cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Locally detecting UV cutoffs on a sphere with particle detectors
Creators: name: Shalabi, Ahmed
name: Henderson, Laura J.
name: Mann, Robert B.
Publisher: name: arXiv
Year: 2022
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The potential breakdown of the notion of a metric at high energy scales could imply the existence of a fundamental minimal length scale below which distances cannot be resolved. One approach to realizing this minimum length scale is construct a quantum field theory with a bandlimit on the field. We report on an investigation of the effects of imposing a bandlimit on a field on a curved and compact spacetime and how best to detect such a bandlimit if it exists. To achieve this operationally, we couple two Gaussian-smeared UDW detectors to a scalar field on a $S^2 \times R$ spherical spacetime through delta-switching. The bandlimit is implemented through a cut-off of the allowable angular momentum modes of the field. We observe that a number of features of single detector response in the spherical case are similar to those in flat spacetime, including the dependence on the geometry of the detector, and that smaller detectors couple more strongly to the field, leading to an optimal size for bandlimit detection. We find that in flat spacetime squeezed detectors are more senstive to the bandlimit provided they are larger than the optimal size; however, in spherical spacetime the bandlimit itself determines if squeezing improves the sensitivity. We also explore setups with two detectors, noting that in the spherical case, due to its compact nature, there is a lack of dissipation of any perturbation to the field, which results in locally excited signals being refocused at the poles. Quite strikingly, this feature can be exploited to significantly improve bandlimit detection via field mediated signalling. Moreover, we find that squeezing on a sphere introduces extra anisotropies that could be exploited to amplify or weaken the response of the second detector.
description: 25 pages, 12 figures, 4 appendices
Старая философия и новая реальность
Creators: name: Пекелис Михаил Абрамович
name: Антипов Сергей Сергеевич
Publisher: name: Философская школа
Year: 2017
Subjects: ФИЛОСОФИЯ
ФИЛОСОФСКОЕ ТВОРЧЕСТВО
НАУКА
ИНТЕРНЕТ
АЛФИЛОСОФИЯ
НЕРЕАЛЬНАЯ РЕАЛЬНОСТЬ
АБСОЛЮТ
ФИЛОСОФСКАЯ АНТРОПОЛОГИЯ
ФИЛОСОФИЯ БУДУЩЕГО
ФУТУРОЛОГИЯ
PHILOSOPHY
PHILOSOPHICAL CREATIVITY
SCIENCE
INTERNET
ALPHILOSOPHY
UNREAL REALITY
ABSOLUTE
PHILOSOPHICAL ANTHROPOLOGY
FUTURE PHILOSOPHY
FUTUROLOGY

description: В статье рассматривается особый вид творчества философское творчество, выделяются его специфические особенности. Одна из особенностей философского творчества заключается в том, что оно, используя научный аппарат в качестве инструмента, всё же носит глубоко субъективный характер. Другая особенность философского творчества состоит в том, что почти каждая новая философская система декларирует с одной стороны свою полноту и завершенность, с претензией на окончательное, бесповоротное и исключительное объяснение всего сущего, а с другой стороны явную несостоятельность всех предшествующих философских систем. Рассматриваются «старые» и «новые» философские концепции, могущие определить будущее развитие философской мысли. В своих новых изысканиях философия проблематизирует то, что до её вмешательства казалось непроблемным, завершенным и законченным. Причём, различные направления философской мысли по разному видят будущее философии. Автор утверждает, что в будущем человека ждёт так называемая «нереальная реальность». Ростки будущего, посеянные в прошлом, прорастают через настоящее. Ставится задача развития такого важного направления философской мысли, как футурология самой философии.Review. The article describes the special type of creativity that is philosophical creativity and its specific features. One of features of philosophical creativity is that it uses the scientific device as a tool and nevertheless has deeply subjective character. Other feature is that almost each new philosophical system declares on the one hand the completeness and completeness, with a claim for a final, irrevocable and exclusive explanation of all real, and on the other hand obvious insolvency of all previous philosophical systems. There are considered "old" and "new" philosophical concepts which are able to define future development of philosophical mind. In the new researches the philosophy considers problems which seem completed and finished before its intervention. Various directions of philosophical mind differently see the future of philosophy. The author claims that in the future the person is waited by "unreal reality". The future sprouts seeded in the past sprout in the present. The task of development of such important direction of philosophical mind as futurology of the philosophy is set.
Reentrance of Berezinskii-Kosterlitz-Thouless-like transitions in three-state Potts antiferromagnetic thin film
Creators: name: Ding, Chengxiang
name: Guo, Wenan
name: Deng, Youjin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Using Monte Carlo simulations and finite-size scaling, we study three-state Potts antiferromagnet on layered square lattice with two and four layers $L_z=2$ and $4$. As temperature decreases, the system develops quasi-long-range order via a Berezinskii-Kosterlitz-Thouless transition at finite temperature $T_{c1}$. For $L_z=4$, as temperature is further lowered, a long-range order breaking the $Z_6$ symmetry develops at a second transition at $T_{c2} < T_{c1}$. The transition at $T_{c2}$ is also Berezinskii-Kosterlitz-Thouless-like, but has magnetic critical exponent $η=1/9$ instead of the conventional value $η= 1/4$. The emergent $U(1)$ symmetry is clearly demonstrated in the quasi-long-range ordered region $T_{c2} \leq T \leq T_{c1}$.
description: 6 pages, 10 figs, accepted by Phys. Rev. B
From starburst to quenching: merger-driven evolution of the star formation regimes in a shell galaxy
Creators: name: Petersson, Jonathan
name: Renaud, Florent
name: Agertz, Oscar
name: Dekel, Avishai
name: Duc, Pierre-Alain
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Shell galaxies make a class of tidally distorted galaxies, characterised by wide concentric arc(s), extending out to large galactocentric distances with sharp outer edges. Recent observations of young massive star clusters in the prominent outer shell of NGC 474 suggest that such systems host extreme conditions of star formation. In this paper, we present a hydrodynamic simulation of a galaxy merger and its transformation into a shell galaxy. We analyse how the star formation activity evolves with time, location-wise within the system, and what are the physical conditions for star formation. During the interaction, an excess of dense gas appears, triggering a starburst, i.e. an enhanced star formation rate and a reduced depletion time. Star formation coincides with regions of high molecular gas fraction, such as the galactic nucleus, spiral arms, and occasionally the tidal debris during the early stages of the merger. Tidal interactions scatter stars into a stellar spheroid, while the gas cools down and reforms a disc. The morphological transformation after coalescence stabilises the gas and thus quenches star formation, without the need for feedback from an active galactic nucleus. This evolution shows similarities with a compaction scenario for compact quenched spheroids at high-redshift, yet without a long red nugget phase. Shells appear after coalescence, during the quenched phase, implying that they do not host the conditions necessary for in situ star formation. The results suggest that shell-forming mergers might be part of the process of turning blue late-type galaxies into red and dead early-types.
description: Accepted for publication by MNRAS, 13 pages
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
Creators: name: Dickey, Chad A.
name: Kamal, Adeela
name: Dickson, Dennis W.
name: Burrows, Francis
name: Nahman, N. Stanley
name: Klosak, Natalia
name: Patterson, Cam
name: Ash, Peter
name: Hutton, Michael
name: Petrucelli, Leonard
name: Zlatkovic, Jelena
name: Dunmore, Judith
name: Lundgren, Karen
name: Shoraka, Sareh
name: Bailey, Rachel M.
name: Eckman, Christopher B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: A primary pathologic component of Alzheimer’s disease (AD) is the formation of neurofibrillary tangles composed of hyperphosphorylated tau (p-tau). Expediting the removal of these p-tau species may be a relevant therapeutic strategy. Here we report that inhibition of Hsp90 led to decreases in p-tau levels independent of heat shock factor 1 (HSF1) activation. A critical mediator of this mechanism was carboxy terminus of Hsp70–interacting protein (CHIP), a tau ubiquitin ligase. Cochaperones were also involved in Hsp90-mediated removal of p-tau, while those of the mature Hsp90 refolding complex prevented this effect. This is the first demonstration to our knowledge that blockade of the refolding pathway promotes p-tau turnover through degradation. We also show that peripheral administration of a novel Hsp90 inhibitor promoted selective decreases in p-tau species in a mouse model of tauopathy, further suggesting a central role for the Hsp90 complex in the pathogenesis of tauopathies. When taken in the context of known high-affinity Hsp90 complexes in affected regions of the AD brain, these data implicate a central role for Hsp90 in the development of AD and other tauopathies and may provide a rationale for the development of novel Hsp90-based therapeutic strategies.
17β-Estradiol inhibits Ca2+-dependent homeostasis of airway surface liquid volume in human cystic fibrosis airway epithelia
Creators: name: Young, Steven L.
name: Clunes, Lucy A.
name: Okada, Seiko F.
name: Tarran, Robert
name: Fricks, Ingrid
name: Sun, Hengrui
name: Stackhouse, James R.
name: Coakley, Ray D.
name: Rasmussen, Julia E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Normal airways homeostatically regulate the volume of airway surface liquid (ASL) through both cAMP- and Ca2+-dependent regulation of ion and water transport. In cystic fibrosis (CF), a genetic defect causes a lack of cAMP-regulated CFTR activity, leading to diminished Cl– and water secretion from airway epithelial cells and subsequent mucus plugging, which serves as the focus for infections. Females with CF exhibit reduced survival compared with males with CF, although the mechanisms underlying this sex-related disadvantage are unknown. Despite the lack of CFTR, CF airways retain a limited capability to regulate ASL volume, as breathing-induced ATP release activates salvage purinergic pathways that raise intracellular Ca2+ concentration to stimulate an alternate pathway to Cl– secretion. We hypothesized that estrogen might affect this pathway by reducing the ability of airway epithelia to respond appropriately to nucleotides. We found that uridine triphosphate–mediated (UTP-mediated) Cl– secretion was reduced during the periovulatory estrogen maxima in both women with CF and normal, healthy women. Estrogen also inhibited Ca2+ signaling and ASL volume homeostasis in non-CF and CF airway epithelia by attenuating Ca2+ influx. This inhibition of Ca2+ signaling was prevented and even potentiated by estrogen antagonists such as tamoxifen, suggesting that antiestrogens may be beneficial in the treatment of CF lung disease because they increase Cl– secretion in the airways.
Indirect Measurements of Gas Velocities in Galaxy Clusters: Effects of Ellipticity and Cluster Dynamic State
Creators: name: Zhuravleva, Irina
name: Chen, Mandy C.
name: Churazov, Eugene
name: Schekochihin, Alexander A.
name: Zhang, Congyao
name: Nagai, Daisuke
Publisher: name: arXiv
Year: 2022
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: While awaiting direct velocity measurement of gas motions in the hot intracluster medium, we rely on indirect probes, including gas perturbations in galaxy clusters. Using a sample of $\sim 80$ clusters in different dynamic states from Omega500 cosmological simulations, we examine scaling relations between the fluctuation amplitudes of gas density, $δρ/ρ$, pressure, $δP/P$, X-ray surface brightness, Sunyaev-Zeldovich (SZ) y-parameter, and the characteristic Mach number of gas motions, $M_{\rm 1d}$. In relaxed clusters, accounting for halo ellipticities reduces $δρ/ρ$ or $δP/P$ by a factor of up to 2 within $r_{500c}$. We confirm a strong linear correlation between $δρ/ρ$ (or $δP/P$) and $M_{\rm 1d}$ in relaxed clusters, with the proportionality coefficient $η\approx 1$. For unrelaxed clusters, the correlation is less strong and has a larger $η\approx 1.3\pm 0.5$ ($1.5\pm0.5$) for $δρ/ρ$ ($δP/P$). Examination of the power-law scaling of $M_{\rm 1d}$ with $δρ/ρ$ shows that it is almost linear for relaxed clusters, while for the unrelaxed ones, it is closer to $δρ/ρ\propto M_{\rm 1d}^2$, supporting an increasing role of non-linear terms and compressive modes. In agreement with previous studies, we observe a strong correlation of $M_{\rm 1d}$ with radius. Correcting for these correlations leaves a residual scatter in $M_{\rm 1d}$ of $\sim 4 (7)$ per cent for relaxed (perturbed) clusters. Hydrostatic mass bias correlates with $M_{\rm 1d}$ as strongly as with $δρ/ρ$ in relaxed clusters. The residual scatters after correcting for derived trends is $\sim 6-7$ per cent. These predictions can be verified with existing X-ray and SZ observations of galaxy clusters combined with forthcoming velocity measurements with X-ray microcalorimeters.
description: 15 pages, 11 figures, submitted
Σχεδιασμός και ανάπτυξη ψηφιακού εκπαιδευτικού παιχνιδιού για τη διδασκαλία των ισοδύναμων κλασμάτων στο δημοτικό σχολείο
Creators: name: Ρουβάς, Γεώργιος Σπυρίδων
Publisher: name: Aristotle University of Thessaloniki
Year: 2024
Subjects: Μάθηση μέσω παιχνιδιού
Μαθηματική εκπαίδευση
Ισοδύναμα κλάσματα
Δημοτικό σχολείο
Game-based learning
Mathematics education
Equivalent fractions
Elementary school

description: Η παρούσα εργασία αφορά στον σχεδιασμό και ανάπτυξη ενός ψηφιακού εκπαιδευτικού παιχνιδιού για τη διδασκαλία των ισοδύναμων κλασμάτων και απευθύνεται σε μαθητές της Ε’ Δημοτικού. Σκοπός της εργασίας είναι να αναδείξει τις δυνατότητες της μάθησης μέσω παιχνιδιού (game-based learning) που βρίσκεται πιο κοντά στα εποικοδομιστικά μοντέλα της μάθησης που επικρατούν στην εκπαιδευτική θεώρηση, έναντι της παιχνιδοποίησης που ευθυγραμμίζεται με τα συμπεριφοριστικά μοντέλα που επιμένουν να χαρακτηρίζουν την εκπαιδευτική πράξη, σε μια εποχή όπου η ανάπτυξη ψηφιακού εκπαιδευτικού υλικού είναι πλέον δυνατή και από ανθρώπους χωρίς εξειδικευμένες προγραμματιστικές γνώσεις, μία τάση που αναμένεται να συνεχιστεί.
description: The present work concerns the development of a digital educational game on the topic of equivalent fractions for 5th grade elementary students. This effort attempts to highlight the potential of game-based learning, which is closer to the constructivist models of learning prevalent in educational theory, when compared to gamification, which is aligned with the behavioristic models that insist on characterizing educational practice, in an era where the development of digital educational material is now possible even by people without specialized programming knowledge, a trend that is expected to continue.
Synchronous Chip-to-Chip Communication with a Multi-Chip Resonator Clock Distribution Network
Creators: name: Egan, Jonathan
name: Nielsen, Max
name: Strong, Joshua
name: Talanov, Vladimir V.
name: Rudman, Ed
name: Song, Brainton
name: Herr, Quentin
name: Herr, Anna
Publisher: name: arXiv
Year: 2021
Subjects: subject: Applied Physics (physics.app-ph)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Superconducting digital circuits are a promising approach to build packaged-level integrated systems with high energy-efficiency and computational density. In such systems, performance of the data link between chips mounted on a multi-chip module (MCM) is a critical driver of performance. In this work we report a synchronous data link using Reciprocal Quantum Logic (RQL) enabled by resonant clock distribution on the chip and on the MCM carrier. The simple physical link has only four Josephson junctions and 3 fJ/bit dissipation, including a 300 W/W cooling overhead. The driver produces a signal with 35\,GHz analog bandwidth and connects to a single-ended receiver via 20 $Ω$ Nb Passive Transmission Line (PTL). To validate this link, we have designed, fabricated and tested two 32$\times$32 mm$^2$ MCMs with eight 5$\times$5 mm$^2$ chips connected serially and powered with a meander clock, and with four 10$\times$10 mm$^2$ chips powered with a 2 GHz resonant clock. The meander clock MCM validates performance of the data link components, and achieved 5.4 dB AC bias margin with no degradation relative to individual chip test. The resonator MCM validates synchronization between chips, with a measured AC bias margin up to 4.8 dB between two chips. The resonator MCM is capable of powering circuits of 4 million Josephson junctions across the four chips with a projected 10 Gbps serial data rate.
description: 8 pages, 8 figures
Advanced reversible Data Hiding With Encrypted Data
Creators: name: Sreekumar, Shilpa
name: Salam, Vincy
Publisher: name: arXiv
Year: 2014
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: The advanced RDH work focuses on both data encryption and image encryption which makes it more secure and free of errors. All previous methods embed data without encrypting the data which may subject to errors on the data extraction or image recovery. The proposed work provides a novel RDH scheme in which both data and image can be encrypted and extracted reversibly without any errors. In the proposed work, data extraction and image recovery are free of any errors. The PSNR is significantly improved in the proposed work. This advanced work also performs data hiding in videos.
description: 4 pages, 10 figures, Published with International Journal of Engineering Trends and Technology (IJETT)
Идеально-смысловой критерий гениальности
Creators: name: Чернов Сергей Васильевич
Publisher: name: Философская школа
Year: 2017
Subjects: ГЕНИАЛЬНОСТЬ
ФИЛОСОФСКО-АНТРОПОЛОГИЧЕСКИЙ ПОДХОД
КУЛЬТУРНО-ИСТОРИЧЕСКИЙ ПОДХОД
ПСИХОЛОГО-ФЕНОМЕНОЛОГИЧЕСКИЙ ПОДХОД
ОБРАЗ ЛИЧНОСТИ ГЕНИЯ
ЧЕЛОВЕЧНОСТЬ
ТВОРЧЕСКОСТЬ
СОЗИДАТЕЛЬНО-ТВОРЧЕСКИЙ УМ
СМЫСЛ БЫТИЯ ЛИЧНОСТИ
КРИТЕРИЙ ГЕНИАЛЬНОСТИ
GENIUS
PHILOSOPHICAL AND ANTHROPOLOGICAL APPROACH
CULTURAL AND HISTORICAL APPROACH
PSYCHOLOGY -PHENOMENOLOGICAL APPROACH
IMAGE OF THE IDENTITY OF THE GENIUS
HUMANITY
CREATIVITY
CREATIVE AND CREATIVE MIND
MEANING OF LIFE OF THE PERSONALITY
CRITERION OF GENIUS

description: Гениальность представлена автором как особый вид сущего, как принцип, определяющий саму сущность человека и его природу, и обеспечивающий творческое многообразие смысла бытия личности. Интеграция философско-антропологического, культурно-исторического и психолого-феноменологического подходов позволяет разработать проблему гениальности в контексте фундаментальных вопросов постижения природы человека и смысла его бытия; ответить на вопросы о роли гениальности в развитии духовной культуры, как в исторической ретроспективе, так и в исторической перспективе; представить личность гения на образно-личностном, личностно-типологическом и деятельностно-смысловом уровнях. Новизна исследования заключается в разработке и обосновании идеально-смыслового критерия гениальности, основанного на трёх универсальных триадах: любовь истина красота; благое возвышенное прекрасное; человечность идеал совершенства созидательно-творческий ум.Review. Genius is presented by the author as a special kind of reality, as a principle that defines essence of a person and his nature and provides creative variety of meaning of life of the personality. Integration of philosophical and anthropological, cultural and historical and psychology-phenomenological approaches allows to develop a genius problem in the context of fundamental questions of comprehension of human nature and meaning of his life; to answer questions of a genius role in development of spiritual culture, both in a historical retrospective, and in historical perspective; to present the identity of the genius at the figurative and personal, personal and typological and activity and semantic levels. Novelty of a research consists in development and justification of the ideal and semantic criterion of genius based on three universal triads: love truth beauty; good ennobled fine; humanity -perfection ideal creative and creative mind.
Caught in the Act: A Metal-Rich High-Velocity Cloud in the Inner Galaxy
Creators: name: Cashman, Frances H.
name: Fox, Andrew J.
name: Wakker, Bart P.
name: Ashley, Trisha
name: Massa, Derck
name: Jenkins, Edward B.
name: Krishnarao, Dhanesh
name: Lockman, Felix J.
name: Benjamin, Robert A.
name: Bordoloi, Rongmon
name: Kim, Tae-Sun
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We characterize the chemical and physical conditions in an outflowing high-velocity cloud in the inner Galaxy. We report a super-solar metallicity of [O/H] = $+0.36\pm0.12$ for the high-velocity cloud at $v_\mathrm{LSR}$ = 125.6 km s$^{-1}$ toward the star HD 156359 ($l$ = 328.$^{\circ}$7, $b$ = $-$14.$^{\circ}$5, $d$ = 9 kpc, $z$ = $-$2.3 kpc). Using archival observations from FUSE, HST STIS, and ESO FEROS we measure high-velocity absorption in H I, O I, C II, N II, Si II, Ca II, Si III, Fe III, C IV, Si IV, N V, and O VI. We measure a low H I column density of log $N$(H I) = $15.54\pm0.05$ in the HVC from multiple unsaturated H I Lyman series lines in the FUSE data. We determine a low dust depletion level in the HVC from the relative strength of silicon, iron, and calcium absorption relative to oxygen, with [Si/O]=$-0.33\pm0.14$, [Fe/O]=$-0.30\pm0.20$, and [Ca/O] =$-0.56\pm0.16$. Analysis of the high-ion absorption using collisional ionization models indicates that the hot plasma is multi-phase, with the C IV and Si IV tracing 10$^{4.9}$ K gas and N V and O VI tracing 10$^{5.4}$ K gas. The cloud's metallicity, dust content, kinematics, and close proximity to the disk are all consistent with a Galactic wind origin. As the HD 156359 line of sight probes the inner Galaxy, the HVC appears to be a young cloud caught in the act of being entrained in a multi-phase Galactic outflow and driven out into the halo.
description: Submitted to ApJ, 18 pages, 13 figures, comments welcome
Искусство невозможного
Creators: name: Пекелис Михаил Абрамович
name: Антипов Сергей Сергеевич
Publisher: name: Философская школа
Year: 2017
Subjects: "КНИГА О ГЕНИАЛЬНОСТИ"
С. В. ЧЕРНОВ
ГЕНИАЛЬНОСТЬ И МОДАЛЬНОСТЬ
ГЕНИАЛЬНОСТЬ И ПОТЕНЦИАЛЬНОСТЬ
ГЕНИАЛЬНОСТЬ И КИНЕТИЧНОСТЬ
ГЕНИАЛЬНОСТЬ И СВЯТОСТЬ
ГЕНИАЛЬНОСТЬ И НОРМАЛЬНОСТЬ
АКСИОМАТИКА
СТАНОВЛЕНИЕ ГЕНИЯ
УЧЕНИЕ О ГЕНИАЛЬНОСТИ
"THE BOOK ABOUT GENIUS"
S. V. CHERNOV
GENIUS AND A MODALITY
GENIUS AND POTENTIALITY
GENIUS AND POTENTIAL
GENIUS AND SANCTITY
GENIUS AND NORMALITY
AXIOMATICS
FORMATION OF THE GENIUS
THE DOCTRINE ABOUT GENIUS

description: Статья посвящена анализу фундаментального исследования о гениальности, представленного в монографии профессора С. В. Чернова «Книга о гениальности», вышедшей в 2010 году. В книге развивается оригинальное представление о природе, сущности и становлении человеческого гения, рассматриваются вопросы универсальной и нравственной природы гения, соотношения таланта и гения, святости и гениальности, творческого дара и назначения гения. Исследуется проблема труда и духовного творчества гениальных людей, где творчество последних рассматривается как призвание и откровение; выделяются сущностные основания, личностные атрибуты и духовные признаки гениальных людей. Образ личности гения представлен автором в следующем образном триединстве: гений как творец, мыслитель и художник в одном лице.Review. Article is devoted to the analysis of a basic research about genius presented in the monograph of professor S. V. Chernov «The book about the genius» which left in 2010. In the book original idea of the nature, essence and formation of the human genius develops, questions of the universal and moral nature of the genius, a ratio of talent and the genius, sanctity and genius, a creative gift and appointment of the genius are considered. The problem of work and spiritual creativity of ingenious people where creativity of the last is considered as calling and a revelation is investigated; the intrinsic bases, personal attributes and spiritual signs of ingenious people are allocated. The image of the identity of the genius is presented by the author in the following figurative trinity: the genius as the creator, the thinker and the artist in one person.
Distribution of gamma-ray bursts on the t90-hardness ratio plane and their classification revisited
Creators: name: Zhang, Liang
name: Luo, Juan-Juan
name: Huang, Yong-Feng
name: Gong, Yu-Jun
name: Wu, Sheng
Publisher: name: arXiv
Year: 2022
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Using four mixed bivariate distributions (Normal distribution, Skew-Normal distribution, Student distribution, Skew-Student distribution) and bootstrap re-sampling analysis, we analyze the samples of CGRO/BATSE, Swift/BAT and Fermi/GBM gamma-ray bursts in detail on the t90-hardness ratio plane. The Bayesian information criterion is used to judge the goodness of fit for each sample, comprehensively. It is found that all the three samples show a symmetric (either normal or student) distribution. It is also found that the existence of three classes of gamma-ray bursts is preferred by the three samples, but the strength of this preference varies with the sample size: when the sample size of the data set is larger, the preference of three classes scheme becomes weaker. Therefore, the appearance of an intermediate class may be caused by a small sample size and the possibility that there are only two classes of gamma-ray bursts still cannot be expelled yet. A further bootstrap re-sampling analysis also confirms this result.
description: 10 pages, 9 figures
Adrenomedullin signaling is necessary for murine lymphatic vascular development
Creators: name: Caron, Kathleen M.
name: Dunworth, William P.
name: Li, Manyu
name: Fritz-Six, Kimberly L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The lymphatic vascular system mediates fluid homeostasis, immune defense, and tumor metastasis. Only a handful of genes are known to affect the development of the lymphatic vasculature, and even fewer represent therapeutic targets for lymphatic diseases. Adrenomedullin (AM) is a multifunctional peptide vasodilator that transduces its effects through the calcitonin receptor–like receptor (calcrl) when the receptor is associated with a receptor activity–modifying protein (RAMP2). Here we report on the involvement of these genes in lymphangiogenesis. AM-, calcrl-, or RAMP2-null mice died mid-gestation after development of interstitial lymphedema. This conserved phenotype provided in vivo evidence that these components were required for AM signaling during embryogenesis. A conditional knockout line with loss of calcrl in endothelial cells confirmed an essential role for AM signaling in vascular development. Loss of AM signaling resulted in abnormal jugular lymphatic vessels due to reduction in lymphatic endothelial cell proliferation. Furthermore, AM caused enhanced activation of ERK signaling in human lymphatic versus blood endothelial cells, likely due to induction of CALCRL gene expression by the lymphatic transcriptional regulator Prox1. Collectively, our studies identify a class of genes involved in lymphangiogenesis that represent a pharmacologically tractable system for the treatment of lymphedema or inhibition of tumor metastasis.
[Halle (Saale), Universitäts- und Landesbibliothek Sachsen-Anhalt, Morbio 6 (56)]
Creators: name: De Zanatis, Franceschina
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 1422
Subjects: subject: Sonstige weltliche Aussteller
subject: Inventar
subject: Notarsurkunde
subject: Urkunde
subject: 090

description: Franceschina de Zanatis, Tochter des verstorbenen Zaninus und Witwe des Johannes de Anselmis, seinerseits Sohn des verstorbenen Albertinus, aus der Nachbarschaft St. Mercadelli in Cremona sowie Vormund ihrer und des genannten Johannes Kinder Albertinus, Johannes und Caterina, ihrerseits Erben des Johannes, fertigt ein Inventar der Güter ihrer Mündel an.
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome
Creators: name: Mackman, Nigel
name: Girardi, Guillermina
name: Franzke, Claus-Werner
name: Redecha, Patricia
name: Ruf, Wolfram
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Women with antiphospholipid syndrome (APS), a condition characterized by the presence of antiphospholipid antibodies (aPL), often suffer pregnancy-related complications, including miscarriage. We have previously shown that C5a induction of tissue factor (TF) expression in neutrophils contributes to respiratory burst, trophoblast injury, and pregnancy loss in mice treated with aPL. Here we analyzed how TF contributes to neutrophil activation and trophoblast injury in this model. Neutrophils from aPL-treated mice expressed protease-activated receptor 2 (PAR2), and stimulation of this receptor led to neutrophil activation, trophoblast injury, and fetal death. An antibody specific for human TF that has little impact on coagulation, but potently inhibits TF/Factor VIIa (FVIIa) signaling through PAR2, inhibited aPL-induced neutrophil activation in mice that expressed human TF. Genetic deletion of the TF cytoplasmic domain, which allows interaction between TF and PAR2, reduced aPL-induced neutrophil activation in aPL-treated mice. Par2–/– mice treated with aPL exhibited reduced neutrophil activation and normal pregnancies, which indicates that PAR2 plays an important role in the pathogenesis of aPL-induced fetal injury. We also demonstrated that simvastatin and pravastatin decreased TF and PAR2 expression on neutrophils and prevented pregnancy loss. Our results suggest that TF/FVIIa/PAR2 signaling mediates neutrophil activation and fetal death in APS and that statins may be a good treatment for women with aPL-induced pregnancy complications.
Finite-size effects on the phase transition in a four- and six-fermion interaction model
Creators: name: Abreu, L. M.
name: Khanna, F. C.
name: Malbouisson, A. P. C.
name: Malbouisson, J. M. C.
name: Santana, A. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider four- and six-fermion interacting models at finite temperature and density. We construct the corresponding free energies and investigate the appearance of first- and second-order phase transitions. Finite-size effects on the phase structure are investigated using methods of quantum field theory on toroidal topologies
Few-cycle pulse generation by double-stage hybrid multi-pass multi-plate nonlinear pulse compression
Creators: name: Viotti, Anne-Lise
name: Li, Chen
name: Arisholm, Gunnar
name: Winkelmann, Lutz
name: Hartl, Ingmar
name: Heyl, Christoph M.
name: Seidel, Marcus
Publisher: name: arXiv
Year: 2022
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Few-cycle pulses present an essential tool to track ultrafast dynamics in matter and drive strong field effects. To address photon-hungry applications, high average power lasers are used which, however, cannot directly provide sub-100 fs pulse durations. Post-compression of laser pulses by spectral broadening and dispersion compensation is the most efficient method to overcome this limitation. Here, we demonstrate a notably compact setup which turns a 0.1 GW peak power, picosecond laser into a 2.9 GW peak power, 8.2 fs source. The 120-fold pulse duration shortening is accomplished in a two-stage hybrid multi-pass, multi-plate compression setup. To our knowledge, neither shorter pulses, nor higher peak powers have been reported to-date from bulk multi-pass cells alone, manifesting the power of the hybrid approach. It puts, for instance, compact, cost-efficient and high repetition rate attosecond sources within reach.
Measuring the Cosmic X-ray Background accurately
Creators: name: Li, Hancheng
name: Produit, Nicolas
name: Walter, Roland
Publisher: name: arXiv
Year: 2021
Subjects: subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Measuring the Cosmic X-ray Background (CXB) is a key to understand the Active Galactic Nuclei population, their absorption distribution and their average spectra. However, hard X-ray instruments suffer from time-dependent backgrounds and cross-calibration issues. The uncertainty of the CXB normalization remain of the order of 20%. To obtain a more accurate measurement, the Monitor Vsego Neba (MVN) instrument was built in Russia but not yet launched to the ISS (arXiv:1410.3284). We follow the same ideas to develop a CXB detector made of four collimated spectrometers with a rotating obturator on top. The collimators block off-axis photons below 100 keV and the obturator modulates on-axis photons allowing to separate the CXB from the instrumental background. Our spectrometers are made of 20 mm thick CeBr$_{3}$ crystals on top of a SiPM array. One tube features a $\sim$20 cm$^2$ effective area and more energy coverage than MVN, leading to a CXB count rate improved by a factor of $\sim$10 and a statistical uncertainty $\sim$0.5% on the CXB flux. A prototype is being built and we are seeking for a launch opportunity.
description: 8 pages, 5 figures, 37th International Cosmic Ray Conference (ICRC2021)
Intermittency and Lifetime of the 625 Hz QPO in the 2004 Hyperflare from the Magnetar SGR 1806-20 as evidence for magnetic coupling between the crust and the core
Creators: name: Huppenkothen, Daniela
name: Watts, Anna L.
name: Levin, Yuri
Publisher: name: arXiv
Year: 2014
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Quasi-periodic oscillations (QPOs) detected in the 2004 giant flare from SGR 1806-20 are often interpreted as global magneto-elastic oscillations of the neutron star. There is, however, a large discrepancy between theoretical models, which predict that the highest frequency oscillations should die out rapidly, and the observations, which suggested that the highest-frequency signals persisted for ~100s in X-ray data from two different spacecraft. This discrepancy is particularly important for the high-frequency QPO at ~625 Hz. However, previous analyses did not systematically test whether the signal could also be there in much shorter data segments, more consistent with the theoretical predictions. Here, we test for the presence of the high-frequency QPO at 625 Hz in data from both the Rossi X-ray Timing Explorer (RXTE) and the Ramaty High Energy Solar Spectroscopic Imager (RHESSI) systematically both in individual rotational cycles of the neutron star, as well as averaged over multiple successive rotational cycles at the same phase. We find that the QPO in the RXTE data is consistent with being only present in a single cycle, for a short duration of ~0.5s, whereas the RHESSI data are as consistent with a short-lived signal that appears and disappears as with a long-lived QPO. Taken together, this data provides evidence for strong magnetic interaction between the crust and the core.
description: Accepted for publication in ApJ. The data and simulations are available at http://figshare.com/articles/SGR_1806_20_Giant_Flare_Data_and_Simulations/1126082 , the code can be downloaded from https://github.com/dhuppenkothen/giantflare-paper , some documentation is under http://nbviewer.ipython.org/github/dhuppenkothen/giantflare-paper/blob/master/documents/giantflare-analysis.ipynb
Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation
Creators: name: von Brühl, Marie-Luise
name: Lorenz, Michael
name: Hess, Sonja
name: Engelmann, Bernd
name: Orschiedt, Lena
name: Konrad, Ildiko
name: Grahl, Lenka
name: Massberg, Steffen
name: Altmann, Berid
name: Ruddock, Lloyd
name: Mackman, Nigel
name: Dlugai, Silke
name: Reinhardt, Christoph
name: Manukyan, Davit
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: The activation of initiator protein tissue factor (TF) is likely to be a crucial step in the blood coagulation process, which leads to fibrin formation. The stimuli responsible for inducing TF activation are largely undefined. Here we show that the oxidoreductase protein disulfide isomerase (PDI) directly promotes TF-dependent fibrin production during thrombus formation in vivo. After endothelial denudation of mouse carotid arteries, PDI was released at the injury site from adherent platelets and disrupted vessel wall cells. Inhibition of PDI decreased TF-triggered fibrin formation in different in vivo murine models of thrombus formation, as determined by intravital fluorescence microscopy. PDI infusion increased — and, under conditions of decreased platelet adhesion, PDI inhibition reduced — fibrin generation at the injury site, indicating that PDI can directly initiate blood coagulation. In vitro, human platelet–secreted PDI contributed to the activation of cryptic TF on microvesicles (microparticles). Mass spectrometry analyses indicated that part of the extracellular cysteine 209 of TF was constitutively glutathionylated. Mixed disulfide formation contributed to maintaining TF in a state of low functionality. We propose that reduced PDI activates TF by isomerization of a mixed disulfide and a free thiol to an intramolecular disulfide. Our findings suggest that disulfide isomerases can act as injury response signals that trigger the activation of fibrin formation following vessel injury.
A mechanism of bar formation in disk galaxies: synchronization of apsidal precession
Creators: name: Bekki, Kenji
Publisher: name: arXiv
Year: 2022
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We discuss the mechanism(s) of bar formation in isolated and tidally interacting disk galaxies using the results of idealized collisionless Nbody simulations of the galaxies. In order to better understand the mechanism, we investigate orbital eccentricities (e), epochs of apocenter passages (t_a), azimuthal angles at t_a (varphi_a), precession rates (Omega_pre), for individual stars, as well as bar strengths represented by relative m=2 Fourier amplitude (A_2) and bar pattern speeds (Omega_bar). The main results are as follows. A significant fraction of stars with initially different varphi_a and Omega_pre in an isolated disk galaxy can have similar values within several dynamical timescales. This synchronization of varphi_a and Omega_pre, which is referred to as apsidal precession synchronization (``APS'') in the present study, is caused by the enhanced strength of the tangential component of gravitational force. A weak seed bar (A_2<0.1) is first formed through APS in local regions of a disk, then the bar grows due to APS. In the bar growth phase (0.1
description: 27 pages with 25 figures, accepted by MNRAS
A characterization of fast decaying solutions for quasilinear and Wolff type systems with singular coefficients
Creators: name: Villavert, John
Publisher: name: arXiv
Year: 2014
Subjects: subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics
subject: Primary: 35B40, 45G05, 45M05, Secondary: 35J92

description: This paper examines the decay properties of positive solutions for a family of fully nonlinear systems of integral equations containing Wolf potentials and Hardy weights. This class of systems includes examples which are closely related to the Euler-Lagrange equations for several classical inequalities such as the Hardy-Sobolev and Hardy-Littlewood-Sobolev inequalities. In particular, a complete characterization of the fast decaying ground states in terms of their integrability is provided in that bounded and fast decaying solutions are shown to be equivalent to the integrable solutions. In generating this characterization, additional properties for the integrable solutions, such as their boundedness and optimal integrability, are also established. Furthermore, analogous decay properties for systems of quasilinear equations of the weighted Lane-Emden type are also obtained.
description: 26 pages
Opinion Dynamics and Unifying Principles: A Global Unifying Frame
Creators: name: Galam, Serge
Publisher: name: arXiv
Year: 2022
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: I review and extend the set of unifying principles, which allow comparing all models of opinion dynamics within one single frame. Within the Global Unifying Frame (GUF), any specific update rule chosen to study opinion dynamics for discrete individual choices is recast into a probabilistic update formula. The associated dynamics is deployed using a general probabilistic sequential process, which is iterated via the repeated reshuffling of agents between successive rounds of local updates. The related driving attractors and tipping points are obtained with non-conservative regimes featuring both threshold and threshold-less dynamics. Most stationary states are symmetry broken, but fifty-fifty coexistence may also occur. A practical procedure is exhibited for several versions of Galam and Sznajd models when restricted to the use of three agents for the local updates. Comparing these various models, some are found to be identical within the GUF. Possible discrepancies with numerical simulations are discussed together with the difference between the GUF procedure and a mean field approach.
description: 26 pages, 3 figures, Contribution to Special Issue "Statistical Physics of Opinion Formation and Social Phenomena"
Optical spin-wave detection beyond the diffraction limit
Creators: name: Lucassen, J.
name: Peeters, M. J. G.
name: Schippers, C. F.
name: Duine, R. A.
name: Swagten, H. J. M.
name: Koopmans, B.
name: Lavrijsen, R.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Spin waves are proposed as information carriers for next-generation computing devices because of their low power consumption. Moreover, their wave-like nature allows for novel computing paradigms. Conventional methods to detect spin waves are based either on electrical induction, limiting the downscaling and efficiency complicating eventual implementation, or on light scattering, where the minimum detectable spin-wave wavelength is set by the wavelength of the laser. In this Article we demonstrate magneto-optical detection of spin waves beyond the diffraction limit using a metallic grating that selectively absorbs laser light. Specifically, we demonstrate the detection of propagating spin waves with a wavelength of 700 nm using a diffraction-limited laser spot with a size of 10 $μ$m in 20 nm thick Py strips. Additionally, we show that this grating is selective to the wavelength of the spin wave, providing wavevector-selective spin-wave detection. This should open up new avenues towards the integration of the burgeoning fields of photonics and magnonics, and aid in the optical detection of spin waves in the short-wavelength exchange regime for fundamental research.
description: Includes supplementary
Pseudo-harmonic Hermitian structures on Weyl manifolds
Creators: name: Shakoor, Kamran
name: Davidov, Johann
Publisher: name: arXiv
Year: 2022
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 53C43, 58E20

description: We find geometric conditions on a Hermitian-Weyl manifold under which the complex structure is a pseudo-harmonic map in the sense of G. Kokarev \cite{K09} from the manifold into its twistor space. This is done under the assumption that the dimension of the manifold is four or the Hermitian-Weyl structure is locally conformally Kähler.
A new regime of nanoscale thermal transport: collective diffusion counteracts dissipation inefficiency
Creators: name: Hoogeboom-Pot, Kathleen M.
name: Hernandez-Charpak, Jorge N.
name: Anderson, Erik H.
name: Gu, Xiaokun
name: Yang, Ronggui
name: Murnane, Margaret M.
name: Kapteyn, Henry C.
name: Nardi, Damiano
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Understanding thermal transport from nanoscale heat sources is important for a fundamental description of energy flow in materials, as well as for many technological applications including thermal management in nanoelectronics, thermoelectric devices, nano-enhanced photovoltaics and nanoparticle-mediated thermal therapies. Thermal transport at the nanoscale is fundamentally different from that at the macroscale and is determined by the distribution of carrier mean free paths in a material, the length scales of the heat sources, and the distance over which heat is transported. Past work has shown that Fourier's law for heat conduction dramatically over-predicts the rate of heat dissipation from heat sources with dimensions smaller than the mean free path of the dominant heat-carrying phonons. In this work, we uncover a new regime of nanoscale thermal transport that dominates when the separation between nanoscale heat sources is small compared with the dominant phonon mean free paths. Surprisingly, the interplay between neighboring heat sources can facilitate efficient, diffusive-like heat dissipation, even from the smallest nanoscale heat sources. This finding suggests that thermal management in nanoscale systems including integrated circuits might not be as challenging as projected. Finally, we demonstrate a unique and new capability to extract mean free path distributions of phonons in materials, allowing the first experimental validation of differential conductivity predictions from first-principles calculations.
description: Main text: 18 pages, 4 figures. Supplementary Information: 13 pages, 9 figures