cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Repository for Integrated Solar Energy in the Built Environment
Creators: name: McCarty, Justin
name: Waibel, Christoph
name: Schlüter, Arno
Publisher: name: ETH Zurich
Year: 2022
Subjects: ARCHITECTURE
BIPV
Urban energy modeling
Solar Energy

description: This repository serves as a collection point for buildings and infrastructure have integrated solar energy technologies, most prominently building integrated photovoltaics (BIPV). The repository can be explored through a map tool with basic filtering functionality. Along with the map explorer we have included a set of plots to explore the projects through their performance and inherent characteristics (i.e. type of project, annual yield, system efficiency, etc.). As the repository explorer   is expanded more projects will be included as well as resources for various audiences, such as design booklets for BIPV or reference materials for engineering standards.
M(otion)-mode Based Prediction of Cardiac Function on Echocardiograms
Creators: name: Sutter, Thomas M.
name: Balzer, Sebastian
name: Oezkan, Ece
name: Vogt, Julia E.
Publisher: name: ETH Zurich
Year: 2022
Subjects: Echocardiography
M-mode Ultrasound
Ejection Fraction

description: Early detection of cardiac dysfunction through routine screening is vital for diagnosing cardiovascular diseases. An important metric of cardiac function is the left ventricular ejection fraction (EF), which is used to diagnose cardiomyopathy. Echocardiography is a popular diagnostic tool in cardiology, with ultrasound being a low-cost, real-time, and non-ionizing technology. However, human assessment of echocardiograms for calculating EF is both time-consuming and expertise- demanding, raising the need for an automated approach. Earlier automated works have been limited to still images or use echocardiogram videos with spatio-temporal convolutions in a complex pipeline. In this work, we propose to generate images from readily available echocardiogram videos, each image mimicking a M(otion)- mode image from a different scan line through time. We then combine different M-mode images using off-the-shelf model architectures to estimate the EF and, thus, diagnose cardiomyopathy. Our experiments show that our proposed method converges with only ten modes and is comparable to the baseline method while bypassing its cumbersome training process.
Additional file 8: of Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength
Creators: name: Vihandha Wickramasinghe
name: Gonzàlez-Porta, Mar
name: Perera, David
name: Bartolozzi, Arthur
name: Sibley, Christopher
name: Hallegger, Martina
name: Ule, Jernej
name: Marioni, John
name: Venkitaraman, Ashok
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: PRPF8 depletion alters the dynamics of RNA splicing during transcription. a Raw data used to calculate co-transcriptional splicing ratio in Fig. 8a is shown. Normalized intron expression for first introns (fk, orange) and last introns (fI, blue) is shown for each independent depletion experiment (three for control siRNA, and four for PRPF8 siRNA). b The 5′ splice site strength of first and last introns are similar. The 5′ splice site strength was analyzed as described in “Materials and methods” for the first and last introns in the 2380 genes considered for the analysis of the co-transcriptional splicing ratio. The p value is indicated. c PRPF8 depletion alters the dynamics of RNA splicing during transcription. The kinetics of transcription and splicing recovery of the Separase gene following release from drug-induced transcriptional arrest were measured in control siRNA-treated and PRPF8-depleted cells in a similar fashion to that shown in Fig. 8d. (PDF 109 kb)
V2X-Enabled Control of Connected Vehicles Over a 5G Network
Creators: name: Pareth, Elias
Publisher: name: ETH Zurich
Year: 2022

description: Today’s research on automated driving systems shows a strong tendency to establish a more and more smartly connected environment. Communication between vehicles must be highly reliable and include low latencies to meet the stringent safety requirements of autonomous cars and the surroundings. The fifth generation (5G) networks will be the enabling technology to fulfill the challenging connectivity and serviceability demands of automated driving. This thesis studies the influence of different communication modes such as vehicle-to-vehicle (V2V), vehicle-to-infrastructure (V2I) and vehicle-to-everything (V2X) on safety augmentation and collective maneuver improvement for a platoon of vehicles that use the mentioned communication modes to exchange information between themselves and with the environment. A two-level feedback and feedforward control mechanism is proposed in this thesis, which takes into account the awareness of the other vehicles, or the surrounding states communicated through 5G-powered base stations, depending on the estimated reliability of the connections. We show the importance of communicating critical vehicle information/states such as position, velocity, brake status and slip ratio, and environment’s awareness such as road friction coefficient or road obstacles, in significantly improving safety margins of individual vehicles in comparison to the scenario where the control units solely rely on the on-board sensor measurements of their corresponding vehicle using, e.g., Radar, LiDAR or Camera. We present a comprehensive and modular simulation environment that is capable of accommodating the models for both communication and vehicle dynamic aspects of the platoon system. The communication system in the simulations is incorporated to match the stochastic/uncertain properties of a real-world communication system in terms of reliability and latency. The extensive simulation results directly demonstrate the difference between a connected and an isolated autonomous driving scenario and justify our propositions and claims for improving safety margins.
Additional file 2: of Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength
Creators: name: Vihandha Wickramasinghe
name: Gonzàlez-Porta, Mar
name: Perera, David
name: Bartolozzi, Arthur
name: Sibley, Christopher
name: Hallegger, Martina
name: Ule, Jernej
name: Marioni, John
name: Venkitaraman, Ashok
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology

description: Genome-wide decreases in spliceosome assembly at intron–exon junctions following PRPF8 depletion are independent of expression levels and intron retention. a, b Genome-wide decreases in spliceosome assembly following PRPF8 depletion are independent of expression levels. Spliceosome iCLIP plots around 5′ (a) and 3′ (b) splice site junctions were generated after excluding differentially expressed genes between the PRPF8-depleted and control siRNA-treated populations of cells from the analysis. c, d Spliceosome iCLIP plots around 5′ (c) and 3′ (d) splice site junctions were generated using the subset of retained introns (top panels) and the subset of non-retained introns (bottom panels) in control siRNA-treated and PRPF8-depleted cells. Relevant peaks around 5′ and 3′ splice site junctions that change in response to PRPF8 depletion are indicated by red arrowheads. (PDF 128 kb)
Additional file 1: of Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength
Creators: name: Vihandha Wickramasinghe
name: Gonzàlez-Porta, Mar
name: Perera, David
name: Bartolozzi, Arthur
name: Sibley, Christopher
name: Hallegger, Martina
name: Ule, Jernej
name: Marioni, John
name: Venkitaraman, Ashok
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Immunology
subject: FOS: Clinical medicine

description: Validation of PRPF8 depletion. a Validation of PRPF8 depletion by qRTPCR. Results are plotted relative to RNA levels in Control siRNA-treated cells, assigned an arbitrary value of 1, and show the mean of triplicate repeats from ten independent experiments ± standard error of the mean. b Exposure to the specific but not control siRNAs efficiently depletes PRPF8 protein in Cal51 cells as detected by western blotting with the indicated antibodies. c, d Characterization of spliceosome iCLIP experiments. UV-crosslinked Cal51 cells were lysed and subjected to partial RNase I digestion (low, final dilution of 1:100,000; high, dilution of 1:5000). Spliceosomal RNPs were immunopurified with anti-SmB/B’ antibody, RNA was 5′ end radiolabeled, and RNPs subjected to denaturing gel electrophoresis and nitrocellulose transfer, an autoradiogram of which is shown. Each lane represents an independent depletion experiment. The interrupted line indicates the area on the nitrocellulose membrane cut out for purification of crosslinked RNP complexes. e Library stats giving the ratio of unique cDNA counts to total cDNA counts for each of the libraries sequenced. The average from three experimental replicates and two technical replicates for each condition is indicated. (PDF 190 kb)
ValParCH: Integrating land use change, Ecosystem Service and Biodiversity modelling to simulate pathways towards a functioning Ecological Infrastructure for Switzerland
Creators: name: Black, Benjamin
name: Adde, Antoine
name: Külling, Nathan
name: Grêt-Regamey, Adrienne
name: Guisan, Antoine
name: Lehmann, Anthony
Publisher: name: ETH Zurich
Year: 2022

description: The ValPar.CH project commissioned by the Swiss Federal Office for the Environment (FOEN) will simulate the future development of Switzerland’s Ecological Infrastructure (EI) under multiple scenarios with the aim of exploring policy interventions intended to secure a functioning EI by 2060. Within the scope of ValPar.CH, EI is defined as a network of high quality natural and semi-natural landscape elements planned and managed to provide ecosystem services (ES) and support biodiversity. As such, simulating the development of EI is operationalized through the coupling of Land Use Land Cover Change (LULCC), ES provision and species distribution models. This coupling presents numerous practical challenges, one of which is a trade-off between model complexity and interoperability which is often exacerbated by the demand upon collaborating researchers to demonstrate innovation in their respective fields. On the other hand, it also raises conceptual questions regarding how to present the results of modelling multiple environmental phenomena in a unified, coherent manner. Whilst there can be no objective solutions to these issues, we demonstrate the approaches taken to address them within the ValPar.CH project. Specifically, we highlight how flexibility is essential in the selection of modelling approaches with key considerations for interoperability being: adaptability to a commonly agreed spatio-temporal resolution of analysis, maximisation of overlap between predictors/data sources, and the possibility to realise the models in open source programming applications, such as R and Python. Furthermore, we present how stakeholder participation can be used to derive a context specific indicator of EI combining components of ES, biodiversity and landscape metrics. Key words: model coupling; ecosystem service; species distribution; land use change; ecological infrastructure
Additional file 1: of Non-sedation versus sedation with a daily wake-up trial in critically ill patients recieving mechanical ventilation - effects on long-term cognitive function: Study protocol for a randomized controlled trial, a substudy of the NONSEDA trial
Creators: name: Nedergaard, Helene
name: Jensen, Hanne
name: Stylsvig, Mette
name: JĂ¸Rgen Lauridsen
name: Toft, Palle
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents. (PDF 130 kb)
Ex-ante identification of policy interventions to secure a functioning ecological infrastructure: A participatory Bayesian Network approach in Switzerland
Creators: name: Black, Benjamin
name: Grêt-Regamey, Adrienne
Publisher: name: ETH Zurich
Year: 2021

description: Assessing Ecological Infrastructure (EI) necessitates value judgements with respect to the importance of different components such as ecosystem services and biodiversity. As such it is crucial that assessments as well as the planning of policies to maintain EI incorporate the participation of relevant stakeholders. However, implementing this can be problematic as the quantification of EI typically involves modelling approaches that are in-transparent to nonexperts. Bayesian Networks (BNs) can overcome this by allowing for the integration of knowledge from closed form solutions and machine learning techniques with that from stakeholder elicitation. Furthermore, BNs allow for increased transparency of modelling processes through their representation as directed casual diagrams, with the possibility of spatially visualizing results including attendant uncertainties. These features allow for meaningful stakeholder participation in the simulation of EI thereby fostering increased stewardship. This research demonstrates this through a prototypical dynamic, spatially explicit, Bayesian Network (BN) incorporating stakeholder participation to simulate future EI in Geneva, Switzerland. First, stakeholder input informs the interactions of actors in the implementation of policies linked to EI conceptualized through Contextual Interaction Theory. This is operationalized alongside historical patterns to model future Land Use Land Cover change (LULCC) which in turn is used to predict future values of ecosystem service supply and biodiversity outcomes. Stakeholders then weight these outcomes into an aggregated measure of EI that reflects their views on the importance of each aspect. This participatory BN is first used in a forecasting capacity to simulate the impact of policy interventions against a business-as-usual scenario. Following this, backwards inference is utilized to identify pathways to securing stakeholder defined visions of a functioning EI. The results of both processes highlight the trade-offs that occur between different prioritizations of EI when attempting to optimize policy interventions to manage natural resources for the future.
Fejfarictis Bonis & Ekrt & Kunstmüllerová & Martínek & Rapprich & Wagner 2024, n. gen.
Creators: name: Bonis, Louis de
name: Ekrt, Boris
name: Kunstmüllerová, Lucie
name: Martínek, Karel
name: Rapprich, Vladislav
name: Wagner, Jan
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Carnivora
Viverravidae
Fejfarictis

description: Genus Fejfarictis n. gen.
urn:lsid:zoobank.org:act:6C4DB081-464C-4F28-A2E8-D505094FBAB6
TYPE SPECIES. — Fejfarictis valecensis n. sp.
ETYMOLOGY. — The new genus is named in honour of Professor Oldřich Fejfar, an outstanding Czech palaeontologist who devoted his life to the study of fossil mammals. He, among others, rediscovered and scientifically described the so-called “rodent from Valeč”. Ictis (ἴκτις) is an ancient Greek word for small mustelids, in scientific names commonly used for small carnivorans in general.
DIAGNOSIS. — Small aeluroid, elongate p4 with strong mesial and distal accessory cuspids, quite thick cingulid encircling distal margin, m1 with moderately high protoconid, paraconid edge mesially, lingually and slightly up directed, metaconid slightly distally shifted with respect to protoconid (visible in buccal view), talonid basined with two quite thick cristids, bi-rooted m2 with low cuspids and thick cristids.
description: Published as part of Bonis, Louis de, Ekrt, Boris, Kunstmüllerová, Lucie, Martínek, Karel, Rapprich, Vladislav & Wagner, Jan, 2024, New early aeluroid carnivoran (Mammalia, Carnivora, Feliformia) from the classical palaeontological locality Valeč, the Czech Republic, pp. 1-12 in Geodiversitas 46 (1) on page 4, DOI: 10.5252/geodiversitas2024v46a1, http://zenodo.org/record/10491250
Additional file 7: of Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength
Creators: name: Vihandha Wickramasinghe
name: Gonzàlez-Porta, Mar
name: Perera, David
name: Bartolozzi, Arthur
name: Sibley, Christopher
name: Hallegger, Martina
name: Ule, Jernej
name: Marioni, John
name: Venkitaraman, Ashok
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Enhancement of 3′ splice-site strength renders the CDC20 mini-gene resistant to PRPF8 depletion. a A mini-gene containing a full-length intron flanked by two exons within the CDC20 gene. This particular intron is retained following PRPF8 depletion as determined by RNA-sequencing experiments and the corresponding coverage plot is shown. The 3′ splice site encompassing the intron–exon boundary is weaker than the corresponding consensus sequence and the sequence of 3′ splice mutant constructs are indicated with changes marked in red. b, c Enhancement of 3′ splice site strength renders the CDC20 mini-gene resistant to PRPF8 depletion. PRPF8 depletion strongly suppresses removal of this intron in the CDC20 mini-gene (left panel). Strengthening of the polypyrimidine tract allows efficient removal of this intron from the CDC20 mini-gene in PRPF8-deficient cells (middle panel). Plots in (c) represent quantification of band intensity of spliced and unspliced product using ImageJ (NIH) and represent the mean percentage of spliced mRNA ± standard error of the mean from three independent experiments. Statistically significant pairwise comparisons are indicated (*p < 0.05, **p < 0.01). n.s. not significant, WT wild type. (PDF 135 kb)
Combining filter and embedded approaches to improve variable selection in land use change Cellular Automata models using Random Forests
Creators: name: Black, Benjamin
Publisher: name: ETH Zurich
Year: 2022
Subjects: land use change
cellular automata
predictor selection

description: Cellular Automata (CA) are a commonly used type of model to simulate future land use/cover (LULC) change by treating the landscape as a pixelated abstraction of cells of different LULC classes. These models predict the potential for change at a cellular level based upon statistically modelled relationships between historically observed class-class transitions and environmental, socio-economic and neighbourhood predictor variables. Over the last two decades the diversity and complexity of the techniques used for this transition modelling within CAs has grown considerably. However, regardless of the technique chosen, an area that is still given insufficient attention is the process of variable selection necessary to produce accurate, yet parsimonious, predictive models. This is partly due to the fact that simulating change in even a small number of LULC classes necessitates modelling a large number of transitions, alongside the possibility of different realisations of neighbourhood variables (focal extent and decay rate) which makes for a time-consuming process. This research contributes to this issue by presenting a novel two-stage variable selection procedure in the context of regionalized LULC transition modelling for Switzerland, utilizing the Random Forests (RF) algorithm. The first stage represents a filter method whereby predictors are grouped categorically, ranked using univariate regression models and then thinned on the basis of pairwise correlations. Following this, a model embedded approach, Guided Regularized RF, is used to reduce feature redundancy. We demonstrate how this approach not only provides parsimonious models, but is an efficient method for high dimensional calibration of neighbourhood predictors. Furthermore, when applied across spatial and temporal scales, the method provides useful insights into non-stationarity that can inform the development of the CA model in which the models are incorporated.
Characterising non-stationarity in predictive models of land use in Swiss mountain parks to inform scenarios for deliberative transformation
Creators: name: Black, Benjamin
name: Wicki, Sergio
name: Grêt-Regamey, Adrienne
Publisher: name: ETH Zurich
Year: 2022
Subjects: non-stationarity
concept drift
Random forests
land use change

description: Investigating pathways for the transformative adaptation of socio-ecological systems (SESs) frequently requires simulating the development of aspects of the system in both space and time, often into the future. In many cases this is achieved through the creation of predictive models which are calibrated and validated using historical data before being applied to generate future projections under the assumption of stationarity (i.e. that the relationships between the phenomena being modelled and its predictors are constant). Of course, this assumption is inherently flawed given that the calibration of models often highlights the presence of clear non-stationarity, for example between different historical periods, indicating systemic change within the SES. Instead of disregarding non-stationarity this research seeks to demonstrate how characterising it can be used to improve understanding of how a given SES has, and is changing, and thus inform planning for deliberative interventions to encourage transformative adaptation. Our research will demonstrate this in the context of modelling future Land Use and Land Cover (LULC) change scenarios for several alpine regional nature parks in Switzerland. Specifically, we use Random Forests supervised classification to statistically model the relationships between class-class LULC transitions and a wide set of environmental, socio-economic and neighbourhood predictor variables. Performing this modelling at a regional scale across multiple time periods allows for the identification of both spatial and temporal non-stationarity within the predictors of LULC transitions. This non-stationarity is characterised through two approaches. Firstly, through changes in the inclusion of predictors in LULC transition models as a result of the feature selection process (filtering to produce the most parsimonious set of predictors by minimising redundancy). Secondly, through changes in the partial dependence plots which visualise the relationships between predictors and the probability of LULC transitions. Such analysis provides insights into how the relationships between, socio-environmental factors and the likelihood of LULC transitions change over time and space, which should inform the development of scenarios of future LULC change for alpine parks in Switzerland. For example, comparing the degree of temporal non-stationarity exhibited across different LULC transitions, in combination with historical rates of LULC change (unit area per time period), could highlight which transitions are more ‘unstable’ and thus subject to greater uncertainty. This knowledge should be taken into consideration when devising scenarios based around interventions intended to elicit transformative change specifically related to these LULC transitions.
Additional file 5: of Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength
Creators: name: Vihandha Wickramasinghe
name: Gonzàlez-Porta, Mar
name: Perera, David
name: Bartolozzi, Arthur
name: Sibley, Christopher
name: Hallegger, Martina
name: Ule, Jernej
name: Marioni, John
name: Venkitaraman, Ashok
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Depletion of Complex B components that interact directly with PRPF8 recapitulate defects in mitotic progression. a Independent depletion of several different components of the three major spliceosome subcomplexes (A, B, and C) used in Fig. 4 was verified by qRT-PCR. Plots are relative to RNA levels in control siRNA-treated cells, assigned an arbitrary value of 1, and show the mean of triplicate readings from at least three independent experiments ± standard error of the mean. b Bar graph depicting time spent in mitosis, measured from nuclear envelope breakdown to anaphase, obtained from live-cell imaging of U2OS cells stably expressing GFP-tagged histone H2B and depleted of spliceosome subcomplexes (A, B and C). For simplicity, cells are classified as spending either less than 60 min in mitosis (black bars), or >60 minutes (red bars). c Percentage of mitotic cells depleted of spliceosome subcomplexes (A, B, and C) with defects in chromosome alignment and/or segregation, as shown in Fig. 4. (PDF 155 kb)
title: Dual N-Heterocyclic Carbene/Photoredox-Catalyzed Coupling of Acyl Fluorides and Alkyl Silanes
Creators: name: Jakob, Michael
name: Steiner, Luca
name: Göbel, Marius
name: Götze, Jan P.
name: Hopkinson, Matthew N.
Publisher: name: Freie Universität Berlin
Year: 2024
Subjects: subject: N-heterocyclic carbenes
subject: silanes
subject: photoredox catalysis
subject: ketones
subject: radicals
classificationCode: 540
subject: Chemie und zugeordnete Wissenschaften

description: The combination of N-heterocyclic carbene (NHC) organocatalysis with photochemical activation is becoming increasingly established as an approach for conducting radical organic reactions under mild and practical conditions. As comparatively easy to prepare and handle organic compounds, alkyl silanes are attractive substrates for radical chemistry as desilylative mesolysis of the corresponding radical cations is known to be rapid. Here, we report the successful application of benzyl silane derivatives as source of alkyl radicals in dual NHC/photoredox-catalyzed radical–radical coupling reactions with acyl fluorides. Relatively electron-rich benzyl silanes reacted smoothly to afford the corresponding ketones in generally good yields, while optimization of the NHC and photocatalyst allowed for a wider scope including primary benzyl substrates. Furthermore, initial experiments revealed that organosilanes bearing N-, O- and S-heteroatoms can also serve as alkyl radical sources under these conditions.
GIESEPP MP project webinars
Creators: name: WIT Berry
Publisher: name: Zenodo
Year: 2025
Subjects: electric propulsion
Propulsion System
Gridded Ion Engine
Ion thrusters
ion thruster

description: This document contains information about the webinars that were organised during the implementation of the GIESEPP MP project. They provide information on speakers, their presentations as well as links to the recorded presentations. 

Electric Space Propulsion & new career opportunities in the space sector in Europe (17.11.2021) 

 Electric space propulsion (24.05.2023) 

Unlocking Opportunities: Collaborating with Industry leaders in space sector (21.11.2023)

The final results Horizon 2020 project GIESEPP MP (20.11.2024)
Additional file 2: of Non-sedation versus sedation with a daily wake-up trial in critically ill patients recieving mechanical ventilation - effects on long-term cognitive function: Study protocol for a randomized controlled trial, a substudy of the NONSEDA trial
Creators: name: Nedergaard, Helene
name: Jensen, Hanne
name: Stylsvig, Mette
name: JĂ¸Rgen Lauridsen
name: Toft, Palle
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Original consent forms, in danish. (PDF 259 kb)
Additional file 1: of Perioperative chemotherapy in the treatment of osteosarcoma: a 26-year single institution review
Creators: name: G OâKane
name: K Cadoo
name: E Walsh
name: R Emerson
name: P Dervan
name: C OâKeane
name: B Hurson
name: G OâToole
name: S Dudeney
name: E Kavanagh
name: S Eustace
name: D Carney
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: Science Policy
subject: Plant Biology
subject: FOS: Biological sciences

description: Table S1. Chemotherapy protocol for resectable disease.
MOESM1 of Safe usage of cosmetics in Bangladesh: a quality perspective based on microbiological attributes
Creators: name: Rashed Noor
name: Nagma Zerin
name: Das, Kamal
name: Luthfun Nitu
Publisher: name: Figshare
Year: 2015
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Prevalence of pathogenic microorganisms in different types of cosmetics (cfuÂ gâ  1).
Additional file 1: Figure S1. of Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes
Creators: name: Sinead O’Sullivan
name: Gasparini, Fabrizio
name: Mir, Anis
name: Kumlesh Dev
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: (A) Soluble fractalkine levels are attenuated with ADAM10 inhibition following co-stimulation with TNF-α and IFN-γ. Astrocytes (grown in standard media) were pre-treated with the ADAM10 inhibitor (GI 254023X; 1 μM), for 30 min. Cells were then co-stimulated with TNF-α (1 ng/ml) and IFN-γ (1 ng/ml) for 18 h. Quantification of CX3CL1 ELISA revealed a significant decrease in soluble fractalkine when pre-treated with the ADAM10 inhibitor. ###p
Prediction of atmospheric parameters from GNSS observations and weather models with machine learning
Creators: name: Halbheer, Mike (Michelle)
Publisher: name: ETH Zurich
Year: 2021

description: Global Navigation Satellite Systems (GNSS) experience various delays as their signals propagate through the Earth’s atmosphere. Some sources of error, such as the ionospheric delay, can be accounted for with relative ease. Delays caused by the lowest atmospheric layer, the troposphere, however, are challenging to predict accurately due to their high spatial and temporal variability. Tropospheric delays depend on weather conditions, allowing the use of meteorological models as a basis for predictions. This thesis evaluates the capabilities of Recurrent Neural Networks (RNN) of the Long Short-Term Memory (LSTM) type for predictions of tropospheric parameters, using numerical weather models as inputs. As input parameters temperature, pressure, relative and specific humidity, precipitation, wind speeds and the geopotential are used. The proposed approach is able to achieve predictions with an average Root Mean Square Error (RMSE) of 0.8 centimeters for zenith dry delay and 3.0 centimeters for zenith wet delay, when compared to the original observations. They were carried out and evaluated for 145 stations across Europe. The utilized models can be transferred to other stations and retrained with significantly smaller datasets to achieve predictions of the same quality, enabling this approach to be applied to stations of interest without long timeseries.
Additional file 1 of Can Sierra Leone maintain the equitable delivery of their Free Health Care Initiative? The case for more contextualised interventions: results of a cross-sectional survey
Creators: name: FrĂŠdĂŠrique ValliĂ¨Res
name: Cassidy, Emma
name: McAuliffe, Eilish
name: Brynne Gilmore
name: Allieu Bangura
name: Musa, Joseph
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: Computational Biology

description: Household Survey Instrument. (PDF 481 kb)
MOESM5 of A nanobody:GFP bacterial platform that enables functional enzyme display and easy quantification of display capacity
Creators: name: Wendel, Sofie
name: Fischer, Emil
name: Martínez, Virginia
name: Seppälä, Susanna
name: Nørholm, Morten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 5: Table S1. Oligos used in this study.
MOESM1 of A nanobody:GFP bacterial platform that enables functional enzyme display and easy quantification of display capacity
Creators: name: Wendel, Sofie
name: Fischer, Emil
name: Martínez, Virginia
name: Seppälä, Susanna
name: Nørholm, Morten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Developmental Biology
subject: Cancer
subject: Hematology
subject: Plant Biology

description: Additional file 1: Figure S1. Cells expressing the NB-C-IgAP construct are negatively affected by induction of protein production. When induced with rhamnose of varying concentration, optical density of NB-C-IgAP cultures is decreasing drastically, and to a similar level independent of inducer concentration. LppOmpA-NB-producing cultures are also affected by induction, but less dramatically and in a stepwise manner. Values are normalised to the average of uninduced cells, biological triplicates, standard error.
MOESM2 of A nanobody:GFP bacterial platform that enables functional enzyme display and easy quantification of display capacity
Creators: name: Wendel, Sofie
name: Fischer, Emil
name: Martínez, Virginia
name: Seppälä, Susanna
name: Nørholm, Morten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Cancer
subject: Hematology

description: Additional file 2: Figure S2. Population distribution with the P trc promoter. The LppOmpA-NB fusion was cloned into a vector containing the IPTG-inducible P trc promoter and subsequently assayed according to the described NB:GFP procedure, followed by flow cytometry analysis. As depicted in the figure, a large majority of cells were fluorescent.
MOESM3 of A nanobody:GFP bacterial platform that enables functional enzyme display and easy quantification of display capacity
Creators: name: Wendel, Sofie
name: Fischer, Emil
name: Martínez, Virginia
name: Seppälä, Susanna
name: Nørholm, Morten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3: Figure S3. Variation in display signal when fusing OmpA-ChiA-NB to a set of 9 different signal peptides. The OmpA-ChiA-NB fusion protein was directed to the cell surface by different signal peptides, leading to varying levels of surface display. Values are averages of three biological replicates, error bars standard errors.
MOESM6 of A nanobody:GFP bacterial platform that enables functional enzyme display and easy quantification of display capacity
Creators: name: Wendel, Sofie
name: Fischer, Emil
name: Martínez, Virginia
name: Seppälä, Susanna
name: Nørholm, Morten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 6: Table S2. Plasmids used in this study.
MOESM4 of A nanobody:GFP bacterial platform that enables functional enzyme display and easy quantification of display capacity
Creators: name: Wendel, Sofie
name: Fischer, Emil
name: Martínez, Virginia
name: Seppälä, Susanna
name: Nørholm, Morten
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 4: Figure S4. Overview of plasmid construction. Oligos are given in bold font, plasmid names in regular font under the plasmid. Colours show from which source each fragment is amplified. The pK:LppOmpA-NB plasmid was made in several steps, starting with amplification of LppOmpA from the E. coli chromosome, whereas pK:C-IgAP was created in one step. The nanobody sequence was ordered as a G-block and restriction cloned into pGFP. Plasmids with Chitinase A were made by cloning of the ChiA gene into pK:LppOmpA-NB and pK:NB-C-IgAP. Details are found in Gene and Vector design in the Methods section.
Oiovelia spumicola Spangler
Creators: name: Floriano, Carla Fernanda Burguez
name: Rodrigues, Higor D. D.
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Veliidae
Oiovelia
Oiovelia spumicola

description: Oiovelia spumicola Spangler
(Figs. 2 E, 3, 4I, 5B)
Oiovelia spumicola Spangler, 1986: 438.
Material examined. All specimens macropterous. 2♂ and 1♀ (USNM), ‘ Venezuela. T. F. Amaz. \ Cerro de La Neblina \ Camp XI. 1450 m.\ 0º52’N. 65º 58’W \ 25–28 February 1985 ’ ‘ In mountain stream\ P.J. & P.M. Spangler \ & R. A. Faitoute’ ‘ Paratype \ Oiovelia \ spumicola \ PJSpangler’.
Discussion. This species is unique because it has not been recorded from other localities since its original description. Probably, it is restricted to elevations above 1,400 m on the border between southern Venezuela and northern Brazil. The apterous and macropterous forms were described by Spangler (1986), and later Rodrigues et. al. (2014) photographed the apterous form and illustrated the genital segments of the male. In this paper, we present for the first time photographs of the macropterous form (Fig. 3). Unlike other species of the genus, it does not have setae on the anterior lobe of the pronotum.
Distribution of the genus Oiovelia. Until now, the genus was recorded only from South America. The records of O. johnpolhemi sp. nov. from Mexico and Belize expand the occurrence of the genus to southern North America and Central America (Fig. 5 A). The absence of records in central South America (Figs. 5) is notable. Possibly, this distribution pattern is due to a deficit of sampling effort in this area. The same can be seen in southern Central America. Thus, new records and new species are expected to be discovered in both regions.
Oiovelia cunucunumana is the species with the largest distribution in the genus, occurring from northern Venezuela to northeastern Argentina. Oiovelia chenae Rodrigues & Melo, O. hamadae Rodrigues & Melo, O. pydanieli Rodrigues & Melo, and O. spumicola Spangler are probably species with Amazonian distribution. Out of these, O. pydanieli and O. spumicola are recorded only from the Guiana Shield. In contrast, O. brasiliensis Moreira, Nessimian & Rúdio, O. machadoi Rodrigues & Moreira, and O. viannai Rodrigues & Melo are species that occur on the east side of Brazil. The records for O. brasiliensis and O. machadoi are concentrated in the Atlantic Forest, whereas O. viannai is recorded from the Cerrado biome.
description: Published as part of Floriano, Carla Fernanda Burguez & Rodrigues, Higor D. D., 2016, A new species of Oiovelia (Heteroptera: Gerromorpha: Veliidae) from Mesoamerica, with an identification key to the genus, pp. 584-592 in Zootaxa 4144 (4) on page 591, DOI: 10.11646/zootaxa.4144.4.8, http://zenodo.org/record/272074
Gahrliepia (Gateria) bisetosa Mo 1970
Creators: name: Nielsen, David H.
name: Robbins, Richard G.
name: Rueda, Leopoldo M.
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Trombidiformes
Trombiculidae
Gahrliepia
Gahrliepia bisetosa

description: Gahrliepia (Gateria) bisetosa Mo, 1970:
ORI
Gateria (Gateria) bisetosa, Wen & Gui 2000
description: Published as part of Nielsen, David H., Robbins, Richard G. & Rueda, Leopoldo M., 2021, Annotated world checklist of the Trombiculidae and Leeuwenhoekiidae (1758 - 2021) (Acari: Trombiculoidea), with notes on nomenclature, taxonomy, and distribution, pp. 1-243 in Zootaxa 4967 (1) on page 24, DOI: 10.11646/zootaxa.4967.1.1, http://zenodo.org/record/4745510
Land motion in the Alps imaged by GNSS
Creators: name: Hübner, Laura
Publisher: name: ETH Zurich
Year: 2023

description: The densification of high-quality, permanent GNSS stations in Europe enables a large-scale investigation of deformation processes on the Earth’s surface. This project work aims to interpolate the horizontal and vertical GNSS station velocities and thus produce velocity fields showing the land motion for Switzerland, the Alps and Europe. The GNSS station velocities are provided by the EUREF Working Group on European Dense Velocities. The data set contains horizontal (east, north) and vertical velocities for around 8000 stations in Europe. Five interpolation methods are implemented and compared, namely, Inverse Distance Weighting (IDW), Ordinary Kriging, K- Nearest Neighbors (KNN), Random Forest and Multilayer Perceptron (MLP). Latitude and longitude of the station locations are used as input features for the interpolation. Generally, the performance of all five interpolation methods on the test data evaluated by Root Mean Square Error (RMSE), Mean Absolute Error (MAE) and Mean Bias Error (MBE) is comparable for all components in Switzerland, the Alps and Europe. RMSE and MAE vary among the methods by hundredths of a mm/year. The only exceptions are the horizontal velocity components for the extent of Europe, where MLP and Ordinary Kriging perform slightly worse than the other methods. MBE is one order of magnitude smaller than RMSE and MAE. The key findings of the qualitative analysis are that MLP and Ordinary Kriging produce the smoothest velocity fields, while IDW, KNN and Random Forest produce artifacts due to their mode of operation. All methods interpolate similar velocity fields where the station data is dense and greater differences when it is sparse. Especially for extrapolation areas where no data is available there is no possibility to verify their performance. The interpolation of the GNSS station velocities in Switzerland, the Alps and Europe for this project work shows that it is possible to produce velocity fields with accuracy on the sub-mm level and the different phenomena of land motion can be clearly identified.
Additional file 1: of A mother’s choice: a qualitative study of mothers’ health seeking behaviour for their children with acute diarrhoea
Creators: name: Cunnama, Lucy
name: Honda, Ayako
Publisher: name: Figshare
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Information for key informant interviews and focus group discussion. This supplementary information includes informed consent (verbal and written), as well as outlines for the key informant interviews and focus group discussions. (DOCX 21 kb)
Ethylene-to-propene (ETP) conversion over Ni(II) single sites on tailored silica-alumina supports
Creators: name: Chen, Zixuan
name: Docherty, Scott
name: Copéret, Christophe
name: Fedorov, Alexey
name: Müller, Christoph R.
Publisher: name: ETH Zurich
Year: 2022

description: Online Abstracts: 27th North American Catalysis Society Meeting
Additional file 1: of Nurse uniform wearing practices and associated factors among nurses working in Northwest Ethiopia: a cross-sectional institution based study
Creators: name: Etaferahu Desta
name: Mignote Gebrie
name: Berihun Dachew
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: English version questionnaire. (PDF 335Â kb)
Chemical looping oxidative dehydrogenation of ethane: Elucidating the role of alkali metal salt promoters to suppress overoxidation
Creators: name: Luongo, Giancarlo
name: Donat, Felix
name: Müller, Christoph R.
Publisher: name: ETH Zurich
Year: 2022

description: Online Abstracts: 27th North American Catalysis Society Meeting
The spatial distribution of causal factors behind the seismicity in the Delaware basin
Creators: name: Grigoratos, Iason
name: Savvaidis, Alexandros
name: Rathje, Ellen
Publisher: name: ETH Zurich
Year: 2022

description: Our analysis hindcasts seismicity rates of magnitude (M) ≥ 1.5 in the Delaware Basin (West Texas) from 2017 through 2019 on a 5km grid using either HF or SWD data as input, and compares them against the null hypothesis of solely tectonic loading. Each block is assigned a p-value, indicating the statistical confidence of its causal link with either HF, shallow SWD or deep SWD injection operations. To do that we expanded the framework of Grigoratos et al. (2020) to daily hydraulic fracturing (HF) operations and pressure-driven modeling of wastewater disposal (SWD). Our results indicate that 60% of the earthquakes occurred in blocks with p ≤ 0.05 (95% confidence interval) for at least one examined causal factor, and are thus triggered by oil and gas activities. This percentage increases to 68% for p ≤ 0.10 (90% confidence interval). Overall, more events than previously identified are associated with HF, especially within Reeves county. That said, shallow SWD is linked to more earthquakes, likely reactivating parallel faults of significant length. The seismicity around Pecos city seems to be affected by more than one injection activity, with higher frequency operational data and better depth resolution needed to fully decouple causality. Finally, within Culberson county, the only area where the earthquakes occur predominantly within the basement, the identified triggering mechanism is far-field SWD from deep wells.