cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Structural and Dynamical Properties of Nucleic Acid Hairpins Implicated in Trinucleotide Repeat Expansion Diseases
Creators: name: Pan, Feng
name: Weninger, Keith
name: Sagui, Celeste
name: Roland, Christopher
name: Xu, Pengning
Publisher: name: Multidisciplinary Digital Publishing Institute (MDPI)
Year: 2024

description: Dynamic mutations in some human genes containing trinucleotide repeats are associated with severe neurodegenerative and neuromuscular disorders—known as Trinucleotide (or Triplet) Repeat Expansion Diseases (TREDs)—which arise when the repeat number of triplets expands beyond a critical threshold. While the mechanisms causing the DNA triplet expansion are complex and remain largely unknown, it is now recognized that the expandable repeats lead to the formation of nucleotide configurations with atypical structural characteristics that play a crucial role in TREDs. These nonstandard nucleic acid forms include single-stranded hairpins, Z-DNA, triplex structures, G-quartets and slipped-stranded duplexes. Of these, hairpin structures are the most prolific and are associated with the largest number of TREDs and have therefore been the focus of recent single-molecule FRET experiments and molecular dynamics investigations. Here, we review the structural and dynamical properties of nucleic acid hairpins that have emerged from these studies and the implications for repeat expansion mechanisms. The focus will be on CAG, GAC, CTG and GTC hairpins and their stems, their atomistic structures, their stability, and the important role played by structural interrupts.
Reason, necessity and genocide.
Creators: name: Lancaster, Philip Charles.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2000
Subjects: subject: Philosophy.

description: This work examines core assumptions of the rationalism that underlies liberal political theory by placing it against the background of a dramatic historical phenomenon---genocide. An attempt is made to draw on historical accounts of two genocides to develop a critique of liberal political theory as it has been articulated during the latter years of the 20th Century by John Rawls. Ultimately, this thesis attempts to sort out the conceptual problems arising at the junction point of normative and descriptive theories of politics and argues that the basic elements of both kinds theories would benefit greatly from closer attention to history. The first chapter is devoted to a discussion of the ways in which political reason can be adapted to the needs of state and suggests that there are problems associated with the attempt to universalize the notion of human rights across a community of nations lacking the basic contextual requirements for rights. Chapter two considers the uncomfortable fit between political structure and value in liberal political theory. It argues that the administrative structure of states now exists as an important part of contemporary formal reality and thus ought to be a critical element in any serious study of politics. An argument begins here that works towards the final conclusion that states constitute an arena within which individualist and collectivist values collide. The third chapter examines the relationship between liberal values and rationality. It includes a technical discussion of Max Weber's theory of rationality but limits the discussion to political applications. This chapter raises a series of questions about the concept of rationality used in the construction of political theory. Chapters four, five and six examine the complications that arise when a liberal perspective is taken to issues of ontological existence, community values and the powers inhering in states to shape identity frames in the interests of administrative efficiency. This leads into a more technical discussion of rationality as represented in the theories of John Rawls and Alan Gewirth that is contained in the seventh chapter. Chapters eight and nine are devoted to discussions of elements of the Holocaust and the Rwandan genocide respectively. Both examples are used as a means of illustrating the complex power relations arising out of the various forms of collective agency needed to sustain state sovereignty and which complicate political theory far beyond the explanatory power of liberal rationalism. The examples are used to argue that theories based on notions of disassociated rational persons just fail to support their normative conclusions. The final chapter argues for a re-examination of the way in which political theory is read and suggests that liberal theory, in particular, tends towards abstraction in ways that limit its usefulness as either explanatory or normative theory.
Problem-based Learning in a Box: Lessons learned from an Educational Design Experiment
Creators: name: Davidsen, Jacob
name: Andersen, Pernille Viktoria Kathja
name: Christiansen, Ellen
Publisher: name: Journal of Problem Based Learning in Higher Education
Year: 2019

description: In this study, we present an educational design experiment seeking to promote interaction and knowledge sharing in groups and to establish a sense of community among students during a semester at Aalborg University, Denmark. The experiment is materialised as a tangible artefact in the form of a colourful box with materials and texts. Some of the materials are oriented towards supporting the collaborative activities taking place in the group, while others are intended to support individual groups in displaying a visual identity and the public historical trajectory of their problem-based learning process to other groups or peers. The lessons learned from the experiment highlight that educational designs are difficult to implement in practice if it is not mandatory for the students, teachers and supervisors to take part. Furthermore, we imagined the box as a toolbox to support process-related aspects of problem-based learning, such as collaborative interaction, problem formulation and the collaborative learning process itself, whereas the students requested specific ‘how to’ materials for certain project activities – focusing more on the semester product and the outcome of problem-based learning.
description: Journal of Problem Based Learning in Higher Education, Vol. 7 No. 1 (2019)
Project–based Learning for Teaching Transmedia Communication
Creators: name: Bron, Maximiliano
name: Gértrudix Barrio, Manuel
Publisher: name: Journal of Problem Based Learning in Higher Education
Year: 2019

description: This article narrates the experience and shows the results of research study conducted at the National University of La Rioja (Argentina) where Project-Based Learning (PBL) strategies were implemented for the making of a transmedia documentary which was central to the students training in a particular class, which is part of the last year of the Social Communication Programme.
description: Journal of Problem Based Learning in Higher Education, Vol. 7 No. 1 (2019)
Individual Reflection Paper – Supporting Student's Learning in the Critical Phase of Self-directed Learning in PBL
Creators: name: Johansson, Madelaine
name: Svensson, Teresia
Publisher: name: Journal of Problem Based Learning in Higher Education
Year: 2019

description: Supporting and assessment of students’ preparation and learning process in problem-based learning (PBL) tutorials has long been a challenge. We present a modified PBL model focussing on the specific critical phase in the PBL process, the self-directed learning phase in between tutorial meetings. The modified seven step PBL model including an Individual reflection paper (IRP) is presented as well as students’ perspectives on the implementation of IRP and information literacy, knowledge gathering, and PBL tutorial work. The assessment of PBL work is complex, and the ways in which IRPs support the tutor’s role as an examiner is beyond the scope of the current study. However, it seems that the students experienced assessment of the IRPs as part of their as a positive driving force in their learning process.
description: Journal of Problem Based Learning in Higher Education, Vol. 7 No. 1 (2019)
รูปแบบการพัฒนาทักษะการบริหารของผู้ประกอบการอุตสาหกรรมท่องเที่ยวพื้นที่สามเหลี่ยมอันดามัน
Creators: name: จุรีรัตน์ ว่องปลูกศิลป์
Publisher: name: มหาวิทยาลัยนราธิวาสราชนครินทร์
Year: 2567
Subjects: รูปแบบการพัฒนาทักษะการบริหาร
ผู้ประกอบการ
การท่องเที่ยวสามเหลี่ยมอันดามัน

description: วารสารมหาวิทยาลัยนราธิวาสราชนครินทร์ สาขามนุษยศาสตร์และสังคมศาสตร์, 11, 2, 209-227
The importance of family functioning and peer relations for children's internalizing and externalizing behaviours.
Creators: name: Chappell, Dianne E.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Psychology, Developmental.

description: Two studies are reported here. The purpose of the first study was to examine the relative impact of the family climate (defined in terms of marital satisfaction, marital conflict, parental psychological distress, and SES) and the peer climate (defined in terms of peer likeability) on children's adjustment (measured by internalizing and externalizing behaviours) for 89 children from grades 6 to 11. Two path analytic models were assessed. The first assessed a single process family model which hypothesized that family functioning would have a direct effect on children's adjustment, but peer relations would have no significant effect on children's adjustment. The second model hypothesized dual processes, that is, that both family functioning and peer relations would predict children's adjustment. Results indicated strong support for a single process family model when data using fathers as informants about family functioning and children's adjustment were examined. Results from data which used mothers as informants about family variables and children's adjustment provided support for a dual process model, in which both family and peers made significant contributions to child adjustment problems. When either mothers or fathers provided information about the family, and peers provided outcome scores, there was evidence for a single process peer model. In the second study, a mediational model was assessed. It was hypothesized that overt marital hostility would mediate the relationship between marital satisfaction and children's adjustment for 277 children from grades 6 to 11. Results indicated that marital hostility mediated the relationship between marital satisfaction and children's adjustment when parents provided the information regarding marital functioning and children's adjustment. However, when peer information about aggression and withdrawal was used as outcome measures, the relationship between marital satisfaction and children's adjustment was no longer significant. Some gender differences were also noted, indicating that marital hostility mediated the relationship between marital satisfaction and internalizing and externalizing behaviours differently for boys and girls. (Abstract shortened by UMI.)
Altruistic Endgame Hypothesis: Community Music as Model for the Introduction and Enactment of Triune Phenomenology
Creators: name: Hollander, Eric James
Publisher: name: Brandeis University
Year: 2023
Subjects: Augustinian Spirituality
Charles Ives
Community Music
Phenomenology
Theology
Musicology

description: If music is not a thing, what is it and how can it be described? As performers and listeners, we know music as a feeling, an existential condition. But can we comprehend more fully, more literally these engagements? My project positions the music of Charles Ives as a set of models for confronting challenging concepts that lie at the controversial crossroads of phenomenology and theology and for plunging through this juncture so as to lead towards a new ontological definition of music. In its course, the dissertation explores the viability of employing both phenomenological ideas and terminology from Community Music Therapy for music analysis - in general and of Ives' music specifically. I use ideas and language from phenomenology, Guattari and Deleuze, Community Music (Therapy), Augustinian theology, studies on sound and affect, and work done in phenomenological and Guattarian-Deleuzian music analysis as a primary way-in to "The Harvest Home Chorales", "Central Park in the Dark", and "Tom Sails Away" (from 19 Songs). Then, I position these as situations for phenomenological description and thereby models for practicable engagement with philosophical ideas that have hitherto seemed the exclusive tasks of transcendent meditations or spiritual revelations.
description: It also seems that there is more in phenomenology proper (Heidegger, Husserl, Merleau-Ponty, etc.) that music analysis has yet to explore. With my dissertation, I hope to confront several of the most challenging philosophical areas (that remain hazy even within philosophical texts) with music as my model and hopefully shed some light - both for musicians and philosophers. Using music in this way has been very helpful for me when thinking about certain ideas like intersubjectivity, multiple ecstatic schema within unified temporality, dimensions of being, and the potential for existential transcendence (momentary or otherwise). Through this interdisciplinary exploration, I am left with a new definition of music that feels sincere.
description: It is important for me to engage phenomenological ideas in a non-subjective (communal) experience, and that's where music helps! The dissertation's conclusion features a brief positioning of the "Universe Symphony" to illustrate certain take-aways and draw the project back to its initial musicological objectives.
Scaffolding in PBL: A Case-study in Facilitated Soft Skill-set Learning amongst Adult Learners in Taiwan's Vocational Higher Education
Creators: name: Lee, Sabrina Chia Jung
Publisher: name: Journal of Problem Based Learning in Higher Education
Year: 2019

description: Taiwan’s university-level vocational education is faced with a growing need to strengthen students’ soft skills as a means to increase job market eligibility. Students in Taiwan are usually not equipped with group learning skills in junior and senior high school education. These learning skills, however, are an essential component of a successful PBL course, according to past research. This case study describes how a PBL course that adopted various scaffolding strategies helped vocational students improve soft skills associated with real-life issues in the workplace. The adult learners participating in the tailored PBL course were PBL novices, yet their feedback on PBL effectiveness was positive. The success of the PBL course was attributed to 1) the use of effective scaffolding strategies, and 2) learner readiness in the skills needed for group learning.
description: Journal of Problem Based Learning in Higher Education, Vol. 7 No. 1 (2019)
DIRECTED EVOLUTION OF GLUTEN DEGRADING PROTEASES
Creators: name: Xiao, Lufan
Publisher: name: Brandeis University
Year: 2025
Subjects: Celiac
digestion
directed evolution
Gluten
Protease
Protein Engineering
Biophysics

description: Gut digestion of gluten releases immunogenic peptides. Among the digestion products, a proline and glutamine-rich 33-mer peptide from wheat α-gliadin triggers celiac disease. Despite multiple proteases from different families being investigated for degradation of the peptide, no FDA-approved protease treatment towards celiac disease is available to date. Here we identified three naturally occurring proteases from the aspartic, cysteine, and serine protease family as model enzymes for directed evolution campaigns: pepsin from human, EP-B2 from barley, and POPB from G. marginata. We expressed and purified these recombinant model enzymes in E. coli strains, determined their respective activity towards a fluorogenic model substrate resembling the 33-mer immunogenic epitope, designed a droplet microfluidics screening workflow, and prepared mutagenic libraries for high-throughput droplet fluorescence sorting. We aim to develop a gluten-detoxifying protease through directed evolution that is active at gastric pH and capable of degrading gluten immunogenic peptides.
The Abbotsford Post
Creators: name: (:Null)
Publisher: name: Abbotsford, B.C. : J.A. Bates
Year: 2017

description: The Abbotsford Post was published in Abbotsford, in the Fraser Valley region of southwestern British Columbia. The Post was published and edited by John Alexander Bates, and it was the first paper targeted specifically at the Abbotsford area. The paper has since been bought and sold a number of times, and continues to be published to this day under the title of the Abbotsford News.
A Scoping Review of Individual Differences in Information Seeking Behavior and Retrieval Research between 2000 and 2015
Creators: name: O'Brien, Heather, 1977-
name: Dickinson, R.
name: Askin, Nicole
Publisher: name: Elsevier
Year: 2021

description: Individual differences have long been of interest in information science to design information systems and services for specific populations. Yet what individual differences make a difference to search outcomes, both across applications and for diverse user groups? A scoping study of information seeking and retrieval research (2000-2015) was conducted involving systematic searches in eight scholarly databases. Over 2100 articles were screened based on title, abstract, and full-text using specified inclusion criteria, resulting in 223 papers for analysis. Data were extracted to provide an overview of the literature, including types of individual differences studied, publication volume over time, measures, sample, and study outcomes. Findings are inconclusiveness regarding what individual differences affect search outcomes, and raise issues around measurement and generalizability. This study represents an essential first step to developing a more systematic investigation of individual differences research and connecting individual research studies to anchor and guide future work.
Connecting Learning Analytics and Problem-Based Learning – Potentials and Challenges
Creators: name: Kilińska, Daria
name: Ryberg, Thomas
Publisher: name: Journal of Problem Based Learning in Higher Education
Year: 2019

description: Learning analytics (LA) are a young but fast-growing field, which, according to some authors, holds big promises for education. Some claim that LA solutions can help measure and support constructivist classrooms and 21st century skills, thus creating a potential of making an alignment between LA and PBL principles and practices. Despite this argument, LA have not yet gained much interest among the Problem-Based Learning (PBL) practitioners and researchers and the possible connections between PBL and LA have not yet been properly explored. The purpose of this paper is, therefore, to investigate how LA can potentially be used to support and inform PBL practice. We do this by identifying central themes that remain constant across various orchestrations of PBL (collaboration, self-directed learning, and reflection) and present examples of LA tools and concepts that have been developed within LA and neighbouring fields (e.g. CSCL) in connection to those themes. This selection of LA solutions is later used as a basis for discussing wider potentials, challenges and recommendations for making connections between PBL and LA.
description: Journal of Problem Based Learning in Higher Education, Vol. 7 No. 1 (2019)
Different levels of let-7d expression modulate response of FaDu cells to irradiation and chemotherapeutics
Creators: name: Lamperska, Katarzyna Monika
name: Kolenda, Tomasz
name: Teresiak, Anna
name: Kowalik, Anna
name: Kruszyna-Mochalska, Marta
name: Jackowiak, Weronika
name: Blizniak, Renata
name: Przybyla, Weronika
name: Kapalczynska, Marta
name: Kozlowski, Piotr
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: biomarkers
subject: cancer
subject: miRNA
subject: let-7d
subject: therapeutic
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten

description: The implication of the let-7 family in cancer development is multifaceted. The family acts as tumor suppressor miRNA although overexpression of let-7 has also been described in many types of cancer, including head and neck squamous cell carcinoma (HNSCC). The aim of this study includes whether different expression levels of let-7d has an influence on chemo- and radiosensitivity. FaDu cell line models with a gradually increased level of let-7d (models from A to E) were generated with the lentiviral system. Expression levels of pluripotency, chemo-radioresistance/apoptosis, and targets of mRNAs were analyzed by real-time reverse transcription-PCR (qRT-PCR). Radiosensitivity was analyzed using a clonogenic assay after irradiation. Response to cisplatin, 5-FU, doxorubicin, and paclitaxel was done with MTT assay. Statistically significant decrease of K-RAS (p = 0.0369) and CASPASE3 (p = 0.0342) were observed with the growing expression level of let-7d. Cisplatin, 5-FU and doxorubicin caused similar decreased of cell survival with the increase of let-7d level (p = 0.004, post-trend p = 0.046; p = 0.004, post trend p = 0.0005 and p<0.0001, post trend p = 0.0001, respectively). All models were resistant to paclitaxel, irrespective of let-7d expression levels. Only two of the generated models (A and C) were radiosensitive (p = 0.0002). Conclusion: the above results indicated that the level of let-7d expression is an important factor for cell response to irradiation and chemotherapeutics.
Web 2.0 Technologies Supporting Problem Based Learning: A Systematic Literature Review
Creators: name: Ünal, Erhan
Publisher: name: Journal of Problem Based Learning in Higher Education
Year: 2019

description: The purpose of this study was to investigate the study general trends with regards to Web 2.0 technologies supporting problem-based learning (PBL) environments. A systematic literature review was applied to analyse studies published in this area, with a total of 18 articles included in the review. The content analysis method was applied in the study. The results indicated that the emergence of studies in this area was in 2007. The studies were conducted in different research domains. The qualitative research paradigm was the most frequently used, and higher education students the most preferred study group in the articles. Wiki was the most integrated Web 2.0 tool in PBL environments. Interview was the most selected data collection tool, with qualitative analysis methods the most used in the articles. The variables investigated the most in the studies were perception about the effectiveness of PBL and achievement. The effectiveness of Web 2.0 technologies supporting PBL was the most frequently reported finding. Therefore, the current study was able to identify the recent trends in this research area. Based on the results, the study put forward suggested implications for future research.
description: Journal of Problem Based Learning in Higher Education, Vol. 7 No. 1 (2019)
Temporal and Spatial Variations in Microplastic Concentrations in Small Headwater Basins in the Southern Blue Ridge Mountains, North Carolina, USA
Creators: name: Spafford, Juliet
name: Youker, Robert
name: Jarrett, Reagan
name: Randall, Georgeanna
name: Gaesser, Megan
name: Barrett, Nathaniel
name: Miller, Jerry
name: Gray, Austin
name: Love, Jason
name: Meiri, Noa
name: Hall, Chloe
Publisher: name: Multidisciplinary Digital Publishing Institute (MDPI)
Year: 2024

description: Microplastics (MPs) are ubiquitous contaminants of emerging concern that require additional study in freshwater streams. We examined the spatial-temporal variations in MP concentrations and characteristics within two headwater basins in the Southern Appalachian Mountains of western North Carolina over ~1 year. Atmospheric samples were also collected to determine the significance of atmospheric MP deposition to these relatively small streams. MP concentrations in both basins were within the upper quartile of those reported globally, reaching maximum values of 65.1 MPs/L. Approximately 90% of MPs were fibers. MP composition was dominated by polystyrene, polyamides, and polyethylene terephthalate. Spatially, concentrations were highly variable and increased with development, indicating anthropogenic inputs from urbanized areas. MP concentrations were also elevated in forested tributary subbasins with limited anthropogenic activity, suggesting atmospheric deposition was an important MPs source. Significant atmospheric inputs are supported by high atmospheric depositional rates (ranging between 7.6 and 449.8 MPs/m2/day across our study sites) and similarities in morphology, color, and composition between atmospheric and water samples. Temporally, MP concentrations during storm events increased, decreased, or remained the same in comparison to base flows, depending on the site. The observed spatial and temporal variations in concentrations appear to be related to the complex interplay between precipitation and runoff intensities, channel transport characteristics, and MP source locations and contributions.
Cellular and cytoskeletal heterogeneity along the rat ventral prostatic duct.
Creators: name: Rouleau, Michèle.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Biology, Animal Physiology.

description: In this study, the ductal heterogeneity in the rat ventral prostate was further investigated in terms of structural elements that make up the different cell types of the prostate as well as cell populations found along prostatic ducts. In addition, effects of androgens were analyzed in specific locations of the ductal-acinar network. The cytokeratin content of the prostate was characterized biochemically and by immunofluorescence and was used as a marker to monitor the behaviour of each cell type after androgen depletion. It was found that the cytokeratin content of basal and luminal epithelial cells are characteristic for each cell type and that these structural proteins constitute good markers for these cell types. Using antibodies specific for basal and luminal epithelial cells, the ratio basal to luminal epithelial cells was shown to vary along the prostatic duct as well as after castration, suggesting a preferential loss of luminal epithelial cells. Based on the observations of the cellular dynamics in the prostate of intact versus castrated rats, a model of regression is proposed. (Abstract shortened by UMI.)
Computational*RAM implementations of vector quantization for image and video compression.
Creators: name: Le, Thinh Minh.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Engineering, Electronics and Electrical.

description: In this thesis, Computational$\sp*$RAM (C$\sp*$RAM) implementations of Vector Quantization for image and video compression is proposed. Vector Quantization (VQ) is a powerful technique for low bit rate image and video compression. The coding performance can be further improved by employing the adaptive techniques at the expense of significant increase in computational complexity. Recently, a number of VLSI architectures for implementing VQ have been reported in the literature. These architectures are not programmable and rather complex. We proposed the mapping of VQ-based image and video compression algorithms on the C$\sp*$RAM architecture. C$\sp*$RAM is a SIMD-memory hybrid where the processing elements are attached to memory columns of a conventional RAM to take advantage of the on-chip high memory bandwidth for parallel computation. Implementation of VQ based on the mean absolute error measure using the C$\sp*$RAM's parallel structure is first presented. This follows with the details of the proposed Modified Scalable VQ algorithm. C$\sp*$RAM implementation of Modified SVQ is a mapping of binary tree onto parallel structure which results in scalable bit stream. We then propose a novel adaptive codebook replenishment VQ and index-based motion estimation (AVQ + ME) algorithm for video compression. Finally, the C$\sp*$RAM implementation of AVQ + ME is presented. Simulation results demonstrate a good coding performance at a significantly reduced computational complexity.
The use of mental skills by male and female athletes.
Creators: name: Stevenson, Mike.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Psychology, Cognitive.

description: The purpose of this study was to gain a better understanding of the relationship between selected independent variables (gender and skill) and mental skills of athletes (goal-setting, self-confidence, commitment, imagery, mental practice, focusing, refocusing, competition planning, activation, relaxation, stress and fear control). The Ottawa Mental Skills Assessment Tool (OMSAT-3*) was administered to a sample of 249 (121 males and 128 females) athletes aged 14 to 19 who participated in sport at either a developing or provincial level in a variety of sports. A gender by skill (2 x 2) MANOVA resulted in a main effect (p < .004) for skill on the goal-setting, commitment, competition planning, focus, and refocus scales, as well as for foundation, cognitive, and psychosomatic skills components: The results imply there were no gender differences in athletes' level and use of mental skills.
A. Giddens et U. Beck : contribution de deux apôtres de la contingence à une sociologie du système pénal.
Creators: name: Cauchie, Jean-François.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Sociology, Criminology and Penology.

description: Proposee sous la forme d'un essai theorique, notre these explore les caracteristiques de nos societes modernes occidentales en vue d'une reflexion sur nos politiques securitaires et nos systemes penaux actuels. Notre problematique touchant tant a la sociologie de la deviance qu'a la sociologie du droit penal, nous preferions parler de contribution a une sociologie du systeme penal. Notre reflexion s'est basee sur les travaux de deux auteurs s'interessant aux questions de premiere et seconde modernite: U. Beck ( Risk Society, 1992) et A. Giddens (The consequences of the modernity, 1990). Un troisieme auteur ayant un statut secondaire et simplement accessoire dans le travail, N. Luhmann, a egalement ete evoque de facon indirecte pour completer notre reflexion mais aussi pour ouvrir de nouvelles pistes de recherche. Pourquoi reflechir en termes de "seconde modernite"? Parce que depuis les annees 70, se sont mises en place une serie de transformations dans les societes modernes avancees. (Abstract shortened by UMI.)
Les représentations des enseignants de leurs compétences professionnelles en comparaison avec les typologies de Perrenoud et Gauthier
Creators: name: Davidson, Ann-Louise
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Education, Administration.

description: Nombreux écrits traitant des changements en cours dans le monde éducatif de part et d'autre de l'occident, ont permis de repérer les diktats de mode qui permettent l'amélioration de l'enseignement. Le contexte ontarien, influence par ces tendances mondiales aussi américaines qu'européennes, possède une histoire riche de restructurations qui ont influencé la réforme qui est en oeuvre présentement. Par une analyse des représentations des enseignantes et des enseignants de leurs compétences professionnelles en commparaison avec les typologies de Perrenoud et de Gauthier, le présent projet s'attache à comprendre d'une part pourquoi ces derniers vivent l'exigence de perfectionnement professionnel impose par l'Ordre des enseignantes et des enseignants de l'Ontario avec tant de frustration et d'insatisfaction. D'autre part, ce projet vise à découvrir dans quelle mesure, il y a des écarts entre les représentations des enseignants, les définitions de l'Ordre des enseignantes et des enseignants de l'Ontario et les avancées des chercheurs face aux compétences professionnelles.
FINANCIAL MODEL OF A REGIONAL SOCIAL SPHERE DEVELOPMENT
Creators: name: Vladimir A. Artemov, Larisa V. Davydova
Publisher: name: TuEngr Group
Year: 2019
Subjects: Social investments
Social development
Financing regression model
Public finance management
Social financial influence
Public-private partnership (PPP).

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 13, 10A13B: 1-15
The Roles of CG31221, Shn, and Pura During Coxiella burnetii Infections
Creators: name: Hollenberg, Benjamin M.
Publisher: name: Washington State University
Year: 2022
Subjects: Coxiella burnetii
Molecular Biology

description: To investigate whether pura is helping Coxiella invade the cells, an experiment was run to analyze the amount of Coxiella outside of the cells. This experiment found that the pura gene had no effect on the amount of bacterial concentration outside of the cell. This information, combined with the knowledge that the pura gene does increase bacterial concentration in totality, suggests that pura could be important for Coxiella vacuole formation, since the pura didn’t increase bacterial concentration outside of the cell as we would expect from our previous data.
description: Finally, the Coxiella bacterial concentration in male and female flies of the same genetic line were analyzed, and showed the female flies have less Coxiella in them than male lines, suggesting that female flies have a stronger immune response to Coxiella.
description: All of this information can be used to help us gain a better understanding of Coxiella and its relationship to the innate immune system. By learning more about how our Drosophila model organism fights Coxiella, we can learn more about how to fight it in human populations, knowledge that could potentially save lives.
Competing risks of mortality by PAM50 intrinsic subtype of British Columbia tamoxifen-treated cohort of post-menopausal breast cancer patients
Creators: name: Chapman, Judith-Anne W.
name: Liu, Shuzhen
name: Leung, Samuel
name: Nielsen, Torsten
Publisher: name: Elsevier
Year: 2022

description: Background: PAM50 intrinsic subtypes have been shown to impact breast cancer prognosis. Methods: A British Columbia cohort of 718 post-menopausal women treated with tamoxifen, without chemotherapy, had tumours intrinsic-subtyped (Luminal A;Luminal B;Basal;HER2) and centrally-reviewed by immunohistochemical (IHC) for estrogen and progesterone receptor (ER and PgR). We tested whether intrinsic subtype and other patient and tumour characteristics were associated with type of death. Results: At median 11.7 years follow-up, 429 of 718 (60%) women died: 30% of deaths were breast cancer-specific (BrCa); 30%, other type (OT). In 425 women <70 years, 32% died of BrCa and 19% of OT. In 293 >70, 27% died of BrCa and 45% of OT. Intrinsic subtype was associated with BrCa (p=0.001); and older age, with OT (p<0.001). Additionally, step-wise cause-specific models indicated larger tumour size (p<0.001), more positive lymph nodes (p<0.001), and less PgR stain (p=0.03) were associated with worse BrCa survival; more positive lymph nodes (p=0.002) and lymphovascular invasion (p=0.02) were associated with worse OT. Adjusted BrCa and OT survival is provided by factor at 5-, 10-, and 15-years. Conclusions: Intrinsic subtype was associated with BrCa death while age was associated with OT, the majority of deaths in women >70 being from OT.
Analysis of toroidal shells using the semi-analytical DQM.
Creators: name: Jiang, Wen.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Engineering, Mechanical.

description: The present thesis consists of two main parts. The first part is concerned with the vibration and statics of transversely isotropic thick-walled toroidal shells. The second part is concerned with the vibration and statics of orthotropic thin-walled toroidal shells. In the first part a solution based on the linear three-dimensional theory of elasticity is developed for vibration and static problems of toroidal shells. The theory is developed for transversely isotropic toroids of arbitrary but uniform thickness. In the semi-analytical method that is adopted Fourier series are written in the circumferential direction, forming a set of two-dimensional problems. Finally results are determined for local surface loading problems. In the second part a solution based on the linear elastic Sanders-Budiansky shell equations is developed. The vibration and static characteristics of orthotropic toroidal shells of variable thickness are considered. A semi-analytical method in which Fourier series are written in the circumferential direction is adopted, forming a set of one-dimensional problems. A novelty in the solution concerns the use of power series as trial functions in a domain exhibiting cyclic periodicity. Results are determined in the second part for two separate applications. The problems in both parts of the work are solved using the differential quadrature method. A commercial finite element program is used to determine alternative solutions. The results from these two methods are compared, and conclusions are drawn.
Journal of Applied Hermeneutics, 2017
Creators: name: Journal Of Applied Hermeneutics
Publisher: name: Journal of Applied Hermeneutics
Year: 2017

description: Grieving as Limit Situation of Memory: Gadamer, Beamer, and Moules on the Infinite Task Posed by the Dead
And Coyote Howled: Listening to the Call of Interpretive Inquiry
Grief and Hermeneutics: Archives of Lives and the Conflicted Character of Grief
Education and the Formative Power of Hermeneutic Practice
Self-transformation: Body, Mind, and Spirit
Conducting Hermeneutic Research in International Settings: Philosophical, Practical, and Ethical Considerations
Losing the So-Called Paradigm War: Does our Confusion, Disarray, and Retreat Contribute to the Advance?
Changing the Shape of Sickle Cell Disease Treatment: A Hermeneutic Study of a Case that Changed a Family and a Medical Practice
Deconstructing the Phenomenon of Apology
A Hermeneutic Phenomenology: The Death of the Other Understood as Event
Thoughts on the Return of Yesterday's War
Is it Really “Yesterday’s War”? What Gadamer Has to Say About What Gets Counted
ASSESSMENT AND OPTIMIZATION OF PREGNANCY AND CHILDBIRTH IN WOMEN OF ADVANCED REPRODUCTIVE AGE
Creators: name: Gulammakhmudova, D.V.
name: Nazarova, S.T.
Publisher: name: Zenodo
Year: 2025

description: Advanced reproductive age is typically defined as the period after 35 years old when a woman becomes pregnant. In recent decades, there has been a growing trend of increasing maternal age due to social, environmental, and medical factors. According to Cleary-Goldman et al. (2005), pregnancies in women over 35 are associated with a significantly increased risk of obstetric complications such as gestational diabetes, hypertension, and chromosomal abnormalities. Furthermore, Schimmel et al. (2006) report that maternal age influences both maternal and neonatal outcomes, making age a critical factor in pregnancy management.
Clover Report, Spring 2023
Creators: name: Washington State University Skamania County Extension
Publisher: name: Washington State University
Year: 2023
Subjects: 4-H Club
Animal Husbandry

description: Newsletter issue includes: Leader's Council; Quilt squares needed; Monday Deadline; Horse events; Swine Weigh In; Horse Certificates; Registering for Fair; Ducks; Poster Making Kits Available Soon!
Reduced main group compounds: Stannides and phosphides.
Creators: name: Guérin, Frédéric.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Chemistry, Inorganic.

description: The intermetallic phase, Na$\sb4$Sn, can be synthesised by a solid state reaction starting from stoichiometric quantities of the elements. It crystallizes in the orthorhombic space group Pnam with 4 asymmetric units per unit cell (a = 9.744(3)A, b = 22.751(10)A, c = 5,5390(15)A). The reactivity of Na$\sb4$Sn with organic and inorganic halides, elements and organic cations was investigated. The interconversion between and $\rm P\sb{21}\sp{3-}$ and P$\sb \sp{2-}$ has been demonstrated. Coordinating solvents, such as THF and pyridine, stabilise the more reduced P$\sb{21}\sp{3-}$ while the less reduced P$\sb \sp{2-}$ is favored when a non-coordinating solvent like EtOH is used. The reaction of P$\sb{21}\sp{3-}$ with Bu$\sb3$SnCl yields the new polyphosphides P$\sb \sp{2-}.$ The structure of this new anion was deduced from $\sp{31}$p studies.
Critique et totalité : le sens de l'altérité chez Jürgen Habermas.
Creators: name: Savidan, Patrick.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Philosophy.

description: Le dogmatisme, entendu comme fermeture du discours theorique sur soi, est le risque central que courent ces pensees qui ne se resolvent pas a l'abandon de tout projet d'emancipation. La philosophie politique et sociale contemporaine semble d'ailleurs, legitimement, si preoccupee par ce risque que, le plus souvent, elle se detourne, ni plus ni moins, de la question meme du politique, des lors que l'on concoit celle-ci a l'echelle de la societe entiere. Cette etude se propose de demontrer que la theorie habermassienne de l'agir communicationnel peut ouvrir une voie vers une conciliation de l'exigence critique et du point de vue totaliste que requiert le discours politique. Cette conciliation prend la forme, chez Jurgen Habermas, d'une totalite radicalement ouverte. C'est ce que nous tentons de demontrer en proposant une reevaluation, a partir de l'oeuvre tardive de Theodor Adorno, de la notion de mimesis. Avec la critique communicationnelle, Jurgen Habermas reactive le rapport de l'alterite a l'identite et maintient, par la tension des deux termes, la possibilite du politique et le deploiement radical de la pensee critique.
Benchmark aluminum alloy solidification experiments in microgravity and on Earth
Creators: name: Williams, Thomas J
Publisher: name: University of Iowa
Year: 2022
Subjects: Aluminum
Columnar to Equiaxed Transition
Melt Convection
Microgravity
Solidification
public abstract
Heat Transfer

description: Modeling the physical phenomena that occur during the solidification of metal alloys is a key interest for industry and an ongoing challenge. Gravity driven processes such as melt convection and the transport of buoyant solid strongly affect macrosegregation within a casting as well as the final grain structure, including the columnar to equiaxed transition (CET). Benchmark solidification data is necessary to validate numerical models that predict transport within the molten metal. Cylindrical samples of Al-4, 10, and 18 wt.% Cu as well as Al-7 wt.% Si, all without grain refiner, are solidified in a bottom-up manner in terrestrial and microgravity environments. The Al-Cu alloys have primary solids that are negatively, neutrally, and positively buoyant in their melt. The different relative densities in each alloy results in differing gravity driven transport of free primary solid. The Al-Si alloy is used in an attempt to initiate CET without the addition of grain refiner and to relate the present experiments to other similar experiments on a similar subject. However, the grain structures of the Al-Si specimens were entirely columnar, indicating either grain refiner or different solidification parameters are necessary to observe CET in this alloy. Significant differences are observed between the grain structures of the microgravity and terrestrial Al-Cu samples. All of the samples solidified in microgravity exhibit solely equiaxed grains while the corresponding terrestrial specimens all exhibit a CET. The presence of columnar grains in the terrestrial samples contrasted with their absence in the microgravity samples suggests the presence of melt convection in all terrestrial samples. The Al-4 and 18% Cu samples show evidence of grain sedimentation and floatation respectively. Both eutectic distribution and solute concentration indicate the presence of inverse segregation within all Al-Cu samples. The eutectic and solute measurements generally correspond well with each other. All terrestrially solidified samples exhibit areas of high eutectic fraction and solute concentration that further suggest the presence of melt convection during solidification. The results from these experiments, including temperatures, grain structure, eutectic fraction, and macrosegregation, are presented as benchmark data for validation of future numerical modeling efforts. Heat flux boundary conditions on the samples are determined and provided. Thermal characterization is accomplished by calculating and presenting process parameters on each sample.
Eye movement desensitisation reprocessing for children in Singapore
Creators: name: Lee-Lek, Yvonne Siew Ling
Publisher: name: Swinburne
Year: 2024

description: This research identified four treatment goals for the treatment of complex trauma in children, aged six to twelve, in Singapore. Eye Movement Desensitization Reprocessing (EMDR) was identified as a promising treatment model in addressing these four goals. Two studies, a retrospective case study and a clinical trial, were undertaken to create a developmentally appropriate modified EMDR protocol relevant to the complex trauma treatment landscape in Singapore. Results from the clinical trial suggest that this modified protocol is efficacious and efficient in treating complex trauma, and bolsters resiliency in children who face further traumatic exposure.
Toxicokinetics and fate of alpha-terthienyl, a botanical larvicide.
Creators: name: Szenasy, Erica.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1995
Subjects: subject: Biology, Ecology.

description: The fate of the phototoxic phytochemical, $\alpha$-terthienyl ($\alpha$-T), which has been proposed as a novel mosquito larvicide was studied in target and non-target organisms. The lethality of this compound was determined in the laboratory by uniform acute toxicity bioassays using the target mosquito larvae, Aedes atropalpus, and two non-target species. Daphnia magna represented a potentially sensitive non-target organism and Limnephilus indivisus (caddisfly) larvae represented a potentially insensitive non-target species. The mosquito larvae had a lethal concentration for 50% mortality (LC$\sb{50})$ value determined to be 31.97 ppb. However, D. magna showed an order of magnitude more sensitivity towards $\alpha$-T with an LC$\sb{50}$ of 1.74 ppb while L. indivisus larvae showed considerably less sensitivity at 64.76 ppb. The bioaccumulation potential was investigated in the three species by toxicokinetic studies. Initial rates of accumulation by the first compartment were highest for A. atropalpus, followed by D. magna and L. indivisus. A. atropalpus reached a steady state in the second compartment. The accumulation of radiolabeled ($\sp3$H) $\alpha$-T did not plateau in the non-target species. The clearance rate constants were highest for D. magna and lowest for L. indivisus, indicating that the most sensitive species was eliminating $\alpha$-T the fastest, in contrast with previous studies. The results from the above studies, combined with previous field trials, predicted mortality at the applied concentrations. This did not translate into severe impacts in the fate study under natural conditions, probably due to volatilization, presence of dissolved organic matter in the water, and rapid photodegradation of $\alpha$-T. In addition, the microcosms were highly anoxic relative to the natural pools. (Abstract shortened by UMI.)