cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Entyloma californiensis K. G. Savchenko & Carris 2017, sp. nov.
Creators: name: Savchenko, Kyrylo G.
name: Carris, Lori M.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Exobasidiomycetes
Entylomatales
Entylomataceae
Entyloma
Entyloma californiensis

description: Entyloma californiensis K.G. Savchenko & Carris, sp. nov. (Fig. 1, a–c)
MycoBank: MB 822000
 Type: — USA. California: Armstrong’s Station, El Dorado Co., alt. 1615 m, on Sanicula graveolens (as S. nevadensis), 11 Jun 1895, G. Hansen (BPI 175301, holotype, designated here).
 Diagnosis: Differs from E. saniculae and E. flavoluteum in having swollen and larger sori, mostly confluent spores with thicker spore walls.
Sori in leaves, forming round or elongate to polyangular, amphigenous, flat, scattered or sometimes gregarious, initially white, later pale yellowish-brown spots, 1–10 mm diameter or larger when confluent. Spores confluent, sometimes in chains, globose, subglobose, ovoid, ellipsoidal to slightly irregular, (11) 12–16 × 14–20 (22) μm diameter [av. ± SD, 14.9 ± 1.8 × 16.7 ± 2.9 μm] with subhyaline content. Spore wall 2–6 μm thick, uneven, hyaline to subhyaline, smooth. Anamorph absent.
 Etymology: —Named for the state in which the known specimens were collected.
 Other specimens examined: — USA. California: Little Panther, Amador Co., alt. 1524 m, on Sanicula graveolens (as S. nevadensis), May 1895, G. Hansen (BPI 175302)
description: Published as part of Savchenko, Kyrylo G. & Carris, Lori M., 2017, Two new Entyloma (Entylomataceae, Basidiomycota) species on North American Sanicula, pp. 191-195 in Phytotaxa 327 (2) on page 192, DOI: 10.11646/phytotaxa.327.2.8, http://zenodo.org/record/13723173
title: Promoting the emotional well-being of staff in care homes for older people
Creators: name: Blair, Joanna
Publisher: name: University of Glasgow
Year: 2020
Subjects: subject: Compassion fatigue, compassion satisfaction, care home, manager.

description: Background: Compassion fatigue is associated with negative physical and psychological symptoms. Compassion satisfaction occurs when carers experience reward from helping others. Research has concluded that managerial support can protect against compassion fatigue; however, there is limited evidence exploring how older adult care home managers support their staff. Aims: The study aimed to explore care home managers‟ experiences of mitigating compassion fatigue and promoting compassion satisfaction in their staff teams. Method: Semi-structured interviews were carried out with six care home managers. The interviews were transcribed verbatim and analysed using Interpretive Phenomenological Analysis. Results: Three superordinate themes were developed from the data: 1) Navigating staff-resident relationships; 2) Utilising manager resources; and 3) Promoting satisfaction. Conclusions: The participants described their experiences validating and empathising with staff. They reflected on challenges, the need for relationship-based care, and highlighted staff training needs. Implications and recommendations are discussed.
Entyloma flavoluteum K. G. Savchenko & Carris 2017, sp. nov.
Creators: name: Savchenko, Kyrylo G.
name: Carris, Lori M.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Fungi
Basidiomycota
Exobasidiomycetes
Entylomatales
Entylomataceae
Entyloma
Entyloma flavoluteum

description: Entyloma flavoluteum K.G. Savchenko & Carris, sp. nov. (Fig.1, d–f)
MycoBank: MB 822001
 Type: — USA. California: Santa Cruz Co., Santa Cruz, Lagoon near, on Sanicula crassicaulis (as S. menziesii), Apr 1885, Anonimous (BPI 176517, holotype, designated here).
 Diagnosis:—Differs from E. californiensis by having smaller spores with thinner spore walls, and from E. saniculae by the color of the sori, larger spores and thicker spore walls.
Sori in leaves, forming round or elongate to polyangular, amphigenous, flat, scattered or sometimes gregarious, initially pale yellowish to pale orange spots, 0.2–1 mm diameter or larger when confluent. Spores in small irregular groups, sometimes in chains, globose, subglobose, ovoid, ellipsoidal to slightly irregular, 9–15 × 11.5–17 (18) μm diameter [av. ± SD, 12.6 ± 1.5 × 14.5 ± 2.3 μm] with subhyaline content. Spore wall uniform, 1.5–2.5 μm thick, hyaline to subhyaline, smooth. Anamorphic state present as fascicles of conidia and conidiophores, forming yellowish to pale orange, abaxial cover.
 Etymology: —Named after the yellowish color of the sori.
description: Published as part of Savchenko, Kyrylo G. & Carris, Lori M., 2017, Two new Entyloma (Entylomataceae, Basidiomycota) species on North American Sanicula, pp. 191-195 in Phytotaxa 327 (2) on page 192, DOI: 10.11646/phytotaxa.327.2.8, http://zenodo.org/record/13723173
Segregation-induced changes in grain boundary cohesion and embrittlement in binary alloys
Creators: name: Gibson, Michael A.
name: Schuh, Christopher A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Grain boundary embrittlement occurs when a solute enriches at a grain boundary and lowers its cohesive energy. While grain boundary enrichment is often attributed to equilibrium segregation effects, most models of embrittlement consider either the energetics of decohesion or the equilibrium adsorption at the boundary, but not both phenomena together. We develop a model for the change in cohesive energy of a grain boundary of a pure metal upon introduction of solute under conditions of equilibrium segregation prior to fracture. A heuristic grain boundary cohesion map is presented to delineate whether a given solute-solvent pair will exhibit weakening or strengthening of grain boundaries. The analysis helps to clarify that grain boundary embrittlement requires a solute that will both lower the cohesive energy of the boundary and segregate to it in the first place. The map reasonably captures known metal-metal embrittling pairs.
description: This is a post-print. The typeset version of the article is available from Acta Materialia via Elsevier, along with supplementary csv files
Soft X-ray Temperature Tidal Disruption Events from Stars on Deep Plunging Orbits
Creators: name: Dai, Lixin
name: McKinney, Jonathan C.
name: Miller, M. Coleman
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: One of the puzzles associated with tidal disruption event candidates (TDEs) is that there is a dichotomy between the color temperatures of ${\rm few}\times 10^4$~K for TDEs discovered with optical and UV telescopes, and the color temperatures of ${\rm few}\times 10^5 - 10^6$~K for TDEs discovered with X-ray satellites. Here we propose that high-temperature TDEs are produced when the tidal debris of a disrupted star self-intersects relatively close to the supermassive black hole, in contrast to the more distant self-intersection that leads to lower color temperatures. In particular, we note from simple ballistic considerations that greater apsidal precession in an orbit is the key to closer self-intersection. Thus larger values of $β$, the ratio of the tidal radius to the pericenter distance of the initial orbit, are more likely to lead to higher temperatures of more compact disks which are super-Eddington and geometrically and optically thick. For a given star and $β$, apsidal precession also increases for larger black hole masses, but larger black hole masses imply a lower temperature at the Eddington luminosity. Thus the expected dependence of the temperature on the mass of the black hole is non-monotonic. We find that in order to produce a soft X-ray temperature TDE, a deep plunging stellar orbit with $β> 3$ is needed and a black hole mass of $\lesssim 5\times 10^6 M_\odot$ is favored. Although observations of TDEs are comparatively scarce and are likely dominated by selection effects, it is encouraging that both expectations are consistent with current data.
description: 10 pages, 4 figures, accepted by the Astrophysical Journal Letters
Computable error estimates for finite element approximations of elliptic partial differential equations with rough stochastic data
Creators: name: Hall, Eric Joseph
name: Hoel, Håkon
name: Sandberg, Mattias
name: Szepessy, Anders
name: Tempone, Raúl
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 60H35 (Primary), 65N15, 35R60 (Secondary)

description: We derive computable error estimates for finite element approximations of linear elliptic partial differential equations (PDE) with rough stochastic coefficients. In this setting, the exact solutions contain high frequency content that standard a posteriori error estimates fail to capture. We propose goal-oriented estimates, based on local error indicators, for the pathwise Galerkin and expected quadrature errors committed in standard, continuous, piecewise linear finite element approximations. Derived using easily validated assumptions, these novel estimates can be computed at a relatively low cost and have applications to subsurface flow problems in geophysics where the conductivities are assumed to have lognormal distributions with low regularity. Our theory is supported by numerical experiments on test problems in one and two dimensions.
description: 34 pages, 10 figures. To appear in SISC
Genetic variant rs3750625 in the 3′UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site
Creators: name: Bortsov, Andrey V.
name: Jones, Jeffrey S.
name: Rossi, Catherine
name: Peak, David A.
name: Hu, JunMei
name: Walker, Margaret G.
name: McLean, Samuel A.
name: Nyland, Jennifer E.
name: Swor, Robert A.
name: Linnstaedt, Sarah D.
name: Riker, Kyle D.
name: DIatchenko, Luda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: α2A adrenergic receptor (α2A-AR) activation has been shown in animal models to play an important role in regulating the balance of acute pain inhibition vs. facilitation after both physical and psychological stress. To our knowledge the influence of genetic variants in the gene encoding α2A-AR, ADRA2A, on acute pain outcomes in humans experiencing traumatic stress has not been assessed. In this study, we tested whether a genetic variant in the 3′UTR of ADRA2A, rs3750625, is associated with acute musculoskeletal pain (MSP) severity following motor vehicle collision (MVC, n = 948) and sexual assault (n = 84), and whether this influence was affected by stress severity. We evaluated rs3750625 because it is located in the seed binding region of miR-34a, a microRNA (miRNA) known to regulate pain and stress responses. In both cohorts, the minor allele at rs3750625 was associated with increased MSP in distressed individuals (stress*rs3750625 p = 0.043 for MVC cohort and p = 0.007 for sexual assault cohort). We further found that (1) miR-34a binds the 3′UTR of ADRA2A, (2) the amount of repression is greater when the minor (risk) allele is present, (3) miR-34a in the IMR-32 adrenergic neuroblastoma cell line affects ADRA2A expression, (4) miR-34a and ADRA2A are expressed in tissues known to play a role in pain and stress, (5) following forced swim stress exposure, rat peripheral nerve tissue expression changes are consistent with miR-34a regulation of ADRA2A. Together these results suggest that ADRA2A rs3750625 contributes to post-stress MSP severity by modulating miR-34a regulation.
Persistent pain after motor vehicle collision: comparative effectiveness of opioids vs nonsteroidal antiinflammatory drugs prescribed from the emergency department—a propensity matched analysis
Creators: name: Swor, Robert A.
name: Jones, Jeffrey S.
name: McLean, Samuel A.
name: Clark, Melissa A.
name: Lee, David C.
name: Rathlev, Niels K.
name: Peak, David A.
name: Gutman, Roee
name: Merchant, Roland C.
name: Domeier, Robert M.
name: Beaudoin, Francesca L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Each year millions of Americans present to the emergency department (ED) for care after a motor vehicle collision (MVC), the great majority (>90%) are discharged to home after evaluation. Acute musculoskeletal pain is the norm in this population, and such patients are typically discharged to home with prescriptions for oral opioid analgesics or non-steroidal anti-inflammatory drugs (NSAIDs). The influence of acute pain management on subsequent pain outcomes in this common ED population is unknown. We evaluated the effect of opioid analgesics versus NSAIDs initiated from the ED on the presence of moderate to severe musculoskeletal pain and ongoing opioid use at 6 weeks in a large cohort of adult ED patients presenting to the ED after MVC (n=948). The effect of opioids versus NSAIDs was evaluated using an innovative quasi-experimental design method using propensity scores to account for covariate imbalances between the two treatment groups. No difference in risk for moderate to severe musculoskeletal pain at six weeks was observed between those discharged with opioid analgesics versus NSAIDS (Risk Difference = 7.2% (95% CI: -5.2,19.5%). However, at follow-up participants prescribed opioids were more likely than those prescribed NSAIDS to report use of prescription opioids medications at week 6 (Risk Difference = 17.5% (95% CI: 5.8,29.3%). These results suggest that analgesic choice at ED discharge does not influence the development of persistent moderate to severe musculoskeletal pain six weeks after an MVC, but may result in continued use of prescription opioids.
Two schemes for characterization and detection of the squeezed light: Dynamical Casimir effect and nonlinear materials
Creators: name: Lotfipour, H.
name: Allameh, Z.
name: Roknizadeh, R.
name: Heydari, H.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The detection and characterization of a non-classical-squeezed state of light, by using two different schemes, will be presented . In the first one, in an one-dimensional cavity with moving mirror (non-stationary Casimir effect) in the principal mode, we study the photon creation rate for two modes (squeezed and coherent state) of driving field. Since the cavity with moving mirror (similar to an optomechanical system) can be considered analogue to a Kerr-like medium, so that in the second scheme, the probability amplitude for multi-photons absorption in a nonlinear (Kerr) medium will be quantum mechanically calculated. It is shown that because of presence of nonlinear effects, the responses of these two systems to the squeezed versus coherent state are considerably distinguishable. The drastic difference between the results of these two states of light can be viewed as a proposal for detecting of non-classical states.
Monthly plant moisture stress measurements from the lower slopes of the Langrivier Catchment, Jonkershoek, site 3318DD/8/106
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
Plant Moisture Stress
Jonkershoek
Kiggelaria africana

description: This is a scanned copy of a document noting monthly plant moisture stress measurements from Kiggelaria africana on the lower slopes of the Langrivier Catchment, Jonkershoek, site 3318DD/8/106. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
PKC [epsilon] mediates pain and aversive states evoked by opioid withdrawal
Creators: name: Gregory Flores, Adriana
name: 0000-0002-9315-4345
Publisher: name: The University of Texas at Austin
Year: 2022
Subjects: Opioid withdrawal-induced hyperalgesia
Paclitaxel-induced hyperalgesia
Morphine self-administration
Aversive states

description: Aggressive marketing and increased prescribing of opioids for treating pain have fueled a prominent increase in misuse of opioids. This acute public health problem has led to calls for non-opioid alternatives to treat chronic pain. The enzyme protein kinase C epsilon (PKCε) in plays a role in the transition from acute to chronic pain. Here we investigated the role of a novel PKCε inhibitor in a preclinical rodent model of paclitaxel-induced hyperalgesia, a model of chemotherapy induced neuropathic pain previously shown to be PKCε dependent. Because the transition of opioid-dependent individuals to a non-opioid pain medication could provoke opioid withdrawal we also investigated whether the PKCε inhibitor alters opioid withdrawal-induced pain and conditioned place aversion, and opioid self-administration . Our findings showed that PKCε inhibition attenuated paclitaxel-induced hyperalgesia, opioid withdrawal-induced hyperalgesia, and somatic signs of opioid withdrawal. It did not block conditioned place aversion produced by opioid withdrawal and not modify the addictive potential of morphine in a self-administration procedure. The PKCε inhibitor was no self-administered suggesting it has no addictive potential. These findings suggest that PKCε inhibition is an effective non-addictive medication to treat paclitaxel-induced hyperalgesia with the added of benefit of limiting several features of opioid withdrawal, which could facilitate treatment of chronic pain in opioid dependent individuals.
Radiation pattern of two identical emitters driven by a Laguerre-Gaussian beam: An atom nanoantenna
Creators: name: Lembessis, Vassilis E.
name: Lyras, Andreas
name: Rsheed, Anwar Al
name: Aldossary, Omar M.
name: Ficek, Zbigniew
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the directional properties of a radiation field emitted by a geometrically small system composed of two identical two-level emitters located at short distances and driven by an optical vortex beam, a Laguerre-Gaussian beam which possesses a structured phase and amplitude. We find that the system may operate as a nanoantenna for controlled and tunable directional emission. Polar diagrams of the radiation intensity are presented showing that a constant phase or amplitude difference at the positions of the emitters plays an essential role in the directivity of the emission. We find that the radiation patterns may differ dramatically for different phase and amplitude differences at the positions of the emitters. As a result the system may operate as a two- or one-sided nanoantenna. In particular, a two-sided highly focused directional emission can be achieved when the emitters experience the same amplitude and a constant phase difference of the driving field. We find a general directional property of the emitted field that when the phase differences at the positions of the emitters equal an even multiple of π/4, the system behaves as a two-sided antenna. When the phase difference equals an odd multiple of π/4, the system behaves as an one-sided antenna. The case when the emitters experience the same phase but different amplitudes of the driving field is also considered and it is found that the effect of different amplitudes is to cause the system to behave as a uni-directional antenna radiating along the interatomic axis.
description: published version
Evidence for resonant scattering of electrons by spin fluctuations in $LaNiO_3/LaAlO_3$ heterostructures grown by pulsed laser deposition
Creators: name: Sergeenkov, S.
name: Cichetto,, L.
name: Longo, E.
name: Araujo-Moreira, F. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We present measurements of resistivity $ρ$ in highly oriented $LaNiO_3$ films grown on $LaAlO_3$ substrates by using a pulsed laser deposition technique. The experimental data are found to follow a universal $ρ(T) \propto T^{3/2}$ dependence for the entire temperature interval ($20K
description: Accepted for publication in JETP Letters
Temporal change in headache and its contribution to the risk of developing first-onset temporomandibular disorder in the Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) study
Creators: name: Maixner, William
name: Greenspan, Joel D.
name: Fillingim, Roger B.
name: Tchivileva, Inna E.
name: Ohrbach, Richard
name: Slade, Gary D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: While cross-sectional studies have demonstrated an association between headache and temporomandibular disorder (TMD), whether headache can predict the onset of TMD is unknown. The aims of this study were to evaluate the contribution of headache to the risk of developing TMD and describe patterns of change in headache types over time. An initially TMD-free cohort of 2410 persons with low frequency of headache completed quarterly questionnaires assessing TMD and headache symptoms over a median 3.0-year follow-up period. First-onset TMD was confirmed by clinical examination in 199 participants. Baseline reports of migraine (hazard ratio [HR] = 1.67, 95% confidence interval [CI]: 1.06-2.62) or mixed headache types (HR = 4.11, 95% CI: 1.47-11.46), or headache frequency (HR = 2.13, 95% CI: 1.31-3.48) predicted increased risk of developing TMD. In addition, headache dynamics across the follow-up period before the TMD onset were evaluated in a nested case-control study where 248 incident TMD cases were matched to 191 TMD-free controls. Both headache prevalence and frequency increased across the observation period among those who developed TMD but not among controls. Patients with TMD were more likely to experience worsening in the headache type compared with that by controls, eg, prevalence of definite migraine among TMD cases increased 10-fold. Among all headache types experienced by patients with TMD before the TMD onset, migraine had the highest odds of progression relative to remission (odds ratio = 2.8, 95% CI: 1.6-4.8), whereas for controls this ratio was significant only for the tension-type headache (odds ratio = 2.1, 95% CI: 1.2-3.9). The important clinical implication of these findings is that adequate treatment of migraine may reduce the risk for developing TMD.
Supplementary Appendix GAD65Abs are not associated with beta-cell dysfunction in patients with T2D in the GRADE Study
Creators: name: Hampe, CS
name: Shojaie, A
name: Brooks-Worrell, B
name: Dibay, S
name: Utzschneider, K
name: Kahn, SE
name: Larkin, ME
name: Johnson, ML
name: Younes, N
name: Resouli, N
name: Desouza, C
name: Cohen, RM
name: Park, JY
name: Florez, HJ
name: Valencia, WM
name: Palmer, JP
name: Balasubramanyam, A
Publisher: name: Zenodo
Year: 2023
Subjects: islet autoantibodies, epitope-specific autoantibodies, anti-idiotypic antibodies, T cell-mediated autoimmunity, humoral autoimmunity, latent autoimmune diabetes of adults

description: Supplemental material for manuscript submitted to JCEM.
A Deep Learning Approach to Structured Signal Recovery
Creators: name: Mousavi, Ali
name: Patel, Ankit B.
name: Baraniuk, Richard G.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: In this paper, we develop a new framework for sensing and recovering structured signals. In contrast to compressive sensing (CS) systems that employ linear measurements, sparse representations, and computationally complex convex/greedy algorithms, we introduce a deep learning framework that supports both linear and mildly nonlinear measurements, that learns a structured representation from training data, and that efficiently computes a signal estimate. In particular, we apply a stacked denoising autoencoder (SDA), as an unsupervised feature learner. SDA enables us to capture statistical dependencies between the different elements of certain signals and improve signal recovery performance as compared to the CS approach.
Cohort Study of the Impact of High-Dose Opioid Analgesics on Overdose Mortality
Creators: name: Hirsch, Annie
name: Ribisl, Kurt M.
name: Funk, Michele Jonsson
name: Marshall, Steve
name: Dasgupta, Nabarun
name: Proescholdbell, Scott
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: OBJECTIVE: Previous studies examining opioid dose and overdose risk provide limited granularity by milligram strength and instead rely on thresholds. We quantify dose-dependent overdose mortality over a large spectrum of clinically common doses. We also examine the contributions of benzodiazepines and extended release opioid formulations to mortality.

DESIGN: Prospective observational cohort with one year follow-up.

SETTING: One year in one state (NC) using a controlled substances prescription monitoring program, with name-linked mortality data.

SUBJECTS: Residential population of North Carolina (n = 9,560,234), with 2,182,374 opioid analgesic patients.

METHODS: Exposure was dispensed prescriptions of solid oral and transdermal opioid analgesics; person-years calculated using intent-to-treat principles. Outcome was overdose deaths involving opioid analgesics in a primary or additive role. Poisson models were created, implemented using generalized estimating equations.

RESULTS: Opioid analgesics were dispensed to 22.8% of residents. Among licensed clinicians, 89.6% prescribed opioid analgesics, and 40.0% prescribed ER formulations. There were 629 overdose deaths, half of which had an opioid analgesic prescription active on the day of death. Of 2,182,374 patients prescribed opioids, 478 overdose deaths were reported (0.022% per year). Mortality rates increased gradually across the range of average daily milligrams of morphine equivalents. 80.0% of opioid analgesic patients also received benzodiazepines. Rates of overdose death among those co-dispensed benzodiazepines and opioid analgesics were ten times higher (7.0 per 10,000 person-years, 95 percent CI: 6.3, 7.8) than opioid analgesics alone (0.7 per 10,000 person years, 95 percent CI: 0.6, 0.9).

CONCLUSIONS: Dose-dependent opioid overdose risk among patients increased gradually and did not show evidence of a distinct risk threshold. There is urgent need for guidance about combined classes of medicines to facilitate a better balance between pain relief and overdose risk.
Does Attendance at a Sickle Cell Educational Conference Improve Clinician Knowledge and Attitude Toward Patients with Sickle Cell Disease?
Creators: name: Jenerette, Coretta M.
name: Silva, Susan
name: Tanabe, Paula
name: Brewer, Cheryl A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Sickle cell disease (SCD) is a genetic disease associated with both chronic pain and acute painful events referred to as vaso-occlusive crisis. Individuals suffer from a multitude of medical complications in addition to pain. Patients are often stigmatized as “drug-seeking” and receive inadequate pain management.
title: Electrical Equipment Industry Cluster
Creators: name: Gautam, Pragati
Publisher: name: Old Dominion University Libraries
Year: 2022

description: The growing collaboration between two or more industries in a specific region in which they work in a symbiotic relationship, providing benefits to each other and contributing in the overall development of the region, is what is popularly known as business clusters. Even though this concept is commonly known and implemented in the West, South Asian economies are unfamiliar with the advantages of this unique business strategy. There are, undeniably, many potential business clusters in these developing countries, which if tapped efficiently, could result into an industrial boom.

This research focuses on investigating the existence of a business cluster in the electrical equipment sector in Faridabad, a city that shares its borders with the capital city of India (New Delhi). The research relies on an already developed formula from Professor Fregoso Jasso’s 2010 paper to confirm whether there exists a business cluster or not. Developing of a business cluster in the afore mentioned area would result in increased employment and ultimately, higher living standards for the people of the district.
Assessing elemental ratios as a paleotemperature proxy in the calcite shells of patelloid limpets
Creators: name: Gillikin,
name: Álvarez,
name: Graniero,
name: Surge,
name: Briz i Godino,
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Archaeological shell and fish middens are rich sources of paleoenvironmental proxy data. Patelloid limpet shells are common constituents in archaeological middens found along European, African, and South American coastlines. Paleotemperature reconstructions using oxygen isotope ratios of limpet shells depend on the ability to constrain the oxygen isotope ratio of seawater; therefore, alternative proxies are necessary for coastal localities where this is not possible. The study evaluates whether Mg/Ca, Sr/Ca, Li/Ca, Li/Mg, and Sr/Li ratios are reliable proxies of sea surface temperature (SST) in the calcite layer of shells of the patelloid limpets, Patella vulgata and Nacella deaurata. We compare Mg/Ca, Sr/Ca, Li/Ca, Li/Mg, and Sr/Li ratios to the seasonal variations in contemporaneous Î´18Oshell values, which primarily record seasonal changes in SST. Elemental ratios (Mg/Ca, Sr/Ca, Li/Ca, Li/Mg, and Sr/Li) show no significant correlations with reconstructed SST in P. vulgata and N. deaurata shells, nor do they show sinusoidal cycles expected from a SST proxy. In addition, shell Î´13C values show no significant ontogenetic trends, suggesting that these limpets exhibit little change in metabolic carbon incorporation into the shell with increasing ontogenetic age. Although shell growth rate exhibits a logarithmic decrease with age based on calculated linear extension rates, growth rate does not correlate with elemental profiles in these limpets. Overall, elem
CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation.
Creators: name: Patel, Avnish
name: Nofal, Stephanie D
name: Blackman, Michael J
name: Baker, David A
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Model organisms
subject: Biochemistry & Proteomics
subject: Structural Biology & Biophysics
subject: Cell Biology
subject: Infectious Disease
subject: Immunology
subject: FOS: Clinical medicine

description: In model organisms, type IV ATPases (P4-ATPases) require cell division control protein 50 (CDC50) chaperones for their phospholipid flipping activity. In the malaria parasite Plasmodium falciparum, guanylyl cyclase alpha (GCα) is an integral membrane protein that is essential for release (egress) of merozoites from their host erythrocytes. GCα is unusual in that it contains both a C-terminal cyclase domain and an N-terminal P4-ATPase domain of unknown function. We sought to investigate whether any of the three CDC50 orthologues (termed A, B, and C) encoded by P. falciparum are required for GCα function. Using gene tagging and conditional gene disruption, we demonstrate that CDC50B and CDC50C but not CDC50A are expressed in the clinically important asexual blood stages and that CDC50B is a binding partner of GCα whereas CDC50C is the binding partner of another putative P4-ATPase, phospholipid-transporting ATPase 2 (ATP2). Our findings indicate that CDC50B has no essential role for intraerythrocytic parasite maturation but modulates the rate of parasite egress by interacting with GCα for optimal cGMP synthesis. In contrast, CDC50C is essential for blood stage trophozoite maturation. Additionally, we find that the CDC50C-ATP2 complex may influence parasite endocytosis of host cell hemoglobin and consequently hemozoin formation. IMPORTANCE Malaria morbidity arises due to successive rounds of replication of Plasmodium parasites within red blood cells. Mature daughter merozoites are released from infected erythrocytes to invade new cells in a tightly regulated process termed egress. Previous studies have shown that a unique bifunctional guanylyl cyclase, GCα, initiates egress by synthesis of cGMP. GCα has an N-terminal P4-ATPase domain of unknown function. In model organisms, P4-ATPases function through interaction with a CDC50 partner protein. Here, we investigate the role of CDC50 orthologues in P. falciparum and show that GCα binds CDC50B, an interaction that regulates egress efficiency. We also find that CDC50C is essential and binds a putative P4-ATPase, ATP2, in a complex that influences endocytosis of host hemaglobin. Our results highlight the heterogenous and critical role of CDC50 proteins in P. falciparum.
Rematerializing Graphs: Learning Spatial Configuration
Creators: name: Stesney, Michael
Publisher: name: Carnegie Mellon University
Year: 2022
Subjects: subject: 120101 Architectural Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: In architecture, recent developments in machine learning technologies have reenergized the established research areas of generative design and design analysis. Proponents argue that data-driven systems can learn the implicit rules of architectural design for the generation of new designs or the incorporation into new methods of architectural research and analysis. This recent research has focused primarily on machine learning model development, in particular the algorithms, but not the data from which the models learn. However, without a concurrent reflection on the data and the representations used to encode the data, a critical understanding of the affordances and limitations of data-driven machine learning tools in architecture is not possible. Therefore, in this research I interrogate the data with a focus on graph-based representations of spatial organizations. As a research method, I present the theoretical concepts tying graphs to computational design theory to selected cutting-edge graph-based and data-driven generative and analytical approaches. I also reconstruct an example of early generative design software and create computational instruments to explore, demonstrate and evaluate the concepts presented in the literature research. Placing recent analytical and generative techniques in the lineage of graph-based representations demonstrates how the motivations of the early theorists, and limitations of graph representations themselves, are carried forward into the machine learning context. Further, investigating the floor plan data sets essential to these technologies reveals the inherently contingent nature of graph-based architectural data, and by extension, the contingency of the results.
A Construction of Non-Kähler Calabi-Yau Manifolds and New Solutions to the Strominger System
Creators: name: Fei, Teng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: High Energy Physics - Theory (hep-th)
subject: Mathematical Physics (math-ph)
subject: Algebraic Geometry (math.AG)
subject: Complex Variables (math.CV)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: We propose a new construction of compact non-Kähler Calabi-Yau manifolds with balanced metrics and study the Strominger system on them. In particular, we obtain explicit solutions to the Strominger system with degeneracies on $Σ_g\times T^4$, where $Σ_g$ is an immersed minimal surface of genus $g\geq3$ in $T^3$.
description: 17 pages, comments are welcome! Updates in v2: small revisions with new references added
Intrareef variations in Li/Mg and Sr/Ca sea surface temperature proxies in the Caribbean reef-building coral Siderastrea siderea : Intrareef Variations in SST Proxies
Creators: name: Fowell, Sara E.
name: Foster, Gavin L.
name: Sandford, Kate
name: Castillo, Karl D.
name: Stewart, Joseph A.
name: Ries, Justin B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Caribbean sea surface temperatures (SSTs) have increased at a rate of 0.2°C per decade since 1971, a rate double that of the mean global change. Recent investigations of the coral Siderastrea siderea on the Belize Mesoamerican Barrier Reef System (MBRS) have demonstrated that warming over the last 30 years has had a detrimental impact on calcification. Instrumental temperature records in this region are sparse, making it necessary to reconstruct longer SST records indirectly through geochemical temperature proxies. Here we investigate the skeletal Sr/Ca and Li/Mg ratios of S. siderea from two distinct reef zones (forereef and backreef) of the MBRS. Our field calibrations of S. siderea show that Li/Mg and Sr/Ca ratios are well correlated with temperature, although both ratios are 3 times more sensitive to temperature change in the forereef than in the backreef. These differences suggest that a secondary parameter also influences these SST proxies, highlighting the importance for site- and species-specific SST calibrations. Application of these paleothermometers to downcore samples reveals highly uncertain reconstructed temperatures in backreef coral, but well-matched reconstructed temperatures in forereef coral, both between Sr/Ca-SSTs and Li/Mg-SSTs, and in comparison to the Hadley Centre Sea Ice and Sea Surface Temperature record. Reconstructions generated from a combined Sr/Ca and Li/Mg multiproxy calibration improve the precision of these SST reconstructions. This result confirms that there are circumstances in which both Li/Mg and Sr/Ca are reliable as stand-alone and combined proxies of sea surface temperature. However, the results also highlight that high-precision, site-specific calibrations remain critical for reconstructing accurate SSTs from coral-based elemental proxies.
Keeping in Touch: Situating myself amidst the incomprehensible systems of the modern world through intimate, everyday interactions
Creators: name: Khurana, Malika
Publisher: name: Carnegie Mellon University
Year: 2022
Subjects: subject: 120304 Digital and Interaction Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: In our modern world of networks, sensors, and interfaces, there is a promise that technology will allow us to connect to others and better understand and predict the world around us. Our digital tools manage our experience of time, space, and relationships to make them supposedly better: efficient, seamless, and accessible. In that convenience, we stop effortfully orienting and noticing for ourselves, and grow disconnected from phenomena around us. Rather than striving for interactions that are so seamless that we do not feel or register anything, we need to create more seams in how we experience the world: the way we mark months, perceive global-scale distances, and/or check the time of day. These seams give us opportunities to stay engaged and anchor ourselves in time and space through our relationships with the natural world and other people. In this thesis, I outline my criteria for experiences that create these anchoring opportunities, as a directive for this project and my future work. I design three intimate, daily interactions with a situated and embodied approach, to anchor myself in the relationships and contexts in which I am entangled. I enable myself to participate in the passage of time with a textile calendar that I unravel each day, direct my thoughts to loved ones in other parts of the world through an orientation-based radio, and reference the time of day through a web application that shows a photograph of the sky. I find that the interactions that ask for some effort from myself, through physical movement, time, and attention, are most enriching and anchoring. The craft of designing interactions that ask something of a person, without feeling like work, requires nuance and understanding that this thesis explores in detail.
Direct theoretical evidence for weaker correlations in electron-doped and Hg-based hole-doped cuprates
Creators: name: Jang, Seung Woo
name: Sakakibara, Hirofumi
name: Kino, Hiori
name: Kotani, Takao
name: Kuroki, Kazuhiko
name: Han, Myung Joon
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Many important questions for high-$T_c$ cuprates are closely related to the insulating nature of parent compounds. While there has been intensive discussion on this issue, all arguments rely strongly on, or are closely related to, the correlation strength of the materials. Clear understanding has been seriously hampered by the absence of a direct measure of this interaction, traditionally denoted by $U$. Here, we report a first-principles estimation of $U$ for several different types of cuprates. The $U$ values clearly increase as a function of the inverse bond distance between apical oxygen and copper. Our results show that the electron-doped cuprates are less correlated than their hole-doped counterparts, which supports the Slater picture rather than the Mott picture. Further, the $U$ values significantly vary even among the hole-doped families. The correlation strengths of the Hg-cuprates are noticeably weaker than that of La$_2$CuO$_4$. Our results suggest that the strong correlation enough to induce Mott gap may not be a prerequisite for the high-$T_c$ superconductivity.
description: Scientific Reports (accepted). The values are updated by the re-calculations of higher accuracy. More parameters now provided in Suppl. Info
Line intercept in Langeberg East, Phezantefontein, site 3321CC/5
Creators: name: Jonkershoek Forestry Research Center
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: Jonkershoek Forestry Research Centre
line intercept
Langeberg East
Phezantefontein

description: This is a scanned copy of a line intercept in Langeberg East, Phezantefontein, site 3321CC/5. The Jonkershoek Forestry Research Center (part of the former South African Forestry Research Institute) was established in 1935 at Jonkershoek, near Stellenbosch, under the directorship of Dr C. L. Wicht. The initial aim was to determine how forestry activities in state plantations would affect climate, water conservation and erosion, and was later expanded to include studies of fynbos ecology, fire and alien species. Studies from the 1930s to the early 1990s saw the accumulation of a large amount of data dealing with fire experiments, detailed vegetation plot surveys, rare plant surveys and ecological studies, hydrological studies and the development of management plans for catchments around the Western Cape. SAEON now houses the archive of data collected by the Jonkershoek Forestry Research Center, which was originally held by the Council for Scientific and Industrial Research (CSIR).
Designing with Senses: Creating Interactive Multisensory Experiences in Public Space
Creators: name: Dong, Yanwen
Publisher: name: Carnegie Mellon University
Year: 2022
Subjects: subject: 129999 Built Environment and Design not elsewhere classified
subject: FOS: Civil engineering
subject: 120304 Digital and Interaction Design
subject: FOS: Arts (arts, history of arts, performing arts, music)

description: Public spaces are made to be shared and accessible to the general public. As spaces for social lives and activities, public spaces act as the platform for spontaneous events to temporarily connect people. They are engaged with almost all human senses, including the five basic senses – sight, sound, smell, taste, and touch – and along with the bodily senses of proprioception and kinaesthesia. This thesis proposes the inquiry of how to prompt new ways of social interaction in public space through multisensory digital experiences. Through establishing contextual information on public space, sensory and multisensory perception and studying research and design precedents that follow sensory design. This thesis then identifies potential design opportunities and begins with on site observation and pilot prototypes to experiment with modes of interaction and participation. After reflecting on the initial explorations, I produced two redesigned prototypes — an interactive sound-material interface that uses artificial grass to defamiliarize natural materials, and a computer vision enabled sand table interface for sound composition.
title: New organic coatings
Creators: name: Ashton, H. E.
Publisher: name: National Research Council of Canada. Division of Building Research
Year: 1966
Subjects: subject: Buildings
valueUri: urn:ircsubjects:IRC0721
subject: Bâtiments
valueUri: urn:ircsubjects:IRC0721
subject: paints
subject: peinture (produit)
subject: alkyd paints
subject: peinture alkyd
subject: vinyl paints
subject: peinture au vinyle
subject: acrylic paints
subject: peinture acrylique
subject: epoxy coatings
subject: enduit à l'époxy
subject: polyester paints
subject: peinture au polyester
subject: urethane coatings
subject: enduit à l'uréthane

description: Coatings which have become commercially important in the past two decades are described. The advantages and disadvantages resulting from their composition are discussed.
Supplementary documentation for SAEON's field instrument data collected at the MSELENI MABASA_DWAS station
Creators: name: South African Environmental Observation Network (SAEON) Grasslands-Forests-Wetlands Node
Publisher: name: South African Environmental Observation Network
Year: 2022
Subjects: SAEON field instruments
Standard Operating Procedures
Calibration
Mseleni
Hydrological
Pressure transducer
Ground Water level

description: This package contains supporting information for the hydrological data collected at MSELENI's MABASA_DWAS station, as part of the South African Environmental Observation Network's monitoring projects.
On the Computation of Form Factors in Massless QCD with Finite Master Integrals
Creators: name: von Manteuffel, Andreas
name: Panzer, Erik
name: Schabinger, Robert M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present the bare one-, two-, and three-loop form factors in massless Quantum Chromodynamics as linear combinations of finite master integrals. Using symbolic integration, we compute their $ε$ expansions and thereby reproduce all known results with an independent method. Remarkably, in our finite basis, only integrals with a less-than-maximal number of propagators contribute to the cusp anomalous dimensions. We report on indications of this phenomenon at four loops, including the result for a finite, irreducible, twelve-propagator form factor integral. Together with this article, we provide our automated software setup for the computation of finite master integrals.
description: 28 pages, 3 figures, results and software in ancillary files; v2: fixed diagram in (7.1); v3: added acknowledgement