cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung
Creators: name: Lüdtke, Timo H.
name: Wojahn, Irina
name: Kleppa, Marc-Jens
name: Schierstaedt, Jasper
name: Christoffels, Vincent M.
name: Künzler, Patrick
name: Kispert, Andreas
Publisher: name: London : BioMed Central
Year: 2021
Subjects: subject: CBX3
subject: HDAC
subject: HMGB2
subject: Lung development
subject: NuRD
subject: PBX1
subject: Pulmonary mesenchyme
subject: Tbx2
subject: 610

description: Background: Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was traced to direct repression of the cell-cycle inhibitor genes Cdkn1a and Cdkn1b, as well as of genes encoding WNT antagonists, Frzb and Shisa3, to increase pro-proliferative WNT signaling. Despite these important molecular insights, we still lack knowledge of the DNA occupancy of TBX2 in the genome, and of the protein interaction partners involved in transcriptional repression of target genes. Methods: We used chromatin immunoprecipitation (ChIP)-sequencing and expression analyses to identify genomic DNA-binding sites and transcription units directly regulated by TBX2 in the developing lung. Moreover, we purified TBX2 containing protein complexes from embryonic lung tissue and identified potential interaction partners by subsequent liquid chromatography/mass spectrometry. The interaction with candidate proteins was validated by immunofluorescence, proximity ligation and individual co-immunoprecipitation analyses. Results: We identified Il33 and Ccn4 as additional direct target genes of TBX2 in the pulmonary mesenchyme. Analyzing TBX2 occupancy data unveiled the enrichment of five consensus sequences, three of which match T-box binding elements. The remaining two correspond to a high mobility group (HMG)-box and a homeobox consensus sequence motif. We found and validated binding of TBX2 to the HMG-box transcription factor HMGB2 and the homeobox transcription factor PBX1, to the heterochromatin protein CBX3, and to various members of the nucleosome remodeling and deacetylase (NuRD) chromatin remodeling complex including HDAC1, HDAC2 and CHD4. Conclusion: Our data suggest that TBX2 interacts with homeobox and HMG-box transcription factors as well as with the NuRD chromatin remodeling complex to repress transcription of anti-proliferative genes in the pulmonary mesenchyme.
電子メールによる依頼行動の展開から見る中間言語の発達―中国人日本語学習者と母語話者の相違を中心に―
Creators: name: 王冠亮
name: 史琨茹
Publisher: name: Zenodo
Year: 2018

description: (I-JAS)電子メールにおける依頼行動から中国人学習者の日本語使用傾向を検討し、その特徴を明らかにした。
Evolutionary population synthesis: the effect of binary systems
Creators: name: Mas-Hesse, J. M.
name: Cervino, M.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present in this contribution our set of multiwavelength synthesis models including the evolution of single and binary stars. The main results we have obtained can be summarized as follows: (a) massive close-binary systems will start to experience mass transfer episodes after the first 4 Myr of the starburst evolution; (b) as a result of these mass transfer processes, stars of relatively low initial mass can loose completely their envelope and become a WR. In this way, the formation of WR stars is extended over longer than 15 Myr, and does not stop at 6 Myr as predicted by models including only single stars; (c) WR stars can thus be coeval with red supergiants, which peak at around 10 Myr for solar metallicities; (d) the accretion of mass will originate relatively massive stars at ages for which they should have already disappeared; these stars, together with the WR stars formed in rather evolved clusters, increase the production of ionizing photons, so that the H$β$ equivalent width will not drop as rapidly as predicted by models considering only individual stars; and (e) the mass transfer to compact companions will produce an additional source of high-energy radiation in the form of high-mass X-ray binaries, not predicted either by standard synthesis models.
description: 8 pages, 3 figures. IAU Symp 193 (conference proceeding)
DECam Survey for Low-Mass Stars and Substellar Objects in the UCL and LCC Subgroups of the Sco-Cen OB Association (SCOCENSUS)
Creators: name: Moolekamp, Fred E.
name: Mamajek, Eric E.
name: James, David J.
name: Luhman, Kevin L.
name: Pecaut, Mark J.
name: Metchev, Stanmir A.
name: Bell, Cameron P. M.
name: Denbo, Sara R.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Using images taken with the Dark Energy Camera (DECam), the first extensive survey of low mass and substellar objects is made in the 15-20 Myr Upper Centaurus Lupus (UCL) and Lower Centaurus Crux (LCC) subgroups of the Scorpius Centaurus OB Association (Sco-Cen). Due to the size of our dataset (>2Tb) we developed an extensive open source set of python libraries to reduce our images, including astrometry, coaddition, and PSF photometry. Our survey consists of 29$\times$3 deg$^2$ fields in the UCL and LCC subgroups of Sco-Cen and the creation of a catalog with over 11 million point sources. We create a prioritized list of candidate for members in UCL and LCC, with 118 \emph{best} and another 348 \emph{good} candidates. We show that the luminosity and mass functions of our low mass and substellar candidates are consistent with measurements for the younger Upper Scorpius subgroup and estimates of a universal IMF, with spectral types ranging from M1 down to L1.
description: 26 pages, 27 figures
Sphinx caricae Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Sphingidae
Sphinx
Sphinx caricae

description: Sphinx caricae [spec. nov.]
S. alis integris: posticis supra luteis, abdomine cineteo: cingulis nigris. M. L. U.
Merian. surin. 64. f. 1. 2.
Habitat in Carica Americes.
Thorax lineis atris. Alae superiores fuscae venis atris undato-fasciatae.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 491, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
title: Karten, Kartographiegeschichte, Geschichtskarten
Creators: name: Crom, Wolfgang
name: Heinz, Markus
Publisher: name: Fachinformationsdienst für Kartographie und Geobasisdaten
Year: 2018
Subjects: subject: Kartografie
subject: Karte
subject: Atlas
subject: cartography
subject: map
subject: 520

description: Clio Guide: ein Handbuch zu digitalen Ressourcen für die Geisteswissenschaften, p. 1
Additional file 3: of A paratransgenic strategy to block transmission of Xylella fastidiosa from the glassy-winged sharpshooter Homalodisca vitripennis
Creators: name: Arinder Arora
name: Pesko, Kendra
name: Verรณnica Quintero-Hernรกndez
name: Lourival Possani
name: Miller, Thomas
name: Durvasula, Ravi
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Figure S3. Confirmation of secretion and accumulation of melittin conjugated to HlyA secretion signal by transformed P. agglomerans lines in spent media as well as within the sharpshooter gut. (a) Spent media were concentrated and were analyzed using an anti-melittin bleed via Western blot. Lane 1: melittin conjugated to HlyA secretion signal; lane 2: synthetic melittin; lane 3: ladder. (b) A sharpshooter homogenate was analyzed using an anti-melittin bleed. Lane 1: ladder; lane 2: sharpshooter fed on P. agglomerans expressing melittin conjugated to HlyA secretion signal; lane 3: sharpshooter fed on wild type P. agglomerans. Two glassy-winged sharpshooters were tested for the presence of melittin using an anti-melittin bleed and both were positive. (DOCX 157 kb)
Piper crocatum Ruiz & Pav. ameliorates wound healing through p53, E-cadherin and SOD1 pathways on wounded hyperglycemia fibroblasts
Creators: name: Setyawati, Andina
name: Wahyuningsih, Mae Sri Hartati
name: Nugrahaningsih, Dwi Aris Agung
name: Effendy, Christantie
name: Fneish, Firas
name: Fortwengel, Gerhard
Publisher: name: Amsterdam [u.a.] : Elsevier
Year: 2021
Subjects: subject: Diabetic wound healing
subject: E-cadherin
subject: Mechanism
subject: p53
subject: Piper crocatum Ruiz & Pav
subject: SOD1
subject: 570

description: Introduction: Piper crocatum Ruiz & Pav (P. crocatum) has been reported to accelerate the diabetic wound healing process empirically. Some studies showed the benefits of P. crocatum in treating various diseases but its mechanisms in diabetic wound healing have never been reported. In the present study we investigated the diabetic wound healing activity of the active fraction of P. crocatum on wounded hyperglycemia fibroblasts (wHFs). Methods: Bioassay-guided fractionation was performed to get the most active fraction. The selected active fraction was applied to wHFs within 72 h incubation. Mimicking a diabetic condition was done using basal glucose media containing an additional 17 mMol/L D-glucose. A wound was simulated via the scratch assay. The collagen deposition was measured using Picro-Sirius Red and wound closure was measured using scratch wound assay. Underlying mechanisms through p53, αSMA, SOD1 and E-cadherin were measured using western blotting. Results: We reported that FIV is the most active fraction of P. crocatum. We confirmed that FIV\(7.81 µg/ml, 15.62 µg/ml, 31.25 µg/ml, 62.5 µg/ml, and 125 µg/ml) induced the collagen deposition and wound closure of wHFs. Furthermore, FIV treatment (7.81 µg/ml, 15.62 µg/ml, 31.25 µg/ml) down-regulated the protein expression level of p53 and up-regulated the protein expression levels of αSMA, E-cadherin, and SOD1. Discussion/conclusions: Our findings suggest that ameliorating collagen deposition and wound closure through protein regulation of p53, αSMA, E-cadherin, and SOD1 are some of the mechanisms by which FIV of P. crocatum is involved in diabetic wound healing therapy.
Additional file 1: of Adherence to the International Committee of Medical Journal Editorsâ (ICMJE) prospective registration policy and implications for outcome integrity: a cross-sectional analysis of trials published in high-impact specialty society journals
Creators: name: Gopal, Anand
name: Wallach, Joshua
name: Jenerius Aminawung
name: Gonsalves, Gregg
name: Dal-RĂŠ, Rafael
name: Miller, Jennifer
name: Ross, Joseph
Publisher: name: figshare
Year: 2018
Subjects: Medicine
Developmental Biology
Science Policy

description: Study protocol. This file contains the original study protocol in addition to a listing of protocol amendments. (DOCX 156 kb)
Sphinx ello Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Sphingidae
Sphinx
Sphinx ello

description: Sphinx ello [spec. nov.]
S. alis integris: posticis rufis margine crassiore nigris, abdomine pallido cingulis atris. M. L. U.
Habitat in India.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 491, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Propagators of the Dirac fermions on spatially flat FLRW spacetimes
Creators: name: Cotaescu, Ion I.
Publisher: name: arXiv
Year: 2018
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The general formalism of the free Dirac fermions on spatially flat $(1+3)$-dimensional Friedmann-Lema\^ itre-Robertson-Walker (FLRW) spacetimes is developed in momentum representation. The mode expansions in terms of the fundamental spinors satisfying the charge conjugation and normalization conditions are used for deriving the structure of the anti-commutator matrix-functions and, implicitly, of the retarded, advanced, and Feynman fermion propagators. The principal result is that the new type of integral representation we proposed recently in the de Sitter case can be applied to the Dirac fermions in any spatially flat FLRW geometry. Moreover, the Dirac equation of the left-handed massless fermions can be analytically solved finding a general spinor solution and deriving the integral representations of the neutrino propagators. It is shown that in the Minkowski flat spacetime our new integral representation is up to a change of variable just like the usual Fourier representation of the fermion propagators. The form of the Feynman propagator of the massive fermions on a spatially flat FLRW spacetime with a scale factor of Milne-type is also outlined.
description: 27 pages, 2 figures. Matches the published version. Typos are corrected
Using machine learning methods to better understand the complexities of modern slavery
Creators: name: Lavelle-Hill, Rosa
name: Mazumder, Anjali
name: Goulding, James
name: Smith, Gavin
Publisher: name: Zenodo
Year: 2020
Subjects: Machine Learning
Modern Slavery
Rashomon Set
Sustainable Development Goals

description: Not only is the crime of modern slavery a hidden one, but global definitions also vary, as do cultural norms on issues such as child marriage, child labour and forced marriage. In this nuanced context, this research goes beyond the traditional regression analyses used in this space, to try to understand not just the linear predictive relationships, but also the non-linear effects, thresholds, interaction effects, and potential subgroups of countries. Consequently, this research, in the context of small data (N=70) and many potential (and correlated) predictors (107), utilises machine learning methods with the goal to better predict and explain countries' prevalence of MDS, with all its complexities. Data is collated and scraped from multiple open sources including the World Bank, Varieties of Democracy Project (Coppedge et al., 2015), The Woman Stats Project, and the Global Slavery Index, which includes a measure of slavery prevalence measured by the Gallup World Poll. Our methodology investigates the utility of theory driven feature selection and data driven feature compression, followed by the evaluation of different prediction models. The approach that gave the most accurate out of sample predictions used NMF to reduce the feature space, and a decision tree to predict MDS prevalence. Stability of the model over different random seeds was then assessed, and a Rashomon set (other reasonably accurate predictive models, which may contain a simpler more interpretable model) identified (Rudin, 2019). Within the Rashomon set, the models’ predictions and their strategies were analysed to identify: 1) whether or not the models gave diverging predictions, or whether predictions were similar enough that a simpler, more interpretable, model could be substituted in; and 2) similarities between the models that could be used to provide more stable insights.
Spherical Harmonic Analysis of the PSCz Galaxy Catalogue: Redshift distortions and the real-space power spectrum
Creators: name: Tadros, H.
name: Ballinger, W. E.
name: Taylor, A. N.
name: Heavens, A. F.
name: Efstathiou, G.
name: Saunders, W.
name: Frenk, C. S.
name: Keeble, O.
name: McMahon, R.
name: Maddox, S. J.
name: Oliver, S.
name: Rowan-Robinson, M.
name: White, W. J. Sutherland S. D. M.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We apply the formalism of spherical harmonic decomposition to the galaxy density field of the IRAS PSCz redshift survey. The PSCz redshift survey has almost all-sky coverage and includes IRAS galaxies to a flux limit of 0.6 Jy. Using maximum likelihood methods to examine (to first order) the distortion of the galaxy pattern due to redshift coordinates, we have measured the parameter β= Ω^{0.6}/b. We also simultaneously measure (a) the undistorted amplitude of perturbations in the galaxy distribution when a parameterised power spectrum is assumed, or (b) the shape and amplitude of the real-space power spectrum if the band-power in a set of passbands is measured in a step- wise fashion. These methods are extensively tested on a series of CDM, ΛCDM and MDM simulations and are found to be unbiased. We obtain consistent results for the subset of the PSCz catalogue with flux above 0.75 Jy but inclusion of galaxies to the formal flux limit of the catalogue gives variations which are larger than our internal errors. For the 0.75 Jy catalogue we find, in the case of a parameterised power spectrum, β=0.58\pm0.26 and the amplitude of the real space power measured at wavenumber k=0.1 h/Mpc is Δ_{0.1}=0.42 \pm 0.03. Freeing the shape of the power spectrum we find that β=0.47\pm 0.16 (conditional error), and Δ_{0.1}=0.47 \pm 0.03. The shape of the real-space power spectrum is consistent with a Γ= 0.2 CDM-like shape parameter, but does not strongly rule out a number of other models. Finally by combining our estimate of the amplitude of galaxy clustering and the distortion parameter we find the amplitude of mass fluctuations on a scale k=0.1 \hmpc is Δ_ρ= 0.24 Ω_0^{-0.6}$, with an uncertainty of 50%.
description: 24 pages (Latex), 12 postscript figures included, accepted for publication in MNRAS
Football players with hip dysplasia: The relationship between muscle strength, functional performance, self-reported sport and recreation, cartilage defects and sex. A cross-sectional study
Creators: name: O'Brien, Michael
name: Kemp, Joanne
name: Semciw, Adam
name: Mechlenburg, Inger
name: Jacobsen, Julie S
name: King, Matthew
name: Scholes, Mark
name: Lawrenson, Peter
name: Crossley, Kay
name: Agricola, Rintje
name: Souza, Richard B
name: Heerey, Joshua
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 4207
subject: Sports science and exercise
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 4201
subject: Allied health and rehabilitation science

description: No description supplied.
A multidisciplinary scientific investigation of the 1916 Hawthorn Mine Crater, Beaumont Hamel, Somme, Northern France
Creators: name: Wisniewski, K.D.
name: Doyle, P.
name: Hunter, R.J.S.
name: Pringle, J.K.
name: Stimpson, I.G.
name: Wright, D.
name: Squires, K.
name: Sutherland, Z.
name: Cassella, J.P.
name: Graham, F.C.
name: Ottey, P.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Physical Sciences not elsewhere classified
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: Hawthorn Crater is a prominent feature of the former Somme battlefield near Beaumont Hamel, Northern France. It resulted from the detonation of arguably the most famous of nine mines that the British had prepared below German lines on 1 July 1916, as part of the opening day of the Battle of the Somme. However, the crater has not been studied scientifically, as was in private land until recently taken over by the Hawthorn Crater Association. This paper documents three field seasons of multi-disciplinary site investigations. Methods included: remote sensing, drones, ground-based-LiDAR and surface surveys, geophysics and archaeological investigations. Magnetic anomalies were identified as: still-intact German fire pits, barbed wire and equipment, as the crater became the frontline after formation, and Allied shell craters. This study provided a rare opportunity to study a First World War mine crater, and highlighting modern science can assist detection and characterisation of significant archaeological sites.
Cleaning Interfaces in Layered Materials Heterostructures
Creators: name: Purdie, D. G.
name: Pugno, N. M.
name: Taniguchi, T.
name: Watanabe, K.
name: Ferrari, A. C.
name: Lombardo, A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Heterostructures formed by stacking layered materials require atomically clean interfaces. However, contaminants are usually trapped between the layers, aggregating into blisters. We report a process to remove such blisters, resulting in clean interfaces. We fabricate blister-free regions of graphene encapsulated in hexagonal boron nitride of$\sim$5000$μ$m$^{2}$, limited only by the size of the exfoliated flakes. These have mobilities up to$\sim$180000cm$^2$V$^{-1}$s$^{-1}$ at room temperature, and$\sim$1.8$\times$10$^6$cm$^2$V$^{-1}$s$^{-1}$ at 9K. We further demonstrate the effectiveness of our approach by cleaning heterostructures assembled using graphene intentionally exposed to polymers and solvents. After cleaning, these samples reach similar high mobilities. We also showcase the general applicability of our approach to layered materials by cleaning blisters in other heterostructures based on MoS$_{2}$. This demonstrates that exposure of graphene to processing-related contaminants is compatible with the realization of high mobility samples, paving the way to the development of fab-based processes for the integration of layered materials in (opto)-electronic devices.
Electron-Electron Interactions and the Hall-Insulator
Creators: name: Zheng, Lian
name: Fertig, H. A.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: Using the Kubo formula, we show explicitly that a non-interacting electron system can not behave like a Hall-insulator, {\it ie.,} a DC resistivity matrix $ρ_{xx}\rightarrow\infty$ and $ρ_{xy}=$finite in the zero temperature limit, as has been observed recently in experiment. For a strongly interacting electron system in a magnetic field, we illustrate, by constructing a specific form of correlations between mobile and localized electrons, that the Hall resistivity can approximately equal to its classical value. A Hall-insulator is realized in this model when the density of mobile electrons becomes vanishingly small. It is shown that in non-interacting electron systems, the zero-temperature frequency-dependent conductacnce generally does not give the DC conductance.
description: 11 pages, RevTeX3.0
IN03012 Vessagiri Rock B Cave 4 Inscription
Creators: name: Wickremasinghe, Don Martino de Zilva
Publisher: name: Zenodo
Year: 2019
Subjects: IN03012
Epigraphia Zeylanica
Vessagiri

description: IN03012 Vessagiri Rock B Cave 4 Inscription - Transcript and Translation Source: Wickremasinghe, Don Martino de Zilva. (1904-12). ‘No. 2. Vessagiri Inscriptions,’ Epigraphia Zeylanica 1, pp. 10-39.
Additional file 1: of Three operational models for ambidexterity in large corporations
Creators: name: Alänge, Sverker
name: Steiber, Annika
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Translation of the abstract into Arabic. (PDF 58 kb)
Sphinx labruscae Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Sphingidae
Sphinx
Sphinx labruscae

description: Sphinx labruscae [spec. nov.]
S. alis subfuscis: posticis subtus puncto albo, abdomine lateribus punctis V albis. M. L. U.
Merian. sur. t. 34.
Habitat in Vite Americes.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 491, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Cart. 192 (11 H 77), 295 folios, f. 0190r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0190r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0190r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Solenoidal Improvements for the JF12 Galactic Magnetic Field Model
Creators: name: Kleimann, Jens
name: Schorlepp, Timo
name: Merten, Lukas
name: Tjus, Julia Becker
Publisher: name: arXiv
Year: 2018
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The popular JF12 analytic model by Jansson & Farrar provides a quantitative description of the Galaxy's large-scale magnetic field, which is widely used in various astrophysical applications. However, both the poloidal X-type component and the spiral disk component of JF12 exhibit regions in which the magnetic divergence constraint is violated. We first propose a cure for this problem, resulting in a truly solenoidal large-scale spiral field. Second, the otherwise straight field lines of the X-type component exhibit kinks in the Galactic plane that, in addition to implying the presence of a singular current sheet, may pose difficulties for e.g., numerical tracing of cosmic-ray particles. We propose and discuss two possible strategies to mitigate this problem. Although all corrections are kept as minimal as possible, the extended set of model parameters will have to be carefully readjusted in order to fully restore the agreement to observational data that the unmodified JF12 field is based on. Furthermore, the performance of our improved version of the field model is quantitatively assessed by test simulations using the CRPropa Galactic cosmic-ray propagation code.
description: 12 pages, 6 figures
Hard X-ray-to-radio energy distributions in starburst galaxies
Creators: name: Cervino, M.
name: Mas-Hesse, J. M.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present in this contribution the predictions on the multiwavelength spectral energy distribution of our evolutionary population synthesis models including single and binary stellar systems. The high energy computations include the emission associated to X-ray binaries and supernovae remnants, as well as the mechanical energy released into the interstellar medium, which can be partially reprocessed into thermal X-rays. With these components we compute the spectral energy distribution of starburst galaxies from X-ray to radio ranges, and analyze finally the effects of the high energy emission on the H and He ionizing continuum.
description: 2 pages, 2 figures, IAU Symp 193 (conference proceeding)
Critical Exponents for Branching Annihilating Random Walks with an Even Number of Offspring
Creators: name: Jensen, Iwan
Publisher: name: arXiv
Year: 1994
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: Recently, Takayasu and Tretyakov [Phys. Rev. Lett. {\bf 68}, 3060 (1992)], studied branching annihilating random walks (BAW) with $n=1$-5 offspring. These models exhibit a continuous phase transition to an absorbing state. For odd $n$ the models belong to the universality class of directed percolation. For even $n$ the particle number is conserved modulo 2 and the critical behavior is not compatible with directed percolation. In this article I study the BAW with $n=4$ using time-dependent simulations and finite-size scaling obtaining precise estimates for various critical exponents. The results are consistent with the conjecture: $β/\nuh = {1/2}$, $\nuv/\nuh = {7/4}$, $γ= 0$, $δ= {2/7}$, $η= 0$, $z = {8/7}$, and $δ_{h} = {9/2}$.
description: 18 pages (+16 Fig.), LaTeX
Self-assembled nanoparticles based on block-copolymers of poly(2-deoxy-2-methacrylamido-d-glucose)/poly(n-vinyl succinamic acid) with poly(o-cholesteryl methacrylate) for delivery of hydrophobic drugs
Creators: name: Levit, Mariia
name: Vdovchenko, Alena
name: Dzhuzha, Apollinariia
name: Zashikhina, Natalia
name: Katernyuk, Elena
name: Gostev, Alexey
name: Sivtsov, Eugene
name: Lavrentieva, Antonina
name: Tennikova, Tatiana
name: Korzhikova-Vlakh, Evgenia
Publisher: name: Basel : Molecular Diversity Preservation International
Year: 2021
Subjects: subject: Amphiphilic copolymers
subject: Bio-inspired copolymers
subject: Block-copolymers
subject: Controlled radical polymerization
subject: Drug delivery systems
subject: Paclitaxel delivery
subject: Polymer nanoparticles
subject: 570
subject: 540

description: The self-assembly of amphiphilic block-copolymers is a convenient way to obtain soft nanomaterials of different morphology and scale. In turn, the use of a biomimetic approach makes it possible to synthesize polymers with fragments similar to natural macromolecules but more resistant to biodegradation. In this study, we synthesized the novel bio-inspired amphiphilic block-copolymers consisting of poly(N-methacrylamido-D-glucose) or poly(N-vinyl succinamic acid) as a hydrophilic fragment and poly(O-cholesteryl methacrylate) as a hydrophobic fragment. Block-copolymers were synthesized by radical addition–fragmentation chain-transfer (RAFT) polymerization using dithiobenzoate or trithiocarbonate chain-transfer agent depending on the first monomer, further forming the hydrophilic block. Both homopolymers and copolymers were characterized by1 H NMR and Fourier transform infrared spectroscopy, as well as thermogravimetric analysis. The obtained copolymers had low dispersity (1.05–1.37) and molecular weights in the range of ~13,000–32,000. The amphiphilic copolymers demonstrated enhanced thermal stability in comparison with hydrophilic precursors. According to dynamic light scattering and nanoparticle tracking analysis, the obtained amphiphilic copolymers were able to self-assemble in aqueous media into nanoparticles with a hydrodynamic diameter of approximately 200 nm. An investigation of nanoparticles by transmission electron microscopy revealed their spherical shape. The obtained nanoparticles did not demonstrate cytotoxicity against human embryonic kidney (HEK293) and bronchial epithelial (BEAS-2B) cells, and they were characterized by a low uptake by macrophages in vitro. Paclitaxel loaded into the developed polymer nanoparticles retained biological activity against lung adenocarcinoma epithelial cells (A549).
ROSAT HRI Monitoring of Extreme X-ray Variability in the Narrow-Line Quasar PHL 1092
Creators: name: Brandt, W. N.
name: Boller, Th.
name: Fabian, A. C.
name: Ruszkowski, M.
Publisher: name: arXiv
Year: 1999
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report results from an 18-day ROSAT HRI monitoring campaign on the ultrasoft Narrow-Line Seyfert 1 (NLS1) class quasar PHL 1092. This luminous, radio-quiet quasar showed strong X-ray variability in a short ROSAT PSPC observation, and ROSAT HRI monitoring of the similar object IRAS 13224-3809 revealed extreme variability on intermediate timescales. We wanted to determine whether remarkable X-ray variability persistently occurs in PHL 1092, and we also wanted to search for outstanding variability events that constrain emission processes. Given the large luminosity of PHL 1092 (about 5x10^{45} erg/s in the HRI band), we detect extremely rapid and large-amplitude X-ray variability throughout our monitoring. The maximum observed variability amplitude is a factor of about 14, and in the most rapid variability event the HRI count rate increases by a factor of about 3.8 in a rest-frame time interval of < 3580 s. The most rapid event has a rate change of luminosity of > 1.3x10^{42} erg/s^2, making it the most extreme such event we are aware of from a radio-quiet quasar. Standard `radiative efficiency limit' arguments imply a radiative efficiency larger than can be achieved by accretion onto a Kerr black hole rotating at the maximum plausible rate, although we point out that such arguments depend upon the geometry of initial radiation release. Relativistic motions of the X-ray source are probably causing the radiative efficiency limit to break down; such relativistic motions have also been inferred in the similar NLS1-class quasar PKS 0558--504.
description: 6 pages, MNRAS in press, also available from http://www.astro.psu.edu/users/niel/papers/papers.html
Interfaces and Lower Critical Dimension in a Spin Glass Model
Creators: name: Franz, S.
name: Parisi, G.
name: Virasoro, M. A.
Publisher: name: arXiv
Year: 1994
Subjects: subject: Condensed Matter (cond-mat)
subject: FOS: Physical sciences

description: In this paper we try to estimate the lower critical dimension for replica symmetry breaking in spin glasses through the calculation of the additional free-energy required to create a domain wall between two different phases. This mechanism alone would say that replica symmetry would be restored at the lower critical dimension $D_c =2.5$.
description: 14 pages, LaTeX, NORDITA preprint 94/21
Design and characterization of a melt electrostatic precipitator for advanced drug formulations
Creators: name: Justen, Anna
name: Weltersbach, Alina Faye
name: Schaldach, Gerhard
name: Thommes, Markus
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: Electrostatic precipitation
subject: Wall film
subject: Thermophoresis
subject: Solid dispersion
subject: Drug dissolution
subject: 660
subject: Elektroentstaubung
subject: Thermodiffusion
subject: Feststoff
subject: Dispersion
subject: Arzneimittel
subject: Formulierung

description: Electrostatic precipitators (ESP) are especially known for the efficient separation of micron and submicron particles from aerosols. Wet electrostatic precipitators are particularly suitable for highly resistive materials. Using these, particles can be directly transferred into a liquid for further processing or safer handling, which is advantageous for either hazardous or valuable materials. In this work, a wet ESP, which enables the separation of highly resistive particles into a heated liquid, was designed and investigated. To do this, spray-dried drug particles were embedded in a molten sugar alcohol to enhance the drug dissolution rate. After cooling, the solidified product showed advantageous properties such as a high drug dissolution rate and easy handling for further processing. For the design of the wet ESP, different discharge electrode configurations were tested. A wall film served as the collection electrode, which was generated by a specially designed distributer die. A laminar flow regime was achieved with a homogeneous film serving as the collection electrode, which is particularly important for a high separation efficiency. A prototype was designed and constructed in this respect. The particle separation into hot liquids or onto hot surfaces is challenging due to thermal effects in ESPs. The influence of thermophoresis and drag force on the particle transport was investigated, and optimum operation parameters were found for the present ESP. A broad field of applications can be covered with the presented device, where particles are embedded in even hot liquids to form liquid suspensions or, as it is presented here, solid dispersions. The dissolution of the drug-containing solid dispersion was studied in vitro. A remarkably faster drug dissolution was observed from the solid dispersion, as compared to a powder mixture of the drug and xylitol.
description: Processes;12(1)
Additional file 2: of A paratransgenic strategy to block transmission of Xylella fastidiosa from the glassy-winged sharpshooter Homalodisca vitripennis
Creators: name: Arinder Arora
name: Pesko, Kendra
name: Verรณnica Quintero-Hernรกndez
name: Lourival Possani
name: Miller, Thomas
name: Durvasula, Ravi
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Figure S2. (a) Assembly and working mechanism of Escherichia coli hemolysin secretion system. HlyB and HlyD form pores in the internal membrane of Gram negative bacteria. These pores join pores formed by TolC in the outer membrane and provide a passage to proteins with the HlyA secretion signal. (b) Depiction of cloning of AMP genes in pEHLYA2-SD plasmid. (DOCX 137 kb)
Additional file 1: of IL-6-mediated cross-talk between human preadipocytes and ductal carcinoma in situ in breast cancer progression
Creators: name: Kim, Hoe Suk
name: Minji Jung
name: Choi, Sul Ki
name: Jisu Woo
name: Piao, Yin Ji
name: Hwang, Eun Hye
name: Hyelim Kim
name: Kim, Seung Ja
name: Moon, Woo Kyung
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Plant Biology
subject: 60506 Virology

description: Supplementary FiguresÂ and Table. (DOCX 6073 kb)
Realizability Interpretation and Normalization of Typed Call-by-Need $$λ$$-calculus With Control
Creators: name: Miquey, Étienne
name: Herbelin, Hugo
Publisher: name: arXiv
Year: 2018
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences

description: We define a variant of realizability where realizers are pairs of a term and a substitution. This variant allows us to prove the normalization of a simply-typed call-by-need $$λ$-$calculus with control due to Ariola et al. Indeed, in such call-by-need calculus, substitutions have to be delayed until knowing if an argument is really needed. In a second step, we extend the proof to a call-by-need $$λ$$-calculus equipped with a type system equivalent to classical second-order predicate logic, representing one step towards proving the normalization of the call-by-need classical second-order arithmetic introduced by the second author to provide a proof-as-program interpretation of the axiom of dependent choice.
MULocDeep: A deep-learning framework for protein subcellular and suborganellar localization prediction with residue-level interpretation
Creators: name: Jiang, Yuexu
name: Wang, Duolin
name: Yao, Yifu
name: Eubel, Holger
name: Künzler, Patrick
name: Møller, Ian Max
name: Xu, Dong
Publisher: name: Gotenburg : Research Network of Computational and Structural Biotechnology (RNCSB)
Year: 2021
Subjects: subject: Deep learning
subject: Experimental benchmark datasets
subject: Mechanism study
subject: Protein localization
subject: Web server
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: Prediction of protein localization plays an important role in understanding protein function and mechanisms. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple localizations of a protein at both subcellular and suborganellar levels. We collected a dataset with 44 suborganellar localization annotations in 10 major subcellular compartments—the most comprehensive suborganelle localization dataset to date. We also experimentally generated an independent dataset of mitochondrial proteins in Arabidopsis thaliana cell cultures, Solanum tuberosum tubers, and Vicia faba roots and made this dataset publicly available. Evaluations using the above datasets show that overall, MULocDeep outperforms other major methods at both subcellular and suborganellar levels. Furthermore, MULocDeep assesses each amino acid's contribution to localization, which provides insights into the mechanism of protein sorting and localization motifs. A web server can be accessed at http://mu-loc.org.
Two-Color Grating Magneto-Optical Trap for Narrow-Line Laser Cooling
Creators: name: Bondza, S.
name: Lisdat, C.
name: Kroker, S.
name: Leopold, T.
Publisher: name: College Park, Md. [u.a.] : American Physical Society
Year: 2022
Subjects: subject: single-laser
subject: diffraction
subject: atoms
subject: beam
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: We demonstrate the two-color cooling and trapping of alkaline-earth atoms in a grating magneto-optical trap (GMOT). The trap is formed by a single incident laser beam together with four secondary beams that are generated via diffraction from a nanostructured wafer. A grating structure for a GMOT operating with strontium atoms is optimized and fabricated. We trap 10688Sr atoms on the 1S0→1P1 transition at 461nm and transfer 25% of these atoms to the second cooling stage on the narrower 1S0→3P1 intercombination transition at 689nm, preparing a sample of 2.5×105 atoms at 5μK. These results demonstrate the applicability of the GMOT technology in conjunction with two widely differing wavelengths and enable the continued miniaturization of alkaline-earth-based quantum technologies like optical atomic clocks.
Airy Function and 4d Quantum Gravity
Creators: name: Caputa, Pawel
name: Hirano, Shinji
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We study four-dimensional quantum gravity with negative cosmological constant in the minisuperspace approximation and compute the partition function for the $S^3$ boundary geometry. In this approximation scheme the path integrals become dominated by a class of asymptotically AdS "microstate geometries." Despite the fact that the theory is pure Einstein gravity without supersymmetry, the result precisely reproduces, up to higher curvature corrections, the Airy function in the $S^3$ partition function of the maximally supersymmetric Chern-Simons-matter (CSM) theory which sums up all perturbative $1/N$ corrections. We also show that this can be interpreted as a concrete realization of the idea that the CFT partition function is a solution to the Wheeler-DeWitt equation as advocated in the holographic renormalization group. Furthermore, the agreement persists upon the inclusion of a string probe and it reproduces the Airy function in the vev of half-BPS Wilson loops in the CSM theory. These results may suggest that the supergravity path integrals localize to the minisuperspace in certain cases and the use of the minisuperspace approximation in AdS/CFT may be a viable approach to study $1/N$ corrections to large $N$ CFTs.
description: 17 pages
title: ADCO, Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Cart. 176 (11 H 8), f. 0033
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: cartulaire
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi

description: Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 176 (11 H 8), f. 0033, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Privilèges de l'Ordre de Cîteaux en matière de succession (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 176 (11 H 8), f. 0033, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Optimally Mapping Large-Scale Structures with Luminous Sources
Creators: name: Cheng, Yun-Ting
name: de Putter, Roland
name: Chang, Tzu-Ching
name: Dore, Olivier
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Intensity mapping has emerged as a promising tool to probe the three-dimensional structure of the universe. The traditional approach of galaxy redshift surveys is based on individual galaxy detection, typically performed by thresholding and digitizing large-scale intensity maps. By contrast, intensity mapping uses the integrated emission from all sources in a 3D pixel (or voxel) as an analog tracer of large-scale structure. In this work, we develop a formalism to quantify the performance of both approaches when measuring large-scale structures. We compute the Fisher information of an arbitrary observable, derive the optimal estimator, and study its performance as a function of source luminosity function, survey resolution, instrument sensitivity, and other survey parameters. We identify regimes where each approach is advantageous and discuss optimal strategies for different scenarios. To determine the best strategy for any given survey, we develop a metric that is easy to compute from the source luminosity function and the survey sensitivity, and we demonstrate the application with several planned intensity mapping surveys.
description: 21 pages, 15 figures, accepted by ApJ
Sphinx ficus Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Sphingidae
Sphinx
Sphinx ficus

description: Sphinx ficus [spec. nov.]
S. alis fusco nebulosis: posticis angulo ani albis. M. L. U.
Merian. sur. t. 33.
Habitat in Ficu Americes.
Alae superiores in medio puncto fusco; inferiores supra fasciis 2 fuscis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 491, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206