cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The experience of Saudi female students attending mixed gender ESL courses in Melbourne, Australia
Creators: name: Alghamdi, Sahar Mohamad
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: This study explored the experience of Saudi female students attending mixed-gender English as a second language (ESL) courses in Melbourne, Australia and the factors that impacted their levels of engagement. A transcendental phenomenological research design was used to provide a thick description of the essence of the Saudi female experience in this learning environment. The participants included four Saudi female students currently attending ESL courses in Melbourne, Australia. Two phases—descriptive and interpretive—were employed in the data analysis to accurately capture the nature of the experience.

 This study revealed that, while all the participants held a positive attitude towards their experience, language proficiency level and marital status played crucial roles in their adaptation. Participants with high language skills reported smoother adaptation than students with low language skills. The married students tended to be more inhibited than single students by the attendance of male especially Saudi male. Working solely with males or participating in physical activities with males had the greatest impact on levels of engagement in classroom activities. These findings were broadly in line with the sparse literature available on this phenomenon. Therefore, future research suggestions and practical implications were offered.
Extra Costs of Disablement: Background for an Australian Study
Creators: name: Horn, Robert V
Publisher: name: UNSW Sydney
Year: 1981
Subjects: Australia
People with Disabilities
Costs of Living

description: It is widely assumed that people with disabilities suffer from financial disadvantage and incur extra costs of living which people without disabilities do not have. To live in an advanced industrial society involves costs across a wide range - costs borne by individuals, families, agencies, and governments. We assume but do not know the extent of the extra costs borne by those with disabilities, and the development of a method by which these extra costs may be assessed is imperative. The Social Welfare Research Centre has been fortunate in securing the services of Dr Robert Horn to begin to examine these issues. Unfortunately we have not been able to go beyond an initial examination. This paper is not a research paper. It was not intended to report results nor was it intended to develop theory. It was intended as a first step in developing a study which might examine the extra costs of disablement. The Social Welfare Research Centre is not able to conduct such a survey, nor is it able to develop in detail the component parts of such a survey. We hope, however, that we are performing a service by examining in a systematic way the definitional and conceptual issues that have to be thought through in our search for a better understanding of a social issue of great importance. This working paper deals with severe disablement, and is concerned with daily living costs.
description: Reports and Proceedings; 13
Additional file 16 of Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3
Creators: name: Jing, Yipei
name: Jiang, Xueke
name: Lei, Li
name: Peng, Meixi
name: Ren, Jun
name: Xiao, Qiaoling
name: Tao, Yao
name: Tao, Yonghong
name: Huang, Junpeng
name: Wang, Lu
name: Tang, Yuting
name: Yang, Zailin
name: Yang, Zesong
name: Zhang, Ling
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 16 : Figure S11. EGR1 does not affect the expression of HOTAIRM1. a The efficiency of EGR1 overexpression in OCI-AML3 cells was validated by western blotting. b qRT-PCR was used to detect the expression of HOTAIRM1 in EGR1-enforced OCI-AML3 cells. The data are presented as the mean ± SD of three independent experiments. n.s. indicates no significant difference.
Additional file 1: of Efficient generation of male germ-like cells derived during co-culturing of adipose-derived mesenchymal stem cells with Sertoli cells under retinoic acid and testosterone induction
Creators: name: Luo, Yanxia
name: Xie, Lili
name: Mohsin, Ali
name: Ahmed, Waqas
name: Xu, Chenze
name: Peng, Yan
name: Hang, Haifeng
name: Zhuang, Yingping
name: Chu, Ju
name: Guo, Meijin
Publisher: name: figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: Detailed materials and methods. (DOCX 8979 kb)
title: Pre-classified documentation sheet including notes about the rise of Arab nationalism in the beginning of the 20th century (verso)
title: بطاقة وثائقية مبوّبة تتضمّن مذكّرات عن صعود القومية العربية في بداية القرن العاشرين - ظهر
title: Fiche de documentation préclassifiée portant des notes sur la montée du nationalisme arabe au début du XXe siècle (verso)
Creators: name: Seurat, Michel
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2019

description: Notes classified under the theme "Nation"
description: Notes rangées sous le thème "Nation".
description: مذكّرات في اللغة الفرنسية تتعلق بموضوع "الوطن"
Social Policy in Australia: What Future for the Welfare State? Proceedings of National Social Policy Conference, Sydney, 5-7 July 1989, Volume 6: Concurrent Sessions, Community Services: Policy and Practice
Creators: name: Graham, Sara
Publisher: name: UNSW Sydney
Year: 1990

description: This report contains papers presented to the National Social Policy Conference held at the University of New South Wales from 5-7 July 1989. The overall theme of the Conference was, 'Social Policy in Australia: What Future for the Welfare State?' The Conference was structured around the following five specific themes: i) The Ideology, Philosophy and Political Environment of Social Policy ii) The Economic Environment of Social Policy iii) Income Maintenance and Income Security iv) Community Resources and Services v) From Policy to Practice Six reports of the conference proceedings were published in the Social Policy Research Centre Reports and Proceedings series with the following numbers and titles: No. 79 Volume 1: Plenary Sessions edited by Peter Saunders and Adam Jamrozik. No. 80 Volume 2: Concurrent Sessions. Contributions form the Social Policy Research Centre. edited by Peter Saunders. No. 81 Volume 3: Concurrent Sessions. The Ideology, Philosophy and Political Environment of Social Policy, edited by Adam Jamrozik. No. 82 Volume 4: Concurrent Sessions. Social Policies in Australia and New Zealand, edited by Russell Ross. No. 83 Volume 5: Concurrent Sessions. Income Maintenance and Income Security, edited by Peter Whiteford. No. 84 Volume 6: Concurrent Sessions. Community Services: Policy and Practice, edited by Sara Graham. The papers in this report address a number of issues that relate to the finance, provision, and administration of community services and what the impact of those services has been. The breadth of topics covered in the report ranging from legal aid and child welfare to public housing and health-related services - illustrates the very important role that community services play in the lives of many Australians, particularly those in the most disadvantaged circumstances.
description: Reports and Proceedings; 84
Disabled Children, Disabling Practices
Creators: name: Rees, Stuart
name: Emerson, Anneke
Publisher: name: UNSW Sydney
Year: 1984
Subjects: Support Services
Children with Disabilities
Family Care
Australia

description: One major thematic focus in the Social Welfare Research Centre has been family care of dependent relatives. To date empirical work has centered on family care of disabled elderly relatives (SWRC Reports and Proceedings Nos. 23 and 35) and this monograph was prepared to see if the caring issues, identified among families with elderly relatives, were similarly prevalent among families with handicapped young children. This research does this and more. Stuart Rees and Anneke Emerson from the Social Work Department at the University of Sydney prepared this monograph as part of a research contract issued by the SWRC. On three occasions over a twelve month period they interviewed 51 families to examine their use of health and welfare services for their severely handicapped young children. In addition they noted factors relating to the financial and non-financial costs involved in the caring situation. They found, not surprisingly, that parents (but especially mothers) have enormous and almost unbearable stresses on them if they attempt to care adequately for their severely handicapped young children. Such stress is compounded by the poorly structured and poorly co-ordinated service systems in health and welfare. The research shows, in addition to internal family pressures that the 'helping professionals' were not always very helping because they were too much tied up in their own professional worlds and that they operated in bureaucratic settings which did not facilitate co-ordinated activity. Rees and Emerson further found that the extra financial cost of caring at home for a severely handicapped child was almost triple the amount of the Handicapped Child's Allowance paid by the Department of Social Security, and in addition that this allowance was made available and administered with very little rationality or consistency. Two points stand out. First, co-operation between medical and non-medical services is inadequate to handle need and second, parents' ability to provide care in the home depends on the usefulness of non-medical services, yet these services take a shabby second place behind medical services, which themselves are not always appropriate in the circumstances. The authors conclude with a number of policy options relating to service organisation and co-ordination, and family support. This is a pioneering piece in an area in which there is virtually no Australian research. As such anyone hoping for a definitive report on issues relating to the care of handicapped children will not have their expectations met here. They will not, however, be disappointed for this study traces the background and provides valuable data on a small sample. In doing so it adds to our store of knowledge, and in the best of research traditions raises questions about directions for future research in this important area.
description: Reports and Proceedings; 37
Diary of Social Legislation and Policy 1981
Creators: name: Davis, Mari
name: McAllister, Margaret
name: Manning, Ian
Publisher: name: UNSW Sydney
Year: 1982
Subjects: Social Policy
Legislative Changes
Commonwealth Government;
Australia

description: This Diary summarises the legislative and administrative changes made in the social policy field during 1981 by the Commonwealth government, and to a lesser extent by the State governments. It provides a ready reference for research workers, and can also be used as a succinct and factual account of policy during the year. Unlike its predecessors, this Diary attempts to cover the main policy changes at a State level in the social policy field. It was not possible to obtain complete coverage for all fields and all States, but it was decided to publish those summaries which were obtained, on the grounds that a beginning must be made. This Diary covers the main areas of social policy apart from education. However, it makes no mention of general economic policy or political events. For these the reader is referred to the 'Diary of Recent Economic Events and policy statements' included in each issue of the Australian Economic Review, to the Diary of Political Events in each issue of Australian Quarterly, and to the 'Broadcasting Chronology' included since 1981 in Media Information Australia.
description: Diary of Social Legislation and Policy; 1981
Measuring the Costs of Living of Australian Families
Creators: name: Manning, Ian
Publisher: name: UNSW Sydney
Year: 1984
Subjects: Australia
Costs of Living
Families

description: Arguments about the construction and application of equivalence scales have been a constant feature of the income security debate in Australia over the past decade. Ian Manning has written this monograph to provide a review of the attempts to derive equivalence scales from Australian data, and to try to indicate some directions for future work. In his words, An equivalence scale gives an estimate of the relative income required, on average, for households with different characteristics to attain the same standard of living. As such it is a precise estimate of a somewhat hazy concept, and the merits and accuracy of different equivalence scales are therefore necessarily contested. Indeed, some would say that the methodological problems in deriving a widely-accepted equivalence scale are so serious that the concept should be abandoned, but unfortunately it will not go away; the concept is fundamental to the measurement of economic inequality, and it also lies at the basis of the table of social security rates.
description: Reports and Proceedings; 43
VANILLYLACETONA PRIMERA AYUDA EN PAÍSES EN DESARROLLO
Creators: name: Dossetti, Anderson
Publisher: name: figshare
Year: 2017
Subjects: subject: 111704 Community Child Health
subject: FOS: Health sciences

description: VANILLYLACETONE AS FIRST AID IN DEVELOPING COUNTRIES

 Doctor Anderson Dossetti

 Miami, Florida 03/11/2016 (Rev. 03/16/2016)

 RESUMEN

 VANILLYLACETONA PRIMERA AYUDA EN PAÍSES EN DESARROLLO La vanillylacetona 4-(HO)C6H3-3-(OCH3)CH2CH2COCH3  soluble 1/50% de alcohol es hallada principalmente en algunas plantas de la familia de las zinguiberáceas. La vanillylacetona juega un papel importante en la oxidación los lípidos al inhibir los fosfolípidos ribosómicos cuando se combina con Fe2+ and Fe3+ catalizando la oxidación lipídica, también juega un papel importante como inhibidor xenobiótico de enterotoxinas producidas y secretadas por organismos bacteriales produciendo reacciones citotóxicas en el organismo invadido. Las enterotoxinas son particularmente peligrosas siendo comúnmente encontradas en países en desarrollo produciendo infecciones gastrointestinales siendo esta la causa principal de mortalidad infantil en estos países. Sin embargo, estudios in vitro han demostrado que la vanillylacetona es capaz de reducir las enterotoxinas y reacciones citotóxicas posiblemente debido a la liberación de catecolamina actuando esta en el desdoblamiento lipídico celular también como de radicales libres y elementos xenobióticos.
Additional file 17 of Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3
Creators: name: Jing, Yipei
name: Jiang, Xueke
name: Lei, Li
name: Peng, Meixi
name: Ren, Jun
name: Xiao, Qiaoling
name: Tao, Yao
name: Tao, Yonghong
name: Huang, Junpeng
name: Wang, Lu
name: Tang, Yuting
name: Yang, Zailin
name: Yang, Zesong
name: Zhang, Ling
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 17 : Figure S12. Screening for the ubiquitin ligase of EGR1. a Network view of the predicted E3 ubiquitin ligase for EGR1. b Recognition motif for the potential E3 ubiquitin ligase MDM2 in the EGR1 sequence.
Social Policy and the Challenges of Social Change, Proceedings of the National Social Policy Conference, Sydney, 5-7 July 1995, Volume 2
Creators: name: Saunders, Peter
name: Shaver, Sheila
Publisher: name: UNSW Sydney
Year: 1995
Subjects: Work
Welfare
Social Inequality
Economic Inequality
Families
Community Services
Poverty

description: This year's conference was divided into broad social policy themes: Work and Welfare; Social and Economic Inequality; Family, the Life Course and the State; Community Services; Citizenship and the Mixed Economy of Welfare; and an Open Section which covered a variety of themes not included in the above categories. This volume of papers from the Conference includes the keynote address, the first of the plenary papers and thirteen contributed papers. There is no connecting theme to the contributed papers which are in alphabetical order by author within each volume.
description: Reports and Proceedings; 123
Modeling environmental impacts and risk under data uncertainties
Creators: name: Kena Zhao
name: Tsan Sheng (Adam) Ng
name: Harn Wei Kua
name: Muchen Tang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: Computational Biology

description: In this article, we propose a methodology to evaluate the risk of environmental and life cycle impacts under data uncertainties that can be applied to a broad range of data availability assumptions. Specifically, we first propose a data uncertainty model that can accommodate scenarios where only a few data points are known, where data histograms are available, or where multiple, inconsistent data sources are present. An impact risk valuation model is then developed, based on the certainty equivalent of an exponential dis-utility function. We show that the evaluation of the impact risk value can be achieved using a closed-form expression and demonstrate an application in a food waste recycling alternatives comparison. We further extend the methodology to construct an impact safety index model that evaluates uncertain impacts using an impact tolerance level. We show that the proposed model is computationally tractable and can be used as an optimization criterion. Computational studies in an example of sustainable building material selection are then used to demonstrate the improvement of the proposed model compared with the standard approach of optimizing average impacts across several statistical criteria.
The anti-apoptotic protein survivin can improve the prognostication of meningioma patients
Creators: name: Winther, Theo
name: Torp, Sverre
Publisher: name: figshare
Year: 2017
Subjects: subject: 110316 Pathology (excl. Oral Pathology)
subject: FOS: Clinical medicine

description: Dataset from the study "The anti-apoptotic protein survivin can improve the prognostication of meningioma patients"
An Effective Semiparametric Estimation Approach for the Sufficient Dimension Reduction Model
Creators: name: Ming-Yueh Huang
name: Chin-Tsang Chiang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: In the exploratory data analysis, the sufficient dimension reduction model has been widely used to characterize the conditional distribution of interest. Different from the existing approaches, our main achievement is to simultaneously estimate two essential elements, basis and structural dimension, of the central subspace and the bandwidth of a kernel distribution estimator through a single estimation criterion. With an appropriate order of kernel function, the proposed estimation procedure can be effectively carried out by starting with a dimension of zero until the first local minimum is reached. Meanwhile, the optimal bandwidth selector is ensured to be a valid tuning parameter for the central subspace estimator. An important advantage of this estimation technique is its flexibility to allow a response to be discrete and some of covariates to be discrete or categorical providing that a certain continuity condition holds. Under very mild assumptions, we further derive the uniform consistency of the introduced optimization function and the consistency of the resulting estimators. Moreover, the asymptotic normality of the central subspace estimator is established with an estimated rather than exact structural dimension. In extensive simulations, the developed approach generally outperforms the competitors. Data from previous studies are also used to illustrate the proposal. On the whole, our methodology is very effective in estimating the central subspace and conditional distribution, highly flexible in adapting diverse types of a response and covariates, and practically feasible in obtaining an asymptotically optimal and valid bandwidth estimator. Supplementary materials for this article are available online.
Additional file 18 of Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3
Creators: name: Jing, Yipei
name: Jiang, Xueke
name: Lei, Li
name: Peng, Meixi
name: Ren, Jun
name: Xiao, Qiaoling
name: Tao, Yao
name: Tao, Yonghong
name: Huang, Junpeng
name: Wang, Lu
name: Tang, Yuting
name: Yang, Zailin
name: Yang, Zesong
name: Zhang, Ling
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 18 : Figure S13. Nuclear HOTAIRM1 promotes cell cycle progression and inhibits apoptosis in leukemia cells through EGR1. a, c Flow cytometry was used to determine and compare the differences in cell cycle progression in differently transfected groups of OCI-AML3 (a) and OCI-AML2 cells (c). b, d Flow cytometry was used to determine and compare differences in apoptosis in differently transfected groups of OCI-AML3 (b) and OCI-AML2 cells (d). The data are presented as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01. n.s. indicates no significant difference.
Migrants and Occupational Health: A Report
Creators: name: Morrissey, Michael
name: Jakubowicz, Andrew
Publisher: name: UNSW Sydney
Year: 1980
Subjects: Migrants
Occupational Health
Australia

description: In its First Main Report (1975) the Commission of Inquiry into Poverty found that about 12% of recently arrived, non-English speaking migrants have incomes below the poverty line after housing costs are considered. It found, furthermore that migrants are more vulnerable as they bear the brunt, in the workplace, of changing economic fortunes. While the great majority of newly arrived migrant families have incomes above the poverty line this has been achieved at a great price, with great efforts being made and great hardship endured. The Commission suggested (though did not substantiate) that periods of economic hardship have a number of long term effects such as higher rates of health problems, mental health problems and accidents, as well as reduced family life and wasted talents. While these effects are suspected there has been little rigorous work in Australia which gathers together and examines the evidence. There have been suggestions that insufficient data on migrant occupational health and safety exists, and that quite a bit of the research which has been done, and which subsequently has become standard in the literature, lacks rigor. This compounded with regular resort to stereotypes built on prejudices has clouded the issues in studies of migrant occupational health and safety. What we do know is that migrants as a group are concentrated in high-risk occupations. In order to better understand the nature and context of the problem, the Social Welfare Research Centre asked the Centre for Multicultural Studies at the University of Wollongong to cast light on the issue by organising a colloquium to be held in Wollongong (the city with the greatest number of at-risk migrant workers) and to review the existing literature as a guide for researchers and practitioners. The colloquium was held in July 1980 and this report provides the guide to the literature. It is not a report which contains original empirical findings, but its great value lies in its detailed and comprehensive review of the state of knowledge about migrant occupational health and safety in Australia.
description: Reports and Proceedings; 3
title: Le siège de Babel, les missions jésuites dans le Grand Chaco (1700-67)
Creators: name: Richard, Nicolas
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022

description: Source: Nicolas, Richard. 2008. « Les chiens, les hommes et les étrangers furieux : archéologie des identités indiennes dans le Chaco boréal ». Thèse de Doctorat en Anthropologie sociale et ethnologie, Paris, France: EHESS - École des Hautes Études en Sciences Sociales. http://www.theses.fr/2008EHES0321.
Aspects of particle cosmology with an emphasis on baryogenesis
Creators: name: GRAHAM ALBERT WHITE
Publisher: name: Monash University
Year: 2017
Subjects: subject: 20203 Particle Physics
subject: FOS: Physical sciences
subject: Cosmology

description: The Universe is made up of 5% visible matter with the other 95% made up of dark energy and dark matter. Therefore from a particle physics point of view we understand a mere 5% of the Universe. Since we do not Understand the origin of the matter-antimatter asymmetry in the visible sector it can be said that from a cosmological point of view we understand precisely 0% of the content of the Universe. As such dialogue between particle physics and cosmology is expected to yield new insights in both fields. I explore this connection with a focus on the origin of the matter-antimatter asymmetry.
Middle Class Welfare in Australia?
Creators: name: Bradbury, Bruce
Publisher: name: UNSW Sydney
Year: 1998
Subjects: Australia
Middle Class
Welfare

description: The main focus of this report is the question, ‘To what extent are welfare transfers and services in Australia directed towards the ‘middle class’’? However, this question makes most sense when understood in the context of the wider debate about whether such middle class welfare is desirable. Consequently, the report commences with a discussion of the role of the state in providing or funding `welfare services' in mixed economy societies like Australia. ‘Welfare’ is defined here to include government support in cash or kind provided to individuals and households. This includes education, health, social security and welfare, housing and community services, as well as the tax expenditures in these areas. The report focuses upon the most important components of these: education, health, and social security, together with superannuation tax expenditures.
description: Reports and Proceedings; 138
title: The Synthesis and Evaluation of 5-Phenyloxazolidines as Potential Cardiovascular Drugs
Creators: name: Wang, Tammy C.
Publisher: name: Old Dominion University
publisherIdentifier: https://ror.org/04zjtrb98
publisherIdentifierScheme: ROR
Year: 1986

description: Drugs such as adrenoceptor antagonists and certain centrally acting agents are known to lower blood pressure and thus serve as clinically useful antihypertensive agents. Norepinephrine 4, a natural ∝-adrenoceptor agonist, is the major agent associated with increased blood pressure in the periphery. Based on a careful structure-activity comparison, a series of substituted oxazolidines, 20, 21, 22 and 23, have been designed as possible antihypertensive candidates. Specifically, 22 and 23 have been synthesized to serve as potential norepinephrine antagonists.

Preliminary evaluation of these compounds indicated that they were not antihypertensive in nature. The more active compound, 23, was subsequently evaluated for its β-agonist properties using agents such as isoproterenol 9 and a suitable S-antagonist, propranolol 40.
The Glu331del mutation in the CYP17A1 gene causes atypical congenital adrenal hyperplasia in a 46,XX female
Creators: name: Lanzolla, Giulia
name: Vancieri, Giuseppe
name: Lanciotti, Silvia
name: Sangiuolo, Federica
name: Menegatti, Elisa
name: Federici, Luca
name: Moretti, Costanzo
name: Brancati, Francesco
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Biology

description: 17α-Hydroxylase deficiency is an uncommon type of congenital adrenal hyperplasia (CAH) caused by mutations in the CYP17A1 gene encoding both 17α-hydroxylase and 17,20-lyase, essential for sex steroids production. Main clinical features include lack of pubertal development, hypertension, and hypokalemia. We report the first case of a 46,XX female homozygote for the p.Glu331del mutation in the CYP17A1 gene showing an atypical clinical presentation. She was evaluated the first time for primary amenorrhea and delayed puberty in the presence of low levels of androgens, 17β-estradiol, serum cortisol, and high levels of progesterone and gonadotropins. After puberty, the patient did not show hypocortisolism and/or hypertension. She started estrogen therapy for pubertal induction, followed by ethinylestradiol/gestodene with clinical and biochemical stability during the follow-up period. At the age of 40 years, she developed hypokalemia and clinical signs of hypocortisolism. Oral corticosteroid treatment was started showing a prompt clinical improvement. Modeling analysis predicted the main outcome of the E331 deletion to impair cytochrome b5 binding, according to a major effect on the enzyme’s lyase activity. These data broaden the molecular and clinical spectrum of CAH caused by 17α-hydroxylase deficiency and adds to current genotype–phenotype correlations.
NiFe2O4@SiO2–PPA Nanoparticle: A Green Nanocatalyst for the Synthesis of β-Acetamido Ketones
Creators: name: Khojastehnezhad, Amir
name: Moeinpour, Farid
name: Javid, Ali
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: In this work, silica coated magnetic nanoparticles of modified polyphosphoric acid (NiFe2O4@SiO2–PPA deigned as NFS–PPA) represent as a reusable and green catalyst for one-pot four-component synthesis of β-acetamido ketones at room temperature under solvent-free conditions. This catalyst was synthesized and characterized by X-ray diffractions, transmission electron microscopy, scanning electron microscopy and vibrating sample magnetometry. The magnetic catalyst can be easily removed by a simple magnet and reused up to five times without any loss of its high catalytic activity. In addition to facility, this protocol enhances product purity and promises economic and also environmental profits.
title: Uff Dr Hochzittsreis
Creators: name: Kettner, Charles F.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022

description: TEI version for play in Alsatian. Play subtitle: Luschtspiel in 1 Akt im els. Dialekt
Social Policy for the 21st Century: Justice and Responsibility, Proceedings of the National Social Policy Conference, Sydney, 21-23 July 1999, Volume 1
Creators: name: Shaver, Sheila
name: Saunders, Peter
Publisher: name: UNSW Sydney
Year: 1999
Subjects: Australia
Poverty
Homeless
Social Capital
Income Distribution

description: At the century's end, Australians face a global environment fraught with uncertainty. Changes in taxation, employment, the financial relationships between the Commonwealth and the States and welfare reform are on the domestic agenda. The conference theme, Social Policy for the 21st Century: Justice and Responsibility, invites reflection on the policies, the means to fund them, and the kinds of delivery mechanisms that will most effectively contribute to the wellbeing of all Australians in the next century. The Keynote and Plenary addresses evaluate the state and direction of social policy developments on the eve of a new century. Jill Roe brought an historian's eye to past and present developments, in order to assess the prospects for the future trends and priorities. Peter Townsend took up the theme of social exclusion and social polarisation, putting these in the context of national and international policy developments. Anne Marie Guillemard looked at changes in work in later life, and the challenges these pose for employment and employers.
description: Reports and Proceedings; 141
The effect of different progestogens on sleep in postmenopausal women: a randomized trial
Creators: name: Ekachai Leeangkoonsathian
name: Tawiwan Pantasri
name: Somsak Chaovisitseree
name: Nuntana Morakot
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background: While progesterone affects sleep, different types of it might affect sleep differently. Methods: One hundred Thai women, who complained of insomnia, visited the Menopause Clinic at Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand from February 2014 to March 2015, and were divided randomly into two groups. Both groups received daily hormonal treatment that included estradiol valerate (progynova) at 1 mg. The first group also received dydrogesterone (duphaston®) at 10 mg and the second group micronized progesterone (utrogestran®) at 100 mg. The clinical symptoms and Pittsburgh Sleep Quality Index (PSQI) were recorded for three consecutive months after treatment. This study was registered with clinicaltrial.gov (code number NCT02086032). Results: Sleep quality improved in both groups (10.52 ± 4.27 to 4.91 ± 3.15 in the dydrogesterone group and 10.16 ± 3.60 to 6.27 ± 3.04 in the micronized progesterone group, p value 0.08). Women in the micronized progesterone group had fewer overall side effects than those in the dydrogesterone group. Conclusion: Sleep quality of peri-postmenopausal women with insomnia improved dramatically after the first month of hormonal treatment. However, more participating patients are necessary to ascertain the differences in sleep quality from dydrogesterone and micronized progesterone treatment.
Additional file 3 of ZmCCT regulates photoperiod-dependent flowering and response to stresses in maize
Creators: name: Su, Huihui
name: Liang, Jiachen
name: Abou-Elwafa, Salah Fatouh
name: Cheng, Haiyang
name: Dou, Dandan
name: Ren, Zhenzhen
name: Xie, Jiarong
name: Chen, Zhihui
name: Gao, Fengran
name: Ku, Lixia
name: Chen, Yanhui
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 3.
Modeling Environmental Impacts and Risk under Data Uncertainties
Creators: name: Kena Zhao
name: Ng, Tsan Sheng Adam
name: Harn Wei Kua
name: Muchen Tang
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: In this work, we propose a methodology to evaluate the risk of environmental and life cycle impacts under data uncertainties which can be applied to a broad range of data availability assumptions. Specifically, we first propose a data uncertainty model that can accommodate scenarios when only a few data points are known, when data histograms are available, or when multiple, inconsistent data sources are present. An impact risk valuation model is then developed based on the certainty equivalent of exponential disutility function. We show that the evaluation of the impact risk value can be achieved using a closed-form expression, and demonstrate an application in the food waste recycling alternatives comparison. We further extend the methodology to construct an impact safety index model that evaluates uncertain impacts using an impact tolerance level. We show that the proposed model is computationally tractable and can be used as an optimization criterion. Computational studies in an example of sustainable building material selection are then used to demonstrate the improvement of the proposed model compared with a standard approach of optimizing average impacts across several statistical criteria. Supplementary materials are available for this article at the publishers online edition of IISE.
Supermarket Shopping and The Food Retail Environment among SNAP Participants
Creators: name: Schwartz, Gabriel
name: Grindal, Todd
name: Parke Wilde
name: Klerman, Jacob
name: Bartlett, Susan
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Neuroscience
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Computational Biology

description: Much of the research on food deserts has focused on the relationship between the food retail environment and nutrition and health outcomes. Intermediary differences in food shopping patterns are often implicitly assumed to drive these relationships (environment hypothetically affects shopping, which hypothetically affects consumption). Research is limited, though, on whether these food shopping discrepancies exist. This article investigates whether a number of food shopping outcomes and the food retail environment are in fact associated and in which kinds of neighborhoods, using the Electronic Benefit Transfer (EBT) records of over 40 000 households receiving Supplemental Nutrition Assistance Program (SNAP) benefits in western Massachusetts. In some, though not all, food retail environments, we find a small but statistically significant negative association between continuous distance and both the percentage of SNAP redemptions spent at supermarkets and the number of benefit-spending trips taken to supermarkets. Nonetheless, SNAP households located in neighborhoods with what would be considered poor access to supermarkets still spent, on average, more than 75% of their redemptions at these retailers, only 5 percentage points lower than households located one block from a supermarket. These results suggest that SNAP participants’ inability to reach healthy food retailers is at most a minor driver of geographic disparities in nutrition and health outcomes.
Additional file 19 of Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3
Creators: name: Jing, Yipei
name: Jiang, Xueke
name: Lei, Li
name: Peng, Meixi
name: Ren, Jun
name: Xiao, Qiaoling
name: Tao, Yao
name: Tao, Yonghong
name: Huang, Junpeng
name: Wang, Lu
name: Tang, Yuting
name: Yang, Zailin
name: Yang, Zesong
name: Zhang, Ling
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 19 : Figure S14. Cytoplasmic HOTAIRM1 promotes leukemia cell autophagy and proliferation through ULK3. a, c Western blot analysis of LC3-II, p62 and ULK3 levels in HOTAIRM1-silenced OCI-AML3 cells following ULK3 overexpression (a) and HOTAIRM1-overexpressed OCI-AML2 cells following ULK3 knockdown (c). b, d CCK-8 assays were used to analyze cell proliferation in transfected OCI-AML3 (b) and OCI-AML2 cells (d). The data are presented as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001. n.s. indicates no significant difference.
Black Children : White Welfare? Aboriginal Child Welfare Law and Policy in New South Wales
Creators: name: Chisholm, Richard
Publisher: name: UNSW Sydney
Year: 1985
Subjects: Aboriginal Child Welfare
New South Wales

description: This is a study of Aboriginal child welfare. The main focus is on New South Wales, but the issues confront people in all parts of Australia. Is there such a thing as Aboriginal child welfare? Should there be? The initial response of many people might be that laws and policies should not in any way distinguish between Aboriginal and other children. Laws and policies which make any such distinction between children of different races seem contrary to current notions of equality. Should we not be striving towards a child welfare system in which it makes no difference whether a child is black or white? The purpose of this study is to show that whether this is the right goal for child welfare is a remarkably complex question. Many Aboriginal people believe that it is not. They yearn for a future in which they, as Aboriginal people, have control over their destiny and the right to pass on to their children what it is to be Aboriginal. Many have bitter memories of attempts by white people to “assimilate” them, and of the use of child welfare laws to take their children away; away from their homes and communities, and often more than that away from their identity as Aboriginal people. For them, laws and policies based on simple notions of equality and non-discrimination mean a society in which the original invasion and theft of their land become legitimated through the gradual disappearance of any identifiable Aboriginal identity. Aboriginal concerns about their children and the child welfare system, as much as about land rights, touch on wider claims to justice. This study, then, attempts to consider Aboriginal child welfare in the light of these wider issues.
description: Reports and Proceedings; 52
Additional file 2: of Comparative genomic analysis of 127 Escherichia coli strains isolated from domestic animals with diarrhea in China
Creators: name: Tang, Fang
name: Wang, Juanfang
name: Li, Dezhi
name: Gao, Song
name: Ren, Jianluan
name: Ma, Liqing
name: Liu, Fei
name: Zhuge, Xiangkai
name: Yan, Genqiang
name: Lu, Yan
name: Dai, Jianjun
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Figure S1. Presence of antibiotic-resistance genes in E. coli isolates. Red and green bars on the x-axis represent a geographical location in southeast and northwest China, respectively. The bright red and dark blue regions represent the presence or absence of genes in a particular isolate, respectively. This figure shows that significantly more antibiotic resistance genes were found in isolates from southeast than northwest China. (PDF 46 kb)
Высшее образование сегодня,Выпуск 5 2021
Creators: name: Автономная некоммерческая организация высшего образования «Российский новый университет»
Publisher: name: Автономная некоммерческая организация высшего образования «Российский новый университет»
Year: 2021

description: Высшее образование сегодня,Выпуск 5 2021
Interzonal airflow rates for use in near-field far-field workplace concentration modeling
Creators: name: Keil, Chris
name: Yuxi Zhao
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Interzonal air flow rates (β) for a workspace above a table were measured in 12 indoor air spaces using an experimental apparatus simulating a vapor release into an occupied near zone. The near field was modeled as a 0.32 m3 rectangular cube volume 0.60 m high above the 0.60 m × 0.90 m table. A total of 74 experimental measurements of β were made. The apparatus consisted of photoionization detectors measuring concentrations of acetone around an evaporating liquid surface with a robot arm simulating worker motion in the near field. The vapor release rate and the resulting concentrations were used in a near-field far-field (NF-FF) model to calculate β. Measures of mixing within the near-field supported the assumption of the NF-FF model that the near field is well-mixed. Measured values of β ranged from 0.4–19 m3/min with an average of 4.8 m3/min. This corresponds to 1.2–59 air changes per minute in the near field and an average of 15 air changes per minute. The values of β were log normally distributed with a geometric mean of 3.4 m3/min and a geometric standard deviation of 2.3. The 95% confidence interval on the geometric mean of β was 2.8–4.2 m3/min. The product of the random air speed in the room and one half of the near-field free surface area was shown to be a good method of determining β. There was a slight correlation seen between room volume and β, but the effect size was small. Room air change rate was not found to be correlated with β. The observed distribution of β will be helpful in selecting values for interzonal airflow rate in NF-FF modeling of worker exposures.
Evaluating polymer degradation with complex mixtures using a simplified surface area method
Creators: name: Steele, Kandace M.
name: Pelham, Todd
name: Phalen, Robert N.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry

description: Chemical-resistant gloves, designed to protect workers from chemical hazards, are made from a variety of polymer materials such as plastic, rubber, and synthetic rubber. One material does not provide protection against all chemicals, thus proper polymer selection is critical. Standardized testing, such as chemical degradation tests, are used to aid in the selection process. The current methods of degradation ratings based on changes in weight or tensile properties can be expensive and data often do not exist for complex chemical mixtures. There are hundreds of thousands of chemical products on the market that do not have chemical resistance data for polymer selection. The method described in this study provides an inexpensive alternative to gravimetric analysis. This method uses surface area change to evaluate degradation of a polymer material. Degradation tests for 5 polymer types against 50 complex mixtures were conducted using both gravimetric and surface area methods. The percent change data were compared between the two methods. The resulting regression line was y = 0.48x + 0.019, in units of percent, and the Pearson correlation coefficient was r = 0.9537 (p ≤ 0.05), which indicated a strong correlation between percent weight change and percent surface area change. On average, the percent change for surface area was about half that of the weight change. Using this information, an equivalent rating system was developed for determining the chemical degradation of polymer gloves using surface area.