Thyroid Cancer: Pattern Of Recurrence And Complications Of Redo Surgery
Creators: name: Abdelkhalek, Mohamed
Publisher: name: figshare
Year: 2023
Subjects: Surgery

description: Methods This is a retrospective study, where the institutional registry at the Oncology Center, Mansoura University (OCMU) was thor- oughly revised for recurrent thyroid cancer cases that attended the hospital from January 2006 till November 2019. 112 pa- tients were recruited. Patients with pathologically proven re- current thyroid cancer were included, while patients with in- adequate data registry or with thyroid lymphoma were ex- cluded. 89 patients fulfilled the inclusion criteria and were in- cluded in the study. The primary endpoint was disease persis- tence defined as presence of any structural evidence of the dis- ease (locoregional or distant) at the end of follow up period whether this represent residual after surgery and adjuvant therapy or another recurrent event. While the secondary end- points were the site/distribution of recurrence and complica- tions of redo-surgery. The hospital registry including the pa- tients follow up visits were traced till February 2020. The data of these patients were analyzed using SPSS ver- sion 22 (Inc, Chicago, IL). Continuous variables are presented as mean when symmetrical or median and range when asym- metrical. Categorical variables are presented as proportions. Comparisons were done using Chi-square test for nominal var- iables and Fischer exact test for those with value less than 5 squares. In addition, Mann-Whitney and student-t-tests were used for continuous variables according to their pattern of dis- tribution. Disease free survival after primary surgery was cal- culated by Kaplan-Meier curve with significance measured ac- cording to log rank test. Multivariate analysis was done using logistic regression model. P value &lt;0.05 was considered signif- icant.Methods <br> This is a retrospective study, where the institutional registry at <br> the Oncology Center, Mansoura University (OCMU) was thor- <br> oughly revised for recurrent thyroid cancer cases that attended <br> the hospital from January 2006 till November 2019. 112 pa- <br> tients were recruited. Patients with pathologically proven re- <br> current thyroid cancer were included, while patients with in- <br> adequate data registry or with thyroid lymphoma were ex- <br> cluded. 89 patients fulfilled the inclusion criteria and were in- <br> cluded in the study. The primary endpoint was disease persis- <br> tence defined as presence of any structural evidence of the dis- <br> ease (locoregional or distant) at the end of follow up period <br> whether this represent residual after surgery and adjuvant <br> therapy or another recurrent event. While the secondary end- <br> points were the site/distribution of recurrence and complica- <br> tions of redo-surgery. The hospital registry including the pa- <br> tients follow up visits were traced till February 2020. <br> The data of these patients were analyzed using SPSS ver- <br> sion 22 (Inc, Chicago, IL). Continuous variables are presented <br> as mean when symmetrical or median and range when asym- <br> metrical. Categorical variables are presented as proportions. <br> Comparisons were done using Chi-square test for nominal var- <br> iables and Fischer exact test for those with value less than 5 <br> squares. In addition, Mann-Whitney and student-t-tests were <br> used for continuous variables according to their pattern of dis- <br> tribution. Disease free survival after primary surgery was cal- <br> culated by Kaplan-Meier curve with significance measured ac- <br> cording to log rank test. Multivariate analysis was done using <br> logistic regression model. P value &lt;0.05 was considered signif- <br> icant.Thyroid Cancer: Pattern Of Recurrence And Complications Of Redo Surg