cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Inverse regulation of biofilm formation and swarming motility in Pseudomonas aeruginosa by the transcriptional regulator GbuR
Creators: name: Ho, Ryan Calvin
Publisher: name: University of British Columbia
Year: 2015

description: Pseudomonas aeruginosa inversely regulates biofilm formation and swarming motility, which provides the advantage of allowing it to adapt to environmental conditions. These two surface-associated behaviors represent distinct infection states, with swarming being associated with an acute lifestyle, and biofilm formation exemplifying a chronic lifestyle. Thus the inverse regulation of biofilm formation and swarming motility has important implications for the mode of infection, which in turn influences the interaction between P. aeruginosa and an affected host. Recent studies have also shown that the inverse regulation of biofilm formation and swarming motility is under the control of a number of regulatory genes. Characterization of these genes will therefore provide insights into this regulatory phenomenon and its effect on virulence in P. aeruginosa. The aim of this study was to investigate the inverse regulation of biofilm formation and swarming motility by the transcriptional regulator GbuR. It was shown that mutation in gbuR resulted in a severe swarming defect, while biofilm formation was enhanced. Transcriptome analysis defined the modest regulon of gbuR, revealing a number of genes potentially involved in inversely regulating biofilm formation and swarming motility.
AC-driven Vortices and the Hall Effect in a Superconductor with a Tilted Washboard Pinning Potential
Creators: name: Shklovskij, Valerij A.
name: Dobrovolskiy, Oleksandr V.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The Langevin equation for a two-dimensional (2D) nonlinear guided vortex motion in a tilted cosine pinning potential in the presence of an ac is exactly solved in terms of a matrix continued fraction at arbitrary value of the Hall effect. The influence of an ac of arbitrary amplitude and frequency on the dc and ac magnetoresistivity tensors is analyzed. The ac density and frequency dependence of the overall shape and the number and position of the Shapiro-like steps on the anisotropic current-voltage characteristics are considered. The influence of a subcritical or overcritical dc on the time-dependent stationary ac longitudinal and transverse resistive vortex responses (on the frequency of an ac drive W) in terms of the nonlinear impedance tensor Z and the nonlinear ac response at W-harmonics are studied. Analytical formulas for 2D temperature-dependent linear impedance tensor Zl in the presence of a dc which depend on the angle a between the current-density vector and the guiding direction of the washboard planar pinning potential are derived and analyzed. Influence of a-anisotropy and the Hall effect on the nonlinear power absorption by vortices is discussed.
description: 17 pages, 8 figures
Model analysis and further results from When does reputation lie? Dynamic feedbacks between costly signals, social capital and social prominence
Creators: name: Dumas, Marion
name: Barker, Jessica L.
name: Power, Eleanor A.
Publisher: name: The Royal Society
Year: 2021
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour

description: The supplementary material presents proofs for the analytical model, detailed description of the agent-based model and further analysis.
Fault isolation and alarm design in non-linear stochastic systems
Creators: name: Alrowaie, Feras A.
Publisher: name: University of British Columbia
Year: 2015

description: In this project, first we propose a novel model-based algorithm for fault detection and isolation (FDI) in stochastic non-linear systems. The algorithm is established based on parameter estimation by monitoring any changes in the behaviour of the process and identifying the faulty model using a bank of particle filters running in parallel with the process model. The particle filters are used to generate a sequence of hidden states, which are then used in a log-likelihood ratio to detect and isolate the faults. The newly developed scheme is demonstrated through implementation in two highly non-linear case studies. Finally, the effectiveness and robustness of the proposed diagnostic algorithm are illustrated by comparing the results obtained by applying the algorithm to the multi-unit chemical reactor system using other FDI techniques, based on EKF and UKF state estimators. Second, we propose an approach based on particle filter algorithm to isolate actuator and sensor faults in stochastic non-linear and non-Gaussian systems. The proposed FDI approach is based on a state estimation approach using a general observer scheme (GOS), whereby a bank of particle filters is used to generate a set of residuals, each sensitive to all but one fault. The faults are then isolated by monitoring the behaviour of the residuals where the residuals of the faulty sensors or actuators behave differently than the faultless residuals. The approach is demonstrated through implementing two highly non-linear case studies. Non-linear stochastic systems pose two important challenges for designing alarms : (1) measurements are not necessarily Gaussian distributed and (2) measurements are correlated - in particular, for closed-loop systems. We therefore present an algorithm for designing alarms based on delay timers and deadband techniques for such systems, with unknown and known models. In the case of unknown models, our approach is based on Monte Carlo simulations. In the case of known models, it makes use of a probability density function approximation algorithm called particle filtering. The alarm design algorithm is illustrated through two simulation examples. We show that the proposed alarm design is effective in detecting the fault, even though the measurements are non-Gaussian.
Flat Pseudo-Riemannian Homogeneous Spaces with Non-Abelian Holonomy Group
Creators: name: Baues, Oliver
name: Globke, Wolfgang
Publisher: name: arXiv
Year: 2010
Subjects: subject: Differential Geometry (math.DG)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 53C30, 57S30, 20G05

description: We construct homogeneous flat pseudo-Riemannian manifolds with non-abelian fundamental group. In the compact case, all homogeneous flat pseudo-Riemannian manifolds are complete and have abelian linear holonomy group. To the contrary, we show that there do exist non-compact and non-complete examples, where the linear holonomy is non-abelian, starting in dimensions $\geq 8$, which is the lowest possible dimension. We also construct a complete flat pseudo-Riemannian homogeneous manifold of dimension 14 with non-abelian linear holonomy. Furthermore, we derive a criterion for the properness of the action of an affine transformation group with transitive centralizer.
Formation of Zn and Pb sulfides in a redox-sensitive modern system due to high atmospheric fallout
Creators: name: Smieja-Król, Beata
name: Pawlyta, Mirosława
name: Kądziołka-Gaweł, Mariola
name: Fiałkiewicz-Kozieł, Barbara
Publisher: name: arXiv
Year: 2022
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The study shows that the air-derived metal enrichment (up to 2.3 g Zn kg-1, 1.1 g Pb kg-1, and 62 mg Cd kg-1) is retained in a thin layer (~30 cm) around 10-15 cm below the peat surface. A combination of focused ion beam (FIB) technology and scanning (SEM) and transmission (TEM) electron microscopy reveals that micrometric spheroids are most characteristic for ZnS and (Zn,Cd)S, although the sulfides readily form pseudomorphs after different plant tissues resulting in much larger aggregates. The aggregates have a complex polycrystalline sphalerite structure much more advanced than typically obtained during low-temperature synthesis or observed in other modern occurrences. Platy highly-disordered radially-aggregated submicrometre crystals develop within the time constraints of several decades in the cold (~15°C) and acid (pH 3.4-4.4) peat. The less abundant Pb sulfides occur as submicron cube-like crystals between ZnS or as flat irregular or square patches on plant root macrofossils. All PbS are crystalline and defect-free. Pb ion complexation with dissolved and solid organic matter is probably responsible for the low number and equilibrium shape of PbS crystals. Iron is absent in the authigenic sulfide mineralization and occurs entirely as organically bound ferric iron (Fe3+), as revealed by Mossbauer spectroscopy. The different affinity of metals to organic matter enhances the precipitation of Zn and Cd as sulfides over Pb and Fe. Our findings demonstrate that human activities lead to the formation of near-surface stratiform metal sulfide accumulations in peat, and the polluted sites can be of use to understand and reconstruct ancient ore deposits' genesis and mechanisms of formation.
description: with supplementary material
Strong interference effects in the resonant Auger decay of atoms induced by intense X-Ray fields
Creators: name: Demekhin, Philipp V
name: Cederbaum, Lorenz S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: The theory of resonant Auger decay of atoms in a high intensity coherent X-ray pulse is presented. The theory includes the coupling between the ground state and the resonance due to an intense X-ray pulse, taking into account the decay of the resonance and the direct photoionization of the ground state, both populating the final ionic states coherently. The theory also considers the impact of the direct photoionization of the resonance state itself which typically populates highly-excited ionic states. The combined action of the resonant decay and of the direct ionization of the ground state in the field induces a non-hermitian time-dependent coupling between the ground and the 'dressed' resonance stats. The impact of these competing processes on the total electron yield and on the 2s$^2$2p$^{4}(^1\mathrm{D})$3p $^2$P spectator and 2s$^1$2p$^{6}$ $^2$S participator Auger decay spectra of the Ne 1s$\to$3p resonance is investigated. The role of the direct photoionization of the ground state and of the resonance increases dramatically with the field intensity. This results in strong interference effects with distinct patterns in the electron spectra, different for the participator and spectator final states.
description: 31 pages, 6 figures
Evaluation of methods to generate substituted tetrahydroxanthone ring systems : DMAP promoted cycloisomerizations
Creators: name: Castillo Contreras, Emmanuel Benigno
Publisher: name: University of British Columbia
Year: 2015

description: This dissertation presents investigations on the synthesis of polyoxygenated tetrahydroxanthone ring systems. Chapter 1 provides a brief overview of the family of naturally occurring compounds called xanthones. The classification, isolation, biological properties and the synthetic approaches to this family of compounds is included. Because the work of this dissertation was inspired by the tetrahydroxanthone unit embedded in simaomicin α (1.1), a detailed review of the synthetic methods available to access tetrahydroxanthone units is presented. Chapter 2 describes eight synthetic approaches that were investigated to construct substituted tetrahydroxanthones. A stereospecific intramolecular [3+2] dipolar cycloaddition of nitrile oxides resulted in the synthesis of novel fused tetracyclic isoxazolines, tetracyclic isoxazoles, and aminotetrahydroxanthones. An intramolecular hydroacylation promoted by N-heterocyclic carbenes produced substituted tetrahydroxanthones and hexahydroxanthones. Chapter 3 describes the successful synthesis of polyoxygenated tetrahydroxanthones through a 4-dimethyl- aminopyridine-promoted cycloisomerization of o-alkynoylphenol derivatives. It is proposed that the cycloi- somerization is initiated by the 1,4-addition of DMAP, followed by either a Morita-Baylis-Hillman-type aldol reaction, or deprotonation of the phenol. However, the actual mechanism remains unknown. The cycloisomerization of o-alkynoylphenol derivatives was useful in the synthesis of 1,4,5-trioxygenated or 1,5- dioxygenated tetrahydroxanthones with variable substituents at position 7. The diastereoselectivity of the reaction modestly favoured the trans-isomer.
Gamma Radiation Measurements and Dose Rates in Commonly Used Building Materials in Cyprus
Creators: name: Michael, F.
name: Tsertos, H.
name: Parpottas, Y.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Medical Physics (physics.med-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: A first comprehensive study is presented on radioactivity concentrations and dose rates in 87 commonly used materials, manufactured or imported in Cyprus, for building purposes. The natural radioactivity of K-40, Th-232, U-238 and Ra-226 is determined using high-resolution gamma ray spectroscopy. The respective dose rates and the associated radiological effect indices are also calculated. A comparison of the measured specific activity values with the corresponding world average values shows that most of them are below the world average activity values. The annual indoor effective dose rates received by an individual from three measured imported granites and four measured imported ceramics are found to be higher than the world upper limit value of 1 mSv y-1. Hence, these materials should have a restricted use according to their corresponding calculated activity concentration index values and the related EC 1999 guidelines.
description: 17 pages including 2 tables and 3 figures; Accepted by Radiation Protection Dosimetry
Characterization and cloning of suppressor of chs3-2D in Arabidopsis
Creators: name: Zhu, Chipan
Publisher: name: University of British Columbia
Year: 2015

description: Plant innate immunity depends on the function of a large number of intracellular immune receptor proteins, the majority of which are structurally similar to mammalian NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN (NOD)-LIKE RECEPTOR (NLR) proteins. CHILLING SENSITIVE 3 (CHS3) encodes an atypical Toll/Interleukin 1 Receptor (TIR)-type NLR protein with an additional Lin-11, Isl-1 and Mec-3 (LIM) domain at its C terminus. The gain-of-function mutant allele chs3-2D exhibits severe dwarfism and constitutively activated defense responses, including enhanced resistance to virulent pathogens, high PATHOGENESIS-RELATED (PR) gene expression, and salicylic acid accumulation. To search for novel regulators involved in the CHS3-mediated immune signaling pathway, we conducted suppressor screens in the chs3-2D and chs3-2D pad4-1 genetic backgrounds. Alleles of sag101 and eds1-90 were isolated as complete suppressors of chs3-2D, and alleles of sgt1b were isolated as partial suppressors of chs3-2D pad4-1. This suggests that SAG101, EDS1-90, and SGT1b are all positive regulators of CHS3-mediated defense signaling. Additionally, the TIR-type NLR-encoding CSA1 locus located in the Arabidopsis genome adjacent to CHS3 was found to be required for CHS3-mediated signaling. CSA1 is located 3.9kb upstream of CHS3 and is transcribed in the opposite direction. Altogether, these data illustrate the distinct genetic requirements for CHS3-mediated defense signaling.
Supplementary Material from Temperature adaptation and its impact on the shape of performance curves in Drosophila populations
Creators: name: Alruiz, José M.
name: Peralta-Maraver, Ignacio
name: Bozinovic, Francisco
name: Santos, Mauro
name: Rezende, Enrico L.
Publisher: name: The Royal Society
Year: 2023
Subjects: subject: Environmental Science
subject: Ecology
subject: FOS: Biological sciences

description: Document with supplementary figures and tables of the study.
YOSH OILALARDA NIKOHDAGI QIYINCHILIKLAR VA RUHIY SALOMATLIKNI SAQLASHNING IJTIMOIY-PSIXOLOGIK ASOSLARI
Creators: name: Baratov, Nasriddin
Publisher: name: Zenodo
Year: 2025

description: Yosh oilalarga nikohdagi qiyinchiliklar va ruhiy salomatlikni saqlash uchun oila quruvchi yoshlarning ruhiy salomatliklarini qo'llab-quvvatlash hamda ijtimoiy va psixologik yordam ko’rsatish zarur. Mazkur maqolada yosh oilalarning nikohdagi qiyinchiliklar va ruhiy salomatlikni saqlashning asoslari  to’g’risida fikr yuritilgan.
Continuous dependence on parameters for second order discrete BVP's
Creators: name: Galewski, Marek
name: Głab, Szymon
Publisher: name: arXiv
Year: 2011
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: Using min-max inequality we investigate the existence of solutions and thier dependence on parameters for some second order discrete boundary value problem. The approach is based on variational methods and solutions are obtained as saddle points to the Euler action functional.
description: This preprint has been submitted for publication
Clero y mujer en el siglo XIX. Vida y obra de Agustín Rivera y Sanromán
Creators: name: Arcocha, Rosa María Spinoso
Publisher: name: Lusitania Sacra
Year: 2015

description: El artículo propone una lectura, desde la perspectiva de la historia de las mujeres y de género, de la vida y la obra del cura mexicano don Agustín Rivera y Sanromán. Más precisamente de las obras dedicadas a la educación femenina. Responde a la problemática sobre lo que significaba ser un cura liberal en el México decimonónico, y qué autoridad intelectual o experiencia empírica podría tener para opinar sobre ellas.
description: Lusitania Sacra, n. 30 (2014): Catecismo e Liberalismo em Portugal e no México
Safety behaviours in generalized anxiety disorder : a clinical adult sample and a community youth sample
Creators: name: Baker, Heather Victoria
Publisher: name: University of British Columbia
Year: 2015

description: Anxiety disorders are the most common mental health problem, affect individuals across the lifespan, and cause significant impairment and distress in a variety of life domains. Safety behaviour use has been identified as contributing to the maintenance of anxiety. The reduction of safety behaviours is a component of several adult-focused Cognitive Behavioural Therapies for anxiety. Safety behaviour use is discussed in the literature specific to individual anxiety disorders. Currently, there are few psychometrically sound measures of safety behaviours available to researchers and clinicians. The few available safety behaviour measures are associated with Social Phobia (SoP) and Panic Disorder. Few studies have examined safety behaviours associated with Generalized Anxiety Disorder (GAD). This study is composed of two separate studies : Study 1 evaluated the psychometric properties of a measure of GAD-associated safety behaviours, the Generalized Safety Behaviour Scale (GSBS), in an adult sample diagnosed with Generalized Anxiety Disorder (GAD; n = 36) compared with adults with Social Phobia (SoP; n = 34) and with non-anxious controls (n = 38). The GSBS demonstrated strong internal consistency and displayed convergent validity with measures of worry and intolerance of uncertainty. Two underlying factors were identified. Construct validity of the GSBS was further assessed through one-way ANOVAs revealing that participants with GAD engaged in more frequent GAD-associated safety behaviour use than those with SoP or no anxiety. Study 2 contributed to further psychometric investigation of the GSBS and explored safety behaviour use by youth in a community sample (N = 175). The GSBS demonstrated strong internal consistency, and good convergent validity. Two underlying factors were identified. Linear regression analysis revealed that youth with high levels of anxiety engaged in more frequent use of safety behaviours. A MANOVA analysis, grouping youth into low/moderate and at-risk/clinical levels of anxiety, revealed that the at-risk/clinical group endorsed more frequent use of safety behaviours. Implications include a discussion of the benefits of using safety behaviours to help inform treatment sessions, the importance of developing psychometrically sound measures of safety behaviours, and the need to examine safety behaviour use in youth.
Replication package: Empirical Comparison of Black-box Test Case Generation Tools for RESTful APIs
Creators: name: Corradini, Davide
name: Zampieri, Amedeo
name: Pasqua, Michele
name: Ceccato, Mariano
Publisher: name: Zenodo
Year: 2021
Subjects: REST API testing

description: The replication package for the experiment conducted in the paper "Empirical Comparison of Black-box Test Case Generation Tools for RESTful APIs" by Davide Corradini, Amedeo Zampieri, Michele Pasqua and Mariano Ceccato. The dockerized REST API case studies are available in this repository: https://github.com/SeUniVr/api_case_studies
RODRIGUES, Mário Rui Simões; NETO, Margarida Sobral – Informações paroquiais e História Local: a Diocese de Coimbra (século XVIII). Coimbra: Palimage; CHSC, 2012. 283 p. ISBN 978-989-703-056-7
Creators: name: Francisco, Elisabete Correia Campos
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
Diffusion and criticality in undoped graphene with resonant scatterers
Creators: name: Ostrovsky, P. M.
name: Titov, M.
name: Bera, S.
name: Gornyi, I. V.
name: Mirlin, A. D.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A general theory is developed to describe graphene with arbitrary number of isolated impurities. The theory provides a basis for an efficient numerical analysis of the charge transport and is applied to calculate the minimal conductivity of graphene with resonant scatterers. In the case of smooth resonant impurities conductivity grows logarithmically with increasing impurity concentration, in agreement with renormalization group analysis for the symmetry class DIII. For vacancies (or strong on-site potential impurities) the conductivity saturates at a constant value that depends on the vacancy distribution among two sublattices as expected for the symmetry class BDI.
description: 4 pages, 2 figures
Multi-Scale Iterative Refinement Network for RGB-D Salient Object Detection
Creators: name: Liu, Ze-yu
name: Liu, Jian-wei
name: Zuo, Xin
name: Hu, Ming-fei
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: The extensive research leveraging RGB-D information has been exploited in salient object detection. However, salient visual cues appear in various scales and resolutions of RGB images due to semantic gaps at different feature levels. Meanwhile, similar salient patterns are available in cross-modal depth images as well as multi-scale versions. Cross-modal fusion and multi-scale refinement are still an open problem in RGB-D salient object detection task. In this paper, we begin by introducing top-down and bottom-up iterative refinement architecture to leverage multi-scale features, and then devise attention based fusion module (ABF) to address on cross-modal correlation. We conduct extensive experiments on seven public datasets. The experimental results show the effectiveness of our devised method
description: 40 pages
title: A potential role for Streptococcus gordonii in haem acquisition by Porphyromonas gingivalis
Creators: name: Brown, JL
Publisher: name: University of Liverpool Repository
Year: 2017

description: Periodontitis (PD) is an inflammatory disease arising from the dental plaque bacterial insult upon the soft periodontal tissues, resulting in damage to the tooth supporting structures. Severe forms of the disease are the main cause of tooth loss in adults, which impacts on oral health and quality of life. As control of the growth of dental plaque is only partially successful in reducing the severity of PD, a better understanding of the biochemical interactions that exist between key pathogenic inhabitants within plaque may potentially lead to the development of novel therapeutic agents that could further aid in moderating PD. Porphyromonas gingivalis, a black-pigmenting species requiring haem for growth and virulence, is identified as one of the main protagonists in the onset and maintenance of PD. P. gingivalis co-aggregates with other auxiliary pathogens in dental plaque, including Streptococcus gordonii, a member of the viridans streptococci. This study primarily investigated a potential role for S. gordonii in one of the central mechanisms utilised by P. gingivalis to acquire haem from haemoglobin (Hb) i.e., via methaemoglobin (metHb) production. It was shown herein that hydrogen peroxide production by S. gordonii was responsible for mediating the formation of metHb; the Fe(III)haem-containing Hb species utilised by P. gingivalis for haem extraction. The haem from metHb generated by S. gordonii, was more easily extracted from the protein by the HmuY haemophore of P. gingivalis, than from metHb formed by auto-oxidation. Using circular dichroism spectroscopy, it was revealed that the increased rate of HmuY-Fe(III)haem complex formation likely arose as a result of subtle changes to the Hb structure following exposure to S. gordonii-generated hydrogen peroxide. Diabetes mellitus, which is characterised by hyperglycaemia and increased levels of glycated Hb, has long been considered a risk factor of PD. The numbers of Red complex microorganisms such as P. gingivalis and viridans streptococci are also increased in the subgingival plaque of diabetic individuals. Here, it was demonstrated that the HmuY haemophore of P. gingivalis extracted haem more readily from Hb glycated in vitro than from un-glycated Hb. Mass spectroscopy of the glycated Hb indicated that the protein contained multiple glycated lysine amino acids, including Lys-90(α) and Lys-95(β) located on the same F8 helix-loops as the proximal histidines which are involved in haem-globin binding. The experimental data obtained in this study has provided evidence for two potential mechanisms through which haem availability to P. gingivalis might be enhanced. The first involves formation of metHb via streptococcal production of hydrogen peroxide. The second mechanism points to Hb glycation, a process which enhances haem extraction by HmuY. These effects may contribute to haem acquisition by P. gingivalis and might account for the increased numbers in dental plaque of diabetics.
SILVA, Ana Margarida Dias da – O Hospital e Asilo da Venerável Ordem Terceira da Penitência de S. Francisco de Coimbra. 1851-1926. Coimbra: Venerável Ordem Terceira da Penitência de S. Francisco de Coimbra, 2015. ISBN 978-989-97691-3-7
Creators: name: Pinto, Sérgio Ribeiro
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
SANTOS, João Carlos dos – Mosteiro de S. Martinho de Tibães, Projecto e compromisso. Lisboa: Uzina Books, 2012. 115 p. ISBN 978-989-8456-30-4
Creators: name: Francisco, Elisabete Correia Campos
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
PALOMO, Federico (coord.) – La memoria del mundo: clero, erudición y cultura escrita en el mundo ibérico (siglos XVI-XVIII). Madrid: Publicaciones Universidad Complutense de Madrid, 2014
Creators: name: Ceia, Sara Bravo
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
PAIVA, José Pedro – Un episcopato vigile. Portogallo, secoli XVI-XVIII. Pref. di Mario Spedicato. Trad. di Paola Nestola. Lecce: Ed. Grifo, 2013. 345, [6] p. ISBN 978-889-81752-84
Creators: name: Azevedo, Carlos A. Moreira
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
Emergence of SARS-CoV-2 escape mutations during Bamlanivimab therapy in a phase II randomized clinical trial
Creators: name: Coombs, Robert W.
name: Li, Jonathan Z.
name: Klekotka, Paul
name: Flynn, James P.
name: Eron, Joseph J.
name: Ritz, Justin
name: Sieg, Scott F.
name: Perelson, Alan S.
name: Ribeiro, Ruy M.
name: Javan, Arzhang Cyrus
name: Chew, Kara W.
name: Nirula, Ajay
name: Wohl, David A.
name: Moser, Carlee
name: Deo, Rinki
name: Parikh, Urvi M.
name: Hughes, Michael D.
name: Daar, Eric S.
name: Choudhary, Manish C.
name: Greninger, Alexander L.
name: Ke, Ruian
name: Smith, Davey M.
name: Crain, Charles R.
name: Fletcher, Courtney V.
name: Dragavon, Joan A.
name: ACTIV-2/A5401 Study Team
name: Regan, James
name: Currier, Judith S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: SARS-CoV-2 mutations that cause resistance to monoclonal antibody (mAb) therapy have been reported. However, it remains unclear whether in vivo emergence of SARS-CoV-2 resistance mutations alters viral replication dynamics or therapeutic efficacy in the immune-competent population. As part of the ACTIV-2/A5401 randomized clinical trial (NCT04518410), non-hospitalized participants with symptomatic SARS-CoV-2 infection were given bamlanivimab (700 mg or 7,000 mg) or placebo treatment. Here¸ we report that treatment-emergent resistance mutations [detected through targeted Spike (S) gene next-generation sequencing] were significantly more likely to be detected after bamlanivimab 700 mg treatment compared with the placebo group (7% of 111 vs 0% of 112 participants, P = 0.003). No treatment-emergent resistance mutations among the 48 participants who received 7,000 mg bamlanivimab were recorded. Participants in which emerging mAb resistant virus mutations were identified showed significantly higher pretreatment nasopharyngeal and anterior nasal viral loads. Daily respiratory tract viral sampling through study day 14 showed the dynamic nature of in vivo SARS-CoV-2 infection and indicated a rapid and sustained viral rebound after the emergence of resistance mutations. Participants with emerging bamlanivimab resistance often accumulated additional polymorphisms found in current variants of concern/interest that are associated with immune escape. These results highlight the potential for rapid emergence of resistance during mAb monotherapy treatment that results in prolonged high-level respiratory tract viral loads. Assessment of viral resistance should be prioritized during the development and clinical implementation of antiviral treatments for COVID-19.
SILVA, Hugo Ribeiro da – O Clero Catedralício Português e os Equilíbrios Sociais do Poder (1564-1670). Lisboa: CEHR-UCP, 2013. 291 p. ISBN 978-972-8361-49-5
Creators: name: Jana, Ernesto Alves
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
Structure formation in active networks
Creators: name: Köhler, Simone
name: Schaller, Volker
name: Bausch, Andreas R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Subcellular Processes (q-bio.SC)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: Structure formation and constant reorganization of the actin cytoskeleton are key requirements for the function of living cells. Here we show that a minimal reconstituted system consisting of actin filaments, crosslinking molecules and molecular-motor filaments exhibits a generic mechanism of structure formation, characterized by a broad distribution of cluster sizes. We demonstrate that the growth of the structures depends on the intricate balance between crosslinker-induced stabilization and simultaneous destabilization by molecular motors, a mechanism analogous to nucleation and growth in passive systems. We also show that the intricate interplay between force generation, coarsening and connectivity is responsible for the highly dynamic process of structure formation in this heterogeneous active gel, and that these competing mechanisms result in anomalous transport, reminiscent of intracellular dynamics.
Tracing the emergence of modelling routines during model-eliciting activities
Creators: name: Shahbari, Juhaina Awawdeh
name: Tabach, Michal
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Engagement in complex, challenging and multifaceted model-eliciting activities is considered helpful for preparing learners for everyday life. The current study seeks to trace the evolution of modelling routines during two model-eliciting activities. To identify how these routines emerged and evolved, we video-recorded a group of five prospective teachers as they worked on two model-eliciting activities. We then transcribed the recordings and analysed the prospective teachers’ discussion using the lens of learning as routinization. Specifically, in the participants’ work on the two model-eliciting activities, we identified three routines that emerged and evolved during their discussion. The main routine focused on integrating all the components provided to create a model. The other routines entailed assigning values to numerical and qualitative data.
The Variational Calculus on Time Scales
Creators: name: Torres, Delfim F. M.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 49K05, 39A12, 34N05

description: The discrete, the quantum, and the continuous calculus of variations, have been recently unified and extended by using the theory of time scales. Such unification and extension is, however, not unique, and two approaches are followed in the literature: one dealing with minimization of delta integrals; the other dealing with minimization of nabla integrals. Here we review a more general approach to the calculus of variations on time scales that allows to obtain both delta and nabla results as particular cases.
description: 15 pages; Published in: Int. J. Simul. Multidisci. Des. Optim. 4 (2010), 11--25
Cold War Needs Assessment - Report (Legacy 98-1754)
Creators: name: Williams, Courtney
Publisher: name: DoD Legacy Resource Management Program
Year: 2000
Subjects: subject: United States
valueUri: https://core.tdar.org/browse/geographic-keyword/10460/united-states
subject: Cold War
valueUri: https://core.tdar.org/browse/temporal-keyword/7288/cold-war
subject: Historic
valueUri: https://core.tdar.org/browse/culture-keyword/25/historic
subject: Department of Defense
valueUri: https://core.tdar.org/browse/other-keyword/123614/department-of-defense
subject: Historic Context
valueUri: https://core.tdar.org/browse/other-keyword/42191/historic-context
subject: Cold War properties
valueUri: https://core.tdar.org/browse/other-keyword/165921/cold-war-properties
subject: National Register of Historic Places
valueUri: https://core.tdar.org/browse/other-keyword/1572/national-register-of-historic-places
subject: Historic Properties
valueUri: https://core.tdar.org/browse/other-keyword/31316/historic-properties
subject: Historic Structures
valueUri: https://core.tdar.org/browse/other-keyword/837/historic-structures
subject: National Historic Preservation Act
valueUri: https://core.tdar.org/browse/other-keyword/46790/national-historic-preservation-act
subject: Cold War
valueUri: https://core.tdar.org/browse/other-keyword/138138/cold-war
subject: Historic Background Research
valueUri: https://core.tdar.org/browse/investigation-type/18/historic-background-research
subject: Heritage Management
valueUri: https://core.tdar.org/browse/investigation-type/24/heritage-management

description: This document is an agency-wide DoD framework for evaluating Cold War properties by reviewing methods used in 11 completed interservice Cold War building and structure evaluations.
PINTO, António Guimarães – Humanismo e Controvérsia Religiosa – Lusitanos e Anglicanos. Lisboa: Imprensa Nacional–Casa da Moeda, 2006. 3 vols. Vol. I: 314 p., ISBN 972-27-1392-2; vol. II: 763 p., ISBN 972-27-1392-2; vol. III: 539 p., ISBN 972-27-1519-4
Creators: name: Thomaz, Luís Filipe
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
Flutter instability speed of guided splined disks, with applications to sawing
Creators: name: Mohammadpanah, Ahmad
Publisher: name: University of British Columbia
Year: 2015

description: In this thesis the vibration characteristics of guided splined saws are studied, both analytically and experimentally. Significant insights into the complex dynamic behavior of guided splined saws are presented by analytical investigation of the dynamic behaviour of spinning splined disks and then by conducting idling and cutting experimental tests of guided splined saws. Cutting tests are conducted at different speeds, at critical, supercritical, and post flutter speeds of a guided splined saw. The cutting results are compared to determine the stable operation speeds for guided splined saws. For the analytical studies, the governing linear equations are derived for the transverse motion of a constant speed spinning splined disk. The disk is subjected to lateral constraints and loads. Rigid body translational and tilting degrees of freedom are included in the analysis of total motion of the spinning disk. Also considered in the analyses are applied conservative in-plane edge loads at the outer and inner boundaries. The numerical solution of these equations is used to investigate the effect of the loads and constraints on the natural frequencies, critical speeds, and stability of the spinning disk. The sensitivity of the eigenvalues of the splined spinning disk to the in-plane edge loads is analyzed by taking the derivative of the spinning disk’s eigenvalues with respect to the applied loads. This analysis contains an evaluation of the energy transfer from the applied loads to the disk vibrations and is used to examine the role of critical system components in the development of instability. Experimental results are presented that support the validity of the analysis. The experimental results indicate that flutter instability occurs at speeds when a backward travelling wave of a mode meets a reflected wave of a different mode. The maximum stable operating speed of the rotating splined disk is defined as the initiation of flutter. Flutter instability speeds of splined saws of various sizes were computed and verified experimentally. Then flutter speed charts of splined saws were developed which provides primary practical guide lines for sawmills to choose optimum blade diameter, eye size, blade thickness, and a stable rotation speed.
Iniciativas científicas e culturais no âmbito da história religiosa (2015)
Creators: name: Fontes, Paulo
name: Costa, Isabel
Publisher: name: Lusitania Sacra
Year: 2015

description: Lusitania Sacra, n. 32 (2015): Companhia de Jesus: Contextos Sociais e Relações de Poder (Séculos XVI a XIX)
Truck routing and scheduling for wood chip transportation to a pulp mill using Simulated Annealing
Creators: name: Nadimi, Fattane
Publisher: name: University of British Columbia
Year: 2015

description: Optimization and improvement techniques have been employed to improve truck transportation in the forest industry. Most studies in this area focus on log transportation and there is not much literature available on wood chip transportation which is distinct from log transportation in several ways : chip-truck transportation usually considers a longer planning period, requires a more complex driver scheduling, involves strict limitations on truck unloading capacity, and considers service priorities for major suppliers. The objective of this thesis is to model and improve truck transportation of wood chips to a pulp mill. To achieve this, a network that transports wood chips from a number of sawmills to a pulp mill with limited truck unloading capacity was studied and an optimization model was developed to consider wood chip production plan at supplier sawmills, transportation of wood chips and unloading at the pulp mill. A simulated annealing metaheuristic was adapted to solve the model and the results for a case study in British Columbia are presented. The results of the metaheuristic showed that the total penalties for truck waiting times could be reduced by 7 percent ($31,000) compared to solutions obtained through simulation. The results also suggested that the fleet size could be reduced by one-third of the actual fleet size used by the pulp mill. In order to explore the impact of various structural parameters on the transportation network, sensitivity and scenario analyses were used to study the impacts of fleet size, an additional truck dumper, truck types, and switch point locations for truck drivers. The results indicated that the pulp mill could reduce its fleet size and an additional truck dumper could reduce transportation costs. The study also suggested that half of the fleet should be replaced by self-unloading trucks and the investigation of the switch point locations for drivers indicated that the existing switch points were the best available options. The simulated annealing model could assist the pulp mill truck dispatchers to achieve better transportation plans. The scenario and sensitivity analysis could help the pulp mill manager to adapt the most profitable changes in the structure of the transportation network.
Doubly perturbed $S_3$ neutrinos and the $s_{13}$ mixing parameter
Creators: name: Jora, Renata
name: Schechter, Joseph
name: Shahid, M. Naeem
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We further study a predictive model for the masses and mixing matrix of three Majorana neutrinos. At zeroth order the model yielded degenerate neutrinos and a generalized ``tribimaximal" mixing matrix. At first order the mass splitting was incorporated and the tribimaximal mixing matrix emerged with very small corrections but with a zero value for the parameter $s_{13}$. In the present paper a different, assumed weaker, perturbation is included which gives a non zero value for $s_{13}$ and further corrections to other quantities. These corrections are worked out and their consequences discussed under the simplifying assumption that the conventional CP violation phase vanishes. It is shown that the existing measurements of the parameter $s_{23}$ provide strong bounds on $s_{13}$ in this model.
description: 8 pages
Shannon Entropy and Diffusion Coeffcient in Parity-Time Symmetric Quantum Walks
Creators: name: Tian, Zhiyu
name: Liu, Yang
name: Luo, Le
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Non-Hermitian topological edge states have many intriguing properties, but have so far mainly been discussed in terms of bulk-boundary correspondence. Here we propose to use a bulk property of diffusion coefficients for probing the topological states and exploring their dynamics. The diffusion coefficient is found to show unique features with the topological phase transitions driven by paritytime( PT)-symmetric non-Hermitian discrete-time quantum walks as well as by Hermitian ones, despite artificial boundaries are not constructed by inhomogeneous quantum walk. For a Hermitian system, a turning point and abrupt change appears in the diffusion coefficient when the system is approaching the topological phase transition, while it remains stable in the trivial topological state. For a non-Hermitian system, except for the feature associated to the topological transition, the diffusion coefficient in the PT-symmetric-broken phase demonstrates an abrupt change with a peak structure. In addition, the Shannon entropy of the quantum walk is found to exhibit a direct correlation with the diffusion coefficient. The numerical results presented here may open up a new avenue for studying the topological state in Non-Hermitian quantum walk systems.
Development and validity assessment of a measure of social information processing within an online context among adolescents
Creators: name: Maghsoudi, Rose
Publisher: name: University of British Columbia
Year: 2015

description: The Online Social Information Processing scale (OSIP) is a measure with 116 items that was developed based on the Social Information Processing model (SIP). The OSIP measures six social information processing skills, with a focus on how these skills are used in the face of online aggression. This goal of this study was to examine the validity of the OSIP for measuring how adolescents processed social information in online settings. After developing the items, to collect validity evidence, experts’ evaluation, as well as adolescents’ assessment through a think aloud protocol methods, was used. Evidence for validity from the item development emerged through content definition, test specification, and item editing. Evidence from expert evaluation is related to the construct of the test items in terms of alignment with the content domain and language appropriateness. Finally, evidence from student assessment came from using a think aloud protocol, which helped evaluate the language of the test items, as well as helped me understand how engaging adolescents found the measure.
The AKARI Deep Field South: Spitzer 24 and 70 micron Observations, Catalogs and Counts
Creators: name: Clements, D. L.
name: Bendo, G.
name: Pearson, C.
name: Khan, Sophia A.
name: Matsuura, S.
name: Shirahata, M.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The AKARI Deep Field South (ADF-S) is a ~12 sq. deg. region near the South Ecliptic Pole that has been observed with deep scans in the far-infrared by the AKARI satellite. As such it is becoming one of the key extragalactic survey fields. We here present complementary observations of the ADF-S conducted by the Spitzer Space Telescope at wavelengths of 24 and 70 micron. We extract source catalogs at each of these wavelengths reaching depths of ~ 0.2mJy at 24 micron and ~ 20mJy at 70 micron. We also apply an K-to-24 micron colour criterion to select objects with galaxy-like colours in the 24 micron survey. Completeness corrections as a function of flux density are derived for both catalogs by injecting artificial sources of known flux density into the maps, and we find that our surbveys are 50% complete at 0.26mJy and 24mJy at 24 and 70 micron respectively. We can thus produce number counts as a function of flux density for the ADF-S at 24 and 70 micron. These are combined with existing literature counts and compared to four different number count models derived from galaxy evolution models. One complicating factor for the ADF-S counts is the presence of a foreground galaxy cluster at z=0.04 in the field. We examine the ranges of flux densities to which this cluster might make a contribution to the counts and find hints that the 24 micron luminosity function of the cluster galaxies might be enhanced above that of field galaxies. Full catalogs for these ADF-S Spitzer surveys at 24 and 70 micron are made available as part of this paper.
description: 13 pages, 11 figures, accepted for publication in MNRAS
Soliton complexity in the damped-driven nonlinear Schrödinger equation: stationary, periodic, quasiperiodic complexes
Creators: name: Barashenkov, I. V.
name: Zemlyanaya, E. V.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Stationary and oscillatory bound states, or complexes, of the damped-driven solitons are numerically path-followed in the parameter space. We compile a chart of the two-soliton attractors, complementing the one-soliton attractor chart.
description: 12 pages, 7 figures