cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: DEPRECATED: Systems approach to documentary maritime fraud
Creators: name: Kapoor, Peter
Publisher: name: University of Plymouth
Year: 1987
Subjects: subject: International trade fraud
subject: Economics
subject: Ships
subject: Offshore structures
subject: Law
subject: FOS: Law

description: Wring the last decade documentary maritime fraud has caused considerable financial loss. The internationality of the crime and the difficulties experienced in the investigation and prosecution of offenders has caused serious concern both nationally and internationally. The aim of this research was to examine the system of international trade in terms of flow between institutions, and to develop a model of the system to identify areas of system failures in terms of actual or potential frauds. A database consisting of 101 fraud cases was compiled. Detailed examination of the cases identified features common to different classes of fraud. Systems approach was used to investigate the system with particular reference to Bills of Lading and method of payment under documentary credits. Conceptual mcdels of the three main contractual sub-systems i. e. carriage, insurance and payment, and of the total system were developed. The latter was used in conjunction with the database to pin-point the weak links both within the system and its imiediate envirormLent. Using a rwlti-disciplinary international Panel of Experts the Delphi technique, appropriately modified, was employed to test the hypothesised weak links, determine feasibility of implementing the recoamndations and seek information to assist in introducing measures to combat fraud. The analysis supports the hypothesised weak links identified in the environment and reccmuendations to strengthen them. Factors creating an environment for fraud are identified, along with reasons for not reporting the crime. Information required to combat fraud is identified. Prior to payment under documentary credits banks should carry out factual checks. The Bill of Lading is not a weak link but the people handling the document are unaware of its importance. Establishmnt of a Conmrcial Crim Research Unit specialising in international trade is recamrended, as is the development of an educational prograrmTo to increase conmercial awareness.
Estimating inundation extent and depth from national water model outputs and high resolution topographic data
Creators: name: Schomp, Robert Anthony
Publisher: name: The University of Texas at Austin
Year: 2021
Subjects: Flood inundation mapping
GeoNet
GeoFlood
Height above nearest drainage
High-resolution terrain data
Raster comparison

description: Recent flood disasters, such as Hurricane Harvey in 2017, have emphasized the need for computationally quick simulations of flood inundation over large spatial scales. The purpose of this study is to address the National Oceanic and Atmospheric Administration's priority goal by enhancing inundation mapping with the GeoFlood workflow. The GeoFlood flood inundation mapping approach integrates the GeoNet and Height Above Nearest Drainage methods. GeoNet utilizes high-resolution topographic data and geodesic minimization principles to extract channel networks. Then, the Height Above Nearest Drainage method is used to determine synthetic rating curves and channel hydraulic properties. Finally, the National Water Model discharge forecasts are correlated with stage heights to produce real-time flood inundation extent and depth maps. For this study, GeoFlood's computational advantages were leveraged at the Texas Advanced Computing Center to produce Hurricane Harvey flood inundation maps across seven Texas counties on a Hydrologic Unit Code 12 watershed scale. Improvement was quantified by comparing a traditional medium-resolution Height Above Nearest Drainage approach versus the GeoFlood workflow. The most significant channel and terrain characteristics used to quantify improvements were topographic relief, slope, and stream order. Performance was measured by comparing the 10-meter resolution Height Above Nearest Drainage and 1-meter resolution GeoFlood inundation maps versus the Federal Emergency Management Agency Hurricane Harvey flood depths grid and United States Geological Service Hurricane Harvey High Water Mark benchmarks. GeoFlood performance enhancements were greatest in low relief, low slope, and densely developed regions as well as across a majority of Strahler stream orders. GeoFlood increased inundation mapping performance in both extent and depth. Limitations of the approach included segment catchment filling as well as the lack of pluvial and coastal flood hazard components. Overall, this study supports the integration of high-resolution terrain data into flood inundation mapping via the GeoFlood workflow.
Towards exact field theory results for the Standard Model on fractional D6-branes
Creators: name: Honecker, Gabriele
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Fractional D6-branes on toroidal orbifold backgrounds are known to be able to accommodate the particle spectrum and gauge group of the Standard Model, but up to now exact results for their low-energy effective action are missing. Here we discuss how the conceptual ansatz of matching the string theoretic gauge couplings at one-loop with the supergravity expressions is generalised from the six-torus to orbifold backgrounds on which the Standard Model spectrum can be realised on fractional D6-branes. The Kaehler metrics and perturbatively exact holomorphic gauge kinetic functions can be classified in terms of the vanishing of some intersection angle and the related beta function coefficients, which potentially opens the possibility to extrapolate to smooth Calabi-Yau backgrounds.
description: 1+3 pages, 2 tables; proceedings of the EPS-HEP 2011 conference in Grenoble 21-27 July 2011; v2: introduction and conclusion extended, published version
Barbero-Immirzi parameter, manifold invariants and Euclidean path integrals
Creators: name: Liko, Tomas
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The Barbero-Immirzi parameter $γ$ appears in the \emph{real} connection formulation of gravity in terms of the Ashtekar variables, and gives rise to a one-parameter quantization ambiguity in Loop Quantum Gravity. In this paper we investigate the conditions under which $γ$ will have physical effects in Euclidean Quantum Gravity. This is done by constructing a well-defined Euclidean path integral for the Holst action with non-zero cosmological constant on a manifold with boundary. We find that two general conditions must be satisfied by the spacetime manifold in order for the Holst action and its surface integral to be non-zero: (i) the metric has to be non-diagonalizable; (ii) the Pontryagin number of the manifold has to be non-zero. The latter is a strong topological condition, and rules out many of the known solutions to the Einstein field equations. This result leads us to evaluate the on-shell first-order Holst action and corresponding Euclidean partition function on the Taub-NUT-ADS solution. We find that $γ$ shows up as a finite rotation of the on-shell partition function which corresponds to shifts in the energy and entropy of the NUT charge. In an appendix we also evaluate the Holst action on the Taub-NUT and Taub-bolt solutions in flat spacetime and find that in that case as well $γ$ shows up in the energy and entropy of the NUT and bolt charges. We also present an example whereby the Euler characteristic of the manifold has a non-trivial effect on black-hole mergers.
description: 18 pages; v2: references added; to appear in Classical and Quantum Gravity; v3: typos corrected; minor revisions to match published version
Critical behavior of Born Infeld AdS black holes in higher dimensions
Creators: name: Banerjee, Rabin
name: Roychowdhury, Dibakar
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Based on a canonical framework, we investigate the critical behavior of Born-Infeld AdS black holes in higher dimensions. As a special case, considering the appropriate limit, we also analyze the critical phenomena for Reissner Nordstrom AdS black holes. The critical points are marked by the divergences in the heat capacity at constant charge. The static critical exponents associated with various thermodynamic entities are computed and shown to satisfy the thermodynamic scaling laws. These scaling laws have also been found to be compatible with the static scaling hypothesis. Furthermore, we show that the values of these exponents are universal and do not depend on the spatial dimensionality of the AdS space. We also provide a suggestive way to calculate the critical exponents associated with the spatial correlation which satisfy the scaling laws of second kind.
description: LaTex, 22 pages, 12 figures, minor modifications in text, To appear in Phys. Rev. D
Examining the Association between Late-Life Depressive Symptoms, Cognitive Function, and Brain Volumes in the Context of Cognitive Reserve
Creators: name: O'Shea, Deirdre M.
name: Fieo, Robert A.
name: Hamilton, Jamie L.
name: Zahodne, Laura B.
name: Manly, Jennifer J.
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 2015
Subjects: Neurology
Depression, Mental
Geriatric psychiatry
Cognition

description: Objective: The present study aimed to investigate whether cognitive reserve moderated the association between depressive symptoms and cognition, as well as brain volumes in a sample of older adults. Methods: Non-demented participants (n = 3484) were selected from the Washington Heights/Hamilton Heights Inwood Columbia Aging Project (Northern Manhattan). A subsample of these participants without dementia (n = 703), who had brain imaging data, was also selected for a separate analysis. Depressive symptomatology was assessed with the 10-item Center for Epidemiologic Studies Depression Scale. Reading level and years of education were used as measures of cognitive reserve. Four distinct cognitive composite scores were calculated: executive function, memory, visual-spatial, and language. Results: Multiple regression analysis revealed interaction effects between both measures of cognitive reserve and depressive symptoms on all the cognitive outcome measures except for visual-spatial ability. Those with greater reserve showed greater cognitive decrements than those with lower levels of reserve as depressive symptoms increased. A borderline interaction effect was revealed between reading level and depressive symptoms on total brain volumes. Those with lower reading scores showed greater volume loss as depressive symptoms increased than those with higher reading scores. Conclusions: Our findings indicate that the association between late-life depressive symptoms and core aspects of cognition varies depending on one's level of cognitive reserve. Those that had greater levels of education and/or reading ability showed a greater decrease in memory, executive, and language performances as depressive symptoms increased than those with lower years of education and reading ability. Copyright (C) 2014 John Wiley & Sons, Ltd.
New cooling curve due to the updates of collisional excitation in the plasma code SPEX
Creators: name: Štofanová, Lýdia
Publisher: name: Zenodo
Year: 2019
Subjects: plasma
astronomy
astrophysics
X-ray
plasma code
atomic data
atomic database
collisional excitation
collisional ionisation equilibrium
photo-ionisation equilibrium

description: The contribution talk at XCalibur 2019 workshop in Winchester. For more details see the accepted version of the publication Štofanová et al. (2021) in Astronomy & Astrophysics journal.
description: {"references": ["\u0160tofanov\u00e1, L. (2019)", "Stofanov\u00e1, L. (2019)", "Stofanova, L. (2019)"]}
Relevance Feedback for Goal's Extraction from Fuzzy Semantic Networks
Creators: name: Omri, Mohamed Nazih
Publisher: name: arXiv
Year: 2012
Subjects: subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: In this paper we present a short survey of fuzzy and Semantic approaches to Knowledge Extraction. The goal of such approaches is to define flexible Knowledge Extraction Systems able to deal with the inherent vagueness and uncertainty of the Extraction process. It has long been recognised that interactivity improves the effectiveness of Knowledge Extraction systems. Novice user's queries is the most natural and interactive medium of communication and recent progress in recognition is making it possible to build systems that interact with the user. However, given the typical novice user's queries submitted to Knowledge Extraction systems, it is easy to imagine that the effects of goal recognition errors in novice user's queries must be severely destructive on the system's effectiveness. The experimental work reported in this paper shows that the use of classical Knowledge Extraction techniques for novice user's query processing is robust to considerably high levels of goal recognition errors. Moreover, both standard relevance feedback and pseudo relevance feedback can be effectively employed to improve the effectiveness of novice user's query processing.
description: arXiv admin note: substantial text overlap with arXiv:1206.0925, arXiv:1206.1615
Complex Scalar Singlet Dark Matter: Vacuum Stability and Phenomenology
Creators: name: Gonderinger, Matthew
name: Lim, Hyungjun
name: Ramsey-Musolf, Michael J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We analyze one-loop vacuum stability, perturbativity, and phenomenological constraints on a complex singlet extension of the Standard Model (SM) scalar sector containing a scalar dark matter candidate. We study vacuum stability considerations using a gauge-invariant approach and compare with the conventional gauge-dependent procedure. We show that, if new physics exists at the TeV scale, the vacuum stability analysis and experimental constraints from the dark matter sector, electroweak precision data, and LEP allow both a Higgs-like scalar in the mass range allowed by the latest results from CMS and ATLAS and a lighter singlet-like scalar with weak couplings to SM particles. If instead no new physics appears until higher energy scales, there may be significant tension between the vacuum stability analysis and phenomenological constraints (in particular electroweak precision data) to the extent that the complex singlet extension with light Higgs and singlet masses would be ruled out. We comment on the possible implications of a scalar with ~125 GeV mass and future ATLAS invisible decay searches.
description: 24 pages, 12 figures; v2 - fixed minor typos, added reference, changed layout
Additional file 1 of Association of PTX3 gene polymorphisms and PTX3 plasma levels with leprosy susceptibility
Creators: name: Moraes, Ana Clara Cadidé Gonzaga
name: da Luz, Renata Clesia Feitosa Viana
name: Fernandes, André Luís Magalhães
name: Barbosa, Milena Xavier Silva
name: de Andrade, Lorena Viana
name: Armstrong, Anderson da Costa
name: de Souza, Carlos Dornels Freire
name: do Carmo, Rodrigo Feliciano
Publisher: name: figshare
Year: 2023
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: Supplementary Material 1: Figure S1. Association of PTX3 plasma levels (ng/mL) and PTX3 polymorphisms (A) rs1840680 and (B) rs2305619. Statistical significance was determined using the Kruskal-Wallis test. ns: non-significant
Non-Abelian Localization for Supersymmetric Yang-Mills-Chern-Simons Theories on Seifert Manifold
Creators: name: Ohta, Kazutoshi
name: Yoshida, Yutaka
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive non-Abelian localization formulae for supersymmetric Yang-Mills-Chern-Simons theory with matters on a Seifert manifold M, which is the three-dimensional space of a circle bundle over a two-dimensional Riemann surface Σ, by using the cohomological approach introduced by Kallen. We find that the partition function and the vev of the supersymmetric Wilson loop reduces to a finite dimensional integral and summation over classical flux configurations labeled by discrete integers. We also find the partition function reduces further to just a discrete sum over integers in some cases, and evaluate the supersymmetric index (Witten index) exactly on S^1xΣ. The index completely agrees with the previous prediction from field theory and branes. We discuss a vacuum structure of the ABJM theory deduced from the localization.
description: 50 pages, 3 figures, typos corrected, references added
Clinical Correlates of Alzheimer's Disease with and without Silent Radiographic Abnormalities
Creators: name: Marder, Karen
name: Richards, Marcus
name: Bello, Jacqueline
name: Bell, Karen L.
name: Sano, Mary
name: Miller, Lisa
name: Folstein, Marshal
name: Albert, Marilyn
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 1995
Subjects: Neurology
Radiography, Medical
Alzheimer's disease--Patients

description: Objective: To determine whether patients with Alzheimer's disease (AD) who do not have historical or clinical evidence of stroke but who do have computed tomographic or magnetic resonance imaging evidence of noncortical lesions smaller than 2 cm or periventricular "caps" differ from other patients with AD. Methods: The computed tomographic or magnetic resonance imaging scans of 158 patients meeting criteria of the National Institute of Neurological Disorders and Stroke—Alzheimer's Disease and Related Disorders Association for probable AD were reviewed by one neuroradiologist. Two measures of disease severity—the Modified Mini-Mental State examination and the Blessed Dementia Rating Scale (Part I)—were subjected to two-way analysis of variance with scan type (computed tomography or magnetic resonance imaging) and lesion number as between-group factors and age and disease duration as covariates. Results: No relationship was seen between lesion number or periventricular caps and disease severity. Conclusion: In this cross-sectional analysis using these clinical measures, patients with AD who have well-defined radiographic abnormalities cannot be differentiated from patients with AD who do not have them.
On High Moments and the Spectral Norm of Large Dilute Wigner Random Matrices
Creators: name: Khorunzhiy, Oleksiy
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences
subject: 15B52, 60F99

description: We consider a dilute version of the Wigner ensemble of n-dimensional random matrices H such that each row has in average ρ_n non-zero elements. We study asymptotic properties of the spectral norm of H on the scale n^{-2/3} in the limit when ρ_n is of the order n^{-2/3(1+ε)} with ε>0.
description: Final version to appear in "Journal of Mathematical Physics, Analysis and Geometry"
(Un)belongings : Muslim women in multicultural Canada
Creators: name: Kraft, Molly
Publisher: name: University of British Columbia
Year: 2012

description: In this thesis I explore the way Muslim women in Vancouver, B.C. narrate stories of belonging. Addressing the way in which Muslim women have become a popular symbol for the perceived incompatibility of multiculturalism and specific cultural practices, I focus on how this group has been affected — resists and negotiates — the changes to Canadian policy and the social landscape in the last two decades. I examine how these women come to see themselves in relation to the framing of their social, cultural and religious practices as inherently incompatible with aspects of Canadian society. What stories of belonging do they tell? How are these affected, produced, or outside of, state narratives of being in Canada? I draw from feminist, anti-racist scholarship calling for more nuanced and critical approaches to concepts of integration, multiculturalism and nationalism. I argue that these women’s stories can best be understood through the theoretical lens of (un)belonging; spaces, moments and attachments that develop outside of normative belonging. Finally, I seek to ask whether we can “keep our senses open to emergent and unknown forms of belonging, connectivity” and “intimacy” (Puar 2007, p. xxviii) and what these might inform or enliven in studies of immigration, settlement and multiculturalism in Canada.
Depressive Symptoms in Alzheimer's Disease: Natural Course and Temporal Relation to Function and Cognitive Status
Creators: name: Holtzer, Roee
name: Scarmeas, Nikolaos
name: Wegesin, Domonick
name: Albert, Marilyn
name: Brandt, Jason
name: Dubois, Bruno
name: Hadjigeorgiou, Georgios
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 2005
Subjects: Neurology
Alzheimer's disease--Patients
Cognition
Geriatrics
Depression, Mental

description: OBJECTIVES: To examine the natural course of depressive symptoms in patients with probable Alzheimer's disease (AD), specifically, the temporal relationship between depressive symptoms, function, and cognitive status. DESIGN: Multicenter cohort study with follow-up of up to 14 years. SETTING: Patients from the two Multicenter Study of Predictors of Disease Course in Alzheimer's Disease (Predictors Study) cohorts were recruited at five sites in the United States and Europe. PARTICIPANTS: Patients diagnosed with probable AD (n=536) enrolled in a longitudinal study (Predictors Study). MEASUREMENTS: Depressive symptoms were evaluated at 6-month intervals using the Columbia Scale for Psychopathology in Alzheimer's Disease. The Modified Mini-Mental State (3MS) and Blessed Dementia Rating Scale (BDRS) were used to assess cognitive status and functional activity, respectively. RESULTS: The prevalence of depressive symptoms was stable over the first 3 years of follow-up, at approximately 40%. There was a significant drop to 28% and 24% in the fourth and fifth years of follow-up, respectively. Time-dependent Cox analysis revealed that functional activity (BDRS) but not cognitive status (3MS) was a significant predictor of the first episode of depressive symptoms during follow-up. Generalized estimating equation analyses showed that AD duration and functional activity but not cognitive status were significantly related to depressive symptoms over the entire follow-up period. CONCLUSION: Depressive symptoms are common in AD, but their prevalence decreases over time. Examination of the temporal relationship between depressive symptoms and risk factors suggests that decline in function but not in cognition precedes the first episode of depressive symptoms in patients with probable AD.
Assessing Patient Dependence in Alzheimer's Disease
Creators: name: Stern, Yaakov
name: Albert, Steven M.
name: Sano, Mary
name: Richards, Marcus
name: Miller, Lisa
name: Folstein, Marshal
name: Albert, Marilyn
name: Bylsma, Fred W.
name: Lafleche, Ginette
Publisher: name: Columbia University
Year: 1994
Subjects: Neurology
Alzheimer's disease--Patients
Cognition
Gerontology

description: Background. While cognitive and functional deficits are the hallmark of Alzheimer's disease (AD), loss of social function (and the dependence this implies) is also critical, especially in early stages of disease. Little attention has been directed to this facet of dementing disease. We describe a scale for assessing dependency in AD and present a baseline profile of dependency in a cohort of AD patients. Methods. In a study of the predictors of the course of AD, 233 patients in early stages of disease (modified MMS ≥ 30) were assessed. Psychometric properties of the dependence scale were established. To validate the scale, dependence scores at baseline were correlated with a series of measures assessing cognition and function. The course of dependency over 18 months of follow-up was also analyzed. Results. The scale shows adequate reliability (test-retest, intraclass correlation). Dependence stage was related to other measures of disease severity. Scalogram analysis shows that the dependence scale is consistent with the course of functional loss established for dementing disease. Prospective data indicate sensitivity of the scale to disease progression. Conclusion. Dependency is a distinct, measurable component of dementing disease and should be considered an important outcome in studies of AD.
X-ray activity and rotation of the young stars in IC 348
Creators: name: Alexander, Frauke
name: Preibisch, Thomas
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The physical origin of the strong magnetic activity in T Tauri stars and its relation to stellar rotation is not yet well understood. We investigate the relation between the X-ray activity, rotation, and Rossby number for a sample of 82 young stars in the ~3 Myr old cluster IC 348. We use the data of four Chandra observations of IC 348 to derive the X-ray luminosities of the young stars. The young stars in IC 348 show no correlation between X-ray activity and rotation period. Considering the Rossby numbers, nearly all IC 348 stars are in the saturated regime of the activity-rotation relation defined by main-sequence stars. Searching for possible super-saturation effects, we find a marginal (but statistically in-significant) trend that the stars with the smallest Rossby numbers show slightly lower X-ray activity levels. We compare the dispersion of fractional X-ray luminosities of the stars in the saturated rotation regime in IC 348 to that seen in younger and older stellar populations. The scatter seen in the ~3 Myr old IC 348 is considerably smaller than for the ~1 Myr old ONC, but, at the same time, considerably larger than the dispersion seen in the ~30 Myr old cluster NGC 2547 and in main-sequence stars. The results of our X-ray analysis of IC 348 show that neither the rotation rates nor the presence/absence of circumstellar disks are of fundamental importance for determining the level of X-ray activity in TTS. Our results suggest that the scatter of X-ray activity levels shown by the fast-rotating members of young clusters decreases with the age of the stellar population. We interpret this as a signature of the changing interior structure of PMS stars and the consequent changes in the dynamo mechanisms that are responsible for the magnetic field generation.
description: accepted by A&A on 15th of December 2011 published in Astronomy & Astrophysics Februar 2012
Nonnegatively curved homogeneous metrics in low dimensions
Creators: name: Kerr, Megan M.
name: Kollross, Andreas
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C30 (Primary) 53C21, 57S15 (Secondary)

description: We consider invariant Riemannian metrics on compact homogeneous spaces $G/H$ where an intermediate subgroup $K$ between $G$ and $H$ exists. In this case, the homogeneous space $G/H$ is the total space of a Riemannian submersion. The metrics constructed by shrinking the fibers in this way can be interpreted as metrics obtained from a Cheeger deformation and are thus well known to be nonnegatively curved. On the other hand, if the fibers are homothetically enlarged, it depends on the triple of groups $(H,K,G)$ whether nonnegative curvature is maintained for small deformations. Building on the work of L. Schwachhöfer and K. Tapp \cite{ST}, we examine all $G$-invariant fibration metrics on $G/H$ for $G$ a compact simple Lie group of dimension up to 15. An analysis of the low dimensional examples provides insight into the algebraic criteria that yield continuous families of nonnegative sectional curvature.
description: 14 pages, to appear in Annals of Global Analysis and Geometry
Three novel quinolinone alkaloids from the leaves of Melicope denhamii
Creators: name: Saputri, Ratih Dewi
name: Retnowati, Rurini
name: Supratman, Unang
name: Tjahjandarie, Tjitjik Srie
name: Tanjung, Mulyadi
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Inorganic Chemistry

description: Three previously unreported quinolinone alkaloids: melicodenines J-L (1-3) and six known compounds (4-9), were isolated from the leaves of Melicope denhamii (Seem) T.G. Hartley. The structures of three quinolinone alkaloids were identified based on HRESIMS and NMR spectra. Compounds 1-9 were assayed in three cancer cells (MCF-7, HeLa, and P-388). Compounds 1 and 5 showed high cytotoxic activity against HeLa cells with IC50 values of 1.8 and 0.8 µM, respectively.
Town and Country: The Production and Distribution of Laverstock Wares
Creators: name: Mepham, Lorraine
Publisher: name: Archaeology Data Service
Year: 2023

description: Medieval Ceramics: Journal of the Medieval Ceramics Research Group, 39, 17-28
description: During the medieval period a widespread pottery industry existed across south-east Wiltshire and east Dorset. Its origins may lie as early as the mid-late Saxon period, and by the 13th century it was supplying urban and rural sites across the region, with one known production centre at Laverstock, near Salisbury, and almost certainly others. The evidence for differential consumption of the industry's products by urban and rural populations is discussed.
Apolipoprotein E and Alzheimer's Disease: Ethnic Variation in Genotypic Risks
Creators: name: Maestre, Gladys
name: Ottman, Ruth
name: Stern, Yaakov
name: Gurland, Barry J.
name: Chun, Michael
name: Tang, Mingxin
name: Shelanski, Michael L.
name: Tycko, Benjamin
name: Mayeux, Richard Paul
Publisher: name: Columbia University
Year: 1995
Subjects: Neurology
Apolipoprotein E
Alzheimer's disease
Medical genetics

description: The presence of the apolipoprotein E4 (apo €4) allele significantly increases the risk of Alzheimer's disease. Whether this is due to biological effects of the apo E4 protein or reflects linkage disequilibrium with an as yet unidentified Alzheimer's disease susceptibility gene is of critical importance. In a community study in northern Manhattan we found a fivefold increase in the risk of Alzheimer's disease among African-Americans, Hispanics, and whites homozygous for apo ~4. Overall, the risk between Alzheimer's disease and apo ~4 heterozygosity was also increased by twofold, but the association was somewhat weaker for African-Americans than for Hispanics and whites. In contrast, the apo e2/~3 genotype was associated with an eightfold increased risk of Alzheimer's disease in African-Americans but it was associated with reduced risk in whites. Variability in the strength and type of association between Alzheimer's disease and the apo E polymorphisms in the three ethnic groups could not be fully explained by age differences. The allelic frequency of apoe"4 was significantly higher in patients than control subjects in all ethnic groups at age 70 or younger, reflecting the higher proportion of apo E4 homozygotes, but this difference diminished with increasing age. The allelic frequency of apoe'2 for African-Americans and Hispanics, but not whites, was significantly higher in patients than control subjects, but only after age 70. Though these findings need confirmation, they suggest that modifier genes or environmenral factors may interact selectively with apo E4 in African-Americans to weaken the association with Alzheimer's disease or that the apo E allelic system is in linkage disequilibrium with a nearby, as yet unidentified Alzheimer's disease susceptibility locus.
Indoor positioning through integration of optical angles of arrival with an inertial measurement unit
Creators: name: Islam, Md. Shariful
Publisher: name: University of British Columbia
Year: 2012

description: A novel indoor positioning solution is proposed in this work. An inertial navigation system (INS) is integrated with optical angle of arrival (OAOA) measurements to yield a smoother, more accurate, and robust positioning solution for indoor environments. An extended Kalman filter (EKF) is used to integrate the INS and OAOA measurements. Four different algorithms are proposed for the novel indoor positioning solution by INS/OAOA integration. An error state Kalman filter is used for implementing all four algorithms. In previous work, magnetometer error estimation was not included in the EKF state vector. In this work, magnetometer error estimation is added to the EKF state vector, and this reduced the average position error by 3.7% to 7%. Quaternion algebra is used instead of Euler angles due to the possibility of mathematical singularities for certain Euler angles. Quaternion vector estimation is performed by adding the quaternion vector to the state vector of the EKF. Both loosely coupled and tightly coupled integration strategies are explored for INS/OAOA integration. The tightly coupled strategy reduces the average positioning error by 60% compared to an OAOA-only system while the loosely coupled strategy reduces the average error by 44%. However, the performance improvement of the tightly coupled system comes with an increased computational cost due to nonlinearities in the measurement model. The loosely and tightly coupled algorithms are modified by augmenting the observation vector with a prior accelerometer bias estimate and a quaternion vector estimate. This results in loosely and tightly coupled algorithms with augmented observations. The algorithms with augmented observations perform significantly better, especially in a case of the low update rate for the OAOA sensor. An average position error of 4.89 cm is reduced to 3.11 cm by using the loosely coupled algorithm with augmented observations instead of the loosely coupled algorithm without observation augmentation. This is an improvement of approximately 36%. For the tightly coupled system, this improvement is approximately 32%. However, where the update rate from the OAOA sensor is fast enough, no significant performance improvement is observed by using algorithms with augmented observations.
Mptp-Induced Parkinsonism. [Review]
Creators: name: Stern, Yaakov
Publisher: name: Columbia University
Year: 1990
Subjects: Neurobiology
Parkinson's disease
Methylphenyltetrahydropyridine
Neurology

description: In 1979, the publication of a little noticed article presaged a major advance in the knowledge of and research approaches to Parkinson's disease (PD) (Davis et al., 1979). The paper reported the case history of a 23-year-old man who, in 1973, developed parkinsonian symptoms including bradykinesia, rigidity and tremor which progressed to mutism and virtual paralysis over a period of days. His physicians determined that he had been preparing and self-injecting a potent meperedine analogue 1-methyl-4- phenyl-propionoxypiperidine (MPPP), apparently as a substitute for demerol. He had taken some short cuts in the preparation of the compound, resulting in the presence of a by-product, 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine (MPTP), which was apparently responsible for the parkinsonian syndrome. The patient responded to the standard dopamine replacement therapy used in PD. Following his untimely death, post-mortem examination revealed depletion of cells in the pars compacta of the substantia nigra, the characteristic pathologic change of PD. These observations suggested for the first time that exposure to a toxin might produce a disease that has no known cause.
Sizeable θ_13 from the Charged Lepton Sector in SU(5), (Tri-)Bimaximal Neutrino Mixing and Dirac CP Violation
Creators: name: Marzocca, David
name: Petcov, Serguey T.
name: Romanino, Andrea
name: Spinrath, Martin
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The recent results from T2K and MINOS experiments point towards a relatively large value of the reactor angle θ_13 in the lepton sector. In this paper we show how a large θ_13 can arise from the charged lepton sector alone in the context of an SU(5) GUT. In such a scenario (tri-)bimaximal mixing in the neutrino sector is still a viable possibility. We also analyse the general implications of the considered scenario for the searches of CP violation in neutrino oscillations.
description: 19 pages, 3 figures; version to be published in JHEP
Additional file 1 of Increased prevalence of thyroid dysfunction in Tehran – HAMRAH study
Creators: name: Ghaemmaghami, Zahra
name: Firoozbakhsh, Parisa
name: Gholami, Delara
name: Khodabandelu, Sajad
name: Baay, Mohammadreza
name: Alemzadeh-Ansari, Mohammad Javad
name: Mohebbi, Bahram
name: Hosseini, Zahra
name: Boudagh, Shabnam
name: Pouraliakbar, Hamidreza
name: Pasebani, Yeganeh
name: Rafati, Ali
name: Khalilpour, Ehsan
name: Khalili, Yasaman
name: Arabian, Maedeh
name: Maleki, Majid
name: Bakhshandeh, Hooman
name: Sadeghipour, Parham
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Characterising Post-Medieval Pottery Production Centres in Somerset
Creators: name: Dawson, David P
name: Anderson, Jens
name: Rollinson, Gavyn
Publisher: name: Archaeology Data Service
Year: 2023

description: Medieval Ceramics: Journal of the Medieval Ceramics Research Group, 39, 29-42
description: Post-medieval pottery made in Somerset is distinct from wares produced elsewhere in the south-west of England. Recent experimental work and scientific analysis, combined with study of finds from fieldwork, has led to a more complete understanding of the nature of pottery production in Somerset, how it is possible to use mineralogical and stylistic evidence to distinguish between the three major areas of earthenware production and how production changes over time.
A Ceramic View of Post-Medieval Markets and Mariners in South Wales and the Bristol Channel
Creators: name: Forward, Alice
Publisher: name: Archaeology Data Service
Year: 2023

description: Medieval Ceramics: Journal of the Medieval Ceramics Research Group, 39, 43-60
description: This paper (delivered at the MPRG 2016 conference in Taunton) examines pottery supply and consumption in post-medieval south Wales. It focusses specifically on south Glamorgan and the site of Cosmeston, which provides an important stratified assemblage and can be used as a type site from which to demonstrate ceramic use and traditions in the early post-medieval period in south Wales. After reviewing the history of post-medieval pottery studies in the region the paper discusses post-medieval pottery from two deposits at Cosmeston within the broader context of the economic and social networks of the Bristol Channel.
Motor Signs During the Course of Alzheimer Disease
Creators: name: Scarmeas, Nikolaos
name: Hadjigeorgiou, Georgios
name: Papadimitriou, Alexandros
name: Dubois, Bruno
name: Sarazin, Maria
name: Brandt, Jason
name: Albert, Marilyn
name: Marder, Karen
name: Bell, Karen L.
name: Honig, Lawrence S.
name: Wegesin, Domonick
name: Stern, Yaakov
Publisher: name: Columbia University
Year: 2004
Subjects: subject: Neurology
subject: Alzheimer's disease
subject: Movement disorders
subject: Neurosciences
subject: FOS: Clinical medicine

description: Background: Motor signs (MOSIs) are common in Alzheimer disease (AD) and may be associated with rates of cognitive decline, mortality, and cost of care. Objective: To describe the progression and identify predictors of individual MOSIs in AD. Methods: A cohort of 474 patients with AD at early stages was followed semiannually for up to 13.1 years (mean 3.6 years) in five centers in Europe and the United States. MOSIs were rated using a standardized portion of the Unified Parkinson's Disease Rating Scale. Overall, 3,030 visits/assessments of MOSIs (average 6.4/patient) were performed. Prevalence and incidence rates were calculated, and cumulative risk graphs were plotted for individual non-drug-induced MOSI domains. Rates of change over time taking into account potential covariates were also estimated. With use of each MOSI domain as outcome in Cox models, predictors of MOSI incidence were identified. Results: At least one MOSI was detected in 13% of patients at first examination and in 36% for the last evaluation. Total MOSI score increased at an annual rate of 3% of total possible score. Rates of annual change for speech/facial expression (4%), rigidity (2.45%), posture/gait (3.9%), and bradykinesia (3.75%) were of similar magnitude, and their occurrence increased from first (3 to 6%) to last (22 to 29%) evaluation. Tremor was less frequent throughout the course of the disease (4% at first and 7% at last evaluation) and worsened less (0.75% increase/year). Conclusions: Most motor signs occur frequently and progress rapidly in Alzheimer disease. Tremor is an exception in that it occurs less frequently and advances at slower rates.
Local and non-local measures of acceleration in cosmology
Creators: name: Bull, Philip
name: Clifton, Timothy
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Current cosmological observations, when interpreted within the framework of a homogeneous and isotropic Friedmann-Lemaitre-Robertson-Walker (FLRW) model, strongly suggest that the Universe is entering a period of accelerating expansion. This is often taken to mean that the expansion of space itself is accelerating. In a general spacetime, however, this is not necessarily true. We attempt to clarify this point by considering a handful of local and non-local measures of acceleration in a variety of inhomogeneous cosmological models. Each of the chosen measures corresponds to a theoretical or observational procedure that has previously been used to study acceleration in cosmology, and all measures reduce to the same quantity in the limit of exact spatial homogeneity and isotropy. In statistically homogeneous and isotropic spacetimes, we find that the acceleration inferred from observations of the distance-redshift relation is closely related to the acceleration of the spatially averaged universe, but does not necessarily bear any resemblance to the average of the local acceleration of spacetime itself. For inhomogeneous spacetimes that do not display statistical homogeneity and isotropy, however, we find little correlation between acceleration inferred from observations and the acceleration of the averaged spacetime. This shows that observations made in an inhomogeneous universe can imply acceleration without the existence of dark energy.
description: 19 pages, 10 figures. Several references added or amended, some minor clarifications made in the text
Mechanism of protein tyrosine phosphatase 1B inhibition by theaflavanoside IV isolated from methanolic extract of tea (Camellia sinensis) seed shells
Creators: name: Woo, Hyun Sim
name: Im, Hyeon Jeong
name: Kim, Jeong Yoon
name: Lee, Min-Sung
name: Kim, Dae Wook
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Inorganic Chemistry

description: Camellia sinensis (tea) seeds have been identified as potential sources of nutraceutical compounds. In this study, caffeine and theaflavanoside IV were annotated as the most abundant phytochemicals in the seed shells of C. sinensis. Both compound displayed potent inhibitions against protein tyrosine phosphatase 1B (PTP1B) with IC50 values of 37.9 ± 3.5 and 8.7 ± 1.1 µM, respectively. In the kinetic study, caffeine inhibited PTP1B with mixed type I mode, which prefers to bind to free enzyme. Theaflavanoside IV showed competitive and reversible simple slow-binding inhibition [k3 = 0.1 µM−1·min−1, k4 = 0.002 min−1, Kiapp = 0.0002 µM]. This is the first report on PTP1B-inhibitory activity of these compounds and their action mechanisms. These results suggest their potential in the development of antidiabetic agents.
Additional file 1 of Identification of risk factors for ewe mortality during the pregnancy and lambing period in extensively managed flocks
Creators: name: Flay, K. J.
name: Chen, A. S.
name: Yang, D. A.
name: Kenyon, P. R.
name: Ridler, A. L.
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology

description: Supplementary Material 1
Detection of isolated population III stars with the James Webb Space Telescope
Creators: name: Rydberg, Claes-Erik
name: Zackrisson, Erik
name: Lundqvist, Peter
name: Scott, Pat
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The first population III stars are predicted to form in minihalos at a redshift of approximately 10-30. The James Webb Space Telescope (JWST), tentatively scheduled for launch in 2018, will probably be able to detect some of the first galaxies, but whether it will also be able to detect the first stars remains more doubtful. Here, we explore the prospects of detecting an isolated population III star or a small cluster of population III stars down to redshift 2 in either lensed or unlensed fields. Our calculations are based on realistic stellar atmospheres and take into account the potential flux contribution from the surrounding HII region. We find that unlensed population III stars are beyond the reach of JWST, and that even lensed population III stars will be extremely difficult to detect. However, the main problem with the latter approach is not necessarily that the lensed stars are too faint, but that their surface number densities are too low. To detect even one population III star of 60 solar masses when pointing JWST through the galaxy cluster MACS J0717.5+3745, the lensing cluster with the largest Einstein radius detected so far, the cosmic star formation rate of population III stars would need to be approximately an order of magnitude higher than predicted by the most optimistic current models.
description: 8 pages, 6 figures, 1 table, published in MNRAS. The main change in version 2 is the inclusion of lower redshifts, down to 2. There was also one more SFR comparison model (Tornatore 2007) added
Y-system for Y=0 brane in planar AdS/CFT
Creators: name: Bajnok, Zoltan
name: Nepomechie, Rafael I.
name: Palla, Laszlo
name: Suzuki, Ryo
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The spectrum of open strings with integrable Y=0 brane boundary conditions is analyzed in planar AdS/CFT. We give evidence that it can be described by the same Y-system that governs the spectrum of closed strings in AdS_5xS^5, except with different asymptotic and analytical properties. We determine the asymptotic solution of the Y-system that is consistent both with boundary asymptotic Bethe ansatz and boundary Luscher corrections.
description: 25 pages, minor corrections, references added