cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Anisotine and amarogentin as promising inhibitory candidates against SARS-CoV-2 proteins: a computational investigation
Creators: name: Kar, Pallab
name: Kumar, Vijay
name: Vellingiri, Balachandar
name: Sen, Arnab
name: Jaishee, Nishika
name: Anandraj, Akash
name: Malhotra, Himani
name: Bhattacharyya, Subires
name: Mukhopadhyay, Subhasish
name: Kinoshita, Masako
name: Govindasamy, Vivekanandhan
name: Roy, Ayan
name: Naidoo, Devashan
name: Subramaniam, Mohana Devi
Publisher: name: Mangosuthu University of Technology (MUT)
Year: 2022
Subjects: classificationCode: 300101
subject: Agricultural biotechnology diagnostics (incl. biosensors)
classificationCode: 320699
subject: Medical biotechnology not elsewhere classified

description: The coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syn?drome coronavirus 2 (SARS-CoV-2), presents an unprecedented challenge to global public health with
researchers striving to find a possible therapeutic candidate that could limit the spread of the virus. In
this context, the present study employed an in silico molecular interaction-based approach to estimate
the inhibitory potential of the phytochemicals from ethnomedicinally relevant Indian plants including
Justicia adhatoda, Ocimum sanctum and Swertia chirata, with reported antiviral activities against crucial
SARS-CoV-2 proteins. SARS-CoV-2 proteins associated with host attachment and viral replication
namely, spike protein, main protease enzyme Mpro and RNA-dependent RNA polymerase (RdRp) are
promising druggable targets for COVID-19 therapeutic research. Extensive molecular docking of the
phytocompounds at the binding pockets of the viral proteins revealed their promising inhibitory
potential. Subsequent assessment of physicochemical features and potential toxicity of the compounds
followed by robust molecular dynamics simulations and analysis of MM-PBSA energy scoring function
revealed anisotine against SARS-CoV-2 spike and Mpro proteins and amarogentin against SARS-CoV-2
RdRp as potential inhibitors. It was interesting to note that these compounds displayed significantly
higher binding energy scores against the respective SARS-CoV-2 proteins compared to the relevant
drugs that are currently being targeted against them. Present research findings confer scopes to
explore further the potential of these compounds in vitro and in vivo towards deployment as efficient
SARS-CoV-2 inhibitors and development of novel effective therapeutics.
Algorithmic and interpretive moves in identifying NGI Forward key topics
Creators: name: Cottica, Alberto
name: Gyódi, Kristóf
name: Nissen, Ida A.
name: Paliński, Michał
Publisher: name: Zenodo
Year: 2021
Subjects: internet, next generation internet, ethnography, data science, text analysis, natural language processing

description: In the course of the final year of the NGI Forward project, three of its partners (DELab and the University of Aarhus, in the course of Work Package 1; and Edgeryders, in that of Wok Package 2) have been working on identifying the overarching issues that kept resurfacing when considering the evolution of Internet technology. That work has been done independently by each partner, but the partners have kept comparing notes. In autumn 2021 it had become clear that our methods, though different, were similar enough for a systematic comparison. We decided to coordinate in writing an extra paper to contain such a comparison. The comparative perspective, we find, brings clarity and accountability to our respective research workflows. This document is that paper. We intend it as an add-on to our work on topic identification in NGI Forward, contained in more detail elsewhere (see the bibliography), as well as a stand-alone paper on the epistemology of doing data science on social phenomena as captured by text data.
Shenandoah Valley Archives at Work: Three Initiatives that Preserve and Share Diverse Regional History
Creators: name: Gardner, Stephanie
name: Baugher, Taylor
name: Imerson, Penny
name: Brinkerhoff, Tyler
name: Hottel, Zachary
name: Kawecki, Eryn
Publisher: name: Digital Repository at the University of Maryland
Year: 2022

description: The Shenandoah Valley of Virginia is filled with a number of small community and academic archives that work to preserve the rich history of a unique region. While these institutions are small, their work is mighty. Valley archives and their staff conduct numerous creative projects that combine best practices, a commitment to the community they serve, and a dedication to diverse voices. This session will feature a profile of three small archives from the Shenandoah Valley and three projects that launched to better serve the needs of their community. The institutions and the projects they will discuss are: • Bridgewater College Special Collections and the 2021 exhibit “State of Change: Civil Rights and the Virginia Constitution” that used primary sources to engage viewers with both local and state Black history. • Rocktown History and the project “Shape Note Traditions of the Shenandoah Valley” which reunited scattered musical collections from small archives throughout the Shenandoah Valley into a new, more accessible, digital format. • Shenandoah County Library’s Truban Archives and the “Bondage Biographies Project” which works to document the lives of enslaved persons in Shenandoah County through an online database.
Que perspectivas para a economia portuguesa no quadro da união económica e monetária?
Creators: name: Pintado, Valentim Xavier
Publisher: name: Gestão e Desenvolvimento
Year: 1994

description: O Mercado Único Europeu, de que fazemos parte, tem vindo a remover os obstáculos à livre circulação de mercadorias, pessoas, serviços e capitais e à liberdade de estabelecimento de empresas de outros países membros, com vista a realizar um mercado europeu integrado, como se fora o de um único país. Entretanto, a União Monetária visa chegar a uma moeda única, que reduza os custos de transacção e assegure a transparência dos preços em todo esse vasto mercado. O embarcar num tal projecto constitui uma das decisões de maior alcance e carregada de consequências que um Estado pode tomar no campo económico. Uma coisa é certa, e essa é a conclusão tanto da teoria como a lição da experiência histórica: a abertura dos mercados e o aprofundamento da integração económica é fonte de melhoria de bem estar económico e de criação de riqueza. O que não é certo, nem a teoria económica permite dilucidar, é a forma como se distribui esse acréscimo de bem estar entre países e regiões. A nossa pergunta, hoje, consiste nisto: o que vai suceder à economia portuguesa, ou o que podemos esperar que lhe suceda, ao participar nesse projecto de integração progressiva?
description: Gestão e Desenvolvimento, n. 3 (1994)
Desenvolvimento das actividades competitivas das empresas na área comercial
Creators: name: Nascimento, Fernando
Publisher: name: Gestão e Desenvolvimento
Year: 1994

description: Procurarei dar, no princípio, uma ideia do que é e do que foi a evolução das actividades de Marketing em Portugal que já têm uma longa história. Deixem-me contar duas historietas: uma do mundo da banda desenhada, a outra de conteúdo mais histórico. - A primeira tem a ver com um autor de banda desenhada chamado Hergé, o autor das histórias do TinTin. Ele escreveu 20 e tal livros sobre assuntos passados em muitos países diferentes e inventou centenas de personagens. No meio daquela confusão apareceu lá um português que é o senhor Oliveira da Figueira, um comerciante das sete partidas do mundo. É uma figura simpática, que ajuda o herói dessas aventuras, mas é uma figura dedicada ao comércio. Aparentemente Hergé, que recolheu informação sobre "n" povos do mundo, ao olhar para os portugueses apanhou esta nossa faceta comercial e retratou o povo português através desta figura. Penso que, de certa forma, os Portugueses têm algum jeito inato para o comércio. - A segunda historieta é que nós somos um povo descobridor, em que a actividade comercial representou algo muito importante na nossa História. É evidente que o pico já foi há 500 anos atrás, mas ao longo da História há vários episódios que reforçam esta ideia. Direi que, nessa altura, tínhamos uma visão moderna do comércio internacional (hoje utilizamos a palavra global, que é uma palavra agora muito em moda). E não se pense que o comércio português era só entre a Metrópole e as colónias: onde quer que estivéssemos, encontrávamos oportunidades de fazer negócio, de uma forma extremamente rentável para ambos os lados.
description: Gestão e Desenvolvimento, n. 3 (1994)
Breves notas sobre cultura de qualidade
Creators: name: Raposo, Nicolau Vasconcelos
Publisher: name: Gestão e Desenvolvimento
Year: 1994

description: Cumpre-me, em primeiro lugar, apresentar a V. Ex.a, Senhor Ministro dos Negócios Estrangeiros, as respeitosas saudações do Instituto Universitário de Desenvolvimento e Promoção Social pela sua presença nesta sessão de encerramento das IV Jornadas de Gestão. O Conselho de Direcção do I.U.D.P.S. havia já dirigido convite a V. Ex.ª para proferir uma conferência, no âmbito das actividades do seu Ministério, iniciativa que é possível concretizar hoje. Em seguida, desejaria congratular-me com a realização destas IV Jornadas de Gestão que, durante dois dias, nos reuniram para partilharmos das sessões científicas e dos debates que se lhes seguiram, os quais se revelaram extremamente fecundos. Depois do ciclo de conferências sobre temas económicos, realizado na primeira quinzena de Novembro e promovido pelo Conselho de Direcção do Instituto, as IV Jornadas de Gestão, organizadas pelo Conselho de Delegados da licenciatura em Gestão e Desenvolvimento Social, dão bem uma imagem da vitalidade e do trabalho que vimos realizando e que me apraz realçar.
description: Gestão e Desenvolvimento, n. 3 (1994)
Program for the Spring 2022 MARAC Meeting: Communities Big and Small
Creators: name: MARAC: Mid-Atlantic Regional Archives Conference
Publisher: name: Digital Repository at the University of Maryland
Year: 2022
Subjects: MARAC
Mid-Atlantic Regional Archives Conference
Harrisonburg
Virginia

description: The program for the Spring 2022 MARAC meeting, "Communities Big and Small" held April 24-26 in Harrisonburg, VA.
Contribuição da estratégia da produção para a estratégia do negócio
Creators: name: Silva, J. M. Vilas-Boas Da
Publisher: name: Gestão e Desenvolvimento
Year: 1994

description: A estratégia da produção é um elo fundamental da estratégia empresarial que nem sempre tem sido objecto da atenção que merece. Este artigo pretende chamar a atenção para esta realidade, analisar algumas das lacunas existentes e promover a divulgação de uma metodologia de abordagem do tema, com cariz prático.
description: Gestão e Desenvolvimento, n. 3 (1994)
Carnet nº 20, commencé à Canton (p. 9)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: created: 1-5-1931
Additional file 16 of Efficacy and safety of various primary treatment strategies for very early and early hepatocellular carcinoma: a network meta-analysis
Creators: name: Yang, Sha
name: Lin, Huapeng
name: Song, Jianning
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Biotechnology
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 15: Table S1. The inconsistent loops P-value for different comparisons.
A cultura organizacional e o(s) podere(s) da história na estruturação da identidade da empresa
Creators: name: Amaro, António Rafael
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: O pior contributo - seja em que perspectiva for- que neste momento se pode dar ao debate sobre a vertente cultural das organizações é escamotear a sua dimensão ideológica e considerar a emergência da cultura de empresa como neutra. Será talvez útil recordar que esta não é a primeira vez, nem por certo a última, que as teorias sobre as organizações recorrem a metáforas como modelos de compreensão e explicação. Se as teorias, hoje emergentes, se socorrem da metáfora cultural - considerando, portanto, as organizações culturas -, já anteriormente o mesmo se verificou com outras teorias que viam as empresas, como refere Jorge Vala, «metaforicamente ora como máquinas (lembremos os primeiros estudos no interior do paradigma da organização científica do trabalho), ora como organismos (metáfora subjacente às teorias sistémicas sobre as organizações), ora como cérebros (teorias da decisão e do processamento da informação aplicadas às organizações), etc.» (J. Vala et al.,1988: 663).
description: Gestão e Desenvolvimento, n. 2 (1993)
Marketing, estratégia e identidade de empresa ("Mercator" e "Strategor")
Creators: name: Mendes, José M. Amado
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: • Jacques Lendrevie, Denis Lindon, Pedro Dionísio e Vicente Rodrigues, MERCATOR: Teoria e prática do marketing, col. «Gestão & Inovação», série «Ciências de Gestão», 1, 2.ª ed., Lisboa, Publ. Dom Quixote, 1992, 516+XLVIII p. • Jean-Pierre Anastassopoulos et al., Estratégia. Estrutura. Decisão. Identidade. STRATEGOR: Política global de empresa (trad. do francês), col. «Gestão & Inovação», série «Ciências de Gestão», 2, Lisboa, Publ. Dom Quixote, 1993, 441 p.
description: Gestão e Desenvolvimento, n. 2 (1993)
José M. Amado Mendes (Col. Manuel Ferreira Rodrigues), Santos Barosa - 100 anos no vidro, 1889-1981, Marinha Grande, Santos Barosa - Vidros, S. A., 1992, 232 pp. (com ilustração)
Creators: name: Amaro, António Rafael
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: Gestão e Desenvolvimento, n. 2 (1993)
title: Bernardine Healy, Jacques Leibowitch (trad.), "Pas de conspiration dans la découverte du virus HIV"
Creators: name: Healy, Bernardine
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Article paru dans le Chicago Herald Tribune du 10 Janvier 1995.
description: Source: http://www.calames.abes.fr/pub/ms/Calames-20193111031798183
description: created: start=1975;end=2018
70 years of herpetology in India: insights into shifts in focal research areas and gender ratios among authors
Creators: name: Cyriac, Vivek Philip
name: Dharwardkar, Sneha
name: Mital, Anuja
name: Mohan, Ashwini Venkatanarayana
Publisher: name: Brill Online
Year: 2022
Subjects: Ecology not elsewhere classified

description: Herpetology in India started as a science during the British colonial rule with the documentation of herpetofauna. Several studies have outlined the early history of Indian herpetology; however, few have traced the growth of this field since India’s independence. We analyse trends in Indian herpetology focusing on taxa, subfields, and authorship over the last 70 years. Of the 1177 published articles we analysed, 64.9% studied reptiles, 26.5% studied amphibians and 8.6% were general herpetofaunal studies. Frogs, lizards, and snakes being the most diverse herpetofauna groups, each accounted for 20-21% of the published articles and significantly outnumber publications on caecilians (2.3%), salamanders (0.4%), chelonians (12.6%), and crocodiles (4.4%). We found a significantly greater number of publications on Diversity & Distribution (34.2%), Taxonomy & Systematics (21.5%) and Ecology (19.2%) compared to other subfields, and detected a decline in Development, Physiology & Cytology and Evolutionary biology studies over the last four decades (1980-2019). The gender ratio among co-authors was dominated by men with only 29.7% of publications containing women authors. The overall proportion of women authors has not changed significantly over decades, but our analyses detected a significant decrease in women first authors and the proportion of women authors when the corresponding authors were men. Women authors were substantially lower in the subfield of Taxonomy & Systematics, and women published significantly more on amphibians compared to reptiles. Overall, we highlight the growth of herpetology in India from two key viewpoints, scientific pursuits, and gender parity among herpetologists.
The Kinematics of the Outer Galactic Disk from A and F Stars
Creators: name: Harris, Amy
Publisher: name: UH Research Archive
Year: 2019
Subjects: Astronomy
Astrophysics
Kinematics
Stars
Milky Way
Galaxy
galactic disk
rotation curve
young stars
massive stars
F stars
A stars
Dynamics
outer disk
Gaia
proper motion
radial velocity
spectroscopy

description: The kinematics of stars in the outer Galactic disk is poorly known. In addition to constraining the Galactic potential, knowledge of the motions of stars throughout the disk facilitates studies of non-axisymmetric motion, such as streaming motions due to spiral arms. Understanding the kinematics of the disk in full, including the rotation law, will help to map out its structure, and set constraints on its formation and evolution. I explore the kinematics of A/F stars in two outer-disk pencil beams. I show that A stars in particular are useful probes of outer Galactic disk kinematics. The use of these relatively early-type stars is an alternative to the ISM gas tracers and clump giants that have been commonly used in previous studies. A/F stars offer the advantage of reduced kinematic scatter and asymmetric drift as compared to the older clump giants, and can provide a much denser sampling in the outer disk than ISM gas tracers. They are bright so can be detected out to great distances, and large samples can be efficiently selected from the IPHAS r-i, r-Hα plane. The sightlines were chosen to sample the strong shear in Galactic rotation (ℓ= 118˚), and as a control (ℓ= 178˚). Radial velocities (RVs) and extinction-corrected spectro-photometric distances are computed for the sample of >1300 A/F stars with the aid of MCMC parameter fitting. The rotation law measured at ℓ=118˚ using the RV data is sharply rising out from RG ~11 kpc, going against expectations of a flat or slowly rising law. Gaia DR2 astrometry, released in April 2018, provided proper motions for the sample. On combining these with the measured RVs and spectro-photometric distances, full space motions are obtained. The Galactocentric radial, azimuthal, and vertical velocity trends are constructed without any prior assumption about the velocity field. The measured rotation curve incorporating proper motion data is flat at ℓ = 178˚, but remains sharply rising at ℓ = 118˚, albeit less so than that determined using only RV data. I consider the detailed form of the observed Galactocentric trends with specific perturbers in mind, finding no clear interpretation in terms of perturbation from the central bar or spiral arms. The variation of observed trends with longitude and distance is a reflection of the complex dynamics in our Galaxy. The methods developed in this work and the use of A stars as tracers will be used in the future for fuller exploitation via spectroscopy on forthcoming massively multiplexed wide-field spectrographs. In particular, the PTMCMC method presented will be used to analyse WEAVE survey products. Future use of these young stellar tracers will help us to understand how our Galaxy is, and came to be, how it is now.
Influxos da transformação do «status» e do papel da mulher sobre a natalidade
Creators: name: Dias, Maria Olívia
Publisher: name: Gestão e Desenvolvimento
Year: 1992

description: Não existe conduta sem motivação, mas para que haja motivação é necessário que o estímulo externo solicite o espírito para que este se possa pôr em acção. Isto sucede também em relação ao tema do nosso trabalho: OS INFLUXOS DA TRANSFORMAÇÃO DO «STATUS» E DO PAPEL DA MULHER SOBRE A NATALIDADE. Portanto, dentro dos nossos limites, a finalidade do nosso trabalho é ver se e como a nova condição da mulher incide sobre um dos principais aspectos da dinâmica demográfica: a natalidade. Além disso procuramos descobrir quais são os principais factores que provocam tal mudança. Tudo isto tendo em atenção a diversidade de população, que certamente se reflecte numa diferença dos comportamentos demográficos em geral, e nos comportamentos procriativos em particular.
description: Gestão e Desenvolvimento, n. 1 (1992)
O cristão entre o evangelho e a concorrência
Creators: name: Monteiro, António
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: O homem, seja ele quem for, no dizer bem conhecido de Ortega Y Gasset, é sempre e necessariamente o homem e a sua circunstância. É a questão importante, da interacção radical entre o homem e o seu ambiente. Num mundo invadido pela concorrência, frequentemente desenfreada, tal contexto mexe necessariamente com todo e qualquer homem e, muito em especial, com os seus comportamentos. Sucede isso também com o cristão, muito embora ele tenha o evangelho como o grande ideal e programa de base na sua vida. A influência de um tal contexto ambiental converte-se, a partir daí, num problema, por vezes dramático, nomeadamente quando esse contexto revela uma dinâmica em contradição frontal com a dinâmica do evangelho. É o caso certamente da dinâmica concorrencial. Num ambiente assim, o cristão terá por vezes de fazer opções muito sérias, opções daquelas que, na expressão de Kierkegaard, ele tem de afrontar em clima de angústia, de vertigem metafísica, com temor e tremor, armado sempre e só em cavaleiro da fé.
description: Gestão e Desenvolvimento, n. 2 (1993)
Educação e desenvolvimento
Creators: name: Raposo, Nicolau De Almeida Vasconcelos
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: O tema que escolhemos para tratar nesta sessão solene de bênção e de entrega de diplomas de licenciatura intitula-se Educação e desenvolvimento. Contendo inquestionáveis potencialidades de abordagem, comporta, no entanto, o risco da vastidão. Por tal motivo, optámos por analisar três questões essenciais, entre as que seria legítimo abordar no âmbito da temática enunciada. A primeira dessas questões diz respeito às relações entre educação e mobilidade social, nomeadamente em articulação com o problema da desigualdade de oportunidades perante o ensino. O segundo ponto a abordar refere-se às relações entre economia e educação, encaradas a partir da teoria do capital humano. Por último, e tendo em conta a actualidade da temática do desenvolvimento - indissociável do investimento em educação -, analisaremos este conceito na sua perspectiva cristã.
description: Gestão e Desenvolvimento, n. 2 (1993)
Considerações sobre a possibilidade da adesão da comunidade à convenção Europeia dos direitos do homem
Creators: name: Cunha, Luís Pedro
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: À primeira vista pode parecer pouco compreensível que duas ordens jurídicas, resultantes da convenção Europeia dos direitos do homem (CEDH) e da Comunidade Europeia do Carvão e do Aço (CECA), que foram criadas quase simultaneamente e no mesmo contexto regional, a Europa, tenham prescindido, quando da sua implementação, da previsão de um qualquer mecanismo de coordenação entre ambas. É fácil de ver, no entanto, que a criação de um mercado comum do carvão e do aço parecia não interferir, em razão da matéria, com direitos fundamentais. Por outro lado, os Estados vinculados por cada um dos tratados não coincidiam totalmente.
description: Gestão e Desenvolvimento, n. 2 (1993)
O pastoreio em Portugal (subsídios para o seu estudo)
Creators: name: Martinho, Alberto
Publisher: name: Gestão e Desenvolvimento
Year: 1993

description: O pastoreio em Portugal começa a chegar formalmente até nós, sobretudo através das referências inscritas nos forais, cartas régias, alvarás régios, códigos de posturas municipais. Também nalguns estudos históricos se inserem descrições etnográficas que fornecem dados importantes sobre o mesmo tema. No entanto os estudos sistemáticos sobre o tema foram conduzidos, entre outros, por Tude de Sousa, Amorim Girão, Jorge Dias, Orlando Ribeiro, Alberto Martinho. A nível de estudos monográficos aparecem referências várias a este tema que nós citaremos neste trabalho.
description: Gestão e Desenvolvimento, n. 2 (1993)
A global measure of patient-reported outcomes after injury – life back on track
Creators: name: Chen, Gang
name: Woode, Maame Esi
name: Sia, Kah Ling
name: Ellis, Nina
name: Citroen, Cassie
name: Harris, Anthony
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Assess the psychometric properties of the Life Back on Track (LBoT) measure, a novel self-reported single-item global measure of the trajectory of wellbeing after a transport accident. Evaluated the validity, reliability, sensitivity, and responsiveness using four survey waves (n = 1556 in wave 1), and two repeated cross-sectional surveys (n = 5238) and (n = 1964), of individuals injured in a transport accident in Victoria. There were statistically significant differences in the distribution of the LBoT scores by the respondent depression or pain scores, return to work status, financial ability to get by, ability to cope, and ability to bounce back (all p < 0.001). The LBoT measure was a statistically significant (p < 0.001) and reasonable predictor of future work status, and was moderately correlated (>0.67) with the EQ-5D-3L (concurrent validity). Retest reliability (ICC ≥0.76) and sensitivity (effect sizes >1.52) were supported, and it was moderately responsive to change (standard response mean statistics 0.4–0.8). LBoT is a valid measure to track the individual’s trajectory of subjective wellbeing in the context of recovery after a trauma, and is potentially useful as an indicator to track the performance of commissioned providers, and to monitor or evaluate the value of service outcomes.Implications for RehabilitationThere is a demand to develop a simple metric to measure the impact of injury, the effectiveness of rehabilitation and the degree of recovery from trauma.Life Back on Track (LBoT) is a valid single-item measure to track an individual’s trajectory of subjective wellbeing after trauma.It has the potential to complement clinical measures where a routine collection of a simple measure is desirable.It is suitable as an indicator of service outcomes for organisations that commission services. There is a demand to develop a simple metric to measure the impact of injury, the effectiveness of rehabilitation and the degree of recovery from trauma. Life Back on Track (LBoT) is a valid single-item measure to track an individual’s trajectory of subjective wellbeing after trauma. It has the potential to complement clinical measures where a routine collection of a simple measure is desirable. It is suitable as an indicator of service outcomes for organisations that commission services.
A indústria no distrito de Viseu (subsídios para o seu estudo)
Creators: name: Martinho, Alberto
Publisher: name: Gestão e Desenvolvimento
Year: 1992

description: Quando em Outubro de 1988 fomos contactados pelo Presidente da Associação Industrial da Região de Viseu (AIRV)1 para a efectivação de um estudo tendente à caracterização do tecido industrial2, respondemos, desde logo, afirmativamente. Fomos motivados para a realização deste estudo, sobretudo pelas seguintes razões: - A Universidade Católica Portuguesa (Centro Regional de Viseu), através da sua Associação de Apoio ao Instituto Universitário de Desenvolvimento e Promoção Social (A.I.U.D.P.S.) pretende estar à escuta das necessidades dos actores económicos, culturais e sociais da região, de molde a poder ser parceiro na investigação-acção que possa ser levada a cabo. - A Universidade Católica está também interessada na formação integral dos alunos. Por tal, aproveita estas oportunidades para a formação, científica e humana, dos elementos que nela trabalham, quer os docentes, quer os discentes. - Este estudo também deu origem à colaboração com outras instituições que trabalham na área desde o Instituto de Apoio às Pequenas e Médias Empresas e ao Investimento (IAPMEI), Comissão de Coordenação da Região Centro (CCRC), Empresas, Instituições Bancárias, Câmaras Municipais, entre outras.
description: Gestão e Desenvolvimento, n. 1 (1992)
Para um modelo cristão de desenvolvimento
Creators: name: Felício, Manuel Da Rocha
Publisher: name: Gestão e Desenvolvimento
Year: 1992

description: Como introdução ao tratamento do tema do desenvolvimento em sua visão cristã, é oportuna uma justificação prévia da relação legítima e necessária entre Mensagem do Evangelho e promoção humana. Passamos a analisar duas posições extremas, para depois indicar as últimas orientações do pensamento cristão sobre a matéria.
description: Gestão e Desenvolvimento, n. 1 (1992)
Cultura de empresa: uma nova dinâmica organizacional
Creators: name: Mendes, José M. Amado
Publisher: name: Gestão e Desenvolvimento
Year: 1992

description: Nas últimas décadas, o conceito de cultura tem vindo a adquirir um âmbito muito mais vasto que o tradicional. Este, como é sabido, apenas contemplava a cultura de tipo erudito, isto é, literária, filosófica ou artística. Para isso contribuíram ciências como a antropologia, a etnologia e a sociologia, mas também as novas concepções do homem e da vida, estudadas e veiculadas pela história. Assim, falamos hoje de cultura de povos primitivos, de cultura operária, de cultura industrial ou de cultura material. Em alguns casos, o adjectivo cultural é mesmo utilizado para caracterizar toda uma civilização, como sucede com o recente livro publicado em França, da autoria de Fumarioli, intitulado precisamente L'État culturel. Essai sur une religion modern. Neste contexto, caracterizado por uma certa revalorização e vulgarização do cultural - e, simultaneamente, pelo reforço do papel desempenhado pela empresa -, não surpreende que o interesse pela temática cultura de empresa tenha vindo a aumentar, de forma notória. Já se afirmou não existir hoje discurso sobre a empresa que não fale de cultura. Daí o assunto ter entrado na ordem do dia de publicações, especializadas ou mesmo de carácter mais genérico - como periódicos ou semanários -, conferências, seminários, ensino e investigação. Parece-me, assim, estar suficientemente justificada a inclusão do tema nestas Jornadas, visto tratar-se, como veremos oportunamente, de um instrumento fundamental para uma gestão moderna e actualizada.
description: Gestão e Desenvolvimento, n. 1 (1992)
A adesão de Portugal às Comunidades Europeias e as relações comerciais com os países terceiros
Creators: name: Cunha, Luís Pedro
Publisher: name: Gestão e Desenvolvimento
Year: 1992

description: Podemos encarar a política comercial portuguesa de 1948 a 1986 como tendo sido, institucionalmente, a face visível de um longo processo de internacionalização da nossa economia (neste sentido, SILVA, 1989: 87). Mesmo que tal processo de internacionalização se tenha, por fim, revelado funcionalmente como processo de transição para a entrada nas Comunidades Europeias (CEE) (MACEDO e outros, 1988: 29).
description: Gestão e Desenvolvimento, n. 1 (1992)
As preferências dos jovens para o ingresso no ensino superior
Creators: name: Lacerda, Armando
name: Ferreira, Graça
Publisher: name: Gestão e Desenvolvimento
Year: 1992

description: Desde 1967, data em que S. Ex.ª Rev.ª o Cardeal Cerejeira benze solenemente e coloca a primeira pedra da actual sede da Universidade Católica Portuguesa, que o crescimento em qualidade académica, em instalações que viabilizam os seus projectos e em novos Centros no território nacional se apresenta como um grande desafio. A expansão da Universidade Católica no território nacional passa pela elaboração de um plano de médio a longo prazo, estando presentemente a iniciar a sua actividade em Leiria e na Figueira da Foz. Passa, igualmente, pelo desenvolvimento dos Centros já em funcionamento, com novos cursos em Lisboa, Porto, Braga e Viseu.
description: Gestão e Desenvolvimento, n. 1 (1992)
title: Συμμόρφωση υπάρχοντος πλοίου με τις απαιτήσεις του Πολικού Κώδικα του Διεθνούς Ναυτιλιακού Οργανισμού
title: Compliance of an existing ship with the requirements of the International Maritime Organization's Polar Code
titleType: AlternativeTitle
Creators: name: Πατρίκιος, Γρηγόριος
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Πολικός Κώδικας
Διεθνής Ναυτιλιακός Οργανισμός
Κατασκευαστική αντοχή
IMO
IACS
UR I1 & I2
Δεξαμενόπλοιο

description: Η παρούσα διπλωματική εργασία πραγματεύεται την ανασκόπηση των απαιτήσεων του Πολικού Κώδικα του Διεθνούς Ναυτιλιακού Οργανισμού (International Maritime Organization) καθώς και την ανασκόπηση των περιγραφικών απαιτήσεων (Unified Requirements) της Διεθνούς Ένωσης Νηογνωμόνων (International Association of Classification Societies - IACS). Πιο συγκεκριμένα θα αναφερθούν οι περιγραφικές απαιτήσεις που περιγράφονται στα UR I1 & I2. Οι παραπάνω κανονισμοί περιγράφουν απαιτήσεις που αφορούν πολλά στοιχεία του πλοίου, όπως η ευστάθεια, οι εγκαταστάσεις τηλεπικοινωνιών, συστήματα διάσωσης, η διαμερισματοποίηση καθώς και η πρόληψη της θαλάσσιας ρύπανσης από τα πλοία. Σε αυτούς του κανονισμούς αναφέρεται ο Πολικός Κώδικας του IMO. Οι περιγραφικές απαιτήσεις του IACS προβάλλουν απαιτήσεις που αφορούν την κατασκευαστική αντοχή του πλοίου. Πιο συγκεκριμένα αναφέρονται στα scantlings, ουσιαστικά, των ενισχυτικών και των ελασμάτων καθώς και στις απαιτήσεις της κύριας μηχανολογικής εγκατάστασης. Στην παρούσα εργασία θα γίνει ο έλεγχος των τελευταίων για ένα υπάρχον δεξαμενόπλοιο.
Additional file 1 of Systematic analyses of the role of prognostic and immunological EIF3A, a reader protein, in clear cell renal cell carcinoma
Creators: name: Zhang, Yi
name: Hua, Xiaoliang
name: Shi, Haoqiang
name: Zhang, Li
name: Xiao, Haibing
name: Liang, Chaozhao
Publisher: name: figshare
Year: 2021
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Table S1. Gene sets enrichment analysis of high EIF3A mRNA expression level in the ccRCC based on KEGG database. Table S2. Gene sets enrichment analysis of high EIF3A mRNA expression level in the ccRCC based on GO database. Table S3. The correlation of analysis between EIF3A and relate genes markers of immune cells in TIMER datase. Figure S1. The expression level of EIF3A in colon para-cancerous tissues and pancreatic para-cancerous tissues; Immunohistochemical (IHC) analysis of EIF3A expression in colon para-cancerous tissues (a) and pancreatic para-cancerous tissues(b). Figure S2. Eif3A was expressed in Myeloid-derived suppressor cells and Regulatory T cells by immunofluorescence assay; a Myeloid-derived suppressor cells (MDSC) cells (white arrow) were double immunostained with anti-CD11b antibody (red) and anti-EIF3A antibody (green). The cell nuclei were counterstained with DAPI (blue). The co-localization between the two endogenous proteins CD11b and EIF3A is shown in the merge panel. Scale bar, 20 mm; b Regulatory T cells (white arrow) were double immunostained with anti-Foxp3 antibody (red) and anti-EIF3A antibody (green). The cell nuclei were counterstained with DAPI (blue). The co-localization between the two endogenous proteins Foxp3 and EIF3A is shown in the merge panel. Scale bar, 20 mm.
Vicarious Liability in Groups of Companies and in Supply Chains - Is Competition Law Leading the Way?
Creators: name: Ulfbeck, Vibe
Publisher: name: Market and Competition Law Review
Year: 2019

description: The article discusses the concept of vicarious liability in the area of competition law. It argues that this concept is to some extent embedded in the concept of the undertaking under competition law with the consequence that parent companies – under certain conditions – can be held liable for competition law infringements committed by subsidiaries. The liability can be termed “vicarious” because it is imposed regardless of whether the parent company was involved in or ought to have had any knowledge of the competition law infringements committed by the subsidiary. Whereas such liability has until recently only been imposed for administrative fines, the Skanska decision changes this. Following this decision it must be assumed that parent companies can also be held vicariously liable for civil liability incurred by a subsidiary. It is pointed out that it is a separate question whether the Akzo-presumption rule, established with regard to the imposition of fines for competition law infringements, can also be applied in a pure civil liability case concerning parental liability. Next, the article discusses whether the results reached in the area of competition law can be transferred to other areas of the law. In this regard, the article analyses recent case law with regard to parental liability for workers’ injuries and environmental damage and compares these areas of the law to competition law. Finally, the article discusses whether the concept of the undertaking can be extended to apply also in situations where companies are not tied by ownership but by contract. In this regard the article focuses on the (possibly) emerging concept of supply chain liability.
description: Market and Competition Law Review, v. 3 n. 2 (2019)
title: 01_1281
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: Laboratoire de Médiévistique Occidentale de Paris
subject: LaMOP

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
title: Aνασκόπηση τελευταίων εξελίξεων και τάσεων στην διοίκηση μάνατζμεντ νοσοκομείων και εφαρμογές στην Ελλάδα
title: Review of the latest developments and trends in hospital management and applications in Greece
titleType: AlternativeTitle
Creators: name: ΖΟΥΜΑΚΗ, ΕΥΑΓΓΕΛΙΑ
Publisher: name: Πανεπιστήμιο Δυτικής Αττικής
Year: 2024
Subjects: Υγειονομικό Σύστημα
Οργανισμοί Υγείας
Διοίκηση νοσοκομείων
Management
Hospital management
Healthcare organizations
Healthcare system

description: Σκοπός: Η παρούσα διπλωματική εργασία εμβαθύνει στο management και στη διοίκηση της υγειονομικής περίθαλψης, με ιδιαίτερη έμφαση στο ελληνικό σύστημα υγειονομικής περίθαλψης, και συγκεκριμένα στο νοσοκομείο «Υγεία», διεξάγοντας μια συγκριτική ανάλυση με τις δυτικοευρωπαϊκές πρακτικές. Με φόντο το εξελισσόμενο τοπίο της υγειονομικής περίθαλψης, που χαρακτηρίζεται από τεχνολογικές εξελίξεις, ρυθμιστικές αλλαγές και μεταβαλλόμενες προσδοκίες των ασθενών, η παρούσα έρευνα αποσκοπεί στην ανάλυση των επιμέρους διακρίσεων μεταξύ της διοίκησης και του management στο πλαίσιο της υγειονομικής περίθαλψης. Η μελέτη χρησιμοποιεί βιβλιογραφική ανασκόπηση, η οποία συμπληρώνεται από μελέτη περίπτωσης, για να διερευνήσει τη δυναμική της διαχείρισης της υγειονομικής περίθαλψης και τις στρατηγικές απαντήσεις στις σύγχρονες προκλήσεις. Υλικό - Μέθοδος: Μια καίρια μελέτη περίπτωσης του νοσοκομείου «Υγεία» στην Ελλάδα χρησιμεύει ως ακρογωνιαίος λίθος αυτής της ανάλυσης, αναδεικνύοντας την ανθεκτικότητα και τη στρατηγική οξυδέρκεια της διοίκησής του για την επίτευξη οικονομικής σταθερότητας και λειτουργικής αποτελεσματικότητας. Αυτό αντιπαραβάλλεται με τη διερεύνηση των αποκεντρωμένων μοντέλων διακυβέρνησης νοσοκομείων στη Δυτική Ευρώπη, αποκαλύπτοντας πιθανά οφέλη όπως η αυξημένη αυτονομία, η βελτιωμένη ανταπόκριση στις τοπικές ανάγκες υγειονομικής περίθαλψης και η ενισχυμένη ικανότητα για καινοτομία. Η αποτελεσματική διοίκηση αναδεικνύεται ως μια δυναμική διαδικασία που ενσωματώνει τον στρατηγικό σχεδιασμό, αγκαλιάζει την καινοτομία και διατηρεί τον ασθενοκεντρικό προσανατολισμό, εξασφαλίζοντας τη βιωσιμότητα και την ποιότητα της παροχής υγειονομικής περίθαλψης. Αποτελέσματα: Η παρούσα εργασία συμβάλλει στη βιβλιογραφία για τη διοίκηση και το management της υγειονομικής περίθαλψης, προσφέροντας πρακτικές ιδέες για τους υπεύθυνους χάραξης πολιτικής, τους διοικητικούς υπαλλήλους της υγειονομικής περίθαλψης και τους διευθυντές. Υποστηρίζει μια ισορροπημένη και προσαρμοστική προσέγγιση στη διακυβέρνηση της υγειονομικής περίθαλψης, τονίζοντας την ανάγκη στρατηγικής πρόβλεψης και καινοτόμων λύσεων για την πλοήγηση στις πολυπλοκότητες του τομέα της υγειονομικής περίθαλψης. ii ΛΕΞΕΙΣ ΚΛΕΙΔΙΑ: Διοίκηση, Management, Οργανισμοί Υγείας, Management στην υγειονομική περίθαλψη, Νοσοκομείο «Υγεία», Υγειονομικό Σύστημα
REDUCING POSTOPERATIVE REINTUBATIONS THROUGH A RISK ASSESSMENT AID
Creators: name: Jacqueline Otake
name: Caroline Tan
name: Grace Troyer
Publisher: name: Zenodo
Year: 2023
Subjects: postoperative reintubation
unexpected intubation
postoperative respiratory failure
risk assessment aid
infographic

description: Postoperative reintubation (POR) is a major anesthetic adverse event that is defined by the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP, 2015) as the unplanned placement of an endotracheal tube or similar airway device within 30 days after surgery with general anesthesia. POR is a serious complication associated with an increase in hospital length of stay, patient morbidity, and mortality. Furthermore, POR is associated with cardiac, pulmonary and renal complications which all often result in increased hospital costs. Objective: Develop a risk assessment aid with standardized treatment recommendations based on risk level in order to increase POR awareness and education among anesthesia providers. Design: An extensive review of the literature was performed to identify factors associated with POR. Factors were also derived from secondary data analysis from previous DNP project findings. POR factors were then evaluated with the use of a Delphi Study which was deployed to expert participants in the field. Setting: Kaiser Permanente School of Anesthesia, Pasadena, California. Results: Three rounds of the Delphi Study were performed, and eleven risk factors were highly associated with POR. A consensus was reached among participants on whether these risk factors put the patient at mild, moderate, or high risk for POR. Conclusions: A risk assessment aid and provider recommendations were organized into an infographic. Plans for future implementation were outlined.
title: Ultimate limits of reinforced concrete hinges
Creators: name: Schlappal, Thomas
name: Kalliauer, Johannes
name: Vill, Markus
name: Mang, Herbert
name: Eberhardsteiner, Josef
name: Pichler, Bernhard
Publisher: name: ELSEVIER SCI LTD
Year: 2020
Subjects: ultimate limit states (ULS)
Integral bridges
Design Recommendations

description: This work is a further development of its predecessor, the topic of which was verification of serviceability limit states of reinforced concrete hinges. Herein, the same conceptual approach is used to derive analytical formulae, supporting verification of ultimate limit states. These formulae limit tolerable relative rotations as a function of the compressie normal force transmitted across the neck. The mechanical model is based on the Bernoulli-Euler hypothesis and on linear-elastic and ideally-plastic stress-strain relationships for both concrete in compression and steel in tension. The usefulness of the derived formulae and the corresponding dimensionless design dia-grams is assessed by means of experimental data from structural testing of reinforced concrete hinges, taken from the literature. This way, it is shown that the proposed mechanical model is suitable for describing ultimate limit states. Corresponding design recommendations are elaborated and exemplarily applied to verification of ultimate limit states of the reinforced concrete hinges of a recently built integral bridge. Since the reinforcement is explicitly accounted for, the tolerable relative rotations are larger than those according to existing guidelines. It is included that bending-induced tensile macrocracking beyond one half of the smallest cross-section of the neck is acceptable, because the tensile forces carried by the reinforcement ensure the required position stability of the hinges.
title: Ψηφιακή ανάδειξη του αρχαιολογικού χώρου Πετρών με το «ArcGIS StoryMaps» και η χρήση καινοτόμων ελεύθερων εργαλείων στην προβολή αρχαιολογικού υλικού
title: The digital projection of the archaeological site of Petres with "ArcGIS StoryMaps" and the use of innovative tools in the promotion of archaeological information
titleType: AlternativeTitle
Creators: name: Τρυφωνίδου, Άννα
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2024
Subjects: subject: Ψηφιακός πολιτισμός
subject: Ψηφιακή αρχαιολογία
subject: Ψηφιακά μέσα
subject: Εμπειρία χρήστη
subject: Digital culture
subject: Digital archaeology
subject: Digital tools
subject: User’s experience

description: Η παρούσα Μεταπτυχιακή Διατριβή (ΜΔ) έχει ως βασικό στόχο, τη κατάδειξη των ελεύθερων ψηφιακών εργαλείων στη ψηφιοποίηση της Αρχαιολογίας. Στο εγχείρημα αυτό χρησιμοποιήσαμε ως παράδειγμα ψηφιοποίησης Αρχαιολογικού υλικού, τον Αρχαιολογικό χώρο Πετρών, μια θέση υψίστης σημασίας για τη Δυτική Μακεδονία. Τα εργαλεία που χρησιμοποιήθηκαν στα πλαίσια της μελέτης αυτής ήταν το «ArcGIS StoryMaps», το «Artsteps» και το «Adalo». Eργαλεία που επιλέχθηκαν για τη δημιουργία των πιλοτικών κατασκευών και τη ψηφιακή προβολή της Ελληνιστικής πόλης Πετρών. Δόθηκε έμφαση στον συνδυασμό της Αρχαιολογίας με τη Γεωγραφία, ενώ ταυτόχρονα εξετάστηκαν οι καινοτόμες δυνατότητες που προκύπτουν με την ενεργή «συμμετοχή» της Τεχνολογίας στον τομέα του Πολιτισμού. Οι κατασκευές συμπεριλαμβάνουν, μια ιστορική-χαρτογραφική παρουσίαση, η οποία υπογραμμίζει τη χρήση του νέου όρου της «Γεωαρχαιολογίας», μια ψηφιακή περιήγηση με πλούσιο υλικό από τον Αρχαιολογικό χώρο και μια αρχαιολογικού περιεχομένου εφαρμογή (App) για την ανάδειξη της θέσης. Τα δημιουργήματα αυτά αξιολογήθηκαν και το θετικό αποτέλεσμα που είχαμε, μας επιβεβαίωσε πως η χρήση της σύγχρονης τεχνολογίας στη ανάδειξη και προβολή Πολιτιστικού περιεχομένου και της Αρχαιολογίας είναι κάτι που επιφέρει θετικά και κυρίως εξελίξιμα αποτελέσματα. Μετά την ανάλυση και την απόδοση λεπτομερειών των κατασκευών και των εργαλείων που χρησιμοποιήθηκαν, αποφασίσαμε να ολοκληρώσουμε την εργασία αυτή με τη χρήση του «NVivo», ενός άλλου ψηφιακού μέσου για την ποιοτική ανάλυση των δεδομένων της έρευνας που διεξήχθη. Το εργαλείο αυτό έπαιξε σημαντικό ρόλο στην ολοκλήρωση της ποιοτικής ανάλυσης του υλικού της ΜΔ καθώς με αυτόν τον τρόπο δόθηκε έμφαση, πέρα από τη ψηφιακότητα στον τομέα του Πολιτισμού, και στους θεωρητικούς άξονες που ακολουθήθηκαν και μας οδήγησαν στα αποτελέσματα που είχαμε.