cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Performing biography: creating, embodying and shifting history [2 parts]
Creators: name: Meenach, Bernadette Anne
Publisher: name: University of Southern Queensland
Year: 2018
Subjects: subject: 190404 Drama, Theatre and Performance Studies
subject: 210304 Biography

description: Performing Biography: creating, embodying and shifting history is a practice-led research project that builds upon and challenges Canton’s (2011) research into biographical theatre. Canton suggests that biographical theatre cannot shift audience perception of an historical figure if it counters their previous 'life world knowledge', regardless of the modernist or postmodernist theatrical devices employed. Through three cycles of observation, reflection, planning and, action two original biographical theatre works are created, embodied and performed. They are designed to test whether biographical theatre can shift audience perception of an historical figure if three emergent biographical theatre-making principles are considered. The modernist Ms. Garland at Twilight and the postmodernist Judy Strikes Back prove that biographical theatre could shift audience perception. In extant biographical theatre works featuring the actress Judy Garland, her life is constructed through the tragedy plotting pattern. According to White (1978), Davis (1992), Heddon (2008) and Dortins (2009) such a pattern, or dominant narrative, has the power to limit, distort or police control over the life story of an historical figure. By successfully disrupting the tragedy narrative associated with Garland, this study proposes that ‘khorobiognosis’ can occur. That is, audience perception can be shifted if the biographer and biographical performers commit to their super-objective, include other people’s thinking, and embrace liveness. This study provides a narrative of my biographical theatre-making practice to ensure that new narratives of historical figures can be revealed and forgotten narratives can be uncovered.
Challenges of Homogeneous Electrocatalysts for Hydrogen Evolution - Evaluation and Application for Use in Earth-Abundant Transition-Metal Systems
Creators: name: Martin, Daniel James
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The pursuit of sunlight-to-fuels technology has motivated researchers to explore electrocatalysts for the production of chemical fuels like hydrogen. These efforts have spanned both homogeneous and heterogeneous systems. Molecular electrocatalysts are particularly attractive targets of study because their electronic structure can be readily tuned through ligand modification, their secondary coordination sphere can be modified to promotes substrate stabilization or provide a substrate relay, and mechanistic and kinetic information can be gleaned through electrochemical or spectroscopic methods. Although such molecular species and forms of analysis may seem favorable, they are often prone to inherent challenges of electrocatalytic systems. One form of error is introduced when a proton source is supplied to the system. Protons are required for the electrocatalytic production of hydrogen; however, an alternative pathway, direct acid reduction at the electrode surface, may obscure the catalytic data of interest. The decomposition of molecular catalysts under electrocatalytic conditions is another concern. Catalysts that undergo degradation may devolve into alternative active species. Understanding and evaluating the mechanism by which these molecular species decompose is crucial for designing future electrocatalysts. Assembling a toolbox for handling these challenges enables the application of established work for the development and assessment of additional molecular catalysts for hydrogen evolution.
Numerical Simulations of Turbulent Molecular Clouds Regulated by Reprocessed Radiation Feedback from Nascent Super Star Clusters
Creators: name: Skinner, M. Aaron
name: Ostriker, Eve C.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Radiation feedback from young star clusters embedded in giant molecular clouds (GMCs) is believed to be important to the control of star formation. For the most massive and dense clouds, including those in which super star clusters (SSCs) are born, pressure from reprocessed radiation exerted on dust grains may disperse a significant portion of the cloud mass back into the interstellar medium (ISM). Using our radiaton hydrodynamics (RHD) code, Hyperion, we conduct a series of numerical simulations to test this idea. Our models follow the evolution of self-gravitating, strongly turbulent clouds in which collapsing regions are replaced by radiating sink particles representing stellar clusters. We evaluate the dependence of the star formation efficiency (SFE) on the size and mass of the cloud and $κ$, the opacity of the gas to infrared (IR) radiation. We find that the single most important parameter determining the evolutionary outcome is $κ$, with $κ\gtrsim 15 \text{ cm}^2 \text{ g}^{-1}$ needed to disrupt clouds. For $κ= 20-40 \text{ cm}^2 \text{ g}^{-1}$, the resulting SFE=50-70% is similar to empirical estimates for some SSC-forming clouds. The opacities required for GMC disruption likely apply only in dust-enriched environments. We find that the subgrid model approach of boosting the direct radiation force $L/c$ by a "trapping factor" equal to a cloud's mean IR optical depth can overestimate the true radiation force by factors of $\sim 4-5$. We conclude that feedback from reprocessed IR radiation alone is unlikely to significantly reduce star formation within GMCs unless their dust abundances or cluster light-to-mass ratios are enhanced.
description: 19 pages, 18 figures, accepted for publication in ApJ
The Baryon Cycle at High Redshifts: Effects of Galactic Winds on Galaxy Evolution in Overdense and Average Regions
Creators: name: Sadoun, Raphael
name: Shlosman, Isaac
name: Choi, Jun-Hwan
name: Romano-Díaz, Emilio
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We employ high-resolution cosmological zoom-in simulations focusing on a high-sigma peak and an average cosmological field at $z\sim 6-12$, in order to investigate the influence of environment and baryonic feedback on galaxy evolution in the reionization epoch. Strong feedback, e.g., galactic winds, caused by elevated star formation rates (SFRs) is expected to play an important role in this evolution. We compare different outflow prescriptions: (i) constant wind velocity (CW), (ii) variable wind scaling with galaxy properties (VW), and (iii) no outflows (NW). The overdensity leads to accelerated evolution of dark matter and baryonic structures, absent in the "normal" region, and to shallow galaxy stellar mass functions at the low-mass end. Although CW shows little dependence on both environments, the more physically motivated VW model does exhibit this effect. In addition, VW can reproduce the observed specific SFR (sSFR) and the sSFR-stellar mass relation, which CW and NW fail to satisfy simultaneously. Winds also differ substantially in affecting the state of the intergalactic medium (IGM). The difference lies in volume-filling factor of hot, high-metallicity gas which is near unity for CW, while it remains confined in massive filaments for VW, and locked up in galaxies for NW. Such gas is nearly absent in the normal region. Although all wind models suffer from deficiencies, the VW model seems to be promising in correlating the outflow properties to those of host galaxies. Further constraints on the state of the IGM at high-$z$ are needed to separate different wind models.
description: 22 pages, 15 figures, accepted for publication in the Astrophysical Journal
2D CAD
Creators: name: Honeycutt, Wesley
name: Heaston, Alyse
name: Kelly, Jeff
name: Bridge, Eli
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: aeroecology
subject: astronomy
subject: biology
subject: bird
subject: bird watching
subject: ecology
subject: hardware
subject: HardwareX
subject: LunAero
subject: lunar
subject: migrant
subject: migration
subject: moon
subject: moon watching
subject: Numpy
subject: OpenCV
subject: Open Hardware
subject: ornithology
subject: Python
subject: robotics
subject: video

description: CAD files for the construction of a LunAero unit.
A one-piece 3D printed flexure translation stage for open-source microscopy
Creators: name: Sharkey, James P.
name: Foo, Darryl C. W.
name: Kabla, Alexandre
name: Baumberg, Jeremy J.
name: Bowman, Richard W.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: Open source hardware has the potential to revolutionise the way we build scientific instruments; with the advent of readily-available 3D printers, mechanical designs can now be shared, improved and replicated faster and more easily than ever before. However, printed parts are typically plastic and often perform poorly compared to traditionally machined mechanisms. We have overcome many of the limitations of 3D printed mechanisms by exploiting the compliance of the plastic to produce a monolithic 3D printed flexure translation stage, capable of sub-micron-scale motion over a range of $8\times8\times4\,$mm. This requires minimal post-print clean-up, and can be automated with readily-available stepper motors. The resulting plastic composite structure is very stiff and exhibits remarkably low drift, moving less than $20\,μ$m over the course of a week, without temperature stabilisation. This enables us to construct a miniature microscope with excellent mechanical stability, perfect for timelapse measurements in situ in an incubator or fume hood. The ease of manufacture lends itself to use in containment facilities where disposability is advantageous, and to experiments requiring many microscopes in parallel. High performance mechanisms based on printed flexures need not be limited to microscopy, and we anticipate their use in other devices both within the laboratory and beyond.
description: 7 pages, 10 figures
R Coronae Borealis Stars are Viable Factories of Pre-solar Grains
Creators: name: Karakas, Amanda I.
name: Ruiter, Ashley J.
name: Hampel, Melanie
Publisher: name: arXiv
Year: 2015
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a new theoretical estimate for the birthrate of R Coronae Borealis (RCB) stars that is in agreement with recent observational data. We find the current Galactic birthrate of RCB stars to be $\approx$ 25% of the Galactic rate of Type Ia supernovae, assuming that RCB stars are formed through the merger of carbon-oxygen and helium-rich white dwarfs. Our new RCB birthrate ($1.8 \times 10^{-3}$ yr$^{-1}$) is a factor of 10 lower than previous theoretical estimates. This results in roughly 180--540 RCB stars in the Galaxy, depending on the RCB lifetime. From the theoretical and observational estimates, we calculate the total dust production from RCB stars and compare this rate to dust production from novae and born-again asymptotic giant branch (AGB) stars. We find that the amount of dust produced by RCB stars is comparable to the amounts produced by novae or born-again post-AGB stars, indicating that these merger objects are a viable source of carbonaceous pre-solar grains in the Galaxy. There are graphite grains with carbon and oxygen isotopic ratios consistent with the observed composition of RCB stars, adding weight to the suggestion that these rare objects are a source of stardust grains.
description: Accepted for publication in The Astrophysical Journal, 7 pages
Conceptual design of elliptical cavities for intensity and position sensitive beam measurements in storage rings
Creators: name: Sanjari, M. S.
name: Chen, X.
name: Hülsmann, P.
name: Litvinov, Yu. A.
name: Nolden, F.
name: Piotrowski, J.
name: Steck, M.
name: Stöhlker, Th.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: Position sensitive beam monitors are indispensable for the beam diagnostics in storage rings. Apart from their applications in the measurements of beam parameters, they can be used in non-destructive in-ring decay studies of radioactive ion beams as well as enhancing precision in the isochronous mass measurement technique. In this work, we introduce a novel approach based on cavities with elliptical cross-section, in order to compensate for existing limitations in ion storage rings. The design is aimed primarily for future heavy ion storage rings of the FAIR project. The conceptual design is discussed together with simulation results.
description: Added definition of Uv and Pdiss in the introduction section. Added Mode numbering in table 1 and figure 1 for more clarity. Corrected one wrong figure reference. Other minor typo corrections
As You Were Mandated
Creators: name: Telling, Blayne
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Includes: The Mandates; The North‐East Quadrant; The Speech; The Blood; The Rally; The Net; The Spark; The Things They Burned; The Ashes; The Docks Girl on Dry Land; The Borderlands; The Naked Nun; The Kingpin; The Mall; The Tents; The Ruins of History; The
Tour; The Eviction
The Prym-Green Conjecture for torsion bundles of high order
Creators: name: Farkas, Gavril
name: Kemeny, Michael
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Commutative Algebra (math.AC)
subject: FOS: Mathematics

description: The Prym-Green Conjecture predicts that the resolution of a generic n-torsion paracanonical curve of every genus is natural. The conjecture has mostly been studied so far for level 2, that is, for Prym-canonical curves. Using a construction of Barth and Verra that realizes torsion bundles on sections of special K3 surfaces, we prove the Prym-Green Conjecture for curves of odd genus g and torsion bundles of sufficiently high order with respect to g. We also give partial results in even genus. In the process, we confirm the expectation of Barth and Verra concerning the number of curves in a fixed linear system on a K3 surface, having an n-torsion line bundle induced by restriction from the K3 surface.
description: 15 pages, some results strengthened. Final version, to appear in Duke Math. Journal
Identifying determinants of conformational stability in GTPases
Creators: name: Sridharan, Vishwajith
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Cellular functionalities are contingent upon the ability of proteins to maintain or transform their
shape (conformation). The molecular forces that govern protein folding have long been known1. These
include hydrophobic interactions, hydrogen bonding, and disulfide bonds. However, how proteins
maintain their conformation remains largely unanswered. In this study, twenty G proteins from
Saccharomyces cerevisiae were cloned, purified from E. coli, and tested for conformational stability. The
proteins vary in T[m] from 35 to 60°C. This is paradoxical considering their highly analogous crystal
structures and identical catalytic activity. We find that thermal stability correlates with percentage of Cys,
Met, or Pro residues in the primary sequence. We also find that the stabilities group by their respective
family members, with the following trend observed for least to most thermostable G proteins: Rho/Cdc42
< Ran < Large G-proteins < Ras < Rab < Sar/Arf. Both these results suggest that thermal stability has a
greater dependence on primary sequence than tertiary structure. Ultimately, a more detailed understanding
of protein stability can help in engineering enzymes for new molecular therapeutics.
Characteristics and Impacts of Community Aphasia Group Facilitation - A Systematic Scoping Review
Creators: name: Pettigrove, Kathryn
name: Lanyon, Lucette
name: Attard, Michelle
name: Vuong, Genevieve
name: Rose, Miranda
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Speech Pathology and Audiology
subject: Medicine and Health Sciences
subject: Communication Sciences and Disorders
subject: Rehabilitation and Therapy
subject: Mental and Social Health
subject: Community Health

description: A scoping review looking at descriptions of community aphasia groups, with a particular focus on their facilitation (who they are facilitated by, the reported characteristics of facilitation, impacts of different facilitation models and approaches)
EFL Classroom Management at the Higher Secondary Schools
Creators: name: Islam, Nazrul
Publisher: name: Zenodo
Year: 2023
Subjects: Principle, Procedure, Achievement, Classroom management, Responsibility.

description: Hi all! I completed my MA in English Language Teaching (ELT) at Jahangirnagar University, Savar, Dhaka, and this dissertation partially fulfilled my MA degree in ELT. This was my first work, and I edited some errors before publishing it online. I hope it will help a bit in researching EFL Classroom Management. If anyone gets help a bit, I will be happy and enthusiastic. Researcher
Frustrated topological symmetry breaking: geometrical frustration and anyon condensation
Creators: name: Schulz, Marc D.
name: Burnell, Fiona J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We study the phase diagram of a topological string-net type lattice model in the presence of geometrically frustrated interactions. These interactions drive several phase transitions that reduce the topological order, leading to a rich phase diagram including both Abelian ($\mathbb{Z}_2$) and non-Abelian ($\text{Ising}\times \overline{\text{Ising}}$) topologically ordered phases, as well as phases with broken translational symmetry. Interestingly, one of these phases simultaneously exhibits (Abelian) topological order and long-ranged order due to translational symmetry breaking, with non-trivial interactions between excitations in the topological order and defects in the long-ranged order. We introduce a variety of effective models, valid along certain lines in the phase diagram, which can be used to characterize both topological and symmetry-breaking order in these phases, and in many cases allow us to characterize the phase transitions that separate them. We use exact diagonalization and high-order series expansion to study areas of the phase diagram where these models break down, and to approximate the location of the phase boundaries.
description: 16+11 pages
A non-parametric k-nearest neighbour entropy estimator
Creators: name: Lombardi, Damiano
name: Pant, Sanjay
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: Numerical Analysis (math.NA)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: A non-parametric k-nearest neighbour based entropy estimator is proposed. It improves on the classical Kozachenko-Leonenko estimator by considering non-uniform probability densities in the region of k-nearest neighbours around each sample point. It aims at improving the classical estimators in three situations: first, when the dimensionality of the random variable is large; second, when near-functional relationships leading to high correlation between components of the random variable are present; and third, when the marginal variances of random variable components vary significantly with respect to each other. Heuristics on the error of the proposed and classical estimators are presented. Finally, the proposed estimator is tested for a variety of distributions in successively increasing dimensions and in the presence of a near-functional relationship. Its performance is compared with a classical estimator and shown to be a significant improvement.
The Hand that Rules the World: Gender, Parenting, and Intergenerational Political Beliefs
Creators: name: Tillett, Jillian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: This thesis explores how the presence or absence of gender role-based differences between parents shape the political leanings of their children. Studies find that the roles each parent takes on in the household may shape their own views on any number of policies (Elder & Greene 2012). In order to assess how the parental expression of gender roles and parents’ resulting political alignments impact the political leanings of their children by young adulthood, an online survey was conducted on 118 undergraduate students at the University of North Carolina at Chapel Hill. The students were asked about the political party affiliations and ideologies of themselves and their parents, and their parents’ primary roles in their families – such as caregiving and housework. The results, while not all significant, hint that the more predominant a role that mothers play in caring for children, the more likely mothers and their children will identify as Democrats and liberals, and the greater political influence they will have over offspring. Additionally, the results fit with the idea that the more both parents share in caregiving duties, the more often mothers will identify as Republicans and conservatives, and the more their children will align with the Republican Party, third parties, and ideological conservatism. These patterns in my findings are congruent with the idea that involved fathers have more political influence over their children than those who are less involved, and they tend to raise more right-leaning children overall.
Neuromodulation via ionic actuation of potassium: an in silico study
Creators: name: Verardo, Claudio
name: Mele, Leandro Julian
name: Jolivet, Renaud
name: Giugliano, Michele
name: Selmi, Luca
name: Palestri, Pierpaolo
Publisher: name: Zenodo
Year: 2022

description: Abstract: Aims. The concentration of potassium K+ in the extracellular environment is a crucial modulator of neuronal excitability. Recent advances in the technology of ionic actuators are enabling spatiotemporal resolution at the scale of neuronal cells and action potentials, thereby holding the promise of making the control of K+ concentration a viable neuromodulation modality. In this regard, in silico studies are pivotal to understand the possibilities offered by such technology. Methods. To this aim, we first introduce a theoretical framework based on the Hodgkin-Huxley formalism and bifurcation analysis. We then propose a computational approach to couple the circuit-level description of neural membranes with the finite element modeling (FEM) of ionic transport in cellular fluids and ionic actuators. As case studies, we assume cortical neurons as target cells and PEDOT:PSS-coated electrodes as iontronic transducers. Results. Bifurcation analysis suggests different K+-induced modulation of neural excitability, depending on the targeted cell. Remarkably, K+-induced tonic spiking is not for granted. Simulations enable to assess if neural activity is elicited or inhibited by the ionic actuator as a function of the extracellular geometry, the profile of ionic actuation, and the physical parameters of the actuator. Examples are shown considering a 3D model of a neuronal soma and a planar ionic actuator. Conclusion. These efforts shed light on how neural activity can be shaped by targeting extracellular K+ and represent a first step towards design-oriented studies of ionic actuators.
Social Determinants of Health, Medical-Legal Partnership, Health Equity, Neonatal Outcomes
Creators: name: Mandelbaum, Ava
name: Farhaj, Nikita
name: Haynes, Browning
name: Morrison, Georgia M.
name: Klawetter, Susanne
Publisher: name: Oregon Health and Science University
Year: 2023
Subjects: subject: Social Determinants of Health
subject: Health Equity
subject: Medical-Legal Partnership
subject: Neonatal Outcomes

description: Medical-legal partnerships (MLPs) are collaborations between health and legal professionals that aim to advance health equity by alleviating health-harming legal problems. In 2020, Doernbecher Children’s Hospital (DCH) launched the nation’s first MLP within a neonatal intensive care unit (NICU) and Fetal Therapy Program to address social determinants of health among the youngest and highest-risk patients. This study aimed to characterize the demographics and legal needs of the population served in a NICU-specific MLP.
A Neurophysiological Theory of Animal Ethics
Creators: name: Cameron, Hunter
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: The argument presented in the rest of this paper has two main goals. In Part I, I will argue that Singer's theory is not capable of providing precise enough guidance with regard to what ethical choices we should make in the less obvious and more complex cases. This is, first, because Singer's theory doesn't distinguish between different kinds of interests and their relative moral weight and does not specify which creatures have which interests. And, second, even if we try to make Singer’s theory more precise, under his framework, moral consideration is skewed in favor of creatures with lesser mental capacities because of his low threshold of sentience as the criterion for moral consideration. This can be problematic because a focus on sentience alone can lead to creatures with greater mental capacities receiving the same or even a lesser treatment than the creatures with lesser mental capacities (that result in a diminished ability to hold a particular interest). From the perspective of common sense, the creatures with greater mental capacities thus end up being treated ‘unfairly’.
Next, in Part II, I will propose an alternative to Singer's view that uses neurophysiology as the foundation for establishing a clearer differentiation between creatures' mental capacities, and then uses these new distinctions as a basis for determining how different creatures ought to be treated. My alternative neurophysiological theory of animal ethics offers more precise prescriptions for which capacities matter most for ethical consideration and identifies which particular animals possess these capacities. In doing so, my theory possesses a level of precision
that a theory of ethics needs in order to be useful in practical cases. However, this precision comes at a cost: the neurophysiological theory is based on cutting-edge science which is controversial in many places and downright contradictory in others. Because the science is not firmly established, I take the presentation of the neurophysiological account to be an approximation that is open to change in light of further developments in neuroscientific research. However, I still think it is very important to offer something constructive to the discussion of animal ethics rather than mere criticism of other views. With that said, I will present the scientific evidence that I take to be the most plausible given our current state of affairs, with the caveat that, at any time in the future, this evidence could be modified or even refuted. My ultimate goal, then, is not to provide a definitive account of animal capacities as they relate to ethics, but rather a view that can function as a model for a principled method for determining the kinds of capacities and interests that should be considered important for animal ethics.
Ozone Increases Purinergic Signaling in Airway Epithelial Cells in Both in Vitro and in Vivo Models
Creators: name: German, Zachary
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Background:  Ozone is a significant oxidizing air pollutant that is found above healthy levels throughout the world.  It has been shown that ozone is associated with respiratory morbidity and mortality, however the mechanism by which it works is still not greatly understood.  Methods: Murine studies involving mice with an induced asthmatic phenotype and in vitro studies involving Beas-2B and 16HBE cells were conducted.  Bronchial alveolar lavage fluid (BALF) was collected intratracheally from mice after exposure to either air or ozone.  Apical and basolateral washes were collected from cells after exposure to either ozone or air.Results:  It was shown that ozone can cause a significant increase in ATP signaling in airway epithelial cells on both the apical and basolateral side, which affects the P2X7 receptor on mast cells, causing airway hyperresponsiveness.  In addition, it was shown that the UDP-Glucose-P2Y14 pathway is not likely to be involved in ozone-induced neutrophil inflammation.Conclusions: ATP signaling is believed to be the mechanism by which mast cells are activated in order to facilitate airway hyperresponsiveness.  Airway hyperresponsiveness is a key symptom in asthma attacks, so showing that ozone can activate this response helps elucidate why ozone causes respiratory morbidity.
Conservation of $ζ$ with radiative corrections from heavy field
Creators: name: Tanaka, Takahiro
name: Urakawa, Yuko
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, we address a possible impact of radiative corrections from a heavy scalar field $χ$ on the curvature perturbation $ζ$. Integrating out $χ$, we derive the effective action for $ζ$, which includes the loop corrections of the heavy field $χ$. When the mass of $χ$ is much larger than the Hubble scale $H$, the loop corrections of $χ$ only yield a local contribution to the effective action and hence the effective action simply gives an action for $ζ$ in a single field model, where, as is widely known, $ζ$ is conserved in time after the Hubble crossing time. Meanwhile, when the mass of $χ$ is comparable to $H$, the loop corrections of $χ$ can give a non-local contribution to the effective action. Because of the non-local contribution from $χ$, in general, $ζ$ may not be conserved, even if the classical background trajectory is determined only by the evolution of the inflaton. In this paper, we derive the condition that $ζ$ is conserved in time in the presence of the radiative corrections from $χ$. Namely, we show that when the scaling symmetry, which is a part of the diffeomorphism invariance, is preserved at the quantum level, the loop corrections of the massive field $χ$ do not disturb the constant evolution of $ζ$ at super Hubble scales. In this discussion, we show the Ward-Takahashi identity for the scaling symmetry, which yields a consistency relation for the correlation functions of the massive field $χ$.
description: 27 pages, 1 figure; v2: updated references and minor revisions
A Sensitive High Performance Liquid Chromatography (HPLC) Assay for the Quantification of Doxorubicin Bound to DNA
Creators: name: Lucas, Andrew T.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Doxorubicin, a widely used anticancer agent, exhibits antitumor activity against a wide variety of malignancies. The drug exerts its cytotoxic effects by binding to and intercalating within the DNA of tumor and tissue cells. However, current assays are unable to accurately determine the concentration of intracellular active form of doxorubicin. Thus, we have developed a high performance liquid chromatography (HPLC) methodology in order to quantify the concentrations of doxorubicin that are bound to DNA in tumors and tissues as an intracellular cytotoxic measure of doxorubicin exposure after administration of small molecule and nanoparticle formulations of doxorubicin. The assay uses daunorubicin as an internal standard; liquid-liquid phase extraction to isolate bound drug; a Shimadzu HPLC with fluorescence detection equipped with a Phenomenex Luna C18 (2 um, 2.0 x 100 mm) analytical column; and a gradient mobile phase of 0.1% formic acid in water and acetonitrile. The assay has a lower limit of quantification (LLOQ) of 10 ng/mL and is shown to be linear up to 3,000 ng/mL. We demonstrated the suitability of this assay for doxorubicin bound to DNA in vivo by using it to quantify the doxorubicin concentration within tumor samples from SKOV3 and HEC1A mice obtained 72 hours after administering PEGylated liposomal doxorubicin (Doxil®; PLD) IV at 6 mg/kg.
This HPLC assay allows for a sensitive and simple intracellular quantification of doxorubicin as compared to other methods and will be an important tool for future studies evaluating intracellular pharmacokinetics of doxorubicin and various nanoparticle carriers.
[Alfred Escher und Tochter Lydia]
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1940
Subjects: Escher, Alfred1819-1882Johann H.Escher vom Glas
Welti-Escher, Lydia1858-1891Lydia WeltiEscher

description: Ganzfigürliches Doppelporträt von Alfred Escher und seine Tochter Lydia im Alter von ca. neun Jahren, vermutlich in einem Fotostudio aufgenommen
description: Anonyme/r Fotograf/in
description: Es handelt sich um eine Fotografie aus dem Jahr ca. 1867, die hier als Fotoreproduktion vorliegt und deren Entstehungsjahr ungesichert ist. Unterhalb des Bildes handschriftlich in schwarzer Feder: "Phot. c. 1867 im Bes. v. Frau Stockar-Breslau"
KELT-10b: The First Transiting Exoplanet from the KELT-South Survey -- A Hot Sub-Jupiter Transiting a V = 10.7 Early G-Star
Creators: name: Kuhn, Rudolf B.
name: Rodriguez, Joseph E.
name: Collins, Karen A.
name: Lund, Michael B.
name: Siverd, Robert J.
name: Colón, Knicole D.
name: Pepper, Joshua
name: Stassun, Keivan G.
name: Cargile, Phillip A.
name: James, David J.
name: Penev, Kaloyan
name: Zhou, George
name: Bayliss, Daniel
name: Tan, T. G.
name: Curtis, Ivan A.
name: Udry, Stephane
name: Segransan, Damien
name: Mawet, Dimitri
name: Soutter, Jack
name: Hart, Rhodes
name: Carter, Brad
name: Gaudi, B. Scott
name: Myers, Gordon
name: Beatty, Thomas G.
name: Eastman, Jason D.
name: Reichart, Daniel E.
name: Haislip, Joshua B.
name: Kielkopf, John
name: Bieryla, Allyson
name: Latham, David W.
name: Jensen, Eric L. N.
name: Oberst, Thomas E.
name: Stevens, Daniel J.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We report the discovery of KELT-10b, the first transiting exoplanet discovered using the KELT-South telescope. KELT-10b is a highly inflated sub-Jupiter mass planet transiting a relatively bright $V = 10.7$ star (TYC 8378-64-1), with T$_{eff}$ = $5948\pm74$ K, $\log{g}$ = $4.319_{-0.030}^{+0.020}$ and [Fe/H] = $0.09_{-0.10}^{+0.11}$, an inferred mass M$_{*}$ = $1.112_{-0.061}^{+0.055}$ M$_{\odot}$ and radius R$_{*}$ = $1.209_{-0.035}^{+0.047}$ R$_{\odot}$. The planet has a radius R$_{P}$ = $1.399_{-0.049}^{+0.069}$ R$_{J}$ and mass M$_{P}$ = $0.679_{-0.038}^{+0.039}$ M$_{J}$. The planet has an eccentricity consistent with zero and a semi-major axis $a$ = $0.05250_{-0.00097}^{+0.00086}$ AU. The best fitting linear ephemeris is $T_{0}$ = 2457066.72045$\pm$0.00027 BJD$_{TDB}$ and P = 4.1662739$\pm$0.0000063 days. This planet joins a group of highly inflated transiting exoplanets with a radius much larger and a mass much less than those of Jupiter. The planet, which boasts deep transits of 1.4%, has a relatively high equilibrium temperature of T$_{eq}$ = $1377_{-23}^{+28}$ K, assuming zero albedo and perfect heat redistribution. KELT-10b receives an estimated insolation of $0.817_{-0.054}^{+0.068}$ $\times$ 10$^9$ erg s$^{-1}$ cm$^{-2}$, which places it far above the insolation threshold above which hot Jupiters exhibit increasing amounts of radius inflation. Evolutionary analysis of the host star suggests that KELT-10b is unlikely to survive beyond the current subgiant phase, due to a concomitant in-spiral of the planet over the next $\sim$1 Gyr. The planet transits a relatively bright star and exhibits the third largest transit depth of all transiting exoplanets with V $
description: 20 pages, 13 figures, 7 tables, accepted for publication in MNRAS
Variance Estimation in Ranked Set Sampling Using a Concomitant Variable
Creators: name: Zamanzade, Ehsan
name: Vock, Michael
Publisher: name: arXiv
Year: 2015
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences
subject: Primary 62D05, Secondary 62G08, 62G05

description: We propose a nonparametric variance estimator when ranked set sampling (RSS) and judgment post stratification (JPS) are applied by measuring a concomitant variable. Our proposed estimator is obtained by conditioning on observed concomitant values and using nonparametric kernel regression.
The Influence of Movement Profile on Measures of Knee Cartilage Health and Body Mass Composition
Creators: name: Dean, Emily
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Purpose: The primary purpose of this study was to evaluate the effects of an individual’s movement profile on body mass composition and knee cartilage health; knee cartilage thickness and quality. The secondary purpose of this study was to determine if there is an association between lean body mass and measures of knee cartilage health. Design: Cross-sectional. Methods: Movement profile was determined using the Landing Error Scoring System (LESS).  Upon completion of the screening, trained LESS raters scored each jump-landing trial to assign the potential study participant into one of two categories: excellent or poor linked to high and low lower extremity injury risk movement profiles. The participant’s height and weight are measured and recorded to later be used in DXA scan for lean body mass analyses. Knee cartilage thickness was determined prior to exercise using an ultrasound of the knee on the subject’s dominant leg completed during knee flexion centered on the intercondylar notch at 145º. Independent samples t-Tests were used to evaluate the effects of movement profile on between movement profile and knee cartilage thickness, and movement profile, total body, and lower extremity lean mass. Pearson-product moment correlations were calculated between lean body mass and knee cartilage health measures.
Results: Movement profile significantly effected lean body mass between movement profile groups. There also seemed to be an inverse relationship between lean muscle mass and cartilage thickness, as well as a positive relationship between movement profile and cartilage water content at rest as measured by musculoskeletal ultrasound. However, there was no significant association between movement profile and knee cartilage thickness. Conclusion: Movement profile influences lean body mass, but alone does not influence cartilage thickness and health measures. There is also a moderate association between lean body mass and measures of cartilage health, including thickness and fluid content levels. Lean mass composition and movement profile have the ability to be altered with training, suggesting that if a person’s biomechanics are improved, their injury risk could be decreased. This could assist in the preservation of cartilage, thus knee joint, health as seen in association between lean body mass and cartilage health measures.
Authorship Patterns in Computer Science Research in the Philippines
Creators: name: Pabico, Jaderick P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Digital Libraries (cs.DL)
subject: FOS: Computer and information sciences

description: We studied patterns of authorship in computer science~(CS) research in the Philippines by using data mining and graph theory techniques on archives of scientific papers presented in the Philippine Computer Science Congresses from 2000 to 2010 involving 326~papers written by 605~authors. We inferred from these archives various graphs namely, a paper--author bipartite graph, a co-authorship graph, and two mixing graphs. Our results show that the scientific articles by Filipino computer scientists were generated at a rate of 33~papers per year, while the papers were written by an average of 2.64~authors (maximum=13). The frequency distribution of the number of authors per paper follows a power-law with a power of $φ=-2.04$ ($R^2=0.71$). The number of Filipino CS researchers increases at an annual rate of 60~new scientists. The researchers have written an average of 1.42~papers (maximum=20) and have collaborated with 3.70~other computer scientists (maximum=54). The frequency distribution of the number of papers per author follows a power law with $φ=-1.88$ ($R^2=0.83$). This distribution closely agrees with Lotka's {\em law of scientific productivity} having $φ\approx -2$. The number of co-authors per author also follows a power-law with $φ=-1.65$ ($R^2=0.80$). These results suggest that most CS~papers in the country were written by scientists who prefer to work alone or at most in small groups. These also suggest that few papers were written by scientists who were involved in large collaboration efforts. The productivity of the Philippines' CS researchers, as measured by their number of papers, is positively correlated with their participation in collaborative research efforts, as measured by their number of co-authors (Pearson $r=0.7425$).
description: 13 pages, 6 figures
Isobaric yield ratio difference between the 140 $A$ MeV $^{58, 64}$Ni + $^{9}$Be reactions studied by antisymmetric molecular dynamics model
Creators: name: Qiao, C. Y.
name: Wei, H. L.
name: Ma, C. W.
name: Zhang, Y. L.
name: Wang, S. S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: \item[Background] The isobaric yield ratio difference (IBD) method is found to be sensitive to the density difference of neutron-rich nucleus induced reaction around the Fermi energy. \item[Purpose] An investigation is performed to study the IBD results in the transport model. \item[Methods] The antisymmetric molecular dynamics (AMD) model plus the sequential decay model GEMINI are adopted to simulate the 140$A$ MeV $^{58, 64}$Ni + $^{9}$Be reactions. A relative small coalescence radius R$_c =$ 2.5 fm is used for the phase space at $t =$ 500 fm/c to form the hot fragment. Two limitations on the impact parameter ($b1 = 0 - 2$ fm and $b2 = 0 - 9$ fm) are used to study the effect of central collisions in IBD. \item[Results] The isobaric yield ratios (IYRs) for the large--$A$ fragments are found to be suppressed in the symmetric reaction. The IBD results for fragments with neutron-excess $I = $ 0 and 1 are obtained. A small difference is found in the IBDs with the $b1$ and $b2$ limitations in the AMD simulated reactions. The IBD with $b1$ and $b2$ are quite similar in the AMD + GEMINI simulated reactions. \item[Conclusions] The IBDs for the $I =$ 0 and 1 chains are mainly determined by the central collisions, which reflects the nuclear density in the core region of the reaction system. The increasing part of the IBD distribution is found due to the difference between the densities in the peripheral collisions of the reactions. The sequential decay process influences the IBD results. The AMD + GEMINI simulation can better reproduce the experimental IBDs than the AMD simulation.
description: 6 pages, 5 figures
Does the CO-to-H2 conversion factor depend on the star formation rate?
Creators: name: Clark, Paul C.
name: Glover, Simon C. O.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a series of numerical simulations that explore how the `X-factor', $X_{CO}$ -- the conversion factor between the observed integrated CO emission and the column density of molecular hydrogen -- varies with the environmental conditions in which a molecular cloud is placed. Our investigation is centred around two environmental conditions in particular: the cosmic ray ionisation rate (CRIR) and the strength of the interstellar radiation field (ISRF). Since both these properties of the interstellar medium have their origins in massive stars, we make the assumption in this paper that both the strength of the ISRF and the CRIR scale linearly with the local star formation rate (SFR). The cloud modelling in this study first involves running numerical simulations that capture the cloud dynamics, as well as the time-dependent chemistry, and ISM heating and cooling. These simulations are then post-processed with a line radiative transfer code to create synthetic 12CO (1-0) emission maps from which $X_{CO}$ can be calculated. We find that for 1e4 solar mass virialised clouds with mean density 100 cm$^{-3}$, $X_{CO}$ is only weakly dependent on the local SFR, varying by a factor of a few over two orders of magnitude in SFR. In contrast, we find that for similar clouds but with masses of 1e5 solar masses, the X-factor will vary by an order of magnitude over the same range in SFR, implying that extra-galactic star formation laws should be viewed with caution. However, for denser ($10^4$ cm$^{-3}$), super-virial clouds such as those found at the centre of the Milky Way, the X-factor is once again independent of the local SFR.
description: 16 pages, 5 figures. Accepted by MNRAS
Coding the Little Particular: A Study of Detail in the Works of Jane Austen
Creators: name: Smith, Emily Carlyle
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: In my initial coding of the little particulars in Sense and Sensibility and Persuasion, I determined that they necessitate and favor certain textual conditions. For example, little particulars are always found in mixed text that incorporates both narrative and dialogue or in reflective dialogue that mirrors these conventions. This is likely due to the fact that little particulars frequently arise in scenes that are grounded in dialogue, but also require the critical eye of a narrator in order to have significance attributed to them. Little particulars also frequently occur when a meaningful and extended change of space occurs within a novel, such as the Dashwoods’ move from Norland to Barton Cottage in Sense and Sensibility. Similarly, little particulars can also predictably be found with the introduction or reintroduction of a character. This is likely due to the fact that each of these events signal change and, thus, necessitate a little particular to bolster the impression of those who are newly encountered. While my initial coding did suggest a certain correlation between little particulars and characters at times of change in the novels, it did not indicate whether or not little particulars were employed for certain types of characters over others. This became a central inquiry for the broader comparative analysis of the novels’ little particulars that followed.