cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Adaptive control of synchronization in delay-coupled heterogeneous networks of FitzHugh-Nagumo nodes
Creators: name: Plotnikov, S. A.
name: Lehnert, J.
name: Fradkov, A. L.
name: Schöll, E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: FOS: Physical sciences

description: We study synchronization in delay-coupled neural networks of heterogeneous nodes. It is well known that heterogeneities in the nodes hinder synchronization when becoming too large. We show that an adaptive tuning of the overall coupling strength can be used to counteract the effect of the heterogeneity. Our adaptive controller is demonstrated on ring networks of FitzHugh-Nagumo systems which are paradigmatic for excitable dynamics but can also -- depending on the system parameters -- exhibit self-sustained periodic firing. We show that the adaptively tuned time-delayed coupling enables synchronization even if parameter heterogeneities are so large that excitable nodes coexist with oscillatory ones.
MANIFESTAÇÕES ORAIS NA HANSENÍASE: UMA REVISÃO DE ESCOPO
Creators: name: Da Silveira, Josimar Santorio
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Medicine and Health Sciences
subject: Diseases
subject: Dentistry
subject: FOS: Clinical medicine
subject: Public Health
subject: Hanseníase, Manifestações orais, Odontologia, Revisão de escopo.

description: Leprosy is a chronic granulomatous infectious disease caused by a slow-growing, acid-resistant bacillus, Mycobacterium leprae, which has a specific tropism for the skin, peripheral nerves and mucous membranes, mainly the transmitted tract, and may also affect other organs, such as the liver, testicles, eyes and oral mucosa. The objective of this work was to map the scientific evidence related to the characteristics of oral manifestations in leprosy. This is a scope review. The protocol used for this review was that of the “Joanna Briggs Institute” (JBI). From the search for studies in the databases PUBMED, LILACS, EMBASE, WEB OF SCIENCE, SCOPUS and INFOLEP 2037, articles were found, among which, after selection, 29 were included in this review. Among the articles included, or year of publication varied between 1969 and 2021, most articles (N=12) were found in the PUBMED database and the predominant type of study was case report (N=12) followed by cross-sectional study (N=9). This review found that the age range ranged from 8 to 88 years, most cases were male. Leprosy can involve lesions in the oral mucosa, the most common sites being: tongue, hard palate, soft palate, gingiva, oral mucosa, uvula and lips. The types of lesions vary between: nodules, ulcers, fissures, erythema, hyperpigmentation and whitish plaques. The most common clinical form was Virchowian, followed by Tuberculoid and Indeterminate. The oral manifestations of leprosy have a direct impact on their quality of life, coexistence in society and difficulty in acceptance related to self-image. Dental examinations are low-cost and preventive prevention tools that can be tailored to clinical guidelines for new cases, under treatment or follow-up. The impact of the otorhinolaryngological and oral manifestations of leprosy on the patient's quality of life must be considered.
Outcome measures in phonological treatment (Smit et al., 2018)
Creators: name: Smit, Ann Bosma
name: Klaire Mann Brumbaugh
name: Weltsch, Barbara
name: Hilgers, Melanie
Publisher: name: Figshare
Year: 2018
Subjects: subject: 170204 Linguistic Processes (incl. Speech Production and Comprehension)
subject: FOS: Psychology
subject: Language

description: Purpose: In a feasibility study for a randomized controlled trial of treatments for phonological disorders conducted over a period of 8 months, we examined 6 clinically relevant outcome measures. We took steps to reduce error variance and to maximize systematic variance.Method: Six children received traditional treatment (Van Riper, 1939), and 7 received expansion points (Smit, 2000), a treatment program with both phonological and traditional elements. Outcome measures, which were applied to both word list and conversational samples, included percentage of consonants correct (PCC; Shriberg & Kwiatkowski, 1982), PCC for late and/or difficult (L /D) consonants and number of L/D consonants acquired.Results: In repeated-measures analyses of variance, all measures showed significant differences from pretreatment to posttreatment, and the word list measures were associated with very high power values. In analyses of covariance for between-groups contrasts, the adjusted expansion points mean exceeded the adjusted traditional treatment mean for every measure; however, no differences reached significance. For the L /D PCC (conversation) measure, the contrastbetween groups was associated with a large effect size.Conclusion: We recommend that practitioners use outcome measures related to a word list. We recommend that researchers consider using L/D PCC on the basis of conversational samples to detect differences among treatment groups.
Supplemental Material S1. Ancillary analyses.
Smit, A. B., Brumbaugh, K. M., Weltsch, B., & Hilgers, M. (2018). Treatment of phonological disorder: A feasibility study with focus on outcome measures. American Journal of Speech-Language Pathology, 27, 553–565. https://doi.org/10.1044/2017_AJSLP-16-0225
A Meta-Analysis of Clinical Outcomes of Transcatheter Aortic Valve Replacement in Patients with End Stage Renal Disease
Creators: name: Amione-Guerra, Javier
name: Mattathil, Stephanie
name: Prasad, Anand
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Background: ESRD is associated with an increased incidence of severe aortic stenosis. For these patients the usual care has been surgical aortic valve replacement (SAVR). ESRD patients are at increased surgical risk. TAVR may be an alternative to SAVR for these patients. However, TAVR trials have excluded patients with ESRD. Methods: MEDLINE, OMBASE and Cochrane databases were queried for relevant studies. A meta-analysis was performed on the selected studies. Primary outcome was early all-cause mortality; secondary outcomes included 1-year mortality, bleeding, neurological deficits, vascular complications, pacemaker requirement and myocardial infarction. Results: A total of 16 studies that included 3,499 patients. Most patients were high risk as demonstrated by STS scores > 10 in most studies. Post-TAVR early and 1-year mortality were 10%(95%CI: 7.8–10.5%) and 33%(95%CI: 24.1–36.8%) respectively. Most common post-procedure complications were bleeding 17%(95%CI: 14.8–20.8%), pacemaker implant 14%(95%CI: 11.6–17.5%) and vascular complications 7%(95%CI: 4.3–9.9%). Neurological deficits and myocardial infarction were less common both at 1.2%(95%CI: 0.4 – 2.4%, 0.3 – 2.5% respectively). Three studies with 2,545 patients compared TAVR vs. SAVR, there was no difference in early mortality(~ 10%, RR:1.0, 95%CI 0.60 – 1.64, p = 0.9). TAVR was associated with decreased risk of vascular complications (RR:0.58 95%CI: 0.3 – 0.8, p = 0.03). Conclusions: These results suggest that TAVR outcomes in ESRD patients are comparable to those patients considered extreme surgical risk. Compared to SAVR, there was no difference in early mortality, but fewer vascular complications. As the ESRD population continues to grow, future prospective studies should focus in this particular patient population.
The current status of "Troitsk nu-mass" experiment in search for sterile neutrino
Creators: name: Abdurashitov, D. N.
name: Belesev, A. I.
name: Berlev, A. I.
name: Chernov, V. G.
name: Geraskin, E. V.
name: Golubev, A. A.
name: Koroteev, G. A.
name: Likhovid, N. A.
name: Lokhov, A. A.
name: Markin, A. I.
name: Nozik, A. A.
name: Pantuev, V. S.
name: Parfenov, V. I.
name: Skasyrskaya, A. K.
name: Titov, N. A.
name: Tkachev, I. I.
name: Tkachov, F. V.
name: Zadorozhny, S. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We propose a new experiment to search for a sterile neutrino in a few keV mass range at the "Troitsk nu-mass" facility. The expected signature corresponds to a kink in the electron energy spectrum in tritium beta-decay. The new goal compared to our previous experiment will be precision spectrum measurements well below end point. The experimental installation consists of a windowless gaseous tritium source and a high resolution electromagnetic spectrometer. We estimate that the current bounds on the sterile neutrino mixing parameter can be improved by an order of magnitude in the mass range under 5 keV without major upgrade of the existing equipment. Upgrades of calibration, data acquisition and high voltage systems will allow to improve the bounds by another order of magnitude.
description: 19 pages, 11 figures
Alcohol's harm to others in 2021: Who bears the burden?
Creators: name: Laslett, Anne-Marie
name: Room, Robin
name: Kuntsche, Sandra
name: Anderson-Luxford, Daniel
name: Willoughby, Breanna
name: Doran, C
name: Jenkinson, R
name: Smit, Koen
name: Egerton-Warburton, D
name: Jiang, Heng
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 5203
subject: Clinical and health psychology
classificationCode: 4206
subject: Public health

description: Background and aims: Alcohol's harm to others (AHTO) has become a key driver of national and international alcohol policy. This study aimed to produce a contemporary, comprehensive estimate of the correlates and harms from others' drinking in 2021 in Australia. Design, setting, participants and measurements: Across Australia, 2574 adults (1380 women; 1172 men) were sampled via two cross-sectional survey modes: a random-digit dial mobile phone sample of 1000 people and 1574 people from the Life in Australia™ panel survey. In 2021 participants were asked about harms they had experienced from the drinking of family, friends, co-workers and the public in the past year. Applying combined sample weights from each mode, bivariable and adjusted multivariable logistic regressions were used to analyse differences in rates of AHTO by participant gender, age, residence in rural or metropolitan regions, country of birth, education and employment. Findings: In 2021, 23.6% reported being negatively affected by strangers' drinking and 21.3% by the drinking of someone they knew, with 34.3% reporting being negatively affected a lot or a little by either; 42.4% of respondents reported specific harms from strangers' drinking. Thus, 48.1% of respondents reported any harm (negative effects or specific harms) from others' drinking. Women, younger people, Australian-born and heavier episodic drinkers reported significantly higher rates of AHTO compared with other respondents. Smaller percentages (7.5%) of participants reported being harmed substantially by others' drinking, including by people they knew (5.8%) or strangers (2.3%). Stratified analyses showed that heavier drinking, furloughed, younger men who were born overseas in English-speaking countries were affected by others' drinking, whereas women were affected regardless of these factors (apart from age). Conclusions: More than one-third of Australian adults appear to have been negatively affected by others' drinking in 2021, with women, younger people and heavier drinkers at greater risk. Substantial harm appears to be more likely to arise from the drinking of people Australians know than from strangers' drinking.
Additional file 2 of MetaLonDA: a flexible R package for identifying time intervals of differentially abundant features in metagenomic longitudinal studies
Creators: name: Metwally, Ahmed A.
name: Yang, Jie
name: Ascoli, Christian
name: Dai, Yang
name: Finn, Patricia W.
name: Perkins, David L.
Publisher: name: Figshare
Year: 2018
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: 60506 Virology

description: Zero-inflation probability distribution of the fitted ZIP distribution. Read counts are taken from the Caporaso et al., study. (PDF 3369 kb)
Which is the flavor of cosmic neutrinos seen by IceCube?
Creators: name: Palladino, A.
name: Pagliaroli, G.
name: Villante, F. L.
name: Vissani, F.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We analyze the high-energy neutrino events observed by IceCube, aiming to probe the initial flavor of cosmic neutrinos. We study the track-to-shower ratio of the subset with energy above 60 TeV, where the signal is expected to dominate and show that different production mechanisms give rise to different predictions even accounting for the uncertainties due to neutrino oscillations. We include for the first time the passing muons observed by IceCube in the analysis. They corroborate the hypotheses that cosmic neutrinos have been seen and their flavor matches expectations.
description: 4 pages, 1 figure
THE 'CYCLE OF DOING COERCION': AN ETHNOGRAPHY ON THE USE OF FORCE AND VIOLENCE IN BOTH A PRISON AND AN ASYLUM
Creators: name: GARIGLIO, LUIGI
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: This thesis firstly introduces the normative approach to power and Coercion on the landing selectively addressing the literatures of prison sociology, and policing . Then it presents the interactionist approach adopted. In the substantive part of the thesis it will outline the ?organization of the use-of-force in practice?. Chapter 5 focuses on what officers do when they routinely patrol the wing, either in calm and boring situations or during more violent situations that may or may not lead to the start of what is here called and reconstructed as the ?Cycle of doing coercion? (that I also call the? Cycle of the use-of-force and violence? or simply ?the Cycle?). Both Chapter 6 and 7 will instead focus on the emergency squad intervention on the wing. Lastly,Chapter 8 is methodologically oriented and deals selectively only with few relevant methodological and ethical issues that have emerged doing this particular ethnography in a custodila complex in Italy.
National Myth and Global Aesthetics: Reading Yeats alongside Chinese Poetic Modernism, pp. 210-234.
Creators: Lupke, Christopher
Publisher: name: University of Alberta Library
Year: 2019

One of the conundrums of modern Chinese literary studies is how to navigate the tortuous road between the particular cultural heritage from which it arises, the global phenomena of such trends as modernism, and the individual creative voice. Some adopt the strategy that indigenous cultures and westernization are mutually exclusive. Others emphasize the need to view Chinese modernism as part of a global trend in which cultural and national specificities are at best superficial, cosmetic, and incidental. In carrying out such discussions, scholars in the first camp tend to eschew comparative discussions of Chinese and Western authors. Scholars who are more internationalist in their approach embrace such comparisons. Underlying the overarching argument is the subtle, or sometimes not so subtle, attitude that those who readily adopt from the west are not authentically Chinese, and that those who tap their own tradition for creative inspiration must be antagonistic to modernism. In this essay, by providing discussions of William Butler Yeats, Wu Xinghua, Luo Fu, and Xiao Kaiyu, I advance the view that it is precisely the ability to mine the native landscape, transforming it into the rejuvenated imagery of a modern form, that makes contemporary Chinese poets modernist in style and outlook. By featuring Yeats, I suggest that it is not only Asian authors who bridle against the converging trends of modernization. Western poets such as Yeats, who in his lifetime saw himself as on the margin only to become a leading influence in global modernism, were participants in a pitched battle to maintain and resurrect the myths and narratives of their own nation. Yeats’s imagery is a rich amalgam of Biblical, classical, and local legend that is dialectically fused into disciplined, modern verse structure. Poems of Wu Xinghua such as “Xi Shi” bespeak the multilayered and multivalent sentiments of the modern author in China. Luo Fu’s long poem “Driftwood” is the most extended, and yet carefully wrought, example of the modern sensibility of exile in Chinese literature. Xiao Kaiyu's "On the Outskirts of Xi'an" is written like a modern "fu" rhapsody, a catalog of catastrophe. The picture that develops is one of complicated, even conflicted, feelings toward the modern predicament that are best articulated through a hybrid style that does not forswear their own past but is still receptive to the innovations as well as circumstances and conditions of a modern, global social milieu. Their situations were similar, their grievances shared, their thoughts resound with a dose of affinity, and they all possess a desire to express themselves in the somewhat controlled linguistic idiom of verse rather than a more expansive narrative mode. My goal is not to provide a taxonomy of national myth but to illustrate how echoes of Yeats work, preoccupations, and methods of resolving his troubles in writing have a modern kinship with contemporary Chinese poets.
On the Analytical Tractability of Hexagonal Network Model with Random User Location
Creators: name: Nasri, Ridha
name: Jaziri, Aymen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Explicit derivation of interferences in hexagonal wireless networks has been widely considered intractable and requires extensive computations with system level simulations. In this paper, we fundamentally tackle this problem and explicitly evaluate the downlink Interference-to-Signal Ratio (ISR) for any mobile location $m$ in a hexagonal wireless network, whether composed of omni-directional or tri-sectorized sites. The explicit formula of ISR is a very convergent series on $m$ and involves the use of Gauss hypergeometric and Hurwitz Riemann zeta functions. Besides, we establish simple identities that well approximate this convergent series and turn out quite useful compared to other approximations in literature. The derived expression of ISR is easily extended to any frequency reuse pattern. Moreover, it is also exploited in the derivation of an explicit form of SINR distribution for any arbitrary distribution of mobile user locations, reflecting the spatial traffic density in the network. Knowing explicitly about interferences and SINR distribution is very useful information in capacity and coverage planning of wireless cellular networks and particularly for macro-cells' layer that forms almost a regular point pattern.
Superconducting Detectors for Super Light Dark Matter
Creators: name: Hochberg, Yonit
name: Zhao, Yue
name: Zurek, Kathryn M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We propose and study a new class of superconducting detectors which are sensitive to O(meV) electron recoils from dark matter-electron scattering. Such devices could detect dark matter as light as the warm dark matter limit, mX > keV. We compute the rate of dark matter scattering off of free electrons in a (superconducting) metal, including the relevant Pauli blocking factors. We demonstrate that classes of dark matter consistent with terrestrial and cosmological/astrophysical constraints could be detected by such detectors with a moderate size exposure.
description: 6 pages, 2 figures; v2: improved detection discussion, modified benchmark model
Three-dimensional non-vacuum pulsar outer-gap model: Localized acceleration electric field in the higher altitudes
Creators: name: Hirotani, Kouichi
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We investigate the particle accelerator that arises in a rotating neutron-star magnetosphere. Solving the Poisson equation for the electro-static potential, the Boltzmann equations for relativistic electrons and positrons, and the radiative transfer equation simultaneously, we demonstrate that the electric field is substantially screened along the magnetic field lines by the pairs that are created and separated within the accelerator. As a result, the magnetic-field-aligned electric field is localized in the higher altitudes near the light cylinder and efficiently accelerates the positrons created in the lower altitudes outwards but not the electrons inwards. The resulting photon flux becomes predominantly outwards, leading to typical double-peak light curves, which are commonly observed from many high-energy pulsars.
description: 5 pages, 5 figures; Accepted for publication in ApJ Letters
Additional file 4: of Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study
Creators: name: Khie Lie
name: Chuen-Yen Lau
name: Nguyen Van Vinh Chau
name: T. West
name: Direk Limmathurotsakul
Publisher: name: Figshare
Year: 2018
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Table S3. Baseline characteristics and mortality by country. (DOCX 65Â kb)
Mono versus Dual Antiplatelet Therapy after Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis
Creators: name: Khalil, Charl
name: Mosleh, Wassim
name: Megaly, Michael
name: Sumeet Gandhi
name: Iskander, Fady H.
name: Iskander, Mina H.
name: Ibrahim, Amira
name: Tanvi Shah
name: Ekladios, Catherine
name: Corbelli, John
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Science Policy

description: Background: Dual antiplatelet therapy (DAPT) is routinely prescribed after transcatheter aortic valve replacement (TAVR) despite the lack of definitive data demonstrating its superiority over mono-antiplatelet therapy (MAPT). We aim to investigate the benefits of DAPT versus MAPT and at different follow-up time points post TAVR. Methods: A systematic search was conducted for studies investigating DAPT versus MAPT in patients who underwent TAVR. The primary outcome was net adverse clinical events (NACE) at longest reported follow-up, defined as a composite end-point of all-cause mortality, major stroke, myocardial infarction (MI), and combined life threatening and major bleeding. Secondary endpoints included each outcome individually. We performed subgroup analysis according to study type (randomized control trials vs. observational studies) and follow-up duration post-TAVR (≤ 30 days, between 3 and 6 months, and ≥ 1 year). Results: Twelve studies with 9,650 patients were included. Post-TAVR MAPT was associated with significantly reduced NACE (0.60 [0.45, 0.81], p p = 0.01), and combined life threatening and major bleeding (0.57 [0.39, 0.84], p = 0.005) in the first 30 days after the procedure when compared to DAPT. The difference in outcomes diminishes with longer-term follow up durations (3–6 month or ≥ 6-month). No differences were seen with other secondary endpoints. Conclusion: MAPT is associated with improved outcomes compared to DAPT in the first 30 days post-TAVR with no difference in outcomes on longer-term follow up. Future prospective, adequately powered, multicenter, placebo-controlled, randomized double-blinded cohort studies are warranted to confirm our findings.
$\ell_0$ Sparsifying Transform Learning with Efficient Optimal Updates and Convergence Guarantees
Creators: name: Ravishankar, Saiprasad
name: Bresler, Yoram
Publisher: name: arXiv
Year: 2015
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Many applications in signal processing benefit from the sparsity of signals in a certain transform domain or dictionary. Synthesis sparsifying dictionaries that are directly adapted to data have been popular in applications such as image denoising, inpainting, and medical image reconstruction. In this work, we focus instead on the sparsifying transform model, and study the learning of well-conditioned square sparsifying transforms. The proposed algorithms alternate between a $\ell_0$ "norm"-based sparse coding step, and a non-convex transform update step. We derive the exact analytical solution for each of these steps. The proposed solution for the transform update step achieves the global minimum in that step, and also provides speedups over iterative solutions involving conjugate gradients. We establish that our alternating algorithms are globally convergent to the set of local minimizers of the non-convex transform learning problems. In practice, the algorithms are insensitive to initialization. We present results illustrating the promising performance and significant speed-ups of transform learning over synthesis K-SVD in image denoising.
description: Accepted to IEEE Transactions on Signal Processing
Uncovering allosteric pathways in caspase-1 with Markov transient analysis and multiscale community detection
Creators: name: Amor, B.
name: Yaliraki, S. N.
name: Woscholski, R.
name: Barahona, M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Biomolecules (q-bio.BM)
subject: FOS: Biological sciences

description: Allosteric regulation at distant sites is central to many cellular processes. In particular, allosteric sites in proteins are a major target to increase the range and selectivity of new drugs, and there is a need for methods capable of identifying intra-molecular signalling pathways leading to allosteric effects. Here, we use an atomistic graph-theoretical approach that exploits Markov transients to extract such pathways and exemplify our results in an important allosteric protein, caspase-1. Firstly, we use Markov Stability community detection to perform a multiscale analysis of the structure of caspase-1 which reveals that the active conformation has a weaker, less compartmentalised large-scale structure as compared to the inactive conformation, resulting in greater intra-protein coherence and signal propagation. We also carry out a full computational point mutagenesis and identify that only a few residues are critical to such structural coherence. Secondly, we characterise explicitly the transients of random walks originating at the active site and predict the location of a known allosteric site in this protein quantifying the contribution of individual bonds to the communication pathway between the active and allosteric sites. Several of the bonds we find have been shown experimentally to be functionally critical, but we also predict a number of as yet unidentified bonds which may contribute to the pathway. Our approach offers a computationally inexpensive method for the identification of allosteric sites and communication pathways in proteins using a fully atomistic description.
description: 14 pages, 8 figures
Impact of Resting Heart Rate at 30 Days Following Transcatheter or Surgical Aortic Valve Replacement and Cardiovascular Outcomes: Insights from The PARTNER 2 Trial
Creators: name: Macedo, Leon G. R.
name: Kosmidou, Ioanna
name: Crowley, Aaron
name: Alu, Maria
name: Praz, Fabien
name: Chen, Shmuel
name: Nazif, Tamim
name: Babaliaros, Vasilis
name: Herrmann, Howard C.
name: Kapadia, Samir
name: Makkar, Raj
name: Webb, John
name: Thourani, Vinod H.
name: Leon, Martin B.
name: Susheel Kodali
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: 60506 Virology
subject: FOS: Biological sciences

description: Background: Elevated resting heart rate (RHR) is associated with adverse cardiovascular outcomes in patients with untreated aortic valve stenosis (AS). However, the impact of RHR following transcatheter (TAVR) or surgical aortic valve replacement (SAVR) on cardiovascular outcomes is unknown. We therefore sought to determine the effect of RHR at 30 days after aortic valve replacement (AVR) on 2-year outcomes in patients with severe symptomatic AS. Methods: The study population consists of 3170 patients from the PARTNER 2 Trial and its embedded registries who underwent TAVR or SAVR for severe AS, and had available 12-lead electrocardiograms demonstrating sinus rhythm at 30 days post-procedure. Outcomes at 2 years were analyzed according to 30-day RHR modeled as a continuous variable and in groups (RHR ≥75 bpm and RHR <75 bpm). Results: By multivariable analysis, RHR ≥75 bpm at 30 days after AVR was an independent predictor of the composite endpoint of all-cause death, rehospitalization or stroke (hazard ratio [HR] 1.26, 95% confidence interval [CI], 1.05–1.52, p = 0.015) and rehospitalization (HR 1.42, 95% CI, 1.12–1.79, p = 0.004). Similarly, RHR modeled as a continuous variable (per 5 bpm) remained an independent predictor of all-cause death, rehospitalization or stroke (adjusted HR 1.07, 95% CI, 1.03–1.11, p = 0.0007), and rehospitalization (adjusted HR 1.09, 95% CI, 1.04–1.14, p = 0.0003) at 2 years. Conclusions: In patients with severe AS treated with TAVR or SAVR, resting heart rate at 30 days post-procedure was an independent predictor of the composite endpoint of all-cause death, rehospitalization or any stroke, and of rehospitalization at 2 years.
Admittance of a long diffusive SNS junction
Creators: name: Tikhonov, K. S.
name: Feigel'man, M. V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The dynamical properties of hybrid normal metal/superconductor structures have recently come into research focus both experimentally and theoretically. Recent experimental studies of the coherent admittance $% Y(ω)$ of SNS rings as function of the phase difference $ϕ_{0}$ are still not fully understood. Here we concentrate on the linear response regime, calculating $Y(ω)$ by solving Usadel equations, linearised in electric field. Although partially reproducing previously known results, we find qualitatively different behaviour in the collisionless regime of $τ_{in}^{-1}\ll ω\lesssim E_{Th}$ and high temperature $T\gg E_{Th}$ and low temperature $T\lesssim E_{Th}$ near the minigap closing $ϕ_{0}\sim π$. We find that the dissipative part $\mbox{Re}Y(ω)$ peaks when the minigap closes (at a phase difference of $π$) even at high temperatures, when the equilibrium supercurrent is fully suppressed.
MPEC 2023-O97 : 2023 OU3
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 OU3

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Safety and Efficacy of Percutaneous Mitral Valve-in-Valve and Mitral Valve-in-Ring Procedures: Systematic Review and Pooled Analysis of 30 Day and One Year Outcomes
Creators: name: Prasanna Sengodan
name: Kesavan Sankaramangalam
name: Yash Jobanputra
name: Athappan, Ganesh
name: Jaber, Wael
name: White, Jonathon
name: Mick, Stephanie
name: Navia, Jose
name: Krishnaswamy, Amar
name: E. Murat Tuzcu
name: Kapadia, Samir
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: Science Policy
subject: 60506 Virology

description: Background: The purpose of this study was to perform a systematic review and pooled analysis to evaluate 30-day and 1-year outcomes of transcatheter mitral valve-in-valve (VIV) and valve-in-ring (VIR) procedures. Data from the Valve-in-Valve Data Registry revealed that there were several safety and efficacy concerns, although procedural success was achieved in most cases. Methods: Studies reporting data on either mitral VIV and/or VIR with at least five patients were pooled using weighted proportional analysis. Results: The 30-day pooled estimate of all-cause mortality in the mitral VIV group was 7%, valve embolization, 5%, stroke, 3%, and major bleeding, 9%. At 1 year the all-cause mortality was 11%, valve thrombosis, 10%, stroke, 6%, and major bleeding, 16%. In the mitral VIR group, the 30-day pooled estimate for all-cause mortality was 8%, renal failure, 11%, valve embolization, 3%, and left ventricular outflow tract obstruction, 10% and at 1 year the all-cause mortality was about 22%. Conclusions: Mitral VIV and VIR procedures are safe and feasible in high risk surgical candidates. The long-term safety and efficacy data beyond 1 year for both mitral VIV and VIR need to be established.
Comprehensive literature review of monkeypox
Creators: name: Hatmal, Ma’mon M.
name: Al-Hatamleh, Mohammad A. I.
name: Olaimat, Amin N.
name: Ahmad, Suhana
name: Hasan, Hanan
name: Suhaimi, Nurfatihah Azlyna Ahmad
name: Albakri, Khaled A.
name: Alzyoud, Anas Abedalbaset
name: Kadir, Ramlah
name: Mohamud, Rohimah
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: The current outbreak of monkeypox (MPX) infection has emerged as a global matter of concern in the last few months. MPX is a zoonosis caused by the MPX virus (MPXV), which is one of the Orthopoxvirus species. Thus, it is similar to smallpox caused by the variola virus, and smallpox vaccines and drugs have been shown to be protective against MPX. Although MPX is not a new disease and is rarely fatal, the current multi-country MPX outbreak is unusual because it is occurring in countries that are not endemic for MPXV. In this work, we reviewed the extensive literature available on MPXV to summarize the available data on the major biological, clinical and epidemiological aspects of the virus and the important scientific findings. This review may be helpful in raising awareness of MPXV transmission, symptoms and signs, prevention and protective measures. It may also be of interest as a basis for performance of studies to further understand MPXV, with the goal of combating the current outbreak and boosting healthcare services and hygiene practices. Trial registration:ClinicalTrials.gov identifier: NCT02977715.. Trial registration:ClinicalTrials.gov identifier: NCT03745131.. Trial registration:ClinicalTrials.gov identifier: NCT00728689.. Trial registration:ClinicalTrials.gov identifier: NCT02080767..
Standard and non-standard neutrino-nucleus reactions cross sections and event rates to neutrino detection experiments
Creators: name: Papoulias, D. K.
name: Kosmas, T. S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Open neutrino physics issues require precision studies, both theoretical and experimental ones, and towards this aim coherent neutral current neutrino-nucleus scattering events are expected to be observed soon. In this work, we explore $ν$-nucleus processes from a nuclear theory point of view and obtain results with high confidence level based on accurate nuclear structure cross sections calculations. Besides cross sections, the present study includes simulated signals expected to be recorded by nuclear detectors, differential event rates as well as total number of events predicted to be measured. Our original cross sections calculations are focused on measurable rates for the Standard Model process, but we also perform calculations for various channels of the non-standard neutrino-nucleus reactions and come out with promising results within the current upper limits of the corresponding exotic parameters. We concentrate on the possibility of detecting (i) supernova neutrinos by using massive detectors like those of the GERDA and SuperCDMS dark matter experiments and (ii) laboratory neutrinos produced near the spallation neutron source facilities (at Oak Ridge National Lab) by the COHERENT experiment. Our nuclear calculations take advantage of the relevant experimental sensitivity and employ the severe bounds extracted for the exotic parameters entering the Lagrangians of various particle physics models and specifically those resulting from the charged lepton flavour violating $μ^{-} \rightarrow e^{-}$ experiments (Mu2e and COMET experiments).
description: includes 3 tables, 9 figures, Article Ref.:Advances in High Energy Physics, Article ID 763648, in press
Embeddings models for Buddhist Sanskrit
Creators: name: Lugli, Ligeia
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 470404
subject: Corpus linguistics

description: Ligeia Lugli, Matej Martinc, Andraž Pelicon, and Senja Pollak. 2022. Embeddings models for Buddhist Sanskrit. In Proceedings of the Thirteenth Language Resources and Evaluation Conference, pages 3861–3871, Marseille, France. European Language Resources Association.
Supplementary Material One from Automated acoustic detection of the Geoffroy's spider monkey highlights tipping points of human disturbance
Creators: name: Lawson, Jenna
name: Rizos, George
name: Jasinghe, Dui
name: Whitworth, Andrew
name: Schuller, Björn
name: Banks-Leite, Cristina
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences

description: As more land is altered by human activity and more species become at risk of extinction, it is essential that we understand the requirements for conserving threatened species across human-modified landscapes. Owing to their rarity and often sparse distributions, threatened species can be difficult to study and efficient methods to sample them across wide temporal and spatial scales have been lacking. Passive acoustic monitoring (PAM) is increasingly recognized as an efficient method for collecting data on vocal species; however, the development of automated species detectors required to analyse large amounts of acoustic data is not keeping pace. Here, we collected 35 805 h of acoustic data across 341 sites in a region over 1000 km2 to show that PAM, together with a newly developed automated detector, is able to successfully detect the endangered Geoffroy's spider monkey (Ateles geoffroyi), allowing us to show that the Geoffroy's spider monkey was absent below a threshold of 80% forest cover and within 1 km of primary paved roads and occurred equally in old growth and secondary forests. We discuss how this methodology circumvents many of the existing issues in traditional sampling methods and can be highly successful in the study of vocally rare or threatened species. Our results provide tools and knowledge for setting targets and developing conservation strategies for the protection of the Geoffroy's spider monkey.
Temperature in the Throat
Creators: name: Kaviani, Dariush
name: Mosaffa, Amir Esmaeil
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the temperature of extended objects in string theory. Rotating probe D-branes admit horizons and temperatures a la Unruh effect. We find that the induced metrics on slow rotating probe D1-branes in holographic string solutions including warped Calabi-Yau throats have distinct thermal horizons with characteristic Hawking temperatures even if there is no black hole in the bulk Calabi-Yau. Taking the UV/IR limits of the solution, we show that the world volume black hole nucleation depends on the deformation and the warping of the throat. We find that world volume horizons and temperatures of expected features form not in the regular confining IR region but in the singular nonconfining UV solution. In the conformal limit of the UV, we find horizons and temperatures similar to those on rotating probes in the AdS throat found in the literature. In this case, we also find that activating a background gauge field form the U(1) R--symmetry modifies the induced metric with its temperature describing two different classes of black hole solutions.
description: Revised, extended and published version
Single Anti-Platelet Therapy versus Dual Anti-Platelet Therapy after Transcatheter Aortic Valve Replacement: A Meta-Analysis
Creators: name: Abuzaid, Ahmed
name: Ranjan, Pragya
name: DO, Carly Fabrizio
name: DO, Kevin Felpel
name: Raveen Chawla MD
name: Topic, Adrienne
name: Elgendy, Islam Y.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology

description: Background: The optimal anti-platelet regimen after transcatheter aortic valve replacement (TAVR) remains uncertain. The objective of this study was to compare the efficacy and safety of single anti-platelet therapy (SAPT) vs. dual anti-platelet therapy (DAPT) after transcatheter aortic valve replacement (TAVR). Methods: Electronic databases were searched for randomized and observational studies, which compared SAPT versus DAPT after TAVR. The primary outcomes were all-cause mortality, and major bleeding. Summary adjusted risk ratios (RR) were calculated using a Der-Simonian and Liard model. The risk of bias of the included studies was assessed by the Cochrane scale and New-castle Ottawa assessment tool. Results: A total of 10 studies with 2,412 patients were included. There was no difference in 30-days all-cause mortality (RR 1.19, 95% CI 0.79–1.81, p = 0.41, I 2 = 0.0%) and at the longest available follow up (i.e. mean 6.4 months) (RR 1.03, 95% CI 0.69–1.57, p = 0.86, I 2 = 0.0%). The risk of major bleeding was higher in the DAPT group (RR 2.14, 95% CI 1.37–3.31, p = 0.001). These findings were consistent on analyzing randomized versus observational studies (Pinteraction = 0.97, and 0.76 for all-cause mortality and major bleeding, respectively). There was no difference in the risk of life-threatening bleeding, major vascular complications, myocardial infarction, and stroke between both groups (all p-values > 0.05). Conclusion: DAPT post TAVR is associated with an increased risk of major bleeding with no benefit on mortality, stroke, or myocardial infarction. The evidence is driven mainly from observational studies, and therefore future high quality randomized trials are needed.
Comprehensive Literature Review of Monkeypox
Creators: name: Hatmal, Ma’mon M.
name: Al-Hatamleh, Mohammad A. I.
name: Olaimat, Amin N.
name: Ahmad, Suhana
name: Hasan, Hanan
name: Suhaimi, Nurfatihah Azlyna Ahmad
name: Albakri, Khaled A.
name: Abedalbaset, Anas
name: Kadir, Ramlah
name: Mohamud, Rohimah
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: The current outbreak of monkeypox (MPX) infection has emerged as a global matter of concern in the last few months. MPX is a zoonosis caused by the MPX virus (MPXV), which is one of the Orthopoxvirus species. Thus, it is similar to smallpox caused by the variola virus, and smallpox vaccines and drugs have been shown to be protective against MPX. Although MPX is not a new disease and is rarely fatal, the current multi-country MPX outbreak is unusual because it is occurring in countries that are not endemic for MPXV. In this work, we reviewed the extensive literature available on MPXV to summarize the available data on the major biological, clinical and epidemiological aspects of the virus and the important scientific findings. This review may be helpful in raising awareness of MPXV transmission, symptoms and signs, prevention and protective measures. It may also be of interest as a basis for performance of studies to further understand MPXV, with the goal of combating the current outbreak and boosting healthcare services and hygiene practices. Trial registration:ClinicalTrials.gov identifier: NCT02977715.. Trial registration:ClinicalTrials.gov identifier: NCT03745131.. Trial registration:ClinicalTrials.gov identifier: NCT00728689.. Trial registration:ClinicalTrials.gov identifier: NCT02080767..
Maximal Holevo quantity based on weak measurements
Creators: name: Wang, Yao-Kun
name: Fei, Shao-Ming
name: Wang, Zhi-Xi
name: Cao, Jun-Peng
name: Fan, Heng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Holevo bound is a keystone in many applications of quantum information theory. We propose "weak maximal Holevo quantity" with weak measurements as the generalization of the standard Holevo quantity which is defined as the optimal projective measurements. The scenarios that weak measurements is necessary are that only the weak measurements can be performed because for example the system is macroscopic or that one intentionally tries to do so such that the disturbance on the measured system can be controlled for example in quantum key distribution protocols. We evaluate systematically the weak maximal Holevo quantity for Bell-diagonal states and find a series of results. Furthermore, we find that weak measurements can be realized by noise and project measurements.
description: 29 pages,3 figures
TalkBank and CLARIN
Creators: name: Macwhinney, Brian
Publisher: name: Figshare
Year: 2018
Subjects: subject: 170204 Linguistic Processes (incl. Speech Production and Comprehension)
subject: FOS: Psychology

description: TalkBank promotes the use of corpora, web-based access, multimedia linkage, and human language
technology (HLT) for the study of spoken language interactions in a variety of discourse
types across many languages, involving children, second language learners, bilinguals, people
with language disorders, and classroom learners. Integration of these materials within CLARIN
provides open access to access a large amount of research data, as well as a test bed for the development
of new computational methods
Chalcura upeensis Fullaway
Creators: name: Swezey, O. H.
Publisher: name: Zenodo
Year: 1946
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Eucharidae
Chalcura
Chalcura upeensis

description: 9.Chalcura upeensis Fullaway, Haw. Ent. Soc., Proc. 2: 285, 1913. An ant parasite, described by Fullaway from a single male specimen. Two specimens, Upi Trail, May 5, in the same district where it was collected by Fullaway in 1911. Two specimens, one retained in U. S. National Museum.
description: Published as part of Swezey, O. H., 1946, Notes On Some Guam Chalcidoidea, pp. 211-219 in Insects of Guam II, Honolulu, Hawaii :Bernice P. Bishop Museum on page 212, DOI: 10.5281/zenodo.5173516