cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
High Resolution Observations of Cepheus a
Creators: name: Hughes, V. A.
name: Cohen, R. J.
name: Garrington, S.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: New high resolution 6 cm observations have been made on Cepheus A using MERLIN, and combined with new VLA observations at 3.7 cm. Angular resolution with the latter was 200 mas, and with MERLIN was 60 mas, except for isolated unresolved sources where 33 mas was achieved. Unresolved objects at 60 mas were observed in Sources 2, 3, and in particular 9 which also was not resolved at 33 mas. There is no evidence for any other object as small as this with any significant flux density, although Source 8 was quiescent at the time. The upper limit to the size of Source 9 sets a minimum brightness temperature of 4.3 $\times$ 10$^5$K, and adds credence to a previous suggestion that it is a gyrosynchrotron source. The compact objects of Sources 2 and 3 are thought to be produced by mass outflow from stars, which could be of spectral type B0 - B1, but this is uncertain. There is a discussion regarding the powerhouse for the molecular outflow. Sources 8 and 9, which are the highly time dependent objects, appear at the centre of the disruption of the high density gas, and their estimated high temperature of 10$^7$ - 10$^8$K indicates that they could produce high velocity winds. On the other hand, the OH masers surrounding Source 2(ii) show an outward velocity of about 10 km s${-1}$, which is small, but higher velocity winds could tunnel through adjacent spaces, and even be responsible for the 300 km s${-1}$ bullet of Source 7. An extrapolation of the orthogonals to the IR polarization vectors are not accurate enough to pinpoint the source of the IR radiation, but it is estimated that Sources 2(ii) and 3(d)(ii) could
description: 11 pages + 10 Figures (available by contacting HUGHESV@QUCDN.QUEENSU.CA), PostScripT file, AST-9402-7
The Holographic Shape of Entanglement and Einstein's Equations
Creators: name: Lewkowycz, Aitor
name: Parrikar, Onkar
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study shape-deformations of the entanglement entropy and the modular Hamiltonian for an arbitrary subregion and state (with a smooth dual geometry) in a holographic conformal field theory. More precisely, we study a double-deformation comprising of a shape deformation together with a state deformation, where the latter corresponds to a small change in the bulk geometry. Using a purely gravitational identity from the Hollands-Iyer-Wald formalism together with the assumption of equality between bulk and boundary modular flows for the original, undeformed state and subregion, we rewrite a purely CFT expression for this double deformation of the entropy in terms of bulk gravitational variables and show that it precisely agrees with the Ryu-Takayanagi formula including quantum corrections. As a corollary, this gives a novel, CFT derivation of the JLMS formula for arbitrary subregions in the vacuum, without using the replica trick. Finally, we use our results to give an argument that if a general, asymptotically AdS spacetime satisfies the Ryu-Takayanagi formula for arbitrary subregions, then it must necessarily satisfy the non-linear Einstein equation.
description: 37 pages, 3 figures
Additional file 4: of Molecular diversity and function of jasmintides from Jasminum sambac
Creators: name: Kumari, Geeta
name: Wong, Ka
name: Serra, Aida
name: Shin, Joon
name: Yoon, Ho
name: Siu Sze
name: Tam, James
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Computational Biology

description: Figure S3. NOE cross peak between the HÎ˛s of the each disulfide bond in jS3. (DOCX 171 kb)
Additional file 1 of Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia
Creators: name: Zhu, Nuole
name: Santos-Santos, Miguel
name: Illán-Gala, Ignacio
name: Montal, Victor
name: Estellés, Teresa
name: Barroeta, Isabel
name: Altuna, Miren
name: Arranz, Javier
name: Muñoz, Laia
name: Belbin, Olivia
name: Sala, Isabel
name: Sánchez-Saudinós, Maria Belén
name: Subirana, Andrea
name: Videla, Laura
name: Pegueroles, Jordi
name: Blesa, Rafael
name: Clarimón, Jordi
name: Carmona-Iragui, Maria
name: Fortea, Juan
name: Lleó, Alberto
name: Alcolea, Daniel
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mental Health
subject: Hematology

description: Additional file 1. Diagnostic accuracy of plasma biomarkers and their combination to differentiate between FTD, AD and CN in age-matched group
Additional file 3: of Consistent and reproducible long-term in vitro growth of health and disease-associated oral subgingival biofilms
Creators: name: Velsko, Irina
name: Shaddox, Luciana
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S1. Alpha diversity of healthy and disease site-derived biofilms. (a) Rarefaction curves of Chao1 index (top) and Shannon index (bottom) of all combined generations for healthy and disease site-derived biofilms. (b) Chao1 index (top) and Shannon index (bottom) are significantly different between healthy and disease site-derived biofilms at 20000 reads. (c) Rarefaction curves of Chao1 index (top) and Shannon index (bottom) of healthy (left) and disease (right) site-derived biofilms at each generation. Box plots show 5â 95 percentile. All error bars indicate Âą SD. (PDF 78 kb)
The Cocoon Shocks of Cygnus A: Pressures and Their Implications for the Jets and Lobes
Creators: name: Snios, Bradford
name: Nulsen, Paul E. J.
name: Wise, Michael W.
name: de Vries, Martijn
name: Birkinshaw, Mark
name: Worrall, Diana M.
name: Duffy, Ryan T.
name: Kraft, Ralph P.
name: McNamara, Brian R.
name: Carilli, Chris
name: Croston, Judith H.
name: Edge, Alastair C.
name: Godfrey, Leith E. H.
name: Hardcastle, Martin J.
name: Harris, Daniel E.
name: Laing, Robert A.
name: Mathews, William G.
name: McKean, John P.
name: Perley, Richard A.
name: Rafferty, David A.
name: Young, Andrew J.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We use 2.0 Msec of Chandra observations to investigate the cocoon shocks of Cygnus A and some implications for its lobes and jet. Measured shock Mach numbers vary in the range 1.18-1.66 around the cocoon. We estimate a total outburst energy of $\simeq 4.7\times10^{60}\rm\ erg$, with an age of $\simeq 2 \times 10^{7}\rm\ yr$. The average postshock pressure is found to be $8.6 \pm 0.3 \times 10^{-10}\rm\ erg\ cm^{-3}$, which agrees with the average pressure of the thin rim of compressed gas between the radio lobes and shocks, as determined from X-ray spectra. However, average rim pressures are found to be lower in the western lobe than in the eastern lobe by $\simeq 20\%$. Pressure estimates for hotspots A and D from synchrotron self-Compton models imply that each jet exerts a ram pressure $\gtrsim$ 3 times its static pressure, consistent with the positions of the hotspots moving about on the cocoon shock over time. A steady, one-dimensional flow model is used to estimate jet properties, finding mildly relativistic flow speeds within the allowed parameter range. Models in which the jet carries a negligible flux of rest mass are consistent with with the observed properties of the jets and hotspots. This favors the jets being light, implying that the kinetic power and momentum flux are carried primarily by the internal energy of the jet plasma rather than by its rest mass.
description: Accepted to ApJ, 15 pages, 7 figures, 4 tables
Integrative analysis of the SRC-1 transcriptional networks promoting endocrine resistance in breast cancer
Creators: name: Alacoque L. Browne
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Tamoxifen has been the gold standard treatment of oestrogen receptor positive breast cancer for over 40 years. While its use has significantly improved the outlook for breast cancer patients, up to 40% of patients relapse while on therapy. Steroid receptor co-activator 1 (SRC-1) is a master regulatory protein which is overexpressed in breast cancer. It is associated with high grade tumours, disease recurrence and is an independent predictor of poor disease-free survival. SRC-1 interacts with nuclear receptors and other transcription factors to initiate transcriptional networks and regulate downstream genes which enable the cell to evade therapy. Here, a top-down approach to map out the transcriptional network, regulated by SRC-1 in endocrine resistant breast cancer was taken. RNA-sequencing was performed to identify the transcriptional targets of SRC-1. Molecular characterization identified E2F7, NFIA, DEK, SMAD2, SMARCA1, ASCL1 and TRPS1 as SRC-1-regulated transcription factors/chromatin remodellers. Rapid immunoprecipitation of mass endogenous proteins was employed to uncover SRC-1 interacting partners. STAT1 was confirmed as an SRC-1-interacting transcription factor in endocrine resistant breast cancer. Extended analysis of the SRC-1 effector target gene network revealed genes important in activating cell cycle, proliferation and pathways in cancer. Concerted activity of the SRC-1-mediated network is responsible for driving the highly migratory and proliferative phenotypes of endocrine resistant breast cancer. Moreover, they play a significant role in regulating the undifferentiated tumour population. Upon clinical investigation, high expression of this SRC-1-regulated network is predictive of poor disease-free survival in a tamoxifen-treated patient population. This study provides important insight into a SRC-1-STAT1 complex initiating a transcriptional cascade and regulating key genes involved in endocrine resistance.
Abundances of Mg and K in the atmospheres of turn-off stars in Galactic globular cluster 47 Tucanae
Creators: name: Černiauskas, A.
name: Kučinskas, A.
name: Klevas, J.
name: Dobrovolskas, V.
name: Korotin, S.
name: Bonifacio, P.
name: Ludwig, H. -G.
name: Caffau, E.
name: Steffen, M.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We determined abundances of Mg and K in the atmospheres of 53 (Mg) and 75 (K) turn-off (TO) stars of the Galactic globular cluster 47 Tuc. The obtained abundances, together with those of Li, O, and Na, were used to search for possible relations between the abundances of K and other light elements, Li, O, Na, and Mg, as well as the connections between the chemical composition of TO stars and their kinematical properties. Abundances of Mg and K were determined using archival VLT FLAMES/GIRAFFE spectra, in combination with the 1D NLTE spectral synthesis methodology. Spectral line profiles were computed with the MULTI code, using ATLAS9 stellar model atmospheres. We also utilized 3D hydrodynamical CO5BOLD and 1D hydrostatic LHD model atmospheres for computing 3D-1D LTE abundance corrections for the spectral lines of Mg and K, in order to assess the influence of convection on their formation in the atmospheres of TO stars. The determined average abundance-to-iron ratios and their RMS variations due to star-to-star abundance spreads were $\langle{\rm[Mg/Fe]}\rangle^{\rm 1D NLTE}=0.47\pm0.12$, and $\langle{\rm [K/Fe]}\rangle^{\rm 1D NLTE}=0.39\pm0.09$. Although the data suggest the possible existence of a weak correlation in the [K/Fe]-[Na/Fe] plane, its statistical significance is low. No statistically significant relations between the abundance of K and other light elements were detected. Also, we did not find any significant correlations or anti-correlations between the [Mg/Fe] and [K/Fe] ratios and projected distance from the cluster center. Similarly, no relations between the absolute radial velocities of individual stars and abundances of Mg and K in their atmospheres were detected. The 3D-1D abundance corrections were found to be small ($\leq 0.1$\,dex) for the lines of Mg and K used in this study, thus indicating that the influence of convection on their formation is small.
description: 13 pages, 7 figures. Accepted to A&A
Generalized Sums over Histories for Quantum Gravity I. Smooth Conifolds
Creators: name: Schleich, Kristin
name: Witt, Donald M.
Publisher: name: arXiv
Year: 1993
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: This paper proposes to generalize the histories included in Euclidean functional integrals from manifolds to a more general set of compact topological spaces. This new set of spaces, called conifolds, includes nonmanifold stationary points that arise naturally in a semiclasssical evaluation of such integrals; additionally, it can be proven that sequences of approximately Einstein manifolds and sequences of approximately Einstein conifolds both converge to Einstein conifolds. Consequently, generalized Euclidean functional integrals based on these conifold histories yield semiclassical amplitudes for sequences of both manifold and conifold histories that approach a stationary point of the Einstein action. Therefore sums over conifold histories provide a useful and self-consistent starting point for further study of topological effects in quantum gravity. Postscript figures available via anonymous ftp at black-hole.physics.ubc.ca (137.82.43.40) in file gen1.ps.
description: 81pp., plain TeX, To appear in Nucl. Phys. B
Dust concentration and chondrule formation
Creators: name: Hubbard, Alexander
name: Mac Low, Mordecai-Mark
name: Ebel, Denton S.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Meteoritical and astrophysical models of planet formation make contradictory predictions for dust concentration factors in chondrule forming regions of the solar nebula. Meteoritical and cosmochemical models strongly suggest that chondrules, a key component of the meteoritical record, formed in regions with solids-to-gas mass ratios orders of magnitude above background. However, models of dust grain dynamics in protoplanetary disks struggle to surpass factors of a few outside of very brief windows in the lifetime of the dust grains. Worse, those models do not predict significant concentration factors for dust grains the size of chondrule precursors. We briefly develop the difficulty in concentrating dust particles in the context of nebular chondrule formation and show that the disagreement is sufficiently stark that cosmochemists should explore ideas that might revise the concentration factor requirements downwards.
description: 7 pages, 3 figures, accepted, Meteoritics & Planetary Sciences
Surgical Education: Competitive Factors and Platforms to Trainee Progression and Skill Acquisition
Creators: name: Cuan Harrington
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Background: The predictive validity of cognitive and non-cognitive factors in the development of surgical trainees’ competencies are not well described. Further research gaps exist regarding the impact of competitive personality traits and competitive platforms in the development of skills. We hypothesised that several trainee factors and competitive games platforms are conducive to technical and non-technical skill acquisition. Aims: The primary goal of this dissertation was to determine in essence, true competitive factors in surgical trainee competency. In addition, we aimed to develop gamified simulation resources that motivate deliberate practice in the home environment. Materials and Methods: This research was conducted via multiphase mixed methods approaches, involving premedical/medical students, surgical trainees and trainers. A systematic review and meta-analysis for the predictive validity of selection-criteria to surgical training were performed (chapter #3). A pre-post intervention analysis was conducted to determine the impact of open benchmarking of operative records, and identification of variables influencing operative exposure and competency (chapter #4). Cross-sectional and prospective cohort studies were undertaken to determine predictive variables in the baseline, acquisition and maintenance of laparoscopic skills (chapter #5). A single-blinded randomised controlled trial was implemented to determine the impact of a dedicated laparoscopic ‘serious game’ on the voluntary acquisition of technical skills (chapter #6). A cross-sectional analysis was utilised to assess the face, construct and concurrent validity of a decision-making serious game collaboratively developed (chapter #7). A randomised cross-over study was performed to evaluate the impact of 360° virtual reality videos on attentiveness, engagement and information retention (chapter #8). Results: This research demonstrated the predictive validity of several pre-training factors with future in-training performances. Visuospatial aptitudes and fine-motor experiences were associated with acquisition and maintenance of minimally invasive skills. While competitive personalities provided no performance benefit with psychomotor skills, introducing competitive dynamics and serious games platforms resulted in significant benefits and evidence of validity. Conclusions: A multiplicity of academic and non-academic factors are conducive to technical and non-technical skill progression. In addition, a rivalrous learning environment may promote improved recording behaviours, but competitive personalities were not associated with psychomotor performances. Furthermore, multiple serious games platforms demonstrated evidence of validity and may be conducive to deliberate practice in the home environment.
Lettre de François-Bernard, vicomte de Narbonne-Pelet à Jean-François Séguier, 1778-12-15
Creators: name: vicomte de Narbonne-Pelet, François-Bernard
name: François-Bernard, Vicomte De Narbonne-Pelet
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Nîmes

description: [transcription] Je donne permission aux gens que commettra monsieur Séguier pour extraire la quantité de pierres qui lui sera nécessaire, dans les carrières de notre bois de Lens, paroisses de Montmirat et de Montagnac aux réparations de la Maison Carrée de Nîmes, en ayant attention de leur part d'avertir quand ils y viendront, soit pour les voir, soit pour y travailler, d'en avertir dis-je mes gardes et agents au château de Fontanès, afin qu'ils y veillent aux dommages ou dégradations qu'il convient d'éviter et prévenir dans lesdits bois.

Fait à Nimes le 15 décembre 1778

Le vicomte de Narbonne
description: Source: [lieu de Conservation] Nîmes, Bibliothèque Carré d'Art [cote]ms. 115, fol. 105
description: Source: ark:/12148/btv1b10015824b
Qubit Parity Measurement by Parametric Driving in Circuit QED
Creators: name: Royer, Baptiste
name: Puri, Shruti
name: Blais, Alexandre
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Multi-qubit parity measurements are essential to quantum error correction. Current realizations of these measurements often rely on ancilla qubits, a method that is sensitive to faulty two-qubit gates and which requires significant experimental overhead. We propose a hardware-efficient multi-qubit parity measurement exploiting the bifurcation dynamics of a parametrically driven nonlinear oscillator. This approach takes advantage of the resonator's parametric oscillation threshold which is a function of the joint parity of dispersively coupled qubits, leading to high-amplitude oscillations for one parity subspace and no oscillation for the other. We present analytical and numerical results for two- and four-qubit parity measurements with high-fidelity readout preserving the parity eigenpaces. Moreover, we discuss a possible realization which can be readily implemented with the current circuit QED experimental toolbox. These results could lead to significant simplifications in the experimental implementation of quantum error correction, and notably of the surface code.
description: 8 pages, 3 figures, Supplemental Material (14 pages)
Long standing problem of 210Bi and the realistic neutron-proton effective interaction
Creators: name: Coraggio, L.
name: Covello, A.
name: Gargano, A.
name: Itaco, N.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The odd-odd nucleus 210Bi is studied within the framework of the shell model using effective two-body matrix elements derived from the CD-Bonn nucleon-nucleon potential. The experimental energies of the proton-neutron multiplet ph9/2 ng9/2 are remarkably well reproduced by the theory, which accounts for the 1- state being the ground state instead of the 0- predicted by the Nordheim strong coupling rule. It is shown that the core-polarization effects are crucial to produce this inversion. The similarity between neutron-proton multiplets in the 132Sn and 208Pb regions is discussed in connection with the effective interaction.
description: 4 pages, 3 figures, 1 table, to be published on Physical Review C as a Rapid Communication
Additional file 1 of Microbial co-occurrence complicates associations of gut microbiome with US immigration, dietary intake and obesity
Creators: name: Wang, Zheng
name: Usyk, Mykhaylo
name: Vázquez-Baeza, Yoshiki
name: Chen, Guo-Chong
name: Isasi, Carmen R.
name: Williams-Nguyen, Jessica S.
name: Hua, Simin
name: McDonald, Daniel
name: Thyagarajan, Bharat
name: Daviglus, Martha L.
name: Cai, Jianwen
name: North, Kari E.
name: Wang, Tao
name: Knight, Rob
name: Burk, Robert D.
name: Kaplan, Robert C.
name: Qi, Qibin
Publisher: name: figshare
Year: 2021
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Biotechnology
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 1: Figure S1. Microbial community diversity associated with obesity and US exposure. Figure S2. Beta diversity PERMANOVA analysis for obesity, US exposure, and other co-variates, ranked by R2 Figure S3. Associations of gut microbiota and host obesity (BMI), stratified by: A. Sex; B. Age group (< 55 and > = 55 years); C. Place of birth (US born and non-US born); D. Hispanic origin (Caribbean [Dominican, Cuban, Puerto Rican] and Mainland [Central American, Mexican, South American]) ; E to J. Field Center (Bronx, Chicago, Miami, San Diego). Figure S4. Associations of gut microbiota and US exposure, further stratified by : A. Sex; B. Hispanic origin (Caribbean [Dominican, Cuban, Puerto Rican] and Mainland [Central American, Mexican, South American]); C. Obesity; D. Age group (< 55 and > = 55 years); E to J. Field Center (Bronx, Chicago, Miami, San Diego). Figure S5. Correlation heatmap for the 23 identified bacterial genera associated with both obesity and US exposure. Figure S6. Associations of 23 gut microbial genera with BMI, Body fat percentage and waist circumference. Figure S7. Correlation heatmap for all bacterial genera, using log ratios data and Clostridium as reference. Figure S8. Heatmap for overall dietary quality and individual dietary factor associated with gut microbial genera. Table S1. Characteristics of the study population by US exposure Table S3. Multivariable regression analyses: 23 genera associated with both obesity and US exposure. Table S10. Association of host obesity and US exposure with gut microbiota: species level analyses. Table S11. Conditional analysis for genera associated with both obesity and US exposure Table S12. Levels of gut microbial genera according to host obesity. Table S13. Target US exposure associated enzyme selection: Enrichment test for the annotated enzymes Table S14. Regression analyses: Enrichment test selected key enzymes associated with both US exposure and fiber intake. Table S15. The presence of key enzymes in specific bacteria: Alignment analysis.
The origin of spacetime topology and generalizations of quantum field theory
Creators: name: Yurtsever, Ulvi
Publisher: name: arXiv
Year: 1993
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The research effort reported in this paper is directed, in a broad sense, towards understanding the small-scale structure of spacetime. The fundamental question that guides our discussion is ``what is the physical content of spacetime topology?" In classical physics, if spacetime, $(X, τ)$, has sufficiently regular topology, and if sufficiently many fields exist to allow us to observe all continuous functions on $X$, then this collection of continuous functions uniquely determines both the set of points $X$ and the topology $τ$ on it. To explore the small-scale structure of spacetime, we are led to consider the physical fields (the observables) not as classical (continuous functions) but as quantum operators, and the fundamental observable as not the collection of all continuous functions but the local algebra of quantum field operators. In pursuing our approach further, we develop a number of generalizations of quantum field theory through which it becomes possible to talk about quantum fields defined on arbitrary topological spaces. Our ultimate generalization dispenses with the fixed background topological space altogether and proposes that the fundamental observable should be taken as a lattice (or more specifically a ``frame," in the sense of set theory) of closed subalgebras of an abstract $C^{\ast}$ algebra. Our discussion concludes with the definition and some elementary
description: 23 pages, UCSBTH-92-45
Additional file 1: of Small-scale spatial analysis of intermediate and definitive hosts of Angiostrongylus cantonensis
Creators: name: Hu, Qiu-An
name: Zhang, Yi
name: Guo, Yun-Hai
name: Lv, Shan
name: Xia, Shang
name: Liu, He-Xiang
name: Fang, Yuan
name: Liu, Qin
name: Zhu, Dan
name: Zhang, Qi-Ming
name: Yang, Chun-Li
name: Lin, Guang-Yi
Publisher: name: figshare
Year: 2018
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Multilingual abstracts in the five official working languages of the United Nations. (PDF 261 kb)
The Evaluation of a Pressure Ulcer Prevention Programme (SPUPP) for Older Persons at Risk of Pressure Ulceration, Living in the Community Setting
Creators: name: Shanley, Emer
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Background: There is a potential for increase in the incidence of pressure ulcers (PU) in the older population due to the relationship between ageing and reduced mobility. Prevention of PU’s is a key issue for enhancing health, and education is a means to empower people to take an active role in health promotion. This study set out to develop, validate and evaluate the impact of the Shanley Pressure Ulcer Prevention Programme on older persons’ knowledge of, and attitudes and behaviours towards, PU prevention. Methods: SPUPP is a structured pressure ulcer prevention education programme developed to address the key tenets of PU prevention. The study comprised three phases; phase 1 was the development of SPUPP, phase 2 was the development and psychometric evaluation of the Patient Knowledge of Pressure Ulcer Prevention (KPUP) tool, phase 3 was the evaluation of the SPUPP pre- and post-intervention, using a randomised controlled trial design. Following ethical approval 64 older adults participated in the intervention and completed the KPUP tool pre and post intervention. Knowledge was scored from 0-20. Descriptive analysis was used to summarise, describe and explain the data. Inferential statistics were used to test for possible associations between variables. Results: The participants ranged in age from 70-96 years. Pre intervention mean knowledge scores were 11.68 (SD: 3.09, intervention group) and 11.68 (SD: 3.60, control group). Post intervention the mean knowledge score in the intervention group was 16.87 (SD: 1.87), and control group was 12.40 (SD: 3.2) MD: 4.47 (95% CI: 3.19-5.75; p=0.00001). Positive changes were also noted in the intervention group regarding self-reported health behaviours and attitudes towards PU prevention. Conclusion: The SPUPP impacted positively on knowledge scores, and also positively influenced attitudes and behaviours towards PU prevention. Thus, this research provides useful information regarding the potential to enhance patient involvement in PU prevention.
title: 01_1848
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Additional file 1 of Comparison of 18F-sodium fluoride PET/CT, 18F-fluorocholine PET/CT and diffusion-weighted MRI for the detection of bone metastases in recurrent prostate cancer: a cost-effectiveness analysis in France
Creators: name: Gauthé, Mathieu
name: Zarca, Kevin
name: Aveline, Cyrielle
name: Lecouvet, Frédéric
name: Balogova, Sona
name: Cussenot, Olivier
name: Talbot, Jean-Noël
name: Durand-Zaleski, Isabelle
Publisher: name: figshare
Year: 2020
Subjects: Cell Biology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Science Policy

description: Additional file 1. FLUPROSTIC study design.
Shape-preserving and unidirectional frequency conversion using four-wave mixing Bragg scattering
Creators: name: Christensen, Jesper B.
name: Koefoed, Jacob G.
name: Bell, Bryn A.
name: McKinstrie, Colin J.
name: Rottwitt, Karsten
Publisher: name: arXiv
Year: 2018
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In this work, we investigate the properties of four-wave mixing Bragg scattering in a configuration that employs orthogonally polarized pumps in a birefringent waveguide. This configuration enables a large signal conversion bandwidth, and allows strongly unidirectional frequency conversion as undesired Bragg-scattering processes are suppressed by waveguide birefringence. Moreover, we show that this form of four-wave mixing Bragg scattering preserves the (arbitrary) signal pulse shape, even when driven by pulsed pumps.
description: 11 pages + refs, 5 figures
The Distribution of Galactic Disk Stars in Baade's Window
Creators: name: Paczynski, B.
name: Stanek, K. Z.
name: Udalski, A.
name: Szymanski, M.
name: Kaluzny, J.
name: Kubiak, M.
name: Mateo, M.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The color-magnitude diagram of $ \sim 3 \times 10^5 $ stars obtained for Baade's Window towards the Galactic bulge with the OGLE project reveals a surprisingly narrow main sequence due to galactic disk stars at a distance of $d \sim 2 $ kpc, i.e. at the location of the Sagittarius spiral arm. A more careful analysis indicates there is an excess in the number of disk stars by a factor $\sim 2$ between us and $d \sim 2.5$ kpc and a rapid drop by a factor $\sim 10$ beyond that distance. It is unlikely that the observed structure is an artifact of the interstellar extinction, but careful determination of the extinction is needed before the structure is firmly established. The narrow main sequence extends down to stars as faint as $M_{_V} \approx 7$, i.e. it is composed of old stars. This is not expected in a conventional disk model, or in a conventional model of a spiral structure. However, a strong concentration of old stars towards spiral arms has been noticed in some other galaxies, like M51 (Rix \& Rieke 1993), with the near infrared surface photometry. We have also found that the relative distribution of red clump and red giant stars in the Galactic bulge implies that there is a relatively young stellar population present there.
description: 14 pages, 8 figures, uses AAS LaTeX aaspp.sty macro, PostScript figures available through the anonymous ftp or on request, accepted for publication in the Astronomical Journal
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00185
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: comptes
subject: Chartes de la Bourgogne du Moyen Âge

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00185, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
The Angular Dependence of the Three-Point Correlation Function of the Cosmic Microwave Background Radiation as Predicted by Inflationary Cosmologies
Creators: name: Falk, Toby
name: Rangarajan, Raghavan
name: Srednicki, Mark
Publisher: name: arXiv
Year: 1992
Subjects: subject: Astrophysics (astro-ph)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Inflationary models predict a definite, model independent, angular dependence for the three-point correlation function of $ΔT/T$ at large angles (greater than $\sim 1^\circ$) which we calculate. The overall amplitude is model dependent and generically unobservably small, but may be large in some specific models. We compare our results with other models of nongaussian fluctuations.
description: 7 pages, 3 figures (described but not included, available on request), in Plain Tex, UCSBTH-92-31
Multiwavelength observations of the blazar BL Lacertae: a new fast TeV gamma-ray flare
Creators: name: Abeysekara, A. U.
name: Benbow, W.
name: Bird, R.
name: Brantseg, T.
name: Brose, R.
name: Buchovecky, M.
name: Buckley, J. H.
name: Bugaev, V.
name: Connolly, M. P.
name: Cui, W.
name: Daniel, M. K.
name: Falcone, A.
name: Feng, Q.
name: Finley, J. P.
name: Fortson, L.
name: Furniss, A.
name: Gillanders, G. H.
name: Gunawardhana, I.
name: Hütten, M.
name: Hanna, D.
name: Hervet, O.
name: Holder, J.
name: Hughes, G.
name: Humensky, T. B.
name: Johnson, C. A.
name: Kaaret, P.
name: Kar, P.
name: Kertzman, M.
name: Krennrich, F.
name: Lang, M. J.
name: Lin, T. T. Y.
name: McArthur, S.
name: Moriarty, P.
name: Mukherjee, R.
name: O'Brien, S.
name: Ong, R. A.
name: Otte, A. N.
name: Park, N.
name: Petrashyk, A.
name: Pohl, M.
name: Pueschel, E.
name: Quinn, J.
name: Ragan, K.
name: Reynolds, P. T.
name: Richards, G. T.
name: Roache, E.
name: Rulten, C.
name: Sadeh, I.
name: Santander, M.
name: Sembroski, G. H.
name: Shahinyan, K.
name: Wakely, S. P.
name: Weinstein, A.
name: Wells, R. M.
name: Wilcox, P.
name: Williams, D. A.
name: Zitzer, B.
name: Jorstad, S. G.
name: Marscher, A. P.
name: Lister, M. L.
name: Kovalev, Y. Y.
name: Pushkarev, A. B.
name: Savolainen, T.
name: Agudo, I.
name: Molina, S. N.
name: Gómez, J. L.
name: Larionov, V. M.
name: Borman, G. A.
name: Mokrushina, A. A.
name: Tornikoski, M.
name: Lähteenmäki, A.
name: Chamani, W.
name: Enestam, S.
name: Kiehlmann, S.
name: Hovatta, T.
name: Smith, P. S.
name: Pontrelli, P.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Combined with very-long-baseline interferometry measurements, the observations of fast TeV gamma-ray flares probe the structure and emission mechanism of blazar jets. However, only a handful of such flares have been detected to date, and only within the last few years have these flares been observed from lower-frequency-peaked BL~Lac objects and flat-spectrum radio quasars. We report on a fast TeV gamma-ray flare from the blazar BL~Lacertae observed by VERITAS, with a rise time of $\sim$2.3~hr and a decay time of $\sim$36~min. The peak flux above 200 GeV is $(4.2 \pm 0.6) \times 10^{-6} \;\text{photon} \;\text{m}^{-2}\; \text{s}^{-1}$ measured with a 4-minute-binned light curve, corresponding to $\sim$180\% of the flux which is observed from the Crab Nebula above the same energy threshold. Variability contemporaneous with the TeV gamma-ray flare was observed in GeV gamma-ray, X-ray, and optical flux, as well as in optical and radio polarization. Additionally, a possible moving emission feature with superluminal apparent velocity was identified in VLBA observations at 43 GHz, potentially passing the radio core of the jet around the time of the gamma-ray flare. We discuss the constraints on the size, Lorentz factor, and location of the emitting region of the flare, and the interpretations with several theoretical models which invoke relativistic plasma passing stationary shocks.
description: 23 pages, 9 figures
Bounds for the covariance of functions of infinite variance stable random variables with applications to central limit theorems and wavelet-based estimation
Creators: name: Pipiras, Vladas
name: Taqqu, Murad S.
name: Abry, Patrice
Publisher: name: arXiv
Year: 2007
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We establish bounds for the covariance of a large class of functions of infinite variance stable random variables, including unbounded functions such as the power function and the logarithm. These bounds involve measures of dependence between the stable variables, some of which are new. The bounds are also used to deduce the central limit theorem for unbounded functions of stable moving average time series. This result extends the earlier results of Tailen Hsing and the authors on central limit theorems for bounded functions of stable moving averages. It can be used to show asymptotic normality of wavelet-based estimators of the self-similarity parameter in fractional stable motions.
description: Published in at http://dx.doi.org/10.3150/07-BEJ6143 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm)
The Dependence of the Peak Velocity of High-Speed Solar Wind Streams as Measured in the Ecliptic by ACE and the STEREO satellites on the Area and Co-Latitude of their Solar Source Coronal Holes
Creators: name: Hofmeister, Stefan J.
name: Veronig, Astrid
name: Temmer, Manuela
name: Vennerstrom, Susanne
name: Heber, Bernd
name: Vršnak, Bojan
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We study the properties of 115 coronal holes in the time-range from 2010/08 to 2017/03, the peak velocities of the corresponding high-speed streams as measured in the ecliptic at 1 AU, and the corresponding changes of the Kp index as marker of their geo-effectiveness. We find that the peak velocities of high-speed streams depend strongly on both the ar- eas and the co-latitudes of their solar source coronal holes with regard to the heliospheric latitude of the satellites. Therefore, the co-latitude of their source coronal hole is an im- portant parameter for the prediction of the high-speed stream properties near the Earth. We derive the largest solar wind peak velocities normalized to the coronal hole areas for coronal holes located near the solar equator, and that they linearly decrease with increas- ing latitudes of the coronal holes. For coronal holes located at latitudes & 60°, they turn statistically to zero, indicating that the associated high-speed streams have a high chance to miss the Earth. Similar, the Kp index per coronal hole area is highest for the coronal holes located near the solar equator and strongly decreases with increasing latitudes of the coronal holes. We interpret these results as an effect of the three-dimensional propaga- tion of high-speed streams in the heliosphere, i.e., high-speed streams arising from coro- nal holes near the solar equator propagate in direction towards and directly hit the Earth, whereas solar wind streams arising from coronal holes at higher solar latitudes only graze or even miss the Earth.
SRC-1 Mediates DNA Methylation Driving a De-Differentiated State in Endocrine Resistant Breast Cancer by Recruiting a Methyl Regulatory Complex
Creators: name: Ward, Elspeth
Publisher: name: Royal College of Surgeons in Ireland
Year: 2019
Subjects: Uncategorized

description: Breast cancer progression occurs through the accumulation of genetic and epigenetic abnormalities. Hormone receptor positive breast cancer is driven by the estrogen receptor whose expression is indicative of good prognosis. Despite the clinical utility of endocrine therapies for estrogen receptor positive breast cancer, up to 40% of patients eventually develop resistance, leading to disease progression. The molecular determinants that drive this adaptation to treatment remain poorly understood with genetic and epigenetic modifications implicated. Increasing evidence suggests that aberrant DNA hyper-methylation of tumour suppressors and hypo-methylation of oncogenes driving dysregulation of differentiation/developmental genes may represent a major mechanism underlying tumour progression. Methylome aberrations have been found to drive cancer growth yet the functional role and mechanism of these epi-mutations in drug resistance are poorly elucidated. In this study enhanced global hyper-methylation in endocrine resistant cell models and patient metastasis relative to sensitive parent cells and matched primary breast tumour respectively was observed. A multi-omic sequencing approach combining methylome analysis and transcriptional profiling was utilised. This demonstrated that SRC-1, contrary to its classic role as an estrogen receptor coactivator is essential for epigenetic remodelling of key pro-differentiation genes. This pro-differentiation gene set was shown in vitro to have several tumour suppressor gene characteristics, whose repression aids de-differentiated aggressive disease phenotype. SRC-1 was shown to regulate the methylation status of this pro-differentiation gene set by recruiting a methyl complex including MBD2, MeCP2 and HDAC2. Analysis of human breast tumours demonstrated that low expression of this pro-differentiation gene set significantly associated with poor clinical outcome in tamoxifen treated population and that the re-activation of these genes in vitro and ex vivo reverses the aggressive phenotype. This work demonstrates that SRC-1 via epigenetic remodelling mechanics is a ‘high level’ regulator of the poorly differentiated state in estrogen receptor positive xiii breast cancer. Collectively these data revealed an epigenetic reprograming pathway, whereby concerted differential DNA methylation is potentiated by SRC-1 in the endocrine resistant setting.
Algebraic approach to quantum field theory on non-globally-hyperbolic spacetimes
Creators: name: Yurtsever, Ulvi
Publisher: name: arXiv
Year: 1993
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The mathematical formalism for linear quantum field theory on curved spacetime depends in an essential way on the assumption of global hyperbolicity. Physically, what lie at the foundation of any formalism for quantization in curved spacetime are the canonical commutation relations, imposed on the field operators evaluated at a global Cauchy surface. In the algebraic formulation of linear quantum field theory, the canonical commutation relations are restated in terms of a well-defined symplectic structure on the space of smooth solutions, and the local field algebra is constructed as the Weyl algebra associated to this symplectic vector space. When spacetime is not globally hyperbolic, e.g. when it contains naked singularities or closed timelike curves, a global Cauchy surface does not exist, and there is no obvious way to formulate the canonical commutation relations, hence no obvious way to construct the field algebra. In a paper submitted elsewhere, we report on a generalization of the algebraic framework for quantum field theory to arbitrary topological spaces which do not necessarily have a spacetime metric defined on them at the outset. Taking this generalization as a starting point, in this paper we give a prescription for constructing the field algebra of a (massless or massive) Klein-Gordon field on an arbitrary background spacetime. When spacetime is globally hyperbolic, the theory defined by our construction coincides with the ordinary Klein-Gordon field theory on a
description: 21 pages, UCSBTH-92-43