cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Protective effects of selenium on cadmium neurotoxicity
Creators: name: Branca, Jacopo
name: Morucci, Gabriele
name: Pacini, Stefania
name: Gulisano, Massimo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Selenium; cadmium; neurons

description: Prolonged exposure to Cadmium may cause serious toxic effects due to its accu- mulation on both central and peripheral nervous systems. Cadmium could be uptak- en from the nasal mucosa via the olfactory pathways and gain direct access into the nervous system circumventing the blood-brain barrier. However, mechanisms under- lying the cadmium uptake and neurotoxicity remain not completely understood. Oxidative damage, interference with calcium-, copper- and zinc-dependent processes, dysregulation of cell repair mechanisms, estrogen-like effects, and epigenetic modifi- cations may be considered mechanisms for cadmium-induced neurotoxicity [1]. Our previous data demonstrated that zinc chloride counteracts the toxic effects of cadmium chloride (CdCl2) on human neurons in vitro [2]. Thus, in this study we evaluate the efficacy of Sodium Selenite (Na2SeO3) in preventing and/or counteracting the damages induced by exposure to cadmium chloride on a human neuronal cell line. In this study we treated SH-SY5Y human neurons with different sub-toxic concentrations of CdCl2 for 24 h with and without a 24 h pre-treatment with Na2SeO3. Cell viability, morphological modifications, and protein expression of specific neuronal plasticity and apoptosis (Gap43 and caspase 3) markers were evaluated. Our results suggest that toxic effects of CdCl2 can be prevented and reverted by Na2SeO3 suggesting a role for selenium compounds in protecting neuronal cells and rebuilding the complex network connections.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Primo piano primitivo di Ultima Thule
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2019

Un’immagine senza precedenti del corpo celeste più lontano mai visitato da un oggetto costruito dall’uomo. La sonda New Horizons è stata in grado di scrutare l'oggetto da vicino, rilevando le caratteristiche superficiali di Mu69. L’immagine si è meritata la copertina della rivista Science
Domain walls from ten dimensions
Creators: name: Haack, Michael
name: Lust, Dieter
name: Martucci, Luca
name: Tomasiello, Alessandro
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We write down the general conditions for N=1 supersymmetric four-dimensional domain walls, deriving them from a ten-dimensional point of view using generalized complex geometry. In cases where the compactification allows for a truncation to a finite number of fields, we make contact with a four-dimensional effective description. In the context of the AdS/CFT correspondence, the equations can be applied to renormalization-group flows of three-dimensional field theories. We allow for the presence of explicit brane sources and show how supersymmetry restricts their location in a natural way.
description: 31 pages. v2: references added, acknowledgments updated, typo fixed
Ultrastructural features of human sperm cells cryopreserved by different methods
Creators: name: Omes, Claudia
name: Icaro Cornaglia, Antonia
name: Riva, Federica
name: Savio, Monica
name: Mazzini, Giuliano
name: Marchetti, Anna Lisa
name: Sanarica, Chiara
name: Tinelli, Carmine
name: Farina, Aurora
name: Calligaro, Marco Alberto
name: Nappi, Rossella Elena
name: Casasco, Andrea
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Cryopreservation of human spermatozoa has been recognized as a key strategy for management of male fertility. Nevertheless, current protocols of sperm freezing are neither optimal nor standardized between different labs (1). In this study we compare the ultrastructural features of human normospermic sperm samples (according to WHO parameters 2010) from 5 different freezing techniques in order to identify the best methods of cryopreservation. After informed con- sent, 21 normospermic patients (from the Medically Assisted Procreation PMA Center of the Fondazione IRCCS Policlinico San Matteo in Pavia) were recruited and both traditional and improved analysis of sperm quality were applied, in order to define critical steps of cryopreservation. Cryopreservation of human spermatozoa has been related to decreased motility associated with impaired velocity and viability of sperm pre-freeze and post-thaw. For all applied methods there was a significant reduction of progressive and total motility (P) as a result of freezing. To investigate ultrastructural details, 5 additional cryopreserved samples by the best two freezing methods were analyzed with elec- tron microscopy (TEM). Preliminary data showed the minimal differences between the protocols, with a large number of queues detached and large quantities of cyto- plasmic debris after of the first protocol. Spermatozoa appear to be better preserved in the second analyzed method, despite both procedures induced deteriorations at ultrastructural level (2). Other non-routine analysis will be performed to determine whether the cooling time to +4°C may affect the procedure; Comet Assay (to assess the degree of sperm DNA fragmentation) (3) and flow cytometry (to study light scat- ters patterns and membrane integrity) (4) will be applied.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Application of Q-methodology for identifying factors of acceptance of spatial planning instruments
Creators: name: Sudau, Manuel
name: Celio, Enrico
name: Grêt-Regamey, Adrienne
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: Worldwide, urbanization leads to increased pressure on prime agricultural land with irreversible impacts on the provision of life-supporting services such as food and drinking water production or habitat for plants and animals. As a basis for designing new policy instruments to protect soil resources, we applied Q-methodology to assess factors that influence the acceptance or rejection of such instruments. Using an online survey and interviews, we identified different social perspectives and their respective argumentation patterns. The results show that effect on people, institutional embeddedness, trust in the acting institutions, and the overall understanding of the instrument are the most important factors for the acceptance of policy instruments fostering the sustainable use of soil resources. During the interviews, idealistic and fact-based arguments were more important than person-based arguments. Based on our results, communication strategies in the policy-making process can be improved and tailored to the identified characteristics of the social perspectives.
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title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¾ÑÐ°ÑÐ¾Ð², Ð®ÑÐ¸Ð¹
name: Ð¯ÐºÐ¾Ð²Ð»ÐµÐ², ÐÐ°Ð»ÐµÑÐ¸Ð¹
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ ÐÐ¾Ð»Ð¸ÑÐµÑÐ½. ÑÐ½-ÑÐ°
Year: 2004
Subjects: Ð¤Ð¸Ð»ÑÑÑÑ ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ
Ð­Ð»ÐµÐºÑÑÐ¾ÑÐ½ÐµÑÐ³ÐµÑÐ¸ÐºÐ°
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description: ÐÐµÑÐ°ÑÐ°ÐµÑÑÑ Ð¿Ð¾ ÑÐµÑÐµÐ½Ð¸Ñ ÑÐµÐ´Ð°ÐºÑÐ¸Ð¾Ð½Ð½Ð¾-Ð¸Ð·Ð´Ð°ÑÐµÐ»ÑÑÐºÐ¾Ð³Ð¾ ÑÐ¾Ð²ÐµÑÐ° Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ°.
Ngc 4485 messa a nudo da Hubble
Creators: Giuseppe Fiasconaro
Publisher: name: Media Inaf
Year: 2019

Immortalata dalla Wide Field Camera 3 del telescopio spaziale di Nasa ed Esa, è ciò che resta della piccola galassia dopo lo scontro titanico, avvenuto milioni di anni fa, con la galassia a spirale barrata Ngc 4490
Nuclear localization and new isoforms detection give new insights on Hsp10 functions in normal and cigarette smoke-stressed lung cells
Creators: name: Anzalone, Rita
name: Corrao, Simona
name: Lo Iacono, Melania
name: Corsello, Tiziana
name: Russo, Eleonora
name: Saieva, Salvatore
name: Trapani, Maria Elena
name: Di Stefano, Antonino
name: Balbi, Bruno
name: Farina, Felicia
name: Zummo, Giovanni
name: De Macario, Everly Conway
name: Macario, Alberto J.L.
name: Cappello, Francesco
name: La Rocca, Giampiero
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Hsp10; lung cells; COPD; cigarette smoke; nuclear localization

description: Heat-shock protein (Hsp)10 is the co-chaperone for Hsp60 inside mitochondria, but it also resides outside the organelle. Variations in its levels and intracellular dis- tribution have been documented in pathological conditions, e.g. cancer and chronic obstructive pulmonary disease (COPD). Cigarette smoke (CS) is a potent stressor for the respiratory system, but its effects on the expression, function, and cellular locali- zation of mitochondrial chaperonins are still largely unknown. We studied in vivo (airways biopsies) the localization of Hsp10 and Hsp60 in patients (smokers and non-smokers) affected by mild-moderate COPD, and charac- terized the effects of non-lethal doses of CS extract (CSE) on the expression of these molecules in two human cell lines: lung fibroblasts (HFL-1) and bronchial epithelial cells (16HBE). We applied various in vitro methods: IHC, subcellular fractionation analyses (SFA), western blotting (WB), ICC, transmission electron microscopy (TEM) immunogold, chromati protein extracts (CPE), as well as 2D-gel based proteomics analyses. Bioinformatics was used to gather structural in silico data. IHC showed that Hsp10 occurred in nuclei of epithelial and lamina propria cells of bronchial mucosa from non-smokers and smokers. ICC, SFA, and WB showed that 16HBE and HFL-1 cells featured nuclear Hsp10, before and after CSE exposure; TEM immunogold further confirmed this observation. Proteomics data showed that CSE stimulation did not increase the levels of Hsp10 but did elicit qualitative changes as indicated by molecular weight and isoelectric point shifts. Bioinformatics analyses indicated that Hsp10 can localize in extramitochondrial sites, such as the nucleus, even if Hsp10 lacks known DNA-binding motifs or nuclear import signals. Hsp10 nuclear levels increased after CSE stimulation in HFL-1, indicating cytosol to nucleus migration, and although Hsp10 did not bind DNA, it bound a DNA-associated protein as suggested by CPE/gel retardation experiments. Data reported here indicate that in human cells of the respiratory mucosa there are at least three different intracellular locales for Hsp10: mitochondrial, nuclear, and cyto- solic. Further experiments are en route for the definition of the mechanisms underlying the transfer of Hsp10 to the nucleus and other cellular/extracellular compartments. This work was supported by grants from University of Palermo (FFR 2012) to GLR.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Guida di sopravvivenza per esopianeti
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2019

I piccoli pianeti rocciosi hanno maggiori probabilità di sopravvivere quando la loro stella diventerà una nana bianca. La maggior parte dei pianeti sarà fagocitata dalla stella morente, ma alcuni potrebbero essere spinti verso l'esterno e riuscire a cavarsela. Lo studio è stato pubblicato su Mnras
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐ¸ÑÑÐµÐ¼Ñ Ð°Ð½ÑÐ¸ÐºÑÐ¸Ð·Ð¸ÑÐ½Ð¾Ð³Ð¾ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð½Ð° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: Ð¡ÐµÑÐ³Ð¸Ð½Ð°, ÐÐ»Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð°Ð½ÑÐ¸ÐºÑÐ¸Ð·Ð¸ÑÐ½Ð¾Ðµ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ
Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
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ÑÑÐ½ÐºÑÐ¸Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ

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Tre premi astronomici a giovani ricercatori
Creators: Redazione Media Inaf
Publisher: name: Media Inaf
Year: 2019

Oggi pomeriggio, al termine della terza giornata del congresso annuale della Società astronomica italiana, sono stati consegnati i premi intitolati a “Pietro Tacchini”, “Guido Horn D’Arturo” e “Giuseppe Lorenzoni”
title: ÐÐ¸Ð·Ð½ÐµÑ-Ð¿Ð»Ð°Ð½ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÑÐµÑÑ ÑÑÐ»ÑÐ³ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½Ð¾Ð³Ð¾ ÐºÐ»ÑÐ±Ð°)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
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Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð±Ð¸Ð·Ð½ÐµÑ-Ð¿Ð»Ð°Ð½
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ปัจจัยที่มีผลต่อการเลือกซื้อผ้าฝ้ายปั่นมือย้อมสี : กรณีศึกษา กลุ่มผ้าฝ้ายปั่นมือย้อมสีธรรมชาติ ตูบแก้วมา บ้านนาเดา อำเภอเสริมงาม จังหวัดลำปาง
Creators: name: ณัฐพงษ์ ศรีใจวงศ์
Publisher: name: คณะวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์
Year: 2023
Subjects: กลยุทธ์ทางการตลาด
ผ้าฝ้ายทอมือ
ปัจจัยส่วนประสมทางการตลาด

description: วารสารวิจัยวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์, 7, 1, 71-84
An Overview of Women Candidate Performance in Papua New Guinea Elections
Creators: name: Meki, Theresa
Publisher: name: Canberra, ACT : Coral Bell School of Asia Pacific Affairs, College of Asia and the Pacific, The Australian National University
Year: 2015

description: Despite the increasing number of women contesting in national elections in Papua New Guinea, and the excitement of having three women elected in the 2012 elections, women’s overall performance in proportion to their male counterparts remains somewhat stagnant. In this In Brief, I examine election data in reference to how Papua New Guinean women candidates fare at the polls and highlight some challenges for women contesting in the coming 2017 elections.
Phragmites australis subsp. australis
Creators: name: Cardona, Àngel Manuel Hernández
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Poaceae
Phragmites
Phragmites australis
Phragmites australis (cav.) steudel subsp. australis

description: Phragmites australis (Cav.) Steudel subsp. australis
(canyís). Planta subcosmopolita. Creix en estanys, basses, aiguamolls i cursos d’aigua. És poc o molt abundant al riu Ripoll i a quasi tots els torrents i rieres (Fig. 8).
description: Published as part of Cardona, Àngel Manuel Hernández, 2022, Catàleg actualitzat i claus d'identificació de les gramínies de Sant Llorenç del Munt i l'Obac (Barcelona), pp. 64-86 in Nemus 12 on page 73, DOI: 10.5281/zenodo.12170499
Status Report on the United Nations Basic Space Science Initiative (UNBSSI)
Creators: name: Haubold, H. J.
name: Gadimova, S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Since 1990, the UN Programme on Space Applications leads the United Nations Basic Space Science Initiative by contributing to the international and regional development of astronomy and space science through annual UN/ESA/NASA/JAXA workshops on basic space science, International Heliophysical Year 2007, and the International Space Weather Initiative. Space weather is the conditions on the Sun and in the solar wind, magnetosphere, ionosphere and thermosphere that can influence the performance and reliability of space-borne and ground-based technological systems and can endanger human life or health. The programme also coordinates the development of IHY/ISWI low-cost, ground-based, world-wide instrument arrays. To date, 14 world-wide instrument arrays comprising approximately 1000 instruments (GPS receivers, magnetometers, spectrometers, particle detectors) are operating in more than 71 countries. The most recent workshop was hosted by the Republic of Korea in 2009 for Asia and the Pacific. Annual workshops on the ISWI have been scheduled to be hosted by Egypt in 2010 for Western Asia, Nigeria in 2011 for Africa, and Ecuador in 2012 for Latin America and the Caribbean.
description: 8 pages
title: ÐÑÐ°ÐºÑÐ¸ÐºÑÐ¼ Ð¿Ð¾ ÑÐµÐ¾ÑÐ¸Ð¸ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ: Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð· Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼
Creators: name: ÐÐ¾Ð½Ð¾Ð¼Ð°ÑÐµÐ², ÐÐ»ÐµÐºÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐÐ¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ¸ÑÑÐµÐ¼Ñ
ÐÐ¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
ÐÐ²ÑÐ¾Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ðµ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ðµ

description: ÐÐ¾Ð½ÑÐ¿ÐµÐºÑ Ð´Ð¾Ð¿Ð¾Ð»Ð½Ð¸ÑÐµÐ»ÑÐ½ÑÑ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð² Ð´Ð»Ñ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð·Ð°Ð½ÑÑÐ¸Ð¹ Ð¿Ð¾ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ðµ Â«Ð¢ÐµÐ¾ÑÐ¸Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÂ», ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²ÑÑÑÐ¸Ñ Ð¤ÐÐÐ¡ ÐÐÐ Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÐ¼ 27.03.03 Ð¸ 09.03.02. Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ Ð²Ð¾Ð¿ÑÐ¾ÑÑ, ÐºÐ°ÑÐ°ÑÑÐ¸ÐµÑÑ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼ Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð¸Ñ ÐºÐ°ÑÐµÑÑÐ²ÐµÐ½Ð½ÑÑ ÑÐ²Ð¾Ð¹ÑÑÐ² â Ð²Ð½Ð¸Ð¼Ð°Ð½Ð¸Ðµ ÑÐ´ÐµÐ»ÐµÐ½Ð¾ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐ¼ ÐºÐ¾Ð½ÑÐµÐ¿ÑÐ¸ÑÐ¼, Ð¼Ð¾Ð´ÐµÐ»ÑÐ¼ Ð¸ Ð¼ÐµÑÐ¾Ð´Ð°Ð¼, Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÐµÐ¼ÑÐ¼ Ð´Ð»Ñ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð¾Ð±ÑÐµÐºÑÐ¾Ð² Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼, Ð¸Ð·ÑÑÐµÐ½Ð¸Ñ ÑÐ²Ð¾Ð¹ÑÑÐ² ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÐ¸, Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¾Ð¹ ÑÑÑÐ¾Ð¹ÑÐ¸Ð²Ð¾ÑÑÐ¸, Ð°Ð»Ð³ÐµÐ±ÑÐ°Ð¸ÑÐµÑÐºÐ¸Ñ Ð¸ Ð³ÐµÐ¾Ð¼ÐµÑÑÐ¸ÑÐµÑÐºÐ¸Ñ ÑÑÑÑÐºÑÑÑ, Ð¿ÑÐ¸Ð¼ÐµÐ½ÑÐµÐ¼ÑÑ Ð´Ð»Ñ ÑÐµÑÐµÐ½Ð¸Ñ ÑÑÐ¸Ñ Ð·Ð°Ð´Ð°Ñ. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ Ð¿ÑÐ¸Ð¼ÐµÑÑ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð´Ð°Ð½Ð½ÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð² Ðº Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð·Ñ Ð»Ð¸Ð½ÐµÐ¹Ð½ÑÑ Ð¸ Ð½ÐµÐ»Ð¸Ð½ÐµÐ¹Ð½ÑÑ Ð´Ð¸Ð½Ð°Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐ¸ÑÑÐµÐ¼. ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ Ð´Ð¸ÑÑÐ¸Ð¿Ð»Ð¸Ð½Ñ Â«Ð¢ÐµÐ¾ÑÐ¸Ñ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÂ» Ð¸ Â«Ð¡Ð¸ÑÑÐµÐ¼Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÂ» Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸ÑÐ¼ 27.03.03 Ð¸ 09.03.02.
การสื่อสารการตลาดที่ส่งผลต่อกระบวนการตัดสินใจซื้อผลิตภัณฑ์เครื่องสำอางออร์แกนิค
Creators: name: สุณิสา บุญรอด
Publisher: name: คณะวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์
Year: 2023
Subjects: ผลิตภัณฑ์เครื่องสำอางออร์แกนิค
การสื่อสารการตลาด
กระบวนการตัดสินใจซื้อ

description: วารสารวิจัยวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์, 7, 1, 85-97
Sedici maggio, Giornata internazionale della luce
Creators: Rossella Spiga
Publisher: name: Media Inaf
Year: 2019

È oggi il giorno in cui si celebra nel mondo l’importanza della luce in tutte le sue implicazioni e delle tecnologie a essa correlate. La data è stata scelta per ricordare l’anniversario della prima realizzazione artigianale di un laser al cristallo di rubino
A Review of AGB Mass Loss Imaging Techniques
Creators: name: Marengo, Massimo
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Circumstellar imaging, across the electromagnetic spectrum, allows to derive fundamental diagnostics for the physics of mass loss in the AGB phase. I review the current status of the field, with particular emphasis on the techniques that provide the strongest constraints for mass loss modeling efforts.
description: accepted for publication in the Publications of the Astronomical Society of Australia
Suppression of soliton collapses, modulational instability, and rogue-wave excitation in two-Lévy-index fractional Kerr media
Creators: name: Zhong, Ming
Publisher: name: Zenodo
Year: 2023

description: This code is used to address formation, propagation, interaction as well as exciation of solitons and rogue waves in one-dimensional fractional nonlinear Schodinger equation with two-Levy index.
title: Perceived experiences of preparing accounting students with digital skills for the workplace
title: An exploratory grounded approach study at a newly formed Technological University in Ireland
titleType: Subtitle
Creators: name: Gorman, Geraldine
Publisher: name: Lancaster University
Year: 2024

description: Accounting education has been criticised for ill-equipping graduates for

 professional employment, with calls for accounting students to have a
 broader

 range of skills, particularly digital skills on entering the workplace.
 Digital skills

 are an important employability skill, yet employers repeatedly state that

 accounting graduates entering the workplace do not have the necessary
 digital

 skills to carry out their roles effectively. Accounting educators in
 higher

 education have differing views on the level of importance placed on
 digital skills

 covered in accounting programmes. The differing views between the level of

 skills employers expect and what accounting educators are covering in
 higher

 education are currently misaligned. Although a certain degree of
 misalignment

 is anticipated, this gap is expanding to the extent of resembling a
 “gaping hole”.

 This study uses a grounded approach, an approach not used in previous

 studies in this area, to analyse data from the most influential
 stakeholders in

 enacting change in higher education accounting curriculums – teaching
 staff on

 programmes. Using this approach allowed for a comprehensive answering of

 the research questions where no predetermined outcomes were anticipated,

 and common themes emerged from the data during the analysis process.

 This study highlights the challenges of implementing digital skills in
 accounting

 programmes, with the most influential factor in the process being the
 pressure

 on staff to obtain professional exemptions from professional accounting
 bodies. Other challenges were also identified in integrating digital
 skills into higher

 education accounting education, such as the lack of resources and
 institutional

 support, uneven distribution of digital skills modules in course design ie
 front

 loading modules in Year 1 of programmes, and limitations in including work

 placement on programmes. It concludes that it is necessary to scrutinise
 the

 connections between higher education institutions, professional accounting

 bodies, and employers. Presently, professional accounting bodies wield

 significant influence in higher education, while employers’ engagement is

 lacking. This research proposes that establishing a more equitable and

 organised collaboration among these three entities in a formal manner,
 would

 enhance these relationships in the future and foster more sustainable

 outcomes. This collaboration would subsequently boost flexibility and
 create

 space for the integration of essential digital skills for accounting
 students who

 are entering today's workforce.
The effect of circuit training on the physical fitness of grade 5 girls
Creators: name: Brown, Annie May
Publisher: name: University of British Columbia
Year: 2011

description: The purpose of this study was to determine the effect of a circuit training programme on the physical fitness of grade 5 girls. Two classes of grade 5 girls at Kerrisdale Elementary School, Vancouver, British Columbia, participated in this experiment. All students within these two classes were given the AAHPER Youth Fitness Test -modified pull-up, sit-up, shuttle run, standing broad jump, 50-yard dash, softball throw for distance, 600-yard run-walk. One class was selected at random to be the Experimental Class, the second class to be the Control Class. The Experimental Class participated in a ten-minute circuit training programme at the beginning of each lesson for eight weeks. The remainder of the lesson was devoted to the regular physical education programme. The Control Class participated in the regular physical education programme for the eight weeks. At the end of the eight weeks both groups were re-tested on the AAHPER Youth Fitness Test. Improvements were measured statistically within each group and a comparison of the improvements was made between the groups both on separate test items and on a total physical fitness score. In addition, a coefficient of correlation was calculated between the gains of the Experimental Class and their physical education teacher's rating of student "co-operativeness". The Experimental Class showed a significant gain in performance in the modified pull-up, sit-up, shuttle run, standing broad jump, Softball throw for distance and 600-yard run-walk. The Control Class showed a significant gain in performance in the sit-up, shuttle run, standing broad jump, Softball throw for distance and 600-yard run-walk. The Control Class made significantly greater gains than the Experimental Class in the shuttle run. Both groups made statistically, significant gains in the total physical fitness scores. However, there was no statistically significant difference between these mean gains. There was some relationship, though low, between the gains made by the Experimental Class and the teacher rating of student "co-operativeness". The conclusion resulting from this study was that a physical education programme for grade 5 girls which includes a ten-minute circuit training programme, does improve their physical fitness, as measured by the AAHPER Youth Fitness Test. The data of this study also should, be interpreted to indicate that programmes other than circuit training may be equally effective in increasing physical fitness as measured by the AAHPER Youth Fitness Test.
A gauge/gravity duality model for gauge theory thermodynamics
Creators: name: Alanen, J.
name: Kajantie, K.
name: Suur-Uski, V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study a gauge/gravity model for the thermodynamics of a gauge theory with one running coupling. The gravity side contains an ansatz for the metric and a scalar field, on the field theory side one starts by giving an ansatz for the beta function describing the scale dependence of the coupling. The model is based on relating the scale to the extra dimensional coordinate and the beta function to the gravity fields, thereby also determining the scalar field potential. We study three different forms of beta functions of increasing complexity and give semianalytic solutions describing first order or continuous transitions.
description: 19 pages, 10 figures
การจัดการตลาดท่องเที่ยวเชิงประสบการณ์ของหมู่บ้านทอผ้าในจังหวัดบุรีรัมย์
Creators: name: สุรีรัตน์ เครือบคนโท
Publisher: name: คณะวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์
Year: 2023
Subjects: การจัดการตลาด
การตลาดท่องเที่ยวเชิงประสบการณ์
หมู่บ้านทอผ้า

description: วารสารวิจัยวิทยาการจัดการ มหาวิทยาลัยราชภัฏสุรินทร์, 7, 1, 98-112
Stellar mass ejections
Creators: name: Jardine, M.
name: Donati, J. -F.
name: Gregory, S. G.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It has been known for some time now that rapidly-rotating solar-like stars possess the stellar equivalent of solar prominences. These may be three orders of magnitude more massive than their solar counterparts, and their ejection from the star may form a significant contribution to the loss of angular momentum and mass in the stellar wind. In addition, their number and distribution provide valuable clues as to the structure of the stellar corona and hence to the nature of magnetic activity in other stars. Until recently, these "slingshot prominences" had only been observed in mature stars, but their recent detection in an extremely young star suggests that they may be more widespread than previously thought. In this review I will summarise our current understanding of these stellar prominences, their ejection from their stars and their role in elucidating the (sometimes very non-solar) behaviour of stellar magnetic fields.
description: 10 pages, 6 figures
Nuovo enigma dal lato nascosto della Luna
Creators: Maura Sandri
Publisher: name: Media Inaf
Year: 2019

Le analisi spettroscopiche condotte dal lander cinese Chang'E-4 nel Polo Sud-Aitken della Luna evidenziano tracce di olivina, invece del contenuto abbondante che si aspettavano gli scienziati. Un maggior quantitativo di olivina è stato trovato nei campioni provenienti da impatti più profondi. I risultati della ricerca sono stati pubblicati oggi su Nature
title: Comité permanente sobre el derecho de marcas, dibujos y modelos industriales e indicaciones geográficas :
title: Informe aprobado por el comité.
titleType: Subtitle
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 0

description: El Comité Permanente sobre el Derecho de Marcas, Diseños Industriales e Indicaciones Geográficas (denominado en adelante “el Comité Permanente” o “el SCT”) celebró su decimocuarta sesión del 18 al 22 de abril de 2005.
Generalized CP symmetries and special regions of parameter space in the two-Higgs-doublet model
Creators: name: Ferreira, P. M.
name: Haber, Howard E.
name: Silva, Joao P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider the impact of imposing generalized CP symmetries on the Higgs sector of the two-Higgs-doublet model, and identify three classes of symmetries. Two of these classes constrain the scalar potential parameters to an exceptional region of parameter space which respects either a Z_2 discrete flavor symmetry or a U(1) symmetry. We exhibit a basis-invariant quantity that distinguishes between these two possible symmetries. We also show that the consequences of imposing these two classes of CP symmetry can be achieved by combining Higgs Family symmetries, and that this is not possible for the usual CP symmetry. We comment on the vacuum structure and on renormalization in the presence of these symmetries. Finally, we demonstrate that the standard CP symmetry can be used to build all the models we identify, including those based on Higgs Family symmetries.
description: 20 pages, RevTex, version to appear in PRD
Beresheet: la Nasa avvista il sito dello schianto
Creators: Eleonora Ferroni
Publisher: name: Media Inaf
Year: 2019

Tra i numerosi crateri presenti nella zona di Mare Serenitatis, uno potrebbe essere riconducibile all'impatto della sonda avvenuto lo scorso 11 aprile. Una missione ambiziosa, forse troppo, finita tra la polvere lunare
Gonadotropin-releasing hormone induces biliary proliferation by both paracrine and autocrine mechanisms
Creators: name: Mancinelli, Romina
name: Venter, Julie
name: Glaser, Shannon
name: Alpini, Gianfranco
name: Pannarale, Luigi
name: Onori, Paolo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Biliary epithelium; GnRH; neuroendocrine peptides; cholestatic diseases

description: During cholestatic liver disease, there is dysregulation in the balance between biliary growth and loss. In bile ductligated (BDL) rats, this balance is modulated by neuroendocrine peptides via autocrine/paracrine pathways (1). Gonadotropinreleasing hormone (GnRH) is a trophic peptide hormone that modulates reproduc- tive function and proliferation in many cell types (2). We evaluated the autocrine role of GnRH in the regulation of cholangiocyte growth. The expression of GnRH receptors was evaluated in a normal mouse cholangiocyte cell line (NMC), sham and BDL rats. The effect of GnRH administration was evaluated in normal rats and in NMC. GnRH-induced biliary proliferation was evaluated by changes in intrahepatic bile duct mass (IBDM) by CK19 specific staining, the expression of proliferation and function markers. The expression and secretion of GnRH in NMC and isolated cholangiocytes was assessed. GnRH receptor subtypes GnRHR1 and GnRHR2 were expressed in biliary epithelium. Treatment with GnRH increased IBDM as well as proliferation and function markers in cholangiocytes. Transient knockdown and pharmacologic inhibition of GnRHR1 in NMC decreased proliferation. BDL cholangiocytes had increased expression of GnRH compared with normal rats, accompanied by increased GnRH secretion. In vivo and in vitro knockdown of GnRH decreased intrahepatic bile duct mass/cholangiocyte proliferation and fibrosis. GnRH secreted by cholangiocytes promotes biliary proliferation via an autocrine pathway. Disruption of GnRH/ GnRHR signaling may be important for the management of cholestatic liver diseases.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
title: Symptoms and illness : The cognitive organisation of disorder
Creators: name: Locker, David
Publisher: name: University of Kent
Year: 2023

description: The research reported here is largely concerned with the theoretical development and empirical elaboration of a sociological concept of illness and a theory of social action related to that concept which would contribute to the understanding of illness and illness behaviour. I took this to be of relevance since the concept of illness employed by medical sociologists has been inadequate and the study of illness behaviour characterised by an absence of explicit sociological theory. That is, by a general failure to specify and systematically apply a set of assumptions regarding the nature of social phenomena and social action. As I argued in 1975 (1), and as others have since argued (2), the social problem of why people do and do not use health services has been confused with the sociological problem posed by illness and illness behaviour. This confusion is rooted in the pragmatic origins of medical sociology, its patronage by medicine and its adoption of the epidemiological model of science. The main theoretical assumption employed here is that illness is a social phenomenon constituted by the meanings actors construct in making sense of observed or experienced events. A related and equally important assumption is that the meanings imputed to these events have an influence on how they are subsequently managed. These ideas are derived from symbolic interactionism and labelling theory. For the most part, medical sociologists have ignored meanings; illness has been treated as an objective entity and causal explanations of illness behaviour offered whose implicit theories of action do not call for attention to meanings. The above assumptions have also been used to argue that disease and illness are distinct phenomena and must be studied in ways V which take account of their individual nature. While some medical sociologists have drawn this distinction between illness and disease, they have rarely followed up its implications in terms of theory or research. One reason for this is that the conceptual separation involved is usually asserted rather than having its origins in explicit propositions about the nature of social reality. The focus of the study reported here is on meanings. It aims to identify and describe some of the cognitive and interactional processes by means of which they are constructed. The methodological stance I adopt has been influenced by the sociological naturalists and the writings of the ethnomethodologists. Consequently, language, categorisation and social order are key and recurrent themes. It is then both sociology of illness and sociology of everyday life.
Supplementary files for the paper "Raising the analytical capacity of political science with root cause analysis."
Creators: name: Harich, Jack
name: Koloffon Rosas, Montserrat
Publisher: name: figshare
Year: 2025
Subjects: classificationCode: 440899
subject: Political science not elsewhere classified

description: The paper used a simulation model for analysis and a spreadsheet for study data. Here is what the files contain:DuelingLoops_Dem_English.html - A long table describing the details of the system dynamics model.DuelingLoops_Dem.mdl - The system dynamics model. We used Vensim.ModelDescription.docx - Describes the model and simulation runs.StudyResultsData.xlsx - Contains the raw data and statistical analysis for the Truth Literacy Training study.
First Tests of Gaseous Detectors Made of a Resistive Mesh
Creators: name: Oliveira, R.
name: Peskov, V.
name: Pietropaolo, F.
name: Picchi, P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: We describe here various detectors designs: GEM type, MICROMEGAStype, PPACtype as well as cascaded detectors made of a resistive mesh manufactured from a resistive Kapton foil, (20 microns thick, resistivity a few MOhm per square) by a laser drilling technique. As in any other micropattern detectors the maximum achievable gas gain of these detectors is restricted by the Raether limit, however, the resistive mesh makes them and the front end electronics fully spark protected. This approach could be an alternative or complimentary to the ongoing efforts in developing MICROMEGAS and GEMs with resistive anode readout plates and can be especially beneficial in the case of micropattern detectors combined with a micropixel-type integrated front end electronics
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÑ Ð½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð¿Ð¾ Ð·Ð°ÑÐ¸ÑÐ°Ð¼ Ð¸ Ð¿ÑÐ¾ÑÐ¸Ð²Ð¾Ð°Ð²Ð°ÑÐ¸Ð¹Ð½Ð¾Ð¹ Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸ÐºÐµ ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸Ð¸ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½ÑÑ Ð½ÑÐ¶Ð´ Ð½Ð° Ð±Ð°Ð·Ðµ ÑÐ¸ÑÑÐ¾Ð²ÑÑ ÑÐµÑÐ¼Ð¸Ð½Ð°Ð»Ð¾Ð²
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: Ð§Ð¸ÑÐºÐ¾Ð², ÐÐ»ÐµÐºÑÐµÐ¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð­Ð»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÑÑÐ°Ð½ÑÐ¸Ð¸
Ð ÐµÐ»ÐµÐ¹Ð½Ð°Ñ Ð·Ð°ÑÐ¸ÑÐ°
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ÑÐ¸ÑÑÐ¾Ð²ÑÐµ ÑÐµÑÐ¼Ð¸Ð½Ð°Ð»Ñ

description: Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÐµÑÑÑ ÑÐµÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ñ Ð ÐÐ Ð¼Ð°Ð»Ð¾Ð¹ ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸Ð¸ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½ÑÑ Ð½ÑÐ¶Ð´ Ð¿ÑÐ¸ Ð·Ð°Ð¼ÐµÐ½Ðµ ÑÐ»ÐµÐºÑÑÐ¾Ð¼ÐµÑÐ°Ð½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐµÐ»Ðµ Ð½Ð° ÑÐ¸ÑÑÐ¾Ð²ÑÐµ ÑÐµÑÐ¼Ð¸Ð½Ð°Ð»Ñ. ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½ ÑÐ°ÑÑÐµÑ Ð¸ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¾ÐºÐ¾Ð² ÐºÐ¾ÑÐ¾ÑÐºÐ¸Ñ Ð·Ð°Ð¼ÑÐºÐ°Ð½Ð¸Ð¹, Ð²ÑÐ±Ð¾Ñ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ°ÑÑÐµÑ ÑÑÑÐ°Ð²Ð¾Ðº Ð·Ð°ÑÐ¸Ñ Ð½Ð° ÑÐ»ÐµÐºÑÑÐ¾ÑÑÐ°Ð½ÑÐ¸Ð¸ ÑÐ¾Ð±ÑÑÐ²ÐµÐ½Ð½ÑÑ Ð½ÑÐ¶Ð´, Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð»Ð¾Ð³Ð¸ÐºÐ¸ ÑÐµÑÐ¼Ð¸Ð½Ð°Ð»Ð° Ð·Ð°ÑÐ¸ÑÑ Ð³ÐµÐ½ÐµÑÐ°ÑÐ¾ÑÐ° Ð¸ ÑÑÐµÐ¼ Ð²ÑÐ¾ÑÐ¸ÑÐ½Ð¾Ð¹ ÐºÐ¾Ð¼Ð¼ÑÑÐ°ÑÐ¸Ð¸. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ð¾ ÑÐµÑÐ½Ð¸ÐºÐ¾-ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¾Ðµ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð²Ð½ÐµÐ´ÑÐµÐ½Ð¸Ñ ÑÐ¸ÑÑÐ¾Ð²ÑÑ Ð·Ð°ÑÐ¸Ñ, ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð²Ð¾Ð¿ÑÐ¾ÑÑ ÑÐµÑÐ½Ð¸ÐºÐ¸ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¸ Ð¸Ñ ÑÐºÑÐ¿Ð»ÑÐ°ÑÐ°ÑÐ¸Ð¸
Natural sesquiterpenes β-caryophyllene and β-caryophyllene oxide as chemopreventive agents for cholangiocarcinoma
Creators: name: Mancinelli, Romina
name: Mammola, Caterina Loredana
name: Mazzanti, Gabriela
name: Di Giacomo, Silvia
name: Di Sotto, Antonella
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Natural sesquiterpenes; beta-caryophyllene; cholangiocarcinoma cells; chemoprevention; che- mosensitizer

description: Cholangiocarcinoma (CCA) represents a particular type of liver cancer originating from the epithelial cells lining the intrahepatic and extrahepatic biliary tree. It is often clinically silent until it becomes an advanced disease with obstructive symptoms and a poor prognosis for patients [1]. In this context, searching for alternative therapeutic strategies becomes a pivotal goal in the battle against liver cancer. In present research, β-caryophyllene (CRY) and β-caryophyllene oxide (CRYO), two natural sesquiterpenes with protective properties [2], have been investigated for their ability to inhibit the growth of the human Mz-ChA-1 cholangiocarcinoma cells from extrahepatic bile ducts and the H69 non-malignant cholagiocytes. The cells were exposed to the test compounds for 24 h, then the cytotoxicity was measured by MTT assay [3]; doxorubicin was included as a standard cytotoxic agents. Both sesquiterpenes reduced the cholangiocytes proliferation. Particularly, CRY produced a marked cytotoxicity in the Mz-ChA-1cells at concentrations lower than that required for CRYO. Surprisingly, the antiproliferative effects produced by both CRY and CRYO were higher than that of the standard doxoru- bicin. In the non-malignant cholangiocytes, in spite of a low cytotoxicity of CRYO, CRY reduced the cell proliferation already at lower concentrations, acting in a similar way to doxorubicin. Being CRYO an epoxide analogue of CRY, the different cytotoxicity found could be due to their structural features and bioavailability. Present results encourage further studies on CRY and CRYO as chemopreventive agents for cholangiocarcinoma. This work was supported by grants from Sapienza University Project 2014. Dr. Antonella Di Sotto was financed by “Enrico and Enrica Sovena” Foundation.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
LightSail 2, il veliero spaziale è pronto al lancio
Creators: Giuseppe Fiasconaro
Publisher: name: Media Inaf
Year: 2019

Il suo lancio è programmato per il mese prossimo, a bordo del lanciatore Falcon Heavy della SpaceX. E la navicella spaziale della Planetary Society è già pronta a partire. La sua missione sarà dimostrare la capacità propulsiva della pressione di radiazione del Sole
D5.1.1 Report on data/information availability and infrastructure/tools requirements
Creators: name: Vilibić, Ivica
name: Partnership, The ECOSS
Publisher: name: Zenodo
Year: 2019

description: Within the frame of the Activity 5.1 Design and implementation of data infrastructure of the project ECOSS, this report aims to identify and analyze existing data infrastructures, portals, observing networks together with specific datasets and spatial information relevant for the project.
description: ECOSS project (Observing System in the Adriatic Sea: oceanographic observations for biodiversity) is an EU 2014–2020 Interreg V-A Italy-Croatia CBC programme (ID number 10042301).