cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Synthesis and Biological Evaluation of Novel Nitrogen Containing 6 and 7 Membered Ring Heterocyclic Compounds
Creators: name: Hussain, Idhnan Abas
Publisher: name: University of Hertfordshire
Year: 2014
Subjects: α,β unsaturated carbonyl
piperidone
tropan-3-one
benzothiazine
antifungal
cytotoxicity

description: Literature reports have previously shown interesting antimicrobial activities of compounds containing the α,β unsaturated carbonyl function and various piperidone and tropanone derivatives have attracted interest. A series of ring substituted N-piperidone dieneones and a novel parent tropan-3-one were synthesized and characterized. Novel compounds along with a previously synthesized library of 1,2-benzothiazines were examined for their antifungal properties. The tropan-3-one and benzothiazines proved to be ineffective inhibitors of Saccharomyces cerevisiae growth (<20%). Dieneones of N-piperidone and N-methyl piperidone showed a wide spectrum of activities whereby the free bases are marginally more potent than their respective hydrochloride salts. Based on their potencies against S. cerevisiae a subset of dieneones were screened against Candida albicans and Aspergillus niger. Yeast cells were incubated with the compounds for 24 or 48 hours whereas A. niger cells were incubated with the compounds for 16, 24, 48 or 72 hours respectively. Generally the presence of the N-methyl group decreases potency against yeast, whilst the opposite is true in A. niger. The compounds are not as effective at inhibiting cell growth against A. niger when compared to the yeast. Compound 41n was the most potent inhibitor giving IC90 values of 1.35 x 10-3 M (S. cerevisiae) and 1.55 x 10-3 M (C. albicans), whereas compound 39n was the most potent inhibitor of A.niger growth with an MIC value of 3.6 x 10-10 M. Selected piperidone dieneones were screened for cytotoxic properties against the A549 cancer cell line using the MTS and LDH assays. Compound 41n was found to be the most cytotoxic. Potency of benzene ring substitution was para>meta>ortho. Substituents of larger volume and lower electron withdrawing properties produce more potent compounds. The 3’-iodo substituted piperidones (39n and 41n) emerged as the most promising agents from the group of compounds in respect to their antifungal and cytotoxic potencies, although the compounds were not as effective as the reference drug miconazole.
Fact Sheet: Multiple stressors
Creators: name: The Nansen Legacy
Publisher: name: Zenodo
Year: 2024

description: This fact sheet is a deliverable of the project The Nansen Legacy, and it brings together core findings of the project. 

Scientific observations of many Nansen Legacy researchers form the background for this fact sheet. The following researchers have summarized the findings and provided the text on the fact sheet: K. Van Dinh (lead), K. Borgå, A.M.B. Gravelle, K. Hylland, J.E. Søreide (alphabetical order, apart from lead scientist).

All illustrations and the design of the fact sheet have been made by F.A. Cnossen.
МЕТОДОЛОГИЯ ОЦЕНКИ ЭФФЕКТИВНОСТИ ГОСУДАРСТВЕННОЙ ПРОГРАММЫ "ОКАЗАНИЕ СОДЕЙСТВИЯ ДОБРОВОЛЬНОМУ ПЕРЕСЕЛЕНИЮ В РЕСПУБЛИКУ МОРДОВИЯ СООТЕЧЕСТВЕННИКОВ, ПРОЖИВАЮЩИХ ЗА РУБЕЖОМ"
Creators: name: ФОФАНОВА КАТЕРИНА ВЛАДИСЛАВОВНА
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: СООТЕЧЕСТВЕННИК
МЕТОДОЛОГИЯ
ЭФФЕКТИВНОСТЬ
ПЕРЕСЕЛЕНЕЦ
ГОСПРОГРАММА
COMPATRIOT
METHODOLOGY
EFFICIENCY
MIGRANT
STATE PROGRAM

description: В статье рассматривается программно-целевой подход как один из механизмов государственного регулирования. Программно-целевой подход рассматривается на примере Государственной программы по оказанию содействия добровольному переселению в Российскую Федерацию соотечественников, проживающих за рубежом. Указывается, что цель программы поставлена и сформулирована достаточно конкретно, вместе с тем встает вопрос относительно методологии измерения эффективности и результативности Госпрограммы. Ставится вопрос о необходимости разработки методологических оснований комплексной оценки эффективности Государственной программы по оказанию содействия переселению в Республику Мордовия соотечественников, проживающих за рубежом. Показано, что применяемая система измерения эффективности Госпрограммы, строится на восприятии переселенца как ресурса для регионов, предметом оценки являются отдельные ключевые параметры Госпрограммы: возраст, образование, объемы финансирования. Объективные показатели отражают общие тенденции и механизмы отбора соотечественников, промежуточные результаты реализации Госпрограммы, соответствие поставленной цели в программе, а не реальную оценку эффективности Госпрограммы, участниками которой выступают переселенцы с реальными проблемами, жизненными практиками и судьбами. Имеющиеся данные не отражают проблемы, трудности адаптации в регионе, изменения качества жизни, социального самочувствия переселенцев. Сделан вывод, что выбор стратегии измерения эффективности Госпрограммы в целом зависит от того, какой подход применять в отношении переселенцев-соотечественников гуманитарный или ресурсный.
Introduction: "Be true to the earth"
Creators: name: Rigby, Kate
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200599 Literary Studies not elsewhere classified
subject: FOS: Languages and literature

description: This special issue of Colloquy is devoted to the proceedings of last year’s Colloquy conference, “Be true to the earth” (March 31-April 1, 2005), which was the inaugural conference of the recently founded Association for the Study of Literature and the Environment (Australia-New Zealand). As the founding President of that Association, I was extremely grateful to Dimitris Vardoulakis and the rest of the Colloquy editorial team for offering to host our first major international gathering, and I am honoured to have the opportunity to guest edit the wonderful issue of the journal that has resulted from it, ably assisted by Peter Coleman, who led the conference organisation, Samantha Capon and Barbara Ghattas.
Additional file 9 of Study and QTL mapping of reproductive and morphological traits implicated in the autofertility of faba bean
Creators: name: Aguilar-Benitez, David
name: Casimiro-Soriguer, Inés
name: Ferrandiz, Cristina
name: Torres, Ana M.
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9. Scanning Electron Microscope measures of the flower. a) Stigma length (STIGL), rupture length (RUPTL), stigma area (STIGAREA), ruptured area (RUPTAREA), papilla length (PAPL), papilla width (PAPW). b) papilla density (PAPD, number of papillas in 6 mm2). c and d) measure of stigma angle (STIGA). Bar: 200 µm.
Analysis of G-Quadruplex Formation in mRNA Transcripts of Phospholemman/FXYD1
Creators: name: Dhayan, Hansraj
Publisher: name: University of Hertfordshire
Year: 2014
Subjects: Guanine-rich(G-rich) sequences
Intramolecular/Intermolecular G-quadruplex
in-vitro G-quadruplex
RNA G-quadruplex
Phospholemman
FXYD1
Sodium Potassium pump (NKA)
gene regulation
alternative splicing
introns
exons
UTR regions
pre-mRNA
splice variant
FXYD1-009
Native polyacrylamide gel electrophoresis(PAGE)
Intrinsic fluorescence spectroscopy
Vienna RNA package 2.0
QGRS mapper
Quadbase
Multiple Sequence Alignment MAFFT
Conserved G-rich sequences
Comparative analysis

description: G-quadruplexes are higher-order nucleic acid structures formed by tetrads of guanine bases (G-tetrads) through non-canonical base interactions. Two G-tetrads are stabilised by a potassium-ion sandwiched between the tetrads. It has emerged from recent studies that G-quadruplexes occur widely throughout the human genome and have significant biological roles. In this study the FXYD1 pre-mRNA encoding the protein Phospholemman (PLM) is investigated. PLM is highly expressed in cardiomyocytes and forms a third subunit of the Na+/K+ pump (NKA). PLM is a major phosphorylation target and thus regulates NKA activity. FXYD1 pre-mRNA was investigated for its ability to form G-quadruplexes. By computational analysis, it was found that FXYD1 can fold into G-quadruplex and multiple sequence alignment of ortholog FXYD1 sequences indicated that G-quadruplex-forming potential is conserved in evolution, hinting at a potential regulatory mechanism of FXYD1 expression. Comparative analysis confirmed that FXYD1-009, a variant of FXYD1, is a product of alternative splicing of FXYD1’s pre-mRNA. G-quadruplex formation in human and bovine FXYD1-derived oligonucleotides was detected experimentally by non-denaturing poly acrylamide gel electrophoresis that showed an increased mobility rate of G-quadruplexes in contrast to controls. Further analysis by fluorescence emission spectroscopy confirmed G-quadruplex formation in the human and bovine FXYD1-oligonucleotides that was triggered by the presence of K+ ions. The results provided clear evidence of G-quadruplex formation in vitro and together with evolutionary conservation point to potential role in regulating expression of FXYD1 possibly through alternative splicing and thus regulate indirectly the activity of Na+/K+-ATPase. Further in-vivo works should address whether alternative splicing of FXYD1 to FXYD1-009 is associated with G-quadruplex formation.
Editorial and front matter: Colloquy, Issue 12, November 2006
Creators: name: Colloquy
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200599 Literary Studies not elsewhere classified
subject: FOS: Languages and literature

description: COLLOQUY: text theory critique Issue 12, November 2006
 Be true to the earth guest edited by Kate Rigby with Samantha Capon, Peter C. Coleman, Barbara Ghattas
-----Issue 12 of Colloquy: text theory critique publishes the proceedings of the conference Be true to the earth, which took place at Monash University on March 31-April 1, 2005 and which was co-organized by Colloquy. The collection of papers, edited by Samantha Capon, Peter Coleman, Barbara Ghattas and Kate Rigby, focuses on eco-criticism and eco-philosophy and contains articles on a wide range of topics, from Nietzsche to Patrick White, from Orwell to Judith Wright, from landscape and poetry to earth-based ethics. A number of people made possible the realization of this issue, first and foremost the referees who reviewed the articles and whom the editors want to thank.
Additional file 1: of Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair
Creators: name: Ye, Jing
name: Zha, Jie
name: Shi, Yuanfei
name: Li, Yin
name: Yuan, Delin
name: Chen, Qinwei
name: Lin, Fusheng
name: Fang, Zhihong
name: Yu, Yong
name: Dai, Yun
name: Xu, Bing
Publisher: name: figshare
Year: 2019
Subjects: subject: Biophysics
subject: Biochemistry
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Figure S1. The HDAC inhibitor chidamide and the Menin-MLL interaction inhibitor MI-3 display dose- and time-dependent effects on viability of MLL-r AML cells. Figure S2. The regimen combining chidamide and MI-3 is not effective in non-MLL-r AML cells. Figure S3. Co-treatment with chidamide and MI-3 induces robust apoptosis, ROS generation, and loss of mitochondrial membrane potential in MLL-r MV4-11 cells. Figure S4. The KEGG analysis of the RNAseq data reveals involvement of multiple cell cycle and DNA repair pathways in the interaction between chidamide and MI-3 in MLL-r AML cells. Figure S5. Genome-wide RNA sequencing identifies four genes that are differentially expressed in MOLM-13 cells treated with MI-3 vs. chidamide alone or in combination. Figure S6. Treatment with chidamide results in increased acetylation of histone H3 in both MLL-r and non-MLL-r AML cells. (DOCX 3896 kb)
Supplementary Material for: A Critical Evaluation of sst3 and sst5 Immunohistochemistry in Human Pituitary Adenomas
Creators: name: Körner, M.
name: Waser, B.
name: Christ, E.
name: Beck, J.
name: Reubi, J.C.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Background: Somatostatin receptor (sst) overexpression in neuroendocrine tumors allows sst-targeted tumor imaging and therapy with long-acting, cold, or radioactive somatostatin analogs. sst2 has been most important, owing to its wide overexpression and high affinity for somatostatin analogs, but other sst subtypes become of increasing clinical interest due to drug development. Immunohistochemistry is the preferred method to detect sst in resected tumor tissues. While it is established for sst2 using the antibody UMB-1, there is less experience for other sst subtypes. Methods: sst3 and sst5 immunohistochemistry using the antibodies UMB-5 and UMB-4 was evaluated in 60 pituitary adenomas and compared with in vitro sst autoradiography (ARG), the in vitro gold standard method to assess sst. Results: UMB-4 immunohistochemistry for sst5 yielded membranous staining of tumor cells. It correlated fairly well with ARG, results matching in 80% of tumors. UMB-5 immunohistochemistry for sst3 showed not only a membranous, but also cytoplasmic background staining. Agreement with ARG was limited. All tumors showed UMB-5 staining, while only 57% were positive by ARG. In comparison, UMB-1 staining levels showed a highly significant correlation with autoradiographic sst2 density levels (R2 = 0.797). Not only tumor cells, but also intratumoral blood vessels were immunohistochemically positive for sst2, 3, and 5. Conclusion: UMB-1 immunohistochemistry for sst2 is excellent. sst3 immunohistochemistry using UMB-5 is not yet optimal, with suspected limited specificity, and should be applied with caution. UMB-4 immunohistochemistry for sst5 appears to be equivalent to sst5-ARG and suitable for diagnostic applications.
РЕКРУТЧИНА КАК НАКАЗАНИЕ: СОЦИАЛЬНЫЙ КОНТРОЛЬ И ОХРАНА ПРАВОПОРЯДКА В ДОРЕФОРМЕННОЙ ДЕРЕВНЕ (ПО МАТЕРИАЛАМ АРДАТОВСКОГО УЕЗДА СИМБИРСКОЙ ГУБЕРНИИ)
Creators: name: БОРИСОВ БОРИС АЛЕКСАНДРОВИЧ
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: ДВОРЯНСТВО
РЕКРУТЧИНА
КРЕСТЬЯНСТВО
КРЕПОСТНИЧЕСТВО
ПРАВОНАРУШЕНИЕ
СОЦИАЛЬНЫЙ КОНТРОЛЬ
СЕМЬЯ
NOBILITY
CONSCRIPTION
PEASANTRY
SERFDOM
OFFENCE
SOCIAL CONTROL
FAMILY

description: В контексте исследования механизмов социального контроля и профилактики правонарушений в России имперского периода в статье анализируется рекрутчина, представляемая автором в качестве действенного способа воздействия на народные массы. На основании архивных материалов и опубликованных источников автором устанавливаются причины негативного отношения населения к выполнению воинской повинности, определяется влияние, оказываемое рекрутской повинностью на крестьянские хозяйства. Анализируя урон, наносимый военной обязанностью крестьянству, автор предлагает учитывать не только длительность срока службы, но и то, что основная масса демобилизовавшихся уже не возвращалась на свои прежние места жительства. В качестве основных видов правонарушений, за которые в рассматриваемый период могла последовать отправка в войска, выделяются бегство с постоянного места жительства, кража, хулиганство, членовредительство. На конкретных примерах из истории Ардатовского уезда Симбирской губернии автором показывается то, что помещиками в первой половине XIX столетия рекрутчина использовалась в качестве средства воздействия на неугодных крепостных.
A new 1,2-ethanedione benzofurane derivative from Tephrosia purpurea
Creators: name: Peng, Yan
name: Chen, Yinning
name: Gao, Chenghai
name: Yan, Tao
name: Cao, Wenhao
name: Huang, Riming
Publisher: name: Taylor & Francis
Year: 2014
Subjects: Science Policy
Biological Sciences
Chemistry
Earth and Environmental Sciences
Biochemistry

description: A new 1,2-ethanedione benzofurane derivative, purpdione (1), was isolated from Tephrosia purpurea, together with seven known flavonoids, purpurenone (2), pongamol (3), ovalitenin A (4), karanjin (5), lanceolatin B (6), tachrosin (7) and villosinol (8). The new structure was elucidated based on the analysis of its spectroscopic data. The structures of the known compounds were identified by comparing their spectroscopic data with those reported in the literature. The isolates exhibited marginal ability to inhibit the settlement of barnacle (Balanus reticulatus).
ФОРМИРОВАНИЕ МИЛИЦИИ НА ТЕРРИТОРИИ ТЕМНИКОВСКОГО УЕЗДА ТАМБОВСКОЙ ГУБЕРНИИ В 1917 ГОДУ
Creators: name: КИСТАНОВ СЕРГЕЙ ВАСИЛЬЕВИЧ
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: РЕВОЛЮЦИЯ
ВРЕМЕННОЕ ПРАВИТЕЛЬСТВО
ПОЛИЦИЯ
МИЛИЦИЯ
ЗЕМСКОЕ СОБРАНИЕ
ГОРОДСКАЯ ДУМА
КРИЗИС
REVOLUTION
PROVISIONAL GOVERNMENT
POLICE
PROVINCIAL ASSEMBLY
CITY COUNCIL
CRISIS

description: В статье рассматривается процесс формирования в 1917 г. милиции на территории Темниковского уезда Тамбовской губернии. После расформирования полиции, создание охранных структур должно было стать важным направлением в деятельности местных органов власти Временного правительства. Отмечаются основные вехи процесса становления милиции в уезде, проходившем на заседаниях уездных земских и городских властей. Рассматривается структура и основные обязанности создаваемой милиции на основании Постановления Временного правительства от 17 апреля 1917 г. Подробно анализируется финансирование органов милиции в период марта-сентября 1917 г., отмечаются источники финансирования, и рассматривается жалование сотрудников в соответствии с занимаемыми должностями. Отмечаются трудности, в процессе создания милиции в Темниковском уезде нехватка сотрудников и низкое жалование милиционеров. Анализируется дискуссия земских и городских органов власти по вопросу финансирования и нехватки средств на содержание милиции и констатируется, что, к сожалению, решение данных вопросов не вышло в реальную плоскость, а так и осталось лишь в виде резолюций Городской думы и Земского собрания Темниковского уезда. Данные проблемы, так и не решенные властями, станут одними из факторов, которые привели к смене политической власти в уезде.
The Relationship between Nutrition Knowledge and Performance Measures in British Collegiate American Football Athletes
Creators: name: Clemo, Matthew Philip
Publisher: name: University of Hertfordshire
Year: 2014
Subjects: American football
Nutrition
Euclid
Performance testing
Nutrition knowledge
Performance score

description: The purpose of this thesis was to ascertain whether or not a significant relationship exists between nutrition knowledge and athletic performance among British collegiate American football athletes. In order to quantify an athlete’s nutrition knowledge and overall performance ability, a nutrition knowledge questionnaire was developed and a new performance assessment tool (Euclid) was evaluated. The nutrition knowledge questionnaire was developed using validation and reliability procedures. From the initial thirty-four questions, nine were removed due to a lack of significance shown when testing for construct validity, and a further two were also removed following the results of tests for internal consistency. The remaining twenty-three questions formed the valid and reliable questionnaire that was utilised to quantify an athlete’s nutrition knowledge. Next, the Euclid model was evaluated as a way of quantifying overall athletic performance in American football in comparison with previously used methods in this area of research. The greatest support for the model’s applicability came from the observed significant relationships between Euclid scores and competitive experience among offensive and defensive starters (n = 6, r = 0.922, p = 0.026; n = 4, r = 0.999, p = 0.022). While significance was not consistently observed between the Euclid performance scores and other control methods, the results warranted further examination of the model. When the nutrition knowledge questionnaire and the Euclid model were used with a British collegiate American football population, results were found to suggest the existence of a relationship between some of the variables. The offensive athletes demonstrated a significant relationship between nutrition knowledge and performance scores (n = 16; r = -0.610, p = 0.012). However, as significance was not observed for the whole group, or for the defensive athletes, further research will be required to discover the true impact of nutrition knowledge on athletic performance in American football.
Tunable morphology and surface wettability of an amphiphilic azobenzene derivative and its melamine-induced self-assembly
Creators: name: Jiang, Hao
name: Hu, Wenlong
name: Li, Jingguo
name: Yang, Guang
name: Zou, Gang
name: Zhang, Qijin
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Biological Sciences
Chemistry
Earth and Environmental Sciences
Biotechnology
Physics
Biochemistry
Biophysics

description: Herein, a series of novel hydrogen-bonded complexes derived from 4-[[(dodecyloxy)benz-4-yl]azo]benzoic acid (DBA) and melamine are reported. The morphology and surface wettability of the resulting self-assembled supramolecular architectures can be easily modulated not only by varying the molar ratios of DBA and melamine, but also by external UV irradiation. Based on the results of atomic force microscope, X-ray diffractometer and contact angle measurements, orientation of the coassembled units with different molar ratios of DBA and melamine could be clearly confirmed. Moreover, the effect of photo-isomerisation of the azobenzene units on the wettability of the assemblies has been investigated in detail. As we know, the films derived from the cis-azobenzene derivative usually exhibit a more hydrophilic property than that from the trans-azobenzene derivative. However, the opposite results were obtained for the samples derived from the cis isomers of DBA–melamine (3:1) complexes or DBA. An explanation, based on the surfaces topography, has been proposed.
Nietzsche contra Lawrence: How to be True to the Earth
Creators: name: Garrard, Greg
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200599 Literary Studies not elsewhere classified
subject: FOS: Languages and literature
subject: Philosophy
subject: FOS: Philosophy, ethics and religion

description: Both Nietzsche and Lawrence have been identified as important forerunners and progenitors in the development of an ecocentric, “posthumanist” worldview. Nietzsche suggested, and Lawrence developed, the notion of an anti-mechanistic “gay science”. Both writers rejected the Christian denigration of nature, the Romantic notion of a “return to nature” and the instrumentalisation of nature by industrial rationality in favour of a conception of the good life founded in the body and an almost utopian “ascent to nature”. However, since the ascent to nature required an overcoming of existing humanity, both Nietzsche and Lawrence faced the task of articulating a conception of the Over-man – or post-human, as contemporary theory would put it – that is not merely a figure of authoritarian brutality. Deep ecologist Del Ivan Janik has claimed that Lawrence “saw man as part of an organic universe, living best by acknowledging its wonder and rejecting the temptation to force his will upon it. In this sense he stands at the beginning of the modern posthumanist tradition and of the literature of environmental consciousness.” Accurate as this assessment is, however, the struggle with questions of power, gender, sexuality and religion that early posthumanism involved has tended to be airbrushed out of the dark green reading of Lawrence. And Lawrence's personal spiritual and intellectual struggle was also a creative conflict with Nietzsche.
A mathematical model of aerobic methane oxidation coupled to denitrification
Creators: name: Modin, Oskar
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Inorganic Chemistry
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Aerobic methanotrophic bacteria use methane as their only source of energy and carbon. They release organic compounds that can serve as electron donors for co-existing denitrifiers. This interaction between methanotrophs and denitrifiers is known to contribute to nitrogen losses in natural environments and has also been exploited by researchers for denitrification of nitrate-contaminated wastewater. The purpose of this study was to develop a mathematical model describing aerobic methane oxidation coupled to denitrification in suspended-growth reactors. The model considered the activities of three microbial groups: aerobic methanotrophs, facultative methylotrophs, and facultative heterotrophs. The model was tested against data from the scientific literature and used to explore the effects of the oxygen mass transfer coefficient, the solids retention time, and the fraction methane in the feed gas on nitrate removal. The fraction of methane in the feed gas was found to be critical for the nitrate removal rate. A value of about 15% in air was optimal. A lower methane fraction led to excess oxygen, which was detrimental for denitrification. A higher fraction led to oxygen-limitation, which restricted the growth rate of methanotrophs in the reactor.
Can We Have a Kierkegaardian Self Without God?: Kierkegaard, Bernard Williams and Ground Projects
Creators: name: Dekany, Istvan Mark
Publisher: name: University of Hertfordshire
Year: 2014
Subjects: Kierkegaard
The Self
Bernard Williams
Ground Projects

description: This dissertation will explore Kierkegaard's notion of the self, primarily in his work The Sickness Unto Death. While Kierkegaard claims that it is impossible for an individual to become a full self without God, this paper will show that the necessary role that God plays in self-development can be fulfilled without references to God, allowing full self-development in a secular context. As such, focus will be placed on the need for objective values and unity of the self as described by Kierkegaard, while highlighting how an iteration of Bernard Williams's view of ground projects may fulfill the necessary role Kierkegaard ascribes to God.
ПРОЦЕССЫ ПЕРЕРАСПРЕДЕЛЕНИЯ ЗЕМЕЛЬНОЙ СОБСТВЕННОСТИ В СРЕДЕ ЧАСТНОГО ЗЕМЛЕВЛАДЕНИЯ СРЕДНЕГО ПОВОЛЖЬЯ ВО ВТОРОЙ ПОЛОВИНЕ XIX - НАЧАЛЕ XX ВЕКА
Creators: name: ФЕДОСЕЕВ РОМАН ВАСИЛЬЕВИЧ
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: ЧАСТНОЕ ЗЕМЛЕВЛАДЕНИЕ
СРЕДНЕЕ ПОВОЛЖЬЕ
ГУБЕРНИЯ
ПОМЕСТНОЕ ДВОРЯНСТВО
ПЕРЕРАСПРЕДЕЛЕНИЕ ЗЕМЕЛЬНОЙ СОБСТВЕННОСТИ
СТАТИСТИКА ЗЕМЛЕВЛАДЕНИЯ
ЗЕМЕЛЬНАЯ РЕФОРМА
СТРУКТУРА
PRIVATE LAND OWNERSHIP
MIDDLE VOLGA REGION
PROVINCE
LOCAL NOBILITY
REDISTRIBUTION OF LAND OWNERSHIP
STATISTICS OF LAND OWNERSHIP
LAND REFORM
STRUCTURE

description: Эпоха великих реформ Александра II, затронувших практически все сферы общественной жизни, включила в себя и назревшую земельную реформу, которая, помимо освобождения крестьян, имела еще один немаловажный аспект закрепление возможности приобретать и продавать земли представителям различных сословий, а не только дворянам. Данное обстоятельство вызвало небывалую активность на земельном рынке и вовлекло в категорию частных землевладельцев многие сословия, ранее не имевшие возможности участвовать в сделках по купле-продаже земель. На примере губерний Среднего Поволжья в статье изучаются вызванные описанными выше причинами процессы перераспределения земельной собственности в среде частного землевладения. На основе дореволюционной статистики убедительно показано, что основными продавцами на земельном рынке были дворяне, а покупателями крестьянство и купечество. Рассмотрены основные причины сложившейся в тот период ситуации, приводятся многочисленные цифровые данные, подтверждающие указанный ранее вывод. Кроме того, в статье показаны данные по отдельным губерниям Среднего Поволжья, демонстрирующие темпы сокращения дворянского землевладения и указывающие на то, что они имели разноскоростной характер.
Depois das antigas traduções da Bíblia
Creators: name: Vaz, Armindo Dos Santos
Publisher: name: Didaskalia
Year: 2014

description: As traduções modernas da Bíblia no Ocidente cruzam-se com a própria história ocidental: escreveram um nobre capítulo, ao oferecerem-lhe a base para a sua matriz cristã, para a democracia, liberdade e fraternidade humana. Fizeram cultura e literatura, enriqueceram a tradição da pintura, com miniaturas e iluminuras de rara beleza. Foram determinantes para a Bíblia chegar aos sedentos da sua mensagem inspiradora e para esta sobreviver no presente de cada povo. Por elas, a Bíblia continuou a falar ao longo de mais de um milénio. Prescindindo de outros dados a ter presentes no difícil ato de a traduzir (critérios literários, hermenêuticos, teológicos, litúrgicos…), fazemos uma abordagem histórica à tradução para as línguas mais faladas do Ocidente (francês, italiano, alemão, inglês, espanhol, português), acompanhando as circunstâncias em que cada uma surgiu e influenciou a religiosidade dos povos que a faziam e acolhiam. Um fenómeno com que esbarrou essa aventura foi o das proibições de a traduzir e ler. Por um lado, aparentemente incompreensível, revela, por outro, o sumo cuidado por preservar inalterado o seu precioso conteúdo, tentando evitar que fosse adulterado. Se algumas proibições se revestiram de dramatismo, outras ficaram tingidas de perseguição e de sangue, o que denuncia bem o ardente desejo de a dar a ler.
description: Didaskalia, v. 44 n. 1 (2014): Bíblia, tradução e leitura
A Green Flaw in the Crystal Glass: Patrick White’s Riders in the Chariot
Creators: name: Ralph, Iris
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200502 Australian Literature (excl. Aboriginal and Torres Strait Islander Literature)
subject: FOS: Languages and literature

description: As he himself averred more than once and as the critical reception recognises, Australian writer Patrick White identifies with a literary tradition that is metaphysical, romantic, and theosophical in its avenues of inquiry and its impulses. A 1969 essay by White titled “In the Making,” opens with this statement: “Religion. Yes, that’s behind all my books. What I am interested in is the relationship between the blundering human being and God.” A 1970 correspondence by White houses this comment: “I believe most people have a religious factor, but are afraid that by admitting it they will forfeit their right to be considered intellectuals.”
A leitura canónica do texto bíblico à luz de seu medium hermeneuticum e de seu escopo soteriológico
Creators: name: Silva, Luís Henrique Eloy E
Publisher: name: Didaskalia
Year: 2014

description: O artigo visa discutir a questão da chamada “leitura canónica” e seu papel na compreensão teológica do texto bíblico. Após a contextualização da questão, será abordada a problemática da expressão “leitura canónica” e seus correlatos mais conhecidos como “abordagem canónica”, “criticismo canónico” e “exegese canónica”. Em seguida, analisar-se-á o conceito cânon em suas dimensões exclusiva, inclusiva e intrínseca, para finalmente, pôr-se a questão presente no título do artigo.
description: Didaskalia, v. 44 n. 1 (2014): Bíblia, tradução e leitura
A new phenyl glycoside from the aerial parts of Equisetum hyemale
Creators: name: Jin, Mei
name: Zhang, Changhao
name: Zheng, Tie
name: Yao, Dalei
name: Shen, Le
name: Luo, Jie
name: Jiang, Zhe
name: Ma, Juan
name: Jin, Xue-Jun
name: Cui, Jiongmo
name: Lee, Jung Joon
name: Li, Gao
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Microbiology
subject: Biochemistry

description: A new phenyl glycoside, 2-(sophorosyl)-1-(4-hydroxyphenyl)ethanone (9), was isolated from the ethanolic extract of the aerial parts of Equisetum hyemale L., together with eight known compounds (1–8). The structures of these compounds were elucidated using a combination of spectroscopic analyses and chemical method. Of these nine compounds, 4 and 7 showed hepatoprotective effects towards tacrine-induced cytotoxicity in Hep 3B cells with EC50 values of 42.7 ± 1.5 and 132.6 ± 2.8 μM, respectively.
ИНСТИТУТ ОПРОСА ГРАЖДАН: ОТ РЕКОМЕНДАТЕЛЬНОГО РЕЗУЛЬТАТА К ИМПЕРАТИВНОЙ ФОРМЕ
Creators: name: КУРАКИНА СВЕТЛАНА ИВАНОВНА
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: ДЕМОКРАТИЯ
НЕПОСРЕДСТВЕННЫЕ ФОРМЫ ДЕМОКРАТИИ
ОПРОС
МЕСТНЫЙ РЕФЕРЕНДУМ
DEMOCRACY
DIRECT FORMS OF DEMOCRACY
POLL
LOCAL REFERENDUM

description: Взятый Российской Федерацией курс на закрепление и развитие демократических ценностей подталкивает нас к исследованию и обсуждению механизмов совершенствования институтов народной демократии. Одним из дееспособных способов выявления общественного мнения является опрос граждан. Несмотря на то, что проблемам изучения правовой природы института опроса граждан посвящено достаточное количество работ, в свете последних политических событий в стране, связанных с гражданским противостоянием в городе Екатеринбурге, возрастает актуальность исследования форм определения общественного мнения населения. В статье анализируется современное состояние федерального и регионального законодательства, посвященного институту опроса граждан. Автором проведен сравнительный разбор регионального и муниципального правотворчества касающегося организации и проведения опроса в субъектах Российской Федерации, сделана рекомендация, с учетом которой могло бы совершенствоваться законодательство Российской Федерации и ее субъектов.
“Keep Close to the Earth!” The Schism between the Worker and Nature in Katharine Susannah Prichard’s Novels
Creators: name: Barker, Karen
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200502 Australian Literature (excl. Aboriginal and Torres Strait Islander Literature)
subject: FOS: Languages and literature

description: “It’s good to keep close to the earth,” Sophie Roumanoff tells her husband Potch in Katharine Susannah Prichard’s Black Opal (1921; Sydney: Caslon House, 1946). Prichard’s own reasons for wanting to keep close to the earth were ostensibly Communist and Marxist. In the year prior to the publication of Black Opal she had been a foundation member of the Com- munist Party of Australia, and shortly afterwards established a Labor Study Circle in Perth where she lectured a mainly working class audience on Marxist notions of historical materialism and industrial organisation. Marxism for Prichard was closely connected to the human relationship with nature, or “the earth.” But this was neither early recognition of the Marxist concern with ecological sustainability nor the sort of environmentalism or eco-Marxism which attributes environmental disruption to the capitalist accumulation of wealth. Prichard’s primary concern was not to protect the environment against the ravages of capitalist exploitation but to improve human welfare. Although her novels reveal a clear awareness of the environmental impact of large scale industrialisation and mechanisation, her first reference point is always human well-being. She considered stronger links to nature to be a fundamental prerequisite to improved social conditions and an essential component of her industrial reform agenda. Only under a socialist system, she believed, would Australia’s vast natural resources be mobilised in support of a broader “human welfare,” rather than the financial profits of a few.
ПОНЯТИЕ ДОБРОПОРЯДОЧНОСТИ: ОТ МОРАЛЬНО-НРАВСТВЕННОГО КАЧЕСТВА К ПРИНЦИПУ ПРАВА
Creators: name: МХИТАРЯН ЛЮДМИЛА ЮРЬЕВНА
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: ДОБРОПОРЯДОЧНОСТЬ
ДОБРОСОВЕСТНОСТЬ
ПРИНЦИПЫ ПРАВА
INTEGRITY
CONSCIENTIOUSNESS
PRINCIPLES OF LAW

description: В статье анализируются различные научные подходы к определению категории «добропорядочность». Отмечается, что данный термин широко применяется в философии, экономике, этике, ряде других наук. Добропорядочность понятие многозначное, имеет различные значения в зависимости от контекста, в котором оно употребляется. В юриспруденции данный термин также широко распространен. Однако нередко добропорядочность используют как синоним другого термина добросовестность. Тем не менее, понятия добросовестности и добропорядочности не идентичны. Это выражается, в том числе, в закреплении добропорядочности в федеральных законах и других нормативных актах, в том числе посвященных деятельности государственных гражданских служащих. При этом добропорядочность следует рассматривать именно как принцип права. На сегодняшний день он не обладает статусом общеправового принципа, коим обладают принципы законности, справедливости, гуманизма и прочих принципов. Автор приходит к выводу о необходимости возведения добропорядочности в категорию общеправового принципа права. Также следует конкретизировать тот образ поведения, который понимается законодателем как добропорядочный.
Salt-lakes and Swamps: Michael Meehan's Australian Environments
Creators: name: Pritchard, Greg
Publisher: name: Monash University
Year: 2017
Subjects: subject: 200502 Australian Literature (excl. Aboriginal and Torres Strait Islander Literature)
subject: FOS: Languages and literature

description: The representation of landscape has been an important part of Australian literature, and the imagined Australian character has partly been constructed relative to interactions with the natural world. Often, the land has been framed against an idealised European landscape, and depicted in anthropomorphised terms, as being harsh and unforgiving. In keeping with the idea of landscape as important, Michael Meehan's first two novels, The Salt of Broken Tears and Stormy Weather, have rural Victoria as a setting and character.
Metastatic spinal cord compression as the first sign of malignancy
Creators: name: Wänman, Johan
name: Grabowski, Pawel
name: Nyström, Helena
name: Gustafsson, Patrik
name: Bergh, Anders
name: Widmark, Anders
name: Crnalic, Sead
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer

description: Background and purpose — Metastatic spinal cord compression (MSCC) as the initial manifestation of malignancy (IMM) limits the time for diagnostic workup; most often, treatment is required before the final primary tumor diagnosis. We evaluated neurological outcome, complications, survival, and the manner of diagnosing the primary tumor in patients who were operated for MSCC as the IMM. Patients and methods — Records of 69 consecutive patients (51 men) who underwent surgery for MSCC as the IMM were reviewed. The patients had no history of cancer when they presented with pain (n = 2) and/or neurological symptoms (n = 67). Results — The primary tumor was identified in 59 patients. In 10 patients, no specific diagnosis could be established, and they were therefore defined as having cancer of unknown primary tumor (CUP). At the end of the study, 16 patients were still alive (median follow-up 2.5 years). The overall survival time was 20 months. Patients with CUP had the shortest survival (3.5 months) whereas patients with prostate cancer (6 years) and myeloma (5 years) had the longest survival. 20 of the 39 patients who were non-ambulatory preoperatively regained walking ability, and 29 of the 30 ambulatory patients preoperatively retained their walking ability 1 month postoperatively. 15 of the 69 patients suffered from a total of 20 complications within 1 month postoperatively. Interpretation — Postoperative survival with MSCC as the IMM depends on the type of primary tumor. Surgery in these patients maintains and improves ambulatory function.
Convenient approach to synthesize tertiary α-hydroxy cyclic phosphonates catalyzed by potassium carbonate under solvent-free conditions
Creators: name: Wang, Chubei
name: Zhou, Jianwei
name: Liu, Jianfeng
name: Chu, Liangliang
name: He, Hongwu
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Science Policy
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: GRAPHICAL ABSTRACT
Assembly of two new polyoxometalate-templated supramolecular compounds by utilizing flexible 1,4-bis(pyrazol-1-ylmethyl)benzene ligand
Creators: name: Zhao, Chunyan
name: Ma, Huiyuan
name: Pang, Haijun
name: Li, Shaobin
name: Yu, Yan
name: Yu, Tingting
name: Zhang, Zhuanfang
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: Two new polyoxometalate-templated supramolecular compounds, [CuI4(bpmb)4][PMoVI11MoVO40] (1) and [CuI4(bpmb)4SiW12O40] (2) (bpmb = 1,4-bis(pyrazol-1-ylmethyl)benzene), have been synthesized under hydrothermal conditions and characterized by routine methods. Structural analysis shows that in 1, there exist crown-like [CuI4(bpmb)4] coordination macrocycles, and the Keggin polyanions [PMo VI11MoVO40]4− (abbr. as PMo12), which direct the crown-like macrocycle to form a 3-D supramolecular framework. In 2, there exist unusual meso-helix chains, and these chains are mutually interlaced in a wave–trough pattern, but without intersection resulting in a multi-cavity layer, in which the [SiW12O40]4− (abbr. as SiW12) clusters as guest molecules occupy the cavities of the layers. The distinct structural features of the two compounds suggest that Keggin polyanions should play a significant role in the process of assembly. Electrocatalytic properties of 1 and 2 were investigated.
Assembly of two new polyoxometalate-templated supramolecular compounds by utilizing flexible 1,4-bis(pyrazol-1-ylmethyl)benzene ligand
Creators: name: Zhao, Chunyan
name: Ma, Huiyuan
name: Pang, Haijun
name: Li, Shaobin
name: Yu, Yan
name: Yu, Tingting
name: Zhang, Zhuanfang
Publisher: name: Taylor & Francis
Year: 2014
Subjects: subject: Biological Sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry

description: Two new POM-templated supramolecular compounds, [CuI4(bpmb)4][PMoVI11MoVO40] (1) and [CuI4(bpmb)4SiW12O40] (2) (bpmb = 1,4-bis(pyrazol-1-ylmethyl)benzene), have been synthesized under hydrothermal conditions and characterized by routine methods. Structural analysis shows that in 1 there exist crown-like [CuI4(bpmb)4] coordination macrocycles, and the Keggin polyanions [PMo VI11MoVO40]4- (abbr. as PMo12), which direct the crown-like macrocycle to form a 3D supramolecular framework. In 2 there exist unusual meso-helix chains, and these chains are mutually interlaced in a wave-trough pattern but without intersection resulting in a multi-cavity layer, in which the [SiW12O40]4- (abbr. as SiW12) clusters as guest molecules occupy the cavities of the layers. The distinct structural features of the two compounds suggest that Keggin anions should play a significant role in the process of assembly. Electrocatalytic properties of 1 and 2 were investigated.
МАЛОЗНАЧИТЕЛЬНОСТЬ КАК ОБСТОЯТЕЛЬСТВО, ИСКЛЮЧАЮЩЕЕ АДМИНИСТРАТИВНУЮ ОТВЕТСТВЕННОСТЬ: КРИТЕРИИ ПРИМЕНЕНИЯ
Creators: name: ПАЛЬЧИКОВА МАРИЯ ВАЛЕРЬЕВНА
Publisher: name: Гуманитарные и политико-правовые исследования
Year: 2019
Subjects: ПРАВОНАРУШЕНИЕ
АДМИНИСТРАТИВНАЯ ОТВЕТСТВЕННОСТЬ
МАЛОЗНАЧИТЕЛЬНОСТЬ
ПОЗИЦИИ ВЫСШИХ СУДОВ
КРИТЕРИИ МАЛОЗНАЧИТЕЛЬНОСТИ
OFFENSE
ADMINISTRATIVE RESPONSIBILITY
INSIGNIFICANCE
POSITIONS OF HIGHER COURTS
CRITERIA OF INSIGNIFICANCE

description: В статье рассматриваются вопросы применения малозначительности как основания освобождения от административной ответственности. В настоящий период времени сложилась противоречивая практика применения указанного основания, которая осложняется разными подходами судов общей юрисдикции и арбитражных судов РФ. На основании судебных решений высших судов в статье рассматриваются критерии малозначительности и дана попытка выделить универсальные правила применения данных признаков. В то же время автор показывает, что сформулировать абсолютно определенные критерии малозначительного правонарушения не представляется возможным, хотя эти попытки были предприняты в различных законопроектах. Анализ текстов законопроектов позволяет сформулировать общие признаки, на которые обращает внимание законодатель, дать им развернутую характеристику и соотнести с судебной практикой. В статье приведена единичная позиция Европейского суда по правам человека, в которой отражен концептуальный подход к пониманию универсальности правил право применения и баланса приоритетов государственного принуждения и свобод человека. В результате анализа судебной практики, позиций высших судов РФ и ЕСПЧ в статье сделан вывод о возможности выделения определенных критериев малозначительности для дальнейшего совершенствования практики применения и законодательной дефиниции.
Re-defining an Open Future, The Child's right to an Open Future revisited from a Virtue-Ethics perspective
Creators: name: Murdoch, Jenny
Publisher: name: University of Hertfordshire
Year: 2014
Subjects: Open future
autonomy
self-determination
character
virtue
'character education'
'children's rights'
'development needs'
'moral motivation'
'virtue ethics'
dispositions
identity

description: The over-riding goal of my thesis is to supplement Joel Feinberg’s (1980) argument for The Childs Right to an Open Future with ideas from Virtue Ethics, in order to gain a more comprehensive and satisfying account of the kind of autonomous ethical understanding that we ought to nurture in children. According to The Stanford Encyclopedia of Philosophy, ‘Put most simply, to be autonomous is to be one’s own person, to be directed by considerations, desires, conditions, and characteristics that are not simply imposed externally upon one, but are part of what can somehow be considered one’s authentic self. Autonomy in this sense seems an irrefutable value ...’ Feinberg’s open future is defined by the ‘right’ of self-determination and by the ‘good’ of self-fulfilment. In Part One, I consider Feinberg’s argument for the child’s right to an open future, which attempts to show from within a rights-based deontological framework, that children have rights to not have their future autonomy violated prior to reaching adulthood. This section includes my examination of major objections to Feinberg’s argument as well as discussion of supporting argument and my own analysis of the shortcomings of Feinberg’s argument. I conclude that, although I support the principle that the child’s autonomy ought to be preserved, Feinberg’s argument lacks attention to any kind of ethical grounding for self-determination. This leaves Feinberg’s argument vulnerable to the kinds of criticisms that connect an open future with selfish egoism and moral relativism. In Part Two, I attempt to supplement Feinberg’s rights-based deontological argument by demonstrating the ethical value of autonomy. I hope to extend, or redefine, the open future by focusing on an aspect of self-determination that Feinberg largely ignores – the capacity for self-determination. On my extended account of the open future, the capacity for self-determination is nurtured by helping children to develop the kinds of cognitive skills that will enable them to reason well about how to live and, consequently, how to act - but which must be underpinned by virtuous dispositions if we want the child’s choices to be ethically motivated, not just self-interested or arbitrary.