cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
How fair is the AFL draw?
Creators: name: Clarke, Stephen
Publisher: name: Swinburne
Year: 2024

description: This paper discusses the fairness of the AFL home and way draw. The use of a linear model to estimate team ability and home advantage is shown. The degree of difficulty inherent in the draw is estimated by calculating the average standard of the opposition. However an extra term is necessary to allow for better teams playing weaker than average opponents. The technique is demonstrated using final ladder position as a measure of team ability. The draw difficulty is shown to be different for different teams, and the bias does not even out over the years. Another method compares the expected final ladder position under the actual draw with the fair position. The efficiency of the draw to reward better terms with higher final ladder position is estimated via a simulation. This shows the huge amount of variability due to randomness inherent in the League draw.
Tidal disruption of the magellanic clouds by the milky way
Creators: name: Putman, M. E.
name: Gibson, B. K.
name: Staveley-Smith, L.
name: Banks, G.
name: Barnes, D. G.
name: Bhatal, R.
name: Disney, M. J.
name: Ekers, R. D.
name: Freeman, K. C.
name: Haynes, R. F.
name: Henning, P.
name: Jerjen, H.
name: Kilborn, Virginia
name: Koribalski, B.
name: Knezek, P.
name: Malin, D. F.
name: Mould, Jeremy
name: Oosterloo, T.
name: Price, R. M.
name: Ryder, S. D.
name: Sadler, E. M.
name: Stewart, I.
name: Stootman, F.
name: Vaile, R. A.
name: Webster, R. L.
name: Wright, A. E.
Publisher: name: Swinburne
Year: 2024

description: Interactions between galaxies are common, and influence physical properties such as the global morphology and star-formation rate1 (Hubble type). Galaxies can interact in many different ways: they can merge together; they can pass through each other, with gas being stripped from the smaller of the two and compressed in the larger; and they can interact gravitationally (including, for example, tides in clusters). The relative importance of these mechanisms is often not clear, as the strength of each depends on poorly known parameters such as the density, extent and nature of the dark-matter haloes that surround galaxies3. A nearby example of a galaxy interaction where the mechanism is controversial is that between our Galaxy and two of its neighbours, the Magellanic Clouds. Here we present the results of an atomic-hydrogen survey that help to elucidate this mechanism. Our data reveal a new stream of gas that lies in the opposite direction to the trailing Magellanic Stream and leads the motion of the Clouds. The existence of both leading and trailing streams supports a gravitational interaction whereby the streams are torn from the bodies of the Magellanic Clouds by tidal forces.
The influence of sample size, effect size, and percentage of DIF items on the performance of the Mantel-Haenszel and logistic regression DIF identification procedures.
Creators: name: Kennedy, Michael.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Education, Tests and Measurements.

description: The frequent use of standardized tests for admission, advancement, and accreditation has increased public awareness of measurement issues, in particular, test and item bias. The logistic regression (LR) and Mantel-Haenszel (MH) procedures are relatively new methods of detecting item bias or differential item functioning (DIF) in tests. In only a few studies has the performance of these two procedures been compared. In the present study, sample size, effect size, and percentage of DIF items in the test were manipulated in order to compare detection rates of uniform DIF by the LR and MH procedures. Simulated data, with known amounts of DIF, were used to evaluate the effects of these variables on DIF detection rates. In detecting uniform DIF, the LR procedure had a slight advantage over the MH procedure at the cost of increased false positive rates. P-value difference was definitely a more accurate measure of the amount of DIF than b value difference. (Abstract shortened by UMI.)
Supplementary document for A study on effects of terahertz radiation on gene networks of Escherichia coli by means of fluorescent biosensors - 4745039.pdf
Creators: name: Serdyukov, Danil
name: Goryachkovskaya, Tatiana
name: Mescheryakova, Irina
name: Bannikova, Svetlana
name: Kuznetsov, Sergei
name: Cherkasova, Olga
name: Popik, Vasiliy
name: Peltek, Sergey
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplemental Document
Snakebite Envenoming – A Combined Density Equalizing Mapping and Scientometric Analysis of the Publication History
Creators: name: Groneberg, David A.
name: Geier, Victoria
name: Klingelhöfer, Doris
name: Gerber, Alexander
name: Kuch, Ulrich
name: Kloft, Beatrix
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Estimates suggest that more than 25,000 to 125,000 people die annually from snakebite envenomation worldwide. In contrast to this major disease burden, thorough bibliometric studies do not exist so far that illustrate the overall research activity over a long time span. Therefore, the NewQIS-platform conducted an analysis on snakebite envenoming using the Thomson Reuters database Web of Science. To determine and assess changes regarding the scientific activities and to specifically address the more recent situation we analyzed two time intervals (t). During the first time interval from 1900 to 2007 (t1) 13,015 publications (p) were identified. In the following period (2008–2016 = t2) 4,982 publications were identified by the same search strategy. They originate from 114 (t1) respectively 121 countries (t2), with the USA (p = 3518), Brazil (p = 1100) and Japan (p = 961) being most productive in the first period, and the USA (p = 1087), Brazil (p = 991) and China (p = 378) in the second period, respectively. Setting the publication numbers in relation to GDP/capita, Brazil leads with 92 publications per 10,000 Int$GDP/capita, followed by India with 79 publications per 10000 Int$GDP/capita (t1). Comparing the country’s publication activity with the Human Development Index level indicates that the majority of the publications is published by highly developed countries. When calculating the average citation rates (citations per published item = CR) mainly European countries show the highest ranks: From 1900–2007 Sweden ranks first with a CR = 27, followed by the Netherlands (CR = 24.8), Switzerland (CR = 23), Spain, Austria and the USA (CR = 22). From 2008 to 2016 the highest rate achieves Switzerland with a value of 24.6, followed by Belgium (CR = 18.1), Spain (CR = 16.7), Costa Rica (CR = 14.9) and Netherlands (CR = 14). Compared with this, the USA was placed at rank 13 (CR = 9,5). In summary, the present study represents the first density-equalizing map projection and in-depth scientometric analysis of the global research output on snakebites and its venoms. So it draws a sketch of the worldwide publication architecture and indicates that countries with a high incidence of snakebites and a low economical level still need to be empowered in carrying out research in this area.
How does availability of county-level healthcare services shape terminal decline in well-being?
Creators: name: Ram, Nilam
name: Vogel, Nina
name: Goebel, Jan
name: Wagner, Gerd G.
Publisher: name: My University
Year: 2017
Subjects: Landkreis

description: Both lifespan psychology and life course sociology highlight that contextual factors influence individual functioning and development. In the current study, we operationalize context as county-level care services in inpatient and outpatient facilities (e.g., number of care facilities, privacy in facilities) and investigate how the care context shapes well-being in the last years of life. To do so, we combine 29 waves of individual-level longitudinal data on life satisfaction from now deceased participants in the nationwide German Socio-Economic Panel Study (N = 4557; age at death: M = 73.35, SD = 14.20; 47% women) with county-level data from the Federal Statistical Office. Results from three-level growth models revealed that having more inpatient care facilities, more employees per resident, and more staff in administration are each uniquely associated with higher late-life well-being, independent of key individual (age at death, gender, education, disability) and county (affluence, demographic composition) characteristics. Number of employees in physical care, residential comfort, and flexibility and care indicators in outpatient institutions were not found to be associated with levels or change in well-being. We take our results to provide empirical evidence that some contextual factors shape well-being in the last years of life and discuss possible routes how local care services might alleviate terminal decline.
Evaluation of A Concentrated Preterm Formula as a Liquid Human Milk Fortifier in Preterm Babies at Increased Risk of Feed Intolerance
Creators: name: Pillai, Anish
name: Albersheim, Susan
name: Matheson, Julie
name: Lalari, Vikki
name: Wei, Sylvia
name: Innis, Sheila M.
name: Elango, Rajavel
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: There are concerns around safety and tolerance of powder human milk fortifiers to optimize nutrition in preterm infants. The purpose of this study was to evaluate the tolerance and safety of a concentrated preterm formula (CPF) as a liquid human milk fortifier (HMF) for premature infants at increased risk of feeding intolerance. We prospectively enrolled preterm infants over an 18-month period, for whom a clinical decision had been made to add CPF to human milk due to concerns regarding tolerance of powder HMF. Data on feed tolerance, anthropometry, and serum biochemistry values were recorded. Serious adverse events, such as mortality, necrotizing enterocolitis (NEC), and sepsis, were monitored. A total of 29 babies received CPF fortified milk during the study period. The most common indication for starting CPF was previous intolerance to powder HMF. Feeding intolerance was noted in 4 infants on CPF. The growth velocity of infants was satisfactory (15.9 g/kg/day) after addition of CPF to feeds. The use of CPF as a fortifier in preterm babies considered at increased risk for feed intolerance seems well tolerated and facilitates adequate growth. Under close nutrition monitoring, this provides an additional option for human milk fortification in this challenging subgroup of preterm babies, especially in settings with limited human milk fortifier options.
Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes
Creators: name: Riegger, Jana
name: Brenner, Rolf E.
Publisher: name: Universität Ulm
Year: 2023
Subjects: subject: Phenotypical alteration
subject: DDC 150 / Psychology
subject: DDC 570 / Life sciences
subject: Osteoarthritis
subject: Chondrocytes
subject: Phenotype
subject: Osteoarthritis
subject: Connective Tissue Growth Factor
subject: Phänotyp

description: Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilagehomeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis(OA). However, the underlying mechanisms of phenotypical alteration in chondrocytes areincompletely understood. Here, we provide evidence that disruption of the intracellularvimentin network and consequent phenotypical alteration in human chondrocytes results in anexternalization of the intermediate filament. The presence of the so-called cell surfacevimentin (CSV) on chondrocytes was associated with the severity of tissue degeneration inclinical OA samples and was enhanced after mechanical injury of cartilage tissue. By meansof a doxorubicine-based in vitro model of stress-induced premature senescence (SIPS), wecould confirm the connection between cellular senescence and amount of CSV. AlthoughsiRNA-mediated silencing of CDKN2A clearly reduced the senescent phenotype as well asCSV levels of human chondrocytes, cellular senescence could not be completely reversed.Interestingly, knockdown of vimentin resulted in a SIPS-like phenotype and consequentlyincreased CSV. Therefore, we concluded that the integrity of the intracellular vimentinnetwork is crucial to maintain cellular function in chondrocytes. This assumption could beconfirmed by chemically- induced collapse of the vimentin network, which resulted in cellularstress and enhanced CSV expression. Regarding its biological function, CSV was found to beassociated with enhanced chondrocyte adhesion and plasticity. While osteogenic capacitiesseemed to be enhanced in chondrocytes expressing high levels of CSV, the chondrogenicpotential was clearly compromised. Overall, our study reinforces the importance of thevimentin network in maintenance of the chondrogenic phenotype and introduces CSV as anovel membrane-bound marker of dysfunctional chondrocytes.
Flexible instruments for a snake-like robot
Creators: name: Schmitz, Andreas
Publisher: name: Imperial College London
Year: 2020

description: Minimally Invasive Surgery (MIS) is a widely adopted technique due to the many advantages it holds for patients, e.g., reductions in healing times. In MIS one procedure within many is using a snakelike robot for scarless endoscopic surgery, such as gastrointestinal endoscopic surgery. In this type of surgery, the snake-like robot is inserted through a natural orifice and is directed towards a chosen surgical site. Once the robot is in place, small robotic instrument arms are deployed from the head of the robot to perform surgical tasks, e.g., cutting or suturing. These instruments need to have a small diameter of approximately ⌀3-4mm such that they can be inserted through working channels or biopsy ports within the snake-like robot. Multiple designs of surgical instruments have been proposed in research, such as concentric tube robots, soft robots or rigid-links tendonactuated robots. On the instrument tips grippers to hold the tissue, small scissors, or knives can be mounted. Other more special types of instruments are available as well. Surgeons can control the instruments remotely and see them through a camera which is mounted on the tip of the robot. This thesis is part of the the i2Snake project which developed a homonymous snake-like robot with a length of 36.6cm and a diameter of 16mm. The length can be adapted by adjusting the length of the passive part to adapt to different procedures. In the scope of this thesis robotic instrument arms for the i2Snake robot were developed. Prototypes of these arms were built with a diameter of ⌀4mm and ⌀3mm. Similar instruments with a diameter of ⌀5mm and above were published before. For the new prototypes a rolling gear joint was developed to improve the accuracy of the arm and a gripper with an embedded distal roll. A shape sensor prototype was developed which only needs 3 receiving fibers. The 3mm instrument was optimised with a newly developed optimisation algorithm. To combine the developed approaches, a control was implemented which incorporates a reinforcement learning inverse kinematics and a mathematical model to compensate for backlash and joint coupling. The 4mm instrument with 7 DOF can bend up to 72° in each joint and has a rolling motion of 165.65°. The final 3mm instrument has 5 DOF, including a prismatic joint, and can bend up to 82° in each joint and roll 5for 90°. The learned inverse kinematics is more precise in position and orientation error than the common Damped least-squares Jacobian pseudo-inverse, mainly because it has no problems with joint limits or complex situations. Using the proposed compensation methods, the backlash was significantly reduced so that the overall average positioning error was improved to 1.49mm.
Mediators and mechanisms of change in internet- and mobile-based interventions for depression: A systematic review
Creators: name: Domhardt, Matthias
name: Steubl, Lena
name: Boettcher, Johanna
name: Buntrock, Claudia
name: Karyotaki, Eirini
name: Ebert, David D.
name: Cuijpers, Pim
name: Baumeister, Harald
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: Digital mental health
subject: Psychotherapy process research
subject: Mechanism of change
subject: Common mental disorder
subject: DDC 150 / Psychology
subject: DDC 610 / Medicine & health
subject: Internet-based intervention; Trends
subject: Depressive disorder; Therapy
subject: Intervention
subject: Depression

description: The efficacy of Internet- and mobile-based interventions (IMIs) for depression in adults is well established. Yet, comprehensive knowledge on the mediators responsible for therapeutic change in these interventions is pending. Therefore, we conducted the first systematic review on mediators in IMIs for depression, investigating mechanisms of change in interventions with different theoretical backgrounds and delivery modes (PROSPERO CRD42019130301). Two independent reviewers screened references from five databases (i.e., Cochrane Library, Embase, MEDLINE/PubMed, PsycINFO and ICTRP), selected studies for inclusion and extracted data from eligible studies. We included 26 RCTs on mediators in IMIs for depression (6,820 participants), rated their risk of bias and adherence to methodological quality criteria for psychotherapy process research. Primary studies examined 64 mediators, with cognitive variables (e.g., perceived control, rumination or interpretation bias) being the largest group of both examined (m=28) and significant mediators (m=22); followed by a range of other mediators, including mindfulness, acceptance and behavioral activation. Our findings might contribute to the empirically-informed advancement of interventions and mental health care practices, enabling optimized treatment outcomes for patients with depression. Furthermore, we discuss implications for future research and provide methodological recommendations for forthcoming mediation studies with more pertinent designs, allowing for inferences with higher causal specificity.
Supplementary document for A study on effects of terahertz radiation on gene networks of Escherichia coli by means of fluorescent biosensors - 4745039.pdf
Creators: name: Serdyukov, Danil
name: Goryachkovskaya, Tatiana
name: Mescheryakova, Irina
name: Bannikova, Svetlana
name: Kuznetsov, Sergei
name: Cherkasova, Olga
name: Popik, Vasiliy
name: Peltek, Sergey
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplemental Document
On incremental global update support in cooperative database systems
Creators: name: Liu, Chengfei
name: Zhou, Xiaofang
name: Cao, Jinli
name: Lin, Eshed Xuemin
Publisher: name: Swinburne
Year: 2024

description: OzGateway is a cooperative database system designed for integrating heterogeneous existing information systems into an interoperable environment. It also aims to provide a gatewway for legacy information system migration. This paper summarises the problems and results of multidatabase transaction management research. In supporting global updates in OzGateway in an evolutionary way, we introduce a classification of multidatabase transactions and discuss the problems in each category. The architecture of OzGateway and the design of the global transaction manager and servers are presented.
Frontal corpus callosum alterations in progressive supranuclear palsy but not in Parkinson's disease
Creators: name: Roßkopf, Johannes C.
name: Müller, Hans-Peter
name: Huppertz, Hans-Jürgen
name: Ludolph, Albert C.
name: Pinkhardt, Elmar Hans
name: Kassubek, Jan Rainer
Publisher: name: Universität Ulm
Year: 2014
Subjects: subject: Fractional anisotropy
subject: Parkinsonian syndromes
subject: Parkinson disease
subject: Diffusion tensor imaging
subject: Magnetic resonance imaging
subject: Anisotropy
subject: Parkinson-Krankheit
subject: Diffusionsgewichtete Magnetresonanztomografie
subject: Anisotropie

description: Background: Frontal lobe involvement is considered a clinical and magnetic resonance imaging (MRI) feature in later stages of progressive supranuclear palsy (PSP). Objective: Diffusion tensor imaging (DTI) was used to investigate the integrity of frontal pathways in PSP and Parkinson's disease (PD) patients. Methods: DTI and 3-D MRI were performed in 15 PSP patients (parkinsonism subtype: n = 8; Richardson subtype: n = 7), 15 PD patients, and 18 matched controls. DTI analysis was performed in order to identify differences along frontal white matter structures including the corpus callosum (CC) and was complemented by atlas-based volumetry and planimetry. Results: Significantly reduced regional fractional anisotropy was observed for PSP patients versus controls and PSP versus PD patients, respectively, in frontal areas including the area II of the CC and bilaterally in the callosal radiation. The DTI findings correlated with frontal lobe volumes. These differences were not observed between PD patients and controls. Conclusion: DTI identified a PSP-associated microstructural alteration pattern in the frontal lobes and in the CC area II including the corresponding bilateral callosal radiation tracts that could not be identified in both control samples, supporting the prominent PSP-associated frontal involvement as a potential neuroimaging marker. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
The social construction of a torture sustaining reality: A rhetorical analysis of claims-making about terrorism as a social problem in the United States post 911
Creators: name: Doucette, Jason Francis
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Political Science, General.
subject: Sociology, Criminology and Penology.

description: This study examines how rhetoric was used to socially construct a torture sustaining reality in the United States after the September 11th terrorist attacks, by both print journalists and President George W. Bush's Administration. After the 9/11 attacks terrorism received wide attention from the media and public. As a result of these attacks, the United States began the ''war on terror" and invaded Afghanistan and later Iraq. During these invasions allegations of torture by the American military began to emerge. This study carries out a content analysis of claims about terrorism and responses to allegations of torture. This analysis is guided by the contextual social constructionist approach of Joel Best (1990) and Stanley Cohen's (2001) study of "denials". The contextual social constructionist approach of Best (1990) is the theoretical departure point for a sample drawn from the New York Times as well as a sample drawn from the Internet website for the Whitehouse during George W. Bush's tenure as President. A final sample drawn from the same Whitehouse website will be engaged through an amalgamation of Best's (1990) contextual social constructionist approach and Cohen's (2001) study of "denials". This study reveals that the construction of terrorism as a social problem aided the maintenance of a torture sustaining reality. This study further explains how rationalizations are used by a liberal government to maintain a torture sustaining reality through the use of rhetoric and denials. In addition, this study shows that a torture sustaining reality is supported through the mobilization of language that dehumanizes (the process of othering) those who stand in opposition to it. As well, this study demonstrates how the concepts of risk and moral panic also help to explain how this torture sustaining reality is maintained in a liberal state. Furthermore, this study also investigates the claim-making process. In pursuing these areas, the study illustrates how denials are rhetorically composed, or in other words what language is used and how it is used to form denials. More specifically, this study reveals how the rhetoric of denial is formed and shifts to support a torture sustaining reality during a claims-making episode. Secondly, claims-making about terrorism does not always follow the "typical" path of most claim-making about social problems. Claims-making about terrorism sometimes involves the "Rhetoric of Rectitude" and the "Rhetoric of Rationality", which can be intertwined to help predicate a torture sustaining reality, or may predominantly rely upon the "Rhetoric of Rectitude". Finally, this study alerts us to very paradoxical nature that freedom occupies in this world, and how easily the notion of freedom may be championed to justify atrocities.
Current EU research activities on combined exposure to multiple chemicals
Creators: name: Barouki, Robert
name: Brack, Werner
name: Kolossa-Gehring, Marike
Publisher: name: My University
Year: 2018

description: Humans and wildlife are exposed to an intractably large number of different combinations of chemicals via food, water, air, consumer products, and other media and sources. This raises concerns about their impact on public and environmental health. The risk assessment of chemicals for regulatory purposes mainly relies on the assessment of individual chemicals. If exposure to multiple chemicals is considered in a legislative framework, it is usually limited to chemicals falling within this framework and co-exposure to chemicals that are covered by a different regulatory framework is often neglected. Methodologies and guidance for assessing risks from combined exposure to multiple chemicals have been developed for different regulatory sectors, however, a harmonised, consistent approach for performing mixture risk assessments and management across different regulatory sectors is lacking. At the time of this publication, several EU research projects are running, funded by the current European Research and Innovation Programme Horizon 2020 or the Seventh Framework Programme. They aim at addressing knowledge gaps and developing methodologies to better assess chemical mixtures, by generating and making available internal and external exposure data, developing models for exposure assessment, developing tools for in silico and in vitro effect assessment to be applied in a tiered framework and for grouping of chemicals, as well as developing joint epidemiological-toxicological approaches for mixture risk assessment and for prioritising mixtures of concern. The projects EDC-MixRisk, EuroMix, EUToxRisk, HBM4EU and SOLUTIONS have started an exchange between the consortia, European Commission Services and EU Agencies, in order to identify where new methodologies have become available and where remaining gaps need to be further addressed. This paper maps how the different projects contribute to the data needs and assessment methodologies and identifies remaining challenges to be further addressed for the assessment of chemical mixtures. © 2018 The Authors. Published by Elsevier Ltd.
Free at last! A flexible learning tool: enhancement, engagement and empowerment
Creators: name: Savage, Theresa
name: Clulow, Val
name: Salehi, Kay
Publisher: name: Swinburne
Year: 2024

description: Web-based interactive lessons are potentially more engaging and enhance the quality of learning. This paper presents results of an online survey on the perceived experience of first year advanced and second year beginners' stream Japanese language students using a web-based learning tool. Findings indicate that collaboration by stakeholders during the learning process leads to improved approaches to achieving the optimum learning experience and outcome. Moreover, a learner-centred approach combined with appropriate learning strategies frees up the learning process, providing a positive and rewarding experience for all involved.
On the relationship of interoceptive accuracy and attention: A controlled study with depressed inpatients and a healthy cohort
Creators: name: Schultchen, Dana
name: Schneider, Carolin
name: Berberich, Götz
name: Zaudig, Michael
name: Erle, Thorsten M.
name: Pollatos, Olga
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: DDC 150 / Psychology
subject: Depressive disorder
subject: Interoception
subject: Attention
subject: Depression
subject: Interozeption
subject: Aufmerksamkeit

description: Objective: Previous research has shown reduced interoceptive accuracy (IAcc) in depression. Attention deficit represents a key symptom of depression. Moreover, IAcc is positively correlated with attention. There is no study that investigates the effect of depression on IAcc and attention. The aim of this study is to examine the mediating effect of IAcc on depression and attention. Methods: Thirty-six depressed patients from the Psychosomatic Clinic inWindach were matched with 36 healthy controls according to age and sex and were assessed at Ulm University. All participants completed the Beck Depression Inventory-II, the heartbeat perception task to examine IAcc, and the d2 test assessing selective attention. Results: Depressed patients showed attention deficits—both for general visual attention and IAcc—compared to healthy controls. The mediation analyses revealed that the relationship between depression and attention is not mediated via IAcc. Furthermore, depression predicts IAcc and attention, but these effects are direct and largely unaffected by the respective other variable. Discussion: The results of the present study highlight both interoceptive as well as attention deficits in depressed patients. No clear mediation between these variables could be shown in this study. More elaborative research is needed to clarify whether different approaches to improve IAcc are effective for these deficits in depressed patients and could therefore be of importance as an additional aspect of therapy in depression.
Supplementary document for A comprehensive study of end-to-end Unet-based reconstruction algorithm for photoacoustic imaging - 4745697.pdf
Creators: name: Feng, Jinchao
name: Deng, Jianguang
name: Li, Zhe
name: Sun, Zhonghua
name: Dou, Huijing
name: Jia, Kebin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplemental details to manuscript
La reconnaissance de formes bidimensionnelles chez le pigeon: Le role de la position et de l'orientation des composantes
Creators: name: Landry, France
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Psychology, Experimental.

description: La presente etude propose premierement une recension des ecrits en lien avec les processus impliques dans la reconnaissance des formes et, plus specifiquement, traite du role de la position et de l'orientation dans la reconnaissance de formes en deux dimensions chez le pigeon. Subsequemment, trois experiences ayant comme objectif de determiner la valeur et l'utilisation de ces dimensions spatiales sont presentees. Ces trois experiences proposent une procedure similaire ou il y a tout d'abord une periode d'apprentissage d'une discrimination entre deux stimuli comportant des dimensions differentes et ensuite un jugement de similarite entre ces stimuli et de nouveaux stimuli presentant des transformations des dimensions spatiales utilisees. Le choix des pigeons est mesure par la frequence de reponses a ces nouveaux stimuli. La premiere experience met en conflit l'information de la position et de l'orientation des composantes dans une tache de jugement de similarite. Les resultats revelent que l'information de la position est predominante sur celle de l'orientation. La deuxieme experience contraste l'information de la position et celle de la forme geometrique et tente de determiner laquelle de ces informations detient un controle sur la similarite percue lors de modifications de ces dimensions. Les resultats demontrent que l'information de la position est egalement predominante sur la forme geometrique. La troisieme experience s'attarde a l'organisation spatiale interne des composantes en utilisant des stimuli produisant une confusion chez plusieurs especes, soit l'image miroir gauche-droite et la transposition simple des composantes de la gauche et de la droite. Les resultats attestent que non seulement les pigeons n'ont pas confondu les differentes transformations, mais que, contrairement aux recherches anterieures et en concordance avec les resultats des deux premieres experiences, ils ont porte une attention particuliere a la position de chaque composante. Finalement, la discussion generale propose certaines explications theoriques et contraste les resultats obtenus aux theories de reconnaissance existantes.
Clinical significance in pediatric oncology randomized controlled treatment trials: a systematic review
Creators: name: Howard, A. Fuchsia
name: Goddard, Karen
name: Rassekh, S. Rod
name: Samargandi, Osama A.
name: Hasan, Haroon
Publisher: name: BioMed Central
Year: 2018

description: Background: Clinical significance in a randomized controlled trial (RCT) can be determined using the minimal clinically important difference (MCID), which should inform the delta value used to determine sample size. The primary objective was to assess clinical significance in the pediatric oncology randomized controlled trial (RCT) treatment literature by evaluating: (1) the relationship between the treatment effect and the delta value as reported in the sample size calculation, and (2) the concordance between statistical and clinical significance. The secondary objective was to evaluate the reporting of methodological attributes related to clinical significance. Methods: RCTs of pediatric cancer treatments, where a sample size calculation with a delta value was reported or could be calculated, were systematically reviewed. MEDLINE, EMBASE, and the Cochrane Childhood Cancer Group Specialized Register through CENTRAL were searched from inception to July 2016. Results: RCTs (77 overall; 11 and 66), representing 95 (13 and 82) randomized questions were included for non-inferiority and superiority RCTs (herein, respectively). The minority (22.1% overall; 76.9 and 13.4%) of randomized questions reported conclusions based on clinical significance, and only 4.2% (15.4 and 2.4%) explicitly based the delta value on the MCID. Over half (67.4% overall; 92.3 and 63.4%) reported a confidence interval or standard error for the primary outcome experimental and control values and 12.6% (46.2 and 7.3%) reported the treatment effect, respectively. Of the 47 randomized questions in superiority trials that reported statistically non-significant findings, 25.5% were possibly clinically significant. Of the 24 randomized questions in superiority trials that were statistically significant, only 8.3% were definitely clinically significant. Conclusions: A minority of RCTs in the pediatric oncology literature reported methodological attributes related to clinical significance and a notable portion of statistically insignificant studies were possibly clinically significance.
title: Diverse Capacities - Showcase and Immersive Exhibition
Creators: name: Ashton, Daniel
name: May, Will
name: Jahan, Aiysha
Publisher: name: University of Southampton
Year: 2024

description: The exhibitions celebrated Phase One and Two of our Diverse Capacities project through a brilliant showcase held in the Digital Humanities Hub at the University of Southampton. The eight creative practitioners involved in the project produced immersive commissions, many of which used the Igloo, the hub's 360-degree fully immersive audio-visual centre.

The day brought together the LGOs from Phase One and the creative practitioners from Phase Two, giving them the opportunity to network with each other. The commissions also provided the LGOs with insight into the practitioners' journeys and creative practice through their artwork and presentations.
Versatile Atomic Magnetometry Assisted by Bayesian Inference
Creators: name: Puebla, R.
name: Ban, Y.
name: Haase, J. F.
name: Plenio, M. B.
name: Paternostro, M.
name: Casanova, J.
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: Quantum description of light-matter interaction
subject: Quantum metrology
subject: Quantum protocols
subject: Quantum sensing
subject: Bayesian methods
subject: Microwave techniques
subject: Monte Carlo methods
subject: DDC 530 / Physics
subject: Trapped ions
subject: Quantenmetrologie
subject: Ionenfalle

description: Quantum sensors typically translate external fields into a periodic response whose frequency is then determined by analyses performed in Fourier space. This allows for a linear inference of the parameters that characterize external signals. In practice, however, quantum sensors are able to detect fields only in a narrow range of amplitudes and frequencies. A departure from this range, as well as the presence of significant noise sources and short detection times, lead to a loss of the linear relationship between the response of the sensor and the target field, thus limiting the working regime of the sensor. Here we address these challenges by means of a Bayesian inference approach that is tolerant to strong deviations from desired periodic responses of the sensor and is able to provide reliable estimates even with a very limited number of measurements. We demonstrate our method for an 171Yb+ trapped-ion quantum sensor but stress the general applicability of this approach to different systems.
SCORE: Shared care of Colorectal cancer survivors: Protocol for a randomised controlled trial
Creators: name: Jefford, Michael
name: Emery, Jon
name: Grunfeld, Eva
name: Martin, Andrew
name: Rodger, Paula
name: Murray, Alexandra M.
name: De Abreu Lourenco, Richard
name: Heriot, Alexander
name: Phipps-Nelson, Jo
name: Guccione, Lisa
name: King, Dorothy
name: Lisy, Karolina
name: Tebbutt, Niall
name: Burgess, Adele
name: Faragher, Ian
name: Woods, Rodney
name: Schofield, Penelope
Publisher: name: Swinburne
Year: 2024

description: Background: Colorectal cancer (CRC) is the most common cancer affecting both men and women. Survivors of CRC often experience various physical and psychological effects arising from CRC and its treatment. These effects may last for many years and adversely affect QoL, and they may not be adequately addressed by standard specialist-based follow-up. Optimal management of these effects should harness the expertise of both primary care and specialist care. Shared models of care (involving both the patient's primary care physician [PCP] and specialist) have the potential to better support survivors and enhance health system efficiency. Methods/design: SCORE (Shared care of Colorectal cancer survivors) is a multisite randomised controlled trial designed to optimise and operationalise a shared care model for survivors of CRC, to evaluate the acceptability of the intervention and study processes, and to collect preliminary data regarding the effects of shared care compared with usual care on a range of patient-reported outcomes. The primary outcome is QoL measured using the European Organisation for Research and Treatment of Cancer QLQ-C30 questionnaire. Secondary outcomes are satisfaction with care, unmet needs, continuity of care and health resource use. The shared care model involves replacement of two routine specialist follow-up visits with PCP visits, as well as the provision of a tailored survivorship care plan and a survivorship booklet and DVD for CRC survivors. All consenting patients will be randomised 1:1 to either shared care or usual care and will complete questionnaires at three time points over a 12-month period (baseline and at 6 and 12 months). Health care resource use data will also be collected and used to evaluate costs. Discussion: The evaluation and implementation of models of care that are responsive to the holistic needs of cancer survivors while reducing the burden on acute care settings is an international priority. Shared care between specialists and PCPs has the potential to enhance patient care and outcomes for CRC survivors while offering improvements in health care resource efficiency. If the findings of the present study show that the shared care intervention is acceptable and feasible for CRC survivors, the intervention may be readily expanded to other groups of cancer survivors. Trial registration: Australian New Zealand Clinical Trials Registry, ACTRN12617000004369p. Registered on 3 January 2017; protocol version 4 approved 24 February 2017.
title: Mycobacterium Tuberculosis y hallazgos radiológicos : año 2010 en un Área de Salud.
Creators: name: Salelles Climent, Pablo
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Infection
subject: Epidemiology
subject: Cavitation
subject: CT
subject: Digital radiography
subject: Thorax
subject: eHealth

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Describir los hallazgos radiológicos en los casos confirmados de enfermedad tuberculosa,
pulmonar y extrapulmonar en un Area de Salud . Conocer sus seculas y complicaciones...
The wealth and poverty of networks part one: networks in a space of flows
Creators: name: Friedman, Ken
Publisher: name: Swinburne
Year: 2024

description: In many senses, networks have become typical even emblematic of many kinds of processes in the world. These processes are often hailed as a step toward democracy, equality of opportunity, access to resources, and appropriate governance of the world's resources. All of these statements are reasonable. Nevertheless, networks offer no simple solutions to the world's problems. In the course of solving some problems, networks introduce challenges and problems of their own. The network society is an overlay wrapped around different kinds of societies and cultures, linking them and connecting them. The network society reshapes older societies, sometimes destroying them. This process can be seen in many ways.
Identifying Risk of Viral Failure in Treated HIV-Infected Patients Using Different Measures of Adherence: The Antiretroviral Therapy Cohort Collaboration
Creators: name: Ingle, Suzanne M.
name: Crane, Heidi M.
name: Glass, Tracy R.
name: Yip, Benita
name: Lima, Viviane D.
name: Gill, M John
name: Hanhoff, Nikola
name: Ammassari, Adriana
name: Mugavero, Michael J.
name: Tate, Jan P.
name: Guest, Jodie
name: Turner, Nicholas L.
name: May, Margaret T.
name: Sterne, Jonathan A. C.
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Adherence to antiretroviral therapy (ART) is critical for successful treatment of Human Immunodeficiency Virus (HIV), but comparisons across settings are difficult because adherence is measured in different ways. We examined utility of different adherence measures for identification of patients at risk of viral failure (VF). Eight cohorts in the ART Cohort Collaboration contributed data from pharmacy refills or self-report questionnaires collected between 1996 and 2013 (N = 11689). For pharmacy data (N = 7156), we examined associations of percentage adherence during the 1st year of ART with VF (>500 copies/mL) at 1 year. For self-report data (N = 4533), we examined 28-day adherence with VF based on closest viral load measure within 6 months after questionnaire date. Since adherence differed markedly by measurement type, we defined different cut-off points for pharmacy (lower <45%, medium 45–99%, higher 100%) and self-report (lower ≤95%, medium 96–99%, higher 100%) data. Adjusted odds ratios (ORs) for VF in lower and medium, compared to higher adherence groups, were 23.04 (95% CI: 18.44–28.78) and 3.84 (3.36–4.39) for pharmacy data. For self-report data, they were 3.19 (2.31–4.40) and 1.08 (0.80–1.46). Both types of measure were strongly associated with VF. Although adherence measurements over longer time-frames are preferable for prediction, they are less useful for intervention.
Targeted alignment and end repair elimination increase alignment and methylation measure accuracy for reduced representation bisulfite sequencing data
Creators: name: Baheti, Saurabh
name: Kanwar, Rahul
name: Goelzenleuchter, Meike
name: Kocher, Jean-Pierre A.
name: Beutler, Andreas S.
name: Sun, Zhifu
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: TRACE-RRBS
subject: Reduced representation bisulfite sequencing
subject: RRBS
subject: DNA
subject: methylation
subject: RRBS alignment
subject: Methylation measure accuracy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background DNA methylation is an important epigenetic modification involved in many biological processes. Reduced representation bisulfite sequencing (RRBS) is a cost-effective method for studying DNA methylation at single base resolution. Although several tools are available for RRBS data processing and analysis, it is not clear which strategy performs the best and there has not been much attention to the contamination issue from artificial cytosines incorporated during the end repair step of library preparation. To address these issues, we describe a new method, Targeted Alignment and Artificial Cytosine Elimination for RRBS (TRACE-RRBS), which aligns bisulfite sequence reads to MSP1 digitally digested reference and specifically removes the end repair cytosines. We compared this approach on a simulated and a real dataset with 7 other RRBS analysis tools and Illumina 450 K microarray platform. Results TRACE-RRBS aligns sequence reads to a small fraction of the genome where RRBS protocol targets on and was demonstrated as the fastest, most sensitive and specific tool for the simulated dataset. For the real dataset, TRACE-RRBS took about the same time as RRBSMAP, a third to a sixth of time needed for BISMARK and NOVOALIGN. TRACE-RRBS aligned more reads uniquely than other tools and achieved the highest correlation with 450 k microarray data. The end repair artificial cytosine removal increased correlation between nearby CpGs and accuracy of methylation quantification. Conclusions TRACE-RRBS is fast and more accurate tool for RRBS data analysis. It is freely available for academic use at http://​bioinformaticsto​ols.​mayo.​edu/​.
White matter lesions, C-reactive protein and microglia: A putative relation
Creators: name: Juma, Wafa M
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Biology, Neuroscience.

description: White matter lesions (WML) are a clinically significant, common feature of the ageing brain associated with cognitive decline and depression. Recent research has been focused on identifying parameters which may have a correlation with WML. To this effect the acute phase protein, C-reactive protein (CRP) was shown to have an increased plasma level with progressive WML in human studies. However, due to the limitations of humam-based research the expression of CRP from brain tissue demonstrating progressive WML over a given period has not been reported. Our results have shown elevated mRNA and protein expression of CRP from rat brain tissue manifesting features of WML. Moreover, we have demonstrated that microglia, cultured from rat brain, are a source of mRNA and protein expression of CRP. We suggest that this key novel relation could be a target for future therapeutic interventions in diseases where WML and microglial activity are prominent features.
title: Pacientes en Hemodiálisis con trombosis múltiples del acceso vascular
Creators: name: Aleman Navarro, Carmen Maria
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Interventional vascular
subject: Vascular
subject: Fluoroscopy
subject: Angioplasty
subject: Stents
subject: Surgery
subject: Fistula
subject: Grafts

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Estudiar los factores que influyen en la trombosis del acceso vascular (nativo o injerto). Conocer cuáles son las alternativas terapéuticas de las que disponemos y sus indicaciones. Aproximación a futuros...
title: ENCEFALITIS LIMBICA: Infecciones, síndromes paraneoplásicos y enfermedades autoinmunes.
Creators: name: Plata Ariza, Diana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: MR
subject: Neuroradiology brain

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Clasificar las encefalitis límbicas en función de la etiología y fisiopatología. Describir los hallazgos de imagen en RM de los diferentes subtipos de encefalitis límbica. Realizar un diagnóstico diferencial con otras posibles causas de...