cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
«Mit Sockenpuppen unterwegs»: Interkulturelles Figurenspiel im Partnerschaftsprojekt Nord-Süd
Creators: name: Amstad, Sabine
name: Lubos, Christiane
name: Schuh, Claudia
Publisher: name: Pestalozzianum
Year: 2012
Subjects: subject: Ästhetische Bildung in der Eingangsstufe
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Das Partnerschaftsprojekt der Pädagogischen Hochschule der FHNW mit der Universität Luigj Gurakuqi (in Shkodra, Nordalbanien) beinhaltet einen kulturellen, fachpädagogischen und auch persönlichen Austausch zwischen Menschen aus beiden Institutionen. Kern des Partnerschaftsprojekts mit Albanien ist ein gemeinsames kreatives Projekt. Zusammen mit unseren Albanischen Partnern gestalteten wir Workshops zum "interkulturellen Figurenspiel" in der Schweiz (Solothurn, 2009) und in Albanien (Shkodra, 2010).
title: British Theatre Scenography: The Reification of Spectacle
Creators: name: White, Christine A.
Publisher: name: Goldsmiths, University of London
Year: 1998

description: Over the last twenty years, the nature of theatre has changed due to the economic system of production which has led to the use of scenography to advertise the theatre product. Theatre has tried to make itself more attractive in the market place, using whatever techniques available. The technological developments of recent years have enabled the repackaging and sale of theatre productions both nationally and internationally. As a result theatre has become more 'designed' in an attempt to make it an attractive commodity. Scenography has become more prominent and this has changed the authorship of the theatre production, the dramatic text; the experts required by the new technologies have had a different involvement with the product, as they have actively contributed to the scenic image presented. Commercial values may have improved the integrity of theatre design and raised its profile within the profession, with theatre critics and with the academic world but it has proved unable to sell a production, which is ultimately lacking in theatricality and true spectacle. On particular occasions the gratuitous use of technology has been criticised, and as such, has been referred to as 'spectacle'. However, spectacle theatre does not simply mean theatre which uses technology, and so it has become imperative for the word spectacle to be more specifically applied, when used as a critical term to describe a form of theatre production. In this thesis, I intend to look at the significant factors that have led to the types of theatre presented in the last twenty years; to discuss these types of theatre in terms of their means of production and delivery to an audience, and to relate the change in scenographic values with a change in economic values; a change which has particularly affected the means of production, and as such is a vital beginning for any discussion of the scenography of the late twentieth century.
Üben als Prozess. Practice as Process
Creators: name: Amstad, Sabine
Publisher: name: Dr. Kovac
Year: 2015
Subjects: subject: 370 - Erziehung, Schul- und Bildungswesen

description: Der Artikel beleuchtet die vielgestaltigen Umstände und Prozesse des künstlerischen Übens. Er vertieft den Workshop zur Experimentellen Praxis und ihrer Reflexion. Experimental Practice and its Reflection, den Sabine Amstad anlässlich der Internationalen Tagung Begegnungen zwischen Kunst, Philosophie und Wissenschaft. Encounters between Art, Philosophy and Science vom 16.-17.4.2014 am Institut für Gestaltungspraxis und Kunstwissenschaft an der Leibniz Universität Hannover leitete.
MPEC 2025-H190 : 2025 HP6
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2025 HP6

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Bringing the Canadian Archive of Women in STEM to Wikidata: How wikidata can be used in an archival context
Creators: name: Lee, Yoo Young
name: Lemus-Rojas, Mairelys
name: Bokovay, Marina
Publisher: name: Zenodo
Year: 2020
Subjects: Wikidata
Archives
Women in STEM
Linked data

description: ACA 2020 Virtual Workshop Libraries and archives can play a critical role in the creation and curation of data in Wikidata to ensure underrepresented communities are not only included, but also properly described in the knowledge base. This workshop will provide a brief overview of Wikidata in the archival context and its possible uses. We will also share our experiences using wikidata for the the Canadian Archive of Women in STEM initiative (https://biblio.uottawa.ca/en/women-in-stem/about) based on the WikiProject Archival Description initiative (https://www.wikidata.org/wiki/Wikidata:WikiProject_Archival_Description). The goal of the Canadian Archive of Women in STEM is to bring attention to and promote the discovery of the archival records of women in STEM held by Canadian institutions–a bilingual portal containing descriptive metadata, a biographical sketch/admin history about the women/organizations and information about the host institution–in order to provide a simplified avenue for researchers to discover all available holdings. Contributing the archival metadata and the biographical sketch, as well as links to the host institutions to Wikidata could further increase the visibility of collections, finding aids, as well as the institutions themselves, beyond archival or library systems. This workshop is designed to be interactive with a series of hands-on activities which includes a demonstration of how to contribute content from archival finding aids to Wikidata as well as an introduction on efficient workflows and useful tools for contributing, visualizing and querying the data. This workshop aims to encourage archivists to participate in the open knowledge movement and contribute their unique collections to Wikidata to expand their findability and reach.
3094904.pdf
Creators: name: Wu, Shao-Hua
name: Chen, Mingkun
name: Barako, Michael
name: Jankovic, Vladan
name: hon, philip
name: Sweatlock, Luke
name: Povinelli, Michelle
Publisher: name: Optica Publishing Group
Year: 2017
Subjects: Uncategorized

description: Supplementary Information
title: De la violence à la révolte féministe
title: l’image de la femme vue par les auteurs masculins de la littérature noire africaine d’expression française des décennies pré et post indépendances
titleType: Subtitle
Creators: name: Gamia, Koku Roland Agbeko
Publisher: name: University of Iowa
Year: 2026

description: « De la violence à la révolte féministe : l’image de la femme vues par les auteurs masculins de la littérature noire africaine d’expression française des décennies pré et post indépendances » considers the representation of women in Sub-Saharan African novels in French from the 1950s to 1960s in order to demonstrate the existence of a feminist revolt avant la lettre in the works of authors such as Ferdinand Oyono, Seydou Badian, Sembène Ousmane, Guy Menga, Guillaume Ôyônô Mbia and Ahmadou Kourouma.
description: Scholarship on these novels has often focused on the colonial issues presented in these texts, which frequently denounce both colonialism and the new ruling classes that emerged following independence. Due to the focus on these colonial matters, readers have often overlooked the representation of women and gender issues, including the refusal of many rebellious characters to resign themselves to their condition and place in society, and a desire for self-liberation.
description: Without directly declaring themselves feminists, these male writers among others carried in their literary works the premonitory seeds of African feminism, dawning a new perspective for black African women’s emancipation. By doing so, these texts present a critique of the place of woman in traditional African society and represent her as being assigned a subaltern social position. She is often considered to owe the male full respect, total submission, and the ideal woman is the one who does not question her husband and other men in any way.
description: These works also satirize the way in which women are denied educational opportunities. Some of the characters believe that girls’ schooling is not important because she is destined to run her home; they believe that she does not need to read the colonizer’s language to fulfill her vii duties as a mother and maintain family unity. The character of the young girl educated in Western school who revolts against phallocracy also explains both the fear of losing his authority over her if she becomes literate and the desire of male figures to keep her in a place of obscurantism in order to better dominate her. These novels also did not fail to explore the problem of polygamy, which although somewhat accepted is often portrayed by the authors as a forced marriage and sign of the woman’s objectification.
The graphical presentation of a measure of an employee’s competence for a job position
Creators: name: BIEŃKOWSKA, Agnieszka
name: BROL, Marian
Publisher: name: Wrocław University of Technology, Wrocław University of Economics, Polish Operational and Systems Research Society
Year: 2013
Subjects: competency-based management, competence profile, measure of an employee’s competence

description: OPERATIONS RESEARCH AND DECISIONS; ISSN 2081-8858
Besonderheiten des Lernens und Lehrens auf der Bildungsstufe der 4- bis 8-Jährigen - ein Diskussionsbeitrag
Creators: name: Streit, Christine
name: Künzli, Christine
name: Hildebrandt, Elke
Publisher: name: Klinkhardt
Year: 2014
Subjects: subject: 370 - Erziehung, Schul- und Bildungswesen

description: Die Herausforderung der bildungspolitisch gewollten Annäherung des Kindergartens und der Primarunterstufe besteht darin, sich der differenten institutionellen Kulturen, aber auch der bereits bestehenden Gemeinsamkeiten bewusst zu werden und gemeinsame didaktische Vorstellungen zu entwickeln. Im Beitrag wird ein Modell zur Diskussion gestellt, welches Spezifika des Unterrichts auf dieser Bildungsstufe der sog. Eingangsstufe beschreibt und zugleich Lehrpersonen einen Orientierungsrahmen für das eigene Handeln liefern kann. Anhand eines Beispiels aus der Praxis werden das Modell sowie dessen Potential konkretisiert.
What Hindu Sati Can Teach Us about the Sociocultural and Social Psychological Dynamics of Suicide
Creators: name: Abrutyn, Seth
Publisher: name: The University of British Columbia
Year: 2018

description: By leveraging the case of Hindu sati, this paper elucidates the ways in which structure and culture condition suicidal behavior by way of social psychological and emotional dynamics. Conventionally, sati falls under Durkheim’s discussion of altruistic suicides, or the self-sacrifice of underindividuated or excessively integrated peoples like widows in traditional societies. In light of the fact that Durkheim’s interpretation was based on uneven data, nineteenth century Eurocentric beliefs, and a theoretical framework that can no longer resist modification and elaboration, by reconsidering sati it is possible to sketch a new model that strengthens Durkheim’s theory by making it more robust and generalizable. The following model is built on five principles. First, integration and regulation are not distinct causal forces, but overlapping contextual conditions. Second, to better explain the variation in suicidality across time and space, we must also pay attention to culture as it provides the underlying meanings of suicide that can increase the odds a person or class of persons become suicidal or are protected against suicidality. Third, structure still matters, but in many cases, the role power and power-differentials play must be considered. Fourth, understanding why and how people choose suicide depends on incorporating identity and status processes. Fifth, because the expression of social emotions like shame are patterned by structural and cultural conditions, to understand how suicidality is socioculturally patterned we must further explore the link between identity/status, social emotions, and structure and culture.
Journal of Applied Hermeneutics, 2014
Creators: name: Journal Of Applied Hermeneutics
Publisher: name: Journal of Applied Hermeneutics
Year: 2014

description: Guest Editorial: Old Dog. Same Trick
Conducting Hermeneutic Research: The Address of the Topic
Twins Philosophically Separated at Birth? A Review of Groundless Ground: A Study of Wittgenstein and Heidegger
Guest Editorial: This is Why We Read. This is Why We Write
My Treasured Relation
Some Introductory Words For Two Little Earth Cousins
Stories from Cancer Camp: Tales of Glitter and Gratitude
Practicing Palimpsest: Layering Stories and Disrupting Dominant Western Narratives in Early Childhood Education
The Case of the Disappearing/Appearing Slow Learner: An Interpretive Mystery
Werkstatt erarbeiten - Welt erspielen
Creators: name: Hildebrandt, Elke
name: Weisshaupt, Mark
Publisher: name: Forum Neue Medien in der Lehre Austria
Year: 2012
Subjects: subject: Unterrichtsentwicklung in der Vorschul- und Primarstufe
subject: 370 - Erziehung, Schul- und Bildungswesen

description: Der Beitrag behandelt die wenig erkannte Verbindung von Lernwerkstattarbeit und spielerischem Lernen. Diese Verbindung wird als eine Möglichkeit herausgearbeitet, um eine neue selbstgesteuerte Lernkultur in Hochschulen zu etablieren. Hierbei wird die Bedeutung des Spiels und der Spiel-Dinge für die Konstruktion der Welt bei Lernprozessen beleuchtet. Anhand der Seminarpraxis der «Lernwerkstatt SPIEL» werden pädagogische und verallgemeinerungsfähige Bedingungen der Etablierung einer spielerischen Forschungskultur diskutiert.
Regulation of aortic carboxypeptidase-like protein (ACLP) during 3T3-L1 adipogenesis.
Creators: name: Abaiian, Kayvan Jasper.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Biology, Cell.

description: The 175 kD aortic carboxypeptidase-like protein (ACLP), suggested to be involved in smooth vascular muscle cell differentiation, has been shown to be expressed in 3T3-L1 preadipocytes. In this study we demonstrate that ACLP protein expression is transiently but significantly down-regulated by day 2 of an 8-day 3T3-L1 differentiation. ACLP protein down-regulation correlates with increases in cell number, suggesting a potential link between ACLP and clonal expansion. The transient modulation of ACLP is shown to be partly due to transcriptional regulation. Analysis of the individual components of differentiation cocktail indicate that all components are necessary to induce maximal ACLP downregulation and, as such, this event is differentiation-dependent. Although ACLP overexpression had no apparent effect on adipogenesis, its pattern of expression, unique to post-mitotic proliferation, indicates a potential role for ACLP in adipose tissue development and warrants further investigation to elucidate its function during preadipocyte differentiation.
Spatiotemporal microbial community composition in the subsurface sediments of tropical peat-draining rivers in Sarawak, Malaysia
Creators: name: Denis, Nastassia
Publisher: name: Swinburne
Year: 2024

description: Growing anthropogenic disturbance in and along tropical peat-draining rivers raises concerns regarding the consequences for the global climate. The findings from this study provide vital insights into the microbial community in tropical peat-draining rivers and the impact of anthropogenic activities on these microorganisms. The drastic decrease in microbial diversity at the anthropogenically-influenced site as compared to the reference site in this study shows that anthropogenic activities have a negative effect on microbial communities.
Les concepts de Dieu dans Process and reality de Alfred North Whitehead.
Creators: name: Hurtubise, Denis.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Philosophy.

description: Jusqu'a recemment, il y avait unanimite chez les interpretes de Whitehead au sujet du concept metaphysique de Dieu elabore par celui-ci. Tous, en effet, consideraient qu'un seul concept de Dieu avait ete tenu par Whitehead au cours de sa periode metaphysique, soit de 1925 a 1941. Depuis la fin des annees 1970, mais surtout depuis 1984, annee de la parution de l'important ouvrage intitule The Emergence of Whitehead's Metaphysics (1925-1929), cette perception de la pensee de Whitehead est mise en cause par le professeur Lewis S. Ford, de Norfolk (Virginie). Il soutient qu'au contraire, le systeme metaphysique de Whitehead a evolue de maniere significative non seulement au fil des ouvrages publies par celui-ci, mais aussi, chose surprenante, au cours du processus de composition de Process and Reality (paru en 1929), son magnum opus. Ford distingue treize moments compositionnels, donc autant de couches redactionnelles dans cet ouvrage. Et, ce qui est particulierement interessant pour notre propos, il fait allusion a une historicite du concept de Dieu dans le cadre de la composition de Process and Reality. Prenant le relais des recherches de Ford, notre these se veut une demonstration de ce qu'avant d'en venir a proposer son concept final de Dieu dans Process and Reality, Whitehead fut tenant, dans les premieres etapes de la composition de cet ouvrage, d'un concept initial de Dieu nettement distinct du concept final. De la sorte, l'essentiel de notre these est consacre a l'etude de tous les textes ou, dans Process and Reality, mention est faite du mot "Dieu" de meme qu'a la reconstruction des concepts de Dieu qui sont exprimes dans les textes en question. (Abstract shortened by UMI.)
Cappelle et al - Bulletin of the WHO 2020 - Supplementary Material.pdf
Creators: name: Cappelle, Julien
Publisher: name: figshare
Year: 2020
Subjects: subject: 111706 Epidemiology
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110309 Infectious Diseases
subject: Ecology
subject: FOS: Biological sciences
subject: Anthropology
subject: FOS: Sociology

description: Supplementary Material (including supplementary Fig. 1 and dsupplementary Fig.2) for Cappelle et al., Bulletin of the WHO 2020.
Chronic pain and opioid misuse: a review of reviews
Creators: name: Voon, Pauline
name: Karamouzian, Mohammad
name: Kerr, Thomas
Publisher: name: BioMed Central
Year: 2017

description: Objective: The crisis of prescription opioid (PO) related harms has focused attention toward identifying and treating high-risk populations. This review aims to synthesize systematic reviews on the epidemiology and clinical management of comorbid chronic pain and PO or other substance misuse. Methods: A systematic database search was conducted to identify systematic reviews published between 2000 and 2016. Eligible studies were systematic reviews related to chronic non-cancer pain and PO or other substance misuse. Evidence from the included reviews was synthesized according to epidemiology and clinical management themes. Results: Of 1908 identified articles, 18 systematic reviews were eligible for final inclusion. Two meta-analyses estimated the prevalence of chronic non-cancer pain in individuals using POs non-medically to be approximately 48% to 60%, which is substantially higher than the prevalence of chronic non-cancer pain in general population samples (11% to 19%). Five systematic reviews estimated the rates of PO or other opioid use in chronic pain populations with substantial variation in results (0.05% to 81%), likely due to widely varying definitions of dependence, substance use disorder, misuse, addiction, and abuse. Several clinical assessment and treatment approaches were identified, including: standardized assessment instruments; urine drug testing; medication counts; prescription drug monitoring programs; blood level monitoring; treatment agreements; opioid selection; dosing and dispensing strategies; and opioid agonist treatment. However, the reviews commonly noted serious limitations, inconsistencies, and imprecision of studies, and a lack of evidence on effectiveness or clinical utility for the majority of these strategies. Conclusion: Overall, current systematic reviews have found a lack of high-quality evidence or consistent findings on the prevalence, risk factors, and optimal clinical assessment and treatment approaches related to concurrent chronic pain and substance misuse. Given the role of systematic reviews in guiding evidence-based medicine and health policy, there is an urgent need for high-quality primary research to guide future systematic reviews to address the escalating epidemic of harms related to chronic pain and substance misuse.
La dualité idéologique de trois sous-groupes de l'intelligentsia ouzbèke en U.R.S.S. (1964-1982)
Creators: name: Daviau, Jocelyne C.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1989
Subjects: subject: Sociology, Ethnic and Racial Studies.

description: Le sens que l'on donne aujourd'hui a l'internationalisme, ou a la "theorie" d'une pretendue "nation sovietique" (ou d'un seul "peuple sovietique"--peu importe le terme), n'est pas celui d'un Commonwealth, mais d'une unification arbitraire, qui prouve a elle seule, au moins "theoriquement", le vaste processus de russification (Dziouba, 1980: 64) Le terme de "russification" est tres impopulaire de nos jours; c'est un mot que les autorites n'aiment pas et qu'elles evitent d'employer en public car elles le considerent trop dissonant (Dziouba, 1980: 174) Pourquoi maintenir des groupes nationaux et des cultures nationales? Le probleme est pose. Pourquoi ne pas tendre vers une culture, une langue, une tradition historique universelles? Ce sont la des questions doctrinaires pour qui le nationalisme n'est qu'un obstacle a la realisation d'une societe universelle et qui ne vient en lui qu'une des pires formes du chauvinisme bourgeois. (H. Selsam cite dans Dziouba, 1980: 30) Le moindre particularisme national est considere une "survivance desuete" (a eliminer), une "barriere entre les nations" (a rompre), un "point de vue unilateral" (a vaincre), et ainsi de suite. (Dziouba, 1980: 64) L'edification du communisme implique que soit realisee l'unite complete entre les nations. Naturellement, il y en aura toujours qui pleureront la disparition des distinctions nationales. Nous leur repondrons que les communistes ne sont pas donne pour but de preserver les differences entre les nations ni de les favoriser (Krouchtchev, cite dans Dziouba, 1980: 237)
Developing mobile distributed intelligent network services using RM-ODP.
Creators: name: Rampal, Gaurav S.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1998
Subjects: subject: Artificial Intelligence.

description: The Intelligent Network (IN) is a conceptual model for a service development technology to create telecommunication services. In its current form, IN is limited to service creation in isolated networks and cannot support co-operative service development between two or more networks. Rapid development in networking paradigms and standards has led to an urgent need of finding solutions to the problem of interworking heterogeneous networks. Differing abstraction levels make meaningful exchange of information difficult, and IN has not been able to meet this requirement. The Reference Model for Open Distributed Processing (RM-ODP) is a distributed object based architecture which provides a high level framework for distributed systems. The emphasis is to develop a set of re-usable functional abstractions that can be recombined in various configurations to develop required applications. This work uses RM-ODP framework to supplement deficiencies evident in IN. Two specific aspects are examined and developed. The first is service portability through service profile modeling. A model for service development in a mobile environment, and related concepts of service profile modeling and transfer are developed. The second, IN domain interworking in the ODP framework. A ODP framework for the modeling of this service profile and its migration as the user moves to different domains is proposed. Our approach allows dynamically configured interworking of domains.
Nintendian Jazz: Centering Jazz in Nintendo’s Approach to Ludic Scoring Practices
Creators: name: Heazlewood-Dale, James C.
Publisher: name: Brandeis University
Year: 2024
Subjects: Film Scoring
Jazz Studies
Ludomusicology
Nintendo
Super Mario
Popular Music

description: In 1917, the Original Dixieland Jazz Band recorded and released "Livery Stable Blues," the first commercially accessible jazz recording. Since the ensemble's hit recording, "jazz"—the sounds we associate with it, the people who make it, the audiences that listen to it, the places musicians perform it, and the modes of mediating it —has changed innumerably. In 2017, a century later, the Japanese video game company Nintendo released a new title for their cornerstone series featuring a short (but dynamic), mustached Italian plumber: Super Mario Odyssey. Along with conferring several new ludic powers to Mario, Nintendo positioned jazz at the center of the game's soundscape. This historical coincidence of these two examples being one hundred years apart speaks to the ongoing significance and influence of jazz in twenty-first century culture. It also perfectly encapsulates the crux of this thesis's discussion: What is the relationship between jazz and video game music? This dissertation explores the intersection of jazz and video game music, focusing on the significant role jazz plays in a Nintendian approach to ludic scoring practices and highlights the multifaceted nature of jazz, advocating for a pluralistic understanding of the idiom. Within the field of ludomusicology, the influences and functions of jazz in video games have been largely overlooked. This large-scale study addresses this gap by examining how Nintendo integrates jazz into its scoring for various game titles, including Super Mario Odyssey, Super Mario Bros., Super Mario Bros. 2, Super Mario Bros. 3, and Super Mario World. Furthermore, this work investigates the influence of Nintendo's jazz scoring on contemporary jazz performance practices. I discuss the growing number of contemporary musicians whose output comprises jazz-informed renditions of video game music and situate these musicians' artistic production within broader historical practices in jazz where musicians draw from popular media for performance repertoires. Finally, this study emphasizes the pedagogical potential of analyzing jazz solos within Nintendo games to develop jazz improvisation skills. Within Nintendo's scores, jazz participates in a musical conversation involving many idioms. This, perhaps more than anything else, speaks to the eclectic approach to game design that Nintendo has developed and embraced, creating a thread between the soundscapes of their many games. Jazz is central to the hybridized sonic tapestry that contributes to Nintendo's acclaimed conception of sound, music, and play.
ГЕСТАЦИОННЫЙ САХАРНЫЙ ДИАБЕТ И НЕБЛАГОПРИЯТНЫЕ МАТЕРИНСКИЕ И ПЕРИНАТАЛЬНЫЕ ИСХОДЫ ПРИ ДВОЙНЕ И ОДНОПЛОДНОЙ БЕРЕМЕННОСТИ: СИСТЕМАТИЧЕСКИЙ ОБЗОР И МЕТА-АНАЛИЗ.
Creators: name: Умарова, Наргиза
name: Абидова, Н.Б.
Publisher: name: Zenodo
Year: 2024

description: Исследование предполагает, что гестационный сахарный диабет (ГСД) следует разделить на два подтипа в зависимости от повышенного уровня глюкозы в крови натощак. Подтип PGDM-HR имеет худшие материнские и неонатальные исходы по сравнению с подтипом гестационного сахарного диабета-LR- -LR. У женщин с повышенным уровнем глюкозы в крови натощак чаще наблюдается стабильная дисфункция β-клеток, хроническое снижение массы β-клеток, снижение чувствительности печени к инсулину и предрасположенность к сахарному диабету 2 типа.
Financing medtech innovation in Melbourne: a case study in economic and phenomenological sociology
Creators: name: Hawa, Joelle
Publisher: name: Swinburne
Year: 2024

description: The thesis examines how Australian medtech entrepreneurs, venture capitalists and government officials make sense of their environment and engage in the development of the medtech financing space and the medtech innovation system of Melbourne. The findings from this qualitative study suggests that the multiple meanings emergent from the three sets of actors create a cycle of disconnect, leading to struggles and incremental development of the medtech innovation financing field and the medtech innovation system of Melbourne. This study highlights the tensions existent in the medtech innovation field providing evidence based implications for policymakers working in the medtech innovation field.
Intervention Engagement Moderates the Dose–Response Relationships in a Dietary Intervention
Creators: name: Lippke, Sonia
name: Corbet, Jana M.
name: Lange, Daniela
name: Parschau, Linda
name: Schwarzer, Ralf
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: moderated mediation
subject: randomized controlled trial intentions
subject: planning
subject: nutrition
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Behavioral interventions could lead to changes in behavior through changes in a mediator. This dose–response relationship might only hold true for those participants who are actively engaged in interventions. This Internet study investigated the role of engagement in a planning intervention to promote fruit and vegetable consumption in addition to testing the intervention effect on planning and behavior. A sample of 701 adults (mean = 38.71 years, 81% women) were randomly assigned either to a planning intervention (experimental group) or to one of 2 control conditions (untreated waiting list control group or placebo active control group). Moderated mediation analyses were carried out. Significant changes over time and time × group effects revealed the effectiveness of the intervention. The effect of the intervention (time 1) on changes in behavior (time 3; 1 month after the personal deadline study participants set for themselves to start implementing their plans) was mediated by changes in planning (time 2; 1 week the personal deadline). Effects of planning on behavior were documented only at a moderate level of intervention engagement. This indicates an inverse U-shaped dose–response effect. Thus, examining participants’ intervention engagement allows for a more careful evaluation of why some interventions work and others do not.
Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients
Creators: name: Russell, James A
name: Vincent, Jean-Louis
name: Kjølbye, Anne L
name: Olsson, Håkan
name: Blemings, Allan
name: Spapen, Herbert
name: Carl, Peder
name: Laterre, Pierre-Francois
name: Grundemar, Lars
Publisher: name: BioMed Central
Year: 2017

description: Background: Vasopressin is widely used for vasopressor support in septic shock patients, but experimental evidence suggests that selective V1A agonists are superior. The initial pharmacodynamic effects, pharmacokinetics, and safety of selepressin, a novel V1A-selective vasopressin analogue, was examined in a phase IIa trial in septic shock patients. Methods: This was a randomized, double-blind, placebo-controlled multicenter trial in 53 patients in early septic shock (aged ≥18 years, fluid resuscitation, requiring vasopressor support) who received selepressin 1.25 ng/kg/minute (n = 10), 2.5 ng/kg/minute (n = 19), 3.75 ng/kg/minute (n = 2), or placebo (n = 21) until shock resolution or a maximum of 7 days. If mean arterial pressure (MAP) ≥65 mmHg was not maintained, open-label norepinephrine was added. Co-primary endpoints were maintenance of MAP >60 mmHg without norepinephrine, norepinephrine dose, and proportion of patients maintaining MAP >60 mmHg with or without norepinephrine over 7 days. Secondary endpoints included cumulative fluid balance, organ dysfunction, pharmacokinetics, and safety. Results: A higher proportion of the patients receiving 2.5 ng/kg/minute selepressin maintained MAP >60 mmHg without norepinephrine (about 50% and 70% at 12 and 24 h, respectively) vs. 1.25 ng/kg/minute selepressin and placebo (p < 0.01). The 7-day cumulative doses of norepinephrine were 761, 659, and 249 μg/kg (placebo 1.25 ng/kg/minute and 2.5 ng/kg/minute, respectively; 2.5 ng/kg/minute vs. placebo; p < 0.01). Norepinephrine infusion was weaned more rapidly in selepressin 2.5 ng/kg/minute vs. placebo (0.04 vs. 0.18 μg/kg/minute at 24 h, p < 0.001), successfully maintaining target MAP and reducing norepinephrine dose vs. placebo (first 24 h, p < 0.001). Cumulative net fluid balance was lower from day 5 onward in the selepressin 2.5 ng/kg/minute group vs. placebo (p < 0.05). The selepressin 2.5 ng/kg/minute group had a greater proportion of days alive and free of ventilation vs. placebo (p < 0.02). Selepressin (2.5 ng/kg/minute) was well tolerated, with a similar frequency of treatment-emergent adverse events for selepressin 2.5 ng/kg/minute and placebo. Two patients were infused at 3.75 ng/kg/minute, one of whom had the study drug infusion discontinued for possible safety reasons, with subsequent discontinuation of this dose group. Conclusions: In septic shock patients, selepressin 2.5 ng/kg/minute was able to rapidly replace norepinephrine while maintaining adequate MAP, and it may improve fluid balance and shorten the time of mechanical ventilation. Trial registration ClinicalTrials.gov, NCT01000649 . Registered on September 30, 2009.
Studies on rabies virus polymorphism.
Creators: name: Ogbebor, Omokhaye P.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2002
Subjects: subject: Biology, Microbiology.

description: Rabies viruses have very simple genomes made up of single-stranded, negative sense, non-segmented ribonucleic acid (RNA). Most, if not all RNA virus populations may exist as complex mixtures of genetic and phenotypic variants often referred to as quasispecies populations. A quantitative relative fitness assay has previously been used to demonstrate loss of fitness in RNA virus populations due to Muller's Ratchet and to show gains of fitness by natural selection during virus passages. Due to their mutation rates, rapid replication, large population sizes and controlled (variable or constant) host cells, RNA viruses are useful for examining evolutionary processes. This study uses rabies virus as a model to examine virus evolution and virus population biology. The fate of two closely related rabies virus variants (the Western Skunk and Eastern Artic Fox viruses), cloned using end-point dilution techniques, passaged by themselves and in competition to each other in mouse neuroblastoma (MNA) cells was investigated. (Abstract shortened by UMI.)
GI Elections with POLYAS: a Road to End-to-End Verifiable Elections
Creators: name: Beckert, Bernhard
name: Brelle, Achim
name: Grimm, Rüdiger
name: Huber, Nicolas
name: Kirsten, Michael
name: Küsters, Ralf
name: Müller-Quade, Jörn
name: Noppel, Maximilian
name: Reinhard, Kai
name: Schwab, Jonas
name: Schwerdt, Rebecca
name: Truderung, Tomasz
name: Volkamer, Melanie
name: Winter, Cornelia
Publisher: name: Karlsruhe
Year: 2019

description: Starting from 2019, the annual elections of the GI (German Society for Computer Scientists) will be carried out using a new online voting system developed by POLYAS, aiming at providing high, state-of-the-art security guarantees. We describe the steps that POLYAS plans to take together with the GI and academic partners in order to achieve the level of transparency and trust that is expected from modern online voting. The participation of the academic partners is the key factor to make the verification process both practical and meaningful.
Beyond her arrival
Creators: name: Kelly, Katrice
Publisher: name: University of Iowa
Year: 2024

description: My interest in art began with finding a source to relieve my anger. Being one of the youngest of nine siblings, I often faced difficulty during my upbringing, which led to frustration and the feeling of being misunderstood. Finding my identity was hard because everything I wore, learned, read, or owned was handed down. While most of my siblings were pursuing an interest in sports, pageants, and other school activities, I was left with little to choose from. However, art was accessible and had no additional burden on my family. The first art piece I created came about because my older brothers had broken a toy, one of those moving screen toys that play music simultaneously like a TV I could finally call my own. I fixed the toy by recreating the whole toy using a cereal box, a plastic bag, paper towel rolls, crayon tape, and some glue. This little spark of genius not only simmered the frustration I felt toward my brother but also brought an opening to my natural talent. Most of my professional art experiences involved children or working with other pursuing artists. Beyond using a brush and paint, I explored more possibilities to bring an idea to life. I have used human and synthetic hair, beading, jewelry, false flowers, printmaking, printed paper, and many forms of ephemera.
title: Advancing social insights through NLP
title: social media reactions, mental health and beyond
titleType: Subtitle
Creators: name: Huang, Chengyue
Publisher: name: University of Iowa
Year: 2024
Subjects: Artificial Intelligence
Natural Language Processing
Social Media Analytics
Machine Learning
Mental Health

description: This thesis presents a comprehensive exploration into the digital landscape’s influence on public policy and mental health through the lens of social media analysis and natural language processing. It comprises three interconnected studies that collectively aim to understand and address challenges in policy-making, mental health, and social dynamics in the context of major societal events such as the COVID-19 pandemic.
description: The first segment of the thesis examines the politicization of policy responses in public and business domains. Utilizing 2.6 million tweets and employing BERT and zero-shot learning, we identify how politicization affects public opinion and policy efficacy. This analysis reveals that politicized anti-policy tweets gain more propagation, emphasizing peripheral route of persuasion rather than central route, whereas pro-policy tweets garner less attention. The study concludes with recommendations for de-politicization strategies to enhance policy effectiveness.
description: In the second study, the focus shifts to the mental health impact of the COVID19 pandemic, specifically on the well-being of different demographic groups. By analyzing Reddit data with a multivariate approach, the study quantifies changes in sentiment, stress, and loneliness, highlighting the disproportionate impact on younger women. The results underscore the need for policy reforms to support women’s dual roles during crises like the pandemic.
description: Building upon the insights gained in the second study, the third part addresses the rising issue of loneliness, intensified by the pandemic. We investigate an automated approach for identifying loneliness on social media which employs a topicaware lexicon to refine machine learning models.
description: Together, these studies provide valuable insights into how digital communication and social media platforms intersect with public policy, mental health, and societal iii well-being. The thesis underscores the importance of nuanced understanding and informed intervention in these domains, leveraging the power of natural language processing and social media analytics.
Transcription factors providing myogenic identity to adult muscle satellite cells
Creators: name: Ishibashi, Jeff
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2007
Subjects: subject: Biology, Molecular.

description: Satellite cells are an adult stem cell population that provide for the regeneration of skeletal muscle. Two major families of transcription factors, the paired-box (Pax) factors and the myogenic regulatory factors (MRFs), have essential roles in specifying that satellite cells become skeletal muscle. It was hypothesized that three of these proteins (Pax7, Myf5, MyoD) have particularly important roles in providing this identity, due to their unique roles in activating the skeletal muscle program. Each was studied using a combination of molecular techniques, including genome-wide microarrays, PCR-based systems, protein assays, and immunostaining, to assess their effects on myoblast gene expression and function. In the absence of Pax7, adult myoblasts are lost through a p53-dependent pathway. Pax7 also regulates the expression of numerous genes in myoblasts, including Myf5. Alternative splicing within the Pax7 paired domain alters its ability to activate expression of target genes, including Myf5. Although Myf5 and MyoD are both expressed in growing myoblasts and are grossly redundant, MyoD uniquely primes myoblasts for differentiation through its divergent NH2- and COOH-terminal regions that flank the conserved bHLH domain. Therefore, Pax7, Myf5, and MyoD supply specific myogenic functions in satellite cells that provide for robust repair of injury to skeletal muscle tissue.
title: Inhibitory control, impulsivity, and recreational substance use
Creators: name: Ward, Elizabeth Rebecca
Publisher: name: Goldsmiths, University of London
Year: 2010

description: This thesis explores the involvement of self-control and inhibitory control mechanisms in the early stages of drug use and addiction, and investigates specific psychological processes that are thought to be risk factors for substance use and abuse. An "Intention, Impulse and Control (lIC) framework" is developed, uniting principles drawn from a variety of contemporary perspectives in identifying factors likely to influence whether an individual encounters and engages in substance use. Interrelationships between different self-report and laboratory-based behavioural measures of the psychological constructs implicated by this framework are examined via a cross-sectional study of 497 undergraduate students. Reflecting other findings in the literature, associations between self-report and behavioural measures are found to be weak or non-existent. Factor analysis of the self-report measures yields indices of three key trait constructs: approach tendencies, avoidance tendencies, and cognitive control. The ensuing research programme tests some predictions of the lIC framework, assessing cross-sectional and longitudinal relationships in a large sample of students who use alcohol and other substances recreationally. Cross-sectional analyses probe the differential involvement of various factors including attitudes, recent stress, approach tendencies, avoidance tendencies, and cognitive control. Substance use is found to be strongly associated with attitudes, life stress, and cognitive control, but not with approach or avoidance tendencies. For a subset of 88 participants who were reassessed between one and two years after baseline testing, longitudinal analyses address whether (a) pre-existing impairments of self-control processes predispose some individuals towards substance abuse, and (b) substance use itself leads to diminished self-control. Although methodological limitations mean that caution is needed when interpreting these data, the analyses indicate no causal connections between cognitive control, either at baseline or in terms of change over time, and changes in substance use. The implications of the findings for current theories of addiction, and for future research, are considered.
The Intricate Relationship between Psychotic-Like Experiences and Associated Subclinical Symptoms in Healthy Individuals
Creators: name: Unterrassner, Lui
name: Wyss, Thomas A.
name: Wotruba, Diana
name: Haker, Helene
name: Roessler, Wulf
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The interplay between subclinical psychotic, negative, and affective symptoms has gained increased attention regarding the etiology of psychosis spectrum and other mental disorders. Importantly, research has tended to not differentiate between different subtypes of psychotic-like experiences (PLE) although they may not have the same significance for mental health. In order to gain information on the subclinical interplay between specific PLE and other symptoms as well as the significance of PLE for mental health, we investigated their specific associations in 206 healthy individuals (20–60 years, 73 females) using correlational and linear regression analyses. PLE were assessed with the Magical Ideation Questionnaire, the revised Exceptional Experiences Questionnaire, and subscales of the Schizotypal Personality Questionnaire (SPQ). The revised Symptom Checklist 90, the SPQ, and the Physical Anhedonia Scale were used to measure subclinical negative symptoms, affective symptoms, and other symptoms such as, emotional instability. As hypothesized, we found that (1) most affective symptoms and all other subclinical symptoms correlated positively with all PLE, whereas we found only partial associations between negative symptoms and PLE. Notably, (2) magical ideation and paranormal beliefs correlated negatively with physical anhedonia. In the regression analyses we found (3) similar patterns of specific positive associations between PLE and other subclinical symptoms: Suspiciousness was a specific predictor of negative-like symptoms, whereas ideas of reference, unusual perceptual experiences, and dissociative anomalous perceptions specifically predicted anxiety symptoms. Interestingly, (4) ideas of reference negatively predicted physical anhedonia. Similarly, paranormal beliefs were negatively associated with constricted affect. Moreover, odd beliefs were a negative predictor of depression, emotional instability, and unspecific symptoms. Our findings indicated that subtypes of PLE are differentially implicated in psychological functioning and should therefore not be categorized homogeneously. Moreover, paranormal beliefs, odd beliefs, and partly ideas of reference might also contribute to subjective well being in healthy individuals. Our results might serve as a starting point for longitudinal studies investigating the interplay of subtypes of subclinical symptoms along a psychopathological trajectory leading to mental disorders. Importantly, this research might help to improve therapeutic strategies for psychosis prevention.