cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anatomy and biomechanics of the PIA-Arachnoid complex
Creators: name: Scott, Gregory George
Publisher: name: University of Utah
Year: 2014
Subjects: Arachnoid
Finite elements
Magnetic resonance imaging
Meninges
Optical coherence tomography
Traumatic brain injury

description: Traumatic brain injury (TBI) is a leading cause of death and disability in the U.S.A. In mild cases, common etiologies of TBI (i.e., hemorrhage or edema) are not readily apparent during medical examination. We propose that the pia-arachnoid complex (PAC) contributes to the brain's response in TBI. The PAC is the only layer of tissue between the brain and dura (a tough membrane tightly adhered to the skull), and acts as a mechanical tether between the brain and skull. If the fine structures of the PAC are damaged during TBI, they likely go undiagnosed due to their small size and difficulty to image. To better understand the mechanics of PAC injury, several experimental and computational studies were conducted. First, a novel application of optical coherence tomography (OCT) was utilized to acquire microscale images of the in-situ porcine PAC and measure the amount of arachnoid trabeculae (AT) present. Next, two parametric studies were conducted on a microscale model of the PAC which evaluated its sensitivity to variable substructure moduli and AT volume fraction (VF). Afterwards, the microscale PAC model was paired with a macroscale head model to determine the effect of a nonuniform AT VF on whole-head mechanics. Finally, an immature porcine model of mild TBI was used to investigate PAC damage following head rotation, and identify clinically relevant MRI biomarkers indicative of PAC damage. The OCT imaging of the PAC revealed high variability of VF within each head, but low variability between brain regions and between animals. The microscale parametric studies showed high sensitivity to changes in substructure moduli and VF. The macroscale model studies showed improvement of intracranial hemorrhage prediction when variable VF was introduced into the models. Clinically relevant biomarkers of PAC damage were not able to be confidently developed, but increased sample size and improved resolution may lead to innovative biomarkers for TBI. The work presented here addresses a significant lack of data on the PAC, and presents new insights into its anatomy and biomechanics. Many of the studies presented here are the first of their kind, opening up many new paths of TBI research opportunities.
Chemical composition, cytotoxicity and molecular profiling of Cordia africana Lam. on human breast cancer cell line
Creators: name: Ashmawy, Abeer M.
name: Ayoub, Iriny M.
name: Eldahshan, Omayma A.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Metabolic profiling of the hexane extract and essential oil of Cordia africana Lam., an economically important agroforestry species, was performed using GC-FID and GC-MS. Cytotoxicity was assessed in MCF-7 cancer cells using sulphorhodamine-B assay. Caspase-8, BcL-2 and Ki-67 levels were evaluated using enzyme-linked immunosorbent assay. Forty-one compounds were identified in the hexane extract, meanwhile, eighty compounds were annotated in the essential oil. n-Decane (9.52%), β-sitosterol (8.13%), undecane (6.32%) and palmitaldehyde (5.50 %) were the major compounds identified in the hexane extract, whereas, β-caryophyllene (32.0%), germacrene D (10.12%) and δ-cadinene (7.20%) predominated in the essential oil. The half maximal inhibitory concentrations (IC50) of the extract and oil were 4.55 µg/mL and 12.90 µg/mL, respectively. Caspase-8 activity increased significantly in hexane extract treated cells. Furthermore, BcL-2 and Ki-67 protein expression levels were significantly decreased. Cordia africana Lam exhibit potent cytotoxicity against breast cancer cell line, most likely through apoptosis regulation.
Sonnenfleckenzeichnung Nr. 22627.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 03.10.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Sonnenfleckenzeichnung Nr. 22664.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.11.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Fine-scale radar observations of orographic precipitation features during a Wasatch Mountain winter storm
Creators: name: Campbell, Leah Suzanne
Publisher: name: University of Utah
Year: 2014
Subjects: Fine-scale precipitation
Orographic
Radar
Wasatch

description: Fine-scale spatiotemporal variations in orographic precipitation pose a major challenge for weather prediction in mountainous regions. Here we use ground-based X-band radar observations collected during IOP6 of the Storm Chasing Utah Style Study (SCHUSS) to provide an illustrative example of such variations during a cold-frontal passage over the Wasatch Mountains of northern Utah. Emphasis is placed on precipitation features in and around Little Cottonwood Canyon (LCC), which cuts orthogonally eastward into the Wasatch Mountains. This work also demonstrates the potential for improving weather analysis and forecasting of such variations in LCC using a gap-filling radar.  Precipitation during the weakly stratified prefrontal storm stage of IOP6 featured a wave-like barrier-scale reflectivity maximum along the Wasatch Crest that extended weakly westward and upstream over the transverse ridges flanking LCC. These characteristics appeared to reflect a veering wind profile, which produced southwesterly flow over the ridges flanking LCC but cross-barrier westerly flow further aloft. Sublimation within dry subcloud air further diminished radar reflectivities over lower LCC. The cold front was associated with stronger reflectivities over lower LCC and at lower-to-mid elevations along the northwest-facing canyon wall, consistent with shallow, northwesterly upslope flow. Eventually, shallow precipitating cells developed in the moist-neutral postfrontal flow, with the depth, coverage and intensity of these cells increasing from over the Salt Lake Valley to upper LCC.
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.11.1967, erstellt von Dendis am Skalnate Pleso Observatorium
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage am Skalnate Pleso Observatorium. Es sind zudem statistische Angaben für die Bestimmung der Fleckenrelativzahl notiert. Instrument: unbekannt, Sonnenbild D = 25 cm
Coupling a land-surface model to large-eddy simulation to study the nocturnal boundary layer
Creators: name: Shingleton, Nick
Publisher: name: University of Utah
Year: 2012
Subjects: Land-surface model
Large-eddy simulation
Nocturnal
Stable

description: Negatively buoyant forces in the stable boundary layer (SBL) damp turbulent motions, resulting in decreased transport of momentum, heat and water vapor. During  high levels of stratification this can cause intermittent turbulence, gravity waves and weak turbulent fluxes. In some cases, decoupling between the atmospheric boundary layer (ABL) and land-atmosphere fluxes can occur. Accurately reproducing these phenomena requires detailed treatment of the physical processes that govern the two-way dynamic interaction between surface properties and the ABL. Increasingly, large-eddy simulation (LES) is used to study land-atmosphere interactions in the SBL. In these studies, the dominant treatment of surface boundary conditions is to  specify a known state or flux. This research uses LES that is fully coupled to a land-surface model (LSM) to investigate the SBL. The LSM explicitly solves for the  transport of heat and water in a one-dimensional column of the upper soil. Coupling to the atmosphere is achieved through a surface budget, which partitions the available  radiative forcing into ground heat flux and sensible and latent heat fluxes. Turbulent boundary layer profiles and surface fluxes are compared to field data and results from simulations of the GABLS3 LES intercomparison case.
Additional file 1 of Prognostic impact of pretreatment T790M mutation on outcomes for patients with resected, EGFR-mutated, non-small cell lung cancer
Creators: name: Matsumoto, Yoshiya
name: Kawaguchi, Tomoya
name: Watanabe, Masaru
name: Isa, Shun-ichi
name: Ando, Masahiko
name: Tamiya, Akihiro
name: Kubo, Akihito
name: Kitagawa, Chiyoe
name: Yoshimoto, Naoki
name: Koh, Yasuhiro
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1.
Secondary metabolites of Curvularia sp. G6-32, an endophyte of Sapindus saponaria, with antioxidant and anticholinesterasic properties
Creators: name: Polli, Andressa Domingos
name: dos Santos Ribeiro, Marcos Alessandro
name: Garcia, Adriana
name: Polonio, Julio Cesar
name: Santos, Caroline Menicoze
name: Silva, Angela Aparecida
name: Orlandelli, Ravely Casarotti
name: Castro, Juliana Cristina
name: Abreu-Filho, Benício Alves
name: Cabral, Marcia Regina Pereira
name: Sarragiotto, Maria Helena
name: Pamphile, João Alencar
name: Azevedo, João Lúcio
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: In the present study, the biological activity of an extract of the secondary metabolites (E-G6-32) produced by the Curvularia sp. G6-32 endophyte (isolated from the medicinal plant Sapindus saponaria L.) was investigated. The antioxidant potential was confirmed by the DPPH (22.5%) and ABTS (62.7%) assays, and the total phenolic compound content was 40 µg gallic acid equivalents/mg. The extract E-G6-32 displayed good inhibitory activity toward butyrylcholinesterase (BuChE; IC50 = 110 ± 0.05 µg mL−1). The extract E-G6-32 was subjected to spectroscopic and mass spectrometry analyses. Comparison with the literature data confirmed that (-)-asperpentyn (1) was a major component. Asperpentyn belongs to the epoxyquinone family, which has attractive structural complexity, diverse functional groups, and a broad range of biological activities, including specific enzyme inhibitory activity. Our results suggest that Curvularia sp. G6-32 is a promising source of bioactive secondary metabolites and contains (-)-asperpentyn, which has potential pharmaceutical interest.
Radial basis function-based numerical methods for the simulation of platelet aggregation
Creators: name: Shankar, Varun
Publisher: name: University of Utah
Year: 2014
Subjects: Forcing method
Immersed boundary method
Meshfree methods
Platelet aggregation
Radial basis Functions (RBFs)

description: Platelet aggregation, an important part of the development of blood clots, is a complex process involving both mechanical interaction between platelets and blood, and chemical transport on and o the surfaces of those platelets. Radial Basis Function (RBF) interpolation is a meshfree method for the interpolation of multidimensional scattered data, and therefore well-suited for the development of meshfree numerical methods. This dissertation explores the use of RBF interpolation for the simulation of both the chemistry and mechanics of platelet aggregation. We rst develop a parametric RBF representation for closed platelet surfaces represented by scattered nodes in both two and three dimensions. We compare this new RBF model to Fourier models in terms of computational cost and errors in shape representation. We then augment the Immersed Boundary (IB) method, a method for  uid-structure interaction, with our RBF geometric model. We apply the resultant method to a simulation of platelet aggregation, and present comparisons against the traditional IB method. We next consider a two-dimensional problem where platelets are suspended in a stationary fluid, with chemical diusion in the fluid and chemical reaction-diusion on platelet surfaces. To tackle the latter, we propose a new method based on RBF-generated nite dierences (RBF-FD) for solving partial dierential equations (PDEs) on surfaces embedded in 2D domains. To robustly tackle the former, we remove a limitation of the Augmented Forcing method (AFM), a method for solving PDEs on domains containing curved objects, using RBF-based symmetric Hermite interpolation. Next, we extend our RBF-FD method to the numerical solution of PDEs on surfaces embedded in 3D domains, proposing a new method of stabilizing RBF-FD discretizations on surfaces. We perform convergence studies and present applications motivated by biology. We conclude with a summary of the thesis research and present an overview of future research directions, including spectrally-accurate projection methods, an extension of the Regularized Stokeslet method, RBF-FD for variable-coecient diusion, and boundary conditions for RBF-FD.
Sonnenfleckenzeichnung Nr. 22638.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.10.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
A new diterpene and other compounds from the unripe female cones of Wollemia nobilis
Creators: name: Venditti, Alessandro
name: Frezza, Claudio
name: Rossi, Giacomo
name: Sciubba, Fabio
name: Ornano, Luigi
name: De Vita, Daniela
name: Toniolo, Chiara
name: Tomassini, Lamberto
name: Foddai, Sebastiano
name: Nicoletti, Marcello
name: Di Cocco, Maria Enrica
name: Bianco, Armandodoriano
name: Serafini, Mauro
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: In this work, the first phytochemical analysis ever performed on the unripe female cones of Wollemia nobilis W. G. Jones, K. D. Hill & J. M. Allen was described. The analysis evidenced the presence of a new derivative of sandaracopimaric acid together with rare diterpenoid derivatives and known compounds of chemosystematic and bioactivity relevance. Some of these were evidenced in the species or in the family for the first time during this study. The further implications of the isolated compounds in the field of chemosystematics, pharmacology and nutraceutics were discussed.
Effect of cut on secondary metabolite profile in hydroponically-grown Rumex acetosa L. seedlings: a metabolomic approach
Creators: name: Ceccanti, Costanza
name: Landi, Marco
name: Rocchetti, Gabriele
name: Moreno, M. Begoña Miras
name: Lucini, Luigi
name: Incrocci, Luca
name: Pardossi, Alberto
name: Guidi, Lucia
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: Computational Biology

description: Seedlings of Rumex acetosa L. (sorrel) were grown in floating system and two consecutive cuts took place: 15 (C1) and 30 (C2) days after sowing. An untargeted metabolomics approach was utilised to fingerprint phenolics and other health-related compounds in sorrel leaves, as well as to unveil differences between the two cuts. The untargeted approach allowed to putatively identify 458 metabolites considering both the cuts. Three new terpenoids and two new phenylpropanoid glycosides (dihydrosyringin and dihydroconiferin) with antifungal and anti-inflammatory activity were annotated. Overall, leaves from C2 had lower level of secondary metabolites (44 were down-accumulated), especially sesquiterpenes and stilbenes. Conversely, anthocyanins showed a relevant increase in C2 than in C1 leaves. The dataset suggests that sorrel leaves represent a good source of nutraceutical compounds and unveils the pivotal effect of pre-harvest factor in secondary metabolite profile.
Sonnenfleckenzeichnung Nr. 22609.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 12.09.1967, erstellt von Antoine Zelenka
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Sonnenfleckenzeichnung Nr. 22631.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 07.10.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Additional file 1 of Identifying metabolic syndrome in migrant Asian Indian adults with anthropometric and visceral fat action points
Creators: name: Sluyter, John D.
name: Plank, Lindsay D.
name: Rush, Elaine C.
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1: Text S1. Measurement of mass in a single pixel. Text S2. Calculation of abdominal fat variables. Table S1. Percent explained variance (R2; %) for models of adjusted associations between abdominal fat variables and metabolic risk factors. Table S2. Standardized regression coefficients for associations between abdominal fat variables and cardiometabolic risk factors, adjusted for sex and age. Table S3. Discrimination performance of parameters to detect metabolic risk factors other than waist circumference. Table S4. Diagnostic and predictive values of parameters to detect ≥2 metabolic risk factors (IDF criteria for MetS) other than waist circumference in males. Table S5. Diagnostic and predictive values of parameters to detect ≥ 2 metabolic risk factors (IDF criteria for MetS) other than waist circumference in females.
Examining the geographic dimensions of risk perception, communication, and response during the evacuation and return-entry process
Creators: name: Siebeneck, Laura Kathryn
Publisher: name: University of Utah
Year: 2012
Subjects: Cedar rapids
Evacuation
Flood
Hazards
Return-entry

description: The focus of this research is the geographical and temporal dimensions of the evacuation and return-entry process (EREP). The return-entry process, or the movement of evacuees back home after issuance of an all-clear message, presents unique hazards especially in cases where an area has sustained damage. The goal of this study is to advance our understanding of how risk  perception, risk communication, and geographic and demographic factors influence evacuee behavior across the EREP. The four research objectives for this study are as follows: (1) Develop a typology of return-entry strategies and identify the factors that are most salient in  making all-clear decisions by emergency managers, (2) Examine how evacuees risk perception varies geographically and temporally throughout the EREP, (3) Examine how risk communication varies geographically and temporally throughout the EREP, and (4) Determine  what factors influence compliance with return orders.
Treatment time reduction through parameter optimization in magnetic resonance guided high intensity focused ultrasound treatments
Creators: name: Coon, Joshua
Publisher: name: University of Utah
Year: 2013
Subjects: Cancer
MRIgHIFU
Optimization
Ultrasound

description: Magnetic Resonance guided High Intensity Focused Ultrasound (MRgHIFU) treatments are a promising modality for cancer treatments in which a focused beam of ultrasound energy is used to kill tumor tissue. However, obstacles still exist to its widespread clinical implementation, including long treatment times. This research demonstrates reductions in treatment times through intelligent selection of the usercontrollable parameters, including: the focal zone treatment path, focal zone size, focal zone spacing, and whether to treat one or several focal zone locations at any given time. Several treatments using various combinations of these parameters were simulated using a finite difference method to solve the Pennes bio-heat transfer equation for an ultrasonically heated tissue region with a wide range of acoustic, thermal, geometric, and tumor properties. The total treatment time was iteratively optimized using either a heuristic method or routines included in the Matlab software package, with constraints imposed for patient safety and treatment efficacy. The results demonstrate that large reductions in treatment time are possible through the intelligent selection of user-controllable treatment parameters. For the treatment path, treatment times are reduced by as much as an order of magnitude if the focal zones are arranged into stacks along the axial direction and a middle-front-back ordering is followed. For situations where normal tissue heating constraints are less stringent, these focal zones should have high levels of adjacency to further decrease treatment times; however, adjacency should be reduced in some cases where normal tissue constraints are more stringent. Also, the use of smaller, more concentrated focal zones produces shorter treatment times than larger, more diluted focal zones, a result verified in an agar phantom model. Further, focal zones should be packed using only a small amount of overlap in the axial direction and with a small gap in the transverse direction. These studies suggest that all treatment time reductions occur due to selection of parameters that advantageously use mechanisms of decreasing the focal zone size to concentrate the power density, increasing thermal superposition in the tumor, decreasing thermal superposition in the normal tissue, and advantageously using nonlinear rates of thermal dose deposition with increasing temperature.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.11.1967, als Blatt eröffnet dank auswärtiger Beobachtungen, ausgewertet in Zürich, beschriftet von der Hand von Max Waldmeier mit: Kopie Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung bzw. Auswertung aufgrund auswärtiger Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen direkt auf dem Vordruck, erstellt durch Mitarbeitende der Eidgenössischen Sternwarte Zürich
Sonnenfleckenzeichnung Nr. 22598.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.08.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Performing the document in Francis Alys's re-enactments (2001)
Creators: name: Lyver Harris, Emily Rose
Publisher: name: University of Utah
Year: 2014
Subjects: Francis Alys
Mexico City
Re-enactments

description: In Francis Alÿs's two-channel video Re-enactments, the artist is filmed as he walks through the streets of downtown Mexico City with a loaded gun in his hand until he is arrested. Managing to avoid charges, Alÿs repeats the same series of events, replicating the performance based on the footage captured by his collaborator, artist Rafael Ortega. "Real" and "Re-enactment," the two videos that comprise Re-enactments, juxtapose the footage of these two performances, taking two divergent approaches to filming the event. In Re-enactments, the performance and the documentation are thoroughly interwoven and mutually dependent; the footage of the initial performance shapes its recreation, which likewise produces another video. In this thesis, I consider Re-enactments both as a live performance that is responsive to and contingent on its setting in Mexico City's downtown, or Centro, and as a video performance that carefully constructs the scene for the viewer. I argue that this work challenges the conventional relationship between performance and its documentation with video by embedding the documentation into the structure of the work. While the current scholarship on this work disregards its documentation as a formative element in the work, I show how the video documents in Re-enactments do not merely refer back to the live performance, but rather act as a crucial counterpart to it. Additionally, by situating Re-enactments in the context of Mexico City at the turn of the twentieth century, I show how this work responds to its environment as well to widely circulated media representations about the city. In rehearsing an act of crime that is then circulated internationally, Re-enactments both generates and critically responds to stereotypes of Mexico City as a center of violence and corruption. While Re-enactments draws on clichés of violence in Mexico City, the videos also attest to how such images are constructed, deliberately highlighting the ways in which the footage has been manipulated. Rather than acting as records of the events of the performance, the videos that comprise Re-enactments demonstrate the performative qualities of documentation.
Sonnenfleckenzeichnung Nr. 22679.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.12.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Radio frequency sensing measurements and methods for location classification in wireless networks
Creators: name: Maas, Dustin C.
Publisher: name: University of Utah
Year: 2014
Subjects: Localization
Radio tomography
Signal processing

description: The wireless radio channel is typically thought of as a means to move information from transmitter to receiver, but the radio channel can also be used to detect changes in the environment of the radio link. This dissertation is focused on the measurements we can make at the physical layer of wireless networks, and how we can use those measurements to obtain information about the locations of transceivers and people. The first contribution of this work is the development and testing of an open source, 802.11b sounder and receiver, which is capable of decoding packets and using them to estimate the channel impulse response (CIR) of a radio link at a fraction of the cost of traditional channel sounders. This receiver improves on previous implementations by performing optimized matched filtering on the field-programmable gate array (FPGA) of the Universal Software Radio Peripheral (USRP), allowing it to operate at full bandwidth. The second contribution of this work is an extensive experimental evaluation of a technology called location distinction, i.e., the ability to identify changes in radio transceiver position, via CIR measurements. Previous location distinction work has focused on single-input single-output (SISO) radio links. We extend this work to the context of multiple-input multiple-output (MIMO) radio links, and study system design trade-offs which affect the performance of MIMO location distinction. The third contribution of this work introduces the "exploiting radio windows" (ERW) attack, in which an attacker outside of a building surreptitiously uses the transmissions of an otherwise secure wireless network inside of the building to infer location information about people inside the building. This is possible because of the relative transparency of external walls to radio transmissions. The final contribution of this dissertation is a feasibility study for building a rapidly deployable radio tomographic (RTI) imaging system for special operations forces (SOF). We show that it is possible to obtain valuable tracking information using as few as 10 radios over a single floor of a typical suburban home, even without precise radio location measurements.
Sonnenfleckenzeichnung Nr. 22665.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.11.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
The proposed structures of phenolic compounds isolated from Piper betle L. differ from those of the compounds obtained by total synthesis
Creators: name: Noshita, Toshiro
name: Sato, Tatsuya
name: Iwayama, Takahito
name: Yamada, Yohei
name: Ouchi, Hidekazu
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: We describe the syntheses of phenolic compounds, 4-[(1E, 3E, 5E)−6-(4-octyloxyphenyl)hexa-1,3,5-trien-1-yl]benzene-1,2-diol (1) and 3-(n-dodecyloxy) phenol (2), isolated from Piper betle. The triene moiety of 4-[(1E, 3E, 5E)−6-(4-octyloxyphenyl)hexa-1,3,5-trien-1-yl]benzene-1,2-diol was formed via two different methods, the Horner–Wadsworth–Emmons reaction and the McMurry coupling reaction. The spectral data of synthesized compounds show differences with those of reported as the naturally occurring compounds.
Sonnenfleckenzeichnung Nr. 22685.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 25.12.1967, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Combustion and pollutant formation in the overthrow region of spreader stokers
Creators: name: Purcell, Steven Patrick
Publisher: name: University of Utah
Year: 2012
Subjects: Mechanical Stokers
Pulverized Coal

description: A considerable amount of research has been performed  on pulverized coal in recent years. There are, however, a  number of alternatives to direct combustion of a powdered coal. One method which has become popular is the coal stoker. In stoker combustion relatively large particles (up to 1.5 inches in diameter) are burned, primarily in large flat beds. The purpose of this work was to examine the combustion and pollutant formation characteristics of a single type of coal stoker: the spreader stoker.  Specifically, the overthrow or feed region of the spreader  stoker was studied. The experimental portion of the study  consisted of the injection of various sizes of coal into a  vertical tube furnace designed to simulate the environment within a spreader stoker. Experimental results were in the form of the flue gas composition measurements, which were subsequently converted to burn rate, and nitrogen conversion (to NO). It was found that particles greater than 0.10 inch undergo very little combustion in the overthrow region. Further, of the particles which did react (less than 0.10 inch), a relatively high nitrogen conversion of 35%-40% was noted. The process was modelled mathematically by a system of three transient, coupled second-order partial differential equations. The results (predictions) of the model were consistent with experimental observations with respect to burn rate - particle size functionality. No attempt was made to model the gas phase kinetics of NO formation.
Sonnenfleckenzeichnung Nr. 22646.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.10.1967, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Additional file 1 of The effect of nicotine-containing products and fetal sex on placenta-associated circulating midpregnancy biomarkers
Creators: name: Sundet, Birgitte Kordt
name: Kreyberg, Ina
name: Staff, Anne Cathrine
name: Carlsen, Karin Cecilie Lødrup
name: Bains, Karen Eline Stensby
name: Berg, Jens Petter
name: Granum, Berit
name: Haugen, Guttorm
name: Hedlin, Gunilla
name: Jonassen, Christine Monceyron
name: Nordhagen, Live Solveig
name: Nordlund, Björn
name: Rehbinder, Eva Maria
name: Rudi, Knut
name: Rueegg, Corina Silvia
name: Sjøborg, Katrine Dønvold
name: Skjerven, Håvard Ove
name: Söderhäll, Cilla
name: Vettukattil, Riyas
name: Sugulle, Meryam
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: Table S1. Nicotine exposure by fetal sex and midpregnancy maternal biomarker concentrations for the Nicotine exposure study group (n = 2278).
A new sesquiterpenoid and further natural products from Taraxacum portentosum Kirschner & Štěpánek, an endangered species
Creators: name: Michalska, Klaudia
name: Marciniuk, Jolanta
name: Stojakowska, Anna
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: Plant Biology

description: The chemical studies of roots and aerial parts of Taraxacum portentosum Kirschner & Štěpánek, a member of the section Palustria (H. Lindb.) Dahlst. (Asteraceae), led to the isolation of one new eudesmanolide and 13 known compounds, including five sesquiterpenoids: taraxinic acid, 11β,13-dihydrotaraxinic acid, taraxinic acid β-glucopyranosyl ester and its 11β,13-dihydroderivative, ixerin D, one apocarotenoid ‒ loliolide and seven phenolics: scopoletin, 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone, methyl p-hydroxyphenylacetate, 5-methoxy-eugenyl-4-O-β-glucopyranoside, syringin, dihydroconiferin, and dihydrosyringin. Their structures were established by 1H NMR. The new compound was characterized as 3-oxo-4βH-11,13-eudesmen-12,6-olide-8-O-β-glucopyranoside based on spectroscopic data (1 D and 2 D NMR) and HRESI mass spectrometry.
Techniques in manifold learning: intrinsic dimension and principal surface estimation
Creators: name: Purcell, Michael Patrick
Publisher: name: University of Utah
Year: 2012
Subjects: Intrinsic dimension
Principal surface
Manifold learning

description: Intrinsic dimension estimation is a fundamental problem in manifold learning. In applications, high-dimensional data frequently exhibit an underlying lower-dimensional  structure that, if understood, would allow for faster and more complete analysis of the data. Understanding of this underlying structure requires  first determining what the dimension of that structure is. In this dissertation, a new intrinsic dimension estimator is proposed. This estimator does not estimate the intrinsic dimension of a set directly, rather it estimates the dimension of the sampling measure. This approach acknowledges the fact  that in applications the lower-dimensional structure is unknown; the only information about the set that is available to researchers is what is collected via some sampling method. Theoretical performance guarantees for this estimator are proven that show that the estimator will perform well with only very mild restrictions. Finally, the results of several numerical experiments are provided as evidence that the estimator performs as well or better than the estimators that have been proposed in the literature.  Having determined the intrinsic dimension of a set, it remains to examine the geometry of the underlying lower-dimensional structure. This dissertation examines a new technique called Kernel Map Manifolds that has been proposed by Samuel Gerber to do precisely this. The Kernel Map Manifolds algorithm uses the complementary ideas of principal surfaces and kernel regression to estimate the geometry of the underlying  structure of sample data. This algorithm relies on a conjecture about the nature of the class of minimizers of a distance function. If this conjecture is true, then a gradient descent method can be employed to produce estimated coordinate maps for a principal surface of a distribution. While this conjecture is not addressed directly herein, what is shown is that if the coordinate map of a principal surface of a given distribution is known, then sample data can be used in conjunction with this knowledge to produce accurate estimates of the principal surface thereby showing that if the conjecture is true then the Kernel Map Manifolds algorithm will produce accurate estimates of the underlying lower-dimensional geometry of the set.
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.09.1967, erstellt als zweite Tagesaufnahme um 15 h 40 von Gisèle Evrard-Kesteloot, Observatoire Royal de Belgique in Uccle
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1967

description: Bleistiftzeichnung mit Tinte und Farbstift, erstellt als Zeichnung nach eigener Vorlage in Uccle.
Instrument: Merz-Grubb Refraktor Teleskop (Öffnung 160 mm, f = 2450 mm, projiziertes Sonnenbild D = 25 cm)
Secondary metabolites of Curvularia sp. G6-32, an endophyte of Sapindus saponaria, with antioxidant and anticholinesterasic properties
Creators: name: Polli, Andressa Domingos
name: Ribeiro, Marcos Alessandro dos Santos
name: Garcia, Adriana
name: Polonio, Julio Cesar
name: Santos, Caroline Menicoze
name: Silva, Angela Aparecida
name: Orlandelli, Ravely Casarotti
name: Castro, Juliana Cristina
name: Abreu-Filho, Benício Alves
name: Cabral, Marcia Regina Pereira
name: Sarragiotto, Maria Helena
name: Pamphile, João Alencar
name: Azevedo, João Lúcio
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: In the present study, the biological activity of an extract of the secondary metabolites (E-G6-32) produced by the Curvularia sp. G6-32 endophyte (isolated from the medicinal plant Sapindus saponaria L.) was investigated. The antioxidant potential was confirmed by the DPPH (22.5%) and ABTS (62.7%) assays, and the total phenolic compound content was 40 µg gallic acid equivalents/mg. The extract E-G6-32 displayed good inhibitory activity toward butyrylcholinesterase (BuChE; IC50 = 110 ± 0.05 µg mL−1). The extract E-G6-32 was subjected to spectroscopic and mass spectrometry analyses. Comparison with the literature data confirmed that (-)-asperpentyn (1) was a major component. Asperpentyn belongs to the epoxyquinone family, which has attractive structural complexity, diverse functional groups, and a broad range of biological activities, including specific enzyme inhibitory activity. Our results suggest that Curvularia sp. G6-32 is a promising source of bioactive secondary metabolites and contains (-)-asperpentyn, which has potential pharmaceutical interest.