Additional file 1 of Synthesis, molecular docking, and cytotoxicity of quinazolinone and dihydroquinazolinone derivatives as cytotoxic agents
Creators: name: Taayoshi, Fahimeh
name: Iraji, Aida
name: Moazzam, Ali
name: Soleimani, Meysam
name: Asadi, Mehdi
name: Pedrood, Keyvan
name: Akbari, Mosayeb
name: Salehabadi, Hafezeh
name: Larijani, Bagher
name: Adibpour, Neda
name: Mahdavi, Mohammad
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Cancer

description: Additional file 1: Figure S1. 1H-NMR of 2-[(2-Methylphenyl)amino]-3-phenylquinazolin-4(3H)-one (5a). Figure S2. Mass data of 2-[(2-Methylphenyl)amino]-3-phenylquinazolin-4(3H)-one (5a). Figure S3. 1H-NMR of 3-(chloromethyl)-2-(phenylamino)quinazolin-4(3H)-one (5b). Figure S4. Mass data of 3-(chloromethyl)-2-(phenylamino)quinazolin-4(3H)-one (5b). Figure S5. 1H-NMR of 3-cyclopropyl-2-(phenylamino)quinazolin-4(3H)-one (5c). Figure S6. Mass data of 3-cyclopropyl-2-(phenylamino)quinazolin-4(3H)-one (5c). Figure S7. 1H-NMR of 3-(4-methoxyphenyl)-2-(phenylamino)quinazolin-4(3H)-one (5d). Figure S8. Mass data of 3-(4-methoxyphenyl)-2-(phenylamino)quinazolin-4(3H)-one (5d). Figure S9. 1H-NMR of 3-isopropyl-2-(phenylamino)quinazolin-4(3H)-one (5e). Figure S10. Mass data of 3-isopropyl-2-(phenylamino)quinazolin-4(3H)-one (5e). Figure S11. 1H-NMR of 3-benzyl-2-(4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10a). Figure S12. Mass data of 3-benzyl-2-(4-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10a). Figure S13. 1H-NMR of 3-benzyl-2-(4-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3 dihydroquinazolin-4(1H)-one (10b). Figure S14. Mass data of 3-benzyl-2-(4-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3 dihydroquinazolin-4(1H)-one (10b). Figure S15. 1H-NMR of 3-benzyl-2-(4-((1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10c). Figure S16. Mass data of 3-benzyl-2-(4-((1-(4-chlorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10c). Figure S17. 1H-NMR of 3-benzyl-2-(4-((1-(4-bromobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10d). Figure S18. Mass data of 3-benzyl-2-(4-((1-(4-bromobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10d). Figure S19. 1H-NMR of 3-(4-fluorobenzyl)-2-(4-((1-(2-methylbenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10e). Figure S20. Mass of 3-(4-fluorobenzyl)-2-(4-((1-(2-methylbenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10e). Figure S21. 1H-NMR of 3-(4-fluorobenzyl)-2-(4-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10f). Figure S21. Mass of 3-(4-fluorobenzyl)-2-(4-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (10f).