cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Methodology for adaptive and robust FDG-PET escalated dose painting by numbers in head and neck tumors
Creators: name: Differding, Sarah
name: Sterpin, Edmond
name: Janssens, Guillaume
name: François-Xavier Hanin
name: Lee, John Aldo
name: Grégoire, Vincent
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Cancer
Biological Sciences
Chemistry
Pharmacology
Cell Biology
Medicine
Physics
Engineering

description: Objective. To develop a methodology for using FDG PET/CT in adaptive dose painting by numbers (DPBN) in head and neck squamous cell carcinoma (HNSCC) patients. Issues related to noise in PET and treatment robustness against geometric errors are addressed.Methods. Five patients with locally advanced HNSCC scheduled for chemo-radiotherapy were imaged with FDG-PET/CT at baseline and 2–3 times during radiotherapy (RT). The GTVPET was segmented with a gradient-based method. A double median filter reduces the impact of noise in the PET uptake-to-dose conversion. Filtered FDG uptake values were linearly converted into a voxel-by-voxel prescription from 70 (median uptake) to 86 Gy (highest uptake). A PTVPET was obtained by applying a dilation of 2.5 mm to the entire prescription. Seven iso-uptake thresholds led to seven sub-levels compatible with the Tomotherapy HiArt® Treatment Planning System. Planning aimed to deliver a median dose of 56 Gy and 70 Gy in 35 fractions on the elective and therapeutic PTVs, respectively. Plan quality was assessed with quality volume histogram (QVH). At each time point, plans were generated with a total of 3–4 plans for each patient. Deformable image registration was used for automatic contour propagation and dose summation of the 3 or 4 treatment plans (MIMvista®).Results. GTVPET segmentations were performed successfully until week 2 of RT but failed in two patients at week 3. QVH analysis showed high conformity for all plans (mean VQ = 0.95 93%; mean VQ = 1.05 3.9%; mean QF 2.2%). Good OAR sparing was achieved while keeping high plan quality.Conclusion. Our results show that adaptive FDG-PET-based escalated dose painting in patients with locally advanced HNSCC is feasible while respecting strict dose constraints to organs at risk. Clinical studies must be conducted to evaluate toxicities and tumor response of such a strategy.
Are energy drinks unique mixers in terms of their effects on alcohol consumption and negative alcohol-related consequences?
Creators: name: Johnson, Sean J.
name: Alford, Chris
name: Stewart, Karina
name: Verster, Joris
Publisher: name: Swinburne
Year: 2024

description: Introduction: Previous research has suggested that consuming alcohol mixed with energy drinks (AMED) increases overall alcohol consumption. However, there is limited research examining whether energy drinks are unique in their effects when mixed with alcohol, when compared with alcohol mixed with other caffeinated mixers (AOCM). Therefore, the aim of this survey was to investigate alcohol consumption on AMED occasions, to that on other occasions when the same individuals consumed AOCM or alcohol only (AO).
Methods: A UK-wide online student survey collected data on the frequency of alcohol consumption and quantity consumed, as well as the number of negative alcohol-related consequences reported on AO, AMED and AOCM occasions (N=250).
Results: Within-subjects analysis revealed that there were no significant differences in the number of alcoholic drinks consumed on a standard and a heavy drinking session between AMED and AOCM drinking occasions. However, the number of standard mixers typically consumed was significantly lower on AMED occasions compared with AOCM occasions. In addition, when consuming AMED, students reported significantly fewer days consuming 5 or more alcohol drinks, fewer days mixing drinks, and fewer days being drunk, compared with when consuming AOCM. There were no significant differences in the number of reported negative alcohol-related consequences on AMED occasions to AOCM occasions. Of importance, alcohol consumption and negative alcohol-related consequences were significantly less on both AMED and AOCM occasions compared with AO occasions.
Conclusion: The findings that heavy alcohol consumption occurs significantly less often on AMED occasions compared with AOCM occasions is in opposition to some earlier claims implying that greatest alcohol consumption occurs with AMED. The overall greatest alcohol consumption and associated negative consequences were clearly associated with AO occasions. Negative consequences for AMED and AOCM drinking occasions were similar, suggesting that energy drink was comparable with AOCM in this regard.
Knowledge, Attitude and Practices of Mothers on Child Routine Immunization in       Hargaisa, Somalia,2023
Creators: name: Mahad, Abukar Hussein
Publisher: name: Zenodo
Year: 2025
Subjects: Knowledge, Attitude
Practices of Mothers on Child Routine Immunization

description: Abstract

Routine immunization (RI) plays a crucial role in protecting individuals from vaccine-preventable diseases. It involves the consistent and timely administration of vaccines to ensure that every person is fully immunized (WHO, 2018).
Substrate adhesion regulates sealing zone architecture and dynamics in cultured osteoclasts
Creators: name: Anderegg, Fabian
name: Geblinger, Dafna
name: Horvath, Peter
name: Charnley, Mirren
name: Textor, Marcus
name: Addadi, Lia
name: Geiger, Benjamin
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 310105
subject: Cellular interactions (incl. adhesion, matrix, cell wall)

description: The bone-degrading activity of osteoclasts depends on the formation of a cytoskeletal-adhesive super-structure known as the sealing zone (SZ). The SZ is a dynamic structure, consisting of a condensed array of podosomes, the elementary adhesion-mediating structures of osteoclasts, interconnected by F-actin filaments. The molecular composition and structure of the SZ were extensively investigated, yet despite its major importance for bone formation and remodelling, the mechanisms underlying its assembly and dynamics are still poorly understood. Here we determine the relations between matrix adhesiveness and the formation, stability and expansion of the SZ. By growing differentiated osteoclasts on micro-patterned glass substrates, where adhesive areas are separated by non-adhesive PLL-g-PEG barriers, we show that SZ growth and fusion strictly depend on the continuity of substrate adhesiveness, at the micrometer scale. We present a possible model for the role of mechanical forces in SZ formation and reorganization, inspired by the current data.
Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responses
Creators: name: Hakanson, Maria
name: Kobel, Stefan
name: Lutolf, Matthias P.
name: Textor, Marcus
name: Cukierman, Edna
name: Charnley, Mirren
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 310102
subject: Cell development, proliferation and death

description: Background: Increasing evidence shows that the cancer microenvironment affects both tumorigenesis and the response of cancer to drug treatment. Therefore in vitro models that selectively reflect characteristics of the in vivo environment are greatly needed. Current methods allow us to screen the effect of extrinsic parameters such as matrix composition and to model the complex and three-dimensional (3D) cancer environment. However, 3D models that reflect characteristics of the in vivo environment are typically too complex and do not allow the separation of discrete extrinsic parameters. Methodology/Principal Findings: In this study we used a poly(ethylene glycol) (PEG) hydrogel-based microwell array to model breast cancer cell behavior in multilayer cell clusters that allows a rigorous control of the environment. The innovative array fabrication enables different matrix proteins to be integrated into the bottom surface of microwells. Thereby, extrinsic parameters including dimensionality, type of matrix coating and the extent of cell-cell adhesion could be independently studied. Our results suggest that cell to matrix interactions and increased cell-cell adhesion, at high cell density, induce independent effects on the response to Taxol in multilayer breast cancer cell clusters. In addition, comparing the levels of apoptosis and proliferation revealed that drug resistance mediated by cell-cell adhesion can be related to altered cell cycle regulation. Conversely, the matrix-dependent response to Taxol did not correlate with proliferation changes suggesting that cell death inhibition may be responsible for this effect. Conclusions/Significance: The application of the PEG hydrogel platform provided novel insight into the independent role of extrinsic parameters controlling drug response. The presented platform may not only become a useful tool for basic research related to the role of the cancer microenvironment but could also serve as a complementary platform for in vitro drug development.
Methodology for adaptive and robust FDG-PET escalated dose painting by numbers in head and neck tumors
Creators: name: Differding, Sarah
name: Sterpin, Edmond
name: Janssens, Guillaume
name: François-Xavier Hanin
name: Lee, John Aldo
name: Grégoire, Vincent
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective. To develop a methodology for using FDG PET/CT in adaptive dose painting by numbers (DPBN) in head and neck squamous cell carcinoma (HNSCC) patients. Issues related to noise in PET and treatment robustness against geometric errors are addressed. Methods. Five patients with locally advanced HNSCC scheduled for chemo-radiotherapy were imaged with FDG-PET/CT at baseline and 2–3 times during radiotherapy (RT). The GTVPET was segmented with a gradient-based method. A double median filter reduces the impact of noise in the PET uptake-to-dose conversion. Filtered FDG uptake values were linearly converted into a voxel-by-voxel prescription from 70 (median uptake) to 86 Gy (highest uptake). A PTVPET was obtained by applying a dilation of 2.5 mm to the entire prescription. Seven iso-uptake thresholds led to seven sub-levels compatible with the Tomotherapy HiArt® Treatment Planning System. Planning aimed to deliver a median dose of 56 Gy and 70 Gy in 35 fractions on the elective and therapeutic PTVs, respectively. Plan quality was assessed with quality volume histogram (QVH). At each time point, plans were generated with a total of 3–4 plans for each patient. Deformable image registration was used for automatic contour propagation and dose summation of the 3 or 4 treatment plans (MIMvista®). Results. GTVPET segmentations were performed successfully until week 2 of RT but failed in two patients at week 3. QVH analysis showed high conformity for all plans (mean VQ = 0.95 93%; mean VQ = 1.05 3.9%; mean QF 2.2%). Good OAR sparing was achieved while keeping high plan quality. Conclusion. Our results show that adaptive FDG-PET-based escalated dose painting in patients with locally advanced HNSCC is feasible while respecting strict dose constraints to organs at risk. Clinical studies must be conducted to evaluate toxicities and tumor response of such a strategy.
Concurrent Negotiation over Quality of Service
Creators: name: Mansour, Khalid
name: Kowalczyk, Ryszard
name: Wosko, Michal
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 460206
subject: Knowledge representation and reasoning
classificationCode: 460299
subject: Artificial intelligence not elsewhere classified

description: This paper addresses the problem of flexible procurement of multiple services with multiple non-functional characteristics, i.e., quality of service attributes. We consider the one-to-many negotiation approach as a flexible method for procuring multiple services by a buyer agent. We address the problem of coordinating multiple concurrent negotiations and propose a novel dynamic negotiation strategy that considers the behaviors of the opponents of the current negotiation encounter in managing the local reservation values of the common negotiation issues (attributes) of different services. Most previous works consider the problem of negotiation over a single issue. We investigate a more complex situation where a buyer agent negotiates over multiple services given that each service has multiple negotiation issues. The experimental results show an evidence for the effectiveness and robustness of our dynamic negotiation strategy in various negotiation environments.
Methodology for adaptive and robust FDG-PET escalated dose painting by numbers in head and neck tumors
Creators: name: Differding, Sarah
name: Sterpin, Edmond
name: Janssens, Guillaume
name: François-Xavier Hanin
name: Lee, John Aldo
name: Grégoire, Vincent
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective. To develop a methodology for using FDG PET/CT in adaptive dose painting by numbers (DPBN) in head and neck squamous cell carcinoma (HNSCC) patients. Issues related to noise in PET and treatment robustness against geometric errors are addressed. Methods. Five patients with locally advanced HNSCC scheduled for chemo-radiotherapy were imaged with FDG-PET/CT at baseline and 2–3 times during radiotherapy (RT). The GTVPET was segmented with a gradient-based method. A double median filter reduces the impact of noise in the PET uptake-to-dose conversion. Filtered FDG uptake values were linearly converted into a voxel-by-voxel prescription from 70 (median uptake) to 86 Gy (highest uptake). A PTVPET was obtained by applying a dilation of 2.5 mm to the entire prescription. Seven iso-uptake thresholds led to seven sub-levels compatible with the Tomotherapy HiArt® Treatment Planning System. Planning aimed to deliver a median dose of 56 Gy and 70 Gy in 35 fractions on the elective and therapeutic PTVs, respectively. Plan quality was assessed with quality volume histogram (QVH). At each time point, plans were generated with a total of 3–4 plans for each patient. Deformable image registration was used for automatic contour propagation and dose summation of the 3 or 4 treatment plans (MIMvista®). Results. GTVPET segmentations were performed successfully until week 2 of RT but failed in two patients at week 3. QVH analysis showed high conformity for all plans (mean VQ = 0.95 93%; mean VQ = 1.05 3.9%; mean QF 2.2%). Good OAR sparing was achieved while keeping high plan quality. Conclusion. Our results show that adaptive FDG-PET-based escalated dose painting in patients with locally advanced HNSCC is feasible while respecting strict dose constraints to organs at risk. Clinical studies must be conducted to evaluate toxicities and tumor response of such a strategy.
Surnaming Children Born to Lesbian and Heterosexual Couples: Displaying Family Legitimacy to Diverse Audiences
Creators: name: Dempsey, Deborah
name: Lindsay, Jo
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 4410
subject: Sociology
subject: FOS: Sociology

description: Surnaming practices are a case study of change and continuity in patrilineal conventions in families and also alert us to the challenges of negotiating familial identities in an era of family diversity. Using data from two Australian sources, 430,753 Victorian birth registrations and 43 in-depth interviews with heterosexual and lesbian parents, we explore continuity and breaks with convention in surnaming children. For married and unmarried heterosexual couples, the dominant surnaming practice was for children to take their father’s name. By contrast, several surnaming strategies were more popular among lesbian couples including: using hyphenated or double-barrelled surnames, using the birth or non-birth mother’s surname or creating a new name for the family. Despite these differences, we contend that through their surnaming decisions both lesbian and heterosexual couples are concerned with displaying the legitimacy of their parental relationships to extended family and institutional audiences. For unmarried heterosexual couples, surnames display ‘intact’ families and paternal commitment whereas for lesbian couples the legitimacy concern is the recognition of the same-sex couple as parents.
Inclusion complexation between baicalein and β-cyclodextrin and the influence of β-cyclodextrin on the binding of baicalein with DNA: A spectroscopic approach
Creators: name: Sameena, Yousuf
name: Sowrirajan Chandrasekaran
name: V.M.V., Enoch Israel
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Molecular Biology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Physics
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: This work deals with the commonly studied cyclic oligosaccharide and gains importance as it is entered on a drug delivering carbohydrate and provides insight into the oligosaccharide complex–biomolecular interaction. The binding of a flavone, baicalein, to β-cyclodextrin and calf thymus DNA is studied. The binding of baicalein to calf thymus DNA in the presence of β-cyclodextrin is analysed by using the UV-Visible absorption and fluorescence spectroscopy. The mode of binding and structure of the baicalein-β-cyclodextrin complex are reported. The role of the structure and the stoichiometry of the inclusion complex of baicalein-β-cyclodextrin on its influence on DNA binding are analysed.
The impact of lifestyle and ethnocentrism on consumers' purchase intentions of fresh fruit in China
Creators: name: Qing, Ping
name: Lobo, Antonio
name: Chongguang, Li
Publisher: name: Swinburne
Year: 2024

description: Purpose: This paper examines how variables related to lifestyle and ethnocentrism influence Chinese consumers’ attitudes and intentions towards the purchase of domestic and imported fresh fruit. Design/methodology/approach: A survey instrument was developed using established scales and focus groups. Data was collected in the city of Wuhan through structured intercept interviews with consumers at major supermarkets and fruit stores. Structural equation modelling was used to analyse the data. Findings: Chinese consumers’ purchase intention of imported fresh fruit is influenced by lifestyle groups, namely Risk takers and Traditionalists. Also consumers’ ethnocentrism tendencies play an important role in shaping their purchase attitudes towards domestic fresh fruit. Research limitations/implications: Although our research investigated both the sensory and non-sensory purchase attributes of fruits, it failed to shed light on the intended use of imported fruits, e.g. for gifts, self consumption, children, aged parents and ill patients. Additionally, future research should be conducted that is more product and country specific. Practical implications: Marketers should ensure that both sensory and non-sensory purchase attributes of fresh fruit are given due importance, as this will snowball into positive purchase intentions, customer satisfaction and overall profitability for firms. Originality/value: Despite its potential importance, relatively little is known about consumers’ buying behaviour of fresh produce in China. Findings of this study would thus be beneficial to practitioners and policy makers to formulate effective strategies designed to market fresh produce in China.
Bridging the macro to mesoscale: Evaluating the fourth-order anisotropic damage tensor parameters from ultrasonic measurements of an isotropic solid under triaxial stress loading
Creators: name: Olsen, Louise
Publisher: name: Swinburne
Year: 2024

description: One of the most challenging problems which arises in continuum damage mechanics is the selection of variables to describe the internal damage. Many theories have been proposed and various types of damage variables ranging from scalar to vector to tensor quantities have been used. In this paper we consider anisotropic damage and the most general form for damage by using a fourth-order tensor for the damage variables. We demonstrate how experimentally measured quantities can be related to the internal tensorial damage variables. We apply this analysis to experiments of an initially isotropic solid becoming transverse isotropic under triaxial or uniaxial stress loading.
Garra elegans
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Garra
Garra elegans

description: 79. Garra elegans (Günther, 1868)
Common name. Mesopotamian garra
Taxonomy. Original description: Tylognathus elegans Günther, 1868: 64 [Mesopotamia?; no types known].
Revisions. None.
Illustrations. Freyhof (2016).
Distribution in Iran. —Distribution in River Basin: Tigris.—Distribution in Ecoregions: 442-Upper Tigris & Euphrates.
Status in Iran. [Native].—Gel cheragh–e ziba.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020) and Eagderi et al. (2022); but needs confirmation by specimens for Iran.—Iran material: None.
Conservation. —IUCN: LC.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 31, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
A review of the molar morphology and phylogenetic affinities of Sillustania quechuense (Metatheria, Polydolopimorphia, Sillustaniidae), from the early Paleogene of Laguna Umayo, southeastern Peru
Creators: name: Chornogubsky, Laura
name: Goin, Francisco J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biophysics
subject: Science Policy
subject: Cancer
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Biotechnology
subject: Biochemistry

description: SUPPLEMENTAL DATASupplemental materials are available for this article for free at www.tandfonline.com/UJVP
High-resolution rovibrational spectroscopy of fluorobenzene, C6H5F: analysis of the B1 fundamentals ν4, ν10b, ν17b, the B2 fundamental ν15 and assignment of the A1 levels ν12, 2ν16a and 2ν18b†
Creators: name: Albert, Sieghard
name: Keppler, Karen
name: Quack, Martin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Cell Biology
subject: Physics
subject: Engineering
subject: Biophysics

description: We report the rovibrational analysis of the highly resolved (instrumental bandwidth = 0.0008–0.0018 cm−1 full width at half maximum [FWHM]) Fourier transform infrared (FTIR) spectrum of fluorobenzene measured with our Zurich Fourier transform interferometric spectrometer prototype (Bruker IFS 125 HR ZP 2001) in the range 600–1300 cm−1. The analysis comprised initially three B1 bands and led to an identification of Coriolis resonances and a new assignment of three A1 bands in the region 790–850 cm−1. In detail, three B1 fundamentals, ν4 ( cm−1), ν10b ( cm−1) and ν17b ( cm−1) have been analysed using an effective Hamiltonian. A perturbation of the B2 fundamental ν15 ( cm−1) was detected and the interaction is interpreted as a crossing Coriolis resonance between the states ν15 and a dark state assigned as ν4 + ν18b. The Coriolis parameter ξx was determined to be −0.00345 cm−1. The rovibrational analysis of the region between 790 and 850 cm−1 revealed three A1 bands assigned to ν12 ( cm−1), 2ν18b ( cm−1) and 2ν16a ( cm−1). A Coriolis resonance between the states 2ν16a and a dark state assigned as ν10a ( cm−1, A2 symmetry) was identified and the Coriolis coupling constant ξz was determined to be 0.0145 cm−1. The root mean square deviation drms is in the range 0.0002 − 0.0003 cm−1 (6–9 MHz) for the adjustment of the model to almost 17000 assigned rovibrational absorption line positions. This indicates an excellent representation of the data by the model.
Absorption spectra and aqueous photochemistry of β-hydroxyalkyl nitrates of atmospheric interest
Creators: name: Romonosky, Dian E.
name: Nguyen, Lucas Q.
name: Shemesh, Dorit
name: Nguyen, Tran B.
name: Epstein, Scott A.
name: Martin, David B.C.
name: Vanderwal, Christopher D.
name: R. Benny Gerber
name: Nizkorodov, Sergey A.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: Molar absorption coefficients were measured for select alkyl nitrates and β-hydroxyalkyl nitrates in methanol. The presence of the β-hydroxyl group has a relatively minor effect on the absorption spectrum in the vicinity of the weak n → π* transition, which is responsible for photolysis of organic nitrates in the atmosphere. For both alkyl nitrates and β-hydroxyalkyl nitrates, there is an enhancement in the absorption coefficients in solution compared to the gas-phase values. The effect of the β-hydroxyl group on the spectra was modelled with molecular dynamics simulations using an OM2/GUGA-CI Hamiltonian for ethyl nitrate and β-hydroxyethyl nitrate. The simulation provided a qualitatively correct shape of the low energy tail of the absorption spectrum, which is important for atmospheric photochemistry. The role of direct aqueous photolysis in removal of β-hydroxyalkyl nitrates in cloud and fog water was modelled using a relative rate approach, and shown to be insignificant relative to gas-phase photochemical processes and aqueous OH oxidation under typical atmospheric conditions.
Sequence variants on 17q21 are associated with the susceptibility of asthma in the population of Lahore, Pakistan
Creators: name: Ziaur Rahman
name: Iqbal, Zafar
name: Iqbal, Muhammad
name: Tayyab Husnain
name: Shahid, Mariam
name: Sabar, Muhammad Farooq
name: Bano, Iqbal
name: Sayyeda Saadia Fatim Ali
name: Ghani, Muhammad Usman
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences

description: Objective: Single nucleotide polymorphisms (SNPs) on 17q21 are known to be associated with asthma disease in multiple populations. This study was designed to know whether this region is associated with asthma in Lahore region population or not. Methods: A total of 200 asthma patients and 100 healthy controls were enrolled from different hospitals of Lahore, Pakistan. Twelve SNPs from chromosomal region 17q21 were analyzed in cases and controls by single base extension method and capillary-based genetic analyzers. Associations with asthma were checked using basic allelic model, genotypic model, and results were adjusted by logistic regression analysis using PLINK v1.9. Pair-wise linkage disequilibrium among the SNPs was analyzed by using Haploview software. Results: SNP rs3816470 showed a strong association (p = 8.89 × 10−5, Odd Ratio = 3.082 [1.755-5.41]) with asthma, whereas rs3859192 and rs6503525 also showed a significant association with the development of asthma, especially in the case of positive family history. In LD block1 (93 kb) consisting of six SNPs (rs12936231, rs7216389, rs7216558, rs9894164, rs1007654 and rs7212938), none of the haplotypes show any significant association with asthma except the haplotype “CCTCAG”, which is a significant protective factor against asthma having frequency 0.051 in controls while 0.017 in cases (p = 3.56 × 10−2, χ2 = 4.415). Conclusion: The present study reports that the polymorphic genomic variant rs3816470 is significantly and independently associated with asthma in the studied population, while the variants, rs6503525 and rs3859192, also indicate a significant association with asthma in this population when family history of the disease is taken as a covariate.
Attitudes towards schizophrenia on YouTube: A content analysis of Finnish and Greek videos
Creators: name: Athanasopoulou, Christina
name: Suni, Sanna
name: Hätönen, Heli
name: Apostolakis, Ioannis
name: Lionis, Christos
name: Välimäki, Maritta
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objective: To investigate attitudes towards schizophrenia and people with schizophrenia presented in YouTube videos. Methods: We searched YouTube using the search terms “schizophrenia” and “psychosis” in Finnish and Greek language on April 3rd, 2013. The first 20 videos from each search (N = 80) were retrieved. Deductive content analysis was first applied for coding and data interpretation and it was followed by descriptive statistical analysis. Results: A total of 52 videos were analyzed (65%). The majority of the videos were in the “Music” category (50%, n = 26). Most of the videos (83%, n = 43) tended to present schizophrenia in a negative way, while less than a fifth (17%, n = 9) presented schizophrenia in a positive or neutral way. Specifically, the most common negative attitude towards schizophrenia was dangerousness (29%, n = 15), while the most often identified positive attitude was objective, medically appropriate beliefs (21%, n = 11). All attitudes identified were similarly present in the Finnish and Greek videos, without any statistically significant difference. Conclusions: Negative presentations of schizophrenia are most likely to be accessed when searching YouTube for schizophrenia in Finnish and Greek language. More research is needed to investigate to what extent, if any, YouTube viewers’ attitudes are affected by the videos they watch.
Safety climate of commercial pilots: The effect of pilot ranks and employment experiences
Creators: name: Gao, Yi
name: Bruce, Peter
name: Newman, David Glen
name: Zhang, Chrystal
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 350901
subject: Air transportation and freight services

description: This study designed and conducted a survey to examine the safety climate of the flight crew of an Asia-Pacific airline. The survey instrument collected responses of flight crew to a list of statements deemed relevant to their safety climate. Exploratory factor analysis identified and confirmed four safety related themes covering 15 survey items, which were named Safety Feedback, Confidence in Safety Reporting System, Company Safety Philosophy, and Safety Promotion & Communication. The survey results showed that a majority of participants responded positively to statements captured by these four themes, indicating a generally healthy safety climate within the airline. Statistical analyses also revealed that pilots of lower ranks and shorter employment experience with the company generally were more positive about the safety climate than senior pilots. Comments provided by flight crew confirmed findings of quantitative analysis, and also identified key areas to improve the overall safety culture of the company.
Molecular Basis of Ubiquitin Recognition by the Autophagy Receptor CALCOCO2
Creators: name: Xingqiao Xie
name: Faxiang Li
name: Yuanyuan Wang
name: Yingli Wang
name: Zhijie Lin
name: Xiaofang Cheng
name: Jianping Liu
name: Changbin Chen
name: Lifeng Pan
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Cancer
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Cell Biology
subject: Engineering
subject: Biochemistry

description: The autophagy receptor CALCOCO2/NDP52 functions as a bridging adaptor and plays an essential role in the selective autophagic degradation of invading pathogens by specifically recognizing ubiquitin-coated intracellular pathogens and subsequently targeting them to the autophagic machinery; thereby it is required for innate immune defense against a range of infectious pathogens in mammals. However, the mechanistic basis underlying CALCOCO2-mediated specific recognition of ubiqutinated pathogens is still unknown. Here, using biochemical and structural analyses, we demonstrated that the cargo-binding region of CALCOCO2 contains a dynamic unconventional zinc finger as well as a C2H2-type zinc-finger, and only the C2H2-type zinc finger specifically recognizes mono-ubiquitin or poly-ubiquitin chains. In addition to elucidating the specific ubiquitin recognition mechanism of CALCOCO2, the structure of the CALCOCO2 C2H2-type zinc finger in complex with mono-ubiquitin also uncovers a unique zinc finger-binding mode for ubiquitin. Our findings provide mechanistic insight into how CALCOCO2 targets ubiquitin-decorated pathogens for autophagic degradations.
The structure of mental health research: networks of influence among psychiatry and clinical psychology journals
Creators: name: Haslam, N.
name: Lusher, Dean
Publisher: name: Swinburne
Year: 2024

description: Background. Psychiatry and clinical psychology are the two dominant disciplines in mental health research, but the structure of scientific influence and information flow within and between them has never been mapped.Method. Citations among 96 of the highest impact psychiatry and clinical psychology journals were examined, based on 10 052 articles published in 2008. Network analysis explored patterns of influence between journal clusters.Results. Psychiatry journals tended to have greater influence than clinical psychology journals, and their influence was asymmetrical: clinical psychology journals cited psychiatry journals at a much higher rate than the reverse. Eight journal clusters were found, most dominated by a single discipline. Their citation network revealed an influential central cluster of 'core psychiatry' journals that had close affinities with a 'psychopharmacology' cluster. A group of 'core clinical psychology' journals was linked to a 'behavior therapy' cluster but both were subordinate to psychiatry journals. Clinical psychology journals were less integrated than psychiatry journals, and 'health psychology/behavioral medicine' and 'neuropsychology' clusters were relatively peripheral to the network.Conclusions. Scientific publication in the mental health field is largely organized along disciplinary lines, and is to some degree hierarchical, with clinical psychology journals tending to be structurally subordinate to psychiatry journals.
Moon Equation of center_al Khwarizmi by Suter (Heinrich) (1914) | Type-B (ID n° 403)
Creators: name: Suter, Heinrich
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021
Subjects: Astronomy
History of astronomy
DISHAS
Astronomical table

description: This is a type B edition: A type-B edition corresponds to a critical edition of several table witnesses:
 it is based on several different editions, themselves based on tables from different primary sources.
 A type-B edition can be based on type-A, type-B or type-C editions.
You can find it on the DISHAS project website from this link: https://dishas.obspm.fr/table-edition/403
description: Source: Die Astronomischen Taflen des Muhanned Ibn Musa al-Khwarizmi, Suter (Heinrich), 1914
High-resolution rovibrational spectroscopy of fluorobenzene, C6H5F: analysis of the B1 fundamentals ν4, ν10b, ν17b, the B2 fundamental ν
Creators: name: Albert, Sieghard
name: Keppler, Karen
name: Quack, Martin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Biological Sciences
subject: Chemistry
subject: Biotechnology
subject: Cell Biology
subject: Physics
subject: Engineering
subject: Biophysics

description: We report the rovibrational analysis of the highly resolved (instrumental bandwidth = 0.0008–0.0018 cm−1 full width at half maximum [FWHM]) Fourier transform infrared (FTIR) spectrum of fluorobenzene measured with our Zurich Fourier transform interferometric spectrometer prototype (Bruker IFS 125 HR ZP 2001) in the range 600–1300 cm−1. The analysis comprised initially three B1 bands and led to an identification of Coriolis resonances and a new assignment of three A1 bands in the region 790–850 cm−1. In detail, three B1 fundamentals, ν4 ( cm−1), ν10b ( cm−1) and ν17b ( cm−1) have been analysed using an effective Hamiltonian. A perturbation of the B2 fundamental ν15 ( cm−1) was detected and the interaction is interpreted as a crossing Coriolis resonance between the states ν15 and a dark state assigned as ν4 + ν18b. The Coriolis parameter ξx was determined to be −0.00345 cm−1. The rovibrational analysis of the region between 790 and 850 cm−1 revealed three A1 bands assigned to ν12 ( cm−1), 2ν18b ( cm−1) and 2ν16a ( cm−1). A Coriolis resonance between the states 2ν16a and a dark state assigned as ν10a ( cm−1, A2 symmetry) was identified and the Coriolis coupling constant ξz was determined to be 0.0145 cm−1. The root mean square deviation drms is in the range 0.0002 − 0.0003 cm−1 (6–9 MHz) for the adjustment of the model to almost 17000 assigned rovibrational absorption line positions. This indicates an excellent representation of the data by the model.
Garra hormuzensis Zamani-Faradonbe, Zhang & Keivany 2021
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Garra
Garra hormuzensis

description: 81. Garra hormuzensis Zamani-Faradonbe, Zhang & Keivany, 2021
Common name. Hormuz garra
Taxonomy. Original description: Garra hormuzensis Zamani-Faradonbe, Zhang & Keivany, 2021: 385, figs. 2-6 [Shur River about 12 km west of Hajiabad, upper Kol River basin, Hormuzgan Province, Iran, 28.1885N, 55.7777E; holotype: IUT-IM GH1].
Revisions. None.
Illustrations. Zamani-Faradonbe et al. (2021: 51, fig. 2), Sayyadzadeh & Esmaeili (2021: 271-273, figs 2-6).
Distribution in Iran. —Distribution in River Basin: Hormuz.—Distribution in Ecoregions: 451-Northern Hormuz Drainages.
Status in Iran. [Endemic].—Gel cheragh-e Hormuz.—Listed in previous checklist from Iran by Eagderi et al. (2022).—Iran material: ZM-CBSU.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on pages 31-32, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Garra lorestanensis Mousavi-Sabet & Eagderi 2016
Creators: name: Sayyadzadeh, Golnaz
name: Esmaeili, Hamid Reza
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Chordata
Cypriniformes
Cyprinidae
Garra
Garra lorestanensis

description: 82. Garra lorestanensis Mousavi-Sabet & Eagderi, 2016
Common name. Blind cave garra
Taxonomy. Original description: Garra lorestanensis Mousavi-Sabet & Eagderi, 2016: 46, figs. 1-4, 8a, 9a, 9b [Loven Cave, Tigris River drainage, Persian Gulf basin, Lorestan Province, Iran, 33°04'39"N, 48°35'33"E; holotype: VMFC GL-H].— Iran Middle Eastern synonyms: None.—Revisions: None.—Illustration: Mousavi-Sabet & Eagderi (2016: 46, fig. 1).
Revisions. None.
Illustrations. Esmaeili et al. (2016a: 100, fig. 15).
Distribution in Iran. —Distribution in River Basin: Tigris.—Distribution in Ecoregions: 442-Upper Tigris & Euphrates.
Status in Iran. [Endemic].—Mahi koor-e lorestani.—Listed in previous checklists from Iran by Esmaeili et al. (2017 a, 2018); Jouladeh-Roudbar et al. (2020) and Eagderi et al. (2022).—Iran material: VMFC.
Conservation. —IUCN: NE.
description: Published as part of Sayyadzadeh, Golnaz & Esmaeili, Hamid Reza, 2024, Freshwater lamprey and fishes of Iran: Reappraisal and updated checklist with a note on Eagderi et al. (2022), pp. 1-99 in Zootaxa 5402 (1) on page 32, DOI: 10.11646/zootaxa.5402.1.1, http://zenodo.org/record/10524097
Psychotherapy and pharmacotherapy interventions to reduce distress or improve well-being in people with amyotrophic lateral sclerosis: A systematic review
Creators: name: Gould, Rebecca L.
name: Coulson, Mark C.
name: Brown, Richard G.
name: Goldstein, Laura H.
name: Al-Chalabi, Ammar
name: Howard, Robert J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Science Policy
Biological Sciences
Medicine

description: Our objective was to systematically review and critically evaluate the evidence for psychotherapy and pharmacotherapy interventions for reducing distress or improving well-being in people with amyotrophic lateral sclerosis (pwALS). Online bibliographic databases and clinical trial registers were searched and an assessment of study quality was conducted. Seven thousand two hundred and twenty-three studies were identified, of which five met inclusion criteria (four completed and one in progress). All studies examined psychotherapeutic interventions, and no studies investigated pharmacotherapy. Two studies adopted a randomized controlled trial design, one a controlled trial design and two a cohort design. Sample sizes were small in all studies (overall n = 145). The quality of completed studies was generally poor, with evidence that all were at potential risk of bias in numerous areas. Improvements in well-being were found with expressive disclosure (compared to no disclosure), cognitive behavioural therapy/counselling (compared to non-randomized pharmacotherapy) and hypnosis in the short term only, while no improvements were seen with a life review intervention. In conclusion, there is currently insufficient evidence to recommend the use of specific psychotherapy interventions for reducing distress or improving well-being in pwALS, and no evidence to support pharmacotherapy interventions. Research is urgently needed to address these significant gaps in the literature.
Research on the design of an optical information storage sensing system using a diffractive optical element
Creators: name: Cheng, Xuemin
name: Hao, Qun
name: Hou, Jianbo
name: Li, Xiangping
name: Ma, Jianshe
name: Gu, Min
Publisher: name: Swinburne
Year: 2024

description: This paper introduces a compact optical information storage sensing system. Applications of this system include longitudinal surface plasmon resonance detection of gold nanorods with a single femtosecond laser in three-dimensional space as well as data storage. A diffractive optical element (DOE) is applied in the system to separate the recording-reading beam from the servo beam. This allows us to apply a single laser and one objective lens in a single optical path for the servo beam and the recording-reading beam. The optical system has a linear region of 8 λ, which is compatible with current DVD servo modules. The wavefront error of the optical system is below 0.03 λrms. The minimum grating period of the DOE is 13.4 μm, and the depth of the DOE is 1.2 μm, which makes fabrication of it possible. The DOE is also designed to conveniently control the layer-selection process, as there is a linear correlation between the displacement of the DOE and the layer-selection distance. The displacement of DOE is in the range of 0-6.045 mm when the thickness of the layer-selection is 0.3 mm. Experiments were performed and the results have been verified.
Ni(II) and Cu(II) complexes of new unsymmetrical N2O2 Schiff bases derived from 3-(2-aminobenzylimino)-1-phenylbutan-1-ol: synthesis, structure, antibacterial properties, and electrochemistry
Creators: name: Soraia Meghdadi
name: Amirnasr, Mehdi
name: Mereiter, Kurt
name: Somayeh Motaharipour
name: Monireh Nasehi
name: Bagheri, Maryam
name: Abbasi, Soheila
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Cell Biology
Biochemistry
Biophysics

description: Two new N2O2 unsymmetrical Schiff bases, H2L1 = 3-[({o-[(E)-(o-hydroxyphenyl)methylideneamino]phenyl}methyl)imino]-1-phenyl-1-buten-1-ol and H2L2 = 3-[({o-[(E)-(2-hydroxy-1-naphthyl)methylideneamino]phenyl}methyl)imino]-1-phenyl-1-buten-1-ol, and their copper(II) and nickel(II) complexes, [CuL1] (1), [CuL2] (2), [NiL1] (3), and [NiL2] (4), have been synthesized and characterized by elemental analyses and spectroscopic methods. The crystal structures of these complexes have been determined by X-ray diffraction. The coordination geometry around Cu(II) and Ni(II) centers is described as distorted square planar in all complexes with the CuN2O2 coordination more distorted than the Ni ones. The electrochemical studies of these complexes indicate a good correlation between the structural distortion and the redox potentials of the metal centers. The ligand and metal complexes were also screened for their in vitro antibacterial activity.
Attitudes towards schizophrenia on YouTube: a content analysis of Finnish and Greek videos
Creators: name: Lionis, Christos
name: Athanasopoulou, Christina
name: Suni, Sanna
name: Hätönen, Heli
name: Apostolakis, Ioannis
name: Välimäki, Maritta
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Earth and Environmental Sciences
subject: Cell Biology

description: Objective: To investigate attitudes towards schizophrenia and people with schizophrenia presented in YouTube videos.Methods: We searched YouTube using the search terms “schizophrenia” and “psychosis” in Finnish and Greek language on April 3rd, 2013. The first 20 videos from each search (N = 80) were retrieved. Deductive content analysis was first applied for coding and data interpretation and it was followed by descriptive statistical analysis.Results: A total of 52 videos were analyzed (65%). The majority of the videos were in the “Music” category (50%, n = 26). Most of the videos (83%, n = 43) tended to present schizophrenia in a negative way, while less than a fifth (17%, n = 9) presented schizophrenia in a positive or neutral way. Specifically, the most common negative attitude towards schizophrenia was dangerousness (29%, n = 15), while the most often identified positive attitude was objective, medically appropriate beliefs (21%, n = 11). All attitudes identified were similarly present in the Finnish and Greek videos, without any statistically significant difference.Conclusions: Negative presentations of schizophrenia are most likely to be accessed when searching YouTube for schizophrenia in Finnish and Greek language. More research is needed to investigate to what extent, if any, YouTube viewers’ attitudes are affected by the videos they watch.