cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Precipitated Withdrawal Induced by Prehospital Naloxone Administration
Creators: name: Vandergrift, Lindsey A.
name: Rice, Amber D.
name: Primeau, Keith
name: Gaither, Joshua B.
name: Munn, Rachel D.
name: Hannan, Philipp L.
name: Knotts, Mary C.
name: Hollen, Adrienne
name: Stevens, Brian
name: Lara, Justin
name: Glenn, Melody
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Mental Health
subject: Hematology

description: Buprenorphine is becoming a key component of prehospital management of opioid use disorder. It is unclear how many prehospital patients might be eligible for buprenorphine induction, as traditional induction requires that patients first have some degree of opioid withdrawal. The primary aim of this study was to quantify how many patients developed precipitated withdrawal after receiving prehospital naloxone for suspected overdose, as they could be candidates for prehospital buprenorphine. The secondary objective was to identify associated factors contributing to precipitated withdrawal, including dose of naloxone administered, and identify rate of subsequent transport. A retrospective cohort study reviewing electronic patient care reports (ePCRs) from March 2019 to April 2023 in a single Emergency Medical Services (EMS) system was performed. Cases were included if naloxone was administered during the prehospital interval and excluded if the patient was in cardiac arrest upon arrival and died on scene. Precipitated opioid withdrawal was defined using reliably available ePCR data points measured by the Clinical Opiate Withdrawal Scale: administration of an antiemetic or sedative, persistent tachycardia, or new tachycardia after naloxone. Descriptive statistics were calculated to quantify the incidence of precipitated withdrawal. Risk ratios were calculated to identify variables associated with outcomes of interest. A subgroup analysis was performed examining patients explicitly diagnosed with an overdose by EMS. During the study period, 4561 individuals were given naloxone, and 2124 (46.2%) met our proxy criteria for precipitated withdrawal. Patients who received multiple doses of naloxone were more likely to meet our precipitated withdrawal definition versus those who received a single dose (RR 1.2, 95% CI 1.12–1.28). Patients who experienced precipitated withdrawal were more likely to accept transportation than those who did not experience withdrawal (RR 1.08 95% CI 1.04–1.12). Persistent tachycardia (80.3%) was the most common criterion met for our definition of precipitated withdrawal. Almost half of patients who received a dose of prehospital naloxone for suspected overdose met our proxy criteria for precipitated withdrawal. Patients who met our precipitated withdrawal definition were more likely to have received greater doses of naloxone and were more likely to accept transport to an emergency department.
Destiny and the Law: The California Land Act of 1850
Creators: name: Rieger, Maximilian Joseph
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Historical studies not elsewhere classified

description: The California Land Act sought to remake landholding in early California. Though bound by promises to uphold existing ownership in the treaty of Guadeloupe Hidalgo, the United States attempted to use the law to fundamentally change who held land in California and the exploitation of its resources. Analysis of archival materials demonstrates that the California Land Act intended to transform California from a ranching-based economy dominated by large landholders of Spanish descent into an agrarian economy dependent on small scale farming modeled on the traditional land use of the eastern United States. This intrinsic policy characterized the legislative formation of the act, and years later influenced North American settlement policies of formerly French and Imperial Mexican territories. As such, this study focuses on a little understood agent of change: the administrative law. A careful examination of the crafting and implementation of the California Land Act reveals that land law legislation and its extra-judicial commission, alongside other more traditional markers of American occupation, occupied a prominent place in the continued colonization California.
Serological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011
Creators: name: Balabanova, Yanina
name: Klar, Stefanie
name: Deleré, Yvonne
name: Wilking, Hendrik
name: Faber, Mirko
name: Lassen, Sofie Gillesberg
name: Gilsdorf, Andreas
name: Dupke, Susann
name: Nitschke, Martin
name: Sayk, Friedhelm
name: Grunow, Roland
name: Krause, Gérard
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2013
Subjects: subject: Humans
subject: Female
subject: Male
subject: Reproducibility of Results
subject: Aged
subject: Germany/epidemiology
subject: Middle Aged
subject: Disease Outbreaks
subject: Escherichia coli Infections/diagnosis
subject: Escherichia coli Infections/epidemiology
subject: Asymptomatic Infections/epidemiology
subject: Escherichia coli/classification
subject: Serotyping/methods
subject: Shiga-Toxigenic Escherichia coli/classification
subject: 610 Medizin

description: Introduction: The largest known outbreak caused by a rare hybrid strain of Shiga toxin-producing E.coli (STEC) and enteroaggregative E. coli (EAEC) (E.coli O104:H4) of serotype O104:H4 occurred in Germany in 2011. Fenugreek sprouts acted as a transmission vehicle and were widely consumed in the outbreak area at the time of the epidemic. In total 3,842 people developed a clinical illness caused by this strain; however the rates of asymptomatic infections remain unclear. We aimed to develop a serological assay for detection of E.coli O104 LPS specific antibodies and to establish the post-outbreak levels of seropositivity among people with documented exposure to contaminated sprouts. Results and Discussion: Developed serological assays (ELISA with 84% sensitivity, 63% specificity and Western Blot with 100% sensitivity, 82.5% specificity) identified 33% (16/49) level of asymptomatic infection. Relatively small sample size and a significant time- lapse between the onset of symptoms and serum samples collection (appr. 8 weeks) might explain the assay variability. No association was found between clinical or demographic characteristics and assay positivity. Larger studies are needed to understand the complexity of human immune response and factors influencing development of clinical symptoms. Development of intra-outbreak research plans will substantially aid the conduct of more thorough scientific investigation during an outbreak period.
Additional file 1 of Barriers and facilitators of older adults for professional mental health help-seeking: a systematic review
Creators: name: Elshaikh, Usra
name: Sheik, Rayan
name: Saeed, Raghad Khaled Mohammad
name: Chivese, Tawanda
name: Alsayed Hassan, Diana
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 1. Preferred Reporting Items for Systematic Reviews and Meta-Analyses Checklist.
Find and treat or find and lose? Tuberculosis treatment outcomes among screened newly arrived asylum seekers in Germany 2002 to 2014
Creators: name: Kuehne, Anna
name: Hauer, Barbara
name: Brodhun, Bonita
name: Haas, Walter
name: Fiebig, Lena
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2018
Subjects: subject: 610 Medizin

description: Background: Germany has a low tuberculosis (TB) incidence. A relevant and increasing proportion of TB cases is diagnosed among asylum seekers upon screening. Aim: We aimed to assess whether cases identified by screening asylum seekers had equally successful and completely reported treatment outcomes as cases diagnosed by passive case finding and contact tracing in the general population. Methods: We analysed characteristics and treatment outcomes of pulmonary TB cases notified in Germany between 2002 and 2014, stratified by mode of case finding. We performed three multivariable analyses with different dependent variables: Model A: successful vs all other outcomes, Model B: successful vs documented non-successful clinical outcome and Model C: known outcome vs lost to follow-up. Results: TB treatment success was highest among cases identified by contact tracing (87%; 3,139/3,591), followed by passive case finding (74%; 28,804/39,019) and by screening asylum seekers (60%; 884/1,474). Cases identified by screening asylum seekers had 2.4 times higher odds of not having a successful treatment outcome as opposed to all other outcomes (A), 1.4 times higher odds of not having a successful treatment outcome as opposed to known non-successful outcomes (B) and 2.3 times higher odds of loss to follow-up (C) than cases identified by passive case finding. Conclusion: Screened asylum seekers had poorer treatment outcomes and were more often lost to follow-up. Linking patients to treatment facilities and investigating potential barriers to treatment completion are needed to secure screening benefits for asylum seekers and communities.
Alexandromys shantaricus Ognev 1929
Creators: name: Sheremetyeva, I. N.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Rodentia
Cricetidae
Alexandromys
Alexandromys shantaricus

description: 10. Alexandromys shantaricus Ognev, 1929 — поΛёвка Громова
 Синонимы: Microtus maximowiczii gromovi Vorontsov, 1988: Воронцов и Αр. 1988; Мейер и Αр. 1996. — Microtus oeconomus shantaricus Ognev 1929: Огнев 1929; Костенко, АΛенова 1989. — Microtus gromovi: Sheremetyeva et al. 2009.
 ПоΛёвка Громова Αо 2009 гоΑа вхоΑиΛа в состав поΛёвки Максимовича в качестве поΑвиΑа Microtus (= Alexandromys) m. gromovi Vorontsov, 1988. ТоΛько компΛекс морфоΛогического и генетического иссΛеΑования позвоΛиΛ повысить таксономический ранг Αо виΑового Microtus gromovi (Sheremetyeva et al. 2009). В резуΛьтате посΛеΑующих таксономических работ, согΛасно правиΛу приоритета, виΑ поΛучиΛ название A. shantaricus (= A. gromovi (Dokuchaev 2014). A. shantaricus Αостаточно реΑко упоминается в зооΛогических работах. В настоящее время ареаΛ этого виΑа все еще уточняется, оΑнако все известные нахоΑки приурочены к высокогорным районам Станового хребта, хребта ΔжугΑжур и МайманΑжинского хребта и к прибрежным районам Охотского моря. К настоящему времени наберется не боΛее восьми нахоΑок поΛёвки Громова из сΛеΑующих мест: 1) озеро БоΛьшое Токо (47 ° 05΄N, 112 ° 55 ° E) на границе Хабаровского края и Якутии (Воронцов и Αр. 1988), эту нахоΑку можно считать как место первоописания виΑа; 2) устье реки НеΛьканка (56 ° 44΄N, 138 ° 11΄E) Хабаровский край (Шреметьева и Αр. 2010; Sheremetyeva et al. 2009); 3) окрестностей пос. Аян Хабаровского края (56 ° 27΄N, 138 ° 9΄E) (Шреметьева и Αр. 2010); 4) окрестностей пос. Аян Хабаровского края (56 ° 26΄N, 138 ° 10΄E); 5) р. УΑа, 25 км выше п. Чумикана(54 ° 36΄N, 135 ° 0΄E.) Тугуро-Чумиканский р-н Хабаровского края (Αисовский, ОбоΛенская 2011); 6) верховье р. Ямы (60 ° 39΄N, 152 ° 12΄E), МайманΑжинский хр. КоΛымское нагорье, МагаΑанская обΛасть края (Αисовский, ОбоΛенская 2011); 7) остров БоΛьшой Шантар (Δокучаев, ОΛейников 2014; Dokuchaeva, Sheremetyeva 2018); 8) Токинский становик, север Зейского района Амурской обΛасти, (55 ° 41΄N, 129 ° 58΄E).
 Помимо описанных выше 10 виΑов роΑа Microtus на территории ЗабайкаΛья и ΔаΛьнего Востока России можно встретить 4 виΑа серых поΛёвок, относящихся к роΑу Lasiopodomys. В ЗабайкаΛье можно встретить всех преΑставитеΛей роΑа Lasiopodomys, тогΑа как на территории ΔВ России встречается тоΛько узкочерепная поΛёвка.
description: Published as part of Sheremetyeva, I. N., 2023, Species composition and distribution of gray voles in Transbaikalia and the Russian Far East, pp. 724-743 in Amurian Zoological Journal XV (4) on pages 731-732, DOI: 10.33910/2686-9519-2023-15-4-724-743, http://zenodo.org/record/11362261
Lessons Learned from the Implementation of the Wake County, North Carolina EMS Medication for Opioid Use Disorder Program
Creators: name: Godfrey, Andrew W.
name: Coles, Vicki L.
name: Lyons, Michael D.
name: Williams, Jefferson G.
name: Studnek, Jonathan R.
name: Cain, Kristin M.
name: Smith, Brandon
name: Powell, Benjamin W.
name: Newsam, Gabrielle D.
name: Cabañas, José G.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Ecology
subject: Science Policy
subject: Cancer
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Buprenorphine has recently emerged as a prehospital treatment for opioid use disorder. Limited data exist regarding the implementation of prehospital buprenorphine programs. Our objective was to describe the development, deployment, lessons learned, and ongoing evolution of the Wake County EMS buprenorphine program using data from the first year following implementation. We developed a protocol to provide buprenorphine in the prehospital setting to patients who 1) suffered an opioid overdose with reversal using naloxone, or 2) experienced withdrawal symptoms at least 72 hours after last opioid use. Measures included encounters with screening for buprenorphine induction, successful inductions with buprenorphine, successful follow up with outpatient treatment, and successful continued outpatient treatment. For the period 7/5/2023–7/4/2024, we report descriptive statistics. We identified 1,378 encounters for adult patients who received naloxone, of which 953 had documentation of opioid overdose as the primary impression. During the same timeframe, 342 encounters included screening for prehospital buprenorphine induction. Of encounters with screened patients, 66 (19.3%) encounters were eligible for buprenorphine induction and of these, 61 encounters (92.4%) resulted in buprenorphine induction. Of encounters with induction, 29 (47.5%) resulted in successful follow up with our outpatient provider, and 7 (11.4%) remained in treatment at the end of the review period. Our prehospital buprenorphine induction program successfully inducted eligible patients and connected them with follow up. Almost half of inducted patients were able to follow up with our outpatient provider. One in ten patients who received buprenorphine from EMS remained in treatment. There exists an opportunity for EMS to screen more patients for buprenorphine induction as only one in four patients who received naloxone were screened for buprenorphine induction. Lessons learned include the need for recurrent EMS clinician education regarding buprenorphine screening, the need for a “buprenorphine champion” to follow up with inducted patients and addressing early administrative and technological barriers to ensure data exchange.
Privacy-Enhancing Techniques for Data Analytics
Creators: name: Rao, Fang-Yu
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: System and network security
Cryptography

description: Organizations today collect and aggregate huge amounts of data from individuals under various scenarios and for different purposes. Such aggregation of individuals’ data when combined with techniques of data analytics allows organizations to make informed decisions and predictions. But in many situations, different portions of the data associated with individuals are collected and curated by different organizations. To derive more accurate conclusions and predictions, those organization may want to conduct the analysis based on their joint data, which cannot be simply accomplished by each organization exchanging its own data with other organizations due to the sensitive nature of data. Developing approaches for collaborative privacy-preserving data analytics, however, is a nontrivial task. At least two major challenges have to be addressed. The first challenge is that the security of the data possessed by each organization should always be properly protected during and after the collaborative analysis process, whereas the second challenge is the high computational complexity usually accompanied by cryptographic primitives used to build such privacy-preserving protocols.
 In this dissertation, based on widely adopted primitives in cryptography, we address the aforementioned challenges by developing techniques for data analytics that not only allow multiple mutually distrustful parties to perform data analysis on their joint data in a privacy-preserving manner, but also reduce the time required to complete the analysis. More specifically, using three common data analytics tasks as concrete examples, we show how to construct the respective privacy-preserving protocols under two different scenarios: (1) the protocols are executed by a collaborative process only involving the participating parties; (2) the protocols are outsourced to some service providers in the cloud. Two types of optimization for improving the efficiency of those protocols are also investigated. The first type allows each participating party access to a statistically controlled leakage so as to reduce the amount of required computation, while the second type utilizes the parallelism that could be incorporated into the task and pushes some computation to the offline phase to reduce the time needed for each participating party without any additional leakage. Extensive experiments are also conducted on real-world datasets to demonstrate the effectiveness of our proposed techniques.
Linguistic Landscape in Educational Spaces
Creators: name: Bernardo-Hinesley, Sheryl
Publisher: name: Humanities Commons
Year: 2020
Subjects: subject: Education, Bilingual

description: Educational institutions, whether privately owned or state funded, are a meeting place for students coming from diverse linguistic and cultural backgrounds. Educational institutions as learning environments and spaces not only play a fundamental role in the development of an individual, but also perpetuate various ideologies related to languages, politics, cultures, and society among others. In relation to language ideology, linguistic landscape is a novel field which allows sociolinguists to analyze how spaces are constituted through the language(s) employed in public signage as signs enable a dynamic process in which the language(s) used in these signs and those who pass by said signs influence each other to shape the landscape of their community. It enables the identification of the relative power and vitality of the language(s) in a particular community that may or may not appear in public signage. Language(s) displayed in public spaces can also be interpreted as a reflection of the ideological conflicts within a community. Respectively, there is a growing interest towards the study of the linguistic landscape in educational spaces, also known as schoolscape. School, a central civic institution, represents a deliberate and planned environment where learners are subjected to powerful messages about language(s) from local and national authorities. Accordingly, by reviewing past studies, this paper proposes to initiate discussion and investigation of the practices and the language(s) utilized in signs within educational spaces in the United States as institutions can perpetuate language ideologies, which can either foster or hinder bilingual education.
Evaluation of the safety profile of amivantamab based on real-world evidence: a call to vigilance
Creators: name: Liao, Zuyue
name: Luo, Cheng
name: Huang, Yinghua
name: Jiang, Zhongcai
name: Wei, Hongqun
name: Wang, Yu
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Amivantamab has been approved for EGFR exon 20 insertion-mutated non-small-cell lung cancer. The aim of this study was to perform an in-depth analysis of its safety profile. Safety reports were collected from the database of the Food and Drug Administration Adverse Event Reporting System from April 2021 to September 2023, and the reporting odds ratio (ROR) method was used to detect potential safety signals. Mobocertinib, an agent with similar properties to amivantamab, served as a control for comparison. A total of 88 safety signals were detected, most of which were novel. In comparison with mobocertinib, amivantamab appeared to cause more injury, poisoning, and procedural complications (ROR = 15.54, 95% CI 10.25–23.58); respiratory, thoracic, and mediastinal disorders (ROR = 1.92, 95% CI 1.57–2.34); infections and infestations (ROR = 1.39, 95% CI 1.09–1.76); blood and lymphatic system disorders (ROR = 9.57, 95% CI 6.17–14.84); and immune system disorders (ROR = 6.41, 95% CI 3.14–13.12). Moreover, amivantamab was associated with higher risks of thrombosis events, bone marrow suppression, skin and soft tissue infection, deterioration of respiratory symptoms, and noninfectious pneumonitis. The safety profile of amivantamab requires attention; particularly, monitoring of the adverse drug events described above is necessary during its administration.
sj-pdf-1-trc-10.1177_19400829211031171 - Supplemental material for Negative Effects of Logging on Bird Dispersed Plants in Northern Papuan Lowland Forest, Indonesia
Creators: name: Pangau-Adam, Margaretha
name: Slowik, Jolanta
name: Trei, Jan-Niklas
name: Waltert, Matthias
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Geography
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, sj-pdf-1-trc-10.1177_19400829211031171 for Negative Effects of Logging on Bird Dispersed Plants in Northern Papuan Lowland Forest, Indonesia by Margaretha Pangau-Adam, Jolanta Slowik, Jan-Niklas Trei and Matthias Waltert in Tropical Conservation Science
Influenza A(H1N1)v in Germany: the first 10,000 cases
Creators: name: Gilsdorf, Andreas
name: Poggensee, Gabriele
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2009
Subjects: subject: Adolescent
subject: 80 and over
subject: Preschool
subject: Newborn
subject: Human/epidemiology
subject: Humans
subject: Female
subject: Germany/epidemiology
subject: Male
subject: Middle Aged
subject: Incidence
subject: Population Surveillance
subject: Risk Assessment/methods
subject: Risk Factors
subject: Child
subject: Adult
subject: Aged
subject: Infant
subject: Communicable Diseases
subject: Emerging/epidemiology
subject: Influenza A Virus
subject: Influenza
subject: Disease Outbreaks/statistics & numerical data
subject: Young Adult
subject: H1N1 Subtype
subject: 610 Medizin

description: The analysis of the first 10,000 cases of influenza A(H1N1)v in Germany confirms findings from other sources that the virus is currently mainly causing mild diseases, affecting mostly adolescents and young adults. Overall hospitalisation rate for influenza A(H1N1)v was low (7%). Only 3% of the cases had underlying conditions and pneumonia was rare (0.4%). Both reporting and testing requirements have been adapted recently, taking into consideration the additional information available on influenza A(H1N1)v infections.
sj-pdf-2-tia-10.1177_23312165211027688 - Supplemental material for Listening Effort Is Not the Same as Speech Intelligibility Score
Creators: name: Winn, Matthew B.
name: Teece, Katherine H.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-2-tia-10.1177_23312165211027688 for Listening Effort Is Not the Same as Speech Intelligibility Score by Matthew B. Winn and Katherine H. Teece in Trends in Hearing
Safety assessment of esomeprazole: real-world adverse event signal mining and analysis based on FAERS database
Creators: name: Wang, Bojing
name: Huang, Shu
name: Li, Shiqi
name: Deng, Yaqi
name: Li, Ziyan
name: Wang, Yizhou
name: Shi, Xiaomin
name: Zhang, Wei
name: Shi, Lei
name: Tang, Xiaowei
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Esomeprazole holds a significant position in the treatment of acid-related diseases. However, as with all drugs, it may also carry some potential risk of adverse effects. This study aims to further evaluate the safety of esomeprazole for clinical use. The data of esomeprazole-related adverse events was extracted from the FAERS database from the first quarter of 2004 to the first quarter of 2024 and used Reporting Odds Ratios (ROR), Proportional Reporting Ratios (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Empirical Bayes Geometric Mean(EBGM) for data mining. A total of 67,712 esomeprazole-related adverse events were extracted from the FAERS database, involving 27 system organ class. The frequency of renal and urinary occurrence was the highest, and the signal was the strongest. Additionally, we detected 324 preferred terms: rebound acid hypersecretion, nephrogenic anemia, and hyperparathyroidism secondary showed significant high signal strength. In the elderly, adverse events were concentrated in the gastrointestinal disorders system, and the most common adverse events were dyspepsia and hyponatremia. Unexpected adverse events, such as vomiting, acute kidney injury, and anaphylactic reaction occurred in children. We discovered some new and special esomeprazole-related adverse events, raising awareness of the safety of esomeprazole and further helping to mitigate associated risks.
Additional file 1 of Integration of scRNA-seq data by disentangled representation learning with condition domain adaptation
Creators: name: Liu, Renjing
name: Qian, Kun
name: He, Xinwei
name: Li, Hongwei
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1 is a supplementary pdf file that contains method details, evaluation metrics and results along with relevant figures and tables omitted from the manuscript.
Massive Data K-means Clustering and Bootstrapping via A-optimal Subsampling
Creators: name: Zhou, Dali
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Statistics not elsewhere classified

description: For massive data analysis, the computational bottlenecks exist in two ways. Firstly, the data could be too large that it is not easy to store and read. Secondly, the computation time could be too long. To tackle these problems, parallel computing algorithms like Divide-and-Conquer were proposed, while one of its drawbacks is that some correlations may be lost when the data is divided into chunks. Subsampling is another way to simultaneously solve the problems of the massive data analysis while taking correlation into consideration. The uniform sampling is simple and fast, but it is inefficient, see detailed discussions in Mahoney (2011) and Peng and Tan (2018). The bootstrap approach uses uniform sampling and is computing time intensive, which will be enormously challenged when data size is massive. k-means clustering is standard method in data analysis. This method does iterations to find centroids, which would encounter difficulty when data size is massive. In this thesis, we propose the approach of optimal subsampling for massive data bootstrapping and massive data k-means clustering. We seek the sampling distribution which minimize the trace of the variance co-variance matrix of the resulting subsampling estimators. This is referred to as A-optimal in the literature. We define the optimal sampling distribution by minimizing the sum of the component variances of the subsampling estimators. We show the subsampling k-means centroids consistently approximates the full data centroids, and prove the asymptotic normality using the empirical process theory. We perform extensive simulation to evaluate the numerical performance of the proposed optimal subsampling approach through the empirical MSE and the running times. We also applied the subsampling approach to real data. For massive data bootstrap, we conducted a large simulation study in the framework of the linear regression based on the A-optimal theory proposed by Peng and Tan (2018). We focus on the performance of confidence intervals computed from A-optimal subsampling, including coverage probabilities, interval lengths and running times. In both bootstrap and clustering we compared the A-optimal subsampling with uniform subsampling.
International outbreak of Salmonella Oranienburg due to German chocolate.
Creators: name: Werber, Dirk
name: Dreesman, Johannes
name: Feil, Fabian
name: Treeck, Ulrich Van
name: Fell, Gerhard
name: Ethelberg, Steen
name: Hauri, Anja M.
name: Roggentin, Peter
name: Prager, Rita
name: Fisher, Ian ST
name: Behnke, Susanne
name: Bartelt, Edda
name: Weise, Ekkehard
name: Ellis, Andrea
name: Siitonen, Anja
name: Andersson, Yvonne
name: Tschäpe, Helmut
name: Kramer, Michael H.
name: Ammon, Andrea
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2005
Subjects: subject: Adolescent
subject: Preschool
subject: Humans
subject: Female
subject: Disease Outbreaks
subject: Germany/epidemiology
subject: Salmonella Food Poisoning/epidemiology
subject: Electrophoresis
subject: Gel
subject: Pulsed-Field/methods
subject: Male
subject: Middle Aged
subject: Canada/epidemiology
subject: Risk Factors
subject: Child
subject: Adult
subject: Case-Control Studies
subject: Aged
subject: Cacao/microbiology
subject: Candy/microbiology
subject: Europe/epidemiology
subject: Food Microbiology
subject: Infant
subject: Salmonella/genetics
subject: Salmonella/isolation & purification
subject: Salmonella Food Poisoning/microbiology
subject: Aged 80 and over
subject: 610 Medizin

description: Background: This report describes a large international chocolate-associated Salmonella outbreak originating from Germany. Methods: We conducted epidemiologic investigations including a case-control study, and food safety investigations. Salmonella (S.) Oranienburg isolates were subtyped by the use of pulsed-field gel electrophoresis (PFGE). Results: From 1 October 2001 through 24 March 2002, an estimated excess of 439 S. Oranienburg notifications was registered in Germany. Simultaneously, an increase in S. Oranienburg infections was noted in other European countries in the Enter-net surveillance network. In a multistate matched case-control study in Germany, daily consumption of chocolate (matched odds ratio [MOR]: 4.8; 95% confidence interval [CI]: 1.3-26.5), having shopped at a large chain of discount grocery stores (MOR: 4.2; CI: 1.2-23.0), and consumption of chocolate purchased there (MOR: 5.0; CI: 1.1-47.0) were associated with illness. Subsequently, two brands from the same company, one exclusively produced for that chain, tested positive for S. Oranienburg. In two other European countries and in Canada chocolate from company A was ascertained that also contained S. Oranienburg. Isolates from humans and from chocolates had indistinguishable PFGE profiles. No source or point of contamination was identified. Epidemiological identification of chocolate as a vehicle of infections required two months, and was facilitated by proxy measures. Conclusions: Despite the use of improved production technologies, the chocolate industry continues to carry a small risk of manufacturing Salmonella-containing products. Particularly in diffuse outbreak-settings, clear associations with surrogates of exposure should suffice to trigger public health action. Networks such as Enter-net have become invaluable for facilitating rapid and appropriate management of international outbreaks.
sj-pdf-1-ijb-10.1177_13670069211022850 – Supplemental material for Language and counterfactual reasoning in Chinese, English and ChineseL1-EnglishL2 reasoners
Creators: name: Bassetti, Bene
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-ijb-10.1177_13670069211022850 for Language and counterfactual reasoning in Chinese, English and ChineseL1-EnglishL2 reasoners by Bene Bassetti in International Journal of Bilingualism
2024 Systematic Review of Evidence-Based Guidelines for Prehospital Care
Creators: name: Martin-Gill, Christian
name: Patterson, P. Daniel
name: Richards, Christopher T.
name: Misra, Anjali J.
name: Potts, Benjamin T.
name: Cash, Rebecca E.
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Science Policy
Cancer

description: Evidence-based guidelines (EBGs) are widely recognized as valuable tools to aggregate and translate scientific knowledge into clinical care. High-quality EBGs can also serve as important components of dissemination and implementation efforts focused on educating emergency medical services (EMS) clinicians about current evidence-based prehospital clinical care practices and operations. We aimed to perform the third biennial systematic review of prehospital EBGs to identify and assess the quality of prehospital EBGs published since 2021. We systematically searched Ovid Medline and EMBASE from January 1, 2021, to June 6, 2023, for publications relevant to prehospital care, based on an organized review of the literature, and focused on providing recommendations for clinical care or operations. Included guidelines were appraised using the National Academy of Medicine (NAM) criteria for high-quality guidelines and scored using the Appraisal of Guidelines for Research and Evaluation (AGREE) II Tool. We identified 33 new guidelines addressing clinical and operational topics of EMS medicine. The most addressed EMS core content areas were time-life critical conditions (n = 17, 51.5%), special clinical considerations (n = 15, 45%), and injury (n = 12, 36%). Seven (21%) guidelines included all elements of the National Academy of Medicine (NAM) criteria for high-quality guidelines, including the full reporting of a systematic review of the evidence. Guideline appraisals by the Appraisal of Guidelines for Research and Evaluation (AGREE) II tool demonstrated modest compliance to reporting recommendations and similar overall quality compared to previously identified guidelines (mean overall domain score 67%, SD 12%), with Domain 5 (“Applicability”) scoring the lowest of the six AGREE II domains (mean score of 53%, SD 13%). This updated systematic review identified and appraised recent guidelines addressing prehospital care and identifies important targets for education of EMS personnel. Continued opportunities exist for prehospital guideline developers to include comprehensive evidence-based reporting into guideline development to facilitate widespread implementation of high-quality EBGs in EMS systems and incorporate the best available scientific evidence into initial education and continued competency activities.
Phylogeny and Disease Association of Shiga toxin-Producing Escherichia coli O91
Creators: name: Mellmann, Alexander
name: Fruth, Angelika
name: Friedrich, Alexander W.
name: Wieler, Lothar H.
name: Harmsen, Dag
name: Werber, Dirk
name: Middendorf, Barbara
name: Bielaszewska, Martina
name: Karch, Helge
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger; Robert Koch-Institut, Infektionsepidemiologie
Year: 2009
Subjects: subject: Adolescent
subject: 80 and over
subject: Preschool
subject: DNA
subject: Humans
subject: Escherichia coli/classification
subject: Escherichia coli/genetics
subject: Escherichia coli Proteins/genetics
subject: Phylogeny
subject: Virulence
subject: Middle Aged
subject: Animals
subject: Child
subject: Adult
subject: Aged
subject: Infant
subject: Sequence Analysis
subject: Shiga-Toxigenic Escherichia coli/genetics
subject: Young Adult
subject: Severity of Illness Index
subject: Bacterial Typing Techniques
subject: Bacterial/analysis
subject: Diarrhea/physiopathology
subject: Diarrhea/virology
subject: Escherichia coli/pathogenicity
subject: Escherichia coli Infections*/physiopathology
subject: Escherichia coli Infections*/virology
subject: Hemolytic-Uremic Syndrome*/physiopathology
subject: Hemolytic-Uremic Syndrome*/virology
subject: 610 Medizin

description: The diversity and relatedness of 100 Shiga toxin–producing Escherichia coli O91 isolates from different patients were examined by multilocus sequence typing. We identified 10 specific sequence types (ST) and 4 distinct clonal groups. ST442 was significantly associated with hemolytic uremic syndrome.
Automatic outbreak detection algorithm versus electronic reporting system.
Creators: name: Straetemans, Masja
name: Altmann, Doris
name: Eckmanns, Tim
name: Krause, Gérard
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2008
Subjects: subject: Humans
subject: Gastroenteritis/epidemiology
subject: Germany/epidemiology
subject: Population Surveillance/methods
subject: Disease Outbreaks/statistics & numerical data
subject: Disease Notification/statistics & numerical data
subject: Caliciviridae Infections/epidemiology
subject: Norovirus
subject: Algorithms
subject: Campylobacter Infections/epidemiology
subject: 610 Medizin

description: To determine efficacy of automatic outbreak detection algorithms (AODAs), we analyzed 3,582 AODA signals and 4,427 reports of outbreaks caused by Campylobacter spp. or norovirus during 2005-2006 in Germany. Local health departments reported local outbreaks with higher sensitivity and positive predictive value than did AODAs.
Additional file 3 of Barriers and facilitators of older adults for professional mental health help-seeking: a systematic review
Creators: name: Elshaikh, Usra
name: Sheik, Rayan
name: Saeed, Raghad Khaled Mohammad
name: Chivese, Tawanda
name: Alsayed Hassan, Diana
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Mental Health

description: Additional file 3. NEWCASTLE - OTTAWA QUALITY ASSESSMENT SCALE.
sj-pdf-1-tia-10.1177_23312165211027688 - Supplemental material for Listening Effort Is Not the Same as Speech Intelligibility Score
Creators: name: Winn, Matthew B.
name: Teece, Katherine H.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: 110315 Otorhinolaryngology
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-tia-10.1177_23312165211027688 for Listening Effort Is Not the Same as Speech Intelligibility Score by Matthew B. Winn and Katherine H. Teece in Trends in Hearing
Analysis of sieve holes blocking in a vibrating screen and a rotary and drum screen
Creators: name: Lawinska, Katarzyna
name: Modrzewski, Remigiusz
Publisher: name: Faculty of Geoengineering, Mining and Geology, Wrocław University of Technology, Wrocław
Year: 2017
Subjects: sieve
screen blocking
screening machines

description: Physicochemical Problems of Mineral Processing; ISSN 2084-4735
Preparation of activated bentonite and its adsorption behavior on oil-soluble green pigment
Creators: name: Renji, Zheng
name: Huimin, Gao
name: Zijie, Ren
name: Duidui, Cen
name: Zhijie, Chen
Publisher: name: Faculty of Geoengineering, Mining and Geology, Wrocław University of Technology, Wrocław
Year: 2017
Subjects: activated bentonite
acid activation
microwave heating
oil-soluble green pigment
adsorption

description: Physicochemical Problems of Mineral Processing; ISSN 2084-4735
AUTOMATED WEED DETECTION USING MACHINE LEARNING TECHNIQUES ON UAS-ACQUIRED IMAGERY
Creators: name: Etienne, Aaron
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Agricultural engineering

description: Current methods of broadcast herbicide application cause a negative environmental and economic impact. Computer vision methods, specifically those related to object detection, have been reported to aid in site-specific weed management procedures to target apply herbicide on per-weed basis within a field. However, a major challenge to developing a weed detection system is the requirement for properly annotated training data to differentiate between weeds and crops under field conditions. This research involved creating an annotated database of weeds by using UAS-acquired imagery from corn and soybean research plots located in North-central Indiana. A total of 27,828 RGB; 108,398 multispectral; and 23,628 thermal images, were acquired using FLIR Duo Pro R sensor that was attached to a DJI Matrice 600 Pro UAS. An annotated database of 306 RGB images, organized into monocot and dicot weed classes, was used for network training. Two Deep Learning networks namely, DetectNet and You Only Look Once version 3 (YOLO ver3) were subjected to five training stages using four annotated image sets. The precision for weed detection ranged between 3.63-65.37% for monocot and 4.22-45.13% for dicot weed detection. This research has demonstrated a need for creating a large annotated weed database for improving precision of deep learning algorithms through better training of the network.
Challenges and Perceived Impacts of Ambulance Diversions During Emergency Department Overcrowding: A Multi-Stakeholder Study
Creators: name: Rao, Kailing Adriel
name: Wee, Erin Y. Q.
name: Oh, Anna
name: Hao, Desmond Mao Ren
name: Doctor, Nausheen
name: Ong, Marcus E.H.
name: Yoon, Sungwon
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Biotechnology
Cancer
Science Policy

description: Ambulance diversion has emerged as a strategy to address Emergency Department (ED) overcrowding, but the question of when or whether diversion should be triggered is widely debated. Although the positive and adverse impacts of diversion have been primarily studied using quantitative data, little is known about the experience and perceptions of key stakeholders involved in diversions. Our study aims to explore the challenges and impacts of ambulance diversion as experienced by key stakeholders and their suggestions for improving the diversion process. We conducted semi-structured interviews with key stakeholders including physicians, nurses and paramedics across two EDs and four fire stations. All interviews were audio-recorded following consent and transcribed verbatim. The transcripts were subjected to thematic analysis to identify key themes and sub-themes. Coding discrepancies were resolved through iterative discussions until no new themes were identified. A total of 33 stakeholders were interviewed. The primary reasons for ambulance diversions were perceived to be resource constraints in EDs, overcrowding and bed block situations. Challenges during diversions included communication breakdowns, operational delays, lack of clarity in diversion criteria and emotional stress for both Emergency Medical Services (EMS) and hospital staff. Participants felt diversions impacted patient safety, staff morale, system efficiency and could generate inter-institutional conflict. Suggestions on improvements focused on use of alternative care pathways, improving hospital’s flow issues, better information sharing, and optimizing the diversion process through strategizing the timing and duration of diversions. Reworking the hierarchical approach of dissemination of information to ground staff was also suggested. This study highlights that while diversions may offer temporary relief for overwhelmed hospitals, they also pose challenges and negative impacts on receiving hospitals and EMS operations. Our findings underscore the need for systemic improvements to address the root causes of ED overcrowding and enhance understanding among stakeholders involved in diversions.
Additional file 1 of Associations of physical activity intensity, frequency, duration, and volume with the incidence of sarcopenia in middle-aged and older adults: a 4-year longitudinal study in China
Creators: name: Zhao, Xiaoguang
name: Liu, Dongxue
name: Zhang, Hongjun
name: Shen, Shaoshuai
name: Zhang, Naipeng
name: Pan, Yihan
name: Fu, Chao
name: Wang, Wenjiao
name: Ren, Hang
name: Pan, Xiaopeng
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Statistics
subject: FOS: Mathematics
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1: The characteristics of study participants at baseline in 2011 according to the missing data
UAV DETECTION SYSTEM WITH MULTIPLE ACOUSTIC NODES USING MACHINE LEARNING MODELS
Creators: name: Yang, Bowon
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Applied computing not elsewhere classified

description: This paper introduced a near real-time acoustic unmanned aerial vehicle detection system with multiple listening nodes using machine learning models. An audio dataset was collected in person by recording the sound of an unmanned aerial vehicle flying around as well as the sound of background noises. After the data collection phase, support vector machines and convolutional neural networks were built with two features, Mel-frequency cepstral coefficients and short-time Fourier transform. Considering the near real-time environment, the features were calculated after cutting the audio stream into chunks of two, one or half seconds. There are four combinations of features and models as well as three versions per combination based on the chunk size, returning twelve models in total. To train support vector machines, the exhaustive search method was used to find the best parameter while convolutional neural networks were built by selecting the parameters manually. Four node configurations were devised to find the best way to place six listening nodes. Twelve models were run for each configuration, generating color maps to show the paths of the unmanned aerial vehicle flying along the nodes. The model of short-time Fourier transform and support vector machines showed the path most clearly with the least false negatives with 2-second chunk size. Among the four configurations, the configuration for experiment 3 showed the best results in terms of the distance of detection results on the color maps. Web-based monitoring dashboards were provided to enable users to monitor detection results.
Houck Formatted Diss Final.pdf
Creators: name: Houck, Christa Anne
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Psychophysiology

description: Infusion of a dopamine D1-receptor antagonist into both the dorsolateral and dorsomedial striatum interfered with quinine-resistant alcohol drinking, but not unadulterated alcohol consumption. Dopamine in these two brain regions play a role in compulsive-like alcohol consumption.