cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Assessment of the area measurement on Cartosat-1 image
Creators: name: Pluto-Kossakowska, Joanna
name: Grandgirard, David
name: Zielinski, Rafal
name: Kay, Simon
Publisher: name: arXiv
Year: 2024
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: The goal of this study was the evaluation of agriculture parcel area measurement accuracy on Cartosat-1 imagery, and the determination of the technical tolerance appropriate for measurement using photointerpretation techniques. A further objective was to find out the influence of image type, land cover or parcel size on the area measurement variability. In our experiment, five independent operators measured 185 parcels, 3 times, on each image. Next, the buffer width, calculated as the difference between measured and reference parcel area, was derived and was the subject of statistical analysis. Prior to verifying the normality of the buffer widths, a detection of anomalous measurements is recommended. This detection of outliers within each group of observations (i.e. parcels) was made using the Jacknife distance test on each type of imagery (Cartosat Aft, Cartosat Fore). Then, the General Linear Model procedure to identify major significant effects and interactions was followed by analysis of variance to ease the interpretation of the variability observed of the area measurement. Finally, two different parameters, reproducibility limit and critical difference, were calculated to make comparison with other sensors like digital aerial orthophoto in this study possible. The repeatability limits gave the acceptability difference between two operators when measuring the same parcel. For orthophoto this value reached 2.86m, on Cartosat-1 5.17m and 8.76m for Aft and Fore image respectively.
Growth of hydroxyapatite in a biocompatible mesoporous ordered silica
Creators: name: Diaz, A.
name: Lopez, T.
name: Manjarrez, J.
name: Basaldella, E.
name: Martinez-Blanes, J. M.
name: Odriozola, J. A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: A novel biomaterial (HA,SBA15) has been developed based on the growth of calcium phosphate hydroxyapatite (HA) nanoparticles within an organized silica structure (SBA15)
Implications of spatio-temporal land use/cover changes for ecosystem services supply in the coastal landscapes of Southwestern Ghana, West Africa
Creators: name: Kankam, Stephen
name: Osman, Adams
name: Inkoom, Justice Nana
name: Fürst, Christine
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 556

description: Land use/land cover change (LULCC) is an important driver of ecosystem changes in coastal areas. Despite being pervasive in coastal Ghana, LULCC has not been investigated to understand its effects on the potential for coastal landscapes to supply ecosystem services (ES). In this study, the impacts of LULCC on the potential supply of ES by coastal landscapes in Southwestern Ghana was assessed for the years 2008 and 2018 by using remote sensing and benefit transfer approaches. Based on available data, relevant provisioning and regulating ES were selected for the assessment while indicators to aid the quantification of the ES were obtained from literature. Supervised classification methods and maximum likelihood algorithms were used to prepare land use/land cover (LULC) maps and the derived LULC categories were assigned according to the descriptions of the Land Cover Classification System (LCCS). Potential supply of provisioning (food, fuelwood) and regulating (carbon storage) services was quantified and the spatial and temporal distributions of these ES illustrated using maps. The results show variations in food and fuelwood supply and carbon storage potentials over the study period and across different locations on the landscape. Potentials for fuelwood supply and carbon storage in mangrove forests indicated declining trends between 2008 and 2018. On the other hand, food-crop supply and carbon storage potential in rubber plantations depicted increasing patterns over the same period. Population, slope and elevation exhibited strong effects on LULC conversions to food crop and rubber plantations whereas these factors were less important determinants of mangrove forest conversions. The findings of the study have implications for identifying and addressing tradeoffs between land uses for agriculture, industrial development and conservation of critical coastal ES within the context of rapid land system transformations in the study region.
The use of wire mesh-flexible cementitious polymer composite for strengthening reinforced concrete beams
Creators: name: Manikka Arachchi, Himasara
name: Chandima Chathuranga Somarathna, H.M.
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 400505
subject: Construction materials
classificationCode: 400502
subject: Civil geotechnical engineering
classificationCode: 480502
subject: Civil procedure

description: The study investigates the use of wire mesh-flexible cementitious polymer composite to strengthen reinforced concrete (RC) beams. Control beams having the size of 600mm ×150mm ×150mm, were reinforced longitudinally with four 8 mm TOR steel bars and laterally with six 6 mm mild steel bars. The feasibility of the proposed method was investigated by altering steel mesh layers, employing a flexible polymer and 3 mm wire mesh. Control, one layer, two layers, and three layers of mesh-polymer composite specimens were used to evaluate the effect of different coating arrangements. Following ASTM C293 guidelines, four-point bending test was conducted and the time, load, and deflection were monitored. Findings showed that significant advancements were made by adding more layers of wire mesh. In contrast to the control, the stress and strain capacities were significantly improved, particularly with three layers having the maximum improvements of 121.67% for stress and 194% for strain. The energy at failure and the energy at design stress were similarly enhanced by layering, showcasing up to 5.59 times increased energy absorption capacity. The composite's effectiveness was derived from better load distribution, improved bonding between wire mesh and specimen, and additional mesh support. This combination improved energy absorption and deformation capacity by causing shear fractures instead of flexural tension cracks.The retrofitting method was economical, simple, and required little knowledge or equipment. The implications for the construction sector are significant, indicating that this method effectively and affordably improves RC beam characteristics. The work contributes to structural engineering by addressing beams using novel techniques such as wire mesh-polymer composite retrofitting and provides a possible option for enhancing the performance and lifespan of existing structures.
Cerebrospinal fluid cytochemical analysis from COVID-19 patients with neurological disorders
Creators: name: Walttuoni Picón, Eder
Publisher: name: figshare
Year: 2023
Subjects: Clinical neuropsychology
Metabolic medicine
Analytical biochemistry

description: Background: The COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people around the world. Most cytochemical studies of cerebrospinal fluid (CSF) in patients infected with SARS-CoV-2 have shown abnormal results. The objective of the present investigation was to determine the physical, cytological, and chemical alterations of the CSF cytochemical examination of COVID-19 patients with neurological disorders in Peru. Methods: An observational and cross-sectional study was carried out at the Edgardo Rebagliati Martins Hospital. The study population consisted of 94 CSF samples obtained by lumbar puncture from inpatient patients. Likewise, the paired T-test and one-way ANOVA with the Bonferroni post-hoc test was used to determine the differences in the values of CSF biochemical markers. Results: The most frequent neurological disorders were encephalopathy (43%) and brain tumor (23%). The most relevant physical characteristics were cloudy and reddish fluids in the brain tumor and intracerebral hemorrhage; however, in encephalopathies, transparent-looking liquids were observed. CSF glucose from patients with encephalopathy (30%) and intracerebral hemorrhage (13%) had concentrations >70 mg/dL. Proteins >45mg/dl corresponded to 20% of patients with encephalopathy and 17% of patients with intracerebral hemorrhage and brain tumor. Likewise, no differences were found in glucose concentration between neurological disorders (p>0.05); however, differences in protein concentration were observed (p=0.001). Finally, among the cytological characteristics, it was found that patients with encephalopathy (33%) and brain tumor (20%) presented a leukocyte count <5 cells/ul. Conclusion: These findings suggest that the characteristics of CSF may differ depending on the type of neurological complication experienced by patients with COVID-19.
Bridging the Domain Gap: A Simple Domain Matching Method for Reference-based Image Super-Resolution in Remote Sensing
Creators: name: Min, Jeongho
name: Lee, Yejun
name: Kim, Dongyoung
name: Yoo, Jaejun
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Recently, reference-based image super-resolution (RefSR) has shown excellent performance in image super-resolution (SR) tasks. The main idea of RefSR is to utilize additional information from the reference (Ref) image to recover the high-frequency components in low-resolution (LR) images. By transferring relevant textures through feature matching, RefSR models outperform existing single image super-resolution (SISR) models. However, their performance significantly declines when a domain gap between Ref and LR images exists, which often occurs in real-world scenarios, such as satellite imaging. In this letter, we introduce a Domain Matching (DM) module that can be seamlessly integrated with existing RefSR models to enhance their performance in a plug-and-play manner. To the best of our knowledge, we are the first to explore Domain Matching-based RefSR in remote sensing image processing. Our analysis reveals that their domain gaps often occur in different satellites, and our model effectively addresses these challenges, whereas existing models struggle. Our experiments demonstrate that the proposed DM module improves SR performance both qualitatively and quantitatively for remote sensing super-resolution tasks.
description: Accepted to IEEE GRSL 2023
In vitro models as tools for screening treatment options of head and neck cancer
Creators: name: Seliger, Barbara
name: Al-Samadi, Ahmed
name: Yang, Bo
name: Salo, Tuula
name: Wickenhauser, Claudia
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Various in vitro models using primary and established 2- and 3-dimensional cultures, multicellular tumor spheroids, standardized tumor slice cultures, tumor organoids, and microfluidic systems obtained from tumor lesions/biopsies of head and neck cancer (HNC) have been employed for exploring and monitoring treatment options. All of these in vitro models are to a different degree able to capture the diversity of tumors, recapitulate the disease genetically, histologically, and functionally and retain their tumorigenic potential upon xenotransplantation. The models were used for the characterization of the malignant features of the tumors and for in vitro screens of drugs approved for the treatment of HNC, including chemotherapy and radiotherapy as well as recently developed targeted therapies and immunotherapies, or for novel treatments not yet licensed for these tumor entities. The implementation of the best suitable model will enlarge our knowledge of the oncogenic properties of HNC, expand the drug repertoire and help to develop individually tailored treatment strategies resulting in the translation of these findings into the clinic. This review summarizes the different approaches using preclinical in vitro systems with their advantages and disadvantages and their implementation as preclinical platforms to predict disease course, evaluate biomarkers and test therapy efficacy.
Pathwise Stieltjes integrals of discontinuously evaluated stochastic processes
Creators: name: Chen, Zhe
name: Leskelä, Lasse
name: Viitasaari, Lauri
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 60H05, 60G22, 26A33, 60G07, 60G15

description: In this article we study the existence of pathwise Stieltjes integrals of the form $\int f(X_t)\, dY_t$ for nonrandom, possibly discontinuous, evaluation functions $f$ and Hölder continuous random processes $X$ and $Y$. We discuss a notion of sufficient variability for the process $X$ which ensures that the paths of the composite process $t \mapsto f(X_t)$ are almost surely regular enough to be integrable. We show that the pathwise integral can be defined as a limit of Riemann-Stieltjes sums for a large class of discontinuous evaluation functions of locally finite variation, and provide new estimates on the accuracy of numerical approximations of such integrals, together with a change of variables formula for integrals of the form $\int f(X_t) \, dX_t$.
description: The 2nd version contains lots of new examples illustrating applications of the main results to various stochastic processes
Safety and audiological outcome in a case series of tertiary therapy of sudden hearing loss with a biodegradable drug delivery implant for controlled release of dexamethasone to the inner ear
Creators: name: Plontke, Stefan K.-R.
name: Liebau, Arne
name: Lehner, Eric
name: Bethmann, Daniel
name: Mäder, Karsten
name: Rahne, Torsten
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Background: Intratympanic injections of glucocorticoids have become increasingly common in the treatment of idiopathic sudden sensorineural hearing loss (ISSHL). However, due to their fast elimination, sustained applications have been suggested for local drug delivery to the inner ear. Materials and methods: The study is based on a retrospective chart review of patients treated for ISSHL at a single tertiary (university) referral center. We included patients who were treated with a solid, biodegradable, poly(D,L-lactic-co-glycolic acid) (PLGA)-based drug delivery system providing sustained delivery of dexamethasone extracochlear into the round window niche (n = 15) or intracochlear into scala tympani (n = 2) for tertiary therapy of ISSHL in patients without serviceable hearing after primary systemic and secondary intratympanic glucocorticoid therapy. We evaluated the feasibility and safety through clinical evaluation, histological examination, and functional tests [pure-tone threshold (PTA), word recognition scores (WRS)]. Results: With adequate surgical preparation of the round window niche, implantation was feasible in all patients. Histologic examination of the material in the round window niche showed signs of resorption without relevant inflammation or foreign body reaction to the implant. In patients where the basal part of scala tympani was assessable during later cochlear implantation, no pathological findings were found. In the patients with extracochlear application, average preoperative PTA was 84.7 dB HL (SD: 20.0) and 76.7 dB HL (SD: 16.7) at follow-up (p = 0.08). The preoperative average maximum WRS was 14.6% (SD: 17.9) and 39.3% (SD: 30.7) at follow-up (p = 0.11). Six patients (40%), however, reached serviceable hearing. The two patients with intracochlear application did not improve. Conclusion: The extracochlear application of the controlled release system in the round window niche and – based on limited observations - intracochlear implantation into scala tympani appears feasible and safe. Due to the uncontrolled study design, conclusions about the efficacy of the treatment are limited. These observations, however, may encourage the initiation of prospective controlled studies using biodegradable controlled release implants as drug delivery systems for the treatment of inner ear diseases.
EchoPFL: Asynchronous Personalized Federated Learning on Mobile Devices with On-Demand Staleness Control
Creators: name: Li, Xiaochen
name: Liu, Sicong
name: Zhou, Zimu
name: Guo, Bin
name: Xu, Yuan
name: Yu, Zhiwen
Publisher: name: arXiv
Year: 2024
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: The rise of mobile devices with abundant sensory data and local computing capabilities has driven the trend of federated learning (FL) on these devices. And personalized FL (PFL) emerges to train specific deep models for each mobile device to address data heterogeneity and varying performance preferences. However, mobile training times vary significantly, resulting in either delay (when waiting for slower devices for aggregation) or accuracy decline (when aggregation proceeds without waiting). In response, we propose a shift towards asynchronous PFL, where the server aggregates updates as soon as they are available. Nevertheless, existing asynchronous protocols are unfit for PFL because they are devised for federated training of a single global model. They suffer from slow convergence and decreased accuracy when confronted with severe data heterogeneity prevalent in PFL. Furthermore, they often exclude slower devices for staleness control, which notably compromises accuracy when these devices possess critical personalized data. Therefore, we propose EchoPFL, a coordination mechanism for asynchronous PFL. Central to EchoPFL is to include updates from all mobile devices regardless of their latency. To cope with the inevitable staleness from slow devices, EchoPFL revisits model broadcasting. It intelligently converts the unscalable broadcast to on-demand broadcast, leveraging the asymmetrical bandwidth in wireless networks and the dynamic clustering-based PFL. Experiments show that compared to status quo approaches, EchoPFL achieves a reduction of up to 88.2% in convergence time, an improvement of up to 46% in accuracy, and a decrease of 37% in communication costs
description: accepted by Ubicomp2024
Zero-Energy Modes from Coalescing Andreev States in a Two-Dimensional Semiconductor-Superconductor Hybrid Platform
Creators: name: Suominen, Henri J.
name: Kjaergaard, Morten
name: Hamilton, Alexander R.
name: Shabani, Javad
name: Palmstrøm, Chris J.
name: Marcus, Charles M.
name: Nichele, Fabrizio
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We investigate zero-bias conductance peaks that arise from coalescing subgap Andreev states, consistent with emerging Majorana zero modes, in hybrid semiconductor-superconductor wires defined in a two-dimensional InAs/Al heterostructure using top-down lithography and gating. The measurements indicate a hard superconducting gap, ballistic tunneling contact, and in-plane critical fields up to $3$~T. Top-down lithography allows complex geometries, branched structures, and straightforward scaling to multicomponent devices compared to structures made from assembled nanowires.
description: Includes Supplementary Material
Additional file 1 of The diversity of providers’ and consumers’ views of virtual versus inpatient care provision: a qualitative study
Creators: name: Clay-Williams, Robyn
name: Hibbert, Peter
name: Carrigan, Ann
name: Roberts, Natalie
name: Austin, Elizabeth
name: Fajardo Pulido, Diana
name: Meulenbroeks, Isabelle
name: Nguyen, Hoa Mi
name: Sarkies, Mitchell
name: Hatem, Sarah
name: Maka, Katherine
name: Loy, Graeme
name: Braithwaite, Jeffrey
Publisher: name: figshare
Year: 2023
Subjects: subject: Ecology
subject: FOS: Biological sciences
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 80699
subject: Information Systems not elsewhere classified
subject: Science Policy
classificationCode: 110309
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Consumer focus group script.
Interpolating sequences in spaces with the complete Pick property
Creators: name: Aleman, Alexandru
name: Hartz, Michael
name: McCarthy, John E.
name: Richter, Stefan
Publisher: name: arXiv
Year: 2017
Subjects: subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 46E22

description: We characterize interpolating sequences for multiplier algebras of spaces with the complete Pick property. Specifically, we show that a sequence is interpolating if and only if it is separated and generates a Carleson measure. This generalizes results of Carleson for the Hardy space and of Bishop, Marshall and Sundberg for the Dirichlet space. Furthermore, we investigate interpolating sequences for pairs of Hilbert function spaces.
Genome-wide association study of salt tolerance-related traits during germination and seedling development in an intermedium-spike barley collection
Creators: name: Sayed, Mohammed A.
name: Maurer, Andreas
name: Schmutzer, Thomas
name: Schnurbusch, Thorsten
name: Börner, Andreas
name: Hansson, Mats
name: Pillen, Klaus
name: Youssef, Helmy M.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 580

description: Increased salinity is one of the major consequences of climatic change affecting global crop production. The early stages in the barley (Hordeum vulgare L.) life cycle are considered the most critical phases due to their contributions to final crop yield. Particularly, the germination and seedling development are sensitive to numerous environmental stresses, especially soil salinity. In this study, we aimed to identify SNP markers linked with germination and seedling development at 150 mM NaCl as a salinity treatment. We performed a genome-wide association study (GWAS) using a panel of 208 intermedium-spike barley (H. vulgare convar. intermedium (Körn.) Mansf.) accessions and their genotype data (i.e., 10,323 SNPs) using the genome reference sequence of “Morex”. The phenotypic results showed that the 150 mM NaCl salinity treatment significantly reduced all recorded germination and seedling-related traits compared to the control treatment. Furthermore, six accessions (HOR 11747, HOR 11718, HOR 11640, HOR 11256, HOR 11275 and HOR 11291) were identified as the most salinity tolerant from the intermedium-spike barley collection. GWAS analysis indicated that a total of 38 highly significantly associated SNP markers under control and/or salinity traits were identified. Of these, two SNP markers on chromosome (chr) 1H, two on chr 3H, and one on chr 4H were significantly linked to seedling fresh and dry weight under salinity stress treatment. In addition, two SNP markers on chr 7H were also significantly associated with seedling fresh and dry weight but under control condition. Under salinity stress, one SNP marker on chr 1H, 5H and 7H were detected for more than one phenotypic trait. We found that in most of the accessions exhibiting the highest salinity tolerance, most of the salinity-related QTLs were presented. These results form the basis for detailed studies, leading to improved salt tolerance breeding programs in barley.
title: The function of general principles in the practice of the European Court of Justice
Creators: name: Friend, Alan
Publisher: name: University of Glasgow
Year: 1983
Subjects: subject: International law, European Court of Justice, European studies.

description: The use by the European Court of Justice of General Principles of Law is the subject of this study. It relates to the way the Court refers to and the extent to which it relies upon General Principles. On occasion, the Court refers to General Principles as synonymous with rules, at other times as separate but not clearly defined entities. Equally noteworthy, the Court, despite its aforementioned reliance on General Principles, elaborates little on the functions General Principles fulfil. To sum up, the Court acts in an intellectually provocative manner. The major part of this thesis concerns the analysis of a number of cases involving General Principles from which certain contentions are derived and examined; that General Principles are an important source of European Community Law; that their use by the European Court of Justice has had a profound effect on European Community Law; that this area of law is an example of the dynamic tension between institutions and Community members, such tension being a natural consequence of a developing new legal order. This analysis is preceded by a basic explanation of General Principles and a survey of their use in various systems of municipal law and international law, such analysis providing a framework in which it is possible to analyse the work of the European Court of Justice. The thesis concludes with the observation that the above contentions are, in greater part, borne out and that General Principles are still and continue to be for the foreseeable future, an important source of European Community Law.
Peer-ness or Deference?: Face-to-Face Summit Performances and Public Opinion in Korea-U.S. Alliance
Creators: name: Park, Jeonghoon
Publisher: name: University of Chicago
Year: 2022
Subjects: subject: Diplomacy
subject: Face-to-face diplomacy
subject: Alliance
subject: Korea-U.S. relationship
subject: Summitry
subject: Public opinion
subject: Visual performance of summitry

description: Why do leaders of states engage in face-to-face diplomacy? The existing answers to this question largely focus on the private effect of the leaders engaging in the face-to-face meeting or on the public effects created by the mere occurrences of the meetings. This research aims to innovate by looking at the public and the performance side of face-to-face summit diplomacy in the context of the bilateral alliance. The non-substantive visual performances of face-to-face summit meetings can signal the relational status of the summits to the public. I argue that the performances of equivalence (peer-ness) or hierarchy (deference) between the summits affect the domestic public opinion, which ultimately affects the prospect for alliance coordination. In a bilateral alliance, a government can face a dilemma between the conflicting demands of the ally and of its own citizens, which I will coin as the “alliance-public dilemma.” In the Korea-U.S. alliance, the Korean public wants its government to maintain a close and friendly relationship with the U.S. strategically but does not want it to show a weaker and losing stance vis-à-vis the U.S. emotionally. This dual demand puts the Korean government in a dilemma between (1)having to strategically coordinate with (make concessions to) the U.S. and (2)satisfying its citizens, that are highly sensitive to the implicit hierarchy of the two countries. The Korean government can alleviate the dilemma by winning public support through deliberately performing friendliness and peer-ness in face-to-face summit meetings. I studied 17 Korea-U.S. summit meetings during 2002-2021 held in bilateral visits and provided 5 selected case studies. The cases show that a high level of peer-ness performed is linked to high public approval of summitry or to the increased presidential approval rate, while the high level of deference performed is linked to the opposite result, on the condition that the two summits showed friendly relationship.
Physiochemical Response of the Lichen genus Everniastrum as Bioindicator of Ambient Air Nitrogen Deposition along with an Elevation Gradient in a Temperate-alpine Habitat of Western Himalaya
Creators: name: Rai, Himanshu
name: Khare, Roshni
name: Gupta, Rajan Kumar
name: Ade, Avinash B
Publisher: name: figshare
Year: 2023
Subjects: Mycology
Plant physiology
Plant biology not elsewhere classified

description: The high elevation habitats of the Himalayas in the past few decades are experiencing intense land use changes due to tourism-related anthropogenic activities. These habitats receive moderate to higher deposition of Nitrogen through vehicular, agricultural practices, and other urban exhausts. Nitrophobic lichens of the family Parmeliaceae largely populate the high elevation habitats. The current study explores the capability of the Parmelioid genus Everniastrum as a bioindicator of nitrogen pollution in a temperate-alpine habitat. The study explored the correlation between the nitrogen accumulation in the thallus of two common Everniastrum species of the landscape to the photobiont chlorophyll, carotenoids, and chlorophyll degradation. The study concluded that one of the species Everniastrum cirrhatum can be an appropriate bioindicator of ambient air N deposition and can be used in long-term biomonitoring experiments.
Additional file 2 of The diversity of providers’ and consumers’ views of virtual versus inpatient care provision: a qualitative study
Creators: name: Clay-Williams, Robyn
name: Hibbert, Peter
name: Carrigan, Ann
name: Roberts, Natalie
name: Austin, Elizabeth
name: Fajardo Pulido, Diana
name: Meulenbroeks, Isabelle
name: Nguyen, Hoa Mi
name: Sarkies, Mitchell
name: Hatem, Sarah
name: Maka, Katherine
name: Loy, Graeme
name: Braithwaite, Jeffrey
Publisher: name: figshare
Year: 2023
Subjects: subject: Ecology
subject: FOS: Biological sciences
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 80699
subject: Information Systems not elsewhere classified
subject: Science Policy
classificationCode: 110309
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. Provide focus group script.
Supersymmetry in a dynamical M-brane background
Creators: name: Maeda, Kengo
name: Uzawa, Kunihito
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The supersymmetry arises in certain theories of fermions coupled to gauge fields and gravity in a spacetime of 11 dimensions. The dynamical brane background has mainly been studied for the class of purely bosonic solutions only, but recent developments involving a time-dependent brane solution have made it clear that one can get more information by asking what happens on supersymmetric systems. In this paper, we construct an exact supersymmetric solution of a dynamical M-brane background in the 11-dimensional supergravity and investigate supersymmetry breaking, the geometric features near the singularity and the black hole horizon.
description: 24 pages, typos corrected, Journal version
A multigene phylogeny of native American hawkweeds (Hieracium Subgen. Chionoracium, Cichorieae, Asteraceae) : origin, speciation patterns, and migration routes
Creators: name: Fehrer, Judith
name: Bertrand, Yann J. K.
name: Hartmann, Matthias
name: Caklová, Petra
name: Josefiová, Jirina
name: Bräutigam, Siegfried
name: Chrtek, Jindřich
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 580

description: Native American hawkweeds are mainly mountainous species that are distributed all over the New World. They are severely understudied with respect to their origin, colonization of the vast distribution area, and species relationships. Here, we attempt to reconstruct the evolutionary history of the group by applying seven molecular markers (plastid, nuclear ribosomal and low-copy genes). Phylogenetic analyses revealed that Chionoracium is a subgenus of the mainly Eurasian genus Hieracium, which originated from eastern European hawkweeds about 1.58–2.24 million years ago. Plastid DNA suggested a single origin of all Chionoracium species. They colonized the New World via Beringia and formed several distinct lineages in North America. Via one Central American lineage, the group colonized South America and radiated into more than a hundred species within about 0.8 million years, long after the closure of the Isthmus of Panama and the most recent uplift of the Andes. Despite some incongruences shown by different markers, most of them revealed the same crown groups of closely related taxa, which were, however, largely in conflict with traditional sectional classifications. We provide a basic framework for further elucidation of speciation patterns. A thorough taxonomic revision of Hieracium subgen. Chionoracium is recommended.
Gravity is not a Pairwise Local Classical Channel
Creators: name: Altamirano, Natacha
name: Corona-Ugalde, Paulina
name: Mann, Robert B.
name: Zych, Magdalena
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is currently believed that there is no experimental evidence on possibly quantum features of gravity or gravity-motivated modifications of quantum mechanics. Here we show that single-atom interference experi- ments achieving large spatial superpositions can rule out a framework where the Newtonian gravitational inter- action is fundamentally classical in the information-theoretic sense: it cannot convey entanglement. Specifically, in this framework gravity acts pairwise between massive particles as classical channels, which effectively induce approximately Newtonian forces between the masses. The experiments indicate that if gravity does reduce to the pairwise Newtonian interaction between atoms at the low energies, this interaction cannot arise from the exchange of just classical information, and in principle has the capacity to create entanglement. We clarify that, contrary to current belief, the classical-channel description of gravity differs from the model of Diosi and Penrose, which is not constrained by the same data.
description: 13 pages, 5 figures, 2 tables, Latex
Study of the HCCNC and HNCCC isotopologs in TMC-1
Creators: name: Cernicharo, José
name: Tercero, Belén
name: Cabezas, Carlos
name: Agúndez, Marcelino
name: Roueff, Evelyne
name: Fuentetaja, Raúl
name: Marcelino, Nuria
name: de Vicente, Pablo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present the detection of the three 13C isotopologs of HCCNC and HNCCC toward TMC-1 using the QUIJOTE line survey. In addition, the D species has also been detected for these two isomers of HCCCN, whereas the 15N isotopolog was only detected for HCCNC. Using high-J lines of HCCNC and HNCCC, we were able to derive very precise rotational temperatures, column densities, and subsequently the isotopic abundance ratios. We found that 12C/13C is around 90 for the three possible substitutions in both isomers. These results are slightly different from what has been found for the most abundant isomer HCCCN, for which abundances of 105, 95, and 66 were found for each one of the three possible positions of 13C. The H/D abundance ratio was found to be 31+/-4 for HCCNC and of 53+/-6 for HNCCC. The latter is similar to the H/D abundace ratio derived for HCCCN (59). The 14N/15N isotopic abundance ratio in HCCNC is 243+/-24.
description: Accepted as a Letter in Astronomy & Astrophysics on 22 January 2024
No impact of PolySia-NCAM expression on treatment response in neuroendocrine neoplasms of the lung
Creators: name: Gagiannis, Daniel
name: Scheil, Anna Christina
name: Gagiannis, Sarah
name: Hackenbroch, Carsten
name: Horstkorte, Rüdiger
name: Steinestel, Konrad Ernst
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2022
Subjects: subject: 610

description: Background: Polysialic acids (abbr. polySia) are found on numerous tumors, including neuroendocrine lung tumors. They have previously been shown to impact metastatic potential, as they can influence the signaling and adhesion properties of neuronal cell adhesion molecules (abbr. NCAM) and other cell adhesion molecules. Therefore, the aim of this small pilot study was to analyze whether there was a correlation between polySia-NCAM expression and specific clinical or histopathologic characteristics, and if polySia-NCAM expression had an impact on treatment response, disease progression and prognosis of lung neuroendocrine neoplasms. Methods: This work was based on an analysis of 28 digitized patient records and corresponding patient samples. The response to therapy was radiologically determined at the time of diagnosis and at certain intervals during therapy following the current RECIST1.1 and volumetric sphere calculation. To analyze whether polySia-NCAM expression had prognostic relevance, polySia-NCAM-positive and -negative cases were compared in a Kaplan-Meier survival analysis. Findings: A majority of 78.6% lung neuroendocrine neoplasms showed a strong staining signal for polySia-NCAM. There was a significant correlation between expression and histopathological grade (p = 0.0140), since carcinoids were less likely polySia-NCAM-positive compared to small cell lung carcinoma (abbr. SCLC) and large cell neuroendocrine carcinomas of the lung (abbr. LCNEC). There was no significant association between polySia-NCAM expression and clinical characteristics (age: p = 0.3405; gender: p = 0.6730; smoking history: p = 0.1145; ECOG: p = 0.1756, UICC8 stage: p = 0.1182) or radiologically determined disease progression, regardless of the criteria used to categorize response (RECIST 1.1: p = 0.0759; sphere: p = 0.0580). Furthermore, polySia-NCAM expression did not affect progression-free survival (p = 0.4198) or overall survival (p = 0.6918). Interpretation: PolySia-NCAM expression was more common in high-grade compared to low-grade neuroendocrine neoplasms of the lung; however, this small pilot study failed to show an association between polySia-NCAM expression and response to therapy.
Additional file 1 of Prognostic and predictive value of endothelial dysfunction biomarkers in sepsis-associated acute kidney injury: risk-stratified analysis from a prospective observational cohort of pediatric septic shock
Creators: name: Atreya, Mihir R.
name: Cvijanovich, Natalie Z.
name: Fitzgerald, Julie C.
name: Weiss, Scott L.
name: Bigham, Michael T.
name: Jain, Parag N.
name: Schwarz, Adam J.
name: Lutfi, Riad
name: Nowak, Jeffrey
name: Allen, Geoffrey L.
name: Thomas, Neal J.
name: Grunwell, Jocelyn R.
name: Baines, Torrey
name: Quasney, Michael
name: Haileselassie, Bereketeab
name: Alder, Matthew N.
name: Goldstein, Stuart L.
name: Stanski, Natalja L.
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
classificationCode: 69999
subject: Biological Sciences not elsewhere classified
classificationCode: 19999
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: Additional file 1. Clinical characteristics of patients according to PERSEVERE-II mortality class.
NOXA accentuates apoptosis induction by a novel histone deacetylase inhibitor
Creators: name: Ashry, Ramy
name: Mustafa, Al-Hassan M.
name: Hausmann, Kristin
name: Linnebacher, Michael
name: Strand, Susanne
name: Sippl, Wolfgang
name: Wirth, Matthias
name: Krämer, Oliver Holger
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 615

description: Epigenetic modifiers of the histone deacetylase (HDAC) family are often dysregulated in cancer cells. Experiments with small molecule HDAC inhibitors (HDACi) have proven that HDACs are a vulnerability of transformed cells. We evaluated a novel hydroxamic acid-based HDACi (KH16; termed yanostat) in human pancreatic ductal adenocarcinoma (PDAC) cells, short- and long-term cultured colorectal cancer (CRC) cells, and retinal pigment epithelial cells. We show that KH16 induces cell cycle arrest and apoptosis, both time and dose dependently in PDAC and CRC cells. This is associated with altered expression of BCL2 family members controlling intrinsic apoptosis. Recent data illustrate that PDAC cells frequently have an altered expression of the pro-apoptotic BH3-only protein NOXA and that HDACi induce an accumulation of NOXA. Using PDAC cells with a deletion of NOXA by CRISPR-Cas9, we found that a lack of NOXA delayed apoptosis induction by KH16. These results suggest that KH16 is a new chemotype of hydroxamic acid HDACi with superior activity against solid tumor-derived cells. Thus, KH16 is a scaffold for future research on compounds with nanomolar activity against HDACs.
LESSON: Multi-Label Adversarial False Data Injection Attack for Deep Learning Locational Detection
Creators: name: Tian, Jiwei
name: Shen, Chao
name: Wang, Buhong
name: Xia, Xiaofang
name: Zhang, Meng
name: Lin, Chenhao
name: Li, Qian
Publisher: name: arXiv
Year: 2024
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Deep learning methods can not only detect false data injection attacks (FDIA) but also locate attacks of FDIA. Although adversarial false data injection attacks (AFDIA) based on deep learning vulnerabilities have been studied in the field of single-label FDIA detection, the adversarial attack and defense against multi-label FDIA locational detection are still not involved. To bridge this gap, this paper first explores the multi-label adversarial example attacks against multi-label FDIA locational detectors and proposes a general multi-label adversarial attack framework, namely muLti-labEl adverSarial falSe data injectiON attack (LESSON). The proposed LESSON attack framework includes three key designs, namely Perturbing State Variables, Tailored Loss Function Design, and Change of Variables, which can help find suitable multi-label adversarial perturbations within the physical constraints to circumvent both Bad Data Detection (BDD) and Neural Attack Location (NAL). Four typical LESSON attacks based on the proposed framework and two dimensions of attack objectives are examined, and the experimental results demonstrate the effectiveness of the proposed attack framework, posing serious and pressing security concerns in smart grids.
description: Accepted by TDSC
Robust Multiplication-based Tests for Reed-Muller Codes
Creators: name: Harsha, Prahladh
name: Srinivasan, Srikanth
Publisher: name: arXiv
Year: 2016
Subjects: subject: Computational Complexity (cs.CC)
subject: FOS: Computer and information sciences

description: We consider the following multiplication-based tests to check if a given function $f: \mathbb{F}_q^n\to \mathbb{F}_q$ is a codeword of the Reed-Muller code of dimension $n$ and order $d$ over the finite field $\mathbb{F}_q$ for prime $q$ (i.e., $f$ is the evaluation of a degree-$d$ polynomial over $\mathbb{F}_q$ for $q$ prime). * $\mathrm{Test}_{e,k}$: Pick $P_1,\ldots,P_k$ independent random degree-$e$ polynomials and accept iff the function $fP_1\cdots P_k$ is the evaluation of a degree-$(d+ek)$ polynomial (i.e., is a codeword of the Reed-Muller code of dimension $n$ and order $(d+ek)$). We prove the robust soundness of the above tests for large values of $e$, answering a question of Dinur and Guruswami [Israel Journal of Mathematics, 209:611-649, 2015]. Previous soundness analyses of these tests were known only for the case when either $e=1$ or $k=1$. Even for the case $k=1$ and $e>1$, earlier soundness analyses were not robust. We also analyze a derandomized version of this test, where (for example) the polynomials $P_1,\dots,P_k$ can be the same random polynomial $P$. This generalizes a result of Guruswami et al. [SIAM J. Comput., 46(1):132-159, 2017]. One of the key ingredients that go into the proof of this robust soundness is an extension of the standard Schwartz-Zippel lemma over general finite fields $\mathbb{F}_q$, which may be of independent interest.
Results of adjustable trans-obturator male system in patients with prostate cancer treated with prostatectomy and radiotherapy : a multicenter study
Creators: name: Angulo, Javier C.
name: Téllez, Carlos
name: Giammó, Alessandro
name: González-Enguita, Carmen
name: Schoenburg, Sandra
name: Queißert, Fabian
name: Szczesniewski, Juliusz
name: González, Raquel
name: Romero, Antonio
name: Gonsior, Andreas
name: Martins, Francisco E.
name: Antunes-Lopes, Tiago
name: Cruz, Francisco
name: Rourke, Keith
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 618

description: (1) Background: Treatment of male stress incontinence in patients with prostate cancer treated with radical prostatectomy and adjuvant pelvic radiation is a therapeutic challenge. The efficacy and safety of the adjustable trans-obturator male system (ATOMS) in these patients is not well established, despite the general belief that outcomes are worse than in patients without radiation. (2) Methods: Retrospective multicenter study evaluating patients treated with silicone-covered scrotal port (SSP) ATOMS implant after radical prostatectomy and radiotherapy in nine different institutions between 2016 and 2022. The primary endpoint was dry patient rate, defined as pad-test ≤ 20 mL/day. The secondary endpoints were complication rate (defined using Clavien–Dindo classification), device removal and self-perceived satisfaction using the Patient Global Impression of Improvement (PGI-I) scale. Wilcoxon rank-sum test, Fisher’s exact test and logistic regression were performed using stepwise method with a 0.15 entry and 0.1 stay criteria. (3) Results: 223 patients fulfilled the criteria for inclusion and 12 (5.4%) received salvage prostatectomy after radiation and 27 (12.1%) previous devices for stress incontinence. After ATOMS adjustment, 95 patients (42.6%) were dry and 36 (16.1%) had complications of any grade (grade I, n = 20; grade II, n = 11; grade III, n = 5) during the first 3 months postoperatively. At a mean of 36 ± 21 months follow-up, the device was explanted in 26 (11.7%) patients. Regarding self-perceived satisfaction with the implant, 105 of 125 patients (84%) considered themselves satisfied (PGI-I 1 to 3). In the univariate analysis, dryness was associated to younger age (p = 0.06), primary prostatectomy (p = 0.08), no previous incontinence surgery (p = 0.02), absence of overactive bladder symptoms (p = 0.04), absence of bladder neck stricture (p = 0.001), no need of surgical revision (p = 0.008) and lower baseline incontinence severity (p = 0.0003). Multivariate analysis identified absence of surgical revision (p = 0.018), absence of bladder neck stricture (p = 0.05), primary prostatectomy (p = 0.07) and lower baseline incontinence severity (p < 0.0001) were independent predictors of dryness. A logistic regression model was proposed and internally validated. (4) Conclusions: ATOMS is an efficacious and safe alternative to treat male incontinence after radical prostatectomy and adjuvant radiotherapy. Factors predictive of dryness are identified in this complex scenario to allow for better patient selection.