Additional file 1 of The epidemiologic impact and cost-effectiveness of new tuberculosis vaccines on multidrug-resistant tuberculosis in India and China
Creators: name: Weerasuriya, Chathika K
name: Harris, Rebecca C
name: McQuaid, C Finn
name: Bozzani, Fiammetta
name: Ruan, Yunzhou
name: Li, Renzhong
name: Li, Tao
name: Rade, Kirankumar
name: Rao, Raghuram
name: Ginsberg, Ann M
name: Gomez, Gabriela B
name: White, Richard G
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Additional file 1: Technical Appendix. Figure S1 Model diagram. S2 Case Detection and Treatment Success Rates. S3 Demographic Model–India and China. S4 Posterior distributions of sampled parameters—India. S5 Posterior distributions of sampled parameters—India (contd). S6 Posterior distributions of sampled parameters—China. S7 Posterior distributions of sampled parameters—China (contd). S8 Calibration Results—All Tuberculosis in India. S9 Calibration Results—RR/MDR-TB in India. S10 Baseline (no vaccine) projections–India. S11 Calibration Results—Prevalence and Incidence of All TB in China. S12 Calibration Results—Notifications and Mortality of All TB in China. S13 Calibration Results—RR/MDR-TB in China. S14 Baseline (no vaccine) projections–China. S15 Latent tuberculosis infection. S16 Incident tuberculosis, disaggregated by incidence source. S17 Incidence Rate Reduction in India. S18 Mortality Rate Reduction in India. S19 Incidence Rate Reduction in China. S20 Mortality Rate Reduction in China. S21 RR/MDR-TB Cases Averted in India by 2030 and 2050. S22 RR/MDR-TB Deaths Averted in India by 2030 and 2050. S23 All TB Cases Averted in India by 2030 and 2050. S24 All TB Deaths Averted in India by 2030 and 2050. S25 RR/MDR-TB Cases Averted in China by 2030 and 2050. S26 RR/MDR-TB Deaths Averted in China by 2030 and 2050. S27 All TB Cases Averted in China by 2030 and 2050, S28 All TB Deaths Averted in China by 2030 and 2050. S29 RR/MDR-TB Treatment Regimens Averted by 2030 &amp; 2050 in India. S30 DS-TB Treatment Regimens Averted by 2030 &amp; 2050 in India. S31 RR/MDR-TB Treatment Regimens Averted by 2030 &amp; 2050 in China. S32 DS-TB Treatment Regimens Averted by 2030 &amp; 2050 in China. S33 ICER for vaccination in India at USD 10 per vaccine. S34 ICER for vaccination in India at USD 30 per vaccine. S35 ICER for vaccination in China at USD 10 per vaccine. S36 ICER for vaccination in China at USD 30 per vaccine. S37 ICER for vaccination in China at USD 10 per vaccine. S38 ICER for vaccination in China at USD 30 per vaccine. S39 ICER for vaccination in India at USD 10 per vaccine and 30% mass campaign coverage. S40 ICER for vaccination in China at USD 10 per vaccine and 30% mass campaign coverage. Tables S1 Model equations—symbols. S2 Parameters for births and deaths. S3 Parameters determining transmission and drug-resistance. S4 Parameters determining disease progression. S5 Parameters determining disease relapse and natural cure. S6 Parameters related to treatment initiation and treatment success. S7 Scale up of drug sensitivity testing coverage in the “Policy” scenario in China. S8 RR/MDR-TB treatment regimens in the China “Policy” scenario. S9 Calibration targets—India Rates are expressed per 100,000 population. S10 Calibration targets—China. S11 China Incidence Target Data. S12 Modelled vaccine types and impact on disease states. S13 TB-related Unit Costs. S14 Vaccine-related Costs. S15 Willingness to Pay Thresholds. S16 Vaccine Impact by 50% efficacy, 10-year P&amp;PI and PSI vaccines. S17 Incidence of TB disaggregated by origin.