cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer
Creators: name: Huang, Leaf
name: Li, Shyh Dar
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: We have previously shown that the PEGylated LPD (liposome-polycation-DNA) nanoparticles were highly efficient in delivering siRNA to the tumor with low liver uptake. Its mechanism of evading the reticuloendothelial system (RES) is reported here. In LPD, nucleic acids were condensed with protamine into a compact core, which was then coated by two cationic lipid bilayers with the inner bilayer stabilized by charge-charge interaction (also called the supported bilayer). Finally, a detergent-like molecule, polyethylene glycol (PEG)-phospholipid is post-inserted into the lipid bilayer to modify the surface of LPD. The dynamic light scattering (DLS) data showed that LPD had improved stability compared to cationic liposomes after incubation with a high concentration of DSPE-PEG2000, which is known to disrupt the bilayer. LPD prepared with a multivalent cationic lipid, DSGLA, had enhanced stability compared to those containing DOTAP, a monovalent cationic lipid, suggesting that stronger charge-charge interaction in the supported bilayer contributed to a higher stability. Distinct nanoparticle structure was found in the PEGylated LPD by transmission electron microscopy, while the cationic liposomes were transformed into tubular micelles. Size exclusion chromatography data showed that approximately 60% of the total cationic lipids, which were located in the outer bilayer of LPD, were stripped off during the PEGylation; and about 20% of the input DSPE-PEG2000 was incorporated into the inner bilayer with about 10.6 mol% of DSPE-PEG2000 presented on the particle surface. This led to complete charge shielding, low liver sinusoidal uptake, and 32.5% injected dose delivered to the NCI-H460 tumor in a xenograft model.
Development of skeletal muscle and adipose tissues in neonatal dairy calves upon a maternal supplementation with essential fatty acids and conjugated linoleic acids
Creators: name: Dahl, Nina
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 500 Natural sciences
subject: 590 Zoological sciences
subject: 630 Agriculture

description: Neonatal calves, which dams were supplemented with essentially fatty acids (EFAs) or conjugated linoleic acids (CLAs) from late gestation until early lactation, were investigated. The supplemented fatty acids were increased in different muscle and adipose tissues of the five-day-old calves as a result of maternal transfer. While CLAs appeared to promote a switch from slow to fast fiber type, EFAs appeared to promote for example the adipocyte differentiation in intramuscular fat. Overall, no major effects of the altered fatty acid supply on muscle and adipose tissue development were observed.
Possibility of DCC formation in pp collisions at LHC energy via reaction-diffusion equation
Creators: name: Bagchi, Partha
name: Das, Arpan
name: Sengupta, Srikumar
name: Srivastava, Ajit M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: There are indications of formation of a thermalized medium in high multiplicity pp collisions at LHC energy. It is possible that such a medium may reach high enough energy density/temperature so that a transient stage of quark-gluon plasma, where chiral symmetry is restored, may be achieved. Due to rapid 3-dimensional expansion, the system will quickly cool undergoing spontaneous chiral symmetry breaking transition. We study the dynamics of chiral field, after the symmetry breaking transition, for such an event using reaction-diffusion equation approach which we have recently applied for studying QCD transitions in relativistic heavy-ion collisions. We show that the interior of such a rapidly expanding system is likely to lead to the formation of a single large domain of disoriented chiral condensate (DCC) which has been a subject of intensive search in earlier experiments. We argue that large multiplicity pp collisions naturally give rise to required boundary conditions for the existence of slowly propagating front solutions of reaction-diffusion equation with resulting dynamics of chiral field leading to the formation of a large DCC domain.
description: 17 pages, 3 figures
Photometric determination of the mass accretion rates of pre-main-sequence stars. VIII. Recent star formation in NGC 299
Creators: name: Vlasblom, Marissa
name: De Marchi, Guido
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We studied the properties of the young stellar populations in the NGC 299 cluster in the Small Magellanic Cloud using observations obtained with the Hubble Space Telescope in the $V, I$, and $Hα$ bands. We identified 250 stars with H$α$ excess exceeding 5 $σ$ and an equivalent width of the H$α$ emission line of at least 20 Å, indicating that these stars are still undergoing accretion and therefore represent bona fide pre-main-sequence (PMS) objects. For 240 of these stars, we derived the mass, age, and mass accretion rate by comparing the observed photometry with theoretical models. We find evidence for the existence of two populations of PMS stars, with median ages of 25 and 50 Myr respectively. The average mass accretion rate for these PMS stars is $\sim 5 \times 10^{-9}$ M$_\odot$ yr$^{-1}$, which is comparable to the values found in other low-metallicity, low-density clusters in the Magellanic Clouds, but is about a factor of three lower than those measured for stars of similar mass and age in denser Magellanic Cloud stellar regions. Our findings support the hypothesis that both the metallicity and density of the forming environment can affect the mass accretion rate and thus the star formation process in a region. A study of the spatial distribution of both massive stars and (low-mass) PMS objects reveals that the former are clustered near the nominal centre of NGC 299, whereas the PMS stars are rather uniformly distributed over the field. To explore whether the stars formed in an initially more diffuse or compact structure, we studied the cluster's stellar density profile. We find a core radius $r_c\simeq 0.6$ pc and a tidal radius $r_t\simeq 5.5$ pc, with an implied concentration parameter $c \simeq 1$, suggesting that the cluster could be dispersing into the field.
description: 14 pages, 11 figures, accepted for publication in A&A, final revisions included
Protein modifications in transcription elongation
Creators: name: Fuchs, Stephen M.
name: Strahl, Brian D.
name: Laribee, R. Nicholas
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Posttranslational modifications (PTMs) of proteins play essential roles in regulating signaling, protein-protein modifications and subcellular localization. In this review, we focus on posttranslational modification of histones and RNA polymerase II (RNAPII) and their roles in gene transcription. A survey of the basic features of PTMs is provided followed by a more detailed account of how PTMs on histones and RNAPII regulate transcription in the model organism Saccharomyces cerevisiae. We emphasize the interconnections between histone and RNAPII PTMs and speculate upon the larger role PTMs have in regulating protein function in the cell.
title: История графического дизайна и рекламы
Creators: name: ELS IPR BOOKS
Publisher: name: Ай Пи Ар Медиа
Year: 2023

description: В учебном пособии изложена теория возникновения графического дизайна и рекламы; приведены знания в области истории и теории искусств, истории и теории дизайна в профессиональной деятельности. Описаны произведения искусства и дизайна в широком культурно-историческом контексте в тесной связи с религиозными, философскими и эстетическими идеями конкретного исторического периода. Рассмотрены национальные школы графического дизайна и рекламы. Учебное пособие подготовлено в соответствии с требованиями, предъявляемыми к изучению дисциплин «Графический дизайн», «История дизайна», «История рекламы», и предназначено для студентов, обучающихся по специальностям среднего профессионального образования 42.02.01 «Реклама», 54.02.01 «Дизайн (по отраслям)» и профессии 54.01.20 «Графический дизайнер».
SUBARU and e-Merlin observations of NGC3718. Diaries of an SMBH recoil?
Creators: name: Markakis, K.
name: Dierkes, J.
name: Eckart, A.
name: Nishiyama, S.
name: Britzen, S.
name: García-Marín, M.
name: Horrobin, M.
name: Muxlow, T.
name: Zensus, J. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: NGC3718 is a LINER $L1.9$ galaxy, lying at a distance of about $\sim 17.4$ Mpc away from earth and its similarities with NGC5128 often award it the name "northern Centaurus A". We use high angular resolution ($\sim100$ mas) e-Merlin radio and SUBARU NIR ($\sim170$ mas) data, to take a detailed view of the processes taking place in its central region. In order to preserve some objectivity in our interpretation, we combine our results with literature values and findings from previous studies. Our NIR maps suggest, on one hand, that towards the stellar bulge there are no large scale absorption phenomena caused by the apparent dust lane and, on the other, that there is a significant (local) contribution from hot ($\sim1000$ K) dust to the nuclear NIR emission. The position where this takes place appears to be closer to the offset compact radio emission from our e-Merlin $6$ cm map, lying offset by $\sim4.25$ pc from the center of the underlying stellar bulge. The shape of the radio map suggests the presence of one (or possibly two, forming an X-shape) bipolar structure(s) $\sim1$ ($\sim0.6$) arcsec across, which combined with the balance between the gas and the stellar velocity dispersions and the presence of hard X-ray emission, point towards effects expected by AGN feedback. We also argue that NGC3718 has a "core" in its surface brightness profile, despite the fact that it is a gas-rich galaxy and we discuss its mixed photometric and spectroscopic characteristics. The latter combined with the observed spatial and radio offsets, the relative redshift between the broad and the narrow $H{\mathrmα}$ line, the limited star formation activity and AGN feedback, strongly imply the existence of an SMBH recoil. Finally, we discuss a possible interpretation, that could naturally incorporate all these findings into one physically consistent picture.
description: 18 pages, 18 figures, 3 tables, accepted for publications in A&A
Stellar Spiral Structures in Triaxial Dark Matter Haloes
Creators: name: Hu, Shaoran
name: Sijacki, Debora
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We employ very high resolution simulations of isolated Milky Way-like galaxies to study the effect of triaxial dark matter haloes on exponential stellar discs. Non-adiabatic halo shape changes can trigger two-armed grand-design spiral structures which extend all the way to the edge of the disc. Their pattern speed coincides with the inner Lindblad resonance indicating that they are kinematic density waves which can persist up to several Gyr. In dynamically cold discs, grand-design spirals are swing amplified and after a few Gyr can lead to the formation of (multi-armed) transient recurrent spirals. Stellar discs misaligned to the principal planes of the host triaxial halo develop characteristic integral shaped warps, but otherwise exhibit very similar spiral structures as aligned discs. For the grand-design spirals in our simulations, their strength dependence with radius is determined by the torque on the disc, suggesting that by studying grand-design spirals without bars it may be possible to set constraints on the tidal field and host dark matter halo shape.
description: 21 pages, 20 figures. MNRAS accepted
Internetplattformen zur Diagnostik von Lernverläufen von Schülerinnen und Schülern in Deutschland
Creators: name: Blumenthal, Stefan
name: Gebhardt, Markus
name: Förster, Natalie Gabriele
name: Souvignier, Elmar
Publisher: name: Verband Sonderpädagogik e.V. Würzburg
Year: 2022
Subjects: subject: 370 Education

description: Die Lernverlaufsdiagnostik ist ein wesentliches Element zur Prävention von Lernproblemen sowie zur Evaluation von Förderentscheidungen und bildet die Grundlage für datenbasierte pädagogische Entscheidungsfindungsprozesse. Obwohl positive Effekte für die Anwendung einer Lernverlaufsdiagnostik nach aktueller Studienlage auf die Leistung der Schülerinnen und Schüler nachgewiesen sind, ist ihre Anwendung noch nicht weit verbreitet. Aktuell zeigt sich, dass Lehrkräfte Schwierigkeiten damit haben, Lernverlaufsdaten zu interpretieren und adäquate Förderentscheidungen abzuleiten. Internetbasierte Systeme zur Planung, Durchführung und Interpretation von Lernverlaufsdaten können zur Anwendung von Lernverlaufsdiagnostik für Sonder- oder Regelschullehrkräfte eine Hilfe sein. In diesem Kontext werden die drei Internetplattformen www.lernlinie.de, www.levumi.de sowie www.quop.de vorgestellt. Kriteriengeleitet werden jeweils die Grundideen, die Umsetzung in der pädagogischen Praxis und die wissenschaftliche Fundierung der Internetplattformen herausgearbeitet.
Hydrodynamics in long-range interacting systems with center-of-mass conservation
Creators: name: Morningstar, Alan
name: O'Dea, Nicholas
name: Richter, Jonas
Publisher: name: arXiv
Year: 2023
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In systems with a conserved density, the additional conservation of the center of mass (dipole moment) has been shown to slow down the associated hydrodynamics. At the same time, long-range interactions generally lead to faster transport and information propagation. Here, we explore the competition of these two effects and develop a hydrodynamic theory for long-range center-of-mass-conserving systems. We demonstrate that these systems can exhibit a rich dynamical phase diagram containing subdiffusive, diffusive, and superdiffusive behaviors, with continuously varying dynamical exponents. We corroborate our theory by studying quantum lattice models whose emergent hydrodynamics exhibit these phenomena.
description: 8 + 6 pages, 4 + 3 figures
Analysis of the functional consequences of lethal mutations in mitochondrial translational elongation factors
Creators: name: Ueda, Takuya
name: Jones, Christie N.
name: Akama, Kenta
name: Spremulli, Linda L.
name: Christian, Brooke E.
name: Takeuchi, Nono
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Mammalian mitochondria synthesize a set of thirteen proteins that are essential for energy generation via oxidative phosphorylation. The genes for all of the factors required for synthesis of the mitochondrially-encoded proteins are located in the nuclear genome. A number of disease-causing mutations have been identified in these genes. In this manuscript, we have elucidated the mechanisms of translational failure for two disease states characterized by lethal mutations in mitochondrial elongation factor Ts (EF-Tsmt) and elongation factor Tu (EF-Tumt).
SUMMER LAND SURFACE TEMPERATURE SMALL-LOCAL VARIATION IN INTRO-URBAN ENVIRONMENT IN EL PASO, TX.pdf
Creators: name: MacTar Mohamed
Publisher: name: figshare
Year: 2020
Subjects: subject: Climate Science
subject: 40104 Climate Change Processes
subject: FOS: Earth and related environmental sciences
subject: 40105 Climatology (excl. Climate Change Processes)
subject: 49999 Earth Sciences not elsewhere classified
subject: 50204 Environmental Impact Assessment
subject: 50206 Environmental Monitoring
subject: Geophysics
subject: 40403 Geophysical Fluid Dynamics

description: this dissertation casts light on an important issue in understanding the effect of built environment, biophysical and demographical factors on the local LST. Mixed methodology (correlation, descriptive, and GWR) was used in order to address this issue. The outcomes and methods used in this dissertation will be a beneficial reference for close investigation of local climate in the El Paso urban area in future work.
title: Самоменеджмент
Creators: name: ELS IPR BOOKS
Publisher: name: Южно-Уральский технологический университет
Year: 2022

description: Данное пособие рассматривает основные положения и особенности самоменеджмента. Курс самоменеджмента является основополагающим для формирования у будущих руководителей и специалистов знаний и умений правильно распределять свое время, организовать рабочий день, а также для поддержания длительной трудовой и личной активности. Учебное пособие разработано в соответствие с программой дисциплины «Самоменеджмент» и предназначено для обучающихся всех форм обучения и направлений подготовки. Учебное пособие предназначено для работы студентов, обучающихся по экономическим, юридическим направлениям и специальностям в области управления, а также слушателям различных курсов повышения квалификации.
title: Role of Quantitative Chemical Shift MR Imaging and Chemical Shift Subtraction Technique in Discriminating Adenomatous from Non Adenomatous Adrenal Solid lesions
Creators: name: Ramadan, Adel
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Abdomen
subject: Urinary Tract / Bladder
subject: Oncology
subject: MR
subject: MR-Functional imaging
subject: Comparative studies
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To evaluate role of quantitative assessment of chemical shift MR imaging and chemical shift subtraction technique in differentiating adenomatous from non-adenomatous adrenal lesions and comparing their accuracy...
Interaction of α-synuclein with vesicles that mimic mitochondrial membranes
Creators: name: Yang, Yoo Jeong
name: Pielak, Gary J.
name: Zigoneanu, Imola G.
name: Haque, Md Emdadul
name: Krois, Alexander S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: α-Synuclein, an intrinsically-disordered protein associated with Parkinson’s disease, interacts with mitochondria, but the details of this interaction are unknown. We probed the interaction of α-synuclein and its A30P variant with lipid vesicles by using fluorescence anisotropy and 19F nuclear magnetic resonance. Both proteins interact strongly with large unilamellar vesicles whose composition is similar to that of the inner mitochondrial membrane, which contains cardiolipin. However, the proteins have no affinity for vesicles mimicking the outer mitochondrial membrane, which lacks cardiolipin. The 19F data show that the interaction involves α-synuclein’s N-terminal region. These data indicate that the middle of the N-terminal region, which contains the KAKEGVVAAAE repeats, is involved in binding, probably via electrostatic interactions between the lysines and cardiolipin. We also found that the strength of α-synuclein binding depends on the nature of the cardiolipin acyl side chains. Eliminating one double bond increases affinity, while complete saturation dramatically decreases affinity. Increasing the temperature increases the binding of wild-type, but not the A30P variant. The data are interpreted in terms of the properties of the protein, cardiolipin demixing within the vesicles upon binding of α-synuclein, and packing density. The results advance our understanding of α-synuclein’s interaction with mitochondrial membranes.
Longitudinale Analyse regionaler Amyloidablagerungen mit klinischen und genetischen Prädiktoren bei Personen mit präklinischer oder klinischer Alzheimer-Krankheit
Creators: name: Bugla, Keanu Akira
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 610 Medical sciences Medicine

description: In dieser Studie nutzten wir die Positronen-Emissions-Tomografie -Signalwerte von Amyloidablagerungen der Probanden aus den ADNI-Studien, um ein 4-Stadienmodell zu erstellen. Die Grundkohorte bestand aus 667 Probanden in unserer Grundstichprobe, von denen 436 Probanden nach 2 Jahren und 250 Probanden nach 4 Jahren eine Folgeuntersuchung hatten. Somit war die Beobachtung der Probanden aus unterschiedlichen Diagnosegruppen (kognitiv normal, mild kognitiv beeinträchtigt, Alzheimer-Krankheit) über einen gesamten Zeitraum von 4 Jahren möglich.
Red Supergiants as Cosmic Abundance Probes: The Magellanic Clouds
Creators: name: Davies, Ben
name: Kudritzki, Rolf-Peter
name: Gazak, Zach
name: Plez, Bertrand
name: Bergemann, Maria
name: Evans, Chris
name: Patrick, Lee
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Red Supergiants (RSGs) are cool (~4000K), highly luminous stars (L - 10^5 Lsun), and are among the brightest near-infrared (NIR) sources in star-forming galaxies. This makes them powerful probes of the properties of their host galaxies, such as kinematics and chemical abundances. We have developed a technique whereby metallicities of RSGs may be extracted from a narrow spectral window around 1μm from only moderate resolution data. The method is therefore extremely efficient, allowing stars at large distances to be studied, and so has tremendous potential for extragalactic abundance work. Here, we present an abundance study of the Large and Small Magellanic Clouds (LMC and SMC respectively) using samples of 9-10 RSGs in each. We find average abundances for the two galaxies of [Z]LMC = -0.37 +/- 0.14 and [Z]SMC = -0.53 +/- 0.16 (with respect to a Solar metallicity of Zsun=0.012). These values are consistent with other studies of young stars in these galaxies, and though our result for the SMC may appear high it is consistent with recent studies of hot stars which find 0.5-0.8dex below Solar. Our best-fit temperatures are on the whole consistent with those from fits to the optical-infrared spectral energy distributions, which is remarkable considering the narrow spectral range being studied. Combined with our recent study of RSGs in the Galactic cluster Per OB1, these results indicate that this technique performs well over a range of metallicities, paving the way for forthcoming studies of more distant galaxies beyond the Local Group.
description: ApJ, in press
The Impossibly Early Galaxy Problem
Creators: name: Steinhardt, Charles L.
name: Capak, Peter
name: Masters, Dan
name: Speagle, Josh S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The current hierarchical merging paradigm and $Λ$CDM predict that the $z \sim 4-8$ universe should be a time in which the most massive galaxies are transitioning from their initial halo assembly to the later baryonic evolution seen in star-forming galaxies and quasars. However, no evidence of this transition has been found in many high redshift galaxy surveys including CFHTLS, CANDELS and SPLASH, the first studies to probe the high-mass end at these redshifts. Indeed, if halo mass to stellar mass ratios estimated at lower-redshift continue to $z \sim 6-8$, CANDELS and SPLASH report several orders of magnitude more $M \sim 10^{12-13} M_\odot$ halos than are possible to have formed by those redshifts, implying these massive galaxies formed impossibly early. We consider various systematics in the stellar synthesis models used to estimate physical parameters and possible galaxy formation scenarios in an effort to reconcile observation with theory. Although known uncertainties can greatly reduce the disparity between recent observations and cold dark matter merger simulations, even taking the most conservative view of the observations, there remains considerable tension with current theory.
description: 10 pages, ApJ, in press
Altersabhängige Auswirkungen eines RAGE-Knockout auf den B6/J Mausstamm mit Fokus auf den subbasalen Nervenplexus der Cornea
Creators: name: Hosseini, Seyed Siyawasch Justus
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 610 Medical sciences Medicine

description: Das AGE/RAGE-System gilt als ein pathophysiologischer Mechanismus der diabetischen Neuropathie. Da altersabhängige Faktoren dieses Systems noch unverstanden sind, erfolgte ein Vergleich zwischen einem RAGE-Knockout und Kontrollstamm in verschiedenen Alterskohorten. Zusammenfassend zeigen die Untersuchungsergebnisse an diesem Mausmodell insbesondere im jungen Alter eine Beteiligung des AGE/RAGE-Systems an der Entwicklung einer Neuropathie.
title: Role of positron emission tomography/computed tomography (PET/CT) in screening metastasis of renal cell carcinoma
Creators: name: Afifi, Ahmad
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Screening
subject: Radiation therapy / Oncology
subject: Localisation
subject: PET-CT
subject: PET
subject: CT
subject: Oncology
subject: Kidney
subject: Abdomen
subject: Metastases

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To demonstrate the role that FDG PET-CT can play in screening of different sites for local and distant metastasis from primary renal cell carcinoma and enhance its advantages over other imaging modalities...
René Wyss, Die Egolzwiler Kultur / René Wyss, Die Pfyner Kultur
Creators: name: Meier-Arendt, Walter
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2023

description: Rezension zu: René Wyss, Die Egolzwiler Kultur. Aus dem Schweizerischen Landesmuseum, Heft 12. Zweite, stark veränderte Auflage. Verlag Paul Haupt, Bern 1971. 19 Seiten und 16 Tafeln. René Wyss, Die Pfyner Kultur. Aus dem Schweizerischen Landesmuseum, Heft 26. Verlag Paul Haupt, Bern 1970. 15 Seiten und 16 Tafeln.
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 51 Nr. 1 (1973)
Spin-stripe phase in a frustrated zigzag spin-1/2 chain
Creators: name: Pregelj, M.
name: Zorko, A.
name: Zaharko, O.
name: Nojiri, H.
name: Berger, H.
name: Chapon, L. C.
name: Arčon, D.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Motifs of periodic modulations are encountered in a variety of natural systems, where at least two rival states are present. In strongly correlated electron systems such behaviour has typically been associated with competition between short- and long-range interactions, e.g., between exchange and dipole-dipole interactions in the case of ferromagnetic thin films. Here we show that spin-stripe textures may develop also in antiferromagnets, where long-range dipole-dipole magnetic interactions are absent. A comprehensive analysis of magnetic susceptibility, high-field magnetization, specific heat, and neutron diffraction measurements unveils $β$-TeVO$_4$ as a nearly perfect realization of a frustrated (zigzag) ferromagnetic spin-1/2 chain. Strikingly, a narrow spin stripe phase develops at elevated magnetic fields due to weak frustrated short-range interchain exchange interactions possibly assisted by the symmetry allowed electric polarization. This concept provides an alternative route for the stripe formation in strongly correlated electron systems and may help understanding other widespread, yet still elusive, stripe-related phenomena.
description: accapted in Nature Communications
Products of Thermodynamic Parameters for the Generalized Charged Rotating Black Hole and the Reissner-Nordstrom Black Hole with Global Monopole
Creators: name: Majeed, Bushra
name: Jamil, Mubasher
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We investigate the thermodynamics of Kerr-Newman-Kasuya black hole and the Reissner-Nordstrom black hole with a global monopole on inner and outer horizons. Products of surface gravities, surface temperatures, Komar energies, electromagnetic potentials, angular velocities, areas, entropies, horizon radii and the irreducible masses at the Cauchy and the event horizons are calculated. It is observed that the product of surface gravities, surface temperature product and product of Komar energies, electromagnetic potentials and angular velocities at horizons are not universal quantities for these black holes. Products of areas and entropies at horizons are independent of masses of black holes. Heat capacity is calculated for the generalized charged rotating black hole and phase transition is observed, under certain conditions on r. ?E
description: 16 pages, 1 figure
Analysis of Aluminum Metal as Oxide layer on the surface of wafer in Microelectronics
Creators: name: E N, ganesh
Publisher: name: figshare
Year: 2022
Subjects: subject: 90699 Electrical and Electronic Engineering not elsewhere classified
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This article provides an overview of the application of anodized aluminum in microelectronics. Applications as power hybrid circuits, multilayer MCMs, and microwave dielectric isolators are also affected. Attention has also been paid to the application of nanostructured matrices for the development of nanoelements. The experimental research results of the Microelectronics Division (structure, technology and manufacturing of microelectronic components) are presented.
Mechanism of protein biosynthesis in mammalian mitochondria
Creators: name: Spremulli, Linda L.
name: Christian, Brooke E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Protein synthesis in mammalian mitochondria produces 13 proteins that are essential subunits of the oxidative phosphorylation complexes. This review provides a detailed outline of each phase of mitochondrial translation including initiation, elongation, termination, and ribosome recycling. The roles of essential proteins involved in each phase are described. All of the products of mitochondrial protein synthesis in mammals are inserted into the inner membrane. Several proteins that may help bind ribosomes to the membrane during translation are described, although much remains to be learned about this process. Mutations in mitochondrial or nuclear genes encoding components of the translation system often lead to severe deficiencies in oxidative phosphorylation, and a summary of these mutations is provided.
Mechanisms for quality control of misfolded transmembrane proteins
Creators: name: Houck, Scott A.
name: Cyr, Douglas M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: To prevent the accumulation of misfolded and aggregated proteins, the cell has developed a complex network of cellular quality control (QC) systems to recognize misfolded proteins and facilitate their refolding or degradation. The cell faces numerous obstacles when performing quality control on transmembrane proteins. Transmembrane proteins have domains on both sides of a membrane and QC systems in distinct compartments must coordinate to monitor the folding status of the protein. Additionally, transmembrane domains can have very complex organization and QC systems must be able to monitor the assembly of transmembrane domains in the membrane. In this review, we will discuss the QC systems involved in repair and degradation of misfolded transmembrane proteins. Also, we will elaborate on the factors that recognize folding defects of transmembrane domains and what happens when misfolded transmembrane proteins escape QC and aggregate.
Dipole-dipole interactions in confined planar geometries
Creators: name: Dobbertin, Helge
Publisher: name: Universität Rostock
Year: 2021
Subjects: subject: 530 Physics

description: This thesis investigates the dipole-dipole interactions of thermal atomic vapors that are confined by a planar surface or a nanocavity and subjected to near-resonant light. One focus is on the Casimir-Polder effect, an atom-wall interaction caused by thermal and quantum fluctuations. Furthermore, it is shown that the atom-atom interactions lead to density-dependent line shifts and broadenings beyond continuous electrodynamics models. They can be controlled by the properties of the nanocavity.
The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes
Creators: name: Schrum, Laura W.
name: Bonkovsky, Herbert L.
name: Hou, Weihong
name: Steuerwald, Nury M.
name: Tian, Qing
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The let-7 microRNA (miRNA) plays important roles in human liver development and disease such as hepatocellular carcinoma, liver fibrosis and hepatitis wherein oxidative stress accelerates the progression of these diseases. To date, the role of the let-7 miRNA family in modulation of heme oxygenase 1 (HMOX1), a key cytoprotective enzyme, remains unknown. Our aims were to determine whether let-7 miRNA directly regulates Bach1, a transcriptional repressor of the HMOX1 gene, and whether indirect up-regulation of HMOX1 by let-7 miRNA attenuates oxidant injury in human hepatocytes. The effects of let-7 miRNA on Bach1 and HMOX1 gene expression in Huh-7 and HepG2 cells were determined by real-time qRT-PCR, Western blot, and luciferase reporter assays. Dual luciferase reporter assays revealed that let-7b, let-7c, or miR-98 significantly decreased Bach1 3’-untranslated region (3’-UTR)-dependent luciferase activity but not mutant Bach1 3’-UTR-dependent luciferase activity, whereas mutant let-7 miRNA containing base complementarity with mutant Bach1 3’-UTR restored its effect on mutant reporter activity. let-7b, let-7c, or miR-98 down-regulated Bach1 protein levels by 50–70%, and subsequently up-regulated HMOX1 gene expression by 3–4 fold, compared with non-specific controls. Furthermore, Huh-7 cells transfected with let-7b, let-7c or miR-98 mimic showed increased resistance against oxidant injury induced by tert-butyl-hydroperoxide (tBuOOH), whereas the protection was abrogated by over-expression of Bach1. In conclusion, let-7 miRNA directly acts on the 3’-UTR of Bach1 and negatively regulates expression of this protein, and thereby up-regulates HMOX1 gene expression. Over-expression of the let-7 miRNA family members may represent a novel approach to protecting human hepatocytes from oxidant injury.
Influence of the pore structure on the catalytic performance of Rh-supported Zr-MOFs in the hydroformylation of olefins
Creators: name: Sun, Yanjun
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 540 Chemistry & allied sciences

description: Zirconium-based metal-organic frameworks (Zr-MOFs) of different pore sizes and structure were synthesized and used for the preparation of the Rh-supported catalysts. The catalytic performance was studied in the hydroformylation of olefins to the corresponding aldehydes. A series of n-alk-1-enes of different chain length and bulky olefins with different size was used to study the influence of the pore size and structure. The results show that the Zr-MOF-based catalysts are very active and show high aldehyde selectivity.
Universitätsbibliothek der TU Hamburg - Jahresbericht 2020
Creators: name: Feldsien-Sudhaus, Inken
Publisher: name: TUHH Universitätsbibliothek
Year: 2021
Subjects: subject: Bibliothek
subject: Pandemie
subject: Hamburg Open Science
classificationCode: 000
subject: Allgemeines, Wissenschaft
classificationCode: 020
subject: Bibliotheks- und Informationswissenschaft
classificationCode: 370
subject: Erziehung, Schul- und Bildungswesen

description: Jahresbericht der Universitätsbibliothek der Technischen Universität Hamburg für 2020.
description: Annual Report of the University Library of the Hamburg University of Technology for 2020.
Single photoelectron spin detection and angular momentum transfer in a gate defined quantum dot
Creators: name: Fujita, Takafumi
name: Morimoto, Kazuhiro
name: Kiyama, Haruki
name: Allison, Giles
name: Larsson, Marcus
name: Ludwig, Arne
name: Valentin, Sascha R.
name: Wieck, Andreas D.
name: Oiwa, Akira
name: Tarucha, Seigo
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Recent innovations in fabricating nanoscale confined spin systems have enabled investigation of fundamental quantum correlations between single quanta of photons and matter states. Realization of quantum state transfer from photon polarization to electron spin using gate defined quantum dots (QDs) may give evidence of preserved coherence of angular momentum basis states at the photon-spin interface. The interface would enlarge the concept of quantum information technology, in which single photogenerated electron spins are manipulated with the dots, but this remains a serious challenge. Here, we report the detection of single electron spins generated by polarized single photons via a double QD (DQD) to verify the angular momentum transfer from single photons to single electrons. Pauli spin blockade (PSB) is used to project the photoelectron spin state onto the up or down spin state. Our result promises the realization of coherent quantum state transfer and development of hybrid photon and spin quantum technology.
description: 20 pages, 5 figures
title: Diagnostic value of diffusion tensor imaging in amyotrophic lateral sclerosis patients
Creators: name: Kidzinski, Rafal
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Neuroradiology brain
subject: CNS
subject: MR
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Motility

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Amyotrophic lateral sclerosis (ALS) is a subtype of Motor Neuron Disease. The diagnosis of ALS is often problematic as it is based mainly on clinical presentation. Certainty of diagnosis is labeled definite, probable or possible. Objective and...
Impact of capacitance and tunneling asymmetries on Coulomb blockade edges and Kondo peaks in non-equilibrium transport through molecular quantum dots
Creators: name: Aligia, A. A.
name: Bas, P. Roura
name: Florens, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We investigate theorerically the non-equilibrium transport through a molecular quantum dot as a function of gate and bias voltage, taking into account the typical situation in molecular electronics. In this respect, our study includes asymmetries both in the capacitances and tunneling rates to the source and drain electrodes, as well as an infinitely large charging energy on the molecule. Our calculations are based on the out-of-equilibrium Non-Crossing-Approximation (NCA), which is a reliable technique in the regime under consideration. We find that Coulomb blockade edges and Kondo peaks display strong renormalization in their width and intensity as a function of these asymmetries, and that basic expectations from Coulomb blockade theory must be taken with care in general, expecially when Kondo physics is at play. In order to help comparison of theory to experiments, we also propose a simple phenomenological model which reproduces semi-quantitatively the Coulomb blockade edges that were numerically computed from the NCA in all regimes of parameters.
description: 9 pages, 8 figures
title: Magnetic resonance diffusion-weighted imaging in differentiating bland from malignant portal vein thrombus: our experience in Egyptian patients
Creators: name: Afifi, Ahmad
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Abdomen
subject: Liver
subject: Vascular
subject: MR
subject: MR-Diffusion/Perfusion
subject: Diagnostic procedure
subject: Comparative studies
subject: Cancer

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of this study was to determine the usefulness of non-invasive non contrast MRI DWI technique in differentiating benign from malignant PV thrombus which is affecting the management of the...
Interpreting the language of histone and DNA modifications
Creators: name: Strahl, Brian D.
name: Rothbart, Scott B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: A major mechanism regulating the accessibility and function of eukaryotic genomes are the covalent modifications to DNA and histone proteins that dependably package our genetic information inside the nucleus of every cell. Formally postulated over a decade ago, it is becoming increasingly clear that post-translational modifications (PTMs) on histones act singly and in combination to form a language or ‘code’ that is read by specialized proteins to facilitate downstream functions in chromatin. Underappreciated at the time was the level of complexity harbored both within histone PTMs and their combinations, as well as within the proteins that read and interpret the language. In addition to histone PTMs, newly-identified DNA modifications that can recruit specific effector proteins has raised further awareness that histone PTMs operate within a broader language of epigenetic modifications to orchestrate the dynamic functions associated with chromatin. Here, we highlight key recent advances in our understanding of the epigenetic language encompassing histone and DNA modifications and foreshadow challenges that lie ahead as we continue our quest to decipher the fundamental mechanisms of chromatin regulation.
Untersuchungen zur Psychoonkologie urologischer Tumorerkrankungen
Creators: name: Dräger, Désirée Louisê
Publisher: name: Universität Rostock
Year: 2019
Subjects: subject: 150 Psychology
subject: 610 Medical sciences Medicine

description: Es lässt sich trotz der hohen Inzidenz urologischer Tumorerkrankungen die empirische Evidenz zu psychosozialen Belastungen und Unterstützungsbedürfnissen im Behandlungsverlauf und bei psychoonkologischen Interventionen als gering beurteilen. In der Praxis zeigt sich, dass ein signifikanter Anteil von urologischen Krebspatienten emotional belastet ist und gezielter psychoonkologischer Behandlungen bedarf. Anzustreben wäre eine Klärung differenzierender Kriterien (Patient - Zeitpunkt - Intervention - Outcome), um zukünftig eine optimierte Behandlungsplanung und -zuweisung zu gewährleisten.
Equilibrium molecular dynamics evaluation of the solid-liquid friction coefficient: role of timescales
Creators: name: Oga, Haruki
name: Omori, Takeshi
name: Joly, Laurent
name: Yamaguchi, Yasutaka
Publisher: name: arXiv
Year: 2023
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Solid-liquid friction plays a key role in nanofluidic systems. Yet, despite decades of method development to quantify solid-liquid friction using molecular dynamics (MD) simulations, an accurate and widely applicable method is still missing. Here, we propose a method to quantify the solid-liquid friction coefficient (FC) from equilibrium MD simulations of a liquid confined between parallel solid walls. In this method, the FC is evaluated by fitting the Green-Kubo (GK) integral of the S-L shear force autocorrelation for the range of time scales where the GK integral slowly decays with time. The fitting function was derived based on the analytical solution considering the hydrodynamic equations in our previous work [H. Oga et al., Phys. Rev. Research 3, L032019 (2021)], assuming that the timescales related to the friction kernel and to the bulk viscous dissipation can be separated. By comparing the results with those of other equilibrium MD-based methods and those of non-equilibrium MD for a Lennard-Jones liquid between flat crystalline walls with different wettability, we show that the FC is extracted with excellent accuracy by the present method, even in wettability regimes where other methods become innacurate. We then show that the method is also applicable to grooved solid walls, for which the GK integral displays a complex behavior at short times. Overall, the present method extracts efficiently the FC for various systems, with easy implementation and low computational cost.
description: 22 pages, 6 Figures
Kinetics of extracellular ATP in mastoparan 7-activated human erythrocytes
Creators: name: Incicco, J. Jeremías
name: Espelt, María Victoria
name: Lazarowski, Eduardo R.
name: Leal Denis, María Florencia
name: Verstraeten, Sandra V.
name: Pignataro, Omar P.
name: Schwarzbaum, Pablo J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The peptide mastoparan 7 (MST7) stimulated ATP release in human erythrocytes. We explored intra- and extracellular processes governing the time-dependent accumulation of extracellular ATP (i.e., ATPe kinetics).
Cigarette smoke exposure reveals a novel role for the MEK/ERK1/2 MAPK pathway in regulation of CFTR
Creators: name: Cormet-Boyaka, Estelle
name: Tarran, Robert
name: Tyrrell, Jean
name: Xu, Xiaohua
name: Balsiger, Robert
name: Boyaka, Prosper N.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: CFTR plays a key role in maintenance of lung fluid homeostasis. Cigarette smoke decreases CFTR expression in the lung but neither the mechanisms leading to CFTR loss, nor potential ways to prevent its loss have been identified to date.
null effect of coffee husk ash on geotechnical properties of expansive soil
Creators: name: Atahu, Meskerem Kebede
Publisher: name: Universität Rostock
Year: 2020
Subjects: subject: 624 Structural and Environmental Engineering

description: Expansive soil is one of the widespread typical problematic soils that poses several challenges for civil engineers.Expansive soils are hard and strong when they dry out; swell and soften when the moisture content increases.Particularly roads built on expansive soil are susceptible to early damage due to the swelling and shrinkage characteristics of this soil under changing moisture conditions.This study consists of experimental studies on the treatment of expansive soil using Coffee husk ash (CHA).
title: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege, Bd. 54 Nr. 1 (2013): Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
title: Burgen und Schlösser. Zeitschrift für Burgenforschung und Denkmalpflege
titleType: AlternativeTitle
Creators: name: Burgen Und Schlösser-Zeitschrift Für Burgenforschung Und Denkmalpflege
Publisher: name: Burgen und Schlösser - Zeitschrift für Burgenforschung und Denkmalpflege
Year: 2021

description: Pfalz Werla – Die Ausgrabung von Tor II aus dem 10. Jahrhundert und seine Visualisierung 2012...2-8 Die Bramburg bei Hemeln, Ldkr. Göttingen (Niedersachsen)...31-39 Inhaltsverzeichnis 53. Jahrgang 2013 Winfried Mogge, „Dies uralt Haus auf Felsengrund…“, Rothenfels am Main: Geschichte und Gestalt einer unterfränkischen Burg...63-64 Baudenkmale gefährdet - Baudenkmale gerettet...52-62 Die Holsterburg bei Warburg: Überlegungen zur Vermessung der Anlage...50-51 Burg und Schloss Hachenburg – neue Erkenntnisse zur Baugeschichte der saynischen Residenz vor der barocken Umgestaltung ab 1719...40-49 Burg Stahleck am Rhein – „klassische“ Burg des frühen 12. Jahrhunderts...9-17 Impressum und Inhalt