cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: of From policy to practice: exploring the implementation of antiretroviral therapy access and retention policies between 2013 and 2016 in six sub-Saharan African countries
Creators: name: Ambia, Julie
name: Renju, Jenny
name: Wringe, Alison
name: Todd, Jim
name: Geubbels, Eveline
name: Nakiyingi-Miiro, Jessica
name: Urassa, Mark
name: Lutalo, Tom
name: Crampin, Amelia
name: Kwaro, Daniel
name: Kyobutungi, Catherine
name: Natsayi Chimbindi
name: F. Gomez-Olive
name: Malebogo Tlhajoane
name: Njamwea, Brian
name: Basia Zaba
name: Mee, Paul
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A description of policies for increasing ART access and improving retention in care by country and date of adoption. (DOCX 28 kb)
Additional file 1: of Development of guidelines for giving community presentations about eating disorders: a Delphi study
Creators: name: Doley, Joanna
name: Hart, Laura
name: Stukas, Arthur
name: Morgan, Amy
name: Rowlands, Danielle
name: Paxton, Susan
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Complete list of items endorsed or not endorsed by questionnaire round. Table S1. Items endorsed in round one by scale and panel group (% agreement). Table S2. Items endorsed in round two by scale and panel group (% agreement). Table S3. Items endorsed in round three by scale and panel group (% agreement). Table S4. Items not endorsed in round one by scale and panel group (% agreement). Table S5. Items not endorsed in round two by scale and panel group (% agreement). Table S6. Items not endorsed in round three by scale and panel group (% agreement). (PDF 247 kb)
Chrysoprasis tendira Napp & Martins 1998
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Chrysoprasis
Chrysoprasis tendira

description: 11. Chrysoprasis tendira Napp & Martins, 1998: 470, figs. 3, 29 Holotype, male
Type locality. Brazil, Mato Grosso: Cáceres, 04.XII.1984, C. Elias
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 343, DOI: 10.5281/zenodo.250291
Center for Frontiers in High Energy Density Science
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The Center for Frontiers in High Energy Density Science (HEDS) is a strategic partnership between the University of California and Department of Energy (DOE) Laboratories to transform the scientific and educational foundations of HED science. HEDS is a multidisciplinary approach to understanding the fundamental processes that govern material properties and physical processes under extreme conditions of temperature, pressure, and compression rate. The proposed research program spans understanding highly compressed materials in planetary interiors to energy transport processes relevant to inertial confinement fusion and astrophysical plasmas. The Center will enable deep collaborations between UC and DOE scientists and leverage advanced target designs and diagnostics, high performance computing, and significant facility investments made by DOE at Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL). This partnership positions the Center to advance understanding of complex material states in the HED regime (>1 Mbar pressure) and investigate the fundamental mechanisms that control material strength and energy transport processes. By applying our advances in understanding HED matter to high-profile problems in planetary science and fusion energy, our team will advance fundamental knowledge and attract young scientists to the field. The challenges faced in understanding HED matter reach beyond traditional disciplinary boundaries and require a novel approach to recruitment, education and training in HEDS. Our team of leading HED scientists will develop a core HED curriculum across the UC system that crosscuts the major disciplines that serve as entry to HEDS and offer targeted, intensive summer schools. The Center will mentor students and postdocs, who will be trained through hands-on research experiences in collaboration with DOE scientists. The Center will enable transformative research and technical development by novel use of DOE facilities, unique research and technical collaborations between UC and DOE scientists, and deepening connections between theory, experiment, computation and applications. UC will be positioned to lead future, larger initiatives in HEDS. Ultimately, the Center will have an impact on society, from expanding basic knowledge and education to enabling new advances in energy and supporting national security.
Strongly correlated surface states
Creators: name: Alexandrov, Victor A.
Publisher: name: No Publisher Supplied
Year: 2014

description: Everything has an edge. However trivial, this phrase has dominated theoretical condensed matter in the past half a decade. Prior to that, questions involving the edge considered to be more of an engineering problem rather than a one of fundamental science: it seemed self-evident that every edge is different. However, recent advances proved that many surface properties enjoy a certain universality, and moreover, are 'topologically' protected. In this thesis I discuss a selected range of problems that bring together topological properties of surface states and strong interactions. Strong interactions alone can lead to a wide spectrum of  emergent phenomena: from high temperature superconductivity to unconventional magnetic ordering; interactions can change the properties of particles, from heavy electrons to fractional charges. It is a unique challenge to bring these two topics together.      The thesis begins by describing a family of methods and models with interactions so high that  electrons effectively disappear as particles and new bound states arise.  By invoking the AdS/CFT correspondence we can mimic the physical systems of interest as living on the surface of a higher dimensional universe with a black hole. In a specific example we investigate the properties of the surface states and find helical spin structure of emerged particles.      The thesis proceeds from helical particles on the surface of black hole to a surface of samarium hexaboride: an f-electron material with localized magnetic moments at every site. Interactions between electrons in the bulk lead to insulating behavior, but the surfaces found to be conducting. This observation motivated an extensive research: weather the origin of conduction is of  a topological nature. Among our main results, we confirm theoretically the topological properties of SmB6;  introduce a new framework to address similar questions for this type of insulators, called Kondo insulators. Most notably we introduce the idea of Kondo band banding (KBB): a modification of edges and their properties due to interactions. We study (chapter 5) a simplified 1D Kondo model, showing that the topology of its ground state is unstable to KBB.  Chapter 6 expands the study to 3D: we argue that not only KBB preserves the topology but it could also explain the experimentally observed anomalously high Fermi velocity at the surface as the case of large KBB effect.
Regulation of Breast Epithelial Cell Motility by Proteases
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Breast cancer is lethal because cancer cells are able to invade the surrounding tissues. Eventually, these cells grow at distant sites, and the spread of breast cancer throughout the body becomes life threatening. If one could prevent cancer cells from invading, breast cancer would remain confined and could conceivably be cured by surgical removal of the initial cancerous lesions. Our interest is focused on the very early step of cancer cell invasion, its crossing of the basement membrane. In the normal breast gland, the basement membrane keeps the breast epithelial cells neatly organized in functional structures. Importantly, it keeps them separated from the underlying connective or fat tissues. At early stages, even breast cancer cells are effectively segregated from surrounding tissues by the basement membrane. This is recognized clinically as carcinoma in situ. A critical transition in the development of breast cancer occurs when cancer cells no longer respect the boundary represented by the breast gland basement membrane. Once they invade the underlying tissues, cancer cells have made the first step to spread to the rest of the body. The transition to invading cells is unpredictable in all cancers, but particularly so in breast cancer. Therefore, there are several important questions to be addressed. What motivates cancer cells to cross the basement membrane? What are the mechanisms that make normal cells respect the basement membrane boundary? How do these mechanisms break down in invading breast cancer? An answer to these questions will form a foundation for novel treatment of breast cancer, specifically aimed at blocking cancer cell invasion and spread (metastasis).

 With this proposal, we hope to identify one mechanism of breast cancer cell invasion, which may represent a target for drug discovery. We found that a substance called protease MMP2 acts upon a constituent of the basement membrane, called laminin-5 (Ln-5), and changes it into a stimulant for cell invasion. We showed that breast cells like to adhere to Ln-5 and stay put. In contrast, if breast cells come in contact with Ln-5 that has been modified by the protease MMP2, they become highly motile. It is perhaps more than a coincidence that, in tissue specimens from patients, MMP2 is often found concentrated along sites where breast cancer cell invasion occurs. We believe this phenomenon reflects a mechanism whereby MMP2 stimulates cancer cells to invade by activating a function on Ln-5 that makes cells move around. The basic knowledge about the breast obtained from these studies may form the basis for novel approaches for designing drugs that can stop breast cancer cells from spreading, even at advanced stages.
Additional file 1: of Are identities oral? Understanding ethnobotanical knowledge after Irish independence (1937–1939)
Creators: name: Shannon, Fiona
name: Sasse, Astrid
name: Sheridan, Helen
name: Heinrich, Michael
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Plant Biology
subject: 60506 Virology

description: Plant citing’s from participants’ oral recollections and their personal contributions documented in the SMC. It is a table of the plant species cited by participants’ and documented in the archives. It includes details on vernacular name, plant family, diseases treated and species origin. (PDF 30 kb)
THE ROLE AND IMPORTANCE OF GOLDSMITHING AND EMBROIDERY IN NATIONAL CRAFTS IN SCHOOL CIRCLES
Creators: name: Navbahor Eshinxoʻjayeva
Publisher: name: Zenodo
Year: 2024

description: This article explores the role and importance of goldsmithing and embroidery in national crafts within school circles. These traditional crafts not only preserve cultural heritage but also provide students with practical skills and creative outlets. By integrating goldsmithing and embroidery into educational curricula, schools can foster a deeper appreciation for national craftsmanship and promote the development of fine motor skills, artistic expression, and cultural awareness among students. The study highlights various methods and benefits of teaching these crafts in school settings, including enhancing student engagement, promoting cultural identity, and supporting local economies through the continuation of traditional practices..
Design and synthesis of prostate specific antigen-activated prodrugs
Creators: name: Aloysius, Herve
Publisher: name: No Publisher Supplied
Year: 2014

description: The feasibility of targeted delivery of cytotoxic agents to prostate cancer cells via selective activation of peptide-linked prodrugs by prostate-specific antigen (PSA) has been previously demonstrated. PSA is a chymotryspin-like serine protease that uniquely cleaves after Gln. Using cleavage maps for its natural substrates, semenogelins I and II, the highly specific PSA substrate glutaryl-Hyp-Ala-Ser-Chg-Gln was discovered, and subsequently coupled to various cytotoxic agents as a promoiety to synthesize prodrugs with enhanced selectivity for prostate cancer cells. In order to obtain PSA peptide substrates with improved specificity and plasma stability from the known substrate sequence glutaryl-Hyp-Ala-Ser-Chg-Gln, we systematically replaced the N-terminal segment with D-retro-inverso-peptides and incorporated &-amino-4-methylcoumarin (&-AMC) after Gln for convenient fluorometric determination and ranking of the PSA substrate activity. Based on PSA cleavage rate and resistance to hydrolysis in plasma, GABA←mGly-Ala-Ser-Chg-Gln and glutaryl-Ser-Ala-Ser-Chg-Gln were identified as optimal promoieties and coupled to doxorubicin or phosphoramide mustard as PSA-cleavable prodrugs, using various linkers. The doxorubicin conjugates demonstrated comparable PSA cleavage rates, equal or improved cytotoxic profiles in PSA-producing tumor cells compared to the prodrug L-3&&,202 (glutaryl-Ser-Ala-Ser-Chg-Gln-Ser-Leu-Dox). We found that human neprilysin rapidly cleaved L-3&&,202 through its Ser-Leu linker and may be responsible for prodrug instability in blood and normal tissues. Thus, in addition to enhancing prodrug selectivity against non-PSA-secreting prostate cancer cell lines, stability in normal tissues was improved. Our results indicated that enhanced tumor specificity of peptide prodrugs targeted for activation by PSA in prostate cancer tumors was achievable with peptide sequence and linker modifications.
Evidence for the influence of irrigation on precipitation intensity and totals in the midwestern United States
Creators: name: Alter, Ross Evan
Publisher: name: No Publisher Supplied
Year: 2014

description: Significant increases in summer precipitation occurred in the Midwestern United States over the last century for reasons that remain unclear.  It is postulated that the expansion of irrigation and cropland in the central US over the past sixty years has been a major contributor to these observed increases in precipitation.  As a first step toward attribution of these regional precipitation changes, a detailed analysis of observed daily summer precipitation frequency and intensity is conducted for the contiguous United States over multiple spatial scales and time periods from 1895 to 2011.  Robust increases in precipitation frequency, total precipitation, and moderate to heavy precipitation intensity are identified during July and August in the Midwestern US.  Analysis of changes in mean monthly precipitation from the early- to late-20th century initially points to increasing frequency as the source of increasing monthly precipitation in the Midwestern US during the summer, especially during August; however, comparable increases in precipitation frequency occur during other times of the year.  On the other hand, changes in precipitation intensity and total precipitation are both greatest during July and August and coincide spatially in the Midwestern US.  Additionally, the greatest intensity change occurs downwind of the most heavily irrigated regions, especially for the period between 1950 and 1980 when irrigation rapidly intensified.  A 15-day simulation using the WRF regional climate model with a simplified irrigation scheme over Nebraska confirmed the postulated increase in moisture, decrease in temperature, and subsequent increases in both convective inhibition and convective available potential energy over Nebraska, which led to weakened convection over the irrigated areas.  Wind anomalies produced by irrigation seem to be instrumental in enhancing precipitation intensity and totals downwind of Nebraska in general, and in the eastern Midwest region for one particular heavy precipitation event.  The increases in Midwestern precipitation in both analyses – one based on observation and rooted in reality and one based on model experiments and controlled for irrigation – support the hypothesis that irrigation in Nebraska has led to an increase in the intensity and total of precipitation downwind of the irrigated regions.
Novel drugs to inhibit breast cancer metastasis
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The change from a normal to a cancerous cell is accompanied by changes in the biological molecules at the surface of, and surrounding that cell. Some of these new biomolecules are unique enough to allow their use for diagnostic and treatment purposes. One protein component of the matrix of molecules that both surrounds a cell and forms the basement membrane is called laminin. Breast cancer cells attach to laminin using a specific laminin-binding protein (LBP), a cell surface protein. LBP expression provides an excellent prognostic indicator in breast cancer, and shows a positive correlation with progression in many solid tumors. This correlation likely results from the ability of LBP to enhance tumor cell attachment with the basement membrane as a prerequisite to spread in the body, or metastasis. Although laminin is a large protein, only a small part, called peptide 11, is involved in cell binding. When injected into test animals, peptide 11 can effectively block tumor spread to the lung and tumor angiogenesis (blood vessel growth). Unfortunately, other properties of peptide 11 make it unsuitable for immediate therapeutic applications. Thus, we have initiated a multi-disciplinary collaboration focused on structural analysis of peptide 11 to develop novel drugs for inhibition of breast cancer invasion and metastasis.

 Our project pursues a chemical approach to prepare, structurally analyze, and test laminin peptide 11-derived unusual amino acids and related analogs (peptidomimetics). The desired molecular properties include (i) increased hydrolytic stability, (ii) protein inhibition properties, and/or (iii) unique conformational restrictions. These properties are measured by both enhanced protein and cell binding and drug stability when administered by animal injection. Peptide 11 is very attractive as a lead, ‘parent’ compound for developing a novel therapeutic agent. We expect that molecules resembling peptide 11 will not have additional, unwanted biological effects. Thus, our research goal is to block movement of breast cancer cells to spread through the body. Our present inability to address tumor cell spread, or metastasis, is a challenge to develop novel drug treatments based on our current understanding of the molecular processes involved. Finally, our research has added potential application of being able to detect a protein (LBP) present on breast cancer cells, thus offering both a method of early detection and identifying those tumors with a dangerous metastatic potential.
Additional file 1: of Assessment of motivational interviewing: a qualitative study of response process validity, content validity and feasibility of the motivational interviewing target scheme (MITS) in general practice
Creators: name: RiĂŤtta Oberink
name: Boom, Saskia
name: Dijk, Nynke Van
name: Visser, Mechteld
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Semi-gestructureerde vragenlijst beoordeling MITS: This is the Dutch questionnaire that the assessors filled out when assessing the consultations. (DOCX 16Â kb)
Berthella martensi
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Pleurobranchomorpha
Pleurobranchidae
Berthella
Berthella martensi

description: Berthella martensi (Pilsbry, 1896)
(Figure 2 A)
Material examined. One specimen. MB28-004607, VIPP, 13 Dec. 2013, 9m, 14mm.
Habitats. Tropical coral reefs, under rubble coral.
Occurrences. Vamizi Island.
Geographic distribution. Indo-west, central Pacific and east Pacific. Pacific coast of Mexico, Hawaii, Taiwan, Solomon Islands, Papua New Guinea, Australia, Philippines, Indonesia, Thailand, Réunion Island, Mauritius, Tanzania (Gosliner et al. 2008), India (Sreeraj et al. 2012) and Mozambique.
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 9, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Genomics-aided insights into the Epichloë-turfgrass symbiosis
Creators: name: Ambrose Michael, Karen V.
Publisher: name: No Publisher Supplied
Year: 2014

description: Nearly all plants engage in some form of symbiosis with fungi. An association that is of broad significance in turf is the symbiosis between endophytic fungi of the genus Epichloë and cool season grasses. There has been longstanding interest in the relationship between turfgrass and their Epichloë endosymbionts as endophyte infection of turfgrass can result in increased plant vigor, and confer tolerance to biotic and abiotic stress. Thus the Epichloë-turfgrass interaction is a promising model for studies aimed at understanding beneficial symbiotic associations in general.    Fine fescues are valued as low maintenance turf spp. The E. festucae infection of strong creeping red fescue (Festuca rubra) is important because the symbiosis protects the host plant against fungal phytopathogens. The phytopathogens cause the devastating dollar spot, and red thread diseases. Remarkably, no other Epichloë-turfgrass interaction has been reported to confer fungal disease resistance. The E. festucae-infected fescues also have insect resistance.    No study to date has investigated the E. festucae-F. rubra mutualism. The goal of this thesis was to use SOLiD-SAGE transcriptome analysis to identify candidate genes that may be important in the endophyte-grass symbiosis.    The results of a high-throughput quantitative differential gene expression study between plants infected with E. festucae vis-à-vis endophyte-free plants, in addition to the discovery and functional characterization of a horizontally transferred gene into Epichloë spp., and the examination of E. festucae salicylate hydroxylase gene are detailed in this thesis. The findings from this dissertation are expected to contribute to the knowledge on fungal endosymbiont-plant mutualism.
Giudicato penale ed esecuzione delle sentenze della Corte europea dei diritti dell'uomo: profili processuali
Creators: name: Bigiarini, Andrea
Publisher: name: Universit� degli studi di Trento
Year: 2020

description: The present work aims to investigate the effects of the execution of the European Court of Human Rights? (ECtHR) judgments on the Italian criminal res judicata.
In the absence of a specific legislation, the research purpose is to face the numerous jurisprudential guidelines recently emerged on the above-mentioned topic by using a systematic approach, that can guide the study of a magmatic and evolving matter. The perspective adopted is a strict interpretation of the criminal res judicata institution, in response to the idea of a progressive erosion of its traditional features of stability and immutability.
Multiple lenses can be adopted to analyse the research theme: it can be studied both from the point of view of criminal law (substantive and procedural) and of constitutional law. The present work focuses on criminal procedure law aspects of the matter.
The goal of the first chapter - a sort of introduction - is twofold. On the one hand, the chapter is intended to present the domestic obligation to implement the ECtHR?s judgments in criminal cases. On the other, this chapter provides an analysis of the res judicata institution in the Italian procedural criminal law system.
The second and third chapters represent the core of this work. In order to comply with the above mentioned international obligation (both in the individual cases decided by the ECtHR and in the other cases similar to those already judged by the Court), the domestic judges in several cases have adopted procedural legal remedies, provided for other purposes by the Italian legislator. Such an analogical use of existing domestic remedies should be looked at critically.
Seeking to establish a comparison with the French and German legal systems, the last chapter depicts the pars costruens of the Doctoral Thesis.
Additional file 1: of Penicillin-G and oxytetracycline residues in beef sold for human consumption in Maroua, Cameroon
Creators: name: Ngom, Ronald Vougat
name: Garabed, Rebecca
name: Rumbeiha, Wilson
name: Harquin Foyet
name: Schrunk, Dwayne
name: Dahai Shao
name: AndrĂŠ Zoli Pagnah
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology

description: Materials and Method for the determination of Penicillin G and oxytetracycline residues. (DOCX 21Â kb)
Does Change in Emotional Expression Mediate Cancer Survival?
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: This proposal addresses the BCRP priority issues of prevention of breast cancer and prevention of disease progression. The overarching goal of this project is to determine the specific therapeutic component linking participation in supportive/expressive group therapy to observed differences in disease progression in women with metastatic breast cancer. Past research with supportive/expressive group therapy has shown that survival was extended in metastatic breast cancer patients by 18 months, doubling the survival time of a matched control group (Spiegel et al, 1989). It is vital that we begin to understand the possible therapeutic mechanisms and the underlying related physiological mechanisms responsible for this surprising finding of increased survival. Therefore, I propose to determine if change in emotional expression, amount of talk-time, or emotional control are therapeutic mechanisms related to survival, immune and endocrine function, and well-being in metastatic breast cancer patients who participate in a year of this group therapy.

 A long-standing hypothesis links both incidence and progression of cancer with lower levels of emotional expression, or higher levels of repressive or suppressive coping styles. This literature has guided the present hypothesis. In the proposed study, each participant has been videotaped as they take part in the supportive/expressive group therapy sessions. A sample of these videotapes will be used to code the specific emotions and the intensity of those emotions expressed for each of these women. The emotions expressed will be related to each woman's endocrine and immune functioning, her psychosocial well-being, and her survival. If it is found that change in emotional expression is important to enhanced physical or emotional well-being, this information could lead to more specific psychosocial interventions for breast cancer patients. The ability to provide such specific interventions would reduce the human and economic costs of breast cancer in California not only in terms of extended lives, but of quality of life.
Exploring job search outcomes for applicants with disabilities
Creators: name: Ameri, Mason
Publisher: name: No Publisher Supplied
Year: 2014

description: People with disabilities experience disparities in employment outcomes and studies point to employer discrimination as one likely cause. In this field experiment, fictional resumes and cover letters were sent to employers to assess the influence of disability on hiring decisions. Disability status was identified in the cover letters along with a sentence that briefly explained the mock applicant’s involvement in a disability organization. In addition, the applicants’ race was indicated through the use of common “White-sounding” and “Black-sounding” names. These resumes and cover letters were submitted to 6,016 job openings for accountant positions. The fictional resumes from people with disabilities were less likely to receive expressions of interest from employers, particularly if the resumes were from people with White-sounding names who had good experience. This study increases our understanding of the depth and nature of disability discrimination, as well as the ways disability may interact with other characteristics, such as applicants’ race and experience.
Erythrochiton rubronigrum Napp & Santos 1996
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Erythrochiton
Erythrochiton rubronigrum

description: 12. Erythrochiton rubronigrum Napp & Santos, 1996a: 238, fig. 1 Holotype, male
Type locality. Brazil, Espírito Santo: Baixo Guandú, 02-07.XI.1970, C. Elias
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 343, DOI: 10.5281/zenodo.250291
Berthellina delicata
Creators: name: Tibiriçá, Yara
name: Pola, Marta
name: Cervera, Juan Lucas
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Pleurobranchomorpha
Pleurobranchidae
Berthellina
Berthellina delicata

description: Berthellina delicata (Pease, 1861) species complex
(Figures 2 B–D)
Material examined. Twelve specimens. MB28-005057, ZWH, 5 Dec. 2011, 16m, 40mm; MB28-005058, ZRP, 0 7 Jun. 2012, 2m, 30mm; MB28-00 5059, ZRP, 0 7 Jun. 2012, 1m, 28mm; MB28-005060, ZRP, 0 7 Jun. 2012, 2m, 30mm; MB28-005061, ZRP, 26 May 2013, 1m, 30mm; MB28-005062, ZAR, 35m, 20mm; MHN-YT1013, VIS3, 12 Nov. 2013, 5m, 18mm; MB28-005063, VIS3, 12 Nov. 2013, 5m, 14mm; MB28-005 0 64, POA, 0 8 May 2014, 41m, 18mm; MB28-005065, NCh6, 0 5 Jun. 2014, 3m, 21mm; ZMBN105155, 21 May 2015, VIAIR, 2spcs., 4m, 12–26mm.
Habitats. Subtropical tidal reefs, rocky reefs and tropical coral reefs and bommies.
Occurrences. Ponta do Ouro, Zavora, Nuarro and Vamizi Island.
Geographic distribution. Indo-west, central Pacific. Hawaii, Midway Atoll (Gosliner et al. 2008), Japan (Baba 1949), Papua New Guinea, Seychelles, Réunion Island (Gosliner et al. 2008) and Mozambique (Martens 1879).
Remarks. Three-colour morphotypes were found: yellowish with a delicate reticulated pattern on the dorsum (Fig. 2 B); a translucent yellow body with low yellow tubercles (Fig. 2 C); and an orange body with white specks (Fig. 2 D). The variety of habitats, depths and specimen colours suggest that the animals collected here probably represent a complex of species. The systematics of Berthellina from the Indo-Pacific are in need of a comprehensive review (Cervera et al. 1999; Moustafa et al. 2016), because this taxon is indistinguishable by external characteristics alone (Gardiner 1936; Gosliner et al. 2008; Alvim & Pimenta 2015).
description: Published as part of Tibiriçá, Yara, Pola, Marta & Cervera, Juan Lucas, 2017, Astonishing diversity revealed: an annotated and illustrated inventory of Nudipleura (Gastropoda: Heterobranchia) from Mozambique, pp. 1-133 in Zootaxa 4359 (1) on page 10, DOI: 10.11646/zootaxa.4359.1.1, http://zenodo.org/record/1069168
Acoustic and elastic multiple scattering and radiation from cylindrical structures
Creators: name: Amirkulova, Feruza Abdukadirovna
Publisher: name: No Publisher Supplied
Year: 2014

description: Multiple scattering (MS) and radiation of waves by a system of scatterers is of great theoretical and practical importance and is required in a wide variety of physical contexts such as the implementation of ``invisibility" cloaks, the effective parameter characterization, and the fabrication of dynamically tunable structures, etc.  The dissertation develops fast, rapidly convergent iterative techniques to expedite the solution of MS problems. The formulation of MS problems reduces to a system of linear algebraic equations using  Graf's theorem and separation of variables. The iterative techniques  are developed  using Neumann expansion and Block Toeplitz structure of the linear system; they are very general,  and suitable  for parallel computations and  a large number of  MS problems, i.e.  acoustic, elastic, electromagnetic, etc., and used for the first time to solve MS problems.  The theory is implemented in Matlab and FORTRAN, and the theoretical predictions are compared to computations obtained by COMSOL.    To formulate the MS problem, the transition matrix is obtained by analyzing an acoustic and an elastic single scattering of incident waves by elastic isotropic and anisotropic solids. The mathematical model of wave scattering from multilayered cylindrical and spherical structures is developed  by means of an exact solution of dynamic 3D elasticity theory. The recursive impedance matrix  algorithm is derived for radially heterogeneous anisotropic solids.  An explicit method for finding the impedance in piecewise uniform, transverse-isotropic  material is proposed; the solution  is compared to elasticity theory solutions involving Buchwald potentials.    Furthermore, active exterior cloaking devices are modeled for acoustic and elastic media using multipole sources. A cloaking device can render an object invisible to some incident waves as seen by some external observer. The active cloak is generated by a discrete set of multipole sources that destructively interfere with an incident wave to produce zero total field over a finite spatial region.  The approach precisely determines the necessary source amplitudes and enables a cloaked region to be determined using Graf's theorem.  To apply the approach, the infinite series of multipole expansions are truncated, and the accuracy of cloaking is studied by modifying the truncation parameter.
Investigation of Improved Drug Delivery in Breast Cancer
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Improved delivery of diagnostic and therapeutic drugs to breast tumors is important for early detection and prevention of the progression of breast cancer. In this investigation, we will employ various vasoactive drugs to increase the preferential delivery of drugs to the tumors. If these drugs are used in conjunction with agents that are employed for imaging purposes they would increase the accuracy of the early detection of breast cancer. On the other hand, if they are used in combination with certain types of drugs for treatment they would deliver a larger proportion of their effect to the tumor while not damaging the surrounding normal tissues. The assessment of the accuracy of the new technique will be measured by dynamic magnetic resonance imaging (dMRI). The proposed investigation will specifically deal with the following BCRP priority areas: 1) pathogenesis of breast cancer (breast cancer biology), 2) prevention of disease progression by predicting the outcome of treatment, and finally 3) improvement of early detection of breast cancer by exploiting vascular properties of such tumors.

 In order to achieve the above goals, we will exploit the fact that tumor microvasculature is hyperpermeable (hyper-leaky) to large molecular weight imaging and therapeutic drugs as compared with normal blood vessels. We will also use our previous finding that MRI techniques combined with pharmacokinetic modeling can be used to measure the permeability in tumors as a function of spatial location. We will test the effect of drugs that alter the permeability of tumor vessels temporarily so that large molecular weight agents can be trapped in the extravascular space and spend a longer time in the tumor. The proposed studies will employ animal tumor models to understand the performance of the proposed approach in controllable tumor models so that the application of the technique can be extended to human breast cancer.

 Characterizing tumor permeability and other tumor transport parameters in breast cancer is important for the understanding of the pathogenesis of the disease, improved detection during the early stages due to the angiogenesis of neovasculature and corresponding vascular leakage, and in addition may aid in the prediction of bioavailability of chemotherapeutic agents to prevent the progression of disease. The successful outcome of the proposed research will positively impact all of the areas mentioned above.
Homogenes rubrogaster Napp & Santos 1996
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Homogenes
Homogenes rubrogaster

description: 13. Homogenes rubrogaster Napp & Santos, 1996b: 434, fig. 3 Holotype, male
Type locality. Brazil, Rondônia: Vilhena, 04.XI.1986, C. Elias.
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 343, DOI: 10.5281/zenodo.250291
Women’s rights foreign policy in the US congress
Creators: name: Angevine, Sara
Publisher: name: No Publisher Supplied
Year: 2014

description: In my dissertation, I analyze how and why US members of Congress represent the interests of women in foreign countries, what I call women’s rights foreign policy (WRFP). I explore what motivates US members of Congress, with limited time and resources, to legislate on behalf of foreign women and compare the differing WRFP objectives.  I apply a mixed-method approach from a feminist theoretical perspective. To assess the policy objectives, I conduct a content analysis of all WRFP bills introduced in the US House of Representatives between 1973-2010. To analyze congressional motivation, I construct a second dataset and gather relevant data on all members of Congress (US House) for three different Congresses (2005-10). Using regression analysis, I test which factors increase the probability of a member sponsoring a WRFP bill. To deepen my research findings, I conduct qualitative case studies of the three most widely supported WRFP bills introduced during the 111th Congress (2009-10): 1) a bill supporting the ratification of the Convention on the Elimination of All forms of Discrimination Against Women (CEDAW); 2) International Violence Against Women Act; and 3) International Protecting Girls from Child Marriage Act. In my research, I show the impact of domestic, foreign, and transnational interest groups on the US representation of global women's rights. I find that both traditional women’s rights policy entrepreneurs (women members of Congress) and traditional American foreign policy entrepreneurs (House Foreign Affairs Committee members) are motivated to sponsor WRFP legislation. The objectives of WRFP bills reflect these two divergent groups overlapping and competing policy interests. This unique coalition results in broader support for what I call “strategic feminist” goals and the persistent failure of “transnational feminist” goals. I also show the constraints of domestic gender politics. My research contributes to American politics, international relations, and women and politics research.
Nongenomic actions of antiestrogens
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: In many cases, breast cancers are stimulated to grow by estrogen, the female hormone. It is therefore beneficial to limit the amount of estrogen in contact with the tumor. One way to achieve this, without shutting down the body’s production of this essential hormone, is to block estrogen from interacting with the tumor. This can be accomplished with chemicals termed antiestrogens, such as tamoxifen. Tamoxifen’s molecular structure is similar to that of estrogen such that it binds to the estrogen receptor on the tumor, blocking the tumor from estrogen and not producing the stimulation of tumor growth that estrogen does.

 Whereas tamoxifen is taken by millions of cancer patients world-wide, and is presently being investigated as a preventive agent in 16,000 healthy women, its popularity does not come without concern. Recent research has indicated that the drug increases chances of developing uterine cancer. Although tamoxifen is a potent weapon when used early in cancer treatment, officials at the National Cancer Institute warn against prolonged use. This warning was further underscored by the State of California’s Proposition 65 to classify tamoxifen as an agent known to cause cancer.

 It is now thought that some actions of tamoxifen occur through mechanisms as yet unknown, other than through blockade of estrogen receptors. We have discovered that tamoxifen can interact with the surfaces of cells to send signals inside the cell. From our initial experiments, we believe that these cell surface signal properties are key both to some of the more recently-discovered benefits of tamoxifen, such as reversing drug-resistant cancers to drug-susceptible cancers and to some of the adverse effects. We intend to elucidate the mechanisms underlying some of the adverse and beneficial effects of tamoxifen and, with this knowledge, develop new drugs to bring to the clinic.
Diet & Breast Cancer in the California Teachers Study Cohort
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The specific relationships between a number of dietary factors and the development of breast cancer remain unclear. Clarification of these relationships is necessary to improve strategies for preventing the occurrence of this disease. The proposed research will evaluate several current and emerging hypotheses regarding nutrition and breast cancer risk in an established cohort of over 133,000 California teachers. The dietary components of interest include the role of plant estrogens, antioxidant vitamins, and the balance of dietary fat and fiber consumption.

 This study will provide us with a better understanding of the interrelationships between dietary components and breast cancer risk, that is, information that will help guide strategies for breast cancer prevention. Using a recently developed unique database containing the content of seven different estrogen compounds in a wide variety of foods, this research project will be the first-ever prospective study to examine in a detailed manner the relationship between plant estrogens and breast cancer risk. In addition, the size of this study allows us to look at the joint role that other compounds found in fruits and vegetables (including antioxidant vitamins and fiber) play in what was recently described by an international expert review committee as the "probable" protective effect of fruits and vegetables on breast cancer risk. Finally, investigation of the balance of fat and fiber in the diet will provide insight into the controversy regarding the role of dietary fat in the development of breast cancer and thus, improve approaches to dietary prevention.

 The California Teachers Study (CTS) cohort was established by investigators interested in environmental, genetic, and nutritional epidemiology, hormonal carcinogenesis, and public health. Participants in the CTS cohort were previously asked about their dietary intake and a wide variety of other lifestyle factors. Each year, approximately 480 members of the cohort will develop breast cancer. We will evaluate our hypotheses by comparing the dietary intake of those who development breast cancer during the next two years to those who don't, taking into account other lifestyle factors.

 This project will provide important information on the recent effects of diet on the development of breast cancer and thus, on potentially promising avenues for breast cancer prevention through dietary modification in adult women. This is particularly important for California teachers who, for unknown reasons, have a higher than expected risk of breast cancer. In addition, the findings should add substantially to public health recommendations regarding dietary modification that are likely to be forthcoming in the next several years.
Mallosoma piptadeniae Giacomel 1976
Creators: name: Monné, Miguel A.
name: Almeida, Lucia M.
name: Oliveira, Marcio L.
name: Viana, Jéssica Herzog
name: Monné, Marcela L.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Mallosoma
Mallosoma piptadeniae

description: 14. Mallosoma piptadeniae Giacomel, 1976: 2, figs. 1 – 25 (Figure 4) Holotype, male
Type locality. Brazil, Paraná: Jaguariaiva, 06.VIII.1972, Fioravante Giacomel.
description: Published as part of Monné, Miguel A., Almeida, Lucia M., Oliveira, Marcio L., Viana, Jéssica Herzog & Monné, Marcela L., 2017, Checklist of Cerambycidae (Coleoptera) primary types of the Coleção Entomológica Pe. Jesus Santiago Moure, Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil, Instituto Nacional de Pesquisas da Amazônia, Amazonas, Manaus, Brazil, and of the Museu Paraense, pp. 341-365 in Zootaxa 4221 (3) on page 343, DOI: 10.5281/zenodo.250291