cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1 of The association between initial calculated driving pressure at the induction of general anesthesia and composite postoperative oxygen support
Creators: name: Hosokawa, Koji
name: Tanaka, Katsuya
name: Ishihara, Kayo
name: Yamazaki, Yukiko
name: Matsuki, Yuka
name: Shigemi, Kenji
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Mental Health

description: Additional file 1: Supplemental Figure 1. Data collection process. Crs, respiratory system compliance; GA, general anesthesia; POS, postoperative oxygen support. Supplemental Figure 2. Subgroup analysis of prolonged postoperative oxygen support Subgroup analysis has been conducted for the age, American Society of Anesthesiologist (ASA) physical status, surgical schedule, and the duration of anesthesia. Subjects have been divided into five categories according to the driving pressure (dP). Considering a reference dP of 6.5–8.3 cmH2O, an association is observed between high dPs and high odds ratio for prolonged postoperative oxygen therapy in the young age group with low score of ASA physical status and short duration of anesthesia. Supplemental Table 1. Respiratory parameters at the induction of general anesthesia Values are presented as medians [interquartile ranges]. PCV-VG, pressure-controlled ventilation with volume guarantee. Supplemental Table 2. Prolonged postoperative oxygen support. Values are presented as medians [interquartile ranges]. ASA, American Society of Anesthesiologists; ICU, intensive care unit; PCV-VG, pressure-controlled ventilation with volume guarantee. Supplemental Table 3. Patient characteristics among the five driving pressure categories. Values are presented as percentages or medians [interquartile ranges]. ASA, American Society of Anesthesiologists. Supplemental Table 4. Subgroup analysis of prolonged postoperative oxygen support. Prolonged postoperative oxygen support was defined as ≥ 3 days of oxygen therapy after surgery. The Odds ratio was adjusted for age, American Society of Anesthesiologist physical status, and duration of anesthesia. * statistical significance. n.a., not applicable.
Appendices_EB_28.08 – Supplemental material for The Transmission of Energy-Saving Behaviors in the Family: A Multilevel Approach to the Assessment of Aggregated and Single Energy-Saving Actions of Parents and Adolescents
Creators: name: Wallis, Hannah
name: Klöckner, Christian
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Appendices_EB_28.08 for The Transmission of Energy-Saving Behaviors in the Family: A Multilevel Approach to the Assessment of Aggregated and Single Energy-Saving Actions of Parents and Adolescents by Hannah Wallis and Christian Klöckner in Environment and Behavior
Additional file 1 of Focused Ultrasound and RadioTHERapy for non-invasive palliative pain treatment in patients with bone metastasis: a study protocol for the three armed randomized controlled FURTHER trial
Creators: name: Slotman, Derk J.
name: Bartels, Marcia M. T. J.
name: Ferrer, Cyril J.
name: Bos, Clemens
name: Bartels, Lambertus W.
name: Boomsma, Martijn F.
name: Phernambucq, Erik C. J.
name: Nijholt, Ingrid M.
name: Morganti, Alessio G.
name: Siepe, Giambattista
name: Buwenge, Milly
name: Grüll, Holger
name: Bratke, Grischa
name: Yeo, Sin Yuin
name: Blanco Sequeiros, Roberto
name: Minn, Heikki
name: Huhtala, Mira
name: Napoli, Alessandro
name: De Felice, Francesca
name: Catalano, Carlo
name: Bazzocchi, Alberto
name: Gasperini, Chiara
name: Campanacci, Laura
name: Simões Corrêa Galendi, Julia
name: Müller, Dirk
name: Braat, Manon N. G. J. A.
name: Moonen, Chrit
name: Verkooijen, Helena M.
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Additional file 1. Informed consent form (Dutch version).
Migratory movement of photo-identified humpback whales Megaptera novaeangliae along the southeastern coast of Africa
Creators: name: Tree, B
name: Olbers, J
name: Seyboth, E
name: Seakamela, SM
name: Cockcroft, VG
name: Vermeulen, E
name: Findlay, KP
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: The global conservation of humpback whales Megaptera novaeangliae relies on continuous assessments of the populations’ post-whaling status, which in turn require information on population mixing and movements. One of the seven breeding stocks in the Southern Hemisphere, breeding stock C and its associated four substocks (C1–C4), utilises the western Indian Ocean in several discrete breeding grounds. However, information on the mixing of stocks across breeding grounds is limited. This study utilises photo-identification methods applied to the first multi-regional catalogue of fluke images available for substock C1S (the southern component of substock C1) which uses the southern portion of the breeding ground, developed as part of this study, to investigate the whales’ movements along the southeastern coast of southern Africa. The identification of 1 746 unique individuals, including 11 withinyear matches and 48 between-year matches of 45 individuals, provides new insight into the intra-regional migration patterns, fidelity and structure of substock C1S. The within-year match results confirmed that individual humpback whales are broadly seasonally present for extended periods and visit multiple subregions along this coast, while the between-year matches revealed long-term fidelity to this coastline. Moreover, five of the between-year matches between subregions in South Africa and Mozambique linked the South African migration corridor to the breeding ground in southern and central Mozambique. These findings provide valuable insights into the movement patterns of substock C1S and significantly address the challenges of effective population management, which includes difficulties associated with the whale-watching industry on the east coast of South Africa.
The effect of preventative cardiovascular therapies on coronary artery disease in people with and without type 2 diabetes: a propensity-matched score study
Creators: name: Kiburg, Katerina
name: MacIsaac, AI
name: McCluskey, GE
name: Sundararajan, Vijaya
name: MacIsaac, RJ
Publisher: name: La Trobe
Year: 2021

description: Background: Although it is known that patients with Type 2 Diabetes Mellitus (T2DM) are at an increased risk of coronary artery disease (CAD), the actual coronary artery burden of atherosclerotic disease in patients with and without T2DM in a real-world setting and its possible modification by preventative therapies has not been extensively documented. Methods: Merged coronary angiography and hospital discharge data between 2013 and 2019 were obtained for analysis and a random sub-sample of patient charts were reviewed for medication use. Propensity scores were estimated using logistic regression models and used to match patients, looking at the effect of severity of CAD over time in years in an ordinal logistic regression model. A separate propensity score was estimated and used to inverse probability weight the ordinal logistic regression looking at the effect of medication use on CAD severity in patients with and without T2DM. Results: From 3,016 patients in the coronary angiography database, 1421 with T2DM and 1421 without T2DM were matched on propensity score. T2DM patients had more extensive CAD in 2018 compared to 2013 ((adjusted odds ratio) adjOR: 2.06 95% C.I. 1.38, 2.07), but this risk appeared to be attenuated in 2019. In contrast, there was no effect of time on CAD burden in patients without diabetes. In the sub-sample of 760 patients who underwent a chart review of their medication use, there were 367 (48%) with T2DM. For patients with T2DM 69.8% reported taking statins, 64.0% RAS inhibitors and 64.0% anti-platelet drugs. This was significantly higher than patients without diabetes of whom 46.6% reported taking statins, 49.0% RAS inhibitors and 49.9% anti-platelet drugs. As in the full matched sample, patients with diabetes had more extensive CAD (adjOR: 1.32 95% CI: 1.01, 1.74). However, after adjustment for the use of RAS inhibitors, statins and anticoagulants there was no difference in extent of CAD between patients with and without diabetes (adjOR: 1.14 95% CI: 0.85, 1.53). Conclusions: Although patients with diabetes have a greater extent of CAD in comparison to those without T2DM, preventative medication use decreases this CAD burden significantly.
Appendix 1 - Supplemental material for Assessment of Attractants for Neotropical Mammals
Creators: name: Duarte, Herbert De Oliveira Barbosa
name: Norris, Darren
name: Michalski, Fernanda
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Geography
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, Appendix 1 for Assessment of Attractants for Neotropical Mammals by Herbert de Oliveira Barbosa Duarte, Darren Norris and Fernanda Michalski in Tropical Conservation Science
The effect of preventative cardiovascular therapies on coronary artery disease in people with and without type 2 diabetes: a propensity-matched score study
Creators: name: Kiburg, Katerina
name: MacIsaac, AI
name: McCluskey, GE
name: Sundararajan, Vijaya
name: MacIsaac, RJ
Publisher: name: La Trobe
Year: 2021
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3201
subject: Cardiovascular medicine and haematology

description: Background: Although it is known that patients with Type 2 Diabetes Mellitus (T2DM) are at an increased risk of coronary artery disease (CAD), the actual coronary artery burden of atherosclerotic disease in patients with and without T2DM in a real-world setting and its possible modification by preventative therapies has not been extensively documented. Methods: Merged coronary angiography and hospital discharge data between 2013 and 2019 were obtained for analysis and a random sub-sample of patient charts were reviewed for medication use. Propensity scores were estimated using logistic regression models and used to match patients, looking at the effect of severity of CAD over time in years in an ordinal logistic regression model. A separate propensity score was estimated and used to inverse probability weight the ordinal logistic regression looking at the effect of medication use on CAD severity in patients with and without T2DM. Results: From 3,016 patients in the coronary angiography database, 1421 with T2DM and 1421 without T2DM were matched on propensity score. T2DM patients had more extensive CAD in 2018 compared to 2013 ((adjusted odds ratio) adjOR: 2.06 95% C.I. 1.38, 2.07), but this risk appeared to be attenuated in 2019. In contrast, there was no effect of time on CAD burden in patients without diabetes. In the sub-sample of 760 patients who underwent a chart review of their medication use, there were 367 (48%) with T2DM. For patients with T2DM 69.8% reported taking statins, 64.0% RAS inhibitors and 64.0% anti-platelet drugs. This was significantly higher than patients without diabetes of whom 46.6% reported taking statins, 49.0% RAS inhibitors and 49.9% anti-platelet drugs. As in the full matched sample, patients with diabetes had more extensive CAD (adjOR: 1.32 95% CI: 1.01, 1.74). However, after adjustment for the use of RAS inhibitors, statins and anticoagulants there was no difference in extent of CAD between patients with and without diabetes (adjOR: 1.14 95% CI: 0.85, 1.53). Conclusions: Although patients with diabetes have a greater extent of CAD in comparison to those without T2DM, preventative medication use decreases this CAD burden significantly.
Impact-Resistant and Tough 3D Helicoidally Architected Polymer Composites Enabling Next-Generation Lightweight Silicon Photovoltaics Module Design and Technology
Creators: name: Budiman, Arief Suriadi
name: Sahay, Rahul
name: Agarwal, Komal
name: Illya, Gregoria
name: Widjaja, Ryo Geoffrey
name: Baji, Avinash
name: Raghavan, Nagarajan
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Lightweight photovoltaics (PV) modules are important for certain segments of the renewable energy markets—such as exhibition halls, factories, supermarkets, farms, etc. However, lightweight silicon-based PV modules have their own set of technical challenges or concerns. One of them, which is the subject of this paper, is the lack of impact resistance, especially against hailstorms in deep winter in countries with four seasons. Even if the front sheet can be made sufficiently strong and impact-resistant, the silicon cells inside remain fragile and very prone to impact loading. This leads to cracks that significantly degrade performance (output power) over time. A 3D helicoidally architected fiber-based polymer composite has recently been found to exhibit excellent impact resistance, inspired by the multi-hierarchical internal structures of the mantis shrimp’s dactyl clubs. In previous work, our group demonstrated that via electrospinning-based additive manufacturing methodologies, weak polymer material constituents could be made to exhibit significantly improved toughness and impact properties. In this study, we demonstrate the use of 3D architected fiber-based polymer composites to protect the silicon solar cells by absorbing impact energy. The absorbed energy is equivalent to the energy that would impact the solar cells during hailstorms. We have shown that silicon cells placed under such 3D architected polymer layers break at substantially higher impact load/energy (compared to those placed under standard PV encapsulation polymer material). This could lead to the development of novel PV encapsulant materials for the next generation of lightweight PV modules and technology with excellent impact resistance.
Australian lizards are outstanding models for reproductive biology research
Creators: name: Van Dyke, James
name: Thompson, MB
name: Burridge, CP
name: Castelli, MA
name: Clulow, S
name: DIssanayake, DSB
name: Dong, CM
name: Doody, JS
name: Edwards, DL
name: Ezaz, T
name: Friesen, CR
name: Gardner, MG
name: Georges, A
name: Higgie, M
name: Hill, PL
name: Holleley, CE
name: Hoops, D
name: Hoskin, CJ
name: Merry, DL
name: Riley, JL
name: Wapstra, E
name: While, GM
name: Whiteley, SL
name: Whiting, MJ
name: Zozaya, SM
name: Whittington, CM
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Australian lizards are a diverse group distributed across the continent and inhabiting a wide range of environments. Together, they exhibit a remarkable diversity of reproductive morphologies, physiologies, and behaviours that is broadly representative of vertebrates in general. Many reproductive traits exhibited by Australian lizards have evolved independently in multiple lizard lineages, including sociality, complex signalling and mating systems, viviparity, and temperature-dependent sex determination. Australian lizards are thus outstanding model organisms for testing hypotheses about how reproductive traits function and evolve, and they provide an important basis of comparison with other animals that exhibit similar traits. We review how research on Australian lizard reproduction has contributed to answering broader evolutionary and ecological questions that apply to animals in general. We focus on reproductive traits, processes, and strategies that are important areas of current research, including behaviours and signalling involved in courtship; mechanisms involved in mating, egg production, and sperm competition; nesting and gestation; sex determination; and finally, birth in viviparous species. We use our review to identify important questions that emerge from an understanding of this body of research when considered holistically. Finally, we identify additional research questions within each topic that Australian lizards are well suited for reproductive biologists to address.
Interventions Targeting the Wellbeing of Migrant Youths: A Systematic Review of the Literature
Creators: name: Heyeres, Marion
name: Perera, Nirukshi
name: Udah, Hyacinth
name: Attakey, Akpene
name: Whiteside, Mary
name: Tsey, Komla
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Migration can affect the physical, mental, emotional, and social wellbeing of individuals and families. This study provides an overview of interventions aimed at improving the wellbeing of young migrants. It identifies knowledge gaps and provides direction for future research. The review process comprises a systematic search of six academic databases, and websites for relevant peer-reviewed and gray literature on the topic. A total of 2,911 records were identified, of which 28 studies met our eligibility criteria for inclusion. Thematic analysis comprised of the description of study characteristics and outcome themes. EPHPP and CASP tools were utilized to assess the methodological quality of studies. The review findings indicate a number of approaches with varying effectivity, however, arts, music, and sports programs showed good results for youth across all migrant groups. Our findings call for further and more high-quality evaluation research, with longitudinal designs that ideally include stakeholder collaboration.
The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury
Creators: name: Ataei, Maryam Lale
name: Karimipour, Mohammad
name: Shahabi, Parviz
name: Pashaei-Asl, Roghiyeh
name: Ebrahimie, Esmaeil
name: Pashaiasl, Maryam
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Spinal cord injury (SCI) is a debilitating condition within the neural system which is clinically manifested by sensory-motor dysfunction, leading, in some cases, to neural paralysis for the rest of the patient’s life. In the current study, mesenchymal stem cells (MSCs) were isolated from the human amniotic fluid, in order to study their juxtacrine and paracrine activities. Flow cytometry analysis was performed to identify the MSCs. A conditioned medium (CM) was collected to measure the level of BDNF, IL-1β, and IL-6 proteins using the ELISA assay. Following the SCI induction, MSCs and CM were injected into the lesion site, and also CM was infused intraperitoneally in the different groups. Two weeks after SCI induction, the spinal cord samples were examined to evaluate the expression of the doublecortin (DCX) and glial fibrillary acid protein (GFAP) markers using immunofluorescence staining. The MSCs’ phenotype was confirmed upon the expression and un-expression of the related CD markers. Our results show that MSCs increased the expression level of the DCX and decreased the level of the GFAP relative to the injury group (p < 0.001). Additionally, the CM promoted the DCX expression rate (p < 0.001) and decreased the GFAP expression rate (p < 0.01) as compared with the injury group. Noteworthily, the restorative potential of the MSCs was higher than that of the CM (p < 0.01). Large-scale meta-analysis of transcriptomic data highlighted PAK5, ST8SIA3, and NRXN1 as positively coexpressed genes with DCX. These genes are involved in neuroactive ligand–receptor interaction. Overall, our data revealed that both therapeutic interventions could promote the regeneration and restoration of the damaged neural tissue by increasing the rate of neuroblasts and decreasing the astrocytes.
Do Deposit Insurance Systems Promote Banking Stability?
Creators: name: Alam, Nafis
name: Sivarajah, Ganesh
name: Bhatti, Ishaq
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: During the global financial crisis (GFC), regulators and policymakers turned to deposit insurers, along with monetary and fiscal measures, to help restore market confidence and promote financial stability. These events have focused attention on the role of deposit insurers and their role in the banking system. Recent literature reveals that during the GFC, deposit insurance maintained banking stability and successfully prevented customers doing ‘runs’ on the banks. The objective of this paper is to examine the deposit insurance system’s coverage limits and the impact on banking stability, in the context of a jurisdiction’s economic and institutional environment. Our model examines 61 jurisdictions in Asia and Europe with explicit deposit insurance systems, covering the pre- and post-GFC period between 2004 and 2014. We also examine subsets to investigate the effects of the region by comparing Asia and Europe, as well as a subset using the date of establishment of the deposit insurance system to understand if maturity matters. The results indicate that deposit insurance systems, and specifically deposit insurance coverage levels, have both positive and negative effects on banking stability. We find significant associations with certain economic and institutional factors; however, there are differences between the models we ran. These can be ascribed to regional factors and the date of when a deposit insurance system was established.
From Auto-Bäcklund Transformations to Auto-Bäcklund Transformations, and Torqued ABS Equations
Creators: name: Zhang, DD
name: Zhang, DJ
name: Van Der Kamp, Pieter
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 49
subject: Mathematical sciences
classificationCode: 4904
subject: Pure mathematics
classificationCode: 51
subject: Physical sciences
subject: FOS: Physical sciences

description: No
description supplied
Building a rural workforce through identifying supports for rural, mature-aged nursing and allied health students: A systematic scoping review
Creators: name: Quilliam, Claire
name: Crawford, Nicole
name: McKinstry, Carol
name: Shee, Anna Wong
name: Harvey, Pamela
name: Glenister, Kristen
name: Sutton, Keith
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems

description: Introduction: There is a long-standing undersupply of nursing and allied health professionals in rural Australia. Rural, mature-aged people form an untapped section of rural communities that could help to address these workforce needs. There is little understanding of the supports required to assist rural, mature-aged nursing and allied health students to complete their studies and enter the rural health workforce. Objective: To scope factors influencing rural, mature-aged nursing and allied health students’ ability to access, participate, and succeed in higher education. Design: A scoping review of the international rural nursing and allied health and education literature was undertaken. Five databases (CINAHL Complete, MEDLINE, Education Resources Information Center [ERIC], Embase, and Education Research Complete), key peer-reviewed journals, and Australian grey literature were searched. Findings: Fourteen articles were included in the review. Ten studies described rural, mature-aged nursing and allied health student characteristics, 6 described barriers to students participating and succeeding in higher education, and 4 described student supports. Discussion: This review found limited evidence to guide higher education providers in attracting, supporting and retaining rural, mature-aged nursing and allied health students. In particular, evidence of student supports is required beyond those manifested by students themselves or their family, to include offerings from university and government sources. Conclusion: Substantially more research attention is needed to understand the experiences of rural, mature-aged nursing and allied health students, and supports required for this cohort to access, participate and successfully complete higher education.
Partitioning the sources of sediment organic carbon in South African seagrass meadows
Creators: name: Bossert, A
name: von der Heyden, S
name: Colling, J
name: Ndhlovu, A
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: In the sediments of seagrass meadows, allochthonous carbon sources can account for 50–90% of sediment organic carbon (SOC), in which non-seagrass carbon is derived from external organic matter advected into the meadow’s sediments or trapped by the seagrass canopy. Identifying the SOC origin is essential to accurately estimate the climate change mitigation potential of seagrass ecosystems, yet the ratio of allochthonous to autochthonous SOC in South African seagrass populations has not been investigated. In this study, we measured the SOC and carbon isotope ratio (δ13C) in Zostera capensis seagrass meadows in the Berg River and Breede River estuaries and applied Bayesian mixing models to disentangle the SOC contributory sources. Sediment organic carbon differed not only between estuaries, but also showed variability within each estuary, with autochthonous carbon accounting for between ∼35% (SD 0.23) and ∼42.3% (SD 0.18) of total meadow SOC. Other sources of SOC included macroalgae, salt marsh and seagrass species. Our work highlights the importance of accounting for allochthonous carbon in disentangling the drivers of high variability of carbon stocks in estuarine environments and contributes to improving the accuracy of South African seagrass carbon stock estimates.
Coronavirus disease 2019 and future pandemics: Impacts on livestock health and production and possible mitigation measures
Creators: name: Haque, MH
name: Islam, MA
name: Karim, MR
name: Kayesh, MEH
name: Sarker, Subir
name: Nazir, KHMNH
name: Anwer, MS
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: The World Health Organization declared coronavirus disease 2019 (COVID-19) a pandemic on March 11, 2020. COVID-19, the current global health emergency, is wreaking havoc on human health systems and, to a lesser degree, on animals globally. The outbreak has continued since the first report of COVID-19 in China in December 2019, and the second and third waves of the outbreak have already begun in several countries. COVID-19 is expected to have adverse effects on crop production, food security, integrated pest control, tourism, the car industry, and other sectors of the global economy. COVID-19 induces a range of effects in livestock that is reflected economically since human health and livelihood are intertwined with animal health. We summarize the potentially harmful effects of COVID-19 on livestock and possible mitigation steps in response to this global outbreak. Mitigation of the negative effects of COVID-19 and future pandemics on livestock requires the implementation of current guidelines.
Contrast in larval sensitivity to low pH in sea urchins from neighbouring seagrass meadows at Inhaca Island, Mozambique
Creators: name: Duvane, JA
name: Cossa, D
name: de Abreu, DC
name: Mafambissa, M
name: Scarlet, MP
name: Macia, A
name: Dupont, S
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Ocean acidification presents a major threat to marine life, and a large body of evidence has documented its negative effects on various marine species and ecosystems. Recent meta-analyses highlight the key role of local adaptation and have linked species’ sensitivity to extremes of the present range of pH variability. More specifically, ‘physiological tipping points’ can be correlated with the lowest experienced pH where the organisms live. We verified this hypothesis by comparing the responses of larvae of the collector urchin Tripneustes gratilla originating from two neighbouring seagrass meadows at Inhaca Island in southern Mozambique. The two seagrass meadows experience different conditions: the site at the Inhaca Marine Biology Research Station (Estação de Biologia Marítima de Inhaca, EBMI) is subtidal, and the site at Banguá is intertidal. Larvae of adults collected from the two sites were cultured in the laboratory under four different target pH treatments (8.04, 7.67, 7.46 and 7.29) for 7 days. The results showed an overall negative effect of lower pH on survival and growth as well as on an index of symmetry. Larvae originating from the intertidal seagrass habitat at Banguá which experiences large pH fluctuations were more sensitive to a lower pH than those from the subtidal seagrass habitat at EBMI. This finding suggests that different mechanisms for pH tolerance and local adaptation may apply in subtidal versus intertidal environments. Consequently, the unifying principle that physiological tipping points are correlated with the extreme low pH in the present range of variability, may reach its limit in increasingly extreme environments under natural conditions.
'Is Insulin Right for Me?' Development of a theory-informed, web-based resource for reducing psychological barriers to insulin therapy in type 2 diabetes.
Creators: name: Holloway, Edith E
name: Speight, Jane
name: Furler, John
name: Hagger, Virginia
name: O'Neal, David N
name: Skinner, Timothy
name: Holmes-Truscott, Elizabeth
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: OBJECTIVE: To develop a theory and evidence-based web intervention to reduce psychological barriers towards insulin therapy among adults with non-insulin-treated type 2 diabetes (T2D). METHODS: Salient psychological barriers towards insulin were identified from the literature and classified using the Theoretical Domains Framework (TDF). Relevant TDF domains were mapped to evidence-based behaviour change techniques (BCTs), which informed the content for each barrier. Acceptability was explored using cognitive debriefing interviews (n=6 adults with T2D). RESULTS: 'Is Insulin Right for Me' addresses eight barriers, phrased as common questions: Does insulin mean my diabetes is more serious? Do insulin injections cause complications? Is it my fault I need to inject insulin? Will I gain weight? Will injecting hurt? What about hypos? Will injecting insulin be a burden? What will others think of me? BCTs, including persuasive communication and modelling/demonstration, were delivered using appropriate methods (eg, demonstration of the injection process). Participant suggestions for improvement included clear and direct messages, normalising insulin and avoiding confronting images. CONCLUSIONS: 'Is Insulin Right for Me' is the first theory and evidence-based, web intervention designed to reduce psychological barriers towards insulin therapy for adults with T2D. Evaluation is needed to determine its impact on negative appraisals and receptiveness towards insulin.
Additional file 1 of Targeting SOST using a small-molecule compound retards breast cancer bone metastasis
Creators: name: Sun, Lisha
name: Zhang, Yixiao
name: Chen, Guanglei
name: Ji, Yaoting
name: Ma, Qingtian
name: Qiao, Xinbo
name: Wu, Sijin
name: Zhou, Lin
name: Bu, Jiawen
name: Zhu, Xudong
name: Zhang, Xiaoying
name: Jiang, Xiaofan
name: Liu, Chao
name: Li, Xinnan
name: Liu, Yang
name: Yang, Yongliang
name: Liu, Caigang
Publisher: name: figshare
Year: 2024
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1: Fig. S1. Survival analysis of SOST expression in different subgroups of breast cancer patients. Fig. S2. SOST knockdown inhibits the proliferation and migration of SCP2 cells in vitro. Fig. S3. Correlation analysis of STAT3 expression with RAS and TGF-β/SMADs. Fig. S4. BLI analysis of 35 small-molecule compounds targeting SOST, except for 3 insoluble small-molecule compounds. Fig. S5. Other candidates that targeting SOST protein. Fig. S6. The cytotoxicity of S6 compound against breast cancer cells. Fig. S7. The safety profile of S6 in the vital organs of tumor-bearing mice. Table S1. Single concentration screening of small-molecules. Table S2. The results of the multi-concentration gradient assays were calculated.
Socio-demographic, clinical and service use determinants associated with HIV related stigma among people living with HIV/AIDS: a systematic review and meta-analysis
Creators: name: Armoon, B
name: Higgs, Peter
name: Fleury, MJ
name: Bayat, AH
name: Moghaddam, LF
name: Bayani, A
name: Fakhri, Y
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Background: Defining HIV-related stigma (HRS) can be problematic due to structural inequalities, cultural differences, discrimination by health care providers and the limitations of tools measuring stigma for people living with HIV (PLWH). This meta-analysis aimed to determine self-reported HRS and its association with socio-demographic and clinical determinants. Methods: PubMed, Scopus, Web of Science, PsycInfo, SciELO and Cochrane electronic databases were searched and after reviewing for study duplicates, the full-text of selected articles were assessed for eligibility using Population, Intervention, Comparator, Outcomes criteria. We used fixed and random-effects meta-analysis models to estimate the pooled prevalence, pooled odds ratio (OR) and 95% confidence intervals. Results: Thirty-one studies containing 10,475 participants met the eligibility criteria. Among the potential risk factors: age > 30 years (OR = 0.93, 95%CI = 0.86, 1), living with a spouse (OR = 0.07, 95%CI = 0.02, 0.17), CD4 count < 200 (OR = 0.5, 95% CI = 0.31, 0.68), medication adherence (OR = 0.96, 95%CI = 0.94, 0.99), poor access to care (OR = 0.79, 95%CI = 0.65, 0.93), time since diagnosis, and accessibility to care (OR = 0.37, 95%CI = 0.11, 0.86) were all significantly associated with self-reported HIV stigma among PWLH. Conclusion: Stigma is correlated with numerous negative consequences in marginalised populations including PLWH. Considering the negative association that stigma has on HIV prevention and treatment targeted evidence-based stigma reduction interventions are recommended. Interventions that are focused on a particular group, such as healthcare professionals are warranted. Rigorously designed studies with specific and validated outcome measures associated with targeted interventions may help to improve the reduction of HRS for PLWH.
Table_S4 – Supplemental material for Moral distress and moral competences in midwifery: A latent variable approach
Creators: name: Oelhafen, Stephan
name: Cignacco, Eva
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: FOS: Clinical medicine
subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental material, Table_S4 for Moral distress and moral competences in midwifery: A latent variable approach by Stephan Oelhafen and Eva Cignacco in Journal of Health Psychology
Local knowledge, utilisation and consumption of seaweed in coastal communities of southwestern Madagascar
Creators: name: Rodine, C
name: Rakotoarimanana, A
name: Ramamonjisoa, AB
name: Ranivoarivelo, LN
name: Rakotomahazo, C
name: Todinanahary, GBG
name: Tsiresy, G
name: Jaonalison, H
name: Nomenisoa, AL
name: Eeckhaut, I
name: Remanevy, ME
name: Obe, JS
name: Rasolofonirina, R
name: Lavitra, T
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy
subject: Plant Biology

description: This study explored the local knowledge, utilisation and consumption of seaweeds (lomotsy in Malagasy) among coastal communities in southwestern Madagascar. Primary data were collected in eight villages, through a survey questionnaire (with a total of 629 respondents) and daily focus group discussions, conducted between May and December 2022. The findings reveal widespread familiarity with seaweed, used predominantly for farming, cleaning fishing equipment, and shading fish during transport. A smaller proportion of respondents (9%) had experimented with seaweed as a food source, notably incorporating species like Kappaphycus alvarezii and Hydroclathrus clathratus into soups and sauces. Despite the coastal inhabitants’ recognition of seaweed, the potential of the seaweed resource has not been fully developed, with utilisation restricted mainly to limited traditional practices. An interest in incorporating seaweed into a person’s future diet or in seaweed cultivation was expressed by 58% and 45% of the respondents, respectively. This study underscores the importance of enhanced and sustainable use of the seaweed resource in Madagascar’s coastal communities, presenting opportunities for economic development and ecological conservation.
Key Factors in Knowledge Management of Higher Education Schools
Creators: name: Hsieh, Hsin-Ming
name: Maritz, Alex
Publisher: name: La Trobe
Year: 2021
Subjects: classificationCode: 3507
subject: Strategy, management and organisational behaviour

description: https://www.ijoi-online.org/index.php/current-issue/337-key-factors-in-knowledge-management-of-higher-education-schools
Abstract: Quality education is one of the most important and effective ways to promote national competitiveness. Schools are education-oriented places, but the major resource is knowledge that teachers’ effective knowledge management is related to the future development of schools. Being the first-line personnel in education, teachers are facing the role of education, students, and working for knowledge delivery. Knowledge management would not simply affect students’ learning outcomes but also the effectiveness of running a school. Targeting higher education schools in the south of Taiwan, teachers and administrative staff were distributed 300 copies of a questionnaire usung with random sampling techniques. A total of 223 valid copies were retrieved, with the retrieval rate 74%. Based on the research results, suggestions are proposed, assisting higher education teachers present good knowledge management ability and promote teaching quality to make students’ learning more effective and benefit the promotion of school effectiveness.
Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?
Creators: name: Barrios, Marilou H
name: Garnham, Alexandra L
name: Foers, Andrew D
name: Sim, Lesley
name: Masters, Seth L
name: Pang, Ken C
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3102
subject: Bioinformatics and computational biology
classificationCode: 3214
subject: Pharmacology and pharmaceutical sciences
classificationCode: 3404
subject: Medicinal and biomolecular chemistry

description: Small extracellular vesicles (SEVs) such as exosomes are released by multiple cell types. Originally believed to be a mechanism for selectively removing unwanted cellular components, SEVs have received increased attention in recent years for their ability to mediate intercellular communication. Apart from proteins and lipids, SEVs contain RNAs, but how RNAs are selectively loaded into SEVs remains poorly understood. To address this question, we profiled SEV RNAs from mouse dendritic cells using RNA-Seq and identified a long noncoding RNA of retroviral origin, VL30, which is highly enriched (>200-fold) in SEVs compared to parental cells. Bioinformatic analysis revealed that exosome-enriched isoforms of VL30 RNA contain a repetitive 26-nucleotide motif. This repeated motif is itself efficiently incorporated into SEVs, suggesting the likelihood that it directly promotes SEV loading. RNA folding analyses indicate that the motif is likely to form a long double-stranded RNA hairpin and, consistent with this, its overexpression was associated with induction of a potent type I interferon response. Taken together, we propose that preferential loading into SEVs of the VL30 RNA containing this immunostimulatory motif enables cells to remove a potentially toxic RNA and avoid autoinflammation. In this way, the original notion of SEVs as a cellular garbage bin should not be entirely discounted.
Additional file 1 of The company we keep. Using hemodialysis social network data to classify patients’ kidney transplant attitudes with machine learning algorithms
Creators: name: Aljurbua, Rafaa
name: Gillespie, Avrum
name: Obradovic, Zoran
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Biological Sciences not elsewhere classified
Marine Biology
Cancer
Science Policy

description: Additional file 1: Figure S1. Inclusion and Enrollment in the Study. Table S1. Demographic Differences Between Facility 1 and 2. Table S2. Age and Sex Differences Between Participants and Non-Participants. (SD) standard deviation. Figure S2. Comparing Sociodemographic to Network Variables using Logistic Regression, Support Vector Machine, and Neural Network Models Machine Learning Models including isolates. Sociodemographicvariables included age, sex, Black race, marital status, education, employment status, self-reported health, dialysis vintage, whether they would accept a living donation, and whether they would accept a deceased donation. The network variables included degree centrality, eigenvector centrality, closeness centrality, betweenness centrality, and clustering. The accuracy, precision, recall, and F1-score are the mean of the of running the model five times. They are reported as percentages. The variation of the running the five models are reported in parentheses. Table S3. Comparing Sociodemographic to Network Variables using Logistic Regression, Support Vector Machine, and Neural Network Models. Table S4. Performance of Machine Learning Algorithm when Data from Only One Facility is Used.
Supplementary_Material_I – Supplemental material for Disaffection and agentic engagement: ‘Redesigning’ activities to enable authentic self-expression
Creators: name: Henry, Alastair
name: Thorsen, Cecilia
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Education
subject: 200399 Language Studies not elsewhere classified
subject: FOS: Languages and literature

description: Supplemental material, Supplementary_Material_I for Disaffection and agentic engagement: ‘Redesigning’ activities to enable authentic self-expression by Alastair Henry and Cecilia Thorsen in Language Teaching Research
Supplemental material for Screening of the cervical spine in subacromial shoulder pain: A systematic review
Creators: name: Walker, Tom
name: Salt, Emma
name: Lynch, Greg
name: Littlewood, Chris
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material for Screening of the cervical spine in subacromial shoulder pain: A systematic review by Tom Walker, Emma Salt, Greg Lynch and Chris Littlewood in Shoulder & Elbow
Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?
Creators: name: Barrios, Marilou H
name: Garnham, Alexandra L
name: Foers, Andrew D
name: Cheng-Sim, Lesley
name: Masters, Seth L
name: Pang, Ken C
Publisher: name: La Trobe
Year: 2021

description: Small extracellular vesicles (SEVs) such as exosomes are released by multiple cell types. Originally believed to be a mechanism for selectively removing unwanted cellular components, SEVs have received increased attention in recent years for their ability to mediate intercellular communication. Apart from proteins and lipids, SEVs contain RNAs, but how RNAs are selectively loaded into SEVs remains poorly understood. To address this question, we profiled SEV RNAs from mouse dendritic cells using RNA-Seq and identified a long noncoding RNA of retroviral origin, VL30, which is highly enriched (>200-fold) in SEVs compared to parental cells. Bioinformatic analysis revealed that exosome-enriched isoforms of VL30 RNA contain a repetitive 26-nucleotide motif. This repeated motif is itself efficiently incorporated into SEVs, suggesting the likelihood that it directly promotes SEV loading. RNA folding analyses indicate that the motif is likely to form a long double-stranded RNA hairpin and, consistent with this, its overexpression was associated with induction of a potent type I interferon response. Taken together, we propose that preferential loading into SEVs of the VL30 RNA containing this immunostimulatory motif enables cells to remove a potentially toxic RNA and avoid autoinflammation. In this way, the original notion of SEVs as a cellular garbage bin should not be entirely discounted.
Postcolonial frameworks with survivors’ voices: Teaching about contemporary and historical forms of slavery and forced labour
Creators: name: Yea, Sallie
Publisher: name: La Trobe
Year: 2021
Subjects: Uncategorized

description: Much of the information for educating students and the public about human trafficking only involves survivors’ direct experiences as brief excerpts from more complex and detailed narratives. In this paper, I draw on a postcolonial framework to argue that sidelining survivors’ voices can bolster anti-slavery stakeholders’ agendas by selectively using survivors’ narratives to illustrate narrow constructions of slavery and forced labour. As part of education and awareness efforts, such approaches to understanding slavery and forced labour also perpetuate stereotypes that trafficked persons are powerless and lack agency. Therefore, I present an alternative educational approach to remedy these tendencies by viewing and discussing narratives by, and about, trafficked persons. This paper uses a university-level humanities and social science subject on trafficking and slavery, and related assessment tasks, as a case study to demonstrate the potential of survivors’ voices in teaching about slavery.
dvdres-feb-2018-00028-File003 – Supplemental material for Guidelines and clinical practice at the primary level of healthcare in patients with type 2 diabetes mellitus with and without kidney disease in five European countries
Creators: name: Eder, Susanne
name: Leierer, Johannes
name: Kerschbaum, Julia
name: Laszlo Rosivall
name: Wiecek, Andrzej
name: Zeeuw, Dick De
name: Mark, Patrick B
name: Heinze, Georg
name: Rossing, Peter
name: Hiddo L Heerspink
name: Mayer, Gert
Publisher: name: SAGE Journals
Year: 2018
Subjects: subject: Cardiology
subject: 110306 Endocrinology
subject: FOS: Clinical medicine
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, dvdres-feb-2018-00028-File003 for Guidelines and clinical practice at the primary level of healthcare in patients with type 2 diabetes mellitus with and without kidney disease in five European countries by Susanne Eder, Johannes Leierer, Julia Kerschbaum, Laszlo Rosivall, Andrzej Wiecek, Dick de Zeeuw, Patrick B Mark, Georg Heinze, Peter Rossing, Hiddo L Heerspink and Gert Mayer in Diabetes & Vascular Disease Research