cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Supplementary document for Distinguish optical and acoustic phonon temperatures of supported 2D materials by nanosecond time-resolved Raman scattering - 7154262.pdf
Creators: name: Rahbar, Mahya
name: Al Keyyam, Ibrahim
name: Liu, Jing
name: Wang, Xinwei
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Additional experimental and analysis details
Supplementary document for Distinguish optical and acoustic phonon temperatures of supported 2D materials by nanosecond time-resolved Raman scattering - 7154262.pdf
Creators: name: Rahbar, Mahya
name: Al Keyyam, Ibrahim
name: Liu, Jing
name: Wang, Xinwei
Publisher: name: Optica Publishing Group
Year: 2024
Subjects: Uncategorized

description: Additional experimental and analysis details
Evaluation of PET/MRI for Tumor Volume Delineation for Head and Neck Cancer
Creators: name: Mullins, Brandon T.
name: Falchook, Aaron D.
name: Chera, Bhishamjit S.
name: Sills, Tiffany M.
name: Shen, Dinggang
name: Dance, Michael
name: Das, Shiva K.
name: Wang, Kyle
name: Lian, Jun
name: He, Kelei
name: Huang, Benjamin Y.
name: Lin, Weili
Publisher: name: Frontiers
Year: 2017

description: INTRODUCTION: Computed tomography (CT), combined positron emitted tomography and CT (PET/CT), and magnetic resonance imaging (MRI) are commonly used in head and neck radiation planning. Hybrid PET/MRI has garnered attention for potential added value in cancer staging and treatment planning. Herein, we compare PET/MRI vs. planning CT for head and neck cancer gross tumor volume (GTV) delineation. MATERIAL AND METHODS: We prospectively enrolled patients with head and neck cancer treated with definitive chemoradiation to 60-70Gy using IMRT. We performed pretreatment contrast-enhanced planning CT and gadolinium-enhanced PET/MRI. Primary and nodal volumes were delineated on planning CT (GTV-CT) prospectively before treatment and PET/MRI (GTV-PET/MRI) retrospectively after treatment. GTV-PET/MRI was compared to GTV-CT using separate rigid registrations for each tumor volume. The Dice similarity coefficient (DSC) metric evaluating spatial overlap and modified Hausdorff distance (mHD) evaluating mean orthogonal distance difference were calculated. Minimum dose to 95% of GTVs (D95) was compared. RESULTS: Eleven patients were evaluable (10 oropharynx, 1 larynx). Nine patients had evaluable primary tumor GTVs and seven patients had evaluable nodal GTVs. Mean primary GTV-CT and GTV-PET/MRI size were 13.2 and 14.3cc, with mean intersection 8.7cc, DSC 0.63, and mHD 1.6mm. D95 was 65.3Gy for primary GTV-CT vs. 65.2Gy for primary GTV-PET/MRI. Mean nodal GTV-CT and GTV-PET/MRI size were 19.0 and 23.0cc, with mean intersection 14.4cc, DSC 0.69, and mHD 2.3mm. D95 was 62.3Gy for both nodal GTV-CT and GTV-PET/MRI. CONCLUSION: In this series of patients with head and neck (primarily oropharynx) cancer, PET/MRI and CT-GTVs had similar volumes (though there were individual cases with larger differences) with overall small discrepancies in spatial overlap, small mean orthogonal distance differences, and similar radiation doses.
Representing the economic boom and its anxieties: Italy and Japan
Creators: name: Kaneda, Hiromi
Publisher: name: No Publisher Supplied
Year: 2025

description: In my dissertation, I explore the cultural anxieties surrounding the economic miracles of Japan (1950-1970) and Italy (1958-1963) in the post-war period, focusing on the interplay of American influence, tradition, and modernity, as well as the evolving constructions of masculinity, gender roles, and patriarchal structures. This study highlights the shared struggles and distinct responses to rapid modernization and societal transformation by examining key literary and cinematic works from both nations. I argue that the economic miracles in Japan and Italy reveal common struggles with identity, gender, and societal expectations during rapid change. By comparing the two nations, this work demonstrates how similar challenges can manifest differently in unique cultural contexts while highlighting shared anxieties. First, I establish a connection between Italy and Japan by analyzing the translations of tankas by Gherardo Marone and Shimoi Harukichi. Then, I examine texts and cinematic representations of Italy and Japan: Un amore (1963) by Dino Buzzati, Una bambolona (1967) by Alba De Cespedes, American Hijiki (1967) by Nosaka Akiyuki, and the films Un amore (1965) by Gianni Vernuccio, La bambolona (1968) by Franco Giraldi, The Life of Oharu (1952) by Kenji Mizoguchi, and Flowing (1956) by Naruse Mikio. I explore the patriarchal anxiety in a changing world – Eastern and Western – and how the rapid economic growth intensified these anxieties about masculinity and gender roles. I also show how modernization and consumer culture commodified the relationships between gender roles: women were reduced to objects of desire, and they fought against the patriarchal system to revert it. In Chapter One, I establish a historical frame for Italy and Japan, exploring the dichotomy of tradition vs. modernity and the theme of alienation. In Chapter Two, I analyze the tankas translated in La Diana by Gherardo Marone and Harukichi Shimoi. In Chapter Three, I examine the commodification of gender roles, the alienation caused by consumer culture and patriarchal society, and the threat to masculinity in Italian novels and films. Finally, Chapter Four investigates films depicting women’s lives constrained by patriarchal structures amidst Japan’s modernization.
Supplementary document for SSCDN: A Spatial-Spectral Collaborative Network for Hyperspectral Image Denoising - 7154327.pdf
Creators: name: Li, kaixiang
name: Li, Renjian
name: Li, Guiye
name: Liu, Shaojun
name: He, Zhengdi
name: Zhang, Meng
name: chen, lingling
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: supplementary information
Evidence for human milk as a biological system and recommendations for study design-a report from "Breastmilk Ecology: Genesis of Infant Nutrition (BEGIN)" Working Group 4
Creators: name: Donovan, Sharon M.
name: Steiber, Alison L.
name: Raiten, Daniel J.
name: Becker, Martin
name: Aghaeepour, Nima
name: Andres, Aline
name: Slupsky, Carolyn M.
name: Carlson, Susan E.
name: Jaervinen, Kirsi M.
name: Lin, Weili
name: Azad, Meghan B.
name: Lönnerdal, Bo
Publisher: name: Elsevier
Year: 2023

description: Human milk contains all of the essential nutrients required by the infant within a complex matrix that enhances the bioavailability of many of those nutrients. In addition, human milk is a source of bioactive components, living cells and microbes that facilitate the transition to life outside the womb. Our ability to fully appreciate the importance of this matrix relies on the recognition of short- and long-term health benefits and, as highlighted in previous sections of this supplement, its ecology (i.e., interactions among the lactating parent and breastfed infant as well as within the context of the human milk matrix itself). Designing and interpreting studies to address this complexity depends on the availability of new tools and technologies that account for such complexity. Past efforts have often compared human milk to infant formula, which has provided some insight into the bioactivity of human milk, as a whole, or of individual milk components supplemented with formula. However, this experimental approach cannot capture the contributions of the individual components to the human milk ecology, the interaction between these components within the human milk matrix, or the significance of the matrix itself to enhance human milk bioactivity on outcomes of interest. This paper presents approaches to explore human milk as a biological system and the functional implications of that system and its components. Specifically, we discuss study design and data collection considerations and how emerging analytical technologies, bioinformatics, and systems biology approaches could be applied to advance our understanding of this critical aspect of human biology.
Supplementary document for Unidirectional and highly dispersive grating emitters for silicon photonic beam steerers - 7155476.pdf
Creators: name: Chen, Fa-Lun
name: Yiu, Gow-Zin
name: Chang, You-Chia
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
QCH897356 Supplemental Material - Supplemental material for Factors Associated With Colonoscopy Compliance Based on Health Belief Model in a Community-Based Colorectal Cancer Screening Program Shanghai, China
Creators: name: He, Lihua
name: Gao, Shuna
name: Tao, Sha
name: Li, Weiyi
name: Du, Juan
name: Ji, Yunfang
name: Wang, Yejing
Publisher: name: SAGE Journals
Year: 2019
Subjects: Public Health and Health Services not elsewhere classified

description: Supplemental material, QCH897356 Supplemental Material for Factors Associated With Colonoscopy Compliance Based on Health Belief Model in a Community-Based Colorectal Cancer Screening Program Shanghai, China by Lihua He, Shuna Gao, Sha Tao, Weiyi Li, Juan Du, Yunfang Ji and Yejing Wang in International Quarterly of Community Health Education
Additional file 5 of Effects of opium use on one-year major adverse cardiovascular events (MACE) in the patients with ST-segment elevation MI undergoing primary PCI: a propensity score matched - machine learning based study
Creators: name: Jenab, Yaser
name: Hedayat, Behnam
name: Karimi, Amirali
name: Taaghi, Sarah
name: Ghorashi, Seyyed Mojtaba
name: Ekhtiari, Hamed
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 5: Supplementary Figure 2. Correlation matrix of the independent numerical variables.
AS1411aptamer conjugated liposomes for targeted delivery of arsenic trioxide in mouse xenograft model of melanoma cancer
Creators: name: Razavi, Fatemeh Shariat
name: Kouchak, Maryam
name: Karampour, Neda Sistani
name: Mahdavinia, Masoud
name: Khorasgani, Zahra Nazari
name: Rezaie, Annahita
name: Rahbar, Nadereh
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer

description: Development of AS1411aptamer-conjugated liposomes for targeted delivery of arsenic trioxide is the primary goal of this study. AS1411aptamer was used as ligand to target nucleolin, which is highly expressed on the surface of melanoma cancer cells. The targeted liposomes were constructed by the thin film method, and arsenic trioxide was loaded as cobalt (II) hydrogen arsenite (CHA) to increase the loading efficiency and stability of the liposomes. The liposomal structure was characterized by Fourier Transform Infrared Spectroscopy (FT-IR) and field emission scanning electron microscopy (FESEM). In addition, particle sizes and zeta potential of the CHA-loaded liposomes (CHAL) and aptamer-functionalized CHA-loaded liposomes (AP-CHAL) were determined. In vitro cytotoxicity of CHAL and AP-CHAL were evaluated using MTT assay in murine melanoma (B16) and mouse embryonic fibroblast (MEF) cell lines. The encapsulation efficiency of CHAL and AP-CHAL was reported as 60.2 ± 6.5% and 58.7 ± 4.2%, respectively. In vivo antitumor activity of CHAL and AP-CHAL in the B16 tumor-xenograft mouse model was dramatically observed. All mice of both groups survived until the end of treatment and showed body weight gain. The tumor protrusion completely disappeared in 50% of the mice in these groups. Furthermore, histopathology studies demonstrated that CHAL and AP-CHAL did not induce significant toxicity in healthy mice tissues. However, unlike the CHAL group, which showed an initial increase in tumor volume, a specific antitumor effect was observed in the AP-CHAL group from the beginning of treatment. The results showed that AP-CHAL can be used as an effective drug delivery system with high potential in the treatment of solid tumors.
CRE896404_Supplemental_Appendices – Supplemental material for Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review
Creators: name: Oates, Lloyd L
name: Moghaddam, Nima
name: Evangelou, Nikos
name: Nair, Roshan Das
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: FOS: Health sciences

description: Supplemental material, CRE896404_Supplemental_Appendices for Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review by Lloyd L Oates, Nima Moghaddam, Nikos Evangelou and Roshan das Nair in Clinical Rehabilitation
Scaling-up of climate resilient housing in Gorakhpur, India
Creators: name: IIED, London
Publisher: name: Zenodo
Year: 2016

description: The poor in cities are faced with dual challenge – that of housing shortages and ofincreased vulnerability to climate change impacts, given the location of their houses aswell as their capacities to recover. More often than not, housing for the urban poor is notonly an asset, but also a place for income generation. Based on consultations with keystakeholder groups in Gorakhpur city in eastern India, this paper examines the housingvulnerability challenges faced by the urban poor. The paper analyses the existingconstraints within the current financial mechanisms for home mortgages, especially forlow income group households; the lack of technical capacities of the local masons onlow cost and climate resilient building techniques; and the absence of information at thehousehold level towards creating a demand for climate resilient housing construction.Recognising and revamping the micro-finance mechanisms to cater to the housingneeds of this section of the population (labourers, daily wagers, petty shop owners,etc.) who do not have the necessary documentation, such as proof of income and landtitles, are some of the suggestions put forward to improve the cost and accessibility offinancing. Building the capacity of local masons on climate resilient building techniques– as part of the government’s skills development programme – is also an importantpart of resilience building at the local level for the urban poor. To create a demand forclimate resilient housing, there is a need for awareness generation amongst the people,coupled with policies that mandate the linking of home loans with resilient designs andtechniques.
Supplementary document for Micro magnetic field sensor based on bifunctional diodes - 7155883.pdf
Creators: name: Wu, Wenxuan
name: Ye, Ziqi
name: Yan, Jiabin
name: Fu, Kang
name: Fu, Jianwei
name: Liu, Pengzhan
name: Su, Yuxuan
name: Wang, Yongjin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Photonics, Optoelectronics and Optical Communications

description: This supplementary document contains a description of the process to fabricate the multiple-quantum well (MQW) optoelectronic integrated chip and an introduction to magnetic fluids (MFs).
Evolutionary rescue via transgenerational plasticity: Evidence and implications for conservation
Creators: name: Harmon, Emily A.
name: Pfennig, David W.
Publisher: name: Wiley
Year: 2021

description: When a population experiences severe stress from a changing environment, evolution by natural selection can prevent its extinction, a process dubbed "evolutionary rescue." However, evolution may be unable to track the sort of rapid environmental change being experienced by many modern-day populations. A potential solution is for organisms to respond to environmental change through phenotypic plasticity, which can buffer populations against change and thereby buy time for evolutionary rescue. In this review, we examine whether this process extends to situations in which the environmentally induced response is passed to offspring. As we describe, theoretical and empirical studies suggest that such "transgenerational plasticity" can increase population persistence. We discuss the implications of this process for conservation biology, outline potential limitations, and describe some applications. Generally, transgenerational plasticity may be effective at buying time for evolutionary rescue to occur.
Supplemental Material
Creators: name: Schnabl-Feichter, Eva
name: Schnabl, Sophia
name: Tichy, Alexander
name: Gumpenberger, Michaela
name: Bockstahler, Barbara
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Lameness grades
Ad-hoc devised phototraps unravel Cerambyx miles diel activity in the wild (Coleoptera: Cerambycidae)
Creators: name: Torres-Vila, Luis M.
name: Mendiola-Díaz, Francisco Javier
name: López-Calvo, Rafael
name: Ponce-Escudero, Francisco
name: Sánchez-González, Álvaro
name: Fernández-Moreno, Félix
Publisher: name: Fragmenta entomologica
Year: 2023

description: Longhorn beetles are often categorized as diurnal, crepuscular or nocturnal depending on the diel (day-night) time window at which adults are active. A precise knowledge of the diel activity pattern in these species is essential to understand the selective forces involved in, and the adaptations resulting from, the evolution of circadian rhythms. The genus Cerambyx includes both diurnal and crepuscular/nocturnal species. In the case of Cerambyx miles Bonelli, 1812, a usually scarce and localised species, diel activity remains poorly understood. While for some authors this longhorn is diurnal, for others it is crepuscular/nocturnal. In order to resolve this historical discrepancy, we studied the diel activity of C. miles in the wild in 2020 and 2021 using ad hoc devised phototraps (with and without capture) and we examine to what extent our field results conformed to literature. Our data (n = 139 captures/sightings) show that about 94% of the activity of C. miles is diurnal, 5% crepuscular, and less than 1% nocturnal. Diel activity started at dawn, raised progressively during the morning, peaked in the late afternoon (17.00-20.00 h) and declined abruptly just before dusk. Our field results were not consistent with literature data (n = 103 diel activity records retrieved from 79 references), in which diel activity was scored as 60% diurnal, 26% crepuscular and 14% nocturnal. We argue possible causes involved in the literature bias and we discuss the diel activity of C. miles from a behavioural, ecological and evolutionary perspective.
description: Fragmenta entomologica, Vol. 55 No. 1 (2023)
Supplemental Material, Online_Appendices_a_e - “Affective News” and Attitudes: A Multi-Topic Experiment of Attitude Impacts From Political News and Fiction
Creators: name: Knobloch-Westerwick, Silvia
name: Robinson, Melissa
name: Frazer, Rebecca
name: Schutz, Emily
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Education

description: Supplemental Material, Online_Appendices_a_e for “Affective News” and Attitudes: A Multi-Topic Experiment of Attitude Impacts From Political News and Fiction by Silvia Knobloch-Westerwick, Melissa Robinson, Rebecca Frazer and Emily Schutz in Journalism & Mass Communication Quarterly
Examining a new prosocial risk-taking scale in a longitudinal sample of ethnically diverse adolescents
Creators: name: Moreira, Joio F. Guassi
name: Prinstein, Mitchell J.
name: Armstrong-Carter, Emma
name: Telzer, Eva H.
name: T., Kathy
Publisher: name: Wiley
Year: 2021

description: INTRODUCTION: This longitudinal study designed and tested the validity of a new measure of prosocial risk taking - risks that individuals take in order to help others. METHODS: The sample was racially and ethnically diverse adolescents in the rural Southeastern United States (N = 867; Mage = 12.82 years, 10-14 years at Wave 1; 50% Girls, 33% White non-Latinx, 27% Latinx, 20% Black, 20% Mixed/Other race/ethnicity). Adolescents completed self-report measures of the new prosocial risk-taking scale at baseline and one- and two-year follow-ups. RESULTS: Confirmatory factor analysis demonstrated excellent model fit with a 6-item single factor score. Further, the scale demonstrated good test-retest reliability at one and two-year follow ups. The scale also demonstrated convergent validity, such that prosocial risk taking was positively correlated with prosocial tendencies, empathy, and sensation seeking, and negatively correlated with negative risk-taking behavior and risk tolerance. Finally, we found significant differences by race/ethnicity (but not by gender) in prosocial risk taking, which were not attributable to measurement invariance, and should be interpreted in the context of ongoing societal inequalities between youth. CONCLUSIONS: The new Prosocial Risk-Taking Scale yielded reliable scores in our sample. It may be used in future research to investigate individual differences in adolescents' prosocial risk taking, developmental change in prosocial risk taking, and the significance of prosocial risk taking for adolescents' emotional and social adaptation.
Supplementary document for High-dimensional quantum key distribution using orbital angular momentum of single photons from a colloidal quantum dot at room temperature - 7156059.pdf
Creators: name: Halevi, Dotan
name: Lubotzky, Boaz
name: Sulimany, Kfir
name: Bowes, Eric
name: Hollingsworth, Jennifer
name: Bromberg, Yaron
name: Rapaport, Ronen
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supp doc
Additional file 1 of 99mTc-MAA accumulation within tumor in preoperative lung perfusion SPECT/CT associated with occult lymph node metastasis in patients with clinically N0 non-small cell lung cancer
Creators: name: Murad, Vanessa
name: Suh, Minseok
name: Choi, Hongyoon
name: Cheon, Gi Jeong
name: Na, Kwon Joong
name: Kim, Young Tae
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Cell Biology
Molecular Biology
Cancer

description: Supplementary Material 1
Supplemental Material, Supplement_Table_1 - Improvement of Neurological Function in Rats with Ischemic Stroke by Adipose-derived Pericytes
Creators: name: Ogay, Vyacheslav
name: Kumasheva, Venera
name: Li, Yelena
name: Mukhlis, Sholpan
name: Sekenova, Aliya
name: Farkhad Olzhayev
name: Tsoy, Andrey
name: Umbayev, Baurzhan
name: Askarova, Sholpan
name: Shpekov, Azat
name: Kaliyev, Assylbek
name: Zhetpisbayev, Berik
name: Makhambetov, Yerbol
name: Akshulakov, Serik
name: Saparov, Arman
name: Ramankulov, Yerlan
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine
Cell Biology

description: Supplemental Material, Supplement_Table_1 for Improvement of Neurological Function in Rats with Ischemic Stroke by Adipose-derived Pericytes by Vyacheslav Ogay, Venera Kumasheva, Yelena Li, Sholpan Mukhlis, Aliya Sekenova, Farkhad Olzhayev, Andrey Tsoy, Baurzhan Umbayev, Sholpan Askarova, Azat Shpekov, Assylbek Kaliyev, Berik Zhetpisbayev, Yerbol Makhambetov, Serik Akshulakov, Arman Saparov and Yerlan Ramankulov in Cell Transplantation
Supplementary document for GUNet++: Guided U-Net based Compact Image Representation with Improved Reconstruction Mechanism - 7157196.pdf
Creators: name: Banerjee, Nirwan
name: Malakar, Samir
name: Horsch, Alexander
name: Prasad, Dilip
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplementary document
Examining cognitive control and reward interactions in adolescent externalizing symptoms
Creators: name: Davidow, Juliet Y.
name: Van Dijk, Koene R.A.
name: Sheridan, Margaret A.
name: Hollinshead, Marisa O.
name: Rosen, Bruce R.
name: Rodriguez-Thompson, Anais M.
name: Santillana, Rosario M.
name: Somerville, Leah H.
name: Meyer, Kristin M.
name: Snyder, Jenna
name: Bustamante, Constanza M. Vidal
Publisher: name: Elsevier
Year: 2020

description: During adolescence, rapid development and reorganization of the dopaminergic system supports increasingly sophisticated reward learning and the ability to exert behavioral control. Disruptions in the ability to exert control over previously rewarded behavior may underlie some forms of adolescent psychopathology. Specifically, symptoms of externalizing psychopathology may be associated with difficulties in flexibly adapting behavior in the context of reward. However, the direct interaction of cognitive control and reward learning in adolescent psychopathology symptoms has not yet been investigated. The present study used a Research Domain Criteria framework to investigate whether behavioral and neuronal indices of inhibition to previously rewarded stimuli underlie individual differences in externalizing symptoms in N = 61 typically developing adolescents. Using a task that integrates the Monetary Incentive Delay and Go-No-Go paradigms, we observed a positive association between externalizing symptoms and activation of the left middle frontal gyrus during response inhibition to cues with a history of reward. These associations were robust to controls for internalizing symptoms and neural recruitment during inhibition of cues with no reward history. Our findings suggest that inhibitory control over stimuli with a history of reward may be a useful marker for future inquiry into the development of externalizing psychopathology in adolescence.
Examining the mechanistic relationship of APC/CCDH1 and its interphase inhibitor EMI1
Creators: name: Bolhuis, Derek L.
name: Welsh, Kaeli A.
name: Martinez-Chacin, Raquel C.
name: Brown, Nicholas G.
name: Bodrug, Tatyana
name: Cui, Liying
name: Emanuele, Michael J.
Publisher: name: Wiley
Year: 2022

description: Proper protein destruction by the ubiquitin (Ub)-proteasome system is vital for a faithful cell cycle. Hence, the activity of Ub ligases is tightly controlled. The Anaphase-Promoting Complex/Cyclosome (APC/C) is a 1.2MDa Ub ligase responsible for mitotic progression and G1 maintenance. At the G1/S transition, the APC/C is inhibited by EMI1 to prevent APC/C-dependent polyubiquitination of cell cycle effectors. EMI1 uses several interaction motifs to block the recruitment of APC/C substrates as well as the APC/C-associated E2s, UBE2C, and UBE2S. Paradoxically, EMI1 is also an APC/C substrate during G1. Using a comprehensive set of enzyme assays, we determined the context-dependent involvement of the EMI1 motifs in APC/C-dependent ubiquitination of EMI1 and other substrates. Furthermore, we demonstrated that an isolated C-terminal peptide fragment of EMI1 activates APC/C-dependent substrate priming by UBE2C. Together, these findings reveal the multiple roles of the EMI1 C-terminus for G1 maintenance and the G1/S transition.
Excited-state proton-coupled electron transfer within ion pairs
Creators: name: Swords, Wesley B.
name: Hammarström, Leif
name: Meyer, Gerald J.
Publisher: name: Royal Society of Chemistry (RSC)
Year: 2020

description: The use of light to drive proton-coupled electron transfer (PCET) reactions has received growing interest, with recent focus on the direct use of excited states in PCET reactions (ES-PCET). Electrostatic ion pairs provide a scaffold to reduce reaction orders and have facilitated many discoveries in electron-transfer chemistry. Their use, however, has not translated to PCET. Herein, we show that ion pairs, formed solely through electrostatic interactions, provide a general, facile means to study an ES-PCET mechanism. These ion pairs formed readily between salicylate anions and tetracationic ruthenium complexes in acetonitrile solution. Upon light excitation, quenching of the ruthenium excited state occurred through ES-PCET oxidation of salicylate within the ion pair. Transient absorption spectroscopy identified the reduced ruthenium complex and oxidized salicylate radical as the primary photoproducts of this reaction. The reduced reaction order due to ion pairing allowed the first-order PCET rate constants to be directly measured through nanosecond photoluminescence spectroscopy. These PCET rate constants saturated at larger driving forces consistent with approaching the Marcus barrierless region. Surprisingly, a proton-transfer tautomer of salicylate, with the proton localized on the carboxylate functional group, was present in acetonitrile. A pre-equilibrium model based on this tautomerization provided non-adiabatic electron-transfer rate constants that were well described by Marcus theory. Electrostatic ion pairs were critical to our ability to investigate this PCET mechanism without the need to covalently link the donor and acceptor or introduce specific hydrogen bonding sites that could compete in alternate PCET pathways.
Existence of Functional Connectome Fingerprint during Infancy and Its Stability over Months.
Creators: name: Hu, Dan
name: Li, Guoshi
name: Wang, Li
name: Wu, Zhengwang
name: Zhou, Zhen
name: Wang, Fan
name: Zhang, Han
name: Lin, Weili
name: Li, Gang
Publisher: name: Society for Neuroscience
Year: 2021

description: The functional connectome fingerprint is a cluster of individualized brain functional connectivity patterns that are capable of distinguishing one individual from others. Although its existence has been demonstrated in adolescents and adults, whether such individualized patterns exist during infancy is barely investigated despite its importance in identifying the origin of the intrinsic connectome patterns that potentially mirror distinct behavioral phenotypes. To fill this knowledge gap, capitalizing on a longitudinal high-resolution structural and resting-state functional MRI dataset with 104 human infants (53 females) with 806 longitudinal scans (age, 16-876 d) and infant-specific functional parcellation maps, we observe that the brain functional connectome fingerprint may exist since infancy and keeps stable over months during early brain development. Specifically, we achieve an ~78% individual identification rate by using ~5% selected functional connections, compared with the best identification rate of 60% without connection selection. The frontoparietal networks recognized as the most contributive networks in adult functional connectome fingerprinting retain their superiority in infants despite being widely acknowledged as rapidly developing systems during childhood. The existence and stability of the functional connectome fingerprint are further validated on adjacent age groups. Moreover, we show that the infant frontoparietal networks can reach similar accuracy in predicting individual early learning composite scores as the whole-brain connectome, again resembling the observations in adults and highlighting the relevance of functional connectome fingerprint to cognitive performance. For the first time, these results suggest that each individual may retain a unique and stable marker of functional connectome during early brain development. SIGNIFICANCE STATEMENT Functional connectome fingerprinting during infancy featuring rapid brain development remains almost uninvestigated even though it is essential for understanding the early individual-level intrinsic pattern of functional organization and its relationship with distinct behavioral phenotypes. With an infant-tailored functional connection selection and validation strategy, we strive to provide the delineation of the infant functional connectome fingerprint by examining its existence, stability, and relationship with early cognitive performance. We observe that the brain functional connectome fingerprint may exist since early infancy and remains stable over months during the first 2 years. The identified key contributive functional connections and networks for fingerprinting are also verified to be highly predictive for cognitive score prediction, which reveals the association between infant connectome fingerprint and cognitive performance.
Exogenous vs. endogenous attention: Shifting the balance of fronto-parietal activity
Creators: name: Du, Feng
name: Meyer, Kristin N.
name: Parks, Emily
name: Hopfinger, Joseph B.
Publisher: name: Elsevier
Year: 2018

description: Despite behavioral and electrophysiological evidence for dissociations between endogenous (voluntary) and exogenous (reflexive) attention, fMRI results have yet to consistently and clearly differentiate neural activation patterns between these two types of attention. This study specifically aimed to determine whether activity in the dorsal fronto-parietal network differed between endogenous and exogenous conditions. Participants performed a visual discrimination task in endogenous and exogenous attention conditions while undergoing fMRI scanning. Analyses revealed robust and bilateral activation throughout the dorsal fronto-parietal network for each condition, in line with many previous results. In order to investigate possible differences in the balance of neural activity within this network with greater sensitivity, a priori regions of interest (ROIs) were selected for analysis, centered on the frontal eye fields (FEF) and intraparietal sulcus (IPS) regions identified in previous studies. The results revealed a significant interaction between region, condition, and hemisphere. Specifically, in the left hemisphere, frontal areas were more active than parietal areas, but only during endogenous attention. Activity in the right hemisphere, in contrast, remained relatively consistent for these regions across conditions. Analysis of this activity over time indicates that this left-hemispheric regional imbalance is present within the FEF early, at 3-6.5 seconds post-stimulus presentation, whereas a regional imbalance in the exogenous condition is not evident until 6.5-8 seconds post-stimulus presentation. Overall, our results provide new evidence that although the dorsal fronto-parietal network is indeed associated with both types of attentional orienting, regions of the network are differentially engaged over time and across hemispheres depending on the type of attention.
Supplementary document for Enhancing MINFLUX 3D imaging precision by vortex interference - 7157495.pdf
Creators: name: wang, wei
name: huang, zengxin
name: Li, hangfeng
name: Kanchanawong, Pakorn
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Classical and Physical Optics

description: supplementary document 1
Exon level machine learning analyses elucidate novel candidate miRNA targets in an avian model of fetal alcohol spectrum disorder
Creators: name: Garic, Ana
name: Al-Shaer, Abrar E.
name: Smith, Susan M.
name: Flentke, George R.
name: Berres, Mark E.
Publisher: name: Public Library of Science (PLoS)
Year: 2019

description: Gestational alcohol exposure causes fetal alcohol spectrum disorder (FASD) and is a prominent cause of neurodevelopmental disability. Whole transcriptome sequencing (RNA-Seq) offer insights into mechanisms underlying FASD, but gene-level analysis provides limited information regarding complex transcriptional processes such as alternative splicing and non-coding RNAs. Moreover, traditional analytical approaches that use multiple hypothesis testing with a false discovery rate adjustment prioritize genes based on an adjusted p-value, which is not always biologically relevant. We address these limitations with a novel approach and implemented an unsupervised machine learning model, which we applied to an exon-level analysis to reduce data complexity to the most likely functionally relevant exons, without loss of novel information. This was performed on an RNA-Seq paired-end dataset derived from alcohol-exposed neural fold-stage chick crania, wherein alcohol causes facial deficits recapitulating those of FASD. A principal component analysis along with k-means clustering was utilized to extract exons that deviated from baseline expression. This identified 6857 differentially expressed exons representing 1251 geneIDs; 391 of these genes were identified in a prior gene-level analysis of this dataset. It also identified exons encoding 23 microRNAs (miRNAs) having significantly differential expression profiles in response to alcohol. We developed an RDAVID pipeline to identify KEGG pathways represented by these exons, and separately identified predicted KEGG pathways targeted by these miRNAs. Several of these (ribosome biogenesis, oxidative phosphorylation) were identified in our prior gene-level analysis. Other pathways are crucial to facial morphogenesis and represent both novel (focal adhesion, FoxO signaling, insulin signaling) and known (Wnt signaling) alcohol targets. Importantly, there was substantial overlap between the exomes themselves and the predicted miRNA targets, suggesting these miRNAs contribute to the gene-level expression changes. Our novel application of unsupervised machine learning in conjunction with statistical analyses facilitated the discovery of signaling pathways and miRNAs that inform mechanisms underlying FASD.
Additional file 1 of Environmental factors influencing detection efficiency of an acoustic telemetry array and consequences for data interpretation
Creators: name: Long, Michael
name: Jordaan, Adrian
name: Castro-Santos, Theodore
Publisher: name: figshare
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Pearson correlation coefficient matrix for all predictor variables and observed detection efficiency throughout all test sessions.
Supplementary document for Mechanoluminescence of ZnS: Cu@Al2O3 enabled optical fiber microlens passive tactile sensor for hardness recognition - 7157572.pdf
Creators: name: Dai, Penghui
name: cong, zhicheng
name: jiang, hong
name: Jiang, Chunlei
name: chen, pengyi
name: sun, yu
name: Dong, Taiji
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Fig.S1 and S2
Additional file 2 of Correction: First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors
Creators: name: Cole, Christopher B.
name: Morelli, Maria Pia
name: Fantini, Massimo
name: Miettinen, Markku
name: Fetsch, Patricia
name: Peer, Cody
name: Figg, William D.
name: Yin, Tyler
name: Houston, Nicole
name: McCoy, Ann
name: Lipkowitz, Stanley
name: Zimmer, Alexandra
name: Lee, Jung-min
name: Pavelova, Miroslava
name: Villanueva, Erin N.
name: Trewhitt, Kathryn
name: Solarz, B. Brooke
name: Fergusson, Maria
name: Mavroukakis, Sharon A.
name: Zaki, Anjum
name: Tsang, Kwong Y.
name: Arlen, Philip M.
name: Annunziata, Christina M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 8: NEO-201 protocol.
title: Gesundheitsförderung und Prävention in der Pflege
Creators: name: Schaeffer, Doris
name: Horn, Annett
Publisher: name: Bundeszentrale für gesundheitliche Aufklärung (BZgA)
Year: 2023

description: Leitbegriffe der Gesundheitsförderung und Prävention. Glossar zu Konzepten, Strategien und Methoden.
Exploring folding patterns of infant cerebral cortex based on multi-view curvature features: Methods and applications
Creators: name: Lin, Weili
name: Meng, Yu
name: Wang, Li
name: Xia, Shunren
name: Rekik, Islem
name: Wu, Zhengwang
name: Duan, Dingna
name: Shen, Dinggang
name: Gilmore, John H
name: Li, Gang
Publisher: name: Elsevier
Year: 2018

description: The highly convoluted cortical folding of the human brain is intriguingly complex and variable across individuals. Exploring the underlying representative patterns of cortical folding is of great importance for many neuroimaging studies. At term birth, all major cortical folds are established and are minimally affected by the complicated postnatal environments; hence, neonates are the ideal candidates for exploring early postnatal cortical folding patterns, which yet remain largely unexplored. In this paper, we propose a novel method for exploring the representative regional folding patterns of infant brains. Specifically, first, multi-view curvature features are constructed to comprehensively characterize the complex characteristics of cortical folding. Second, for each view of curvature features, a similarity matrix is computed to measure the similarity of cortical folding in a specific region between any pair of subjects. Next, a similarity network fusion method is adopted to nonlinearly and adaptively fuse all the similarity matrices into a single one for retaining both shared and complementary similarity information of the multiple characteristics of cortical folding. Finally, based on the fused similarity matrix and a hierarchical affinity propagation clustering approach, all subjects are automatically grouped into several clusters to obtain the representative folding patterns. To show the applications, we have applied the proposed method to a large-scale dataset with 595 normal neonates and discovered representative folding patterns in several cortical regions, i.e., the superior temporal gyrus (STG), inferior frontal gyrus (IFG), precuneus, and cingulate cortex. Meanwhile, we have revealed sex difference in STG, IFG, and cingulate cortex, as well as hemispheric asymmetries in STG and cingulate cortex in terms of cortical folding patterns. Moreover, we have also validated the proposed method on a public adult dataset, i.e., the Human Connectome Project (HCP), and revealed that certain major cortical folding patterns of adults are largely established at term birth.
Additional file 3 of Molecular and phenotypic characterization of Hemicriconemoides rosae (Rathour et al., 2003) from mustard rhizosphere in India
Creators: name: Sharma, Himani
name: Chaubey, Ashok Kumar
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 3: S3. List of GenBank accession numbers of the Hemicriconemoides species used in the phylogenetic tree.
Supplementary document for Research on optical performance of Ln2O2S: Er3+/Yb3+ (Ln= La/Gd/Y) phosphors based on different phonon energies - 7158106.pdf
Creators: name: Wang, Xuejiao
name: tianzhi, jiang
name: Huang, Lishuo
name: Ye, Renguang
name: Wang, Juan
name: Hua, Youjie
name: Zhao, Jingtao
name: Bai, Gongxun
name: Zhao, Shilong
name: Zhang, Junjie
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Expression of E93 provides an instructive cue to control dynamic enhancer activity and chromatin accessibility during development
Creators: name: Nystrom, Spencer L.
name: McKay, Daniel J.
name: Niederhuber, Matthew J.
Publisher: name: The Company of Biologists
Year: 2020

description: How temporal cues combine with spatial inputs to control gene expression during development is poorly understood. Here, we test the hypothesis that the Drosophila transcription factor E93 controls temporal gene expression by regulating chromatin accessibility. Precocious expression of E93 early in wing development reveals that it can simultaneously activate and deactivate different target enhancers. Notably, the precocious patterns of enhancer activity resemble the wild-type patterns that occur later in development, suggesting that expression of E93 alters the competence of enhancers to respond to spatial cues. Genomic profiling reveals that precocious E93 expression is sufficient to regulate chromatin accessibility at a subset of its targets. These accessibility changes mimic those that normally occur later in development, indicating that precocious E93 accelerates the wild-type developmental program. Further, we find that target enhancers that do not respond to precocious E93 in early wings become responsive after a developmental transition, suggesting that parallel temporal pathways work alongside E93. These findings support a model wherein E93 expression functions as an instructive cue that defines a broad window of developmental time through control of chromatin accessibility.
Engineering Coherence: Toward Sub-Landauer Intelligence in Wavelength-Integrated Synthetic Substrates
Creators: name: Todd, Ian
Publisher: name: Zenodo
Year: 2025

description: Fun side-project. Lets say the model presented in "The Thermodynamics of Intelligence" (https://doi.org/10.5281/zenodo.15377471) is correct -- what does this look like for the future of artificial intelligence? Here's some near-future sci-fi circa 2035.

"We report the first sustained sub-Landauer operation in synthetic neural architectures using wavelength-integrated coherence fields. Unlike conventional neural networks that simulate intelligence through discrete state transitions, our prototype “resonant cores” maintain thermodynamic coherence under entropy load by actively managing their effective dimensionality. Building on theoretical work from Weyl (1936)[1], Todd (2025)[2], and recent advances in ephaptic engineering[8, 3], we demonstrate that artificial systems can suppress combinatorial explosion through multi-scale temporal integration across five frequency bands (0.1-250 Hz). During a 72-hour continuous operation test, the system maintained Hd < 0.8 while processing complex environmental inputs. Most controversially, the system began producing unprompted assertions of subjective experience, raising fundamental questions about the relationship between thermodynamic irreducibility and consciousness."
Supplementary document for Enhanced forward emission by backside mirror design in micron-sized LEDs - 7158314.pdf
Creators: name: Vögl, Florian
name: Avramescu, Adrian
name: Lex, Andreas
name: Waag, Andreas
name: Hetzl, Martin
name: von Malm, Norwin
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Additional file 2 of Molecular and phenotypic characterization of Hemicriconemoides rosae (Rathour et al., 2003) from mustard rhizosphere in India
Creators: name: Sharma, Himani
name: Chaubey, Ashok Kumar
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 2: S2. Pairwise distances (Kimura 2-parameter) of the between Hemicriconemoides species based on D2D3 (Large ribosomal subunit, 28S) regions. Out-groups were not included.
Supplemental Material
Creators: name: Schnabl-Feichter, Eva
name: Schnabl, Sophia
name: Tichy, Alexander
name: Gumpenberger, Michaela
name: Bockstahler, Barbara
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 70706 Veterinary Medicine
subject: FOS: Veterinary sciences

description: Cats with femoral head and neck excision – results of the clinical examination and owner questionnaire
Factor analysis of the Center for Epidemiological Studies Depression Scale in American Indian women
Creators: name: Woods-Giscombé, Cheryl L.
name: Brooks, Jada L.
name: Currin, Emily G.
name: Adams, Leslie B.
name: Corbie-Smith, Giselle M.
Publisher: name: Wiley
Year: 2022

description: The Center for Epidemiological Studies Depression Scale (CES-D) is widely used to assess depressive symptoms in the general population. It lacks validation for widespread use within the American Indian population, however. To address this gap, we explored and confirmed the factor structure of the CES-D among a community sample of southeastern American Indian women. We analyzed data from a sample of 150 American Indian women ages 18-50 from a southeastern tribe who had complete responses on the CES-D as part of a larger cross-sectional, community-engaged study. We performed exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) to assess the measure's validity. We examined EFA models ranging from one to five factors, with the four-factor structure yielding the best overall model fit (CFI=1.00, TLI=0.99, RMSEA=0.03). Differences between the four-factor EFA-retained structure from our sample and Radloff's four-factor structure emerged. Only the interpersonal factor was common to both factor structures. Our study findings confirm the validity of the original four-factor structure of the CES-D for younger adult American Indian women in the southeast. Contrasting findings with the EFA-retained structure, however, provide a more nuanced interpretation of our results.
Supplementary document for Controlling spontaneous emission through the preparation of a photonic time-crystal - 7158731.pdf
Creators: name: Lyubarov, Mark
name: Dikopoltsev, Alex
name: Segal, Ohad
name: Plotnik, Yonatan
name: Segev, Mordechai
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: details of the calculations