LEDGF: Survival of Embryonic Chick Retinal Photoreceptor Cells
Creators: name: Singh, Dhirendra P.
name: Nakamura, Makoto
name: Kubo, Eri
name: Chylack Jr, Leo T.
name: Shinohara, Toshimichi
Publisher: name: Zenodo
Year: 2000
Subjects: immunohistochemistry
stress
LEDGF

description: Lens epithelium-derived growth factor (LEDGF) is a novel adhesive, survival, and growth<br> factor for lens epithelial cells, keratinocytes, fibroblasts, and cos7 cells. In the presence of LEDGF,<br> these cells acquire resistance to environmental stresses, and in the absence of LEDGF, they die. The<br> effects of LEDGF on the survival of embryonic chick retinal photoreceptor cells under serum starvation<br> and heat stress were studied.
description: From The Center for Ophthalmic Research, Brigham and Women's Hospital; and The Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts. Supported in part by NIH-sponsored RO1 project Grants EY10958, EY10824, and EY12015 (Bethesda, Maryland); Massachusetts Lions Eye Research Fund (Northborough, Massachusetts); and Shojin Research Associates fund (Studio City, California). Submitted for publication August 4, 1999; revised October 22, 1999; accepted November 16, 1999. Commercial relationships policy: N. Corresponding author: Toshimichi Shinohara, The Center for Ophthalmic Research, Brigham and Women's Hospital, 221 Longwood Avenue, Room 107, Boston, MA 02115. tshinohara@rics.bwh.harvard.edu
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