cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An integrated chemical proteomics approach for quantitative profiling of intracellular ADP-ribosylation.
Creators: name: Kalesh, Karunakaran
name: Lukauskas, Saulius
name: Borg, Aaron J
name: Snijders, Ambrosius P
name: Ayyappan, Vinay
name: Leung, Anthony KL
name: Haskard, Dorian O
name: DiMaggio, Peter A
Publisher: name: The Francis Crick Institute
Year: 2020
Subjects: Chemical Biology & High Throughput
Biochemistry & Proteomics
Computational & Systems Biology

description: ADP-ribosylation is integral to a diverse range of cellular processes such as DNA repair, chromatin regulation and RNA processing. However, proteome-wide investigation of its cellular functions has been limited due to numerous technical challenges including the complexity of the poly(ADP-ribose) (PAR) chains, low abundance of the modification and lack of sensitive enrichment methods. We herein show that an adenosine analogue with a terminal alkyne functionality at position 2 of the adenine (2-alkyne adenosine or 2YnAd) is suitable for selective enrichment, fluorescence detection and mass spectrometry proteomics analysis of the candidate ADP-ribosylome in mammalian cells. Although similar labelling profiles were observed via fluorescence imaging for 2YnAd and 6YnAd, a previously reported clickable NAD+ precursor, quantitative mass spectrometry analysis of the two probes in MDA-MB-231 breast cancer cells revealed a significant increase in protein coverage of the 2YnAd probe. To facilitate global enrichment of ADP-ribosylated proteins, we developed a dual metabolic labelling approach that involves simultaneous treatment of live cells with both 2YnAd and 6YnAd. By combining this dual metabolic labelling strategy with highly sensitive tandem mass tag (TMT) isobaric mass spectrometry and hierarchical Bayesian analysis, we have quantified the responses of thousands of endogenous proteins to clinical PARP inhibitors Olaparib and Rucaparib.
Nonlinear Quantum Rabi Model in Trapped Ions
Creators: name: Cheng, Xiao-Hang
name: Arrazola, Iñigo
name: Pedernales, Julen S.
name: Lamata, Lucas
name: Chen, Xi
name: Solano, Enrique
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the nonlinear dynamics of trapped-ion models far away from the Lamb-Dicke regime. This nonlinearity induces a sideband cooling blockade, stopping the propagation of quantum information along the Hilbert space of the Jaynes-Cummings and quantum Rabi models. We compare the linear and nonlinear cases of these models in the ultrastrong and deep strong coupling regimes. Moreover, we propose a scheme that simulates the nonlinear quantum Rabi model in all coupling regimes. This can be done via off-resonant nonlinear red and blue sideband interactions, yielding applications as a dynamical quantum filter.
Dorycnium hirsutum Ser.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Dorycnium
Dorycnium hirsutum

description: Lotus hirsutus Linnaeus, Species Plantarum 2: 775. 1753.
"Habitat in G. Narbonensi, Italia." RCN: 5696.
 Lectotype (Jafri in Jafri & El-Gadi, Fl. Libya 86: 112. 1980): Herb. Linn. No. 931.16 (LINN).
 Current name: Dorycnium hirsutum (L.) Ser. (Fabaceae: Faboideae).
 Note: Specific epithet spelled “hirsuta” in the protologue.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 642, DOI: 10.5281/zenodo.291971
Observation of a critical prethermal discrete time crystal created by two-frequency driving
Creators: name: Beatrez, William
name: Fleckenstein, Christoph
name: Pillai, Arjun
name: Sanchez, Erica
name: Akkiraju, Amala
name: Alcala, Jesus
name: Conti, Sophie
name: Reshetikhin, Paul
name: Druga, Emanuel
name: Bukov, Marin
name: Ajoy, Ashok
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report the observation of long-lived Floquet prethermal discrete time crystalline (PDTC) order in a three-dimensional position-disordered lattice of interacting dipolar-coupled 13C nuclei in diamond at room temperature. We demonstrate a novel strategy of "two-frequency" driving, involving an interleaved application of slow and fast drives that simultaneously prethermalize the spins with an emergent quasi-conserved magnetization along the x-axis, while enabling continuous and highly resolved observation of their dynamic evolution when periodically kicked away from x. The PDTC order manifests itself in a robust period doubling response of this drive-induced quasi-conserved spin magnetization interchanging between x and -x; our experiments allow a unique means to study the formation and melting of PDTC order. We obtain movies of the time-crystalline response with a clarity and throughput orders of magnitude greater than previous experiments. Parametric control over the drive frequencies allows us to reach PDTC lifetimes up to 396 Floquet cycles which we measure in a single-shot experiment. Such rapid measurement enables detailed characterization of the entire PDTC phase diagram, rigidity and lifetime, informing on the role of prethermalization towards stabilizing the DTC response. The two-frequency drive approach represents the simplest generalization of DTCs to multi-frequency drives; it expands the toolkit for realizing and investigating long-lived non-equilibrium phases of matter stabilized by emergent quasi-conservation laws.
description: 8 pages, 5 figures. SI: 15 pages, 19 figures. 4 anc movie files (also available on Youtube)
The magnetic Bp star 36 Lyncis, II. A spectroscopic analysis of its co-rotating disk
Creators: name: Smith, M. A.
name: Wade, G. A.
name: Bohlender, D. A.
name: Bolton, C. T.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report on the physical properties of the disk-like structure of B8 IIIp star 36 Lyncis from line syntheses of phase-resolved, high resolution spectra obtained from the IUE archives and from newly obtained ground-based H$α$ spectra. This disk is highly inclined to the rotational axis and betrays its existence every half rotation cycle as one of two opposing sectors pass in front of the star. Although the disk absorption spectrum is at least ten times too weak to be visible in optical iron lines during these occultations, its properties can be readily examined in a large number of UV "iron curtain" lines because of their higher opacities. The analysis of the variations of the UV resonance lines brings out some interesting details about the radiative properties of the disks: (1) they are optically thick in the C IV and Si IV doublets, (2) the range of excitation of the UV resonance lines is larger at the primary occultation ($ϕ$ = 0.00) than at the secondary one, and (3) the {\bf relative strengths of the absorption peaks} for the two occultations varies substantially from line to line. We have modeled the absorptions of the UV C IV resonance and H$α$ absorptions by means of a simulated disk with opaque and translucent components. Our simulations suggest that a gap separates the star and the inner edge of the disk. The disk extends radially out to $\geq$10 R$_{*}$. The disk scale height perpendicular to the plane is $\approx$1R$_{*}$. However, the sector causing the primary occultation is about four times thicker than the opposite sector. The C IV scattering region extends to a larger height than the H$α$ region does, probably because it results from shock heating far from the cooler disk plane.
description: Accepted by Astronomy and Astrophysics
Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery.
Creators: name: Avnish Patel
name: Perrin, Abigail J
name: Flynn, Helen R
name: Bisson, Claudine
name: Withers-Martinez, Chrislaine
name: Treeck, Moritz
name: Flueck, Christian
name: Nicastro, Giuseppe
name: Martin, Stephen R
name: Ramos, Andres
name: Gilberger, Tim W
name: Snijders, Ambrosius P
name: Blackman, Michael J
name: Baker, David A
Publisher: name: The Francis Crick Institute
Year: 2020
Subjects: subject: Model organisms
subject: Biochemistry & Proteomics
subject: Structural Biology & Biophysics
subject: Cell Biology
subject: Chemical Biology & High Throughput
subject: Infectious Disease
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational & Systems Biology

description: Cyclic AMP (cAMP) is an important signalling molecule across evolution, but its role in malaria parasites is poorly understood. We have investigated the role of cAMP in asexual blood stage development of Plasmodium falciparum through conditional disruption of adenylyl cyclase beta (ACβ) and its downstream effector, cAMP-dependent protein kinase (PKA). We show that both production of cAMP and activity of PKA are critical for erythrocyte invasion, whilst key developmental steps that precede invasion still take place in the absence of cAMP-dependent signalling. We also show that another parasite protein with putative cyclic nucleotide binding sites, Plasmodium falciparum EPAC (PfEpac), does not play an essential role in blood stages. We identify and quantify numerous sites, phosphorylation of which is dependent on cAMP signalling, and we provide mechanistic insight as to how cAMP-dependent phosphorylation of the cytoplasmic domain of the essential invasion adhesin apical membrane antigen 1 (AMA1) regulates erythrocyte invasion.
Memorandum Regarding Export Import and PL 480 Credits
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1965
Subjects: Box 232 Folder 4
Box 232 Folder 04
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Memorandum for the President from Bator concerning the Yugoslav request for easing of export import and PL 480 credits for their aims to liberalize their economy.
Bomber Command logbook
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: I have a Bomber Command logbook and photos. Much of the information came via a gunner colleague, Jack Watson, after my father died. They were part of the Lancaster bomber crew. Both Jack and Bill were awarded several medals of recognition.Stories were told about sorties where other crews did not return. Most of the stories that were shared were humorous, demonstrating laughter in adversity.
Baryon Antibaryon Nonets
Creators: name: Yuan, C. Z.
name: Mo, X. H.
name: Wang, P.
Publisher: name: arXiv
Year: 2005
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The baryon-antibaryon SU(3) nonets are proposed as a scheme to classify the increased number of experimentally observed enhancements near the baryon antibaryon mass threshold. The scheme is similar to the Fermi-Yang-Sakata model, which was put forth about fifty years ago in explaining the mesons observed at that time. According to the present scheme, many new baryon-antibaryon bound states are predicted, and their possible productions in quarkonium decays and B decays are suggested for experimental search.
description: 5 pages, 1 figure
Tsallis and Kaniadakis statistics from a point of view of the holographic equipartition law
Creators: name: Abreu, Everton M. C.
name: Neto, Jorge Ananias
name: Mendes, Albert C. R.
name: Bonilla, Alexander
Publisher: name: arXiv
Year: 2017
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this work, we have illustrated the difference between both Tsallis and Kaniadakis entropies through cosmological models obtained from the formalism proposed by Padmanabhan, which is called holographic equipartition law. Similarly to the formalism proposed by Komatsu, we have obtained an extra driving constant term in the Friedmann equation if we deform the Tsallis entropy by Kaniadakis' formalism. We have considered initially Tsallis entropy as the Black Hole (BH) area entropy. This constant term may lead the universe to be in an accelerated mode. On the other hand, if we start with the Kaniadakis entropy as the BH area entropy and then by modifying the Kappa expression by Tsallis' formalism, the same constant, which shows that the universe have an acceleration is obtained. In an opposite limit, no driving inflation term of the early universe was derived from both deformations.
description: 8 pages, preprint format. Final version to appear in Europhysics Letters
Lotus jacobaeus Linnaeus 1753
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Lotus
Lotus jacobaeus

description: Lotus jacobaeus Linnaeus, Species Plantarum 2: 775. 1753.
"Habitat in Insula S. Jacobi." RCN: 5694.
 Lectotype (Wijnands, Bot. Commelins: 165. 1983): Herb. Clifford: 372, Lotus 7 (BM-000646728).
 Current name: Lotus jacobaeus L. (Fabaceae: Faboideae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 642, DOI: 10.5281/zenodo.291971
Note Regarding Proposal and Attached Memorandum
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1965
Subjects: Box 232 Folder 5
Box 232 Folder 05
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Note from Barr to Bundy concerning impact of support for Yugoslav package on financials and statistics.
Gopakumar-Vafa type invariants of holomorphic symplectic 4-folds
Creators: name: Cao, Yalong
name: Oberdieck, Georg
name: Toda, Yukinobu
Publisher: name: arXiv
Year: 2022
Subjects: subject: Algebraic Geometry (math.AG)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Using reduced Gromov-Witten theory, we define new invariants which capture the enumerative geometry of curves on holomorphic symplectic 4-folds. The invariants are analogous to the BPS counts of Gopakumar and Vafa for Calabi-Yau 3-folds, Klemm and Pandharipande for Calabi-Yau 4-folds, Pandharipande and Zinger for Calabi-Yau 5-folds.
 We conjecture that our invariants are integers and give a sheaf-theoretic interpretation in terms of reduced $4$-dimensional Donaldson-Thomas invariants of one-dimensional stable sheaves. We check our conjectures for the product of two $K3$ surfaces and for the cotangent bundle of $\mathbb{P}^2$. Modulo the conjectural holomorphic anomaly equation, we compute our invariants also for the Hilbert scheme of two points on a $K3$ surface. This yields a conjectural formula for the number of isolated genus $2$ curves of minimal degree on a very general hyperkähler $4$-fold of $K3^{[2]}$-type. The formula may be viewed as a $4$-dimensional analogue of the classical Yau-Zaslow formula concerning counts of rational curves on $K3$ surfaces.
 In the course of our computations, we also derive a new closed formula for the Fujiki constants of the Chern classes of tangent bundles of both Hilbert schemes of points on $K3$ surfaces and generalized Kummer varieties.
description: 53 pages
Structure-Preserving Image Super-resolution via Contextualized Multi-task Learning
Creators: name: Shi, Yukai
name: Wang, Keze
name: Chen, Chongyu
name: Xu, Li
name: Lin, Liang
Publisher: name: arXiv
Year: 2017
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Single image super resolution (SR), which refers to reconstruct a higher-resolution (HR) image from the observed low-resolution (LR) image, has received substantial attention due to its tremendous application potentials. Despite the breakthroughs of recently proposed SR methods using convolutional neural networks (CNNs), their generated results usually lack of preserving structural (high-frequency) details. In this paper, regarding global boundary context and residual context as complimentary information for enhancing structural details in image restoration, we develop a contextualized multi-task learning framework to address the SR problem. Specifically, our method first extracts convolutional features from the input LR image and applies one deconvolutional module to interpolate the LR feature maps in a content-adaptive way. Then, the resulting feature maps are fed into two branched sub-networks. During the neural network training, one sub-network outputs salient image boundaries and the HR image, and the other sub-network outputs the local residual map, i.e., the residual difference between the generated HR image and ground-truth image. On several standard benchmarks (i.e., Set5, Set14 and BSD200), our extensive evaluations demonstrate the effectiveness of our SR method on achieving both higher restoration quality and computational efficiency compared with several state-of-the-art SR approaches. The source code and some SR results can be found at: http://hcp.sysu.edu.cn/structure-preserving-image-super-resolution/
description: To appear in Transactions on Multimedia 2017
Interpretable Predictions of Tree-based Ensembles via Actionable Feature Tweaking
Creators: name: Tolomei, Gabriele
name: Silvestri, Fabrizio
name: Haines, Andrew
name: Lalmas, Mounia
Publisher: name: arXiv
Year: 2017
Subjects: subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: I.2.0; I.5.1
subject: 68T01

description: Machine-learned models are often described as "black boxes". In many real-world applications however, models may have to sacrifice predictive power in favour of human-interpretability. When this is the case, feature engineering becomes a crucial task, which requires significant and time-consuming human effort. Whilst some features are inherently static, representing properties that cannot be influenced (e.g., the age of an individual), others capture characteristics that could be adjusted (e.g., the daily amount of carbohydrates taken). Nonetheless, once a model is learned from the data, each prediction it makes on new instances is irreversible - assuming every instance to be a static point located in the chosen feature space. There are many circumstances however where it is important to understand (i) why a model outputs a certain prediction on a given instance, (ii) which adjustable features of that instance should be modified, and finally (iii) how to alter such a prediction when the mutated instance is input back to the model. In this paper, we present a technique that exploits the internals of a tree-based ensemble classifier to offer recommendations for transforming true negative instances into positively predicted ones. We demonstrate the validity of our approach using an online advertising application. First, we design a Random Forest classifier that effectively separates between two types of ads: low (negative) and high (positive) quality ads (instances). Then, we introduce an algorithm that provides recommendations that aim to transform a low quality ad (negative instance) into a high quality one (positive instance). Finally, we evaluate our approach on a subset of the active inventory of a large ad network, Yahoo Gemini.
description: 10 pages, KDD 2017
Astrophysical Sources of High Energy Neutrinos in the IceCube Era
Creators: name: Meszaros, P.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: High energy neutrino astrophysics has come of age with the discovery by IceCube of neutrinos in the TeV to PeV energy range attributable to extragalactic sources at cosmological distances. At such energies, astrophysical neutrinos must have their origin in cosmic ray interactions, providing information about the sources of high energy cosmic rays, as well as leading to the co-production of high energy gamma-rays. The intimate link with these latter two independently observed types of radiation provides important tools in the search for identifying and understanding the nature of their astrophysical sources. These neutrinons can provide important constraints about the cosmic ray acceleration process, and since they travel essentially unimpeded they can probe our Universe out to the farthest cosmological distances.
description: 26 pages, 8 figures; accepted in Annual Review of Nuclear and Particle Science; to appear in vol. 67 (2017)
The electrothermal conductance and heat capacity of black phosphorus
Creators: name: Sengupta, Parijat
name: Das, Saptarshi
name: Shi, Junxia
Publisher: name: arXiv
Year: 2017
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We study a thermal gradient induced current $\left(I_{th}\right)$ flow in potassium-doped two-dimensional anisotropic black phosphorus (BP) with semi-Dirac dispersion. The prototype device is a BP channel clamped between two contacts maintained at unequal temperatures. The choice of BP lies in the predicted efficient thermolectric behaviour. A temperature-induced difference in the Fermi levels of the two contacts drives the current (typified by the electro-thermal conductance) which we calculate using the Landauer transport equation. The current shows an initial rise when the device is operated at lower temperatures. The rise stalls at progressively higher temperatures and $I_{th}$ acquires a plateau-like flat profile indicating a competing effect between a larger number of transmission modes and a corresponding drop in the Fermi level difference between the contacts. The current is computed for both \textit{n}- and \textit{p}-type BP and the difference thereof is attributed to the particle-hole asymmetry. The utility of such calculations lie in conversion of the heat production and an attendant temperature gradient in miniaturized devices to useful electric power and a possible realization of solid-state Peltier cooling. Unlike the flow of $I_{th}$ that removes heat, the ability of a material to maintain a steady temperature is reflected in its heat capacity which is formulated in this work for BP via a Sommerfeld expansion. In the concluding part, we draw a microscopic connection between the two seemingly disparate processes of heat removal and absorption by pinning down their origin to the underlying density of states. Finally, a qualitative analysis of a Carnot-like efficiency of the considered thermoelectric engine is performed drawing upon the previous results on thermal current and heat capacity.
description: 9 pages, 7 figures. An amended version of this manuscript has been published in Journal of Chemical Physics
Active Random Walks in One and Two Dimensions
Creators: name: Jose, Stephy
name: Mandal, Dipanjan
name: Barma, Mustansir
name: Ramola, Kabir
Publisher: name: arXiv
Year: 2022
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We investigate active lattice walks: biased continuous time random walks which perform orientational diffusion between lattice directions in one and two spatial dimensions. We study the occupation probability of an arbitrary site on the lattice in one and two dimensions, and derive exact results in the continuum limit. Next, we compute the large deviation free energy function in both one and two dimensions, which we use to compute the moments and the cumulants of the displacements exactly at late times. Our exact results demonstrate that the cross-correlations between the motion in the $x$ and $y$ directions in two dimensions persist in the large deviation function. We also demonstrate that the large deviation function of an active particle with diffusion displays two regimes, with differing diffusive behaviors. We verify our analytic results with kinetic Monte Carlo simulations of an active lattice walker in one and two dimensions.
description: 17 pages, 11 figures, +Supplemental Material
An Activity-Based Quality Model for Maintainability
Creators: name: Deissenboeck, Florian
name: Wagner, Stefan
name: Pizka, Markus
name: Teuchert, Stefan
name: Girard, Jean-François
Publisher: name: arXiv
Year: 2017
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Maintainability is a key quality attribute of successful software systems. However, its management in practice is still problematic. Currently, there is no comprehensive basis for assessing and improving the maintainability of software systems. Quality models have been proposed to solve this problem. Nevertheless, existing approaches do not explicitly take into account the maintenance activities, that largely determine the software maintenance effort. This paper proposes a 2-dimensional model of maintainability that explicitly associates system properties with the activities carried out during maintenance. The separation of activities and properties facilitates the identification of sound quality criteria and allows to reason about their interdependencies. This transforms the quality model into a structured and comprehensive quality knowledge base that is usable in industrial project environments. For example, review guidelines can be generated from it. The model is based on an explicit quality metamodel that supports its systematic construction and fosters preciseness as well as completeness. An industrial case study demonstrates the applicability of the model for the evaluation of the maintainability of Matlab Simulink models that are frequently used in model-based development of embedded systems.
description: 11 pages, 6 figures
Bubble Lattices I: Structure
Creators: name: McConville, Thomas
name: Mühle, Henri
Publisher: name: arXiv
Year: 2022
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 06A07, 06D75, 05A05

description: C. Greene introduced the shuffle lattice as an idealized model for DNA mutation and discovered remarkable combinatorial and enumerative properties of this structure. We attempt an explanation of these properties from a lattice-theoretic point of view. To that end, we introduce and study an order extension of the shuffle lattice, the bubble lattice. We characterize the bubble lattice both locally (via certain transformations of shuffle words) and globally (using a notion of inversion set). We then prove that the bubble lattice is extremal and constructable by interval doublings. Lastly, we prove that our bubble lattice is a generalization of the Hochschild lattice studied earlier by Chapoton, Combe and the second author.
description: 24 pages, 8 figures. Comments are welcome
Impact of neuronal heterogeneity on correlated colored noise-induced synchronization.
Creators: name: Pengcheng  Zhou
name: Burton, Shawn D.
name: Urban, Nathan
name: G Bard  Ermentrout
Publisher: name: Carnegie Mellon University
Year: 2013
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Synchronization plays an important role in neural signal processing and transmission. Many hypotheses have been proposed to explain the origin of neural synchronization. In recent years, correlated noise-induced synchronization has received support from many theoretical and experimental studies. However, many of these prior studies have assumed that neurons have identical biophysical properties and that their inputs are well modeled by white noise. In this context, we use colored noise to induce synchronization between oscillators with heterogeneity in both phase-response curves and frequencies. In the low noise limit, we derive novel analytical theory showing that the time constant of colored noise influences correlated noise-induced synchronization and that oscillator heterogeneity can limit synchronization. Surprisingly, however, heterogeneous oscillators may synchronize better than homogeneous oscillators given low input correlations. We also find resonance of oscillator synchronization to colored noise inputs when firing frequencies diverge. Collectively, these results prove robust for both relatively high noise regimes and when applied to biophysically realistic spiking neuron models, and further match experimental recordings from acute brain slices.
Diary extracts from William Pearson
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Thomas has brought in a 1940 diary belonging to his great-grandfather, William Pearson. The diary came into his possession after the death of his grandfather. The front of the diary was bought from A B Murray, a printer and stationer in Wigan. Pearson worked on the railways, joined the BEF, and went to Brest in France. One of the first entries in the diary mentions a Captain Tucker being killed on 4 January. It seems he realized when he was out there it was significant as he recorded things in 1940 but stopped after he was evacuated.
Telegram Regarding Jarring Mission
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1968
Subjects: Box 232 Folder 9
Box 232 Folder 09
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Telegram detailing call from Ambassador crnobrnja concerning status of Jarring mission and support of Yugoslavia.
Coordinate representation for non Hermitian position and momentum operators
Creators: name: Bagarello, F.
name: Gargano, F.
name: Spagnolo, S.
name: Triolo, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper we undertake an analysis of the eigenstates of two non self-adjoint operators $\hat q$ and $\hat p$ similar, in a suitable sense, to the self-adjoint position and momentum operators $\hat q_0$ and $\hat p_0$ usually adopted in ordinary quantum mechanics. In particular we discuss conditions for these eigenstates to be {\em biorthogonal distributions}, and we discuss few of their properties. We illustrate our results with two examples, one in which the similarity map between the self-adjoint and the non self-adjoint is bounded, with bounded inverse, and the other in which this is not true. We also briefly propose an alternative strategy to deal with $\hat q$ and $\hat p$, based on the so-called {\em quasi *-algebras}.
description: Accepted in Proceedings of the Royal Society A
On the chiral algebra of Argyres-Douglas theories and S-duality
Creators: name: Choi, Jaewang
name: Nishinaka, Takahiro
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the two-dimensional chiral algebra associated with the simplest Argyres-Douglas type theory with an exactly marginal coupling, i.e., the $(A_3,A_3)$ theory. Near a cusp in the space of the exactly marginal deformations (i.e., the conformal manifold), the theory is well-described by the $SU(2)$ gauge theory coupled to isolated Argyres-Douglas theories and a fundamental hypermultiplet. In this sense, the $(A_3,A_3)$ theory is an Argyres-Douglas version of the $\mathcal{N}=2$ $SU(2)$ conformal QCD. By studying its Higgs branch and Schur index, we identify the minimal possible set of chiral algebra generators for the $(A_3,A_3)$ theory, and show that there is a unique set of closed OPEs among these generators. The resulting OPEs are consistent with the Schur index, Higgs branch chiral ring relations, and the BRST cohomology conjecture. We then show that the automorphism group of the chiral algebra we constructed contains a discrete group $G$ with an $S_3$ subgroup and a homomorphism $G\to S_4 \times {\bf Z}_2$. This result is consistent with the S-duality of the $(A_3,A_3)$ theory.
description: 25 pages, 2 figures
Memorandum Regarding Dedijer Case
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1968
Subjects: Box 232 Folder 9
Box 232 Folder 09
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Memorandum from Davis to Rostow concerning refusal of Dedijer visa.
Impact of migration and fitness on the stability of lethal t-haplotype polymorphism in Mus musculus: a computer study.
Creators: name: Durand, Dannie
name: Ardlie, Kristin
name: Buttel, Linda
name: Levin, Simon A.
name: Silver, Lee M.
Publisher: name: Carnegie Mellon University
Year: 1997
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The t-haplotype is a chromosomal region in Mus musculus characterized by meiotic drive such that heterozygous males transmit t-bearing chromosomes to roughly 90% of their offspring. Most naturally occurring t-haplotypes express a recessive embryonic lethality, preventing fixation of the t-haplotype. Surprisingly, the t-haplotype occurs in nature as a persistent, low-frequency polymorphism. Early modeling studies led LEWONTIN to hypothesize that this low level polymorphism results from a balance between genetic drift in small demes and interdemic migration. Here, we show that while combination of deme size and migration rate that predict natural t-haplotype frequencies exist, the range of such values is too narrow to be biologically plausible, suggesting that small deme size and interdemic migration alone do not explain the observed t-haplotype frequencies. In response, we tested other factors that might explain the observed t-polymorphism. Two led to biologically plausible models: substantially reduced heterozygous fitness and reduced meiotic drive. This raises the question whether these phenomena occur in nature. Our data suggest an alternative explanation: there is no stable, low-level t-polymorphism. Rather wild populations are in one of two stable states characterized by extinction of the t-haplotype and a high t-haplotype frequency, respectively, or in transition between the two.
The magnetic Bp star 36 Lyncis, I. Magnetic and photospheric properties
Creators: name: Wade, G. A.
name: Smith, M. A.
name: Bohlender, D. A.
name: Ryabchikova, T. A.
name: Bolton, C. T.
name: Lueftinger, T.
name: Landstreet, J. D.
name: Petit, P.
name: Strasser, S.
name: Blake, M.
name: Hill, G. M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: This paper reports the photospheric, magnetic and circumstellar gas characteristics of the magnetic B8p star 36 Lyncis (HD 79158). Using archival data and new polarised and unpolarised high-resolution spectra, we redetermine the basic physical properties, the rotational period and the geometry of the magnetic field, and the photospheric abundances of various elements.}{Based on magnetic and spectroscopic measurements, we infer an improved rotational period of $3.83475\pm 0.00002$ d. We determine a current epoch of the longitudinal magnetic field positive extremum (HJD 2452246.033), and provide constraints on the geometry of the dipole magnetic field ($i\geq 56\degr$, $3210 {\rm G}\leq B_{\rm d}\leq 3930$ G, $β$ unconstrained). We redetermine the effective temperature and surface gravity using the optical and UV energy distributions, optical photometry and Balmer line profiles ($T_{\rm eff}=13300\pm 300$ K, $\log g=3.7-4.2$), and based on the Hipparcos parallax we redetermine the luminosity, mass, radius and true rotational speed ($L=2.54\pm 0.16 L_\odot, M=4.0\pm 0.2 M_\odot, R=3.4\pm 0.7 R_\odot, v_{\rm eq}=45-61.5$ \kms). We measure photospheric abundances for 21 elements using optical and UV spectra, and constrain the presence of vertical stratification of these elements. We perform preliminary Doppler Imaging of the surface distribution of Fe, finding that Fe is distributed in a patchy belt near the rotational equator. Most remarkably, we confirm strong variations of the H$α$ line core which we interpret as due to occultations of the star by magnetically-confined circumstellar gas.
description: Accepted by Astronomy and Astrophysics
Telegram Regarding Visa
Creators: name: United States. Department Of State
Publisher: name: The University of Texas at Austin
Year: 1968
Subjects: Box 232 Folder 9
Box 232 Folder 09
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Telegram from Rostow to the President concerning visa for Vladimir and his comments concerning America and Vietnam,
Hessian-based adaptive sparse quadrature for infinite-dimensional Bayesian inverse problems
Creators: name: Chen, Peng
name: Villa, Umberto
name: Ghattas, Omar
Publisher: name: arXiv
Year: 2017
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: In this work we propose and analyze a Hessian-based adaptive sparse quadrature to compute infinite-dimensional integrals with respect to the posterior distribution in the context of Bayesian inverse problems with Gaussian prior. Due to the concentration of the posterior distribution in the domain of the prior distribution, a prior-based parametrization and sparse quadrature may fail to capture the posterior distribution and lead to erroneous evaluation results. By using a parametrization based on the Hessian of the negative log-posterior, the adaptive sparse quadrature can effectively allocate the quadrature points according to the posterior distribution. A dimension-independent convergence rate of the proposed method is established under certain assumptions on the Gaussian prior and the integrands. Dimension-independent and faster convergence than $O(N^{-1/2})$ is demonstrated for a linear as well as a nonlinear inverse problem whose posterior distribution can be effectively approximated by a Gaussian distribution at the MAP point.
Tetragonolobus maritimus Roth 1989
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Tetragonolobus
Tetragonolobus maritimus

description: Lotus maritimus Linnaeus, Species Plantarum 2: 773. 1753.
"Habitat in Europae maritimis." RCN: 5684.
 Lectotype (Domínguez & Galiano in Lagascalia 8: 197. 1979): Herb. Linn. No. 931.1 (LINN).
 Current name: Tetragonolobus maritimus (L.) Roth (Fabaceae: Faboideae).
 Note: Stearn (in Biol. J. Linn. Soc. 5: 11. 1973), in an account of Linnaeus’ Öland and Gotland journey of 1741, treated Grankulla in Öland as the restricted type locality, and noted the existence of 931.1 (LINN). In his paper, he attributed restricted type localities irrespective of whether any material existed in LINN and, where specimens do exist, he does not refer to any of them as type specimens. The collection subsequently designated as the type shows no annotation associating it with Öland.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 642, DOI: 10.5281/zenodo.291971
MCRI Open Access Policy
Creators: name: Phillipson, Nitya
Publisher: name: Murdoch Childrens Research Institute
Year: 2024
Subjects: Uncategorised

description: (From Overview and Purpose)
The purpose of this policy is to facilitate compliance with the Open Access requirements set by MCRI’s research funders. The policy is aimed at promoting the dissemination of a wide range of research outputs, including journal articles, metadata associated with research data and – where possible - research datasets, to foster transparency, collaboration, and global knowledge sharing.
Telegram Regarding Logistics and Press Campaign
Creators: name: United States. Embassy (Belgrade)
Publisher: name: The University of Texas at Austin
Year: 1967
Subjects: Box 232 Folder 9
Box 232 Folder 09
Yugoslavia -- Politics and government -- 1945-1980
Yugoslavia -- Foreign relations -- 1945-1980 -- Soviet Union

description: Telegram concerning logistics of Nikezic appointment with President and launch of Yugoslav world-wide ocnsulting campaign.
Immune cells detection of the in vivo rejecting heart in USPIO-enhanced magnetic resonance imaging.
Creators: name: Hsun-Hsien  Chang
name: Moura, José M. F.
name: Yi-Jen L. Wu
name: Ho, Chien
Publisher: name: Carnegie Mellon University
Year: 2006
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Contrast-enhanced magnetic resonance imaging (MRI) is useful to study the infiltration of immune cells, in particular macrophages. Contrast agents, for example ultra-small superparamagnetic iron oxide (USPIO) particles, administered intravenously into the blood stream will be engulfed by macrophages circulating in the circulation system. When a transplanted heart rejects, macrophages and other immune cells will infiltrate the rejecting tissue. Imaged by T*2 weighted MRI, USPIO-labeled macrophages will display dark pixel intensities. Detecting the presence of USPIO particles in the images facilitates the study of heart rejection. We cast the problem of detecting the presence of USPIO-labeled myocardium in the framework of spectral graph theory, and treat our decision function as a level set function on the image. The pixels with positive level set values correspond to the presence of immune cells, and negative to the absence. When the image is modeled by a graph, the spectral analysis of the graph Laplacian provides a basis to represent the level set function. We develop from the Cheeger constant of the graph an objective functional of the level set function. The minimization of the objective leads to the optimal level set function. Experimental results suggest the feasibility of our approach in the study of rejecting hearts.
Indigofera mauritanica Thunb.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Fabales
Fabaceae
Indigofera
Indigofera mauritanica

description: Lotus mauritanicus Linnaeus, Systema Naturae, ed. 10, 2: 1179. 1759.
["Habitat ad Cap. b. spei."] Sp. Pl., ed. 2, 2: 1091 (1763). RCN: 5289.
 Basionym of: Ononis mauritanica. (L.) L. (1771).
 Lectotype (Schrire inTurland & Jarvis in Taxon 46: 475. 1997): Herb. Linn. No. 931.34 (LINN).
 Current name: Indigofera mauritanica (L.) Thunb. (Fabaceae: Faboideae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part L), pp. 610-650 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on pages 642-643, DOI: 10.5281/zenodo.291971
A deep near-infrared spectroscopic survey of the Scutum-Crux arm for Wolf-Rayet stars
Creators: name: Rosslowe, C K
name: Crowther, Paul A
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present an NTT/SOFI spectroscopic survey of infrared selected Wolf-Rayet candidates in the Scutum-Crux spiral arm (298 < l < 340, |b| < 0.5). We obtained near-IR spectra of 127 candidates, revealing 17 Wolf-Rayet stars - a ~13% success rate - of which 16 are newly identified here. The majority of the new Wolf-Rayet stars are classified as narrow-lined WN5-7 stars, with 2 broad-lined WN4-6 stars and 3 WC6-8 stars. The new stars, with distances estimated from previous absolute magnitude calibrations, have no obvious association with the Scutum-Crux arm. Refined near-infrared (YHJK) classification criteria based on over a hundred Galactic and Magellanic Cloud WR stars, providing diagnostics for hydrogen in WN stars, plus the identification of WO stars and intermediate WN/C stars. Finally, we find that only a quarter of WR stars in the survey region are associated with star clusters and/or HII regions, with similar statistics found for Luminous Blue Variables in the Milky Way. The relative isolation of evolved massive stars is discussed, together with the significance of the co-location of LBVs and WR stars in young star clusters.
description: 19 pages, accepted for MNRAS, plus 13 pages of supplementary information including near-IR spectral classification of WR stars
Immobilization of aprotinin to fibrinogen as a novel method for controlling degradation of fibrin gels.
Creators: name: Smith, Jason
name: Chen, Andrew
name: Ernst, Lauren A.
name: Waggoner, Alan
name: Campbell, Phil G.
Publisher: name: Carnegie Mellon University
Year: 2007
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The goal of this work was to demonstrate that aprotinin conjugated to fibrinogen could (1) maintain its function and (2) control fibrin degradation. Using the chick chorioallantoic membrane (CAM) assay, we found that blood vessels did not directly invade fibrin constructs containing immobilized fibroblast growth factor-2. Because the fibrin quickly degraded within approximately 5 days, we hypothesized that controlling fibrinolysis may improve direct blood vessel invasion. Aprotinin, a protease inhibitor typically added to slow fibrinolysis, is a small protein and can diffuse out of the gel resulting in the loss of fibrinolysis protection. Therefore, using a novel synthesis strategy, aprotinin and a fluorescent reporter, Cy3, were chemically conjugated to fibrinogen. In vitro microplate absorbance assays showed that the conjugated aprotinin was able to inhibit plasmin-mediated fibrin degradation and that its activity was comparable to equimolar levels of soluble, nonconjugated aprotinin. Additionally, we found that fibrinolysis rates could be tuned by varying the level of conjugated aprotinin within the gel. The conjugated aprotinin also demonstrated functionality in vivo. In the chick CAM assay, fibrin gels containing conjugated aprotinin were approximately 5 times larger than gels containing soluble aprotinin after 4 days. Also, in support of our hypothesis, we found that immobilized aprotinin within fibrin gels demonstrated substantial blood vessel invasion.