cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Small intestine hexose transport in experimental diabetes: Increased transporter mRNA and protein expression in enterocytes
Creators: name: Chen, J.
name: Flink, S.
name: Chang, E.B.
name: Burant, C.F.
name: DePaoli, A.M.
name: Buse, J.B.
name: Lee, W.-S.
name: Hediger, M.A.
Publisher: name: The American Society for Clinical Investigation
Year: 1994

description: The effect of insulinopenic diabetes on the expression of glucose transporters in the small intestine was investigated. Enterocytes were sequentially isolated from jejunum and ileum of normal fed rats, streptozotocin-diabetic rats, and diabetic rats treated with insulin. Facilitative glucose transporter (GLUT) 2, GLUT5, and sodium-dependent glucose transporter 1 protein content was increased from 1.5- to 6-fold in enterocytes isolated from diabetic animals in both jejunum and ileum. Insulin was able to reverse the increase in transporter protein expression seen after induction of diabetes. There was a four- to eightfold increase in the amount of enterocyte glucose transporter mRNA after diabetes with greater changes in sodium-dependent glucose transporter 1 and GLUT2 than in GLUT5 levels. In situ hybridization showed that after the induction of diabetes there was new hybridization in lower villus and crypt enterocytes that was reversed by insulin treatment. Thus, the increase in total hexose transport caused by diabetes is due to a premature expression of hexose transporters by enterocytes along the crypt-villus axis, causing a cumulative increase in enterocyte transporter protein during maturation. These changes are likely to represent an adaptive response by the organism to increase nutrient absorption in a perceived state of tissue starvation. These adaptive changes may lead to exacerbation of hyperglycemia in uncontrolled diabetes.
Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice
Creators: name: Moye-Rowley, W.S.
name: Pessin, J.E.
name: Olson, A.L.
name: Liu, M.-L.
name: Bell, G.I.
name: Buse, J.B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1993

description: To examine the hormonal/metabolic as well as tissue-specific expression of the GLUT4/muscle-fat facilitative glucose transporter gene, we have generated several transgenic mouse lines expressing a human GLUT4 mini-gene which extends 5.3 kilobases (kb) upstream of transcription start and terminates within exon 10. This construct (hGLUT4-11.5) was expressed in a tissue- specific pattern identical to the endogenous mouse GLUT4 gene. The transcription initiation sites of the transgenic construct were similar to the GLUT4 gene expressed in human tissues. To investigate the hormonal/metabolic-dependent regulation of GLUT4, the transgenic animals were made insulin-deficient by streptozotocin (STZ) treatment. In these animals, STZ-induced diabetes resulted in a parallel decrease in endogenous mouse GLUT4 mRNA and the transgenic human GLUT4 mRNA in white adipose tissue, brown adipose tissue, and cardiac muscle. Similarly, insulin treatment of the STZ- diabetic animals restored both the endogenous mouse and transgenic human GLUT4 mRNA levels. To further define cis-regulatory regions responsible for this hormonal/metabolic regulation, the same analysis was performed on transgenic animals which carry 2.4 kb of the human GLUT4 5'-flanking region fused to a CAT reporter gene (hGLUT4[2.4]-CAT). This reporter construct responded similarly to the human GLUT4 mini-gene demonstrating that the element(s) controlling hormonal/metabolic regulation and tissue specificity all reside exclusively within 2.4 kb of the transcriptional initiation site.
title: Infrapopliteal occlusive arterial disease : Imaging evaluation.
Creators: name: Jose, Anstin
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Arteriosclerosis
subject: Contrast agent-intravenous
subject: MR-Angiography
subject: CT-Angiography
subject: Catheter arteriography
subject: Vascular
subject: Interventional vascular
subject: Arteries / Aorta

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: To compare the diagnostic accuracy of various investigation modalities in imaging of infrapopliteal occlusive arterial disease. Assess the correlation of various non invasive imaging investigations with conventional catheter angiography in infra...
Surface code architecture for donors and dots in silicon with imprecise and nonuniform qubit couplings
Creators: name: Pica, G.
name: Lovett, B. W.
name: Bhatt, R. N.
name: Schenkel, T.
name: Lyon, S. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: A scaled quantum computer with donor spins in silicon would benefit from a viable semiconductor framework and a strong inherent decoupling of the qubits from the noisy environment. Coupling neighbouring spins via the natural exchange interaction according to current designs requires gate control structures with extremely small length scales. We present a silicon architecture where bismuth donors with long coherence times are coupled to electrons that can shuttle between adjacent quantum dots, thus relaxing the pitch requirements and allowing space between donors for classical control devices. An adiabatic SWAP operation within each donor/dot pair solves the scalability issues intrinsic to exchange-based two-qubit gates, as it does not rely on sub-nanometer precision in donor placement and is robust against noise in the control fields. We use this SWAP together with well established global microwave Rabi pulses and parallel electron shuttling to construct a surface code that needs minimal, feasible local control.
description: Published version - more detailed discussions, robustness to dephasing pointed out additionally
Memorabilidade como principal construto do consumo da experiência: reflexões teóricas
Creators: name: Gomes, Marizagela
Publisher: name: Zenodo
Year: 2022
Subjects: Consumo da experiência
Economia da experiência
Memorabilidade

description: Novos processos de consumo estão adentrando a sociedade contemporânea. Destaca-se o consumo da experiência uma forma de recepção em que o consumidor não adquire apenas um produto ou serviço, mas a história, experiência e sentimento que podem ser agregados ao produto. O conceito de consumo de experiência pode ser exatamente a partir da consideração à memorabilidade de experiências de consumo que se refere à indução consistente de lembranças vivas e perenes de elementos das passadas passadas travadas pelos consumidores com as propriedades dos produtos e serviços consumidos. Diante disso, o presente artigo apresenta extensa revisão bibliográfica que possibilita um resgate das origens e sistematizar o conhecimento produzido sobre economia da experiência, consumo da experiência e construção da memorabilidade. Por meio de uma abordagem exploratória e teórica, são mantidas questões importantes relacionadas ao assunto consumo da experiência assim como o construto memorabilidade apontado como variável em pesquisas empíricas. Desse modo, este artigo teórico contribui para a compreensão do tema em estudo na medida em que acrescenta a perspectiva do consumo da experiência em sua evolução conceitual e seu principal construto memorabilidade na visão das teorias cognitivistas e teorias da análise do comportamento (Skinner, 1953; Baum, 2003).
description: Ensaio teórico
title: Association of hyperdense middle cerebral artery sign with recanalization rates in patients with acute ischemic stroke
Creators: name: Ortiz Andrade, Cesar Augusto
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Ischaemia / Infarction
subject: Image verification
subject: Embolism / Thrombosis
subject: Stents
subject: Removal
subject: Recanalisation
subject: CT
subject: Catheter arteriography
subject: Neuroradiology brain
subject: Interventional vascular
subject: Emergency

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Introduction The hyperdense middle cerebral artery sign (HMCAS) was first described in 1983 as a high-density structure within the territory of the middle cerebral artery (MCA) at non-enhanced computed tomography (NECT) scans of patients with acute...
Article Review: The 18th Century Aesthetics and Their Associations withLandscape Architecture and Environmental Art
Creators: name: Pattamon Selanon
Publisher: name: Thammasat University
Year: 2019
Subjects: Aesthetics
the Beautiful
the Sublime
the Picturesque
Landscape Architecture
Environmental Art

description: Journal of Architectural/Planning Research and Studies, 16, 1, 1-14
Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice
Creators: name: Pessin, J.E.
name: Olson, A.L.
name: Moye-Rowley, W.S.
name: Bell, G.I.
name: Liu, M.-L.
name: Buse, J.B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1992

description: To study the molecular basis of tissue-specific expression of the GLUT4/muscle-fat facilitative glucose transporter gene, we generated lines of transgenic mice carrying 2.4 kilobases of the 5'-flanking region of the human GLUT4 gene fused to a chloramphenicol acetyltransferase (CAT) reporter gene (hGLUT4[2.4]-CAT). This reporter gene construct was specifically expressed in tissues that normally express GLUT4 mRNA, which include both brown and white adipose tissues as well as cardiac, skeletal, and smooth muscle. In contrast, CAT reporter activity was not detected in brain or liver, two tissues that do not express the GLUT4 gene. In addition, the relative levels of CAT mRNA driven by the human GLUT4 promoter in various tissues of these transgenic animals mirrored those of the endogenous mouse GLUT4 mRNA. Since previous studies have observed alterations in GLUT4 mRNA levels induced by fasting and refeeding (Sivitz, W. I., DeSautel, S. L., Kayano, T., Bell, G. I., and Pessin, J. E. (1989) Nature 340, 72-74), the regulated expression the hGLUT4[2.4]-CAT transgene was also assessed in these animals. Fasting was observed to decrease CAT activity in white adipose tissue which was super- induced upon refeeding. These alterations in CAT expression occurred in parallel to the changes in endogenous mouse GLUT4 mRNA levels. Although CAT expression in skeletal muscle and brown adipose tissue was unaffected, the endogenous mouse GLUT4 mRNA was also refractory to the effects of fasting/refeeding in these tissues. These data demonstrate that 2.4 kilobases of the 5'-flanking region of the human GLUT4 gene contain all the necessary sequence elements to confer tissue-specific expression and at least some of the sequence elements controlling the hormonal/metabolic regulation of this gene.
title: Organising pneumonia: atypical imaging findings in a mixed cohort of patients, including those with an underlying malignancy
Creators: name: Patel, Nikhil
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Inflammation
subject: Cancer
subject: Diagnostic procedure
subject: PET-CT
subject: CT-High Resolution
subject: CT
subject: Thorax
subject: Respiratory system
subject: Lung

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate the atypical presentations of organising pneumonia encountered in patients with and without concomitant...
title: Hydronephrosis in the adult – uncommon non-lithiasic causes
Creators: name: Mota Louro, João
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Obstruction / Occlusion
subject: Dilatation
subject: Diagnostic procedure
subject: Ultrasound
subject: CT
subject: Conventional radiography
subject: Urinary Tract / Bladder
subject: Kidney
subject: Anatomy

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review the anatomy of the urinary collecting system. To review the common imaging findings of hydronephrosis in its acute and chronic setting. To illustrate uncommon non-lithiasic causes of hydronephrosis in multimodality imaging...
Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus
Creators: name: Kusari, J.
name: Henry, R.R.
name: Olefsky, J.M.
name: Buse, J.B.
name: Verma, U.S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1991

description: Insulin resistance is a common feature of non-insulin-dependent diabetes mellitus (NIDDM) and ''diabetes susceptibility genes'' may be involved in this abnormality. Two potential candidate genes are the insulin receptor (IR) and the insulin-sensitive glucose transporter (GLUT-4). To elucidate whether structural defects in the IR and/or GLUT-4 could be a primary cause of insulin resistance in NIDDM, we have sequenced the entire coding region of the GLUT-4 gene from DNA of six NIDDM patients. Since binding properties of the IRs from NIDDM subjects are normal, we also analyzed the sequence of exons 16-22 (encoding the entire cytoplasmic domain of the IR) of the IR gene from the same six patients. When compared with the normal IR sequence, no difference was found in the predicted amino acid sequence of the IR cytoplasmic domain derived from the NIDDM patients. Sequence analysis of the GLUT-4 gene revealed that one patient was heterozygous for a mutation in which isoleucine (ATC) was substituted for valine (GTC) at position 383. Consequently, the GLUT-4 sequence at position 383 was determined in 24 additional NIDDM patients and 30 nondiabetic controls and all showed only the normal sequence. From these studies, we conclude that the insulin resistance seen in the great majority of subjects with the common form of NIDDM is not due to genetic variation in the coding sequence of the IR β subunit, nor to any single mutation in the GLUT-4 gene. Possibly, a subpopulation of NIDDM patients exists displaying variation in the GLUT-4 gene.
(101293) Charles Latcham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
บทบาทพื้นที่สาธารณะในการพัฒนามหาวิทยาลัยธรรมศาสตร์ ศูนย์รังสิตพ.ศ. 2577
Creators: name: พรทิพย์ กิ้มนวน
Publisher: name: Thammasat University
Year: 2019
Subjects: พื้นที่สาธารณะ
บทบาทพื้นที่สาธารณะ
ผังแม่บท
มหาวิทยาลัยธรรมศาสตร์ศูนย์รังสิต

description: Journal of Architectural/Planning Research and Studies, 16, 1, 15-34
แนวทางการลงทุนปรับปรุงเปลือกอาคารบ้านประหยัดพลังงานตามเกณฑ์ประเมินพลังงาน TEEAM
Creators: name: จารุวรรณ สุขสีดา
Publisher: name: Thammasat University
Year: 2019
Subjects: ระยะเวลาคืนทุน
การประเมินอาคารเพื่อการประหยัดพลังงานและเป็นมิตรต่อสภาพแวดล้อม
ประหยัดพลังงาน
เปลือกอาคาร
การปรับปรุงบ้าน

description: Journal of Architectural/Planning Research and Studies, 16, 1, 69-82
title: Developing a Comprehensive Scoring System for Screening Soft Tissue Sarcomas by Ultrasound
Creators: name: Wali, Luqman
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Tissue characterisation
subject: Screening
subject: Audit and standards
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Soft tissues / Skin
subject: Musculoskeletal system

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Soft tissue sarcomas are rare cancers accounting for approximately less than 1% of all adult cancers, occurring more frequently in younger adults 1 . Although relatively uncommon, they are known to be deadly due to delayed diagnosis or metastasis at...
title: Blind eyes: ocular trauma
Creators: name: Mc Callum, Jason
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Eyes
subject: Emergency
subject: Head and neck
subject: CT
subject: Education
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To illustrate computer tomography (CT) findings when facing a patient with orbital traumatism without bone fracture association. To consider the importance in the trajectory and strength a given foreign body has regarding its potential...
title: A pictorial review of gastrointestinal stromal tumors (GISTs): radiologic findings with pathologic correlation
Creators: name: Baraças, Catarina
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Pathology
subject: Neoplasia
subject: Surgery
subject: Staging
subject: Biopsy
subject: Ultrasound
subject: MR
subject: CT
subject: Gastrointestinal tract
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The authors' aim is to present a pictorial review of gastrointestinal stromal tumors (GISTs). For that purpose, they illustrate the radiological features of GISTs along with the pathological...
Major histocompatibility complex restriction fragment length polymorphisms define three diabetogenic haplotypes in bb and bbn rats
Creators: name: Lees, S.
name: Milford, E.M.
name: Eisenbarth, G.S.
name: Chaplin, D.
name: Rifai-Haddad, R.
name: Taniguchi, H.
name: Buse, J.B.
name: Seidman, J.G.
name: Jackson, R.A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1985

description: BB rats spontaneously develop insulin-dependent, ketosis-prone diabetes mellitus (DM)) Their disease is of autoimmune etiology, since it is characterized by: (a) lymphocytic and rnacrophage inflammation of pancreatic islets (1), (b) circulating autoantibodies that bind to pancreatic islets of Langerhans (2), (c) increased incidence of Ia antigen-bearing T lymphocytes associated with the development of diabetes (3), (d) progressive and selective destruction of insulin-producing beta ceils (1, 4), (e) the ability to transfer disease to immunodeficient animals with concanavalin A-activated splenic lymphocytes (5), and (f) selective destruction of beta cells in transplanted islets (6); in addition, it can be prevented with many forms of immunotherapy (7). BB rats also exhibit a profound T cell lymphocytopenia with an almost total lack of circulating T lymphocytes, although their thymocytes are normal in number and cell surface phenotype (8). In breeding studies, we and others (9, 10) have shown that at least two genes contribute to the development of diabetes in the BB rat. One is autosomal recessive and determines the profound T cell immunodeficiency present in affected rats at birth. The second is linked to RTI, the rat major histocompatibility complex (MHC).
Water on hexagonal boron nitride from diffusion Monte Carlo
Creators: name: Al-Hamdani, Yasmine S.
name: Ma, Ming
name: Alfè, Dario
name: von Lilienfeld, O. Anatole
name: Michaelides, Angelos
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Despite a recent flurry of experimental and simulation studies, an accurate estimate of the interaction strength of water molecules with hexagonal boron nitride is lacking. Here we report quantum Monte Carlo results for the adsorption of a water monomer on a periodic hexagonal boron nitride sheet, which yield a water monomer interaction energy of -84 +/- 5 meV. We use the results to evaluate the performance of several widely used density functional theory (DFT) exchange correlation functionals, and find that they all deviate substantially. Differences in interaction energies between different adsorption sites are however better reproduced by DFT.
การคาดการณ์ผลกระทบของเรขาคณิตของเมืองต่อปรากฏการณ์เกาะความร้อนเมือง: กรณีศึกษากรุงเทพมหานคร
Creators: name: ประรินทร์ บุตรดี
Publisher: name: Thammasat University
Year: 2019
Subjects: ปรากฏการณ์เกาะความร้อนเมือง
เรขาคณิตของเมือง
หุบเขาถนนของเมือง
อัตราส่วนความสูงต่อความกว้าง
อุณหภูมิอากาศ
ความเข้มข้นของเกาะความร้อนเมือง

description: Journal of Architectural/Planning Research and Studies, 16, 1, 107-124
Two genes required for diabetes in BB rats: Evidence from cyclical intercrosses and backcrosses
Creators: name: Milford, E.L.
name: Michael Williams, R.
name: Carpenter, C.B.
name: Rifai, R.
name: Eisenbarth, G.S.
name: Jackson, R.A.
name: Buse, J.B.
name: Pelletier, D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1984

description: The BB rat strain spontanteously develops diabetes mellitus which rapidly progresses to ketoacidosis and death if not treated with exogenous insulin. 40-60% of BB rats develop overt diabetes and exhibit prominent insulitis, selective pancreatic beta cell destruction, and circulating antibodies to islet cell surfaces. Diabetes can be prevented with multiple forms of immunotherapy and can be transferred with activated splenic iymphocytes. In addition to the diabetic syndrome, BB rats have a striking lymphophenia characterized by an almost total lack of circulating T cells. Colle et al., using a sequential breeding program, have described associations between the development of diabetes and the inheritance of major histocompatibility complex (MHC) 1 genes, lymphopenia, and susceptibility to pancreatic lymphocytic infiltrates.
Kallikrein-induced uterine contraction independent of kinin formation
Creators: name: Buse, J.
name: Shimamoto, K.
name: Margolius, H.S.
name: Chao, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1981

description: Responses of smooth muscle to kallikreins (EC 3.4.21.8) are generally considered to result from kinin formation. This premise was reexamined with the isolated rat uterus. Rat urinary kallikrein or bradykinin produced dose-dependent contractions of rat uterus but kallikrein was 5-fold more potent than bradykinin. Kallikrein caused an immediate series of rhythmic contractions which could be increased gradually with subsequent addition of kininogen substrate. Kallikrein-induced contractions were unaffected by carboxypeptidase B or a bradykinin antiserum whereas bradykinin-induced contractions were attenuated or abolished. Other serine proteinases, including trypsin, either did not induce contraction in the absence of added kininogen or did so minimally. Although small amounts of kininogen-like substrate were found in uterine tissue, detectable kinin levels (greater than 4 pg) could not be found in bathing media during maximal kallikrein-induced contractions or after uterine tissue was incubated with high concentrations of the enzyme in the presence of SQ 20881, a kininase II inhibitor. The data suggest that uterine contraction produced by a homologous kallikrein does not involve kinin formation but results from an action of this serine proteinase upon other accessible systems coupled to the contractile response.
title: Musculoskeletal manifestations of sickle cell disease; a pictorial review
Creators: name: Papagiorcopulo, Carla
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Musculoskeletal system
subject: Musculoskeletal bone
subject: Conventional radiography
subject: MR
subject: CT
subject: Education
subject: Haematologic diseases
subject: Ischaemia / Infarction
subject: Infection

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1. Review the manifestationsof musculoskeletal complications ofsickle cell disease and their pathophysiology 2. Describe the imaging findings of the common musculoskeletal manifestations of sickle cell disease 3. Understand the difficulties that...
Long-term effects of intensive glycemic and blood pressure control and fenofibrate use on kidney outcomes
Creators: name: Craven, T.E.
name: Pedley, C.F.
name: Buse, J.B.
name: Ismail-Beigi, F.
name: Simmons, D.L.
name: Mottl, A.K.
name: Sigal, R.J.
name: Papademetriou, V.
name: Mychaleckyj, J.C.
name: Katz, L.
Publisher: name: American Society of Nephrology
Year: 2018

description: Background and objectives In people with type 2 diabetes, aggressive control of glycemia, BP, and lipids have resulted in conflicting short-term (<5 years) kidney outcomes. We aimed to determine the long-term kidney effects of these interventions. Design, setting, participants, & measurements The Action to Control Cardiovascular Risk in Diabetes (ACCORD) was a multifactorial intervention study in people with type 2 diabetes at high risk for cardiovascular disease (n=10,251), to examine the effects of intensive glycemic control (hemoglobin A1c <6.0% versus 7%-7.9%), BP control (systolic BP <120 mm Hg versus <140 mm Hg) or fenofibrate versus placebo added to simvastatin on cardiovascular events and death. The glycemia trial lasted 3.7 years and participants were followed for another 6.5 years in ACCORDION, the ACCORD Follow-On Study. The post hoc primary composite kidney outcome was defined as incident macroalbuminuria, creatinine doubling, need for dialysis, or death by any cause. Cox proportional hazards regression estimated the effect of each intervention on the composite outcome and individual components. In secondary outcome analyses, competing risk regression was used to account for the risk of death in incident kidney outcomes. Analyses were adjusted for sociodemographics, randomization groups, and clinical factors. Results There were 988 cases of incident macroalbuminuria, 954 with doubling of creatinine, 351 requiring dialysis, and 1905 deaths. Hazard ratios (HRs) for the composite outcome with intensive glycemic, BP control, and fenofibrate use compared with standard therapy were 0.92 (95% confidence interval [95% CI], 0.86 to 0.98), 1.16 (95% CI, 1.05 to 1.28), and 1.16 (95% CI, 1.06 to 1.27). Multivariable, secondary outcome analyses showed that in the glycemia trial, only macroalbuminuria was significantly decreased (HR, 0.68; 95% CI, 0.59 to 0.77). In the BP and lipid trials, only creatinine doubling was affected (HR, 1.64; 95% CI, 1.30 to 2.06 and HR, 2.00; 95% CI, 1.61 to 2.49, respectively). Conclusions In people with type 2 diabetes at high risk for cardiovascular disease, intensive glycemic control may result in a long-term reduction in macroalbuminuria; however, intensive BP control and fenofibrates may increase the risk for adverse kidney events.
title: Normal MR anatomy of the prostate gland
Creators: name: Sklinda, Katarzyna
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Urinary Tract / Bladder
subject: Pelvis
subject: Genital / Reproductive system male
subject: MR
subject: Education
subject: Normal variants
subject: Education and training
subject: Cancer

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: The aim of this poster is to review the prostate gland normal anatomy using MR imaging. The complexity of this anatomical structure makes the male pelvis a radiological challenge. This presentation gives a detailed description of the anatomy and...
An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation
Creators: name: Whitehead, W.E.
name: Palsson, O.S.
name: Aziz, I.
name: Simrén, M.
name: Törnblom, H.
Publisher: name: Taylor and Francis Ltd
Year: 2020

description: Introduction: Chronic constipation is highly prevalent, affecting between 10% and 15% of the population. The Rome IV criteria categorizes disorders of chronic constipation into four subtypes: (a) functional constipation, (b) irritable bowel syndrome with constipation, (c) opioid-induced constipation, and (d) functional defecation disorders, including inadequate defecatory propulsion and dyssynergic defecation. The initial management approach for these disorders is similar, focusing on diet, lifestyle and the use of standard over-the-counter laxatives. If unsuccessful, further therapy is tailored according to subtype. Areas covered: This review covers the definition, epidemiology, diagnostic criteria, investigations and management of the Rome IV disorders of chronic constipation. Expert opinion: By adopting a logical step-wise approach toward the diagnosis of chronic constipation and its individual subtypes, clinicians have the opportunity to tailor therapy accordingly and improve symptoms, quality of life, and patient satisfaction.
title: Protocol for Preoperative Subcortical Mapping with Fiber Tracking with Diffusion Tensor Imaging for Tumors in Eloquent Areas
Creators: name: Ordonez-Rubiano, Edgar
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: CNS
subject: Neuroradiology brain
subject: MR-Diffusion/Perfusion
subject: Safety
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To describe seeding ROIs to reproduce the language fascicles separately for preoperative mapping with DTI...
Sensitivity of multiplicity fluctuations to freeze-out conditions in heavy ion collisions
Creators: name: Alba, Paolo
name: Bellwied, Rene
name: Bluhm, Marcus
name: Sarti, Valentina Mantovani
name: Nahrgang, Marlene
name: Ratti, Claudia
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We study the sensitivity of the higher-order moments of produced particle multiplicity distributions to the chemical freeze-out parameters in relativistic heavy ion collisions using the Hadron Resonance Gas (HRG) model. We compare the obtained sensitivity level to the one extracted from the ratios of particle yields. We find that, for certain final state hadrons, the fluctuation measurements add significant information to the determination of the hadro-chemical freeze-out properties of the deconfined phase of matter obtained at RHIC and the LHC.
description: 7 pages, 7 figures
(101295) Maria Jane Latcham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Comportamento do consumidor: modelos teóricos cognitivos frente ao modelo comportamental Behavioral Perspective Model (BPM)
Creators: name: Gomes, Marizangela
Publisher: name: Zenodo
Year: 2022
Subjects: Construtos
Variáveis
Consumidor

description: O presente estudo tem como objetivo principal relatar, por meio da literatura, os conceitos e construtos que ganharam espaço nos modelos teóricos sobre comportamento do consumidor. Este ensaio identificará, portanto, os principais conceitos e construtos utilizados em modelos teóricos cognitivos e o modelo comportamental Behavioral Perspective Model. Para tanto, apresenta-se as contribuições conceituais sobre construtos, seguido dos principais modelos teóricos cognitivos sobre comportamento do consumidor; o modelo Nicosia, o modelo Howard-Sheth, e o modelo Engel, Blackwell e Miniard, assim como o modelo comportamental Behavioral Perspective Model (BPM). O ensaio traz contribuições acerca da percepção de que há uma predominância de conceitos mentais nos modelos cognitivos e uma fragilidade na definição dos construtos que o originam. Dentro da abordagem comportamental identifica-se uma ênfase nos eventos observáveis para originarem construtos que analisem o comportamento do consumidor por meio de variáveis com maior força de mensuração.

description: Ensaio
title: Contribution of Elastography in characterizing Bi-Rads 3 and 4 breast lesions.
Creators: name: Ali, Amal
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Breast
subject: Elastography
subject: Biopsy
subject: Pathology

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Breast cancer incidence is at a continuous rise explaining the necessity of early breast cancer detection (1). Breast tissue is considered an elastic tissue. This feature makes physical examination by palpation a sensitive method to detect...
Fecal Incontinence Diagnosed by the Rome IV Criteria in the United States, Canada, and the United Kingdom
Creators: name: van Tilburg, M.A.L.
name: Heymen, S.
name: Simren, M.
name: Busby-Whitehead, J.
name: Whitehead, W.E.
name: Sperber, A.D.
name: Palsson, O.S.
Publisher: name: W.B. Saunders
Year: 2020

description: Background & Aims: The diagnostic criteria for fecal incontinence (FI) were made more restrictive in the Rome IV revision. We aimed to determine the characteristics of FI patients defined by the Rome IV criteria, assess how FI frequency and amount affect quality of life, identify risk factors, and compare prevalence values among countries. Methods: We performed an internet-based survey of 5931 subjects in the United States, Canada, and the United Kingdom, from September to December 2015. Subjects were stratified by country, sex, and age. Responders answered questions about diagnosis, health care use, and risk factors. We performed multivariate linear regression analysis to identify risk factors for FI. Results: FI was reported by 957 subjects (16.1%) but only 196 (3.3%) fulfilled the Rome IV criteria. Frequency of FI was less than twice a month for 672/957 subjects (70.2%) and duration was less than 6 months for 285/957 subjects (29.8%). Quality of life was significantly impaired in all subjects with FI compared to subjects with fecal continence. The strongest risk factors for FI were diarrhea, urgency to defecate, and abdominal pain. FI was more prevalent in the United States than in the United Kingdom. Between-country differences were due to less diarrhea and urgency in the United Kingdom. Conclusions: Rome IV FI prevalence is lower than previous estimates because the new criteria exclude many individuals with less frequent or short duration FI. These excluded patients have impaired quality of life. It might be appropriate to make a diagnosis of FI for all patients with FI ≥2 times in 3 months and to provide additional information on frequency, duration, and amount of stool lost to assist clinicians in treatment selection.
(101296) Charles Arthur Latcham
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Introduction of New Coconut Germplasm Tissue Culture-derived Plantlets: The Case of Saint Lucia
Creators: name: Veira, Andrea
name: Seepersad, Govind
name: Cherry, Marnus
name: Veira, Andrea
name: Seepersad, Govind
name: Cherry, Marnus
Publisher: name: Unknown
Year: 2022
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Crop Production/Industries
subject: Coconut planting material
subject: Mexica Malayan Dwarfs
subject: Somatic embryogenesis
subject: Coconut industry
subject: IPPC
subject: Importation of planting material

description: The international competitiveness of coconut farmers rests on the quantum of fruit juice produced per unit area, per unit time and on the cost of production. In order to compete on the beverage market of which St Lucia is a part, coconut germplasm was imported to increase farmers’ productivity. The country imported approximately 9,100 coconut tissue-culture derived plantlets from Mexico between 2016 and 2018 and undertook acclimatization and field establishment. This study looks at the technical guidelines for the transboundary movement of coconut-specific germplasm into St. Lucia and the experiences of field establishment. While it is still early to measure the effectiveness of this technological input into the industry, the study examines the application of Sanitary and Phytosanitary (SPS) Measures in the transboundary movement of the tissue culture-derived coconut plantlets and the shortfalls of these established regulations. There was a low rate of acclimatization and survival of the plantlets because of delays in trans-shipments at various ports, cargo transportation schedules and weaning and hardening protocol weaknesses. The study found need for improvement in St. Lucia’s SPS capabilities for the transboundary movement of coconut germplasm and coconut agronomy skills as well as alternative solutions of increasing availability of planting materials for coconut.
Analysis of gamma-ray burst duration distribution using mixtures of skewed distributions
Creators: name: Tarnopolski, Mariusz
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: Two classes of GRBs have been confidently identified thus far and are prescribed to different physical scenarios -- NS-NS or NS-BH mergers, and collapse of massive stars, for short and long GRBs, respectively. A third, intermediate in duration class, was suggested to be present in previous catalogs, such as BATSE and $Swift$, based on statistical tests regarding a mixture of two or three log-normal distributions of $T_{90}$. However, this might possibly not be an adequate model. This paper investigates whether the distributions of $\log T_{90}$ from BATSE, $Swift$, and $Fermi$ are described better by a mixture of skewed distributions rather than standard Gaussians. Mixtures of standard normal, skew-normal, sinh-arcsinh and alpha-skew-normal distributions are fitted using a maximum likelihood method. The preferred model is chosen based on the Akaike information criterion. It is found that mixtures of two skew-normal or two sinh-arcsinh distributions are more likely to describe the observed duration distribution of $Fermi$ than a mixture of three standard Gaussians, and that mixtures of two sinh-arcsinh or two skew-normal distributions are models competing with the conventional three-Gaussian in the case of BATSE and $Swift$. Based on statistical reasoning, existence of a third (intermediate) class of GRBs in $Fermi$ data is rejected, and it is shown that other phenomenological models may describe the observed $Fermi$, BATSE, and $Swift$ duration distributions at least as well as a mixture of standard normal distributions.
description: 9 pages, 7 figures, 3 tables; matches the version accepted by MNRAS. arXiv admin note: text overlap with arXiv:1602.02363
title: Cardiac MRI contribution in ischemic heart diseases
Creators: name: Attia, Monia
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Cardiac
subject: Cardiac
subject: MR
subject: MR-Functional imaging
subject: Imaging sequences
subject: Ischaemia / Infarction

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Ischemic cardiomyopathy is one of the major health problems worldwide, playing a significant role in the mortality nowadays. It is a condition characterized by the presence of myocardial ischemia, either associated or not with fibrosis caused by...
Testing eccentricity pumping mechanisms to model eccentric long period sdB binaries with MESA
Creators: name: Vos, Joris
name: Østensen, Roy
name: Marchant, Pablo
name: Van Winckel, Hans
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Hot subdwarf-B stars in long-period binaries are found to be on eccentric orbits, even though current binary-evolution theory predicts those objects to be circularised before the onset of Roche-lobe overflow (RLOF). We aim to find binary-evolution mechanisms that can explain these eccentric long-period orbits, and reproduce the currently observed period-eccentricity diagram. Three different processes are considered; tidally-enhanced wind mass-loss, phase-dependent RLOF on eccentric orbits and the interaction between a circumbinary disk and the binary. The binary module of the stellar-evolution code MESA (Modules for Experiments in Stellar Astrophysics) is extended to include the eccentricity-pumping processes. The effects of different input parameters on the final period and eccentricity of a binary-evolution model are tested with MESA. The end products of models with only tidally-enhanced wind mass-loss can indeed be eccentric, but these models need to lose too much mass, and invariably end up with a helium white dwarf that is too light to ignite helium. Within the tested parameter space, no sdBs in eccentric systems are formed. Phase-dependent RLOF can reintroduce eccentricity during RLOF, and could help to populate the short-period part of the period-eccentricity diagram. When phase-dependent RLOF is combined with eccentricity pumping via a circumbinary disk, the higher eccentricities can be reached as well. A remaining problem is that these models favour a distribution of higher eccentricities at lower periods, while the observed systems show the opposite. The models presented here are potentially capable of explaining the period-eccentricity distribution of long-period sdB binaries, but further theoretical work on the physical mechanisms is necessary.
description: 18 pages, 9 figures, accepted for publication in A&A
(101294) Mary Washbourne Jackson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Hypnosis and Cognitive Behavioral Therapies for the Management of Gastrointestinal Disorders
Creators: name: Ballou, S.
name: Palsson, O.S.
Publisher: name: Springer
Year: 2020

description: Purpose of Review: To review the nature, current evidence of efficacy, recent developments, and future prospects for cognitive behavioral therapy (CBT) and gut-directed hypnotherapy, the two best established psychological interventions for managing gastrointestinal (GI) disorders. Recent Findings: New large randomized controlled trials are showing that cost-effective therapy delivery formats (telephone-based, Internet-based, fewer therapist sessions, or group therapy) are effective for treating GI disorders. Summary: CBT and hypnotherapy can produce substantial improvement in the digestive tract symptoms, psychological well-being, and quality of life of GI patients. However, they have long been hampered by limited scalability and significant cost, and only been sufficiently tested for a few GI health problems. Through adoption of more cost-effective therapy formats and teletherapy, and by expanding the scope of efficacy testing to additional GI treatment targets, these interventions have the potential to become widely available options for improving clinical outcomes for patients with hard-to-treat GI disorders.
Measurement of Lifetimes in 23Mg
Creators: name: Kirsebom, O. S.
name: Bender, P.
name: Cheeseman, A.
name: Christian, G.
name: Churchman, R.
name: Cross, D. S.
name: Davids, B.
name: Evitts, L. J.
name: Fallis, J.
name: Galinski, N.
name: Garnsworthy, A. B.
name: Hackman, G.
name: Lighthall, J.
name: Ketelhut, S.
name: Machule, P.
name: Miller, D.
name: Nobs, C. R.
name: Pearson, C. J.
name: Rajabali, M. M.
name: Radich, A. J.
name: Rojas, A.
name: Ruiz, C.
name: Sanetullaev, A.
name: Unsworth, C. D.
name: Wrede, C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Several lifetimes in 23Mg have been determined for the first time using the Doppler-shift attenuation method. A Monte Carlo simulation code has been written to model the gamma-ray line shape. An upper limit of 12 fs at the 95% C.L. has been obtained for the astrophysically important 7787 keV state.
Toward an Appropriate Theoretical Framework for Agricultural Development Planning and Policy
Creators: name: Beckford, George
name: Beckford, George
Publisher: name: Unknown
Year: 2022
Subjects: Agricultural and Food Policy

description: In order to be elective, development planning and policy need to be in- formed by relevant theory. This paper at first argues that, in many important respects, the current body of agricultural development theory inadequately represents the Caribbean situation. In so far as this hypothesis is correct, it implicitly provides a partial explanation for the failure to get agriculture moving in spite of substantial government intervention and assistance in most territories of the region. It also sets the stage for the second objective of the paper: to outline some of the steps required for developing an appropriate theoretical framework and to place this selection of papers in the perspective of these considerations.
title: Bone metastases in the peripheral skeleton and impeding fractures: Review of augmented osteoplasty techniques
Creators: name: Velonakis, George
Publisher: name: European Congress of Radiology
Year: 2017
Subjects: subject: Instrumentation
subject: Fluoroscopy
subject: CT
subject: Musculoskeletal system
subject: Musculoskeletal bone
subject: Interventional non-vascular
subject: Cancer
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To introduce Radiologists into the different Interventional augmented osteoplasty techniques for prevention of impeding pathologic fracture and pain reduction To discuss potential advantages of each technique To learn about proper patient selection...