cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Sensing and recognizing affective touch in a furry zoomorphic object
Creators: name: Flagg, Anna
Publisher: name: University of British Columbia
Year: 2012

description: Over the last decade, the surprising fact has emerged that machines can possess therapeutic power. Due to the many healing qualities of touch, one route to such power is in haptic emotional interaction, which in turn requires sophisticated touch sensing and interpretation. We explore the development of affective touch gesture recognition technologies in the context of a furry artificial lap-pet, with the ultimate goal of creating therapeutic interactions by sensing human emotion through touch. We design, construct, and evaluate a low-cost, low-tech furry lap creature prototype equipped with 2 types of touch-sensing hardware. The first of these hardware types is our own design for a new type of touch sensor built with conductive fur, invented and developed as part of this research. The second is an existing design for a piezoresistive fabric pressure sensor, adapted to three dimensions for our robot-body context. Combining features extracted from the time-series data output of these sensors, we perform machine learning analysis to recognize touch gestures. In a study of 16 participants and 9 key affective gestures, our model averages 94% gesture recognition accuracy when trained on individuals, and 86% accuracy when applied generally across the entire set of participants. The model can also recognize who out of the 16 participants is touching the prototype with an accuracy of 79%. These results promise a new generation of emotionally intelligent machines, enabled by affective touch gesture recognition.
Additional file 1 of Prognostic factors of head and neck cutaneous squamous cell carcinoma: a systematic review
Creators: name: Lubov, Joshua
name: Labbé, Mathilde
name: Sioufi, Krystelle
name: Morand, Grégoire B.
name: Hier, Michael P.
name: Khanna, Manish
name: Sultanem, Khalil
name: Mlynarek, Alex M.
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: Science Policy

description: Additional file 1.
Initial data giving rise to naked singularities in spherically symmetric dust collapse
Creators: name: Ortiz, Néstor
Publisher: name: arXiv
Year: 2012
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The phase space corresponding to a particular four-parameter family of initial data for the gravitational collapse of a spherically symmetric dust cloud is investigated. In a certain limit of the parameters, this family reproduces the case of homogenous mass density -constant mass distribution- and zero initial velocity, while in another limit, it generates a globally naked singularity. We show that for initial data characterizing flat density profiles, as well as large initial velocities, the probability of forming a globally naked singularity is low.
description: 5 pages, 5 figures, prepared for the proceedings of the IX Workshop of the Gravitational and Mathematical Physics Division of the Mexican Physical Society. Refereed version
Context and Learning in Novelty Detection
Creators: name: McKeown, Kathleen
name: Schiffman, Barry
Publisher: name: Columbia University
Year: 2005
Subjects: Computer science
Information technology

description: We demonstrate the value of using context in a new-information detection system that achieved the highest precision scores at the Text Retrieval Conference's Novelty Track in 2004. In order to determine whether information within a sentence has been seen in material read previously, our system integrates information about the context of the sentence with novel words and named entities within the sentence, and uses a specialized learning algorithm to tune the system parameters.
Untersuchung der Wirkung von Sorafenib auf die hepatische Sternzelle bei Leberzirrhose
Creators: name: Kriesche, Franziska
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2019
Subjects: subject: 610

description: In früheren Studien wurde gezeigt, dass Sorafenib der Vasodilatation hepatischer Arterien bei der Leberzirrhose entgegenwirkt. Ziel der vorliegenden Arbeit war die Wirkung von Sorafenib auf die hepatischen Sternzellen (HSCs) in verschiedenen Zirrhosestadien zu untersuchen. Dazu wurden HSCs aus männlichen Wistar-Ratten, bei denen mittels Tetrachlormethan (CCl4) entweder eine beginnende oder eine fortgeschrittene Zirrhose induziert wurde, isoliert und anschließend mit Sorafenib inkubiert. Mittels Western Blot wurde die Expression des Angiogenesevermittlers VEGFA und seines Rezeptors (VEGF-R2), sowie von ERK und eNOS und deren phosphorylierten Formen bestimmt. Es konnte gezeigt werden, dass in zirrhotischen HSCs die VEGF-R2-Expression verstärkt war. In der beginnenden Zirrhose steigerte Sorafenib die eNOS-Expression und reduzierte die VEGF-R2-Expression. Im Gegensatz dazu erhöhte Sorafenib die VEGF-R2-Expression und verringerte die VEGF-Expression in der fortgeschrittenen Zirrhose. Sowohl die Steigerung der eNOS-Expression als auch die Reduktion der VEGF-R2-Expression durch Sorafenib konnte nur in der frühen Zirrhose beobachtet werden, was darauf hindeuten könnte, dass positive Effekte von Sorafenib auf die Fibrosierung der Leber in frühen Zirrhosestadien zu erwarten sind.
description: Preceding studies showed that Sorafenib inhibits the hepatic-arterial vasodilatation during liver cirrhosis. The aim of this study was to assess how Sorafenib influences hepatic stellate cells (HSCs) in different cirrhosis stages. Therefore, early or late stages of liver cirrhosis were induced in male Wistar rats by carbon tetrachlorid (CCl4) inhalation, respectively, before HSCs were isolated from the liver and treated with Sorafenib. The expression of the angiogenesis mediators VEGFA, VEGF-receptor 2 (VEGF-R2), as well as phosphorylated and non-phosphorylated ERK and eNOS, were analysed using Western Blots. In this study the VEGF-R2 expression in HSCs from cirrhotic livers was increased. Sorafenib increased eNOS expression in HSCs while it decreased VEGF-R2 expression in early cirrhosis. In contrast, the Sorafenib treatment of HSCs from late cirrhosis stages increased VEGF-R2 expression and decreased VEGFA expression. In conclusion, increased eNOS and decreased VEGF-R2 expression after Sorafenib treatment was exclusively detected in early cirrhosis. This indicates that Sorafenib positively influences liver cirrhosis only in early stages.
Characterization of Thin Pixel Sensor Modules Interconnected with SLID Technology Irradiated to a Fluence of 2$\cdot 10^{15}$\,n$_{\mathrm{eq}}$/cm$^2$
Creators: name: Weigell, P.
name: Andricek, L.
name: Beimforde, M.
name: Macchiolo, A.
name: Moser, H. -G.
name: Nisius, R.
name: Richter, R. -H.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Instrumentation and Detectors (physics.ins-det)
subject: FOS: Physical sciences

description: A new module concept for future ATLAS pixel detector upgrades is presented, where thin n-in-p silicon sensors are connected to the front-end chip exploiting the novel Solid Liquid Interdiffusion technique (SLID) and the signals are read out via Inter Chip Vias (ICV) etched through the front-end. This should serve as a proof of principle for future four-side buttable pixel assemblies for the ATLAS upgrades, without the cantilever presently needed in the chip for the wire bonding. The SLID interconnection, developed by the Fraunhofer EMFT, is a possible alternative to the standard bump-bonding. It is characterized by a very thin eutectic Cu-Sn alloy and allows for stacking of different layers of chips on top of the first one, without destroying the pre-existing bonds. This paves the way for vertical integration technologies. Results of the characterization of the first pixel modules interconnected through SLID as well as of one sample irradiated to $2\cdot10^{15}$\,\neqcm{} are discussed. Additionally, the etching of ICV into the front-end wafers was started. ICVs will be used to route the signals vertically through the front-end chip, to newly created pads on the backside. In the EMFT approach the chip wafer is thinned to (50--60)\,$μ$m.
description: Proceedings to PSD9
The ultrafilter number for singular cardinals
Creators: name: Garti, Shimon
name: Shelah, Saharon
Publisher: name: arXiv
Year: 2012
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: 03E05, 03E55

description: We prove the consistency of a singular cardinal $λ$ with small value of the ultrafilter number $u_λ$, and arbitrarily large value of $2^λ$.
description: 8 pages
Unoriented D-brane instantons
Creators: name: Bianchi, Massimo
name: Inverso, Gianluca
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We give a pedagogical introduction to D-brane instanton effects in vacuum configurations with open and unoriented strings. We focus on quiver gauge theories for unoriented D-branes at orbifold singularities and describe in some detail the Z_3 case, where both `gauge' and `exotic' instantons can generate non-perturbative super potentials, and the Z_5 case, where supersymmetry breaking may arise from the combined effect of `gauge' instantons and a FI D-term.
description: 12 pages, 1 figure. Proceedings of the "XVII European Workshop on String Theory 2011", Padova, Italy, 5-9 September 2011
title: สลากย้อม : จินตภาพใหม่สู่ศิลปะร่วมสมัย
Creators: name: สุเมธ จันทร์เพ็ญ
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
publisherIdentifierScheme: ROR
Year: 2024
Subjects: สลากย้อม
ศิลปะร่วมสมัย
ไทยอง
สามมิติ

description: Silpakorn University e-Journal (Social Sciences, Humanities, and Arts), 44, 5, 67-79
Path integral Monte Carlo with importance sampling for excitons interacting with an arbitrary phonon bath
Creators: name: Shim, Sangwoo
name: Aspuru-Guzik, Alán
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: Biological Physics (physics.bio-ph)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: The reduced density matrix of excitons coupled to a phonon bath at a finite temperature is studied using the path integral Monte Carlo method. Appropriate choices of estimators and importance sampling schemes are crucial to the performance of the Monte Carlo simulation. We show that by choosing the population-normalized estimator for the reduced density matrix, an efficient and physically-meaningful sampling function can be obtained. In addition, the nonadiabatic phonon probability density is obtained as a byproduct during the sampling procedure. For importance sampling, we adopted the Metropolis-adjusted Langevin algorithm. The analytic expression for the gradient of the target probability density function associated with the population-normalized estimator cannot be obtained in closed form without a matrix power series. An approximated gradient that can be efficiently calculated is explored to achieve better computational scaling and efficiency. Application to a simple one-dimensional model system from the previous literature confirms the correctness of the method developed in this manuscript. The displaced harmonic model system within the single exciton manifold shows the numerically exact temperature dependence of the coherence and population of the excitonic system. The sampling scheme can be applied to an arbitrary anharmonic environment, such as multichromophoric systems embedded in the protein complex. The result of this study is expected to stimulate further development of real time propagation methods that satisfy the detailed balance condition for exciton populations.
description: 16 pages, 5 figures
Additional file 1 of Anti-trypanosomal activity and DNA fingerprinting of fifteen Euphorbia species using ISSR and SCoT markers
Creators: name: El-Hawary, Seham S.
name: Lithy, Nadia M.
name: Amin, Elham
name: AbouZid, Sameh F.
name: Mohammed, Rabab
Publisher: name: figshare
Year: 2021
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1. The nucleotide sequence of each marker, The result of each marker & the dendrograms of SCoT, ISSR and their combination.
Additional file 1 of Exploring transformative learning for trainee pharmacists through interprofessional simulation: a constructivist interview study
Creators: name: Tallentire, Victoria R.
name: Kerins, Joanne
name: McColgan-Smith, Scott
name: Power, Ailsa
name: Stewart, Fiona
name: Mardon, Julie
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1.
Fundamental quantum optics experiments conceivable with satellites -- reaching relativistic distances and velocities
Creators: name: Rideout, David
name: Jennewein, Thomas
name: Amelino-Camelia, Giovanni
name: Demarie, Tommaso F.
name: Higgins, Brendon L.
name: Kempf, Achim
name: Kent, Adrian
name: Laflamme, Raymond
name: Ma, Xian
name: Mann, Robert B.
name: Martin-Martinez, Eduardo
name: Menicucci, Nicolas C.
name: Moffat, John
name: Simon, Christoph
name: Sorkin, Rafael
name: Smolin, Lee
name: Terno, Daniel R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: Physical theories are developed to describe phenomena in particular regimes, and generally are valid only within a limited range of scales. For example, general relativity provides an effective description of the Universe at large length scales, and has been tested from the cosmic scale down to distances as small as 10 meters. In contrast, quantum theory provides an effective description of physics at small length scales. Direct tests of quantum theory have been performed at the smallest probeable scales at the Large Hadron Collider, ${\sim} 10^{-20}$ meters, up to that of hundreds of kilometers. Yet, such tests fall short of the scales required to investigate potentially significant physics that arises at the intersection of quantum and relativistic regimes. We propose to push direct tests of quantum theory to larger and larger length scales, approaching that of the radius of curvature of spacetime, where we begin to probe the interaction between gravity and quantum phenomena. In particular, we review a wide variety of potential tests of fundamental physics that are conceivable with artificial satellites in Earth orbit and elsewhere in the solar system, and attempt to sketch the magnitudes of potentially observable effects. The tests have the potential to determine the applicability of quantum theory at larger length scales, eliminate various alternative physical theories, and place bounds on phenomenological models motivated by ideas about spacetime microstructure from quantum gravity. From a more pragmatic perspective, as quantum communication technologies such as quantum key distribution advance into Space towards large distances, some of the fundamental physical effects discussed here may need to be taken into account to make such schemes viable.
description: 34 pages, 9 figures. Journal version, modified to respond to numerous suggestions
Magnetic superspace groups and symmetry constraints in incommensurate magnetic phases
Creators: name: Perez-Mato, J. M.
name: Ribeiro, J. L.
name: Petricek, V.
name: Aroyo, M. I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Although superspace formalism has become the standard approach for the analysis of structurally modulated crystals, it has remained during the last thirty years almost unexplored as a practical tool to deal with magnetic incommensurate structures. This situation has recently changed with the development of new computer tools for magnetic phases based on this formalism. In this context we show here that, as in the case of nonmagnetic incommensurate systems, the concept of superspace symmetry provides a simple, efficient and systematic way to characterize the symmetry and rationalize the structural and physical properties of incommensurate magnetic materials. The method introduces significant advantages over the most commonly employed method of representation analysis for the description of the magnetic structure of a crystal. But, more importantly, in contrast with that method, it consistently yields and classifies all degrees of freedom of the system. The knowledge of the superspace group of an incommensurate magnetic material allows to predict its crystal tensor properties and to rationalize its phase diagram, previous to any appeal to microscopic models or mechanisms. This is especially relevant when the properties of incommensurate multiferroics are being studied. We present first a summary of the superspace method under a very practical viewpoint particularized to magnetic modulations. Its relation with the usual representation analysis is then analyzed in detail, with the derivation of important general rules for magnetic modulations with a single propagation vector. The power and efficiency of the formalism is illustrated with various selected examples, including some multiferroic materials.
Rapid Language Model Development Using External Resources for New Spoken Dialog Domains
Creators: name: Sarikaya, Ruhi
name: Gravano, Agustin
name: Gao, Yuqing
Publisher: name: Columbia University
Year: 2005
Subjects: Information technology
Computer science

description: This paper addresses a critical problem in deploying a spoken dialog system (SDS). One of the main bottlenecks of SDS deployment for a new domain is data sparseness in building a statistical language model. Our goal is to devise a method to efficiently build a reliable language model for a new SDS. We consider the worst yet quite common scenario where only a small amount (∼1.7K utterances) of domain specific data is available for the target domain. We present a new method that exploits external static text resources that are collected for other speech recognition tasks as well as dynamic text resources acquired from World Wide Web (WWW). We show that language models built using external resources can jointly be used with limited in–domain (baseline) language model to obtain significant improvements in speech recognition accuracy. Combining language models built using external resources with the in–domain language model provides over 20 % reduction in WER over the baseline in–domain language model. Equivalently, we achieve almost the same level of performance by having ten times as much in–domain data (17K utterances).
Additional file 3 of Exploring transformative learning for trainee pharmacists through interprofessional simulation: a constructivist interview study
Creators: name: Tallentire, Victoria R.
name: Kerins, Joanne
name: McColgan-Smith, Scott
name: Power, Ailsa
name: Stewart, Fiona
name: Mardon, Julie
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 3.
Weyl symmetric structure of QCD vacuum
Creators: name: Cho, Y. M.
name: Pak, D. G.
name: Zhang, P. M.
name: Zou, L. P.
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We consider Weyl symmetric structure of the classical vacuum in quantum chromodynamics. In the framework of formalism of gauge invariant Abelian projection we show that classical vacuums can be constructed in terms of Killing vector fields on the group SU(3). Consequently, homotopic classes of Killing vector fields determine the topological structure of the vacuum. In particular, the second homotopy group π_2(SU(3)/U(1)\times U(1)) describes all topologically non-equivalent vacuums which are classified by two topological numbers. For each given Killing vector field one can construct six vacuums forming Weyl sextet representation. An interesting feature of SU(3) gauge theory is that it admits a Weyl symmetric vacuum represented by a linear superposition of the six vacuums from the Weyl vacuum sextet. A non-trivial manifestation of Weyl symmetry is demonstrated on monopole solutions. We construct a family of finite energy monopole solutions in Yang-Mills-Higgs theory which includes Weyl monopole sextet. From the analysis of the classical vacuum structure and monopole solutions we conjecture that a similar Weyl symmetric vacuum structure can be realized in quantum theory.
description: 13 pages
Altocumulus: Harvesting Computational Resources from Devices at the Edge of the Cloud
Creators: name: Jung, YoungHoon
name: Szczodrak, Marcin K.
name: Neill, Richard W.
name: Carloni, Luca
Publisher: name: Columbia University
Year: 2013
Subjects: Computer science

description: The utilization of smart devices located at the edge of the cloud networks continues to accelerate, leading to new forms of heterogeneous cloud computing models. This trend has been influenced by two factors. First, the number of intelligent embedded devices in the cloud, such as smartphones and set-top boxes, has significantly increased. Second, cloud application executions like data processing and analytics are becoming more delegated from the clouds to the edge, thus making the transactions and communications in the cloud more local. We call Altocumulus a new class of heterogeneous cloud computing which occurs at the edge of the cloud where it harvests the resources of edge devices, typically embedded systems, to enhance application capabilities and performance. By reporting on a number of prior studies, we claim that Altocumulus is well positioned to support all main cloud-computing service models: IaaS, PaaS, and SaaS. We present our vision on how Altocumulus could develop in the context of other cloud computing technologies by discussing different models of computation delegation. We conclude by presenting possible use-case scenarios and open areas of research.
Shape memory polymer composite for adaptive components for orthosis and lower limb fracture fixators
Creators: name: Jeewantha, Janitha
Publisher: name: University of Southern Queensland
Year: 2023
Subjects: Composites, Shape memory polymers, Synthesis, Bisphenol A, Taguchi, Optimisation

description: Rapidly increasing engineering innovations have contributed invaluable new technologies to the biomedical field since the mid-20th century. This thesis is devoted to another vital development in the biomedical field with the invention of shape memory polymer (SMP) orthosis and lower limb fracture fixators. SMP is a smart material that can deform temporarily and recover its permanent shapes upon an external stimulus. This innovative product is an alternative to plaster of Paris casting which has been dominant in orthopaedic external fracture treatments. Bisphenol A base SMP was synthesised, and glass transition temperature was tailored to suit non-invasive biomedical applications. The manufacturing parameters of the product were optimised for the needs of orthopaedic bone immobilisation, using grey relational combined Taguchi analysis. The novel material is denoted as Ortho+, and it contains one layer of E-glass fibre with 0.4 wt% of TiO2 . The concept was successfully proved with, a lower limb leg cylindrical cast using Ortho+ on a mannequin in less than 10 mins. The Ortho+ SP is lightweight, has less setting time, allows multiple alterations and optimal air circulation. Ortho+ can be reused after disinfection; thus, it is ideal for first aid treatment where the required medical facilities are not freely available. This research has successfully established ground-breaking knowledge in the material development framework and opened up a new window to replace traditional orthopaedic materials with Ortho+ to manufacture next-generation orthosis and fracture fixators.
Additional file 2 of Exploring transformative learning for trainee pharmacists through interprofessional simulation: a constructivist interview study
Creators: name: Tallentire, Victoria R.
name: Kerins, Joanne
name: McColgan-Smith, Scott
name: Power, Ailsa
name: Stewart, Fiona
name: Mardon, Julie
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 2.
Herded Gibbs sampling
Creators: name: Fang, Jing
Publisher: name: University of British Columbia
Year: 2012

description: The Gibbs sampler is one of the most popular algorithms for inference in statistical models. In this thesis, we introduce a herding variant of this algorithm that is entirely deterministic. We demonstrate, with simple examples, that herded Gibbs exhibits better convergence behavior for approximating the marginal distributions than Gibbs sampling. In particular, image denoising exemplifies the effectiveness of herded Gibbs as an inference technique for Markov Random Fields (MRFs). Also, we adopt herded Gibbs as the inference engine for Conditional Random Fields (CRFs) in Named Entity Recognition (NER) and show that it is competitive with the state of the art. The conclusion is that herded Gibbs, for graphical models with nodes of low degree, is very close to Gibbs sampling in terms of the complexity of the code and computation, but that it converges much faster.
Evolutionary genetics of a bizarre adaptation : elongated forelegs of South African Rediviva bees as an adaptation to their Diascia flower hosts
Creators: name: Kahnt, Belinda
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2019
Subjects: subject: 570

description: In meiner Dissertation untersuchte ich die Evolution und Genetik eines bizarren Merkmals, verlängerte Vorderbeine, in südafrikanischen Rediviva Bienen. Rediviva Weibchen evolvierten lange Beine um Öl aus den Spornen ihrer Hauptwirtspflanze Diascia zu sammeln. Die Vorderbeinlänge (VBL) von Rediviva variiert nicht nur inter- sondern auch intraspezifisch, wobei diese signifikant mit der Spornlänge von Diascia korreliert ist, d.h. auf Koevolution hinweist. Meine Arbeit deutet auf eine rasche Evolution der VBL und auf mehrere Ursprünge für lange Vorderbeine hin. Die VBL beeinflusst jedoch nicht die genetische Differenzierung von Rediviva Populationen, die stark durch Gendrift geprägt wird, wie eine geringe genetische Diversität und Bottlenecks suggerierten. Mehrere Gene, u.a. Kandidaten zur VBL Regulation, stehen zudem unter Selektion. Obwohl Rediviva und Diascia koevolvieren erfolgt eine Ko-Speziation scheinbar selten. Hingegen scheint der Wechsel von Rediviva Bestäubern häufig die Artbildung von Diascia anzutreiben. Meine Arbeit erlaubt es die Evolution und Diversifikation von Pflanzen-Bestäuber-Interaktionen besser zu verstehen.
description: In my PhD thesis I studied the evolution and genetics of a bizarre trait, elongated forelegs, in South African Rediviva bees. Female Rediviva have evolved extended forelegs in order to collect oil from the spurs of their main host plant Diascia. Interestingly, Rediviva foreleg length (FLL) shows not only inter- but also intraspecific variation, which seems to be significantly correlated with Diascia spur length, indicating coevolution. My studies suggested several independent origins of long forelegs and that FLL is a rapidly evolving trait. However, I did not find that FLL influences the genetic differentiation of Rediviva populations, which seem to be strongly affected by genetic drift as indicated by a low genetic diversity and signatures of bottleneck events. Several genes, including candidate genes regulating FLL, were also suggested to experience selection. Moreover, although Rediviva and Diascia are coevolving, they rarely seem to cospeciate. I rather found that shifts between Rediviva pollinators frequently drive Diascia speciation. Overall, my studies help to understand the evolution and diversification of plant-pollinator-interactions.
title: Driver Monitoring mit Fokus auf Vigilanz
title: Fahrerzustandserkennung durch Fusion von physiologischen Daten
titleType: AlternativeTitle
Creators: name: Hugenroth, Alexander
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: Aufmersamkeit
subject: Auto
subject: Automatisiertes Fahren
subject: Fahrermodell
subject: Fahrerzustand
subject: 620
subject: Autonomes Fahrzeug

description: Die Anzahl teilautomatisierter Fahrfunktionen wächst stetig, wobei in den meisten Fällen die Aufmerksamkeit des Fahrers gefordert wird. Bei der Müdigkeitserkennung wird der Zustand des Fahrers durch das Festhalten des Lenkrads oder Blicküberprüfung festgestellt. Das Festhalten des Lenkrads entfällt bei höheren teilautomatisierten Systemen. Das Ziel dieser Arbeit ist es auf Grundlage von mehreren physiologischen Merkmalen ein präziseres Modell der Fahreraufmerksamkeit zu entwickeln, sodass die geforderte Reaktionsbereitschaft (Vigilanz) besser identifiziert werden kann. Hierzu werden die Daten aus Fahrversuchen in einem Simulator genutzt, um neben den psychologischen Erkenntnissen auch zwei verschiedene Modelle mit unterschiedlichen Fusionsmethoden zu entwickeln. Die Modelle, auf Basis von künstlichen neuronalen Netzen, werden mit verschiedenen Datensätzen ausgewertet, sodass zusätzlich zu der Funktion unter normalen Bedingungen auch eine Ausfallsituation berücksichtigt wird.
Additional file 4 of Exploring transformative learning for trainee pharmacists through interprofessional simulation: a constructivist interview study
Creators: name: Tallentire, Victoria R.
name: Kerins, Joanne
name: McColgan-Smith, Scott
name: Power, Ailsa
name: Stewart, Fiona
name: Mardon, Julie
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 4.
From biomass to levulinic acid: Inline reaction monitoring by MIR spectroscopy in harsh conditions of a thermochemical lignocellulosic biorefinery
Creators: name: Echtermeyer, Alexander Walter Wilhelm
name: Viell, Jörn
Publisher: name: RWTH Aachen University
Year: 2023

description: 6. European Conference on Process Analytics and Control Technology, EuroPACT 2023, Copenhagen, Denmark, 1 May 2023 - 10 May 2023
The M31 Velocity Vector. III. Future Milky Way-M31-M33 Orbital Evolution, Merging, and Fate of the Sun
Creators: name: van der Marel, Roeland P.
name: Besla, Gurtina
name: Cox, T. J.
name: Sohn, Sangmo Tony
name: Anderson, Jay
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We study the future orbital evolution and merging of the MW-M31-M33 system, using a combination of collisionless N-body simulations and semi-analytic orbit integrations. Monte-Carlo simulations are used to explore the consequences of varying the initial phase-space and mass parameters within their observational uncertainties. The observed M31 transverse velocity implies that the MW and M31 will merge t = 5.86 (+1.61-0.72) Gyr from now, after a first pericenter at t = 3.87 (+0.42-0.32) Gyr. M31 may (probability p=41%) make a direct hit with the MW (defined here as a first-pericenter distance less than 25 kpc). Most likely, the MW and M31 will merge first, with M33 settling onto an orbit around them. Alternatively, M33 may make a direct hit with the MW first (p=9%), or M33 may get ejected from the Local Group (p=7%). The MW-M31 merger remnant will resemble an elliptical galaxy. The Sun will most likely (p=85%) end up at larger radius from the center of the MW-M31 merger remnant than its current distance from the MW center, possibly further than 50 kpc (p=10%). The Sun may (p=20%) at some time in the next 10 Gyr find itself moving through M33 (within 10 kpc), but while dynamically still bound to the MW-M31 merger remnant. The arrival and possible collision of M31 (and possibly M33) with the MW is the next major cosmic event affecting the environment of our Sun and solar system that can be predicted with some certainty. (Abridged)
description: 58 pages, 16 figures, to be published in ApJ. Version with high resolution figures and N-body movies available at http://www.stsci.edu/~marel/M31 . Press materials, graphics, and visualizations available at http://hubblesite.org/newscenter/archive/releases/2012/20
title: จากเมืองพระบางสู่เมืองนครสวรรค์ในมุมมองหลักฐานทางประวัติศาสตร์
Creators: name: พิมพ์อุมา ธัญธนกุล
Publisher: name: สำนักงานบริหารการวิจัย นวัตกรรมและการสร้างสรรค์
publisherIdentifierScheme: ROR
Year: 2024
Subjects: พระบาง
เมืองนครสวรรค์
หลักฐานทางประวัติศาสตร์

description: Silpakorn University e-Journal (Social Sciences, Humanities, and Arts), 44, 5, 80-89
Diffeomorphism Algebra Structure and Membrane Theory
Creators: name: Hoppe, Jens
name: Hynek, Mariusz
Publisher: name: arXiv
Year: 2011
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Explicit structure constants are calculated for certain Lie algebras of vectorfields on 2-dimensional compact manifolds.
description: 7 pages
Anti-inflammatorische Strategien beim hämorrhagischen Schock in der Ratte
Creators: name: Klappstein, Cathleen
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2019
Subjects: subject: 610

description: Diese Studie wurde an einem druckkontrollierten Schockmodell an Ratten durchgeführt. Es erfolgte die Einteilung in drei Versuchsgruppen: eine Sham-Gruppe, eine Schock + Vehikel-Gruppe sowie eine Schock + Medikament-Gruppe. BAY 11-7085 wurde 15 Minuten vor Reperfusion intraarteriell, Pioglitazone 12-16 h vor Versuchsbeginn intraperitoneal appliziert. Die narkotisierten Tiere wurden durch Entnahme von Blut in einen hämorrhagischen Schock versetzt. Nach insgesamt 1 Stunde erfolgte die Reperfusion des entnommenen Blutes. Nach dem Tod der Tiere wurden Leber, Lunge, Herz und Niere entnommen und Western Blots angefertigt sowie die Myeloperoxidaseaktivität bestimmt. Für BAY 11-7085 zeigte sich die Stabilisierung des MAD und des Hämatokrits. Für Pioglitazone zeigte sich eine signifikante Verbesserung des Outcome sowie die Stabilisierung von MAD und HF. Beide Medikamente zeigten antiinflammatorische Effekte. Insgesamt scheint Pioglitazone jedoch besser protektiv als BAY zu wirken.
description: This study was performed on a pressure-controlled shock model with rats. The animals were rationed into the following groups: sham-group, shock + vehicle, shock + medicine group. BAY 11-7085 was given intravascular 15 minutes before reperfusion, Pioglitazone was given intraperitoneal 12-16 hours before experimental procedere. Blood was remove from the anesthetized animals for 1 hour, after that, the blood was returned. After dying the liver, lungs, heart and kidneys were removed for performing western blots and for assignment of myeloperoxidase-activity. With BAY 11-7085 examined animals showed a stabilization of MAD und hematocrit. With Pioglitazone examined animals showed a significant improvement from outcome and stabilization of MAD and heart rate. Both drugs pointed anti-inflammatory effects. In summary Pioglitazone seems to act more protective than BAY in hemorrhagic shock.
Additional file 1 of Experiences of renal healthcare practitioners during the COVID-19 pandemic: a multi-methods approach
Creators: name: Mc Keaveney, Clare
name: Reid, Joanne
name: Carswell, Claire
name: Bonner, Ann
name: de Barbieri, Ilaria
name: Johnston, William
name: Maxwell, Alexander P.
name: O’Riordan, Julien
name: Strini, Veronica
name: Walsh, Ian
name: Noble, Helen
Publisher: name: figshare
Year: 2021
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1.
Inline Monitoring of Acid Dissociation by Indirect Hard Modeling
Creators: name: Echtermeyer, Alexander Walter Wilhelm
name: Marks, Caroline
name: Mitsos, Alexander
name: Viell, Jörn
Publisher: name: RWTH Aachen University
Year: 2023

description: 7. International Conference "Fuel Science - From Production to Propulsion", FSC 2019, Aachen, Germany, 13 May 2019 - 15 May 2019
Improving Multilingual Summarization: Using Redundancy in the Input to Correct MT errors
Creators: name: McKeown, Kathleen
name: Siddharthan, Advaith
Publisher: name: Columbia University
Year: 2005
Subjects: Computer science
Information technology

description: In this paper, we use the information redundancy in multilingual input to correct errors in machine translation and thus improve the quality of multilingual summaries. We consider the case of multidocument summarization, where the input documents are in Arabic, and the output summary is in English. Typically, information that makes it to a summary appears in many different lexical-syntactic forms in the input documents. Further, the use of multiple machine translation systems provides yet more redundancy, yielding different ways to realize that information in English. We demonstrate how errors in the machine translations of the input Arabic documents can be corrected by identifying and generating from such redundancy, focusing on noun phrases.
State Policies to Achieve the Dream in Five States: An Audit of State Policies to Aid Student Access to and Success in Community Colleges in the First Five Achieving the Dream States
Creators: name: Dougherty, Kevin J.
name: Kerrigan, Monica Reid
name: Nienhusser, Helmut Kenny
Publisher: name: Columbia University
Year: 2006
Subjects: Education and state
School management and organization
Community college students--Education
Community colleges

description: This report presents the findings of an audit of state policies affecting access to, and success in, community colleges in five states—Florida, New Mexico, North Carolina, Texas, and Virginia. Given recent local and state initiatives to implement programs to improve student access and success, this report explores the existence of key policies relating to tuition, student aid, open door admissions, remedial (or developmental education), transfer, performance accountability, and a number of other key areas. Recommendations for future state policy are also discussed.
From structural plasticity to the development of next-generation inhibitors to overcome drug-resistant GIST
Creators: name: Schulz, Tom
Publisher: name: TU Dortmund
Year: 2024
Subjects: subject: Cancer
subject: GIST
subject: Drug resistance
subject: Kinase inhibitors
subject: Covalent inhibitors
subject: Structure-based drug design
subject: 570
subject: 540
subject: Krebs

description: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract, primarily driven by activating mutations in the receptor tyrosine kinases KIT and PDGFRA. While tyrosine kinase inhibitors (TKIs) have improved treatment outcomes, their efficacy is often compromised by acquired resistance mutations and dose-limiting toxicities. This highlights the need for next-generation inhibitors with improved potency and selectivity. A detailed structural understanding of the kinase's ability to adopt different conformations and the impact of (resistance) mutations is crucial for the development of novel small molecules with improved efficacy. This work elucidates the molecular basis of drug resistance in GIST, focusing on mutations within the ATP-binding pocket and activation loop of the kinase domain. Through in-depth structural analysis and structure-activity relationship (SAR) studies, a previously undescribed, targetable sub-pocket in KIT and PDGFRA was identified. Located between two key regulatory elements, the Gly-rich loop and the αC-helix, this pocket - termed the Gα-pocket - represents a novel target for inhibitor design. These structural insights guided the design and synthesis of novel kinase inhibitors, enabling the identification of key pharmacophoric features necessary to overcome resistance. Given the success of covalent inhibitors such as osimertinib and ibrutinib in the treatment of otherwise drug-resistant cancers, this work explores their untapped potential in GIST to overcome resistance while improving potency and selectivity. In summary, this work lays the foundation for next-generation inhibitors to address the pressing challenge of drug resistance in GIST.
Counting solutions from finite samplings
Creators: name: Huang, Haiping
name: Zhou, Haijun
Publisher: name: arXiv
Year: 2011
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Information Theory (cs.IT)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We formulate the solution counting problem within the framework of inverse Ising problem and use fast belief propagation equations to estimate the entropy whose value provides an estimate on the true one. We test this idea on both diluted models (random 2-SAT and 3-SAT problems) and fully-connected model (binary perceptron), and show that when the constraint density is small, this estimate can be very close to the true value. The information stored by the salamander retina under the natural movie stimuli can also be estimated and our result is consistent with that obtained by Monte Carlo method. Of particular significance is sizes of other metastable states for this real neuronal network are predicted.
description: 9 pages, 4 figures and 1 table, further discussions added
HealthyCloud Strategic Agenda for the Health Research Innovation Cloud (HRIC) - First Draft
Creators: name: Canham, Steve
name: Ohman, Christian
name: Demotes-Mainard, Jacques
name: Panagiotopoulou, Maria
Publisher: name: Zenodo
Year: 2022
Subjects: health data, distributed computing, FAIR data,

description: This document is the first draft of the Strategic Agenda to towards the construction of the Health Research and Innovation Cloud (HRIC). The HRIC is intended to be one of the cornerstones of European Health Data Space, specifically on its incarnation devoted to secondary use of health data, building on top of existing initiatives such as the European Open Science Cloud (EOSC) building blocks. NOTE: this draft has not been approved by the European Commision and reflects only the opinions of the HealthyCloud Consortium.
Non-singular Brans-Dicke cosmology with cosmological constant
Creators: name: Tretyakova, Darya
name: Shatskiy, Alexander
name: Novikov, Igor
name: Alexeyev, Stanislav
Publisher: name: arXiv
Year: 2011
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider Brans-Dicke cosmology with cosmological constant with negative w parameter and an arbitrary (in general non-vanishing) scale factor at the Big Bang. The field equations describe the flat universe, current observational values for Hubble constant H and deceleration parameter q play a role of initial conditions. In order to solve field equations we adopt the approach of Uehara and Kim (1982). They considered only positive values of w, hence our solution is a new one and has not been described in their paper. Our main result is that unlike the standard cosmology the scale factor may not vanish in it's evolution back in time. In other words our model displays a cosmological bounce and avoids the initial singularity. The formula for the scale factor, leading to the bounce, is only valid for the dust-filled universe and hence cannot be adequate for the hot stage in the early universe when the bounce happens. So, the results of this paper are only qualitative in nature and must be used to obtain initial values for the hot stage of the unverse when one considers the evolution back in time.
description: 12 pages, 1 figure
Biochemical analysis of Arabidopsis thaliana IQ67-Domain Protein 1 and related proteins
Creators: name: Pflug, Friedrich Paul
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2019
Subjects: subject: 572

description: Reverse genetische Analysen zeigten, dass IQDs höchstwahrscheinlich bei der Regulation der Zellform involviert sind und damit auch die Organ- bzw. Pflanzengestalt beeinflussen. Obwohl die IQD-Genfamilie in verschiedenen Pflanzengattungen untersucht wurde, ist über die biologische Rolle und über die molekulare Funktion wenig bekannt. Diese Arbeit zeigt, dass IQD1 und generell IQD-Proteine unabhängig vom Ca2+-Status mit CaM interagieren können. Es wird weiterhin gezeigt, dass IQD-Proteine direkt mit KLCRs und mit MT in vitro interagieren sowie KLCRs und CaM gleichzeitig an MT in planta rekrutieren können. Erste Hinweise zeigen, dass KLCR-Proteine mit Ca2+-CaM interagieren und IQD-abhängig zu Apo-CaM rekrutiert werden können. In vitro und in planta Ansätze deuten darauf hin, dass IQD- und KLCR-Proteine durch Mitogen activated Protein Kinases (MPK) phosphoryliert werden und das die Lokalisation von IQD1 durch diese Phosphorylierungen reguliert wird. Zusammengefasst unterstützen die Ergebnisse dieser Arbeit die Hypothese, dass IQD-Proteine als Gerüstproteine fungieren, indem sie die CaM-vermittelte Ca2+ Signalweitergabe an spezifischen Stellen der Zelle verankern und somit eine schnelle und lokale molekulare Antwort zu ermöglichen.
description: Reverse genetic analysis revealed that IQDs most likely are involved in regulating cell shape and therefore influence organ morphology. Although studied in many organisms little is known about their biological role or molecular function. This study shows that IQD1 and IQD proteins in general interact with Ca2+- and Apo-CaM. We further provide evidence that IQD proteins directly interact with KLCR proteins as well as with MTs in vitro and can recruit KLCRs and CaM to the MTs simultaneously in planta. We found that KLCR proteins are Ca2+-CaM binding proteins and are recruited to Apo-CaM in an IQD dependent fashion. In vitro and in planta experiments reveal that IQD and KLCR proteins are targets of Mitogen Activated Protein Kinases (MPK) and that the localization of IQD1 might be regulated by MPK derived phosphorylation. Collectively this study supports the hypothesis that IQD proteins act as scaffolding proteins mediating CaM dependent Ca2+ signaling at specific sites at the cell the ensure a fast and local response.