cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Macromotettixoides jiuwanshanensis Zheng, Wei & Jiang 2005
Creators: name: Li, Yuemei
name: Leng, Shixiong
name: He, Jiasong
name: Deng, Weian
name: Guan, Delong
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tetrigidae
Macromotettixoides
Macromotettixoides jiuwanshanensis

description: Macromotettixoides jiuwanshanensis Zheng, Wei & Jiang, 2005
Figs 15, 16
Macromotettixoides jiuwanshanensis Zheng, Wei & Jiang, 2005: 366 [description] (holotype – ♀, China: Guangxi Prov., Luocheng (jiuwanshan), in IZSNU, examined). Zheng et al. 2005 b: 176; Zheng et al. 2006: 604; Deng et al. 2007: 160; Zheng and Shi 2009: 572; Deng 2011: 544; Zheng 2013 a: 242; Deng et al. 2014: 548; Deng et al. 2015: 1 65; Deng 2016: 156; Zha et al. 2017: 16; Han et al. 2020: 563; Li et al. 2020 a: 110; Fan et al. 2023: 128.
Hyboella badagongshanensis Zheng, 2013 b: 11 (holotype – ♀, China: Hunan Prov., Sangzhi (Badagongshan), in IZSNU, examined); Deng 2016: 150; syn. nov.
Macromotettixoides badagongshanensis (Zheng, 2013 b): Zha, Yu, Boonmee, Eungwanichayapant, Wen, 2017: 23; Han et al. 2020: 564; Li et al. 2020 a: 112; Fan et al. 2023: 129; syn. nov.
Macromotettixoides wuyishana Zheng, 2013: 242 [description] (holotype – ♀, China: Fujian Prov., Wuyishan, in IZSNU, examined); Deng 2016: 156; Zha et al. 2017: 15; Han et al. 2020: 563; Li et al. 2020 a: 1 11; Fan et al. 2023: 128; syn. nov.
Remarks.
Hyboella badagongshanensis was described by Zheng (2013 b) but was later transferred to the genus Macromotettixoides by Zha et al. (2017). We examined the type specimens of M. jiuwanshanensis, M. badagongshanensis, and M. wuyishana and found that the structures and coloration of the body are the same in these three taxa. Therefore, we consider M. badagongshanensis, and M. wuyishana as synonyms of M. jiuwanshanensis. These three taxa are conspecific and characterized by the width of the vertex between the eyes being 2.1–2.2 × the width of the compound eye; anterior margin of fastigium arched and surpassing anterior margin of eye; the anterior margin of pronotum is slightly obtuse protruding; and the lower carinae of fore and mid femora is straight.
description: Published as part of Li, Yuemei, Leng, Shixiong, He, Jiasong, Deng, Weian & Guan, Delong, 2025, Mitochondrial phylogenomics of pygmy grasshoppers (Orthoptera, Tetrigidae, Metrodorinae): descriptions of a new genus, two new species, and new synonyms from China, pp. 249-281 in ZooKeys 1236 on pages 249-281, DOI: 10.3897/zookeys.1236.145914
Effects of depressive symptoms and peripheral DAT methylation on neural reactivity to alcohol cues in alcoholism
Creators: name: Wiers, C. E.
name: Shumay, E.
name: Volkow, N. D.
name: Frieling, H.
name: Kotsiari, A.
name: Lindenmeyer, J.
name: Walter, H.
name: Bermpohl, F.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: In alcohol-dependent (AD) patients, alcohol cues induce strong activations in brain areas associated with alcohol craving and relapse, such as the nucleus accumbens (NAc) and amygdala. However, little is known about the influence of depressive symptoms, which are common in AD patients, on the brain’s reactivity to alcohol cues. The methylation state of the dopamine transporter gene (DAT) has been associated with alcohol dependence, craving and depression, but its influence on neural alcohol cue reactivity has not been tested. Here, we compared brain reactivity to alcohol cues in 38 AD patients and 17 healthy controls (HCs) using functional magnetic resonance imaging and assessed the influence of depressive symptoms and peripheral DAT methylation in these responses. We show that alcoholics with low Beck’s Depression Inventory scores (n=29) had higher cue-induced reactivity in NAc and amygdala than those with mild/moderate depression scores (n=9), though subjective perception of craving was higher in those with mild/moderate depression scores. We corroborated a higher DAT methylation in AD patients than HCs, and showed higher DAT methylation in AD patients with mild/moderate than low depression scores. Within the AD cohort, higher methylation predicted craving and, at trend level (P=0.095), relapse 1 year after abstinence. Finally, we show that amygdala cue reactivity correlated with craving and DAT methylation only in AD patients with low depression scores. These findings suggest that depressive symptoms and DAT methylation are associated with alcohol craving and associated brain processes in alcohol dependence, which may have important consequences for treatment. Moreover, peripheral DAT methylation may be a clinically relevant biomarker in AD patients.
Supplementary document for SOFISM: Super-resolution optical fluctuation image scanning microscopy - 4778489.pdf
Creators: name: Sroda, Aleksandra
name: Makowski, Adrian
name: Tenne, Ron
name: Rossman, Uri
name: Lubin, Gur
name: Oron, Dan
name: Lapkiewicz, Radek
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: This document provides supplementary information to the article "SOFISM: Super-resolution optical fluctuation image scanning microscopy". The document presents details of the experimental system, sample preparation, data analysis, and SOFISM theory.
Photoplethysmography and Deep Learning: Enhancing Hypertension Risk Stratification
Creators: name: Liang, Yongbo
name: Chen, Zhencheng
name: Ward, Rabab Kreidieh
name: Elgendi, Mohamed
Publisher: name: Multidisciplinary Digital Publishing Institute
Year: 2019

description: Blood pressure is a basic physiological parameter in the cardiovascular circulatory system. Long-term abnormal blood pressure will lead to various cardiovascular diseases, making the early detection and assessment of hypertension profoundly significant for the prevention and treatment of cardiovascular diseases. In this paper, we investigate whether or not deep learning can provide better results for hypertension risk stratification when compared to the classical signal processing and feature extraction methods. We tested a deep learning method for the classification and evaluation of hypertension using photoplethysmography (PPG) signals based on the continuous wavelet transform (using Morse) and pretrained convolutional neural network (using GoogLeNet). We collected 121 data recordings from the Multiparameter Intelligent Monitoring in Intensive Care (MIMIC) Database, each containing arterial blood pressure (ABP) and photoplethysmography (PPG) signals. The ABP signals were utilized to extract blood pressure category labels, and the PPG signals were used to train and test the model. According to the seventh report of the Joint National Committee, blood pressure levels are categorized as normotension (NT), prehypertension (PHT), and hypertension (HT). For the early diagnosis and assessment of HT, the timely detection of PHT and the accurate diagnosis of HT are significant. Therefore, three HT classification trials were set: NT vs. PHT, NT vs. HT, and (NT + PHT) vs. HT. The F-scores of these three classification trials were 80.52%, 92.55%, and 82.95%, respectively. The tested deep method achieved higher accuracy for hypertension risk stratification when compared to the classical signal processing and feature extraction method. Additionally, the method achieved comparable results to another approach that requires electrocardiogram and PPG signals.
Supplementary document for Towards label-free 3D segmentation of optical coherence tomography images of the optic nerve head using deep learning - 4778733.pdf
Creators: name: Devalla, Sripad Krishna
name: Pham, Tan Hung
name: Panda, Satish Kumar
name: Liang, Zhang
name: Subramanian, Giridhar
name: Swaminathan, Anirudh
name: Chin, Zhi Yun
name: Rajan, Mohan
name: Mohan, Sujatha
name: Krishnadas, Ramaswami
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
Vitamin D receptors, tissue growth and insulin dependent diabetes.
Creators: name: Stone, Lisa A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Chemistry, Biochemistry.

description: The studies described in this thesis evaluate the effect of insulin dependent diabetes on vitamin D receptors (VDR) and tissue growth in two models of insulin dependent diabetes: the streptozotocin-induced diabetic rat and the spontaneously diabetic BB rat. In both models, untreated diabetes was associated with decreased circulating 1,25-dihydroxycholecalciferol (1,25 DHCC), disturbed mineral homeostasis and up regulation of intestinal VDRs. The increase in unoccupied VDRs was associated with compensatory tissue growth in the intestine and hyperplasia. Low circulating 1,25 DHCC prevented amplification of the action of 1,25 DHCC despite up-regulation of intestinal VDRs, as evidenced by a reduction in calbindin D-9K in the diabetic intestine. The above parameters were normalized in STZ diabetic rats treated with exogenous insulin. There were no alterations in VDR numbers in kidneys or thymus of untreated diabetic animals, indicating that up-regulation of VDRs did not occur in all vitamin D target tissues. Unlike the intestine, compensatory growth in the kidney was not associated with hyperplasia, suggesting tissue specific changes in 1,25 DHCC metabolism during untreated diabetes which may be related to hyperplasia.
Identification and conceptualization of expert high performance gymnastic coaches' knowledge.
Creators: name: Côté, Jean.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Education, Physical.

description: An expert system approach (Buchanan et al., 1983) was used to identify and conceptualize the knowledge of 17 Canadian expert high performance gymnastic coaches. The selection of expert high performance coaches was based on multiple criteria. First, a minimum of 10 years of coaching experience was required. Second, each of the expert coaches required a performance outcome measure, and thus needed to have developed at least one international and two national level gymnasts. Finally, each expert coach had to be recognized by Canada's national coach as one of the best in Canada for developing elite gymnasts. By using a qualitative research method based on the traditions of cognitive anthropology (Spradley, 1979) and symbolic interactionism (Blumer, 1969; Glaser & Strauss, 1967), this study focused on the first two stages of the knowledge aquisition process for building an expert system: identification and conceptualization. The results of the identification stage indicated that the interview transcripts of coaches of males and females were divided into 595 and 560 meaningful episodes of information or "meaning units" (Tesch, 1990), respectively. The inductive analysis process allowed these meaning units to be regrouped into 134 properties, 28 categories, and 6 components. The components emerging from the analysis were the same for coaches of males and females and consisted of: (1) competition, (2) training, (3) organization, (4) coach's personal characteristics, (5) gymnast's personal characteristics and level of development, and (6) contextual factors. The categories and properties of coaches' knowledge varied slightly in number and by their nature for coaches of males and coaches of females. Attempts to explain differences in the categories of knowledge elicited by coaches of males and coaches of females were made in light of the evident age-related and gender specific task differences in men's and women's gymnastics. The results of the conceptualization stage indicated that the coaches' mental model of various situations was built through the assessment of three "peripheral components," consisting of their own personal characteristics, the gymnasts' personal characteristics and level of development, and some contextual factors. The mental model resulting from this assessment guided the coaches for their intervention in the "competition," "training," and "organization" components, defined as the "coaching process." The large arsenal of coaches' organized hierarchically through the difference properties, categories, and components allows expert coaches to rapidly assess situations that do not fit their mental model and, consequently make the appropriate changes. (Abstract shortened by UMI.)
Supplementary document for Towards label-free 3D segmentation of optical coherence tomography images of the optic nerve head using deep learning - 4778733.pdf
Creators: name: Devalla, Sripad Krishna
name: Pham, Tan Hung
name: Panda, Satish Kumar
name: Liang, Zhang
name: Subramanian, Giridhar
name: Swaminathan, Anirudh
name: Chin, Zhi Yun
name: Rajan, Mohan
name: Mohan, Sujatha
name: Krishnadas, Ramaswami
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Uncategorized

description: Supplement 1
Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9
Creators: name: Gundry, Michael C.
name: Brunetti, Lorenzo
name: Lin, Angelique
name: Mayle, Allison E.
name: Kitano, Ayumi
name: Wagner, Dimitrios
name: Hsu, Joanne I.
name: Hoegenauer, Kevin A.
name: Rooney, Cliona M.
name: Goodell, Margaret A.
name: Nakada, Daisuke
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Summary Our understanding of the mechanisms that regulate hematopoietic stem/progenitor cells (HSPCs) has been advanced by the ability to genetically manipulate mice; however, germline modification is time consuming and expensive. Here, we describe fast, efficient, and cost-effective methods to directly modify the genomes of mouse and human HSPCs using the CRISPR/Cas9 system. Using plasmid and virus-free delivery of guide RNAs alone into Cas9-expressing HSPCs or Cas9-guide RNA ribonucleoprotein (RNP) complexes into wild-type cells, we have achieved extremely efficient gene disruption in primary HSPCs from mouse (>60%) and human (∼75%). These techniques enabled rapid evaluation of the functional effects of gene loss of Eed, Suz12, and DNMT3A. We also achieved homology-directed repair in primary human HSPCs (>20%). These methods will significantly expand applications for CRISPR/Cas9 technologies for studying normal and malignant hematopoiesis.
An infrared spectroscopic study of adsorbed species on nickel and platinum.
Creators: name: Moran, Lyle Edwin.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1977
Subjects: subject: Chemistry, Analytical.

description: In this thesis, infrared spectroscopy has been used to study adsorbed species on silica-supported nickel and platinum catalysts. The chemisorption of the oxides of nitrogen (particularly nitric oxide) was studied initially, followed by a study of the chemisorption and oxidation of pyridine on bare and oxidized nickel and platinum. The results of these studies will be described below. Infrared spectral data have shown that nitric oxide chemisorbs on Ni/SiO 2 to form a single adsorbed species, which has been attributed to linear, neutral Ni-NO. On Pt/SiO2 two major surface species were produced and these have been assigned to linear, neutral Pt-NO and bent Pt-NO. In addition, the spectral data have indicated that, at high surface coverage, other nitrogen-oxygen containing species are formed one of which has been tentatively identified as PtONO2. The study of nitrogen dioxide chemisorption has demonstrated that nitrogen dioxide dissociates on both Ni/SiO2 and Pt/SiO2 to form adsorbed nitric oxide and oxygen. Isotopic substitution experiments have shown that carbon monoxide and nitric oxide react over Ni/SiO2 to form a surface nickel isocyanate species and the formation of this species is independent of the order of the addition of the reactants. However, on Pt/SiO2 a surface isocyanate species was generated only if the nitric oxide was preadsorbed at low surface coverage. In both studies, it has been concluded that very little M-NCO is produced (M = Ni or Pt). When hydrogen was added to chemisorbed nitric oxide on Pt/SiO2, two new surfaces species are formed and these have been identified as Pt-NH 3 and Pt2O2NH. In addition to the above results, this thesis also contains extensive reviews of the chemisorption of nitric oxide and nitrogen dioxide and of the formation of surface isocyanate species on the transition metals. Pyridine. Infrared spectral data have indicated that pyridine dissociatively chemisorbs on Pt/SiO2 to form a Pt-C sigma bond at the 'ortho' position and a coordinate bond with the N-atom such that the molecule lies perpendicular to the surface. On Ni/SiO2 a different strongly adsorbed species is formed which has been identified as a simple nitrogen-coordinated pyridine which also lies perpendicular to the surface, and, as proposed by others, the coordination of this species is promoted if the nickel surface is pretreated with either CO or O2. When oxygen is added to chemisorbed pyridine on Pt/SiO2 two new adsorbed species are formed and these have been assigned to a surface (N=0) containing species of the type, PtNOx (x = 2 or 3) or Pt2NO, and a cyclic C5 derivative of unknown structure. The same species were formed on oxidized Pt/SiO2, but, in addition, coordinated pyridine is formed.
Differential and coherent RAKE receivers for DS-CDMA in frequency-selective Rayleigh fading channels.
Creators: name: D'Amours, Claude.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1992
Subjects: subject: Engineering, Electronics and Electrical.

description: The performance of digital communications over frequency-selective Rayleigh fading channels can be quite poor, thus diminishing, the capacity of a DS-CDMA system. This thesis compares differential detection, multiple symbol differential detection and pilot symbol-aided coherent detection of a direct-sequence spread spectrum signal for this channel. Diversity reception is obtained through RAKE reception, and both equal gain and maximal gain diversity combining are considered. The improvement provided by some error correcting convolutional codes arid interleaving are also studied.
The Translatability of Emotiveness in Mahmoud Darwish's Poetry
Creators: name: Mahasneh, Anjad
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Literature, Middle Eastern.
subject: Language, General.

description: This study addresses the translatability of emotive expressions in the poetry of the distinguished Palestinian poet Mahmoud Darwish. The study gives translators and readers an example of how to look at emotiveness in the Arabic poetry by studying main sources of emotiveness like cultural expressions, figures of speech such as rhetorical questions and repetitions as well as expressions of direct emotiveness such as proper names. The ambition of this study is to enrich the literature on translation with new examples of emotiveness by pointing out the expected problem areas when translating emotive expressions. Furthermore, this study is significant since it attempts to answer the question of whether emotiveness constitutes a problem when translating from Arabic into English and whether the meaning and the musicality of poetry are translatable or not. The English translations are selected from: 1. Unfortunately, It Was Paradise translated and edited by Munir Akash and Carolyn Forche with Sinan Antoon and Amira El-Zein (2003) e 2. The Butterfly's Burden translated by Fady Joudah (2007). The original poems can be found in Darwish's most recent poetry collections included in the 2009 edition of The Complete Recent Works by Mahmoud Darwish, published in Beirut. The emotive expressions selected from the English collections and compared to the Arabic original are divided into three categories: the cultural expressions, the linguisticexpressions, and the political expressions. The study highlights different emotive devices used in the selection of poems, by carrying out an analysis of the English translation as well as the Arabic original text. The emotive expressions selected are carefully analyzed to show how the translation was able to render the emotive meaning expressed and intended by the poet in the text in its original form.
Linking Core Promoter Classes to Circadian Transcription
Creators: name: Westermark, Pål O.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Abstract Circadian rhythms in transcription are generated by rhythmic abundances and DNA binding activities of transcription factors. Propagation of rhythms to transcriptional initiation involves the core promoter, its chromatin state, and the basal transcription machinery. Here, I characterize core promoters and chromatin states of genes transcribed in a circadian manner in mouse liver and in Drosophila. It is shown that the core promoter is a critical determinant of circadian mRNA expression in both species. A distinct core promoter class, strong circadian promoters (SCPs), is identified in mouse liver but not Drosophila. SCPs are defined by specific core promoter features, and are shown to drive circadian transcriptional activities with both high averages and high amplitudes. Data analysis and mathematical modeling further provided evidence for rhythmic regulation of both polymerase II recruitment and pause release at SCPs. The analysis provides a comprehensive and systematic view of core promoters and their link to circadian mRNA expression in mouse and Drosophila, and thus reveals a crucial role for the core promoter in regulated, dynamic transcription. Author Summary Circadian rhythms switch gene expression on and off with a daily rhythm in most tissues in mammals and other animals. Typically, thousands of genes are affected, and the functions of these rhythms include preparing and adjusting various physiological functions in tissues to meet time-of-day dependent requirements optimally. The controllers of the rhythms are often transcription factors (proteins which regulate transcription), which are relatively well known. However, there is a layer between transcription factor action and transcriptional activity whose role in circadian transcription has not previously been characterized: the core promoter. The core promoter acts as a template for the assembly of the intricate machinery that governs initiation of transcription. There are different types of core promoters that are typically used for different types of genes. It is not known which types of core promoters are used for the rhythmically induced genes. Here, it is shown that there are specific characteristics of core promoters driving rhythmic transcription in mice and flies. Furthermore, it is shown that there is a class of strong circadian promoters in mice that drive strong rhythms with very intense average transcriptional rates. These results help understanding the regulatory systems governing circadian transcription, and ultimately, aid the understanding of many diseases resulting from disturbed circadian rhythms.
Distress and satisfaction with research participation: Impact on retention in longitudinal disaster research
Creators: name: Gibbs, Lisa
name: Molyneaux, Robyn
name: Whiteley, Sonia
name: Block, Karen
name: Harms, Louise
name: Bryant, Richard A.
name: Forbes, David
name: Gallagher, Colin
name: MacDougall, Colin
name: Ireton, Greg
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 441006
subject: Sociological methodology and research methods
classificationCode: 520207
subject: Social and affective neuroscience
classificationCode: 520501
subject: Community psychology
classificationCode: 520505
subject: Social psychology

description: Previous studies of the impact of post-trauma research participation indicate that while the research experience may be emotional, it can still be valued by participants. This paper describes participant experiences of the Australian post-bushfire research study–Beyond Bushfires. It examines the relationships between distress during research participation, probable mental health conditions, and satisfaction with the research experience over time. A range of strategies was incorporated into the study, including a distress and risk assessment and referral protocol, to minimise any risk of harm for people who had experienced the 2009 bushfires and their aftermath. Participants included 1056 respondents (Wave 1) interviewed via telephone and web-based survey between December 2011 through January 2013, and 736 (76.1%) of the participants were re-surveyed between July and November 2014 (Wave 2). Research impact was monitored through two questions about survey experience on each occasion. Reported distress at completing the survey was generally low, while overall satisfaction was relatively high. Participants’ reported satisfaction was not associated with their reported level of distress as a result of the survey; and reported participation distress at Wave 1 did not predict whether a respondent would return to complete the survey at Wave 2. Fire-related Posttraumatic stress symptoms were associated with increased satisfaction and likelihood to return at Wave 2. These findings suggest that for Beyond Bushfires survey respondents the perceived benefits outweighed the costs of participation over time.
DESIGN & AEROELASTIC ANALYSIS OF MULTISTABLE RADIALLY FOLDABLE THIN WING
Creators: name: Michalaros, Dimitrios
Publisher: name: Purdue University Graduate School
Year: 2025
Subjects: classificationCode: 400102
subject: Aerospace structures

description: In this thesis project, we investigate the design of a bioinspired radially foldable multistable wing stiffened with bistable pyramidal units, to enable an aerial-aquatic vehicle to switch from an aquatic to an aerial mode and back. In the process of redesigning this morphing wing to improve upon its performance, we invent new methods to more effectively stiffen and control the revolute joint DOFs of radially foldable structures (which is the broader origami inspired structure category of the wing) with new bistable units that draw inspiration from a binder clip spring. Finally, we improve upon the Binder Clip Inspired (BCI) unit design by creating a multistable BCI version with an intermediate stable state to allow for lift distribution control of the wing by introducing a new geometric feature to this stiffening element. This extra feature renders the new BCI version multistable, and adds a high-lift configuration for the multistable fan-like wing. In the future, these multistable units that create a passively stable high-lift flap device can be implemented instead of traditionally actuated flap mechanisms in any aircraft, with fixed or foldable wings.
DNA methylation profiling of acute chorioamnionitis-associated placentas and fetal membranes: insights into epigenetic variation in spontaneous preterm births
Creators: name: Konwar, Chaini
name: Price, E. M.
name: Wang, Li Qing
name: Wilson, Samantha L.
name: Terry, Jefferson
name: Robinson, Wendy P.
Publisher: name: BioMed Central
Year: 2018

description: Background: Placental inflammation, often presenting as acute chorioamnionitis (aCA), is commonly associated with preterm birth. Preterm birth can have both immediate and long-term adverse effects on the health of the baby. Developing biomarkers of inflammation in the placenta can help to understand its effects and potentially lead to new approaches for rapid prenatal diagnosis of aCA. We aimed to characterize epigenetic variation associated with aCA in placenta (chorionic villi) and fetal membranes (chorion and amnion) to better understand how aCA may impact processes that lead to preterm birth. This study lays the groundwork for development of novel biomarkers for aCA. Methods: Samples from 44 preterm placentas (chorionic villi) as well as matched chorion and amnion for 16 of these cases were collected for this study. These samples were profiled using the Illumina Infinium HumanMethylation850 BeadChip to measure DNA methylation (DNAm) at 866,895 CpGs across the genome. An additional 78 placental samples were utilized to independently validate the array findings by pyrosequencing. Results: Using a false discovery rate of < 0.15 and average group difference in DNAm of > 0.05, 66 differentially methylated (DM) CpG sites were identified between aCA cases and non-aCA cases in chorionic villi. For the majority of these 66 DM CpGs, the DNAm profile of the aCA cases as compared to the non-aCA cases trended in the direction of the blood cell DNAm. Interestingly, neutrophil-specific DNAm signatures, but not those associated with other immune cell types, were capable of separating aCA cases from the non-aCA cases. Conclusions: Our results suggest that aCA-associated placentas showed altered DNAm signatures that were not observed in the absence of aCA. This DNAm profile is consistent with the activation of the innate immune response in the placenta and/or reflect increase in neutrophils as a response to inflammation.
Emulation of Limited-perimeter Vector Matching Fault Localization Protocol
Creators: name: Dahbi, Abdelmounaim
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Computer Science.

description: Survivability in all-optical networks is an imperative requirement. There are two types of restoration techniques: link restoration and path restoration. Although link restoration is advantageous in terms of restoration speed and network load balancing, it requires to be preceded by an efficient fault localization procedure. This explains the importance of fault localization in all-optical networks. Limited-perimeter Vector Matching (LVM) Fault localization Protocol was designed to be fast and efficient. This thesis presents the emulation process for LVM Protocol. The emulation process consists of an all-optical network monitoring multi-layer software implementing the LVM protocol, we called it LVM Explorer. LVM Explorer provides a GUI 88 the presentation layer. The protocol is launched by switch services mapping the physical switches. The switch services are running in parallel 88 distributed processes. The main merit of the LVM Explorer is that it handles fault localization outside the physical network which is called only for alarms.
The role of mast cells in bone metabolism and bone disorders
Creators: name: Ragipoglu, Deniz
name: Dudeck, Anne
name: Haffner-Luntzer, Melanie
name: Voss, Martin
name: Kroner, Jochen
name: Ignatius, Anita
name: Fischer, Verena
Publisher: name: Universität Ulm
Year: 2020
Subjects: subject: bone disorders
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Osteoporosis
subject: Bone and bones
subject: Fracture healing
subject: Inflammation
subject: Mast cells
subject: Osteoporose
subject: Frakturheilung
subject: Entzündung
subject: Mastzelle

description: Mast cells (MCs) are important sensor and effector cells of the immune system that are involved in many physiological and pathological conditions. Increasing evidence suggests that they also play an important role in bone metabolism and bone disorders. MCs are located in the bone marrow and secrete a wide spectrum of mediators, which can be rapidly released upon activation of mature MCs following their differentiation in mucosal or connective tissues. Many of these mediators can exert osteocatabolic effects by promoting osteoclast formation [e.g., histamine, tumor necrosis factor (TNF), interleukin-6 (IL-6)] and/or by inhibiting osteoblast activity (e.g., IL-1, TNF). By contrast, MCs could potentially act in an osteoprotective manner by stimulating osteoblasts (e.g., transforming growth factor-β) or reducing osteoclastogenesis (e.g., IL-12, interferon-γ). Experimental studies investigating MC functions in physiological bone turnover using MC-deficient mouse lines give contradictory results, reporting delayed or increased bone turnover or no influence depending on the mouse model used. By contrast, the involvement of MCs in various pathological conditions affecting bone is evident. MCs may contribute to the pathogenesis of primary and secondary osteoporosis as well as inflammatory disorders, including rheumatoid arthritis and osteoarthritis, because increased numbers of MCs were found in patients suffering from these diseases. The clinical observations could be largely confirmed in experimental studies using MC-deficient mouse models, which also provide mechanistic insights. MCs also regulate bone healing after fracture by influencing the inflammatory response toward the fracture, vascularization, bone formation, and callus remodeling by osteoclasts. This review summarizes the current view and understanding of the role of MCs on bone in both physiological and pathological conditions.
First reported case in Canada of anaphylaxis to lupine in a child with peanut allergy
Creators: name: Soller, Lianne
name: La Vieille, Sebastien
name: Chan, Edmond S.
Publisher: name: BioMed Central
Year: 2018

description: Background: Lupine is a member of the legume family and is often used in many food products in Europe (e.g. pasta, pizza, sauces, etc.) as a wheat or soy substitute. Lupine cross-reacts with peanut, and cases of allergic reactions to lupine in peanut-allergic patients have been reported in Europe mainly. In contrast, lupine as an ingredient in food products is relatively new to the Canadian market. Case presentation: We describe a 10-year old boy with diagnosed peanut and tree-nut allergy, who developed anaphylaxis to lupine flour in May 2017. A few minutes after eating a pre-made pancake mix that didn’t contain any of his known allergens (peanuts, tree nuts), he developed oral pruritis followed by throat tightness, severe stomach ache, lightheadedness, cough, hoarse throat, nasal congestion, sneezing, and fatigue. He refused epinephrine, but was given cetirizine. The symptoms resolved after 3 h, but he was still unwell the following day. In a conversation between the mother and the allergist, it was determined that lupine was likely the cause of the reaction. To confirm, he was brought into clinic for skin testing to lupine. Results were consistent with lupine allergy (pancake mix: 10 × 7 mm, lupine bean: 12 × 6 mm). The family has since reported this to the Canadian Food Inspection Agency, resulting in a product recall and a consumer advisory bulletin published by Health Canada. Conclusions: This is the first reported case of allergic reaction to lupine in Canada, and highlights the need for education of Canadian families with peanut allergy as well as allergists, regarding the possibility of cross-reactivity between peanut and lupine and its new presence in the Canadian food supply. In addition, a precautionary label for those with peanut allergy who purchase products containing lupine should be considered. This case illustrates also the need for a clear mechanism for consumers and allergists to report emerging food allergens to regulatory bodies such as Health Canada.
Export Performance Perception by Managers of Family-Owned Agri-Food SMEs in Morocco: An Exploratory Case Study
Creators: name: Mohamed Abdanour
name: Noureddine AIT ERRAYS
Publisher: name: Zenodo
Year: 2024

description: The perception of export performance has been the subject of several studies in the context of developed economies, it is in this sense that we will try to understand this problem in developing countries, in this case, Morocco.

This communication will deal with the concept of export performance and particularly its perception by the managers of family agri-food SMEs in Morocco, in other words this work seeks to provide elements of answers to the following questions: How do the owner-managers of family agri-food SMEs perceive the export performance of their companies? Do the managers of these companies use the same determinants and the same variables for measuring export performance ? To answer this problem, we will undertake an exploratory study with a sample of managers of family agri-food exporting SMEs in Morocco.
Globale Landflächen und Biomasse nachhaltig und ressourcenschonend nutzen
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2013
Subjects: subject: Biomasse
subject: Landfläche
subject: Ressourcenschonung
subject: Nachhaltigkeitsstrategie
subject: Begrenzte Rohstoffe
subject: Fossiler Brennstoff
subject: Landnutzung
subject: Landwirtschaft
subject: Soil | Land

description: Weltweit verschärft sich der Druck auf Landflächen und andere Ressourcen. Ursachen hierfür sind die ressourcenintensiven Konsumweisen der Industrie- und Schwellenländer sowie die steigende Nachfrage nach Agrar- und Forstprodukten durch die globale demographische Entwicklung. Eine wachsende Weltbevölkerung benötigt mehr Nahrung, mehr nachwachsende Rohstoffe und mehr Energie. Der vorliegende Bericht gibt einen Überblick über den aktuellen Status der biomassebasierten Landnutzung und beleuchtet vorhandene und zu erwartende globale Entwicklungstrends. Er skizziert, wie eine ökologisch verträglichere und sozial gerechtere Ressourcennutzung aussehen kann und welche Prioritäten in der Produktion und Nutzung von Biomasse gesetzt werden müssen, um dieses Ziel zur erreichen. Dabei werden Handlungsansätze aufgezeigt und Politikempfehlungen zur Entwicklung einer global nachhaltigen, ressourcenschonenden Landnutzung gegeben.
Quelle: ©Almut Jering
description: Ehe die Menschen Öl, Kohle, Erdgas und Uran entdeckten und zu nutzen lernten, diente ⁠Biomasse⁠ der Deckung menschlicher Bedürfnisse in allen Lebensbereichen. Sie wird seit jeher als Nahrungs- und Futtermittel, als Brennmaterial, Baustoff, Rohstoff für Textilien sowie als Arznei genutzt. Bis zur Mechanisierung und Motorisierung der Landwirtschaft infolge der Industriellen Revolution bildeten regional weitgehend geschlossene Nährstoff- und Energiekreisläufe die Grundlage landwirtschaftlicher Biomasseproduktion. Die für die Produktion notwendige Energie (Futtermittel für Arbeitstiere und Nahrungsmittel für die menschliche Arbeitskraft) stammte aus dem Landwirtschaftssektor selbst. Mit dem technischen Fortschritt des 20. Jahrhunderts hat sich die Art der Biomasseproduktion und -nutzung stark verändert (Stichworte: Spezialisierung, zunehmend globale Arbeitsteilung und Handel). Fossile Energieträger ermöglichten die Motorisierung der Landwirtschaft und die energieintensive Produktion von Dünge- und Pflanzenschutzmitteln.
Breaking the barriers: Making ecotourism culturally sensitive in a global community
Creators: name: Donohoe, Holly Marie
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Geography.

description: This study examines the evolution of ecotourism and the emergent 'cultural turn' in the ecotourism discourse. Key ecotourism tenets are identified through content analysis of ecotourism definitions. Their salience beyond the 'Western' context (where they were developed) is identified as a significant concern in the literature and amongst professionals in the ecotourism field. Therefore, the Delphi technique is applied to capture and interpret international expertise related to cultural sensitivity and its relevancy for ecotourism goal achievement. In doing so, this research offers several contributions towards 'breaking the barriers'. First, a definition for culturally sensitive ecotourism is established on the basis of the Delphi consultations. Second, a framework for contemporary ecotourism, one that is sensitive to the now global ecotourism landscape, is introduced. Third, barriers and opportunities for establishing and implementing cultural sensitivity are identified. Fourth, the utility of these outcomes for assisting the ecotourism community to 'break the barriers' and operate with understanding and integrity, to be sensitive to local and Indigenous communities, to protect cultural heritage and living cultures, and by extension, operationalize sustainable development, is explored. This research contributes 10 an evolving understanding of the contemporary ecotourism paradigm and its emergent cultural sensitivity imperative in the cultural mosaic of our global community.
Survey of protocol reverse engineering algorithms: Decomposition of tools for static traffic analysis
Creators: name: Kleber, Stephan
name: Maile, Lisa
name: Kargl, Frank
Publisher: name: Universität Ulm
Year: 2018
Subjects: subject: Protocol reverse engineering
subject: Network security
subject: Pattern recognition
subject: DDC 004 / Data processing & computer science
subject: Statistics
subject: FOS: Mathematics
subject: Machine learning
subject: Computer networks; Security measures
subject: Pattern perception
subject: Corporate Network
subject: Statistik
subject: Mustererkennung

description: Knowledge about a network protocol to understand the communication between entities is necessary for vulnerability research, penetration testing, malware analysis, network reconnaissance, and network modeling. Traffic analysis is one approach to infer a protocol, and this approach has specific challenges, tasks, methods, and solutions. In this survey, we collect tools presented by prior research in the field of protocol reverse engineering by static traffic trace analysis. We dissect each tool to discern the individual mechanisms and the algorithms on which they are based, then categorize and contrast the mechanisms and algorithms used in static traffic trace analysis to discuss how successfully they were applied in each case. To structure our discussion about the tools, we compared classification schemes for protocol reverse engineering. We present and discuss an explicit process model for static traffic trace analysis to reveal the common structure of the decomposed tools and frameworks from previous research. Via discussions of the algorithms applied within each tool, we show relations between tools, methods, and the process for each process task. We validate our model by applying it to each of the tools, then provide an outline of the utility of protocol reverse engineering. Beginning with the process description, we deduce which solutions and algorithms have already been investigated and where challenges remain to determine how new solutions may be researched in the future. Across the entire field of protocol reverse engineering, few implementations of tools and frameworks are publicly available, which remains a prevalent problem.
Estimation of dietary intake of bis(2-ethylhexyl)phthalate (DEHP) by consumption of food in the German population
Creators: name: (:Unkn) Unknown
Publisher: name: My University
Year: 2013
Subjects: Diethylhexylphthalat
Exposition
Lebensmittelkontamination
Probabilistische Methode
Bundesrepublik Deutschland

description: In the study presented here, we evaluated the exposure of the German population aged 14-80 years tobis(2-ethylhexyl)phthalate (DEHP) from consumption of food by means of deterministic and probabilisticestimations. The study was performed on the basis of an extensive review of literature from around theworld reporting measured data on DEHP in food, as well as official German food control data. Only datafrom individual measurements were considered and used for fitting of distributions. A wide range ofconcentrations in non-representative samples are reported in the literature. On the basis of the availableDEHP concentration data, 37 food categories were characterized which covered all major food classes.Food consumption data were taken from the diet history interviews of the German National NutritionSurvey II (Nationale Verzehrsstudie II) which was performed in 2005/2006 in a representative studypopulation of 15,371 and is the most recent data source of this kind in Germany. Average DEHP intakewas estimated deterministically using data on measured concentrations in food (medians and means)and food consumption (means). A total dietary exposure to DEHP of 3.6 (median based) and 9.3 g/kg ofBW per day (based on mean values) was estimated deterministically. In addition, distributions of bothconcentrations and consumption figures were fitted using the @RISK best fit tool for further probabilisticestimations. This approach resulted in estimates within the same range: the estimated median DEHPintake in the whole population (both non-consumers and consumers of the foods considered) was 10.2,the arithmetic mean 14.0 and the 95th percentile 28.6 g/kg of BW per day. The respective estimatesfor consumers only were 12.4, 18.7 and 36.5 g/kg of BW per day. These results demonstrate that theprobabilistic approach is able to estimate broader ranges of exposure even when using data representingan average intake. Moreover, it reflects the uncertainties of the estimation due to insufficient analyticaldata on concentrations of DEHP in food.
© 2013 Published by Elsevier GmbH
title: Transition structures and timing of transfer from paediatric to adult-based care after kidney transplantation in Germany
title: a qualitative study
titleType: Subtitle
Creators: name: Pruefe, Jenny
name: Dierks, Marie-Luise
name: Bethe, Dirk
name: Oldhafer, Martina
name: Muether, Silvia
name: Thumfart, Julia
name: Feldkoetter, Markus [U.A.]
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Objectives: It is known that transition, as a shift of care, marks a vulnerable phase in the adolescents’ lives with an increased risk for non- adherence and allograft failure. Still, the transition process of adolescents and young adults living with a kidney transplant in Germany is not well defined. The present research aims to assess transition-relevant structures for this group of young people. Special attention is paid to the timing of the process. Setting: In an observational study, we visited 21 departments of paediatric nephrology in Germany. Participants were doctors (n=19), nurses (n=14) and psychosocial staff (n=16) who were responsible for transition in the relevant centres. Structural elements were surveyed using a short questionnaire. The experiential viewpoint was collected by interviews which were transcribedverbatim before thematic analysis was performed. Results: This study highlights that professionals working within paediatric nephrology in Germany are well aware of the importance of successful transition. Key elements of transitional care are well understood and mutually agreed on. Nonetheless, implementation within daily routine seems challenging, and the absence of written, structured procedures may hamper successful transition. Conclusions: While professionals aim for an individual timing of transfer based on medical, social, emotional and structural aspects, rigid regulations on transfer age as given by the relevant health authorities add on to the challenge. Trial registration number: ISRCTN Registry no 22988897; results (phase I) and pre-results (phase II).