cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Reentrant Topological Phase Transition in a Bridging Model between Kitaev and Haldane Chains
Creators: name: Sugimoto, Takanori
name: Ohtsu, Mitsuyoshi
name: Tohyama, Takami
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We present a reentrant phase transition in a bridging model between two different topological models: Kitaev and Haldane chains. This model is activated by introducing a bond alternation into the Kitaev chain [A. Yu Kitaev, Phys.-Usp. {\bf 44} 131 (2001)]. Without the bond alternation, finite pairing potential induces a topological state defined by zero-energy Majorana edge mode, while finite bond alternation without the pairing potential makes a different topological state similar to the Haldane state, which is defined by local Berry phase in the bulk. The topologically-ordered state corresponds to the Su-Schrieffer-Heeger state, which is classified as the same symmetry class. We thus find a phase transition between the two topological phases with a reentrant phenomenon, and extend the phase diagram in the plane of the pairing potential and the bond alternation by using three techniques: recursive equation, fidelity, and Pfaffian. In addition, we find that the phase transition is characterized by both the change of the position of Majorana zero-energy modes from one edge to the other edge and the emergence of a string order in the bulk, and that the reentrance is based on a sublattice U(1) rotation. Consequently, our study and model do not only open a direct way to discuss the bulk and edge topologies, but demonstrate an example of the reentrant topologies.
description: 8 pages, 3 figures
Probiotic Potential of Pediococcus pentosaceus LJR1, a Bacteriocinogenic Strain Isolated from Rumen Liquor of Goat (Capra aegagrus hircus)
Creators: name: Gothandam Ladha
name: Kadirvelu Jeevaratnam
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: In present study, we evaluated the probiotic potential of three potent antibacterial Pediococcus pentosaceus isolates, viz., LJR1, LJR5, and LJR9 from the rumen liquor of a healthy goat and compared to a commercial probiotic, Lactobacillus rhamnosus GG NCDC 347. All the three isolates exhibited broad-spectrum of antibacterial activity against food borne pathogens. Among the isolates P. pentosaceus LJR1 strain was found to tolerate acid, bile, simulated gastric, and intestinal juice comparable to a standard strain and also showed strong adhesion to the human colon cancer (HCT-15) cells and prevented adhesion of Listeria monocytogenes. Furthermore, the P. pentosaceus LJR1 showed strong anti-inflammatory properties in the LPS-inflamed human peripheral blood mononuclear cells (PBMCs). The P. pentosaceus LJR1 showing potent antibacterial activity and all the desirable attributes of probiotic bacteria can be utilized as a candidate for the development of probiotic foods and deserves to be exploited for human and animal use.
title: Μία μη μαθηματική εισαγωγή στην κρυσταλλογραφία πρωτεϊνών
Creators: name: Glykos, Nikolaos
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΚΡΥΣΤΑΛΛΟΓΡΑΦΙΑ ΠΡΩΤΕΪΝΩΝ
ΚΡΥΣΤΑΛΛΟΓΡΑΦΙΑ
ΠΡΩΤΕΪΝΕΣ
ΔΟΜΗ ΠΡΩΤΕΪΝΩΝ
ΔΟΜΙΚΗ ΒΙΟΛΟΓΙΑ
ΒΙΟΦΥΣΙΚΗ
ΠΕΡΙΘΛΑΣΗ
ΜΟΡΙΑΚΗ ΒΙΟΛΟΓΙΑ
ΚΡΥΣΤΑΛΛΟΙ
PROTEIN CRYSTALLOGRAPHY
CRYSTALLOGRAPHY
PROTEINS
PROTEIN STRUCTURE
STRUCTURAL BIOLOGY
BIOPHYSICS
DIFFRACTION
MOLECULAR BIOLOGY
CRYSTALS

description: Η τεραστια πλειοψηφια των γνωστων δομων πρωτεινων και νουκλεικων οξεων -εικονες των οποιων εχουν κατακλυσει τα περισσοτερα συγγραμματα βιοχημειας, κυτταρικης και μοριακης βιολογιας- εχουν παραχθει με τη μεθοδο της κρυσταλλογραφιας ακτινων-Χ. Εξαιτιας του πλουσιου μαθηματικου υποβαθρου της μεθοδου, τα περισσοτερα συγγραματα αποφευγουν την παρουσιαση της μεθοδου, ή οταν το κανουν (για παραδειγμα, το τελευταιο κεφαλαιο απο το βιβλιο των Branden & Tooze), η παρουσιαση ειναι καπως αποσπασματικη και επιφανειακη. Αποτελεσμα αυτων ειναι οτι οι φοιτητες μενουν με μια μαλλον μυστικιστικη αισθηση-αντιληψη για μια μεθοδο που ειναι το θεμελιο της συγχρονης μοριακης βιολογιας, κατι που θα μπορουσαν να το συνοψισουν ως εξης : "... και ολη αυτη -η ατομικης διακριτικοτητας- πληροφορια για τη δομη και λειτουργια των πρωτεινων και των νουκλεικων εχει προκυψει απο κατι που λεγεται 'κρυσταλλογραφια' το οποιο ειναι τοσο μπερδεμενο και δυσκολο που καλυτερα να το αφησουμε εδω το θεμα".

Στοχος αυτου του βιβλιου-βοηθηματος ειναι -αποφευγοντας επιμελως τα μαθηματικα- να δειξει τις βασικες αρχες της κρυσταλλογραφιας πρωτεινων, δηλαδη το φυσικο νοημα του κρυσταλλογραφικου πειραματος. Τα μοναδικα προαπαιτουμενα των πρωτων κεφαλαιων του βιβλιου ειναι να εχουν οι φοιτητες καποιες αναμνησεις απο τη φυσικη του λυκειου και σχεδον τιποτα αλλο. Στα υστεροτερα κεφαλαια του βιβλιου γινεται αναφορα σε λιγα μαθηματικα, αλλα και αυτο τοσο προσεκτικα και αργα ωστε να ενας αποφασισμενος φοιτητης βιολογικου τμηματος να μπορει να τα παρακολουθησει. Το βοηθημα αυτο _δεν_ στοχευει να ειναι ενα συγγραμμα κρυσταλλογραφιας πρωτεινων, και δεν προσπαθει να καλυψει τα παντα απο direct methods, μεχρι solvent flattening και real space averaging. Μοναδικη φιλοδοξια του βιβλιου ειναι να αφαιρεσει το μυστικισμο που καλυπτει τη μεθοδο και να δειξει με απλο τροπο την ουσια του κρυσταλλογραφικου πειραματος χωρις να τρομοκρατησει με την μαθηματικη κρυσταλλογραφια.
title: ADCO, Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Cart. 29 (G 134), 996 folios, f. 0027
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0027, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Septième cartulaire de Saint-Étienne de Dijon (1661-1665), Archives départementales de la Côte-d'Or, Cart. 29 (G 134), 996 folios, f. 0027, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Simulating spiraling bubble movement in the EL approach
Creators: name: Weber, Andreas
name: Bart, Hans-Jörg
name: Klar, Axel
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Simulating the detailed movement of a rising bubble can be challenging, especially when it comes to bubble path instabilities. Free rising ellipsoidal bubbles not only move in straight lines but can describe sinusoidal, zigzag or spiraling paths. The common Euler Euler (EE) simulation techniques can no longer resolve the actual movement patterns and Direct Numerical Simulations (DNS) tend to be very costly when simulating a larger number of bubbles. A solution based on the Euler Lagrange (EL) approach is presented, where the bubbles show oscillating shape and/or instable paths while computational cost are at a far lower level than in DNS. The model calculates direction, shape and rotation of the bubbles to finally create typical instable path lines. This is embedded in an EL simulation, which can resolve bubble size distribution, mass transfer and chemical reactions. To ensure realistic solution, validation against experimental data of single rising bubbles and bubble swarms are presented. References with 2D and also 3D analysis are taken into account to compare simulative data in terms of typical geometrical parameters and average field values.
description: 18 pages, 11 figures, to be submitted to the Chemical Engineering Journal
Effect of Blending Various Biodiesels with Diesel on Performance and Emissions of Diesel Engine A Review
Creators: name: Rubiat Mustak
Publisher: name: figshare
Year: 2018
Subjects: subject: 91305 Energy Generation, Conversion and Storage Engineering
subject: FOS: Mechanical engineering
subject: 90607 Power and Energy Systems Engineering (excl. Renewable Power)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 90608 Renewable Power and Energy Systems Engineering (excl. Solar Cells)
subject: Mechanical Engineering

description: Due to limited resources and hazardous effects on environment people now a day tries to find out an alternative for fossil fuels. Fossil fuels when burnt produce a lot of carbon dioxide which is one of the primary reasons for global warming. Petroleum is a form of fossil fuel. With the help of distillation process petrol, paraffin, kerosene and diesel oil can obtain from natural petroleum. To protect the environment biodiesels can substitute these fossil fuels. Biodiesels can use as an alternative for diesel. Researchers from around the world tried for many years to find a suitable biodiesel which can substitute diesel. Many biodiesels have been produced from different sources and tested for their performances. Some researchers try to find out a good combination of biodiesel blends which can be used as an alternative of diesel. Some of them try to find out a suitable blend of diesel and biodiesel to reduce the environmental impact and for better emission characteristics. Effects of blending different types of biodiesels with diesel have been investigated by many researchers. In this present review article a summary is written on such attempts.
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0510
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0510, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0510, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
The Jones polynomial of an almost alternating link
Creators: name: Lowrance, Adam M.
name: Spyropoulos, Dean
Publisher: name: arXiv
Year: 2017
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 57M27 (Primary), 57M25 (Secondary)

description: A link is almost alternating if it is non-alternating and has a diagram that can be transformed into an alternating diagram via one crossing change. We give formulas for the first two and last two potential coefficients of the Jones polynomial of an almost alternating link. Using these formulas, we show that the Jones polynomial of an almost alternating link is nontrivial. We also show that either the first two or last two coefficients of the Jones polynomial of an almost alternating link alternate in sign. Finally, we describe conditions that ensure an almost alternating diagram has the fewest number of crossings among all almost alternating diagrams of the link.
description: 24 pages, 16 figures; minor changes throughout
Deliverable 3.2 - Cost Estimate
Creators: name: Giberti, Luca
name: Grillo, Vincenzo
name: Rotunno, Enzo
name: De Jong, Frank
name: Tiemeijer, Peter
name: Dona, Pleun
name: Roncaglia, Alberto
name: Belsito, Luca
Publisher: name: Zenodo
Year: 2022

description: This deliverable itemises and details the elements for MINEON products and defines the prospective costs
 as a function of the production volumes.
 In the first chapter the MINEON product is described in general.
 In the second chapter the items are described to a better level of detail making also a comparison with
 potentially similar products on the market.
 In the third chapter the costs are discussed in detail in different scenarios.
 In the final chapter the conclusions are drawn.
Mean first passage time of active Brownian particle in one dimension
Creators: name: Scacchi, Alberto
name: Sharma, Abhinav
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We investigate the mean first passage time of an active Brownian particle in one dimension using numerical simulations. The activity in one dimension is modeled as a two state model; the particle moves with a constant propulsion strength but its orientation switches from one state to other as in a random telegraphic process. We study the influence of a finite resetting rate $r$ on the mean first passage time to a fixed target of a single free Active Brownian Particle and map this result using an effective diffusion process. As in the case of a passive Brownian particle, we can find an optimal resetting rate $r^*$ for an active Brownian particle for which the target is found with the minimum average time. In the case of the presence of an external potential, we find good agreement between the theory and numerical simulations using an effective potential approach.
description: 5 pages, 4 figures
A medical orderly in the Navy
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Arthur George Vowles was born on 3rd March 1920 in Bow, London. He joined the Navy in 1938 when he was 18 years old. He became a medic in the Navy, being shore based in a Naval hospital. He spent a lot of time in Egypt and Eritrea. In Eritrea he helped to build a road, which the Italians bombed. He also built an incinerator to burn bandages etc. He spent time on the Ark Royal and Indomitable.On leaving the Navy, he became a Prison Officer.
Method to measure efficiently rare fluctuations of turbulence intensity for turbulent-laminar transitions in pipe flows
Creators: name: Nemoto, Takahiro
name: Alexakis, Alexandros
Publisher: name: arXiv
Year: 2017
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The fluctuations of turbulence intensity in a pipe flow around the critical Reynolds number is difficult to study but important because they are related to turbulent-laminar transitions. We here propose a rare-event sampling method to study such fluctuations in order to measure the time-scale of the transition efficiently. The method is composed of two parts: (i) the measurement of typical fluctuations (the bulk part of an accumulative probability function) and (ii) the measurement of rare fluctuations (the tail part of the probability function) by employing dynamics where a feedback control of the Reynolds number is implemented. We apply this method to a chaotic model of turbulent puffs proposed by Barkley and confirm that the time-scale of turbulence decay increases super-exponentially even for high Reynolds numbers up to Re = 2500, where getting enough statistics by brute-force calculations is difficult. The method uses a simple procedure of changing Reynolds number that can be applied even to experiments.
description: 12 pages, 9 figures
Childhood Memories of the War - Diana Esme Wooldridge
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Diana was born in 1938, the youngest of four children. They lived in Littlehampton and Diana remembers lots of Canadian and American soldiers in the area. The troops were billeted in large houses. She remembers being taken to see a bombed house, where she a body lay twitching. She also remembers seeing a dog fight above where she was sitting under a tree with her mother. Near Pier Road, she saw a body floating in the river. Diana also remembers a line of vehicles, perhaps lining up for D-Day and waves of planes going over. The soldiers took a local dog with them. An unexploded bomb was found in their garden and her mum had to find somewhere else to live, with her four children. She found a large house and they had ten marine commanders billeted with them, practising in the Arun. Later she had Air Sea Rescue billeted in the house. Peter and Stella, her siblings were evacuated to Nottingham. Diana and her other brother, Robert stayed in Littlehampton with her mum. On VE Day Stella, Diana's mum arranged a street party for everyone. Diana's father was in the Royal Marines. He manned a machine gun at Admiralty Arch.
3 Wartime Stories from 1 Descendant
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Story 1 - As Aircraft Ground Crew in EgyptMy father, Alfred Henry Baker, was 16 when the war started and was evacuated to St Neots. He was very well looked after by the family he was lodged with and remained friends with them after the war. When he returned to London from St Neots, he was a Fire Watch volunteer in London, directing firemen to the location of fires. He joined the RAF in 1941 when he turned 18. He wanted to be a pilot but wasn't accepted and became ground crew. He was sent to Egypt, to a place called Halwen, which is near Cairo, because there are photos of the Pyramids when he was off duty. He was also able to visit the Holy Land during his leave. He told me that he worked on aircraft maintenance, in particular on radios and that they had to do a lot of cleaning of sand and dust out of the aircraft equipment. He made good friendships in the Air Force, and many remained lifelong friends.Story 2 - Poetry from a Prisoner of WarMy uncle, Denis Webb, was my mother's brother. He was called up in January 1940. He hated the war and never spoke about it. He was captured on the Continent, and imprisoned in Germany for three and a half years. While he was a prisoner of war, he wrote a poem and sent it home. My grandmother kept it.Story 3 -  Life on the Home FrontMy mother was Joyce Evelyn Baker. When she passed away, I wrote details of memories of her life. Excerpts from those notes are included on the Object List.
Learning from Misconceptions: Catalogs of C and Python Antipatterns by CS1 Students
Creators: name: Blind Blind
Publisher: name: Zenodo
Year: 2020

description: In this dataset we present the following artifacts: Antipatterns that occurred in both languages; Antipatterns that occurred exclusively in each programming language; List of exercises analyzed to extract the antipatterns and a guideline for instructors and students on how they can use it.
Childhood Memories of the War - Isobel Fyfe
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Isobel was born in 1936 and lived in Aberdeen throughout the war (and during the Aberdeen Blitz). She has provided her own narrative of her experiences and also a copy of a poem she wrote 'Aberdeen VE day 8th May 1945'.
The Euclidean distance degree of smooth complex projective varieties
Creators: name: Aluffi, Paolo
name: Harris, Corey
Publisher: name: arXiv
Year: 2017
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14C17

description: We obtain several formulas for the Euclidean distance degree (ED degree) of an arbitrary nonsingular variety in projective space: in terms of Chern and Segre classes, Milnor classes, Chern-Schwartz-MacPherson classes, and an extremely simple formula equating the Euclidean distance degree of X with the Euler characteristic of an open subset of X.
The Challenges and Opportunities in Delivering Large Language Models to Australian Researchers
Creators: name: Sinnott, Richard
Publisher: name: Zenodo
Year: 2024
Subjects: Machine Learning
Tools
Software
Deep Learning
Engagement
Infrastructure
Data
AI

description: Large language models (LLMs) such as chatGPT have the potential to massively augment the way in which research is conducted. The Melbourne eResearch Group at The University of Melbourne (www.eresearch.unimelb.edu.au) have been exploring LLMs and the capabilities they can bring for over a year. This presentation will introduce LLMs and the practical challenges that are faced in hosting and operating production level LLM capabilities for the broader research community. Specifically the talk will cover:

 the benefits of direct deployment and hosting of LLMs, i.e. rather than direct use of the openAI API;
 the opportunities of LLMs with example case studies in their use;
 the challenges of hosting LLMs on national Cloud platforms such as NeCTAR and the demands this gives rise to on the underpinning technologies and hardware;
 supporting current and future LLM deployments and the technological requirements this gives rise to.

The talk will focus especially on the NeCTAR Cloud-based deployment of LLAMA3 and Mistral (https://kalliope.pages.gitlab.unimelb.edu.au/chat/)   two open sources LLMs.
Flight Lieutenant Tony Hayter from the Great Escape
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: For the whole time Fl Lt Tony Hayter was in the RAF he wrote regular letters to his girlfriend, Cynthia Henstock, whom he clearly hoped to marry one day. These started with his initial training, then on to the Middle East and finally from Stalag Luft III.They describe quite a dull uneventful life but the reality was very different. He was shot down over Sicily in 1942 and taken to Stalag Luft III in Poland. Once there it seems he was immediately involved in preparations for the "Great Escape". He started giving German lessons, he was also attending lectures on navigation.The breakout took place in 1944 but sadly he was one of the people recaptured, and one of the 50 who were shot. There is now a memorial to those men at the site of the camp.
PCSK9 inhibitors: a non-statin cholesterol-lowering treatment option
Creators: name: Pokrywka, Gregory S.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Elevated low-density lipoprotein cholesterol (LDL-C) plays a major role in the development of atherosclerotic cardiovascular disease. Statins are the first-line treatment to lower LDL-C in patients with hypercholesterolemia; however, some high cardiovascular risk patients may have inadequate responses to statin therapy or are intolerant to statins, and may need additional and/or alternative non-statin therapies to further reduce their LDL-C levels. Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9), a key regulator of circulating LDL-C levels, have received considerable attention as promising non-statin therapeutic options for the management of hypercholesterolemia. This review provides a brief overview of the history and science of PCSK9 inhibitors, focusing on two PCSK9 monoclonal antibodies that have been approved by the US Food and Drug Administration: alirocumab and evolocumab. Recently released and forthcoming clinical trial data will be discussed, as well as the practical application of patient populations that may benefit from PCSK9 inhibitors. Finally, the recent expert recommendations regarding the use of PCSK9 inhibitors and other non-statin therapies to treat patients with inadequate LDL-C-lowering on statin therapy will be summarized.
Additional file 2: of A panel of DNA methylation markers for the detection of prostate cancer from FV and DRE urine DNA
Creators: name: Brikun, Igor
name: Nusskern, Deborah
name: Decatus, Andrew
name: Harvey, Eric
name: Li, Lin
name: Freije, Diha
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Genomic sequences for CpG islands listed alphabetically. (DOCX 40 kb)
On the domain of elliptic operators defined in subsets of Wiener spaces
Creators: name: Addona, D.
name: Cappa, G.
name: Ferrari, S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Analysis of PDEs (math.AP)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 28C20, 35J15, 46G12, 47A07, 47A30

description: Let $X$ be a separable Banach space endowed with a non-degenerate centered Gaussian measure $μ$. The associated Cameron-Martin space is denoted by $H$. Consider two sufficiently regular convex functions $U:X\rightarrow\mathbb{R}$ and $G:X\rightarrow \mathbb{R}$. We let $ν=e^{-U}μ$ and $Ω=G^{-1}(-\infty,0]$. In this paper we are interested in the domain of the the self-adjoint operator associated with the quadratic form \begin{gather} (ψ,φ)\mapsto \int_Ω\langle\nabla_Hψ,\nabla_Hφ\rangle_Hdν\qquadψ,φ\in W^{1,2}(Ω,ν).\qquad\qquad (\star) \end{gather} In particular we obtain a complete characterization of the Ornstein-Uhlenbeck operator on half-spaces, namely if $U\equiv 0$ and $G$ is an affine function, then the domain of the operator defined via $(\star)$ is the space \[\{u\in W^{2,2}(Ω,μ)\,|\, \langle\nabla_H u(x),\nabla_H G(x)\rangle_H=0\text{ for }ρ\text{-a.e. }x\in G^{-1}(0)\},\] where $ρ$ is the Feyel-de La Pradelle Hausdorff-Gauss surface measure.
description: arXiv admin note: text overlap with arXiv:1609.07337
Anyonic quasiparticles of hardcore anyons
Creators: name: Wildeboer, Julia
name: Patra, Aniket
name: Manna, Sourav
name: Nielsen, Anne E. B.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Strongly interacting topologically ordered many-body systems consisting of fermions or bosons can host exotic quasiparticles with anyonic statistics. This raises the question whether many-body systems of anyons can also form anyonic quasiparticles. Here, we show that one can, indeed, construct many-anyon wavefunctions with anyonic quasiparticles. The braiding statistics of the emergent anyons are different from those of the original anyons. We investigate hole type and particle type anyonic quasiparticles in Abelian systems on a two-dimensional lattice and compute the density profiles and braiding properties of the emergent anyons by employing Monte Carlo simulations.
description: 9 pages, 4 figures, v4: Accepted version
Superthermal light emission and nontrivial photon statistics in small lasers
Creators: name: Wang, T.
name: Aktas, D.
name: Alibart, O.
name: Picholle, É.
name: Puccioni, G. P.
name: Tanzilli, S.
name: Lippi, G. L.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Photon statistical measurements on a semiconductor microlaser, obtained using single-photon counting techniques, show that a newly discovered spontaneous pulsed emission regime possesses superthermal statistical properties. The observed spike dynamics, typical of small-scale devices, is at the origin of an unexpected discordance between the probability density function and its representation in terms of the first moments, a discordance so far unnoticed in all devices. The impact of this new dynamics is potentially large, since coincidence techniques are presently the sole capable of characterizing light emitted by nanolasers.
description: 11 pages, 8 figures
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Cart. 190 (11 H 75), 316 folios, f. 0271r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0271r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VI, Archives départementales de la Côte-d'Or, Cart. 190 (11 H 75), 316 folios, f. 0271r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Zooplankton adrift: investigating transportation by cyclonic eddy
Creators: name: Lecea, Ander M. De
name: Coppin, Ross
name: Noyon, Margaux
name: Huggett, Jenny A.
Publisher: name: Taylor & Francis
Year: 2018
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry

description: Eddies are important not just because they have momentum and can transfer water properties, but also because they play an important role in increasing the trophic energy available to organisms, thereby enhancing primary productivity. This study was conducted to test the ‘suitcase hypothesis’ – the inclusion of organic matter (OM), plankton and larvae within the single water mass of an eddy, which are then highly conserved and transported to another location. Here we hypothesize that particulate OM (POM) and zooplankton from the continental shelf of Madagascar become trapped as the eddy forms and are transported westwards. We analysed stable isotope signatures of POM and zooplankton from samples collected from the continental shelf (CS) as well as within an eddy that had recently formed off the south-west coast of Madagascar. There was no statistical difference in the POM isotopic signature or C/N ratios between the continental shelf or any of the eddy regions. However, some C/N ratio values could suggest that some OM from close to the coastal region could have been transported by the eddy. This was not the case for zooplankton, however, with isotopic signatures on the CS greatly differing from those in the eddy. Several factors could account for these differences including feeding behaviour or tissue turnover rate. We conclude that our study did not gather enough evidence to support (or reject) the ‘suitcase’ hypothesis, and further studies are needed in order to fully understand the transport of material, including zooplankton and larvae, by eddies.
Sergeant Les Brooks's Letters and Documents
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Sergeant Len Brooks was in the 77 Squadron at RAF Driffield and flew Whitley bombers. He was born 9/4/17, died 28/5/40. He joined up in 1938.
He was shot down. Len's nephew supplied many letters documenting the social history at the time and his uncle's death (see object list) - no other details or dates.
In situ characterization of phase separation in PVP dextran solutions using impedance spectroscopy
Creators: name: Smith, Geoffrey
name: Ermolina, Irina
Publisher: name: De Montfort University
Year: 2023
Subjects: classificationCode: 321405
subject: Pharmaceutical sciences

description: cite as :
Arshad, M.S., Smith, G.S., Polygalov, E., Ermolina, I., Page, T., Taylor, Birkmire, A. (2013) In situ characterization of phase separation in PVP dextran solutions using impedance spectroscopy. AAPS annual meeting and exposition. San Diego, November 10th – 14th. Poster Presentation on November 12th
This poster described the first time that through-vial impedance spectroscopy (TVIS) has been used to study the phase separation of two formulation additives used in certain freeze-dried drug product solutions.
title: ADCO, Grènetier de Cîteaux : comptes (1497-1504) (11 H 1172), f. 00303
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes

description: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172), f. 00303, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Security and Information
Creators: name: Victoria, Artur
Publisher: name: Zenodo
Year: 2020
Subjects: nformation,security,

description: With the argument that society needs to have certain products and / or services, the constituted powers create public bodies that are properly structured to act in a certain line of activity, such as education, security, health, social welfare, etc. In this way, they provide products and / or services directly to the population, who pay for them by collecting taxes. With the emergence of mixed economy companies providing computer services it is no different from other public bodies, as they are entities created out of the interests of the members of a Government and aim, in principle, at the conception of a business model that encourages the scientific and technological development within the scope of Public Administration. Due to their legal nature, they must necessarily seek organizational performance, translated into rates of return on investments made. To do this, they must sell products and / or services directly to public bodies and entities, which can use them in their strategic, tactical and operational activities. With this, directly or indirectly, the population will also be paying and benefiting from them, since they will be able to use them via public agencies. Society demands from governments more and more smoothness and ethics in the treatment of public resources. When the Government chooses a group of managers to lead the direction of a mixed economy company providing computer services for a given term, the strategic decisions of those managers become important for all members of the organization, shareholders and mainly for society. Thus, it is hoped that the decisions made can contribute to the achievement of the organization's financial health, customer satisfaction and social well-being.
title: Achaemenid Persia: Images and Memory at Rome (205 BCE – 115CE)
Creators: name: Serena, Mauro
Publisher: name: University of Reading
Year: 2020

description: This thesis explores the Roman perception of Achaemenid Persia. It investigates how they came in contact with the Greek cultural memory of the Persian East, how they acquired and reused it and, in the process, they created their own original memories of Persia. The work focusses on three instances of appropriation and the context within which they occur in order to understand by what forces they were prompted. First, it shows how the clash with Mithridates, territorial expansion and internal rivalry in the Late Republic promote the creation of a complex image of Persia as a symbol of triumph and victory over external enemies and internal political adversaries. Then, it sets the appropriation of the Athenian memory of the Persian Wars within the context of the transformation of the Republic into the principate and the subtle ideological and political manoeuvring that accompanied it. Finally, it argues that in a new Roman world in which the power is transferred from the aristocracy to the princeps, Persia, or, more precisely, the Persian kings, becomes a point of interest providing opportunities for those interested in exploring the idea of autocracy. The Persian ruler becomes a yardstick against which to gauge the tyranny of the emperor and, as such, he is used by Seneca the Younger to build figure of archetypical despot: the emperor Gaius. The dissertation contends that the Roman reworking of Persian memories produced a a new perception of Persia which closely reflects the evolution of the power dynamic of Roman policy.
D-brane Disformal Coupling and Thermal Dark Matter
Creators: name: Dutta, Bhaskar
name: Jimenez, Esteban
name: Zavala, Ivonne
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Conformal and Disformal couplings between a scalar field and matter occur naturally in general scalar-tensor theories. In D-brane models of cosmology and particle physics, these couplings originate from the D-brane action describing the dynamics of its transverse (the scalar) and longitudinal (matter) fluctuations, which are thus coupled. During the post-inflationary regime and before the onset of big-bang nucleosynthesis (BBN), these couplings can modify the expansion rate felt by matter, changing the predictions for the thermal relic abundance of dark matter particles and thus the annihilation rate required to satisfy the dark matter content today. We study the D-brane-like conformal and disformal couplings effect on the expansion rate of the universe prior to BBN and its impact on the dark matter relic abundance and annihilation rate. For a purely disformal coupling, the expansion rate is always enhanced with respect to the standard one. This gives rise to larger cross-sections when compared to the standard thermal prediction for a range of dark matter masses, which will be probed by future experiments. In a D-brane-like scenario, the scale at which the expansion rate enhancement occurs depends on the string coupling and the string scale.
description: 28 pages, 12 figures. Version to appear in PRD. Minor changes, typos corrected and reference added
title: Ειδική παθολογία πεπτικού συστήματος του χοίρου
Creators: name: Papatsiros, Vasileios
Publisher: name: Kallipos, Open Academic Editions
Year: 2016
Subjects: ΧΟΙΡΟΣ
ΠΑΘΟΛΟΓΙΑ
ΔΙΑΧΕΙΡΙΣΗ ΤΗΣ ΥΓΕΙΑΣ
ΠΕΠΤΙΚΟ ΣΥΣΤΗΜΑ
ΝΟΣΗΜΑΤΑ
ΛΟΙΜΩΞΕΙΣ
Pig
Swine
Medicine
Pathology
Porcine Heard Health Management
Digestive System
Diseases
Infections

description: Το προτεινόμενο σύγγραμμα θα αναφέρεται σε γενικά στοιχεία της παθοφυσιολογίας και ανοσολογίας του πεπτικού συστήματος του χοίρου και ειδικότερα σε νοσήματα και παθολογικές καταστάσεις, στην αιτιολογία των οποίων εμπλέκονται βακτήρια, ιοί, παράσιτα και διάφοροι διαχειριστικοί παράγοντες (π.χ. σφάλματα διατροφής, μεταχείριση ζώων, συνθήκες διαβίωσης, περιβαλλοντικοί παράγοντες κ.α.)
Ειδικότερα, γίνεται αναφορά στην αιτιοπαθογένεια, στην κλινική εικόνα, στη διάγνωση, στην αντιμετώπιση σε επίπεδο θεραπείας και μεταφύλαξης καθώς και στην προφύλαξη - πρόληψη. Πιο συγκεκριμένα, η προφύλαξη και η μεταφύλαξη των νοσημάτων επικεντρώνεται κυρίως στην επιλογή των κατάλληλων φαρμακευτικών και μη ουσιών (π.χ. αντιμικροβιακά φάρμακα, εναλλακτικά των αντιβιοτικών κ.α.), τον τρόπο χορήγησής τους καθώς και την εφαρμογή των απαραίτητων εμβολιακών προγραμμάτων.
Neutron star dynamics under time dependent external torques
Creators: name: Gügercinoğlu, Erbil
name: Alpar, M. Ali
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The two component model describes neutron star dynamics incorporating the response of the superfluid interior. Conventional solutions and applications involve constant external torques, as appropriate for radio pulsars on dynamical timescales. We present the general solution of two component dynamics under arbitrary time dependent external torques, with internal torques that are linear in the rotation rates, or with the extremely non-linear internal torques due to vortex creep. The two-component model incorporating the response of linear or nonlinear internal torques can now be applied not only to radio pulsars but also to magnetars and to neutron stars in binary systems, with strong observed variability and noise in the spin-down or spin-up rates. Our results allow the extraction of the time dependent external torques from the observed spin-down (or spin-up) time series, $\dotΩ(t)$. Applications are discussed.
description: Accepted by MNRAS
Insights into the catalytic mechanism of ligninolytic peroxidase and laccase in lignin degradation
Creators: name: Bhatt, Pankaj
name: Tiwari, Meena
name: Parmarick, Prasoon
name: Bhatt, Kalpana
name: Gangola, Saurabh
name: Adnan, Muhammad
name: Singh, Yashpal
name: Bilal, Muhammad
name: Ahmed, Shakeel
name: Chen, Shaohua
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Virology
subject: Computational Biology

description: The present study aimed to give insights into the binding interactions of the laccases and peroxidase for the degradation of the lignin. The active site of the applied enzymes contains the amino acids that are playing an essential role in lignin degradation. The binding pocket amino acids have interacted with the lignin via the hydrogen, alkyl and van der Waal bonds. The mutagenesis in the active sites of these enzymes predicted the increasing and decreasing performance of the lignin-degrading enzymes. Ramachandran plot analysis of the Laccase and peroxidases determined the active conformation of the lignin-degrading enzymes. Phylogenetic study of the Laccase, lignin peroxidase, versatile peroxidase and manganese peroxidase suggested each of the enzymes belong to the separate protein cluster. The present study reveals the binding potential of the various lignin-degrading enzymes that could increase our understanding of the application of plant biomass large scales.
Bright X-ray radiation from plasma bubbles in an evolving laser wakefield accelerator
Creators: name: Bloom, M. S.
name: Streeter, M. J. V.
name: Kneip, S.
name: Bendoyro, R. A.
name: Cheklov, O.
name: Cole, J. M.
name: Doepp, A.
name: Hooker, C. J.
name: Holloway, J.
name: Jiang, J.
name: Lopes, N. C.
name: Nakamura, H.
name: Norreys, P. A.
name: Rajeev, P. P.
name: Symes, D. R.
name: Schreiber, J.
name: Wood, J. C.
name: Wing, M.
name: Najmudin, Z.
name: Mangles, S. P. D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We show that the properties of the electron beam and bright x-rays produced by a laser wakefield accelerator can be predicted if the distance over which the laser self-focuses and compresses prior to self-injection is taken into account. A model based on oscillations of the beam inside a plasma bubble shows that performance is optimised when the plasma length is matched to the laser depletion length. With a 200~TW laser pulse this results in an x-ray beam with median photon energy of \unit[20]{keV}, $> 6\times 10^{8}$ photons above \unit[1]{keV} per shot and a peak brightness of $\unit[3 \times 10^{22}]{photons~s^{-1}mrad^{-2}mm^{-2} (0.1\% BW)^{-1}}$.
description: 5 pages, 4 figures
Country Parish (near Rochester) Rector's Wartime Life
Creators: name: Project Team, Their Finest Hour
Publisher: name: University of Oxford
Year: 2024
Subjects: classificationCode: 430304
subject: British history
classificationCode: 430308
subject: European history (excl. British, classical Greek and Roman)
classificationCode: 430316
subject: International history

description: Stanley Howard, David's father, was the rector of a country parish near Rochester in Kent. David was born in 1944 and on one occasion when his pram had been left outside the house a doodlebug came close to hitting it. Stanley was an ARP warden looking for doodlebug fires in the local area. Stanley had an interesting document (not supplied) from the Government stating that he would be an emergency contact from the Ministry of Food. In the backyard, the family kept chickens, which supplied them with eggs. There was a little area called 'the Glebe' where they grew potatoes, peas etc. Stanley kept a parish newsletter.