cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Detection and Characterization of Micrometeoroids with LISA Pathfinder
Creators: name: Thorpe, James Ira
name: Parvini, Cameron
name: Trigo-Rodriguez, Josep
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The Solar System contains a population of dust and small particles originating from asteroids, comets, and other bodies. These particles have been studied using a number of techniques ranging from in-situ satellite detectors to analysis of lunar microcraters to ground-based observations of zodiacal light. In this paper, we describe an approach for using the LISA Pathfinder (LPF) mission as an instrument to detect and characterize the dynamics of dust particles in the vicinity of Earth-Sun L1. Launching in late 2015, LPF is a dedicated technology demonstrator mission that will validate several key technologies for a future space-based gravitational-wave observatory. The primary science instrument aboard LPF is a precision accelerometer which we show will be capable of sensing discrete momentum impulses as small as $4\times 10^{-8}\,\textrm{N}\cdot\textrm{s}$. We then estimate the rate of such impulses resulting from impacts of micrometeoroids based on standard models of the micrometeoroid environment in the inner solar system. We find that LPF may detect dozens to hundreds of individual events corresponding to impacts of particles with masses $> 10^{-9}\,$g during LPF's roughly six-month science operations phase in a $5\times 10^5\,\textrm{km}$ by $8\times 10^5\,\textrm{km}$ Lissajous orbit around L1. In addition, we estimate the ability of LPF to characterize individual impacts by measuring quantities such as total momentum transferred, direction of impact, and location of impact on the spacecraft. Information on flux and direction provided by LPF may provide insight as to the nature and origin of the individual impact and help constrain models of the interplanetary dust complex in general. Additionally, this direct in-situ measurement of micrometeoroid impacts will be valuable to designers of future spacecraft targeting the environment around L1.
description: 6 pages, 5 figures, submitted to Earth, Moon, and Planets
An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures
Creators: name: Williams, Tishan
name: Sapienza, Paul J.
name: Carter, Charles W.
name: Lee, Andrew L.
name: Li, Li
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Urzymes-short, active core modules derived from enzyme superfamilies-prepared from the two aminoacyl-tRNA synthetase (aaRS) Classes contain only the modules shared by all related family members. They have been described as models for ancestral forms. Understanding them depends on inferences drawn from the crystal structures of the full-length enzymes. As aaRS Urzymes lack much of the mass of modern aaRS, retaining only a small portion of the hydrophobic cores of the full-length enzymes, it is desirable to characterize their structures. We report preliminary characterization of 15N tryptophanyl-tRNA synthetase Urzyme by heteronuclear single quantum coherence (HSQC) NMR spectroscopy supplemented by circular dichroism, thermal melting, and induced fluorescence of bound dye. The limited dispersion of 1H chemical shifts (0.5 ppm) is inconsistent with a narrow ensemble of well-packed structures in either free or substrate-bound forms, although the number of resonances from the bound state increases, indicating a modest, ligand-dependent gain in structure. Circular dichroism spectroscopy shows the presence of alpha helix and evidence of cold denaturation, and all ligation states induce Sypro Orange fluorescence at ambient temperatures. Although the term "molten globule" is difficult to define precisely, these characteristics are consistent with most such definitions. Active-site titration shows that a majority of molecules retain ~60% of the transition state stabilization free energy observed in modern synthetases. In contrast to the conventional view that enzymes require stable tertiary structures, we conclude that a highly flexible ground-state ensemble can nevertheless bind tightly to the transition state for amino acid activation.
title: 5.-8. April 2022
Creators: name: Heseding, Hauke
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: Distributed denial of service||software defined networks||hierarchical heavy hitters||reinforcement learning

description: This work introduces a novel approach to combine hierarchical heavy hitter algorithms with reinforcement learning to mitigate evolving volumetric distributed denial of service attacks. The goal is to alleviate the strain on the network infrastructure through early ingress filtering based on compact filter rule sets that are evaluated by fast ternary content-addressable memory. The reinforcement learning agents task is to maintain effectiveness of established filter rules even in dynamic traffic scenarios while preserving limited memory resources. Preliminary results based on synthesized traffic scenarios modelling dynamic attack patterns indicate the feasibility of our approach.
RRR - Mazar_Srull - vanpaemel
Creators: name: vanpaemel, wolf
name: Claesen, Aline
name: Gomes, Sara
name: Verliefde, Thomas
name: tuerlinckx, francis
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: dsimons@illinois.edu

description: Our laboratory's Implementation of the Mazar_Srull RRR protocol
Barynotus (Barynotus) umbilicatus subsp. umbilicatus Dufour 1852
Creators: name: Delbol, Marc
name: Perez, Christian
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Barynotus
Barynotus umbilicatus
Barynotus (barynotus) umbilicatus umbilicatus dufour, 1852

description: Barynotus (Barynotus) umbilicatus umbilicatus Dufour, 1852
(Figs 40, 52, 61)
SYNONYME: Aucun.
 MATÉRIEL EXAMINÉ: France: " Aude ", sans localité ni date (1♂ et 1♀ RBINS Coll. Lavagne); " Pyrénées " sans localité ni date (1♂ RBINS Coll. Bourgoin), " Pyrénées " sans localité ni date (1♂ et 1♀ RBINS Coll. Bourgoin), " Pyrénées " sans localité ni date (2♀♀ Coll. CPJP); " Hautes-Pyrénées ", sans localité ni date (1♂ et 1♀ RBINS Coll. Roelofs), " Hautes-Pyrénées ", sans localité ni date (1♂ et 2♀♀ RBINS Coll. A. Fauvel); Hautes-Pyrénées, Arrens-Marsous sans date (2♂♂ et 2♀♀ RBINS Coll. Fauvel, ex. Coll. Pandellé), Gavarnie VII.1980 (2♀♀ Coll. CPDM), Gèdre "Cirque de Troumouse" 2.100 m. VI.2018 (1♂ Col. CPCP), Hèches, 1.000 m VIII.2004 (1♀ Coll. CPER, leg. H. Brustel), Bas-Nistos V.1991 (3♀♀ Coll. CPCV); Pyrénées-Atlantiques, Les Eaux Chaudes V.1996 (1♂ Coll. CPCP, leg. J. C. Freeman), Les Eaux Chaudes V.1996 (1♀ Coll. CPER), Larrau "Pic d’Orhy" VI.1983 (1♀ Coll. CPPP), Gourette VI.1978 (1♂ et 1♀ leg. G. Tiberghien, Coll. CPPC), Estérençuby "Bois d’Arpunta" VI.2016 (4♀ Coll. CPPC), Osse-en-Aspe "Forêt d’Issaux" VII.1978 (1♂ et 1♀ Coll. CPPC); Ariège, Salau "Cirque d’Anglade" 1.500 m. V.2015 (1♀ Coll. CPCP), Salau "Cirque d’Anglade" 1.500 m. VI.2018 (1♀ Coll. CPCP), Salau "Cirque d’Anglade" VI.1973 (1♂ 2♀♀ Coll. CPCV), Biert VIII-2012 (1♀ Coll. CPCV), Foix "L’Herm" VII.1974 (2♀♀ Coll. CPCV), Balaguères IV.1984 (1♀ Coll. CPCV), Bélesta V.1989 (1♀ Coll. CPCV); Lot, Cabrerets "Vallée de la Sagne" VII.2014 (1♂ Coll. CPER).
 DONNÉES COMMUNIQUÉES: France: "Pyrénées" sans localité ni date (1 ex. NMB coll. J. Breit); Hautes-Pyrénées, Hèches "Clot de chapeu" VI.2004 (9 ex. Coll. CPLV, leg. H. Brustel & L. Valladares), Hèches "Coume de Castilhou" VII.2004 (10 ex. Coll. CPLV, leg. H. Brustel & L. Valladares), Hèches VIII.2004 (1 ex. Coll. CPLS); Pyrénées-Atlantiques, Larrau VI.1955 (1 ex. Coll. CPJHY, leg. L. Levasseur), Laruns VI.1986 (1 ex. Coll. CPPD), Bielle V.2010 (3 ex. Coll. CPPD), Bilhères-en-Ossau VII.2010 (1 ex. Coll. CPPD; Aude, Camurac IX.2010 (1 ex. Coll. CPPF); Lot, Cabrerets "Vallée du Célé" II.1987 (1 ex. Coll. CPFB, det. J. Pericart), Marcilhac-sur-Célé IV.2004 (1 ex. Coll. CPDD).
DISTRIBUTION: Pyrénées françaises, Ariège, Aude, Lot.
 ETHOLOGIE: Inconnue, mais collecté sur Mercurialis perrenis L. par Didier Delpy dans le Lot à Marcilhac-sur-Célé.
description: Published as part of Delbol, Marc & Perez, Christian, 2020, Barynotus (Barynotus) mainardii mainardii F. Solari, espèce nouvelle pour la faune de France et notes sur le genre Barynotus Germar, 1817 (Curculionidae: Entiminae: Geonemini), pp. 1-31 in Belgian Journal of Entomology 94 on page 23, DOI: 10.5281/zenodo.13711026
title: Following excited-state chemical shifts in molecular ultrafast x-ray photoelectron spectroscopy
Creators: name: Mayer, Dennis
name: Lever, Fabiano
name: Picconi, David
name: Metje, Jan
name: Ališauskas, Skirmantas
name: Calegari, Francesca
name: Düsterer, Stefan
name: Ehlert, Christopher
name: Feifel, Raimund
name: Niebuhr, Mario
name: Manschwetus, Bastian
name: Kuhlmann, Marion
name: Mazza, Tommaso
name: Robinson, Matthew Scott
name: Squibb, Richard James
name: Trabattoni, Andrea
name: Wallner, Måns
name: Saalfrank, Peter
name: Wolf, Thomas J. A.
name: Gühr, Markus
Publisher: name: Universität Potsdam
Year: 2023
Subjects: subject: 500 Naturwissenschaften und Mathematik

description: The conversion of photon energy into other energetic forms in molecules is accompanied by charge moving on ultrafast timescales. We directly observe the charge motion at a specific site in an electronically excited molecule using time-resolved x-ray photoelectron spectroscopy (TR-XPS). We extend the concept of static chemical shift from conventional XPS by the excited-state chemical shift (ESCS), which is connected to the charge in the framework of a potential model. This allows us to invert TR-XPS spectra to the dynamic charge at a specific atom. We demonstrate the power of TR-XPS by using sulphur 2p-core-electron-emission probing to study the UV-excited dynamics of 2-thiouracil. The method allows us to discover that a major part of the population relaxes to the molecular ground state within 220–250 fs. In addition, a 250-fs oscillation, visible in the kinetic energy of the TR-XPS, reveals a coherent exchange of population among electronic states.
description: Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe; 1301
Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing
Creators: name: Stuckey, Jacob I.
name: Frye, Stephen V.
name: Barnash, Kimberly D.
name: Lamb, Kelsey N.
name: James, Lindsey I.
name: Cholensky, Stephanie H.
name: Norris, Jacqueline L.
name: Kireev, Dmitri B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Efforts to develop strategies for small molecule chemical probe discovery against the readers of the methyl-lysine (Kme) post-translational modification have been met with limited success. Targeted disruption of these protein-protein interactions via peptidomimetic inhibitor optimization is a promising alternative to small molecule hit discovery; however, recognition of identical peptide motifs by multiple Kme reader proteins presents a unique challenge in the development of selective Kme reader chemical probes. These selectivity challenges are exemplified by the Polycomb repressive complex 1 (PRC1) chemical probe, UNC3866, which demonstrates sub-micromolar off-target affinity toward the non-PRC1 chromodomains CDYL2 and CDYL. Moreover, since peptidomimetics are challenging subjects for structure-activity relationship (SAR) studies, traditional optimization of UNC3866 would prove costly and time-consuming. Herein, we report a broadly applicable strategy for the affinity-based, target-class screening of chromodomains via the repurposing of UNC3866 in an efficient, combinatorial peptide library. A first-generation library yielded UNC4991, a UNC3866 analog that exhibits a distinct selectivity profile while maintaining sub-micromolar affinity toward the CDYL chromodomains. Additionally, in vitro pull-down experiments from HeLa nuclear lysates further demonstrate the selectivity and utility of this compound for future elucidation of CDYL protein function.
School-based promotion and prevention interventions for the mental health of children and young people: a scoping literature review of effectiveness, feasibility and acceptability
Creators: name: Ma, Karen
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: children
subject: mental health
subject: mental wellbeing
subject: prevention
subject: promotion
subject: schools
subject: young people

description: According to a survey of the Mental Health of Children and Young People in England 2017, one in eight 5-19 year olds have at least one mental disorder, which saw an overall prevalence of 10% when compared with previous surveys in the series completed in 2004 (Sadler et al., 2018a; Sadler et al., 2018b; Green et al., 2005). The increasing overall prevalence of mental health difficulties amongst children and young people is a concern, as these may lead to serious consequences and adverse outcomes both at an individual and a societal level. From a public health perspective, promotion and prevention interventions for the mental health of children and young people are important strategies to reduce the psychological, social and economic burden of mental disorders, especially given the limitations in treatment and risk of relapses (Ford et al., 2017). In particular, schools are an important setting for interventions, considering how children and young people spend large amount of time at school, how school staff are often the first port of call for them in need of help and advice about their mental health, as well as how mental health difficulties typically begin during the school years (Abdinasir, 2019; Kessler et al., 2015; McGorry et al., 2011). This scoping literature review aims to synthesise evidence for effectiveness, feasibility and acceptability of programmes in the area of mental health promotion and mental health difficulties prevention interventions of children and young people in school settings, as well as identify any research gaps in the existing literature. The review will help researchers identify whether conducting a full systematic review will be relevant or feasible, and help policy makers and practitioners better understand this area of research as they might not have the time or resources to undertake such a review otherwise (Arksey and Malley, 2005).
title: 5.-8. April 2022
Creators: name: Güdemann, Matthias
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022

description: Petri nets are a widely used formalism to describe and analyze critical systems. It is in particular well suited for systems with concurrency like cache coherence protocols, fault-tolerant distributed systems or security critical protocols. The verification approaches for Petri nets are most often based on enumerative approaches which allow for analyzing complex, often temporal, properties. Dataflow languages are widely used in safety critical systems. There are several state-of-the-art model-checkers for these languages. While the properties that can be verified are generally limited to invariants, it is possible to encode some interesting properties of Petri nets as invariants which makes them accessible for powerful analysis methods based on modern SMT and SAT solvers. The SpiNat approach transforms Petri net into synchronous dataflow language models. This allows for using predicate abstraction and the theory of unbounded integers allows to analyze the potentially unbounded markings of Petri nets using model-checking tools for languages like Lustre. The presented approach is orthogonal to enumeration based approaches for Petri net analysis and allows benefiting from any increase in efficiency of industrial strength SMT-based model-checkers like kind2 and Jkind
Nucleon Properties in the Quantized Linear Sigma Model at Finite Temperature and Chemical Potential
Creators: name: Mansour, H. M.
name: Abu-Shady, M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The linear sigma model at finite temperature and chemical potential is systematically studied using the coherent-pair approximation, in which fully taking quantum of fields are included. The expectation value of the chiral Hamiltonian density is minimized and the resulting equations for the nucleon are solved. The qualitative features of the quantized sigma and pion fields are strong sensitive to the change of temperature and baryonic chemical potential and are in agreement with the mean-field approximation calculations. It is noticed that the nucleon mass increases with increasing coherence parameter. In addition, the nucleon mass increases with increasing temperature and the baryonic chemical potential and then it decreases at higher values of the temperature and baryonic chemical potential. The obtained results show that the mean-square radius of the proton and the neutron increase with increasing temperature or the baryonic chemical potential and that the pion-nucleon coupling constant decreases with the temperature or chemical potential. We conclude that the coherent-pair approximation successfully give better description of the nucleon properties at finite temperature and baryonic chemical potential
description: 25 pages, 9 figures, 4 Tables. arXiv admin note: text overlap with arXiv:hep-ph/9809473 by other authors
Expanding the 3- O -Sulfate Proteome—Enhanced Binding of Neuropilin-1 to 3- O -Sulfated Heparan Sulfate Modulates Its Activity
Creators: name: Xu, Yongmei
name: Thacker, Bryan E.
name: Esko, Jeffrey D.
name: Liu, Jian
name: Vander Kooi, Craig W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Binding of proteins to heparan sulfate is driven predominantly by electrostatic interactions between positively charged amino acid residues in the protein and negatively charged sulfate groups located at various positions along the polysaccharide chain. Although many heparin/heparan-sulfate-binding proteins have been described, few exhibit preferential binding for heparan sulfates containing relatively rare 3-O-sulfated glucosamine residues. To expand the "3-O-sulfate proteome," affinity matrices were created from Chinese hamster ovary (CHO) cell heparan sulfate engineered in vitro with and without 3-O-sulfate groups. Fractionation of different animal sera yielded several proteins that bound specifically to columns containing 3-O-sulfated heparan sulfate modified by two members of the heparan sulfate 3-O-sulfotransferase superfamily, Hs3st1 and Hs3st2. Neuropilin-1 was analyzed in detail because it has been implicated in angiogenesis and axon guidance. We show that 3-O-sulfation enhanced the binding of neuropilin-1 to heparan sulfate immobilized on plastic plates and to heparan sulfate present on cultured cells. Chemoenzymatically synthesized 3-O-sulfated heparan sulfate dodecamers protected neuropilin-1 from thermal denaturation and inhibited neuropilin-1-dependent, semaphorin-3a-induced growth cone collapse of neurons derived from murine dorsal root ganglia. The effect of 3-O-sulfation was cell autonomous and specific to Hs3st2 based on collapse assays of neurons derived from Hs3st1- and Hs3st2-deficient mice. Finally, 3-O-sulfated heparan sulfate enhanced the inhibition of endothelial cell sprouting by exogenous heparan sulfate. These findings demonstrate a reliable method to identify members of the 3-O-sulfate proteome and that 3-O-sulfation of heparan sulfate can modulate axonal growth cone collapse and endothelial cell sprouting.
title: 5.-8. April 2022
Creators: name: Lochmann, Fabian
name: Schmerl, Sebastian
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: Cyber-Defense||MITRE ATT&CKTM||Bewertung||Angreifergruppen||Reifegradbestimmung

description: Bei dem hier vorgestellten Cyber-Defense-Maturity-Assessment handelt es sich um eine Methodik zur Erfassung und Bestimmung der Cyber-MITRE ATT&CKTM Framework. Es wird gezeigt, wie sich effizient und praxisorientiert die aktuelle Bedrohungslage für ein Unternehmen inklusive des Branchen-und Geo-Fokus von Abwehr-Fähigkeiten eines Unternehmens. Die Methodik basiert dabei auf dem freien und weltweit anerkannten Angreifer-Gruppen mit Hilfe präventiver sowie auf Erkennung gestützte Security-Controls erfasst und das erforderliche Schutzniveau bestimmen lässt.
title: Examining EMG activity of the elbow flexors and extensors muscles during maximal arm cycling sprints in pronated and supinated forearm positions
Creators: name: Barzegar Ganji, Zahra
Publisher: name: Memorial University of Newfoundland
Year: 2023

description: Sprinting exercise is near maximal or maximal bouts of exercise interspersed with short recovery intervals. Sprinting exercise causes deterioration in performance (e.g., a decline in power output or velocity) due to a decrease in force and the development of neuromuscular fatigue (NMF). Studies have used sprinting exercises to study the interaction between fatigue and performance and have shown that NMF development could differ due to the specific task. For example, NMF development could occur during maximal running and leg cycling exercises at the same workload. This suggests that NMF appears to develop differently depending on the specific action of the muscles involved. To date, only one study has investigated the NMF in arm cycling in pronated versus supinated positions. This study indicated that supinated arm cycling sprints resulted in worse repeated sprint performance and greater NMF than pronated RSE. In sprint-like activities, a common way to quantify the development of NMF is to normalize the EMG of each sprint to the maximum EMG observed during the sprinting or to normalize EMG to the EMG recorded during a maximum voluntary contraction. However, to date, normalization processes for EMG during maximal effort sprinting activities are inconclusive across studies. Moreover, no research has applied the complete recorded EMG signals to interpret muscle activity throughout maximal arm cycling sprint. Therefore, this study aimed to use different EMG normalization methods to elbow flexors and extensors in supinated and pronated positions of arm cycling to examine which method shows better changes in NMF and forearm position. Statistical parametric mapping (SPM) Repeated measure (RM) ANOVA showed significant decreases (p<0.05) in muscle EMG activity of biceps brachii and brachioradialis from sprint 1 to 10 in all normalization methods, as well as a significant (p<0.05) decline in triceps brachii EMG activity in maximum sprint normalization method. Moreover, SPM paired t-tests showed that MVC normalization detected the changes between pronated and supinated positions of biceps brachii and triceps brachii. This study improves our understanding of the best methods of EMG normalization to interpret muscle EMG activity in research and clinical EMG application.
Interdisciplinary high fidelity simulation impact on self-efficacy and knowledge in cardiopulmonary resuscitation training among nursing students: randomized controlled trial
Creators: name: TAKHDAT, Kamal
name: EDDABBAH, Mohamed
name: Hamza, EL
name: Ghassane, EL
name: Saloua, LAMTALI
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Medicine and Health Sciences
subject: Education
subject: Nursing
subject: FOS: Health sciences
subject: Cardiopulmonary resuscitation
subject: High fidelity simulation
subject: Interdisciplinarity
subject: Knowledge
subject: Nursing student
subject: Self-efficacy

description: an experimental study aiming to investigate the impact of High fidelity simulation on Self-efficacy and knowledge in CPR training among undergraduate nursing students.
title: 5.-8. April 2022
Creators: name: Doerner, Dominik
name: Mechler, Jeremias
name: Müller-Quade, Jörn
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: multi-party computation||garbling schemes||universal composability||fortified universal composability

description: Garbling schemes are useful building blocks for enabling secure multi-party computation (MPC), but require considerable computational resources both for the garbler and the evaluator. Thus, they cannot be easily used in a resource-restricted setting, e.g. on mobile devices. To circumvent this problem, server-aided MPC can be used, where circuit garbling and evaluation are performed by one or more servers. However, such a setting introduces additional points of failure: The servers, being accessible over the network, are susceptible to remote hacks. By hacking the servers, an adversary may learn all secrets, even if the parties participating in the MPC are honest. In this work, we investigate how the susceptibility for such remote hacks in the server-aided setting can be reduced. To this end, we modularize the servers performing the computationally intensive tasks. By using data diodes, air-gap switches and other simple remotely unhackable hardware modules, we can isolate individual components during large parts of the protocol execution, making remote hacks impossible at these times. Interestingly, this reduction of the attack surface comes without a loss of efficiency.
Stringy Horizons and UV/IR Mixing
Creators: name: Ben-Israel, Roy
name: Giveon, Amit
name: Itzhaki, Nissan
name: Liram, Lior
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The target-space interpretation of the exact (in $α'$) reflection coefficient for scattering from Euclidean black-hole horizons in classical string theory is studied. For concreteness, we focus on the solvable $SL(2, \mathbb{R})_k/U(1)$ black hole. It is shown that it exhibits a fascinating UV/IR mixing, dramatically modifying the late-time behavior of general relativity. We speculate that this might play an important role in the black-hole information puzzle, as well as in clarifying features related with the non-locality of Little String Theory.
title: 5.-8. April 2022
title: Raising awareness for an invisible problem
titleType: Subtitle
Creators: name: Hennig, Anne
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: web security||vulnerabilities||security notification||security awareness

description: Running a business without having a website is nearly impossible nowadays. Content management systems (CMS) provide features which make it easy for laypersons to create sophisticated websites. But those can pose security risks and provide vulnerabilities for manipulations. With vulnerability notifications, website owners are notified about security risks. The work of this doctoral thesis is divided into two main parts: At first it is necessary to identify common themes with respect to vulnerability notifications and provide more information on how to improve future vulnerability notifications. The second main part is to develop and evaluate suitable awareness materials.
Cohering power of quantum operations
Creators: name: Bu, Kaifeng
name: Kumar, Asutosh
name: Zhang, Lin
name: Wu, Junde
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum coherence is a basic feature of quantum physics. Combined with tensor product structure of state space, it gives rise to the novel concepts such as entanglement and quantum correlations, which play a crucial role in quantum information processing tasks. However, quantum correlations, especially entanglement, are fragile under decoherence. In this context, very few investigations have touched on the production of quantum coherence by quantum operations. In this paper, we study cohering power -- the ability of quantum operations to produce coherence. First, we provide an operational interpretation of cohering power. Then, we decompose a generic quantum operation into three basic operations, namely, unitary, appending and dismissal operations, and show that the cohering power of any quantum operation is upper bounded by the corresponding unitary operation. Furthermore, we compare cohering power and generalized cohering power of quantum operations for different measures of coherence.
description: 11pages, close to the published version
Linguistic and Personological Features of the Doka & Martin Grieving Style Continuum
Creators: name: Geisler, James
name: Dykeman, Cass
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Linguistics
subject: FOS: Languages and literature
subject: Counseling
subject: Social and Behavioral Sciences
subject: Corpus Linguistics
subject: Doka
subject: Grief

description: This study employs a corpus linguistic design of case vignettes of instrumental and intuitive grievers (adaptive grieving styles developed by Dr. Kenneth Doka and Dr. Terry Martin). In this study, the text analysis software, LIWC, will be used to understand the linguistic processes of both instrumental and intuitive grievers.
Regulation of Methyllysine Readers through Phosphorylation
Creators: name: Andrews, Forest H.
name: Krajewski, Krzysztof
name: Gatchalian, Jovylyn
name: Kutateladze, Tatiana G.
name: Strahl, Brian D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Methyllysine post-translational modifications (PTMs) of histones create binding sites for evolutionarily conserved reader domains that link nuclear host proteins and chromatin-modifying complexes to specific genomic regions. In the context of these events, adjacent histone PTMs are capable of altering the binding activity of readers toward their target marks. This provides a mechanism of "combinatorial readout" of PTMs that can enhance, decrease, or eliminate the association of readers with chromatin. In this Perspective, we focus on recent studies describing the impact of dynamic phospho-serine/threonine/tyrosine marks on the interaction of methyllysine readers with histones, summarize mechanistic aspects of the phospho/methyl readout, and highlight the significance of crosstalk between these PTMs. We also demonstrate that in addition to inhibiting binding and serving as a true switch, promoting dissociation of the methyllysine readers from chromatin, the phospho/methyl combination can act together in a cooperative manner--thus adding a new layer of regulatory information that can be encoded in these dual histone PTMs.
title: 5.-8. April 2022
Creators: name: Müller, Robin
name: Ruppert, Julius
name: Will, Katharina
name: Wüsteney, Lukas
name: Heer, Tobias
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: Internet Scanning||Vulnerability Management||Patch Management

description: In view of recent cyberattacks and new regulatory requirements, companies in different industries and countries are forced to implement additional IT security measures. Nevertheless, a large number of services with vulnerable or outdated software can be found on the Internet. In this work, we investigate whether industry-specific differences exist in the maintenance and use of outdated Internet-facing software. For this purpose, we combine results from Internet-wide port scans with product and version information as well as information of companies listed at stock markets in different countries. We show that different industries have more or less up-to-date software for different services like remote access tools, databases, webservers and file servers. With this approach, we discovered surprising amounts of outdated and even unsupported software in use across many industries and countries.
Barynotus (Barynotus) unipunctatus Dufour 1851
Creators: name: Delbol, Marc
name: Perez, Christian
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Barynotus
Barynotus unipunctatus

description: Barynotus (Barynotus) unipunctatus Dufour, 1852
(Figs 41, 53, 62)
 SYNONYME: viridanus Fairmaire, 1857.
 MATÉRIEL EXAMINÉ: France: "Hautes-Pyrénées" sans localité ni date (1♀ RBINS Coll. Bourgoin), "Hautes-Pyrénées", sans localité ni date (1♂ et 2♀♀ RBINS Coll. Roelofs), "Hautes-Pyrénées" sans localité ni date (3♂♂ et 2♀♀ RBINS Coll. A. Fauvel), "Hautes-Pyrénées", sans localité ni date (1♀ RBINS Coll. Gérard-Salme), Cauteret (1♀ RBINS Coll. A. Fauvel), Payolle (1♀ RBINS Coll. A. Fauvel), Gavarnie VII.2001 (1♂ Coll. CPMD), Saint-Lary-Soulan " Col de Portet " VII.1976 (1♂ Coll. CPPC); Haute-Garonne, Luchon sans date (1♀ RBINS Coll. H. Duysson), Luchon sans date (1♀ RBINS Coll. A. Fauvel), Luchon " Port de Venasque " sans date (1♀ Coll. JMLE, leg. H. Dubuysson); Ariège, Couflens " Port d'Aula " 2.200 m VI.2019 (2♀♀ Coll. CPCP).
 DONNÉES COMMUNIQUÉES: France: "Pyrénées" sans localité ni date (1 ex. NMB coll. J. Breit); Hautes-Pyrénées, Beyrède-Jumet " Col de Beyrède " 1.420 m VII.2004 (1 ex. Coll. CPAH), Gavarnie VIII.1964 (1 ex. Coll. CPLS), Barèges 2.200 m VII.1984 (1 ex. Coll. CPDD), Aragnouet "Massif du Néouvielle cirque d'Estaragne" 2.200 m VII.1984 (1 ex. Coll. CPDD); Haute-Garonne, Castillon-de-Larboust " Pic de Céciré " 2.400 m VII.1997 (3 ex. Coll. CPNG).
DISTRIBUTION: Pyrénées françaises et espagnoles.
ETHOLOGIE: Inconnue.
description: Published as part of Delbol, Marc & Perez, Christian, 2020, Barynotus (Barynotus) mainardii mainardii F. Solari, espèce nouvelle pour la faune de France et notes sur le genre Barynotus Germar, 1817 (Curculionidae: Entiminae: Geonemini), pp. 1-31 in Belgian Journal of Entomology 94 on pages 23-24, DOI: 10.5281/zenodo.13711026
SentiWords: Deriving a High Precision and High Coverage Lexicon for Sentiment Analysis
Creators: name: Gatti, Lorenzo
name: Guerini, Marco
name: Turchi, Marco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Deriving prior polarity lexica for sentiment analysis - where positive or negative scores are associated with words out of context - is a challenging task. Usually, a trade-off between precision and coverage is hard to find, and it depends on the methodology used to build the lexicon. Manually annotated lexica provide a high precision but lack in coverage, whereas automatic derivation from pre-existing knowledge guarantees high coverage at the cost of a lower precision. Since the automatic derivation of prior polarities is less time consuming than manual annotation, there has been a great bloom of these approaches, in particular based on the SentiWordNet resource. In this paper, we compare the most frequently used techniques based on SentiWordNet with newer ones and blend them in a learning framework (a so called 'ensemble method'). By taking advantage of manually built prior polarity lexica, our ensemble method is better able to predict the prior value of unseen words and to outperform all the other SentiWordNet approaches. Using this technique we have built SentiWords, a prior polarity lexicon of approximately 155,000 words, that has both a high precision and a high coverage. We finally show that in sentiment analysis tasks, using our lexicon allows us to outperform both the single metrics derived from SentiWordNet and popular manually annotated sentiment lexica.
description: in Affective Computing, IEEE Transactions on (2015)
title: Exploring best practice interventions to protect, promote and support breastfeeding
Creators: name: Blackmore, Alicia Kimberlyn
Publisher: name: Memorial University of Newfoundland
Year: 2022

description: Across Canada (CA) and Newfoundland and Labrador (NL), most women intend to breastfeed; however in actuality rates of EBF tend to decrease drastically. The significant decrease in EBF over time suggests further intervention is needed to provide an environment that promotes breastfeeding. Guided by the Lancet Framework “The components of an enabling environment for breastfeeding—a conceptual model” this dissertation advances the evidence base on the best practice interventions that can enable an environment that supports breastfeeding mothers. The framework outlines three determinants (Structural, Setting, and Individual) that are associated with evidence-based interventions that, if implemented, have a high likelihood of increasing EBF rates. The primary focus of this thesis is to explore the best practice interventions associated with one of three determinants: the Setting. Interventions associated with Setting include those aimed at Health System, Policy and Community. In the first study on the Health System, I evaluated the efficacy of Domperidone, an off-label galactagogue prescribed to mothers by physicians with insufficient human milk production (Chapter Two). In the second study, with a Policy focus, I conducted a data linkage study to examine the differences in health service use (HSU) and associated costs by infant feeding mode, in an infant’s first year of life (Chapter Three). Paired with this study on HSU, my third study explored mothers' perceptions of the costs associated with infant feeding, using a patient-oriented research approach (Chapter Four). In my final study, I evaluate the effectiveness of virtual lactation support for breastfeeding mothers in the Community (Chapter Five). Creating an environment that protects, promotes, and supports breastfeeding involves efforts from Structural, Setting, and Individual levels. The aim of this dissertation is to investigate the best practice interventions that will allow parents to have access to a seamless system of breastfeeding support services in the transition from hospital to the home and community. Policy recommendations will support the additional efforts and funding required for an increase in access to evidence-based breastfeeding support.
Targeted expansion of low-value care lists towards a high-impact short-list, with modelling
Creators: name: Chalmers, Kelsey
name: Elshaug, Adam
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Public Health
subject: Medicine and Health Sciences
subject: Health Services Research

description: The Choosing Wisely campaign has delivered hundreds of low-value care recommendations. However, only several dozen can be reliably measured using routine data (e.g. administrative claims) and so we find ourselves measuring what we can (that is, mapping to inpatient claims variables) rather than what we should. Of those that can be measured some services have high rates of low-value use and are high impact. Others, with moderate or low use are of lower impact from a quality improvement perspective. Expending effort in trying to measure more services at random risks selecting more low-impact items. Rather than expanding to services based solely on what can be measured using administrative data (all may be low impact) a high impact approach is to target services thought to be low-value that are (a) common and/or; (b) expensive; (c) have a high negative safety profile. These are what we should measure. Developing a shortlist of ~5 of these high impact items would have considerably more impact than developing 15, 20 or more new indicators (for services) of low-impact. As our methods may be refined due to input from our panel, we have initially only included a brief summary of stages 2 to 4. These remaining sections will be updated and registered on our OSF project page prior to starting each of the respective stages.
title: 5.-8. April 2022
Creators: name: Hinrichs, Torge
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: Vulnerability Prediction||Vulnerability Detection||Machine Learning||data set generation

description: This paper describes the development of a continuous github repository analysis pipeline with the focus on creating a data set for vulnerability prediction in source code. Currently, used data sets consist only of source code functions or methods without additional meta information. This paper assumes that the surrounding code of vulnerable functions can be beneficial to the detection rate. In order to test this assumption, large data sets are needed that can be created using the proposed pipeline. Although the pipeline requires some improvements, in a first test run 1.5 million repositories could be analyzed and evaluated. The resulting data set will be published in the future.
A comparison of different methods to predict the 2020 United States presidential election: Addendum
Creators: name: Olsson, Henrik
name: de Bruin, Wandi
name: Galesic, Mirta
name: Prelec, Drazen
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Statistics
subject: Public Affairs, Public Policy and Public Administration
subject: Political Science
subject: FOS: Political science
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: In this preregistration we provide predictions for the 2020 United States presidential election derived from respondents’ answers to poll questions. Our aim is to compare different methods to predict elections within a single poll. In this addendum to "A comparison of different methods to predict the 2020 United States presidential election", we provide tables of national-level predictions and state-level predictions for the sixth full wave before the election (Oct 20–Nov 2).
Prison Release: Degrees of Indeterminacy Project
Creators: name: Laskorunsky, Julia
name: Mitchell, Kelly
name: Reitz, Kevin
name: Rhine, Edward
name: Gaes, Gerry
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Criminology and Criminal Justice
subject: Physical Sciences and Mathematics
subject: Criminology
subject: FOS: Law
subject: Legal Studies
subject: Social and Behavioral Sciences
subject: Sociology
subject: FOS: Sociology
subject: parole; prison release; sentencing; discretion; incarceration; NCRP;

description: The purpose of this project is to develop an understanding of the discretionary powers that affect sentence lengths and how they vary across states in order to assist stakeholders in understanding which levers can be targeted to produce reductions in prison populations.
Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation
Creators: name: Liu, Jian
name: Hsieh-Wilson, Linda C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Glycosaminoglycans (GAGs) play critical roles in diverse processes ranging from viral infection to neuroregeneration. Their regiospecific sulfation patterns, which are generated by sulfotransferases, are key structural determinants that underlie their biological activity. Small-molecule modulators of these sulfotransferases could serve as powerful tools for understanding the physiological functions of GAGs, as well as potential therapeutic leads for human diseases. Here, we report the development of the first cell-permeable, small-molecule inhibitor selec-tive for GAG sulfotransferases, which was obtained using a high-throughput screen targeted against Chst15, the sulfotransferase responsible for biosynthesis of chondroitin sulfate-E (CS-E). We demonstrate that the molecule specifically inhibits GAG sulfotransferases in vitro, de-creases CS-E and overall sulfation levels on cell-surface and secreted chondroitin sulfate proteoglycans (CSPGs), and reverses CSPG-mediated inhibition of axonal growth. These studies pave the way toward a new set of pharmacological tools for interrogating GAG sulfation-dependent processes and may represent a novel therapeutic approach for neuroregeneration.
Supplemental materials for preprint: INOVASI PEMBELAJARAN DI ERA COVID-19 BERBASIS BUDAYA LOKAL PADA PENDIDIKAN INDONESIA
Creators: name: JUNAIDI JUNAIDI
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Life Sciences
subject: Education
subject: Social and Behavioral Sciences
subject: Pembelajaran; covid-19; dan budaya lokal;

description: This Paper Contains How Innovation Learning in the Covid-19 Era Is Based on Local Culture in Indonesian Education.
title: 5.-8. April 2022
Creators: name: Demir, Nurullah
name: Theis, Daniel
name: Urban, Tobias
name: Pohlmann, Norbert
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: first-party tracking||cookies||privacy||CNAME cloaking||tracking method

description: Third-party tracking is a common and broadly used technique on the Web. Different defense mechanisms have emerged to counter these practices (e. g. browser vendors that ban all third-party cookies). However, these countermeasures only target third-party trackers and ignore the first party because the narrative is that such monitoring is mostly used to improve the utilized service (e.g. analytical services). In this paper, we present a large-scale measurement study that analyzes tracking performed by the first party but utilized by a third party to circumvent standard tracking preventing techniques. We visit the top 15,000 websites to analyze first-party cookies used to track users and a technique called “DNS CNAME cloaking”, which can be used by a third party to place first-party cookies. Using this data, we show that 76% of sites effectively utilize such tracking techniques. In a long-running analysis, we show that the usage of such cookies increased by more than 50% over 2021.
title: 5.-8. April 2022
title: Untersuchung des Gender-gaps bei Cybersecurity-Publikationen
titleType: Subtitle
Creators: name: Mayer, Nico
name: Wendzel, Steffen
name: Keller, Jörg
Publisher: name: Gesellschaft für Informatik, Bonn
Year: 2022
Subjects: subject: Cybersecurity||IT-Sicherheit||Gender-gap||Bibliometrie||Szientometrie||Zitate

description: Im Bereich der Informatik konnte bereits aufgezeigt werden, dass es eine geringere Anzahl an weiblichen Autoren von wissenschaftlichen Publikationen gibt. Wir untersuchen die Frage, ob es ein ähnliches Verhältnis bei Publikationen im Teilbereich Cybersecurity gibt, ob Frauen seltener zitiert werden als Männer und ob ein Trend in den letzten 10 Jahren erkannt werden kann. Zur Beantwortung der Frage untersuchen wir ausgewählte Journale und Tagungen auf deren Zitierungsanzahl und die Geschlechtsverteilung der Autor:innen. Wir stellen keinen Gender-gap in Form einer Benachteiligung in der Zitierungsanzahl fest, allerdings liegt ein Gender-gap bei der Publikationszahl vor, der jedoch erwartbar ist und zudem in Cybersecurity weniger ausgeprägt ist als in der Informatik als Ganzes.
Automated Krypton Assay in Xenon: Gas Chromatographic System Optimization
Creators: name: Guida, Matteo
Publisher: name: Zenodo
Year: 2023
Subjects: low background radiation detection techniques
noble gas mass spectrometry
direct dark matter detection
max planck institut für kernphysik
XENON dark matter

description: The beta-decaying isotope Kr-85 is one of the main intrinsic background components in liquid xenon dark matter detectors. Via purification techniques, a krypton-in-xenon concentration below 100 ppq (parts per quadrillion) can routinely be achieved. A direct measure of the remaining krypton is crucial for background modelling on the hunt for Physics beyond the Standard Model. In addition, a regular monitor allows to rapidly identify possible detrimental air leaks during detector operations. The rare gas mass spectrometer (RGMS) at Max-Planck Institut für Kernphysik, provides a measurement of the krypton concentration of an extracted xenon gaseous sample taken directly from the experiment. First, krypton is separated from xenon using a cryogenic gas-solid chromatography system. Then, the amount of krypton is quantified using a mass spectrometer. A fully automatic rare gas mass spectrometer (Auto-RGMS) is under construction for the krypton assay of future low-background LXe detectors. Without human effort, the automatic operation is going to enable more frequent krypton monitoring and provide more robust results. The plan is to introduce a novel adsorbent for the chromatography system to increase the xenon sample size and further push down the krypton detection limit. The new solutions show a large enhancement in the separation power at a given temperature and in the linearity of the adsorption isotherms. The progress to select a new adsorbent for Auto-RGMS is discussed.