cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Nanolensing of gamma-ray bursts
Creators: name: Walker, Mark A.
name: Lewis, Geraint F.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: All quasars vary in their optical flux on a time-scale of years, and it has been proposed that these variations are principally due to gravitational lensing by a cosmologically distributed population of planetary mass objects. This interpretation has implications for the observable properties of gamma-ray bursts (GRBs) -- as a source expands across the nano-arcsecond caustic network, variability is expected -- and data on GRBs can be used to test the proposed model of quasar variability. Here we employ an ultra-relativistic blast-wave model of the source, with no intrinsic variations, to study the effects of nanolensing on GRBs. Taken in isolation the light-curves of the caustic crossings are predictable, and we find that a subset of the predicted light-curves (the image-annihilating fold crossings) resemble the ``pulses'' which are commonly seen in long GRBs. Furthermore, for sources at high redshift the expected time between caustic crossings is of order seconds, comparable to the observed time between pulses. These points suggest that it might be possible to model some of the observed variations of GRBs in terms of nanolensing; however, our simulated light-curves exhibit a small depth of modulation compared to what is observed. This means that the GRB data do not significantly constrain the quasar nanolensing model; it also means that the simplest nanolensing model cannot explain the observed GRB ``pulses''. Viable nanolensing models for pulses probably require a large external beam shear. If a viable model can be constructed it would effect a considerable simplification in source modelling and, ironically, it would explain why no macro-lensed GRBs have been identified to date. (Abridged)
description: 28 pages, 12 figures, matches version accepted by ApJ (fixed minor error in fold lens mapping)
REORGANIZING AGRICULTURAL ECONOMICS PROGRAMME AT THE BANGLADESH AGRICULTURAL UNIVERSITY
Creators: name: Elahi, Khandaker Qudrat-I
name: Elahi, Khandaker Qudrat-I
Publisher: name: Unknown
Year: 1986
Subjects: Research and Development/Tech Change/Emerging Technologies

description: The faculty of Agricultural Economics and Rural Sociology was established at the Bangladesh Agricultural University more than twenty years ago in 1963. The main objectives were teaching and Research. The achievement of these objectives is less than satisfactory, because quality of research and training is not very rich. The poor quality of training may be attributed to narrow curricula and outdated syllabuses but the ultimate problem is the defective institution which has resolved into a crisis of leadership. TA this paper, alternative institutional arrangements and curricula axe suggested to improve ft quality of research and training in this faculty.
Multi-Channel Direct Detection of Light Dark Matter: Target Comparison
Creators: name: Griffin, Sinead M.
name: Inzani, Katherine
name: Trickle, Tanner
name: Zhang, Zhengkang
name: Zurek, Kathryn M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Direct detection experiments for light dark matter are making enormous leaps in reaching previously unexplored model space. Several recent proposals rely on collective excitations, where the experimental sensitivity is highly dependent on detailed properties of the target material, well beyond just nucleus mass numbers as in conventional searches. It is thus important to optimize the target choice when considering which experiment to build. We carry out a comparative study of target materials across several detection channels, focusing on electron transitions and single (acoustic or optical) phonon excitations in crystals, as well as the traditional nuclear recoils. We compare materials currently in use in nuclear recoil experiments (Si, Ge, NaI, CsI, CaWO$_4$), a few which have been proposed for light dark matter experiments (GaAs, Al$_2$O$_3$, diamond), as well as 16 other promising polar crystals across all detection channels. We find that target- and dark matter model-dependent reach is largely determined by a small number of material parameters: speed of sound, electronic band gap, mass number, Born effective charge, high frequency dielectric constant, and optical phonon energies. We showcase, for each of the two benchmark models, an exemplary material which has a better reach than in any currently proposed experiment.
description: 28 pages, 18 figures. Updated constraint projections in figures with PhonoDark v1.1.0 (phonodark.caltech.edu)
Why do naked singularities form in gravitational collapse?
Creators: name: Joshi, Pankaj S.
name: Dadhich, Naresh
name: Maartens, Roy
Publisher: name: arXiv
Year: 2001
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate what are the key physical features that cause the development of a naked singularity, rather than a black hole, as the end-state of spherical gravitational collapse. We show that sufficiently strong shearing effects near the singularity delay the formation of the apparent horizon. This exposes the singularity to an external observer, in contrast to a black hole, which is hidden behind an event horizon due to the early formation of an apparent horizon.
description: revised for clarity, new figure included; version accepted by Phys. Rev. D (RC)
Mitigating Internal Instrument Coupling for 21 cm Cosmology I: Temporal and Spectral Modeling in Simulations
Creators: name: Kern, Nicholas S.
name: Parsons, Aaron R.
name: Dillon, Joshua S.
name: Lanman, Adam E.
name: Fagnoni, Nicolas
name: Acedo, Eloy de Lera
Publisher: name: arXiv
Year: 2019
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We study the behavior of internal signal chain reflections and antenna cross coupling as systematics for 21 cm cosmological surveys. We outline the mathematics for how these systematics appear in interferometric visibilities and describe their phenomenology. We then describe techniques for modeling and removing these systematics without attenuating the 21 cm signal in the data. This has critical implications for low-frequency radio surveys aiming to characterize the 21cm signal from the Epoch of Reionization and Cosmic Dawn, as systematics can cause bright foreground emission to contaminate the EoR window and prohibit a robust detection. We also quantify the signal loss properties of the systematic modeling algorithms, and show that our techniques demonstrate resistance against EoR signal loss. In a companion paper, we demonstrate these methods on data from the Hydrogen Epoch of Reionization Array as a proof-of-concept.
description: Accepted to ApJ
How does the human visual system compare the speeds of spatially separated objects?
Creators: name: Danilova, M. V.
name: Takahashi, C.
name: Mollon, J. D.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: subject: Research Article
subject: Engineering and technology
subject: FOS: Engineering and technology
subject: Biology and life sciences
subject: Social sciences
subject: FOS: Social sciences
subject: Computer and information sciences
subject: FOS: Computer and information sciences
subject: Medicine and health sciences

description: We measured psychophysical thresholds for discriminating the speeds of two arrays of moving dots. The arrays could be juxtaposed or could be spatially separated by up to 10 degrees of visual angle, eccentricity being held constant. We found that the precision of the judgments varied little with separation. Moreover, the function relating threshold to separation was similar whether the arrays moved in the same, in opposite or in orthogonal directions. And there was no significant difference in threshold whether the two stimuli were initially presented to the same cerebral hemisphere or to opposite ones. How are human observers able to compare stimuli that fall at well separated positions in the visual field? We consider two classes of explanation: (i) Observers’ judgments might be based directly on the signals of dedicated ‘comparator neurons’, i.e. neurons drawing inputs of opposite sign from local regions of the visual field. (ii) Signals about local features might be transmitted to the site of comparison by a shared ‘cerebral bus’, where the same physical substrate carries different information from moment to moment. The minimal effects of proximity and direction (which might be expected to influence local detectors of relative motion), and the combinatorial explosion in the number of comparator neurons that would be required by (i), lead us to favor models of type (ii).
Positive Freedom in Networked Capitalism: An Empirical Analysis
Creators: name: Carbonai, Davide
name: Drago, Carlo
name: Carbonai, Davide
name: Drago, Carlo
Publisher: name: Unknown
Year: 2015
Subjects: subject: Political Economy
subject: Social Network Analysis
subject: Antitrust Policies
subject: Interlocking Directorates
subject: Europe
subject: Positive Freedom
subject: Negative Freedom

description: The article proposes a social network analysis of the main European capitalisms and its correspondence with an index of economic freedom. The analysis relates to two kinds of economic liberties taken from the concept of freedom formulated by Isaiah Berlin. While the first kind of freedom (negative freedom) depends on the external system (e.g. the constraints on the firm defined by the regulations), the second refers to the internal obligations within the business system itself that prevent the free exercise of business (positive freedom): specifically, the social network, in which the company is embedded. After an operationalization of the two concepts of freedom, the analysis of a comprehensive database allows us to explore the relationship between the two kinds of freedom.
Photoproductions of dileptons, photons, and light vector mesons in p-p, p-Pb, and Pb-Pb collisions at Large Hadron Collider energies
Creators: name: Ma, Zhi-Lei
name: Lu, Zhun
name: Zhu, Jia-Qing
name: Zhang, Li
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The photoproduction of large $p_{T}$ dileptons, photons and light vector mesons in p-p, p-Pb and Pb-Pb collisions at LHC energies is studied, where the fragmentation processes and the ultra-incoherent photon channel are included. An exact treatment is developed for photoproduction processes in heavy ion collisions, which recovers the equivalent photon approximation (EPA) in the limit $Q^{2}\rightarrow0$ and can avoid double counting effectively. The full kinematical relations are also achieved. We present the results as the distributions in $Q^{2}$, $p_{T}$ and $y_{r}$, the total cross sections are also estimated. The numerical results indicate that: the contribution of photoproduction processes is evident in the large $p_{T}$ and $y_{r}$ regions, and starts to play a fundamental role in p-Pb collisions. The ultra-incoherent photon emission is a important channel of photoproduction processes, which can provide the meaningful contributions. EPA is only applicable in small $y$ and $Q^{2}$ domains, and is very sensitive to the values of $y_{\mathrm{max}}$ and $Q^{2}_{\mathrm{max}}$. The EPA errors appear when $y>0.29$ and $Q^{2}>0.1~\mathrm{GeV}^{2}$, and are rather serious in p-Pb and Pb-Pb collisions. When dealing with widely kinematical regions, the exact treatment needs to be adopted.
description: 19 pages, 10 figures
MOESM6 of MicroRNA profiling in adults with high-functioning autism spectrum disorder
Creators: name: Nakata, Masatoshi
name: Kimura, Ryo
name: Funabiki, Yasuko
name: Tomonari Awaya
name: Murai, Toshiya
name: Hagiwara, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 6: Figure S1. Blood cell composition. The proportions of six blood cell subtypes [B cells, CD8 T cells, CD4 T cells, natural killer (NK) cells, monocytes, and granulocytes] were estimated by Housemanâ s algorithm using DNA methylation array data. A Studentâ s t-test was used for statistical analysis.
Additional file 1 of BDNF promotes mouse follicular development and reverses ovarian aging by promoting cell proliferation
Creators: name: Liu, Bin
name: Liu, Yongjie
name: Li, Shuman
name: Chen, Pingping
name: Zhang, Jun
name: Feng, Liping
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Supplementary Material 1
Cronin Effect in Hadron Production off Nuclei
Creators: name: Kopeliovich, B. Z.
name: Nemchik, J.
name: Schaefer, A.
name: Tarasov, A. V.
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Recent data from RHIC for high-$p_T$ hadrons in gold-gold collisions raised again the long standing problem of quantitatively understanding the Cronin effect, i.e. nuclear enhancement of high-$p_T$ hadrons due to multiple interactions in nuclear matter. In nucleus-nucleus collisions this effect has to be reliably calculated as baseline for a signal of new physics in high-$p_T$ hadron production. The only possibility to test models is to compare with available data for $pA$ collisions, however, all existing models for the Cronin effect rely on a fit to the data to be explained. We develop a phenomenological description based on the light-cone QCD-dipole approach which allows to explain available data without fitting to them and to provide predictions for $pA$ collisions at RHIC and LHC. We point out that the mechanism causing Cronin effect drastically changes between the energies of fixed target experiments and RHIC-LHC. High-$p_T$ hadrons are produced incoherently on different nucleons at low energies, whereas the production amplitudes interfere if the energy is sufficiently high.
description: the final version to appear in Phys. Rev. Lett
AGRICULTURAL ECONOMICS RESEARCH IN CONTEMPORARY BANGLADESH: THE STATE OF THE ART
Creators: name: Gill, Gerard J.
name: Gill, Gerard J.
Publisher: name: Unknown
Year: 1986
Subjects: Research and Development/Tech Change/Emerging Technologies

description: This paper reflects the personal and deliberately provocative views of a non-Bangladeshi who has worked here for more than seven years. A number of problem areas for the future development of the profession are identified. These include the poor development of library facilities, a lack of attention to macro-level research, undue reliance on questionnaire surveys, and number of unwarranted biases. Prominent among the latter are a bias towards crops, a lack of attention to women's role in agriculture and a funding bias, which encourages project evaluation at the expense of research on the traditional sectors. Too many surveys are ‘one-off’ ‘qnick-and dirty’ studies which are weak in analysis and inadequately link with theory. It is suggested that professional bodies in the country should play a leading role in addressing the challenges implicit in these observations.
title: Boundary Integral Equation Method for Electrostatic Field Prediction in Piecewise-Homogeneous Electrolytes
Creators: name: Pratt, Christopher Keith
Publisher: name: University of Kentucky Libraries
Year: 2021
Subjects: subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This thesis presents a method to predict electrostatic fields, potentials, and currents in regions containing piecewise-homogeneous electrolytes. Additionally, an efficient electric field calculation is presented. A boundary integral equation is formulated for the boundary potentials and currents and is discretized using the Locally Corrected Nyström method. Solution convergence with respect to the mesh discretization and basis order is investigated. The techniques are validated through analysis of problems with either analytic solutions, with published data, or with other solution methods.
description: © 2021 Christopher Keith Pratt
RELATIVE PROFITABILITY OF COTTON AND ITS COMPETING CROPS IN BANGLADESH
Creators: name: Raha, S. K.
name: Talukder, M. R. K.
name: Rahman, M. H.
name: Raha, S. K.
name: Talukder, M. R. K.
name: Rahman, M. H.
Publisher: name: Unknown
Year: 1986
Subjects: Research and Development/Tech Change/Emerging Technologies

description: This study is based on a sample of 242 cotton growers located in eight upazilas of four old districts. Cotton was found more profitable that, its competing crops except tobacco. Tobacco is not liked by many farmers because it is associated with more problems. Despite sincere effort of the cotton development board, the target of production and acreage were not achieved because of lower price of cotton, paucity of fund, technical know how and irrigation facility. Production target can be achieved by ensuring reasonable price to cotton growers.
Current-induced highly dissipative domains in high Tc thin films
Creators: name: Reymond, S.
name: Antognazza, L.
name: Decroux, M.
name: Koller, E.
name: Reinert, P.
name: Fischer, O.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We have investigated the resistive response of high Tc thin films submitted to a high density of current. For this purpose, current pulses were applied into bridges made of Nd(1.15)Ba(1.85)Cu3O7 and Bi2Sr2CaCu2O8. By recording the time dependent voltage, we observe that at a certain critical current j*, a highly dissipative domain develops somewhere along the bridge. The successive formation of these domains produces stepped I-V characteristics. We present evidences that these domains are not regions with a temperature above Tc, as for hot spots. In fact this phenomenon appears to be analog to the nucleation of phase-slip centers observed in conventional superconductors near Tc, but here in contrast they appear in a wide temperature range. Under some conditions, these domains will propagate and destroy the superconductivity within the whole sample. We have measured the temperature dependence of j* and found a similar behavior in the two investigated compounds. This temperature dependence is just the one expected for the depairing current, but the amplitude is about 100 times smaller.
description: 9 pages, 9 figures, Revtex, to appear in Phys. Rev. B
Paragiopagurus rugosus
Creators: name: Castro, Peter
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Parapaguridae
Paragiopagurus
Paragiopagurus rugosus

description: Paragiopagurus rugosus (de Saint Laurent, 1972)
 Parapagurus rugosus de Saint Laurent, 1972: 112, figs. 6, 21 [type locality: “Hawaї;” holotype: USNM 168308; paratype USNM 168312].
 Remarks. Described from the Hawaiian Is. but no subsequent records are known from the archipelago.
 Taxonomy. de Saint Laurent (1972)
 Geographical distribution. Only known from the Hawaiian Is.
 Habitat. Bathyal, 240–270 m.
description: Published as part of Castro, Peter, 2011, Catalog of the anomuran and brachyuran crabs (Crustacea: Decapoda: Anomura, Brachyura) of the Hawaiian Islands 2947, pp. 1-154 in Zootaxa 2947 (1) on page 30, DOI: 10.11646/zootaxa.2947.1.1, http://zenodo.org/record/5283044
Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses
Creators: name: Wallace, Chris
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research Article
Biology and life sciences
Research and analysis methods
Medicine and health sciences

description: Horizontal integration of summary statistics from different GWAS traits can be used to evaluate evidence for their shared genetic causality. One popular method to do this is a Bayesian method, coloc, which is attractive in requiring only GWAS summary statistics and no linkage disequilibrium estimates and is now being used routinely to perform thousands of comparisons between traits. Here we show that while most users do not adjust default software values, misspecification of prior parameters can substantially alter posterior inference. We suggest data driven methods to derive sensible prior values, and demonstrate how sensitivity analysis can be used to assess robustness of posterior inference. The flexibility of coloc comes at the expense of an unrealistic assumption of a single causal variant per trait. This assumption can be relaxed by stepwise conditioning, but this requires external software and an LD matrix aligned to study alleles. We have now implemented conditioning within coloc, and propose a new alternative method, masking, that does not require LD and approximates conditioning when causal variants are independent. Importantly, masking can be used in combination with conditioning where allelically aligned LD estimates are available for only a single trait. We have implemented these developments in a new version of coloc which we hope will enable more informed choice of priors and overcome the restriction of the single causal variant assumptions in coloc analysis.
Single-cell stochastic gene expression kinetics with coupled positive-plus-negative feedback
Creators: name: Jia, Chen
name: Wang, Le Yi
name: Yin, George G.
name: Zhang, Michael Q.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Molecular Networks (q-bio.MN)
subject: Probability (math.PR)
subject: Biological Physics (physics.bio-ph)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Here we investigate single-cell stochastic gene expression kinetics in a minimal coupled gene circuit with positive-plus-negative feedback. A triphasic stochastic bifurcation upon the increasing ratio of the positive and negative feedback strengths is observed, which reveals a strong synergistic interaction between positive and negative feedback loops. We discover that coupled positive-plus-negative feedback amplifies gene expression mean but reduces gene expression noise over a wide range of feedback strengths when promoter switching is relatively slow, stabilizing gene expression around a relatively high level. In addition, we study two types of macroscopic limits of the discrete chemical master equation model: the Kurtz limit applies to proteins with large burst frequencies and the Lévy limit applies to proteins with large burst sizes. We derive the analytic steady-state distributions of the protein abundance in a coupled gene circuit for both the discrete model and its two macroscopic limits, generalizing the results obtained in [Chaos 26:043108, 2016]. We also obtain the analytic time-dependent protein distribution for the classical Friedman-Cai-Xie random bursting model proposed in [Phys. Rev. Lett. 97:168302, 2006]. Our analytic results are further applied to study the structure of gene expression noise in a coupled gene circuit and a complete decomposition of noise in terms of five different biophysical origins is provided.
description: 27 pages, 7 figures
Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes
Creators: name: F. C. Lopes, Amanda
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Review
Endocrinology and Metabolic Epigenetics
DNA methylation
Nucleus
Mitochondria
Metabolism
DNA
Haplogroups

description: Abstract: Mitochondria are controlled by the coordination of two genomes: the mitochondrial and the nuclear DNA. As such, variations in nuclear gene expression as a consequence of mutations and epigenetic modifications can affect mitochondrial functionality. Conversely, the opposite could also be true. However, the relationship between mitochondrial dysfunction and epigenetics, such as nuclear DNA methylation, remains largely unexplored. Mitochondria function as central metabolic hubs controlling some of the main substrates involved in nuclear DNA methylation, via the one carbon metabolism, the tricarboxylic acid cycle and the methionine pathway. Here, we review key findings and highlight new areas of focus, with the ultimate goal of getting one step closer to understanding the genomic effects of mitochondrial dysfunction on nuclear epigenetic landscapes.
A Henkin-style completeness proof for the modal logic S5
Creators: name: Bentzen, Bruno
Publisher: name: arXiv
Year: 2019
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: This paper presents a recent formalization of a Henkin-style completeness proof for the propositional modal logic S5 using the Lean theorem prover. The proof formalized is close to that of Hughes and Cresswell, but the system, based on a different choice of axioms, is better described as a Mendelson system augmented with axiom schemes for K, T, S4, and B, and the necessitation rule as a rule of inference. The language has the false and implication as the only primitive logical connectives and necessity as the only primitive modal operator. The full source code is available online at https://github.com/bbentzen/mpl/ and has been typechecked with Lean 3.4.2.
MOESM7 of MicroRNA profiling in adults with high-functioning autism spectrum disorder
Creators: name: Nakata, Masatoshi
name: Kimura, Ryo
name: Funabiki, Yasuko
name: Tomonari Awaya
name: Murai, Toshiya
name: Hagiwara, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 7. Materials and Methods.
Additional file 1 of Effects of Keluoxin capsule combined with losartan potassium on diabetic kidney disease: study protocol for a randomized double-blind placebo-controlled multicenter clinical trial
Creators: name: Wu, Rui
name: Wei, Fan
name: Qu, Lianlian
name: Bai, Litao
name: Li, Jun
name: Li, Fei
name: Yan, Weitian
name: Wang, Qiuhong
name: Wei, Junping
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1: Supplementary Table 1. Description of the roles for the study groups.
MOESM3 of MicroRNA profiling in adults with high-functioning autism spectrum disorder
Creators: name: Nakata, Masatoshi
name: Kimura, Ryo
name: Funabiki, Yasuko
name: Tomonari Awaya
name: Murai, Toshiya
name: Hagiwara, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3: Table S3. Correlations between miR-6126 expression and IQ scores.
Paragiopagurus ruticheles
Creators: name: Castro, Peter
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Parapaguridae
Paragiopagurus
Paragiopagurus ruticheles

description: Paragiopagurus ruticheles (A. Milne-Edwards, 1891)
 Eupagurus ruticheles A. Milne-Edwards, 1891: 133 [type locality: Azores; syntypes: MOM].
 Hawaiian Is. record:
 Parapagurus ruticheles (A. Milne-Edwards, 1891) — de Saint Laurent 1972: 112 [H.I.].
 Taxonomy. Lemaitre (1996)
 Geographical distribution. Across Indo-West Pacific region; eastern Atlantic Ocean.
 Habitat. Bathyal, 200–1400 m.
description: Published as part of Castro, Peter, 2011, Catalog of the anomuran and brachyuran crabs (Crustacea: Decapoda: Anomura, Brachyura) of the Hawaiian Islands 2947, pp. 1-154 in Zootaxa 2947 (1) on page 30, DOI: 10.11646/zootaxa.2947.1.1, http://zenodo.org/record/5283044
Quantum Einstein's Equations and Constraints Algebra
Creators: name: Shojai, Fatimah
name: Shojai, Ali
Publisher: name: arXiv
Year: 2001
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper we shall address this problem: Is quantum gravity constraints algebra closed and what are the quantum Einstein equations. We shall investigate this problem in the de-Broglie--Bohm quantum theory framework. It is shown that the constraint algebra is weakly closed and the quantum Einstein's equations are derived.
description: 13 pages, No figure, RevTeX. To appear in Pramana J. Phys., 2001
title: WORK-RELATED CHANGES IN THE TRUNK STIFFNESS OF NURSING PERSONNEL
Creators: name: Tyler, Clare
Publisher: name: University of Kentucky Libraries
Year: 2021
Subjects: subject: FOS: Medical engineering

description: Low back pain (LBP) is a significant issue related to spinal stability and, therefore, to trunk stiffness. Due to the nature of their work, nursing personnel are exposed to potential risk factors for LBP, such as lifting and trunk flexion, which have been reported in the literature to lead to decreases in trunk stiffness. Consequently, the purpose of this study was to investigate potential occupational effects on the trunk stiffness in nursing personnel. Twenty-four nursing personnel participated in this study and completed two sessions (pre-shift and post-shift) during which two passive flexion tests (with and without an ~7.5-lb load) were conducted to characterize their trunk stiffness in upright standing. Overall, no work-related changes in trunk stiffness were found in this study. However, trunk stiffness was higher for the loading condition with the load being held in the subjects’ hands than for the condition without this load (p=0.002). Finding no work-related changes in trunk stiffness may have resulted from the heterogeneity of the recruited sample of nursing personnel and the potential recovery of trunk stiffness before their post-shift data collection sessions. Future studies should try to reduce participant heterogeneity and perform data collection closer to where the participants work.
description: © 2021 Clare Tyler
MOESM4 of MicroRNA profiling in adults with high-functioning autism spectrum disorder
Creators: name: Nakata, Masatoshi
name: Kimura, Ryo
name: Funabiki, Yasuko
name: Tomonari Awaya
name: Murai, Toshiya
name: Hagiwara, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 4: Table S4. Predicted target genes of miR-6126.
LCAO-TDDFT-$k$-$ω$: Spectroscopy in the Optical Limit
Creators: name: Lyon, Keenan
name: Preciado-Rivas, María Rosa
name: Mowbray, Duncan John
name: Despoja, Vito
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Understanding, optimizing, and controlling the optical absorption process, exciton gemination, and electron-hole separation and conduction in low dimensional systems is a fundamental problem in materials science. However, robust and efficient methods capable of modelling the optical absorbance of low dimensional macromolecular systems and providing physical insight into the processes involved have remained elusive. We employ a highly efficient linear combination of atomic orbitals (LCAOs) representation of the Kohn--Sham (KS) orbitals within time dependent density functional theory (TDDFT) in the reciprocal space ($k$) and frequency ($ω$) domains, as implemented within our LCAO-TDDFT-$k$-$ω$ code, and apply the derivative discontinuity correction of the exchange functional $Δ_x$ to the KS eigenenergies. In so doing we are able to provide a semi-quantitative description of the optical absorption, conductivity, and polarizability spectra for prototypical 0D, 1D, 2D, and 3D systems within the optical limit ($\|\bf{q}\|\to0^+$) as compared to both available measurements and from solving the Bethe$-$Salpeter equation with quasiparticle $G_0 W_0$ eigenvalues ($G_0 W_0$-BSE). Specifically, we consider 0D fullerene (C$_{60}$), 1D metallic (10,0) and semiconducting (10,10) single-walled carbon nanotubes (SWCNTs), 2D graphene (GR) and phosphorene (PN), and 3D rutile (R-TiO$_2$) and anatase (A-TiO$_2$). For each system, we also employ the spatially resolved electron-hole density to provide direct physical insight into the nature of their optical excitations. These results demonstrate the reliability, applicability, efficiency, and robustness of our LCAO-TDDFT-$k$-$ω$ code, and open the pathway to the computational design of macromolecular systems for optoelectronic, photovoltaic, and photocatalytic applications $in$ $silico$.
description: 15 pages, 13 figures
The hard body goes soft : anxious men and masculinity in the films of the Clinton era
Creators: name: Di Mattia, Joanna Luisa
Publisher: name: Monash University
Year: 2021

description: This thesis was scanned from the print manuscript for digital preservation and is copyright the author.
 Researchers can access this thesis by asking their local university, institution or public library to
 make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Paragiopagurus tuberculosus
Creators: name: Castro, Peter
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Malacostraca
Decapoda
Parapaguridae
Paragiopagurus
Paragiopagurus tuberculosus

description: Paragiopagurus tuberculosus (de Saint Laurent, 1972)
 Parapagurus tuberculosus de Saint Laurent, 1972: 118, figs 11, 25 [type locality: Laysan; holotype: USNM 168906].
 Taxonomy. de Saint Laurent (1972)
 Geographical distribution. Only known from the Hawaiian Is.
 Habitat. Bathyal, 220–300 m.
description: Published as part of Castro, Peter, 2011, Catalog of the anomuran and brachyuran crabs (Crustacea: Decapoda: Anomura, Brachyura) of the Hawaiian Islands 2947, pp. 1-154 in Zootaxa 2947 (1) on page 30, DOI: 10.11646/zootaxa.2947.1.1, http://zenodo.org/record/5283044
Status of the KASCADE-Grande Experiment
Creators: name: al., K. -H. Kampert et
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The status and capabilities of the KASCADE-Grande extensive air shower experiment are presented. The installation is located at Forschungszentrum Karlsruhe and comprises a large collecting area (0.5 km^2) electromagnetic array (Grande) operated jointly with the existing KASCADE detectors. KASCADE-Grande will cover the primary energy range 10^16 eV < E_0 < 10^18 eV overlapping with KASCADE around 10^16 eV, thus providing continuous information on the primary energy and mass of cosmic rays from 3x10^14 eV up to 10^18 eV. The major goal of the measurements is the unambiguous observation of the``iron knee'' expected in the cosmic ray spectrum at E_k^{Fe} ~ 10^17 eV.
description: Proceedings to "XII International Symposium on Very High Energy Cosmic Ray Interactions", CERN, Geneva, Switzerland 15-20 July 2002, (5 pages, 4 figures)
MOESM5 of MicroRNA profiling in adults with high-functioning autism spectrum disorder
Creators: name: Nakata, Masatoshi
name: Kimura, Ryo
name: Funabiki, Yasuko
name: Tomonari Awaya
name: Murai, Toshiya
name: Hagiwara, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 5: Table S5. GO and KEGG pathway analysis of target genes of miR-6126.
Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56 Lck regulates T-cell activation independently of Lck/CD45 interactions
Creators: name: Kästle, Matthias
name: Merten, Camilla
name: Hartig, Roland
name: Kaehne, Thilo
name: Liaunardy-Jopeace, Ardiyanto
name: Woessner, Nadine M.
name: Schamel, Wolfgang W.
name: James, John
name: Minguet, Susana
name: Simeoni, Luca
name: Schraven, Burkhart
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research
Lck
T-cell activation
TCR signaling
Zap70
Knock-in mice
Y192
Signal transduction
PLA

description: Funder: DFG
description: Funder: Projekt DEAL
description: Abstract: Background: Upon engagement of the T-cell receptor (TCR), the Src-family protein tyrosine kinase p56Lck phosphorylates components of the TCR (e.g. the TCRζ chains), thereby initiating T-cell activation. The enzymatic activity of Lck is primarily regulated via reversible and dynamic phosphorylation of two tyrosine residues, Y394 and Y505. Lck possesses an additional highly conserved tyrosine Y192, located within the SH2 domain, whose role in T-cell activation is not fully understood. Methods: Knock-in mice expressing a phospho-mimetic (Y192E) form of Lck were generated. Cellular and biochemical characterization was performed to elucidate the function of Y192 in primary T cells. HEK 293T and Jurkat T cells were used for in vitro studies. Results: Co-immunoprecipitation studies and biochemical analyses using T cells from LckY192E knock-in mice revealed a diminished binding of LckY192E to CD45 and a concomitant hyperphosphorylation of Y505, thus corroborating previous data obtained in Jurkat T cells. Surprisingly however, in vitro kinase assays showed that LckY192E possesses a normal enzymatic activity in human and murine T cells. FLIM/FRET measurements employing an LckY192E biosensor further indicated that the steady state conformation of the LckY192E mutant is similar to Lckwt. These data suggest that Y192 might regulate Lck functions also independently from the Lck/CD45-association. Indeed, when LckY192E was expressed in CD45−/−/Csk−/− non-T cells (HEK 293T cells), phosphorylation of Y505 was similar to Lckwt, but LckY192E still failed to optimally phosphorylate and activate the Lck downstream substrate ZAP70. Furthermore, LckY19E was recruited less to CD3 after TCR stimulation. Conclusions: Taken together, phosphorylation of Y192 regulates Lck functions in T cells at least twofold, by preventing Lck association to CD45 and by modulating ligand-induced recruitment of Lck to the TCR. Major findings: Our data change the current view on the function of Y192 and suggest that Y192 also regulates Lck activity in a manner independent of Y505 phosphorylation. Dm4iGs5nWD8FkGrYCfJL2MVideo Abstract
Superresolving the kidney—a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier
Creators: name: Wunderlich, Lucia C. S.
name: Ströhl, Florian
name: Ströhl, Stefan
name: Vanderpoorten, Oliver
name: Mascheroni, Luca
name: Kaminski, Clemens F.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Research Paper
Kidney
Nephrin
Podocyte foot processes
Super-resolution microscopy
Fluorescence microscopy
Formalin-fixed paraffin-embedded

description: Funder: European Research Council via Marie Skłodowska Curie Action Individual Fellowship
description: Funder: Erasmus+
description: Funder: Otto Bayer Fellowship
description: Funder: MedImmune; doi: http://dx.doi.org/10.13039/501100004628
description: Funder: Infinitus China Ltd
description: Funder: European Molecular Biology Organization; doi: http://dx.doi.org/10.13039/100004410
description: Abstract: Immunofluorescence microscopy is routinely used in the diagnosis of and research on renal impairments. However, this highly specific technique is restricted in its maximum resolution to about 250 nm in the lateral and 700 nm in the axial directions and thus not sufficient to investigate the fine subcellular structure of the kidney’s glomerular filtration barrier. In contrast, electron microscopy offers high resolution, but this comes at the cost of poor preservation of immunogenic epitopes and antibody penetration alongside a low throughput. Many of these drawbacks were overcome with the advent of super-resolution microscopy methods. So far, four different super-resolution approaches have been used to study the kidney: single-molecule localization microscopy (SMLM), stimulated emission depletion (STED) microscopy, structured illumination microscopy (SIM), and expansion microscopy (ExM), however, using different preservation methods and widely varying labelling strategies. In this work, all four methods were applied and critically compared on kidney slices obtained from samples treated with the most commonly used preservation technique: fixation by formalin and embedding in paraffin (FFPE). Strengths and weaknesses, as well as the practicalities of each method, are discussed to enable users of super-resolution microscopy in renal research make an informed decision on the best choice of technique. The methods discussed enable the efficient investigation of biopsies stored in kidney banks around the world. Graphical abstract
No scalar hair in nonminimal derivative coupling model for Neumann and Dirichlet reflecting star
Creators: name: Sadjadi, H. Mohseni
name: Khodaei, M.
Publisher: name: arXiv
Year: 2019
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the existence of scalar hair in the background of a reflecting star. The kinetic part of the scalar field is nonminimally coupled to the Einstein tensor. For both the Dirichlet and the Neumann boundary conditions, we study the no-hair theorem. For the massless case, we show that there is no scalar hair, and in the massive case conditions leading to the no-hair theorem are specified.
description: 10 pages, typos corrected
Long-Time Tails and Anomalous Slowing Down in the Relaxation of Spatially Inhomogeneous Excitations in Quantum Spin Chains
Creators: name: Berim, G. O.
name: Berim, S.
name: Cabrera, G. G.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Exact analytic calculations in spin-1/2 XY chains, show the presence of long-time tails in the asymptotic dynamics of spatially inhomogeneous excitations. The decay of inhomogeneities, for $t\to \infty $, is given in the form of a power law \[ (t/τ_{Q}) ^{-ν_{Q}} \] where the relaxation time $τ_{Q}$ and the exponent $ν_{Q}$ depend on the wave vector $Q$, characterizing the spatial modulation of the initial excitation. We consider several variants of the XY model (dimerized, with staggered magnetic field, with bond alternation, and with isotropic and uniform interactions), that are grouped into two families, whether the energy spectrum has a gap or not. Once the initial condition is given, the non-equilibrium problem for the magnetization is solved in closed form, without any other assumption. The long-time behavior for $t\to \infty $ can be obtained systematically in a form of an asymptotic series through the stationary phase method. We found that gapped models show critical behavior with respect to $Q$, in the sense that there exist critical values $Q_{c}$, where the relaxation time $τ_{Q}$ diverges and the exponent $ν_{Q}$ changes discontinuously. At those points, a slowing down of the relaxation process is induced, similarly to phenomena occurring near phase transitions. Long-lived excitations are identified as incommensurate spin density waves that emerge in systems undergoing the Peierls transition. In contrast, gapless models do not present the above anomalies as a function of the wave vector $Q$.
description: 25 pages, 2 postscript figures. Manuscript submitted to Physical Review B
Additional file 3 of Effects of Keluoxin capsule combined with losartan potassium on diabetic kidney disease: study protocol for a randomized double-blind placebo-controlled multicenter clinical trial
Creators: name: Wu, Rui
name: Wei, Fan
name: Qu, Lianlian
name: Bai, Litao
name: Li, Jun
name: Li, Fei
name: Yan, Weitian
name: Wang, Qiuhong
name: Wei, Junping
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 3:. Consent form.
title: ACL Injury, a Time Course Study of Transcriptional Changes
Creators: name: Carter, Thomas
Publisher: name: University of Kentucky Libraries
Year: 2021
Subjects: subject: FOS: Basic medicine

description: ACL tear is a common injury in the United States with a significant cost and time burden during recovery; reconstructive surgery often results in weakened quadricep muscle and higher risk of posttraumatic osteoarthritis. Prior research has highlighted cellular derangements within the quadriceps after ACL injury and reconstruction, but the early molecular effectors of cellular dysfunction remain to be identified. To further understand the molecular effectors of quadriceps dysfunction following ACL injury, this study aims to quantify the timing and magnitude of transcriptional differences between the quadriceps muscle of injured and contralateral non-injured limbs. These data will provide insight into the early molecular events after ACL injury to identify potential treatment points in our pre-clinical ACL injury model. Immunohistochemical images and transcriptional activity assays from mouse quadriceps following surgical ACL transection were taken after one, three, seven, and ten days. These data were compared with their contralateral non-injured limb. Results showed early myonuclear transcriptional differences precede discernable atrophy. These data provide a time course of early molecular changes after ACL injury that will aid in optimizing the delivery of therapeutics to mitigate or rescue deficits within the injury limb muscle.
description: © 2021 Thomas Carter
MOESM2 of MicroRNA profiling in adults with high-functioning autism spectrum disorder
Creators: name: Nakata, Masatoshi
name: Kimura, Ryo
name: Funabiki, Yasuko
name: Tomonari Awaya
name: Murai, Toshiya
name: Hagiwara, Masatoshi
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 2: Table S2. Differential miRNA expression profiles.