cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Surgical and oncological outcomes after preoperative FOLFIRINOX chemotherapy in resected pancreatic cancer : an international multicenter cohort study
Creators: name: Veldhuisen, Eran
name: Klompmaker, Sjors
name: Janssen, Quisette P.
name: Abu Hilal, Mohammed
name: Alseidi, Adnan
name: Balduzzi, Alberto
name: Balzano, Gianpaolo
name: Bassi, Claudio
name: Berrevoet, Frederik
name: Bond, Morgan
name: Busch, Olivier R.
name: Butturini, Giovanni
name: Conlon, Kevin C.
name: Frigerio, Isabella M.
name: Fusai, Giuseppe K.
name: Gagnière, Johan
name: Griffin, Oonagh
name: Hackert, Thilo
name: Halimi, Asif
name: Keck, Tobias
name: Kleeff, Jörg H.
name: Klaiber, Ulla
name: Labori, Knut J.
name: Lesurtel, Mickaël
name: Malleo, Giuseppe
name: Marino, Marco V.
name: Molenaar, I Quintus
name: Mortensen, Michael B.
name: Nikov, Andrej
name: Pagnanelli, Michele
name: Pandé, Rupaly
name: Pfeiffer, Per
name: Pietrasz, Daniel
name: Rangelova, Elena
name: Roberts, Keith J.
name: Sa Cunha, Antonio
name: Salvia, Roberto
name: Strobel, Oliver
name: Tarvainen, Timo
name: Wilmink, Johanna W.
name: Groot Koerkamp, Bas
name: Besselink, Marc G.
Publisher: name: Scientific Committee of the European-African Hepato-Pancreato-Biliary
Year: 2023
Subjects: subject: 610

description: Background. Preoperative FOLFIRINOX chemotherapy is increasingly administered to patients with borderline resectable (BRPC) and locally advanced pancreatic cancer (LAPC) to improve overall survival (OS). Multicenter studies reporting on the impact from the number of preoperative cycles and the use of adjuvant chemotherapy in relation to outcomes in this setting are lacking. This study aimed to assess the outcome of pancreatectomy after preoperative FOLFIRINOX, including predictors of OS. Methods. This international multicenter retrospective cohort study included patients from 31 centers in 19 European countries and the United States undergoing pancreatectomy after preoperative FOLFIRINOX chemotherapy (2012–2016). The primary end point was OS from diagnosis. Survival was assessed using Kaplan-Meier analysis and Cox regression. Results. The study included 423 patients who underwent pancreatectomy after a median of six (IQR 5–8) preoperative cycles of FOLFIRINOX. Postoperative major morbidity occurred for 88 (20.8%) patients and 90-day mortality for 12 (2.8%) patients. An R0 resection was achieved for 243 (57.4%) patients, and 259 (61.2%) patients received adjuvant chemotherapy. The median OS was 38 months (95% confidence interval [CI] 34–42 months) for BRPC and 33 months (95% CI 27–45 months) for LAPC. Overall survival was significantly associated with R0 resection (hazard ratio [HR] 1.63; 95% CI 1.20–2.20) and tumor differentiation (HR 1.43; 95% CI 1.08–1.91). Neither the number of preoperative chemotherapy cycles nor the use adjuvant chemotherapy was associated with OS. Conclusions. This international multicenter study found that pancreatectomy after FOLFIRINOX chemotherapy is associated with favorable outcomes for patients with BRPC and those with LAPC. Future studies should confirm that the number of neoadjuvant cycles and the use adjuvant chemotherapy have no relation to OS after resection.
Supplemental Material - Transitioning from paediatric to adult healthcare: Exploring the practices and experiences of care providers
Creators: name: Splane, Jennifer
name: Doucet, Shelley
name: Luke, Alison
Publisher: name: SAGE Journals
Year: 2023
Subjects: Health and Community Services
Nursing not elsewhere classified
Paediatrics

description: Supplemental Material for Transitioning from paediatric to adult healthcare: Exploring the practices and experiences of care providers by Jennifer Splane, Shelley Doucet, and Alison Luke in Journal of Child Health Care
IRAA : a statistical tool for investigating a protein-protein interaction interface from multiple structures
Creators: name: Belapure, Jaydeep
name: Sorokina, Marija
name: Kastritis, Panagiotis L.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 570

description: Understanding protein–protein interactions (PPIs) is fundamental to infer how different molecular systems work. A major component to model molecular recognition is the buried surface area (BSA), that is, the area that becomes inaccessible to solvent upon complex formation. To date, many attempts tried to connect BSA to molecular recognition principles, and in particular, to the underlying binding affinity. However, the most popular approach to calculate BSA is to use a single (or in some cases few) bound structures, consequently neglecting a wealth of structural information of the interacting proteins derived from ensembles corresponding to their unbound and bound states. Moreover, the most popular method inherently assumes the component proteins to bind as rigid entities. To address the above shortcomings, we developed a Monte Carlo method-based Interface Residue Assessment Algorithm (IRAA), to calculate a combined distribution of BSA for a given complex. Further, we apply our algorithm to human ACE2 and SARS-CoV-2 Spike protein complex, a system of prime importance. Results show a much broader distribution of BSA compared to that obtained from only the bound structure or structures and extended residue members of the interface with implications to the underlying biomolecular recognition. We derive that specific interface residues of ACE2 and of S-protein are consistently highly flexible, whereas other residues systematically show minor conformational variations. In effect, IRAA facilitates the use of all available structural data for any biomolecular complex of interest, extracting quantitative parameters with statistical significance, thereby providing a deeper biophysical understanding of the molecular system under investigation.
Additional file 8 of Net reclassification index in comparison of prognostic value of disseminated intravascular coagulation diagnostic criteria by Japanese Society on Thrombosis and Hemostasis and International Society on Thrombosis and Haemostasis: a multicenter prospective cohort study
Creators: name: Mori, Hirotaka
name: Harada-Shirado, Kayo
name: Kawano, Noriaki
name: Hayakawa, Mineji
name: Seki, Yoshinobu
name: Uchiyama, Toshimasa
name: Yamakawa, Kazuma
name: Ishikura, Hiroyasu
name: Irie, Yuhei
name: Nishio, Kenji
name: Yada, Noritaka
name: Okamoto, Kohji
name: Ikezoe, Takayuki
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Computational Biology

description: Supplementary Material 8
The Continuous Adjoint Method On Graphics Processing Units For Compressible Flows
Creators: name: Ghavami Nejad, M.,
name: Tsiakas, K.,
name: Asouti, V.,
name: Trompoulis, X.,
Publisher: name: Zenodo
Year: 2017
Subjects: Continuous Adjoint
Graphics Processing Units (GPUs)
Compressible Flows
optimization

description: Presentation illustrating the continuous adjoint method on graphics processing units for compressible flows
Peat and disinfectant powder used in swine husbandry systems : quantification of oral intake using toxic metals as potential markers
Creators: name: Koch, Felicitas
name: Schenkel, Hans
name: Bachmann, Martin
name: Zeyner, Annette
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 570

description: The use of enrichment and bedding materials in pig husbandry intends to comply with the animals’ behavioural needs to perform natural exploratory behaviour, which is strongly connected to foraging behaviour. It can thus be assumed that pigs will ingest a certain material quantity possibly posing a risk to animal health and food safety as previous studies identified contaminants in enrichment and bedding materials. However, risk assessment requires knowledge about the effective amount of ingested material. Voluntary material intake of pigs with free access to peat and disinfectant powder was estimated by measuring the tissue levels of toxic metals originating from the respective materials in 28 pigs (seven groups, n = 4) via inductively coupled plasma mass spectrometry and comparing the results to tissue levels of pigs fed with known amounts of metals. Additionally, as markers of consumption, n-alkanes and acid insoluble ash naturally occurring in the materials and titanium dioxide, added as an external marker to disinfectant powder, were analysed in pigs’ faeces. Tissue levels of toxic metals as well as marker analyses in pigs’ faeces could prove material consumption. Results revealed mean voluntary intake levels of peat and disinfectant powder by pigs up to 7% and 2% of the daily ration. Hence, a transfer of contained toxic metals into the food chain might occur. Although current maximum levels for toxic elements in animal tissues were not exceeded due to dietary inclusion of peat or disinfectant powder, dietary exposure through food of animal origin should be reduced to a possible minimum. This applies specifically for elements, where no health-based guidance values for humans could have been derived (e.g. arsenic). Thus, labelling guidelines for enrichment and bedding materials can be a perspective to limit the entry of toxic metals and trace elements into the environment.
Additional file 4 of Interactions between patterns of multimorbidity and functional status among hospitalized older patients: a novel approach using cluster analysis and association rule mining
Creators: name: Piacenza, Francesco
name: Di Rosa, Mirko
name: Soraci, Luca
name: Montesanto, Alberto
name: Corsonello, Andrea
name: Cherubini, Antonio
name: Fabbietti, Paolo
name: Provinciali, Mauro
name: Lisa, Rosamaria
name: Bonfigli, Anna Rita
name: Filicetti, Elvira
name: Greco, Giada Ida
name: Muglia, Lucia
name: Lattanzio, Fabrizia
name: Volpentesta, Mara
name: Biscetti, Leonardo
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 4: Table S4. List of the association rules showing disease relationships in cluster 1 and 2 of the moderately-severely dependent group. AF: atrial fibrillation; CAD: coronary artery disease/ischemic cardiomyopathy; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; CVD: cerebrovascular disease; HF: heart failure.
Solvent and catalyst free vitrimeric poly(ionic liquid) electrolytes
Creators: name: Katcharava, Zviadi
name: Zhou, Xiaozhuang
name: Bhandary, Rajesh
name: Sattler, Rene
name: Huth, Heiko
name: Beiner, Mario
name: Marinow, Anja
name: Binder, Wolfgang H.
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 540

description: Polymer electrolytes (PEs) are a promising alternative to overcome shortcomings of conventional lithium ion batteries (LiBs) and make them safer for users. Introduction of self-healing features in PEs additionally leads to prolonged life-time of LIBs, thus tackling cost and environmental issues. We here present solvent free, self-healable, reprocessable, thermally stable, conductive poly(ionic liquid) (PIL) consisting of pyrrolidinium-based repeating units. PEO-functionalized styrene was used as a co-monomer for improving mechanical properties and introducing pendant OH groups in the polymer backbone to act as a transient crosslinking site for boric acid, leading to the formation of dynamic boronic ester bonds, thus forming a vitrimeric material. Dynamic boronic ester linkages allow reprocessing (at 40 °C), reshaping and self-healing ability of PEs. A series of vitrimeric PILs by varying both monomers ratio and lithium salt (LiTFSI) content was synthesized and characterized. The conductivity reached 10−5 S cm−1 at 50 °C in the optimized composition. Moreover, the PILs rheological properties fit the required melt flow behavior (above 120 °C) for 3D printing via fused deposition modeling (FDM), offering the possibility to design batteries with more complex and diverse architectures.
Sistema per la manipolazione remota in vuoto dei bersagli per la camera di reazione di GALILEO installata presso i LNL
Creators: name: Simone, Coelli
name: Benzoni Giovanna
name: Capsoni Andrea
name: Gesmundo Carlo
name: Trotta Danilo
name: Boiano Ciro
name: Viscione Ennio
Publisher: name: INFN Open Access Repository
Year: 2018

description: The realisation of a remotely-controlled target-exchange system for the multi-detector

array GALILEO has been proposed to the Mechanical Design and Machine Workshop

Department of INFN Milano, with the following requirements: possibility of pre-loading

7-10 targets, including quartz and collimators for beam centering procedures; downstream

location in front of the beam-dump, almost 3 m away from the scattering chamber; minimum

material which can interact with the beam, and under vacuum working conditions,

with pressures around 10􀀀6 mbar. The system has been designed and built within the Mechanical

Design and Machine Workshop Department of INFN-Milano and installed onto

the GALILEO beam line at the LNL INFN laboratories in Legnaro.
Additional file 9 of Net reclassification index in comparison of prognostic value of disseminated intravascular coagulation diagnostic criteria by Japanese Society on Thrombosis and Hemostasis and International Society on Thrombosis and Haemostasis: a multicenter prospective cohort study
Creators: name: Mori, Hirotaka
name: Harada-Shirado, Kayo
name: Kawano, Noriaki
name: Hayakawa, Mineji
name: Seki, Yoshinobu
name: Uchiyama, Toshimasa
name: Yamakawa, Kazuma
name: Ishikura, Hiroyasu
name: Irie, Yuhei
name: Nishio, Kenji
name: Yada, Noritaka
name: Okamoto, Kohji
name: Ikezoe, Takayuki
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Computational Biology

description: Supplementary Material 9
An analysis of the spread of electric field within the cochlea for different devices including custom-made electrodes for subtotal cochleoectomy
Creators: name: Wagner, Luise
name: Plontke, Stefan K.-R.
name: Rahne, Torsten
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Objective: Cochlear implants (CIs) can restore hearing not only in patients with profound hearing loss and deafness, but also in patients following tumour removal of intra-cochlear schwannomas. In such cases, design and placement differ from conventional electrode insertion, in which the cochlea remains filled with fluid. Despite these technical and surgical differences, previous studies have tended to show positive results in speech perception in tumour patients. The purpose of this study is to retrospectively evaluate the ability to predict speech recognition outcomes using individual electric field spreads and to investigate worldwide unique tumour cases. Study design: In a retrospective analysis in a university tertiary center electric field spreads were compared between two groups of electrode designs implanted between 2009 and 2020 i.e., between lateral wall electrodes and custom-made perimodiolar electrode carriers from the same company. The voltage gradients were analysed and grouped with speech recognition results. Results: Differences in electrical field spreads were found between lateral wall electrodes and the custom-made perimodiolar electrodes, whereas a significant influence of electric fields on scores in speech recognition cannot be demonstrated. Conclusion: Prediction of speech recognition outcome based on electric field propagation results seems not feasible. Significant differences in field spread between electrode arrays can be clearly demonstrated. This observation and its relevance to hearing treatment and speech recognition should therefore be further investigated in upcoming studies.
Supplemental Material - Providing a Supportive Environment for Disclosure of Sexual Violence and Abuse in a Sexual and Reproductive Healthcare Setting: A Realist Review
Creators: name: Caswell, Rachel J.
name: Ross, Jonathan D. C.
name: Maidment, Ian
name: Bradbury-Jones, Caroline
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material for Providing a Supportive Environment for Disclosure of Sexual Violence and Abuse in a Sexual and Reproductive Healthcare Setting: A Realist Review by Rachel J. Caswell, Jonathan D. C. Ross, Ian Maidment, and Carrie Bradbury-Jones in Trauma, Violence, & Abuse
sj-docx-1-psx-10.1177_00323217221105170 – Supplemental material for Revisiting Elite Perceptions as Mediator of Elite Responsiveness to Public Opinion
Creators: name: Walgrave, Stefaan
name: Soroka, Stuart
name: Loewen, Peter
name: Sheafer, Tamir
name: Soontjens, Karolin
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-docx-1-psx-10.1177_00323217221105170 for Revisiting Elite Perceptions as Mediator of Elite Responsiveness to Public Opinion by Stefaan Walgrave, Stuart Soroka, Peter Loewen, Tamir Sheafer and Karolin Soontjens in Political Studies
Additional file 7 of Leveraging neighborhood representations of single-cell data to achieve sensitive DE testing with miloDE
Creators: name: Missarova, Alsu
name: Dann, Emma
name: Rosen, Leah
name: Satija, Rahul
name: Marioni, John
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Additional file 7: Peer review history
sj-pdf-1-ctj-10.1177_17407745221105106 – Supplemental material for Landscape of coronavirus disease 2019 clinical trials: New frontiers and challenges
Creators: name: Halabi, Susan
name: Zhou, Jinyi
name: He, Yijie
name: Bressler, Linda R
name: Hernandez, Adrian F
name: Turner, Nicholas A
name: Hong, Hwanhee
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: FOS: Clinical medicine
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-ctj-10.1177_17407745221105106 for Landscape of coronavirus disease 2019 clinical trials: New frontiers and challenges by Susan Halabi, Jinyi Zhou, Yijie He, Linda R Bressler, Adrian F Hernandez, Nicholas A Turner and Hwanhee Hong in Clinical Trials
Technology-based counselling for people with dementia and their informal carers : a systematic review and meta-analysis
Creators: name: Bauernschmidt, Dorothee Brigitte
name: Hirt, Julian
name: Langer, Gero
name: Meyer, Gabriele
name: Unverzagt, Susanne
name: Wilde, Fabian
name: Wittmann, Janina
name: Bieber, Anja Martha
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Background: Information technology can enhance timely and individual support for people with Alzheimer’s disease and other dementias and their informal carers. Objective: To review the effectiveness of technology-based counselling interventions for people with dementia and informal carers. Methods: Randomized controlled trials of remote dementia counselling interventions were included. We searched CINAHL, Cochrane Library, MEDLINE, PsycINFO, and the Web of Science Core Collection (April 2021) in combination with citation tracking and free web searching (October to November 2021). We provide meta-analyses for caregiver depression, burden, and self-efficacy/mastery and structured reporting for other outcomes. The Grading of Recommendations Assessment, Development and Evaluation approach and the Risk of Bias 2 tool were applied. Results: We included five randomized controlled trials involving 880 participants. Interventions were provided for carers (four studies) or dyads (one study). Carers were predominantly women and were the spouses or children of people with dementia. Counselling was delivered via telephone or videoconference with two to 23 sessions over 1 to 12 months. Control groups received educational and resource materials only, standard (helpline) services, non-directive support, or home visits. Meta-analysis for our primary outcome, depressive symptoms in carers, revealed no statistically significant effect (SMD –0.15; 95% CI –0.40 to 0.10). There were also no significant effects on burden and self-efficacy/mastery. We rated the certainty of evidence as low to very low and all outcomes at an overall high risk of bias. Conclusion: The effectiveness of technology-based counselling interventions for people with dementia and informal carers remains uncertain. Theory-based approaches are needed for the development and evaluation of these interventions.
Supersaturation as a galenic concept for improving the cutaneous bioavailability of drugs in topical therapy
Creators: name: Wohlrab, Johannes
name: Eichner, Adina
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: The essential force that allows an epicutaneously applied drug to penetrate the skin is mediated by diffusion. The physicochemical properties of the skin tissue at the site of application and the concentration gradient of the dissolved drug between the vehicle and the stratum corneum are decisive here. One way to specifically improve these diffusion conditions is to use supersaturation. This uses the physical principle of the difference between the solubility curve and precipitation curve (Ostwald-Miers range). During the conversion of the application vehicle into the segregation vehicle, supersaturation of the dissolved drug substance in a solvent is achieved by evaporation, e.g., of a solubilizer. In principle, the change in solubility can also be achieved by heating and then cooling a solution. This principle has already been realized in a formulation of a fixed combination of calcipotriol and betamethasone dipropionate, two lipophilic drugs susceptible to hydrolysis, and is available on the market as a spray foam.
sj-docx-2-rse-10.1177_07419325221102537 – Supplemental material for Improving Numeracy Skills in First Graders with low performance in early numeracy: A Randomized Controlled Trial
Creators: name: Lopez-Pedersen, Anita
name: Mononen, Riikka
name: Aunio, Pirjo
name: Scherer, Ronny
name: Melby-Lervåg, Monica
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Education
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-docx-2-rse-10.1177_07419325221102537 for Improving Numeracy Skills in First Graders with low performance in early numeracy: A Randomized Controlled Trial by Anita Lopez-Pedersen, Riikka Mononen, Pirjo Aunio, Ronny Scherer and Monica Melby-Lervåg in Remedial and Special Education
Cell type matters : competence for alkaloid metabolism differs in two seed-derived cell strains of Catharanthus roseus
Creators: name: L-Raorane, Manish
name: Manz, Christina
name: Hildebrandt, Sarah Lea
name: Mielke, Marion
name: Thieme, Marc
name: Keller, Judith
name: Bunzel, Mirko
name: Nick, Peter
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 615

description: Since the discovery of the anticancer drugs vinblastine and vincristine, Catharanthus roseus has been intensively studied for biosynthesis of several terpene indole alkaloids (TIAs). Due to their low abundance in plant tissues at a simultaneously high demand, modes of production alternative to conventional extraction are mandatory. Plant cell fermentation might become one of these alternatives, yet decades of research have shown limited success to certain product classes, leading to the question: how to preserve the intrinsic ability to produce TIAs (metabolic competence) in cell culture? We used the strategy to use the developmental potency of mature embryos to generate such strains. Two cell strains (C1and C4) from seed embryos of Catharanthus roseus were found to differ not only morphologically, but also in their metabolic competence. This differential competence became manifest not only under phytohormone elicitation, but also upon feeding with alkaloid pathway precursors. The more active strain C4 formed larger cell aggregates and was endowed with longer mitochondria. These cellular features were accompanied by higher alkaloid accumulation in response to methyl jasmonate (MeJA) elicitation. The levels of catharanthine could be increased significantly, while the concurrent vindoline branch of the pathway was blocked, such that no bisindole alkaloids were detectable. By feeding vindoline to MeJA-elicited C4 cells, vincristine became detectable; however, only to marginal amounts. In conclusion, these results show that cultured cells are not “de-differentiated”, but can differ in metabolic competence. In addition to elicitation and precursor feeding, the cellular properties of the “biomatter” are highly relevant for the success of plant cell fermentation.
Mapped Karst Groundwater Basins in the Harrodsburg 30 x 60 Minute Quadrangle
Creators: name: Currens, James C.
name: Paylor, Randall L.
name: Ray, Joseph A.
Publisher: name: Kentucky Geological Survey, University of Kentucky
Year: 2003

description: Abstract:
This map shows karst groundwater basins in the Harrodsburg quadrangle, determined primarily by groundwater tracer studies. It can be used to quickly identify the groundwater basins and springs to which a site may drain. Major springs and the relative size of their basin or catchment areas can be evaluated for potential as water supplies. The map also serves as a geographic index to literature on karst groundwater in the area.
Moraux, Paul, Der Aristotelismus bei den Griechen von Andronikos bis Alexander von Aphrodisias
Creators: name: Ricken, Friedo
Publisher: name: Theologie und Philosophie
Year: 1970

description: Theologie und Philosophie, Bd. 62 Nr. 1 (1987): Theologie und Philosophie, Band 62, Heft 1
sj-docx-1-aut-10.1177_13623613221112197 – Supplemental material for Psychiatry training in autism spectrum disorder and intellectual disability: Ongoing gaps and emerging opportunities
Creators: name: Marrus, Natasha
name: Koth, Kathleen A
name: Hellings, Jessica A
name: McDonald, Rachel
name: Gwynette, McLeod Frampton
name: Muhle, Rebecca
name: Lohr, William D
name: Vasa, RA
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences
subject: Education
subject: 130312 Special Education and Disability
subject: FOS: Educational sciences

description: Supplemental material, sj-docx-1-aut-10.1177_13623613221112197 for Psychiatry training in autism spectrum disorder and intellectual disability: Ongoing gaps and emerging opportunities by Natasha Marrus, Kathleen A Koth, Jessica A Hellings, Rachel McDonald, McLeod Frampton Gwynette, Rebecca Muhle, William D Lohr and RA Vasa in Autism
CD8+ and CD8- NKT cells exhibit phenotypic changes during pregnancy
Creators: name: Meggyes, Matyas
name: Nagy, David U.
name: Al Deen, Iyad Saad
name: Parkanyi, Borbala
name: Szereday, Laszlo
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Background: NKT cell population is a relatively well-characterized immune cell subset. Numerous publications have characterized the phenotypical features of its subpopulations even in human pregnancy. Nevertheless, there have not been studies investigating the distribution of the NKT cells based on the surface presence of the CD8 receptor. Methods: Thirty-four pregnant women from the first trimester, 30 from the second, and 36 from the third trimester of pregnancy in addition to 35 healthy non-pregnant women have been involved in the study. PBMCs were isolated from peripheral blood, CD8+ and CD8- NKT cells were then studied by flow cytometry using monoclonal antibodies. Immune checkpoint molecules and intracellular markers were also measured. Results: Substantial differences were revealed in the proportions of the NKT cell subpopulations in the healthy control cohort and the pregnant groups. By comparing the investigated groups, significant changes were detected in the expression levels of PD-L1, TIGIT, CD155, and NKG2D. Further associations were observed through examination of the relative expressions of TIGIT and CD226 in the CD8+ NKT subset. Conclusion: Data suggest that the CD8+ NKT cells are under fine regulation during healthy human pregnancy.
Supplemental Material - Why Australia should move towards nationally consistent mental health legislation?
Creators: name: Tosson, Daniel
name: Lam, Danny
name: Raeburn, Toby
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: Neuroscience

description: Supplemental Material for Why Australia should move towards nationally consistent mental health legislation? by Daniel Tosson, Danny Lam and Toby Raeburn in Australasian Psychiatry
A non-standard finite-difference-method for a non-autonomous epidemiological model: analysis, parameter identification and applications
Creators: name: Wacker, Benjamin
name: Schlüter, Christian Jan
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: In this work, we propose a new non-standard finite-difference-method for the numerical solution of the time-continuous non-autonomous susceptible-infected-recovered model. For our time-discrete numerical solution algorithm, we prove preservation of non-negativity and show that the unique time-discrete solution converges linearly towards the time-continuous unique solution. In addition to that, we introduce a parameter identification algorithm for the susceptible-infected-recovered model. Finally, we provide two numerical examples to stress our theoretical findings.
The Effects of Picture Activity Schedules on Transition Times in an Inclusive Preschool Classroom
Creators: name: Reis, Elizabeth A.
Publisher: name: University of Kentucky Libraries
Year: 2018

description: Abstract:
This study determined the effectiveness of using picture activity schedules with preschoolers who exhibited disruptive behaviors in an inclusive setting during transition times in a public preschool. The participants in this study were three male and one female student, ages 3 years to 5 years, who were enrolled in an inclusive public preschool. All children are Caucasian. Three of the children had an individualized education plan including goals for speech and social-emotional concerns. One child was typically developing and did not have an individualized education plan. The study method used a single-subject withdrawal design (ABAB). The results confirmed that the use of picture activity schedules decreased the mean duration of transitions and the duration returned to pre-intervention levels when picture activity schedules were removed for two of the four children.
Copyright: © Elizabeth A. Reis 2018
Generalized Geologic Map for Land-Use Planning: Edmonson County, Kentucky
Creators: name: Beck, E. Glynn
name: Williams, David A.
name: Carey, Daniel I.
Publisher: name: Kentucky Geological Survey, University of Kentucky
Year: 2003

description: Abstract:
This map is not intended to be used for selecting individual sites. Its purpose is to inform land-use planners, government officials, and the public in a general way about geologic bedrock conditions that affect the selection of sites for various purposes. The properties of thick soils may supercede those of the underlying bedrock and should be considered on a site to site basis. At any site, it is important to understand both the soils and the underlying rock.
sj-docx-2-aor-10.1177_00034894221115753 – Supplemental material for Thinking Beyond the Temporal Bone Lab: A Systematic Process for Expanding Surgical Simulation in Otolaryngology Training
Creators: name: James, Joel
name: Irace, Alexandria L.
name: A. Drusin, Madeleine
name: Kim, Ana H.
name: Gudis, David A.
name: Overdevest, Jonathan B.
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, sj-docx-2-aor-10.1177_00034894221115753 for Thinking Beyond the Temporal Bone Lab: A Systematic Process for Expanding Surgical Simulation in Otolaryngology Training by Joel James, Alexandria L. Irace, Madeleine A. Drusin, Ana H. Kim, David A. Gudis and Jonathan B. Overdevest in Annals of Otology, Rhinology & Laryngology
sj-pdf-4-mpp-10.1177_23814683221116304 – Supplemental material for Predictors of Decision Regret among Caregivers of Older Canadians Receiving Home Care: A Cross-Sectional Online Survey
Creators: name: Lognon, Tania
name: Gogovor, Amédé
name: Plourde, Karine V.
name: Holyoke, Paul
name: Lai, Claudia
name: Aubin, Emmanuelle
name: Kastner, Kathy
name: Canfield, Carolyn
name: Beleno, Ron
name: Stacey, Dawn
name: Rivest, Louis-Paul
name: Légaré, France
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-4-mpp-10.1177_23814683221116304 for Predictors of Decision Regret among Caregivers of Older Canadians Receiving Home Care: A Cross-Sectional Online Survey by Tania Lognon, Amédé Gogovor, Karine V. Plourde, Paul Holyoke, Claudia Lai, Emmanuelle Aubin, Kathy Kastner, Carolyn Canfield, Ron Beleno, Dawn Stacey, Louis-Paul Rivest and France Légaré in MDM Policy & Practice
Trends in the incidence of ovarian cancer in sub-Saharan Africa
Creators: name: Gizaw, Muluken
name: Parkin, Donald Maxwell
name: Stöter, Ole
name: Korir, Anne
name: Kamate, Bakarou
name: Liu, Biying
name: Bojang, Lamin
name: Kantelhardt, Eva Johanna
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2023
Subjects: subject: 610

description: Ovarian cancer (OC) is one of the commonest cancers of women in sub-Saharan Africa (SSA), although to date no data have been available on time trends in incidence to better understand the disease pattern in the region. We estimate time trends by histological subtype from 12 population-based cancer registries in 11 countries: Kenya (Nairobi), Mauritius, Seychelles, Uganda (Kampala), Congo (Brazzaville), Zimbabwe (Bulawayo and Harare), Cote d'Ivoire (Abidjan), The Gambia, Mali (Bamako), Nigeria (Ibadan) and South Africa (Eastern Cape). The selected registries were those that could provide consistent estimates of the incidence of ovarian cancer and with quality assessment for periods of 10 or more years. A total of 5423 cases of OC were included. Incidence rates have been increasing in all registries except Brazzaville, Congo, where a nonsignificant decline of 1% per year was seen. Statistically significant average annual increases were seen in Mauritius (2.5%), Bamako (5.3%), Ibadan (3.9%) and Eastern Cape (8%). Epithelial ovarian cancer was responsible for the increases observed in all registries. Statistically significant average annual percentage changes (AAPC) for epithelial OC were present in Bamako (AAPC = 5.9%), Ibadan (AAPC = 4.7%) and Eastern Cape (AAPC = 11.0%). Creating awareness among professionals of the growing importance of the disease is surely an important step to improving availability of, and access to, diagnosis and treatment of OC in SSA. Support must be given to the cancer registries to improve the availability of good-quality data on this important cancer.
Biological activity of prenylated pyranoflavanones from the stems of Derris reticulata
Creators: name: Khumsubdee, Sakunchai
name: Prawat, Hunsa
name: Kaweetripob, Wirongrong
name: Kheawchaum, Surasak
name: Boonsombat, Jutatip
name: Mahidol, Chulabhorn
name: Ruchirawat, Somsak
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The chemical investigation of the crude dichloromethane from the Derris reticulata stems led to the isolation of two new prenylated pyranoflavanones, dereticulatinal (1) and dereticulatinone (2). The structures were established by spectroscopic analysis and chemical transformation, and the absolute configurations of these isolates were deduced through CD comparison with that of lupinifolin. The cancer cytotoxicity study revealed that compound 1 showed cytotoxicity against MOLT-3 cell with an IC50 value of 40.17 ± 4.0 µM, while compound 2 showed cytotoxicity against MOLT-3 and HL-60 cells with IC50 values of 22.16 ± 2.3 and 38.99 ± 4.5 µM, respectively. In the chemopreventive assays, 1 and 2 exhibited strong anti-aromatase activity, with IC50 values of 1.27 ± 0.15 µM and 0.35 ± 0.04 µM, respectively. Compound 2 also showed inhibition activity in HL-60 assay with an IC50 value of 18.1 ± 0.3 µM. Two isolates showed no activities in DPPH and LOX assays.
Boonkumkhaoyai : The Thai-Isan Epitomic Model of Buddhist Economy and Dhammic Socialism
Creators: name: Dipti Mahanta
Publisher: name: Buddhist Research Institute
Year: 2015
Subjects: Boonkumkhaoyai,Thai,Isan Epitomic, Buddhist Economy,Dhammic Socialism

description: Journal of International Buddhist Studies, 6, 2
Supplemental Material - Early-Life Socioeconomic Disadvantage and Health in Late Middle-Age: Importance of Heterogeneous Income Trajectories
Creators: name: Kwon, Eunsun
name: Park, Sojung
name: Lee, Hyunjoo
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material for Early-Life Socioeconomic Disadvantage and Health in Late Middle-Age: Importance of Heterogeneous Income Trajectories by Eunsun Kwon, Sojung Park, and Hyunjoo Lee in Research on Aging
Supplemental Material – The Roles of Busyness and Daily Routine in Medication Management Behaviors Among Older Adults
Creators: name: Klinedinst, Tara C.
name: Opsasnick, Lauren
name: Benavente, Julia Yoshino
name: Wolf, Michael
name: O’Conor, Rachel
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material for The Roles of Busyness and Daily Routine in Medication Management Behaviors Among Older Adults by Tara C. Klinedinst, Lauren Opsasnick, Julia Yoshino Benavente, Michael Wolf, and Rachel O’Conor in Journal of Applied Gerontology
sj-docx-1-taj-10.1177_20406223231163115 – Supplemental material for Metformin adherence and the risk of cardiovascular disease: a population-based cohort study
Creators: name: Yu, Shun-Fan
name: Hong, Chien-Tai
name: Chen, Wan-Ting
name: Chan, Lung
name: Chien, Li-Nien
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Cardiology
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111702 Aged Health Care
subject: FOS: Health sciences
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 110203 Respiratory Diseases

description: Supplemental material, sj-docx-1-taj-10.1177_20406223231163115 for Metformin adherence and the risk of cardiovascular disease: a population-based cohort study by Shun-Fan Yu, Chien-Tai Hong, Wan-Ting Chen, Lung Chan and Li-Nien Chien in Therapeutic Advances in Chronic Disease
Supplemental Material - What if there were no personality factors? Comparing the predictability of behavioral act frequencies from a big-five and a maximal-dimensional item set
Creators: name: Altgassen, Elisa
name: Olaru, Gabriel
name: Wilhelm, Oliver
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental Material for What if there were no personality factors? Comparing the predictability of behavioral act frequencies from a big-five and a maximal-dimensional item set by Elisa Altgassen, Gabriel Olaru, and Oliver Wilhelm in European Journal of Personality
Additional file 4 of DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
Creators: name: Sabbatinelli, Jacopo
name: Giuliani, Angelica
name: Kwiatkowska, Katarzyna Malgorzata
name: Matacchione, Giulia
name: Belloni, Alessia
name: Ramini, Deborah
name: Prattichizzo, Francesco
name: Pellegrini, Valeria
name: Piacenza, Francesco
name: Tortato, Elena
name: Bonfigli, Anna Rita
name: Gentilini, Davide
name: Procopio, Antonio Domenico
name: Garagnani, Paolo
name: Olivieri, Fabiola
name: Bronte, Giuseppe
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary file 4.
title: Target dependent greedy sampling for Gaussian kernel PDE collocation
Creators: name: Vogel, Max-Paul
Publisher: name: Universität Stuttgart
Year: 2024
Subjects: subject: 510

description: This work develops a target-dependent greedy sampling strategy for solving PDEs using Gaussian kernel collocation within the reproducing kernel Hilbert space framework, achieving efficient and mesh-free approximation with exponential convergence rates.
Additional file 7 of DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
Creators: name: Sabbatinelli, Jacopo
name: Giuliani, Angelica
name: Kwiatkowska, Katarzyna Malgorzata
name: Matacchione, Giulia
name: Belloni, Alessia
name: Ramini, Deborah
name: Prattichizzo, Francesco
name: Pellegrini, Valeria
name: Piacenza, Francesco
name: Tortato, Elena
name: Bonfigli, Anna Rita
name: Gentilini, Davide
name: Procopio, Antonio Domenico
name: Garagnani, Paolo
name: Olivieri, Fabiola
name: Bronte, Giuseppe
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary file 7.
sj-pdf-1-mso-10.1177_20552173231198588 - Supplemental material for Treatment of older patients with multiple sclerosis: Results of an International Delphi Survey
Creators: name: Tumani, Hayrettin
name: Coyle, Patricia K
name: Cárcamo, Claudia
name: Cordioli, Cinzia
name: López, Pablo A
name: Peterka, Marek
name: Ramo-Tello, Cristina
name: Zuluaga, María I
name: Koster, Thijs
name: Vignos, Megan
Publisher: name: SAGE Journals
Year: 2023
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Neuroscience

description: Supplemental material, sj-pdf-1-mso-10.1177_20552173231198588 for Treatment of older patients with multiple sclerosis: Results of an International Delphi Survey by Hayrettin Tumani, Patricia K Coyle, Claudia Cárcamo, Cinzia Cordioli, Pablo A López, Marek Peterka, Cristina Ramo-Tello, María I Zuluaga, Thijs Koster and Megan Vignos in Multiple Sclerosis Journal – Experimental, Translational and Clinical
Additional file 7 of Mapping the influence of hydrocarbons mixture on molecular mechanisms, involved in breast and lung neoplasms: in silico toxicogenomic data-mining
Creators: name: Abu-Bakar, A’edah
name: Ismail, Maihani
name: Zulkifli, M. Zaqrul Ieman
name: Zaini, Nur Aini Sofiyya
name: Shukor, Nur Izzah Abd
name: Harun, Sarahani
name: Inayat-Hussain, Salmaan Hussain
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Supplementary Material 7
Deciphering the Bonding in Metavalent Materials for Next-Generation Memory
Creators: name: Jhaa, Dr. Gaurav
name: Kumari, Mithu
name: Chakkingal Parambil, Priyakumari
Publisher: name: Zenodo
Year: 2025
Subjects: metavalency
metavalent bonding
Born Effective Charge
half-bond order

description: The term metavalent bonding was introduced recently to describe bonds that are in between metallic and covalent. They are characterized by nearly half bond order, large Born Effective Charge (BEC), low band gap, moderate electrical conductivity, and large optical dielectric constant. While large BEC, half-bond order, and low band gap are often highlighted as their striking features, chemists are familiar with half-bond order systems. Hence, there is a reluctance to consider metavalency as a new bonding mechanism. Here, we use molecular orbital theory and DFT calculations to identify the uniqueness of the bonding in known metavalent materials and compare that with hypervalent half-bond order systems that are not classified as metavalent. We show that the metavalent materials are compounds with partial σ bonds formed mainly by p-p overlap and have low ionicity. If such systems have low band gaps due to low bonding-antibonding splitting or delocalization, that results in large BEC. This suggests that metavalency is not a new bonding mechanism.
Additional file 9 of DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
Creators: name: Sabbatinelli, Jacopo
name: Giuliani, Angelica
name: Kwiatkowska, Katarzyna Malgorzata
name: Matacchione, Giulia
name: Belloni, Alessia
name: Ramini, Deborah
name: Prattichizzo, Francesco
name: Pellegrini, Valeria
name: Piacenza, Francesco
name: Tortato, Elena
name: Bonfigli, Anna Rita
name: Gentilini, Davide
name: Procopio, Antonio Domenico
name: Garagnani, Paolo
name: Olivieri, Fabiola
name: Bronte, Giuseppe
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Supplementary file 9.