что достоверно выше стандартного сорта в 1,12 раза или 112% к стандарту Покровский (26,7 ц/га).
Verbal list learning and memory profiles in HIV-infected adults, Alzheimer’s disease, and Parkinson’s disease: An evaluation of the “cortical hypothesis” of NeuroAIDS
Creators: name: Ciccarelli, Nicoletta
name: Limiti, Silio
name: Fabbiani, Massimiliano
name: Baldonero, Eleonora
name: Milanini, Benedetta
name: Lamonica, Silvia
name: Cauda, Roberto
name: Giambenedetto, Simona Di
name: Silveri, Maria Caterina
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: HIV+ population is getting older because of progress in treatments. Yet, there are concerns that Older HIV+ individuals (OHIV+) may be more vulnerable for developing a “cortical” dementia such as Alzheimer Disease (AD). Our aim was to explore the hypothesis that the cognitive deficit extends to ‘‘cortical’’ functions in OHIV+ by comparing serial position effects (SPE) in different groups of participants affected by “cortical” or “subcortical” damage. We enrolled a total of 122 subjects: 22 OHIV+ (≥60 years of age), 31 Younger HIV+ (YHIV+) (<60 years of age), 18 participants with AD, 23 subjects with Parkinson Disease (PD), and 28 healthy subjects. All subjects performed verbal learning tasks (VLT) to explore SPE. Factorial analysis of covariance showed a significant effect of “group” (p p p = 0.257) interaction. Compared with healthy subjects (p = 0.003), AD had the most severe reduction of Primacy, confirming a primary “encoding deficit,” while PD confirmed a “frontal pattern.” OHIV+ showed a memory profile similar to that of PD with a worsening of the cognitive performance in comparison with YHIV+. In conclusion, we did not confirm the “cortical” hypothesis in OHIV+, at least in terms of learning and memory functions.
НОВЫЙ ИСХОДНЫЙ МАТЕРИАЛ ДЛЯ СЕЛЕКЦИИ БЕЗНАРКОТИЧЕСКИХ СОРТОВ КОНОПЛИ ПОСЕВНОЙ
Creators: name: Серков Валериан Александрович
name: Климова Людмила Владимировна
name: Данилов Михаил Васильевич
name: Белоусов Роман Олегович
name: Александрова Милена Роландовна
name: Давыдова Ольга Константиновна
Publisher: name: Международный сельскохозяйственный журнал
Year: 2020
Subjects: конопля посевная
безнаркотический сорт
среднерусский экотип
южный экотип
гибридная комбинация
каннабиноиды
тетрагидроканнабинол
хозяйственно ценный признак

description: Представлены результаты четырехлетнего цикла научно-исследовательских работ по созданию нового исходного материала для селекции высокопродуктивных безнаркотических сортов однодомной конопли посевной среднерусского экотипа. Исследования проводили в полевых и лабораторных условиях на естественном агрофоне. Получены экспериментальные данные по биоморфометрическим и хозяйственно ценным признакам и свойствам растений новых гибридных комбинаций. Комплексная оценка комбинаций с учетом их устойчивости к биотическим и абиотическим стрессорам позволила получить перспективный исходный материал для последующих этапов селекционного процесса. Выделены гибридные комбинации для создания новых сортов однодомной конопли посевной среднерусского экотипа с содержанием тетрагидроканнабинола в растениях менее 0,1%, стабилизированные по признаку однодомности, обладающие высоким выходом общего/длинного волокна в стебле, высокой семенной продуктивностью и содержанием масла в семенах. Отобранные гибридные комбинации вовлечены в селекционный процесс.
ВЛИЯНИЕ ПРИЕМОВ ТЕХНОЛОГИИ ВОЗДЕЛЫВАНИЯ НА УРОЖАЙНОСТЬ И КАЧЕСТВО ЗЕРНА СОРТОВ ОЗИМОЙ ПШЕНИЦЫ В НИЖЕГОРОДСКОЙ ОБЛАСТИ
Creators: name: Петров Леонид Кириллович
name: Саков Александр Петрович
Publisher: name: Международный сельскохозяйственный журнал
Year: 2020
Subjects: озимая пшеница
урожайность
клейковина
белок
сорта
нормы высева
сроки посева.

description: Представлены результаты сравнительного изучения влияния сроков посева и норм высева семян на рост, развитие, формирование урожайности и качество зерна наиболее перспективных современных сортов озимой пшеницы впервые в условиях светло-серых лесных почв Нижегородской области. По результатам исследований установлено, что полевая всхожесть семян изменялась по вариантам опыта в среднем при 1 сроке сева от 65,3 до 88,1%, при 2 сроке — от 68,2 до 83,8%, при 3 сроке — от 45,1 до 76,3%. Условия перезимовки растений озимой пшеницы были в целом удовлетворительными и по срокам сева изменялись в пределах 6,59-8,46 балла, а в среднем этот показатель составлял 7,48 балла. Выявлено, что среди сроков сева по урожайности изучаемой культуры выделился в среднем за 2017-2019 гг. первый из трех сроков (26-27 августа), при этом урожайность составила по срокам сева 7,84, 5,21 и 4,22 т/га соответственно. При изучении норм высева семян выяснено, что в среднем урожайность изменялась незначительно и при норме высева 6,0 млн в.с. (всхожих семян) составляла 5,94 т/га, при 4,5 млн в.с. — 5,78 т/га, при 3,0 млн в.с. — 5,56 т/га. Отмечено, что среди сортов, наиболее адаптированных к условиям изучаемого региона, следует выделить Немчиновскую 57, Московскую 56, Московскую 82, средняя урожайность которых за данный период составляла соответственно 5,85, 6,30 и 6,13 т/га, что на 13,6, 22,1 и 18,8% выше стандартного сорта Московская 39. Показано, что при рассмотрении качественных показателей зерна установлено максимальное значение белка и клейковины у сорта Московская 40 — 17,1 и 29,5%, что на 9,6 и 8,9% выше, чем у стандартного сорта Московская 39. Индекс деформации клейковины (ИДК) изменялся по всем вариантам опыта в годы исследований умеренно — от 67,0 до 81,2 ед.
ОЦЕНКА ЭКОНОМИЧЕСКОМ ЭФФЕКТИВНОСТИ СИСТЕМЫ ПРИМЕНЕНИЯ МИНЕРАЛЬНЫХ УДОБРЕНИЙ ПРИ РАЗНЫХ МЕТОДАХ РАСЧЕТА ПОТРЕБНОСТИ
Creators: name: Аканова Наталья Ивановна
name: Винничек Любовь Борисовна
name: Жданов Василий Юрьевич
name: Визирская Мария Михайловна
name: Жданов Иван Юрьевич
Publisher: name: Международный сельскохозяйственный журнал
Year: 2020
Subjects: рентабельность сельскохозяйственного производства
система применения удобрений
минеральное питание
экономическая эффективность.

description: В статье приведены способы составления и оценки экономической эффективности систем применения удобрений, составленных на основе расчетов потребности в элементах питания на планируемую урожайность. Приведены примеры апробации этих данных в полевых опытах и коррекции системы применения удобрений на основе полученных результатов.
Analysis of isoflavones and coumestrol in soybean sprouts
Creators: name: Oshima, Ayaka
name: Mine, Wakana
name: Nakada, Mitsuhiko
name: Yanase, Emiko
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: Plant Biology

description: High-performance liquid chromatography analysis is used to examine the distribution of isoflavones in different parts of soybean sprouts. Between the seed leaf and hypocotyl, the ratio of isoflavones differs depending on the aglycone type. Glycitein exists predominantly in the hypocotyl. Three compounds isolated from 4-day-old seed coats were identified as coumestrol and its glycosides.
Aggressive extensive cardiac mass in an HIV-1-infected patient: should we go for comfort therapy?
Creators: name: Vervloet, Delphine MTF
name: Pauw, Michel De
name: Demulier, Laurent
name: Vercammen, Jan
name: Terryn, Wim
name: Steel, Eva
name: Vandekerckhove, Linos
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Cardiac masses are rare, the differential diagnosis includes infections with vegetations or abscesses, neoplasms, thrombi, and structural abnormalities. A pathology specimen is essential in therapeutic strategy planning for a cardiac mass, also if the primary imaging findings look dramatic at the start. Even in an inoperable setting, a life-saving therapy might be available. We report a case of a 49-year-old man, known with HIV-1, who was several times admitted with pericarditis. Now he was hospitalized with progressive lower limb edema, atrial fibrillation and detection of a giant cardiac mass in left and right atrium with infiltration of surrounding tissues. Given the extent and invasiveness of the mass, he was inoperable. Biopsy specimen was obtained and staging was performed by PET-CT scan. The diagnosis of stage IV Burkitt lymphoma with predominant extranodal cardiac involvement was withheld wherefore promptly aggressive therapy was started according to the GMALL B-NHL86 protocol. The therapy was downgraded to R-CHOP due to tolerance problems. He achieved a complete remission and during follow-up no relapse was detected.
Nitration is exclusive to defense-related PR-1, PR-3 and PR-5 proteins in tobacco leaves
Creators: name: Takahashi, Misa
name: Shigeto, Jun
name: Izumi, Shunsuke
name: Yoshizato, Katsutoshi
name: Morikawa, Hiromichi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology

description: Protein tyrosine nitration is an important post-translational modification. A variety of nitrated proteins are reported in Arabidopsis leaves and seedlings, sunflower hypocotyls, and pea roots. The identities of nitrated proteins are species-/organ-specific, and chloroplast proteins are most nitratable in leaves. However, precise mechanism is unclear. Here, we investigated nitroproteome in tobacco leaves following exposure to nitrogen dioxide. Proteins were extracted, electrophoresed and immunoblotted using an anti-3-nitrotyrosine antibody. Mass spectrometry and FASTA search identified for the first time an exclusive nitration of pathogenesis-related proteins, PR-1, PR-3 and PR-5, which are reportedly located in the apoplast or the vacuole. Furthermore, Tyr36 of thaumatin-like protein E2 was identfied as a nitration site. The underlying mechanism and physiological relevance are discussed.
Transgenic expression of Telomerase reverse transcriptase (Tert) improves cell proliferation of primary cells and enhances reprogramming efficiency into the induced pluripotent stem cell
Creators: name: Hidema, Shizu
name: Fukuda, Tomokazu
name: Date, Shiori
name: Tokitake, Yuko
name: Matsui, Yasuhisa
name: Sasaki, Hiroki
name: Nishimori, Katsuhiko
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Developmental Biology
subject: Cancer

description: The enzymatic activity of telomerase is important for the extension of the telomere repeat sequence and overcoming cellular senescence. We generated a conditional transgenic mouse line, carrying the telomerase reverse transcriptase (Tert) expression cassette, controlled by the Cre-loxP-mediated recombination. In our study, Cre recombinase expression efficiently activated Tert expression, resulting in its increased enzymatic activity, which extended the period of cellular proliferation until the keratinocytes entered senescence. This suggests that transgenic Tert expression is effective in enhancing primary cell proliferation. Notably, Tert expression increased colony formation of induced pluripotent stem (iPS) cells after the introduction of four reprogramming factors, Oct-4, klf4, SOX-2, and c-Myc into the transgenic fibroblasts. To the best of our knowledge, this is the first study to show that the transgenic Tert expression enhances reprogramming efficiency of iPS cells, which indicates a critical role for Tert in the reprogramming process. Transgenic expression of telomerase reverse transcriptase improves cell proliferation of primary cells and enhances reprogramming efficiency into the iPS cell.
Imidazo[1,2-a]pyridine-substituted coumarin as a selective ratiometric sensor for Cu2+ ion
Creators: name: Shaily
name: Kumar, Ajay
name: Ahmed, Naseem
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: 60506 Virology

description: A novel fluorescent chemosensor, (E)-7-(diethylamino)-3-((2-phenylimidazo[1,2-a]pyridin-3-ylimino)methyl)-2H-chromen-2-one 1a, has been synthesised and characterised. This chemosensor displayed an extreme selective fluorescence emission only with Cu2+ ion over all other metal ions examined. The Job’s plot experiment analysis suggested the binding ratio of the chemosensor 1a with Cu2+ was 1:1 metal-to-ligand ratio. The association constant for Cu2+ towards receptor 1a obtained from Benesi–Hildebrand plot was found to be 4.859 × 103 M−1 with a detection limit 4.6 × 10−8 M. Fluorescence enhancement caused by Cu2+ binding with chemosensor 1a attributed to combinational effect of intramolecular charge transfer and chelation-enhanced fluorescence occurred at pH 8.0.
"Slame mes données" : dialogues actifs entre récits scientifiques et récits citoyens
Creators: name: Bats, Raphaëlle, Cécile
name: Garnier, Mathilde
Publisher: name: Zenodo
Year: 2024

description: Conférence donnée à l'AISLF 2024, à Ottawa, Canada.

Projet ECODOC.
Entretien de Hala Hamid Alawi auprès de Ahmad Salim al-Mawajdeh à propos de la période ottomane et de la citadelle de Karak
Creators: name: al-Mawajdeh, Ahmad Salim
name: Hala Hamid Alawi (Enquêtrice)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Source: http://www.calames.abes.fr/pub/ms/FileId-3139
description: Coverage: Karak, Jordanie
title: 01_2279
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Syntheses and biological evaluation of phosphoryl-containing polyunsaturated fatty acid derivatives as hypolipidemic agents
Creators: name: Hua, Fang
name: Yiping, Zhang
name: Quanling, Xie
name: Xiaoyan, Huang
name: Zhuan, Hong
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: A series of novel compounds phosphoryl-containing polyunsaturated fatty acid derivatives n-(diisopropoxy-phosphonamide)-alkyl ester (2a–2o) have been synthesized and evaluated for lowering hypolipidemia activities. Amongst all the synthesized compounds, compound 2d, 2h, and 2m showed significant lowering of triglyceride (TG) by 47.37%, 45.88%, and 45.69%, respectively, in triton induced hyperlipidemic in mice. Furthermore, compound 2d showed potent antihyperlipidemic activity and was found to decrease the plasma total cholesterol levels (TC) by 53.3%, TG by 29.3%, in high-fat diet induced hyperlipidemic in mice.
title: Planning for community based tourism in remote areas
title: bird watching in Arfak Mountains West Papua
titleType: Subtitle
Creators: name: Harwood, Sharon
Publisher: name: Charles Darwin University
Year: 2010

description: The focus of academic planning literature is on urban and metropolitan areas. As a result there is a dearth of literature related to planning in the more remote regions. The purpose of this research is to create an analytical framework to make a coherent examination of the planning knowledge production process applied by a remotely located community that supplies a bird watching tourism product. This thesis examines the relationship between the three types of planning theory in the planning knowledge production process to describe how planning theory contributes to the practices applied in a remote locale. A mixed methods research strategy was developed to determine the characteristics that are inherent to a bird watching tourism product and those that differentiate the product within a product range. The quantitative results from 714 bird watchers and 51 Tour Operators indicated that the differentiating characteristics of bird watching tourism products are dependent upon the presence of pre development conditions such as governance structures and infrastructure. The qualitative analysis of the decision making process found that the case study community planned for tourism development in isolation to knowledge about tourist preferences and in its stead focused upon the visiting Tour Operators perceptions of market demand. The results suggest that planning knowledge production is not limited to quantifiable data to substantiate financially competitive development in a remote location. The case study community demonstrated that planning knowledge that sustains the development within the community locale can be internally produced and more credible than quantifiable data. The thesis concluded that the application of urban derived planning theory serves to reinforce a marginalised perspective of remoteness and that a place based conceptualisation of planning for development in remote areas that considers the unique qualities of the people and the environment is required.
Facile preparation of a three-coordinate copper(I) complex: Steric hindrance, supramolecular structure, optical property and TD-DFT study
Creators: name: Zhao, Yi
name: Chai, Wen-Xiang
name: Song, Li
name: Zhang, Yi-Cheng
name: Shi, Hong-Sheng
name: Tao, Xiao-Dong
name: Kang-Ying Shu
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: The solution reaction of Cu(CH3CN)4(PF6) with a NN ligand 2-(2′-quinolyl)benzimidazole and a sterically bulky P ligand tris(2-methylphenyl)phosphine facilely yielded the three-coordinate copper(I) complex [Cu(2-QBI)(o-Tol3P)](PF6) (1). The complex has been characterized by single-crystal X-ray diffraction, Fourier Transform infrared spectroscopy and elemental analysis, UV–Vis (ultraviolet–visible) and photoluminescent spectroscopy studies. Time-dependent density functional theory has been used for calculating the electronic origin of the low-lying excited states, which were unexpectedly assigned mainly as a ligand-to-ligand or an intra-ligand charge transfer state instead of the metal-to-ligand charge transfer transition. Interestingly, 1 exhibits a concentration-dependent absorption in solution. This absorption behavior is interpreted as some excimer's formation based on the study of supramolecular structure, spectroscopy and calculations.
The acoustic repertoire of lycaenid butterfly larvae
Creators: name: Riva, Federico
name: Barbero, Francesca
name: Bonelli, Simona
name: Balletto, Emilio
name: Casacci, Luca P.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology

description: Sounds and vibrations play vital roles in intra- and inter-specific communication of many insect taxa, for sexual display, defence and social recruitment. In Lepidoptera, sound production occurs in larvae, pupae and adults and has evolved in response to selection of sexual or defensive traits. About 75% of the 6000 estimated lycaenid butterflies are associated with ants (termed “myrmecophilous species”) and many species produce acoustic emissions during pre-imaginal development. It was initially believed that these acoustic emissions were only produced by myrmecophilous species, but later studies showed that the ability to produce sounds may be universal among this butterfly family. The acoustic repertoire of the late-instar larvae of 12 lycaenid species (Polyommatinae and Lycaeninae), showing different degrees of interaction with ants, was analysed by investigating 12 acoustic parameters measured on the call fundamental unit (pulse). All samples produced species-specific calls whose spectra were characterized by harmonic frequency components. The inter-specific call diversity better reflects the level of association with ants than the taxonomic relationships between species. Our results support the hypothesis that the ability to emit acoustic signals is widespread in lycaenids, and that these emissions play a role in myrmecophilous interactions.
Teacher use of indigenously developed curriculum materials
Creators: name: Norman, Pamela
Publisher: name: Charles Darwin University
Year: 1998

description: As leaders in Aboriginal education strive to develop appropriate curriculum materials for Aboriginal schools and to support their successful implementation, lessons can be learned from this research. The study centred on investigating teachers' opinions and use of a set of curriculum materials which had been developed in school-based writing workshops. Seventy-six Aboriginal teachers were involved in these workshops. Data provided illumination of teachers' opinions not only of the materials, but also about how the materials writing project was organised and the materials were developed. Three conceptual frameworks informed the research design. The organisation, development and application phases of Print’s (1993) model of the curriculum process provided an overarching framework. The Concerns-Based Adoption Model provided the concepts of 'stages of concern', 'levels of use', 'innovation configurations' and 'interventions' which were so useful for investigating the implementation of the resource. The grounded theory approach was used in the analysis of qualitative data. Subjects were teachers in Northern Territory Aboriginal schools and data-gathering instruments included a questionnaire, an interview and a checklist. The results showed that the resource had been widely adopted and had had a profound effect on the way English was taught in Northern Territory Aboriginal schools. With the exception of the methodology which was intended to lead to students writing independently in English, all the critical components of the resource had been successfully implemented. Important qualities of the resource were its reader friendliness, user-friendliness, models of work and use of topics of relevance to Aboriginal sociocultural contexts. The study identified issues and exemplary practices during the three phases of the curriculum process. Derived from the findings a grounded theory is presented for developing and implementing curriculum materials for Aboriginal schools. Recommendations include the need for improved training of change facilitators to support the implementation process and further research into effective teaching-learning models.
Rising Times at Southernmost Brittania [16½h / 51;30°] - Ptolemy's Almagest by Toomer (Gerald J.) (1984) | Type-B (ID n° 333)
Creators: name: Toomer, Gerald J.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Astronomy
Medieval history

description: This is a type B edition: A type-B edition corresponds to a critical edition of several table witnesses:
 it is based on several different editions, themselves based on tables from different primary sources.
 A type-B edition can be based on type-A, type-B or type-C editions.
You can find it on the DISHAS project website from this link: https://dishas.obspm.fr/table-edition/333
description: Source: Ptolemy's Almagest, Toomer (Gerald J.), 1984
Ethylenedioxythiophene as a novel central unit for bent-core liquid crystals
Creators: name: Ashwath Narayana Gowda
name: Kumar, Sandeep
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Plant Biology

description: We have discovered that ethylenedioxythiophene (EDOT) can be used as a central unit for the synthesis of bent-core liquid crystals (BC LCs). Two series of EDOT-based BC LCs are prepared via Sonogashira coupling reaction. The mesophase behaviour of all the compounds was characterised using a combination of polarising optical microscopy, differential scanning calorimetry and X-ray diffraction measurements. EDOT-based three-ring compounds were found to be nonliquid crystalline, while all the four derivatives of five-ring series, including a branched alkoxy chain derivative, display enantiotropic nematic phase over wide temperature range. The bent angle of these compounds is about 153°, which falls in between typical rod-like and banana liquid crystals. The transition temperature of branched alkoxy chain compound is lower than straight alkoxy chain compounds. The detailed XRD investigations of all the mesogens corroborate the presence of nematic phase.
Grey analytic hierarchy process applied to effectiveness evaluation for groundwater potential zone delineation
Creators: name: Satiprasad Sahoo
name: Anirban Dhar
name: Amlanjyoti Kar
name: Prahlad Ram
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Cell Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: An attempt has been made to identify plausible groundwater potential zones (GWPZ) based on Grey Analytic Hierarchy Process Method (Grey-AHP) using integrated remote sensing and geographic information system. Grey-AHP combines the advantages of classical analytic hierarchy process and grey clustering method for accurate estimation of weight coefficients. The method also examines the effectiveness of GWPZ identification process. The proposed methodology has been applied to the Hirakud canal command area, Odisha (India). Feature layers [e.g. soil type, geology] are utilized for groundwater potential index (GWPI) calculation. The resulting GWPI map has been classified into three GWPZ namely: good, moderate and poor. Effectiveness based on grey clustering method is found to be in between ‘better’ and ‘common’ classes. Value of coefficient of determination (R2 = 0.865) supports the obtained effectiveness evaluation result. This analysis demonstrates the potential applicability of the methodology for a general aquifer system.
Synthesis, liquid crystalline mesophases and morphologies of diblock copolymers composed of a poly(dimethylsiloxane) block and a nematic liquid crystalline block
Creators: name: Renbo Wei
name: Jinyi Ma
name: Hongxing Zhang
name: Yaning He
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine

description: In this study, a series of liquid crystalline diblock copolymers, composed of a soft poly(dimethylsiloxane) (PDMS) block with a deﬁned length and a side-on liquid crystalline poly(3ʹʹ-acryloyloxypropyl 2,5-di(4ʹ-butyloxybenzoyloxy) benzoate) (P3ADBB) block with different lengths, are synthesised by the atom transfer radical polymerisation. The macromolecular structures, liquid crystalline properties and the microphase-separated morphologies of the diblock copolymer are investigated by 1H NMR, FT-IR, GPC, POM, DSC and TEM. The results show that the well-deﬁned diblock copolymers (PDMSn-b-P3ADBBm) possess four different soft/rigid ratios (n = 58, m = 10, 25, 42, 66) and relatively narrow molecular distributions (PDI ≤ 1.30). P3ADBB blocks of the copolymers show nematic sub-phases, which are identical to the mesomorphic behaviour of the homopolymer P3ADBB. After being annealed at 90°C in a vacuum oven for 48 h, the copolymers form a lamellar morphology when m = 10 and morphologies of PDMS spheres embedded in P3ADBB matrix when m = 25, 42 and 66.
Ultrasound accelerated sulfonylation of amines by p-acetamidobenzenesulfonyl chloride using Mg–Al hydrotalcite as an efficient green base catalyst
Creators: name: Truong, Binh Nhat
name: Le, Luong Huu
name: Duy-Khiem Nguyen Chau
name: Duus, Fritz
name: Luu, Thi Xuan Thi
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: The sulfonylation reaction of various aliphatic, alicyclic, aromatic, and hetero-aromatic amines with p-acetamidobenzenesulfonyl chloride has been investigated using different types of base catalysis under varied reaction conditions. Mg–Al hydrotalcite, characterizable as an inexpensive, reusable, and green solid catalyst, was found to be the most efficient catalyst, when the reaction is carried out in a minimum volume of solvent (acetone). The reaction was found to be accelerated drastically with the support of ultrasound irradiation, affording the sulfonamides in yields better or equivalent to those obtained under the longer lasting conventional stirring conditions.
API-based two-dimensional dispatching decision-making approach for semiconductor wafer fabrication with operation due date–related objectives
Creators: name: Li, You
name: Zhibin Jiang
name: Wenyou Jia
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: This paper presents an adjacent pairwise interchanges (API)-based two-dimensional dispatching decision-making approach for semiconductor wafer fabrication with operation due date-related objectives. Each time when a machine becomes idle, the proposed dispatcher chooses a target processing job from the competing jobs and assigns it a start time. Giving the operation due date information of each competing job, we formulate this dispatcher as the mean absolute deviation problem to keep the jobs finished around their operation due dates in a proactive way. Dominance properties of this problem are established using proof by APIs. Then, a heuristic comprised of job selection within candidate set, movement of job cluster and local search is designed to solve this problem more efficiently. Numerical experiments validate the efficiency of the proposed heuristic in a single-machine environment as well as in a simulated wafer fab abstracted from practice. In comparison with four most referenced due date-related dispatching rules, the simulation study reveals the benefits brought by the two-dimensional dispatching decision with different due date tightness taken into account.