cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Expression of the neuroprotective protein aryl hydrocarbon receptor nuclear translocator 2 correlates with neuronal stress and disability in models of multiple sclerosis
Creators: name: Rahim, Tissa
name: Becquart, Pierre
name: Baeva, Maria-Elizabeth
name: Quandt, Jacqueline
Publisher: name: BioMed Central
Year: 2018

description: Background: Axonal degeneration and neuronal loss have been described as the major causes of irreversible clinical disability in multiple sclerosis (MS). The aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) protein has been associated with neuroprotection in models of ischemia and neuronal responses to stressors. Methods: To characterize its potential to influence inflammatory neurodegeneration, we examined ARNT2 expression in the experimental autoimmune encephalomyelitis (EAE) model of MS and characterized mediators that influence ARNT2 expression as well as plausible partners and targets. Results: Arnt2 message and protein levels dropped significantly in EAE spinal cords as disease developed and were lowest at peak disability. ARNT2 expression is prominent in neuronal cell bodies within the gray matter with some staining in glial fibrillary acidic protein (GFAP)+ astrocytes in healthy animals. At peak disease, ARNT2 expression is reduced by 20–50% in gray matter neurons compared to healthy controls. ARNT2 intensity in neurons throughout the EAE spinal cord correlated inversely with the degree of immune cell infiltration (r = − 0.5085, p < 0.01) and axonal damage identified with SMI32 staining (r = − 0.376, p = 0.032). To understand the relationship between ARNT2 expression and neuronal health, we exposed enriched cortical cultures of neurons to hydrogen peroxide (H2O2) to mimic oxidative stress. H2O2 at lower doses rapidly increased ARNT2 protein levels which returned to baseline within 3–4 h. Exposure to higher doses of H2O2) dropped ARNT2 levels below baseline, preceding cytotoxicity measured by morphological changes and lactate dehydrogenase release from cells. Decreases in ARNT2 secondary to staurosporine and H2O2 preceded increases in cleaved caspase 3 and associated apoptosis. We also examined expression of neuronal pas 4 (Npas4), whose heterodimerization with ARNT2 drives expression of the neurotrophic factor brain-derived neurotrophic factor (Bdnf). Like ARNT2, Npas4 levels also decline at the onset of EAE and are linked to decreases in Bdnf. In vitro, H2O2 exposure drives Npas4 expression that is tied to increases in Bdnf. Conclusion: Our data support ARNT2 as a neuronal transcription factor whose sustained expression is linked to neuronal and axonal health, protection that may primarily be driven through its partnering with Npas4 to influence BDNF expression.
Coherent structures in uniformly sheared turbulence
Creators: name: Vanderwel, Christina M
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Engineering, Mechanical.

description: Uniformly sheared turbulent flow with a turbulence Reynolds number Relambda in the range from 80 to 100 has been generated in a water tunnel and its instantaneous structure has been examined using flow visualization, laser Doppler velocimetry and particle image velocimetry. The flow was found to consist of regions with nearly uniform velocity, which were separated by relatively strong shear layers containing large vortices. The concentration of vortices and the probability distribution functions of their directions of rotation, strengths, sizes and shapes in three characteristic planes of the flow have been determined. These results, as well as hydrogen bubble visualisations and high-speed scans of injected dye patterns, support the hypothesis that horseshoe-shaped vortices are prevalent in this flow.
Supplementary document for Investigating dynamic behavior of a high-power thin-disk laser resonator using moire technique - 4709923.pdf
Creators: name: Daemi, Mohammad Hossein
name: Rasouli, Saifollah
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Galactic Astronomy
Complex Physical Systems
Nanomaterials

description: The paper’s high-resolution figures and an additional figure that presents a schematic representation of the use of Talbot interferometer as a wavefront sensor.
Markov chain models and stochastic differential equations.
Creators: name: Fitch, Frank H.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1969
Subjects: subject: Engineering, Electronics and Electrical.

description: The trajectories of motion of dynamic systems subject to Gaussian White Noise inputs have in the past been studied by application of the Fokker-Planck-Kolmogorov partial differential equation. This thesis sets forth an alternate approach where step functions are used to simulate Gaussian White Noise inputs over intervals of time. Systems considered are of the class dy&d1; =f&d1;1 y&d1;, u&d1;,t dt+f&d1;2 y&d1; ,u&d1;,t n&d1; tdt where n¯(t) is a Gaussian White Noise vector, y¯(t) is a state vector, u(t) is a piecewise continuous vector function and f¯ 1, f¯2 are continuous vector functions which may be linear or nonlinear. A mathematical procedure is formulated to obtain a Markov Chain model for {y¯(t)} or any of the individual components {y1(t)}, {y 2(t)}, ... , {yr(t)} as a separate and distinct stochastic processes. Finally, a stability test is developed to predict whether the range of values of {y¯(t)} is finite in the Euclidean space Rr for all t > 0.
Phase space evolution and discontinuous Schrödinger waves
Creators: name: Sadurní, E
Publisher: name: Universität Ulm
Year: 2012
Subjects: subject: DDC 530 / Physics
subject: Discontinuous functions
subject: Wavelets (Mathematics)
subject: Wavelet-Analyse

description: The problem of Schrödinger propagation of a discontinuous wavefunction – diffraction in time – is studied under a new light. It is shown that the evolution map in phase space induces a set of affine transformations on discontinuous wavepackets, generating expansions similar to those of wavelet analysis. Such transformations are identified as the cause for the infinitesimal details in diffraction patterns. A simple case of an evolution map, such as SL(2) in a two-dimensional phase space, is shown to produce an infinite set of space-time trajectories of constant probability. The trajectories emerge from a breaking point of the initial wave.
Real-time impedance monitoring of 3D cell cultures
Creators: name: De Leon Vergara, Sorel E.
Publisher: name: Swinburne
Year: 2024

description: Two-dimensional cell cultures have been the gold standard for first trials of drug discovery and cell behaviour studies. However simple, there is increasing research showing that the cells behave different when grown on a flat surface. To overcome this gap in research, scientists have developed three-dimensional cell culture models. Even though this technique is becoming more popular with scientists there are not enough standardise sensors to know in real time what is happening with the cells. This thesis explores the use of impedance spectroscopy for monitoring these three dimensional culture models in real time; the technique measures the electrical properties of the cells to understand their health status. This thesis helped with the progress in the understanding of the electrical properties of these complex three-dimensional models.
Identifying emerging environmental concerns from long-chain chlorinated paraffins towards German ecosystems
Creators: name: Yuan, Bo
name: Koschorreck, Jan
name: Rüdel, Heinz
name: De Wit, Cynthia A.
Publisher: name: My University
Year: 2022
Subjects: Bioakkumulation

description: Germany is one of several major European producers of chlorinated paraffins (CPs). This study showed that not only the legacy short-chain products (SCCPs, C10-13), but also the current-use medium- and long-chain products (MCCPs, C14-17; LCCPs, C>17) as well as the very-short-chain impurities (vSCCPs, C<10) are ubiquitous in the 72 samples collected from the coastal, terrestrial, and freshwater ecosystems across the country. The concentrations of LCCPs surpassed those of the other CPs in 40% of the biota samples. Archived bream samples collected downstream of a CP-manufacturing factory showed decreasing temporal trends of (v)SCCPs and relatively constant levels of MCCPs from 1995 to 2019; however, the overall levels of LCCPs have increased by 290%, reflecting the impact of chemical regulation policies on changes in CP production. A visualization algorithm was developed for integrating CP results from various matrices to illustrate spatial tendencies of CP pollution. Higher levels of (v)SCCPs were indicated in the former West Germany region, while MCCP and LCCP concentrations did not seem to differ between former East and West Germany, suggesting relatively equal production and use of these chemicals after the German Reunification. The results provide an early warning signal of environmental concerns from LCCPs on the eve of their booming global production and use. © 2021 The Author(s).
Supplementary document for Investigating dynamic behavior of a high-power thin-disk laser resonator using moire technique - 4709923.pdf
Creators: name: Daemi, Mohammad Hossein
name: Rasouli, Saifollah
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Galactic Astronomy
Complex Physical Systems
Nanomaterials

description: The paper’s high-resolution figures and an additional figure that presents a schematic representation of the use of Talbot interferometer as a wavefront sensor.
Transport and retention of differently coated CeO2 nanoparticles in saturated sediment columns under laboratory and near-natural conditions
Creators: name: Degenkolb, Laura
name: Dippon-Deissler, Urs
name: Klitzke, Sondra
name: Pabst, Silke
Publisher: name: My University
Year: 2019
Subjects: Oberflächengewässer

description: Where surface-functionalized engineered nanoparticles (NP) occur in drinking water catchments, understanding their transport within and between environmental compartments such as surface water and groundwater is crucial for risk assessment of drinking water resources. The transport of NP is mainly controlled by (i) their surface properties, (ii) water chemistry, and (iii) surface properties of the stationary phase. Therefore, functionalization of NP surfaces by organic coatings may change their fate in the environment. In laboratory columns, we compared the mobility of CeO2 NP coated by the synthetic polymer polyacrylic acid (PAA) with CeO2 NP coated by natural organic matter (NOM) and humic acid (HA), respectively. The effect of ionic strength on transport in sand columns was investigated using deionized (DI) water and natural surface water with 2.2 mM Ca2+ (soft) and 4.5 mM Ca2+ (hard), respectively. Furthermore, the relevance of these findings was validated in a near-natural bank filtration experiment using HA-CeO2 NP. PAA-CeO2 NP were mobile under all tested water conditions, showing a breakthrough of 60% irrespective of the Ca2+ concentration. In contrast, NOM-CeO2 NP showed a lower mobility with a breakthrough of 27% in DI and < 10% in soft surface water. In hard surface water, NOM-CeO2 NP were completely retained in the first 2 cm of the column. The transport of HA-CeO2 NP in laboratory columns in soft surface water was lower compared to NOM-CeO2 NP with a strong accumulation of CeO2 NP in the first few centimeters of the column. Natural coatings were generally less stabilizing and more susceptible to increasing Ca2+ concentrations than the synthetic coating. The outdoor column experiment confirmed the low mobility of HA-CeO2 NP under more complex environmental conditions. From our experiments, we conclude that the synthetic polymer is more efficient in facilitating NP transport than natural coatings and hence, CeO2 NP mobility may vary significantly depending on the surface coating. © The Author(s) 2019
The Beliefs about Voices Questionnaire – Revised: A factor structure from 450 participants
Creators: name: Strauss, Clara
name: Hugdahl, Kenneth
name: Waters, Flavie
name: Hayward, Mark
name: Bless, Josef J.
name: Falkenberg, Liv E.
name: Kråkvik, Bodil
name: Asbjørnsen, Arve Egil
name: Johnsen, Erik
name: Sinkeviciute, Igne
name: Kroken, Rune A.
name: Løberg, Else Marie
name: Thomas, Neil
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 520302
subject: Clinical psychology

description: Hallucinated voices are common across psychiatric and non-clinical groups. The predominant cognitive theory about the impact of voices posits that beliefs about voice power (‘Omnipotence’) and voice intent (‘Malevolence’/‘Benevolence’) play a key role in determining emotional and behavioral reactions. The revised Beliefs about Voices Questionnaire (BAVQ-R) was designed to assess these constructs, together with two styles of responding (Engagement and Resistance). The BAVQ-R is widely used in clinical and research settings, yet it has not received validation of its constructs and factor structure. This study examined the factor structure of the BAVQ-R by combining datasets from five study centers, comprising 450 participants (belief constructs) and 269 participants (response styles), and using confirmatory and exploratory factor analysis. Findings failed to support a three factor belief model, instead showing a two-factor structure (‘Persecutory beliefs’ combining Omnipotence and Malevolence constructs, and a Benevolent construct). Emotional and behavioral items did not separate. Overall, results showed that (i) a two-factor model of beliefs (Persecutory and Benevolent beliefs) provides a better fit to the data than a three-factor model, and (ii) emotional and behavioral modes of responding items should not be separated. Theoretical implications of this finding are discussed in relation to the research and therapy.
Diversification of early eukaryotes – evidence from the Mesoproterozoic Lakhanda Lagerstätt (Siberia, Russia)
Creators: name: Shuvalova, Julia V.
Publisher: name: Swinburne
Year: 2024

description: This project revises the systematic affinity of fossil eukaryotes from the ~1.03 Ga Lakhanda Lagerstätte based on the up-to-date knowledge of early eukaryotes in paleontological record. Critical morphological and biogeochemical analyses of the Lakhanda Lagerstätte eukaryotic archive were undertaken to determine the value of these fossils in the phylogenetic reconstruction of the early branching eukaryotic lineages. In summary, the Upper Mesoproterozoic Lakhanda Lagerstätte of southeastern Siberia contains crucial information about diversity and functioning of transitional Meso- Neoproterozoic ecosystems, which may assist in fundamental reconstructions of early eukaryote evolution.
La répression des crimes internationaux devant les tribunaux internes
Creators: name: Manirakiza, Pacifique
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Law.
subject: Political Science, International Law and Relations.

description: Le phénomène criminel est inhérent à toute société. Actuellement, la criminalité internationale est devenue un phénomène fréquent et très préoccupant pour la communauté internationale dans son ensemble. En effet, la commission des crimes internationaux les plus graves comme le génocide, les crimes de guerre et les crimes contre l'humanité porte gravement atteinte aux valeurs communes jugées fondamentales pour l'humanité entière. De par la complexité de ces à ces graves de violence et l'extrême barbarie qui entoure leur commission, la communauté internationale a mis en place des mécanismes juridiques et institutionnels de protéction estimés efficaces pour juguler ce phénomène afin d'en prévenir la récurrence. Ainsi, des juridictions pénales internationales ont été créées où sont sur le point de l'être. Cependant, en raison de l'ampleur du phénomène criminel international, les juridictions internationales ne sauraient, à elles seules, venir à bout de l'impunité qui en résulte. Les juridictions répréssives étatiques sont donc interpellées pour prêter main-forte aux tribunaux internationaux dans la lutte contre l'impunité du crime international. En vertu du droit pénal international, les tribunaux internés peuvent intervenir sous plusieurs titres de compétence en l'occurrence la territorialité, la personnalité et l'universalité. Néanmoins, quoique juridiquement habilitées par le droit international à assurer la répression des crimes internationaux, certaines juridictions étatiques font face à plusieurs obstacles et contraintes de plusieurs ordres qu'elles deviennent incapables où se montrent moins enthousiastes pour engager de veritables poursuites pénales pour crimes internationaux. Il s'agit en l'occurrence des tribunaux des États qui sortent d'un conflit arme, d'une crise humanitaire ou d'une dictature qui ont rendu l'appareil judiciaire ineffectif et/ou inefficace. L'exemple du Rwanda est à cet égard très éloquent. Dans ce cas, la communauté internationale pour le compte de laquelle la justice est rendue à le devoir de venir en aide à ces appareils judiciaires étatiques afin d'en renforcer la capacité pour leur permettre de mieux assumer convenablement cette noble mission d'administration interne de la justice pénale internationale. Une telle intervention de la communauté internationale aboutit à l'internationalisation de la fonction judiciaire qui se traduirait par la mise en place de juridictions pénales internationalisées spécifiquement chargées du traitement judiciaire du génocide, des crimes de guerre et des crimes contre l'humanité. (Abstract shortened by UMI.)
Histone deacetylase inhibitors synergizes with catalytic inhibitors of EZH2 to exhibit antitumor activity in small cell carcinoma of the ovary, hypercalcemic type
Creators: name: Wang, Yemin
name: Chen, Shary Yuting
name: Colborne, Shane
name: Lambert, Galen
name: Shin, Chae Young
name: Dos Santos, Nancy
name: Orlando, Krystal A.
name: Lang, Jessica D
name: Hendricks, William P.D.
name: Marcel B., Bally
name: Karnezis, Anthony N.
name: Hass, Ralf
name: Underhill, T M
name: Morin, Gregg B.
name: Trent, Jeffrey M.
name: Weissman, Bernard E.
name: Huntsman, David G.
Publisher: name: The University of British Columbia
Year: 2019

description: Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but extremely lethal malignancy that mainly impacts young women. SCCOHT is characterized by a diploid genome with loss of SMARCA4 and lack of SMARCA2 expression, two mutually exclusive ATPases of the SWI/SNF chromatin-remodeling complex. We and others have identified the histone methyltransferase EZH2 as a promising therapeutic target for SCCOHT, suggesting that SCCOHT cells depend on the alternation of epigenetic pathways for survival. In this study, we found that SCCOHT cells were more sensitive to pan-HDAC inhibitors compared to other ovarian cancer lines or immortalized cell lines tested. Pan-HDAC inhibitors, such as quisinostat, reversed the expression of a group of proteins that were deregulated in SCCOHT cells due to SMARCA4 loss, leading to growth arrest, apoptosis and differentiation in vitro and suppressed tumor growth of xenografted tumors of SCCOHT cells. Moreover, combined treatment of HDAC inhibitors and EZH2 inhibitors at sub-lethal doses synergistically induced histone H3K27 acetylation and target gene expression, leading to rapid induction of apoptosis and growth suppression of SCCOHT cells and xenografted tumors. Therefore, our preclinical study highlighted the therapeutic potential of combined treatment of HDAC inhibitors with EZH2 catalytic inhibitors to treat SCCOHT.
On random reductions from sparse sets to tally sets
Creators: name: Schöning, Uwe
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 004 / Data processing & computer science
subject: Computational complexity

description: We show that every sparse set S can be many-one reduced to an appropriate tally set T by a polynomial-time, randomized reduction (see formal definitions below). Since T is in NP if S is in NP, this result can be used to show that there is a tally set in NP being randomized many-one complete for all sparse sets in NP. This partially answers an open problem posed by Hartmanis and Yesha [Ha].
Supplementary document for Swimming force and behaviour of optically trapped micro-organisms - 4710087.pdf
Creators: name: Armstrong, Declan
name: Stilgoe, Alexander
name: Lenton, Isaac
name: Nieminen, Timo
name: Kashchuk, Anatolii
name: Rubinsztein-Dunlop, Halina
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: subject: Biophysics
subject: Biological Physics
subject: FOS: Biological sciences

description: Revised supplemental .TEX files. Figures used within supplemental file are included within the .zip folder
A non-linear numerical model for stratified tsunami waves and its application
Creators: name: Imteaz, Monzur
name: Imamura, Fumihiko
Publisher: name: Swinburne
Year: 2024

description: A non-linear numerical model is developed for the computation of water level and discharge for the propagation of a unidirectional two-layered tsunami wave. Four governing equations, two for each layer, are derived from Euler’s equations of motion and continuity, assuming a long wave approximation, negligible friction and no interfacial mixing. A numerical model is developed using a staggered Leap-Frog scheme. The developed nonlinear model is compared with an existing validated linear model developed earlier by the author for different non-dimensional wave amplitudes. The significance of non-linear terms is discussed. It is found that for simulations of the interface wave amplitude, the effect of non-linear terms is not significant. However, for the simulation of the top surface, the effect of non-linear terms is significant for higher wave amplitudes, and insignificant for lower wave amplitudes. Developed non-linear numerical model is used for the case of a progressive internal wave in an inclined bay. It is found that the effect of an adverse bottom slipe towards the direction of wave propagation is to amplify the wave. This amplification depends on the steepness of slope as well as the ratio of densities of upper layer fluid to lower layer fluid (α). Amplification increases with slope. For higher values of α, amplification of the top and interface surface decreases, which is reasonable. It is also found that even for a 4 percent density difference between upper layer and lower layer, amplification of the top surface will be twenty times higher than amplification in the non-stratified case. The model can be applied confidently to simulate the basic features of different practical problems, similar to those investigated in this study.
Lower Superoxide Dismutase 2 (SOD2) Protein Content in Mononuclear Cells Is Associated with Better Survival in Patients with Hemodialysis Therapy
Creators: name: Krueger, Katharina
name: Shen, Jianlin
name: Maier, Alexandra
name: Tepel, Martin
name: Scholze, Alexandra
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Mitochondrial superoxide dismutase 2 (SOD2) converts superoxide anions to hydrogen peroxide and oxygen. Human data on SOD2 protein content in chronic kidney disease (CKD) are sparse and mortality data are lacking. We investigated SOD2 protein content in monocytes from patients with hemodialysis therapy (), CKD stage 1–5 (), and healthy controls () using in-cell Western assays. SOD2 protein decreased from CKD stage 1 until stage 4 whereas it increased again in stage 5 with and without hemodialysis. SOD2 gene expression, analyzed by quantitative real-time PCR, was not significantly different between the groups. Elevating cellular superoxide production reduced SOD2 protein content. This effect was abolished by the superoxide dismutase mimetic Tempol. Using gelelectrophoresis and Western blot we did not detect nitrotyrosine modifications of SOD2 in CKD. Finally, in patients with CKD stage 5 with hemodialysis therapy higher than median SOD2 protein content was associated with higher all-cause mortality. In conclusion, SOD2 protein content declined in CKD until stage 4 while SOD2 gene expression did not. Increased cellular superoxide anion production might affect SOD2 protein content. In advanced CKD (stage 5) SOD2 protein content increased again, but higher than median SOD2 protein content in these patients did not confer a survival benefit.
XML based service provisioning in converged voice and data networks
Creators: name: Cetiner, Sertac
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: ACE
subject: Call processing language
subject: DOM
subject: IP telephony
subject: TAO
subject: XML parser
subject: CORBA
subject: Intelligentes Netz
subject: SIP
subject: XML

description: In today’s world, there are mainly two types of communication networks: circuit-switched networks and packet-switched networks. The current telephone networks are mostly based on the circuit-switched networks, whereas the Internet is mainly based on the packet-switched networks, which are also called IP networks. However, there is a strong tendency to combine both of these networks, which points to the direction that the IP networks are going to replace services provided by current telephone networks. This would eventually mean that IP networks might replace the telephone networks, in the future.
title: Diagnóstico diferencial de las lesiones tumorales y seudotumorales en el clivus mediante TC y RM. Una puesta al día.
Creators: name: Paniagua Bravo, Alvaro
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neoplasia
subject: Haematologic diseases
subject: Dysplasias
subject: CT
subject: MR
subject: Conventional radiography
subject: Musculoskeletal bone
subject: Head and neck

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
El objetivo principal es describir la semiología del clivus normal y de varias lesiones que típicamente asientan sobre esta región anatómica.
Se describen las características en TC y RM que se deben conocer para alcanzar un adecuado...
Supplementary document for Swimming force and behaviour of optically trapped micro-organisms - 4710087.pdf
Creators: name: Armstrong, Declan
name: Stilgoe, Alexander
name: Lenton, Isaac
name: Nieminen, Timo
name: Kashchuk, Anatolii
name: Rubinsztein-Dunlop, Halina
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: subject: Biophysics
subject: Biological Physics
subject: FOS: Biological sciences

description: Revised supplemental .TEX files. Figures used within supplemental file are included within the .zip folder
title: Características ecográficas de lesiones dermatológicas
Creators: name: Mendoza Arnau, Inmaculada
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Soft tissues / Skin
subject: Musculoskeletal soft tissue

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
1.Valorar el papel de la ecografía en la valoración de las lesiones cutáneas intentando establecer características de benignidad y malignidad. 2.Describir las ventajas e inconvenientes de la ecografía. 3.Revisar la técnica ecográficay gracias...
Étude de la répartition spatiale du cation Pb dans la végétation forestière au voisinage de l'autoroute 417.
Creators: name: Cardinal, Suzanne.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Agriculture, Forestry and Wildlife.

description: The purpose of this thesis is to explain the spatial diffusion of lead in the forest vegetation along highway 417, around Limoges, Ontario. The analyses of samples taken along both sides of the highway 417 tells us that the wind is the main carrier of particulate lead. Knowing that the predominant winds are from WNW, we conclude that there is a greater concentration of lead north-east of the highway where most of the emanations fall. Lead particles that are carried by the winds settle on the tree foliage and are absorbed in very small quantities by the leaves stomates. The concentration of lead on foliage diminishes gradually with distance from the highway and distilled water will not wash it off. Lead also appears on the tree trunks. There again, the concentration is found to diminish with distance from the highway. The study also reveals that there is no correlation between the concentration of lead on the outside of the tree barks and the inside. Actually, this study cannot explain this phenomenon. (Abstract shortened by UMI.)
title: Paniculitis Mesentérica: ¿es posible diagnosticarla mediante ecografía?
Creators: name: Fernandez Temprano, Zulema
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Inflammation
subject: Education
subject: Ultrasound
subject: Abdomen

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Describir y dar a conocer las características ecográficas de la paniculitis mesentérica.
Es una entidad que se diagnostica cada vez con más frecuencia en la práctica diaria debido al incremento en el empleo de diversas técnicas de imagen tanto...
Connecting massive galaxies to dark matter haloes in BOSS - I. Is galaxy colour a stochastic process in high-mass haloes?
Creators: name: Saito, Shun
name: Leauthaud, Alexie
name: Hearin, Andrew P.
name: Bundy, Kevin
name: Zentner, Andrew R.
name: Behroozi, Peter S.
name: Reid, Beth A.
name: Sinha, Manodeep
name: Coupon, Jean
name: Tinker, Jeremy L.
name: White, Martin
name: Schneider, Donald P.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 5101
subject: Astronomical sciences

description: We use subhalo abundance matching (SHAM) to model the stellar mass function (SMF) and clustering of the Baryon Oscillation Spectroscopic Survey (BOSS) 'CMASS' sample at z ~ 0.5. We introduce a novel method which accounts for the stellar mass incompleteness of CMASS as a function of redshift, and produce CMASS mock catalogues which include selection effects, reproduce the overall SMF, the projected two-point correlation function wp, the CMASS dn/dz, and are made publicly available. We study the effects of assembly bias above collapse mass in the context of 'age matching' and show that these effects are markedly different compared to the ones explored by Hearin et al. at lower stellar masses. We construct two models, one in which galaxy colour is stochastic ('AbM' model) as well as a model which contains assembly bias effects ('AgM' model). By confronting the redshift dependent clustering of CMASS with the predictions from our model, we argue that that galaxy colours are not a stochastic process in high-mass haloes. Our results suggest that the colours of galaxies in high-mass haloes are determined by other halo properties besides halo peak velocity and that assembly bias effects play an important role in determining the clustering properties of this sample.
An automated system for determining psychophysical stereo-threshold to dynamic random dot stimuli
Creators: name: Jedynak, Andreas
name: Schier, Mark
name: Skrandies, Wolfgang
Publisher: name: Swinburne
Year: 2024

description: We describe an approach to the problem of measuring stereoscopic thresholds to images of random dot stereograms. This involves using an Apple Macintosh computer with 640x480-pixel monitor with shutter glasses alternating the view to left and right eyes, while simultaneously changing the horizontal disparity of a pair of images on the screen so that it has ‘depth’. While this approach is not new, the process of generating the images during the operation of the program is novel and eliminates the requirement for massive libraries of images. A second feature is the inclusion of maximum likelihood threshold estimation in the operation of the program, so that psychophysical thresholds can be measured, either in the complete image, or separately in the right and left visual fields. This system is now in operation in Germany and being duplicated in Australia.
Biodiesel Production from High FFA Feedstock Using a Membrane Reactor
Creators: name: Hasswa, Raghda
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Alternative Energy.
subject: Engineering, Chemical.

description: Biodiesel is a renewable source of energy typically produced in a chemical process known as transesterification. The process involves the reaction of an alcohol with vegetable oil or animal fat in the presence of a catalyst to yield mono-alkyl esters (biodiesel) and glycerol as a by-product. The biodiesel market is amongst the fastest growing renewable energy markets and there is a genuine interest in its development from industry and academia. However, there are some challenges that are facing biodiesel and hindering its commercialization. The major ones are production cost and quality. The process must be cost-effective whilst producing biodiesel that meets international standards (ASTM D6751 and EN 14214). The main objectives of this project were to investigate the use of a continuous membrane reactor for the production of biodiesel from waste vegetable oil feedstock with high free fatty acid (FFA) content and to investigate the effect of membrane pore size on the separation of soap and triglycerides in the reactor. This was achieved through the construction and operation of a lab scale continuous membrane reactor. The membrane reactor integrates many procedures such as combining the chemical reaction and the membrane-based separation in the same unit. The biodiesel was produced by base-catalyzed transesterification. Two levels of FFA in the waste vegetable oil feedstock were studied, 4.8 and 10 mass%. Ceramic membranes were used, with membrane pore sizes ranging from 1 to 800 nm. It was found that the free glycerol and total glycerol content in the fatty acid methyl ester (FAME or biodiesel) produced were significantly below the maximum limit of the ASTM D6751 standard. There was no trend associating changes in membrane pore size with glycerol concentration. Additionally, it was found that the water content in the FAME produced met the ASTM D6751 standard. Furthermore, the results of the soap analysis indicated that the soap dissolved in the alcohol and passed through the membrane. Thus, soap was not completely retained in the reactor. Therefore, the soap produced as a result of using high FFA feedstock in a base-catalyzed transesterification did not affect the FAME production process and the passage of mono-, di-, and triglycerides through the membrane. The quality of the biodiesel produced in this project met the requirements for the ASTM D6751 standard.
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy
Creators: name: Marenholz, Ingo
name: Grosche, Sarah
name: Kalb, Birgit
name: Rueschendorf, Franz
name: Bluemchen, Katharina
name: Schlags, Rupert
name: Harandi, Neda
name: Price, Mareike
name: Hansen, Gesine
name: Seidenberg, Juergen
name: Roeblitz, Holger
name: Yuerek, Songul
name: Tschirner, Sebastian
name: Niggemann, Bodo
name: Beyer, Kirsten
name: Lee, Young-Ae
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Allergy
subject: FOS: Clinical medicine
subject: Genome-wide association studies
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Genetic factors and mechanisms underlying food allergy are largely unknown. Due to heterogeneity of symptoms a reliable diagnosis is often difficult to make. Here, we report a genome-wide association study on food allergy diagnosed by oral food challenge in 497 cases and 2387 controls. We identify five loci at genome-wide significance, the clade B serpin (SERPINB) gene cluster at 18q21.3, the cytokine gene cluster at 5q31.1, the filaggrin gene, the C11orf30/LRRC32 locus, and the human leukocyte antigen (HLA) region. Stratifying the results for the causative food demonstrates that association of the HLA locus is peanut allergy-specific whereas the other four loci increase the risk for any food allergy. Variants in the SERPINB gene cluster are associated with SERPINB10 expression in leukocytes. Moreover, SERPINB genes are highly expressed in the esophagus. All identified loci are involved in immunological regulation or epithelial barrier function, emphasizing the role of both mechanisms in food allergy.
title: Estadificación axilar en el cáncer de mama. Anatomía y hallazgos semiológicos. Análisis de los falsos negativos de la combinación ecografía axilar-PAAF ganglionar, nuestra experiencia (2007-2011).
Creators: name: Martínez González, Judith
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Metastases
subject: Technical aspects
subject: Puncture
subject: Ultrasound
subject: Percutaneous
subject: Interventional non-vascular
subject: Anatomy
subject: Breast

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
- Descripción de las claves anatómicas de la ecografía axilar. - Presentación de los hallazgos semiológicos de sospecha.
Criterios elegidos. - Análisis de falsos negativos de la combinación ecografía axilar-PAAF ganglionar axilar en nuestra...
Object recognition in an industrial environment
Creators: name: Dunn, Jane Michelle
Publisher: name: Swinburne
Year: 2024

description: The use of automated visual inspection in industrial applications has to date been restricted to highly controlled environments. This places a limitation on the types of applications to which such systems can be applied. Increasing pressures upon manufacturing facilities in terms of cost and quality have led to an increasing demand for automated visual inspection systems. The objective of the research described in this thesis is to develop object recognition systems that are sufficiently robust to environmental variations to operate in poorly controlled industrial environments. Local feature recognition has been identified in this research as a particularly suitable object recognition method for industrial applications due to its ability to handle occlusion, clutter and noise. However this research has identified two significant sources of variation that are common to industrial environments, namely complex illumination variation and viewpoint variation that have not been effectively addressed by the local feature recognition approach. Two stages of the local feature recognition process were identified in this research as potential areas for improving the robustness to such variations: the descriptor stage and the putative interest point matching stage. Central to the improvement of the descriptor stage was the development of the Stepped Local Intensity Rank (SLIR) transform, which was designed as a potential means of providing invariance to complex illumination variation. Complex illumination invariant transforms were applied both in the forms of novel descriptors and of novel pre-processing operations to improve the system’s robustness. The second area targeted for improvement was the putative interest point matching stage, an essential element of which is the distance metric. Distance metrics used in biological applications were identified as potential sources of improvement over the standard distance metrics conventionally used in computer vision and engineering applications. Analysis of these distance metrics led to the development in this research of several novel distance metrics that outperformed the existing distance metrics in relation to illumination and viewpoint variations. The contributions of this research were evaluated against recognised benchmark descriptors and distance metrics using comparative feature recognition techniques that are commonly used throughout the literature. The novel feature recognition techniques developed in this research were found to provide significant performance improvements over the benchmarks in applications featuring complex illumination variation and viewpoint variation. Most importantly, the developed descriptors, pre-processors and distance metrics are not dependant upon characteristics that are particular to the industrial environment, and hence can be used in machine and computer vision fields in general.
title: Papel de la RM  en la predicción de la respuesta tumoral en cáncer de recto tras neoadyuvancia.
Creators: name: jiménez Veintemilla, cristina
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: Colon
subject: MR

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Evaluación de la precisión diagnóstica de la RM para la valoración del margen de resección circunferencial (MRC)y en la valoración del grado de regresión tumoral (GRT) en tumores rectales avanzados sometidos a tratamiento neoadyuvante...
title: Procesamiento de imágenes de RM para la determinación del estado y distribución de fibrosis, estatosis e inflamación hepática en pacientes con hígado graso no asociado al consumo del alcohol (NAFLD).
Creators: name: Fernandez-Arguelles, Amaya
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: MR
subject: Image manipulation / Reconstruction
subject: Outcomes analysis
subject: Liver

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Estudiar el potencial del procesamiento de imágenes de Resonancia Magnética (RM) del hígado (Figura 1),
como un método no invasivo para evaluar el estado y distribución de la fibrosis,
la esteatosis y la inflamación del hígado en pacientes...
Mechanisms and modifiers of energy metabolism in ALS and Huntington disease
Creators: name: Weydt, Patrick
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Amyotrophe Lateralsklerose
subject: Mitochondrien
subject: Morbus Huntington
subject: Neurodegeneration
subject: PGC-1alpha
subject: DDC 610 / Medicine & health
subject: Huntington disease
subject: Mitochondria
subject: Huntington-Chorea
subject: Mitochondrium
subject: Myatrophische Lateralsklerose
subject: Nervendegeneration

description: The present cumulative habilitation treatise summarizes my work on the metabolic underpinnings of neurodegenerative diseases. The work focuses on two paradigmatic neurodegenerative conditions, amyotrophic lateral sclerosis (ALS) and Huntington disease (HD). My overall goal was to exploit similarities and differences between HD and ALS to advance the understanding of neurodegeneration in general. The in vitro experiments, transgenic animal studies and human clinico-genetic studies described below led me to focus on dysregulation of the energy metabolism as a shared disease mechanism. A central finding of my thesis work is that in both conditions, HD and ALS the metabolic master switch PGC-1 alpha plays a pivotal role modifying disease progression and survival. This discovery directly and somewhat unexpectedly links transcriptional dysregulation and mitochondrial dysfunction, two aspects of neurodegeneration that were previously thought to be unrelated. As the disruption of the PGC-1 alpha pathway is recapitulated in transgenic model systems of both diseases, further research is possible (and necessary). This will help clarify the exact molecular mechanisms of metabolic dysregulation in neurodegeneration and thus contribute to defining new druggable therapeutic targets.
Supplementary document for Bidirectional mode-locked all-normal dispersion fiber laser - 4711586.pdf
Creators: name: Huang, Shu-Wei
name: li, bowen
name: Xing, Jian
name: Xie, Yijun
name: Prakash, Neeraj
name: Kwon, Dohyeon
name: Kim, Jungwon
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary Information
title: Patología mesentérica y peritoneal: desde la inflamación hasta la neo formación.
Creators: name: BALLESTEROS, ESTHER
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Abdomen
subject: CT

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Recordatorioanatómico del peritoneo y sus cavidades,
y revisión delas diferentes patologías primarias y secundarias que afectan al mesenterio y membrana peritoneal,
mostrando suaspecto ycaracterísticas distintivas en la Tomografía...
Influence of low inlet pressure and temperature on the compressor map limits of electrical turbo chargers for airborne fuel cell applications
Creators: name: Schröter, Jonas
name: Frank, Daniel
name: Radke, Valentin
name: Bauer, Christiane
name: Kallo, Josef
name: Willich, Caroline
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: compressor map
subject: pressurized fuel cell
subject: DDC 620 / Engineering & allied operations
subject: Low pressure (Science)
subject: Niederdruck

description: For the optimal high-efficiency operation of a PEM fuel cell system, the temperature, pressure, humidity and mass flow of the supplied air must be tuned to the fuel cell stack requirements. Especially for aircraft applications, this requires a thorough understanding of the fuel cell air supply system behavior and how it changes when the ambient pressure is below 1 bar(a) during flight. This work investigates the influence of low inlet pressures and varying inlet temperatures on the compression map of an electrical turbo charger. This is especially relevant in airborne fuel cell application and not much literature can be found on that topic. Compressor limits are evaluated experimentally and theoretically. The theory of mass flow and speed correction is compared to experimental findings and found to be applicable for the surge and speed limit of the investigated turbo chargers as long as the compressor map is not limited by the power of the electric motor and inverter. Based on this, a prediction of the compressor map for altitudes up to 10,000 m is made with the help of a developed software tool.
Point of care ultrasound training for internal medicine: a Canadian multi-centre learner needs assessment study
Creators: name: Watson, Kathryn
name: Lam, Ada
name: Arishenkoff, Shane
name: Halman, Samantha
name: Gibson, Neil E.
name: Yu, Jeffrey
name: Myers, Kathryn
name: Mintz, Marcy
name: Ma, Irene W. Y.
Publisher: name: BioMed Central
Year: 2018

description: Background: Significant gaps currently exist in the Canadian internal medicine point-of-care ultrasound (POCUS) curriculum. From a learner’s perspective, it remains unknown what key POCUS skills should be prioritized. This needs assessment study seeks to establish educational priorities for POCUS for internal medicine residents at five Canadian residency training programs. Methods: All internal medicine trainees [postgraduate year (PGY) 1–5] from five internal medicine residency training programs in Canada (n = 598) were invited to complete an online survey on 15 diagnostic POCUS applications, 9 bedside procedures, and 18 POCUS knowledge items. For POCUS applications and procedures, participants were asked how applicable they are to patient care in internal medicine and the participants’ reported skills in those domains. Self-reported knowledge and skills were rated on a 5-point Likert scale, where 1 = very poor and 5 = very good. Applicability was rated, where 1 = not at all applicable and 5 = very applicable. Results: A total of 253 of 598 residents (42%) participated in our study. Data from one centre (n = 15) was removed because of low response rate (15%) and significant baseline differences between those trainees and the remaining participants. Of the remaining analyzable data from four training programs (n = 238), participants reported highest applicability to internal medicine for the following applications and procedures: identifying ascites/free fluid [mean applicability score of 4.9 ± standard deviation (SD) 0.4]; gross left ventricular function (mean 4.8 ± SD 0.5) and pericardial effusion (mean 4.7 ± SD 0.5); thoracentesis (mean score 4.9 ± SD 0.3), central line insertion (mean 4.9 ± SD 0.3), and paracentesis (mean 4.9 ± SD 0.3), respectively. Overall reported knowledge/skills was low, with skill gaps being the highest for identifying deep vein thrombosis (mean gap 2.7 ± SD 1.1), right ventricular strain (mean 2.7 ± SD 1.1), and gross left ventricular function (mean 2.7 ± SD 1.0). Conclusions: Many POCUS applications and procedures were felt to be applicable to the practice of internal medicine. Significant skill gaps exist in the four Canadian training programs included in the study. POCUS curriculum development efforts should target training based on these perceived skill gaps.