cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A Constraint to the Parity-Conserving Parameter of the Neutron-Antineutron Oscillations
Creators: name: Krivoruchenko, M. I.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The phenomenology of neutrino oscillations is extended to the neutron- antineutron oscillations predicted by the grand unified theories. There are six parameters in general describing the one-flavor oscillations: two real Majorana masses (of opposite signs), three Euler's angles, and a phase multiplier "chi". The sum of the Majorana masses, treated as a small parity- violating parameter "epsilon", induces the nuclear decays (A,Z) -> (A-2,Z) and determines the oscillation rate of neutrons in the vacuum. We derive a constraint to a small parity-conserving parameter "epsilon-prime" representing a combination of two Euler's angles. This parameter gives no significant contribution to the neutron oscillation rate in the vacuum, while contributes to the nuclear decay rate. The nuclear stability implies "epsilon-prime" < 1/year. Absence of the vacuum neutron oscillations together with existence of the nuclear decays (A,Z) -> (A-2,Z) would become simplest manifestation of the "epsilon-prime" =/ 0.
description: 5 pages, fugure is available upon request by FAX, general treatment of the neutron mixing parameters
Parents’ life satisfaction prior to and following preterm birth
Creators: name: Eves, Robert
name: Baumann, Nicole
name: Bilgin, Ayten
name: Schnitzlein, Daniel
name: Richter, David
name: Wolke, Dieter
name: Lemola, Sakari
Publisher: name: [London] : Macmillan Publishers Limited, part of Springer Nature
Year: 2023
Subjects: subject: menthal-health
subject: posttraumatic-stress
subject: outcomes
subject: depression
subject: infants
subject: Dewey Decimal Classification::500 | Naturwissenschaften
subject: Dewey Decimal Classification::600 | Technik

description: The current study tested whether the reported lower wellbeing of parents after preterm birth, relative to term birth, is a continuation of a pre-existing diference before pregnancy. Parents from Germany (the German Socio-Economic Panel Study, N= 10,649) and the United Kingdom (British Household Panel Study and Understanding Society, N= 11,012) reported their new-born’s birthweight and gestational age, subsequently categorised as very preterm or very low birthweight (VP/VLBW, < 32 weeks or < 1500 g), moderately/late preterm or low birthweight (MLP/LBW, ≥32 weeks and < 37 weeks/≥ 1500 g and < 2500 g), or term-born (≥ 37 weeks and ≥ 2500 g). Mixed models were used to analyse life satisfaction, an aspect of wellbeing, at four assessments-two years and six months before birth and six months and two years afterwards. Two years before birth, satisfaction of prospective term-born, MLP/LBW, or VP/VLBW mothers did not signifcantly difer. However, mothers of VP/ VLBWs had lower satisfaction relative to mothers of term-borns at both assessments post-birth. Among fathers, satisfaction levels were similarly equivalent two years before birth. Subsequently, fathers of VP/VLBWs temporarily difered in satisfaction six months post-birth relative to fathers of term-borns. Results indicate that parents’ lower life satisfaction after VP/VLBW birth is not a continuation of pre-existing life satisfaction diferences.
Host obesity alters the ovarian tumor immune microenvironment and impacts response to standard of care chemotherapy
Creators: name: Liu, Yueying
name: Yang, Jing
name: Hilliard, Tyvette S.
name: Wang, Zhikun
name: Johnson, Jeff
name: Wang, Wanrui
name: Harper, Elizabeth I.
name: Ott, Connor
name: O'Brien, Caitlin
name: Campbell, Leigh
name: Crowley, Brian
name: Grisoli, Stephen
name: Stavrou, Nicholas M.
name: Juncker-Jensen, Anna
name: Stack, M. Sharon
Publisher: name: University of Notre Dame
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences

description: Background: The majority of women with epithelial ovarian cancer (OvCa) are diagnosed with metastatic disease, resulting in a poor 5-year survival of 31%. Obesity is a recognized non-infectious pandemic that increases OvCa incidence, enhances metastatic success and reduces survival. We have previously demonstrated a link between obesity and OvCa metastatic success in a diet-induced obesity mouse model wherein a significantly enhanced tumor burden was associated with a decreased M1/M2 tumor-associated macrophage ratio (Liu Y et al. Can, Res. 2015; 75:5046-57).Methods: The objective of this study was to use pre-clinical murine models of diet-induced obesity to evaluate the effect of a high fat diet (HFD) on response to standard of care chemotherapy and to assess obesity-associated changes in the tumor microenvironment. Archived tumor tissues from ovarian cancer patients of defined body mass index (BMI) were also evaluated using multiplexed immunofluorescence analysis of immune markers.Results: We observed a significantly diminished response to standard of care paclitaxel/carboplatin chemotherapy in HFD mice relative to low fat diet (LFD) controls. A corresponding decrease in the M1/M2 macrophage ratio and enhanced tumor fibrosis were observed both in murine DIO studies and in human tumors from women with BMI > 30.Conclusions: Our data suggest that the reported negative impact of obesity on OvCa patient survival may be due in part to the effect of the altered M1/M2 tumor-associated macrophage ratio and enhanced fibrosis on chemosensitivity. These data demonstrate a contribution of host obesity to ovarian tumor progression and therapeutic response and support future combination strategies targeting macrophage polarization and/or fibrosis in the obese host.
The stock-flow-service nexus: new directions for social-ecological transformation research
Creators: name: Görg, Christoph
name: Wiedenhofer, Dominik
name: Pichler, Melanie
name: Plank, Christina
name: Haberl, Helmut
Publisher: name: Zenodo
Year: 2019

description: Presentation on "The stock-flow-service nexus: new directions for social-ecological transformation research" given at the 4th OSM – GLP, Bern, 26.April 2019
Anomaly and quantum corrections to solitons in two-dimensional theories with minimal supersymmetry
Creators: name: Shifman, M.
name: Vainshtein, A.
name: Voloshin, M.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We reexamine the issue of the soliton mass in two-dimensional models with N =1 supersymmetry. The superalgebra has a central extension, and at the classical level the soliton solution preserves 1/2 of supersymmetry which is equivalent to BPS saturation. We prove that the property of BPS saturation, i.e. the equality of the soliton mass to the central charge, remains intact at the quantum level in all orders of the weak coupling expansion. Our key finding is an anomaly in the expression for the central charge. The classical central charge, equal to the jump of the superpotential, is amended by an anomalous term proportional to the second derivative of the superpotential. The anomaly is established by various methods in explicit one-loop calculations. We argue that this one-loop result is not affected by higher orders. We discuss in detail how the impact of the boundary conditions can be untangled from the soliton mass calculation. In particular, the soliton profile and the energy distribution are found at one loop. A "supersymmetry" in the soliton mass calculations in the non-supersymmetric models is observed.
description: 50 pages, LaTex, 2 figures. The version exactly matching that published in Phys.Rev. D. The most essential addition is a footnote, clarifying multiplet shortening
Erebia scipio Boisduval 1832
Creators: name: Bonelli, Simona
name: Barbero, Francesca
name: Casacci, Luca Pietro
name: Cerrato, Cristiana
name: Balletto, Emilio
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Nymphalidae
Erebia
Erebia scipio

description: Erebia scipio Boisduval, 1832
Erebia scipio Boisduval, 1832: 152.
FIRST RECORD FOR THE VALDIERI AREA. — Turati & Verity (1911).
CHOROTYPE. — SW Alpine (orophilous).
ECOLOGY. — Screes, upper montane-alpine, mesophilous, xerophilous.
EDIT PROJECT SAMPLING. — Not found. Perhaps extinct in the area (see Rocci 1911).
NOTE Elsewhere in the region, only reported from Balma della Frema, at 2300 m, very close to the border between Italy and France.
description: Published as part of Bonelli, Simona, Barbero, Francesca, Casacci, Luca Pietro, Cerrato, Cristiana & Balletto, Emilio, 2015, The butterfly fauna of the Italian Maritime Alps: results of the EDIT project, pp. 139-167 in Zoosystema 37 (1) on page 161, DOI: 10.5252/z2015n1a6, http://zenodo.org/record/5154896
3D-ResNet-BiLSTM Model: A Deep Learning Model for County-Level Soybean Yield Prediction with Time-Series Sentinel-1, Sentinel-2 Imagery, and Daymet Data
Creators: name: Fathi, Mahdiyeh
name: Shah-Hosseini, Reza
name: Moghimi, Armin
Publisher: name: Basel : MDPI
Year: 2023
Subjects: subject: BiLSTM
subject: Conv3D
subject: Daymet
subject: Google Earth Engine (GEE)
subject: ResNet
subject: Sentinel 1–2
subject: soybean
subject: yield prediction
subject: Dewey Decimal Classification::600 | Technik::620 | Ingenieurwissenschaften und Maschinenbau

description: Ensuring food security in precision agriculture requires early prediction of soybean yield at various scales within the United States (U.S.), ranging from international to local levels. Accurate yield estimation is essential in preventing famine by providing insights into food availability during the growth season. Numerous deep learning (DL) algorithms have been developed to estimate soybean yield effectively using time-series remote sensing (RS) data to achieve this goal. However, the training data with short time spans can limit their ability to adapt to the dynamic and nuanced temporal changes in crop conditions. To address this challenge, we designed a 3D-ResNet-BiLSTM model to efficiently predict soybean yield at the county level across the U.S., even when using training data with shorter periods. We leveraged detailed Sentinel-2 imagery and Sentinel-1 SAR images to extract spectral bands, key vegetation indices (VIs), and VV and VH polarizations. Additionally, Daymet data was incorporated via Google Earth Engine (GEE) to enhance the model’s input features. To process these inputs effectively, a dedicated 3D-ResNet architecture was designed to extract high-level features. These enriched features were then fed into a BiLSTM layer, enabling accurate prediction of soybean yield. To evaluate the efficacy of our model, its performance was compared with that of well-known models, including the Linear Regression (LR), Random Forest (RF), and 1D/2D/3D-ResNet models, as well as a 2D-CNN-LSTM model. The data from a short period (2019 to 2020) were used to train all models, while their accuracy was assessed using data from the year 2021. The experimental results showed that the proposed 3D-Resnet-BiLSTM model had a superior performance compared to the other models, achieving remarkable metrics (R2 = 0.791, RMSE = 5.56 Bu Ac−1, MAE = 4.35 Bu Ac−1, MAPE = 9%, and RRMSE = 10.49%). Furthermore, the 3D-ResNet-BiLSTM model showed a 7% higher R2 than the ResNet and RF models and an enhancement of 27% and 17% against the LR and 2D-CNN-LSTM models, respectively. The results highlighted our model’s potential for accurate soybean yield predictions, supporting sustainable agriculture and food security.
Calculation of Wilson loops in 2-dimensional Yang-Mills theories
Creators: name: Aroca, J. M.
name: Kubyshin, Yu.
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The vacuum expectation value of the Wilson loop functional in pure Yang-Mills theory on an arbitrary two-dimensional orientable manifold is studied. We consider the calculation of this quantity for the abelian theory in the continuum case and for the arbitrary gauge group and arbitrary lattice action in the lattice case. A classification of topological sectors of the theory and the related classification of the principal fibre bundles over two-dimensional surfaces are given in terms of a cohomology group. The contribution of SU(2)-invariant connections to the vacuum expectation value of the Wilson loop variable is also analyzed and is shown to be similar to the contribution of monopoles.
description: 46 pages, Latex, 5 figures included (psfig, epsfig)
Big data analytics and processing for urban surveillance systems
Creators: name: Hu, Ling
Publisher: name: Lancaster University
Year: 2019
Subjects: Big Data Analytics
Urban Surveillance Systems

description: Urban surveillance systems will be more demanding in the future towards smart city to improve the intelligence of cities. Big data analytics and processing for urban surveillance systems become increasingly important research areas because of infinite generation of massive data volumes all over the world. This thesis focused on solving several challenging big data issues in urban surveillance systems. First, we proposed several simple yet efficient video data recoding algorithms to be used in urban surveillance systems. The key idea is to record the important video frames when cutting the number of unimportant video frames. Second, since the DCT based JPEG standard encounters problems such as block artifacts, we proposed a very simple but effective method which results in better quality than widely used filters while consuming much less computer CPU resources. Third, we designed a novel filter to detect either the vehicle license plates or the vehicles from the images captured by the digital camera imaging sensors. We are the first to design this kind of filter to detect the vehicle/license plate objects. Fourth, we proposed novel grate filter to identify whether there are objects in these images captured by the cameras. In this way the background images can be updated from time to time when no object is detected. Finally, we combined image hash with our novel density scan method to solve the problem of retrieving similar duplicate images.
MOESM4 of Specificity of the IgG antibody response to Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale MSP119 subunit proteins in multiplexed serologic assays
Creators: name: Priest, Jeffrey
name: Plucinski, Mateusz
name: Huber, Curtis
name: Rogier, Eric
name: Bunsoth Mao
name: Gregory, Christopher
name: Candrinho, Baltazar
name: Colborn, James
name: Barnwell, John
Publisher: name: figshare
Year: 2018
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 4. Additional MSP119 antibody binding and elution assays using beads coated with Plasmodium ovale (Po) or Plasmodium malariae (Pm) antigens.
title: 02_1781
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Elastic neutrino - electron scattering and potential effects of magnetic and electric dipole moments
Creators: name: Grimus, W.
name: Schwetz, T.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider elastic neutrino - electron scattering of solar neutrinos with magnetic moments and electric dipole moments, where the solar neutrino state at the scattering site is determined by the evolution in matter and solar magnetic fields of the initial electron neutrino state. We present the general cross section for an arbitrary superposition of active and sterile neutrino types with positive and negative helicities, with particular emphasis on the effect of transverse polarization, which gives rise to an azimuthal asymmetry as a function of the recoil electron momentum. Within our physically motivated approximation, we perform a general CP analysis and show that in the 1-Dirac and 2-Majorana neutrino cases no CP-violating effects are present, which means that it is not possible to distinguish between magnetic and electric dipole moments in these cases. We also study the consequences of neutrino energy averaging on the cross section and stress that in the 2-Majorana neutrino case this averaging leads to a suppression of the transverse neutrino polarization effects.
description: Revtex, 23 pages, no figures
Non-Markovian dynamics revealed at the bound state in continuum
Creators: name: Garmon, Savannah
name: Noba, Kenichi
name: Ordonez, Gonzalo
name: Segal, Dvira
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a methodical approach to controlling and enhancing deviations from exponential decay in quantum and optical systems by exploiting recent progress surrounding another subtle effect: the bound states in continuum, which have been observed in optical waveguide array experiments within this past decade. Specifically, we show that by populating an initial state orthogonal to that of the bound state in continuum, it is possible to engineer system parameters for which the usual exponential decay process is suppressed in favor of inverse power law dynamics and coherent effects that typically would be extremely difficult to detect in experiment. We demonstrate our method using a model based on an optical waveguide array experiment, and further show that the method is robust even in the face of significant detuning from the precise location of the bound state in continuum.
Preclinical pharmacokinetic investigation of the bioavailability and skin distribution of HY-072808 ointment, a novel drug candidate for the treatment of atopic dermatitis, in minipigs by a newly LC-MS/MS method
Creators: name: Shao, Li
name: Mo, Jiajia
name: Xu, Qinlong
name: He, Guangwei
name: Xing, Chunyu
name: Chu, Zhaoxing
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: HY-072808 is a novel phosphodiesterase 4 inhibitor clinically used for topical atopic dermatitis treatment. Cytochrome P450 enzymes are involved in transforming it into major metabolite ZZ-24. An efficient UPLC–MS/MS method was established to detect HY-072808 and ZZ-24 in plasma and skin tissues of minipigs.One-step protein precipitation was performed with acetonitrile. Subsequently, elution was served with a methanol and water gradient containing 0.1% formic acid for 3.5 min. The plasma and skin tissue concentrations of HY-072808 and ZZ-24 showed good linearity from 0.200 to 200 ng/mL.The experimental minipigs exhibited low systemic exposure and bioavailability of 3.1–7.6% after transdermal application of 1–4% HY-072808 ointment. Multiple topical administrations over seven consecutive days showed a minor accumulation in systemic exposure, with accumulation factors of 2.3 and 4.0 for HY-072808 and ZZ-24, respectively.The distribution of HY-072808 ointment among different cortical layers in minipigs was studied for the first time. Following transdermal application of 2% HY-072808 ointment, the concentration in plasma and skin tissues in the order of epidermis > dermis > subcutaneous tissue ≈ subcutaneous muscle ≈ plasma; at 48 h after the administration, the epidermis and dermis still had a high concentration of the drug.
Additional file 5 of Comprehensive analysis of m6A related gene mutation characteristics and prognosis in colorectal cancer
Creators: name: Jiang, Tao
name: Xing, Linshuai
name: Zhao, Lipeng
name: Ye, Ziqi
name: Yu, Dong
name: Lin, Shengtao
Publisher: name: figshare
Year: 2023
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 5. YTHDC: Analysis of the correlation between m6a regulators and clinical stage. Results of correlation between YTHDC2 and clinical stage (p > 0.05).
Core electron binding energies of adsorbates on Cu(111) from first-principles calculations
Creators: name: Kahk, J. Matthias
name: Lischner, Johannes
Publisher: name: arXiv
Year: 2018
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Core-level X-ray Photoelectron Spectroscopy (XPS) is often used to study the surfaces of heterogeneous copper-based catalysts, but the interpretation of measured spectra, in particular the assignment of peaks to adsorbed species, can be extremely challenging. In this study we demonstrate that first principles calculations using the delta Self Consistent Field (delta-SCF) method can be used to guide the analysis of experimental core-level spectra of complex surfaces relevant to heterogeneous catalysis. Specifically, we calculate core-level binding energy shifts for a series of adsorbates on Cu(111) and show that the resulting C1s and O1s binding energy shifts for adsorbed CO, CO2, C2H4, HCOO, CH3O, H2O, OH and a surface oxide on Cu(111) are in good overall agreement with the experimental literature. In the few cases where the agreement is less good, the theoretical results may indicate the need to re-examine experimental peak assignments.
description: 11 pages, 5 figures
Harnessing AI for Speech Reconstruction using Multi-view Silent Video Feed
Creators: name: Kumar, Yaman
name: Aggarwal, Mayank
name: Nawal, Pratham
name: Satoh, Shin'ichi
name: Shah, Rajiv Ratn
name: Zimmerman, Roger
Publisher: name: arXiv
Year: 2018
Subjects: subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Speechreading or lipreading is the technique of understanding and getting phonetic features from a speaker's visual features such as movement of lips, face, teeth and tongue. It has a wide range of multimedia applications such as in surveillance, Internet telephony, and as an aid to a person with hearing impairments. However, most of the work in speechreading has been limited to text generation from silent videos. Recently, research has started venturing into generating (audio) speech from silent video sequences but there have been no developments thus far in dealing with divergent views and poses of a speaker. Thus although, we have multiple camera feeds for the speech of a user, but we have failed in using these multiple video feeds for dealing with the different poses. To this end, this paper presents the world's first ever multi-view speech reading and reconstruction system. This work encompasses the boundaries of multimedia research by putting forth a model which leverages silent video feeds from multiple cameras recording the same subject to generate intelligent speech for a speaker. Initial results confirm the usefulness of exploiting multiple camera views in building an efficient speech reading and reconstruction system. It further shows the optimal placement of cameras which would lead to the maximum intelligibility of speech. Next, it lays out various innovative applications for the proposed system focusing on its potential prodigious impact in not just security arena but in many other multimedia analytics problems.
description: 2018 ACM Multimedia Conference (MM '18), October 22--26, 2018, Seoul, Republic of Korea
The Hagedorn Transition, Deconfinement and the AdS/CFT Correspondence
Creators: name: Rama, S. Kalyana
name: Sathiapalan, B.
Publisher: name: arXiv
Year: 1998
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A connection between the Hagedorn transition in string theory and the deconfinement transition in (non-supersymmetric) Yang-Mills theory is made using the AdS/CFT correspondence. We modify the model of zero temperature QCD proposed by Witten by compactifying an additional space-time coordinate with supersymmetry breaking boundary conditions thus introducing a finite temperature in the boundary theory. There is a Hagedorn-like transition associated with winding modes around this coordinate, which signals a topology changing phase transition to a new AdS/Schwarzschild blackhole where this coordinate is the time coordinate. In the boundary gauge theory time like Wilson loops acquire an expectation value above this temperature.
description: Latex file, 10 Pages
Interleaved Atom Interferometry for High Sensitivity Inertial Measurements
Creators: name: Savoie, D.
name: Altorio, M.
name: Fang, B.
name: Sidorenkov, L. A.
name: Geiger, R.
name: Landragin, A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: Instrumentation and Detectors (physics.ins-det)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Cold-atom inertial sensors target several applications in navigation, geoscience and tests of fundamental physics. Reaching high sampling rates and high inertial sensitivities, obtained with long interrogation times, represents a challenge for these applications. We report on the interleaved operation of a cold-atom gyroscope, where 3 atomic clouds are interrogated simultaneously in an atom interferometer featuring a 3.75 Hz sampling rate and an interrogation time of 801 ms. Interleaving improves the inertial sensitivity by efficiently averaging vibration noise, and allows us to perform dynamic rotation measurements in a so-far unexplored range. We demonstrate a stability of $3\times 10^{-10}$ rad.s$^{-1}$, which competes with the best stability levels obtained with fiber-optics gyroscopes. Our work validates interleaving as a key concept for future atom-interferometry sensors probing time-varying signals, as in on-board navigation and gravity-gradiometry, searches for dark matter, or gravitational wave detection.
Development of a physiologically based pharmacokinetic model for levetiracetam in patients with renal impairment to guide dose adjustment based on steady-state peak/trough concentrations
Creators: name: Wang, Rongrong
name: Wang, Tianlin
name: Han, Xueliang
name: Chen, Mengli
name: Li, Shu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Hematology

description: Levetiracetam may cause acute renal failure and myoclonic encephalopathy at high plasma levels, particularly in patients with renal impairment. The aim of this study was to develop a physiologically based pharmacokinetic (PBPK) model to predict levetiracetam pharmacokinetics in Chinese adults with epilepsy and renal impairment and define appropriate levetiracetam dosing regimen.PBPK models for healthy subjects and epilepsy patients with renal impairment were developed, validated, and adapted. Furthermore, we predicted the steady-state trough and peak concentrations of levetiracetam in patients with renal impairment using the final PBPK model, thereby recommending appropriate levetiracetam dosing regimens for different renal function stages. The predicted maximum plasma concentration (Cmax), time to maximum concentration (Tmax), area under the plasma concentration–time curve (AUC) were in agreement (0.8 ≤ fold error ≤ 1.2) with the observed, and the fold error of the trough concentrations in end-stage renal disease (ESRD) was 0.77 − 1.22. The prediction simulations indicated that the recommended doses of 1000, 750, 500, and 500 mg twice daily for epilepsy patients with mild, moderate, severe renal impairment, and ESRD, respectively, were sufficient to achieve the target plasma concentration of levetiracetam.
Nova V1425 Aquilae 1995 - The Early Appearance of Accretion Processes in An Intermediate Polar Candidate
Creators: name: Retter, A.
name: Leibowitz, E. M.
name: Kovo-Kariti, O.
Publisher: name: arXiv
Year: 1997
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Continuous CCD photometry of Nova Aquilae 1995 was performed through the standard B,V,R and I filters during three nights in 1995 and with the I filter during 18 nights in 1996. The power spectrum of the 1996 data reveals three periodicities in the light curve: 0.2558 d, 0.06005 d and 0.079 d, with peak-to-peak amplitudes of about 0.012, 0.014 and 0.007 mag. respectively. The two shorter periods are absent from the power spectrum of the 1995 light curve, while the long one is probably already present in the light curve of that year. We propose that V1425 Aql should be classified as an Intermediate - Polar CV. Accordingly the three periods are interpreted as the orbital period of the underlying binary system, the spin period of the magnetic white dwarf and the beat period between them. Our results suggest that no later than 15 months after the outburst of the nova, accretion processes are taking place in this stellar system. Matter is being transferred from the cool component, most likely through an accretion disc and via accretion columns on to the magnetic poles of the hot component.
description: 7 pages, 4 eps. figures, Latex, accepted for publication in MNRAS
The metabolism of the orexin-1 selective receptor antagonist nivasorexant
Creators: name: Treiber, Alexander
name: Seeland, Swen
name: Haschimi, Belal
name: Weigel, Aude
name: Williams, Jodi T.
name: Gabillet, Jerome
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Nivasorexant was the first orexin-1 selective receptor antagonist entering clinical development. Despite encouraging preclinical evidence in animal models, a proof-of-concept trial in binge-eating patients recently failed to demonstrate its clinical utility in this population.Across species, nivasorexant clearance was driven by metabolism along seven distinct pathways, five of which were hydroxylation reactions in various locations of the molecule. The exact sites of metabolism were identified by means of mass spectrometry, the use of deuterated analogues, and finally confirmed by chemical references.CYP3A4 was the main cytochrome P450 enzyme involved in nivasorexant metabolism in vitro and accounting for about 90% of turnover in liver microsomes. Minor roles were taken by CYP2C9 and CYP2C19 but individually did not exceed 3–7%.In the rat, nivasorexant was mostly excreted via the bile after extensive metabolism, while urinary excretion was negligible. Only traces of the parent drug were detected in urine, bile, or faeces. Nivasorexant was the first orexin-1 selective receptor antagonist entering clinical development. Despite encouraging preclinical evidence in animal models, a proof-of-concept trial in binge-eating patients recently failed to demonstrate its clinical utility in this population. Across species, nivasorexant clearance was driven by metabolism along seven distinct pathways, five of which were hydroxylation reactions in various locations of the molecule. The exact sites of metabolism were identified by means of mass spectrometry, the use of deuterated analogues, and finally confirmed by chemical references. CYP3A4 was the main cytochrome P450 enzyme involved in nivasorexant metabolism in vitro and accounting for about 90% of turnover in liver microsomes. Minor roles were taken by CYP2C9 and CYP2C19 but individually did not exceed 3–7%. In the rat, nivasorexant was mostly excreted via the bile after extensive metabolism, while urinary excretion was negligible. Only traces of the parent drug were detected in urine, bile, or faeces.
SO(10)-Inspired See-Saw Mechanism
Creators: name: Abud, M.
name: Buccella, F.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We determine the nu_{R} Majorana mass matrix from the experimental data on neutrino oscillations in the framework of a see-saw SO(10) model, where we impose the condition (M^R)_{33} = 0 to avoid too large fine-tunings in the see-saw formula. We find a class of solutions with the two lowest neutrino masses almost degenerate and the scale of the matrix elements of M^R in the range 10^{11} -10^{12} GeV in agreement with Pati-Salam intermediate symmetry. We find also solutions with smaller neutrino masses, for which the scale of M_R depends on the solution to the "solar neutrino problem" and on the value of the component of ν_e along the highest mass eigenstate, U_{e3}.
description: 16 pages, 3 tables, LateX
Ten Dimensional Black Hole and the D0-brane Threshold Bound State
Creators: name: Li, Miao
Publisher: name: arXiv
Year: 1999
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the ten dimensional black holes made of D0-branes in the regime where the effective coupling is large, and yet the 11D geometry is unimportant. We suggest that these black holes can be interpreted as excitations over the threshold bound state. Thus, the entropy formula for the former is used to predict a scaling region of the wave function of the latter. The horizon radius and the mass gap predicted in this picture agree with the formulas derived from the classical geometry.
description: 11 pages, harvmac; v2: typos corrected, argument for the convergence of two integrals improved, v3: one ref. added
Additional file 1 of Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation
Creators: name: Liu, Feng
name: Xie, Jianfeng
name: Zhang, Xiwen
name: Wu, Zongsheng
name: Zhang, Shi
name: Xue, Ming
name: Chen, Jianxiao
name: Yang, Yi
name: Qiu, Haibo
Publisher: name: figshare
Year: 2020
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Figure S1. The therapeutical effects of rTGF-β1 on organs injury in septic mice. The tissue sections were stained with haematoxylin–eosin. (a, b, c): Histopathological images of lung, liver and spleen tissues (H&E staining, 400×). Scale bar = 20 μm. (d, e,f, ): The injury scores of lung、 liver and spleen. (n=3; *p<0.05 vs. sham group; #p<0.05 vs. CLP group; &p<0.05 vs. rTGF-β1 group). Abbreviations: CLP: cecal ligation and puncture; rTGF-β1, recombinant TGF-β1;SB, SB-431542. Figure S2. The body temperature in different groups. (n=3; *p<0.05 vs. sham group; #p<0.05 vs. CLP group). Abbreviations: MSCs: Mesenchymal stem cell; MSC-NC: MSC normal control; MSC-TGF-β1: TGF-β1 overexpressing MSCs. Figure S3. The distribution of MSC-TGF-β1 in septic mice after intravenous infusion at 24 hours. Fluorescence microscopy validation in recipient lung、liver and spleen. MSC-TGF-β1 (green) were observed in the lung、liver and spleen tissues. Nuclei were stained with DAPI (blue). Scale bar=20 μm. Abbreviations: CLP: cecal ligation and puncture; MSC-TGF-β1: TGF-β1 overexpressing MSCs. Figure S4. The level of TGF-β1 in the plasma were tested by ELISA (n = 3, *p<0.05 vs. sham group; #p<0.05 vs. CLP group; &p < .05 vs. MSC-NC group). MSCs: Mesenchymal stem cell; MSC-NC: MSC normal control; MSC-TGF-β1: TGF-β1 overexpressing MSCs. Figure S5. The concentration of inflammatory cytokines in the supernatant of MSC medium. MSCs: Mesenchymal stem cell; MSC-NC: MSC normal control; MSC-TGF-β1: TGF-β1 overexpressing MSCs. Figure S6. Effect of primary peritoneal macrophages treated with MSC-TGF-β1 on organ injury in CLP-induced septic mice. (a): Histopathological images of lung tissues were obtained by H&E (400×). Scale bar=100 μm. (b): Injury scores for the lung from each group. (n = 3, *p < .05 vs. the sham group; #p < .05 vs. the LPS group; &p<0.05 vs. the MSC-Ma group. Abbreviations: Abbreviations: Ma, macrophages; MSCs, mesenchymal stem cell; MSC-Ma, MSCs preconditioned Macrophage; MSC-NC-Ma, MSC-NC preconditioned Macrophage; MSC-TGF-β-Ma, MSC-TGF-β preconditioned macrophage; MSC-NC: mesenchymal stem cell carrying GFP; MSC-TGF-β1: TGF-β1 overexpressing MSC. Figure S7. The identification of MSCs. (A) MSCs surface markers, including CD29, CD44, CD117, Sca-1and CD31 were determined by flow cytometry. (B) The morphology of MSC at the 6th passage (×100) and the multilineage differentiation capacities of MSC, including adipogenic differentiation staining with oil red-O (C, ×200), osteogenic differentiation staining with alizarin red (D, ×200) were observed with a microscope. (Data were provided by Cyagen Bioscience, Inc., Guangzhou, China).
Erebia triaria
Creators: name: Bonelli, Simona
name: Barbero, Francesca
name: Casacci, Luca Pietro
name: Cerrato, Cristiana
name: Balletto, Emilio
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Nymphalidae
Erebia
Erebia triaria

description: Erebia triaria (de Prunner, 1798)
Pap.[ilio] triarius de Prunner, 1798: 70.
FIRST RECORD FOR THE VALDIERI AREA. — Turati & Verity (1911).
CHOROTYPE. — S European (orophilous).
ECOLOGY. — Open herbaceous, upper montane-subalpine, mesophilous, meso-xerophilous.
EDIT PROJECT SAMPLING. — Valasco, Rhododendron heathland, 1690 m, VI.2009, CS.
description: Published as part of Bonelli, Simona, Barbero, Francesca, Casacci, Luca Pietro, Cerrato, Cristiana & Balletto, Emilio, 2015, The butterfly fauna of the Italian Maritime Alps: results of the EDIT project, pp. 139-167 in Zoosystema 37 (1) on page 161, DOI: 10.5252/z2015n1a6, http://zenodo.org/record/5154896
MOESM3 of Effects of pH on steam explosion extraction of acetylated galactoglucomannan from Norway spruce
Creators: name: Michalak, Leszek
name: Knutsen, Svein
name: Aarum, Ida
name: Bjørge Westereng
Publisher: name: figshare
Year: 2018
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry

description: Additional file 3: Table S1. Determination of the 13C/1H correlation signals acquired in the 2D-NMR HSQC spectrum of MWL spruce. β-O-4 reflect the β-aryl ether as sketched in Additional file 1: Figure S1, G2, -5 and -6-reflects the aromatic signals and MeO reflects the methoxyl-group in the guaiacyl units sketched in Additional file 1: Figure S1. Table S2. Monosaccharide composition of carbohydrates in freeze dried aliquots of filtered, water soluble fractions. Table S3. Monosaccharide composition of dried residual biomass. Table S4. Acetate present in filtered slurry and released from solubilized carbohydrates in KOH treatment. Data from Fig. 2b, c and d.
Degradation of Tetrabromobisphenol S by thermo-activated Persulphate Oxidation: reaction Kinetics, transformation Mechanisms, and brominated By-products
Creators: name: Wang, Lu
name: Yu, Yaqun
name: Liu, Guoqiang
name: Hu, Baowei
name: Lu, Junhe
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Brominated flame retardants (BFRs) are a group of contaminants of emerging environmental concern. In this study, systematic exploration was carried out to investigate the degradation of tetrabromobisphenol S (TBBPS), a typical emerging BFRs, by thermally activated persulfate (PDS) oxidation. The removal of 5.0 μM TBBPS was 100% after 60 min oxidation treatment under 60°C. Increasing the temperature or initial PDS concentration facilitated the degradation efficiency of TBBPS. The quenching test indicated that TBBPS degradation occurred via the attack of both sulphate radicals and hydroxyl radicals. Natural organic matter (NOM) decreased the removal rate, however, complete disappearance of TBBPS could still be obtained. Six intermediate products were formed during reactions between TBBPS and radicals. Transformation pathways including debromination, β-Scission, and cross-coupling were proposed. Brominated disinfection by-products (DBPs) in situ formed during the degradation of TBBPS were also investigated, such as bromoform and dibromoacetic acid. The presence of NOM reduced the formation rates of brominated DBPs. Results reveal that although thermo-activated PDS is a promising method for TBBPS-contaminated water, it can lead to potential brominated DBPs risks, which should be paid more attention to when SO4•−-based oxidation technology is applied.
La mansión del tirano
Creators: name: Carlos, Liscano
name: Liscano, Carlos
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: Prison
Dictature
Cárcel
Dictadura

description: Manuscrit original de "La mansión del tirano".
description: Manuscrito original de "La mansión del tirano".
description: Notes/Notas : Stylo noir. Pages numérotées au stylo rouge. 2 pages 75 (a et b), 4 pages 95 (a, b, c et d), absence des pages 128 et 129). Un texte ajouté au stylo bleu à la fin du manuscrit, p. 144 [1984-09-28]
description: Bolígrafo negro. Páginas numeradas con Bolígrafo rojo. 2 páginas 75 (a y b), 4 páginas 95 (a, b, c y d), no hay páginas 128 et 129). Un texto añadido al final del manuscrito con Bolígrafo azul pág. 144 [1984-09-28].
description: Source: Cote / Código : CL-AA3-03-C0
description: Source: Localisation / Ubicación del archivo : Archivo Carlos Liscano – Montevideo, Uruguay
description: Bibliographic citation: Liscano, Carlos, « La mansión del tirano, Montevideo », Arca, 1992; edición anotada por el autor, Montevideo, Argumento, 2011.
Efficiency of BRDF sampling and bias on the average photometric behavior
Creators: name: Schmidt, Frederic
name: Bourguignon, Sebastien
Publisher: name: arXiv
Year: 2018
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: The Hapke model has been widely used to describe the photometrical behavior of planetary surface through the Bi-directional Reflectance Distribution Function (BRDF), but the uncertainties about retrieved parameters has been difficult to handle so far. A recent study proposed to estimate the uncertainties using a Bayesian approach (Schmidt et al., Icarus 2015). In the present article, we first propose an improved numerical implementation to speed up the uncertainties estimation. Then, we conduct two synthetic studies about photometric measurements in order to analyze the influence of observation geometry: First, we introduce the concept of "efficiency" of a set of geometries to sample the photometric behavior. A set of angular sampling elements (noted as geometry) is efficient if the retrieved Hapke parameters are close to the expected ones. We compared different geometries and found that the principal plane with high incidence is the most efficient geometry among the tested ones. In particular, such geometries are better than poorly sampled full BRDF. Second, we test the analysis scheme of a collection of photometric data acquired from various locations in order to answer the question: are these locations photometrically homogeneous or not? For instance, this question arises when combining data from an entire planetary body, where each spatial position is sampled at a single geometry. We tested the ability of the Bayesian method to decipher two situations, in the presence of noise: (i) a photometrically homogeneous surface (all observations with the same photometric behavior), or (ii) an heterogeneous surface with two distinct photometrical properties (half observations with photometric behavior 1, other half with photometric behavior 2). We show that the naive interpretation of the results provided by Bayesian method is not able to solve this problem.
description: 32 pages, 5 figures