cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Rhinolophidae Gray 1825
Creators: name: Burgin, Connor
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Chiroptera
Rhinolophidae

description: Family RHINOLOPHIDAE (HORSESHOE BATS) • Relatively small to medium-sized insectivorous bats with ornate facial growths including horseshoe-shaped plate between mouth and nares and ears without tragus. • 5-16- 5 cm. • Palearctic, Afrotropical, Indo-Malayan, and Australasian Regions. • Deserts, forests, and mountainous areas, mainly tropical but extending into temperate regions to c. 52° N. • 1 genus, 109 species, 199 taxa. • 1 species Critically Endangered, 6 species Endangered, 6 species Vulnerable; none Extinct since 1600.
description: Published as part of Burgin, Connor, 2019, Rhinolophidae, pp. 280-332 in Handbook of the Mammals of the World – Volume 9 Bats, Barcelona :Lynx Edicions on page 260, DOI: 10.5281/zenodo.3748525
Using the Sun to estimate Earth-like planets detection capabilities. V. Parameterizing the impact of solar activity components on radial velocities
Creators: name: Borgniet, Simon
name: Meunier, Nadège
name: Lagrange, Anne-Marie
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Stellar activity induced by active structures (eg, spots, faculae) is known to strongly impact the radial velocity time series. It then limits the detection of small planetary RV signals (eg, an Earth-mass planet in the habitable zone of a solar-like star). In previous papers, we studied the detectability of such planets around the Sun seen as an edge-on star. For that purpose, we computed the RV and photometric variations induced by solar magnetic activity, using all active structures observed over one entire cycle. Our goal is to perform similar studies on stars with different physical and geometrical properties. As a first step, we focus on Sun-like stars seen with various inclinations, and on estimating detection capabilities with forthcoming instruments. To do so, we first parameterize the solar active structures with the most realistic pattern so as to obtain results consistent with the observed ones. We simulate the growth, evolution and decay of solar spots, faculae and network, using parameters and empiric laws derived from solar observations and literature. We generate the corresponding structure lists over a full solar cycle. We then build the resulting spectra and deduce the RV and photometric variations for a `Sun' seen with various inclinations. The produced RV signal takes into account the photometric contribution of structures as well as the attenuation of the convective blueshift. The comparison between our simulated activity pattern and the observed one validates our model. We show that the inclination of the stellar rotation axis has a significant impact on the time series. RV long-term amplitudes as well as short-term jitters are significantly reduced when going from edge-on to pole-on configurations. Assuming spin-orbit alignment, the optimal configuration for planet detection is an inclined star (i~45°).
description: Accepted to Astronomy and Astrophysics on May, 27th 2015. The manuscript includes 22 pages, 20 figures
The impact of per- and polyfluoroalkyl substances on cytotoxicity and global DNA methylation in a placental cell model
Creators: name: Kepper, Stewart
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: Human populations are routinely exposed to per- and polyfluorinated compounds (PFAS), a class of fluorinated compounds characterized by strong carbon-fluorine bonds. Common routes of exposure to PFAS include via drinking water, non-stick pans, carpets and other surfaces treated with PFAS to obtain water repellent properties. PFAS, including perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), are linked to adverse developmental outcomes such as preeclampsia and low infant birth weight. These health outcomes may be mediated by the placenta, an essential developmental organ. Recently, a newly developed PFAS, hexafluoropropylene oxide dimer acid (HFPO-DA), known by the trade name GenX, has been found in high concentrations in municipality drinking water in Wilmington, NC. In light of ongoing human exposure, it is important to determine the effect of PFOS, PFOA and GenX on the placenta. Placental DNA methylation has been linked to adverse neurocognitive outcomes and thus may serve as an indicator of future development. Experiments were first conducted to determine if binding interactions in cell culture serum media could sequester PFAS. JEG3 placental trophoblasts were treated with PFOS, PFOA and GenX in serum (S+) and serum free (S-) media. PFOS alone was found to induce cytotoxicity at a lower dose in S- media than in S+ media. Subsequently, to assess the impact of PFAS on the placental epigenome, DNA methylation levels were measured in response to PFOS, PFOA and GenX exposure in S+ and S- media. LINE-1 DNA methylation was used as a proxy for global methylation. No significant differences from the control were observed (p < 0.05). The results provide evidence that PFOS, PFOA and GenX do not alter LINE-1 DNA methylation in JEG3 trophoblasts. Further research is needed to elucidate the specific impact of PFOS, PFOA and GenX on global and local DNA methylation patterns in the placenta.
MPEC 2024-R226 : 2017 FD1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Modeling non local thermodynamic equilibrium plasma using the Flexible Atomic Code data
Creators: name: Han, Bo
name: Wang, Feilu
name: Salzmann, David
name: Zhao, Gang
Publisher: name: arXiv
Year: 2015
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We present a new code, RCF("Radiative-Collisional code based on FAC"), which is used to simulate steady-state plasmas under non local thermodynamic equilibrium condition, especially photoinization dominated plasmas. RCF takes almost all of the radiative and collisional atomic processes into rate equation to interpret the plasmas systematically. The Flexible Atomic Code (FAC) supplies all the atomic data RCF needed, which insures calculating completeness and consistency of atomic data. With four input parameters relating to the radiation source and target plasma, RCF calculates the population of levels and charge states, as well as potentially emission spectrum. In preliminary application, RCF successfully reproduces the results of a photoionization experiment with reliable atomic data. The effects of the most important atomic processes on the charge state distribution are also discussed.
Investigating Immersion and Migration Decisions: A Cautionary Tale
Creators: name: Modirrousta-Galian, Ariana
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social and Behavioral Sciences
subject: Decision-Making
subject: Migration Decisions
subject: Psychology
subject: FOS: Psychology

description: Background: Agent-based modelling provides an appealing methodological choice for simulating human behaviour and decisions. The currently-dominant approaches based on static transition rates or unverified assumptions are restrictive, and could be enhanced with insights from cognitive experiments on actual decision making. Here, one common concern is that standard surveys or experiments may lack ecological validity, limiting the extent to which research findings can be generalised to real-life settings. For complex, highly emotive decision-making scenarios, such as those related to migration, the typically-used short, methodical survey questions may not appropriately map onto complex real-world decisions of interest. Immersive contexts may offer more accurate representations of reality, potentially enhancing the usefulness of experimental information in multi-disciplinary modelling endeavours. Methods: This pre-registered study of migration decisions, aimed at informing a multi-disciplinary construction of an agent-based model of migration, presents a choice-based interactive fiction game in which players make migration decisions to advance through a story. Participants (N = 1000 Prolific users) were randomly assigned to one of four experimental conditions, three involving different renditions of the game attempting to create immersion, with the last condition presenting the decisions in standard survey format. Results: Although addressing the lack of ecological validity in survey data is important for improving agent-based modelling methodology, the experimental design used to tackle this issue, while responding directly to modelling needs, proved too complex. The created experimental conditions ended up too distinct from each other, involving stimuli that differed in quantity and content. This introduced several unintended and uncontrolled confounds, making it impossible to meaningfully interpret the results of this experiment on its own. Our results act as a cautionary tale for agent-based modellers, highlighting that the modelling needs should not override the principles of experimental design, and provide motivation for more rigorous research on this topic.
Safety and immunogenicity of SARS-CoV-2 mRNA-1273 vaccine in older adults
Creators: name: Denison, M.R.
name: Cross, K.
name: Neuzil, K.M.
name: O'Dell, S.
name: Makhene, M.
name: Widge, A.T.
name: Graham, B.S.
name: Suthar, M.S.
name: Lin, B.C.
name: Leav, B.
name: Beigel, J.H.
name: mRNA-1273 Study Group
name: Floyd, K.
name: Swanson, II, P.A.
name: Makowski, M.
name: Rouphael, N.G.
name: Doria-Rose, N.A.
name: Chappell, J.D.
name: Roberts, P.C.
name: Flach, B.
name: Corbett, K.S.
name: Ledgerwood, J.E.
name: Baric, R.
name: Edara, V.V.
name: Stevens, L.J.
name: Padilla, M.
name: Jackson, L.A.
name: McDermott, A.B.
name: Phadke, V.K.
name: Schmidt, S.D.
name: Pruijssers, A.J.
name: Anderson, E.J.
name: Albert, J.
name: Rostad, C.A.
name: Bennett, H.
name: Buchanan, W.
name: Luke, C.J.
name: Martinez, D.R.
Publisher: name: Massachussetts Medical Society
Year: 2020

description: among the participants who received the 100-μg dose, the GMT in the two age subgroups was 1,183,066 and 3,638,522, respectively. After the second immunization, serum neutralizing activity was detected in all the participants by multiple methods. Binding- and neutralizing-antibody responses appeared to be similar to those previously reported among vaccine recipients between the ages of 18 and 55 years and were above the median of a panel of controls who had donated convalescent serum. The vaccine elicited a strong CD4 cytokine response involving type 1 helper T cells. CONCLUSIONS In this small study involving older adults, adverse events associated with the mRNA-1273 vaccine were mainly mild or moderate. The 100-μg dose induced higher binding- and neutralizing-antibody titers than the 25-μg dose, which supports the use of the 100-μg dose in a phase 3 vaccine trial.
description: BACKGROUND Testing of vaccine candidates to prevent infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an older population is important, since increased incidences of illness and death from coronavirus disease 2019 (Covid-19) have been associated with an older age. METHODS We conducted a phase 1, dose-escalation, open-label trial of a messenger RNA vaccine, mRNA-1273, which encodes the stabilized prefusion SARS-CoV-2 spike protein (S-2P) in healthy adults. The trial was expanded to include 40 older adults, who were stratified according to age (56 to 70 years or ≥71 years). All the participants were assigned sequentially to receive two doses of either 25 μg or 100 μg of vaccine administered 28 days apart. RESULTS Solicited adverse events were predominantly mild or moderate in severity and most frequently included fatigue, chills, headache, myalgia, and pain at the injection site. Such adverse events were dose-dependent and were more common after the second immunization. Binding-antibody responses increased rapidly after the first immunization. By day 57, among the participants who received the 25-μg dose, the anti-S-2P geometric mean titer (GMT) was 323,945 among those between the ages of 56 and 70 years and 1,128,391 among those who were 71 years of age or older
(3595) Molly Garnett
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(3597) Douglas Riley Smith
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Reducing ceiling effects in the Working Alliance Inventory-Rehabilitation Dutch Version
Creators: name: Paap, Davy
name: Schepers, Melvin
name: Dijkstra, Pieter U.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Purpose: To reduce ceiling effects on domain scores (Task, Goal, and Bond) of the Working Alliance Inventory (WAI)-Rehabilitation Dutch Version by changing response scales and using Visual Analogue Scales (VASs). Methods: Clients, who had at least three treatment sessions prior, randomly received one of the three versions of the WAI-Rehabilitation Dutch Version, using items with a balanced Likert scale, Positive-Packed Likert scale or VAS. Primary outcome was percentage of ceiling effects in total- and domain scores, secondary outcomes were construct validity and internal consistency of the three versions. Results: One hundred and seventy-six clients randomly received a set of questionnaires (one of the three versions of the WAI-Rehabilitation Dutch Version, Session Rating Scale (SRS) and Helping Alliance Questionnaire (HAQ)-II); 152 participants (mean age 51.5 ± 16.3, 106 women) returned the questionnaires. No ceiling effects were present in the total scores of all versions. Significantly fewer ceiling effects were found in the VAS-Version (Goal: 8.0%, Bond: 7.7%) compared to the original (Goal: 18.0%, Bond: 29.8%) and Positive-Packed Version (Goal: 27.1%, Bond: 29.8%). Spearman’s correlations between VAS-Version, SRS and HAQ-II ranged 0.747–0.845. Conclusions: Visual Analogue Scales effectively reduced ceiling effects on domain scores of the WAI-Rehabilitation Dutch Version, while maintaining validity.Implications for RehabilitationVisual Analogue Scales effectively reduced ceiling effects on domain scores of the Working Alliance Inventory-Rehabilitation Dutch Version, while maintaining construct validity.The Working Alliance Inventory version with Visual Analogue Scales can be used in rehabilitation. Visual Analogue Scales effectively reduced ceiling effects on domain scores of the Working Alliance Inventory-Rehabilitation Dutch Version, while maintaining construct validity. The Working Alliance Inventory version with Visual Analogue Scales can be used in rehabilitation.
When Should Asymptomatic Persons Be Tested for COVID-19?
Creators: name: Mitchell, Stephanie
name: Miller, Melissa B
name: Mehta, Ninad
name: Hemarajata, Peera
name: Schuetz, Audrey N
name: Campbell, Sheldon
name: Palavecino, Elizabeth
name: Butler-Wu, Susan
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: On August 24, 2020, the Centers for Disease Control and Prevention (CDC) updated its website to highlight that asymptomatic individuals, even those with exposure to a COVID-19 positive contact, do not necessarily need to be tested unless they have medical conditions associated with increased risk of severe illness from COVID-19. The CDC subsequently updated its guidance on September 19, 2020 to support testing of asymptomatic persons, including close contacts of persons with documented SARS-CoV-2 infection. In this editorial, the American Society for Microbiology Clinical and Public Health Microbiology Committee's Subcommittee on Laboratory Practices comments on testing of asymptomatic individuals relative to current medical knowledge of the virus and mitigation measures. Specific points are provided concerning such testing when undertaking contact tracing and routine surveillance. Limitations to consider when testing asymptomatic persons are covered, including the need to prioritize testing of contacts of positive COVID-19 cases. We urge the CDC to consult with primary stakeholders of COVID-19 testing when making such impactful changes in testing guidance.
(3592) Frederick McLachlan
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The Case for Model Street Initiatives in Sustainable Development and Wellbeing Policy
Creators: name: Grierson, Shelley
Publisher: name: figshare
Year: 2023
Subjects: Other built environment and design not elsewhere classified
Health policy
Public policy
Other psychology not elsewhere classified

description: This report aims to highlight the success of the model street initiative framework for addressing inequities of access to proximal, functional outdoor spaces for residents in deprived communities. By demonstrating model street initiatives as a successful model for achieving improved well-being, they may be adopted as a template for more projects around the world to achieve greater coordination and scale. This report investigates how this model is further bolstered by the addition and incorporation of three sustainable development goals (SDGs) in particular, into the framework of the transformation template. These SDGs are SDG 3 (well-being); SDG 10 (inequality); and SDG 11 (human settlement). Greater focus on these SDGs is a common theme of need in areas of disadvantage. Further, outdoor space inequities have serious individual and social implications. Poorer mental health, physical health and social cohesion afflict the disadvantaged. These outcomes in turn, contribute to wider health problems and social issues that strain public resources and funds. Outdoor space inequities straddle a number of different policies including environment, housing, health, community and regeneration. As a result, there is no single focus or ownership of the problem, nor consideration for a multidimensional approach. It is a final recommendation of this report that a single, unified policy be defined to address and prioritise proximal, functional outdoor access to residents. Model street initiatives are recommended to realise the benefits of transformative approaches to under-utilised residential spaces, into spaces that meet the needs of communities. A community-led approach to these model transformations ensures the greatest probability of successful return on investment, improving the short and long-term health disadvantages resulting from space inequities.
Growth and plan for a community: a study of Negro life in Chapel Hill and Carrboro, North Carolina
Creators: name: Freeman, Charles Maddry
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1944
Subjects: North Carolina--Carrboro
North Carolina--Chapel Hill
African American neighborhoods
African Americans

description: This study of the Negro community in and immediately around Chapel Hill and Carrboro, North Carolina, attempts two things: to give a brief history of the development of the community and to suggest a plan for future growth.
(3590) Lilian Rolleston
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The Landau-Lifshitz equation in atomistic models
Creators: name: Ellis, M. O. A.
name: Evans, R. F. L.
name: Ostler, T. A.
name: Barker, J.
name: Atxitia, U.
name: Chubykalo-Fesenko, O.
name: Chantrell, R. W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The Landau-Lifshitz (LL) equation, originally proposed at the macrospin level, is increasingly used in Atomistic Spin Dynamic (ASD) models. The models are based on a spin Hamiltonian featuring atomic spins of fixed length, with the exchange introduced using the Heisenberg formalism. ASD models are proving a powerful approach to the fundamental understanding of ultrafast magnetisation dynamics, including the prediction of the thermally induced magnetisation switching phenomenon in which the magnetisation is reversed using an ultrafast laser pulse in the absence of an externally applied field. The paper outlines the ASD model approach and considers the role and limitations of the LL equation in this context.
description: 9 pages, 1 figure
Imagine No Possessions: Divestment and the Social Bond in the work of Howard Fried, John D. Freyer, and Michael Landy
Creators: name: Barrett, Taylor A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2021

description: In 2014, Howard Fried inventoried his deceased mother’s wardrobe in anticipation of exchanging its contents with a group of strangers. In 2001, John D. Freyer sold over all of his personal possessions on eBay and used these sales as the starting point for social exchanges with those who purchased his objects. Lastly, in 2001, Michael Landy employed twelve Operatives to destroy all 7,227 of his possessions in front of a live audience. In this thesis, I propose that mass divestment of personal possessions serves as the starting point for new object rituals and social bonds between these artists and their participants. Drawing on anthropological theory and material culture studies, and approaches borrowed from consumption studies, I first expose the alternative systems of consumption employed by each artist, ultimately arguing that Fried, Freyer, and Landy suggest a rethinking of the status of objects in consumer culture.
NEIGHBORHOOD STATUS AND ALLOSTATIC LOAD: COUNTERVAILING MECHANISMS AMONG BLACK AMERICANS
Creators: name: DeAngelis, Reed
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2020

description: This study asks whether exposure to interpersonal racism suppresses the health benefits of living in high-status neighborhoods for Black Americans. I use structural equation modeling techniques to analyze biosocial data from a diverse sample of working-age Black adults from Nashville. Consistent with past research, I find that Black residents of disadvantaged and mostly Black neighborhoods initially exhibit increased levels of neuroendocrine stress hormones. However, their peers in privileged White neighborhoods report more chronic exposure to interpersonal racism, and related anticipatory strains, which also predict increased stress hormone levels. After accounting for racism-related stressors, Black residents of higher status neighborhoods exhibit similar stress hormone levels as their disadvantaged peers. Living in underprivileged areas can tax the brain and body. But so, too, can living in high-status communities when individuals are regularly treated with contempt and suspicion by others. The broader substantive and methodological implications of these findings are discussed.
“SHOWING OUT”: AFRICAN AMERICAN CULTURAL FESTIVALS AS SITES OF REWORKING GRIEF FROM HISTORICAL TRAUMA
Creators: name: Peyton, Shyra
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2021

description: Festivals offer a time and place for groups to celebrate and remember their history and culture through exhibits and display, food and fare, arts and crafts demonstrations, and music, dance, and performance. For cultural groups that have endured a painful past, cultural festivals also serve as mechanisms for reminding them of what was lost, what survived and thrived, and what was achieved through perseverance. Scholars, however, have remained slow to capture the social-psychological impact that the festive “showing out” has on African Americans. My thesis research aims to examine the visceral experiences of contemporary African American cultural festivals and to investigate the ways in which the festival site transcends festivity to become a space of healing from the psychological injury wrought by historic trauma. This study of the transformational healing experiences that take place during these events provides a vital new perspective on African American cultural festivals.
Evaluating the Role of Polyunsaturated Fatty Acids as Transcriptional Regulators of Human Acyl-Coenzyme A Synthetase Long Chain Isoform 4 (ACSL4)
Creators: name: Hamilton, Jakob  Skyler
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2021

description: Type 2 diabetes mellitus (T2DM) is characterized by the impairment of glucose-stimulated insulin secretion (GSIS). Across species, GSIS is differentially driven by dietary macronutrients. Omega-6 polyunsaturated fatty acids (PUFAs) not only inhibit GSIS, but also specifically reduce the mRNA and protein expression of acyl-CoA synthetase long chain isoform 4 (ACSL4). ACSLs initiate intracellular lipid metabolism by activating non-esterified fatty acids through their conversion to acyl-CoAs. ACSL4 preferentially activates and channels arachidonate along with its metabolites towards esterification with glycerophospholipids. ACSL4 knockdown, however, results in the accumulation of arachidonate metabolites including unesterified epoxyeicosatrienoic acids (EETs) that impair GSIS. We hypothesized that PUFAs repress ACSL4 mRNA by activating peroxisome proliferator activated receptors (PPARs). After stable transfection with a reporter containing the human ACSL4 promoter, Cos7 cells were exposed to dietary PUFAs and synthetic PPAR agonists. By examining luciferase activity, we show that PUFAs downregulate ACSL4 through PPRE motif-dependent transrepression of PPAR⍺.
(3591) Frank Hardcastle
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Intra-day variability observations and the VLBI structure analysis of quasar S4 0917+624
Creators: name: Liu, X.
name: Mi, L. -G.
name: Liu, J.
name: Cui, L.
name: Song, H. -G.
name: Krichbaum, T. P.
name: Kraus, A.
name: Fuhrmann, L.
name: Marchili, N.
name: Zensus, J. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The IDV observations of S4 0917+624 were carried out monthly, from August 2005 to January 2010, with the Urumqi 25m radio telescope at 4.8 GHz. The quasar S4 0917+624 exhibits only very weak or no IDV during our 4.5 year observing interval. Prior to the year 2000, the source S4 0917+624 was one of the most prominent IDV sources. Our new data indicate that the previous strong IDV has ceased. We analyzed the long-term VLBI structural variability using Gaussian model-fitting. From this we obtained the flux densities and the deconvolved sizes of core and inner-jet components of the source. We studied the properties such as core fraction, angular size, spectral index, and brightness temperature of VLBI core for S4 0917+624, as well as the time delay between 5 and 15 GHz variations, and compared them with the IDV properties of S4 0917+624. The source shows ejection of several jet components that are suspected to have partially reduced the IDV amplitude of S4 0917+624. However, during 2005-2006, the VLBI core size was comparable to the size before the year 2000, but no strong IDV was detected in the period, suggesting that the quenching effect due to source size changes may not be responsible for the lack of strong IDV after the year 2000. The refractive scattering properties for the strong IDV phase of S4 0917+624 before the year 2000 are discussed. The disappearance of strong IDV in S4 0917+624 after the year 2000 is a mystery and cannot be explained via the quenching effect by changes in the observable VLBI structure. However, it may be caused by changes in the interstellar medium, i.e. by interstellar weather, which induces changes in the scintillation pattern on timescales of several years. Further coordinated multi-frequency observations will be required to distinguish between the effect of source-intrinsic variability and changing properties of the interstellar medium.
description: 8 pages, 6 figures, accepted for publication in A&A
(3593) Charles Old
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Torsional oscillations of nonbare strange stars
Creators: name: Mannarelli, Massimo
name: Pagliaroli, Giulia
name: Parisi, Alessandro
name: Pilo, Luigi
name: Tonelli, Francesco
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Strange stars are one of the possible compact stellar objects that can be formed after a supernova collapse. We consider a model of strange star having an inner core in the color-flavor locked phase surmounted by a crystalline color superconducting layer. These two phases constitute the {\it quarksphere}, which we assume to be the largest and heaviest part of the strange star. The next layer consists of standard nuclear matter forming a ionic crust, hovering on the top of the quarksphere and prevented from falling by a strong dipolar electric field. The dipolar electric field arises because quark matter is confined in the quarksphere by the strong interaction, but electrons can leak outside forming a few hundreds Fermi thick electron layer separating the ionic crust from the underlying quark matter. The ionic matter and the crystalline color superconducting matter constitute two electromagnetically coupled crust layers. We study the torsional oscillations of these two layers. Remarkably, we find that if a fraction larger than $10^{-4}$ of the energy of a Vela-like glitch is conveyed to a torsional oscillation, the ionic crust will likely break. The reason is that the very rigid and heavy crystalline color superconducting crust layer will absorb only a small fraction of the glitch energy, leading to a large amplitude torsional oscillation of the ionic crust.
description: 18 pages, 10 figures
title: The Mediating Role of Rumination in the Relation between Basic Psychological Need Frustration and Depressive Symptoms
Creators: name: Heissel, Andreas
name: Pietrek, Anou
name: Kangas, Maria
name: Van der Kaap-Deeder, Jolene
name: Rapp, Michael Armin
Publisher: name: Universitätsverlag Potsdam
Year: 2023
Subjects: subject: 610 Medizin und Gesundheit

description: Research within the framework of Basic Psychological Need Theory (BPNT) finds strong associations between basic need frustration and depressive symptoms. This study examined the role of rumination as an underlying mechanism in the association between basic psychological need frustration and depressive symptoms. A cross-sectional sample of N = 221 adults (55.2% female, mean age = 27.95, range = 18–62, SD = 10.51) completed measures assessing their level of basic psychological need frustration, rumination, and depressive symptoms. Correlational analyses and multiple mediation models were conducted. Brooding partially mediated the relation between need frustration and depressive symptoms. BPNT and Response Styles Theory are compatible and can further advance knowledge about depression vulnerabilities.
description: Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe; 811
Revisiting Actor Programming in C++
Creators: name: Charousset, Dominik
name: Hiesgen, Raphael
name: Schmidt, Thomas C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Programming Languages (cs.PL)
subject: FOS: Computer and information sciences

description: The actor model of computation has gained significant popularity over the last decade. Its high level of abstraction makes it appealing for concurrent applications in parallel and distributed systems. However, designing a real-world actor framework that subsumes full scalability, strong reliability, and high resource efficiency requires many conceptual and algorithmic additives to the original model. In this paper, we report on designing and building CAF, the "C++ Actor Framework". CAF targets at providing a concurrent and distributed native environment for scaling up to very large, high-performance applications, and equally well down to small constrained systems. We present the key specifications and design concepts---in particular a message-transparent architecture, type-safe message interfaces, and pattern matching facilities---that make native actors a viable approach for many robust, elastic, and highly distributed developments. We demonstrate the feasibility of CAF in three scenarios: first for elastic, upscaling environments, second for including heterogeneous hardware like GPGPUs, and third for distributed runtime systems. Extensive performance evaluations indicate ideal runtime behaviour for up to 64 cores at very low memory footprint, or in the presence of GPUs. In these tests, CAF continuously outperforms the competing actor environments Erlang, Charm++, SalsaLite, Scala, ActorFoundry, and even the OpenMPI.
description: 33 pages
Optimizing Throughput and Energy via Fine-Grain Dynamic Voltage Scaling in Elastic Dataflow Systems
Creators: name: Vitkus, Andrew
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2021

description: We propose an approach to jointly optimize throughput and energy consumption in elastic dataflow hardware systems that adapts to changing environmental demands. This is achieved through a novel approach to fine-grain voltage scaling. The system’s processing stages are divided into separate voltage domains with independent and dynamic voltage regulation. We detect local starvation and congestion from local system state measurements to estimate the relationship between local and global throughput and adjust each domains’ voltage to the minimum required by the most restrictive throughput limit. These limits arise from the system’s environments, internal domains that reach their voltage regulators’ limits, and net limits imposed by structures’ latency and throughput requirements. The presence and values of these limits are determined dynamically at runtime without static analysis. The supported dataflows are sequential in FIFOs, parallel in both fork-join and split-merge pairs, and iterative through rings and can be used alone, sequentially, and nested.
D5.5: Reports on the engagement of citizens in (online) scientific courses, and contributions of high school students in scientific research
Creators: name: Licher, Silvan
name: Terzikhan, Natalie
Publisher: name: Zenodo
Year: 2023
Subjects: Responsible Research and Innovation
Formal and informal education

description: This report concerns Deliverable 5.5 of the JoinUs4Health project (grant number 101006518). As leaders of the Work Package (WP) "Formal and informal education", we provide a summary of undertaken activities and reports in relation to the engagement of citizens in (online) scientific courses, and contributions of high school pupils and students in scientific research. In this report, we also reflect and review the impact of these activities on the sustainability of the concept of JoinUs4Health.
Lower limb muscle synergies during walking after stroke: a systematic review
Creators: name: Tamaya Van Criekinge
name: Vermeulen, Jordi
name: Wagemans, Keanu
name: Schröder, Jonas
name: Embrechts, Elissa
name: Truijen, Steven
name: Hallemans, Ann
name: Saeys, Wim
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology

description: Purpose: The aim of this systematic review was to determine the number of muscle synergies and the distribution of muscle weightings in stroke patients during gait. Material and Methods: This review is registered on PROSPERO (number: CRD42018088701) and is written following the PRISMA guidelines. A systematic search was conducted using following databases: PubMed, Web of Science, Naric, Cochrane and PEDro. Methodological quality was assessed by the Newcastle-Ottawa Scale and data extraction (subject characteristics, outcome measures and walking protocols) was performed by two independent researchers. The amount and structure of the muscle synergies were the two main outcome measures. Results: In total, ten studies were included in this review. While four synergies are common in healthy controls, stroke patients often showed less synergies during gait. Synergies were determined by the number of muscles measured which varied greatly between studies. Only Tibialis Anterior, Soleus, Gastrocnemius and Rectus Femoris were assessed in all studies. Conclusions: A consensus regarding the amount and composition of muscle synergies in stroke patients is difficult. The majority observed three to four muscle synergies. The decrease in amount of synergies can be explained by merging of synergies, often seen in hip/knee extensors with plantar flexors and hip/knee extensors with knee flexors.IMPLICATIONS FOR REHABILITATIONMuscle synergy analyses are a powerful tool for assessing and classifying neurological deficits.A decreased amount of muscle synergies is related to impaired motor function.Differences in coordinated muscle activity was seen in the paretic and non-paretic side.Merging was often seen in hip/knee extensors with plantar flexors and hip/knee extensors with knee flexors. Muscle synergy analyses are a powerful tool for assessing and classifying neurological deficits. A decreased amount of muscle synergies is related to impaired motor function. Differences in coordinated muscle activity was seen in the paretic and non-paretic side. Merging was often seen in hip/knee extensors with plantar flexors and hip/knee extensors with knee flexors.
(3589) Stephen Keith Thorburn
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(3585) Nancy Elinor Tennant
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Quantum Logic and Geometric quantization
Creators: name: Camosso, Simone
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mathematical Physics (math-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: 03G12, 03G10, 81P10, 53D50

description: We assume that M is a phase space and H an Hilbert space yielded by a quantization scheme. In this paper we consider the set of all "experimental propositions" of M and we look for a model of quantum logic in relation to the quantization of the base manifold M. In particular we give a new interpretation about previous results of the author in order to build an "asymptotic quantum probability space" for the Hilbert lattice L(H).
A Survey of the State of the Practice for Research Software in the United States
Creators: name: Carver, Jeffrey
name: Weber, Nicholas
name: Ram, Karthik
name: Gesing, Sandra
name: Katz, Daniel S.
Publisher: name: Zenodo
Year: 2022
Subjects: software sustainability

description: Research software is a critical component of contemporary scholarship. Yet, most research software is
 developed and managed in ways that are at odds with its long-term sustainability. This paper presents
 findings from a survey of 1149 researchers, primarily from the United States, about sustainability
 challenges they face in developing and using research software. Some of our key findings include a
 repeated need for more opportunities and time for developers of research software to receive training.
 These training needs cross the software lifecycle and various types of tools. We also identified the
 recurring need for better models of funding research software and for providing credit to those who
 develop the software so they can advance in their careers. The results of this survey will help inform
 future infrastructure and service support for software developers and users, as well as national research
 policy aimed at increasing the sustainability of research software
(3586) Florence Edney
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.