cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Developing Statistical Methods for Incorporating Complexity in Association Studies
Creators: Palmer, Cameron Douglas
Publisher: name: Columbia University
Year: 2017
Subjects: subject: Bioinformatics
subject: FOS: Computer and information sciences
subject: Human genome--Research
subject: Statistics
subject: FOS: Mathematics
subject: Genomics--Statistical methods
subject: Research--Data processing

description: Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with hundreds of human traits. Yet the common variant model tested by traditional GWAS only provides an incomplete explanation for the known genetic heritability of many traits. Many divergent methods have been proposed to address the shortcomings of GWAS, including most notably the extension of association methods into rarer variants through whole exome and whole genome sequencing. GWAS methods feature numerous simplifications designed for feasibility and ease of use, as opposed to statistical rigor. Furthermore, no systematic quantification of the performance of GWAS across all traits exists. Beyond improving the utility of data that already exist, a more thorough understanding of the performance of GWAS on common variants may elucidate flaws not in the method but rather in its implementation, which may pose a continued or growing threat to the utility of rare variant association studies now underway.
      This thesis focuses on systematic evaluation and incremental improvement of GWAS modeling. We collect a rich dataset containing standardized association results from all GWAS conducted on quantitative human traits, finding that while the majority of published significant results in the field do not disclose sufficient information to determine whether the results are actually valid, those that do replicate precisely in concordance with their statistical power when conducted in samples of similar ancestry and reporting accurate per-locus sample sizes. We then look to the inability of effectively all existing association methods to handle missingness in genetic data, and show that adapting missingness theory from statistics can both increase power and provide a flexible framework for extending most existing tools with minimal effort. We finally undertake novel variant association in a schizophrenia cohort from a bottleneck population. We find that the study itself is confounded by nonrandom population sampling and identity-by-descent, manifesting as batch effects correlated with outcome that remain in novel variants after all sample-wide quality control. On the whole, these results emphasize both the past and present utility and reliability of the GWAS model, as well as the extent to which lessons from the GWAS era must inform genetic studies moving forward.
An iron-free nitrogenase? Computational estimation of the ability to bind/activate N2 in manganese and cobalt complexes
Creators: name: Lehene, Maria
Publisher: name: Zenodo
Year: 2024

description: Supporting data set for manuscript An iron-free nitrogenase? Computational estimation of the ability to bind/activate N2 in manganese and cobalt complexes, containing XYZ coordinates of optimized geometries using the B3LYP functional, on Mn and Co complexes of molecular nitrogen (N2).
title: Index Politics
title: Negotiating Competitiveness Agendas in Costa Rica and Nicaragua
titleType: Subtitle
Creators: name: Tornhill, Sofie
Publisher: name: Freie Universität Berlin
Year: 2013
Subjects: subject: competitiveness
subject: labor market flexibilization
subject: the Competition State
subject: class relations
subject: 300 Sozialwissenschaften

description: Yearly published competitiveness indexes make possible immediate comparisons of investment and productivity climates around the globe. Against the backdrop of an increasing linkage between competition, “good governance” and poverty alleviation within development rhetoric and practices, this article places the agenda of competitiveness in the context of political struggle. Based on extensive interviews, I situate the “global” discourse of competitiveness in the diverse conditions of two Central American countries, Costa Rica and Nicaragua, in order to explore articulations and legitimacy claims of business associations and labor organizations respectively in processes of labor market flexibilization and economic change. Focusing on labor–capital and state–market relations, the study contributes to the understanding of how principles of competition are promoted, negotiated and contested within transnational divisions of labor.
Off-shell omega production in proton-proton collisions near threshold
Creators: name: Fuchs, C.
name: Krivoruchenko, M. I.
name: Yadav, H. L.
name: Faessler, Amand
name: Martemyanov, B. V.
name: Shekhter, K.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The omega production in nucleon-nucleon collisions is described through the decay of intermediate nuclear resonances. Close to threshold the pp --> pp omega cross section is dominated by the off-shell production of omega mesons with masses far below the physical omega mass of 782 MeV. A crucial role plays thereby the N^*(1535) resonance. Due to a strong N omega decay mode this resonance leads to off-shell contributions which are in the vicinity of the threshold about one order of magnitude larger than the experimentally measurable contribution from only the omega peak. After a subtraction of the theoretical "background" from off-shell omega production the available data are accurately reproduced over the entire energy range from very close to threshold up to several GeV above threshold. The scenario of a weaker N^*(1535) --> N omega decay mode which is still consistent with electro- and photo-production data is discussed as well. In the latter case the off-shell contributions to the pp --> pp omega cross section are substantially reduced but the description of the experimental cross section is poor above threshold.
description: 12 pages using Revtex, 11 figures, accepted by PRC
title: Advanced diagnostic technologies for Ascochyta blight detection in chickpea
Creators: name: Dyussembayev, Kazbek
Publisher: name: Griffith University
Year: 2023
Subjects: subject: chickpea
subject: Ascochyta blight
subject: disease diagnostics

description: Background: Early diagnosis of plant pathogens is of global interest due to the economic aspects of over-usage of fungicides, as well as their effect on overall grain quality. Consequently, there is a need to develop technology that can provide accurate and timely identification and quantification of plant pathogens. Currently, there are several biosensor applications that involve use of nanotechnology, imaging, mobile phone and even drones for detection of airborne pathogens. This PhD research demonstrates implementation of several proof-of-concept assays, which with further developments towards in-field application, may be useful use in farms, glasshouses and in agricultural nurseries.[...]
Additional file 5 of CXCL13 contributes to chronic pain of a mouse model of CRPS-I via CXCR5-mediated NF-κB activation and pro-inflammatory cytokine production in spinal cord dorsal horn
Creators: name: Wang, Jie
name: Yin, Chengyu
name: Pan, Yushuang
name: Yang, Yunqin
name: Li, Wei
name: Ni, Huadong
name: Liu, Boyu
name: Nie, Huimin
name: Xu, Ruoyao
name: Wei, Huina
name: Zhang, Yunwen
name: Li, Yuanyuan
name: Hu, Qimiao
name: Tai, Yan
name: Shao, Xiaomei
name: Fang, Jianqiao
name: Liu, Boyi
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Additional file 5: Figure S5. Typical signs of astrocytes and microglia upon activation in ipsilateral SCDH of CPIP model mice.Representative pictures showing morphological changes of astrocytesand microgliain ipsilateral SCDH of CPIP model mice upon activation compared with sham group mice.
Editorial: Special issue: Nature-based solutions for reducing disaster risk: What is the evidence?
Creators: name: Sundmeier-Rieux, Karen
name: Galvin, Stephen
name: Nehren, Udo Michael
name: Moos, Christine
name: Vicarelli, Marta
name: Walz, Yvonne
name: Emerton, Lucy
Publisher: name: Elsevier
Year: 2025

description: Nearly two decades ago, the Indian Ocean tsunami created a devastating human tragedy, leaving many questions in its wake as to the role that mangroves may have played in saving lives and livelihoods. Over the following decade, these questions led to the creation of a new field of study: the role of ecosystems in disaster risk reduction, or Eco-DRR. After 2020, Eco-DRR became quasi-synonymous with ‘Nature-based Solutions for disaster risk reduction’, with a few notable differences. What changed as a result of the Indian Ocean tsunami was an increased awareness that ecosystems could - and should - be part of discourse and portfolios of investments in disaster risk reduction (DRR). Over the next two decades, this awareness grew in three phases: 1) 2005–2014: the ‘convincing stage’; 2) 2015–2020: the ‘mainstreaming stage’ 3) 2020: ‘the blue-printing stage’. This collection of articles highlights research on the evidence of the effectiveness of ecosystem approaches for DRR, while addressing the above question: “how to implement”?
title: A aquisição de língua materna e não materna
title: Questões gerais e dados do Português
titleType: Subtitle
Creators: name: (:Unkn) Unknown
Publisher: name: Freie Universität Berlin
Year: 2017
Subjects: subject: 400 Sprache::410 Linguistik

description: The present volume is an introduction to the study of Language Acquisition, especially centered on Portuguese. Even though the different chapters always take Portuguese as a point of departure, a comparative perspective is assumed and Portuguese data is compared to data from other languages, when relevant. This book aims at filling a gap in the literature: an introductory textbook to be used by students of Language Acquisition in Portuguese-speaking countries. The book is composed by chapters authored by several Portuguese and Brazilian researchers and it presents in textbook format a relevant part of the research results obtained during the last decades. The book starts with a general historical presentation of the field. The following chapters explore the acquisition of phonology and syntax and consider the problem of typical and atypical development, as well as linguistic assessment. Bilingualism and L2 acquisition are the topics of two independent chapters. Two final chapters discuss the development of linguistic awareness, in relation to the acquisition of writing.
description: O presente volume é uma introdução ao estudo da aquisição e desenvolvimento linguísticos. Embora especialmente dedicado à aquisição do português como língua materna e não materna, assume uma perspetiva comparada, confrontando dados da aquisição desta língua com os disponíveis para outras línguas do mundo. Surge na sequência da necessidade de um livro de carácter introdutório de apoio à atividade pedagógica nesta área do saber, suprindo uma lacuna há muito sentida por docentes e discentes. Integra capítulos da autoria de vários especialistas portugueses e brasileiros, o que permitiu compilar uma parte substancial do trabalho de investigação sobre aquisição do português desenvolvido nas últimas décadas, em formato de texto de divulgação de fácil acesso. Começando com uma panorâmica histórica das questões centrais colocadas, no último século, sobre a aquisição das línguas naturais, o volume explora vários domínios da aquisição (particularmente, a fonologia e a sintaxe) e considera o desenvolvimento típico e atípico, bem como o problema da avaliação linguística. O bilinguismo e a aquisição de uma L2 são o tema de dois capítulos independentes. Finalmente, relaciona-se o desenvolvimento do conhecimento implícito com o do conhecimento metalinguístico e com a aprendizagem da escrita.
Additional file 1: of Thyroid transcription factor-1 as a prognostic indicator for stage IV lung adenocarcinoma with and without EGFR-sensitizing mutations
Creators: name: Park, Ji
name: Jang, Seung
name: Kim, Hwan
name: Kim, Joo-Hee
name: Sunghoon Park
name: Hwang, Yong
name: Ki-Suck Jung
name: Jinwon Seo
name: Lee, Chang
name: Yousang Ko
name: Park, Yong-Bum
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Plant Biology

description: Table S1. Response analysis among 59 patients with TTF-1 positive expression who received cytotoxic chemotherapy as first-line treatment with or without pemetrexed. Table S2. Response analysis among 27 patients with TTF-1 negative expression who received cytotoxic chemotherapy as first-line treatment with or without pemetrexed. Table S3. Cox proportional hazard model of overall survival for 89 patients with lung adenocarcinoma harboring wild-type EGFR. Table S4. Case summary of five patients with lung adenocarcinoma harboring mutant-type EGFR and no TTF-1 expression. (DOCX 25 kb)
Restricted Boltzmann Machines for Quantum States with Nonabelian or Anyonic Symmetries
Creators: name: Vieijra, Tom
name: Casert, Corneel
name: Nys, Jannes
name: De Neve, Wesley
name: Haegeman, Jutho
name: Ryckebusch, Jan
name: Verstraete, Frank
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Although artificial neural networks have recently been proven to provide a promising new framework for constructing quantum many-body wave functions, the parameterization of a quantum wavefunction with nonabelian symmetries in terms of a Boltzmann machine inherently leads to biased results due to the basis dependence. We demonstrate that this problem can be overcome by sampling in the basis of irreducible representations instead of spins, for which the corresponding ansatz respects the nonabelian symmetries of the system. We apply our methodology to find the ground states of the one-dimensional antiferromagnetic Heisenberg (AFH) model with spin-half and spin-1 degrees of freedom, and obtain a substantially higher accuracy than when using the $s_z$-basis as input to the neural network. The proposed ansatz can target excited states, which is illustrated by calculating the energy gap of the AFH model. We also generalize the framework to the case of anyonic spin chains.
Replication of Infants’ Early Understandings of Caregiving Relationships Study 1
Creators: name: Steele, Christina M.
name: Thomas, Ashley J.
name: Tatone, Denis
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Developmental Psychology
subject: Social Psychology
subject: Cognitive Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: This is a replication study to re-investigate the findings from the studies described in the pre-registration here: https://osf.io/h3u2c/. In this study, we aim to replicate the findings of our original study in a new sample to confirm the robustness and reliability of the effects observed.
Copestylum isabellina
Creators: name: Rotheray, Graham E.
name: Marcos-García, Maria-Angeles
name: Hancock, Geoff
name: Pérez-Bañón, Celeste
name: Maier, Chris T.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Copestylum
Copestylum isabellina

description: COPESTYLUM ISABELLINA (WILLISTON, 1887)
 Larva and puparium (Fig. 26): Anterior fold with a wide band of spicules. Metathorax with two groups of a few indistinct spicules on the anteroventral margin (Fig. 30). Dorsal vestiture comprising evenly sized setae except for anterodorsal groups of large, broad setae on the mesothorax and metathorax (Fig. 29) and smaller setae on middle transverse bands on abdominal segments 1–2. Abdominal segments 4–6 with second row of crochets inconspicuous and not as developed as on abdominal segments 1–3. Posterior breathing tube red-brown at base, dark brown at apex, below TR tube nodulate, above coriaceous. AP about a third as high to spiky rim as wide at TR (Fig. 69). Pupal spiracles, about as far apart as a pupal spiracle is long and slightly curved in upper third. Openings coating upper half of one side, those at the apex with a short spiky projection (Figs 72, 73).
 Taxonomic notes: Very similar in larval characters to C. posticum from which C. isabellina differs in the pupal spiracles being about as far apart as a spiracle is long and the openings at the apex having a short spiky projection.
 Material examined: 15 larvae USA Arizona, Tucson mountains east of Gates Pass, 1.iii.1965 J. F. Burger ex decaying stems of C. giganteus (Cactaceae) (SI); 1 ♀, one puparium USA Arizona, Yuma Co., Kofz mountains 20.i.1969 J. F. Burger ex decaying stems of C. giganteus (SI) 1 ♂, one puparium USA Arizona, Pima Co., 16 km west of Tucson 14.iii.1979 C. T. M. ex decaying stems of C. giganteus (NMS); 2 ♂, 2 ♀ four puparia USA Arizona, Pima Co., 22.5 km west of Tucson 21.iii.1979 C. T. M. ex rot-pocket in C. giganteus (NMS).
 Previous records: Hubbard & Schwarz (1899) ex C. giganteus; Ryckman & Ames (1953) ex C. giganteus; Maier (1982) ex C. giganteus; Mangan (1984) ex C. giganteus; Myles (1986) ex C. giganteus.
description: Published as part of Rotheray, Graham E., Marcos-García, Maria-Angeles, Hancock, Geoff, Pérez-Bañón, Celeste & Maier, Chris T., 2009, Neotropical Copestylum (Diptera, Syrphidae) breeding in Agavaceae and Cactaceae including seven new species, pp. 697-749 in Zoological Journal of the Linnean Society 156 (4) on page 718, DOI: 10.1111/j.1096-3642.2008.00503.x, http://zenodo.org/record/5443474
Content Reconstruction of Parliamentary Questions - Combining Metadata with an OCR Process
Creators: name: Fitsilis, Fotios
name: Schwemmer, Carsten
name: Saalfeld, Thomas
Publisher: name: figshare
Year: 2021
Subjects: subject: 80306 Open Software
subject: FOS: Computer and information sciences
subject: 180120 Legal Institutions (incl. Courts and Justice Systems)
subject: FOS: Law

description: Paper presented in June 2017 at the 5th International Virtual Conference on Advanced Scientific Results, Žilina, Slovakia
The complete set of ground states of the ferromagnetic XXZ chains
Creators: name: Koma, Tohru
name: Nachtergaele, Bruno
Publisher: name: arXiv
Year: 1997
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We show that the well-known translation invariant ground states and the recently discovered kink and antikink ground states are the complete set of pure infinite-volume ground states (in the sense of local stability) of the spin-S ferromagnetic XXZ chains with Hamiltonian H=-sum_x [ S^1_x S^1_{x+1} + S^2_x S^2_{x+1} + Delta S^3_x S^3_{x+1} ], for all Delta >1, and all S=1/2,1,3/2,.... For the isotropic model (Delta =1) we show that all ground states are translation invariant. For the proof of these statements we propose a strategy for demonstrating completeness of the list of the pure infinite-volume ground states of a quantum many-body system, of which the present results for the XXX and XXZ chains can be seen as an example. The result for Delta>1 can also be proved by an easy extension to general $S$ of the method used in [T. Matsui, Lett. Math. Phys. 37 (1996) 397] for the spin-1/2 ferromagnetic XXZ chain with $Δ>1$. However, our proof is different and does not rely on the existence of a spectral gap. In particular, it also works to prove absence of non-translationally invariant ground states for the isotropic chains (Delta=1), which have a gapless excitation spectrum. Our results show that, while any small amount of the anisotropy is enough to stabilize the domain walls against the quantum fluctuations, no boundary condition exists that would stabilize a domain wall in the isotropic model (Delta=1).
description: 23 pages (LaTeX), typos corrected, references updated
Copestylum latum
Creators: name: Rotheray, Graham E.
name: Marcos-García, Maria-Angeles
name: Hancock, Geoff
name: Pérez-Bañón, Celeste
name: Maier, Chris T.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Copestylum
Copestylum latum

description: COPESTYLUM LATUM (WIEDEMANN, 1830)
 Larva and puparium: Anterior fold with a narrow band of spicules. Metathorax with two linear groups of distinct spicules on the anteroventral margin and some spicules on the lateral margins. Dorsal vestiture comprising shorter setae in the middle of transverse bands and with anterodorsal groups of large, broad setae on the mesothorax and metathorax. Abdominal segments 4–6 with second row of crochets inconspicuous and not as developed as on abdominal segments 1–3. Posterior breathing tube red-brown at base, dark brown at apex, below TR tube nodulate, above shiny. AP about a third as high to spiky rim as wide at TR. Pupal spiracles about 2¥ as far apart as a pupal spiracle is long and curved in upper third. Openings coating upper half of one side, those at the apex without a lateral projection.
 Taxonomic notes: Most similar to C. macrocephalum from which it differs in the broader, shorter posterior breathing tube which above the TR to the spiky rim is only about a third as long as TR is wide.
 Material examined (CIBIO, NMS): 2 ♂, 1 ♀, two puparia, one larva MEXICO Tehuacán, Puebla Zapotitlán, Salinas, Jardín Botánico 7.vii.1999 E. G. H., M. A. M., G. E. R. ex decaying fallen M. geometrizans; 1 ♂, one puparium MEXICO, Hidalgo, Metztitlán 19.ix.2005.
description: Published as part of Rotheray, Graham E., Marcos-García, Maria-Angeles, Hancock, Geoff, Pérez-Bañón, Celeste & Maier, Chris T., 2009, Neotropical Copestylum (Diptera, Syrphidae) breeding in Agavaceae and Cactaceae including seven new species, pp. 697-749 in Zoological Journal of the Linnean Society 156 (4) on pages 718-719, DOI: 10.1111/j.1096-3642.2008.00503.x, http://zenodo.org/record/5443474
Negative heat capacities and first order phase transitions in nuclei
Creators: name: Moretto, L. G.
name: Elliott, J. B.
name: Phair, L.
name: Wozniak, G. J.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Anomalous negative heat capacities have been claimed as indicators of first order phase transitions in finite systems in general, and fornuclear systems in particular. A thermodynamic approach allowing for all Q value terms is used to evaluate heat capacities in finitevan der Waals fluids and finite lattice systems in the coexistence region. Fictitious large effects and negative heat capacities are observed in lattice systems when periodic boundary conditions are introduced. Small anomalous effects are predicted for small drops and for finite lattice systems. A straightforward application of the analysis to nuclei shows that negative heat capacities cannot be observed for A>60.
description: 5 pages, 5 figures, submitted to Phys. Rev. C
title: 3-D crustal density model of the Sea of Marmara
Creators: name: Gholamrezaie, Ershad
name: Scheck-Wenderoth, Magdalena
name: Bott, Judith
name: Heidbach, Oliver
name: Strecker, Manfred R.
Publisher: name: Universität Potsdam
Year: 2019

description: Abstract. The Sea of Marmara, in northwestern Turkey, is a transition zone where the dextral North Anatolian Fault zone (NAFZ) propagates westward from the Anatolian Plate to the Aegean Sea Plate. The area is of interest in the context of seismic hazard of Istanbul, a metropolitan area with about 15 million inhabitants. Geophysical observations indicate that the crust is heterogeneous beneath the Marmara basin, but a detailed characterization of the crustal heterogeneities is still missing. To assess if and how crustal heterogeneities are related to the NAFZ segmentation below the Sea of Marmara, we develop new crustal-scale 3-D density models which integrate geological and seismological data and that are additionally constrained by 3-D gravity modeling. For the latter, we use two different gravity datasets including global satellite data and local marine gravity observation. Considering the two different datasets and the general non-uniqueness in potential field modeling, we suggest three possible “end-member” solutions that are all consistent with the observed gravity field and illustrate the spectrum of possible solutions. These models indicate that the observed gravitational anomalies originate from significant density heterogeneities within the crust. Two layers of sediments, one syn-kinematic and one pre-kinematic with respect to the Sea of Marmara formation are underlain by a heterogeneous crystalline crust. A felsic upper crystalline crust (average density of 2720 kgm⁻³) and an intermediate to mafic lower crystalline crust (average density of 2890 kgm⁻³) appear to be cross-cut by two large, dome-shaped mafic highdensity bodies (density of 2890 to 3150 kgm⁻³) of considerable thickness above a rather uniform lithospheric mantle (3300 kgm⁻³). The spatial correlation between two major bends of the main Marmara fault and the location of the highdensity bodies suggests that the distribution of lithological heterogeneities within the crust controls the rheological behavior along the NAFZ and, consequently, maybe influences fault segmentation and thus the seismic hazard assessment in the region.
description: Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe, 737
Additional file 10 of CXCL13 contributes to chronic pain of a mouse model of CRPS-I via CXCR5-mediated NF-κB activation and pro-inflammatory cytokine production in spinal cord dorsal horn
Creators: name: Wang, Jie
name: Yin, Chengyu
name: Pan, Yushuang
name: Yang, Yunqin
name: Li, Wei
name: Ni, Huadong
name: Liu, Boyu
name: Nie, Huimin
name: Xu, Ruoyao
name: Wei, Huina
name: Zhang, Yunwen
name: Li, Yuanyuan
name: Hu, Qimiao
name: Tai, Yan
name: Shao, Xiaomei
name: Fang, Jianqiao
name: Liu, Boyi
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Additional file 10: Table S1. Sequences of primers used for qPCR.
Constraining the masses of microlensing black holes and the mass gap with Gaia DR2
Creators: name: Wyrzykowski, Łukasz
name: Mandel, Ilya
Publisher: name: arXiv
Year: 2019
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context: Gravitational microlensing is sensitive to compact-object lenses in the Milky Way, including white dwarfs, neutron stars or black holes, and could potentially probe a wide range of stellar remnant masses. However, the mass of the lens can be determined only in very limited cases, due to missing information on both source and lens distances and their proper motions. Aims: We aim at improving the mass estimates in the annual parallax microlensing events found in the 8 years of OGLE-III observations towards the Galactic Bulge (Wyrzykowski et al. 2016) with the use of Gaia Data Release 2 (DR2). Methods: We use Gaia DR2 data on distances and proper motions of non-blended sources and recompute the masses of lenses in parallax events. We also identify new events in that sample which are likely to have dark lens; the total number of such events is now 18. Results: The derived distribution of masses of dark lenses is consistent with a continuous distribution of stellar remnant masses. A mass gap between neutron-star and black-hole masses in the range between 2 and 5 solar masses is not favoured by our data, unless black holes receive natal-kicks above 20-80 km/s. We present 8 candidates for objects with masses within the putative mass gap, including a spectacular multi-peak parallax event with mass of $2.4^{+1.9}_{-1.3}\ M_\odot$ located just at 600 pc. The absence of an observational mass gap between neutron stars and black holes, or, conversely, the evidence for black hole natal kicks if a mass gap is assumed, can inform future supernova modelling efforts.
description: 12 pages, published as Wyrzykowski&Mandel, 2020, A&A, 636, A20
Unimodal Aggregation for CTC-based Speech Recognition
Creators: Ying Fang
Xiaofei Li
Publisher: name: IEEE Signal Processing Society
Year: 2024

description: This paper works on non-autoregressive automatic speech recognition. A unimodal aggregation (UMA) is proposed to segment and integrate the feature frames that belong to the same text token, and thus to learn better feature representations for text tokens. The frame-wise features and weights are both derived from an encoder. Then, the feature frames with unimodal weights are integrated and further processed by a decoder. Connectionist temporal classification (CTC) loss is applied for training. Compared to the regular CTC, the proposed method learns better feature representations and shortens the sequence length, resulting in lower recognition error and computational complexity. Experiments on three Mandarin datasets show that UMA demonstrates superior or comparable performance to other advanced non-autoregressive methods, such as self-conditioned CTC. Moreover, by integrating self-conditioned CTC into the proposed framework, the performance can be further noticeably improved.
Additional file 5: of Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance
Creators: name: Akyol, Mehmet
name: Alden, Tord
name: Hernan Amartino
name: Ashworth, Jane
name: Belani, Kumar
name: Berger, Kenneth
name: Borgo, Andrea
name: Braunlin, Elizabeth
name: Eto, Yoshikatsu
name: Gold, Jeffrey
name: Jester, Andrea
name: Jones, Simon
name: Karsli, Cengiz
name: Mackenzie, William
name: Marinho, Diane
name: McFadyen, Andrew
name: McGill, Jim
name: Mitchell, John
name: Muenzer, Joseph
name: Torayuki Okuyama
name: Orchard, Paul
name: Stevens, Bob
name: Thomas, Sophie
name: Walker, Robert
name: Wynn, Robert
name: Giugliani, Roberto
name: Harmatz, Paul
name: Hendriksz, Christian
name: Scarpa, Maurizio
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy

description: Modified-Delphi voting Round 2: Full results of the second round of the modified-Delphi voting, which was used to demonstrate consensus of the guidance statements. (DOCX 41 kb)
Scalar ground-state observables in the random phase approximation
Creators: name: Johnson, Calvin W.
name: Stetcu, Ionel
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We calculate the ground-state expectation value of scalar observables in the matrix formulation of the random phase approximation (RPA). Our expression, derived using the quasiboson approximation, is a straightforward generalization of the RPA correlation energy. We test the reliability of our expression by comparing against full diagonalization in 0 h-bar omega shell-model spaces. In general the RPA values are an improvement over mean-field (Hartree-Fock) results, but are not always consistent with shell-model results. We also consider exact symmetries broken in the mean-field state and whether or not they are restored in RPA.
description: 7 pages, 3 figures
Additional file 1: of Patient empowerment in risk management: a mixed-method study to explore mental health professionalsâ perspective
Creators: name: M. Rimondini
name: I. Busch
name: M. Mazzi
name: V. Donisi
name: A. Poli
name: E. Bovolenta
name: F. Moretti
Publisher: name: figshare
Year: 2019
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Sub-categories (strategies and critical issues) divided by thematic area and category. (DOCX 24 kb)
Doi-Hopf Modules over Weak Hopf Algebras
Creators: name: Böhm, Gabriella
Publisher: name: arXiv
Year: 1999
Subjects: subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics

description: The theory of Doi-Hopf modules is generalized to Weak Hopf algebras.
description: 11 pages, LaTeX file
MOESM1 of The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation
Creators: name: Sai-Tim Ho
name: Jin, Rui
name: Cheung, Derek
name: Huang, Jun-Jian
name: Pang-Chui Shaw
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1. Correlation Analysis for Immunofluorescence Images. Degree of colocalization between proteins expressed as Pearsonâ s correlation coefficient of the two immunofluorescence signals.
SIGIRLARDA GEMOTOLOGIK TEKSHIRISH NATIJALARI
Creators: name: Sulaymonov M.A. - (PhD), v.f.b.f.d, katta o'qituvchi Boymirzayev B. - talaba Abdulazizov M. - talaba Samarqand davlat veterinariya meditsinasi, chorvachilik va biotexnologiyalar universiteti
Publisher: name: Zenodo
Year: 2025

description: Orol bo‘yi ekologik holatning salbiy tomonga o‘zgarishi vaunumdor yerlarning me’yordan ortiq darajada sho‘rlanishi oqibatida, tuproq va suvtarkibining o‘zgarishi, oziqabop o‘simliklarda qoramollar organizmi uchun zarurbo‘lgan makro va mikroelementlar yetishmasligini keltirib chiqarmoqda. Ushbuhududlarda parvarishlanayotgan qoramollar orasida yod, kobalt, mis, marganes,temir, rux, fosfor, kalsiy yetishmovchiligi kabi mikroelementozlar oqibatida sog‘insigirlarning alimentar bepushtliklarini ko‘plab uchrashiga sabab bo‘lmoqda.
Thematic action plans
Creators: name: Dorville, Jean-François
name: Guyon, Emyly
name: Dobarro, Lucía
name: Pugliese, Antonella
Publisher: name: Zenodo
Year: 2021
Subjects: ORs
outermost regions
research
innovation
thematic working groups
thematic action plans
research excellence

description: D3.2 sets out the FORWARD Thematic working groups and thematic action plans methodology. A description of the context and the operating mode of the thematic working groups are presented. The eight action plans submitted are presented under the form of table with a short introduction. The document is completed by an analysis of the action plans.
title: CRE-OPT: Systematische Analyse von Multimedikation. Eine Cluster-randomisierte Studie zur Evaluation der kontinuierlichen digitalen Unterstützung unter Einbeziehung von Patientenpräferenzen in den Niederlanden
Creators: name: Bohnen, Jolijn
name: Stoffers, Jelle
name: van der Weijden, Trudy
name: Denig, Petra
name: van den Akker, Marjan
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die regelmäßige systematische Analyse von Medikamenten bei Patienten mit Multimedikation ist eine hoch relevante, allerdings sehr arbeitsintensive Aufgabe. In der CRE-OPT-Studie wird die Effektivität einer leitlinienbasierten kontinuierlichen Software „Clinical Rules[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 53. Kongress für Allgemeinmedizin und Familienmedizin
Hard Rescattering Mechanism in High Energy Photodisintegration of the Light Nuclei
Creators: name: Sargsian, Misak M.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We discuss the high energy photodisintegrataion of light nuclei in which the energy of the absorbed photon is equally shared between two nucleons in the target. For these reactions we investigate the model in which photon absorption by a quark in one nucleon followed by its high momentum transfer interaction with a quark of the other nucleon leads to the production of two nucleons with high relative momentum. We sum the relevant quark rescattering diagrams, and demonstrate that the scattering amplitude can be expressed as a convolution of the large angle NN scattering amplitude, the hard photon-quark interaction vertex and the low-momentum nuclear wave function. Within this model we calculate the cross sections and polarization observables of high energy gamma + d --> pn and gamma + ^3He --> pp + n reactions.
description: 8 pages Latex, 2 eps figures. Contribution to the conference "Exclusive Processes at High Momentum Transfer", held at Jefferson Laboratory May 15-18, 2002
Developing a ‘ubiquitous’ toolkit for modulating ion channel expression in health & disease
Creators: Kanner, Scott Arthur
Publisher: name: Columbia University
Year: 2021
Subjects: subject: Cytology
subject: Neurosciences
subject: FOS: Clinical medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Ubiquitin
subject: Ion channels
subject: Chronic pain
subject: Epilepsy--Pathophysiology
subject: Cystic fibrosis
subject: Arrhythmia--Pathophysiology

description: Protein stability is critical for the proper function of all proteins in the cell. Ubiquitin is a key post-translational modification that serves as a universal regulator of protein turnover and has emerged as a highly sought-after signal for biological inquiry and drug development. Yet the pervasive role of ubiquitin signaling has given rise to the fundamental challenge of selectively manipulating a widespread signal: current pharmacological and genetic tools that target the ubiquitin-proteasome system (UPS) broadly alter cellular proteostasis with confounding side effects. Ion channels are essential proteins that regulate fundamental cellular properties including; electrical activity, fluid homeostasis, muscle contraction, neuronal firing, gastric acidification, and gene expression. Enhanced or reduced ion channel expression represents a pathological signature for a myriad of disease states, from chronic pain to cardiac arrhythmias, epilepsy, and cystic fibrosis. Although ubiquitin represents a critical mediator of ion channel expression, the inability to precisely manipulate ubiquitin modifications in situ has limited mechanistic insight and opportunities for therapeutic intervention. To address this barrier, I developed a novel nanobody-based toolset to selectively – and bidirectionally – manipulate the ubiquitin status and functional expression of target ion channels for basic study and therapeutic rescue.
Copestylum macrocephalum
Creators: name: Rotheray, Graham E.
name: Marcos-García, Maria-Angeles
name: Hancock, Geoff
name: Pérez-Bañón, Celeste
name: Maier, Chris T.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Syrphidae
Copestylum
Copestylum macrocephalum

description: COPESTYLUM MACROCEPHALUM (GIGLO- TOS, 1892)
 Larva and puparium: Anterior fold with a narrow band of spicules. Metathorax with two linear groups of distinct spicules on the anteroventral margin and some spicules on the lateral margins. Dorsal vestiture comprising shorter setae in the middle of transverse bands and with anterodorsal groups of large, broad setae on the mesothorax and metathorax. Abdominal segments 1–3 with three rows of crochets, third row inconspicuous and not as developed as on abdominal segments 4–6. Posterior breathing tube red-brown at base, dark brown at apex, below TR tube nodulate, above shiny. AP about half as high to spiky rim as wide at TR (Figs 68, 70). Pupal spiracles wide apart, about 2.5¥ as far apart as a pupal spiracle is long and curved in upper third. Openings coating upper half of one side, those at the apex without a lateral projection.
 Taxonomic notes: Most similar to C. latum from which it differs in the narrower, longer posterior breathing tube which above the TR to the spiky rim is about half as long as TR is wide.
 Material examined: 2 ♂, 2 ♀, four puparia MEXICO, Oaxaca, Santiago Dominguillo 14.vii.1999 E. G. H., M. A. M., G. E. R. ex Ferocactus latispinus var. spiralis (Haw) Britton and Rose (NMS); 3 ♂, 3 ♀, six puparia MEXICO, Oaxaca, Valerio Trujano 14.vii.1999 E. G. H., M. A. M., G. E. R. ex Pachycereus hollianus (CIBIO); 1 ♂, 1 ♀, two puparia MEXICO Tehuacán, Puebla Zapotitlán, Salinas, Jardín Botánico 7.vii.1999 E. G. H., M. A. M., G. E. R. ex decaying fallen M.geometrizans (HM); one larva MEXICO Tehuacán, Puebla Zapotitlán, El Salado 8.vii.1999 ex F. latispinus var. spiralis (NMS); 1 ♂, 1 ♀, two puparia MEXICO Tehuacán, Puebla Zapotitlán, Plan de Fierro 10.vii.1999 ex decaying fallen M. geometrizans (CIBIO); one puparium, one larva COSTA RICA Alajuela, Arado 6.xii.1999 Y. Cárdenas, no further data; 8 ♂, 14 ♀, 22 puparia MEXICO, Chiapas, Mazapa de Maderos, 850 m, 22–25.vi.2004 M. A. M. and C. P. B. (CIBIO).
description: Published as part of Rotheray, Graham E., Marcos-García, Maria-Angeles, Hancock, Geoff, Pérez-Bañón, Celeste & Maier, Chris T., 2009, Neotropical Copestylum (Diptera, Syrphidae) breeding in Agavaceae and Cactaceae including seven new species, pp. 697-749 in Zoological Journal of the Linnean Society 156 (4) on page 719, DOI: 10.1111/j.1096-3642.2008.00503.x, http://zenodo.org/record/5443474
The total intrinsic curvature of curves in Riemannian surfaces
Creators: name: Mucci, Domenico
name: Saracco, Alberto
Publisher: name: arXiv
Year: 2019
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53A35, 26A45, 49J45

description: We deal with irregular curves contained in smooth, closed, and compact surfaces. For curves with finite total intrinsic curvature, a weak notion of parallel transport of tangent vector fields is well-defined in the Sobolev setting. Also, the angle of the parallel transport is a function with bounded variation, and its total variation is equal to an energy functional that depends on the "tangential" component of the derivative of the tantrix of the curve. We show that the total intrinsic curvature of irregular curves agrees with such an energy functional. By exploiting isometric embeddings, the previous results are then extended to irregular curves contained in Riemannian surfaces. Finally, the relationship with the notion of displacement of a smooth curve is analyzed.
description: 30 pages, 1 figure; v2: published on Rendiconti del Circolo Matematico di Palermo; v3: with Erratum
Topological transition in measurement-induced geometric phases
Creators: name: Gebhart, Valentin
name: Snizhko, Kyrylo
name: Wellens, Thomas
name: Buchleitner, Andreas
name: Romito, Alessandro
name: Gefen, Yuval
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The state of a quantum system, adiabatically driven in a cycle, may acquire a measurable phase depending only on the closed trajectory in parameter space. Such geometric phases are ubiquitous, and also underline the physics of robust topological phenomena such as the quantum Hall effect. Equivalently, a geometric phase may be induced through a cyclic sequence of quantum measurements. We show that the application of a sequence of weak measurements renders the closed trajectories, hence the geometric phase, stochastic. We study the concomitant probability distribution and show that, when varying the measurement strength, the mapping between the measurement sequence and the geometric phase undergoes a topological transition. Our finding may impact measurement-induced control and manipulation of quantum states---a promising approach to quantum information processing. It also has repercussions on understanding the foundations of quantum measurement.
description: 9 pages, 6 figures + 3 pages supplemental material, 2 figures
Additional file 7 of CXCL13 contributes to chronic pain of a mouse model of CRPS-I via CXCR5-mediated NF-κB activation and pro-inflammatory cytokine production in spinal cord dorsal horn
Creators: name: Wang, Jie
name: Yin, Chengyu
name: Pan, Yushuang
name: Yang, Yunqin
name: Li, Wei
name: Ni, Huadong
name: Liu, Boyu
name: Nie, Huimin
name: Xu, Ruoyao
name: Wei, Huina
name: Zhang, Yunwen
name: Li, Yuanyuan
name: Hu, Qimiao
name: Tai, Yan
name: Shao, Xiaomei
name: Fang, Jianqiao
name: Liu, Boyi
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Hematology

description: Additional file 7: Figure S7. Cxcr5−/− mice showed significantly attenuated mechanical allodynia in contralateral hind paw and reduced c-Fos and glial cell activation in contralateral SCDH in CPIP condition.Time course showing 50% PWT changes in contralateral hindpaws of WT and Cxcr5−/− mice after CPIP model establishment.Summary of normalized AUC of the curves in panel A. n = 6 mice/group.Immunostaining of GFAP, Iba-1and c-Fosin contralateral SCDH from WT + sham, WT + CPIP, Cxcr5−/− + sham and Cxcr5−/− + CPIP groups.Summary of GFAP& Iba-1fluorescence intensity and c-Fospositively stained cell number. n = 4–5 mice/group. *p < 0.05, **p < 0.01 vs. WT + sham group; #p < 0.05, ##p < 0.01 vs. WT + CPIP group. Scale bar indicates 50 μm. Two-way ANOVA with repeated measures followed by Tukey’s post hoc test was used for comparisons in panels A. One-way ANOVA followed by Tukey’s post hoc test was used for comparisons in panels B, F, G&H.
Lorentz Boosted NN Potential for Few-Body Systems: Application to the three-nucleon bound state
Creators: name: Kamada, H.
name: Gloeckle, W.
name: Golak, J.
name: Elster, Ch.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A Lorentz boosted two-nucleon potential is introduced in the context of equal time relativistic quantum mechanics. The dynamical input for the boosted nucleon-nucleon (NN) potential is based on realistic NN potentials, which by a suitable scaling of the momenta are transformed into NN potentials belonging to a relativistic two-nucleon Schroedinger equation in the c.m. system. This resulting Lorentz boosted potential is consistent with a previously introduced boosted two-body t-matrix. It is applied in relativistic Faddeev equations for the three-nucleon bound state to calculate the ^3H binding energy. Like in previous calculations the boost effects for the two-body subsystems are repulsive and lower the binding energy.
description: 25 pages, 5 figures
A Bayesian Two-part Hurdle Quantile Regression Model(R Code_Real Citation Counts)
Creators: name: Shahmandi, Marzieh
name: Wilson, Paul
name: Thelwall, Mike
Publisher: name: figshare
Year: 2021
Subjects: subject: Statistics
subject: FOS: Mathematics

description: This file contains the R code for fitting the Bayesian quantile regression and also the Bayesian two-part quantile regression with hurdle at 0 and 3 by considering real citation count data with excess zeros from 7 fields of Scopus. The Scopus fields are Arts and Humanities (all), Literature and Literary Theory, Religious Studies, Visual Arts and Performing Arts, Media Technology, Architecture, and Emergency Nursing. For MCMC computation of the models, the Gibbs sampler (in R2jags package in R) is used.