cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Monitoring SARS-CoV-2 RNA in wastewater from a shared septic system and sub-sewershed sites to expand COVID-19 disease surveillance
Creators: name: Kays, Judith
name: Reckling, Stacie
name: Harris, Angela
name: Guidry, Virginia
name: Bailey, Erika
name: Pasha, A. B. Tanvir
name: Berkowitz, Steven
name: Christensen, Ariel
name: de los Reyes, Francis
name: Engel, Lawrence S.
name: Holcomb, David
name: Kotlarz, Nadine
Publisher: name: IWA Publishing
Year: 2024

description: Wastewater-based epidemiology has expanded as a tool for collecting COVID-19 surveillance data, but there is limited information on the feasibility of this form of surveillance within decentralized wastewater systems (e.g., septic systems). This study assessed SARS-CoV-2 RNA concentrations in wastewater samples from a septic system servicing a mobile home park (66 households) and from two pumping stations serving a similarly sized (71 households) and a larger (1,000 households) neighborhood within a nearby sewershed over 35 weeks in 2020. Also, raw wastewater from a hospital in the same sewershed was sampled. The mobile home park samples had the highest detection frequency (39/39 days) and mean concentration of SARS-CoV-2 RNA (2.7 × 10 7 gene copies/person/day for the N1) among the four sampling sites. N1 gene and N2 gene copies were highly correlated across mobile home park samples (Pearson's r = 0.93, p < 0.0001). In the larger neighborhood, new COVID-19 cases were reported every week during the sampling period; however, we detected SARS-CoV-2 RNA in 12% of the corresponding wastewater samples. The results of this study suggest that sampling from decentralized wastewater infrastructure can be used for continuous monitoring of SARS-CoV-2 infections.
A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2
Creators: name: Palei, Shubhendu
name: Weisner, Jörn
name: Vogt, Melina
name: Gontla, Rajesh
name: Buchmuller, Benjamin
name: Ehrt, Christiane
name: Grabe, Tobias
name: Kleinbölting, Silke
name: Müller, Matthias
name: Clever, Guido H.
name: Rauh, Daniel
name: Summerer, Daniel
Publisher: name: TU Dortmund
Year: 2022
Subjects: subject: 570
subject: 540
subject: Epigenetik
subject: Genregulation
subject: Säugetiere
subject: DNS
subject: Fluoreszenz-Resonanz-Energie-Transfer
subject: Struktur-Aktivitäts-Beziehung

description: Ten-eleven translocation dioxygenases (TETs) are the erasers of 5-methylcytosine (mC), the central epigenetic regulator of mammalian DNA. TETs convert mC to three oxidized derivatives with unique physicochemical properties and inherent regulatory potential, and it initializes active demethylation by the base excision repair pathway. Potent small molecule inhibitors would be useful tools to study TET functions by conditional control. To facilitate the discovery of such tools, we here report a high-throughput screening pipeline and its application to screen and validate 31.5k compounds for inhibition of TET2. Using a homogenous fluorescence assay, we discover a novel quinoline-based scaffold that we further validate with an orthogonal semi-high throughput MALDI-MS assay for direct monitoring of substrate turnover. Structure–activity relationship (SAR) studies involving >20 derivatives of this scaffold led to the identification of optimized inhibitors, and together with computational studies suggested a plausible model for its mode of action.
description: RSC medicinal chemistry;13(12)
MS Gr. class. c. 6 1258
Creators: name: Oxyrhynchus Papyri
Publisher: name: University of Oxford
Year: 2023
Subjects: classificationCode: 470316
subject: Latin and classical Greek languages

description: P.Herc. 1479 fr. 8 col. 3. Epicurus, De natura 28
Drawing by Carlo Orazi
Simulating the Large-Scale Structure of HI Intensity Maps
Creators: name: Seehars, Sebastian
name: Paranjape, Aseem
name: Witzemann, Amadeus
name: Refregier, Alexandre
name: Amara, Adam
name: Akeret, Joel
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Intensity mapping of neutral hydrogen (HI) is a promising observational probe of cosmology and large-scale structure. We present wide field simulations of HI intensity maps based on N-body simulations of a $2.6\, {\rm Gpc / h}$ box with $2048^3$ particles (particle mass $1.6 \times 10^{11}\, {\rm M_\odot / h}$). Using a conditional mass function to populate the simulated dark matter density field with halos below the mass resolution of the simulation ($10^{8}\, {\rm M_\odot / h} < M_{\rm halo} < 10^{13}\, {\rm M_\odot / h}$), we assign HI to those halos according to a phenomenological halo to HI mass relation. The simulations span a redshift range of 0.35 < z < 0.9 in redshift bins of width $Δz \approx 0.05$ and cover a quarter of the sky at an angular resolution of about 7'. We use the simulated intensity maps to study the impact of non-linear effects and redshift space distortions on the angular clustering of HI. Focusing on the autocorrelations of the maps, we apply and compare several estimators for the angular power spectrum and its covariance. We verify that these estimators agree with analytic predictions on large scales and study the validity of approximations based on Gaussian random fields, particularly in the context of the covariance. We discuss how our results and the simulated maps can be useful for planning and interpreting future HI intensity mapping surveys.
description: 35 pages, 19 Figures. Accepted for publication in JCAP
Barriers to PrEP Uptake in Durham County, NC
Creators: name: Zeagler, Mason
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2019

description: Introduction: Pre-Exposure Prophylaxis (PrEP) is a once-daily medication introduced in 2012 that is utilized in the realm of public health as an effective method HIV prevention. However, PrEP uptake has proven to be limited among high-risk populations, and the barriers to these persons face to uptake are just beginning to be researched. This study sought to understand the barriers that impede patients at risk of HIV that visited the Adult Sexual Health Clinic (AHC) of the Durham County Department of Public Health (DCoDPH) in North Carolina.   Methods: This cross-sectional study utilized a structured, quantitative questionnaire to gather data from a sample of patients of the AHC that were identified as being at high-risk of HIV and did not meet their initial PrEP referral appointment. The questionnaire was constructed through a detailed review of the prior literature that exists on barriers to PrEP uptake, and the questionnaire was administered over the phone at the AHC via DCoDPH personnel in the April 2019   Results: 10 of the 28 patients included within the study sample responded to reasons why they missed their first appointment, and 8 completed the entire questionnaire. Due to the number of respondents, the data collected had little statistical significance, but it produced important information about the perceptions of barriers to PrEP uptake among the AHC patients. Half (four) of the questionnaire respondents did not relate to any of the barriers to PrEP uptake that were identified from the existing literature, and the majority of respondents (six) reported patient-centered barriers to their first appointment PrEP appointment.   Conclusions: There are barriers to PrEP uptake that are salient to the AHC patients and exist beyond the purview of prior literature. This study serves as a pilot study to an evolving investigation of barriers for persons at high risk of HIV living in Durham County. It demonstrates that as PrEP research develops, researchers will need to continue to evaluate and redefine what barriers exist for individuals within high-risk populations.
Durability of Protection Against COVID-19 Through the Delta Surge for the NVX-CoV2373 Vaccine
Creators: name: Fay, Michael P
name: Woo, Wayne
name: Fong, Youyi
name: Nason, Martha
name: Mateja, Allyson
name: Huang, Yunda
name: Kotloff, Karen
name: Magaret, Craig A
name: Gay, Cynthia L
name: Dunkle, Lisa M
name: Cho, Iksung
name: Angier, Heather
name: Follmann, Dean
Publisher: name: Oxford University Press (OUP)
Year: 2024

description: BACKGROUND: Protein-based vaccines for coronavirus disease 2019 (COVID-19) provide a traditional vaccine platform with long-lasting protection for non-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogens and may complement messenger RNA vaccines as a booster dose. While NVX-CoV2373 showed substantial early efficacy, the durability of protection has not been delineated.
METHODS: The PREVENT-19 vaccine trial used a blinded crossover design; the original placebo arm received NVX-CoV2373 after efficacy was established. Using novel statistical methods that integrate surveillance data of circulating strains with post-crossover cases, we estimated placebo-controlled vaccine efficacy and durability of NVX-CoV2373 against both pre-Delta and Delta strains of SARS-CoV-2.
RESULTS: Vaccine efficacy against pre-Delta strains of COVID-19 was 89% (95% CI, 75-95%) and 87% (72-94%) at 0 and 90 days after 2 doses of NVX-CoV2373, respectively, with no evidence of waning (P = .93). Vaccine efficacy against the Delta strain was 88% (71-95%), 82% (56-92%), and 77% (44-90%) at 40, 120, and 180 days, respectively, with evidence of waning (P < .01). In sensitivity analyses, the estimated Delta vaccine efficacy at 120 days ranged from 66% (15-86%) to 89% (74-95%) per various assumptions of the surveillance data.
CONCLUSIONS: NVX-CoV2373 has high initial efficacy against pre-Delta and Delta strains of COVID-19 with little evidence of waning for pre-Delta strains through 90 days and moderate waning against Delta strains over 180 days.
MS Gr. class. c. 6 1259
Creators: name: Oxyrhynchus Papyri
Publisher: name: University of Oxford
Year: 2023
Subjects: classificationCode: 470316
subject: Latin and classical Greek languages

description: P.Herc. 1479 fr. 5 col. 4. Epicurus, De natura 28
Drawing by Carlo Orazi
Open geospatial data publication at ITC
Creators: name: Shariat, Masoome
Publisher: name: Zenodo
Year: 2023
Subjects: open data
research data management
geospatial data
earth observation
flagship dataset

description: ITC as a publisher of open geospatial data. Many researchers at ITC generate, process, and analyse high-quality geospatial data with potential for further impact. Hence, ITC could become a known provider of such important data sets. However, research data is often seen as a secondary side product and dumped on repositories (e.g., DANS) disregarding its opportunities for practical application and reuse by others. Moreover, general purpose repositories are not explicitly designed for geospatial data sources and thus lacks many opportunities spatial information can provide. A lighthouse geospatial data publication is a way of presenting data in a fully transparent way that optimises application, reuse, and decision-making. Users can explore ready-to-use geospatial data and its spatiotemporal properties interactively via the browser without installing any tools on their local computers. An essential requirement of this endeavour is to publish fully documented and open geospatial data with the help of a README, and the reproducible analysis workflows providing the context of the data in a computational environment. The first phase of this project was to conduct a “data scan” across all ITC departments to identify potential flagship datasets as candidates for a few publications showcases. A set of criteria were defined to identify these flagship datasets. The second phase was to develop a data publication model that optimizes the re-use of the data. The third phase, which is currently in progress, is to implement the proposed data publication model on a few flagship datasets and develop support guidelines and templates for scientists and students at ITC to publish their data. This initiative facilitates open geospatial data publication procedure, supports researchers to develop their skills to publish and re-use scientific data, promotes scientific data publications as a recognised first-class research output, and fosters more cooperation within and beyond ITC by providing open and re-usable data.
Fragmentation contributions to hadroproduction of prompt $J/ψ$, $χ_{cJ}$, and $ψ(2S)$ states
Creators: name: Bodwin, Geoffrey T.
name: Chao, Kuang-Ta
name: Chung, Hee Sok
name: Kim, U-Rae
name: Lee, Jungil
name: Ma, Yan-Qing
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We compute fragmentation corrections to hadroproduction of the quarkonium states $J/ψ$, $χ_{cJ}$, and $ψ(2S)$ at leading power in $m_c^2/p_T^2$, where $m_c$ is the charm-quark mass and $p_T$ is the quarkonium transverse momentum. The computation is carried out in the framework of nonrelativistic QCD. We include corrections to the parton-production cross sections through next-to-leading order in the strong coupling $α_s$ and corrections to the fragmentation functions through second order in $α_s$. We also sum leading logarithms of $p_T^2/m_c^2$ to all orders in perturbation theory. We find that, when we combine these leading-power fragmentation corrections with fixed-order calculations through next-to-leading order in $α_s$, we are able to obtain good fits for $p_T\geq 10$ GeV to hadroproduction cross sections that were measured at the Tevatron and the LHC. Using values for the nonperturbative long-distance matrix elements that we extract from the cross-section fits, we make predictions for the polarizations of the quarkonium states. We obtain good agreement with measurements of the polarizations, with the exception of the CDF Run II measurement of the prompt $J/ψ$ polarization, for which the agreement is only fair. In the predictions for the prompt-$J/ψ$ cross sections and polarizations, we take into account feeddown from the $χ_{cJ}$ and $ψ(2S)$ states.
description: 41 pages, 21 figures, minor revisions, Figure 20 corrected, version published in Phys. Rev. D
Experimental study of internal wave generation by convection in water
Creators: name: Bars, Michael Le
name: Lecoanet, Daniel
name: Perrard, Stéphane
name: Ribeiro, Adolfo
name: Rodet, Laetitia
name: Aurnou, Jonathan M.
name: Gal, Patrice Le
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We experimentally investigate the dynamics of water cooled from below at 0^oC and heated from above. Taking advantage of the unusual property that water's density maximum is at about 4^oC, this set-up allows us to simulate in the laboratory a turbulent convective layer adjacent to a stably stratified layer, which is representative of atmospheric and stellar conditions. High precision temperature and velocity measurements are described, with a special focus on the convectively excited internal waves propagating in the stratified zone. Most of the convective energy is at low frequency, and corresponding waves are localized to the vicinity of the interface. However, we show that some energy radiates far from the interface, carried by shorter horizontal wavelength, higher frequency waves. Our data suggest that the internal wave field is passively excited by the convective fluctuations, and the wave propagation is correctly described by the dissipative linear wave theory.
Geochemistry of bottom sediments -- Matagorda Bay system, Texas
Creators: name: McGowen, J. H.
name: Wilkinson, Bruce H., 1942-
name: Byrne, J. R.
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1979
Subjects: Geochemistry -- Texas -- Matagorda Bay
Marine sediments -- Texas -- Matagorda Bay

description: Bureau Publication GC7902 - to purchase a print copy please go to: https://store.beg.utexas.edu/geologic-circulars/442-gc7902.html
description: Approximately 800 sediment samples from stream beds and bay bottoms of water bodies that compose the Matagorda Bay system were collected and analyzed. Shell-sand-mud ratios and total organic carbon content were determined, and 20 trace elements were detected. In general, highest concentrations of trace elements coincide with deep areas of- water bodies, areas of mud accumulation, and areas with high total organic carbon content. Zirconium, calcium, strontium, and mercury do not follow the distribution patterns of most other elements. Zirconium (Zr) is concentrated in sand located chiefly along bay margins and in tidal deltas; high Zr values result from the physical concentration of zircons as heavy mineral placers associated with sand bodies. Calcium and strontium distributions coincide with distribution of shell material. Mercury distribution is restricted to Lavaca Bay and northwestern Matagorda Bay. When concentrations of 20 trace metals in the Matagorda Bay system are compared with concentrations of elements in the crust, shale or clay, and seawater, it is found that (1) Matagorda Bay sediment contains trace elements in about the same concentrations as crustal rocks and shale but exhibits concentrations higher than seawater, and (2) only two elements, boron and mercury, identified within bay-system sediment exhibited anomalously high concentrations. These high concentrations are believed to result from man's activities within the Texas Coastal Zone.
MS Gr. class. c. 6 1260
Creators: name: Oxyrhynchus Papyri
Publisher: name: University of Oxford
Year: 2023
Subjects: classificationCode: 470316
subject: Latin and classical Greek languages

description: P.Herc. 1479 fr. 13 col. 3 sup. Epicurus, De natura 28
Drawing by Carlo Orazi
Translation in action: Influence, collaboration, and evolution of COVID‐19 research with Clinical and Translational Science Awards consortium support
Creators: name: Casey, Shannon
name: Hoyo, Verónica
name: Pelfrey, Clara
name: Flynn, David
name: Dave, Gaurav
name: Fournier, Deborah
name: DiazGranados, Deborah
name: Nehl, Eric J.
name: Llewellyn, Nicole
Publisher: name: Wiley
Year: 2024

description: The National Institutes of Health (NIH)'s Clinical and Translational Science Awards (CTSA) consortium aims to accelerate translational processes that move discoveries from bench to bedside. The coronavirus disease 2019 (COVID-19) pandemic presented unmatched challenges and applications for CTSA hubs nationwide. Our study used bibliometrics to assess features of COVID-19 publications supported by the national CTSA program to characterize the consortium's response to the pandemic. Our goal was to understand relative scientific influence, collaboration across hubs, and trends in research emphasis over time. We identified publications from NIH's curated iSearch COVID-19 Publication Portfolio from February 2020 to February 2023; 3234 peer-reviewed articles relevant to COVID-19 cited a CTSA grant. All 66 CTSA hubs were represented, with large-size and longstanding hubs contributing more publications. Most publications cited UL1 grants, 457 cited KL2/TL1 training grants, and 164 cited multiple hub grants. Compared to a random sample of non-CTSA-supported COVID-19 publications, the CTSA portfolio exhibited greater clinical relevance, more human research, and higher altmetric and citation influence. Results were similar for multi-hub publications involving networked initiatives like multi-site clinical trials or the National COVID-19 Cohort Collaborative. Shifts from molecular/cellular-oriented research toward human-oriented research over time were evident, demonstrating translation in action. Results illuminate how the CTSA consortium confronted the pandemic through high-quality projects oriented toward human research, working across hubs on high-value collaborations, advancing along the translational spectrum over time. Findings validate CTSA hubs as critical support structures during health emergencies.
Eviction Diversion: A Community-Based Approach to Addressing  High Rates of Eviction in Durham County, North Carolina
Creators: name: Foster, Riley
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2018

description: With one eviction filing per 37.93 residents in 2017, Durham County had the highest per capita eviction rate of any metropolitan county in North Carolina. Landlords filed over 9,000 evictions, which resulted in 5,066 Durham renter households receiving eviction judgments on their housing records. Landlords cite eviction judgments as immediate grounds for disqualification for tenancy, so tenants with judgments on their records have significant difficulty securing new housing. In recent years, eviction has become a primary focus of the affordable housing discussion, but few programs have been implemented to mitigate the direct, negative impact of court ordered eviction judgments, namely homelessness. This Honors Senior Thesis examines the potential for a newly implemented Eviction Diversion Program (ED Program) in Durham County to streamline community resources to better serve the financial and legal needs of low-income renter households in an effort to prevent homelessness. This analysis synthesizes data from court records with information gathered from interviews with ED Program stakeholders in Durham and in five district courts in Michigan that have piloted ED Programs. It is concluded that ED Programs can both increase efficiency in landlord-tenant court proceedings and unite private and public entities committed to reducing homelessness. In Durham, the ED Program has the capacity to assist a small percentage of evicted households in avoiding homelessness. However, stakeholders and community leaders should continue to prioritize the preservation and construction of affordable housing, which more directly addresses the needs of low-income residents in the county.
Importance of secondary leached porosity in lower Tertiary sandstone reservoirs along the Texas Gulf Coast
Creators: name: Loucks, R. G.
name: Galloway, William E.
name: Dodge, M. M.
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1980
Subjects: Porosity
Sandstone -- Texas -- Gulf Region

description: Bureau Publication GC8002 - to purchase a print copy please go to: https://store.beg.utexas.edu/geologic-circulars/446-gc8002.html Tx Doc no.: Z, UA220.7, G292, 80-2 Reprinted from Transactions of the Gulf Coast Association of Geological Societies, vol. 29, 1979.
description: Secondary leached porosity is common to dominant in near surface to deep subsurface lower Tertiary sandstone reservoirs along the Texas Gulf Coast. This secondary porosity is in the form of leached feldspar grains, volcanic rock fragments, carbonate cements, and carbonate-replaced grains. Leached porosity occurs in sandstones with compositions ranging from volcanic litharenite and lithic arkose to quartzose sublitharenite and quartzose subarkose. A generalized diagenetic sequence indicates that leaching is a multi-staged phenomenon occurring at or near surface, at burial depths of 4000 to 6000 ft, and at burial depths of 7000 to 10,000 ft. Feldspar grains are dissolved during the first stage, whereas grains, cements, and replacement products are dissolved during the last two stages. Intensity of leaching in each stage varies in different formations and in different areas. Plots of secondary porosity as a percent of total porosity versus burial depth show that secondary porosity is dominant beneath 10,000 ft, ranging from 50 to 100 percent of total porosity. Above 10,000 ft more than half the samples have secondary porosity as the dominant type. Similarly, individual plots for the Wilcox, Yegua, Vicksburg, and Frio sandstones all demonstrate the predominance of secondary leached porosity. Primary porosity is destroyed by compaction and cementation with increasing depth of burial. If this were the only porosity type, no deep, high-quality reservoirs would exist. Leaching, however, restores reservoir quality after primary porosity has been reduced. Most productive lower Tertiary sandstone reservoirs, especially deep reservoirs, along the Texas Gulf Coast exist only because of secondary leached porosity.
Atomically thin spherical shell-shaped superscatterers based on Bohr model
Creators: name: Li, Rujiang
name: Lin, Xiao
name: Lin, Shisheng
name: Liu, Xu
name: Chen, Hongsheng
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Graphene monolayers can be used for atomically thin three-dimensional shell-shaped superscatterer designs. Due to the excitation of the first-order resonance of transverse magnetic (TM) graphene plasmons, the scattering cross section of the bare subwavelength dielectric particle is enhanced significantly by five orders of magnitude. The superscattering phenomenon can be intuitively understood and interpreted with Bohr model. Besides, based on the analysis of Bohr model, it is shown that contrary to the TM case, superscattering is hard to occur by exciting the resonance of transverse electric (TE) graphene plasmons due to their poor field confinements.
description: This paper has been accepted for publication in Nanotechnology
Computer simulations of single particles in external electric fields
Creators: name: Zhou, Jiajia
name: Schmid, Friederike
Publisher: name: arXiv
Year: 2015
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Applying electric fields is an attractive way to control and manipulate single particles or molecules, e.g., in lab-on-a-chip devices. However, the response of nanosize objects in electrolyte solution to external fields is far from trivial. It is the result of a variety of dynamical processes taking place in the ion cloud surrounding charged particles and in the bulk electrolyte, and it is governed by an intricate interplay of electrostatic and hydrodynamic interactions. Already systems composed of one single particle in electrolyte solution exhibit a complex dynamical behaviour. In this review, we discuss recent coarse-grained simulations that have been performed to obtain a molecular-level understanding of the dynamic and dielectric response of single particles and single macromolecules to external electric fields. We address both the response of charged particles to constant fields (DC fields), which can be characterized by an electrophoretic mobility, and the dielectric response of both uncharged and charged particles to alternating fields (AC fields), which is described by a complex polarizability. Furthermore, we give a brief survey of simulation algorithms and highlight some recent developments.
description: short review, submitted to Soft Matter
Virtual quality improvement collaborative with primary care practices during COVID-19: a case study within a clinically integrated network
Creators: name: Stover, Angela M
name: Morrison, Abigail
name: Booth, Ronni
name: Reed, Christine
name: Caton, Lauren
name: Young, Alexa
name: Shea, Christopher M
name: Rohweder, Catherine L
name: Mottus, Kathleen
Publisher: name: BMJ
Year: 2024

description: INTRODUCTION: Quality improvement collaboratives (QICs) are a common approach to facilitate practice change and improve care delivery. Attention to QIC implementation processes and outcomes can inform best practices for designing and delivering collaborative content. In partnership with a clinically integrated network, we evaluated implementation outcomes for a virtual QIC with independent primary care practices delivered during COVID-19.
METHODS: We conducted a longitudinal case study evaluation of a virtual QIC in which practices participated in bimonthly online meetings and monthly tailored QI coaching sessions from July 2020 to June 2021. Implementation outcomes included: (1) level of engagement (meeting attendance and poll questions), (2) QI capacity (assessments completed by QI coaches), (3) use of QI tools (plan-do-check-act (PDCA) cycles started and completed) and (4) participant perceptions of acceptability (interviews and surveys).
RESULTS: Seven clinics from five primary care practices participated in the virtual QIC. Of the seven sites, five were community health centres, three were in rural counties and clinic size ranged from 1 to 7 physicians. For engagement, all practices had at least one member attend all online QIC meetings and most (9/11 (82%)) poll respondents reported meeting with their QI coach at least once per month. For QI capacity, practice-level scores showed improvements in foundational, intermediate and advanced QI work. For QI tools used, 26 PDCA cycles were initiated with 9 completed. Most (10/11 (91%)) survey respondents were satisfied with their virtual QIC experience. Twelve interviews revealed additional themes such as challenges in obtaining real-time data and working with multiple electronic medical record systems.
DISCUSSION: A virtual QIC conducted with independent primary care practices during COVID-19 resulted in high participation and satisfaction. QI capacity and use of QI tools increased over 1 year. These implementation outcomes suggest that virtual QICs may be an attractive alternative to engage independent practices in QI work.
Home is Where the Heart is: A Comparative Analysis of Home Birth Outcomes and Perceptions in the Developed World
Creators: name: McFarlane, Emma E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: Home birth rates are increasing throughout the developed world, which necessitates a
discussion regarding the outcomes and perceptions of home birth in developed countries. Home
birth outcomes and perceptions are widely varied, and many have noted that there exists a
relationship between a nation’s acceptance and integration of home birth into the standard model
of maternity care and the nation’s home birth outcomes. This paper discusses a sample of
developed countries, namely the United States, Canada, the United Kingdom, and the
Netherlands, and seeks to identify the relationship between a nation’s home birth outcomes and
its home birth perceptions. It was found that some countries, such as the United States, are
reluctant to integrate home birth into the standard model of maternity care, and also have poor
home birth outcomes. Countries like the Netherlands, by contrast, have created a standard
maternity system that embraces and supports home birth. Home birth outcomes in these countries
are exceptional. However, it was also found that no matter where a woman lives, the home birth
is associated with fewer medical interventions, high rates of physiologic birth, and a strong sense
of empowerment and autonomy. By comparing and contrasting home birth outcomes and
perceptions in nations around the globe, our understanding of this growing phenomenon
improves drastically and it becomes possible to create safer, better-integrated home birth
systems.
On the Order of $a$ modulo $n$ on Average
Creators: name: Kim, Sungjin
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: Let $a>1$ be an integer. Denote by $l_a(n)$ the multiplicative order of $a$ modulo integer $n\geq 1$. We prove that there is a positive constant $δ$ such that if $x^{1-δ}\log^3 x = o(y)$, then $$ \frac1y \sum_{a
Per un'edizione digitale del romanzo Suo marito di Luigi Pirandello
Creators: name: Cacciatore, Giulia
Publisher: name: Zenodo
Year: 2023
Subjects: edizione critica digitale
Codifica XML/TEI
Luigi Pirandello

description: Edizione digitale in XML/TEI dei paragrafi 1 e 2 del terzo capitolo del romanzo Suo marito (1911) di Luigi Pirandello
Lineament analysis and inference of geologic structure: examples from the Balcones Ouachita trend of Texas
Creators: name: Caran, S. Christopher
name: Woodruff, C. M.
name: Thompson, Eric J.
Publisher: name: University of Texas at Austin. Bureau of Economic Geology
Year: 1982
Subjects: Faults (Geology)
Geology, Structural

description: Bureau Publication GC8201 - to purchase a print copy please go to: https://store.beg.utexas.edu/geologic-circulars/467-gc8201.html Tx Doc no. : Z, UA220.7, G292, 82-1. Reprinted from Transactions of the Gulf Coast Association of Geological Societies, Vol. XXXI, 1981
description: Lineaments perceived in remotely sensed images are reliable indicators of geologic structure. Lineaments on ten Landsat multispectral scanner images (band 5; 1:250,000 scale) were mapped covering the Ouachita/Balcones-Luling-Mexia-Talco structural trend between the Rio Grande and Red river in Texas. More than 5,000 lineaments were perceived in these images. Maps depicting the lineaments (individually and in various combinations) were compared with maps of structural/ tectonic features and geothermal gradient contours, noting instances of apparent correlation among these themes. Lineaments are correlative with the individual faults and the aggregate fault patterns of the Baicones, Luling, Mexia, and Talco fault zones, Transverse lineaments, which trend almost perpendicular to these fault zones, mark the northernmost extent of the Balcones fault system and outline carbonate piatforms, such as the Belton High/Moffat Mound trend and the San Marcos arch. Transverse lineaments are coincident also with the axes of the buried Chittim and Preston anticlines and with the flanks of the Sherman and Round Rock synclines. Numerous salt domes occur at depth in the western part of the east Texas basin near the trend; many of these domes, particularly those in Henderson, Anderson, and Freestone Counties, are found along and at the intersection of major lineament zones where the concentration of individuai lineaments is greatest. Most of the buried Late Crelaceocs volcanoes of central Texas near Austin lie along northeast southwest- trending lineament zones; the altered pyroclastic rocks and associated beachrock facies at many of these volcanoes are hydrocarbon reservoirs. The orientation and spacing of geothermal gradient contour lines ("isograds") also correspond to major structures and thus, to the pattern of lineaments throughout the region. Correlation of (1)individual lineaments, zones of cortiguous or nearly parallel lineaments, and areas of homogeneous lineament density and orientation to (2) surface and subsurface structure and (3) geothermal,'isograd" patterns indicates that lineament analysis has many potential applications to regional mineral resource assessment.
MS Gr. class. c. 6 1261
Creators: name: Oxyrhynchus Papyri
Publisher: name: University of Oxford
Year: 2023
Subjects: classificationCode: 470316
subject: Latin and classical Greek languages

description: P.Herc. 1479 fr. 8 col. 2. Epicurus, De natura 28
Drawing by Carlo Orazi
Healthcare transition readiness of families of youth with cystic fibrosis during COVID-19: A correlational multicenter analysis
Creators: name: Goralski, Jennifer L.
name: Díaz-González de Ferris, Maria E.
name: Girdwood, Tyra C.
name: Lynn, Mary R.
name: Kainz, Kirsten
name: Nasr, Samya Z.
name: Toles, Mark P.
name: Dellon, Elisabeth P.
name: Silva, Susan G.
name: Uluer, Ahmet
Publisher: name: Elsevier
Year: 2024

description: Background Enhancing family readiness for the healthcare transition (HCT) to adult-focused care can help adolescents and young adults (AYA) thrive in adulthood. We aimed to explore modifiable and non-modifiable individual, family, and healthcare factors associated with HCT readiness of AYA among families of AYA with cystic fibrosis (CF) during COVID-19. Methods A multi-site, cross-sectional design was used and an online survey was deployed among families and their AYA from three US pediatric CF centers. The STARx Transition Readiness Questionnaire assessed caregiver- and AYA-perceived HCT readiness of AYA. Results Caregivers (N = 71) and their AYA with CF (N = 33, aged 12–21 years) perceived moderately high HCT readiness of AYA. Caregiver resilience was a significant (p = 0.006), family-level factor correlated with caregiver-perceived HCT readiness. Conclusions Families perceived similar levels of AYA readiness for adult-focused care. Caregiver resilience is an important, modifiable family-level factor for targeted interdisciplinary interventions aimed at enhancing HCT processes during COVID-19.
Correction: A qualitative assessment of barriers and facilitators of telemedicine volunteerism during the COVID-19 pandemic in India
Creators: name: Westgard, Christopher M.
name: Barnhardt, Sharon
name: D’Souza, Karishma
name: Singh, Saksham
Publisher: name: Springer Nature
Year: 2024

description: Corrects "A qualitative assessment of barriers and facilitators of telemedicine volunteerism during the COVID-19 pandemic in India "
Optimal quantum algorithm for polynomial interpolation
Creators: name: Childs, Andrew M.
name: van Dam, Wim
name: Hung, Shih-Han
name: Shparlinski, Igor E.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Computational Complexity (cs.CC)
subject: Cryptography and Security (cs.CR)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We consider the number of quantum queries required to determine the coefficients of a degree-d polynomial over GF(q). A lower bound shown independently by Kane and Kutin and by Meyer and Pommersheim shows that d/2+1/2 quantum queries are needed to solve this problem with bounded error, whereas an algorithm of Boneh and Zhandry shows that d quantum queries are sufficient. We show that the lower bound is achievable: d/2+1/2 quantum queries suffice to determine the polynomial with bounded error. Furthermore, we show that d/2+1 queries suffice to achieve probability approaching 1 for large q. These upper bounds improve results of Boneh and Zhandry on the insecurity of cryptographic protocols against quantum attacks. We also show that our algorithm's success probability as a function of the number of queries is precisely optimal. Furthermore, the algorithm can be implemented with gate complexity poly(log q) with negligible decrease in the success probability. We end with a conjecture about the quantum query complexity of multivariate polynomial interpolation.
description: 17 pages, minor improvements, added conjecture about multivariate interpolation
Deconstructing Breast Cancer Heterogeneity: Clinical Implications for Women with Basal-like Tumors
Creators: name: Rattani, Nabila Siraj
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Breast cancer is a heterogeneous disease comprising five major subtypes including luminal A, luminal B, HER2, basal-like, and normal breast-like tumors. Of the five subtypes of breast cancer, the basal-like subtype has the shortest survival and poorest prognosis. This subtype accounts for 10-20% of all breast cancers and is particularly problematic due to its aggressive nature. Moreover, these tumors currently have limited treatment options, due in part to the absence of growth factor receptors ER, PR, and HER2, which are often used as clinical targets in breast cancer therapies. A review of the literature was conducted using multiple databases, journal publications, and citation indices to comprehensively understand the genetic, epigenetic, and environmental factors contributing to the basal-like subtype. Beginning with a diagnosis of basal-like breast cancer, through aggressive treatment and post-treatment follow-up, oncology nurses play a pivotal role in providing holistic care and support for these patients. Therefore, it is imperative that they understand the complexity of the clinical presentation, as well as the current therapies and the underlying biology of this cancer subtype.
التباين المكاني لجرائم الجنايات بشعبية الجبل الأخضر - ليبيا
Creators: name: ALNAAS, JAMAL
Publisher: name: figshare
Year: 2023
Subjects: Earth system sciences
Other earth sciences not elsewhere classified

description: التباين المكاني لجرائم الجنايات بشعبية الجبل الأخضر - ليبيا
The Unintended Consequences of Organizations' Gender Strategies
Creators: name: Smallets, Stephanie
name: Tost, Leigh
name: Villafuerte, Andrea
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Social Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology

description: Our third study in this research program; Specifically, a field survey used to investigate the effects of gender strategies on psychological safety in a real-world context.
Play or science?: a study of learning and framing in crowdscience games
Creators: name: Lieberoth, Andreas
name: Pedersen, Mads Kock
name: Sherson, Jacob
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics Education (physics.ed-ph)
subject: Computers and Society (cs.CY)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Crowdscience games may hold unique potentials as learning opportunities compared to games made for fun or education. They are part of an actual science problem solving process: By playing, players help scientists, and thereby interact with real continuous research processes. This mixes the two worlds of play and science in new ways. During usability testing we discovered that users of the crowdscience game Quantum Dreams tended to answer questions in game terms, even when directed explicitly to give science explanations.We then examined these competing frames of understanding through a mixed correlational and grounded theory analysis. This essay presents the core ideas of crowdscience games as learning opportunities, and reports how a group of players used "game", "science" and "conceptual" frames to interpret their experience. Our results suggest that oscillating between the frames instead of sticking to just one led to the largest number of correct science interpretations, as players could participate legitimately and autonomously at multiple levels of understanding.
description: 26 pages, 3 figures
Implementation of NCCARE360, a Digital Statewide Closed-Loop Referral Platform to Improve Health and Social Care Coordination: Evidence from the North Carolina COVID-19 Support Services Program
Creators: name: McNeil, Shemecka
name: McNerney, Lisa
name: Pitcher, Ariana
name: Sangvai, Dev
name: Granger, Bradi B.
name: McPeek Hinz, Eugenia
name: Prvu Bettger, Janet
name: Drake, Connor
name: Rader, Abigail
name: Wertman, Eleanor
name: Avery, Carolyn
name: Granados, Isa
name: Shepherd-Banigan, Megan
name: Purakal, John
name: Bleser, William K.
name: Spratt, Susan
name: Tenenbaum, Elena
name: Mortiboy, Marissa
Publisher: name: North Carolina Institute of Medicine
Year: 2024

description:  Introduction Efforts to improve population health by being responsive to patients’ social and economic conditions will benefit from care models and technologies that assess and address unmet social needs. In 2019, NCCARE360 launched in North Carolina as the first state­wide digital care coordination network to “close the loop” on referrals between community-based organizations (CBOs), health service providers, and social service agencies. The platform creates a shared network for sending and receiving electronic referrals and track client outcomes.   Methods As a case study, we compare NCCARE360 resolution rates for community resource referrals originating from a large integrated health system primarily in Durham County from September 1, 2020, through February 28, 2021. In the first year, COVID-19 Support Ser­vices Program (COVID-SSP) funding was available to reimburse associated CBOs for providing food assistance and case management services. We compared this with the same period the following year after funds had been exhausted. We present frontline implementation experiences and highlight opportunities, challenges, and recommendations for NCCARE360 implementation.   Results Multi-level considerations for individual end users, organizations adopting the platform, and policymakers are presented. Addi­tionally, we find that when COVID-SSP funding was available, more referrals were placed (3,220 cases) and referrals were more likely to be resolved (88% resolution rate) when compared to the same time frame when funds were no longer available (860 cases; 30% resolution rate). These results underscore the importance of reimbursement mechanisms and funding.   Limitations The examination of referral rates is observational and may not generalize to other contexts.   Conclusion The shift to value-based care is an opportunity to embrace structural solutions to health and social care fragmentation. There is also an opportunity to realize the potential of NCCARE360 and efforts like it to contain costs and improve health outcomes and equity.
Supplemental materials for preprint: All journal articles evaluating the origin or epidemiology of SARS-CoV-2 that utilize the RaTG13 bat strain genomics are potentially flawed and should be retracted.
Creators: name: Bengston, Dean
Publisher: name: Open Science Framework
Year: 2022
Subjects: subject: Clinical Epidemiology
subject: Organisms
subject: Diseases
subject: Public Health
subject: Medicine and Health Sciences
subject: Virus Diseases
subject: Viruses
subject: Bioethics and Medical Ethics
subject: BtCov/4991
subject: COVID-19
subject: epidemiology
subject: RaTG13
subject: SARS-CoV-2

description: Recent SARS-CoV-2 epidemiological origin studies have made their conclusion based-in-part by analyzing a bat coronavirus strain that most closely matches SARS-CoV-2 called RaTG13. However, the origins of this strain are obfuscated and therefore the genomics of the strain cannot be trusted, especially in context of determining the origin of SARS-CoV-2.
Peculiar Velocity Constraints from Five-Band SZ Effect Measurements Towards RX J1347.5-1145 with MUSIC and Bolocam from the CSO
Creators: name: Sayers, Jack
name: Zemcov, Michael
name: Glenn, Jason
name: Golwala, Sunil R.
name: Maloney, Philip R.
name: Siegel, Seth R.
name: Wheeler, Jordan
name: Bockstiegel, Clint
name: Brugger, Spencer
name: Czakon, Nicole G.
name: Day, Peter K.
name: Downes, Thomas P.
name: Duan, Ran P.
name: Gao, Jiansong
name: Hollister, Matthew I.
name: Lam, Albert
name: LeDuc, Henry G.
name: Mazin, Benjamin A.
name: McHugh, Sean G.
name: Miller, David A.
name: Mroczkowski, Tony K.
name: Noroozian, Omid
name: Nguyen, Hien T.
name: Radford, Simon J.
name: Schlaerth, James A.
name: Vayonakis, Anastasios
name: Wilson, Philip R.
name: Zmuidzinas, Jonas
Publisher: name: arXiv
Year: 2015
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present Sunyaev-Zel'dovich (SZ) effect measurements from wide-field images towards the galaxy cluster RX J1347.5-1145 obtained from the Caltech Submillimeter Observatory with the Multiwavelength Submillimeter Inductance Camera (MUSIC) at 147, 213, 281, and 337 GHz and with Bolocam at 140 GHz. As part of our analysis, we have used higher frequency data from Herschel-SPIRE and previously published lower frequency radio data to subtract the signal from the brightest dusty star-forming galaxies behind RX J1347.5-1145 and from the AGN in RX J1347.5-1145's BCG. Using these five-band SZ effect images, combined with X-ray spectroscopic measurements of the temperature of the intra-cluster medium (ICM) from Chandra, we constrain the ICM optical depth to be $τ_e = 7.33^{+0.96}_{-0.97} \times 10^{-3}$ and the ICM line of sight peculiar velocity to be $v_{pec} = -1040^{+870}_{-840}$ km s$^{-1}$. The errors for both quantities are limited by measurement noise rather than calibration uncertainties or astrophysical contamination, and significant improvements are possible with deeper observations. Our best-fit velocity is in good agreement with one previously published SZ effect analysis and in mild tension with the other, although some or all of that tension may be because that measurement samples a much smaller cluster volume. Furthermore, our best-fit optical depth implies a gas mass slightly larger than the Chandra-derived value, implying the cluster is elongated along the line of sight.
description: Accepted for publication in ApJ