cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cecropia hololeuca: A new source of compounds with potential anti-inflammatory action
Creators: name: Machado, Emanuelle G.
name: Cardoso, Oswaldo
name: Lima, Nerilson M.
name: Carvalho, Paloma E.
name: Barbosa, Alice D.
name: Sobrinho, Guilherme F. S.
name: Duarte, Jennifer F.
name: Coelho, Laryssa R.
name: Soares, Pietra P. C.
name: Orneles, Ayane G.
name: Santos, Ana Carolina B.
name: Santos, Kamila B.
name: Castro, Sandra B. R.
name: de Oliveira, Marcone A. L.
name: Carli, Alessandra P.
name: Alves, Caio Cesar Souza
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Our objective is to investigate the phytochemical components, antioxidant capacity and in vitro and in vivo anti-inflammatory action from Cecropia hololeuca bark aqueous extract (AECh). The chemical characterization of AECh was performed through CE-UV, FTIR and NMR Spectroscopy. In vitro assays were performed with the AECh on murine macrophages J774A.1 cells in order to analyse cell viability, NO, TNF-α and IL-1β productions and the in vivo anti-inflammatory potential in acute carrageenan paw oedema in mice. The AECh showed a decrease in the production of NO, TNF-α and IL-1β, without altering the cell viability and reduction of the paw thickness in the 2nd, 3rd and 4th hour. The extract presented 72% free radical scavenging, 0.60% flavonoid content and showed the presence of gallic acid, caffeic acid and catechin as major constituents. The C. hololeuca bark extract showed important antioxidant and anti-inflammatory activity, emphasizing the industrial and pharmacological potential of this plant.
Generalized Hermite-Gauss decomposition of the two-photon state produced by spontaneous parametric down-conversion
Creators: name: Walborn, S. P.
name: Pimentel, A. H.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We provide a general decomposition of the two-photon state produced by spontaneous parametric down-conversion in Hermite-Gaussian modes, in the case that the pump beam is described by a Hermite-Gaussian beam of any order. We show that the spatial correlations depend explicitly on the order of the pump beam, as well as other experimental parameters. We use the decomposition to demonstrate a few interesting cases. Our results are applicable to the engineering of two-photon spatial entanglement, in particular for non-Gaussian states.
description: 14 page draft, 5 figures
Paeoniflorin benzoates: synthesis and influence on learning and memory of aged rats in the passive avoidance task
Creators: name: Baltina, Lidia
name: Sapozhnikova, Tatyana
name: Makara, Nina
name: Gabdrakhmanova, Svetlana
name: Baltina, Lia
name: Kondratenko, Rimma
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Paeoniflorin per-O-benzoates with the preserved pinane structure 2 and rearranged aglycone 3, containing C4 = O function, were obtained and their influence on learning and memory of aged rats was studied in the passive avoidance task. It was found that the chemical modification of paeoniflorin affected the cognitive functions of aged rats. The introduction of C4 = O function into the pinane part of benzoate 3 led to the improvement in learning process and preservation of the memory trace in aged rats as compared to the natural glycoside. This compound can be considered as the promising for further studies on in vivo models of disorders characteristic for Alzheimer’s disease.
Radio and gamma-ray follow-up of the exceptionally high activity state of PKS 1510-089 in 2011
Creators: name: Orienti, M.
name: Koyama, S.
name: D'Ammando, F.
name: Giroletti, M.
name: Kino, M.
name: Nagai, H.
name: Venturi, T.
name: Dallacasa, D.
name: Giovannini, G.
name: Angelakis, E.
name: Fuhrmann, L.
name: Hovatta, T.
name: Max-Moerbeck, W.
name: Schinzel, F. K.
name: Akiyama, K.
name: Hada, K.
name: Honma, M.
name: Niinuma, K.
name: Gasparrini, D.
name: Krichbaum, T. P.
name: Nestoras, I.
name: Readhead, A. C. S.
name: Richards, J. L.
name: Riquelme, D.
name: Sievers, A.
name: Ungerechts, H.
name: Zensus, J. A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the radio and gamma-ray variability of the flat spectrum radio quasar PKS 1510-089 in the time range between 2010 November and 2012 January. In this period the source showed an intense activity, with two major gamma-ray flares detected in 2011 July and October. During the latter episode both the gamma-ray and the radio flux density reached their historical peak. Multiwavelength analysis shows a rotation of about 380 deg of the optical polarization angle close in time with the rapid and strong gamma-ray flare in 2011 July. An enhancement of the optical emission and an increase of the fractional polarization both in the optical and in radio bands is observed about three weeks later, close in time with another gamma-ray outburst. On the other hand, after 2011 September a huge radio outburst has been detected, first in the millimeter regime followed with some time delay at centimeter down to decimeter wavelengths. This radio flare is characterized by a rising and a decaying stage, in agreement with the formation of a shock and its evolution, as a consequence of expansion and radiative cooling. If the gamma-ray flare observed in 2011 October is related to this radio outburst, then this strongly indicates that the region responsible for the gamma-ray variability is not within the broad line, but a few parsecs downstream along the jet.
description: 14 pages, 12 figures, accepted for publication in MNRAS
title: CISCOS Training Package
title: CISCOS-Schulungsmaterial
titleType: AlternativeTitle
Creators: name: (:Unkn) Unknown
Publisher: name: Universitätsbibliothek Siegen
Year: 2020
Subjects: subject: 360 Soziale Probleme, Sozialdienste, Versicherungen
subject: Behinderung
subject: Sozialarbeit
subject: Gemeinwesenarbeit
subject: Kommunale Planung
subject: Lehrmittel
subject: Teilhabe

description: "Connecting Inclusive Social Planning, Community Development and Service Provision for Persons with Disabilities" (CISCOS) resulted in a comprehensive study sourse connecting inclusive social planning, community development and inclusive service provision for persons with disabilities, adapted to both academic and non-academic settings, tailored to the needs of the service provision sector. The main aim of CISCOS is a mixed learning group of students and practitioners in self-advocacy organizations, institutions and services as well as local administrations. This model offers participants the opportunity to gain new learning experiences through exchange with other actors. The CISCOS training package consists of five parts. These are a) an introduction, b) a guide for trainers, c) a course manual, d) a course workbook and e) a toolkit for collaborative planning and development processes. CISCOS was co-funded by the Erasmus+ Programme of the European Union. The European Commission‘s support for the production of this publication does not constitute an endorsement of the contents, which reflect the views only of the authors, and the Commission cannot be held responsible for any use which may be made of the information contained therein.
description: Im Rahmen des Projekts „Connecting Inclusive Social Planning, Community Development and Service Provision for Persons with Disabilities“ (CISCOS) entwickelten die Projektpartner ein Fortbildungsprogramm, das inklusive Sozialplanung, Gemeinwesenentwicklung sowie inklusive Dienstleistungserbringung für Menschen mit Behinderungen verbindet. Der Kurs wurde auf die Anforderungen von Hochschulen sowie von Einrichtungen der Erwachsenenbildung und von Einrichtungen und Diensten der Hilfen für Menschen mit Behinderungen hin entwickelt. Zentrales Anliegen ist dabei eine gemischte Lerngruppe aus Studierenden sowie Praktiker*innen in Selbstvertretungsorganisationen, Einrichtungen und Diensten sowie kommunalen Verwaltungen. Dieses Modell bietet den Teilnehmer*innen die Möglichkeit, im Austausch mit anderen Akteuren neue Lernerfahrungen machen zu können. Das CISCOS-Trainingspaket besteht aus fünf Teilen. Diese sind a) eine Einführung, b) ein Leitfaden für Trainer*innen, c) ein Kurshandbuch, d) ein Arbeitsbuch und e) ein Methodenhandbuch für partizipative Planungs- und Entwicklungsprozesse. CISCOS wurde durch das Erasmus+ Programm der Europäischen Union kofinanziert. Die Unterstützung der Europäischen Kommission für die Erstellung dieser Veröffentlichung stellt keine Billigung des Inhalts dar, welcher nur die Ansichten der Verfasser wiedergibt, und die Kommission kann nicht für eine etwaige Verwendung der darin enthaltenen Informationen haftbar gemacht werden.
Additional file 1 of The relationship between high-density lipoprotein cholesterol (HDL-C) and glycosylated hemoglobin in diabetic patients aged 20 or above: a cross-sectional study
Creators: name: Huang, Rui
name: Yan, Li
name: Lei, Yuhua
Publisher: name: figshare
Year: 2021
Subjects: Biochemistry
Medicine
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Virology
Computational Biology

description: Additional file 1.
Additional file 1 of ICOR: improving codon optimization with recurrent neural networks
Creators: name: Jain, Rishab
name: Jain, Aditya
name: Mauro, Elizabeth
name: LeShane, Kevin
name: Densmore, Douglas
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. S1 Appendix comparison of approaches and results.
Four-nucleon alpha-type correlations and proton-neutron pairing away of N=Z line
Creators: name: Sandulescu, N.
name: Negrea, D.
name: Johnson, C. W.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the competition between alpha-type and conventional pair condensation in the ground state of nuclei with neutrons and protons interacting via a charge-independent pairing interaction. The ground state is described by a product of two condensates, one of alpha-like quartets and the other one of pairs in excess relative to the isotope with N=Z. It is shown that this ansatz for the ground state gives very accurate pairing correlation energies for nuclei with the valence nucleons above the closed cores 16O, 40Ca and 100Sn. These results indicate that alpha-type correlations are important not only for the self-conjugate nuclei but also for nuclei away of N=Z line. In the latter case alpha-like quartets coexist with the collective Cooper pairs formed by the nucleons in excess.
description: 10 pages, 4 tables
Self-force via $m$-mode regularization and 2+1D evolution: III. Gravitational field on Schwarzschild spacetime
Creators: name: Dolan, Sam R.
name: Barack, Leor
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: This is the third in a series of papers aimed at developing a practical time-domain method for self-force calculations in Kerr spacetime. The key elements of the method are (i) removal of a singular part of the perturbation field with a suitable analytic "puncture", (ii) decomposition of the perturbation equations in azimuthal ($m$-)modes, taking advantage of the axial symmetry of the Kerr background, (iii) numerical evolution of the individual $m$-modes in 2+1-dimensions with a finite difference scheme, and (iv) reconstruction of the local self-force from the mode sum. Here we report a first implementation of the method to compute the gravitational self-force. We work in the Lorenz gauge, solving directly for the metric perturbation in 2+1-dimensions. The modes $m=0,1$ contain nonradiative pieces, whose time-domain evolution is hampered by certain gauge instabilities. We study this problem in detail and propose ways around it. In the current work we use the Schwarzschild geometry as a platform for development; in a forthcoming paper---the fourth in the series---we apply our method to the gravitational self-force in Kerr geometry.
description: 56 pages, 17 figures
Detection of Small-Scale Granular Structures in the Quiet Sun with the New Solar Telescope
Creators: name: Abramenko, Valentyna
name: Yurchyshyn, Vasyl
name: Goode, Philip
name: Kitiashvili, Irina
name: Kosovichev, Alexander
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Results of a statistical analysis of solar granulation are presented. A data set of 36 images of a quiet Sun area on the solar disk center was used. The data were obtained with the 1.6 m clear aperture New Solar Telescope (NST) at Big Bear Solar Observatory (BBSO) and with a broad-band filter centered at the TiO (705.7 nm) spectral line. The very high spatial resolution of the data (diffraction limit of 77 km and pixel scale of 0.$"$0375) augmented by the very high image contrast (15.5$\pm$0.6%) allowed us to detect for the first time a distinct subpopulation of mini-granular structures. These structures are dominant on spatial scales below 600 km. Their size is distributed as a power law with an index of -1.8 (which is close to the Kolmogorov's -5/3 law) and no predominant scale. The regular granules display a Gaussian (normal) size distribution with a mean diameter of 1050 km. Mini-granular structures contribute significantly to the total granular area. They are predominantly confined to the wide dark lanes between regular granules and often form chains and clusters, but different from magnetic bright points. A multi-fractality test reveals that the structures smaller than 600 km represent a multi-fractal, whereas on larger scales the granulation pattern shows no multi-fractality and can be considered as a Gaussian random field. The origin, properties and role of the newly discovered population of mini-granular structures in the solar magneto-convection are yet to be explored.
description: 13 pages, 5 figures
Inhibition of nitric oxide production by clerodane diterpenoids from leaves and stems of Croton poomae Esser
Creators: name: Somteds, Apisara
name: Tantapakul, Cholpisut
name: Kanokmedhakul, Kwanjai
name: Laphookhieo, Surat
name: Phukhatmuen, Piyaporn
name: Kanokmedhakul, Somdej
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Chromatographic separation of crude extracts from the leaves and stems of Croton poomae Esser led to the isolation of two new clerodane diterpenes crotonolide K (1) and furocrotinsulolide A acetate (2) and six known clerodane diterpenes (3–8), together with twelve known compounds (9–20). Their structures were established from spectroscopic analysis. The clerodane diterpenoids 1–8 were evaluated for inhibition of nitric oxide (NO) production in LPS-activated RAW 264.7 macrophages. Compounds 1, 2, 5, 7 and 8 showed potent inhibitory effects, with IC50 values ranging from 32.19 to 48.85 μM, which is better than both the standard drugs indomethacin (154.5 μM) and dexamethasone (56.28 μM).
Re-Examining Embodied SO2 and CO2 Emissions in China
Creators: name: Huang, Rui
name: Hubacek, Klaus
name: Feng, Kuishuang
name: Li, Xiaojie
name: Zhang, Chao
Publisher: name: MDPI
Year: 2018
Subjects: multi-regional input-output analysis
CO2 emissions
SO2 emissions
interregional trade

description: CO2 and SO2, while having different environmental impacts, are both linked to the burning of fossil fuels. Research on joint patterns of CO2 emissions and SO2 emissions may provide useful information for decision-makers to reduce these emissions effectively. This study analyzes both CO2 emissions and SO2 emissions embodied in interprovincial trade in 2007 and 2010 using multi-regional input–output analysis. Backward and forward linkage analysis shows that Production and Supply of Electric Power and Steam, Non-metal Mineral Products, and Metal Smelting and Pressing are key sectors for mitigating SO2 and CO2 emissions along the national supply chain. The total SO2 emissions and CO2 emissions of these sectors accounted for 81% and 76% of the total national SO2 emissions and CO2 emissions, respectively.
Anti-inflammatory and hemostatic effects of Linaria reflexa Desf
Creators: name: Cheriet, Thamere
name: Hanfer, Mourad
name: Mancini, Ines
name: Benelhadj, Samiha
name: Laouas, Nour Essabah
name: Ameddah, Souad
name: Menad, Ahmed
name: Seghiri, Ramdane
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: The work presented here was aimed to investigate the in vivo anti-inflammatory and in vitro hemostatic activities of Linaria reflexa extract and to establish the relationship between its bioactivity and chemical composition. Twenty-three secondary metabolites were identified, most of them are good anti-inflammatory agents, in line with data by carrageenin-induced rat paw edema assays of the n-butanol extract showing high anti-inflammatory inhibition (63.90%) of edema swelling in the rat paw at the dose 200 mg/kg after 4 h. Furthermore, both extent of inflammatory response and tissue injury were prevented keeping the levels of rate myeloperoxidase (60.16%) and of malondialdehyde, which is the final product of lipid peroxidation generated by free radicals (58.58%). The same extract showed also a remarkable hemostatic effect established by measuring the coagulation time of decalcified plasma (45 s), related to its flavonoid glycosides content.
Induced superconductivity in the three-dimensional topological insulator HgTe
Creators: name: Maier, Luis
name: Oostinga, Jeroen B.
name: Knott, Daniel
name: Bruene, Christoph
name: Virtanen, Pauli
name: Tkachov, Grigory
name: Hankiewicz, Ewelina M.
name: Gould, Charles
name: Buhmann, Hartmut
name: Molenkamp, Laurens W.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A strained and undoped HgTe layer is a three-dimensional topological insulator, in which electronic transport occurs dominantly through its surface states. In this Letter, we present transport measurements on HgTe-based Josephson junctions with Nb as superconductor. Although the Nb-HgTe interfaces have a low transparency, we observe a strong zero-bias anomaly in the differential resistance measurements. This anomaly originates from proximity-induced superconductivity in the HgTe surface states. In the most transparent junction, we observe periodic oscillations of the differential resistance as function of an applied magnetic field, which correspond to a Fraunhofer-like pattern. This unambiguously shows that a precursor of the Josephson effect occurs in the topological surface states of HgTe.
description: Accepted for publication in Physical Review Letters
Anti-adipogenic and anti-oxidant effects of a standardised extract of Moro blood oranges (Citrus sinensis (L.) Osbeck) during adipocyte differentiation of 3T3-L1 preadipocytes
Creators: name: Tomasello, Barbara
name: Malfa, Giuseppe Antonio
name: La Mantia, Alfonsina
name: Miceli, Natalizia
name: Sferrazzo, Giuseppe
name: Taviano, Maria Fernanda
name: Di Giacomo, Claudia
name: Renis, Marcella
name: Acquaviva, Rosaria
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Particular features in the pulp of blood oranges are marked levels of anthocyanin, a class of polyphenolic compounds well known to exert numerous health-promoting actions on human wellbeing including anti-obesity effects. In this study, we investigated in vitro, the antioxidant and anti-adipogenic activities of Morosil®, a standardised extract of Moro blood oranges. During adipocyte differentiation, 3T3-L1 cells were treated with concentrations of extract containing 2.5, 5, 10, 25 μM of anthocyanins. After seven days of treatment and differentiation, we measured reactive oxygen species production, non-proteic thiol groups content, adipokine secretion and triglyceride accumulation together with mRNA expression of adipogenic transcription factors such as PPARγ, C/EBPα, SREBP-1c. Furthermore, both ACCα, FAS protein expression and citrate synthase activity were measured. Results show that Morosil® exerts antioxidant and anti-adipogenic activities during adipocyte differentiation of 3T3-L1 pre-adipocytes.
title: Convenience of Corruption
Creators: name: Henderson, Diane
Publisher: name: Western Washington University
Year: 2017

description:
Novel excerpt from the work entitled: Convenience of Corruption. Portion of a conspiracy thriller novel that explores the undercurrent of drug and human trafficking occurring daily on a global scale. Selections from the larger project come at roughly the halfway point in the novel. Characters fit into a larger puzzle that involves northern Nevada, High Drug Trafficking Areas, undercover DEA agents, and a global network of cartels (aka global Mafia). Each of the characters is (or has been) on a journey of enlightenment. The manuscript is non-chronological and includes brief factoids and epistolary media that provide some context for the narration that follows. This is a multigenre work with a subtext that addresses race, class, gender, and literacy issues currently in the mainstream.
Proceedings Fourth Workshop on Foundations of Interface Technologies
Creators: name: Bauer, Sebastian
name: Raclet, Jean-Baptiste
Publisher: name: arXiv
Year: 2012
Subjects: subject: Logic in Computer Science (cs.LO)
subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: This volume contains the proceedings of the 4th workshop on Foundations of Interface Technologies (FIT 2012) which was collocated with ETAPS 2012 in Tallinn, Estonia, and took place on March 25, 2012. The aim of this workshop is to bring together researchers who are interested in the formal underpinnings of interface technologies.
A definitional view of Vogt's variant of the Mazur-Ulam theorem
Creators: name: Pambuccian, Victor
Publisher: name: arXiv
Year: 2012
Subjects: subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 51F20, 03C40, 03C75

description: A rephrasing of Vogt's and Skof's version of the Ulam-Mazur theorem as a definability statement.
Additional file 4 of Development and validation of a glioma-associated mesenchymal stem cell-related gene prognostic index for predicting prognosis and guiding individualized therapy in glioma
Creators: name: Peng, Zesheng
name: Wu, Yuxi
name: Wang, Jiajing
name: Gu, Sujie
name: Wang, Yihao
name: Xue, Bingzhou
name: Fu, Peng
name: Xiang, Wei
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Additional file 4. A total of 814 DEGs in microarray.
title: Interactive effects of ocean acidification and ocean warming on Pacific herring  (Clupea pallasi) early life stages
Creators: name: Villalobos, Cristina
Publisher: name: Western Washington University
Year: 2018

description:
The synergy of ocean acidification and ocean warming may lead to negative effects in marine organism responses that would be absent under single stressors. While adult fish are effective acid-base regulators, early life stages may be more susceptible to environmental stressors. Pacific herring are ecologically and economically important forage fish native to the U.S. Pacific Northwest (PNW), and several herring populations in the PNW have experienced reductions in stock abundance. Studies to date have focused on Atlantic herring, and little is known about the response of Pacific herring to ocean acidification and warming. Therefore, this study focused on the combined effects of ocean acidification and warming on Pacific herring early life stages. We incubated Pacific herring embryos under a factorial design of two temperature (10°C, 16°C) and two pCO2 (600 µatm, 1200 µatm) treatments from fertilization until hatch (11 to 15 days depending on temperature). Elevated pCO2 was associated with a small increase in embryo mortality. However, elevated temperature was associated with greater embryo mortality, greater embryo heart rates and yolk areas upon hatch, lower percent normal hatch, and decreased larval lengths. The interaction of elevated temperature and pCO2 was associated greater embryo respiration rates and yolk areas. This study indicates that temperature will likely be the primary global change stressor affecting Pacific herring embryology, and interactive effects with pCO2 may introduce additional challenges.
Additional file 5 of Development and validation of a glioma-associated mesenchymal stem cell-related gene prognostic index for predicting prognosis and guiding individualized therapy in glioma
Creators: name: Peng, Zesheng
name: Wu, Yuxi
name: Wang, Jiajing
name: Gu, Sujie
name: Wang, Yihao
name: Xue, Bingzhou
name: Fu, Peng
name: Xiang, Wei
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Additional file 5. Figure S1: Univariate Cox regression analysis of 54 DEGs in the TCGA (A) and CGGA325 (B) cohorts.
Cytotoxicity of isoflavones from Millettia dura
Creators: name: Buyinza, Daniel
name: Yang, Li Jun
name: Derese, Solomon
name: Ndakala, Albert
name: Coghi, Paolo
name: Heydenreich, Matthias
name: Wong, Vincent Kam Wai
name: Möller, Heiko M.
name: Yenesew, Abiy
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: The first phytochemical investigation of the flowers of Millettia dura resulted in the isolation of seven isoflavones, a flavonol and a chalcone. Eleven isoflavones and a flavonol isolated from various plant parts from this plant were tested for cytotoxicity against a panel of cell lines, and six of these showed good activity with IC50 values of 6-14 μM. Durmillone was the most active with IC50 values of 6.6 μM against A549 adenocarcinomic human alveolar basal epithelial cancer cell line with low cytotoxicity against the non-cancerous cell lines BEAS-2B (IC50 = 58.4 μM), LO2 hepatocytes (IC50 78.7 μM) and CCD19Lu fibroblasts (IC50 >100 μM).
Additional file 1 of In the presence of non-neutralising maternally derived antibodies, intradermal and intramuscular vaccination with a modified live vaccine against porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) induce similar levels of neutralising antibodies or interferon-gamma secreting cells
Creators: name: Aguirre, Laia
name: Li, Yanli
name: Baratelli, Massimiliano
name: Martín-Valls, Gerard
name: Cortey, Martí
name: Miranda, Joel
name: Martín, Marga
name: Mateu, Enric
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 1
Escherichia coli activity characterization using a laser dynamic speckle technique
Creators: name: Ramírez-Miquet, Evelio E.
name: Martí-López, Luis
name: Contreras-Alarcón, Orestes R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Optics (physics.optics)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences

description: The results of applying a laser dynamic speckle technique to characterize bacterial activity are presented. The speckle activity was detected in two-compartment Petri dishes. One compartment was inoculated and the other one was left as a control blank. The speckled images were processed by the recently reported temporal difference method. Three inoculums of 0.3, 0.5, and 0.7 McFarland units of cell concentration were tested; each inoculum was tested twice for a total of six experiments. The dependences on time of the mean activity, the standard deviation of activity and other descriptors of the speckle pattern evolution were calculated for both the inoculated compartment and the blank. In conclusion the proposed dynamic speckle technique allows characterizing the activity of Escherichia coli bacteria in solid medium.
description: 5 pages
Two amide glycosides from Portulaca oleracea L. and its bioactivities
Creators: name: Liu, Xilong
name: Wu, Haibo
name: Tao, Xiaojun
name: Ying, Xixiang
name: Stien, Didier
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology

description: Two novel amide glycosides, named oleraciamide E (1) and oleraciamide F (2), were isolated from the Portulaca oleracea L. Their structures were determined by means of 1D and 2D NMR spectroscopic and UHPLC-ESI-TOF-MS methods. Oleraciamide E (1) exhibited anticholinesterase activity with IC50 values of 52.43 ± 0.33 μM, and presented scavenging activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical quenching assay, with the IC50 values of 24.64 ± 0.33 μM.
Stability of the genetic code and optimal parameters of amino acids
Creators: name: Chechetkin, V. R.
name: Lobzin, V. V.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantitative Methods (q-bio.QM)
subject: FOS: Biological sciences

description: The standard genetic code is known to be much more efficient in minimizing adverse effects of misreading errors and one-point mutations in comparison with a random code having the same structure, i.e. the same number of codons coding for each particular amino acid. We study the inverse problem, how the code structure affects the optimal physico-chemical parameters of amino acids ensuring the highest stability of the genetic code. It is shown that the choice of two or more amino acids with given properties determines unambiguously all the others. In this sense the code structure determines strictly the optimal parameters of amino acids. In the code with the structure of the standard genetic code the resulting values for hydrophobicity obtained in the scheme leave one out and in the scheme with fixed maximum and minimum parameters correlate significantly with the natural scale. This indicates the co-evolution of the genetic code and physico-chemical properties of amino acids.
description: 9 pages, 3 figures
Interferon Independent Non-Canonical STAT Activation and Virus Induced Inflammation
Creators: name: Nan, Yuchen
name: Wu, Chunyan
name: Zhang, Yan-Jin
Publisher: name: MDPI
Year: 2018
Subjects: Interferons
JAK/STAT signaling
non-canonical STAT activation
viral antagonism
inflammation

description: Interferons (IFNs) are a group of secreted proteins that play critical roles in antiviral immunity, antitumor activity, activation of cytotoxic T cells, and modulation of host immune responses. IFNs are cytokines, and bind receptors on cell surfaces to trigger signal transduction. The major signaling pathway activated by IFNs is the JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathway, a complex pathway involved in both viral and host survival strategies. On the one hand, viruses have evolved strategies to escape from antiviral host defenses evoked by IFN-activated JAK/STAT signaling. On the other hand, viruses have also evolved to exploit the JAK/STAT pathway to evoke activation of certain STATs that somehow promote viral pathogenesis. In this review, recent progress in our understanding of the virus-induced IFN-independent STAT signaling and its potential roles in viral induced inflammation and pathogenesis are summarized in detail, and perspectives are provided.
Isolation and structure determination of new chymotrypsin inhibitory peptides streptopeptolins B and C
Creators: name: Tiwari, Ankit
name: Kaweewan, Issara
name: Miyake, Yuto
name: Hemmi, Hikaru
name: Kodani, Shinya
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 60506 Virology

description: New chymotrypsin inhibitory peptides named streptopeptolins B and C were isolated from Streptomyces olivochromogenes. Structures of streptopeptolins B and C were determined to be cyclic depsipeptides possessing 3-amino-6-hydroxy-2-piperidone unit by interpretation of NMR spectra and ESI-MS. Streptopeptolins B and C showed inhibitory activities to chymotrypsin with IC50 of 8.0 and 12.0 μg/mL, respectively.
Evolution from a nodeless gap to d(x2-y2) form in underdoped La(2-x)SrxCuO4
Creators: name: Razzoli, E.
name: Drachuck, G.
name: Keren, A.
name: Radovic, M.
name: Plumb, N. C.
name: Chang, J.
name: Mesot, J.
name: Shi, M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Using angle-resolved photoemission (ARPES), it is revealed that the low-energy electronic excitation spectra of highly underdoped superconducting and non-superconducting La(2-x)SrxCuO4 cuprates are gapped along the entire underlying Fermi surface at low temperatures. We show how the gap function evolves to a d(x2-y2) form as increasing temperature or doping, consistent with the vast majority of ARPES studies of cuprates. Our results provide essential information for uncovering the symmetry of the order parameter(s) in strongly underdoped cuprates, which is a prerequisite for understanding the pairing mechanism and how superconductivity emerges from a Mott insulator.
description: 5 pages, 4 figures
Nutritional evaluation of elongate mudskipper Pseudapocryptes elongatus (Cuvier, 1816) from Diamond Harbor, West Bengal, India
Creators: name: Mahadevan, Gopalan
name: Pouladi, Mojtaba
name: Stara, Alzbeta
name: Faggio, Caterina
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Plant Biology

description: The mudskipper Pseudapocryptes elongatus (Cuvier, 1816), (Gobiidae) are caught throughout the year and they are considered as most edible mudskipper species in Sundarbans. They are targeted by special gears and sold live in large quantities in the local markets of Diamond Harbor, Namkhana and Kakdweep. The adult P. elongatus (14–18 cm total length) specimens were purchased from the Diamond Harbor landing center for evaluation of its biochemical components such as Protein, carbohydrate, lipid, amino acid, fatty acid, vitamin, and minerals. The percentage composition of protein was high (27.34%) followed by the carbohydrate (4.57%) and lipid (2.72%). The amino acids both essential (47.72%) and non-essential (42.91%) was found adequate. Among fatty acids, polyunsaturated fatty acid (PUFA) was found the maximum (31.55%) followed by saturated fatty acid (SFA; 27.66%) and monounsaturated fatty acid (MUFA; 19.55%). Vitamin A (112.5 IU/100 g) and Ca2+ (62.2 mg/100 g) were found maximum levels. The present finding supports that P. elongatus is valuable for human consumption due to its high-quality protein with well-balanced amino acids.
On the solutions of the Yang-Baxter equations with general inhomogeneous eight-vertex $R$-matrix: Relations with Zamolodchikov's tetrahedral algebra
Creators: name: Khachatryan, Sh.
name: Sedrakyan, A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present most general one-parametric solutions of the Yang-Baxter equations (YBE) for one spectral parameter dependent $R_{ij}(u)$-matrices of the six- and eight-vertex models, where the only constraint is the particle number conservation by mod(2). A complete classification of the solutions is performed. We have obtained also two spectral parameter dependent particular solutions $R_{ij}(u,v)$ of YBE. The application of the non-homogeneous solutions to construction of Zamolodchikov's tetrahedral algebra is discussed.
description: 36 pages
title: Cross-sectional scat sampling reveals intrapopulation feeding diversity in a marine predator
Creators: name: Voelker, Madelyn
Publisher: name: Western Washington University
Year: 2018

description:
Harbor seals (Phoca vitulina) have substantial impacts on species of concern. To understand and predict the impact that harbor seals have in their communities, we need to describe their level of individual specialization because it can affect food web dynamics, responses to changes in prey availability, and the accuracy of predictive models. I estimated intrapopulation feeding diversity, a proxy for individual specialization, of P. vitulina in the Salish Sea relative to sex, time, and location using repeated cross-sectional sampling of scat. Based on 1,083 scat samples collected from five haul-out sites over the course of four, non-sequential years, diet was quantified using traditional and metabarcoding techniques, and sex was determined using a molecular assay. Though variable spatially and temporally, high levels of specialization at a short-time scale (24 - 48 hours) ( = 0.392, 95% CI = 0.013, R = 100,000), combined with previous knowledge of P. vitulina feeding strategies, suggested that specialization was pervasive in Salish Sea populations. Males showed less specialization than females, particularly in the summer and fall, and demersal and benthic prey species were correlated with higher levels of diversity. These results suggest that although females consumed a wider range of prey species than males, they had a higher degree of specialization, likely driven by consumption of benthic species. Further, this finding also suggests benthic species likely require more specialized foraging strategies and that there are trade-offs between a pelagic and benthic foraging style for P. vitulina. Differential specialization on prey species as well as between sexes of P. vitulina indicate that predator-prey interactions are not well understood. Therefore, the likelihood of specialist versus generalist interactions with a prey species should be considered when management decides how to address P. vitulina influence on prey of conservation concern.
Additional file 6 of Development and validation of a glioma-associated mesenchymal stem cell-related gene prognostic index for predicting prognosis and guiding individualized therapy in glioma
Creators: name: Peng, Zesheng
name: Wu, Yuxi
name: Wang, Jiajing
name: Gu, Sujie
name: Wang, Yihao
name: Xue, Bingzhou
name: Fu, Peng
name: Xiang, Wei
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Plant Biology
subject: Computational Biology

description: Additional file 6. Figure S2: Validation of the GA-MSCRGPI in the TCGA and CGGA325 cohorts. (A, E) The expression comparison of 8 selected GA-MSCRGs between different grade glioma tissues in TCGA and CGGA325 cohort (G2: WHO grade II, G3: WHO grade III, G4: WHO grade IV; **p < 0.01,***p < 0.001, and ns No significance). (B, F) Kaplan‒Meier curves of GA-MSCRGPI subgroups for survival. (C, G) The distribution plots of GA-MSCRGPI, survival status and expression of 8 selected GA-MSCRGs. (D, H) ROC curve analysis of GA-MSCRGPI in predicting 2-, 3- and 5-year OS.
Additional file 3 of In the presence of non-neutralising maternally derived antibodies, intradermal and intramuscular vaccination with a modified live vaccine against porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) induce similar levels of neutralising antibodies or interferon-gamma secreting cells
Creators: name: Aguirre, Laia
name: Li, Yanli
name: Baratelli, Massimiliano
name: Martín-Valls, Gerard
name: Cortey, Martí
name: Miranda, Joel
name: Martín, Marga
name: Mateu, Enric
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 3
Trypanocidal Trixikingolides From Trixis Vauthieri
Creators: name: Junior, Policarpo Ademar Sales
name: Zani, Carlos Leomar
name: de Siqueira, Ezequias Pessoa
name: Kohlhoff, Markus
name: Marques, Fátima Regina
name: Caldeira, Alisson Samuel Portes
name: Cota, Betânia Barros
name: Maia, Daniela Nabak Bueno
name: Tunes, Luiza Guimarães
name: Murta, Silvane Maria Fonseca
name: Alves, Tânia Maria Almeida
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Computational Biology

description: Chagas disease is an illness caused by the protozoan parasite Trypanosoma cruzi. Only two drugs are available, with the drawback of low rate of cure in the chronic phase of the disease and undesirable side effects. These facts highlight the need to find new compounds for Chagas disease chemotherapy. We describe the isolation and identification of an inseparable mixture of two new trixikingolides from Trixis vauthieri, a plant from family Asteraceae, which present outstanding in vitro trypanocidal activity, with IC50 value of 0.053 µM against the intracellular trypomastigotes and amastigotes forms of T. cruzi infecting L929 cells. The IC50 of the mixture against the host cells is 68 times higher and about 70 times more potent than benznidazole, the reference drug used as control at the experiments. The next step, which depends on obtaining larger quantities of the mixture, is to test it on mice infected with T. cruzi.
Casimir effect of an ideal Bose gas trapped in a generic power-law potential
Creators: name: Lin, Tongling
name: Su, Guozhen
name: Wang, Qiuping A.
name: Chen, Jincan
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: The Casimir effect of an ideal Bose gas trapped in a generic power-law potential and confined between two slabs with Dirichlet, Neumann, and periodic boundary conditions is investigated systematically, based on the grand potential of the ideal Bose gas, the Casimir potential and force are calculated. The scaling function is obtained and discussed. The special cases of free and harmonic potentials are also discussed. It is found that when TTc, the Casimir force is an exponential decay function; and when T>>Tc, the Casimir force vanishes.
description: 5 pages, 1 figure
Additional file 3 of In-silico analysis of heat shock transcription factor (OsHSF) gene family in rice (Oryza sativa L.)
Creators: name: Shamshad, Areeqa
name: Rashid, Muhammad
name: Zaman, Qamar uz
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3.
title: Αξιολόγηση επιχειρηματικής βιωσιμότητας
title: Evaluation of corporate sustainability
Creators: name: Ξηρακης Νικολαος
Publisher: name: Technical University of Crete
Year: 2020

description: Είναι γεγονός ότι στο σύγχρονο οικονομικό και επιχειρηματικό περιβάλλον κύριος είναι ο προβληματισμός της ανταγωνιστικότητας των επιχειρήσεων και συγχρόνως της βιωσιμότητας αυτών των εταιρειών - οικονομικών μονάδων σύμφωνα με τις αρχές του Οικουμενικού Συμφώνου του ΟΗΕ. Με γνώμονα τον παραπάνω αυτό προβληματισμό στη παρούσα εργασία αναλύεται η επιχειρηματική βιωσιμότητα (corporate sustainability), ενώ μελετάται η σύνδεση αυτής με τη βιώσιμη ανάπτυξη μίας οικονομίας. Δίδονται διάφοροι ορισμοί και ερμηνείες του όρου της βιωσιμότητας, της επιχειρηματικής βιωσιμότητας, καθώς και της βιώσιμης ανάπτυξης στα πλαίσια μίας οικονομίας. Στη διεθνή και εγχώρια βιβλιογραφία οι διαστάσεις και τα κριτήρια που συνδέονται με τη επιχειρηματική βιωσιμότητα είναι κυρίως Περιβαλλοντικά, Κοινωνικά καθώς και Οικονομικά - Χρηματοοικονομικά. Ωστόσο στη παρούσα εργασία εστιάζεται το ενδιαφέρον σε διαστάσεις που είναι συνδεδεμένες με την Οικονομία, τη Γνώση και τα Χρηματοοικονομικά στοιχεία μίας εταιρείας - οικονομικής μονάδας, καθώς επίσης και σε ζητήματα που αφορούν την οργάνωση και λειτουργία αυτής. Κάποιες από τις κύριες διαστάσεις που συνδέονται με την επιχειρηματική βιωσιμότητα και τη στρατηγική μίας εταιρείας και θα μελετηθούν αφορούν τα εξής: Χρηματοοικονομική - Οικονομική λειτουργία και Επιδόσεις, Καινοτομία και Έρευνα και Ανάπτυξη, διαχείριση Διαδικασιών, Διοίκηση Ανθρώπινου Δυναμικού καθώς και οι διαστάσεις των Πελατών και των Προμηθευτών μίας οικονομικής μονάδας. Έτσι με γνώμονα το Ευρωπαϊκό μοντέλο αξιολόγησης (EFQM), το Αμερικανικό βραβείο Malcolm Baldridge, τη μεθοδολογία της Ισορροπημένης Κάρτας επιδόσεων των Norton και Kaplan και την ελληνική και διεθνή βιβλιογραφία θα καθοριστούν οι διαστάσεις και τα κριτήρια της επιχειρηματικής βιωσιμότητας που έχουν άμεση σχέση με την ίδια την εταιρεία - οικονομική μονάδα και αφορούν κυρίως παράγοντες οικονομικούς - χρηματοοικονομικούς και σε παράγοντες που σχετίζονται με την εσωτερική λειτουργία και οργάνωση αυτής. Αυτά τα μοντέλα αξιολόγησης αποτελούν ένα χρήσιμο εργαλείο ενημέρωσης καθώς και στοχοθέτησης της στρατηγικής και της βιωσιμότητας των επιχειρήσεων. Τέλος παρουσιάζεται και αναλύεται μελέτη περίπτωσης μιας βιομηχανικής επιχείρησης με χρήση σχετικών δεικτών βιωσιμότητας από τις διαστάσεις που έχουν αναφερθεί, μετρώντας έτσι τις οικονομικές επιδόσεις άμεσα και τις κοινωνικές και περιβαλλοντικές επιδόσεις έμμεσα σε συνάφεια με τα παραπάνω μοντέλα αξιολόγησης.