cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Streaming Velocity Effects on the Post-reionization 21 cm Baryon Acoustic Oscillation Signal
Creators: name: Long, Heyang
name: Givans, Jahmour J.
name: Hirata, Christopher M.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The relative velocity between baryons and dark matter in the early Universe can suppress the formation of small-scale baryonic structure and leave an imprint on the baryon acoustic oscillation (BAO) scale at low redshifts after reionization. This "streaming velocity" affects the post-reionization gas distribution by directly reducing the abundance of pre-existing mini-halos ($\lesssim 10^7 M_{\bigodot}$) that could be destroyed by reionization and indirectly modulating reionization history via photoionization within these mini-halos. In this work, we investigate the effect of streaming velocity on the BAO feature in HI 21 cm intensity mapping after reionization, with a focus on redshifts $3.5\lesssim z\lesssim5.5$. We build a spatially modulated halo model that includes the dependence of the filtering mass on the local reionization redshift and thermal history of the intergalactic gas. In our fiducial model, we find isotropic streaming velocity bias coefficients $b_v$ ranging from $-0.0043$ at $z=3.5$ to $-0.0273$ at $z=5.5$, which indicates that the BAO scale is stretched (i.e., the peaks shift to lower $k$). In particular, streaming velocity shifts the transverse BAO scale between 0.121% ($z=3.5$) and 0.35% ($z=5.5$) and shifts the radial BAO scale between 0.167% ($z=3.5$) and 0.505% ($z=5.5$). These shifts exceed the projected error bars from the more ambitious proposed hemispherical-scale surveys in HI (0.13% at $1σ$ per $Δz = 0.5$ bin).
description: 12 pages, 5 figures, accepted for publication in MNRAS
Iridoid glycosides and polyphenolic compounds from Teucrium chamaedrys L.
Creators: name: Frezza, Claudio
name: Venditti, Alessandro
name: Matrone, Giorgia
name: Serafini, Ilaria
name: Foddai, Sebastiano
name: Armandodoriano Bianco
name: Serafini, Mauro
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified

description: In this work, the phytochemical analysis of Teucrium chamaedrys L. collected in Italy was reported. Eight compounds were isolated and identified by means of classical column chromatography and spectroscopic techniques, such as NMR and MS. In detail, these compounds were: verbascoside (1), forsythoside b (2), samioside (3), alyssonoside (4), harpagide (5), 8-O-acetyl-harpagide (6), cirsiliol (7) and β-arbutin (8). The presence of these compounds, in particular iridoids and phenyl-ethanoid glycosides, has a chemotaxonomic relevance and results to be in perfect accordance with the current botanical classification of the species. In addition, it provides a phytochemical rationale for the use of this particular plant in the ethno-pharmacological field. Conversely, it is worth of mention the absence of potentially toxic components, unlike to what observed in other species of the genus which can no longer be used for ethno-medicinal purposes.
Additional file 4 of Metagenomic analysis reveals the microbiome and resistome in migratory birds
Creators: name: Cao, Jian
name: Hu, Yongfei
name: Liu, Fei
name: Wang, Yanan
name: Bi, Yuhai
name: Lv, Na
name: Li, Jing
name: Zhu, Baoli
name: Gao, George F.
Publisher: name: figshare
Year: 2020
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 4: Figure S4. The functional annotation of predicted non-redundant gene catalog based on functional database. (a) KEGG annontation, and (b) eggNOG annotation.
Investigating Shift-Variance of Convolutional Neural Networks in Ultrasound Image Segmentation
Creators: name: Sharifzadeh, Mostafa
name: Benali, Habib
name: Rivaz, Hassan
Publisher: name: arXiv
Year: 2021
Subjects: subject: Image and Video Processing (eess.IV)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: While accuracy is an evident criterion for ultrasound image segmentation, output consistency across different tests is equally crucial for tracking changes in regions of interest in applications such as monitoring the patients' response to treatment, measuring the progression or regression of the disease, reaching a diagnosis, or treatment planning. Convolutional neural networks (CNNs) have attracted rapidly growing interest in automatic ultrasound image segmentation recently. However, CNNs are not shift-equivariant, meaning that if the input translates, e.g., in the lateral direction by one pixel, the output segmentation may drastically change. To the best of our knowledge, this problem has not been studied in ultrasound image segmentation or even more broadly in ultrasound images. Herein, we investigate and quantify the shift-variance problem of CNNs in this application and further evaluate the performance of a recently published technique, called BlurPooling, for addressing the problem. In addition, we propose the Pyramidal BlurPooling method that outperforms BlurPooling in both output consistency and segmentation accuracy. Finally, we demonstrate that data augmentation is not a replacement for the proposed method. Source code is available at https://git.io/pbpunet and http://code.sonography.ai.
Complementing cell taxonomies with a multicellular functional analysis of tissues
Creators: name: Flores, Ricardo Omar Ramirez
name: Schäfer, Philipp Sven Lars
name: Küchenhoff, Leonie
name: Saez-Rodriguez, Julio
Publisher: name: arXiv
Year: 2024
Subjects: subject: Tissues and Organs (q-bio.TO)
subject: Cell Behavior (q-bio.CB)
subject: FOS: Biological sciences

description: The application of single-cell molecular profiling coupled with spatial technologies has enabled charting cellular heterogeneity in reference tissues and in disease. This new wave of molecular data has highlighted the expected diversity of single-cell dynamics upon shared external queues and spatial organizations. However, little is known about the relationship between single cell heterogeneity and the emergence and maintenance of robust multicellular processes in developed tissues and its role in (patho)physiology. Here, we present emerging computational modeling strategies that use increasingly available large-scale cross-condition single cell and spatial datasets, to study multicellular organization in tissues and complement cell taxonomies. This perspective should enable us to better understand how cells within tissues collectively process information and adapt synchronized responses in disease contexts and to bridge the gap between structural changes and functions in tissues.
description: 36 pages, 4 figures
Emergent Cosmology from Matrix Theory
Creators: name: Brahma, Suddhasattwa
name: Brandenberger, Robert
name: Laliberte, Samuel
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Matrix theory is a proposed non-perturbative definition of superstring theory in which space is emergent. We begin a study of cosmology in the context of matrix theory. Specifically, we show that matrix theory can lead to an emergent non-singular cosmology which, at late times, can be described by an expanding phase of Standard Big Bang cosmology. The horizon problem of Standard Big Bang cosmology is automatically solved. We show that thermal fluctuations in the emergent phase source an approximately scale-invariant spectrum of cosmological perturbations and a scale-invariant spectrum of gravitational waves. Hence, it appears that matrix theory can lead to a successful scenario for the origin of perturbations responsible for the currently observed structure in the universe while providing a consistent UV-complete description.
description: 12 pages; comments welcome
Displaced Higgs production in Type-III Seesaw at the LHC/FCC, MATHUSLA and Muon collider
Creators: name: Sen, Chandrima
name: Bandyopadhyay, Priyotosh
name: Dutta, Saunak
name: KT, Aleesha
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this article, we explore the possibility of displaced Higgs production from the decays of the heavy fermions in the Type-III seesaw extension of the Standard Model at the LHC/FCC and the muon collider. The displaced heavy fermions and the Higgs boson can be traced back by measuring the displaced charged tracks of the charged leptons along with the $b$-jets. A very small Yukawa coupling can lead to two successive displaced decays which makes the phenomenology even more interesting. The prospects of the transverse and longitudinal displaced decay lengths are extensively studied in the context of the boost at the LHC/FCC. Due to the parton distribution function, the longitudinal boosts leads to larger displacement compared to the transverse one, which can reach MATHUSLA and beyond. The longitudinal measurements are indeed possible by the visible part of the finalstate, which captures the complete information about the longitudinal momenta. The comparative studies are made at the LHC/FCC with the centre of mass energies of 14, 27 and 100 TeV, respectively. A futuristic study of the muon collider where the collision happen in the centre of mass frame is analysed for centre of mass energies of 3.5, 14 and 30 TeV. Contrary to LHC/FCC, here the transverse momentum diverges, however, the maximum reach in both the direction are identical due to the constant total momentum in each collision. The reach of the Yukawa couplings and fermion masses are appraised for both the colliders. FCC at 100 TeV can probe a mass of 4.25 TeV and a lowest Yukawa coupling of $\mathcal{O}(5 \times 10^{-11})$.
description: 39 pages, 29 figures and 17 tables, figures and text are updated
SMC-Last Extracted Photometry
Creators: name: Kuchar, T. A.
name: Sloan, G. C.
name: Mizuno, D. R.
name: Kraemer, Kathleen E.
name: Boyer, M. L.
name: Groenewegen, Martin A. T.
name: Jones, O. C.
name: Kemper, F.
name: McDonald, Iain
name: Oliveira, Joana M.
name: Sewiło, Marta
name: Srinivasan, Sundar
name: van Loon, Jacco Th.
name: Zijlstra, Albert
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present point-source photometry from the Spitzer Space Telescope's final survey of the Small Magellanic Cloud (SMC). We mapped 30 square degrees in two epochs in 2017, with the second extending to early 2018 at 3.6 and 4.5 microns using the Infrared Array Camera. This survey duplicates the footprint from the SAGE-SMC program in 2008. Together, these surveys cover a nearly 10 yr temporal baseline in the SMC. We performed aperture photometry on the mosaicked maps produced from the new data. We did not use any prior catalogs as inputs for the extractor in order to be sensitive to any moving objects (e.g., foreground brown dwarfs) and other transient phenomena (e.g., cataclysmic variables or FU Ori-type eruptions). We produced a point-source catalog with high-confidence sources for each epoch as well as combined-epoch catalog. For each epoch and the combined-epoch data, we also produced a more complete archive with lower-confidence sources. All of these data products will be available to the community at the Infrared Science Archive.
description: 16 pages, 11 figures, 6 tables
Weyl's laws and Connes' integration formulas for matrix-valued $L\log L$-Orlicz potentials
Creators: name: Ponge, Raphael
Publisher: name: arXiv
Year: 2021
Subjects: subject: Operator Algebras (math.OA)
subject: Spectral Theory (math.SP)
subject: FOS: Mathematics

description: Thanks to the Birman-Schwinger principle, Weyl's laws for Birman-Schwinger operators yields semiclassical Weyl's laws for the corresponding Schrödinger operators. In a recent preprint Rozenblum established quite general Weyl's laws for Birman-Schwinger operators associated with pseudodifferential operators of critical order and potentials that are product of $L\log L$-Orlicz functions and Alfhors-regular measures supported on a submanifold. In this paper, for matrix-valued $L\log L$-Orlicz potentials supported on the whole manifold, Rozenblum's results are direct consequences of the Cwikel-type estimates on tori recently established by Sukochev-Zanin. As applications we obtain CLR-type inequalities and semiclassical Weyl's laws for critical Schrödinger operators associated with matrix-valued$L\log L$-Orlicz potentials. Finally, we explain how the Weyl's laws of this paper imply a strong version of Connes' integration formula for matrix-valued $L\log L$-Orlicz potentials.
description: 23 pages. arXiv admin note: text overlap with arXiv:2107.01242
Local Financial Development and Household Welfare in Vietnam: Evidence from a Panel Survey
Creators: name: Tran, Viet T.
name: Yabibal M. Walle
name: Herwartz, Helmut
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: We examine the impact of local financial development on household welfare in Vietnam. We employ household-level panel data for the periods 2007, 2008, 2010 and 2013 covering three provinces and measure local financial development at the district, sub-district and village levels. To account for potential endogeneity that could emanate from the fact that local economic development could spur local financial development, we employ a recently suggested method of identification through heteroscedasticity. Our results show that local financial development has a significantly positive effect on household annual income, consumption and consumption smoothing.
Incidence and survival of oropharyngeal cancer in Denmark: a nation-wide, population-based study from 1980 to 2014
Creators: name: Jensen, Jakob Schmidt
name: Jensen, David Hebbelstrup
name: Grønhøj, Christian
name: Karnov, Kirstine Kim Schmidt
name: Nørregaard, Cecilie
name: Agander, Tina Klitmøller
name: Specht, Lena
name: Buchwald, Christian Von
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy

description: Background: Oropharyngeal carcinomas (OPCs) constitute a significant and increasing proportion of head and neck carcinomas and are an important global cause of morbidity and mortality. The purpose of this study was to determine trends in incidence and survival in OPC in the Danish population from 1980 to 2014. Methods: This study included all patients registered in the nationwide Danish Cancer Registry over the period 1980–2014. The age-adjusted incidence rates (AAIR) per 100,000, annual percentage change (APC) and average annual percent change (AAPC) were evaluated. Five-year relative survival (RS) was calculated with Cox regression analyses in relation to gender, anatomical location and histology. Results: A total of 6555 patients (69% male) were included, with a median age at diagnosis of 60 years. The AAIR of patients with OPC increased from 0.815 per 100,000 in 1980 to 4.51 per 100,000 in 2014 with an AAPC of 5.3. The 5-year RS increased significantly from 33.1% over the period 1980–1984 to 58.5% (25.4% points) over the period 2010–2014. With no significant difference stratified for gender. Tumors located at the palatine tonsils (n = 3333) and salivary gland OPC (n = 90) had significantly better survival compared with other sub-locations and histology subtypes. In the APC model the birth cohort effect rate ratio increased until 1925 and then decreased until 1935 from which point it increased in the last cohorts. Conclusions: In this population-based study, we observed a significant increase in the incidence of OPCs and in the RS for OPC. We also identified a profound birth cohort effect on the incidence.
Improving activity of anticancer oxalipalladium analog by the modification of oxalate group with isopentylglycine
Creators: name: Rasanani, Sara Hadian
name: Mahboube Eslami Moghadam
name: Esmaiela Soleimani
name: Adeleh Divsalar
name: Aliakbar Tarlani
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: In this article, we describe the influence of structure on biological behavior of amino acid-Pd complex and compare it with oxalipalladium. A new water-soluble oxalipalladium analog with formula of [Pd(DACH)(isopentylgly)](NO3), where DACH is 1R,2R-diaminocyclohexane, has been synthesized and characterized by elemental analysis, conductivity measurements, IR, UV–Vis, and 1H NMR spectroscopies. The interactions of oxalipalladium and its amino acid derivative with highly polymerized calf-thymus DNA have been extensively studied by spectroscopic methods. The high binding constants of oxalipalladium (0.38 × 104 M−1) and new amino acid-Pd complex (0.65 × 104 M−1) were determined using absorption measurements. Also circular dichroism (CD) studies show that Pd complex causes more disturbances on DNA structure rather than oxalipalladium. The experimental results proposed that [Pd(DACH)(isopentylgly)](NO3) is bound to DNA by groove-binding mode as well as partially covalent interaction, while oxalate analog binds covalently to DNA after hydrolysis. Interaction of the two metal derivative complexes was studied by molecular docking simulation. The results showed that amino acid-Pd complex has higher negative docking energy and higher tendency for interaction with DNA, and exert more structural change on DNA. Finally, the anticancer and growth inhibitory activities of synthesized complexes were investigated against human colon cancer cell line of HCT116 after 24 h incubation time using MTT assay. Results show that the complex [Pd(DACH)(isopentylgly)](NO3) showed enhanced anticancer and growth inhibitory activities against human colon can cell line HCT116.
Residual cut-off dependence and power counting: the deuteron as a case study
Creators: name: Odell, Daniel
name: Valderrama, Manuel Pavon
name: Platter, Lucas
Publisher: name: arXiv
Year: 2021
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Effective field theories (EFTs) require regularization and renormalization to gain predictive power. While regularization is inconsequential from the point of view of the observable predictions of EFT -- in a renormalized theory we expect predictions to be regulator-independent once the cutoff is removed -- the particular details of regulator dependence might provide interesting insights into the inner workings of an EFT. In fact, the analysis of regulator dependence has been frequently suggested as a tool to study the ordering scheme or power counting of EFTs. We show here that the choice of the regulator might impact the power law properties of the residual cutoff dependence. If this conclusion were to be confirmed, it would have consequences on the validity of this method as a tool to analyze power counting.
Theoretical investigation on molecular structure of a new mononuclear copper(II) thiocyanato complex with tridentate Schiff base ligand
Creators: name: Santarupa Thakurta
name: Butcher, Ray J.
name: Frontera, Antonio
name: Samiran Mitra
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer

description: An asymmetrical Schiff base ligand, 4-bromo-2-(2-pyridylmethyliminomethyl)phenol (HL), and its copper(II) complex, [Cu(L)SCN] (1), have been synthesized. Complex 1 is experimentally characterized by elemental analysis, FT-IR and UV–vis spectroscopic techniques, and cyclic voltammetry. The structure of the complex has been established by single-crystal X-ray diffraction studies, which reveal a square planar geometry of the central copper(II) ion in 1. The neighboring molecules of the complex connect each other by π–π stacking interactions with centroid-to-centroid ring distance 3.653 Å. The ligand can display two possible tautomeric forms; therefore, 1 can have an alternate molecular structure. DFT calculations have been employed to investigate the structure and relative stabilities of the suggested tautomeric forms of the ligand and its corresponding copper(II) complex.
Hot Extended Galaxy Halos Around Local L* Galaxies From Sunyaev-Zeldovich Measurements
Creators: name: Bregman, Joel N.
name: Hodges-Kluck, Edmund
name: Qu, Zhijie
name: Pratt, Cameron
name: Li, Jiang-Tao
name: Yun, Yansong
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Most of the baryons in L* galaxies are unaccounted for and are predicted to lie in hot gaseous halos (T ~ 3E6 K) that may extend beyond R200. A hot gaseous halo will produce a thermal Sunyaev-Zeldovich signal that is proportional to the product of the gas mass and the mass-weighted temperature. To best detect this signal, we used a Needlet Independent Linear Combination all-sky Planck map that we produced from the most recent Planck data release, also incorporating WMAP data. The sample is 12 L* spiral galaxies with distances of 3-10 Mpc, which are spatially resolved so that contamination from the optical galaxy can be excluded. One galaxy, NGC 891, has a particularly strong SZ signal, and when excluding it, the stack of 11 galaxies is detected at about 4sigma (declining with radius) and is extended to at least 250 kpc (~R_{200}) at > 99% confidence. The gas mass within a spherical volume to a radius of 250 kpc is 9.8 +/- 2.8 E10 Msun, for Tavg = 3E6 K. This is about 30% of the cosmic baryon content of the average galaxy (3.1E11 Msun), and about equal to the mass of stars, disk gas, and warm halo gas. The remaining missing baryons (~ 1.4E11 Msun, 40-50% of the total baryon content) are likely to be hot and extend to the 400-500 kpc volume, if not beyond. The result is higher than predictions, but within the uncertainties.
description: 25 pages, 11 figures, accepted by ApJ (30 Jan. 2022)
Heralded-Multiplexed High-Efficiency Cascaded Source of Dual-Rail Polarization-Entangled Photon Pairs using Spontaneous Parametric Down Conversion
Creators: name: Dhara, Prajit
name: Johnson, Spencer J.
name: Gagatsos, Christos N.
name: Kwiat, Paul G.
name: Guha, Saikat
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Deterministic sources of high-fidelity entangled qubit pairs encoded in the dual-rail photonic basis, i.e., presence of a single photon in one of two orthogonal modes, are a key enabling technology of many applications of quantum information processing, including high-rate high-fidelity quantum communications over long distances. The most popular and mature sources of such photonic entanglement, e.g., those that leverage spontaneous parametric down-conversion (SPDC) or spontaneous four-wave mixing (sFWM), generate an entangled (so-called, continuous-variable) quantum state that contains contributions from high-order photon terms that lie outside the span of the dual-rail basis, which is detrimental to most applications. One often uses low pump power to mitigate the effects of those high-order terms. However that reduces the pair generation rate, and the source becomes inherently probabilistic. We investigate a cascaded source that performs a linear-optical entanglement swap between two SPDC sources, to generate a heralded photonic entangled state that has a higher fidelity (to the ideal Bell state) compared to a free-running SPDC source. Further, with the Bell swap providing a heralding trigger, we show how to build a multiplexed source, which despite reasonable switching losses and detector loss and noise, yields a Fidelity versus Success Probability trade-off of a high-efficiency source of high-fidelity dual-rail photonic entanglement. We find however that there is a threshold of $1.5$ dB of loss per switch, beyond which multiplexing hurts the Fidelity versus Success Probability trade-off.
description: 24 pages, 32 figures, 7 appendices. Comments and reviews are welcome!
Stability of suspended monolayer graphene membranes in alkaline environment
Creators: name: A. Miranda
name: A. Lorke
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: We report on the structural, chemical and electrical compatibility of graphene in an alkaline environment, namely diluted KOH solutions as those used in standard nanofabrication methods. Electron microscopy and Raman spectroscopy indicate that graphene preserves its structural properties during the process. The electrical transport properties such as conductance and shape of the Dirac point, appear degraded after KOH treatment, but can be fully recovered by current annealing. Electron beam-induced etching can provide further nanofabrication subsequent to KOH processing. These results demonstrate that, with the due precautions, graphene-based structures can be integrated in standard fabrication processes involving KOH. IMPACT STATEMENT To be implemented in novel (nano) devices, graphene must be compatible with standard fabrication techniques. We show how graphene’s intrinsic properties can be restored after exposure to an alkaline environment.
Mucoadhesive tablets for the vaginal delivery of progesterone: in vitro evaluation and pharmacokinetics/pharmacodynamics in female rabbits
Creators: name: Hassan, Abeer S.
name: Ghareb M. Soliman
name: Ali, Marwa F.
name: El-Mahdy, Mona M.
name: El-Gindy, Gamal El-Din A.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified

description: Objective: To develop mucoadhesive tablets for the vaginal delivery of progesterone (P4) to overcome its low oral bioavailability resulting from drug hydrophobicity and extensive hepatic metabolism. Methods: The tablets were prepared using mixtures of P4/Pluronic® F-127 solid dispersion and different mucoadhesive polymers. The tablets physical properties, swelling index, mucoadhesion and drug release kinetics were evaluated. P4 pharmacokinetic and pharmacodynamic properties were evaluated in female rabbits and compared with vaginal micronized P4 tablets and intramuscular (IM) P4 injection, respectively. Results: The tablets had satisfactory physical properties and their swelling, in vitro mucoadhesion force and ex vivo mucoadhesion time were dependent on tablet composition. Highest swelling index and mucoadhesion time were detected for tablets containing 20% chitosan-10% alginate mixture. Most tablets exhibited burst release (∼25%) during the first 2 h but sustained the drug release for ∼48 h. In vivo study showed that chitosan-alginate mucoadhesive tablets had ∼2-fold higher P4 mean residence time (MRT) in the blood and 5-fold higher bioavailability compared with oral P4. Further, same tablets showed 2-fold higher myometrium thickness in rabbit uterus compared with IM P4 injection. Conclusion: These results confirm the potential of these mucoadhesive vaginal tablets to enhance P4 efficacy and avoid the side effects associated with IM injection.
Improving activity of anticancer oxalipalladium analog by the modification of oxalate group with isopentyl glycine
Creators: name: Rasanani, Sara Hadian
name: Mahboube Eslami Moghadam
name: Esmaeil Soleimani
name: Adeleh Divsalar
name: Tarlani, Ali Akbar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: In this paper, we describe the influence of structure on biological behavior of amino acid-Pd complex and compare it with oxalipalladium. A new water-soluble oxalipalladium analog with formula of [Pd(DACH)(isopentylgly)](NO3), where DACH is 1R,2R-diaminocyclohexane, has been synthesized and characterized by elemental analysis, conductivity measurements, IR, UV-Vis and 1HNMR spectroscopies. The interactions of oxalipalladium and its aminoacid derivative with highly-polymerized calf-thymus DNA have been extensively studied by spectroscopic methods. The high binding constants of oxalipalladium (0.38×104 M−1) and new amino acid-Pd complex (0.65×104 M−1) were determined using absorption measurements.Also circular dichroism (CD) studies show that Pd complex causes more disturbances on DNA structure rather than oxalipalladium. The experimental results proposed that [Pd(DACH)(isopentylgly)](NO3)is bound to DNA by groove-binding mode as well as partially covalent interaction, while oxalate analog binds covalently to DNA after hydrolysis. Interaction of the two metal derivative complexes was studied by molecular docking simulation. The results showed that amino acid-Pd complex has higher negative docking energy and higher tendency for interaction with DNA, and exert more structural change on DNA. Finally, the anticancer and growth inhibitory activities of synthesized complexes were investigated against human colon cancer cell line of HCT116 after 24 hours incubation time using MTT assay. Results show that the complex [Pd(DACH)(isopentylgly)](NO3) showed enhanced anticancer and growth inhibitory activities against human colon can cell line HCT116.
Additional file 9 of Sirtuin 5 aggravates microglia-induced neuroinflammation following ischaemic stroke by modulating the desuccinylation of Annexin-A1
Creators: name: Xia, Qian
name: Gao, Shuai
name: Han, Tangrui
name: Mao, Meng
name: Zhan, Gaofeng
name: Wang, Yonghong
name: Li, Xing
Publisher: name: figshare
Year: 2023
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Additional file 9: Full gels of the western blot images.
Additional file 1 of Identification and validation of stromal-tumor microenvironment-based subtypes tightly associated with PD-1/PD-L1 immunotherapy and outcomes in patients with gastric cancer
Creators: name: Ren, Qianqian
name: Zhu, Peng
name: Zhang, Hui
name: Ye, Tianhe
name: Liu, Dehan
name: Gong, Zhao
name: Xia, Xiangwen
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Table S1. Association between stromal score expression and the clinical parameters in the GEO cohort.
Supplementary tables and figures for "Contrasting ecological roles of non-native ungulates in a novel ecosystem."
Creators: name: Gawel, Ann Marie
name: Haldre S. Rogers
name: Miller, Ross H.
name: Kerr, Alexander M.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences

description: Compiled supplementary information for "Contrasting ecological roles of non-native ungulates in a novel ecosystem." File includes a map of field study sites in Guam, descriptive information justifying selection of paired seedling plot sites, and information on scat counts and vegetation transects accounting for points that appeared to drive trends. Analyses were rerun without the points in question, and general trends were not significantly different from what was reported in the main manuscript.
One year of the OpenCitations Corpus - Releasing RDF-based scholarly citation data into the Public Domain
Creators: name: Peroni, Silvio
Publisher: name: figshare
Year: 2017
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Reference lists from academic articles are core elements of scholarly communication that permit the attribution of credit and integrate our independent research endeavours. Hitherto, however, they have not been freely available in an appropriate machine-readable format such as RDF and in aggregate for use by scholars. To address this issue, one year ago we started ingesting citation data from the Open Access literature into the OpenCitations Corpus (OCC), creating an RDF dataset of scholarly citation data that is open to all. In this paper we introduce the OCC and we discuss its outcomes and uses after the first year of life.
Radio and Far-IR Emission Associated with a Massive Star-forming Galaxy Candidate at z$\simeq$6.8: A Radio-Loud AGN in the Reionization Era?
Creators: name: Endsley, Ryan
name: Stark, Daniel P.
name: Fan, Xiaohui
name: Smit, Renske
name: Wang, Feige
name: Yang, Jinyi
name: Hainline, Kevin
name: Lyu, Jianwei
name: Bouwens, Rychard
name: Schouws, Sander
Publisher: name: arXiv
Year: 2021
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report the identification of radio (0.144-3 GHz), mid-IR, far-IR, and sub-mm (24-850$μ$m) emission at the position of one of 41 UV-bright (M$_\mathrm{UV}^{}\lesssim-21.25$) $z\simeq6.6-6.9$ Lyman-break galaxy candidates in the 1.5 deg$^2$ COSMOS field. This source, COS-87259, exhibits a sharp flux discontinuity (factor $>$3) between two narrow/intermediate bands at 9450 and 9700 Angstroms and is undetected in all nine bands blueward of 9600 Angstroms, as expected from a Lyman-alpha break at $z\simeq6.8$. The full multi-wavelength (X-ray through radio) data of COS-87529 can be self-consistently explained by a very massive (M$_{\ast}=10^{10.8}$ M$_{\odot}$) and extremely red (rest-UV slope $β=-0.59$) $z\simeq6.8$ galaxy with hyperluminous infrared emission (L$_{\mathrm{IR}}=10^{13.6}$ L$_{\odot}$) powered by both an intense burst of highly-obscured star formation (SFR$\approx$1800 M$_{\odot}$ yr$^{-1}$) and an obscured ($τ_{\mathrm{9.7μm}}=7.7\pm2.5$) radio-loud (L$_{\mathrm{1.4\ GHz}}\approx10^{25.4}$ W Hz$^{-1}$) AGN. The radio emission is compact (1.04$\pm$0.12 arcsec) and exhibits an ultra-steep spectrum between 1.32-3 GHz ($α=-1.57^{+0.22}_{-0.21}$) that flattens at lower frequencies ($α=-0.86^{+0.22}_{-0.16}$ between 0.144-1.32 GHz), consistent with known $z>4$ radio galaxies. We also demonstrate that COS-87259 may reside in a significant (11$\times$) galaxy overdensity at $z\simeq6.6-6.9$, as common for systems hosting radio-loud AGN. Nonetheless, a spectroscopic redshift will ultimately be required to establish the true nature of COS-87259 as we cannot yet completely rule out low-redshift solutions. If confirmed to lie at $z\simeq6.8$, the properties of COS-87259 would be consistent with a picture wherein AGN and highly-obscured star formation activity are fairly common among very massive (M$_{\ast}>10^{10}$ M$_{\odot}$) reionization-era galaxies.
description: 14 pages, 6 figures. Accepted in MNRAS with minor revisions. This accepted version considers very recent data from LOFAR and MeerKAT which improve our analyses on the radio slope and luminosity
A Closer Look at Implementations
Creators: name: Selm, Mariette Van
name: Scherer, Dave
name: Hardeman, Megan
name: Team Figshare
Publisher: name: figshare
Year: 2018
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Mariëtte van Selm, Coordinator of Research Data Support at the University of Amsterdam, and Dave Scherer, Scholarly Communications and Research Curation Consultant at Carnegie Mellon University, give their take on the figshare implementation at their respective universities.
Asymptotic estimations of a perturbed symmetric eigenproblem
Creators: name: Gissler, Armand
name: Auger, Anne
name: Hansen, Nikolaus
Publisher: name: arXiv
Year: 2024
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 15A42, 15B57

description: We study ill-conditioned positive definite matrices that are disturbed by the sum of $m$ rank-one matrices of a specific form. We provide estimates for the eigenvalues and eigenvectors. When the condition number of the initial matrix tends to infinity, we bound the values of the coordinates of the eigenvectors of the perturbed matrix. Equivalently, in the coordinate system where the initial matrix is diagonal, we bound the rate of convergence of coordinates that tend to zero.
On the Cosmic Number
Creators: name: Smith, John
Publisher: name: figshare
Year: 2017
Subjects: subject: 20203 Particle Physics
subject: FOS: Physical sciences
subject: Quantum Mechanics
subject: 10101 Algebra and Number Theory
subject: FOS: Mathematics

description: Richard Feynman said in the 80s: "There is a most profound and beautiful question associated with the observed coupling constant, e - the amplitude for a real electron to emit or absorb a real photon. It is a simple number that has been experimentally determined to be close to 0.08542455. (My physicist friends won't recognize this number, because they like to remember it as the inverse of its square: about 137.03597 with about an uncertainty of about 2 in the last decimal place. It has been a mystery ever since it was discovered more than fifty years ago, and all good theoretical physicists put this number up on their wall and worry about it.) Immediately you would like to know where this number for a coupling comes from: is it related to pi or perhaps to the base of natural logarithms? Nobody knows. It's one of the greatest damn mysteries of physics: a magic number that comes to us with no understanding by man. You might say the "hand of G-d" wrote that number, and "we don't know how He pushed his pencil." We know what kind of a dance to do experimentally to measure this number very accurately, but we don't know what kind of dance to do on the computer to make this number come out, without putting it in secretly!" In fact, Armand Wyler had pointed out in 1969 that (9/16\[Pi]^3)(\[Pi]/5!)^1/4 is close to 1/137, but failed to convince anyone that his explanation of the connection -that the number is a property of a 7-dimensional space-time- was viable. In this note, it is suggested that the reason for the closeness of another expression to 1/137 is, not a numerical curiosity, but -ironically- an indicator of the truth of a multi-dimensional physical theory.
Additional file 4 of Identification and validation of stromal-tumor microenvironment-based subtypes tightly associated with PD-1/PD-L1 immunotherapy and outcomes in patients with gastric cancer
Creators: name: Ren, Qianqian
name: Zhu, Peng
name: Zhang, Hui
name: Ye, Tianhe
name: Liu, Dehan
name: Gong, Zhao
name: Xia, Xiangwen
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer

description: Additional file 4: Table S3. Go terms of DEGs.
A Closer Look at Implementations
Creators: name: Selm, Mariette Van
name: Scherer, Dave
name: Hardeman, Megan
Publisher: name: figshare
Year: 2017
Subjects: subject: Library and Information Studies
subject: FOS: Media and communications

description: Mariëtte van Selm, Coordinator of Research Data Support at the University of Amsterdam, and Dave Scherer, Scholarly Communications and Research Curation Consultant at Carnegie Mellon University, give their take on the figshare implementation at their respective universities.
Tailoring Stimuli-responsive Ultra-Porous Nanocomposite for Release of Gas on Demand
Creators: name: MUHAMMAD MUNIR SADIQ
Publisher: name: Monash University
Year: 2017
Subjects: subject: 30108 Separation Science
subject: FOS: Chemical sciences
subject: 90404 Membrane and Separation Technologies
subject: FOS: Chemical engineering

description: The need to protect and care for the environment has led to the development of interesting and unique materials capable of reducing the level of carbon dioxide emissions from industries and coal mines. One class of such materials, that act like a sponge when exposed to carbon dioxide and methane are known as metal organic frameworks (MOFs). A teaspoon of these MOFs is capable of mopping a football field volume equivalent of CO2. Despite this huge capacity, it is very difficult to remove the adsorbed gas from these materials. This thesis investigated the use of heat generating magnetic nanoparticles in removing the adsorbed gas effectively and efficiently.
title: 02_0232
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Unitary Kinematic Mixing of Electro-Weak Bosons
Creators: name: Lindesay, James
Publisher: name: arXiv
Year: 2021
Subjects: subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: In the standard model, electro-weak bosons are developed as gauge-fields initially satisfying an SU(2) $\times$ U(1) local symmetry mediating interactions with a multi-component field. This symmetry gets broken when the component of the field associated with the (scalar) Higgs boson acquires a non-vanishing expectation value, generating masses for weak vector bosons (W$^+$,W$^-$,Z) as well as a massless photon (A) which couples to electric charge. Beyond an expression relating the masses of the W and Z bosons, there are few predictions concerning further relationships involving the Higgs mass or mixing angle. In this paper, kinematic relationships between unitarily mixed momentum-space spinors (supplemental to standard electro-weak modeling) will be developed. These relationships expressed in terms of kinematic invariants are shown to be consistent with current measured results.
description: 10 pages, 1 figure
Topology optimization for acoustic structures considering viscous and thermal boundary layers using a sequential linearized Navier-Stokes model
Creators: name: Noguchi, Yuki
name: Yamada, Takayuki
Publisher: name: arXiv
Year: 2021
Subjects: subject: Computational Engineering, Finance, and Science (cs.CE)
subject: FOS: Computer and information sciences

description: This study proposes a level set-based topology optimization method for designing acoustic structures with viscous and thermal boundary layers in perspective. Acoustic waves propagating in a narrow channel are damped by viscous and thermal boundary layers. To estimate these viscothermal effects, we first introduce a sequential linearized Navier-Stokes model based on three weakly coupled Helmholtz equations for viscous, thermal, and acoustic pressure fields. Then, the optimization problem is formulated, where a sound-absorbing structure comprising air and an isothermal rigid medium is targeted, and its sound absorption coefficient is set as an objective function. The adjoint variable method and the concept of the topological derivative are used to approximately obtain design sensitivity. A level set-based topology optimization method is used to solve the optimization problem. Two-dimensional numerical examples are provided to support the validity of the proposed method. Moreover, the mechanisms that lead to the high absorption coefficient of the optimized design are discussed.