cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Spectral and Timing properties of the recently discovered Be/X-ray pulsar eRASSUJ 052914.9-662446
Creators: name: Rai, Binay
name: Ghising, Manoj
name: Tobrej, Mohammed
name: Tamang, Ruchi
name: Paul, Bikash Chandra
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We have presented NuSTAR and Swift observations of the newly discovered Be/X-ray pulsar eRASSU J052914.9-662446. This is the first detailed study of the temporal and spectral properties of the pulsar using 2020 observations. A coherent pulsation of 1411.5$\pm$0.5 s was detected from the source. The pulse profile was found to resemble a simple single peaked feature which may be due to emission from the surface of the neutron star only. Pulse profiles are highly energy dependent. The variation of the pulse fraction of the pulse profiles are found to be non-monotonic with energy. The 0.5-20 keV Swift and NuSTAR simultaneous can be fitted well with power-law modified by high energy cutoff of $\sim$ 5.7 keV. The NuSTAR luminosity in the 0.5-79 keV energy range was $\sim$ 7.9x10 35 erg/s. The spectral flux in 3-79 keV shows modulation with the pulse phase.
description: Accepted for publication in MNRAS
Epoxyeicosanoids promote organ and tissue regeneration
Creators: name: Jenkins, R. L.
name: Le, H. D.
name: Mammoto, T.
name: Butterfield, C. E.
name: Kieran, M. W.
name: Manthati, V. L.
name: Falck, J. R.
name: Tomer, K. B.
name: Mudge, D. K.
name: Zeldin, D. C.
name: Yang, J.
name: Ingber, D. E.
name: Lih, F. B.
name: Puder, M.
name: Benny, O.
name: Hammock, B. D.
name: Bielenberg, D. R.
name: Lee, C. R.
name: Kaipainen, A.
name: Kalish, B. T.
name: Huang, S.
name: Simpson, M. A.
name: Panigrahy, D.
name: D'Amore, P. A.
name: Edin, M. L.
name: Akino, T.
name: Inceoglu, B.
name: Mammoto, A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Epoxyeicosatrienoic acids (EETs), lipid mediators produced by cytochrome P450 epoxygenases, regulate inflammation, angiogenesis, and vascular tone. Despite pleiotropic effects on cells, the role of these epoxyeicosanoids in normal organ and tissue regeneration remains unknown. EETs are produced predominantly in the endothelium. Normal organ and tissue regeneration require an active paracrine role of the microvascular endothelium, which in turn depends on angiogenic growth factors. Thus, we hypothesize that endothelial cells stimulate organ and tissue regeneration via production of bioactive EETs. To determine whether endothelial-derived EETs affect physiologic tissue growth in vivo, we used genetic and pharmacological tools to manipulate endogenous EET levels. We show that endothelial-derived EETs play a critical role in accelerating tissue growth in vivo, including liver regeneration, kidney compensatory growth, lung compensatory growth, wound healing, corneal neovascularization, and retinal vascularization. Administration of synthetic EETs recapitulated these results, whereas lowering EET levels, either genetically or pharmacologically, delayed tissue regeneration, demonstrating that pharmacological modulation of EETs can affect normal organ and tissue growth. We also show that soluble epoxide hydrolase inhibitors, which elevate endogenous EET levels, promote liver and lung regeneration. Thus, our observations indicate a central role for EETs in organ and tissue regeneration and their contribution to tissue homeostasis.
Motion of domain walls and the dynamics of kinks in the magnetic Peierls potential
Creators: name: Buijnsters, F. J.
name: Fasolino, A.
name: Katsnelson, M. I.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We study the dynamics of magnetic domain walls in the Peierls potential due to the discreteness of the crystal lattice. The propagation of a narrow domain wall (comparable to the lattice parameter) under the effect of a magnetic field proceeds through the formation of kinks in its profile. We predict that, despite the discreteness of the system, such kinks can behave like sine-Gordon solitons in thin films of materials such as yttrium iron garnets, and we derive general conditions for other materials. In our simulations we also observe long-lived breathers. We provide analytical expressions for the effective mass and limiting velocity of the kink in excellent agreement with our numerical results.
description: 12 pages, 9 figures (incl. supp. mat.)
Gewaltlosigkeit - die angemessene und wirksame Antwort auf menschliche Konflikte
Creators: name: Bstan-Vdzin-Rgya-Mtsho, Dalai Lama
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 39 Nr. 5 (2003): Concilium: Internationale Zeitschrift für Theologie, Band 39, Heft 5
Co-occurrence matrices of time series applied to literary works
Creators: name: Sparavigna, Amelia Carolina
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Recently, it has been proposed to analyse the literary works, plays or novels, using graphs to display the social network of their interacting characters. In this approach, the timeline of the literary work is lost, because the storyline is projected on a planar graph. However, timelines can be used to build some time series and analyse the work by means of vectors and matrices. These series can be used to describe the presence and relevance, not only of words in the text, but also of persons and places portrayed in the drama or novel. In this framework, we discuss here an approach with co-occurrence matrices plotted over time, concerning the presence of characters in the pages of a novel. These matrices are similar to those appearing in recurrence plots.
description: Literary experiments, Time series, Co-occurrence plots, Harry Potter
Blockchain for the circular economy: Theorizing blockchain's role in the transition to a circular economy through an empirical investigation
Creators: name: Böhmecke‐Schwafert, Moritz
name: Wehinger, Marie
name: Teigland, Robin
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 300 Sozialwissenschaften::330 Wirtschaft::330 Wirtschaft
subject: blockchain
subject: circular economy
subject: innovation
subject: sustainability
subject: transition

description: Blockchain is increasingly lauded as an enabler of the transition to a circular economy. While there is considerable conceptual research and some empirical studies on this phenomenon, scholars have yet to develop a theoretical model of blockchain's role in this transition. Grounded in the sustainability transition literature, this paper addresses this gap through the following research question: What role does blockchain play in the transition to a circular economy? Following an abductive approach, we conducted interviews with ground‐level experts implementing blockchain innovations for the circular economy across Europe and the United States. Through a thematic analysis, we derived a theoretical model of the relationships among (1) drivers and barriers of the transition to a circular economy, (2) blockchain innovation for the circular economy, (3) technical challenges of blockchain, and (4) the circular economy. While blockchain plays a moderating role, interviewees considered it only an infrastructural resource rather than a panacea.
Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease
Creators: name: Ren, R.
name: Oakley, R. H.
name: Cruz-Topete, D.
name: Boyle, M. C.
name: Schneider, M. D.
name: Myers, P. H.
name: Cidlowski, J. A.
name: Willis, M. S.
name: Bird, G. S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Stress is increasingly associated with heart disease. Glucocorticoids are primary stress hormones, yet their direct role in the heart is poorly understood. Mice lacking the glucocorticoid receptor specifically in cardiomyocytes die prematurely from heart failure. The deficiency in glucocorticoid signaling leads to the aberrant regulation of a large cohort of genes strongly associated with both cardiovascular and inflammatory disease processes. These findings reveal an obligate role for cardiomyocyte glucocorticoid receptors in maintaining normal heart function and define a paradigm for stress in cardiovascular disease.
Carboniferous magmatic records of central Mongolia and its implications for the southward subduction of the Mongol–Okhotsk Ocean
Creators: name: Zhu, Mingshuai
name: Miao, Laicheng
name: Zhang, Fuqin
name: Ganbat, Ariuntsetseg
name: Baatar, Munkhtsengel
name: Anaad, Chimedtseren
name: Yang, Shunhu
name: Wang, Zeli
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Science Policy

description: The now-extinct Palaeozoic to Mesozoic Mongol–Okhotsk Ocean is evidenced by the Mongol–Okhotsk suture, which stretches from central Mongolia to the Sea of Okhotsk. The geodynamics of southward subduction of the Mongol–Okhotsk Ocean remain enigmatic, especially whether the subduction began during the Carboniferous is highly debated. In this paper we present new zircon U–Pb ages and whole-rock geochemical data for the Carboniferous magmatic rocks in Northeast Mongolia. Zircon U–Pb dating indicates that the Adaatsag dacite, Northern Bayanjargalan gabbro-diorite and Bagannur pluton were emplaced at ca. 325 Ma, ca. 316 Ma, and ca. 305 Ma, respectively. Occurrences of these rocks together constitute a Carboniferous magmatic belt to the northwest of the Middle Gobi volcanic-plutonic belt. The ages of trapped zircon xenocrysts within the Bagannur pluton indicate that the basement of this magmatic belt is the Ereendavaa terrane. Geochemical analysis indicates that these magmatic rocks were formed in an Andean-type active margin, which provides robust evidence for southward subduction of the Mongol-Okhotsk Ocean during the Late Carboniferous. By combining all the available data, we argue that the onset of the Central Mongolia–Tsagaan Uul continental collision during the Late Carboniferous – Early Permian may have triggered the beginning of an active margin of the Mongol-Okhotsk Ocean along the northern coast of the Central Mongolia microcontinent.
Vergebung und Gerechtigkeit - die Chancen und die Pädagogik der Versöhnung
Creators: name: Reynolds, Robyn
Publisher: name: Concilium
Year: 1970

description: Concilium, Bd. 39 Nr. 5 (2003): Concilium: Internationale Zeitschrift für Theologie, Band 39, Heft 5
Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium
Creators: name: Vockley, Christopher M.
name: Gao, Xia
name: Newberry, Kimberly M.
name: Xue, Yan
name: Pauli, Florencia
name: Hogan, Brigid L. M.
name: Randell, Scott H.
name: Reddy, Timothy E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Most of the airways of the human lung are lined by an epithelium made up of ciliated and secretory luminal cells and undifferentiated basal progenitor cells. The integrity of this epithelium and its ability to act as a selective barrier are critical for normal lung function. In other epithelia, there is evidence that transcription factors of the evolutionarily conserved grainyheadlike (GRHL) family play key roles in coordinating multiple cellular processes required for epithelial morphogenesis, differentiation, remodeling, and repair. However, only a few target genes have been identified, and little is known about GRHL function in the adult lung. Here we focus on the role of GRHL2 in primary human bronchial epithelial cells, both as undifferentiated progenitors and as they differentiate in air–liquid interface culture into an organized mucociliary epithelium with transepithelial resistance. Using a dominant-negative protein or shRNA to inhibit GRHL2, we follow changes in epithelial phenotype and gene transcription using RNA sequencing or microarray analysis. We identify several hundreds of genes that are directly or indirectly regulated by GRHL2 in both undifferentiated cells and air–liquid interface cultures. Using ChIP sequencing to map sites of GRHL2 binding in the basal cells, we identify 7,687 potential primary targets and confirm that GRHL2 binding is strongly enriched near GRHL2-regulated genes. Taken together, the results support the hypothesis that GRHL2 plays a key role in regulating many physiological functions of human airway epithelium, including those involving cell morphogenesis, adhesion, and motility.
How unitizing affects annotation of cohesion
Creators: name: Ceccaldi, Eleonora
name: Lehmann-Willenbrock, Nale
name: Volta, Erica
name: Chetouani, Mohamed
name: Volpe, Gualtiero
name: Varni, Giovanna
Publisher: name: arXiv
Year: 2022
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: This paper investigates how unitizing affects external observers' annotation of group cohesion. We compared unitizing techniques belonging to these categories: interval coding, continuous coding, and a technique inspired by a cognitive theory on event perception. We applied such techniques for sampling coding units from a set of recordings of social interactions rich in behaviors related to cohesion. Then, we compared the cohesion scores the observers assigned to each coding unit. Results show that the three techniques can lead to suitable ratings and that the technique inspired to cognitive theories leads to scores reflecting variability in cohesion better than the other ones.
AI Education Isabel Fischer.pdfAI in Education - Findings and Recommendations
Creators: name: Fischer, Isabel
Publisher: name: figshare
Year: 2023
Subjects: classificationCode: 460299
subject: Artificial intelligence not elsewhere classified

description: Our full resources can be found here: https://warwick.ac.uk/fac/cross_fac/academy/activities/learningcircles/future-of-learning/
Strictly commutative models for E-infinity quasi-categories
Creators: name: Kodjabachev, Dimitar
name: Sagave, Steffen
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Topology (math.AT)
subject: Category Theory (math.CT)
subject: FOS: Mathematics

description: In this short note we show that E-infinity quasi-categories can be replaced by strictly commutative objects in the larger category of diagrams of simplicial sets indexed by finite sets and injections. This complements earlier work on diagram spaces by Christian Schlichtkrull and the second author.
description: v2: 7 pages, exposition improved. Accepted for publication in Homology, Homotopy and Applications
Geochemistry, sulfur and lead isotopic composition of hydrothermal sulfide from the Duanqiao hydrothermal field on the Southwest Indian Ridge: implications for ore genesis
Creators: name: Yang, Weifang
name: Liao, Shili
name: Dias, Ágata Alveirinho
name: Liang, Jin
name: Li, Wei
name: Ding, Teng
name: Tao, Chunhui
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Cancer
subject: Inorganic Chemistry

description: Hydrothermal activities on ultraslow-spreading ridges exhibit diverse characteristics, long histories with multiple participants, and might form large-scale, high-grade sulfide deposits. The Duanqiao hydrothermal field (DHF) is located at the segment with the thickest oceanic crust and a large axial magma chamber on the Southwest Indian Ridge, providing unique perspective of sulfide metallogenesis on ultraslow-spreading ridges. Previous studies revealed that DHF sulfide exhibits distinct features of enrichment of ore-forming elements in comparison with those of hydrothermal fields on sediment-starved mid-ocean ridges. However, the genesis and processes responsible for such differences remain poorly constrained. In this study, mineralogical, geochemical and S and Pb isotopic analyses were performed on relict sulfide mound samples to characterize DHF formation. The samples show clear concentric mineral zonation from the interior to the exterior wall. Assemblages of chalcopyrite, sphalerite, and pyrite are distributed mainly in the interior wall, whereas pyrite and marcasite are distributed mainly in the exterior wall. The low Cu content and Pb isotopic composition of the sulfide indicate that the metals are derived mainly from basement basalts. The δ34S values exhibit positive values distributed over a reasonably narrow range (2.42‰–7.97‰), which suggests approximately 62.1%–88.5% of S with basaltic origin. Compared with most hydrothermal fields along the sediment starved mid-ocean ridges, the DHF sulfide shows particularly high contents of Pb (263–2630 ppm), As (234–726 ppm), Sb (7.32–44.3 ppm), and Ag (35.2 to >100 ppm). The δ34S values exhibit an increasing tendency from the sample exterior to the interior. We propose that these features probably reflect the existence of a subsurface zone refining process. Our results provide new insight into the sulfide formation process and contribute to understanding the metallogenic mechanism of hydrothermal sulfides on ultraslow-spreading ridges.
The impact of internal company dynamics on sustainable circular business development: Insights from circular startups
Creators: name: Kolpinski, Charleen Von
name: Yazan, Devrim Murat
name: Fraccascia, Luca
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 300 Sozialwissenschaften::330 Wirtschaft::330 Wirtschaft
subject: circular business model
subject: circular economy
subject: circular startup
subject: internal dynamics
subject: small‐medium enterprises
subject: sustainability

description: The circular economy is commonly acknowledged as a solution to ecological problems such as resource depletion and waste emissions. New economic opportunities emerge by transitioning from a linear to a circular economy and innovative business models are needed to translate these opportunities into business reality. In recent years, researchers have investigated a variety of approaches to circular business models, but few studies have been conducted associating internal company dynamics with sustainable circular business approaches. Consequently, the purpose of this study is to investigate the internal dynamics of young and small-scale companies in Germany that adopt a sustainable circular business model. This study focuses on internal barriers, enablers, competences and drivers to sustainable circular business model implementation. A case-based research design was applied, drawing on semi-structured interviews with 12 founders of businesses and organisations with a sustainable circular business model. The study develops four strategies to overcome barriers to sustainable circular business model adoption in young and small-scale companies: (1) human-centeredness in all activities affected by circular business model adoption, (2) high commitment for circularity on the managerial level, (3) requirement of special skills and competences and (4) consideration of cultural aspects inside and outside the company. Further empirical research about established and international incumbents with a sustainable circular business model is needed to be able to compare the internal dynamics of big and small companies in international contexts.
Secure Indoor Location for Airport Environments
Creators: name: Santos-González, I
name: Rivero-García, A
name: Caballero-Gil, P
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: This work presents a secure novel solution based on inertial measurement units to provide indoor location and positioning in airports. The use of different technologies allows to locate people with precision in this kind of indoor places where the use of the GPS is not possible. The system has been developed thinking in the low cost and in a possible future expansion of this kind of systems to improve the Quality of Service of the users in airports. The use of QR codes and low cost IMU devices through the use of people smartphones ensure this premise. An Android application has been developed to show the applicability and performance of the system. The security in this kind of systems is essential. This kind of systems needs to avoid the traceability of the IMU devices when users are using it. To solve this problem, the FourQ elliptic curve has been used to generate a shared key using the elliptic curve Diffie-Hellman protocol. The key generated with the FourQ is used then to cipher all communications through the use of the SNOW 3G stream cipher. The developed system offers promising results.
Evolutionary etiology of high-grade astrocytomas
Creators: name: Miller, C. R.
name: Difilippantonio, S.
name: McCarthy, K. D.
name: Kafri, T.
name: Kutlu, B.
name: Gilbert, D.
name: Kozlov, S.
name: Bash, R.
name: O'Sullivan, T. N.
name: Bullitt, E.
name: Louis, D. N.
name: Zhang, Q.
name: Hood, L.
name: Yang, C.
name: Yin, C.
name: Song, Y.
name: Van Dyke, T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: High-grade astrocytomas (HGAs), including glioblastomas (GBMs), are the most common human brain tumors, and they remain fatal with no effective treatment. The most prevalent form, primary GBM, presents clinically as advanced disease, thus providing no access to or understanding of early stages. We report a comprehensive study in the mouse that establishes causal relationships and an evolutionary etiology in HGA development. Events yielding disease, both engineered and spontaneous, indicate grade-specific roles culminating in the development of GBMs with characteristics of primary GBMs, including molecular alignment with the mesenchymal subclass, asymptomatic early disease, and rapid emergence of high-grade aggressive cancer. These genetically engineered models provide a path to basic understanding of disease etiology and a window into diagnostic and therapeutic discovery.
On the maximal operators of Riesz logarithmic means of Vilenkin-Fourier series
Creators: name: Tephnadze, George
Publisher: name: arXiv
Year: 2014
Subjects: subject: Classical Analysis and ODEs (math.CA)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 42C10

description: The main aim of this paper is to investigate $\left( H_{p},L_{p}\right) $ and $\left( H_{p},L_{p,\infty }\right) $ type inequalities for maximal operators of Riesz logarithmic means of one-dimensional Vilenkin-Fourier series.
description: Vilenkin system, Riesz logarithmic means, martingale Hardy space. arXiv admin note: text overlap with arXiv:1410.6101, arXiv:1410.6416, arXiv:1410.7204, arXiv:1410.7635, arXiv:1410.6186, arXiv:1410.7075, arXiv:1410.6102
Sustainability and firm value in the oil and gas industry—A vicious circle?
Creators: name: Kaupke, Katharina
name: Knyphausen‐Aufseß, Dodo Zu
Publisher: name: Technische Universität Berlin
Year: 2022
Subjects: subject: 300 Sozialwissenschaften::330 Wirtschaft::330 Wirtschaft
subject: 3SLS
subject: corporate social responsibility
subject: firm value
subject: oil and gas industry
subject: sustainability

description: The relationship between sustainability (or CSR) and company value has been intensively researched in recent times. However, the specifics of individual industries have not been sufficiently taken into account. Our study aims to fill this research gap. We focus on the oil and gas industry as a particularly powerful and controversial industry. Based on legitimacy theory and institutional theory, we argue that the relationship between firm value and sustainability is negative in this industry. Our sample consists of 205 firms with 1515 observations. Using a simultaneous equation system (3SLS) to determine its direction, we find the two to be negatively interrelated in a vicious circle. Furthermore, we find evidence for a moderating role of the renewable energy share of a company's headquarter country as well as the company's industry segment. The explanatory power continues to hold with consideration of a profitability measure (Return on Sales) instead of firm value.
Experimental demonstration of radicaloid character in a RuV=O intermediate in catalytic water oxidation
Creators: name: Meyer, T. J.
name: Concepcion, J. J.
name: Alperovich, I.
name: Pushkar, Y.
name: Moonshiram, D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Water oxidation is the key half reaction in artificial photosynthesis. An absence of detailed mechanistic insight impedes design of new catalysts that are more reactive and more robust. A proposed paradigm leading to enhanced reactivity is the existence of oxyl radical intermediates capable of rapid water activation, but there is a dearth of experimental validation. Here, we show the radicaloid nature of an intermediate reactive toward formation of the O-O bond by assessing the spin density on the oxyl group by Electron Paramagnetic Resonance (EPR). In the study, an 17O-labeled form of a highly oxidized, short-lived intermediate in the catalytic cycle of the water oxidation catalyst cis,cis-[(2,2-bipyridine)2(H2O)RuIIIORuIII(OH2)(bpy)2]4+ was investigated. It contains Ru centers in oxidation states [4,5], has at least one RuV = O unit, and shows |Axx| = 60G 17O hyperfine splittings (hfs) consistent with the high spin density of a radicaloid. Destabilization of π-bonding in the d3 RuV = O fragment is responsible for the high spin density on the oxygen and its high reactivity.
The Cenomanian–Turonian Boundary Event (CTBE) as recorded in the northern margin of Africa: palaeoceanography of the Oceanic Anoxic Event (OAE-2), North-Central Tunisia
Creators: name: Soua, Mohamed
name: Asmi, Amina Mabrouk El
name: Zaghbib-Turki, Dalila
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences

description: Samples spanning the Cenomanian–Turonian transition at Guern Halfaya Section of North-Central Tunisia were analysed for elemental and isotopic chemostratigraphic characterization of the OAE-2 global anoxic event. Comparison with other published sections of the same age was achieved. These geochemical analyses, which cover the local Bahloul Formation, add new insights into the palaeoceanographic evolution of the southern Tethyan margin during the Cenomanian–Turonian transition. The use of discrete redox-sensitive and primary productivity-sensitive trace element data coupled to isotopic and biostratigraphic events is shown as leading proxies for the determination of prevailing warming palaeoceanographic conditions, in terms of productivity and climate, during the OAE-2 in the northern margin of Africa. Such event is believed to have generated one among the most significant source rocks of the region.
Building an Ethereum-Based Decentralized Vehicle Rental System
Creators: name: García-Moreno, N
name: Caballero-Gil, P
name: Caballero-Gil, C
name: Molina-Gil, J
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Blockchain technology, beyond cryptocurrencies, is called to be the new information exchange ecosystem due to its unique properties, such as immutability and transparency. The main objective of this work is to introduce the design of a decentralized rental system, which leverages smart contracts and the Ethereum public blockchain. The work started from an exhaustive investigation on the Ethereum platform, emphasizing the aspect of cryptography and all the technology behind this platform. In order to test the proposed scheme in a realistic use, the implementation of a web application for the rental of vehicles has been carried out. The application covers the entire vehicle rental process offered in traditional web applications, adding more autonomy and ease of use to users. Following Ethereum application development guidelines, all business logic is located in the smart contracts implemented in the Ethereum network, where these contracts control the entire vehicle rental system of customers. While this is a work in progress, the results obtained in the first proof of concept have been very promising.
Sequential sentence classification in research papers using cross-domain multi-task learning
Creators: name: Brack, Arthur
name: Entrup, Elias
name: Stamatakis, Markos
name: Buschermöhle, Pascal
name: Hoppe, Anett
name: Ewerth, Ralph
Publisher: name: Berlin ; Heidelberg ; New York : Springer
Year: 2024
Subjects: subject: Multi-task learning
subject: Scholarly communication
subject: Sequential sentence classification
subject: Transfer learning
subject: Zone identification
subject: Dewey Decimal Classification::000 | Allgemeines, Wissenschaft::070 | Nachrichtenmedien, Journalismus, Verlagswesen

description: The automatic semantic structuring of scientific text allows for more efficient reading of research articles and is an important indexing step for academic search engines. Sequential sentence classification is an essential structuring task and targets the categorisation of sentences based on their content and context. However, the potential of transfer learning for sentence classification across different scientific domains and text types, such as full papers and abstracts, has not yet been explored in prior work. In this paper, we present a systematic analysis of transfer learning for scientific sequential sentence classification. For this purpose, we derive seven research questions and present several contributions to address them: (1) We suggest a novel uniform deep learning architecture and multi-task learning for cross-domain sequential sentence classification in scientific text. (2) We tailor two transfer learning methods to deal with the given task, namely sequential transfer learning and multi-task learning. (3) We compare the results of the two best models using qualitative examples in a case study. (4) We provide an approach for the semi-automatic identification of semantically related classes across annotation schemes and analyse the results for four annotation schemes. The clusters and underlying semantic vectors are validated using k-means clustering. (5) Our comprehensive experimental results indicate that when using the proposed multi-task learning architecture, models trained on datasets from different scientific domains benefit from one another. Our approach significantly outperforms state of the art on full paper datasets while being on par for datasets consisting of abstracts.
Genetic heterogeneity of diffuse large B-cell lymphoma
Creators: name: Banerjee, Anjishnu
name: Srivastava, Gopesh
name: Bernal-Mizrachi, Leon
name: Hsi, Eric D.
name: Walsh, Katherine
name: Czader, Magdalena
name: Mann, Karen P.
name: Rizzieri, David A.
name: Ni, Ting
name: Byrd, John C.
name: Lugar, Patricia L.
name: Dunphy, Cherie
name: Zhang, Jenny
name: Gordon, Leo I.
name: Evens, Andrew
name: Johnson, Amy J.
name: Fan, Alice
name: Naresh, Kikkeri
name: Gill, Javed I.
name: Luftig, Micah A.
name: Zhu, Jun
name: Smith, Lisa L.
name: Mieczkowski, Piotr A.
name: Choi, William
name: Au, Wing Yan
name: Liu, Qingquan
name: Richards, Kristy L.
name: Flowers, Christopher
name: Lagoo, Anand S.
name: Grubor, Vladimir
name: Love, Cassandra L.
name: Jima, Dereje
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma in adults. The disease exhibits a striking heterogeneity in gene expression profiles and clinical outcomes, but its genetic causes remain to be fully defined. Through whole genome and exome sequencing, we characterized the genetic diversity of DLBCL. In all, we sequenced 73 DLBCL primary tumors (34 with matched normal DNA). Separately, we sequenced the exomes of 21 DLBCL cell lines. We identified 322 DLBCL cancer genes that were recurrently mutated in primary DLBCLs. We identified recurrent mutations implicating a number of known and not previously identified genes and pathways in DLBCL including those related to chromatin modification (ARID1A and MEF2B), NF-κB (CARD11 and TNFAIP3), PI3 kinase (PIK3CD, PIK3R1, and MTOR), B-cell lineage (IRF8, POU2F2, and GNA13), and WNT signaling (WIF1). We also experimentally validated a mutation in PIK3CD, a gene not previously implicated in lymphomas. The patterns of mutation demonstrated a classic long tail distribution with substantial variation of mutated genes from patient to patient and also between published studies. Thus, our study reveals the tremendous genetic heterogeneity that underlies lymphomas and highlights the need for personalized medicine approaches to treating these patients.
Opportunities and conditions to learn (OCL): A conceptual framework
Creators: name: Perry, Laura B.
name: Thier, Michael
name: Beach, Paul
name: Anderson, Ross C.
name: Thoennessen, Niklas-Max
name: Roberts, Philip
Publisher: name: Dordrecht : Springer Science + Business Media B.V.
Year: 2023
Subjects: subject: Achievement
subject: Inequality
subject: Learning
subject: Opportunity to learn
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie::370 | Erziehung, Schul- und Bildungswesen

description: “Opportunity to learn” has evolved into an umbrella phrase for describing a large range of settings, resources, structures, and processes. The aim of this study is to develop a conceptual framework that can accommodate a wide range of opportunities to learn, not just those provided by teachers in classrooms. An inclusive framework can bring together diverse studies about opportunity to learn, increasing synergies and uncovering interconnections, and making more visible marginalized forms of learning. It can also be used as a framework for holding governments, education authorities, and policy makers accountable for providing equitable opportunities and conditions to learn. This article presents a three-dimensional conceptual framework of opportunities and conditions to learn (OCL) that captures (a) notions of what opportunities exist and where those opportunities exist and opportunities offered by whom, as well as (b) a spate of conditions that can shape those opportunities.
Impact of reconstituted cytosol on protein stability
Creators: name: Sarkar, M.
name: Smith, A. E.
name: Pielak, G. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The cell cytoplasm contains a complex array of macromolecules at concentrations exceeding 300 g/L. The natural, most relevant state of a biological macromolecule is thus a “crowded” one. Moving quantitative protein chemistry from dilute solution to the inside of living cells represents a major frontier that will affect not only our fundamental biological knowledge, but also efforts to produce and stabilize protein-based pharmaceuticals. We show that the bacterial cytosol actually destabilizes our test protein, contradicting most theoretical predictions, but in agreement with a novel Escherichia coli model.
Assembling and Regulating of Transition Metal‐Based Heterophase Vanadates as Efficient Oxygen Evolution Catalysts
Creators: name: Shao, Wenjie
name: Xiao, Mingjun
name: Yang, Chengdong
name: Cheng, Menghao
name: Cao, Sujiao
name: He, Chao
name: Zhou, Mi
name: Ma, Tian
name: Cheng, Chong
name: Li, Shuang
Publisher: name: Technische Universität Berlin
Year: 2021
Subjects: subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften
subject: electrocatalysts
subject: heterophase nanostructures
subject: oxygen evolution reaction
subject: transition metal vanadates
subject: water splitting

description: Developing efficient, durable, and low-cost earth-abundant elements-based oxygen evolution reaction (OER) catalysts by rapid and scalable strategies is of great importance for future sustainable electrochemical hydrogen production. The earth-abundant high-valency metals, especially vanadium, can modulate the electronic structure of 3d metal oxides and oxyhydroxides and offer the active sites near-optimal adsorption energies for OER intermediates. Here, the authors propose a facile assembling and regulating strategy to controllably synthesize a serial of transition metal (CoFe, NiFe, and NiCo)-based vanadates for efficient OER catalysis. By tuning the reaction concentrations, NiFe-based vanadates with different crystallinities can be facilely regulated, where the catalyst with moderate heterophase (mixed crystalline and amorphous structures) shows the best OER catalytic activity in terms of low overpotential (267 mV at the current density of 10 mA cm−2), low Tafel slope (38 mV per decade), and excellent long-term durability in alkaline electrolyte, exceeding its noble metal-based counterparts (RuO2) and most current existing OER catalysts. This work not only reports a facile and controllable method to synthesize a series of vanadates-based catalysts with heterophase nanostructures for high-performance OER catalysis, but also may expand the scope of designing cost-effective transition metal-based electrocatalysts for water splitting.
Vulnerability and Response-Ability in the Pandemic Marketplace: Developing an Ethic of Care for Provisioning in Crisis
Creators: name: Geiger, Susi
name: Galasso, Ilaria
name: Hangel, Nora
name: Lucivero, Federica
name: Watts, Gemma
Publisher: name: Dordrecht : Springer
Year: 2023
Subjects: subject: Consumption ethics
subject: Covid-19
subject: Crisis
subject: Ethics of care
subject: Relational ethics
subject: Response-ability
subject: Shopping
subject: Solidarity
subject: Dewey Decimal Classification::300 | Sozialwissenschaften, Soziologie, Anthropologie

description: This paper draws on the ethics of care to investigate how citizens grappled with ethical tensions in the mundane practice of grocery shopping at the height of the Covid-19 pandemic. We use this case to address the broader question of what it means ‘to care’ in the context of a crisis. Based on a qualitative longitudinal cross-country interview study, we find that the pandemic transformed ordinary shopping spaces into places fraught with a sense of fear and vulnerability. Being forced to face one’s own vulnerability created an opportunity for individuals to relate to one another as significant others through a sense of “response-ability”, or the capacity of people to respond to ethical demands through situated ethical reasoning. We argue for a practical ethos of care in which seemingly small decisions such as how often to go shopping and how much to buy of a particular product serve as a means to relate to both specified and generalized others—and through this, ‘care with’ society. Our study contributes to displacing the continuing prevalence of an abstract and prescriptive morality in consumption ethics with a situated and affective politics of care. This vocabulary seems better suited to reflect on the myriad of small and unheroic care acts in times of crisis and beyond.
Self-similarity, Aboav-Weaire's and Lewis' laws in weighted planar stochastic lattice
Creators: name: Dayeen, F. R.
name: Hassan, M. K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: In this article, we show that the block size distribution function in the weighted planar stochastic lattice (WPSL), which is a multifractal and whose dual is a scale-free network, exhibits dynamic scaling. We verify it numerically using the idea of data-collapse. As the WPSL is a space-filling cellular structure, we thought it was worth checking if the Lewis and the Aboav-Weaire laws are obeyed in the WPSL. To this end, we find that the mean area $_k$ of blocks with $k$ neighbours grow linearly up to $k=8$, and hence the Lewis law is obeyed. However, beyond $k>8$ we find that $_k$ grows exponentially to a constant value violating the Lewis law. On the other hand, we show that the Aboav-Weaire law is violated for the entire range of $k$. Instead, we find that the mean number of neighbours of a block adjacent to a block with $k$ neighbours is approximately equal to six, independent of $k$.
description: 6 pages, 6 figures
Joint astrometric solution of Hipparcos and Gaia: A recipe for the Hundred Thousand Proper Motions project
Creators: name: Michalik, Daniel
name: Lindegren, Lennart
name: Hobbs, David
name: Lammers, Uwe
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The first release of astrometric data from Gaia is expected in 2016. It will contain the mean stellar positions and magnitudes from the first year of observations. For more than 100 000 stars in common with the Hipparcos Catalogue it will be possible to compute very accurate proper motions due to the time difference of about 24 years between the two missions. This Hundred Thousand Proper Motions (HTPM) project will be part of the first release. Our aim is to investigate how early Gaia data can be optimally combined with information from the Hipparcos Catalogue in order to provide the most accurate and reliable results for HTPM. The Astrometric Global Iterative Solution (AGIS) was developed to compute the astrometric core solution based on the Gaia observations and will be used for all releases of astrometric data from Gaia. We adapt AGIS to process Hipparcos data in addition to Gaia observations, and use simulations to verify and study the joint solution method. For the HTPM stars we predict proper motion accuracies between 14 and 134 muas/yr, depending on stellar magnitude and amount of Gaia data available. Perspective effects will be important for a significant number of HTPM stars, and in order to treat these effects accurately we introduce a scaled model of kinematics. We define a goodness-of-fit statistic which is sensitive to deviations from uniform space motion, caused for example by binaries with periods of 10-50 years. HTPM will significantly improve the proper motions of the Hipparcos Catalogue well before highly accurate Gaia- only results become available. Also, HTPM will allow us to detect long period binary and exoplanetary candidates which would be impossible to detect from Gaia data alone. The full sensitivity will not be reached with the first Gaia release but with subsequent data releases. Therefore HTPM should be repeated when more Gaia data become available.
description: Revised manuscript following referee report. Accepted for publication in A&A
Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer
Creators: name: Knight, J. F.
name: Mulligan, A. M.
name: Davis, R. R.
name: Saleh, S. M. I.
name: Park, M.
name: Hallett, M. T.
name: Chughtai, N.
name: Herschkowitz, J. I.
name: Prat, A.
name: Cardiff, R. D.
name: Lesurf, R.
name: Zhao, H.
name: Zuo, D.
name: Naujokas, M. A.
name: Pinnaduwage, D.
name: Gregg, J. P.
name: Muller, W. J.
name: Andrulis, I. L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Triple-negative breast cancers lack targeted therapies and are subdivided into molecular subtypes, including basal and claudin-low. Preclinical models representing these subtypes are limited. We have developed a murine model in which mammary gland expression of a receptor tyrosine kinase (MET) and loss of tumor suppressor gene p53 (Trp53), synergize to promote tumors with pathological and molecular features of claudin-low breast cancer. These tumors require MET signaling for proliferation, as well as mesenchymal characteristics, which are key features of claudin-low biology. This work associates MET expression and p53 loss with claudin-low breast cancers and highly proliferative breast cancers of poor outcome.
Microclimate moderates plant responses to macroclimate warming
Creators: name: Kelly, D. L.
name: De Frenne, P.
name: Rodriguez-Sanchez, F.
name: Schultz, J.
name: Newman, M.
name: Walther, G.-R.
name: Eriksson, O.
name: Naaf, T.
name: Coomes, D. A.
name: Peterken, G.
name: Van Calster, H.
name: Verstraeten, G.
name: Baeten, L.
name: Sonnier, G.
name: Petrik, P.
name: Brunet, J.
name: Heinken, T.
name: Hermy, M.
name: White, P. S.
name: Waller, D. M.
name: Mitchell, F. J. G.
name: Decocq, G. M.
name: Vellend, M.
name: Hedl, R.
name: Jenkins, M. A.
name: Kirby, K. J.
name: Bernhardt-Romermann, M.
name: Dierschke, H.
name: Brown, C. D.
name: Gilliam, F. S.
name: Cornelis, J.
name: Hommel, P.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Around the globe, climate warming is increasing the dominance of warm-adapted species—a process described as “thermophilization.” However, thermophilization often lags behind warming of the climate itself, with some recent studies showing no response at all. Using a unique database of more than 1,400 resurveyed vegetation plots in forests across Europe and North America, we document significant thermophilization of understory vegetation. However, the response to macroclimate warming was attenuated in forests whose canopies have become denser. This microclimatic effect likely reflects cooler forest-floor temperatures via increased shading during the growing season in denser forests. Because standing stocks of trees have increased in many temperate forests in recent decades, microclimate may commonly buffer understory plant responses to macroclimate warming.
GO_24, files from linear-scaling DFT and non-bonded parameters calculations
Creators: name: Pinto, Alexandre V.
Publisher: name: Zenodo
Year: 2022

description: Coordinates, topology, electron density cube file and files from Chargemol analysis for GO_24 obtained through Linear-Scaling Calculations in CP2K (check https://doi.org/10.1021/acs.jpcb.2c06037)
Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM
Creators: name: Hahn, K. M.
name: Digman, M. A.
name: Hinde, E.
name: Gratton, E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Here we present a fluctuation-based approach to biosensor Förster resonance energy transfer (FRET) detection that can measure the molecular flow and signaling activity of proteins in live cells. By simultaneous use of the phasor approach to fluorescence lifetime imaging microscopy (FLIM) and cross–pair correlation function (pCF) analysis along a line scanned in milliseconds, we detect the spatial localization of Rho GTPase activity (biosensor FRET signal) as well as the diffusive route adopted by this active population. In particular we find, for Rac1 and RhoA, distinct gradients of activation (FLIM-FRET) and a molecular flow pattern (pCF analysis) that explains the observed polarized GTPase activity. This multiplexed approach to biosensor FRET detection serves as a unique tool for dissection of the mechanism(s) by which key signaling proteins are spatially and temporally coordinated.