cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Modelling of oscillations in two-dimensional echo-spectra of the Fenna–Matthews–Olson complex
Creators: name: Hein, Birgit
name: Kreisbeck, Christoph
name: Kramer, Tobias
name: Rodríguez, Mirta
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: Biological physics
subject: 530 Physik
subject: 87.14.E
subject: 87.15.M
subject: 87.15.A

description: Recent experimental observations of time-dependent beatings in the two-dimensional echo-spectra of light-harvesting complexes at ambient temperatures have opened up the question of whether coherence and wave-like behaviour play a significant role in photosynthesis. We carry out a numerical study of the absorption and echo-spectra of the Fenna–Matthews–Olson (FMO) complex in Chlorobium tepidum and analyse the requirements in the theoretical model needed to reproduce beatings in the calculated spectra. The energy transfer in the FMO pigment–protein complex is theoretically described by an exciton Hamiltonian coupled to a phonon bath which accounts for the pigments' electronic and vibrational excitations, respectively. We use the hierarchical equations of motions method to treat the strong couplings in a non-perturbative way. We show that the oscillations in the two-dimensional echo-spectra persist in the presence of thermal noise and static disorder.
АЛЬБЕР КАМЮ: ВОЗМОЖНА ЛИ МОРАЛЬ В СИТУАЦИИ АБСУРДА?
Creators: name: КОРТУНОВ ВАДИМ ВАДИМОВИЧ
name: МАМЕДОВ АЗЕР АГАБАЛА ОГЛЫ
name: КОТУСОВ ДМИТРИЙ ВЯЧЕСЛАВОВИЧ
Publisher: name: Сервис plus
Year: 2019
Subjects: АБСУРД
КАМЮ
СВОБОДА
ЭКЗИСТЕНЦИАЛИЗМ
ЭТИКА
ABSURD
CAMUS
FREEDOM
EXISTENTIALISM
ETHICS

description: В работе ставится вопрос об этическом наследии экзистенциальной философии в лице А. Камю. Демонстрируется, что на базе абсурдистской философии, отрицающей существование высшего смысла, возможна аргументация против моральной вседозволенности. Авторы показывают, что чувство абсурда приводит нас к бунту во имя защиты достоинства человеческой личности. Если мир в лице природы или социума попирает это достоинство, утверждая никчемность и ненужность человеческой жизни, бунтарь будет бороться за создание общества, исходящего из прямо противоположного.
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
Creators: name: Kakizuka, A.
name: Miller Jr., W. H.
name: Umesono, K.
name: Warrell Jr., R. P.
name: Frankel, Stanley R.
name: Vundavalli, Murty V.
name: Dmitrovsky, E.
name: Evans, R. M.
Publisher: name: Columbia University
Year: 1991
Subjects: DNA-protein interactions
Myeloid leukemia
Leukemia
Biochemistry

description: A unique mRNA produced in leukemic cells from a t(15;17) acute promyelocytic leukemia (APL) patient encodes a fusion protein between the retinoic acid receptor a (RARa) and a myeloid gene product called PML. PML contains a cysteine-rich region present in a new family of apparent DNA-binding proteins that includes a regulator of the interleukin-2 receptor gene (Rpt-1) and the recombination-activating gene product (RAG-l). Accordingly, PML may represent a novel transcription factor or recombinase. The aberrant PML-RAR fusion product, while typically retinoic acid responsive, displays both cell type- and promoter-specific differences from the wild-type RARa. Because patients with APL can be Induced into remission with high dose RA therapy, we propose that the nonliganded PML-RAR protein is a new class of dominant negative oncogene product. Treatment with RA would not only relieve this inhibition, but the activated PML-RAR protein may actually promote myelocyte differentiation.
On macroscopic dimension of rationally essential manifolds
Creators: name: Dranishnikov, Alexander
Publisher: name: arXiv
Year: 2010
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics

description: We construct a counterexamples in dimensions $n>3$ to Gromov's conjecture \cite{Gr1} that the macroscopic dimension of rationally essential $n$-dimensional manifolds equals $n$.
Monte Carlo simulations to replace film dosimetry in IMRT verification
Creators: name: Goetzfried, Thomas
name: Rickhey, Mark
name: Treutwein, Marius
name: Koelbl, Oliver
name: Bogner, Ludwig
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: IMRT;Monte Carlo simulation;Film dosimetry;QA;Monte-Carlo-Simulation;Filmdosimetrie;Qualitätssicherung
subject: 530 Physik
subject: 610 Medizin

description: Patient-specific verification of intensity-modulated radiation therapy (IMRT) plans can be done by dosimetric measurements or by independent dose or monitor unit calculations. The aim of this study was the clinical evaluation of IMRT verification based on a fast Monte Carlo (MC) program with regard to possible benefits compared to commonly used film dosimetry. 25 head-and-neck IMRT plans were recalculated by a pencil beam based treatment planning system (TPS) using an appropriate quality assurance (QA) phantom. All plans were verified both by film and diode dosimetry and compared to MC simulations. The irradiated films, the results of diode measurements and the computed dose distributions were evaluated, and the data were compared on the basis of gamma maps and dose-difference histograms. Average deviations in the high-dose region between diode measurements and point dose calculations performed with the TPS and MC program were 0.7 ± 2.7% and 1.2 ± 3.1%, respectively. For film measurements, the mean gamma values with 3% dose difference and 3mm distance-to-agreement were 0.74 ± 0.28 (TPS as reference) with dose deviations up to 10%. Corresponding values were significantly reduced to 0.34 ± 0.09 for MC dose calculation. The total time needed for both verification procedures is comparable, however, by far less labor intensive in the case of MC simulations. The presented study showed that independent dose calculation verification of IMRT plans with a fast MC program has the potential to eclipse film dosimetry more and more in the near future. Thus, the linac-specific QA part will necessarily become more important. In combination with MC simulations and due to the simple set-up, point-dose measurements for dosimetric plausibility checks are recommended at least in the IMRT introduction phase.
description: NOTICE: this is the author’s version of a work that was accepted for publication in . Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Zeitschrift für Medizinische Physik, VOL 21, ISSUE 1, 2011, DOI 10.1016/j.zemedi.2010.05.002
The Effects of Viewing Visual Artwork in Healthcare Settings: A Scoping Review
Creators: name: Foster, Marcel W.
name: Sajnani, Nisha
name: Morgan-Daniel, Jane
Publisher: name: OSF Registries
Year: 2024
Subjects: subject: Medicine and Health Sciences
subject: Life Sciences
subject: Arts and Humanities
subject: Social and Behavioral Sciences
subject: art viewing; healthcare; hospitals; visual art; wellbeing; wellness; belonging

description: The objective of this scoping review is to more fully comprehend the evidence related to the effects of wellbeing, wellness, and belonging when participants view visual artwork in healthcare settings.
Afrocentric education : what does it mean to Toronto’s black parents?
Creators: name: Radebe, Patrick
Publisher: name: University of British Columbia
Year: 2017

description: The miseducation of Black students attending Toronto metropolitan secondary schools, as evinced by poor grades and high dropout rates among the highest in Canada, begs the question of whether responsibility for this phenomenon lies with a public school system informed by a Eurocentric ethos. Drawing on Afrocentric Theory, this critical qualitative study examines Black parents’ perceptions of the Toronto Africentric Alternative School and Afrocentric education. Snowball sampling and ethnographic interviews, i.e., semi-structured interviews, were used to generate data. A total of 12 Black parents, three men and nine women, were interviewed over a 5-month period and data analyzed. It was found that while a majority of the respondents supported the Toronto Africentric Alternative School and Afrocentric education, some were ambivalent and others viewed the school and the education it provides as divisive and unnecessary. The research findings show that the majority of the participants were enamored with Afrocentricity, believing it to be a positive influence on Black lives. While they supported TAAS and AE, the minority, on the other hand, opposed the school and its educational model. The findings also revealed a Black community, divided between a majority seeking to preserve whatever remained of (their) African identity and a determined minority that viewed assimilation to be in the best interests of Black students. It is recommended that the school adopt antiracist education; that it appoints a spokesperson to field public inquiries to counter adverse perceptions of the school and its programs; that it fosters an on-going dialogue between its supporters and critics; and, most importantly, that it takes steps aimed at rebuilding relations among the stakeholders, i.e., the school, Black parents, the Toronto District School Board and the community.
Extracellular matrix-modulated expression of human cell surface glycoproteins A42 and J143. Intrinsic and extrinsic signals determine antigenic phenotype.
Creators: name: Rettig, W. J.
name: Vundavalli, Murty V.
name: Mattes, M. J.
name: Chaganti, R. S.
name: Old, L. J.
Publisher: name: Columbia University
Year: 1986
Subjects: Phenotypic plasticity
Cell receptors
Extracellular matrix
Biochemistry

description: Extracellular matrix (ECM)' plays an important regulatory role in cellular
growth, migration, and differentiation (1-4). Pathologic processes such as tumor
cell invasion and metastasis are also determined by cellular interactions with
ECM (5, 6). Biochemical studies have identified collagens, fibronectin, laminin,
proteoglycans, and several other proteins as major ECM components (1-3), and
have shown that ECM composition varies between different normal and tumor
tissues. The complexity and heterogeneity of ECM composition have hampered
the molecular analysis of ECM-cell interactions . However, a range of phenotypic
changes has been described for cultured cells after transfer from plastic surfaces
to substrates coated with native ECM (7, 8) or with purified ECM components;
ECM-induced phenotypic changes include enhanced substrate adhesiveness, cell
spreading and migration, changes in cell morphology and proliferative activity,
and expression of differentiated cellular functions (I-4). Some of these effects,
e.g., increased substrate adhesion, may result directly from the binding of
specialized cell surface structures to ECM molecules. Others are likely mediated
by an active cellular response triggered by the interaction of ECM with cell
surface receptors. Thus, ECM-derived signals (9) may activate a cascade of
molecular changes within the cell and on the cell surface that account for the
pleiotropic effects observed with ECM.
О НЕКОТОРЫХ ПРОБЛЕМАХ ЭТИКИ И ПЕДАГОГИКИ ПРИ РАБОТЕ С ПРЕУСПЕВАЮЩИМИ СТУДЕНТАМИ
Creators: name: ЛАПШИН ИВАН ЕВГЕНЬЕВИЧ
Publisher: name: Сервис plus
Year: 2019
Subjects: ЭТИКА
ПЕДАГОГИКА
ОЦЕНКА РАБОТЫ СТУДЕНТОВ
ETHICS
PEDAGOGY
ASSESSMENT OF STUDENTS

description: Статья посвящена анализу этико-педагогических проблем, возникающих перед преподавателем при оценивании ответа студента на экзамене или семинаре и связанных с неоднородностью студенческих групп в плане успеваемости. Рассматриваемые в статье проблемы трудно назвать новыми, тем не менее, в силу ряда причин именно в начале XXI века вопрос справедливости при оценке результатов работы студентов стоит чрезвычайно остро. С течением времени эта сторона работы преподавателя не упрощается, а, наоборот, сталкивается со все новыми и новыми сложностями. Возросшая степень стандартизации образования едва ли помогает систематизировать работу преподавателя в этом плане. Данная статья рассматривает ряд дилемм, с которыми сталкивается преподаватель в своей повседневной работе, а также предлагает некоторые направления мысли, которые могут привести если не к конкретным выводам относительно справедливости или несправедливости некоторых решений, то, по крайней мере, к большей ясности при принятии непростых решений.
ИДЕЯ БОЖЕСТВЕННОГО В ФИЛОСОФИИ НИГИЛИЗМА Ф. НИЦШЕ В ВОСПРИЯТИИ В.С. СОЛОВЬЕВА, А. БЕЛОГО, Л. ШЕСТОВА И А.Ф. ЛОСЕВА
Creators: name: КОСОРУКОВА АЛЕКСАНДРА АНДРЕЕВНА
Publisher: name: Сервис plus
Year: 2019
Subjects: PHILOSOPHY OF NIHILISM
F. NIETZSCHE
V. S. SOLOVYOV
A. BELY
L. SHESTOV
A. F. LOSEV
"DEATH OF GOD"
APOLLONIAN
DIONYSIAN
ФИЛОСОФИЯ НИГИЛИЗМА
Ф. НИЦШЕ
В.С. СОЛОВЬЕВ
А. БЕЛЫЙ
Л. ШЕСТОВ
А.Ф. ЛОСЕВ
«СМЕРТЬ БОГА»
АПОЛЛОНИЧЕСКОЕ
ДИОНИСИЙСКОЕ

description: Целью статьи является рассмотрение контекста вопроса о Боге и идее божественного в философии Ф. Ницше, что предпринимается на основе анализа восприятия данного вопроса в русской религиозной философии конца 19 первой трети 20 веков. А именно теоретическими источниками исследования заявленного вопроса у Ницше служат работы крупнейших авторов по данной теме в русской религиозной философии данного периода В.С. Соловьева, А. Белого, Л. Шестова и А.Ф. Лосева. Ключевой гипотезой статьи является мысль о том, что общим контекстом понимания мысли Ницше о Боге является его философия нигилизма, которая включает в себя целую палитру вопросов от провозглашения тезиса «Бог умер» до поисков причин утраты веры и виновных в смерти Бога. В работе использовались историко-философский и общенаучные методы, а также интерпретация методологии Ницше через созданный им метод понимания культуры дихотомию аполлонического и дионисийского принципов мышления. Автором предлагается собственная классификация воззрений указанных отечественных прочтений идеи божественного у Ницше. Основой классификацией служит принадлежность прочтения Ницше к одному из полюсов: Ницше как максимально или минимально «дионисийский» мыслитель, а также Ницше как максимально или минимально «аполлонический» мыслитель (то есть в своей же собственной методологии проявляющий открытые им же принципы). Данный результат может иметь широкое применение как в дидактических целях, так и при решении задач по анализу применимости ницшеанских концептов и ходов мысли к проблемам религиозной этики.
Perinatal Health Among 1 Million American-Born Chinese
Creators: name: Almond, Douglas V.
name: Cheng, Yi
Publisher: name: Columbia University
Year: 2016
Subjects: Chinese Americans
Maternal health services
Sex of children, Parental preferences for
Economics

description: Son preference is well documented in many Asian counties. Sex selection generates sex ratios (# of males/# of females) above the biologically normal ratio of around 1.05 at birth. For China, Chen, Li, and Meng [2013] argue that availability of prenatal sex determination through ultrasound lead to a 40-50% increase in the sex imbalance during the 1980s. Son preference manifests in sibling sex composition, where the sex ratio of firstborn children is relatively normal but rises at higher birth orders in the absence of a previous son [Yi et al., 1993]. Because official birth certificate and hospital discharge microdata are not publicly available for China, most studies analyze population census data. This tends to focus empirical work on the sex imbalance itself. A key unanswered question is the effect of gender preference on “survivors”. An exception is Li and Wu [2011], who use the China Health and Nutrition Survey to show that mother’s nutrition may deteriorate postpartum upon having a daughter relative to a son.
Gender preference aside, perinatal health has a profound impact on population health. The WHO defines the perinatal period as running from 22 weeks gestation to 7 days after birth. Over half of infant deaths occur within first 7 days of life. The death rate for children under age one is more than 13 times higher than the death rate for children age 15 to 19, the group with the next highest rate. Moreover, the fetal origins hypothesis suggests that small gaps in perinatal health can map to large later-life gaps. In the absence of data for China, we explore the perinatal health of American-born Chinese (1.2% of US population).
Identification of H$_2$CCC as a diffuse interstellar band carrier
Creators: name: Maier, J. P.
name: Walker, G. A. H.
name: Bohlender, D. A.
name: Mazzotti, F. J.
name: Raghunandan, R.
name: Fulara, J.
name: Garkusha, I.
name: Nagy, A.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present strong evidence that the broad, diffuse interstellar bands (DIBs) at 4881 and 5450\,Åare caused by the $B\,^1$B$_1$\,$\leftarrow$\,$X\,^1$A$_1$ transition of H$_2$CCC (l-C$_3$H$_2$). The large widths of the bands are due to the short lifetime of the $B\,^1$B$_1$ electronic state. The bands are predicted from absorption measurements in a neon matrix and observed by cavity ring-down in the gas phase and show exact matches to the profiles and wavelengths of the two broad DIBs. The strength of the 5450\,ÅDIB leads to a l-C$_3$H$_2$ column density of $\sim5\times10^{14}$ cm$^{-2}$ towards HD\,183143 and $\sim2\times10^{14}$\,cm$^{-2}$ to HD\,206267. Despite similar values of $E$($B-V$), the 4881 and 5450\,ÅDIBs in HD\,204827 are less than one third their strength in HD\,183143, while the column density of interstellar C$_3$ is unusually high for HD\,204827 but undetectable for HD\,183143. This can be understood if C$_3$ has been depleted by hydrogenation to species such as l-C$_3$H$_2$ towards HD\,183143. There are also three rotationally resolved sets of triplets of l-C$_3$H$_2$ in the 6150$-$6330\,Åregion. Simulations, based on the derived spectroscopic constants and convolved with the expected instrumental and interstellar line broadening, show credible coincidences with sharp, weak DIBs for the two observable sets of triplets. The region of the third set is too obscured by the $α$-band of telluric O$_2$.
description: 22 pages, 9 figures
Borrowing Abroad: The Debtor's Perspective
Creators: name: Cooper, Richard N.
name: Sachs, Jeffrey D.
Publisher: name: Columbia University
Year: 1984
Subjects: Managerial economics

description: This paper addresses the question of external borrowing from the perspective of the borrowing country. The first section sketches a formal framework for optimal borrowing by a developing country, as seen from the planner's point of view. The next three sections use this framework for the development of three important limits on external borrowing: the problem of solvency, the problem of liquidity and the problem created by the possibility of repudiation. The fifth section relates external borrowing to macroeconomic management of the borrowing country, and the sixth section pulls together the many factors that suggest that external debt of a country should be subject to central management or at least surveillance. Following that, we offer some guidelines for limits to the magnitude of external debt, and then discuss the character or mix of external debt. In an appendix, we present various simulation exercises for optimal debt management in a discrete-time infinite-horizon setting.
СПОРТИВНАЯ ДУХОВНОСТЬ КАК ПРЕДМЕТ ТЕОЛОГО-ФИЛОСОФСКОГО РАССМОТРЕНИЯ
Creators: name: БИРЮКОВ ИГОРЬ ЛЕОНИДОВИЧ
Publisher: name: Сервис plus
Year: 2019
Subjects: ДУХОВНОСТЬ
СПОРТИВНАЯ ДЕЯТЕЛЬНОСТЬ
СПОРТИВНАЯ ДУХОВНОСТЬ
САКРАЛИЗАЦИЯ
ПОСТМОДЕРН
РЕЛИГИОЗНЫЕ ВЕРОВАНИЯ
СПОРТ
АГОН
МИРОВОЗЗРЕНИЕ
SPIRITUALITY
SPORTS ACTIVITY
SPORTS SPIRITUALITY
SACRALISATION
POSTMODERNISM
RELIGIOUS BELIEFS
SPORT
AGON
WORLDVIEW

description: В статье автор систематизирует ранее обозначенную проблематику вопрос духовности в спортивной и физкультурной деятельности. Рассматривает роль религиозной веры в физической культуре, применяет философские обоснования данного явления. Также автор определяет понятие спортивной духовности, выводит его объем и содержание, анализирует компонент сакральности и его влияния на процессы личностного и общественного становления. В конце статьи делаются выводы о спортивной духовности как полноценной области научного знания своим понятийным аппаратом, предметом, объектом и методологией исследования.
How to be causal: time, spacetime, and spectra
Creators: name: Kinsler, Paul
Publisher: name: arXiv
Year: 2011
Subjects: subject: Classical Physics (physics.class-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: I explain a simple definition of causality in widespread use, and indicate how it links to the Kramers Kronig relations. The specification of causality in terms of temporal differential eqations then shows us the way to write down dynamical models so that their causal nature /in the sense used here/ should be obvious to all. To extend existing treatments of causality that work only in the frequency domain, I derive a reformulation of the long-standing Kramers Kronig relations applicable not only to just temporal causality, but also to spacetime "light-cone" causality based on signals carried by waves. I also apply this causal reasoning to Maxwell's equations, which is an instructive example since their casual properties are sometimes debated.
description: v4 - add Appdx A, "discrete" picture (not in EJP); v5 - add Appdx B, cause classification/frames (not in EJP); v7 - unusual model case; v8 add references
КОМФОРТНАЯ СРЕДА ПЛЯЖНЫХ ДЕСТИНАЦИЙ КАК ПОКАЗАТЕЛЬ КАЧЕСТВЕННОГО СЕРВИСА
Creators: name: СОЛНЦЕВА ОКСАНА ГЛЕБОВНА
name: СЕМЕНОВА ЛЮДМИЛА ВАЛЕРЬЕВНА
name: САРАЙКИНА СВЕТЛАНА ВАСИЛЬЕВНА
name: ЧУГУНОВА ТАТЬЯНА НИКОЛАЕВНА
name: ДЫШЛОВОЙ ИГОРЬ НИКОЛАЕВИЧ
Publisher: name: Сервис в России и за рубежом
Year: 2020
Subjects: ДЕСТИНАЦИИ
ПЛЯЖНЫЕ ДЕСТИНАЦИИ
КОМФОРТНАЯ СРЕДА
КАЧЕСТВО СЕРВИСА
РЕСПУБЛИКА КРЫМ
DESTINATIONS
THE BEACH DESTINATIONS
COMFORTABLE ENVIRONMENT
THE QUALITATIVE SERVICE
REPUBLIC OF CRIMEA

description: В статье рассматривается содержание понятий «пляж» и «пляжная дестинация» как составных частей туристской дестинации. Принципиально важным является анализ природы, структуры и содержания самого понятия «туристская дестинация». Многие теоретические и практические положения развития и функционирования пляжных дестинаций недостаточно освещены в научных публикациях, в частности, слабоизученными остаются вопросы обоснования их комфортной среды и обеспечения качества пляжного отдыха. Пляжные дестинации имеют решающее значение при выборе места проведения отдыха туристов. Результаты исследования показали, что основными составляющими оценки комфортной среды пляжных дестинаций могут стать: 1) определение информационного, экономического, эстетического, бытового и психологического комфорта; 2) оценка окружения туриста; 3) оценка условий, на которые обращает внимание турист при посещении пляжных территорий и которые в большей степени влияют на восприятие комфортного отдыха. Техническая оценка качества пляжного отдыха определяется путем проведения экспертной оценки соответствия оборудования пляжной территории установленным нормам и правилам и носит объективный характер. Восприятие комфорта и получение позитивного впечатления от пляжного отдыха носят субъективный характер и зависят от состояния туриста, от его настроения, от погоды, от его окружения и от множества других внешних и внутренних факторов. Дальнейшие исследования комфортной среды пляжных дестинаций должны осуществляться в рамках единой стратегии, путем проведения экспертных оценок и масштабного анкетирования туристов.
An Assemblage of Lava Flow Features on Mercury
Creators: name: Byrne, Paul K.
name: Klimczak, Christian
name: Williams, David A.
name: Hurwitz, Debra M.
name: Solomon, Sean C.
name: Head, James W.
name: Preusker, Frank
name: Oberst, Jurgen
Publisher: name: Columbia University
Year: 2013
Subjects: Physical geography
Planetary science

description: In contrast to other terrestrial planets, Mercury does not possess a great variety of volcanic features, its history of volcanism instead largely manifest by expansive smooth plains. However, a set of landforms at high northern latitudes on Mercury resembles surface flow features documented on Earth, the Moon, Mars, and Venus. The most striking of such landforms are broad channels that host streamlined islands and that cut through the surrounding intercrater plains. Together with narrower, more sinuous channels, coalesced depressions, evidence for local flooding of intercrater plains by lavas, and a first-order analysis of lava flow rates, the broad channels define an assemblage of flow features formed by the overland flow of, and erosion by, voluminous, high-temperature, low-viscosity lavas. This interpretation is consistent with compositional data suggesting that substantial portions of Mercury's crust are composed of magnesian, iron-poor lithologies. Moreover, the proximity of this partially flooded assemblage to extensive volcanic plains raises the possibility that the formation of these flow features may preface total inundation of an area by lavas emplaced in a flood mode and that they escaped complete burial only due to a waning magmatic supply. Finally, that these broad channels on Mercury are volcanic in nature yet resemble outflow channels on Mars, which are commonly attributed to catastrophic water floods, implies that aqueous activity is not a prerequisite for the formation of such distinctive landforms on any planetary body.
IMRT of Prostate Cancer: A Comparison of Fluence Optimization with Sequential Segmentation and Direct-Step-and-Shoot Optimization
Creators: name: Treutwein, Marius
name: Hipp, Matthias
name: Koelbl, Oliver
name: Bogner, Ludwig
Publisher: name: Universität Regensburg
Year: 2009
Subjects: subject: Direct step and shoot,Direct machine parameter optimization,Intensity-modulated radiation therapy, IMRT,Prostate cancer
subject: 610 Medizin

description: BACKGROUND AND PURPOSE: Intensity-modulated radiation therapy (IMRT) has shown its superiority to three-dimensional conformal radiotherapy in the treatment of prostate cancer. Different optimization algorithms are available: algorithms which first optimize the fluence followed by a sequencing (IM), and algorithms which involve the machine parameters directly in the optimization process (DSS). The aim of this treatment-planning study is to compare both of them regarding dose distribution and treatment time. PATIENTS AND METHODS: Ten consecutive patients with localized prostate cancer were enrolled for the planning study. The planning target volume and the rectum volume, urinary bladder and femoral heads as organs at risk were delineated. Average doses, the target dose homogeneity H, D(5), D(95), monitor units per fraction, and the number of segments were evaluated. RESULTS: While there is only a small difference in the mean doses at rectum and bladder, there is a significant advantage for the target dose homogeneity in the DSS-optimized plans compared to the IM-optimized ones. Differences in the monitor units (nearly 10% less for DSS) and the number of segments are also statistically significant and reduce the treatment time. CONCLUSION: Particularly with regard to the tumor control probability, the better homogeneity of the DSS-optimized plans is more profitable. The shorter treatment time is an improvement regarding intrafractional organ motion. The DSS optimizer results in a higher target dose homogeneity and, simultaneously, in a lower number of monitor units. Therefore, it should be preferred for IMRT of prostate cancer.
Microbial Stimulation and Succession following a Test Well Injection Simulating CO2 Leakage into a Shallow Newark Basin Aquifer
Creators: name: O'Mullan, Gregory D.
name: Dueker, M. Elias
name: Clauson, Kale
name: Yang, Qiang
name: Umemoto, Kelsey
name: Zakharova, Natalia
name: Matter, Juerg M.
name: Stute, Martin
name: Takahashi, Taro
name: Goldberg, David S.
Publisher: name: Columbia University
Year: 2015
Subjects: subject: Geochemistry
subject: FOS: Earth and related environmental sciences
subject: Biogeochemistry
subject: Aquifers
subject: Carbon dioxide
subject: Water--Microbiology

description: In addition to efforts aimed at reducing anthropogenic production of greenhouse gases, geological storage of CO2 is being explored as a strategy to reduce atmospheric greenhouse gas emission and mitigate climate change. Previous studies of the deep subsurface in North America have not fully considered the potential negative effects of CO2 leakage into shallow drinking water aquifers, especially from a microbiological perspective. A test well in the Newark Rift Basin was utilized in two field experiments to investigate patterns of microbial succession following injection of CO2-saturated water into an isolated aquifer interval, simulating a CO2 leakage scenario. A decrease in pH following injection of CO2 saturated aquifer water was accompanied by mobilization of trace elements (e.g. Fe and Mn), and increased bacterial cell concentrations in the recovered water. 16S ribosomal RNA gene sequence libraries from samples collected before and after the test well injection were compared to link variability in geochemistry to changes in aquifer microbiology. Significant changes in microbial composition, compared to background conditions, were found following the test well injections, including a decrease in Proteobacteria, and an increased presence of Firmicutes, Verrucomicrobia and microbial taxa often noted to be associated with iron and sulfate reduction. The concurrence of increased microbial cell concentrations and rapid microbial community succession indicate significant changes in aquifer microbial communities immediately following the experimental CO2 leakage event. Samples collected one year post-injection were similar in cell number to the original background condition and community composition, although not identical, began to revert toward the pre-injection condition, indicating microbial resilience following a leakage disturbance. This study provides a first glimpse into the in situ successional response of microbial communities to CO2 leakage after subsurface injection in the Newark Basin and the potential microbiological impact of CO2 leakage on drinking water resources.
FBS 0107-082: A Symbiotic Binary in a Rare Prolonged Outburst?
Creators: name: Honeycutt, R. K.
name: Kafka, S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: FBS0107-082 is an emission line object previously classified as a nova-like cataclysmic variable star. New optical spectroscopy shows very strong hydrogen Balmer lines, along with a nebular forbidden line spectrum and absorption features from an early-F photosphere. When combined with other IR and optical data from the literature, these data point to the object being a symbiotic nova seen in a prolonged outburst. Photometry on time scales of minutes, days, and years show only very weak variability.
description: Accepted at the Astronomical Journal
РАЗВИТИЕ ТУРИСТСКИХ ПОТОКОВ И ОСОБЕННОСТИ ИХ СЕГМЕНТАЦИИ
Creators: name: САРЯН АКОП АЙГАЗОВИЧ
name: ОБОРИН МАТВЕЙ СЕРГЕЕВИЧ
Publisher: name: Сервис в России и за рубежом
Year: 2020
Subjects: ТУРИЗМ
ТУРИСТСКИЕ ПОТОКИ
СЕГМЕНТАЦИЯ
МОДЕРНИЗАЦИЯ
ДИФФЕРЕНЦИАЦИЯ
СЕГМЕНТИРОВАНИЕ
ПРОФИЛЬ ПОТРЕБИТЕЛЯ
TOURISM
TOURIST FLOWS
SEGMENTATION
MODERNIZATION
DIFFERENTIATION
CONSUMER PROFILE

description: Статья посвящена анализу факторов влияния и особенностей формирования туристских потоков в России. Поскольку туристско-рекреационная сфера является динамично растущим сегментом экономики, стимулирование ее развития оказывает положительное воздействие на социально-экономическое развитие субъектов, способствует сглаживанию территориальных диспропорций и перераспределению доходов. Предметом исследования является туристский поток, его физические характеристики. Цель - выявление особенностей сегментации туристского потока как направления совершенствования предложения услуг на региональном уровне. Гипотеза исследования заключается в предположении о том, что сформированный в результате маркетинговых исследований профиль потребителя будет оказывать влияние на структуру и качество туристских услуг в субъектах страны. Результаты работы заключаются в исследовании статистических показателей туристского потока в России и определении основных структурных элементов профиля потребителя услуг, который будет оказывать влияние на формирование регионального предложения. Основные направления будущих исследования связаны с разработкой теоретикометодических основ оценки маркетинговых стратегий на рост туристского потока в регионах страны с туристско-рекреационной специализацией.
A New Email Retrieval Ranking Approach
Creators: name: AbdelRahman, Samir
name: Hassan, Basma
name: Bahgat, Reem
Publisher: name: arXiv
Year: 2010
Subjects: subject: Information Retrieval (cs.IR)
subject: FOS: Computer and information sciences

description: Email Retrieval task has recently taken much attention to help the user retrieve the email(s) related to the submitted query. Up to our knowledge, existing email retrieval ranking approaches sort the retrieved emails based on some heuristic rules, which are either search clues or some predefined user criteria rooted in email fields. Unfortunately, the user usually does not know the effective rule that acquires best ranking related to his query. This paper presents a new email retrieval ranking approach to tackle this problem. It ranks the retrieved emails based on a scoring function that depends on crucial email fields, namely subject, content, and sender. The paper also proposes an architecture to allow every user in a network/group of users to be able, if permissible, to know the most important network senders who are interested in his submitted query words. The experimental evaluation on Enron corpus prove that our approach outperforms known email retrieval ranking approaches
description: 20 pages
Microbial Community Structure and Arsenic Biogeochemistry in Two Arsenic-Impacted Aquifers in Bangladesh
Creators: name: Gnanaprakasam, Edwin T.
name: Lloyd, Jonathan R.
name: Boothman, Christopher
name: Ahmed, Kazi Matin
name: Choudhury, Imtiaz
name: Bostick, Benjamin C.
name: Van Geen, Alexander
name: Mailloux, Brian J.
Publisher: name: Columbia University
Year: 2017
Subjects: Biogeochemistry
Geomicrobiology
Groundwater--Arsenic content
Aquifers
Sediments (Geology)--Microbiology

description: Long-term exposure to trace levels of arsenic (As) in shallow groundwater used for drinking and irrigation puts millions of people at risk of chronic disease. Although microbial processes are implicated in mobilizing arsenic from aquifer sediments into groundwater, the precise mechanism remains ambiguous. The goal of this work was to target, for the first time, a comprehensive suite of state-of-the-art molecular techniques in order to better constrain the relationship between indigenous microbial communities and the iron and arsenic mineral phases present in sediments at two well-characterized arsenic-impacted aquifers in Bangladesh. At both sites, arsenate [As(V)] was the major species of As present in sediments at depths with low aqueous As concentrations, while most sediment As was arsenite [As(III)] at depths with elevated aqueous As concentrations. This is consistent with a role for the microbial As(V) reduction in mobilizing arsenic. 16S rRNA gene analysis indicates that the arsenic-rich sediments were colonized by diverse bacterial communities implicated in both dissimilatory Fe(III) and As(V) reduction, while the correlation analyses involved phylogenetic groups not normally associated with As mobilization. Findings suggest that direct As redox transformations are central to arsenic fate and transport and that there is a residual reactive pool of both As(V) and Fe(III) in deeper sediments that could be released by microbial respiration in response to hydrologic perturbation, such as increased groundwater pumping that introduces reactive organic carbon to depth. IMPORTANCE: The consumption of arsenic in waters collected from tube wells threatens the lives of millions worldwide and is particularly acute in the floodplains and deltas of southern Asia. The cause of arsenic mobilization from natural sediments within these aquifers to groundwater is complex, with recent studies suggesting that sediment-dwelling microorganisms may be the cause. In the absence of oxygen at depth, specialist bacteria are thought able to use metals within the sediments to support their metabolism. Via these processes, arsenic-contaminated iron minerals are transformed, resulting in the release of arsenic into the aquifer waters. Focusing on a field site in Bangladesh, a comprehensive, multidisciplinary study using state-of-the-art geological and microbiological techniques has helped better understand the microbes that are present naturally in a high-arsenic aquifer and how they may transform the chemistry of the sediment to potentially lethal effect.
Free Energy of ABJM Theory
Creators: name: Smedbäck, Mikael
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The free energy of ABJM theory has previously been computed in the strong and weak coupling limits. In this note, we report on results for the computation of the first non-vanishing quantum correction to the free energy, from the field theory side. The correction can be expressed in terms of a thermal mass for the scalar fields. This mass vanishes to 1-loop order, but there is a non-vanishing result to 2-loop order. Hence, the leading correction to the free energy is non-analytic in the 't Hooft coupling constant lambda. The reason is that the infrared divergences necessitate a resummation of ring diagrams and a related reorganization of perturbation theory, in which already the leading correction receives contributions from all orders in lambda. These results suggest that the free energy interpolates smoothly between weak and strong coupling.
description: 6 pages. Contribution to the proceedings of the 16th European Workshop on String Theory 2010, Real Jardin Botanico, Madrid, 14-18 June 2010. v2: published version
ПРОБЛЕМЫ ИСПОЛЬЗОВАНИЯ СОВРЕМЕННОГО ИНСТРУМЕНТАРИЯ ДЛЯ СОЗДАНИЯ ИНТЕРАКТИВНЫХ ТУРИСТСКИХ ВЕБ-КАРТ И ГЕОПОРТАЛОВ
Creators: name: ЯКИМОВА СВЕТЛАНА ЛЕОНИДОВНА
name: САРАНЧА МИХАИЛ АЛЕКСАНДРОВИЧ
Publisher: name: Сервис в России и за рубежом
Year: 2020
Subjects: ГЕОИНФОРМАЦИОННЫЕ ТЕХНОЛОГИИ
ГЕОПОРТАЛ
МОСКОВСКАЯ ОБЛАСТЬ
ПРОБЛЕМЫ
ТУРИЗМ
ИНТЕРАКТИВНАЯ ВЕБ-КАРТА
GEOINFORMATION TECHNOLOGIES
GEOPORTAL
MOSCOW REGION
PROBLEMS
TOURISM
WEB MAP

description: Информационно-коммуникационные технологии на современном этапе выступают одними из ключевых факторов развития туризма. Геоинформационные веб-сервисы получают все большее свое распространение и область применения. Однако, их внедрение сдерживается широким спектром проблем. Предмет исследования определяется его целью и охватывает базовые проблемы использования программного обеспечения для создания интерактивных туристских веб-карт и геопорталов. Основными методами исследования выступили: картографический, сравнительный, аналогий, моделирование, математико-статистический, анализа и синтеза, описательный и др.; основными исследовательскими подходами - геоинформационный, географический, системный, комплексный и ситуативный. В рамках исследования были выделены и рассмотрены следующие проблемы: «высокий порог» вхождения по сложности технологий и затратам на них, недостаточного количества квалифицированных специалистов и законченного методического обеспечения, необходимости создания междисциплинарных творческих коллективов (веб-программистов, картографов, дизайнеров, специалистов в сфере туризма и др.), сбора, хранения и обработки качественных и достаточных по объемам данных, обеспечения полезности и эргономичности использования веб-карт пользователями, слабой заинтересованности в развитии сервисов крупных лидеров рынка информационных технологий и др. Рассмотрение проблем было проведено через призму основных программных продуктов, обеспечивающих решение базовых задач создания интерактивных туристских веб-карт и геопорталов. Апробация проведена на основе созанного туристского геопортала озера Байкал, а также создаваемых интерактивных туристских карт Московской области в рамках реализации инновационной модели проектного обучения студентов ФГБОУ ВО «Российский государственный университет туризма и сервиса».
Zertifizierung einer Translationsliege zur Ganzkörperbestrahlung aus In-Haus-Herstellung gemäß dem Medizinproduktegesetz
Creators: name: Scherf, Christian
name: Härtl, Petra
name: Treutwein, Marius
name: Bogner, Ludwig
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: Ganzkörperbestrahlung, In-Haus- Herstellung, Medizinproduktegesetz, funktionale Sicherheit, Total body irradiation, in-house manufacture, Medical Devices Act, functional safety
subject: 600 Technik
subject: 610 Medizin

description: A new translational couch unit with extended potentials of dose optimization by variable velocity and a comfortable user interface with integrated patient administration was developed at the university clinic of Regensburg. MATERIALS AND METHODS: The concept and construction were elaborated in legal accordance with the in-house manufacture conditions mentioned in the German Medical Devices Act. In particular we have implemented a concept of functional safety based on a controller unit, an independent monitoring unit and self-testing procedures. Redundant safety relevant hard- and software components are continuously checked against each other. In case of any malfunction the translation movement and the linear accelerator are stopped. Gap-free continuation of the treatment will be possible after elimination of the cause of the interrupt. RESULTS AND CONCLUSION: After the testing of the implemented functional safety features including the risk assessment and management, electrical safety, electromagnetic compatibility by accredited technical experts the translational couch system complies with the requirements of the Medical Devices Act and can be operated in terms of in-house application. The presented certification procedure can motivate other radiation departments to develop own systems for in-house usage.
description: Article in german
Unconventional Gas and Oil Drilling Is Associated with Increased Hospital Utilization Rates
Creators: name: Jemielita, Thomas
name: Gerton, George L.
name: Neidell, Matthew J.
name: Chillrud, Steven N.
name: Yan, Beizhan
name: Stute, Martin
name: Howarth, Marilyn
name: Saberi, Pouné
name: Fausti, Nicholas
name: Penning, Trevor M.
name: Roy, Jason
name: Propert, Kathleen J.
name: Panettieri Jr., Reynold A.
Publisher: name: Columbia University
Year: 2015
Subjects: Oil well drilling
Gas well drilling
Fossil fuels--Environmental aspects
Hospital utilization

description: Over the past ten years, unconventional gas and oil drilling (UGOD) has markedly expanded in the United States. Despite substantial increases in well drilling, the health consequences of UGOD toxicant exposure remain unclear. This study examines an association between wells and healthcare use by zip code from 2007 to 2011 in Pennsylvania. Inpatient discharge databases from the Pennsylvania Healthcare Cost Containment Council were correlated with active wells by zip code in three counties in Pennsylvania. For overall inpatient prevalence rates and 25 specific medical categories, the association of inpatient prevalence rates with number of wells per zip code and, separately, with wells per km2 (separated into quantiles and defined as well density) were estimated using fixed-effects Poisson models. To account for multiple comparisons, a Bonferroni correction with associations of p<0.00096 was considered statistically significant. Cardiology inpatient prevalence rates were significantly associated with number of wells per zip code (p<0.00096) and wells per km2 (p<0.00096) while neurology inpatient prevalence rates were significantly associated with wells per km2 (p<0.00096). Furthermore, evidence also supported an association between well density and inpatient prevalence rates for the medical categories of dermatology, neurology, oncology, and urology. These data suggest that UGOD wells, which dramatically increased in the past decade, were associated with increased inpatient prevalence rates within specific medical categories in Pennsylvania. Further studies are necessary to address healthcare costs of UGOD and determine whether specific toxicants or combinations are associated with organ-specific responses.
Alkylcyanoacrylate drug carriers: I. Physicochemical characterization of nanoparticles with different alkyl chain length
Creators: name: Müller, R. H.
name: Lherm, C.
name: Herbort, J.
name: Blunk, Torsten
name: Couvreur, P.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: 615 Pharmazie

description: Alkylcyanoacrylate particles were physico-chemically characterized in terms of size, surface charge, zeta potential, interaction with charged serum components and surface hydrophobicity as relevant parameters influencing the in vitro interaction with cells in culture and the in vivo organ distribution and fate after intravenous administration. Methyl-, ethyl-, isobutyl- and isohexyl-cyanoacrylate particles were found to be very similar with regard to these properties. Large differences existed with regard to their degradation behaviour. The type of degradation (surface erosion) was determined by photon correlation spectroscopy, and the degradation velocity was evaluated using a turbidimetric assay. Surface modification of the particles by a polymer coating affected neither the type nor the velocity of the degradation.
КОНЦЕПЦИЯ ОРГАНИЗАЦИИ БИЗНЕС-МОДЕЛЕЙ НА БАЗЕ ЦИФРОВОЙ ИНФОРМАЦИОННОЙ ПЛАТФОРМЫ
Creators: name: ХАЙРУЛЛИНА ЭЛЬМИРА РОБЕРТОВНА
Publisher: name: Сервис в России и за рубежом
Year: 2020
Subjects: ЦИФРОВАЯ ИНФОРМАЦИОННАЯ ПЛАТФОРМА
ИНФОКОММУНИКАЦИОННЫЕ ТЕХНОЛОГИИ
БИЗНЕС-МОДЕЛЬ
ОПЕРАТОР IT-УСЛУГ
ЭФФЕКТИВНОСТЬ СИСТЕМЫ
DIGITAL INFORMATION PLATFORM
INFORMATION AND COMMUNICATION TECHNOLOGIES
BUSINESS MODEL
IT SERVICES OPERATOR
SYSTEM EFFICIENCY

description: В статье сформирована структура бизнес-системы с элементами MaaS - технологий как сети, состоящей из большого числа взаимосвязанных участников, извлекающих выгоду «друг из друга» и взаимной эффективности, определены уровни субъектных связей в системе, а также направления информационных, финансовых и нормативнорегуляторных потоков. Услуги, основанные на цифровой информационной платформе MaaS позволяют формировать новые способы управления предложениями отдельных поставщиков услуг, что требует разработки универсальных схем бизнес-моделей операторов системы MaaS, раскрывающих широкий спектр ключевых партнеров и клиентов, а также источников дохода. Модель ГЧП может быть особенно подходящей в сельских или малонаселенных районах, где сочетание логистических услуг, а также транспортировки школьных и государственных социальных услуг с MaaS важно для эффективности и поддержания соответствующего уровня социального обслуживания.