cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cyphoderus bidenticulatus Parona 1888
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Paronellidae
Cyphoderus
Cyphoderus bidenticulatus

description: Cyphoderus bidenticulatus Parona, 1888
– Cyphoderus bidenticulatus Parona, 1888: 63.
KS: Kahrarian 2015; Kahrarian et al. 2016b; LO: Ghavami 2016.
Ecology and habitat in Iran: soil and litter of walnut garden.
General distribution: Palaearctic (Gisin 1960; Buşmachiu 2010; Thibaud 2017; Jakšić et al. 2018).
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 41, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Anurophorus coiffaiti Cassagnau & Delamare 1955
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Anurophorus
Anurophorus coiffaiti

description: Anurophorus coiffaiti Cassagnau & Delamare, 1955
– Anurophorus coiffaiti Cassagnau & Delamare, 1955: 377.
GI: Daghighi 2012; Daghighi et al. 2013a; GO: Falahati et al. 2013b; LO: Moradi et al. 2018, 2019; Kahrarian 2019.
Ecology and habitat in Iran: soil of elm and pomegranate trees.
General distribution: Palaearctic (Daghighi et al. 2013a).
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 41, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Natural Insecticide Pyrethroids Project
Creators: name: Kirichenko, Elmira
name: Kuravsky, Diana
name: Truong, Andrew
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Proposing new regulation and restriction on the advertising statements regarding safety
description: Word “Natural” is very popular today. Every advertisement tries to use it to attract consumers. The average consumer misguided by wording, thinking that it is safe, starts using the insecticides inaccurately as in the example of Amber Nickol published in “‘Safe’ Insecticides Now First in Poisoning” article by M. B. Pell and Jim Morris. The purpose of this project to stop the careless profit makers and to open the eyes of the average consumers showing that “natural” does not nessecerally means safe or harmless. Dose makes the poison even in case of the safest household products. Pyrethroids are a group of synthesized insecticides similar to the natural pesticide pyrethrum, which is produced by chrysanthemum flowers. There is no doubt that pyrethroids are safer than the organophosphate insecticides, but they are not “natural” as media advertises it everywhere and has its own health risks. Modified pyrethroids have the longer half-life compared to the naturally produced pyrethrins and tend to accumulate in the body leading to different health problems. Our task was to search the information about so-called “natural” household insecticides, to interview someone who does the research with pyrethroids in the department of biochemistry and to write the legislative bill including all pros and cons of the topic.
Obesity and Bullying
Creators: name: Williams, Sasha
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Spreading Awareness and Putting a Stop to Bullying for Obese Students
description: Childhood obesity percentages have increased throughout America. More and more children who are obese face the unlawful act of being bullied. Children who are obese and are being bullied, should be aware that there are laws and modes to follow, so they can stop what is happening to them. Most importantly programs should be provided to students with information to decrease bullying in schools. I have created a new program titled “A week of Anti-Bullying,” for schools to implement, to decrease bullying.
A New Target for Lung Cancer Immunotherapy: RNA Editing
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Lung cancer due to long-term smoking accounts for about 25% of all cancer deaths. Cancer immunotherapy involves stimulating the immune system to destroy tumors. It has been shown to be a promising therapeutic avenue for various cancers, including lung cancers. However, it is effective only in a minority of lung cancer patients. The development of approaches to enhance the efficacy of cancer immunotherapy will benefit patients. Recent studies have identified a new target for cancer immunotherapy called, “Adenosine Deaminases Acting on RNA (ADAR)”. It is a protein that binds to RNA and edits the nucleotide content of the RNA to make it unstable. The ADAR gene is highly expressed in many cancer types including lung cancers and removal of it has been shown to inhibit lung tumor cell growth. We plan to study how silencing of the ADAR gene leads to cell growth arrest in many lung cancer cell types. We also plan to test the effect of removal of the ADAR gene on lung cancer immunotherapy in mouse models. The outcome of our study will be to expand our understanding of how ADAR gene functions in lung cancer cells and to provide a new target for lung cancer immunotherapy.
Hippopsis arriagadai Martins & Galileo 2003
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Hippopsis
Hippopsis arriagadai

description: Hippopsis arriagadai Martins & Galileo, 2003
Martins & Galileo, 2003a:28, figs 2, 8.
Holotype ♂, PARAGUAI, Central: Assunción (Arroyo Mburicau), 30.X.1990, G. Arriagada col. (MCNZ 150.085).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 447, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
From Periodontal to Cardiac Disease; Bridging the Gap between Medical and Dental Insurance for a Better Treatment
Creators: name: Yllescas, Sara
name: Radice, Anthony J.
name: Padrino, Javier
name: Liane, Billy-Jo
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Improving health policy by enabling systemic periodontitis patients’ access to enhanced insurance coverage through use of both dental and medical insurance plans.
description: Over the past decade, the association between periodontal disease and cardiac disease has been clinically proven. When the oral originating disease progresses and becomes a systemic disorder, as is the case of advanced periodontal disease patients, their insurance coverage remains exclusively dental. Because periodontal disease is an advanced form of gingivitis that compromises both teeth and gum health, the resulting treatment often requires either an extensive dental coverage plan or a large out-of-pocket payment. This causes much anguish for patients afflicted with periodontal disease since the types of patients that develop this condition are often of a poor economic status and unable to afford treatment. As such, both community awareness and health policy must be improved to get periodontal patients the care that they legally and rightfully deserve. By enforcing medical insurance coverage to be included with the coverage of periodontal disease due to its systemic condition, patients would have access to additional care for a better treatment. Thus, to improve the treatment conditions for current and future periodontal disease patients include increasing community awareness, enforcing inter-insurance collaboration, encouraging legislative involvement, and litigation. As a student group, we went hands on and into our community at a local soup kitchen where we donated both food and dental supplies to the members as well as visitors. We first spoke with patrons about the impacts of periodontal disease, and encouraged each individual to receive a health check-up at a local minimum-pay clinic. This enabled our group to effectively increase community awareness to a group of citizens that are most susceptible to developing periodontal disease. Ultimately, as science continues to define the association between periodontal disease and cardiac disease, patients must be empowered through preventative care and advocated for by holding insurance companies responsible for possible cases of negligence.
Plastic Bottle Bill in New Jersey
Creators: name: Falcone, Samantha
name: Patel, Ankur
name: Patel, Mitesh
name: Siberski, Steve
name: Simon, Melanie
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2010

description: Finding the facts as to why there is no bottle bill in the state of New Jersey, what a bottle bill is composed of, educate people on the effects of the plastic to the earth, and the benefits of a bottle bill.
description: In recent years recycling has become a growing issue. The environment has taken a huge hit with the way people are treating the earth. People have become increasingly less conscious about recycling and the amount of wastes they are producing. With carbon footprints growing larger everyday our group has decided to investigate the reasons behind this growing issue. We focused our concern in the state of New Jersey and it’s reasoning behind not having a bottle bill. The state has taken on rules for recycling, but implementing them has not had a great effort. We spoke with politician, Assemblywoman Valarie Vainieri Huttle, to get to the bottom of this epidemic, while also raising awareness to peers at the Rutgers University campus. What we found was that New Jersey is unsure of how to implement this bill, therefore it is constantly being introduced, but never passed.
Psyllopsis distinguenda Edwards 1913
Creators: name: Burckhardt, Daniel
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Liviidae
Psyllopsis
Psyllopsis distinguenda

description: Psyllopsis distinguenda Edwards, 1913 (Abb. 1c)
Material. Schweiz: BL: 1 ♀, Bubendorf, Wildenstein, 520 m ü. M., 27.6.2002 (R. Mühlethaler leg., NHMB coll.); 2 ♂, Waldenburg, Gerstel, 624290/ 247750, 800 m ü. M., 27.8.2022, Fraxinus excelsior (D. Burckhardt leg., NHMB coll.). BS: 2 ♂, Basel, Lange Erlen, 10.6.2006 (D. Burckhardt leg., NHMB coll.); 3 ♂, 8 ♀, Bettingen, Lauber, 450 m ü. M., 7.6.2000 (D. Wyniger leg., NHMB coll.). UR: 1 ♂, Seedorf, Reussdelta, 689509/ 194054, 440 m ü.M., 6.9.2000, Auenwald, am Licht (L. Rezbanyai-Reser leg., NHMB coll.). – Frankreich: Haut-Rhin: 9 ♂, 4 ♀, St. Louis, Petite Camargue Alsacienne (PCA), Grand Pré, 240 m ü.M., 3.6.2008, Fraxinus excelsior (D. Burckhardt & D. Wyniger leg., NHMB coll.); 5 ♂, 8 ♀, ebenso, aber PCA, Grand Marais, 240 m ü. M., 1.6.2003 (D. Wyniger leg., NHMB coll.).
Psyllopsis distinguenda ist weniger weit verbreitet, aber etwas häufiger als P. discrepans. Lauterer & Eastop (1968) haben die Art aus Grossbritannien, Moldawien, Polen, Rumänien, der Slowakei und der Ukraine (inkl. Krim) gemeldet. Weitere Nachweise stammen aus Belarus (Serbina et al. 2015), Deutschland (Burckhardt & Lauterer 2003), Irland (O’Connor & Malumphy 2011), den Niederlanden (Bieman et al. 2019), der Schweiz (Burckhardt 1994) und Slowenien (Seljak 2020). Aus der Schweiz wurde die Art erstmals von Burckhardt (1983) gemeldet, der zeigte, dass es sich bei den von Schaefer (1949) unter P. discrepans aufgeführten Nachweisen aus BL und VS um P. distinguenda handelt. Weitere Fundstellen in den Kantonen GE, SH, VD und ZH wurden von Burckhardt (1994) publiziert. Hier wird die Art erstmals aus den Kantonen BS und UR sowie aus Frankreich gemeldet, wo sie bisher unbekannt war.
description: Published as part of Burckhardt, Daniel, 2023, Zur Verbreitung von Psyllopsis discrepans, P. distinguenda und Cacopsylla limbata (Hemiptera, Psylloidea) DANIEL BURCKHARDT, pp. 69-76 in Entomo Helvetica 16 on page 72
Anurophorus silvaticus Potapov & Stebaeva 1990
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Anurophorus
Anurophorus silvaticus

description: Anurophorus silvaticus Potapov & Stebaeva, 1990
– Anurophorus silvaticus Potapov & Stebaeva, 1990: 41.
MAZ: Yoosefi Lafooraki et al. 2019, 2020b; Vahedi Moghadam et al. 2022.
Ecology and habitat in Iran: moss on tree, decaying wood and soil.
General distribution: Russia, Caucasus, Azerbaijan and Iran (Potapov 2001).
Genus Folsomia Willem, 1902 (1902b)
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 41, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Hippopsis mourai Martins & Galileo 1994
Creators: name: Groll, Elisa Von
Publisher: name: Zenodo
Year: 2017
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Cerambycidae
Hippopsis
Hippopsis mourai

description: Hippopsis mourai Martins & Galileo, 1994
Martins & Galileo, 1994a:78.
Paratype ♀, BRAZIL, Tocantins: Porto Nacional (Chácara Inferno), 12.XI.1992, Exp. MCN-MZSP col. (MCNZ 233.938).
description: Published as part of Groll, Elisa Von, 2017, Catalogue of Coleoptera type specimens housed in the collection of the Museu de Ciências Naturais, Fundação Zoobotânica do Rio Grande do Sul, Brazil, pp. 439-473 in Zootaxa 4318 (3) on page 447, DOI: 10.11646/zootaxa.4318.3.2, http://zenodo.org/record/887750
State and Local Policies on Cigarette Smoking Behaviors and Disparities
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Cigarette smoking has declined significantly since 1964, but disparities persist across vulnerable populations. Tobacco-related disparities are created and affected by a complex mix of factors: social determinants of health, tobacco industry deliberate promotions, and a lack of comprehensive tobacco control policies at the national and state levels. The majority of health disparity interventions focusing primarily at individual and interpersonal levels have had limited impact on sustained improvements in health behaviors or reductions in health disparities. Until recently, there have been calls for Policy, Systems, and Environmental (PSE) changes to address the risk and protective factors that cut across social and environmental contexts. On April 1, 2017, California’s new cigarette tax rate took effect. Since 1987, cities and counties in California have been at the forefront of adopting local tobacco control policies. Also, California’s smoking landscape is rapidly changing, the e-cigarettes have become the most commonly used tobacco product among Californians. People use e-cigarettes for many reasons, one of the cited reasons is to quit, replace or reduce cigarette smoking.
 This could be the very first study to examine the impact of the state and local policies on smoking behaviors and on reduction of tobacco-related disparities among vulnerable populations. The major outcome measures will be current cigarette smoking (in last 30 days), quit attempts, and use of e-cigarette, especially for the purpose of quitting smoking; as well as the reductions of tobacco-related disparities among vulnerable populations, such as racial/ethnic minorities; low-education or low-income groups, rural residents, sexual/gender minorities (lesbian, Gay, Bisexual, Transgender (LGBT) and others (e.g. those living in multi-unit housing or young adults). The project design addresses multiple levels of policy interventions at the state, county and city-level and their potential interactions, which is novel and important to realize substantial breakthroughs in this area. This research approach is innovative and will provide greater insights into smoking-related disparities and further knowledge on the effects of local and state PSE approaches targeted towards benefiting vulnerable populations.
The role of the NLRP3 inflammasome in e-cigarette-induced cardiac inflammation and remodeling
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Heart failure (HF) is a condition in which the heart can't pump enough blood to meet the body's needs and a leading cause of death worldwide. Cigarette smoking (CS) is an important risk factor for heart failure. Electronic cigarettes (e-cigs) have been on the international market since 2007 and the prevalence of use of e-cigs (such as JUUL) in the United States has rapidly increased, emerging as a public health concern. For instance, the CDC is investigating the ongoing outbreak of e-cigarette or vaping associated lung injury (EVALI).

 Inflammation is the body's response to injury. It works to heal wounds, but it can also play a role in some chronic diseases including HF. The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome is a protein complex that triggers the release of proinflammatory molecules and plays a major role in inflammation. CS is known to induce inflammation but it is not known whether the NLRP3 inflammasome plays a role in e-cig smoking-induced HF. This study tests if inhibition of the NLRP3 inflammasome ameliorates the development of HF induced by e-cig smoking.

 We will first test whether e-cig smoking induces HF and if this is dependent on nicotine. To determine the role of the NLRP3 inflammasome, we will use NLRP3 knockout (KO) mice in which NLRP3 gene is absent. We will also test whether chronic e-cig smoking increases the damage induced by an additional stress. To determine the role of the NLRP3 in heart cells, we will use heart specific NLRP3 KO mice and active mutant NLRP3 expressing mice. Successful completion of this project will demonstrate that NLRP3 plays a critical role in e-cig smoking induced adverse effects on the heart and is thus a potential therapeutic target for e-cig smoking-induced cardiovascular maladies.
Additional file 2: Table S2. of Differences in neurochemical profiles of two gadid species under ocean warming and acidification
Creators: name: Schmidt, Matthias
name: Windisch, Heidrun
name: Kai-Uwe Ludwichowski
name: Seegert, Sean
name: Hans-Otto Pörtner
name: Storch, Daniela
name: Bock, Christian
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry

description: Protocol depicting the buffer composition throughout HPLC-analysis. Total measurement time per sample was 90 min. The first column shows the time for onset of the respective composition. (DOCX 11 kb)
The effect of E-cigarettes on tongue epithelium and taste bud regeneration
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: The adult mammalian tongue (lingual) epithelium is continuously rapidly renewing. Pools of basally located lingual progenitors constantly give rise to taste and non-taste cells. Taste is one of the basic senses. The chemical stimuli transferred from gustatory organs to the brain contain information about ingested materials. Taste buds are not only sensors of nutrients, they can also trigger central reward systems. Such sensations have led to an industry of food flavorings, and more recently have been taken advantage by companies making E-cigarettes (E-cigs). The use of E-cigs has greatly increased beyond its initial marketing goal of helping smokers quit, and they especially appeal to youth, mainly due to the extensive variety of flavor options. E-cigs, similarly to regular cigarettes, are designed to deliver nicotine via aerosols. A host of studies have shown that E-cig use is associated with adverse effects, including increased inflammation and oral diseases, despite the fact that unburned tobacco contains fewer carcinogens than cigarette smoke. The overarching goal of this proposal is to unravel the direct effects of E-cigs on lingual epithelium regeneration and differentiation capacities. This project is of great clinical importance, as it will enable the characterization of targets for prevention or treatment of oral pathologies.
Additional file 1: Table S1. of Molecular typing of Trichomonas vaginalis isolates by actin gene sequence analysis and carriage of T. vaginalis viruses
Creators: name: Masha, Simon
name: Cools, Piet
name: Crucitti, Tania
name: Sanders, Eduard
name: Vaneechoutte, Mario
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Genotype, number and position of restriction sites using HindII, MseI and RsaI restriction enzymes for actin sequences retrieved from GenBank. (DOCX 15Â kb)
Folsomia asiatica Martynova 1971
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Folsomia
Folsomia asiatica

description: Folsomia asiatica Martynova, 1971
– Folsomia asiatica Martynova, 1971: 602.
KS: Amiri & Kahrarian 2015; Arbea & Kahrarian 2015b; LO: Ahmadi-Rad & Kahrarian 2015; GO: Yoosefi Lafooraki et al. 2020b.
Ecology and habitat in Iran: leaf litter under walnut orchards and oak forest.
General distribution: Tajikistan and Azerbaijan (Potapov 2001) and Iran.
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 41, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Investigation of neural ensembles underlying nicotine withdrawal-induced hyperalgesia
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Smoking is the leading cause of preventable death in the United States. Nearly 14 out of every 100 American adults are current cigarette smokers, according to a 2018 report from the Centers for Disease Control and Prevention (CDC). More than 16 million Americans are afflicted with a smoking-related disease - which may include cancer, lung disease, diabetes, and heart disease. The high proportion of people who continue to smoke despite living with these disabilities reflects how dangerously addictive cigarettes can be. Smoking’s addictive nature stems from the actions of nicotine, the primary psychoactive ingredient in cigarettes. Nicotine alters neuronal communication and the release of dopamine and noradrenaline, chemical messengers in the brain that can effect changes in mood and focus, creating a “smoker’s high”. In the absence of nicotine, users increasingly crave this “smoker’s high”, making attempts to quit long-term difficult. In addition, nicotine withdrawal causes several negative symptoms, including increased anxiety and sensitivity to pain, among others. Whereas much of the current research to help smokers quit focuses on dampening the rewarding aspects of nicotine, less efforts have been made to understand and mitigate the negative aspects of withdrawal. In this proposal, I plan to use innovative whole-brain imaging, viral-genetic techniques, and classical behavioral assays to understand how long-term nicotine use can create changes in the brain that alter the pain experience.
Exploring DNA Polymerase Eta as a Target to Overcome the Resistance to Platinum-based Drugs in NSCLC
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Lung cancer, primarily caused by tobacco exposure, is the leading cause of cancer-related mortality. There are two main types of lung cancer: non-small cell lung cancer (NSCLC) accounting for 85% of lung cancers, and small cell lung cancer (~15%). Currently, platinum-based chemotherapy are used as the standard of care for most advanced NSCLC. However, the efficacy of chemotherapy is often limited due to rapid acquisition of drug resistance. Thus, understanding the mechanism of drug resistance would be helpful for the development of novel strategies to overcome chemoresistance in NSCLC. In this regard, we investigated the role of DNA polymerase eta (PolH), a low fidelity DNA polymerase, in cisplatin resistance. PolH bypasses DNA lesions through incorporation of wrong nucleotides and thus, helps tumor cells tolerate DNA damage response at the expense of potential mutations. Indeed, we found that high expression of PolH is associated with cisplatin resistance in NSCLC and targeting PolH sensitizes NSCLC cells to cisplatin treatment. Interestingly, we also found that PolH suppressed wild-type p53 expression but enhanced mutant p53 expression. Tumor suppressor p53 is frequently mutated in lung cancer and mutant p53 is known to be associated with chemoresistance in NSCLC. Thus, we hypothesizes that PolH confers cisplatin resistance by differentially regulating wild-type vs mutant p53, which can be explored for overcoming chemoresistance in NSCLC. To test this, we will determine the mechanism by which PolH differentially regulates wild type vs mutant p53. We will also evaluate the therapeutic potential of targeting the PolH-wild type p53 and PolH-mutant p53 pathways to overcome cisplatin resistance in NSCLC. Successful completion of this project would further our understanding of the mechanism of chemoresistance, which may be used for the development of novel therapeutic approaches to overcome cisplatin resistance in NSCLC. Moreover, the research findings from this project will be presented at the First-Year Seminars or Quit Tobacco classes at UC Davis. The P.I. will discuss with the general audience about how smoke causes cancer from a scientific point of view. By these means, we hope that we can develop a positive attitude to help smokers quit smoking and assist non-smokers to motivate other people, such as family members or friends, to quit smoking.
MOESM1 of Vision-assisted micromanipulation using closed-loop actuation of multiple microrobots
Creators: name: M. Rahman
name: Takahashi, Noboru
name: Kawai Siliga
name: Ng, Nigel
name: Zhidong Wang
name: Ohta, Aaron
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Â Supplementary information.
Chemistry of freshly-emitted vaping aerosols: Implications for exposure, uptake and health
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Understanding the chemistry of freshly-emitted vaping aerosols is critically needed to address the youth vaping epidemic, driven by products like JUUL, and the deadly outbreak of e-cigarette or vaping-associated acute lung injury (EVALI). The proposed research intends to elucidate chemical interactions within freshly generated aerosol particles, under conditions that are relevant to vaping. These include molecular associations and formation of ultrafine particles carrying high molecular weight constituents. The approach will combine state-of-the-art techniques using an Advanced Light Source (ALS) with traditional environmental and analytical chemistry tools. Results will be used to predict user’s uptake, non-users’ exposure risks, and potential health impacts.

 Benzoic acid is used in JUUL e-liquids at levels comparable to nicotine. This additive makes the liquid less harsh upon inhalation, thus enabling formulations containing 3 to 6 times higher nicotine levels than most e-liquids. Similarly, menthol is used at relatively high concentrations, often comparable to nicotine. It is associated with the “impact” upon inhalation, strength and satisfaction, all of which reinforce smoking behavior. To better understand the effects attributed to benzoic acid and menthol, we intend to reveal their chemical interactions with nicotine in aerosols shortly after the particles are produced. This is the most relevant time scale for user’s uptake and secondhand exposures. We will determine the effect of additives on different e-liquid formulations, to identify the most important mechanisms for nicotine delivery to the lung, and impacts on the indoor environment.

 The proposed research will also explore the role of ultra fine particles as carriers of high-molecular weight compounds present in dual use nicotine/cannabis vaping products, as vehicles of their delivery to the lung and into indoor environments. Tested compounds will include vitamin E acetate, which was recently associated with EVALI. We will also investigate generation of methacrolein and other harmful compounds produced in thermal decomposition of cannabis formulations. Results will be used as inputs in models that estimate daily intake in typical scenarios. The predicted toxicant doses will be compared with health-based criteria, to assess potential risks.
Folsomia binoculata
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Folsomia
Folsomia binoculata

description: Folsomia binoculata (Wahlgren, 1899)
– Isotoma binoculata Wahlgren, 1899: 338.
KS: Ghahramaninezhad et al. 2013; IL: Bazgir & Mirab-balou 2019.
Ecology and habitat in Iran: soil and leaf litter.
General distribution: Palaearctic (arctic islands and Taimyr) (Fjellberg 2007) and Iran.
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 42, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
Comprehensive plan report, Bergen County New Jersey open space and recreation inventory; Report no. 26, February, 19&5
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1975

description: Analysis of open space and recreation facilities in the county, including roles of government and county responsibilities; factors influencing recreation demand; public recreation and open space resources; educational recreation resources; private recreation facilities; public recreation facilities and public park and open space acquisition.
Rusa alfredi
Creators: name: Don E. Wilson
name: Russell A. Mittermeier
Publisher: name: Lynx Edicions
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Mammalia
Artiodactyla
Cervidae
Rusa
Rusa alfredi

description: 21.
Philippine Spotted Deer
Rusa alfredi
French: Cerf d'Alfred / German: Prinz-Alfred-Hirsch / Spanish: Sambar manchado de Filipinas
Other common names: Prince Alfred's Sambar, Visayan Spotted Deer
Taxonomy. Cervus alfredi Sclater, 1870,
Philippines.
This species has been treated for decades as a dwarf island form of R. unicolor. The scientific name refers to Prince Alfred, son of Queen Victoria, who sent a specimen to P. L. Sclater. Monotypic.
Distribution. Panay and Negros Is, in W Visayas, Philippines.
Descriptive notes. Head-body 130 cm, tail 12 cm, shoulder height 65-75 cm; weight of males around 40 kg. Small to medium-sized deer with a narrow skull and pointed face. Ears relatively small. Fur fine, soft, and dense. The coat is dark brown with beige and whitish spots and a blackish spinal band. Head and neck darker, underparts cream. White on chin and lowerlip. Antlers of adults three-tined and 25 cm in lenght.
Habitat. It is now restricted to steep slopes of dipterocarp forests.
Food and Feeding. It feeds on leaves, buds, forbs, young grasses, and fruits.
Breeding. Females attain puberty at about twelve months of age. Breeding occurs all year. Mating season peaks in November-December, births in May-June. Gestation is around 240 days. Females give birth to a single fawn.
Activity patterns. Mainly nocturnal.
Movements, Home range and Social organization. It is not very social, with males mostly solitary and females with their fawns.
Status and Conservation. Classified as Endangered on The IUCN Red List. Hunting and logging for plantations and agriculture have drastically fragmented its range and decreased its population.
Bibliography. Cox (1987), Grubb & Groves (1983), Oliver et al. (1991).
description: Published as part of Don E. Wilson & Russell A. Mittermeier, 2011, Cervidae, pp. 350-443 in Handbook of the Mammals of the World – Volume 2 Hoofed Mammals, Barcelona :Lynx Edicions on page 418, DOI: 10.5281/zenodo.6514377
Additional file 1: Table S1. of Molecular typing of Trichomonas vaginalis isolates by actin gene sequence analysis and carriage of T. vaginalis viruses
Creators: name: Masha, Simon
name: Cools, Piet
name: Crucitti, Tania
name: Sanders, Eduard
name: Vaneechoutte, Mario
Publisher: name: Figshare
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Genotype, number and position of restriction sites using HindII, MseI and RsaI restriction enzymes for actin sequences retrieved from GenBank. (DOCX 15Â kb)
Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation among Cancer Patients
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: "It's never too late to quit smoking," despite mounting evidence showing benefits of stopping smoking after cancer diagnosis, less than one in five cancer patients have received assistance from their oncologists for stopping smoking. Initiating radiation therapy (RT) is an opportune time to engage cancer patients to quit smoking. The purpose of this study is to develop an interactive patient education tool to more effectively engage cancer patients in the context of receiving RT to promote patient-provider discussion, referral to smoking cessation resources, and smoking cessation among cancer patients treated with RT. Our team has developed and tested various versions of a patient education tool, the interactive Mobile Doctor (iMD) that delivers the “5 A’s” via interactive videos in prenatal care, primary care and most recently lung cancer screening. iMD asks about smoking status; advises quitting; assesses readiness to quit; assists concerns about quitting with cessation resources information; and arranges follow-up by generating a tailored printout to enhance patient-provider discussion on tobacco use. Findings across multiple trials have supported the feasibility and acceptability of the iMD in promoting patient-provider discussion of tobacco use and smoking reduction and cessation outcomes. Our most recently completed randomized controlled trial with 174 daily smokers at primary care clinics of a federally qualified health center has shown that patients receiving iMD before seeing their physicians were more likely to report having a discussion on tobacco with their provider at the visit and reported higher satisfaction with the discussion they had with their providers on tobacco, when compared to others who received a video education on nutrition and physical activity. At 6-month follow-up, an iMD participants were more likely to report a 7-day smoking abstinence. Leveraging our multidisciplinary team’s experience in radiation oncology, oncology nursing, clinical pharmacy, primary care, smoking cessation treatment and in developing interactive patient education tools, we propose to develop and conduct a feasibility test of a iMD intervention utilizing patient-centered and interactive technology approaches to target 80 cancer patients being treated with RT to promote smoking cessation and maintaining abstinence during and post completion of RT.
MOESM1 of Vision-assisted micromanipulation using closed-loop actuation of multiple microrobots
Creators: name: M. Rahman
name: Takahashi, Noboru
name: Kawai Siliga
name: Ng, Nigel
name: Zhidong Wang
name: Ohta, Aaron
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Â Supplementary information.
Wharton Borough Morris County New Jersey preliminary master plan studies, proposed land use plan, March 1959
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1959

description: The purpose of the Land Use Plan is to help establish a pattern of community development for the future. Essentially the plan is a system of objectives in mapped form, designed to make explicit the Borough's basic land use policies as developed by the local planning board with the aid of detailed planning studies and professional planning advice. The proposals are intended to be broad in scope and should illustrate basic concepts. The specific controls which are to be derived from the plan will show up in the Zoning and Subdivision Ordinances and on the Official Map, which spell out in detail how the broad objectives are to be achieved. While the Zoning Ordinance and Official Map will not and in some instances should not immediately reflect all of the objectives of the plan it is expected that gradual changes will be made over a period of years which will bring the controls and the plan into closer harmony.
Planning report for Woodbury
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1953

description: This Planning Report for Woodbury represents what may be characterized as a preliminary analytical inventory of community resources, prospects, and problems in relation to the Greater Philadelphia-South Jersey Region and Gloucester County. It is intended not only to indicate the scope and approach of the City Planning Program to officials and citizens alike, but also to summarize the substance of planning studies carried out thus far for the information of am use by City Council, the School Board, other public authorities, and private groups and agencies.
Understanding Genetic Interactions in the p53 Network in Lung Adenocarcinoma Suppression
Creators: name: University Of California Office Of The President
Publisher: name: University of California Office of the President
publisherIdentifier: https://ror.org/00dmfq477
publisherIdentifierScheme: ROR
Year: 2024

description: Cells have genes called tumor suppressors to prevent the uncontrolled tissue growth that can result in cancer. One of the most important tumor suppressors is called p53. p53 normally blocks cells from growing into tumors, but when the p53 gene is damaged, for example when tobacco chemicals cause it to mutate, it cannot block tumor formation. We know from the DNA from lung cancer patients that mutations in p53 are common in tumors, unmistakably linked to smoking, and detrimental for survival. Normally, p53 activates many other genes in cells, and studies have shown that this gene-activating function is essential to p53 preventing cancer. Importantly, damaged or mutant p53 cannot perform this function. I seek to understand what p53 normally does in cells to prevent cancer by studying the genes it normally activates and identifying those that are most important for blocking tumor growth, specifically in lung cancer. My preliminary studies in mouse cells suggest that pairs of these p53-activated genes work together to prevent tumor growth. In this project, I will test if these pairs of p53-activated genes can work together to suppress lung cancer, as I predict.

 Although mouse studies have led to powerful insights into cancer, there can be differences between the way genes work in mice versus humans. Therefore, I will use samples from human cancer patients to first confirm that the genes I study in mice are controlled by p53 in human lung cancer by measuring how active the genes are in samples that have functioning p53 versus mutated p53 to ensure my studies are relevant to lung cancer patients. I will then study the impact of p53-activated genes in altering the growth of cells and the growth of tumors in a mouse model of lung cancer by using tools to turn these genes on or off in pairs. I predict that turning pairs of these genes off in lung cancer will promote cancer growth, suggesting that these genes normally oppose cancer and that I have found at least part of how p53 works to prevent cancer. I will then study what these genes do in cells that makes them block cancer growth. Once we understand what these genes do, my project may inform the design of therapies to help lung cancer patients and will give us a better understanding of why p53 is such an important tumor suppressor.
A master plan for Wildwood Crest
Creators: name: No Name Supplied
Publisher: name: No Publisher Supplied
Year: 1960

description: A Master Plan for Wildwood Crest is a guide for the future development of the Borough. Its major goals and principles are for the welfare of those who reside there today and in the future.The Master Plan should fotlow three basic principles in order to perform its intended purpose. It must be long range, comprehensive, and general.To be "long range" is to think ahead for varying periods of time, for ten, twenty or thirty years. This farsighted thinking can only be founded upon goals for the future, goals based upon present conditions, trends, and desires.  The following represent goals established in developing the Wildwood Crest Master Plan:(1) To guide the future development of the Borough through coordinated and harmonious future land use.(2) To encourage a social, economic, political, and physical center in the Borough.(3) To allow a future population of such size that can be adequately furnished with community facilities and services.(4) To increase the ease of traffic circulation within the Borough.(5) To encourage a system of schools which would be within walking distance with ease and safety to children.(6) To provide all areas of the community with easily accessible recreation facilities for all ages.(&) To provide municipal facilities to underdeveloped areas within the Borough.(8) To broaden the Borough tax base through the encouragement business and motel development in accordance with zoning and other standards and to maintain the residential character of Wildwood Crest.To be comprehensive, the Master Plan must include a!l geographic, as well as functional areas. lt must consider the type and intensity of desired future land use. It must consider to what extent municipal services and facilities will need expansion and decide their future location. It must consider not only physical growth, but the economic and socialeffects of this growth. It must integrate these parts into one plan or guide for the future. Although the Moster Plan deals with all phases of community growth, it must organize them in a general fashion, a fashion that is both flexible and adoptable to necessary future changes. A plan so rigid that it cannot incorporate these changes will soon become obsolete and worthless. For this reason, the Master Plan must be continually the subiect of review and revision by the Planning Board.These, then, are the basic goals, obiectives and principles that have guided the preparation of "A Master Plan for Wildwood Crest." They are essential not only to the proper formulation of the Master Plan, but form an important part of the very foundations of the modern planning process.
Folsomia brevifurca
Creators: name: Mayvan, Mahmood Mehrafrooz
name: Greenslade, Penelope
name: Sadeghi-Namaghi, Hussein
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Collembola
Entomobryomorpha
Isotomidae
Folsomia
Folsomia brevifurca

description: Folsomia brevifurca (Bagnall, 1949)
– Litsteria brevifurca Bagnall, 1949d: 61.
MAZ: Cox 1982.
Ecology and habitat in Iran: soil and leaf litter.
General distribution: Palaearctic (Dányi & Traser 2008).
description: Published as part of Mayvan, Mahmood Mehrafrooz, Greenslade, Penelope & Sadeghi-Namaghi, Hussein, 2023, An annotated checklist of the Collembola (Hexapoda) from Iran, pp. 1-101 in Zootaxa 5275 (1) on page 42, DOI: 10.11646/zootaxa.5275.1.1, http://zenodo.org/record/7898948
MA'NAVIY EHTIYOJLAR SHAKLLANISHIDA ZAMONAVIY AXBOROT KOMMUNIKATSIYALARINING O`RNI
Creators: name: Jabborov, Jamshid
name: Norsubxonova, Dilshoda
Publisher: name: Zenodo
Year: 2025

description: Jamiyat sohalaridagi yangiliklar, ixtirolar, yutuqlar butun insoniyatning mulkiga aylanmoqda. Bugungi kunda har qanday ahamiyatli, qiziq g‘oyalarning, foydali va foydasiz axborotning, texnologiyalarning, mahsulotlarning dunyo bo‘ylab tez tarqalishiga guvoh bo‘lmoqdamiz.