cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 2: of Impact of patient involvement on clinical practice guideline development: a parallel group study
Creators: name: Armstrong, Melissa
name: C. Mullins
name: Gronseth, Gary
name: Gagliardi, Anna
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Developmental Biology
Cancer
Science Policy
Computational Biology

description: COREQ 32-item checklist for manuscript â Impact of Patient Involvement on Clinical Practice Guideline Question Formation: A Randomized Controlled Studyâ . COREQ checklist. (DOCX 16 kb)
On the Determination of N and O Abundances in Low Metallicity Systems
Creators: name: Nava, A.
name: Casebeer, D.
name: Henry, R. B. C.
name: Jevremovic, D.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We show that in order to minimize the uncertainties in the N and O abundances of low mass, low metallicity (O/H less than or equal to solar/5) emission-line galaxies, it is necessary to employ separate parameterizations for inferring Te[N II] and Te[O II] from Te[O III]. In addition, we show that for the above systems, the ionization correction factor (ICF) for obtaining N/O from N+/O+, where the latter is derived from optical emission-line flux ratios, is < ICF > = 1.08 +/- 0.09. These findings are based on state-of-the-art single-star H II region simulations, employing our own modeled stellar spectra as input. Our models offer the advantage of having matching stellar and nebular abundances. In addition, they have O/H as low as solar/50 (lower than any past work), as well as log(N/O) and log(C/O) fixed at characteristic values of -1.46 and -0.7, respectively. The above results were used to re-derive N and O abundances for a sample of 68 systems with 12 + log(O/H) less than or equal to 8.1, whose de-reddened emission-line strengths were collected from the literature. The analysis of the log(N/O) versus 12 + log(O/H) diagram of the above systems shows the following: (1) the largest group of objects forms the well-known N/O plateau with a value for the mean (and its statistical error) of -1.43 (+.0084/-.0085); (2) the objects are distributed within a range in log(N/O) of -1.54 to -1.27 in Gaussian fashion around the mean with a standard deviation of sigma = +.071 / -.084; and (3) a chi-square analysis suggests that only a small amount of the observed scatter in log(N/O) is intrinsic.
description: 15 pages, 13 figures, 6 tables, accepted for publication in ApJ
Increasing the proportion of healthier foods available with and without reducing portion sizes and energy purchased in worksite cafeterias: protocol for a stepped-wedge randomised controlled trial.
Creators: name: Reynolds, James P
name: Kosīte, Daina
name: Rigby Dames, Brier
name: Brocklebank, Laura A
name: Pilling, Mark
name: Pechey, Rachel
name: Hollands, Gareth J
name: Marteau, Theresa M
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Obesity
Availability
Randomised Controlled Trial
Choice Architecture
Portion Size
Workplace Interventions
Stepped Wedge Trial
Healthier Eating
Physical Micro-environment Interventions
Nudging

description: BACKGROUND:Overconsumption of energy from food contributes to high rates of overweight and obesity in many populations. A promising set of interventions tested in pilot studies in worksite cafeterias, suggests energy intake may be reduced by increasing the proportion of healthier - i.e. lower energy - food options available, and decreasing portion sizes. The current study aims to assess the impact on energy purchased of i. increasing the proportion of lower energy options available; ii. combining this with reducing portion sizes, in a full trial. METHODS:A stepped-wedge randomised controlled trial in 19 worksite cafeterias, where the proportion of lower energy options available in targeted food categories (including main meals, snacks, and cold drinks) will be increased; and combined with reduced portion sizes. The primary outcome is total energy (kcal) purchased from targeted food categories using a pooled estimate across all sites. Follow-up analyses will test whether the impact on energy purchased varies according to the extent of intervention implementation. DISCUSSION:This study will provide the most reliable estimate to date of the effect sizes of two promising interventions for reducing energy purchased in worksite cafeterias. TRIAL REGISTRATION:The study was prospectively registered on ISRCTN (date: 24.05.19; TRN: ISRCTN87225572; doi: https://doi.org/10.1186/ISRCTN87225572).
On the simplest scale invariant Tree-Tensor-States preserving the quantum symmetries of the antiferromagnetic XXZ chain
Creators: name: Monthus, Cecile
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: For the line of critical antiferromagnetic XXZ chains with coupling $J>0$ and anisotropy $0
description: v2=final version (17 pages)
Sample size re-estimation in crossover trials: application to the AIM HY-INFORM study.
Creators: name: Wych, Julie
name: Grayling, Michael J
name: Mander, Adrian P
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Hypertension
Sample Size Calculation
Simulation Study
Crossover Trial
Aim Hy-inform Study

description: BACKGROUND:Crossover designs are commonly utilised in randomised controlled trials investigating treatments for long-term chronic illnesses. One problem with this design is its inherent repeated measures necessitate the availability of an estimate of the within-person standard deviation (SD) to perform a sample size calculation, which may be rarely available at the design stage of a trial. Interim sample size re-estimation designs can be used to help alleviate this issue by adapting the sample size mid-way through the trial, using accrued information in a statistically robust way. METHODS:The AIM HY-INFORM study is part of the Informative Markers in Hypertension (AIM HY) Programme and comprises two crossover trials, each with a planned recruitment of 600 participants. The objective of the study is to test whether blood pressure response to first line antihypertensive treatment depends on ethnicity. An interim analysis is planned to reassess the assumptions of the planned sample size for the study. The aims of this paper are: (1) to provide a formula for sample size re-estimation in both crossover trials; and (2) to present a simulation study of the planned interim analysis to investigate alternative within-person SDs to that assumed. RESULTS:The AIM HY-INFORM protocol sample size calculation fixes the within-person SD to be 8 mmHg, giving > 90% power for a primary treatment effect of 4 mmHg. Using the method developed here and simulating the interim sample size reassessment, if we were to see a larger within-person SD of 9 mmHg at interim, 640 participants for 90% power 90% of the time in the three-period three-treatment design would be required. Similarly, in the four-period four-treatment crossover design, 602 participants would be required. CONCLUSIONS:The formulas presented here provide a method for re-estimating the sample size in crossover trials. In the context of the AIM HY-INFORM study, simulating the interim analysis allows us to explore the results of a possible increase in the within-person SD from that assumed. Simulations show that without increasing the planned sample size of 600 participants, we can reasonably still expect to achieve 80% power with a small increase in the within-person SD from that assumed. TRIAL REGISTRATION:ClinicalTrials.gov, NCT02847338. Registered on 28 July 2016.
title: ADCO, Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Cart. 31 (G 135), 549 folios, f. 0650
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0650, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Huitième cartulaire de Saint-Étienne de Dijon (1661-1667), Archives départementales de la Côte-d'Or, Cart. 31 (G 135), 549 folios, f. 0650, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Chromosome-scale assembly comparison of the Korean Reference Genome KOREF from PromethION and PacBio with Hi-C mapping information.
Creators: name: Kim, Hui-Su
name: Jeon, Sungwon
name: Kim, Changjae
name: Kim, Yeon Kyung
name: Cho, Yun Sung
name: Kim, Jungeun
name: Blazyte, Asta
name: Manica, Andrea
name: Lee, Semin
name: Bhak, Jong
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Hi-c
Single-molecule Sequencing
Nanopore Sequencing
Koref
Korean Reference Genome
Promethion

description: BACKGROUND:Long DNA reads produced by single-molecule and pore-based sequencers are more suitable for assembly and structural variation discovery than short-read DNA fragments. For de novo assembly, Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) are the favorite options. However, PacBio's SMRT sequencing is expensive for a full human genome assembly and costs more than $40,000 US for 30× coverage as of 2019. ONT PromethION sequencing, on the other hand, is 1/12 the price of PacBio for the same coverage. This study aimed to compare the cost-effectiveness of ONT PromethION and PacBio's SMRT sequencing in relation to the quality. FINDINGS:We performed whole-genome de novo assemblies and comparison to construct an improved version of KOREF, the Korean reference genome, using sequencing data produced by PromethION and PacBio. With PromethION, an assembly using sequenced reads with 64× coverage (193 Gb, 3 flowcell sequencing) resulted in 3,725 contigs with N50s of 16.7 Mb and a total genome length of 2.8 Gb. It was comparable to a KOREF assembly constructed using PacBio at 62× coverage (188 Gb, 2,695 contigs, and N50s of 17.9 Mb). When we applied Hi-C-derived long-range mapping data, an even higher quality assembly for the 64× coverage was achieved, resulting in 3,179 scaffolds with an N50 of 56.4 Mb. CONCLUSION:The pore-based PromethION approach provided a high-quality chromosome-scale human genome assembly at a low cost with long maximum contig and scaffold lengths and was more cost-effective than PacBio at comparable quality measurements.
Additional file 2: of Genome analysis of the freshwater planktonic Vulcanococcus limneticus sp. nov. reveals horizontal transfer of nitrogenase operon and alternative pathways of nitrogen utilization
Creators: name: Cesare, Andrea Di
name: Cabello-Yeves, Pedro
name: Chrismas, Nathan
name: SĂĄnchez-Baracaldo, Patricia
name: Salcher, Michaela
name: Callieri, Cristiana
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Fig. S2. Growth experiment of V.limneticus sp. nov. kept in two culture conditions: with and without nitrogen in the culture medium. The dark periods are reported as grey area. The number of cells are reported as mean of 3 replicates Âą standard deviation. (PDF 337Â kb)
The ESO Diffuse Interstellar Bands Large Exploration Survey: EDIBLES I. Project description, survey sample and quality assessment
Creators: name: Cox, Nick
name: Cami, Jan
name: Farhang, Amin
name: Smoker, Jonathan
name: Monreal-Ibero, Ana
name: Lallement, Rosine
name: Sarre, Peter
name: Marshall, Charlotte
name: Smith, Keith
name: Evans, Christopher
name: Royer, Pierre
name: Linnartz, Harold
name: Cordiner, Martin
name: Joblin, Christine
name: van Loon, Jacco
name: Foing, Bernard
name: Bhatt, Neil
name: Bron, Emeric
name: Elyajouri, Meriem
name: de Koter, Alex
name: Ehrenfreund, Pascale
name: Javadi, Atefeh
name: Kaper, Lex
name: Khosroshadi, Habib
name: Laverick, Mike
name: Petit, Franck Le
name: Mulas, Giacomo
name: Roueff, Evelyne
name: Salama, Farid
name: Spaans, Marco
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The carriers of the diffuse interstellar bands (DIBs) are largely unidentified molecules ubiquitously present in the interstellar medium (ISM). After decades of study, two strong and possibly three weak near-infrared DIBs have recently been attributed to the C60+ fullerene based on observational and laboratory measurements. There is great promise for the identification of the over 400 other known DIBs, as this result could provide chemical hints towards other possible carriers. In an effort to systematically study the properties of the DIB carriers, we have initiated a new large-scale observational survey: the ESO Diffuse Interstellar Bands Large Exploration Survey (EDIBLES). The main objective is to build on and extend existing DIB surveys to make a major step forward in characterising the physical and chemical conditions for a statistically significant sample of interstellar lines-of-sight, with the goal to reverse-engineer key molecular properties of the DIB carriers. EDIBLES is a filler Large Programme using the Ultraviolet and Visual Echelle Spectrograph at the Very Large Telescope at Paranal, Chile. It is designed to provide an observationally unbiased view of the presence and behaviour of the DIBs towards early-spectral-type stars whose lines-of-sight probe the diffuse-to-translucent ISM. Such a complete dataset will provide a deep census of the atomic and molecular content, physical conditions, chemical abundances and elemental depletion levels for each sightline. Achieving these goals requires a homogeneous set of high-quality data in terms of resolution (R ~ 70000 -- 100000), sensitivity (S/N up to 1000 per resolution element), and spectral coverage (305--1042 nm), as well as a large sample size (100+ sightlines). In this first paper the goals, objectives and methodology of the EDIBLES programme are described and an initial assessment of the data is provided.
description: 29 pages (including 14 pages appendix), 15 figures, accepted by A&A
Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure.
Creators: name: Ward, Joey
name: Lyall, Laura M
name: Bethlehem, Richard A I
name: Ferguson, Amy
name: Strawbridge, Rona J
name: Lyall, Donald M
name: Cullen, Breda
name: Graham, Nicholas
name: Johnston, Keira J A
name: Bailey, Mark E S
name: Murray, Graham K
name: Smith, Daniel J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019

description: Anhedonia is a core symptom of several psychiatric disorders but its biological underpinnings are poorly understood. We performed a genome-wide association study of state anhedonia in 375,275 UK Biobank participants and assessed for genetic correlation between anhedonia and neuropsychiatric conditions (major depressive disorder, schizophrenia, bipolar disorder, obsessive compulsive disorder and Parkinson's Disease). We then used a polygenic risk score approach to test for association between genetic loading for anhedonia and both brain structure and brain function. This included: magnetic resonance imaging (MRI) assessments of total grey matter volume, white matter volume, cerebrospinal fluid volume, and 15 cortical/subcortical regions of interest; diffusion tensor imaging (DTI) measures of white matter tract integrity; and functional MRI activity during an emotion processing task. We identified 11 novel loci associated at genome-wide significance with anhedonia, with a SNP heritability estimate (h2SNP) of 5.6%. Strong positive genetic correlations were found between anhedonia and major depressive disorder, schizophrenia and bipolar disorder; but not with obsessive compulsive disorder or Parkinson's Disease. Polygenic risk for anhedonia was associated with poorer brain white matter integrity, smaller total grey matter volume, and smaller volumes of brain regions linked to reward and pleasure processing, including orbito-frontal cortex. In summary, the identification of novel anhedonia-associated loci substantially expands our current understanding of the biological basis of state anhedonia and genetic correlations with several psychiatric disorders confirm the utility of this phenotype as a transdiagnostic marker of vulnerability to mental illness. We also provide the first evidence that genetic risk for state anhedonia influences brain structure, including in regions associated with reward and pleasure processing.
Abelian dominance and adjoint sources in lattice QCD
Creators: name: Poulis, Grigorios I.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: Certain properties of maximal abelian projection are derived which suggest that the fundamental and adjoint SU(2) string tensions are reproduced by singly and doubly charged abelian Wilson loops, respectively. Thus, abelian dominance, which has been observed for color sources (quarks) in the fundamental representation, can be extended to higher representations. Numerical evidence in support of this conjecture also for adjoint quarks is presented. The difference between maximal abelian and local projections is elucidated and the role of non-Wilson-like terms in the effective abelian action is discussed.
description: 24 pages. Uuencoded gz-compressed tar file; includes RevTeX source plus 12 postscript figures incorporated via epsfig.sty. Complete postscript file available via WWW at http://www.nikhefk.nikhef.nl/projects/Theory/preprints/preprints.html
Additional file 1: of Relevance and acceptability of using the Quantiferon gold test (QGIT) to screen CD4 blood draws for latent TB infection among PLHIV in South Africa: formative qualitative research findings from the TEKO trial
Creators: name: Kerrigan, Deanna
name: Tudor, Carrie
name: Katlego Motlhaoleng
name: Limakatso Lebina
name: Cokiswa Qomfu
name: Variava, Ebrahim
name: Chon, Sandy
name: Martinson, Neil
name: Golub, Jonathan
Publisher: name: figshare
Year: 2018
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: In-depth interview guides for patients and care providers. (DOCX 32Â kb)
A metastable subproteome underlies inclusion formation in muscle proteinopathies.
Creators: name: Ciryam, Prajwal
name: Antalek, Matthew
name: Cid, Fernando
name: Tartaglia, Gian Gaetano
name: Dobson, Christopher M
name: Guettsches, Anne-Katrin
name: Eggers, Britta
name: Vorgerd, Matthias
name: Marcus, Katrin
name: Kley, Rudolf A
name: Morimoto, Richard I
name: Vendruscolo, Michele
name: Weihl, Conrad C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019

description: Protein aggregation is a pathological feature of neurodegenerative disorders. We previously demonstrated that protein inclusions in the brain are composed of supersaturated proteins, which are abundant and aggregation-prone, and form a metastable subproteome. It is not yet clear, however, whether this phenomenon is also associated with non-neuronal protein conformational disorders. To respond to this question, we analyzed proteomic datasets from biopsies of patients with genetic and acquired protein aggregate myopathy (PAM) by quantifying the changes in composition, concentration and aggregation propensity of proteins in the fibers containing inclusions and those surrounding them. We found that a metastable subproteome is present in skeletal muscle from healthy patients. The expression of this subproteome escalate as proteomic samples are taken more proximal to the pathologic inclusion, eventually exceeding its solubility limits and aggregating. While most supersaturated proteins decrease or maintain steady abundance across healthy fibers and inclusion-containing fibers, proteins within the metastable subproteome rise in abundance, suggesting that they escape regulation. Taken together, our results show in the context of a human conformational disorder that the supersaturation of a metastable subproteome underlies widespread aggregation and correlates with the histopathological state of the tissue.
Membracoidea Rafinesque 1815
Creators: name: Boulard, M.
Publisher: name: Zenodo
Year: 2002
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera

description: 3.3 Membracoidea   Les Membracoidea, dont la taxonomie et la nomenclature fondamentales ont été récemment révisées par Deitz & DIETRICH (1993), est une Superfamille nombreuse que la diversité conduit à répartir en quatre familles principales totalisant une bonne trentaine de sous-familles bien caractérisées. Les taxons les plus remarquables pour notre propos sont les Cicadellidae (avec, notamment, les Cicadellinae, les Hylicinae, les Hecalinae et les Ledrinae), les Melizoderidae. les Aetalionidae (comprenant les Aetalioninae et les Biturritiinae) et les Membracidae (incluant 12 sous-familles, dont les Membracinae, les Endoiastinae, les Centrotinae, les Oxyrhachinae, les Heteronotinae, les Darninae et les Smiliinae nous retiendront plus particulièrement, la plupart comprenant chacune diverses tribus).
description: Published as part of Boulard, M., 2002, Diversité des Auchénorhynques Cicadomorphes Formes, couleurs et comportements (Diversité structurelle ou taxonomique Diversité particulière aux Cicadidés), pp. 171-214 in Denisia 4 on page 178, DOI: 10.5281/zenodo.10550994
Two levels of topology in skyrmion lattice dynamics
Creators: name: Schick, Daniel
name: Weißenhofer, Markus
name: Rózsa, Levente
name: Rothörl, Jan
name: Virnau, Peter
name: Nowak, Ulrich
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: Diffusion
subject: Skyrmions
subject: Topological defects
subject: 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik

description: Skyrmions are localized, topological spin structures that can be described as quasiparticles. Skyrmions in thin films are an ideal model system to study Brownian motion and lattice formation in two dimensions. They follow an equation of motion, the Thiele equation, which includes a topology-dependent chiral term, linear in velocity, causing a skyrmion Hall effect and a drastic reduction of the diffusion coefficient for individual skyrmions, as compared to normal Brownian particles. Using Brownian dynamics simulations, we show that this topological suppression of the diffusion can be partially lifted in two-dimensional lattices of skyrmions. Counterintuitively, this causes enhanced diffusive properties with increasing particle density, similar to odd-diffusive Brownian particles. We show how the topological charge of the skyrmions influences the dynamics of topological lattice defects, which also affects the dynamics of the phase formation.
Subwavelength sound screening by coupling space-coiled Fabry-Perot resonators
Creators: name: Elayouch, A.
name: Addouche, M.
name: Farhat, M.
name: Khelif, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Applied Physics (physics.app-ph)
subject: FOS: Physical sciences

description: We explore broadband and omnidirectional low frequency sound screening based on locally resonant acoustic metamaterials. We show that the coupling of different resonant modes supported by Fabry-Perot cavities can efficiently generate asymmetric lineshapes in the transmission spectrum, leading to a broadband sound opacity. The Fabry-Perot cavities are space-coiled in order to shift the resonant modes under the diffraction edge, which guaranty the opacity band for all incident angles. Indeed, the deep subwavelength feature of the cavities leads to avoid diffraction that have been proved to be the main limitation of omnidirectional capabilities of locally resonant perforated plates. We experimentally reach an attenuation of few tens of dB at low frequency, with a metamaterial thickness fifteen times smaller than the wavelength (lambda / 15). The proposed design can be considered as a new building block for acoustic metasurfaces having a high level of manipulation of acoustic waves.
description: 7 pages, 8 figures
Two Party Non-Local Games
Creators: name: Chakrabarty, Indranil
name: Choudhury, B. S.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work we have introduced two party games with respective winning conditions. One cannot win these games deterministically in the classical world if they are not allowed to communicate at any stage of the game. Interestingly we find out that in quantum world, these winning conditions can be achieved if the players share an entangled state. We also introduced a game which is impossible to win if the players are not allowed to communicate in classical world (both probabilistically and deterministically), yet there exists a perfect quantum strategy by following which, one can attain the winning condition of the game.
description: Accepted in International Journal of Theoretical Physics
Rifapentine is an entry and replication inhibitor against yellow fever virus both in vitro and in vivo
Creators: name: Qian, Xijing
name: Wu, Bingan
name: Tang, Hailin
name: Luo, Zhenghan
name: Xu, Zhenghao
name: Ouyang, Songying
name: Li, Xiangliang
name: Xie, Jianfeng
name: Yi, Zhigang
name: Leng, Qibin
name: Liu, Yan
name: Qi, Zhongtian
name: Zhao, Ping
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Virology

description: Yellow fever virus (YFV) infection threatens large populations in South America and Africa. No specific anti-YFV drugs are available till now. Here, we report that rifapentine is a potent YFV inhibitor in various cell lines by high-throughput drugs library screening, acting at both cell entry and replication steps. Kinetic test and binding assay suggest that rifapentine interferes the viral attachment to the target cells. The application of YFV replicon and surface plasmon resonance assay indicates that rifapentine suppresses viral replication by binding to the RNA-dependent RNA polymerase (RdRp) domain of viral nonstructural protein NS5. Further molecular docking suggests that it might interact with the active center of RdRp. Rifapentine significantly improves the survival rate, alleviates clinical signs, and reduces virus load and injury in targeted organs both in infected A129−/−and normal C57 mice. The antiviral effect is robust during both prophylactic intervention and therapeutic treatment after virus challenge, and the activity is superior to sofosbuvir, a previously reported YFV inhibitor in mice. Our data show that rifapentine may serve as an effective anti-YFV agent, providing promising prospects in the development of YFV pharmacotherapy.
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00326
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00326, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Optical Selection Rule of Excitons in Gapped Chiral Fermion Systems
Creators: name: Zhang, Xiaoou
name: Shan, Wen-Yu
name: Xiao, Di
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We show that the exciton optical selection rule in gapped chiral fermion systems is governed by their winding number $w$, a topological quantity of the Bloch bands. Specifically, in a $C_N$-invariant chiral fermion system, the angular momentum of bright exciton states is given by $w \pm 1 + nN$ with $n$ being an integer. We demonstrate our theory by proposing two chiral fermion systems capable of hosting dark $s$-like excitons: gapped surface states of a topological crystalline insulator with $C_4$ rotational symmetry and biased $3R$-stacked MoS$_2$ bilayers. In the latter case, we show that gating can be used to tune the $s$-like excitons from bright to dark by changing the winding number. Our theory thus provides a pathway to electrical control of optical transitions in two-dimensional material.
description: 8 pages, 4 figures
A Combined EIS-NVSS Survey Of Radio Sources II: Infrared imaging and the K-z relation
Creators: name: Brookes, M. H.
name: Best, P. N.
name: Rengelink, R.
name: Rottgering, H. J. A.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The Combined EIS-NVSS Survey Of Radio Sources (CENSORS) is a 1.4 GHz radio survey selected from the NRAO VLA Sky Survey (NVSS) and complete to a flux-density of 7.2mJy. It targets the ESO Imaging Survey (EIS) Patch D, which is a 3 by 2 square degree field centred on 09 51 36.0 -21 00 00 (J2000). This paper presents K-band imaging of 142 of the 150 CENSORS sources. The primary motivation for beginning infrared imaging of the sample was to identify the host galaxies of the ~30% of sources for which the EIS I-band imaging failed to produce a likely candidate. In addition, K-band magnitudes allow photometric redshift estimation and I - K colours aid the identification of host galaxies (which are typically old, red ellipticals). Of the sources observed in the I and K-bands, four remain undetected, possibly indicating high redshifts for the host galaxies, and eight involve complicated radio structures, or several candidate host galaxies, which have yet to be resolved. Thus, the host galaxy identifications are brought to 92% completeness. In conjunction with spectroscopic observations, the K-band magnitudes have been aperture corrected and used to establish a K-z relation for the CENSORS radio galaxies. This relation is of interest because of its variation, at z > 1, between radio surveys of different flux-density limit. Establishing this relation for CENSORS may shed light on the origin of this variation and will allow an appropriate K-z redshift estimator for any CENSORS source which remains without a spectroscopic redshift. It is shown that whilst the K-z relation for CENSORS is fainter than that of 3CRR at all redshifts, it agrees well with that of 7C over all redshifts studied.
description: Accepted by MNRAS. Replaced in order to correct bibliography problems. A full version, including figures is available at http://www.roe.ac.uk/~pnb/papers/CENSORS_Kband.ps
title: 01_0755
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Iterating Block Spin Transformations of the O(3) Non-Linear Sigma-Model
Creators: name: Gottlob, A. P.
name: Hasenbusch, M.
name: Pinn, K.
Publisher: name: arXiv
Year: 1996
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study the iteration of block spin transformations in the O(3) symmetric non-linear sigma-model on a two-dimensional square lattice with help of the Monte Carlo method. In contrast to the classical Monte Carlo Renormalization Group approach, we do attempt to explicitly compute the block spin effective actions. Using two different methods for the determination of effective couplings, we study the renormalization group flow for various parametrization and truncation schemes. The largest ansatz for the effective action contains thirteen coupling constants. Actions on the renormalized trajectory should describe theories with no lattice artefacts, even at small correlation length. However, tests with the step scaling function of Luescher et al. reveal that our truncated effective actions show sizable scaling violations indicating that the ansaetze are still too small.
description: 29 pages (latex, including 4 postscript figures, uuencoded gz-compressed .tar file 46Kb )
Additional file 1: of Impact of patient involvement on clinical practice guideline development: a parallel group study
Creators: name: Armstrong, Melissa
name: C. Mullins
name: Gronseth, Gary
name: Gagliardi, Anna
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Conceptual model of patient and public contributions to guidelines (Complete). Conceptual model table with all examples extracted from literature (not simply sample quotes as provided in table in the text). (DOCX 22 kb)
Propagating speed waves in flocks: a mathematical model
Creators: name: Cavagna, Andrea
name: Conti, Daniele
name: Giardina, Irene
name: Grigera, Tomas S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Efficient collective response to external perturbations is one of the most striking abilities of a biological system. Signal propagation through the group is an important condition for the imple- mentation of such a response. Information transfer has been experimentally observed in the turning mechanism of birds flocks. In this context it is well-known also the existence of density waves: birds under predation, attempting to escape, give rise to self-organized density waves that propagates linearly on the flock. Most aspects of this phenomenon are still not fully captured by theoretical models. In this work we present a new model for the propagation of the speed (the modulus of the velocity) fluctuations inside a flock, which is the simplest way to reproduce the observed density waves. We have studied the full solution of the model in d = 1 and we found that there is a line in the parameter space along which the system relaxes in the fastest way with no oscillation after a signal has passed. This is the critical damping condition. By analyzing the parameters plane we show that critical damping represents an attractor for a steepest descent dynamics of the return time of the system. Finally we propose a method to test the validity of the model through through future experiments.
Thermal properties and residual stress cracking of boron carbide systems
Creators: name: Henson, Nicholas J.
Publisher: name: No Publisher Supplied
Year: 2023

description: Boron carbide is a material that has been extensively researched for its use as a hard ceramic in armor applications. Its low density and high hardness make it an ideal candidate for ballistic protection materials and Si/B co-doping as well as TiB₂ inclusions have been shown to greatly improve the amorphization resistance and toughness of the material. However when hot pressing Si/B co-doped B₄C it has been observed both in the lab and by industry collaborators that chipping and cracking can sometimes occur upon either unloading or machining of samples. This work seeks to investigate the thermal properties of various boron carbide systems such as thermal conductivity and thermal expansion coefficient to see how these might relate to thermal residual stresses that could cause cracking in the material. It was found that Si/B co-doping led to an increase in thermal expansion coefficient of boron carbide as well as decrease in thermal conductivity. TiB₂ inclusions likewise lead to an increase in thermal expansion but also increased thermal conductivity. Using SEM to analyze doped boron carbide samples a novel observation was made that a silicon deficient band up to 1mm thick forms at the edge of doped boron carbide samples. This in conjunction with the CTE values measured for doped and undoped B₄C allowed for the calculation of a residual stress upon cooling from high temperature at this interface. It was found that even at temperatures as low as 650°C a compressive residual stress equaling that of the flexural strength for doped boron carbide was formed in the outer silicon deficient layer. This combined with the observation that glassy impurity phases have segregated near the diffusion boundary in the region of tensile residual stress mean that CTE mismatch and silicon diffusion is a likely driver of the cracking behavior seen in doped boron carbide.
Searching for new scalar bosons via triple-top signature in $cg \to tS^0 \to tt\bar t$
Creators: name: Kohda, Masaya
name: Modak, Tanmoy
name: Hou, Wei-Shu
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The alignment phenomenon, that the 125 GeV $h^0$ boson so resembles the Standard Model Higgs boson, can be understood in a two Higgs doublet model without discrete symmetry. New Yukawa couplings $ρ_{tt}$ and $ρ_{tc}$ offer new avenues to discover the extra scalar $H^0$ and pseudoscalar $A^0$. We propose to search for $cg \to tH^0$, $tA^0$ followed by $H^0$, $A^0 \to t\bar t$, $t\bar c$, where same-sign dileptons could be the harbinger, with triple-top, in the signature of three leptons plus three $b$-jets, as confirmation. Discovery could touch upon the origin of baryon asymmetry of the Universe.
description: references added, minor modifications, matched with the published version
Preservation of Hydrothermal Fluid Copper Isotope Signatures in Chalcopyrite-Rich Chimneys: A Case Study From the PACMANUS Vent Field, Manus Basin
Creators: name: Samin, Apolline
name: Roerdink, Desiree L.
name: Reeves, Eoghan P.
name: Scheffler, Johannes
name: Bach, Wolfgang
name: Beinlich, Andreas
name: Jamieson, John W.
name: Rouxel, Olivier
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: seafloor hydrothermal systems
subject: copper isotopes
subject: black smoker
subject: chalcopyrite-rich chimney
subject: 500 Naturwissenschaften und Mathematik::550 Geowissenschaften, Geologie::550 Geowissenschaften

description: Copper isotopes (δ65Cu) in hydrothermal fluids have the potential to provide information on ore-forming processes occurring below the seafloor, but Cu isotope data from high-temperature fluids are scarce. Here, we examine the extent to which coexisting sulfide minerals in a hydrothermal chimney can preserve fluid Cu isotope ratios using a fluid-solid pair of a black smoker (333°C) from the Roman Ruins vent area (PACMANUS) in the Manus Basin. Two ca. 3 cm long transects through the chalcopyrite-rich chimney wall show an increase in δ65Cu from 0.48 to 2.28‰ from the interior to the exterior, coupled with limited variation in sulfide δ34S (1.52–4.72‰). The Cu isotopic composition of chalcopyrite from the innermost wall closely resembles the δ65Cu value of the paired hydrothermal fluid, indicating that chalcopyrite in the inner ∼5 mm of the chimney records the Cu isotope ratio of the venting fluid. Beyond this, an increase in sulfide δ65Cu toward the exterior correlates with an increase in the relative abundance of secondary Cu sulfides. The appearance of bornite coincides with the presence of small barite crystals, suggesting this represents a redox gradient between reduced hydrothermal fluids and oxidized seawater admixing inwards. Elevated δ65Cu in this zone can be explained by the precipitation of secondary Cu sulfides from 65Cu-enriched fluids formed during oxidative chalcopyrite dissolution. Our findings indicate that interactions with oxidizing seawater shift chalcopyrite δ65Cu values over small spatial scales, and that caution must be applied if chimney sulfides are used to reconstruct δ65Cu values of high-temperature hydrothermal fluids.
Genomic profiling of extended-spectrum β-lactamase-producing Escherichia coli from Pets in the United Arab Emirates: Unveiling colistin resistance mediated by mcr-1.1 and its probable transmission from chicken meat – A One Health perspective
Creators: name: Habib, Ihab
name: Elbediwi, Mohammed
name: Mohteshamuddin, Khaja
name: Mohamed, Mohamed-Yousif Ibrahim
name: Lakshmi, Glindya Bhagya
name: Abdalla, Afra
name: Anes, Febin
name: Ghazawi, Akela
name: Khan, Mushtaq
name: Khalifa, Hazim
Publisher: name: Freie Universität Berlin
Year: 2023
Subjects: subject: One health
subject: UAE
subject: Resistance
subject: ESBL
subject: Mcr-1
subject: Pets
subject: 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

description: Background The United Arab Emirates (UAE) has witnessed rapid urbanization and a surge in pet ownership, sparking concerns about the possible transfer of antimicrobial resistance (AMR) from pets to humans and the environment. This study delves into the whole-genome sequencing analysis of ESBL-producing E. coli strains from healthy cats and dogs in the UAE, which exhibit multidrug resistance (MDR). Additionally, it provides a genomic exploration of the mobile colistin resistance gene mcr-1.1, marking the first instance of its detection in Middle Eastern pets. Methods We investigate 17 ESBL-producing E. coli strains from healthy UAE pets using WGS and bioinformatics analysis to identify genes encoding virulence factors, assign diverse typing schemes to the isolates, and scrutinize the presence of AMR genes. Furthermore, we characterized plasmid contigs housing the mcr-1.1 gene and conducted phylogenomic analysis to evaluate their relatedness to previously identified UAE isolates. Results Our study unveiled a variety of virulence factor-encoding genes within the isolates, with fimH emerging as the most prevalent. Regarding β-lactamase resistance genes, the blaCTX group 1 gene family predominated, with CTX-M-15 found in 52.9% (9/17) of the isolates, followed by CTX-M-55 in 29.4% (5/17). These isolates were categorized into multiple sequence types (STs), with the epidemic ST131 being the most frequent. The presence of the mcr-1.1 gene, linked to colistin resistance, was confirmed in two isolates. These isolates belonged to ST1011 and displayed distinct profiles of β-lactamase resistance genes. Phylogenomic analysis revealed close connections between the isolates and those from chicken meat in the UAE. Conclusion Our study underscores the presence of MDR ESBL-producing E. coli in UAE pets. The identification of mcr-1.1-carrying isolates warrants the urgency of comprehensive AMR surveillance and highlights the role of companion animals in AMR epidemiology. These findings underscore the significance of adopting a One Health approach to mitigate AMR transmission risks effectively.
Entanglement in the dispersive interaction of trapped ions with a quantized field
Creators: name: Semião, F. L.
name: Furuya, K.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The mode-mode entanglement between trapped ions and cavity fields is investigated in the dispersive regime. We show how a simple initial preparation of Gaussian coherent states and a postselection may be used to generate motional non-local mesoscopic states (NLMS) involving ions in different traps. We also present a study of the entanglement induced by dynamical Stark-shifts considering a cluster of N-trapped ions. In this case, all entanglement is due to the dependence of the Stark-shifts on the ions' state of motion manifested as a cross-Kerr interaction between each ion and the field.
description: 10 pages, 5 figures, corrected typos