cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Locks and Dam 26: Critique of Corps' Forecasts and Capacity Analysis
Creators: name: Carroll, Joseph L.
name: Rao, Srikanth
name: Carroll, Joseph L.
name: Rao, Srikanth
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Self-Elicitation of Requirements with Automated GUI Prototyping
Creators: name: Kolthoff, Kristian
name: Bartelt, Christian
name: Ponzetto, Simone Paolo
name: Schneider, Kurt
Publisher: name: arXiv
Year: 2024
Subjects: subject: Software Engineering (cs.SE)
subject: FOS: Computer and information sciences

description: Requirements Elicitation (RE) is a crucial activity especially in the early stages of software development. GUI prototyping has widely been adopted as one of the most effective RE techniques for user-facing software systems. However, GUI prototyping requires (i) the availability of experienced requirements analysts, (ii) typically necessitates conducting multiple joint sessions with customers and (iii) creates considerable manual effort. In this work, we propose SERGUI, a novel approach enabling the Self-Elicitation of Requirements (SER) based on an automated GUI prototyping assistant. SERGUI exploits the vast prototyping knowledge embodied in a large-scale GUI repository through Natural Language Requirements (NLR) based GUI retrieval and facilitates fast feedback through GUI prototypes. The GUI retrieval approach is closely integrated with a Large Language Model (LLM) driving the prompting-based recommendation of GUI features for the current GUI prototyping context and thus stimulating the elicitation of additional requirements. We envision SERGUI to be employed in the initial RE phase, creating an initial GUI prototype specification to be used by the analyst as a means for communicating the requirements. To measure the effectiveness of our approach, we conducted a preliminary evaluation. Video presentation of SERGUI at: https://youtu.be/pzAAB9Uht80
Determination of Polarized PDFs from a QCD Analysis of Inclusive and Semi-inclusive Deep Inelastic Scattering Data
Creators: name: Leader, Elliot
name: Sidorov, Aleksander V.
name: Stamenov, Dimiter B.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A new combined next to leading order QCD analysis of the polarized inclusive and semi-inclusive deep inelastic lepton-hadron scattering (DIS) data is presented. In contrast to previous combined analyses, the $1/Q^2$ terms (kinematic - target mass corrections, and dynamic - higher twist corrections) in the expression for the nucleon spin structure function $g_1$ are taken into account. The new COMPASS data are included in the analysis. The impact of the semi-inclusive data on the polarized parton densities (PDFs) and on the higher twist corrections is discussed. The new results for the PDFs are compared to our (Leader, Sidorov, Stamenov) LSS'06 PDFs, obtained from the fit to the inclusive DIS data alone, and to those obtained from the de Florian, Sassot, Stratmann, and Vogelsang global analysis.
description: 11 pages, 8 figures, a version to be published in Phys. Rev. D
Cost and Service Characteristics of Small Community Transit Operations
Creators: name: Kendall, Donald
name: Misner, Joseph
name: Waksman, Robert
name: Kendall, Donald
name: Misner, Joseph
name: Waksman, Robert
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Cost of Alternative Systems to Serve Elderly and Handicapped in Small Urban Areas
Creators: name: Kidder, Alice E.
name: Sen, Lalita
name: Amedee, George
name: McKelvey, Douglas
name: Kidder, Alice E.
name: Sen, Lalita
name: Amedee, George
name: McKelvey, Douglas
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Simplified Procedures for Long-Range Transportation Planning in Small Urban Areas
Creators: name: Chatterjee, Arun
name: Wegmann, Frederick J.
name: Grecco, William L
name: Chatterjee, Arun
name: Wegmann, Frederick J.
name: Grecco, William L
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Structural brain mediators of the relation between exposures and adolescent cognitive ability
Creators: name: Nayak, Prakriti
name: Kercova, Klaidia
name: Ritchie, Stuart
Publisher: name: Open Science Framework
Year: 2022

description: Master's dissertation projects to check whether the cerebellum and PFC volume mediate the correlation, if any, between exposures (sports and socioeconomic status) and cognitive ability in adolescents, using data from the ABCD study.
Shippers' Perceptions and Preferences for Motor Carrier Performance in Urban Areas: Implications for Consolidation Programs
Creators: name: Robicheaux, Robert A.
name: Cadotte, Ernest R.
name: Robicheaux, Robert A.
name: Cadotte, Ernest R.
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Status of regional climate and ecosystems observing Report
Creators: name: Speich, Sabrina
name: Karstensen, Johannes
name: McDonagh, Elaine
Publisher: name: AtlantOS
Year: 2019

description: Report on the current observing status in the North Atlantic subpolar gyre and the South Atlantic subtropical gyre, containing the results of the investigation on regional observing activities, systems, and connectivity in relation to climate and ecosystems
TOPONYMIC CLASSIFICATIONS
Creators: name: Ismatova, Nodirakhon
name: Mehmonova, Ruxshona
name: Abdunazarova, Diyora
Publisher: name: Zenodo
Year: 2023

description: Toponymy can be studied geographically as well as linguistically according to it features of geographical and linguistical. The article illustrates on the principles of toponyms as well as it includes some methods of descriptive and semantic analysis of toponyms. Moreover, it is given various types of toponyms and features of them.
Stability analysis of f(R)-AdS black holes
Creators: name: Moon, Taeyoon
name: Myung, Yun Soo
name: Son, Edwin J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the stability of f(R)-AdS (Schwarzschild-AdS) black hole obtained from f(R) gravity. In order to resolve the difficulty of solving fourth order linearized equations, we transform f(R) gravity into the scalar-tensor theory by introducing two auxiliary scalars. In this case, the linearized curvature scalar becomes a dynamical scalaron, showing that all linearized equations are second order. Using the positivity of gravitational potentials and S-deformed technique allows us to guarantee the stability of f(R)-AdS black hole if the scalaron mass squared satisfies the Breitenlohner-Freedman bound. This is confirmed by computing quasinormal frequencies of the scalaron for large f(R)-AdS black hole.
description: 17 pages, 1 figure, version to appear in EPJC
The Impact of Commuter Air Carrier Certification
Creators: name: Dajani, Jarir S.
name: Hawk, Philip J.
name: Dajani, Jarir S.
name: Hawk, Philip J.
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Advocating for science through non-profits
Creators: name: Bankston, Adriana
Publisher: name: F1000 Research Limited
Year: 2019

description: This workshop was given at the UC Riverside F.A.R.E. (Fellowships, Advising, Running for Office, and Engagement) Day on April 19, 2019. It discussed policy and advocacy work from the Future of Research (with postdoctoral salaries as an example) and JSPG as a vehicle for students and young scholars to publish policy pieces, and included an interactive section on learning how to advocate for a particular cause.
Color Fields on the Light-Shell
Creators: name: Georgi, Howard
name: Kestin, Greg
name: Sajjad, Aqil
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the classical color radiation from very high energy collisions that produce colored particles. In the extreme high energy limit, the classical color fields are confined to a light-shell expanding at $c$ and are associated with a non-linear $σ$-model on the 2D light-shell with specific symmetry breaking terms. We argue that the quantum version of this picture exhibits asymptotic freedom and may be a useful starting point for an effective light-shell theory of the structure between the jets at a very high energy collider.
description: 11 pages, no figures
Global fits of the Minimal Universal Extra Dimensions scenario
Creators: name: Bertone, Gianfranco
name: Kong, Kyoungchul
name: de Austri, Roberto Ruiz
name: Trotta, Roberto
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In theories with Universal Extra-Dimensions (UED), the gamma_1 particle, first excited state of the hypercharge gauge boson, provides an excellent Dark Matter (DM) candidate. Here we use a modified version of the SuperBayeS code to perform a Bayesian analysis of the minimal UED scenario, in order to assess its detectability at accelerators and with DM experiments. We derive in particular the most probable range of mass and scattering cross sections off nucleons, keeping into account cosmological and electroweak precision constraints. The consequences for the detectability of the gamma_1 with direct and indirect experiments are dramatic. The spin-independent cross section probability distribution peaks at ~ 10^{-11} pb, i.e. below the sensitivity of ton-scale experiments. The spin-dependent cross-section drives the predicted neutrino flux from the center of the Sun below the reach of present and upcoming experiments. The only strategy that remains open appears to be direct detection with ton-scale experiments sensitive to spin-dependent cross-sections. On the other hand, the LHC with 1 1/fb of data should be able to probe the current best-fit UED parameters.
description: 15 pages, 11 figures; minor quantitative differences wrt v1 due to the correction of a numerical problem, main results unchanged
Particle number conservation in quantum many-body simulations with matrix product operators
Creators: name: Muth, Dominik
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Physics (quant-ph)
subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Incorporating conservation laws explicitly into matrix product states (MPS) has proven to make numerical simulations of quantum many-body systems much less resources consuming. We will discuss here, to what extent this concept can be used in simulation where the dynamically evolving entities are matrix product operators (MPO). Quite counter-intuitively the expectation of gaining in speed by sacrificing information about all but a single symmetry sector is not in all cases fulfilled. It turns out that in this case often the entanglement imposed by the global constraint of fixed particle number is the limiting factor.
description: minor changes, 18 pages, 5 figures
Linguistic synchrony : indicator or facilitator of therapeutic bond
Creators: name: Colton, Tayler M. S.
Publisher: name: University of British Columbia
Year: 2022

description: Interpersonal synchrony is an adaptive and pro-social process that has been associated with social bonding, cohesion, and cooperation. Existing research in a therapeutic context has primarily conceptualized linguistic synchrony as an indication of the therapeutic relationship. However, in non-therapeutic contexts, synchrony has been conceptualized as a process that facilities relationship formation and maintenance. The aim of the present study was to examine if an indication model or facilitation model provided a better explanation for the association between linguistic synchrony and the therapeutic bond. Online text-based crisis sessions (N = 350) with clients in suicidal crisis were coded for linguistic synchrony (i.e., similarity of function words) and therapeutic bond. To examine the indication and facilitation models, we used Random Intercept Cross-Lagged Panel Models (RI-CLPM; Hamaker et al., 2015) and compared the model fit of the competing models. The association between linguistic synchrony and therapeutic bond was better explained by the facilitation model (i.e., linguistic synchrony predicting the therapeutic bond) than the indication model (i.e., linguistic synchrony and therapeutic bond occurring simultaneously). However, a combined model that included (a) linguistic synchrony predicting therapeutic bond and (b) the cross-sectional association between therapeutic bond and linguistic synchrony was the best fit to our data. This study contributes theoretical understanding of the association between linguistic synchrony and therapeutic bond. Clinical implications for counsellor practice are discussed.
The 7th Decade Manager
Creators: name: Frobisher, Graham
Publisher: name: University of Leicester
Year: 2023
Subjects: Uncategorized

description: Existing gerontological literature tends to concentrate on older workers, using a broad cohort age range, and conflates the manager with non-manager. This risks overlooking critical matters that affect managers who are in their 7th decade (7DM). This thesis explores changes attributed to ageing and the work environment and includes aspects of personal life. An interpretative methodology was used to explore the experiences of 32 managers from 29 organisations in 10 different sectors. The constructs of age and work were used to frame the study with identity envisaged as a bridging concept between them. The analysis shows the 7DM is experiencing change. Age is used dichotomously by the 7DM, identifying as subjectively younger yet openly acknowledging and accepting signs and symptoms of ageing. Temperamentally, the 7DM appeared more tolerant and kinder, yet can be impatient and outspoken. Work remains important, providing structure, sense of purpose and socialisation, however career progression is not. The 7DM exercises generativity to create a work-based legacy, and acts as a wise and trusted confidant who is sought out for guidance and counsel in work and personal matters. The findings add to knowledge about the older manager by providing insight into the role of identity during periods of change. The research shows that identity features prominently for the 7DM, embedded and interwoven in all aspects of the constructs of age and work. The 7DM’s authenticity is informed by their age and identity, invoking experience, trust and integrity in all aspects of life. Identity work was used to try and reconcile conflicting positions, such as the liminality associated with impending cessation of work and the transition to non-work.
Wu Han rehabilitiert
Creators: name: Staiger, Brunhild
Publisher: name: China aktuell
Year: 2023

description: Wu Han, bekannter Spezialist für Ming-Geschichte und 1952 bis 1966 stellvertretender Bürgermeister von Peking, gehörte 1966 zu den ersten prominenten Opfern der Kulturrevolution. Die Kritik an seinem historischen Drama "Hai Rui wird entlassen" bildete das unmittelbare Vorspiel zur Kulturrevolution. Seit seiner Verhaftung im Jahre 1966 war über sein weiteres Schicksal offiziell nichts mehr zu erfahren; westliche China-Wissenschaftler, die sich bei Besuchen in China immer wieder nach Wu Han erkundigten, erhielten auf ihre Fragen keine Antworten, wenngleich man vermuten musste, dass Wu Han nicht mehr am Leben sei. Anfang Januar 1979 erst teilte die "Volkszeitung" mit, dass Wu Han "bis in den Tod grausam verfolgt" worden sei. Es dauerte über zwei Jahre seit dem Sturz der Vier, bis über Wu Han und sein berühmtes Drama über Hai Rui wieder offiziell gesprochen werden konnte. Zu einer offiziellen Würdigung, etwa durch eine postume Trauerfeier, wie sie anderen prominenten Opfern der Kulturrevolution zuteil wurde, ist es bisher allerdings noch nicht gekommen. Wu Hans Name steht bisher eher im Schatten der jüngsten großen Rehabilitierungen. Im folgenden sollen nach einer kurzen Biographie Wu Hans die Umstände seiner Rehabilitierung sowie die Hintergründe und Auswirkungen der Kritik an Wu Han aus heutiger chinesischer Sicht dargestellt werden. Daran schließen sich einige Reflexionen über die Rehabilitierung an.
description: China aktuell, China aktuell - Januar 1979
Money-Back Rates: A Case Study in Regulatory Myopia
Creators: name: Levine, Harvey A.
name: O'Connor, Thomas M.
name: Shaw, Charles E.
name: Levine, Harvey A.
name: O'Connor, Thomas M.
name: Shaw, Charles E.
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
ATLAS pull-up banners for public engagement
Creators: name: Paterson, Emma
Publisher: name: Zenodo
Year: 2019
Subjects: public engagement

description: 6 pull-up banners designed to explain the ATLAS project to the general public. Banners are designed to fit 800 mm x 2000 mm template. Please contact eu-atlas@ed.ac.uk if you would like access to the original files.

ATLAS Overview banner

Case Studies banner

Creature Close Ups banner

How Deep banner

Ocean Literacy banner

Exploring With Technology banner
The clustering of massive galaxies at z~0.5 from the first semester of BOSS data
Creators: name: White, Martin
name: Blanton, M.
name: Bolton, A.
name: Schlegel, D.
name: Tinker, J.
name: Berlind, A.
name: da Costa, L.
name: Kazin, E.
name: Lin, Y. -T.
name: Maia, M.
name: McBride, C.
name: Padmanabhan, N.
name: Parejko, J.
name: Percival, W.
name: Prada, F.
name: Ramos, B.
name: Sheldon, E.
name: de Simoni, F.
name: Skibba, R.
name: Thomas, D.
name: Wake, D.
name: Zehavi, I.
name: Zheng, Z.
name: Nichol, R.
name: Schneider, D.
name: Strauss, Michael A.
name: Weaver, B. A.
name: Weinberg, David H.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We calculate the real- and redshift-space clustering of massive galaxies at z~0.5 using the first semester of data by the Baryon Oscillation Spectroscopic Survey (BOSS). We study the correlation functions of a sample of 44,000 massive galaxies in the redshift range 0.4
description: 11 pages, 12 figures, matches version accepted by ApJ
Galaxy formation in semi-analytic models and cosmological hydrodynamic zoom simulations
Creators: name: Hirschmann, M.
name: Naab, T.
name: Somerville, R.
name: Burkert, A.
name: Oser, L.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present a detailed comparison between numerical cosmological hydrodynamic zoom simulations and semi-analytic models (SAMs) run within merger trees extracted from the simulations. The high-resolution simulations represent 48 individual halos with virial masses in the range 2.4*10^11M_sun < M_Halo < 3.3*10^13M_sun. They include radiative H & He cooling, photo-ionization, star formation and thermal SN feedback. We compare with different SAM versions including only this complement of physical processes, and also ones including supernova driven winds, metal cooling, and feedback from AGN. Our analysis is focused on the cosmic evolution of the baryon content in galaxies and its division into various components (stars, cold gas, and hot gas). Both the SAMs and simulations are compared with observational relations between halo mass and stellar mass, and between stellar mass and star formation rate, at low and high redshift. The simulations turn out to have much higher star formation efficiencies (by about a factor of ten) than the SAMs. Therefore the cold gas is consumed much more rapidly in the simulations and stars form much earlier. Also, simulations show a transition between stellar mass growth that is dominated by in situ formation of stars to growth that is predominantly through accretion of stars formed in external galaxies. In SAMs, stellar growth is always dominated by in situ star formation. In addition, SAMs overpredict the overall gas accretion rates relative to the simulations, and overestimate the fraction of "hot" relative to "cold" accretion. We discuss the reasons for these discrepancies, and identify several physical processes that are missing in our SAM. We also highlight physical processes that are neglected in the simulations studied here, but which appear to be crucial in order to understand the properties of real galaxies.
description: 25 pages, 17 figures, accepted for publication by MNRAS
Acoustic phonons and spin relaxation in graphene nanoribbons
Creators: name: Droth, Matthias
name: Burkard, Guido
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Phonons are responsible for limiting both the electron mobility and the spin relaxation time in solids and provide a mechanism for thermal transport. In view of a possible transistor function as well as spintronics applications in graphene nanoribbons, we present a theoretical study of acoustic phonons in these nanostructures. Using a two-dimensional continuum model which takes into account the monatomic thickness of graphene, we derive Hermitian wave equations and infer phonon creation and annihilation operators. We elaborate on two types of boundary configuration, which we believe can be realized in experiment: (i) fixed and (ii) free boundaries. The former leads to a gapped phonon dispersion relation, which is beneficial for high electron mobilites and long spin lifetimes. The latter exhibits an ungapped dispersion and a finite sound velocity of out-of-plane modes at the center of the Brillouin zone. In the limit of negligible boundary effects, bulk-like behavior is restored. We also discuss the deformation potential, which in some cases gives the dominant contribution to the spin relaxation rate T_1^{-1}.
description: 7 pages, 4 figures
Молекулярные механизмы нейропротективного эффекта краниоцеребральной гипотермии у новорожденных
Creators: name: Koshurba, Illia
Publisher: name: Zenodo
Year: 2022

description: Кошурба И.В. Молекулярные механизмы нейропротективного эффекта краниоцеребральной гипотермии у новорожденных. Сборник материалов итоговой научно-практической конференции "Актуальные проблемы медицины" (27 января 2022 г.).: тезисы доклада. Гродно. 2022. С. 415–416. DOI: https://doi.org/10.5281/zenodo.7924999.
Beliefs About Buses, Carpools, and Single Occupant Autos: A Market Segmentation Approach
Creators: name: Dobson, Ricardo
name: Tischer, Mary Lynn
name: Dobson, Ricardo
name: Tischer, Mary Lynn
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Reverse Engineering Approach to Quantum Electrodynamics
Creators: name: Smilga, Walter
Publisher: name: arXiv
Year: 2010
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: The S matrix of e--e scattering has the structure of a projection operator that projects incoming separable product states onto entangled two-electron states. In this projection operator the empirical value of the fine-structure constant alpha acts as a normalization factor. When the structure of the two-particle state space is known, a theoretical value of the normalization factor can be calculated. For an irreducible two-particle representation of the Poincare group, the calculated normalization factor matches Wyler's semi-empirical formula for the fine-structure constant alpha. The empirical value of alpha, therefore, provides experimental evidence that the state space of two interacting electrons belongs to an irreducible two-particle representation of the Poincare group.
description: 12 pages, minor changes
Development of efficient methods for the syntheses of fluorinated motifs using fluorinated gases
Creators: name: Lee, Chia Wei
Publisher: name: University of British Columbia
Year: 2022

description: Sulfonyl fluorides, alkyl fluorides and acyl fluorides are common functional groups found in numerous industrial products, including in pharmaceuticals, agrochemicals, and functionalized materials. In spite of numerous methods developed, there are still many limitations in the existing protocols to access these fluorinated motifs. This thesis describes my contribution to the development of new synthetic methods to access sulfonyl fluorides, alkyl fluorides, and acyl fluorides using two fluorinated gases, sulfuryl fluoride and thionyl fluoride. Chapter 1 gives a broad introduction to applications of fluorochemicals in pharmaceutical, polymer, and agrochemical industries, which contribute significantly to market share and revenue. Syntheses of fluorochemicals are of great interest in synthetic chemistry using various fluorinating reagents. This chapter details the development and transformations of two gaseous fluorinating reagents, sulfuryl fluoride and thionyl fluoride. Chapter 2 details the development of a novel fluorosulfurylation of Grignard reagents using sulfuryl fluoride. The reaction converts a wide range of alkyl, aryl, and heteroaryl Grignard reagents into the corresponding sulfonyl fluorides in 18-78% yields. A unique advantage of this method over previously reported fluorosulfurylation reactions is that the generated sulfonyl fluorides can be used to access unsymmetrical diaryl sulfones, sulfonate esters, and sulfonamides in a one-pot process. The development of an efficient deoxyfluorination of alcohols using sulfuryl fluoride to synthesize alkyl fluorides is reported in chapter 3. The broad scope including primary and secondary aliphatic alcohols in 46-92% yields demonstrated a good functional group tolerance and net inversion of configuration. A gram-scale synthesis proved the potential synthetic relevance of this methodology. Chapter 4 describes the development of ex situ generation of thionyl fluoride and subsequent demonstration of its use to access amino acid fluorides in 86-98% yields under mild conditions and short reaction time. The method is applicable for sequential reaction, whereby the generated amino acid fluorides can be converted to the corresponding dipeptides in a one-pot, column-free process with retention of optical purity. The broad scope allows for natural and unnatural amino acid substrates with a wide array of protecting groups. The new approach was applied to the sequential liquid phase peptide synthesis and solid phase peptide synthesis.
Structural insights into DNA lagging strand replication and translesion synthesis
Creators: name: Lancey, Claudia
Publisher: name: University of Leicester
Year: 2023
Subjects: Uncategorized

description: DNA replication requires the coordination of many different enzymes at the primer terminus. The eukaryotic sliding clamp, proliferating cell nuclear antigen (PCNA), encircles DNA at primer-template junctions, providing a platform for DNA polymerases and other enzymes to bind and increasing their processivity and activity on DNA. Many DNA processing enzymes contain a conserved PIP-box motif, which binds a hydrophobic pocket on PCNA. This thesis focuses on two processes: Okazaki fragment maturation and translesion synthesis (TLS). In the former, the lagging strand polymerase (Pol) δ synthesises each Okazaki fragment upstream of the last, displacing a portion of the downstream fragment. Flap endonuclease (FEN1) cleaves the resulting flap, and a ligase enzyme seals the nick. In TLS, Pol δ stalls opposite a DNA lesion. It must then be replaced by a TLS polymerase, which can bypass the lesion, before resuming synthesis downstream. Both processes involve sequential action of enzymes. As PCNA is a homotrimer with three PIP-box binding pockets, it may recruit more than one of these enzymes simultaneously for a fast and efficient changeover. This simultaneous binding, the “toolbelt” model, has been demonstrated experimentally in archaea and bacteria. Evidence of PCNA toolbelts in eukaryotes has proven more elusive, and this thesis set out to explore the notion further. Using single-particle cryo-electron microscopy, the work presented here has uncovered structural data of different polymerases forming holoenzymes with PCNA and primer-template DNA. This work shows that Pol δ binds PCNA at the side, leaving room for a second binding partner – and indeed we show structural evidence that FEN1 can bind PCNA simultaneously, forming a toolbelt. TLS Pol κ also binds towards one side of PCNA, inviting the hypothesis of a TLS toolbelt. Together, this work provides an insight into how the interactions of enzymes with PCNA facilitates enzyme switching at the primer terminus.
A Time-Series Analysis of the Impact of Mass Competition on Commuter Rail Ridership
Creators: name: Johnson, Chris
name: Burrows, Benjamin
name: Heramb, Cherilyn
name: Kunze, Robert C.
name: Sen, Ashish K.
name: Johnson, Chris
name: Burrows, Benjamin
name: Heramb, Cherilyn
name: Kunze, Robert C.
name: Sen, Ashish K.
Publisher: name: Unknown
Year: 1976
Subjects: Public Economics

description: Presented at the 17th Transportation Research Forum meeting, Oct. 29-30,1976, Boston, MA
Investigating early land plant cuticular waxes using physocomitrella patens as a model species
Creators: name: Kurschner, Lewis Miles
Publisher: name: University of British Columbia
Year: 2022

description: Cuticular wax research in Arabidopsis thaliana and other important model plant species has led to the elucidation of biochemical pathways for aliphatic wax synthesis in flowering plants, however, we still lack a critical understanding of how these important pathways developed in early land plants. Physcomitrella patens is a model moss species that is used in laboratory research and is believed to live in habitats similar to those found roughly 500 million years ago. Thus, the cuticle present in Physcomitrella can be used to explore the nature of the cuticles from early land plants. The goal of this thesis was to assess whether the proteins involved in production of wax components for the Physcomitrella cuticle are similar to those that produce the well-studied Arabidopsis cuticle. Six hypothesized cuticular wax genes were discovered in Physcomitrella based on sequence similarity to homologs known to be involved in wax biosynthesis in Arabidopsis. PpCERA, PpCERB, PpCERC, and PpCERD were discovered to have close sequence similarity to AtCER1 and AtCER3, while PpFAR1 and PpFAR2 displayed sequence similarity to AtCER4. Knock-out mutants were generated for each of the Physcomitrella candidate genes, except for Ppfar1, and the ensuing cuticular waxes were analyzed via gas chromatography-flame ionization detection (GC-FID) and gas chromatography-mass spectroscopy (GC-MS). A complementation experiment with Physcomitrella genes in knock-out mutants of the homologs in Arabidopsis was performed to determine if the moss genes could complement the wax-deficient phenotype. The Physcomitrella genes were also expressed in yeast to investigate their biological function, but these studies were discontinued due to technical difficulties. Physcomitrella mutants demonstrated that PpFAR2 participates in the production of primary alcohols and functions in the primary alcohol pathway. PpCERA, PpCERB, PpCERC, and PpCERD participate in the production aldehydes and alkanes. When PpCERC and PpCERD were expressed Arabidopsis alkane pathway mutants, Atcer1-4 and Atcer3-6, the wax deficient phenotype was complemented, and alkane pathway functionality was restored. Expression of PpCERC and PpCERD in Atcer4-3 failed to restore the primary alcohol pathway, suggesting that these enzymes may function in the alkane, not primary alcohol, pathway in Physcomitrella.
Is the Universe homogeneous?
Creators: name: Maartens, Roy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The standard model of cosmology is based on the existence of homogeneous surfaces as the background arena for structure formation. Homogeneity underpins both general relativistic and modified gravity models and is central to the way in which we interpret observations of the CMB and the galaxy distribution. However, homogeneity cannot be directly observed in the galaxy distribution or CMB, even with perfect observations, since we observe on the past lightcone and not on spatial surfaces. We can directly observe and test for isotropy, but to link this to homogeneity, we need to assume the Copernican Principle. First, we discuss the link between isotropic observations on the past lightcone and isotropic spacetime geometry: what observations do we need to be isotropic in order to deduce spacetime isotropy? Second, we discuss what we can say with the Copernican assumption. The most powerful result is based on the CMB: the vanishing of the dipole, quadrupole and octupole of the CMB is sufficient to impose homogeneity. Real observations lead to near-isotropy on large scales - does this lead to near-homogeneity? There are important partial results, and we discuss why this remains a difficult open question. Thus we are currently unable to prove homogeneity of the Universe on large-scales, even with the Copernican Principle. However we can use observations of the CMB, galaxies and clusters to test homogeneity itself.
description: Based on an invited talk at a Theo Murphy Meeting "Testing general relativity with cosmology". Minor corrections, references updated. To appear Phil. Trans. R. Soc. A
Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches
Creators: name: Wharton, S. B.
name: Wang, D.
name: Parikh, C.
name: Matthews, F. E.
name: Brayne, C.
name: Ince, P. G.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Research

description: Abstract: Aβ-amyloid deposition is a key feature of Alzheimer’s disease, but Consortium to Establish a Registry for Alzheimer's Disease (CERAD) assessment, based on neuritic plaque density, shows a limited relationships to dementia. Thal phase is based on a neuroanatomical hierarchy of Aβ-deposition, and in combination with Braak neurofibrillary tangle staging also allows derivation of primary age-related tauopathy (PART). We sought to determine whether Thal Aβ phase predicts dementia better than CERAD in a population-representative cohort (n = 186) derived from the Cognitive Function and Ageing Study (CFAS). Cerebral amyloid angiopathy (CAA) was quantitied as the number of neuroanatomical areas involved and cases meeting criteria for PART were defined to determine if they are a distinct pathological group within the ageing population. Agreement with the Thal scheme was excellent. In univariate analysis Thal phase performed less well as a predictor of dementia than CERAD, Braak or CAA. Logistic regression, decision tree and linear discriminant analysis were performed for multivariable analysis, with similar results. Thal phase did not provide a better explanation of dementia than CERAD, and there was no additional benefit to including more than one assessment of Aβ in the model. Number of areas involved by CAA was highly correlated with assessment based on a severity score (p < 0.001). The presence of capillary involvement (CAA type I) was associated with higher Thal phase and Braak stage (p < 0.001). CAA was not associated with microinfarcts (p = 0.1). Cases satisfying pathological criteria for PART were present at a frequency of 10.2% but were not older and did not have a higher likelihood of dementia than a comparison group of individuals with similar Braak stage but with more Aβ. They also did not have higher hippocampal-tau stage, although PART was weakly associated with increased presence of thorn-shaped astrocytes (p = 0.048), suggesting common age-related mechanisms. Thal phase is highly applicable in a population-representative setting and allows definition of pathological subgroups, such as PART. Thal phase, plaque density, and extent and type of CAA measure different aspects of Aβ pathology, but addition of more than one Aβ measure does not improve dementia prediction, probably because these variables are highly correlated. Machine learning predictions reveal the importance of combining neuropathological measurements for the assessment of dementia.
Forward Analysis and Model Checking for Trace Bounded WSTS
Creators: name: Chambart, Pierre
name: Finkel, Alain
name: Schmitz, Sylvain
Publisher: name: arXiv
Year: 2010
Subjects: subject: Logic in Computer Science (cs.LO)
subject: FOS: Computer and information sciences
subject: D.2.4; F.4.1; F.4.3

description: We investigate a subclass of well-structured transition systems (WSTS), the bounded---in the sense of Ginsburg and Spanier (Trans. AMS 1964)---complete deterministic ones, which we claim provide an adequate basis for the study of forward analyses as developed by Finkel and Goubault-Larrecq (Logic. Meth. Comput. Sci. 2012). Indeed, we prove that, unlike other conditions considered previously for the termination of forward analysis, boundedness is decidable. Boundedness turns out to be a valuable restriction for WSTS verification, as we show that it further allows to decide all $ω$-regular properties on the set of infinite traces of the system.
High-temperature magnetic properties of noninteracting single-domain Fe3O4 nanoparticles
Creators: name: Wang, Jun
name: Beeli, Pieder
name: Meng, L. H.
name: Zhao, Guo-meng
Publisher: name: arXiv
Year: 2010
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Magnetic measurements have been performed on 40-nm sphere-like Fe3O4 nanoparticles using a Quantum Design vibrating sample magnetometer. Coating Fe3O4 nanoparticles with SiO2 effectively eliminates magnetic interparticle interactions so that the coercive field HC in the hightemperature range between 300 K and the Curie temperature (855 K) can be well fitted by an expression for noninteracting randomly oriented single-domain particles. From the fitting parameters, the effective anisotropy constant K is found to be (1.68 \pm 0.17) \times 105 erg/cm3, which is slightly larger than the bulk magnetocrystalline anisotropy constant of 1.35 \times 105 erg/cm3. Moreover, the inferred mean particle diameter from the fitting parameters is in quantitative agreement with that determined from transmission electron microscope. Such a quantitative agreement between data and theory suggests that the assemble of our SiO2-coated sphere-like Fe3O4 nanopartles represents a good system of noninteracting randomly-oriented single-domain particles.
description: 9 pages, 5 figures
Monitoring reports of pilot cases
Creators: name: BONO, Lorenzo
name: ANDREAZZOLI, Laura
name: BILLON, Yoann
name: Busch Thomsen Birte
name: CARVALHO, Rute
name: CLAVIJO, Alberto
name: ERIKSSON, Mattias
name: GIOURKA, Paraskevi
name: GOLLNOW, Sebastian
name: LENTUCCI, Lorella
name: LÓPEZ-MURCIA, Javier
name: GILSANZ, Celia
name: GONZALEZ, Gerardo
name: MOLOWNY, Alejandro
name: KAYADJANIAN, Maxime
name: Nascimento, Gisela
name: OBERSTEINER, Gudrun
name: POZNIAK, Iva
name: SARNARI, Barbara
name: SCHEMBARI, Emma
name: THISEOS, Maria
Publisher: name: Zenodo
Year: 2019
Subjects: waste management
waste prevention
monitoring
stakeholder involvement

description: The objective of the work package 6 is the testing of the waste prevention and management strategies identified in the 11 pilot cities/regions, according to Participatory process through the Communities of Practice developed in WP3 and engaging local stakeholders in the waste management strategies implementation.

The measures implementing these strategies have been developed, on average, for 4-6 months, starting in May-June and ending in October-November 2018. All the pilot areas implemented from 3 to 5 measures and promoted and tested the WasteApp developed in WP5 for all the implementation phase, as an important tool of the overall communication campaign enhanced at the local level to promote the URBAN-WASTE measures.

These measures covered various topics such as prevention, reuse, and waste collection, sorting and recycling. This report is divided into 11 different reports, one for each pilot city/region, where detailed information regarding stakeholders involved, timing of the implementation, activities performed, results achieved, challenges faces and lessosn learnt from each strategy implemented and tested is included.

The results obtained in this phase will set the basis for the work developed in WP7 on the impact assessment and explotation of results.
Investigations on the effect of post treatment utilizing ultrasonic standing waves on the hardness of laser beam welds in stainless steel
Creators: name: Grajczak, J.
name: Nowroth, C.
name: Long, Y.
name: Twiefel, J.
name: Wallaschek, J.
name: Nothdurft, S.
name: Hermsdorf, J.
name: Kaierle, S.
Publisher: name: Amsterdam [u.a.] : Elsevier
Year: 2022
Subjects: subject: acoustic hardening
subject: acoustic residual softening
subject: laser beam welding
subject: round bars
subject: ultrasonic excitation
subject: Konferenzschrift
subject: Dewey Decimal Classification::600 | Technik
subject: Dewey Decimal Classification::600 | Technik::670 | Industrielle und handwerkliche Fertigung

description: Laser beam welding is precise, quick and highly automatable. Nevertheless, disadvantageous hardness profiles can result and promote cracking. By an ultrasonic post treatment, crystal defects, internal stress and grain structure can be altered to achieve uniform hardness. In the investigations round bars with 30 mm diameter made from stainless steel grade 1.4301 are welded by laser in a rotational process. Ultrasonic excitation is applied utilizing a longitudinal mode of the system. The weld pool is positioned in the node or the antinode of the amplitude distribution. The excitation amplitude varies at 0/2/4 µm and the treatment durations at 0/5/10 min. The welds are evaluated by metallographic cross sections and hardness measurements. The results indicate the effects of acoustic residual softening and hardening. With standard deviations of about 2 %, the weld hardness is decreased by 3 % with nodal excitation and increased by 4 % with antinodal excitation. The difference between weld and base material hardness is not reduced since the base material is hardened at all ultrasonic parameters used.
Structural behavior of Pb$_y$Bi$_{1.95-y}$Sr$_{1.49}$La$_{0.4}$Cu$_{1.15}$O$_{6+δ}$ for 0
Creators: name: Lübben, O.
name: Dudy, L.
name: Krapf, A.
name: Janowitz, C.
name: Manzke, R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: In the Bi cuprates, the presence of a near 1$\times$5 superstructure is well known. Usually, this superstructure is suppressed by the substitution of lead, but there have been reports of a phase separation in so called α and β phases. This paper shows in high detail time how and why the phase separation develops and what happens to the quasi-1$\times$5 superstructure upon lead substitution. For this purpose, the lanthanum- and lead-substituted single-layered superconductor Bi$_{2+z}$Sr$_{2-z}$CuO$_{6+δ}$ has been investigated by scanning tunneling microscopy and low-energy electron diffraction. The La content was kept constant at slightly under-doped concentration while the Pb content was changed systematically. Thermodynamic considerations show that a phase mixture of α and β phases is inevitable.
description: 17 pages, 4 figures
Effect of temperature dependence of PEEK composite material properties in modelling resistive welding
Creators: name: Forghani, Erfan
Publisher: name: University of British Columbia
Year: 2022

description: One of the most important factors playing a major role in the final quality of a thermoplastic composite part is the developed degree of crystallinity, which is directly affected by the thermal history (process cycle). The melt and crystallization kinetics model for PEEK developed by Gordnian [1] is a useful tool for predicting this parameter, and features path dependency, integrated melt and crystallization sub-models, crystallization induction time, effect of temperature rate on melt behavior and finally cold and hot crystallization. However, this model needs to be improved by implementing temperature-dependent inert material models such as specific heat capacity and conductivity. To do this, a comprehensive literature review was conducted on available material properties in the open literature for PEEK, both neat and reinforced by carbon fiber. Additionally, modulated differential scanning calorimetry experiments were conducted to measure the specific heat capacity of PEEK/AS4 prepregs. The effect of thermal modulation parameters as well as thermal contact resistance were studied. Best practices, including identification of a range for modulation parameters and methods for capturing thermal contact resistance effects were determined. Using the best data from the literature, material models were developed. Talbot [2] simulated the welding of a PEEK/AS4 lap-shear joint in as a transient heat transfer problem. As a part of her investigation, the weld quality was judged based on temperature distribution at the end of the heat-up cycle, as a proxy for crystallization. In this thesis, this approach is improved by directly using Gordnian’s melt/crystallization model with both constant and temperature-dependent inert material properties. It is shown that melting can be completed faster than previously suggested. On the other hand, the time to reach maximum crystallinity is longer than originally predicted process time for this particular geometry, as cool-down was previously not considered. The effect of constant vs time-dependent inert material properties affects the predicted processing time by about 2.6 seconds longer processing time for the current case. Although this might be inconsequential for a static weld, it may be significant for continuous resistance welding of more complex geometries or larger sizes.
On possible Chern Classes of stable Bundles on Calabi-Yau threefolds
Creators: name: Andreas, Bjorn
name: Curio, Gottfried
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Algebraic Geometry (math.AG)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Supersymmetric heterotic string models, built from a Calabi-Yau threefold $X$ endowed with a stable vector bundle $V$, usually lead to an anomaly mismatch between $c_2(V)$ and $c_2(X)$; this leads to the question whether the difference can be realized by a further bundle in the hidden sector. In math.AG/0604597 a conjecture is stated which gives sufficient conditions on cohomology classes on $X$ to be realized as the Chern classes of a stable reflexive sheaf $V$; a weak version of this conjecture predicts the existence of such a $V$ if $c_2(V)$ is of a certain form. In this note we prove that on elliptically fibered $X$ infinitely many cohomology classes $c\in H^4(X, {\bf Z})$ exist which are of this form and for each of them a stable SU(n) vector bundle with $c=c_2(V)$ exists.
description: 12 pages latex, minor changes