cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
V-ATPase regulation of Hypoxia Inducible transcription Factors
Creators: name: Miles, Anna Louise
Publisher: name: Apollo - University of Cambridge Repository
Year: 2018
Subjects: CCDC115
HIF
Iron
PHD
TMEM199
Vacuolar ATPase
Vma12p
Vma22p
Ferritinophagy
Prolyl hydroxylation
Transferrin
Transferrin receptor
Lysosomes
Acidification
Hypoxia Inducible Factors
V-ATPase
Proteasome
Hypoxic response pathway
Endo-lysosomal degradation
IRP2
IRE

description: Metazoans have evolved conserved mechanisms to promote cell survival under low oxygen tensions by initiating a transcriptional cascade centered on the action of Hypoxia Inducible transcription Factors (HIFs). In aerobic conditions, HIFs are inactivated by ubiquitin-proteasome-mediated degradation of their a subunit, which is dependent on prolyl hydroxylation by 2-oxoglutarate (2-OG) and Fe(II)-dependent prolyl hydroxylases (PHDs). In hypoxia, HIF-$\alpha$ is no longer hydroxylated and is therefore stabilised, activating a global transcriptional response to ensure cell survival. Interestingly, HIFs can also be activated in aerobic conditions, however the mechanisms of this oxygen-independent regulation are poorly understood. Here, I have explored the role of the vacuolar H+-ATPase (V-ATPase), the major proton pump for acidifying intracellular vesicles and facilitating lysosomal degradation, in regulating HIF-$\alpha$ turnover. Unbiased forward genetic screens in near-haploid human cells identified that disruption of the V-ATPase leads to activation of HIFs in aerobic conditions. Rather than preventing the lysosomal degradation of HIF-$\alpha$, I found that V-ATPase inhibition indirectly affects the canonical proteasome-mediated degradation of HIF-$\alpha$ isoforms by altering the intracellular iron pool and preventing HIF-$\alpha$ prolyl hydroxylation. In parallel, I characterised two putative mammalian V-ATPase assembly proteins, TMEM199 and CCDC115, identified by the forward genetic screen and subsequent mass spectrometry analysis. I confirmed that both TMEM199 and CCDC115 are required for V-ATPase function, and established assays to determine how TMEM199 and CCDC115 associate with components of the core V-ATPase complex. Lastly, to measure how V-ATPase activity leads to changes in the labile iron pool, I developed an endogenous iron reporter using CRISPR-Cas9 knock-in technology. This approach confirmed that iron homeostasis is impaired during V-ATPase inhibition, and demonstrated that exogenous ferric iron can restore the labile iron pool in a transferrin-independent manner. Together my studies highlight a crucial link between V-ATPase activity, iron homeostasis, and the hypoxic response pathway.
description: Medical Research Council Funding MR/K50127X/1
General upper bounds for distributing conferencing keys in arbitrary quantum networks
Creators: name: Pirandola, Stefano
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: Secure quantum conferencing refers to a protocol where a number of trusted users generate exactly the same secret key to confidentially broadcast private messages. By a modification of the techniques first introduced in [Pirandola, arXiv:1601.00966], we derive a single-letter upper bound for the maximal rates of secure conferencing in a quantum network with arbitrary topology, where the users are allowed to perform the most powerful local operations assisted by two-way classical communications, and the quantum systems are routed according to the most efficient multipath flooding strategies. More precisely, our analysis allows us to bound the ultimate rates that are achievable by single-message multiple-multicast protocols, where N senders distribute N independent secret keys, and each key is to be shared with an ensemble of M receivers.
description: Published in the inaugural issue of IET Quantum Communication
Urban agriculture in the United States: reconnecting consumers and producers
Creators: name: Dimitri, Carolyn
name: Oberholtzer, Lydia
name: Pressman, Andy
name: Dimitri, Carolyn
name: Oberholtzer, Lydia
name: Pressman, Andy
Publisher: name: Unknown
Year: 2015
Subjects: Agribusiness
Consumer/Household Economics
Farm Management

description: Do not cite. ​This piece is an early draft of a paper due to be published in 2016 by British Food Journal. A full citation to the formal publication will be provided here when available.
Hadronic Correlators from All-point Quark Propagators
Creators: name: Duncan, A.
name: Eichten, E.
name: Yoo, J.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: A method for computing all-point quark propagators is applied to a variety of processes of physical interest in lattice QCD. The method allows, for example, efficient calculation of disconnected parts and full momentum-space 2 and 3 point functions. Examples discussed include: extraction of chiral Lagrangian parameters from current correlators, the pion form factor, and the unquenched eta-prime.
description: LATTICE01(Algorithms and Machines)
Elastic properties of hot isostatically pressed magnesium diboride
Creators: name: Nesterenko, V. F.
name: Gu, Y.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Powder of magnesium diboride was hot isostatically pressed using three qualitatively different cycles: cooling under pressure (DMCUP), "standard" cycle with pressure and temperature reduced simultaneously and isothermal presure release. Elastic properties of dense material were measured at normal conditions using resonant ultrasound specroscopy (RUS) method. The highest value of density (2.66 g/cc) and elastic moduli (Young's modulus 273.5 GPa, bulk modulus 143.9 GPa, Poisson's ratio 0.183) correspond to the sample processed using DMCUP cycle. These data agree very well with some theoretical predictions based on quantum mechanics calculations. Effect of lower density on elastic constants is consistent with theoretical approach based on elasticity theory taking into account effect of low porosity.
description: 14 pages, 2 figures, 1 table; data are added for sample prepared with another HIP cycle, larger number of resonances is used for calculation of elastic constants
Longitudinal short-distance constraints for the hadronic light-by-light contribution to $(g-2)_μ$ with large-$N_c$ Regge models
Creators: name: Colangelo, Gilberto
name: Hagelstein, Franziska
name: Hoferichter, Martin
name: Laub, Laetitia
name: Stoffer, Peter
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: While the low-energy part of the hadronic light-by-light (HLbL) tensor can be constrained from data using dispersion relations, for a full evaluation of its contribution to the anomalous magnetic moment of the muon $(g-2)_μ$ also mixed- and high-energy regions need to be estimated. Both can be addressed within the operator product expansion (OPE), either for configurations where all photon virtualities become large or one of them remains finite. Imposing such short-distance constraints (SDCs) on the HLbL tensor is thus a major aspect of a model-independent approach towards HLbL scattering. Here, we focus on longitudinal SDCs, which concern the amplitudes containing the pseudoscalar-pole contributions from $π^0$, $η$, $η'$. Since these conditions cannot be fulfilled by a finite number of pseudoscalar poles, we consider a tower of excited pseudoscalars, constraining their masses and transition form factors from Regge theory, the OPE, and phenomenology. Implementing a matching of the resulting expressions for the HLbL tensor onto the perturbative QCD quark loop, we are able to further constrain our calculation and significantly reduce its model dependence. We find that especially for the $π^0$ the corresponding increase of the HLbL contribution is much smaller than previous prescriptions in the literature would imply. Overall, we estimate that longitudinal SDCs increase the HLbL contribution by $Δa_μ^\text{LSDC}=13(6)\times 10^{-11}$. This number does not include the contribution from the charm quark, for which we find $a_μ^{c\text{-quark}}=3(1)\times 10^{-11}$.
description: 85 pages, 33 figures, 5 tables; journal version, includes reply to arXiv:1911.05874
Questions and Remarks About Clans in Multiparticle Dynamics
Creators: name: Giovannini, Alberto
name: Ugoccioni, Roberto
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The fact that several important effects in multiparticle dynamics, on which QCD has not yet satisfactory predictions, have been interpreted in terms of the validity of negative binomial (Pascal) regularity and related clan properties at the level of simpler substructures, raises intriguing questions on clan properties in all classes of collisions, the main one being whether clans are observable objects or merely a mathematical concept. We approach this problem by studying clan masses and rapidity distributions in each substructure for e+e- annihilation and hh collisions, and find that such properties can indeed characterise the different components. These results support the idea that clans could be observable, a challenging problem for future experiments.
description: 11 pages; 3 figures; latex 2e and amsmath
Study of Low beta-y Straight Section in SPEAR 3
Creators: name: Nosochkov, Y.
name: Corbett, J.
name: Rabedeau, T.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: The SPEAR 3 light source has two 7.6 m straight sections one of which is available for new insertion devices (ID). By reducing the vertical beta function at the center of the straight from 9.8 m to 1.5 m, the beam size can be decreased from 44 to 17 microns to reduce the ID gap, but the ID length may be limited by the increased beta-y variation in the ID. Alternatively, a ``double waist'' optics with two symmetric low beta-y locations and a chicane may be considered to implement two IDs. In this paper, we discuss the low beta-y optics, effects on the beam dynamic aperture, and the ID parameters needed to maximize photon flux density and brightness while maintaining electron beam lifetime.
description: PAC2001, 4 pages
Additional file 1 of Design, synthesis, and biological activity of novel 1,2,4-oxadiazole derivatives
Creators: name: Zhu, Lingzhi
name: Zeng, Huanan
name: Liu, Dan
name: Fu, Yun
name: Wu, Qiong
name: Song, Baoan
name: Gan, Xiuhai
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Plant Biology

description: Additional file 1. The 1H NMR, 13C NMR, and HRMS data of target compounds.
REGIONAL STUDY OF THE LAND PRICE AND LAND VALUE IN HUNGARY – BASED ON THE EXPERIENCE OF FARM ACCOUNTING DATA NETWORK
Creators: name: Baranyai, Zsolt
name: Vinogradov, Szergej
name: Vásáry, Miklós
name: Naárné Tóth, Zsuzsanna
name: Baranyai, Zsolt
name: Vinogradov, Szergej
name: Vásáry, Miklós
name: Naárné Tóth, Zsuzsanna
Publisher: name: Unknown
Year: 2014
Subjects: subject: Demand and Price Analysis
subject: Land Economics/Use
subject: land price
subject: land value
subject: full liberalization of the land market
subject: significant differences in price levels
subject: partial factor calculation yield
subject: földár
subject: földérték
subject: földpiac teljes liberalizálása
subject: árszint-különbségek
subject: parciális tényezőhozadék számítás

description: As it is well known, in Hungary – similary to most of the new EU Member States joined in 2004 and 2007 (EU 12) – the price of agricultural land is significantly lower than in the old EU Member States (EU 15). Although in the accession period experts indicated significant differences in price levels, that is they will decrease within a few years of the EU membership and the full liberalization of the land market will not cause dastric socio-economic problems. The harmonization of expected land prices did not occur or it occured to a different extent at the same time full liberalization is approaching fast. This study is based on this situation, which aims to elucidate those factros which can be named as reasons for the formation of the difference between land prices experienced in Hungary and Western Europe. ---------------------------------------------------- Mint az jól ismert, Magyarországon – hasonlóan a legtöbb 2004-ben, illetve 2007-ben csatlakozott új európai uniós tagállamhoz (EU12) – jelentősen alacsonyabb a mezőgazdasági földek ára, mint az EU régebbi (EU15) tagországaiban. A csatlakozás időszakában a szakmai körök bár azt valószínűsítették, hogy az EU tagságot követő néhány éven belül ezek a jelentős árszint-különbségek csökkenni fognak és a földpiac teljes liberalizálása nem fog drasztikus társadalmi-gazdasági problémákat okozni. A földárak várt harmonizációja ugyanakkor nem, illetve nem olyan mértékben következett be, a teljes liberalizáció viszont vészesen közeleg. Ezt a szituációt alapul véve, kutatásunk kettős célt fogalmaz meg: egyrészt, hogy helyzetértékelést adjon – regionális szinten – a földárak alakulásáról a 2006-2010 közötti időszakra vonatkozóan, másrészt a kapcsolódó közgazdasági elmélet bázisán megvizsgálja azt, hogy milyen összefüggés van a föld közgazdasági értelemben vett értéke, illetve az ára között.
The Effects Of Vermicompost Application On Phenypropanoid Metabolism Of Basil (Ocimum basilicum L.) Chemotypes
Creators: name: Türkay, İlker
Publisher: name: Zenodo
Year: 2021
Subjects: Phenylpropanoid
Basil
Gene expression
Metabolism
Organic fertilizers
Vermicompost

description: In this thesis, the effects of solid vermicompost (KV) and liquid vermicompost (SV) applications on phenylpropene accumulation and expression profiles of PAL, 4CL, EGS, EOMT and CVOMT genes in peltate glandular trichomes isolated from young leaves of methylcavicol chemotype (LR10A) and methyleugenol chemotype (LR25A) basils were investigated. For this purpose, 0%, 10% and 25% KV to root regions of chemotypes; pure water, 10% and 25% concentrations of SV were applied to the leaves by spraying. It was determined that KV applications decreased the accumulation of methylchavicol and methyleugenol and the expressions of EOMT and CVOMT genes in methylchavicol chemotype basils, whereas increased them in methyleugenol chemotype basils (p<0.05). The application of 10% SV to methylchavicol chemotypes increased the percentage of chavicol and methyleugenol, and 25% SV application increased the percentage of eugenol and methylchavicol. The application of 10% SV increased PAL, EOMT and CVOMT gene expressions, whereas 25% SV application generally decreased gene expressions. SV applications to methyleugenol chemotypes decreased the ratio of eugenol and methyleugenol, but did not cause a significant change in the ratio of methylchavicol (p<0.05). In methylogenol chemotype basils, SV treatments increased the PAL gene expression in direct proportion with the increase in dose, while it had different effects on the expressions of other genes. As a result, significant differences were found in phenylpropene content and gene expression profiles in the peltate glandular hairs, depending on the form and dose of the applied vermicompost and the chemotypic differences of basils.
MOESM2 of European Medicines Agency Policy 0070: an exploratory review of data utility in clinical study reports for academic research
Creators: name: Jean-Marc Ferran
name: Nevitt, Sarah
Publisher: name: figshare
Year: 2019
Subjects: Science Policy

description: Additional file 2. Correspondence with authors of journal publications using CSRs for academic research. A list of semi-structured interview questions posed to corresponding authors of journal publications using CSRs for academic research and corresponding author responses to questions.
Control landscape for ultrafast manipulation by a qubit
Creators: name: Pechen, Alexander
name: Il'in, Nikolay
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: In this work we study extrema of objective functionals for ultrafast manipulation by a qubit. Traps are extrema of the objective functionals which are optimal for manipulation by quantum systems only locally but not globally. Much effort in prior works was devoted to the analysis of traps for quantum systems controlled by long enough laser pulses and, for example, manipulation by a qubit with long control pulses was shown to be trap-free. Ultrafast femtosecond and attosecond control becomes now widely applicable that motivates the necessity for the analysis of traps on the ultrafast time scale. We do such analysis for a qubit and show that ultrafast state transfer in a qubit remains trap-free for a wide range of the initial and final states of the qubit. We prove that for this range the probability of transition between the initial and the final states has a saddle but has no traps.
A Comprehensive Study of Pulse Profile Evolution in SGR 1806-20 & SGR 1900+14 with the RXTE PCA
Creators: name: Gogus, Ersin
name: Kouveliotou, Chryssa
name: Woods, Peter M.
name: Finger, Mark H.
name: van der Klis, Michiel
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Soft Gamma Repeaters undergo pulse profile changes in connection with their burst activity. Here we present a comprehensive pulse profile history of SGR 1806-20 and SGR 1900+14 in three energy bands using Rossi X-ray Timing Explorer/Proportional Counter Array observations performed between 1996 and 2001. Using the Fourier harmonic powers of pulse profiles, we quantify the pulse shape evolution. Moreover, we determined the RMS pulsed count rates (PCRs) of each profile. We show that the pulse profiles of SGR 1806$-$20 remain single pulsed showing only modest changes for most of our observing span, while those of SGR 1900+14 change remarkably in all energy bands. Highly significant pulsations from SGR 1900+14 following the 1998 August 27 and 2001 April 18 bursts enabled us to study not only the decay of PCRs in different energy bands but also their correlations with each other.
description: 23 pages, accepted for publication in ApJ
The dynamics of securitization and desecuritization in Ethiopia: the case of civil society organizations (CSOs)
Creators: name: Yimer, Nigusu Adem
name: Subaşi, Turgut
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Science Policy
Biological Sciences not elsewhere classified
Developmental Biology

description: While Civil Society Organizations (CSOs) play a crucial role in the development endeavors of Ethiopia, the Ethiopian People’s Revolutionary Democratic Front (EPRDF) prefers to adopt a securitization approach, depicting their activities as a potential danger, counterproductive, amplify the voices of foreign actors, and ‘rent-seeking’. According to reports, CSOs have been characterized and delineated as political humanitarian, driven by self-interest, and as entities that amplify the voices of foreign actors. This study aims to elucidate the processes by which CSOs in Ethiopia were securitized and desecuritized, respectively, by the EPRDF government led by the Tigray People’s Liberation Front (TPLF) and the Prosperity Party. The paper explores the securitization and desecuritization dynamics of CSOs in Ethiopia, with a specific focus on the underlying reasons that contribute to these processes. This study also investigates the consequences of the EPRDF securitization measures on CSOs, as well as the potential obstacles faced by CSOs in Ethiopia. The analytical framework utilized in this study is the application of the notion of securitization as proposed by the Copenhagen School (CS). By constructing the data from unrevised documents, the paper characterizes the dynamics of securitization and desecuritization of CSOs in Ethiopia through an interpretive analytical approach. The primary goal of this research was to investigate the dynamics of securitization and desecuritization of Civil Society Organizations (CSOs) in Ethiopia. Throughout its tenure, the Ethiopian People’s Revolutionary Democratic Front (EPRDF) has portrayed Civil Society Organizations as irresponsible selfish servants of their own interests, representatives of foreign governments, advocates for foreign interests, ardent proponents of neoliberalism, political humanitarians, and proponents of color revolutions. Furthermore, CSOs have been viewed as ‘rent-seeking’, counterproductive, and an impediment to the country’s progress. All along its securitization activities, the TPLF led EPRDF used Ethiopia as a shield to defend its referent objects, which included democratic centralism, abiyotawi democracy (revolutionary democracy), and limatawi menigist (developmental state) philosophy. This was worked through constant demonization and securitization of CSOs developmental activities. But starting in 2018, the recently established Prosperity Party (PP) has taken a proactive stance in the effort to depoliticize and desecuritize the CSOs’ development activities.
MOESM1 of Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
Creators: name: Rey, Manuel Del
name: Valín, Álvaro
name: Usategui, Alicia
name: Ergueta, Sandra
name: Martín, Eduardo
name: Municio, Cristina
name: Cañete, Juan
name: Blanco, Francisco
name: Criado, Gabriel
name: Pablos, José
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Computational Biology

description: Additional file 1: Figure S1. Double hsp47/p16 and CD68/p16 labelling of synovial tissues. Representative images of synovial tissues labelled for hsp47 and CD68 (red), p16 (green) and merge. Arrows indicate senescent double positive cells for each label.
2019 Commonwealth Fund International Health Policy Survey of Primary Care Doctors
Creators: name: Commonwealth Fund
Publisher: name: Roper Center for Public Opinion Research
Year: 2021

description: Performance rating of healthcare system (1); satisfaction with practicing medicine (8); quality of medical care (8); other health care professionals who work on team (20); various ways of providing care (3); appointment availability (3); practice preparedness for patients with various needs (6); use of personnel to monitor follow-up care (1); treatment for chronic conditions (10); end of life conversations (2); specialists (6); hospitalizations (2); home-based nursing care (2); assessing patients for social needs (7); coordinating care with social services (5); electronic medical records/communication (15); national "Electronic Patient Record" in Switzerland (1); reviewing data on patients' care (5); time spent on various tasks (9); stress of job (1); future career plans (6); workload (1); low value/wasteful treatments (4); weekly hours worked/patients seen (4); type of practice (5); sources of revenue (6); types of patients (3); accepting new patients (6); cancer patients (3); quality control/improvement (1); patient experiences (6); digital care visits (33).
Time-changed Dirac-Fokker-Planck equations on the lattice
Creators: name: Faustino, N.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Mathematical Physics (math-ph)
subject: Analysis of PDEs (math.AP)
subject: Functional Analysis (math.FA)
subject: Probability (math.PR)
subject: FOS: Physical sciences
subject: FOS: Mathematics
subject: 30G35, 35Q41, 42B05, 33E12, 35Q84, 39A12, 44A20

description: A time-changed discretization for the Dirac equation is proposed. More precisely, we consider a Dirac equation with discrete space and continuous time perturbed by a time-dependent diffusion term $σ^2Ht^{2H-1}$ that seamlessly describes a latticizing version of the time-changed Fokker-Planck equation carrying the Hurst parameter $00$ and $0
description: 26 pages, no figures. Subsections 3.1 and 4.3. were slightly reformulated during the revision of the manuscript
Taxes on U.S. Agricultural Real Estate, 1980-1991, and Methods of Estimation
Creators: name: DeBraal, J. Peter
name: DeBraal, J. Peter
Publisher: name: Unknown
Year: 1993
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Farm Management
subject: Land Economics/Use
subject: Research Methods/ Statistical Methods
subject: Agricultural land
subject: farmland
subject: real estate taxes
subject: property taxes

description: This bulletin provides State-level estimates of agricultural real estate taxes since 1890. Estimates include average taxes per acre for 1890-1991, and total taxes and taxes per $100 of full market value for 1909-91. The bulletin also explains the methods used by the U.S. Department of Agriculture for obtainil11g and estimating the data.
Calculation of $K\toππ$ decay amplitudes from $K\toπ$ matrix elements in quenched domain-wall QCD
Creators: name: PACS Collaboration
name: Aoki, S.
name: Aoki, Y.
name: Burkhalter, R.
name: Ejiri, S.
name: Fukugita, M.
name: Hashimoto, S.
name: Ishizuka, N.
name: Iwasaki, Y.
name: Izubuchi, T.
name: Kanaya, K.
name: Kaneko, T.
name: Kuramashi, Y.
name: Lesk, V.
name: Nagai, K. -I.
name: Noaki, J.
name: Okawa, M.
name: Taniguchi, Y.
name: Ukawa, A.
name: Yoshi'e, T.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We present a calculation of the $K\toππ$ decay amplitudes from the $K\toπ$ matrix elements using leading order relations derived in chiral perturbation theory. Numerical simulations are carried out in quenched QCD with the domain-wall fermion action and the renormalization group improved gluon action. Our results show that the I=2 amplitude is reasonably consistent with experiment whereas the I=0 amplitude is sizably smaller. Consequently the $ΔI=1/2$ enhancement is only half of the experimental value, and $ε'/ε$ is negative.
description: Lattice2001(hadronic matrix elements), 3pages, 6 eps figures
MOESM1 of European Medicines Agency Policy 0070: an exploratory review of data utility in clinical study reports for academic research
Creators: name: Jean-Marc Ferran
name: Nevitt, Sarah
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Pharmacology
subject: Sociology
subject: FOS: Sociology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Additional file 1: Table S1. Examples of academic work using CSRs in secondary research.
title: Sayyids and Social Stratification of Muslims in Colonial India
title: Genealogy and Narration of the Past in Amroha
titleType: Subtitle
Creators: name: Niazi, Soheb
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: Muslims
subject: Colonial India
subject: 300 Sozialwissenschaften::300 Sozialwissenschaften, Soziologie::300 Sozialwissenschaften

description: While Islamic scriptures like the Quran and Hadith are often quoted to negate the existence of social stratification among Muslims, authors of genealogical texts rely on the very same scriptures to foreground and legitimise discussions on descent and lineage. In the South Asian context, several conceptions of hierarchy as practised by Muslims in north India evolved over the course of colonial rule and were deployed interchangeably by Sayyids. These were based on notions of race, ethnicity, respectability and nobility, and occupational distinctions as well as narratives that referred to the history of early Islam. This article contributes to the study of social stratification among South Asian Muslims by exploring the evolution of Urdu tarikh (historical texts) produced by Sayyid men in the qasbah of Amroha in the Rohilkhand region of the United Provinces during the late nineteenth and early twentieth centuries. The Sayyid authors narrated the past through the medium of nasab (genealogy). While their texts place emphasis on lineage and descent to legitimise a superior social status for Sayyids, they also shed light on the changing social and material context of the local qasbah politics with the discourse on genealogy evolving into a form that engaged with social contestations.
Density-of-states picture and stability of ferromagnetism in the highly-correlated Hubbard model
Creators: name: Irkhin, V. Yu.
name: Zarubin, A. V.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The problem of stability of saturated and non-saturated ferromagnetism in the Hubbard model is considered in terms of the one-particle Green's functions. Approximations by Edwards and Hertz and some versions of the self-consistent approximations based on the 1/z-expansion are considered. The account of longitudinal fluctuations turns out to be essential for description of the non-saturated state. The corresponding pictures of density of states are obtained. "Kondo" density-of-states singularities owing to spin-flip processes are analyzed. The critical electron concentrations for instabilities of saturated ferromagnetism and paramagnetic state are calculated for various lattices. Drawbacks of various approximations are discussed. A comparison with the results of previous works is performed.
description: 16 pages, 7 eps figures
A policy and institutional analysis of urban transport system: the case of Pakistan’s Lahore in the context of COVID-19
Creators: name: Ayaz, Quratulain
name: Abubakari, Mohammed
name: Hussain, Jawad
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Science Policy
Mental Health

description: The bicycle is recognized as a sustainable mode of transport, yet in the developing world, its use is hindered by several factors. The COVID-19 pandemic, with its emphasis on isolation, created a changed travel pattern and thus an experimental environment for bicycling. This study examines Lahore, Pakistan, to evaluate bicycle promotion during and beyond the pandemic. It assesses policy frameworks, institutional implementation capacity, and the perception of cycling infrastructure and regulations based on the user feedback. Lahore, a major Pakistani city with significant development and capacity, has faced severe smog and poor air quality, highlighting the need for environmentally friendly transport. The study reveals an increase in bicycle use during COVID-19 restrictions, with over 96% of the respondents noting this rise. Many tried bicycling for the first time due to reduced traffic. However, post-restrictions opinions varied on whether the trend persisted. Better road infrastructure was found to corelate positively with the bicycling trend. Studies identified traffic lawlessness, high motorization, lack of infrastructure, smog, and harsh weather as major barriers. Despite the existence of civil society groups promoting bicycling, their efforts are hindered by lack of participation in policy and decision making. The study calls for addressing policy and institutional bottlenecks to promote bicycling in Lahore, with broader implications for Pakistan and other developing countries. Improved coordination among institutions and inclusion of user perspectives are crucial for creating a more bicycle friendly system.
The far-infrared energy distributions of Seyfert and starburst galaxies in the Local Universe: ISO photometry of the 12 micron active galaxy sample
Creators: name: Spinoglio, Luigi
name: Andreani, Paola
name: Malkan, Matthew A.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: New far-infrared photometry with ISOPHOT, onboard the Infrared Space Observatory, is presented for 58 galaxies with homogeneous published data for another 32 galaxies all belonging to the 12 micron galaxy sample. In total 29 Seyfert 1's, 35 Seyfert 2's and 12 starburst galaxies, about half of the 12 micron active galaxy sample, plus 14 normal galaxies for comparison. The ISO and the IRAS data are used to define color-color diagrams and spectral energy distributions (SED). Thermal dust emission at two temperatures (one cold at 15-30K and one warm at 50-70K) can fit the 60-200 micron SED, with a dust emissivity law proportional to the inverse square of the wavelength. Seyfert 1's and Seyfert 2's are indistinguishable longward of 100 micron, while, as already seen by IRAS, the former have flatter SEDs shortward of 60 micron. A mild anti-correlation is found between the [200 - 100] color and the "60 micron excess". We infer that this is due to the fact that galaxies with a strong starburst component, and thus a strong 60 micron flux, have a steeper far-infrared turnover. In non-Seyfert galaxies, increasing the luminosity corresponds to increasing the star formation rate, that enhances the 25 and 60 micron emission. This shifts the peak emission from around 150 micron in the most quiescent spirals to shorter than 60 micron in the strongest starburst galaxies.
description: Accepted for publication in The Astrophysical Journal AASTeX preprint with 49 pages and 20 figures Also available at http://orion.ifsi.rm.cnr.it/publ.html
A General Legal Right to Conscientious Exemption: Beyond Religious Privilege
Creators: name: Adenitire, John
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: conscience
religion
human right
discrimination
conscientious objection
conscientious exemption
law

description: The thesis shows that there is a general legal right to exemption for conscientious objectors in the US, Canada and UK. It shows that it is a limited right: exemptions may be lawfully denied to protect the rights of others or important public interests. The thesis then investigates whether such a legal right is exclusively reserved for religious believers. The thesis shows that it is not: it is available to those that object on the basis of conscience, irrespective of whether their conscience is motivated by religious or non-religious beliefs. The thesis concludes by defending the existence of this general right by appealing to liberal values.
description: AHRC DTP
Short-distance constraints on hadronic light-by-light scattering in the anomalous magnetic moment of the muon
Creators: name: Colangelo, Gilberto
name: Hagelstein, Franziska
name: Hoferichter, Martin
name: Laub, Laetitia
name: Stoffer, Peter
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: High Energy Physics - Lattice (hep-lat)
subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: A key ingredient in the evaluation of hadronic light-by-light (HLbL) scattering in the anomalous magnetic moment of the muon $(g-2)_μ$ concerns short-distance constraints (SDCs) that follow from QCD by means of the operator product expansion. Here we concentrate on the most important such constraint, in the longitudinal amplitudes, and show that it can be implemented efficiently in terms of a Regge sum over excited pseudoscalar states, constrained by phenomenological input on masses, two-photon couplings, as well as SDCs on HLbL scattering and the pseudoscalar transition form factors (TFFs). Our estimate of the effect of the longitudinal SDCs on the HLbL contribution is: $Δa_μ^\text{LSDC}=13(6)\times 10^{-11}$. This is significantly smaller than previous estimates, which mostly relied on an ad-hoc modification of the pseudoscalar poles and led to up to a $40\%$ increase with respect to the nominal pseudoscalar-pole contributions, when evaluated with modern input for the relevant TFFs. We also comment on the status of the transversal SDCs and, by matching to perturbative QCD, argue that the corresponding correction will be significantly smaller than its longitudinal counterpart.
description: 7 pages, 2 figures; journal version
MOESM5 of Spatiotemporal spread of sarcoptic mange in the red fox (Vulpes vulpes) in Switzerland over more than 60 years: lessons learnt from comparative analysis of multiple surveillance tools
Creators: name: Pisano, Simone
name: Zimmermann, Fridolin
name: Rossi, Luca
name: Simon Capt
name: Akdesir, Ezgi
name: BĂźrki, Roland
name: Kunz, Florin
name: Origgi, Francesco
name: Ryser-Degiorgis, Marie-Pierre
Publisher: name: figshare
Year: 2019
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 5: Table S8. Cantonal and national hunting statistics before, during and after the rabies epidemics.
Integral equation for spin dependent unintegrated parton distributions incorporating double ln^2(1/x) effects at low x
Creators: name: Kwiecinski, Jan
name: Maul, Martin
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper we derive an integral equation for the evolution of unintegrated (longitudinally) polarized quark and gluon parton distributions. The conventional CCFM framework is extended at small x in order to incorporate the QCD expectations concerning the double ln^2(1/x) resummation at low x for the integrated distributions. Complete Altarelli-Parisi splitting functions are included, that makes the formalism compatible with the LO Altarelli-Parisi evolution at large and moderately small values of x. The obtained modified polarized CCFM equation is shown to be partially diagonalized by the Fourier-Bessel transform. Results of the numerical solution for this modified CCFM equation for the non-singlet quark distributions are presented.
description: 24 pages, 3 figures, LaTeX, some discussion added, none of the results changed, version to appear in Phys. Rev. D
Symmetry breaking and skyrmionic transport in twisted bilayer graphene
Creators: name: Chatterjee, Shubhayu
name: Bultinck, Nick
name: Zaletel, Michael P.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Motivated by recent low-temperature magnetoresistance measurements in twisted bilayer graphene aligned with hexagonal Boron Nitride substrate, we perform a systematic study of possible symmetry breaking orders in this device at a filling of two electrons per Moiré unit cell. We find that the surprising non-monotonic dependence of the resistance on an out-of-plane magnetic field is difficult to reconcile with particle-hole charge carriers from the low-energy bands in symmetry broken phases. We invoke the non-zero Chern numbers of the twisted bilayer graphene flat bands to argue that skyrmion textures provide an alternative for the dominant charge carriers. Via an effective field-theory for the spin degrees of freedom, we show that the effect of spin Zeeman splitting on the skyrmion excitations provides a possible explanation for the non-monotonic magnetoresistance. We suggest several experimental tests, including the functional dependence of the activation gap on the magnetic field, for our proposed correlated insulating states at different integer fillings. We also discuss possible exotic phases and quantum phase transitions that can arise via skyrmion-pairing on doping such an insulator.
description: 13 + 15 pages, 8 + 1 figures; (v2) Expanded Sec. VI on skyrmion pairing, updated references
Defining case management and outreach: perspectives from community health workers in New Mexico
Creators: name: Perez, Mayra
name: Ceballos, Venice
name: Rubio, Nathaniel
name: Garcia, Jennifer
name: Rubi, Delfino
name: Cabrera, Alejandra
name: Milligan, Kelley
name: Kelley, Allyson
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Science Policy
Computational Biology

description: Case management (CM) is increasingly used in community settings to support individuals as they transition from one point in their lives to the next. This study sought to explore the perspectives of front-line Community Health Workers CMs working in Albuquerque, New Mexico. The objective of this study was to answer the question ‘How do CHWs define effective CM and outreach?’ A follow-up question was, ‘What are the barriers to conducting CM and outreach?’ Qualitative research methods, Critical Race Theory, and Social Work Theory guided this study. Five CHW CMs participated in a 90-minute focus group. Results present their perspectives on effective CM and outreach. Barriers include limited collaborations, excessive documentation requirements, and communication. Findings demonstrate that what constitutes effective CM and outreach is based on the program and context. Future work must focus on balancing the need for shared definitions and embracing the flexibility required for CMs working on the ground in diverse settings and populations.
Statistical Re-examination of Reported Emission Lines in the X-ray Afterglow of GRB 011211
Creators: name: Rutledge, Robert E.
name: Sako, Masao
Publisher: name: arXiv
Year: 2002
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: (abridged) A 0.2-12 keV spectrum obtained with the XMM EPIC/pn instrument of GRB 011211 was found by Reeves et al. (2002) to contain emission lines which were interpreted to be from Mg XI, Si XIV, S XVI, Ar XVIII, and Ca XX, at a lower redshift (z_{obs}=1.88) than the host galaxy (z_{host}=2.14). We examine the spectrum independently, and find that the claimed lines would not be discovered in a blind search. Specifically, Monte Carlo simulations show that they would be observed in 10% of featureless spectra with the same signal-to-noise. Imposing a model in which the two brightest lines would be Si XIV and S XVI K-alpha emission possibly velocity shifted to between z=1.88--2.40, such features would be found in between ~1.2-2.6% of observed featureless spectra. We find the detection significances to be insufficient to justify the claim of detection and the model put forth to explain them. K-alpha line complexes are also found at z=1.2 and z=2.75 of significance equal to or greater than that at z=1.88. If one adopts the z=1.88 complex as significant, one must also adopt the other two complexes to be significant. The interpretation of these data in the context of the model proposed by Reeves et al. is therefore degenerate, and cannot be resolved by these data alone.
description: 23 pages, 4 figures. MNRAS, accepted. Expanded discussion
Hadron Spectrum for Quenched Domain-Wall Fermions with DBW2 Gauge Action
Creators: name: Aoki, Yasumichi
name: collaboration, RBC
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We investigate basic physical quantities for quenched simulation with domain-wall fermions and the DBW2 gauge action. Masses and decay constant of pseudoscalar mesons are measured. Scaling properties are tested.
description: Lattice2001(spectrum), 3 pages, 5 figures
Incorporating prior knowledge into deep neural networks without handcrafted features
Creators: name: Garnelo Abellanas, Marta
Publisher: name: Imperial College London
Year: 2020

description: Deep learning (DL) is currently the largest area of research within artificial intelligence (AI). This success can largely be attributed to the data-driven nature of the DL algorithms themselves: unlike previous approaches in AI which required handcrafting and significant human intervention, DL models can be implemented and trained with little to no human involvement. The lack of handcrafting, however, can be a two-edged sword. DL algorithms are notorious for producing uninterpretable features, generalising badly to new tasks and relying on extraordinarily large datasets for training. In this thesis, on the assumption that these shortcomings are symptoms of the under-constrained training setup of deep networks, we address the question of how to incorporate knowledge into DL algorithms without reverting to complete handcrafting in order to train more data efficient algorithms. % In this thesis we consider different alternatives to this problem. We start by motivating this line of work with an example of a DL architecture which, inspired by symbolic AI, aims at extracting symbols from a simple environment and using those for quickly learning downstream tasks. Our proof-of-concept model shows that it is possible to address some of the data efficiency issues as well as obtaining more interpretable representations by reasoning at this higher level of abstraction. Our second approach for data-efficiency is based on pre-training: the idea is to pre-train some parts of the DL network on a different, but related, task to first learn useful feature extractors. For our experiments we pre-train the encoder of a reinforcement learning agent on a 3D scene prediction task and then use the features produced by the encoder to train a simulated robot arm on a reaching task. Crucially, unlike previous approaches that could only learn from fixed view-points, we are able to train an agent using observations captured from randomly changing positions around the robot arm, without having to train a separate policy for each observation position. Lastly, we focus on how to build in prior knowledge through the choice of dataset. To this end, instead of training DL models on a single dataset, we train them on a distribution over datasets that captures the space of tasks we are interested in. This training regime produces models that can flexibly adapt to any dataset within the distribution at test time. Crucially they only need a small number of observations in order to adapt their predictions, thus addressing the data-efficiency challenge at test time. We call this family of meta-learning models for few-shot prediction Neural Processes (NPs). In addition to successfully learning how to carry out few-shot regression and classification, NPs produce uncertainty estimates and can generate coherent samples at arbitrary resolutions.
Quantum noise in current biased Josephson junction
Creators: name: Levinson, Y.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Quantum fluctuations in a current biased Josephson junction, described in terms of the RCSJ-model, are considered. The fluctuations of the voltage and phase across the junction are assumed to be initiated by equilibrium current fluctuations in the shunting resistor. This corresponds to low enough temperatures, when fluctuations of the normal current in the junction itself can be neglected. We used the quantum Langevin equation in terms of random variables related to the limit cycle of the nonlinear Josephson oscillator. This allows to go beyond the perturbation theory and calculate the widths of the Josephson radiation lines.
Additional file 1 of Multifunctional AIE iridium (III) photosensitizer nanoparticles for two-photon-activated imaging and mitochondria targeting photodynamic therapy
Creators: name: Cai, Xuzi
name: Wang, Kang-Nan
name: Ma, Wen
name: Yang, Yuanyuan
name: Chen, Gui
name: Fu, Huijiao
name: Cui, Chunhui
name: Yu, Zhiqiang
name: Wang, Xuefeng
Publisher: name: figshare
Year: 2021
Subjects: Biochemistry
Space Science
Medicine
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Cancer

description: Additional file 1. Additional information includes additional figures.