cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lettre de Jean-François Séguier à Non identifié Non identifié, 1784-05-21
Creators: name: Séguier, Jean-François
name: Jean-François Séguier
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Numismatique

description: [transcription] Mai 1784

Monsieur

On vient de me remettre votre lettre contenant la médaille d'Othon dont vous m'avez fait l'honneur de m'écrire dans votre lettre du 18 décembre dernier. à présent que j'ai sous mes yeux l'original, je vais renouveler tous mes soins pour tâcher de deviner la légende. Vous pensez trop favorablement de moi pour me croire capable de résoudre les difficultés qui se sont présentées à vos yeux. Demain matin je me mettrai à la besogne et dès que j'aurai bien médité, je vous la renverrai par la poste, comme vous me l'ordonnez.

Je suis avec respect et avec l'attachement le plus sincère,

Monsieur

Votre très humble et très obéissant serviteur

Séguier

Nîmes 21 mai 1784
description: Source: [lieu de Conservation] Reims, Archives municipales et communautaires [cote]carton XVIII
title: Development of asymmetric Tsuji-Trost allylation methodology: application towards the total synthesis of (+)-Zoapatanol
Creators: name: Skardon-Duncan, James
Publisher: name: University of Glasgow
Year: 2019
Subjects: subject: Zoapatanol, Tsuji-Trost allylation, asymmetric allylation, stereoselective allylation, cyclic ether, synthetic methodology, natural product, total synthesis.

description: This thesis describes the application of the asymmetric Tsuji-Trost allylation reaction to the functionalisation of medium-sized cyclic ethers. The aims of the work described within this thesis were to develop and optimise methodology for the palladium-catalysed stereoselective allylation of cyclic ether systems and then showcase this methodology in the total synthesis of the bioactive diterpenoid natural product (+)-zoapatanol. The first chapter provides a thorough literature review of the natural product (+)-zoapatanol, detailing its structure and origin, biological activity and previous efforts towards its synthesis. Following this, there is an extensive literature review of the key synthetic methodology utilised throughout this work, namely the Tsuji-Trost allylation reaction. The second chapter documents the synthesis of four medium-sized cyclic ether substrates and the results obtained from the application of the Tsuji-Trost allylation reaction to the stereoselective functionalisation of these systems. It was discovered that the reaction could be tuned to deliver the desired stereoisomer and that both the ring size and substitution at the position of allylation impacted the inherent substrate selectivity. Subsequently, the results obtained during studies towards the total synthesis of (+)-zoapatanol are presented. A robust route to the core structure of zoapatanol was established and the asymmetric Tsuji-Trost methodology was successfully applied during this route. The third chapter provides conclusions and potential future directions to build upon the work presented herein.
Extended amygdala Vipr2 neuronal circuitry characterization and excitatory chemogenetic modulation in alcohol drinking
Creators: name: Kandil, Isaac
name: Giardino, William
Publisher: name: Stanford Digital Repository
Year: 2025
Subjects: subject: Alcohol use disorder
subject: Extended amygdala
subject: Neural circuitry
subject: Chemogenetics
subject: Vasoactive intestinal peptide receptor 2
subject: Neurobiology

description: Substance use disorders are highly prevalent psychiatric conditions that have a high co-morbidity with anxiety disorders, but their precise neurobiological underpinnings are not fully understood. The bed nucleus of the stria terminalis (BNST) is a brain region within the extended amygdala network that is a major regulator of affective behavior and has been implicated in neural changes associated with drug-seeking behavior and pathological anxiety. With highly diverse neuromodulator and receptor expression, the functions of BNST neuronal subpopulations are thought to be highly dependent on their spatial locations, anatomical projections, and molecular identities. The oval nucleus of the BNST (ovBNST) has been widely studied for its role in anxiety-like behavior, but recent evidence points toward underappreciated heterogeneity in ovBNST function and molecular identity. For example, the ovBNST includes partially overlapping neuronal subgroups marked by Drd1, Sst, Pkcd, Ntsr1, and other components of behaviorally relevant neuromodulatory systems. An additional understudied ovBNST marker is the vasoactive intestinal peptide receptor 2 (Vipr2), and little is known about actions of endogenous Vipr2 ligands in the BNST, including the neuropeptides VIP and pituitary adenylyl cyclase activating polypeptide (PACAP). Immunohistochemical studies showed immunoreactivity of VIP-expressing axonal fibers densely innervating the mouse ovBNST. Anterograde viral tracing experiments in transgenic Vipr2-Cre mice revealed Vipr2-BNST outputs to brain areas relevant for affective behaviors, including subregions of the hypothalamus, thalamus, and midbrain. Chemogenetic neuromodulation during binge alcohol drinking experiments showed that activation of Vipr2-BNST neurons increased food intake and decreased ethanol preference. These results are the first to directly examine the connectivity and functionality of Vipr2 neurons in the BNST in binge alcohol drinking. Further studies will be needed to elucidate the possible roles of Vipr2-BNST neurons in other behaviors relevant to neuropsychiatric disorders.
Additional file 1 of Host starvation and in hospite degradation of algal symbionts shape the heat stress response of the Cassiopea-Symbiodiniaceae symbiosis
Creators: name: Toullec, Gaëlle
name: Rädecker, Nils
name: Pogoreutz, Claudia
name: Banc-Prandi, Guilhem
name: Escrig, Stéphane
name: Genoud, Christel
name: Olmos, Cristina Martin
name: Spangenberg, Jorge
name: Meibom, Anders
Publisher: name: figshare
Year: 2024
Subjects: subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Mental Health

description: Additional file 1: Figure S1. Schematic presentation of the experimental setup viewed from the side and from above with sampling design information. Figure S2. Photos of the medusae collected at SP2 on day 1 and 10 of the experiment in the control treatment, and heat stress treatment. Figure S3. Impact of heat stress on chlorophyll a content and algal symbiont density per wet weight. Figure S4. Temperature effects on the enrichment from assimilation of isotopically labeled bicarbonate and ammonium in the epidermis of heat-stressed medusae. Figure S5. SEM and 12C2- and 14N12C- NanoSIMS images corresponding to the correlative SEM and NanoSIMS images presented in Fig. 3. Figure S6. Tissue and cellular ultrastructure of control and heat-stressed medusae bells at SP2 imaged by light microscopy with H&E staining and SEM. Table S1. Number of NanoSIMS images per biological replicate and the associated number of regions of interest (ROIs) per Cassiopea compartment defined for the isotopic enrichment analyses.
THE INNOVATION IN BRAZILIAN ORGANIZATIONS: A STUDY ABOUT COMPETITIVENESS
Creators: name: SAMUEL STÁBILE
name: KARINA LEITE VIEIRA ANDRADE
name: JOÃO PAULO SANCHES DOS SANTOS
Publisher: name: figshare
Year: 2017
Subjects: subject: Law
subject: FOS: Law

description: The competitiveness of a company can be defined as its ability to act effectively in your business. Thus, investments in innovation are essential to the competitiveness of companies and, consequently, of countries. Innovation consists of applying changes to products, processes or business models that generate results. The objective of this study is to analyze the innovation practiced by Brazilian companies and their relationship with competitiveness. Through a bibliographic review it was verified that in Brazil, some companies are innovative to the point of supplying to the global market products with competitive characteristics in the international market. But most do not invest in innovation, using only some innovative practices already known globally.
Additional file 1 of Intersecting social determinants of health among patients with childcare needs: a cross-sectional analysis of social vulnerability
Creators: name: Ganguly, Anisha P.
name: Alvarez, Kristin S.
name: Mathew, Sheryl R.
name: Soni, Virali
name: Vadlamani, Suman
name: Balasubramanian, Bijal A.
name: Bhavan, Kavita P.
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Supplementary Material 1.
Characterization of Putative Lipid Binding Proteins in Enhygromyxa salina
Creators: name: Tiwari, Anushri
name: Dassama, Laura
Publisher: name: Stanford Digital Repository
Year: 2025
Subjects: subject: Bacterial sterol interactions
subject: Sterols
subject: Lipid-binding Proteins
subject: Antibiotics
subject: Antibiotic resistance
subject: Biochemistry

description: Bacteria interact with human-produced lipid sterols and lipids in a variety of ways that broadly impact human health. As such, identifying proteins involved in these interactions may inform new targets for therapeutic development. Historically, it has been difficult to identify proteins within bacterial genomes which may interact with lipid molecules. Large differences in structures and sequences of lipid-interacting proteins between eukaryotes and prokaryotes further complicates this task, so while eukaryotic interactions with cholesterol have been well studied, it is difficult to translate this prior work into bacteria. Recently, Enhygromyxa salina, a marine bacterium has been identified as a novel cholesterol producing bacterium. While E. salina is not biologically relevant to humans, E. salina may serve as a useful model system for understanding mechanisms by which biologically relevant bacteria interact with lipids. The overarching objective of this research is to utilize a novel tool to predict lipid binding proteins followed by biochemical and biophysical analyses to characterize lipid-interacting proteins in E. salina. In this study a YceI-like and DUF2071 domain containing protein were identified and characterized using these approaches. The results of this study begin to establish a workflow for identifying lipid interactomes within large bacteria genomes and provide initial results on the types of lipid molecules that may interact with these uncharacterized proteins.
Characterization of Neocortical Orexin/Hypocretin Receptor Expression in Dementias with Sleep Disturbances
Creators: name: Liu, Yu chen (Rellie)
name: Cobos, Inma
Publisher: name: Stanford Digital Repository
Year: 2025
Subjects: subject: Alzheimer's disease
subject: Sleep
subject: Neuropsychiatric symptoms
subject: Orexins
subject: Hypocretins
subject: Lewy body dementia
subject: Neuropathology
subject: Diffuse lewy body disease

description: Neuropsychiatric symptoms are extremely prevalent in Alzheimer’s disease (AD) and other dementias such as diffuse Lewy body disease (DLBD), yet the relationship between the manifestation of these symptoms and cognitive decline remains understudied. This thesis addresses the critical need for comprehensive research into the molecular basis of disturbances of the sleep-wake cycle, a common neuropsychiatric symptom that not only results in substantial clinical burden but has also been suggested to have an important bidirectional relationship with the progression of disease pathology. Previous research has revealed the importance of the orexin/hypocretin pathway in sleep regulation, primarily focusing on murine models and brainstem pathways. The neocortical substrate in human tissue remains, however, largely unexplored. In this project, I investigated the expression of orexin/hypocretin 2 receptors (HCRTR2) in relation to KIT-expressing interneurons, a subtype of neocortical interneurons that our lab has found to be dysregulated at early-stages of AD pathology. Using immunohistochemistry and in-situ hybridization methods, I assessed the expression profiles of both KIT and HCRTR2 in postmortem human brain tissue from cohorts of AD, DLBD, and healthy age-matched controls. I also confirmed that this particular interneuron subtype is also present in mice.  Interestingly, the results demonstrate a significant decrease in KIT and HCRTR2 mRNA expression levels as AD level pathology increases, but not in protein expression levels. This discrepancy between expression profiles can potentially be explained by the differential stabilities of proteins and RNAs or the decline in proteasome activity. More importantly, however, given that both disruptions in interneuron function and irregular sleep patterns may occur before cognitive symptoms manifest, the decline of cortical interneurons expressing mRNA signals encoding for the HCRTR2 protein could potentially contribute to the onset of sleep disturbances in AD and other forms of dementia. This project highlights the critical need for further investigations into the molecular mechanisms underlying sleep disturbances across different forms of dementia and draws a potential link between early interneuron dysregulation in AD and the development of dysregulated sleep circuits in the brain.
Additional file 1 of Incidental detection of Cladosporium in cytology
Creators: name: Santosh, Tummidi
name: Chakrabarti, Indranil
name: Palit, Aparna
name: Srivastava, Sonakshi
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Supplementary Material 1
Metric study of information literacy in Latin America: from bibliometrics to altmetrics
Creators: name: Tirado, Alejandro Uribe
name: Alhuay-Quispe, Joel
Publisher: name: figshare
Year: 2017
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: This study identifies the presence, productivity and influence of Ibero-American authors that write about information literacy (InfoLit). Using bibliometric and altmetric indicators, it seeks to analyze the impact and subsequent use of their scholarly works on social and scientific platforms. Fifty-five authors with the highest productivity were identified, based on the results of bibliometric studies on InfoLit carried out on both an international and Ibero-American scale in searches of major databases as well as publications collected in a Latin American wiki. Subsequently an analysis of bibliometric and altmetric indicators at the author and publication level was carried out, based on the results of searches on eight scientific platforms (Google Scholar, ResearchGate, Academia.edu, Mendeley, ORCID, IraLIS, E-LIS and EXIT), three social networks (Facebook, Twitter and LinkedIn), and data provided by a commercial supplier (Altmetric.com). Overall we found a greater presence of authors in ResearchGate (58%), Academia.edu (51%) and Google Scholar (49%) as opposed to Mendeley (25%) and ORCID (18%). Furthermore, as to social platforms, the greatest potential influence lies with Facebook, due to its high number of followers ( / top 10 authors). In addition, an analysis with the Spearman rho statistic, shows among some sources and platforms, a low correlation between the number of citations in Google Scholar and readings in Mendeley (r = 382) and low negative for mentions in blogs (r = 0,-237), Google+ (r = 0, -214) and Twitter (r = 0, -183). In conclusion, both the productivity and the impact-visibility center on specific authors writing about InfoLit, and various measurement resources show that for these authors there is a positive two-way impact from bibliometric to altmetric and vice versa.
WaterHCI-2022-Proceedings-with-DOI.pdf
Creators: name: Mann, Steve
name: Mattson, Mark
Publisher: name: figshare
Year: 2022
Subjects: subject: 120508 Urban Design
subject: FOS: Social and economic geography

description: ABSTRACT
WaterHCI (Water-Human-Computer Interaction)is a field of study and practice focusing on the design and creation of interactive devices, systems, and experiences at the intersection of water, humans, and technology. It is a relatively new field that originated in Ontario, Canada, in the 1960s, and was further developed at University of Toronto through a series of annual (de)conferences from 1998 to present.
This year, at our 24th annual WaterHCI (de)conference, we focus our attention on ideas for creating spaces and places (e.g. Ontario-Placemaking\tma) that combine fun and frolic with health and wellbeing, nature and spirituality, research and teaching, and innovation, where we can touch and be touched by water.
Trajectory optimization based on recursive B-spline approximation for automated longitudinal control of a battery electric vehicle
Creators: name: Jauch, Jens
Publisher: name: KIT Scientific Publishing
Year: 2024
Subjects: Trajektorienoptimierung
B-Spline
Approximation
Kalmanfilter
Fahrzeuglängsführung
trajectory optimization
B-spline
approximation
Kalman filter
vehicle longitudinal control

description: This work describes a method for weighted least squares approximation of an unbounded number of data points using a B-spline function. The method can shift the bounded B-spline function definition range during run-time. The approximation method is used for optimizing velocity trajectories for an electric vehicle with respect to travel time, comfort and energy consumption. The trajectory optimization method is extended to a driver assistance system for automated vehicle longitudinal control.
Warwick master thesis dissertation
Creators: name: Ford, Peter De
Publisher: name: figshare
Year: 2017
Subjects: subject: Statistics
subject: FOS: Mathematics
subject: Economics
subject: 140304 Panel Data Analysis
subject: FOS: Economics and business
subject: 80109 Pattern Recognition and Data Mining
subject: FOS: Computer and information sciences

description: We propose techniques to evaluate and optimise the performance of humanitarian organizations at a country scale using open online data. To evaluate performance, initially three data based indicators are proposed, which measure: how humanitarian organizations in a country supply aid proportionally to the demands; how able is an organization to reach the provinces more in need; and how well is aid being coordinated by regions of neighbouring provinces. Then, we propose other four indicators based mainly on network centrality measures, which are calculated from a network of partnerships between organizations, that for many countries can be inferred from a popular type of dataset. These four indicators measure: how big organizations are taking advantage of their size to make partnerships and influence others; how influential organizations tend to have partnerships among them and less with not so influential organizations; the role of international organizations as connectors between organizations; and the participation of organizations in doing partnerships. To optimise performance, we propose an algorithm that redistributes aid geographically in such a way that optimises some of the data and network based indicators proposed. The results were promising when we tested our ideas in the Afghanistan humanitarian scenario of 2015. We also compared some indicators calculated for Afghanistan with other seven countries, and there were good insights obtained.
Traits-related QTLs and genes and their potential applications in rice improvement under low phosphorus condition
Creators: name: Anumalla Mahender
name: Annamalai Anandan
name: Sharat Kumar Pradhan
name: Singh, Onkar Nath
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: The genetic improvement of rice over past decades has led to the loss of several genes which are responsible for nutrient acquisition and soil-related stresses. Phosphorus (P) is a non-renewable resource and inevitable element of metabolic functions in plants. By pedogenesis process, organic matter contributes to renewing soil P in lesser extent. Therefore, improvement of the P use efficiency is one of the most imperative traits in rice breeding program, which is governed by quantitative trait loci (QTLs). QTLs controlling low P associated morphological and physiological traits in rice were investigated mostly during last one and half decade by using diverse mapping populations. Comprehensive and meticulous survey from literature, we found that to date 133 P associated QTLs of morpho-physiological traits were reported to be distributed on twelve chromosomes and majority of these QTLs localized on chromosome 1, 2 and 12. For the first time, a complete figure is presented in this review on chromosome wise with respective QTLs associated with low P for easy understanding and selecting markers for future prospect. Further, it is necessary to understand the molecular mechanisms and regulation of genes and traits associated with low P to develop tolerant rice cultivars using functional marker-assisted selection.
title: ADCO, Cart. 186 (11 H 71), f. 0182v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la Côte-d'Or, C
art. 186 (11 H 71). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la
 Côte-d'Or, Cart. 186 (11 H 71), f. 0182v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-
project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Lipase-catalysed two-step desymmetrization of 2-methylmalonic dipyrazolide for preparation of optically pure enantiomer in organic solvents
Creators: name: Ching-Hsiang Hsu
name: Shau-Wei Tsai
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: A lipase-catalysed two-step butanolytic desymmetrization process for the preparation of pyrazolidyl butyl (S)-2-methylmalonate from 2-methylmalonic dipyrazolide was developed. The best reaction condition of using lipase PS-D in anhydrous n-hexane at 55 °C was first selected, leading to high yield and enantiomeric excess for the remained (S)-enantiomer. The kinetic analysis by considering the competitive inhibition from butanol was then carried out for obtaining the stereoselectivity of E1 = 11.2 for the first desymmetrization and enantiomeric ratio of E3E2−1=11.8 for the subsequent kinetic resolution. The thermodynamic analysis furthermore revealed that the enzyme stereodiscrimination was enthalpy-driven for the desymmetrization step, but changed as entropy-driven for the kinetic resolution step.
Engineering Nanocellulose: Chemical Functionalization for Applications
Creators: name: MENDOZA, DAVID JORAM
Publisher: name: Monash University
Year: 2022
Subjects: subject: 91209 Polymers and Plastics
subject: FOS: Materials engineering
subject: Organic Chemistry
subject: FOS: Chemical sciences
subject: 100708 Nanomaterials
subject: FOS: Nanotechnology

description: Nanocellulose is an exciting, green and abundant bio-based material due to its desirable properties and tunable surface chemistry. It can be made functional and of higher value by engineering its surface. In this thesis, three novel chemical modification routes for nanocellulose were developed: TEMPO-periodate oxidation, click-type copper-catalyzed cycloaddition reaction and graft polymerization. These chemical modifications introduced different functional groups and molecules which allowed the preparation of materials such as highly-transparent gels, anti-UV materials and thermoresponsive biomaterials. These properties can assist these materials in being used in important applications in different fields including biomedical, diagnostics, cosmetics, and packaging.
title: ADCO, Cart. 186 (11 H 71), f. 0353v
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la Côte-d'Or, C
art. 186 (11 H 71). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, t. II (XVe siècle), tome II, Archives départementales de la
 Côte-d'Or, Cart. 186 (11 H 71), f. 0353v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-
project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Time-Efficient Analysis of Complex Dependencies
Creators: name: Vollmer, Michael
Publisher: name: Karlsruhe
Year: 2020

description: The volumes of data that are collected and analyzed in all aspects of life rise steadily and offer numerous challenges and opportunities. When analyzing large volumes of data, two main considerations are the capability to detect relationships within the data and the time efficiency necessary when processing the data. Large data sets in particular often contain dependencies that are less obvious than linear or proportional relationships. Such complex dependencies could be quantified and analyzed with methods from the field of information theory. In this dissertation, we study time-efficient methods to detect, quantify and illustrate complex dependencies.
Additional file 1 of Progression analysis versus traditional methods to quantify slowing of disease progression in Alzheimer’s disease
Creators: name: Jönsson, Linus
name: Ivkovic, Milana
name: Atri, Alireza
name: Handels, Ron
name: Gustavsson, Anders
name: Hahn-Pedersen, Julie Hviid
name: León, Teresa
name: Lilja, Mathias
name: Gundgaard, Jens
name: Raket, Lars Lau
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Additional file 1. Simulation of treatment effects. Single simulation – Cox proportional hazards model. Comparison of statistical power.
Cuidemos a las rayas
Creators: name: Ramirez-Valdez, Arturo
name: García-Hernández, Jaqueline
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310301
subject: Behavioural ecology
classificationCode: 310307
subject: Population ecology
classificationCode: 310305
subject: Marine and estuarine ecology (incl. marine ichthyology)
classificationCode: 310914
subject: Vertebrate biology
classificationCode: 370801
subject: Biological oceanography

description: Recientemente causó polémica la noticia sobre la mutilación de aguijón que sufrieron mantas en las playas de Huatabampo, Sonora. Desde todos los escenarios esta es una estrategia incorrecta, ya que dicha acción representa un perjuicio a la fauna silvestre, un acto que atenta contra la posibilidad de sobrevivencia de los individuos, ilegal en el marco de regulaciones mexicanas y completamente ineficaz como forma de control de afectaciones a turistas. La simple manipulación representa estrés a los organismos y nadie que no tenga permisos correspondientes debería manipular fauna silvestre. Asimismo, la liberación de organismos arrojándolos en la superficie los deja expuestos a depredación en el retorno a su hábitat. Respecto a la mutilación del aguijón, este corte deja vulnerables a los individuos y sin capacidad de una respuesta de defensa, debido a que el aguijón vuelve a crecer en un lapso de uno a tres años.
Additional file 1 of Deep learning segmentation of the choroid plexus from structural magnetic resonance imaging (MRI): validation and normative ranges across the adult lifespan
Creators: name: Eisma, Jarrod J.
name: McKnight, Colin D.
name: Hett, Kilian
name: Elenberger, Jason
name: Han, Caleb J.
name: Song, Alexander K.
name: Considine, Ciaran
name: Claassen, Daniel O.
name: Donahue, Manus J.
Publisher: name: figshare
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: Biological Sciences not elsewhere classified

description: Additional file 1. Additional figures and tables.
Termination of obligations: theoretical aspects
Creators: name: Kostruba, Anatoliy
Publisher: name: Zenodo
Year: 2017
Subjects: civi law
legal fact
legal relations
law of contract
obligations

description: Монографія присвячена дослідженню договірного регулювання приватноправових відносин на основі аналізу засадничих теоретичних положень приватноправової теорії крізь призму особливих умов євроінтеграційних процесів в Україні. Подано аналіз феномену договору в приватноправових відносинах. Особливу увагу приділено новітнім змінам договірного регулювання. Охарактеризовано особливості договірного режиму в різних сферах приватноправових відносин. Сформульовано низку пропозицій щодо удосконалення чинного законодавства та практики його застосування. Книга адресована науковим та науково-педагогічним працівникам вищих навчальних закладів і наукових установ, студентам, аспірантам, докторантам, суддям, адвокатам, нотаріусам та всім, хто цікавиться актуальними питаннями договірного регулювання приватноправових відносин в Україні.
title: ADCO, Cartulaire de Fontenay, premier fragment (XIIIe siècle), Cart. 201 (15 H 9), 175 folios, f. 075v
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2009
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Fontenay, premier fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), 175 folios. Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Fontenay, premier fragment (XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 201 (15 H 9), 175 folios, f. 075v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb119679755
description: Provenance: https://www.geonames.org/7874015
description: Provenance: http://www.idref.fr/027691802/id
description: Provenance: abbaye de Fontenay
description: Provenance: http://www.wikidata.org/entity/Q464918
title: 02_1151
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Figure S3 from Identifying the most surprising victims of mass extinction events: an example using Late Ordovician Brachiopods
Creators: name: Finnegan, Seth
name: Rasmussen, Christian M. Ø.
name: Harper, David A. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Crossplots of median predicted risk estimates from models based on the full dataset and from models based on the dataset with single-interval and single-region genera removed. Median predicted risk estimates are based on all background intervals for the full dataset but exclude interval S1 (due to edge effects, see figure S2 caption) for the culled dataset. Both sets of risk estimates are strongly correlated for both the latest Katian (Katian4) interval and the Hirnantian interval (Katian 4 R2 = 0.76, Hirnantian, R2 = 0.76).
Figure S4 from Identifying the most surprising victims of mass extinction events: an example using Late Ordovician Brachiopods
Creators: name: Finnegan, Seth
name: Rasmussen, Christian M. Ø.
name: Harper, David A. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Same as Figure 2 but with single-interval and single-region genera removed from both the background and mass extinction intervals. Latest Katian (A) and late Hirnantian (B) genera ranked by their median predicted extinction risk based on the four background interval models that can be analyzed after exclusion of single-interval genera (S2, K1, K2, and K3). Bars indicate full range of risk predictions from background models. Genera that survived are indicated by blue, those that went extinct are indicated by red. Enlarge figure in online version to read genus names. Labels indicate core members of the deep-water “Foliomena fauna”.
Additional file 1 of Radiomics-based discrimination of coronary chronic total occlusion and subtotal occlusion on coronary computed tomography angiography
Creators: name: Li, Jun
name: Ren, Lichen
name: Guo, Hehe
name: Yang, Haibo
name: Cui, Jingjing
name: Zhang, Yonggao
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified

description: Supplementary Material 1
An Equilibrium Analysis of the Effects of Neighborhood-based Interventions on Children
Creators: name: Chyn, Eric
name: Daruich, Diego
Publisher: name: Stanford Digital Repository
Year: 2022
Subjects: neighborhood effects
housing vouchers
intergenerational mobility

description: To study the effects of neighborhood and place-based interventions, this paper incorporates neighborhood effects into a general equilibrium (GE) heterogeneous-agent overlapping-generations model with endogenous location choice and child skill development. Importantly, housing costs, as well as neighborhood effects, are endogenously determined in equilibrium. Having calibrated the model using U.S. data, we use simulations to show that predictions from the model match reduced form evidence from experimental and quasi-experimental studies of housing mobility and urban development programs. After this validation exercise, we study the long-run and large-scale impacts of vouchers and place-based subsidies. Both policies result in welfare gains by reducing inequality and generating improvements in average skills and productivity, all of which offset higher levels of taxes and other GE effects. We find that a voucher program generates larger long-run welfare gains relative to place-based policies. Our analysis of transition dynamics, however, suggests there may be more political support for place-based policies.
Figure S2 from Identifying the most surprising victims of mass extinction events: an example using Late Ordovician Brachiopods
Creators: name: Finnegan, Seth
name: Rasmussen, Christian M. Ø.
name: Harper, David A. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Summary of multiple logistic regression models based on dataset with single-region and single-interval genera removed. Each column represents an interval and each row a predictor. Colours indicate sign of log-odds associated with the predictor in a given interval and text gives the log-odds. Positive log-odds (magenta) indicate that as the predictor value increases marginal extinction risk increases; negative log-odds (green) indicate that as the predictor value increases marginal extinction risk decreases. Only predictors that are significant at the 95% confidence level are plotted. S2: Sandbian 2, K1: Katian 1, K2: Katian 2, K3: Katian 3 ,K4: Katian 4, H: Hirnantian. Because Sandbian 1 is the first interval in our database all genera that last appear in this interval are by definition of single-interval genera; hence Sandbian 1 is not included in selectivity analyses of the culled dataset.
Lettre de Jean-François Séguier à Esprit-Claude-François Calvet, 1777-12-01
Creators: name: Séguier, Jean-François
name: Jean-François Séguier
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: [transcription] Je vous rends bien des grâces, mon cher monsieur, du soin que vous avez pris pour l’envoi de mon manuscrit qui m’a été rendu très exactement avant-hier. J’en écris à M. de Saint-Véran pour l’informer de son arrivée et je lui marque que vous avez eu la bonté de me le faire passer. Je vous suis infiniment redevable de tout ce que vous avez fait afin qu’il ne s’égara point en route. J’avais écrit il y a quelques jours au père Topin doctrinaire et devant provincial, qui devait venir ici incessamment de passer chez vous pour le prendre, mais comme il a trop différé de se rendre ici, vous avez été plus diligent.

Conservez-moi votre chère amitié et croyez-moi inviolablement,

Mon cher ami, votre très humble serviteur, Séguier.

à Nismes, le 1er décembre 1777.
description: [personnes citées] Joseph Antoine Topin, Joseph-Dominique Fabre de Saint-Véran
description: Source: [lieu de Conservation] Avignon, Médiathèque Ceccano [cote]ms. 2364, fol. 288
Figure S5 from Identifying the most surprising victims of mass extinction events: an example using Late Ordovician Brachiopods
Creators: name: Finnegan, Seth
name: Rasmussen, Christian M. Ø.
name: Harper, David A. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Same as Figure S1 but with single-interval and single-region genera removed from both the background and mass extinction intervals. Histograms showing frequency distributions of simulated Foliomena fauna genus extinctions for each background interval model. In each sampling iteration, 112 genera were randomly drawn using per-genus expected risk estimates from the associated background model as sampling probabilities. 10,000 iterations were performed for each model. Red arrows indicate the number of Foliomena fauna extinctions observed during the latest Katian.
Supplemental Figures and Tables from Persistent and plastic effects of temperature on DNA methylation across the genome of threespine stickleback (Gasterosteus aculeatus)
Creators: name: Metzger, David C. H.
name: Schulte, Patricia M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 60408 Genomics

description: Tables S1, 2,3, and 5, and Figures S1 and S2
AlphaPortfolio: Direct Construction through Deep Reinforcement Learning and Interpretable AI 
Creators: name: Cong, Lin William
name: Tang, Ke
name: Wang, Jingyuan
name: Zhang, Yang
Publisher: name: Stanford Digital Repository
Year: 2022
Subjects: artificial intelligence
asset pricing
explainable AI
machine learning,
portfolio theory,
batched/offline reinforcement learning.

description: We directly optimize the objectives of portfolio management via reinforcement learning—an alternative to conventional supervised-learning-based paradigms that entail first-step estimations of return distributions, pricing kernels, or risk premia. Building upon breakthroughs in AI, we develop multi-sequence neural-network models tailored to the distinguishing features of financial data, while allowing training without labels and potential market interactions. Our AlphaPortfolio yields stellar out-of-sample performances (e.g., Sharpe ratio above two and over 13% risk-adjusted alpha with monthly re-balancing) that are robust under various economic restrictions and market conditions (e.g., exclusion of small stocks and short-selling). Moreover, we project AlphaPortfolio onto simpler modeling spaces (e.g., using polynomial-feature-sensitivity) to uncover key drivers of investment performance, including their rotation and nonlinearity. More generally, we highlight the utility of deep reinforcement learning in finance and “economic distillation” for model interpretation.
title: Paratexte_Les Petits arts d'amateur
Creators: name: AmateurS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Paratexte
description: ID_PARA_00870
Figure S1 from Identifying the most surprising victims of mass extinction events: an example using Late Ordovician Brachiopods
Creators: name: Finnegan, Seth
name: Rasmussen, Christian M. Ø.
name: Harper, David A. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Histograms showing frequency distributions of simulated Foliomena fauna genus extinctions for each background interval model. In each sampling iteration, 112 genera were randomly drawn using per-genus expected risk estimates from the associated background model as sampling probabilities. 10,000 iterations were performed for each model. Red arrows indicate the number of Foliomena fauna extinctions observed during the latest Katian.
Additional file 1 of Prevalence, correlates, and reasons for substance use among adolescents aged 10–17 in Ghana: a cross-sectional convergent parallel mixed-method study
Creators: name: Kyei-Gyamfi, Sylvester
name: Kyei-Arthur, Frank
name: Alhassan, Nurudeen
name: Agyekum, Martin Wiredu
name: Abrah, Prince Boamah
name: Kugbey, Nuworza
Publisher: name: figshare
Year: 2024
Subjects: subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Mental Health
subject: Computational Biology

description: Working status of adolescents by sex.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 205
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 205, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 205, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Description of potential extinction risk predictors from Identifying the most surprising victims of mass extinction events: an example using Late Ordovician Brachiopods
Creators: name: Finnegan, Seth
name: Rasmussen, Christian M. Ø.
name: Harper, David A. T.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Description of the various aspects of geographic, bathymetric, environmental, and stratigraphic distribution considered as potential predictors of apparent extinction risk.