Additional file 1 of Development and internal validation of a model predicting severe maternal morbidity using pre-conception and early pregnancy variables: a population-based study in Ontario, Canada
Creators: name: Dayan, Natalie
name: Shapiro, Gabriel D.
name: Luo, Jin
name: Guan, Jun
name: Fell, Deshayne B.
name: Laskin, Carl A.
name: Basso, Olga
name: Park, Alison L.
name: Ray, Joel G.
Publisher: name: figshare
Year: 2021
Subjects: Medicine
Cell Biology
Pharmacology
Biotechnology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Science Policy

description: Additional file 1: Table S1. Variables used to define cohort entry and exclusion criteria, primary outcome, and variables considered for each clinical prediction model. Table S2. List of countries used to define World region of origin among immigrant women included in the study. Table S3. Adjusted odds ratio of maternal end-organ injury or death arising between 20 weeks’ gestation and up to 42 days after birth, in association with variables measured pre-pregnancy and in the index pregnancy prior to 20 weeks’ gestation. Table S4. Adjusted odds ratio of all-cause maternal death arising between birth and up to 365 days after birth, in association with variables measured pre-pregnancy and in the index pregnancy prior to 20 weeks’ gestation. Table S5. Adjusted odds ratio of maternal end-organ injury or death arising between 20 weeks’ gestation and up to 42 days after birth in association with variables measured in the index pregnancy prior to 20 weeks’ gestation. Table S6. Adjusted odds ratio of maternal end-organ injury or death arising between 20 weeks’ gestation and up to 42 days after birth in association with variables measured in the index pregnancy prior to 20 weeks’ gestation and pre-pregnancy. Table S7. Adjusted odds ratio of maternal end-organ injury or death arising between 20 weeks’ gestation and up to 42 days after birth in association with variables measured in the index pregnancy prior to 20 weeks’ gestation, pre-pregnancy, and in any previous pregnancy. Table S8. Baseline characteristics of the study population, according to missing BMI vs. non-missing BMI. Figure S1. Flow diagram of the creation of the study cohort. Figure S2. Receiver operating characteristic curve showing discrimination of the clinical prediction model for all-cause maternal death. Figure S3. a. Calibration plot of predicted (x-axis) and observed (y-axis) deciles of probability of acute end organ injury or death, entire cohort of 634,290 births. b. Calibration plot of predicted (x-axis) and observed (y-axis) deciles of probability of all-cause maternal death, entire cohort of 634,290 births. c. Calibration plot of predicted (x-axis) and observed (y-axis) deciles of probability of acute end organ injury or death, early index pregnancy factors, sub-cohort of 333,435 births among parous women. d. Calibration plot of predicted (x-axis) and observed (y-axis) deciles of probability of acute end organ injury or death, pre-pregnancy and early index pregnancy factors, sub-cohort of 333,435 births among parous women. e. Calibration plot of predicted (x-axis) and observed (y-axis) deciles of probability of acute end organ injury or death, pre-pregnancy, previous pregnancy, and early index pregnancy factors, sub-cohort of 333,435 births among parous women.