Entwicklung Und Implementierung Einer Tierversuchsfreien Strategie Zur Prüfung Der Lokalen Toxizität Von Chemikalien
Creators: name: Landsiedel, Robert
name: Kolle, Susanne N.
name: Bauch, Caroline
Publisher: name: Zenodo
Year: 2013
Subjects: local tolerance
alternative methods
animal testing
in vitro methods
award

description: Verleihung des 32. Tierschutz-Forschungspreises 2013 des Bundesministeriums für Ernährung, Landwirtschaft und Verbraucherschutz (BMELV) durch den Parlamentarischen Staatssekretär Peter Bleser
description: {"references": ["Bauch, Caroline, et al. \"Putting the parts together: combining in vitro methods to test for skin sensitizing potentials.\" Regulatory toxicology and pharmacology 63.3 (2012): 489-504.", "Mehling, Annette, et al. \"Non-animal test methods for predicting skin sensitization potentials.\" Archives of toxicology 86.8 (2012): 1273-1295.", "Kolle, Susanne N., et al. \"In-house validation of the EpiOcular\u2122 eye irritation test and its combination with the bovine corneal opacity and permeability test for the assessment of ocular irritation.\" Alternatives to Laboratory Animals-ATLA 39.4 (2011): 365.", "Bauch, Caroline, et al. \"Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals.\" Toxicology in Vitro 25.6 (2011): 1162-1168.", "Ramirez, Tzutzuy, et al. \"LuSens: a keratinocyte based ARE reporter gene assay for use in integrated testing strategies for skin sensitization hazard identification.\" Toxicology in Vitro 28.8 (2014): 1482-1497.", "G\u00f6tz, Christine, et al. \"Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte\u2010based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).\" Experimental dermatology 21.5 (2012): 358-363.", "Schrage, Arnhild, et al. \"The bovine corneal opacity and permeability test in routine ocular irritation testing and its improvement within the limits of OECD test guideline 437.\" Alternatives to Laboratory Animals-ATLA 39.1 (2011): 37.", "Kolle, Susanne N., et al. \"The EpiOcular\u2122 eye irritation test is the method of choice for the in vitro eye irritation testing of agrochemical formulations: Correlation analysis of EpiOcular eye irritation test and BCOP test data according to the UN GHS, US EPA and Brazil ANVISA classification schemes.\" ATLA 43 (2015): 181-98.", "Kolle, Susanne N., et al. \"Lacking applicability of in vitro eye irritation methods to identify seriously eye irritating agrochemical formulations: Results of bovine cornea opacity and permeability assay, isolated chicken eye test and the EpiOcular\u2122 ET-50 method to classify according to UN GHS.\" Regulatory Toxicology and Pharmacology 85 (2017): 33-47.", "Urbisch, Daniel, et al. \"Assessing skin sensitization hazard in mice and men using non-animal test methods.\" Regulatory Toxicology and Pharmacology 71.2 (2015): 337-351.", "Fabian, E., et al. \"Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro.\" Archives of toxicology 87.9 (2013): 1683-1696.", "Sauer, Ursula G., et al. \"Local tolerance testing under REACH: accepted non-animal methods are not on equal footing with animal tests.\" Altern Lab Anim 44.3 (2016): 281-99.", "Kolle, Susanne N., et al. \"Eye irritation testing of nanomaterials using the EpiOcular\u2122 eye irritation test and the bovine corneal opacity and permeability assay.\" Particle and fibre toxicology 13.1 (2015): 18.", "Kolle, Susanne N., et al. \"Erratum to \"Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies\"[Regul. Toxicol. Pharmacol.(2012) 402\u2013414].\" Regulatory Toxicology and Pharmacology 65.3 (2013): 366-378."]}