cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
An Improved Standard Model Prediction Of BR(B -> tau nu) And Its Implications For New Physics
Creators: name: UTfit Collaboration
name: Bona, M.
name: Ciuchini, M.
name: Franco, E.
name: Lubicz, V.
name: Martinelli, G.
name: Parodi, F.
name: Pierini, M.
name: Schiavi, C.
name: Silvestrini, L.
name: Sordini, V.
name: Stocchi, A.
name: Tarantino, C.
name: Vagnoni, V.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The recently measured B -> tau nu branching ratio allows to test the Standard Model by probing virtual effects of new heavy particles, such as a charged Higgs boson. The accuracy of the test is currently limited by the experimental error on BR(B -> tau nu) and by the uncertainty on the parameters fB and |Vub|. The redundancy of the Unitarity Triangle fit allows to reduce the error on these parameters and thus to perform a more precise test of the Standard Model. Using the current experimental inputs, we obtain BR(B -> tau nu)_SM = (0.84 +- 0.11)x10^{-4}, to be compared with BR(B -> tau nu)_exp = (1.73 +- 0.34)x10^{-4}. The Standard Model prediction can be modified by New Physics effects in the decay amplitude as well as in the Unitarity Triangle fit. We discuss how to disentangle the two possible contributions in the case of minimal flavour violation at large tan beta and generic loop-mediated New Physics. We also consider two specific models with minimal flavour violation: the Type-II Two Higgs Doublet Model and the Minimal Supersymmetric Standard Model.
description: 7 pages, 13 figures, 1 table. v2: added references and discussion of B -> D tau nu in the 2HDM. v3: added Bs->mumu in the 2HDM. Final version to appear in PLB
Generation Victoria (GenV) Cohort 2020s Protocol
Creators: name: Wake, Melissa
name: GOLDFELD, SHARON
name: Saffery, Richard
name: Siero, William
name: Hughes, Elizabeth
Publisher: name: Murdoch Childrens Research Institute
Year: 2021
Subjects: Health Sciences
Biological Sciences
Social Science

description: The Generation Victoria (GenV) Cohort 2020s Protocol covers conduct of the state-wide GenV project from 2021-2023. It outlines the project design, recruitment approach, data collection, risk, data & biosample management and operational details. This protocol is version 3.1 (dated 29/07/2021) and was approved by the Royal Children's Hospital Human Research and Ethics Committee on 17/08/2021.

 We would like to acknowledge the following people for their contributions: Members of the GenV Investigator Committee, Focus Area and Method Cores Working Groups, and GenV team.
Generation Victoria (GenV) Cohort 2020s Participant Information Statement and Consent Form
Creators: name: Wake, Melissa
name: GOLDFELD, SHARON
name: Saffery, Richard
name: Siero, William
name: Hughes, Elizabeth
Publisher: name: Murdoch Childrens Research Institute
Year: 2021
Subjects: Health Sciences
Biological Sciences
Social Science

description: The Generation Victoria (GenV) Cohort 2020s Participant Information Statement and Consent Form comprises an 6-page information statement of the purpose, methods, demands, risks and potential benefits of GenV, and a 2-page consent form for completion by parents/guardians. This is version 2 of the GenV state-wide PICF (dated 15/06/21) and was approved by the Royal Children's Hospital Human Research Ethics Committee on 06/07/2021.
 We would like to acknowledge the following people for their contributions: Members of the GenV Investigator Committee, Focus Area and Method Cores Working Groups, and GenV team.
Dark Matter Particle Spectroscopy at the LHC: Generalizing MT2 to Asymmetric Event Topologies
Creators: name: Konar, Partha
name: Kong, Kyoungchul
name: Matchev, Konstantin T.
name: Park, Myeonghun
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We consider SUSY-like missing energy events at hadron colliders and critically examine the common assumption that the missing energy is the result of two identical missing particles. In order to experimentally test this hypothesis, we generalize the subsystem MT2 variable to the case of asymmetric event topologies, where the two SUSY decay chains terminate in different "children" particles. In this more general approach, the endpoint MT2max of the MT2 distribution now gives the mass Mp(Mc(a),Mc(b)) of the parent particle as a function of two input children masses Mc(a) and Mc(b). We propose two methods for an independent determination of the individual children masses Mc(a) and Mc(b). First, in the presence of upstream transverse momentum P(UTM) the corresponding function Mp(Mc(a),Mc(b),P(UTM)) is independent of P(UTM) at precisely the right values of the children masses. Second, the previously discussed MT2 "kink" is now generalized to a "ridge" on the 2-dimensional surface Mp(Mc(a),Mc(b)). As we show in several examples, quite often there is a special point along that ridge which marks the true values of the children masses. Our results allow collider experiments to probe a multi-component dark matter sector directly and without any theoretical prejudice.
description: 50 pages, 31 figures, includes a new Appendix, references added, typos corrected
Additional file 1: of Urinary angiostatin: a novel biomarker of kidney disease associated with disease severity and progression
Creators: name: Xia, Yuan-Yuan
name: Bu, Ru
name: Cai, Guang-Yan
name: Zhang, Xue-Guang
name: Duan, Shu-Wei
name: Wu, Jie
name: Wu, Di
name: Chen, Xiang-Mei
Publisher: name: figshare
Year: 2019
Subjects: subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Table S1. Demographics and clinical characteristics of patients in the IgAN group. Table S2. Clinical characteristics of healthy subjects. Table S3. Leeâ s grade and Oxford Classification scores characteristics of patients in the IgAN group. Table S4. Demographics and clinical characteristics of patients in the matched IgAN group and DC controls. (DOCX 16 kb)
Triple Combination Formulation for Treatment of Chronic Pain.
Creators: name: Apkarian, A. Vania
name: Halder, Kasturi
name: Centeno, Maria Virginia
name: Alam, Suhail
Publisher: name: University of Notre Dame
Year: 2023

description: The disclosure relates to use of a triple formulation comprising a histone deacytlase, a cyclodextrin and polyethylene glycol or propylene glycol, and in the treatment and management of chronic pain.
Maxwell's equations on the $κ$-Minkowski spacetime and Electric-Magnetic duality
Creators: name: Harikumar, E.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive the Maxwell's equations on the $κ$-deformed spacetime, valid up to first order in the deformation parameter, using the Feynman's approach. We show that the electric-magnetic duality is a symmetry of these equations. It is also shown that the laws of electrodynamics are {\it different} for particles of equal charges, but with different masses. We show that the Poincare angular momentum, required to maintain the usual Lorentz algebra structure, do not get any $κ$-dependent corrections.
description: 7 pages, Typos corrected,changes made for clarity, removed a sentence, to appear in Europhysics Letters
Cordilleran geochronology deduced from hydrothermal leads
Creators: name: Small, William David
Publisher: name: University of British Columbia
Year: 2011

description: A total of 34 lead ore samples from selected hydrothermal deposits in Wyoming, Montana, and Idaho have been isotopically analyzed and geochronological interpretations made from the results. Leads from along the southeastern flank of the Idaho Batholith appear to have a primary component 2500 my old. Leads from Butte and Cassia counties, Idaho, may be interpreted as having this same primary component with an added component that is estimated to be 1400 to 1600 my old. The radiogenic component of leads along the southeastern flank of the Idaho Batholith commenced development in a closed system 2500 my ago. Radiogenic components of the leads from Butte and Cassia counties commenced development 1900 and 2700 my ago respectively. Preliminary results of analyses from the south end of the Wind River Mtns, Wyoming, and the Little Belt Mtns, Montana, show primary lead ages of about 3200 and 2200 my respectively. Common lead geochronology indicates that the basement rocks of Southern Idaho may be assigned to the Superior Province of North America as defined by Kanasewich (1965). A second Precambrian event was recorded by a change in the lead isotope abundances during the Penokian era. Thus, Southern Idaho had been subjected to several uplifts during parts of Early and Middle Precambrian time. The ages of the anomalous leads from Butte and Cassia counties could represent the times of formation of sedimentary layers which remained closed systems until the time of formation of the ore bodies. A model for continental accretion and growth is discussed. The contribution of the present report to tectonic development models is in the suggestion of a geological sequence which may give rise to anomalous lead suites. This geological sequence is concerned with regional tectonic events which take place in the lower crust and are manifested by igneous activity. Examples of leads with apparent enrichment in the 208 isotope were found during this study and other instances are mentioned. The enrichment is tentatively considered to occur as a result of concentration of the thorium decay product in sedimentary basins. This could occur if the thorium is in more easily weathered minerals than are the uranium isotopes. Evidence supporting naturally occurring lead isotope enrichment phenomena is cited.
Вопросы устойчивого развития общества,Выпуск 13 МКРНП 2022
Creators: name: ООО "Институт развития образования и консалтинга"
Publisher: name: ООО "Институт развития образования и консалтинга"
Year: 2022

description: Вопросы устойчивого развития общества,Выпуск 13 МКРНП 2022
Unsterile-Active Neutrino Mixing: Consequences on Radiative Decay and Bounds from the X-ray Background
Creators: name: Boyanovsky, D.
name: Holman, R.
name: Hutasoit, Jimmy A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider a sterile neutrino to be an unparticle, namely an \emph{unsterile neutrino}, with anomalous dimension $η$ and study its mixing with a canonical active neutrino via a see-saw mass matrix. We show that there is \emph{no unitary} transformation that diagonalizes the mixed propagator and a field redefinition is required. The propagating or ``mass'' states correspond to an unsterile-like and active-like mode. The unsterile mode features a complex pole or resonance for $0 \leq η< 1/3$ with an ``invisible width'' which is the result of the decay of the unsterile mode into the active mode and the massless particles of the hidden conformal sector. For $η\geq 1/3$, the complex pole disappears, merging with the unparticle threshold. The active mode is described by a stable pole, but ``inherits'' a non-vanishing spectral density above the unparticle threshold as a consequence of the mixing. We find that the \emph{radiative} decay width of the unsterile neutrino into the active neutrino (and a photon) via charged current loops, is \emph{suppressed} by a factor $\sim \Big[2 \sin^2(θ_0) \frac{M^2}{Λ^2}\Big]^\fracη{1-η}$, where $θ_0$ is the mixing angle for $η=0$, $M$ is approximately the mass of the unsterile neutrino and $Λ\gg M$ is the unparticle-scale. The suppression of the radiative (visible) decay width of the sterile neutrino weakens the bound on the mass and mixing angle from the X-ray or soft gamma-ray background.
description: 30 pages, 6 figures; v.2 typos corrected and references added
ReCycle: Resilient Training of Large DNNs using Pipeline Adaptation
Creators: name: Gandhi, Swapnil
name: Zhao, Mark
name: Skiadopoulos, Athinagoras
name: Kozyrakis, Christos
Publisher: name: arXiv
Year: 2024
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Training large Deep Neural Network (DNN) models requires thousands of GPUs over the course of several days or weeks. At this scale, failures are frequent and can have a big impact on training throughput. Utilizing spare GPU servers to mitigate performance loss becomes increasingly costly as model sizes grow. ReCycle is a system designed for efficient DNN training in the presence of failures, without relying on spare servers. It exploits the inherent functional redundancy in distributed training systems -- where servers across data-parallel groups store the same model parameters -- and pipeline schedule bubbles within each data-parallel group. When servers fails, ReCycle dynamically re-routes micro-batches to data-parallel peers, allowing for uninterrupted training despite multiple failures. However, this re-routing can create imbalances across pipeline stages, leading to reduced training throughput. To address this, ReCycle introduces two key optimizations that ensure re-routed micro-batches are processed within the original pipeline schedule's bubbles. First, it decouples the backward pass into two phases: one for computing gradients for the input and another for calculating gradients for the parameters. Second, it avoids synchronization across pipeline stages by staggering the optimizer step. Together, these optimizations enable adaptive pipeline schedules that minimize or even eliminate training throughput degradation during failures. We describe a prototype for ReCycle and show that it achieves high training throughput under multiple failures, outperforming recent proposals for fault-tolerant training such as Oobleck and Bamboo by up to $1.46\times$ and $1.64\times$, respectively.
description: SOSP'24 | Camera-Ready
Consistent Thermodynamics for Quasiparticle Boson System with Zero Chemical Potential
Creators: name: Yin, Shaoyu
name: Su, Ru-Keng
Publisher: name: arXiv
Year: 2008
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The thermodynamic consistency of quasiparticle boson system with effective mass $m^*$ and zero chemical potential is studied. We take the quasiparticle gluon plasma model as a toy model. The failure of previous treatments based on traditional partial derivative is addressed. We show that a consistent thermodynamic treatment can be applied to such boson system provided that a new degree of freedom $m^*$ is introduced in the partial derivative calculation. A pressure modification term different from the vacuum contribution is derived based on the new independent variable $m^*$. A complete and self-consistent thermodynamic treatment for quasiparticle system, which can be widely applied to effective mass models, has been constructed.
description: 21 pages, 10 figures (the description to the model is modified, accepted by Int.J.Mod.Phys.A)
K[40] - Ar[40] isotopic age determination of the Nelson batholith, B.C.
Creators: name: Nguyeh, Kim-Khanh
Publisher: name: University of British Columbia
Year: 2011

description: The purposes of this thesis are to examine ages of the Nelson batholith and its satellites because of the wide range of biotite model ages previously published in the literature, and to test hornblende and pyroxene further for their application in K⁴⁰ - Ar⁴⁰ dating as reliable minerals. K⁴⁰ - Ar⁴⁰ model ages obtained on biotite, hornblende and clinopyroxene from the present study indicate with certainty that the various phases of the Nelson batholith were emplaced during a short span of time, centered around 156 m.y. corresponding to the Upper-Middle Jurassic boundary of the Kulp’s time scale. At least a period of hydrothermal alteration has occurred in this area since that time. It is evident that these phases cannot be distinguished on the basis of their K⁴⁰ - Ar⁴⁰ model ages. It is also evident that hornblende gives reliable model ages. Clinopyroxene contains significant excess of radiogenic argon and should not be used for K⁴⁰ - Ar⁴⁰ dating. Biotite may occasionally contain excess of radiogenic argon, particularly under high temperature and high argon pressure environmental conditions. Analytical techniques used and descriptions of the samples analyzed are given as appendixes.
Giant graviton expansions and ETW brane
Creators: name: Hatsuda, Yasuyuki
name: Lin, Hai
name: Okazaki, Tadashi
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the giant gravitons in the $AdS_4$ bagpipe geometries involving end-of-the-world (ETW) brane constructed by a single $5$-brane and either two stacks or one stack of D3-branes in Type IIB string theory. From the exact formulae and giant graviton expansions of the half-indices for the half-BPS boundary conditions and interfaces in $\mathcal{N}=4$ super Yang-Mills theory, we obtain the BPS spectra of the fluctuation modes of the $AdS_4$ bagpipe geometries including the ETW brane region.
description: 38 pages, 2 figures, v2: published version in JHEP
Couplings in coupled channels versus wave functions: application to the X(3872) resonance
Creators: name: Gamermann, D.
name: Nieves, J.
name: Oset, E.
name: Arriola, E. Ruiz
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We perform an analytical study of the scattering matrix and bound states in problems with many physical coupled channels. We establish the relationship of the couplings of the states to the different channels, obtained from the residues of the scattering matrix at the poles, with the wave functions for the different channels. The couplings basically reflect the value of the wave functions around the origin in coordinate space. In the concrete case of the X(3872) resonance, understood as a bound state of $\ddn$ and $\ddc$ (and $c.c.$), with the $\ddn$ loosely bound, we find that the couplings to the two channels are essentially equal leading to a state of good isospin I=0 character. This is in spite of having a probability for finding the $\ddn$ state much larger than for $\ddc$ since the loosely bound channel extends further in space. The analytical results, obtained with exact solutions of the Schrödinger equation for the wave functions, can be useful in general to interpret results found numerically in the study of problems with unitary coupled channels methods.
description: 14 pages, 4 figures
Collaborating with nature: Reinterpreting human ecology
Creators: name: Chatwin, DA
Publisher: name: University Of Tasmania
Year: 2023

description: This project investigates visual strategies for representing human ecology; the study of interrelationships between people and their environment. Motivated by the numerous human induced environmental issues confronting contemporary society, this research develops poetic reinterpretations of human ecology through metaphor, allusion and symbolism. The artworks operate in collaboration with nature, revealing hidden or obscured connections between artificial and natural elements to emphasise the inclusive relationship between society and nature. This strategy intentionally contrasts the often didactic and sensationalistic methodologies employed by scientific and governmental institutions in specific relation to environmental issues. The development of the project is informed by Lucy Lippard's ideas relating to personal narrative and how this contributes to the transformation of anonymous 'space' into a familiar 'place'. Miwon Kwon's concept of the discursive site has motivated the creation of aesthetic strategies specifically directed towards prompting viewers to reconsider familiar ecological exchanges. This aspect of the project, supported by principles drawn from the field of ecological aesthetics, has facilitated the development of works embodying connections between society and nature. Artistic responses consist of three distinct formal approaches: sculpture; site-specific installation; and multi-image digital projection. The sculptures juxtapose natural and artificial materials to reference and explore nature/culture interrelationships and processes. The site-specific installations further develop these ideas by directly engaging in situ features in order to reinterpret the operation of a local ecosystem. These installations also explore the interfaces between artificial and natural features in areas analogous to the peri-urban zone; locations where ecological complexity creates a particularly dynamic environment. The suite of digital work represents interactions between natural elements, the artist's home, and the artist, as a means to evaluate the potential for a personal human ecology to contribute to a broader environmental discourse. These three divergent formal methodologies facilitate an assessment of their respective potential to embody and convey ecological considerations to viewers. From this experience it is possible to identify the distinct characteristics and advantages in directly engaging features via interventions sited at the natural/artificial interface where the actual lived context provided by these in situ exchanges generates projects that reveal localised interaction's potential for prosaic ecological exploration. This research also contextualises the domestic environment as the basis for generating rich, novel and socially relevant ecological reinterpretations. In combination these phenomena contribute to the discourse relating to nature, culture and human ecology.
title: Résistance des bâtiments à l'incendie
Creators: name: Shorter, G. W.
Publisher: name: Conseil national de recherches du Canada. Division des recherches en construction
Year: 1967
Subjects: subject: Performance of:
valueUri: urn:ircsubjects:IRC0480
subject: Tenue
valueUri: urn:ircsubjects:IRC0480
subject: fire resistance
subject: résistance au feu
subject: fire resistance tests
subject: essai de résistance au feu
subject: test rooms
subject: salle conditionnée (essai)
subject: building functional elements
subject: élément d'ouvrage

description: Ce Digeste traite des essais de résistance au feu, les installations d'essai de résistance au feu, et les exigences du Code national du bâtiment (1960) relativement à la résistance au feu.
title: Fire endurance of building constructions
Creators: name: Shorter, G. W.
Publisher: name: National Research Council of Canada. Division of Building Research
Year: 1964
Subjects: subject: Performance of:
valueUri: urn:ircsubjects:IRC0480
subject: Tenue
valueUri: urn:ircsubjects:IRC0480
subject: fire resistance
subject: résistance au feu
subject: fire resistance tests
subject: essai de résistance au feu
subject: test rooms
subject: salle conditionnée (essai)
subject: building functional elements
subject: élément d'ouvrage

description: This digest discusses fire resistance tests and test facilities, and the National Building Code (1960) fire resistance requirements.
Social skills and theory of mind in children with traumatic brain injury
Creators: name: Paine, S
Publisher: name: University Of Tasmania
Year: 2023

description: This thesis investigated the social competencies of children with traumatic brain injury (TBI) by investigating the predictors of social functioning and developing a measure of affective theory of mind (ToM). Study 1 examined the biopsychosocial predictors of social functioning in 56 children (7 - 16 years) with TBI. Using Beauchamp and Anderson's (2010) socio-cognitive integration of abilities (SOCIAL) model, the study investigated the predictive abilities of family functioning, socio-economic status, children's internal behaviours, executive functions, communication and social-cognitive abilities. A series of hierarchical multiple regression analyses showed that family functioning, internal behaviours, ecological executive functions and ToM made significant unique and collective contributions to the prediction of children's socialisation skills and social behaviours. In light of the importance ToM has on children's social functioning, Study 2 developed a measure of affective ToM and trialled its use on 17 children with TBI and a control group of 59 typically developing children (4 ‚Äö- 6.5 years). A visual and verbal version of a story book was developed to ask children a series of factual and emotional questions which were designed to assess their understanding of others' feelings during social interactions. A series of analyses of variance were run, controlling for children's receptive language skills. Although there was no significant difference between children with TBI and typically developing children on the factual and emotional questions, the results showed that children correctly answered significantly more emotional questions when the story was conveyed verbally as opposed to visually. There was no significant difference between book types on the fact questions. Furthermore, the results showed that affective ToM is a skill that develops with age, particularly during the preschool years. Both Study 1 and 2 have implications for the development of social rehabilitation techniques in children with TBI. In particular, Study 1 highlights the importance of family therapy and rehabilitation that targets children's mood and understanding of others' beliefs. Study 2 built on the concept of addressing ToM, and the findings have implications for teaching children about emotions and highlight the importance of language.
Crystal structure of (1S, 2R,4S)-1-((phenylamino)methyl)-4-(prop-1-en-2-yl) cyclohexane-1,2-diol), C16H23NO2
Creators: name: Outouch, R.
name: Boualy, B.
name: El Firdoussi, L.
name: Ali, M.A.
name: Rizzoli, C.
name: Spannenberg, A.
Publisher: name: Heidelberg : Springer
Year: 2011
Subjects: subject: chemistry
subject: crystal structure
subject: crystallography
subject: 540

description: C16H23NO2, orthorhombic, P2 12121 (no. 19), a = 5.9637(3) Å, b = 8.8317(5) Å, c = 27.809(1) Å, V = 1464.7 Å3, Z = 4, Rgt(F) = 0.026, wRref(F2) = 0.040, T= 150 K.
The cause of oscillations of the large-scale circulation of turbulent Rayleigh-B{é}nard convection
Creators: name: Brown, Eric
name: Ahlers, Guenter
Publisher: name: arXiv
Year: 2009
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In agreement with a recent experimental discovery by Xia et. al. (2009), we also find a sloshing mode in experiments on the large-scale circulation (LSC) of turbulent Rayleigh-Benard convection in a cylindrical sample of aspect ratio one. The sloshing mode has the same frequency as the torsional oscillation discovered by Funfschilling and Ahlers (2004). We show that both modes can be described by an extension of a model developed previously [Brown and Ahlers (2008)] which consists of permitting a lateral displacement of the LSC circulation plane away from the vertical center line of the sample as well as a variation in displacements with height (such displacements had been excluded in the original model). Pressure gradients produced by the side wall of the container on average center the plane of the LSC so that it prefers to reach its longest diameter. If the LSC is displaced away from this diameter, the walls provide a restoring force. Turbulent fluctuations drive the LSC away from the central alignment, and combined with the restoring force they lead to oscillations. These oscillations are advected along with the LSC. This model predicts the correct wavenumber and phase of the oscillations, as well as estimates of the frequency, amplitude, and probability distributions of the displacements.
description: 16 pages, 6 figures, submitted to Journal of Fluid Mechanics
A Trifunctional Linker for Palmitoylation and Peptide and Protein Localization in Biological Membranes
Creators: name: Syga, Łukasz
name: De Vries, Reinder H.
name: Van Oosterhout, Hugo
name: Bartelds, Rianne
name: Boersma, Arnold J.
name: Roelfes, Gerard
name: Poolman, Bert
Publisher: name: Weinheim : Wiley-VCH
Year: 2020
Subjects: subject: lipid phase separation
subject: membrane partitioning
subject: palmitoylation
subject: trifunctional linker
subject: biological membranes
subject: 540

description: Attachment of lipophilic groups is an important post-translational modification of proteins, which involves the coupling of one or more anchors such as fatty acids, isoprenoids, phospholipids, or glycosylphosphatidyl inositols. To study its impact on the membrane partitioning of hydrophobic peptides or proteins, we designed a tyrosine-based trifunctional linker. The linker allows the facile incorporation of two different functionalities at a cysteine residue in a single step. We determined the effect of the lipid modification on the membrane partitioning of the synthetic α-helical model peptide WALP with or without here and in all cases below; palmitoyl groups in giant unilamellar vesicles that contain a liquid-ordered (Lo) and liquid-disordered (Ld) phase. Introduction of two palmitoyl groups did not alter the localization of the membrane peptides, nor did the membrane thickness or lipid composition. In all cases, the peptide was retained in the Ld phase. These data demonstrate that the Lo domain in model membranes is highly unfavorable for a single membrane-spanning peptide. © 2019 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.
Message-Passing Monte Carlo: Generating low-discrepancy point sets via Graph Neural Networks
Creators: name: Rusch, T. Konstantin
name: Kirk, Nathan
name: Bronstein, Michael M.
name: Lemieux, Christiane
name: Rus, Daniela
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Numerical Analysis (math.NA)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences
subject: FOS: Mathematics

description: Discrepancy is a well-known measure for the irregularity of the distribution of a point set. Point sets with small discrepancy are called low-discrepancy and are known to efficiently fill the space in a uniform manner. Low-discrepancy points play a central role in many problems in science and engineering, including numerical integration, computer vision, machine perception, computer graphics, machine learning, and simulation. In this work, we present the first machine learning approach to generate a new class of low-discrepancy point sets named Message-Passing Monte Carlo (MPMC) points. Motivated by the geometric nature of generating low-discrepancy point sets, we leverage tools from Geometric Deep Learning and base our model on Graph Neural Networks. We further provide an extension of our framework to higher dimensions, which flexibly allows the generation of custom-made points that emphasize the uniformity in specific dimensions that are primarily important for the particular problem at hand. Finally, we demonstrate that our proposed model achieves state-of-the-art performance superior to previous methods by a significant margin. In fact, MPMC points are empirically shown to be either optimal or near-optimal with respect to the discrepancy for low dimension and small number of points, i.e., for which the optimal discrepancy can be determined. Code for generating MPMC points can be found at https://github.com/tk-rusch/MPMC.
description: Published in Proceedings of the National Academy of Sciences (PNAS): https://www.pnas.org/doi/10.1073/pnas.2409913121
Entropy-Dominated Dissipation in Sapphire Shock-Compressed up to 400 GPa (4 Mbar)
Creators: name: Nellis, W. J.
name: Kanel, G. I.
name: Razorenov, S. V.
name: Savinykh, A. S.
name: Rajendran, A. M.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Sapphire (single-crystal Al2O3) is a representative Earth material and is used as a window and/or anvil in shock experiments. Pressure, for example, at the core-mantle boundary is about 130 gigapascals (GPa). Defects induced by 100-GPa shock waves cause sapphire to become opaque, which precludes measuring temperature with thermal radiance. We have measured wave profiles of sapphire crystals with several crystallographic orientations at shock pressures of 16, 23, and 86 GPa. At 23 GPa plastic-shock rise times are generally quite long (~100 ns) and their values depend sensitively on the direction of shock propagation in the crystal lattice. The long rise times are probably caused by the high strength of inter-atomic interactions in the ordered three-dimensional sapphire lattice. Our wave profiles and recent theoretical and laser-driven experimental results imply that sapphire disorders without significant shock heating up to about 400 GPa, above which Al2O3 is amorphous and must heat. This picture suggests that the characteristic shape of shock compression curves of many Earth materials at 100 GPa pressures is caused by a combination of entropy and temperature.
description: 12 pages, 4 figures
For poorer : how men experience, understand and respond to problematic aspects of a partner's gambling
Creators: name: Patford, J
Publisher: name: University Of Tasmania
Year: 2023

description: Gambling is now big business in Australia and public expenditure on gambling is high. While many people gamble within their means, some are unable to control the extent of their gambling and thus create difficulties, not only for themselves but for their marital or de facto partners. The present study aimed to explore the experiences, understandings and coping responses of men who had concerns about a partner's gambling. Various recruitment strategies were employed in an effort to attract a diverse group of participants. The final sample comprised thirteen men who had different attitudes and behaviours in regard to gambling and were in different types of relationship. Data were gathered by means of in-depth interviews and then subjected to thematic analysis. Findings from the study illuminate how these men became aware of their partner's gambling, their understandings regarding the causes of the gambling, the financial, psychological and social stressors they encountered as a result of the gambling and the coping strategies they deployed in order to minimize gambling-related harm. Overall, the findings indicate that men are not only the victims and enablers of a partner's problem gambling but sources of informal help and care. Implications for community education programs, formal services and Australian law are discussed.
Women MPs in Samoa and Kiribati
Creators: name: Baker, Kerryn
name: Shiu, Roannie Ng
name: Corbett, Jack
Publisher: name: Canberra, ACT : Coral Bell School of Asia Pacific Affairs, College of Asia and the Pacific, The Australian National University
Year: 2013

description: It is established that the percentage of women elected to parliament in the Pacific region is amongst the lowest in the world. In this paper the authors do not revisit debates about why this is the case, but identify a common profile of successful women MPs in the Pacific by looking at two countries where they have been relatively well represented — Samoa and Kiribati. In doing so, they identify a number of characteristics that do matter for women MPs.
Bydgostiana w zasobie Geheimes Staatsarchiv Preußischer Kulturbesitz w Berlinie (Dahlem) – uzupełnienie stanu wiedzy
Creators: name: Falkowski, Piotr
Publisher: name: Kronika Bydgoska
Year: 2023

description: Artykuł powstał na podstawie materiałów zgromadzonych w ramach wymiany archiwistów pomiędzy archiwami polskimi i niemieckimi. Autor tekstu był gościem w Geheimes Staatsarchiv Preußischer Kulturbesitz w Berlin (Dahlem), gdzie poszukiwał materiałów archiwalnych oraz publikacji traktujących o Bydgoszczy i regionie. W artykule zaprezentowano wyniki badań nad bydgostianami przechowywanymi w berlińskim archiwum. Opublikowanie informacji o bydgoskich archiwaliach zgromadzonych w zasobie GStA PK w Berlinie może przyczynić się do poszerzenia stanu wiedzy o dziejach miasta i regionu.
description: Kronika Bydgoska, Tom 44 (2023): Kronika Bydgoska
La numérisation des certificats d'origine au sein de la douane marocaine : opportunités, défis et enjeux
Creators: name: Younes BOUMAAZ
Publisher: name: Zenodo
Year: 2024

description: La numérisation des certificats d’origine revêt pour les administrations douanières une importance cruciale et peut dans ce cadre révolutionner les processus du commerce transfrontalier et les procédures règlementaires.

Pour sa part, la douane marocaine s’est engagée déjà depuis plusieurs années dans ce chantier de numérisation comme un projet pilote qui permet aux opérateurs de baisser les coûts de traitement de leurs opérations douanières et un allégement des formalités administratives.

À cet effet, la problématique dans ce papier de recherche est de débattre l’apport de la numérisation des certificats d’origine en matière douanière pour le cas de la douane marocaine.

Le présent travail analyse le problème étudié en examinant les opportunités, les défis ainsi que les enjeux, et enfin, en discutant des scénarios et des perspectives, en s’appuyant sur les résultats d’un benchmark entre les principaux systèmes de gestion des certificats d’origine.
Galaxy evolution from strong lensing statistics: the differential evolution of the velocity dispersion function in concord with the LambdaCDM paradigm
Creators: name: Chae, Kyu-Hyun
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We study galaxy evolution from z=1 to z=0 as a function of velocity dispersion sigma for galaxies with sigma > 95 km/s based on the measured and Monte Carlo realised local velocity dispersion functions (VDFs) of galaxies and the revised statistical properties of 30 strongly-lensed sources. We assume that the total (luminous plus dark) mass profile of a galaxy is isothermal in the optical region for 0 < z < 1 as suggested by mass modelling of lensing galaxies. For the evolutionary behaviours of the VDFs we find that: (1) the number density of massive (mostly early-type) galaxies with sigma > 200 km/s evolves differentially in the way that the number density evolution is greater at a higher velocity dispersion; (2) the number density of intermediate and low mass early-type galaxies (95 km/s < sigma < 200 km/s) is nearly constant; (3) the late-type VDF transformed from the Monte Carlo realised circular velocity function is consistent with no evolution in its shape or integrated number density consistent with galaxy survey results. These evolutionary behaviours of the VDFs are strikingly similar to those of the dark halo mass function (DMF) from N-body simulations and the stellar mass function (SMF) predicted by recent semi-analytic models of galaxy formation under the current LambdaCDM hierarchical structure formation paradigm. Interestingly, the VDF evolutions appear to be qualitatively different from ``stellar mass-downsizing'' evolutions obtained by many galaxy surveys. The coevolution of the DMF, the VDF and the SMF is investigated in quantitative detail in a following paper. We consider several possible systematic errors for the lensing analysis and find that they are not likely to alter the conclusions.(abridged)
description: MNRAS, accepted (20 pages, 12 figures), parts of section 6 of v2 moved to a following work
A study of the free-living phase of Deladenus, nematodes parasitic in woodwasps
Creators: name: Akhurst, RJ
Publisher: name: University Of Tasmania
Year: 2023

description: 1. Two populations of D. siricidicoZa and one of D. rudyi which had been maintained continuously in monoxenic culture for 1 year (D. siricidicoZa (S), D. rudyi (T)) and 6 years (D. siricidicoZa (H)) were used to study the effects of a range of environmental conditions on the egg phase of the free-living form of DeZadenus. 2. For each population the rate of egg development increased 0 0 with tempera.ture from 5 C to 25 C. 3. The abortion rate of each population was related to temperature but the nature of the relationship varied from one population to the next. In each case, abortion rate was lowest 4. There were no significant differences in the relationships of abortion rate and eclosion failure to temperature. 5. Examination of the effects of pH on the rate of egg development was inconclusive. 6. Abortion rate varied with pH from pH 2¬¨‚àë5 to pH 8‚Äö0. Different reactions were recorded for each population. Optimum pH was about pH 5¬¨‚àë5 for D. siricidicoZa (H) and D. rudyi (T), about pH 5 ‚Äö 0 for D. siricidicoZa (S). 7. \\i'i.thin each population, abortion rate and eclosion failure follm.;reC. a similar pattern of change with pH. 8. Considerable variati.on occurred between replicates in the estimation of fecundity but, on the average, D. siricidiaoZa (S) were more fecund than D. siricidico Za (H). D. rudyi (T) were more fecund when cultured on CMA rather than !t; PDA. - IV - 9. The mean volume of the eggs of D. siricidicoZa (H) was significantly greater than that of D. siricidicoZa (S) which was also significantly greater than that of D. ruayi (T). 10. The variance of egg volume of D. rudyi (T) was considerably less than that of either of the D. sirvicidicoZa populations for which the variances were not significantly different. 11. There was no correlation between the variance of the egg volume of these populations and the time interval between hatching of the first and last eggs. 12. Cross-breeding trials conducted with seven species of DeZadenus produced a wide range of results; from the parent female depositing only few eggs, all of which were abortive, to completely unimpeded production of the Fz generat:ton. 13. With only one exception, intraspecific crosses produced hybrids without reduced fecundity. 14. Interspecific crosses sometimes resulted in reduced fecundity among the parents and always among the hybrids produced. 15. The crosses, D. ruayi (UJ7) x D. rudyi (T) and D. rudyi (UJ7) J1 x D. imperiaZis !f., produced aberrant results suggesting a close relationship benveen D. rudyi and D. imperiaZis. 16. Differences between D. siricidicoZa (H) and the other two populations indicated that considerable changes can result from continuous cultures of the type used for DeZadenus. 17. Differences between D. sirim:dicoZa (S) and D. siricidicoZa (H) inr:lic12te that the cultures of these populations should be regarded as differen': strains.
Charge transport in graphene with resonant scatterers
Creators: name: Titov, M.
name: Ostrovsky, P. M.
name: Gornyi, I. V.
name: Schuessler, A.
name: Mirlin, A. D.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The full counting statistics for the charge transport through an undoped graphene sheet in the presence of strong potential impurities is studied. Treating the scattering off the impurity in the s-wave approximation, we calculate the impurity correction to the cumulant generating function. This correction is universal provided the impurity strength is tuned to a resonant value. In particular, the conductance of the sample acquires a correction of 16e^2/(pi^2 h) per resonant impurity.
description: 11 pages, 6 figures; published version, appendix with technical details added
How to Engineer Organic Solvent Resistant Enzymes: Insights from Combined Molecular Dynamics and Directed Evolution Study
Creators: name: Cui, Haiyang
name: Stadtmüller, Tom H.J.
name: Jiang, Qianjia
name: Jaeger, Karl-Erich
name: Schwaneberg, Ulrich
name: Davari, Mehdi D.
Publisher: name: Weinheim : Wiley-VCH
Year: 2020
Subjects: subject: Bacillus subtilis Lipase A
subject: biocatalysis
subject: directed evolution
subject: molecular dynamics simulation
subject: organic solvent
subject: 540

description: Expanding synthetic capabilities to routinely employ enzymes in organic solvents (OSs) is a dream for protein engineers and synthetic chemists. Despite significant advances in the field of protein engineering, general and transferable design principles to improve the OS resistance of enzymes are poorly understood. Herein, we report a combined computational and directed evolution study of Bacillus subtlis lipase A (BSLA) in three OSs (i. e., 1,4-dioxane, dimethyl sulfoxide, 2,2,2-trifluoroethanol) to devise a rational strategy to guide engineering OS resistant enzymes. Molecular dynamics simulations showed that OSs reduce BSLA activity and resistance in OSs by (i) stripping off essential water molecules from the BLSA surface mainly through H-bonds binding; and (ii) penetrating the substrate binding cleft leading to inhibition and conformational change. Interestingly, integration of computational results with “BSLA-SSM” variant library (3439 variants; all natural diversity with amino acid exchange) revealed two complementary rational design strategies: (i) surface charge engineering, and (ii) substrate binding cleft engineering. These strategies are most likely applicable to stabilize other lipases and enzymes and assist experimentalists to design organic solvent resistant enzymes with reduced time and screening effort in lab experiments. © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA
The environment of the Permian Glacial sedimentation of Tasmania: with particular reference to the base of the Permian
Creators: name: Ahmad, N
Publisher: name: University Of Tasmania
Year: 2023

description: In Tasmania during the Lower Permian Epoch glaciers not only reached sea level but in places extended on the sea as shelf ice. Where-ever glaciers rested on tbe land tillites were deposited but under the shelf ice deposits of various types were laid down. During this time icebergs were quite common and large iceborne erraticd were deposited side by side witb marine fossils. Conditions both on land and sea were very similar to those that exiat today in the Antarctic region. Tba glaciers flowed in part from a land mass lying west of the present west coast of Tasmania, which lay within 40¬¨‚àû of the South Pole. Waxing and waning of the glaciers is indicated by differences in the sediments, and by increase and decrease in tbe number and size of the erratica. The gradual retreat of the ice sheet was followed by warm water sediments in the Trissic Period.
Electronic materials with a wide band gap: Recent developments
Creators: name: Klimm, D.
Publisher: name: Chester : International Union of Crystallography
Year: 2014
Subjects: subject: electronic materials
subject: germanium
subject: semiconductors
subject: silicon
subject: wide band gap materials
subject: 540

description: The development of semiconductor electronics is reviewed briefly, beginning with the development of germanium devices (band gap E g = 0.66 eV) after World War II. A tendency towards alternative materials with wider band gaps quickly became apparent, starting with silicon (E g = 1.12 eV). This improved the signal-to-noise ratio for classical electronic applications. Both semiconductors have a tetrahedral coordination, and by isoelectronic alternative replacement of Ge or Si with carbon or various anions and cations, other semiconductors with wider E g were obtained. These are transparent to visible light and belong to the group of wide band gap semiconductors. Nowadays, some nitrides, especially GaN and AlN, are the most important materials for optical emission in the ultraviolet and blue regions. Oxide crystals, such as ZnO and β-Ga2O3, offer similarly good electronic properties but still suffer from significant difficulties in obtaining stable and technologically adequate p-type conductivity.