cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus
Creators: name: Bertrams, Wilhelm
name: Hönzke, Katja
name: Obermayer, Benedikt
name: Tönnies, Mario
name: Bauer, Torsten T.
name: Schneider, Paul
name: Neudecker, Jens
name: Rückert, Jens C.
name: Stiewe, Thorsten
name: Nist, Andrea
name: Eggeling, Stephan
name: Suttorp, Norbert
name: Wolff, Thorsten
name: Hippenstiel, Stefan
name: Schmeck, Bernd
name: Hocke, Andreas C.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: A549 Cells
subject: Alveolar Epithelial Cells
subject: Influenza A virus
subject: Transcriptome
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Influenza A virus (IAV) causes pandemics and annual epidemics of severe respiratory infections. A better understanding of the molecular regulation in tissue and cells upon IAV infection is needed to thoroughly understand pathogenesis. We analyzed IAV replication and gene expression induced by IAV strain H3N2 Panama in isolated primary human alveolar epithelial type II cells (AECIIs), the permanent A549 adenocarcinoma cell line, alveolar macrophages (AMs) and explanted human lung tissue by bulk RNA sequencing. Primary AECII exhibit in comparison to AM a broad set of strongly induced genes related to RIG-I and interferon (IFN) signaling. The response of AECII was partly mirrored in A549 cells. In human lung tissue, we observed induction of genes unlike in isolated cells. Viral RNA was used to correlate host cell gene expression changes with viral burden. While relative induction of key genes was similar, gene abundance was highest in AECII cells and AM, while weaker in the human lung (due to less IAV replication) and A549 cells (pointing to their limited suitability as a model). Correlation of host gene induction with viral burden allows a better understanding of the cell-type specific induction of pathways and a possible role of cellular crosstalk requiring intact tissue.
D5.5: Policy brief: strengthening open responsible research and innovation
Creators: name: Griessler, Erich
name: Berghäuser, Hendrik
name: Hüttel, Emil Bories
name: Brasil, André
name: Bührer, Susanne
name: Carlsen, Signe
name: Ballo, Ingrid Foss
name: Ryan, Thomas Kjeldager
name: van der Klippe, Wouter
name: Lindner, Ralf
name: Meijer, Ingeborg
name: Mejlgaard, Niels
name: Otero-Hermida, Paula
name: Perruchas, François
name: Rommetveit, Kjetil
name: Stack, Shauna
name: Strand, Roger
name: Wicher, Magdalena
name: Wienand, Carolina
name: Wooley, Richard
name: Yorulmaz, Merve
Publisher: name: Zenodo
Year: 2023

description: In this policy brief, SUPER MoRRI results and insights are presented in a concise form, drawing from various studies conducted in the project.
Sammelband: Historia trium regum; Gesta Romanorum; Johannes Gerson
Creators: name: Johannes
name: Gerson, Jean
Publisher: name: [s.n.]
Year: 1444

description: Öffentliche Bibliothek der Universität Basel
description: Lateinisch
description: Die Hs. hat drei Teile, die alle im Predigerkloster oder jedenfalls in Basel während des Konzils entstanden sein dürften, schon früh zusammengebunden wurden, aber auch unabhängig von einander bestehen könnten. Hände und Buchschmuck sind verschieden; das Vorsatzblatt war ein erster Entwurf für Teil 2. Die Historia trium regum ist am Ende (40ra) auf den 22. Januar 1444 datiert und explizit in Basel geschrieben; Conradus Hebenhamer, der überlieferte Schreiber dieses Teils, ist wohl kaum der in Salzburg, Bern und Landshut (vgl. CMD-CH 2, Textband S. 255) nachgewiesene, 1513 gestorbene Träger dieses Namens aus Nürnberg (vgl. Die illuminierten Handschriften und Inkunabeln in Österreich ausserhalb der Österreichischen Nationalbilbiothek, Bd. 6/1, S. 260 zu Linz, Oberösterreichische Landesbibliothek, Ink 349), wie der Zusatz "senior" auch andeutet. Auch der letzte der Tractate von Jean Gerson in Teil 3 ist auf das gleiche Jahr datiert, als Schreiber nennt sich Oswald Memminger, Teilnehmer am Basler Konzil (210v); am Ende des letzten Texts (215v) steht allerdings die Jahreszahl 1441. 1v "Iste liber est fratrum ordinis predicatorum domus Basiliensis". Im vorderen Spiegel ganz oben, 16. Jh.: "Est Academiae Basiliensis". 1r, 2r und 215v Bibliotheksstempel (oval, 2 x 3 cm): "Bibl. publ. Basileensis", um 1800, vgl. Agnes Wegmann, Schweizer Exlibris bis zum Jahre 1900, Bd. 1, Zürich 1933, Nr. 368/369.
description: Verzeichnung=Description=Inventaire Jan. 2010 und Sept. 2012 Minimalaufnahme nach: NN, unpublizierte Beschreibung
description: Verzeichnung=Description=Inventaire Aug. 2024 Normalaufnahme nach Autopsie Mangold
description: Digitalisierung=Digitization=Numérisation Aug. 2024 TIFF
description: Erschliessungsniveau Normalniveau
1918/9 : Ausleih-Journal
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1918

description: Öffentliche Bibliothek der Universität Basel
description: Deutsch
description: Verzeichnung=Description=Inventaire Februar 2024 HAN-Katalogisierungsregeln Minimalaufnahme nach Autopsie
description: Digitalisierung=Digitization=Numérisation Februar 2024 TIFF
description: Erschliessungsniveau Minimalniveau
description: Beil. 1: 1 Zettel mit Rückgaben bis 29. Okt. 1920
Peripheral skin cooling during hyper-gravity: hemodynamic reactions
Creators: name: Kagelmann, Niklas
name: Janke, David
name: Maggioni, Martina Anna
name: Gunga, Hanns-Christian
name: Riveros Rivera, Alain
name: Genov, Magdalena
name: Noppe, Alexandra
name: Habazettl, Helmut
name: Bothe, Tomas Lucca
name: Nordine, Michael
name: Castiglioni, Paolo
name: Opatz, Oliver
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: hyper-gravity
subject: hyper-gravity centrifuge model tests
subject: spaceflight countermeasures
subject: G-induced loss of consciousness
subject: short-arm human centrifuge
subject: orthostatic instability
subject: cardiovascular stability
subject: peripheral external cooling
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Orthostatic dysregulation occurs during exposure to an increased gravitational vector and is especially common upon re-entering standard Earth gravity (1 g) after an extended period in microgravity (0 g). External peripheral skin cooling (PSC) has recently been described as a potent countermeasure against orthostatic dysregulation during heat stress and in lower body negative pressure (LBNP) studies. We therefore hypothesized that PSC may also be an effective countermeasure during hyper-gravity exposure (+Gz). Methods: To investigate this, we designed a randomized short-arm human centrifuge (SAHC) experiment ("Coolspin") to investigate whether PSC could act as a stabilizing factor in cardiovascular function during+Gz. Artificial gravity between +1 g and+4 gwas generated by a SAHC. 18 healthy male volunteers completed two runs in the SAHC. PSC was applied during one of the two runs and the other run was conducted without cooling. Each run consisted of a 10-min baseline trial followed by a +Gz step protocol marked by increasing g-forces, with each step being 3min long. The following parameters were measured: blood pressure (BP), heart rate (HR), stroke volume (SV), total peripheral resistance (TPR), cardiac output (CO). Furthermore, a cumulative stress index for each subject was calculated. Results: +Gz led to significant changes in primary as well as in secondary outcome parameters such as HR, SV, TPR, CO, and BP. However, none of the primary outcome parameters (HR, cumulative stress-index, BP) nor secondary outcome parameters (SV, TPR, CO) showed any significant differences-whether the subject was cooled or not cooled. Systolic BP did, however, tend to be higher amongst the PSC group. Conclusion: In conclusion, PSC during +Gz did not confer any significant impact on hemodynamic activity or orthostatic stability during +Gz. This may be due to lower PSC responsiveness of the test subjects, or an insufficient level of body surface area used for cooling. Further investigations are warranted in order to comprehensively pinpoint the exact degree of PSC needed to serve as a useful countermeasure system during +Gz.
Additional file 6: of Improving performance of the Tariff Method for assigning causes of death to verbal autopsies
Creators: name: Serina, Peter
name: Riley, Ian
name: Stewart, Andrea
name: James, Spencer
name: Flaxman, Abraham
name: Lozano, Rafael
name: Hernandez, Bernardo
name: Mooney, Meghan
name: Luning, Richard
name: Black, Robert
name: Ahuja, Ramesh
name: Alam, Nurul
name: Alam, Sayed
name: Ali, Said
name: Atkinson, Charles
name: Baqui, Abdulla
name: Hafizur Chowdhury
name: Dandona, Lalit
name: Dandona, Rakhi
name: Dantzer, Emily
name: Darmstadt, Gary
name: Das, Vinita
name: Dhingra, Usha
name: Dutta, Arup
name: Wafaie Fawzi
name: Freeman, Michael
name: Gomez, Sara
name: Hebe Gouda
name: Rohina Joshi
name: Kalter, Henry
name: Kumar, Aarti
name: Vishwajeet Kumar
name: Marilla Lucero
name: Seri Maraga
name: Saurabh Mehta
name: Neal, Bruce
name: Ohno, Summer
name: Phillips, David
name: Pierce, Kelsey
name: Prasad, Rajendra
name: Devarsatee Praveen
name: Zul Premji
name: Ramirez-Villalobos, Dolores
name: Rarau, Patricia
name: Remolador, Hazel
name: Romero, Minerva
name: Mwanaidi Said
name: Diozele Sanvictores
name: Sazawal, Sunil
name: Streatfield, Peter
name: Tallo, Veronica
name: Alireza Vadhatpour
name: Vano, Miriam
name: Murray, Christopher
name: Lopez, Alan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Chance-corrected concordance for 11 neonate causes. (DOCX 16 kb)
Lohmannia pseudoturcmenica Ermilov 2017
Creators: name: Norton, Roy A.
name: Ermilov, Sergey G.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Lohmanniidae
Lohmannia
Lohmannia pseudoturcmenica

description: Lohmannia pseudoturcmenica Ermilov, 2017
Tritonymph: Ermilov 2017 (Ds, FB, FGn, LSA)
description: Published as part of Norton, Roy A. & Ermilov, Sergey G., 2024, Catalogue of juvenile instars of oribatid mites (Acari: Oribatida) - the next decade (2014 - 2023), pp. 451-494 in Zootaxa 5419 (4) on page 454, DOI: 10.11646/zootaxa.5419.4.1, http://zenodo.org/record/10798799
title: PlanRomePlaque01 26
Creators: name: Galinand, Cyrille
name: Orient & Méditerranée UMR8167
Publisher: name: Archeovision
Year: 2024
Subjects: subject: Rome antique
subject: plan relief
subject: Paul Bigot

description: Plan de la Rome antique
description: 1 fichier 3D (ply), 184 fichiers image (jpg)
Primary radiation damage in bone evolves via collagen destruction by photoelectrons and secondary emission self-absorption
Creators: name: Sauer, Katrein
name: Zizak, Ivo
name: Forien, Jean-Baptiste
name: Rack, Alexander
name: Scoppola, Ernesto
name: Zaslansky, Paul
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Bone and Bones
subject: Electrons
subject: X-Ray Diffraction
subject: X-Rays
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: X-rays are invaluable for imaging and sterilization of bones, yet the resulting ionization and primary radiation damage mechanisms are poorly understood. Here we monitor in-situ collagen backbone degradation in dry bones using second-harmonic-generation and X-ray diffraction. Collagen breaks down by cascades of photon-electron excitations, enhanced by the presence of mineral nanoparticles. We observe protein disintegration with increasing exposure, detected as residual strain relaxation in pre-stressed apatite nanocrystals. Damage rapidly grows from the onset of irradiation, suggesting that there is no minimal ‘safe’ dose that bone collagen can sustain. Ionization of calcium and phosphorous in the nanocrystals yields fluorescence and high energy electrons giving rise to structural damage that spreads beyond regions directly illuminated by the incident radiation. Our findings highlight photoelectrons as major agents of damage to bone collagen with implications to all situations where bones are irradiated by hard X-rays and in particular for small-beam mineralized collagen fiber investigations.
MOESM1 of Synovial fluid proteome in rheumatoid arthritis
Creators: name: Mitali Bhattacharjee
name: Lavanya Balakrishnan
name: Renuse, Santosh
name: Advani, Jayshree
name: Goel, Renu
name: Gajanan Sathe
name: T. Keshava Prasad
name: Bipin Nair
name: Jois, Ramesh
name: Shankar, Subramanian
name: Akhilesh Pandey
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Computational Biology

description: Additional file 1: Table S1. Clinical details of patients used in the study.
Mentalizing in the context of Mentzos’ dilemma–on the use of implicit work in the treatment of non-affective psychosis
Creators: name: Bröcker, Anna-Lena
name: Haebler, Dorothea Von
name: Lempa, Günter
name: Montag, Christiane
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: mentalizing
subject: metacognition
subject: psychosis
subject: schizophrenia
subject: dilemma
subject: implicit
subject: explicit
subject: psychotherapy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Current approaches to the treatment of non-affective psychosis include elements of mentalization-based treatment and the potential in enhancing mentalizing capacity in this patient group has been widely emphasized. This article presents the "psychotic identity dilemma", a concept by Stavros Mentzos, and a therapeutic approach considering this concept as a valuable complementary addition to these treatments. The idea of a dilemma between closeness and distance, which in itself cannot be represented mentally at first, helps to respond to specific needs of patients with psychotic disorders by placing the treatment focus on fundamental interpersonal processes. Following this train of thought, this article attempts to shed light on the importance of the "real relationship" between therapist and patient as well as the exploration of the "here and now", especially at the beginning of psychotherapeutic treatment. Two treatment modes are suggested, one characterized by the experience of interpersonality within the therapeutic relationship and a second one characterized by the reflection of interpersonal phenomena. These modes are framed by Stavros Mentzos' concept of an identity dilemma. We describe how mentalizing first needs to be addressed implicitly in a tolerable, exemplary relationship in which closeness and distance are regulated based on the therapist's countertransference, then explicitly. A series of interventions are described, which allow for moments of shared attention, promote intentionality and contingency and, later in the course of therapy, help to integrate experiences into narratives.
Additional file 2: of Improving performance of the Tariff Method for assigning causes of death to verbal autopsies
Creators: name: Serina, Peter
name: Riley, Ian
name: Stewart, Andrea
name: James, Spencer
name: Flaxman, Abraham
name: Lozano, Rafael
name: Hernandez, Bernardo
name: Mooney, Meghan
name: Luning, Richard
name: Black, Robert
name: Ahuja, Ramesh
name: Alam, Nurul
name: Alam, Sayed
name: Ali, Said
name: Atkinson, Charles
name: Baqui, Abdulla
name: Hafizur Chowdhury
name: Dandona, Lalit
name: Dandona, Rakhi
name: Dantzer, Emily
name: Darmstadt, Gary
name: Das, Vinita
name: Dhingra, Usha
name: Dutta, Arup
name: Wafaie Fawzi
name: Freeman, Michael
name: Gomez, Sara
name: Hebe Gouda
name: Rohina Joshi
name: Kalter, Henry
name: Kumar, Aarti
name: Vishwajeet Kumar
name: Marilla Lucero
name: Seri Maraga
name: Saurabh Mehta
name: Neal, Bruce
name: Ohno, Summer
name: Phillips, David
name: Pierce, Kelsey
name: Prasad, Rajendra
name: Devarsatee Praveen
name: Zul Premji
name: Ramirez-Villalobos, Dolores
name: Rarau, Patricia
name: Remolador, Hazel
name: Romero, Minerva
name: Mwanaidi Said
name: Diozele Sanvictores
name: Sazawal, Sunil
name: Streatfield, Peter
name: Tallo, Veronica
name: Alireza Vadhatpour
name: Vano, Miriam
name: Murray, Christopher
name: Lopez, Alan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Cause of death exclusion criteria for Tariff 2.0. (DOCX 13 kb)
Additional file 5: of Improving performance of the Tariff Method for assigning causes of death to verbal autopsies
Creators: name: Serina, Peter
name: Riley, Ian
name: Stewart, Andrea
name: James, Spencer
name: Flaxman, Abraham
name: Lozano, Rafael
name: Hernandez, Bernardo
name: Mooney, Meghan
name: Luning, Richard
name: Black, Robert
name: Ahuja, Ramesh
name: Alam, Nurul
name: Alam, Sayed
name: Ali, Said
name: Atkinson, Charles
name: Baqui, Abdulla
name: Hafizur Chowdhury
name: Dandona, Lalit
name: Dandona, Rakhi
name: Dantzer, Emily
name: Darmstadt, Gary
name: Das, Vinita
name: Dhingra, Usha
name: Dutta, Arup
name: Wafaie Fawzi
name: Freeman, Michael
name: Gomez, Sara
name: Hebe Gouda
name: Rohina Joshi
name: Kalter, Henry
name: Kumar, Aarti
name: Vishwajeet Kumar
name: Marilla Lucero
name: Seri Maraga
name: Saurabh Mehta
name: Neal, Bruce
name: Ohno, Summer
name: Phillips, David
name: Pierce, Kelsey
name: Prasad, Rajendra
name: Devarsatee Praveen
name: Zul Premji
name: Ramirez-Villalobos, Dolores
name: Rarau, Patricia
name: Remolador, Hazel
name: Romero, Minerva
name: Mwanaidi Said
name: Diozele Sanvictores
name: Sazawal, Sunil
name: Streatfield, Peter
name: Tallo, Veronica
name: Alireza Vadhatpour
name: Vano, Miriam
name: Murray, Christopher
name: Lopez, Alan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Chance-corrected concordance for 21 child causes. (DOCX 19 kb)
Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Creators: name: Petter, Elisabeth
name: Scheibenbogen, Carmen
name: Linz, Peter
name: Stehning, Christian
name: Wirth, Klaus
name: Kuehne, Titus
name: Kelm, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2022
Subjects: subject: Chronic Fatigue Syndrome
subject: Sodium
subject: Magnetic Resonance Imaging
subject: Muscle
subject: Skeletal
subject: Myalgia
subject: Exercise
subject: Sodium-potassium-exchanging ATPase
subject: Sodium-hydrogen exchangers
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Muscle fatigue and pain are key symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Although the pathophysiology is not yet fully understood, there is ample evidence for hypoperfusion which may result in electrolyte imbalance and sodium overload in muscles. Therefore, the aim of this study was to assess levels of sodium content in muscles of patients with ME/CFS and to compare these to healthy controls. Methods: Six female patients with ME/CFS and six age, BMI and sex matched controls underwent Na-23-MRI of the left lower leg using a clinical 3T MR scanner before and after 3 min of plantar flexion exercise. Sodium reference phantoms with solutions of 10, 20, 30 and 40 mmol/L NaCl were used for quantification. Muscle sodium content over 40 min was measured using a dedicated plugin in the open-source DICOM viewer Horos. Handgrip strength was measured and correlated with sodium content. Results: Baseline tissue sodium content was higher in all 5 lower leg muscle compartments in ME/CFS compared to controls. Within the anterior extensor muscle compartment, the highest difference in baseline muscle sodium content between ME/CFS and controls was found (mean ± SD; 12.20 ± 1.66 mM in ME/CFS versus 9.38 ± 0.71 mM in controls, p = 0.0034). Directly after exercise, tissue sodium content increased in gastrocnemius and triceps surae muscles with + 30% in ME/CFS (p = 0.0005) and + 24% in controls (p = 0.0007) in the medial gastrocnemius muscle but not in the extensor muscles which were not exercised. Compared to baseline, the increase of sodium content in medial gastrocnemius muscle was stronger in ME/CFS than in controls with + 30% versus + 17% to baseline at 12 min (p = 0.0326) and + 29% versus + 16% to baseline at 15 min (p = 0.0265). Patients had reduced average handgrip strength which was associated with increased average muscle tissue sodium content (p = 0.0319, R-2 = 0.3832). Conclusion: Muscle sodium content before and after exercise was higher in ME/CFS than in healthy controls. Furthermore, our findings indicate an inverse correlation between muscle sodium content and handgrip strength. These findings provide evidence that sodium overload may play a role in the pathophysiology of ME/CFS and may allow for potential therapeutic targeting.
Additional file 3: of Improving performance of the Tariff Method for assigning causes of death to verbal autopsies
Creators: name: Serina, Peter
name: Riley, Ian
name: Stewart, Andrea
name: James, Spencer
name: Flaxman, Abraham
name: Lozano, Rafael
name: Hernandez, Bernardo
name: Mooney, Meghan
name: Luning, Richard
name: Black, Robert
name: Ahuja, Ramesh
name: Alam, Nurul
name: Alam, Sayed
name: Ali, Said
name: Atkinson, Charles
name: Baqui, Abdulla
name: Hafizur Chowdhury
name: Dandona, Lalit
name: Dandona, Rakhi
name: Dantzer, Emily
name: Darmstadt, Gary
name: Das, Vinita
name: Dhingra, Usha
name: Dutta, Arup
name: Wafaie Fawzi
name: Freeman, Michael
name: Gomez, Sara
name: Hebe Gouda
name: Rohina Joshi
name: Kalter, Henry
name: Kumar, Aarti
name: Vishwajeet Kumar
name: Marilla Lucero
name: Seri Maraga
name: Saurabh Mehta
name: Neal, Bruce
name: Ohno, Summer
name: Phillips, David
name: Pierce, Kelsey
name: Prasad, Rajendra
name: Devarsatee Praveen
name: Zul Premji
name: Ramirez-Villalobos, Dolores
name: Rarau, Patricia
name: Remolador, Hazel
name: Romero, Minerva
name: Mwanaidi Said
name: Diozele Sanvictores
name: Sazawal, Sunil
name: Streatfield, Peter
name: Tallo, Veronica
name: Alireza Vadhatpour
name: Vano, Miriam
name: Murray, Christopher
name: Lopez, Alan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Tariff and GBD weights for a 45-year-old male in the Philippines. (DOCX 15 kb)
In vitro induction of Entamoeba gingivalis cyst-like structures from trophozoites in response to antibiotic treatment
Creators: name: Becker, Christin
name: Adam, Aysegül
name: Dommisch, Henrik
name: Stach, Thomas
name: Schaefer, Arne S.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: Entamoeba gingivalis
subject: cysts
subject: encystation
subject: periodontitis
subject: periimplantitis
subject: antibiotics
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Entamoeba gingivalis (E. gingivalis) is an anaerobic protozoan that is strongly associated with inflamed periodontal pockets. It is able to invade the mucosal epithelium of the human host, where it can feed on epithelial cells and elicit a severe innate immune response. Unlike other Entamoeba species, it is considered that E. gingivalis cannot form cysts, because it is a non-infectious protozoan. The lack of encystation capability would make it susceptible to periodontal treatment. However, it is not clear how the human host becomes infected with E. gingivalis trophozoites. We investigated the ability of E. gingivalis to encapsulate in response to an unfavorable environment in vitro. Methods: Different strains of E. gingivalis, isolated from inflamed periodontal pocket samples, were cultured for 8 days in the presence or absence of the antimicrobials amoxycillin and metronidazole. To reveal cyst formation, we investigated the morphology and ultrastructure of the amoeba by light, fluorescence, transmission and scanning electron microscopy. We also used the fluorescent dye calcofluor white M2R to demonstrate chitin present in the cyst wall. Results: We observed exocysts and an intra-cystic space separating the encapsulated trophozoite from the environment. Remarkably, cysts showed a smooth surface, polygonal edges and smaller size compared to free-living trophozoites. In addition, encapsulated trophozoites that detached from the cyst wall had a dense cytoplasma without phagocytic vesicles. The cyst walls consisted of chitin as in other Entamoba species. The encapsulated trophozoids were mononuclear after antibioticinduced encapsulation. Discussion: We conclude that E. gingivalis cyst formation has significant implications for dissemination and infection and may explain why established treatment approaches often fail to halt periodontal tissue destruction during periodontitis and peri-implantitis.
title: Réduire l’impact climatique de notre alimentation: ce que des collectivités territoriales françaises et allemandes peuvent nous apprendre
Creators: name: Ratzmann, Nora
name: Faltermeier, Kathrin
name: Plessing, Julia
Publisher: name: Research Institute For Sustainability – Helmholtz Centre Potsdam
publisherIdentifier: https://ror.org/01vvnmw35
publisherIdentifierScheme: ROR
Year: 2024

description: L’alimentation est à la fois un levier central pour engager la transition socio-écologique et un theme quotidien tangible pour chaque citoyen.ne. En Allemagne comme en France, quelques collectivités territoriales engagent des mesures innovantes pour promouvoir une alimentation locale et durable. Le Forum pour l’avenir franco-allemand s’est penché sur les expériences de certaines de ces collectivités et a facilité le dialogue entre elles durant plusieurs mois afin de comprendre quelles politiques nationales peuvent soutenir de telles initiatives locales. En associant des expert.e.s issus de la sphère scientifique, de l’administration et de la société civile, il a recommandé de « Donner la priorité au développement de systèmes alimentaires locaux et durables » avec cinq propositions d’action concrètes aux gouvernements français et allemand. Cette étude présente les initiatives françaises et allemandes ayant nourri les propositions d’action du Forum pour l’avenir.
description: Food and food policy is central to social-ecological transformation. It is also an everyday issue that is easy to communicate to citizens. Municipalities in Germany and France have recognized the potential of innovative local food policies and have developed and tested innovative approaches to transforming local food systems. However, they are encountering structural barriers that cannot be overcome at the municipal level. The Franco-German Forum for the Future has researched the opportunities and obstacles of local nutritional change and brought engaged municipalities from both countries into exchange with each other. Together with experts from academia, public administrations and civil society, it has developed the seven recommendations for the national governments, one of which concerns "Prioritizing the development of local and sustainable food systems" with five proposals for action. This study is intended as a background paper to the Recommendation. With recourse to the concrete example of Mouans-Sartoux and other municipalities in France and Germany, it describes the potentials of a sustainable municipal food policy and provides – from concrete local practice – the background knowledge for each of the five proposals for action.
Mesoplophora quasigaveae Niedbala 2016
Creators: name: Norton, Roy A.
name: Ermilov, Sergey G.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Mesoplophoridae
Mesoplophora
Mesoplophora quasigaveae

description: Mesoplophora quasigaveae Niedbała, 2016
Deutonymph: Ermilov, Niedbała & Friedrich 2016 (Ds, FB, LSF)
Tritonymph: Ermilov, Niedbała & Friedrich 2016 (Ds, FB, LSF)
description: Published as part of Norton, Roy A. & Ermilov, Sergey G., 2024, Catalogue of juvenile instars of oribatid mites (Acari: Oribatida) - the next decade (2014 - 2023), pp. 451-494 in Zootaxa 5419 (4) on page 454, DOI: 10.11646/zootaxa.5419.4.1, http://zenodo.org/record/10798799
Additional file 7: of Improving performance of the Tariff Method for assigning causes of death to verbal autopsies
Creators: name: Serina, Peter
name: Riley, Ian
name: Stewart, Andrea
name: James, Spencer
name: Flaxman, Abraham
name: Lozano, Rafael
name: Hernandez, Bernardo
name: Mooney, Meghan
name: Luning, Richard
name: Black, Robert
name: Ahuja, Ramesh
name: Alam, Nurul
name: Alam, Sayed
name: Ali, Said
name: Atkinson, Charles
name: Baqui, Abdulla
name: Hafizur Chowdhury
name: Dandona, Lalit
name: Dandona, Rakhi
name: Dantzer, Emily
name: Darmstadt, Gary
name: Das, Vinita
name: Dhingra, Usha
name: Dutta, Arup
name: Wafaie Fawzi
name: Freeman, Michael
name: Gomez, Sara
name: Hebe Gouda
name: Rohina Joshi
name: Kalter, Henry
name: Kumar, Aarti
name: Vishwajeet Kumar
name: Marilla Lucero
name: Seri Maraga
name: Saurabh Mehta
name: Neal, Bruce
name: Ohno, Summer
name: Phillips, David
name: Pierce, Kelsey
name: Prasad, Rajendra
name: Devarsatee Praveen
name: Zul Premji
name: Ramirez-Villalobos, Dolores
name: Rarau, Patricia
name: Remolador, Hazel
name: Romero, Minerva
name: Mwanaidi Said
name: Diozele Sanvictores
name: Sazawal, Sunil
name: Streatfield, Peter
name: Tallo, Veronica
name: Alireza Vadhatpour
name: Vano, Miriam
name: Murray, Christopher
name: Lopez, Alan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Marine Biology
subject: Science Policy

description: Descriptive information comparing community VAs to gold standard validation data. (DOCX 17 kb)
The relevance of body composition assessment for the rating of perceived exertion in trained and untrained women and men
Creators: name: Lichti, Julia
name: Maggioni, Martina Anna
name: Balcerek, Björn
name: Becker, Philipp Nils
name: Labes, Robert
name: Gunga, Hanns-Christian
name: Fähling, Michael
name: Steinach, Mathias
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: body composition
subject: Borg scale
subject: Bruce protocol
subject: endurance
subject: exercise test
subject: exertion
subject: training status
subject: sex
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Introduction: Mechanic power output (MPO) and oxygen consumption (VO2) reflect endurance capacity and are often stated relative to body mass (BM) but less often per skeletal muscle mass (SMM). Rating of perceived exertion (RPE) has previously shown conflicting results between sexes at submaximal intensities. Individual body composition, however, largely differs due to sex and training status. It was the aim of this study to evaluate RPE of untrained and trained individuals of both sexes considering body composition and to estimate whether RPE could be improved as a tool to determine endurance capacity. Methods: The study included 34 untrained adults (age 26.18 ± 6.34 years, 18 women) and 29 endurance trained (age 27.86 ± 5.19, 14 women) who were measured for body composition (InBody 770, InBody Europe B.V., Germany) and tested on a treadmill (Pulsar, H/P/Cosmos, Germany) for aerobic capacity (Metalyzer 3B, Cortex Biophysik GmbH, Germany) in an all-out exercise test applying the Bruce-protocol. VO2, MPO, heart rate (HR), and RPE were obtained at each exercise stage. VO2 and MPO were calculated per BM and SMM. RPE values were correlated with absolute VO2 and MPO, as well as relative to BM, and SMM. HR values and the parameters’ standardized values served for comparison to standard procedures. Results: VO2 and MPO were higher in men compared to women and in trained compared to untrained participants. No differences between groups and sexes exist when VO2 and MPO were calculated per BM. When calculated per SMM, VO2 and MPO indicate opposite results already at low intensity stages of exercise test. RPE values had highest correlation with MPO per SMM (R2 = 0.8345) compared to absolute MPO (R2 = 0.7609), or MPO per BM (R2 = 0.8176). Agreement between RPE and MPO per SMM was greater than between RPE and HR (p = 0.008). Conclusion: Although RPE represents a subjective value at first glance, it was shown that RPE constitutes a valuable tool to estimate endurance capacity, which can be further enhanced if individual body composition is considered. Furthermore, MPO and VO2 should be considered relative to SMM. These findings might help to avoid over-exertion, especially among untrained people, by adjusting the training intensity for each subject according to the individual strain evaluated in an exercise test based on individual body composition.
Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation
Creators: name: Barbieri, Fabian
name: Mattig, Isabel
name: Beyhoff, Niklas
name: Thevathasan, Tharusan
name: Romero Dorta, Elena
name: Skurk, Carsten
name: Stangl, Karl
name: Landmesser, Ulf
name: Kasner, Mario
name: Dreger, Henryk
name: Reinthaler, Markus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: atrial functional tricuspid regurgitation
subject: ventricular functional tricuspid regurgitation
subject: transcatheter annuloplasty
subject: Cardioband®
subject: interventional echocardiography
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Transcatheter annuloplasty is meant to target annular dilatation and is therefore mainly applied in functional tricuspid regurgitation (TR). Due to recent recognition of varying disease pathophysiology and differentiation of ventricular and atrial functional TR (VFTR and AFTR), comparative data regarding procedural success for both disease entities are required. Methods: In this consecutively enrolled observational cohort study, 65 patients undergoing transcatheter annuloplasty with a Cardioband® device were divided into VFTR (n = 35, 53.8%) and AFTR (n = 30, 46.2%). Procedural success was assessed by comparing changes in annulus dilatation, vena contracta (VC) width, effective regurgitation orifice area (EROA), as well as reduction in TR severity. Results: Overall, improvement of TR by at least two grades was achieved in 59 patients (90.8%), and improvement of TR by at least three grades was realised in 32 patients (49.2%). Residual TR of ≤2 was observed in 52 patients (80.0%). No significant differences in annulus diameter reduction [VFTR: 11 mm (9–13) vs. AFTR: 12 mm (9–16), p = 0.210], VC reduction [12 mm (8–14) vs. 12 mm (7–14), p = 0.868], and EROA reduction [0.62 cm2 (0.45–1.10) vs. 0.54 cm2 (0.40–0.70), p = 0.204] were reported. Improvement by at least two grades [27 (90.0%) vs. 32 (91.4%), p = 1.0] and three grades [14 (46.7%) vs. 18 (51.4%), p = 0.805] was similar in VFTR and AFTR, respectively. No significant difference in the accomplishment of TR grade of ≤2 [21 (70.0%) vs. 31 (88.6%), p = 0.118] was noted. Conclusion: According to our results from a real-world scenario, transcatheter annuloplasty with the Cardioband® device may be applied in both VFTR and AFTR with evidence of significant procedural TR reduction.
Cosmochthonius oralensis S. Seniczak, A. Seniczak, Kaczmarek, Marquardt & Jangazieva 2020
Creators: name: Norton, Roy A.
name: Ermilov, Sergey G.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Cosmochthoniidae
Cosmochthonius
Cosmochthonius oralensis

description: Cosmochthonius oralensis S. Seniczak, A. Seniczak, Kaczmarek, Marquardt & Jangazieva, 2020
Larva: S. Seniczak, A. Seniczak, Kaczmarek, Marquardt & Jangazieva 2020 (Ds, FB, FLg, LSA)
Protonymph: S. Seniczak, A. Seniczak, Kaczmarek, Marquardt & Jangazieva 2020 (Ds, FB, LSA)
Deutonymph: S. Seniczak, A. Seniczak, Kaczmarek, Marquardt & Jangazieva 2020 (Ds, FB, LSA)
Tritonymph: S. Seniczak, A. Seniczak, Kaczmarek, Marquardt & Jangazieva 2020 (Ds, FB, FLg, LSA)
description: Published as part of Norton, Roy A. & Ermilov, Sergey G., 2024, Catalogue of juvenile instars of oribatid mites (Acari: Oribatida) - the next decade (2014 - 2023), pp. 451-494 in Zootaxa 5419 (4) on page 454, DOI: 10.11646/zootaxa.5419.4.1, http://zenodo.org/record/10798799
Die Stadt München in ihren äußeren Beziehungen zur Universität; 1872
Creators: name: Destouches, Ernst von
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 2024

description: In: Münchener Gemeindezeitung, Festnummer zum Universitäts-Jubiläum, 1. August 1872. - Umschlagtitel: Münchener Gemeindezeitung, Festnummer zur vierhundertjährigen Jubelfeier der königlichen Ludwig-Maximilians-Universität in München
In-silico enhanced animal study of pulmonary artery pressure sensors: assessing hemodynamics using computational fluid dynamics
Creators: name: Brüning, Jan
name: Yevtushenko, Pavlo
name: Schlief, Adriano
name: Jochum, Tobias
name: Gijzen, Livia Van
name: Meine, Sonja
name: Romberg, Jan
name: Kuehne, Titus
name: Arndt, Andreas
name: Goubergrits, Leonid
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: heart failure
subject: pulmonary artery
subject: pressure sensor
subject: computational fluid dynamics
subject: wall shear stress
subject: oscillating shear index
subject: computed tomography
subject: porcine animal model
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: To assess whether in-silico models can be used to predict the risk of thrombus formation in pulmonary artery pressure sensors (PAPS), a chronic animal study using pigs was conducted. Computed tomography (CT) data was acquired before and immediately after implantation, as well as one and three months after the implantation. Devices were implanted into 10 pigs, each one in the left and right pulmonary artery (PA), to reduce the required number of animal experiments. The implantation procedure aimed at facilitating optimal and non-optimal positioning of the devices to increase chances of thrombus formation. Eight devices were positioned non-optimally. Three devices were positioned in the main PA instead of the left and right PA. Pre-interventional PA geometries were reconstructed from the respective CT images, and the devices were virtually implanted at the exact sites and orientations indicated by the follow-up CT after one month. Transient intra-arterial hemodynamics were calculated using computational fluid dynamics. Volume flow rates were modelled specifically matching the animals body weights. Wall shear stresses (WSS) and oscillatory shear indices (OSI) before and after device implantation were compared. Simulations revealed no relevant changes in any investigated hemodynamic parameters due to device implantation. Even in cases, where devices were implanted in a non-optimal manner, no marked differences in hemodynamic parameters compared to devices implanted in an optimal position were found. Before implantation time and surface-averaged WSS was 2.35 ± 0.47 Pa, whereas OSI was 0.08 ± 0.17, respectively. Areas affected by low WSS magnitudes were 2.5 ± 2.7 cm², whereas the areas affected by high OSI were 18.1 ± 6.3 cm². After device implantation, WSS and OSI were 2.45 ± 0.49 Pa and 0.08 ± 0.16, respectively. Surface areas affected by low WSS and high OSI were 2.9 ± 2.7 cm², and 18.4 ± 6.1 cm², respectively. This in-silico study indicates that no clinically relevant differences in intra-arterial hemodynamics are occurring after device implantation, even at non-optimal positioning of the sensor. Simultaneously, no embolic events were observed, suggesting that the risk for thrombus formation after device implantation is low and independent of the sensor position.
Comparison of procedural characteristics of percutaneous annuloplasty and edge-to-edge repair for the treatment of severe tricuspid regurgitation
Creators: name: Mattig, Isabel
name: Barbieri, Fabian
name: Kasner, Mario
name: Romero Dorta, Elena
name: Heinrich-Schüler, Anna Lisa
name: Zhu, Miry
name: Stangl, Karl
name: Landmesser, Ulf
name: Reinthaler, Markus
name: Dreger, Henryk
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2023
Subjects: subject: tricuspid regurgitation
subject: percutaneous annuloplasty
subject: transcatheter edge-to-edge repair
subject: procedural characteristics
subject: transcatheter valve intervention
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: In recent years, new interventional therapies for tricuspid regurgitation (TR) demonstrated their effectiveness in reducing TR severity and improving symptoms. Currently, tricuspid transcatheter edge-to-edge repair (T-TEER) and percutaneous annuloplasty are the most widely used techniques in Europe. In this retrospective study, we compared procedural characteristics and learning curves of both TR devices in a real-world cohort. Material and methods: Eligible patients with severe to torrential TR underwent either percutaneous annuloplasty or T-TEER as recommended by the local heart team. Patients with combined mitral and tricuspid interventions were excluded from the analysis. The study focused on procedural characteristics, TR reduction and learning curves. Results: A total of 122 patients underwent either percutaneous annuloplasty (n = 64) or T-TEER (n = 58) with a technical and device success rate of 98% and 97%, respectively. Reasons for technical failure included right coronary artery (RCA) dissection prior to percutaneous annuloplasty, and two single leaflet device attachments (SLDA) during T-TEER implantation. The mean improvement of TR severity was 2.4 ± 0.8 degrees after T-TEER and 2.5 ± 0.8 after percutaneous annuloplasty. T-TEER procedures were shorter in terms of both procedure time and radiation exposure, while percutaneous annuloplasty, although taking longer, showed a significant reduction in procedure time over the course of the analysed period. Conclusion: In summary, both interventional therapies reduce TR severity by approximately two degrees when used in the appropriate anatomy. The learning curve for annuloplasty group showed a significant decrease of procedure times.
Paralycus daeira Kolesnikov 2023
Creators: name: Norton, Roy A.
name: Ermilov, Sergey G.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Pediculochelidae
Paralycus
Paralycus daeira

description: Paralycus daeira Kolesnikov, OConnor, Ermilov & Klimov, 2023
Larva: Kolesnikov, OConnor, Ermilov & Klimov 2023 (Ds, FB, FGn, FLg, LSA)
Protonymph: Kolesnikov, OConnor, Ermilov & Klimov 2023 (Ds, FB, FGn, FLg, LSA)
Deutonymph: Kolesnikov, OConnor, Ermilov & Klimov 2023 (Ds, FB, LSA)
Tritonymph: Kolesnikov, OConnor, Ermilov & Klimov 2023 (Ds, FB, FGn, FLg, LSA)
description: Published as part of Norton, Roy A. & Ermilov, Sergey G., 2024, Catalogue of juvenile instars of oribatid mites (Acari: Oribatida) - the next decade (2014 - 2023), pp. 451-494 in Zootaxa 5419 (4) on page 454, DOI: 10.11646/zootaxa.5419.4.1, http://zenodo.org/record/10798799
Additional file 1: of High-throughput sequencing of RNAs isolated by cross-linking immunoprecipitation (HITS-CLIP) reveals Argonaute-associated microRNAs and targets in Schistosoma japonicum
Creators: name: Zhao, Jing
name: Luo, Rong
name: Xindong Xu
name: Zou, Ying
name: Qingfeng Zhang
name: Weiqing Pan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 60506 Virology

description: Primer sequences used in qPCR assays of S.japonicum miRNAs. (DOC 33 kb)
Elliptochthonius profundus Norton 1975
Creators: name: Norton, Roy A.
name: Ermilov, Sergey G.
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Arachnida
Sarcoptiformes
Elliptochthoniidae
Elliptochthonius
Elliptochthonius profundus

description: Elliptochthonius profundus Norton, 1975
Larva: Ermilov & Bayartogtokh 2022 (Ds, FB, FGn, FLg, LSA)
Protonymph: Ermilov & Bayartogtokh 2022 (Ds, FB, FLg, LSA)
Deutonymph: Ermilov & Bayartogtokh 2022 (Ds, FB, FLg, LSA)
Tritonymph: Ermilov & Bayartogtokh 2022 (Ds, FB, FGn, FLg, LSA)
description: Published as part of Norton, Roy A. & Ermilov, Sergey G., 2024, Catalogue of juvenile instars of oribatid mites (Acari: Oribatida) - the next decade (2014 - 2023), pp. 451-494 in Zootaxa 5419 (4) on page 454, DOI: 10.11646/zootaxa.5419.4.1, http://zenodo.org/record/10798799
Additional file 6: Table S4. of Synteny analysis in Rosids with a walnut physical map reveals slow genome evolution in long-lived woody perennials
Creators: name: Luo, Ming-Cheng
name: You, Frank
name: Pingchuan Li
name: Ji-Rui Wang
name: Tingting Zhu
name: Abhaya Dandekar
name: Leslie, Charles
name: Mallikarjuna Aradhya
name: McGuire, Patrick
name: Dvorak, Jan
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Numbers and percentages of walnut cdBES collinear with genes in the grape and poplar pseudomolecules located in SBs duplicated in the walnut genome. (DOCX 19.0 kb)