cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The changing meaning of gene therapy : exploring the significance of curative genetic research in the narratives of families with Duchenne muscular dystrophy
Creators: name: Condin, Christopher J.
Publisher: name: University of British Columbia
Year: 2010

description: Gene therapy and stem cell therapy are symbols of a futuristic age in biomedicine. These experimental treatments have led to speculation that many presently untreatable diseases will soon be cured. However, there has been relatively little study of how this conjecture affects families experiencing a serious genetic illness. This study is based on interviews conducted with ten families in which a child has Duchenne muscular dystrophy (DMD) - a lethal childhood disorder. Parents were asked to relate their hopes and expectations for advanced genetic research, and its relevance in their everyday lives. Building on a tradition of scholarship in the social sciences that examines how individuals make sense of their experiences with illness through narrative, I show how the field of gene therapy research is implicated in the process of emplotting and telling a story about DMD and remodifying it as circumstances change. I point to some of the ways in which the significance of curative genetic research for parents varies over time. I illustrate how the field of genetics serves as a narrative device, taking on different meanings depending on its place in the story parents tell about their child's disease. I also show how parents learn about genetic research mainly by participating in socially constituted communities of practice, a process I liken to the concept of legitimate peripheral participation. This study contributes to a growing debate about whether lay-actors are sufficiently informed vis-a-vis the risks and benefits involved in experimental medical research, by showing how studies of "therapeutic misconception" can overlook the broader picture. Attention is drawn to the manner in which research is situated in parents' personal biographies and everyday lives, to the socially constituted ways in which parents come to acquire knowledge about and construct expectations for the field of genetics, and to the multiple places that it occupies in the stories they construct and tell about their child's chronic illness. Brief overviews of the historical trajectory of gene therapy research, and recent developments in curative medical research related to DMD are also provided.
Adoção Sequencial de Tecnologia Pós-colheita Aplicada à Cafeicultura em Viçosa (MG)
Creators: name: Pereira, Matheus Wemerson Gomes
name: Teixeira, Erly Cardoso
name: Lima, Joao Eustaquio De
name: Pereira, Matheus Wemerson Gomes
name: Teixeira, Erly Cardoso
name: Lima, Joao Eustaquio De
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: technology adoption
subject: coffee
subject: Logit Multinomial
subject: relative risk ratio
subject: Minas Gerais.

description: The process of tecnology adoption in agriculture is fundamentally important for increasing productivity and improving the quality of agricultural products. The objective of this study is to evaluate the factors that determine the technological adoption of post-harvest coffee employed in Viçosa (MG) in the year of 2007. The results indicate that the sequential model is more appropriate for the analysis and the most important determinants for the adoption of higher levels of post-harvest technology are association, profitability, training, education, credit, stock of capital, and years at school. The most important marginal effects for the adoption of higher levels of post-harvest technology are association, training, credit and profitability.
MIKRO VA KICHIK GIDROELEKTROSTANTSIYALARDAN FOYDALANISH VA ULARNING AFZALLIKLARI.
Creators: name: Mirzayev, Sardorbek
name: Азимов, Араббой
name: Abobakirov, Rustambek
name: Axmadjonov, Raximjon
Publisher: name: Zenodo
Year: 2024

description: Kichik GES yoki kichik gidroelektrostantsiya (SHPP) - nisbatan oz miqdorda elektr energiyasi ishlab chiqaradigan va quvvati 1 dan 3000 kVt gacha bo'lgan GES negizida qurilgan GES.
Deciphering the recently discovered tetraquark candidates around 6.9 GeV
Creators: name: Sonnenschein, Jacob
name: Weissman, Dorin
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Recently a novel hadronic state of mass 6.9 GeV, that decays mainly to a pair of charmonia, was observed in LHCb. The data also reveals a broader structure centered around 6490 MeV and suggests another unconfirmed resonance centered at around 7240 MeV, very near to the threshold of two doubly charmed $Ξ_{cc}$ baryons. We argue in this note that these exotic hadrons are genuine tetraquarks and not molecules of charmonia. It is conjectured that they are V-baryonium tetraquarks, namely, have an inner structure of a baryonic vertex with a $cc$ diquark attached to it, which is connected by a string to an anti-baryonic vertex with a $\bar c \bar c$ anti-diquark. We examine these states as the analogs of the states $Ψ(4360)$ and $Y(4630)$/$Ψ(4660)$ which are charmonium-like tetraquarks. One way to test these claims is by searching for a significant decay of the state at 7.2 GeV into $Ξ_{cc}\overlineΞ_{cc}$. Such a decay would be the analog of the decay of the state $Y(4630)$ into to $Λ_c\overlineΛ_c$. We further argue that there should be trajectories of both orbital and radial excited states of the $X(6900)$. We predict their masses. It is possible that a few of these states have already been seen by LHCb.
description: v1: 22 pages, 4 figures v2: typos corrected, minor additions and references added. 22 pages, v3: references added. 22 pages
As Consequências dos Acordos de Livre Comércio Sobre o Setor de Lácteos no Brasil
Creators: name: Alvim, Augusto Mussi
name: Alvim, Augusto Mussi
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: Mixed Complementary Problem (MCP)
subject: partial equilibrium models
subject: dairy sector
subject: and multiregional and multi-product analysis.

description: This paper discusses the main effects of free trade agreements on the dairy sector in Brazil. A partial equilibrium model formulated as a Mixed Complementary Problem (MCP) is used to provide some numerical examples of changes (potential gain and losses) in terms of production, trade and welfare in each scenario. This model also considers a multiregional and a multi-product dimension, which permits to analyze the impact of trade liberalization upon different regions and diverse processed dairy products.
title: Spatio-temporal prioritized planning
Creators: name: Binder, Benjamin
Publisher: name: TU Wien
Year: 2017
Subjects: subject: autonomes Fahren
subject: Navigieren
subject: motion control
subject: Robotik
subject: Pfadplanung
subject: autonomous driving
subject: navigation
subject: motion control
subject: robotic
subject: path-planning

description: Using robot fleets have gained popularity in recent years in industrial logistics applications because of their flexible field of application. Therefore, the issue arises how to coordinate these robots. A commonly used approach to this problem is Prioritized Planning, where a coordinator plans all robot's routes sequentially avoiding already planned ones. This thesis presents a new approach for prioritized multi robot path planning. The proposed planner works centralized and generates synchronized and deadlock-free routes for robots. Applying search algorithms on pixel-maps is expensive, therefore, pixel-maps are reduced to search graphs using voronoi distillation. A single robot path planner for use inside a prioritized multi robot path planner is designed. This single robot path planner constrains the creation of new routes by adding already planned ones to the used search graph. To find solutions in this graph the single robot path planner is able to take temporal and spacial constraints into account. Furthermore, potential collisions and deadlocks between robots are avoided by extending the search graph with additional segments if a collision is detected. The global multi robot path planner includes a priority and speed rescheduler as well, to solve specific scenarios which are hard to solve using prioritized path planning. Because the routes are generated time-dependently, they are post-processed to add synchronization markers in form of preconditions for every robot. These preconditions have to be met before a robot is allowed to enter a segment. Selected scenarios with multiple robots are used to compare the proposed planner with state of the art approaches in a simulated environment. Also scenarios are shown to be solvable with the proposed planner, which are not solvable with currently used approaches.
Causal sites as quantum geometry
Creators: name: Christensen, J. Daniel
name: Crane, Louis
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Category Theory (math.CT)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We propose a structure called a causal site to use as a setting for quantum geometry, replacing the underlying point set. The structure has an interesting categorical form, and a natural "tangent 2-bundle," analogous to the tangent bundle of a smooth manifold. Examples with reasonable finiteness conditions have an intrinsic geometry, which can approximate classical solutions to general relativity. We propose an approach to quantization of causal sites as well.
description: 21 pages, 3 eps figures; v2: added references; to appear in JMP
Study of a Neutrino Mass Texture Generated in Supergravity with Bilinear R-Parity Violation
Creators: name: Diaz, Marco A.
name: Mora, Clemencia
name: Zerwekh, Alfonso R.
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study a particular texture of the neutrino mass matrix generated in supergravity with bilinear R-Parity violation. The relatively high value of $\tanβ$ makes the one-loop contribution to the neutrino mass matrix as important as the tree-level one. The atmospheric angle is nearly maximal, and its deviation from maximal mixing is related to the smallness of the ratio between the solar and atmospheric mass scales. There is also a common origin for the small values of the solar and reactor angles, but the later is much smaller due the large mass ratio between the lightest two neutrinos. There is a high dependence of the neutrino mass differences on the scalar mass $m_0$ and the gaugino mass $M_{1/2}$, but a smaller one of the mixing angles on the same sugra parameters. Measurements of branching ratios for the neutralino decays can give important information on the parameters of the model. There are good prospects at a future Linear Collider for these measurements, but a more detailed analysis is necessary for the LHC.
description: 21 pages, 9 figures
Quiescent observations of the WZ Sge type dwarf nova PQ Andromedae
Creators: name: Schwarz, Greg J.
name: Barman, Travis
name: Silvestri, Nicole
name: Szkody, Paula
name: Starrfield, Sumner
name: Vanlandingham, Karen
name: Wagner, R. Mark
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have obtained time series optical spectra of the cataclysmic variable PQ And in quiescence. The spectra show a white dwarf continuum with narrow Balmer emission superimposed over strong Balmer absorption. The emission lines have blue and red components whose strength changes with time. An analysis of the H$α$ emission line implies a short orbital period below the period gap. Given its lack of accretion disk features, its large and infrequent outbursts, and an orbital period below the period gap, PQ And is probably a low accretion rate object similar to WZ Sge. In addition, white dwarf model fits imply that PQ And is an excellent ZZ Cet candidate.
description: AASTeX. 8 pages, 6 figures, 3 tables. Accepted to the PASP
Gaia 18dvy: a new FUor in the Cygnus OB3 association
Creators: name: Szegedi-Elek, E.
name: Ábrahám, P.
name: Wyrzykowski, L.
name: Kun, M.
name: Kóspál, A.
name: Chen, L.
name: Marton, G.
name: Moór, A.
name: Kiss, Cs.
name: Pál, A.
name: Szabados, L.
name: Varga, J.
name: Varga-Verebélyi, E.
name: Andreas, C.
name: Bachelet, E.
name: Bischoff, R.
name: Bódi, A.
name: Breedt, E.
name: Burgaz, U.
name: Butterley, T.
name: Čepas, V.
name: Damljanovic, G.
name: Gezer, I.
name: Godunova, V.
name: Gromadzki, M.
name: Gurgul, A.
name: Hardy, L.
name: Hildebrandt, F.
name: Hoffmann, S.
name: Hundertmark, M.
name: Ihanec, N.
name: Janulis, R.
name: Kalup, Cs.
name: Kaczmarek, Z.
name: Könyves-Tóth, R.
name: Krezinger, M.
name: Kruszyńska, K.
name: Littlefair, S.
name: Maskoliūnas, M.
name: Mészáros, L.
name: Mikołajczyk, P.
name: Mugrauer, M.
name: Netzel, H.
name: Ordasi, A.
name: Pakštienė, E.
name: Rybicki, K. A.
name: Sárneczky, K.
name: Seli, B.
name: Simon, A.
name: Šiškauskaitė, K.
name: Sódor, Á.
name: Sokolovsky, K. V.
name: Stenglein, W.
name: Street, R.
name: Szakáts, R.
name: Tomasella, L.
name: Tsapras, Y.
name: Vida, K.
name: Zdanavičius, J.
name: Zieliński, M.
name: Zieliński, P.
name: Ziółkowska, O.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present optical-infrared photometric and spectroscopic observations of Gaia18dvy, located in the Cygnus OB3 association at a distance of 1.88 kpc. The object was noted by the Gaia alerts system when its lightcurve exhibited a $\gtrsim$4 mag rise in 2018-2019. The brightening was also observable at mid-infared wavelengths. The infrared colors of Gaia18dvy became bluer as the outburst progressed. Its optical and near-infrared spectroscopic characteristics in the outburst phase are consistent with those of bona fide FU Orionis-type young eruptive stars. The progenitor of the outburst is probably a low-mass K-type star with an optical extinction of $\sim$3 mag. A radiative transfer modeling of the circumstellar structure, based on the quiescent spectral energy distribution, indicates a disk with a mass of $4{\times}10^{-3}\,M_{\odot}$. Our simple accretion disk modeling implies that the accretion rate had been exponentially increasing for more than 3 years until mid-2019, when it reached a peak value of $6.9 \times 10^{-6}\,M_{\odot}$yr$^{-1}$. In many respects, Gaia18dvy is similar to the FU Ori-type object HBC 722
description: 11 pages, 7 figures, accepted for publication in ApJ
Corporate Social Responsibility and Management of Environment
Creators: name: Raj, Nitesh
Publisher: name: figshare
Year: 2020
Subjects: Economics

description: These days when the Central Government is interested in Make in India campaign the scale of management or evaluation of business is not as if used to be about fifty years ago. At that time only that business organization was considered good which was earning profit for its owner but today the situation is absolutely changed. Today business has to look to the interest of many other stakeholders along with the interest of the owner. The employees- line and top management, consumers, suppliers, competitors, government, community, environment and even the world happen to be the other stakeholders. This responsibility of business, which includes the satisfaction of these parties along with the owner, is called the social responsibility of business or corporate sectors.
Abordagem Conexionista para Análise Espacial Exploratória de Dados Socioeconômicos de Territórios Rurais
Creators: name: Silva, Marcos Aurélio Santos Da
name: Siqueira, Edmar Ramos De
name: Teixeira, Olívio Alberto
name: Silva, Marcos Aurélio Santos Da
name: Siqueira, Edmar Ramos De
name: Teixeira, Olívio Alberto
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: self-organizing maps
subject: visualization
subject: clustering
subject: territory.

description: The use of multivariate analysis techniques for exploratory spatial study of rural geospatial data has being useful in territorial characterization and typology. Connectionist approach is a very efficient computational method for these tasks, mainly the Self-Organizing Map (SOM). Through the use of SOM clustering and data visualization can be conducted simultaneously. This paper assesses the capacity of SOM algorithm in the task of exploratory multisource data analysis for local aggregation verification in the Center-South Rural Territory of Sergipe State, Brazil. Results shown that, despite the homogeneity of the region, there are significant differences among subgroups of municipalities that compose the territory.
Vacuum stability and spontaneous violation of the lepton number at low energy scale in a model for light sterile neutrinos
Creators: name: Pinheiro, João Paulo
name: Pires, C. A. de S.
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: It is well known that the Standard Model of the Electroweak interactions rests on a metastable vacuum. This can only be fixed by means of new physics. Presently neutrino physics provides the most intriguing framework to formulate new physics. This is so because, in addition to the problem of the lightness of the active standard neutrinos, currently MiniBooNE experimental result may be indicating that sterile neutrinos exist and are light, too. In this case, it is reasonable to expect that the framework that yields light active and sterile neutrinos could stabilize the vacuum, too. In order to achieve this goal, we consider an extension of the standard model which involves new fermions in the form of right-handed neutrinos ($ν_R$) and new scalars in the form of triplet ($Δ$) and singlet ($σ$). Within this framework, tiny masses are obtained when we consider that lepton number is spontaneously broken at low energy scale which means that $Δ$ and $σ$, both, develop very small vacuum expectation values. We investigate if this setting leads to a stable vacuum. For this we obtain the whole set of conditions over the Quartic Terms of the Potential that ensures that the model is Bounded From Below(BFB) and evaluate the RGE-evolution of the self coupling of the Higgs. We show that in such a scenario the Quartic Coupling $Φ^T ΔΦσ$, where $Φ$ is the standard Higgs doublet, is responsible for the stability of the Electroweak Vacuum up to Planck scale. We also extract constraints over the parameters of the Potential by means of Lepton Flavor Violating(LFV) processes and from invisible decay of the standard-like Higgs.
description: 20 pages, 2 figures
On the Aggregation of Inertial Particles in Random Flows
Creators: name: Mehlig, B.
name: Wilkinson, M.
name: Duncan, K.
name: Weber, T.
name: Ljunggren, M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: We describe a criterion for particles suspended in a randomly moving fluid to aggregate. Aggregation occurs when the expectation value of a random variable is negative. This random variable evolves under a stochastic differential equation. We analyse this equation in detail in the limit where the correlation time of the velocity field of the fluid is very short, such that the stochastic differential equation is a Langevin equation.
description: 16 pages, 2 figures
title: Interactive shape detection in Out-Of-Core point clouds for assisted user interactions
Creators: name: Rainer, Bernhard
Publisher: name: TU Wien
Year: 2017
Subjects: subject: point-based rendering
subject: out-of-core rendering
subject: shape detection
subject: point-based rendering
subject: out-of-core rendering
subject: shape detection

description: This thesis presents a semi-automated method for shape detection in out-of-core point clouds. Rather than performing shape detection on the entire point cloud at once, a user-controlled interaction determines the region that is to be segmented next. By keeping the size of the region and the number of points small, the algorithm produces meaningful results within a fraction of a second. Thus, the user is presented immediately with feedback on the local geometry. As modern point clouds can contain billions of points and the memory capacity of consumer PCs is usually insufficient to hold all points in memory at the same time, a level-of-detail data structure is used to store the point cloud on the hard disc, and data is loaded into memory only on use. This data structure partitions the point cloud into small regions, each containing around 5000 points, that are used for rendering and shape detection. Interacting with point clouds is a particularly demanding task. A precise selection of a region of interest, using the two-dimensional lasso interaction, often needs multiple view changes and subsequent improvements. This thesis proposes improvements to the lasso interaction, by performing selection only on the set of points that are approximated by a detected shape. Thus, the selection of undesired points in the fore- and background is reduced. Point picking is improved as well by the use of a detected shape, such that only points that are approximated by this shape are pick-able. The result of this thesis is an application that allows the user to view point clouds with millions of points. It also provides a novel interaction technique for quick local shape detection as well as shape-assisted interactions that utilize this local semantic information to improve the user's workflow.
Mg II Absorption Systems in SDSS QSO Spectra
Creators: name: Nestor, D. B.
name: Turnshek, D. A.
name: Rao, S. M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the results of a MgII absorption-line survey using QSO spectra from the SDSS EDR. Over 1,300 doublets with rest equivalent widths greater than 0.3Åand redshifts $0.366 \le z \le 2.269$ were identified and measured. We find that the $\lambda2796$ rest equivalent width ($W_0^{\lambda2796}$) distribution is described very well by an exponential function $\partial N/\partial W_0^{\lambda2796} = \frac{N^*}{W^*} e^{-\frac{W_0}{W^*}}$, with $N^*=1.187\pm0.052$ and $W^*=0.702\pm0.017$Å. Previously reported power law fits drastically over-predict the number of strong lines. Extrapolating our exponential fit under-predicts the number of $W_0 \le 0.3$Åsystems, indicating a transition in $dN/dW_0$ near $W_0 \simeq 0.3$Å. A combination of two exponentials reproduces the observed distribution well, suggesting that MgII absorbers are the superposition of at least two physically distinct populations of absorbing clouds. We also derive a new redshift parameterization for the number density of $W_0^{\lambda2796} \ge 0.3$Ålines: $N^*=1.001\pm0.132(1+z)^{0.226\pm0.170}$ and $W^*=0.443\pm0.032(1+z)^{0.634\pm 0.097}$Å. We find that the distribution steepens with decreasing redshift, with $W^*$ decreasing from $0.80\pm0.04$Åat $z=1.6$ to $0.59\pm0.02$Åat $z=0.7$. The incidence of moderately strong MgII $\lambda2796$ lines does not show evidence for evolution with redshift. However, lines stronger than $\approx 2$Åshow a decrease relative to the no-evolution prediction with decreasing redshift for $z \lesssim 1$. The evolution is stronger for increasingly stronger lines. Since $W_0$ in saturated absorption lines is an indicator of the velocity spread of the absorbing clouds, we interpret this as an evolution in the kinematic properties of galaxies from moderate to low z.
description: 50 pages, 26 figures, accepted for publication in ApJ
A Precariedade do Transporte Rodoviário Brasileiro para o Escoamento da Produção de Soja do Centro-Oeste: situação e perspectivas
Creators: name: Correa, Vivian Helena Capacle
name: Ramos, Pedro
name: Correa, Vivian Helena Capacle
name: Ramos, Pedro
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: transportation infrastructure
subject: roads
subject: soybean
subject: competition

description: The Center-Western of Brazil is known to be a soy production center. At the beginning of the 80’s, because of a governmental fiscal crises, the Brazilian road infrastructure and conservation lost its investment, which reflected on the soy international competition. The main transportation used to deliver this product to the ports at the South and South-Eastern regions is the roads, highlighting the BR 163 and 364 road’s. Due to the inadequacy of the roads to the characteristics of this product, the long distances that have to be filled and also the bad conservation state of the Brazilian roads, 25% of this products sales are already accounted for internal transportation costs. There are a few alternatives appointed, such as road concessions and Public-Private Partnership (PPP). This paper analyzes the use of more efficient transportation modals. The conclusion is that the use of river and rail-road transportation modals are more efficient to transport the soy from the Center-Western region of the country, because of higher energetic and transportation efficiency due to the movement of higher density cargo at higher distances – what would reduce circulation costs.
Pecuária Familiar: a emergência de uma categoria social no Sul do Brasil
Creators: name: Porto, Rafael Gastal
name: Bezerra, Antônio Jorge Amaral
name: Porto, Victor Hugo Da Fonseca
name: Caldas, Nadia Velleda
name: Porto, Rafael Gastal
name: Bezerra, Antônio Jorge Amaral
name: Porto, Victor Hugo Da Fonseca
name: Caldas, Nadia Velleda
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agribusiness
subject: family farming
subject: beef cattle
subject: characterization

description: The objective of this paper was to identify and characterize farm family livestock in Bagé, Rio Grande do Sul State (Brazil), according to some criteria (land area, exploitation of approach, labour use, production objective, commercialization, intermediary, production integration, rural income and no-rural income). Direct interviews were conducted with family livestock farmers during May and June 2007 in the following locations: Palmas, Olhos D’Água, Coxilha do Haedo, Serrilhada and Santa Tecla, comprising a total of 40 interviews. Frequency analysis was used to examine the data. The research showed that 80% of the farmers explore areas of up to 200 hectares and 87,5% of the interviewees use exclusively family labour. As for the rural income, 70% of the cases earned less than two minimum wages. The results also showed the importance of off-farm income compared to total income, particularly from retirements and pensions, which are an essential instrument of social reproduction for the families.
A comprehensive RNAi screen for novel muscle-affecting genes in Caenorhabditis elegans identifies two paralogs, TO4A8.4 and F36F2.1, homologous to mammalian STARS
Creators: name: Dube, Nicholas
Publisher: name: University of British Columbia
Year: 2010

description: One of the fundamental features of metazoan development is myogenesis. A crucial step during myogenesis is the assembly and anchorage of the sarcomere, the essential repeat unit responsible for muscle contraction. In Caenorhabditis elegans, four phenotypic classes of muscle mutants defective in some aspect of muscle structure and function have been identified in mutagenesis screens: the uncoordinated (unc) class, typified by uncoordinated, slow or no movement, the muscle positioning defective (mup) class, the late embryonic lethal class known as paralyzed and arrested at two-fold stage (pat) mutants, and the class where animals are capable of wildtype development and movement but have disorganized muscle (dim). Using SAGE and microarray chip analysis we have identified 3395 non-ribosomal/ non-mitochondrial genes expressed in muscle. Using an RNAi feeding library, we screened this 'muscle expressome' for genes affecting sarcomere assembly, stability and/or function. Worms harboring an extrachromosomal array containing a myosin heavy chain gene, myo-3, fused in frame to green fluorescent protein (GFP) were fed bacteria expressing dsRNA corresponding to each gene within the muscle expressome. The progeny of these worms were examined for both overt phenotypes and mislocalization of myo-3::GFP. This approach proved to be a rapid and sensitive means to identify genes required to organize sarcomeric proteins into a highly ordered myofilament lattice and we identified 296 genes with defects in myo-3.:GFP localization in an initial screen and reconfirmed 121 of those genes in a rescreen. RNAi treated animals display an array of myofilament disruptions ranging from small aggregations of myo-3::GFP to large deposits, often accompanied by disorganization of the myofilaments. The high percentage of tested genes affecting muscle sarcomeres, 3.6%, likely reflects the fact that we have already enriched for genes expressed in this tissue. Many of the genes we have uncovered in this screen have human homologs for which little or nothing is known. Two paralogous proteins, T04A8.4 and F36F2.1, identified here share considerable homology to the human protein striated muscle activator of Rho signaling (STARS). I demonstrated that these proteins are expressed in body wall muscle and are required for proper actin and myosin localization in muscle. In addition, T04A8.4 appears to form a synthetic genetic interaction with mua-6 and unc-22 and F36F2.1 may form a genetic interaction with cdc-42.
R script files for 'Quantitative measurement of geodiversity uniqueness: research implications and conservation applications'
Creators: name: Alahuhta, Janne
name: García-Girón, Jorge
name: Hjort, Jan
name: Salminen, Henriikka
name: Tukiainen, Helena
name: Heino, Jani
Publisher: name: The Royal Society
Year: 2024
Subjects: classificationCode: 3705
subject: Geology
subject: FOS: Earth and related environmental sciences

description: Quantitative approaches are needed to complement qualitative explorations to identify sites with unique geodiversity and thereby guide geoconservation and geoheritage programmes. Here, we introduce the concept and associated index of ‘geodiversity uniqueness’. This index is based on a numerical analysis of geofeatures and allows the identification of sites with unique geodiversity in a study area. We applied this approach to geofeature data from three areas in Finland. Our results showed that patterns of geodiversity uniqueness varied profoundly among the three study areas and across sites within each area. This was due to different sets of geofeatures and distinct characteristics of each study area. More importantly, the approach presented here was robust across the datasets and selection criteria for sets of sites, showing potential for geoconservation in each study area. The geodiversity uniqueness approach is a promising starting point to identify and map sites with unique geodiversity that can be further verified using field observations. To improve our knowledge of geodiversity variation, complementary approaches providing objective information on contributions to total beta geodiversity are needed to advance geoconservation programmes across areas and different spatial scales.This article is part of the Theo Murphy meeting issue ‘Geodiversity science for society’.
Herbig Ae/Be Stars in nearby OB associations
Creators: name: Hernandez, Jesus
name: Calvet, Nuria
name: Hartmann, Lee
name: Briceno, Cesar
name: Sicilia-Aguilar, Aurora
name: Berlind, Perry
name: .
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have carried out a study of the early type stars in nearby OB associations spanning an age range of $\sim$ 3 to 16 Myr, with the aim of determining the fraction of stars which belong to the Herbig Ae/Be class. We studied the B, A, and F stars in the nearby ($\le 500$ pc) OB associations Upper Scorpius, Perseus OB2, Lacerta OB1, and Orion OB1, with membership determined from Hipparcos data. We obtained spectra for 440 Hipparcos stars in these associations, from which we determined accurate spectral types, visual extinctions, effective temperatures, luminosities and masses, using Hipparcos photometry. Using colors corrected for reddening, we find that the Herbig Ae/Be stars and the Classical Be stars (CBe) occupy clearly different regions in the JHK diagram. Thus, we use the location on the JHK diagram, as well as the presence of emission lines and of strong 12 microns flux relative to the visual to identify the Herbig Ae/Be stars in the associations. We find that the Herbig Ae/Be stars constitute a small fraction of the early type stellar population even in the younger associations. Comparing the data from associations with different ages and assuming that the near-infrared excess in the Herbig Ae/Be stars arises from optically thick dusty inner disks, we determined the evolution of the inner disk frequency with age. We find that the inner disk frequency in the age range 3 - 10 Myr in intermediate mass stars is lower than that in the low mass stars (< 1msun). This indicates that the time-scales for disk evolution are much shorter in the intermediate mass stars, which could be a consequence of more efficient mechanisms of inner disk dispersal (viscous evolution, dust growth and settling toward the midplane).
description: 34 pages, 10 figures
Engineering AlGaAs-on-insulator towards quantum optical applications
Creators: name: Placke, Marlon
name: Ramelow, Sven
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optics (physics.optics)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Aluminum gallium arsenide has highly desirable properties for integrated parametric optical interactions: large material nonlinearities, maturely established nanoscopic structuring through epitaxial growth and lithography, and a large band gap for broadband low-loss operation. However, its full potential for record-strength nonlinear interactions is only released when the semiconductor is embedded within a dielectric cladding to produce highly confining waveguides. From simulations of such, we present second and third order pair generation that could improve upon state-of-the-art quantum optical sources and make novel regimes of strong parametric photon-photon nonlinearities accessible.
description: 5 pages, 4 figures, resubmitted version
Donor Aid Cuts, Kenya Elections Affect Uganda Business Climate
Creators: name: Mawejje, Joseph
name: Mawejje, Joseph
Publisher: name: Unknown
Year: 2012
Subjects: subject: Agribusiness
subject: Agricultural Finance
subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Industrial Organization
subject: International Relations/Trade
subject: Labor and Human Capital
subject: Public Economics
subject: Economic activity
subject: eprc
subject: investment
subject: trade

description: In the October – December quarter of 2012, the business climate index declined to 4.5 points having recorded a score of 8 points in the previous (July – September) quarter. The deterioration of business environment perceptions emanated from elevated risks arising from the budget support withdrawals by some development partners and anxiety over potential business interruptions emanating from the presidential elections in neighbouring Kenya. Expectations for the next quarter are such that the business climate will start to improve but at a slower pace compared to the previous quarter. The drivers of the expected business climate improvement are anchored on the expected continuity in macroeconomic stability, recovery in domestic demand, and an upturn in the global economic outlook that is expected to boost export demand. On the overall, the business environment remains largely unchanged, having improved only modestly, and is expected to remain weak in the short term.
title: Dimensionally Regulated On-Shell Renormalisation In QCD And QED
Creators: name: Gray, Norman
Publisher: name: The Open University
Year: 1991

description: This thesis describes a technical advance in the treatment of massive fermion two-loop calculations in QED and QCD, which allows us to reduce complicated on-shell Feynman integrals to a large number of simple integrals, and one particularly complicated, but evaluable, one. The method extends the work of Chetyrkin and Tkachov to massive integrals, and is applicable to on-shell mass and wavefunction renormalisation.

 After an extensive review of the relevant areas of renormalisation, and of the rôle of quark masses in current algebra, we go on to use the extended technique to extract the fermion mass and wavefunction renormalisation constants to O(α2s), and to relate the running and pole masses to the bare mass and to each other. We find that the ratio of the running to the pole mass may be rather smaller than might be expected, which allows us to claim a perturbative source for a larger proportion of the strange quark constituent mass than has been usual before. In passing, we extract a number of two-loop renormalisation group coefficients, and find ourselves to be in agreement with other calculations.

 We also find that the on-shell fermion wavefunction renormalisation constant is quite unexpectedly gauge invariant to two loops, and that it is relatively simply related to the mass renormalisation constant. We suggest that this is the result of such intricate calculations that there must be a field-theoretic explanation waiting to be uncovered. We relate our results to the effective theory of a static quark.
Probing the Electronic Properties of Monolayer MoS$_2$ via Interaction with Molecular Hydrogen
Creators: name: Rezende, Natália P.
name: Cadore, Alisson R.
name: Gadelha, Andreij C.
name: Pereira, Cíntia L.
name: Ornelas, Vinicius
name: Watanabe, Kenji
name: Taniguchi, Takashi
name: Ferlauto, André S.
name: Malachias, Ângelo
name: Campos, Leonardo C.
name: Lacerda, Rodrigo G.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Applied Physics (physics.app-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: This work presents a detailed experimental investigation of the interaction between molecular hydrogen (H$_2$) and monolayer MoS$_2$ field effect transistors (MoS$_2$ FET), aiming for sensing application. The MoS$_2$ FET exhibits a response to H$_2$ that covers a broad range of concentration (0.1 - 90%) at a relatively low operating temperature range (300-473 K). Most important, H$_2$ sensors based on MoS$_2$ FETs show desirable properties such as full reversibility and absence of catalytic metal dopants (Pt or Pd). The experimental results indicate that the conductivity of MoS$_2$ monotonically increases as a function of the H$_2$ concentration due to a reversible charge transferring process. It is proposed that such process involves dissociative H$_2$ adsorption driven by interaction with sulfur vacancies in the MoS$_2$ surface (VS). This description is in agreement with related density functional theory studies about H$_2$ adsorption on MoS$_2$. Finally, measurements on partially defect-passivated MoS$_2$ FETs using atomic layer deposited aluminum oxide consist of an experimental indication that the VS plays an important role in the H$_2$ interaction with the MoS$_2$. These findings provide insights for futures applications in catalytic process between monolayer MoS$_2$ and H$_2$ and also introduce MoS$_2$ FETs as promising H$_2$ sensors.
Stability and gravitational collapse of neutron stars with realistic equations of state
Creators: name: Pretel, J. M. Z.
name: da Silva, M. F. A.
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We discuss the stability and construct dynamical configurations describing the gravitational collapse of unstable neutron stars with realistic equations of state compatible with the recent LIGO-Virgo constraints. Unlike other works that consider the collapse of a stellar configuration without a priori knowledge if it is stable or unstable, we first perform a complete analysis on stellar stability for such equations of state. Negative values of the squared frequency of the fundamental mode indicate us radial instability with respect to the collapse of the unstable star to a black hole. We find numerical solutions corresponding to the temporal and radial behavior during the evolution of the collapse for certain relevant physical quantities such as mass, luminosity, energy density, pressure, heat flow, temperature and quantities that describe bulk viscous processes. Our results show that the equation of state undergoes abrupt changes close to the moment of event horizon formation as a consequence of dissipative effects. During the collapse process all energy conditions are respected, which implies that our model is physically acceptable.
description: 13 pages, 11 figures
Phase Variation in the Pulse Profile of SMC X-1
Creators: name: Neilsen, J.
name: Hickox, R. C.
name: Vrtilek, S. D.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the results of timing and spectral analysis of X-ray high state observations of the high-mass X-ray pulsar SMC X-1 with Chandra, XMM-Newton, and ROSAT, taken between 1991 and 2001. The source has L_X ~ 3-5 x 10^38 ergs/s, and the spectra can be modeled as a power law plus blackbody with kT_BB \~ 0.18 keV and reprocessed emission radius R_BB ~ 2 x 10^8 cm, assuming a distance of 60 kpc to the source. Energy-resolved pulse profiles show several distinct forms, more than half of which include a second pulse in the soft profile, previously documented only in hard energies. We also detect significant variation in the phase shift between hard and soft pulses, as has recently been reported in Her X-1. We suggest an explanation for the observed characteristics of the soft pulses in terms of precession of the accretion disk.
description: 4 pages, 4 figures, accepted for publication in ApJL; v2 minor corrections, as will appear in ApJL
Plasmons and magnetoplasmons in partially bounded two-layer electron systems
Creators: name: Zabolotnykh, A. A.
name: Volkov, V. A.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We have analytically studied plasmons in an electron system comprised of two spatially separated layers -- an infinite two-dimensional electron system (2DES) and a 2D strip. Our analysis reveals the existence of plasmon modes that are localized near and propagate along the strip. These modes are characterized by the wave vector in the direction of the strip, as well as the number of charge density nodes, N, across the strip. In the long-wavelength limit, the fundamental mode N=0 is found to have gapless linear dispersion. When the external perpendicular magnetic field is applied, this mode remains gapless and exhibits peculiar magnetodispersion. We analyze the correlation between our findings and the previously established results on plasmons in gated and partially gated 2DESs.
description: 8 pages, 4 figures
KAAV INTERNATIONAL JOURNAL full.pdf
Creators: name: Raj, Nitesh
Publisher: name: figshare
Year: 2020
Subjects: Economics

description: This paper aims at identifying and specifying the significance of Rashtriya Uchhtar Shiksha Abhiyan(RUSA) in Jharkhand. Statistical analysis of historical and current data has done in respect to thelevel of higher education in Jharkhand. Considering that, access, equity and excellence are thebackbone of educational reforms supported by teacher bodies have to be parallel remedied bygovernments. The bodies also have to pragmatically approach this reform scheme and providecollective wisdom for further quality refinement. Resistance to change is born out of inadequateunderstanding. The concern is whether we want higher education manpower to acquireinternational-level expertise with high employability or dwindle in mediocrity? While RUSA is not adirect response to the rankings of economic growth rate, it does aim to “attain higher levels ofaccess, equity and excellence in the State higher education system with greater efficiency,transparency, accountability and responsiveness”. Hence, RUSA is an excellent opportunity to theState Universities to upgrade educational and research ambience of infrastructure, knowledgeresources and skill development expertise to produce international quality manpower.
3-D Photoionization Structure and Distances of Planetary Nebulae II. Menzel 1
Creators: name: Monteiro, Hektor
name: Schwarz, Hugo E.
name: Gruenwald, Ruth
name: Guenthner, Katherine
name: Heathcote, Steve R.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We present the results of a spatio-kinematic study of the planetary nebula Menzel 1 using spectro-photometric mapping and a 3-D photoionization code. We create several 2-D emission line images from our long-slit spectra, and use these to derive the line fluxes for 15 lines, the Halpha/Hbeta extinction map, and the [SII] line ratio density map of the nebula. We use our photoionization code constrained by these data to derive the three-dimensional nebular structure and ionizing star parameters of Menzel 1 by simultaneously fitting the integrated line intensities, the density map, and the observed morphologies in several lines, as well as the velocity structure. Using theoretical evolutionary tracks of intermediate and low mass stars, we derive a mass for the central star of 0.63+-0.05 Msolar. We also derive a distance of 1050+_150 pc to Menzel 1.
description: To be published in ApJ of 10th February 2005. 12 figures
Full text Uranium industry in east singhbhum_ A case study in socio-economic perspective.pdf1.pdf
Creators: name: Raj, Nitesh
Publisher: name: figshare
Year: 2020
Subjects: Economics

description: The research study is based upon the Socio-economic evaluation of Uranium Industry in Jadugoda thatis in East Singhbhum of State of Jharkhand (India), the main occupation of their inhabitants wascultivation, and Artisans tribes like, mahali, karmali and lohra were prevailing an important role at thatplace. After establishment of Uranium industry in Jharkhand the Socio-economic condition of people ofEast Singhbhum has been improved or not is an important question and concern, whether the people ofthat area are still in position to settle their life in a good manner or the industry has worsen their life.The health and social condition have been worsened but economic and employment conditions havebeen improved in that area.
La tarification de l'électricité: un sujet négligé lors des débats sur la nationalisation en 1962
Creators: name: Bernard, Jean-Thomas
name: Bernard, Jean-Thomas
Publisher: name: Unknown
Year: 2014
Subjects: subject: Environmental Economics and Policy
subject: Nationalisation
subject: tarification
subject: électricité
subject: Hydro-Québec

description: Après les débats enflammés des années trente, la tarification de l’électricité a occupé peu de place dans ceux portant sur la nationalisation de l’électricité en 1962. La raison principale de cette absence est que le cadre réglementaire élaboré lors de la création de la Commission hydroélectrique de Québec en 1944 fut adopté sans modification significative lors de cette deuxième nationalisation. Le principe de la tarification de l’électricité selon le coût moyen ne fut pas remis en question. Outre le rapatriement de l’impôt sur le revenu des corporations payé au gouvernement fédéral, deux objectifs explicitement poursuivis lors de la nationalisation en 1962 ont laissé une influence durable sur la tarification de l’électricité, à savoir, l’uniformisation des tarifs pour l’ensemble du territoire et l’usage des tarifs pour fins de promotion industrielle. Après 1963, le gouvernement a imposé des nouvelles charges fiscales à Hydro-Québec sans remettre en cause la tarification selon le coût moyen.