cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Investigating SMAD involvement in Transforming Growth Factor-beta signal transduction: identification, characterization and transcriptional regulation of Gadd45beta
Creators: name: Major, Michael Benjamin
Publisher: name: University of Utah
Year: 2012
Subjects: Cellular Signal Transduction
Genetic Transcription

description: Normal epithelial cells are in constant communication with their surrounding environment, largely through the detection, interpretation, and response to extracellular signaling molecules. The Transforming Growth Factor-beta (TGFbeta) supeifamily of growth factors comprises over 30 such signaling molecules in humans, many of which figure prominendy in development, tissue homeostasis and disease. Cells interpret the TGFbeta signal by integrating a multitude of signals into a cell type and context-dependent transcriptional profile. The transcripts comprising this profile are functionally responsible for the resulting phenotypic response, and consequently their identification and characterization is central to understanding TGFbeta in normal and diseased states. Therefore, we employed a global transcriptional profiling strategy to identify TGFbeta regulated genes in normal and cancerous tissues. This led to the cloning and characterization of Gadd45beta. We found that Gadd45beta transcriptional responsiveness to TGFbeta required the expression of the SMAD3 and SMAD4 transcription factors and the presence of a highly conserved 3-prime enhancer within the Gadd45p genomic locus. Using mammalian cell culture and zebrafish model systems, we discovered an essential role for Gadd45beta in the TGFbeta cytostatic program and metazoan development, respectively. Additionally, our expression screen led to the identification of the Kindlerin gene, a novel TGFbeta regulated gene involved in cell adhesion and spreading. In sum, our findings  provide  important  advancements  towards   understanding  how   normal   and  transformed cells interpret and respond to members of the TGPbeta family of cell signaling molecules.  work possible
Campomanesia xanthocarpa (Mart.) O. Berg essential oil induces antileishmanial activity and remodeling of the cytoplasm organelles
Creators: name: Ferreira, Fabiana Borges Padilha
name: Ramos-Milaré, Áquila Carolina Fernandes Herculano
name: Gonçalves, José Eduardo
name: Lazarin-Bidóia, Danielle
name: Nakamura, Celso Vataru
name: Sugauara, Rosangela Rumi
name: Fernandez, Carla Maria Mariano
name: Gazim, Zilda Cristiani
name: Demarchi, Izabel Galhardo
name: Silveira, Thaís Gomes Verzignassi
name: Lonardoni, Maria Valdrinez Campana
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Inorganic Chemistry
subject: Hematology
subject: 60506 Virology

description: Leishmaniasis is a neglected disease that affects millions of people worldwide. This study aimed to analyze antileishmanial activity of Campomanesia xanthocarpa leaf essential oil (EO) on promastigote and amastigote forms of Leishmania amazonensis, cytotoxicity in murine macrophages and sheep erythrocytes. The essential oil (EO) was analyzed by gas chromatography/mass spectrophotometry. The main and most abundant compounds were sesquiterpene hydrocarbons (71.22%) such as trans-caryophyllene (7.87%), bicyclogermacrene (11.28%), and δ-cadinene (8.34%). The IC50 for promastigote and amastigote forms of L. amazonensis was 70 µg mL−1 and 6 µg mL−1, respectively. C. xanthocarpa EO was not cytotoxic for murine macrophages (CC50 1860 µg mL−1) and sheep erythrocytes (1.5%), presenting high selectivity index for protozoan (310). C. xanthocarpa EO induced effects on the morphology and ultrastructure of this parasite. The high activity for intracellular amastigote forms, low toxicity to murine macrophages, and erythrocytes, suggest that C. xanthocarpa EO is promising for the treatment of leishmaniasis.
Onthophagus rubrescens Blanchard 1846
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Onthophagus
Onthophagus rubrescens

description: Onthophagus rubrescens Blanchard, 1846
Onthophagus rubrescens Blanchard 1846: 183 (Bolivia)
Distribution. Guyana: Bicknell et al. 2014: table S1. Suriname: Larsen 2011: 99, 2013: 97; MHCN; NZCS; RMNH. French Guiana: Boucomont 1932: 330; Feer 2000: 32; Feer and Pincebourde 2005: 29; Price and Feer 2012: 327; MHCN. “Guianas”: Balthasar 1941c: 353; Pulido Herrera and Zunino 2007: 114. Brazil (NA): Balthasar 1941c: 353; Vaz-de-Mello 2000: 194 (as O. (Onthophagus) rubrescens); Quintero and Roslin 2005: appendix A (as O. rubrecens [sic]) (NA); Pulido Herrera and Zunino 2007: 114; Gardner et al. 2008: table S1 (NA); Ratcliffe 2013b: 493 (NA). Venezuela (EO): Ferrer-Paris et al. 2013: 109 (EO). “Amazon Basin”: Boucomont 1932: 330. Other: Blanchard 1846: 183 (Bolivia); Gillet and Boucomont 1927: 208 (Bolivia); Boucomont 1932: 330 (Bolivia, Peru); Balthasar 1941c: 353 (Bolivia, Peru); Blackwelder 1944: 212 (Bolivia); Medina et al. 2001: 140 (Colombia); Pulido Herrera and Zunino 2007: 114 (Bolivia, Colombia, Peru).
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 92, DOI: 10.5281/zenodo.3678492
Regulation of steroid hormone action in lymphoid organs.
Creators: name: Hennebold, Jon Douglas
Publisher: name: University of Utah
Year: 2012
Subjects: Enzymes
Dehydrogenase

description: The neuroendocrine system regulates a variety of lymphoid cell activities through the actions of steroid hormones, including dehydroepiandrosterone (DHEA) and the glucocorticoids (GCS). This provides a linkage between the neuroendocrine and immune systems through the autocrine, paracrine, and endocrine acting substances that are produced. The studies in this thesis describe the mechanisms utilized by the lymphoid system to microenvironmentally control the immunomodulatory actions of DHEA and GCS in vivo. In the circulation, DHEA exists predominantly as the hydrophilic sulfated derivative dehydroepiandrosterone sulfate (DHEAS). The enzyme DHEAS sulfatase generates DHEA through the hydrolysis of the 3-beta-sulfate group. The DHEA that is formed from this enzymatic process is hydrophobic and effectively diffuses across cellular membranes. High levels of DHEAS sulfatase activity were observed within lymphoid organs, and predominantly associates with the macrophage. Stimulation of macrophages with a variety of microbial substances markedly inhibited the conversion of DHEAS to DHEA. Inhibition of enzyme activity was determined to be mediated by the actions of the macrophage synthesized cytokines TNF-alpha and IFN-alpha. Lymphoid organs were found to possess substantial levels of the enzyme 11-beta-hydroxysteroid dehydrogenase (11-beta-HSD). This enzyme interconverts the biologically active 11-hydroxy GCS to their biologically inactive 11-keto metabolites. Enzyme activity was found to vary within distinct lymphoid organs and associate with the immobile stromal elements. Physical and enzymological properties of the 11-beta-HSD activity present within lymphoid organs differed from the properties described for the two recently cloned and characterized 11-beta-HSD1 and 11-beta-HSD2 isoforms, suggesting the existence within these tissues of a novel 11-beta-HSD isoform. Inhibition of lymphoid organ 11-beta-HSD activity in vivo resulted in altered immune effector functions. This included a reduction in the production of activation inducible pro-inflammatory cytokines plus a depression in cell mediated immune responses. Similar effects are observed following the exogenous administration of GCS. These findings indicate that 11-beta-HSD within lymphoid organs and other tissues control the capacity of the GCS to function as immunomodulatory substances.
Identification Protocols For Analysis Of Aquatic Plants Imports (Ipaapi)
Creators: name: van Valkenburg, Johan
Publisher: name: Zenodo
Year: 2018
Subjects: Euphresco, aquatic import plants, invasive, quarantine, trade

description: Slide of Euphresco project 2016-A-184 'Identification protocols for analysis of aquatic plants imports (IPAAPI)'
Additional file 2 of Applying the intervention Complexity Assessment Tool to brief interventions targeting long-term benzodiazepine receptor agonist use in primary care: Lessons learned
Creators: name: Barry, Aisling
name: Lewin, Simon
name: Cadogan, Cathal A.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Additional file 2. Intervention complexity assessments based on the iCAT_SR tool.
Stress and symptoms of systemic lupus erythematosus.
Creators: name: Patton, Rita Colicchia
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Utah
subject: Nursing
subject: FOS: Health sciences

description: The purpose of this study was to identify and examine the relationship between a set a predictor variables and the criterion of physical and psychological symptoms manifested in patients with systemic lupus erythematosus (lupus).  The sample of 49 patients was obtained from the files of four physicians at the University of Utah Medical Center.  Each subject was asked to complete a demographic data sheet, Sullivan's (1977) Utah Test Appraising Health (UTAH-IV), and Cattell's (1970) Sixteen Personality Factaor Questionnaire (16PF).  Of the 49 subjects, 44 were female with 5 males participating.  The average age was 35 years, average amount of education was 13.8 years, and average number of years of having the disease was 6 years.  Two multiple regression analyses were computed, regressing physical and psychological symptoms on the  number of reported stress events, severity of illness, amount of education, number of hospitalizations, and ego strength.  The multiple R indicated that the number of psychological symptoms and the reported stress events demonstrated the strongest relationship with the criterion of lupus symptoms.  Ego strength accounted for very little variance, while education made a modes contribution in an inverse direction.  The second equation computed indicated that with a criterion of psychological symptoms, the number of physical symptoms and ego strength were the strongest predictors, with ego strength showing a negative correlation.  Both the number of stress events and the number of hospitalizations made negligible contributions to the prediction of psychological symptoms.
Drucksachen und Formular-Spezimina
Creators: name: Zwilchenbart AG
Publisher: name: [s.n.]
Year: 1890

description: Enthält: 1 Geschäftszirkular über die Gründung der Aktiengesellschaft (1890). 5 Briefköpfe (A. Zwilchenbart, Martin Gasser & Co., New York; Amerikanisches Passage- & Bankgeschäft A. Zwilchenbart Firma-Inhaber Karl & Hans Imobersteg;  Zwilchenbart AG (2 Stück); Holland-Amerika Lijn Generalvertretung in Basel (1894-ca. 1934). 1 Contat de passage (undatiert, ca. 1890). 1 Fragebogen und Vertrag zwischen dem Reisebureau Columbia AG (Haus Zwilchenbart) und dem Hotel... (undatiert, ca. 1930, leer). 1 Couvert für Reisepapiere (undatiert, ca. 1890).
description: Deutsch
description: Verzeichnung=Description=Inventaire 2020 ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Martin Lüpold
A Descriptive survey of maternal protein status and the course and outcome of pregnancy.
Creators: name: Evans, Gail Crandall
name: Hasty, Jane Elizabeth
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Nutrition
subject: Nursing
subject: FOS: Health sciences

description: A descriptive survey of the Nutrition;al status of 27 pregnant women was conducted at Hill Air Force Base Hospital.  Socioeconomic survey, three day diet history and laboratory assessment of blood and urine parameters of protein were used to determine Nutrition;al status and were related to maternal and infant outcome variables.  The purpose of the investigation was to answer the following research questions. 1) What is the relationship between reported dietary intake of protein and calories and measurable laboratory parameters of protein during pregnancy?  2) What is the relationship between reported dietary intake of protein and calories and the course and outcome of pregnancy?  3) What is the relationship between measurable laboratory parameters of proteins and the course and outcome of pregnancy?  Pearson â€œrâ€, Chi Square and two tailed â€œtâ€ tests were used to compare data and answer the research questions.  The findings indicated a significant decrease in protein and calorie intake between the first and second trimesters (p=.05).  The third trimester reported calorie intake was below the mean in the literature.  The reported dietary intake of protein and calories correlated with the laboratory parameter of total protein level in the second trimester significant at the .05 level.  The other laboratory parameters failed to correlate significantly with reported dietary intakes.  Correlations were found between second trimester reported protein intake and the Ponderal Index of the infant (p=.05).  Second trimester reported protein intake also correlated with the fetal/placental weight ratio (p=.05).  Dietary intake failed to correlate significantly with any maternal or infant outcome parameter.  Protein parameters were correlated with infant outcome variables more frequently than with maternal outcome variables.  Second trimester blood urea nitrogen correlated with fetal/placental weight ratio (p=.05).  Third trimester albumin levels correlated significantly with placental weight (p=.01), infant weight and occipital-frontal circumference (p=.05).  The only maternal outcome variable that correlated with any laboratory parameter was second day postpartum hematocrit to third trimester sermon total protein (p=.01),  This was an inverse correlation, as the third trimester protein increased, postpartum hematocrit decrease.  There were no significant relationships between maternal complications in the antepartum, intrapartum, or postpartum period and any of the Nutrition;al parameters surveyed.
Effect of aging on the phenotype and function of bone marrow derived dendritic cells from BALB/c mice
Creators: name: Liu, Qing
Publisher: name: University of Utah
Year: 2012

description: Dendritic cells (DCs) represent the most efficient antigen-presenting cells to initiate primary T cell responses. It is now also appreciated that DCs, through direct cell-cell contacts or as a result of the activities of secreted cytokines, serve to regulate the nature of T cell responses (e.g., Thl or Th2). The present studies demonstrate that CDllc^ bone marrow derived DCs (BMDCS) from aged donors exhibit a phenotype that suggests a more activated basal state of maturation than found with CDllc^ BMDCs derived from young donors. In vitro, compared to BMDCs derived from young donors, BMDCs derived from aged donors exhibit a decreased capacity to capture antigen, but increased abilities to activate peptide-specific T cells following peptide pulsing. These same DC populations, however, appear to display a compromised ability to process native protein antigen and to regulate T cell responses. In vivo, using an injected polystyrene microsphere model, aged mice were found to have higher percentage of Bead^CDl Ic^ cells migrated into the draining lymph nodes after receiving the phagocytic maturation-inducing stimulus. However, fewer microspheres were found in DCs in the draining lymph nodes of aged mice than in DCs of young mice. In vitro, excesses in oxidative stress and exposure to IL-6 can impair the abilities of BMDCs derived from young donors to process and present protein antigen. The mechanisms responsible for this appear different from that exhibited by BMDCs derived from aged donors. Although the molecular mechanisms responsible for impairing the functions of DCs with aging are presently unclear, these studies suggest that some of the age-associated immune dysfunctions may be due to changes in DC functions, resulting in compromised abilities by DCs to initiate and regulate T cell responses.
Additional file 1 of Providing “a beam of light to see the gaps”: determinants of implementation of the Systems Analysis and Improvement Approach applied to the pediatric and adolescent HIV cascade in Kenya
Creators: name: Beima-Sofie, Kristin
name: Wagner, Anjuli D.
name: Soi, Caroline
name: Liu, Wenjia
name: Tollefson, Deanna
name: Njuguna, Irene N.
name: Ogutu, Emily
name: Gaitho, Douglas
name: Mburu, Nancy
name: Oluoch, Geoffrey
name: Mwaura, Peter
name: Cherutich, Peter
name: Oyiengo, Laura
name: John-Stewart, Grace C.
name: Nduati, Ruth
name: Sherr, Kenneth
name: Gimbel, Sarah
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Additional file 1. SAIA-PEDS Focus Group Discussion Question Guide.
Geschäftsbuch "apartenant à Andreas Zwilchenbart à Basle, voyages de 1830 à 1837"
Creators: name: Zwilchenbart AG
Publisher: name: [s.n.]
Year: 1830

description: Darin: Einzelne lose Einlagen. Text ganz hinten steht Kopf zu Fuss.
description: Deutsch
description: Verzeichnung=Description=Inventaire 2014 ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Sebastian Preher
The role of ubiquitin in ATP-dependent proteolysis.
Creators: name: Chin, David Tung-ball
Publisher: name: University of Utah
Year: 2012
Subjects: Metabolism
Proteins

description: Radiolabeled ubiquitin was introduced into HeLa cells by red cell-mediated fusion procedure. The nuclei contained two major labeled proteins, ubiquitin and protein A24. The cytosol contained ubiquitin and a series of ubiquitin-protein conjugates. When the cotransferred hemoglobin was denatured by phenylhydrazine, a series of prominent ubiquitin-globin conjugates appeared. The concentration of globin-ubiquitin conjugates was proportional to the rate of hemoglobin degradation. These results provide support for the hypothesis that the covalent attachment of ubiquitin to proteins signals proteolysis.  However, direct ubiquitin attachment to substrates does not appear to be mandatory for proteolysis. Guanidinated (G) proteins, which have blocked lysine residues, were used as potential substrates for ATP-dependent proteolysis in rabbit reticulocyte lysates. G-lysozyme was degraded by an ATP-dependent process, yet ubiquitin conjugation to this protein was not observed. In contrast, conjugates between ubiquitin and lysozyme were readily detected. A ubiquitin-free fraction of the lysate was obtained which degraded both G-lysozyme and lysozyme by an ATP-dependent process that was stimulated by ubiquitin. Neither ubiquitin nor ATP alone significantly stimulated the formation of labeled adducts in ubiquitin-free lysates incubated with the labeled proteins. When both ubiquitin and ATP were added to the reaction mixtures, G-lysozyme-ubiquitin conjugates were not observed; whereas, lysozyme-ubiquitin conjugates were readily detected. These observations cast doubt on the hypothesis that ubiquitin has a unitary role as a covalent marker in ATP-dependent proteolysis.
Gelatin-based coating enriched with blueberry juice preserves the nutraceutical quality and reduces the microbial contamination of tomato fruit
Creators: name: Frassinetti, Stefania
name: Castagna, Antonella
name: Santin, Marco
name: Pozzo, Luisa
name: Baratto, Irene
name: Longo, Vincenzo
name: Ranieri, Annamaria
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Plant Biology

description: To preserve quality and extend the shelf life of tomato, a bioactive edible coating was prepared using gelatin wastes from pharmaceutical industry and lyophilised blueberry juice (BJ). The effectiveness of gelatin-coating (G) and G enriched with blueberry juice (GB) was tested, monitoring carotenoids, polyphenols and flavonoids content, the antioxidant activity and the antimicrobial efficiency of coating against the native microflora. After 7 d of storage, coated fruit showed higher phenolic and flavonoids content and increased antioxidant activity, while carotenoids were unaffected by the treatments. The growth of mesophilic bacteria of GB, and the growth of coliform bacteria of G and GB were significantly reduced during the entire period. The results indicate that GB preserved the nutritional quality of tomatoes and that BJ was able to increase the antimicrobial activity of the coating. This paves the way for a possible use of this biodegradable waste polymer as an eco-friendly coating material.
Brief an [Johannes II] Buxtorf
Creators: name: Le Clerc, David
Publisher: name: [s.n.]
Year: 1628

description: von David le Clerc
description: Schwarzes Siegel
description: Französisch
description: Verzeichnung=Description=Inventaire November 2012 Vollständige Rekatalogisierung nach Standortverzeichnis G I 1-70 und Briefkatalog
description: Digitalisierung=Digitization=Numérisation November 2021 TIFF
Onthophagus xanthomerus H. W. Bates 1887
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Onthophagus
Onthophagus xanthomerus

description: Onthophagus xanthomerus H. W. Bates, 1887
Onthophagus xanthomerus H. W. Bates 1887a: 69 (Brazil)
Distribution. French Guiana: Feer 2000: 32; Feer and Pincebourde 2005: 29; Brûlé et al. 2014: 183. Brazil: H. W. Bates 1887a: 69; Blackwelder 1944: 212; Vaz-de-Mello 2000: 194 (as O. (Onthophagus) xanthomerus); Pulido Herrera and Zunino 2007: 119. Venezuela: Boucomont 1932: 322 (as O. clypeatus var. xanthomerus). Other: Gillet and Boucomont 1927: 208 (South America); Boucomont 1932: 322 (Bolivia, Peru, Trinidad and Tobago - as O. clypeatus var. xanthomerus); Balthasar 1941c: 352 (Peru - as O. clypeatus forma xanthomerus); Medina et al. 2001: 140 (Colombia); Pulido Herrera and Zunino 2007: 119 (Colombia, Ecuador, Peru).
Note. For information regarding the validity of the name Onthophagus xanthomerus, see the note at O. clypeatus.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on pages 92-93, DOI: 10.5281/zenodo.3678492
Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activity in vitro and in silico
Creators: name: Liu, Shun-Zhi
name: He, Feng-Ming
name: Bin, Yan-lin
name: Li, Chu-Fang
name: Xie, Bao-Ying
name: Tang, Xi-Xiang
name: Qiu, Ying-Kun
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Penicillium polonicum MCCC3A00951 is a fungus with influenza neuraminidase (NA) inhibition activity derived from a sediment of the mangrove forest of Zhangjiangkou in Fujian province, China. Chemical investigation on an ethyl acetate extract of its fermentation led to the isolation of a new compound, 7-hydroxy-3,10-dehydrocyclopeptine (1), and 13 known compounds (2–14). The new compound was comprehensively characterised by high-resolution electrospray ionisation-mass spectrometry, and 1D, 2D nuclear magnetic resonance (NMR) spectra. The anti-influenza NA assay was performed to evaluate the potential biological activity. Surprisingly, Cyclopenin (2) showed potent influenza NA inhibition with an IC50 value of 5.02 μM. Besides, molecular docking simulation was performed to investigate the binding model of cyclopenin (2) with influenza NA. Consequently, cyclopenin (2) could be further optimised to be a potential anti-influenza NA candidate.
Computational fluid dynamics simulation study on hot spot location in a longwall mine gob
Creators: name: Lolon, Samuel Atta
Publisher: name: University of Utah
Year: 2012
Subjects: Coal mines
Mine ventilation
Mine safety

description: Spontaneous combustion is one of the main sources for mine fires in underground  coal mines. Most of these fires are initiated in the longwall gob (caved area) by coal  oxidation. Because coal oxidation generates heat, this phenomenon is called the selfheating  process. This process will eventually create hot spots under conditions, i.e.,  oxygen concentrations of at least 5% (by volume) and gob temperatures of 100°C. Coal  properties, gob permeability, self-heating characteristics, and the ventilation system are  the key variables for the formation of these hot spots.  A study was carried out to identify the location of hot spots. The study is based on  mine ventilation surveys, laboratory experiments, and gob simulations using  Computational Fluid Dynamics (CFD). Ventilation surveys were conducted in an existing  longwall mine located in the western United States; the laboratory experiments were  performed on a physical gob model to investigate permeability (k) and airflow  distribution; and the CFD models were simulated to investigate the flow behavior in the  gob, the oxidation of coal, and heat transfer phenomena. Four CFD models were  formulated and solved, three utilized a bleeder ventilation system, and the fourth a  bleederless ventilation system. For these models, the gob length varied from 912 m to  2,445 m. The gob of each model was divided into 3 zones of different permeability:  unconsolidated (k = 4.68 xlO"7 m2), semi-consolidated (k= 3.15 x 10"8 m2), and  consolidated (k = 7.98 x 10"9 m2).  The simulation results showed that in the models ventilated by a bleeder system,  the hot spot was located in the consolidated zone near the return side of the gob. Once  initiated, it propagated along the tailgate side as the gob progressed. The leakage flow  through the gob played an important role in determining the size and location of the hot  spot. In models ventilated by a bleederless system, the hot spot was located in the gob by  the face line. This is mainly caused by the air leakage from the headgate T junction (face)  and between the shields. It may extend further into the gob depending on the gob  permeability and the fan pressure.  In addition, these gob simulation exercises have shown that the hot spot areas in  all cases can be located accurately. This information can be used to develop suitable  control methods. The parametric studies have indicated that the ventilation system and  gob permeability are the major contributing factors for the formation of hot spots.  Although the gob models were developed for specific dimensions and ventilation system,  the results can be applied to other schemes with minor adjustments.
Phanaeini Hope 1838
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae

description: PHANAEINI Hope, 1838
Note. The subtribe Gromphina Zunino, 1985 is eliminated by Bouchard et al. (2011: 245) but resurrected by Cupello and Vaz-de-Mello (2013: 441) under the corrected spelling Gromphadina.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 93, DOI: 10.5281/zenodo.3678492
Красная книга Костромской области. Интерактивная карта на сайте florako.ru
Creators: name: Анна Александровна Ефимова
Publisher: name: Zenodo
Year: 2020

description: Интерактивная карта содержит информацию о местонахождениях (геоточках) охраняемых видов растений Костромской области. Она позволяет фиксировать данные мониторинга, выявлять охраняемые растения на определённом участке, смотреть распространение конкретного вида на территории области, получать общую информацию о каждом охраняемом виде.
Additional file 2 of Providing “a beam of light to see the gaps”: determinants of implementation of the Systems Analysis and Improvement Approach applied to the pediatric and adolescent HIV cascade in Kenya
Creators: name: Beima-Sofie, Kristin
name: Wagner, Anjuli D.
name: Soi, Caroline
name: Liu, Wenjia
name: Tollefson, Deanna
name: Njuguna, Irene N.
name: Ogutu, Emily
name: Gaitho, Douglas
name: Mburu, Nancy
name: Oluoch, Geoffrey
name: Mwaura, Peter
name: Cherutich, Peter
name: Oyiengo, Laura
name: John-Stewart, Grace C.
name: Nduati, Ruth
name: Sherr, Kenneth
name: Gimbel, Sarah
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Additional file 2. SAIA-PEDS In-Depth Interview Question Guide.
12 Briefe, 3 Beilagen an Salomon Escher [vom Glas]
Creators: name: Lavater, Johann Caspar
Publisher: name: [s.n.]
Year: 1759

description: von Johann Caspar Lavater
description: Davon 3 Briefe undatiert (Nr. 1-3); bei 1 Brief Datierung (Tag) unsicher wegen Beschädigung (Nr. 4)
description: Beilagen: gedruckter Zirkularbrief "An meine Freunde" mit eigenhändiger Unterschrift Lavaters, dreifach vorhanden, dat. gemäss anderem Exemplar Oktober 1795, vgl. FA Hess (1741) 181ac.114a (Nr. 13-15)
Geology of the Cedar Mountains Tooele County, Utah Part1
Creators: name: Maurer, Robert E.
Publisher: name: University of Utah
Year: 2012

description: The writer wishes to express his sincere gratitude to Dr.Daniel J. Jones for helpful comments regarding problems of the field work, for critical reading and suggestions in preparation of the manuscript, and for many valuable suggestions during the course of the study. Dr. W. Lee Stokes identified most of the brachiopods in addition to criticizing the manuscript. Professors A. J. Eardley, Max P. Erickson, and R. E. Marsell read the manuscript and offered valuable criticism. Dr. Grant Steel offered helpful advice concerning the recognition of units of the Park City and Phosphoria Formation and identified the major portion of the fusulinids. George Herman gave valuable assistance in securing identification of fusulinids and identified other foraminifera that the writer collected from the lower Great Blue Formation. Dr. Aurele LaRocque kindly identified gastropods collected by the writer from the North Horn (?) and the "Tertiary unnamed formation". The writer thanks Ralph J. Roberts for a number of helpful suggestions during several visits to the Cedar Mountains.
Jahresberichte 1977-1986
Creators: name: Basler Handelskammer
Publisher: name: [s.n.]
Year: 1977

description: Enthält: In Bände gebundene Hefte
description: Deutsch
description: Verzeichnung=Description=Inventaire 13.07.2017 Automatisiert nach HAN-Import
description: Verzeichnung=Description=Inventaire ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert
description: Verzeichnung=Description=Inventaire 2019 ISAD(G) / HAN Katalogisierungsregeln für Archivbestände Detailliert Martin Lüpold
Gromphas Brulle 1837
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Gromphas

description: GROMPHAS Brullé, 1837
Gromphas Brullé 1837: 304
Synopsis. Cupello and Vaz-de-Mello 2013, 2014
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 93, DOI: 10.5281/zenodo.3678492
8 Briefe an Paulus Usteri
Creators: name: Lavater, Johann Caspar
Publisher: name: [s.n.]
Year: 1764

description: von Johann Caspar Lavater
description: Lavater: von Zürich, Pfarrer an der St. Peters Kirche in Zürich, Dichter, Schriftsteller, Physiognomiker
description: Davon 1 Brief an Susette Hirzel (ab 1801 verh. Ott), dat. Zürich, 14.6.1792 (Nr. 10), 1 Brief an Chorherr Johannes Geßner, dat. Barth, 15.1.1764, mit Notiz von Unbekannt (Nr. 12), 1 Brief an Unbekannt (enthält die Schilderung seines Besuchs bei Karl, Prinz von Hessen-Kassel), dat. Schleswig, 13.6.1793 (Nr. 13)
description: Davon 1 Empfehlungsschreiben von Lavater für Usteri gerichtet an Freunde Lavaters (Nr. 6)
description: Dabei 2 Briefe von Johann Heinrich Füssli, dat. Bern, 11.7.1802, und Zürich, 26.4.1800 (Nr. 1 und 4), 1 Brief von Jules Muret, dat. Morges, 21.4.1802 (Nr. 2), 1 Brief von Bernhard Friedrich Kuhn?, dat. 7.3.1802 (Nr. 3), 1 Brief von Joseph Anton von Balthasar, dat. Luzern, 4.4.1798 (Nr. 5) an Usteri
description: Dabei Liste von Kontakten in Stuttgart, Ludwigsburg, Strassburg und Tübingen, dat. 21.3.1791 (Nr. 14-15); Politischer Bauren Catechismus für die Landschaft der Stadt Zürich von Hrn Jacob Bodmer Historiæ Patriæ Professore (Nr. 16)
Aerial alchemy
Creators: name: James, Jan
Publisher: name: University of Utah
Year: 2013
Subjects: Alchemy in art

description: This is a final project paper based on the use of alchemic fundamental practices to explore contemporary symbols, dynamic opposites and elements representing our transformative time. By uniquely combining these elements, color, mediums and techniques into an imagined space, I hope to deliver something rare and precious to the viewer.
1 Brief an [N.N.]
Creators: name: Lavater, Johann Caspar
Publisher: name: [s.n.]
Year: 1783

description: von [Johann Caspar] Lavater
description: Über die Verwendung eines restlichen Guthabens (1 Reichstaler, abzüglich Briefporto, Erstattung entweder in Form einer weiteren Arznei oder für die Armen)
description: Dabei: 1 Portrait Lavaters
12 Briefe, 9 Umschläge an [Johann] Kaspar Horner
Creators: name: Lavater, Johann Caspar
Publisher: name: [s.n.]
Year: 1798

description: von Johann Kaspar Lavater
description: Davon 10 Empfehlungsschreiben von Lavater für Horner an Diethelm Lavater, Generalsuperintendent Josias Friedrich Christian Löffler, Georg Friedrich Seiler, Johann Gottlieb Fichte, Johann Christoph Karg, Heiligenvogt Johannes Vosseler, Heinrich Eberhard Gottlob Paulus, Christoph Martin Wieland, Johann Gottfried von Herder, Jean Paul (Nr. 3-12), davon 6 in ungeöffneten Umschlägen (Nr. 5-6 und 8-11)
description: Eine Kopie von Nr. 1 findet sich unter FA Lav Ms 566.65
Additional file 1 of Gait biofeedback training in people with Parkinson’s disease: a pilot study
Creators: name: McMaster, Kate
name: Cole, Michael H.
name: Chalkley, Daniel
name: Creaby, Mark W.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Sociology
subject: FOS: Sociology

description: Additional file 1. Participant flow through the study.
Nobody's money : introducing choice-card, an innovative and comprehensive approach to the financing of health care
Creators: name: Poulsen, Alden Lloyd
Publisher: name: University of Utah
Year: 2012
Subjects: Medical care, Cost of - United States
Medical care - United States - Cost control

description: The need to attempt some type of control on the cost of medical care has become rather generally accepted.  What hasn't been agreed upon how this will be done in the long term.  The current means of attempting control without the need of significant government intervention is the pro-competitive environment which is initiating sweeping changes, and is showing some early promise of reducing the rapidity of medical cost increase.  Prepaid medical care is being emphasized as hold the key to this problem.  In these systems we are relying on the physician to be both provider and rationer of care while entitling the patient to all "necessary" medical care.  The patients have for many years been conditioned by  the medical system to a perception of necessary medical care.  The medical profession, however, is not as readily able to define necessary care, but has been given the responsibility to deliver it.  As these new systems increase, an adversarial role is developing between doctor and patient.  From the vantage point of nearly 25 years as a family physician, studying the response of patient and provider to the incentives of the system; the author has formulated a unique system of medical care financing.  This system will employ a voucher concept, cost-effective incentives built in the reimbursement structure for both physician and patient.  It provides for a maximum of patient choice as the patient and his physician work as a partnership to define and obtain necessary medical care.  This concept is explained; logic for its  theoretical basis is given.  It is analyzed from the standpoint of the principles of the Health Policy Agenda for the American People and in view of cost containment and health policy literature. Some suggestions of possible approaches to implementation are also made.
Cytotoxic potential of the Red Sea sponge Amphimedon sp. supported by in silico modelling and dereplication analysis
Creators: name: Shady, Nourhan Hisham
name: Abdelmohsen, Usama Ramadan
name: AboulMagd, Asmaa M.
name: Amin, Mohamed N.
name: Ahmed, Safwat
name: Fouad, Mostafa A.
name: Kamel, Mohamed Salah
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified

description: The chemical profile of the butanol fraction of the Red Sea sponge Amphimedon sp. was explored using liquid chromatography coupled with high-resolution mass spectrometry and identified compounds (1–11). Moreover, cytotoxic activities of the total extract and other fractions were examined against three cell lines HEPG2, MCF7 and CACO2, revealed the powerful effect of the total extract and the butanol fraction against the three cell lines. Further chromatographic separation of the active butanol fraction yielded the isolation of three known compounds (9–11). Molecular modelling was carried out with the active site of the SET protein. Docking study results revealed that amphiceramides A-B (7–8) and acetamidoglucosyl ceramide (6) showed the highest energy binding affinities and interaction in the binding site of SET protein. Additionally, ADME/Tox calculations were performed for the compounds to predict their pharmacokinetics profile. These results highlighted the valuable chemical entities of Amphimedon sp. as lead source for cytotoxic natural products.
Gromphas aeruginosa
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Gromphas
Gromphas aeruginosa

description: § Gromphas aeruginosa (Perty, 1830)
Onitis aeruginosus Perty 1830: 39 (Brazil)
Distribution. “Guianas”: Vulcano and Pereira 1967: 566. Brazil (NA): Perty 1830: 39 (Onitis aeruginosus); Olsoufieff 1924: 58; Balthasar 1941c: 350; Blackwelder 1944: 208; Barattini and Saenz 1964: 177; Vaz-de-Mello 2000: 193; Figueroa et al. 2012: 3; Cupello and Vaz-de-Mello 2013: 448 (NA), 2015: 954. Venezuela: Olsoufieff 1924: 58; Balthasar 1941c: 350; Barattini and Saenz 1964: 177; Vulcano and Pereira 1967: 566; Hamel-Leigue et al. 2009: 61; Figueroa et al. 2012: 3. “Amazon Basin”: Gillet 1911b: 80; Vulcano and Pereira 1967: 566. Other: Olsoufieff 1924: 58 (Bolivia, Colombia, Peru); Balthasar 1941c: 350 (Bolivia, Colombia, Peru); Blackwelder 1944: 208 (Bolivia); Barattini and Saenz 1964: 177 (Bolivia); Vulcano and Pereira 1967: 566 (Bolivia); Medina et al. 2001: 138 (Colombia); Hamel-Leigue et al. 2009: 61 (Bolivia, Colombia, Peru); Figueroa et al. 2012: 3 (Bolivia, Colombia, Peru); Cupello and Vaz-de-Mello 2013: 448 (Bolivia, Colombia, Ecuador, Peru), 2015: 954 (Bolivia, Peru).
Note. The report of Gromphas aeruginosa from the Guianas in Vulcano and Pereira (1967: 566) is probably incorrect according to Cupello and Vaz-de-Mello (2013: 448). We suspect that at least part of the records from Venezuela concerns G. lemoinei, which has been considered a variety of G. aeruginosa in for example Gillet (1911b: 80) and Blackwelder (1944: 208). Based on records from locations north of the Amazon in the Brazilian states of Amazonas and Pará as mentioned in Cupello and Vaz-de-Mello (2013), we still regard G. aeruginosa as potentially occurring in the Guianas.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 93, DOI: 10.5281/zenodo.3678492
5 Spruchkärtchen an Maria Barbara Heß-Schultheß
Creators: name: Lavater, Johann Caspar
Publisher: name: [s.n.]
Year: 1795

description: von [Johann Caspar] L[avater]
description: Davon 1 Spruchkärtchen undatiert
description: Dabei: 3 Briefe an N.N. (weibl. Adressatinnen, einer davon an B.W., vrmtl. Barbara Hess-Wegmann), dat. 1.1., 26.5. und 3.9.1799; 2 Spruchkärtchen an einen Freund nach meinem Tode, dat. 9.9. und 13.9.1794; 1 Spruchkärtchen an N.N., dat. Erlenbach, 25.7.1800; 3 Spruchkärtchen zu den Stichworten Berufstreue (dat. 31.8.1796), Religion und Suche (beide dat. 24.8.1796); 7 Portraits von Lavater, davon eines zusammen mit seinem Sohn Johann Heinrich; 2 Vignetten
Hyrtioscalaranes A and B, two new scalarane-type sesterterpenes from Hyrtios erectus with anti-inflammatory and antioxidant effects
Creators: name: Chakraborty, Kajal
name: Francis, Prima
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Two new scalarane-type sesterterpenes, hyrtioscalaranes A and B, were isolated from the organic extract of the Demosponge Hyrtios erectus through extensive chromatographic purification. Hyrtioscalarane A exhibited significantly greater attenuation property against cyclooxygense-2 (IC50 0.83 mM) than that displayed by hyrtioscalarane B (IC50 0.98 mM). The greater selectivity index of hyrtioscalaranes (> 1) than that exhibited by the commercial anti-inflammatory agent ibuprofen (0.43) further supported the higher selectivity of the former towards pro-inflammatory cyclooxygenase-2. Hyrtioscalarane A exhibited greater antioxidant activities as determined by 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (IC50 0.77 mM) and 2,2-diphenyl-1-picrylhydrazyl (IC50 0.81 mM) free radical quenching properties than those displayed by hyrtioscalarane B (IC50 > 0.83 mM) and the antioxidative agent α-tocopherol (IC50 1.51 mM). The greater binding energy (–14.32 kcal/mol) and docking score (15.22 kcal/mol) of hyrtioscalarane A at the active site of cyclooxygenase-2 along with the higher electronic parameters and balanced hydrophobicity could attribute its potential anti-inflammatory activity.
In the house of beauty
Creators: name: Rogers, Erin
Publisher: name: University of Utah
Year: 2012
Subjects: Experimental writing
Fiction
Mythology
Non-fiction
Religion
Women's studies

description: This collection of short fiction was written to explore the limits of genre, the page, and language itself. It is an exploration and discovery of space. A peek into the in between. An examination of the unknown, the negative, the experiences that never were. It is a contradiction. A fleeting moment in time. A depiction of creation.  Reined into four separate sections, this collection interweaves stories of the body and self, worship and betrayal, the domestic, and the undiscovered. Fiction becomes nonfiction becomes lyric becomes prose again. These stories seek to expose the nerves of  language. Here words are seduction, negation, collision. The mouths that speak are those of gods and the dead, children and lovers, aviators and prophets.  In the house of beauty language may dart across the page, slow into columns, or rest atop an image. This collection means to examine the material reality of a page: white space, alignments, order and categorization. Some pieces collage together found text;, illustrations, or photographs to re-examine how image and text; collide on a page.  The last section contains video / text; pieces that exist outside the space of the page. These videos attempt to further explore the experience of reading. To confront and challenge the linear idea of time, to make the familiar strange. A piano key. A bare lightbulb. The blinking heart of the elevator light. The very appearance of words themselves.   Knock and it will answer.
Gromphas amazonica H. W. Bates 1870
Creators: name: Hielkema, Auke J.
name: Hielkema, Meindert A.
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Scarabaeidae
Gromphas
Gromphas amazonica

description: § Gromphas amazonica H. W. Bates, 1870
Gromphas amazonicus H. W. Bates 1870: 175 (Brazil - LECTOTYPE)
Distribution. French Guiana: Olsoufieff 1924: 59 (?). Brazil (NA): H. W. Bates 1870: 175 (as Gromphas amazonicus); Olsoufieff 1924: 59; Blackwelder 1944: 208; Vaz-de-Mello 2000: 193; Figueroa et al. 2012: 3; Cupello and Vaz-de-Mello 2013: 462 (designation LECTOTYPE Gromphas amazonicus) (NA), 2015: 946. “Amazon Basin”: Gillet 1911b: 80. Other: H. W. Bates 1870: 175 (Peru - as Gromphas amazonicus); Olsoufieff 1924: 59 (Argentina?, Peru); Figueroa et al. 2012: 3 (Colombia, Peru); Cupello and Vaz-de-Mello 2013: 462 (Colombia, Peru), 2015: 946 (Colombia, Peru).
Note. The only record of Gromphas amazonica for the Guianas that we are aware of is given in Olsoufieff (1924: 59), who mentions a specimen purportedly coming from French Guiana but casts doubt on the veracity of that origin. As Cupello and Vaz-de-Mello (2013: 462) record this species from the state of Amapá in Brazil, we regard it as potentially occurring in the Guianas.
description: Published as part of Hielkema, Auke J. & Hielkema, Meindert A., 2019, An annotated checklist of the Scarabaeoidea (Insecta: Coleoptera) of the Guianas, pp. 1-306 in Insecta Mundi 732 (732) on page 93, DOI: 10.5281/zenodo.3678492
Sonnenfleckenzeichnung, unnummeriert.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.02.1968, erstellt von Peter Rovithis, Eugenides Planetarium in Athen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1968

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Eugenides Planetarium in Athen der Eugenides Stiftung, Griechenland. Instrument: Zeiss (Coudé-Refraktor 150mm, projiziertes Sonnenbild D = 25cm)