cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Hyboella guangxiensis Zheng & Jiang 1994
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hyboella
Hyboella guangxiensis

description: 39. Hyboella guangxiensis Zheng & Jiang, 1994
Specimens examined. 4 ♂ 3♀, Shangsi (Jiaoan), 21°59’N, 107°55’E, 400m alt, 16 Aug. 2012, collected by Li- Liang LIN.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 165, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Vergesellschaftung und Synökologie von Utricularia stygia im Fetzach-Taufach-Moor (Kreis Ravensburg) - ein neuer Fundort für Württemberg
Creators: name: Schmidt, Bertrand
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1995

description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
description: Bd. 151, 1995
Additional file 5: of An SNP-based saturated genetic map and QTL analysis of fruit-related traits in Zucchini using Genotyping-by-sequencing
Creators: name: Montero-Pau, Javier
name: Blanca, José
name: Esteras, Cristina
name: Martínez-Pérez, Eva
name: Gómez, Pedro
name: Monforte, Antonio
name: Cañizares, Joaquín
name: Picó, Belén
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology
subject: Computational Biology

description: Phenotypic values of RILs carrying Zucchini and Scallop alleles in the detected QTL regions. Means and standard errors of the phenotypic value of RILs belonging to the alternative allelic classes (Zuchini versus Scallop) for the markers in the LOD peak regions of each significant QTL are shown. Data of the three environments, combined and separate, are shown to validate the effects of the different QTLs (Paip2014, Paip2015, and UPV2015). (DOCX 39 kb)
Scambus goniozator Aubert 1982
Creators: name: Varga, Oleksandr
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Ichneumonidae
Scambus
Scambus goniozator

description: Scambus goniozator Aubert, 1982 (Fig. 9h)
Records. New record.
Material examined. Crimea: 1 ♀, Lavanda, SN, 1.v.2004, leg. M. Nesterov.
Distribution. Europe (only France); Ukraine: Crimea.
Biology. CSF. May.
description: Published as part of Varga, Oleksandr, 2019, Taxonomy and distribution of pimpline parasitoids (Hymenoptera, Ichneumonidae, Pimplinae) in Ukraine, pp. 1-65 in Zootaxa 4693 (1) on page 35, DOI: 10.11646/zootaxa.4693.1.1, http://zenodo.org/record/3529018
Steifgras (Catapodium rigidium (L.) C. E. HUBBARD) und Pariser Labkraut (Galium parisiense L.) auf den Fildern/Württemberg
Creators: name: Smettan, Hans
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1995

description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
description: Bd. 151, 1995
Quantum computing inspired paintings: reinterpreting classical masterpieces
Creators: name: Crippa, Arianna
name: Chai, Yahui
name: Hamido, Omar Costa
name: Itaborai, Paulo
name: Jansen, Karl
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2024

description: We aim to apply a quantum computing technique to compose artworks. The main idea is to revisit three paintings of different styles and historical periods: ''Narciso'', painted circa 1597-1599 by Michelangelo Merisi (Caravaggio), ''Les fils de l'homme'', painted in 1964 by Rene Magritte and ''192 Farben'', painted in 1966 by Gerard Richter. We utilize the output of a quantum computation to change the composition in the paintings, leading to a paintings series titled ''Quantum Transformation I, II, III''. In particular, the figures are discretized into square lattices and the order of the pieces is changed according to the result of the quantum simulation. We consider an Ising Hamiltonian as the observable in the quantum computation and its time evolution as the final outcome. From a classical subject to abstract forms, we seek to combine classical and quantum aesthetics through these three art pieces. Besides experimenting with hardware runs and circuit noise, our goal is to reproduce these works as physical oil paintings on wooden panels. With this process, we complete a full circle between classical and quantum techniques and contribute to rethinking Art practice in the era of quantum computing technologies.
Additional file 5: of An SNP-based saturated genetic map and QTL analysis of fruit-related traits in Zucchini using Genotyping-by-sequencing
Creators: name: Montero-Pau, Javier
name: Blanca, José
name: Esteras, Cristina
name: Martínez-Pérez, Eva
name: Gómez, Pedro
name: Monforte, Antonio
name: Cañizares, Joaquín
name: Picó, Belén
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology
subject: Computational Biology

description: Phenotypic values of RILs carrying Zucchini and Scallop alleles in the detected QTL regions. Means and standard errors of the phenotypic value of RILs belonging to the alternative allelic classes (Zuchini versus Scallop) for the markers in the LOD peak regions of each significant QTL are shown. Data of the three environments, combined and separate, are shown to validate the effects of the different QTLs (Paip2014, Paip2015, and UPV2015). (DOCX 39 kb)
Hyboella longinota Zheng & Jiang 2002
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Hyboella
Hyboella longinota

description: 40. Hyboella longinota Zheng & Jiang, 2002
Specimens examined. 2 ♂ 4♀, Shangsi (Jiaoan), 21°59’N, 107°55’E, 400m alt, 18 Aug. 2012, collected by Wei- An DENG.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 165, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 1: of Meeting report: the 5th International expert symposium in Fukushima on radiation and health
Creators: name: Saenko, Vladimir
name: Thomas, Geraldine
name: Yamashita, Shunichi
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology

description: Members of the Organizing Committee of the 5th International expert symposium in Fukushima on radiation and health (in alphabetical order). (DOC 30Â kb)
Über die Arten der Sektion Leptogalium LANGE sensu EHRENDORFER der Gattung Galium (Rubiaceae) auf der Schwäbischen Alb
Creators: name: Wörz, Arno
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1995

description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
description: Bd. 151, 1995
Detection of genomic alterations in liquid biopsies from patients with non-small cell lung cancer using FoundationOne Liquid CDx: a cost-effectiveness analysis
Creators: name: Isla, Dolores
name: Álvarez, Rosa
name: Arnal, María
name: Arriola, Edurne
name: Azkarate, Aitor
name: Azkona, Eider
name: García-Campelo, Rosario
name: Garrido, Pilar
name: Nadal, Ernest
name: Ortega, Ana L
name: Carcedo, David
name: Crespo, María
name: Lavara, Jesús
name: Córcoles, Fernando
name: Bernabé, Reyes
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Liquid biopsy (LB) is a non-invasive technique to detect genetic alterations by next-generation sequencing (NGS) when tissue biopsy is not available. This study aims to estimate in the Spanish setting, the cost-effectiveness of using FoundationOne Liquid CDx (F1L CDx), a novel blood-derived LB test based on NGS, versus non-molecular diagnosis (non-mDx) in patients with advanced non-small cell lung cancer (NSCLC) in whom tissue sampling is not feasible. A joint model was developed combining a decision-tree with partitioned survival models to calculate the costs and health outcomes over a lifetime horizon, comparing F1L CDx in LB versus non-mDx. Only direct costs (expressed in €of 2023) were included and a 3% discount rate for future costs and effects was considered. Health outcomes were expressed in Life Years (LYs) and Quality-Adjusted Life Years (QALYs). Utilities and treatment efficacy were obtained from the literature. An expert panel of 11 Spanish oncologists determined the treatment allocation and validated all model inputs and assumptions. Several sensitivity analyses were performed to assess the robustness of the results. In a hypothetical cohort of 1,000 patients, LB using F1L CDx would detect 386 alterations, so those patients could be treated with targeted therapies or enrolled in clinical trials. Cost-effectiveness results showed that F1L CDx provides greater effectiveness than non-mDx (+383.95 LYs and +305.94 QALYs), with an additional cost of €2,898,308. The incremental cost-utility ratio was €9,473/QALY gained. The probabilistic sensitivity analysis confirmed the robustness of the cost-effectiveness results. Various limitations inherent to cost-effectiveness analyses were described. LB with F1L CDx test is a cost-effective strategy in Spain for patients with advanced NSCLC without tissue sample available for molecular diagnosis, improving the personalized treatment of these patients.
Der Hammerschnegel, Deroceras sturanyi (SMIROTH 1894), Baden-Württember (Gastropoda: Agriolimacidae)
Creators: name: Adler, Martin
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1995

description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
description: Bd. 151, 1995
Zur Ökologie und Bestandsentwicklung des Sperlingskauzes (Glaucidium passerinum) im Schwarzwald
Creators: name: König, Claus
name: Kaiser, Helmut
name: Mörike, Doris
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1995

description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
description: Bd. 151, 1995
title: Regional Energy Transition Accelerator - Bay of Plenty - Geothermal Energy Assessment
Creators: name: Carey, Brian S.
name: Alcaraz, Samantha A.
name: Wells, C.
name: Carden, Y
name: Moore, G.
Publisher: name: GNS Science
publisherIdentifier: https://ror.org/03vaqfv64
publisherIdentifierScheme: ROR
Year: 2024

description: The Regional Energy Transition Accelerator (RETA) project driven by the Energy Efficiency and Conservation Authority (EECA) aims to develop an understanding of what is needed to decarbonise each region in New Zealand. The objective is to develop a well-informed and coordinated approach for regional decarbonisation by understanding unique region-specific opportunities and barriers when developing regional energy transition roadmaps. It is EECA’s intention to make available the information required to optimise the choice of sustainable energy options in the transition away from fossil fuels. The scope of this work is a geothermal assessment specific to the broader Bay of Plenty (BOP) region. The region is known for its natural geothermal phenomena like hot springs, geysers and boiling mud in Rotorua, and for different uses of this resource, such as therapeutic hot bathing pools in Tauranga and Rotorua, and industrial applications in Kawerau. The region encompasses high temperature systems at Rotorua and Kawerau (>150C), and low temperature systems (<150C) at Tauranga and Awakeri, and near ambient temperature groundwater resources across the region. This is the first RETA that includes geothermal energy. As requested by EECA, the Reporoa Geothermal Field, located in the Waikato region, is also included in this assessment. The report introduces the reader to the key concepts of geothermal energy use for heat supply and various applicable regulatory regimes, including relating to geothermal greenhouse gas emissions and the Climate Change Response Act 2002 and regulations. Analysis of data from these identifies that significant operational greenhouse gas emission reductions (compared with natural gas providing heat for the same duty) can be achieved using geothermal and ground source heat pump (GSHP) technologies.
Macromotettixoides jiuwanshanensus Zheng, Wei & Jiang 2005
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Macromotettixoides
Macromotettixoides jiuwanshanensus

description: 41. Macromotettixoides jiuwanshanensus Zheng, Wei & Jiang, 2005
Specimens examined. 12 ♂ 14♀, Shangsi (Nanping), 21°52’N, 107°49’E, 400m alt, 19 Aug. 2012, collected by Wei-An DENG.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 165, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Biologie und Bestimmungsschlüssel der Larven der Gattung Chaoborus (Diptera: Chaoboridae)
Creators: name: Müller, Thomas Volker
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1995

description: Jahreshefte der Gesellschaft für Naturkunde in Württemberg
description: Bd. 151, 1995
Clinical and economic outcomes of assigning percutaneous coronary intervention patients to contrast-sparing strategies based on the predicted risk of contrast-induced acute kidney injury
Creators: name: Griffiths, Robert I.
name: Bhave, Aparna
name: McGovern, Alysha M.
name: Hargens, Liesl M.
name: Solid, Craig A.
name: Amin, Amit P.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Marine Biology
Science Policy
Computational Biology

description: Contrast-sparing strategies have been developed for percutaneous coronary intervention (PCI) patients at increased risk of contrast-induced acute kidney injury (CI-AKI), and numerous CI-AKI risk prediction models have been created. However, the potential clinical and economic consequences of using predicted CI-AKI risk thresholds for assigning patients to contrast-sparing regimens have not been evaluated. We estimated the clinical and economic consequences of alternative CI-AKI risk thresholds for assigning Medicare PCI patients to contrast-sparing strategies. Medicare data were used to identify inpatient PCI from January 2017 to June 2021. A prediction model was developed to assign each patient a predicted probability of CI-AKI. Multivariable modeling was used to assign each patient two marginal predicted values for each of several clinical and economic outcomes based on (1) their underlying clinical and procedural characteristics plus their true CI-AKI status in the data and (2) their characteristics plus their counterfactual CI-AKI status. Specifically, CI-AKI patients above the predicted risk threshold for contrast-sparing were reassigned their no CI-AKI (counterfactual) outcomes. Expected event rates, resource use, and costs were estimated before and after those CI-AKI patients were reassigned their counterfactual outcomes. This entailed bootstrapped sampling of the full cohort. Of the 542,813 patients in the study cohort, 5,802 (1.1%) had CI-AKI. The area under the receiver operating characteristic curve for the prediction model was 0.81. At a predicted risk threshold for CI-AKI of >2%, approximately 18.0% of PCI patients were assigned to contrast-sparing strategies, resulting in (/100,000 PCI patients) 121 fewer deaths, 58 fewer myocardial infarction readmissions, 4,303 fewer PCI hospital days, $11.3 million PCI cost savings, and $25.8 million total one-year cost savings, versus no contrast-sparing strategies. Claims data may not fully capture disease burden and are subject to inherent limitations such as coding inaccuracies. Further, the dataset used reflects only individuals with fee-for-service Medicare, and the results may not be generalizable to Medicare Advantage or other patient populations. Assignment to contrast-sparing regimens at a predicted risk threshold close to the underlying incidence of CI-AKI is projected to result in significant clinical and economic benefits.
Additional file 1: Figure S1. of Parasite infection of public databases: a data mining approach to identify apicomplexan contaminations in animal genome and transcriptome assemblies
Creators: name: Borner, Janus
name: Burmester, Thorsten
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Majority-rule consensus tree based on a PhyloBayes analysis of complete mitochondrial genomes from ape-infecting Plasmodium parasites. The alignment is based on the mitochondrial dataset from Liu et al. (2010) and only contains sequences from Clades C1 (from Chimpanzees) and G1 (from Gorillas; also contains human P. falciparum). Two contigs from the Gorilla genome assembly, which contain parasite-derived mitochondrial fragments, were added to the alignment. Bayesian posterior probabilities are given at the nodes. The tree was rooted with the C1 clade of Chimpanzee-infecting Plasmodium parasites. All EMBL/Genbank acc. nos. are given in parentheses. (PDF 236 kb)
Costs of breast cancer recurrence after initial treatment for HR+, HER2−, high-risk early breast cancer: estimates from SEER-Medicare linked data
Creators: name: Vitko, Alexandra S.
name: Martin, Pam
name: Zhang, Sheng
name: Johnston, Adam
name: Ohsfeldt, Robert
name: Zheng, Shen
name: Liepa, Astra M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: To assess the costs of treated recurrence and survival in elderly patients with early breast cancer (EBC) at high risk of recurrence using Surveillance Epidemiology and End Results (SEER) registry-Medicare linked claims data. This retrospective study included patients aged ≥65 years with hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2−), node-positive EBC at high risk of recurrence. Treated recurrences were defined based on treatment events/procedure codes from claims. Primary outcomes were monthly total extra costs and cumulative extra costs of treated recurrence relative to patients with non/untreated recurrence. Costs were calculated using a Kaplan-Meier sampling average estimator method and inflated to 2021 US$. Secondary outcomes included analysis by recurrence type and overall survival (OS) after recurrence. Subgroup analysis evaluated costs in patients with Medicare Part D coverage. Among 3,081 eligible patients [mean (SD) age at diagnosis was 74.5 (7.1) years], the majority were females (97.4%) and white (87.8%). Treated recurrence was observed in 964 patients (31.3%). The monthly extra cost of treated recurrence was highest at the beginning of the first treated recurrence episode, with 6-year cumulative cost of $117,926. Six-year cumulative extra costs were higher for patients with distant recurrences ($168,656) than for patients with locoregional recurrences ($96,465). Median OS was 4.34 years for all treated recurrences, 1.92 years for distant recurrence, and 6.78 years for locoregional recurrence. Similar cumulative extra cost trends were observed in the subgroup with Part D coverage as in the overall population. This study utilizes claims data to identify treated recurrence. Due to age constraints of the dataset, results may not extrapolate to a younger population where EBC is commonly diagnosed. EBC recurrence in this elderly population has substantial costs, particularly in patients with distant recurrences. Therapies that delay or prevent recurrence may reduce long-term costs significantly.
Cost-effectiveness of add-on empagliflozin versus standard of care in management of CKD in Malaysia, Thailand and Vietnam – findings from a modelling study assessing an EMPA-KIDNEY eligible population, using CKD progression model
Creators: name: Varghese, Lijoy
name: Chang, Poh Wan
name: Juntarasiripas, Sorrakorn
name: Pham, Hien
name: Uster, Anastasia
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: Nearly one in ten individuals in South-East Asia are estimated to be affected by chronic kidney disease (CKD). The burden of end-stage kidney disease is significant and can be heavy on the healthcare system. The recent EMPA-KIDNEY trial demonstrated a significant reduction in the risk of kidney disease progression or cardiovascular death in patients with CKD with a broad range of kidney function using add-on empagliflozin versus standard of care (SoC) alone. The objective of this study was to estimate the economic benefit of empagliflozin for patients with CKD in Malaysia, Thailand and Vietnam. An individual patient level simulation model with an annual cycle that estimates the progression of kidney function and associated risk-factors was employed. Local costs and mortality rates were estimated from a wide range of published literature. A healthcare perspective was used over a 50-year time horizon. The use of add-on empagliflozin versus SoC alone was found to be cost-saving in Malaysia and Thailand and cost-effective (ICER: 77,838,407 Vietnam Dong/QALY vs. a willingness to pay threshold of 96,890,026/QALY) in Vietnam. The bulk of the costs avoided over a lifetime is derived from the prevention or delay of dialysis initiation or kidney transplant – the cost offsets were nearly twice the additional treatment cost. The results were similar in patients with and without diabetes and across broad range of albuminuria. The use of add-on empagliflozin in a broad population of patients with CKD is expected to be cost-saving in Malaysia and Thailand and cost-effective in Vietnam and will help alleviate the increasing burden of CKD in the region.
Exploiting network structure in NEST: Efficient communication in brain-scale simulations
Creators: name: Lober, Melissa
name: Diesmann, Markus
name: Kunkel, Susanne
Publisher: name: Forschungzentrum Jülich
Year: 2024

description: NEST Conference 2024, virtual, RWTH Aachen, virtual, 17 Jun 2024 - 18 Jun 2024
description: The communication of spike events constitutes a major bottleneck in simulations of brain-scale networks with realistic connectivity. Models such as the multi-area model1 not only have a dense connectivity within areas but also between areas. Synaptic transmission delays within an area can be as short as 0.1 ms and therefore simulations require frequent spike communication between compute nodes to maintain causality in the network dynamics2. This poses a challenge to the conventional round-robin scheme used to distribute neurons uniformly across compute nodes disregarding the network’s specific topology.We target this challenge and propose a structure-aware neuron distribution scheme along with a novel spike-communication framework that exploits this approach in order to make communication in large-scale distributed simulations more efficient. In the structure-aware neuron distribution scheme, neurons are placed on the hardware in a way that mimics the network’s topology. Paired with a communication framework that distinguishes local short delay intra-area communication and global long delay inter-area communication, the structure-aware approach minimizes the costly global communication and thereby reduces simulation time. Our prototype implementation is fully tested and was developed within the neuronal simulator tool NEST3.For the benchmarking of our approach, we developed a multi-area model that resembles the macaque multi-area model in terms of connectivity and work load, while being more easily scalable as it retains constant activity levels. We show that the new strategy significantly reduces communication time in weak-scaling experiments and the effect increases with an increasing number of compute nodes.[1] Schmidt et al., PLoS Comput Biol, 14(10), 1-38, 2018[2] Morrison & Diesmann, Springer Berlin Heidelberg, pp 267-278, 2008[3] Gewaltig & Diesmann, Scholarpedia 2(4):1430 , 2007
Bolivaritettix Gunther 1939
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Bolivaritettix

description: Genus Bolivaritettix Günther, 1939
Description. Head not exserted above pronotum, vertex generally wider than one eye (horizontal diameter of eyes). Antennae filiform, inserted between lower margins of eyes. Eyes not exserted above pronotal surface. Pronotum truncate anteriorly, subulate posteriorly and extends beyond apex of hind femora. Posterior margins of lateral lobes of pronotum with two concavities, posterior angles of lateral lobes of pronotum produced outwards, obliquely truncate behind. Tegmina long and oval, apex round. Wings generally present. Margins of fore and middle femora entire. Margins of hind femora finely serrulate. First and third hind tarsal segments equal in length. Bolivaritettix Günther is similar to Lamellitettix Hancock from which it differs in surface of pronotum with only short obsolescent longitudinal wrinkles, lacking protubrances on the margins and carinae; vertex seen from in front not sunken between the eyes. (median carinae between the shoulders and the foreshortened oblique intermediate carinae between the shoulders usually with smaller distinct protuberances; vertex seen from in front clearly sunken between the eyes, usually with small vertex protuberances in Lamellitettix.)
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 165, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 1: of Developing a framework to guide the de-adoption of low-value clinical practices in acute care medicine: a study protocol
Creators: name: Leigh, Jeanna Parsons
name: Niven, Daniel
name: Boyd, Jamie
name: Stelfox, Henry
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Developmental Biology
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: PROSPERO Registration. (PDF 52 kb)
Cost-effectiveness analysis of a lung cancer screening program in the Netherlands: a simulation based on NELSON and NLST study outcomes
Creators: name: Berge, Hilde ten
name: Willems, Bo
name: Pan, Xuanqi
name: Dvortsin, Evgeni
name: Aerts, Joachim
name: Postma, Maarten J.
name: Prokop, Mathias
name: van den Heuvel, Michel M.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: In the Netherlands, lung cancer is the leading cause of cancer-related death, accounting for more than 10,000 annual deaths. Lung cancer screening (LCS) studies using low-dose computed tomography (LDCT) have demonstrated that early detection reduces lung cancer mortality. However, no LCS program has been implemented yet in the Netherlands. A national LCS program has the potential to enhance the health outcomes for lung cancer patients in the Netherlands. This study evaluates the cost-effectiveness of LCS compared to no-screening in the Netherlands, by simulating the screening outcomes based on data from NEderlands–Leuvens Longkanker Screenings ONderzoek (NELSON) and National Lung Screening Trial (NLST). We simulated annual screening up to 74 years of age, using inclusion criteria from the respective studies. A decision tree and Markov model was used to predict the incremental costs, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratio (ICERs) for the screening population. The analysis used a lifetime horizon and a societal perspective. Compared to no-screening, LCS resulted in an ICER of €5,169 per QALY for the NELSON simulation, and an ICER of €17,119 per QALY for the NLST simulation. The screening costs were highly impactful for the cost-effectiveness. The most influential parameter was the CT scan cost. Cost reduction for CT from €201 to €101 per scan would reduce the ICER to €2,335 using NELSON criteria. Additionally, LCS could prevent 15,115 and 12,611 premature lung cancer deaths, accompanied by 1.66 and 1.31 QALYs gained per lung cancer case for the NELSON and NLST simulations, respectively. LCS was estimated to be cost-effective in the Netherlands for both simulations at a willingness-to-pay threshold of €20,000 per QALY. Using the NELSON criteria, less than €5,500 per QALY had to be spent. Lowering the cost per CT exam would lead to a further reduction of this amount.
Additional file 1: of The effects of ventilation tubes versus no ventilation tubes for recurrent acute otitis media or chronic otitis media with effusion in 9 to 36Â month old Greenlandic children, the SIUTIT trial: study protocol for a randomized controlled trial
Creators: name: Demant, Malene
name: Jensen, Ramon
name: Jakobsen, Janus
name: Gluud, Christian
name: HomĂ¸E, Preben
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: SPIRIT 2013 Checklist. (DOCX 61 kb)
Additional file 1: Figure S1. of Parasite infection of public databases: a data mining approach to identify apicomplexan contaminations in animal genome and transcriptome assemblies
Creators: name: Borner, Janus
name: Burmester, Thorsten
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Majority-rule consensus tree based on a PhyloBayes analysis of complete mitochondrial genomes from ape-infecting Plasmodium parasites. The alignment is based on the mitochondrial dataset from Liu et al. (2010) and only contains sequences from Clades C1 (from Chimpanzees) and G1 (from Gorillas; also contains human P. falciparum). Two contigs from the Gorilla genome assembly, which contain parasite-derived mitochondrial fragments, were added to the alignment. Bayesian posterior probabilities are given at the nodes. The tree was rooted with the C1 clade of Chimpanzee-infecting Plasmodium parasites. All EMBL/Genbank acc. nos. are given in parentheses. (PDF 236 kb)
Costs of breast cancer recurrence after initial treatment for HR+, HER2-, high-risk early breast cancer: estimates from SEER-Medicare linked data
Creators: name: Vitko, Alexandra S.
name: Martin, Pam
name: Zhang, Sheng
name: Johnston, Adam
name: Ohsfeldt, Robert
name: Zheng, Shen
name: Liepa, Astra M.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: To assess the costs of treated recurrence and survival in elderly patients with early breast cancer (EBC) at high risk of recurrence using Surveillance Epidemiology and End Results (SEER) registry-Medicare linked claims data. This retrospective study included patients aged ≥65 years with hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2-), node-positive EBC at high risk of recurrence. Treated recurrences were defined based on treatment events/procedure codes from claims. Primary outcomes were monthly total extra costs and cumulative extra costs of treated recurrence relative to patients with non/untreated recurrence. Costs were calculated using Kaplan-Meier sampling average estimator method and inflated to 2021 US$. Secondary outcomes included analysis by recurrence type and overall survival (OS) after recurrence. Subgroup analysis evaluated costs in patients with Medicare Part D coverage. Among 3081 eligible patients [mean (SD) age at diagnosis was 74.5 (7.1) years], the majority were females (97.4%) and white (87.8%). Treated recurrence was observed in 964 patients (31.3%). The monthly extra cost of treated recurrence was highest at the beginning of the first treated recurrence episode with 6-year cumulative cost of $117,926. Six-year cumulative extra costs were higher for patients with distant recurrences ($168,656) than for patients with locoregional recurrences ($96,465). Median OS was 4.34 years for all treated recurrences, 1.92 years for distant recurrence, and 6.78 years for locoregional recurrence. Similar cumulative extra cost trends were observed in the subgroup with Part D coverage as in the overall population. This study utilizes claims data to identify treated recurrence. Due to age constraints of the dataset, results may not extrapolate to a younger population where EBC is commonly diagnosed. EBC recurrence in this elderly population has substantial costs, particularly in patients with distant recurrences. Therapies that delay or prevent recurrence may reduce long-term costs significantly.
Bolivaritettix laticeps Bolivar 1909
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Bolivaritettix
Bolivaritettix laticeps

description: 42. Bolivaritettix laticeps (Bolívar, 1909)
Specimens examined. 3 ♂ 2♀, Dazhi, Qinzhou, 22°05’N, 108°14’E, 300m alt, 16 Aug. 2012, collected by Guang- Hai ZHANG.
Distribution. China (Guangxi, Yunnan); Nepal; India.
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 166, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Additional file 3: of Effects of community health volunteers on infectious diseases of children under five in Volta Region, Ghana: study protocol for a cluster randomized controlled trial
Creators: name: Yeonji Ma
name: Heunghee Kim
name: Yinseo Cho
name: Jaeeun Lee
name: Degley, Joseph
name: Abdul-Ghaffa Adam
name: Gyuhong Lee
name: Hoonsang Lee
name: Seungman Cha
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Booklet for CHVs. (DOCX 8322 kb)
Additional file 3: Table S3. of Maternal intake of seafood and supplementary long chain n-3 poly-unsaturated fatty acids and preterm delivery
Creators: name: Brantsæter, Anne
name: Englund-Ögge, Linda
name: Haugen, Margareta
name: Bryndis Birgisdottir
name: Knutsen, Helle
name: Sengpiel, Verena
name: Myhre, Ronny
name: Alexander, Jan
name: Nilsen, Roy
name: Jacobsson, Bo
name: Meltzer, Helle
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Associations between total seafood intake and marine long chain polyunsaturated fatty acids (LCn-3PUFA) from supplements and preterm delivery in women stratified according to nulliparous (n = 34,731) and parous women (n = 32,276) in the Norwegian Mother and Child Cohort Study (MoBa) 2002–2008. (DOC 43 kb)
Additional file 3: of Effects of community health volunteers on infectious diseases of children under five in Volta Region, Ghana: study protocol for a cluster randomized controlled trial
Creators: name: Yeonji Ma
name: Heunghee Kim
name: Yinseo Cho
name: Jaeeun Lee
name: Degley, Joseph
name: Abdul-Ghaffa Adam
name: Gyuhong Lee
name: Hoonsang Lee
name: Seungman Cha
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Booklet for CHVs. (DOCX 8322 kb)
Vaccine preparation time, errors, satisfaction, and preference of prefilled syringes versus RSV vaccines requiring reconstitution: randomized, time and motion study
Creators: name: Mehta, Darshan
name: Kimball-Carroll, Samantha
name: Clark, Dayna R.
name: Fossati, Serena
name: Hunger, Matthias
name: Pahwa, Ankit
name: Malmenäs, Mia
name: Hille, Brian
name: Van de Velde, Nicolas
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: The current study compared preparation time, errors, satisfaction, and preference for a prefilled syringe (PFS) versus two RSV vaccines requiring reconstitution (VRR1 and VRR2) in a randomized, single-blinded time and motion study. Pharmacists, nurses, and pharmacy technicians were randomized to a preparation sequence of the three vaccines. Participants read instructions, then consecutively prepared the three vaccines with a 3–5-min washout period in between. Preparations were video recorded and reviewed by a trained pharmacist for preparation time and errors using predefined, vaccine-specific checklists. Participant demographics, satisfaction with vaccine preparation, and vaccine preference were recorded. Within-subjects analysis of variance was used to compare preparation time. Mixed-effects Poisson and ordered logistic regression models were used to compare the number of preparation errors and satisfaction scores, respectively. Sixty-three pharmacists (60%), nurses (35%), and pharmacy technicians (5%) participated at four sites in the United States. The least squares mean preparation time per dose for PFS was 141.8 s (95% CI = 156.8–126.7; p <.0001) faster than for VRR1, 103.6 s (95% CI = 118.7–88.5; p <.0001) faster than for VRR2, and 122.7 s (95% CI = 134.2–111.2; p <.0001) faster than the pooled VRRs. Overall satisfaction (combined “Very” and “Extremely”) was 87.3% for PFS, 28.6% for VRR1, and 47.6% for VRR2. Most participants (81.0%) preferred the PFS vaccine. The study is limited by the inability to completely blind observers. To minimize the effects of order, we utilized a 3-sequence block design; however, the order in which the vaccines were prepared may have affected outcomes. Participants were assessed once, whereas if repeated preparations were performed there may have been trained efficiencies gained for each vaccine. PFS vaccines can greatly simplify the vaccine preparation process, allowing administrators to prepare almost four times more doses per hour than with vial and syringe systems.
Additional file 4: of Effects of community health volunteers on infectious diseases of children under five in Volta Region, Ghana: study protocol for a cluster randomized controlled trial
Creators: name: Yeonji Ma
name: Heunghee Kim
name: Yinseo Cho
name: Jaeeun Lee
name: Degley, Joseph
name: Abdul-Ghaffa Adam
name: Gyuhong Lee
name: Hoonsang Lee
name: Seungman Cha
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Computational Biology

description: Logical framework. (DOCX 24 kb)
Cost-effectiveness of add-on empagliflozin versus standard of care in management of CKD in Malaysia, Thailand and Vietnam – findings from a modelling study assessing an EMPA-KIDNEY eligible population, using CKD progression model.
Creators: name: Varghese, Lijoy
name: Chang, PohWan
name: Juntarasiripas, Sorrakorn
name: Pham, Hien
name: Uster, Anastasia
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Computational Biology

description: Background and objectives: Nearly one in ten individuals in South-East Asia are estimated to be affected by chronic kidney disease (CKD). The burden of end-stage kidney disease is significant and can be heavy on the healthcare system. The recent EMPA-KIDNEY trial demonstrated a significant reduction in the risk of kidney disease progression or cardiovascular death in patients with CKD with a broad range of kidney function using add-on empagliflozin versus standard of care (SoC) alone. The objective of this study was to estimate the economic benefit of empagliflozin for patients with CKD in Malaysia, Thailand and Vietnam. Methods: An individual patient level simulation model with an annual cycle that estimates the progression of kidney function and associated risk-factors was employed. Local costs and mortality rates were estimated from a wide range of published literature. A healthcare perspective was used over a 50-year time horizon. Results: The use of add-on empagliflozin versus SoC alone was found to be cost-saving in Malaysia and Thailand and cost-effective (ICER: 77,838,407 Vietnam Dong/QALY vs. a willingness to pay threshold of 96,890,026/QALY) in Vietnam. The bulk of the costs avoided over a lifetime is derived from the prevention or delay of dialysis initiation or kidney transplant – the cost offsets were nearly twice the additional treatment cost. The results were similar in patients with and without diabetes and across broad range of albuminuria. Conclusions: The use of add-on empagliflozin in a broad population of patients with CKD is expected to be cost-saving in Malaysia and Thailand and cost-effective in Vietnam and will help alleviate the increasing burden of CKD in the region.
Bolivaritettix brevipennis Deng, Zheng & Wei 2007
Creators: name: Deng, Wei-An
name: Zheng, Zhe-Min
name: Li, Xiao-Dong
name: Lin, Min-Ping
name: Wei, Shi-Zhen
name: Yuan, Bao-Dong
name: Lin, Li-Liang
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Bolivaritettix
Bolivaritettix brevipennis

description: 43. Bolivaritettix brevipennis Deng, Zheng & Wei, 2007
Specimens examined. 6 ♂ 4♀, Shangsi (Jiaoan), 21°54’N, 107°54’E, 400m alt, 19 Aug. 2012, collected by Wei- An DENG.
Distribution. China (Guangxi).
description: Published as part of Deng, Wei-An, Zheng, Zhe-Min, Li, Xiao-Dong, Lin, Min-Ping, Wei, Shi-Zhen, Yuan, Bao-Dong & Lin, Li-Liang, 2015, The groundhopper fauna (Orthoptera: Tetrigidae) of Shiwanshan (Guangxi, China) with description of three new species, pp. 151-178 in Zootaxa 3925 (2) on page 166, DOI: 10.11646/zootaxa.3925.2.1, http://zenodo.org/record/243557
Health care resource use and costs in patients with food allergies: a United States insurance claims database analysis
Creators: name: Sindher, Sayantani B.
name: Warren, Christopher
name: Ciaccio, Christina
name: Seetasith, Arpamas
name: Liu, Yutong
name: Gupta, Sachin
name: Gupta, Ruchi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy

description: Aims: Food allergies impose a large clinical and financial burden on patients and the health care system. However, little is known about the factors associated with health care resource use and costs. The aim of this study was to investigate health care resource use and costs in individuals with food allergies utilizing health care in the United States. Methods: We conducted a retrospective analysis of insurance claims data from the Merative™ MarketScan® Research Databases (indexed from January 1, 2015, to June 30, 2022). All-cause and food allergy-related health care resource use, direct medical, and out-of-pocket costs for medical services were estimated for 12 months post-index using International Classification of Diseases [ICD] codes. Results: Of 355,520 individuals with food allergies continuously enrolled in a health insurance plan for ≥12 months pre- and post-index, 17% had a food allergy-related emergency department visit and 0.9% were hospitalized. The top patient characteristics associated with all-cause and food allergy-related hospitalizations, all-cause costs, and food allergy-related outpatient visit costs was a Charlson Comorbidity Index score of ≥2. Food allergy-related direct medical and out-of-pocket costs were high among patients with a food allergy-related visit. Out-of-pocket cost per patient per year for outpatient visits, emergency department visits, and hospitalizations had an estimated mean of $1,631 for patients with food allergy-related visits, which is approximately 11% of the total costs for these services ($14,395 per patient per year). Limitations: Study limitations are primarily related to the nature of claims databases, including generalizability and reliance on ICD codes. Nevertheless, MarketScan databases provide robust patient-level insights into health care resource use and costs from a large, commercially insured patient population. Conclusion: The health care resource use of patients with food allergies imposes a burden on both the health care system and on patients and their families, especially if patients had comorbidities.