cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Klotho expression in cardiomyocytes in patients at a higher atherosclerotic cardiovascular disease risk
Creators: name: Corsetti, Giovanni
name: Pasini, Evasio
name: Romano, Claudia
name: Scarabelli, Tiziano
name: Agrawal, Pratik A.
name: Ferrari-Vivaldi, Mario
name: Assanelli, Deodato
name: Flati, Vincenzo
name: Dioguardi, Francesco S.
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Klotho; FGFs; atherosclerotic cardiovascular disease risk; human cardiomyocytes

description: Klotho proteins (α- and β-Klotho) are transmembrane proteins whose extracellular domain is secreted into blood and urine by ectodomain shedding. As such they behave as circulating proteins that regulate cell metabolism, endothelial function and calcium homeostasis, as well as modulating the lifespan connected activity of Fibroblast Growth Factors (FGFs, mainly 21 and 23) and other molecules (1). Recent data have shown that highest levels of plasma circulating Klotho are associated with a lower cardiovascular risk, thereby suggesting a possible role for Klotho in cardiovascular diseases (2). However, although Klotho has been identified in various organs, including kidney, brain, adipose tissue and intestine, it is unknown whether cardiomyocytes express Klotho and FGFs and, if so, whether high cardiovascular risk can be associated with cardiac expression of Klotho, FGFs and other related molecules. We examined myocardial biopsies from 20 patients with an estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk in the range of 5% to 7.5% and 10 age-matched control subjects with an estimated 10-year ASCVD risk of <5% (3) undergoing cardiac surgery other than coronary artery by-pass. Both groups of patients were statin naive, had normal hemoglobin A1c, normal coronary arteries on left heart catheterization, and had LDL cholesterol levels between 70 and 189 mg/ DL. Using immunohistochemistry methods, we evaluated Klotho and FGFs expression in human cardiomyocytes, and whether higher ASCVD risk influenced the expression of other molecules involved in endoplasmic reticulum stress (GRP78), oxidative stress (SOD1, NFkB) and inflammation (iNOS, eNOS). Cardiomyocytes of patients with a higher ASCVD risk exhibited lower expression of Klotho, but also higher expression of FGFs, as compared to cardiomyocytes of patients with a reduced ASCVD risk. Furthermore, higher ASCVD risk was associated with significantly increased expression of GRP78, SOD1, NFkB and iNOS (all p<0.05). This study shows for the first time that Klotho proteins are inherently expressed in human cardiomyocytes and also that cardiac expression of Klotho is down regulated in higher ASCVD risk patients, while the expression of FGFs and other stress-related molecules involved in myocyte damage, such as GRP78, SOD1, NFkB and iNOS, is significantly increased. Further studies are warranted to investigate the association of klotho, FGFs and related molecules expression with cardiovascular risk.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Systemic sclerosis-like histopathological features in the myocardium of uPAR-deficient mice
Creators: name: Manetti, Mirko
name: Rosa, Irene
name: Fazi, Marilena
name: Carmeliet, Peter
name: Matucci-Cerinic, Marco
name: Manneschi, Lidia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Systemic sclerosis; Animal model; Myocardium; uPAR

description: Systemic sclerosis (SSc) is a complex connective tissue disease characterized by widespread microvascular damage and progressive fibrosis involving the skin and multiple internal organs, especially lungs, heart and gastrointestinal tract. Cardiomyopathy is among the leading causes of death in SSc patients. Urokinase-type plasminogen activator receptor (uPAR)-deficient mice have been recently reported to display important histopathological hallmarks of SSc, including dermal fibrosis, reduced dermal capillary density and pulmonary fibrosis (Manetti et al., 2014). Here, we investigated whether uPAR-deficient mice could display the histopathological features of SSc-related cardiomyopathy. Left ventricular myocardium specimens from uPAR-deficient and wild-type mice were processed for light and transmission electron microscopy. Myocardium sections were stained with hematoxylin-eosin and Picrosirius red for the analysis of collagen content. Myofibroblast and microvessel counts were determined by immunofluorescence for alpha-smooth muscle actin and CD31, respectively. Endothelial cell apoptosis was assessed by a combined TUNEL/CD31 immunofluorescence assay. The expression of uPAR in human SSc and control left ventricular myocardium samples was determined by immunohistochemistry. The myocardium of uPAR-deficient mice displayed focal ischemic lesions with cardiomyocyte hypertrophy, myofibril rarefaction and contraction band necrosis. Interstitial and perivascular collagen deposition and myofibroblast counts were significantly greater in myocardial tissue of uPAR-deficient than in wild-type mice. In uPAR-deficient mice, myocardial fibrosis was paralleled by microvascular endothelial cell apoptosis and reduced capillary density. uPAR expression was significantly downregulated in human SSc myocardium. Typical histopathological features of SSc-related cardiomyopathy are mimicked by uPAR-deficient mice. The downregulation of uPAR in the myocardium of SSc patients may suggest similar underlying pathogenetic mechanisms. uPAR-deficient mice might be a preclinical model to study the mechanisms and therapeutic approaches of myocardial involvement in SSc.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
Dipyridamole increases Cx43 expression in heart muscle cells through Adenosine 2A receptor/PKC pathway
Creators: name: Bianchi, Francesco
name: Moscato, Stefania
name: Ippolito, Chiara
name: Dini, Sauro
name: Sabbatini, Antonietta R.M.
name: Dolfi, Amelio
name: Mattii, Letizia
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Heart cells; Cx43; PKC; adenosine receptor; dipyridamole

description: Cx43, a predominant connexin in the heart, forms gap junctions (GJs) that facilitate electrical cell-cell coupling and hemichannels that represent a pathway for the exchange of ions and metabolites between cytoplasm and the extracellular milieu. Our recent results (1) demonstrated that an altered distribution and quantitative expression of factors involved in Cx43-made GJ regulation as Cx43, its phosphorylated form pS368-Cx43, PKC phosphorylated substrates, and adenosine 2A receptor (A2AR) are present in ventricular myocardium with left ventricular dysfunction. Moreover, dipyridamole treatment, which shows a mild protective role on left ventricular function, seems to act through re-modulating the expression and activation of these factors. The role of these factors on signal transduction cascade triggered by dipyridamole was evaluated in this study by pharmacological and immunoistochemical experiments using the rat cardiomyoblast cell line H9c2. The treatment of H9c2 cells with dipyridamole enhanced the expression of Cx43, A2AR and PKC activity while induced a decrease of pS368-Cx43. Interestingly, we found that the A2AR activation was a prerequisite for the effects of dipyridamole, in fact, the pre-treatment with CSC, a selective A2AR receptor antagonist, abolished its effects on the expression of these factors.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
GCRT J1742-3001: A New Radio Transient Towards the Galactic Center
Creators: name: Hyman, Scott D.
name: Wijnands, Rudy
name: Lazio, T. Joseph W.
name: Pal, Sabyasachi
name: Starling, Rhaana
name: Kassim, Namir E.
name: Ray, Paul S.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We report the detection of a new transient radio source, GCRT J1742-3001, located ~1 degree from the Galactic center. The source was detected ten times from late 2006 to 2007 May in our 235 MHz transient monitoring program with the Giant Metrewave Radio Telescope (GMRT). The radio emission brightened in about one month, reaching a peak observed flux density of ~100 mJy on 2007 January 28, and decaying to ~50 mJy by 2007 May when our last monitoring observation was made. Two additional faint, isolated 235 MHz detections were made in mid-2006, also with the GMRT. GCRT J1742-3001 is unresolved at each epoch, with typical resolutions of ~20 arcsec x 10 arcsec. No polarization information is available from the observations. Based on nondetections in observations obtained simultaneously at 610 MHz, we deduce that the spectrum of GCRT J1742-3001 is very steep, with a spectral index less than about -2. Follow-up radio observations in 2007 September at 330 MHz and 1.4 GHz, and in 2008 February at 235 MHz yielded no detections. No X-ray counterpart is detected in a serendipitous observation obtained with the X-ray telescope aboard the Swift satellite during the peak of the radio emission in early 2007. We consider the possibilities that GCRT J1742-3001 is either a new member of an existing class of radio transients, or is representative of a new class having no associated X-ray emission.
description: 19 pages, 3 figures, submitted to ApJ
Fractal analysis of alveolarization in hyperoxia-induced rat models of bronchopulmonary dysplasia
Creators: name: Porzionato, Andrea
name: Guidolin, Diego
name: Macchi, Veronica
name: Sarasin, Gloria
name: Rambaldo, Anna
name: Grisafi, Davide
name: Dedja, Arben
name: Tortorella, Cinzia
name: Zaramella, Patrizia
name: De Caro, Raffaele
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Morphometry; Fractal analysis; bronchopulmonary dysplasia

description: Many morphometric approaches have been proposed for quantitative evaluation of alveolarization in experimental models of bronchopulmonary dysplasia (BPD), such as alveolar number, alveolar size and variability, mean linear intercept (Lm), surface-to-volume ratio, or radial alveolar count. Conversely, no papers are available about potentiality of fractal analysis in this matter. Thus, in the present study, we performed a comparative analysis between Lm and fractal parameters (fractal dimension (D) and lacunarity (λ)), in experimental hyperoxia-induced models of BPD. At birth the newborn rats were randomly distributed between the following experimental groups: a) rats raised in ambient air for 2 weeks; b) exposed to 60% oxygen for 2 weeks; c) raised in normoxia for 6 weeks; d) exposed to 60% hyperoxia for 2 weeks and then to room air for further 4 weeks. Normoxic 6-weeks rats showed a significant decrease of Lm and a significant increase of D and λ with respect to normoxic 2-weeks rats, indicative of alveolar development. Hyperoxia-exposed rats of 2 weeks did not show significant changes in Lm and D with respect to normoxic rats equal in age, although λ was significantly lower in hyperoxic group. Conversely, in the comparison between 6-week rats, the hyperoxia-exposed group showed higher value of Lm and lower values of D and λ, when compared to the normoxic group, confirming a lower alveolar gas exchange surface-to-volume ratio and an airspace morphology of lower complexity. The analysis of the ROC curves showed a comparable discriminatory power of Lm and D as binary classifiers of the airspace morphology (areas under the curves of 0.815 and 0.753, respectively). Moreover, the values exhibited by the parameters when different segmentation thresholds were applied suggested that fractal parameters are less sensitive (D and λ showed a coefficient of variation of 0.005 and 0.009, respectively) than Lm (exhibiting a coefficient of variation of 0.05) to the bias eventually introduced in the analysis by approximations or errors in tissue segmentation. In conclusion, the present study demonstrated the ability of fractal analysis (D and λ) to identify developmental and hyperoxia-induced changes in alveolarization with discriminatory power similar to Lm. The fractal approach, however, appears more fit to automatic image analysis, being less influenced by approximations in thresholding and image editing.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
A multi-scale investigation of biological niches within human calcified aortic valves helps to understand the pathological biomineralization process
Creators: name: Relucenti, Michela
name: Cottignoli, Valentina
name: Agrosì, Giovanna
name: Cavarretta, Elena
name: Salvador, Loris
name: Battaglione, Ezio
name: Maras, Adriana
name: Familiari, Giuseppe
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Scanning electron microscopy; aortic valve; calcification

description: Calcific aortic valve stenosis (CAVS) is the most common form of heart valve disease in the industrialized countries, being an important public health problem [1]. Ectopic calcifications within aortic valve leaflets are strictly associated with CAVS, interfering with cusps opening, they lead to ventricular outflow obstruction [2]. Up to date no proven medical therapy stops CAVS course progression, so valve replacement is the only possible treatment of severe CAVS. Unfortunately, the degenerative valve calcification process, affects also bioprosthetic implants [3]. Being the molecular mechanisms leading to valve calcification still not understood, our aim was to carry on a multi-scale investigation using Scanning Electron Microscopy, Transmission Electron Microscopy and Energy Dispersive X-ray Spectrometry, to provide new insights into calcification process. Severely calcified aortic (tricuspid type, n = 29; bicuspid type, n = 3) and mitral valves (n = 4) were obtained from patients of both sexes (males=25) and different ages (mean age 72±10, range 41-90 years old) undergoing valve replacement due to severe aortic and mitral valve stenosis. We detected bioapatite crystals in two different mineralization sites: niches and extracellular matrix. This suggests the action of two different growth processes: the first occurs in biological niches and it is ascribed to a purely physico-chemical process; the second has the extracellular matrix acting ass the template for a site-directed nanocrystals nucleation. Different shapes of bioapatite crystallization were observed at micrometer scale in each microenvironment but at the nanoscale level crystals appear made up by the same subunits. We suggest that bioapatite nanocrystals in heart valve may activate a strong inflammatory process leading to irreversible pathological condition that, once activated,may aggravate the inflammatory response against bioapatite nanocrystals leading to a severe calcification process.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
title: ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ Â«ÐÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÐºÐ¾Ð½ÑÑÐ¾Ð»ÑÂ» Ð½Ð° Ð Ð Ð¸ Ð² Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÑ , Ð¾ÑÐ½Ð°ÑÐµÐ½Ð½ÑÑ ÐÐ­ÐÐ, Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸ÑÑ , Ð¿Ð¾Ð´Ð²ÐµÐ´Ð¾Ð¼ÑÑÐ²ÐµÐ½Ð½ÑÑ ÐÐ¸Ð½Ð¾Ð±ÑÐ½Ð°ÑÐºÐ¸ Ð Ð¾ÑÑÐ¸Ð¸
title: ÑÑÐµÐ±Ð½Ð¾-Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸
titleType: Subtitle
Creators: name: Ð¡Ð°Ð»ÐºÑÑÐ°Ð½, ÐÐ»Ð°Ð´Ð¸Ð¼Ð¸Ñ
Publisher: name: ÐÐÐÐÐ¢ÐÐ¥-ÐÐ ÐÐ¡Ð¡
Year: 2023
Subjects: ÐÑ ÑÐ°Ð½Ð° ÑÑÑÐ´Ð°

description: Ð ÑÑÐµÐ±Ð½Ð¾-Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸ÑÑ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð¸ Ð¼ÐµÑÐ¾Ð´Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¾ÑÐ½Ð¾Ð²Ñ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Â«ÐÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÐºÐ¾Ð½ÑÑÐ¾Ð»ÑÂ» Ð½Ð° Ð Ð Ð¸
Ð² Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÑ, Ð¾ÑÐ½Ð°ÑÐµÐ½Ð½ÑÑ ÐÐ­ÐÐ, Ð² Ð²ÑÑÑÐ¸Ñ ÑÑÐµÐ±Ð½ÑÑ Ð·Ð°Ð²ÐµÐ´ÐµÐ½Ð¸ÑÑ, Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ Ð¸ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÐ»Ð¾Ð²Ð¸Ð¹ ÑÑÑÐ´Ð° Ð¾Ð¿ÐµÑÐ°ÑÐ¾ÑÐ¾Ð² ÐÐ­ÐÐ Ð½Ð° Ð¸Ñ ÑÐ°Ð±Ð¾ÑÐ¸Ñ Ð¼ÐµÑÑÐ°Ñ Ð¸ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½Ð¾-Ð¿ÑÐ°Ð²Ð¾Ð²ÑÑ Ð°ÐºÑÐ¾Ð², Ð¿ÑÐµÐ´ÑÑÐ²Ð»ÑÐµÐ¼ÑÑ Ðº Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÐ¼, ÑÐ²ÐµÑÐ¾Ð²Ð¾Ð¹ ÑÑÐµÐ´Ðµ Ð² Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÑ Ð¸ Ð½Ð° ÑÐ°Ð±Ð¾ÑÐµÐ¼ Ð¼ÐµÑÑÐµ, ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ ÑÑÐ³Ð¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ð¼ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ð¹, Ð¿ÑÐµÐ´ÑÑÐ²Ð»ÑÐµÐ¼ÑÑ Ðº ÐºÐ¾Ð¼Ð¿ÑÑÑÐµÑÐ½Ð¾Ð¹ Ð¼ÐµÐ±ÐµÐ»Ð¸, ÐºÐ¾Ð¼Ð¿Ð¾Ð½ÐµÐ½ÑÐ°Ð¼ ÐÐ­ÐÐ, ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ð¼ ÑÐ°ÐºÑÐ¾ÑÐ°Ð¼ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ ÑÑÐµÐ´Ñ, Ð° ÑÐ°ÐºÐ¶Ðµ ÑÐ°ÐºÑÐ¾ÑÐ°Ð¼ ÑÑÑÐ´Ð¾Ð²Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ° (Ð½Ð°Ð¿ÑÑÐ¶ÐµÐ½Ð½Ð¾ÑÑÑ Ð¸ ÑÑÐ¶ÐµÑÑÑ ÑÑÑÐ´Ð°) Ð² ÑÐµÐ»ÑÑ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð¸Ñ ÐºÐ¾Ð»Ð¸ÑÐµÑÑÐ²Ð° Ð¸ Ð¿ÑÐ¾Ð´Ð¾Ð»Ð¶Ð¸ÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÐ³Ð»Ð°Ð¼ÐµÐ½ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð½ÑÑ Ð¿ÐµÑÐµÑÑÐ²Ð¾Ð² Ð¿ÑÐ¸ ÑÐ°Ð±Ð¾ÑÐµ Ñ ÐÐ­ÐÐ. Ð£ÑÐµÐ±Ð½Ð¾-Ð¼ÐµÑÐ¾Ð´Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Â«ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ðµ âÐÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñâ Ð½Ð° Ð Ð Ð¸ Ð² Ð¿Ð¾Ð¼ÐµÑÐµÐ½Ð¸ÑÑ, Ð¾ÑÐ½Ð°ÑÐµÐ½Ð½ÑÑ ÐÐ­ÐÐ, Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸ÑÑ, Ð¿Ð¾Ð´Ð²ÐµÐ´Ð¾Ð¼ÑÑÐ²ÐµÐ½Ð½ÑÑ ÐÐ¸Ð½Ð¾Ð±ÑÐ½Ð°ÑÐºÐ¸ Ð Ð¾ÑÑÐ¸Ð¸Â» Ð°Ð´ÑÐµÑÐ¾Ð²Ð°Ð½Ð¾ ÐºÐ°Ðº ÑÑÑÐ´ÐµÐ½ÑÐ°Ð¼ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Â«Ð¢ÐµÑÐ½Ð¾ÑÑÐµÑÐ½Ð°Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑÂ», ÑÐ°Ðº Ð¸ ÑÑÐºÐ¾Ð²Ð¾Ð´Ð¸ÑÐµÐ»ÑÐ¼ Ð°ÑÐ´Ð¸ÑÐ¾ÑÑÐºÐ¸Ñ Ð³ÑÑÐ¿Ð¿, ÑÐ»ÐµÐ½Ð°Ð¼ ÐºÐ¾Ð¼Ð°Ð½Ð´Ñ Ð²Ð½ÑÑÑÐµÐ½Ð½Ð¸Ñ Ð°ÑÐ´Ð¸ÑÐ¾ÑÐ¾Ð² Ð¸ ÑÑÐºÐ¾Ð²Ð¾Ð´Ð¸ÑÐµÐ»ÑÐ¼ ÑÑÑÑÐºÑÑÑÐ½ÑÑ Ð¿Ð¾Ð´ÑÐ°Ð·Ð´ÐµÐ»ÐµÐ½Ð¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑÐ¾Ð² Ð¸ Ð¸Ð½ÑÑÐ¸ÑÑÑÐ¾Ð², Ð¾ÑÐ²ÐµÑÑÑÐ²ÐµÐ½Ð½ÑÑ Ð·Ð° ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ñ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð¸Ñ Ð²Ð½ÑÑÑÐµÐ½Ð½ÐµÐ³Ð¾ Ð°ÑÐ´Ð¸ÑÐ° Ð¾ÑÑÐ°Ð½Ñ ÑÑÑÐ´Ð°. ÐÐ°ÑÑÐ½Ð°Ñ ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÑ 2.10.3 Â«ÐÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ ÑÑÑÐ´Ð°Â».
Enhancement of electronic anomalies in iron-substituted La_2-x_Sr_x_Cu_1-y_Fe_y_O_4_ around x=0.22
Creators: name: Adachi, T.
name: Sato, H.
name: Fujita, M.
name: Yamada, K.
name: Koike, Y.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We have measured the temperature dependences of Rho and Chi for Fe-substituted La_2-x_Sr_x_Cu_1-y_Fe_y_O_4_ in the overdoped regime, in order to investigate Fe-substitution effects on electronic properties around x=0.22. From the Rho measurements, it has been found around x=0.22 that the values of Rho are large at room temperature and that Rho exhibits a pronounced upturn at low temperatures. Moreover, from the Rho and Chi measurements, it has been found that T_c_ is anomalously depressed around x=0.22. These results indicate that the electronic anomalies around x=0.22 are enhanced by Fe substitution, which might be related to the development of stripe correlations by Fe substitution.
description: 7 pages, 3 figures
Two white dwarfs with oxygen-rich atmospheres
Creators: name: Gaensicke, B. T.
name: Koester, D.
name: Girven, J.
name: Marsh, T. R.
name: Steeghs, D.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Stars with masses in the range 7-10Msun end their lives either as massive white dwarfs or weak type II supernovae, and there are only limited observational constraints of either channel. Here we report the detection of two white dwarfs with large photospheric oxygen abundances, implying that they are bare oxygen-neon cores and that they may have descended from the most massive progenitors that avoid core-collapse.
description: Accepted by Science, first published online on November 12, 2009 in Science Express. Main Science article and Supporting Online Material combined in one file
Additional file 6 of The effect of the head-up position on cardiopulmonary resuscitation: a systematic review and meta-analysis
Creators: name: Huang, Cheng-Chieh
name: Chen, Kuan-Chih
name: Lin, Zih-Yang
name: Chou, Yu-Hsuan
name: Chen, Wen-Liang
name: Lee, Tsung-Han
name: Lin, Kun-Te
name: Hsieh, Pei-You
name: Chen, Cheng Hsu
name: Chou, Chu-Chung
name: Lin, Yan-Ren
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 6. “Priming” versus “no priming”.
Vitamin D induces NO-dependent proliferation and migration in HUVEC
Creators: name: Pittarella, Pamela
name: Uberti, Francesca
name: Rizzi, Manuela
name: Molinari, Claudio
name: Renò, Filippo
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015
Subjects: Cell migration; Endothelial cell; Matrix metalloproteinase-2; Nitric oxide; Vitamin D

description: Recently, Vitamin D (Vit. D) has gained importance in cellular functions of a wide range of extraskeletal organs and target tissues, other than bone. In particular, Vit. D has displayed important beneficial effects in the cardiovascular system (1). Although little is known about the mechanism by which this response is exerted, a Vit. D-induced eNOS-dependent nitric oxide (NO) production in endothelial cells (EC) has been reported (2). The aim of this study was to evaluate whether Vit. D administration could affect human EC proliferation and/or migration through NO production. For this purpose, HUVEC (human umbilical vein endothelial cells) were used to evaluate Vit. D effects on cell proliferation and migration in a 3D matrix. Experiments were also performed in the presence of the specific VDR ligand ZK159222 and eNOS inhibitor L-NAME. This study demonstrated that Vit. D can promote both HUVEC proliferation and migration in a 3D matrix. These effects were NO dependent, since HUVEC proliferation and migration were abrogated along with Vit. D induced MMP- 2 expression by inhibiting eNOS activity by L-NAME. These findings support the role of Vit. D in the angiogenic process (3), suggesting new applications for Vit. D in tissue repair and wound healing.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
title: Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¸Ð¼Ð¸ ÑÐµÑÑÑÑÐ°Ð¼Ð¸. Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÐºÐ¾Ð¼Ð¿ÐµÑÐµÐ½ÑÐ¸Ð¹ Ð´Ð¾Ð»Ð¶Ð½Ð¾ÑÑÐ¸. Ð§. 2
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: Ð¡Ð¾ÑÐ¾ÐºÐ¸Ð½Ð°, ÐÐ°ÑÐ¸Ñ
Publisher: name: Ð¡ÐÐ±ÐÐ¢Ð­Ð£
Year: 2014
Subjects: ÐºÐ°Ð´ÑÐ¾Ð²ÑÐ¹ Ð¼ÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½Ñ
ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¸Ðµ ÑÐµÑÑÑÑÑ
ÑÑÐµÐ±Ð½Ð¸ÐºÐ¸ Ð¸ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ñ Ð´Ð»Ñ Ð²ÑÐ·Ð¾Ð²

description: Ð£ÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¾ Ð² ÑÐ¾Ð¾ÑÐ²ÐµÑÑÑÐ²Ð¸Ð¸ Ñ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸ÑÐ¼Ð¸ Ð¤ÐµÐ´ÐµÑÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð³Ð¾ÑÑÐ´Ð°ÑÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ° Ð²ÑÑÑÐµÐ³Ð¾ Ð¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ 38.04.02 Â«ÐÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½ÑÂ» (ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ñ Â«ÐÐ°Ð³Ð¸ÑÑÑÂ»), Ð¿ÑÐ¾ÑÐ¸Ð»Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Â«ÐÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½Ñ ÑÐµÐ»Ð¾Ð²ÐµÑÐµÑÐºÐ¸Ñ ÑÐµÑÑÑÑÐ¾Ð²Â». Ð Ð°ÑÑÐ¼Ð°ÑÑÐ¸Ð²Ð°ÑÑÑÑ Ð¼ÐµÑÐ¾Ð´Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¸ Ð½Ð°ÑÑÐ½Ð¾-Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð°ÑÐ¿ÐµÐºÑÑ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ ÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¼Ð¾Ð´ÐµÐ»Ð¸ ÐºÐ¾Ð¼Ð¿ÐµÑÐµÐ½ÑÐ¸Ð¹ Ð¸ ÑÐµÐ³Ð»Ð°Ð¼ÐµÐ½ÑÐ¾Ð², Ð¸ÑÐ¿Ð¾Ð»ÑÐ·ÑÐµÐ¼ÑÑ Ð´Ð»Ñ ÐµÐµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ¸. ÐÐ° ÐºÐ¾Ð½ÐºÑÐµÑÐ½ÑÑ Ð¿ÑÐ¸Ð¼ÐµÑÐ°Ñ Ð¾ÑÑÐ°Ð±Ð°ÑÑÐ²Ð°ÐµÑÑÑ ÑÐ¾Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÐ¹ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ð¹ Ð¸Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸. Ð£ÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð², Ð°ÑÐ¿Ð¸ÑÐ°Ð½ÑÐ¾Ð², ÑÐ»ÑÑÐ°ÑÐµÐ»ÐµÐ¹ Ð²ÑÑÑÐ¸Ñ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ñ ÑÐºÐ¾Ð» Ð¸ Ð¸Ð½ÑÑ ÑÑÐµÐ±Ð½ÑÑ Ð·Ð°Ð²ÐµÐ´ÐµÐ½Ð¸Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð¸ Ð¿ÐµÑÐµÐ¿Ð¾Ð´Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ ÐºÐ°Ð´ÑÐ¾Ð², Ð° ÑÐ°ÐºÐ¶Ðµ Ð² Ð¿Ð¾Ð¼Ð¾ÑÑ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ð¼ ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ°Ð¼, Ð¿ÑÐ¾ÑÐ²Ð»ÑÑÑÐ¸Ð¼ Ð¸Ð½ÑÐµÑÐµÑ Ðº Ð¸Ð½Ð½Ð¾Ð²Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐ¼ Ð¿ÑÐ¾ÐµÐºÑÐ°Ð¼ Ð² Ð¾Ð±Ð»Ð°ÑÑÐ¸ HR-Ð¼ÐµÐ½ÐµÐ´Ð¶Ð¼ÐµÐ½ÑÐ°.
Hadronic spectra in AdS / QCD correspondence
Creators: name: Vega, Alfredo
name: Schmidt, Ivan
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present an holographical soft wall model which is able to reproduce Regge spectra for hadrons with an arbitrary number of constituents. The model includes the anomalous dimension of operators that create hadrons, together with a dilaton, whose form is suggested by Einstein`s equations and the AdS metric
description: 4 pages, 2 figures, to appear in the Proceedings of the VIII Latin American Symposium on Nuclear Physics and Applications, Santiago, Chile, 15-19 December 2009. Talk presented by A. V
title: Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´ÐµÑÐ°Ð»Ð¸ "ÐÑÐ¾Ð½ÑÑÐµÐ¹Ð½"
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¸ÑÐµÐ², ÐÐ³Ð¾ÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ
ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ñ
Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½Ñ
ÑÐ°ÑÑÐµÑ
ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐµÐ·Ð°Ð½Ð¸Ñ
Ð½Ð¾ÑÐ¼Ð° Ð²ÑÐµÐ¼ÐµÐ½Ð¸
Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ
Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ
Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ðµ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð¾
Ð¼ÐµÑÑÐ¸Ðº
ÐºÑÐ¾Ð½ÑÑÐµÐ¹Ð½

description: Ð Ð¿ÐµÑÐ²Ð¾Ð¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ° Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐ½Ð¾ÑÑÐ¸ Ð¾Ð±ÑÐ°Ð±Ð°ÑÑÐ²Ð°ÐµÐ¼Ð¾Ð¹ Ð´ÐµÑÐ°Ð»Ð¸ Â«ÐÐ°Ð»-ÑÐµÑÑÐµÑÐ½ÑÂ», Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð° ÐºÐ¾ÑÑÐµÐºÑÐ¸ÑÐ¾Ð²ÐºÐ° ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ñ ÑÑÐµÐ±Ð¾Ð²Ð°Ð½Ð¸Ð¹ Ðº Ð´ÐµÑÐ°Ð»Ð¸, Ð²ÑÑÐ²Ð»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ Ð¸ Ð²ÑÐ¿Ð¾Ð¼Ð¾Ð³Ð°ÑÐµÐ»ÑÐ½ÑÐµ Ð±Ð°Ð·Ñ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½ ÑÐ¸Ð¿ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²Ð°. Ð ÐºÐ°ÑÐµÑÑÐ²Ðµ Ð°Ð½Ð°Ð»Ð¾Ð³Ð° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ° Ð²Ð·ÑÑ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ð´ÐµÑÐ°Ð»Ð¸ ÑÐ¸Ð¿Ð° Â«Ð²Ð°Ð»Â» Ñ ÑÑÐ°Ð¼Ð¿Ð¾Ð²Ð°Ð½Ð½ÑÐ¹ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¾Ð¹ Ð¸ ÑÐºÐ¾ÑÑÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½ Ð¿Ð¾Ð´ Ð´Ð°Ð½Ð½ÑÑ Ð´ÐµÑÐ°Ð»Ñ. Ð Ð¿ÑÐ¾ÑÐµÑÑÐµ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¹ Ð¸ Ð¿ÐµÑÐµÑÐ¾Ð´Ð¾Ð² Ð²ÑÐ±ÑÐ°Ð½Ñ ÑÑÐµÐ´ÑÑÐ²Ð° Ð¾ÑÐ½Ð°ÑÐµÐ½Ð¸Ñ, ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½Ñ ÑÐµÐ¶Ð¸Ð¼Ñ ÑÐµÐ·Ð°Ð½Ð¸Ñ Ð¸ Ð½Ð¾ÑÐ¼Ñ Ð²ÑÐµÐ¼ÐµÐ½Ð¸, Ð²ÑÐ±ÑÐ°Ð½ Ð¼ÐµÑÐ¾Ð´ ÑÐ°Ð·Ð¼ÐµÑÐ½Ð¾Ð¹ Ð½Ð°Ð»Ð°Ð´ÐºÐ¸ Ð¸ ÑÐ°ÑÑÑÐ¸ÑÐ°Ð½ Ð½Ð°Ð»Ð°Ð´Ð¾ÑÐ½ÑÐ¹ ÑÐ°Ð·Ð¼ÐµÑ, ÑÑÐ¾ÑÐ¼Ð¸ÑÐ¾Ð²Ð°Ð½ ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð¹ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°ÑÐ¸Ð¸. ÐÐ¾ Ð²ÑÐ¾ÑÐ¾Ð¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ ÑÐ°Ð±Ð¾ÑÑ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½ ÑÐ°ÑÑÐµÑ ÐºÐ¾Ð½ÑÑÑÑÐºÑÐ¸Ð²Ð½ÑÑ Ð¿Ð°ÑÐ°Ð¼ÐµÑÑÐ¾Ð² ÑÐµÐ¶ÑÑÐ¸Ñ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² Ð´Ð»Ñ Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸ Ð½Ð° Ð¾ÑÐ´ÐµÐ»ÑÐ½ÑÑ Ð¾Ð¿ÐµÑÐ°ÑÐ¸ÑÑ: ÑÐ°ÑÐ¾Ð½Ð½ÑÐ¹ Ð´Ð¸ÑÐºÐ¾Ð²ÑÐ¹ ÑÐµÐ·ÐµÑ, ÐºÐ¾Ð¼Ð¿Ð»ÐµÐºÑ Ð¼ÐµÑÑÐ¸ÐºÐ¾Ð² Ð¸ ÑÐµÑÐ²ÑÑÐ½Ð°Ñ ÑÑÐµÐ·Ð° Ð´Ð»Ñ Ð½Ð°ÑÐµÐ·Ð°Ð½Ð¸Ñ ÑÐ¸Ð»Ð¸Ð½Ð´ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð·ÑÐ±ÑÐ°ÑÑÑ ÐºÐ¾Ð»ÐµÑ. Ð ÑÑÐµÑÑÐµÐ¼ ÑÐ°Ð·Ð´ÐµÐ»Ðµ Ð¿ÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð°Ð²ÑÐ¾Ð¼Ð°ÑÐ¸Ð·Ð°ÑÐ¸Ñ Ð¾Ð´Ð½Ð¾Ð³Ð¾ Ð¿ÐµÑÐµÑÐ¾Ð´Ð° Ð¾Ð±ÑÐ°Ð±Ð¾ÑÐºÐ¸ Ð·Ð°Ð³Ð¾ÑÐ¾Ð²ÐºÐ¸. ÐÑÐ±ÑÐ°Ð½Ñ Ð¸ Ð¿ÑÐ¾Ð°Ð½Ð°Ð»Ð¸Ð·Ð¸ÑÐ¾Ð²Ð°Ð½Ñ Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½ÑÐµ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð°, Ð¾ÑÑÐµÐºÐ°ÑÐµÐ»Ð¸. ÐÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½ ÑÐ°ÑÑÐµÑ Ð½ÐµÐºÐ¾ÑÐ¾ÑÑÑ ÑÐ»ÐµÐ¼ÐµÐ½ÑÐ¾Ð² Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð° Ð¸ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð° ÑÐ¸ÐºÐ»Ð¾Ð³ÑÐ°Ð¼Ð¼Ð° ÑÐ°Ð±Ð¾ÑÑ Ð·Ð°Ð³ÑÑÐ·Ð¾ÑÐ½Ð¾Ð³Ð¾ ÑÑÑÑÐ¾Ð¹ÑÑÐ²Ð° Ð¸ ÑÑÐ°Ð½ÐºÐ°.
Velocity Characteristics of Evaporated Plasma Using Hinode/EIS
Creators: name: Milligan, Ryan O.
name: Dennis, Brian R.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: This paper presents a detailed study of chromospheric evaporation using the EUV Imaging Spectrometer (EIS) onboard Hinode in conjunction with HXR observations from RHESSI. The advanced capabilities of EIS were used to measure Doppler shifts in 15 emission lines covering the temperature range T=0.05-16 MK during the impulsive phase of a C-class flare on 2007 December 14. Blueshifts indicative of the evaporated material were observed in six emission lines from Fe XIV-XXIV (2-16 MK). Upflow velocity (v_up) was found to scale with temperature as v_up (km s^-1)~8-18 T (MK). Although the hottest emission lines, Fe XXIII and Fe XXIV, exhibited upflows of >200 km s^-1, their line profiles were found to be dominated by a stationary component in contrast to the predictions of the standard flare model. Emission from O VI-Fe XIII lines (0.5-1.5 MK) was found to be redshifted by v_down (km s^-1)~60-17 T (MK) and was interpreted as the downward-moving `plug' characteristic of explosive evaporation. These downflows occur at temperatures significantly higher than previously expected. Both upflows and downflows were spatially and temporally correlated with HXR emission observed by RHESSI that provided the properties of the electron beam deemed to be the driver of the evaporation. The energy flux of the electron beam was found to be >5x10^10 ergs cm^-2 s^-1 consistent with the value required to drive explosive chromospheric evaporation from hydrodynamic simulations.
description: 9 pages, 7 figures, 1 table, ApJ (Accepted)
title: ÐÐ»Ð³Ð¾ÑÐ¸ÑÐ¼Ñ Ð¸Ð´ÐµÐ½ÑÐ¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¸ Ð³ÐµÐ¾Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¾Ð±ÑÐµÐºÑÐ¾Ð² Ð² ÐºÐ°ÑÑÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¾Ð¼ Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ð¸
title: Ð¼Ð°Ð³Ð¸ÑÑÐµÑÑÐºÐ°Ñ Ð´Ð¸ÑÑÐµÑÑÐ°ÑÐ¸Ñ
titleType: Subtitle
Creators: name: ÐÐ²Ð°Ð½Ð¾Ð²Ð°, ÐÐ»Ð¸Ð·Ð°Ð²ÐµÑÐ°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÐÐµÐ¾Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸ÐºÐ°
ÐÐ°ÑÑÐ¾Ð³ÑÐ°ÑÐ¸Ñ
ÐÐ»Ð³Ð¾ÑÐ¸ÑÐ¼Ñ
ÐÐ½ÑÐµÑÐ½ÐµÑ
Ð³ÐµÐ¾Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÐµ ÑÐ¸ÑÑÐµÐ¼Ñ
Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÐµ ÐºÐ°ÑÑÑ
googlemapsapi
yandexmapapi

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÑÑÑÑ ÐºÐ°ÑÑÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ. Ð¦ÐµÐ»Ñ ÑÐ°Ð±Ð¾ÑÑ - Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ð¹ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÐ¾Ð² ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÐºÐ°ÑÑÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ñ Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ð¹ Ð¸ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½Ð¾Ð¹ ÐºÐ°ÑÑÑ, Ð¿Ð¾Ð·Ð²Ð¾Ð»ÑÑÑÐµÐ¹ ÑÐ°Ð±Ð¾ÑÐ°ÑÑ Ñ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð»ÑÐ½ÑÐ¼ Ð½Ð°Ð±Ð¾ÑÐ¾Ð¼ ÑÐ»Ð¾ÐµÐ². Ð Ð¿ÑÐ¾ÑÐµÑÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð° Ð¾Ð±ÑÐ°Ñ ÑÑÐµÐ¼Ð° Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ Ð¼Ð½Ð¾Ð³Ð¾ÑÐ»Ð¾Ð¹Ð½ÑÑ Ð¾Ð½Ð»Ð°Ð¹Ð½-ÐºÐ°ÑÑ Ð¸ Ð¸Ð½ÑÑÑÑÐ¼ÐµÐ½ÑÑ Ð´Ð»Ñ ÐµÑ ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¸ Ð¾ÑÐ¾Ð±ÑÐ°Ð¶ÐµÐ½Ð¸Ñ Ð² Ð²ÐµÐ±-Ð±ÑÐ°ÑÐ·ÐµÑÐµ. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ° ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ Ð¸Ð½ÑÐµÑÐ°ÐºÑÐ¸Ð²Ð½ÑÑ Ð¼Ð½Ð¾Ð³Ð¾ÑÐ»Ð¾Ð¹Ð½ÑÑ ÐºÐ°ÑÑ Ð¸ ÑÐ¾Ð·Ð´Ð°Ð½Ð¾ Ð²ÐµÐ±-Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ, Ð¾Ð±Ð»ÐµÐ³ÑÐ°ÑÑÐµÐµ ÑÐ°Ð±Ð¾ÑÑ Ñ ÐºÐ°ÑÑÐ¾Ð³ÑÐ°ÑÐ¸ÑÐµÑÐºÐ¸Ð¼Ð¸ Ð´Ð°Ð½Ð½ÑÐ¼Ð¸.
Additional file 7 of The effect of the head-up position on cardiopulmonary resuscitation: a systematic review and meta-analysis
Creators: name: Huang, Cheng-Chieh
name: Chen, Kuan-Chih
name: Lin, Zih-Yang
name: Chou, Yu-Hsuan
name: Chen, Wen-Liang
name: Lee, Tsung-Han
name: Lin, Kun-Te
name: Hsieh, Pei-You
name: Chen, Cheng Hsu
name: Chou, Chu-Chung
name: Lin, Yan-Ren
Publisher: name: figshare
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 7. “Head/chest up only” position versus “reverse-Trendelenburg” position
Nonylphenol affects activity of human reproductive cells
Creators: name: Di Lorenzo, Mariana
name: Forte, Maurizio
name: Lucariello, Angela
name: Iachetta, Giuseppina
name: Laforgia, Vincenza
name: De Falco, Maria
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Nonylphenol (NP) is an industrial compound belonging to Endocrine Disrupting Chemicals (EDCs) with xenoestrogenic activity abundantly present in the environment. Its xenoestrogenic activity was demonstrated both in vitro and in vivo. Estrogens play an important role in development and growth of human endometrium and prostate. Since NP mimics endogenous estrogens, it could have a negative influence on normal physiology of both organs. In this study we examined the effects of NP and 17-β-estradiol (E2) on human prostate adenocarcinoma epithelial cell line (LNCaP) and endometrial adenocarcinoma cell line Ishikawa. Firstly, we performed a MTT assay in order to see cell proliferation. We found that both NP and E2 stimulated prostate and endometrial cell proliferation but in different manner. In fact, on human prostate cells NP induced a non-monotonic increase of cell proliferation whereas on endometrial cells its effect was dose-dependent. Secondly, we studied expression and localization of estrogen receptor alpha (ERα) in both LNCaP and Ishikawa cells. Immunofluorescence and western blot analyses revealed that both NP and E2 induced cytoplasm-nucleus translocation of ERα even if E2 was able to induce an early nuclear translocation respect to NP. Finally through qPCR analysis we studied changing in gene expression of genes involved in proliferation pathways. We observed that in prostate cells NP and E2 induced upregulation of cyclin D1, ki-67, cytochine IL-8 and IL-1β together with a downregulation of cyclin E. On the contrary, in human endometrial cells gene upregulation was present only after E2 treatment whereas NP seem have no effects on these specific gene targets. These results showed that NP has estrogenic activity on human reproductive cells both in male and female system, but probably it may also interfere with other molecular pathways to induce a deregulation of normal cell physiology as seen in human endometrial cells.
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
A Hypergraph Dictatorship Test with Perfect Completeness
Creators: name: Chen, Victor
Publisher: name: arXiv
Year: 2008
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: A hypergraph dictatorship test is first introduced by Samorodnitsky and Trevisan and serves as a key component in their unique games based $\PCP$ construction. Such a test has oracle access to a collection of functions and determines whether all the functions are the same dictatorship, or all their low degree influences are $o(1).$ Their test makes $q\geq3$ queries and has amortized query complexity $1+O(\frac{\log q}{q})$ but has an inherent loss of perfect completeness. In this paper we give an adaptive hypergraph dictatorship test that achieves both perfect completeness and amortized query complexity $1+O(\frac{\log q}{q})$.
description: Some minor corrections
Effects of peat and sawdust mulches and their leachates on the growth and certain metabolic reactions of the highbush blueberry : (Vaccinium corymbosum L. var Coville)
Creators: name: Osborne, James Robert
Publisher: name: University of British Columbia
Year: 2011

description: Greenhouse, field and laboratory experiments were conducted to ascertain some growth and metabolic responses of the Coville blueberry variety, to sawdust and peat mulches, and the leachates of these mulches. From the greenhouse experiments it would appear that in some manner the mulches in question increased the metabolic activities of the plants. The increased activity was reflected by increased growth of the mulched plants, a higher ash content and a higher total nitrogen content of the leaves. A greater concentration of free amino acids occurred in the unmulched plants than in the mulched ones. This indicates that the nitrogen metabolic activities were hastened by the mulching.
Biases in the polarization position angles in the NVSS point source catalogue
Creators: name: Battye, R. A.
name: Browne, I. W. A.
name: Jackson, N.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We have examined the statistics of the polarization position angles determined for point sources in the NRAO-VLA sky survey (NVSS) and find that there is a statistically significant bias toward angles which are multiples of 45 degrees. The formal probability that the polarization angles are drawn from a uniform distribution is exponentially small. When the sample of those NVSS sources with polarizations detected with a signal to noise $\geq$3 is split either around the median polarized flux density or the median fractional polarization, the effect appears to be stronger for the more highly polarized sources. Regions containing strong sources and regions at low galactic latitudes are not responsible for the non-uniform distribution of position angles. We identify CLEAN bias as the probable cause of the dominant effect, coupled with small multiplicative and additive offsets on each of the Stokes parameters. Our findings have implications for the extraction of science, such as information concerning galactic magnetic fields, from large scale polarization surveys.
title: Ð£ÑÐµÑ Ð¸ Ð°ÑÐ´Ð¸Ñ ÑÐ°ÑÑÐµÑÐ¾Ð² Ñ Ð¿Ð¾ÐºÑÐ¿Ð°ÑÐµÐ»ÑÐ¼Ð¸ Ð¸ Ð·Ð°ÐºÐ°Ð·ÑÐ¸ÐºÐ°Ð¼Ð¸ Ð² ÑÐ¸ÑÑÐµÐ¼Ðµ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾Ð´Ð°Ð¶Ð°Ð¼Ð¸
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ³Ð¾ÑÐ¾Ð², ÐÐ»ÑÑ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: Ð¿Ð¾ÐºÑÐ¿Ð°ÑÐµÐ»Ð¸
ÐºÐ»Ð¸ÐµÐ½ÑÑ
Ð±ÑÑ Ð³Ð°Ð»ÑÐµÑÑÐºÐ¸Ð¹ ÑÑÐµÑ
Ð°ÑÐ´Ð¸Ñ

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ ÑÑÐµÑ Ð¸ Ð°ÑÐ´Ð¸Ñ ÑÐ°ÑÑÐµÑÐ¾Ð² Ñ Ð¿Ð¾ÐºÑÐ¿Ð°ÑÐµÐ»ÑÐ¼Ð¸ Ð¸ Ð·Ð°ÐºÐ°Ð·ÑÐ¸ÐºÐ°Ð¼Ð¸ Ð² ÑÐ¸ÑÑÐµÐ¼Ðµ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð¿ÑÐ¾Ð´Ð°Ð¶Ð°Ð¼Ð¸. Ð¦ÐµÐ»ÑÑ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÐµÑÑÑ Ð¸Ð·ÑÑÐµÐ½Ð¸Ðµ Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¸ Ð¿ÑÐ°ÐºÑÐ¸ÑÐµÑÐºÐ¸Ðµ ÐºÑÐ¸ÑÐµÑÐ¸Ð¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÐ¸ÑÑÐµÐ¼Ñ ÑÑÐµÑÐ° Ð¸ Ð°ÑÐ´Ð¸ÑÐ° ÑÐ°ÑÑÐµÑÐ¾Ð² Ñ Ð·Ð°ÐºÐ°Ð·ÑÐ¸ÐºÐ°Ð¼Ð¸ Ð¸ Ð¿Ð¾ÐºÑÐ¿Ð°ÑÐµÐ»ÑÐ¼Ð¸. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð´ÐµÑÐ°Ð»ÑÐ½Ð¾ Ð¾Ð·Ð½Ð°ÐºÐ¾Ð¼Ð¸Ð»ÑÑ Ñ ÑÑÐµÑÐ¾Ð¼ ÑÐ°ÑÑÐµÑÐ¾Ð² Ð¿Ð¾ÐºÑÐ¿Ð°ÑÐµÐ»ÐµÐ¹ Ð¸ Ð·Ð°ÐºÐ°Ð·ÑÐ¸ÐºÐ¾Ð² Ð·Ð° Ð²ÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð½ÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð¸ Ð¾ÐºÐ°Ð·Ð°Ð½Ð½ÑÐµ ÑÑÐ»ÑÐ³Ð¸. ÐÐ·ÑÑÐµÐ½Ñ Ð·Ð°ÐºÐ¾Ð½Ð¾Ð´Ð°ÑÐµÐ»ÑÐ½Ð¾ - Ð½Ð¾ÑÐ¼Ð°ÑÐ¸Ð²Ð½ÑÐµ Ð¾ÑÐ½Ð¾Ð²Ñ ÑÑÐµÑÐ° ÑÐ°ÑÑÐµÑÐ¾Ð², Ð¾Ð±Ð¾Ð·Ð½Ð°ÑÐµÐ½Ñ ÑÑÑÐ½Ð¾ÑÑÑ ÑÐ°ÑÑÐµÑÐ¾Ð², Ð²Ð¸Ð´Ñ Ð¸ ÑÐ¾ÑÐ¼Ñ ÑÐ°ÑÑÐµÑÐ¾Ð², ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð¾ Ð´Ð¾ÐºÑÐ¼ÐµÐ½ÑÐ°Ð»ÑÐ½Ð¾Ðµ Ð¾ÑÐ¾ÑÐ¼Ð»ÐµÐ½Ð¸Ðµ ÑÐ°ÑÑÐµÑÐ¾Ð², Ð¸ ÑÐ°ÑÐºÑÑÑÐ° Ð¸Ð½ÑÐ¾ÑÐ¼Ð°ÑÐ¸Ñ Ð¾Ð± ÑÑÐµÑÐµ ÑÐ°ÑÑÐµÑÐ¾Ð² Ñ Ð·Ð°ÐºÐ°Ð·ÑÐ¸ÐºÐ°Ð¼Ð¸ Ð¸ Ð¿Ð¾ÐºÑÐ¿Ð°ÑÐµÐ»ÑÐ¼Ð¸ Ð² Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸.
title: Standing Committee on the Law of Trademarks, Industrial Designs and Geographical Indications :
title: Report adopted by the Special Session of the Standing Committee.
titleType: Subtitle
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 0

description: In accordance with the decision of the WIPO General Assembly at its meeting in September 2001 (document WO/GA/27/8) that the Standing Committee on the Law of Trademarks, Industrial Designs and Geographical Indications (SCT) hold two special sessions on the Report of the Second WIPO Internet Domain Name Process (the “Special Sessions”), the second such Special Session was held in Geneva from May 21 to May 24, 2002.
Dynamically broken symmetry in periodically gated quantum dots: Charge accumulation and dc-current
Creators: name: Kwapinski, T.
name: Kohler, S.
name: Hanggi, P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Time-dependent electron transport through a quantum dot and double quantum dot systems in the presence of polychromatic external periodic quantum dot energy-level modulations is studied within the time evolution operator method for a tight-binding Hamiltonian. Analytical relations for the dc-current flowing through the system and the charge accumulated on a quantum dot are obtained for the zero-temperature limit. It is shown that in the presence of periodic perturbations the sideband peaks of the transmission are related to combination frequencies of the applied modulations. For a double quantum dot system under the influence of polychromatic perturbations the quantum pump effect is studied in the absence of source-drain and static bias voltages. In the presence of spatial symmetry the charge is pumped through the system due to broken generalized parity symmetry.
description: 10 pages, 7 figures, to appear in UJP (Ukr.J.Phys.)
Triclosan and estradiol effects on human prostate cells
Creators: name: Di Lorenzo, Mariana
name: Lucariello, Angela
name: Iachetta, Giuseppina
name: Laforgia, Vincenza
name: De Falco, Maria
name: De Luca, Antonio
Publisher: name: Italian Journal of Anatomy and Embryology
Year: 2015

description: Xenoestrogens are estrogen-mimicking compounds that are commonly found in personal care products and pesticides. The activity of xenoestrogens in the human body involves interference with estrogen receptor binding. Triclosan (TCS), a lesserknown xenoestrogen, is a broad-spectrum antibacterial commonly used in cosmetics, toothpastes, soap and other consumer products. The widespread use of TCS and its detection in human breast milk, urine and serum have raised concerns regarding its association with various health outcomes. Recent evidence suggests that TCS may play a role in cancer development, perhaps through its estrogenicity. In the present work we have studied the effects of TCS and Estrogen (E2) on human prostate adenocarcinoma epithelial cells (LNCaP) in order to highlight estrogen and xenoestrogen influence on human prostate. Although androgens are the most important hormones in the normal development of the male reproductive system, more recently, it has been suggested a central role for estrogen in male reproductive system and it has been hypothesized that high level of estrogens may disturb the endocrine control of the male reproductive capability. We examined the effects of TCS and E2 on the proliferation of the LNCaP through MTT assay. They were both able to increase cell proliferation at concentration of 10-8 M after 24h of treatment. In order to study estrogen receptor (ER) involvement, we evaluated the cellular localization and expression of ERs with immunofluorescence and western blot techniques after treatment with TCS and E2. Finally, through Real Time PCR analysis we have investigated gene expression of several molecular targets of estrogen pathway. We have observed that treatment with TCS and E2 induced an upregulation of Ki-67, cyclin D1 and cyclin E. We have also observed an upregulation of proinflammatory cytochines Il-1β after TCS and E2 treatment. These results confirm the estrogenic activity of TCS and suggest that estrogen and xenoestrogens may interfere with molecular pathways of prostate physiology
description: Italian Journal of Anatomy and Embryology, Vol. 120, No. 1 (Supplement) 2015
title: ÐÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ Ñ Ð½Ð°ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ ÐºÑÑ Ð½ÐµÐ¹
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ¾ÑÐºÐ²Ð¸Ð½Ð°, ÐÐ»ÐµÐ½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ðµ Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ
Ð¾ÑÐµÐ½ÐºÐ° ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ñ Ð¾Ð·ÑÐ¹ÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð°
ÑÐµÑÑÐ¾ÑÐ°Ð½Ñ Ð½Ð°ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ ÐºÑÑ Ð½Ð¸
Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ Ð´Ð»Ñ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð°

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ Ð²ÑÑÑÑÐ¿Ð°ÐµÑ ÑÐµÑÑÐ¾ÑÐ°Ð½ Ð°ÑÐ¼ÑÐ½ÑÐºÐ¾Ð¹ ÐºÑÑÐ½Ð¸ Â«ÐÐ¼ÑÐ¾ÑÂ».
Ð¦ÐµÐ»Ñ Ð²ÑÐ¿ÑÑÐºÐ½Ð¾Ð¹ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÑ: ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¹ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÐ°Ð±Ð¾ÑÑ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð°ÑÐ¼ÑÐ½ÑÐºÐ¾Ð¹ ÐºÑÑÐ½Ð¸ Â«ÐÐ¼ÑÐ¾ÑÂ».
Ð Ð°Ð±Ð¾ÑÐ° Ð²ÐºÐ»ÑÑÐ°ÐµÑ Ð²ÑÑÐ²Ð»ÐµÐ½Ð¸Ðµ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐµÐ¹ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð½Ð°ÑÐ¸Ð¾Ð½Ð°Ð»ÑÐ½Ð¾Ð¹ ÐºÑÑÐ½Ð¸, Ð¸Ð·ÑÑÐµÐ½Ð¸Ðµ Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÑÑÐºÑÑÑÑ Ð ÐµÑÑÐ¾ÑÐ°Ð½Ð° Â«ÐÐ¼ÑÐ¾ÑÂ», Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²ÑÐ¹ Ð¸ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Â«ÐÐ¼ÑÐ¾ÑÂ», Ð²Ð½ÐµÐ´ÑÐµÐ½Ð¸Ðµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð¿Ð¾ ÑÐ»ÑÑÑÐµÐ½Ð¸Ñ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð¸ Ð¾ÑÐµÐ½ÐºÑ Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸.
 Ð ÑÐ°Ð¼ÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÑ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ Â«ÐÐ¼ÑÐ¾ÑÂ», Ð° ÑÐ°ÐºÐ¶Ðµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð½Ð°Ð¿ÑÐ°Ð²Ð»ÐµÐ½Ð½ÑÐµ Ð½Ð° ÑÐ»ÑÑÑÐµÐ½Ð¸Ðµ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ¾Ð² ÑÐ¾Ð·ÑÐ¹ÑÑÐ²ÐµÐ½Ð½Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð°, ÑÐ²ÐµÐ»Ð¸ÑÐµÐ½Ð¸Ðµ ÐºÐ¾Ð»Ð¸ÑÐµÑÑÐ²Ð° Ð¿Ð¾ÑÐµÑÐ¸ÑÐµÐ»ÐµÐ¹ Ð¸ Ð¿Ð¾Ð²ÑÑÐµÐ½Ð¸Ðµ Ð»Ð¾ÑÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐºÐ»Ð¸ÐµÐ½ÑÐ¾Ð².
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ Ð¿ÑÐ¾ÑÐµÑÑÐ° ÑÐµÐ¼Ð¾Ð½ÑÐ° Ð¿ÑÐ¾Ð´ÑÐ²Ð¾ÑÐ½Ð¾Ð¹ ÐºÐ¾Ð»Ð¾Ð½Ð½Ñ
title: Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½ÑÐ¹ Ð¿ÑÐ¾ÐµÐºÑ
titleType: Subtitle
Creators: name: Ð¤ÑÐ°Ð½ÑÐ¾Ð², Ð¡ÐµÐ¼ÐµÐ½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2016
Subjects: ÑÑÑÐ½Ð°Ñ Ð°ÑÐ³Ð¾Ð½Ð¾Ð´ÑÐ³Ð¾Ð²Ð°Ñ ÑÐ²Ð°ÑÐºÐ°
ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð¿ÑÐ¾ÑÐµÑÑ ÑÐ²Ð°ÑÐºÐ¸ Ð²ÑÑÐ°Ð²ÐºÐ¸
ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ ÐºÐ°ÑÐµÑÑÐ²Ð°
ÑÐ¸ÑÐ°Ð½

description: Ð Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½Ð¾Ð¼ Ð¿ÑÐ¾ÐµÐºÑÐµ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ñ ÑÐµÐ¼Ð¾Ð½ÑÐ° ÑÐ²Ð°ÑÐºÐ¾Ð¹ Ð¿ÑÐ¾Ð´ÑÐ²Ð¾ÑÐ½Ð¾Ð¹ ÐºÐ¾Ð»Ð¾Ð½Ð½Ñ Ð¸Ð· ÑÐ¸ÑÐ°Ð½Ð°. Ð Ð°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ ÑÐ²Ð°ÑÐºÐ¸ ÑÐ¸ÑÐ°Ð½Ð° Ð¸ ÑÐ¸ÑÐ°Ð½Ð¾Ð²ÑÑ ÑÐ¿Ð»Ð°Ð²Ð¾Ð². ÐÑÐ¸Ð½ÑÑ ÑÐµÐ¶Ð¸Ð¼ ÑÑÑÐ½Ð¾Ð¹ Ð°ÑÐ³Ð¾Ð½Ð¾Ð´ÑÐ³Ð¾Ð²Ð¾Ð¹ ÑÐ²Ð°ÑÐºÐ¸ Ð½ÐµÐ¿Ð»Ð°Ð²ÑÑÐ¸Ð¼ÑÑ ÑÐ»ÐµÐºÑÑÐ¾Ð´Ð¾Ð¼, ÑÐ²Ð°ÑÐ¾ÑÐ½Ð¾Ðµ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð¸ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ñ. ÐÑÐ¸Ð²ÐµÐ´ÐµÐ½Ñ Ð¼ÐµÑÐ¾Ð´Ñ Ð·Ð°ÑÐ¸ÑÑ ÑÐ²Ð°ÑÐ½Ð¾Ð³Ð¾ ÑÐ²Ð° Ñ Ð¾Ð±ÑÐ°ÑÐ½Ð¾Ð¹ ÑÑÐ¾ÑÐ¾Ð½Ñ. Ð Ð°ÑÑÑÐ¸ÑÐ°Ð½Ð° ÑÐµÐ±ÐµÑÑÐ¾Ð¸Ð¼Ð¾ÑÑÑ Ð²Ð²Ð°ÑÐºÐ¸ Ð²ÑÑÐ°Ð²ÐºÐ¸ Ð² Ð¾Ð±ÐµÑÐ°Ð¹ÐºÑ Ð¿ÑÐ¾Ð´ÑÐ²Ð¾ÑÐ½Ð¾Ð¹ ÐºÐ¾Ð»Ð¾Ð½Ð½Ñ. ÐÐ¿Ð¸ÑÐ°Ð½Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¾ ÑÐµÑÐ½Ð¸ÐºÐ¸ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð¸ Ð¾ÑÑÐ°Ð½Ðµ ÑÑÑÐ´Ð°.
Diffraction radiation from a screen of finite conductivity
Creators: name: Karlovets, D. V.
name: Potylitsyn, A. P.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Optics (physics.optics)
subject: Classical Physics (physics.class-ph)
subject: FOS: Physical sciences

description: An exact solution has been found for the problem of diffraction radiation appearing when a charged particle moves perpendicularly to a thin finite screen having arbitrary conductivity and frequency dispersion. Expressions describing the Diffraction and Cherenkov emission mechanisms have been obtained for the spectral-angular forward and backward radiation densities.
description: 6 pages, 4 figures