cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Soothing Satire
Creators: name: McEvoy-Halston, Patrick
Publisher: name: Humanities Commons
Year: 2006
Subjects: subject: American literature
subject: Twentieth century
subject: Canadian literature
subject: Generation X

description: Explores Douglas Coupland's "Generation X" as almost a Gen Xer's "version of John Updike's Couples"; that is, as, a place where, like Updike's book, friends create a community isolated only to themselves. Though unlike Updike's work, where -- considering the time it was written in, the '70s, where a generation succeeded in overtly contesting and bypassing their parents --  Coupland's ideal community is cloaked to appear its opposite, so mutual nurturance, challenge, narcissistic-in-a-good-way growth, has its full chance to incur within constituents.
Foodborne Transmission of Bovine Spongiform Encephalopathy to Nonhuman Primates
Creators: name: Holznagel, Edgar
name: Yutzy, Barbara
name: Schulz-Schaeffer, Walter
name: Kruip, Carina
name: Hahmann, Uwe
name: Bierke, Pär
name: Torres, Juan-Maria
name: Kim, Yong-Sun
name: Thomzig, Achim
name: Beekes, Michael
name: Hunsmann, Gerhard
name: Löwer, Johannes
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2013
Subjects: subject: Animals
subject: Humans
subject: Amino Acid Sequence
subject: Molecular Sequence Data
subject: Sequence Alignment
subject: Cattle
subject: Disease Models Animal
subject: Brain/pathology
subject: Creutzfeldt-Jakob Syndrome/diagnosis
subject: Creutzfeldt-Jakob Syndrome/metabolism
subject: Creutzfeldt-Jakob Syndrome/physiopathology
subject: Creutzfeldt-Jakob Syndrome/transmission
subject: Encephalopathy Bovine Spongiform/diagnosis
subject: Encephalopathy Bovine Spongiform/metabolism
subject: Encephalopathy Bovine Spongiform/physiopathology
subject: Encephalopathy Bovine Spongiform/transmission
subject: Foodborne Diseases/diagnosis
subject: Foodborne Diseases/metabolism
subject: Foodborne Diseases/physiopathology
subject: Infectious Disease Incubation Period
subject: Macaca fascicularis
subject: Meat/poisoning
subject: PrPSc Proteins/chemistry
subject: PrPSc Proteins/genetics
subject: PrPSc Proteins/isolation & purification
subject: 610 Medizin

description: Risk for human exposure to bovine spongiform encephalopathy (BSE)–inducing agent was estimated in a nonhuman primate model. To determine attack rates, incubation times, and molecular signatures, we orally exposed 18 macaques to 1 high dose of brain material from cattle with BSE. Several macaques were euthanized at regular intervals starting at 1 year postinoculation, and others were observed until clinical signs developed. Among those who received ≥5 g BSE-inducing agent, attack rates were 100% and prions could be detected in peripheral tissues from 1 year postinoculation onward. The overall median incubation time was 4.6 years (3.7–5.3). However, for 3 macaques orally exposed on multiple occasions, incubation periods were at least 7–10 years. Before clinical signs were noted, we detected a non-type 2B signature, indicating the existence of atypical prion protein during the incubation period. This finding could affect diagnosis of variant Creutzfeldt-Jakob disease in humans and might be relevant for retrospective studies of positive tonsillectomy or appendectomy specimens because time of infection is unknown.
sj-pdf-1-jsm-10.1177_10996362211020420 - Supplemental material for Bending fatigue of single-wall and double-wall corrugated paperboards under sinusoidal and random loads
Creators: name: Wang, Zhi-Wei
name: Lai, Yang-Zhou
name: Wang, Li-Jun
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 91299 Materials Engineering not elsewhere classified
subject: FOS: Materials engineering

description: Supplemental material, sj-pdf-1-jsm-10.1177_10996362211020420 for Bending fatigue of single-wall and double-wall corrugated paperboards under sinusoidal and random loads by Zhi-Wei Wang, Yang-Zhou Lai and Li-Jun Wang: on behalf of the TLC Study Group in Journal of Sandwich Structures and Materials
sj-pdf-2-mde-10.1177_23821205211030176 – Supplemental material for The Development of Empathy and Associated Factors during Medical Education: A Longitudinal Study
Creators: name: Kötter, Thomas
name: Kiehn, Leevke
name: Obst, Katrin Ulrike
name: Voltmer, Edgar
Publisher: name: SAGE Journals
Year: 2021
Subjects: Education

description: Supplemental material, sj-pdf-2-mde-10.1177_23821205211030176 for The Development of Empathy and Associated Factors during Medical Education: A Longitudinal Study by Thomas Kötter, Leevke Kiehn, Katrin Ulrike Obst and Edgar Voltmer in Journal of Medical Education and Curricular Development
Soothing Satire
Creators: name: McEvoy-Halston, Patrick
Publisher: name: unknown
Year: 2006
Subjects: subject: Twentieth century
subject: Canadian literature
subject: Generation X
subject: American literature

description: Explores Douglas Coupland's "Generation X" as almost a Gen Xer's "version of John Updike's Couples"; that is, as, a place where, like Updike's book, friends create a community isolated only to themselves. Though unlike Updike's work, where -- considering the time it was written in, the '70s, where a generation succeeded in overtly contesting and bypassing their parents -- Coupland's ideal community is cloaked to appear its opposite, so mutual nurturance, challenge, narcissistic-in-a-good-way growth, has its full chance to incur within constituents.
Daten zur Palliativversorgung in Deutschland
Creators: name: Prütz, Franziska
name: Saß, Anke-Christine
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2016
Subjects: subject: Daten
subject: Palliativversorgung
subject: Palliativmedizin
subject: Sterben
subject: Hospiz
subject: 610 Medizin

description: Palliativversorgung steht zunehmend im Blickfeld von Politik und Öffentlichkeit. Dabei wird deutlich, dass der Bedarf an palliativen Angeboten hoch und noch keine flächendeckende Versorgung erreicht ist, auch wenn Angebot und Inanspruchnahme der Palliativversorgung in den letzten Jahren stark angestiegen sind. Um die Entwicklung in Deutschland darzustellen, vorhandene Versorgungslücken aufzuzeigen und die Auswirkungen politischer Maßnahmen zu beurteilen, sind belastbare und kontinuierlich zur Verfügung stehende Daten unabdingbar. Im vorliegenden Beitrag werden die öffentlich zugänglichen Datenquellen zur Palliativversorgung in Deutschland systematisch dargestellt, ihre Potenziale und Limitationen aufgezeigt. Dabei zeigt sich, dass vor allem Daten zum Angebot an Palliativversorgung verfügbar sind. Daten zur Inanspruchnahme beschränken sich im Wesentlichen auf die stationäre Versorgung und die spezialisierte ambulante Palliativversorgung (SAPV). Um die Datenlücken zu schließen, wäre u. a. eine regelmäßige Auswertung von Routinedaten der Krankenkassen und Kassenärztlichen Vereinigungen wünschenswert. Ebenfalls interessant wäre ein Monitoring im Hinblick auf die soziodemografischen Merkmale derjenigen, die eine Palliativversorgung in Anspruch nehmen. Einen wichtigen Indikator stellen auch die Sterbeorte dar. An deren Abgleich mit den Wünschen der Bevölkerung lässt sich ablesen, dass weiterhin die Notwendigkeit besteht, ambulante Strukturen der palliativen Versorgung zu stärken.
The relationship between glucose intolerance status and risk of hospitalization during two decades of follow-up: Tehran lipid and glucose study
Creators: name: Rasooli, Rahele
name: Ramezankhani, Azra
name: Khalili, Davood
name: Tohidi, Maryam
name: Hasheminia, Mitra
name: Azizi, Fereidoun
name: Hadaegh, Farzad
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Medicine
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Virology

description: To assess the relationship between glucose intolerance statuses at baseline defined as normal glucose tolerance (NGT), pre-diabetes, newly diagnosed (NDM) and known diabetes mellitus (KDM) and all-cause hospitalization among Iranian men and women during 20 years of follow-up. This study included 8,014 individuals (3,836 men) ≥30 years from the cohort of Tehran Lipid and Glucose Study. Incidence rate ratios (IRRs) and (95% confidence interval (95% CI) for three groups of pre-diabetes, NDM and KDM was estimated using the Negative Binomial regression model, considering NGT group as reference group. Regression models were adjusted for age, body mass index, hypertension, chronic kidney disease, and cardiovascular disease (CVD). Among men, compared with NGT group, those with pre-diabetes, NDM and KDM had higher incidence rate for hospitalization, with IRRs (95% CI) of 1.08 (0.96–1.20), 1.38 (1.20–1.57) and 1.96 (1.66–2.26), respectively, after adjusting for confounders. The corresponding values were 1.07 (0.96–1.17), 1.40 (1.21–1.59) and 2.07 (1.72–2.42) for women. Men with diabetes, generally had a higher rate of hospitalization for CVD rather than their female counterparts (IRRs: 1.46; 1.17–1.74). In patients with diabetes, the most common causes of hospitalization were macrovascular complications (i.e. coronary heart disease and stroke). Moreover, among the individuals with diabetes, those with poor glycaemic control (fasting plasma glucose (FPG) >10 mmol/l) had 39% higher rate of hospitalization than those with fair glycaemic control (FPG <10 mmol/l) (1.39; 1.12–1.65), adjusted for confounders. Pre-diabetes, NDM, and KDM were associated with increased hospitalization rates during long-term follow-up. Interventions such as lifestyle modification or pharmacological therapies aiming to slow down the pre-diabetes and fair control of diabetes might potentially decrease the rate of hospitalization.Key messagesNDM and KDM status both increased rate of all-cause hospitalization.CVD and T2DM complication were the most common cause of hospitalization among patients with diabetes.Hospitalization due to recurrent CHD was significantly higher in men with diabetes than their female counterparts. NDM and KDM status both increased rate of all-cause hospitalization. CVD and T2DM complication were the most common cause of hospitalization among patients with diabetes. Hospitalization due to recurrent CHD was significantly higher in men with diabetes than their female counterparts.
Indigenous house mice dominate small mammal communities in northern Afghan military bases
Creators: name: Gertler, Christoph
name: Schlegel, Mathias
name: Linnenbrink, Miriam
name: Hutterer, Rainer
name: König, Patricia
name: Ehlers, Bernhard
name: Fischer, Kerstin
name: Ryll, René
name: Lewitzki, Jens
name: Sauer, Sabine
name: Baumann, Kathrin
name: Breithaupt, Angele
name: Faulde, Michael
name: Teifke, Jens P.
name: Tautz, Diethard
name: Ulrich, Rainer G.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2017
Subjects: subject: Phylogeography
subject: Public health
subject: Military bases
subject: Rodent
subject: Shrew
subject: Mus musculus
subject: Viruses
subject: Afghanistan
subject: ISAF
subject: One health
subject: Invasive species
subject: 610 Medizin

description: Background: Small mammals are important reservoirs for pathogens in military conflicts and peacekeeping operations all over the world. This study investigates the rodent communities in three military bases in Northern Afghanistan. Small mammals were collected in this conflict zone as part of Army pest control measures from 2009 to 2012 and identified phenotypically as well as by molecular biological methods. Results: The analysis of the collected small mammals showed that their communities are heavily dominated by the house mouse Mus musculus and to a lesser extent Cricetulus migratorius and Meriones libycus. The origin of M. musculus specimens was analyzed by DNA sequencing of the mitochondrial cytochrome b gene and D-loop sequences. All animals tested belonged to the Mus musculus musculus subspecies indigenous to Afghanistan. The results were supported by detection of two nucleotide exchanges in the DNA polymerase gene of Mus musculus Rhadinovirus 1 (MmusRHV1), a herpesvirus, which is specific for all gene sequences from Afghan house mice, but absent in the MmusRHV1 sequences of German and British house mice. Studies of astrovirus RNA polymerase gene sequences did not yield sufficient resolution power for a similarly conclusive result. Conclusions: House mouse populations in military camps in Northern Afghanistan are indigenous and have not been imported from Europe. Nucleotide sequence polymorphisms in MmusRHV1 DNA polymerase gene might be used as an additional phylogeographic marker for house mice.
Additional file 4 of Effect of COVID-19 on antenatal care: experiences of medical professionals in the Netherlands
Creators: name: Gamberini, Carlotta
name: Angeli, Federica
name: Knight, Lucia
name: Zaami, Mariama
name: Al-Nasiry, Salwan
name: Ambrosino, Elena
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 4. Informed Consent Form. Informed consent form that was used in the project.
Seasonal recurrence of cowpox virus outbreaks in captive cheetahs (Acinonyx jubatus)
Creators: name: Stagegaard, Julia
name: Kurth, Andreas
name: Stern, Daniel
name: Dabrowski, Piotr Wojciech
name: Pocknell, Ann
name: Nitsche, Andreas
name: Schrick, Livia
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2017
Subjects: subject: 610 Medizin

description: Cowpox virus infections in captive cheetahs (Acinonyx jubatus) with high morbidity and mortality have already been reported in the UK and Russia in the 1970s. However, most of the reported cases have been singular events. Here, we report a total of five cowpox virus outbreaks in cheetahs in the same safari park in Denmark between 2010 and 2014. Nine cheetahs showed varying severity of clinical disease; two of them died (22%). All episodes occurred between August and October of the respective year. No other carnivores kept at the same institution nor the keepers taking care of the animals were clinically affected. The clinical picture of cowpox was confirmed by extensive laboratory investigations including histopathological and molecular analyses as well as cell culture isolation of a cowpox virus. High anti-orthopoxvirus antibody titers were detected in all 9 diseased cheetahs compared to seven contact cheetahs without clinical signs and 13 cheetahs not in direct contact. Additionally, whole genome sequencing from one sample of each cluster with subsequent phylogenetic analysis showed that the viruses from different outbreaks have individual sequences but clearly form a clade distinct from other cowpox viruses. However, the intra-clade distances are still larger than those usually observed within clades of one event. These findings indicate multiple and separate introductions of cowpox virus, probably from wild rodent populations, where the virus keeps circulating naturally and is only sporadically introduced into the cheetahs. Sero-positivity of voles (Arvicola amphibious) caught in zoo grounds strengthens this hypothesis. As a consequence, recommendations are given for medical and physical management of diseased cheetahs, for hygienic measures as well as for pre-shipment isolation before cheetah export from zoo grounds.
The Lord of the Rings: the anti-adventure
Creators: name: McEvoy-Halston, Patrick
Publisher: name: unknown
Year: 2017
Subjects: subject: Psychoanalysis and literature
subject: Criticism--Psychological aspects
subject: Fantasy literature
subject: Affect (Psychology)

description: Argues that J.R.R. Tolkien's "The Lord of the Rings" is an adventure in reverse, an "argument" for "your" regression. Rather than play with your ability to maybe succeed in threatening environments, it confirms your worst suspicions about yourself, lending you in mood to cling to others in a master-slave relationship, so long as they'll agree to protect you. First of four essays on this subject, in regards to Tolkien's masterpiece, with this essay making the overarching argument concerning the whole series, and the others involving themselves in the dynamics between characters vis-a-vis one another in the text, and the reader with each of them, as well as the text itself, as they exist particular to a particular volume of the series. The readers' identification with the hobbits is basically assumed. They are "show" of our worst suspicions of ourselves, a "test" of them.
Computer Vision Approach for Estimating Human Health Parameters
Creators: name: Gupta, Mayank
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Human-computer interaction

description: Measurement of vital cardiovascular health attributes, e.g., pulse rate variability, and estimation of exertion level of a person can help in diagnosing potential cardiovascular diseases, musculoskeletal injuries and thus monitoring an individual's well-being. Cumulative exposure to repetitive and forceful activities may lead to musculoskeletal injuries which not only reduce workers' efficiency and productivity, but also affect their quality of life. Existing techniques for such measurements pose a great challenge as they are either intrusive, interfere with human-machine interface, and/or subjective in the nature, thus are not scalable. Non-contact methods to measure these metrics can eliminate the need for specialized piece of equipment and manual measurements. Non-contact methods can have additional advantages since they are potentially scalable, portable, can be used for continuous measurements, and can be used on patients and workers with varying levels of dexterity and independence, from people with physical impairments, shop-floor workers to infants. In this work, we use face videos and the photoplethysmography (PPG) signals to extract relevant features and build a regression model that can predict pulse rate, and pulse rate variability, and a classifi cation model that can predict force exertion levels of 0%, 50%, and 100% (representing rest, moderate effort, and high effort), thus providing a non-intrusive and scalable approach. Efficient feature extraction has resulted in high accuracy for both the models.
The Lord of the Rings: the anti-adventure
Creators: name: McEvoy-Halston, Patrick
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Fantasy literature
subject: Criticism--Psychological aspects
subject: Psychoanalysis and literature
subject: Affect (Psychology)

description: Argues that J.R.R. Tolkien's "The Lord of the Rings" is an adventure in reverse, an "argument" for "your" regression. Rather than play with your ability to maybe succeed in threatening environments, it confirms your worst suspicions about yourself, lending you in mood to cling to others in a master-slave relationship, so long as they'll agree to protect you. First of four essays on this subject, in regards to Tolkien's masterpiece, with this essay making the overarching argument concerning the whole series, and the others involving themselves in the dynamics between characters vis-a-vis one another in the text, and the reader with each of them, as well as the text itself, as they exist particular to a particular volume of the series. The readers' identification with the hobbits is basically assumed. They are "show" of our worst suspicions of ourselves, a "test" of them.
Flowfield Characterization of the Boeing/AFOSR Mach-6 Quiet Tunnel
Creators: name: Gray, Kathryn A.
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Aerospace engineering not elsewhere classified

description: The quiet-flow capabilities of the Boeing/AFOSR Mach-6 Quiet Tunnel have been well established in the last decade, but a full characterization of the nozzle flow is an ongoing project. Pitot probes outfitted with Kulite pressure transducers were used to further the investigation of the tunnel's flowfield. Noise levels were calculated by integrating the power spectral densities of the measured pitot pressure fluctuations, and experiments were performed to investigate several aspects of the flow.
First, the temperature distribution along the nozzle was varied to determine if heating had an effect on the stability of the laminar nozzle-wall boundary layer. Runs made with initial stagnation pressures slightly above the maximum quiet pressure determined that additional nozzle-wall heating did not have an effect on the amount of runtime which experienced quiet flow. In addition, pitot-probe measurements were taken at various locations to better determine the axial dependence of the noise levels. Experiments were also performed using pitot probes of varying forward-facing diameters to determine the effects of probe geometry on the measured fluctuations. The results were found to differ significantly from simulations and from a previous set of experimental data, but a likely cause of the discrepancies was not found. A pitot probe mounted on the base of a cone confirmed that the aft end of a model does experience quiet flow. Finally, characterization of the flowfield was attempted when the tunnel is run using helium. The measured pressures for these experiments have a significant level of uncertainty because the sensor calibration changes as helium diffuses across the diaphragm. Nevertheless, the measurements suggest that there may be periods of uniform flow, although these periods remain unstable and unsteady.
Reader's Guide to Fellowship of the Ring
Creators: name: McEvoy-Halston, Patrick
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Fantasy literature
subject: Affect (Psychology)
subject: Criticism--Psychological aspects
subject: Psychoanalysis and literature

description: Delineates how much of J.R.R. Tolkien's "Fellowship of the Ring" is about preparing Frodo especially so that if caught out alone, he'd never dare venture a decent listen to anyone who might attempt to sway him to consider the due fate for the Ring, other than according to Gandalf's specifications. Positions the text as one that bates the reader with the allure of calling authority figures to task, of possibly borrowing on their own leadership, what they themselves have thought or done, to impel fully attending to them at times, only so as to persuade them that the consequences for doing so are likely far more formidable than they could ever possibly manage. Called out like that, drawn out like that, it's a text designed to leave the reader to entwine ever-deeper within themselves a sense of severe scolding on any pleasure in acting in any personal good faith. It teaches one to be less able to see flaws in those you believe you can't live without, even when ever-more incrementally encroaching and accumulating before you. What they don't want you to see, you never will. What they expect you to do, but which arouses guilt if expressed forthright, you'll pluck out of the air and assume your own decision or choice. "Lord of the Rings" becomes a vile road, that requires an outside critic as guide, to thwart all that Tolkien and the likes of his Gandalf, would have of you.
Reader's Guide to Fellowship of the Ring
Creators: name: McEvoy-Halston, Patrick
Publisher: name: unknown
Year: 2017
Subjects: subject: Psychoanalysis and literature
subject: Criticism--Psychological aspects
subject: Fantasy literature
subject: Affect (Psychology)

description: Delineates how much of J.R.R. Tolkien's "Fellowship of the Ring" is about preparing Frodo especially so that if caught out alone, he'd never dare venture a decent listen to anyone who might attempt to sway him to consider the due fate for the Ring, other than according to Gandalf's specifications. Positions the text as one that bates the reader with the allure of calling authority figures to task, of possibly borrowing on their own leadership, what they themselves have thought or done, to impel fully attending to them at times, only so as to persuade them that the consequences for doing so are likely far more formidable than they could ever possibly manage. Called out like that, drawn out like that, it's a text designed to leave the reader to entwine ever-deeper within themselves a sense of severe scolding on any pleasure in acting in any personal good faith. It teaches one to be less able to see flaws in those you believe you can't live without, even when ever-more incrementally encroaching and accumulating before you. What they don't want you to see, you never will. What they expect you to do, but which arouses guilt if expressed forthright, you'll pluck out of the air and assume your own decision or choice. "Lord of the Rings" becomes a vile road, that requires an outside critic as guide, to thwart all that Tolkien and the likes of his Gandalf, would have of you.
sj-pdf-1-cmp-10.1177_07388942211024956 – Supplemental material for Economic crises, civilian mobilization, and repression in developing states
Creators: name: Koren, Ore
name: Mukherjee, Bumba
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 220104 Human Rights and Justice Issues
subject: FOS: Philosophy, ethics and religion
subject: 160607 International Relations
subject: FOS: Political science

description: Supplemental material, sj-pdf-1-cmp-10.1177_07388942211024956 for Economic crises, civilian mobilization, and repression in developing states by Ore Koren and Bumba Mukherjee in Conflict Management and Peace Science
A Reader's Guide to the Two Towers
Creators: name: McEvoy-Halston, Patrick
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Affect (Psychology)
subject: Fantasy literature

description: This essay serves as a guardian, as a true friend of the reader, encouraging them to recognize that if they identify with the hobbits in this book, to be wary of the text trains the reader to become someone who would mistake their actual proud moments of self-decision, self-realization... of bravery, of the genuine kind, for something evil or bad, and mistake the text's inscriber -- the author -- as someone who actually isn't mostly afraid to see these traits manifest in the reader, while of course always pretending to himself the very opposite. The essay, as guardian of the reader, doesn't confront the reader with this, but nevertheless still basically presumes that the reader already has a built-in inclination to "be brave" in ways that don't arose their internal censors, internal censors already built-in to their brain to deter them away from ways of thinking, overt "actions," that would arose threatens of ferocious parental attack or full-out casting off; abandonment. So the true danger of the book is actually not really the way it TRAINS the reader, but the way it reinforces aspects of their world outlook that already malformed, and need, rather, the touch of true guardians, true friends, to learn to snap out of it. If the text itself doesn't provide it, then the essay implies that text plus critic, text plus GUARDIAN, be thought of as the REQUIRED minimum for much textual contact, textual involvement, to be possibly presumed to be nourishing; promote emotional evolution.
A Reader's Guide to the Two Towers
Creators: name: McEvoy-Halston, Patrick
Publisher: name: unknown
Year: 2017
Subjects: subject: Affect (Psychology)
subject: Fantasy literature

description: This essay serves as a guardian, as a true friend of the reader, encouraging them to recognize that if they identify with the hobbits in this book, to be wary of the text trains the reader to become someone who would mistake their actual proud moments of self-decision, self-realization... of bravery, of the genuine kind, for something evil or bad, and mistake the text's inscriber -- the author -- as someone who actually isn't mostly afraid to see these traits manifest in the reader, while of course always pretending to himself the very opposite. The essay, as guardian of the reader, doesn't confront the reader with this, but nevertheless still basically presumes that the reader already has a built-in inclination to "be brave" in ways that don't arose their internal censors, internal censors already built-in to their brain to deter them away from ways of thinking, overt "actions," that would arose threatens of ferocious parental attack or full-out casting off; abandonment. So the true danger of the book is actually not really the way it TRAINS the reader, but the way it reinforces aspects of their world outlook that already malformed, and need, rather, the touch of true guardians, true friends, to learn to snap out of it. If the text itself doesn't provide it, then the essay implies that text plus critic, text plus GUARDIAN, be thought of as the REQUIRED minimum for much textual contact, textual involvement, to be possibly presumed to be nourishing; promote emotional evolution.
Additional file 1 of Integrating genomics and transcriptomics to identify candidate genes for high egg production in Wulong geese (Anser cygnoides orientalis)
Creators: name: Liu, Jingjing
name: Xiao, Yu
name: Ren, Pengwei
name: Zhang, Shuer
name: Liu, Yang
name: Zhu, Mingxia
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 1
Statistical inference of time-dependent data
Creators: name: Gundimeda, Suhas
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Operations research

description: Probabilistic graphical modeling is a framework which can be used to succinctly
represent multivariate probability distributions of time series in terms of each time
series’s dependence on others. In general, it is computationally prohibitive to sta-
tistically infer an arbitrary model from data. However, if we constrain the model to
have a tree topology, the corresponding learning algorithms become tractable. The
expressive power of tree-structured distributions are low, since only n − 1 dependen-
cies are explicitly encoded for an n node tree. One way to improve the expressive
power of tree models is to combine many of them in a mixture model. This work
presents and uses simulations to validate extensions of the standard mixtures of trees
model for i.i.d data to the setting of time series data. We also consider the setting
where the tree mixture itself forms a hidden Markov chain, which could be better
suited for approximating time-varying seasonal data in the real world. Both of these
are evaluated on artificial data sets.
Décentralisation financière et dépenses locales dans les collectivités territoriales au Bénin : une approche basée sur le concept d'efficacité
Creators: name: CHABI, Adéyèmi Elie
name: ZANNOU, Missimahu Oscar Rétis
Publisher: name: Zenodo
Year: 2024
Subjects: Recettes propres ; dépenses locales ; collectivités territoriales ; scores d'efficacité ; mobilisation.

description: Ce papier examine l’effet de l’efficacité de la mobilisation des recettes propres sur les dépenses locales dans les collectivités territoriales du Bénin. Pour atteindre cet objectif, nous avons fait recours dans une première approche au programme DEAP (Data Envelopment Analysis Program) pour estimer les scores d’efficacité. Par suite, nous avons à l’aide de la régression OLS estimé l’effet de l’efficacité sur les dépenses locales à partir des données de panel de soixante-quinze communes sur la période 2008-2016. Les résultats indiquent que suite à l’augmentation d’un point de l’efficacité les dépenses locales diminuent de 0,004%. Lorsque les recettes fiscales, les recettes non fiscales, les recettes partagées, les transferts de fonctionnement, les recettes d’investissement et la taille de la population varient de 1%, les dépenses locales varient de 0,19% ; 0,182% ; 0,102% ; 0,110% ; 0,366% et 0,506%. Les communes du Bénin doivent développer davantage des stratégies visant l’amélioration des recettes propres et des recettes d’investissement qui ont une importante influence afin de soutenir les dépenses locales.
Additional file 4 of Three complete chloroplast genomes from two north American Rhus species and phylogenomics of Anacardiaceae
Creators: name: Huang, Lan
name: Xu, Yujie
name: Valcárcel, Virginia
name: Lutz, Sue
name: Wen, Jun
name: Ren, Zhumei
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 4: Table S1 Introns and exons of protein coding genes of three Rhus chloroplast genomes
The (True) Lord of the Rings
Creators: name: McEvoy-Halston, Patrick
Publisher: name: unknown
Year: 2017
Subjects: subject: Psychoanalysis and literature
subject: Affect (Psychology)
subject: Fantasy literature

description: The critic, as guide, is here in the penultimate of a four-part series on "Lord of the Rings," suggested to be, if not Sarumon himself (Sarumon's voice is used), certainly someone who could readily imagine him as someone who could have been presented in the text as a flat-out ally, if he himself wasn't relegated to being the reader's guardian and was actually the text's inscriber. The essay confronts the reader with the possibility that the text argues for one esteeming one's possible regression, and for only ostensibly understanding it as adventurous growth; for not really being able to recognize one's self-growth at all, but really only to take pleasure in others' mistaking you for having changed, having matured, having developed, requiring your thereafter necessitating the company of fools in order to buttress one's self-esteem. Confronts the reader with the fact that the hobbits they are leant in the text to identify with, function essentially as the Fellowship's toilet, a place in which to project and deposit all their own insecurities. As such, they were functionally useful, actually ESSENTIAL, for the mission, for the group, but they are denied understanding this about themselves -- which however disagreeable a reality, might nevertheless have leant some genuine self-pride: without "you," Evil would have ruled the land -- for "the great" needing to deny that they have such vast doubts and fears nested anywhere within them to source and supply their company toilet with -- and rather to esteem themselves for attributes that are either actually common or that ultimately serve to flatter someone else. Essay pronounces that the text did supply one hobbit with evidence that he was actually perhaps more remarkable than perhaps any other in Middle-earth -- Sam -- and encourages his not denying himself conscious awareness of this incontrovertible, evidence-supplied felt truth, for keeping a previous sense of personal equilibrium in place.
The (True) Lord of the Rings
Creators: name: McEvoy-Halston, Patrick
Publisher: name: Humanities Commons
Year: 2017
Subjects: subject: Affect (Psychology)
subject: Fantasy literature
subject: Psychoanalysis and literature

description: The critic, as guide, is here in the penultimate of a four-part series on "Lord of the Rings," suggested to be, if not Sarumon himself (Sarumon's voice is used), certainly someone who could readily imagine him as someone who could have been presented in the text as a flat-out ally, if he himself wasn't relegated to being the reader's guardian and was actually the text's inscriber. The essay confronts the reader with the possibility that the text argues for one esteeming one's possible regression, and for only ostensibly understanding it as adventurous growth; for not really being able to recognize one's self-growth at all, but really only to take pleasure in others' mistaking you for having changed, having matured, having developed, requiring your thereafter necessitating the company of fools in order to buttress one's self-esteem. Confronts the reader with the fact that the hobbits they are leant in the text to identify with, function essentially as the Fellowship's toilet, a place in which to project and deposit all their own insecurities. As such, they were functionally useful, actually ESSENTIAL, for the mission, for the group, but they are denied understanding this about themselves -- which however disagreeable a reality, might nevertheless have leant some genuine self-pride: without "you," Evil would have ruled the land -- for "the great" needing to deny that they have such vast doubts and fears nested anywhere within them to source and supply their company toilet with -- and rather to esteem themselves for attributes that are either actually common or that ultimately serve to flatter someone else. Essay pronounces that the text did supply one hobbit with evidence that he was actually perhaps more remarkable than perhaps any other in Middle-earth -- Sam -- and encourages his not denying himself conscious awareness of this incontrovertible, evidence-supplied felt truth, for keeping a previous sense of personal equilibrium in place.
Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010
Creators: name: Brinckmann, Sarah
name: Costa, Kelly Da
name: Gils, Marit J. Van
name: Hallengärd, David
name: Klein, Katja
name: Madeira, Luisa
name: Mainetti, Lara
name: Palma, Paolo
name: Raue, Katharina
name: Reinhart, David
name: Reudelsterz, Marc
name: Ruffin, Nicolas
name: Seifried, Janna
name: Schäfer, Katrein
name: Sheik-Khalil, Enas
name: Sköld, Annette
name: Uchtenhagen, Hannes
name: Vabret, Nicolas
name: Ziglio, Serena
name: Scarlatti, Gabriella
name: Shattock, Robin
name: Wahren, Britta
name: Gotch, Frances
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2011
Subjects: subject: Humans
subject: Animals
subject: AIDS Vaccines/immunology
subject: Clinical Trials as Topic
subject: Drug Design
subject: Anti-Infective Agents/immunology
subject: Antibody Formation/immunology
subject: 610 Medizin

description: Novel, exciting intervention strategies to prevent infection with HIV have been tested in the past year, and the field is rapidly evolving. EUROPRISE is a network of excellence sponsored by the European Commission and concerned with a wide range of activities including integrated developmental research on HIV vaccines and microbicides from discovery to early clinical trials. A central and timely theme of the network is the development of the unique concept of co-usage of vaccines and microbicides. This review, prepared by the PhD students of the network captures much of the research ongoing between the partners. The network is in its 5th year and involves over 50 institutions from 13 European countries together with 3 industrial partners; GSK, Novartis and Sanofi- Pasteur. EUROPRISE is involved in 31 separate world-wide trials of Vaccines and Microbicides including 6 in African countries (Tanzania, Mozambique, South Africa, Kenya, Malawi, Rwanda), and is directly supporting clinical trials including MABGEL, a gp140-hsp70 conjugate trial and HIVIS, vaccine trials in Europe and Africa.
Additional file 5 of Three complete chloroplast genomes from two north American Rhus species and phylogenomics of Anacardiaceae
Creators: name: Huang, Lan
name: Xu, Yujie
name: Valcárcel, Virginia
name: Lutz, Sue
name: Wen, Jun
name: Ren, Zhumei
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Supplementary Material 5: Table S2 Relative synonymous codon usage (RSCU) of chloroplast genomes of three Rhus individuals
Enhanced surveillance during a large outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany, May to June 2011
Creators: name: Wadl, Maria
name: Rieck, Thorsten
name: Nachtnebel, Matthias
name: Greutélaers, Benedikt
name: Heiden, Matthias An Der
name: Altmann, Doris
name: Hellenbrand, Wiebke
name: Faber, Mirko
name: Frank, Christina
name: Schweickert, Birgitta
name: Krause, Gérard
name: Benzler, Justus
name: Eckmanns, Tim
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2011
Subjects: subject: Disease Outbreaks
subject: Humans
subject: Female
subject: Germany/epidemiology
subject: Male
subject: Population Surveillance/methods
subject: Hemolytic-Uremic Syndrome/epidemiology
subject: Young Adult
subject: Dysentery/diagnosis
subject: Dysentery/epidemiology
subject: Dysentery/prevention & control
subject: Hemolytic-Uremic Syndrome/diagnosis
subject: Hemolytic-Uremic Syndrome/prevention & control
subject: Shiga Toxin/isolation & purification
subject: 610 Medizin

description: Germany has a well established broad statutory surveillance system for infectious diseases. In the context of the current outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany it became clear that the provisions of the routine surveillance system were not sufficient for an adequate response. This article describes the timeline and concepts of the enhanced surveillance implemented during this public health emergency.
Prevalence of Antibodies to 2009 Pandemic Influenza A (H1N1) Virus in German Adult Population in Pre- and Post-Pandemic Period
Creators: name: Dudareva, Sandra
name: Schweiger, Brunhilde
name: Thamm, Michael
name: Höhle, Michael
name: Stark, Klaus
name: Krause, Gérard
name: Buda, Silke
name: Haas, Walter
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2011
Subjects: subject: Adolescent
subject: Humans
subject: Female
subject: Male
subject: Middle Aged
subject: Adult
subject: Aged
subject: Young Adult
subject: Influenza Human/virology
subject: Antibodies Viral/blood
subject: Influenza Human/blood
subject: Influenza A Virus H1N1 Subtype/immunology
subject: Influenza Human/immunology
subject: 610 Medizin

description: Background: In order to detect levels of pre-existing cross-reactive antibodies in different age groups and to measure agespecific infection rates of the influenza A (H1N1) 2009 pandemic in Germany, we conducted a seroprevalence study based on samples from an ongoing nationwide representative health survey. Methodology/Principal Findings: We analysed 845 pre-pandemic samples collected between 25 Nov 2008 and 28 Apr 2009 and 757 post-pandemic samples collected between 12 Jan 2010 and 24 Apr 2010. Reactive antibodies against 2009 pandemic influenza A (H1N1) virus (pH1N1) were detected using a haemagglutination inhibition test (antigen A/California/ 7/2009). Proportions of samples with antibodies at titre $40 and geometric mean of the titres (GMT) were calculated and compared among 6 age groups (18–29, 30–39, 40–49, 50–59, 60–69, $70 years). The highest proportions of cross-reactive antibodies at titre $40 before the pandemic were observed among 18–29 year olds, 12.5% (95% CI 7.3–19.5%). The highest increase in seroprevalence between pre- and post-pandemic was also observed among 18–29 year olds, 29.9% (95% CI 16.7–43.2%). Effects of sampling period (pre- and post-pandemic), age, sex, and prior influenza immunization on titre were investigated with Tobit regression analysis using three birth cohorts (after 1976, between 1957 and 1976, and before 1957). The GMT increased between the pre- and post-pandemic period by a factor of 10.2 (95% CI 5.0–20.7) in the birth cohort born after 1976, 6.3 (95% CI 3.3–11.9) in those born between 1957 and 1976 and 2.4 (95% CI 1.3–4.3) in those born before 1957. Conclusions/Significance: We demonstrate that infection rates differed among age groups and that the measured prepandemic level of cross-reactive antibodies towards pH1N1 did not add information in relation to protection and prediction of the most affected age groups among adults in the pandemic.
Rotavirus genotypes co-circulating in Europe between 2006 and 2009 as determined by EuroRotaNet, a pan-European collaborative strain surveillance network
Creators: name: Iturriza-Gómara, M.
name: Dallman, T.
name: Bányai, K.
name: Böttiger, B.
name: Buesa, J.
name: Diedrich, Sabine
name: Fiore, L.
name: Johansen, K.
name: Koopmans, Marion
name: Korsun, N.
name: Koukou, D.
name: Kroneman, Annelies
name: László, B.
name: Lappalainen, M.
name: Maunula, L.
name: Marques, Andreas Mas
name: Matthinjnssens, J.
name: Midgley, S.
name: Mladenova, Z.
name: Nawaz, S.
name: Poljsak-Prijatelj, M.
name: Pothier, P.
name: Ruggeri, F. M.
name: Sanchez-Fauquier, A.
name: Steyer, A.
Publisher: name: Robert Koch-Institut
Year: 2010
Subjects: subject: Adolescent
subject: Humans
subject: Female
subject: Genotype
subject: Male
subject: Middle Aged
subject: Population Surveillance
subject: Child
subject: Adult
subject: Aged
subject: Europe/epidemiology
subject: Infant
subject: Seasons
subject: Age Factors
subject: Sex Factors
subject: Young Adult
subject: Molecular Epidemiology
subject: Child Preschool
subject: Rotavirus/genetics
subject: Rotavirus Infections/epidemiology
subject: Rotavirus Infections/virology
subject: Aged 80 and over
subject: International Cooperation
subject: Rotavirus Infections/prevention & control
subject: Rotavirus Vaccines/therapeutic use
subject: 610 Medizin

description: EuroRotaNet, a laboratory network, was established in order to determine the diversity of co-circulating rotavirus strains in Europe over three or more rotavirus seasons from 2006/2007 and currently includes 16 countries. This report highlights the tremendous diversity of rotavirus strains co-circulating in the European population during three years of surveillance since 2006/2007 and points to the possible origins of these strains including genetic reassortment and interspecies transmission. Furthermore, the ability of the network to identify strains circulating with an incidence of ≥1% allowed the identification of possible emerging strains such as G8 and G12 since the beginning of the study; analysis of recent data indicates their increased incidence. The introduction of universal rotavirus vaccination in at least two of the participating countries, and partial vaccine coverage in some others may provide data on diversity driven by vaccine introduction and possible strain replacement in Europe.
EVALUATION OF STAPHYLOCOCCUS AURUES RNPA PROTEIN AS AN ANTIBACTERIAL TARGET
Creators: name: Ha, Lisha
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Medicinal and biomolecular chemistry not elsewhere classified

description: Staphylococcus aureus (S. aureus) is a Gram-positive pathogen that causes a wide range of infections in both hospitals and communities, of which the total mortality rate is higher than AIDS, tuberculosis, and viral hepatitis combined. The drug resistant S. aureus is a member of the “ESKAPE” pathogens that require immediate and sustained actions of novel method to combat. However, the current antimicrobial development against S. aureus is in stagnation, which underscores the urgent need for novel antimicrobial scaffolds and targets. S. aureus Ribonuclease P protein (RnpA) is an essential protein that plays important roles in both tRNA maturation and mRNA degradation pathways. The goal of this research was to evaluate RnpA as an antimicrobial target using biophysical methods. The crystal structures of wild-type RnpA in three different constructs were determined, among which the tag-free RnpA construct has a structural model of 2.0 Å resolution and Rcrys/Rfree= 0.214/0.234, and its crystals are reproducible. This crystal structure of tag-free S. aureus RnpA shows a globular representation with key structural motifs, including the “RNR” Ribonuclease P RNA binding region and a substrate binding central cleft, which shares high similarity to previously solved RnpA structures from other species despite of their low sequence identity. Meanwhile, in a screen of S. aureus RnpA mutants performed by our collaborator, RnpAP89A was found lacking the mRNA degradation activity while retaining the tRNA maturation function, and causing defects in cell viability. We therefore studied this mutant using differential scanning fluorimetry, crystallography, and circular dichroism. It was shown that RnpAP89A is thermally less stable than wild-type RnpA by ~2.0 ˚C, but no secondary structural or 3D conformational differences were found between the two proteins. Although the mutant RnpAP89A requires further characterization, the results of the studies in this thesis have begun to shed light on the relatively new role of S. aureus RnpA in mRNA degradation, and will serve as useful tools in future structure-based drug discovery for multi-drug resistant S. aureus treatment.