cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: of Organizational participatory research: a systematic mixed studies review exposing its extra benefits and the key factors associated with them
Creators: name: Bush, Paula
name: Pluye, Pierre
name: Loignon, Christine
name: Granikov, Vera
name: Wright, Michael
name: Jean-Franรงois Pelletier
name: Bartlett-Esquilant, Gillian
name: Macaulay, Ann
name: Haggerty, Jeannie
name: Parry, Sharon
name: Repchinsky, Carol
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Inclusion and exclusion criteria. (DOCX 40 kb)
title: Hochdisperse Ni-Katalysatoren aus Doppelschichthydroxiden für (De-)Hydrierreaktionen
Creators: name: Kaul, Sebastian
Publisher: name: UNSPECIFIED
Year: 2025

description: Layered-Double-Hyroxides (LDH) mit der allgemeinen Summenformel [M_(1−x)^(2+) M_x^(3+) (OH)^2]^(x+) [A^(n−)]_(x/n) ∙ yH2O sind eine spannende Materialklasse zur Herstellung von Katalysatoren für verschiedenste Anwendungen.[1] Sie bestehen aus positiv geladenen Schichten mit dazwischenliegenden Anionen. Damit lassen sich verschiedene Metalle in den LDHs verteilen, was eine gleichmäßige Verteilung der Komponenten sicherstellt. Katalysatoren auf LDH-Basis zeigen daher eine homogene Verteilung der Komponenten sowie hohe Dispersion und Stabilität, weshalb sie für zahlreiche Anwendungen untersucht werden.[2] Eine Anwendung ist die Hydrogenolyse von Glucose zur Herstellung von Plattformchemikalien. Diese Reaktion kann einen wichtigen Schritt darstellen, um die Produktion von Chemikalien von fossilen auf nachwachsende Rohstoffe umzustellen.[3] Eine weitere Anwendung ist die Ammoniakzersetzung. Dabei soll Ammoniak als Wasserstoffträger dienen, um Wasserstoff effizienter transportieren zu können. Denn in den aktuellen Bestrebungen, auf eine Wasserstoffwirtschaft umzustellen, stellt die niedrige Energiedichte von Wasserstoff ein erhebliches Problem dar, da so der Transport des Wasserstoffs teuer wird.[4] Ammoniak kann aufgrund seines hohen Wasserstoffanteils und der etablierten, unkomplizierten Transportprozesse eine wichtige Option sein.[5]
In dieser Arbeit werden Ni_2Al-LDHs hergestellt und als Precursor für Katalysatoren in der Hydrogenolyse von Glucose sowie in der Ammoniakzersetzung eingesetzt. Für die in der Hydrogenolyse eingesetzten LDHs wird ein Verfahren entwickelt, um Wolframatanionen in die LDH-Struktur zu integrieren, da WO_x einen wichtigen Part in dem Reaktionsnetzwerk als aktives Zentrum der Retro-Aldol-Reaktion übernimmt. Diese LDHs werden zusätzlich mit Mg^(2+) und La^(3+) dotiert, um deren Einfluss auf die Reaktion zu untersuchen. Die Katalysatoren für die Ammoniakzersetzung werden ebenfalls mit Mg^(2+), La^(3+) und Fe^(3+) dotiert und deren Einfluss auf die starken basischen Zentren und die Korrelation zur Aktivität wird analysiert.
MOESM4 of The presence of residual gold nanoparticles in samples interferes with the RT-qPCR assay used for gene expression profiling
Creators: name: Sanabria, Natasha
name: Gulumian, Mary
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Computational Biology

description: Additional file 4. Traditional software and statistical analyses.
Thoracibidion lineatocolle
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Thoracibidion
Thoracibidion lineatocolle

description: 97. Thoracibidion lineatocolle (Thomson, 1865)
Distribution: Brazil (Maranhão, Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Paraguay, Argentina (Misiones).
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Understory, Light trap (Luiz de Queiroz), 1 male, 2 females, 14.x.2015, R. C. Barros & V. E. Vendramini & J.P.B Pine leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 16, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
Additional file 1: of Functionalization of Ti-40Nb implant material with strontium by reactive sputtering
Creators: name: GĂśttlicher, Markus
name: Rohnke, Marcus
name: Moryson, Yannik
name: JĂźrgen Thomas
name: Sann, Joachim
name: Lode, Anja
name: Schumacher, Matthias
name: Schmidt, Romy
name: Pilz, Stefan
name: Gebert, Annett
name: Gemming, Thomas
name: JĂźrgen Janek
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: X-ray diffraction data of surface coating. (PDF 134 kb)
Biodistribution of Biomimetic Drug Carriers, Mononuclear Cells, and Extracellular Vesicles, in Nonhuman Primates
Creators: name: Zhao, Yuling
name: Wu, Zhanhong
name: Yuan, Hong
name: Shipley, Steven T.
name: Stewart, Paul W.
name: Perlmutter, Joel S.
name: Massoud, Nicole
name: Frank, Jonathan E.
name: Haney, Matthew J.
name: Pate, Kelly
name: Batrakova, Elena V.
Publisher: name: Wiley
Year: 2021

description:
Discovery of novel drug delivery systems to the brain remains a key task for successful treatment of neurodegenerative disorders. Herein, the biodistribution of immunocyte-based carriers, peripheral blood mononuclear cells (PBMCs), and monocyte-derived EVs are investigated in adult rhesus macaques using longitudinal PET/MRI imaging. 64 Cu-labeled drug carriers are introduced via different routes of administration: intraperitoneal (IP), intravenous (IV), or intrathecal (IT) injection. Whole body PET/MRI (or PET/CT) images are acquired at 1, 24, and 48 h post injection of 64 Cu-labeled drug carriers, and standardized uptake values (SUVmean and SUVmax ) in the main organs are estimated. The brain retention for both types of carriers increases based on route of administration: IP < IV < IT. Importantly, a single IT injection of PBMCs produces higher brain retention compared to IT injection of EVs. In contrast, EVs show superior brain accumulation compared to the cells when administered via IP and IV routes, respectively. Finally, a comprehensive chemistry panel of blood samples demonstrates no cytotoxic effects of either carrier. Overall, living cells and EVs have a great potential to be used for drug delivery to the brain. When identifying the ideal drug carrier, the route of administration could make big differences in CNS drug delivery.
Tropidion breviusculum
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Tropidion
Tropidion breviusculum

description: 98. Tropidion breviusculum (Thomson, 1867)
Distribution: Brazil (Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Paraguay, Argentina (Misiones).
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Understory, Light trap (Luiz de Queiroz), 1 male, 13.ix.2015, R. C. Barros & R. Rockembacher & M.P. Rincão leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 16, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
Brain Targeting and Toxicological Assessment of the Extracellular Vesicle-Packaged Antioxidant Catalase-SKL Following Intranasal Administration in Mice
Creators: name: Walton, Paul A.
name: Haney, Matthew J.
name: Selvakumaran, Sureka
name: Hayes, Sarah H.
name: Batrakova, Elena V.
name: Whitehead, Shawn N.
name: Liu, Qingfan
name: Kiser, Patti
name: Allman, Brian L.
Publisher: name: Springer Nature
Year: 2021

description:
The antioxidant enzyme catalase represents an important therapeutic target due to its role in mitigating cellular reactive oxygen species that contribute to the pathogenesis of many disease states. Catalase-SKL (CAT-SKL), a genetically engineered, peroxisome-targeted, catalase derivative, was developed in order to increase the therapeutic potential of the enzyme, and has previously been shown to be effective in combating oxidative stress in a variety of in vitro and in vivo models, thereby mitigating cellular degeneration and death. In the present study we addressed important considerations for the development of an extracellular vesicle-packaged version of CAT-SKL (evCAT-SKL) as a therapeutic for neurodegenerative diseases by investigating its delivery potential to the brain when administered intranasally, and safety by assessing off-target toxicity in a mouse model. Mice received weekly intranasal administrations of evCAT-SKL or empty extracellular vesicles for 4 weeks. Fluorescent labeling for CAT-SKL was observed throughout all sections of the brain in evCAT-SKL-treated mice, but not in empty extracellular vesicle-treated mice. Furthermore, we found no evidence of gross or histological abnormalities following evCAT-SKL or empty extracellular vesicle treatment in a full-body toxicological analysis. Combined, the successful brain targeting and the lack of off-target toxicity demonstrates that intranasal delivery of extracellular vesicle-packaged CAT-SKL holds promise as a therapeutic for addressing neurological disorders.
PEG-Free Polyion Complex Nanocarriers for Brain-Derived Neurotrophic Factor
Creators: name: Batrakova, Elena V.
name: Finkelstein, Anna
name: Fay, James M.
name: Kabanov, Alexander V.
name: Lim, Chaemin
Publisher: name: MDPI
Year: 2022

description:
Many therapeutic formulations incorporate poly(ethylene glycol) (PEG) as a stealth component to minimize early clearance. However, PEG is immunogenic and susceptible to accelerated clearance after multiple administrations. Here, we present two novel reformulations of a polyion complex (PIC), originally composed of poly(ethylene glycol)113-b-poly(glutamic acid)50 (PEG-PLE) and brain-derived neurotrophic factor (BDNF), termed Nano-BDNF (Nano-BDNF PEG-PLE). We replace the PEG based block copolymer with two new polymers, poly(sarcosine)127-b-poly(glutamic acid)50 (PSR-PLE) and poly(methyl-2-oxazolines)38-b-poly(oxazolepropanoic acid)27-b-poly(methyl-2-oxazoline)38 (PMeOx-PPaOx-PMeOx), which are driven to association with BDNF via electrostatic interactions and hydrogen bonding to form a PIC. Formulation using a microfluidic mixer yields small and narrowly disperse nanoparticles which associate following similar principles. Additionally, we demonstrate that encapsulation does not inhibit access by the receptor kinase, which affects BDNF's physiologic benefits. Finally, we investigate the formation of nascent nanoparticles through a series of characterization experiments and isothermal titration experiments which show the effects of pH in the context of particle self-assembly. Our findings indicate that thoughtful reformulation of PEG based, therapeutic PICs with non-PEG alternatives can be accomplished without compromising the self-assembly of the PIC.
Tropidion hermione
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Tropidion
Tropidion hermione

description: 99. Tropidion hermione (Thomson, 1867)
Distribution: Brazil (Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Bolivia (Santa Cruz), Paraguay, Argentina (Misiones, Corrientes).
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Understory, Light trap (Luiz de Queiroz), 5 males, 6 females, 13.ix.2015, R. C. Barros & R. Rockembacher & M.P. Rincão leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 16, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
Corrigendum to “GDNF-expressing macrophages restore motor functions at a severe late-stage and produce long-term neuroprotective effects at an early-stage of Parkinson's disease in transgenic Parkin Q311X(A) mice”, [J Control Release, 315 (2019) 139–149]
Creators: name: Uvarov, Olga
name: Haney, Matthew J
name: Jin, Yeon S
name: Zhao, Yuling
name: Rodriguez, Myosotys
name: Langworthy, Benjamin
name: Fine, Jason P
name: Lee, Yueh Z
name: Vinod, Natasha
name: Batrakova, Elena V
name: Kabanov, Alexander V
name: El-Hage, Nazira
Publisher: name: Elsevier
Year: 2022

description:
Corrigendum to “GDNF-expressing macrophages restore motor functions at a severe late-stage and produce long-term neuroprotective effects at an early-stage of Parkinson's disease in transgenic Parkin Q311X(A) mice”
Software repository for the NFDI
Creators: name: Usadel, Björn
name: Garth, Christoph
name: von Suchodoletz, Dirk
name: Mühlhaus, Timo
Publisher: name: Zenodo
Year: 2025

description: The poster Software repository for the NFDI was presented at the Base4NFDI User Conference 2024 (https://events.gwdg.de/event/658/) in the Poster Session.
PERTEMUAN 11_MEY, 06, 2024_PENTINGNYA MEMAHAMI PSAK 24(IMBALAN KERJA)_AKUNTANSI KEUANGAN MENGENGAH 2_UNIVERSITAS GRESIK
Creators: name: Dr. Rusdiyanto, SE,. M. Ak,. CH,. CHt
Publisher: name: Zenodo
Year: 2024

description: Capaian Pembelajaran Mata Kuliah (CPMK)

Capaian Pembelajaran Mata Kuliah (CPMK) yang berfokus pada pemahaman tentang imbalan kerja menurut PSAK 24 sangatlah penting dalam konteks akuntansi. Berikut adalah beberapa alasan mengapa pemahaman ini penting:

Kesesuaian dengan Standar Akuntansi: PSAK 24 adalah standar akuntansi yang mengatur pengakuan, pengukuran, dan pengungkapan imbalan kerja oleh entitas. Memahami hal ini penting untuk memastikan bahwa praktik akuntansi perusahaan sesuai dengan standar yang berlaku.

Pengaruh pada Laporan Keuangan: Imbalan kerja merupakan bagian penting dari biaya operasional perusahaan. Pemahaman yang baik tentang bagaimana imbalan kerja diproses dalam laporan keuangan akan memastikan bahwa laporan tersebut memberikan gambaran yang akurat tentang kinerja dan kondisi keuangan perusahaan.

Transparansi dan Pertanggungjawaban: PSAK 24 menekankan pentingnya transparansi dalam mengungkapkan informasi terkait imbalan kerja kepada pemangku kepentingan. Dengan memahami standar ini, profesional akuntansi dapat memastikan bahwa perusahaan memenuhi kewajiban untuk memberikan informasi yang relevan dan berguna kepada pemangku kepentingan.

Manajemen Risiko: Imbalan kerja dapat menjadi faktor risiko yang signifikan bagi perusahaan, terutama jika manajemennya tidak dipahami atau dikelola dengan baik. Pemahaman tentang PSAK 24 membantu profesional akuntansi dalam mengevaluasi risiko terkait imbalan kerja dan mengembangkan strategi manajemen risiko yang tepat.

Kepatuhan Hukum dan Peraturan: PSAK 24 mencerminkan persyaratan hukum dan peraturan terkait imbalan kerja yang berlaku di Indonesia. Memahami standar ini membantu perusahaan untuk memastikan kepatuhan mereka terhadap regulasi yang berlaku dan menghindari risiko litigasi atau sanksi.

Dengan demikian, pemahaman yang baik tentang imbalan kerja menurut PSAK 24 bukan hanya penting untuk tujuan akademis, tetapi juga memiliki implikasi praktis yang signifikan bagi manajemen perusahaan, pemangku kepentingan, dan profesional akuntansi.
Memorization of Named Entities in Fine-tuned BERT Models
Creators: name: Diera, Andor
name: Lell, Nicolas
name: Garifullina, Aygul
name: Scherp, Ansgar
Publisher: name: arXiv
Year: 2022
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Privacy preserving deep learning is an emerging field in machine learning that aims to mitigate the privacy risks in the use of deep neural networks. One such risk is training data extraction from language models that have been trained on datasets, which contain personal and privacy sensitive information. In our study, we investigate the extent of named entity memorization in fine-tuned BERT models. We use single-label text classification as representative downstream task and employ three different fine-tuning setups in our experiments, including one with Differential Privacy (DP). We create a large number of text samples from the fine-tuned BERT models utilizing a custom sequential sampling strategy with two prompting strategies. We search in these samples for named entities and check if they are also present in the fine-tuning datasets. We experiment with two benchmark datasets in the domains of emails and blogs. We show that the application of DP has a detrimental effect on the text generation capabilities of BERT. Furthermore, we show that a fine-tuned BERT does not generate more named entities specific to the fine-tuning dataset than a BERT model that is pre-trained only. This suggests that BERT is unlikely to emit personal or privacy sensitive named entities. Overall, our results are important to understand to what extent BERT-based services are prone to training data extraction attacks.
description: published at CD-MAKE 2023
Tropidion investitum
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Tropidion
Tropidion investitum

description: 100. Tropidion investitum (Martins, 1962)
Distribution: Brazil (Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Bolivia (Santa Cruz), Paraguay, Argentina (Misiones).
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Understory, Light trap (Luiz de Queiroz), 1 male, 1 female, 14.x.2015, R. C. Barros & V. E. Vendramini & J.P.B Pine leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 16, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
Leptin-loaded Extracellular Vesicles Treat Sleep-disordered Breathing in Mice with Obesity
Creators: name: Polotsky, Vsevolod Y.
name: Zhao, Yuling
name: Ahima, Rexford S.
name: Freire, Carla
name: Batrakova, Elena V.
name: Pho, Huy
name: Ramsey, Jacob D.
name: Kim, Lenise
name: Berger, Slava
name: Anokye-Danso, Frederick
name: Kabanov, Alexander V.
name: Kojima, Ryo
Publisher: name: American Thoracic Society
Year: 2022

description:
Sleep-disordered breathing (SDB), obstructive sleep apnea, and obesity hypoventilation are highly prevalent in obesity and have no effective pharmacotherapy. Leptin is a powerful stimulant of ventilatory control and upper airway patency during sleep. Individuals with obesity have high circulating leptin concentrations but are resistant to its beneficial metabolic and respiratory effects. One of the key mechanisms of leptin resistance is the limited permeability of the blood–brain barrier (BBB) to leptin. Leptin resistance has been implicated in the pathogenesis of SDB.
Structural Causal Modeling of Managerial Interventions: What If Managers Had Not Intervened by Doing This?
Creators: name: Lee, Gwendolyn K.
name: Bettis, Rich
Publisher: name: Institute for Operations Research and the Management Sciences (INFORMS)
Year: 2023

description:
Establishing causality beyond association, influence, or correlation is key to informed managerial decisions and interventions. What-if questions such as “What will happen to firm performance if managers intervene by doing this?” and “What if managers had not done this?” can now be formulated and answered by using the tools of structural causal modeling (SCM). SCM tools contribute a systematic methodology for designing and evaluating managerial interventions. Powered by SCM, researchers can increase the precision in theorizing mechanisms and develop the research designs that facilitate causal identification. As a demonstration of how to apply SCM for advancing theory and research design in strategic management, we study why and how the effect of governance mode on firm performance is transmitted through a reduction in the deviation of managerial decision from theory-based prescription. For example, managers may switch to a governance mode that is consistent with the governance mode prescribed according to transaction cost economics (TCE). The insights arising from SCM inform whether switching governance mode for the purpose of aligning with TCE prescription will improve performance, and, if yes, by how much. Beyond TCE, we point to theory-based prescriptions in strategic management that could benefit from using SCM to probe what-if questions. Funding: G. K. Lee acknowledges funding from the National Science Foundation, Division of Social and Economic Sciences, Science of Organizations Program [Grant SES1743044]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/stsc.2022.0169 .
MOESM5 of The presence of residual gold nanoparticles in samples interferes with the RT-qPCR assay used for gene expression profiling
Creators: name: Sanabria, Natasha
name: Gulumian, Mary
Publisher: name: Figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology

description: Additional file 5. Manual assessment of qPCR results.
Tropidion pictipenne
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Tropidion
Tropidion pictipenne

description: 101. Tropidion pictipenne (Martins, 1962)
Distribution: Brazil (São Paulo, Paraná, Santa Catarina), Bolivia (Santa Cruz), Paraguay, Argentina (Misiones, Corrientes).
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Canopy, Light trap (Luiz de Queiroz), 4 males, 5 females, 14.x.2015, R. C. Barros & V. E. Vendramini & J.P.B Pine leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 16, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
Hydrochara caraboides
Creators: name: Litovkin, S. V.
name: Efimov, D. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hydrophilidae
Hydrochara
Hydrochara caraboides

description: 22. Hydrochara caraboides (Linnaeus, 1758)
REFERENCES. Efimov [2010].
MATERIAL EXAMINED. Krapivinskiy, 25.VII.2007, T. Platonova leg. (1 ex.); Krapivinskiy Distr., near “Azhendarovo”, 10.– 22.VIII.2010, 20.–28. V. 2012, 28. V. –03. VI.2014, DE, FB, AK, A. Kostyunin leg. (6 exs.); vicinity of “Azhendarovo”, moth of Bugas River, 54°44´N 87°01´E, 10.–30.VII.2008, AK (2 exs.); Promyshlennovskiy Distr., Morozovo, pool, 22. VI.2012, DE (1 ex.).
DISTRIBUTION. Europe, Northern Africa, Western and Eastern Siberia, Turkey, Iran [Fikáček et al., 2015; Przewoźny, 2019].
– Hydrochara dichroma (Fairmaire, 1892)
REMARKS. Records of this species for the Kemerovo Area [Efimov, 2010] is based on a mistakenly signed specimen of Hydrobius fuscipes (L.).
description: Published as part of Litovkin, S. V. & Efimov, D. A., 2020, Beetles of the superfamily Hydrophiloidea of Kemerovo Area, pp. 61-68 in Russian Entomological Journal 29 (1) on page 64, DOI: 10.15298/rusentj.29.1.08, http://zenodo.org/record/10978301
Questionable Research Practices Distort Impressions of Reality: Comment on Questioning Psychological Constructs
Creators: name: Bollen, Kenneth A.
Publisher: name: Taylor & Francis
Year: 2023

description:
I congratulate De Boeck, Pek, Walton, Wegener, Turner, Andersen, Beauchaine, Lecavalier, Myung, and Petty (this issue) on presenting a thought-provoking piece on the nature of constructs and their role in psychological research. Their paper is a reminder of our sometimes casual use of terms that, upon closer inspection, are at best ambiguous and at worst damaging to scientific progress. De Boeck et al. (this issue) paper encourages us to confront this ambiguity, and they give their take on how we should view constructs. More specifically, they view constructs as hierarchical composites that are variable in nature. Furthermore, they suggest that constructs defined in this manner better reflect reality. They argue that this complexity of reality can explain the "dissatisfactions with the vagueness of constructs, variable results, lack of progress in accumulating knowledge, and … failures to replicate."
An Analysis of Variance of the Pantheon+ Dataset: Systematics in the Covariance Matrix?
Creators: name: Keeley, Ryan
name: Shafieloo, Arman
name: L'Huillier, Benjamin
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We investigate the statistics of the available Pantheon+ dataset. Noticing that the $χ^2$ value for the best-fit $Λ$CDM model to the real data is small, we quantify how significant its smallness is by calculating the distribution of $χ^2$ values for the best-fit $Λ$CDM model fit to mock Pantheon+-like datasets, using the provided covariance matrix. We further investigate the distribution of the residuals of the Pantheon+ dataset with respect to the best-fit $Λ$CDM model, and notice that they scatter less than would be expected from the covariance matrix but find no significant kurtosis. These results point to the conclusion that the Pantheon+ covariance matrix is over-estimated. One simple interpretation of these results is a $\sim$7\% overestimation of errors on SN distance moduli in Pantheon+ data. When the covariance matrix is reduced by subtracting an intrinsic scatter term from the diagonal terms of the covariance matrix, the best-fit $χ^2$ for the $Λ$CDM model achieves a normal value of 1580 and no deviation from $Λ$CDM is detected. We further quantify how consistent the $Λ$CDM model is with respect to the modified data with the subtracted covariance matrix using model-independent reconstruction techniques such as the iterative smoothing method. We find that the standard model is consistent with the data. There are a number of potential explanations for this smallness of the $χ^2$, such as a Malmquist bias at high redshift, or accounting for systematic uncertainties by adding them to the covariance matrix, thus approximating systematic uncertainties as statistical ones.
description: 11 pages, 6 figures, matches the published version
Development of anti-PEG IgG/IgM/IgE ELISA assays for profiling anti-PEG immunoglobulin response in PEG-sensitized individuals and patients with alpha-gal allergy
Creators: name: Li, Zhongbo
name: Miller, Ian
name: Phillips, Elizabeth J
name: Starnes, Rachel
name: Lai, Samuel K
name: Ma, Alice
name: Stone, Cosby A
name: Choudhary, Shailesh K
name: Talkington, Anne
name: Commins, Scott P
Publisher: name: Elsevier
Year: 2024

description: Polyethylene glycol (PEG) is frequently used in various protein and nanomedicine therapeutics. However, various studies have shown that select PEGylated therapeutics can induce production of anti-PEG antibodies (APA), potentially culminating in rapid clearance from the systemic circulation, loss of efficacy and possibly increased risks of allergic reactions. Although IgE is a frequent cause of immediate hypersensitivity reactions (IHR), the role of IgE APA in PEG-related IHR is not well understood, due in part to a lack of standardized assays for measuring IgE APA. Here, we developed a rigorous competitive ELISA method to measure the concentrations of various APA isotypes, including IgE, with picomolar sensitivities. In a small number of serum samples from patients with known PEG allergy, the assay allowed us to detect a strong correlation between IgG and IgE APA in individuals with history of allergic reactions to PEG or PEGylated drugs, but not between IgM and IgE APA. We detected appreciable levels of IgG and IgM APA in individuals with history of alpha-gal allergy, however, they were not elevated relative to those detected in other healthy controls, and we found no pre-existing IgE APA. While preliminary and should be further investigated, these results suggest that differences in the route and mechanism of PEG exposure may drive variability in APA response.
Additional file 1: Table S1. of Prevalence of antimicrobial resistant Escherichia coli from patients with suspected urinary tract infection in primary care, Denmark
Creators: name: CĂłrdoba, Gloria
name: Holm, Anne
name: Hansen, Frank
name: Hammerum, Anette
name: Bjerrum, Lars
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Distribution of susceptible and resistant E. coli isolates in uncomplicated and complicated cases. Table S2. Number of resistant E.coli isolates in uncomplicated and complicated cases. (DOCX 19Â kb)
Meeting the Need: Formal Electrochemistry Training through Workshops
Creators: name: Peroff, Alex G.
name: Dempsey, Jillian L.
name: Jackson, Megan N.
Publisher: name: American Chemical Society (ACS)
Year: 2024

description: A need for enhanced access to formal electrochemistry training has led to the launch of several standalone workshops, including the Cyclic Voltammetry Boot Camp. In this Article, we describe the history of Cyclic Voltammetry Boot Camp, its scope and mission, the structure and content covered during the three-day workshop, and the impact the workshop has had on participants. The workshop is also contextualized through a brief summary of related workshops.
Tropidion signatum subsp. signatum signatum (Audinet-Serville 1834
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Tropidion
Tropidion signatum
Tropidion signatum signatum (audinet-Serville, 1834)

description: 102. Tropidion signatum signatum (Audinet-Serville, 1834)
Distribution: Brazil (Piauí, Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná, Santa Catarina, Rio Grande do Sul), Paraguay, Argentina (Misiones).
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Canopy, Light trap (Luiz de Queiroz), 1 male, 14.x.2015, R. C. Barros & V. E. Vendramini & J.P.B Pine leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 16, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
title: Pflanzliche Souvenirs mit ungeahnten Folgen - Einfuhrbeschränkungen und Einfuhrverbote im Reiseverkehr
Creators: name: Kaminski, Katrin
Publisher: name: Julius Kühn-Institut
publisherIdentifier: https://ror.org/022d5qt08
publisherIdentifierScheme: ROR
Year: 2016
Subjects: subject: pflanzliche Souvenirs
subject: Folgen
subject: Einfuhr aus EU und der Schweiz
subject: Einfuhr aus Nicht-EU-Ländern in Europa und angrenzendem Mittelmeerraum
subject: Einfuhr aus nichteuropäischen Ländern
subject: Einfuhranforderungen
subject: Einfuhrverbote

description: Informationsblatt des JKI
Additional file 2: of Organizational participatory research: a systematic mixed studies review exposing its extra benefits and the key factors associated with them
Creators: name: Bush, Paula
name: Pluye, Pierre
name: Loignon, Christine
name: Granikov, Vera
name: Wright, Michael
name: Jean-Franรงois Pelletier
name: Bartlett-Esquilant, Gillian
name: Macaulay, Ann
name: Haggerty, Jeannie
name: Parry, Sharon
name: Repchinsky, Carol
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Search strategy. (DOCX 29 kb)
Optimal Instrument Selection Using Bayesian Model Averaging for Model Implied Instrumental Variable Two Stage Least Squares Estimators
Creators: name: Henry, Teague R.
name: Bollen, Kenneth A.
name: Fisher, Zachary F.
Publisher: name: Taylor & Francis
Year: 2024

description:
Model-Implied Instrumental Variable Two-Stage Least Squares (MIIV-2SLS) is a limited information, equation-by-equation, noniterative estimator for latent variable models. Associated with this estimator are equation-specific tests of model misspecification. One issue with equation-specific tests is that they lack specificity, in that they indicate that some instruments are problematic without revealing which specific ones. Instruments that are poor predictors of their target variables (“weak instruments”) is a second potential problem. We propose a novel extension to detect instrument-specific tests of misspecification and weak instruments. We term this the Model-Implied Instrumental Variable Two-Stage Bayesian Model Averaging (MIIV-2SBMA) estimator. We evaluate the performance of MIIV-2SBMA against MIIV-2SLS in a simulation study and show that it has comparable performance in terms of parameter estimation. Additionally, our instrument-specific overidentification tests developed within the MIIV-2SBMA framework show increased power to detect specific problematic and weak instruments. Finally, we demonstrate MIIV-2SBMA using an empirical example.
Reinforcement Learning for Rotation Sensing with Ultracold Atoms in an Optical Lattice
Creators: name: Chih, Liang-Ying
name: Holland, Murray
Publisher: name: arXiv
Year: 2022
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, we investigate a design approach of reinforcement learning to engineer a gyroscope in an optical lattice for the inertial sensing of rotations. Our methodology is not based on traditional atom interferometry, that is, splitting, reflecting, and recombining wavefunction components. Instead, the learning agent is assigned the task of generating lattice shaking sequences that optimize the sensitivity of the gyroscope to rotational signals in an end-to-end design philosophy. What results is an interference device that is completely distinct from the familiar Mach-Zehnder-type interferometer. For the same total interrogation time, the end-to-end design leads to a 20-fold improvement in sensitivity over traditional Bragg interferometry.
description: 6 pages, 5 figures, supplementary material
Additional file 2: of Organizational participatory research: a systematic mixed studies review exposing its extra benefits and the key factors associated with them
Creators: name: Bush, Paula
name: Pluye, Pierre
name: Loignon, Christine
name: Granikov, Vera
name: Wright, Michael
name: Jean-Franรงois Pelletier
name: Bartlett-Esquilant, Gillian
name: Macaulay, Ann
name: Haggerty, Jeannie
name: Parry, Sharon
name: Repchinsky, Carol
Publisher: name: Figshare
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Search strategy. (DOCX 29 kb)
Path and Direction Discovery in Individual Dynamic Factor Models: A Regularized Hybrid Unified Structural Equation Modeling with Latent Variable
Creators: name: Bollen, Kenneth A.
name: Ye, Ai
Publisher: name: Taylor & Francis
Year: 2024

description:
There has been an increasing call to model multivariate time series data with measurement error. The combination of latent factors with a vector autoregressive (VAR) model leads to the dynamic factor model (DFM), in which dynamic relations are derived within factor series, among factors and observed time series, or both. However, a few limitations exist in the current DFM representatives and estimation: (1) the dynamic component contains either directed or undirected contemporaneous relations, but not both, (2) selecting the optimal model in exploratory DFM is a challenge, (3) the consequences of structural misspecifications from model selection is barely studied. Our paper serves to advance DFM with a hybrid VAR representations and the utilization of LASSO regularization to select dynamic implied instrumental variable, two-stage least squares (MIIV-2SLS) estimation. Our proposed method highlights the flexibility in modeling the directions of dynamic relations with a robust estimation. We aim to offer researchers guidance on model selection and estimation in person-centered dynamic assessments.
Hydrophilus aterrimus Eschscholtz 1822
Creators: name: Litovkin, S. V.
name: Efimov, D. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Hydrophilidae
Hydrophilus
Hydrophilus aterrimus

description: 23. Hydrophilus aterrimus Eschscholtz, 1822 *
MATERIAL EXAMINED. Kemerovskiy Distr., Beregovoy, at night on road, 18.VIII.1999, Yu. Danchenko leg. (1 ex.); Krapivinskiy Distr., “Azhendarovo”, lake, 54°45´46´´N 87°01´49´´E, 4.VII. 2001, N. Teplova leg. (1 ex.); Kemerovo, near airport, 7.VIII.2003 (2 exs.); Mariinsk, 3.VIII.2004, N. Lobova leg. (1 ex.); Promyshlennaya, 27.VIII.2005, 25.VII.2007, M. Samoshchenko, A. Erin leg. (2 exs.); Yashkinskiy Distr., Yashkino, at light, 06.–7.VIII.2016, V. Akaev leg. (1 ex., coll. V. Akaev).
DISTRIBUTION. Europe except its westernmost parts, Western Siberia, Turkey, Iran, Turkmenistan [Fikáček et al., 2015; Przewoźny, 2019]. New for Kemerovo Area.
REMARKS. See comment for the following species.
– Hydrophilus piceus (Linnaeus, 1758)
REMARKS. All records from the Kemerovo Area previously cited under this name [Efimov, 2010] belong to H. aterrimus. The distribution of the species in Western Siberia as a whole requires clarification.
description: Published as part of Litovkin, S. V. & Efimov, D. A., 2020, Beetles of the superfamily Hydrophiloidea of Kemerovo Area, pp. 61-68 in Russian Entomological Journal 29 (1) on page 64, DOI: 10.15298/rusentj.29.1.08, http://zenodo.org/record/10978301
A Model Implied Instrumental Variable Approach to Exploratory Factor Analysis (MIIV-EFA)
Creators: name: Gates, Kathleen M.
name: Luo, Lan
name: Bollen, Kenneth A.
Publisher: name: Springer Nature
Year: 2024

description:
Spearman (Am J Psychol 15(1):201–293, 1904. https://doi.org/10.2307/1412107) marks the birth of factor analysis. Many articles and books have extended his landmark paper in permitting multiple factors and determining the number of factors, developing ideas about simple structure and factor rotation, and distinguishing between confirmatory and exploratory factor analysis (CFA and EFA). We propose a new model implied instrumental variable (MIIV) approach to EFA that allows intercepts for the measurement equations, correlated common factors, correlated errors, standard errors of factor loadings and measurement intercepts, overidentification tests of equations, and a procedure for determining the number of factors. We also permit simpler structures by removing nonsignificant loadings. Simulations of factor analysis models with and without cross-loadings demonstrate the impressive performance of the MIIV-EFA procedure in recovering the correct number of factors and in recovering the primary and secondary loadings. For example, in nearly all replications MIIV-EFA finds the correct number of factors when N is 100 or more. Even the primary and secondary loadings of the most complex models were recovered when the sample sizes were at least 500. We discuss limitations and future research areas. Two appendices describe alternative MIIV-EFA algorithms and the sensitivity of the algorithm to cross-loadings.
Age-related differences in resting-state, task-related, and structural brain connectivity: graph theoretical analyses and visual search performance
Creators: name: Cohen, Jessica R.
name: Merenstein, Jenna L.
name: Madden, David J.
name: Rudolph, Marc D.
name: Jain, Shivangi
name: Mullin, Hollie A.
Publisher: name: Springer Nature
Year: 2024

description:
Previous magnetic resonance imaging (MRI) research suggests that aging is associated with a decrease in the functional interconnections within and between groups of locally organized brain regions (modules). Further, this age-related decrease in the segregation of modules appears to be more pronounced for a task, relative to a resting state, reflecting the integration of functional modules and attentional allocation necessary to support task performance. Here, using graph-theoretical analyses, we investigated age-related differences in a whole-brain measure of module connectivity, system segregation, for 68 healthy, community-dwelling individuals 18–78 years of age. We obtained resting-state, task-related (visual search), and structural (diffusion-weighted) MRI data. Using a parcellation of modules derived from the participants’ resting-state functional MRI data, we demonstrated that the decrease in system segregation from rest to task (i.e., reconfiguration) increased with age, suggesting an age-related increase in the integration of modules required by the attentional demands of visual search. Structural system segregation increased with age, reflecting weaker connectivity both within and between modules. Functional and structural system segregation had qualitatively different influences on age-related decline in visual search performance. Functional system segregation (and reconfiguration) influenced age-related decline in the rate of visual evidence accumulation (drift rate), whereas structural system segregation contributed to age-related slowing of encoding and response processes (nondecision time). The age-related differences in the functional system segregation measures, however, were relatively independent of those associated with structural connectivity.
Limernaea aurivillii
Creators: name: Barros, Rafael C.
name: Fonseca, Mailson G.
name: Jardim, Marcelo T.
name: Damiani, Vinicius E. Vendramini Bruno C. B.
name: Julio, Carlos E. A.
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Limernaea
Limernaea aurivillii

description: 103. Limernaea aurivillii (Gounelle, 1909)
Distribution: Brazil (Goiás, Mato Grosso do Sul, Maranhão, Paraíba, Piauí, Bahia, Minas Gerais, Espírito Santo, Rio de Janeiro, São Paulo, Paraná), Paraguay.
Material examined: BRASIL, Paraná, Céu Azul, 700 m a.s.l., 25º04’09”S, 53º39’35”W. Understory, Light trap (Luiz de Queiroz), 1 male, 14.x.2015, R. C. Barros & V. E. Vendramini & J.P.B Pine leg. (MZUEL).
description: Published as part of Barros, Rafael C., Fonseca, Mailson G., Jardim, Marcelo T., Damiani, Vinicius E. Vendramini Bruno C. B. & Julio, Carlos E. A., 2020, Species of Cerambycinae (Insecta, Coleoptera, Cerambycidae) from east Paraná State (Brazil), with new geographic records, pp. 1-25 in Zootaxa 4845 (1) on page 17, DOI: 10.11646/zootaxa.4845.1.1, http://zenodo.org/record/4406045
Additional file 1: Table S1. of Prevalence of antimicrobial resistant Escherichia coli from patients with suspected urinary tract infection in primary care, Denmark
Creators: name: CĂłrdoba, Gloria
name: Holm, Anne
name: Hansen, Frank
name: Hammerum, Anette
name: Bjerrum, Lars
Publisher: name: Figshare
Year: 2017
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Distribution of susceptible and resistant E. coli isolates in uncomplicated and complicated cases. Table S2. Number of resistant E.coli isolates in uncomplicated and complicated cases. (DOCX 19Â kb)
title: Atomic force microscopy 3D structural reconstruction of individual particles in the study of amyloid protein assemblies (accepted)
Creators: name: Chitty, Claudia
name: Kuliga, Kinga
name: Xue, Wei-Feng
Publisher: name: University of Kent
Year: 2024

description: Recent developments in Atomic Force Microscopy (AFM) image analysis have made 3D structural reconstruction of individual particles observed on 2D AFM height images a reality. Here, we review the emerging contact point reconstruction AFM (CPR-AFM) methodology and its application in 3D reconstruction of individual helical amyloid filaments in the context of the challenges presented by the structural analysis of highly polymorphous and heterogeneous amyloid protein structures. How individual particle level structural analysis can contribute to resolving the amyloid polymorph structure-function relationships, the environmental triggers leading to protein misfolding and aggregation into amyloid species the influences by the conditions or minor fluctuations in the initial monomeric protein structure on the speed of amyloid fibril formation, and the extent of the different types of amyloid species that can be formed, are discussed. Future perspectives in the capabilities of AFM based 3D structural reconstruction methodology exploiting synergies with other recent AFM technology advances are also discussed to highlight the potential of AFM as an emergent general, accessible and multimodal structural biology tool for the analysis of individual bio-molecules
description: Author's Accepted Manuscript