cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Laparoscopic Adrenalectomy; A Short Summary with Review of Literature
Creators: name: Chalkoo, Mushtaq
name: Awan, Naseer
name: Makhdoomi, Hilal
name: Arsalan, Syed Shakeeb
name: Raja, Waseem
Publisher: name: figshare
Year: 2017
Subjects: subject: 119999 Medical and Health Sciences not elsewhere classified
subject: FOS: Other medical sciences
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: The adrenal glands were first described by the Italian anatomist Bartolommeo Eustachi in 1563. The adrenal glands are mustard coloured structures positioned superior and slightly medial to the kidneys in the retroperitoneal space, flattened and roughly pyramidal or crescent shaped weighing 4 Gms each. They are among the highly perfused organs of the body. The right adrenal gland abuts the postero- lateral surface of the hepatic vene cava bounded by the right kidney infero-laterally, diaphragm posteriorly and bare area of the liver anterosuperiorly. The left adrenal lies between left kidney and aorta with inferior limb extending farther caudad towards renal hilum [1]. The German comparative anatomist Albert Von Kolliker is credited with first identifying two distinct portions of the adrenal gland, the cortex and the medulla. Each adrenal gland is composed of 2 distinct parts: the adrenal cortex and the adrenal medulla. The cortex is divided into 3 zones. From exterior to interior, these are the zona glomerulosa, the zona fasciculata, and the zona reticularis. Edward Kendall, Tadeus Reichitein and Philpi Hench jointly received the 1950 Nobel Prize in Physiology and Medicine for their groundbreaking work on adrenocortical hormones. The adrenal cortex secretes 3 types of hormones: (1) mineralocorticoids (the most important of which is aldosterone), which are secreted by the zona glomerulosa; (2) glucocorticoids (predominantly cortisol), which are secreted by the zona fasciculata and, to a lesser extent, the zona reticularis; and (3) adrenal androgen (mainly dehydroepiandrosterone [DHEA]), which is predominantly secreted by the zona reticularis, with small quantities released from the zona fasciculate. The adrenal medulla is a completely different entity secreting epinephrine (80%) and norepinephrine (20%), with minimal amounts of dopamine. These hormones are responsible for an increase in cardiac output and vascular resistance and for all the physiologic characteristics of the stress response.
Natural and effective ways of purifying lake water
Creators: name: Swapnil Lokhande
name: Dixit, Savita
Publisher: name: figshare
Year: 2017
Subjects: subject: 120402 Engineering Design Knowledge
subject: FOS: Other engineering and technologies
subject: 120404 Engineering Systems Design

description: Water resources play an integral part in the life of a living being. The various water resources that are present on the earth’s surface are in the form of oceans, seas, lakes, rivers, ponds, waterfalls etc. Among these water resources Lakes and reservoirs are vital for people’s life, industrial activities and many other day to day activities. These water resources help in obtaining water for drinking after being treated. They also provide water for agriculture and industrial usage, fishery resource, flood control functions and many other activities. Due to the closed nature of lakes’, the waste material from sewage, agricultural effluents, domestic and industrial fields, gets accumulated around the surface of these water resources and once the water gets polluted, it gets strenuous to improve the quality of the water. In the study, the authors have examined different effective ways by which the quality of lake water can be improved.
Membership Inference Attacks Against Recommender Systems
Creators: name: Zhang, Minxing
name: Ren, Zhaochun
name: Wang, Zihan
name: Ren, Pengjie
name: Chen, Zhumin
name: Hu, Pengfei
name: Zhang, Yang
Publisher: name: CISPA
Year: 2023

description: Recently, recommender systems have achieved promising performances and become one of the most widely used web applications. However, recommender systems are often trained on highly sensitive user data, thus potential data leakage from recommender systems may lead to severe privacy problems.
In this paper, we make the first attempt on quantifying the privacy leakage of recommender systems through the lens of membership inference. In contrast with traditional membership inference against machine learning classifiers, our attack faces two main differences. First, our attack is on the user-level but not on the data sample-level. Second, the adversary can only observe the ordered recommended items from a recommender system instead of prediction results in the form of posterior probabilities. To address the above challenges, we propose a novel method by representing users from relevant items. Moreover, a shadow recommender is established to derive the labeled training data for training the attack model. Extensive experimental results show that our attack framework achieves a strong performance. In addition, we design a defense mechanism to effectively mitigate the membership inference threat of recommender systems.
Successful Therapy with intravenous gamma globulin in two children with postinfectious bronchiolitis obliterans
Creators: name: Pekcan, Sevgi
name: Gökturk, Bahar
name: Reisli, Ismail
Publisher: name: figshare
Year: 2017
Subjects: subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: A 21 month-old boy was admitted with the complaints of hacking cough, wheezing, difficulty in breathing for 4 months. From the history; he needed mechanical ventilation due to a severe adenoviral pneumonia (adenovirus PCR was positive on nasal swab), was diagnosed as bronchiolitis obliterans (BO), 1mg/kg methylprednisolone was continued for 4 weeks, was discharged to home with oxygen replacement, and hospitalized 5 more times in a 4 month period. His weight was 10600gr (10-25p), height was 83.5cm (25p). On physical examination, there were tachpnea, central cyanosis, bilateral rales and rhonchi. Chest computerized tomography demonstrated mosaic pattern and ground glass opacities. Immunodeficiency, cystic fibrosis, allergic hypersensitivity and tuberculosis were excluded (Data not shown). Methylprednisolon treatment (1mg/kg/day) was restarted, but he had to be hospitalizated for three times during reduction period of steroid. Steroid dosage had to be increased during hospitalizations. Azithromycin prophylaxis was started 3 times a week during reduction period of steroid, and continued for 5 months, but clinical improvement could not be achieved. Angiotensin converting enzyme inhibitor was started while his pulmonary artery pressure was 29 mmHg. The family was convinced to move to another house due to intense moisture and mould. While clinical improvement couldn’t be achieved, intravenous immunoglobulin G (IVIG) replacement every 3 weeks for a dose of 400 mg/kg was started when he was 30 month-old. During 6 doses IVIG replacement, only one hospitalization was needed at winter time, and his need for oxygen was disappeared. The replacement of IVIG was stopped when he was 35 month-old. After termination of IVIG replacement, he was hospitalized for 2 times when he was 38 and 40 month old, so IVIG replacement was given for 3 times more. He is now 72-month old, takes inhaled corticosteroids, azithromycine propylaxis for 6 months in a year. He has no cough, tachypnea, exercise intolerance, rales, and need for oxygen anymore. The last pulmonary artery pressure was detected as 20mmHg. His body weight: 16.5 kg (50-75p), height: 104 cm (75p). Radiological imagings were shown in figure 1.
Theory and Experiments. (+) Add Reading Glasses to Prevent Myopia
Creators: name: Greene, Peter R
name: Brown OS
Publisher: name: figshare
Year: 2017
Subjects: subject: 111301 Ophthalmology
subject: FOS: Clinical medicine
subject: 111399 Ophthalmology and Optometry not elsewhere classified

description: Basic control theory equations are developed showing conventional exponential system response of refraction vs. time R (t) with a characteristic system time constant, in response to a step change of near work environmental conditions. Details from preliminary experimental design using reading glasses at the U.S. Naval Academy at Annapolis are discussed. The conclusion is that (+) add lenses, used as reading glasses during study, can prevent the development of myopia for college students in pilot training.
Phenibut Overdose in Combination with Fasoracetam: Emerging Drugs of Abuse
Creators: name: Merchan, Cristian
name: Morgan, Ryan
name: Papadopoulos, John
name: Fridman, David
Publisher: name: figshare
Year: 2017
Subjects: subject: 110310 Intensive Care
subject: FOS: Clinical medicine

description: The widespread availability of non-traditional dietary supplements and pharmacologically active substances via the Internet continues to introduce mechanisms for inadvertent toxidromes not commonly seen. Consumers are virtually unrestricted in their ability to acquire products purporting augmentation of normal physiology for the purposes of enhancement, recreation, and/or potential abuse. The safety profiles at standard or toxic doses remain largely unknown for many agents that can be purchased electronically. We report a case of mixed toxicity related to phenibut and fosaracetam, both of which are readily available for consumer purchase from online retailers. Written and verbal consent was obtained for this case presentation.
title: Vorwort
title: in: Christliche Sozialethik
titleType: Subtitle
Creators: name: Heimbach-Steins, Marianne
name: Becka, Michelle
name: Frühbauer, Johannes J.
name: Kruip, Gerhard
Publisher: name: University of Muenster, Institutional Repository MIAMI
Year: 2022
Subjects: subject: 241 Christian ethics
subject: 230 Christianity
subject: 300 Social sciences, Anthropology

description: Die Publikation des Lehrbuchs wird gefördert durch: die Ketteler-Studienstiftung im Bistum Mainz und den Verein der Freunde des Instituts für christliche Sozialwissenschaften der WWU.
A Preliminary Laboratory Investigation of Methane Generation Potential from Brewery Wastewater using UASB Reactor
Creators: name: MA Karim
name: Moss, Benjamin L
Publisher: name: figshare
Year: 2017
Subjects: subject: 120402 Engineering Design Knowledge
subject: FOS: Other engineering and technologies
subject: 120404 Engineering Systems Design

description: A preliminary laboratory study was conducted using upflow anaerobic sludge blanket (UASB) reactor to investigate the potential of methane generation from brewery wastewater. Brewery wastewater from a local brewery company was collected and used in the experiments. The experiments were run for 15 days. The rate of methane production was about 5.32 L per kg of chemical oxygen demand (COD) removed per day. The pH reduction in the experimental reactor limited the ability of gas production and is likely the result of the temperature at which the experiments were conducted.
A Comparative Study of Anatomic and Functional Outcomes of Two Surgical Techniques of Cataract at Lome
Creators: name: Ayena KD
name: KAM, Santos
name: Vonor K
name: Amedome KM
name: Wodome A
name: Strauss G
name: Nagbe YE
name: Koffi-Ametooyona A
name: Balo K
Publisher: name: figshare
Year: 2017
Subjects: subject: 111301 Ophthalmology
subject: FOS: Clinical medicine
subject: 111399 Ophthalmology and Optometry not elsewhere classified

description: Aim: To compare the anatomical and functional outcomes of cataract surgery with manual small incision cataract surgery (MSICS) to those of extracapsular cataract extraction (ECCE) in Lome. Patients and Methods: A prospective study involved two groups of patients who underwent ECCE (group 1) and MSICS (group 2) by the same surgeon in the same conditions in different periods. Complications and visual results to the 45th postoperative day were compared. Results: At the 45th postoperative day, 60% of operated eyes of the ECCE group (G1) and 83.9% in the group of MSICS (G2) had uncorrected visual acuity greater than or equal to 3/10. Through the pinhole, these proportions increased to 73.3% for G1 and 92.2% for G2. Visual acuity was less than 1/10 in 4.4% for G1 and 1.1% for G2. The vitreous loss was observed in proportions of 3.8% for G1 and 3.3% for G2. During follow-up, the three main early postoperative complications were inflammation (13.9%), corneal edema (13.3%), and the pigment dispersion (7.2%) in G1 and corneal edema (9.4%), pigment dispersion (8.3%) and hypertonia (6.6%) in G 2. Conclusion: Two cataract extraction techniques offer the same level of safety in intraoperative period. However, MSICS has certain advantages over the ECCE and would be an alternative technique in developing countries.
Hydraulic jump experiment in a rectangular open channel flume
Creators: name: El-Seddik, Mostafa M
Publisher: name: figshare
Year: 2017
Subjects: subject: 120402 Engineering Design Knowledge
subject: FOS: Other engineering and technologies
subject: 120404 Engineering Systems Design

description: This paper presents a laboratory experiment for the formation of hydraulic jump in a rectangular open channel flume to accurately explore the effect of flow structures on water resources. This experiment illustrates the behavior of super-critical flow under sluice gate for various flow rates and downstream depths. Several runs are carried out using Armfield Model No. C4-MKII-5.0-11 to investigate the former computations concerning both the downstream conjugate depth and the critical depth resulting within the jump. Moreover, the model is examined to explore the sensitivity of Froude number by adjusting the flow-meter and over-shot weir in the flume. Also, the type of jump attributed to flow velocity can thus be obtained. Furthermore, both location of hydraulic jump and energy dissipated are discussed under the influence of different gate openings.
Acute and chronic changes in massive Barium Sulfate aspiration in an infant who subsequently was diagnosed with severe Gastro-esophageal Reflux
Creators: name: Pekcan, Sevgi
Publisher: name: figshare
Year: 2017
Subjects: subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: The barium is often used in radiocontrast examinations of the digestive system because of mucosal absorption is limited. Massive barium aspiration is a rare complication, especially when there is no anatomic or neurological deficit. The depending on barium concentration can cause various lung effects. When the literature is reviewed, barium aspiration may be asymptomatic or lethal in massive amounts. Rarely, large amounts of barium sulphate are aspirated into the lung, there is no literature study how often this is happening.
We present a case of massive barium aspiration in this subject. The case is related to a patient’s diagnostic esophagography who complaints swallowing problems. The massive barium aspiration couldn’t notice because of the absence of acute symptoms and surgical operation of gastrointestinal tract which the patient had undergone previously. When the patient applied our Pediatric Chest Diseases Polyclinic after three months, as a result of the examinations and deep research it was understood that the case was about massive barium aspiration. The patient was directed to our center because there was a radiological appearance of bone density signs on chest X-ray. Such a complaint was not reported by the family neighter in his biography, nor was written in the epicrisis. We will share acute and chronic changes in the lungs, diagnosis and treatment approaches of this case. The infant who has ileostomy was previously operated because of necrotizing enterocolitis. And also still has severe gastro-esophageal reflux and under conservative and medical treatment, a possible fundoplication surgery is planning.
Continuous Release of Data Streams under both Centralized and Local Differential Privacy
Creators: name: Wang, Tianhao
name: Chen, Joann Qiongna
name: Zhang, Zhikun
name: Su, Dong
name: Cheng, Yueqiang
name: Li, Zhou
name: Li, Ninghui
name: Jha, Somesh
Publisher: name: CISPA
Year: 2023

description: We study the problem of publishing a stream of real-valued data satisfying differential privacy (DP). One major challenge is that the maximal possible value in the stream can be quite large, leading to enormous DP noise and bad utility. To reduce the maximal value and noise, one way is to estimate a threshold so that values above it can be truncated. The intuition is that, in many scenarios, only a few values are large; thus truncation does not change the original data much. We develop such a method that finds a suitable threshold with DP. Given the threshold, we then propose an online hierarchical method and several post-processing techniques.

Building on these ideas, we formalize the steps in a framework for the private publishing of streaming data. Our framework consists of three components: a threshold optimizer that privately estimates the threshold, a perturber that adds calibrated noise to the stream, and a smoother that improves the result using post-processing. Within our framework, we also design an algorithm satisfying the more stringent DP setting called local DP. Using four real-world datasets, we demonstrate that our mechanism outperforms the state-of-the-art by a factor of $6-10$ orders of magnitude in terms of utility (measured by the mean squared error of the typical scenario of answering a random range query).
Fighting Today for a Better Tomorrow
Creators: Martin, Jesse T.
Publisher: name: Columbia University
Year: 2019
Subjects: Human rights
Indigenous peoples
Indigenous youth
Indigenous peoples--Politics and government
Indigenous peoples--Economic conditions
Indigenous peoples--Social conditions

description: For millennia, my people have been the stewards of this land. Coming from a place rich with everything one could want for, my ancestors lived by a strict and binding law which dictated that each individual would look out for the collective and the collective would look after each individual. A circle of balance, with this knowledge and responsibility, passed from one generation to the next. With a governing core philosophy which stressed the importance of individual responsibility for the betterment of each other, my people created a balance with themselves and the world around them. The arrival of Europeans and the Western identity changed this world forever, and now the modern age has heralded changes for us which we must look to overcome, to adapt to, to survive and to thrive alongside in this new world. Although split into many tribes and clans across the country, Aboriginal and Torres Strait Islander people as a whole constitute the longest continuing culture on the planet, with my people being here over 50,000 years. However, it is important to stress that for this time, we have not remained fixed in time as some of the Western stereotypes may depict the image of the unchanged “noble savage.” No, we have been able to survive and thrive as long as we have due to the fact that we are the most adaptive people on this earth. As circumstance and necessity dictate, so we adapt, and so we overcome. Today this same principle applies, and although we have a drastically altered and different experience ahead of us, drawing upon the same core philosophy of our past we indeed shall not only survive but thrive, adapting to a new world and once again showing why we indeed are the longest continuing culture in the world to date.
Plume Analysis from Field Evaluations of a Portable Air Quality Monitoring System
Creators: name: Marto, Joseph P
name: Zhang, Jie
name: Schwab, James J.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Near road measurements in Rochester, NY with a Portable Air Quality Monitoring System indicate a significant plume control of PM2.5 black carbon (BC) concentrations. This study evaluates the performance of two portable air quality enclosures deployed at collocated research sites to determine their accuracy and usefulness in field deployments, and specifically in pollution plume analysis. One system deployed collocated sensors for measurement of particulate matter mass concentration (Thermo pDR 1500 against Tapered Element Oscillating Microbalance (TEOM) measurement) and the second system deployed sensors for measurement of black carbon (Magee AE33 aethalometer and Brechtel Tricolor Absorption Photometer) in ambient and near road locations in Rochester, New York, respectively. While the optical PM2.5 sensors tended to be biased in their determination of concentration by ~15%, they followed changes and trends in concentration very well. The black carbon sensors in the portable systems agreed very well with each other and with the collocated sensor. As a case study to determine the contribution from statistically significant short-lived excursions of pollutant concentration, Morlet wavelet analysis was performed on data from the portable system sensors. Black carbon was found to be strongly influenced by plume behavior with significant plume excursions representing just over 12% of all data points and contributing on average 1 µg/m3 of black carbon above ambient concentrations.
Implications Statement This paper first evaluates two air pollutant monitoring enclosures with wide applicability including near road detection of pollutants. Then, we present a novel method to designate isolate statistically significant excursions in air pollution concentration which can be used to determine the impact of pollutant plumes as observed in PM and black carbon behavior near road.
 Implications Statement This paper first evaluates two air pollutant monitoring enclosures with wide applicability including near road detection of pollutants. Then, we present a novel method to designate isolate statistically significant excursions in air pollution concentration which can be used to determine the impact of pollutant plumes as observed in PM and black carbon behavior near road.
Avoiding confusion in high flow oxygen therapy concepts
Creators: name: García G
name: Agosta M
name: P, Valencia
name: E, Mercedes
name: Sarhane Y
name: Díaz-Lobato S
Publisher: name: figshare
Year: 2017
Subjects: subject: 110203 Respiratory Diseases
subject: FOS: Clinical medicine

description: Oxygen therapy is the main supportive treatment in hypoxemic respiratory failure and has traditionally been delivered using low and high flow devices. However, the maximal flow rates that these devices can deliver are limited because of the insufficient heat and humidity provided to the gas administered. Low flow devices such as the nasal cannula, conventional face mask and reservoir bag deliver a flow rate of up to 15 L/min by administering more variable oxygen fractions (FiO2), depending on the patient’s respiratory pattern, peak inspiratory flow and characteristics of the devices. Conventional high flow devices, such as venturi type masks, utilize a constant flow of oxygen through precisely sized ports, entraining the ambient air, using the Bernoulli principle, providing a more constant inspired oxygen fraction. However, they are less tolerated than nasal cannulas because they are less comfortable and the insufficient humidification and heating of the gas delivered [1].
Wave Forces on Vertical Structures in Shallow Water: Numerical Evaluation
Creators: name: Dentale, Fabio
name: Reale, Ferdinando
name: Leo, Angela Di
name: Carratelli, Eugenio Pugliese
name: Monaco, Marina
Publisher: name: figshare
Year: 2017
Subjects: subject: 120402 Engineering Design Knowledge
subject: FOS: Other engineering and technologies
subject: 120404 Engineering Systems Design

description: The actions exerted by waves on a coastal structure very much depend upon hydrodynamic processes that originate on shallow waters; even though significant progresses have been made in the last few years towards a full understanding of wave breaking, design work is still largely based on classical stability formulas. The recent availability of reliable models based on the numerical integration of full Navier-Stokes equations provides an important tool, but the evaluation of forces on vertical structures in shallow waters is still a particularly delicate application because of the complex hydrodynamic issues involved. The paper presents deals with the numerical simulation of wave effects on front of a vertical obstacle on a sloping bottom, with the objective of clarifying some physical issues which are relevant towards the applicability of numerical Navier-Stokes simulation as a design tool.
French Film Colorists
Creators: Yumibe, Joshua
Publisher: name: Columbia University
Year: 2020
Subjects: Women in the motion picture industry
Motion pictures
Silent films

description: Perhaps the earliest production work available to women in the film industry was coloring work—hand-coloring dyes onto film prints frame by frame. Female colorists were also common in the nineteenth century in the lantern-slide and postcard industries, for at least initially, they could be exploited at a lower wage than men to perform the repetitive and detailed tasks. By the mid-1890s, the film industry had adopted similar labor strategies for coloring prints. Aesthetic assumptions also grounded this practice: an enduring trope of western color theory pertains to the gendering of color—females have long been assumed to be more attuned to color. Women were not only cheaper in general to employ but also were thought to be, with their supposed sensitivity and nimble fingers, innately suited to the detailed work of coloring films.
French Film Colorists
Creators: Yumibe, Joshua
Publisher: name: Columbia University
Year: 2013
Subjects: Women in the motion picture industry
Motion pictures
Silent films

description: Perhaps the earliest production work available to women in the film industry was coloring work—hand-coloring dyes onto film prints frame by frame. Female colorists were also common in the nineteenth century in the lantern-slide and postcard industries, for at least initially, they could be exploited at a lower wage than men to perform the repetitive and detailed tasks. By the mid-1890s, the film industry had adopted similar labor strategies for coloring prints. Aesthetic assumptions also grounded this practice: an enduring trope of western color theory pertains to the gendering of color—females have long been assumed to be more attuned to color. Women were not only cheaper in general to employ but also were thought to be, with their supposed sensitivity and nimble fingers, innately suited to the detailed work of coloring films.
Further Assimilation
Creators: Lifjell, Ole-Henrik
Publisher: name: Columbia University
Year: 2019
Subjects: Human rights
Indigenous peoples
Indigenous youth
Sami (European people)
Assimilation (Sociology)

description: My name is Ole-Henrik Lifjell. I am a 24-year-old Sámi on the Norwegian side of Sápmi. I am what you call an Åarjel-saemie, a southern Sámi. Sápmi is the term we Sámi use to refer to the geographical area in which we reside. This includes the countries of Norway, Sweden, Finland and Russia. The Sámi are widely spread out and there are cultural differences and differences in language between us, even though we are one People. We see that the way the Sámi are treated by governments also differs among the four countries in which we live. This has historically made—and still makes—it difficult for us Sámi to stand united as one People. We do not face the same challenges in our respective countries, and the governments in each country have different histories in the way they treated our ancestors (and how that has led to the way we are treated today). This is something that, in my experience, is dividing us Sámi.
Generation of pralatrexate resistant T-cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers
Creators: Scotto, Luigi
Kinahan, Cristina
Casadei, Beatrice
Mangone, Michael
Douglass Jr, Eugene F.
Vundavalli, Murty V.
Marchi, Enrica
Ma, Helen
Chauncey, George
Montanari, Francesca
Califano, Andrea
O’Connor, Owen Anthony
Publisher: name: Columbia University
Year: 2020
Subjects: Lymphomas
Drug resistance

description: While pralatrexate (PDX) has been successfully developed for the treatment of T-cell lymphoma, the mechanistic basis for its T-cell selectivity and acquired resistance remains elusive. In an effort to potentially identify synergistic combinations that might circumnavigate or delay acquired PDX resistance, we generated resistant cells lines over a broad concentration range. PDX-resistant cell lines H9-12 and H9-200 were developed, each exhibiting an IC50 of 35 and over 1000 nM, respectively. These lines were established in vitro from parental H9 cells. Expression analysis of the proteins known to be important determinants of antifolate pharmacology revealed increase expression of dihydrofolate reductase (DHFR) due to gene amplification, and reduced folate carrier1 downregulation, as the putative mechanisms of resistance in H9-12 and H9-200 cells. Cross resistance was only seen with methotrexate but not with romidepsin, azacitidine (AZA), decitabine, gemcitabine, doxorubicin, or bortezomib. Resistance to PDX was reversed by pretreatment with hypomethylating agents in a concentration-dependent fashion. Comparison of gene expression profiles of parental and resistant cell lines confirmed markedly different patterns of gene expression, and identified the dual specificity phosphatase four (DUSP4) as one of the molecular target of PDX activity. Reduced STAT5 phosphorylation following exposure to PDX was observed in the H9 but not in the H9-12 and H9-200 cells. These data suggest that combination with hypomethylating agents could be potent, and that DUSP4 and STAT5 could represent putative biomarkers of PDX activity.
THR and TKR procedures performed between 1989 and 2013 at the Royal Adelaide Hospital
Creators: name: Phipps, Bethany
name: Solomon, Patricia
name: Tuke, Simon
name: Solomon, Bogdan
name: Costi, Kerry
Publisher: name: The University of Adelaide
Year: 2017
Subjects: subject: 10301 Numerical Analysis
subject: FOS: Mathematics
subject: 10402 Biostatistics

description: Mathematical modelling of data related to THR (total hip replacement) and TKR (total knee replacement) procedures.
AHEAD: Adaptive Hierarchical Decomposition for Range Query under Local Differential Privacy
Creators: name: Du, Linkang
name: Zhang, Zhikun
name: Bai, Shaojie
name: Liu, Changchang
name: Ji, Shouling
name: Cheng, Peng
name: Chen, Jiming
Publisher: name: CISPA
Year: 2023

description: For protecting users' private data, local differential privacy (LDP) has been leveraged to provide the privacy-preserving range query, thus supporting further statistical analysis. However, existing LDP-based range query approaches are limited by their properties, i.e., collecting user data according to a pre-defined structure. These static frameworks would incur excessive noise added to the aggregated data especially in the low privacy budget setting. In this work, we propose an Adaptive Hierarchical Decomposition (AHEAD) protocol, which adaptively and dynamically controls the built tree structure, so that the injected noise is well controlled for maintaining high utility. Furthermore, we derive a guideline for properly choosing parameters for AHEAD so that the overall utility can be consistently competitive while rigorously satisfying LDP. Leveraging multiple real and synthetic datasets, we extensively show the effectiveness of AHEAD in both low and high dimensional range query scenarios, as well as its advantages over the state-of-the-art methods. In addition, we provide a series of useful observations for deploying AHEAD in practice.
Plant cell wall focused transcriptome and genomic sequence datasets
Creators: name: Schwerdt, Julian
name: Fincher, Geoffrey
name: Burton, Rachel
name: Shirley, Neil
Publisher: name: The University of Adelaide
Year: 2017
Subjects: subject: 60702 Plant Cell and Molecular Biology
subject: FOS: Biological sciences

description: This collection includes sequencing reads of plant and algal species generated by Illumina HiSeq and Ion Torrent PGM platforms. Transcriptomes include a wide sampling across tissues and plant varieties for comparative expression analysis. Genomes are of plants and algae significant to our research into the synthesis and organisation of plant cell wall, and its polysaccharides. The collection also includes associated phylogenetic and mapping analyses. Additional data will be added over the period of the operation of the Centre of Excellence (2011 - 2017).
13 pieśni na pochwałę wina.pdf
Creators: name: Olszewski, Krzysztof
Publisher: name: figshare
Year: 2017
Subjects: subject: 200312 Japanese Language
subject: FOS: Languages and literature

description: Polskie tłumaczenie arcydzieła japońskiej pieśni biesiadnej z VIII w. - 13 strof na pochwałę wina, Otomo no Tabito.
MOESM1 of Transcriptome analysis reveals an important candidate gene involved in both nodal metastasis and prognosis in lung adenocarcinoma
Creators: name: Zhu, Xiao
name: Luo, Hui
name: Xu, Ying
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology

description: Additional file 1: Table S1. The top 10 significant down- and up-regulated genes associated with lung adenocarcinoma.
The Gradient Discretisation Method For Variational Inequalities
Creators: name: YAHYA AHMED M ALNASHRI
Publisher: name: Monash University
Year: 2017
Subjects: subject: 10301 Numerical Analysis
subject: FOS: Mathematics
subject: 10110 Partial Differential Equations

description: The purpose of this thesis is to develop a gradient discretisation method for elliptic and parabolic, linear and non-linear, variational inequalities. The gradient discretisation method is a framework which enables a unified convergence analysis of many different methods – such as finite elements (conforming, non-conforming and mixed) and finite volumes methods – for 2nd order diffusion equations. Using the gradient discretisation method framework, we perform the numerical analysis of variational inequalities. We first establish error estimates for numerical approximations of linear elliptic variational inequalities. Using compactness techniques, we prove the convergence of numerical schemes for non-linear elliptic variational inequalities based on Leray–Lions operators. We also show the uniform-in-time convergence for linear parabolic variational inequalities. As numerical applications of this framework, we design, analyse and test the hybrid mimetic mixed (HMM) method for variational inequalities.
Kulturelle Institutionen
Creators: name: Bednarczuk, Monika
Publisher: name: Zenodo
Year: 2014
Subjects: Poland, interwar period, cultural institutions, state support of culture

description: In: Ulrich Schmid / Isabelle Vonlanthen / Sabina Schaffner (Hg.): Schwert, Kreuz und Adler. Die Ästhetik des nationalistischen Diskurses in Polen (1926−1939). Harrassowitz: Wiesbaden 2014, 196–216.
Study 2 Video of Procedures
Creators: name: Hickey, Paige Connors
name: Urry, Heather L.
name: Garay, Maria
name: Pagan, Jeremy
name: Raea E. Rasmussen
name: Eddine, Samer Nour
Publisher: name: OSF Registries
Year: 2020

description: In this component you'll find a video of someone completing our Qualtrics survey for Study 2. The version shown involves compensation in the form of entry into a drawing. Experimenters will not be present when participants complete the study, thus none are shown in the video.
Vaḷīpaṭṭana : The Shilāhāra Capital
Creators: name: RODRIGUES, TENSING CARLOS
Publisher: name: figshare
Year: 2017
Subjects: subject: History
subject: Anthropology
subject: FOS: Sociology
subject: Geography
subject: Sociology

description: What’s more interesting is that the 1008 CE Khārepāṭaṇa plates seem to suggest that Baḷipaṭṭana was indeed in Goa. These plates record the grant of some villages by king Raṭṭarāja to the temple dedicated to Avvēśvara. “I have donated in honour of my parents and for my own spiritual welfare - on the full-moon tithi of Jyēsṭha in the years nine hundred increased by thirty which have elapsed by the era of the Saka king, the cyclic year being Kīlaka, for the worship with fivefold of offerings of the holy Avvēśvara, … (1) the village of Kuśmānḍī, the boundaries of which are on the east, the prapā of Manigrāma on the south, by the road to the village of Vāparavaṭa, on the west, by the water-course of the village Sachāndalakapittha, and on the north by a kshāra-nadī. (2) the village of Asanavīra; which has on the east Dhārāvāhala, on the south, the river of the village Kāraparṇī, on the west, the sea, and on the north, the river of the village Gāvahaṇa.” [Mirashi, 1977 : 192]
Challenging pro-criminal attitudes and behaviours of juvenile offenders
Creators: name: PHILLIPA JEAN EVANS
Publisher: name: Monash University
Year: 2017
Subjects: subject: 160701 Clinical Social Work Practice
subject: FOS: Sociology

description: Whilst research identifies pro-criminal beliefs and attitudes as strong risk factors for offending and re-offending, there is limited research informing workers about how to respond to these comments. This study explores the extent to which juvenile justice workers challenge young people about pro-criminal comments and how clients respond to the various challenging methods and skills used by workers. To understand the workers’ use of challenging, observations of supervision sessions between young people and their juvenile justice workers were undertaken. The findings reveal that young people commonly make pro-criminal and antisocial comments and workers challenge these comments in a range of ways that both engage and fail to engage young people.
Why mixed-nitrogen nutrition increases drought tolerance in rice: from plant growth, to mesophyll conductance and photochemical efficiency
Creators: name: Xiaochuang Cao
Publisher: name: figshare
Year: 2017
Subjects: subject: 60705 Plant Physiology
subject: FOS: Biological sciences

description: Fig. 1 Rice xylem sap amount (A), root secretion rate (B) and water use efficiency (WUE) (C) of rice plants subjected to different N forms and water regimens. N, NP, A, AP, NA and NAP represent the nitrate (NO3-), NO3-+PEG 6000, ammonium (NH4+), NH4++PEG 6000, mixture of NO3- and NH4+ (NO3-+NH4+) and NO3-+NH4++PEG 6000 treatments, respectively. The same occurs below. Fig. 2 Rice leaf Chl (A), total N (B) and Rubisco (C) contents of rice plants subjected to different N forms and water regimens. Fig. 3 Concentrations of soluble sugars and starch in the leaves and roots of rice seedlings subjected to different N forms and water regimens.Fig. 4 The CO2 response curves of rice plants subjected to different N forms and water regimens.Fig. 5 Leaf photosynthetic rate (Pn), stomatal CO2 diffusion conductance (gs), intercellular CO2 concentration (Ci), and transpiration rate (Tr) of rice plants subjected to different N forms and water regimens under the 400 µmol mol-1 CO2 concentration. Fig. 6 The relationships of net photosynthesis A) and water use efficiency (WUE) to the mesophyll diffusion conductance (gm), stomatal CO2 diffusion conductance (gs) and the ratio of gm to gs in rice leaves.
Poster: Visualizing metabolomics data in directed biological networks
Creators: name: Kutmon, Martina
name: Miller, Ryan
name: Slenter, Denise
name: Evelo, Chris
name: Willighagen, Egon
Publisher: name: figshare
Year: 2017
Subjects: subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Computational Biology
subject: 60114 Systems Biology
subject: FOS: Biological sciences

description: We developed a new solution to visualize the biological pathways involved in sparse metabolomics data. Using knowledge from two pathway resources and ontology-based approaches, we can show the directed networks between active metabolites from metabolomics data. The data from both resources is made interoperable by collapsing metabolites in the pathways into single nodes in the biological networks using ontological approaches. This explicit ontological linking allows for precise biological interpretation of the paths. By using Neo4j and Cytoscape, we ensure the computational calculation environment for larger networks as well as advanced visualization functionality to investigate the identified subnetworks. The generic nature of this approach opens up the option to combine with other omics data sources, such as proteomics and transcriptomics.
Constructing Contemporary Konkaṇ
Creators: name: RODRIGUES, TENSING CARLOS
Publisher: name: figshare
Year: 2017
Subjects: subject: History
subject: Anthropology
subject: FOS: Sociology
subject: Archaeology
subject: Geography

description: Is trans-Sahyadri Konkan relevant today ? At some point in history, Konkan did perhaps occupy a vast swathe of land across the ancient mountains. But contemporary Konkan – the territory where Konkani is spoken as the native language - includes much less - some districts, wholly or partly, of Maharashtra and Karnataka, besides the whole of Goa. But leaving out Goa, all other Konkani areas, Sindhudurga, Ratnagiri and Raigad districts of Maharashtra, and Uttar Kannada, Udupi, Belgaum, Dharwad, Shimoga and Dakshin Kannada districts of Karnataka include trans-Sahyadri territories. These vestiges of the trans-Sahyadri Konkan are not just of a historical significance; they make Konkan ecologically self-contained, and therefore make eminent economic and social sense. Perhaps this would have been the case of Goa too; though the Portuguese acquired Goa with a trans-Sahyadri complement, they chose to cede that away, probably for administrative reasons.
MOESM2 of Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data
Creators: name: Liu, Fenglin
name: Zhang, Yuanyuan
name: Zhang, Lei
name: Li, Ziyi
name: Fang, Qiao
name: Gao, Ranran
name: Zhang, Zemin
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Space Science
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2. Supplementary figures.
Esta Colombia preparada para cumplir con la demanda alimentaria exigida en el 2050.pdf
Creators: name: MABEL VALENCIA
Publisher: name: figshare
Year: 2017
Subjects: subject: 100101 Agricultural Biotechnology Diagnostics (incl. Biosensors)
subject: FOS: Agricultural biotechnology

description: Visibilidad de Colombia como un país potencial para la seguridad alimentaria en el 2050.
George Kennan and the Russian Soul: Issues from the Authorized Kennan Biography by John Lewis Gaddis
Creators: Doctorow, Gilbert
Publisher: name: Columbia University
Year: 2013
Subjects: International relations
Diplomatic relations
Cold War (1945-1989)

description: George Frost Kennan is probably best known as the author of the “containment policy” which served as the overarching principle informing U.S. foreign policy during the Cold War. With the collapse of the Soviet empire in Eastern Europe in 1989 and the demise of the Soviet Union itself in 1991, very much along the lines that Kennan had foreseen when launching his policy recommendations in 1946, one might assume that the master's life and thoughts would be of consequence today only to historians of the Cold War, like his authorized biographer John Gaddis. However, a second abiding concern of Kennan throughout his career was to defend the principle of interest-based foreign policy, or Realpolitik, as opposed to the moralistic-legalistic approach to policy formulation which prevailed in the American foreign policy community of his day. Since that very same object of Kennan's scorn, Wilsonian idealism, has become even further entrenched in the Washington of our day, Kennan's life and thoughts are also directly relevant to current politics in America. Moreover, as I will set out in this essay, there are issues surrounding Kennan's career in government service that are instructive as regards today's practices of recruiting and promoting top level planners and implementers of foreign policy. For these reasons, it is very good that in his biography of Kennan which came out last year Gaddis does not let his own persona intrude —put simply, he does not get in the way. He has thereby facilitated a growing discussion about Kennan in the professional community.
Giusto Lo Dico
Creators: Cavallo, Jo Ann
Publisher: name: Columbia University
Year: 2012
Subjects: Biography
Romance literature
Art

description: Giusto Lo Dico was a prose writer born in Palermo and has been a household name in Sicilian popular culture since the late 1850s, heralded as the ultimate authority in matters concerning Charlemagne and his knights. His towering reputation stems from his authorship of La storia dei paladini di Francia cominciando da Milone conte d’Anglante fino alla morte di Rinaldo [The History of the Paladins of France from Count Milone of Anglante to the Death of Rinaldo], which became the foundational text form Sicilian puppet theater in the following decades.
Global Indigenous Youth: Through Their Eyes - Acknowledgements, About the Cover Art, Forward
Creators: Angel, Dali
Lopez-Carmen, Victor A.
Stamatopoulou, Elsa
Poulsen, Seqininnguaq Lynge
Wickramanayake, Jayathma
Publisher: name: Columbia University
Year: 2019
Subjects: Human rights
Indigenous peoples
Indigenous youth

description: The Acknowledgements, About the Cover Art, and Forward for Global Indigenous Youth: Through Their Eyes. In this book, we, Indigenous Youth, explore the human rights challenges that we face nowadays, including how we view our identity as Indigenous youth in the face of modernization and globalization.