cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Haversiella albolimbata
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Haversiella
Haversiella albolimbata

description: Haversiella albolimbata (Champion, 1918)
 Haversia albolimbata Champion, 1918a: 186 (type locality: Argentina: Falkland Islands (Islas Malvinas); type material: L: BMNH and PL: 1 BMNH).
 Haversiella albolimbata; Schweiger, 1959: 42.
 Host plants. Bryophytes (Morrone, 1994d).
 Distribution. Southern Argentina, including the Falkland Islands (Islas Malvinas), and southern Chile (Morrone, 1994d; Posadas, 2008).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on pages 25-26, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Development of the AG-MEMOD Country Level Agricultural Policy Analysis Tool in the New Members States of EU
Creators: name: Erjavec, Emil
name: Donnellan, Trevor
name: Erjavec, Emil
name: Donnellan, Trevor
Publisher: name: Unknown
Year: 2005
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: partial equilibrium modelling
subject: agriculture sector
subject: EU CAP reform
subject: EU Enlargement

description: This paper describes the development of modelling tools to simulate the effects of agricultural policy changes in New Member States (NMS) of the EU. Partial equilibrium models, developed as part of the AG-MEMOD (Agricultural Member State Modelling) Partnership, are used to simulate the effects of EU Accession and CAP Reform for countries that have recently joined and countries that may soon join the EU. Results show the effect of policy change scenarios on the main agricultural product markets such as grains, oilseeds, livestock and livestock products, as well as other significant components of agricultural output. Estimates can be provided for each year to a 10-year horizon. In the paper, the challenges faced in building agricultural policy models for economies, which have only recently completed the transition to a market basis, are described, along with some illustrative examples of key results. The development of these models for the NMS is a step towards their integration, on a more formal basis, with sister models which have already been developed for the EU15 Member States.
Additional file 6 of Optimization of tetramycin production in Streptomyces ahygroscopicus S91
Creators: name: Chen, Guang
name: Mengqiu Wang
name: Xianpu Ni
name: Huanzhang Xia
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 6: Figure S6. Cloning and overexpression of ttmD. a. Construction of the recombinant plamid p2ETD; b. PCR analysis of the multicope ttmD recombinant strains, M. DL2000, 1. S91-ΔNB::pETD/PB-1&TD-R (1.7k), 2. S91-ΔNB::p2ETD/PB-1&TD-R (1.7k), 3. S91-ΔNB::p3ETD/PB-1&TD-R (1.7k), 4. S91-ΔNB/PB-1&TD-R, 5. S91-ΔNB::pSET152/PB-1&TD-R.
Time-resolved connectome of the five-factor model of personality
Creators: name: Passamonti, L.
name: Riccelli, R.
name: Indovina, I.
name: Duggento, A.
name: Terracciano, A.
name: Toschi, N.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/631/378/2649/1725
/639/705/531
/59/36
/141
article

description: Abstract: The human brain is characterized by highly dynamic patterns of functional connectivity. However, it is unknown whether this time-variant ‘connectome’ is related to the individual differences in the behavioural and cognitive traits described in the five-factor model of personality. To answer this question, inter-network time-variant connectivity was computed in n = 818 healthy people via a dynamical conditional correlation model. Next, network dynamicity was quantified throughout an ad-hoc measure (T-index) and the generalizability of the multi-variate associations between personality traits and network dynamicity was assessed using a train/test split approach. Conscientiousness, reflecting enhanced cognitive and emotional control, was the sole trait linked to stationary connectivity across several circuits such as the default mode and prefronto-parietal network. The stationarity in the ‘communication’ across large-scale networks offers a mechanistic description of the capacity of conscientious people to ‘protect’ non-immediate goals against interference over-time. This study informs future research aiming at developing more realistic models of the brain dynamics mediating personality differences.
Additional file 7 of Optimization of tetramycin production in Streptomyces ahygroscopicus S91
Creators: name: Chen, Guang
name: Mengqiu Wang
name: Xianpu Ni
name: Huanzhang Xia
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 7: Table S1. Production analysis in S.ahygroscopicus S91 and its mutants.
Additional file 1 of Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer’s disease
Creators: name: Tissot, Cécile
name: L. Benedet, Andréa
name: Therriault, Joseph
name: Pascoal, Tharick A.
name: Lussier, Firoza Z.
name: Saha-Chaudhuri, Paramita
name: Chamoun, Mira
name: Savard, Melissa
name: Mathotaarachchi, Sulantha S.
name: Bezgin, Gleb
name: Wang, Yi-Ting
name: Fernandez Arias, Jaime
name: Rodriguez, Juan Lantero
name: Snellman, Anniina
name: Ashton, Nicholas J.
name: Karikari, Thomas K.
name: Blennow, Kaj
name: Zetterberg, Henrik
name: De Villers-Sidani, Etienne
name: Huot, Philippe
name: Gauthier, Serge
name: Rosa-Neto, Pedro
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 1: Supplementary Figure 1. Correlations maps (R-maps) of cross-sectional analyses, in both CU and CI groups. Supplementary Figure 2. Longitudinal changes of plasma pTau181 in each individual. Supplementary Figure 3. Longitudinal plasma pTau181 changes among cognitively unimpaired and cognitively impaired individuals, stratified by Aβ status.
The CAP Reform Impact on the Italian Durum Wheat Production: an Application of the AG-MEMOD Model
Creators: name: Esposti, Roberto
name: Lobianco, Antonello
name: Esposti, Roberto
name: Lobianco, Antonello
Publisher: name: Unknown
Year: 2005
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: Commodity Market Models
subject: Common Agricultural Policy
subject: Durum Wheat Market

description: This paper presents the results emerging from the application of alternative Common Agricultural Policy (CAP) scenarios into the Italian econometric country model, developed as part of the AG-MEMOD research project. Major attention is paid on the effect of the 2003 CAP reform on the Italian durum wheat production and a key role in shaping this impact is attributed to national choices. These concern the full or partial decoupling regime for the durum wheat supplementary payment, the introduction of the “quality premium” ex article 69 of the reform and the respective selective application. The implementation of these alternative CAP scenarios within the Italian AG-MEMOD model eventually confirms how critical national choices may be in determining the final outcome of the reform itself.
Additional file 3 of Intersecting sex-related inequalities in self-reported testing for and prevalence of Non-Communicable Disease (NCD) risk factors in Kerala
Creators: name: Negi, Jyotsna
name: Sankar D, Hari
name: Nair, Arun B.
name: Nambiar, Devaki
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3. Additional information on selected NCD risk indicators.
Exploring the antiviral activity of α-ketoamides compounds through electronic structure calculations: a structure-activity relationship study
Creators: name: Deienno, Augusto Cisconi
name: Gomes, Ramon Hernany Martins
name: Rossi, André Luis Debiaso
name: Simões, Rafael Plana
name: Batagin-Neto, Augusto
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: In recent years, the scientific community has worked intensively in the search and development of new drugs to suppress viral infections, such as COVID-19. In fact, a number of active compounds have been tested; however, the absence of significant structure-activity relationships hinders the production of optimized drugs. In this study, molecular modeling techniques were employed to investigate the electronic, structural and chemical reactivity properties of a set α-ketoamides whose antiviral activities have been reported in the literature, aiming to propose new promising derivatives. The local reactivity of the compounds was evaluated via condensed-to-atoms Fukui indexes and molecular electrostatic potential. Multivariate data analysis and random forests machine learning techniques were employed to correlate the antiviral properties and electronic and structural descriptors and identify relevant variables. A series of new derivatives were then proposed and evaluated via density functional theory-based calculations, and docking/molecular dynamics with the target protein of the virus. The results suggest that active derivatives present reduced reactivity towards electrophilic agents on the central core of the molecules and high reactivity on R1 ligands. Derivatives with higher predicted antiviral activities were proposed based on simple electronic descriptors, and their efficacies are reinforced by docking and molecular dynamics simulations.
Comparative trophic ecology of Cape anchovy Engraulis encrasicolus and Natal anchovy Stolephorus holodon off South Africa’s east coast
Creators: name: M Horton
name: CD Van Der Lingen
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The distributional ranges of Cape anchovy Engraulis encrasicolus and Natal anchovy Stolephorus holodon presently overlap at their eastern and western extremes, respectively, off South Africa’s east coast. These species might become more strongly sympatric as a consequence of changed distributions caused by climate change, possibly leading to intensified interspecific competition for trophic and other resources. A comparative analysis of the trophodynamics of the two species, which set out to assess elements of current niche partitioning between them, was conducted through morphological, dietary and stable-isotope analyses of specimens caught off South Africa’s east coast. Cape anchovy have larger gillraker spacing, gain the majority of their dietary carbon from large (>3 000 µm total length) planktonic crustaceans and occupy a higher trophic level than Natal anchovy, which have smaller gillraker spacing and gain the majority of their dietary carbon from planktonic crustaceans of two size classes (900–1 400 µm and 2 800–3 200 µm total length). These results indicate an element of trophic partitioning between the two species that will mitigate against interspecific competition.
Does Off-farm Employment Make Women in Rural Senegal Happy?
Creators: name: VAN DEN BROECK, Goedele
name: MAERTENS, Miet
name: VAN DEN BROECK, Goedele
name: MAERTENS, Miet
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Community/Rural/Urban Development
subject: International Development
subject: International Relations/Trade
subject: Labor and Human Capital
subject: Production Economics
subject: female employment
subject: subjective wellbeing
subject: globalization
subject: Senegal
subject: Sub-Saharan Africa

description: In this paper we investigate the impact of female wage employment in the Senegalese horticultural export industry on women’s wellbeing. We use a subjective wellbeing approach, based on self-reported happiness, to capture both income and non-income aspects of employment. We use original household- and individual-level survey data from the Saint-Louis region in Senegal and an instrumental variable approach. We find that female employment improves subjective wellbeing for the poorest women but not for women whose household income has moved well beyond the poverty threshold. Female employment improves women´s happiness through an income effect, as female employment leads to higher income levels and improved living standards, but the non-income effects of female employment reduce women’s happiness. This negative effect is related to a higher workload, low job satisfaction and changing gender roles. The positive income effect outweighs these negative non-income effects for poor women but not for relatively richer women.
description: Updated 14-July 2017
title: Diskriminierung in Organisationen. Eine qualitativ-rekonstruktive Studie
Creators: name: Macho-Pumpmeier, Franziska
Publisher: name: Pädagogische Hochschule Freiburg
Year: 2025
Subjects: subject: 300 Sozialwissenschaften

description: Anhand der Fragestellung ‚Wie wird Diskriminierung in Organisationen von Personen mit dem inhaltlichen Schwerpunkt Diskriminierung und Diversität verhandelt?‘ wurden zwei digitale Gruppendiskussionen mit Personen, die sich im Rahmen ihrer Beschäftigung mit Diskriminierung und/oder Diversität auseinandersetzen, durchgeführt, die mithilfe der Dokumentarischen Methode ausgewertet und rekonstruiert werden konnten. Die vorliegende Arbeit gründet folglich auf der Rekonstruktion von konjunktiven Erfahrungsräumen sowie impliziten Wissensbeständen, die sich in den Gruppendiskussionen zeigen. Auf Basis einer theoretischen Rahmung zu Diskriminierung sowie zu Organisationen im Kontext von Erwachsenen- und Weiterbildung werden die zentralen Ergebnisse eingeordnet. Diese bestehen in der Rekonstruktion der Orientierungen Zuständigkeitsklärung und Legitimierung und Eingebundenheit in machtvolle/hierarchische Praktiken und Handlungs(un)möglichkeiten anhand der ersten Fallbeschreibung und in der zweiten Fallbeschreibung der Orientierung Wirksamkeitsempfinden zwischen praktischen Handlungen und theoretischer Legitimation. In der Auswertung werden verschiedene Spannungsfelder sichtbar: zwischen Möglichkeiten und Grenzen des eigenen Handelns innerhalb von Orga-nisationen im Bereich Diskriminierung und Diversität, zwischen Praxis und Theorie, Wi-derstand und Anerkennung und zudem in der Eingebundenheit in Hierarchien und der Wirksamkeit innerhalb von Organisationen.
Sustainability of global and local food value chains. An empirical comparison of Peruvian and Belgian asparagus
Creators: name: Schwarz, Jana
name: Schuster, Monica
name: Annaert, Bernd
name: Maertens, Miet
name: Mathijs, Erik
name: Schwarz, Jana
name: Schuster, Monica
name: Annaert, Bernd
name: Maertens, Miet
name: Mathijs, Erik
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Community/Rural/Urban Development
subject: Environmental Economics and Policy
subject: International Development
subject: Production Economics
subject: local food value chains
subject: global food value chains
subject: food trade
subject: asparagus
subject: sustainability

description: The sustainability of food value chains is an increasing concern for consumers, food companies and policy-makers. Global food chains are often perceived to be less sustainable than local food chains. Yet, thorough food chain analyses and comparisons of different food chains across sustainability dimensions are rare. In this article we analyze the local Belgian and global Peruvian asparagus value chains and explore their sustainability performance. A range of indicators linked to environmental, economic and social impacts is calculated to analyze the contribution of the supply chains to economic development, resource use, labour relations, distribution of added value and governance issues. Our findings suggest that none of the two supply chains performs invariably better and that there are trade-offs among and between sustainability dimensions. Whereas the global chain uses water and other inputs more intensively and generates more employment per unit of land and higher yields; the local chain generates more revenue per unit of land.
description: See formal publication: Schwarz, J.; Schuster, M.; Annaert, B.; Maertens, M.; Mathijs, E. Sustainability of Global and Local Food Value Chains: An Empirical Comparison of Peruvian and Belgian Asparagus. Sustainability 2016, 8, 344.
Erdős-Ko-Rado theorems on the weak Bruhat lattice}
Creators: name: Fishel, Susanna
name: Hurlbert, Glenn
name: Kamat, Vikram
name: Meagher, Karen
Publisher: name: arXiv
Year: 2019
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05

description: Let ${\mathscr L}=(X,\preceq)$ be a lattice. For ${\cal P}\subseteq X$ we say that ${\cal P}$ is $t$-{\it intersecting} if ${\sf rank}(x\wedge y)\ge t$ for all $x,y\in{\cal P}$. The seminal theorem of Erdős, Ko and Rado describes the maximum intersecting ${\cal P}$ in the lattice of subsets of a finite set with the additional condition that ${\cal P}$ is contained within a level of the lattice. The Erdős-Ko-Rado theorem has been extensively studied and generalized to other objects and lattices. In this paper, we focus on intersecting families of permutations as defined with respect to the weak Bruhat lattice. In this setting, we prove analogs of certain extremal results on intersecting set systems. In particular we give a characterization of the maximum intersecting families of permutations in the Bruhat lattice. We also characterize the maximum intersecting families of permutations within the $r^{\textrm{th}}$ level of the Bruhat lattice of permutations of size $n$, provided that $n$ is large relative to $r$.
Hyperoides Marshall 1914
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Hyperoides

description: Hyperoides Marshall, 1914
 Hyperoides Marshall, 1914: 236 (type species: H. fragariae Marshall, 1914, by indication, monotypy); Marshall, 1930: 574 (= Listroderes); Morrone, 1993b: 18 (reinstated, revision).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 26, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Horticultural exports and food security in developing countries
Creators: name: VAN DEN BROECK, Goedele
name: MAERTENS, Miet
name: VAN DEN BROECK, Goedele
name: MAERTENS, Miet
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Community/Rural/Urban Development
subject: Consumer/Household Economics
subject: Crop Production/Industries
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: International Development
subject: Labor and Human Capital
subject: Production Economics
subject: high-value food exports
subject: food security
subject: poverty reduction
subject: agri-food system transformation
subject: contract-farming
subject: labor markets

description: This article reviews the channels through which horticultural exports affect food security in developing countries. We describe the trends in horticultural export chains and investigate the macro- and micro-level effects on the different components of food security, including availability, access, utilization and stability. The available evidence suggests that horticultural exports contribute to food security in developing countries, particularly through the development of rural labor markets and female wage employment in companies. Important challenges remain; most notably the provision of secure employment at remunerative conditions and the sustainable use of water resources. Private food standards may contribute to overcoming these challenges. Empirical evidence that directly measures the implications of horticultural exports on food security is highly needed.
description: An updated version of this working paper is published as: Van den Broeck, G., Maertens, M. (2016) Horticultural exports and food security in developing countries. Global Food Security, 10: 11-20.
Additional file 8 of Optimization of tetramycin production in Streptomyces ahygroscopicus S91
Creators: name: Chen, Guang
name: Mengqiu Wang
name: Xianpu Ni
name: Huanzhang Xia
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 8: Table S2. Strains, plasmids and primers used in this study.
3D-QSAR and ADMET studies of morpholino-pyrimidine inhibitors of DprE1 from Mycobacterium tuberculosis
Creators: name: Tayal, Sonali
name: Singh, Vasundhara
name: Bhatnagar, Sonika
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Molecular Biology
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Virology

description: DprE1 is involved in the synthesis of Mycobacterium tuberculosis cell wall and is a potent drug target for Tuberculosis (TB) treatment. The structure and dynamics of the loops L-I and L-II flanking the inhibitor binding site was studied using molecular dynamics (MD) simulation and MMPBSA in Amber v18. Docking and three-dimensional quantitative structure–activity relationship (3D-QSAR) of 55 Morpholino-pyrimidine (MP) inhibitors was carried out using Autodock v1.2.0 and Forge v10. ADMET analysis was done using SwissADME and pkCSM. All MP inhibitors docked in the DprE1 binding pocket, making contacts with L-II residues. MD studies showed that L-I and L-II unfold in the absence of the inhibitor but fold stably structure with reduced protein motions in the presence of MP-38, the highest affinity inhibitor. This was confirmed by k-means clustering and secondary structure analysis. L-II residues, L317, F320 and R325 contributed most towards the MMPBSA binding free energy of MP-38. A robust field-based 3D-QSAR model showed values of r2train = 0.982, r2test = 0.702 and q2 = 0.516. The MP inhibitor field points were broadly divided into negative electrostatics near the A, B rings and hydrophobic electrostatics near the D, E rings. Addition of negative groups at methanone position and ring B as well as addition of hydrophobic and bulky groups at ring E will improve activity. Highly active compounds 47, 49 and 50 of MP series exhibited highly favourable drug-like properties. SAR and ADMET insights attained from this model will help in the development of active DprE1 inhibitors in future.
High-Spectral Resolution Dark Holes: Concept, Results, and Promise
Creators: name: Thompson, William
name: Johnson, Adam
name: Marois, Christian
name: Lardiere, Olivier
name: Grandmont, Frederic
name: Hardy, Tim
name: Caputa, Kris
name: Bradley, Colin
name: Singh, Garima
Publisher: name: Proceedings of AO4ELT7 conference 2023 - Editors: Thierry Fusco and Benoit Neichel
Year: 2023
Subjects: HIGH CONTRAST IMAGING
FOCAL PLANE WAVEFRONT SENSING
SPECTROSCOPY
COHERENT DIFFERENTIAL IMAGING

description: Next generation high contrast imaging instruments face a challenging trade off: they will be required to deliver data with high spectral resolution at a fast cadence and across a wide field of view. For instruments that employ focal plane wavefront sensing and therefore require super-Nyquist sampling, these requirements cannot simultaneously be met with a traditional lenslet integral field spectrograph (IFU). For the SPIDERS pathfinder instrument, we are demonstrating an imaging Fourier transform spectrograph (IFTS) that offers a different set of tradeoffs than an IFU, delivering up to R20,000 spectral resolution across a dark hole. We present results from the SPIDERS IFTS including a chromaticity analysis of its dark hole and demonstrate a spectral differential imaging (SDI) improvement of up to 40A, and a first ever application of spectro-coherent differential imaging, combining both coherent differential imaging (CDI) and SDI.
Modelling Agricultural Abandonment: The Agri-Environmental Regulation Revisited
Creators: name: Fuentes-Castro, Daniel
name: Rambonilaza, Mbolatiana
name: Fuentes-Castro, Daniel
name: Rambonilaza, Mbolatiana
Publisher: name: Unknown
Year: 2005
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: CAP
subject: land abandonment
subject: multifunctional agriculture
subject: public policy
subject: rural development.

description: The article analyzes some regulatory mechanisms preventing agricultural abandonment by the introduction of some particular changes in the marginal benefits of farming. Two farming methods are considered: intensive and extensive. When the authors analyze the policy recovering the abandoned land with intensive farms they conclude that there exists a decoupled policy that maintains constant the agricultural revenue without any regulatory cost. When the authors analyze the policy recovering the abandoned land with extensive farms they conclude that recovering the abandoned land necessary requires the implementation of partial decoupled policies. The completely decoupled policies in the model require the substitution of intensive with extensive farms, and so the increase of the regulatory funds.
Screening of phytochemicals from Clerodendrum inerme (L.) Gaertn as potential anti-breast cancer compounds targeting EGFR: an in-silico approach
Creators: name: Yasmeen, Nusrath
name: Chaudhary, Anis Ahmad
name: Niraj, Ravi Ranjan K.
name: Lakhawat, Sudarshan S.
name: Sharma, Pushpender K.
name: Kumar, Vikram
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Breast cancer (BC) is the most prevalent malignancy among women around the world. The epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor (RTK) of the ErbB/HER family. It is essential for triggering the cellular signaling cascades that control cell growth and survival. However, perturbations in EGFR signaling lead to cancer development and progression. Hence, EGFR is regarded as a prominent therapeutic target for breast cancer. Therefore, in the current investigation, EGFR was targeted with phytochemicals from Clerodendrum inerme (L.) Gaertn (C. inerme). A total of 121 phytochemicals identified by gas chromatography-mass spectrometry (GC-MS) analysis were screened against EGFR through molecular docking, ADMET analyses (Absorption, Distribution, Metabolism, Excretion, and Toxicity), PASS predictions, and molecular dynamics simulation, which revealed three potential hit compounds with CIDs 10586 [i.e. alpha-bisabolol (−6.4 kcal/mol)], 550281 [i.e. 2,(4,4-Trimethyl-3-hydroxymethyl-5a-(3-methyl-but-2-enyl)-cyclohexene) (−6.5 kcal/mol)], and 161271 [i.e. salvigenin (−7.4 kcal/mol)]. The FDA-approved drug gefitinib was used to compare the inhibitory effects of the phytochemicals. The top selected compounds exhibited good ADMET properties and obeyed Lipinski’s rule of five (ROF). The molecular docking analysis showed that salvigenin was the best among the three compounds and formed bonds with the key residue Met 793. Furthermore, the molecular mechanics generalized born surface area (MMGBSA) calculations, molecular dynamics simulation, and normal mode analysis validated the binding affinity of the compounds and also revealed the strong stability and compactness of phytochemicals at the docked site. Additionally, DFT and DOS analyses were done to study the reactivity of the compounds and to further validate the selected phytochemicals. These results suggest that the identified phytochemicals possess high inhibitory potential against the target EGFR and can treat breast cancer. However, further in vitro and in vivo investigations are warranted towards the development of these constituents into novel anti-cancer drugs.
Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer
Creators: name: Pavanello, Marina
name: Chan, Isaac HY
name: Ariff, Amir
name: Pharoah, Paul DP
name: Gayther, Simon A.
name: Ramus, Susan J.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: ovarian cancer risk
rare germline variants
susceptibility genes

description: A family history of ovarian or breast cancer is the strongest risk factor for epithelial ovarian cancer (EOC). Germline deleterious variants in the BRCA1 and BRCA2 genes confer EOC risks by age 80, of 44% and 17% respectively. The mismatch repair genes, particularly MSH2 and MSH6, are also EOC susceptibility genes. Several other DNA repair genes, BRIP1, RAD51C, RAD51D, and PALB2, have been identified as moderate risk EOC genes. EOC has five main histotypes; high-grade serous (HGS), low-grade serous (LGS), clear cell (CCC), endometrioid (END), and mucinous (MUC). This review examines the current understanding of the contribution of rare genetic variants to EOC, focussing on providing frequency data for each histotype. We provide an overview of frequency and risk for pathogenic variants in the known susceptibility genes as well as other proposed genes. We also describe the progress to-date to understand the role of missense variants and the different breast and ovarian cancer risks for each gene. Identification of susceptibility genes have clinical impact by reducing disease-associated mortality through improving risk prediction, with the possibility of prevention strategies, and developing new targeted treatments and these clinical implications are also discussed.
PSR J1124-5916: discovery of a young, energetic pulsar in the supernova remnant G292.0+1.8
Creators: name: Camilo, F.
name: Manchester, R. N.
name: Gaensler, B. M.
name: Lorimer, D. R.
name: Sarkissian, J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the discovery with the Parkes radio telescope of a pulsar associated with the ~ 1700 yr-old oxygen-rich composite supernova remnant G292.0+1.8. PSR J1124-5916 has period 135 ms and period derivative 7.4e-13, implying characteristic age 2900 yr, spin-down luminosity 1.2e37 erg/s, and surface magnetic field strength 1.0e13 G. Association between the pulsar and the synchrotron nebula previously identified with Chandra within this supernova remnant is confirmed by the subsequent detection of X-ray pulsations by Hughes et al. The pulsar's flux density at 1400 MHz is very small, S ~ 0.08 mJy, but the radio luminosity of Sd^2 ~ 2 mJy kpc^2 is not especially so, although it is one order of magnitude smaller than that of the least luminous young pulsar previously known. This discovery suggests that very deep radio searches should be done for pulsations from pulsar wind nebulae in which the central pulsed source is yet to be detected and possibly other more exotic neutron stars.
description: 5 pages, 1 figure, Latex, accepted for publication by ApJ Letters
A Type System for First-Class Layers with Inheritance, Subtyping, and Swapping
Creators: name: Inoue, Hiroaki
name: Igarashi, Atsushi
Publisher: name: arXiv
Year: 2019
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: Context-Oriented Programming (COP) is a programming paradigm to encourage modularization of context-dependent software. Key features of COP are layers---modules to describe context-dependent behavioral variations of a software system---and their dynamic activation, which can modify the behavior of multiple objects that have already been instantiated. Typechecking programs written in a COP language is difficult because the activation of a layer can even change objects' interfaces. Inoue et al. have informally discussed how to make JCop, an extension of Java for COP by Appeltauer et al., type-safe. In this article, we formalize a small COP language called ContextFJ$_{
Courses: Open Science, Research Data Management and Data Sharing
Creators: name: Lima, Juliana
Publisher: name: figshare
Year: 2019
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications
subject: 80799 Library and Information Studies not elsewhere classified
subject: 80706 Librarianship

description: List elaborated by Juliana Soares Lima. This content is an integral part of the online mini course on Research Data Management. The mini course is part of the ongoing master's research of the aforementioned librarian, under the guidance of Professor Maria Giovanna Guedes Farias, in the Post-graduation Program in Information Science at the Federal University of Ceará.
Hyperoides murinus
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Hyperoides
Hyperoides murinus

description: Hyperoides murinus (Germain, 1896)
 Listroderes murinus Germain, 1896: 821 (type locality: Chile: Cordillera Aculeo; type material: L: MHNS and PL: 4 MHNS and 1 NZAC).
 Hyperoides murinus; Morrone, 1993b: 23.
 Host plants. Senecio sp. (Asteraceae) (Morrone, 1993b).
 Distribution. Central Chile (Morrone, 1993b).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 26, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
In silico identification and characterization of small molecule binding to the CD1d immunoreceptor
Creators: name: Rathakrishnan, Prashanth
name: McShan, Andrew C.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Computational Biology

description: CD1 immunoreceptors are a non-classical major histocompatibility complex (MHC) that present antigens to T cells to elucidate immune responses against disease. The antigen repertoire of CD1 has been composed primarily of lipids until recently when CD1d-restricted T cells were shown to be activated by non-lipidic small molecules, such as phenyl pentamethyl dihydrobenzofuran sulfonate (PPBF) and related benzofuran sulfonates. To date structural insights into PPBF/CD1d interactions are lacking, so it is unknown whether small molecule and lipid antigens are presented and recognized through similar mechanisms. Furthermore, it is unknown whether CD1d can bind to and present a broader range of small molecule metabolites to T cells, acting out functions analogous to the MHC class I related protein MR1. Here, we perform in silico docking and molecular dynamics simulations to structurally characterize small molecule interactions with CD1d. PPBF was supported to be presented to T cell receptors through the CD1d F’ pocket. Virtual screening of CD1d against more than 17,000 small molecules with diverse geometry and chemistry identified several novel scaffolds, including phytosterols, cholesterols, triterpenes, and carbazole alkaloids, that serve as candidate CD1d antigens. Protein-ligand interaction profiling revealed conserved residues in the CD1d F’ pocket that similarly anchor small molecules and lipids. Our results suggest that CD1d could have the intrinsic ability to bind and present a broad range of small molecule metabolites to T cells to carry out its function beyond lipid antigen presentation.
Additional file 7 of Mechanism of Zn2+ regulation of cellulase production in Trichoderma reesei Rut-C30
Creators: name: Li, Ni
name: Li, Jing
name: Chen, Yumeng
name: Shen, Yaling
name: Wei, Dongzhi
name: Wang, Wei
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 7: Table S2. The changes of 58 GPCR genes [1] in response to Zn2+ stimulus, NS represented not significant, p adjust>0.05
Additional file 1 of Circulating mature granzyme B+ T cells distinguish Crohn’s disease-associated axial spondyloarthritis from axial spondyloarthritis and Crohn’s disease
Creators: name: Lefferts, Adam R.
name: Regner, Emilie H.
name: Stahly, Andrew
name: O’Rourke, Becky
name: Gerich, Mark E.
name: Fennimore, Blair P.
name: Scott, Frank I.
name: Freeman, Alison E.
name: Jones, Ken
name: Kuhn, Kristine A.
Publisher: name: figshare
Year: 2021
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1.
Rotating Black Hole Entropy from M5-branes
Creators: name: Benini, Francesco
name: Gang, Dongmin
name: Zayas, Leopoldo A. Pando
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We compute the superconformal index of 3d $\mathcal{N}=2$ superconformal theories obtained from $N$ M5-branes wrapped on a hyperbolic 3-manifold. Exploiting the 3d-3d correspondence, we use perturbative invariants of $SL(N,\mathbb{C})$ Chern-Simons theory to determine the superconformal index in the large $N$ limit, including corrections logarithmic in $N$. The leading order partition function provides a microscopic foundation for the entropy function of the dual rotating asymptotically AdS$_4$ black holes. We also verify that the supergravity one-loop contribution to the $\log N$ term coincides with the field theoretic result. We propose a 3d-3d formulation for the refined topologically twisted index, and provide strong evidence in support of its vanishing --- which agrees with the fact that the expected dual rotating magnetically-charged black hole does not exist. This provides an interesting link between gravity and a tantalizing mathematical result.
description: 36 pages; v2: improved version with many clarifications; v3: published version
ანგლიციზმი ქართულ მედიაში
Creators: name: Mosashvili, Gia
Publisher: name: figshare
Year: 2019
Subjects: subject: Linguistics
subject: FOS: Languages and literature
subject: 200401 Applied Linguistics and Educational Linguistics

description: კვლევა ‘ანგლიციზმი ქართულ მედიაში’ სვამს საკითხს ქართულ ენაში ანგლიციზმის გზრდილი მასშტაბების შესახებ, რასაც ქართული მედიასაშუალებები მნიშვნელოვნად აძლევენ ხელს. ანგლიციზმი არა მხოლოდ საქართველოში, არამედ სხვა ქვეყნებშიც აქტუალური პრობლემაა. ქართველი ჟურნალისტები ინგლისური ტერმინებისა და ზოგადად უცხოური ტერმინების გამოყენებას არ ერიდებიან, შესაბამისად, არც ცდილობენ ამ ტერმინების ქართული სიტყვებით ჩანაცვლებას. გამონაკლისია პოლიტიკური და სხვა საერთაშორისო ტერმინები, რომლის ქართული ანალოგები ხშირად არ გვაქვს, ამიტომ სხვა გზა არც რჩება. თუმცა გამოყენება უცხოური სიტყვებისა იმის ფონზე, რომ მისი ქართული შესატყვისები არსებობს, პრობლემას კიდევ უფრო ამწვავებს - ეს ძირითადმა კვლევამაც დაადასტურა. ძირითად კვლევაში ქართული მედიასაშუალებების სხვადასხვა გადაცემების ანალიზმა აჩვენა, რომ ზომების მიღებაა საჭირო. ეს მხოლოდ ანგლიციზმს არ ეხება, ასევე საუბარია გრამატიკულ შეცდომებზეც, რომელსაც ნეოლოგიზმების დამკვიდრება იწვევს. ნაშრომის დასკვნით ნაწილში რეკომენდაციებია წარმოდგენილი.
Assessment of Simulation Behavior of Different Mathematical Programming Approaches
Creators: name: Gocht, Alexander
name: Gocht, Alexander
Publisher: name: Unknown
Year: 2005
Subjects: subject: Agricultural and Food Policy
subject: Research Methods/ Statistical Methods
subject: PMP
subject: ex-post evaluation
subject: FADN

description: This paper investigates the simulation behaviour of different PMP methods being developed in the past. About 800 of identical farms for eight years from the German FADN 1 were used to aggregate 45 farm groups. The aggregated farms were calibrated for 1996/97 and the observed prices, direct payments and yields for 2002/03 were applied. The ex-post simulation results underline that the simulation behaviour is mainly controlled by the considered PMP methodology. Even the Maximum Entropy approach proposed by Paris and Howitt (1998) for one observation on base year allocation did not improve the findings. In addition first experiences with an alternative model to PMP where the Q matrix is recovered using multiple observation proposed by Heckelei and Wolff (2003) are illustrated for one particular farm.
Space of kink solutions in SU(N)\times Z_2
Creators: name: Pogosian, Levon
name: Vachaspati, Tanmay
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We find $(N+1)/2$ distinct classes (``generations'') of kink solutions in an $SU(N)\times Z_2$ field theory. The classes are labeled by an integer $q$. The members of one class of kinks will be globally stable while those of the other classes may be locally stable or unstable. The kink solutions in the $q^{th}$ class have a continuous degeneracy given by the manifold $Σ_q=H/K_q$, where $H$ is the unbroken symmetry group and $K_q$ is the group under which the kink solution remains invariant. The space $Σ_q$ is found to contain incontractable two spheres for some values of $q$, indicating the possible existence of certain incontractable spherical structures in three dimensions. We explicitly construct the three classes of kinks in an SU(5) model with quartic potential and discuss the extension of these ideas to magnetic monopole solutions in the model.
description: 11 pages, 3 figures. Several minor changes made. Matches the version accepted to PRD
Activity time series of old stars from late F to early K. I. Simulating radial velocity, astrometry, photometry, and chromospheric emission
Creators: name: Meunier, N.
name: Lagrange, A. -M.
name: Boulet, T.
name: Borgniet, S.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Solar simulations and observations show that the detection of long-period Earth-like planets is expected to be very difficult with radial velocity techniques in the solar case because of activity. The inhibition of the convective blueshift in active regions (which is then dominating the signal) is expected to decrease toward lower mass stars, which would provide more suitable conditions. In this paper we build synthetic time series to be able to precisely estimate the effects of activity on exoplanet detectability for stars with a wide range of spectral type (F6-K4) and activity levels (old main-sequence stars). We simulated a very large number of realistic time series of radial velocity, chromospheric emission, photometry, and astrometry. We built a coherent grid of stellar parameters that covers a wide range in the (B-V, LogR'HK) space based on our current knowledge of stellar activity, to be able to produce these time series. We describe the model and assumptions in detail. We present first results on chromospheric emission. We find the average LogR'HK to correspond well to the target values that are expected from the model, and observe a strong effect of inclination on the average LogR'HK (over time) and its long-term amplitude. This very large set of synthetic time series offers many possibilities for future analysis, for example, for the parameter effect, correction method, and detection limits of exoplanets.
description: 20 pages, 15 figures Accepted in Astronomy & Astrophysics 18 March 2019
Hyperoides subcinctus
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Hyperoides
Hyperoides subcinctus

description: Hyperoides subcinctus (Boheman, 1842)
 Listroderes subcinctus Boheman, 1842: 193 (type locality: Chile: Valparaíso; type material: H: NHRS).
 Listroderes cinerascens Blanchard, 1851: 348 (type locality: Chile: Santa Rosa; type material: H: MNHN); Kuschel, 1955: 289 (= L. subcinctus).
 Listroderes incertus Germain, 1896: 808 (type locality: Chile: Mininco; type material: L: MHNS and PL: 16 MHNS); Kuschel, 1986: 115 (= L. subcinctus).
 Listroderes vulgaris Germain, 1896: 812 (type locality: Chile: Colina; type material: L: MHNS and PL: 15 MHNS); Kuschel, 1946: 139 (= L. subcinctus).
 Listroderes spoliatus Germain, 1896: 817 (type locality: Chile; type material: L: MHNS and PL: 7 MHNS); Kuschel, 1986: 115 (= L. subcinctus).
 Listroderes succinctus Kuschel, 1950: 14 (lapsus).
 Hyperoides subcinctus; Morrone, 1993b: 21.
 Host plants. Citrulus vulgaris Schrad. (Cucurbitaceae), Phaseolus sp. (Fabaceae), and Solanum tuberosum L. (Solanaceae) (Morrone, 1993b; Lanteri et al., 2002).
 Distribution. Southern Argentina and central Chile (Morrone, 1993b).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 26, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Additional file 4 of Intersecting sex-related inequalities in self-reported testing for and prevalence of Non-Communicable Disease (NCD) risk factors in Kerala
Creators: name: Negi, Jyotsna
name: Sankar D, Hari
name: Nair, Arun B.
name: Nambiar, Devaki
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 4. Additional information on the study design, sampling methodology and data collection.