cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Taraxacum gasparrinii Lojac., Fl. Sicul.
Creators: name: Peruzzi, Lorenzo
name: Galasso, Gabriele
name: Domina, Gianniantonio
name: Bartolucci, Fabrizio
name: Santangelo, Annalisa
name: Alessandrini, Alessandro
name: Astuti, Giovanni
name: D'Antraccoli, Marco
name: Roma-Marzio, Francesco
name: Ardenghi, Nicola M. G.
name: Barberis, Giuseppina
name: Conti, Fabio
name: Bernardo, Liliana
name: Peccenini, Simonetta
name: Stinca, Adriano
name: Wagensommer, Robert P.
name: Bonari, Gianmaria
name: Iamonico, Duilio
name: Iberite, Mauro
name: Viciani, Daniele
name: Guacchio, Emanuele Del
name: Galdo, Gianpietro Giusso Del
name: Lastrucci, Lorenzo
name: Villani, Mariacristina
name: Brunu, Antonello
name: Magrini, Sara
name: Pistarino, Annalaura
name: Brullo, Salvatore
name: Salmeri, Cristina
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Taraxacum
Taraxacum gasparrinii

description: Taraxacum gasparrinii Tineo ex Lojac., Fl. Sicul. 2(1): 201(–202). 1903. [20 September 1903]
 Ind. Loc.:—“ Sicilia locale dell’Etna e del Val Demone. Etna a Nicolosi nell’alta regione boschiva 3 a 7000 p., comune Strobl! Monte di Sorca Strobl! Tin. in Herb. Pan! Vallone degli Zappini, nel Bosco di Centozucchi, Nicolosi, M. del Mozzo Tin! in Herb. Pan. et Guss., Caronie Tin!, Boschi di Cannata e B. di Valdemone Tod! (Tipicissimo) Herb. Pan!” [“Etna Monte di Sorca etc. etc. Nicolosi Monte del Mozzo”, after typification]. SIC
 Type (lectotype designated by Aghababyan et al. 2008: 524):— ITALY. Etna Monte di Sorca etc. etc. Nicolosi Monte del Mozzo, May, Tineo s.n. (PAL11798).
 Note:—According to Arts. 60.1 and 60.8 & 60.9 of the ICN, the spelling of the specific epithet originally published as “ Gasparini ” is to be corrected in “ gasparrinii ”.
 Compiled by:— G. Giusso del Galdo
description: Published as part of Peruzzi, Lorenzo, Galasso, Gabriele, Domina, Gianniantonio, Bartolucci, Fabrizio, Santangelo, Annalisa, Alessandrini, Alessandro, Astuti, Giovanni, D'Antraccoli, Marco, Roma-Marzio, Francesco, Ardenghi, Nicola M. G., Barberis, Giuseppina, Conti, Fabio, Bernardo, Liliana, Peccenini, Simonetta, Stinca, Adriano, Wagensommer, Robert P., Bonari, Gianmaria, Iamonico, Duilio, Iberite, Mauro, Viciani, Daniele, Guacchio, Emanuele Del, Galdo, Gianpietro Giusso Del, Lastrucci, Lorenzo, Villani, Mariacristina, Brunu, Antonello, Magrini, Sara, Pistarino, Annalaura, Brullo, Salvatore & Salmeri, Cristina, 2019, An inventory of the names of native, non-endemic vascular plants described from Italy, their loci classici and types, pp. 1-215 in Phytotaxa 410 (1) on page 164, DOI: 10.11646/phytotaxa.410.1.1, http://zenodo.org/record/13716045
Attenuation of Resting but Not Load-Mediated Protein Synthesis in Prostate Cancer Patients on Androgen Deprivation
Creators: name: Phillips, Stuart M.
name: O'Keefe, Lannie
name: Hanson, Erik D.
name: Hayes, Alan
name: West, Daniel W. D.
name: Violet, John A.
name: Nelson, Andre R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Context: Androgen deprivation therapy (ADT) is a common prostate cancer (PCa) treatment but results in muscular atrophy. Periodic increases in muscle protein synthesis (MPS) that occur after resistance exercise or protein intake may ameliorate this muscle loss, but the impact of these anabolic stimuli during ADT is unclear.

Objective: To determine the acute MPS response to whey protein supplementation with and without resistance exercise during ADT.

Design: Acute response in PCa patients vs age-matched controls (CON).

Setting: Academic laboratory setting.

Participants: PCa patients on ADT (N = 8) and CON (N = 10).

Intervention: A standardized diet was consumed for 2 days prior to performing unilateral knee extension resistance exercise followed by ingestion of 40 g of whey protein.

Main Outcome Measures: Bilateral biopsies and stable isotope infusions were used to determine MPS rates at rest after protein ingestion with and without resistance exercise.

Results: Baseline MPS during ADT was suppressed relative to CON (P = 0.01). Protein consumption stimulated MPS in both groups (approximate twofold increase, both P < 0.001), but to a greater extent in CON (P = 0.003). Protein plus resistance exercise increased MPS (∼3.4-fold increase, both P < 0.001) to a greater extent than did protein alone (P < 0.001), but with no difference between groups (P = 0.380).

Conclusions: ADT reduces basal and protein feeding-induced rises in MPS; however, combined protein ingestion with resistance exercise stimulated MPS to a similar degree as CON. Testosterone appears to play a role in maintaining muscle mass but is not necessary to initiate a robust response in MPS following resistance exercise when combined with protein ingestion.
title: Functional roles of the candidate genes COA4 and POLr3K in Pancreatic Ductal Adenocarcinoma
title: Funktionelle Rolle der Kandidatengene COA4 und POLr3K beim Duktalen Adenokarzinom des Pankreas
titleType: AlternativeTitle
Creators: name: Yang, Yajing
Publisher: name: Philipps-Universität Marburg
Year: 2022
Subjects: 3D cell culture
Medical sciences Medicine
Medizin
cell proliferation
siRNA
PLAU
POLr3K
plasmid
PDAC
RNA-Seq
3D-Zellkultur
Zellmigration
miR-30d-5p
cell migration
COA4
Plasmid
Bauchspeicheldrüse
Zellproliferation

description: Pancreatic cancer is a leading cause of cancer deaths in both men and women, and approximately 90% of all pancreatic malignancies are pancreatic ductal adenocarcinoma (PDAC). Therapeutic efficacy and long-term prognosis of treatment are strongly depended on time of diagnosis and stage of tumor, but overall patient prognosis remains dismal. Thus, it is imperative to further study the underlying biology of PDAC. Previous large-scale expression profiling analyses performed by the group identified, among others, Cytochrome C Oxidase Assembly Factor 4 Homolog (COA4) and RNA Polymerase III Subunit K (POLr3K) as significantly overexpressed among PDAC tissues. My work aimed to detect the molecular function of these two candidate genes in PDAC. RNAi-mediated knockdown approaches against the candidate genes revealed that cell growth inhibition caused by COA4 and POLr3K was due to inhibition of proliferation rather than induction of cell apoptosis. Moreover, knockdown of target genes interfered with anchorage independent growth (both targets) as well as cell migration (only COA4). Expression of the cell cycle related proteins p21 and Cyclin D1 were significantly changed upon siRNA transfection in both cases. Cell cycle analyses by flow cytometry suggested that inhibition of COA4, but not POLr3K, could attenuate cell cycle progression. To further investigate functional effectors of COA4 and POLr3K, RNA-Seq and TaqMan human microRNA array analyses were performed respectively. Gene enrichment analysis and subsequent functional analyses demonstrated that Plasminogen Activator (PLAU) was differentially expressed gene upon COA4 inhibition and was a central mediator of the inhibitory effects of COA4 silencing on cell migratory potential. miR-30d-5p (miR30d) was identified as significantly repressed upon POLr3K inhibition, and rescue experiments using microRNA mimics indicated that miR30d served to regulate cell growth downstream of POLr3K. Tissue microarray (TMA) based immunohistochemistry analyses did not indicate a direct and strong association of COA4 or POLr3K expression with patient survival. Nonetheless, COA4 and POLr3K appeared to be potential novel therapeutic targets in PDAC and may turn out to be clinically useful prognostic markers as well as.
Relaxations of associativity and preassociativity for variadic functions
Creators: name: Couceiro, Miguel
name: Marichal, Jean-Luc
name: Teheux, Bruno
Publisher: name: arXiv
Year: 2015
Subjects: subject: Group Theory (math.GR)
subject: Discrete Mathematics (cs.DM)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 20M05, 20M32, 39B72, 68R99

description: In this paper we consider two properties of variadic functions, namely associativity and preassociativity, that are pertaining to several data and language processing tasks. We propose parameterized relaxations of these properties and provide their descriptions in terms of factorization results. We also give an example where these parameterized notions give rise to natural hierarchies of functions and indicate their potential use in measuring the degrees of associativeness and preassociativeness. We illustrate these results by several examples and constructions and discuss some open problems that lead to further directions of research.
Families of Hitchin systems and N=2 theories
Creators: name: Balasubramanian, Aswin
name: Distler, Jacques
name: Donagi, Ron
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Algebraic Geometry (math.AG)
subject: Representation Theory (math.RT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Motivated by the connection to 4d $\mathcal{N}=2$ theories, we study the global behavior of families of tamely-ramified $SL_N$ Hitchin integrable systems as the underlying curve varies over the Deligne-Mumford moduli space of stable pointed curves. In particular, we describe a flat degeneration of the Hitchin system to a nodal base curve and show that the behaviour of the integrable system at the node is partially encoded in a pair $(O,H)$ where $O$ is a nilpotent orbit and $H$ is a simple Lie subgroup of $F_{O}$, the flavour symmetry group associated to $O$. The family of Hitchin systems is nontrivially-fibered over the Deligne-Mumford moduli space. We prove a non-obvious result that the Hitchin bases fit together to form a vector bundle over the compactified moduli space. For the particular case of $\overline{\mathcal{M}}_{0,4}$, we compute this vector bundle explicitly. Finally, we give a classification of the allowed pairs $(O,H)$ that can arise for any given $N$.
description: 77pp
An Online Tutor for Astronomy: The GEAS Self-Review Library
Creators: name: Vogt, Nicole P.
name: Muise, Amy Smith
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: We introduce an interactive online resource for use by students and college instructors in introductory astronomy courses. The General Education Astronomy Source (GEAS) online tutor guides students developing mastery of core astronomical concepts and mathematical applications of general astronomy material. It contains over 12,000 questions, with linked hints and solutions. Students who master the material quickly can advance through the topics, while under-prepared or hesitant students can focus on questions on a certain topic for as long as needed, with minimal repetition. Students receive individual accounts for study and course instructors are provided with overview tracking information, by time and by topic, for entire cohorts of students. Diagnostic tools support self-evaluation and close collaboration between instructor and student, even for distance learners. An initial usage study shows clear trends in performance which increase with study time, and indicates that distance learners using these materials perform as well as or better than a comparison cohort of on-campus astronomy students. We are actively seeking new collaborators to use this resource in astronomy courses and other educational venues.
description: 15 pages, 9 figures; Vogt, N. P., and A. S. Muise. 2015. An online tutor for general astronomy: The GEAS self-review library. Cogent Education, 2 (1)
MPEC 2023-Q124 : 2023 QW4
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2023 QW4

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
PROMIS Fatigue Item Bank had Clinical Validity across Diverse Chronic Conditions
Creators: name: Christodoulou, Christopher
name: Junghaenel, Doerte U.
name: Lai, Jin-Shei
name: Cella, David
name: Stone, Arthur A.
name: Reeve, Bryce B.
name: Jensen, Sally E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: To evaluate the comparability and responsiveness of PROMIS Fatigue Item Bank across six chronic conditions.
Taraxacum grossum Soest, Veröff. Geobot. Inst. ETH Stiftung Rübel
Creators: name: Peruzzi, Lorenzo
name: Galasso, Gabriele
name: Domina, Gianniantonio
name: Bartolucci, Fabrizio
name: Santangelo, Annalisa
name: Alessandrini, Alessandro
name: Astuti, Giovanni
name: D'Antraccoli, Marco
name: Roma-Marzio, Francesco
name: Ardenghi, Nicola M. G.
name: Barberis, Giuseppina
name: Conti, Fabio
name: Bernardo, Liliana
name: Peccenini, Simonetta
name: Stinca, Adriano
name: Wagensommer, Robert P.
name: Bonari, Gianmaria
name: Iamonico, Duilio
name: Iberite, Mauro
name: Viciani, Daniele
name: Guacchio, Emanuele Del
name: Galdo, Gianpietro Giusso Del
name: Lastrucci, Lorenzo
name: Villani, Mariacristina
name: Brunu, Antonello
name: Magrini, Sara
name: Pistarino, Annalaura
name: Brullo, Salvatore
name: Salmeri, Cristina
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Asterales
Asteraceae
Taraxacum
Taraxacum grossum

description: Taraxacum grossum Soest, Veröff. Geobot. Inst. ETH Stiftung Rübel Zürich 42: 161 (71, 110, fig. 49). 1969.
 Ind. Loc.:—“ Italien, Südtirol, Obervintschgau, Schlinigtal, 1700–1800”. TAA
 Type:— ITALY. Italien, Südtirol, Obervintschgau, Schlinigtal, 1700–1800, 12 July 1956, V. Soest et al. (holotype, Herb. van Soest n. 36849).
 Compiled by:— L. Peruzzi
description: Published as part of Peruzzi, Lorenzo, Galasso, Gabriele, Domina, Gianniantonio, Bartolucci, Fabrizio, Santangelo, Annalisa, Alessandrini, Alessandro, Astuti, Giovanni, D'Antraccoli, Marco, Roma-Marzio, Francesco, Ardenghi, Nicola M. G., Barberis, Giuseppina, Conti, Fabio, Bernardo, Liliana, Peccenini, Simonetta, Stinca, Adriano, Wagensommer, Robert P., Bonari, Gianmaria, Iamonico, Duilio, Iberite, Mauro, Viciani, Daniele, Guacchio, Emanuele Del, Galdo, Gianpietro Giusso Del, Lastrucci, Lorenzo, Villani, Mariacristina, Brunu, Antonello, Magrini, Sara, Pistarino, Annalaura, Brullo, Salvatore & Salmeri, Cristina, 2019, An inventory of the names of native, non-endemic vascular plants described from Italy, their loci classici and types, pp. 1-215 in Phytotaxa 410 (1) on page 164, DOI: 10.11646/phytotaxa.410.1.1, http://zenodo.org/record/13716045
supplementary tables S1 and S2 from The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint
Creators: name: Rathi, Siddhi
name: Polat, Irem
name: Pereira, Gislene
Publisher: name: The Royal Society
Year: 2022
Subjects: Cell Biology
Molecular Biology

description: List of strains and plasmids
Bifurcations in asymptotically autonomous Hamiltonian systems under oscillatory perturbations
Creators: name: Sultanov, Oskar
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 34C23, 34D10, 34D20, 37J65

description: The effect of decaying oscillatory perturbations on autonomous Hamiltonian systems in the plane with a stable equilibrium is investigated. It is assumed that perturbations preserve the equilibrium and satisfy a resonance condition. The behaviour of the perturbed trajectories in the vicinity of the equilibrium is investigated. Depending on the structure of the perturbations, various asymptotic regimes at infinity in time are possible. In particular, a phase locking and a phase drifting can occur in the systems. The paper investigates the bifurcations associated with a change of Lyapunov stability of the equilibrium in both regimes. The proposed stability analysis is based on a combination of the averaging method and the construction of Lyapunov functions.
description: 29 pages, 11 figures
A New Resource for College Distance Education Astronomy Laboratory Exercises
Creators: name: Vogt, Nicole P.
name: Cook, Stephen P.
name: Muise, Amy Smith
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics Education (physics.ed-ph)
subject: FOS: Physical sciences

description: This article introduces a set of distance education astronomy laboratory exercises for use by college students and instructors and discuss first usage results. This General Astronomy Education Source (GEAS) exercise set contains eight two-week projects designed to guide students through both core content and mathematical applications of general astronomy material. Projects are divided between hands-on activities and computer-aided analyses of modern astronomical data. The suite of online resources includes student and instructor guides, laboratory report templates, learning objectives, video tutorials, plotting tools, and web-based applications that allow students to analyze both images and spectra of astronomical objects. A pilot usage study indicates that distance learners using these materials perform as well or better than a comparison cohort of on-campus students. We are actively seeking collaborators to use these resources in astronomy courses and other educational venues.
description: 7 pages, 4 figures
Field theory for zero temperature soft anharmonic spin glasses in a field
Creators: name: Urbani, Pierfrancesco
Publisher: name: arXiv
Year: 2022
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: We introduce a finite dimensional anharmonic soft spin glass in a field and show how it allows the construction a field theory at zero temperature and the corresponding loop expansion. The mean field level of the model coincides with a recently introduced fully connected model, the KHGPS model, and it has a spin glass transition in a field at zero temperature driven by the appearance of pseudogapped non-linear excitations. We analyze the zero temperature limit of the theory and the behavior of the bare masses and couplings on approaching the mean field zero temperature critical point. Focusing on the so called replicon sector of the field theory, we show that the bare mass corresponding to fluctuations in this sector is strictly positive at the transition in a certain region of control parameter space. At the same time the two relevant cubic coupling constants $g_1$ and $g_2$ show a non-analytic behavior in their bare values: approaching the critical point at zero temperature, $g_1\to \infty$ while $g_2\propto T$ with a prefactor diverging at the transition. Along the same lines we also develop the field theory to study the density of states of the model in finite dimension. We show that in the mean field limit the density of states converges to the one of the KHGPS model. However the construction allows a treatment of finite dimensional effects in perturbation theory.
description: 13 pages
supplementary figures S1-S4 from The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint
Creators: name: Rathi, Siddhi
name: Polat, Irem
name: Pereira, Gislene
Publisher: name: The Royal Society
Year: 2022
Subjects: Cell Biology
Molecular Biology

description: supplementary figures
PROMIS measures of pain, fatigue, negative affect, physical function, and social function demonstrated clinical validity across a range of chronic conditions
Creators: name: Weinfurt, Kevin P.
name: Dewalt, Darren A.
name: Czajkowski, Susan
name: Cook, Karon F.
name: Fries, James F.
name: Stone, Arthur A.
name: Schalet, Benjamin D.
name: Jensen, Sally E.
name: Pilkonis, Paul A.
name: Beaumont, Jennifer L.
name: Reeve, Bryce B.
name: Cella, David
name: Amtmann, Dagmar
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: To present an overview of a series of studies in which the clinical validity of the National Institutes of Health’s Patient Reported Outcome Measurement Information System (NIH; PROMIS) measures was evaluated, by domain, across six clinical populations.
Entanglement of assistance in three-qubit systems
Creators: name: Pollock, Klée
name: Wang, Ge
name: Chitambar, Eric
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The entanglement of assistance quantifies the amount of entanglement that can be concentrated among a group of spatially-separated parties using the assistance of some auxiliary system. In this paper we study the entanglement of assistance in the simplest scenario of three qubits. We consider how much entanglement is lost when the helper party becomes uncoupled by local measurement and classical communication. For three-qubit pure states, it is found that lossless decoupling is always possible when entanglement is quantified by the maximum probability of locally generating a Bell state. However, with respect to most other entanglement measures, such as concurrence and entanglement entropy, a lossless decoupling of the helper is possible only for a special family of states that we fully characterize.
A space-time quasi-Trefftz DG method for the wave equation with piecewise-smooth coefficients
Creators: name: Imbert-Gérard, Lise-Marie
name: Moiola, Andrea
name: Stocker, Paul
Publisher: name: arXiv
Year: 2020
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65M60, 65M15, 35L05, 41A10, 41A25

description: Trefftz methods are high-order Galerkin schemes in which all discrete functions are elementwise solution of the PDE to be approximated. They are viable only when the PDE is linear and its coefficients are piecewise constant. We introduce a 'quasi-Trefftz' discontinuous Galerkin method for the discretisation of the acoustic wave equation with piecewise-smooth wavespeed: the discrete functions are elementwise approximate PDE solutions. We show that the new discretisation enjoys the same excellent approximation properties as the classical Trefftz one, and prove stability and high-order convergence of the DG scheme. We introduce polynomial basis functions for the new discrete spaces and describe a simple algorithm to compute them. The technique we propose is inspired by the generalised plane waves previously developed for time-harmonic problems with variable coefficients; it turns out that in the case of the time-domain wave equation under consideration the quasi-Trefftz approach allows for polynomial basis functions.
description: 29 pages, 11 figures, 4 tables
title: The compatible solutes ectoine and 5-hydroxyectoine: Catabolism and regulatory mechanisms
title: Die kompatiblen Solute Ectoin und 5-Hydroxyectoin: Katabolismus und regulatorische Mechanismen
titleType: AlternativeTitle
Creators: name: Hermann, Lucas
Publisher: name: Philipps-Universität Marburg
Year: 2022
Subjects: Transkriptionsregulator
Ectoin
osmotic stress
Genregulation
gene regulation
Enzyme
osmotischer Stress
Life sciences
Biowissenschaften, Biologie
ectoine
transcriptional regulator
kompatible Solute
enzyme
compatible solute

description: To cope with osmotic stress many microorganisms make use of short, osmotically active, organic compounds, the so-called compatible solutes. Examples for especially effective members of this type of molecules are the tetrahydropyrimidines ectoine and 5-hydroxyectoine. Both molecules are produced by a large number of microorganisms, not only to fend-off osmotic stress, but also for example low and high temperature challenges. The biosynthetic pathway used by these organisms to synthesize ectoines has already been studied intensively and the enzymes used therein are characterized quite well, both biochemically as well as structurally. However, synthesis of ectoines is only half the story. Inevitably, ectoines are frequently released from the producer cells in different environmental settings. Especially in highly competitive habitats like the upper ocean layers some bacteria specialized on a niche like this. The model organism used in this work is such a species. It is the marine bacterium Ruegeria pomeroyi DSS-3 which belongs to the Roseobacter-clade. Roseobacter species are heterotrophic Proteobacteria which can live in symbiosis with phytoplankton as well as turning against them in a bacterial warfare fashion to scavenge valuable nutrients. Ectoines can be imported by R. pomeroyi DSS-3 in a high-affinity fashion and be used as energy as well as carbon- and nitrogen-sources. To achieve this, both ectoines rings are degraded by the hydrolase EutD and deacetylated by the deacetylase EutE. The first hydrolysis products α-ADABA (from ectoine) and hydroxy-α-ADABA (from hydroxyectoine) are deacetylated to DABA and hydroxy-DABA which are in additional biochemical reactions transformed to aspartate to fuel the cell’s central metabolism. The role and functioning of the EutDE enzymes which work in a concerted fashion are a central aspect of this work. Both enzymes could be biochemically and structurally characterized, and the architecture of the metabolic pathway could be illuminated. α-ADABA and hydroxy-α-ADABA are not only central to ectoine catabolism, but also to the regulatory mechanisms associated with it. Both molecules serve as inducers of the central regulatory protein of this pathway, the MocR-/GabR-type regulator protein EnuR. In the framework of this dissertation molecular details could be clarified which enable the EnuR repressor molecule to sense both molecules with high affinity to subsequently derepress the genes for the import and catabolism of ectoines.
Flavor hierarchies, flavor anomalies, and Higgs mass from a warped extra dimension
Creators: name: Fuentes-Martin, Javier
name: Isidori, Gino
name: Lizana, Javier M.
name: Selimovic, Nudzeim
name: Stefanek, Ben A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The recent B-meson anomalies are coherently explained at the TeV scale by 4321 gauge models with hierarchical couplings reminiscent of the Standard Model Yukawas. We show that such models arise as the low-energy limit of a complete theory of flavor, based on a warped fifth dimension where each Standard Model family is quasi-localized in a different brane. The Higgs is identified as a pseudo-Nambu-Goldstone boson emerging from the same dynamics responsible for 4321 symmetry breaking. This novel construction unifies quarks and leptons in a flavor non-universal manner, provides a natural description of flavor hierarchies, and addresses the electroweak hierarchy problem.
description: 7 pages, 1 figure
Impact of electron-electron interactions on the thermoelectric efficiency of graphene quantum point contacts
Creators: name: Sánchez-Ramírez, Irián
name: Baba, Yuriko
name: Chico, Leonor
name: Domínguez-Adame, Francisco
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: FOS: Physical sciences

description: Thermoelectric materials open a way to harness dissipated energy and make electronic devices less energy-demanding. Heat-to-electricity conversion requires materials with a strongly suppressed thermal conductivity but still high electronic conduction. This goal is largely achieved with the help of nanostructured materials, even if the bulk counterpart is not highly efficient. In this work, we investigate how thermoelectric efficiency is enhanced by many-body effects in graphene nanoribbons at low temperature. To this end, starting from the Kane-Mele-Hubbard model within a mean-field approximation, we carry out an extensive numerical study of the impact of electron-electron interactions on the thermoelectric efficiency of graphene nanoribbons with armchair or zigzag edges. We consider two different regimes, namely trivial and topological insulator. We find that electron-electron interactions are crucial for the appearance of interference phenomena that give rise to an enhancement of the thermoelectric efficiency of the nanoribbons. Lastly, we also propose an experimental setup that would help to test the validity of our conclusions.
description: 11 pages, 10 figures
Shock-powered radio emission from V5589 Sagittarii (Nova Sgr 2012 1)
Creators: name: Weston, Jennifer H. S.
name: Sokoloski, J. L.
name: Chomiuk, Laura
name: Linford, Justin D.
name: Nelson, Thomas
name: Mukai, Koji
name: Finzell, Tom
name: Mioduszewski, Amy
name: Rupen, Michael P.
name: Walter, Frederick M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Since the Fermi discovery of $γ$-rays from novae, one of the biggest questions in the field has been how novae generate such high-energy emission. Shocks must be a fundamental ingredient. Six months of radio observations of the 2012 nova V5589 Sgr with the VLA and 15 weeks of X-ray observations with Swift/XRT show that the radio emission consisted of: 1) a shock-powered, non-thermal flare; and 2) weak thermal emission from $10^{-5}$ M$_\odot$ of freely expanding, photoionized ejecta. Absorption features in the optical spectrum and the peak optical brightness suggest that V5589 Sgr lies 4 kpc away (3.2-4.6 kpc). The shock-powered flare dominated the radio light curve at low frequencies before day 100. The spectral evolution of the radio flare, its high radio brightness temperature, the presence of unusually hard ($kT_x > 33$ keV) X-rays, and the ratio of radio to X-ray flux near radio maximum all support the conclusions that the flare was shock-powered and non-thermal. Unlike most other novae with strong shock-powered radio emission, V5589 Sgr is not embedded in the wind of a red-giant companion. Based on the similar inclinations and optical line profiles of V5589 Sgr and V959 Mon, we propose that shocks in V5589 Sgr formed from collisions between a slow flow with an equatorial density enhancement and a subsequent faster flow. We speculate that the relatively high speed and low mass of the ejecta led to the unusual radio emission from V5589 Sgr, and perhaps also to the non-detection of $γ$-rays.
description: 12 pages, 6 figures, 3 tables, submitted to MNRAS
Damped perturbations of systems with centre-saddle bifurcation
Creators: name: Sultanov, Oskar
Publisher: name: arXiv
Year: 2020
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 34C23, 34D10, 34D20, 37J65

description: An autonomous system of ordinary differential equations in the plane with a centre-saddle bifurcation is considered. The influence of time damped perturbations with power-law asymptotics is investigated. The particular solutions tending at infinity to the fixed points of the limiting system are considered. The stability of these solutions is analyzed when the bifurcation parameter of the unperturbed system takes critical and non-critical values. Conditions that ensure the persistence of the bifurcation in the perturbed system are described. When the bifurcation is broken, a pair of solutions tending to a degenerate fixed point of the limiting system appears in the critical case. It is shown that, depending on the structure and the parameters of the perturbations, one of these solutions can be stable, metastable or unstable, while the other solution is always unstable.
description: 19 pages, 7 figures
The PROMIS satisfaction with social participation measures demonstrated responsiveness in diverse clinical populations
Creators: name: Dewalt, Darren A.
name: Beaumont, Jennifer L.
name: Pilkonis, Paul A.
name: Hahn, Elizabeth A.
name: Magasi, Susan
name: Cella, David
name: Garcia, Sofia F.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: To conduct a longitudinal evaluation of PROMIS® Social Function measures (Satisfaction with Participation in Social Roles, and Satisfaction with Participation in Discretionary Social Activities) in English-speaking people with chronic health conditions.
Resonances in asymptotically autonomous systems with a decaying chirped-frequency excitation
Creators: name: Sultanov, Oskar
Publisher: name: arXiv
Year: 2021
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 34D10, 34D20, 34C15, 37J65

description: The influence of oscillatory perturbations on autonomous strongly nonlinear systems in the plane is investigated. It is assumed that the intensity of perturbations decays with time, and their frequency increases according to a power law. The long-term behaviour of perturbed trajectories is discussed. It is shown that, depending on the structure and the parameters of perturbations, there are at least two different asymptotic regimes: a phase locking and a phase drifting. In the case of phase locking, resonant solutions with an unlimitedly growing energy occur. The stability and asymptotics at infinity of such solutions are investigated. The proposed analysis is based on a combination of the averaging technique and the method of Lyapunov functions.
description: 22 pages, 4 figures
supplementary tables S1 and S2 from The budding yeast GSK-3 homolog Mck1 is an essential component of the spindle position checkpoint
Creators: name: Rathi, Siddhi
name: Polat, Irem
name: Pereira, Gislene
Publisher: name: The Royal Society
Year: 2022
Subjects: Cell Biology
Molecular Biology

description: List of strains and plasmids
The number of primary events per variable affects estimation of the subdistribution hazard competing risks model
Creators: name: Fine, Jason P.
name: Allignol, Arthur
name: Austin, Peter C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: AbstractObjectivesTo examine the effect of the number of events per variable (EPV) on the accuracy of estimated regression coefficients, standard errors, empirical coverage rates of estimated confidence intervals, and empirical estimates of statistical power when using the Fine–Gray subdistribution hazard regression model to assess the effect of covariates on the incidence of events that occur over time in the presence of competing risks.Study Design and SettingMonte Carlo simulations were used. We considered two different definitions of the number of EPV. One included events of any type that occurred (both primary events and competing events), whereas the other included only the number of primary events that occurred.ResultsThe definition of EPV that included only the number of primary events was preferable to the alternative definition, as the number of competing events had minimal impact on estimation. In general, 40–50 EPV were necessary to ensure accurate estimation of regression coefficients and associated quantities. However, if all of the covariates are continuous or are binary with moderate prevalence, then 10 EPV are sufficient to ensure accurate estimation.ConclusionAnalysts must base the number of EPV on the number of primary events that occurred.
Unveiling the Enhancement of Spontaneous Emission at Exceptional Points
Creators: name: Ferrier, Lydie
name: Bouteyre, Paul
name: Pick, Adi
name: Cueff, Sébastien
name: Dang, Nguyen Ha My
name: Diederichs, Carole
name: Belarouci, Ali
name: Benyattou, Taha
name: Zhao, Jiaxin
name: Su, Rui
name: Xing, Jun
name: Xiong, Qihua
name: Nguyen, Hai-Son
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Exceptional points (EPs), singularities of non-Hermitian physics where complex spectral resonances degenerate, are one of the most exotic features of nonequilibrium open systems with unique properties. For instance, the emission rate of quantum emitters placed near resonators with EPs is enhanced (compared to the free-space emission rate) by a factor that scales quadratically with the resonance quality factor. Here, we verify the theory of spontaneous emission at EPs by measuring photoluminescence from photonic-crystal slabs that are embedded with a high-quantum-yield active material. While our experimental results verify the theoretically predicted enhancement, it also highlights the practical limitations on the enhancement due to material loss. Our designed structures can be used in applications that require enhanced and controlled emission, such as quantum sensing and imaging.
Factors affecting stresses in cortical bone around miniscrew implants
Creators: name: Duaibis, Ramzi
name: Kusnoto, Budi
name: Natarajan, Raghu
name: Zhao, Linping
name: Evans, Carla
Publisher: name: University of Illinois at Chicago
Year: 2023
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3203
subject: Dentistry
subject: FOS: Clinical medicine

description: OBJECTIVE: To evaluate various types of stress in cortical bone around miniscrew implants using finite element analysis. MATERIALS AND METHODS: Twenty-six three-dimensional assemblies of miniscrew models placed in alveolar bone blocks were constructed using Abaqus (Dassault Systèmes Simulia Corp, Providence, RI), a commercial finite element analysis software package. The model variables included implant design factors and bone-related factors. All miniscrew implants were loaded in the mesial direction with a linear force equal to 2 N. Peak von Mises and principal stress values in cortical bone were compared between the different models for each factor. RESULTS: The results demonstrated that some factors affected the stresses in bone (implant diameter, implant head length, thread size, and elastic modulus of cancellous bone), while other factors did not (thread shape, thread pitch, and cortical bone thickness). CONCLUSIONS: Miniscrew implant diameter, head length, and thread size as well as the elastic modulus of cancellous bone affect the stresses in cortical bone layer surrounding the miniscrew implant and may therefore affect its stability.
STRUCTURAL PROPERTIES AND FUNCTIONAL TAILORING OF REFINED OR UNREFINED PLANT-BASED MATERIALS OBTAINED BY EXTRACTION OR BIO-TRANSFORMATION OF AGRO-FOOD WASTES
Creators: name: ROCCHI, ELISA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: L?impiego delle risorse in maniera efficiente � una tematica di interesse globale, sia da un punto di vista ambientale che economico. La produzione di grandi quantit� di residui agro-alimentari � una delle principali cause di inefficienza a livello di produzione industriale. Questi materiali hanno ancora un elevato contenuto di materiale organico, ricco in composti naturali preziosi e peculiari strutture che, una volta identificati, possono essere estratti e valorizzati per via fisica, chimica o biotecnologica. Per queste ragioni, negli ultimi anni si osserva un crescente interesse sia scientifico che industriale per il recupero e la valorizzazione di materiali di scarto. In questo contesto, questo progetto di dottorato si propone di investigare le potenzialit� di ingredienti derivati da residui agro-alimentari per la formulazione alimentare. La caratterizzazione strutturale e funzionale delle matrici considerate ha seguito un approccio tipico della scienza dei materiali, basato sull?analisi quantitativa mediante modelli matematici per promuovere e controllare specifici fenomeni e modificazioni in grado di migliorare le propriet� funzionali del sistema formulato. Nella presente tesi di dottorato sono stati considerati quattro diversi materiali. La cellulosa nano cristallina � stata caratterizzata da un punto di vista reo-ottico per meglio comprendere quale sia relazione esistente tra l?organizzazione nematica e lo stato cineticamente arrestato. Gli estratti di parete vegetale (CWM) sono stati studiati nell?ottica di un loro impiego come sistemi per il trasporto di composti bioattivi, agendo soprattutto sull?organizzazione della matrice polimerica di parete con lo scopo di poter meglio controllare il rilascio dei composti di interesse. Le frazioni di farina di semi di canapa sono state valutate in termini di capacit� texturizzante e strutturante. La cellulosa batterica si � dimostrata invece un eccellente supporto per la ritenzione di molecole volatili.
Asymptotic symmetries and soft charges of fractons
Creators: name: Pérez, Alfredo
name: Prohazka, Stefan
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The asymptotic structure of gauge theories describing fracton interactions is analyzed. Two sets of asymptotic conditions are proposed. Both encompass all known solutions, lead to finite charges and resolve the problem of the divergent energy coming from the monopole contribution. While the first set leads to the expected fracton symmetry algebra, including a dipole charge, the second set provides a soft infinite-dimensional extension of it. These soft charges provide evidence of a rich infrared structure for fracton-like theories and provide one corner of a possible fracton infrared triangle.
description: 8 pages, v2: Various minor updates, matches published version
Inaccessibility of traversable wormholes
Creators: name: Terno, Daniel R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Wormhole solutions to the equations of general relativity have some spectacular local and global properties. As these unusual features are not explicitly forbidden by known physics, wormholes are considered in various astrophysical and cosmological scenarios. The paradigmatic traversable wormhole models are described by static spherically-symmetric Ellis--Morris--Thorne and Simpson--Visser metrics. We show that no dynamical solution of the semiclassical Einstein equations can have these metrics as their static limit. On the other hand, possible static limits of the dynamical solutions are not traversable. Moreover, they lead to violation of a quantum energy inequality that bounds violations of the null energy condition by quantum fields. This conclusion does not depend on specific properties of fields that may be proposed for wormhole construction. As a result, spherically-symmetric wormholes cannot exist in semiclassical gravity.
description: 6 pages. Comments welcome!
The BEHOMO project: $Λ$LTB $N$-body simulations
Creators: name: Marra, V.
name: Castro, T.
name: Camarena, D.
name: Borgani, S.
name: Ragagnin, A.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Our Universe may feature large-scale inhomogeneities and anisotropies which cannot be explained by the standard model of cosmology, that is, the homogeneous and isotropic FLRW metric, on which the $Λ$CDM model is built, may not describe accurately observations. Currently, there is not a satisfactory understanding of the evolution of the large-scale structure on an inhomogeneous background. We start the cosmology beyond homogeneity and isotropy (BEHOMO) project and study the inhomogeneous $Λ$LTB model with the methods of numerical cosmology. Understanding the evolution of the large-scale structure is a necessary step to constrain inhomogeneous models with present and future observables and place the standard model on more solid grounds. We perform Newtonian $N$-body simulations, whose accuracy in describing the background evolution is checked against the general relativistic solution. The large-scale structure of the corresponding $Λ$CDM simulation is also validated. We obtain the first set of simulations of the $Λ$LTB model ever produced. The data products consist of 11 snapshots between redshift 0 and 3.7 for each of the 68 simulations that have been performed, together with halo catalogs and lens planes relative to 21 snapshots, between redshift 0 and 4.2, for a total of approximately 180 TB of data. We plan to study the growth of perturbations at the linear and nonlinear level, gravitational lensing, cluster abundances and proprieties. Data can be obtained upon request. Further information is available at valerio-marra.github.io/BEHOMO-project .
description: 17 pages, 6 figures (excluding appendices). Accepted for publication in A&A. For informations on the BEHOMO project please see https://valerio-marra.github.io/BEHOMO-project
supplementary figures S1-S4 from The budding yeast GSK-3 homolog Mck1 is an essential component of the spindle position checkpoint
Creators: name: Rathi, Siddhi
name: Polat, Irem
name: Pereira, Gislene
Publisher: name: The Royal Society
Year: 2022
Subjects: Cell Biology
Molecular Biology

description: supplementary figures
A continuous space model of new economic geography with a quasi-linear log utility function
Creators: name: Ohtake, Kensuke
Publisher: name: arXiv
Year: 2021
Subjects: subject: Theoretical Economics (econ.TH)
subject: Dynamical Systems (math.DS)
subject: FOS: Economics and business
subject: FOS: Mathematics

description: We consider the extension of a tractable NEG model with a quasi-linear log utility to continuous space, and investigate the behavior of its solution mathematically. The model is a system of nonlinear integral and differential equations describing the market equilibrium and the time evolution of the spatial distribution of population density. A unique global solution is constructed and a homogeneous stationary solution with evenly distributed population is shown to be unstable. Furthermore, it is shown numerically that the destabilized homogeneous stationary solution eventually forms spiky spatial distributions. The number of the spikes decreases as the preference for variety increases or the transport cost decreases.
description: 27 pages, 24 figures
Rydberg Quantum Wires for Maximum Independent Set Problems with Nonplanar and High-Degree Graphs
Creators: name: Kim, Minhyuk
name: Kim, Kangheun
name: Hwang, Jaeyong
name: Moon, Eun-Gook
name: Ahn, Jaewook
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: One prominent application of near-term quantum computing devices is to solve combinatorial optimization such as non-deterministic polynomial-time hard (NP-hard) problems. Here we present experiments with Rydberg atoms to solve one of the NP-hard problems, the maximum independent set (MIS) of graphs. We introduce the Rydberg quantum wire scheme with auxiliary atoms to engineer long-ranged networks of qubit atoms. Three-dimensional (3D) Rydberg-atom arrays are constructed, overcoming the intrinsic limitations of two-dimensional arrays. We demonstrate Kuratowski subgraphs and a six-degree graph, which are the essentials of non-planar and high-degree graphs. Their MIS solutions are obtained by realizing a programmable quantum simulator with the quantum-wired 3D arrays. Our construction provides a way to engineer many-body entanglement, taking a step toward quantum advantages in combinatorial optimization.
description: 8 pages, 4 figures