cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Nano Rice Husk Ash Modified with Acidic Ionic Liquid Bridge: An Efficient Promoter for the Synthesis of 1,2,4-Triazolo Quinazolinones
Creators: name: Mazloumi, Masoumeh
name: Shirini, Farhad
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biochemistry
Physical Sciences not elsewhere classified
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: In this study, a new heterogeneous catalyst was obtained easily and simply from the preparation and consolidation of bis-3-(trimethoxysilylpropyl)-ammonium hydrogen sulfate on nano rice husk ash [RHA-[bip]-NH2+ HSO4–]. After identification this reagent using different techniques including FT-IR, XRD, FESEM, TEM, and TGA, its application as an efficient catalyst was investigated in the acceleration of the preparation of 1,2,4-triazolo quinazolinones. All reactions using this catalyst were performed under solvent-free conditions and all products were obtained in suitable times with high isolated yields without the formation of any by-products. Furthermore, the reusability of the catalyst was investigated during successive three runs.
Additional file 1 of TNFPred: identifying tumor necrosis factors using hybrid features based on word embeddings
Creators: name: Trinh-Trung-Duong Nguyen
name: Nguyen-Quoc-Khanh Le
name: Quang-Thai Ho
name: Dinh-Van Phan
name: Yu-Yen Ou
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 1 Statistical test results. Table S1: F and F-critical values from F-test to test the null hypothesis that two datasets’ variances are equal in terms of single amino acid, dipeptide and tripeptide composition. Table S2: p-values from the unpaired student T-test on single amino acid composition on positive group (18 TNF sequences) and negative group (non-TNF sequences) with the assumption that the variance are equal. Table S3: Top 20 dipeptides with the lowest p-values from the unpaired student T-test on dipeptide composition on positive group (18 TNF sequences) and negative group (non-TNF sequences) with the assumption that the variance are equal. Table S4: Top 20 tripeptides with the lowest p-values from the unpaired student T-test on tripeptide composition on positive group (18 TNF sequences) and negative group (non-TNF sequences) with the assumption that the variance are equal.
Synthesis, Density Functional Theory, Insecticidal Activity, and Molecular Docking of Some N-Heterocycles Derived from 2-((1,3-Diphenyl-1H-Pyrazol-4-yl)Methylene)Malonyl Diisothiocyanate
Creators: name: El-Helw, Eman A. E.
name: Abdelrahman, Aya M.
name: Fahmi, Abdelgawad A.
name: Rizk, Sameh A.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Information Systems not elsewhere classified

description: The extensive pharmacological applications of the pyrazole-based compounds stimulated us to synthesize the highly functionalized, pyrazolylmalonyl diisothiocyanate derivative (2) via treating 2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)malonyl dichloride (1) with ammonium thiocyanate in acetonitrile at room temperature. The diisothiocyanate derivative 2 was subsequently conducted with a double molar ratio of different nitrogen nucleophiles like 4-acetylaniline, 2-aminobenzoic acid, 6-aminothiouracil, 2-aminothiadiazole derivative, hydrazine, phenylhydrazine, thiophene-2-carbohydrazide, 2-hydroxybenzohydrazide, 2-cyanoacetohydrazide, thiourea, thiosemicarbazide, 2-aminoaniline, and thiocarbohydrazide, aiming to construct some valuable heterocyclic systems. The synthesized compounds were screened for their insecticidal activity against healthy late third instar larvae P. interpunctella and Nilaparvata lugens and the results showed that pyrimidinethione, thiadiazolotriazine, and tetrazinethione derivatives exhibited the highest insecticidal potency that are supported by DFT stimulation and their molecular docking.
A straightforward meta-analysis approach for oncology phase I dose-finding studies
Creators: name: Röver, Christian
name: Ursino, Moreno
name: Friede, Tim
name: Zohar, Sarah
Publisher: name: arXiv
Year: 2021
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Phase I early-phase clinical studies aim at investigating the safety and the underlying dose-toxicity relationship of a drug or combination. While little may still be known about the compound's properties, it is crucial to consider quantitative information available from any studies that may have been conducted previously on the same drug. A meta-analytic approach has the advantages of being able to properly account for between-study heterogeneity, and it may be readily extended to prediction or shrinkage applications. Here we propose a simple and robust two-stage approach for the estimation of maximum tolerated dose(s) (MTDs) utilizing penalized logistic regression and Bayesian random-effects meta-analysis methodology. Implementation is facilitated using standard R packages. The properties of the proposed methods are investigated in Monte-Carlo simulations. The investigations are motivated and illustrated by two examples from oncology.
description: 30 pages, 11 figures, 8 tables
New Geometries for Black Hole Horizons
Creators: name: Armas, Jay
name: Blau, Matthias
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We construct several classes of worldvolume effective actions for black holes by integrating out spatial sections of the worldvolume geometry of asymptotically flat black branes. This provides a generalisation of the blackfold approach for higher-dimensional black holes and yields a map between different effective theories, which we exploit by obtaining new hydrodynamic and elastic transport coefficients via simple integrations. Using Euclidean minimal surfaces in order to decouple the fluid dynamics on different sections of the worldvolume, we obtain local effective theories for ultraspinning Myers-Perry branes and helicoidal black branes, described in terms of a stress-energy tensor, particle currents and non-trivial boost vectors. We then study in detail and present novel compact and non-compact geometries for black hole horizons in higher-dimensional asymptotically flat space-time. These include doubly-spinning black rings, black helicoids and helicoidal $p$-branes as well as helicoidal black rings and helicoidal black tori in $D\ge6$.
description: v2: 37pp, 5figures, typos fixed, matches published version
Thermal melting of a quantum electron solid in the presence of strong disorder: Anderson versus Wigner
Creators: name: Vu, DinhDuy
name: Sarma, Sankar Das
Publisher: name: arXiv
Year: 2021
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We consider temperature-induced melting of a Wigner solid in one dimensional (1D) and two dimensional (2D) lattices of electrons interacting via the long-range Coulomb interaction in the presence of strong disorder arising from charged impurities in the system. The system simulates semiconductor-based 2D electron layers where Wigner crystallization is often claimed to be observed experimentally. Using exact diagonalization and utilizing the inverse participation ratio as well as conductance to distinguish between the localized insulating solid phase and the extended metallic liquid phase, we find that the effective melting temperature may be strongly enhanced by disorder since the disordered crystal typically could be in a localized glassy state incorporating the combined nonperturbative physics of both Anderson localization and Wigner crystallization. This disorder-induced enhancement of the melting temperature may explain why experiments often manage to observe insulating disorder-pinned Wigner solids in spite of the experimental temperature being decisively far above the theoretical melting temperature of the pristine Wigner crystal phase in many cases.
description: 5+3 pages, 3+5 figures
Unitarity in composite Higgs approaches with vector resonances
Creators: name: Barducci, D.
name: Cai, H.
name: De Curtis, S.
name: Llanes-Estrada, F. J.
name: Moretti, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We examine a simple Composite Higgs Model (CHM) with vector resonances in addition to the Standard Model (SM) fields in perturbation theory by using the $K$-matrix method to implement unitarity constraints. We find that the $W_LW_L$ scattering amplitude has an additional scalar pole (analogous to the $σ$ meson of QCD) as in generic strongly interacting extensions of the SM. The mass and width of this dynamically generated scalar resonance are large and the mass behaves contrary to the vector one, so that when the vector resonance is lighter, the scalar one is heavier, and vice versa. We also attempt an interpretation of this new resonance. Altogether, the presence of the vector state with the symmetries of the CHM improve the low-energy unitarity behavior also in the scalar-isoscalar channel.
description: 16 pages, 14 figures
Etude de l’effet de la pression de cure sur la microstructure d’un limon stabilisé à la chaux et au liant hydraulique par tomographie in situ à rayons X.
Creators: name: Pigeot, Lucile
Publisher: name: Academic Journal of Civil Engineering
Year: 2024

description: Le présent article propose un développement expérimental qui vise à estimer l’effet d’une pression de confinement sur un sol limoneux stabilisé à la chaux et au liant hydraulique pendant sa cure. En effet, dans les projets d’infrastructures linéaires actuels, les sols stabilisés peuvent être soumis à des contraintes importantes au sein d’ouvrages géotechniques. Afin de montrer que ces conditions de cure favorisent l’hydratation des phases cimentaires, une étude comparative est menée sur des éprouvettes ayant eu une cure de 28 jours avec ou sans pression de confinement. Des analyses de diffractions des rayons X, couramment employées pour suivre l’apparition des phases hydratées au sein des matériaux cimentaires, ne permettent pas de conclure quant à l’évolution de l’hydratation dans le sol stabilisé. En outre, des essais de porosimétrie par intrusion de mercure montrent qu’une cure sous contrainte entraine une apparition plus précoce de la nano-porosité associée aux hydrates. Une utilisation originale d’imageries par tomographie in situ à rayons X offre la possibilité d’appréhender l’évolution de la composition et de la microstructure au sein du matériau en cure confinée. Elle est illustrée par une diminution du volume des particules anhydres et par un affinement de la porosité.
description: Academic Journal of Civil Engineering, Vol 42 No 1 (2024): Special Issue - RUGC 2024
Electrocatalytic Cascade Selective Approach to 3-Aryl-2'H,3H,4H-Spiro{Furo[2,3-с]Chromene-2,5'-Pyrimidine}-2',4,4',6'(1'H,3'H)Tetraones and Its Automatic Screening Docking Studies
Creators: name: Elinson, Michail N.
name: Vereshchagin, Anatoly N.
name: Ryzhkova, Yuliya E.
name: Karpenko, Kirill A.
name: Ryzhkov, Fedor V.
name: Egorov, Mikhail P.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Space Science
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Plant Biology

description: The general electrocatalytic cascade approach was found to medicinally relevant spirobarbituric 2,3-dihydro-4H-furo[2,3-c]chromen-4-one scaffold. This new electrocatalytic fast and efficient reaction of benzylidenebarbiturates and 4-hydroxycoumarin in alcohols in the presence of alkali metal halides as mediators in an undivided cell results in the formation of the substituted unsymmetric spirobarbituric 2,3-dihydro-4H-furo[2,3-с]chromen-4-ones in 72–83% yields. This general and efficient approach avoids traditional recrystallization and chromatographic purification stages. According to screening molecular docking data, all synthesized compounds may be prominent for different medical applications, such as control pain, breast cancer therapies, and treatment of obesity, epilepsy, hypertension, cardiovascular disease and diabetes.
Repair Scheduling in Wireless Distributed Storage with D2D Communication
Creators: name: Pedersen, Jesper
name: Amat, Alexandre Graell i
name: Andriyanova, Iryna
name: Brännström, Fredrik
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: We consider distributed storage (DS) for a wireless network where mobile devices arrive and depart according to a Poisson random process. Content is stored in a number of mobile devices, using an erasure correcting code. When requesting a piece of content, a user retrieves the content from the mobile devices using device-to-device communication or, if not possible, from the base station (BS), at the expense of a higher communication cost. We consider the repair problem when a device that stores data leaves the network. In particular, we introduce a repair scheduling where repair is performed (from storage devices or the BS) periodically. We derive analytical expressions for the overall communication cost of repair and download as a function of the repair interval. We illustrate the analysis by giving results for maximum distance separable codes and regenerating codes. Our results indicate that DS can reduce the overall communication cost with respect to the case where content is only downloaded from the BS, provided that repairs are performed frequently enough. The required repair frequency depends on the code used for storage and the network parameters. In particular, minimum bandwidth regenerating codes require very frequent repairs, while maximum distance separable codes give better performance if repair is performed less frequently. We also show that instantaneous repair is not always optimal.
description: To be presented at IEEE Information Theory Workshop (ITW) 2015, Jeju Island, Korea, October 2015
Modèle chemo-mécanique de carbonatation et de lixiviation du béton dans des conditions hydriques et thermiques variables
Creators: name: IBRAHIM, Layla
Publisher: name: Academic Journal of Civil Engineering
Year: 2024

description: Face aux enjeux environnementaux, les ingénieurs civils ont recours à des études axées sur la durabilité des structures afin de comprendre puis modéliser les différents mécanismes de dégradation du béton. Néanmoins, les modèles définis à l’échelle microscopique ou mésoscopique sont très souvent inadaptés aux calculs à l’échelle de la structure. Cet article présente un modèle thermo-hydro-chimique (THC) basé sur une stratégie multi-échelle, adaptable à l’échelle de la structure et au couplage avec un modèle poro-mécanique du béton et permettant de prévoir le comportement de structures soumises à la carbonatation et la lixiviation. Le modèle chimique intègre la minéralogie du ciment et estime son évolution au cours de la dégradation chimique. L’objectif de cette étude est d’améliorer l’efficacité des calculs pour permettre le couplage du modèle THC avec la mécanique (M) à l’échelle de la structure. L’accroissement d’efficacité numérique du modèle THCM s’appuie sur une méthodologie de « réduction de modèle ». L’équilibre thermodynamique des hydrates de ciment avec la solution de pores est considéré en ramenant la description du béton à quatre variables d’état principales intégrées dans un système de quatre équations bilans non linéaires. L’influence de la température sur la dégradation chimique est prise en compte à travers son impact sur l’équilibre thermodynamique des hydrates et sur la diffusion des espèces. Le modèle estime les différents types d’hydrates et la calcite auxquels sont liés le volume des pores, la quantité d’eau et les propriétés mécaniques. Le modèle a été implémenté dans un code aux éléments finis, et validé par comparaisons avec des résultats expérimentaux de la littérature.
description: Academic Journal of Civil Engineering, Vol 42 No 1 (2024): Special Issue - RUGC 2024
FDG–PET and MRI in Anal Cancer Radiation Therapy: Exploring their Use in Planning, Treatment and Response Assessment
Creators: name: SMITH, DREW WILLIAM GLADSTONE
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 321110
subject: Radiation therapy

description: This thesis explored FDG–PET and MRI in the radiation therapy planning, treatment and response assessment for the relatively rare anal cancer (AC). It has demonstrated the potential and methods of FDG–PET and MRI in targeting and monitoring primary AC throughout a patient’s treatment journey. The methods and data developed as part of this thesis will underpin future research development for this rare cancer in this rapidly evolving era of imaging in radiation therapy.
Synthesis, Spectroscopic (FTIR, FT-Raman and UV-Vis), Structural Investigation, Hirshfeld, AIM, NBO, Chemical Reactivity, In-Vitro and In-Silico Analysis of N-(2-Hydroxyphenyl)-4-Toluenesulfonamide
Creators: name: Subi, Bravanjalin
name: Dhas, D. Arul
name: Joe, I. Hubert
name: Balachandran, S.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Biochemistry
Physical Sciences not elsewhere classified
Cell Biology
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: The prospective antimicrobial molecule N-(2-Hydroxyphenyl)-4-methylbenzene sulfonamide has been synthesized and characterized by single crystal XRD, FT-IR, FT-Raman, UV-Vis spectra and antimicrobial analysis. The quantum chemical computations of energies, geometrical structure, charge transfer and vibrational wavenumbers were carried out using density functional method (DFT/B3LYP) with 6-311 G (d, p) basis set. The complete vibrational assignment for the vibrational modes were performed with vibrational energy distribution analysis (VEDA4) and these assignments were compared with the experimental FT-IR and FT-Raman spectrum. In FT-IR spectrum, strong intense absorption bands are observed at 3408 and 3273 cm−1 corresponding to OH and NH group, which is involved in N–H…O and C–H…O intermolecular interaction. Hirshfeld surface analysis determines the stability of crystal packing within the crystal packing ensured by C–H…O and O–H…O intermolecular interactions. The 2 D fingerprint plot shows that H…H, C…H and O…H interaction exhibit the most significant contribution. Natural bond orbital (NBO) analysis suggests that the electronic transitions are mainly attributed to π→π* transitions. The strength of N–H…O and C–H…O intermolecular interactions were analyzed using reduced density gradient (RDG) analysis and atom in molecule (AIM) analysis. The frontier molecular orbital analysis reveals the possibility of charge transfer within the molecule. Electrophilic and nucleophilic sites were found by molecular electrostatic potential (MEP) analysis and Fukui analysis. Molecular docking shows that sulfonamide and hydroxyl groups are biologically active through their hydrogen bonding interaction with amino acids, which reveals the antimicrobial activity of the compound. Antimicrobial activity of the compound was confirmed by the Kirby Bauer disk diffusion method. The band gap energy and antimicrobial evaluation of the title molecule were compared with the reported relative compounds, which reveals the significant antimicrobial activity. Besides, drug likeness and ADMET (absorption, distribution, metabolism, excretion and toxicity) prediction analysis suggest that the title compound can be used as an antimicrobial drug.
Calculation and evaluation of cross-sections for p+184W reactions up to 200MeV
Creators: name: Sun, Jianping
name: Zhang, Zhengjun
name: Han, Yinlu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The cross-sections of proton-induced reactions on 184W at incident proton energy below 200MeV are calculated and analyzed including reaction cross-sections, elastic scattering angular distributions, energy spectra and double differential cross section. Nuclear theoretical models which integrate the optical model, distorted born wave approximation theory, the intra-nuclear cascade model, the exciton model, the Hauser-Feshbach theory and the evaporation model are used in the reactions. Theoretical results are compared with the existent experimental data.
description: 18 pages,13 figures,3 tables
Quantum Fluctuations in Electrical Multiport Linear Systems
Creators: name: Parra-Rodriguez, A.
name: Egusquiza, I. L.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We present an extension of the classical Nyquist-Thevenin theorem for multiport classical electrical networks by Twiss to the quantum case. Conversely, we extend the quantum fluctuation-dissipation result for one port electrical systems to the multiport case, both reciprocal and nonreciprocal. Our results are extended to lossy systems by depicting resistive components as continuous limits of purely lossless lumped-element networks. Simple circuit examples are analyzed, including a linear system lacking a direct impedance representation.
description: 11 pages. 5 figures
Die Prognose von Studienerfolg und Studienabbruch auf Basis von Umfrage- und administrativen Prüfungsdaten
Creators: name: Pannier, Sören
name: Rendtel, Ulrich
name: Gerks, Hartmut
Publisher: name: Humboldt-Universität zu Berlin
Year: 2020
Subjects: subject: Studienabbruch
subject: Prospektives Erhebungsdesign
subject: Prüfungsdaten
subject: Längsschnitt-Analyse
subject: Study break-off
subject: Prospective survey design
subject: Administrative examination data
subject: Longitudinal analysis
subject: 370 Bildung und Erziehung

description: Die Messung von Studienerfolg bzw. Studienabbruch erfolgt häufig retrospektiv anhand von Exmatrikulierten-Befragungen. Diese Erhebungen sind jedoch mit hohen Nonresponse-Raten verknüpft. Auch die retrospektive Selbsteinschätzung unterliegt Erinnerungsfehlern. Alternativ findet man auch prospektive Ansätze im Rahmen von Panelerhebungen, die jedoch von Stichprobenausfällen zwischen den Befragungswellen betroffen sind. Dieser Artikel präsentiert einen neuen prospektiven Ansatz auf Basis von administrativen Prüfungsdaten und Umfragedaten. Hintergrundinformationen über die Studierenden werden zu Beginn des zweiten Fachsemesters im Rahmen einer Hörsaalbefragung erhoben. Die notwendige Einwilligung der Studierenden zur Verknüpfung mit den Prüfungsdaten wird fast immer erreicht, so dass der Einfluss von Hintergrundmerkmalen, Nebentätigkeit während des Studiums sowie der Studienmotivation auf den Studienabschluss ohne Stichprobenausfälle analysiert werden kann. Dieser Ansatz wurde erstmalig am Fachbereich Wirtschaftswissenschaft der FU Berlin realisiert. Der Aufsatz beschreibt die Durchführung dieses Konzepts sowie Analyseergebnisse für den Studienverlauf und Studienabbrüche. Im Ergebnis erhalten wir, dass sich ein Studienabbruch schon in der Studieneingangsphase anhand der erworbenen Leistungspunkte und der Selbsteinschätzung der Studierenden sehr genau vorhersagen lässt. Hingegen liefern die Schulnote und die sozialen Hintergrundmerkmale keine zusätzliche Information für einen Studienabbruch.
Pyrazole Derivative Containing Naphthalene Moiety: Cytotoxocity (Breast and Cervical Cancer), Antibacterial and Antifungal Studies Using Experimental and Theoretical Tools
Creators: name: Tabassum, Sumaiya
name: Thangaiyan, Pooventhiran
name: Govindaraju, Santhosh
name: Daniel, Nobi K.
name: Thomas, Renjith
Publisher: name: Taylor & Francis
Year: 2022
Subjects: Biophysics
Biochemistry
Molecular Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Virology

description: In the present study, the title compound is named 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(6-methoxynaphthalen-1-yl)methyl)-5-methyl-2-phenyl-1,2-dihydropyrazol-3-one was synthesized, and its antibacterial, antifungal, cytotoxic activity was studied by both experimental and in silico methods. The molecular structure was optimized using DFT/B3LYP method with cc-pVDZ as a besis set, and frontier molecular orbital (FMO) studies was used to explain the physiochemical properties of that molecule by the energy of interacting orbitals. NBO describes the intra delocalization of electrons in the molecule, which support the stability of that molecule. Noncovalent interaction (NCI) explains the nonbond interactions present in the molecule. Drug-likeness property of 405 C have been checked by absorption, distribution, metabolism and excretion (ADME) assay, result shown all the drug-likeness properties in red color region, so we have confirmed this molecule as a drug. 405 C undergoes antibiotic activity against P. aeruginosa organism, antifungal activity against B. cinerea and cytotoxicity activity against MCF-7 and HeLa cell when compared to standard drugs.
Additional file 1 of High-throughput sequencing identification of differentially expressed microRNAs in metastatic ovarian cancer with experimental validations
Creators: name: Gu, Yang
name: Zhang, Shulan
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer

description: Additional file 1: Table S1. Sequences of the negative control, miR-7-5p mimic and inhibitor.
Heavy-Meson Spectrum Tests of the Oktay--Kronfeld Action
Creators: name: Bailey, Jon A.
name: Jang, Yong-Chull
name: Lee, Weonjong
name: DeTar, Carleton
name: Kronfeld, Andreas S.
name: Oktay, Mehmet B.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present heavy-meson spectrum results obtained using the Oktay--Kronfeld (OK) action on MILC asqtad lattices. The OK action was designed to improve the heavy-quark action of the Fermilab formulation, such that heavy-quark discretization errors are reduced. The OK action includes dimension-6 and -7 operators necessary for tree-level matching to QCD through order $\mathrm{O}(Λ^3/m_Q^3)$ for heavy-light mesons and $\mathrm{O}(v^6)$ for quarkonium, or, equivalently, through $\mathrm{O}(a^2)$ with some $\mathrm{O}(a^3)$ terms with Symanzik power counting. To assess the improvement, we extend previous numerical tests with heavy-meson masses by analyzing data generated on a finer ($a \approx 0.12\;$fm) lattice with the correct tadpole factors for the $c_5$ term in the action. We update the analyses of the inconsistency parameter and the hyperfine splittings for the rest and kinetic masses.
description: 7 pages, 7 figures, Lattice 2014 proceeding
Word embeddings for topic modeling: an application to the estimation of the economic policy uncertainty index
Creators: name: Belmonte, Hairo U. Miranda
name: Muñiz-Sánchez, Victor
name: Corona, Francisco
Publisher: name: arXiv
Year: 2021
Subjects: subject: Machine Learning (cs.LG)
subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Quantification of economic uncertainty is a key concept for the prediction of macro economic variables such as gross domestic product (GDP), and it becomes particularly relevant on real-time or short-time predictions methodologies, such as nowcasting, where it is required a large amount of time series data, commonly with different structures and frequencies. Most of the data comes from the official agencies statistics and non-public institutions, however, relying our estimates in just the traditional data mentioned before, have some disadvantages. One of them is that economic uncertainty could not be represented or measured in a proper way based solely in financial or macroeconomic data, another one, is that they are susceptible to lack of information due to extraordinary events, such as the current COVID-19 pandemic. For these reasons, it is very common nowadays to use some non-traditional data from different sources, such as social networks or digital newspapers, in addition to the traditional data from official sources. The economic policy uncertainty (EPU) index, is the most used newspaper-based indicator to quantify the uncertainty, and is based on topic modeling of newspapers. In this paper, we propose a methodology to estimate the EPU index, which incorporates a fast and efficient method for topic modeling of digital news based on semantic clustering with word embeddings, allowing to update the index in real-time, which is a drawback with another proposals that use computationally intensive methods for topic modeling, such as Latent Dirichlet Allocation (LDA). We show that our proposal allow us to update the index and significantly reduces the time required for new document assignation into topics.
description: Preprint version
title: „Kein Mensch auf dem Lande kann sich vorstellen, wie es Einem zu Muthe ist, wenn die See hoch geht“
title: Schweizer auf dem Weg nach Amerika
titleType: Other
Creators: name: August, Sabine
Publisher: name: Karl-Franzens-Universität Graz
Year: 2015

description: Mobile Culture Studies. The Journal; Volume 2015 (1); Issue 1;
  Seitenzahl: 85-103; ISSN: 2413-9181;
Additional file 1 of Assessment of burnout in medical students using the Maslach Burnout Inventory-Student Survey: a cross-sectional data analysis
Creators: name: Obregon, Michael
name: Luo, Jessica
name: Shelton, Jarod
name: Blevins, Terri
name: MacDowell, Martin
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Additional file 1.
Nonequilibrium superconducting thin films with sub-gap and pair-breaking photon illumination
Creators: name: Guruswamy, Tejas
name: Goldie, David J.
name: Withington, Stafford
Publisher: name: arXiv
Year: 2015
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We calculate nonequilibrium quasiparticle and phonon distributions for a number of widely-used low transition temperature thin-film superconductors under constant, uniform illumination by sub-gap probe and pair-breaking signal photons simultaneously. From these distributions we calculate material-characteristic parameters that allow rapid evaluation of an effective quasiparticle temperature using a simple analytical expression, for all materials studied (Mo, Al, Ta, Nb, and NbN) for all photon energies. We also explore the temperature and energy-dependence of the low-energy quasiparticle generation efficiency $η$ by pair-breaking signal photons finding $η\approx 0.6$ in the limit of thick films at low bath temperatures that is material-independent. Taking the energy distribution of excess quasiparticles into account, we find $η\to 1$ as the bath temperature approaches the transition temperature in agreement with the assumption of the two-temperature model of the nonequilibrium response that is appropriate in that regime. The behaviour of $η$ with signal frequency scaled by the superconducting energy gap is also shown to be material-independent, and is in qualitative agreement with recent experimental results. An enhancement of $η$ in the presence of sub-gap (probe) photons is shown to be most significant at signal frequencies near the superconducting gap frequency and arises due to multiple photon absorption events that increase the average energy of excess quasiparticles above that in the absence of the probe.
description: 9 pages, 7 figures
Fe3O4@Nano-Walnut Shell/BIII as a New Natural Based Catalyst for Synthesis of Tetrahydrobenzo[a]Xanthene-11-One Derivatives
Creators: name: Abad, Saeed Sharifi Sharif
name: Mirjalili, Bi Bi Fatemeh
name: Bamoniri, Abdolhamid
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Mental Health

description: In this work, Fe3O4@nano-walnut shell/BIII (FNWSB), as a reusable and new catalyst was prepared and then characterized by FT-IR, XRD, FESEM, EDS-MAP, and TGA. This catalyst was used for synthesis of tetrahydrobenzo[a]xanthen-11-ones via three-component, one-pot condensation reaction of dimedone, β-naphthol, and aromatic aldehydes. An uncomplicated work-up, high yields of product, short reaction times, and use of low-cost catalyst are considerable advantages of this procedure.
WKB Approximation with Conformable Operator
Creators: name: Al-Masaeed, Mohamed.
name: Rabei, Eqab. M.
name: Al-Jamel, Ahmed
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, the WKB method is extended to be applicable for conformable Hamiltonian systems where the concept of conformable operator with fractional order $α$ is used. The WKB approximation for the $α$-wavefunction is derived when the potential is slowly varying in space. The paper is furnished with some illustrative examples to demonstrate the method. The quantities of the conformable form are found to be inexact agreement with traditional quantities when $α=1$.
Search for invisible decays of the Higgs boson produced in association with a hadronically decaying vector boson in $pp$ collisions at $\sqrt{s}$ = 8 TeV with the ATLAS detector
Creators: name: ATLAS Collaboration
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: A search for Higgs boson decays to invisible particles is performed using 20.3 fb$^{-1}$ of $pp$ collision data at a centre-of-mass energy of 8 TeV recorded by the ATLAS detector at the Large Hadron Collider. The process considered is Higgs boson production in association with a vector boson ($V$ = $W$ or $Z$) that decays hadronically, resulting in events with two or more jets and large missing transverse momentum. No excess of candidates is observed in the data over the background expectation. The results are used to constrain $VH$ production followed by $H$ decaying to invisible particles for the Higgs mass range $115
description: 14 pages plus author list + cover pages (35 pages total), 6 figures, 5 tables, submitted to EPJC, All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HIGG-2014-07/
Reversible self-Kerr-nonlinearity in an N-type atomic system through a switching field
Creators: name: Yang, Xu
name: Ying, Kang
name: Niu, Yueping
name: Gong, Shangqing
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: We investigate the self-Kerr nonlinearity of a four-level N-type atomic system in 87Rb and observe its reversible property with the unidirectional increase of the switching field. For the laser arrangement that the probe field interacts with the middle two states, the slope and the sign of the self-Kerr nonlinearity around the atomic resonance can not only be changed from negative to positive, but also can be changed to negative again with the unidirectional increasing of the switching field. Numerical simulation agrees very well with the experimental results and dressed state analysis is presented to explain the experimental results.
Quadrupolar magnetic excitations in an isotropic spin-1 antiferromagnet
Creators: name: Nag, A.
name: Nocera, A.
name: Agrestini, S.
name: Garcia-Fernandez, M.
name: Walters, A. C.
name: Cheong, Sang-Wook
name: Johnston, S.
name: Zhou, Ke-Jin
Publisher: name: arXiv
Year: 2021
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The microscopic origins of emergent behaviours in condensed matter systems are encoded in their excitations. In ordinary magnetic materials, single spin-flips give rise to collective dipolar magnetic excitations called magnons. Likewise, multiple spin-flips can give rise to multipolar magnetic excitations in magnetic materials with spin $\mathbf{S} \boldsymbol{\ge} \mathbf{1}$. Unfortunately, since most experimental probes are governed by dipolar selection rules, collective multipolar excitations have generally remained elusive. For instance, only dipolar magnetic excitations have been observed in isotropic $\mathbf{S}\boldsymbol{=}\mathbf{1}$ Haldane spin systems. Here, we unveil a hidden quadrupolar constituent of the spin dynamics in antiferromagnetic $\mathbf{S}\boldsymbol{=}\mathbf{1}$ Haldane chain material Y$_\mathbf{2}$BaNiO$_\mathbf{5}$ using Ni $\mathbf{L_3}$-edge resonant inelastic x-ray scattering. Our results demonstrate that pure quadrupolar magnetic excitations can be probed without direct interactions with dipolar excitations or anisotropic perturbations. Originating from on-site double spin-flip processes, the quadrupolar magnetic excitations in Y$_\mathbf{2}$BaNiO$_\mathbf{5}$ show a remarkable dual nature of collective dispersion. While one component propagates as non-interacting entities, the other behaves as a bound quadrupolar magnetic wave. This result highlights the rich and largely unexplored physics of higher-order magnetic excitations.
Optomechanical Response of a Strongly Interacting Fermi Gas
Creators: name: Helson, Victor
name: Zwettler, Timo
name: Roux, Kevin
name: Konishi, Hideki
name: Uchino, Shun
name: Brantut, Jean-Philippe
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study a Fermi gas with strong, tunable interactions dispersively coupled to a high-finesse cavity. Upon probing the system along the cavity axis, we observe a strong optomechanical Kerr nonlinearity originating from the density response of the gas to the intracavity field and measure it as a function of interaction strength. We find that the zero-frequency density response function of the Fermi gas increases by a factor of two from the Bardeen-Cooper-Schrieffer to the Bose-Einstein condensate regime. The results are in quantitative agreement with a theory based on operator-product expansion, expressing the density response in terms of universal functions of the interactions, the contact and the internal energy of the gas. This provides an example of a driven-dissipative, strongly correlated system with a strong nonlinear response, opening up perspectives for the sensing of weak perturbations or inducing long-range interactions in Fermi gases.
description: 11 pages, 7 figures
Design, Synthesis of Some Innovative Indolo[3,2-c]Isoquinoline-5-One Analogs and Associated Bioactivities, Pharmacophore, Molecular Docking, MEP, and Conceptual DFT Studies
Creators: name: Verma, Vaijinath A.
name: Shinde, Venkat M.
name: Saundane, Anand R.
name: Meti, Rajkumar S.
name: Vennapu, Dushyanth R.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: A series of novel triazolothiadiazolethione and triazolothiadiazine appended indolo[3,2-c]isoquinoline-5-one were designed, synthesized, and validated by IR, 1H, 13C NMR, and mass spectroscopy strategies. All compounds are determined by their DFT investigations with B3LYP/def2-TZVP basis set level, ionization potentials, and electron affinities at vertical (IPv and EAv) and adiabatic parameters (IPA and EAA). Compound 3a has demonstrated the greatest values for these parameters. The compounds’ HOMO-LUMO (FMOs) and MEP maps were performed. The optimized structure of the compounds was estimated in global hardness, softness, global electrophilicity, and dipole moment. To find new drug candidates, different in vitro biological activities were implemented employing antimicrobial activity: Gram-negative bacteria were significantly suppressed by compound 4a, whereas gram-positive bacteria were strongly inhibited by compounds 3c and 3a has significant antifungal and anticancer effects. Compound 4b is profoundly antioxidant with IC50 value of 8.74 ± 1.93 µg/mL and MIC value of 0.25 µg/mL for antituberculosis properties. Thereafter, all of the compounds were subjected to e-pharmacophore approach to molecular docking studies. Compound 4a exhibited the best docking score (−8.458 kcal/mol) and docking interactions with active binding sites of 1TL8 receptor.
Lime activation of fly ash in mortar in the presence of metakaolin
Creators: name: Khatib, J. M.
name: Onaidhe, E.
name: Sonebi, M.
name: Abdelgader, H.
Publisher: name: Academic Journal of Civil Engineering
Year: 2015

description: The effect fly ash activated with lime in the presence of metakaolin on selected properties of mortars is investigated. This work is aimed at producing mortar without the use of cement as a binder in order to reduce the environmental impact of traditional mortar or concrete applications. Two mortar mixes were prepared to conduct this study. The first mix was the control mix with proportion 1 (cement): 3 (sand) and the water to cement ratio was 0.6. In the second mix, the binder consisted of 80% fly ash, 5% lime and 15% metakaolin (by weight). Specimens were cured for different time at 20°C and no elevated temperatures were used. The result shows that the mortar containing fly ash had its highest compressive strength of 0.46MPa and it is much lower than the control. Also the density of the predominantly fly ash mix had a lower density at all ages when compared with the control mix.
description: Academic Journal of Civil Engineering, Vol 33 No 2 (2015): Special Issue - ICBBM 2015
Additional file 2 of TNFPred: identifying tumor necrosis factors using hybrid features based on word embeddings
Creators: name: Trinh-Trung-Duong Nguyen
name: Nguyen-Quoc-Khanh Le
name: Quang-Thai Ho
name: Dinh-Van Phan
name: Yu-Yen Ou
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 2 Visualization of feature sets. Fig. S1a: Visualization corresponding to protein feature vectors comprised from 1-g embedding vectors with perplexity equal to 25. Fig. S1b: Visualization corresponding to protein feature vectors comprised from 1-g embedding vectors with perplexity equal to 50. Fig. S2a: Visualization corresponding to protein feature vectors comprised from 2-g embedding vectors with perplexity equal to 25. Fig. S2b: Visualization corresponding to protein feature vectors comprised from 2-g embedding vectors with perplexity equal to 50. Fig. S3a: Visualization corresponding to protein feature vectors comprised from 3-g embedding vectors with perplexity equal to 25. Fig. S3b: Visualization corresponding to protein feature vectors comprised from 3-g embedding vectors with perplexity equal to 50. Fig. S4a: Visualization corresponding to protein feature vectors comprised from 4-g embedding vectors with perplexity equal to 25. Fig. S4b: Visualization corresponding to protein feature vectors comprised from 4-g embedding vectors with perplexity equal to 50. Fig. S5a: Visualization corresponding to protein feature vectors comprised from 5-g embedding vectors with perplexity equal to 25. Fig. S5b: Visualization corresponding to protein feature vectors comprised from 5-g embedding vectors with perplexity equal to 50. Fig. S6a: Visualization corresponding to protein feature vectors comprised from 1-g and 2-g embedding combined vectors with perplexity equal to 25. Fig. S6b: Visualization corresponding to protein feature vectors comprised from 1-g and 2-g embedding combined vectors with perplexity equal to 50. Fig. S7a: Visualization corresponding to protein feature vectors comprised from 1-g and 3-g embedding combined vectors with perplexity equal to 25. Fig. S7b: Visualization corresponding to protein feature vectors comprised from the combination of 1-g and 3-g embedding combined vectors with perplexity equal to 50. Fig. S8a: Visualization corresponding to protein feature vectors comprised from 2-g and 3-g embedding combined vectors with perplexity equal to 25. Fig. S8b: Visualization corresponding to protein feature vectors comprised from the combination of 2-g and 3-g embedding combined vectors with perplexity equal to 50.
A religious, ethical and philosophical study of the human person in the context of biomedical practices
Creators: name: Milne, Douglas
Publisher: name: Australian Catholic University
Year: 2006

description: From the book of Genesis the human person is presented as divine image-bearer, a Godlike status that is further explained in terms of the dual constitution of matter and spirit. Natural Law provides a person-centred ethic that draws on a number of human goods that emanate naturally from the human person and lead in practice to human flourishing. This theory empowers towards making ethical decisions in the interest of human persons. Aristotle explained the human being as a substantially existing entity with rational powers. By means of his form-matter scheme he handed on, by way of Boethius, to Aquinas, a ready model for the Christian belief in the dual nature of the human person as an ensouled body or embodied soul. Applying the new scientific method to the question of the human self David Hume concluded that he could neither prove nor disprove her existence. By so reasoning Hume indirectly pointed to the need for other disciplines than empirical science to explain the human person. Emmanuel Levinas has drawn on the metaphysical tradition to draw attention to the social and ethical nature of the human person as she leaves the trace of her passing through the face of the other person who is encountered with an ethical gravitas of absolute demand. The genesis of the human person most naturally begins at conception at which point and onwards the human embryo grows continuously through an internal, animating principle towards a full-grown adult person. The main conclusion is that biblical anthropology and metaphysical philosophy provide the needed structures and concepts to explain adequately the full meaning of the human person and to establish the moral right of the human person at every stage to respect and protection.