cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Investigation to answer three key questions concerning plant pest identification and development of a practical identification framework
Creators: name: Wayama, Ryosuke
name: Sasaki, Yuki
name: Kagiwada, Satoshi
name: Iwasaki, Nobusuke
name: Iyatomi, Hitoshi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The development of practical and robust automated diagnostic systems for identifying plant pests is crucial for efficient agricultural production. In this paper, we first investigate three key research questions (RQs) that have not been addressed thus far in the field of image-based plant pest identification. Based on the knowledge gained, we then develop an accurate, robust, and fast plant pest identification framework using 334K images comprising 78 combinations of four plant portions (the leaf front, leaf back, fruit, and flower of cucumber, tomato, strawberry, and eggplant) and 20 pest species captured at 27 farms. The results reveal the following. (1) For an appropriate evaluation of the model, the test data should not include images of the field from which the training images were collected, or other considerations to increase the diversity of the test set should be taken into account. (2) Pre-extraction of ROIs, such as leaves and fruits, helps to improve identification accuracy. (3) Integration of closely related species using the same control methods and cross-crop training methods for the same pests, are effective. Our two-stage plant pest identification framework, enabling ROI detection and convolutional neural network (CNN)-based identification, achieved a highly practical performance of 91.0% and 88.5% in mean accuracy and macro F1 score, respectively, for 12,223 instances of test data of 21 classes collected from unseen fields, where 25 classes of images from 318,971 samples were used for training; the average identification time was 476 ms/image.
description: 40 pages, 10 figures
Geology of the Morgan-Henefer Area Morgan and Summit Counties, Utah
Creators: name: Schick, Robert Bryant
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Utah
subject: Morgan County
subject: Summit County
subject: Thesis and dissertation georeferencing project

description: The Morgan-Henefer area described in this report includes about 130 square miles in Townships 3, 4 and 5 north, Ranges 2, 3, and 4 east, Salt Lake Meridian, Morgan and Summit Counties, Utah. (See Plate 4). The area is located 25 miles northeast of Salt Lake City, Utah. Morgan Valley and East Canyon bound the west sides of the area, the Lost Creek and Henefer Valleys bound the east side; Norwood Canyon is the extreme south boundary, and Durst Mountain lies on the north line.
Pregnancies complicated by antiphospholipid antibodies: effect of prednisone on the activated partial thromboplastin time and antiphospholipid antibody levels.
Creators: name: Li-Rommel, Yin
Publisher: name: University of Utah
Year: 2012
Subjects: Prednisone
Pregnancy Complications

description: Lupus anticoagulant is an anti-phospholipid autoantibody which is associated with several adverse pregnancy outcomes including recurrent pregnancy loss, intrauterine fetal death, and intrauterine growth retardation.  Treatment of the mother during pregnancy with prednisone and low-dose aspirin increases the rate of delivering a viable infant.  Furthermore, successful outcome has been associated with "correction" of the prolonged partial thromboplastin time by prednisone.  I studied the effect of prednisone therapy (40-120 mg per day) on the partial thromboplastin time and anti-phospholipid antibody levels in eight pregnant women with lupus anticoagulant and correlated the observed changes with the pregnancy outcome.  In all cases, the partial thromboplastin time declined during the treatment.  Restoration of the partial thromboplastin time to the normal range was shown in six patients, of whom three had living infants and three had pregnancy losses.  The anti-phospholipid antibodies were detected by an enzyme-linked immunoabsorbant assay.  In two of five patients who had living infants, the antibody levels returned to normal range at the end of treatment, but the remained abnormal in three others as well as in three patients with pregnancy losses.  This study demonstrates that although treatment with prednisone increases the successful pregnancy outcome of patients with lupus anticoagulant, the effect of the regimen on the partial thromboplastin time doe not predict the pregnancy outcome.  The effect of prednisone on anti-phospholipid antibody levels is unpredictable and it is difficult to predict the therapeutic efficacy be determining the antibody levels.
Self-Supervision Improves Diffusion Models for Tabular Data Imputation
Creators: name: Liu, Yixin
name: Ajanthan, Thalaiyasingam
name: Husain, Hisham
name: Nguyen, Vu
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: The ubiquity of missing data has sparked considerable attention and focus on tabular data imputation methods. Diffusion models, recognized as the cutting-edge technique for data generation, demonstrate significant potential in tabular data imputation tasks. However, in pursuit of diversity, vanilla diffusion models often exhibit sensitivity to initialized noises, which hinders the models from generating stable and accurate imputation results. Additionally, the sparsity inherent in tabular data poses challenges for diffusion models in accurately modeling the data manifold, impacting the robustness of these models for data imputation. To tackle these challenges, this paper introduces an advanced diffusion model named Self-supervised imputation Diffusion Model (SimpDM for brevity), specifically tailored for tabular data imputation tasks. To mitigate sensitivity to noise, we introduce a self-supervised alignment mechanism that aims to regularize the model, ensuring consistent and stable imputation predictions. Furthermore, we introduce a carefully devised state-dependent data augmentation strategy within SimpDM, enhancing the robustness of the diffusion model when dealing with limited data. Extensive experiments demonstrate that SimpDM matches or outperforms state-of-the-art imputation methods across various scenarios.
description: 10 pages, 5 figures. Accepted by CIKM 2024
Molecular Dynamics Guided Design of Coil-Based Therapeutics
Creators: name: Pendley, Scott Smith
Publisher: name: University of Utah
Year: 2014

description: The coiled-coil is a common protein tertiary structural motif that is composed of two or more alpha helices intertwined together to formed a supercoil. In biological systems, the coiledcoil motif often forms the oligomerization domain of various proteins including DNA binding proteins, structural and transport proteins, and cellular transport and fusion proteins. It was first described by Crick in the 1950s while describing the structure of α-keratin and has since that time been the subject of numerous engineering and mutation studies. This versatile motif has been adapted to a number of nonbiological applications including environmentally responsive hydrogels, crosslinking agents, the construction of self-assembling fibers for tissue engineering, and biosensor surfaces. In this dissertation, we test the applicability of computational methods to understand the underlying energetics in coiled-coils as we apply molecular modeling approaches in the development of pharmaceutics. Two studies are described which test the limits of modern molecular dynamic force fields to understand the structural dynamics of the motif and to use energy calculation methodologies to predict favorable mutations for heterodimer formation and specificity. The first study considers the increasingly common use of fluorinated residues in protein pharmaceutics with regard to their incorporation in coiled-coils. Many studies find that fluorinated residues in the hydrophobic core increase protein stability against chemical and thermal denaturants. Often their incorporation fails to consider structural, energetic, and geometrical differences between these fluorinated residues and their nonfluorinated counterparts. To consider these differences, several variants of Hodges' very stable parallel heterodimer coiledcoil were constructed to examine the effect of salt bridge lengths and geometries with mixed fluorinated and nonfluorinated packed hydrophobic cores. In the second study, we collaborated with an experimental laboratory in the development of a mutant Bcr monomer with designed mutations to increase specificity and binding to the oncoprotein Bcr-Abl for use as an apoptosis inducing agent in chronic myelogenous leukemia (CML) cells. The final chapters of this dissertation discuss challenges and limitations that were encountered using force fields and energetic methods in our attempts to use computational chemistry to model this protein motif.
A multitrait-multimethod investigation of depression and disability in  rheumatoid arthritis
Creators: name: Peck, Judith R.
Publisher: name: University of Utah
Year: 2015
Subjects: Depression
Rheumatoid arthritis
disability

description: A multitrait-multimethod (MtMm) procedure was used to investigate the magnitude of association between disability and depression as well as the convergent and discriminant validity of the Health Assessment Questionnaire (HAQ) Disability Index and two measure of depression, the Beck Depression Inventory (BDI) and the Hamilton Interview Ratting Scale for Depression (HRS-D). Three measures of disability on the HAQ (patient self-report, physical therapist assessment and spouse report) were compared with the two measures of depression in 107 subjects with rheumatoid arthritis (RA).  Pearson correlations among the three disability measures provide strong evidence in support of the convergent validity of the HAQ Disability Index ( r's- . 8 9 t o . 8 5 , D'S < . 0 0 0 ).  Similarly, the correlation between the BDI and the HRS-D ( rs . 6 9 , p. < . 0 0 1 ) provides evidence of convergent validity between the construct of depression and the construct of disability was greater when disease-related somatic difficulties were not included in the measure of depression. The high correlations among the disability measures suggest that subjects report their physical disability on a health status questionnaire with a high level of accuracy.  In addition, the small discrepancies that were observed between self-reported and physical therapist assessed disability were clearly not associated with depression.  This observation was true even though items that may have been endorsed due to disease-related difficulty rather than affective disturbance were included in the BDI score.  However, a measure of helplessness and perceived loss of control, the Rheumatology Attitude Index (RAI), was associated with discrepancy between self-reported and physical therapist assessed disability ( r = . 2 0 , p_
The NCAR/EOL Community Workshop on Unmanned Aircraft Systems for Atmospheric Research - Final Report
Creators: name: H. Vömel
name: B. M. Argrow
name: D. Axisa
name: P. Chilson
name: S. Ellis
name: M. Fladeland
name: E. W. Frew
name: J. Jacob
name: M. Lord
name: J. Moore
name: S. Oncley
name: G. Roberts
name: S. Schoenung
name: C. Wolff
Publisher: name: UCAR/NCAR - Earth Observing Laboratory
Year: 2018

description: The focus of the Community Workshop on Unmanned Aerial Systems for Atmospheric Research was to advance the use of Unmanned Aerial Systems (UAS) on all scales of atmospheric research. The workshop created a forum for discussion and for gathering input from the active UAS research community and those interested in becoming part of that community on highest priority observational needs that may be met by UAS, and on the barriers for use of UAS in atmospheric and atmosphere interface research.
Observational constraints on the equation of state of viscous fluid in $f(R, T)$ gravity
Creators: name: Koussour, M.
name: Altaibayeva, A.
name: Bekov, S.
name: Donmez, O.
name: Muminov, S.
name: Rayimbaev, J.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this paper, we investigate a cosmological model based on viscous $f(R,T)$ gravity as a potential alternative to dark energy. This model incorporates bulk viscosity and is analyzed using an effective equation of state. We consider the simplest specific model, $f(R,T)=R+λT$, where $λ$ is a constant. The exact solution of our viscous $f(R,T)$ cosmological model is derived, and then we use the combined datasets consisting of 31 $H(z)$ data points and 1701 Pantheon+ SNe data points to determine the best-fit values of the model parameters. We find good agreement with observations, particularly at higher redshifts. Our model's behavior, including energy density, pressure with viscosity, effective equation of state, and deceleration parameter, is analyzed. It indicates a shift from decelerated to accelerated phases of the universe's expansion, suggesting that bulk viscosity in the cosmic fluid could effectively generate the negative pressure necessary for cosmic expansion. Finally, we explore statefinder diagnostics to differentiate between various dark energy models, revealing that our model resides in the quintessence region.
description: Physics of the Dark Universe published version
Alpha-decay from $^{44}$Ti: Microscopic alpha half-life calculation using normalized spectroscopic factor
Creators: name: Dassie, A. C.
name: Betan, R. M. Id
Publisher: name: arXiv
Year: 2024
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The microscopic description of alpha decay from the nucleons' degree of freedom involves a two-step process. The first consists of the clusterization of neutron and proton pairs; the second involves the tunneling process. A robust protocol for calculating the normalized spectroscopic factor, as defined by Fliessbach, and its error is established and used for calculating the alpha-width for the $0^+$ states of the nucleus $^{44}$Ti. The Gamow Shell Model is used to calculate the structure part of the alpha-decay, while the Gamow wave function determines the reaction part. The conventional and normalized spectroscopic factors are calculated for the ground and excited $0^+$ states of $^{44}$Ti and the alpha-width and half-life of the excited states. A near alpha-threshold state has an alpha half-life of 5 $μ$sec. The normalization does not appreciably modify the ground-state clusterization, while the excited states do. The non-resonant continuum significantly increases the clustering of some of the excited states, particularly the $T=2$ state. The normalized formation amplitude looks like a single-particle wave function.
description: 8 pages, 7 figures, 44 references
Additional file 1 of Likely uptake of a future lung cancer screening programme in Hodgkin lymphoma survivors: a questionnaire study
Creators: name: Broadbent, Rachel
name: Armitage, Christopher J.
name: Crosbie, Philip
name: Radford, John
name: Linton, Kim
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1. Study questionnaire.
Wave Field Synthesis in a listening room
Creators: name: Erbes, Vera Dorothee
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 621.3 Electrical Engineering, Electronics

description: This thesis investigates the influence of the listening room on sound fields synthesised by Wave Field Synthesis. Methods are developed that allow for investigation of the spatial and timbral perception of Wave Field Synthesis in a reverberant environment using listening experiments based on simulation by binaural synthesis and room acoustical simulation. The results can serve as guidelines for the design of listening rooms for Wave Field Synthesis.
HAMSTER: Hyperspectral Albedo Maps dataset with high Spatial and TEmporal Resolution
Creators: name: Roccetti, Giulia
name: Bugliaro, Luca
name: Gödde, Felix
name: Emde, Claudia
name: Hamann, Ulrich
name: Manev, Mihail
name: Sterzik, Michael
name: Wehrum, Cedric
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences
subject: 86A10

description: Surface albedo is an important parameter in radiative transfer simulations of the Earth's system, as it is fundamental to correctly calculate the energy budget of the planet. The Moderate Resolution Imaging Spectroradiometer (MODIS) instruments on NASA's Terra and Aqua satellites continuously monitor daily and yearly changes in reflection at the planetary surface. The MODIS Surface Reflectance black-sky albedo dataset (MCD43D, version 6.1) gives detailed albedo maps in seven spectral bands in the visible and near-infrared range. These albedo maps allow us to classify different Lambertian surface types and their seasonal and yearly variability and change, albeit only in seven spectral bands. However, a complete set of albedo maps covering the entire wavelength range is required to simulate radiance spectra, and to correctly retrieve atmospheric and cloud properties from Earth's remote sensing. We use a Principal Component Analysis (PCA) regression algorithm to generate hyperspectral albedo maps of Earth. Combining different datasets of hyperspectral reflectance laboratory measurements for various dry soils, vegetation surfaces, and mixtures of both, we reconstruct the albedo maps in the entire wavelength range from 400 to 2500~nm. The PCA method is trained with a 10-years average of MODIS data for each day of the year. We obtain hyperspectral albedo maps with a spatial resolution of 0.05° in latitude and longitude, a spectral resolution of 10~nm, and a temporal resolution of 1~day. Using the hyperspectral albedo maps, we estimate the spectral profiles of different land surfaces, such as forests, deserts, cities and icy surfaces, and study their seasonal variability. These albedo maps shall enable to refine calculations of Earth's energy budget, its seasonal variability, and improve climate simulations.
description: 32 pages, 19 figures. Accepted for publication on Atmospheric Measurement Techniques (AMT, Copernicus)
Superheroes social skills: an initial study examining an evidence-based program for elementary-aged students with autism spectrum disorders in a school setting
Creators: name: Block, Heidi Marie
Publisher: name: University of Utah
Year: 2012
Subjects: Autism spectrum disorders
Generalization
Peer-mediated
Self-management
Social skills
Video-modeling

description: The current study evaluated the effectiveness of a multimedia social skills program in increasing the social engagement skills of 4 elementary-aged students with an autism spectrum disorder. The Superheroes Social Skills for Children with Autism program incorporates several evidence-based practices into one comprehensive curriculum, namely video-modeling, peer-mediated instruction, self-management strategies, and usage of social narratives. Generalization strategies are also embedded in the program. Typically developing peers, serving as "peer buddies," were nominated by their classroom teachers and participated in the social skills training. The intervention was implemented for 11 weeks with training occurring for 30 minutes twice per week in a public elementary school. Effects were primarily assessed through 10-minute filmed observations taken during both analog free play and recess sessions for baseline, intervention, and follow-up phases. During these observations, each participant's percentage of time spent socially engaging, including both social initiations and responses, was coded using an adapted version of the Bellini (2007) social observation system. Both effect sizes and the percentage of nonoverlapping data points (PND) were calculated. Pre- and posttreatment effects were evaluated for the Social Responsiveness Scale (SRS) and the Autism Social Skills Profile (ASSP). Consumer satisfaction, social validity, and treatment integrity factors were also examined.
Effect of motor imagery on the neurological activation of the immobilized soleus muscle
Creators: name: Bengel, Stefanie
Publisher: name: University of Utah
Year: 2012
Subjects: Ankle injuries
Imagery

description: Injuries to the lower leg occur often in the physically active population and  immobilization of a short time is used as part of the treatment protocol. However,  immobilization has been found to alter the neurological system of the lower extremity.  This study seeks to investigate whether the use of motor imagery can attenuate any  detrimental effects of immobilization.  Participants were healthy with a moderate physical activity level as well as  moderate imagery ability. Fifteen individuals were divided into two groups: an imagery (4  males, 3 females) and control group (6 males, 2 females). All participants were  immobilized in a walking boot for 5 days and the H-reflex was measured. The imagery  group underwent imagery training three times a day whereas the control group received no  intervention.  A 2 x 3 RM-ANOVA was used to investigate the effect of motor imagery on  motoneuron pool excitability during immobilization. The H-reflex was the dependent  variable and time (baseline, day 3 and day 5) and group (imagery, control) the  independent variables with significance set at 0.05.  No significant interaction was found, suggesting no change in motoneuron pool  excitability with the use of imagery compared to the control group. Therefore, the use of  imagery had no influence on the neurological activity of the lower leg as measured by the  H-Reflex in this study. The absence of a time effect indicated that immobilization did not have the expected effect on the H-reflex. Participant responses were highly variable and  several measurement issues may have affected the results. A majority of the imagery were  able to stabilize their H-reflex with imagery over 5 days.  The results of this study enhance understanding of the neurological mechanisms  and changes occurring during immobilization and the role motor imagery plays.  Furthermore, this study serves as a base to build upon for future research.
Additional file 1 of Likely uptake of a future a lung cancer screening programme in Hodgkin lymphoma survivors: a questionnaire study
Creators: name: Broadbent, Rachel
name: Armitage, Christopher J.
name: Crosbie, Philip
name: Radford, John
name: Linton, Kim
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1. Study questionnaire.
Design and simulation of a control system for a hybrid lift assist device
Creators: name: Patel, Dhaval D.
Publisher: name: University of Utah
Year: 2012

description: Manual Material Handing (MMH) is a common activity for many workers in the workplace. Back compressive force has been described as a leading factor causing back injuries and musculoskeletal disorders (MSD) associated with lifting. To prevent such injuries, mechanical Lift Assist Devices (LAD) have been developed. To improve device usability and allow more interaction with human body movements, a significant step has been taken towards developing an automatic feedback control system for a hybrid lift assist device. The control system is highly responsive which would likely result in a reduction of required erector spine muscle force during lifting tasks. The control system is based on multiple input and multiple output (MIMO).This design was chosen to control the outputs of Torque (τ) and Speed (ω) generated from a DC motor from the inputs: hip angle, torso angle and HD (Horizontal Distance from L5/S1 to center of load derived from the Force and Center of Pressure (COP) using Flexi Force Sensors in the shoe insole). All the inputs were derived and compared with parameters of human body movement recorded using Vicon Nexus and 8 Bonita cameras. The Utah Back Compressive model was used to estimate the desired torque required by the LAD. The motor is controlled to generate the amount of torque to lift the load and to assist the body to a specified percent assist (0-100%). The design of the control system was achieved using a proper controller and DC motor with a closed loop feedback system. The control system produces reliable and robust performance for a variety of sagittal plane lifting techniques. This was accomplished by deriving the system input parameters from measurable device features and fine tuning the controller and selected DC motor model. These results indicate that a hybrid lifting assist device is feasible and can be programmed to provide variable assistance during lifting tasks.
Solution Structure of a Benzimidazole Inhibitor in Complex with Domain IIA of the Hepatitis C Virus Internal Ribosome Entry Site
Creators: name: Paulsen, Ryan B.
Publisher: name: University of Utah
Year: 2014

description: The solution structure of domain IIa of the hepatitis C virus internal ribosome entry site in complex with a racemic benzimidazole inhibitor was determined by NMR spectroscopy with corroborating fluorescence data. A 38 base RNA construct representing the inhibitor-binding region of domain IIa was synthesized by T7 RNA polymerase. Fully and selectively 13C and 15N labeled and isotopically unlabeled RNA samples were produced and studied in complex with the inhibitor. The inhibitor was previously shown to have inhibitory activity in an HCV replicon assay. It was also previously found to bind in the bulge region of domain IIa. In the free RNA, this five base bulge region introduces a bend in the extended domain II that situates the terminus of the domain over the mRNA cleft in the ribosomal E site. This hinge-like bulge region is not a known binding site for any host or viral translational cofactors, but domain II has been shown to be critical for IRES function, and the bulgeinduced bend in domain IIa has been shown to be important for IRES function in mutagenesis assays. Molecular dynamics refinement in explicit solvent and subsequent free energetic analysis indicate that the inhibitor enantiomers bind with comparable affinity and equivalent binding modes. The structure of this inhibitor/RNA complex suggests that the small molecule rearranges the base stacking in the bulge and introduces a significant conformational change that eliminates the bent RNA helical trajectory. This suggests a iv possible mechanism of inhibition involving the displacement of the domain II terminus from the mRNA cleft on the ribosomal E site. Perhaps most importantly, this structure may serve as a guide in the development of second-generation higher affinity inhibitors of the hepatitis C IRES as well as provide general insights into small molecule inhibitor interactions with RNA.
Additional file 10 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 10. Table S4. Differentially expressed genes (DEGs) from comparing Dengue Hemorrhagic Fever (DHF) with Dengue Fever (DF) in EA group. (EA, Early Acute stage).
Additional file 11 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 11. Table S5. Differentially expressed genes (DEGs) from comparing Dengue Hemorrhagic Fever (DHF) with Dengue Fever (DF) in LA group. (LA, Late Acute stage).
Additional file 1 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1. Figure S1. (A–C) PCA shows that different stages can be distinguished. Weighted co-expression network analysis (WGCNA). (D–F) Showing the cutoff height. (G–I) Sample clustering. (J) Shared gene (CCL2) in the LA stage between DEGs (between Dengue Hemorrhagic Fever (DHF) and Dengue Fever (DF)) and 232 autophagy-related genes, and (K) its expression levels. Similar expression levels of CD38 and CDKN1C between DH and DHF (L) and among different serotypes (M). S1, serotype I; S2, serotype II; S3, serotype III; S4, serotype IV. (C, Convalescent stage; EA, Early Acute stage; LA, Late Acute stage).
A study of bladder impedance measurements and cystometry.
Creators: name: Burkinshaw, Brenda Boyd
Publisher: name: University of Utah
Year: 2012
Subjects: Bladder
Exmination
Cytometry

description: Tetrapolar impedance is a non-invasive method of measuring urine volume in the bladder. Changes in the urine volume can be measured by alterations in the impedance measurements.  Impedance measurements are obtained by using a tetrapolar impedance converter with four electrodes placed on the subject's abdomen.  Measuring impedance changes occurs while the bladder fills with urine.  An assessment of urine volume and bladder function is essential to determine an index of renal function and urinary stasis in postsurgical patients, paraplegics and those patients with neurogenic bladder dysfunction.  The purpose of this investigation was to describe a noninvasive method, tetrapolar impedance, by measuring urine volume and residual.  The impedance measurements were obtained on three subjects during cystometry studies.  The changes in impedance were compared with the simultaneous changes in bladder fluid volume as the cystometric fluid was instilled.  Few clinically and statistically significant results were obtained from the small number of subjects in this investigation.  The first two case studies did not show a significant comparison for impedance changes.  They did, however, help to verify that there is some relationship between the change in cystometric capacity and cystometric pressure readings.  The information obtained from these case studies can be used to help compare impedance measurements with those of cystometry in the future.  However, the third can case did show promise of substantial comparison between impedance measurements and cystometry.
Additional file 2 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 2. Figure S2. Analyzing staging diagnosis value of CD38 and CDKN1C for four serotypes among three comparison groups by Area Under the Curve (AUC) in the training set (GSE43777 dataset of GLP201 platform), respectively. (A) C vs EA in serotype I; (B) C vs LA in serotype I; (C) EA vs LA in serotype I; (D) C vs EA in serotype II; (E) C vs LA in serotype II; (F) EA vs LA in serotype II; (G) C vs EA in serotype III; (H) C vs LA in serotype III; (I) EA vs LA in serotype III; (J) C vs EA in serotype IV; (K) C vs LA in serotype IV; (L) EA vs LA in serotype IV. (C, Convalescent stages; EA, Early Acute stage; LA, Late Acute stage).
Additional file 3 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 3. Figure S3. Analyzing staging diagnosis value of CD38 and CDKN1C for four serotypes among three comparison groups by Area Under the Curve (AUC) in the test set (GSE43777 dataset of GLP570 platform), respectively. (A) C vs EA in serotype I; (B) C vs LA in serotype I; (C) EA vs LA in serotype I; (D) C vs EA in serotype II; (E) C vs LA in serotype II; (F) EA vs LA in serotype II; (G) C vs EA in serotype III; (H) C vs LA in serotype III; (I) EA vs LA in serotype III; (J) C vs EA in serotype IV; (K) C vs LA in serotype IV; (L) EA vs LA in serotype IV. (C, Convalescent stage; EA, Early Acute stage; LA, Late Acute stage).
Additional file 5 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 5. Figure S5. Correlation between CD38 and 22 types of immune cells (red rectangular: statistically significant (P < 0.05)). (A) In serotype I; (B) in serotype II; (C) in serotype III; (D) in serotype IV. (C, Convalescent stage; EA, Early Acute stage; LA, Late Acute stage).
American colonial policy in the Philippines (1916-1932)
Creators: name: Limbos, Tomas Zamora
Publisher: name: University of Utah
Year: 2015
Subjects: Philippines
American colonial policy
Jones act

description: The United States' colonial policy in the Philippines as first enunciated by President McKinley contemplated the preparation of the islanders for a speedy participation in the government with the ultimate object of granting them independence under a democracy in the form of a republic.
Additional file 4 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 4. Figure S4. Violin diagrams and heatmaps display immune differences of immune cells in different comparing groups. (A) C vs EA stages in the serotype I. (B) C vs LA stages in the serotype I. (C) EA vs LA stages in the serotype I. (D) Immune difference heatmap of the serotype I in three stages. (E) C vs EA stages in the serotype II. (F) C vs LA stages in the serotype II. (G) EA vs LA stages in the serotype II. (H) Immune difference heatmap of the serotype II in three stages. (I) C vs EA stages in the serotype III. (J) C vs LA stages in the serotype III. (K) EA vs LA stages in the serotype III. (L) Immune difference heatmap of the serotype III in three stages. (M) C vs EA stages in the serotype IV. (N) C vs LA stages in the serotype IV. (O) EA vs LA stages in the serotype IV. (P) Immune difference heatmap of the serotype IV in three stages. (C, Convalescent stage; EA, Early Acute stage; LA, Late Acute stage).
Additional file 6 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 6. Figure S6. Analyzing staging diagnosis value of immune cells for Dengue by Area Under the Curve (AUC) in each serotype. (A) C vs EA stages in the serotype I. (B) C vs LA stages in the serotype I. (C) EA vs LA stages in the serotype I. (D) C vs EA stages in the serotype II. (E) C vs LA stages in the serotype II. (F) EA vs LA stages in the serotype II. (G) C vs EA stages in the serotype III. (H) C vs LA stages in the serotype III. (I) EA vs LA stages in the serotype III. (J) C vs EA stages in the serotype IV. (K) C vs LA stages in the serotype IV. (L) EA vs LA stages in the serotype IV. (C, Convalescent stage; EA, Early Acute stage; LA, Late Acute stage).
Additional file 7 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 7. Table S1. Differentially expressed genes (DEGs) in the C vs EA group. (C, Convalescent stage; EA, Early Acute stage).
Additional file 8 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 8. Table S2. Differentially expressed genes (DEGs) in the C vs LA group. (C, Convalescent stage; LA, Late Acute stage).
CO2 displacement mechanisms: phase equilibria effects and carbon dioxide sequestration studies
Creators: name: Pasala, Sangeetha M.
Publisher: name: University of Utah
Year: 2012
Subjects: CO2 displacement
Carbon dioxide sequestration
Enhanced oil recovery

description: Supercritical carbon dioxide is injected into underground formations to enhance oil recovery and for subsurface sequestration to minimize the impact of CO2 emissions due to global warming. The complex phase behavior of CO2 with oil determines the effectiveness of the CO2 injection for enhanced oil recovery. The injection of CO2 into the subsurface is also affected by the large and small scale heterogeneities in the formations. These two aspects of CO2 injection are examined in this research.  Development of multiple-contact miscibility is important in the success of a carbon dioxide enhanced oil recovery. CO2 displacements are often designed to  operate above the minimum miscibility pressure (MMP) to ensure the development of multiple contact miscibility between the oil and CO2. Compositional histories in  different parts of a two-dimensional domain are examined in this study in relation to displacement pressure employed. The second part of this dissertation deals with the effect of faults on the CO2 sequestration process and on the integrity of storage. Outcrop-based studies of faulted, aeolian Navajo sandstone provide detailed, quantitative insight regarding the range of fault characteristics that might be encountered as injected CO2 migrates through the faulted aquifer. Faults can act as barriers, conduits, or integrated barrier-conduit systems. Uncertainty in knowing whether a subsurface fault will act as a barrier or conduit leads to uncertainty in evaluating the likelihood for economically sequestering CO2 in sandstone aquifers. EclipseR  black oil reservoir simulator is used to explore how different, 3-D, fault-related permeability/porosity structures might impact CO2 injection into, migration through, and leakage from a sequestration aquifer. Sandstone permeability values range from 10s to 1000s of mD. Simulator output shows how fault conduits and barriers can restrict migration of CO2 through the aquifer as a consequence of bypassing (conduits) or compartmentalization (barriers). In addition, the simulation results reveal how the geoscientists' ability to quantify and discriminate between high-permeability versus low-permeability faults in sandstone aquifers can play an important role in designing CO2 sequestration operations.
Difficulty Estimation and Simplification of French Text Using LLMs
Creators: name: Jamet, Henri
name: Shrestha, Yash Raj
name: Vlachos, Michalis
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: We leverage generative large language models for language learning applications, focusing on estimating the difficulty of foreign language texts and simplifying them to lower difficulty levels. We frame both tasks as prediction problems and develop a difficulty classification model using labeled examples, transfer learning, and large language models, demonstrating superior accuracy compared to previous approaches. For simplification, we evaluate the trade-off between simplification quality and meaning preservation, comparing zero-shot and fine-tuned performances of large language models. We show that meaningful text simplifications can be obtained with limited fine-tuning. Our experiments are conducted on French texts, but our methods are language-agnostic and directly applicable to other foreign languages.
description: 10 pages, 4 figures
Diversification of Hox gene function as a consequence of evolution in cis-regulator sequences.
Creators: name: Greer, Joy Marie
Publisher: name: University of Utah
Year: 2012
Subjects: Gene Evolution
Mutation

description: Hox genes are recognized for their universal role in patterning the antero-posterior (A-P) axis of metazoan embryos. Hox gene expression along the A-P axis occurs in a colinear fashion that reflects the chromosomal position of each gene, suggesting an evolutionary conservation for the function of Hox genes. In vertebrates, 39 Hox genes, distributed in four linkage groups on four chromosomes have been identified. Genes within the individual linkage groups are categorized based on similarities in sequence and expression pattern and are known as paralogs. The work contained in this dissertation demonstrates that evolutionary changes in the cis-regulatory sequences are responsible for the different functions of the murine paralogs Hoxa3 and Hoxd3. The proteins encoded by these two loci can perform equivalent functions during murine development, suggesting an evolutionary selection of functional equivalence. These findings support previous analyses suggesting a quantitative interaction between these proteins during murine development. Finally, analysis of animals lacking function of  Hoxb8 has revealed a behavioral phenotype characterized by excessive autogrooming. Grooming behaviors are represented in nearly every animal species, suggesting that it is an evolutionarily ancient behavior. Examination of Hoxb8 mutants did not reveal any morphological abnormalities. Rather, a novel expression pattern for Hoxb8 in the developing and adult central nervous system (CNS) is described. This expression pattern localizes to neuroanatomical structures that have previously been shown to regulate grooming behaviors in rodents. These studies suggest that Hoxb8 has evolved a function beyond embryogenesis.
Additional file 9 of Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses
Creators: name: Xiong, Nan
name: Sun, Qiangming
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 9. Table S3. Differentially expressed genes (DEGs) in the EA vs LA group. (EA, Early Acute stage; LA, Late Acute stage).
European recommendations on responsible research assessment
Creators: name: Pölönen, Janne
name: Mustajoki, Henriikka
Publisher: name: Zenodo
Year: 2022
Subjects: Research assessment
Open science
Science policy

description: Responsible research assessment entails recognizing diversity of research outputs, activities, missions, and difference between fields, as well as rewarding open science practices. Slow uptake of responsible assessment policies at institutions is partly due to lack of qualitative and quantitative data needed to document the broader range of merits for assessments. In recent years, implementation of responsible research assessment has been promoted by national recommendations in three European countries (the Netherlands 2019, Finland 2020, and Norway 2021). Most recently, the European Commission aims to facilitate and speed up changes with a European agreement on a reform of the research assessment system. We analyze and compare the European Commision and three national documents on responsible assessment to show overlaps and differences in construction of policies, as well as continuities and discontinuities with earlier recommendations in DORA (2012), the Leiden manifesto (2015), and the Metric tide (2015). References: Curry, S., de Rijcke, S., Hatch, A., Pillay, D.; van der Weijden, I. & Wilsdon, J. (2020). The changing role of funders in responsible research assessment: progress, obstacles and the way ahead. European Commission (2021). Towards a reform of the research assessment system. Federation of Finnish Learned Societies (2020). Good practice in researcher evaluation. Recommendation for the responsible evaluation of a researcher in Finland. Mustajoki, H., Pölönen, J., Gregory, K., Ivanović, D., Brasse, V., Kesäniemi, J., Koivisto, E., & Pylvänäinen, E. (2021). Making FAIReR assessments possible. Final report of EOSC Co-Creation projects: "European overview of career merit systems'' and "Vision for research data in research careers". Universities Norway (2021). NOR-CAM - A toolbox for recognition and rewards in academic careers. VSNU, NFU, KNAW, NWO and ZonMw (2019). Room for everyone’s talent: towards a new balance in the recognition and rewards of academics.
Development of microplate immunoassay methods for the measurement of prostate specific antigen and its [alpha1antichymotrypsin complex in serum.
Creators: name: Wilson, Lorraine Welch
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Diagnosis

description: The measurement of prostate specific antigen (PSA) is used as both a screening test for prostate cancer and for monitoring treatment of the disease.  Although several methods have been developed to measure PSA, the results produced are not equivalent for all samples and assay methods.  These problems are caused by differences in antibody affinity for the different forms of PSA present in serum and difference in the composition of the calibrator used for each assay.  Methods for quantification of PSA that are not affected by these problems were developed.  Two assays were developed, a total PSA assay and an assay specific for PSA complexed of alpha1-anatichymotrypsin (PSA-ACT).  The antibodies selected for the assays demonstrate similar affinity for both forms of PSA.  Pooled sera containing approximately 95% PSA-ACT complex and 5% free PSA was used as a calibrator in order to closely match the immuno-reactivity and PSA composition of serum samples.  The test format selected for total PSA assay uses polyclonal anti- PSA antibodies coated on the solid phase and monoclonal anti- PSA antibodies for quantification.  Two different sample volumes, 5 and 50 micro liters each were used for the assay.  The total PSA assay has a reportable range from zero to 500 ng/mL.  The sensitivity is 0.06 ng/mL.  The within day precision is 5% calculated as the percent coefficient of variation for samples between 4 and 12 ng/mL.  The run to run precision is less than 10%.  No hook effect was seen in either assay for samples with concentrations up to 15,000 ng/mL.  The total PSA results correlate well with the Hybritech Tandem  E. PSA kit producing a correlation coefficient of 0.996 and a slope of 0.927.  These results demonstrate that the total PSA assay is satisfactory for use in the clinical laboratory.  The PSA-ACT specific assay also correlates will with the Hybritech E PSA and is a possible replacement for the total PSA assay.
Sonnenfleckenzeichnung Nr. 21733.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 13.08.1964, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1964

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt