cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
In situ formation of SgrA* stars via disk fragmentation: parent cloud properties and thermodynamics
Creators: name: Mapelli, M.
name: Hayfield, T.
name: Mayer, L.
name: Wadsley, J.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The formation of the massive young stars surrounding SgrA* is still an open question. In this paper, we simulate the infall of a turbulent molecular cloud towards the Galactic Center (GC). We adopt two different cloud masses (4.3x10^4 and 1.3x10^5 solar masses). We run five simulations: the gas is assumed to be isothermal in four runs, whereas radiative cooling is included in the fifth run. In all the simulations, the molecular cloud is tidally disrupted, spirals towards the GC, and forms a small, dense and eccentric disk around SgrA*. With high resolution simulations, we follow the fragmentation of the gaseous disk. Star candidates form in a ring at ~0.1-0.4 pc from the super-massive black hole (SMBH) and have moderately eccentric orbits (~0.2-0.4), in good agreement with the observations. The mass function of star candidates is top-heavy only if the local gas temperature is high (>~100 K) during the star formation and if the parent cloud is sufficiently massive (>~10^5 solar masses). Thus, this study indicates that the infall of a massive molecular cloud is a viable scenario for the formation of massive stars around SgrA*, provided that the gas temperature is kept sufficiently high (>~100 K).
description: 16 pages, 16 figures, accepted for publication in ApJ
Agathe Reingruber, Die Argissa-Magula II. Das frühe und beginnende mittlere Neolithikum im Lichte transägäischer Beziehungen
Creators: name: Alram-Stern, Eva
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2020

description: Rezension zu: Agathe Reingruber, Die Argissa-Magula II. Das frühe und beginnende mittlere Neolithikum im Lichte transägäischer Beziehungen. Beiträge zur Ur- und Frühgeschichtlichen Archäologie des Mittelmeer-Kulturraumes Band 35. Verlag Dr. Rudolf Habelt, Bonn 2008. ISBN 978-3-7749-3495-5. 702 Seiten mit zahlreichen Abbildungen und 51 Tafeln
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 88 2010(2013)
title: Rekrutierungsquote des ärztlichen Personals aus der eigenen Studierendenschaft an der Uniklinik Köln
Creators: name: Karay, Yassin
name: Stosch, Christoph
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Immer wieder wird beschrieben, dass die Wertigkeit der Medizinischen Ausbildung in der Trias Lehre, Forschung und Krankenversorgung zu gering sei, da für die Motivation des Mitarbeiters (Forschungserfolge führen zu persönlichem Erfolg) oder der Abteilungen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Die Wirtschafts- und Finanzkrise mit Blick auf Marx und Keynes – Teil I
Creators: name: Buchholz, Günter
name: Voß, Stefan
name: Müller, Alfred
name: Jundt, Irina
Publisher: name: Hochschule Hannover
Year: 2011
Subjects: subject: 330 Wirtschaft

description: Enthält: Günter Buchholz: Einleitung - Die Krise ist die Kritik Stefan Voß: Kann die Hypothese der finanziellen Instabilität von Minsky die aktuelle Finanzkrise 2007/09 erklären? Alfred Müller: Kann die Wirtschafts- und Finanzkrise mit der Marxschen Theorie erklärt werden? Irina Jundt: Neue Finanzprodukte und Finanzmärkte
description: Arbeitspapier / Hochschule Hannover, Fakultät IV; 02/2011
Oncogenic dependency on STAT3 serine phosphorylation in Kras mutant lung cancer and cachexia
Creators: name: SULTAN MOHAMMED A ALHAYYANI
Publisher: name: Monash University
Year: 2019
Subjects: subject: Cancer
subject: Immunology
subject: FOS: Clinical medicine

description: Lung adenocarcinoma (LAC) is the most common (~40%) form of lung cancer, LAC is strongly associated with chronic lung inflammation triggered by cigarette smoking, and one of the most established disease-associated consequences of the genotoxic effects of cigarette-derived carcinogens is activating mutations in the Kras proto-oncogene. STAT3 has been shown to promote tumourigenesis. Therefore, we hypothesise that serine phosphorylation of STAT3 is a key event in the molecular pathogenesis of Kras-induced LAC. We discovered that STAT3 serine phosphorylation is required for both nuclear and mitochondrial function of STAT3 in Kras-induced LAC.
Julia Andrási, The Berthier-Delagarde Collection of Crimean Jewellery in the British Museum and Related Material
Creators: name: Heinrich-Tamáska, Orsolya
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2020

description: Rezension zu: Julia Andrási, The Berthier-Delagarde Collection of Crimean Jewellery in the British Museum and Related Material. With constributions by Aleksander Aibabin. The British Museum Company, London 2008. ISSN 1747-36-40; ISBN 978-086159-166-4. 173 Seiten mit zahlreichen Abbildungen
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 88 2010(2013)
TESTICULAR NEOPLASIA: FUNCTIONAL POLARIZATION OF MACROPHAGES AND DENDRITIC CELLS
Creators: name: DANA PUESCHL
Publisher: name: Monash University
Year: 2019
Subjects: subject: 111201 Cancer Cell Biology
subject: FOS: Clinical medicine

description: Testicular germ cell tumours (TGCTs) are most frequently associated with immune cell infiltrations that include macrophages and DCs. Macrophages and DCs can be involved in tumour progression and tumour destruction. Thus, a characterisation of macrophages and DC subsets that are associated with pathological alterations such as testicular neoplasia was conducted. Additionally, we investigated how tumour cells modulate immune cell responses. In conclusion, it is important to understand how immune cells, which serve an immune-protective role in the healthy testis, may contribute to the emergence or progression of TGCTs using strategies that reflect their diversity and functional flexibility.
§ 4 Keine Pflicht zur förmlichen Anhörung kreisangehöriger Gemeinden vor Festlegung des Kreisumlagesatzes
Creators: name: Reich, Daniel
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2020

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 13 (2019): Geprägte Freiheit 2019/20
title: Einfluss eines strukturierten Feedbacks auf Inhalt, Struktur und Qualität der Hauptvorlesung Chirurgie
Creators: name: Sterz, Jasmina
name: Höfer, Sebastian
name: Janko, Maren
name: Bender, Bernd
name: Britz, Vanessa
name: Marzi, Ingo
name: Rüsseler, Miriam
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Obwohl in der aktuellen Fassung der Approbationsordnung der Fokus immer mehr auf die Vermittlung praktischer Fertigkeiten gelegt wird, bleiben Vorlesungen immer noch die wichtigste Methode zur Vermittlungen theoretischer Inhalte.
    An unserer Fakultät berichten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Ärzte brauchen Führungskompetenz: Empathisches Konfliktmanagement und aktive Problemlösung als Führungskompetenzen in der ärztlichen Weiterbildung
Creators: name: Saravo, Barbara
name: Netzel, Janine
name: Schmidt-Huber, Marion
name: Fischer, Martin R.
name: Kiesewetter, Jan
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Assistenzärzte übernehmen von Beginn ihrer Weiterbildung an informelle Führungsverantwortung in zumeist interprofessionell zusammengestellten Teams, auf die sich viele nicht hinreichend vorbereitet fühlen [ref:3], [ref:2]. Trotz [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Quasi-elastic Neutrino Scattering - an Overview
Creators: name: Sobczyk, Jan T.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A non-technical overview of charge current quasi-elastic neutrino interaction is presented. Many body computations of multinucleon ejection which is proposed to explain recent large axial mass measurements are discussed. A few comments on recent experimental results reported at NuInt11 workshop are included.
description: 6 pages, no figures. A talk given at the NuInt11 Workshop, Dehradun, March 7-11, 2011
Uncovering the Protumourigenic Role of the ADAM17 Protease in Lung Cancer
Creators: name: MOHAMED IBRAHIM MOHAMED AHMED SAAD
Publisher: name: Monash University
Year: 2019
Subjects: subject: Cancer
subject: 60111 Signal Transduction
subject: FOS: Biological sciences
subject: 111201 Cancer Cell Biology
subject: FOS: Clinical medicine
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
subject: Molecular Biology

description: Lung adenocarcinoma is the most common form of lung cancer, the leading cause of cancer death worldwide. Mutations in the KRAS gene are the most studied causes of lung adenocarcinoma. However, the development of specific drugs inhibiting KRAS has proven challenging, and there is now a pressing need to identify new ways to inhibit KRAS. Using a series of preclinical KRAS mutant animal models, we found that the specific genetic and therapeutic inhibition of the protease ADAM17 suppressed tumour burden significantly. Our findings pave the way for the development of new drugs that can be used to treat lung adenocarcinoma.
Accurate parameters of 93 solar-type Kepler targets
Creators: name: Bruntt, H.
name: Basu, S.
name: Smalley, B.
name: Chaplin, W. J.
name: Verner, G. A.
name: Bedding, T. R.
name: Catala, C.
name: Gazzano, J. -C.
name: Molenda-Zakowicz, J.
name: Thygesen, A. O.
name: Uytterhoeven, K.
name: Hekker, S.
name: Huber, D.
name: Karoff, C.
name: Mathur, S.
name: Mosser, B.
name: Appourchaux, T.
name: Campante, T. L.
name: Elsworth, Y.
name: Garcia, R. A.
name: Handberg, R.
name: Metcalfe, T. S.
name: Quirion, P. -O.
name: Regulo, C.
name: Roxburgh, I. W.
name: Stello, D.
name: Christensen-Dalsgaard, J.
name: Kawaler, S. D.
name: Kjeldsen, H.
name: Morris, R. L.
name: Quintana, E. V.
name: Sanderfer, D. T.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a detailed spectroscopic study of 93 solar-type stars that are targets of the NASA/Kepler mission and provide detailed chemical composition of each target. We find that the overall metallicity is well-represented by Fe lines. Relative abundances of light elements (CNO) and alpha-elements are generally higher for low-metallicity stars. Our spectroscopic analysis benefits from the accurately measured surface gravity from the asteroseismic analysis of the Kepler light curves. The log g parameter is known to better than 0.03 dex and is held fixed in the analysis. We compare our Teff determination with a recent colour calibration of V-K (TYCHO V magnitude minus 2MASS Ks magnitude) and find very good agreement and a scatter of only 80 K, showing that for other nearby Kepler targets this index can be used. The asteroseismic log g values agree very well with the classical determination using Fe1-Fe2 balance, although we find a small systematic offset of 0.08 dex (asteroseismic log g values are lower). The abundance patterns of metals, alpha elements, and the light elements (CNO) show that a simple scaling by [Fe/H] is adequate to represent the metallicity of the stars, except for the stars with metallicity below -0.3, where alpha-enhancement becomes important. However, this is only important for a very small fraction of the Kepler sample. We therefore recommend that a simple scaling with [Fe/H] be employed in the asteroseismic analyses of large ensembles of solar-type stars.
description: MNRAS, in press, 12 pages
§ 13 Anspruch auf Barzahlung?
Creators: name: Kube, Hanno
Publisher: name: Heidelberger Beiträge zum Finanz- und Steuerrecht
Year: 2020

description: Heidelberger Beiträge zum Finanz- und Steuerrecht, Bd. 13 (2019): Geprägte Freiheit 2019/20
title: Nationales, longitudinales Mustercurriculum Kommunikation für die Medizin – Die Entwicklung der Longkomm-Toolbox
Creators: name: Kröll, Katrin
name: Ringel, Nadja
name: Weiss, Carmen
name: Mutschler, Anna
name: Brass, Konstantin
name: Kurtz, Winfried
name: Fellmer-Drüg, Erika
name: Gornostayeva, Maryna
name: Jünger, Jana
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Durch die erste Verordnung zur Änderung der Approbationsordnung für Ärzte im Mai 2012 wurde die Lehre und Prüfung kommunikativer Kompetenzen fest im Medizinstudium verankert. Dies eröffnete die Möglichkeit, kommunikative Kompetenzen von Studienbeginn[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Investigation into Ligand-Dependent Hedgehog Signalling in Development and Cancer
Creators: name: CATHERINE ROBERTA COCHRANE
Publisher: name: Monash University
Year: 2019
Subjects: subject: 111201 Cancer Cell Biology
subject: FOS: Clinical medicine
subject: Developmental Biology

description: The Hedgehog (Hh) signalling pathway plays critical roles in both developmental processes and cancer. However, the mechanisms known to regulate Hh signalling in cancer are not well understood. Investigating Hh signalling in models of development and cancer revealed a novel interaction between the cancer-related genes, p53 and Rb, and the cell-surface structure required for Hh signalling, primary cilia. Targeting this association with Hh-inhibitor drugs led to increased survival and tumour shrinkage in mouse models of the paediatric bone cancer, osteosarcoma. These findings propose p53 and Rb mutations, and primary cilia frequency as predictive biomarkers for Hh-inhibitor therapy in cancer.
title: Kommunikative Fertigkeiten mit E-Learning?
Creators: name: Martin, Olaf
name: Fink, Astrid
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: In der Ausbildung der Humanmedizin spielen kommunikative Fertigkeiten eine immer größere Rolle. Um Fertigkeiten auszubilden, muss zuvor das Tal der Wissensvermittlung durchschritten werden. Dieses kostet häufig Zeit, die im Lehrbetrieb nicht immer vorhanden[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Investigation of STAT3 Serine Phosphorylation in Gastric Tumourigenesis
Creators: name: JESSE JAY BALIC
Publisher: name: Monash University
Year: 2018
Subjects: subject: 111201 Cancer Cell Biology
subject: FOS: Clinical medicine
subject: Biochemistry
subject: Molecular Biology

description: Stomach cancer is a common worldwide health burden. It is aggressive and often diagnosed at a late stage. Currently, no blood test can detect this cancer and no curative treatment options are available. This thesis examined the role of a cancer causing protein called STAT3. It was discovered that this protein requires a special modification for its capacity to promote stomach inflammation and tumour growth. This study importantly defines a brand new therapeutic opportunity for the development of drugs that can target this modification, in the hopes to finally finding a cure for this lethal disease.
title: Fächerübergreifendes longitudinales Curriculum „Kommunikative und Soziale Kompetenzen“ an der Medizinischen Fakultät Carl Gustav Carus Dresden – Ergebnisse der IST-Stand-Erhebung
Creators: name: Lippmann, Maike
name: Zimmermann, Anja
name: Georgi, Bergitha
name: Hübner, Angela
name: Ohlenbusch-Harke, Theda
name: Sommer, Michael
name: Urban, Carolin
name: Weidner, Kerstin
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Im Rahmen eines fakultätsintern geförderten Projekts (MeDDrive-Lehre) wurde an der Medizinischen Fakultät in Dresden die aktuelle Lehrsituation hinsichtlich sozialer und kommunikativer Kompetenzen systematisch erfasst (IST-Stand-Erhebung). Darauf aufbauend[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Bedarf kommunikativer Lehrinhalte in der Zahnmedizin „ Ergebnisse einer Umfrage unter Studierenden
Creators: name: Krause, Felix
name: Schmalz, Gerhard
name: Haak, Rainer
name: Rockenbauch, Katrin
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Das Studium der Zahnmedizin zeichnet sich durch einen hohen Praktikumsanteil aus, so dass im klinischen Studienabschnitt bereits viele Kontakte mit Patienten stattfinden. Während in der Humanmedizin der Gegenstandskatalog Kommunikationsthemen beinhaltet, sieht die[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Emergence and Margins in Head and Neck Cancer: A new understanding
Creators: name: ELIZABETH ANNE SIGSTON
Publisher: name: Monash University
Year: 2019
Subjects: subject: Cancer
subject: 110323 Surgery
subject: FOS: Clinical medicine
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110504 Oral and Maxillofacial Surgery
subject: 110505 Oral Medicine and Pathology
subject: 60114 Systems Biology
subject: FOS: Biological sciences

description: Cancer has been widely accepted as a genetic disease. This thesis challenges this assumption and proposes that cancer be considered as an emergent complex system. A new framework for carcinogenesis and cancer progression is presented. This framework is applied to identify biological markers with the potential to predict recurrence in oral cancer. A simple dual staining technique is developed to test the identified biomarkers. The results support the use of these biomarkers as a predictor of recurrence over and above traditionally measured cancer clearance.
Vision to reality: From Robert R. Wilson's frontier to Leon M. Lederman's Fermilab
Creators: name: Hoddeson, Lillian H.
name: Kolb, Adrienne W.
Publisher: name: arXiv
Year: 2011
Subjects: subject: History and Philosophy of Physics (physics.hist-ph)
subject: FOS: Physical sciences

description: This paper examines the roles of vision and leadership in creating and directing Fermi National Accelerator Laboratory from the late 1960s through the 1980s. The story divides into two administrations having different problems and accomplishments, that of Robert R. Wilson (1967-1978), which saw the transformation from cornfield to frontier physics facility, and that of Leon Max Lederman (1979-1989), in which the laboratory evolved into one of the world's major high-energy facilities. Lederman's pragmatic vision of a user-based experimental community helped him to convert the pioneering facility that Wilson had built frugally into a laboratory with a stable scientific, cultural, and funding environment.
title: Das Übersetzen medizinischer Befunde in laienverständliche Sprache verbessert die Kommunikationsfähigkeit von Medizinstudierenden – eine Pilotstudie
Creators: name: Bittner, Anja
name: Jonietz, Ansgar
name: Bittner, Johannes
name: Beickert, Luise
name: Harendza, Sigrid
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Medizinische Sachverhalte für Patienten verständlich zu erklären ist wesentlich für eine erfolgreiche Behandlung. Nur wenn Patienten die für sie relevanten Aspekte ihrer Erkrankung verstehen, können sie aktiv an ihrem Heilungsprozess mitwirken.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Investigation of Type I Interferon and Immune Signalling in Breast and Ovarian Cancer
Creators: name: ZOE REBECCA CHURCH MARKS
Publisher: name: Monash University
Year: 2019
Subjects: subject: Cancer
subject: 110709 Tumour Immunology
subject: FOS: Clinical medicine
subject: 111201 Cancer Cell Biology
subject: Immunology

description: Cancer metastasis occurs as a result of poorly defined co-ordinated signals throughout the body. This thesis investigates the complex interactions between tumour cells and proteins called type I interferons (IFN), which can suppress tumour progression either directly or indirectly, by activating immune responses. My results show that these signals are detectable in blood during the spread of breast cancer, reflecting immune changes occurring in primary tumours and metastatic potential. Additionally, this work reveals an unusual type I IFN, IFN, plays a role in suppressing ovarian cancer development and further, has therapeutic potential against the spread of this cancer.
Ausstellungskalender
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 12 Nr. 12 (1959): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
The Epigenetic Control of Mitochondrial DNA Copy Number in Tumorigenesis and Differentiation
Creators: name: XIN SUN
Publisher: name: Monash University
Year: 2018
Subjects: subject: 111203 Cancer Genetics
subject: FOS: Clinical medicine
subject: 60404 Epigenetics (incl. Genome Methylation and Epigenomics)
subject: FOS: Biological sciences

description: This thesis focuses on how the communication between the two genomes within a cell, namely the nuclear and mitochondrial genomes, is disrupted in cancer. It identifies abnormal levels in modifications to both genomes, as determined by the levels of DNA methylation, which regulate the number of mitochondrial DNA copies in a cancer cell. It suggests that a cell needs to establish harmony between these two genomes and provides potential implications for cancer treatments.
The Regulation and Function of the Y-Chromosome Gene, SRY, in the Healthy and Diseased Male Brain
Creators: name: HANNAH PUI YUN LOKE
Publisher: name: Monash University
Year: 2019
Subjects: subject: Behavioral Neuroscience
subject: 60105 Cell Neurochemistry
subject: FOS: Biological sciences
subject: Genetics

description: This thesis investigated the role of a male-specific Y-chromosome gene known as SRY in the male brain. The findings revealed that SRY is involved in the healthy functioning of the male brain. However, high levels of SRY worsen the symptoms in animal models of Parkinson’s disease. In contrast, low levels of SRY contributed to symptoms in an animal model of attention deficit hyperactivity disorder (ADHD). Therefore, the results demonstrate that the misregulation of SRY levels could underlie the male bias in brain disorders such as Parkinson’s disease and ADHD.
title: Reden können wir alle! Können wir alle miteinander reden?
Creators: name: Dürsch, Markus
name: Keil, Stephanie
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Ziel des Projektes war die Einbindung von simulierten Patientengesprächen in das Blockpraktikum Innere Medizin 1 des UKR mit den Inhalten „Arzt-Patienten-Kommunikation mit dem Schwerpunkt auf allgemein verständliche Vermittlung von medizinischen Inhalten“.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Effect of Helicobacter pylori Interactions with Host Epithelial Cells on Inflammation and Disease
Creators: name: KIMBERLEY NATALIE D COSTA
Publisher: name: Monash University
Year: 2019
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Immunology
subject: FOS: Clinical medicine

description: This thesis describes a characterization of the novel mechanisms by which Helicobacter pylori interacts with host cells and the roles of these interactions in its establishment of infection and persistence in the human gastric mucosa.
Innate immunity of mice to Hendra virus infection
Creators: name: EMMA LOUISE CROSER
Publisher: name: Monash University
Year: 2019
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: 110707 Innate Immunity
subject: FOS: Clinical medicine

description: Hendra virus (HeV) causes severe infection in a broad range of species leading to mortality in both humans and animals. Productive HeV infection occurred in wild type and mice deficient in interferon signalling (the body’s antiviral defence mechanism). But, unlike other animal species susceptible to HeV infection severe disease did not develop. Therefore the restriction of fulminating disease cannot be attributed solely to the efficacy of mouse interferon signalling pathways against HeV-mediated anti-interferon mechanisms. Little neutralising antibody response was seen, suggesting an innate response mechanism remains relevant to limiting the systemic effects of infection. IFITM proteins were possible candidates but replication and cytopathic effect continued in their presence.
Examining the Impact of Game-Based Learning on Student Engagement and Performance in an Introductory Computer Programming Course at the University of the Southern Caribbean (USC)
Creators: name: St.Bernard, Fayola
Publisher: name: Lancaster University
Year: 2023

description: At the University of the Southern Caribbean (USC) students often struggle with learning programming. Because of this struggle, they often become disengaged with the programming courses, with some transferring to other degree programmes or withdrawing from the programme. While several strategies have been used to ensure that students can problem- solve, design, and develop coded solutions, it has not been enough to alleviate the issues. Game- based learning (GBL) emerged as a possible strategy that can potentially help students develop these skills while keeping them engaged with the course content. Implementing such a strategy within the department requires evidence that it can be an effective technique for teaching and learning programming. Therefore, the aim of this study is to evaluate the impact of GBL on student engagement and overall performance in an introductory programming course. The research was designed as a deductive exploratory single case study research strategy and method. It approaches the aims and objectives from a pragmatic perspective, and as a result, uses a mixed methodological approach to data collection and analysis. The findings show that while GBL does not alleviate the common negative reactions to learning programming, it does provide a learning environment engaging enough for students to overlook these. This results in students having an enhanced perception of the knowledge and improved performance. In implementing GBL in other programming courses, some features that are potentially the most impactful on students learning are immediate feedback, freedom to fail, user interface, code without limitations, and a visual representation of progress.
Computing covariant vectors, Lyapunov vectors, Oseledets vectors, and dichotomy projectors: a comparative numerical study
Creators: name: Froyland, Gary
name: Hüls, Thorsten
name: Morriss, Gary P.
name: Watson, Thomas M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics

description: Covariant vectors, Lyapunov vectors, or Oseledets vectors are increasingly being used for a variety of model analyses in areas such as partial differential equations, nonautonomous differentiable dynamical systems, and random dynamical systems. These vectors identify spatially varying directions of specific asymptotic growth rates and obey equivariance principles. In recent years new computational methods for approximating Oseledets vectors have been developed, motivated by increasing model complexity and greater demands for accuracy. In this numerical study we introduce two new approaches based on singular value decomposition and exponential dichotomies and comparatively review and improve two recent popular approaches of Ginelli et al. (2007) and Wolfe and Samelson (2007). We compare the performance of the four approaches via three case studies with very different dynamics in terms of symmetry, spectral separation, and dimension. We also investigate which methods perform well with limited data.
Investigation of the pathophysiology of granulosa cell tumours of the ovary
Creators: name: TAN HUNG LEUNG
Publisher: name: Monash University
Year: 2019
Subjects: subject: Cancer
subject: 111207 Molecular Targets
subject: FOS: Clinical medicine
subject: 110199 Medical Biochemistry and Metabolomics not elsewhere classified
subject: Molecular Biology
subject: 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
subject: FOS: Biological sciences
subject: 111203 Cancer Genetics
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

description: This research project investigates the effects of an innovative drug combination in the treatment of granulosa cell tumours (GCT) of the ovary. Using tumour cells derived from cancer patients and state-of-the-art technologies, we examined the growth, cell death and other changes induced by the two drugs, Smac mimetics and rosiglitazone. We found that these two drugs work co-operatively to impair metabolism of the cancer cells and their ability to spread. Subsequently, cancer cell growth ceased and cell death was observed. These promising pre-clinical data support further investigation into the combined treatment as cancer therapeutic in GCT.
Personalised medicine for pancreatic cancer: using endoscopic ultrasound-guided biopsy for the development of a personalised pre-clinical model of disease
Creators: name: WILLIAM ARCHER BERRY
Publisher: name: Monash University
Year: 2019
Subjects: subject: Cancer
subject: 111207 Molecular Targets
subject: FOS: Clinical medicine
subject: 111203 Cancer Genetics
subject: 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)

description: While pancreatic cancer is a genetically heterogeneous disease, 90% of patients exhibit mutations in KRAS. Most patients also respond poorly to generalised treatments, suggesting that patient outcomes may depend on genetic profiling and personalised therapeutic approaches. A potential role for those approaches is explored here, using tumour tissue procured from patients via a minimally invasive sampling technique to test for KRAS mutation status and whether KRAS mutation influenced tumour response to treatment. Only KRAS wild-type tumours were sensitive to the drug. These techniques allow for rapid translational research, from biomarker discovery to clinical trials.
title: Veränderung in Wahrnehmung und Akzeptanz von Peer-Feedback – Wege in Richtung Feedbackkultur
Creators: name: Raski, Bianca
name: Eißner, Alexander
name: Berger, Ralp
name: Schneider, Matthias
name: Rotthoff, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Das Peer-Feedback (P-FB) soll bei Studierenden der Humanmedizin der HHUD ein Abgleich der Selbsteinschätzung (SE) zu Fragen der persönlichen und beruflichen Entwicklung mit den Einschätzungen der KommilitonInnen ermöglichen, was zur Reflexion anregen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
The Primeval Populations of the Ultra-Faint Dwarf Galaxies
Creators: name: Brown, Thomas M.
name: Tumlinson, Jason
name: Geha, Marla
name: Kirby, Evan N.
name: VandenBerg, Don A.
name: Munoz, Ricardo R.
name: Kalirai, Jason S.
name: Simon, Joshua D.
name: Avila, Roberto J.
name: Guhathakurta, Puragra
name: Renzini, Alvio
name: Ferguson, Henry C.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present new constraints on the star formation histories of the ultra-faint dwarf (UFD) galaxies, using deep photometry obtained with the Hubble Space Telescope (HST). A galaxy class recently discovered in the Sloan Digital Sky Survey, the UFDs appear to be an extension of the classical dwarf spheroidals to low luminosities, offering a new front in efforts to understand the missing satellite problem. They are the least luminous, most dark-matter dominated, and least chemically-evolved galaxies known. Our HST survey of six UFDs seeks to determine if these galaxies are true fossils from the early universe. We present here the preliminary analysis of three UFD galaxies: Hercules, Leo IV, and Ursa Major I. Classical dwarf spheroidals of the Local Group exhibit extended star formation histories, but these three Milky Way satellites are at least as old as the ancient globular cluster M92, with no evidence for intermediate-age populations. Their ages also appear to be synchronized to within ~1 Gyr of each other, as might be expected if their star formation was truncated by a global event, such as reionization.
description: Accepted for publication in The Astrophysical Journal Letters. Latex, 5 pages, 2 color figures, 1 table
title: Integration von E-Learning-Angebote anderer Lehrbereiche in den QB Notfallmedizin zur Förderung des interdisziplinären und interprofessionellen Dialogs: Evaluationsergebnisse
Creators: name: Ahne, Thomas
name: Von Poellnitz, Paul
name: Gaupp, Rainer
name: Giesler, Marianne
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Das 2-tägige Blockpraktikum Notfallmedizin des QB 8 wird seit Jahren sehr gut evaluiert. Es wurden mehrfach strukturell-organisatorische Veränderungen durchgeführt: Eine Kürzung von 3 auf 2 Tage sowie eine Verlagerung aus dem 10. ins 5. Fachsemester machten weitreichende[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Oscillatory motions observed in eruptive filaments
Creators: name: Bocchialini, K.
name: Baudin, F.
name: Koutchmy, S.
name: Pouget, G.
name: Solomon, J.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: Context: The origin of the variable component of the solar wind is of great intrinsic interest for heliophysics and space-weather, e.g. the initiation of coronal mass ejections, and the problem of mass loss of all stars. It is also related to the physics of coronal neutral sheets and streamers, occurring above lines of magnetic polarity reversal. Filaments and prominences correspond to the cool coronal component of these regions. Aims: We examine the dynamical behaviour of these structures where reconnection and dissipation of magnetic energy in the turbulent plasma are occurring. The link between the observed oscillatory motions and the eruption occurrence is investigated in detail for two different events. Method: Two filaments are analysed using two different datasets: time series of spectra using a transition region line (He I at 584.33 A) and a coronal line (Mg X at 609.79 A) measured with CDS on-board SOHO, observed on May 30, 2003, and time series of intensity and velocity images from the NSO/Dunn Solar Telescope in the Halpha line on September 18, 1994 for the other. The oscillatory content is investigated using Fourier transform and wavelet analysis and is compared to different models. Results: In both filaments, oscillations are clearly observed, in intensity and velocity in the He I and Mg X lines, in velocity in Halpha, with similar periods from a few minutes up to 80 minutes, with a main range from 20 to 30 minutes, cotemporal with eruptions. Both filaments exhibit vertical oscillating motions. For the filament observed in the UV (He I and Mg X lines), we provide evidence of damped velocity oscillations, and for the filament observed in the visible (Halpha line), we provide evidence that parts of the filament are oscillating, while the filament is moving over the solar surface, before its disappearance.
description: Accepted in A&A
R. Hamann-Mac Lean und H. Hallensleben, Die Monumentalmalerei in Serbien und Makedonien vom 11. bis zum frühen 14. Jahrhundert - H. Hallensleben, Die Malerschule des Königs Milutin
Creators: name: Belting, Hans
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Rezension zu: R. Hamann-Mac Lean und H. Hallensleben, Die Monumentalmalerei in Serbien und Makedonien vom 11. bis zum frühen 14. Jahrhundert. Bildband (Osteuropastudien der Hochschulen des Landes Hessen. Reihe II, Band 3) (Gießen 1963) 40 S., 354 Abb. auf Taf., 1 Farbtaf. und 36 Faltpläne. H. Hallensleben, Die Malerschule des Königs Milutin (Osteuropastudien der Hochschulen des Landes Hessen. Reihe II, Band 5) (Gießen 1963) 184 S., 6 Taf.
description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 21 Nr. 5 (1968): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Anti-inflammatory strategies towards necrotising enterocolitis
Creators: name: Cho, Steven Shian Chin
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Necrotising enterocolitis (NEC) is a severe gastrointestinal disease that affects predominantly preterm infants. Despite all the research efforts that have been directed at NEC over the last few decades, its mortality remains high, its pathogenesis remains unclear, and the therapeutic strategies available for its treatment have changed little. As a result, the global burden of NEC continues to grow in parallel with the rise in the preterm infant population achieved through improvements and access to medical technology such mechanical ventilation and use of surfactants. My thesis sought to unravel the complex immune pathways that are critical for NEC pathogenesis and to address an urgent unmet need to identify novel and effective therapeutics for NEC.
Weak-interaction mediated rates on iron isotopes for presupernova evolution of massive stars
Creators: name: Nabi, Jameel-Un
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: During the presupernova evolution of massive stars, the isotopes of iron, $^{54,55,56}$Fe, are advocated to play a key role inside the cores primarily decreasing the electron-to-baryon ratio ($Y_{e}$) mainly via electron capture processes thereby reducing the pressure support. Electron decay and positron capture on $^{55}$Fe, on the other hand, also has a consequential role in increasing the lepton ratio during the silicon burning phases of massive stars. The neutrinos and antineutrinos produced, as a result of these weak-interaction reactions, are transparent to the stellar matter and assist in cooling the core thereby reducing the entropy. The structure of the presupernova star is altered both by the changes in $Y_{e}$ and the entropy of the core material. The aim of this paper is to report the improved microscopic calculation of Gamow-Teller (GT$_{\pm}$) strength distributions of these key isotopes of iron using the pn-QRPA theory. The main improvement comes from the incorporation of experimental deformation values for these nuclei. Additionally six different weak-interaction rates, namely electron & positron capture, electron & positron decay, and, neutrino & antineutrino cooling rates, were also calculated in presupernova matter. The calculated electron capture and neutrino cooling rates due to isotopes of iron are in good agreement with the large-scale shell model (LSSM) results. The calculated beta decay rates, however, are suppressed by three to five orders of magnitude.
description: 11 pages, 4 figures, 4 tables
Computing Optimal Cycle Mean in Parallel on CUDA
Creators: name: Barnat, Jiří
name: Bauch, Petr
name: Brim, Luboš
name: Češka, Milan
Publisher: name: arXiv
Year: 2011
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: Computation of optimal cycle mean in a directed weighted graph has many applications in program analysis, performance verification in particular. In this paper we propose a data-parallel algorithmic solution to the problem and show how the computation of optimal cycle mean can be efficiently accelerated by means of CUDA technology. We show how the problem of computation of optimal cycle mean is decomposed into a sequence of data-parallel graph computation primitives and show how these primitives can be implemented and optimized for CUDA computation. Finally, we report a fivefold experimental speed up on graphs representing models of distributed systems when compared to best sequential algorithms.
description: In Proceedings PDMC 2011, arXiv:1111.0064
Ausstellungskalender
Creators: name: Redaktion, Die
Publisher: name: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
Year: 2020

description: Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege, Bd. 21 Nr. 6 (1968): Kunstchronik. Monatsschrift für Kunstwissenschaft, Museumswesen und Denkmalpflege
title: Evaluation des Lehrformats „Interprofessionelle Übungseinheit“
Creators: name: Mette, Mira
name: Dölken, Mechthild
name: Magosch, Petra
name: Hinrichs, Jutta
name: Narciß, Elisabeth
name: Schüttpelz-Brauns, Katrin
name: Fritz, Harald M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Das Lehrformat „Interprofessionelle Übungseinheit“ wurde im Rahmen eines von der Robert Bosch Stiftung geförderten Projekts entwickelt und im Wintersemester 2014/2015 an der Universitätsmedizin Mannheim erprobt. In dieser Übungseinheit[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Thienemanniella Kieffer 1911
Creators: name: Armitage, Brian J.
name: Andersen, Trond
name: Giłka, Wojciech
name: Castillo Sánchez, Kayla N.
name: Ríos González, Tomás A.
name: Aguirre, Yusseff P.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Thienemanniella

description: Genus Thienemanniella Kieffer, 1911
A genus of ~55 named species that occur in all zoogeographical regions except Antarctica. The Neotropical species were reviewed by Wiedenbrug et al. (2013). The larvae occur in most lotic habitats, from fast-flowing streams to slow-flowing ditches and rivers (Andersen et al. 2013).
description: Published as part of Armitage, Brian J., Andersen, Trond, Giłka, Wojciech, Castillo Sánchez, Kayla N., Ríos González, Tomás A. & Aguirre, Yusseff P., 2025, The Diptera of Panama. II. A first benchmark for the family Chironomidae, pp. 201-240 in Zootaxa 5613 (2) on page 226, DOI: 10.11646/zootaxa.5613.2.1, http://zenodo.org/record/15224174
title: Expertenwissen in der Anästhesie – eine experimentelle Studie
Creators: name: Umminger, Hannah
name: Schulze, Johannes
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Entscheidungen von erfahrenen Experten zeichnen sich durch Geschwindigkeit und Zuverlässigkeit aus; dabei ist oft unklar, auf welcher Datenbasis diese Entscheidungen getroffen werden. Bisherige Untersuchungen, insbesondere bei technischen Berufen mit Ja/Nein-Entscheidungen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
title: Expertenentscheidung in der Medizin – Studiendesign und erste Ergebnisse
Creators: name: Umminger, Hannah
name: Lodders, Stefanie
name: Pape, Judith
name: Schulze, Johannes
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Fragestellung/Einleitung: Die Fähigkeit von Experten, schnell und richtig Entscheidungen treffen zu können, wird immer wieder untersucht. Dabei sind nur wenige Untersuchungen in der Medizin durchgeführt worden, obwohl das Interesse an diesen Entscheidungsmechanismen groß ist.[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA) und des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ)
Destabilizing Tachyonic Vacua at or above the BF Bound
Creators: name: Kanno, Sugumi
name: Sasaki, Misao
name: Soda, Jiro
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: It is well known that tachyonic vacua in an asymptotically Anti-de Sitter (AdS) space-time are classically stable if the mass squared is at or above the Breitenlohner and Freedman (BF) bound. We study the quantum stability of these tachyonic vacua in terms of instantons. We find a series of exact instanton solutions destabilizing tachyonic state at or above the BF bound in asymptotically AdS space. We also give an analytic formula for the decay rate and show that it is finite. Comparing our result with the well-known algebraic condition for the stability, we discuss stability conditions of tachyonic vacua at or above the BF bound.
description: 11 pages, 6 figures
Near-infrared Spectroscopy of GRB Host Galaxies at z >~ 1.5: Insights into Host Galaxy Dynamics and Interpretations of Afterglow Absorption Spectra
Creators: name: Chen, Hsiao-Wen
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: This paper presents near-infrared echellette spectra of faint galaxies in the fields around GRB 050820A at redshift z=2.613 and GRB 060418 at z=1.490. The spectroscopic data show that both GRBs originate in a dynamic environment of interacting galaxies separated by < 15 h^{-1} kpc in projected distance and |dv|
description: 10 pages, 6 figures, accepted for publication in MNRAS