title: ÐÐ½Ð´ÑÐºÑÐ¸Ñ Ð°ÐºÑÐ¸Ð²Ð½ÑÑ ÑÐ¾ÑÐ¼ ÐºÐ¸ÑÐ»Ð¾ÑÐ¾Ð´Ð° ÐºÐ»ÐµÑÐºÐ°Ð¼Ð¸ ÐºÑÐ¾Ð²Ð¸ Ð¿ÑÐ¸ ÐµÐµ Ð²Ð·Ð°Ð¸Ð¼Ð¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ð¸ Ñ ÑÐ°Ð·Ð»Ð¸ÑÐ½ÑÐ¼Ð¸ Ð³ÐµÐ¼Ð¾ÑÐ¾ÑÐ±ÐµÐ½ÑÐ°Ð¼Ð¸
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Induction of reactive oxygen species by blood cells during its interaction with various hemosorbents
Creators: name: Ð Ð¾Ð¼Ð°Ð½ÑÑÐº, ÐÐ»Ð¸Ð·Ð°Ð²ÐµÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2020
Subjects: Ð°ÐºÑÐ¸Ð²Ð½ÑÐµ ÑÐ¾ÑÐ¼Ñ ÐºÐ¸ÑÐ»Ð¾ÑÐ¾Ð´Ð°
Ð»ÐµÐ¹ÐºÐ¾ÑÐ¸ÑÑ
Ð¼ÐµÑÐ¾Ð´ Ð¼Ð°Ð»Ð¾Ð¾Ð±ÑÐµÐ¼Ð½Ð¾Ð¹ Ð³ÐµÐ¼Ð¾Ð¿ÐµÑÑÑÐ·Ð¸Ð¸
Ð³ÐµÐ¼Ð¾ÐºÐ¾Ð½ÑÐ°ÐºÑÐ½ÑÐµ Ð¿ÑÐµÐ¿Ð°ÑÐ°ÑÑ
Ð²Ð¾Ð»Ð¾ÐºÐ½Ð° Ñ Ð¸ÑÐ¾Ð·Ð°Ð½Ð°
ÑÐ²ÐµÑÑ ÑÑÐ¸ÑÑÐ¹ Ð¿Ð¾Ð»Ð¸ÑÑÐ¸ÑÐ¾Ð»
ÐºÑÐµÐ¼Ð½ÐµÐ·ÐµÐ¼Ñ
reactive oxygen species
leukocytes
low-volume hemoperfusion
hemocontact preparations
chitosan fibers
hypercross-linked polystyrene
silica

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description: This work is devoted to the study of inductive and inhibitory capabilities (in terms of ROS generation) using luminol-dependent chemiluminescence of solid-phase hemocontact preparations (sorbents): SKT-6A high-frequency coal, SPS âStirosorb 516â, silica Silochrome S-120 and its derivatives (KSH, KSHF, TMFS, TMFS-K), chitosan fibers (BX 0%) and its derivatives modified with chitin nanofibrils (BX 0.5%, 5%, 30%, 50%) upon their contact interaction with blood in vitro. Of all the studied and control sorbents, hemosorbents from the group of silica gels - TMPS and TMFS-K, which are a composite of silica gel and transmalonylfullerene C60, have the greatest inductive capabilities of generating ROS by blood leukocytes. All sorbents of the chitosan group, modified with chitin nanofibrils, have a weak ability to start the process of ROS production of various intensities in blood cells. These properties are most noticeable in preparations of BX 0.5% and BX 50%. In zymosan-induced LHLC the studied drugs of both groups and the control show the properties of inhibiting the production of ROS by blood cells to various degrees.