cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Safe and Effective Cynomolgus Monkey GLP—Tox Study with Repetitive Intrathecal Application of a TGFBR2 Targeting LNA-Gapmer Antisense Oligonucleotide as Treatment Candidate for Neurodegenerative Disorders
Creators: name: Peters, Sebastian Thomas
name: Wirkert, Eva
name: Kuespert, Sabrina
name: Heydn, Rosmarie
name: Johannesen, Siw Wollebæk
name: Friedrich, Anita
name: Mailänder, Susanne
name: Korte, Sven
name: Mecklenburg, Lars
name: Aigner, Ludwig
name: Bruun, Tim-Henrik
name: Bogdahn, Ulrich
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: AMYOTROPHIC-LATERAL-SCLEROSIS; BETA; INHIBITION; NUSINERSEN; RILUZOLE; INJURY; AGENT; TGF beta-signaling; neurogenesis; neurodegeneration; amyotrophic lateral sclerosis; GLP-ToxStudy; antisense oligonucleotide therapy; LNA
subject: 610 Medizin

description: The capability of the adult central nervous system to self-repair/regenerate was demonstrated repeatedly throughout the last decades but remains in debate. Reduced neurogenic niche activity paralleled by a profound neuronal loss represents fundamental hallmarks in the disease course of neurodegenerative disorders. We and others have demonstrated the endogenous TGF beta system to represent a potential pathogenic participant in disease progression, of amyotrophic lateral sclerosis (ALS) in particular, by generating and promoting a disequilibrium of neurodegenerative and neuroregenerative processes. The novel human/primate specific LNA Gapmer Antisense Oligonucleotide "NVP-13 ", targeting TGFBR2, effectively reduced its expression and lowered TGF beta signal transduction in vitro and in vivo, paralleled by boosting neurogenic niche activity in human neuronal progenitor cells and nonhuman primate central nervous system. Here, we investigated NVP-13 in vivo pharmacology, safety, and tolerability following repeated intrathecal injections in nonhuman primate cynomolgus monkeys for 13 weeks in a GLP-toxicology study approach. NVP-13 was administered intrathecally with 1, 2, or 4 mg NVP-13/animal within 3 months on days 1, 15, 29, 43, 57, 71, and 85 in the initial 13 weeks. We were able to demonstrate an excellent local and systemic tolerability, and no adverse events in physiological, hematological, clinical chemistry, and microscopic findings in female and male Cynomolgus Monkeys. Under the conditions of this study, the no observed adverse effect level (NOAEL) is at least 4 mg/animal NVP-13.
title: Virgilio deguisat o l'Eneido burlesco
Creators: name: VALES
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Source: Bibliothèque patrimoniale Villon (Rouen), m8308
Nectopsyche separata
Creators: name: Neto, Pedro Bonfá
name: Vilarino, Albane
name: Salles, Frederico F.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Leptoceridae
Nectopsyche
Nectopsyche separata

description: Nectopsyche separata (Banks 1920)
Distribution. Argentina, Brazil (Espírito Santo, Minas Gerais, Paraná, Rio de Janeiro, Santa Catarina, S„o Paulo), Paraguay.
Material examined. P15: 11–12.i.2016 (2♁♁); P16: 28.xii.2017 (1♁), 17–18.i.2018 (1♁), 18–19.xi.2017 (3♀♀); P18: 14–15.iv.2018 (1♁), 21.x–18.xi.2017 (1♀), 28.xii.2017 (1♀), 17–18.i.2018 (1♀), 20–21.iii.2018 (2♀♀); P20: 19.xi.2015 (2♁♁).
description: Published as part of Neto, Pedro Bonfá, Vilarino, Albane & Salles, Frederico F., 2023, Brevitentoria Weaver 1984 (Trichoptera: Integripalpia) of Espírito Santo State, Brazil: New records and new species, pp. 301-327 in Zootaxa 5336 (3) on page 317, DOI: 10.11646/zootaxa.5336.3.1, http://zenodo.org/record/8281432
Expression of Proton-Sensitive GPR31, GPR151, TASK1 and TASK3 in Common Skin Tumors
Creators: name: Förch, Antonia
name: Wallner, Susanne
name: Zeman, Florian
name: Ettl, Tobias
name: Brochhausen, Christoph
name: Schreml, Stephan
Publisher: name: Universität Regensburg
Year: 2021
Subjects: subject: PROTEIN-COUPLED RECEPTORS; LACTIC-ACID; POTASSIUM CHANNELS; CRYSTAL-STRUCTURE; CELL-MIGRATION; K+ CHANNEL; ACIDIFICATION; CANCER; GPCR31; 151; TASK1; 3; Task1; skin tumors
subject: 610 Medizin

description: TWIK-related acid-sensitive potassium channels TASK1 and TASK3, as well as the G-protein-coupled receptors GPR31 and GPR151, are proton-sensitive membrane proteins. They can be activated or inhibited by low extracellular pH (pHe), which is a hallmark of the tumor microenvironment in solid tumors. However, the role of these channels in the development of skin tumors is still unclear. In this study, we investigated the expression profiles of TASK1, TASK3, GPR31 and GPR151 in squamous cell carcinomas (SCCs), basal cell carcinomas (BCCs), nevus cell nevi (NCN), and malignant melanomas (MMs). We performed immunohistochemistry using paraffin-embedded tissue samples from patients and found that most skin tumors express TASK1/3 and GPR31/151. The results show that BCCs are often negative for GPR31/151 as well as for TASK1/3, while nearly all SCCs express these markers. MMs and NCN show similar expression patterns. However, some tumors show a decreasing TASK1/3 expression in deeper dermal tumor tissue, while GPCRs were expressed more evenly. The lower frequency of GPR31/151 and TSAK1/3 expression in BCCs when compared to SCCs is a novel histological feature distinguishing these two entities. Moreover, BCCs also show lower expression of GPR31/151 and TASK1/3 as compared to NCN and MMs.
Peromyscus beatae Thomas 1903
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus beatae

description: Peromyscus beatae Thomas 1903
Peromyscus beatae Thomas 1903, Ann. Mag. Nat. Hist., ser. 7, 11: 485.
Type Locality: México, Veracruz, Mt Orizaba.
Vernacular Names: Orizaba Deermouse.
Synonyms: Peromyscus sacarensis Dickey 1928.
Distribution: C Veracruz and C Guerrero to Oaxaca and Chiapas, México, southwards through highlands of Guatemala, El Salvador, and Honduras.
Discussion: P. boylii species group. Formerly arranged as a synonym of P. boylii levipes (Hooper, 1968; Osgood, 1909) or P. levipes (Carleton, 1989). Specific status, including sacarensis as junior synonym and recognized subspecies, reasserted based on karyotypic, morphologic, and genetic evidence (Bradley and Schmidly, 1987; Bradley et al., 1989, 2000; Houseal et al. 1987; Schmidly et al., 1988). Sister taxon of P. levipes; taxonomic level of differentiation of populations west (beatae) and east (sacarensis) of the Isthmus of Tehuantepec requires additional study (see Bradley et al., 2000).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1063, DOI: 10.5281/zenodo.7316535
Cossulus nikiforoviorum Yakovlev 2006
Creators: name: Yakovlev, Roman V.
name: Witt, Thomas J.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Cossidae
Cossulus
Cossulus nikiforoviorum

description: Cossulus nikiforoviorum Yakovlev, 2006
(Figs 50, 90)
Cossulus nikiforoviorum Yakovlev, 2006: 6 ̄7.
Type locality: Uzbekistan, Ghissar Range, 60 km E. Shakhrisabz. Type material (holotype) in MWM, examined.
Distribution: Uzbekistan, Ghissar Mts.
Habitat and biology. Flight period: July. Altitude: 2500 m.
description: Published as part of Yakovlev, Roman V. & Witt, Thomas J., 2017, World catalogue of the genus Cossulus Staudinger, 1887 (Lepidoptera, Cossidae) with description of Cossulus irtlachi sp. nov. from Kyrgyzstan in Zootaxa 4311 (1), DOI: 10.11646/zootaxa.4311.1.4, http://zenodo.org/record/847333
title: Eau_2018-2019
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: Eau
subject: eau chaude
subject: eau froide
subject: Litre

description: - Eau froide (Litre)
- Eau chaude (Litre)
- Date
- num capteur
A Polymorphism of Bactericidal/Permeability-Increasing Protein Affects Its Neutralization Efficiency towards Lipopolysaccharide
Creators: name: Ederer, Katharina U.
name: Holzinger, Jonas M.
name: Maier, Katharina T.
name: Zeller, Lisa
name: Werner, Maren
name: Toelge, Martina
name: Gessner, André
name: Bülow, Sigrid
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: GRAM-NEGATIVE BACTERIA; N-TERMINAL FRAGMENT; VERSUS-HOST-DISEASE; CRYSTAL-STRUCTURE; BINDING PROTEIN; GENE VARIANTS; BPI; SEPSIS; RELEASE; DEFICIENT; bactericidal; permeability-increasing; lipopolysaccharide; sepsis; single nucleotide polymorphism
subject: 610 Medizin

description: Gram-negative sepsis driven by lipopolysaccharide (LPS) has detrimental outcomes, especially in neonates. The neutrophil-derived bactericidal/permeability-increasing protein (BPI) potently neutralizes LPS. Interestingly, polymorphism of the BPI gene at position 645 (rs4358188) corresponds to a favorable survival rate of these patients in the presence of at least one allele 645 A as opposed to 645 G. When we exploited the existing X-ray crystal structure, the corresponding amino acid at position 216 was revealed as surface exposed and proximal to the lipid-binding pocket in the N-terminal domain of BPI. Our further analysis predicted a shift in surface electrostatics by a positively charged lysine (BPI216K) exchanging a negatively charged glutamic acid (BPI216E). To investigate differences in interaction with LPS, we expressed both BPI variants recombinantly. The amino acid exchange neither affected affinity towards LPS nor altered bactericidal activity. However, when stimulating human peripheral blood mononuclear cells, BPI216K exhibited a superior LPS-neutralizing capacity (IC50 12.0 +/- 2.5 pM) as compared to BPI216E (IC50 152.9 +/- 113.4 pM, p = 0.0081) in respect to IL-6 secretion. In conclusion, we provide a functional correlate to a favorable outcome of sepsis in the presence of BPI216K.
Nectopsyche muhni
Creators: name: Neto, Pedro Bonfá
name: Vilarino, Albane
name: Salles, Frederico F.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Leptoceridae
Nectopsyche
Nectopsyche muhni

description: Nectopsyche muhni (Navás 1916)
Distribution. Argentina, Bolivia, Brazil (Espírito Santo, Maranh„o, Minas Gerais, Piauí, Rio de Janeiro, Roraima, S„o Paulo), Ecuador, Guyana, Paraguay, Peru, Suriname, Venezuela.
Material examined. P01: 25–26.vii.2012 (3♁♁); P03: 26–27.vi.2012 (1♁); P04: 25–26.vii.2012 (1♁), 18– 19.iv.2012 (1♀, 1♁); P13: 21–22.x.2017 (1♁), 18–19.xi.2017 (1♁); P14: 11.i.2016 (1♁); P16: 18–19.xi.2017 (1♁), 17–18.i.2018 (2♁♁), 20–21.iii.2018 (1♁); P20: 19.xi.2015 (13♁♁).
description: Published as part of Neto, Pedro Bonfá, Vilarino, Albane & Salles, Frederico F., 2023, Brevitentoria Weaver 1984 (Trichoptera: Integripalpia) of Espírito Santo State, Brazil: New records and new species, pp. 301-327 in Zootaxa 5336 (3) on page 317, DOI: 10.11646/zootaxa.5336.3.1, http://zenodo.org/record/8281432
Is Vesicostomy Still a Contemporary Method of Managing Posterior Urethral Valves?
Creators: name: Hofmann, Aybike
name: Haider, Maximilian
name: Cox, Alexander
name: Vauth, Franziska
name: Rösch, Wolfgang H.
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: URINARY-DIVERSION; ABLATION; CHILDREN; INFANTS; TRACT; BOYS; posterior urethral valves; vesicostomy; congenital urinary tract obstruction; kidney function; vesicoureteral reflux; long-term outcome
subject: 610 Medizin

description: In boys with posterior urethral valves (PUVs) the main treatment aim is to preserve long-term bladder and renal function. To determine the effectiveness of secondary vesicostomy in boys with PUVs, the medical records of 21 patients with PUV (2010-2019), divided into two groups (group I: valve ablation; group II: secondary vesicostomy), were reviewed regarding the course of serum creatinine, renal ultrasound, voiding cystourethrogram, urodynamics, postoperative complications, need of further surgery, and long-term solution. The median age of all patients at first follow-up was 11 (9-13) months and at last follow-up 64.5 (39.5-102.5) months. Despite a significant difference of the SWDR score (shape, wall, reflux, and diverticula) (p = 0.014), both groups showed no significant differences preoperatively. Postoperatively, serum creatinine (p = 0.024), grade of vesicoureteral reflux (p = 0.003), side of upper tract dilatation (p = 0.006), side of megaureter (p = 0.004), and SWDR score (p = 0.002) were significantly decreased in group II. Postoperative urodynamic measurements showed comparable results in both groups. Stoma complications were found in three (20%) patients (group II). Eight (53.3%) patients already received a closure of the vesicostomy. Seven out of eight (87.5%) patients were able to micturate spontaneously. Vesicostomy remains a reliable treatment option for boys with PUV to improve bladder function and avoid further damage to the urinary tract.
Peromyscus boylii Baird 1855
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus boylii

description: Peromyscus boylii Baird 1855
Peromyscus boylii Baird 1855, Proc. Acad. Nat. Sci. Philadelphia, 7: 335.
Type Locality: USA, California, Eldorado Co., Middle Fork of American River, near Auburn.
Vernacular Names: Brush Deermouse.
Synonyms: Peromyscus gaurus Elliot 1903; Peromyscus glasselli Burt 1932; Peromyscus major (Rhoads 1893); Peromyscus metallicola Elliot 1904; Peromyscus parasiticus Elliot 1904; Peromyscus pinalis (Miller 1893); Peromyscus robustus (J. A. Allen 1893); Peromyscus rowleyi (J. A. Allen 1893); Peromyscus utahensis Durrant 1946.
Distribution: Much of SW USA, from N California to westernmost Oklahoma, south to N Baja California Norte and Trans-Pecos Texas (see Bradley et al., 1999 a), along the Sierra Madre Occidental and W Central Plateau to Queretaro and W Hidalgo, México.
Conservation: IUCN – Lower Risk (lc).
Discussion: P. boylii species group. Many taxa previously consigned as subspecies or full synonyms by Osgood (1909) or Hall (1981) have been elevated to species: namely P. attwateri (see Schmidly, 1973), P. aztecus (see Alvarez, 1961; Carleton, 1979; Hooper, 1968), P. baetae (see Bradley and Schmidly, 1987; Schmidly et al., 1988), P. levipes (see Schmidly et al., 1988), P. madrensis (see Carleton, 1977; Carleton et al., 1982), P. simulus (see Carleton, 1977), P. sagax (see Bradley et al., 1996 a), and P. spicilegus (see Carleton, 1977). Others have been realigned with other species— cordillerae and evides under P. aztecus (Carleton, 1979); ambiguus under P. levipes (Castro-Campillo et al, 1999; Schmidly et al., 1988); sacarensis under P. baetae (Bradley et al., 2000); and penicillatus under P. nasutus (Diersing, 1976).
These changes in status and synonymy of taxa once associated under one species sensu Osgood (1909) involve the systematics of at least three species groups by current understanding. Chromosomal and molecular information suggests that yet other forms in W México await differential characterization as species (see overview by Tiemann-Boege et al., 2000). Karyotypic variation of P. boylii and its kin investigated by Houseal et al. (1987), Lee et al. (1972), and Schmidly and Schroeter (1974); biochemical and molecular variation by Avise et al. (1974), Kilpatrick and Zimmerman (1975), Rennert and Kilpatrick (1986, 1987), Sullivan et al. (1991), Tiemann-Boege et al. (2000); morphological variation by Bradley and Schmidly (1987), Carleton (1977, 1979), and Schmidly et al. (1988).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1064, DOI: 10.5281/zenodo.7316535
Cossulus nycteris
Creators: name: Yakovlev, Roman V.
name: Witt, Thomas J.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Cossidae
Cossulus
Cossulus nycteris

description: Cossulus nycteris (John, 1923)
Hypopta nycteris John, 1923: 91.
Type locality: Namangan, at Tosté on the river Padsha-ata. Type material (holotype) in ZISP. Possibly lost. Distribution: Uzbekistan.
description: Published as part of Yakovlev, Roman V. & Witt, Thomas J., 2017, World catalogue of the genus Cossulus Staudinger, 1887 (Lepidoptera, Cossidae) with description of Cossulus irtlachi sp. nov. from Kyrgyzstan in Zootaxa 4311 (1), DOI: 10.11646/zootaxa.4311.1.4, http://zenodo.org/record/847333
Neoathripsodes undetermined
Creators: name: Neto, Pedro Bonfá
name: Vilarino, Albane
name: Salles, Frederico F.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Leptoceridae
Neoathripsodes
Neoathripsodes undetermined

description: Neoathripsodes sp.
Distribution. Brazil (Espírito Santo).
Remarks. Species under description (Dias & Calor 2015) not yet published as a valid taxon. All species of this genus have a distribution restricted to the Atlantic Forest and can be considered endemic to the Biome.
Material examined. P18: 20.iii–14.iv.2018 (1♁), 30.i–21.x.2017 (1♁), 21.x–18.xi.2017 (1♁).
description: Published as part of Neto, Pedro Bonfá, Vilarino, Albane & Salles, Frederico F., 2023, Brevitentoria Weaver 1984 (Trichoptera: Integripalpia) of Espírito Santo State, Brazil: New records and new species, pp. 301-327 in Zootaxa 5336 (3) on page 317, DOI: 10.11646/zootaxa.5336.3.1, http://zenodo.org/record/8281432
Economic and social framework in Herculaneum
Creators: name: Lepore, Ettore
name: Marichal, Robert
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 7
description: Annotations on Ettore Lepore, Sul carattere economico-sociale di Ercolano, "PP" 10 (1955),423-439; numbers of pages and thematic heading ('Herculaneum. Econom-Social') on the upper right corner of each page. - Smaller sheets of papers containing bibliographical references and a few annotations on Herculaneum graffiti.
description: Source: 4MAR_8_2_5-9
description: created: n.d.
Peromyscus bullatus Osgood 1904
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus bullatus

description: Peromyscus bullatus Osgood 1904
Peromyscus bullatus Osgood 1904, Proc. Biol. Soc. Wash., 17: 63.
Type Locality: México, Veracruz, Perote.
Vernacular Names: Perote Deermouse.
Distribution: Known from only two localities in Veracruz, EC México.
Conservation: IUCN – Endangered.
Discussion: P. truei species group. Retained as a species since its discovery (Carleton, 1989; Hoffmeister, 1951; Osgood, 1909), although Hooper (1968) suspected that it would prove to be a subspecies of P. truei, a possibility that has yet to be addressed.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1064, DOI: 10.5281/zenodo.7316535
PROTOCOL OF PRELIMINARY ACTIONS FOR AIRCRAFT PROTECTION - Deliverable D6.2
Creators: name: Fiser Jaromir
Publisher: name: Zenodo
Year: 2023
Subjects: PROCRAFT
Aircraft
Cultural Heritage
WWII
Aluminium Alloy
Duralumin
Preventive conservation
museum
Aviation Archaeology

description: This deliverable reports on the work carried out in Task 6.2 of WP6 (actions for preventive protection - subtask to Task 6.2), which concerns preliminary actions for preventive protection, namely measurement devices and data loggers installation, in selected representative sites (museum building, storage hangar open or closed, possibly roofed).
Cossulus putridus
Creators: name: Yakovlev, Roman V.
name: Witt, Thomas J.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Cossidae
Cossulus
Cossulus putridus

description: Cossulus putridus (Christoph, 1887)
(Figs 51 ̄52, 91)
Holcocerus putridus Christoph, 1887: 57 ̄58.
Type locality: Aschabad [Turkmenistan, Ashkhabad].
Type material (cotypes) in ZISP, examined.
Distribution: Turkmenistan, Iran, Afghanistan (Yakovlev, 2006). Habitat and biology. Flight period: August. Altitude: 700̄ 2000 m.
description: Published as part of Yakovlev, Roman V. & Witt, Thomas J., 2017, World catalogue of the genus Cossulus Staudinger, 1887 (Lepidoptera, Cossidae) with description of Cossulus irtlachi sp. nov. from Kyrgyzstan in Zootaxa 4311 (1), DOI: 10.11646/zootaxa.4311.1.4, http://zenodo.org/record/847333
An Evaluation of Different 3D Cultivation Models on Expression Profiles of Human Periodontal Ligament Fibroblasts with Compressive Strain
Creators: name: Schröder, Agnes
name: Schöniger, Ricarda
name: Oeldemann, Juliane
name: Spanier, Gerrit
name: Proff, Peter
name: Jantsch, Jonathan
name: Kirschneck, Christian
name: Ullrich, Niklas
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: ORTHODONTIC TOOTH MOVEMENT; FACTOR-KAPPA-B; CELL; OSTEOCLASTOGENESIS; DISEASE; BIOMATERIALS; ACTIVATION; MICROARRAY; MIGRATION; TISSUE; 3D cell culture; fibroblasts; PDLF; periodontal ligament; orthodontics; pressure; tooth movement
subject: 610 Medizin

description: The effects of compressive strain during orthodontic treatment on gene expression profiles of periodontal ligament fibroblasts (PDLFs) have mostly been studied in 2D cell culture. However, cells behave differently in many aspects in 3D culture. Therefore, the effect of pressure application on PDLFs in different 3D structures was investigated. PDLFs were either conventionally seeded or embedded into different 3D structures (spheroids, Mebiol(R) gel, 3D scaffolds) and exposed to compressive force or incubated without pressure. For one 3D scaffold (POR), we also tested the effect of different compressive forces and application times. Expression of an angiogenic gene (VEGF), a gene involved in extracellular matrix synthesis (COL1A2), inflammatory genes (IL6, PTGS2), and genes involved in bone remodelling (OPG, RANKL) were investigated by RT-qPCR. Depending on the used 3D cell culture model, we detected different effects of compressive strain on expression profiles of PDLFs. COL1A2 was downregulated in all investigated 3D culture models. Angiogenetic and proinflammatory genes were regulated differentially between models. In 3D scaffolds, regulation of bone-remodelling genes upon compressive force was contrary to that observed in 3D gels. 3D cell culture models provide better approximations to in vivo physiology, compared with conventional 2D models. However, it is crucial which 3D structures are used, as these showed diverse effects on the expression profiles of PDLFs during mechanical strain.
Peromyscus californicus Gambel 1848
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus californicus

description: Peromyscus californicus Gambel 1848
Peromyscus californicus Gambel 1848, Proc. Acad. Nat. Sci. Philadelphia, 4: 78.
Type Locality: USA, California, Monterey Co., Monterey.
Vernacular Names: California Deermouse.
Synonyms: Peromyscus benitoensis Grinnell and Orr 1934; Peromyscus insignis Rhoads 1895; Peromyscus mariposae Grinnell and Orr 1934; Peromyscus parasiticus (Baird 1857).
Distribution: C and S California, USA, excluding San Joaquin Valley, to NW Baja California Norte, México.
Conservation: IUCN – Lower Risk (lc).
Discussion: P. californicus species group. Electrophoretic and morphometric variation investigated by Smith (1979), who retained only a northern (californicus) and southern (insignis) subspecies. See Merritt (1978, Mammalian Species, 85).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1064, DOI: 10.5281/zenodo.7316535
Cossulus sergechurkini Yakovlev 2008
Creators: name: Yakovlev, Roman V.
name: Witt, Thomas J.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Cossidae
Cossulus
Cossulus sergechurkini

description: Cossulus sergechurkini Yakovlev, 2008
(Figs 53, 92)
Cossulus sergechurkini Yakovlev, 2008: 45.
Type locality: [Kyrgyzstan], Fergana Valley, 27 km S Osh. Type material (holotype) in MWM, examined.
Distribution: Kyrgyzstan, Fergana Valley.
Habitat and biology. Flight period: July. Altitude: 1200 m.
description: Published as part of Yakovlev, Roman V. & Witt, Thomas J., 2017, World catalogue of the genus Cossulus Staudinger, 1887 (Lepidoptera, Cossidae) with description of Cossulus irtlachi sp. nov. from Kyrgyzstan in Zootaxa 4311 (1), DOI: 10.11646/zootaxa.4311.1.4, http://zenodo.org/record/847333
Peromyscus caniceps Burt 1932
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus caniceps

description: Peromyscus caniceps Burt 1932
Peromyscus caniceps Burt 1932, Trans. San Diego Soc. Nat. Hist., 7: 174.
Type Locality: México, Baja California Sur, Monserrat Isl; 25°38'N, 111°02'W.
Vernacular Names: Monserrat Island Deermouse.
Distribution: Known only from Monserrat Isl.
Conservation: IUCN – Vulnerable.
Discussion: P. eremicus species group. Although membership in Haplomylomys is generally recognized (Avise et al., 1971; Burt, 1932; Hooper, 1968), nearest kin and specific stature unresolved. Affinity to P. eva highlighted by Lawlor (1971 b), who suggested its possible ranking as a subspecies thereof, but later (1983) maintained it as an insular species. Strongly and about equally differentiated from examples of P. eva, P. eremicus, and P. fraterculus based on allozymic comparisons by Avise et al. (1974). Listed, without explanation, in the crinitus species group by Hall (1981). Reassigned as a subspecies of P. fraterculus based on mitochondrial DNA similarity by Hafner et al. (2001). Nevertheless, the bacular contrasts to P. eremicus and P. fraterculus, as recorded by Lawlor (1971 b), are impressive and recommend additional morphological and molecular comparisons that include Burt’s (1932) original type series, reference samples of P. eva and P. fraterculus, and the recent vouchers utilized by Hafner et al. (2001). See Alvarez-Castañeda et al. (1998, Mammalian Species, 602).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1065, DOI: 10.5281/zenodo.7316535
Personalization of Repetitive Transcranial Magnetic Stimulation for the Treatment of Chronic Subjective Tinnitus
Creators: name: Schoisswohl, Stefan
name: Langguth, Berthold
name: Hebel, Tobias
name: Vielsmeier, Veronika
name: Abdelnaim, Mohamed A.
name: Schecklmann, Martin
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: MOTOR CORTEX EXCITABILITY; HANDICAP INVENTORY; RTMS; INDEX; TMS; METAANALYSIS; DEPRESSION; SESSIONS; PATIENT; repetitive transcranial magnetic stimulation; tinnitus; neuronavigation; rTMS personalization; neuromodulation
subject: 610 Medizin

description: Background: Personalization of repetitive transcranial magnetic stimulation (rTMS) for tinnitus might be capable to overcome the heterogeneity of treatment responses. The assessment of loudness changes after short rTMS protocols in test sessions has been proposed as a strategy to identify the best protocol for the daily treatment application. However, the therapeutic advantages of this approach are currently not clear. The present study was designed to further investigate the feasibility and clinical efficacy of personalized rTMS as compared to a standardized rTMS protocol used for tinnitus. Methods: RTMS personalization was conducted via test sessions and reliable, sham-superior responses respectively short-term reductions in tinnitus loudness following active rTMS protocols (1, 10, 20 Hz, each 200 pulses) applied over the left and right temporal cortex. Twenty pulses at a frequency of 0.1 Hz served as a control condition (sham). In case of a response, patients were randomly allocated to ten treatment sessions of either personalized rTMS (2000 pulses with the site and frequency producing the most pronounced loudness reduction during test sessions) or standard rTMS (1 Hz, 2000 pulses left temporal cortex). Those participants who did not show a response during the test sessions received the standard protocol as well. Results: The study was terminated prematurely after 22 patients (instead of 50 planned) as the number of test session responders was much lower than expected (27% instead of 50%). Statistical evaluation of changes in metric tinnitus variables and treatment responses indicated only numerical, but not statistical superiority for personalized rTMS compared to standard treatment. Conclusions: The current stage of investigation does not allow for a clear conclusion about the therapeutic advantages of personalized rTMS for tinnitus based on test session responses. The feasibility of this approach is primarily limited by the low test session response rate.
Notalina (Neonotalina) cipo Holzenthal 1986
Creators: name: Neto, Pedro Bonfá
name: Vilarino, Albane
name: Salles, Frederico F.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Leptoceridae
Notalina
Notalina cipo

description: Notalina (Neonotalina) cipo Holzenthal 1986
Distribution. Brazil (Bahia, Espírito Santo, Minas Gerais, S„o Paulo).
Material examined. P13: 28–29.iv.2017 (3♁♁), 27–28.v.2017 (1♁), 27.v–21.vi.2017 (1♁), 21–22.vi.2017 (1♁), 26.vii–23.viii.2017 (1♁), 23–24.viii.2017 (1♁), 24.viii–30.ix.2017 (1♁), 21–22.x.2017 (3♁♁), 28.xii.2017 (6♁♁), 19.xii.2017 – 17.i.2018 (1♁), 17–18.i.2018 (1♁), 17.i–20.ii.2018 (3♁♁), 20–21.ii.2018 (1♁), 20.ii– 20.iii.2018 (1♁), 20–21.iii.2018 (3♁♁), 20.iii–14.iv.2018 (2♁♁), 14–15.iv.2018 (1♁); P16: 18–19.xi.2017 (2♁♁), 28.xii.2017 (1♁), 17–18.i.2018 (3♁♁), 20–21.iii.2018 (3♁♁), 14–15.iv.2018 (1♁); P18: 23–24.viii.2017 (1♁), 21.x–18.xi.2017 (1♁), 18–19.xi.2017 (1♁), 18.xi–19.xii.2017 (1♁), 17–18.i.2018 (2♁♁), 17.i–20.ii.2018 (2♁♁), 20–21.ii.2018 (1♁), 20–21.iii.2018 (1♁).
description: Published as part of Neto, Pedro Bonfá, Vilarino, Albane & Salles, Frederico F., 2023, Brevitentoria Weaver 1984 (Trichoptera: Integripalpia) of Espírito Santo State, Brazil: New records and new species, pp. 301-327 in Zootaxa 5336 (3) on page 317, DOI: 10.11646/zootaxa.5336.3.1, http://zenodo.org/record/8281432
Emerging Insights on the Diverse Roles of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Chronic Liver Diseases: Cholesterol Metabolism and Beyond
Creators: name: Grewal, Thomas
name: Buechler, Christa
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: PCSK9; LDL-receptor; hepatitis C; NAFLD; alcoholic liver disease; visceral obesity
subject: 610 Medizin

description: Chronic liver diseases are commonly associated with dysregulated cholesterol metabolism. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease of the proprotein convertase family that is mainly synthetized and secreted by the liver, and represents one of the key regulators of circulating low-density lipoprotein (LDL) cholesterol levels. Its ability to bind and induce LDL-receptor degradation, in particular in the liver, increases circulating LDL-cholesterol levels in the blood. Hence, inhibition of PCSK9 has become a very potent tool for the treatment of hypercholesterolemia. Besides PCSK9 limiting entry of LDL-derived cholesterol, affecting multiple cholesterol-related functions in cells, more recent studies have associated PCSK9 with various other cellular processes, including inflammation, fatty acid metabolism, cancerogenesis and visceral adiposity. It is increasingly becoming evident that additional roles for PCSK9 beyond cholesterol homeostasis are crucial for liver physiology in health and disease, often contributing to pathophysiology. This review will summarize studies analyzing circulating and hepatic PCSK9 levels in patients with chronic liver diseases. The factors affecting PCSK9 levels in the circulation and in hepatocytes, clinically relevant studies and the pathophysiological role of PCSK9 in chronic liver injury are discussed.
Peromyscus crinitus Merriam 1891
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus crinitus

description: Peromyscus crinitus Merriam 1891
Peromyscus crinitus Merriam 1891, N. Amer. Fauna, 5: 53.
Type Locality: USA, Idaho, Jerome Co., Shoshone Falls, north side of Snake River.
Vernacular Names: Canyon Deermouse.
Synonyms: Peromyscus auripectus (J. A. Allen 1893); Peromyscus delgadilli Benson 1940; Peromyscus disparilis Goldman 1932; Peromyscus doutii Goin 1944; Peromyscus pallidissimus Huey 1931; Peromyscus pergracilis Goldman 1939; Peromyscus peridoneus Goldman 1937; Peromyscus petraius Elliot 1904; Peromyscus rupicolus Benson 1940; Peromyscus scitulus Bangs 1899; Peromyscus scopulorum Benson 1940; Peromyscus stephensi Mearns 1897.
Distribution: E Oregon and SW Idaho, south through Nevada and parts of Utah and W Colorado, USA, to EC Baja California Norte and NW Sonora, México.
Conservation: IUCN – Lower Risk (lc).
Discussion: P. crinitus species group. Revised by Osgood (1909); subspecific taxonomy updated by Hall and Hoffmeister (1942). Initially placed in subgenus Haplomylomys (Osgood, 1909); later transferred to subgenus Peromyscus (Hooper and Musser, 1964 b). Karyotype viewed as primitive for the genus (Greenbaum and Baker, 1978; Stangl and Baker, 1984 b). Population on Isla San Luís Gonzaga (pallidissimus), N Sea of Cortez, genetically similar to mainland P. crinitus and retained as subspecies (Hafner et al., 2001). A composite of at least two species, the status of long-tailed forms (e.g., disparilis and delgadilli) in particular meriting reassessment. See Johnson and Armstrong (1987, Mammalian Species, 287).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1065, DOI: 10.5281/zenodo.7316535
Antibodies against viral nucleo-, phospho-, and X protein contribute to serological diagnosis of fatal Borna disease virus 1 infections
Creators: name: Neumann, Bernhard
name: Angstwurm, Klemens
name: Linker, Ralf A.
name: Knoll, Gertrud
name: Eidenschink, Lisa
name: Rubbenstroth, Dennis
name: Schlottau, Kore
name: Beer, Martin
name: Schreiner, Patrick
name: Soutschek, Erwin
name: Böhmer, Merle M.
name: Lampl, Benedikt M.J.
name: Pregler, Matthias
name: Scheiter, Alexander
name: Evert, Katja
name: Zoubaa, Saida
name: Riemenschneider, Markus J.
name: Asbach, Benedikt
name: Gessner, André
name: Niller, Hans Helmut
name: Schmidt, Barbara
name: Bauswein, Markus
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: ;
subject: 610 Medizin

description: Borna disease virus 1 (BoDV-1) causes rare but often fatal encephalitis in humans. Late diagnosis prohibits an experimental therapeutic approach. Here, we report a recent case of fatal BoDV-1 infection diagnosed on day 12 after hospitalization by detection of BoDV-1 RNA in the cerebrospinal fluid. In a retrospective analysis, we detect BoDV-1 RNA 1 day after hospital admission when the cell count in the cerebrospinal fluid is still normal. We develop a new ELISA using recombinant BoDV-1 nucleoprotein, phosphoprotein, and accessory protein X to detect seroconversion on day 12. Antibody responses are also shown in seven previously confirmed cases. The individual BoDV-1 antibody profiles show variability, but the usage of three different BoDV-1 antigens results in a more sensitive diagnostic tool. Our findings demonstrate that early detection of BoDV-1 RNA in cerebrospinal fluid and the presence of antibodies against at least two different viral antigens contribute to BoDV-1 diagnosis. Physicians in endemic regions should consider BoDV-1 infection in cases of unclear encephalopathy and initiate appropriate diagnostics at an early stage.
Notalina (Neonotalina) morsei Holzenthal 1986
Creators: name: Neto, Pedro Bonfá
name: Vilarino, Albane
name: Salles, Frederico F.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Leptoceridae
Notalina
Notalina morsei

description: Notalina (Neonotalina) morsei Holzenthal 1986
Distribution. Brazil (Espírito Santo, Minas Gerais, S„o Paulo, Rio de Janeiro).
Material examined. P21: 17–18.ii.2016 (1♁), 14–15.ii.2016 (1♀, 5♁♁).
description: Published as part of Neto, Pedro Bonfá, Vilarino, Albane & Salles, Frederico F., 2023, Brevitentoria Weaver 1984 (Trichoptera: Integripalpia) of Espírito Santo State, Brazil: New records and new species, pp. 301-327 in Zootaxa 5336 (3) on page 318, DOI: 10.11646/zootaxa.5336.3.1, http://zenodo.org/record/8281432
Cossulus sheljuzhkoi
Creators: name: Yakovlev, Roman V.
name: Witt, Thomas J.
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Cossidae
Cossulus
Cossulus sheljuzhkoi

description: Cossulus sheljuzhkoi (Zukowsky, 1936)
(Figs 54 ̄56, 93)
Hypopta sheljuzhkoi Zukowsky, 1936: 536.
Type locality: Thianshan occ., Bolshoj Tsimgan [Uzbekistan, Chatkal Mts. Range, Bol’shoi Chimgan]. Type material (syntypes) in MHUB, examined.
Distribution: S. Kazakhstan, Kyrgyzstan, Uzbekistan, Tajikistan (Yakovlev, 2006). Habitat and biology. Flight period: MaȳJuly. Altitude: 600̄ 2000 m.
description: Published as part of Yakovlev, Roman V. & Witt, Thomas J., 2017, World catalogue of the genus Cossulus Staudinger, 1887 (Lepidoptera, Cossidae) with description of Cossulus irtlachi sp. nov. from Kyrgyzstan in Zootaxa 4311 (1), DOI: 10.11646/zootaxa.4311.1.4, http://zenodo.org/record/847333
Peromyscus dickeyi Burt 1932
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus dickeyi

description: Peromyscus dickeyi Burt 1932
Peromyscus dickeyi Burt 1932, Trans. San Diego Soc. Nat. Hist., 7: 176.
Type Locality: México, Baja California Sur, Tortuga Isl; 27°21'N, 111°54'W.
Vernacular Names: Dickey's Deermouse.
Distribution: Known only from Tortuga Isl.
Conservation: IUCN – Endangered.
Discussion: P. eremicus species group. Genically similar to P. eremicus and P. merriami (Avise et al., 1974) and presumably originated from an eremicus like progenitor (Lawlor, 1983), but gene sequence data decisively portray mice on Tortuga Isl as derivatives of P. merriami (Hafner et al., 2001). The last authors have recommended the recognition of dickeyi as a subspecies of P. merriami. Cranium and fur traits of dickeyi do closely resemble those of P. merriami but the bullae appear smaller and the tail relatively shorter, diagnostic features noted by Burt (1932). A sounder footing for its synonymy and possible subspecific retention should involve broader morphological and molecular surveys within the range of P. merriami, together with the original type series of the island form. See Cortés-Calva and Alvarez-Castañeda (2001, Mammalian Species, 659).
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1065, DOI: 10.5281/zenodo.7316535
Aplysina lingua Pinheiro, Hajdu & Custódio, 2007, sp.n.
Creators: name: Pinheiro, Ulisses Dos S.
name: Hajdu, Eduardo
name: Custódio, Márcio R.
Publisher: name: Zenodo
Year: 2007
Subjects: Biodiversity
Taxonomy
Animalia
Porifera
Demospongiae
Verongida
Aplysinidae
Aplysina
Aplysina lingua

description: Aplysina lingua sp.n. (Figs. 16 C, 17B, 19, Tab. IX)
Holotype: MNRJ 5476, west coral head (Parque Nacional Marinho dos Abrolhos, BA, 17º57'703'' S - 36º14'795'' W), 18 m depth, E. Esteves and G. Muricy coll., 03/III/2002.
Paratype: MNRJ 5469, Parcel Paredes, south side, (Parque Nacional Marinho dos Abrolhos, BA, 17º53'499'' S - 38º58'034'' W), 10 m depth, U.S. Pinheiro and G. Muricy coll., 05/III/2002.
Diagnosis: Elongate lamellar form, similar to a tongue, Light yellow colour in vivo.
Description of the species
The specimen has an erect, tongue form (long, flattened, lamelar) with 18 cm length by 4 cm width and 2 cm thickness expanding toward the apex (Fig. 17 B, 19A). The small oscula (1 mm) are spread over the entire surface, which is very finely conulose. The colour is a mixture of light yellowish-brown, light pinkish-brown and light-yellow in vivo, which turns into dark brownish-purple after preservation in ethanol. Consistency is flexible.
Skeleton: Choanosome with a delicate and irregular network of spongin fibers (Fig. 19B). Bark with amber or reddish colour, thickness of 37–192 Μm (average 117 Μm) and thick pith that can be black or amber with thickness varying between 10 and 35 Μm (average 31 Μm; Fig. 19C).
Distribution: Provisionally known only from the type locality off the State of Bahia (Brazil; Fig. 16 C).
Ecology: The specimens were collected in a maximum of 18 m depth in shaded areas of coral heads.
Etymology: The name of the species is a noum in apposition and relates to its morphology tongue-like (tongue = lingua in Latin).
Remarks: A. lingua sp.n. approaches more closely the morphospace of A. fulva, known for its plasticity and undelimited diagnosis. Nevertheless, the hundreds to thousands of specimens of A. fulva observed at many localities along the Brazilian Coast only very seldom possessed a comparable mixture of colours when alive, and none of them were observed to comprise a single branch with a flattened, elongate, lamelar form.
TABLE IX: Spongin fibres’ measurement data for Aplysina lingua sp.n. (in micrometers; S.D. = Standard Deviation and N=30).
Specimens Locality* Fibers Piths
Thinnest Mean Thickest S.D. Thinnest Mean Thickest S.D.
Holotype Abrolhos, BA 60.0 147.7 192.5 35.6 10.0 20.5 35.0 6.1
MNRJ 5476
Paratype Abrolhos, BA 37.5 88.3 175.0 25.1 10.0 16.4 27.5 4.8
MNRJ 5469
*BA, Bahia State.
description: Published as part of Pinheiro, Ulisses Dos S., Hajdu, Eduardo & Custódio, Márcio R., 2007, Aplysina Nardo (Porifera, Verongida, Aplysinidae) from the Brazilian coast with description of eight new species, pp. 1-51 in Zootaxa 1609 on pages 35-36, DOI: 10.5281/zenodo.178878
title: Activité du port de Saint-Malo – 1703 – Port Blanc
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: produits de la mer
subject: produits manufacturés

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1703 avec le port "Port Blanc"
description: Marchandises au départ de Saint-Malo : huîtres
description: Catégories de marchandises au départ de Saint-Malo : produits de la mer
description: Marchandises arrivées à Saint-Malo : ustensiles
description: Catégories de marchandises arrivées à Saint-Malo : produits manufacturés
description: Coverage: Petit cabotage
description: Bibliographic citation: LABBÉ, Jeanne. L'Activité du port de Saint-Malo au début de la guerre de succession d'Espagne (1702-1703). DES : Histoire : Rennes, 1963 (Bibliothèque François-Lebrun, MH 1013)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Peromyscus difficilis J. A. Allen 1891
Creators: name: Wilson, Don E.
name: Reeder, DeeAnn
Publisher: name: The Johns Hopkins University Press
Year: 2005
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Peromyscus
Peromyscus difficilis

description: Peromyscus difficilis J. A. Allen 1891
Peromyscus difficilis J. A. Allen 1891, Bull. Am. Mus. Nat. Hist., 3: 298.
Type Locality: México, Zacatecas, Sierra de Valparaíso.
Vernacular Names: Southern Rock Deermouse.
Synonyms: Peromyscus amplus Osgood 1904; Peromyscus felipensis Merriam 1898; Peromyscus petricola Hoffmeister and de la Torre 1959; Peromyscus saxicola Hoffmeister and de la Torre 1959.
Distribution: W Chihuahua and SE Coahuila, south to C Oaxaca, México.
Conservation: IUCN – Lower Risk (lc).
Discussion: P. truei species group. Revised by Hoffmeister and de la Torre (1961) to include nasutus (see species account below) and comanche (transferred to P. truei —Schmidly, 1973). Karyologic and biochemical evidence has suggested that P. difficilis and P. nasutus are sibling species (Avise et al., 1979; Zimmerman et al., 1975, 1978); classified as such by Carleton (1989), but see Janecek (1990), who continued to view nasutus populations as part of P. difficilis. DeWalt et al. (1993 b) also noted the somewhat low levels of genetic divergence among attwateri, difficilis, and nasutus (e.g., less than P. gratus versus P. truei) but retained them as species, as did Tiemann-Boege et al. (2000). The matter of their synonymy merits reconsideration and decisive resolution. Gaona (1997) evaluated sex and age variation of populations in Veracruz and Puebla.
description: Published as part of Wilson, Don E. & Reeder, DeeAnn, 2005, Order Rodentia - Family Cricetidae, pp. 955-1189 in Mammal Species of the World: a Taxonomic and Geographic Reference (3 rd Edition), Volume 2, Baltimore :The Johns Hopkins University Press on page 1065, DOI: 10.5281/zenodo.7316535
FysikLAB præsentation om exoplaneter og astronomi ved Faaborg Gymnasium
Creators: name: Hinse, Tobias Cornelius
Publisher: name: Zenodo
Year: 2024

description: A 3 x 45 min in-depth presentation on astronomy, telescope, exoplanets and how to detect them (incl. a table-top demonstration of transiting planets and moons).
title: This-American-Life_2013-03-01_Transcription-Brute
Creators: name: Projet EMPHILINE
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2016

description: Provenance: Les données proviennent du site http://www.thisamericanlife.org
Oecetis acuticlasper Quinteiro & Holzenthal 2017
Creators: name: Neto, Pedro Bonfá
name: Vilarino, Albane
name: Salles, Frederico F.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Trichoptera
Leptoceridae
Oecetis
Oecetis acuticlasper

description: Oecetis acuticlasper Quinteiro & Holzenthal 2017
Distribution. Brazil (Espírito Santo, Minas Gerais, Rio de Janeiro).
Material examined. P13: 18–19.xi.2017 (1♁), 28.xii.2017 (1♁).
description: Published as part of Neto, Pedro Bonfá, Vilarino, Albane & Salles, Frederico F., 2023, Brevitentoria Weaver 1984 (Trichoptera: Integripalpia) of Espírito Santo State, Brazil: New records and new species, pp. 301-327 in Zootaxa 5336 (3) on page 318, DOI: 10.11646/zootaxa.5336.3.1, http://zenodo.org/record/8281432