cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dose effects in behavioural treatment of post-stroke aphasia: a systematic review and meta-analysis
Creators: name: Harvey, Samuel
name: Carragher, Marcella
name: Dickey, Michael Walsh
name: Pierce, John
name: Rose, Miranda
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Purpose: Aphasia is a debilitating chronic acquired language disorder that impacts heavily on a person’s life. Behavioural treatments aim to remediate language processing skills or to enhance communication between the person with aphasia and others, and a number of different treatments are efficacious. However, it is unclear how much of a particular treatment a person needs in order to optimise recovery of language and communication skills following stroke. Materials and methods: Systematic search for and meta-analysis of experimental studies that directly compared different amounts of the same behavioural aphasia treatment, following PRISMA guidelines. Results: Treatment dose research in aphasia is an emerging area. Just six studies comparing different doses of the same intervention met all criteria for inclusion. Evidence from these studies was synthesised and meta-analysed, where possible. Meta-analyses were inconclusive due to limited data; however, there are indications that suggest increased dose may confer greater improvement on language and communication measures, but with diminishing returns over time. Aphasia severity and chronicity may affect dose–response relationships. Conclusions: There is currently insufficient evidence to determine the effect of dose on treatment response. A dedicated and coordinated research agenda is required to systematically explore dose–response relationships in post-stroke aphasia interventions. A video abstract is available in the Supplementary Material.Implications for rehabilitation The investigation of the effect of dose on treatment outcomes in post-stroke aphasia is an emerging research area with few studies reporting comparison of different amounts of the same intervention. In the acute phase of recovery following stroke, higher doses of treatment provided over short periods may not be preferable, tolerable, or superior to lower doses of the same treatment. In the chronic phase, providing additional blocks of treatment may confer additional benefit for some people with aphasia but with diminishing returns. People with chronic aphasia can achieve and maintain significant gains in picture naming after a relatively brief period of high-dose treatment.
Additional file 1 of Molecular characterization of a bovine adenovirus type 7 (Bovine Atadenovirus F) strain isolated from a systemically infected calf in Germany
Creators: name: Jesse, Sonja T.
name: Ciurkiewicz, Malgorzata
name: Siesenop, Ute
name: Spitzbarth, Ingo
name: Osterhaus, A. D. M. E.
name: Baumgärtner, Wolfgang
name: Ludlow, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. Diagnostic tests performed on frozen tissue collected during necropsy of a calf.
Dose effects in behavioural treatment of post-stroke aphasia: a systematic review and meta-analysis
Creators: name: Harvey, Samuel
name: Carragher, Marcella
name: Dickey, Michael Walsh
name: Pierce, John
name: Rose, Miranda
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 44
subject: Human society

description: Purpose: Aphasia is a debilitating chronic acquired language disorder that impacts heavily on a person’s life. Behavioural treatments aim to remediate language processing skills or to enhance communication between the person with aphasia and others, and a number of different treatments are efficacious. However, it is unclear how much of a particular treatment a person needs in order to optimise recovery of language and communication skills following stroke. Materials and methods: Systematic search for and meta-analysis of experimental studies that directly compared different amounts of the same behavioural aphasia treatment, following PRISMA guidelines. Results: Treatment dose research in aphasia is an emerging area. Just six studies comparing different doses of the same intervention met all criteria for inclusion. Evidence from these studies was synthesised and meta-analysed, where possible. Meta-analyses were inconclusive due to limited data; however, there are indications that suggest increased dose may confer greater improvement on language and communication measures, but with diminishing returns over time. Aphasia severity and chronicity may affect dose–response relationships. Conclusions: There is currently insufficient evidence to determine the effect of dose on treatment response. A dedicated and coordinated research agenda is required to systematically explore dose–response relationships in post-stroke aphasia interventions. A video abstract is available in the Supplementary Material.Implications for rehabilitation The investigation of the effect of dose on treatment outcomes in post-stroke aphasia is an emerging research area with few studies reporting comparison of different amounts of the same intervention. In the acute phase of recovery following stroke, higher doses of treatment provided over short periods may not be preferable, tolerable, or superior to lower doses of the same treatment. In the chronic phase, providing additional blocks of treatment may confer additional benefit for some people with aphasia but with diminishing returns. People with chronic aphasia can achieve and maintain significant gains in picture naming after a relatively brief period of high-dose treatment.
Dose effects in behavioural treatment of post-stroke aphasia: a systematic review and meta-analysis
Creators: name: Harvey, Samuel
name: Carragher, Marcella
name: Dickey, Michael Walsh
name: Pierce, John
name: Rose, Miranda
Publisher: name: La Trobe
Year: 2022

description: Purpose: Aphasia is a debilitating chronic acquired language disorder that impacts heavily on a person’s life. Behavioural treatments aim to remediate language processing skills or to enhance communication between the person with aphasia and others, and a number of different treatments are efficacious. However, it is unclear how much of a particular treatment a person needs in order to optimise recovery of language and communication skills following stroke. Materials and methods: Systematic search for and meta-analysis of experimental studies that directly compared different amounts of the same behavioural aphasia treatment, following PRISMA guidelines. Results: Treatment dose research in aphasia is an emerging area. Just six studies comparing different doses of the same intervention met all criteria for inclusion. Evidence from these studies was synthesised and meta-analysed, where possible. Meta-analyses were inconclusive due to limited data; however, there are indications that suggest increased dose may confer greater improvement on language and communication measures, but with diminishing returns over time. Aphasia severity and chronicity may affect dose–response relationships. Conclusions: There is currently insufficient evidence to determine the effect of dose on treatment response. A dedicated and coordinated research agenda is required to systematically explore dose–response relationships in post-stroke aphasia interventions. A video abstract is available in the Supplementary Material.Implications for rehabilitation The investigation of the effect of dose on treatment outcomes in post-stroke aphasia is an emerging research area with few studies reporting comparison of different amounts of the same intervention. In the acute phase of recovery following stroke, higher doses of treatment provided over short periods may not be preferable, tolerable, or superior to lower doses of the same treatment. In the chronic phase, providing additional blocks of treatment may confer additional benefit for some people with aphasia but with diminishing returns. People with chronic aphasia can achieve and maintain significant gains in picture naming after a relatively brief period of high-dose treatment.
Additional file 1 of Exploring nurses' experiences of social media and in-person educational interventions for professional development: a qualitative study
Creators: name: Kazemi, Seyedeh-Somayeh
name: Tavafian, Sedigheh-Sadat
name: Hidarnia, Alireza
name: Montazeri, Ali
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy

description: Additional file 1.
Mitochondrial protein gene expression and the oxidative phosphorylation pathway associated with feed efficiency and energy balance in dairy cattle
Creators: name: Dorji, Jigme
name: MacLeod, Iona
name: Chamberlain, Amanda
name: Vander Jagt, CJ
name: Ho, PN
name: Khansefid, Majid
name: Mason, BA
name: Prowse-Wilkins, CP
name: Marett, LC
name: Wales, WJ
name: Cocks, Benjamin
name: Pryce, Jennie
name: Daetwyler, Hans
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 30
subject: Agricultural, veterinary and food sciences
classificationCode: 3003
subject: Animal production
classificationCode: 3006
subject: Food sciences
classificationCode: 3009
subject: Veterinary sciences
subject: FOS: Veterinary sciences

description: No description supplied
A natriuretic peptide from Arabidopsis thaliana (AtPNP-A) can modulate catalase 2 activity
Creators: name: Turek, Ilona
name: Wheeler, Janet
name: Bartels, S
name: Szczurek, J
name: Wang, Yu Hua
name: Taylor, Philip
name: Gehring, C
name: Irving, Helen
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3108
subject: Plant biology

description: © 2020, The Author(s). Analogues of vertebrate natriuretic peptides (NPs) present in plants, termed plant natriuretic peptides (PNPs), comprise a novel class of hormones that systemically affect salt and water balance and responses to plant pathogens. Several lines of evidence indicate that Arabidopsis thaliana PNP (AtPNP-A) affects cellular redox homeostasis, which is also typical for the signaling of its vertebrate analogues, but the molecular mechanism(s) of this effect remains elusive. Here we report identification of catalase 2 (CAT2), an antioxidant enzyme, as an interactor of AtPNP-A. The full-length AtPNP-A recombinant protein and the biologically active fragment of AtPNP-A bind specifically to CAT2 in surface plasmon resonance (SPR) analyses, while a biologically inactive scrambled peptide does not. In vivo bimolecular fluorescence complementation (BiFC) showed that CAT2 interacts with AtPNP-A in chloroplasts. Furthermore, CAT2 activity is lower in homozygous atpnp-a knockdown compared with wild type plants, and atpnp-a knockdown plants phenocopy CAT2-deficient plants in their sensitivity to elevated H2O2, which is consistent with a direct modulatory effect of the PNP on the activity of CAT2 and hence H2O2 homeostasis. Our work underlines the critical role of AtPNP-A in modulating the activity of CAT2 and highlights a mechanism of fine-tuning plant responses to adverse conditions by PNPs.
Scorpiops (Euscorpiops) phatoensis Kovařík, Lowe, Stockmann & Št'áhlavský 2020
Creators: name: Lourenço, Wilson R.
name: Ythier, Eric
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Scorpiones
Scorpiopidae
Scorpiops
Scorpiops phatoensis

description: - S. (Euscorpiops) phatoensis Kovařík, Lowe, Stockmann & Št’áhlavský, 2020
Thailand
description: Published as part of Lourenço, Wilson R. & Ythier, Eric, 2022, A new species of the genus Scorpiops Peters, 1861, subgenus Euscorpiops Vachon, 1980 from Laos (Scorpiones: Scorpiopidae), pp. 1-9 in Faunitaxys 10 (27) on page 3, DOI: 10.57800/faunitaxys-10(27), http://zenodo.org/record/15352467
title: Library Partnerships to Support Data Analytics Engineering Programs
Creators: name: Mann, Wendy
name: Calcagno, Theresa
name: Kermer, Deborah Ann
Publisher: name: 126th Annual Conference of the American Society for Engineering Education
Year: 2019

description: In the last decade, the number of graduate programs in Data Analytics has grown exponentially. Academic libraries have had to, or will need to, determine how to support the growing student population in this new area of academia, as well as acquire new resources and develop new services and tools for analytics students. Data Analytics and Data Science programs are particularly challenging to support because they are trans-disciplinary—incorporating areas such as statistics, computer science and business. At George Mason University (Mason) the Data Analytics Engineering (DAEN) program is a master’s degree program in the Volgenau School of Engineering. This program started in 2014 and enrolls students in 10 different concentrations including business analytics, cyber security analytics, financial engineering, predictive analytics and more. This paper discusses how the Engineering Librarian collaborated with the Mason Libraries’ Digital Scholarship Center (DiSC) to identify and develop ways to help meet the needs of this unique group of students.
title: Milton Barnes to Robert L. Allison, May 2, 1862.
Creators: name: Barnes, Milton
Publisher: name: George Mason University
Year: 2011
Subjects: subject: Railroad travel
subject: Frémont, John Charles, 1813-1890
subject: Ashby, Turner, 1828-1862

description: Public domain. There are no known use restrictions.
description: Letter to Rhoda Barnes' grandfather Robert L. Allison from Milton Barnes. Barnes recounts his railroad journey on the B & O from Ohio to Winchester, Virginia and then his 35 mile journey on foot from Winchester, Virginia, to his regiment in New Market, Virginia. He mentions seeing Major General John C. Fremont during his journey to Virginia and he mentions Fremonts present location in Staunton, Virginia. Along with the letter Barnes has sent "Confederate scrip" for Mr. Allison and suggests paying any debts to Successionist friends with it.
Additional file 1 of Molecular characterization of endophytic and ectophytic plant growth promoting bacteria isolated from tomato plants (Solanum lycopersicum L.) grown in different soil types
Creators: name: Helal, Donia S.
name: El-khawas, Hussein
name: Elsayed, Tarek R.
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1: Table S1. Antibiotics and secondary metabolites related genes as detected in the genome sequences of closely related genomes to the isolates obtained from this study.
A natriuretic peptide from Arabidopsis thaliana (AtPNP-A) can modulate catalase 2 activity
Creators: name: Turek, Ilona
name: Wheeler, Janet
name: S Bartels
name: J Szczurek
name: Wang, Yu Hua
name: Taylor, Phil
name: C Gehring
name: Irving, Helen
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, The Author(s). Analogues of vertebrate natriuretic peptides (NPs) present in plants, termed plant natriuretic peptides (PNPs), comprise a novel class of hormones that systemically affect salt and water balance and responses to plant pathogens. Several lines of evidence indicate that Arabidopsis thaliana PNP (AtPNP-A) affects cellular redox homeostasis, which is also typical for the signaling of its vertebrate analogues, but the molecular mechanism(s) of this effect remains elusive. Here we report identification of catalase 2 (CAT2), an antioxidant enzyme, as an interactor of AtPNP-A. The full-length AtPNP-A recombinant protein and the biologically active fragment of AtPNP-A bind specifically to CAT2 in surface plasmon resonance (SPR) analyses, while a biologically inactive scrambled peptide does not. In vivo bimolecular fluorescence complementation (BiFC) showed that CAT2 interacts with AtPNP-A in chloroplasts. Furthermore, CAT2 activity is lower in homozygous atpnp-a knockdown compared with wild type plants, and atpnp-a knockdown plants phenocopy CAT2-deficient plants in their sensitivity to elevated H2O2, which is consistent with a direct modulatory effect of the PNP on the activity of CAT2 and hence H2O2 homeostasis. Our work underlines the critical role of AtPNP-A in modulating the activity of CAT2 and highlights a mechanism of fine-tuning plant responses to adverse conditions by PNPs.
Fungus-originated genes in the genomes of cereal and pasture grasses acquired through ancient lateral transfer
Creators: name: H Shinozuka
name: M Shinozuka
name: Vries, Ellen De
name: Sawbridge, Tim
name: Spangenberg, German
name: Cocks, Benjamin
Publisher: name: La Trobe
Year: 2020
Subjects: Uncategorized

description: © 2020, The Author(s). Evidence for ancestral gene transfer between Epichloë fungal endophyte ancestors and their host grass species is described. From genomes of cool-season grasses (the Poeae tribe), two Epichloë-originated genes were identified through DNA sequence similarity analysis. The two genes showed 96% and 85% DNA sequence identities between the corresponding Epichloë genes. One of the genes was specific to the Loliinae sub-tribe. The other gene was more widely conserved in the Poeae and Triticeae tribes, including wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.). The genes were independently transferred during the last 39 million years. The transferred genes were expressed in plant tissues, presumably retaining molecular functions. Multiple gene transfer events between the specific plant and fungal lineages are unique. A range of cereal crops is included in the Poeae and Triticeae tribes, and the Loliinae sub-tribe is consisted of economically important pasture and forage crops. Identification and characterisation of the 'natural' adaptation transgenes in the genomes of cereals, and pasture and forage grasses, that worldwide underpin the production of major foods, such as bread, meat, and milk, may change the ‘unnatural’ perception status of transgenic and gene-edited plants.
Supplementary document for Topological enhancement of evanescent field localization in all-dielectric metasurfaces - 6413573.pdf
Creators: name: Lepeshov, Sergey
name: Yesmantovich, Maksim
name: Bogdanov, Andrey
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Revised version of Supplementary Information
A physical activity coaching intervention can improve and maintain physical activity and health-related outcomes in adult ambulatory hospital patients: the Healthy4U-2 randomised controlled trial
Creators: name: Barrett, Stephen
name: Begg, Stephen
name: O'Halloran, Paul
name: Kingsley, Michael
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Abstract Background The Healthy 4 U-2 study sought to evaluate the effect of a twelve-week, physical activity (PA) coaching intervention for changes and maintenance in PA, anthropometrics and health-related outcomes in adults presenting to an ambulatory hospital clinic. Methods One hundred and twenty insufficiently active adults were recruited from an ambulatory hospital clinic and randomised to an intervention group that received an education session and five 20-min telephone sessions of PA coaching, or to a control group that received the education session only. ActiGraph GT3X accelerometers were used to measure moderate-to-vigorous physical activity (MVPA) at baseline, post-intervention (3-months) and follow-up (9-months). Secondary outcome measures (anthropometrics, PA self-efficacy, and health-related quality of life) were also assessed at the three time points. Results At baseline, the mean age and body mass index of participants were 53 ± 8 years and 31 ± 4 kg/m2, respectively. Relative to control, the intervention group increased objectively measured MVPA at post-intervention (p
Recruiting stigmatised populations and managing negative commentary via social media: a case study of recruiting older LGBTI research participants in Australia
Creators: name: Waling, Andrea
name: Lyons, Anthony
name: Alba, Beatrice
name: Minichiello, Victor
name: Barrett, Catherine
name: M Hughes
name: K Fredriksen-Goldsen
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: In this paper we explore methodological considerations for recruiting stigmatised populations online. Advertising for research participants via social networking sites (SNS) has increasingly become a tool of choice for both quantitative and qualitative researchers. However, such recruitment practices pose a range of challenges for researchers, especially in handling negative commentary such as trolling and its potential negative impact on prospective research participants. Using a case study involving a project on the health and well-being of older lesbian, gay, bisexual, transgender and intersex (LGBTI) people in Australia, we outline the types of commentary we received on our advertising campaign, as well as our strategies for managing such commentary. We seek to offer ways in which researchers working with stigmatised populations, as well as controversial issues that may attract hostile attention, can effectively manage participant recruitment as researchers increasingly utilise online technologies for recruitment advertising.
Additional file 2 of Molecular characterization of a bovine adenovirus type 7 (Bovine Atadenovirus F) strain isolated from a systemically infected calf in Germany
Creators: name: Jesse, Sonja T.
name: Ciurkiewicz, Malgorzata
name: Siesenop, Ute
name: Spitzbarth, Ingo
name: Osterhaus, A. D. M. E.
name: Baumgärtner, Wolfgang
name: Ludlow, Martin
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 2. Primers sequences used in this study.
Scorpiops (Euscorpiops) prasiti Kovařík, Lowe, Stockmann & Št'áhlavský 2020
Creators: name: Lourenço, Wilson R.
name: Ythier, Eric
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Scorpiones
Scorpiopidae
Scorpiops
Scorpiops prasiti

description: - S. (Euscorpiops) prasiti Kovařík, Lowe, Stockmann & Št’áhlavský, 2020
Thailand
description: Published as part of Lourenço, Wilson R. & Ythier, Eric, 2022, A new species of the genus Scorpiops Peters, 1861, subgenus Euscorpiops Vachon, 1980 from Laos (Scorpiones: Scorpiopidae), pp. 1-9 in Faunitaxys 10 (27) on page 3, DOI: 10.57800/faunitaxys-10(27), http://zenodo.org/record/15352467
Multidisciplinary, exercise-based oncology rehabilitation programs improve patient outcomes but their effects on healthcare service-level outcomes remain uncertain: a systematic review.
Creators: name: Dennett, Amy
name: Sarkies, Mitchell
name: Shields, Nora
name: Peiris, Casey
name: Cylie Williams
name: Taylor, Nicholas
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: QuestionWhat is the effect of multidisciplinary, exercise-based, group oncology rehabilitation programs on healthcare service outcomes and patient-level outcomes, including quality of life and physical and psychosocial function?DesignSystematic review with meta-analysis of randomised controlled trials.ParticipantsAdults diagnosed with cancer.InterventionMultidisciplinary, group-based rehabilitation that includes exercise for cancer survivors.Outcome measuresPrimary outcomes related to health service delivery, including costs, hospitalisations and healthcare service utilisation. Secondary outcomes were patient-level measures, including: the European Organisation for Research and Treatment of Cancer Quality-of-life Questionnaire, 30-second timed sit to stand and the Hospital Anxiety and Depression Scale. The evidence was evaluated using the PEDro Scale and the Grades of Research, Assessment, Development and Evaluation (GRADE) approach.ResultsSeventeen trials (1,962 participants) were included. There was uncertainty about the effect of multidisciplinary, exercise-based rehabilitation on healthcare service outcomes, as only one trial reported length of stay and reported wide confidence intervals (MD 2.4 days, 95% CI -3.1 to 7.8). Multidisciplinary, exercise-based rehabilitation improved muscle strength (1RM chest press MD 3.6 kg, 95% CI 0.4 to 6.8; 1RM leg press MD 19.5 kg, 95% CI 12.3 to 26.8), functional strength (30-second sit to stand MD 6 repetitions, 95% CI 3 to 9) and reduced depression (MD -0.7 points, 95% CI -1.2 to -0.1) compared to usual care. There was uncertainty whether multidisciplinary rehabilitation programs are more effective when delivered early versus late or more effective than exercise alone. Adherence was typically high (mean weighted average 76% sessions attended) with no major and few minor adverse events reported.ConclusionMultidisciplinary, exercise-based oncology rehabilitation programs improve some patient-level outcomes compared with usual care. Further evidence from randomised trials to determine their effect at a healthcare service level are required if these programs are to become part of standard care.Trial registrationPROSPERO CRD42019130593.
title: CHOOSING A ROAD LESS TRAVELLED: PORTRAYALS OF SOCIAL STUDIES TEACHERS INTEGRATING INQUIRY-BASED INSTRUCTION
Creators: name: (:Unkn) Unknown
Publisher: name: George Mason University
Year: 2019

description: Inquiry-based instruction has a rich tradition in social studies education; scholars have long advocated for an inquiry-based classroom in which the student is actively and directly involved in the construction and testing of knowledge, with a reduced emphasis on the teacher as the keeper and transmitter of knowledge. Proponents of inquiry-based instruction argue that it should be a part of social studies education at all grade levels as it holds great promise in promoting problem solving, creativity, collaboration, and critical thinking in authentic learning environments. The overarching purpose of this multiple case study was to explore how three social studies teachers conceptualized and engaged their students in inquiry-based instruction. Factors influencing and supporting their use of inquiry-based instruction was also explored. Data collection included semi-structured interviews, observations, teaching materials, professional development materials, and newspaper clippings. Themes emerging from a thematic analysis indicated that teachers conceptualized inquiry-based instruction as (a) an empowering process which motivates students to drive their own learning in real-world settings; (b) a learning process which stimulates students to “want to know more” by shifting wondering, questioning, and critical thinking to them; and (c) a real world decision-making/investigative process which helps students develop ownership of learning. Key findings were that (a) context matters: all three teachers carried out the inquiry process through employing different inquiry-based models or frameworks; teachers’ use of inquiry were supported by a school culture and context that provided autonomy and stimulus; and teachers molded their inquiry-based instruction around their students’ interests and the context in which they teach; (b) authentic inquiry - based instruction requires certain essential features; (c) teacher learning trajectory involves persistence and gradual learning by doing; and (d) future learning environments will seek to make learning more empowering. Implications and recommendations were: (a) empowering teachers with autonomy; (b) helping teachers internalize the concepts of authentic inquiry-based instruction; (c) immersing teachers in learning by doing (c) setting the stage for 21st century learning environments.
Cheleuet, mem breder, cheleuet ur chanson
Creators: name: Musée National Des Arts Et Traditions Populaires (Paris)
name: Centre D'ethnologie Française
Publisher: name: École des Hautes Études en Sciences Sociales; Institut  interdisciplinaire d'anthropologie du contemporain (Paris); Laboratoire d'anthropologie et d'histoire de l'institution de la culture (Paris)
Year: 2024

Abstract
title: Letter and newsclipping: C. Harrison Mann, Jr. to Herman J. Obermayer, April 1, 1965
Creators: name: Mann, Charles Harrison, Jr., 1908-1977
Publisher: name: George Mason University
Year: 2005
Subjects: subject: Obermayer, Herman J.
subject: News clipping
subject: Vietnam

description: News clipping: memograph copy, 11" x 8.5" (29.7 cm x 21.6 cm); Letter: typescript unsigned, 11" x 8.5" (27.9 cm x 21.6 cm)
description: Newspaper editorial entitled "The Same Mistake" regarding the United States involvement in Vietnam. Mann's letter is responds opposing the tone of the editorial as "pro-communist." C. Harrison Mann, Jr. Collection 2.19
Additional file 1 of Utilisation of supplementary prenatal screening and diagnostics in Germany: cross-sectional study using data from the KUNO Kids Health Study
Creators: name: Mayer, Johanna
name: Brandstetter, Susanne
name: Tischer, Christina
name: Seelbach-Göbel, Birgit
name: Malfertheiner, Sara Fill
name: Melter, Michael
name: Kabesch, Michael
name: Apfelbacher, Christian
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: Additional file 1.
The Effect of Mianserin on Lifespan of Caenorhabditis elegans is Abolished by Glucose
Creators: name: Almotayri, Abdullah
name: Thomas, Jency
name: Munasinghe, Mihiri
name: Jois, Markandeya
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: Background:
The antidepressant mianserin has been shown to extend the lifespan of Caenorhabditis elegans (C. elegans), a well-established model organism used in aging research. The extension of lifespan in C. elegans was shown to be dependent on increased expression of the scaffolding protein (ANK3/unc-44). In contrast, antidepressant use in humans is associated with an increased risk of death. The C. elegans in the laboratory are fed Escherichia coli (E. coli), a diet high in protein and low in carbohydrate, whereas a typical human diet is high in carbohydrates. We hypothesized that dietary carbohydrates might mitigate the lifespan-extension effect of mianserin.

Objective:
To investigate the effect of glucose added to the diet of C. elegans on the lifespan-extension effect of mianserin.

Methods:
Wild-type Bristol N2 and ANK3/unc-44 inactivating mutants were cultured on agar plates containing nematode growth medium and fed E. coli. Treatment groups included (C) control, (M50) 50 μM mianserin, (G) 73 mM glucose, and (M50G) 50 μM mianserin and 73 mM glucose. Lifespan was determined by monitoring the worms until they died. Statistical analysis was performed using the Kaplan-Meier version of the log-rank test.

Results:
Mianserin treatment resulted in a 12% increase in lifespan (P<0.05) of wild-type Bristol N2 worms but reduced lifespan by 6% in ANK3/unc-44 mutants, consistent with previous research. The addition of glucose to the diet reduced the lifespan of both strains of worms and abolished the lifespan-extension by mianserin.

Conclusion:
The addition of glucose to the diet of C. elegans abolishes the lifespan-extension effects of mianserin.
The Effect of Mianserin on Lifespan of Caenorhabditis elegans is Abolished by Glucose
Creators: name: Almotayri, Abdullah
name: Jency Thomas
name: Mihiri Munasinghe
name: Markandeya Jois
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: The antidepressant mianserin has been shown to extend the lifespan of Caenorhabditis elegans (C. elegans), a well-established model organism used in aging research. The extension of lifespan in C. elegans was shown to be dependent on increased expression of the scaffolding protein (ANK3/unc-44). In contrast, antidepressant use in humans is associated with an increased risk of death. The C. elegans in the laboratory are fed Escherichia coli (E. coli), a diet high in protein and low in carbohydrate, whereas a typical human diet is high in carbohydrates. We hypothesized that dietary carbohydrates might mitigate the lifespan-extension effect of mianserin. Objective: To investigate the effect of glucose added to the diet of C. elegans on the lifespan-extension effect of mianserin. Methods: Wild-type Bristol N2 and ANK3/unc-44 inactivating mutants were cultured on agar plates containing nematode growth medium and fed E. coli. Treatment groups included (C) control, (M50) 50 μM mianserin, (G) 73 mM glucose, and (M50G) 50 μM mianserin and 73 mM glucose. Lifespan was determined by monitoring the worms until they died. Statistical analysis was performed using the Kaplan-Meier version of the log-rank test. Results: Mianserin treatment resulted in a 12% increase in lifespan (P<0.05) of wild-type Bristol N2 worms but reduced lifespan by 6% in ANK3/unc-44 mutants, consistent with previous research. The addition of glucose to the diet reduced the lifespan of both strains of worms and abolished the lifespan-extension by mianserin. Conclusion: The addition of glucose to the diet of C. elegans abolishes the lifespan-extension effects of mianserin.
Response surface methodology and artificial neural network modeling for fluoranthene degradation using Mycobacterium litorale
Creators: name: Dushyant R Dudhagara
name: Rajpara, Rahul K
name: Jwalant K Bhatt
name: Dave, Bharti P
Publisher: name: F1000Research
Year: 2016

description: Present study aims to investigate fluoranthene degradation by Mycobacterium litorale using computation modeling i.e. response surface methodology (RSM) and artificial neural network (ANN). The effect of various operational parameters as CaCl2 (0.03-0.09 g L-1), KH2PO4 (0.3-0.8 g L-1) and NH4NO3 (0.3-0.8 g L-1) were investigated using two different computation modeling. RSM is the most preferred method for optimization of medium components to date. In last few years, the ANN method has developed as one of the most efficient methods for empirical modeling and optimization, especially for non-linear systems. This study represents the comparative analysis between RSM and ANN for their predictive, generalization capabilities, parametric effects and sensitivity analysis. Experimental data were evaluated by applying RSM integrated with a desirability function approach. In this study, one hidden layer along with the backpropagation algorithm was selected for the proposed ANN model. Consequently, the specific backpropagation algorithm and the number of hidden neurons were optimized. The RSM derived central composite design model, resulted in 51.21% degradation on 3rd day with R2 value 0.9882. The Non linear ANN model predicted 51.28% degradation with 0.9970 R2 value. The root means square error (RMSE) and mean absolute percentage error (MAPE) values were found to be 0.3234 and 0.5715. The results indicated that the ANN model was more precise, consistent and reproducible, compared to the RSM model, proving the superiority of ANN model over RSM model. The study thus opens new avenues for the development of such models for effective remediation strategies for PAHs impacted habitats.
Tablet-based apps for phonics and phonological awareness: Protocol for an evidence-based appraisal of content, quality and usability
Creators: name: Furlong, Lisa
name: Natanya Serry
name: Erickson, Shane
name: Morris, Meg
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background The use of mobile apps to manage and promote health is becoming increasingly popular. Mobile apps are gaining popularity particularly in educational and interventional settings owing to their perceived advantages including support for and engagement of individuals with reading difficulties. In the context of COVID-19, the need for technology-based tools has increased. For practitioners and educators who wish to use apps in their practice or recommend apps to individuals with reading difficulties, it is challenging to identify high-quality apps in app stores. Objective This protocol describes a systematic search, selection, and appraisal process for tablet apps targeting phonics knowledge and phonological awareness skills. This protocol aimed to (1) provide a systematic method for identifying tablet apps targeting phonics knowledge and phonological awareness skills in the Google Play Store and Apple’s App Store and (2) describe an evidence-based approach for quality appraisal of these apps by using structured tools. Methods This protocol describes an evidence-based method guided by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework to systematically search, select, and appraise apps targeting phonics knowledge and phonological awareness skills, present in Google Play and the App Store. We intend to perform a systematic and comprehensive search and a 2-step process for screening: (1) broad screening (app titles) and (2) narrow screening (marketing descriptions). Quality appraisal of the included apps will involve two structured appraisal tools: (1) the Mobile Application Rating Scale and (2) the Appraising Apps for Reading Checklist. Results This method will help determine the number of apps targeting phonics knowledge and phonological awareness, present on the Android and iOS platforms. The content, quality, and usability of these apps will be determined using structured appraisal tools. We have planned to conduct searches on Google Play and the App Store in January-March 2021; broad and focused screening, from April 2021; and data extraction and quality appraisal in October 2021. Conclusions This protocol provides a basis for locating and evaluating apps targeting phonics knowledge and phonological awareness skills. This protocol will support practitioners, educators, and families to make informed decisions when purchasing apps for instructional use. International Registered Report Identifier (IRRID) PRR1-10.2196/23921
Changes in prescribed treatments following parathyroidectomy for primary hyperparathyroidism in older adults
Creators: name: Purkiss, Shaun
name: Keegel, Tessa
name: Vally, Hassan
name: Wollersheim, Dennis
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © The Author(s). Aim and objective: Primary hyperparathyroidism (PHPT) is associated with multiple comorbidities and diverse symptomology that often require management with prescribed medications. Parathyroidectomy is an established treatment for PHPT but may also reduce the need for medications required to treat the associated conditions. We examined the changes in dispensed drugs given to a cohort of older adults with PHPT before and following parathyroidectomy. Materials and methods: A publicly available administrative Pharmaceutical and Medical Benefits Scheme database was used for this study. Participants aged >45 years undergoing parathyroidectomy for PHPT were identified by procedure codes for the period 2008 to 2014. Anatomic Therapeutic Chemical codes (ATC) assigned to drugs prescribed to individual participants, pre-and postoperatively, were used to define therapeutic groups and calculate cohort prevalences. Changes in dispensed medications following parathyroidectomy were assessed by the modulation of ATC class prevalence estimates of drugs prescribed using the Autoregressive Integrated Moving Averages (ARIMA) time-series methodology. Results: Six hundred and ten persons aged >45 years (M 72.1, SD 7.0) undergoing parathyroidectomy for PHPT were recruited. Preoperative dispensed treatment prevalences were highest for agents acting on the renin–angiotensin system (48%), dyslipidemia (45%), acid disorders (37%), antibiotics (31%), and analgesics (20%). Treatment prevalences for all ATC defined medications remained either unchanged or increased 3 years postoperatively. Polypharmacy following surgery also increased from an average 5.9 (SD = 4.0, range 0–23) prescribed medications for chronic conditions preoperatively to 7.0 (SD = 4.0) at 2 years (p < 0.001). Conclusion: The prevalence of ATC classified drugs prescribed and dispensed for chronic conditions in older adults with PHPT changed minimally following parathyroidectomy and polypharmacy of dispensed medications increased. Clinical significance: Parathyroidectomy performed in older persons for PHPT has a limited impact on the prevalence of dispensed drugs used to treat many of the associated chronic conditions. Mesh: Big data; Chronic conditions; Drug utilization; Hyperparathyroidism; Polypharmacy; Primary; Surgery.
title: Letter: Donald L. Wilkins to Hiram Davis, M.D., November 6, 1958
Creators: name: Wilkins, Donald L.
Publisher: name: George Mason University
Year: 2007
Subjects: subject: Mental institutions

description: Letter: 2 pgs, typescript signed, 11" x 8.5" (27.9 cm x 21.6 cm)
description: Letter from Daniel L. Wilkins to Hiram Davis, M.D., Director of the Bureau of Mental Hygiene, State Hospital Board, regarding the establishment of a mental health facility in Fairfax. C. Harrison Mann, Jr. Collection 21.17
title: Minnesota Disability Health Options: Expanding Coverage for Adults with Physical Disabilities
Creators: name: Palsbo, Susan E.
name: Beatty, Philip W.
name: Parker, Pamela
name: Duff, Chris
Publisher: name: Center for Health Care Strategies
Year: 2004
Subjects: subject: Disability
subject: Medicaid
subject: Care coordination
subject: MnDHO
subject: Capitation

description: Also available from www.chcs.org
description: Minnesota Disability Health Options (MnDHO), is a specialized managed health care program for working-age Medicaideligible individuals (with or without Medicare) with physical disabilities who reside in Minneapolis-St. Paul. MnDHO, a voluntary program, integrates delivery of all Medicaid and Medicare services except for prescription medications. Interviews and focus groups at the end of the first year show that enrollees’ quality of life is much better, with enrollees able to focus their attention on non-health related concerns.
Additional file 1 of Neutralizing antibody and T cell responses against SARS-CoV-2 variants of concern following ChAdOx-1 or BNT162b2 boosting in the elderly previously immunized with CoronaVac vaccine
Creators: name: Liwsrisakun, Chalerm
name: Pata, Supansa
name: Laopajon, Witida
name: Takheaw, Nuchjira
name: Chaiwong, Warawut
name: Inchai, Juthamas
name: Pothirat, Chaicharn
name: Bumroongkit, Chaiwat
name: Deesomchok, Athavudh
name: Theerakittikul, Theerakorn
name: Limsukon, Atikun
name: Tajarernmuang, Pattraporn
name: Niyatiwatchanchai, Nutchanok
name: Trongtrakul, Konlawij
name: Chuensirikulchai, Kantinan
name: Kasinrerk, Watchara
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Figure S1. Flow cytometry and gating strategy. PBMCs were stimulated with the SARS-CoV-2 peptide pool of spike proteins, and IL-17A, IFN-γ and FasL expression levels were determined by flow cytometry. The gating strategies are shown. (A) The size (FSC-A) and granularity (SSC-A) of PBMCs were plotted and gated as indicated. (B) The gated cells were represented in an SSC-H vs. SSC-A dot plot to eliminate doublets. (C) CD3 T cells were gated by plotting CD3 staining vs. SSC-A. (D) CD4 T cells and CD8 T cells were gated from CD3 T cells by plotting CD8 vs. CD4 staining. The CD4 T cells (E) and CD8 T cells (F) were plotted against CD4 or CD8 staining and IL-17A, IFN-γ or FasL expression. IFN-γ is shown as an example in this figure. The percentages of IL-17A-, IFN-γ- or FasL-producing cells were investigated. Figure S2. T-cell responses to wild-type spike peptide homology with the mutated regions in spike variants B.1.1.7, B.1.351 and B.1.617.2. PBMCs were stimulated with a pool of wild-type spike peptides showing homology to mutated regions in the spike proteins of (A) B.1.1.7 mutation; Alpha variants, (B) B.1.351 mutation; Beta variants, or (C) B.1.617.2 mutation; Delta variants. Immunofluorescence staining and flow cytometry were used to determine the frequency of CD4 or CD8 T cells expressing IL-17A, IFN-γ or FasL. Individual data points before (2CoVac) (N = 6) and 4 weeks after boosting with ChAdOx-1 (2CoVac + ChAd) (N = 10) or BNT162b2 (2CoVac + BNT) (N = 10) are shown. Lines represent the median with the interquartile range. The Mann–Whitney U test was used for comparison. ns indicates no significant difference (p > 0.05), * p ≤ 0.05, ** p ≤ 0.01, and*** P 0.05), and * represents p ≤ 0.05.
Identifying tobacco retailers in the absence of a licensing system: Lessons from australia
Creators: name: Baker, John
name: Masood, Mohd
name: Rahman, Muhammad
name: L Thornton
name: Begg, Stephen
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objectives: To estimate the proportion of retailers that sell tobacco in the absence of appropriate local government oversight, and to describe the characteristics by which they differ from those that can expect to receive such oversight. Methods: A database of listed tobacco retailers was obtained from a regional Victorian local government. Potential unlisted tobacco retailers were added using online searches, and attempts to visit all retailers were undertaken. GPS coordinates and sales type information of retailers that sold tobacco were recorded and attached to neighbourhood-level data on socioeconomic disadvantage and smoking prevalence using ArcMap. Logistic regression analyses, χ2 tests and t-tests were undertaken to explore differences in numbers of listed and unlisted retailers by business and neighbourhood-level characteristics. Results: Of 125 confirmed tobacco retailers, 43.2% were trading potentially without government oversight. Significant differences were found between listed and unlisted retailers by primary business type (p<0.001), and sales type (p<0.001) but not by the other characteristics. Conclusions: The database of tobacco retailers was inaccurate in two ways: (1) a number of listed retailers no longer operated or sold tobacco, and (2) 43.2% of businesses confirmed as selling tobacco were missing. As no form of licensing system exists in Victoria, it is difficult to identify the number of retailers operating, or to determine how many receive formal regulatory oversight. A positive licensing system is recommended to regulate the sale of tobacco and to generate a comprehensive database of retailers, similar to that which exists for food registration, gaming and liquor-licensed premises.