cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Essays in International Trade
Creators: name: Zhong, Jiatong
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Other economics not elsewhere classified

description: The first chapter quantitatively examines the impact of exporting countries' reputations for product quality on aggregate trade flows. I introduce a novel data set in which recall incidences retrieved from the Consumer Product Safety Commission are matched to U.S. import data from 1990-2009. Using a model of learning I construct a measure for exporter reputation where consumers internalize product recalls as bad signals. Structural estimation of the model finds that reputation is important and especially impactful for products used by children. The market share elasticity of exporter's reputation is around 1.49 across products, similar in magnitude to the average price elasticity, which is around 1.51. Improving reputation can increase export value, but reputation is sluggish: increasing reputation by 10\% can take decades for most exporters. Counterfactual exercises confirm that quality inspection institutions are welfare improving, and quality inspection is especially important for consumers of toys. The second chapter summarizes the correlation between export decisions of Chinese firms and product recalls for Chinese products. I use a new data set where I link recall data scraped from CPSC to monthly Chinese Customs Data. I found that recalls from previous months correlates negatively with the decision of export participation, but not with export value.
 The third chapter, coauthored with Kendall Kennedy and Xuan Jiang, analyzes how China's industrialization and the immediate export growth due to the Open Door Policy change Chinese teenagers' education decisions, which explains the education decline. We find that, middle school completion rates increased and high school completion rates decreased in response to export growth. This suggests a tradeoff between education and labor market opportunities in China. These education effects are more prominent for cohorts who were younger when China's Open Door Policy began, even though these teenagers also faced a stronger education system compared to the earlier cohorts.
sj-pdf-1-jht-10.1177_10963480211030319 – Supplemental material for Immersive Digital Tourism: The Role of Multisensory Cues in Digital Museum Experiences
Creators: name: Guo, Kexin
name: Fan, Alei
name: Lehto, Xinran
name: Day, Jonathon
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-pdf-1-jht-10.1177_10963480211030319 for Immersive Digital Tourism: The Role of Multisensory Cues in Digital Museum Experiences by Kexin Guo, Alei Fan, Xinran Lehto and Jonathon Day in Journal of Hospitality & Tourism Research
Additional file 1 of Molecular characterization of Glaesserella parasuis strains circulating in North American swine production systems
Creators: name: Mugabi, Robert
name: Silva, Ana Paula S. Poeta
name: Hu, Xiao
name: Gottschalk, Marcelo
name: Aragon, Virginia
name: Macedo, Nubia R.
name: Sahin, Orhan
name: Harms, Perry
name: Main, Rodger
name: Tucker, Alexander W.
name: Li, Ganwu
name: Clavijo, Maria J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1.
Additional file 1 of Environmental tobacco smoke exposure exaggerates bleomycin-induced collagen overexpression during pulmonary fibrogenesis
Creators: name: Wang, Qixin
name: Goracci, Chiara
name: Sundar, Isaac Kirubakaran
name: Rahman, Irfan
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1.
sj-docx-1-jet-10.1177_15266028211030536 – Supplemental material for First-in-Human Clinical Application of the Medyria TrackCath System in Endovascular Repair of Complex Aortic Aneurysms (ACCESS Trial): A Prospective Multicenter Single-Arm Clinical Trial
Creators: name: Floros, Nikolaos
name: Kölbel, Tilo
name: Tsilimparis, Nikolaos
name: Oberhuber, Alexander
name: Kindl, Daniel
name: Kalder, Johannes
name: Kotelis, Drosos
name: Schmidt, Andrej
name: Branzan, Daniela
name: Adolf, Daniela
name: Schelzig, Hubert
name: Wagenhäuser, Markus Udo
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Cardiology
subject: Medicine
subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-1-jet-10.1177_15266028211030536 for First-in-Human Clinical Application of the Medyria TrackCath System in Endovascular Repair of Complex Aortic Aneurysms (ACCESS Trial): A Prospective Multicenter Single-Arm Clinical Trial by Nikolaos Floros, Tilo Kölbel, Nikolaos Tsilimparis, Alexander Oberhuber, Daniel Kindl, Johannes Kalder, Drosos Kotelis, Andrej Schmidt, Daniela Branzan, Daniela Adolf, Hubert Schelzig and Markus Udo Wagenhäuser in Journal of Endovascular Therapy
Understanding Miocene Climatic Warmth
Creators: name: Dicks, Ashley J
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Climatology
Cloud physics
Atmospheric aerosols
Atmospheric sciences not elsewhere classified
Atmospheric dynamics

description: The mid-Miocene Climatic Optimum (MMCO), 17-14.50 million years ago, is studied using general circulation models (GCMs). This period of time is characterized by enhanced warming in the deep ocean and in the mid-to-high latitudes. Previous GCMs fail to accurately represent the warmer climate of the MMCO, providing evidence that other warming feedbacks are missing in the models. This study focuses on cloud feedbacks by modifying the Community Earth System Model (CESM 1.0) to explore the MMCO climate. We implement modifications in pre-industrial (284.7 ppm CO2) and modern slab ocean cases (367.0 ppm CO2, 400 ppm CO2, and 800 ppm CO2). One modified case showing the most potential implements an aerosol de- pendent ice nucleation mechanism and a theory based cloud phase separation. This modified case allows the model predicted aerosol concentrations to interact with the cloud microphysics and provide more realistic cloud water contents. The data shows an increase in surface temperature and increase in upper atmospheric cloud fraction when compared to the control case. Preliminary results suggest that this model is able to capture the mid-to-high latitude warming trends and weaker equator to pole temperature gradient.
TRUST ESTIMATION OF REAL-TIME SOCIAL HARM EVENTS
Creators: name: Pandey, Saurabh Pramod
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Applied computing not elsewhere classified
Software engineering not elsewhere classified
Digital processor architectures
System and network security
Distributed computing and systems software not elsewhere classified
Social and community informatics

description: Social harm involves incidents resulting in physical, financial, and emotional hardships such as crime, drug overdoses and abuses, traffic accidents, and suicides. These incidents require various law-enforcement and emergency responding agencies to coordinate together for mitigating their impact on the society. With the advent of advanced networking and computing technologies together with data analytics, law-enforcement agencies and people in the community can work together to proactively reduce social harm. With the aim of effectively mitigating social harm events in communities, this thesis introduces a distributed web application, Community Data Analytic for Social Harm (CDASH). CDASH helps in collecting social harm data from heterogenous sources, analyzing the data for predicting social harm risks in the form of geographic hotspots and conveying the risks to law-enforcement agencies. Since various stakeholders including the police, community organizations and citizens can interact with CDASH, a need for a trust framework arises, to avoid fraudulent or mislabeled incidents from misleading CDASH. The enhanced system, called Trusted-CDASH (T-CDASH), superimposes a trust estimation framework on top of CDASH. This thesis discusses the importance and necessity of associating a degree of trust with each social harm incident reported to T-CDASH. It also describes the trust framework with different trust models that can be incorporated for assigning trust while examining their impact on prediction accuracy of future social harm events. The trust models are empirically validated by running simulations on historical social harm data of Indianapolis metro area.
Additional file 2 of Molecular characterization of Glaesserella parasuis strains circulating in North American swine production systems
Creators: name: Mugabi, Robert
name: Silva, Ana Paula S. Poeta
name: Hu, Xiao
name: Gottschalk, Marcelo
name: Aragon, Virginia
name: Macedo, Nubia R.
name: Sahin, Orhan
name: Harms, Perry
name: Main, Rodger
name: Tucker, Alexander W.
name: Li, Ganwu
name: Clavijo, Maria J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 2.
Heat Generation Mechanisms in Energetic Composite Materials Under Ultrasonic Excitation
Creators: name: Roberts, Zane A
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Thermal dissipation of mechanical energy from periodic loading in energetic materials (EMs) leads to the creation of areas of intense, localized heating, called hot spots. The impact and shock conditions for the hot spot initiation of solid explosives have been extensively explored, but little work has focused on high-frequency contact loading. In order to design formulations to address unintentional initiation by mitigating heating in polymer-bonded explosives (PBXs) and other heterogeneous EMs, the mechanisms of heat generation which lead to the thermal initiation of energetic composites under ultrasonic excitation were explored. Heat generation mechanisms which may lead to unintentional initiation were identified through the diagnostic techniques of second harmonic generation (SHG) of δ-HMX (1,3,5,7-tetranitro-1,3,5,7-tetrazocine) crystals; X-ray phase contrast imaging (PCI) performed at the Argonne National Laboratory Advanced Photon Source; infrared (IR) thermography; and optical microscopy. This work concludes with high-speed mesoscale observations of dense layers of PETN (pentaerythritol tetraniterate), CL-20 (hexanitrohexaazaisowurtzitane), RDX (1,3,5-trinitro-1,3,5-triazine), and HMX which were damaged or driven to decomposition under acoustic insult using the non-intrusive imaging technique of shadowgraphy to detect hot spots within the transparent binder. Recommendations are formed which address binder adhesion, energetic material properties, and particle morphology on the vibration sensitivity of a PBX formulation.
sj-pdf-1-lrt-10.1177_14771535211026322 – Supplemental Material for A method to measure the spectral responsivity of a photometer using optical excitations with arbitrary spectral distributions
Creators: name: Martinsons, Christophe
name: Hlayhel, Raed
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental Material, sj-pdf-1-lrt-10.1177_14771535211026322 for A method to measure the spectral responsivity of a photometer using optical excitations with arbitrary spectral distributions by Christophe Martinsons and Raed Hlayhel in Lighting Research & Technology
STI tests and proportion of positive tests in female sex workers attending local public health departments in Germany in 2010/11
Creators: name: Bremer, Viviane
name: Haar, Karin
name: Gassowski, Martyna
name: Hamouda, Osamah
name: Nielsen, Stine
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2016
Subjects: subject: HIV
subject: Sex workers
subject: sexually transmitted diseases
subject: Community health service
subject: 610 Medizin

description: Background: In Germany, local public health departments (LPHD) are required to offer low-threshold access to confidential counselling and testing for sexually transmitted infections (STI) for sex workers. We collected data from LPHD in Germany to estimate the number of performed STI tests and the proportion of positive STI tests among attending female sex workers (FSW) in order to formulate recommendations for improving STI testing and care for FSW in Germany. Methods: We recruited LPHD across Germany to collect aggregated data on attending FSW between January 2010 and March 2011. Baseline characteristics, the number of attending FSW, STI tests (HIV, Chlamydia trachomatis, Neisseria gonorrhoea, syphilis and Trichomonas vaginalis) and the number of positive results were provided by participating LPHD. We described the number of STI tests per FSW visit and the proportion of positive test results, including interquartile range (IQR). We tested whether baseline characteristics of LPHD were associated with the proportion of positive test results. Results: Overall, 28 LPHD from 14 of the 16 federal states reported 9284 FSW visits over the study period, with a median of 188 FSW visits (IQR 45–440) per LPHD. Overall, a median of 77.1% (IQR 60.7–88.0) of visiting FSW received a test for Neisseria gonorrhoea, followed by HIV (66.0%, IQR 47.9–86.8), Chlamydia trachomatis (65.4%, IQR 50.7–83.6) and syphilis (61.6, IQR 48.6–78.6). In total, 22,914 STI tests were performed. The proportion of positive tests was 3.1% (IQR 1.3–4.8), with the highest proportion of positive tests for Chlamydia trachomatis (6.8%, IQR 2.5–10.4), followed by Neisseria gonorrhoea (3.2%, IQR 0.0–5.3), Trichomonas vaginalis (3.0%, IQR 0.0–15.4), syphilis (1.1%, IQR 0.0–1.3) and HIV (0.2%, IQR 0.0–0.4). The proportion of positive tests varied between 0 and 13.9% between LPHD, with a higher variation of proportion of positive tests in LPHD with a smaller number of reported STI tests. Conclusions: Participating LPHD varied in terms of performed STI tests and FSW visits. The proportion of positive STI tests was low, but varied between LPHD. This variation likely reflects different testing strategies. Existing testing guidelines should be used by all LPHD to ensure high quality care for FSW.
CD4-cell counts and presence of AIDS in HIV-positive patients entering specialized care—a comparison of migrant groups in the German ClinSurv HIV Cohort Study, 1999–2013
Creators: name: Zeitlmann, Nadine
name: Gunsenheimer-Bartmeyer, Barbara
name: Santos-Hövener, Claudia
name: Kollan, Christian
name: Heiden, Matthias An Der
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2016
Subjects: subject: Germany
subject: HIV
subject: AIDS
subject: Sub-Saharan Africa
subject: Care
subject: Migrants
subject: CD4
subject: South-East Asia
subject: Late presentation
subject: 610 Medizin

description: Background: Although early presentation to HIV-care is essential to ensure timely initiation of antiretroviral therapy, recent studies have shown that especially migrants present to HIV-care at a later stage of HIV-infection. Currently, thirty percent of all newly diagnosed HIV cases in Germany originate from abroad. So far it is unknown, which specific migrant groups in Germany are particularly at risk for late presentation to HIV-care. Methods: We used data from the Clinical Surveillance of HIV Disease (ClinSurv) cohort, a multi-centre observational cohort (01/01/1999 and 31/07/2013) and included treatment-naïve patients with valid information on country of origin and date of enrolment. Migrants were patients with country of origin outside Germany. We compared time trends for percentage of AIDS (CDC Stage C) and mean CD4-count at enrolment between migrants from Western Europe (WE), Central Europe (CE), Eastern Europe (EE), Sub-Saharan Africa (SSA), South East Asia (SEA) and non-migrants using multivariable regressions. Male non-migrants with mean age of 38-years constituted the reference group. Results: In total, 10,211 patients fulfilled the inclusion criteria, of which 2784 were migrants (SSA: 42%, CE: 17%, WE: 11%, EE: 10%, SEA: 9%). The percentage of patients with AIDS at enrolment was higher in SSA (Odds Ratio (OR)SSA: 1.44, 95%-confidence interval (95%-CI):1.12–1.84) and SEA-migrants (ORSEA:2.16, 95%-CI:1.43–3.27). In addition, female SEA-migrants, were more likely to present with AIDS than their male counterparts (OR:2.22, 95%-CI:1.18–4.17). Mean CD4-count at enrolment was lower for SSA- (Mean CD4-count ratio (IRR):0.72; 95%-CI:0.64-0.82) and SEA-migrants (IRR:0.62, 95%-CI:0.49-0.78). Over time, it increased in non-migrants and CE-migrants (by 1 and 3%/year, respectively), whereas no increase was seen for SEA and SSA. Conclusions: SSA and SEA-migrants in Germany present to HIV-care at a later stage of HIV infection than non-migrants. Additionally, previous research found a higher risk for late HIV-testing for migrants. Collecting information about the arrival date of migrants in Germany in the HIV notification system would help to understand to which extent these problems could be tackled in Germany. Moreover, participatory approaches for HIV-testing and care as well as research regarding knowledge, behaviour and attitudes towards these topics for SSA and SEA migrants should be expanded.
Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model
Creators: name: Fuhrmann, Franziska
name: Lischke, Timo
name: Gross, Fridolin
name: Scheel, Tobias
name: Bauer, Laura
name: Kalim, Khalid Wasim
name: Radbruch, Andreas
name: Herzel, Hanspeter
name: Hutloff, Andreas
name: Baumgrass, Ria
Publisher: name: Robert Koch-Institut
Year: 2016
Subjects: subject: 610 Medizin

description: The IL-2/IL-2Ralpha (CD25) axis is of central importance for the interplay of effector and regulatory T cells. Nevertheless, the question how different antigen loads are translated into appropriate IL-2 production to ensure adequate responses against pathogens remains largely unexplored. Here we find that at single cell level, IL-2 is binary (digital) and CD25 is graded expressed whereas at population level both parameters show graded expression correlating with the antigen amount. Combining in vivo data with a mathematical model we demonstrate that only this binary IL-2 expression ensures a wide linear antigen response range for Teff and Treg cells under real spatiotemporal conditions. Furthermore, at low antigen concentrations binary IL-2 expression safeguards by its spatial distribution selective STAT5 activation only of closely adjacent Treg cells regardless of their antigen specificity. These data show that the mode of IL-2 secretion is critical to tailor the adaptive immune response to the antigen amount.
CHLORAMINATION OF POLYAMIDE-BASED REVERSE OSMOSIS MEMBRANES IN THE PRESENCE OF HALIDES
Creators: name: Haflich, Holly M
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Environmental engineering not elsewhere classified

description: Polyamide based reverse osmosis (PA-RO) membranes are applied for the desalination of halide-containing waters such as seawater and brackish groundwater. They are the industry standard because of their high selectivity and ability to withstand a wide range of pH. However, one of their pitfalls is their propensity to undergo biofouling, which is deterioration due to biological growth. Biofouling is known to dramatically decrease membrane performance and increase energy consumption. In order to overcome biofouling, a disinfectant, typically free chlorine, is applied; however, free chlorine is known to react with the polyamide layer and result in further membrane deterioration and performance loss.
One topic that has garnered less attention is the application of chloramines and their interactions with the PA-RO membrane when applied as a biofouling control. Furthermore, the role of halides (e.g. chloride, bromide, and iodide) in the presence of chloramines must be further explored because they are known to react to form secondary species which are reactive toward PA-RO membranes. In Chapter 2, the PA based monomers benzanilide (BA) and N-Methyl-N-phenylbenzamide (N-CH3-BA) were used to model the PA layer. Monomers were exposed to halide containing waters and chloraminated with pre-formed NH2Cl over a wide range of pH. The decay and by-product formation after exposure were evaluated using HPLC-DAD, LC/MS, and/or GC/MS. Results indicated that pH of the system and bromide concentration controlled parent compound decay and brominated by-product formation, where low pH and high bromide concentrations led to the highest formation of brominated by-products.In Chapter 3, commercially made PA-RO membranes (SWC4-LD) were chloraminated or chlorinated with and without halides over a wide pH range. Their performance was evaluated after exposure through flux experiments using a dead-end flow cell. Results indicated that exposure to free chlorine led to the greatest change in flux and monochloramine resulted in the smallest change in flux. During chloramination of the membranes, the reactors containing bromide led to further change in flux than the chloramine only conditions. This was likely due to formation of secondary species that were reactive toward the PA membrane. Furthermore, Chapter 4 summarizes overall research contributions from this work and proposes future work pertaining to this topic.
Additional file 1 of Thai novice nurses’ lived experiences and perspectives of breastfeeding and human milk in the Neonatal Intensive Care Unit (NICU)
Creators: name: Srichalerm, Tippawan
name: Jacelon, Cynthia S.
name: Sibeko, Lindiwe
name: Granger, Jumpee
name: Briere, Carrie-Ellen
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1 Additional file 1: The semi–structured interview guide
Additional file 2 of Thai novice nurses’ lived experiences and perspectives of breastfeeding and human milk in the Neonatal Intensive Care Unit (NICU)
Creators: name: Srichalerm, Tippawan
name: Jacelon, Cynthia S.
name: Sibeko, Lindiwe
name: Granger, Jumpee
name: Briere, Carrie-Ellen
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 2 Additional file 2: The demographic characteristics of participants
Ongoing outbreaks of hepatitis A among men who have sex with men (MSM), Berlin, November 2016 to January 2017 – linked to other German cities and European countries
Creators: name: Werber, Dirk
name: Michaelis, Kai
name: Hausner, M.
name: Sissolak, D.
name: Wenzel, J.
name: Bitzegeio, J.
name: Belting, A.
name: Sagebiel, Daniel
name: Faber, Mirko
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Since 14 November 2016, 38 cases of hepatitis A have been notified in Berlin; of these, 37 were male and 30 reported to have sex with men (MSM). Median age of MSM cases is 31 years (range: 24–52 years). Phylogenetic analysis revealed three distinct sequences, linking cases in Berlin to those in other German cities and to clusters recognised in other European countries in 2016.
sj-pdf-1-imr-10.1177_03000605211014989 - Supplemental material for Nelfinavir restricts A549 cell growth by inhibiting STAT3 signaling
Creators: name: He, Fangli
name: Wang, Gang
name: Xu, ZhengQing
name: Huang, Zhihui
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Dentistry not elsewhere classified
subject: Emergency Medicine
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Nursing not elsewhere classified
subject: Nutrition and Dietetics not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Orthopaedics
subject: Sports Medicine
subject: Otorhinolaryngology
subject: Aged Health Care
subject: Paediatrics
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Public Health and Health Services not elsewhere classified
subject: Respiratory Diseases
subject: Sociological Methodology and Research Methods
subject: Surgery

description: Supplemental material, sj-pdf-1-imr-10.1177_03000605211014989 for Nelfinavir restricts A549 cell growth by inhibiting STAT3 signaling by Fangli He, Gang Wang, ZhengQing Xu and Zhihui Huang in Journal of International Medical Research
Evidence for Contemporary Switching of the O-Antigen Gene Cluster between Shiga Toxin-Producing Escherichia coli Strains Colonizing Cattle
Creators: name: Geue, Lutz
name: Menge, Christian
name: Eichhorn, Inga
name: Semmler, Torsten
name: Wieler, Lothar H.
name: Pickard, Derek
name: Berens, Christian
name: Barth, Stefanie A.
Publisher: name: Robert Koch-Institut
Year: 2017
Subjects: subject: STEC
subject: recombination
subject: E. coli
subject: O-antigen gene cluster
subject: genome sequencing
subject: 610 Medizin

description: Shiga toxin-producing Escherichia coli (STEC) comprise a group of zoonotic enteric pathogens with ruminants, especially cattle, as the main reservoir. O-antigens are instrumental for host colonization and bacterial niche adaptation. They are highly immunogenic and, therefore, targeted by the adaptive immune system. The O-antigen is one of the most diverse bacterial cell constituents and variation not only exists between different bacterial species, but also between individual isolates/strains within a single species. We recently identified STEC persistently infecting cattle and belonging to the different serotypes O156:H25 (n = 21) and O182:H25 (n = 15) that were of the MLST sequence types ST300 or ST688. These STs differ by a single nucleotide in purA only. Fitness-, virulence-associated genome regions, and CRISPR/CAS (clustered regularly interspaced short palindromic repeats/CRISPR associated sequence) arrays of these STEC O156:H25 and O182:H25 isolates were highly similar, and identical genomic integration sites for the stx converting bacteriophages and the core LEE, identical Shiga toxin converting bacteriophage genes for stx1a, identical complete LEE loci, and identical sets of chemotaxis and flagellar genes were identified. In contrast to this genomic similarity, the nucleotide sequences of the O-antigen gene cluster (O-AGC) regions between galF and gnd and very few flanking genes differed fundamentally and were specific for the respective serotype. Sporadic aEPEC O156:H8 isolates (n = 5) were isolated in temporal and spatial proximity. While the O-AGC and the corresponding 5′ and 3′ flanking regions of these aEPEC isolates were identical to the respective region in the STEC O156:H25 isolates, the core genome, the virulence associated genome regions and the CRISPR/CAS elements differed profoundly. Our cumulative epidemiological and molecular data suggests a recent switch of the O-AGC between isolates with O156:H8 strains having served as DNA donors. Such O-antigen switches can affect the evaluation of a strain's pathogenic and virulence potential, suggesting that NGS methods might lead to a more reliable risk assessment.
sj-docx-1-chl-10.1177_17475198211032835 – Supplemental material for Synthesis and properties of unsymmetrical porphyrins possessing an isonicotinic acid moiety and phenyl, methoxyphenyl, or chlorophenyl groups
Creators: name: Wang, Shiqi
name: Li, Yao
name: Wang, Binbin
Publisher: name: SAGE Journals
Year: 2021
Subjects: Materials Engineering not elsewhere classified

description: Supplemental material, sj-docx-1-chl-10.1177_17475198211032835 for Synthesis and properties of unsymmetrical porphyrins possessing an isonicotinic acid moiety and phenyl, methoxyphenyl, or chlorophenyl groups by Shiqi Wang, Yao Li and Binbin Wang in Journal of Chemical Research
Contact investigation after a fatal case of extensively drug-resistant tuberculosis (XDR-TB) in an aircraft, Germany, July 2013
Creators: name: Heiden, Maria An Der
name: Hauer, Barbara
name: Fiebig, Lena
name: Glaser-Paschke, Gisela
name: Stemmler, M.
name: Simon, C.
name: Rüsch-Gerdes, Sabine
name: Gilsdorf, Andreas
name: Haas, Walter
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: In July 2013, a passenger died of infectious extensively drug-resistant tuberculosis (XDR-TB) on board of an aircraft after a 3-hour flight from Turkey to Germany. Initial information indicated the patient had moved about the aircraft coughing blood. We thus aimed to contact and inform all persons exposed within the aircraft and to test them for newly acquired TB infection. Two-stage testing within 8 weeks from exposure and at least 8 weeks after exposure was suggested, using either interferon gamma release assays (IGRAs) or tuberculin skin test (TST). The TST cut-off was defined at a diameter > 10 mm; for differentiation between conversion and boosting, conversion was defined as increase of skin induration > 5 mm. Overall, 155 passengers and seven crew members were included in the investigation: the questionnaire response rate was 83%; 112 (69%) persons were tested at least once for TB infection. In one passenger, who sat next to the area where the patient died, a test conversion was registered. As of March 2017, no secondary active TB cases have been reported. We describe an unusual situation in which we applied contact tracing beyond existing European guidelines; we found one latent tuberculosis infection in a passenger, which we consider probably newly acquired.
sj-docx-1-pih-10.1177_09544119211031052 – Supplemental material for Biomechanical evaluation of an intramedullary clavicle screw in simple oblique and butterfly wedge fractures
Creators: name: Kunkle, Bryce F
name: DesJardins, John D
name: Campbell, Joel R
name: Eichinger, Josef K
name: Kissenberth, Michael J
name: Shaw, Kenneth A
name: Tokish, John M
name: Parada, Stephen A
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine
subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-docx-1-pih-10.1177_09544119211031052 for Biomechanical evaluation of an intramedullary clavicle screw in simple oblique and butterfly wedge fractures by Bryce F Kunkle, John D DesJardins, Joel R Campbell, Josef K Eichinger, Michael J Kissenberth, Kenneth A Shaw, John M Tokish and Stephen A Parada in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Ebola management centre proximity associated with reduced delays of healthcare of Ebola Virus Disease (EVD) patients, Tonkolili, Sierra Leone, 2014–15
Creators: name: Theocharopoulos, Georgios
name: Danis, Kostas
name: Greig, Jane
name: Hoffmann, Alexandra
name: Valk, Henriette De
name: Jimissa, Augustine
name: Tejan, Sumaila
name: Sankoh, Mohammed
name: Kleijer, Karline
name: Turner, Will
name: Achar, Jay
name: Duncombe, Jennifer
name: Lokuge, Kamalini
name: Gayton, Ivan
name: Broeder, Rob
name: Kremer, Ronald
name: Caleo, Grazia
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Between August-December 2014, Ebola Virus Disease (EVD) patients from Tonkolili District were referred for care to two Médecins Sans Frontières (MSF) Ebola Management Centres (EMCs) outside the district (distant EMCs). In December 2014, MSF opened an EMC in Tonkolili District (district EMC). We examined the effect of opening a district-based EMC on time to admission and number of suspect cases dead on arrival (DOA), and identified factors associated with fatality in EVD patients, residents in Tonkolili District. Residents of Tonkolili district who presented between 12 September 2014 and 23 February 2015 to the district EMC and the two distant EMCs were identified from EMC line-lists. EVD cases were confirmed by a positive Ebola PCR test. We calculated time to admission since the onset of symptoms, case-fatality and adjusted Risk Ratios (aRR) using Binomial regression. Of 249 confirmed Ebola cases, 206 (83%) were admitted to the distant EMCs and 43 (17%) to the district EMC. Of them 110 (45%) have died. Confirmed cases dead on arrival (n = 10) were observed only in the distant EMCs. The median time from symptom onset to admission was 6 days (IQR 4,8) in distant EMCs and 3 days (IQR 2,7) in the district EMC (p3 days after symptom onset) in the distant compared with the district EMC, but were less likely (aRR = 0.8; 95%CI 0.6–1.0) to have a high viral load (cycle threshold ≤22). A fatal outcome was associated with a high viral load (aRR 2.6; 95%CI 1.8–3.6) and vomiting at first presentation (aRR 1.4; 95%CI 1.0–2.0). The opening of a district EMC was associated with earlier admission of cases to appropriate care facilities, an essential component of reducing EVD transmission. High viral load and vomiting at admission predicted fatality. Healthcare providers should consider the location of EMCs to ensure equitable access during Ebola outbreaks.
Additional file 1 of Knowledge, protective behaviours, and perception of Lyme disease in an area of emerging risk: results from a cross-sectional survey of adults in Ottawa, Ontario
Creators: name: Logan, James J.
name: Sawada, Michael
name: Knudby, Anders
name: Ramsay, Tim
name: Blanford, Justine I.
name: Ogden, Nicholas H.
name: Kulkarni, Manisha A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Longitudinal change in health-related quality of life in people with prevalent and incident type 2 diabetes compared to diabetes-free controls
Creators: name: Schunk, Michaela
name: Reitmeir, Peter
name: Rückert-Eheberg, Ina-Maria
name: Tamayo, Teresa
name: Schipf, Sabine
name: Meisinger, Christa
name: Peters, Annette
name: Scheidt-Nave, Christa
name: Ellert, Ute
name: Hartwig, Saskia
name: Kluttig, Alexander
name: Völzke, Henry
name: Holle, Rolf
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: 610 Medizin

description: Objective: The objective of this analysis is to compare people with prevalent type 2 diabetes, incident type 2 diabetes and without diabetes with respect to longitudinal change in health-related quality of life (HRQOL) when adjusting for baseline determinants of HRQOL. Research design and methods: Primary baseline and follow-up data from three regional and one national population-based cohort studies in Germany were pooled for analysis. HRQOL was measured using physical and mental health summary scores (PCS and MCS) from the German version of the Short Form Health Survey with 36 or 12 items. Mean score change per observation year was compared between the three groups (prevalent diabetes, incident diabetes, no diabetes) based on linear regression models. Results: The analysis included pooled data from 5367 people aged 45–74 years at baseline. Of these, 85.5% reported no diabetes at baseline and follow-up, 6.3% reported diabetes at both baseline and follow-up (prevalent diabetes), and 8.2% reported diabetes only at follow-up (incident diabetes). Over a mean observation period of 8.7 years, annual decline in HRQOL scores is pronounced at 0.27–0.32 (PCS) and 0.34–0.38 (MCS) in the group with prevalent diabetes compared with people without diabetes. Those with incident diabetes showed intermediate values but did not differ significantly from people without diabetes after adjustment for covariates in the full model. Conclusion: Compared with data from cross-sectional analysis, the HRQOL loss associated with prevalent diabetes appears to be much larger than previously assumed.
Todesfälle durch Influenzapandemien in Deutschland 1918 bis 2009
Creators: name: Buchholz, Udo
name: Buda, Silke
name: Reuß, Annicka
name: Haas, Walter
name: Uphoff, Helmut
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2016
Subjects: subject: Influenza
subject: Grippe
subject: Mortalität
subject: Pandemie
subject: Exzess-Mortalitäts-Schätzung
subject: 610 Medizin

description: Hintergrund und Zielstellung: Schätzungen der Anzahl der Verstorbenen infolge der Influenzapandemien des 20. und 21. Jahrhunderts (1918/1919, 1957/1958, 1968–1970 und 2009) sind weltweit und auch für Deutschland eine Herausforderung. Die aufgrund einer systematischen Literaturrecherche erhobenen Ergebnisse sollen zusammengetragen, durch eigene Berechnungen ergänzt und bewertet werden. Methoden: Es wurde eine systematische Literaturrecherche unter Verwendung u. a. der Begriffe death, mortality, pandemic, epidemic, Germany, 1918, 1957, 1968, 2009 durchgeführt. Treffer wurden nach Titel bzw. Zusammenfassung gesichtet und bezüglich möglicher Relevanz selektiert. Eigene Schätzungen wurden, basierend auf Exzess-Mortalitäts-Berechnungen, durchgeführt. Die verschiedenen Werte aus der Literatur und den gegebenenfalls eigenen Berechnungen wurden bezüglich Methodik und Qualität der Datengrundlage bewertet, um den jeweils vertrauenswürdigsten zu identifizieren. Aus den Todesfallzahlen wurde für jede Pandemie eine Letalität berechnet und mit globalen Werten der Weltgesundheitsorganisation (WHO) verglichen. Ergebnisse: Für die Pandemie 1918/1919 identifizierten wir 5, für die Pandemien 1957/1958 und/oder 1968–1970 3 und für die Pandemie 2009 ebenfalls 3 relevante Publikationen. Für alle 4 Pandemien waren die plausibelsten Schätzungen diejenigen, welche mittels einer Zeitreihenanalyse (aus der Literatur entnommen oder aufgrund eigener Schätzungen) monatlicher oder wöchentlicher Gesamttodesfallstatistiken ermittelt wurden. Diese waren für die 4 Pandemien in chronologischer Reihenfolge 426.600 (1918/1919), 29.100 (1957/1958), 46.900 (1968–1970) bzw. 350 (2009) und entsprachen einer bevölkerungsbezogenen Exzess-Mortalität zwischen 691/100.000 (0,69 %) infolge der Pandemie 1918/1919 und 0,43/100.000 (0,00043 %) für 2009. Die resultierenden Letalitäten stimmten gut mit globalen, von der WHO angegebenen Werten überein. Schlussfolgerungen: Für die letzten 4 Pandemien (1918 bis 2009) konnten plausible Schätzungen der Exzess-Todesfallzahlen identifiziert werden. Die Heterogenität der entsprechenden Exzess-Mortalität zwischen den Pandemien ist bei einem Faktor von mehr als 1000 enorm. Diese kann durch Eigenschaften des Virus oder des Wirts (Immunität), die jeweiligen gesellschaftlichen Bedingungen, die Gesundheitsversorgung oder die medizinische Entwicklung bedingt sein.
sj-pdf-2-psp-10.1177_01461672211030125 – Supplemental material for Open to Contact? Increased State Openness Can Lead to Greater Interest in Contact With Diverse Groups
Creators: name: Hotchin, Victoria
name: West, Keon
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-pdf-2-psp-10.1177_01461672211030125 for Open to Contact? Increased State Openness Can Lead to Greater Interest in Contact With Diverse Groups by Victoria Hotchin and Keon West in Personality and Social Psychology Bulletin
sj-docx-1-tab-10.1177_1759720X211033679 – Supplemental material for Switching from originator adalimumab to biosimilar SB5 in a rheumatology cohort: persistence on treatment, predictors of drug interruption and safety analysis
Creators: name: Bruni, Cosimo
name: Gentileschi, Stefano
name: Pacini, Giovanni
name: Bardelli, Marco
name: Tofani, Lorenzo
name: Bartoli, Francesca
name: Baldi, Caterina
name: Cometi, Laura
name: Fiori, Ginevra
name: Nacci, Francesca
name: Cantarini, Luca
name: Guiducci, Serena
name: Moggi-Pignone, Alberto
name: Frediani, Bruno
name: Matucci-Cerinic, Marco
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-tab-10.1177_1759720X211033679 for Switching from originator adalimumab to biosimilar SB5 in a rheumatology cohort: persistence on treatment, predictors of drug interruption and safety analysis by Cosimo Bruni, Stefano Gentileschi, Giovanni Pacini, Marco Bardelli, Lorenzo Tofani, Francesca Bartoli, Caterina Baldi, Laura Cometi, Ginevra Fiori, Francesca Nacci, Luca Cantarini, Serena Guiducci, Alberto Moggi-Pignone, Bruno Frediani and Marco Matucci-Cerinic in Therapeutic Advances in Musculoskeletal Disease
Assessment of crocodile abundance and seasonal effects of salinity on distribution using both boat based and aerial drone surveys
Creators: name: Black, Jenell
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Animal behaviour
Animal physiological ecology
Marine and estuarine ecology (incl. marine ichthyology)

description: The American crocodile (Crocodylus acutus) is a common resident of Central American waterways, with one of the largest ranges of all crocodilians. It is very salt-tolerant, with only Nile crocodiles and Saltwater crocodiles superseding it in terms of being the most saline tolerant. Globally it has lost 9% of its range, with habitat destruction and fragmentation as the leading threat to this species. Overall there is a great need to understand the habitat uses by this species in order to mitigate consequences of further anthropogenic incursions along its range. Thus, this study aims to investigate seasonal effects of salinity on habitat selection of American crocodiles in a natural mangrove habitat, and to validate use of a commercial drone as a surveying tool for crocodilians in such habitats.
 This study found that as the seasons shift from wet to dry there was an associated increase in salinity of the estuarine waterway that resulted in an increase in the halocline of the estuary waters the greater the distance from the ocean. When broken down into the following groups: Hatchlings and juveniles (HJ) vs subadults and adults (SbA) it was found that salinity as well as season both had a correlation with the presence of crocodiles from the HJ group (p Surveys taken via drone were as efficacious as surveys taken diurnally via boat, with a survey encounter rate of 0.40 km-1, but still less efficacious than nocturnal eyeshine surveys, which had an encounter rate between 1.2 – 2.9 km-1. The drone was able to identify animals that were submerged under water, but was unable to ID animals resting on banks in thick mangroves. However, the drone was able to identify crocodiles as small as 0.7m. Further, the drone showed encounter rates for sharks and rays that were much higher than crocodiles, 0.84km-1 and 0.64km-1 respectively.
Additional file 2 of Knowledge, protective behaviours, and perception of Lyme disease in an area of emerging risk: results from a cross-sectional survey of adults in Ottawa, Ontario
Creators: name: Logan, James J.
name: Sawada, Michael
name: Knudby, Anders
name: Ramsay, Tim
name: Blanford, Justine I.
name: Ogden, Nicholas H.
name: Kulkarni, Manisha A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 2
Supplemental Material, sj-pdf-1-cpc-10.1177_10556656211031411 - Emotional and Behavioral Problems in Children With a Cleft Lip With or Without Palate or an Infantile Hemangioma
Creators: name: van Dalen, Marije
name: Hermans, Mireille M.
name: Leemreis, Willem H.
name: Kraaij, Vivian
name: De Laat, Peter C. J.
name: Pasmans, Suzanne G. M. A.
name: Versnel, Sarah L.
name: Koudstaal, Maarten J.
name: Hillegers, Manon H. J.
name: Utens, Elisabeth M. W. J.
name: Okkerse, Jolanda M. E.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental Material, sj-pdf-1-cpc-10.1177_10556656211031411 for Emotional and Behavioral Problems in Children With a Cleft Lip With or Without Palate or an Infantile Hemangioma by Marije van Dalen, Mireille M. Hermans, Willem H. Leemreis, Vivian Kraaij, Peter C. J. De Laat, Suzanne G. M. A. Pasmans, Sarah L. Versnel, Maarten J. Koudstaal, Manon H. J. Hillegers, Elisabeth M. W. J. Utens and Jolanda M. E. Okkerse in The Cleft Palate-Craniofacial Journal
Additional file 3 of Knowledge, protective behaviours, and perception of Lyme disease in an area of emerging risk: results from a cross-sectional survey of adults in Ottawa, Ontario
Creators: name: Logan, James J.
name: Sawada, Michael
name: Knudby, Anders
name: Ramsay, Tim
name: Blanford, Justine I.
name: Ogden, Nicholas H.
name: Kulkarni, Manisha A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 3