cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Drawing the self : race and identity in the manga of Tezuka Osamu
Creators: name: Whaley, Benjamin Evan
Publisher: name: University of British Columbia
Year: 2012

description: This thesis explores the construction and mutability of the Japanese race and ethnicity in the print comics of Dr. Tezuka Osamu (1928–1989), Japan’s “god of manga” and the creator of such beloved series as Astro Boy and Kimba the White Lion. By investigating three of Tezuka’s mature, lesser-known works from the 1970s and 80s, I will illustrate how Tezuka’s narratives have been shaped by his consciousness of racial issues and his desire to investigate the changing nature of Japanese identity in the postwar era. First, the works are contextualized within the larger manga history of the 1960s and 70s, specifically the gekiga (lit. drama pictures) movement that heralded more mature and sophisticated stories and artwork. Chapter one analyzes Ode to Kirihito (1970–71, 2006 English), and introduces Julia Kristeva’s theory of abjection to show the ways in which Tezuka bestializes his ethnically Japanese protagonists and turns them into a distinct class of subaltern. Chapter two examines intersections between race and war narratives using Adolf (1983–85, 1995–96 English), Tezuka’s WWII epic about the Jewish Holocaust. The concept of hybridity is utilized and the case is made that Tezuka ultimately denies his racially mixed characters the benefits of their Japanese identity. Chapter three investigates the manifestation of Japanese masculinity in Gringo (1987–89), one of Tezuka’s final works. In this chapter, Japanese identity, masculinity, and sexual ability are linked to the national sport of sumo wrestling. A discussion of diasporic communities is included in order to discuss how the Japanese race is conceptualized as it moves through different geographical and cultural spaces.
Indefinite causal order for quantum phase estimation with Pauli noise
Creators: name: Chapeau-Blondeau, Francois
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: Signal Processing (eess.SP)
subject: FOS: Physical sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This letter further explores the recent scheme of switched quantum channels with indefinite causal order applied to the reference metrological task of quantum phase estimation in the presence of noise. We especially extend the explorations, previously reported with depolarizing noise and thermal noise, to the class of Pauli noises, important to the qubit and not previously addressed. Nonstandard capabilities, not accessible with standard quantum phase estimation, are exhibited and analyzed, with significant properties that are specific to the Pauli noises, while other properties are found in common with the depolarizing noise or the thermal noise. The results show that the presence and the type of quantum noise are both crucial to the determination of the nonstandard capabilities from the switched channel with indefinite causal order, with a constructive action of noise reminiscent of stochastic resonance phenomena. The study contributes to a more comprehensive and systematic characterization of the roles and specificities of quantum noise in the operation of the novel devices of switched quantum channels with indefinite causal order.
description: 8 pages, 2 figures, 22 references
Simulations of stellar convection with CO5BOLD
Creators: name: Freytag, Bernd
name: Steffen, Matthias
name: Ludwig, Hans-Günter
name: Wedemeyer-Böhm, Sven
name: Schaffenberger, Werner
name: Steiner, Oskar
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: High-resolution images of the solar surface show a granulation pattern of hot rising and cooler downward-sinking material -- the top of the deep-reaching solar convection zone. Convection plays a role for the thermal structure of the solar interior and the dynamo acting there, for the stratification of the photosphere, where most of the visible light is emitted, as well as for the energy budget of the spectacular processes in the chromosphere and corona. Convective stellar atmospheres can be modeled by numerically solving the coupled equations of (magneto)hydrodynamics and non-local radiation transport in the presence of a gravity field. The CO5BOLD code described in this article is designed for so-called "realistic" simulations that take into account the detailed microphysics under the conditions in solar or stellar surface layers (equation-of-state and optical properties of the matter). These simulations indeed deserve the label "realistic" because they reproduce the various observables very well -- with only minor differences between different implementations. The agreement with observations has improved over time and the simulations are now well-established and have been performed for a number of stars. Still, severe challenges are encountered when it comes to extending these simulations to include ideally the entire star or substellar object: the strong stratification leads to completely different conditions in the interior, the photosphere, and the corona. Simulations have to account for a large range of spatial and time scales and also non-equilibrium processes. Last but not least, realistic simulations are based on detailed microphysics and depend on the quality of the input data. This article provides an overview of the physical problem and the numerical solution and the capabilities of CO5BOLD, illustrated with a number of applications.
Fermi surface topology of LaFePO and LiFeP
Creators: name: Ferber, Johannes
name: Jeschke, Harald O.
name: Valenti, Roser
Publisher: name: arXiv
Year: 2012
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We perform charge self-consistent LDA+DMFT (density functional theory combined with dynamical mean field theory) calculations to study correlation effects on the Fermi surfaces of the iron pnictide superconductors LaFePO and LiFeP. We find a distinctive change in the topology of the Fermi surface in both compounds where a hole pocket with Fe dz^2 orbital character changes its geometry from a closed shape in LDA to an open shape upon inclusion of correlations.
description: 5 pages, 4 figures; updated version, slightly extended discussion + nicer figures
Using focus groups to design systems science models that promote oral health equity
Creators: name: Kum, Susan S.
name: Northridge, Mary E.
name: Metcalf, Sara S.
Publisher: name: Columbia University
Year: 2018
Subjects: Dental care
Minorities--Health and hygiene
Multiagent systems
Focus groups
Older people--Dental care
Social medicine

description: Background
                While the US population overall has experienced improvements in oral health over the past 60 years, oral diseases remain among the most common chronic conditions across the life course. Further, lack of access to oral health care contributes to profound and enduring oral health inequities worldwide. Vulnerable and underserved populations who commonly lack access to oral health care include racial/ethnic minority older adults living in urban environments. The aim of this study was to use a systematic approach to explicate cause and effect relationships in creating a causal map, a type of concept map in which the links between nodes represent causality or influence.

                Methods
                To improve our mental models of the real world and devise strategies to promote oral health equity, methods including system dynamics, agent-based modeling, geographic information science, and social network simulation have been leveraged by the research team. The practice of systems science modeling is situated amidst an ongoing modeling process of observing the real world, formulating mental models of how it works, setting decision rules to guide behavior, and from these heuristics, making decisions that in turn affect the state of the real world. Qualitative data were obtained from focus groups conducted with community-dwelling older adults who self-identify as African American, Dominican, or Puerto Rican to elicit their lived experiences in accessing oral health care in their northern Manhattan neighborhoods.

                Results
                The findings of this study support the multi-dimensional and multi-level perspective of access to oral health care and affirm a theorized discrepancy in fit between available dental providers and patients. The lack of information about oral health at the community level may be compromising the use and quality of oral health care among racial/ethnic minority older adults.

                Conclusions
                Well-informed community members may fill critical roles in oral health promotion, as they are viewed as highly credible sources of information and recommendations for dental providers. The next phase of this research will involve incorporating the knowledge gained from this study into simulation models that will be used to explore alternative paths toward improving oral health and health care for racial/ethnic minority older adults.
Additional file 1 of Automated classification of protein expression levels in immunohistochemistry images to improve the detection of cancer biomarkers
Creators: name: Xue, Zhen-Zhen
name: Li, Cheng
name: Luo, Zhuo-Ming
name: Wang, Shan-Shan
name: Xu, Ying-Ying
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1. Table S-1. Comparison of different architectures of deep neural networks. Table S-2. Results of deep learning features.
Efficient data compression from statistical physics of codes over finite fields
Creators: name: Braunstein, Alfredo
name: Kayhan, Farbod
name: Zecchina, Riccardo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Information Theory (cs.IT)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Computer and information sciences
subject: FOS: Physical sciences

description: In this paper we discuss a novel data compression technique for binary symmetric sources based on the cavity method over a Galois Field of order q (GF(q)). We present a scheme of low complexity and near optimal empirical performance. The compression step is based on a reduction of sparse low density parity check codes over GF(q) and is done through the so called reinforced belief-propagation equations. These reduced codes appear to have a non-trivial geometrical modification of the space of codewords which makes such compression computationally feasible. The computational complexity is O(d.n.q.log(q)) per iteration, where d is the average degree of the check nodes and n is the number of bits. For our code ensemble, decompression can be done in a time linear in the code's length by a simple leaf-removal algorithm.
description: 10 pages, 4 figures
title: The role of vector-derived microbiota and co-localization in the dissemination of vector transmitted pathogens
Creators: name: Melo, Léon
Publisher: name: Arts
Year: 2024
Subjects: subject: sandfly microbiota
subject: Leishmania
subject: Dissemination
subject: Visceral leishmaniasis
subject: Vector microbiota
subject: IL-1B
subject: Immunology
subject: FOS: Clinical medicine
subject: Neutrophils
subject: Leishmania infantum
subject: Education--Sciences
subject: Education--Health
subject: Immunology

description: Visceral Leishmaniasis poses significant challenges to prophylactic vaccination and treatment strategies due to the ability of Leishmania spp. parasites to disseminate from the initial site of infection in the skin to the internal organs following transmission by the bite of an infected sand fly vector. This study investigated the role of inoculation method and the vector, sand fly gut-derived microbiota in modulating the host immune response and facilitating parasite dissemination. Utilizing a novel skin prick model that closely mimics natural sand fly transmission, we explored the influence of sand fly gut-derived (SFGD) bacteria on neutrophil recruitment, IL-1β production, and parasite dissemination in both wild-type and IL-1β-deficient mice. Our findings reveal an enhanced influx of neutrophils IL-1β+ in the early stages of infection, underscoring the importance of vector-derived microbiota in shaping the initial immune response. However, the absence of a significant impact of SFGD bacteria on dissemination or parasite burden challenges the hypothesis and previously published observations that SFGD bacteria facilitate dissemination. While we observed that IL-1β deficiency did not significantly alter parasite dissemination overall, a specific increase in liver burden was observed in IL-1β-/- mice exposed to SFGD bacteria, suggesting a potential liver-specific role of IL-1β in the control of disseminated parasite burden. This study highlights the complex interplay between host, pathogen, and vector-derived factors in Leishmania pathogenesis and opens avenues for further investigation into the molecular mechanisms driving these interactions. Future research should focus on the quantification of the inoculated bacterial load during transmission, the broader impacts of SFGD bacteria on other immune cell populations, the role of the host skin microbiota, and the potential therapeutic targeting of IL-1β to mitigate visceral leishmaniasis.
Efficient energy transport in an organic semiconductor mediated by transient exciton delocalization.
Creators: name: Sneyd, Alexander J
name: Fukui, Tomoya
name: Paleček, David
name: Prodhan, Suryoday
name: Wagner, Isabella
name: Zhang, Yifan
name: Sung, Jooyoung
name: Collins, Sean M
name: Slater, Thomas J A
name: Andaji-Garmaroudi, Zahra
name: MacFarlane, Liam R
name: Garcia-Hernandez, J Diego
name: Wang, Linjun
name: Whittell, George R
name: Hodgkiss, Justin M
name: Chen, Kai
name: Beljonne, David
name: Manners, Ian
name: Friend, Richard H
name: Rao, Akshay
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021

description: Efficient energy transport is desirable in organic semiconductor (OSC) devices. However, photogenerated excitons in OSC films mostly occupy highly localized states, limiting exciton diffusion coefficients to below ~10-2 cm2/s and diffusion lengths below ~50 nm. We use ultrafast optical microscopy and nonadiabatic molecular dynamics simulations to study well-ordered poly(3-hexylthiophene) nanofiber films prepared using living crystallization-driven self-assembly, and reveal a highly efficient energy transport regime: transient exciton delocalization, where energy exchange with vibrational modes allows excitons to temporarily re-access spatially extended states under equilibrium conditions. We show that this enables exciton diffusion constants up to 1.1 ± 0.1 cm2/s and diffusion lengths of 300 ± 50 nm. Our results reveal the dynamic interplay between localized and delocalized exciton configurations at equilibrium conditions, calling for a re-evaluation of exciton dynamics and suggesting design rules to engineer efficient energy transport in OSC device architectures not based on restrictive bulk heterojunctions.
From sensors to citizens : exploring the tensions of using Web 2.0 technologies to support online volunteerism
Creators: name: Martin, Michael Evans
Publisher: name: University of British Columbia
Year: 2012

description: This thesis explores the collaborative and social elements of Web 2.0 and its application to online volunteering by Canadian geographers for African non-governmental organizations. Specifically, it looks beyond the binary issues of access and motivation to tensions that exist when connecting individuals in geographically disparate locations. Using principles from action research, this study is carried out in partnership with the Mapping Across Borders Society, a non-profit group operating in British Columbia, Canada. This study uses semi-structured interviews and thematic coding of emergent themes from interviews with students and professors of Canadian post-secondary institutions and with staff members from African non-governmental organizations. Our findings indicate that there are a wide range of tensions that occur when combining Web 2.0 technologies and online volunteering, that need to be understood to ensure effective online partnerships.
title: Investigating the impact of bio-oil components in esterification upgrading
Creators: name: Bonatti, Erika
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: bio-oil
subject: esterification
subject: upgrading
subject: solid acid catalysts
subject: adsorption
subject: Education--Sciences
subject: Engineering--Chemical
subject: Engineering--Environmental

description: Bio-oil, an organic liquid derived from biomass pyrolysis, shows promise as a sustainable fuel but faces limitations due to its low energy density, corrosiveness, and low stability. Upgrading technologies to improve bio-oil properties exist, but the impact of its constituents during these processes is not well understood. Hence, this study evaluates the impact of phenol and furfural on the performance of solid acid catalysts during acetic acid and methanol esterification. The acid conversion over three different catalysts was examined. Phenol effect on esterification over Amberlyst-15 was evaluated in detail, including kinetic studies and catalyst structural modifications. The presence of phenol led to a decrease in catalyst performance due to their adsorption on the same sites as acetic acid over the Amberlyst-15 structure. The work emphasized how phenol and other bio-oil components could inhibit solid acid catalysts during bio-oil upgrading, offering valuable insights for the upgrading processes.
How UK health care professionals conceptualise parental experiences of the diagnostic process for autism spectrum disorder: A qualitative study.
Creators: name: Daniels, Natasha Faye
name: Coughlan, Barry
name: Duschinsky, Robbie
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Autism Spectrum Disorder
Parental Experience
Diagnostic Pathway

description: ObjectivesMuch of the literature on diagnostic experiences of autism focuses on parental perspectives. Few studies have explored how health care professionals conceptualise parental experiences of the diagnostic process. The current study examines clinical perspectives of the diagnostic process with a focus on the perceived impact of assessment on families.MethodsQualitative interviews were conducted with 25 health care professionals from various National Health Service child and adolescent mental health services and general practices in the United Kingdom. Interviews were transcribed verbatim and data were analysed using a thematic approach.ResultsTwo main themes were identified: (1) stress and the autism spectrum disorder diagnostic process and (2) expectations of the diagnostic pathway. The main sources of stress perceived by the health care professionals related to diagnostic delay and ambiguity around the diagnostic process, with parents facing significant hurdles in understanding their child's behaviour. Many health care professionals also reported a struggle to navigate differing expectations of the diagnostic process between parents and clinicians, as well as managing objectivity in the face of significant distress. Parent internalised stigma and guilt was a key component of the health care professional's perception of sources of stress around the diagnostic process.ConclusionThe vast majority of clinicians recognised the diagnostic pathway as a significant source of stress for parents, with many hurdles and battles to finalise the process.
Hexagon remainder function in the limit of self-crossing up to three loops
Creators: name: Dorn, Harald
name: Wuttke, Sebastian
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider Wilson loops in planar N=4 SYM for null polygons in the limit of two crossing edges. The analysis is based on a renormalisation group technique. We show that the previously obtained result for the leading and next-leading divergent term of the two loop hexagon remainder is in full agreement with the appropriate continuation of the exact analytic formula for this quantity. Furthermore, we determine the coefficients of the leading and next-leading singularity for the three loop remainder function for null n-gons with n >= 6.
description: 19 pages, 4 figures, typos corrected, comment on relation to recent results for the symbol of three-loop remainder added, version to appear in JHEP
Ending preventable maternal mortality: phase II of a multi-step process to develop a monitoring framework, 2016–2030
Creators: name: Jolivet, R. R.
name: Moran, Allisyn C.
name: O’Connor, Meaghan
name: Chou, Doris
name: Bhardwaj, Neelam
name: Newby, Holly
name: Requejo, Jennifer
name: Schaaf, Marta L.
name: Say, Lale
name: Langer, Ana
Publisher: name: Columbia University
Year: 2018
Subjects: Mothers--Mortality--Prevention
Mothers--Health and hygiene
Health status indicators
Health--Social aspects

description: Background
                In February 2015, the World Health Organization (WHO) released “Strategies toward ending preventable maternal mortality (EPMM)” (EPMM Strategies), a direction-setting report outlining global targets and strategies for reducing maternal mortality in the Sustainable Development Goal (SDG) period. In May 2015, the EPMM Working Group outlined a plan to develop a comprehensive monitoring framework to track progress toward the achievement of these targets and priorities. This monitoring framework was developed in two phases. Phase I, which focused on identifying indicators related to the proximal causes of maternal mortality, was completed in October 2015. This paper describes the process and results of Phase II, which was completed in November 2016 and aimed to build consensus on a set of indicators that capture information on the social, political, and economic determinants of maternal health and mortality.

                Findings
                A total of 150 experts from more than 78 organizations worldwide participated in this second phase of the process to develop a comprehensive monitoring framework for EPMM. The experts considered a total of 118 indicators grouped into the 11 key themes outlined in the EPMM report, ultimately reaching consensus on a set of 25 indicators, five equity stratifiers, and one transparency stratifier.

                Conclusion
                The indicators identified in Phase II will be used along with the Phase I indicators to monitor progress towards ending preventable maternal deaths. Together, they provide a means for monitoring not only the essential clinical interventions needed to save lives but also the equally important political, social, economic and health system determinants of maternal health and survival. These distal factors are essential to creating the enabling environment and high-performing health systems needed to ensure high-quality clinical care at the point of service for every woman, her fetus and newborn. They complement and support other monitoring efforts, in particular the “Survive, Thrive, and Transform” agenda laid out by the Global Strategy for Women’s, Children’s and Adolescents’ Health (2016-2030) and the SDG3 global target on maternal mortality.
Incorporation of nanogels within calcite single crystals for the storage, protection and controlled release of active compounds.
Creators: name: Nahi, Ouassef
name: Kulak, Alexander N
name: Kress, Thomas
name: Kim, Yi-Yeoun
name: Grendal, Ola G
name: Duer, Melinda J
name: Cayre, Olivier J
name: Meldrum, Fiona C
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021

description: Nanocarriers have tremendous potential for the encapsulation, storage and delivery of active compounds. However, current formulations often employ open structures that achieve efficient loading of active agents, but that suffer undesired leakage and instability of the payloads over time. Here, a straightforward strategy that overcomes these issues is presented, in which protein nanogels are encapsulated within single crystals of calcite (CaCO3). Demonstrating our approach with bovine serum albumin (BSA) nanogels loaded with (bio)active compounds, including doxorubicin (a chemotherapeutic drug) and lysozyme (an antibacterial enzyme), we show that these nanogels can be occluded within calcite host crystals at levels of up to 45 vol%. Encapsulated within the dense mineral, the active compounds are stable against harsh conditions such as high temperature and pH, and controlled release can be triggered by a simple reduction of the pH. Comparisons with analogous systems - amorphous calcium carbonate, mesoporous vaterite (CaCO3) polycrystals, and calcite crystals containing polymer vesicles - demonstrate the superior encapsulation performance of the nanogel/calcite system. This opens the door to encapsulating a broad range of existing nanocarrier systems within single crystal hosts for the efficient storage, transport and controlled release of various active guest species.
title: The Whole Being Greater than the Sum of its Parts; Exploring the Potential of the Play-within-a-play through the Creation of the Musical The Book of Joan
Creators: name: Tilly, Grant Stephan
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Theatre
subject: Musical
subject: Play-within-a-play
subject: The Book of Job
subject: Adaptation
subject: Theatre for Social Change
subject: Fine Arts
subject: Theater
subject: Music

description: The following dramatic text and artist statement investigates the use of the theatrical convention of the play-within-a-play in the process of research, development, and creation of the musical The Book of Joan. The focus of this paper is on how the interplay between the inner play (a secondary, internal performance) and the outer play (the more extensive narrative within which the inner play exists) might be used to strengthen both narratives and reduce the length of the overall piece. Research was first conducted through the creation of a pre-thesis musical, Susan’s Dream Date, which revealed the importance of self reflection in the creative process and led to a near sung-through aesthetic inspired by the dream/abstract nature of the piece. Through the development of the thesis piece, research took place into the importance of the choice of protagonist, Social Justice Theatre, and Linda Hutcheon’s theory of adaptation in the context of adapting the text of The Book of Job. Through the creation of The Book of Joan, it became evident that utilizing the play-within-a-play convention (especially when developing both the inner and outer narratives simultaneously) enhanced the piece. The metatheatrical interaction between the narratives helped shorten the overall length, making “the whole greater than the sum of its parts.” This research may be a resource for artists using the play-within-a-play convention, musical theatre writers, and those interested in Theatre for Social Change.
Quantum state transfer through a spin chain in a multi-excitation subspace
Creators: name: Wang, Zhao-Ming
name: Ma, Rui-Song
name: Bishop, C. Allen
name: Gu, Yong-Jian
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We investigate the quality of quantum state transfer through a uniformly coupled antiferromagnetic spin chain in a multi-excitation subspace. The fidelity of state transfer using multi-excitation channels is found to compare well with communication protocols based on the ground state of a spin chain with ferromagnetic interactions. Our numerical results support the conjecture that the fidelity of state transfer through a multi-excitation subspace only depends on the number of initial excitations present in the chain and is independent of the excitation ordering. Based on these results, we describe a communication scheme which requires little effort for preparation.
description: 5 pages, 4 figures
Additional file 1 of Functional MRI radiomics-based assessment of pelvic bone marrow changes after concurrent chemoradiotherapy for cervical cancer
Creators: name: Qin, Xiaohang
name: Wang, Cong
name: Gong, Guanzhong
name: Wang, Lizhen
name: Su, Ya
name: Yin, Yong
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Hematology

description: Additional file 1: Supplementary Table 1. Imaging parameters for MRI protocol.
Chrysocyon Smith 1839
Creators: name: Dietz, J. M.
Publisher: name: Zenodo
Year: 1985
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Carnivora
Canidae
Chrysocyon

description: Chrysocyon Smith, 1839
 Chrysocyon Smith, 18391241.
 Type species Canis jubatus Desmarest by original designation.
 CONTEXT AND CONTENT. Order Carnivora, Family Canidae. The genus Chrysocyon contains one species: C. brachyurus (Van Gelder, 1978).
description: Published as part of Dietz, J. M., 1985, Chrysocyon brachyurus, pp. 230704 in Mammalian Species 234 (10) on page 1, DOI: 10.2307/3503796, http://zenodo.org/record/10127812
Family Gauge Bosons with an Inverted Mass Hierarchy
Creators: name: Koide, Yoshio
name: Yamashita, Toshifumi
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A model that gives family gauge bosons with an inverted mass hierarchy is proposed, stimulated by Sumino's cancellation mechanism for the QED radiative correction to the charged lepton masses. The Sumino mechanism cannot straightforwardly be applied to SUSY models because of the non-renormalization theorem. In this paper, an alternative model which is applicable to a SUSY model is proposed. It is essential that family gauge boson masses $m(A_i^j)$ in this model is given by an inverted mass hierarchy $m(A_i^i) \propto 1/\sqrt{m_{ei}}$, in contrast to $m(A_i^i) \propto \sqrt{m_{ei}}$ in the original Sumino model. Phenomenological meaning of the model is also nvestigated. In particular, we notice a deviation from the $e$-$μ$ universality in the tau decays.
description: 13 pages, 1 fugure, added discussion on the neutrino sector, version accepted by Phys.Lett.B
title: Therapeutic Cuddling in Critically Ill Kids: THE ChICKs Studies
Creators: name: Lee, Laurie A
Publisher: name: Cumming School of Medicine
Year: 2024
Subjects: subject: Epidemiology

description: Pain, agitation, delirium, and analgosedation exposure, consequences of pediatric critical illness, are associated with negative sequelae including increased mortality, length of stay, anxiety, post-traumatic stress disorder, impaired neuro-cognitive development, and reduced health-related quality of life, among others. Therapeutic cuddling is a potential intervention to address pediatric intensive care unit (PICU) pain, agitation, delirium, and analgosedation exposure. It involves physical contact such as cuddling, snuggling, or hugging, between a caregiver and child. Despite evidence of benefit in critically ill neonates and hospitalized and healthy children, there is a paucity of literature in critically ill children. The aim of this dissertation was to understand the current state of PICU pain, agitation, and sedation, and inform the development and evaluation of therapeutic cuddling as a potential intervention to address these consequences of pediatric critical illness. To achieve this, theory and methodology from implementation science, knowledge translation, and epidemiology were employed. In the first manuscript, we conducted a systematic review of the prevalence of pain, agitation, and sedation in PICUs. We found variability in measurement, conceptualization, and reporting, with prevalence estimates of 45-82% for pain, 2-42% for agitation, and 9-62% for oversedation. The second manuscript is a secondary analysis of five point-prevalence studies on early acute rehabilitation (PARK-PICU studies) aimed at describing the prevalence of therapeutic cuddling and potential safety events in PICUs from North America, South America, Europe, and Australasia. Multilevel multivariable logistic regression identified patient-level variables associated with therapeutic cuddling. The prevalence of therapeutic cuddling was 37.4%, and the prevalence of potential safety events was 2.8%. The third manuscript is a mixed methods cross-sectional survey based on the Theoretical Domains Framework administered to healthcare professionals in Canadian PICUs aimed at understanding important barriers and facilitators to therapeutic cuddling. Identified barriers included beliefs about risk and safety, staffing, and lack of prioritization of therapeutic cuddling. The most important facilitator was family participation. The results of these three manuscripts address knowledge gaps related to the prevalence of pain, agitation, and sedation and the current state of therapeutic cuddling in critically ill children. Together these provide a foundation for the development and evaluation of therapeutic cuddling as a potential intervention to address PICU pain, agitation, and analgosedation exposure.
Aspiration versus peritoneal lavage in appendicitis: a meta-analysis
Creators: name: Burini, Gloria
name: Cianci, Maria Chiara
name: Coccetta, Marco
name: Spizzirri, Alessandro
name: Di Saverio, Salomone
name: Coletta, Riccardo
name: Sapienza, Paolo
name: Mingoli, Andrea
name: Cirocchi, Roberto
name: Morabito, Antonino
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Review
Complicated appendicitis
Post-operative intra-abdominal abscess
Peritoneal irrigation
Abscess suction

description: Abstract: Background: Acute appendicitis is one of the most frequent abdominal surgical emergencies. Intra-abdominal abscess is a frequent post-operative complication. The aim of this meta-analysis was to compare peritoneal irrigation and suction versus suction only when performing appendectomy for complicated appendicitis. Methods: According to PRISMA guidelines, a systematic review was conducted and registered into the Prospero register (CRD42020186848). The risk of bias was defined to be from low to moderate. Results: Seventeen studies (9 RCTs and 8 CCTs) were selected, including 5315 patients. There was no statistical significance in post-operative intra-abdominal abscess in open (RR 1.27, 95% CI 0.75–2.15; I2 = 74%) and laparoscopic group (RR 1.51, 95% CI 0.73–3.13; I2 = 83%). No statistical significance in reoperation rate in open (RR 1.27, 95% CI 0.04–2.49; I2 = 18%) and laparoscopic group (RR 1.42, 95% CI 0.64–2.49; I2 = 18%). In both open and laparoscopic groups, operative time was lower in the suction group (RR 7.13, 95% CI 3.14–11.12); no statistical significance was found for hospital stay (MD − 0.39, 95% CI − 1.07 to 0.30; I2 = 91%) and the rate of wound infection (MD 1.16, 95% CI 0.56–2.38; I2 = 71%). Conclusions: This systematic review has failed to demonstrate the statistical superiority of employing intra-operative peritoneal irrigation and suction over suction-only to reduce the rate of post-operative complications after appendectomy, but all the articles report clinical superiority in terms of post-operative abscess, wound infection and operative times in suction-only group.
Some reflexions on the Riemst- Caestert Iron age fortification part 1
Creators: name: Groen, Jimmy
Publisher: name: Zenodo
Year: 2014
Subjects: Caestert, Fortification, Iron Age, Roman

description: The Iron Age fortification at Visé - Caestert / Riemst Caster in Belgium shows a lack of finds from the surface. This though metal detecting took place, and hardly any shard has been found at the surface, contrary to Iron age fortifications like at Bourguignon (F). This short paper discusses the possibility of leveling activities by Roman soldiers and other disturbance that lead to this situation.
MATLAB-based general approach for square-root extended-unscented and fifth-degree cubature Kalman filtering methods
Creators: name: Kulikova, Maria V.
name: Kulikov, Gennady Yu.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Optimization and Control (math.OC)
subject: FOS: Mathematics

description: A stable square-root approach has been recently proposed for the unscented Kalman filter (UKF) and fifth-degree cubature Kalman filter (5D-CKF) as well as for the mixed-type methods consisting of the extended Kalman filter (EKF) time update and the UKF/5D-CKF measurement update steps. The mixed-type estimators provide a good balance in trading between estimation accuracy and computational demand because of the EKF moment differential equations involved. The key benefit is a consolidation of reliable state mean and error covariance propagation by using delicate discretization error control while solving the EKF moment differential equations and an accurate measurement update according to the advanced UKF and/or 5D-CKF filtering strategies. Meanwhile the drawback of the previously proposed estimators is an utilization of sophisticated numerical integration scheme with the built-in discretization error control that is, in fact, a complicated and computationally costly tool. In contrast, we design here the mixed-type methods that keep the same estimation quality but reduce a computational time significantly. The novel estimators elegantly utilize any MATLAB-based numerical integration scheme developed for solving ordinary differential equations (ODEs) with the required accuracy tolerance pre-defined by users. In summary, a simplicity of the suggested estimators, their numerical robustness with respect to roundoff due to the square-root form utilized as well as their estimation accuracy due to the MATLAB ODEs solvers with discretization error control involved are the attractive features of the novel estimators. The numerical experiments are provided for illustrating a performance of the suggested methods in comparison with the existing ones.
Circulating extracellular vesicles during pregnancy in women with type 1 diabetes: a secondary analysis of the CONCEPTT trial
Creators: name: Abolbaghaei, Akram
name: Langlois, Marc-André
name: Murphy, Helen R
name: Feig, Denice S.
name: Burger, Dylan
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Research
Extracellular vesicle
Type 1 diabetes
Pregnancy
Endothelial
Platelet
Microparticle
Microvesicle
Biomarker

description: Abstract: Background: Extracellular vesicles are membrane vesicles that are released into the extracellular environment and accumulate in the circulation in vascular disease. We aimed to quantify circulating extracellular vesicles in pregnant women with type 1 diabetes and to examine associations between extracellular vesicle levels, continuous glucose measures, and pregnancy outcomes. Methods: We used plasma samples from the Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial study and quantified circulating extracellular vesicles by flow cytometry (n = 163). Relationships with clinical variables were assessed by repeated measures correlation. Logistic regression was used to assess associations between elevated extracellular vesicle levels and pregnancy outcomes. Results: Platelet extracellular vesicle levels were inversely associated with glucose time above range and glycaemic variability measures (P < 0.05). A weak positive association was observed between endothelial extracellular vesicles and mean amplitude of glycemic excursion (P < 0.05). In a univariate logistic regression model, high baseline endothelial extracellular vesicles was associated with increased risk of neonatal intensive care unit (NICU) admission (OR: 2.06, 1.03–4.10), and respiratory distress requiring ventilation (OR: 4.98, 1.04–23.92). After adjusting for HbA1c and blood pressure the relationship for NICU admission persisted and an association with hyperbilirubinemia was seen (OR: 2.56, 1.10–5.94). Elevated platelet extracellular vesicles were associated with an increased risk of NICU admission (OR: 2.18, 1.04–4.57), and hyperbilirubinemia (OR: 2.61, 1.11–6.12) after adjusting for HbA1c and blood pressure. Conclusions: High levels of extracellular vesicles in early pregnancy were associated with adverse neonatal outcomes. Assessment of extracellular vesicles may represent a novel approach to personalized care in type 1 diabetes pregnancy.
mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development
Creators: name: Nie, Xuguang
name: Zheng, Jinxuan
name: He, Ling
name: Jiao, Kai
name: Mao, Jeremy J.
name: Ricupero, Christopher L.
Publisher: name: Columbia University
Year: 2018
Subjects: Genetics—Research
Embryology
Morphogenesis
Protein kinases--Physiological effect
Skull--Abnormalities

description: mTOR is a highly conserved serine/threonine protein kinase that is critical for diverse cellular processes in both developmental and physiological settings. mTOR interacts with a set of molecules including Raptor and Rictor to form two distinct functional complexes, namely the mTORC1 and mTORC2. Here, we used novel genetic models to investigate functions of the mTOR pathway for cranial neural crest cells (NCCs), which are a temporary type of cells arising from the ectoderm layer and migrate to the pharyngeal arches participating craniofacial development. mTOR deletion elicited a proliferation deficit and excessive apoptosis of post-migratory NCCs, leading to growth arrest of the facial primordia along with midline orofacial clefts. Furthermore, NCC differentiation was impaired. Thus, NCC derivatives, such as skeletons, vasculatures and neural tissues were either rudimentary or malformed. We further demonstrate that disruption of mTOR caused P53 hyperactivity and cell cycle arrest in cranial NCCs, and lowering P53 activity by one copy reduction attenuated the severity of craniofacial phenotype in NCC-mTOR knockout mice. Remarkably, NCC-Rptor disruption caused a spectrum of defects mirroring that of the NCC-mTOR deletion, whereas NCC-Rictor disruption only caused a mild craniofacial phenotype compared to the mTOR and Rptor conditional knockout models. Altogether, our data demonstrate that mTOR functions mediated by mTORC1 are indispensable for multiple processes of NCC development including proliferation, survival, and differentiation during craniofacial morphogenesis and organogenesis, and P53 hyperactivity in part accounts for the defective craniofacial development in NCC-mTOR knockout mice.
Automatic dispenser of live Black Soldier Fly larvae to feed poultry
Creators: name: Dörper, A.
name: Gort, G.
name: Veldkamp, T.
name: Dicke, M.
Publisher: name: Brill Online
Year: 2023
Subjects: classificationCode: 309999
subject: Other agricultural, veterinary and food sciences not elsewhere classified

description: Feeding poultry with live insect larvae stimulates natural behaviour and improves poultry welfare, when poultry has prolonged or frequent access to the larvae. But how to feed live insect larvae to poultry without labour-intensive hand feeding? This paper focusses on the development of a device that overcomes this challenge. A circular device was designed with eight storage compartments, which were filled once a day with live Black Soldier Fly (BSF) larvae (Hermetia illucens). A motor controlled the timed rotation of the device multiple times per day, initiating the release of larvae when a compartment was pushed over an outlet. Every 60 minutes, a new compartment was pushed over the outlet, which means that after eight hours all compartments are emptied. To achieve a gradual release of larvae per storage compartment the device was timed to move every 30 minutes half a storage compartment forward. The larval release was recorded every 5 minutes within the 60 minutes. The device was tested at 18 ℃, 24 ℃ and 30 ℃, with 3.4 g and 129.8 g BSF larvae per compartment, and with three different outlet types of different size and shape. The larval release rate was influenced by temperature, amount of larvae, outlet type, and interactions between these factors. After placing a new compartment above the outlet, 50% of the larvae were on average released within 6 minutes. After 60 minutes, on average only 0.5% larvae remained in the compartment. Outlets with wider openings are preferred over the outlet with the narrowest outlet because less larvae remained in the compartments. The dispenser fulfilled the low-labour-intensity requirement as filling was only necessary once a day, the release of different amounts of larvae was achieved over several hours. This automatic dispenser provides a valuable tool to investigate the behaviour of poultry fed with live BSF larvae.
Extra Matters Decree the Relatively Heavy Higgs of Mass about 125 GeV in the Supersymmetric Model
Creators: name: Moroi, Takeo
name: Sato, Ryosuke
name: Yanagida, Tsutomu T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We show that the Higgs mass about 125 GeV is easily realized in supersymmetric model with extra matters, simultaneously explaining the anomaly in the muon anomalous magnetic moment and the dark matter density.
description: 10 pages, 2 figures; V2: version accepted for publication of PLB