cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Mechanisms for establishing transcriptional competence of tissue-specific genes in pluripotent stem cells
Creators: name: Liber, Daniel
Publisher: name: Imperial College London
Year: 2008

description: Tissue-specific genes have been found to be epigenetically marked in embryonic stem cells by different combination of histone modifications. These marks are believed to prime genes for activation at later stages of development. Previous work has revealed the presence of one such signature on one enhancer of the mouse λ5-VpreB1 locus, which is expressed at the pro- and pre-B cell stage of B lymphocyte development. This element, which has been called Early- Transcriptional Competence Mark (ETCM), is characterised by the presence of tightly localised peaks of histone H3K4 methylation and H3K9 acetylation. However, the ETCM lacks the trimethylation of H3K27 that defines bivalent domains at many tissue-specific genes in ES cells. The results described in this thesis show that that two ES cell transcription factors, Sox2 and Foxd3, bind to the λ5-VpreB1 ETCM in ES cells. Analysis of factor binding to the λ5-VpreB1 locus at the proB cell stage of B-cell development showed that the same sequences are occupied by the B-cell specific factors Sox4 and Foxp1. Chromatin immunoprecipitation and microarray analysis (ChIP-on-Chip) showed that Sox2 and Foxd3 are bound to a number of ETCM-like elements in ES cells, as well as bivalent domains, suggesting that they are involved in the establishment and maintenance of these epigenetic marks in ES cells. Knockdown of Sox2 by siRNA confirmed its involvement in the methylation of H3K4 on these DNA regions. Based on these data, I propose a factor-relay model in which embryonic stem cell transcription factors generate epigenetic signatures at key regulatory elements of tissue-specific genes. During differentiation these proteins are replaced by related factors, which share their DNA-binding profile, and play an important role in activating tissue-specific transcription.
Flows and Duality Symmetries in N=1 Supersymmetric Gauge Theories
Creators: name: Aharony, O.
name: Sonnenschein, J.
name: Yankielowicz, S.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We present more examples of dual N=1 SUSY gauge theories. This set of theories is connected by flows to both Seiberg's and Kutasov's dual theories. This provides a unifying picture of the various dual theories. We investigate the dual theories, their flat directions and mass perturbations.
description: 31 pages, uses harvmac.tex and tables.tex Minor changes - version accepted to Nucl. Phys. B
Letter from the U.S. Army Corps of Engineers, Fort Worth District to National Park Service, Supplemental HABS/HAER Documentation
Creators: name: W.H. Hill, P.E.
Publisher: name: U.S. Army Corps of Engineers, Fort Worth
Year: 1990
Subjects: Charles County (County)
Nanjemoy Creek
Potomac River
Maryland (State / Territory)
Port Tobacco River
Blossom Point, MD
Cedar Neck Point
18CH216
Ballast House
Domestic Structures
House
Domestic Structure or Architectural Complex
Collections Management
Heritage Management

description: A letter to the National Park Services from the U.S. Army Corps of Engineers, Fort Worth District submitting supplemental Historic American Buildings Survey/Historic American Engineering Record documentation for the Ballast House.
Cryptofavognathus anatolicus Do ğ an & Dönel 2010
Creators: name: LIU, DONG
name: YI, TIAN-CI
name: XU, YUN
name: ZHANG, ZHI-QIANG
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Acari
Cryptognathidae
Cryptofavognathus
Cryptofavognathus anatolicus

description: Cryptofavognathus anatolicus Do ğ an & Dönel, 2010: 37
— Holotype female (ZMAU), from moss on stone, Ağcaalan Village, Erbaa District, Tokat Province, Turkey (40°38'31''N, 36°40'50''E, 550 m).
description: Published as part of LIU, DONG, YI, TIAN-CI, XU, YUN & ZHANG, ZHI-QIANG, 2013, Hotspots of new species discovery: new mite species described during 2007 to 2012, pp. 1-102 in Zootaxa 3663 (1) on page 66, DOI: 10.11646/zootaxa.3663.1.1, http://zenodo.org/record/5630595
The Role of BRF1 and BRF2 in the Immune Response
Creators: name: Crawford, Rebecca
Publisher: name: Imperial College London
Year: 2008

description: Tristetraprolin (TTP), butyrate response factor 1 (BRF1) and butyrate response factor 2 (BRF2) are members of a family of zinc finger containing ARE binding proteins known as the Zfp36 family. They all possess a conserved tandem zinc finger domain, which facilitates their binding to mRNAs that contain adenosine/uridine rich elements (ARE) in their 3’ untranslated region (3’UTR). Binding to the target mRNA results in its destabilisation. Several mRNAs containing an ARE in their 3’UTR are stabilised by the mitogen activated protein kinase (MAPK) p38 pathway. Both the expression and the mRNA destabilising function of TTP are controlled by the p38 MAPK pathway. Much less is known about BRF1 and BRF2 functions, and it is not clear whether their expression or function is regulated by the p38 MAPK pathway. So far no difference has been seen in the binding specificities of the three proteins in vitro, however the phenotypes of knockout mice suggest that they have distinct functions, and may have different mRNA targets in vivo. Western blotting and quantitative PCR (qPCR) have been used to investigate the expression of members of the Zfp36 family. RNA interference was used to knock down the expression of BRF1 and BRF2 in HeLa cells, and the effects on p38-regulated inflammatory mediator expression were examined. BRF1-/- mouse embryonic fibroblast (MEF) cell lines were used to investigate the function of this family member. No evidence that BRF1 or BRF2 contributes to the post-transcriptional regulation of inflammatory mediators by the p38 MAPK pathway in HeLa cells or MEFs was found. BRF1 null MEFs over-expressed IL-6, protein, IL-6 mRNA and Cox-2 mRNA but did not over-express KC protein. The hypothesis that BRF1 is regulating IL-6 and Cox-2 by controlling mRNA stability was disproved. As a result investigation of the transcriptional regulation of these genes was researched. Primary transcript qPCR showed that both IL-6 and Cox-2 under-go more rapid transcription in BRF1-/- MEFs. This suggests that IL-6 and Cox-2 are indirect targets of BRF1 and that their regulation is through a transcription factor which is itself a target of BRF1.
Nucleation Process in Asymmetric Nuclear Matter
Creators: name: Menezes, D. P.
name: Providencia, C.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: An extended version of the non linear Walecka model, with rho mesons and eletromagnetic field is used to investigate the possibility of phase transitions in hot (warm) nuclear matter, giving rise to droplet formation. Surface properties of asymmetric nuclear matter as the droplet surface energy and its thickness are also examined.
description: 25 pages, 6 figures, LATEX, first page missing
Baby Skyrme models for a class of potentials
Creators: name: Eslami, P.
name: Zakrzewski, W. J.
name: Sarbishaei, M.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider a class of (2+1) dimensional baby Skyrme models with potentials that have more than one vacum. These potentials are generalisation of old and new baby Skyrme models;they involve more complicated dependence on phi_3.We find that when the potential is invariant under phi_3 -> -phi_3 the configuration corresponding to the baby skyrmions lying "on top of each other" are the minima of the energy. However when the potential breaks this symmetry the lowest field configurations correspond to separated baby skyrmions. We compute the energy distributions for skyrmions of degrees between one and eight and discuss their geometrical shapes and binding energies. We also compare the 2-skyrmion states for these potentials. Most of our work has been performed numerically with the model being formulated in terms of three real scalar fields (satisfying one constraint).
description: LaTeX, 14 pages, 10 figures
Letter from the U.S. Army Research Laboratory to SHPO, Special Agent Training at Blossom Point Field Test Facility
Creators: name: Roudebush, Ray
Publisher: name: U.S. Army Research Laboratory
Year: 1995
Subjects: Charles County (County)
Nanjemoy Creek
Potomac River
Maryland (State / Territory)
Port Tobacco River
Blossom Point, MD
Cedar Neck Point
18CH227
18CH155
Collections Management
Heritage Management

description: Responding letter from the Chief of Division of Public Works at the US Army Research Laboratory in Adelphi to the Director of Historical and Cultural Programs Department of Housing and Community Development in regards to possible special agent training at Blossom Point Field Test Facility. Enclosed is a copy of the Phase I Archaeological Survey of Twelve Areas at the Blossom Point Test Facility depicting and describing project locations in reference to the proposed and current training locations.
Effects of a high-phosphorus diet on the gut microbiota in CKD rats
Creators: name: Ye, Guoxin
name: Yang, Wei
name: Bi, Zhaori
name: Huang, Liya
name: Liu, Fang
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Physiology
subject: Ecology
subject: Biological Sciences not elsewhere classified

description: To investigate whether high-phosphorus diets alter gut microbiota in healthy rats and chronic kidney disease (CKD) rats. In this 4-week randomized controlled trial, healthy rats and CKD rats were fed a regular-phosphorus (Pi: 0.8%) and high-phosphorus (Pi: 1.2%) diet. The subjects were divided into four groups: sham-group rats with regular-phosphorus diet intervention (CTL group), sham-group rats with high-phosphorus diet intervention (CTLP group), CKD model rats with regular-phosphorus diet intervention (CKD group), and CKD model rats with high-phosphorus diet intervention (CKDP group). The V3-V4 region of the 16S rRNA gene was sequenced to study the effect of a high-phosphorus diet on gut microbiota. A high-phosphorus intervention increased systolic blood pressure (SBP) and parathyroid hormone (PTH) in CTL and CKD rats but did not change serum creatinine and 25(OH)D levels. After the high-phosphorus diet, serum phosphate and fibroblast growth factor 23 (FGF23) increased in the CKDP group compared with the CKD group. The gut microbiota was significantly altered after intervention with a high-phosphorus diet in CTL and CKD group rats. A high-phosphorus diet reduced the Shannon index values of gut microbiota in all rats. The Chao1 and Ace indexes were decreased in the CTL group after high-phosphorus diet intervention. Some microbial genera were elevated significantly after high-phosphorus dietary intervention, such as Blautia and Allobaculum. The main bacteria linked to SBP and FGF23 also correlated directly with creatinine. After high-phosphorus diet intervention, the bacteria Prevotella were positively related to SBP in CTLP and CKDP groups. High-phosphorus diets were associated with adverse changes in gut microbiota and elevated SBP, which may have adverse consequences for long-term health outcomes.
Three Point Functions on the Sphere of Calabi-Yau d-Folds
Creators: name: Sugiyama, Katsuyuki
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Using mirror symmetry in Calabi-Yau manifolds M, three point functions of A(M)-model operators on the genus $0$ Riemann surface in cases of one-parameter families of $d$-folds realized as Fermat type hypersurfaces embedded in weighted projective spaces and a two-parameter family of $d$-fold embedded in a weighted projective space ${\amb}$ are studied. These three point functions ${\corr{\,{{\cal O}^{(1)}_{a}}\, {{\cal O}^{(l-1)}_{b}}\, {{\cal O}^{(d-l)}_{c}}\, }}$ are expanded by indeterminates ${q_l}$=${e^{2πi {t_l}}}$ associated with a set of {\kae} coordinates $\{{t_l}\}$ and their expansion coefficients count the number of maps. From these analyses, we can read fusion structure of Calabi-Yau A(M)-model operators. In our cases they constitute a subring of a total quantum cohomology ring of the A(M)-model operators. In fact we switch off all perturbation operators on the topological theories except for marginal ones associated with {\kae} forms of M. For that reason, the charge conservation of operators turns out to be a classical one.
description: 22 pages, LaTex file
Cheylostigmaeus urhani Donel
Creators: name: LIU, DONG
name: YI, TIAN-CI
name: XU, YUN
name: ZHANG, ZHI-QIANG
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Stigmaeidae
Cheylostigmaeus
Cheylostigmaeus urhani

description: Cheylostigmaeus urhani Dönel & Do ğ an, 2011: 4
— Holotype male (ZMAU), from grassy soil, Köse Mountain, Turkey (40°16'23''N, 39°37'51''E, 1758 m).
description: Published as part of LIU, DONG, YI, TIAN-CI, XU, YUN & ZHANG, ZHI-QIANG, 2013, Hotspots of new species discovery: new mite species described during 2007 to 2012, pp. 1-102 in Zootaxa 3663 (1) on page 66, DOI: 10.11646/zootaxa.3663.1.1, http://zenodo.org/record/5630595
U.S. Army Research Laboratory Cultural Resources Management Plan, BPI_0505
Creators: name: Custer, Jay F.
Publisher: name: KFS Historic Preservation Group
Year: 1993
Subjects: Charles County (County)
Nanjemoy Creek
Potomac River
Maryland (State / Territory)
Port Tobacco River
Blossom Point, MD
Cedar Neck Point
Early Woodland
Middle Woodland
Late Woodland
PaleoIndian
Archaic
Early Archaic
Historic
Middle Archaic
Late Archaic
Euroamerican
18CH216
Ballast House
Ceramic
Chipped Stone
Collections Management
Heritage Management

description: The Cultural Resource Management Plan (CRMP) presented here provides guidelines and procedures which will enable the U.S. Army Research Laboratory (ARL) to meet its legal responsibilities for theidentification, evaluation, and treatment of cultural resource properties under its jurisdiction. This document is designed to be of use to multiple audiences who are concerned with the management or preservation of the cultural resources contained within the limits of the U.S. Army Research Laboratory (ARL). These audiences include the U.S. Army Materiel Command (AMC) and the U.S. Army Laboratory Command (LABCOM), ARL staff, State and Federal cultural resource managers, professional archaeologists, and the general public.
Nuclear liquid-gas phase transition within the lattice gas model
Creators: name: Borg, J.
name: Mishustin, I. N.
name: Bondorf, J. P.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the nuclear liquid-gas phase transition on the basis of a two-component lattice gas model. A Metropolis type of sampling method is used to generate microscopic states in the canonical ensemble. The effective equation of state and fragment mass distributions are evaluated in a wide range of temperatures and densities. A definition of the phase coexistence region appropriate for mesoscopic systems is proposed. The caloric curve resulting from different types of freeze-out conditions are presented.
description: 13 pages including 4 figures
Supplement from Plumage redness signals mitochondrial function in the house finch
Creators: name: Hill, Geoffrey E.
name: Hood, Wendy R.
name: Ge, Zhiyuan
name: Grinter, Rhys
name: Greening, Chris
name: Johnson, James D.
name: Park, Noel R.
name: Taylor, Halie A.
name: Andreasen, Victoria A.
name: Powers, Matthew J.
name: Justyn, Nicholas M.
name: Parry, Hailey A.
name: Kavazis, Andreas N.
name: Zhang, Yufeng
Publisher: name: The Royal Society
Year: 2019

description: Supplemental text with legend for video, details for structural model.
HABS/HAER Inventory for the Woodbridge Research Facility, BPI_0108
Creators: name: Buchanan, David G.
Publisher: name: U.S. Department of the Interior National Park Service
Year: 1982
Subjects: Charles County (County)
Nanjemoy Creek
Potomac River
Maryland (State / Territory)
Port Tobacco River
Blossom Point, MD
Cedar Neck Point
Woodbridge Research Facility
Building 203
Building 208
Building 201
Collections Management
Architectural Documentation
Heritage Management

description: HABS/HAER (Historic American Buildings Survey/Historic American Engineering Record) Inventory for the Woodbridge Research Facility. The Woodbridge Research Facility is a subinstallation of Harry Diamond Laboratories in Adelphi, Maryland. In 1952, the Army built a major radio transmitting facility on this site, which was then an isolated woodland. Composed of three principal communications buildings and a transmission tower, the facilities had a counterpart receiving station in La Plata, Maryland. The facility was deactivated in July 1969 and in July 1970, 641 acres at the Woodbridge site were transferred to the U.S. Army Materiel Command. The isolation of the facility and the high moisture content of the soil led to its use as an electromagnetic pulse development and test site. At the same time, the remaining seven acres at Woodbridge (the housing site near the main entrance) were transferred to the U.S. Army Engineer Center at Ft. Belvoir, Virginia. In July 1971, HDL acquired the facility when the Army consolidated its nuclear weapons effects research and test activities. The facility currently is used for testing the vulnerability of both new and fielded tactical systems to the effects of nuclear attack. Since actual nuclear detonations testing is now prohibited, a realistic tactical environment is simulated by means of high-voltage electromagnetic pulse (EMP) testing equipment. The 21 permanent buildings at the research facility (19 of which were constructed prior to acquisition by HDL) support this testing activity. All of the research facility's buildings were erected between 1952 and 1972 and are of simple utilitarian construction.
Study of $CP$ Violations in $B^-\rightarrow K^- π^+π^-$ and $B^-\rightarrow K^- f_0(500)$ decays in the QCD factorization approach
Creators: name: Qi, Jing-Juan
name: Wang, Zhen-Yang
name: Zhang, Zhen-Hua
name: Xu, Jing
name: Guo, Xin-Heng
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Within the QCD factorization approach, we study the $CP$ violations in $B^-\rightarrow K^-π^+π^-$ and $B^-\rightarrow K^- f_0(500)$ decays. We find the experimental data of the localized $CP$ asymmetry in $B^-\rightarrow K^-π^+π^-$ decays in the region $m_{K^-π^+}^2<15$ $\mathrm{GeV}^2$ and $0.08
description: 13 pages, 4 figures
The use of rapid sampling microdialysis in monitoring human bowel and anastomosis ischaemia
Creators: name: Deeba, Samer
Publisher: name: Imperial College London
Year: 2009

description: Intestinal ischaemia especially in the postoperative period is a complication that is dreaded by all general surgeons and poses a considerable rise in mortality and morbidity of patients, not to mention the burden it puts on the physician and on the healthcare system. Its diagnosis is always subjective relying mostly on the physicians’ awareness and clinical suspicion rather than on any quantitative method. This project explores a quantitative tool and adapts online rapid sampling microdialysis (from its use in monitoring brain tissue ischaemia) to monitor ischaemia in human bowel and bowel anastomosis. It describes its translation from the bench top model, to the pilot model, to the animal model, and finally its application in the clinical setting to monitor patients for bowel ischaemia. The online microdialysis analyzer used in monitoring brain tissue in Kings College Hospital was modified and converted for use in the setting to monitor bowel in the labs of the Bioengineering Department at Imperial College London, under collaboration with the Department of Bio Surgery and Surgical Technology. The system was designed and construction supervised by Dr. Martyn Boutelle; and work on the system to construct and optimize carried out by PhD student Emma Corcoles. The clinical collaborate of the project was supervised by Professor Ara Darzi and carried out by Mr. Samer Deeba with joint supervision by Professor George Hanna. The catheter, connections, and deployment was optimized at St. Mary’s Hospital, part of Imperial College NHS trust. This project did prove the efficacy of microdialysis in monitoring bowel ischaemia in the clinical setting, but needs further work and development in the design of the catheter and miniaturizing the analyzer to be more reliable and robust. Multicenter trials are needed to gain its wide acceptance in the clinical practice.
The Reeh-Schlieder property for ground states
Creators: name: Jaekel, Christian
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Recently it has been shown that the Reeh-Schlieder property w.r.t. thermal equilibrium states is a direct consequence of locality, additivity and the relativistic KMS condition. Here we extend this result to ground states.
description: plain tex, 11 pages, An unnecessary strong assumption has been replaced by a more adequate one in Definition 2.1
Eustigmaeus varius Donel
Creators: name: LIU, DONG
name: YI, TIAN-CI
name: XU, YUN
name: ZHANG, ZHI-QIANG
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Stigmaeidae
Eustigmaeus
Eustigmaeus varius

description: Eustigmaeus varius Dönel & Do ğ an, 2011: 16
— Holotype female (ZMAU), from decayed bark of Pinus sp., Reşadiye, Turkey (40°18'27''N, 37°35'01''E, 996 m).
description: Published as part of LIU, DONG, YI, TIAN-CI, XU, YUN & ZHANG, ZHI-QIANG, 2013, Hotspots of new species discovery: new mite species described during 2007 to 2012, pp. 1-102 in Zootaxa 3663 (1) on page 66, DOI: 10.11646/zootaxa.3663.1.1, http://zenodo.org/record/5630595
R code social information use from Identification of acutely sick people: individual differences and social information use
Creators: name: Kurvers, Ralf H. J. M.
name: Wolf, Max
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The R code of the social informatino use rules
Map, Cedar Point Neck Farms Circa 1908, BPI_0272
Creators: name: System User
Year: 1985
Subjects: Charles County (County)
Nanjemoy Creek
Potomac River
Maryland (State / Territory)
Port Tobacco River
Blossom Point, MD
Cedar Neck Point
18CH216
Ballast House
Collections Management
Heritage Management

description: Figure 2.2. Cedar Point Neck farms circa 1908.
Beurling-Fourier algebras of compact quantum groups: characters and finite dimensional representations
Creators: name: Franz, Uwe
name: Lee, Hun Hee
Publisher: name: arXiv
Year: 2018
Subjects: subject: Operator Algebras (math.OA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 43A30, 20G42

description: In this paper we study weighted versions of Fourier algebras of compact quantum groups. We focus on the spectral aspects of these Banach algebras in two different ways. We first investigate their Gelfand spectrum, which shows a connection to the maximal classical closed subgroup and its complexification. Secondly, we study specific finite dimensional representations coming from the complexification of the underlying quantum group. We demonstrate that the weighted Fourier algebras can detect the complexification structure in the special case of $SU_q(2)$, whose complexification is the quantum Lorentz group $SL_q(2,\mathbb{C})$.
description: Another substantial updates. 29 pages
title: KLIMONAS-Ch24-A12 - Description taphonomique des principaux assemblages fauniques de Klimonas, comparaisons et regroupements
title: KLIMONAS-Ch24-A12 - Taphonomic description of the main faunal assemblages from Klimonas, comparisons and grouping
Creators: name: VIGNE, Jean-Denis
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: Annexe de : Vigne J.-D., Briois F., Guilaine J. (dir.), « Klimonas, un village néolithique pré-céramique ancien à Chypre », Gallia Préhistoire & Paléorient, Supplément international 1, CNRS Éditions, Paris, 2023.
description: Appendix of: Vigne J.-D., Briois F., Guilaine J. (eds.), « Klimonas, an Early Pre-Pottery Neolithic village in Cyprus », Gallia Préhistoire & Paléorient, International Supplement 1, CNRS Éditions, Paris, 2023.
Short intro to Task 9.3: Making TipESM Science Actionable
Creators: name: Cvijanovic, Ivana
name: Chica, Laura
Publisher: name: Zenodo
Year: 2024

description: This presentation was part of the TipESM Kick-off Meeting which was held from 23 – 24 January 2024 in Copenhagen hosted by the Danish Meteorological Institute as well as online.

Date: 23 January 2024

Presenter: Ivana Cvijanovic and Laura Chica (ISGlobal)

Find the agenda overview of the TipESM Kick-off Meeting here.
Additional file 5 of Efficiency of dual-energy computed tomography enterography in the diagnosis of Crohn’s disease
Creators: name: Chen, Jinghao
name: Zhou, Jie
name: Yang, Jushun
name: Cong, Ruochen
name: Sun, Jinjie
name: Xiao, Jing
name: Shi, Jianhua
name: He, Bosheng
Publisher: name: figshare
Year: 2021
Subjects: Biophysics
Space Science
Physical Sciences not elsewhere classified
Medicine
Cell Biology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Additional file 5: Table S1. Subjective quantitative scores of images of blood vessels. Table S2. Subjective evaluation of imaging quality and noise as 5-point score. Table S3. Quantitative parameters of DECTE images for evaluating the activity of CD. Table S4. Clinical baselines of 72 patients with negative CTE. Table S5. Consistency of the subjective evaluation parameters between the two observers. Table S6. Comparisons of efficacy in CD diagnosis between NIC and fat value of intestinal wall during the small intestine phase of CTE. Table S7. Comparisons of efficacy in active CD between NIC and fat value of intestinal wall during the small intestine phase of CTE. Table S8. Comparison of diagnostic value between routine CTE+ VMI60keV and routine CTE at 120 kVp in CD diagnosis.
Time-scales for the development of thermodynamic equilibrium in hydrocarbon reservoirs
Creators: name: Besong, Donald Ojong
Publisher: name: Imperial College London
Year: 2009

description: This project investigates the time-scales for hydrocarbon components in an isothermal oil reservoir column to reach thermodynamic equilibrium under the competing influences of molecular diffusion and gravitational segregation by gravity diffusion. The influence of non ideal behaviour on the equilibrium compositional profile, as well as on the equilibrium time for some examples of binary and ternary hydrocarbon mixtures is also investigated. When the variation of hydrocarbon composition within a field cannot be described by standard steady-state models of gravity-diffusion equilibrium, it is usually assumed to be caused by some degree of hindrance to the connectivity of the oil volume, a situation known as reservoir compartmentalization. However, order of magnitude estimates of the time taken for thermodynamic equilibrium to be established by diffusion are similar to the ages of many hydrocarbon reservoirs (between 1 million and 100 million years). Thus it is possible that compositional variations within a reservoir may be simply due to there having been insufficient time from reservoir filling for diffusion to equilibrate compositions. It is important to determine the time-scales for vertical compositional gradients to be established in order to assess whether compositional profiles that are not in thermodynamic equilibrium are indicative of barriers to flow within the reservoir or simply that the reservoir fluids have not yet had time to establish a steady-state distribution. A macroscopic, numerical model of the thermodynamic behaviour of the reservoir fluids has been used for this investigation. The model has been validated against simple transient analytic solutions for molecular diffusion, as well as steady-state solutions for molecular/gravity diffusion in binary mixtures. It was found that a uniform mixture of methane and undecane will segregate over a vertical distance of 300m in a few hundred thousand years and that this timescale can be affected by non-ideal mixing and the relative proportions of the two components. Equilibrium time was found to be a function of the competing influences of molecular diffusion and gravitational segregation. We also use our model to investigate laboratory observations of compositional grading in ternary mixtures of methane, n-pentane and 1-methylnapthalene reported by Ratulowski et al. (2003) and why their numerical simulation produced an unexpectedly smaller separation when methylnaphthalene was replaced by n-undecane, although methylnaphthalene and undecane have almost the same molar weight. Our study also provides insight into the relative importance of density, molecular diffusion, initial composition and realmixture modelling (as opposed to ideal mixture assumptions) on compositional grading in a fluid more representative of a real crude oil.
The role of formyl peptide receptors within the hypothalamic pituitary adrenal axis
Creators: name: Buss, Nicholas Alexander Piers Sascha
Publisher: name: Imperial College London
Year: 2010

description: Annexin 1 (ANXA1) is an important mediator of the regulatory effects of glucocorticoids (GCs) within the neuroendocrine and host defence systems. Recent data suggest that it acts via a formyl peptide receptor (FPR) as a mediator of the negative feedback effects of GCs on adrenocorticotrophic hormone (ACTH) release. In the present study, in vitro and in vivo methods were used to detect and explore further the function of these receptors within the hypothalamo-pituitary-adrenocortical (HPA) axis. Lipopolysaccharide (LPS), given intra-peritoneally (i.p.) or centrally (i.c.v.), increased expression of mRNAs for ANXA1 and Fpr1, Fpr2 and Fpr3 in the spleen, pituitary and adrenal gland, but not in the brain. Given i.p., it also caused inflammatory cell infiltration in the adrenal gland, but not the pituitary, together with decreased vacuolation in the steroidogenic cells, increases in serum pro-inflammatory cytokines and corticosterone (CORT) and a subsequent loss of sensitivity to ACTH. The increases in ANXA1, Fpr1 and Fpr3 expression were dependent on inflammatory cell infiltration (predominantly eosinophils) but those of Fpr2 were not. The decrease in vacuolation was also independent of the inflammatory cell infiltration but was severely compromised by deletion of the genes encoding ANXA1 and Fpr2. Pharmacological studies on isolated adrenal cells in vitro suggest that ANXA1 may act via Fpr2 to inhibit ACTH-stimulated CORT release but that Fpr1 effects a tonic stimulatory effect on ACTH-driven steroidogenesis. These data suggest that ANXA1 and the FPRs play an important role within the adrenal in mediating the HPA responses to endotoxin and provide new evidence to suggest that infiltrating leukocytes are are also important in this regard.
R code correlations from Identification of acutely sick people: individual differences and social information use
Creators: name: Kurvers, Ralf H. J. M.
name: Wolf, Max
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The R code of the correlation analysis
Suburban Fixed Wireless Access Channel Measurements and Models at 28 GHz for 90% Outdoor Coverage
Creators: name: Du, Jinfeng
name: Chizhik, Dmitry
name: Feick, Rodolfo
name: Rodriguez, Mauricio
name: Castro, Guillermo
name: Valenzuela, Reinaldo. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Information Theory (cs.IT)
subject: Signal Processing (eess.SP)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Achieving adequate coverage with high gain antennas is key to realizing the full promise of the wide bandwidth available at cm/mm bands. We report extensive outdoor measurements at 28 GHz in suburban residential areas in New Jersey and Chile, with over 2000 links measured for same-street link types (vegetation blocked LOS) from 13 streets and other-street link types (true NLOS) from 7 streets, using a specialized narrowband channel sounder at ranges reaching 200 m. The measurements, applicable to fixed wireless access, involved a 55$^\circ$ transmit antenna placed on the exterior of a street-facing window and a 10$^\circ$ receive horn antenna spinning on top of a van mast at 3 m height, emulating a lamppost-mounted base station. Measured path gain-distance dependence is well represented by power-law models, and azimuth gains at the base are degraded through scattering by more than 4.3 dB for 10% of links. It was found that, with 51 dBm EIRP at the base station and 11 dBi antenna at an outdoor mounted terminal, 1 Gbps downlink rate can be delivered up to 100 m from a base station deployed in the same street with 90% coverage guarantee.
description: This work was presented in part at 2018 IEEE Symposium on Antennas and Propagation, Boston, MA, Jul. 2018
Computational studies of earth abundant and organo- catalytic systems
Creators: name: Goodfellow, Alister Stewart
Publisher: name: The University of St Andrews
Year: 2024
Subjects: Computational chemistry
Density Functional Theory
Homogeneous catalysis
Organocataysis
Enantioselectivity
Conformational sampling
Benchmarking
Machine learning

description: This thesis focuses on the application of Density Functional Theory (DFT) to manganese catalysed hydrogenation reactions (Part I) and organocatalytic reactivity (Part II). Part I: A DFT benchmarking study was performed to reproduce experimentally determined values of hydricity, the heterolytic metal hydride bond strength of 3d transition metal (TM) complexes (Chapter 4) to ensure an accurate methodology for work on these systems. This methodology was employed for the modelling of manganese catalysed enantioselective ketone hydrogenation (Chapter 5). Rational design led to a catalyst with improved stereocontrol by introducing steric bulk in the active site (Chapter 5). Further modification of the ligand backbone led to the identification of routes to improve selectivity and activity by varying sterics and electronics on the ligand (Chapter 5). Using the dataset generated, Machine Learning was performed to predict DFT level barrier heights from GFN2-xTB level descriptors, though the predictive power was limited by the distribution and size of the dataset (Chapter 6). Part II: DFT has been applied to a number of asymmetric reactions involving both isothiourea catalysis (Sections 9.1–9.5) and hydrogen bonding catalysis (Section 9.6). Isothiourea catalysts involve a chalcogen bonding interaction that locks the conformation of a key acyl ammonium intermediate, promoting facially-selective reactivity. The strength of the interaction can be modulated through decoration of the catalyst backbone (Section 9.1), though the nucleophilicity is key to retain catalytic activity over background reactions. DFT can be used to identify the stereodetermining transition states in reactivity (Sections 9.2–9.5) though some tailoring of methodology is required with large dipole moments (Section 9.2) and to adjust entropic contributions (Sec tion 9.3). GFN2-xTB performs well as a preoptimisation technique and for some transition states, but leads to overbinding of the chalcogen interaction, shortening the distance into the repulsive regime of DFT. This remains a powerful technique for conformational sampling, identifying representative low-lying conformations to accurately model diastereoselective rearrangement reactions (Section 9.6).
Dynamics of dissipative binary collisions
Creators: name: Fabbri, G.
name: Colonna, M.
name: Di Toro, M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: In this paper we discuss the reaction mechanisms that occur in the overlap zone for semi-peripheral heavy ion collisions at intermediate energies. In particular we focus on the development of neck instabilities, that could determine a possible increase of dynamical fluctuations. As observed in recent experimental data, at beam energies just above 10 MeV/A the most relevant expected consequence is the possibility to obtain large variances in the projectile-like and target-like observables. With increasing beam energy we pass to a mid-rapidity fragment production. In this way we predict a smooth transition from a deep-inelastic to a fragmentation reaction mechanism.
description: 14 pages, REVTEX, 2 ps figures, submitted to Phys.Rev.C
Centralized and distributed semi-parametric compression of piecewise smooth functions
Creators: name: Chaisinthop, Varit
Publisher: name: Imperial College London
Year: 2010

description: This thesis introduces novel wavelet-based semi-parametric centralized and distributed compression methods for a class of piecewise smooth functions. Our proposed compression schemes are based on a non-conventional transform coding structure with simple independent encoders and a complex joint decoder. Current centralized state-of-the-art compression schemes are based on the conventional structure where an encoder is relatively complex and nonlinear. In addition, the setting usually allows the encoder to observe the entire source. Recently, there has been an increasing need for compression schemes where the encoder is lower in complexity and, instead, the decoder has to handle more computationally intensive tasks. Furthermore, the setup may involve multiple encoders, where each one can only partially observe the source. Such scenario is often referred to as distributed source coding. In the first part, we focus on the dual situation of the centralized compression where the encoder is linear and the decoder is nonlinear. Our analysis is centered around a class of 1-D piecewise smooth functions. We show that, by incorporating parametric estimation into the decoding procedure, it is possible to achieve the same distortion- rate performance as that of a conventional wavelet-based compression scheme. We also present a new constructive approach to parametric estimation based on the sampling results of signals with finite rate of innovation. The second part of the thesis focuses on the distributed compression scenario, where each independent encoder partially observes the 1-D piecewise smooth function. We propose a new wavelet-based distributed compression scheme that uses parametric estimation to perform joint decoding. Our distortion-rate analysis shows that it is possible for the proposed scheme to achieve that same compression performance as that of a joint encoding scheme. Lastly, we apply the proposed theoretical framework in the context of distributed image and video compression. We start by considering a simplified model of the video signal and show that we can achieve distortion-rate performance close to that of a joint encoding scheme. We then present practical compression schemes for real world signals. Our simulations confirm the improvement in performance over classical schemes, both in terms of the PSNR and the visual quality.
R code obs and exp d prime and response bias from Identification of acutely sick people: individual differences and social information use
Creators: name: Kurvers, Ralf H. J. M.
name: Wolf, Max
Publisher: name: The Royal Society
Year: 2018
Subjects: subject: 170299 Cognitive Science not elsewhere classified
subject: FOS: Psychology
subject: 60801 Animal Behaviour
subject: FOS: Biological sciences

description: The R code of the simulations for determining observed and expected d prime and response bias
Some Reflections on Moduli, Their Stabilization and Cosmology
Creators: name: Dine, Michael
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We review some aspects of moduli in string theory. We argue that one should focus on {\it approximate moduli spaces}, and that there is evidence that such spaces exist non-perturbatively. We ask what it would mean for string theory to predict low energy supersymmetry. Aspects of two proposed mechanisms for fixing the moduli are discussed, and solutions to certain cosmological problems associated with moduli are proposed.
description: 22 pp. latex. Invited talk presented at ITP Conference on New Dimensions in Field Theory and String Theory, ITP Nov, 1999. Some typos and refs. fixed
Proceedings of the 1st International Workshop on Methods and Tools for Rigorous System Design
Creators: name: Bliudze, Simon
name: Bensalem, Saddek
Publisher: name: arXiv
Year: 2018
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: This volume contains the proceedings of the 1st International Workshop on Methods and Tools for Rigorous System Design (MeTRiD 2018), held on the 15th of April, 2018 in Thessaloniki, Greece as part of ETAPS 2018, the European Joint Conferences on Theory and Practice of Software. The term "Rigorous System Design" (RSD) denotes the design approach that is based on a formal, accountable and iterative process for deriving trustworthy and optimised implementations from models of application software, its execution platform and its external environment. Ideally, a system implementation is derived from a set of appropriate high-level models by applying a sequence of semantics-preserving transformations. The ambition of MeTRiD is to promote the use of formal methods, in general, and the RSD approach, in particular, in the industrial applications and, reciprocally, bring the attention of the formal methods researchers to such industrial applications in order to develop realistic case-studies and guide the evolution of tools. Striving towards this ambitious goal, we have solicited contributions of three types: - regular papers, presenting original research - case study papers, reporting the evaluation of existing modelling, analysis, transformation and code generation formalisms and tools on realistic examples of significant size - tool papers, describing new tool prototypes supporting the RSD flow and enhancements of existing ones We have received 13 submissions (7 regular, 4 tool and 2 case study papers), whereof 8 have been accepted for presentation at the workshop: - 5 regular papers - 2 tool papers - 1 case study paper In this volume, these papers are complemented by an invited paper by Joseph Sifakis.
The canonical connection in quantum mechanics
Creators: name: Levay, Peter
name: McMullan, David
name: Tsutsui, Izumi
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we investigate the form of induced gauge fields that arises in two types of quantum systems. In the first we consider quantum mechanics on coset spaces G/H, and argue that G-invariance is central to the emergence of the H-connection as induced gauge fields in the different quantum sectors. We then demonstrate why the same connection, now giving rise to the non-abelian generalization of Berry's phase, can also be found in systems which have slow variables taking values in such a coset space.
description: 19 pages, plain TeX
Supernova electron capture rates for 55Co and 56Ni
Creators: name: Langanke, K.
name: Martinez-Pinedo, G.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Nuclear Theory (nucl-th)
subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have calculated the Gamow-Teller strength distributions for the ground states and first excited states in 55Co and 56Ni. These calculations have been performed by shell model diagonalization in the pf shell using the KB3 interaction. The Gamow-Teller distributions are used to calculate the electron capture rates for typical presupernova conditions. Our 55Co rate is noticeably smaller than the presently adopted rate as it is dominated by weak low-lying transitions rather than the strong Gamow-Teller (GT) resonance which is located at a higher excitation energy in the daughter than usually parametrized. Although our 56Ni rate agrees with the presently adopted rate, we do not confirm the conventional parametrization of the GT centroid. Our results support general trends suggested on the basis of shell model Monte Carlo calculations.
description: 4 pages, 4 figures, RevTeX 3.1, to appear in Phys. Lett. B
Ledermuelleriopsis indiscretus Donel
Creators: name: LIU, DONG
name: YI, TIAN-CI
name: XU, YUN
name: ZHANG, ZHI-QIANG
Publisher: name: Zenodo
Year: 2013
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Stigmaeidae
Ledermuelleriopsis
Ledermuelleriopsis indiscretus

description: Ledermuelleriopsis indiscretus Dönel & Do ğ an, 2011: 31
— Holotype female (ZMAU), from moss on soil, between Koyulhisar-Reşadiye, Turkey (40°22'88''N, 37°21'46''E, 519 m).
description: Published as part of LIU, DONG, YI, TIAN-CI, XU, YUN & ZHANG, ZHI-QIANG, 2013, Hotspots of new species discovery: new mite species described during 2007 to 2012, pp. 1-102 in Zootaxa 3663 (1) on page 66, DOI: 10.11646/zootaxa.3663.1.1, http://zenodo.org/record/5630595
Hopf instantons and the Liouville equation in target space
Creators: name: Adam, C.
name: Muratori, B.
name: Nash, C.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We generalise recent results on Hopf instantons in a Chern--Simons and Fermion theory in a fixed background magnetic field. We find that these instanton solutions have to obey the Liouville equation in target space. As a consequence, these solutions are given by a class of Hopf maps that consist of the composition of the standard Hopf map with an arbitrary rational map.
description: Latex file, 11 pages, no figures
Supplementary Material for: Forecasting Future Trends in Obesity across Europe: The Value of Improving Surveillance
Creators: name: Pineda, E.
name: Sanchez-Romero, L.M.
name: Brown, M.
name: Jaccard, A.
name: Jewell, J.
name: Galea, G.
name: Webber, L.
name: Breda, J.
Publisher: name: Karger Publishers
Year: 2018
Subjects: Medicine

description: Objective: To project the prevalence of obesity across the WHO European region and examine whether the WHO target of halting obesity at 2010 levels by 2025 is achievable. Methods: BMI data were collected from online databases and the literature. Past and present BMI trends were extrapolated to 2025 using a non-linear categorical regression model fitted to nationally representative survey data. Where only 1 year of data was available, a flat trend was assumed. Where no data were available, proxy country data was used adjusted for demographics. Results: By 2025, obesity is projected to increase in 44 countries. If present trends continue, 33 of the 53 countries are projected to have an obesity prevalence of 20% or more. The highest prevalence is projected for Ireland (43%, 95% confidence interval (CI): 28-58%). Lithuania, Finland, and the Netherlands were each estimated to have an absolute increase of 2 percentage points in the prevalence of obesity between 2015 and 2025. Discussion: The quality of BMI data across Europe is highly variable, with fewer than 50% of the 53 countries having measured nationally representative data and often not enough data to interpret projections meaningfully. Nevertheless, the prevalence of obesity in the European Region appears to be increasing in most countries and, with it, the health and economic burden of its associated diseases. This paints a concerning picture of the future burden of obesity-related noncommunicable diseases across the region. Greater and continued effort for the implementation of effective preventive policies and interventions is required from governments.