cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Effects of Resistance Training on Tobacco-Related CVD Risk
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Poor vascular function and future risk of cardiovascular disease all hallmarks of tobacco smoking, and many young adults who smoke cigarettes already have poor vascular function. Finding therapies to facilitate smoking cessation and to modify tobacco related risk factors for future cardiovascular disease in imperative. This project will determine the role of a weight training program in isolation or conjunction with standard smoking cessation therapy via nicotine replacement plus counseling on the function of blood vessels, how much oxidation is in the body, inflammation in the body and how well the body handles glucose young men and women smokers. The main objectives of this study are to determine the effects of a weight training program either by itself or together with nicotine replacement therapy and counseling on the function of blood vessels, oxidation in the body, inflammation in the body and the action of insulin. Blood vessel function, oxidative “free radicals”, inflammation in the body, insulin function, body composition will be measured. This project will be the first one to determine the effects of weight training by itself or together with conventional smoking cessation interventions on these risk factors for cardiovascular disease. If the hypotheses are supported, greater emphasis can be placed on the pivotal role of weight training as therapeutic intervention to improve the blood vessel function and/or facilitate smoking cessation in young adult men and women smokers.
Hydrogen interaction with Al(111) and Ti-doped Al(111)surfaces for H storage applications
Creators: name: Schaefer, Stefan P.
Publisher: name: No Publisher Supplied
Year: 2007

description: Complex metal hydrides are promising candidates for hydrogen storage applications.Most of these materials consist of aluminum mixed with other elements. It was foundthat titanium doping allows their use in a convenient temperature and pressure range.Therefore the key process is the dissociation of molecular hydrogen at a Ti catalyst on the surface. Preliminary studies with pure and titanium-doped aluminum surfaces areundertaken to gain a basic understanding of the hydrogen adsorption mechanism.The interaction of hydrogen with an Al(111) surface was studied using Infrared ReflectionAbsorption Spectroscopy (IRRAS) under Ultra High Vacuum (UHV) conditions. Hereby the formation of aluminum hydrides (alanes) in different sizes was observed depending on the hydrogen coverage of the surface. The growth of larger alanes is favored at higher H exposures. Different measurements were carried out for temperatures of 93, 180 and 259K and it was found that larger alanes form at higher temperatures.In another step of the experiment an Al surface was doped with titanium atoms emitted from a home-built Ti-source. Ti structures with a thickness of less than one monolayer (ML) were grown at 105K and a Ti film of around one ML was deposited at room temperature. The deposition rate was determined with a quartz crystal monitor and the deposition on the surface could be verified by Auger Electron Spectroscopy (AES). Low Energy Electron Diffraction (LEED) patterns were recorded before and after different Ti-depositions and were always showing the typical hexagonal symmetry for the closed packed (111) surface of the fcc Al crystal.To compare the vibrational modes of alanes forming on Al(111) surfaces with the ones of solid state AlH3 Fourier Transform Infrared Spectroscopy (FTIR) was performed in a different setup using a high vacuum. No matches of the frequencies could be found but the decomposition of AlH3 to Al and H could be observed at temperatures higher than 170°C.
Quantum walks and ground state problems
Creators: name: Richter, Peter C. (Peter Courtland)
Publisher: name: No Publisher Supplied
Year: 2007

description: Since the appearance of Shor's factoring algorithm in 1994, the search for novel quantum computer algorithms has proved surprisingly difficult.  Two design approaches that have yielded some progress are quantum walks and adiabatic computing.  The former has been shown to speed up algorithms whose complexity is related to the classical hitting time of a symmetric Markov chain, and there is evidence that the latter speeds up simulated annealing algorithms for computing ground states of classical Hamiltonians.In this thesis, we look into the possibility of obtaining a quantum speedup for the mixing time of a symmetric Markov chain.  We prove that by subjecting a quantum walk to a small amount of decoherence (typically the adversary of a quantum computer), it can be forced to mix to the correct stationary distribution, often considerably faster than its classical counterpart.  A more general theorem to this effect would imply quantum speedups for a variety of approximation algorithms for #P-complete problems.We conclude with some observations on adiabatic computing -- a time-dependent generalization of the quantum walk framework -- and the problem of estimating the ground state energy of a quantum Hamiltonian with local spin interactions.
Dietary lycopene modulates prostate cancer biomarker genes in androgen-independent human prostate cancer (PC-3) cell line
Creators: name: Reyes, Marynell D.
Publisher: name: No Publisher Supplied
Year: 2007

description: In the United States prostate cancer is the most commonly diagnosed cancer and is the second leading cause of death from malignancies in men. Dietary components have been recently targeted in the prevention and treatment of cancer, in combination with existing medical treatments for prostate cancer. Lycopene is a fat soluble red-orange carotenoid primarily consumed in foods containing tomatoes and tomato-derived products including tomato sauce, tomato paste and ketchup, with relatively smaller amounts in dried apricots, watermelon and pink grapefruit. Our objective is to determine whether lycopene treatment modulates prostate cancer biomarker genes in hormone-refractory human prostate cancer (PC-3) cell lines using Oligo GEArray® DNA Microarray which contains 263 genes involved in the prognosis and diagnosis of prostate cancer. Cell viability experiments determined that 25µM lycopene was the highest non-toxic treatment dose and therefore was selected for further experiments.  Microarray image analysis demonstrated a decrease in the expression of transforming growth factor beta-2 (TGFβ-2), cyclin dependent kinase-9 (CDK-9), epidermal growth factor receptor (EGFR), B-cell lymphoma-2 (BCL-2), B-cell lymphoma-2 like 1 (BCL2L1), insulin-like growth factor 1 receptor (IGF1R), cyclin dependent kinase-7 (CDK-7), and breast cancer 1 (BRCA1) genes after the treatment of PC-3 cells with 25µM lycopene.   Percent down-regulation calculated for TGFβ-2, CDK-9, EGFR, BCL-2, BCL2L1, IGF1R, CDK-7, and BRCA1 genes was 79%, 68%, 59%, 54%, 52%, 48%, 43%, and 38%, respectively, in lycopene-treated  versus untreated samples.  The modulated expressions of EGFR, IGF1R, BRCA1, CDK-9, TGFβ-2, CDK-7, and BCL-2 genes were validated using  Real-Time Polymerase Chain Reaction (Real-Time PCR) and the results demonstarted a down-regulation of 72%, 61%, 56%, 56%, 44%, 34%, and 30%, respectively. Among all modulated prostate cancer biomarker genes, EGFR demonstrated the most consistent down-regulation in expression in our  microarray and Real-Time PCR analyses.  Protein expression analysis demonstrated that lycopene treatment also decreased  EGFR protein expression in lycopene-treated PC-3 cells by 36%. These results indicate that the treatment of PC-3 cells with lycopene consistently modulates several prostate cancer biomarker genes.  The present study clearly indicates that EGFR is down-regulated at the mRNA and protein levels after treatment with 25µM lycopene.  Therefore, the results suggest that lycopene may be beneficial in delaying or preventing the progression of prostate disease.
FUTURE OF DENTAL CARE: INTEGRATING AI, METAVERSE, AR/VR, TELEDENTISTRY, CAD & 3D PRINTING, BLOCKCHAIN AND CRISPR INNOVATIONS
Creators: name: Ritik Kashwani
name: Gurmeet Ahuja
name: Vishant Narula
name: Ajimol Theresa Jose
name: Vishal Kulkarni
name: Rinky Hajong
name: Soni Gupta
Publisher: name: Zenodo
Year: 2024
Subjects: Artificial Intelligence, Augmented Reality, Blockchain, CAD, CRISPR, Dental Technology, Diagnostics, Modern Dentistry, Patient Care, Treatment Planning, Teledentistry, 3D Printing, Virtual Reality.

description: Abstract

The rapid evolution of technology is profoundly transforming modern dentistry, offering enhanced diagnostic accuracy, optimized treatment plans, and improved patient outcomes. This paper investigates the integration of various cutting-edge technologies such as Artificial Intelligence (AI), Augmented Reality (AR), Virtual Reality (VR), Teledentistry, Computer-assisted Design (CAD), 3D Printing, Blockchain, and CRISPR in the dental field. AI applications are revolutionizing diagnostic processes, particularly in detecting dental caries, periodontitis, and planning orthodontic treatments. AR and VR are enhancing educational methodologies and clinical applications by providing immersive, real-time feedback and visualization, improving both student training and patient care. Teledentistry is breaking barriers to access, especially for underserved populations, by facilitating remote consultations and emphasizing preventive care. CAD and 3D Printing are streamlining the creation of dental prosthetics, making the process more efficient and precise. Blockchain technology ensures secure storage and sharing of patient records, enhancing data privacy and disaster victim identification. CRISPR, a groundbreaking genome-editing tool, holds promise for targeted treatments of oral diseases. The paper discusses the transformative potential of these technologies, highlighting current applications, challenges, and future directions in modern dentistry.
Preferential nucleation of cobalt nanoclusters on the faceted rhenium (12¯31) surface
Creators: name: Reyhan, Meral
Publisher: name: No Publisher Supplied
Year: 2007

description: We have studied the preferential nucleation of cobalt nanoclusters on oxidized faceted rhenium(12¯3 1) by means of Auger electron spectroscopy (AES), low energy electron diffraction (LEED), and scanning tunneling microscopy (STM).  Preferential nucleation means that the Co nanoclusters form at specific sites on the substrate.  In contrast to previous nanostructure studies of preferential nanocluster nucleation in metal on metal experiments, we use a surface that is both oxidized and faceted to form a nanotemplate.  It is shown that for cobalt coverage between 1.6 ML and 3 ML, preferential nucleation of cobalt nanoclusters occurs on this faceted surface.  It is also shown that by varying the parameters of cobalt coverage, facet width and annealing temperature, the cobalt nanocluster size can be varied.  The cobalt nanocluster system may prove to be a model system for future studies of different substrates and overlayers more relevant to catalytic reactions.
Filtering techniques for data streams
Creators: name: Rozenbaum, Irina
Publisher: name: No Publisher Supplied
Year: 2007

description: With the growth in popularity and complexity of streaming applications, there is a rising need for sophisticated analyses of massive high speed data generated by such applications. Such analyses often need to be performed in near real-time, using limited system resources. Under such conditions, it is very important to find an appropriate balance between the efficiency of processing and the accuracy of the produced results. A common technique is to filter the stream with suitable conditions so that the resulting data size is manageable, and the analyses are still accurate.The work presented by this thesis focuses on a number of complex filtering techniques that are of interest in data steam processing in general and in network traffic monitoring in particular. These techniques allow the analyst to define a filtering condition that is more appropriate for the particular query at hand than the simpler random uniform sampling.First, we propose a single operator which captures a common thread of evaluation of sampling queries and can be specialized to implement a wide variety of quite sophisticated stream sampling algorithms within an operational data stream management system and scale in performance to line speeds. Additionally, we propose a solution for flow sampling mechanism, which integrates the logic of flow aggregation as well as flow sampling into one procedure that works directly on IP traffic. Next, we introduce the notion of the inverse distribution for massive data streams, and present algorithms that draw a uniform sample from the inverse distribution in the presence of inserts and deletes to the stream; such a sample can be used for a variety of summarization and filtering/mining tasks.Another contribution of this thesis is the development of a filter join operator, which makes it feasible to evaluate a common type of join query that searches for records matching dynamic criteria on high speed data streams, in an efficient, stable and accurate manner. We also present analyses of query transformations which expose the filter join operator in conventional query join.Finally, we study the problem of matching regular expression that can span multiple data records in a data stream in the presence of stream quality problems, such as duplicates and out-of-order records; we present a number of algorithms that can match regular expressions over multiple data stream records without stream reassembly, by maintaining partial state of the data in the stream.The ideas presented in this thesis are motivated by actual practical problems that arise in data stream processing, and are further validated by the presented experimental studies.
Taractrocera maevius subsp. sagara Common Grass Dart
Creators: name: Bhowmik, Suman
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Hesperiidae
Taractrocera
Taractrocera maevius
Taractrocera maevius sagara (moore, [1866]) (common grass dart)

description: 13. Taractrocera maevius sagara (Moore, [1866]) (Common Grass Dart)
Remarks. On 12.viii.2015, on individual was recorded at Ganganagar Tea Garden (24°3’29” N & 92°16’42” E, ca. 49 m above msl.), North Tripura District while perching on a grass. This species is rare throughout the state.
Current known distribution. Pakistan, Bangladesh, Myanmar, India (Gujarat to Kerala; Madhya Pradesh; West Bengal; Jammu & Kashmir to Northeast India) (Van Gasse 2013; Varshney & Smetacek 2015).
description: Published as part of Bhowmik, Suman, 2021, Fifty-one new additions to the butterfly (Lepidoptera: Rhopalocera) fauna of Tripura, North-east India, pp. 35-60 in Revista Chilena de Entomología (Rev. Chil. Entomol.) (Rev. Chil. Entomol.) 47 (1) on page 43, DOI: 10.35249/rche.47.1.21.04, http://zenodo.org/record/10950112
States, housing and innovation: the role of state housing finance agencies
Creators: name: Scally, Corianne P.
Publisher: name: No Publisher Supplied
Year: 2007

description: The gradual withdrawal of federal leadership in affordable housing has required states to step into an ever-widening gap in housing policy and finance. This has increased the influence of state housing finance agencies (HFAs), the only state-level housing agency that all fifty states have in common. This research expands current understanding of these agencies by asking: 1) how have HFA roles in creating, adopting, and implementing state housing policy evolved over time, and 2) what factors promote or constrain their ability to innovate, and how? Assisted by theories of organizational innovation and state policy innovation, innovation within HFAs is linked to a series of internal, organizational factors and external, environmental determinants, as well as forces of diffusion. This research employed a mixed methodology, using both quantitative analysis of longitudinal time-series data and qualitative case studies. Results show that HFAs are filling substantially expanded roles in addition to their three historical functions as lender, administrator, and (re)developer of affordable housing. These include housing researcher and planner, coordinator of other state entities, educator, nonprofit capacity builder, and policymaker. An event history analysis of state adoption and HFA administration of a housing trust fund since 1985 revealed that environmental determinants are more important than influences from within the organization or from neighboring states in motivating innovation. In general, states with higher rates of new, single-family development, larger black populations, and a more liberal citizenry have a higher risk of adopting a HTF policy innovation. Finally, case studies of the Illinois Housing Development Authority and the New Jersey Housing and Mortgage Finance Agency indicated a variety of factors important in promoting or constraining HFA innovation in general, including public perception of a housing crisis, state housing policy context, political leadership, interest groups, resources, organizational structure, staff attitudes and retention, and national networks. These findings have important implications for state executives and legislators, HFAs, other state agencies, interest groups, and local governments, in order to create an environment more conducive to future state affordable housing policy innovation.
Protodasyapha (Curumyia) lugens
Creators: name: González, Christian R.
name: Elgueta, Mario
name: Krolow, Tiago K.
name: Henriques, Augusto L.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tabanidae
Protodasyapha
Protodasyapha lugens

description: Protodasyapha (Curumyia) lugens (Philippi, 1865).
Tabanus lugens Philippi, 1865: 719.
Tabanus obscuripennis Philippi, 1865: 722. Holotype. Female (no type specimens found in MNNC), Chile: Santiago. Hunter, 1901: 142 (cat.); Porter, 1902: 248 (Chile spp.); Kertész, 1908: 266 (cat.); Kröber, 1930e: 133 (diag., Mycteromyia); Kröber, 1934: 312 (cat.); Stuardo, 1946: 73 (cat.); Moucha, 1976: 22 (cat., Protodasyapha); Philip, 1968a: 11 (tax., Philippi’s types); Fairchild, 1971: 4 (cat., Protodasyapha).
Dasybasis tristis Bigot, 1892: 621. Syntypes. Three males (NHMUK), Chile. Kertész, 1900: 29 (cat.); Ricardo, 1904: 350 (NHMUK spp.); Porter, 1902: 246 (Chile spp.); Kertész, 1908: 209 (cat.); Surcouf, 1921: 41 (dist.); Kröber, 1930b: 169 (in key, Protodasyapha), 170 (redes.); Kröber, 1930e: 122 (in key, Protodasyapha); Kröber, 1934: 238 (cat., Protodasyapha); Fairchild, 1956: 30 (com.,? Protodasyapha); Chainey, 1990: 315 (NHMUK types).
Holotype. Female (destroyed, only scutum, legs and wings in MNNC). Type-locality: Chile, Santiago.
Distribution. Argentina: Provincia de Neuquén. Chile: Región de Coquimbo (Choapa); Región de Valparaíso (Los Andes); Región Metropolitana (Santiago); Región de O´Higgins (Cachapoal); Región del Maule (Curicó).
References. Schiner, 1868: 92 (com., Tabanus); Kertész, 1900: 58 (cat., Tabanus); Hunter, 1901: 141 (cat., Tabanus); Porter, 1902: 248 (Chile spp., Tabanus); Kertész, 1908: 256 (cat., Tabanus); Surcouf, 1921: 74 (dist., Tabanus); Kröber, 1930b: 169 (in key, redes.); Kröber, 1930e: 122 (in key); Kröber, 1934: 238 (cat.); Hack, 1953: 339 (descr. male); Coscarón, 1967b: 105 (Argentina spp.); Philip, 1968a: 11 (tax., Philippi’s types); Fairchild, 1971: 5 (cat., Veprius); Coscarón, 1976: 82–85 (redes., figs. 3A–I, 4A–J)); Moucha, 1976: 17 (cat., Veprius); Coscarón et al., 1979: 304 (com.); Coscarón & González, 1991: 127 (Chile spp.); Fairchild & Burger, 1994: 30 (cat.); Coscarón, 1998: 349 (list, dist.); Coscarón & Papavero, 2009a: 37 (female, figs. 9A–J), 38 (male, figs. 10A–I); Coscarón & Papavero, 2009b: 31 (cat.).
description: Published as part of González, Christian R., Elgueta, Mario, Krolow, Tiago K. & Henriques, Augusto L., 2022, Catalog of the horse-flies (Diptera: Tabanidae) of Chile, pp. 201-257 in Zootaxa 5091 (2) on page 213, DOI: 10.11646/zootaxa.5091.2.1, http://zenodo.org/record/5843635
Coladenia agnioides Elwes & Edwards 1897
Creators: name: Bhowmik, Suman
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Hesperiidae
Coladenia
Coladenia agnioides

description: 14. Coladenia agnioides Elwes & Edwards, 1897 (Elwes’s Pied Flat)
Remarks. Two individuals were recorded at Betlingchhip (23°48’51” N & 92°15’33” E, ca. 827 m above msl.), on 26.viii.2019, near a roadside. Recently in October 2020 another individual was sighted at the same location. This species is very rare throughout the state.
Current known distribution. Nepal, Myanmar, India (Manipur, Nagaland, Sikkim) (Van Gasse 2013; Varshney & Smetacek 2015).
description: Published as part of Bhowmik, Suman, 2021, Fifty-one new additions to the butterfly (Lepidoptera: Rhopalocera) fauna of Tripura, North-east India, pp. 35-60 in Revista Chilena de Entomología (Rev. Chil. Entomol.) (Rev. Chil. Entomol.) 47 (1) on page 46, DOI: 10.35249/rche.47.1.21.04, http://zenodo.org/record/10950112
Protodasyapha Enderlein 1922
Creators: name: González, Christian R.
name: Elgueta, Mario
name: Krolow, Tiago K.
name: Henriques, Augusto L.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tabanidae
Protodasyapha

description: Subgenus Protodasyapha Enderlein, 1922: 337
References. Coscarón, 1976: 78 (com.); Coscarón & González, 1991: 134 (in key); Coscarón & Papavero, 1993: 15 (in key); Coscarón, 1998: 349 (list, dist.); Coscarón & Papavero, 2009a: 7 (in key).
description: Published as part of González, Christian R., Elgueta, Mario, Krolow, Tiago K. & Henriques, Augusto L., 2022, Catalog of the horse-flies (Diptera: Tabanidae) of Chile, pp. 201-257 in Zootaxa 5091 (2) on page 214, DOI: 10.11646/zootaxa.5091.2.1, http://zenodo.org/record/5843635
Model-based image segmentation in medical applications
Creators: name: Qian, Zhen
Publisher: name: No Publisher Supplied
Year: 2007

description: Image segmentation is an essential and indispensable step in medical image analysis. It partitions the image into meaningful anatomic or pathological structures. Because medical image segmentation needs high level medical and anatomic knowledge, model-based segmentation methods are highly desirable. In this thesis, we will first give a short survey of current approaches of medical image segmentation. Then we specifically develop appearance and shape models for different segmentation tasks. These models are either obtained from visual observation and prior human expertise, or from certain automaticmachine learning methods. In this thesis, two model-based image segmentation algorithms are developed for 3D MR colonography and 2D cardiac tagged MRI. For 3D MR colonography, we manually build the shape and intensity model. For 2D tagged MRI, we learn the shape and local appearance model from a training set. In each application, besides the models, we give complete details in solving the segmentation  problems, such as how we correct the MR image intensity inhomogeneity and how we automatically initialize the segmentation. Both model-based methods perform well on real medical image data.
Multiple Salivary Biomarkers for Lung Cancer Detection
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Lung cancer is the most common cause of cancer-related death in men and the second most common in women. In the U.S. it is estimated that there are 45 million current and 45 million former smokers at risk for developing lung cancer and this disease is estimated to remain a major health problem for at least the next 50 years. Over 75% of lung cancer patients are diagnosed in late stages because there remains no practical way to screen a large number of people at risk. Strategies to detect lung cancer at early stage and identify high-risk individuals are sorely needed. Lung cancer may be seen on chest x-ray and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. However, these procedures are either invasive, lack of specificity and sensitivity, or costly, which prevent them from large population screening. It is timely to develop a novel detection and screening tool for lung cancer. As a mirror of the body, saliva is readily accessible noninvasively. There are diverse contents in saliva, including DNA, RNA, protein and bacteria. It has been recognized that salivary contents are altered when the health status change. The altered telltale molecules, or biomarkers, could be used to monitor the health status, disease onset, treatment responsiveness and outcome. Informative biomarkers can serve as early sentinels for disease detection and screening. The goal of this TRDRP application is to develop a state-of-the-art method for early detection and screening of lung cancer, which is one of the TRDRP primary research areas. We hypothesize that clinically discriminatory biomarkers for lung cancer detection are present in saliva. Two high throughput technologies, specifically mRNA and bacterial approaches, will be applied to search for discriminatory biomarkers that could be used to screen large populations noninvasively and identify individuals with lung cancer at the early stage. The outcome of this study will provide multiple salivary biomarkers for screening and early detection of lung cancer. Our current data strongly support that the salivary mRNA and bacterial biomarkers will emerge as highly specific and sensitive tools for lung cancer detection in saliva, a non-invasive biofluid. We are optimistic that saliva-based early detection of lung cancer will offer the promise of improved cure rates of this high-impact cancer.
Pulmonary Rehabilitation in Sleep Disorders affecting COPD
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Sleep-related disorders have become an important public health concern. These are defined as any condition affecting the quality of sleep, including insomnia and all breathing-related sleep disorders such as the sleep apnea/hypopnea syndrome (SAHS). SAHS is a condition where there is little or no air flow going to the lungs because of an obstruction in the upper airway during sleep leading to decrease of blood oxygen levels and disturbed sleep. This condition can present at any age and affects up to 5% of the general population leading to serious health problems such as heart diseases, stroke, erectile dysfunction, diabetes, and depression. Sleep disorders are associated with impaired quality of life. Little is currently known about sleep disorders in patients with chronic obstructive pulmonary disease (COPD), the most common chronic lung disease and a major health problem directly related to cigarette smoking. Current treatment options for sleep-related disorders include continuous nasal pressure devices (CPAP), nocturnal oxygen therapy, oral medications such as non-benzodiazepines drugs and behavior therapy. Given the paucity of information about the impact of sleep disorders and treatments specific for patients with COPD further investigation of these two common conditions is warranted. In other populations, exercise has been shown to improve sleep health. In patients with COPD, pulmonary rehabilitation (PR), including exercise training, has been shown to produce important health benefits such as improvement in symptoms, exercise tolerance, and quality of life. However, the effect of PR on sleep-related disorders has not been previously studied in such patients. The purpose of this proposal, therefore, is to better characterize sleep-related disorders in patients with disabling, moderate to severe COPD and evaluate the potential benefits of PR as a possible treatment to improve sleep health in these patients. Our hypotheses are that in patients with COPD: 1) sleep health is poor; 2) sleep-related disorders are common; 3) poor sleep health is related to other measures of poor health outcomes; and 3) pulmonary rehabilitation may improve sleep health and reduce sleep-related disorders.
Coladenia indrani subsp. uposathra Fruhstorfer 1911
Creators: name: Bhowmik, Suman
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Hesperiidae
Coladenia
Coladenia indrani
Coladenia indrani uposathra fruhstorfer, [1911] (tricolour pied flat)

description: 15. Coladenia indrani uposathra Fruhstorfer, [1911] (Tricolour Pied Flat)
Remarks. A single individual was recorded in Jampui Hills (24°2’20” N & 92°16’19” E, ca. 329 m above msl.) till 04.vi.2016. Later three individuals were sighted in Ambassa, Dhalai District, on 15.iv.2017. Recently in October 2020 another individual was sighted at the same location in Jampui Hills. This species is rare throughout the state.
Current known distribution. Myanmar, India (Manipur) (Van Gasse 2013; Varshney & Smetacek 2015).
description: Published as part of Bhowmik, Suman, 2021, Fifty-one new additions to the butterfly (Lepidoptera: Rhopalocera) fauna of Tripura, North-east India, pp. 35-60 in Revista Chilena de Entomología (Rev. Chil. Entomol.) (Rev. Chil. Entomol.) 47 (1) on page 46, DOI: 10.35249/rche.47.1.21.04, http://zenodo.org/record/10950112
Gerosis bhagava subsp. bhagava
Creators: name: Bhowmik, Suman
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Hesperiidae
Gerosis
Gerosis bhagava
Gerosis bhagava bhagava (moore, [1866])

description: 16. Gerosis bhagava bhagava (Moore, [1866]) (Common Yellow-breast Flat)
Remarks. On 05.xii.2015, a single individual was recorded at Vanghmun (24°0’9” N & 92°16’44” E, ca. 571 m above msl.) in Jampui Hills, while resting on a Pteridophyte. This species is not common in Tripura.
Current known distribution. Nepal, Myanmar, India (Goa to Jharkhand and south to Kerala; Sikkim to Northeast India) (Van Gasse 2013; Varshney & Smetacek 2015).
description: Published as part of Bhowmik, Suman, 2021, Fifty-one new additions to the butterfly (Lepidoptera: Rhopalocera) fauna of Tripura, North-east India, pp. 35-60 in Revista Chilena de Entomología (Rev. Chil. Entomol.) (Rev. Chil. Entomol.) 47 (1) on page 46, DOI: 10.35249/rche.47.1.21.04, http://zenodo.org/record/10950112
Iridium catalyzed alkane dehydrogenation, olefin isomerization and related chemistry
Creators: name: Ray, Amlan
Publisher: name: No Publisher Supplied
Year: 2007

description: Excellent alkane dehydrogenation activity exhibited by the pincer-ligated iridium complexes of the type -- (X-RPCP)IrH2 (X-RPCP = 4-X-C6H2-2,6-(CH2PR2)2 with X = H, MeO; R = tBu, iPr) was exploited to functionalize a variety of aliphatic polyolefins via catalytic dehydrogenation. Of the two (MeO-RPCP)IrH2 complexes (2 : R = tBu and 3 : R = iPr) used for the study, 3 was found to be an extremely active system for dehydrogenation of poly(1-hexene), giving 100% conversion with respect to the initial concentration of norbornene (acceptor) used. The catalysts exhibited selectivity for dehydrogenation of polymer branches over the backbone, with a kinetic selectivity for terminal position of the branches. Isomerization of 1-octene conducted with iridium-pincer complexes 1 ((H-tBuPCP)IrH2) 2 and 3, having different steric and electronic tuning, suggested that a larger alkyl group (R) on the phosphines along with a stronger [pi sign]-donating group on the pincer aryl ring (X) resulted in lower rate and higher selectivity for isomerization. In a related study, insertion of an olefin into the Ir-H bonds of the complexes (H-tBuPCP)Ir(H)(Y) were investigated using cis-1,2-dideutero-1-octene as the substrate. In presence of the substrate octene, some (H-tBuPCP)Ir(H)(Y) complexes (Y = Ph, NHPh etc) showed labile behavior in solution, being present in equilibrium with a (H-tBuPCP)Ir(H)(1-octene) complex. Results of kinetic experiments suggested that [pi sign]-donating Y groups enhanced the rate of olefin insertion. DFT calculations carried out on the systems predicted a slight preference for a pathway in which olefin binds to the metal center in between H and Y with a trans arrangement to the PCP-aryl ring. The olefin bound 14-electron complex (PCP)Ir(1-octene) was characterized by low temperature 1H and 31P NMR.A new pincer complex (Me2N-tBuPCP)IrH2 (4d), having [pi sign]-electron rich iridium center, was synthesized and investigated for catalytic dehydrogenation. Complex 4d, was found to exhibit better selectivity and rate, as compared to the previously reported systems 1 and 2, for transfer dehydrogenation of branched and n-alkanes. It was also found to be a robust, slightly more stable and highly efficient catalyst for acceptorless dehydrogenation of cyclodecane.
NGAL-dependent Apoptosis Resistance in NSCLC
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Lung cancer is the leading cause of cancer-related death in the United States. The overall survival rate is only 15%. Most cases of lung cancer death, close to 90% in men and 80% in women, are caused by cigarette smoking, including second hand smoking. There is an urgent need to explore new treatment agents. Targeted cancer therapy is an emerging strategy because these agents specifically attack the molecular underpinnings of a tumor, promising remarkable efficacy with minimal toxicity. The Epithelial Growth Factor Receptor (EGFR) is an important target for lung cancer therapy, because lung cancer commonly has overexpressed EGFR or over-active EGFR. Treatment with EGFR targeted inhibitors such as gefitinib (Iressa) and erlotinib (Tarceva) has led to prolonged survival of some lung cancer patients. However, many lung cancer patients only partially respond to the drugs or relapse with drug resistance within months of beginning treatment. This has led to intensive efforts to define the mechanisms of such drug resistance.

 We generated a few erlotinib-resistant NSCLC cell lines as a model of erlotinib-resistant lung cancer. We found that a protein, neutrophil gelatinase associated lipocalin (NGAL, or lipocalin-2), was expressed at higher level in erlotinib resistant cells. Cells genetically manipulated to overexpress NGAL were more resistant to cell death induced by erlotinib treatment. Examination of proteins involved in cell death revealed that Bim, whose activity is prone to cell death, was decreased by NGAL. And the decreased Bim was responsible for NGAL-mediated erlotinib resistance. NGAL increased the phosphorylation of ERK1/2, which is commonly involved in enhancing cancer cell survival ability. Treating cells with erlotinib decreased ERK1/2 phosphorylation and induced Bim, however, this effect was alleviated by NGAL. Further studies showed that NGAL promoted Bim protein degradation, thus decreased Bim level. Mice inoculated with NGAL overexpressing cells were more resistance to growth inhibition induced by erlotinib treatment. Serum NGAL levels in patients who do not respond well to erlotinib treatment were higher compared to those who respond. Based on these data, we will investigate the mechanisms of NGAL-mediated cell death resistance in human lung cancer cells and delineate the NGAL signaling pathways. We will also determine whether serum or tumor NGAL levels predict response to erlotinib treatment. Our study will clarify the potentially important role of NGAL in erlotinib resistance of NSCLC and may identify NGAL as a possible biomarker of response to erlotinib in lung cancer patients.
Novel treatments for COPD with Statins
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Chronic Obstructive Pulmonary Disease is the fourth leading cause of death in the United States and currently there are no effective treatments. Approximately 80-90% of COPD cases can be attributed to smoking. COPD is an inflammatory pulmonary disease characterized by airflow limitation and presents as either chronic bronchitis, emphysema or both. The repeated exposure of the spontaneously hypertensive to tobacco smoke mimics the chronic lung inflammation representative of human COPD better than other rodent models. Specifically spontaneously hypertensive rats have a robust inflammatory response following tobacco smoke exposure, a sustained inflammatory response with continued exposure to tobacco smoke and progression in cellular changes symptomatic for COPD. The proposed work will use this SH rat model to better understand the progression of COPD, its correlation to anatomical changes in the lung and test Statins as a promising new treatment for COPD with the potential to prevent and reverse the smoke induced chronic inflammatory changes of the disease.
Mooreana trichoneura subsp. pralaya Yellow Flat
Creators: name: Bhowmik, Suman
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Hesperiidae
Mooreana
Mooreana trichoneura
Mooreana trichoneura pralaya (moore, [1866]) (yellow flat)

description: 17. Mooreana trichoneura pralaya (Moore, [1866]) (Yellow Flat)
Remarks. A single individual was recorded in Jampui Hills (24°2’20” N & 92°16’19” E, ca. 329 m above msl.), near to a waterfall on 03.vi.2018. In November 2019 two more individuals were sighted in the same area. This species is very rare in Tripura.
Current known distribution. Myanmar, India (Uttarakhand to Northeast India) (Van Gasse 2013; Varshney & Smetacek 2015).
description: Published as part of Bhowmik, Suman, 2021, Fifty-one new additions to the butterfly (Lepidoptera: Rhopalocera) fauna of Tripura, North-east India, pp. 35-60 in Revista Chilena de Entomología (Rev. Chil. Entomol.) (Rev. Chil. Entomol.) 47 (1) on page 46, DOI: 10.35249/rche.47.1.21.04, http://zenodo.org/record/10950112
How actors' reactions to deviance maintain racial stereotypes: the role of backlash and racial identity
Creators: name: Phelan, Julie E.
Publisher: name: No Publisher Supplied
Year: 2007

description: Previous research has demonstrated that reprisals for counterstereotypical behavior (i.e., backlash effects, Rudman, 1998) maintains cultural stereotypes by increasing the likelihood that deviant actors will hide their atypical behavior and decreasing their desire to identify with counterstereotypical domains (Rudman & Fairchild, 2004).  The present research examined how backlash impacts non-White male deviants (led to believe they succeeded in a White domain), tested social support as an intervention strategy, and examined the moderating role of racial identification.  Results revealed that high racial identification acted as a buffer against the negative effects of backlash.  In contrast, participants with low racial identification behaved defensively after backlash from a White confederate, but not a Black confederate.  Identification with the atypical domain was decreased after backlash, regardless of racial identification.  Implications of these findings for the role of backlash in cultural stereotype maintenance are discussed.
Drowsiness detection while driving using fractal analysis and wavelet transform
Creators: name: Parikh, Prachi
Publisher: name: No Publisher Supplied
Year: 2007

description: The EEG signal plays a key role as a nondestructive testing method in the diagnosis and functional determination of the brain. EEG recordings represent changes in alertness, arousal, sleep and cognition. Boredom, fatigue and monotony of a task may induce drowsiness that leads to a decrease in alertness. This can have serious consequences in tasks involving constant vigilance and control such as driving.  In the current study, EEG signals are recorded using a car simulator and analyzed using Fractal analysis and Wavelet Transform. It is observed that there is an increase in the alpha frequencies in the latter stages of driving indicating a state of drowsiness. The analysis techniques used provide results quickly, which is essential to provide instant feedback.
Quantum stochastic communication with photon-number squeezed light
Creators: name: Paramanandam, Joshua
Publisher: name: No Publisher Supplied
Year: 2007

description: Squeezed states of light have found importance in quantum cryptography due to the no-cloning theorem which prevents two states from being identical to each other. The quantum state with quadrature operators X1 and X2 can be visualized as a point in phase space with the center being l angle X1 r angle, l angle X2 r angle surrounded by an error region which satisfies the minimum uncertainty product  l angle Delta X [1 over 2] r angle l angle Delta X [2 over2] r angle=1/16. These states are intrinsically secure since one needs to know which quadrature the measurement is to be made and any attempt to measure the wrong quadratures with arbitrary accuracy would disturb the message. Of course, the eavesdropper cannot simultaneously measure both quadratures with infinite precision for each. This thesis describes a method that not only encodes information in the amplitudes of the quadratures alone but also in the uncertainty of those states. One example of  squeezed light is the number-phase squeezed state which satisfying the uncertainity relation l angle Delta n [superscript] 2 r angle l angle Delta phi [superscript] 2 r angle=1/4. An implementation is demonstrated where the information is encoded only in the photon number uncertainity and the phase variable is ignored.The barrier regulation mechanisms such as macroscopic coulomb blockade in semiconductor junction diodes are responsible for generating photon fluxes with penetration below the standard quantum limit(shot noise level). The thesis describes a comprehensive quantum mechanical Langevin model which details the various mechanisms responsible for producing photon number squeezing from the thermionic emission to the diffusion current limits. Quantities such as the pump fluctuations and cross correlation spectral densities are studied under constant current and constant voltage conditions. The research investigates the generation of photon number squeezed light from high efficiency light emitting diodes. A measurement setup for subshot noise is constructed and each stage is properly calibrated. Experiments were performed to determine the squeezing spectra and Fanofactors for the L2656 and the L9337 high efficiency LEDs. The L9337 produces a squeezing of 1.5dB below the shot noise level over a bandwidth of 25Mhz, the largest known penetration at room temperature. The quantum stochastic communicator is also demonstrated. The research shows that the switching elements used in the modulation of the electrical bias which in turn affect the regulation mechanisms do not affect the statistics of the emitted light under certain conditions. The decoding of the time varying variances is achieved by using time frequency analysis with the aid of the spectrum analyzer.
Demons, phantoms, monsters:law, bodies, and detention in the war on terror
Creators: name: Nisa, Richard
Publisher: name: No Publisher Supplied
Year: 2007

description: This thesis is a study of the political and legal geographies of detention and interrogation in the War on Terror.  First, as individual bodies are increasingly singled out for control based not on a breach of law, but on behavior that might reveal one's destructive intentions, how are various security techniques being absorbed into the legal frameworks of liberalism and mobilized spatially in international war prisons? Next, how does this focus on bodily contingencies and destructive potentiality modify the legal organization of violence in the landscape of international conflict?  Finally, how are new technologies of control and expertise being deployed to establish a fluid space for the exercise of State power, and what are the roles of agents of legal discourse--judges, lawyers, administrators--in securing this landscape? How do these spaces reflect a particularly neoliberal mode of detention?  In approaching these questions, I address relationships between state spatiality, law, and the detention of the human body in the ongoing War on Terror. I concentrate on the discursive and material thresholds that are often understood to organize the landscape of war: freedom and social control, legal and illegal violence, body and state, self and other. Through close analyses, I intend to show that legal discourse in the War on Terror occupies a rather tenuous position--being called upon to legitimize acts of war and violence while simultaneously revealing spaces that challenge the legitimacy of those very actions. Ultimately, this is a work interrogating the legal production of insides and outsides.
Protodasyapha (Protodasyapha) abaurea
Creators: name: González, Christian R.
name: Elgueta, Mario
name: Krolow, Tiago K.
name: Henriques, Augusto L.
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Tabanidae
Protodasyapha
Protodasyapha abaurea

description: Protodasyapha (Protodasyapha) abaurea (Philip, 1958)
Chaetopalpus abaureus Philip, 1958: 70.
Holotype. Male (CAS). Type locality: Chile, Coquimbo, 15 mi. s. Los Vilos.
Distribution. Chile: Región de Coquimbo (Choapa).
References. Fairchild, 1971: 4 (cat., Veprius); Coscarón, 1976: 90 (com., Veprius); Moucha, 1976: 17 (cat., Veprius); Arnaud, 1985: 92 (Philip’s species); Coscarón & González, 1991: 127 (Chile spp., Veprius); Fairchild & Burger, 1994: 30 (cat.); Coscarón, 1998: 349 (list, dist.); Coscarón & Papavero, 2009b: 31 (cat.).
description: Published as part of González, Christian R., Elgueta, Mario, Krolow, Tiago K. & Henriques, Augusto L., 2022, Catalog of the horse-flies (Diptera: Tabanidae) of Chile, pp. 201-257 in Zootaxa 5091 (2) on page 214, DOI: 10.11646/zootaxa.5091.2.1, http://zenodo.org/record/5843635
Roll-Call: an energy efficient radio frequency identification system.
Creators: name: Medhekar, Shweta
Publisher: name: No Publisher Supplied
Year: 2007

description: In this thesis, we investigate two of the major challenges in pervasive systems: energy efficiency and co-existence of uncoordinated wireless messages by exploring the design of a Radio Frequency Identification (RFID) system intended to support the simultaneous and real time monitoring of thousands of entities. These entities, which may be individuals or inventory items, each carry a low-power transmit-only tag and are monitored by a collection of networked base-stations reporting to a central database. We have built a customized transmit-only tag with a small form-factor, and have implemented a real-time monitoring application intended to verify the presence of each tag in order to detect potential disappearance of a tag (perhaps due to item theft). Throughout the construction of our system, we have carefully engineered it for extended tag lifetime and reliable monitoring capabilities in the presence of packet collisions, while keeping the tags small and inexpensive.The major challenge in this architecture (called Roll-Call) is to supply the energy needed for long range continuous tracking for a year or more of reporting once a second while keeping the tags (called PIPs) small and inexpensive. We have used this as a model problem for optimizing cost, size and lifetime across the entire pervasive, persistent system from firmware to protocol.