cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Gravity can significantly modify classical and quantum Poincare recurrence theorems
Creators: name: Dong, Ruifeng
name: Stojkovic, Dejan
Publisher: name: arXiv
Year: 2016
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Poincare recurrence theorem states that any finite system will come arbitrary close to its initial state after some very long but finite time. At the statistical level, this by itself does not represent a paradox, but apparently violates the second law of thermodynamics, which may lead to some confusing conclusions for macroscopic systems. However, this statement does not take gravity into account. If two particles with a given center of mass energy come at the distance shorter than the Schwarzschild diameter apart, according to classical gravity they will form a black hole. In the classical case, a black hole once formed will always grow and effectively quench the Poincare recurrence. We derive the condition under which the classical black hole production rate is higher than the classical Poincare recurrence rate. In the quantum case, if the temperature of the black hole is lower than the temperature of the surrounding gas, such a black hole cannot disappear via Hawking evaporation. We derive the condition which gives us a critical temperature above which the black hole production is faster than quantum Poincare recurrence time. However, in quantum case, the quantum Poincare recurrence theorem can be applied to the black hole states too. The presence of the black hole can make the recurrence time longer or shorter, depending on whether the presence of the black hole increases or decreases the total entropy. We derive the temperature below which the produced black hole increases the entropy of the whole system (gas particles plus a black hole). Finally, if evolution of the system is fast enough, then newly formed black holes will merge and accrete particles until one large black hole dominates the system. We give the temperature above which the presence of black holes increase the entropy of the whole system and prolongs the Poincare recurrence time.
description: 10 pages, 1 figure. Minor modifications made
(200912) Eliza Kate Huckerby
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development.
Creators: name: Novellasdemunt, Laura
name: Kucharska, Anna
name: Baulies, Anna
name: Hutton, Colin
name: Vlachogiannis, Georgios
name: Repana, Dimitra
name: Rowan, Andrew
name: Suárez-Bonnet, A
name: Ciccarelli, Francesca
name: Valeri, Nicola
name: Li, Vivian SW
Publisher: name: The Francis Crick Institute
Year: 2023
Subjects: Developmental Biology
Human Biology & Physiology
Stem Cells
Signalling & Oncogenes
Tumour Biology

description: Adenomatous polyposis coli (APC) mutation is the hallmark of colorectal cancer (CRC), resulting in constitutive WNT activation. Despite decades of research, targeting WNT signaling in cancer remains challenging due to its on-target toxicity. We have previously shown that the deubiquitinating enzyme USP7 is a tumor-specific WNT activator in APC-truncated cells by deubiquitinating and stabilizing β-catenin, but its role in gut tumorigenesis is unknown. Here, we show in vivo that deletion of Usp7 in Apc-truncated mice inhibits crypt hyperproliferation and intestinal tumor development. Loss of Usp7 prolongs the survival of the sporadic intestinal tumor model. Genetic deletion, but not pharmacological inhibition, of Usp7 in Apc+/- intestine induces colitis and enteritis. USP7 inhibitor treatment suppresses growth of patient-derived cancer organoids carrying APC truncations in vitro and in xenografts. Our findings provide direct evidence that USP7 inhibition may offer a safe and efficacious tumor-specific therapy for both sporadic and germline APC-mutated CRC.
COVIDmeter
Creators: Statens Serum Institut
Publisher: name: Rigsarkivet
Year: 2024

description: Undersøgelse hvor frivillige ugentlig besvarede en række spørgsmål med formål at overvåge covidlignende symptomer i hele covid perioden mhp. afrapportering / offentliggørelse på SSI´s egen hjemmeside: tendenser, opadgående/nedadgående pandemi,
symptomer, kontaktflade, testrate og positivprocenten i covidtest, vaccinationsstatus.
Ugentlig rapportering til ECDC - European Center for Disease Control.
An electroweak basis for neutrinoless double $β$ decay
Creators: name: Graesser, Michael L.
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A discovery of neutrinoless double-$β$ decay would be profound, providing the first direct experimental evidence of $ΔL=2$ lepton number violating processes. While a natural explanation is provided by an effective Majorana neutrino mass, other new physics interpretations should be carefully evaluated. At low--energies such new physics could manifest itself in the form of color and $SU(2)_L \times U(1)_{Y}$ invariant higher dimension operators. Here we determine a complete set of electroweak invariant dimension--9 operators, and our analysis supersedes those that only impose $U(1)_{em}$ invariance. Imposing electroweak invariance implies: 1) a significantly reduced set of leading order operators compared to only imposing $U(1)_{em}$ invariance; and 2) other collider signatures. Prior to imposing electroweak invariance we find a minimal basis of 24 dimension-9 operators, which is reduced to 11 electroweak invariant operators at leading order in the expansion in the Higgs vacuum expectation value. We set up a systematic analysis of the hadronic realization of the 4-quark operators using chiral perturbation theory, and apply it to determine which of these operators have long-distance pion enhancements at leading order in the chiral expansion. We also find at dimension--11 and dimension--13 the electroweak invariant operators that after electroweak symmetry breaking produce the remaining $ΔL=2$ operators that would appear at dimension--9 if only $U(1)_{em}$ is imposed.
description: 31 pages, 6 tables, 1 figure. v3 updated references and added extended introduction, conclusions unchanged from v2. v4: updated references; final published version
Investigations of H-Mode Plasmas Triggered Directly by Pellet Injection in the DIII-D Tokamak
Creators: name: Baylor, L. R.
name: Burrell, K. H.
name: Carlstrom, T. N.
name: Gohil, P.
name: Jernigan, T. C.
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
Bag of Attributes for Video Event Retrieval
Creators: name: Duarte, Leonardo A.
name: Penatti, Otávio A. B.
name: Almeida, Jurandy
Publisher: name: arXiv
Year: 2016
Subjects: subject: Information Retrieval (cs.IR)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Computer and information sciences

description: In this paper, we present the Bag-of-Attributes (BoA) model for video representation aiming at video event retrieval. The BoA model is based on a semantic feature space for representing videos, resulting in high-level video feature vectors. For creating a semantic space, i.e., the attribute space, we can train a classifier using a labeled image dataset, obtaining a classification model that can be understood as a high-level codebook. This model is used to map low-level frame vectors into high-level vectors (e.g., classifier probability scores). Then, we apply pooling operations to the frame vectors to create the final bag of attributes for the video. In the BoA representation, each dimension corresponds to one category (or attribute) of the semantic space. Other interesting properties are: compactness, flexibility regarding the classifier, and ability to encode multiple semantic concepts in a single video representation. Our experiments considered the semantic space created by state-of-the-art convolutional neural networks pre-trained on 1000 object categories of ImageNet. Such deep neural networks were used to classify each video frame and then different coding strategies were used to encode the probability distribution from the softmax layer into a frame vector. Next, different pooling strategies were used to combine frame vectors in the BoA representation for a video. Results using BoA were comparable or superior to the baselines in the task of video event retrieval using the EVVE dataset, with the advantage of providing a much more compact representation.
Doxorubicin-based combination treatments to enhance antitumour effects and reduce cardiotoxicity
Creators: name: Rayner, David Michael
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the La Trobe Institute for Molecular Science, Faculty of Science, Health, and Engineering, La Trobe University, Bundoora.

Doxorubicin (DOX) is a chemotherapeutic agent clinically used against a wide range of solid and blood neoplasms. However the cumulative lifetime dose of DOX is limited by dose-dependent cardiotoxicity. A drug treatment combination of DOX and the formaldehyde-releasing prodrug AN7 exhibits cardioprotection, while maintaining antitumour efficacy. The present study investigated the response of breast cancer and cardiomyocyte cell lines to DOX/AN7 combination treatments in vitro, in terms of the formation of DOX-DNA covalent adducts and the effect adduct levels had on cell death. The cell lines encompassed a range of species; human, mouse and rat. High throughput gene expression analyses were conducted in cardiomyocyte and breast cancer cells in vitro to identify pathways involved in adduct response in cells. Cardiac effects of DOX/AN7 were also assessed in mice, employing damage markers and ultrastructural changes at 72 hours after acute DOX treatment. Gene expression levels were also assessed in ventricles of treated mice to investigate pathways or biomarkers associated with cardiac damage or cardioprotection. In the in vitro studies it was apparent that higher levels of adducts formed in cardiomyocyte compared to breast cancer cells. Adducts were associated with increased mitochondrial dysfunction and cell death in the breast cancer cells, while adducts in cardiomyocyte cells exhibited no mitochondrial dysfunction nor increase in cell death. Mice treated with the DOX/AN7 combination showed reduced plasma levels of cardiac troponinT compared to DOX alone. Furthermore, these mice displayed amelioration of DOX-induced ultrastructural disorganization in electron microscope analysis of heart ventricle sections. Preliminary gene expression analyses indicated that DOX/AN7 cardioprotection was associated with a p53-independent induction of p21, corresponding Sirt1 up-regulation, and increase in expression of mitochondrial biogenesis factor PGC1α. The results of this study indicate the addition of AN7 alters the response of cardiomyocytes to DOX while enhancing its anticancer efficacy in vitro. The whole organ protection of DOX/AN7 in vivo opens the possibility for similar formaldehyde-releasing drugs to be used in combination with DOX to reduce dose-dependent cardiotoxicity, making DOX a far more valuable clinical tool in breast cancer regimes.
Kerr effect from diffractive skew scattering in chiral $p_x \pm i p_y$ superconductors
Creators: name: König, Elio J.
name: Levchenko, Alex
Publisher: name: arXiv
Year: 2016
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We calculate the temperature dependent anomalous ac Hall conductance $σ_H(Ω, T)$ for a two-dimensional chiral p-wave superconductor. This quantity determines the polar Kerr effect, as it was observed in Sr$_2$RuO$_4$ [J. Xia $et$ $al.$, Phys. Rev. Lett. 97, 167002 (2006)]. We concentrate on a single band model with arbitrary isotropic dispersion relation subjected to rare, weak impurities treated in the Born approximation. As we explicitly show by detailed computation, previously omitted contributions to extrinsic part of an anomalous Hall response, physically originating from diffractive skew scattering on quantum impurity complexes, appear to the leading order in impurity concentration. By direct comparison with published results from the literature we demonstrate the relevance of our findings for the interpretation of the Kerr effect measurements in superconductors.
description: 5 pages, 2 figures; Supplementary material included
Aging of the Zero-Field-Cooled Magnetization in Ising Spin Glasses: Experiment and Numerical Simulation
Creators: name: Bernardi, Lorenzo W.
name: Hukushima, Koji
name: Ito, Atsuko
name: Takayama, Hajime
name: Tobo, Aya
name: Yoshino, Hajime
Publisher: name: The American Physical Society
Year: 2001
Subjects: subject: 530

description: Physical Review Letters
Jernbanetransport
Creators: Danmarks Statistik
Publisher: name: Rigsarkivet
Year: 2024

description: Statistikken Jernbanetransport belyser investeringer i jernbaneanlæg, dvs. skinner og servicebygninger og lignende, samt rullende materiel (lokomotiver og vogne mv.), trafik på jernbanenettet, ulykker og transport af gods- og passagerer med tog.
(200907) George Wilcox Huckerby
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Social Action to Combat Human Trafficking
Creators: name: Honeyman, Katherine
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Clinical Psychology to the School of Psychology and Public Health, College of Science, Health, and Engineering, La Trobe University, Bundoora.

Human trafficking (HT), today’s equivalent of slavery, involves severe violations of human rights. While the majority of people might perceive, or believe, this global phenomenon to be wrong and inhumane, the belief does not appear to lead to a willingness to take action to stop the problem (UNODC, 2008). The aim of this research was to synthesise past theoretical approaches and empirical studies to understand better the failure to engage with changes needed to end HT. Across three studies, this research sought to understand Australians’ attitudes and emotional reactions to victims of HT, and to explore factors that might influence engagement in social action to combat this international problem. With insights gathered from the Australian community (Study 1), we experimentally manipulated factors that might possibly influence willingness to engage in social action, such as perspective-taking and beliefs about efficacy (Study 2) and participants’ perceptions of a victim’s responsibility for the problem of sex trafficking as well as responsibility for the solution (Study 3). Across the three studies we consistently found a strong correlation between personal distress and willingness to act. Distress (but not empathy) mediated the relationship between gender and willingness to engage in social action, which showed that women were more willing than men to combat HT. Taking the perspective of the victim did not have any significant effects on willingness to act. Victims who were presented as having control over their entry into sex trafficking were judged negatively and evoked less empathy and distress, leading participants to be less willing to engage in social action. Throughout this thesis, we discuss further results and the implications for promoting social action, canvassing ways to encourage societal change in order to counter the oppression of human beings.
title: Bayes methods in group sequential clinical trials
Creators: name: Qian, Wendi
Publisher: name: University of Kent
Year: 2022

description: Bayesian methods for group sequential clinical trials have received increasing at­tention recently. They offer an approach for dealing with many difficult problems and have some practical advantages over frequentist methods. This thesis covers Bayesian methods for group sequential clinical trials comparing two treatments using both the Bayes sequential procedure and the Bayes sequential decision pro­cedure. The main outcome measures for clinical trials are distributed as normal, binomial, and exponential and the proportional hazard model for survival time data. Under the framework of Bayes sequential procedure for group sequential clini­cal trials, the student t prior distribution for the parameter of interest is proposed as a replacement for the normal prior distribution when the sample mean is very distant from the mean of the prior distribution. The framework of Bayes sequen­tial procedure in clinical trials on normal distribution responses with variance unknown is given. Bayes sequential decision theory is applied to group sequential clinical trials. First, Bayes sequential decision procedures with piecewise continuous loss func­tions are used in clinical trials on normal distribution responses. The procedures with loss functions which consider treatment efficacy and patient horizon are then given in clinical trials on binary responses. Approximation methods of Bayes sequential decision procedures are explored in clinical trials with survival time data. Robust Bayes analysis in clinical trials is presented to address the criticism on the subjective prior distribution for parameters of interest.
(200910) Sarah Huckerby
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
The Bartnik-Bray outer mass of small metric spheres in time-symmetric 3-slices
Creators: name: Wiygul, David
Publisher: name: arXiv
Year: 2016
Subjects: subject: Differential Geometry (math.DG)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: Given a sphere with Bartnik data close to that of a round sphere in Euclidean 3-space, we compute its Bartnik-Bray outer mass to first order in the data's deviation from the standard sphere. The Hawking mass gives a well-known lower bound, and an upper bound is obtained by estimating the mass of a static vacuum extension. As an application we confirm that in a time-symmetric slice concentric geodesic balls shrinking to a point have mass-to-volume ratio converging to the energy density at their center, in accord with physical expectation and the behavior of other quasilocal masses. For balls shrinking to a flat point we can also compute the outer mass to fifth order in the radius---the term is proportional to the Laplacian of the scalar curvature at the center---but our estimate is not refined enough to identify this term at a point which is merely scalar flat. In particular it cannot discern gravitational contributions to the mass.
description: The final version will appear in Communications in Mathematical Physics
title: Ranging behaviour and seasonal movements of Sumatran orangutans (Pongo pygmaeus abelii) in swamp forests
Creators: name: Singleton, Ian
Publisher: name: University of Kent
Year: 2022

description: The ranging behaviour of Sumatran orangutans was studied in a swamp forest within the Leuser Ecosystem, Sumatra, Indonesia. The use of line transect techniques for estimating orangutan densities from nests was also examined. The densities obtained, in conjunction with raw numbers of new nests along transects were then compared with estimates of forest productivity in an attempt to identify how orangutan movements are influenced by resource availability. Using nests as an indicator of orangutan numbers produced serious underestimates of absolute densities for a variety of reasons. These were considered to stem mostly from the use of decay rates estimated from total time to nest disappearance, whilst under­detecting older nests in censuses, and from the difficulties of detecting nests on or above transects and accurately estimating distances. The number of new nests along a transect was still considered a reliable indicator of fluctuations in absolute densities. Orangutan home ranges at Suaq Balimbing were found to be distinctly larger than previously reported elsewhere. Females appear to utilise core areas of at least 500 ha, whilst also using a peripheral excursion zone so that total home ranges probably lie between 900 ha and 1500 ha. Adult male and subadult male ranges were considered to be in excess of 3000 ha and perhaps as much as 10000 ha. There was no evidence that adult females or adult males need necessarily be transient or nomadic as previously proposed. Subadult males, however, may constitute a dispersal phase. Orangutan movements were related to fruit availability, in that they will move to areas where fruit is abundant, but also into other areas when fruit is generally scarce. Thus there was evidence that orangutans shift diets during lean periods rather than travelling large distances. There was no evidence to support the occurrence of large-scale seasonal movements of orangutans. There was evidence to suggest that dominant adult males behave differently to other, non-dominant males, in that they occupy smaller ranges, probably as a result of being able to restrict access by other males to receptive females. Non-dominant adult males tended to avoid the dominant male, whereas subadult males did not. Evidence was also found to support the existence of clusters of females with similar ranges, who may be related, preferentially associate with each other, and are to some degree synchronised reproductively.
Not at the table but stuck paying the bill: perceptions of injustice in China’s Xin’anjiang ecocompensation program
Creators: name: Jiang, Xinhui
name: Eaton, Sarah
name: Kostka, Genia
Publisher: name: Humboldt-Universität zu Berlin
Year: 2021
Subjects: subject: eco-compensation
subject: environmental politics
subject: PES
subject: environmental justice
subject: China
subject: 333.7 Landflächen, Naturräume für Freizeit und Erholung, Naturreservate, Energie

description: A growing body of research highlights the decisive role that justice claims play in creating sustainable payment for ecosystem services (PES) programs. Employing Sikor et al.’s approach to the study of justice claims in ecosystem governance along three dimensions—distribution, procedure and recognition—we study the negotiation process behind China’s flagship interprovincial PES agreement: the Xin’anjiang River eco-compensation agreement between Huangshan (Anhui province) and Hangzhou (Zhejiang province) prefectures. We find that divergent claims between stakeholders on matters of distributive and procedural justice undercut one party’s commitment to the agreement. Local officials in the upstream locality (Huangshan) see themselves as having been disadvantaged in both procedural and distributive aspects of negotiation. They claim to have been insufficiently included in a bargaining process that involved not only the downstream locality (Hangzhou) but also the central government. Huangshan stakeholders also see themselves as largely excluded from the benefits of cleaner water and bearing too much of the pollution abatement cost. For their part, Hangzhou stakeholders have advanced a ‘polluters pay’ view of distributive justice and found partial support for this claim from Beijing. Our findings suggest that attending to environmental justice considerations should be given top priority in China’s design of PES schemes.
Improved Bounds on Sidon Sets via Lattice Packings of Simplices
Creators: name: Kovačević, Mladen
name: Tan, Vincent Y. F.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Combinatorics (math.CO)
subject: Computational Geometry (cs.CG)
subject: Information Theory (cs.IT)
subject: Group Theory (math.GR)
subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences
subject: 05B10, 05B40, 11B13, 11B75, 11B83, 11H31, 52C17, 94B65, 20K99

description: A $ B_h $ set (or Sidon set of order $ h $) in an Abelian group $ G $ is any subset $ \{b_0, b_1, \ldots,b_{n}\} $ of $ G $ with the property that all the sums $ b_{i_1} + \cdots + b_{i_h} $ are different up to the order of the summands. Let $ ϕ(h,n) $ denote the order of the smallest Abelian group containing a $ B_h $ set of cardinality $ n + 1 $. It is shown that \[ \lim_{h \to \infty} \frac{ ϕ(h,n) }{ h^n } = \frac{1}{n! δ_L(\triangle^n)} , \] where $ δ_L(\triangle^n) $ is the lattice packing density of an $ n $-simplex in Euclidean space. This determines the asymptotics exactly in cases where this density is known ($ n \leq 3 $) and gives improved bounds on $ ϕ(h,n) $ in the remaining cases. The corresponding geometric characterization of bases of order $ h $ in finite Abelian groups in terms of lattice coverings by simplices is also given.
description: 9 pages, 2 figures
Welche Einstellungen haben Lehrende zur Lehre?
Creators: name: Funger, Anna
name: Kamphans, Marion
Publisher: name: Hochschuldidaktisches Zentrum der Technischen Universität Dortmund
Year: 2009
Subjects: subject: 370

description: Journal Hochschuldidaktik ; 20. Jahrgang 2009 Heft 1
The Inventory of Personality Organization: A valid instrument to detect the severity of personality dysfunction
Creators: name: Unoka, Zsolt
name: Csáky-Pallavicini, Krisztina
name: Horváth, Zsolt
name: Demetrovics, Zsolt
name: Maraz, Aniko
Publisher: name: Humboldt-Universität zu Berlin
Year: 2022
Subjects: subject: personality functioning
subject: personality impairment
subject: personality disorganization
subject: personality disorders
subject: assessment
subject: Inventory of Personality Organization
subject: 150 Psychologie

description: Background and aims In the eleventh revision of the International Classification of Diseases (ICD-11), the severity of personality dysfunction became the central dimension of personality disorder’s (PDs) definition, besides the trait domain qualifiers. Personality functioning, also known as personality organization (PO), is becoming an increasingly important concept in administering, predicting, and measuring severity and nature of personality disturbance. Otto Kernberg and his team developed several tools to measure personality impairment. The Inventory of Personality Organization (IPO) is a self-report rating scale for the measurement of PO. Aim of this study was to identify severity groups according to the level of PO and to explore their validity. Materials and methods A clinical sample of 118 patients was recruited from a 4-weeks in-patient cognitive psychotherapy program. Beside the IPO, Structured Clinical Interview for the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, (DSM-IV.) Axis I and II, Symptom Check List-90 (SCL-90), State-Trait Anger Expression Inventory and Dissociative Experience scale (DES). Two types of analyses were conducted: a person-centered (latent profile) analysis and various variable-centered tests to confirm the factor structure of IPO and calculate group differences. Results The three-factor (CFI = 0.990, TLI = 0.990, RMSEA = 0.022, SRMR = 0.089) and the five-factor (CFI = 0.995, TLI = 0.995, RMSEA = 0.014, SRMR = 0.090) models of the IPO was supported. Latent class analysis identified three subgroups of PO: “Well-integrated,” “Moderately integrated,” and “Disintegrated” classes. There were no significant differences between the three classes in the number of Axis 1 diagnoses (p = 0.354; η2 = 0.01). Group differences in the number of PDs, the number of PD symptoms as well as in the presence of borderline and depressive PD were significant (all p < 0.001; V = 0.35–0.42; η2 = 0.15–0.26). Persons with more severe PO problem level had higher rates of psychopathological symptoms, state and trait anger, and dissociative characteristics (all p < 0.001; η2 = 0.13–0.36). Conclusion The IPO can be an appropriate instrument to measure the severity of personality disorganization and to classify participants along a continuum of severity in this regard. Our results present further evidence that the severity of personality dysfunction, the central dimension of the ICD-11 and the Alternative Model for PDs is detectable with an instrument, the IPO, that was initially developed to detect the disturbances in PO.
(200908) Sarah Standing
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Μελέτη των ασπίδων κολλαγόνου σε οφθαλμολογικές εφαρμογές στην Βιοχαρτική μηχανική
Creators: name: Αρβανιτίδης, Γεώργιος Νικολάου
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Ασπίδες Κολλαγόνου
Κολλαγονό
Οφθαλμολογία
Corneal shields
Collagen
Ophthalmology

description: Οι ασπίδες του κολλαγόνου έχουν αναδειχθεί ως μια πολλά υποσχόμενη θεραπευτική ιατρική συσκευή για την θεραπεία του κερατοειδούς, καθώς μπορούν να υποστηρίξουν την κυτταρική ανάπτυξη και την αναγέννηση των ιστών καθώς και ελεγχόμενη απελευθέρωση βιοδραστικών ουσιών για θεραπευτικές εφαρμογές. Το επίκεντρο αυτής της μελέτης είναι η εξερεύνηση της κατασκευής θεραπευτικών ασπίδων κερατοειδούς από κολλαγόνο χρησιμοποιώντας τρισδιάστατα εκτυπωμένα καλούπια. Οι ασπίδες κατασκευάζονται με διασύνδεση αλυσίδων κολλαγόνου. Διενεργείται δοκιμή in vitro ώστε να διερευνηθεί η ικανότητα της ασπίδας να δρα ως φορέας αντιβιοτικών, καθώς και η ικανότητα αποικοδόμησής τους. Χρησιμοποιούνται μέθοδοι συμπληρωματικού χαρακτηρισμού για την ανάλυση των ιδιοτήτων των ασπίδων κερατοειδούς και παρέχουν πληροφορίες για την πιθανή χρήση τους ως ιατροτεχνολογικά προϊόντα. Διά μέσου αυτών των μελετών, αποδεικνύεται ότι τα τρισδιάστατα εκτυπωμένα καλούπια μπορούν να χρησιμοποιηθούν για την παραγωγή ασπίδων κολλαγόνου κερατοειδούς με επιθυμητές ιδιότητες για κλινικές εφαρμογές. Επιπλέον, τα αποτελέσματα από τις in vitro τεχνικές δοκιμών και χαρακτηρισμού παρέχουν τη βάση για περαιτέρω έρευνα και ανάπτυξη στον τομέα των βιοϊατρικών συσκευών και της μηχανικής ιστών. Συνολικά, η μελέτη μας παρέχει πολύτιμες γνώσεις για την παραγωγή και τον χαρακτηρισμό των ασπίδων κολλαγόνου κερατοειδούς, που μπορεί να ανοίξουν το δρόμο για την ανάπτυξη νέων και βελτιωμένων θεραπειών του κερατοειδούς.
description: Corneal shields have emerged as a promising therapeutic medical device for corneal treatment, as they can support cell growth and tissue regeneration as well as controlled release of bioactive substances for therapeutic applications. The focus of this thesis is the exploration of fabrication of therapeutic collagen corneal shields using 3D printed molds. The shields are fabricated by crosslinking of collagen chains. In vitro testing is conducted to investigate the shield’s ability to act as an antibiotic carrier, as well as their degradability. Complementary characterization methods are employed to analyze the properties of the corneal shields and provide insights into their potential use as medical devices. Through these studies, it is demonstrated that 3D printed molds can be used to manufacture collagen corneal shields with desirable properties for clinical applications. Furthermore, the results from in vitro testing and characterization techniques provide a foundation for further research and development in the field of biomedical devices and tissue engineering. Overall, our study provides valuable insights into the manufacturing and characterization of collagen corneal shields, which may pave the way for the development of new and improved corneal therapies.
Expression patterns of the intracellular ion exchangers AtNHX5 and AtNHX6 and their role in subcellular trafficking to the vacuole
Creators: name: Ernest, Joanne
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Animal, Plant and Soil Science, School of Life Sciences, College of Science, Health and Engineering, AgriBio, the Centre for Agribiosciences, La Trobe University, Bundoora.

The family of sodium-hydrogen exchangers (NHX) are highly conserved across all taxa and function in cellular homeostasis via the antiport of a monovalent metal ion (Na+/K+/Li+) for a proton (H+) across a membrane. A sub-group of NHX proteins which localise to internal membranes have a role in lysosome or vacuolar trafficking and pH regulation in animal, plant and yeast cells, and are implicated in important human pathophysiological and neurological diseases. In plants and fungi, these antiporters are also important determinants of salt tolerance. The Arabidopsis thaliana intracellular sodium-proton antiporters NHX5 and NHX6 have a well-documented role in plant development, and have been used to improve salt tolerance in a variety of species. Recent evidence suggests that intracellular NHX proteins provide a “proton leak” to finely regulate the pH of intracellular compartments, and that maintenance of this pH is critical for vacuolar trafficking of soluble cargo. However, the expression patterns and regulatory elements of these antiporters, as well as their impacts on other subcellular trafficking machinery and processing enzymes, are largely unknown. This thesis first describes the investigation of the whole plant expression patterns of NHX5 and NHX6 using quantitative PCR and a promoter:GUS reporter construct. Secondly, the role of NHX5 and NHX6 in the processing of the predominant seed storage proteins (SSPs) and the impact on other members of the SSP processing and trafficking pathways is investigated. HPLC-MS and complimentary proteomic approaches were used to investigate the processing and accumulation of SSPs and the associated processing enzymes in the nhx5 nhx6 double mutant. Finally, the suite of known mis-trafficked vacuolar cargo was expanded using a novel methodology for identifying secreted proteins, and a bioinformatics comparison was conducted to identify common sorting determinants or other features.
Deformation and Ductile Fracture of a Low Alloy Steel under High Strain Rate Loading
Creators: name: Abdel-Malek, S.
name: Meyer, L. M.
Publisher: name: Institut für Umformtechnik - Technische Universität Dortmund
Year: 2006
Subjects: subject: ductile failure
subject: high plastic deformation
subject: high strain rate
subject: 620
subject: 670

description: Ductile failure of metals always occurs after a specific amount of plastic deformation. Therefore, the investigation and characterization of the deformation behaviour is required to understand the damage process and to describe the failure by a suitable constitutive relation. The effects of temperature and strain rate on the mechanical properties are important for the description of the material behavior in many applications. The MTS model is used here to describe the material behavior of some low alloy steels in a wide range of temperature and strain rates. A new part of stress is added to the MTS model in order to consider the effect of the dynamic strain aging at low strain rate and high temperature. The determination of material data at high strain and high strain rate is needed to describe the real material behaviour, specially for the simulation of high deformation and fracture. A special technique is used here to stop the deformation of tension specimen at high strain rate in the necking zone to determine the true stress and true strain. Using FEM computations (LS-DYNA 3D), the stress triaxiality in the necking zone of a tensile specimen is calculated up to the crack initiation. It is shown that the strain hardening characteristics affect the development of stress triaxiality.
title:   INVESTIGATION INTO, & ANALYSIS OF TEMPERATURE & STRAIN DATA FOR COAL MINE SEAL MATERIAL DURING CURING
Creators: name: van den Berg, Stephanus Jaco
Publisher: name: University of Kentucky Libraries
Year: 2022
Subjects: subject: FOS: Environmental engineering
valueUri: http://www.oecd.org/science/inno/38235147.pdf

description: On Monday, January 2, 2006, an underground explosion occurred at the Sago Mine WV, resulting in the death of 12 miners and seriously injury to one miner. On Saturday, May 20, 2006, an underground explosion occurred at the Darby Mine No.1 KY, resulting in five miner’s deaths and one miner’s injury.

The explosion of methane gas and coal dust result in many fatalities in the coal mining industry.

The coal mining industry uses mine seals to optimize the ventilation network. Those structures are designed not only to direct the air appropriately, but also, they should be capable of withstanding some levels of dynamic pressures given the occurrence of a methane or coal dust explosion. One fundamental assumption in the analysis of mine seals is that the seal materials (especially for those using concrete or pumpable materials) are continuous and homogeneous solids. In most cementitious materials, during the curing process of the mixture, an exothermic reaction is generated (hydration). The heat produced by the cementitious material during the initial mix, pour, and curing is called heat of hydration. The hydration process, in some cases, causes shrinkage of the mixture, which could generate cracks, fissures, and fractures over the initial curing phase. This phenomenon could weaken the seal or influence its structural integrity.

To date, there is not a study to assess the effects of the hydration process in the possible generation of micro-or-macro-fractures of mine seals. This thesis shows all information collected, processed, assessed, and analyzed during the curing process of these cementitious materials used for mine seals (Visual Inspections, Temperature, Strain, Acoustic Emissions (AE), Ground Penetration Radar (GPR), and Tracer Gas), and attempts to assess the relationship between those parameters and the possible formation of micro-cracks if any in the mine seals.
description: © 2022 Stephanus Jaco van den Berg
Materiality and Architecture in the Novels of Virginia Woolf
Creators: name: GRANT, CLAIRE JOYCE
Publisher: name: Monash University
Year: 2022
Subjects: Literary studies not elsewhere classified

description: This thesis addresses the influence of built structures on our interpretation of the world. This project concerns architecture and the built environment in the novels of Virginia Woolf. The aim of the research is to investigate the architectural settings and spaces evoked through description in the narrative. I study the places Virginia Woolf writes about and show how the narrative is evoked through the built environment, as well as objects contained therein. In this project, I assert that architecture and narrative reinforce one another. From this premise, I ask wider questions concerning the relationship between Woolf’s literary encounters with the built environment. I examine the theorisation of architecture and endeavour to contextualise it via Woolf’s architectural areas, street structures, non-domestic and domestic buildings.
Zeros in the magic neutrino mass matrix
Creators: name: Gautam, Radha Raman
name: Kumar, Sanjeev
Publisher: name: arXiv
Year: 2016
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the phenomenological implications of the presence of two zeros in a magic neutrino mass matrix. We find that only two such patterns of the neutrino mass matrix are experimentally acceptable. We express all the neutrino observables as functions of one unknown phase $ϕ$ and two known parameters $Δm^{2}_{12}$, $r=Δm^{2}_{12}/Δm^{2}_{23}$. In particular, we find $\sin^2 θ_{13}=(2/3)r/(1+r)$. We also present a mass model for the allowed textures based upon the group $A_{4}$ using type I+II see-saw mechanism.
description: 9 pages, 3 figures, minor changes as reported in Erratum: Zeros in the magic neutrino mass matrix [Phys. Rev. D 94, 036004 (2016)] (some typographical errors in two equations and a table corrected, results and conclusions unaffected)
Design, Construction, and Applications of the Uniform Pressure Electromagnetic Actuator
Creators: name: Bradley, J.
name: Cheng, V.
name: Daehn, G. S.
name: Hatkevich, S.
name: Kamal, M.
Publisher: name: Institut für Umformtechnik - Technische Universität Dortmund
Year: 2006
Subjects: subject: high velocity forming
subject: sheet metal forming
subject: 620
subject: 670

description: High velocity forming can lead to better formability along with additional benefits. The spatial distribution of forming pressure in electromagnetic forming can be controlled by the configuration of the actuator. A new type of actuator is discussed which gives a uniform pressure distribution in forming. It also provides a mechanically robust design and has a high efficiency for flat sheet forming. Key quantitative concepts are presented that help in the design of the system. Examples of uses of the actuator are then presented, specifically with regard to forming shapes and surface embossing. This paper emphasizes the approaches and engineering calculations required to effectively use this actuator.
Embedding large graphs into a random graph
Creators: name: Ferber, Asaf
name: Luh, Kyle
name: Nguyen, Oanh
Publisher: name: arXiv
Year: 2016
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 05C80

description: In this paper we consider the problem of embedding almost-spanning, bounded degree graphs in a random graph. In particular, let $Δ\geq 5$, $\varepsilon > 0$ and let $H$ be a graph on $(1-\varepsilon)n$ vertices and with maximum degree $Δ$. We show that a random graph $G_{n,p}$ with high probability contains a copy of $H$, provided that $p\gg (n^{-1}\log^{1/Δ}n)^{2/(Δ+1)}$. Our assumption on $p$ is optimal up to the $polylog$ factor. We note that this $polylog$ term matches the conjectured threshold for the spanning case.
description: Incorporated referee comments. To appear in Bulletin of the London Mathematical Society
title: Attempted suicide and self injury in prisons : an exploration of risk factors and motivations
Creators: name: Snow, Louisa Claire
Publisher: name: University of Kent
Year: 2022

description: This research aims to develop a theoretical understanding of prisoners’ motivations for attempting suicide or injuring themselves without suicidal intent. The research proposes that whilst there are some similarities between the behaviours (i.e., both are self-directed and both result in physical harm) the differences between them outweigh their similarities. Most fundamentally, they are seen to differ in psychological, cognitive, motivational and functional respects. The research attempts to overcome limitations of previous studies, by providing a qualitative and quantitative analysis of first-hand prisoner accounts, focusing on their explanations for their behaviours. The research has three broad aims: 1. To examine what motivates or underlies attempted suicide/self-injury; 2. To explore the relationship between these behaviours and previously-identified risk factors; 3. To identify differences and similarities (in motivation and identified ‘risk’ factors) between different types of prisoners and different degrees of ‘suicidal’ behaviour. In-depth interviews with 143 prisoners in ten prisons were conducted. The sample was broadly balanced according to sex, age and behaviour. The interviews explored a range of issues, e.g., personal background histories, social support networks and self reported feelings before and after the incident. Data were analysed using qualitative and quantitative techniques to explore the underlying structures of risk and motivation, in addition to between-group differences. The research shows that prisoners who attempt suicide and those who injure themselves for other reasons share many similarities in terms of background, socio-demographic, psychiatric and criminal characteristics. However, the research has provided support for the proposition that these distinct behaviours are underpinned by fundamentally different motivations; they are precipitated by different emotions and serve different functions. These findings are drawn together into a Dual Path Model, indicating the different psychological routes to these behaviours. The implications, in terms of understanding these behaviours and in their broad management, are discussed.