cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Monocytes to lymphocytes multiplying platelets ratio as an early indicator of acute kidney injury in cardiac surgery with cardiopulmonary bypass: a retrospective analysis
Creators: name: Li, Qian
name: Lv, Hong
name: Chen, Yuye
name: Shen, Jingjia
name: Shi, Jia
name: Yan, Fuxia
name: Wang, Sheng
name: Zhou, Chenghui
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Science Policy

description: The monocyte-to-lymphocyte multiplying platelets ratio (MLPR) is a novel systemic inflammatory marker, deriving from the monocyte-to-lymphocyte ratio (MLR). However, the link between MLPR and acute kidney injury following cardiac surgery (CSA-AKI) with cardiopulmonary bypass (CPB) has not been investigated yet. We comprehensively explored the potential linear and nonlinear relationship between MLPR or MLR and CSA-AKI. Data of patients who underwent cardiac surgery with CPB between December 2018 and April 2021 were retrospectively collected at Fuwai Hospital, Beijing, China. MLPR was defined as monocyte count (×109/L) × 1000/(lymphocyte count (×109/L) × platelets (×109/L)). MLR was defined as monocyte count (×109/L)/lymphocyte count (×109/L). Logistic regression and restricted cubic spline (RCS) were used for linear and nonlinear analysis. The primary outcome was postoperative AKI within 48 h of after cardiac surgery. Of the 2420 patients screened, 2387 eligible patients were enrolled in the final analysis; the mean age was 54.7 years, and 1501 [62.9%] were men. The incidence of AKI was 25.8%. Logistic regression showed that MLPR (odds ratio [OR] = 1.31, 95% confidence interval [CI]: 1.16–1.48, p < .001) and MLR (OR = 3.06, 95% CI: 1.29–7.29, p = .012) were independent risk factors for AKI. Moreover, in the RCS model with adjustment for age (median: 56), female sex, and history of diabetes, a significant statistical difference was detected between preoperative MLPR, MLR, and AKI (p for non-linearity <.001). The subgroup analyses revealed similar results. The study revealed a nonlinear relationship between MLPR and MLR with AKI. MLPR exhibited a J-shaped curve, and MLR showed a favorable S-shaped curve in relation to AKI. Particularly, MLPR emerges as a promising clinical composite index for early CSA-AKI prediction. These findings emphasize the significance of MLPR as a valuable tool in clinical practice for timely identification and management of CSA-AKI.
Additional file 1 of Synthesis and characterization of green phenolic resin with olive oil mill wastewater
Creators: name: Özbay, Günay
name: Ayrilmis, Nadir
name: Ahmad, Muhammad Syarhabil
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Additional file 1. Materials and methods description.
Gayet_Supplemental_Material_Sections_S5-S8 – Supplemental material for Scenes Modulate Object Processing Before Interacting With Memory Templates
Creators: name: Gayet, Surya
name: Peelen, Marius V.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, Gayet_Supplemental_Material_Sections_S5-S8 for Scenes Modulate Object Processing Before Interacting With Memory Templates by Surya Gayet and Marius V. Peelen in Psychological Science
Kickass Companies: Leveraging business models with great leadership
Creators: name: Brøndum, Kristian
name: Nielsen, Christian
name: Tange, Kim
name: Laursen, Frans
name: Oehlenschläger, Jesper
Publisher: name: Journal of Business Models
Year: 2015

description: This paper is based on a study of 755 Danish SMEs and further in-depth case studies of 12 of these. Its
objective was to identify a model of components and relationships among the very best, most efficient,
high-performing SMEs. We call these Kickass Companies. The result is a model made up of six interrelated dimensions, which together illustrate what makes up a Kickass Company:
• You need willpower
• You need to be there for your customers
• You strive to be the best
• Success is a “we thing”
• You need to be able to accelerate
• Use motivating KPIs

Following these six dimensions might not be a guarantee of success, and not all components will be implementable in all types of companies. However, the empirical evidence here suggests that, if companies think along these lines of doing business, their probability of success will be higher than otherwise.
description: Journal of Business Models, Vol 3 No 1 (2015): Journal of Business Models
Magnitude and precision of absolute blood volume estimated during hemodialysis
Creators: name: Abohtyra, Rammah
name: Vincent, Tyrone
name: Schneditz, Daniel
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health

description: Background: Management of body fluid volumes and adequate prescription of ultrafiltration (UF) remain key issues in the treatment of chronic kidney disease patients.Objective: This study aims to estimate the magnitude as well as the precision of absolute blood volume (Vb) modeled during regular hemodialysis (HD) using standard data available with modern dialysis machines.Methods: The estimation utilizes a two-compartment fluid model and a mathematical optimization technique to predict UF-induced changes in hematocrit measured by available on-line techniques. The method does not rely on a specific hematocrit sensor or a specific UF or volume infusion protocol and uses modeling and prediction tools to quantify the error in Vb estimation.Results: The method was applied to 21 treatments (pre-UF body mass: 65.57±13.44 kg, UF-volume: 3.99±1.14 L) obtained in ten patients (4 female). Pre-HD Vb was 5.4±0.53 L with an average coefficient of variation of 9.8% (range 1 to 22%). A significant moderate correlation was obtained when Vb was compared to a different method applied to the same data set (r = 0.5). Specific blood volumes remained above the critical level of 65 mL/kg in 17 treatments (80.9%).Conclusion: The method offers the opportunity to detect critical blood volumes during HD and to judge the quality and reliability of that information based on the precision of the Vb estimate.
Dynamics of Openness in SMEs: A Business Model and Innovation Strategy Perspective
Creators: name: Iivari, Marika Miriam
Publisher: name: Journal of Business Models
Year: 2015

description: Purpose: In order to explore the dynamics of openness within SMEs, this study investigates how business model transformation relates to innovation strategy transformation.

Design/Methodology/Approach: This research is conducted as a longitudinal qualitative single case study in order to fully follow transformation as a process.

Findings: This research revealed that openness in SMEs is not about continuously increasing the level of openness, but SMEs can also begin to close their innovation strategy, even though the business model stays open. The level of openness varies based on strategic openness.

Research limitations/implications: This study emphasizes that openness needs to be viewed as a continuum, where the level of openness may fluctuate during transformation. Furthermore, openness in business models and openness in innovation indeed are separate phenomena.

Practical implications: Having an understanding how strategic openness guides business model transformation enables practitioners to better utilize open innovation as an innovation strategy.

Originality/value: Through focusing on the relationship between business model transformation and innovation strategy transformation, we broaden the discussion on the dynamics of openness within SMEs.
description: Journal of Business Models, Vol 3 No 2 (2015): Journal of Business Models
Comparison of feasibility and effectiveness of tunneled dialysis catheter placement with or without DSA guidance: a propensity score-matched cohort study
Creators: name: Shang, Yiwei
name: Pan, Shujun
name: Jin, Chen
name: Zheng, Danna
name: Xu, Xiujun
name: Zhu, Bin
name: Zhao, Li
name: Jin, Juan
name: He, Qiang
name: Shen, Xiaogang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Space Science
subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Cancer

description: In some resource-limited regions, the placement of tunneled dialysis catheters (TDC) is often preferred under ultrasound guidance rather than fluoroscopy. This study compared ultrasound-and digital subtraction angiography-guided (DSA)-guided TDC in renal replacement therapy. This retrospective cohort study included all TDC placements performed at our hospital between January 2020 and October 2022. We utilized 1:1 propensity score matching (PSM) to balance the demographic and clinical characteristics of the DSA-guided and ultrasound-guided groups. Dialysis prescriptions and actual dialysis completion were assessed using intraclass correlation coefficients (ICC). Multivariable logistic regression analyses determined the risk factors for early termination of dialysis. The differences in adverse events, catheter function, and catheter tip position were evaluated between the two groups. The study included 261 patients (142 in the DSA-guided group and 119 in the ultrasound-guided group). After PSM, 91 patients were included in each group, with no significant baseline differences (p > .1). Both groups achieved adequate catheter blood flow and ultrafiltration volumes without deviations from dialysis prescriptions (ICC ≥ 0.75). The DSA-guided group had fewer early dialysis terminations than the ultrasound-guided group (3.3 vs. 12.0%, p = .026). The position of the catheter tip in the right atrium was more consistent in the DSA-guided group (100 vs. 74.2%, p < .001). Hemodialysis catheters inserted under DSA guidance exhibited superior performance compared to those inserted under ultrasound guidance, primarily due to more accurate catheter tip positioning. DSA guidance is recommended when ensuring optimal catheter tip placement.
Business Model Innovation: Development, Concept and Future Research Directions
Creators: name: Wirtz, Bernd
name: Göttel, Vincent
name: Daiser, Peter
Publisher: name: Journal of Business Models
Year: 2016

description: Purpose: Although business model innovation (BMI) has gained substantial importance in recent years, there is still a limited understanding of this phenomenon. Yet, the corresponding scholarly literature has previously been characterized by a heterogeneous comprehension of the concept. This situation demands an analysis that synthesizes current scienti c knowledge, uncovers research gaps and underdeveloped areas, and estab- lishes a solid foundation for future research.

Design: The study applies an extensive quantitative and qualitative analysis of extant BMI literature, making the concept more transparent and manageable for science and management.

Findings: The study presents a set of yielding de nitions of the extant BMI literature and an integrated de ni- tion to promote a common understanding of BMI. In addition, it classi es the eld into six particular research areas. Given the identi ed dominance of exploratory research designs, future research should put more em- phasis on well-founded conceptual articles that stabilize and consolidate basic research as well as con rma- tory quantitative empirical investigations.

Research limitations / Implictions: Given the database-centered, eclectic nature of the analytical approach, it is unlikely that every available and applicable scienti c publication is included in the analysis. Furthermore, the classi cation of the studies according to certain criteria leads to a loss of information and sometimes can- not be conducted free of doubt since studies occasionally touch multiple criteria.

Originality / Value: Against the background of the study’s focus on BMI, its comparably broad literature basis, and its quantitative and qualitative analysis approach, which provides straightforward recommendations for future research, the study caters an original contribution to the eld.
description: Journal of Business Models, Vol 4 No 1 (2016): 2016 open issue
Additional file 5 of Impact of different CAD/CAM materials on internal and marginal adaptations and fracture resistance of endocrown restorations with: 3D finite element analysis
Creators: name: El-Farag, Shaimaa Ahmed Abo
name: Elerian, Fatma Abdallah
name: Elsherbiny, Abdallah Ahmed
name: Abbas, Mahy Hassouna
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Cell Biology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy
Hematology

description: Additional file 5. Raw Data of Fracture resistance test of Endocrowns.
Old but sexy: Value creation of old technology-based businesses models
Creators: name: Beckmann, Oke Christian
name: Royer, Susanne
name: Schiavone, Francesco
Publisher: name: Journal of Business Models
Year: 2016

description: The purpose of this study is to contribute to a better understanding of the strategic and organisational con gurations that companies can use to generate value with product-market systems and their busi- ness models that have been dominant in the past but forced back into niche positions by innovation.

The former dominant music format vinyl was rapidly substituted after the introduction of digital music. However, still nowadays some customers use and buy old technology-based products – vinyl sales boom again since 2007. Due to the two-sided nature of the market, customers have to get access to complementary goods. We are thus interested in technologies which have been outdated by the emergence of new technologies. The originality lies in the combination of the two areas: business models and old technologies. Furthermore, vinyl is an example not analysed in depth by scholars so far.

We approached this by undertaking an in-depth literature review to generate hypotheses regarding the value-adding activities of old-technology based businesses as a basis for further research in this area. In addition the paper gives insights into the constellations to be expected over time for old technology-based businesses models in platform markets.

We here focus on a neglected topic in the strategy literature which, however, bears relevance for many businesses locked into product-market systems which make it hard for them to (completely) switch to a new technology emerging in the market. It is especially valuable to describe the consequences in a systematic fashion.
description: Journal of Business Models, Vol 4 No 2 (2016): SPECIAL ISSUE: SUSTAINABILITY AND SCALABILITY OF BUSINESS MODELS
Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study
Creators: name: Wang, Dawei
name: Shi, Feng
name: Zhang, Dingguo
name: Zhang, Lin
name: Wang, Hui
name: Zhou, Zijian
name: Zhu, Yu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Molecular Biology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: To investigate the association between atherogenic index of plasma (AIP) and kidney stones (KS) occurrence and recurrence. Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2014. Non-pregnant adults who provided complete information on AIP and KS were included in the analyses. AIP was calculated as log (triglyceride/high-density lipoprotein cholesterol). KS was ascertained with questionnaires. Weighted multivariable logistic regression model and restricted cubic spline (RCS) were applied to examine the associations between AIP and KS occurrence and recurrence. A total of 6488 subjects (weighted mean age 43.19 years and 49.26% male) with a weighted mean AIP of 0.66 were included in this study. The multivariable-adjusted OR for nephrolithiasis occurrence across consecutive tertiles was 1.00 (reference), 1.21 (95% CI: 0.90–1.62), and 1.85 (95% CI: 1.39–2.48), respectively. Moreover, each SD increment of AIP was associated with a 50% (OR:1.50, 95% CI: 1.25–1.81) higher risk of nephrolithiasis recurrence. RCSs showed significant and linear dose-response relationships between AIP and nephrolithiasis occurrence (p-overall = 0.006, p-nonlinear = 0.689) and recurrence (p-overall = 0.001, p-nonlinear = 0.848). The positive associations between AIP and nephrolithiasis occurrence and recurrence persisted in sensitivity analyses, suggesting the robustness of the results. In the current US nationally representative cross-sectional study, AIP was positively associated with KS occurrence and recurrence.
Additional file 1 of A randomized controlled pilot study of daily intravenous ketamine over three days for treatment-resistant depression
Creators: name: Pattanaseri, Keerati
name: Lortrakul, Juthawadee
name: Jaisin, Kankamol
name: Srifuengfung, Maytinee
name: Sa-nguanpanich, Naratip
name: Viravan, Natee
name: Pariwatcharakul, Pornjira
name: Makarasara, Wattanan
name: Ratta-apha, Woraphat
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Mental Health

description: Supplementary Material 1
The efficacy and safety of difelikefalin for pruritus in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials
Creators: name: Saeed, Abdallah
name: Elshnoudy, Iman Abdelhady
name: Khlidj, Yehya
name: Radwan, Radwa
name: Kamal, Mariam
name: Hamdi, Mahmoud
name: Alsaid, Abdullah
name: Turkmani, Mustafa
name: Abuelazm, Mohamed
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Chronic kidney disease–associated pruritus (CKD-ap) is a common complication that negatively affects the quality of life. Difelikefalin has emerged as a novel FDA-approved drug to manage CKD-ap. This systematic review and meta-analysis will assess the efficacy and safety of Difelikefalin versus placebo to manage CKD-ap. PubMed, Scopus, WOS, Central, and Embase were systematically searched until November 2023. RevMan was used to perform meta-analysis. Quality assessment was conducted using the Cochrane RoB 2.0 tool. Results were reported as risk ratio (RR) and mean difference (MD) with a 95% confidence interval (CI). PROSPERO ID: (CRD42023485979). Five RCTs with a total of 896 participants were included. Difelikefalin significantly decreased the weekly mean WI-NRS score (MD: −0.99 [−1.22, −0.75], p ˂ .00001), 5-D itch scale total score (MD: −1.51 [−2.26, −0.76], p > .0001), and Skindex-10 total score (MD: −7.39 [−12.51, −2.28], p = .005), but showed significantly higher adverse events (RR: 1.26 [1.03, 1.55], p = .03), versus placebo. However, there was no significant difference between both groups in serious adverse events (RR: 1.42 [0.78, 2.57], p = .25) or death (RR: 0.81 [0.19, 3.34], p = .77). Difelikefalin appears to be a promising agent for the management of CKD-induced pruritus in patients with end-stage renal disease. However, evidence is still underpowered due to the paucity of the current data; therefore, more robust RCTs are required to confirm the benefit of Difelikefalin.
A two-part exploration of cognitive function in schizophrenia spectrum disorder: characterising heterogeneity and the central muscarinic system
Creators: name: Carruthers, Sean
Publisher: name: Swinburne
Year: 2024

description: Schizophrenia spectrum disorder is a debilitating and lifelong psychiatric illness. Cognitive dysfunction is commonly considered a hallmark feature that is said to be experienced by all with the disorder. This body of research examined the considerable variability in cognitive impairment experienced by those with schizophrenia spectrum disorder and one of the potential underlying causes, the muscarinic system. Through a more in-depth understanding of the extent of cognitive impairment and the underlying causes, better treatments can be developed to improve the quality of life of those living with schizophrenia spectrum disorder.
The Unfolding of Value Sources During Online Business Model Transformation
Creators: name: Hoßbach, Nadja
name: Wiener, Martin
name: Saunders, Carol S.
Publisher: name: Journal of Business Models
Year: 2016

description: Purpose: In the magazine publishing industry, viable online business models are still rare to absent. To prepare for the ‘digital future’ and safeguard their long-term survival, many publishers are currently in the process of transforming their online business model. Against this backdrop, this study aims to develop a deeper understanding of (1) how the different building blocks of an online business model are transformed over time and (2) how sources of value creation unfold during this transformation process.

Methodology: To answer our research question, we conducted a longitudinal case study with a leading German business magazine publisher (called BIZ). Data was triangulated from multiple sources including interviews, internal documents, and direct observations.

Findings: Based on our case study, we nd that BIZ used the transformation process to differentiate its online business model from its traditional print business model along several dimensions, and that BIZ’s online business model changed from an efficiency- to a complementarity- to a novelty-based model during this process.

Research implications: Our findings suggest that different business model transformation phases relate to different value sources, questioning the appropriateness of value source-based approaches for classifying business models.

Practical implications: The results of our case study highlight the need for online-offline business model differentiation and point to the important distinction between service and product differentiation.

Originality: Our study contributes to the business model literature by applying a dynamic and holistic perspective on the link between online business model changes and unfolding value sources.
description: Journal of Business Models, Vol 4 No 2 (2016): SPECIAL ISSUE: SUSTAINABILITY AND SCALABILITY OF BUSINESS MODELS
Additional file 1 of Artificial Intelligence to support ethical decision-making for incapacitated patients: a survey among German anesthesiologists and internists
Creators: name: Benzinger, Lasse
name: Epping, Jelena
name: Ursin, Frank
name: Salloch, Sabine
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Information Systems not elsewhere classified
Developmental Biology
Cancer
Science Policy

description: Supplementary Material 1.
Toward Ecosystemic Business Models in the Context of Industrial Internet
Creators: name: Iivari, Marika Miriam
name: Ahokangas, Petri
name: Komi, Marjaana
name: Tihinen, Maarit
name: Valtanen, Kristiina
Publisher: name: Journal of Business Models
Year: 2016

description: Purpose: This study explores business models within a particular domain of Industrial Internet. Design/Methodology/Approach: Building from theory, this study is conceptual in nature.

Findings: This paper presents a business model framework for understanding the dynamics of value co-creation and co-capture from lifecycle and ecosystem configuration point of view.

Research limitations/implications: This study stresses the need to understand how the integrated, co-dependent processes of value co-creation and co-capture influence on business models of individual firms in co-evolving business ecosystems.

Practical implications: To fully benefit from the mutually connected opportunities enabled by IoT, it is important for firms to position themselves within the ecosystem in terms of the stage of product or service life cycle as well as the scale and scope of ecosystem configuration.

Originality/value: The originality of this research thus relates to expanding the business model literature from ecosystemic perspective.
description: Journal of Business Models, Vol 4 No 2 (2016): SPECIAL ISSUE: SUSTAINABILITY AND SCALABILITY OF BUSINESS MODELS
Futures Business Models for an IoT Enabled Healthcare Sector: A Causal Layered Analysis Perspective
Creators: name: Gomes, Julius Francis
name: Moqaddemerad, Sara
Publisher: name: Journal of Business Models
Year: 2016

description: Purpose: To facilitate futures business research by proposing a novel way to combine business models as a conceptual tool with futures research techniques.

Design: A futures perspective is adopted to foresight business models of the Internet of Things (IoT) enabled healthcare sector by using business models as a futures business research tool. In doing so, business models is coupled with one of the most prominent foresight methodologies, Causal Layered Analysis (CLA). Qualitative analysis provides deeper understanding of the phenomenon through the layers of CLA; litany, social causes, worldview and myth.

Findings: It is di cult to predict the far future for a technology oriented sector like healthcare. This paper presents three scenarios for short-, medium- and long-term future. Based on these scenarios we also present a set of business model elements for different future time frames. This paper shows a way to combine business models with CLA, a foresight methodology; in order to apply business models in futures business research. Besides offering early results for futures business research, this study proposes a conceptual space to work with individual business models for managerial stakeholders.

Originality / Value: Much research on business models has offered conceptualization of the phenomenon, innovation through business model and transformation of business models. However, existing literature does not o er much on using business model as a futures research tool. Enabled by futures thinking, we collected key business model elements and building blocks for the futures market and ana- lyzed them through the CLA framework.
description: Journal of Business Models, Vol 4 No 2 (2016): SPECIAL ISSUE: SUSTAINABILITY AND SCALABILITY OF BUSINESS MODELS
Additional file 1 of Metformin induces ZFP36 by mTORC1 inhibition in cervical cancer-derived cell lines
Creators: name: De la Cruz-López, Karen Griselda
name: Alvarado-Ortiz, Eduardo
name: Valencia-González, Heriberto A.
name: Beltrán-Anaya, Fredy Omar
name: Zamora-Fuentes, José María
name: Hidalgo-Miranda, Alfredo
name: Ortiz-Sánchez, Elizabeth
name: Espinal-Enríquez, Jesús
name: García-Carrancá, Alejandro
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1.
Inflammatory indexes and anemia in chronic kidney disease: correlation and survival analysis of the National Health and Nutrition Examination Survey 2005–2018
Creators: name: Fu, Shaojie
name: Huang, Jingda
name: Feng, Zhenbang
name: Wang, Haitao
name: Xu, Hongzhao
name: Wu, Meiyan
name: Ma, Fuzhe
name: Xu, Zhonggao
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: There is currently no research on the correlation between novel inflammatory indexes systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and the risk of anemia in chronic kidney disease (CKD) population, as well as survival analysis in CKD with anemia. This investigation encompassed 4444 adult subjects out of the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2018. The study utilized multi-variable logistic regression to assess the relationship between SII, NLR, PLR, and anemia risk occurrence in CKD population. Survival differences in CKD patients with anemia, based on varying levels of SII, NLR, and PLR were evaluated employing Kaplan–Meier and Cox proportional hazards models. The adjusted logistic regression model demonstrates that SII, NLR, and PLR are associated with the risk of anemia occurrence in CKD population. Kaplan–Meier’s analysis reveals significant differences in survival rates among CKD patients with anemia stratified by NLR levels. The adjusted Cox proportional hazards model shows that the higher NLR group has a 30% elevated risk of all-cause mortality contrasted with lower group (hazard ratio, HR: 1.30, confidence interval (CI) [1.01, 1.66], p value <.04). Restricted cubic spline (RCS) demonstrates no nonlinear relationship between NLR and all-cause mortality. Lastly, sub-cohort analysis indicates that in populations with diabetes, hypertension, and hyperuricemia, NLR levels have a greater impact on all-cause mortality. Controlling inflammation may reduce the occurrence of anemia in CKD populations, with NLR serving to be a potential prognostic indicator for survival results within CKD patients suffering from co-morbid anemia.
Additional file 1 of Prolonged administration of the granisetron transdermal delivery system reduces capecitabine plus oxaliplatin regimen induced nausea and vomiting
Creators: name: Wang, Cong
name: Jiang, Zhansheng
name: Zhang, Jie
name: Zhuang, Yan
name: Sun, Lining
name: Zhang, Jing
name: Quan, Manman
name: Lan, Lan
name: Li, Yanwei
name: Wang, Bin
name: Pan, Zhanyu
name: Yan, Zhuchen
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Pharmacology
Science Policy

description: Supplementary Material 1
Development and validation of a predictive model for acute kidney injury in patients with ureterolithiasis
Creators: name: Jiang, Yufeng
name: Zhang, Jingcheng
name: Ainiwaer, Ailiyaer
name: Liu, Yuchao
name: Li, Jing
name: Zhou, Liuliu
name: Yan, Yang
name: Zhang, Haimin
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Cell Biology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mathematical Sciences not elsewhere classified
Developmental Biology
Science Policy

description: This study aims to identify risk factors for acute kidney injury (AKI) in patients with ureterolithiasis and to develop a predictive model for early AKI detection in this population. A retrospective analysis was conducted on data from 1,016 patients with ureterolithiasis who presented to our outpatient emergency department between January 2021 and December 2022. Using multifactorial logistic regression, we identified independent risk factors for AKI and constructed a nomogram to predict AKI risk. The predictive model’s efficacy was assessed through the area under the ROC curve, calibration curves, Hosmer-Lemeshow (HL) test, and decision curve analysis (DCA). AKI was diagnosed in 18.7% of the patients. Independent risk factors identified included age, fever, diabetes, hyperuricemia, bilateral calculi, functional solitary kidney, self-medication, and prehospital delay. The nomogram demonstrated excellent discriminatory capabilities, with AUCs of 0.818 (95% CI, 0.775–0.861) for the modeling set and 0.782 (95% CI, 0.708–0.856) for the validation set. Both calibration curve and HL test results confirmed strong concordance between the model’s predictions and actual observations. DCA highlighted the model’s significant clinical utility. The predictive model developed in this study provides clinicians with a valuable tool for early identification and management of patients at high risk for AKI, thereby potentially enhancing patient outcomes.
New imidazole-Schiff base compounds for environmentally friendly anticorrosion protection in industrial pickling of mild steel
Creators: name: Daoudi, Walid
name: Chaouiki, Abdelkarim
name: Mahamdi, Mohammed El
name: Zaidi, Kaoutar
name: Dagdag, Omar
name: Aouinti, Abdelouahad
name: Ko, Young Gun
name: Abboud, Mohamed
name: Oussaid, Adyl
name: Aatiaoui, Abdelmalik El
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified

description: As part of the development of a new organic entity, we synthesized a new series of Schiff bases belonging to the imidazo[1,2-a]pyridine (IMP) family, named: (E)-2-methoxy-4-(((2-phenylimidazo[1,2-a]pyridin-3-yl)imino)methyl)phenol(IM1) and (E)-4-(((2-phenylimidazo[1,2-a]pyridine-3-yl)imino)methyl)phenol (IM2). Molecular structures were confirmed through chemical analyses, including nuclear magnetic resonance (NMR) and mass spectroscopy. In order to develop new organic ligands to inhibit mild steel corrosion in 1M HCl solution, various weight loss and electrochemical methods, such as electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization (PDP), along with surface visualization through scanning electron microscopy (SEM) and atomic force microscopy (AFM), were employed. EIS results revealed excellent inhibition by compounds IM1 and IM2 (98% and 92%, respectively) at a concentration of 1 mM. These findings were supported by the observation of a protective layer formation during prolonged immersion of mild steel in a corrosive solution, with or without inhibitors. Finally, theoretical studies such as density functional theory (DFT) and molecular dynamics simulations were conducted to explore the adsorption behaviour of inhibitors IM1 and IM2 on the iron surface, providing insight into the inhibitor-metal interaction during the adsorption process.
The effectiveness of nirmatrelvir/ritonavir regimen in hospitalized renal transplant patients with prolonged COVID-19 infection: a multicenter clinical experience
Creators: name: Zhang, Huanxi
name: Wu, Wenrui
name: Zheng, Yitao
name: Fu, Qian
name: Chen, Peisong
name: Li, Jianyi
name: Wu, Zixuan
name: Gu, Jincui
name: Li, Jun
name: Liu, Longshan
name: Wu, Chenglin
name: Long, Sizhe
name: Xu, Bowen
name: Ling, Liuting
name: Fu, Yingxin
name: Wang, Changxi
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Effectiveness of nirmatrelvir/ritonavir (NR) in kidney transplant recipients (KTRs) infected COVID-19 for more than 5 days has not been evaluated. In this multicenter retrospective study, 85 KTRs with COVID-19 were enrolled, including 50 moderate, 21 severe, and 14 critical patients. The median time from onset to starting NR treatment was 14 (IQR, 11–19) days. Before NR treatment, 96.5% patients reduced use of antimetabolites. They also stopped using calcineurin inhibitors (CNI) 12–24 hours before NR treatment, with CNI concentrations well-controlled during NR treatment. The use of intravenous corticosteroids increased with COVID-19 severity. The median time to reach viral negative conversion was 5 (IQR, 4–8) days for all patients. For moderate and severe COVID-19 patients, they had a low rate of ICU admission (1.4%), exacerbation requiring upgraded oxygen therapy (5.6%), and dialysis (2.8%); no intubation and mechanical ventilation, and no deaths were observed. Patients with critical COVID-19 had a low mortality rate (7.1%). A regimen including NR for clearing SARS-CoV-2 along with reducing immunosuppressants and using intravenous corticosteroids is associated with lower rates of exacerbation and mortality in KTRs who have moderate to critical SARS-CoV-2 infection and the virus still present after 5 days.
Additional file 1 of Impact of different CAD/CAM materials on internal and marginal adaptations and fracture resistance of endocrown restorations with: 3D finite element analysis
Creators: name: El-Farag, Shaimaa Ahmed Abo
name: Elerian, Fatma Abdallah
name: Elsherbiny, Abdallah Ahmed
name: Abbas, Mahy Hassouna
Publisher: name: figshare
Year: 2024
Subjects: Space Science
Medicine
Cell Biology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy
Hematology

description: Additional file 1. Raw data for marginal adaptation test of Vita Enamic Endocrowns.
Additional file 1 of The Essential and Optimal Analgesic and Anti-Inflammatory Medicines for Athletes at the Olympic Games
Creators: name: Stuart, Mark
name: Farooq, Mohammed
name: Thomas, Trudy
name: Mohamed-Ali, Nada
name: Al-Maadheed, Mohammed
name: Mohamed-Ali, Vidya
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1
Aqueous and Alcohol Extraction Of Plant (Glycyrrhiza glabra) And Activity Study Against Bacteria and Cancer (Cell Line RD)
Creators: name: Al-Obaidi, Omar Hamad Shehab
Publisher: name: European Chemical Bulletin
Year: 2013

description: Isolation had been done for active substances from Glycyrrhiza glabra plant such as Saponins , volatile oils and Tannins. The percentage in form was (41.1%), ( 2.5%) and (13.2%) respectively. As well as the appointment of some mineral elements in the Glycyrrhiza glabra seeds like sodium,  calcium and potassium and the concentration in the sample was (203)ppm, (176) ppm, (181) ppm, respectively, measured by using Flame Spectrometer. Also a study of anti-bacterial activity of extracts from Glycyrrhiza glabra using two types of pathogenic bacteria Escherichia Coli and aurous Staphylococcus showed the ability of inhibition for all different extracts by vary inhibition diameters for different active substances, concentrations and bacteria. One type of cancer cellular line used to study the effect of Glycyrrhiza glabra extracts (after the chemical assay) were studied on the  growth of Rhabdomyo sarcomas (RD) cell line in human by using in vitro system and  compared with anticancer drug cisplatin (cis-pt)  as a positive control.  The cancer cell were treated with different concentration for each of the three treatments and cis-pt after 72 hr. exposure time. The cytotoxic activity was tested by inhibition rate as parameter. The results showed significant differences (p<0.05) for each three treatments when the inhibition rates were increased. There was strong correlation between the three treatments and the different concentrations in comparison with cisplatin.
description: European Chemical Bulletin, Vol 3, No 2 (2014): European Chemical Bulletin
Low - temperature melt for preparation of aluminum corrosion-resistant and heat-stable electroplatings
Creators: name: Gasviani, Nodari
name: Kipiani, Gulnara
name: Abazadze, Lia
name: Gasviani, Sergo
name: Kokilashvili, Raul
Publisher: name: European Chemical Bulletin
Year: 2013

description: The composition of the melt was elaborated in which, primarily in a practice, the preparation of aluminum electroplatings at low - temperatures: 95-1100C is possible on hardware and steels: СТ-3, Х-18 and СТ-40 as well as on screw-profile hardware (bolts, nuts), manufactured from steels 25ХМФ and 35МФ.

Optimal conditions of the process of plating preparation and electrochemical parameters were determined. The effect of various metals-modifiers (Pb, Sn, Bi, Mn, Zr, Cr) on plating process and quality was studied.
description: European Chemical Bulletin, Vol 3, No 2 (2014): European Chemical Bulletin
Smith_Online_Appendix – Supplemental material for Group-Based Emotions Over Time: Dynamics of Experience and Regulation
Creators: name: Smith, Eliot R.
name: Mackie, Diane M.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Smith_Online_Appendix for Group-Based Emotions Over Time: Dynamics of Experience and Regulation by Eliot R. Smith and Diane M. Mackie in Personality and Social Psychology Bulletin
ELECTROCHEMICAL METHOD OF GOLD EXTRACTION FROM THE RESIDUES OF VACUUM-THERMAL TREATMENT OF GOLD-CONTAINING ANTIMONY  ORES OF  ZOPKHITO( DEPOSIT)
Creators: name: Gagnidze, Tsisana
name: Bagdavadze, Jondo
name: Chagelishvili, Rusudan
name: Mamporia, Manana
name: Tsiskaridze, Zurab
name: Kandelaki, Aleksi
Publisher: name: European Chemical Bulletin
Year: 2013

description: The possibility of gold extraction from the residues of vacuum-thermal treatment of the concentrate of gold-containing antimony ore of Zopkhito (deposit) has been established by eco-safe electrochemical method.

The effect of main technological parameters on the process of electrochemical leaching of the residues has been studied in the presence of selective complex-former- thiourea in chloride system and optimal conditions of leaching were established providing the gold extraction from gold-containing residues by 82-90% in the conditions of so-called “soft” oxidation without release of molecular chlorine at the anode and eco-contamination.

Continuous technological process of electrochemical leaching of the residues of gold-containing antimony ore and electrochemical reactor for realization of this process are proposed.

Key words: electrochemical processing, gold-containing ores, gold extraction
description: European Chemical Bulletin, Vol 3, No 2 (2014): European Chemical Bulletin
Comment on PRODUCTION OF DICALCIUM PHOSPHATE
Creators: name: Habashi, Fathi
name: Atbir, Ali
Publisher: name: European Chemical Bulletin
Year: 2014

description: We became aware of the article, “Production of Calcium Monohydrogenphosphate from Sebaiya Phosphate Ore Leaching by Nitric Acid” published in Eur. Chem. Bull. 2013, 2(10), 752-757. We do not recommend using dicalcium phosphate prepared by this method as animal feed unless uranium and fluorine are first removed from solution before forming the product.
description: European Chemical Bulletin, Vol 3, No 2 (2014): European Chemical Bulletin
Reply for comment on "PRODUCTION OF DICALCIUM PHOSPHATE"
Creators: name: El-Asmy, Ahmed
Publisher: name: European Chemical Bulletin
Year: 2014

description: We have been concerned with a method which is applicable in commercial scale. CaHPO4 was produced by precipitating a fraction of P2O5 using calcium carbonate (not any other calcium salt) in order to achieve the precipitation reaction in a pH below the pH of uranium and fluoride precipitation range. Finally we adjusted the pH of the final product and the ratio between Ca and P. Therefore, the final product is not contaminated with uranium.
description: European Chemical Bulletin, Vol 3, No 2 (2014): European Chemical Bulletin
Mapping Noise Pollution Using Modelled and Crowdsourced Urban Noise Data
Creators: name: Schori, Allan
name: de Róiste, Mairead
name: Schindler, Mirjam
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2025
Subjects: classificationCode: 4406
subject: Human geography
classificationCode: 3709
subject: Physical geography and environmental geoscience

description: Transport-generated noise pollution significantly burdens population health. Quantifying noise distribution and identifying areas with elevated noise levels is crucial for designing effective policy measures. We apply the CNOSSOS-EU numerical trans-port noise model to Pōneke Wellington, mapping traffic-induced noise exposure with good spatial coverage from public data. Crowdsourced noise data (CND) maps all noise sources and we spatially compare results. While unsuitable as a standalone method, CND highlights the impact of missing noise sources and offers a limited but promising validation tool for modelled data when alternatives are lacking.
M2 macrophage infusion ameliorates diabetic glomerulopathy via the JAK2/STAT3 pathway in db/db mice
Creators: name: Gu, Yulin
name: Yu, Songyan
name: Gu, Weijun
name: Li, Bing
name: Xue, Jing
name: Liu, Jiejie
name: Zhang, Qi
name: Yin, Yaqi
name: Zhang, Haixia
name: Guo, Qinghua
name: Yuan, Mingxia
name: Lyu, Zhaohui
name: Mu, Yiming
name: Cheng, Yu
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Objectives: To explore the therapeutic effects of M2 macrophages in diabetic nephropathy (DN) and their mechanism.Methods: We infused M2 macrophages stimulated with IL-4 into 10-week-old db/db mice once a week for 4 weeks through the tail vein as M2 group. Then we investigated the role of M2 macrophages in alleviating the infammation of DN and explored the mechanism.Results: M2 macrophages hindered the progression of DN, reduced the levels of IL-1β (DN group was 34%, M2 group was 13%, p < 0.01) and MCP-1 (DN group was 49%, M2 group was 16%, p < 0.01) in the glomeruli. It was also proven that M2 macrophages alleviate mesangial cell injury caused by a high glucose environment. M2 macrophage tracking showed that the infused M2 macrophages migrated to the kidney, and the number of M2 macrophages in the kidney reached a maximum on day 3. Moreover, the ratio of M2 to M1 macrophages was 2.3 in the M2 infusion group, while 0.4 in the DN group (p < 0.01). Mechanistically, M2 macrophages downregulated Janus kinase (JAK) 2 and signal transducer and activator of transcription (STAT) 3 in mesangial cells.Conclusions: Multiple infusions of M2 macrophages significantly alleviated inflammation in the kidney and hindered the progression of DN at least partially by abrogating the M1/M2 homeostasis disturbances and suppressing the JAK2/STAT3 pathway in glomerular mesangial cells. M2 macrophage infusion may be a new therapeutic strategy for DN treatment.
Additional file 1 of Cultural factors influencing COVID-19-related perceptions and behavior, seen from immigrants’ own perspective – a qualitative study in Norway
Creators: name: Vederhus, Solveig
name: Myhre, Eirik
name: Diaz, Esperanza
name: Kvalvik, Liv Grimstvedt
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Supplementary Material 1