cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Corpus alienum.
Creators: name: Constantine, Sarah
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Emergency
subject: Conventional radiography
subject: CT
subject: Ultrasound
subject: Catheters
subject: Complications
subject: Foreign bodies

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: To recognize the radiological appearances of various foreign bodies. To be aware of the complications of foreign bodies, especially if not recognized and treated...
MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation
Creators: name: Wang, Hengbin
name: Pledger, Jack W.
name: Yang, Yonghua
name: Ramamoorthy, Sivapriya
name: Zhang, Xiaohong
name: Ma, Qiuping
name: Nawaz, Zafar
name: Shimojima, Tsukasa
name: Chen, Lei
name: Zhang, Mu
name: Li, Pengfei
name: Nicosia, Santo V.
name: Zhang, Yanping
name: Fu, Wei
name: Bai, Wenlong
name: Shen, Zheng
name: Zhang, Yingtao
name: Chen, Jiandong
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Members of the FOXO (forkhead O) class of transcription factors are tumor suppressors that also control aging and organismal life span. Mammalian FOXO degradation is proteasome-mediated, although the ubiquitin E3 ligase for FOXO factors remains to be defined. We show that MDM2 binds to FOXO1 and FOXO3A and promotes their ubiquitination and degradation, a process apparently dependent on FOXO phosphorylation at AKT sites and the E3 ligase activity of MDM2. Binding of MDM2 to FOXO occurs through the region of MDM2 that directs its cellular trafficking and the forkhead box of FOXO1. MDM2 promotes the ubiquitination of FOXO1 in a cell-free system, and its knockdown by small interfering RNA causes accumulation of endogenous FOXO3A protein in cells and enhances the expression of FOXO target genes. In cells stably expressing a temperature-sensitive p53 mutant, activation of p53 by shifting to permissive temperatures leads to MDM2 induction and degradation of endogenous FOXO3A. These data suggest that MDM2 acts as an ubiquitin E3 ligase, downstream of p53, to regulate the degradation of mammalian FOXO factors.
title: Assessment of urinary tract obstruction as a cause of acute renal failure with CTKUB
Creators: name: Zang, Johnson Jun-liang
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Kidney
subject: Urinary Tract / Bladder
subject: Abdomen
subject: CT
subject: Outcomes analysis
subject: Calcifications / Calculi
subject: Obstruction / Occlusion

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: To assess the necessity of CTKUB imaging (Computed Tomography of Kidney, Ureters and Bladder) to investigate for post-renal obstruction for patients presenting with acute renal failure only; to compare the likelihood post-renal obstructions as a...
Occurrence of a blind Lophius budegassa in the Mediterranean Sea
Creators: name: COLMENERO, Ana I.
name: DEMESTRE, Montserrat
name: SÁNCHEZ, Pilar
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: The first specimen of a blind Lophius budegassa found in the Mediterranean Sea was caught during the scientific survey "COMSOM" conducted in June 2009 in the fishing grounds off Cap de Creus (NW Mediterranean Sea) with an experimental beam trawl at 90 m depth. The individual is described, and biometric measurements and meristic data provided. The presence of the microsporidian parasite Spraguea lophii was also observed.
title: Eine diskurslinguistische Untersuchung zur Kommunikation von Hochhäusern in Wien
Creators: name: Plakolm, Marie Sophie
Year: 2023

description: In den letzten Jahren wurden in Wien zahlreiche Hochhäuser errichtet, deren Vermarktung über durchdesignte Werbeauftritte erfolgt. Dieser Entwicklung zum Anlass beschäftigt sich die vorliegende Masterarbeit mit der textuellen und visuellen Kommunikation von Hochhäusern in Wien. Ziel ist es, diskursive Muster auf der lexikalischen, visuellen, metaphorischen und argumentativen Ebene aufzudecken, wenn über Hochhäuser in Wien kommuniziert wird. Das multimediale Korpus umfasst Texte und Bilder aus Zeitungen (Der Standard, Die Presse, Falter, Kronen Zeitung, Kurier, Wiener Zeitung), der Werbung (Homepages der Immobilienprojekte TrIIIple, Marina Tower und Danubeflats) und mit dem Hochhauskonzept 2014 einen Text aus der Politik und Verwaltung. Die Analyse der Lexik zeigt, dass für den Sachverhalt Hochhaus in vielen Fällen Nominationen verwendet werden (Turm, Tower, Wolkenkratzer, vertikale Stadt). Auf der visuellen Ebene lassen sich die Bilder fünf Arten von Schlagbildern zuordnen, die allesamt zur Kategorie der Fahnenbilder zählen. Bei den Metaphern treten drei dominante Konzepte (Organismus-Metaphorik, Wirtschafts- und Produktionsmetaphorik, Orientierungsmetaphorik) hervor, anhand derer sich die herausgearbeiteten Bereiche strukturieren. Die Analyse der Argumentationen offenbart sechs zentrale Topoi (Zukunfts-Topos, Nutzen-Topos, Macht-Topos, Ökonomie-Topos, Weltstadt-Topos, Wohnraum-Topos), die herangezogen werden, um die eigene Perspektive durchzusetzen. Darüber hinaus wird deutlich, dass über die Art und Weise, wie die Hochhäuser textuell und visuell vermarktet werden, gewisse Images von Wohnen erzeugt werden, welche, so die Hoffnung der Käufer*innen, mit dem Erwerb der Immobilie auf die eigene Person übergehen.
Further range expansion of the blue crab Callinectes sapidus (Rathbun, 1896) (Crustacea: Decapoda: Brachyura) in Turkish waters, Northern Aegean Sea: insight into distribution depth
Creators: name: DABAN, İsmail Burak
name: CENGİZ, Özgür
name: TUNÇER, Sezginer
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: A new record of Callinectes sapidus from the northern eastern part of the Aegean Sea is presented, based on a live single female sampled off northern part of the Gökçeada (Imbroz) Island. Surprisingly, the individual which is known shelf-estuarine species was sampled at 220 m depth with a bottom trawl on November 15th, 2015.
(4030) Bridget McKenna
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
LES ASCIDIES DES GRANDES PROFONDEURS RÉCOLTÉES PAR LES NAVIRES ATLANTIS II ET CHAIN. 3e NOTE
Creators: name: MONNIOT, Françoise
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1971

description: This new collection derived from a deep sea zone off the atlantic coasts of United States and the equatorial atlantic ocean contains 16 species,5ofwhich are new. The size of the animals is extremely reduced: some adult individuals measure less than 1 mm in diameter. Some original forms; Protomolgula and Bathypyura exhibit an extremely simplified morphology with numerous juvenile characteristics.
Mechanical Loading Regulates NFATc1 and β-Catenin Signaling through a GSK3β Control Node
Creators: name: Case, Natasha
name: Styner, Maya
name: Rubin, Clinton T.
name: Xie, Zhihui
name: Sen, Buer
name: Rubin, Janet
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Mechanical stimulation can prevent adipogenic and improve osteogenic lineage allocation of mesenchymal stem cells (MSC), an effect associated with the preservation of β-catenin levels. We asked whether mechanical up-regulation of β-catenin was critical to reduction in adipogenesis as well as other mechanical events inducing alternate MSC lineage selection. In MSC cultured under strong adipogenic conditions, mechanical load (3600 cycles/day, 2% strain) inactivated GSK3β in a Wnt-independent fashion. Small interfering RNA targeting GSK3β prevented both strain-induced induction of β-catenin and an increase in COX2, a factor associated with increased osteoprogenitor phenotype. Small interfering RNA knockdown of β-catenin blocked mechanical reduction of peroxisome proliferator-activated receptor γ and adiponectin, implicating β-catenin in strain inhibition of adipogenesis. In contrast, the effect of both mechanical and pharmacologic inhibition of GSK3β on the putative β-catenin target, COX2, was unaffected by β-catenin knockdown. GSK3β inhibition caused accumulation of nuclear NFATc1; mechanical strain increased nuclear NFATc1, independent of β-catenin. NFATc1 knockdown prevented mechanical stimulation of COX2, implicating NFATc1 signaling. Finally, inhibition of GSK3β caused association of RNA polymerase II with the COX2 gene, suggesting transcription initiation. These results demonstrate that mechanical inhibition of GSK3β induces activation of both β-catenin and NFATc1 signaling, limiting adipogenesis via the former and promoting osteoblastic differentiation via NFATc1/COX2. Our novel findings suggest that mechanical loading regulates mesenchymal stem cell differentiation through inhibition of GSK3β, which in turn regulates multiple downstream effectors.
(4031) William Peter Kean
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 1 of Higher amoebic and metronidazole resistant forms of Blastocystis sp. seen in schizophrenic patients
Creators: name: Franklin, Freddy
name: Rajamanikam, Arutchelvan
name: Raju, Chandramathi Samudi
name: Gill, Jesjeet Singh
name: Francis, Benedict
name: Sy-Cherng, Luke Woon
name: Kumar, Suresh
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Table S1. Prevalence of Blastocystis sp. in SZ and NS group.
Modeling vertical structure in circular velocity of spiral galaxy NGC 4244
Creators: name: Jałocha, Joanna
name: Bratek, Łukasz
name: Sikora, Szymon
name: Kutschera, Marek
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We study the vertical gradient in azimuthal velocity of spiral galaxy NGC 4244 in a thin disk model. With surface density accounting for the rotation curve, we model the gradient properties in the approximation of quasi-circular orbits and find the predictions to be consistent with the gradient properties inferred from measurements. This consistency may suggest that the mass distribution in this galaxy is flattened.
description: 5 pages, 6 figures
title: Feasible Reduction of Female Breast Dose in Routine Chest CT: From Filtered Back Projection to Iterative Reconstruction
Creators: name: Kapur, Subhash
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Breast
subject: CT
subject: Dosimetry
subject: Dosimetric comparison

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Optimization of CT dose to the chest is important as radiosensitive organs breast, lungs and thyroid are exposed to radiation during scanning. We have compared radiation dose metrics and image quality in two CT scanners both using tube current...
title: The Rise, Consolidation and Disintegration of Dlamini Power in Swaziland Between 1820 and 1889. A Study in the Relationship of Foreign Affairs to Internal Political Development.
Creators: name: Bonner, Philip Lewis
Publisher: name: School of Oriental and African Studies, University of London
Year: 1977

description: The Swazi kingdom grew out of the pressures associated with competition for trade and for the rich resources of Shiselweni. While centred on this area it acquired some of its characteristic features - notably a regimental system, and the dominance of a Dlamini aristocracy. Around 1815 the Swazi came under pressure from the South, and were forced to colonise the land lying north of the Lusutfu. Here they remained for some years a nation under arms, as they plundered local peoples, and were themselves swept about by the currents of the Mfecane. In time a more settled administration emerged, as the aristocracy spread out from the royal centres at Ezulwini, and this process accelerated under Mswati as he subdued recalcitrant chiefdoms, and restructured the regiments. Consequently, by the time Mswati died in 1865, Dlamini power was sufficiently entrenched for there to be no serious disturbance, and for a regency to function smoothly for the following decade. Externally the dominant influence was the Zulu, who continually threatened the kingdom's stability. The Swazi were forced by these attacks to look for allies in the Boers, and to make several territorial cessions from 1846. Nevertheless, the relations they established were not markedly unequal, since the Republic were dependent on the Swazi in various ways. Consequently, the Swazi were able to take charge of the lowveld in the north, and by the 1860s reached the pinnacle of their power. The consolidation of the South African Republic following the British annexation, and the discovery of gold, meant that this freedom was gradually lost, and in the 1880s pressure mounted on Swaziland itself. The clearest index of this lies in the country's conquest by concessions, which eventually so eroded the social fabric of the country that a pretext was given for the Republic and Britain to intervene.
Melanoma Antigen Gene Protein-A11 (MAGE-11) F-box Links the Androgen Receptor NH 2 -terminal Transactivation Domain to p160 Coactivators
Creators: name: Minges, John T.
name: Bai, Suxia
name: Wilson, Elizabeth M.
name: Hnat, Andrew T.
name: Askew, Emily B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Androgen-dependent transcriptional activity by the androgen receptor (AR) and its coregulators is required for male reproductive development and function. In humans and other primates, melanoma antigen gene protein-A11 (MAGE-11) is an AR selective coregulator that increases AR transcriptional activity. Here we show that the interaction between AR and MAGE-11 is mediated by AR NH2-terminal FXXLF motif binding to a highly conserved MAGE-11 F-box in the MAGE homology domain, and is modulated by serum stimulation of mitogen-activated protein kinase phosphorylation of MAGE-11 Ser-174. The MAGE-11-dependent increase in AR transcriptional activity is mediated by a direct interaction between MAGE-11 and transcriptional intermediary factor 2 (TIF2) through the NH2-terminal region of TIF2, and by a MAGE-11 FXXIF motif interaction with an F-box-like region in activation domain 1 of TIF2. The results suggest that MAGE-11 functions as a bridging factor to recruit AR coactivators through a novel FXX(L/I)F motif-F-box interaction paradigm.
A new deep-sea lobster of the genus Thymopides (Crustacea: Decapoda: Nephropidae) collected near the hydrothermal vent Snake Pit, Mid-Atlantic Ridge
Creators: name: SEGONZAC, Michel
name: MACPHERSON, Enrique
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2003

description: A second species of the genus Thymopides, T. laurentae sp. nov., is described from a specimen trapped at 3505 m
 depth in the Mid-Atlantic Ridge, near the Snake Pit hydrothermal area. This new species is easily distinguishable from the
 type species T. grobovi, collected off the subantarctic islands Heard and Kerguelen, at depth between 525 and 1220 m, by
 its smooth carapace, the abdomen without longitudinal median carina and the palm of the first pereopod distinctly longer
 than wide.
Observation of molecular dipole excitations by attosecond self-streaking
Creators: name: Wachter, Georg
name: Nagele, Stefan
name: Sato, Shunsuke A.
name: Pazourek, Renate
name: Wais, Michael
name: Lemell, Christoph
name: Tong, Xiao-Min
name: Yabana, Kazuhiro
name: Burgdörfer, Joachim
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: Atomic and Molecular Clusters (physics.atm-clus)
subject: FOS: Physical sciences

description: We propose a protocol to probe the ultrafast evolution and dephasing of coherent electronic excitation in molecules in the time domain by the intrinsic streaking field generated by the molecule itself. Coherent electronic motion in the endohedral fullerene \Necsixty~is initiated by a moderately intense femtosecond UV-VIS pulse leading to coherent oscillations of the molecular dipole moment that persist after the end of the laser pulse. The resulting time-dependent molecular near-field is probed through the momentum modulation of photoemission from the central neon atom by a time-delayed attosecond XUV pulse. Our ab-initio time-dependent density functional theory and classical trajectory simulations predict that this self-streaking signal accurately traces the molecular dipole oscillations in real time. We discuss the underlying processes and give an analytical model that captures the essence of our ab-initio simulations.
Additional file 2 of Higher amoebic and metronidazole resistant forms of Blastocystis sp. seen in schizophrenic patients
Creators: name: Franklin, Freddy
name: Rajamanikam, Arutchelvan
name: Raju, Chandramathi Samudi
name: Gill, Jesjeet Singh
name: Francis, Benedict
name: Sy-Cherng, Luke Woon
name: Kumar, Suresh
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2: Table S2. Generation time, number of generations, and size of Blastocystis sp. isolated from schizophrenic patients (SZ1-SZ9) and non-schizophrenic individuals (NS1-NS5).
Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes: A POSSIBLE ROLE IN AMYOTROPHIC LATERAL SCLEROSIS
Creators: name: Caplow, Michael
name: Yu, Yanbao
name: Zhou, Li
name: Jordon, Joshua K.
name: Dokholyan, Nikolay V.
name: Wilcox, Kyle C.
name: Redler, Rachel L.
name: Huang, Yi
name: Chen, Xian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Over 100 mutations in Cu/Zn-superoxide dismutase (SOD1) result in familial amyotrophic lateral sclerosis. Dimer dissociation is the first step in SOD1 aggregation, and studies suggest nearly every amino acid residue in SOD1 is dynamically connected to the dimer interface. Post-translational modifications of SOD1 residues might be expected to have similar effects to mutations, but few modifications have been identified. Here we show, using SOD1 isolated from human erythrocytes, that human SOD1 is phosphorylated at threonine 2 and glutathionylated at cysteine 111. A second SOD1 phosphorylation was observed and mapped to either Thr-58 or Ser-59. Cysteine 111 glutathionylation promotes SOD1 monomer formation, a necessary initiating step in SOD1 aggregation, by causing a 2-fold increase in the Kd. This change in the dimer stability is expected to result in a 67% increase in monomer concentration, 315 nm rather than 212 nm at physiological SOD1 concentrations. Because protein glutathionylation is associated with redox regulation, our finding that glutathionylation promotes SOD1 monomer formation supports a model in which increased oxidative stress promotes SOD1 aggregation.
Ascidies coloniales de la ride médio-atlantique récoltées à proximité de sites hydrothermaux
Creators: name: MONNIOT, Françoise
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2003

description: Colonial ascidians from  the Mid-Atlantic Ridge near hydrothermal sites. Two colonial ascidians species, one of
 which is new, were collected during the Portuguese cruise "SEAHMA 1" near a hydrothermal site, west of  the Azores
 islands. These particularly brittle organisms, never collected undamaged by dredges or trawls, were captured in good
 conditions by the submersible ROV Victor 6000 aboard the N.O. L'Atalante. This now allows precise descriptions.
Energy shift due to anisotropic black body radiation
Creators: name: Flambaum, Victor V.
name: Porsev, Sergey G.
name: Safronova, Marianna S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: In many applications a source of the black-body radiation (BBR) can be highly anisotropic. This leads to the BBR shift that depends on tensor polarizability and on the projection of the total angular momentum of ions and atoms in a trap. We derived formula for the anisotropic BBR shift and performed numerical calculations of this effect for Ca$^+$ and Yb$^+$ transitions of experimental interest. These ions used for a design of high-precision atomic clocks, fundamental physics tests such as search for the Lorentz invariance violation and space-time variation of the fundamental constants, and quantum information. Anisotropic BBR shift may be one of the major systematic effect in these experiments.
description: 1) A consideration of the case when a certain portion of photons is emitted to the solid angle Omega1 at the temperature T1 and another portion of photons is emitted to the solid angle Omega2 at the temperature T2 is added. 2) The journal reference is added. 6 pages, 1 figure
(4027) Cleonice Stuart Wallace
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Integrali di Cauchy ed esercizi vari
Creators: name: Sparavigna, Amelia Carolina
Publisher: name: Zenodo
Year: 2020
Subjects: Matematica per la Fisica

description: L'Analisi Complessa è la parte dell'analisi che studia le funzioni di variabile complessa. Essa è utilizzata in matematica, fisica e ingegneria e, più di recente, nella teoria quantistica dei campi. Le radici di tale analisi stanno nei lavori di Eulero, Gauss, Riemann, Cauchy, Weierstrass, e poi di molti altri ricercatori del XX secolo. In questo scritto ci occuperemo in particolare degli integrali di Cauchy e dei calcoli che sono ad essi legati. Si discuteranno alcuni problemi di fisica che usano tale tecnica d'integrazione. Vari esercizi di calcolo saranno proposti.
title: Datengetriebene Energiestrategie
title: Aufbau und Nutzen einer zentralen Cloud BI-Lösung
titleType: Subtitle
Creators: name: Meditz, Patrick
Publisher: name: FH CAMPUS 02 (CAMPUS 02 Fachhochschule der Wirtschaft)
Year: 2025
Subjects: subject: 658 Allgemeines Management

description: Diese Masterarbeit untersucht den Einsatz von Business Intelligence (BI) im Energiesektor, wobei der Fokus auf dem aktuellen Stand, den potenziellen Vorteilen und den Herausforderungen in diesem spezifischen Bereich liegt. Ein wichtiger Aspekt der Arbeit ist die detaillierte Betrachtung einer Fallstudie zur Implementierung einer zentralen Cloud-BI-Plattform in einem Energieversorgungsunternehmen. Diese Fallstudie bietet konkrete Einblicke in die Herausforderungen und Chancen, die mit der Einführung einer solchen Plattform verbunden sind. Basierend auf den Erkenntnissen aus dem theoretischen Teil und der Fallstudie wird eine Umfrage durchgeführt, um einerseits den Nutzen und die Herausforderungen von BI in der Energiewirtschaft zu identifizieren und andererseits die Wahrnehmung hinsichtlich der implementierten BI-Plattform aufzuzeigen. Diese Umfrage zielt darauf ab, eine ganzheitliche Perspektive auf den Einsatz von BI im Energiesektor zu gewinnen und Möglichkeiten zur Optimierung der BI-Strategien in Unternehmen dieses Bereichs aufzuzeigen.
description: This master's thesis investigates the application of Business Intelligence (BI) in the energy sector, with a focus on the current state, potential benefits, and challenges specific to this domain. An important aspect of the study involves a detailed examination of a case study regarding the implementation of a central Cloud BI platform within an energy supply company. This case study provides tangible insights into the challenges and opportunities associated with introducing such a platform. Drawing upon insights gained from both the theoretical framework and the case study, a survey is conducted to explore the benefits and challenges of BI in the energy industry and to gauge perceptions regarding the implemented BI platform. This survey aims to attain a holistic understanding of BI utilization in the energy sector and to highlight opportunities for optimizing BI strategies within companies operating in this domain.
Modulation of the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances Tumor Cell Invasion and Proliferation in Three-dimensional Collagen Matrices
Creators: name: Munshi, H. G.
name: Liu, Yueying
name: Moss, Natalie M.
name: Wu, Yi I.
name: Stack, M. Sharon
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Increasing evidence suggests that the cytoplasmic tail of membrane type 1 matrix metalloproteinase (MT1-MMP) is subject to phos pho ryl a tion and that this modification may influence its enzymatic activity at the cell surface. In this study, phos pho ryl a ted MT1-MMP is detected using a phospho-specific antibody recognizing a protein kinase C consensus sequence (phospho-TXR), and a MT1-MMP tail peptide is phos pho ryl a ted by exogenous protein kinase C. To characterize the potential role of cytoplasmic residue Thr567 in these processes, mutants that mimic a state of either constitutive (T567E) or defective phos pho ryl a tion (T567A) were expressed and analyzed for their functional effects on MT1-MMP activity and cellular behavior. Phospho-mimetic mutants of Thr567 exhibit enhanced matrix invasion as well as more extensive growth within a three-dimensional type I collagen matrix. Together, these findings suggest that MT1-MMP surface action is regulated by phos pho ryl a tion at cytoplasmic tail residue Thr567 and that this modification plays a critical role in processes that are linked to tumor progression.
ÉTUDE COMPARATIVE DES ACTIVITÉS PHOSPHOMONOESTÉRASIQUES ALCALINES DU TUBE DIGESTIF DE PLUSIEURS ESPÈCES D'ASTÉROIDES (ÉCHINODERMES) précédée d'une NOTE ANATOMIQUE
Creators: name: JANGOUX, Michel
name: VAN-IMPE, Edwin
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 1971

description: The study of the comparative anatomy of the experimented asteroids’ digestive tract puts the accent on the great morphologic variation of the digestive tract according to the considered species. The relations between pyloric stomach and pyloric canals are subjected to important modifications, as the size of the cardiac stomach.Theauthorsdescribea «superior stomacal complex», very special organ observed in three starfish species supposed microphagous.
The alkaline phosphatase has been titrated in all the digestive organs. The pyloric caeca show a rather strong activity, but the activity is most important at the level of « superior stomacal complex ». The Tiedemann pouches present verylittlealkalinephosphatase.
(4029) Robert Kean
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Synchrotron Origin of the Typical GRB Band Function - A Case Study of GRB 130606B
Creators: name: Zhang, Bin-Bin
name: Uhm, Z. Lucas
name: Connaughton, Valerie
name: Briggs, Michael S.
name: Zhang, Bing
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We perform a time-resolved spectral analysis of GRB 130606B within the framework of a fast-cooling synchrotron radiation model with magnetic field strength in the emission region decaying with time, as proposed by Uhm & Zhang. The data from all time intervals can be successfully fit by the model. The same data can be equally well fit by the empirical Band function with typical parameter values. Our results, which involve only minimal physical assumptions, offer one natural solution to the origin of the observed GRB spectra and imply that, at least some, if not all, Band-like GRB spectra with typical Band parameter values can indeed be explained by synchrotron radiation.
description: 9 pages, 7 figures, 1 table
Fishery biology of Sepia orbignyana (Férussac in d'Orbigny, 1826) (Cephalopoda: Sepiidae) from Algerian coast (Southwestern Mediterranean Sea)
Creators: name: GUEDIOURA, Abdelmoumène
name: BOUKROUFA, Fayçal
name: REBZANI-ZAHAF, Chafika
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: The reproductive aspects of Sepia orbignyana were studied on 890 individuals between January 2013 and January 2014 on the central Algerian coast (Cap Chenoua to Cap Djinet). Distribution length frequency analysis showed that mantle lengths varied between 30 and 83 mm in males and 35 and 96 mm in females. The observed maximum length was 95.5 mm and 82.6 mm for females and males, respectively. The sex ratio for the entire sample was 1.65:1 and showed a significant predominance of females over males during all the seasons at the exception of autumn. According to the length, females were more dominant (63.26%) for lengths comprised between 55 and 85 mm, while the distribution was homogenous for the lengths class under 55 mm and between 60 and 65 mm. Length-weight relationship examined for each sex and the total sample exhibited negative allometric growth while in winter male growth was isometric. For both sexes, the allometric coefficient in immature, maturing and mature individuals indicated negative growth. The length at 50% maturity has shown that males matured earlier in comparison to females. Monthly monitoring of maturity indexes showed several periods of breeding with an important period occurring between spring and summer. Overall, we report that Sepia orbignyana would likely behave as an intermittent spawner on the Algerian coast similarly to Sepietta oweniana, a cephalopod sepiolid.
title: A novel approach for imaging branchial anomalies – Percutaneous dilute gadolinium contrast injection prior to MRI
Creators: name: Khanna, Anmol
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Head and neck
subject: Ear / Nose / Throat
subject: Contrast agents
subject: MR
subject: Contrast agent-other
subject: Experimental investigations
subject: Fistula
subject: Education and training

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Branchial apparatus consists of 5 meso-dermal arches separated by invaginations of the ectoderm called as clefts. Although branchial anomalies are relatively uncommon, they are the second most common head and neck congenital lesions in children....
title: Imaging some of the less common causes of spinal stenosis
Creators: name: See, Poh Lye Paul
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Diagnostic procedure
subject: MR
subject: CT
subject: Neuroradiology spine
subject: Musculoskeletal system
subject: Musculoskeletal soft tissue
subject: Education and training

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: A review of some of the less common causes of spinal canal stenosis including examples and their imaging...
Additional file 4 of Higher amoebic and metronidazole resistant forms of Blastocystis sp. seen in schizophrenic patients
Creators: name: Franklin, Freddy
name: Rajamanikam, Arutchelvan
name: Raju, Chandramathi Samudi
name: Gill, Jesjeet Singh
name: Francis, Benedict
name: Sy-Cherng, Luke Woon
name: Kumar, Suresh
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 4: Table S3. Intensity of fluorescence and percentage of fluorescent forms of Blastocystis sp. labelled with FITC-labelled lectins.
MTA1 Coregulator Regulates p53 Stability and Function
Creators: name: Rayala, Suresh K.
name: Wu, Xifeng
name: Li, Da Qiang
name: Pakala, Suresh B.
name: Kumar, Rakesh
name: Reddy, Sirigiri Divijendra Natha
name: Zhang, Yanping
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Although metastasis-associated protein 1 (MTA1) has recently been shown as a DNA damage responsive protein, the underlying mechanism for its role in DNA double-strand break (DSB) repair remains unknown. Here, we show that MTA1 controls p53 stability through inhibiting its ubiquitination by E3 ubiquitin ligases mouse double minute 2 (Mdm2) and constitutive photomorphogenic protein 1 (COP1). The underlying mechanisms involve the ability of MTA1 to compete with COP1 to bind to p53 and/or to destabilize COP1 and Mdm2. Consequently, MTA1 regulates the p53-dependent transcription of p53R2, a direct p53 target gene for supplying nucleotides to repair damaged DNA. Depletion of MTA1 impairs p53-dependent p53R2 transcription and compromises DNA repair. Interestingly, these events could be reversed by MTA1 reintroduction, indicating that MTA1 interjects into the p53-dependent DNA repair. Given the fact that MTA1 is widely up-regulated in human cancers, these findings in conjunction with our earlier finding of a crucial role of MTA1 in DSB repair suggest an inherent role of the MTA1-p53-p53R2 pathway in DNA damage response in cancer cells.
title: Post-Radiation Cavernomas of Spinal Nerve Roots - Case Report and Literature Review of A Rare Condition
Creators: name: Chong, Le Roy
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Musculoskeletal spine
subject: Neuroradiology spine
subject: MR
subject: Education
subject: Treatment effects
subject: Radiation effects
subject: Arteriovenous malformations

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: 1. Present a clinical case report and describe MRI appearances of radiation‐induced cavernous malformations of the cauda equina. 2. Provide a summary and discussion on published cases of this rare condition. 3. Outlinea proposed algorithm to aid...
Generic forms of low Chow rank
Creators: name: Torrance, Douglas A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14N05

description: The least number of products of linear forms that may be added together to obtain a given form is the Chow rank of this form. The Chow rank of a generic form corresponds to the smallest s for which the sth secant variety of the Chow variety fills the ambient space. We show that, except for certain known exceptions, this secant variety has the expected dimension for low values of s.
description: v2: minor changes, 11 pages
Migration of the Mediterranean sea turtles into the Tunisian waters, importance of the tag recoveries as conservation management method
Creators: name: KARAA, Sami
name: BRADAI, Mohamed Nejmeddine
name: MAHMOUD, Sabiha
name: JRIBI, Imed
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2016

description: Data on tag recoveries of 22 loggerhead turtles Caretta caretta (Linnaeus, 1758) and one green turtle Chelonia mydas (Linnaeus, 1758) along the Tunisian coast are reviewed on the basis of published literature and unpublished records since 1988 to 2008. These data showed coincidentally movement patterns of large juvenile and migratory pathways for loggerhead turtles nesting females, primarily for these coming from Greece. The analysis of epibiont of tagged loggerheads supports the migratory character of these turtles performing long distances from their nesting beach to reach Tunisian waters and mainly the gulf of Gabes, considered as feeding and wintering habitat for this species. This area is therefore an important management sub-unit for loggerhead nesting population in the Mediterranean Sea.
Myocardin-dependent Activation of the CArG Box-rich Smooth Muscle γ-Actin Gene: PREFERENTIAL UTILIZATION OF A SINGLE CArG ELEMENT THROUGH FUNCTIONAL ASSOCIATION WITH THE NKX3.1 HOMEODOMAIN PROTEIN
Creators: name: Sun, Qiang
name: Imamura, Masaaki
name: Sethakorn, Nan
name: Long, Xiaochun
name: Miano, Joseph M.
name: Dulin, Nickolai O.
name: Taurin, Sebastien
name: Wang, Da Zhi
name: Zimmer, Warren E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Serum response factor (SRF) is a ubiquitously expressed transcription factor that binds a 10-bp element known as the CArG box, located in the proximal regulatory region of hundreds of target genes. SRF activates target genes in a cell- and context-dependent manner by assembling unique combinations of cofactors over CArG elements. One particularly strong SRF cofactor, myocardin (MYOCD), acts as a component of a molecular switch for smooth muscle cell (SMC) differentiation by activating cytoskeletal and contractile genes harboring SRF-binding CArG elements. Here we report that the human ACTG2 promoter, containing four conserved CArG elements, displays SMC-specific basal activity and is highly induced in the presence of MYOCD. Stable transfection of a non-SMC cell type with Myocd elicits elevations in endogenous Actg2 mRNA. Gel shift and luciferase assays reveal a strong bias for MYOCD-dependent transactivation through CArG2 of the human ACTG2 promoter. Substitution of CArG2 with other CArGs, including a consensus CArG element, fails to reconstitute full MYOCD-dependent ACTG2 promoter stimulation. Mutation of an adjacent binding site for NKX3.1 reduces MYOCD-dependent transactivation of the ACTG2 promoter. Co-immunoprecipitation, glutathione S-transferase pulldown, and luciferase assays show a physical and functional association between MYOCD and NKX3.1; no such functional relationship is evident with the related NKX2.5 transcription factor despite its interaction with MYOCD. These results demonstrate the ability of MYOCD to discriminate among several juxtaposed CArG elements, presumably through its novel partnership with NKX3.1, to optimally transactivate the human ACTG2 promoter.
title: Exploring the Extraordinary in a Journey from Darkroom ‘Dip & Dunk’ to Digital in Rural Zambia.
Creators: name: Strahan, Rodney
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: eHealth
subject: Management
subject: Digital radiography
subject: Teleradiology
subject: Conventional radiography
subject: Computer Applications-Teleradiology
subject: Equipment
subject: Economics
subject: Workforce

description: Learning objectives Background Imaging findings OR Procedure details Conclusion Personal information References
description: Learning objectives: 1. To give an insight into unique imaging problems in resource poor countries. 2. Show the improvement in image quality and service possible with digital...
(4025) William Wallace
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
NF-κB Transcription Factor p50 Critically Regulates Tissue Factor in Deep Vein Thrombosis
Creators: name: Gupta, Kalpna
name: Liu, Ji Guo
name: Chen, Ming
name: Geng, Jian Guo
name: Slungaard, Arne
name: Wang, Jian Guo
name: Wang, Li Jing
name: Pei, Xin Hui
name: Li, Yi Dan
name: Mackman, Nigel
name: Lin, Zhi Lin
name: Wang, Jin Tao
name: Key, Nigel S.
name: Zheng, Sheng Xi
name: Ye, Bu Qing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: NF-κB transcription factors regulate the expression of tissue factor (TF), a principal initiator of the coagulation cascade. Dominant among them is the p50/p65 heterodimer. Here we report that Andrographolide (Andro; a p50 inhibitor) and genetic deletion of p50 attenuated TF activity in stimulated endothelial cells and monocytes/macrophages. Results of the electrophoretic mobility “supershift” assay and chromatin immunoprecipitation demonstrated the direct interaction of the p50/p65 heterodimer with the NF-κB site of the human TF promoter. Andro-treated and p50 null mice both exhibited blunted TF expression and reduced venous thrombosis, which were recapitulated by an anti-murine TF antibody in vivo. Our findings thus indicate that regulation of TF by NF-κB transcription factor p50 is essential for the pathogenesis of deep vein thrombosis and suggest that specific inhibitors of p50, such as Andro, may be therapeutically valuable for preventing and perhaps treating venous thrombosis.
p53 Oligomerization Is Essential for Its C-terminal Lysine Acetylation
Creators: name: Zhang, Yanping
name: Itahana, Yoko
name: Ke, Hengming
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Acetylation of multiple lysine residues in the p53 plays critical roles in the protein stability and transcriptional activity of p53. To better understand how p53 acetylation is regulated, we generated a number of p53 mutants and examined acetylation of each mutant in transfected cells. We found that p53 mutants that are defective in tetramer formation are also defective in C-terminal lysine residue acetylation. Consistently, we found that several cancer-derived p53 mutants that bear mutations in the tetramerization domain cannot form oligomers and are defective in C-terminal lysine acetylation, and these mutants are inactive in p21 transactivation. We demonstrated that the acetyltransferase p300 interacts with and promotes acetylation of wild-type p53 but not with any of the artificially generated or human cancer-derived p53 mutants that are defective in oligomerization. These results, combined with a computer-aided crystal structure analysis, suggest a model in which p53 oligomerization precedes its acetylation by providing docking sites for acetyltransferases.
Use of camouflaging materials in some brachyuran crabs of the Mediterranean infralittoral zone
Creators: name: BEDINI, Roberto
name: CANALI, Maria Grazia
name: BEDINI, Andrea
Publisher: name: Station Biologique de Roscoff (SBR)
Year: 2003

description: In their natural environment, some Brachyura from the shallow water infralittoral zone use several camouflage
 techniques, and many kinds of objects, to conceal their presence on the substratum. In this study we offered to different
 species of Mediterranean Brachyura a wide choice of materials to be used for their camouflaging, in order to verify weather,
 in any of the species considered, there is the tendency to make a precise choice among the objects left at their disposal. We
 observed individuals of Brachyura in an aquarium. The crabs had several types of objects at their disposal, either of a
 biological (animals, animal remains, plants) or non-biological origin (grains of sand and plastic materials), that we had
 previously obtained during open sea dives or removed from specimens caught in traps. We noticed that the tested animals
 exhibited a clear tendency in their choice of objects. Their choice was related to substantial differences in the morphology
 and bio-mechanics of the limbs used for catching and holding objects. Differences in superficial structures on other parts of
 the exoskeleton, such as hooks, bristles and bumps, also influenced the choice. Finally, the choice of some particular
 camouflaging materials can also be related to the characteristics of the habitat of the species, both for biotic or abiotic
 factors.
title: Post surgical MRI breast - review and audit
Creators: name: Muir, Tracey
Publisher: name: The Royal Australian and New Zealand College of Radiologists
Year: 2017
Subjects: subject: Breast
subject: Oncology
subject: MR
subject: Education
subject: Screening
subject: Cancer
subject: Prostheses

description: Purpose Methods and materials Results Conclusion Personal information References
description: Purpose: Breast MRI is being increasingly performed in women who have had post-surgical breast changes, for example, screening for high risk women post reduction/augmentation [1], post operatively prior to re-excision for positive resection margins as well...