cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Centripetal Acceleration Reaction: An Effective and Robust Mechanism for Flapping Flight in Insects
Creators: name: Mittal, Rajat
name: Hedrick, Tyson L.
name: Zhang, Chao
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Despite intense study by physicists and biologists, we do not fully understand the unsteady aerodynamics that relate insect wing morphology and kinematics to lift generation. Here, we formulate a force partitioning method (FPM) and implement it within a computational fluid dynamic model to provide an unambiguous and physically insightful division of aerodynamic force into components associated with wing kinematics, vorticity, and viscosity. Application of the FPM to hawkmoth and fruit fly flight shows that the leading-edge vortex is the dominant mechanism for lift generation for both these insects and contributes between 72–85% of the net lift. However, there is another, previously unidentified mechanism, the centripetal acceleration reaction, which generates up to 17% of the net lift. The centripetal acceleration reaction is similar to the classical inviscid added-mass in that it depends only on the kinematics (i.e. accelerations) of the body, but is different in that it requires the satisfaction of the no-slip condition, and a combination of tangential motion and rotation of the wing surface. Furthermore, the classical added-mass force is identically zero for cyclic motion but this is not true of the centripetal acceleration reaction. Furthermore, unlike the lift due to vorticity, centripetal acceleration reaction lift is insensitive to Reynolds number and to environmental flow perturbations, making it an important contributor to insect flight stability and miniaturization. This force mechanism also has broad implications for flow-induced deformation and vibration, underwater locomotion and flows involving bubbles and droplets.
Translation of Michael Sadowsky's paper "The differential equations of the Möbius band"
Creators: name: Hinz, Denis F.
name: Fried, Eliot
Publisher: name: arXiv
Year: 2014
Subjects: subject: History and Overview (math.HO)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: This article is a translation of Michael Sadowsky's original paper "Die Differentialgleichungen des Möbiusschen Bandes." in Jahresbericht der Deutschen Mathematiker-Vereinigung 39 (2. Abt. Heft 5/8, Jahresversammlung vom 16. bis 23. September), 49-51 (1929), which is a short version of his paper "Theorie der elastisch biegsamen undehnbaren Bänder mit Anwendungen auf das Möbiussche Band" in 3. internationaler Kongress für technische Mechanik, Stockholm, 1930.
description: 4 pages, to appear in a special volume of the Journal of Elasticity entitled "The Mechanics of Ribbons and M\"obius Bands", citations of this translation should refer also to Sadowsky's original paper, as cited in the Abstract
A connected component-based method for efficiently integrating multiscale $N$-body systems
Creators: name: Jänes, Jürgen
name: Pelupessy, Federico I.
name: Zwart, Simon F. Portegies
Publisher: name: arXiv
Year: 2014
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: We present a novel method for efficient direct integration of gravitational N-body systems with a large variation in characteristic time scales. The method is based on a recursive and adaptive partitioning of the system based on the connected components of the graph generated by the particle distribution combined with an interaction-specific time step criterion. It uses an explicit and approximately time-symmetric time step criterion, and conserves linear and angular momentum to machine precision. In numerical tests on astrophysically relevant setups, the method compares favourably to both alternative Hamiltonian-splitting integrators as well as recently developed block time step-based GPU-accelerated Hermite codes. Our reference implementation is incorporated in the HUAYNO code, which is freely available as a part of the AMUSE framework.
description: 12 pages, 8 figures, accepted for A&A
title: Ο ρόλος της νοσηρότητας στην ηλικία της συνταξιοδότησης πριν και μετά την οικονομική κρίση στην Ελλάδα και σε χώρες της Ευρώπης
title: Morbidity and age at retirement before and following the economic crisis in Greece and other European countries
titleType: AlternativeTitle
Creators: name: Πετρά, Ελένη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: Ασφάλιση
subject: Υγεία
subject: Μοντέλα
subject: Περιγραφική ανάλυση
subject: Νοσηρότητα
subject: Συνταξιοδότηση

description: Σκοπός της παρούσας διπλωματικής εργασίας είναι η διεύρυνση της συσχέτισης μεταξύ των παραγόντων υγείας και της συνταξιοδότησης της Ελλάδας και άλλων χωρών της Ευρώπης πριν και μετά την οικονομική κρίση. Στο πρώτο κεφάλαιο παρατίθεται μία ανάλυση όσον αφορά τον θεσμό τη υγείας ως συνταγματικό και κοινωνικό δικαίωμα. Στο ίδιο κεφάλαιο, γίνεται λόγος για το συνταξιοδοτικό σύστημα στην Ελλάδα και για τον όρο νοσηρότητα. Στο δεύτερο κεφάλαιο, γίνεται η βασική ανάλυση και η περιγραφή του αντικειμένου της εργασίας: η μελέτη της επίδρασης της νοσηρότητας στην ηλικία της συνταξιοδότησης. Στη συνέχεια, με τη βοήθεια μεθόδων περιγραφικής στατιστικής ανάλυσης, παρουσιάζονται αποτελέσματα της έρευνας SHARE. Στο τρίτο κεφάλαιο, γίνεται αναφορά στη διεύρυνση της επίδρασης διαφόρων παραγόντων στην ηλικία της συνταξιοδότησης με χρήση της Λογιστικής Παλινδρόμησης. Τέλος, στο κεφάλαιο τέσσερα παρατίθενται συνοπτικά τα κύρια αποτελέσματα της ανάλυσης.
Resolution of different beam size read-out systems at PITZ
Creators: name: Tanha, Mohammad
name: DESY
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2010
Subjects: Unveröffentlichte Hochschulschrift

description: Masterarbeit, Universität Siegen, 2010; 58 pp. (2010). = Masterarbeit, Universität Siegen, 2010
Changes in HIV Outcomes Following Depression Care in a Resource-Limited Setting: Results from a Pilot Study in Bamenda, Cameroon
Creators: name: Whetten, Rachel
name: Gaynes, Bradley N.
name: Arrey, Charles Kefie
name: O’Donnell, Julie K.
name: Njamnshi, Alfred K.
name: Atashili, Julius
name: Ndumbe, Peter
name: Tabenyang, Mbu Eyongetah
name: Whetten, Kathryn
name: Pence, Brian W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BackgroundLittle is known about how improved depression care affects HIV-related outcomes in Africa. In a sample of depressed HIV patients in a low income, sub-Saharan country, we explored how implementing measurement-based antidepressant care (MBC) affected HIV outcomes over 4 months of antidepressant treatment.MethodsAs part of a project adapting MBC for use in Cameroon, we enrolled 41 depressed HIV patients on antiretroviral therapy in a pilot study in which a depression care manager (DCM) provided an outpatient HIV clinician with evidence-based decision support for antidepressant treatment. Acute depression management was provided for the first 12 weeks, with DCM contact every 2 weeks and HIV clinician appointments every 4 weeks. We measured HIV clinical and psychiatric outcomes at 4 months.ResultsParticipants were moderately depressed at baseline (mean Patient Health Questionnaire [PHQ] score = 14.4, range 13.1, 15.6). All HIV clinical outcomes improved by four month follow-up: mean (range) CD4 count improved from 436 (2, 860) to 452 (132, 876), mean (range) log-viral load decreased from 4.02 (3.86, 4.17) to 3.15 (2.81, 3.49), the proportion with virologic suppression improved from 0% to 18%, mean (range) HIV symptoms decreased from 6.4 (5.5, 7.3) to 3.1 (2.5, 3.7), the proportion reporting good or excellent health improved from 18% to 70%, and the proportion reporting any missed ARV doses in the past month decreased from 73% to 55%. Concurrently, psychiatric measures improved. The mean (range) PHQ score decreased from 14.4 (13.1, 15.6) to 1.6 (0.8, 2.4) and 90% achieved depression remission, while mean maladaptive coping style scores decreased and mean adaptive coping scores and self-efficacy scores improved.ConclusionIn this pilot study of an evidence-based depression treatment intervention for HIV-infected patients in Cameroon, a number of HIV behavioral and non-behavioral health outcomes improved over 4 months of effective depression treatment. These data are consistent with the hypothesis that better depression care can lead to improved HIV outcomes.
Descriptions of new species of hymenopterous insects collected by Mr. A. R. Wallace at Celebes. (Part Formicidae)
Creators: name: Smith, F.
Publisher: name: Zenodo
Year: 1860
Subjects: Biodiversity
Taxonomy

description: 1. Odontomachus simillimus, Smith, Cat. Hym. Ins. Form. p. 80, pl. 5. figs. 8, 9. This species closely resembles O. hœmatodes, but may be known by the following differences: the mandibles are distinctly serrated throughout the entire length on the inner margin; the head narrower and the antenna; shorter in the worker; in the female the neuration of the wings is different. Hab. Celebes (Makassar); Fidjee Islands; Ceylon.
description: Published as part of Smith, F., 1860, Descriptions of new species of hymenopterous insects collected by Mr. A. R. Wallace at Celebes. (Part Formicidae), pp. 57-93 in Journal of the Proceedings of the Linnean Society of London, Zoology 5 on page 72
On the evolution of gas clouds exposed to AGN radiation. I. Three-dimensional radiation hydrodynamic simulations
Creators: name: Namekata, Daisuke
name: Umemura, Masayuki
name: Hasegawa, Kenji
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We perform three-dimensional radiation hydrodynamic simulations of uniform dusty gas clouds irradiated by an active galactic nucleus (AGN) to investigate the dependence of evolution of clouds on the ionization parameter $\mathcal{U}$ and the Str{ö}mgren number $\mathcal{N}_{S}$. We find that the evolution can be classified into two cases depending on $\mathcal{U}$. In low $\mathcal{U}$ cases ($\mathcal{U}\approx 10^{-2}$), the evolution is mainly driven by photo-evaporation. A approximately spherically-symmetric evaporation flow with velocity of $100\operatorname{-}150\;\mathrm{km\;s^{-1}}$ is launched from the irradiated face. The cloud is compressed by a D-type shock with losing its mass due to photo-evaporation and is finally turned into a dense filament by $t\lesssim 1.5t_{\mathrm{sc}}$. In high $\mathcal{U}$ cases ($\mathcal{U}\approx 5\times 10^{-2}$), radiation pressure suppresses photo-evaporation from the central part of the irradiated face, reducing photo-evaporation rate. A evaporation flow from the outskirts of the irradiated face is turned into a high velocity ($\lesssim 500\;\mathrm{km\;s^{-1}}$) gas wind because of radiation pressure on dust. The cloud is swept by a radiation pressure-driven shock and becomes a dense gas disk by $t\approx t_{\mathrm{sweep}}$. Star formation is expected in these dense regions for both cases of $\mathcal{U}$. We discuss the influences of the AGN radiation on the clumpy torus. A simple estimate suggests that the clumps are destroyed in timescales shorter than their orbital periods. For the clumpy structure to be maintained over long period, the incident radiation field needs to be sufficiently weaken for most of the clumps, or, some mechanism that creates the clumps continuously is needed.
description: 33 pages, 36 figures, 6 tables; accepted for publication in Monthly Notices of the Royal Astronomical Society
Isolated Neutron Stars: recent results and prospects for Athena
Creators: name: Borghese, Alice
Publisher: name: Zenodo
Year: 2022

description: Neutron stars have shown diverse characteristics, leading us to classify them into different classes. In this talk, I will focus on the observational properties of isolated neutron stars: from magnetars, the strongest magnets we know of, to central compact objects, the so-called anti-magnetars, stopping by the rotation-powered pulsars and X-ray dim isolated neutron stars. Moreover, I will show you how some sources have exhibited features straddling those of different groups. I will then finish with some considerations on possible evolutionary links between neutron star families and future prospects for Athena.
Changes in Prices After an Excise Tax to Sweetened Sugar Beverages Was Implemented in Mexico: Evidence from Urban Areas
Creators: name: Rivera-Dommarco, Juan Angel
name: Colchero, M. Arantxa
name: Unar-Munguía, Mishel
name: Salgado, Juan Carlos
name: Molina, Mariana
name: Ng, Shuwen
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: In 2014 an excise tax to non-alcoholic sweetened beverages (SSB) was implemented in Mexico. The objective of this paper is to study whether and to what degree these taxes passed-through onto SSB prices in urban areas overall and by region, type of beverage and package size. Prices were obtained from the National Institute of Statistics and Geography from 2011 to 2014. We applied a pre-post quasi-experimental approach using fixed effects models. In sensitivity analysis we applied other model specifications to test the robustness of the findings and we also present weighted estimations based on household purchases. The dependent variables are real prices of a specific beverage category; the main independent variables are dummies for each month of 2014, and the models adjust for time trends and seasonality. Results suggest that the SSB tax passed along to consumers for all SSBs and we found overshifting for the carbonated SSBs. A greater effect is seen among the small package sizes, and we see heterogeneous effects by region. Estimating the effect of the tax on prices is important to understand the potential effect on consumption.
title: Cyprus Report. Sustainable Governance Indicators 2022
Creators: name: Christophorou, Christophoros
name: Axt, Heinz-Jürgen
name: Karadag, Roy
Publisher: name: Bertelsmann Stiftung
Year: 2022
Subjects: Governance
Democracy
Regierungshandeln
Demokratie

description: The sustained course of Cyprus’s economic growth was abruptly interrupted by the COVID-19 crisis, which had a significant impact on the country’s main sectors, tourism and construction, among others. Recovery started at the beginning of and continued through 2021. The strengthening of the economy prior to 2020 contributed to the relatively good management of the pandemic.
title: Investigating organised crime - perspectives from within the police: A case study on business techniques and how can they be applied to analysing OCGs in a police setting
Creators: name: Allen, C
Publisher: name: Liverpool John Moores University
Year: 2023

description: The argument central to this thesis is that business analysis techniques can be transposed from use in a legitimate business situation to a criminal investigative standpoint. In an investigative situation, business analysis techniques can enhance investigation and provide insight into strategy development against organised crime groups (OCGs). Much of this research was conducted while working as a volunteer for City of London Police. The methodology is multi-faceted and involves seven key strands: 1) Creation of a framework to analyse which key questions posed within current business analysis techniques are translatable to an organised crime context, 2) Creation of initial toolkit based on results of methodology 1. 3) Trial and improvement of initial toolkit by the author on a range of historical cases. 4) A survey distributed to the Regional Organised Crime Unit (ROCU) network to determine strengths and weaknesses of the toolkit and verify the core research concept. 5) In depth interviews conducted with law enforcement and academia for the same purpose as strand 4. 6) Further trial and adaption of the of toolkit on live cases following amendments by myself made after analysis of the results of methodologies 4 and 5. 7) The seventh strand involved detailed feedback from a series of live pilot on cases conducted by specially selected analysts in several law enforcement agencies. Case study data was obtained from several law enforcement agencies with permission for academic analysis, but not for disclosure into the public domain; therefore, the results of the case study analysis, but not the raw intelligence itself, will be included in this submission. Because of the unique nature of each organised crime investigation, the quality of the intelligence data in each case study differs depending on the level of access granted and the level of intelligence granted to the lead law enforcement agency. To counteract this the thesis’ central argument was tested on organised crime groups that were involved in a variety of criminal activities including: fraud, drugs and counterfeiting. Following the conclusion of this methodological approach, the evidence amassed has allowed concrete conclusions to be drawn surrounding the applicability of business analysis techniques to enhance analysis of Organised Crime Groups (OCGs). These conclusions have been used to create a series of questions, which has the potential to make a tangible difference in the way in which investigative strategies are developed.
Translation of Michael Sadowsky's paper "An elementary proof for the existence of a developable Möbius band and the attribution of the geometric problem to a variational problem"
Creators: name: Hinz, Denis F.
name: Fried, Eliot
Publisher: name: arXiv
Year: 2014
Subjects: subject: History and Overview (math.HO)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: This article is a translation of Michael Sadowsky's original paper "Ein elementarer Beweis für die Existenz eines abwickelbaren Möbiusschen Bandes und die Zurückführung des geometrischen Problems auf ein Variationsproblem." which appeared in Sitzungsberichte der Preussischen Akademie der Wissenschaften, physikalisch-mathematische Klasse, 17. Juli 1930, Mitteilung vom 26. Juni, 412-415. Published on September 12, 1930.
description: 5 pages, 3 figures, to appear in a special volume of the Journal of Elasticity entitled "The Mechanics of Ribbons and M\"obius Bands", citations of this translation should refer also to Sadowsky's original paper, as cited in the Abstract
The Equality of Longitudinal Processes across Sexual and Gender Diverse People
Creators: name: Derringer, Jaime
name: Ogolsky, Brian
name: Junkins, Eleanor J
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Personality and Social Contexts
subject: Developmental Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: diversity
subject: generalizability
subject: personality development
subject: relationship science
subject: subjective well-being

description: The present study will use data collected online, mostly on Instagram, from the longitudinal project, the POWER study, sampling across all gender and sexual identities. The goal of the project was to sample from underrepresented groups in romantic relationships research, and we were successful in getting a large number of sexual and gender minority participants as well as getting people of different education backgrounds and SES. For this research I will examine univariate and bivariate growth between the following constructs assessed monthly or every other month in our dataset—relationship power, Big Five, Agency-Communion, relationship satisfaction, social support, social isolation, discrimination, depression, and subjective well-being—for variables with 3 waves measured. Groups greater than 800 will have more precise estimation. In each case, the parameter of interest is the differences between groups with our hypotheses stating that we expect fewer differences and mostly similarities.
Descriptions of new species of hymenopterous insects collected by Mr. A. R. Wallace at Celebes. (Part Formicidae)
Creators: name: Smith, F.
Publisher: name: Zenodo
Year: 1860
Subjects: Biodiversity
Taxonomy

description: 1. Ponera geometrica, Smith, Proc. Linn. Soc. ii. p. 67. Hab. Celebes (Makassar). Singapore,
description: Published as part of Smith, F., 1860, Descriptions of new species of hymenopterous insects collected by Mr. A. R. Wallace at Celebes. (Part Formicidae), pp. 57-93 in Journal of the Proceedings of the Linnean Society of London, Zoology 5 on page 72
Additional file 1 of Single melatonin injection enhances the testicular artery hemodynamic, reproductive hormones, and semen parameters in German shepherd dogs
Creators: name: Salama, Ali
name: Abdelnaby, Elshymaa A.
name: Emam, Ibrahim A.
name: Fathi, Mohamed
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Additional file 1.
Characteristics of Internet Addiction/Pathological Internet Use in U.S. University Students: A Qualitative-Method Investigation
Creators: name: Li, Wen
name: O’Brien, Jennifer E.
name: Snyder, Susan M.
name: Howard, Matthew O.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Studies have identified high rates and severe consequences of Internet Addiction/Pathological Internet Use (IA/PIU) in university students. However, most research concerning IA/PIU in U.S. university students has been conducted within a quantitative research paradigm, and frequently fails to contextualize the problem of IA/PIU. To address this gap, we conducted an exploratory qualitative study using the focus group approach and examined 27 U.S. university students who self-identified as intensive Internet users, spent more than 25 hours/week on the Internet for non-school or non-work-related activities and who reported Internet-associated health and/or psychosocial problems. Students completed two IA/PIU measures (Young’s Diagnostic Questionnaire and the Compulsive Internet Use Scale) and participated in focus groups exploring the natural history of their Internet use; preferred online activities; emotional, interpersonal, and situational triggers for intensive Internet use; and health and/or psychosocial consequences of their Internet overuse. Students’ self-reports of Internet overuse problems were consistent with results of standardized measures. Students first accessed the Internet at an average age of 9 (SD = 2.7), and first had a problem with Internet overuse at an average age of 16 (SD = 4.3). Sadness and depression, boredom, and stress were common triggers of intensive Internet use. Social media use was nearly universal and pervasive in participants’ lives. Sleep deprivation, academic under-achievement, failure to exercise and to engage in face-to-face social activities, negative affective states, and decreased ability to concentrate were frequently reported consequences of intensive Internet use/Internet overuse. IA/PIU may be an underappreciated problem among U.S. university students and warrants additional research.
Number-phase entropic squeezing and nonclassical properties of a three-level atom interacting with a two-mode field: Intensity-dependent coupling, deformed Kerr medium and detuning effects
Creators: name: Faghihi, M J
name: Tavassoly, M K
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this paper, we follow our presented model in J. Opt. Soc. Am. B {\bf 30}, 1109--1117 (2013), in which the interaction between a $Λ$-type three-level atom and a quantized two-mode radiation field in a cavity in the presence of nonlinearities is studied. After giving a brief review on the procedure of obtaining the state vector of the atom-field system, some further interesting and important physical features (which are of particular interest in the quantum optics field of research) of the whole system state, i.e., the number-phase entropic uncertainty relation (based on the two-mode Pegg-Barnett formalism) and some of the nonclassicality signs consist of sub-Poissonian statistics, Cauchy-Schwartz inequality and two kinds of squeezing phenomenon are investigated. During our presentation, the effects of intensity-dependent coupling, deformed Kerr medium and the detuning parameters on the depth and domain of each of the mentioned nonclassical criteria of the considered quantum system are studied, in detail. It is shown that each of the mentioned nonclassicality aspects can be obtained by appropriately choosing the related parameters.
description: 16 pages
Charge Shielding of PIP2 by Cations Regulates Enzyme Activity of Phospholipase C
Creators: name: Jung, Seung-Ryoung
name: Huang, Weigang
name: Zhang, Qisheng
name: Koh, Duk-Su
name: Seo, Jong Bae
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) of the plasma membrane by phospholipase C (PLC) generates two critical second messengers, inositol-1,4,5-trisphosphate and diacylglycerol. For the enzymatic reaction, PIP2 binds to positively charged amino acids in the pleckstrin homology domain of PLC. Here we tested the hypothesis that positively charged divalent and multivalent cations accumulate around the negatively charged PIP2, a process called electrostatic charge shielding, and therefore inhibit electrostatic PIP2-PLC interaction. This charge shielding of PIP2 was measured quantitatively with an in vitro enzyme assay using WH-15, a PIP2 analog, and various recombinant PLC proteins (β1, γ1, and δ1). Reduction of PLC activity by divalent cations, polyamines, and neomycin was well described by a theoretical model considering accumulation of cations around PIP2 via their electrostatic interaction and chemical binding. Finally, the charge shielding of PIP2 was also observed in live cells. Perfusion of the cations into cells via patch clamp pipette reduced PIP2 hydrolysis by PLC as triggered by M1 muscarinic receptors with a potency order of Mg2+ < spermine4+ < neomycin6+. Accumulation of divalent cations into cells through divalent-permeable TRPM7 channel had the same effect. Altogether our results suggest that Mg2+ and polyamines modulate the activity of PLCs by controlling the amount of free PIP2 available for the enzymes and that highly charged biomolecules can be inactivated by counterions electrostatically.
Direct mapping of nuclear shell effects in the heaviest elements
Creators: name: Ramirez, E. Minaya
name: Ackermann, D.
name: Blaum, K.
name: Block, M.
name: Droese, C.
name: Düllmann, Ch. E.
name: Dworschak, M.
name: Eibach, M.
name: Eliseev, S.
name: Haettner, E.
name: Herfurth, F.
name: Heßberger, F. P.
name: Hofmann, S.
name: Ketelaer, J.
name: Marx, G.
name: Mazzocco, M.
name: Nesterenko, D.
name: Novikov, Yu. N.
name: Plaß, W. R.
name: Rodríguez, D.
name: Scheidenberger, C.
name: Schweikhard, L.
name: Thirolf, P. G.
name: Weber, C.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: Quantum-mechanical shell effects are expected to strongly enhance nuclear binding on an "island of stability" of superheavy elements. The predicted center at proton number $Z=114,120$, or $126$ and neutron number $N=184$ has been substantiated by the recent synthesis of new elements up to $Z=118$. However the location of the center and the extension of the island of stability remain vague. High-precision mass spectrometry allows the direct measurement of nuclear binding energies and thus the determination of the strength of shell effects. Here, we present such measurements for nobelium and lawrencium isotopes, which also pin down the deformed shell gap at $N=152$.
description: 9 pages, 3 figures
Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis
Creators: name: Coll, Mar
name: Ginès, Pere
name: Affò, Silvia
name: Caballería, Joan
name: Morales-Ibanez, Oriol
name: Millán, Cristina
name: Rodrigo-Torres, Daniel
name: Arroyo, Vicente
name: Altamirano, José
name: Bataller, Ramón
name: Blaya, Delia
name: Sancho-Bru, Pau
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: Chronic liver diseases are characterized by a sustained inflammatory response in which chemokines and chemokine-receptors orchestrate inflammatory cell recruitment. In this study we investigated the role of the chemokine receptor CCR6 in acute and chronic liver injury. In the absence of liver injury Ccr6-/- mice presented a higher number of hepatic macrophages and increased expression of pro-inflammatory cytokines and M1 markers Tnf-α, Il6 and Mcp1. Inflammation and cell recruitment were increased after carbon tetrachloride-induced acute liver injury in Ccr6-/- mice. Moreover, chronic liver injury by carbon tetrachloride in Ccr6-/- mice was associated with enhanced inflammation and fibrosis, altered macrophage recruitment, enhanced CD4+ cells and a reduction in Th17 (CD4+IL17+) and mature dendritic (MHCII+CD11c+) cells recruitment. Clodronate depletion of macrophages in Ccr6-/- mice resulted in a reduction of hepatic pro-inflammatory and pro-fibrogenic markers in the absence and after liver injury. Finally, increased CCR6 hepatic expression in patients with alcoholic hepatitis was found to correlate with liver expression of CCL20 and severity of liver disease. In conclusion, CCR6 deficiency affects hepatic inflammatory cell recruitment resulting in the promotion of hepatic inflammation and fibrosis.
Childhood Adversity as a Predictor of Non-Adherence to Statin Therapy in Adulthood
Creators: name: Kivimäki, Mika
name: Korhonen, Maarit Jaana
name: Karlsson, Hasse
name: Brookhart, M. Alan
name: Kawachi, Ichiro
name: Vahtera, Jussi
name: Pentti, Jaana
name: Halonen, Jaana I.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: PurposeTo investigate whether adverse experiences in childhood predict non-adherence to statin therapy in adulthood.MethodsA cohort of 1378 women and 538 men who initiated statin therapy during 2008–2010 after responding to a survey on childhood adversities, was followed for non-adherence during the first treatment year. Log-binomial regression was used to estimate predictors of non-adherence, defined as the proportion of days covered by dispensed statin tablets <80%. In fully adjusted models including age, education, marital status, current smoking, heavy alcohol use, physical inactivity, obesity, presence of depression and cardiovascular comorbidity, the number of women ranged from 1172 to 1299 and that of men from 473 to 516, because of missing data on specific adversities and covariates.ResultsTwo in three respondents reported at least one of the following six adversities in the family: divorce/separation of the parents, long-term financial difficulties, severe conflicts, frequent fear, severe illness, or alcohol problem of a family member. 51% of women and 44% of men were non-adherent. In men, the number of childhood adversities predicted an increased risk of non-adherence (risk ratio [RR] per adversity 1.11, 95% confidence interval [CI] 1.01–1.21], P for linear trend 0.013). Compared with those reporting no adversities, men reporting 3–6 adversities had a 1.44-fold risk of non-adherence (95% CI 1.12–1.85). Experiencing severe conflicts in the family (RR 1.27, 95% CI 1.03–1.57]) and frequent fear of a family member (RR 1.27, 95% CI 1.00–1.62]) in particular, predicted an increased risk of non-adherence. In women, neither the number of adversities nor any specific type of adversity predicted non-adherence.ConclusionsExposure to childhood adversity may predict non-adherence to preventive cardiovascular medication in men. Usefulness of information on childhood adversities in identification of adults at high risk of non-adherence deserves further research.
Clinical Features of Reported Ethylene Glycol Exposures in the United States
Creators: name: Hladik, Gerald A.
name: Beuhler, Michael C.
name: Hu, Yichun
name: Falk, Ronald J.
name: Jobson, Meghan A.
name: Pendergraft, William F.
name: Hogan, Susan L.
name: Maxwell, Colin S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: BackgroundEthylene glycol is highly toxic and represents an important cause of poisonings worldwide. Toxicity can result in central nervous system dysfunction, cardiovascular compromise, elevated anion gap metabolic acidosis and acute kidney injury. Many states have passed laws requiring addition of the bittering agent, denatonium benzoate, to ethylene glycol solutions to reduce severity of exposures. The objectives of this study were to identify differences between unintentional and intentional exposures and to evaluate the utility of denatonium benzoate as a deterrent.Methods and FindingsUsing the National Poison Data System, we performed a retrospective analysis of reported cases of ethylene glycol exposures from January 2006 to December 2013. Outcome classification was summed for intentionality and used as a basis for comparison of effect groups. There were 45,097 cases of ethylene glycol exposures resulting in 154 deaths. Individuals more likely to experience major effects or death were older, male, and presented with more severe symptoms requiring higher levels of care. Latitude and season did not correlate with increased exposures; however, there were more exposures in rural areas. Denatonium benzoate use appeared to have no effect on exposure severity or number.ConclusionDeaths due to ethylene glycol exposure were uncommon; however, there were major clinical effects and more exposures in rural areas. Addition of denatonium benzoate was not associated with a reduction in exposures. Alternative means to deter ingestion are needed. These findings suggest the need to consider replacing ethylene glycol with alternative and less toxic agents.
Additional file 1 of Association of sex steroid hormones and new bone formation rate after iliac onlay grafting: a prospective clinical pilot study
Creators: name: Landwehr, Victoria Constanze
name: Fretwurst, Tobias
name: Heinen, Julia
name: Vach, Kirstin
name: Nelson, Katja
name: Nahles, Susanne
name: Iglhaut, Gerhard
Publisher: name: figshare
Year: 2022
Subjects: subject: Biophysics
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1. Supplement 1. Body mass index (BMI), 17β-estradiol, testosterone, sex hormone binding globulin and meannew bone formation (NBF) in female and male patients. Supplement 2. Reference ranges (a) of the body mass index (BMI), according to the World HealthOrganization (WHO, 2000), regardless of gender and (b) of the sex steroid hormone serumconcentrations according to the criteria of the Labor Berlin - Charité Vivantes GmbH.
Translation and interpretation of Michael Sadowsky's paper "Theory of elastically bendable inextensible bands with applications to the Möbius band"
Creators: name: Hinz, Denis F.
name: Fried, Eliot
Publisher: name: arXiv
Year: 2014
Subjects: subject: History and Overview (math.HO)
subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences

description: This article is a translation of Michael Sadowsky's original paper "Theorie der elastisch biegsamen undehnbaren Bänder mit Anwendungen auf das Möbiussche Band" in 3. internationaler Kongress für technische Mechanik, Stockholm, 1930. The translation is augmented by an Appendix containing an interpretation of the last section of Sadowsky's original paper including figures generated from recent numerical simulations.
description: 12 pages, 2 original figures, 2 supplementary figures, to appear in a special volume of the Journal of Elasticity entitled "The Mechanics of Ribbons and M\"obius Bands", citations of this translation should refer also to Sadowsky's original paper, as cited in the Abstract
Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC
Creators: name: Rosson, Gary B.
name: Jo, Heejoon
name: Walter, Vonn
name: Zhao, Xiaobei
name: Eberhard, David A.
name: Earp, H. Shelton
name: Salazar, Ashley H.
name: Patel, Nirali M.
name: Hayward, Michele C.
name: Siegel, Marni B.
name: Hayes, D. Neil
name: Moschos, Stergios J.
name: Weck, Karen E.
name: Yin, Xiaoying
name: Soloway, Matthew G.
name: Gulley, Margaret L.
name: Wang, Anyou
name: Zhang, Guosheng
name: Wilkerson, Matthew D.
name: Parker, Joel S.
name: Sharpless, Norman E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: The recent FDA approval of the MiSeqDx platform provides a unique opportunity to develop targeted next generation sequencing (NGS) panels for human disease, including cancer. We have developed a scalable, targeted panel-based assay termed UNCseq, which involves a NGS panel of over 200 cancer-associated genes and a standardized downstream bioinformatics pipeline for detection of single nucleotide variations (SNV) as well as small insertions and deletions (indel). In addition, we developed a novel algorithm, NGScopy, designed for samples with sparse sequencing coverage to detect large-scale copy number variations (CNV), similar to human SNP Array 6.0 as well as small-scale intragenic CNV. Overall, we applied this assay to 100 snap-frozen lung cancer specimens lacking same-patient germline DNA (07–0120 tissue cohort) and validated our results against Sanger sequencing, SNP Array, and our recently published integrated DNA-seq/RNA-seq assay, UNCqeR, where RNA-seq of same-patient tumor specimens confirmed SNV detected by DNA-seq, if RNA-seq coverage depth was adequate. In addition, we applied the UNCseq assay on an independent lung cancer tumor tissue collection with available same-patient germline DNA (11–1115 tissue cohort) and confirmed mutations using assays performed in a CLIA-certified laboratory. We conclude that UNCseq can identify SNV, indel, and CNV in tumor specimens lacking germline DNA in a cost-efficient fashion.
CYBER THREATS TO OT SYSTEMS IN THE ENERGY INDUSTRY
Creators: name: Pilarski, Grzegorz
name: Mikusek, Karolina
Publisher: name: Wiedza Obronna
Year: 2023

description: In today's economy, we can see a modern direction of action including the concept of technological and organizational transformation of enterprises, known as Industry 4.0. Significant changes are also taking place in the energy industry, where modifications in the use of infrastructure, systems of operational technology (OT) are noticeable. The aim of the article is to present the threats in the field of cyberattacks that can be carried out on this infrastructure within the mentioned sector.
description: Wiedza Obronna, Tom 283 Nr 2 (2023)
Comparative Value of Four Measures of Retention in Expert Care in Predicting Clinical Outcomes and Health Care Utilization in HIV Patients
Creators: name: Koeller, Jim M.
name: Copeland, Laurel A.
name: Frei, Christopher R.
name: Reveles, Kelly R.
name: Oramasionwu, Christine U.
name: Bollinger, Mary
name: Juday, Timothy R.
name: Jones, Xavier
name: Labreche, Matthew J.
name: Seekins, Daniel
name: Mortensen, Eric M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2015

description: This study compared the ability of four measures of patient retention in HIV expert care to predict clinical outcomes. This retrospective study examined Veterans Health Administration (VHA) beneficiaries with HIV (ICD-9-CM codes 042 or V08) receiving expert care (defined as HIV-1 RNA viral load and CD4 cell count tests occurring within one week of each other) at VHA facilities from October 1, 2006, to September 30, 2008. Patients were ≥18 years old and continuous VHA users for at least 24 months after entry into expert care. Retention measures included: Annual Appointments (≥2 appointments annually at least 60 days apart), Missed Appointments (missed ≥25% of appointments), Infrequent Appointments (>6 months without an appointment), and Missed or Infrequent Appointments (missed ≥25% of appointments or >6 months without an appointment). Multivariable nominal logistic regression models were used to determine associations between retention measures and outcomes. Overall, 8,845 patients met study criteria. At baseline, 64% of patients were virologically suppressed and 37% had a CD4 cell count >500 cells/mm3. At 24 months, 82% were virologically suppressed and 46% had a CD4 cell count >500 cells/mm3. During follow-up, 13% progressed to AIDS, 48% visited the emergency department (ED), 28% were hospitalized, and 0.3% died. All four retention measures were associated with virologic suppression and antiretroviral therapy initiation at 24 months follow-up. Annual Appointments correlated positively with CD4 cell count >500 cells/mm3. Missed Appointments was predictive of all primary and secondary outcomes, including CD4 cell count ≤500 cells/mm3, progression to AIDS, ED visit, and hospitalization. Missed Appointments was the only measure to predict all primary and secondary outcomes. This finding could be useful to health care providers and public health organizations as they seek ways to optimize the health of HIV patients.
Reactive Programming for Interactive Graphics
Creators: name: Xie, Yihui
name: Hofmann, Heike
name: Cheng, Xiaoyue
Publisher: name: arXiv
Year: 2014
Subjects: subject: Graphics (cs.GR)
subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: One of the big challenges of developing interactive statistical applications is the management of the data pipeline, which controls transformations from data to plot. The user's interactions needs to be propagated through these modules and reflected in the output representation at a fast pace. Each individual module may be easy to develop and manage, but the dependency structure can be quite challenging. The MVC (Model/View/Controller) pattern is an attempt to solve the problem by separating the user's interaction from the representation of the data. In this paper we discuss the paradigm of reactive programming in the framework of the MVC architecture and show its applicability to interactive graphics. Under this paradigm, developers benefit from the separation of user interaction from the graphical representation, which makes it easier for users and developers to extend interactive applications. We show the central role of reactive data objects in an interactive graphics system, implemented as the R package cranvas, which is freely available on GitHub and the main developers include the authors of this paper.
description: Published in at http://dx.doi.org/10.1214/14-STS477 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
ANALYSIS OF SELECTED CONTEMPORARY THREATS TO GAS INFRASTRUCTURE
Creators: name: Pilarski, Grzegorz
name: Michalik, Jacek
name: Wyszyński, Marcin
Publisher: name: Wiedza Obronna
Year: 2023

description: Nowadays, companies are increasingly using a risk-based approach to achieving their business goals. A key element of this approach is the identification of threats that may materialize and affect the functioning of the company. Following the example of the gas sector, with the gas infrastructure as the subject of research, the authors presented selected contemporary gas network threats that may occur within the mentioned sector.
description: Wiedza Obronna, Tom 283 Nr 2 (2023)
Additional file 1 of Increased chest CT derived bone and muscle measures capture markers of improved morbidity and mortality in COPD
Creators: name: Wilson, Ava C.
name: Bon, Jessica M.
name: Mason, Stephanie
name: Diaz, Alejandro A.
name: Lutz, Sharon M.
name: Estepar, Raul San Jose
name: Kinney, Gregory L.
name: Hokanson, John E.
name: Rennard, Stephen I.
name: Casaburi, Richard
name: Bhatt, Surya P.
name: Irvin, Marguerite R.
name: Hersh, Craig P.
name: Dransfield, Mark T.
name: Washko, George R.
name: Regan, Elizabeth A.
name: McDonald, Merry-Lynn
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Figure S1. Sex-stratified Clinical and Functional Measures in (A) Females and (B) Males with handgrip strengthdata. Values in red correspond to mean handgrip strength. * Corresponds to a statistically significant (p< 0.05)difference between participants with COPD and smoking controls.
The association between the selection and effectiveness of emotion regulation strategies and psychopathological features: A daily life study
Creators: name: Kalokerinos, Elise
name: Kuppens, Peter
name: Houben, Marlies
name: Erbas, Yasemin
name: Koval, Peter
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Clinical Psychology
subject: Social and Behavioral Sciences
subject: Psychology
subject: FOS: Psychology
subject: borderline personality disorder
subject: depression
subject: emotion regulation
subject: experience sampling

description: Emotion dysregulation is central to psychopathological conditions, including borderline personality disorder (BPD) and depression. However, the nature of emotion regulation (ER) difficulties in the daily life of people with BPD or depressive features is still unclear. Therefore, this study aimed to disentangle two different ER subprocesses in daily life: (1) selection of ER strategies, and (2) the effectiveness of implementing strategies, in terms of their associations with subsequent emotional experience. We analyzed data from a 3-wave longitudinal experience sampling study of young adults with varying levels of psychopathology symptoms (N=202). BPD symptomatology was uniquely linked to the use, but not altered effectiveness of several putatively adaptive and maladaptive ER strategies. Depressive features were uniquely associated with the use of putatively maladaptive strategies. These findings suggest that ER deficits in people with more BPD or depressive features may be primarily located in strategy selection, rather than the implementation of those strategies.