cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Behavioral Characterization of a Knock-in Mouse Model of Huntington's Disease
Creators: name: Minnig, Shawn
Publisher: name: Western Washington University
Year: 2016

description:
Huntington’s disease (HD) is a progressive, fatal neurodegenerative disease caused by an inherited CAG expansion on the Huntingtin (HTT) gene resulting in cognitive, affective, and motor related symptoms. Although clinical diagnosis depends on the presence of Huntington’s chorea, a movement disorder consisting of irregular movements, cognitive symptoms appear 10-15 years prior during the pre-manifest stage of the disease and are more debilitating to patients. One of the most important advances in HD research has been the generation of mouse models that recapitulate the features of human HD, allowing researchers to identify the pathogenic mechanisms associated with the disease and test the potential therapeutic treatments. Unfortunately, many treatments that have been successful in mouse models have failed to translate to humans when tested in pre-clinical trials. This is partly because experimenters have largely focused on improving late-stage features of HD such as cell death and motor dysfunction, and utilized transgenic mouse that are severely impaired but poorly reproduce the pathogenic processes that underlie the disease. In contrast, knock-in (KI) mouse models are genetically faithful to the human condition but remain underutilized in pre-clinical research due to their slower progression and subtle overt phenotype. This thesis characterized the behavioral deficits associated with the HttQ111/+ KI mouse model of HD and discovered novel cognitive phenotypes that are characteristic of the pre-manifest stage of the disease. At nine months of age, HttQ111/+ mice display improved procedural memory on the two-cue MWM, hypoactivity, reduced velocity, and increased anxiety during open field exploration, and intact spatial LTM with a reduction in the total number of investigations toward both objects during an object location task. Together, these tasks provide a number of robust behavioral phenotypes for use in pre-clinical research conducted in the HttQ111/+ mouse model of HD in the future.
title: Endangered Species Act Section 7 Programmatic Conference and Biological Opinion and Magnuson-Stevens Fishery Conservation and Management Act Essential Fish Habitat Consultation for Standard Local Operating Procedures for Endangered Species to fund actions under the Stafford Act Authorized or Carried Out by the Federal Emergency Management Agency in Oregon, Washington, and Idaho (FEMA Endangered Species Programmatic [FESP])
titleType: Other
Creators: name: United States. National Marine Fisheries Service. West Coast Region United States
name:  Federal Emergency Management Agency
Publisher: name: United States. National Marine Fisheries Service. West Coast Region United States,  Federal Emergency Management Agency.
Year: 2018

description: ESA Section 7 Consultation ; WCR-2016-6048
Additional file 2 of Genomic analysis of Staphylococcus aureus from the West African Dwarf (WAD) goat in Nigeria
Creators: name: Shittu, Adebayo Osagie
name: Taiwo, Fadekemi Funmilayo
name: Froböse, Neele Judith
name: Schwartbeck, Bianca
name: Niemann, Silke
name: Mellmann, Alexander
name: Schaumburg, Frieder
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 2: Table S2. Percentage and level of agreement between antibiotic susceptibility testing (AST) and WGS with representative S. aureus isolates (n = 37) from the WAD goat in Nigeria.
Additional file 1 of Population dynamics and genome-wide selection scan for dogs in Chernobyl
Creators: name: Dillon, Megan N.
name: Thomas, Rachael
name: Mousseau, Timothy A.
name: Betz, Jennifer A.
name: Kleiman, Norman J.
name: Reiskind, Martha O. Burford
name: Breen, Matthew
Publisher: name: figshare
Year: 2023
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. This file contains supplementary figures 1-3 including a plot of individual inbreeding coefficients, a breed PCA and plot of highest breed match, and a correlation plot for ROH measures compared to breed measures.
A generalization of the Barban-Davenport-Halberstam Theorem to number fields
Creators: name: Smith, Ethan
Publisher: name: arXiv
Year: 2012
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: For a fixed number field $K$, we consider the mean square error in estimating the number of primes with norm congruent to $a$ modulo $q$ by the Chebotarëv Density Theorem when averaging over all $q\le Q$ and all appropriate $a$. Using a large sieve inequality, we obtain an upper bound similar to the Barban-Davenport-Halberstam Theorem.
description: Preprint of an old paper
Additional file 2 of The effect of tidal forcing on biogeochemical processes in intertidal salt marsh sediments
Creators: name: Taillefert, Martial
name: Neuhuber, Stephanie
name: Bristow, Gwendolyn
Publisher: name: figshare
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geochemistry

description: Authors’ original file for figure 2
Additional file 18 of rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
Creators: name: Choi, Yu-Min
name: Kim, Dong Hyun
name: Jang, Junghwa
name: Choe, Won Hyeok
name: Kim, Bum-Joon
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 18. Materials and methods
Norms Establishment of the Diagnosis and Recommendation Integrated System at Preflowering in Pineapple (Ananas comosus L.) and Its Verification in Case of Nutrient Omission Trial by Two Consecutive Crops
Creators: name: Quoc, Khuong Nguyen
name: Nhi, Luu Thi Yen
name: Le Thanh, Quang
name: Thanh, Thanh Xuan Ly Ngoc
name: Le Vinh, Thuc
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: Plant Biology

description: This study was conducted to (i) establish the diagnosis and recommendation integrated system (DRIS) for the macronutrient and micronutrient status of pineapple at the preflowering stage and (ii) verify the reliability of the established norms for macronutrients. We collected 86 pineapple leaves at sites +1 and +3 from 86 fields of pineapples grown in acid sulfate soil (ASS) and analyzed their nutrient content. Findings revealed the establishment of 12 and 20 nutrient ratios for DRIS norms at pineapple leaf sites +1 and +3. Based on omission fertilization of N, P, K, Ca, and Mg at the first crop, the DRIS index of N, P, K, and Mg was inadequate in treatments lacking the corresponding nutrients, whereas the DRIS index in the treatment fully fertilized with N, P, K, Ca, and Mg was negative and lower at the +3 leaf position. In the second crop, the DRIS norms were highly reliable via the negative DRIS index when fertilizing without N, P, K, Ca, and Mg. By contrast, when fertilizing with N, P, K, Ca, and Mg, the DRIS index was positive or less negative. The DRIS norms established that position +3 is robust and suitable for evaluating the pineapple macronutrient status.
On Expressing and Monitoring Oscillatory Dynamics
Creators: name: Dluhoš, Petr
name: Brim, Luboš
name: Šafránek, David
Publisher: name: arXiv
Year: 2012
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Logic in Computer Science (cs.LO)
subject: Numerical Analysis (math.NA)
subject: Systems and Control (eess.SY)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: To express temporal properties of dense-time real-valued signals, the Signal Temporal Logic (STL) has been defined by Maler et al. The work presented a monitoring algorithm deciding the satisfiability of STL formulae on finite discrete samples of continuous signals. The logic has been used to express and analyse biological systems, but it is not expressive enough to sufficiently distinguish oscillatory properties important in biology. In this paper we define the extended logic STL* in which STL is augmented with a signal-value freezing operator allowing us to express (and distinguish) detailed properties of biological oscillations. The logic is supported by a monitoring algorithm prototyped in Matlab. The monitoring procedure of STL* is evaluated on a biologically-relevant case study.
description: In Proceedings HSB 2012, arXiv:1208.3151
Il complesso con pitture al centro della città di Shahr-e Gur (Firuzabad, Fars, Iran): uno studio archeologico e storico-artistico
Creators: name: Bartolucci, Matteo
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2020
Subjects: L-OR/16 Archeologia e storia dell'arte dell'India e dell'Asia centrale

description: Questo studio si propone di descrivere le strutture rinvenute durante lo scavo aperto all’interno dell’area centro-settentrionale della città antica di “Ardashir Khwarrah”, oggi conosciuta come “Shahr-e Gur”, nel distretto di Firuzabad, parte centro meridionale della provincia del Fars in Iran. Lo studio si concentra con particolare attenzione sulle pitture scoperte all’interno di un complesso riportato alla luce: pur se di enorme importanza, tali pitture non hanno ancora visto un inquadramento cronologico e funzionale anche per la difficoltà di interpretazione del contesto archeologico. Lo studio procede dunque in modo tale da raccogliere in modo sistematico le informazioni disponibili oggi disperse, descrivere analiticamente e studiare dal punto di vista storico-artistico e archeologico il complesso e successivamente passare all’indagine sulla materia, la tecnica e i soggetti delle raffigurazioni pittoriche.
A Barban-Davenport-Halberstam asymptotic for number fields
Creators: name: Smith, Ethan
Publisher: name: arXiv
Year: 2012
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: Let $K$ be a fixed number field, and assume that $K$ is Galois over $\qq$. Previously, the author showed that when estimating the number of prime ideals with norm congruent to $a$ modulo $q$ via the Chebotarëv Density Theorem, the mean square error in the approximation is small when averaging over all $q\le Q$ and all appropriate $a$. In this article, we replace the upper bound by an asymptotic formula. The result is related to the classical Barban-Davenport-Halberstam Theorem in the case $K=\qq$.
description: Preprint of an old paper
Additional file 3 of The effect of tidal forcing on biogeochemical processes in intertidal salt marsh sediments
Creators: name: Taillefert, Martial
name: Neuhuber, Stephanie
name: Bristow, Gwendolyn
Publisher: name: figshare
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geochemistry

description: Authors’ original file for figure 3
Additional file 4 of Genomic analysis of Staphylococcus aureus from the West African Dwarf (WAD) goat in Nigeria
Creators: name: Shittu, Adebayo Osagie
name: Taiwo, Fadekemi Funmilayo
name: Froböse, Neele Judith
name: Schwartbeck, Bianca
name: Niemann, Silke
name: Mellmann, Alexander
name: Schaumburg, Frieder
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 4: Table S4. Percentage and level of agreement between PCR and WGS in the detection of PVL and IEC genes from representative S. aureus isolates (n = 37) from the WAD goat in Nigeria.
On the distribution of Jacobi sums
Creators: name: Lu, Qing
name: Zheng, Weizhe
name: Zheng, Zhiyong
Publisher: name: arXiv
Year: 2013
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11T24 (Primary), 11K38, 14G15, 20G05 (Secondary)

description: Let $\mathbf{F}_q$ be a finite field of $q$ elements. For multiplicative characters $χ_1,\dots, χ_m$ of $\mathbf{F}_q^\times$, we let $J(χ_1,\dots, χ_m)$ denote the Jacobi sum. Nicholas Katz and Zhiyong Zheng showed that for $m=2$, the normalized Jacobi sum $q^{-1/2}J(χ_1,χ_2)$ ($χ_1χ_2$ nontrivial) is asymptotically equidistributed on the unit circle as $q\to \infty$, when $χ_1$ and $χ_2$ run through all nontrivial multiplicative characters of $\mathbf{F}_q^\times$. In this paper, we show a similar property for $m\ge 2$. More generally, we show that the normalized Jacobi sum $q^{-(m-1)/2}J(χ_1,\dots,χ_m)$ ($χ_1\dotsm χ_m$ nontrivial) is asymptotically equidistributed on the unit circle, when $χ_1,\dots, χ_m$ run through arbitrary sets of nontrivial multiplicative characters of $\mathbf{F}_q^\times$ with two of the sets being sufficiently large. The case $m=2$ answers a question of Shparlinski.
description: 18 pages. v3: fixed some typos; v2: improved some bounds
Additional file 17 of rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
Creators: name: Choi, Yu-Min
name: Kim, Dong Hyun
name: Jang, Junghwa
name: Choe, Won Hyeok
name: Kim, Bum-Joon
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 17. Figure S13. Site-directed mutagenesis to introduce a stop codon upstream of the rt269 region. A stop codon was inserted at 49 bp (887 bp) upstream of rt269 region (936 bp) by site-directed point mutation. Conversion from TAT to TAA (stop) prevented the translation of full-length Pol-RT269 region
PLS Regression Based on ATR-FTIR to Predict Organomineral Fertilizers Properties and Nutrient Pools
Creators: name: de Morais, Everton Geraldo
name: Maluf, Henrique José Guimarães Moreira
name: Silva, Carlos Alberto
name: de Paula, Leonardo Henrique Duarte
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Plant Biology

description: Enrichment of organic residues with mineral fertilizers is a sustainable route to produce high agronomic value organomineral fertilizers (OMFs). OMFs agronomic value was conditioned by the properties and nutrients pools accessed by chemical analysis. Partial least squares (PLS) regression based on infrared analysis is a fast and alternative technique to assess the properties of OMFs, while replacing laborious, non-environmental-friendly, time-consuming, and high-cost conventional lab analytical procedures. OMFs were produced by composting of mixtures of different proportions of low-grade and soluble P sources with chicken manure and coffee husk for 150 days. After composting, the OMFs were dried and analyzed for: pH in CaCl2, electrical conductivity, total contents of C, P, N, and K, and C soluble in water, as well as for fertilizer-P soluble in water, citric acid, and neutral ammonium citrate. The compost MAP-based OMFs had a greater agronomic value than low-grade rock P-based OMFs. PLS regression models based on the ATR-FTIR spectral signature were a suitable tool to predict all OMFs chemical properties and nutrient pools evaluated through lab conventional analytical procedures. The good performance, robustness, and non-random correlation of PLS regression models were attested by their high coefficient of determination (R2) to calibration (0.92–0.99), cross-validation (0.87–0.99), and prediction capacity (0.89–0.99) combined with the lowest values of the root-mean-square error (RMSE) and reduced values of R2 (0.19–0.44), and to high values of RMSE to y-randomization. PLS based on ATR-FTIR is a rapid and alternative chemometric approach to assess the properties and nutrients pools of OMFs.
Additional file 1: of Prevalence and antibiotic resistance of bacteria isolated from the cerebrospinal fluid of neurosurgical patients at Peking Union Medical College Hospital
Creators: name: Chang, Jian-bo
name: Wu, Hao
name: Wang, He
name: Ma, Bai-tao
name: Wang, Ren-zhi
name: Wei, Jun-ji
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Case report form. The character of Postoperative Central Nervous System Infections (PCNSIS). (DOCX 23 kb)
Substellar Companions to Seven Evolved Intermediate-Mass Stars
Creators: name: Sato, Bun'ei
name: Omiya, Masashi
name: Harakawa, Hiroki
name: Izumiura, Hideyuki
name: Kambe, Eiji
name: Takeda, Yoichi
name: Yoshida, Michitoshi
name: Itoh, Yoichi
name: Ando, Hiroyasu
name: Kokubo, Eiichiro
name: Ida, Shigeru
Publisher: name: arXiv
Year: 2012
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We report the detections of substellar companions orbiting around seven evolved intermediate-mass stars from precise Doppler measurements at Okayama Astrophysical Observatory. o UMa (G4 II-III) is a giant with a mass of 3.1 M_sun and hosts a planet with minimum mass of m_2sini=4.1 M_J in an orbit with a period P=1630 d and an eccentricity e=0.13. This is the first planet candidate (< 13 M_J) ever discovered around stars more massive than 3 M_sun. o CrB (K0 III) is a 2.1 M_sun giant and has a planet of m_2sini=1.5 M_J in a 187.8 d orbit with e=0.19. This is one of the least massive planets ever discovered around ~2 M_sun stars. HD 5608 (K0 IV) is an 1.6 M_sun subgiant hosting a planet of m_2sini=1.4 M_J in a 793 d orbit with e=0.19. The star also exhibits a linear velocity trend suggesting the existence of an outer, more massive companion. 75 Cet (G3 III:) is a 2.5 M_sun giant hosting a planet of m_2sini=3.0 M_J in a 692 d orbit with e=0.12. The star also shows possible additional periodicity of about 200 d and 1880 d with velocity amplitude of ~7--10 m/s, although these are not significant at this stage. nu Oph (K0 III) is a 3.0 M_sun giant and has two brown-dwarf companions of m_2sini= 24 M_J and 27 M_J, in orbits with P=530.3 d and 3190 d, and e=0.126 and 0.17, respectively, which were independently announced by Quirrenbach et al. (2011). The ratio of the periods is close to 1:6, suggesting that the companions are in mean motion resonance. We also independently confirmed planets around k CrB (K0 III-IV) and HD 210702 (K1 IV), which had been announced by Johnson et al. (2008) and Johnson et al. (2007a), respectively. All of the orbital parameters we obtained are consistent with the previous results.
description: 21 pages, 14 figures, accepted for publication in PASJ
Additional file 16 of rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
Creators: name: Choi, Yu-Min
name: Kim, Dong Hyun
name: Jang, Junghwa
name: Choe, Won Hyeok
name: Kim, Bum-Joon
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 16: Figure S12. Site-directed mutagenesis to introduce a stop codon downstream of the polymerase start region
Hybrid models of the cell cycle molecular machinery
Creators: name: Noel, Vincent
name: Grigoriev, Dima
name: Vakulenko, Sergei
name: Radulescu, Ovidiu
Publisher: name: arXiv
Year: 2012
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Systems and Control (eess.SY)
subject: Quantitative Methods (q-bio.QM)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Biological sciences

description: Piecewise smooth hybrid systems, involving continuous and discrete variables, are suitable models for describing the multiscale regulatory machinery of the biological cells. In hybrid models, the discrete variables can switch on and off some molecular interactions, simulating cell progression through a series of functioning modes. The advancement through the cell cycle is the archetype of such an organized sequence of events. We present an approach, inspired from tropical geometry ideas, allowing to reduce, hybridize and analyse cell cycle models consisting of polynomial or rational ordinary differential equations.
description: In Proceedings HSB 2012, arXiv:1208.3151
Characteristic classes of affine varieties and Plucker formulas for affine morphisms
Creators: name: Esterov, Alexander
Publisher: name: arXiv
Year: 2013
Subjects: subject: Algebraic Geometry (math.AG)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 14C17, 32M10, 14T05, 14M25, 14M10, 14N15

description: An enumerative problem on a variety $V$ is usually solved by reduction to intersection theory in the cohomology of a compactification of $V$. However, if the problem is invariant under a "nice" group action on $V$ (so that $V$ is spherical), then many authors suggested a better home for intersection theory: the direct limit of the cohomology rings of all equivariant compactifications of $V$. We call this limit the affine cohomology of $V$ and construct affine characteristic classes of subvarieties of a complex torus, taking values in the affine cohomology of the torus. This allows us to make the first steps in computing affine Thom polynomials. Classical Thom polynomials count how many fibers of a generic proper map of a smooth variety have a prescribed collection of singularities, and our affine version addresses the same question for generic polynomial maps of affine algebraic varieites. This notion is also motivated by developing an intersection-theoretic approach to tropical correspondence theorems: they can be reduced to the computation of affine Thom polynomials, because the fundamental class of a variety in the affine cohomology is encoded by the tropical fan of this variety. The first concrete answer that we obtain is the affine version of what were, historically speaking, the first three Thom poylnomials -- the Plucker formulas for the degree and the number of cusps and nodes of a projectively dual curve. This, in particular, classifies toric varieties, whose projective dual is a hypersurface, computes the tropical fan of the variety of double tangent hyperplanes to a toric variety, and describes the Newton polytope of the hypersurface of non-Morse polynomials of a given degree. We also make a conjecture on the general form of affine Thom polynomials -- a key ingredient is the $n$-ary fan, generalizing the secondary polytope.
description: 44 pages, the final version
Additional file 1 of Individual differences in the expansiveness of mental disorder concepts: development and validation of concept breadth scales
Creators: name: Tse, Jesse S. Y.
name: Haslam, Nick
Publisher: name: figshare
Year: 2023
Subjects: subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 1: Appendix A. Concept Breadth of mental disorder – Vertical scale (CB-V). Appendix B. Concept Breadth of mental disorder – Vertical scale – Short form (CB-V-S). Appendix C. Concept Breadth of mental disorder – Horizontal scale (CB-H)
title: Fine-scale Topoclimate Modeling and Climatic Treeline Prediction of Great Basin Bristlecone Pine (Pinus longaeva) in the American Southwest
Creators: name: Bruening, Jamis M.
Publisher: name: Western Washington University
Year: 2016

description:
Great Basin bristlecone pine (Pinus longaeva) and foxtail pine (Pinus balfouriana) are valuable paleoclimate resources due to the climatic sensitivity of their annually-resolved rings. Recent treeline research has shown that growing season temperatures limit tree growth at and just below the upper treeline. In the Great Basin, the presence of precisely dated remnant wood above modern treeline shows that this ecotone shifts at centennial timescales tracking long-term changes in climate; in some areas during the Holocene climatic optimum treeline was 100 meters higher than at present. Such phenomena has motivated this analysis; regional treeline position models built exclusively from climate data may identify characteristics specific to Great Basin treelines and inform future physiological studies, and provide a measure of climate sensitivity specific to bristlecone and foxtail pine treelines. This study implements a topoclimatic analysis—using topographic position to explain patterns in surface temperatures across complex mountainous terrain—to model treeline position of three semi-arid bristlecone and/or foxtail pine treelines in the Great Basin as a function of topographically modified climate variables calculated from in situ measurements. Results indicate: (1) the treelines used in this study require a growing season length of between 143 - 152 days and average temperature ranging from 5.5 - 7.6 °C, (2) site-specific treeline position models may be improved through topoclimatic analysis—specifically the inclusion of an integrated measure of climate rather than a growing season isotherm measured in degrees, (3) treeline position in the Great Basin is likely out of equilibrium with the current climate indicating a potential shift in the primary growth-limiting factor at the highest elevations where trees are found.
Additional file 4 of The effect of tidal forcing on biogeochemical processes in intertidal salt marsh sediments
Creators: name: Taillefert, Martial
name: Neuhuber, Stephanie
name: Bristow, Gwendolyn
Publisher: name: figshare
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geochemistry

description: Authors’ original file for figure 4
Additional file 6 of Genomic analysis of Staphylococcus aureus from the West African Dwarf (WAD) goat in Nigeria
Creators: name: Shittu, Adebayo Osagie
name: Taiwo, Fadekemi Funmilayo
name: Froböse, Neele Judith
name: Schwartbeck, Bianca
name: Niemann, Silke
name: Mellmann, Alexander
name: Schaumburg, Frieder
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Additional file 6: Table S6. Characterization and detection of selected antibiotic resistance and virulence genes (WGS) in S. aureus isolates from the WAD goat in Nigeria.
Additional file 15 of rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
Creators: name: Choi, Yu-Min
name: Kim, Dong Hyun
name: Jang, Junghwa
name: Choe, Won Hyeok
name: Kim, Bum-Joon
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 15: Figure S11. rt269L-type HBV infection activated phospho-mTOR and phospho-PI3K signals in HBx protein dependent manner. Western blot analysis of the phospho-PI3K and phospho-mTOR, and GAPDH. The relative intensity was analyzed. **p < 0.01, ***p < 0.001
Additional file 2 of Correction to: Assessment of the inclusion of vaccination as an intervention to reduce antimicrobial resistance in AMR national action plans: a global review
Creators: name: van Heuvel, Lotte
name: Caini, Saverio
name: Dückers, Michel L. A.
name: Paget, John
Publisher: name: figshare
Year: 2023
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional File 2
Radio astronomy with the Lunar Lander: opening up the last unexplored frequency regime
Creators: name: Wolt, Marc Klein
name: Aminaei, Amin
name: Zarka, Philippe
name: Schrader, Jan-Rutger
name: Boonstra, Albert-Jan
name: Falcke, Heino
Publisher: name: arXiv
Year: 2012
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The active broadband (1 kHz-100 MHz) tripole antenna now envisaged to be placed on the European Lunar Lander located at the Lunar South Pole allows for sensitive measurements of the exosphere and ionosphere, and their interaction with the Earths magnetosphere, solar particles, wind and CMEs and studies of radio communication on the moon, that are essential for future lunar human and science exploration. In addition, the lunar South pole provides an excellent opportunity for radio astronomy. Placing a single radio antenna in an eternally dark crater or behind a mountain at the south (or north) pole would potentially provide perfect shielding from man-made radio interference (RFI), absence of ionospheric distortions, and high temperature and antenna gain stability that allows detection of the 21 cm wave emission from pristine hydrogen formed after the big bang and into the period where the first stars formed. A detection of the 21 cm line from the moon at these frequencies would allow for the first time a clue on the distribution and evolution on mass in the early universe between the Epoch of Recombination and Epoch of Reionization (EoR). A single lunar radio antenna would also allow for studies of the effect of solar flares and Coronal Mass Ejections (CMEs) on the solar wind at distances close to earth (space weather) and would open up the study of low frequency radio events from planets such as Jupiter and Saturn, which are known to emit bright (kJy-MJy) radio emission below 30 MHz (Jester & Falcke, 2009). Finally, a single radio antenna on the lunar lander would pave the way for a future large lunar radio interferometer; not only will it demonstrate the possibilities for lunar radio science and open up the last unexplored radio regime, but it will also allow a determination of the limitations of lunar radio science by measuring the local radio background noise.
description: Accepted for publication in a special issue PSS - "Scientific Preparations for Lunar Exploration"
Additional file 1 of Biological motion perception in autism spectrum disorder: a meta-analysis
Creators: name: Todorova, Greta Krasimirova
name: Hatton, Rosalind Elizabeth Mcbean
name: Pollick, Frank Earl
Publisher: name: figshare
Year: 2021
Subjects: subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Search strategies and number of records per database. File includes the search strategies used for the extraction of the papers from the five electronic databases mentioned in text and a table with the number of records extracted from each.
Additional file 14 of rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
Creators: name: Choi, Yu-Min
name: Kim, Dong Hyun
name: Jang, Junghwa
name: Choe, Won Hyeok
name: Kim, Bum-Joon
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 14: Figure S10. rt269L-type HBV infection, in both genotype C and A, activated phospho-Akt and phospho-PI3K signals. Western blot analysis of the phospho-PI3K and phosphor-Akt, and GAPDH. The relative intensity was analyzed. **p < 0.01, ***p < 0.001
Minimal fields of canonical dimensionality are free
Creators: name: Weinberg, Steven
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is shown that in a scale-invariant relativistic field theory, any field $ψ_n$ belonging to the $(j,0)$ or $(0,j)$ representations of the Lorentz group and with dimensionality $d=j+1$ is a free field. For other field types there is no value of the dimensionality that guarantees that the field is free. Conformal invariance is not used in the proof of these results, but it gives them a special interest; as already known and as shown here in an appendix, the only fields in a conformal field theory that can describe massless particles belong to the $(j,0)$ or $(0,j)$ representations of the Lorentz group and have dimensionality $d=j+1$. Hence in conformal field theories massless particles are free.
description: 14 pages
Additional file 1 of A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus
Creators: name: Kirchner, Lennart
name: Müller, Volker
name: Averhoff, Beate
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Science Policy
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 1: Table S1.: Plasmids used in this study; Table S2.: Primers used in this study; Table S3.. Alignment of mtlD from Thermoanaerobacter kivui with the codon optimized mtlD for Thermus thermophilus; Figure S1.. Verification of the PCR-products and the generated pMKE2-PpilA4-206 and pMKE2-PpilA4-499 plasmids; Figure S2.. Verification of the PCR-products and restriction analyses of the generated pLK1-plasmids.
Differences in Perceived Importance of Preventative Services and Healthcare Provider Trust Among Hispanics
Creators: name: Gore, Jonathan James
Publisher: name: University of Nevada, Las Vegas
Year: 2016

description: The Hispanic population varies greatly in their risk factors, health outcomes and access to care by country of origin, level of education and language dominance (Vega & Amaro, 1994) (Fiscella, Franks, Doescher, & Saver, 2002b). The differences within the Hispanic population also extend to their knowledge and attitudes toward health choices and maintenance, where they receive their health information, and what they access to meet their health care needs. Subpopulations within the Hispanic community as defined by language dominance and nativity must be understood as separate and distinct so that the health needs of each can be adequately addressed. The Centers for Disease Control and Prevention (CDC) have recently begun using audience research data sources, the Scarborough Marketing Research Survey and the Multimedia Audience Research Systems (MARS) Consumer Healthcare Study, to better understand the target audiences of health communication messages and campaigns. This study seeks to evaluate the validity and representativeness of the MARS study and evaluate the relationship of Spanish language dominance and foreign birth on attitudes towards annual medical exams and vaccination as well as internet access. A two-tailed independent t-test demonstrates that the means of commonly used demographic variables are significantly different between the MARS survey and the commonly accepted Behavioral Risk Factor Surveillance System (BRFSS) survey. However, the usefulness of the MARS study remains and its representativeness and validity need further study. Linear regression demonstrates a relationship between both foreign birth(B=.011) and Spanish language dominance (B=.018) and considering an annual exam to be important (p=0.00). These two variables are also shown to be related to trust of physician to recommend vaccines (p=0.00). Binomial Logistic Regression demonstrates that Spanish language dominance decreases the likelihood of using wireless devices to access the internet while foreign birth increases the likelihood although the model's goodness of fit is lacking. The findings of this study may be used as additional evidence to support the use of these new data sources as well as to better understand the health behavior, attitude, and access disparities among Hispanics in the U.S regarding annual exams and vaccination.
Additional file 13 of rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
Creators: name: Choi, Yu-Min
name: Kim, Dong Hyun
name: Jang, Junghwa
name: Choe, Won Hyeok
name: Kim, Bum-Joon
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 13: Figure S9. Cell death in liver tissues of mice hydrodynamically injected with the mock, rt269L, or rt269I vector was detected by TUNEL assay (FITC-conjugated). Nuclei were stained with DAPI (blue)
Effects of delayed immune-response in tumor immune-system interplay
Creators: name: Caravagna, Giulio
name: Graudenzi, Alex
name: Antoniotti, Marco
name: Mauri, Giancarlo
name: d'Onofrio, Alberto
Publisher: name: arXiv
Year: 2012
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: Tumors constitute a wide family of diseases kinetically characterized by the co-presence of multiple spatio-temporal scales. So, tumor cells ecologically interplay with other kind of cells, e.g. endothelial cells or immune system effectors, producing and exchanging various chemical signals. As such, tumor growth is an ideal object of hybrid modeling where discrete stochastic processes model agents at low concentrations, and mean-field equations model chemical signals. In previous works we proposed a hybrid version of the well-known Panetta-Kirschner mean-field model of tumor cells, effector cells and Interleukin-2. Our hybrid model suggested -at variance of the inferences from its original formulation- that immune surveillance, i.e. tumor elimination by the immune system, may occur through a sort of side-effect of large stochastic oscillations. However, that model did not account that, due to both chemical transportation and cellular differentiation/division, the tumor-induced recruitment of immune effectors is not instantaneous but, instead, it exhibits a lag period. To capture this, we here integrate a mean-field equation for Interleukins-2 with a bi-dimensional delayed stochastic process describing such delayed interplay. An algorithm to realize trajectories of the underlying stochastic process is obtained by coupling the Piecewise Deterministic Markov process (for the hybrid part) with a Generalized Semi-Markovian clock structure (to account for delays). We (i) relate tumor mass growth with delays via simulations and via parametric sensitivity analysis techniques, (ii) we quantitatively determine probabilistic eradication times, and (iii) we prove, in the oscillatory regime, the existence of a heuristic stochastic bifurcation resulting in delay-induced tumor eradication, which is neither predicted by the mean-field nor by the hybrid non-delayed models.
description: In Proceedings HSB 2012, arXiv:1208.3151
Additional file 5 of The effect of tidal forcing on biogeochemical processes in intertidal salt marsh sediments
Creators: name: Taillefert, Martial
name: Neuhuber, Stephanie
name: Bristow, Gwendolyn
Publisher: name: figshare
Year: 2023
Subjects: subject: Geology
subject: FOS: Earth and related environmental sciences
subject: Geochemistry

description: Authors’ original file for figure 5
Effects of nano-void density, size, and spatial population on thermal conductivity: a case study of GaN crystal
Creators: name: Zhou, Xiaowang
name: Jones, Reese E.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The thermal conductivity of a crystal is sensitive to the presence of surfaces and nanoscale defects. While this opens tremendous opportunities to tailor thermal conductivity, a true "phonon engineering" of nanocrystals for a specific electronic or thermoelectric application can only be achieved when the dependence of thermal conductivity on the defect density, size, and spatial population is understood and quantified. Unfortunately, experimental studies of effects of nanoscale defects are quite challenging. While molecular dynamics simulations are effective in calculating thermal conductivity, the defect density range that can be explored with feasible computing resources is unrealistically high. As a result, previous work has not generated a fully detailed understanding of the dependence of thermal conductivity on nanoscale defects. Using GaN as an example, we have combined physically-motivated analytical model and highly-converged large scale molecular dynamics simulations to study effects of defects on thermal conductivity. An analytical expression for thermal conductivity as a function of void density, size, and population has been derived and corroborated with the model, simulations, and experiments.
Top-K Nodes Identification in Big Networks Based on Topology and Activity Analysis
Creators: name: Gurung, Sweta
Publisher: name: University of Nevada, Las Vegas
Year: 2016

description: Graphs and Networks have been the most researched topics with applications ranging from theoretical to practical fields, such as social media, genetics, and education. In many competitive environments, the most productive activities may be interacting with high-profile people, reading a much-cited article, or researching a wide range of fields such as the study on highly connected proteins. This thesis proposes two methods to deal with top-K nodes identification: centrality-based and activity-based methods for identifying top-K nodes. The first method is based on the topological structure of the network and uses the centrality measure called Katz Centrality; a path based ranking measure that calculates the local influence of a node as well as its global influence. It starts by filtering out the top-K nodes from a pool of network data using Katz Centrality. By providing a means to filter out unnecessary nodes based on their centrality values, one can focus more on the most important nodes. The proposed method was applied to various network data and the results showed how different parameter values lead to different numbers of top-K nodes. The second method incorporates the theory of heat diffusion. Each node in the network can act as the source of heat. The amount of heat diffused or received by the node depends on the number of activities it performs. There are two types of activities: Interactive and Non-Interactive. Interactive activities could be likes, comments, and shares whereas posting a status, tweets or pictures could be the examples of non-interactive activities. We applied these proposed methods on Instagram network data and compared the results with the other similar algorithms. The experiment results showed that our activity-based approach is much faster and accurate than the existing methods.
Images referenced in this thesis are included in the supplementary files.
Strategic Molecular Design to Engineer the Electron Affinity of Self-Assembling Organic Semiconductors
Creators: name: Zaugg, Kelly Nicole
Publisher: name: University of Nevada, Las Vegas
Year: 2016

description: Development of electron-accepting (n-type) semiconductors used in organic photovoltaic cells and field effect transistors has been an area of research with less advancement compared to their electron-donating (p-type) counterparts. Currently, the highest performing n-type semiconductor is a fullerene-based derivative (PCBM) with a favorable ELUMO of -4.08 eV. However, PCBM has limited absorption in the visible region and fixed electron affinity. This work focuses on the development of self-assembling n-type materials with controllable electronic properties by strategically lowering ELUMO to a level comparable to PCBM. Molecular design follows an acceptor-acceptor'-acceptor (A-A'-A) configuration; with A being two 2,3-dioctyloxyphenazine substituents connected to A' with a C-C triple bond. A' was altered to increase the electron deficiency using benzothiadiazole (BTD), naphthalene diimide (NDI), and perylene-tetracarboxylic diimide (PTCDI). Based on this molecular design, four new n-type materials (BTD-P, NDI-P-1, NDI-P-2, PTCDI-P) were successfully synthesized with low ELUMO values of -3.34 eV, -3.90 eV, -3.90, and -3.97 eV, respectively. Photophysical, thermal, and electrochemical properties were studied using UV-Visible absorption and fluorescence emission spectroscopy, differential scanning calorimetry, thermogravimetric analysis, and cyclic voltammetry. Theoretical evaluations were conducted to understand the experimental electronic properties. Charge-transfer (CT) was also used to test the accepting properties of the title molecules when paired with a pyrene donor. Successful CT results were seen using NDI-P-1, which were confirmed through UV-Vis and fluorescence spectroscopy. The morphology of the CT complex was studied with polarized optical microscopy (POM). Additionally, fluorescence resonance energy transfer (FRET) through organogelation was studied with BTD-P as a donor with NDI-P-2 as an acceptor. It was found that FRET was efficient even at low acceptor concentration of 5mole%. FRET results were characterized with fluorescence spectroscopy and POM.
MOESM8 of The NAD kinase OsNADK1 affects the intracellular redox balance and enhances the tolerance of rice to drought
Creators: name: Wang, Xiang
name: Li, Bin-Bin
name: Ma, Tian-Tian
name: Sun, Liang-Yu
name: Tai, Li
name: Hu, Chun-Hong
name: Liu, Wen-Ting
name: Li, Wen-Qiang
name: Chen, Kun-Ming
Publisher: name: figshare
Year: 2020
Subjects: subject: Space Science
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: Additional file 8 : Table S3. The primer sequences used in the study.