cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Comment on 'Molecular simulation and continuum mechanics study of simple fluids in nonisothermal planar Couette flows' [J. Chem. Phys. [07], 2589 (1997)]
Creators: name: Todd, Billy
name: Evans, Denis J.
name: Travis, Karl
name: Daivis, Peter J.
Publisher: name: Swinburne
Year: 2024

description: We comment on the paper by Khare et al. [J. Chem. Phys. 107, 2589 (1997)], which considers simulations of confined fluids under planar shear with and without the application of a thermostat. We suggest an alternative interpretation of some of their results, which leads to the same conclusion that applying a thermostat directly to a confined shearing fluid is not the preferred simulation procedure to follow.
Case reports: novel TUBG1 mutations with milder neurodevelopmental presentations
Creators: name: Yuen, Yue T K
name: Guella, Ilaria
name: Roland, Elke
name: Sargent, Michael
name: Boelman, Cyrus
Publisher: name: BioMed Central
Year: 2019

description: Background: Tubulinopathies result from mutations in tubulin genes, including TUBG1, responsible for cell microtubules, are characterized by brain development abnormalities, microcephaly, early-onset epilepsy, and motor impairment. Only eleven patients with TUBG1 mutations have been previously described in literature to our knowledge. Here we present two new patients with novel de novo TUBG1 mutations and review other cases in the literature. Case presentations: Both patients have microcephaly and intellectual disability. Patient B further fits a more typical presentation, with well-controlled epilepsy and mild hypertonia, whereas Patient A’s presentation is much milder without these other features. Conclusion: This report expands the spectrum of TUBG1 mutation manifestations, suggesting the possibility of less severe phenotypes for patients and families, and influencing genetic counselling strategies.
Bone Mineral Density, Body Composition, and Metabolic Health of Very Low Birth Weight Infants Fed in Hospital Following Current Macronutrient Recommendations during the First 3 Years of Life
Creators: name: Mihatsch, Walter
name: Dorronsoro Martín, Izaskun
name: Barrios-Sabador, Vicente
name: Couce, María L.
name: Martos-Moreno, Gabriel Á.
name: Argente, Jesús
name: Quero, José
name: Saenz De Pipaon, Miguel
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: body composition
subject: dual-energy X-ray absorptiometry
subject: outcome
subject: preterm infant
subject: DDC 610 / Medicine & health
subject: Bone density
subject: Infant, Premature
subject: Infant, Very low birth weight
subject: Absorptiometry, Photon
subject: Frühgeborenes
subject: Knochendichte
subject: Dual-Röntgen-Absorptiometrie

description: The present study longitudinally evaluated growth, bone mineral density, body composition, and metabolic health outcome in very low birth weight (VLBW) infants whose in-hospital target nutrient intake was within recent recommendations. From six months to three years, bone mineral density (dual-energy X-ray absorptiometry, DXA), body composition, and metabolic health outcome were compared with a reference group of term infants. The aim was to test whether in-hospital achieved weight gain until 36 weeks of gestation (light or appropriate for term equivalent age; LTEA or ATEA) predicts later growth, bone mineral density (BMD), abdominal obesity, or metabolic health outcomes such as insulin resistance, relative to term infants, during the first three years of life. Target in-hospital energy and protein intake was not achieved. Growth in weight, length and head circumference, mid arm circumference, adiposity, fat free mass (FFM), and bone mineralization in VLBW infants was less than those in term infants and influenced by nutritional status at discharge. Preterm infants had poorer motor and cognitive outcomes. Post-discharge body composition patterns indicate FFM proportional to height but lower fat mass index in LTEA preterm infants than term infants, with no evidence of increased truncal fat in preterm infants. The hypothesis of early BMD catch-up in VLBW infants after discharge was not supported by the present data. The clinical significance of these findings is unclear. The data may suggest a reduced obesity risk but an increased osteoporosis risk. Since postnatal growth restriction may have permanent negative health effects, LTEA VLBW infants would especially appear to benefit from targeted preventive interventions. Further follow-up of the infants is required.
Surgical Stress Attenuates Pre-existing Anti-tumour Immunity Resulting in Postoperative Metastases and local Recurrence in a Murine Model
Creators: name: Ananth, Abhirami
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: subject: Cancer
subject: Immunology
subject: FOS: Clinical medicine
subject: Surgery
subject: T-cells
subject: Surgical stress
subject: Vaccines

description: Solid malignancies in cancer patients require surgical intervention; however, surgery has been shown to promote the metastatic potential of tumour cells. Surgery-induced impairment of adaptive immunity is poorly understood, thus, our aim is to characterize the impact of surgery on tumour antigen-specific cytotoxic T lymphocyte function. To generate anti-tumour immunity, we adopted a C57/B6 model of B16 melanoma immunized with intramuscular (IM) AdhDCT, an adenovirus expressing the melanoma-associated antigen human dopachrome tautomerase (hDCT). Surgical stress was induced by left abdominal nephrectomy. We found that surgery reduces overall survival in AdhDCT-immunized mice, whereas those that did not undergo surgery were cured of their tumours. Surgical stress also decreases both the proportion and absolute spleen numbers of DCT-specific IFN-gamma+ CD8+ T-cells by over 2-fold. We have shown that perioperative suppression of antigen-specific T-cells can lead to increased tumour burden in a murine melanoma model.
The Crisis of the Social Realist Novel in the United States: The "Tragic" Case of Jonathan Franzen's Strong Motion
Creators: name: Porro, Simona
Publisher: name: Iperstoria
Year: 2019
Subjects: Jonathan Franzen; Socialist Realist Novel

description: Jonathan Franzen’s production is characterized by a body of non-fiction writing that has greatly contributed to the heated debate about the declining relevance of the novel in contemporary America. In his controversial essay “Perchance to Dream: In the Age of Images, a Reason to Write Novels,” published in 1996, Franzen acknowledged the diminished cultural role of highbrow novels in a nation dominated by consumerism, mass culture, new media and instant entertainment. In this light, the author made a public call for ambitious fiction to rise to the challenges of the late twentieth century. Interestingly, Franzen equated such novels with the “tragic” mode: by “tragic” he meant “just about any fiction that raises more questions than it answers: anything in which conflict doesn’t resolve into cant.” Much of Franzen’s fiction participates in the same discourse that is developed in his essayistic production, especially his early work, which is infused with large-scale social and cultural critique. His second novel in particular, Strong Motion, having been completed in the early 1990s, at the height of his frustration with the coeval American novel, appears of particular interest. Strong Motion exposes what Franzen aptly calls “the dirt” behind the American “dream of Chosenness.” The novel decries the failure of a nation that, far from being a shining “City upon a Hill,” has fallen prey to an unstoppable process of cultural and moral entropy that coincided with the inception of a “predatory” capitalistic system of power, which has influenced gender and social roles, the notion of progress, and the general attitude to the natural world, with the environment in particular being brutally degraded to mere infrastructure. In so doing, the book stands as an example of the author’s “tragic” mode.
description: Iperstoria, No 13 (2019): Negotiating Meaning in Business English as a Lingua Franca
MPEC 2025-E61 : 2025 EO
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 EO

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Pythagoras Unchained
Creators: name: Brown, Adam
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2014
Subjects: social practice
visual art
participation
interaction
political art

description: Recounts the author’s trajectory in the Masters of Fine Arts program. Describes the nature of his early practice in interactive sound art and its later development into sculptural, performative and social forms. Key theoretical influences in this development are identified and discussed in detail. In particular the writings of the philosopher Jacques Rancière and cricic Claire Bishop are discussed, as well as the work of artists William Pope.L, Joar Nango and Thomas Hirschhorn.
Haemopedia: An Expression Atlas of Murine Hematopoietic Cells
Creators: name: de Graaf, Carolyn A.
name: Choi, Jarny
name: Baldwin, Tracey M.
name: Bolden, Jessica
name: Fairfax, Kirsten A.
name: Robinson, Aaron J.
name: Biben, Christine
name: Morgan, Clare
name: Ramsay, Kerry
name: Ng, Ashley P.
name: Kauppi, Maria
name: Kruse, Elizabeth A.
name: Sargeant, Tobias J.
name: Seidenman, Nick
name: D'Amico, Angela
name: D'Ombrain, Marthe C.
name: Lucas, Erin C.
name: Koernig, Sandra
name: Baz Morelli, Adriana
name: Wilson, Michael J.
name: Dower, Steven K.
name: Williams, Brenda
name: Heazlewood, Shen Y.
name: Hu, Yifang
name: Nilsson, Susan K.
name: Wu, Li
name: Smyth, Gordon K.
name: Alexander, Warren S.
name: Hilton, Douglas J.
Publisher: name: Swinburne
Year: 2024

description: Hematopoiesis is a multistage process involving the differentiation of stem and progenitor cells into distinct mature cell lineages. Here we present Haemopedia, an atlas of murine gene-expression data containing 54 hematopoietic cell types, covering all the mature lineages in hematopoiesis. We include rare cell populations such as eosinophils, mast cells, basophils, and megakaryocytes, and a broad collection of progenitor and stem cells. We show that lineage branching and maturation during hematopoiesis can be reconstructed using the expression patterns of small sets of genes. We also have identified genes with enriched expression in each of the mature blood cell lineages, many of which show conserved lineage-enriched expression in human hematopoiesis. We have created an online web portal called Haemosphere to make analyses of Haemopedia and other blood cell transcriptional datasets easier. This resource provides simple tools to interrogate gene-expression-based relationships between hematopoietic cell types and genes of interest.
Análisis económico de la contratación estatal
Creators: name: Safar Díaz, Mónica Sofía
Publisher: name: Universidad Externado de Colombia
Year: 2010
Subjects: subject: Contratos públicos - Congresos, conferencias, etc
subject: Administración pública - Congresos, conferencias, etc
subject: Funcionarios públicos - Congresos, conferencias, etc

description: La contratación estatal ha sufrido recientemente grandes modificaciones, en especial en lo concerniente a los procedimientos de selección de contratistas del Estado, el régimen de garantías contractuales y la regulación sobre los riesgos inherentes a la actividad contractual, de forma paralela a la consagración legal de tendencias jurisprudenciales decantadas durante años respecto de ciertos vacíos de la legislación anterior. No obstante, se observa que esta nueva normatividad contenida en la Ley 1150 de 2007 se ha constituido principalmente en complementaria de la Ley 80 de 1993, toda vez que esta última no fue derogada en su totalidad, de tal manera que los principios tradicionales de transparencia, economía, responsabilidad, buena fe, igualdad, interpretación y modificación y equilibrio económico continúan vigentes.
Is there an association between hospital occupancy and quality of care?
Creators: name: Forster, Alan John.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Health Sciences, Medicine and Surgery.

description: Statement of the problem. Hospital occupancy is the number of inpatients divided by the number of beds. It has risen over the last two decades in many countries. This thesis will determine if there is an association between hospital occupancy and quality of care. Setting. The Ottawa Hospital - Civic Campus, a tertiary care teaching hospital in Ottawa, Canada between January 1, 1993 and July 31, 1999. Methods. Daily rates of hospital occupancy and several quality of care indicators were derived using administrative databases. Indicators included: efficiency outcomes (emergency room (ER) delay, hospital length of stay (LOS), off service transfers, bed to bed transfers, and operating room (OR) cancellations); inpatient outcomes (deaths, cardiac arrests, c. difficile infections, medication errors, and falls); and outpatient outcomes (7- and 30-day visits to any ER, urgent readmissions to any hospital, and deaths). Autoregressive Integrated Moving Average (ARIMA) time-series modeling was used to test the association between hospital occupancy and each of the outcomes. Results. Significant, positive associations were identified between daily occupancy rates and the following outcomes: ER delay, off service transfer, bed to bed transfers, and the proportion of patients dying within 30 days of discharge. Significant negative associations were identified between occupancy and length of stay and hospital deaths. Conclusion. This study demonstrates that quality of care is associated with hospital occupancy. Further research is required to validate the clinical importance of the efficiency indicators used and to adjust occupancy for case-mix.
Automating handover in dynamic workflow environments
Creators: name: Liu, Chengfei
name: Orlowska, Maria E.
name: Li, Hui
Publisher: name: Swinburne
Year: 2024

description: Workflow technology has been widely used in business process modelling, automation and reengineering. In order to meet the fast-changing business requirements, to remain competitive in the market, an enterprise may constantly refine the workflow models of its business processes. The most challenging issue in evolution of a workflow model is the handover of its running instances from the old specification to the new specification. Such a handover depends on the semantics of a workflow model as well as the execution information of its running instances. A handover policy, therefore, needs to be specified for this purpose. In this paper, we propose a simple yet effective handover policy specification language. Using this language, a designer can easily specify a handover policy which reflect exactly what a workflow administrator needs to react to when a workflow model evolves. Criteria for the correct specification of handover policies are also addressed. Finally, a framework for automating handover of workflow instances is presented.
Visibility and Obscurity Within the Surveillance Regime of the U.S. Prison
Creators: name: Schrag, David
Publisher: name: Iperstoria
Year: 2020

description: Prisons are physical and imagined objects of fascination. Dramatic images of prison life are highly available in the public imaginary, yet the lives of typical prisoners remain obscure from public view. Through media portrayals—both fictional and ‘real’—the public is led to visualize the prison primarily in terms of dramatic physical violence. At a different level of public visibility, the external physical features of the prison facilities themselves project a message of violence (e.g. through razor-wire fences and gun towers) and thus an implicit message about the publicly-unseen population secluded within its walls. This essay examines issues of visibility and obscurity in regard to the present-day “control prison” (Rhodes 2004)—a regime that functions primarily as a means of punitive social exclusion. Kleinman’s (1997) anthropological concepts of social violence and social suffering will be used to discuss the diffuse, less-readily-visible, forms of violence which are the product of the social separation created by the prison regime, and help us to more critically engage with representations of the prison.
description: Iperstoria, No 14 (2019): The USA as Penitentiary
Event-related potentials and behavioural responses associated with a loss of consciousness at sleep onset.
Creators: name: De Lugt, Duncan R.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1997
Subjects: subject: Psychology, Psychobiology.

description: This thesis examined changes in the brain's responses ("evoked potentials") during the transition from consciousness to unconsciousness. A negative wave, "N1", peaking at about 100 ms is affected by the subject's extent of attention/consciousness. Unfortunately, this same peak is also affected by manipulation of the physical parameters of the stimulus. The extent to which a component is affected by a physical or psychological parameter is often difficult to determine in the awake and alert subject. There are two principal reasons for this. Manipulation of the physical stimulus may inadvertently cause a change in the psychological state of the subject. Thus, subjects will attend to louder stimuli even if not asked to do so. Manipulation of the subject's level of attention also poses a dilemma. The change in the level of attention is always relative, not absolute. When subjects are asked to ignore stimuli, they are not able to do so. The sleep period provides a convenient means to resolve this dilemma. It is the period of time during which subjects are least attentive to, and thus least conscious of, their external environment. It can therefore be used to provide a baseline-near absolute level of attentiveness. Three experiments were run. In the first experiment, tones were presented to subjects at a rapid 600 ms interstimulus interval, during sleep onset (the transition period from Wakefulness through to Stage 2 of sleep). Subjects were not required to respond to the stimuli. In Experiment 2 stimuli were presented at a relatively slow rate (every 1000 msi. Again, subjects were not required to make an overt response. In Experiment 3 spatial resolution was enhanced by recording from 29 scalp electrode sites. Topographic changes to the P1-N1-P2 evoked potential complex during sleep onset were investigated. In addition, several novel methodological changes were implemented in this final study. Stimuli were presented in an oddball paradigm. Rare "target" tones were randomly presented within a train of frequently occurring standard stimuli. Subjects were required to press a hand held button whenever they detected a target stimulus. A radical interpretation of the present data is that a late negative wave, "N1", is entirely endogenous in nature. N1 may reflect the extent of the subject's conscious awareness of the external stimulus. As such, the N1 component of the auditory evoked potential provides a convenient and easy means to monitor the level of attention/consciousness in a number of applied settings. (Abstract shortened by UMI.)
Many Kinds of Prison: Charles Dickens on American Incarceration and Slavery
Creators: name: Archibald, Diana C.
Publisher: name: Iperstoria
Year: 2020

description: When the famous British novelist Charles Dickens arrived in North America in 1842, he came at an ideal time to examine the effects of the first wave of penal reform and prison building. His eye-witness account offers valuable insight into American incarceration practices. Taking a stand on the debate over what form incarceration ought to take, Dickens lands squarely in the camp of those supporting the Congregate or Auburn System, a type of penitentiary that allowed inmates to be with each other by day, performing work silently but in proximity to other human beings. Dickens opposed the misguided Separate or Pennsylvania System which enforced utter isolation through almost perpetual solitary confinement. Dickens not only exposes the cruelty of this system but he illuminates the cruelty of American slavery, yet another form of imprisonment. Most importantly, Dickens exposes the special brand of hypocrisy born of American exceptionalism that he discovers on his trip and lambasts the young republic for its blind boasts about ideals Dickens thought were not being upheld: Freedom and Justice. Dickens’s travel book, American Notes, contains markers that point toward the 20th- and 21st-century future of mass incarceration, and his powerful literary journalism is still relevant today.
description: Iperstoria, No 14 (2019): The USA as Penitentiary
Opportunities and limits of recycling in the context of the circular economy
Creators: name: Hagelüken, Christian
name: Schmidt, Mario
name: Schebek, Liselotte
Publisher: name: German Environment Agency
Year: 2023
Subjects: subject: Kreislaufwirtschaft
subject: Ressourcennutzung
subject: Rohstoffbedarf
subject: Recycling
subject: circular economy
subject: resource use
subject: demand for raw materials
subject: Waste | Resources

description: In addition to environmental and climate policy objectives, the Circular Economy is also essential for strengthening the security of supply and for achieving further economic and socio-economic goals. Recycling is one of the key factors along with a range of other approaches and strategies (e.g., longevity, Intensity of use, and the sharing economy). In order to assess the contribution and the limits of recycling for sustainable resource use and climate protection, there is a need for a clear definition of the assessment framework and system boundaries, as well as for precisely formulated calculation approaches and indicators. In this paper, the Resource Commission at the German Environment Agency (KRU) summarizes the current state of knowledge on recycling and recommends possible indicators with a focus on metals, which play a key role in the energy transition and for climate protection. Quelle: umweltbundesamt.de
description: In addition to environmental and climate policy objectives, the Circular Economy is also essential for strengthening the security of supply and for achieving further economic and socio-economic goals. Recycling is one of the key factors along with a range of other approaches and strategies (e.g., longevity, Intensity of use, and the sharing economy). In order to assess the contribution and the limits of recycling for sustainable resource use and climate protection, there is a need for a clear definition of the assessment framework and system boundaries, as well as for precisely formulated calculation approaches and indicators. In this paper, the Resource Commission at the German Environment Agency (KRU) summarizes the current state of knowledge on recycling and recommends possible indicators with a focus on metals, which play a key role in the energy transition and for climate protection.
Los discursos de las negociaciones de paz de La Habana 2012-2016
Creators: name: Cabrera Parrado, Luis Miguel
Publisher: name: Universidad Externado de Colombia
Year: 2016
Subjects: subject: Cultura de paz - Aspectos sociales
subject: Acuerdos de paz - Condiciones sociales
subject: Guerrillas - Colombia
subject: Proceso de paz
subject: Las FARC
subject: Análisis crítico del discurso
subject: Discurso político
subject: Conflicto armado

description: El objetivo de este trabajo es realizar un análisis crítico del discurso de los jefes negociadores de las FARC y el gobierno de Colombia durante el proceso de negociación del Acuerdo Final para la Terminación del Conflicto y la Construcción de una Paz Estable y Duradera. Este trabajo se propone revisar los discursos que conformaron el inicio y la finalización de la segunda fase del proceso de paz para identificar si existen variaciones entre ellos, si se manifiesta la presencia de un trasfondo histórico y poder establecer la intencionalidad y la posición de ambos actores, principalmente en términos ideológicos. Se concluye que ambos discursos han variado, que existe evidencia de un trasfondo histórico que en el caso de las FARC es más amplio y se hace presente una estructura de polarización que en el caso de las FARC busca deslegitimar al Estado y legitimarse a sí mismo. Por otro lado, el discurso de Humberto De la Calle busca principalmente dar legitimidad al proceso, a las acciones del gobierno y a su gestión y deslegitimar el accionar de la oposición.
description: The aim of this study is to make a critical analysis of the discourse of the negotiating delegates of FARC and the government of Colombia during the negotiation process of the Final Agreement. This paper intends to review the speeches that formed the beginning and the end of the second phase of the peace process in order to identify if there are variations between them, to determine the presence of a historical background and to establish the intentionality and the position of both actors, mainly in ideological terms. The conclusion is that both discourses have changed, there is evidence of a historical background that in the case of FARC is broader, a structure of polarization is present, in the case of FARC this structure tends to delegitimize the state and to legitimize themselves. In the government’s delegate case it seeks to give legitimacy to the process, to the government and to his duty as government’s chief negotiator. It also tends to delegitimize the actions of the opposition.
Biopower is the New Black: Gender Refractions and Reflections Between Panopticon and Television
Creators: name: Ferrante, Antonia Anna
Publisher: name: Iperstoria
Year: 2020

description: What can be visible of a queer body behind the bars? I will try to answer this question through the critical analysis of Orange is the New Black, a TV series produced by Netflix and based on Piper Kerman’s autobiographical novel. Imprisoned queer bodies are at the center of my analysis. Prison is the paradigm of the system of surveillance and confinement of bodies. Queer bodies are themselves a site of the exercise of power. In prison, gender non- conforming bodies are subjected to the consuetudinary discipline of sexuality and to arbitrary forms of discipline and punishment, such as the re-assignation to a non-desired gender, the duty of conforming to it, the administration of hormones, and a systematic exercise of violence. I am allowed to see behind the bars through the lens of a fictional representation in a TV show. Despite the stereotypical representation of its characters, the show explores the tension between the inmates’ desire of the inmates to escape the cage of heteronormativity and biopower' s desire (and need) for discipline. My critical reading will be framed in Angela Davis' s analysis on how gender structures prison (Davis, 2003). I will try to go further and understand how prison is a gendered institution, since gender and heteronormativity are themselves systems of surveillance and discipline (Stanley and Smith, 2011). Prison shapes bodies and disciplines gender, as well as gender informs and structures prison. The screen offers yet another and more complex perspective, acting as a lens through which we can watch the Panopticon. Discipline impacts not only on gender politics, but also on the regime of visibility for queer subjects. I want to focus on how the show stages the interplay of refractions between what can be visible and tolerable in prison and what can be tolerable and visible in the society (Foucault, 1975).
description: Iperstoria, No 14 (2019): The USA as Penitentiary
Who says “no” to participating in stroke clinical trials and why: an observational study from the Vancouver Stroke Program
Creators: name: O’Neill, Zoe R
name: Deptuck, Halina M
name: Quong, Lauren
name: Maclean, Genoveva
name: Villaluna, Karina
name: King-Azote, Princess
name: Sharma, Mukul
name: Butcher, Ken
name: Hart, Robert G
name: Field, Thalia S
Publisher: name: BioMed Central
Year: 2019

description: Background: Successful stroke trials require adequate recruitment. In this observational study, we assessed reasons for refusal to provide informed consent in eligible patients approached for clinical trial participation at the Vancouver Stroke Program. Methods: We assessed screening logs from four trials that were actively recruiting at our center: three randomized trials, two of which investigated different antithrombotic strategies for secondary prevention (NAVIGATE-ESUS, NCT02313909 12/2014; DATAS-II, NCT02295826 11/2014) and one that investigated surgery plus medical management versus medical management alone for primary prevention (CREST-2, NCT02089217 03/2014). The fourth study was observational and non-randomized; all participants received an external monitoring device (PROPHECY, NCT03712865 10/2018). Screening logs from June 2015 to April 2017 were reviewed retrospectively. Subsequently, we used a prospective structured case report form for screening (May 2017–March 2018). We assessed and compared refusal rates between trials, demographics of those refusing consent, and their reasons for doing so. We used descriptive statistics, chi-square and Fisher’s exact tests as appropriate for non-parametric data, and t-tests for parametric data. We examined likelihood of refusal by sex using multivariable logistic regression models including age and trial intervention as co-variables. Results: A total of 235 patients (43% women) were approached for consent. More patients refused the surgical (59%) and antithrombotic trials (53%) compared with the non-randomized external monitoring device study (13%) (p < 0.001). Surgical trial refusals were primarily due to a desire for certainty in receiving a particular intervention (39%), with the majority of those patients wanting surgery. Refusals for the antithrombotic trials were mainly due to concerns with the potential side effects of the study drug (41%); refusals in the device trial were mainly due to disinterest (46%). Women refused participation more often than men (48% vs 33%). Women remained less likely to consent than men, even after adjustment for age and trial intervention (OR 0.46, 95% CI 0.26–0.82, p = 0.009). Conclusions: Concern surrounding drug safety, randomization, and disinterest were the chief deterrents to enrolment; there were also differences in rates of consent by gender. A better understanding of why patients refuse participation in stroke trials may help to develop future patient-directed communication strategies to improve enrolment. Further research is required to better understand the reasons underlying gender disparities in consent rates.
Translating Boundaries: Constraints, Limits, Opportunities. A cura di Stefanie Barschdorf e Dora Renna
Creators: name: Taronna, Annarita
Publisher: name: Iperstoria
Year: 2020
Subjects: Translation Studies

description: Review of Translating Boundaries: Constraints, Limits, Opportunities. Ed. by Stefanie Barschdorf and Dora Renna
description: Iperstoria, No 14 (2019): The USA as Penitentiary
The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency
Creators: name: Lu, Weisi
name: Yu, Jianping
name: Shi, Fengtao
name: Zhang, Jianing
name: Huang, Rui
name: Yin, Shanshan
name: Songyang, Zhou
name: Huang, Junjiu
Publisher: name: BioMed Central
Year: 2019

description: Background: Small nucleolar RNA host gene 3 (Snhg3) is a long non-coding RNA (lncRNA) that was shown to participate in the tumorigenesis of certain cancers. However, little is known about its role in embryonic stem cells (ESCs). Methods: Here, we investigated the role of Snhg3 in mouse ESCs (mESCs) through both loss-of-function (knockdown) and gain-of-function (overexpression) approaches. Alkaline phosphatase staining, secondary colony formation, propidium iodide staining, western blotting, and quantitative reverse transcription polymerase chain reaction (qRT-PCR) were used to access self-renewal capacity, whereas immunofluorescence, qRT-PCR, and embryoid body formation were performed to examine pluripotency. In addition, the effect of Snhg3 on mouse embryonic development was determined based on the morphological changes, blastocyst rate, and altered pluripotency marker (Nanog, Oct4) expression. Moreover, the relationship between Snhg3 and key pluripotency factors was evaluated by chromatin immunoprecipitation qPCR, qRT-PCR, subcellular fractionation, and RNA immunoprecipitation. Finally, RNA pull-down and mass spectrometry were applied to explore the potential interacting proteins of Snhg3 in mESCs. Results: We demonstrated that Snhg3 is essential for self-renewal and pluripotency maintenance in mESCs. In addition, Snhg3 knockdown disrupted mouse early embryo development. Mechanistically, Snhg3 formed a positive feedback network with Nanog and Oct4, and 126 Snhg3-interacting proteins were identified in mESCs. Conclusions: Snhg3 is essential for mESC self-renewal and pluripotency, as well as mouse early embryo development.
title: UN DRÔLE DE DIMANCHE
Creators: name: Misraki, Paul
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2025
Subjects: subject: Musique de film

description: Manuscrits des partitions musicales du film réalisé par Marc Allégret : UN DRÔLE DE DIMANCHE. 103 grandes pages, 3 A4
description: Temporal: XXème siècle
Los rasgos del discurso populista en el discurso de Cristina Fernández de Kirchner
Creators: name: Arias Urrego, Estrella
Publisher: name: Universidad Externado de Colombia
Year: 2017
Subjects: subject: Historia moderna - Siglo XX
subject: Economía - Aspectos sociales
subject: Medios de comunicación de masas - Aspectos políticos
subject: Cristina Fernández
subject: Análisis de discurso
subject: Populismo
subject: Neopopulismo
subject: Patrick Charadeau

description: La presente investigación busca dar a conocer los rasgos del discurso populista de Cristina Fernández de Kirchner, cuando ejercicio sus funciones como presidente de Argentina. En este trabajo se explica paso a paso que es el populismo, neopopulismo, análisis de discurso, entre otros ejes temáticos que fueron de gran importancia para llevar a cabo la ejecución de la investigación propuesta. También se encuentra la importancia que tuvo la llegada de los Kirchner al poder, la crisis que vivió Argentina por los malos gobiernos que tuvo el país, no se puede decir que bajo su mandato todo fue perfecto, pero sí se logró sanear un poco la situación económica, social y política. Aquí se puede encontrar un poco sobre la historia contemporánea de Argentina, como era un poco el manejo de los medios de comunicación respecto a los gobernantes de turno, como los argentinos lograron confiar nuevamente en los políticos debido al cambio que estos le dieron al país.
description: The present investigation seeks to publicize the features of the populist discourse of Cristina Fernández de Kirchner, when she exercises her functions as president of Argentina. In this work we explain step by step what is populism, neopopulism, discourse analysis, among other thematic axes that were of great importance to carry out the execution of the proposed research. There is also the importance of the arrival of the Kirchners to power, the crisis that Argentina experienced due to the bad governments that the country had, it can not be said that under its mandate everything was perfect, but it was able to remedy the situation a bit economic, social and political. Here you can find a bit about the contemporary history of Argentina, as it was a bit the management of the media with respect to the current rulers, as the Argentines managed to trust politicians again dueto the change they gave to the country.
All options, not silver bullets, needed to limit global warming to 1.5 ˚C: a scenario appraisal
Creators: name: Klingenfeld, Daniel
name: Warszawski, Lila
name: Kriegler, Elmar
name: Lenton, Timothy M.
name: Messner, Dirk
Publisher: name: My University
Year: 2021
Subjects: Klimaänderung

description: Climate science provides strong evidence of the necessity of limiting global warming to 1.5 ˚C, in line with the Paris Climate Agreement. The IPCC 1.5 ˚C special report (SR1.5) presents 414 emissions scenarios modelled for the report, of which around 50 are classified as '1.5 ˚C scenarios', with no or low temperature overshoot. These emission scenarios differ in their reliance on individual mitigation levers, including reduction of global energy demand, decarbonisation of energy production, development of land-management systems, and the pace and scale of deploying carbon dioxide removal (CDR) technologies. The reliance of 1.5 ˚C scenarios on these levers needs to be critically assessed in light of the potentials of the relevant technologies and roll-out plans. We use a set of five parameters to bundle and characterise the mitigation levers employed in the SR1.5 1.5 ˚C scenarios. For each of these levers, we draw on the literature to define 'medium' and 'high' upper bounds that delineate between their 'reasonable', 'challenging' and 'speculative' use by mid century. We do not find any 1.5 ˚C scenarios that stay within all medium upper bounds on the five mitigation levers. Scenarios most frequently 'over use' CDR with geological storage as a mitigation lever, whilst reductions of energy demand and carbon intensity of energy production are 'over used' less frequently. If we allow mitigation levers to be employed up to our high upper bounds, we are left with 22 of the SR1.5 1.5 ˚C scenarios with no or low overshoot. The scenarios that fulfil these criteria are characterised by greater coverage of the available mitigation levers than those scenarios that exceed at least one of the high upper bounds. When excluding the two scenarios that exceed the SR1.5 carbon budget for limiting global warming to 1.5 ˚C, this subset of 1.5 ˚C scenarios shows a range of 15-22 Gt CO2 (16-22 Gt CO2 interquartile range) for emissions in 2030. For the year of reaching net zero CO2 emissions the range is 2039-2061 (2049-2057 interquartile range). © 2021 The Author(s).
The technology gap and the emergence of French and German industrial policy in the domain of data processing and computers, 1960--1970
Creators: name: Picher, Andrea
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: History, European.
subject: History, Modern.

description: The idea that a technology gap between the United States of America and Western Europe existed emerged in the early 1960s. Western Europeans attributed the gap to a dramatic increase in direct American investment, government support for R and D, firm size, as well as the brain drain, while American Scholars argued that the roots of the gap were the archaic educational systems and the hierarchical social structures of Western Europe. In order to support their national computer industries against American competition, French and German policy makers chose to counter the technology gap by developing national support programs. Although both countries responded to the same socio-economic problem, the resulting industrial programs differed fundamentally. The purpose of this study is to gain an understanding of industrial policy in the 1960s and, through a comparative analysis show, how industrial policy is shaped by political and cultural aspects within individual countries.
Contratación pública y corrupción
Creators: name: Safar Díaz, Mónica Sofía
Publisher: name: Universidad Externado de Colombia
Year: 2018
Subjects: subject: Corrupción - Colombia
subject: Corrupción administrativa – Colombia
subject: Delitos contra la administración pública - Colombia
subject: Contrato estatal
subject: Corrupción
subject: Agencia
subject: Incentivos
subject: Asimetría de información
subject: Planeación

description: La contratación estatal es un mecanismo de intercambio de bienes y servicios en el marco de un mercado en el cual el Estado se comporta generalmente como consumidor; desde el punto de vista de la oferta y la demanda, la realidad demuestra la existencia de un contexto muy complejo que detona la configuración de muchas de esas conductas catalogadas como actos de corrupción. Pero, ¿en el entorno de la contratación pública en Colombia, y en el marco de la transparencia, son realmente aplicables las premisas mundialmente adoptadas como actos de lucha contra la corrupción?, ¿o debemos empezar por enfocarnos en el problema inmediato de la necesidad de que se realicen las obras, bienes y servicios que necesita el Estado para cumplir con sus deberes constitucionales y legales, más allá del reproche a las conductas individuales? La corrupción en la contratación pública es un tema de constante debate y reiterado análisis en el mundo entero, pero en países en desarrollo, como Colombia, se propone un cambio de perspectiva con el fin de afrontar el problema desde nuestra propia realidad y contexto histórico y cultural, por lo que entender el flagelo a partir del problema de agencia, y de la asimetría de información, analizando la posición de cada uno de los partícipes permite dimensionarlo y tomar otras medidas más allá de la sancionatoria, la cual no ha resultado efectiva.
Choose life: the art of Lyndal Walker
Creators: name: Huppatz, Danny J.
Publisher: name: Swinburne
Year: 2024

description: Lyndal Walker's art is a documentary project which records contemporary taste and the forces that create, manipulate and sustain it. In her installations, Walker documents 'unimportant' things; details of style and fashion that are often overlooked, 'street' styles that help mould and in turn are co-opted by mass consumer culture. Her investigative process makes use of various reproductive technologies, appropriating the language and style of high fashion and advertising. From her early work on punk revival and grunge to her latest work on share house living, there is always a critical edge to her art that questions the dissemination of styles and the manipulation of taste in a mass media society. [Introduction]
Incarcerating Disability: How Society-Wide Structural Violence Diminishes Justice for People with Intellectual and Developmental Disabilities
Creators: name: Sarrett, Jennifer
Publisher: name: Iperstoria
Year: 2020

description: People with I/DDs such as autism, fetal alcohol syndrome, and general cognitive impairments are victimized by the criminal justice system, whether they encounter it as victims or as the accused. Although at drastically higher risk for being victimized, they are further victimized by the testimonial injustice that prevents the crimes against people with I/DD from being investigated, and so these victims rarely justice. In the aftermath of deinstitutionalization and growing economic disparity, people with I/DD are disproportionately represented in incarcerated settings. Once incarcerated, they often serve longer, harder sentences. This article provides an overview of what we know about people with I/DD in criminal justice settings and structures and what we need to learn. Based partly on preliminary qualitative research with adults with I/DD about their experiences with criminal justice settings and structures, I argue that this population is falling through the cracks in an already fragile and uneven justice system.
description: Iperstoria, No 14 (2019): The USA as Penitentiary
Electrostatic Control of Single InAs Quantum Dots Using InP Nanotemplates
Creators: name: Cheriton, Ross
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2012
Subjects: quantum dot
electrostatic
exciton
gates
nanotemplate
nanotechnology
quantum physics
nano

description: This thesis focuses on pioneering a scalable route to fabricate quantum information devices based upon single InAs/InP quantum dots emitting in the telecommunications wavelength band around 1550 nm. Using metallic gates in combination with nanotemplate, site-selective epitaxy techniques, arrays of single quantum dots are produced and electrostatically tuned with a high degree of control over the electrical and optical properties of each individual quantum dot. Using metallic gates to apply local electric fields, the number of electrons within each quantum dot can be tuned and the nature of the optical recombination process controlled. Four electrostatic gates mounted along the sides of a square-based, pyramidal nanotemplate in combination with a flat metallic gate on the back of the InP substrate allow the application of electric fields in any direction across a single quantum dot. Using lateral fields provided by the metallic gates on the sidewalls of the pyramid and a vertical electric field able to control the charge state of the quantum dot, the exchange splitting of the exciton, trion and biexciton are measured as a function of gate voltage. A quadrupole electric field configuration is predicted to symmetrize the product of electron and hole wavefunctions within the dot, producing two degenerate exciton states from the two possible optical decay pathways of the biexciton. Building upon these capabilities, the anisotropic exchange splitting between the exciton states within the biexciton cascade is shown to be reversibly tuned through zero for the first time. We show direct control over the electron and hole wavefunction symmetry, thus enabling the entanglement of emitted photon pairs in asymmetric quantum dots. Optical spectroscopy of single InAs/InP quantum dots atop pyramidal nanotemplates in magnetic fields up to 28T is used to examine the dispersion of the s, p and d shell states. The g-factor and diamagnetic shift of the exciton and charged exciton states from over thirty single quantum dots are calculated from the spectra. The g-factor shows a generally linear dependence on dot emission energy, in agreement with previous work on this subject. A positive linear correlation between diamagnetic coefficient and g-factor is observed.
Creativity in English as a Lingua Franca: Idiom and Metaphor. Marie-Luise Pitzl
Creators: name: Antonello, Monica
Publisher: name: Iperstoria
Year: 2020
Subjects: ELF; Creativity; Idiom

description: Review of Creativity in English as a Lingua Franca: Idiom and Metaphor by Marie-Luise Pitzl
description: Iperstoria, No 14 (2019): The USA as Penitentiary
Global migration and transformation among Canadian Pentecostals.
Creators: name: Wilkinson, Michael.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Religion, General.

description: Since the 1970s migration to Canada has changed from European to non European sources. What, then, are the implications of global migration for religion in Canada and specifically the Pentecostal Assemblies of Canada (PAOC)? Previous research on migrant groups has examined both pluralist and assimilationist tendencies. In this thesis incorporating both sociology of religion and ethnicity approaches, I supplement previous research by examining the transnational aspects of ethnic congregations in the PAOC. Roland Robertson (1992) argues that the current phase of globalization is characterized by uncertainty and has implications for religion. According to Robertson's theory, religion gets restructured in terms of both local and global dynamics. Thus, the effects of globalization include theological, cultural, and organization change for the PAOC. The research examined the views and practices of the members of eight different congregations (N = 430) from a variety of cultural backgrounds including, Spanish, Korean, Tamil, Eritrean and European. The results show that the PAOC and the congregations are reacting in flexible and varied ways to global migration precisely because experiential religion allows ethnicity as a strategy, networks as an organizational mode, and charisma as authority.