cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
THE LONG NON-CODING FOXP3 REGULATES CELL IDENTITY AND FUNCTION OF T REGULATORY LYMPHOCYTES STABILIZING THE KEY TRANSCRITPTION FACTOR FOXP3
Creators: name: DARDANELLI, ALESSIA
Publisher: name: Universit� degli Studi di Milano
Year: 2019

description: Abstract The human immune system is a suitable context to study plasticity in response to environmental stimuli. Differentiation of Na�ve cells into specialized subsets guarantees the proper immune system function. These cellular subsets were once considered as terminally differentiated, but recent findings, showed that they display a high degree of plasticity, whose underlying molecular mechanisms are still poorly understood. In this context, CD4+ T regulatory lymphocytes (Treg) are the principal actors in the regulation of immune responses and maintenance of immunological self-tolerance thanks to their peculiar suppressive function. Treg cells dysfunction is associated to autoimmune pathologies, inflammatory diseases and cancer. Their inherent plasticity could be exploited as a promising therapeutic opportunity to modulate their differentiation and function in the context of several immune-mediated diseases. A better characterization of the molecular mechanism underlying plasticity is thus compelling. Long non-coding RNAs (lncRNAs) has been identified as novel players in the modulation of cell plasticity and in the maintenance of cell identity. These features, along with their cellular specificity, brought lncRNAs to the fore as novel and promising therapeutic targets. In this study, we demonstrate that the expression of lncFOXP3, a CD4+ T regulatory specific lncRNAs located upstream of FOXP3 gene, is crucial for the maintenance of Treg phenotype and proper function. Expression of lncFOXP3 correlates with FoxP3, the master transcription factor of Treg cells, but the two transcripts are not co-regulated. Functional experiments revealed that lncFOXP3 down-regulation reduces FoxP3 protein levels and, moreover, impacts on Treg suppressive activity. Finally, the analysis of lncFOXP3 protein interactors highlighted the association with Ubiquitin-specific-processing protease 7 (USP7), indicating its putative role in the maintenance of FoxP3 protein stability. Our results suggest a direct involvement of lncRNAs in the maintenance of Treg cell proper function. Therefore, modulation of lncRNAs could potentially be exploited to either enhance or quench Treg cell suppressive function in the treatment of autoimmune diseases, cancer or immunodeficiencies.
Chemical diversity in the genus Gambierdiscus, with a focus on Ciguatoxins and Maitotoxins
Creators: name: Hess, Philipp
name: Pisapia, Francesco
name: Sibat, Manoëlla
name: Séchet, Véronique
name: Lhaute, Korian
name: Watanabe, Ryuichi
name: Suzuki, T.
name: Ferron, Pierre-Jean
name: Fessard, Valérie
name: Roullier, Catherine
name: Fraga, Santiago
name: Litaker, Richard Wayne
name: Holland, William Chris
name: Nascimento, Silvia M.
name: Adachi, Masao
name: Nishimura, T.
name: Herrencknecht, Christine
Publisher: name: Zenodo
Year: 2017
Subjects: Ciguatera
maitotoxins
ciguatoxins
Gambierdiscus

description: The genus Gambierdiscus is a complex and diverse group of marine dinoflagellates that produce a range of bioactive compounds, including ciguatoxins and maitotoxins. These toxins can accumulate in the food chain, leading to ciguatera poisoning in humans who consume contaminated fish. Recent research has highlighted the chemical diversity within the genus Gambierdiscus, with different strains producing distinct sets of toxins. This diversity presents challenges for the development of effective detection and management strategies for ciguatera, but also offers opportunities for the discovery of new bioactive compounds with potential applications in medicine and other fields. Understanding the chemical diversity of Gambierdiscus and its associated toxins is therefore an important area of research with implications for public health and biotechnology.
Convergence of Parareal for the Navier-Stokes equations depending on the Reynolds number
Creators: name: Steiner, Johannes
name: Ruprecht, Daniel
name: Speck, Robert
name: Krause, Rolf
Publisher: name: arXiv
Year: 2013
Subjects: subject: Numerical Analysis (math.NA)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: The paper presents first a linear stability analysis for the time-parallel Parareal method, using an IMEX Euler as coarse and a Runge-Kutta-3 method as fine propagator, confirming that dominant imaginary eigenvalues negatively affect Parareal's convergence. This suggests that when Parareal is applied to the nonlinear Navier-Stokes equations, problems for small viscosities could arise. Numerical results for a driven cavity benchmark are presented, confirming that Parareal's convergence can indeed deteriorate as viscosity decreases and the flow becomes increasingly dominated by convection. The effect is found to strongly depend on the spatial resolution.
A New Key Establishment Protocol and its Application in Pay-TV Systems
Creators: name: Roelse, Peter
Publisher: name: arXiv
Year: 2013
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences
subject: 68M12, 94A60

description: A pay-TV consumer uses a decoder to access encrypted digital content. To this end, the decoder contains a chip capable of decrypting the content if provisioned with the appropriate content decryption keys. A key establishment protocol is used to secure the delivery of the content decryption keys to the chip. This paper presents a new protocol and shows how the protocol can be applied in a pay-TV system. Compared to existing protocols, the presented solution reduces the risk that decoders need to be replaced in order to correct a security breach. The new protocol has recently been incorporated in an ETSI standard.
description: 6 pages, 3 figures
Hamiltonian dynamics and gauge symmetry for three-dimensional Palatini theory with cosmological constant
Creators: name: Escalante, Alberto
name: Tzompantzi, Omar Rodríguez
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: A pure Dirac's framework for 3D Palatini's theory with cosmological constant is performed. By considering the complete phase space, we find out the full structure of the constraints, and their corresponding algebra is computed explicitly. We report that in order to obtain a well defined algebra among the constraints, the gauge group must be $SO(2,1)$. In addition, we obtain the extended action, the extended Hamiltonian, the fundamental gauge symmetry, and the Dirac brackets of the theory. Finally, we compare our results with those reported in the literature.
Bosonic thermoelectric transport and breakdown of universality
Creators: name: Rancon, A.
name: Chin, Cheng
name: Levin, K.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: In this paper we compare Bose transport in normal phase atomic gases with its counterpart in Fermi gases, illustrating the non-universality of two dimensional bosonic transport associated with different dissipation mechanisms. Near the superfluid transition temperature $T_c$, a striking similarity between the fermionic and bosonic transport emerges because super-conducting(fluid) fluctuation transport for Fermi gases is dominated by the bosonic, Cooper pair component. As in fluctuation theory, one finds that the Seebeck coefficient changes sign at $T_c$ and the Lorenz number approaches zero at $T_c$. Our findings appear semi-quantitatively consistent with recent Bose gas experiments.
description: v3: longer version 8 pages, 3 figures
Initiation and blocking of the action potential in the axon in weak ultrasonic or microwave fields
Creators: name: Shneider, M. N.
name: Pekker, M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: In this paper, we analyze the effect of the redistribution of the transmembrane ion channels in the axon caused by longitudinal acoustic vibrations of the membrane. These oscillations can be excited by an external source of ultrasound and weak microwave radiation interacting with the charges sitting on the surface of the lipid membrane. It is shown, using the Hodgkin-Huxley model of the axon, that the density redistribution of transmembrane sodium channels may reduce the threshold of the action potential, up to its spontaneous initiation. At the significant redistribution of sodium channels in membrane, the rarefaction zones of the transmembrane channels density are formed, blocking the propagation of the action potential. Blocking the action potential propagation along the axon is shown to cause anestesia in the example case of a squid axon. Various approaches to experimental observation of the effects considered in this paper are discussed.
Bioguided screening and LC-HRMS for identification of toxins and other metabolites of interest produced by the dinoflagellates Gambierdiscus and Fukuyoa
Creators: name: Pisapia, Francesco
Publisher: name: Zenodo
Year: 2017
Subjects: Ciguatera
Gambierdiscus
Fukuyoa
ciguatoxins
maitotoxins
bioguided fractionation
LC-HRMS

description: Bioguided screening and LC-HRMS are analytical techniques used to identify toxins and other metabolites produced by the dinoflagellates Gambierdiscus and Fukuyoa. These microorganisms are known to produce toxins that can accumulate in marine food chains and cause illness in humans who consume contaminated seafood. Bioguided screening involves using bioassays to identify fractions of a sample that contain bioactive compounds. LC-HRMS, on the other hand, is a highly sensitive and selective analytical technique that separates and identifies compounds in a sample based on their mass-to-charge ratio. Together, these techniques can be used to identify specific toxins and other metabolites produced by Gambierdiscus and Fukuyoa. This information can be used to develop methods for detecting and monitoring these organisms in the environment, as well as to develop strategies for mitigating the risks associated with their toxin production.
Non-markovian polariton dynamics in organic strong coupling
Creators: name: Canaguier-Durand, Antoine
name: Genet, Cyriaque
name: Lambrecht, Astrid
name: Ebbesen, Thomas W.
name: Reynaud, Serge
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Strongly coupled organic systems are characterized by unusually large Rabi splittings, even in the vacuum state. They show the counter-intuitive feature of a lifetime of the lower polariton state longer than for all other excited states. Here we build up a new theoretical framework to understand the dynamics of such coupled system. In particular, we show that the non-Markovian character of the relaxation of the dressed organic system explains the long lifetime of the lower polariton state.
description: Expanded version: 6 pages, 4 figures
Quantum limits on post-selected, probabilistic quantum metrology
Creators: name: Combes, Joshua
name: Ferrie, Christopher
name: Jiang, Zhang
name: Caves, Carlton M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Probabilistic metrology attempts to improve parameter estimation by occasionally reporting an excellent estimate and the rest of the time either guessing or doing nothing at all. Here we show that probabilistic metrology can never improve quantum limits on estimation of a single parameter, both on average and asymptotically in number of trials, if performance is judged relative to mean-square estimation error. We extend the result by showing that for a finite number of trials, the probability of obtaining better estimates using probabilistic metrology, as measured by mean-square error, decreases exponentially with the number of trials. To be tight, the performance bounds we derive require that likelihood functions be approximately normal, which in turn depends on how rapidly specific distributions converge to a normal distribution with number of trials.
description: V1:8 pages, 1 figure. V2: 9 pages, 1 figure, revised text. V3: 11 pages, 1 figure, revised text; V4 published version, revised title ;-)
Inputs for percomorph CONDEL screen
Creators: name: Chen, Heidi I.
name: Turakhia, Yatish
name: Bejerano, Gill
name: Kingsley, David M.
Publisher: name: Zenodo
Year: 2023
Subjects: comparative genomics
percomorph fish
transcriptional regulation
evolutionary biology
non-coding DNA

description: Associated manuscript Whole-genome comparisons identify repeated regulatory changes underlying convergent appendage evolution in diverse fish lineages BioRxiv Preprint: https://doi.org/10.1101/2023.01.30.526059 Abstract Fins are major functional appendages of fish that have been repeatedly modified in different lineages. To search for genomic changes underlying natural fin diversity, we compared the genomes of 36 wild fish species that either have complete or reduced pelvic and caudal fins. We identify 1,614 genomic regions that are well-conserved in fin-complete species but missing from multiple fin-reduced lineages. Recurrent deletions of conserved sequences (CONDELs) in wild fin-reduced species are enriched for functions related to appendage development, suggesting that convergent fin reduction at the organismal level is associated with repeated genomic deletions near fin-appendage development genes. We used sequencing and functional enhancer assays to confirm that PelA, a Pitx1 enhancer previously linked to recurrent pelvic loss in sticklebacks, has also been independently deleted and may have contributed to the fin morphology in distantly related pelvic-reduced species. We also identify a novel enhancer that is conserved in the majority of percomorphs, drives caudal fin expression in transgenic stickleback, is missing in tetraodontiform, syngnathid, and synbranchid species with caudal fin reduction, and which alters caudal fin development when targeted by genome editing. Our study illustrates a general strategy for mapping phenotypes to genotypes across a tree of vertebrate species, and highlights notable new examples of regulatory genomic hotspots that have been used to evolve recurrent phenotypes during 100 million years of fish evolution. File information Here, we provide input and intermediate files for recreating the percomorph CONDEL screen described above, using the code and instructions provided at this repository: https://github.com/bejerano-lab/percomorphCONDELs
Macroscopic State Interferometry Over Large Distances Using State Discrimination
Creators: name: Kirby, B. T.
name: Franson, J. D.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The propagation of macroscopic entangled states over large distances in the presence of loss is of fundamental interest and may have practical applications as well. Here we describe two different techniques in which state discrimination can be used to violate Bell's inequality with macroscopic phase-entangled coherent states. We find that Bell's inequality can be violated by these macroscopic states over a distance of approximately 400 km in commercially-available optical fibers.
description: 8 pages, 5 figures
Non-equilibrium steady state and induced currents of a mesoscopically-glassy system: interplay of resistor-network theory and Sinai physics
Creators: name: Hurowitz, Daniel
name: Rahav, Saar
name: Cohen, Doron
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: We introduce an explicit solution for the non-equilibrium steady state (NESS) of a ring that is coupled to a thermal bath, and is driven by an external hot source with log-wide distribution of couplings. Having time scales that stretch over several decades is similar to glassy systems. Consequently there is a wide range of driving intensities where the NESS is like that of a random walker in a biased Brownian landscape. We investigate the resulting statistics of the induced current $I$. For a single ring we discuss how $sign(I)$ fluctuates as the intensity of the driving is increased, while for an ensemble of rings we highlight the fingerprints of Sinai physics on the $abs(I)$ distribution.
description: 9 pages, 8 figures, proofed published version
On the Listsize Capacity with Feedback
Creators: name: Bunte, Christoph
name: Lapidoth, Amos
Publisher: name: arXiv
Year: 2013
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: The listsize capacity of a discrete memoryless channel is the largest transmission rate for which the expectation---or, more generally, the $ρ$-th moment---of the number of messages that could have produced the output of the channel approaches one as the blocklength tends to infinity. We show that for channels with feedback this rate is upper-bounded by the maximum of Gallager's $E_0$ function divided by $ρ$, and that equality holds when the zero-error capacity of the channel is positive. To establish this inequality we prove that feedback does not increase the cutoff rate. Relationships to other notions of channel capacity are explored.
description: 17 pages. Fixed some typos; minor changes in the presentation. Published in the IEEE Transactions on Information Theory. Presented in part at the 2013 IEEE Information Theory Workshop
Fourier-Mukai and autoduality for compactified Jacobians II
Creators: name: Melo, Margarida
name: Rapagnetta, Antontio
name: Viviani, Filippo
Publisher: name: arXiv
Year: 2013
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14H40, 14H20, 14D20, 14F05, 14B07

description: To every reduced (projective) curve X with planar singularities one can associate many fine compactified Jacobians, depending on the choice of a polarization on X, which are birational (possibly non-isomorphic) Calabi-Yau projective varieties with locally complete intersection singularities. We define a Poincare' sheaf on the product of any two (possibly equal) fine compactified Jacobians of X and show that the integral transform with kernel the Poincare' sheaf is an equivalence of their derived categories. In particular, any two fine compactified Jacobians are derived equivalent. When applied to the same fine compactified Jacobian, one gets a Fourier-Mukai autoequivalence, which generalizes the classical result of Mukai for Jacobians of smooth curves (or more generally abelian varieties) and of Arinkin for compactified Jacobians of integral curves, thus providing further evidence for the classical limit of the geometric Langlands conjecture (as formulated by R. Donagi and T. Pantev). As a corollary of our main result, we prove an autoduality result for fine compactified Jacobians: there is a natural equivariant open embedding of the connected component of the scheme parametrizing rank-1 torsion-free sheaves on X into the connected component of the algebraic space parametrizing rank-1 torsion-free sheaves on a given fine compactified Jacobian of X.
description: 35 pages. Final version, to appear in Geometry & Topology
Querying the Guarded Fragment
Creators: name: Bárány, Vince
name: Gottlob, Georg
name: Otto, Martin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Databases (cs.DB)
subject: FOS: Computer and information sciences

description: Evaluating a Boolean conjunctive query Q against a guarded first-order theory F is equivalent to checking whether "F and not Q" is unsatisfiable. This problem is relevant to the areas of database theory and description logic. Since Q may not be guarded, well known results about the decidability, complexity, and finite-model property of the guarded fragment do not obviously carry over to conjunctive query answering over guarded theories, and had been left open in general. By investigating finite guarded bisimilar covers of hypergraphs and relational structures, and by substantially generalising Rosati's finite chase, we prove for guarded theories F and (unions of) conjunctive queries Q that (i) Q is true in each model of F iff Q is true in each finite model of F and (ii) determining whether F implies Q is 2EXPTIME-complete. We further show the following results: (iii) the existence of polynomial-size conformal covers of arbitrary hypergraphs; (iv) a new proof of the finite model property of the clique-guarded fragment; (v) the small model property of the guarded fragment with optimal bounds; (vi) a polynomial-time solution to the canonisation problem modulo guarded bisimulation, which yields (vii) a capturing result for guarded bisimulation invariant PTIME.
description: This is an improved and extended version of the paper of the same title presented at LICS 2010
The influence of mental toughness on responses to feedback in snooker: A real-time examination
Creators: name: Welsh, James C.
name: Dewhurst, Stephen A.
name: Perry, John
Publisher: name: University of Limerick
Year: 2023
Subjects: subject: Physical sciences
subject: FOS: Physical sciences

description: Two experiments investigated whether mental toughness (MT) is associated with the ability to respond to and/or overcome unwanted information during real-time sport performance. Participants were male snooker players ranging from club to professional level, and MT was measured using the MTQ48 (Clough et al., 2002). In experiment 1, players performed five break-off shots and received deceptive feedback (either positive or negative) from the researcher about their performance relative to other players. Then they performed another five break-offs. Results showed a significant decline in performance following feedback, but no interaction with the nature of feedback or MT variables. In experiment 2, feedback was delivered by a coach and yielded a significant effect on performance. Specifically, negative feedback improved performance while positive feedback impaired performance. The Life Control subscale of the MTQ48 was a significant covariate. The results suggest that negative feedback, delivered constructively by a respected figure, may act as a catalyst for performance enhancement in snooker and that this is moderated by MT.
Noise and information transmission in promoters with multiple internal states
Creators: name: Rieckh, Georg
name: Tkačik, Gašper
Publisher: name: arXiv
Year: 2013
Subjects: subject: Molecular Networks (q-bio.MN)
subject: FOS: Biological sciences

description: Based on the measurements of noise in gene expression performed during the last decade, it has become customary to think of gene regulation in terms of a two-state model, where the promoter of a gene can stochastically switch between an ON and an OFF state. As experiments are becoming increasingly precise and the deviations from the two-state model start to be observable, we ask about the experimental signatures of complex multi-state promoters, as well as the functional consequences of this additional complexity. In detail, we (i) extend the calculations for noise in gene expression to promoters described by state transition diagrams with multiple states, (ii) systematically compute the experimentally accessible noise characteristics for these complex promoters, and (iii) use information theory to evaluate the channel capacities of complex promoter architectures and compare them to the baseline provided by the two-state model. We find that adding internal states to the promoter generically decreases channel capacity, except in certain cases, three of which (cooperativity, dual-role regulation, promoter cycling) we analyze in detail.
description: 16 pages, 9 figures
On differential characteristic classes
Creators: name: Ho, Man-Ho
Publisher: name: arXiv
Year: 2013
Subjects: subject: K-Theory and Homology (math.KT)
subject: Algebraic Topology (math.AT)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 57R20, 19L50, 53C08

description: In this paper we give explicit formulas of differential characteristic classes of principal $G$-bundles with connections and prove their expected properties. In particular, we obtain explicit formulas for differential Chern classes, differential Pontryagin classes and differential Euler class. Furthermore, we show that the differential Chern class is the unique natural transformation from (Simons-Sullivan) differential $K$-theory to (Cheeger-Simons) differential characters that is compatible with curvature and characteristic class. We also give the explicit formula for the differential Chern class on Freed-Lott differential $K$-theory. Finally we discuss the odd differential Chern classes.
description: 19 pages. Comments are welcome. Final version. Accepted for publication by Journal of the Australian Mathematical Society
MPEC 2023-F87 : DAILY ORBIT UPDATE (2023 March 21)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Mutually interacting Tachyon dark energy with variable $G$ and $Λ$
Creators: name: Sadeghi, J.
name: Khurshudyan, M.
name: Hakobyan, M.
name: Farahani, H.
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we consider Tachyonic scalar field as dark energy with interaction between components in the case of variable $G$ and $Λ$. We assume a flat Universe with specific form of scale factor and study cosmological parameters numerically and graphically. Statefinder analysis also performed as well. In the special choice of interaction parameters we succeed to obtain analytical expression of densities. We find that our model will be stable in the late stage but there is an instability at the early Universe.
description: 17 pages, accepted by Research in Astronomy and Astrophysics (RAA). arXiv admin note: text overlap with arXiv:1402.2592 by other authors
Search for baryon number violation in top-quark decays
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for baryon number violation (BNV) in top-quark decays is performed using pp collisions produced by the LHC at sqrt(s) = 8 TeV. The top-quark decay considered in this search results in one light lepton (muon or electron), two jets, but no neutrino in the final state. Data used for the analysis were collected by the CMS detector and correspond to an integrated luminosity of 19.5 inverse femtobarns. The event selection is optimized for top quarks produced in pairs, with one undergoing the BNV decay and the other the standard model hadronic decay to three jets. No significant excess of events over the expected yield from standard model processes is observed. The upper limits at 95% confidence level on the branching fraction of the BNV top-quark decay are calculated to be 0.0016 and 0.0017 for the muon and the electron channels, respectively. Assuming lepton universality, an upper limit of 0.0015 results from the combination of the two channels. These limits are the first that have been obtained on a BNV process involving the top quark.
description: Replaced with published version. Added journal reference and DOI
Maitotoxin-4, a novel MTX congener produced by Gambierdiscus excentricus
Creators: name: Pisapia, Francesco
name: Sibat Dubois, Manoëlla
name: Herrencknecht, Christine
name: Lhaute, Korian
name: Gaiani, Greta
name: Ferron, Pierre-Jean
name: Fessard, Valérie
name: Roullier, Catherine
name: Fraga, Santiago
name: Nascimento, Silvia
name: Litaker, Richard Wayne
name: Hess, Philipp
Publisher: name: Zenodo
Year: 2017

description: Maitotoxin-4 is a newly discovered congener of the potent marine toxin maitotoxin, which is produced by the dinoflagellate Gambierdiscus excentricus. This toxin could be implicated in ciguatera fish poisoning, a type of foodborne illness that affects people who consume fish contaminated with ciguatoxins. Maitotoxin-4 has a similar chemical structure to maitotoxin, but it has a slightly different molecular weight.
Emission of forward neutrons by 158A GeV indium nuclei in collisions with Al, Cu, Sn and Pb
Creators: name: Karpechev, E. V.
name: Pshenichnov, I. A.
name: Karavicheva, T. L.
name: Kurepin, A. B.
name: Golubeva, M. B.
name: Guber, F. F.
name: Maevskaia, A. I.
name: Reshetin, A. I.
name: Tiflov, V. V.
name: Topilskaya, N. S.
name: Cortese, P.
name: Dellacasa, G.
name: Arnaldi, R.
name: DeMarco, N.
name: Ferretti, A.
name: Gallio, M.
name: Musso, A.
name: Oppedisano, C.
name: Piccotti, A.
name: Scomparin, E.
name: Vercellin, E.
name: Cicalo, C.
name: Puddu, G.
name: Siddi, E.
name: Szymanski, P.
name: Efthymiopoulos, I.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The cross sections of forward emission of one, two and three neutrons by 158A GeV 115In nuclei in collisions with Al, Cu, Sn and Pb targets are reported. The measurements were performed in the framework of the ALICE-LUMI experiment at the SPS facility at CERN. Various corrections accounting for the absorption of beam nuclei and produced neutrons in target material and surrounding air were introduced. The corrected cross section data are compared with the predictions of the RELDIS model for electromagnetic fragmentation of 115In in ultraperipheral collisions, as well as with the results of the abrasion-ablation model for neutron emission in hadronic interactions. The measured neutron emission cross sections well agree with the RELDIS results, with the exception of In-Al collisions where the measured cross sections are larger compared to RELDIS. This is attributed to a relatively large contribution of hadronic fragmentation of In on Al target with respect to electromagnetic fragmentation, on the contrary to similar measurements performed earlier with 30A GeV 208Pb colliding with Al.
description: 14 pages, 9 figures, 11 tables: updates to the paper structure, typos fixed in version 2
Disorderly Pasts: Kinship, Diagnoses, and Remembering in American Indian-US Histories
Creators: name: Burch, Susan
Publisher: name: Middlebury
Year: 2022
Subjects: Psychiatry (incl. psychotherapy)
Global Indigenous studies health and wellbeing
Global Indigenous studies peoples, society and community

description: “Disorderly Pasts” centers on life stories from South Dakota’s Canton Asylum, a federal psychiatric hospital for American Indians. Between 1902 and 1933, the Asylum detained nearly four hundred Indigenous men, women, and children from more than fifty Native nations. Focusing especially on the experiences of Menominee people collectively stolen from their homes in Wisconsin to Canton in November 1917, this article exposes contested understandings of kin, diagnoses, and remembering. Complex relationships between the three concepts also emerge: medical diagnoses were used to undermine Indigenous kinship, and they complicate remembering. At the same time, remembering—recalling and repopulating the past—offers a way to challenge pathological diagnoses and affirm Native self-determination. Motivated by disorder, the desire to “disrupt the systematic functioning or neat arrangement of” historical work, this project unsettles the projected objectivity and commonsense logic of U.S. medical diagnoses and institutionalization. It brings to light the violent entanglement of settler colonialism, racism, ableism, and patriarchy and their impact on Native sovereignty, Indigenous kinship, and remembering. Collaborating with relatives of those incarcerated at Canton, and drawing on decolonizing and disability studies methodologies, this work seeks to generate meaningful historical knowledge and new theoretical strategies and perspectives.
Documents, Ethics, and the Disability Historian
Creators: name: Burch, Susan
Publisher: name: Middlebury
Year: 2022
Subjects: Human rights and justice issues (excl. law)
Epistemology

description: The factors driving research into disability history methodology in its practical dimensions (such as finding and analyzing sources and presenting findings), the cultural values that inform it, and who populates intended audiences all contribute to the invisible infrastructure of historical production. When historians of disability access a rich source of data, they also must ask who created it, who benefited from its preservation, and whose stories are left untold. Sharing knowledge—through preservation and dissemination—equally shapes disability historical work. In all of this, access and accessibility—from built spaces and source types to research aids and scholarly products—remain paramount. Ways to proceed with sensitivity and creativity in the exploration of disabled peoples’ and disability’s pasts are presented from the perspective of the United States.
Transboundary secondary organic aerosol in western Japan indicated by stable carbon isotope ratio of low volatile water-soluble organic carbon and signal at m/z 44 in organic aerosol mass spectra
Creators: name: Irei, Satoshi
name: Takami, Akinori
name: Hayashi, Masahiko
name: Sadanaga, Yasuhiro
name: Hara, Keiichiro
name: Kaneyasu, Naoki
name: Sato, Kei
name: Arakaki, Takemitsu
name: Hatakeyama, Shiro
name: Bandow, Hiroshi
name: Hikida, Toshihide
name: Shimono, Akio
Publisher: name: arXiv
Year: 2013
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: Field studies were conducted in the winter of 2010 at two rural sites and an urban site in western Japan, and filter samples of total suspended particulate matter were collected every 24-h and analyzed for concentration and stable carbon isotope ratio (delta13C) of low volatile water-soluble organic carbon (LV-WSOC). Concentration of major chemical species in fine aerosol (<1.0 micron) was also measured in real time by Aerodyne aerosol mass spectrometers. Oxidation state of organic aerosol was evaluated using the proportion of signal at m/z 44 (fragment ions of carboxyl group) to the sum of all m/z signals of organic mass spectra (f44). Analyses show a high correlation between LV-WSOC and m/z 44 concentrations, suggesting that the LV-WSOC is likely associated with water soluble carboxylic acids in the fine aerosol. Plots of delta13C of LV-WSOC versus f44 exhibit systematic trends at the rural sites and random variation at the urban site. The systematic trends qualitatively agree with a simple binary mixture model of secondary organic aerosol and background LV-WSOC that has delta13C of -17 permil or higher and f44 of approximately 0.06, respectively. Comparison with references suggests that the source of background LV-WSOC is likely biomass burning of C4 plants.
description: The original manuscript has 36 pages with 0 table and 5 figures
Weak Commutation Relations and Eigenvalue Statistics for Products of Rectangular Random Matrices
Creators: name: Ipsen, J. R.
name: Kieburg, M.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the joint probability density of the eigenvalues of a product of rectangular real, complex or quaternion random matrices in a unified way. The random matrices are distributed according to arbitrary probability densities, whose only restriction is the invariance under left and right multiplication by orthogonal, unitary or unitary symplectic matrices, respectively. We show that a product of rectangular matrices is statistically equivalent to a product of square matrices. Hereby we prove a weak commutation relation of the random matrices at finite matrix sizes, which previously have been discussed for infinite matrix size. Moreover we derive the joint probability densities of the eigenvalues. To illustrate our results we apply them to a product of random matrices drawn from Ginibre ensembles and Jacobi ensembles as well as a mixed version thereof. For these weights we show that the product of complex random matrices yield a determinantal point process, while the real and quaternion matrix ensembles correspond to Pfaffian point processes. Our results are visualized by numerical simulations. Furthermore, we present an application to a transport on a closed, disordered chain coupled to a particle bath.
description: 22 pages, 2 figures
Dissipation vs. quadratic nonlinearity: from a priori energy bound to higher-order regularizing effect
Creators: name: Biswas, Animikh
name: Tadmor, Eitan
Publisher: name: arXiv
Year: 2013
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35K55, 35B65, 35Qxx

description: We consider a rather general class of evolutionary PDEs involving dissipation (of possibly fractional order), which competes with quadratic nonlinearities on the regularity of the overall equation. This includes as prototype models, Burgers' equation, the Navier-Stokes equations, the surface quasi-geostrophic equations and the Keller-Segel model for chemotaxis. Here we establish a Petrowsky type parabolic estimate of such equations which entail a precise time decay of higher-order Sobolev norms for this class of equations. To this end, we introduce as a main new tool, an "infinite order energy functional", E(t): = Σ_n α_n t^n |(-Δ)^{nθ/2} u(*,t)|_{H^{β_c}} for appropriate critical regularity index β_c. It captures the regularizing effect of all higher order derivatives of u(*,t), by proving --- for a carefully, problem-dependent choice of weights {α_n}, that E(t) is non-increasing in time.
Overlaps between eigenstates of the XXZ spin-1/2 chain and a class of simple product states
Creators: name: Pozsgay, B.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Exactly Solvable and Integrable Systems (nlin.SI)
subject: FOS: Physical sciences

description: We consider a class of quantum quenches in the spin-1/2 XXZ chain, where the initial state is of a simple product form. Specific examples are the Néel state, the dimer state and the q-deformed dimer state. We compute determinant formulas for finite volume overlaps between the initial state and arbitrary eigenstates of the spin chain Hamiltonian. These results could serve as a basis for calculating the time dependence of correlation functions following the quantum quench.
description: 17 pages, 1 figure, v2: one reference added, v3: minor modification, v4: minor modification, v5: calculation of the determinant formula simplified and a note added, v6: references updated
The reduced knot Floer complex
Creators: name: Krcatovich, David
Publisher: name: arXiv
Year: 2013
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 57M27

description: We define a "reduced" version of the knot Floer complex $CFK^-(K)$, and show that it behaves well under connected sums and retains enough information to compute Heegaard Floer $d$-invariants of manifolds arising as surgeries on the knot $K$. As an application to connected sums, we prove that if a knot in the three-sphere admits an $L$-space surgery, it must be a prime knot. As an application of the computation of $d$-invariants, we show that the Alexander polynomial is a concordance invariant within the class of $L$-space knots, and show the four-genus bound given by the $d$-invariant of +1-surgery is independent of the genus bounds given by the Ozsváth-Szabó $τ$ invariant, the knot signature and the Rasmussen $s$ invariant.
description: 41 pages, 14 figures; changed formatting, updated references, added some clarifying remarks, results unchanged
Canard-like phenomena in piecewise-smooth Van der Pol systems
Creators: name: Roberts, Andrew
name: Glendinning, Paul
Publisher: name: arXiv
Year: 2013
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: We show that a nonlinear, piecewise-smooth, planar dynamical system can exhibit canard phenomena. Canard solutions and explosion in nonlinear, piecewise-smooth systems can be qualitatively more similar to the phenomena in smooth systems than piecewise-linear systems, since the nonlinearity allows for canards to transition from small cycles to canards ``with heads." The canards are born of a bifurcation that occurs as the slow-nullcline coincides with the splitting manifold. However, there are conditions under which this bifurcation leads to a phenomenon called super-explosion, the instantaneous transition from a globally attracting periodic orbit to relaxations oscillations. Also, we demonstrate that the bifurcation---whether leading to canards or super-explosion---can be subcritical.
description: 17 pages, 11 figures
On some determinants with Legendre symbol entries
Creators: name: Sun, Zhi-Wei
Publisher: name: arXiv
Year: 2013
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11C20, 15A15, 11A07, 11R11

description: In this paper we mainly focus on some determinants with Legendre symbol entries. Let $p$ be an odd prime and let $(\frac{\cdot}p)$ be the Legendre symbol. We show that $(\frac{-S(d,p)}p)=1$ for any $d\in\mathbb Z$ with $(\frac dp)=1$, and that $$\left(\frac{W_p}p\right)=\begin{cases}(-1)^{|\{0
description: 22 pages, final published version
Existence and regularity of time-periodic solutions to the three-dimensional Navier-Stokes equations
Creators: name: Kyed, Mads
Publisher: name: arXiv
Year: 2013
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: 35Q30, 35B10, 76D05, 76D03

description: Existence, uniqueness, and regularity of time-periodic solutions to the Navier-Stokes equations in the three-dimensional whole-space are investigated. We consider the Navier-Stokes equations with a non-zero drift term corresponding to the physical model of a fluid flow around a body that moves with a non-zero constant velocity. Existence of a strong time-periodic solution is shown for small time-periodic data. It is further shown that this solution is unique in a large class of weak solutions that can be considered physically reasonable. Finally, we establish regularity properties for any strong solution regardless of its size.
description: 34 pages
In search of the elusive bioactive compounds of Gambierdiscus spp.
Creators: name: Pisapia, Francesco
Publisher: name: Zenodo
Year: 2016

description: Gambierdiscus is a genus of marine dinoflagellates that produce toxins that can accumulate in seafood and cause ciguatera fish poisoning in humans. While Ciguatera illness is well-studied, less is known about the bioactive compounds produced by Gambierdiscus that are implicated in the poisoning and that may have potential pharmaceutical or biotechnological applications. In recent years, there has been growing interest in discovering and characterizing these elusive bioactive compounds, which could have significant implications for drug discovery and other areas of research. However, the identification and isolation of these compounds is challenging due to the complex chemistry of Gambierdiscus and the low concentrations of the compounds in the organism. During an oral communication, Francesco Pisapia discussed a variety of analytical and bioassay techniques, such as bioguided screening and LC-MS, which are used to isolate and identify bioactive compounds from Gambierdiscus. The search for these elusive compounds is an ongoing area of research with the potential to uncover new therapeutic agents and advance our understanding of the chemical diversity of marine microorganisms.
Reply to Commentaries on 'An Evolutionary Framework for Cultural Change: Selectionism versus Communal Exchange'
Creators: name: Gabora, Liane
Publisher: name: arXiv
Year: 2013
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: The commentators have brought a wealth of new perspectives to the question of how culture evolves. Each of their diverse disciplines--ranging from psychology to biology to anthropology to economics to engineering--has a valuable contribution to make to our understanding of this complex, multifaceted topic. Though the vast majority of their comments were supportive of my approach, it is natural that a reply such as this focus on points where my views differ from that of the commentators. ... I conclude by saying that I am grateful to the commentators for their diverse perspectives and insights, their overall support for the project, and provocative ideas for where to go from here. Clearly there are many fascinating avenues to explore as we move forward on our quest to understand how culture evolves.
description: 8 pages; this is a reply to commentaries on q-bio.PE/0773336
Analytical estimates of the locations of phase transition points in the ground state for the bimodal Ising spin glass model in two dimensions
Creators: name: Yamaguchi, Chiaki
Publisher: name: arXiv
Year: 2013
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We analytically estimate the locations of phase transition points in the ground state for the $\pm J$ random bond Ising model with asymmetric bond distributions on the square lattice. We propose and study the percolation transitions for two types of bond shared by two non-frustrated plaquettes. The present method indirectly treats the sizes of clusters of correlated spins for the ferromagnetic and spin glass orders. We find two transition points. The first transition point is the phase transition point for the ferromagnetic order, and the location is obtained as $p_c^{(1)} \approx 0.895 \, 399 \, 54$ as the solution of $[p^2 + 3 (1-p)^2 ]^2 \, p^3 - \frac{1}{2} = 0$. The second transition point is the phase transition point for the spin glass order, and the location is obtained as $p_c^{(2)} = \frac{1}{4} [2 + \sqrt{2 (\sqrt{5} - 1)}] \approx 0.893 \, 075 \, 69$. Here, $p$ is the ferromagnetic bond concentration, and $1 - p$ is the antiferromagnetic bond concentration. The obtained locations are reasonably close to the previously estimated locations. This study suggests the presence of the intermediate phase between $p_c^{(1)}$ and $p_c^{(2)}$; however, since the present method produces remarkable values but has no mathematical proof for accuracy yet, no conclusions are drawn in this article about the presence of the intermediate phase.
description: 10 pages, 5 figures. v3: this is the final version