cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to normal common marmosets
Creators: name: Löschmann, P. A.
name: Smith, L. A.
name: Lange, Klaus W.
name: Jaehnig, P.
name: Jenner, P.
name: Marsden, C. D.
Publisher: name: Universität Regensburg
Year: 1991
Subjects: subject: 150 Psychologie
subject: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/pharmacology
subject: Animals
subject: Apomorphine/pharmacology
subject: Benzazepines/pharmacology
subject: Callithrix
subject: Dopamine Agents/pharmacology
subject: Dopamine Antagonists
subject: Dose-Response Relationship, Drug
subject: Drug Interactions
subject: Ergolines/pharmacology
subject: Female
subject: Male
subject: Motor Activity/drug effects
subject: Quinpirole
subject: Raclopride
subject: Receptors, Dopamine/drug effects
subject: Receptors, Dopamine D1
subject: Receptors, Dopamine D2
subject: Salicylamides/pharmacology
subject: Stereotyped Behavior/drug effects

description: In normal common marmosets administration of the D-1/D-2 agonist apomorphine or the selective D-2 agonist quinpirole caused a dose-dependent increase in motor activity and induced stereotyped behaviour. Both the selective D-2 antagonist raclopride and the selective D-1 antagonist SCH 23390 inhibited normal locomotor activity and induced catalepsy. Quinpirole- and apomorphine-induced motor activity were potently inhibited by pretreatment with raclopride. The effects of quinpirole, but not apomorphine, were weakly inhibited by SCH 23390. The selective D-1 partial agonist SKF 38393 decreased motor activity and did not induce grooming, oral movements or other behaviours. SKF 38393 inhibited motor activity induced by the administration of quinpirole but did not alter apomorphine-induced motor behaviour. Locomotor activity in normal common marmosets appears to be mediated mainly via D-2 systems. In contrast to rodents, administration of SKF 38393 does not induce behavioural activation and there does not appear to be a facilitating effect of D-1 systems on D-2 function in the normal common marmoset. However, the ability of both SKF 38393 and SCH 23390 to inhibit quinpirole locomotor activity suggests some interaction between D-1 and D-2 systems to occur in this species.
Glutamate receptor antagonism: neurotoxicity, anti-akinetic effects, and psychosis
Creators: name: Riederer, Peter
name: Lange, Klaus W.
name: Kornhuber, J.
name: Jellinger, K.
Publisher: name: Universität Regensburg
Year: 1991
Subjects: subject: 150 Psychologie
subject: Animals
subject: Glutamates/toxicity
subject: Glutamic Acid
subject: Humans
subject: Models, Neurological
subject: Models, Psychological
subject: Nerve Degeneration/drug effects
subject: Neurons/physiology
subject: Neurotoxins/toxicity
subject: Psychotic Disorders/physiopathology
subject: Receptors, Glutamate
subject: Receptors, Neurotransmitter/physiology
subject: Schizophrenia/physiopathology

description: There is evidence to suggest that glutamate and other excitatory amino acids play an important role in the regulation of neuronal excitation. Glutamate receptor stimulation leads to a non-physiological increase of intracellular free Ca2+. Disturbed Ca2+ homeostasis and subsequent radical formation may be decisive factors in the pathogenesis of neurodegenerative diseases. Decreased glutamatergic activity appears to contribute to paranoid hallucinatory psychosis in schizophrenia and pharmacotoxic psychosis in Parkinson's disease. It has been suggested that a loss of glutamatergic function causes dopaminergic over-activity. Imbalances of glutamatergic and dopaminergic systems in different brain regions may result in anti-akinetic effects or the occurrence of psychosis. The simplified hypothesis of a glutamatergic-dopaminergic (im)-balance may lead to a better understanding of motor behaviour and psychosis.
description: ISBN des Bandes 3-211-82261-5, Titel " Age-associated neurological diseases", hg. v. Deecke, L.
Brief Victori Hugio
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1589

description: von [Hans Jakob vom Staal]
description: Brief Nr. 213.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Mai 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
Brief Francisco Guilimanno
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1597

description: von Jo[hann] Jac[obus vom] Staal
description: Brief Nr. 189.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Juni 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
Brief Philippo Malleolo
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1602

description: von Jo[hann] Jac[obus vom] Staal
description: Brief Nr. 202.
description: Original, Siegel nur noch in Spuren vorhanden.
description: Wortlaut identisch mit Brief Nr. 202 bis (Zentralbibliothek Solothurn, Sign. ZBs S I 20/2/202 bis).
description: Lateinisch
description: Verzeichnung=Description=Inventaire Mai 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
Brain muscarinic cholinergic receptors in Huntington's disease
Creators: name: Lange, Klaus W.
name: Javoy-Agid, F.
name: Agid, Y.
name: Jenner, P.
name: Marsden, C. D.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 150 Psychologie
subject: Brain Chemistry
subject: Choline O-Acetyltransferase/analysis
subject: Hippocampus/physiopathology
subject: Humans
subject: Huntington Disease/physiopathology
subject: Nerve Tissue Proteins/analysis
subject: Receptors, Muscarinic/analysis
subject: Temporal Lobe/physiopathology

description: Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects. In comparison with controls, reductions in ChAT activity were found in the hippocampus, but not in the temporal cortex in Huntington's disease. Patients with Huntington's disease showed reduced densities of the total number of muscarinic receptors and of M-2 receptors in the hippocampus while the density of M-1 receptors was unaltered. Muscarinic receptor binding was unchanged in the temporal cortex. These results indicate a degeneration in Huntington's disease of the septo-hippocampal cholinergic pathway, but no impairment of the innominato-cortical cholinergic system.
Brief an Th[omas] Hend[el]
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1608

description: von [Hans Jakob vom Staal]
description: Brief Nr. 207.
description: Lateinisch
description: Verzeichnung=Description=Inventaire HAN-Katalogisierungsregeln Mai 2016/August 2022 iho/HBr
Evaluating Characteristic Functions of Character Sheaves at Unipotent Elements
Creators: name: Taylor, Jay
Publisher: name: arXiv
Year: 2014
Subjects: subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: Primary 20C33, Secondary 20G40

description: Assume $\mathbf{G}$ is a connected reductive algebraic group defined over an algebraic closure $\mathbb{K} = \overline{\mathbb{F}}_p$ of the finite field of prime order $p>0$. Furthermore, assume that $F : \mathbf{G} \to \mathbf{G}$ is a Frobenius endomorphism of $\mathbf{G}$. In this article we give a formula for the value of any $F$-stable character sheaf of $\mathbf{G}$ at a unipotent element. This formula is expressed in terms of class functions of $\mathbf{G}^F$ which are supported on a single unipotent class of $\mathbf{G}$. In general these functions are not determined, however we give an expression for these functions under the assumption that $Z(\mathbf{G})$ is connected, $\mathbf{G}/Z(\mathbf{G})$ is simple and $p$ is a good prime for $\mathbf{G}$. In this case our formula is completely explicit.
description: 29 pages. Parts of this article first appeared in arXiv:1306.5882. This is an expanded and generalised of version of what appears there. (v2): 30 pages. Final version post referees report. Referenced work of Digne-Lehrer-Michel who also independently obtained Theorem 7.7
Additional file 1 of Impact of planning organ at risk volume margins and matching method on late gastrointestinal toxicity in moderately hypofractionated IMRT for locally advanced pancreatic ductal adenocarcinoma
Creators: name: Ogawa, Ayaka
name: Yoshimura, Michio
name: Nakamura, Mitsuhiro
name: Adachi, Takanori
name: Iwai, Takahiro
name: Ashida, Ryo
name: Mizowaki, Takashi
Publisher: name: figshare
Year: 2023
Subjects: subject: Biophysics
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1
Data and Workflow to: Three-dimensional buoyant hydraulic fractures: finite volume release (Möri and Lecampion, (2023))
Creators: name: Möri, Andreas
name: Lecampion, Brice
Publisher: name: Zenodo
Year: 2023
Subjects: Hydraulic Fracture
Boundary integral methods
Magma and lava flow
lubrication flow

description: This upload contains the relevant scripts, notebooks, and datasets to reproduce the numerically obtained results of the Journal article "Three-dimensional buoyant hydraulic fractures: finite volume release" by Möri and Lecampion, (2023).
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease
Creators: name: Löschmann, P. A.
name: Lange, Klaus W.
name: Kunow, M.
name: Rettig, K. J.
name: Jähnig, P.
name: Honoré, T.
name: Turski, L.
name: Wachtel, H.
name: Jenner, P.
name: Marsden, C. D.
Publisher: name: Universität Regensburg
Year: 1991
Subjects: subject: 150 Psychologie
subject: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/pharmacology
subject: Analysis of Variance
subject: Animals
subject: Callithrix
subject: Disease Models, Animal
subject: Drug Synergism
subject: Ibotenic Acid/antagonists & inhibitors
subject: Levodopa/pharmacology
subject: Male
subject: Motor Activity/drug effects
subject: Oxidopamine/pharmacology
subject: Parkinson Disease, Secondary/etiology
subject: Piperazines/pharmacology
subject: Quinoxalines/pharmacology
subject: Rats
subject: Rats, Inbred Strains
subject: Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors
subject: Substantia Nigra/drug effects
subject: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

description: Degeneration of dopaminergic nigrostriatal neurons in Parkinson's disease results in an overactivity of excitatory glutamatergic projections from the subthalamic nucleus to the output nuclei of the basal ganglia resulting in rigidity and akinesia. In theory pharmacological blockade of these overactive systems should improve parkinsonian symptomatology. The selective AMPA-antagonist NBQX and the competitive NMDA-antagonist CPP are not effective in animal models of Parkinson's disease when given alone but ameliorate parkinsonian symptomatology and stimulate locomotor activity when co-administered with a threshold dose of L-Dopa. These synergistic effects are seen in the MPTP-treated (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) common marmoset and the rat with unilateral 6-hydroxydopamine (6-OHDA) lesions of the substantia nigra. Therefore competitive NMDA and non-NMDA antagonists may offer a new therapeutic strategy for the treatment of Parkinson's disease.
Equations of motion in scalar-tensor theories of gravity: A covariant multipolar approach
Creators: name: Obukhov, Yuri N.
name: Puetzfeld, Dirk
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We discuss the dynamics of extended test bodies for a large class of scalar-tensor theories of gravitation. A covariant multipolar Mathisson-Papapetrou-Dixon type of approach is used to derive the equations of motion in a systematic way for both Jordan and Einstein formulations of these theories. The results obtained provide the framework to experimentally test scalar-tensor theories by means of extended test bodies.
description: 5 pages, RevTex format
L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction
Creators: name: Lange, Klaus W.
name: Robbins, T. W.
name: Marsden, C. D.
name: James, M.
name: Owen, A. M.
name: Paul, G. M.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 150 Psychologie
subject: Brain Diseases/physiopathology
subject: Cognition Disorders/psychology
subject: Discrimination (Psychology)/drug effects
subject: Female
subject: Frontal Lobe/physiopathology
subject: Humans
subject: Learning/drug effects
subject: Levodopa/therapeutic use
subject: Male
subject: Memory/drug effects
subject: Middle Aged
subject: Parkinson Disease/drug therapy
subject: Psychomotor Performance/drug effects
subject: Substance Withdrawal Syndrome/physiopathology

description: A group of ten patients with idiopathic Parkinson's disease (PD) was tested on a series of automated tests of learning, memory, planning and attention whilst either on or off L-dopa medication. Controlled withdrawal of L-dopa interfered with aspects of performance on three of the tests that had previously been shown to be sensitive to frontal lobe dysfunction; a spatial working memory task, the Tower of London planning test, and a visual discrimination paradigm that also included intra- and extra-dimensional shift tests of selective attention. More specifically, errors were increased in the spatial working memory test, and both the accuracy and latency of thinking were impaired. Thinking time was significantly slowed following L-dopa withdrawal, even though the possible contaminating effects on motor slowing were fully controlled by a yoked control procedure. Nine out of ten patients reached a further stage of the visual discrimination, set-shifting paradigm when on, rather than off, L-dopa medication. Spatial span was also impaired off medication, but there were no effects of L-dopa withdrawal on tests of pattern and spatial recognition memory, simultaneous and delayed matching to sample or visuospatial conditional associative learning. Comparisons with a large control group confirmed previous findings that PD is associated with deficits on the majority of these tests. The results are discussed in terms of the fronto-striatal, dopamine dependent nature of some of the cognitive deficits found in PD, but the apparent dopamine-independent nature of deficits in other aspects of cognitive functioning, notably in tests of visual recognition memory and associative learning.
Brief Martion Licio
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1603

description: von [Hans Jakob vom Staal]
description: Brief Nr. 231, auf der Rückseite befindet sich Nr. 566.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Juni 2016/August 20'22 HAN-Katalogisierungsregeln iho/HBr
Self-organization and phase transition in financial markets with multiple choices
Creators: name: Zhong, Li-Xin
name: Xu, Wen-Juan
name: Huang, Ping
name: Zhong, Chen-Yang
name: Qiu, Tian
Publisher: name: arXiv
Year: 2013
Subjects: subject: Trading and Market Microstructure (q-fin.TR)
subject: Physics and Society (physics.soc-ph)
subject: FOS: Economics and business
subject: FOS: Physical sciences

description: Market confidence is essential for successful investing. By incorporating multi-market into the evolutionary minority game, we investigate the effects of investor beliefs on the evolution of collective behaviors and asset prices. When there exists another investment opportunity, market confidence, including overconfidence and under-confidence, is not always good or bad for investment. The roles of market confidence is closely related to market impact. For low market impact, overconfidence in a particular asset makes an investor become insensitive to losses and a delayed strategy adjustment leads to a decline in wealth, and thereafter, one's runaway from the market. For high market impact, under-confidence in a particular asset makes an investor over-sensitive to losses and one's too frequent strategy adjustment leads to a large fluctuation in asset prices, and thereafter, a decrease in the number of agents. At an intermediate market impact, the phase transition occurs. No matter what the market impact is, an equilibrium between different markets exists, which is reflected in the occurrence of similar price fluctuations in different markets. A theoretical analysis indicates that such an equilibrium results from the coupled effects of strategy updating and shift in investment. The runaway of the agents trading a specific asset will lead to a decline in the asset price volatility and such a decline will be inhibited by the clustering of the strategies. A uniform strategy distribution will lead to a large fluctuation in asset prices and such a fluctuation will be suppressed by the decrease in the number of agents in the market. A functional relationship between the price fluctuations and the numbers of agents is found.
Arabic massive open online courses and teachers in Saudi Arabia: technology, space, gift and entrepreneurship
Creators: name: Alsayegh, Nada
Publisher: name: The University of Edinburgh
Year: 2023
Subjects: Open Online Courses
Massive Open Online Courses
Arabic Open Online Courses
Arabic Massive Open Online Courses
Saudi Arabia
MOOC
MOOC teacher
MOOC teacher experience

description: This thesis critically examines Arabic Massive Open Online Courses (MOOCs) and the MOOC teacher experience by studying MOOCs in the context of Saudi Arabia from a posthumanist and sociomaterial perspective. It considers the materials, digital technologies and social context as active components in forming MOOCs and developing teachers’ identities and practices. Examination of Arabic MOOC platforms and online courses was conducted through visual analysis, interviews with MOOC teachers, and theoretical work on sociomateriality and spatial theory. Through this analysis, these MOOCs were shown to be deeply implicated in Islamic culture and in educational and policy context of Saudi Arabia. The findings highlight the spatial implications of Arabic MOOCs in a cultural context and show new forms of teaching, spaces, and concepts. Specifically, the MOOC project in Saudi Arabia appeared actively engaged in producing new meanings of gift-giving and entrepreneurship. It reframed giving and knowledge-sharing practices in Islamic culture, including zakat of knowledge and waqf, and reconceptualised entrepreneurship in a digital educational context through the formation of entrepreneurial teachers. These different practices and the identities they produced were overlapping and unpredictable and confirmed the dynamic role of materials and digital technology in forming MOOC spaces, in addition to the entanglements of materials and social dimensions in MOOC teaching and MOOC teacher identity formation. These findings add empirical evidence to theoretical claims that MOOCs are not only a technological medium for online education, but also spatially and relationally produced and enacted. This thesis contributes new knowledge in three main areas. First, it challenges the assumption that MOOCs are ‘universal’ or ‘global’ by shedding light on the Arabic MOOCs and presents an alternative evidence-based perspective from an under-represented cultural context. Secondly, it offers a critical examination of MOOCs by adopting a relational approach and considering the material and digital technology in studying teachers’ experiences in Saudi Arabia. Finally, it shows how Arabic MOOCs actively engage in shaping cultural and entrepreneurial spaces in Saudi Arabia. This thesis makes an original contribution to scholarship in digital education, MOOCs and open education, online teaching, sociomaterial and spatial studies and education in the Gulf and Arab region.
Glutamatergic-dopaminergic balance in the brain. Its importance in motor disorders and schizophrenia
Creators: name: Riederer, Peter
name: Lange, Klaus W.
name: Kornhuber, J.
name: Danielczyk, W.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 150 Psychologie
subject: Animals
subject: Brain Chemistry/physiology
subject: Dopamine/physiology
subject: Glutamates/physiology
subject: Glutamic Acid
subject: Humans
subject: Parkinson Disease/metabolism
subject: Schizophrenia/metabolism

description: Dopamine appears to be of less importance in the regulation of psychomotor functions than was previously thought. A central dopaminergic-glutamatergic balance may be important for both akinetic motor disorders and psychosis. In Parkinson's disease glutamate antagonists may counteract central glutamatergic hyperactivity and may be of value as anti-parkinsonian drugs. An increase of dopaminergic activity and/or a reduction of glutamatergic activity may contribute to the development of paranoid hallucinatory psychosis in schizophrenic patients and of pharmacotoxic psychosis in Parkinson's disease. Because of possibly severe side-effects of glutamatergic antagonists and agonists in the treatment of akinesia and psychosis, the development of partial glutamate agonists/antagonists could be an alternative strategy capable of producing antipsychotic or anti-kinetic effects with only mild adverse reaction.
Brief an [Karl Emanuel I., Herzog von Savoyen]
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1603

description: von [Hans Jakob vom Staal]
description: Brief Nr. 221.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Mai 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
Propagating Parameter Uncertainty in Power System Nonlinear Dynamic Simulations Using a Koopman Operator-Based Surrogate Model
Creators: name: Xu, Yijun
name: Netto, Marcos
name: Mili, Lamine
Publisher: name: arXiv
Year: 2023
Subjects: subject: Systems and Control (eess.SY)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: We propose a Koopman operator-based surrogate model for propagating parameter uncertainties in power system nonlinear dynamic simulations. First, we augment the a priori known state-space model by reformulating parameters deemed uncertain as pseudo-state variables. Then, we apply the Koopman operator theory to the resulting state-space model and obtain a linear dynamical system model. This transformation allows us to analyze the evolution of the system dynamics through its Koopman eigenfunctions, eigenvalues, and modes. Of particular importance for this letter, the obtained linear dynamical system is a surrogate that enables the evaluation of parameter uncertainties by simply perturbing the initial conditions of the Koopman eigenfunctions associated with the pseudo-state variables. Simulations carried out on the New England test system reveal the excellent performance of the proposed method in terms of accuracy and computational efficiency.
Neurotoxicity and neuroprotection in Parkinson's disease
Creators: name: Lange, Klaus W.
name: Youdim, M. B.
name: Riederer, Peter
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 150 Psychologie
subject: Antiparkinson Agents/therapeutic use
subject: Glutathione/metabolism
subject: Humans
subject: Iron/metabolism
subject: Melanins/metabolism
subject: Mitochondria/metabolism
subject: Neurotoxins/metabolism
subject: Oxidation-Reduction
subject: Parkinson Disease/metabolism
subject: Selegiline/therapeutic use
subject: Substantia Nigra/metabolism

description: Recent findings of impaired mitochondrial function, altered iron metabolism and increased lipid peroxidation in the substantia nigra in Parkinson's disease emphasize the significance of oxidative stress and free radical formation in the pathogenesis of the disease. Future research will focus on improvements in neuroprotective therapy to prevent or slow the rate of progression of Parkinson's disease. Possible neuroprotective strategies include free radical scavengers, monoamine oxidase-B inhibitors, iron chelators and glutamate antagonists.
description: ISBN des Bandes 3-211-82347-6, Titel "Advances in neuroscience and schizophrenia", hg. v. Tuma, A. H.
Brief Martino Licio
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1602

description: von [Hans Jakob vom Staal]
description: Brief Nr. 229, auf der Rückseite befindet sich Nr. 484.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Juni 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
Maximal incompatibility of locally classical behavior and global causal order in multi-party scenarios
Creators: name: Baumeler, Ämin
name: Feix, Adrien
name: Wolf, Stefan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Quantum theory in a global space-time gives rise to non-local correlations, which cannot be explained causally in a satisfactory way; this motivates the study of theories with reduced global assumptions. Oreshkov, Costa, and Brukner (2012) proposed a framework in which quantum theory is valid locally but where, at the same time, no global space-time, i.e., predefined causal order, is assumed beyond the absence of logical paradoxes. It was shown for the two-party case, however, that a global causal order always emerges in the classical limit. Quite naturally, it has been conjectured that the same also holds in the multi-party setting. We show that counter to this belief, classical correlations locally compatible with classical probability theory exist that allow for deterministic signaling between three or more parties incompatible with any predefined causal order.
description: 8 pages, 4 figures, title changed, improved presentation, contains two examples
Fronto-striatal cognitive deficits at different stages of Parkinson's disease
Creators: name: Owen, A. M.
name: James, M.
name: Leigh, P. N.
name: Summers, B. A.
name: Marsden, C. D.
name: Quinn, N. P.
name: Lange, Klaus W.
name: Robbins, T. W.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 150 Psychologie
subject: Aged
subject: Attention
subject: Brain Diseases/psychology
subject: Cognition Disorders/psychology
subject: Corpus Striatum/physiopathology
subject: Frontal Lobe/physiopathology
subject: Humans
subject: Memory
subject: Middle Aged
subject: Movement
subject: Neuropsychological Tests
subject: Parkinson Disease/psychology

description: Groups of patients with idiopathic Parkinson's disease, either medicated or unmedicated, were compared with matched groups of normal controls on a computerized battery previously shown to be sensitive to frontal lobe dysfunction, including tests of planning, spatial working memory and attentional set-shifting. In a series of problems based on the 'Tower of London' test, medicated patients with Parkinson's disease were shown to be impaired in the amount of time spent thinking about (planning) the solution to each problem. Additionally, an impairment in terms of the accuracy of the solution produced on this test was only evident in those patients with more severe clinical symptoms and was accompanied by deficits in an associated test of spatial short-term memory. Medicated patients with both mild and severe clinical symptoms were also impaired on a related test of spatial working memory. In contrast, a group of patients who were unmedicated and 'early in the course' of the disease were unimpaired in all three of these tests. However, all three Parkinson's disease groups were impaired in the test of attentional set-shifting ability, although unimpaired in a test of pattern recognition which is insensitive to frontal lobe damage. These data are compared with those previously published from a group of young neurosurgical patients with localized excisions of the frontal lobes and are discussed in terms of the specific nature of the cognitive deficit at different stages of Parkinson's disease.
Braneworld setup and embedding in teleparallel gravity
Creators: name: Behboodi, A.
name: Akhshabi, S.
name: Nozari, K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We construct the setup of a five-dimensional braneworld scenario in teleparallel gravity. Both cases of Minkowski and Friedmann-Robertson-Walker branes embedded in Anti de Sitter bulk are studied and the effective 4-D action were studied. 4-dimensional local Lorentz invariance is found to be recovered in both cases. However, due to different junction conditions, the equations governing the 4-D cosmological evolution differ from general relativistic case. Using the results of Ref. [13], we consider a simple inflationary scenario in this setup. The inflation parameters are found to be modified compared to general relativistic case.
description: 21 pages, no figure, Title Changed, Accepted for Publication in Phys. Lett. B
Cognitive performance in multiple system atrophy
Creators: name: Robbins, T. W.
name: James, M.
name: Lange, Klaus W.
name: Owen, A. M.
name: Quinn, N. P.
name: Marsden, C. D.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 150 Psychologie
subject: Adult
subject: Aged
subject: Caudate Nucleus/pathology
subject: Cognition
subject: Cognition Disorders/physiopathology
subject: Dementia/psychology
subject: Female
subject: Humans
subject: Male
subject: Middle Aged
subject: Nervous System Diseases/psychology
subject: Neuropsychological Tests
subject: Parkinson Disease/psychology
subject: Putamen/pathology
subject: Substantia Nigra/pathology

description: The cognitive performance of a group of patients with multiple system atrophy (MSA) of striato-nigral predominance was compared with that of age and IQ matched control subjects, using three tests sensitive to frontal lobe dysfunction and a battery sensitive to memory and learning deficits in Parkinson's disease and dementia of the Alzheimer type. The MSA group showed significant deficits in all three of the tests previously shown to be sensitive to frontal lobe dysfunction. Thus, a significant proportion of patients from the MSA group failed an attentional set-shifting test, specifically at the stage when an extra-dimensional shift was required. They were also impaired in a subject-ordered test of spatial working memory. The MSA group showed deficits mostly confined to measures of speed of thinking, rather than accuracy, on the Tower of London task. These deficits were seen in the absence of consistent impairments in language or visual perception. Moreover, the MSA group showed no significant deficits in tests of spatial and pattern recognition previously shown to be sensitive to patients early in the course of probable Alzheimer's disease and only a few patients exhibited impairment on the Warrington Recognition Memory Test. There were impairments on other tests of visual memory and learning relative to matched controls, but these could not easily be related to fundamental deficits of memory or learning. Thus, on a matching-to-sample task the patients were impaired at simultaneous but not delayed matching to sample, whereas difficulties in a pattern-location learning task were more evident at its initial, easier stages. The MSA group showed no consistent evidence of intellectual deterioration as assessed from their performance on subtests of the Wechsler Adult Intelligence Scale (WAIS) and the National Adult Reading Test (NART). Consideration of individual cases showed that there was some heterogeneity in the pattern of deficits in the MSA group, with one patient showing no impairment, even in the face of considerable physical disability. The results show a distinctive pattern of cognitive deficits, unlike those previously seen using the same tests in patients with Parkinson's and Alzheimer's diseases, and suggesting a prominent frontal-lobe-like component. The implications for concepts of 'subcortical' dementia and 'fronto-striatal' cognitive dysfunction are considered.
title: Personal responsibility and the role of self-identity in adolescents: a female regional Queensland perspective
Creators: name: Watson, Krystal
Publisher: name: University of Southern Queensland
Year: 2021
Subjects: classificationCode: 390406
subject: Gender, sexuality and education
valueUri: https://www.abs.gov.au/statistics/classifications/australian-and-new-zealand-standard-research-classification-anzsrc/latest-release
classificationCode: 520102
subject: Educational psychology
valueUri: https://www.abs.gov.au/statistics/classifications/australian-and-new-zealand-standard-research-classification-anzsrc/latest-release

description: Adolescence and the transition into adulthood present numerous challenges for the individual experiencing it, their peers, and society generally. Personal responsibility has been established as an important consideration of adolescent development as it equips youth to gain greater control over their behaviour, emotions and thinking. In particular, the development of personal responsibility during adolescence remains an important area of research in the fields of psychology and education. What is less known is the relationship between female adolescents’ self-identity and their personal responsibility in a regional Queensland setting. Research shows that adolescence is known as a time of exploration and decision-making. Therefore, it has been proposed by the researcher that a deeper understanding surrounding the personal development of female adolescents in a Queensland regional setting is required, especially as it relates to self-identity and personal responsibility. This study addresses the gap in professional practice and literature surrounding the relationship between self-identity and personal responsibility based on current definitions of the concepts. This thesis presents the findings of an exploratory study investigating female adolescent perspectives of self-identity, personal responsibility, and the possible relationship between them in a regional Queensland all-girls private secondary school context. Primary data was collected using semi-structured focus group interviews. The results confirmed the definitional dimensions of the concepts of self-identity and personal responsibility. Key findings concur with the study’s propositions that self-identity is positively related to and influences personal responsibility. The emerging themes provided deeper understanding and insights into this relationship. However, the relationship is more complex and reciprocal than first understood. Further, the themes emerging from the analysis suggest that rather than a unidirectional relationship between self-identity and personal responsibility, instead influenced each other. Peer relations were found to have a notable influence on the relationship between self-identity and personal responsibility.
How to run a brain bank. A report from the Austro-German brain bank
Creators: name: Gsell, W.
name: Lange, Klaus W.
name: Pfeuffer, R.
name: Heckers, S.
name: Heinsen, H.
name: Senitz, D.
name: Jellinger, K.
name: Ransmayr, G.
name: Wichart, I.
name: Vock, R.
Publisher: name: Universität Regensburg
Year: 1993
Subjects: subject: 150 Psychologie
subject: Austria
subject: Brain
subject: Dissection/methods
subject: Germany
subject: Humans
subject: International Cooperation
subject: Medical History Taking
subject: Specimen Handling/methods
subject: Tissue Banks/organization & administration

description: The sophisticated analysis of and growing information on the human brain requires that acquisition, dissection, storage and distribution of rare material are managed in a professional way. In this publication we present the concept and practice of our brain bank. Both brain tissue and information are handled by standardized procedures and flow in parallel from pathology to neuropathology and neurochemistry. Data concerning brain material are updated with clinical information gained by standardized procedures.
description: ISBN des Bandes: 3-211-82426-X , Titel "How to run a brain bank", hg. v.Cruz-Sánchez, Felix F.
Matrix product operators and states: NP-hardness and undecidability
Creators: name: Kliesch, M.
name: Gross, D.
name: Eisert, J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Tensor network states constitute an important variational set of quantum states for numerical studies of strongly correlated systems in condensed-matter physics, as well as in mathematical physics. This is specifically true for finitely correlated states or matrix-product operators, designed to capture mixed states of one-dimensional quantum systems. It is a well-known open problem to find an efficient algorithm that decides whether a given matrix-product operator actually represents a physical state that in particular has no negative eigenvalues. We address and answer this question by showing that the problem is provably undecidable in the thermodynamic limit and that the bounded version of the problem is NP-hard in the system size. Furthermore, we discuss numerous connections between tensor network methods and (seemingly) different concepts treated before in the literature, such as hidden Markov models and tensor trains.
description: 7 pages, 2 figures; published version with improved presentation
Iron, copper, zinc, magnesium, and calcium in postmortem brain tissue from schizophrenic patients
Creators: name: Kornhuber, J.
name: Lange, Klaus W.
name: Kruzik, P.
name: Rausch, W. D.
name: Gabriel, E.
name: Jellinger, K.
name: Riederer, P.
Publisher: name: Universität Regensburg
Year: 1994
Subjects: subject: 150 Psychologie
subject: Adult
subject: Aged
subject: Aged, 80 and over
subject: Brain Chemistry
subject: Calcium/analysis
subject: Copper/analysis
subject: Female
subject: Humans
subject: Iron/analysis
subject: Magnesium/analysis
subject: Male
subject: Metals/analysis
subject: Middle Aged
subject: Schizophrenia/metabolism
subject: Zinc/analysis

description: The regional distribution of iron, copper, zinc, magnesium, and calcium in postmortem brain of schizophrenic patients was compared with that of matched controls. In none of the brain regions investigated (caudate nucleus, hippocampus, amygdala, cortex, corpus mamillare, gyrus cinguli, and hypothalamus) were significant differences observed between these two groups. In the total group, region-specific differences were found for iron, copper, zinc, and calcium, but not for magnesium. Gender differences were observed only for zinc. There was no correlation between a neuroleptic-free period before death and the content of any of the metals investigated, except for a positive correlation between copper in the hippocampus and a neuroleptic-free period. The results of the present study suggest that there are no profound differences in the content of iron, copper, zinc, magnesium, and calcium in postmortem brains between controls and schizophrenic patients.
Brief an Fr[ancisco] Guilimanno
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1601

description: von [Hans Jakob vom Staal]
description: Brief Nr. 197.
description: Lateinisch
description: Verzeichnung=Description=Inventaire HAN-Katalogisierungsregeln Juni 2016/August 2022 iho/HBr
Apology of Timothy the Patriarch before the Caliph Mahdi
Creators: name: Mingana, Alphonse
Publisher: name: No Publisher Supplied
Year: 2013

description: Part of Alphonse Mingana’s Woodbrooke Studies: Christian Documents in Syriac, Arabic, and Garshuni, edited and translated with a critical apparatus, of which the present book is volume 2, The Apology of Timothy the Patriarch before the Caliph Mahdi is accompanied in this volume by The Lament of the Virgin and The Martyrdom of Pilate. These three texts demonstrate the variety found in Mingana’s extraordinary collection. The namesake of the volume, Timothy’s apology for Christianity, is an eighth-century manuscript and one of the earliest documents concerning Christianity’s relationship with Islam. In it the “Nestorian” Patriarch Timothy I (780-823) presents his case for his faith to the third Abbasid Caliph Mahdi. The other two documents share a common Egyptian origin and Garshuni epigraphy. Neither The Lament of the Virgin nor The Martyrdom of Pilate claim a great antiquity and both works are pseudepigraphical. Mary’s lament, in the former work, is her sadness at the empty tomb, a piece in which she is conflated with Mary Magdalene. The latter piece presents Pontius Pilate as a saint and lays out his spiritual accomplishments that are crowned by his martyrdom. The texts are presented in their original languages as well as in English.Alphonse Mingana (1878-1937) was an educator at the Chaldean Seminary in Iraq. He was also a priest in the Assyrian tradition and a collector of ancient manuscripts. He is renowned for his Mingana Collection, a set of nearly 3000 early Syrian and Arabic documents which he acquired and preserved.  Mingana eventually immigrated to England, where he spent 17 years in Manchester to continue his work on Oriental Studies.
Brief Th[omæ] Heningio
Creators: name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1599

description: von [Hans Jakob vom Staal]
description: Brief Nr. 209, auf der Rückseite befindet sich Nr. 433.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Mai 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
title: Hazards of pesticides to bees 12th International Symposium of the ICP-PR Bee Protection Group, 15. - 17. September 2014, Ghent (Belgium) - Proceedings - -
Creators: name: Oomen, Pieter A.
name: Pistorius, Jens
Publisher: name: Julius Kühn-Institut
Year: 2015

description: Julius-Kühn-Archiv 450
Altered muscarinic and nicotinic receptor densities in cortical and subcortical brain regions in Parkinson's disease
Creators: name: Lange, Klaus W.
name: Wells, F. R.
name: Jenner, P.
name: Marsden, C. D.
Publisher: name: Universität Regensburg
Year: 1993
Subjects: subject: 150 Psychologie
subject: Brain/metabolism
subject: Cerebral Cortex/metabolism
subject: Choline O-Acetyltransferase/metabolism
subject: Humans
subject: Parkinson Disease/metabolism
subject: Receptors, Muscarinic/metabolism
subject: Receptors, Nicotinic/metabolism
subject: Tissue Distribution

description: Muscarinic and nicotinic cholinergic receptors and choline acetyltransferase activity were studied in postmortem brain tissue from patients with histopathologically confirmed Parkinson's disease and matched control subjects. Using washed membrane homogenates from the frontal cortex, hippocampus, caudate nucleus, and putamen, saturation analysis of specific receptor binding was performed for the total number of muscarinic receptors with [3H]quinuclidinyl benzilate, for muscarinic M1 receptors with [3H]pirenzepine, for muscarinic M2 receptors with [3H]oxotremorine-M, and for nicotinic receptors with (-)-[3H]nicotine. In comparison with control tissues, choline acetyl-transferase activity was reduced in the frontal cortex and hippocampus and unchanged in the caudate nucleus and putamen of parkinsonian patients. In Parkinson's disease the maximal binding site density for [3H]quinuclidinyl benzilate was increased in the frontal cortex and unaltered in the hippocampus, caudate nucleus, and putamen. Specific [3H]pirenzepine binding was increased in the frontal cortex, unaltered in the hippocampus, and decreased in the caudate nucleus and putamen. In parkinsonian patients Bmax values for specific [3H]oxotremorine-M binding were reduced in the cortex and unchanged in the hippocampus and striatum compared with controls. Maximal (-)-[3H]nicotine binding was reduced in both the cortex and hippocampus and unaltered in both the caudate nucleus and putamen. Alterations of the equilibrium dissociation constant were not observed for any ligand in any of the brain areas examined. The present results suggest that both the innominatocortical and the septohippocampal cholinergic systems degenerate in Parkinson's disease.(ABSTRACT TRUNCATED AT 250 WORDS)
Parameterization of temperature and spectral distortions in future CMB experiments
Creators: name: Pitrou, Cyril
name: Stebbins, Albert
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: CMB spectral distortions are induced by Compton collisions with electrons. We review the various schemes to characterize the anisotropic CMB with a non-Planckian spectrum. We advocate using logarithmically averaged temperature moments as the preferred language to describe these spectral distortions, both for theoretical modeling and observations. Numerical modeling is simpler, the moments are frame-independent, and in terms of scattering the mode truncation is exact.
description: 5 pages; discussion on chemical potential added
Brief Joanni Kirchero
Creators: name: Stand Solothurn
name: Staal, Hans Jakob von
Publisher: name: [s.n.]
Year: 1592

description: von Co[n]s[ule]s ac Senatus Civitatis Salodorensi apud Helvetios und [Hans Jakob vom Staal]
description: Brief Nr. 224.
description: Lateinisch
description: Verzeichnung=Description=Inventaire Juni 2016/August 2022 HAN-Katalogisierungsregeln iho/HBr
Two parallel insurance lines with simultaneous arrivals and risks correlated with inter-arrival times
Creators: name: Badila, E. S.
name: Boxma, O. J.
name: Resing, J. A. C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: 91B30, 60K25

description: We investigate an insurance risk model that consists of two reserves which receive income at fixed rates. Claims are being requested at random epochs from each reserve and the interclaim times are generally distributed. The two reserves are coupled in the sense that at a claim arrival epoch, claims are being requested from both reserves and the amounts requested are correlated. In addition, the claim amounts are correlated with the time elapsed since the previous claim arrival. We focus on the probability that this bivariate reserve process survives indefinitely. The infinite- horizon survival problem is shown to be related to the problem of determining the equilibrium distribution of a random walk with vector-valued increments with reflecting boundary. This reflected random walk is actually the waiting time process in a queueing system dual to the bivariate ruin process. Under assumptions on the arrival process and the claim amounts, and using Wiener-Hopf factor- ization with one parameter, we explicitly determine the Laplace-Stieltjes transform of the survival function, c.q., the two-dimensional equilibrium waiting time distribution. Finally, the bivariate transforms are evaluated for some examples, including for proportional reinsurance, and the bivariate ruin functions are numerically calculated using an efficient inversion scheme.
description: 24 pages, 6 figures
Proceedings in Marine Biology
Creators: name: Brüning, Anika
name: Däblitz, Almut
name: Hawliczek, Alessa
name: Kaijklina, Katja
name: Köppen, Nico
name: Liebertz, Frauke
name: Pechstein, Anne
name: Sachsenröder, Jana
name: Schultner, Eva
name: Schünemann, Jan
name: Seiffert, Franz
name: Stahl, Tina
name: Weiß, Benjamin
name: Zimmermann, Jonas
Publisher: name: Humboldt-Universität zu Berlin
Year: 2021
Subjects: subject: 570 Biologie

description: “Proceedings in Marine Biology” is an international journal publishing original research by graduate students on all aspects of marine biology. Subjects covered include: ecological surveys and population studies of oceanic, coastal and shore communities; physiology and experimental biology; taxonomy, morphology and life history of marine animals and plants. Papers are also published on techniques em- ployed at sea for sampling, recording, capture and observation of marine organisms.
description: Zeitschrift zur Kursabschlussreise der Humboldt-Universität zu Berlin (Deutschland) im Bereich Elektronenmikroskopie.