cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Ectonocryptoides quadrimeropus Shelley & Mercurio 2005
Creators: name: Shelley, Rowland M.
name: Mercurio, Randy
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Chilopoda
Scolopendromorpha
Scolopocryptopidae
Ectonocryptoides
Ectonocryptoides quadrimeropus

description: Ectonocryptoides quadrimeropus Shelley & Mercurio, 2005
Ectonocryptoides quadrimeropus Shelley & Mercurio, 2005:34 –38, figs. 1–16.
Type specimens. Two syntypes (AMNH) collected by R.T. Schuh and B.M. Massie, 4–7 April 1985, at the Universidad National Autonoma de Mexico Field Station at Chamela, Jaliso, Mexico. The site is approximately 59 km (36.9 mi) N Barra de Navidad on Highway 200, the coastal highway.
Diagnosis. With the characters of the genus.
Habitat. The syntypes and only known specimens were recovered from a berlesate of subtropical thorn forest litter at roughly 30 m (98 ft) elevation.
Distribution. Known only from the type locality.
description: Published as part of Shelley, Rowland M. & Mercurio, Randy, 2008, Redescription and illustrations of the Centipede, Ectonocryptops kraepelini Crabill, 1977 (Scolopendromorpha: Scolopocryptopidae: Ectonocryptopinae), pp. 65-68 in Zootaxa 1824 on page 68, DOI: 10.5281/zenodo.183065
title: Στάσεις και αντιλήψεις των πολιτών σχετικά με τη κλιματική αλλαγή και ενεργειακή κρίση
title: Citizens' attitudes and perceptions on climate change and energy crisis
titleType: AlternativeTitle
Creators: name: Βασιλείου, Αναστάσιος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2024
Subjects: subject: Κλιματική αλλαγή
subject: Ενεργειακή κρίση
subject: Αέρια του θερμοκηπίου
subject: Ανανεώσιμες πηγές ενέργειας
subject: Ορυκτά καύσιμα
subject: Υπερθέρμανση του πλανήτη
subject: Τήξη πάγων
subject: Ενεργειακή αποδοτικότητα
subject: Βιώσιμη ανάπτυξη
subject: Συμφωνία του Παρισιού

description: Η εργασία επικεντρώνεται στις απόψεις των Ελλήνων σχετικά με την κλιματική αλλαγή και την ενεργειακή κρίση, δύο από τις σημαντικότερες προκλήσεις της εποχής μας. Η κλιματική αλλαγή, που οφείλεται κυρίως στην ανθρώπινη δραστηριότητα, οδηγεί σε ακραία καιρικά φαινόμενα, άνοδο της θερμοκρασίας και σημαντικές περιβαλλοντικές καταστροφές. Από την άλλη, η ενεργειακή κρίση προκύπτει από την υπερβολική εξάρτηση από τα ορυκτά καύσιμα και την εξάντληση των φυσικών πόρων, γεγονός που αναδεικνύει την ανάγκη για ανανεώσιμες πηγές ενέργειας. Οι Έλληνες αντιλαμβάνονται την κλιματική αλλαγή ως σοβαρό πρόβλημα και εκφράζουν τη στήριξή τους σε πολιτικές για την αντιμετώπισή της. Παράλληλα, η ενεργειακή κρίση προκαλεί ανησυχία, κυρίως λόγω του κόστους και των γεωπολιτικών συνεπειών, ωθώντας τη χώρα να στραφεί σε βιώσιμες λύσεις. Η εργασία αναλύει, επίσης, πώς οι δύο αυτές κρίσεις συνδέονται, τονίζοντας την ανάγκη για δράση σε παγκόσμιο επίπεδο.
Additional file 5: of Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection
Creators: name: Tamsyn Derrick
name: Last, Anna
name: Burr, Sarah
name: Roberts, Chrissy
name: Nabicassa, Meno
name: Cassama, Eunice
name: Bailey, Robin
name: Mabey, David
name: Burton, Matthew
name: Holland, Martin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Computational Biology

description: Relative abundance of miR in the conjunctiva of cases of follicular trachoma (TF) and controls (N). MiR with a mean read count in TF cases or controlsâ
Nudochernes Beier 1935
Creators: name: Xu, Hongru
name: Gao, Zhizhong
name: Zhang, Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Pseudoscorpiones
Chernetidae
Nudochernes

description: Genus Nudochernes Beier, 1935
Nudochernes Beier, 1935: 122; Beier, 1959: 48; Harvey, 1991: 607.
Type species: Nudochernes montanus Beier, 1935, by original designation.
Key to the Chinese species of Nudochernes
1. Pedipalpal femur 3.20 times longer than broad............................................ N. lipsae Mahnert, 2003
- Pedipalpal femur 2.40–2.90 times longer than broad.......................................................... 2
2. Trichobothria st closer to t than to sb; pedipalpal chela (with pedicel) 3.40–3.80 times longer than broad............................................................................................... N. troglobius Mahnert, 2009
- Trichobothria s t situated midway between sb and t; pedipalp chela (with pedicel) 3.10 (♂) 2.62–2.68 (♀) times longer than broad........................................................................ .. N. pseudptroglobius sp. nov.
description: Published as part of Xu, Hongru, Gao, Zhizhong & Zhang, Feng, 2022, Two new species of the pseudoscorpion subfamily Lamprochernetinae Beier, 1932 from Guizhou, China (Pseudoscorpiones: Chernetidae), pp. 581-592 in Zootaxa 5105 (4) on pages 582-587, DOI: 10.11646/zootaxa.5105.4.7, http://zenodo.org/record/6333898
Οι εκπαιδευτικές καινοτομίες στο Νηπιαγωγείο: Η αξιοποίηση του διαδραστικού πίνακα.
Creators: name: Μάρκου, Κλεοπάτρα
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2024
Subjects: subject: Εκπαίδευση, Προσχολική -- Ελλάδα
subject: Εκπαιδευτικές καινοτομίες -- Ελλάδα
subject: Εκπαιδευτική τεχνολογία -- Ελλάδα
subject: Εκπαίδευση -- Επίδραση των τεχνολογικών καινοτομιών στην -- Ελλάδα
subject: Εκπαιδευτική αλλαγή -- Ελλάδα
subject: Διαδραστικός πίνακας
subject: Εκπαιδευτικές καινοτομίες
subject: Καινοτομίες
subject: Καινοτομίες στο νηπιαγωγείο
subject: Εκπαιδευτικές καινοτομίες στο νηπιαγωγείο

description: Αριθμός Εισαγωγής: 013946 cd
description: Η παρούσα διπλωματική εργασία εξετάζει τις απόψεις των νηπιαγωγών για τις εκπαιδευτικές καινοτομίες με έμφαση στην υιοθέτηση καινοτόμων τεχνολογιών, όπως ο διαδραστικός πίνακας στο νηπιαγωγείο. Μέσα από τη μελέτη των απόψεων των νηπιαγωγών, διερευνώνται τα οφέλη που προκύπτουν από την εφαρμογή καινοτομιών στην καθημερινή εκπαιδευτική πρακτική, καθώς και οι δυσκολίες ή εμπόδια που περιορίζουν την υιοθέτησή τους. Ιδιαίτερη έμφαση δίνεται στην αξιολόγηση της συμβολής του διαδραστικού πίνακα, στη συχνότητα και το είδος της χρήσης του μέσα στην τάξη του νηπιαγωγείου σήμερα καθώς και στις εκτιμήσεις των νηπιαγωγών για τις μελλοντικές τεχνολογικές εκπαιδευτικές καινοτομίες.
N-acetyl-b-D-glucosaminidase: A potential cardiorenal biomarker with a relevant impact on ICD shock therapies and mortality
Creators: name: Allgaier, Raphael
name: Strack, Christina
name: Wallner, Stefan
name: Hubauer, Ute
name: Uecer, Ekrem
name: Lehn, Petra
name: Keyser, Andreas
name: Luchner, Andreas
name: Maier, Lars
name: Jungbauer, Carsten
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: SUDDEN CARDIAC DEATH; KIDNEY INJURY MOLECULE-1; BETA-D-GLUCOSAMINIDASE; HEART-FAILURE; RISK STRATIFICATION; TUBULAR DAMAGE; VENTRICULAR-ARRHYTHMIAS; ESC GUIDELINES; TASK-FORCE; ASSOCIATION; cardiorenal syndrome; ICD shock therapies; tubular markers
subject: 610 Medizin

description: Aims Chronic heart failure may lead to chronic kidney disease. Previous studies suggest tubular markers N-acetyl-b-D-glucosaminidase (NAG) and Kidney-injury-molecule-1 (KIM-1) as potential markers for the cardiorenal syndrome (CRS). The prognostic value of NAG and KIM-1 regarding implantable cardioverter defibrillator (ICD) shock therapies is unknown. Methods We included 314 patients with an ICD and collected plasma and urine samples. Urine-values of NAG and KIM-1 got related to urinary creatinine. Outcomes of interest were sustained adequate shock therapies and a combined endpoint of all-cause mortality, rehospitalisation due to congestive heart failure and adequate shock therapies. Follow up time was 32 months (IQR 6-35 months). Results KIM-1 and NAG were positively correlated with NT-proBNP (KIM-1:r= .34,P < .001; NAG:r= .47,P < .001). NAG was significantly elevated in patients with primary prevention compared with secondary prevention ICD indication (P= .003). According to Kaplan Meier analysis, NAG as well as NT-proBNP were significant predictors for adequate ICD shock therapies and for the combined endpoint (eachP < .001). Elevated KIM-1 showed no significant differences (eachP= n.s.). In multivariate cox regression analysis, NAG as well as NT-proBNP were both independent predictors for adequate ICD shock therapies as well as the combined endpoint, beside ejection fraction <35% (eachP < .05). Diabetes, primary prevention ICD indication, coronary artery disease, eGFR and age were no significant predictors for both endpoints (eachP= n.s.). Conclusion Similar to NT-proBNP, NAG showed promising value for overall prognostication in ICD patients. Especially, NAG seems to incorporate an additional prognostic value regarding occurrence of ICD shock therapies.
Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease
Creators: name: Haberl, Elisabeth M.
name: Pohl, Rebekka
name: Rein-Fischboeck, Lisa
name: Höring, Marcus
name: Krautbauer, Sabrina
name: Liebisch, Gerhard
name: Buechler, Christa
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: HIGH-THROUGHPUT QUANTIFICATION; INSULIN-RESISTANCE; MOUSE MODEL; PHOSPHATIDYLCHOLINE; STEATOHEPATITIS; HOMEOSTASIS; STEATOSIS; CERAMIDE; DIETHYLNITROSAMINE; INFLAMMATION; Liver tumor; Ceramide; Phospholipids; Lipogenesis; Cholesterol; Diethylnitrosamine
subject: 610 Medizin

description: Background Emerging data support a role for lipids in non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC) in humans. With experimental models such data can be challenged or validated. Mice fed a low-methionine, choline-deficient (LMCD) diet develop NASH and, when injected with diethylnitrosamine (DEN), HCC. Here, lipidomic analysis was used to elucidate whether the NASH and HCC associated lipid derangements resemble the lipid profile of the human disease. Methods Lipids were measured in the liver of mice fed a control or a LMCD diet for 16 weeks. DEN was injected at young age to initiate hepatocarcinogenesis. DEN treatment associated changes of the lipid composition and the tumor lipidome were evaluated. Results LMCD diet fed mice accumulated ceramides and triacylglycerols in the liver. Phospholipids enriched with monounsaturated fatty acids were also increased, whereas hepatic cholesterol levels remained unchanged in the LMCD model. Phosphatidylcholine and lysophosphatidylcholine concentrations declined in the liver of LMCD diet fed mice. The changes of most lipids associated with LMCD diet feeding were similar between water and DEN injected mice. Several polyunsaturated (PU) diacylglycerol species were already low in the liver of DEN injected mice fed the control diet. Tumors developed in the liver of LMCD diet fed mice injected with DEN. The tumor specific lipid profile, however, did not resemble the decrease of ceramides and PU phospholipids, which was consistently described in human HCC. Triacylglycerols declined in the cancer tissues, which is in accordance with a low expression of lipogenic enzymes in the tumors. Conclusions The LMCD model is suitable to study NASH associated lipid reprogramming. Hepatic lipid profile was modestly modified in the DEN injected mice suggesting a function of these derangements in carcinogenesis. Lipid composition of liver tumors did not resemble the human HCC lipidome, and most notably, lipogenesis and triacylglycerol levels were suppressed.
Tingis denudata HORVATH 1906
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Tingis
Tingis denudata

description: Tingis denudata HORVÁTH, 1906
E S P S p a n i e n: Kanarische Inseln, Tenerife, San Andres, 1 Ex., 15. III. 1979, leg. HE.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 124, DOI: 10.5281/zenodo.7507194
Antiinfektive Therapie: Therapiestrategien bei Sepsis und septischem Schock
Creators: name: Hanses, Frank
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: Prognose der Sepsis · Antibiotika · Antimykotika · Kombinationstherapie · Mikrobielle Antibiotikaresistenz
subject: 610 Medizin

description: Sepsis und septischer Schock sind weiter mit einer hohen Mortalität und Morbidität verbunden. Ein entscheidender Faktor für die Verbesserung des Outcomes ist die schnelle Einleitung einer wirksamen Antibiotikatherapie. Das frühe Erkennen einer Sepsis innerhalb der ersten Stunde stellt dabei eine der größten Herausforderungen dar. Zu einer wirksamen empirischen Therapie gehören gezielt ausgewählte Breitspektrumantibiotika, in speziellen Situationen auch Kombinationstherapien bzw. Antimykotika. Deeskalationsstrategien zur Verschmälerung bzw. Verkürzung der Therapie sind sicher und können Nebenwirkungen begrenzen.
Programming structural-colour modulation range of elastomer enables information storage
Creators: name: Zhuang, Yingying
name: Liu, Xuan
name: Hu, Honglong
name: Zheng, Zhigang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Cholesteric liquid crystal elastomers (CLCEs) has garnered significant attention in the field of information display and storage. Obtaining multiple structural colours in a single elastomer film is highly desirable but presents a considerable challenge. Here, we have successfully achieved manipulable range of structural colours in a CLCE film by ingeniously introducing the photopolymerisation during thiol-acrylate reaction process. This particular strategy involves triggering spatial shrinkage of the polymer network in a pre-designed region following solvent evaporation, resulting in a blue shift of the structural colour compared to the background. Consequently, we can construct multi-colour and multi-pattern elastomer films by precisely controlling the localised polymerisation. Notably, these patterns can be concealed in a reversible manner as the film undergoes a specific degree of elongation and can be restored when external force is removed. This work demonstrates a straightforward method of programming structural-colour modulation range, eliminating the need for material changes or intricate preparation processes, broadening the applications of stretchable elastomers in information storage, encryption, anti-counterfeiting, and dynamic photonics.
Megachernes Beier 1932
Creators: name: Xu, Hongru
name: Gao, Zhizhong
name: Zhang, Feng
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Pseudoscorpiones
Chernetidae
Megachernes

description: Genus Megachernes Beier, 1932
Megachernes Beier, 1932: 128; Beier, 1933: 518; Beier, 1948: 476; Morikawa, 1960: 144; Harvey, 1991: 599.
Type species: Chernes grandis Beier, 1930, by original designation.
Key to the Chinese species of Megachernes
1. Leg IV femur + patella with numerous glandular microsetae........................... M. glandulosus Mahnert, 2009
- Leg IV femur + patella without glandular microsetae......................................................... 2
2. Male pedipalpal patella with hump................................................. M. tuberosus Mahnert, 2009
- Male pedipalpal patella without hump..................................................................... 3
3. Pedipalpal femur less than 4.00 times longer than board....................................................... 4
- Pedipalpal femur more than 4.00 times longer than board..................................... M. titanius Beier, 1951
4. Leg IV femur + patella more than 4.00 times longer than deep.................................................. 5
- Leg IV femur + patella less than 4.00 times longer than deep................................................... 6
5. Movable chelal finger with 9 retrolateral accessory teeth; all blades of rallum smooth..... M. himalayensis (Ellingsen, 1914)
- Movable chelal finger with 21 retrolateral accessory teeth; only distal blade of rallum denticulate.................................................................................................... M. vietnamensis Beier, 1967
6. Only distal blade of rallum denticulate; st situated closer to t than to sb ........................ M. grandis (Beier, 1930)
- All blades of rallum denticulate; st situated closer to sb than to t ................................ M. biyunensis sp. nov.
description: Published as part of Xu, Hongru, Gao, Zhizhong & Zhang, Feng, 2022, Two new species of the pseudoscorpion subfamily Lamprochernetinae Beier, 1932 from Guizhou, China (Pseudoscorpiones: Chernetidae), pp. 581-592 in Zootaxa 5105 (4) on pages 587-591, DOI: 10.11646/zootaxa.5105.4.7, http://zenodo.org/record/6333898
Molecular curvature and the twist-bend liquid crystal phases: the effect of the spacer
Creators: name: Gibb, Calum J.
name: Storey, John M. D.
name: Imrie, Corrie T.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy

description: The synthesis and characterisation of ten members of the 4[{[4({5[4((4-cyanophenyl)phenyl]oxy)pentoxy}yl)phenyl]methylidene}amino] phenyl 4-alkyloxybenzoates is presented. These dimers are referred to using the acronym CBO5OIBeOm in which m refers to the number of carbon atoms in the terminal chain and varies from 1 to 10. The CBO5OIBeOm series exhibits nematic (N), twist-bend nematic (NTB), and smectic A (SmA) phases depending on the length of the terminal chain. Although the NTB phase is observed, these dimers do not exhibit the twist-bend smectic C (SmCTB) phases. By comparison, the structurally similar CB6OIBeOm series does exhibit the SmCTB phases, and this strongly suggests that the formation of the SmCTB phase is more sensitive to molecular curvature than that of the NTB phase.
Bibliographies of Translations in Four Slovak Periodicals: Aspekt (1993–2004), Kapitál (2017–2024), Revue svetovej literatúry (1995–2015), and Verzia (2020–2024)
Creators: name: Hostová, Ivana
name: Bachledová, Marianna
name: Gramanich Štromajer, Richard
name: Spišiaková, Eva
name: Tyšš Rondziková, Natália
name: Novotný, Róbert
Publisher: name: Zenodo
Year: 2024

description: The paper provides documentation on the bibliographic data sets of translations published in Slovak periodicals: Revue svetovej literatúry (1995–2015), Aspekt (1993–2004), Kapitál (2017–2024), and Verzia (2020–2024), assembled and processed in 2024 (Hostová et al., 2024a; Hostová et al., 2024b; Hostová et al., 2024c; Hostová et al., 2024d). It explains the categories used, the methodology employed, and briefly outlines the purpose of assembling these bibliographies and their potential applications in research.
Broadband reflection and infrared shielding characterisation of cholesteric liquid crystals doped with UV–absorbing layer
Creators: name: Zhong, Zhenlei
name: Zhao, Yuzhen
name: Li, Xun
name: He, Zemin
name: Gao, Hong
name: Guo, Zhun
name: Wang, Dong
name: Wang, Lei
name: Luan, Yi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Cancer

description: Cholesteric liquid crystals (CLCs) are widely used in the field of infrared (IR) modulation as a chiral photonic material with wavelength and polarisation selective reflection. However, there is ongoing interest in discovering a simpler method to harness liquid crystal materials for IR shielding. In this study, a CLC-based IR reflector was prepared. Broadband reflection of CLC was achieved by spin-coating a layer of PMMA-UV8080 to generate a vertical intensity gradient of UV light. By optimising the concentration of the UV absorber, UV intensity, and temperature during the polymerisation process, the reflective bandwidth in the NIR band at 1656 nm is 554 nm. It was found that the temperature difference between the CLC reflector covered with 3% R811 and covered with a blank liquid crystal cassette under IR light irradiation was 5.7 °C. Additionally, the temperature difference between the surface of the blank liquid crystal cell and the CLC reflector under IR thermography after irradiation for 40 min under an IR therapeutic apparatus was 3 °C. Furthermore, the UV shielding efficiency of the prepared CLC reflector reached 99.2%. Both these findings, coupled with the simplicity of the preparation, suggest that the prepared CLC reflectors hold great promise for future applications.
Biological effects of a new ultraviolet A1 prototype based on light‐emitting diodes on the treatment of localized scleroderma
Creators: name: Arndt, Stephanie
name: Lissner, Clara
name: Unger, Petra
name: Bäumler, Wolfgang
name: Berneburg, Mark
name: Karrer, Sigrid
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: GROWTH-FACTOR-BETA; HUMAN DERMAL FIBROBLASTS; BLEOMYCIN-INDUCED SCLERODERMA; UVA(1) RADIATION-THERAPY; SMOOTH MUSCLE ACTIN; A1 PHOTOTHERAPY; SINGLET OXYGEN; ANIMAL-MODEL; TGF-BETA; MATRIX METALLOPROTEINASE-1; extracellular matrix; fibroblasts; LED-based UVA(1); localized scleroderma; phototherapy
subject: 610 Medizin

description: Ultraviolet A(1)(UVA(1)) phototherapy (spectral range 340-400 nm) is a well-established treatment option for various skin diseases such as localized scleroderma. Recent improvements of conventional UVA(1)light sources (metal-halide or fluorescent lamps) have brought attention to a new light-emitting diode (LED) technology with remarkable advantages in handling and clinical routine. This study provides a preclinical histological and molecular evaluation of an LED-based UVA(1)prototype with a narrower spectral range (360-400 nm) for treating localized scleroderma. Scleroderma mouse models and fibroblasts in vitro were exposed to LED-based UVA(1)phototherapy or to irradiation with a commercially available metal-halide lamp emitting low-dose (20, 40 J/cm(2)), medium-dose (60 J/cm(2)) and high-dose (80, 100 J/cm(2)) UVA(1)light. Both UVA(1)light sources affected inflammatory genes (IL-1 alpha and IL-6) and growth factors (TGFss-1 and TGFss-2). Increased collagen type 1 was reduced after UVA(1)phototherapy. Matrix metalloproteinase-1 was more enhanced after a medium dose of LED-based UVA(1)phototherapy than after conventional treatment. In vivo, dermal thickness and the amount of collagen were reduced after both treatment methods. Remarkably, myofibroblasts were more effectively reduced by a medium dose of LED-based UVA(1)phototherapy. The study indicates that LED-based UVA(1)phototherapy yields similar or even better results than conventional treatment. In terms of biosafety and patient comfort, LED-based UVA(1)phototherapy offers clear advantages over conventional treatment because of the use of a narrower and less harmful UVA(1)spectrum, less heat generation and shorter treatment times at the same irradiation intensity. Clinical studies are required to confirm these results in patients with localized scleroderma.
Study on the application and performance of liquid crystal emulsion system in sunscreen products
Creators: name: Feng, Bei
name: Shang, Yazhuo
name: Li, Cheng Liang
name: Ye, Zhicheng
name: Liu, Honglai
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Information Systems not elsewhere classified
subject: Developmental Biology

description: Liquid crystal (LC) emulsion is a new emulsion system which has excellent application potential in the field of cosmetics. In this study, the LC emulsifier and traditional emulsifier were used to prepare the emulsions containing different types of sunscreen agents, respectively. The microstructure, sunscreen performance and rheological properties of the emulsions were studied systematically. The results showed that the formation of LC structure was not affected by sunscreen agents. LC structure can also enhance the sunscreen property of the emulsion as well as improve the sensory property. Further, we combined different sunscreen agents to prepare LC sunscreen emulsion. The sunscreen performance and repair effectiveness of emulsion were evaluated by human test. The results showed that LC sunscreen emulsion has an increased SPF value from 56 to 70 compared to non-LC sunscreen emulsion. Meanwhile, the LC structure also enhanced the moisturising properties of the emulsion, and the TEWL value of LC emulsion and non-LC emulsion was 67.4% and 96.5%, respectively. In addition, LC sunscreen emulsion has higher safety and better storage stability. In conclusion, this study provided the practical application of LC emulsion systems as well as the important guidance for developing excellent sunscreen emulsions.
Large-area preparation of rainbow cholesteric liquid crystal polymer network films using a photoisomerizable chiral dopant
Creators: name: Li, Zongqi
name: Zhao, Jinghua
name: Wu, Limin
name: Li, Yi
name: Liu, Wei
name: Yang, Yonggang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Computational Biology

description: Since the cholesteric liquid crystal polymer network (CLCN) films with a structural colour have been applied for decoration, those with colourful patterns become more attractive. They have been successfully prepared using photochromic cholesteric liquid crystals with the addition of photoisomerizable chiral dopants. Herein, two isosorbide derivatives with benzoate and cinnamate groups were synthesised using isomannide through chirality inversion and without using protecting groups. CLCN films were prepared using these two isomers as the chiral dopants. The structural colour of the films can be tuned by the photoisomerisation of the chiral dopants. Colourful patterns were also prepared using photomasks, which were suitably applied for decoration and anti-counterfeiting. Although the isomer with a higher melting point tended to induce the crystallisation of the CLC mixtures, the CLC mixtures prepared using the isomer with a lower melting point were stable at room temperature. Rainbow CLCN films were prepared using photomasks on a coating line.
title: ÐÐ°ÐºÐ¾Ð½Ð¾Ð¼ÐµÑÐ½Ð¾ÑÑÐ¸ ÑÑÐµÐ½Ð¸Ñ Ð¸ Ð¸Ð·Ð½Ð°ÑÐ¸Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ ÐºÐ°ÑÐ±Ð¸Ð´Ð° Ð²Ð¾Ð»ÑÑÑÐ°Ð¼Ð° Ð´Ð»Ñ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸ÐµÐ²ÑÑ Ð±ÑÑÐ¸Ð»ÑÐ½ÑÑ ÑÑÑÐ±
title: ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÑ 2.5.3. Ð¢ÑÐµÐ½Ð¸Ðµ Ð¸ Ð¸Ð·Ð½Ð¾Ñ Ð² Ð¼Ð°ÑÐ¸Ð½Ð°Ñ
titleType: Subtitle
Creators: name: Ð¯ÑÐ¸Ð¼Ð¾Ð²Ð¸Ñ, ÐÐ°Ð»ÐµÑÐ¸Ð¹
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: ÐÑÑÐ¸Ð»ÑÐ½ÑÐµ ÑÑÑÐ±Ñ
ÐÐ¾Ð»ÑÑÑÐ°Ð¼
ÐÐµÑÐ°Ð»Ð»Ñ
ÑÐ²ÐµÑÐ´ÑÐµ Ð¿Ð¾ÐºÑÑÑÐ¸Ñ
Ð½Ð°Ð¿Ð»Ð°Ð²ÐºÐ¸

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÑÐµÐ½Ð¸Ñ Ð¸ Ð¸Ð·Ð½Ð°ÑÐ¸Ð²Ð°Ð½Ð¸Ñ ÑÐ²ÐµÑÐ´ÑÑ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹ Ð°Ð»ÑÐ¼Ð¸Ð½Ð¸ÐµÐ²ÑÑ Ð±ÑÑÐ¸Ð»ÑÐ½ÑÑ ÑÑÑÐ±. Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ñ Ð¼Ð°ÑÐµÐ¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¼Ð¾Ð´ÐµÐ»Ð¸, Ð¾Ð¿Ð¸ÑÑÐ²Ð°ÑÑÐ¸Ðµ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð¼ÐµÑÐ½Ð¾ÑÑÐ¸ ÑÑÐµÐ½Ð¸Ñ Ð¸ Ð¸Ð·Ð½Ð°ÑÐ¸Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹ Ð² Ð·Ð°Ð²Ð¸ÑÐ¸Ð¼Ð¾ÑÑÐ¸ Ð¾Ñ Ð¸Ñ ÑÐ¾Ð»ÑÐ¸Ð½Ñ Ð¸ ÐºÐ¾Ð½ÑÐµÐ½ÑÑÐ°ÑÐ¸Ð¸ Ð»ÐµÐ³Ð¸ÑÑÑÑÐ¸Ñ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð², Ð¿Ð¾Ð´ÑÐ²ÐµÑÐ¶Ð´ÐµÐ½Ð½ÑÐµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ°Ð¼Ð¸ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð½ÑÑ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ¾Ð². Ð¢Ð°ÐºÐ¶Ðµ Ð¿ÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¸Ð½ÑÑ Ð¸ÑÐ¿ÑÑÐ°Ð½Ð¸Ð¹ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹ â Ð½Ð° ÑÐºÐ¾ÑÐ¾ÑÑÑ ÐºÐ¾ÑÑÐ¾Ð·Ð¸Ð¸, Ð²ÐµÐ»Ð¸ÑÐ¸Ð½Ñ ÑÐ»ÐµÐºÑÑÐ¾ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð° Ð¸ Ð¼ÐµÑÐ°Ð½Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ¸, Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐ¸Ð¼Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÐ¾ÑÑÐ°Ð²Ð° Ð¸ ÑÑÑÑÐºÑÑÑÑ. ÐÐ¾ÐºÐ°Ð·Ð°Ð½Ñ ÐºÐ¾ÑÑÐµÐ»ÑÑÐ¸Ð¾Ð½Ð½ÑÐµ ÑÐ²ÑÐ·Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð½ÑÑ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸Ðº Ñ ÑÑÐ¸Ð±Ð¾ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¼Ð¸ ÑÐ°ÑÐ°ÐºÑÐµÑÐ¸ÑÑÐ¸ÐºÐ°Ð¼Ð¸ Ð¿Ð¾ÐºÑÑÑÐ¸Ð¹.
title: Εμβολιασμός ενάντια στην γρίπη του υγειονομικού προσωπικού και η ανάλυση των πεποιθήσεων τους σχετικά με τον αντιγριπικό εμβολιασμό στα νοσοκομεία. Μελέτη περίπτωσης : Γ.Ν.Α. Γεώργιος Γεννηματάς
title: Vaccination against influenza of health workers and analysis of their beliefs about the anti-influenza vaccination in hospitals. Case study : G.N.A. Georgios Gennimatas
titleType: AlternativeTitle
Creators: name: Καρατζάς, Δημήτριος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2024
Subjects: subject: Γ.Ν.Α. Γεώργιος Γεννηματάς
subject: Αντιγριπικός εμβολιασμός
subject: Πεποιθήσεις υγειονομικού προσωπικού
subject: Γρίπη
subject: Εμβολιαστική κάλυψη
subject: Υποχρεωτικός εμβολιασμός
subject: Κίνητρα για εμβολιασμό
subject: Εμβόλιο
subject: Ιός
subject: Ανοσία αγέλης

description: Ο χώρος της υγείας αποτελεί έναν τομέα, ο οποίος επιφυλάσσει πολλούς κινδύνους στους εργαζομένους. Πολλές θέσεις εργασίας θεωρούνται πως αποτελούν βαρέα και ανθυγιεινά και προκαλούν σημαντική επιβάρυνση στην υγειά των εργαζόμενων. Συγκεκριμένα μπορούν να εκτεθούν σε διάφορες μολυσματικές ασθένειες, να δεχθούν ραδιενέργεια από διάφορα διαγνωστικά μηχανήματα ή ακόμα και να εκτεθούν σε μολυσματικά υγρά από κάποια σύριγγά, η οποία δεν απορρίφθηκε σωστά. Ένας καλός τρόπος για να περιοριστεί ο κίνδυνος από τις μολυσματικές ασθένειες είναι η χορήγηση εμβολίων, εφόσον αυτά υπάρχουν. Για διάφορους ιούς ή βακτήρια κυκλοφορούν διάφορα εμβόλια τα όποια μπορούν να εμποδίσουν την διάδοσή των μολυσματικών ασθενειών στις δομές υγείας. Συμφώνα με τον WHO δίνεται ισχυρή σύσταση να πραγματοποιούνται εμβόλια για λοιμώδεις ασθένειες από όλους τους εργαζόμενους στις δομές υγείας. Στην παρούσα εργασία θα ασχοληθούμε με τον αντιγριπικό εμβολιασμό. Ο συγκεκριμένος εμβολιασμός είναι ετήσιος και αποτελεί σημαντική ασπίδα για την υγεία των εργαζομένων αλλά και τον νοσηλευόντων . Θα παρουσιαστεί έρευνα στο Γ.Ν.Α. Γεώργιος Γεννηματάς στο οποίο συμμετέχουν ιατροί και νοσηλευτές, οι οποίοι εργάζονται στο νοσοκομείο. Σκοπός της έρευνας είναι να παρουσιάσουμε τις πεποιθήσεις των εργαζόμενων υγείας σχετικά με την διαδικασία του αντιγριπικού εμβολιασμού. Οι συμμετέχοντες απαντήσαν σε ένα ανώνυμο ερωτηματολόγιο, το οποίο θα αναλύσουμε στην παρούσα εργασία. Στόχος της εργασίας είναι να καταλήξουμε σε ένα συμπέρασμα σχετικά με την αποδοχή ή μη του αντιγριπικού εμβολιασμού από τους εργαζομένους και να αποκαλύψουμε τις πεποιθήσεις που τους οδηγούν στην τελική τους απόφαση. Η επεξεργασία των δεδομένων από τα ερωτηματολόγια έγινε μέσω του Microsoft Excel. Τα αποτελέσματα της μελέτης έδειξαν πως οι εργαζόμενοι υγείας λόγω των πεποιθήσεων τους σχετικά με την ασφάλεια και την αποτελεσματικότητα των εμβολίων, αλλά και τις ελλείψεις κινήτρων για εμβολιασμό οδηγούνται σε χαμηλά ποσοστά εμβολιασμού. Η σωστότερη ενημέρωση σχετικά με τον αντιγριπικό εμβολιασμό καθώς και η καθιέρωση κινήτρων είναι ο τρόπος με τον οποίο μπορούν να αυξηθούν μελλοντικά τα ποσοστά εμβολιασμού στους εργαζόμενους υγείας.
Negative pressure wound therapy (NPWT) on closed incisions to prevent surgical site infection in high-risk patients in hepatopancreatobiliary surgery: study protocol for a randomized controlled trial—the NP-SSI trial
Creators: name: Brennfleck, Frank W.
name: Linsenmeier, Lena
name: Junger, Henrik H.G.
name: Schmidt, Katharina M.
name: Werner, Jens M.
name: Woehl, Daniel
name: Zeman, Florian
name: Mutzbauer, Ingrid
name: Hutchinson, James A.
name: Geissler, Edward K.
name: Schlitt, Hans J.
name: Brunner, Stefan M.
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: COMPLICATIONS; RESECTION; PREVALENCE; RECURRENCE; LAPAROTOMY; MANAGEMENT; DRESSINGS; OUTCOMES; IMPACT; NP-SSI; SSI; NPWT; ciNPWT; Incision management; Prevena; Wound infection; HPB surgery; Randomized controlled trial
subject: 610 Medizin

description: BackgroundIncisional surgical site infections (iSSI) in hepatopancreatobiliary (HPB) surgery usually lead to prolonged hospital stays, consume valuable resources, and impact on patients' outcome. Prophylactic closed incision negative pressure wound therapy (ciNPWT) to decrease wound complications has become available. Owing to an increasing number of studies, evidence for superiority in many indication areas has accumulated; however, in general surgery, there are a few data and those have shown contradictory results.MethodsIn this monocentric, prospective, randomized, controlled, two-armed study, the influence of ciNPWT on incisional surgical site infection rates after HPB operations will be investigated. A total of 222 patients will be randomized 1:1 to an interventional group (7-day treatment with ciNPWT) or a control group (treated with gauze dressing). The primary parameter to evaluate efficacy is the rate of incisional SSIs within 30days after surgery. Additionally, several clinically relevant secondary outcomes will be assessed.DiscussionA reduction in the rate of incisional SSIs would not only lead to a significant cost reduction and shorter postoperative length of stay, but may also improve postoperative quality of life for patients. While earlier publications have shown advantages for ciNPWT, recent studies did not confirm a positive effect regarding iSSI rate. Even if iSSI rate is not reduced, findings obtained from the secondary endpoints may be of clinical relevance, such as reduction of wound complication rates.Trial registrationThis trial has been registered in the German Clinical Trials Register, DRKS 00015136. Registered on 19 February 2019 and has been approved by the local ethics committee of the University of Regensburg: 18-1225-101.
Comparison of venous couplers versus hand-sewn technique in 4577 cases of DIEP-flap breast reconstructions – A multicenter study
Creators: name: Heidekrueger, Paul
name: von Fritschen, Uwe
name: Moellhoff, Nicholas
name: Germann, Gunter
name: Giunta, Riccardo
name: Zeman, Florian
name: Prantl, Lukas
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: MICROVASCULAR ANASTOMOTIC COUPLER; OUTCOMES; HEAD;
subject: 610 Medizin

description: Introduction Venous anastomosis remains to be a challenging step in microsurgical tissue transfer and venous complications constitute to a common reason for free flap failure. While several studies have compared mechanical vs. hand-sewn venous anastomoses, there is no large-series study comparing the type of anastomosis exclusively in DIEP flap breast reconstructions. Patients and Methods Between 2011 and 2019, 3926 female patients underwent 4577 free DIEP-flap breast reconstructions in 22 different breast cancer centers. Patient data was collected via an online database, files were screened and cases were divided into a hand- (HA) and a coupler-anastomosis (CA) group. Complications were accounted for and the two groups were then compared. Results Mean ischemia time was significantly shorter in the CA group (46.88 +/- 26.17 vs. 55.48 +/- 24.70 min; p < .001), whereas mean operative time was comparable (316 +/- 134.01 vs. 320.77 +/- 120.29 minutes; p = .294). We found no significant difference between both groups regarding the rate of partial (CA: 1.0% vs. HA: 1.3%) and total flap loss (CA: 2.2% vs. HA: 1.8%). However, revision rates were significantly higher in the CA group (CA: 10.5% vs. HA: 7.9%; p = .003), with higher numbers of arterial (2.3 vs. 0.9%; p < .001) and venous thromboses (3.4 vs. 1.8%; p = .001) accounting for this finding. Conclusions All taken into account, our findings do support the feasibility of venous coupler anastomoses in principle, however the inflationary use of coupler devices should be evaluated critically.
Tingis elongata
Creators: name: Heiss, Ernst
name: Eckelt, Andreas
name: Lederwasch, Manfred
name: Unterasinger, Romed
name: T, Familie
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Tingidae
Tingis
Tingis elongata

description: Tingis elongata (FIEBER, 1861)
D Z A A l g e r i e n: Bechar, Beni Abbes/ 70 km nördlich, 1 Ex., 17. IV. 1966, leg. Eckerlein H.
J O R J o r d a n i e n: Schambak, 1 Ex., 24. V. 1968, leg. Klapperich J.
description: Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 124, DOI: 10.5281/zenodo.7507194
Additional file 8: of Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection
Creators: name: Tamsyn Derrick
name: Last, Anna
name: Burr, Sarah
name: Roberts, Chrissy
name: Nabicassa, Meno
name: Cassama, Eunice
name: Bailey, Robin
name: Mabey, David
name: Burton, Matthew
name: Holland, Martin
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Focused list of published roles for miR that are differentially expressed in follicular trachoma that relate to inflammation or fibrosis. (PDF 59Â kb)
Quantized and Interpretable Learning Scheme for Deep Neural Networks in Classification Task
Creators: name: Maleki, Alireza
name: Lavaei, Mahsa
name: Bagheritabar, Mohsen
name: Beigzad, Salar
name: Abadi, Zahra
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: Deep learning techniques have proven highly effective in image classification, but their deployment in resourceconstrained environments remains challenging due to high computational demands. Furthermore, their interpretability is of high importance which demands even more available resources. In this work, we introduce an approach that combines saliency-guided training with quantization techniques to create an interpretable and resource-efficient model without compromising accuracy. We utilize Parameterized Clipping Activation (PACT) to perform quantization-aware training, specifically targeting activations and weights to optimize precision while minimizing resource usage. Concurrently, saliency-guided training is employed to enhance interpretability by iteratively masking features with low gradient values, leading to more focused and meaningful saliency maps. This training procedure helps in mitigating noisy gradients and yields models that provide clearer, more interpretable insights into their decision-making processes. To evaluate the impact of our approach, we conduct experiments using famous Convolutional Neural Networks (CNN) architecture on the MNIST and CIFAR-10 benchmark datasets as two popular datasets. We compare the saliency maps generated by standard and quantized models to assess the influence of quantization on both interpretability and classification accuracy. Our results demonstrate that the combined use of saliency-guided training and PACT-based quantization not only maintains classification performance but also produces models that are significantly more efficient and interpretable, making them suitable for deployment in resource-limited settings.
Comparative genetic analysis of invasive mosquito species in Belgium supports diverse introduction pathways.
Creators: name: Kratz, Fanny
name: Vanden Abeele, Samuel
name: Deblauwe, Isra
name: Hermy, Marie
name: Vanderheyden, Ann
name: Smitz, Nathalie
name: Schneider, Anna
name: Vanslembrouck, Adwine
name: Delbecque, Justine
name: Breugelmans, Karin
name: Segers, Brigitte
name: De Meyer, Marc
name: Backeljau, Thierry
name: Müller, Ruth
name: Rebolledo, Javiera
name: Van Bortel, Wim
Publisher: name: Zenodo
Year: 2024

description: Invasive mosquitoes present challenges to both public health and ecosystems, demanding a comprehension of their dispersal patterns and genetic makeup. This study integrates genetic analyses of two invasive mosquito species in Belgium, Aedes albopictus and Aedes japonicus, to clarify their introduction pathways and dispersal dynamics. Data were gathered through two mosquito monitoring programs, MEMO and MEMO+, with specimens collected at various points of entry (PoE), including international import companies, highway parking lots, and residential areas. A total of 254 Ae. albopictus and 292 Ae. japonicus specimens were analysed.

The northward expansion of Ae. albopictus into Belgium was investigated via active monitoring at PoEs and citizen science initiatives. Thirteen distinct COI haplotypes were identified, with one prevalent haplotype across sampling locations. The disparity in haplotype composition at import companies (indicative of long-distance introductions) versus parking lots/residential areas (suggestive of medium-distance introductions) in Belgium corroborates field observations, where tiger mosquitoes are presumed to hitchhike from established populations in neighbouring countries via passive ground transport.

The analysis of seven microsatellite loci within Ae. japonicus populations disclosed genetic disparities between specimens collected at one PoE before and after eradication attempts, hinting at potential new introductions after elimination campaigns. Furthermore, clustering analysis unveiled a genetic correlation between Belgian specimens collected at the border with Germany and populations in western Germany, underscoring the influence of human-mediated transport on invasion pathways.

These comparative genetic analyses underscore the significance of vigilant monitoring and targeted control strategies. The genetic investigation of Ae. albopictus and Ae. japonicus enhances our comprehension of their introduction pathways, which is important for effective management and mitigation of invasive species' impacts on public health and ecosystems.
In vivo comparison of braided (Accero) and laser-cut intracranial stents (Acclino, Credo): evaluation of vessel responses at subacute and mid-term follow-up in a rabbit model
Creators: name: Mühl-Benninghaus, Ruben
name: Tomori, Toshiki
name: Krajewski, Stefanie
name: Dietrich, Philipp
name: Simgen, Andreas
name: Yilmaz, Umut
name: Brochhausen, Christoph
name: Kießling, Mara
name: Reith, Wolfgang
name: Cattaneo, Giorgio
Publisher: name: Universität Regensburg
Year: 2020
Subjects: subject: In vivo comparison of braided and laser-cut stents; Thromboembolism; Neointima
subject: 610 Medizin

description: This study aimed to investigate in vivo two stent technologies, with particular emphasis on thrombogenicity and inflammatory vessel remodeling processes. The micro-stents tested in this study were developed for intracranial aneurysm treatment. In our study twelve, New Zealand white rabbits were divided into two groups: 18 laser-cut stents (LCS) and 18 braided stents (BS) were impanated without admiration of antiplatelet medication. Three stents were implanted into each animal in the common carotid artery, subclavian artery, and abdominal aorta. Digital subtraction angiography was performed before and after stent implantation and at follow-up for the visualization of occurring In-stent thromboembolism or stenosis. The Stents were explanted for histopathological examination at two different timepoints, after 3 and 28 days. Angiographically neither in-stent thrombosis nor stenosis for both groups was seen. There was a progressive increase in the vessel diameter, which was more pronounced for BS than for LCS. We detected a higher number of thrombi adherent to the foreign material on day 3 for BS. On day 3, the neointima was absent, whereas the complete formation observed was on day 28. There was no significant difference between both groups regarding the thickness of the neointima. The in vivo model of our study enabled the evaluation of blood and vessel reactions for two different stent technologies. Differences in vessel dimension and tissue around the stents were observed on day 28. Histological analysis on day 3 enabled the assessment of thrombotic reactions, representing an important complementary result in long-term studies. [GRAPHICS] .