cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Inexact relative smoothness and strong convexity for optimization and variational inequalities by inexact model
Creators: name: Stonyakin, Fedor
name: Gasnikov, Alexander
name: Tyurin, Alexander
name: Pasechnyuk, Dmitry
name: Agafonov, Artem
name: Dvurechensky, Pavel
name: Dvinskikh, Darina
name: Artamonov, Sergei
name: Piskunova, Victorya
Publisher: name: Weierstrass Institute
Year: 2020
Subjects: subject: Convex optimization
subject: composite optimization
subject: proximal method
subject: level-set method
subject: variational inequality
subject: universal method
subject: mirror prox
subject: acceleration
subject: relative smoothness
subject: saddle-point problem
subject: 90C30
subject: 90C25
subject: 68Q25
subject: 65K15

description: In this paper we propose a general algorithmic framework for first-order methods in optimization in a broad sense, including minimization problems, saddle-point problems and variational inequalities. This framework allows to obtain many known methods as a special case, the list including accelerated gradient method, composite optimization methods, level-set methods, Bregman proximal methods. The idea of the framework is based on constructing an inexact model of the main problem component, i.e. objective function in optimization or operator in variational inequalities. Besides reproducing known results, our framework allows to construct new methods, which we illustrate by constructing a universal conditional gradient method and universal method for variational inequalities with composite structure. These method works for smooth and non-smooth problems with optimal complexity without a priori knowledge of the problem smoothness. As a particular case of our general framework, we introduce relative smoothness for operators and propose an algorithm for VIs with such operator. We also generalize our framework for relatively strongly convex objectives and strongly monotone variational inequalities.
Lateralization and coordination: does individual lateralization affect the way fish shoal?
Creators: name: Quattrini, Fausto
Publisher: name: figshare
Year: 2017
Subjects: subject: 60801 Animal Behaviour
subject: FOS: Biological sciences
subject: 60201 Behavioural Ecology

description: Data collected by FQ as part of a mater thesis project supervised by Professor Redouan Bshary and Dr. Dominique G. Roche. Please refer to the manuscript for data collection methods and statistical analyses. Metadata for the .csv data files are included in the ReadMe.txt file. For questions or to notify the authors if any errors are identified in the data, please contact fausto.quattrini@unine.ch This table contains the data recorded during an experiment to examine whether lateralization bias influence grouping behaviour in three species of coral reef fishes.

Abstract:
Brain lateralization is the asymmetrical organisation of brain hemispheres. It generally results in directional biases during behavioural tasks, such as observing prey and predators with a preferred eye. Several advantages might arise from lateralization at the individual level (e.g. increased ability in multitasking). Conversely, it is hypothesized that lateralization at population-level (i.e. when the majority of individuals present the same directional bias) might present some costs, notably, by making individual behaviour predictable for antagonist, such as predators. However, population-level lateralization is often observed in nature. A possible explanation is that uniformity of lateralization might help when member of a population lives in groups and need to be coordinate to increase their fitness. I studied three group living fish species to see whether group cohesion and alignment would be increased when shoal are composed by individuals presenting higher degree of lateralization. All species presented lateralization biases, however only two at population level. In one species the compactness of the group was influenced by length variation within the shoal members. The one species without population-level lateralization presented the higher shoal alignment. However, the degree of lateralization did not influence neither shoal compactness nor alignment.
DTA/19-2015 - The appropriateness and effectiveness of the governance for research funding in Europe
Creators: name: CNR DTA-Dipartimento Terra E Ambiente
Publisher: name: figshare
Year: 2016
Subjects: subject: 160511 Research, Science and Technology Policy
subject: FOS: Political science

description: The process of coordinating/aligning national research programmes at European level is addressed, in particular in relation with competitiveness and growth of territories. Different aspects are involved when Member States cooperate: increasing critical mass, competitiveness, patrol or control, reducing fragmentation and costs. This implies usually the identification of common goals through hierarchically or self-organized decision-making processes. The pros and cons of the identification of “top-down (hierarchically) and bottom-up (self-organized) driven” priorities are described in a period of economic crisis, when funding agencies and performing research organizations can conflict. While Europe is asking to cooperate for joint actions and increase impact in tackling societal challenges, the policy for aligning research could facilitate the agglomeration of skills/excellence and competitiveness in some areas, resulting therefore in geographical unbalances at European level. This paper aims at stimulating a debate on the appropriateness and effectiveness of the governance for research funding in Europe, having in mind that, in a complex system as the European Research Area and its links with industrial competitiveness, it is difficult to evaluate the direct impact of trans-national actions in shaping the evolution of the system itself.
Can the probability of radiation esophagitis be reduced without compromising lung tumor control: A radiobiological modeling study
Creators: name: Hoffmans, Daan
name: Dahele, Max
name: Senan, Suresh
name: Verbakel, Wilko F. A. R.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Can the probability of radiation esophagitis be reduced without compromising lung tumor control: A radiobiological modeling study
title: Understanding the interplay between structure and properties in phase separated copolymer blends prepared by free-radical polymerization
Creators: name: Fage, Julien
Publisher: name: UNSPECIFIED
Year: 2024

description: Polystyrene is the 6th most widely produced and used plastic in the world. Easy to produce and cost effective, it is a transparent and glassy polymer. However, it suffers from its inherent brittleness, which limits its use in certain applications. Enhancement of its toughness has been a focus in the last few decades. The incorporation of rubber particles in a polystyrene matrix allows to increase the toughness of the material but results in an opaque material. The development of block copolymer such as styrene-butadiene-styrene allowed to enhance further the flexibility and toughness of styrenic polymer, whilst keeping their excellent transparency. However, the method needed to prepare such polymers is cost intensive due to the infrastructures and purity of the reagents needed. 
This work focusses on the development of graft copolymer prepared by free-radical polymerization. Free-radical polymerization offers numerical advantages compared to controlled polymerization as it does not require demanding conditions in terms of reagent and environment purity. Poly(butyl acrylate) is used as backbone polymer as it offers significant advantage in terms of UV stability in comparison to polybutadiene. As poly(butyl acrylate) does not have functionalities available for grafting with free-radical polymerization, butyl acrylate needs to be copolymerized with a comonomer. 2 routes have been explored for the synthesis of PBA-g-PS: Route A uses a copolymer backbone made of butyl acrylate and allyl methacrylate or DCPA whilst route B uses a copolymer backbone made of butyl acrylate and glycidyl acrylate or glycidyl methacrylate. In route A, the backbone can be used directly for grafting polymer with styrene, using the unreacted allyl or vinyl functionalities n the backbone. In route B, the backbone undergoes polymer analogous reaction where the glycidyl function is converted to acryloyl reactive groups using acrylic acid. 
The influence of the type of polymerization, emulsion, or solution polymerization is studied for the preparation of the backbone. The graft copolymer blends made of PBA-g-PS and homo-polystyrene are studied in terms of optical and mechanical properties. Transmission electron microscopy is used to determine which type of morphology in the phase separated product is obtained when varying the backbone chemical properties. Finally, the influence of the type of processing, solvent casting or extrusion/injection molding are studied by analyzing the change in mechanical properties as well as the change in morphology.
Automated Program Repair Using Formal Verification Techniques
Creators: name: Frenkel, Hadar
name: Grumberg, Orna
name: Rothenberg, Bat-Chen
name: Sheinvald, Sarai
Publisher: name: CISPA
Year: 2024

description: We focus on two different approaches to automatic program repair, based on formal verification methods. Both repair techniques consider infinite-state C-like programs, and consist of a generate-validate loop, in which potentially repaired programs are repeatedly generated and verified. Both approaches are incremental – partial information gathered in previous verification attempts is used in the next steps. However, the settings of both approaches, including their techniques for finding repairs, are quite distinct. The first approach uses syntactic mutations to repair sequential programs with respect to assertions in the code. It is based on a reduction to the problem of finding unsatisfiable sets of constraints, which is addressed using an interplay between SAT and SMT solvers. A novel notion of must-fault-localization enables efficient pruning of the search space, without losing any potential repair. The second approach uses an Assume-Guarantee (AG) style reasoning in order to verify large programs, composed of two concurrent components. The AG reasoning is based on automata-learning techniques. When verification fails, the procedure repeatedly repairs one of the components, until a correct repair is found. Several different repair methods are considered, trading off precision and convergence to a correct repair.
Biofouling community composition across a range of environmental conditions and geographical locations suitable for floating marine renewable energy generation
Creators: name: Macleod, Adrian K.
name: Stanley, Michele S.
name: Day, John G.
name: Cook, Elizabeth J.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Knowledge of biofouling typical of marine structures is essential for engineers to define appropriate loading criteria in addition to informing other stakeholders about the ecological implications of creating novel artificial environments. There is a lack of information regarding biofouling community composition (including weight and density characteristics) on floating structures associated with future marine renewable energy generation technologies. A network of navigation buoys were identified across a range of geographical areas, environmental conditions (tidal flow speed, temperature and salinity), and deployment durations suitable for future developments. Despite the perceived importance of environmental and temporal factors, geographical location explained the greatest proportion of the observed variation in community composition, emphasising the importance of considering geography when assessing the impact of biofouling on device functioning and associated ecology. The principal taxa associated with variation in biofouling community composition were mussels (Mytilus edulis), which were also important when determining loading criteria.
The appropriateness and effectiveness of the governance for research funding in Europe
Creators: name: CNR DTA-Dipartimento Terra E Ambiente
Publisher: name: figshare
Year: 2016
Subjects: subject: 160511 Research, Science and Technology Policy
subject: FOS: Political science

description: The process of coordinating/aligning national research programmes at European level is addressed, in particular in relation with competitiveness and growth of territories. Different aspects are involved when Member States cooperate: increasing critical mass, competitiveness, patrol or control, reducing fragmentation and costs. This implies usually the identification of common goals through hierarchically or self-organized decision-making processes. The pros and cons of the identification of “top-down (hierarchically) and bottom-up (self-organized) driven” priorities are described in a period of economic crisis, when funding agencies and performing research organizations can conflict. While Europe is asking to cooperate for joint actions and increase impact in tackling societal challenges, the policy for aligning research could facilitate the agglomeration of skills/excellence and competitiveness in some areas, resulting therefore in geographical unbalances at European level. This paper aims at stimulating a debate on the appropriateness and effectiveness of the governance for research funding in Europe, having in mind that, in a complex system as the European Research Area and its links with industrial competitiveness, it is difficult to evaluate the direct impact of trans-national actions in shaping the evolution of the system itself.
The Syntax of Polish jeden ‘One’ as an Indefinite Determiner
Creators: name: Molinari, Luca
Publisher: name: Fondazione Università Ca’ Foscari Venezia, Italia
Year: 2022

description:

The current literature on Polish jeden ‘one’ focuses on its numeral status, though there is evidence that it is grammaticalizing into an indefinite determiner. This article provides a syntactic analysis of jeden in its different functions, trying to account for its grammaticalization process. Quantificational/adjectival jeden is hosted in the specifier of a DP-internal NumP projection. Indefinite specific jeden is inserted in SpecDP for referential reasons. Moreover, some occurrences of nonspecific jeden may suggest a reanalysis of SpecDP into the head D. These structural changes are in line with other processes of grammaticalization and follow the same Economy principles. This model also builds parallels with Italian and Italo-Romance indefinite determiners.

description: Annali di Ca’ Foscari. Serie occidentale
Digital media is a space where a better life can be rendered possible.pdf
Creators: name: zeroual, khalid
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310408
subject: Life histories

description: In contemporary society, digital media has emerged as a pivotal platform for envisioning and actualizing a better quality of life. By harnessing the power of technology and connectivity, digital media transcends geographical and temporal boundaries, offering a space where diverse voices can converge, exchange ideas, and foster innovation. Moreover, digital media serves as a catalyst for imagination, providing a canvas upon which individuals and communities can envision alternative futures and explore new possibilities
An integrated approach for assessing the bioreceptivity of glazed tiles to phototrophic microorganisms
Creators: name: M. L. Coutinho
name: A. Z. Miller
name: M. A. Rogerio-Candelera
name: J. Mirão
name: L. Cerqueira Alves
name: J. P. Veiga
name: H. Águas
name: S. Pereira
name: A. Lyubchyk
name: M. F. Macedo
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: A laboratory-based methodology was designed to assess the bioreceptivity of glazed tiles. The experimental set-up consisted of multiple steps: manufacturing of pristine and artificially aged glazed tiles, enrichment of phototrophic microorganisms, inoculation of phototrophs on glazed tiles, incubation under optimal conditions and quantification of biomass. In addition, tile intrinsic properties were assessed to determine which material properties contributed to tile bioreceptivity. Biofilm growth and biomass were appraised by digital image analysis, colorimetry and chlorophyll a analysis. SEM, micro-Raman and micro-particle induced X-ray emission analyses were carried out to investigate the biodeteriorating potential of phototrophic microorganisms on the glazed tiles. This practical and multidisciplinary approach showed that the accelerated colonization conditions allowed different types of tile bioreceptivity to be distinguished and to be related to precise characteristics of the material. Aged tiles showed higher bioreceptivity than pristine tiles due to their higher capillarity and permeability. Moreover, biophysical deterioration caused by chasmoendolithic growth was observed on colonized tile surfaces.
Impact of Delftia tsuruhatensis and Achromobacter xylosoxidans on Escherichia coli dual-species biofilms treated with antibiotic agents
Creators: name: Azevedo, Andreia S.
name: Almeida, Carina
name: Pereira, Bruno
name: Melo, Luís F.
name: Azevedo, Nuno F.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Recently it was demonstrated that for urinary tract infections species with a lower or unproven pathogenic potential, such as Delftia tsuruhatensis and Achromobacter xylosoxidans, might interact with conventional pathogenic agents such as Escherichia coli. Here, single- and dual-species biofilms of these microorganisms were characterized in terms of microbial composition over time, the average fitness of E. coli, the spatial organization and the biofilm antimicrobial profile. The results revealed a positive impact of these species on the fitness of E. coli and a greater tolerance to the antibiotic agents. In dual-species biofilms exposed to antibiotics, E. coli was able to dominate the microbial consortia in spite of being the most sensitive strain. This is the first study demonstrating the protective effect of less common species over E. coli under adverse conditions imposed by the use of antibiotic agents.
Enseñanza en línea en los Másteres Universitarios. Casos de estudio de la USAL
Creators: name: García-Peñalvo, F. J.
Publisher: name: Zenodo
Year: 2020
Subjects: eLearning; Máster Universitario; Universidad de Salamanca; Argelia

description: Presentación de casos de estudio de másteres universitarios que se imparten online o en formato semipresencial en la Universidad de Salamanca. Las asignaturas presentadas son “Avances y tendencias en la evaluación de instituciones, organizaciones y programas” del Máster Universitario en Evaluación e Investigación en Organizaciones y Contextos de Aprendizaje y “Gobierno de Tecnologías de la Información” del Máster Universitario en Ingeniería Informática. Esto se realizar en el contexto del proyecto de hermanamiento PAPERS entre la Consejería de Educación de la Junta de Castilla y León y el Ministerio de Educación Superior de Argelia. Esta presentación se realizó el 11 de febrero de 2020 en la misión presencial del proyecto en Argel (Argelia) celebrada entre el 9 y 13 de febrero de 2020.
Ectopic expression of a tobacco vacuolar invertase inhibitor in guard cells confers drought tolerance in Arabidopsis
Creators: name: Chen, Su-Fen
name: Liang, Ke
name: Yin, Dong-Mei
name: Di-An Ni
name: Zhang, Zhi-Guo
name: Ruan, Yong-Ling
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: 60506 Virology

description: There are several hypotheses that explain stomatal behavior. These include the concept of osmoregulation mediated by potassium and its counterions malate and chlorine and the more recent starch–sugar hypothesis. We have previously reported that the activity of the sucrose cleavage enzyme, vacuolar invertase (VIN), is significantly higher in guard cells than in other leaf epidermal cells and its activity is correlated with stomatal aperture. Here, we examined whether VIN indeed controls stomatal movement under normal and drought conditions by transforming Arabidopsis with a tobacco vacuolar invertase inhibitor homolog (Nt-inhh) under the control of an abscisic acid-sensitive and guard cell-specific promoter (AtRab18). The data obtained showed that guard cells of transgenic Arabidopsis plants had lower VIN activity, stomatal aperture and conductance than that of wild-type plants. Moreover, the transgenic plants also displayed higher drought tolerance than wild-type plants. The data indicate that VIN is a promising target for manipulating stomatal function to increase drought tolerance.
title: PORTO FARINA
title: PORTO FARINA
title: Atlas archéologique de la Tunisie
Creators: name: Babelon, Ernest Charles François
name: Babelon, Ernest Charles François > Auteur
name: Cagnat, René Louis Victor > Auteur
name: Reinach, Salomon > Auteur
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: Archéologie
subject: Antiquité
subject: Recherche archéologique
subject: Savoirs (Les)
subject: Cartographie
subject: Atlas
subject: Atlas archéologique

description: [Atlas archéologique de la Tunisie ; Edition spéciale des cartes topographiques publiées par la ministère de la Guerre, accompagnée d’un texte explicatif rédigé par E. Babelon, R. Cagnat et S. Reinach, membres de la Commission de l’Afrique du Nord (1ère série, 60 feuilles au 1/50 000 et notices)]
description: Atlas
description: Atlas-Archeo-Tunisie_008
description: 1/50 000
description: La Méditerranée à la carte
description: Paris
description: Source: Institut de recherche sur le Maghreb contemporain (IRMC); Cité numérique de la Méditerranée (MMSH)
description: Source: La Méditerranée à la carte
description: Source: La Méditerranée à la carte > Atlas archéologique de la Tunisie
description: Relation: https://cinumed.mmsh.univ-aix.fr/idurl/1/96177
description: Coverage: Porto-Farina
description: Coverage: Tunisie
description: Coverage: Antiquité
description: Temporal: Antiquité
description: Provenance: Institut de recherche sur le Maghreb contemporain (IRMC); Cité numérique de la Méditerranée (MMSH)
NC Palladacycles and C,C-chelating phosphorus ylide complexes: synthesis, X-ray characterization, and comparison of the catalytic activity in the Suzuki-Miyaura reaction
Creators: name: Karami, Kazem
name: Mahboubeh Hosseini-Kharat
name: Shirani-Sarmazeh, Zahra
name: Zahedi-Nasab, Reza
name: Rizzoli, Corrado
name: Lipkowski, Janusz
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Six secondary amine palladacycles bearing monodentate ligands (1a, 2a), 1,2-bis(diphenylphosphino)ethane (dppe) and 1,3-bis(diphenylphosphino)propane (dppp) containing bridging and bidentate ligands (1b, 2b–d), and four C,C-type phosphorus ylide complexes containing thiourea (tu) (3a), phenyl isothiocyanate (4a), and bridging and terminal azide groups (5 and 5a) have been synthesized. Resulting complexes have been characterized by elemental analyses, IR, 1H-, 13C{1H}-, and 31P{1H}-NMR spectroscopy with single crystal X-ray structure determination of 1a and 2a. The Pd in 1a and 2a occupies the center of a slightly distorted square planar environment formed by Caryl, Namine, Npyridine, and Cl. The catalytic efficiency of complexes showed that in most cases, amine palladacycles display better catalytic activities than the phosphorus ylide Pd(II) complexes. Comparison between bidentate and bridging dppe complexes showed that dppe-bridged dimer 2d has higher catalytic activity than dppe bidentate complex.
Expected Disruption: Modelling Defensive Interventions in Football
Creators: name: Lamberts, Marc
Publisher: name: Zenodo
Year: 2025

description: This study introduces a machine learning framework, named Expected Disruption, to predict defensive interventions in professional football using detailed spatiotemporal event data from the 2024–2025 Czech League season. The framework integrates expected threat (xT) modeling with pass characteristics—such as angle, length, and type—and pressing intensity to identify when and where on the pitch defensive actions are most likely to occur.

Passes are enriched with context-aware metrics like xPass (expected pass success) and PP90 (pressures per 90 minutes). The model learns from spatial zones, player roles, and event outcomes, using a Random Forest Classifier. Results demonstrate strong predictive power with a ROC AUC of 0.81. This research contributes to modern football analytics by offering tools to evaluate team pressing strategies, identify key defenders, and analyse riskier passing patterns in real time.

The primary motivation behind Expected Disruption is to provide a repeatable, scalable way to model defensive value, something historically difficult due to data limitations. By utilising widely available event data, this model bridges a critical gap in the analytics space, empowering coaches, analysts, and scouts with a practical tool to understand defensive efficiency. Moreover, the integration of player-specific pressure statistics (PP90) allows this framework to recognise not just the outcome of an event, but also the behaviours and tendencies that lead to it.
Neural oscillations in antipsychotic-naïve patients with a first psychotic episode
Creators: name: Ramyead, Avinash
name: Studerus, Erich
name: Kometer, Michael
name: Heitz, Ulrike
name: Gschwandtner, Ute
name: Fuhr, Peter
name: Riecher-Rössler, Anita
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objectives: In chronic schizophrenic psychoses, oscillatory abnormalities predominantly occur in prefrontal cortical regions and are associated with reduced communication across cortical areas. Nevertheless, it remains unclear whether similar alterations can be observed in patients with a first episode of psychosis (FEP), a state characterised by pathological features occurring in both late prodromal patients and initial phases of frank schizophrenic psychoses. Methods: We assessed resting-state electroencephalographic data of 31 antipsychotic-naïve FEP patients and 29 healthy controls (HC). We investigated the three-dimensional (3D) current source density (CSD) distribution and lagged phase synchronisation (LPS) of oscillations across small-scale and large-scale brain networks. We additionally investigated LPS relationships with clinical symptoms using linear mixed-effects models. Results: Compared to HC, FEP patients demonstrated abnormal CSD distributions in frontal areas of the brain; while decreased oscillations were found in the low frequencies, an increase was reported in the high frequencies (P Conclusions: These results indicate that in addition to prefrontal cortical abnormalities, altered synchronised neural oscillations are also present, suggesting possible disruptions in cortico-cortical communications. These findings provide new insights into the pathophysiological mechanisms of emerging schizophrenic psychoses.
Novel agonists of free fatty acid receptor 1 (GPR40) based on 3-(1,3,4-thiadiazol-2-yl)propanoic acid scaffold
Creators: name: Krasavin, Mikhail
name: Lukin, Alexey
name: Zhurilo, Nikolay
name: Kovalenko, Alexey
name: Zahanich, Ihor
name: Zozulya, Sergey
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: 1,3,4-Thiadiazole was explored as a more polar, heterocyclic replacement for the phenyl ring in the 3-arylpropionic acid pharmacophore present in the majority of GPR40 agonists. Out of 13 compounds synthesized using a flexible, three-step protocol (involving no chromatographic purification), four compounds were confirmed to activate the target in micromolar concentration range. While the potency of the series should be subject of further optimization, the remarkable aqueous solubility and microsomal stability observed for the lead compound (8g) apparently attests to this new scaffold’s high promise in the GPR40 agonist field.
title: Journal Kunst.Gestaltung.Musik.Bühne.Wissen
Creators: name: Universität Der Künste Berlin
Publisher: name: Der Präsident der UdK Berlin
Year: 2019

description: 2019,12 - 2020,3
description: Journal Kunst.Gestaltung.Musik.Bühne.Wissen, 2019,12 - 2020,3
NC Palladacycles and C,C-chelating phosphorus ylide complexes: Synthesis, X-ray characterization and comparison of the catalytic activity in the Suzuki-Miyaura reaction
Creators: name: Karami, Kazem
name: Mahboubeh Hosseini-Kharat
name: Shirani-Sarmazeh, Zahra
name: Zahedi-Nasab, Reza
name: Rizzoli, Corrado
name: Lipkowski, Janusz
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: Six secondary amine palladacycles bearing monodentate ligands (1a, 2a) and 1,2-bis(diphenylphosphino)ethane (dppe) and 1,3-bis(diphenylphosphino)propane (dppp) containing bridging and bidentate ligands (1b, 2b-d), and four C,C-type phosphorus ylide complexes containing thiourea (tu) (3a), phenyl isothiocyanate (4a), bridging and terminal azide groups (5 and 5a) have been synthesized. Resulting complexes have been characterized by elemental analyses, IR, 1H-, 13C{1H}- and 31P{1H}-NMR spectroscopy with single crystal X-ray structure determination of 1a and 2a. The Pd in 1a and 2a occupy the center of a slightly distorted square planar environment formed by Caryl, Namine, Npyridine and Cl. The catalytic efficiency of complexes showed that in most cases amine palladacycles display better catalytic activities than the phosphorus ylide Pd(II) complexes. Comparison between bidentate and bridging dppe complexes showed that dppe bridged dimer 2d has higher catalytic activity than dppe bidentate complex.
Crystal structure of K[PtCl3(caffeine)] and its interactions with important nitrogen-donor ligands
Creators: name: Snežana Jovanović
name: Puchta, Ralph
name: Klisurić, Olivera
name: Živadin D. Bugarčić
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences

description: The crystal structure of K[PtCl3(caffeine)] was determined. The coordination geometry around platinum is square-planar formed by N9 of the caffeine ligand and three Cl− ions. The bond lengths and angles of K[PtCl3(caffeine)] were compared with those reported for [PtCl3(caffeine)]− and K[PtCl3(theobromine)]. At the level of the statistical significance of the data we have compared, no differences in the bond distances and angles for any of these compounds were noticed. Weak interactions between K+ and Cl− are responsible for the formation of 1-D polymeric chains in the crystal structure of the complex. The interactions of K[PtCl3(caffeine)] with inosine (Ino) and guanosine-5′-monophosphate (5′-GMP) were studied by 1H NMR spectroscopy at 295 K in D2O in a molar ratio of 1 : 1. The results indicate formation of the reaction product [PtCl3(Nu)] (Nu=Ino or 5′-GMP) with the release of caffeine from the coordination sphere of the starting complex. The higher stability of the bond between the Pt(II) ion and Ino or 5′-GMP compared to the stability of the platinum–caffeine bond is confirmed by density functional theory calculations (B3LYP/LANL2DZp) using as models 9-methylhypoxanthine and 9-methylguanine.
Neural Oscillations in Antipsychotic-Naïve Patients with a First Psychotic Episode
Creators: name: Ramyead, Avinash
name: Studerus, Erich
name: Kometer, Michael
name: Heitz, Ulrike
name: Gschwandtner, Ute
name: Fuhr, Peter
name: Riecher-Rössler, Anita
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Neuroscience
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Objectives: In chronic schizophrenic psychoses, oscillatory abnormalities predominantly occur in prefrontal cortical regions and are associated with reduced communication across cortical areas. Nevertheless, it remains unclear whether similar alterations can be observed in patients with a first-episode of psychosis (FEP), a state characterized by pathological features occurring in both late prodromal patients and initial phases of frank schizophrenic psychoses. Methods: We assessed resting-state EEG data of 31 antipsychotic-naïve FEP patients and 29 healthy-controls (HC). We investigated the 3-dimensional current-source density (CSD) distribution and lagged phase synchronization (LPS) of oscillations across small-scale and large-scale brain networks. We additionally investigated LPS relationships with clinical symptoms using linear mixed-effects models. Results: Compared to HC, FEP patients demonstrated abnormal CSD distributions in frontal areas of the brain; while decreased oscillations were found in the low frequencies, an increase was reported in the high frequencies (p<0.01). Patients also exhibited deviant LPS in the high frequencies, whose dynamics changed over increasing 3D cortico-cortical distances and increasing psychotic symptoms. Conclusions: These results indicate that in addition to prefrontal cortical abnormalities, altered synchronized neural oscillations are also present, suggesting possible disruptions in cortico-cortical communications. These findings provide new insights into the pathophysiological mechanisms of emerging schizophrenic psychoses.
RESPONSABILIDADE CIVIL POR ABANDONO AFETIVO: UMA REVISÃO SISTEMÁTICA DE LITERATURA
Creators: name: Ginamara de Carvalho Purcina ROCHA
name: Kamila Nunes ROSALVE
name: Antônio José dos SANTOS
name: Jocirley de OLIVEIRA
Publisher: name: Zenodo
Year: 2024
Subjects: Responsabilidade Civil
Abandono Afetivo
Dano
Família

description: RESUMO

Este artigo apresenta uma revisão sistemática da literatura sobre a responsabilidade civil por abandono afetivo, utilizando uma abordagem qualitativa para analisar as principais obras e estudos que tratam do tema. O abandono afetivo refere-se à omissão de cuidados, afeto e atenção por parte dos pais ou responsáveis, resultando em danos emocionais e psicológicos aos filhos. A responsabilidade civil, nesse contexto, surge como uma possibilidade de reparação dos danos sofridos. A pesquisa bibliográfica envolveu a identificação, seleção e análise crítica de publicações relevantes, explorando as fundamentações jurídicas, as decisões judiciais e as implicações sociais desta responsabilidade. Os resultados indicam que, embora haja um crescente reconhecimento jurídico do abandono afetivo, ainda existem desafios significativos na aplicação uniforme da responsabilidade civil nesta área, com variações nos critérios adotados pelos tribunais para a configuração do abandono e concessão de indenizações. O artigo conclui que há uma tendência de evolução no entendimento jurídico sobre o tema, mas aponta para a necessidade de maior clareza normativa e jurisprudencial.
Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives
Creators: name: Eissa, Ahmed G.
name: Blaxland, James A.
name: Williams, Rhodri O.
name: Metwally, Kamel A.
name: Sobhy M. El-Adl
name: El-Sayed M. Lashine
name: Baillie, Leslie W. J.
name: Simons, Claire
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: The synthesis of a series of benzimidazole-N-benzylpropan-1-amines and adenine-N-benzylpropan-1-amines is described. Subsequent evaluation against two strains of the anaerobic bacterium Clostridium difficile was performed with three amine derivatives displaying MIC values of 16 μg/mL. Molecular docking studies of the described amines determined that the amines interact within two active site pockets of C. difficile methionyl tRNA synthetase with methoxy substituents in the benzyl ring and an adenine biaryl moiety resulting in optimal binding interactions.
Ordonnance du conseil souverain, qui prescrit au Geôlier de porter lui-même, sa femme ou un valet approuvé par la cour, les vivres aux prisonniers, sans pouvoir se servir d'autres personnes
Creators: name: Plouvain, Pierre-Antoine-Samuel-Joseph (1754-1832)
name: Six, Philippe-Josse-Auguste-Joseph (1732-1793)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: Alimentation
Discipline pénitentiaire
Population pénitentiaire
Établissement pénitentiaire

description: Source: http://nordnum.univ-lille.fr/ark:/72505/a0115224001360im5Ol/from/a011522400136ypxWl2
description: Coverage: Parlement de Flandre
description: created: 23/10/2018
description: created: 15/12/1684
SOBIQ ITTIFOQ "QAYTA QURISH" SIYOSATINING TANAZZULI: O'ZBEKISTON ZIYOLILARINING SIYOSIY JARAYONLARGA MUNOSABATI
Creators: name: Ochilova, Dilobar
Publisher: name: Zenodo
Year: 2024

description: SSSR parchalanganidan keyin xalqaro olimlar Sovet respublikalarining mustaqillikka va kapitalizmga o‘tish jarayonidagi taqdiriga e’tibor qaratdilar. Shu bilan birga, Qozog‘iston, Qirg‘iziston, Tojikiston, Turkmaniston va O‘zbekistondan iborat besh respublika vakili bo‘lgan Markaziy Osiyoga kamroq e’tibor qaratildi va nisbatan kam o‘rganilgan. Buning asosiy sababi sifatida mintaqaning rivojlangan g‘arb olamidan uzoqligi (Boltiqbo‘yi yoki Kavkaz mintaqasiga nisabatan), dengizgacha bo‘lgan masofa uzoqligi, g‘arb bilan integratsion aloqalarning olib borilishi sustligi bilan bog‘lash mumkin.
Actiheart validation of time-domain heart rate variability
Creators: name: Schaarup, Jonas
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 320199
subject: Cardiovascular medicine and haematology not elsewhere classified
classificationCode: 320208
subject: Endocrinology

description: # BackgroundFrom the Actiheart recordings in ADDITION-PRO study, there are heart rate data every 30 seconds with a 95 % prediction interval. We have developed an algorithm that calculates HRV, which calculates the distribution of interbeat interval (IBI) in each 30-second epoch and includes the generated interval in the r package called RHRV. The document validates the algorithm on data set from physionet with all available IBI.# Use caseAs many wearable devices measure periodic IBI or mean heart rate with a prediction interval, we need to test whether we can derive standard time-domain HRV measures from incomplete IBI during the whole worn period. Frequency-domain HRV measures are not relevant for this purpose, as we would require all IBI data recorded during the period. The algorithm for this is based on the RHRV package (version 4.2.7) and creates an automatic pipeline to calculate time-domain HRV based on the input of sequences of IBI. Contact Jonas R Schaarup (jfrscha@ph.au.dk), for further description of the algorithm or if needed help with implementation. With full access to IBI, frequency-domain measures can be implemented in this pipeline. Reference to RHRV package:*Heart Rate Variability Analysis with the R package RHRV, C.A. García, A. Otero, X.A. Vila, M.J. Lado, L. Rodríguez-Liñares, J.M. Presedo, and A.J. Médez. Springer International Publishing, 2017. Springer book page*
# AimTo validate time-domain HRV measures based on 30 second epoch including mean heart rate data and 95 % prediction interval with time-domain HRV measures with full access to all IBI
# Data description
We include 76 healthy subject with 24-hour holter recordings. Description of the full data set can be found in the reference below.
Reference to dataset:
*Irurzun, I. M., Garavaglia, L., Defeo, M. M., & Thomas Mailland, J. (2021). RR interval time series from healthy subjects (version 1.0.0). PhysioNet. https://doi.org/10.13026/51yd-d219.*
# MethodsWe calculated 30 second mean HR with a 95% prediction interval based on the last 8 heart beats in the 30 second segment.We tested the algorithm for HRV measures based generated IBI from the 30 sec mean HR and compared it HRV calculated from the actual heart beats interbeat intervals. We plotted the generated HRV and the actual HRV and performed spearman correlation between the two HRV measures.
title: V2_DU_LettreY
Creators: name: Basnage de Beauval, Henri
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: Ceci est la V2 du Dictionnaire universel, revu et corrigé en 1701 par Basnage de Beauval. Cette version a été obtenue avec GROBID dictionaries, après adaptation du système et renentraînement en juillet 2020.
Delaying berry ripening through manipulating leaf area to fruit ratio
Creators: name: Martínez De Toda, F.
name: Balda, P.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The viticulture practices have always been focused on the production of grapes with higher sugar level, and this tendency has been pronounced by the climate change. The objective consists on delaying berry ripeness by decreasing the ratio between the leaf area and yield, performing intense trimming treatments after berry set and establishing the consequences on grapevine productivity in the following years. Severe shoot trimming with two different intensity treatments were done during a 3-year period (2010-2012). Phenological, vegetative and productive parameters were examined. Veraison date was delayed around twenty days. Regarding the same harvesting date, the trim treatments had lower soluble solids level (15 % reduction), lower pH (0.1-0.3) and less total anthocyanin content (10-27 % reduction). The trim effect was also reflected in berry weight; as a consequence of that, bunch size and yield were also reduced by around 9 and 15 %. Overall, single trim treatment was superior to double trim treatment because it can achieve the same results in delayed ripening, reduced °Brix, pH and production but with a smaller reduction in anthocyanin content and without having any negative impact on following years.
description: VITIS - Journal of Grapevine Research, Vol. 52 No. 4 (2013): Vitis
Nitrogen fertilizer and EDTA effect on Cannabis sativa growth and Phytoextraction of heavy metals (Cu and Zn) contaminated soil
Creators: name: Eshabel Andra
Publisher: name: figshare
Year: 2016
Subjects: subject: Biotechnology
subject: 99901 Agricultural Engineering
subject: FOS: Other engineering and technologies
subject: 140201 Agricultural Economics
subject: FOS: Economics and business
subject: Education
subject: Botany
subject: Plant Biology
subject: FOS: Biological sciences
subject: 60704 Plant Pathology

description: Heavy metals in soil, water and air is a great concern. Toxic heavy metals ultimately affect plant, Animals, and through food chain directly influence human life. In present study, the effect of heavy metals (Cu, Zn), Nfertilizers and EDTA on growth and biomass of cannibus sativa plant was evaluated. The Cu and Zn phytoextraction potential of Cannabis sativa plant under various treatments of N-fertilizers and EDTA were investigated. Metals (Cu, Zn) significantly reduced the plant growth and biomass while the fertilizer application increased the plant growth and biomass under metals stress. The application of EDTA alone increased the metals (Cu, Zn) accumulation in root, stem and leaves but reduced the plant height, root length and biomass. The maximum accumulation of Cu in root (75 μg/g DW), stem (55 μg/g DW) and in leaves (45 μg/g DW) was found with EDTA treatment (T3). Maximum Zn concentration in Leaves (155 μg/g DW) and root (148 μg/g DW) was observed in plants treated with EDTA. Conclusively, metals contaminated soil considerably reduced plant growth and biomass while metals in combination with N-Fertilizer the plant growth and biomass was enhanced. Addition of EDTA significantly enhanced phytoaccumulation of metals (Zn, Cu).