cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Language delay aggregates in toddler siblings of children with autism spectrum disorder
Creators: name: Hall, L P
name: Paterson, S J
name: Constantino, J N
name: Piven, J
name: Pruett, J R
name: Estes, A M
name: Botteron, K N
name: Eggebrecht, A T
name: Wolff, J J
name: Parish-Morris, J
name: Hazlett, H C
name: Zwaigenbaum, L
name: Elison, J T
name: Schultz, R T
name: Swanson, M R
name: Dager, S
name: Marrus, N
Publisher: name: BioMed Central
Year: 2018

description: Abstract
                Background
                Language delay is extremely common in children with autism spectrum disorder (ASD), yet it is unclear whether measurable variation in early language is associated with genetic liability for ASD. Assessment of language development in unaffected siblings of children with ASD can inform whether decreased early language ability aggregates with inherited risk for ASD and serves as an ASD endophenotype.
                Methods
                We implemented two approaches: (1) a meta-analysis of studies comparing language delay, a categorical indicator of language function, and language scores, a continuous metric, in unaffected toddlers at high and low familial risk for ASD, and (2) a parallel analysis of 350 unaffected 24-month-olds in the Infant Brain Imaging Study (IBIS), a prospective study of infants at high and low familial risk for ASD. An advantage of the former was its detection of group differences from pooled data across unique samples; an advantage of the latter was its sensitivity in quantifying early manifestations of language delay while accounting for covariates within a single large sample.
                Results
                Meta-analysis showed that high-risk siblings without ASD (HR-noASD) were three to four times more likely to exhibit language delay versus low-risk siblings without ASD (LR-noASD) and had lower mean receptive and expressive language scores. Analyses of IBIS data corroborated that language delay, specifically receptive language delay, was more frequent in the HR-noASD (n = 235) versus LR-noASD group (n = 115). IBIS language scores were continuously and unimodally distributed, with a pathological shift towards decreased language function in HR-noASD siblings. The elevated inherited risk for ASD was associated with lower receptive and expressive language scores when controlling for sociodemographic factors. For receptive but not expressive language, the effect of risk group remained significant even when controlling for nonverbal cognition.
                Conclusions
                Greater frequency of language delay and a lower distribution of language scores in high-risk, unaffected toddler-aged siblings support decreased early language ability as an endophenotype for ASD, with a more pronounced effect for receptive versus expressive language. Further characterization of language development is warranted to refine genetic investigations of ASD and to elucidate factors influencing the progression of core autistic traits and related symptoms.
Nitrate removal and environmental side-effects controlled by hydraulic residence time in woodchip bioreactors treating cold agricultural drainage water
Creators: name: Jéglot, Arnaud
name: Miranda-Velez, Jorge Federico
name: Plauborg, Finn
name: Elsgaard, Lars
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Marine Biology
subject: Virology

description: Denitrifying woodchip bioreactors (WBRs) remove nitrate (NO3−) from agricultural drainage water at field-scale, but their efficacy at cold temperatures remains uncertain. This study shows how hydraulic residence time (HRT) controls NO3− removal and environmental side-effects of WBRs at low water temperature under pilot-scale conditions with controlled operation of nine WBRs (94 dm3). Hydraulic properties were assessed by a bromide tracer test, and NO3− removal, emissions of nitrous oxide (N2O) and methane (CH4), and losses of dissolved organic carbon (DOC) were measured at HRTs of 5–30 h. Inlet NO3− concentrations were increasingly reduced at higher HRTs. The relationship between HRT and the efficiency (%) of NO3− removal was linear (Radj2 = 0.94), while the relationship between HRT and NO3− reduction rates (NRR) was logistic (Radj2 = 0.88). Gaseous emissions of N2O were equally low at HRTs of 10–30 h, but higher at 5 h (P < 0.05). Methane fluxes were small, but with consistent emissions at HRTs of 20–30 h and uptake at 5–15 h. HRT had limited effect on effluent DOC concentrations, but strong effect on mass losses that were five-fold higher (320 mg L−1) at the HRT of 5 h than at 30 h. In summary, at cold temperatures HRTs of ≤ 20 h resulted in suboptimal NRR, accelerating DOC losses, and increased risk of N2O losses at least below a threshold HRT of 5–10 h. HRTs of 20–30 h gave maximal NRR, smallest losses of DOC and N2O, but an increased risk of CH4 emissions.
ASPECTS OF THE MICROPALAEONTOLOGY AND STRATIGRAPHY OF CRETACEOUS SHELF CARBONATES FROM THE OMAN MOUNTAINS
Creators: name: SIMMONS, MICHAEL DEREK
Publisher: name: University of Plymouth
Year: 1990

description: Five outcrop sections (Wadi Mi'aidin, Wadi Bani Kharus, Jebel Madar, Jebel Madamar and Jebel Salak), exposing Thamama and Wasia Group sediments were sedimentologically logged and sampled. Thin sections of each of the Thamama Group samples were prepared for micropalaeontological and microfacies analysis. The foraminifera, calcareous algae and calpionellids in each sample were recorded in order to provide a means of biostratigraphic subdivision, and together with microfacies analysis and sedimentological observations made in the field, provide a means of elucidating the depositional environments of the Thamama Group in the study area. Correlation between outcrop sections has been attempted using a biozonation scheme developed in the course of this project, and also by graphic correlation techniques. The taxonomy of 39 genera including 56 species of key foraminifera, calcareous algae and calpionellids is reviewed in detail. A complete revision of Cretaceous Middle Eastern lithostratigraphic nomenclature is required. Some recommendations for such a revision are proposed. Within the Thamama Group, 13 biozones/subzones are recognised using the extinction and inception events for key taxa. Both biozonal correlation and graphic correlation demonstrate that most Thamama Group formations are diachronous and may also be condensed at some localities. Biostratigraphic studies demonstrate that in the Central Oman Mountains region the Thamama Group formations are of the following ages: The Rayda Formation is of Early Berriasian age. It possibly extends into the earliest Valanginian at some localities (eg. Wadi Bani Kharus). The Salil Formation is of Berriasian - Valanginian age, possibly Hauterivian in age in its upper part at some localities. The Habshan Formation is of Hauterivian age everywhere, with possible extension into the Late Valanginian in its IOWCT part The Lekhwair Formation is essentially of Hauterivian - Barremian age (often largely Hauterivian). The Kharaib Formation is of typically Late Barremian - Early Aptian age, whilst the Shuaiba Formation is of Early Aptian age. Thamama Group deposition took place on an initially downwarped carbonate ramp, prograding towards the Tethyan Ocean (towards the north and east). Offshore palaeowinds precluded the development of reefs, but an oolitic shoal was located at the margin of the ramp, at least during Hauterivian times.
Naturalization Records of Petitioner August Tappeiner
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1888

description: Naturalization records to become a citizen of the United States, as filled out and signed by: August Tappeiner Country of origin: Germany Age of petitioner: Unknown Occupation: Unknown City of residence at time of declaration: Unknown Date petition filed: 24 October 1888 Name of witness: Jacob Frey
The NRF2-mediated oxidative stress response pathway is associated with tumor cell resistance to arsenic trioxide across the NCI-60 panel
Creators: name: Jaspers, Ilona
name: Zou, Fei
name: Kesic, Matthew J
name: Smeester, Lisa
name: Fry, Rebecca
name: Liu, Qian
Publisher: name: BioMed Central Ltd
Year: 2010

description: Abstract Background Drinking water contaminated with inorganic arsenic is associated with increased risk for different types of cancer. Paradoxically, arsenic trioxide can also be used to induce remission in patients with acute promyelocytic leukemia (APL) with a success rate of approximately 80%. A comprehensive study examining the mechanisms and potential signaling pathways contributing to the anti-tumor properties of arsenic trioxide has not been carried out. Methods Here we applied a systems biology approach to identify gene biomarkers that underlie tumor cell responses to arsenic-induced cytotoxicity. The baseline gene expression levels of 14,500 well characterized human genes were associated with the GI50 data of the NCI-60 tumor cell line panel from the developmental therapeutics program (DTP) database. Selected biomarkers were tested in vitro for the ability to influence tumor susceptibility to arsenic trioxide. Results A significant association was found between the baseline expression levels of 209 human genes and the sensitivity of the tumor cell line panel upon exposure to arsenic trioxide. These genes were overlayed onto protein-protein network maps to identify transcriptional networks that modulate tumor cell responses to arsenic trioxide. The analysis revealed a significant enrichment for the oxidative stress response pathway mediated by nuclear factor erythroid 2-related factor 2 (NRF2) with high expression in arsenic resistant tumor cell lines. The role of the NRF2 pathway in protecting cells against arsenic-induced cell killing was validated in tumor cells using shRNA-mediated knock-down. Conclusions In this study, we show that the expression level of genes in the NRF2 pathway serve as potential gene biomarkers of tumor cell responses to arsenic trioxide. Importantly, we demonstrate that tumor cells that are deficient for NRF2 display increased sensitivity to arsenic trioxide. The results of our study will be useful in understanding the mechanism of arsenic-induced cytotoxicity in cells, as well as the increased applicability of arsenic trioxide as a chemotherapeutic agent in cancer treatment.
Declaration of Intention of Sylvester Borroni
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1919

description: Declaration of Intention to become a citizen of the United States, as filled out and signed by: Sylvester Borroni Applicant age:32Occupation: laborerCountry of Origin: ItalyDate of Birth: 2 March 1887Sailed to the US aboard the vessel: Didi Abruzzi City of residence at time of declaration: Elwood, NJDeclaration submitted and sworn on date:17 November 1919
Declaration of Intention of Richard Voigt
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1917

description: Declaration of Intention to become a citizen of the United States, as filled out and signed by: Richard Voigt Applicant age:33Occupation: DelicatessanCountry of Origin:GermanyDate of Birth: 23 October 1883Sailed to the US aboard the vessel: Nieterland City of residence at time of declaration: Atlantic City NJDeclaration submitted and sworn on date:19 March 1917
Integrative Management of Patchavaatham Post-Stroke: A Case Study Using Siddha Medicine
Creators: name: Jenifer Lancy A
name: Hariharan P
name: Arpita J
name: Shabu S
name: Nanma L
Publisher: name: gjrpublication
Year: 2024

description: Background: Patchavaatham, a condition akin to a cerebrovascular accident (stroke) in Siddha medicine, presents with symptoms such as hemiparesis, speech difficulties, and impaired gait. This case study examines the use of Siddha therapies, including internal medicines and external therapies like Thokkanam and Varma massage, in managing post-stroke sequelae.

Case Presentation: A patient presented with right-sided weakness, slurred speech, and difficulty walking following a cerebrovascular accident. The treatment approach included internal medications—Chandamarudha Chendhooram, Sangu Parpam, and Thaalisaadhi Chooranam—and external therapies focused on improving neuromuscular function. Over a 20-day period, the patient showed significant improvement in muscle strength, gait, and speech clarity.

Discussion: The integrative approach combining traditional Siddha medicine with physical therapy techniques proved beneficial in managing post-stroke symptoms, promoting nerve regeneration, and enhancing muscle strength. The patient's positive response to treatment highlights the potential of Siddha therapies as an adjunct in stroke rehabilitation.

Conclusion: Siddha therapies, particularly when combined with modern rehabilitation strategies, offer promising outcomes in managing neurological deficits post-stroke. Further studies, including randomized controlled trials, are necessary to validate these findings and establish standardized protocols.
Quantifying uncertainty in state and parameter estimation
Creators: name: Parlitz, Ulrich
name: Schumann-Bischoff, Jan
name: Luther, Stefan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Chaotic Dynamics (nlin.CD)
subject: FOS: Physical sciences

description: Observability of state variables and parameters of a dynamical system from an observed time series is analyzed and quantified by means of the Jacobian matrix of the delay coordinates map. For each state variable and each parameter to be estimated a measure of uncertainty is introduced depending on the current state and parameter values, which allows us to identify regions in state and parameter space where the specific unknown quantity can (not) be estimated from a given time series. The method is demonstrated using the Ikeda map and the Hindmarsh-Rose model.
description: 5 pages, 6 figures
Improving metabolic parameters of antipsychotic child treatment (IMPACT) study: rationale, design, and methods
Creators: name: Hazzard, Lindsey
name: Johnson, Jacqueline
name: Mabe, Micah
name: Scheer, Abigail
name: Hamer, Robert
name: Bethea, Terrence C
name: Alderman, Cheryl
name: Sikich, Linmarie
Publisher: name: BioMed Central Ltd
Year: 2013

description: Abstract Background Youth with serious mental illness may experience improved psychiatric stability with second generation antipsychotic (SGA) medication treatment, but unfortunately may also experience unhealthy weight gain adverse events. Research on weight loss strategies for youth who require ongoing antipsychotic treatment is quite limited. The purpose of this paper is to present the design, methods, and rationale of the Improving Metabolic Parameters in Antipsychotic Child Treatment (IMPACT) study, a federally funded, randomized trial comparing two pharmacologic strategies against a control condition to manage SGA-related weight gain. Methods The design and methodology considerations of the IMPACT trial are described and embedded in a description of health risks associated with antipsychotic-related weight gain and the limitations of currently available research. Results The IMPACT study is a 4-site, six month, randomized, open-label, clinical trial of overweight/obese youth ages 8–19 years with pediatric schizophrenia-spectrum and bipolar-spectrum disorders, psychotic or non-psychotic major depressive disorder, or irritability associated with autistic disorder. Youth who have experienced clinically significant weight gain during antipsychotic treatment in the past 3 years are randomized to either (1) switch antipsychotic plus healthy lifestyle education (HLE); (2) add metformin plus HLE; or (3) HLE with no medication change. The primary aim is to compare weight change (body mass index z-scores) for each pharmacologic intervention with the control condition. Key secondary assessments include percentage body fat, insulin resistance, lipid profile, psychiatric symptom stability (monitored independently by the pharmacotherapist and a blinded evaluator), and all-cause and specific cause discontinuation. This study is ongoing, and the targeted sample size is 132 youth. Conclusion Antipsychotic-related weight gain is an important public health issue for youth requiring ongoing antipsychotic treatment to maintain psychiatric stability. The IMPACT study provides a model for pediatric research on adverse event management using state-of-the art methods. The results of this study will provide needed data on risks and benefits of two pharmacologic interventions that are already being used in pediatric clinical settings but that have not yet been compared directly in randomized trials. Trial registration Clinical Trials.gov NCT00806234
СТРУКТУРНО-СЕМАНТИЧЕСКИЕ И МОТИВАЦИОННЫЕ ОСОБЕННОСТИ ЦВЕТООБОЗНАЧЕНИЙ ТОПОНИМОВ В АНГЛИЙСКОМ ЯЗЫКЕ
Creators: name: Рухсат Нормурод Кизи Рузимуродова
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: Ономасиология
вторичная номинация
топоним
этноним
цвет
цветообозначение
реалия.

description: Статья посвящена анализу и описанию структурных и семантических особенностей и классификации по мотивационной базе цветообозначений с топонимическими и этнонимическими компонентами в английском языке. Наряду с 11 базовыми понятиями цвета, в английском языке существует множество узуальных, относительно устойчивых и окказиональных номинации с компонентом топонимом или этнонимом для описания цветовых нюансов и оттенков, образованных с помощью процессов вторичной номинации.
Fatigue during treatment for hepatitis C virus: results of self-reported fatigue severity in two Phase IIb studies of simeprevir treatment in patients with hepatitis C virus genotype 1 infection
Creators: name: Evon, Donna M
Publisher: name: BioMed Central Ltd
Year: 2014

description: Abstract Background Fatigue is a common symptom of chronic hepatitis C virus (HCV) infection and a frequent side-effect of peginterferon/ribavirin (PR) therapy for HCV. This study evaluated the impact of adding the oral HCV NS3/4A protease inhibitor simeprevir to PR on patient-reported fatigue and health status among patients with chronic HCV genotype 1 infection enrolled in the Phase IIb PILLAR and ASPIRE trials [NCT00882908; NCT00980330]. Methods Treatment-naïve patients (PILLAR, n = 386) and treatment-experienced patients (ASPIRE, n = 462) were randomized to simeprevir plus PR (simeprevir/PR) or placebo plus PR (placebo/PR). In PILLAR, duration of PR treatment in the simeprevir/PR groups was determined using response-guided therapy (RGT) criteria. PR could be terminated at Week 24, instead of Week 48, if HCV RNA was <25 IU/mL by Week 4 and then undetectable at Weeks 12, 16, and 20. In both studies, patients completed the Fatigue Severity Scale (FSS) and EQ-5D quality-of-life questionnaire in their native language at baseline and throughout the studies up until Week 72. Results During the first 24 weeks of treatment, mean FSS total score was increased to a similar degree compared with baseline among patients receiving simeprevir/PR or placebo/PR in both studies indicating increased fatigue severity. Mean FSS scores returned to values comparable with baseline among patients receiving simeprevir/PR after Week 24 in PILLAR (after treatment completion for the majority of patients) and in ASPIRE (after Week 48), consistent with RGT enabling early termination of all treatment at Week 24 in 82.2% of simeprevir/PR-treated patients in the PILLAR study. Similar results were observed for EQ-5D, with simeprevir/PR-treated patients experiencing less time with worse health problems according to EQ-5D scores compared with placebo/PR groups in both studies, and more rapid improvement in health status associated with shorter treatment duration in the PILLAR study. Conclusions Combination of simeprevir with PR did not increase patient-reported fatigue severity or health status impairments beyond that reported by patients treated with PR alone. Many patients treated with simeprevir/PR returned to pretreatment fatigue and health status levels sooner due to increased treatment efficacy that enabled shorter duration of all therapy, compared with PR alone.
Quasi-SMILES as a basis to build up models of endpoints for nanomaterials
Creators: name: Toropova, Alla P.
name: Toropov, Andrey A.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Simplified molecular input-line entry system (SMILES) is a format for representing of the molecular structure. Quasi-SMILES is an extended format for representing molecular structure data and some eclectic data, which in principle could be applied to improve a model's predictive potential. Nano-quantitative structure-property relationships (nano-QSPRs) for energy gap (Eg, eV) of the metals oxide nanoparticles based on the quasi-SMILES give a predictive model for Eg, characterized by the following statistical quality for external validation set n=22, R2=0.83, RMSE=0.267.
Declaration of Intention of August Rinnen
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1920

description: Declaration of Intention to become a citizen of the United States, as filled out and signed by: August Rinnen Applicant age: 32Occupation: firemanCountry of Origin: GermanyDate of Birth: 18 January 1888Sailed to the US aboard the vessel: Faterland City of residence at time of declaration: Mizpah, NJDeclaration submitted and sworn on date: 18 February 1920
Declaration of Intention of Antonio Valento
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1925

description: Declaration of Intention to become a citizen of the United States, as filled out and signed by: Antonio Valento Applicant age:28Occupation: TailorCountry of Origin:ItalyDate of Birth: 11th September 1897Sailed to the US aboard the vessel: Prince Irene City of residence at time of declaration: Egg Harbor City NJDeclaration submitted and sworn on date: 6th November 1925
Risk factors for breast cancer characterized by the estrogen receptor alpha A908G (K303R) mutation
Creators: name: Tse, Chiu-Kit
name: Parrish, Eloise
name: Conway, Kathleen
name: Millikan, Robert C.
name: Edmiston, Sharon N
name: Tolbert, Dawn
Publisher: name: BioMed Central
Year: 2007

description: Abstract Introduction Estrogen is important in the development of breast cancer, and its biological effects are mediated primarily through the two estrogen receptors alpha and beta. A point mutation in the estrogen receptor alpha gene, ESR1, referred to as A908G or K303R, was originally identified in breast hyperplasias and was reported to be hypersensitive to estrogen. We recently detected this mutation at a low frequency of 6% in invasive breast tumors of the Carolina Breast Cancer Study (CBCS). Methods In this report, we evaluated risk factors for invasive breast cancer classified according to the presence or absence of the ESR1 A908G mutation in the CBCS, a population-based case-control study of breast cancer among younger and older white and African-American women in North Carolina. Of the 653 breast tumors evaluated, 37 were ESR1 A908G mutation-positive and 616 were mutation-negative. Results ESR1 A908G mutation-positive breast cancer was significantly associated with a first-degree family history of breast cancer (odds ratio [OR] = 2.69, 95% confidence interval [CI] = 1.15 to 6.28), whereas mutation-negative breast cancer was not. Comparison of the two case subgroups supported this finding (OR = 2.65, 95% CI = 1.15 to 6.09). There was also the suggestion that longer duration of oral contraceptive (OC) use (OR = 3.73, 95% CI = 1.16 to 12.03; P trend = 0.02 for use of more than 10 years) and recent use of OCs (OR = 3.63, 95% CI = 0.80 to 16.45; P trend = 0.10 for use within 10 years) were associated with ESR1 A908G mutation-positive breast cancer; however, ORs for comparison of the two case subgroups were not statistically significant. Hormone replacement therapy use was inversely correlated with mutation-negative breast cancer, but the effect on mutation-positive cancer was unclear due to the small number of postmenopausal cases whose tumors carried the mutation. Mutation-negative breast cancer was associated with several reproductive factors, including younger age at menarche (OR = 1.46, 95% CI = 1.09 to 1.94) and greater total estimated years of ovarian function (OR = 1.82, 95% CI = 1.21 to 2.74). Conclusion These preliminary results suggest that OCs may interact with the ESR1 A908G mutant receptor to drive the development of some breast tumors.
Hyperorthogonal well-folded Hilbert curves
Creators: name: Bos, Arie
name: Haverkort, Herman
Publisher: name: arXiv
Year: 2015
Subjects: subject: Computational Geometry (cs.CG)
subject: FOS: Computer and information sciences

description: R-trees can be used to store and query sets of point data in two or more dimensions. An easy way to construct and maintain R-trees for two-dimensional points, due to Kamel and Faloutsos, is to keep the points in the order in which they appear along the Hilbert curve. The R-tree will then store bounding boxes of points along contiguous sections of the curve, and the efficiency of the R-tree depends on the size of the bounding boxes---smaller is better. Since there are many different ways to generalize the Hilbert curve to higher dimensions, this raises the question which generalization results in the smallest bounding boxes. Familiar methods, such as the one by Butz, can result in curve sections whose bounding boxes are a factor $Ω(2^{d/2})$ larger than the volume traversed by that section of the curve. Most of the volume bounded by such bounding boxes would not contain any data points. In this paper we present a new way of generalizing Hilbert's curve to higher dimensions, which results in much tighter bounding boxes: they have at most 4 times the volume of the part of the curve covered, independent of the number of dimensions. Moreover, we prove that a factor 4 is asymptotically optimal.
description: Manuscript submitted to Journal of Computational Geometry. An abstract appeared in the 31st Int Symp on Computational Geometry (SoCG 2015), LIPIcs 34:812-826
Magnetic branes in Gauss-Bonnet gravity with nonlinear electrodynamics: correction of magnetic branes in Einstein-Maxwell gravity
Creators: name: Hendi, Seyed Hossein
name: Panahiyan, Shahram
name: Panah, Behzad Eslam
Publisher: name: arXiv
Year: 2015
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: In this paper, we are considering two first order corrections to both gravity and gauge sides of the Einstein-Maxwell gravity: Gauss-Bonnet gravity and quadratic Maxwell invariant as corrections. We obtain horizonless magnetic solutions by implying a metric which representing a topological defect. We analyze the geometric properties of the solutions and investigate the effects of both corrections, and find that these solutions may be interpreted as the magnetic branes. We study the singularity condition and find a nonsingular spacetime with a conical geometry. We also investigate the effects of different parameters on deficit angle of spacetime near the origin.
description: 10 pages with 9 figures
Associations of adult physical activity with perceived safety and police-recorded crime: the Multi-ethnic Study of Atherosclerosis
Creators: name: Evenson, Kelly
name: Rodriguez, Daniel
name: Wen, Fang
Publisher: name: BioMed Central Ltd
Year: 2012

description: Abstract Background Due to the inconsistent findings of prior studies, we explored the association of perceived safety and police-recorded crime measures with physical activity. Methods The study included 818 Chicago participants of the Multiethnic Study of Atherosclerosis 45 to 84 years of age. Questionnaire-assessed physical activity included a) transport walking; b) leisure walking; and c) non-walking leisure activities. Perceived safety was assessed through an interviewer-administered questionnaire. Police-recorded crime was assessed through 2-year counts of selected crimes (total and outdoor incivilities, criminal offenses, homicides) per 1000 population. Associations were examined using generalized estimating equation logistic regression models. Results Perceiving a safer neighborhood was positively associated with transport walking and perceiving lower violence was associated with leisure walking. Those in the lowest tertile of total or outdoor incivilities were more likely to report transport walking. Models with both perceived safety and police-recorded measures of crime as independent variables had superior fit for both transport walking and leisure walking outcomes. Neither perceived safety nor police-recorded measures of crime were associated with non-walking leisure activity. Conclusions Perceived and police-recorded measures had independent associations with walking and both should be considered in assessing the impact of neighborhood crime on physical activity.
Lösungsstrategien des Verkehrswachstums als Optionen der Verkehrswirtschaft
Creators: name: Heinze, G. Wolfgang
Publisher: name: Technische Universität Berlin
Year: 1992
Subjects: subject: 330 Wirtschaft
subject: 380 Handel, Kommunikation, Verkehr
subject: Verkehrswachstum
subject: Megatrends
subject: Wachstumslenkung
subject: Nachhaltigkeit
subject: traffic growth
subject: mega-trends
subject: growth management
subject: growth factors
subject: sustainability

description: Aus der Makroperspektive eines dynamischen Systems ist Verkehrswachstum normal. Um vergebliche Konfrontation zu vermeiden, fragt dieser Beitrag nach wirksamen und durchsetzbaren Maßnahmen kreativer Wachstumslenkung, um es umwelt-, sozial- und stadtverträglicher zu gestalten? Aus der Mikroperspektive der Akteure werden technische, zeitliche, biologische, psychologische, soziale, finanzielle und politische Wachstumsfaktoren sichtbar. Sie bieten zahlreiche Ansatzpunkte. Damit werden sie der Grundregel von Megatrends gerecht, mächtige Systemeffekte zu unterlaufen, indem man sie benutzt. Politisch gilt dies für Wirtschaftsgesellschaft mit einer dominierenden Autoindustrie in besonderem Maße.
description: From the macro perspective of a dynamic system traffic growth is normal. In order to avoid fruitless confrontation this paper asks for effective, enforceable measures for creative steering of traffic growth: to organize it in a socially attractive, environmentally friendly and city-compatible way. From the micro perspectives of the active players unexpected growth factors become visible: technological, temporary, biological, psychological, social, financial and political. They offer numerous opportunities and follow the basic rule for mega trends: to undermine them by utilizing them. This applies in particular to an economic society with a dominant car industry.
Localization and limit laws of a three-state alternate quantum walk on a two-dimensional lattice
Creators: name: Machida, Takuya
name: Chandrashekar, C. M.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Physics (quant-ph)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: A two-dimensional discrete-time quantum walk (DTQW) can be realized by alternating a two-state DTQW in one spatial dimension followed by an evolution in the other dimension. This was shown to reproduce a probability distribution for a certain configuration of a four-state DTQW on a two-dimensional lattice. In this work we present a three-state alternate DTQW with a parameterized coin-flip operator and show that it can produce localization that is also observed for a certain other configuration of the four-state DTQW and non-reproducible using the two-state alternate DTQW. We will present two limit theorems for the three-state alternate DTQW. One of the limit theorems describes a long-time limit of a return probability, and the other presents a convergence in distribution for the position of the walker on a rescaled space by time. We will also outline the relevance of these walks in physical systems.
description: 11 pages, 7 figures
Dye removal with emulsion liquid membrane: experimental design and response surface methodology
Creators: name: Benabela, Imene
name: Benderrag, Abdelkader
name: Haddou, Boumediene
name: Canselier, Jean Paul
name: Gourdon, Christophe
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Plant Biology

description: This work aims to removing anionic food dyes, Acid Red18 (E124) and Quinoline Yellow WS (E104), from their aqueous solutions. The Emulsion Liquid Membrane (ELM) technique was used. ELM consists of diluent (kerosene), nonionic surfactant (0.5 wt. % Triton X-45), Aliquat 336 as an extractant. Sulfuric acid (H2SO4) solution was used as an internal aqueous phase. The key parameters impacting the stability of liquid membrane and the efficiency of dye removal were investigated; Almost 98% of E124 at 50 mg/L are successfully extracted under optimum conditions. The extraction of a mixture of the two dyes at equal concentrations (25 mg/L) was conducted and their extraction showed more than 95% of efficiency. The experimental results of dye mixture (E124, E104) extraction were expressed by the following three quantities: The concentration of Triton X-45, the concentration of Aliquat 336, and the internal phase concentration of H2SO4, represented on three dimensional plots using the Box-Behnken design and the response surface methodology. For each of the parameters, the values of which were determined by experimental design, these results were subjected to empirical smoothing. The values, thus calculated, are consistent with the measurements.
Declaration of Intention of Ferdinand Nockel
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1920

description: Declaration of Intention to become a citizen of the United States, as filled out and signed by: Ferdinand Nockel Applicant age: 34Occupation: glass engraverCountry of Origin: GermanyDate of Birth: 18 January 1886Sailed to the US aboard the vessel: Lapland City of residence at time of declaration: Hammonton, NJDeclaration submitted and sworn on date: 16 March 1920
Declaration of Intention of Crescenzo Natale
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1919

description: Declaration of Intention to become a citizen of the United States, as filled out and signed by: Crescenzo Natale Applicant age: 32Occupation: laborerCountry of Origin: ItalyDate of Birth: 2 March 1887Sailed to the US aboard the vessel: Prinz Adalbert City of residence at time of declaration:Egg Harbor City, NJ Declaration submitted and sworn on date: 25 April 1919
Whole human genome proteogenomic mapping for ENCODE cell line data: identifying protein-coding regions
Creators: name: Wrobel, John A
name: Wang, Li
name: Xie, Ling
name: Gunawardena, Harsha P
name: Chen, Xian
name: Giddings, Morgan C.
name: Yu, Yanbao
Publisher: name: BioMed Central Ltd
Year: 2013

description: Abstract Background Proteogenomic mapping is an approach that uses mass spectrometry data from proteins to directly map protein-coding genes and could aid in locating translational regions in the human genome. In concert with the ENcyclopedia of DNA Elements (ENCODE) project, we applied proteogenomic mapping to produce proteogenomic tracks for the UCSC Genome Browser, to explore which putative translational regions may be missing from the human genome. Results We generated ~1 million high-resolution tandem mass (MS/MS) spectra for Tier 1 ENCODE cell lines K562 and GM12878 and mapped them against the UCSC hg19 human genome, and the GENCODE V7 annotated protein and transcript sets. We then compared the results from the three searches to identify the best-matching peptide for each MS/MS spectrum, thereby increasing the confidence of the putative new protein-coding regions found via the whole genome search. At a 1% false discovery rate, we identified 26,472, 24,406, and 13,128 peptides from the protein, transcript, and whole genome searches, respectively; of these, 481 were found solely via the whole genome search. The proteogenomic mapping data are available on the UCSC Genome Browser at http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=wgEncodeUncBsuProt. Conclusions The whole genome search revealed that ~4% of the uniquely mapping identified peptides were located outside GENCODE V7 annotated exons. The comparison of the results from the disparate searches also identified 15% more spectra than would have been found solely from a protein database search. Therefore, whole genome proteogenomic mapping is a complementary method for genome annotation when performed in conjunction with other searches.
Naturalization Records of Petitioner George Krumm
Creators: name: United States. Bureau Of Naturalization
Publisher: name: No Publisher Supplied
Year: 1890

description: Naturalization records to become a citizen of the United States, as filled out and signed by: George Krumm Country of origin: Germany Age of petitioner: Unknown Occupation: Unknown City of residence at time of declaration: Unknown Date petition filed: 8 April 1890 Name of witness: Joseph Bosch
СУРДОПЕДАГОГИКАДА АХБОРОТ ТЕХНОЛОГИЯЛАРИНИ ИШЛАБ ЧИҚИШ ВА ҚЎЛЛАШНИНГ ИСТИҚБОЛЛАРИ
Creators: name: Ферузахон Усмановна Қодирова
name: Зухра Шухратовна Cултанова
Publisher: name: Central Asian Research Journal for Interdisciplinary Studies (CARJIS)
Year: 2022
Subjects: кар ва заиф эшитувчи бола
таълим
коррекция
нутқ
машғулот
сифат
самарадорлик.

description: Ушбу мақолада сурдопедагогикада ахборот технологияларини ишлаб чиқиш ва қўллашнинг истиқболлари ва кар ва заиф эшитувчи болалар таълимида АКТ дан фойдаланишнинг долзарблиги хусусида маълумотлар келтирилади. Шунингдек, кар ва заиф эшитувчи болалар нутқини ривожлантиришда АКТ дан фойдаланишнинг имкониятлари санаб ўтилган.
Co-composting of digestate and garden waste with biochar: effect on greenhouse gas production and fertilizer value of the matured compost
Creators: name: Weldon, Simon
name: Rivier, Pierre-Adrien
name: Joner, Erik J.
name: Coutris, Claire
name: Budai, Alice
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Plant Biology

description: Biogas digestate is a nitrogen (N) rich waste product that has potential for application to soil as a fertilizer. Composting of digestate is recognized as an effective step to reduce potentially negative consequences of digestate application to soils. However, the structure of the digestate and the high N content can hinder effective composting. Biochar, which can be produced through the pyrolysis of waste biomass, has shown the potential to improve compost structure and increase N retention in soils. We studied how a high-temperature wood biochar affects the composting process, including greenhouse gas emissions, and the fertilizer value of the compost product including nutrient content, leachability and plant growth. The high Biochar dose (17% w/w) had a significantly positive effect on the maximum temperature (5°C increase vs. no biochar) and appeared to improve temperature stability during composting with less variability between replicates. Biochar addition reduced cumulative N2O emission by 65–70%, but had no significant effect on CO2 and CH4 emission. Biochar did not contribute to greater retention of nitrogen (N) contained in the digestate, but had a dilution effect on both N content and mineral nutrients. Fertilization with compost enhanced plant growth and nutrient retention in soil compared to mineral fertilization (NPK), but biochar had no additional effects on these parameters. Our results show that biochar improves the composting of digestate with no subsequent negative effects on plants.
Reporting Guidance for Trial Protocols of Social Science Interventions
Creators: name: Grant, Sean
Publisher: name: Open Science Framework
Year: 2022

description: Protocols improve reproducibility and accessibility of social science research. Given deficiencies in trial protocol quality, the SPIRIT Statement provides an evidence-based set of items to describe in protocols of clinical trials on biomedical interventions. However, such reporting guidance does not exist for trial protocols of social science interventions. This project will involve an online Delphi process to adapt and modify items of the SPIRIT Statement for guidance on reporting protocols of social science intervention trials. Participants will involve interdisciplinary stakeholders who develop or use trial protocols (i.e., researchers, journal editors, funders, IRB members, and social science registry coordinators). Participants will rate potential items on their importance for inclusion in a reporting checklist for trial protocols of social science interventions. Participants will also suggest revised wording for items and provide feedback on implementing the guideline for its successful adoption amongst social scientists. This Delphi process will identify consensus from a diverse panel of experts on items to include in guidance for trial protocol content for social science interventions—leading to the development of a useful tool for increasing the transparency of trial protocols and registries, and thereby increase the reproducibility of social science intervention research.
Mapping the knowledge and understanding of menarche, menstrual hygiene and menstrual health among adolescent girls in low- and middle-income countries
Creators: name: Patel, Sheila V
Publisher: name: BioMed Central
Year: 2017

description: Abstract Background Menstruation is a natural physiological process that requires proper management. Unlike other normal bodily processes, menstruation is linked with religious and cultural meanings that can affect the perceptions of young girls as well as the ways in which the adults in the communities around them respond to their needs. Objectives This review aims to answer the following questions: (1) how knowledgeable are adolescent girls in low- and middle-income countries about menstruation and how prepared are they for reaching menarche, (2) who are their sources of information regarding menstruation, (3) how well do the adults around them respond to their information needs, (4) what negative health and social effects do adolescents experience as a result of menstruation, and (5) how do adolescents respond when they experience these negative effects and what practices do they develop as a result? Methods Using a structured search strategy, articles that investigate young girls’ preparedness for menarche, knowledge of menstruation and practices surrounding menstrual hygiene in LMIC were identified. A total of 81 studies published in peer-reviewed journals between the years 2000 and 2015 that describe the experiences of adolescent girls from 25 different countries were included. Results Adolescent girls in LMIC are often uninformed and unprepared for menarche. Information is primarily obtained from mothers and other female family members who are not necessarily well equipped to fill gaps in girls’ knowledge. Exclusion and shame lead to misconceptions and unhygienic practices during menstruation. Rather than seek medical consultation, girls tend to miss school, self-medicate and refrain from social interaction. Also problematic is that relatives and teachers are often not prepared to respond to the needs of girls. Conclusion LMIC must recognize that lack of preparation, knowledge and poor practices surrounding menstruation are key impediments not only to girls’ education, but also to self-confidence and personal development. In addition to investment in private latrines with clean water for girls in both schools and communities, countries must consider how to improve the provision of knowledge and understanding and how to better respond to the needs of adolescent girls.
Acid mine drainage (AMD) treatment using galvanic electrochemical system Al–Cu
Creators: name: González-Hernández, Romel
name: Martínez-Miranda, Verónica
name: Linares-Hernández, Ivonne
name: Castillo-Suárez, Luis Antonio
name: Ceballos, Giovanni Sosa
name: Cortés-Martínez, Raúl
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Acid mine drainage was evaluated using a galvanic (GV) electrochemical system, Al–Cu (anode/cathode), based on a 32 factorial design. The factors analyzed were anodic area/volume ratios (A/V) of 0.037, 0.072, and 0.112 cm2/cm3, and treatment time from 0.25–8 h, and analyses were performed in duplicate with 11 degrees of freedom. The response variables were the total dissolved solids and concentrations of As, Cu, Co, Cr, Pb, Fe, Ni, and SO42−. The pH, electrical conductivity, and temperature were monitored during the process. Significant differences between treatments were determined by analysis of variance with Tukey’s test (p < 0.05) using Statgraphics Centurion XVI.I software. The results showed that a greater electrode surface, A/V ratio, and treatment time improved pollutant removal. The spontaneous reactions generated by the galvanic cell, through the current that flows owing to the potential difference between the Al and Cu electrodes, allows the removal of heavy metals, arsenic, and SO42− by coagulation and precipitation mechanisms. The removal efficiencies achieved were Cu (99.1%), As (76.6%), Ni (80.2%), Pb (83.6%), Cr (100%), Fe (93.71%), and 92.9% for sulfates. The X-ray diffraction and Raman analyses of the solid fraction indicated that cuprite was formed with a purity of 96%, and the recovery of Cu by the GV system may be a viable option for mining companies.