cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Dytaster semispinosus
Creators: name: Jangoux, Michel
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Paxillosida
Astropectinidae
Dytaster
Dytaster semispinosus

description: semispinosus Perrier, 1894, Crenaster
Crenaster semispinosus Perrier, 1894: 307.
Dytaster semispinosus ‒ Clark & Downey 1992: 55.
CURRENT STATUS. — Dytaster semispinosus (Perrier, 1894).
TYPE MATERIAL. — Atlantic Ocean • 1 syntype; station 137; Talisman expedition; 1883; 44°29’N, 15°22’W; depth 4975 m; MNHN-IE-2014-160 • 1 syntype, same as for preceding;MNHN- IE-2014-368.
description: Published as part of Jangoux, Michel, 2022, The type specimens of extant asteroids (Echinodermata) in the Muséum national d'Histoire naturelle of Paris, pp. 259-334 in Zoosystema 44 (11) on pages 314-315, DOI: 10.5252/zoosystema2022v44a11, http://zenodo.org/record/6616817
Parton distributions in the proton and pion
Creators: name: Alberg, Mary
name: Henley, Ernest M.
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We use detailed balance for a hadron composed of quark and gluon Fock states to obtain parton distributions in the proton and pion on the basis of a simple statistical model.
description: 13 pages, 5 figures
Noise-assisted preparation of entangled atoms
Creators: name: Yi, X. X.
name: Yu, C. S.
name: Zhou, L.
name: Song, H. S.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We discuss the generation of entangled states of two two-level atoms inside an optical cavity. The cavity mode is supposed to be coupled to a white noise with adjustable intensity. We describe how the entanglement between the atoms inside the cavity arise in such a situation. The entanglement is maximized for intermediate values of the noise intensity, while it is a monotonic function of the spontaneous rate. This resembles the phenomenon of stochastic resonance and sheds more light on the idea to exploit white noise in quantum information processing.
description: 4 pages, 4 figures
title: Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´ÐµÑÐ°Ð»Ð¸ Â«Ð ÑÑÐ°Ð³ Ð¿ÑÐ°Ð²ÑÐ¹Â»
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Analysis of the technological process for manufacturing the part "Right Lever"
Creators: name: ÐÑÑÑÐºÐ¾Ð², ÐÑÑÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2025
Subjects: Ð´ÐµÑÐ°Ð»Ñ
ÑÑÑÐ°Ð³ Ð¿ÑÐ°Ð²ÑÐ¹
ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ°
ÑÐ°ÑÑÑÐ¸ÑÐ°ÑÑ
ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ°. ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ
Ð»Ð¸ÑÑÐµ Ð¿Ð¾Ð´ Ð´Ð°Ð²Ð»ÐµÐ½Ð¸ÐµÐ¼
Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ°
ÑÐ¾ÑÐ½Ð¾ÑÑÑ
ÑÑÐµÐ·ÐµÑÐ½ÑÐ¹ ÑÐ¿Ñ
part
right lever
development
calculate
technological process
pressure casting
workpiece
accuracy
cnc milling

description: Ð ÑÐ°Ð±Ð¾ÑÐµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ñ ÑÑÐ°Ð¿Ñ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²Ð° Ð´ÐµÑÐ°Ð»Ð¸, Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ñ ÑÐ°ÑÑÐµÑÑ Ð¼Ð°ÑÑÑ Ð´ÐµÑÐ°Ð»Ð¸, ÑÐ°Ðº Ð¸ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸. Ð¢Ð°ÐºÐ¶Ðµ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð° Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð°Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ°Ñ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ñ. Ð ÑÐ¾Ð´Ðµ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ» Ð¾ÑÑÑÐµÑÑÐ²Ð»ÑÐ½ Ð²ÑÐ±Ð¾Ñ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¾ÑÐ½Ð°ÑÑÐºÐ¸. ÐÐ¾Ð´Ð¾Ð±ÑÐ°Ð½Ñ ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐµÐ·Ð°Ð½Ð¸Ñ Ð¸ ÑÐ¾ÑÑÐ°Ð²Ð»ÐµÐ½ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ. ÐÑÐ¾Ð¼Ðµ ÑÐ¾Ð³Ð¾ Ð±Ñ ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½ Ð¸ ÑÐ¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½ ÑÐ°ÑÐ¾Ð½Ð½ÑÐ¹ Ð¿ÑÐ¸Ð·Ð¼Ð°ÑÐ¸ÑÐµÑÐºÐ¸Ð¹ ÑÐµÐ·ÐµÑ.
description: The work describes the stages of production of the part, including calculations of the mass of both the part and the blank. Necessary technological documentation has also been prepared. In the course of the work, the selection of equipment and the development of tooling were carried out. Cutting modes were selected, and the technological process was compiled. Additionally, a shaped prismatic cutter was calculated and designed.
Cosmic footballs from superrotations
Creators: name: Adjei, Eugene
name: Donnelly, William
name: Py, Victor
name: Speranza, Antony J.
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Superrotations arise from singular vector fields on the celestial sphere in asymptotically flat space, and their finite integrated versions have been argued by Strominger and Zhiboedov to insert cosmic strings into the spacetime. In this work, we argue for an alternative definition of the action of superrotations on Minkowski space that avoids introducing any defects. This involves realizing the finite superrotation not as a diffeomorphism between spaces, but as a mapping of Minkowski space to itself that may be multivalued or non-surjective. This eliminates any defects in the bulk spacetime at the expense of allowing for defects in the boundary celestial sphere metric. We further explore the geometry of the spatial surfaces in the superrotated spaces, and note that they intersect null infinity at the singularity of the superrotation, causing a breakdown in the large $r$ asymptotic expansion there. To determine how these surfaces embed into Minkowski space, a derivation of the finite superrotation transformation is presented in both Bondi and Newman-Unti gauges. The latter is particularly interesting, since the superrotations are shown to preserve the hyperbolic slicing of Minkowski space in Newman-Unti gauge, and this gauge also provides a means for extending the geometry beyond the Bondi coordinate patch. We argue that the new interpretation for the action of superrotations on spacetime motivates consideration of a wider class of celestial sphere metrics and asymptotic symmetry groups.
description: 24+8 pages, 8 figures
An outlook of docking analysis and structure-activity relationship of pyrimidine-based analogues as EGFR inhibitors against non-small cell lung cancer (NSCLC)
Creators: name: Pal, Rohit
name: Teli, Ghanshyam
name: Sengupta, Sindhuja
name: Maji, Lalmohan
name: Matada, Gurubasavaraja Swamy Purawarga
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer

description: Almost 80% of lung cancer diagnoses each year correspond to non-small cell lung cancer (NSCLC). The percentage of NSCLC with EGFR overexpression ranges from 40% to 89%, with squamous tumors showing the greatest rates (89%) and adenocarcinomas showing the lowest rates (41%). Therefore, in NSCLC therapy, blocking the EGFR-driven pathway by inhibiting the intracellular tyrosine kinase domain of EGFR has exhibited significant improvement. In this view, several small molecules particularly pyrimidine/fused pyrimidine scaffolds were intended for molecular hybridization to develop EGFR-TK inhibitors. However, the associated limitation such as resistance and genetic mutation along with adverse effects, constrained the long-term treatment and effectiveness of such medication. Therefore, in recent years, pyrimidine derivatives were uncovered as potential EGFR TKIs. The present review summarised the research progress of EGFR TKIs to dazed structure-activity relationship, biological evaluation, and comparative docking studies of pyrimidine compounds. We have added the comparative docking analysis followed by the molecular simulation study against the four different PDBs of EGFR to strengthen the already existing research. Docking analysis unfolded that compound 14 resulted as noticeable with all different PDB and managed to interact with some of the crucial amino acid residues. From a future perspective, researchers must develop a more selective inhibitor, that can selectively target the mutation. Our review will support medicinal chemists in the direction of the development of novel pyrimidine-based EGFR TKIs. Communicated by Ramaswamy H. Sarma
Calculated solar-neutrino capture rate for a radiochemical 205 Tl-based solar-neutrino detector
Creators: name: Kostensalo, Joel
name: Suhonen, Jouni
name: Zuber, Kai
Publisher: name: arXiv
Year: 2019
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Radiochemical experiments for low-energy solar-neutrino detection have been making headlines by exploiting the isotopes \iso{Cl}{37} and \iso{Ga}{71}. Such a very low-threshold measurement of this type can also be performed using \iso{Tl}{205}, which has been considered for decades for this purpose. A unique feature of this detector nucleus is the integration is the solar-neutrino flux over millions of years owing to its long-living daughter \iso{Pb}{205}. In this study we have calculated for the first time the cross section for the charged-current solar-neutrino scattering off \iso{Tl}{205}. Taking into account the solar-model-predicted neutrino fluxes and the electron-neutrino survival probabilities, a solar-neutrino capture rate of 62.2 $\pm 8.6$ SNU is determined, a value significantly smaller than in previous estimates.
description: 3 pages, 4 figures
The Initial Value Problem Using Metric and Extrinsic Curvature
Creators: name: York, James W.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The initial value problem is introduced after a thorough review of the essential geometry. The initial value equations are put into elliptic form using both conformal transformations and a treatment of the extrinsic curvature introduced recently. This use of the metric and the extrinsic curvature is manifestly equivalent to the author's conformal thin sandwich formulation. Therefore, the reformulation of the constraints as an elliptic system by use of conformal techniques is complete.
description: 10 pages, to appear in the Proceedings of the Tenth Marcel Grossmann Meeting on General Relativity
Additional file 1 of Respiratory motion-compensated high-resolution 3D whole-heart T1ρ mapping
Creators: name: Haikun Qi
name: Bustin, Aurelien
name: Kuestner, Thomas
name: Hajhosseiny, Reza
name: Gastao Cruz
name: Kunze, Karl
name: Radhouene Neji
name: Botnar, René
name: Prieto, Claudia
Publisher: name: figshare
Year: 2020
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1: Figure S1. Reconstructed T1ρ image and T1ρ map of a heathy subject with undersampling factors of 3.8 and 5. The 5x accelerated data was obtained by retrospective undersampling of the data acquired with acceleration factor 3.8. Slight loss of reconstruction and mapping quality can be observed for undersampling factor 5, indicated by the white arrows.
Non-Markovian stochastic processes and the wave-like properties of matter
Creators: name: Pinheiro, Mario J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Classical Physics (physics.class-ph)
subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: A non-markovian stochastic model is shown to lead to a universal relationship between particle's energy, driven frequency and a frequency of interaction with the medium. It is briefly discussed the possible relevance of this general structure to various phenomena in the context of the formation of patterns in granular media, computation in a Brownian-type computer and the Haisch-Rueda-Puthoff inertial mass theory.
description: 11 pages, no figures
MOESM8 of Comparative transcriptome analysis reveals the response mechanism of Cf-16-mediated resistance to Cladosporium fulvum infection in tomato
Creators: name: Zhang, Dongye
name: Bao, Yufang
name: Sun, Yaoguang
name: Yang, Huanhuan
name: Zhao, Tingting
name: Li, Huijia
name: Du, Chong
name: Jiang, Jingbin
name: Li, Jingfu
name: Xie, Libo
name: Xu, Xiangyang
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology

description: Additional file 8: Table S8. Common DEGs in the significantly enriched KEGG pathway “Plant-pathogen interaction” between the MM_4dpi-vs-Cf_4dpi and CK_Cf_4dpi-vs-Cf_4dpi comparisons.
Higgsless Theory of Electroweak Symmetry Breaking from Warped Space
Creators: name: Nomura, Yasunori
Publisher: name: arXiv
Year: 2003
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study a theory of electroweak symmetry breaking without a Higgs boson, recently suggested by Csaki et al. The theory is formulated in 5D warped space with the gauge bosons and matter fields propagating in the bulk. In the 4D dual picture, the theory appears as the standard model without a Higgs field, but with an extra gauge group G which becomes strong at the TeV scale. The strong dynamics of G breaks the electroweak symmetry, giving the masses for the W and Z bosons and the quarks and leptons. We study corrections in 5D which are logarithmically enhanced by the large mass ratio between the Planck and weak scales, and show that they do not destroy the structure of the electroweak gauge sector at the leading order. We introduce a new parameter, the ratio between the two bulk gauge couplings, into the theory and find that it allows us to control the scale of new physics. We also present a potentially realistic theory accommodating quarks and leptons and discuss its implications, including the violation of universality in the W and Z boson couplings to matter and the spectrum of the Kaluza-Klein excitations of the gauge bosons. The theory reproduces many successful features of the standard model, although some cancellations may still be needed to satisfy constraints from the precision electroweak data.
description: 17 pages, Latex; important correction in discussions on effects from brane terms, reference added
New radiative transfer models for obscuring tori in active galaxies
Creators: name: van Bemmel, I. M.
name: Dullemond, C. P.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Two-dimensional radiative transfer is employed to obtain the broad-band infrared spectrum of active galaxies. In the models we vary the geometry and size of the obscuring medium, the surface density, the opacity and the grain size distribution. Resulting spectral energy distributions are constructed for different orientations of the toroid. Colour-colour comparisons with observational data are consistent with previous observations that the emission longward of 60 micron is produced by star-formation and unrelated to the presence of an obscuring torus. We also find that the toroid cannot be flat, but is rather conical or flaring. The density is most likely constant with radius, and the size is relatively large with an inner radius around 10 pc. A direct comparison with radio galaxy Cygnus A yields a best fit for a conical disk with constant surface density, and a size from 10 to 30 pc assuming the far-infrared emission is due to star-formation in the host galaxy.
description: 20 pages including 15 figures, accepted for publication by A&A
Integrated in-silico and in-vitro assessments of HDAC6 inhibitor efficacy in mitigating amyloid beta pathology in Alzheimer’s disease
Creators: name: Choudhary, Gajendra
name: Prajapat, Manisha
name: Kaur, Gurjeet
name: Singh, Harvinder
name: Mahendiratta, Saniya
name: Prakash, Ajay
name: Medhi, Bikash
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Information Systems not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Infectious Diseases
subject: FOS: Health sciences

description: Alzheimer’s disease, marked by memory loss and cognitive decline, is associated with amyloid-beta (Aβ) peptide accumulation in the brain. The enzyme neprilysin (NEP), crucial for Aβ degradation, decreases with age and in sporadic Alzheimer’s disease, leading to increased Aβ build-up. This study hypothesized the targeting of enzyme HDAC6, believed to influence NEP activity. An in-silico study was conducted using an FDA-approved drug database, with the focus on their interaction with the HDAC6 structure. Among tested ligands, Panobinostat showed the most favourable interaction with HDAC6. In-vitro experiments on the SH-SY5Y neuronal cell line confirmed these findings, with Panobinostat inhibiting HDAC6, enhancing NEP levels, and reducing Aβ load. The study suggests Panobinostat as a potential Alzheimer’s therapeutic agent, mitigating Aβ accumulation via NEP upregulation. Further research is required for comprehensive understanding and validation. Communicated by Ramaswamy H. Sarma
Additional file 1 of Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study
Creators: name: Chabriat, Hugues
name: Bassetti, Claudio
name: Marx, Ute
name: FranÃ§Oise Picarel-Blanchot
name: Sors, Aurore
name: Celine Gruget
name: Saba, Barbara
name: Wattez, Marine
name: Marie-Laure Audoli
name: Hermann, Dirk
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Science Policy

description: Additional file 1. SPIRIT 2013 checklist: Recommended items to address in a clinical trial protocol and related documents.
Luidia senegalensis
Creators: name: Jangoux, Michel
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Paxillosida
Luidiidae
Luidia
Luidia senegalensis

description: senegalensis Lamarck, 1816, Asterias
Asterias senegalensis Lamarck, 1816: 567.
Luidia senegalensis ‒ Clark & Downey 1992: 21.
CURRENT STATUS. — Luidia senegalensis (Lamarck, 1816).
TYPE MATERIAL. — Senegal • 2 syntypes; Adanson leg.; MNHN- IE-2014-655.
REMARKS
Except for the two aforesaid syntypes, the species Luidia senegalensis was never reported from African coasts and the type locality should be wrong, as it is the case with several Adanson localities (see Madsen 1950: 205). Luidia senegalensis is a shallow water species from western Atlantic (Florida to north of Brazil).
Photographs of a syntype of A. senegalensis is presented in Jangoux (2021: 244).
description: Published as part of Jangoux, Michel, 2022, The type specimens of extant asteroids (Echinodermata) in the Muséum national d'Histoire naturelle of Paris, pp. 259-334 in Zoosystema 44 (11) on page 315, DOI: 10.5252/zoosystema2022v44a11, http://zenodo.org/record/6616817
Roweis Discriminant Analysis: A Generalized Subspace Learning Method
Creators: name: Ghojogh, Benyamin
name: Karray, Fakhri
name: Crowley, Mark
Publisher: name: arXiv
Year: 2019
Subjects: subject: Machine Learning (stat.ML)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: We present a new method which generalizes subspace learning based on eigenvalue and generalized eigenvalue problems. This method, Roweis Discriminant Analysis (RDA), is named after Sam Roweis to whom the field of subspace learning owes significantly. RDA is a family of infinite number of algorithms where Principal Component Analysis (PCA), Supervised PCA (SPCA), and Fisher Discriminant Analysis (FDA) are special cases. One of the extreme special cases, which we name Double Supervised Discriminant Analysis (DSDA), uses the labels twice; it is novel and has not appeared elsewhere. We propose a dual for RDA for some special cases. We also propose kernel RDA, generalizing kernel PCA, kernel SPCA, and kernel FDA, using both dual RDA and representation theory. Our theoretical analysis explains previously known facts such as why SPCA can use regression but FDA cannot, why PCA and SPCA have duals but FDA does not, why kernel PCA and kernel SPCA use kernel trick but kernel FDA does not, and why PCA is the best linear method for reconstruction. Roweisfaces and kernel Roweisfaces are also proposed generalizing eigenfaces, Fisherfaces, supervised eigenfaces, and their kernel variants. We also report experiments showing the effectiveness of RDA and kernel RDA on some benchmark datasets.
description: This is the paper for the methods Roweis Discriminant Analysis (RDA), dual RDA, kernel RDA, and Roweisfaces. This is in memory of Sam Roweis (rest in peace) to whom subspace and manifold learning owes significantly
Additional file 1 of Respiratory system compliance at the same PEEP level is similar in COVID and non-COVID ARDS
Creators: name: Fusina, Federica
name: Albani, Filippo
name: Crisci, Serena
name: Morandi, Alessandro
name: Tansini, Francesca
name: Beschi, Rasula
name: Rosano, Antonio
name: Natalini, Giuseppe
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Science Policy
subject: Hematology

description: Additional file 1. Supplementary Material.
Additional file 1 of D-chiro-inositol effectively counteracts endometriosis in a mouse model
Creators: name: Placidi, Martina
name: Casoli, Giovanni
name: Vergara, Teresa
name: Bianchi, Andrea
name: Cocciolone, Domenica
name: Zaccardi, Silvia
name: Macchiarelli, Guido
name: Palmerini, Maria Grazia
name: Tatone, Carla
name: Bevilacqua, Arturo
name: Di Emidio, Giovanna
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences

description: Supplementary material 1.
Survey of Fruit and Tree Nut Use by Frozen Dessert Manufacturers
Creators: name: Reese, Robert B.
name: Reese, Robert B.
Publisher: name: Unknown
Year: 1956
Subjects: subject: Crop Production/Industries
subject: Food Consumption/Nutrition/Food Safety
subject: Marketing
subject: FOS: Economics and business
subject: Research and Development/Tech Change/Emerging Technologies

description: Excerpts from the report: Increasing quantities of agricultural products are being marketed in frozen form. What is the present and potential impact of this increase upon agricultural marketing? This study of fruit use by ice cream manufacturers is one of a series to measure the relative size and nature of each of the major markets for frozen fruits and berries. More than 65 percent of the 1953 frozen fruit and berry pack, excluding frozen Juice concentrates, was in the large -sized containers used by food manufacturers and institutional trade. The bulk of this pack was consumed by ice cream manufacturers, preservers, pie bakers, restaurants, and cafeterias. The aim of this survey was to answer the following questions: 1. How much frozen fruit is used in frozen dessert manufacturing? 2. How does this volume of frozen fruits compare with the quantities of fresh and canned fruits used? 3. What suggestions does this industry offer for improving frozen fruits to meet its needs? 4. What is the outlook for future use of frozen fruits in frozen dessert manufacture?
Testing the bounds on quantum probabilities
Creators: name: Filipp, Stefan
name: Svozil, Karl
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Bounds on quantum probabilities and expectation values are derived for experimental setups associated with Bell-type inequalities. In analogy to the classical bounds, the quantum limits are experimentally testable and therefore serve as criteria for the validity of quantum mechanics.
description: 9 pages, Revtex
Application of a newly-developed cynomolgus macaque BiTE-mediated cytotoxic T-lymphocyte activity assay to various immunomodulatory agents in vitro
Creators: name: Frank, Brendon
name: Guo, Hao
name: Lebrec, Hervé
name: Wang, Xiaoting
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The immunotoxic potential of drug candidates is assessed through the examination of results from a variety of in vitro and in vivo immunophenotyping and functional study endpoints in pre-clinical studies. CD8+ cytotoxic T-lymphocyte (CTL) activity impairment by immunosuppressive agents is recognized to be a potentiating factor for decreased antiviral defense and increased cancer risk. A bi-specific T-cell engager (BiTE®)-mediated CTL activity assay that applies to ex vivo experimentation in non-human primates in the context of toxicology studies was successfully developed and applied in cynomolgus monkey regulatory studies. While an ex vivo analysis conducted in the context of repeat-dose toxicology studies focuses on the long-term impact on CTL function, an in vitro assay with the same experimental design captures acute effects in the presence of the test article. Here, the in vitro assay was applied to a list of drugs with known clinical immunomodulatory impact to understand the applicability of the assay. The results showed this assay was sensitive to a wide range of immunosuppressants directly targeting cell-intrinsic signaling pathways in activated CTL. However, agents executing immuno-modulation through inhibiting cytokines/cytokine receptors, co-stimulatory molecules, and cell adhesion and migration pathways did not impair the CTL activity in this short-term in vitro culture. In addition, anti-PD-1/PD-L1 immune checkpoint blockers enhanced the CTL activity. Taken together, the results here demonstrate that in concordance with their mechanism of action, the in vitro BiTE®-mediated CTL assay is applicable and sensitive to immunomodulatory agents acting via a variety of mechanisms.
Shocklets in the Comet Halley Plasma
Creators: name: Naeem, Ismat
name: Ehsan, Zahida
name: Mirza, A. M.
name: Murtaza, G.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: FOS: Physical sciences

description: Dust acoustic (DA) waves evolving into shocklets are investigated in the Comet Halley plasma system relaxing to Maxwellian, Kappa and Cairns distributions. Here dynamics of dust is described by the fully nonlinear continuity and momentum equations. A set of two characteristic wave nonlinear equations is obtained and numerically solved to examine the DA solitary pulse which develops into oscillatory shocklets with the course of time such as at time τ=0, symmetric solitary pulses are formed, which develop into oscillatory shocklets. It has been observed that variation in superthermality strongly affects the profiles of nonlinear DA structures in terms of negative potential, dust velocity and density.
Additional file 1 of Comparison of DNA methylation profiles from saliva in Coeliac disease and non-coeliac disease individuals
Creators: name: Nerissa Hearn
name: Chiu, Christine
name: Lind, Joanne
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Marine Biology

description: Additional file 1. Study Questionnaire. This questionnaire was administered to participants on recruitment to enable collection of sociodemographic and health-related information.
MOESM1 of The complete mitochondrial genome of Taxus cuspidata (Taxaceae): eight protein-coding genes have transferred to the nuclear genome
Creators: name: Kan, Sheng-Long
name: Shen, Ting-Ting
name: Gong, Ping
name: Ran, Jin-Hua
name: Wang, Xiao-Quan
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Additional file 1: Table S1. Primers used in this study.
Astropecten irregularis
Creators: name: Jangoux, Michel
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Echinodermata
Asteroidea
Paxillosida
Astropectinidae
Astropecten
Astropecten irregularis

description: serratus Müller & Troschel, 1842, Astropecten
Astropecten serratus Müller & Troschel, 1842: 72.
Astropecten irregularis ‒ Clark 1989: 268.
CURRENT STATUS. — Astropecten irregularis (Pennant, 1777).
TYPE MATERIAL. — Mediterranea • 2 syntypes; MNHN-IE-2014-13.
description: Published as part of Jangoux, Michel, 2022, The type specimens of extant asteroids (Echinodermata) in the Muséum national d'Histoire naturelle of Paris, pp. 259-334 in Zoosystema 44 (11) on page 315, DOI: 10.5252/zoosystema2022v44a11, http://zenodo.org/record/6616817
In silico and immunoinformatics based multiepitope subunit vaccine design for protection against visceral leishmaniasis
Creators: name: Bhowmik, Deep
name: Bhuyan, Achyut
name: Gunalan, Seshan
name: Kothandan, Gugan
name: Kumar, Diwakar
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Physical Sciences not elsewhere classified
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Visceral leishmaniasis (VL) is a vector-borne neglected tropical protozoan disease with high fatality and no certified vaccine. Conventional vaccine preparation is challenging and tedious. Here in this work, we created a global multiepitope subunit vaccination against VL utilizing innovative immunoinformatics technique based on the extensively conserved epitopic regions of the PrimPol protein of Leishmania donovani consisting of four subunits which were analyzed and studied, out of which DNA primase large subunit and DNA polymerase α subunit B were evaluated as antigens by Vaxijen 2.0. The multiepitope vaccine design includes a single adjuvant β-defensins, eight CTL epitopes, eight HTL epitopes, seven linear BCL epitopes and one discontinuous BCL epitope to induce innate, cellular and humoral immune responses against VL. The Expasy ProtParam tool characterized the physiochemical parameters of the vaccine. At the same time, SOLpro evaluated our vaccine constructs to be soluble upon expression. We also modeled the stable tertiary structure of our vaccine construct through Robetta modeling for molecular docking studies with toll-like receptor proteins through HADDOCK 2.4. Simulations based on molecular dynamics revealed an intact vaccine and TLR8 complex, supporting our vaccine design’s immunogenicity. Also, the immune simulation of our vaccine by the C-ImmSim server demonstrated the potency of the multiepitope vaccine construct to induce proper immune response for host defense. Codon optimization and in silico cloning of our vaccine further assured high expression. The outcomes of our study on multiepitope vaccine design significantly produced a potential candidate against VL and can potentially eradicate the disease in the future after clinical investigations. Communicated by Ramaswamy H. Sarma
The Effect of Land Fraction and Host Star Spectral Energy Distribution on the Planetary Albedo of Terrestrial Worlds
Creators: name: Rushby, Andrew J.
name: Shields, Aomawa L.
name: Joshi, Manoj
Publisher: name: arXiv
Year: 2019
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The energy balance and climate of planets can be affected by the reflective properties of their land, ocean, and frozen surfaces. Here we investigate the effect of host star spectral energy distribution (SED) on the albedo of these surfaces using a one-dimensional (1-D) energy balance model (EBM). Incorporating spectra of M-, K-, G- and F-dwarf stars, we determined the effect of varying fractional and latitudinal distribution of land and ocean surfaces as a function of host star SED on the overall planetary albedo, climate, and ice-albedo feedback response. While noting that the spatial distribution of land masses on a given planet will have an effect on the overall planetary energy balance, we find that terrestrial planets with higher average land/ocean fractions are relatively cooler and have higher albedo regardless of star type. For Earth-like planets orbiting M-dwarf stars the increased absorption of water ice in the near-infrared (NIR), where M-dwarf stars emit much of their energy, resulted in warmer global mean surface temperatures, ice lines at higher latitudes, and increased climate stability as the ice-albedo feedback became negative at high land fractions. Conversely, planets covered largely by ocean, and especially those orbiting bright stars, had a considerably different energy balance due to the contrast between the reflective land and the absorptive ocean surface, which in turn resulted in warmer average surface temperatures than land-covered planets and a stronger potential ice-albedo feedback. While dependent on the properties of individual planetary systems, our results place so constraints on a range of climate states of terrestrial exoplanets based on albedo and incident flux.
description: 12 pages, 4 figures
MOESM9 of Comparative transcriptome analysis reveals the response mechanism of Cf-16-mediated resistance to Cladosporium fulvum infection in tomato
Creators: name: Zhang, Dongye
name: Bao, Yufang
name: Sun, Yaoguang
name: Yang, Huanhuan
name: Zhao, Tingting
name: Li, Huijia
name: Du, Chong
name: Jiang, Jingbin
name: Li, Jingfu
name: Xie, Libo
name: Xu, Xiangyang
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology

description: Additional file 9: Figure S1. Classification of raw reads from different samples.
Why the Theta+ is seen in some experiments and not in others - a possible explanation
Creators: name: Karliner, Marek
name: Lipkin, Harry J.
Publisher: name: arXiv
Year: 2004
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: The contradiction between evidence for and against the existence of the Theta+ pentaquark might be resolved if it only appears as a result of a particular production mechanism which is present in some experiments and absent in others. We examine the implications of Theta+ production via decay of a cryptoexotic N* resonance with a mass of about 2.4 GeV corresponding to a peak in the experimental data for the invariant mass of the (Theta+,K-) system. Further experimental checks are suggested.
description: An experimental reference added. 8 pages, LaTeX, no figures
Do Trading Stamps Affect Food Costs?
Creators: name: Agricultural Marketing Service, Market Organization
name: Agricultural Marketing Service, Market Organization
Publisher: name: Unknown
Year: 1957
Subjects: subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Marketing
subject: FOS: Economics and business

description: Excerpts from the report Preface: Food prices reached a near-record level in the third quarter of 1956. This advance was part of a broad increase in living expenses which reached a new high. Public opinion was focused on the increase and consumers want to know why food costs so much. Studies by the U. S. Department of Agriculture show that more than half of the retail price of food goes for processing and distribution. Because of this, any changes that may result in further increase in costs come in for close attention. In recent years a number of competitive practices have developed or been expanded at the retail level which may affect the cost of retailing. One of the most striking of these is the phenomenal expansion in use of food trading stamps. Because of the importance of these developments the Agricultural Marketing Service has undertaken a study of the effects of the use of food trading stamps and associated practices on marketing organization, costs, and efficiency. This first report seeks only to explain the basic characteristics of trading stamp plans, to review and discuss available information relating to the development and use of the stamps, and to consider some of the relevant issues and economic problems facing retailers and consumers as a result of the widespread use of these stamps.
Unidentified EGRET sources in the Galaxy
Creators: name: Grenier, I. A.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Identifying gamma-ray sources in the Galaxy is hampered by their poor localization, source confusion, and the large variety of potential emitters. Neutron stars and their environment offer various ways to power gamma-ray sources: pulsed emission from the open magnetosphere and unpulsed gamma rays from the wind nebula and from the cosmic rays accelerated in the supernova remnant. While the latter still awaits confirmation, new candidate associations bring forward the importance of 10-kyr old pulsars as GeV sources, with a diversity that will help constrain the acceleration mechanisms near the pulsar and in the wind. Theoretical interest in the gamma-ray activity of X-ray binaries and micro-quasars has also been revived by the emergence of a subset of variable sources in the inner Galaxy and another one in the halo.
description: 8 pages, Proc. of the Texas Symposium, 2002, Florence, Italy
Additional file 2 of Comparison of DNA methylation profiles from saliva in Coeliac disease and non-coeliac disease individuals
Creators: name: Nerissa Hearn
name: Chiu, Christine
name: Lind, Joanne
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Marine Biology
subject: Cancer

description: Additional file 2. Methods. Contains primer sequences used for Sanger sequencing and Bisulphite pyrosequencing.
Additional file 1 of Modular evolution of secretion systems and virulence plasmids in a bacterial species complex
Creators: name: Chou, Lin
name: Lin, Yu-Chen
name: Haryono, Mindia
name: Santos, Mary Nia M.
name: Cho, Shu-Ting
name: Weisberg, Alexandra J.
name: Wu, Chih-Feng
name: Chang, Jeff H.
name: Lai, Erh-Min
name: Kuo, Chih-Horng
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Gene content dissimilarity among the Agrobacterium genomes. (A) and (B): principal coordinate analysis with and without the outgroup A. larrymoorei, respectively. The % variance explained by each axis is provided in parentheses. (C) and (D): hierarchical clustering with and without the outgroup A. larrymoorei, respectively. Figure S2. Global alignment of the linear chromosomes. Locations of T6SS-hcp operons and vgrG homologs are labeled. Figure S3. Logo plots of the putative protein domains identified among vgrG homologs. For each domain, the length and the number of homologs with the domain is labeled. Domain 1 is the only domain with a corresponding database entry (TIGR03361). Figure S4. Predicted structures of VgrG homologs. Regions are colored according to the scheme used in the domain analysis (Fig. 3). The chain D of PA0091 VgrG1 (PDB identifier: 4MTK) from Pseudomonas aeruginosa was selected as the template. The C-terminal parts that could not be confidently inferred are omitted. In all cases, the coverage (i.e., percentage of the sequence included in the structure prediction) are at least 75%, the sequence identity to the template is at least 30% and the confidence score is 100%. Figure S5. Maximum likelihood phylogenies of vgrG-associated domains. (A) Domain 1 (TIGR03361; VI_Rhs_Vgr super family), (B) Domain 2 (unknown function), and (C) Domain 3 (unknown function). Figure S6. Principal coordinate analysis of gene content among the putative pTi analyzed. Figure S7. Maximum likelihood phylogeny of pTi based on the concatenated alignment of shared single-copy genes. (A) All of the 20 pTi sequences analyzed; 21 core genes and 8534 aligned amino acid sites. (B) Excluding the two novel pTi; 40 core genes and 15,473 aligned amino acid sites, all branches received > 80% bootstrap support. Figure S8. Tomato tumor assay of strains 12D1, CFBP4996, and CFBP5473. Mock was inoculated with sterilized water as a negative control and strain C58 was included as a positive control. Strain 12D1 harbors a plasmid with opine transporter and catabolism genes but lacks vir regulon genes and identifiable T-DNA. CFBP4996 and CFBP5473 harbor novel types of putative tumor-inducing plasmids (pTi). (A) Tomato stems at three weeks after inoculation. Scale bar: 0.25 cm. (B) Weight distribution of five biological replicates (1-cm segments of the stem centered at the inoculation site). The letters indicate ANOVA results. Figure S9. Gene organization of the vir regulons on pTi. Syntenic regions are indicated by grey blocks. The virulence (vir) genes are highlighted in red, the conjugation (tra) genes are highlighted in yellow, and other genes are plotted in white.
Radio Loud AGN in the Context of the Eigenvector 1 Parameter Space
Creators: name: Sulentic, J. W.
name: Zamfir, S.
name: Marziani, P.
name: Bachev, R.
name: Calvani, M.
name: Dultzin-Hacyan, D.
Publisher: name: arXiv
Year: 2003
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We consider the properties of radio-loud (RL) AGN in the context of the Eigenvector 1 (E1) parameter space. RL sources show a restricted E1 parameter space occupation relative to the radio-quiet (RQ) majority. The Fanaroff-Riley II ``parent population'' of relatively un-boosted RL sources (median radio/optical flux ratio ~490) shows the most restricted occupation. RL sources have different broad line properties (and inferred black hole masses and Eddington ratios). FWHM H_beta for the broad line component in RL sources are at least twice as large as the RQ majority. The average broad FeII emission line strength is also about half that for RQ sources. Our sample suggests that the RL cutoff occurs near R_k=70 or logP(6cm)=32.0 ergs/s/Hz. Sources below this cutoff are RQ although we cannot rule out the existence of a distinct intermediate population. We show that the Doppler boosted core-dominated RL sources (median flux ratio ~1000) lie towards smaller FWHM(H_beta_bc) and stronger FeII in E1 as expected if the lines arise in an accretion disk. Our subsample of superluminal sources, with orientation inferred from the synchrotron self Compton model, reinforce this general E1 trend and allow us to estimate the role of source orientation in driving E1 domain occupation.
description: 9 pages, 3 figures, accepted for publication in ApJL
Karmarkar scalar condition
Creators: name: Ospino, J.
name: Nunez, L. A.
Publisher: name: arXiv
Year: 2020
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: In this work we present the Karmarkar condition in terms of the structure scalars obtained from the orthogonal decomposition of the Riemann tensor. This the new expression becomes an algebraic relation among the physical variables, and not a differential equation between the metric coefficients. By using the Karmarkar scalar condition we implement a method to obtain all possible embedding class I static spherical solutions, provided the energy density profile is given. We also analyse the dynamic adiabatic case and show the incompatibility of the Kamarkar condition with several commonly assumed simplifications to the study of gravitational collapse. Finally, we consider the dissipative dynamic Karmarkar collapse and find a new solution family.
description: 13 pages, 1 figures. arXiv admin note: text overlap with arXiv:1810.03059
Pseudo-reality and pseudo-adjointness of Hamiltonians
Creators: name: Ahmed, Zafar
Publisher: name: arXiv
Year: 2003
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We define pseudo-reality and pseudo-adjointness of a Hamiltonian, $H$, as $ρH ρ^{-1}=H^\ast$ and $μH μ^{-1}=H^\prime$, respectively. We prove that the former yields the {\it necessary} condition for spectrum to be real whereas the latter helps in fixing a definition for inner-product of the eigenstates. Here we separate out adjointness of an operator from its Hermitian-adjointness. It turns out that a Hamiltonian possessing real spectrum is first pseudo-real, further it could be Hermitian, PT-symmetric or pseudo-Hermitian.
description: No Figures, 11 pages