cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Entwicklung eines neuartigen Ansatzes zur therapeutischen Vakzinierung chronischer HBV-Infektionen
Creators: name: Zahn, Tobias
Publisher: name: UNSPECIFIED
Year: 2020

description: Aktuell leiden weltweit etwa 257 Millionen Menschen an einer chronischen Hepatitis-B-Virus- Infektion. In den meisten Fällen ist eine ungenügende T-Zellantwort für die Entwicklung einer Chronizität verantwortlich. Um eine ausreichende zelluläre, zytotoxische T-Zellantwort hervorzurufen und die Produktion neutralisierender Antikörper zu induzieren, wurde eine neuartige Impfstoffplattform etabliert, welche auf modifizierten, zellpermeablen Capsiden des Hepatitis-B-Virus (HBV) basiert. Die Permeabilität wurde durch die Fusion des Membran-permeablen Peptids Translocation motif (TLM) an die HBV Core-Protein- Monomere erreicht, aus welchen sich das Capsid assembliert (TLMcapside). Durch die Insertion eines Strep-tagIII in die Spike-tip Domäne, welche sich auf der Oberfläche der Capside befindet, können Antigene, welche mit Streptavidin fusioniert wurden, flexibel auf die Trägercapside geladen werden. In dieser Arbeit wurden die Domänen PreS1 und PreS2 der HBV-Oberflächenproteine mit monomerem Streptavidin fusioniert (mSA_preS1/2), um sie als Antigene auf die Oberfläche der Capside zu laden. Antigene und Capside wurden in bakteriellen Expressionssystemen produziert und mittels Affinitätschromatografie gereinigt. Die Bindung zwischen Antigen und Capsid wurde mittels Oberflächenplasmonenresonanzspektroskopie, Transmissionselektronenmikroskopie und Dichtegradientenzentrifugation charakterisiert. Unter Verwendung von konfokaler Laser- scanning-Mikroskopie und in-vivo-Imaging konnte die Membranpermeabilität der mSA_preS1/2-beladenen TLMcapside und deren Ausbreitung durch Zellen, Hautschichten, Organe und den gesamten Organismus festgestellt werden. Die Immunisierung von Mäusen mit den zellpermeablen, beladenen Capsiden führte einerseits zu einer starken humoralen Immunantwort mit HBV-spezifischen neutralisierenden Antikörpern und andererseits zu einer spezifischen T-Zellantwort, welche in der Eliminierung von HBV-positiven Zellen resultierte. Die Membranpermeabilität dieser Trägercapside ermöglicht zudem eine Nadel-freie, nichtinvasive Verabreichung von Antigen-beladenen Capsiden. Dies wurde durch die Immunisierung mithilfe von Pflastern über die transdermale Route sowie über die oral- mukosale Aufnahme über die Mundschleimhäute beobachtet. Bei erfolgreicher Immunisierung konnte somit eine HBV-spezifische T-Zell- und B-Zellantwort induziert werden. Die erhobenen Daten weisen darauf hin, dass die permeablen mSA_preS1/2- beladenen TLMcapside die Kapazität besitzen, eine starke, zelluläre sowie eine neutralisierende, humorale Immunantwort auszulösen, weshalb sie als therapeutisches Vakzin gegen chronische HBV-Infektionen eingesetzt werden könnten. Zusätzlich ermöglicht die Zellpermeabilität dieser Impfstoffplattform den Antigentransfer über mehrere Zellschichten und erlaubt somit alternative, nichtinvasive Routen wie oral-mukosale und transdermale Immunisierung.
Figure S3 from Does behaviour affect the dispersal of flatback post-hatchlings in the Great Barrier Reef?
Creators: name: Wildermann, Natalie
name: Critchell, Kay
name: Fuentes, Mariana M. P. B.
name: Limpus, Colin
name: Wolanski, Eric
name: Hamann, Mark
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60302 Biogeography and Phylogeography
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Comparison of the dispersal success for each swimming parameter used to model the dispersal of flatback turtles. Dispersal success (percentage of s-flatbacks in inshore waters) for each of the swimming parameters we evaluated in the sensitivity analysis: (a) swimming speed, (b) swimming direction, (c) proportion of time swimming per day, and (d) the day the post-frenzy swimming behaviour started. . For each scenario, the dispersal success for Wild Duck Island, Peak Island. Dispersal success are Very low (≤ 25%), Low (25.01 – 50%), Medium (51.01 – 75%) and High (> 75%). For all scenarios s-flatbacks were modelled for 120 days until 00h on 2nd May 2012.
Preactivation-Based, One-Pot Combinatorial Synthesis of Heparin-like Hexasaccharides for the Analysis of Heparin-Protein Interactions
Creators: name: Xu, Yongmei
name: Sun, Bin
name: Huang, Xuefei
name: Tirachinapally, Gopinath
name: Dulaney, Steven
name: Wang, Zhen
name: Liu, Renpeng
name: Liu, Jian
name: Yang, Bo
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Heparin (HP) and heparan sulfate (HS) play important roles in many biological events. Increasing evidence has shown that the biological functions of HP and HS can be critically dependent upon their precise structures, including the position of the iduronic acids and sulfation patterns. However, unraveling the HP code has been extremely challenging due to the enormous structural variations. To overcome this hurdle, we investigated the possibility of assembling a library of HP/HS oligosaccharides using a preactivation-based, one-pot glycosylation method. A major challenge in HP/HS oligosaccharide synthesis is stereoselectivity in the formation of the cis-1,4-linkages between glucosamine and the uronic acid. Through screening, suitable protective groups were identified on the matching glycosyl donor and acceptor, leading to stereospecific formation of both the cis-1,4- and trans-1,4-linkages present in HP. The protective group chemistry designed was also very flexible. From two advanced thioglycosyl disaccharide intermediates, all of the required disaccharide modules for library preparation could be generated in a divergent manner, which greatly simplified building-block preparation. Furthermore, the reactivity-independent nature of the preactivation-based, one-pot approach enabled us to mix the building blocks. This allowed rapid assembly of twelve HP/HS hexasaccharides with systematically varied and precisely controlled backbone structures in a combinatorial fashion. The speed and the high yields achieved in glycoassembly without the need to use a large excess of building blocks highlighted the advantages of our approach, which can be of general use to facilitate the study of HP/HS biology. As a proof of principle, this panel of hexasaccharides was used to probe the effect of backbone sequence on binding with the fibroblast growth factor-2 (FGF-2). A trisaccharide sequence of 2-O-sulfated iduronic acid flanked by N-sulfated glucosamines was identified to be the minimum binding motif and N-sulfation was found to be critical. This provides useful information for further development of more potent compounds towards FGF-2 binding, which can have potential applications in wound healing and anticancer therapy.
(3433) Arthur Ball
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
[ePub] PERDIDAS DE RISA descargar gratis
Creators: name: Burrow
Publisher: name: Zenodo
Year: 2024

description: PERDIDAS DE RISA de SILVIA ABRIL

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Ficha técnica

PERDIDAS DE RISA

SILVIA ABRIL

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788491398837

Editorial: HARPERCOLLINS

Año de edición: 2023

 

 

 

 

 

Amazon descarga libros en cinta PERDIDAS DE RISA FB2 RTF (Spanish Edition) 9788491398837

 

Overview

A los 50, la puñetera crisis no te pilla por sorpresa. Te pilla medio ciega, menopáusica y con tus primeros achaques. Es en ese punto de inflexión que a la peña le coge la pájara de pensar todo aquello que le queda por hacer. Que si tirarse en paracaídas, que si hacerse un tattoo, que si probar el poliamor… Amigas, ¿a quién queremos engañar? Ya no nos queda tanta energía. Os propongo algo mejor: echemos la vista atrás y repasemos todo aquello que SÍ hemos vivido. Ha sido emocionante, divertido y también humillante, para qué negarlo. Pero, sobre todo, podemos decir que lo hemos vivido y, lo mejor, SUPERADO. Este libro habla de mí. Pero creo que también de todas vosotras. Leedlo. Nos reiremos juntas. Por no decir que nos vamos a mear. Y me temo, que será literal. Vamos a acabar todas con Pérdidas de risa.
Part II, Free Actions of Compact Groups on C*-Algebras
Creators: name: Schwieger, Kay
name: Wagner, Stefan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Operator Algebras (math.OA)
subject: Quantum Algebra (math.QA)
subject: FOS: Mathematics
subject: 46L85, 37B05 (primary), 55R10, 16D70 (secondary)

description: We study a simple subclass of free actions of non-Abelian groups on unital C*-algebras, namely cleft actions. These are characterized by the fact that the associated noncommutative vector bundles are trivial. In particular, we provide a complete classification theory for these actions and describe its relations to classical principal bundles.
(3434) John Robert Ruck Keene
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
[PDF] INDIGNO DE SER HUMANO descargar gratis
Creators: name: Hanson
Publisher: name: Zenodo
Year: 2024

description: INDIGNO DE SER HUMANO de OSAMU DAZAI

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Ficha técnica

INDIGNO DE SER HUMANO

OSAMU DAZAI

Número de páginas: 124

Idioma: CASTELLANO

Formatos: Pdf, ePub, MOBI, FB2

ISBN: 9788493741372

Editorial: SAJALIN EDITORES

Año de edición: 2010

 

 

 

 

 

Descargas de audiolibros en alemán INDIGNO DE SER HUMANO de OSAMU DAZAI FB2

 

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Publicada por primera vez en 1948, Indigno de ser humano es una de las novelas más célebres de la literatura japonesa contemporánea. Su polémico y brillante autor, Osamu Dazai, incorporó numerosos episodios de su turbulenta vida a los tres cuadernos que conforman esta novela y que narran, en primera persona y de forma descarnada, el progresivo declive de Yozo, joven estudiante de provincias que lleva una vida disoluta en Tokio. Repudiado por su familia tras un intento de suicidio e incapaz de vivir en armonía con sus hipócritas semejantes, Yozo malvive como dibujante de historietas y subsiste gracias a la ayuda de mujeres que se enamoran de él pese a su alcoholismo y adicción a la morfina.
[Kindle] Un audacieux pari download
Creators: name: Marroquin
Publisher: name: Zenodo
Year: 2024

description: Un audacieux pari pan Laura Lee Guhrke, Catherine Berthet

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Caractéristiques

Un audacieux pari

Laura Lee Guhrke, Catherine Berthet

Nb. de pages: 386

Format: Pdf, ePub, MOBI, FB2

ISBN: 9782290392089

Editeur: J'ai Lu

Date de parution: 2024

 

 

 

Téléchargement gratuit en ligne de livres électroniques pdf Un audacieux pari (Litterature Francaise) 9782290392089 par Laura Lee Guhrke, Catherine Berthet

 

Overview

Parce que ses amis se moquent d'une petite libraire trop insolente à leur goût, Max, duc de Westbourne, se lance dans une folle aventure : il a six semaines pour métamorphoser Evangeline Harlow en reine de beauté et faire d'elle la nouvelle coqueluche de Londres ! Sacré défi, qui promet d'être fort distrayant. Mais quand le papillon sort de sa chrysalide, Max n'a plus du tout envie de le laisser s'envoler.
Read [Pdf]> The White Book by Han Kang
Creators: name: Tran
Publisher: name: Zenodo
Year: 2024

description: The White Book by Han Kang

 

 

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The White Book

Han Kang

Page: 160

Format: pdf, ePub, mobi, fb2

ISBN: 9780525573067

Publisher: Crown/Archetype

 

Amazon kindle books free downloads uk The White Book in English

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Dynamic Changes of Physicochemical Properties of Pineapple Juice During Fermentation with Allochthonous and Autochthonous Yeasts under Different Conditions
Creators: name: On-Ong Chanprasartsuk
Publisher: name: Mahasarakham University
Year: 2020
Subjects: Allochthonous yeast, autochthonous yeast, fermentation, fruit juice, pineapple

description: Science Technology and Engineering Journal (STEJ), 6, 1, 67-77
VHL and PTEN loss coordinate to promote mouse liver vascular lesions
Creators: name: Jude Samulski, R.
name: Kimryn Rathmell, W.
name: Sanford, Christie A.
name: Sun, Junjiang
name: Choi, Vivian
name: Chen, Shufen
name: Van Dyke, Terry
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Von Hippel-Lindau (VHL) inactivation develops a tumor syndrome characterized by highly vascularized tumors as a result of hypoxia inducible factors (HIF) stabilization. The most common manifestation is the development of hemangioblastomas typically located in the central nervous system and other organs including the liver. PTEN (Phosphatase and tension homologue deleted on chromosome 10) inactivation also upregulates HIF-1α and may take part in promoting vascular lesions in tumors. The coordinate effect of loss of these tumor suppressors on HIF levels, and the subsequent effect on vascular lesion formation would elucidate the potential for mechanisms to modify HIF dosage supplementally and impact tumor phenotype. We therefore employed models of somatic conditional inactivation of Vhl, Pten, or both tumor suppressor genes in individual cells of the liver by Cre-loxP recombination to study the cooperativity of these two tumor suppressors in preventing tumor formation. Nine months after tumor suppressor inactivation, Vhl conditional deletion (VhlloxP/loxP) mice showed no abnormalities, Pten conditional deletion (PtenloxP/loxP) mice developed liver steatosis and focal nodular expansion of hepatocytes containing lipid droplet and fat. Vhl and Pten conditional deletion (VhlloxP/loxP; PtenloxP/loxP) mice, however, developed multiple cavernous liver lesions reminiscent of hemangioblastoma. Liver hemangioblastomas in VHL disease may, therefore, require secondary mutation in addition to VHL loss of heterozygosity which is permissive for vascular lesion development or augments levels of HIF-1α.
title: Structural Studies of the Solid-Liquid Interface - Reactions at the Noble Electrode Surface
Creators: name: Beane, Jack William
Publisher: name: University of Liverpool Repository
Year: 2022

description: Surface x-ray diffraction (SXRD) has been employed in the study of the electrochemical interface for a number of electrode surface structures. The technique is employed in situ to obtain detail on the atomic structure of model single crystal electrode surfaces. The potential dependence of the hexagonal reconstructions of gold surfaces (Au(001) and Au(111)) in hydroxide electrolyte solutions in the presence and absence of CO molecules were investigated by SXRD. Results indicated that the compressibility of the reconstructed surface structures depended on a build up of charge at the surface at negative electrode potentials and that, with CO, the surfaces are locked into highly compressed phases. The influence of cation species on the Au(111) surface reconstruction was also investigated, finding that the cation had an influence on the sensitivity of the surface reconstruction to the applied potential. Phosphate adsorption on Cu(111) was also investigated in situ by SXRD. Results show that a mixed copper-oxygen layer is formed, and the surface exhibits a reversible, potential dependent change in roughening. Experiments also reveal the importance of surface preparation, as different preparation methods are shown to produce very different surface morphologies. The surface structures formed during halide adsorption and Pb UPD at the Cu(001) surface were investigated by resonant SXRD. Structural characterisations of the adlayer and UPD structures on Cu(001) were carried out, before coupling surface diffraction and spectroscopic measurements to obtain detail on the charge distribution for different atoms in the surface structure. Results show that iodine exhibits similar behaviour to that previously reported for other halide ions, and for the UPD Pb structure formed on Cu(001), a potential dependent change in the charge distribution for atoms at the surface was observed between -0.34 V and -0.22 V.
The radiation stability of glycine in solid CO2 - in situ laboratory measurements with applications to Mars
Creators: name: Gerakines, P. A.
name: Hudson, R. L.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: The detection of biologically important, organic molecules on Mars is an important goal that may soon be reached. However, the current small number of organic detections at the Martian surface may be due to the harsh UV and radiation conditions there. It seems likely that a successful search will require probing the subsurface of Mars, where penetrating cosmic rays and Solar energetic particles dominate the radiation environment, with an influence that weakens with depth. Toward the goal of understanding the survival of organic molecules in cold radiation-rich environments on Mars, we present new kinetics data on the radiolytic destruction of glycine diluted in frozen carbon dioxide. Rate constants were measured in situ with infrared spectroscopy, without additional sample manipulation, for irradiations at 25, 50, and 75 K with 0.8-MeV protons. The resulting half-lives for glycine in CO2-ice are compared to previous results for glycine in H2O-ice and show that glycine in CO2-ice is much less stable in a radiation environment, with destruction rate constants ~ 20-40 times higher than glycine in H2O-ice. Extrapolation of these results to conditions in the Martian subsurface results in half-lives estimated to be less than 100-200 million years even at depths of a few meters.
description: 20 pages, 3 tables, 5 figures, for more information go to http://science.gsfc.nasa.gov/691/cosmicice
PDF [Download] When We Lied by Claire Contreras
Creators: name: Shaffer
Publisher: name: Zenodo
Year: 2024

description: When We Lied by Claire Contreras

 

 

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When We Lied

Claire Contreras

Page: 448

Format: pdf, ePub, mobi, fb2

ISBN: 9781733041195

Publisher: Claire Contreras

 

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(3426) Margaret Reed
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Numerical bifurcation analysis of two coupled FitzHugh-Nagumo oscillators
Creators: name: Hoff, Anderson
name: Santos, Juliana V. dos
name: Manchein, Cesar
name: Albuquerque, Holokx A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: The behavior of neurons can be modeled by the FitzHugh-Nagumo oscillator model, consisting of two nonlinear differential equations, which simulates the behavior of nerve impulse conduction through the neuronal membrane. In this work, we numerically study the dynamical behavior of two coupled FitzHugh-Nagumo oscillators. We consider unidirectional and bidirectional couplings, for which Lyapunov and isoperiodic diagrams were constructed calculating the Lyapunov exponents and the number of the local maxima of a variable in one period interval of the time-series, respectively. By numerical continuation method the bifurcation curves are also obtained for both couplings. The dynamics of the networks here investigated are presented in terms of the variation between the coupling strength of the oscillators and other parameters of the system. For the network of two oscillators unidirectionally coupled, the results show the existence of Arnold tongues, self-organized sequentially in a branch of a Stern-Brocot tree and by the bifurcation curves it became evident the connection between these Arnold tongues with other periodic structures in Lyapunov diagrams. That system also present multistability shown in the planes of the basin of attractions.
description: 9 pages and 8 figures
PDF [Download] The Big Penis Book by Dian Hanson
Creators: name: Murrell
Publisher: name: Zenodo
Year: 2024

description: The Big Penis Book by Dian Hanson

 

 

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The Big Penis Book

Dian Hanson

Page: 192

Format: pdf, ePub, mobi, fb2

ISBN: 9783836578912

Publisher: Taschen America, LLC

 

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[PDF EPUB] Download Seven Empty Houses by Samanta Schweblin, Megan McDowell Full Book
Creators: name: Ouellette
Publisher: name: Zenodo
Year: 2024

description: Seven Empty Houses by Samanta Schweblin, Megan McDowell

 

 

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Seven Empty Houses

Samanta Schweblin, Megan McDowell

Page: 208

Format: pdf, ePub, mobi, fb2

ISBN: 9780525541394

Publisher: Penguin Publishing Group

 

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Figure S2. S-flatback distribution probabilities from Peak Island after (a) 3 days and (b) 120 days of passive drift (scenarios PD-TP-neap/spring) from Does behaviour affect the dispersal of flatback post-hatchlings in the Great Barrier Reef?.
Creators: name: Wildermann, Natalie
name: Critchell, Kay
name: Fuentes, Mariana M. P. B.
name: Limpus, Colin
name: Wolanski, Eric
name: Hamann, Mark
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60302 Biogeography and Phylogeography
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Differences in the dispersal of s-flatbacks released from Peak Island during neap and spring tides.
Impact of Multipath Reflections on the Performance of Indoor Visible Light Positioning Systems
Creators: name: Gu, Wenjun
name: Aminikashani, Mohammadreza
name: Kavehrad, Mohsen
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: Visible light communication (VLC) using light-emitting-diodes (LEDs) has been a popular research area recently. VLC can provide a practical solution for indoor positioning. In this paper, the impact of multipath reflections on indoor VLC positioning is investigated, considering a complex indoor environment with walls, floor and ceiling. For the proposed positioning system, an LED bulb is the transmitter and a photo-diode (PD) is the receiver to detect received signal strength (RSS) information. Combined deterministic and modified Monte Carlo (CDMMC) method is applied to compute the impulse response of the optical channel. Since power attenuation is applied to calculate the distance between the transmitter and receiver, the received power from each reflection order is analyzed. Finally, the positioning errors are estimated for all the locations over the room and compared with the previous works where no reflections considered. Three calibration approaches are proposed to decrease the effect of multipath reflections.
description: Journal paper, 10 pages, 21 figures. arXiv admin note: text overlap with arXiv:1504.01192
title: Enhancing the Security and Privacy of Full-Stack JavaScript Web Applications
Creators: name: Staicu, Cristian-Alexandru
Publisher: name: UNSPECIFIED
Year: 2020

description: Web applications are the most important gateway to the Internet. Billions of users are relying on them every day and trusting them with their most sensitive data. Therefore, ensuring the security and privacy of web applications is of paramount importance. Traditionally, the server-side code of websites was written in languages such as PHP or Java for which security issues are well studied and understood. Recently, however, full-stack JavaScript web applications emerged, which have both their client-side and server-side code written in this language. We hypothesize that there are several unique properties of full-stack JavaScript web applications that pose a serious challenge for the security analysts: the new threat model for JavaScript, the excessive code reuse, the prevalence of code transformations, and the existence of complex full-stack threats. In this dissertation, we support this thesis by performing several in-depth studies of the JavaScript ecosystem and by proposing multiple improvements to the state-of-the art practices. First, we discuss two types of security vulnerabilities that are aggravated by the new threat model: injections and regular-expression denial of service. Second, we show that excessive code reuse in the JavaScript ecosystem increases the chance of relying on malicious or vulnerable code. Third, we provide evidence that code transformations are widespread and that full-stack threats exist. Finally, we propose several improvements for techniques aimed at hardening web applications: cost-effective consideration of implicit flows, the extraction of taint specification for third-party libraries, and pragmatic program analysis for defending against injections. The problem of securing full-stack JavaScript web applications is far from settled, but we hope that the current dissertation serves as motivation for future work to consider this increasingly important class of applications. In particular, we argue for holistic approaches that consider full-stack and cross-library information flows.
Solutions of the Quantum Dynamical Yang-Baxter Equation and Dynamical Quantum Groups
Creators: name: Etingof, Pavel
name: Varchenko, Alexander
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: The quantum dynamical Yang-Baxter (QDYB) equation is a useful generalization of the quantum Yang-Baxter (QYB) equation. This generalization was introduced by Gervais, Neveu, and Felder. Unlike the QYB equation, the QDYB equation is not an algebraic but a difference equation, with respect to a matrix function rather than a matrix. The QDYB equation and its quasiclassical analogue (the classical dynamical Yang-Baxter equation) arise in several areas of mathematics and mathematical physics (conformal field theory, integrable systems, representation theory). The most interesting solution of the QDYB equation is the elliptic solution, discovered by Felder. In this paper, we prove the first classification results for solutions of the QDYB equation. These results are parallel to the classification of solutions of the classical dynamical Yang-Baxter equation, obtained in our previous paper. All solutions we found can be obtained from Felder’s elliptic solution by a limiting process and gauge transformations. Fifteen years ago the quantum Yang-Baxter equation gave rise to the theory of quantum groups. Namely, it turned out that the language of quantum groups (Hopf algebras) is the adequate algebraic language to talk about solutions of the quantum Yang-Baxter equation. In this paper we propose a similar language, originating from Felder’s ideas, which we found to be adequate for the dynamical Yang-Baxter equation. This is the language of dynamical quantum groups (or h-Hopf algebroids), which is the quantum counterpart of the language of dynamical Poisson groupoids, introduced in our previous paper.
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Year: 2024

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NIVELL DE SUFICIÈNCIA C1. CURS DE LLENGUA CATALANA. EDICIÓ 2017

 

Número de páginas: 458

Idioma: CATALÁN

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Overview

Llibre que segueix el programa del nivell de suficiència de català de la Secretaria de Política Lingüística de la Generalitat de Catalunya i de l'Institut d'Estudis Baleàrics del Govern de les Illes Balears. Estructurat en tres grans blocs: Comunicació, Estudi de la Llengua i Marc Sociolingüístic.
Figure S2. S-flatback distribution probabilities from Peak Island after (a) 3 days and (b) 120 days of passive drift (scenarios PD-TP-neap/spring) from Does behaviour affect the dispersal of flatback post-hatchlings in the Great Barrier Reef?
Creators: name: Wildermann, Natalie
name: Critchell, Kay
name: Fuentes, Mariana M. P. B.
name: Limpus, Colin
name: Wolanski, Eric
name: Hamann, Mark
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: 60302 Biogeography and Phylogeography
subject: FOS: Biological sciences
subject: 60801 Animal Behaviour
subject: 80110 Simulation and Modelling
subject: FOS: Computer and information sciences

description: Differences in the dispersal of s-flatbacks released from Peak Island during neap and spring tides.
(3428) Lamparus Baines
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
High Sensitivity Micro-Elastometry: Applications in Blood Coagulopathy
Creators: name: Wu, Gongting
name: Krebs, Charles R.
name: Wolberg, Alisa S.
name: Lin, Feng Chang
name: Oldenburg, Amy L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Highly sensitive methods for the assessment of clot structure can aid in our understanding of coagulation disorders and their risk factors. Rapid and simple clot diagnostic systems are also needed for directing treatment in a broad spectrum of cardiovascular diseases. Here we demonstrate a method for micro-elastometry, named Resonant Acoustic Spectroscopy with Optical Vibrometry (RASOV), which measures the clot elastic modulus (CEM) from the intrinsic resonant frequency of a clot inside a microwell. We observed a high correlation between the CEM of human blood measured by RASOV and a commercial Thromboelastograph (TEG), (R=0.966). Unlike TEG, RASOV requires only 150 μL of sample and offers improved repeatability. Since CEM is known to primarily depend upon fibrin content and network structure, we investigated the CEM of purified clots formed with varying amounts of fibrinogen and thrombin. We found that RASOV was sensitive to changes of fibrinogen content (0.5–6 mg/mL), as well as to the amount of fibrinogen converted to fibrin during clot formation. We then simulated plasma hypercoagulability via hyperfibrinogenemia by spiking whole blood to 150% and 200% of normal fibrinogen levels, and subsequently found that RASOV could detect hyperfibrinogenemia-induced changes in CEM and distinguish these conditions from normal blood.
The sh Lie Structure of Poisson Brackets in Field Theory
Creators: name: Stasheff, J.
name: Fulp, R.
name: Lada, T.
name: Barnich, G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1998

description: A general construction of an sh Lie algebra (L∞-algebra) from a homological resolution of a Lie algebra is given. It is applied to the space of local functionals equipped with a Poisson bracket, induced by a bracket for local functions along the lines suggested by Gel’fand, Dickey and Dorfman. In this way, higher order maps are constructed which combine to form an sh Lie algebra on the graded differential algebra of horizontal forms. The same construction applies for graded brackets in field theory such as the Batalin-Fradkin-Vilkovisky bracket of the Hamiltonian BRST theory or the Batalin-Vilkovisky antibracket.
Population synthesis of classical low-mass X-ray binaries in the Galactic Bulge
Creators: name: van Haaften, L. M.
name: Nelemans, G.
name: Voss, R.
name: van der Sluys, M. V.
name: Toonen, S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Aims. We model the present-day population of 'classical' low-mass X-ray binaries (LMXBs) with neutron star accretors, which have hydrogen-rich donor stars. Their population is compared with that of hydrogen-deficient LMXBs, known as ultracompact X-ray binaries (UCXBs). We model the observable LMXB population and compare it to observations. Methods. We combine the binary population synthesis code SeBa with detailed LMXB evolutionary tracks to model the size and properties of the present-day LMXB population in the Galactic Bulge. Whether sources are persistent or transient, and what their instantaneous X-ray luminosities are, is predicted using the thermal-viscous disk instability model. Results. We find a population of ~2.1 x 10^3 LMXBs with neutron star accretors. Of these about 15 - 40 are expected to be persistent (depending on model assumptions), with luminosities higher than 10^35 erg s^-1. About 7 - 20 transient sources are expected to be in outburst at any given time. Within a factor of two these numbers are consistent with the observed population of bright LMXBs in the Bulge. This gives credence to our prediction of the existence of a population of ~1.6 x 10^3 LMXBs with low donor masses that have gone through the period minimum, and have present-day mass transfer rates below 10^-11 Msun yr^-1. Conclusions. Even though the observed population of hydrogen-rich LMXBs in the Bulge is larger than the observed population of (hydrogen-deficient) UCXBs, the latter have a higher formation rate. While UCXBs may dominate the total LMXB population at the present, the majority would be very faint, or may have become detached and produced millisecond radio pulsars. In that case UCXBs would contribute significantly more to the formation of millisecond radio pulsars than hydrogen-rich LMXBs. [abridged]
description: 8 pages, 10 figures. Accepted for publication in Astronomy and Astrophysics. v2: minor language corrections
Recurrence criteria for generalized Dirichlet forms
Creators: name: Gim, Minjung
name: Trutnau, Gerald
Publisher: name: arXiv
Year: 2015
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics
subject: primary: 31C25, 47D07, 60G17, secondary: 60J60, 47B44, 60J35

description: We develop sufficient analytic conditions for recurrence and transience of non-sectorial perturbations of possibly non-symmetric Dirichlet forms on a general state space. These form an important subclass of generalized Dirichlet forms which were introduced in \cite{St1}. In case there exists an associated process, we show how the analytic conditions imply recurrence and transience in the classical probabilistic sense. As an application, we consider a generalized Dirichlet form given on a closed or open subset of $\mathbb{R}^d$ which is given as a divergence free first order perturbation of a non-symmetric energy form. Then using volume growth conditions of the sectorial and non-sectorial first order part, we derive an explicit criterion for recurrence. Moreover, we present concrete examples with applications to Muckenhoupt weights and counterexamples. The counterexamples show that the non-sectorial case differs qualitatively from the symmetric or non-symmetric sectorial case. Namely, we make the observation that one of the main criteria for recurrence in these cases fails to be true for generalized Dirichlet forms.
description: Revised version: in particular the whole Section 2.2 was revised as in all previous arXiv-versions it was by mistake the preliminary Section 2.2 before its final revision
Timing and Duration of Incarceration and High-Risk Sexual Partnerships Among African Americans in North Carolina
Creators: name: Khan, Maria R.
name: Schoenbach, Victor J.
name: Wohl, David A.
name: Kaufman, Jay S.
name: Miller, William C.
name: Weir, Sharon S.
name: Adimora, Adaora A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Incarceration may contribute to HIV transmission by disrupting stable partnerships and promoting high-risk partnerships. We investigated incarceration and high-risk partnerships among African Americans in North Carolina (NC).
Exchange Dynamical Quantum Groups
Creators: name: Etingof, Pavel
name: Varchenko, Alexander
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 1999

description: For any simple Lie algebra g and any complex number q which is not zero or a nontrivial root of unity, we construct a dynamical quantum group (Hopf algebroid), whose representation theory is essentially the same as the representation theory of the quantum group Uq(g ). This dynamical quantum group is obtained from the fusion and exchange relations between intertwining operators in representation theory of Uq(g ), and is an algebraic structure standing behind these relations.
Paired Comparison of Observed and Expected Coronary Heart Disease Rates over 12 Years from the Atherosclerosis Risk In Communities Study
Creators: name: Coresh, Josef
name: Folsom, Aaron R.
name: Rosamond, Wayne
name: Paynter, Nina P.
name: Louis, Thomas A.
name: Sharrett, A. Richey
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: To quantify the relationship between coronary heart disease (CHD) risk factor levels and changes over time and population-wide CHD morbidity and mortality.