cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Large-c superconformal torus blocks
Creators: name: Alkalaev, K. B.
name: Belavin, V. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study large-c SCFT2 on a torus specializing to one-point superblocks in the N=1 Neveu-Schwarz sector. Considering different contractions of the Neveu-Schwarz superalgebra related to the large central charge limit we explicitly calculate three superblocks, osp(1|2) global, light, and heavy-light superblocks, and show that they are related to each other. We formulate the osp(1|2) superCasimir eigenvalue equations and identify their particular solutions as the global superblocks. It is shown that the resulting differential equations are the Heun equations. We study exponentiated global superblocks arising at large conformal dimensions and demonstrate that in the leading approximation the osp(1|2) superblocks are equal to the non-supersymmetric sl(2) block.
description: 21 pages, v2: minor corrections, references added, journal version
Uncertainty and social considerations for mobile assistive robot navigation
Creators: name: Correa Villanueva, Javier
Publisher: name: Imperial College London
Year: 2014

description: An increased interest in mobile robots has been seen over the past years. The wide range of possible applications, from vacuum cleaners to assistant robots, makes such robots an interesting solution to many everyday problems. A key requirement for the mass deployment of such robots is to ensure they can safely navigate around our daily living environments. A robot colliding with or bumping into a person may be, in some contexts, unacceptable. For example, if a robot working around elderly people collides with one of them, it may cause serious injuries. This thesis explores four major components required for effective robot navigation: sensing the static environment, detection and tracking of moving people, obstacle and people avoidance with uncertainty measurement, and basic social navigation considerations. First, to guarantee adherence to basic safety constraints, sensors and algorithms required to measure the complex structure of our daily living environments are explored. Not only do the static components of the environment have to be measured, but so do any people present. A people detection and tracking algorithm, aimed for a crowded environment is proposed, thus enhancing the robot's perception capabilities. Our daily living environments present many inherent sources of uncertainty for robots, one of them arising due to the robot's inability to know people's intentions as they move. To solve this problem, a motion model that assumes unknown long-term intentions is proposed. This is used in conjunction with a novel uncertainty aware local planner to create feasible trajectories. In social situations, the presence of groups of people cannot be neglected when navigating. To avoid the robot interrupting groups of people, it first needs to be able to detect such groups. A group detector is proposed which relies on a set of gaze- and geometric-based features. Avoiding group disruption is finally incorporated into the navigation algorithm by means of taking into account the probability of disrupting a group's activities. The effectiveness of the four different components is evaluated using real world and simulated data, demonstrating the benefits for mobile robot navigation.
Ziziphus mauritiana Lam.
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Ziziphus
Ziziphus mauritiana

description: Rhamnus jujuba Linnaeus, Species Plantarum 1: 194. 1753.
"Habitat in India." RCN: 1570.
Lectotype (Johnston in Milne-Redhead & Polhill, Fl. Trop. E. Africa, Rhamnaceae: 29. 1972; Wadhwa in Dassanayake & Clayton, Revised Handb. Fl. Ceylon 10: 369. Herb. Hermann 3: 14, No. 89 (BM-000594656).
Current name: Ziziphus mauritiana Lam. (Rhamnaceae).
Note: Johnston (1972) indicated Herb. Hermann material (BM) as type. Although there is material in more than one volume, it appears to have been part of a single gathering. Consequently, this is accepted as the first typification (Art. 9.15), with the choice subsequently restricted by Wadhwa.
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 791, DOI: 10.5281/zenodo.291971
RR Lyrae stars as standard candles in the Gaia Data Release 2 Era
Creators: name: Muraveva, Tatiana
name: Delgado, Hector E.
name: Clementini, Gisella
name: Sarro, Luis M.
name: Garofalo, Alessia
Publisher: name: arXiv
Year: 2018
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present results from the analysis of 401 RR Lyrae stars (RRLs) belonging to the field of the Milky Way (MW). For a fraction of them multi-band ($V$, $K_{\rm s}$, $W1$) photometry, metal abundances, extinction values and pulsation periods are available in the literature and accurate trigonometric parallaxes measured by the Gaia mission alongside Gaia $G$-band time-series photometry have become available with the Gaia second data release (DR2) on 2018 April 25. Using a Bayesian fitting approach we derive new near-, mid-infrared period-absolute magnitude-metallicity ($PMZ$) relations and new absolute magnitude-metallicity relations in the visual ($M_V - {\rm [Fe/H]}$) and $G$ bands ($M_G - {\rm [Fe/H]}$), based on the Gaia DR2 parallaxes. We find the dependence of luminosity on metallicity to be higher than usually found in the literature, irrespective of the passband considered. Running the adopted Bayesian model on a simulated dataset we show that the high metallicity dependence is not caused by the method, but likely arises from the actual distribution of the data and the presence of a zero-point offset in the Gaia parallaxes. We infer a zero-point offset of $-0.057$ mas, with the Gaia DR2 parallaxes being systematically smaller. We find the RR Lyrae absolute magnitude in the $V$, $G$, $K_{\rm s}$ and $W1$ bands at metallicity of [Fe/H]=$-1.5$ dex and period of P = 0.5238 days, based on Gaia DR2 parallaxes to be $M_V = 0.66\pm0.06$ mag, $M_G = 0.63\pm0.08$ mag, $M_{K_{\rm s}} = -0.37\pm0.11$ mag and $M_{W1} = -0.41\pm0.11$ mag, respectively.
description: 18 pages, 21 figures, 4 tables. Accepted for publication in MNRAS
Reminiscences of Marietta Tree 1967
Publisher: name: Columbia University
Year: 2019
Subjects: Civic leaders
Diplomatic representatives
Diplomacy
Civic activism

description: Recollections of Adlai Stevenson; appointment to UN Human Rights Commission; US mission to the UN under Stevenson; Democratic Advisory Committee; Stevenson's relationship with Lyndon Johnson; 1952 campaign; press representation during the 1950's; 1956 campaign; Cuba missile crisis; NSC; Marine landing in Dominican Republic; last weeks of Stevenson's life and Stevenson funeral. Impressions of Eleanor Roosevelt, Harry S. Truman, George Ball, John F. Kennedy.
Additional file 1 of Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis
Creators: name: Lee, Ji-Hyun
name: Jung, Jae Hun
name: Kim, Jeesoo
name: Baek, Won-Ki
name: Rhee, Jinseol
name: Kim, Tae-Hwan
name: Kim, Sang-Hyon
name: Kim, Kwang Pyo
name: Son, Chang-Nam
name: Kim, Jong-Seo
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Table S1. Baseline characteristics of the first patient cohort used for the LC-MS/MS experiments and the associated western blot verification (a), and the second patient cohort used for the western blot verification (b).
Sustainability analysis of copper extraction and processing using LCA methods
Creators: name: Castro Molinaire, Julio
Publisher: name: Imperial College London
Year: 2013

description: The concept of sustainability on the one hand and the extraction and processing of primary resources on the other, at first glance, appear to be in conflict, since the production processes deplete resources that are strictly considered finite. In addition, these processes inevitably disturb the environment. This is especially true in copper production considering this is a metal with a high global demand, currently mined at increasingly low grades. Life Cycle Assessment (LCA) is an established method to assess the sustainability profile of products, processes and systems that has become important in recent years through the establishment of the ISO 14040 series of standards. Although LCA studies on mining and mineral processing systems, including copper, have been carried out since the mid- to late 1990s; these studies are limited to the ore extraction and mineral processing, not considering waste management, which is absent from all LCA based sustainability assessment of metal production systems reported in literature. In addition the low level of detail used in conventional LCA tools (not accounting for emissions at unit process level) lead to oversimplifications and underestimation of the true impacts. In this PhD research an LCA model has been developed to assess the impacts of copper mining and processing, considering the mine, mineral processing and waste disposal facilities life cycles as part of the copper production. The model is designed at unit process level and integrates the mining (open-pit and underground), mineral processing and waste management processes and accounts for emissions to the different environmental compartments (air, water, soil). The life cycle inventory (LCI) models developed are designed using specific activity data at component unit-process level together with emission factors from literature (US EPA, Australian NPI) and engineering calculations or models. The model developed uses mass balance/equilibrium calculations from intermediate products, resource consumption rates or activity levels to estimate life cycle estimates. The model functionality is illustrated using a true Chilean mine case study which was parameterised using mining, mineral processing and waste disposal facilities information for a baseline year when detailed operational data and key variables were recorded. The different LCA impact indicators estimated are carbon footprint (or global warming potential), water footprint, human toxicity, resource depletion and ecotoxicity (USEtox). Different Life Cycle Impact Assessment (LCIA) methods, chosen from the most recent and widely used LCIA methods, are utilised to compare the different methods results. Extensive Sensitivity and Monte Carlo analysis is performed to assess the uncertainty of key parameters. The response of the LCA impact indicator scores to the variation of variables such as the copper ore grade, copper recovery efficiency, average stripping ratio, electricity grid mix, are evaluated and presented.
Reminiscences of Marion L. Dawson 1970
Publisher: name: Columbia University
Year: 2019
Subjects: Veterans
Aeronautics, Military
World War, 1939-1945
Korean War, 1950-1953--Armistices
Military education

description: Education, Naval Academy, 1923-27; patrols and bandit skirmishes in Nicaragua, 1928-29; student naval aviator, Pensacola, 1929-30; early aviation assignments; parachute training school, Lakehurst, New Jersey, 1940-42; Solomon Islands, 1943-44; Naval Air Training Command, Pensacola, 1944-45; 1st Marine Aircraft Wing, China, 1946-47; air commands; Senior Member, Military Armistice Commission, Korea, 1960.
Assessment of the value of flexibility by using stochastic scheduling tool
Creators: name: Teng, Fei
Publisher: name: Imperial College London
Year: 2015

description: This thesis proposes novel analytical models for assessing the role and the value of various flexibility resources in the future low-carbon systems with high penetration of renewable energy resources. A novel stochastic scheduling model is developed, which optimises system operation by simultaneously scheduling energy production, standing/spinning reserves and inertia-dependent frequency regulation in light of uncertainties associated with wind energy production and thermal generation outages. The proposed model is shown to be particularly suitable for analysing the value of flexibility. Following this, the thesis presents an assessment of the value that energy storage may deliver to the owner in the application to energy and ancillary service markets. The results suggest that the value of energy storage is mainly driven by the temporal arbitrage opportunities created by volatility in energy prices. The value of energy storage is shown to be site-specific when there are active network constraints. A novel methodology is then proposed and applied to assess the role and the value of frequency regulation support (synthetic inertia (SI) and primary frequency response (PRF)) from wind plants (WPs). The results suggest the SI could effectively reduce the system operation cost in the system, especially with high penetration of wind generation. The analysis also demonstrates the value for WPs in providing PFR is system-specified. Combined provision of SI and PFR is required, in the case that there exists severe recovery effect associated with SI provision. This thesis also proposes a novel demand side response model (DSRM), which models and controls the recovery period during and after frequency regulation provision and thus optimally allocates multiple frequency services. The results attest the value of the DSRM compared with alternative approaches for demand response schemes. Moreover, this thesis quantifies the implications of electric vehicle deployment, heat pumps, industrial and commercial and dynamic time-of-use tariffs for the carbon emissions and renewable integration cost of the broader GB electricity system. Finally, this thesis investigates the value of enhanced flexibility from conventional plants. It has been shown that the value increases with penetration of RES; however, different systems may require different types of enhanced flexibility features. Moreover, different system scheduling methods, risk attitudes, frequency response requirements and carbon prices could significantly change the value of flexibility.
Strategic distribution network planning with smart grid technologies
Creators: name: Mohtashami, Sara
Publisher: name: Imperial College London
Year: 2014

description: Increased penetration of distributed generations in distribution networks are altering the technical characteristics of the grid, pushing them to operate closer to their limits of safe and reliable operation. New renewable generators connecting to the distribution network will be constrained due to the presence of thermal and voltage constraints during times of low demand and high generation output. The traditional reinforcement planning by means of increasing the capacity of network assets can be very costly and usually ends up in overinvested network with low utilization rates of the assets. In recent years, some smart technologies have been introduced to be used to increase the utilization of network assets and provide the adequate capacity for Distributed Generations (DGs). These smart solutions can help the Distributed Network Operators (DNOs) to provide cheaper and faster network connections for DGs. This thesis presents a multi epoch Optimal Power Flow (OPF) model for capacity and voltage management of a distribution network for integrating new DGs. The model uses the smart solutions including Dynamic Line Rating (DLR), Quad-Booster (QB), Static VAR Compensator (SVC) and Automatic Network Management (ANM) for DGs as well as the traditional reinforcement options. Also the model finds the optimal connection points for new DGs to reduce the cost of network investment and DG curtailment. The multi epoch model is solved with both incremental approach where the investment is carried out incrementally and with integrated approach where the planning is done strategically anticipating the future needs of the network. It compares the application of smart solutions in short and long term planning. The proposed model is applied to a generic UK distribution network and the results are discussed.
Global fits of supersymmetric models after LHC Run 1
Creators: name: De Vries, Kees Jan
Publisher: name: Imperial College London
Year: 2015

description: In this thesis up-to-date global fits are presented of four benchmark models within the R-parity conserving Minimal Supersymmetric extension of the Standard Model (MSSM): the constrained MSSM (CMSSM) and two Non-Universal Higgs Mass (NUHM) models, for which soft supersymmetry-breaking input parameters are defined at the Grand Unified Theory (GUT) scale, as well as a 10-parameter phenomenological MSSM model (pMSSM10) for which the input parameters are defined at the MSUSY scale. These global fits take into account experimental constraints from flavour physics, electroweak precision observables, the anomalous magnetic dipole moment of the muon, cosmological constraints on the dark matter relic density, direct detection experiments for dark matter, properties of the Higgs boson, and searches for supersymmetric particles from Run 1 of the LHC with 20 fb−1 of proton proton collisions at √s = 8 TeV. This thesis contains a careful assessment of the impact of experimental constraints on the parameter spaces of the models. Predictions for physical observables and the corresponding prospects for future runs of the LHC, as well as other experiments, are discussed in detail. Novel features of the global fits of the CMSSM, NUHM1, and NUHM2 presented in this thesis include a comprehensive characterisation of the annihilation processes that bring the dark matter relic density in the cosmologically allowed range. The global fit of the pMSSM10 is the first global fit of a pMSSMn model that fully implements searches for supersymmetric particles from Run 1 of the LHC. The validation of these implementations is discussed in detail.
Particle interactions in high temperature plasmas
Creators: name: Pike, Oliver
Publisher: name: Imperial College London
Year: 2015

description: High temperature plasmas are ubiquitous in high energy astrophysics and are becoming increasingly accessible in the laboratory. This thesis is concerned with two interactions that are important in these systems. The first is the Coulomb interaction, which influences phenomena in systems ranging from controlled fusion experiments to catastrophic astrophysical events. In many of these cases, the motion of the electrons is relativistic. To account for this we extend Spitzer’s famous work on dynamical friction in a plasma to relativistic interactions, deriving the Fokker-Planck coefficients and test particle relaxation rates in the same analytical form as Trubnikov’s classical results. Following this, we present a self-consistent transport theory for a relativistic, magnetised plasma, including simple polynomial fits to the transport coefficients for various values of atomic number. This is the relativistic generalisation of the work of Braginskii and, within the confines of linear transport theory, is valid for all temperatures and field strengths of interest. These results are subsequently verified using Monte Carlo simulations, and the effects of non-Gaussian multiple scattering on transport in a plasma are shown to be small. Beyond relativistic corrections, high temperature plasmas are fundamentally different to their classical counterparts due to the possibility of pair production. One of the primary mechanisms for this and the second interaction we consider is the Breit-Wheeler process: the formation of an electron-positron pair in the collision of two photons. Despite being the simplest way in which light can be converted into matter, this process has never been directly observed in the laboratory. Here, we present a new design of photon-photon collider, in which a laser wakefield-driven gamma-ray beam is fired into the high temperature radiation field of a laser-heated hohlraum. On matching experimental parameters to current facilities, Monte Carlo simulations suggest this is capable of producing over 10^5 Breit-Wheeler pairs per shot.
Additional file 3 of The association between RGS4 and choline in cardiac fibrosis
Creators: name: Guo, Jing
name: Hang, Pengzhou
name: Yu, Jie
name: Li, Wen
name: Zhao, Xiuye
name: Sun, Yue
name: Fan, Ziyi
name: Du, Zhimin
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2. The effect of RGS4 on oxidative stress in MI mice.
The role of transmission networks in the evolution of a low carbon electricity system in the UK
Creators: name: Hughes, Nicholas
Publisher: name: Imperial College London
Year: 2014

description: The UK’s commitments to addressing climate change require a radical restructuring of the electricity sector. This thesis examines what role the electricity transmission networks could play in this transformation. In order to examine the possible role of policy making within a socio-technical system under conditions of long-term uncertainty, a novel scenario method is developed which accounts for political values, actor dynamics and technological networks. The approach is used to examine possible pathways for the electricity transmission network within alternative policy value-sets, which are defined by the level of locational signal provided to generators in respect of their network usage, and the degree of anticipatory or strategic planning involved in network policy. The scenarios emphasise the importance of a locational signal which acts at the operational timescale as well as the investment timescale. They also suggest a role for strategic coordination, particularly to join up planning across onshore, offshore and interconnector regimes. However, due to the range of possible generation and network configurations the scenarios span, they do not support the idea of a central design authority working to a single network blueprint. Specific policy recommendations aim to incorporate these suggestions within the grain of the existing policy trajectory and its prevailing value system. The two principle policy recommendations are therefore, the inclusion of a locational signal within the BSUoS charge in order to better reflect network usage at the operational timescale, and the establishment of an independent body with a remit to identify and contribute needs cases for cross-regime strategic coordination opportunities. The latter recommendation could be achieved with some adaption and clarification of the remit of the ENSG.
Phase correlation-based illumination-insensitive image matching for terrain-related applications
Creators: name: Wan, Xue
Publisher: name: Imperial College London
Year: 2015

description: The Earth surface is monitored by air-borne and space-borne sensors locally, regionally and globally and at short time intervals. The capability of multi-temporal image matching is essential for many terrain-related applications, such as glacier motion monitoring, landslide localisation and earthquake deformation assessment. Robust image matching using time-varying remotely sensed data is, however, not always achievable because images are acquired separately, under different illumination conditions. For remotely sensed images of natural landscapes, such as mountains, deserts and glaciers, the majority of image patterns is produced by topographic features, such as shading and shadows. The appearances of these image patterns can be greatly altered by illumination variation, especially local illumination variation caused by solar position change, and thus parts of the images may lose correspondence for accurate matching. This research provides a thorough mathematical analysis of the impact of local illumination variation via Phase Correlation (PC) cross power spectrum in the Fourier frequency domain and thus proves the illumination-insensitive property of PC-based image matching algorithms. Specifically, the relationship between PC fringe appearance and sun angle variation is investigated. Two improved PC based approaches, ADCF-PC (Absolute Dirichlet Curve Fitting based Phase Correlation) and PLSF-PC (Piecewise Least Square Fitting based Phase Correlation), are presented and compared for illumination-insensitive image matching. Finally, three original approaches to explore terrain related applications have been developed including: vision-based UAV navigation, illumination-insensitive change detection and DEM generation from multi-temporal remotely sensed images.
Berchemia lineata
Creators: name: Jarvis, Charlie
Publisher: name: Linnaean Society of London in association with the Natural History Museum
Year: 2007
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Rosales
Rhamnaceae
Berchemia
Berchemia lineata

description: Rhamnus lineata Linnaeus, Centuria II Plantarum: 11. 1756.
"Habitat in Zeylona, China. Osbeck." RCN: 1564.
Type not designated.
Original material: Herb. Linn. No. 262.23? (LINN).
Current name: Berchemia lineata (L.) DC. (Rhamnaceae).
description: Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part R), pp. 785-805 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 791, DOI: 10.5281/zenodo.291971
A Deep Multicolor Survey. IV. The Electronic Stellar Catalog
Creators: name: Osmer, Patrick S.
name: Kennefick, Julia D.
name: Hall, Patrick B.
name: Green, Richard F.
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We make available in electronic form the stellar catalog of 19,494 objects from the Deep Multicolor Survey (DMS). The DMS is based on CCD imaging with the Mayall 4-m telescope in U,B,V,R',I75,I86 and covers 0.83 sq. deg. in six fields at high galactic latitude. The survey reached 5 sigma limiting magnitudes of 22.1 in I86 to 23.8 in B. The catalog gives positions, magnitudes and error estimates, and classification codes in the six filter bands for all the objects. We present tables that summarize the spectroscopic results for the 55 quasars, 44 compact narrow emission-line galaxies, and 135 stars in the DMS that we have confirmed to date. We also make available illustrations of all the spectra. The catalog and spectra can be obtained from the World Wide Web at http://www.astronomy.ohio-state.edu/~posmer/DMS/.
description: 10 pages, 3 figures, 3 tables, accepted for publication in ApJ Supplement
title: ADCO, Grènetier de Cîteaux : comptes (1497-1504) (11 H 1172), f. 00111
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes

description: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1497-1504), Archives départementales de la Côte-d'Or, (11 H 1172), f. 00111, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Clinical evaluation of a novel close-loop insulin delivery system in type 1 diabetes
Creators: name: Reddy, Monika
Publisher: name: Imperial College London
Year: 2015

description: Type 1 diabetes (T1DM) is managed by exogenous insulin administration, either by multiple daily injections (MDI) of insulin or via continuous subcutaneous insulin infusion (CSII). Despite intensive insulin therapy and structured education a significant proportion of people with T1DM are unable to achieve optimal glucose control without the risking recurrent hypoglycaemia. Longstanding hyperglycaemia can lead to microvascular and macrovascular complications, whereas hypoglycaemia can lead to seizures, arrhythmias and ‘dead in bed’ syndrome. A closed-loop insulin delivery system, consisting of a glucose sensor measuring interstitial glucose, a control algorithm and an insulin pump for subcutaneous insulin delivery, has the potential to improve glucose control, reduce hypoglycaemia, reduce long-term diabetes associated complications and improve overall quality of life. A novel closed-loop system has been developed by the Imperial College Diabetes Technology Team. The Bio-inspired Artificial Pancreas (BiAP), uses a control algorithm based on mathematical model of pancreatic beta-cell physiology implemented in a microchip integrated in small low-powered handheld device. This thesis outlines the ‘first in human’ clinical evaluation of the Bio-inspired Artificial Pancreas in adults with T1DM. The safety and efficacy of the system has been evaluated incrementally, initially fasting over 6 hours, followed by 13-hour overnight and post-meal study and finally in a 24-hour randomised controlled trial which included assessment of the algorithm without meal announcement. The feasibility of the BiAP system with glucagon was evaluated in a 6-hour fasting study. A separate sub-study evaluating whether glycaemic variability impacts quality of life in adults with type 1 diabetes on either MDI or CSII was also conducted. The results of the studies demonstrated that the Imperial College closed-loop insulin delivery system is safe and achieved a significant reduction in hypoglycaemia when compared to standard therapy (insulin pump), particularly overnight. Glycaemic variability was shown to have no significant impact on overall or subscale quality of life in adults with type 1 diabetes, irrespective of whether they are on MDI or CSII.
Correlated electronic–nuclear dynamics in strong laser fields
Creators: name: Medisauskas, Lukas
Publisher: name: Imperial College London
Year: 2015

description: This thesis investigates how atoms and molecules behave once a coherent electronic dynamics is excited by a high frequency attosecond pulse, via single photon ionization, low frequency IR pulse, via multiphoton ionization, or a combination of both. In particular, the focus is made on the role of vibrational dynamics and how the correlation between the vibrational and electronic dynamics influences the outcomes of induced processes. First, the role of electronic coherence in modifying the optical properties of atoms is investigated in the context of circularly polarized harmonic generation. Next, we move to simple molecular systems and study the coupling between such electronic coherence and vibrational dynamics after photoionization of H2 molecules where we focus on the formation of photoionization lineshapes. It is further shown how the initial electronic coherence can modify long-term vibrational dynamics of a molecule by studying dissociative ionization of N2 molecule in an attosecond-XUV+IR pump--probe experiment. Both numerical and analytical approaches are used in this thesis. The numerical approaches involve solving the time-dependent Schrödinger equation for the electron wavepacket in atomic potential or the vibrational wavepacket on molecular potential energy curves. The numerical calculations are aided by analytical analysis based on strong field approximation and semiclassical methods. The phase-lock between excited electronic wavepackets and the time synchronization between the electronic and vibrational dynamics is established as the central object of molecular attosecond science, which allows one to achieve attosecond precision in measurements and coherent control.
Additional file 7: of Comparative transcriptome analysis of Eimeria maxima (Apicomplexa: Eimeriidae) suggests DNA replication activities correlating with its fecundity
Creators: name: Dandan Hu
name: Chaoyue Wang
name: Wang, Si
name: Xinming Tang
name: Chunhui Duan
name: Sixin Zhang
name: Jinxia Suo
name: Miner Deng
name: Yanli Lv
name: Suo, Xun
name: Xianyong Liu
Publisher: name: figshare
Year: 2018
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology

description: Mean-abundance (MA) plots and Volcano plots comparisons of DEGs between BJ-WT-130 and BJ-PL-98 in three different development stages. (PDF 1425 kb)
Failure of Perturbation Theory Near Horizons: the Rindler Example
Creators: name: Burgess, C. P.
name: Hainge, Joshua
name: Kaplanek, Greg
name: Rummel, Markus
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Persistent puzzles to do with information loss for black holes have stimulated critical reassessment of the domain of validity of semiclassical EFT reasoning in curved spacetimes, particularly in the presence of horizons. We argue here that perturbative predictions about evolution for very long times near a horizon are subject to problems of secular growth - i.e. powers of small couplings come systematically together with growing functions of time. Such growth signals a breakdown of naive perturbative calculations of late-time behaviour, regardless of how small ambient curvatures might be. Similar issues of secular growth also arise in cosmology, and we build evidence for the case that such effects should be generic for gravitational fields. In particular, inferences using free fields coupled only to background metrics can be misleading at very late times due to the implicit assumption they make of perturbation theory when neglecting other interactions. Using the Rindler horizon as an example we show how this secular growth parallels similar phenomena for thermal systems, and how it can be resummed to allow late-time inferences to be drawn more robustly. Some comments are made about the appearance of an IR/UV interplay in this calculation, as well as on the possible relevance of our calculations to predictions near black-hole horizons.
description: LaTeX, 17 pages plus appendix; added references and subsection on back-reaction
Reminiscences of Marquis W. Childs, 1958
Publisher: name: Columbia University
Year: 2021
Subjects: Journalists
Journalism
Presidents--Election--1936

description: Education and early work on the St. Louis POST-DISPATCH; impressions of Chicago and St. Louis journalists; coverage of the 1936 presidential campaign; impressions of members of the Supreme Court; Robert H. Jackson, Harlan Stone, and Felix Frankfurter
Dynamically integrated transport approach for heavy-ion collisions at high baryon density
Creators: name: Akamatsu, Yukinao
name: Asakawa, Masayuki
name: Hirano, Tetsufumi
name: Kitazawa, Masakiyo
name: Morita, Kenji
name: Murase, Koichi
name: Nara, Yasushi
name: Nonaka, Chiho
name: Ohnishi, Akira
Publisher: name: arXiv
Year: 2018
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We develop a new dynamical model for high energy heavy-ion collisions in the beam energy region of the highest net-baryon densities on the basis of non-equilibrium microscopic transport model JAM and macroscopic 3+1D hydrodynamics by utilizing a dynamical initialization method. In this model,dynamical fluidization of a system is controlled by the source terms of the hydrodynamic fields. In addition, time dependent core-corona separation of hot regions is implemented. We show that our new model describes multiplicities and mean transverse mass in heavy-ion collisions within a beam energy region of $3
description: 8 pages, 8 figures, new figures added; published in Physical Review C
Systemic Ropivacaine Concentrations Following Local Infiltration Analgesia and Femoral Nerve Block in Older Patients Undergoing Total Knee Arthroplasty
Creators: name: Sigita Kazune
name: Inga Nurka
name: Matiss Zolmanis
name: Arturs Paulausks
name: Dace Bandere
Publisher: name: Zenodo
Year: 2023
Subjects: arthroplasty, anesthetic techniques, regional, anesthetics local, ropivacaine, toxicity, local anesthetics

description: Purpose: The study examined the pharmacokinetic profile of fixed formulation mixtures comprising 225 mg of ropivacaine for localinfiltration analgesia with or without epinephrine, and femoral nerve block in older patients presenting for orthopedic surgery andexplored potential influences of block type, age, and body weight on this profile.Patients and Methods: Twenty four patients scheduled for total knee arthroplasty were randomly assigned to three groups: femoralnerve block, local infiltration analgesia with epinephrine and local infiltration analgesia without epinephrine. Blood samples werecollected at 10, 30, 60, and 120 min following the block and total plasma concentrations of ropivacaine were quantified by highperformance liquid chromatography.Results: The mean individual peak total plasma concentrations of ropivacaine in local infiltration analgesia with and withoutepinephrine, and femoral nerve block group were 0.334, 0.490 and 0.545 μg mL −1 (p = 0.16). Local infiltration with epinephrinegroup had significantly lower plasma ropivacaine concentrations at 30, 60 and 120 minutes. The plasma ropivacaine concentrationsexceeded 2.2 μg mL−1 in one patient. Age, but not body weight, had a moderate correlation with peak plasma ropivacaineconcentration (r = 0.37, p = 0.08).Conclusion: Administration of a fixed 225 mg dose of ropivacaine for local infiltration analgesia with epinephrine and femoral nerveblock results in plasma ropivacaine concentrations below the toxicity threshold, indicating their safety. The use of local infiltrationanalgesia with epinephrine provides a greater safety margin, as local infiltration analgesia without epinephrine may lead to ropivacaineconcentrations associated with symptoms of local anesthetic toxicity.
Extracting bias using the cross-bispectrum: An EoR and 21 cm-[CII]-[CII] case study
Creators: name: Beane, Angus
name: Lidz, Adam
Publisher: name: arXiv
Year: 2018
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The amplitude of redshifted 21 cm fluctuations during the Epoch of Reionization (EoR) is expected to show a distinctive "rise and fall" behavior with decreasing redshift as reionization proceeds. On large scales (k b_21(z) using a combination of future redshifted 21 cm and [CII] line-intensity mapping data sets. Our method exploits the dependence of the 21 cm-[CII]-[CII] cross-bispectrum on the shape of triangle configurations in Fourier space. This allows one to determine b_21(z) yet, importantly, is less sensitive to foreground contamination than the 21 cm auto-spectrum, and so can provide a valuable cross-check. We compare the results of simulated bispectra with second-order perturbation theory: on large scales the perturbative estimate of b_21(z) matches the true value to within 10% for
description: 14 pages, 10 figures, ApJ accepted; comments welcome; updated to match accepted version
Surface analysis of simulant UK high level waste glass
Creators: name: Ahmad, Nor Ezzaty
Publisher: name: Imperial College London
Year: 2015

description: Simulated waste glasses which were 25 wt% Magnox glass, 36 wt% Magnox glass and International Simple Glass (ISG) were subjected to aqueous corrosion in static mode with deionised water at 90 °C for 7 to 28 days. Magnox glass is Mg- and Al- rich while ISG has only 6 components but no Mg in the composition. These glasses were assessed before and after corrosion using X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM) with Energy X-Ray Dispersive Spectrocopy (EDX), Transmission Electron Microscopy (TEM), Ion-ToF Secondary Ion Mass Spectrometry (ToF-SIMS) and Inductively Coupled Plasma – Optical Electron Spectroscopy (ICP-OES) in particular a novel wedge technique was developed for ToF-SIMS enabling accurate assessment of corrosion. Characterisation reveals changes in the morphology and elemental distributions from the surface to the bulk. Depletion of alkali ions i.e Na and Li was observed indicating the interdiffusion (ion exchange) process occurs after leaching. Formation of a gel layer which was Si-rich was also observed which forms due to the hydrolysis process. Formation of alteration layers were also observed on the glass due to leachates saturation which enables released ions to be sorbed and precipitate on the glass surface. It is found that high waste loading glass (36 wt% Magnox) has higher durability compared to the other glasses as it has a lower leaching rate that is 0.7 gm-2d-1 compared to 2.1 gm-2d-1 and 22 gm-2d-1 for 25 wt% Magnox glass and ISG glass respectively. The level of each element was determined and its role in the glass structure, either acting as modifier or intermediate, was identified.
Skewness of Cosmic Microwave Background Temperature Fluctuations Due to Non-linear Gravitational Instability
Creators: name: Munshi, Dipak
name: Souradeep, Tarun
name: Starobinsky, Alexei A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Skewness of temperature fluctuations of the cosmic microwave background (CMB) produced by initially Gaussian adiabatic perturbations with the flat (Harrison-Zeldovich) spectrum, which arises due to non-linear corrections to a gravitational potential at the matter-dominated stage, is calculated quantitatively. For the standard CDM model, the effect appears to be smaller than expected previously and lies below the cosmic variance limit even for small angles. The sign of the skewness is opposite to that of the skewness of density perturbations.
description: The final version to appear in ApJ, minor changes are made and 3 references are added
Effect of reinforcement spacers on concrete microstructure and durability
Creators: name: Alzyoud, Sukina
Publisher: name: Imperial College London
Year: 2015

description: Reinforcement spacers (i.e. bar supports, chairs) are crucial elements of reinforced concrete, but their influence on the microstructure and long-term durability is not clear. This study investigates the effect caused by plastic and cementitious spacers, and steel wire chairs combined with different aggregate sizes, curing and conditioning regimes on the transport properties, microstructure and chloride-induced corrosion of concrete structures. Concrete cylindrical samples were prepared with 25 and 50 mm high plastic, steel and cementitious spacers. Samples were then cured, conditioned and tested for oxygen diffusivity, oxygen permeability, water sorptivity and chloride diffusivity. Selected samples were pressure impregnated with fluorescent epoxy to study the extent and spatial distribution of epoxy intrusion. The interfacial zone between the spacer and concrete was examined using field-emission scanning electron microscope in the backscattered electron (BSE) mode. The ingress of chloride, particularly near the interface between spacers and concrete matrix was studied using micro X-ray fluorescence (μXRF). The effect of plastic and cementitious spacers on chloride- induced corrosion via capillary rise and cyclic wetting/drying was investigated using small reinforced concrete beams. The feasibility of improving the bond between spacer and concrete by increasing surface roughness of plastic spacers was also investigated. Results show that concrete samples containing plastic spacers consistently gave the least resistance to transport and the highest epoxy penetration followed by samples with cementitious spacers, and then steel spacers. The control samples (samples without spacers) had the highest resistance to transport in all cases. The epoxy penetration occurred mainly through the spacer-concrete interface. The microstructure of the spacer-concrete interface showed significantly lower cement content and higher porosity compared to 'bulk paste' farther away form the interface. Higher penetration of chloride ions was detected along spacer-concrete interface compared to the control sample or the bulk paste farther away. It is evident that spacers initiate early corrosion and this may reduce the service-life of reinforced concrete structures. The implications of these findings on durability of concrete structures are discussed. Several recommendations to improve the bond at the interface between spacer and concrete are presented.
Reminiscences of Martha Hill 1979
Publisher: name: Columbia University
Year: 2019
Subjects: Dance teachers
Dancers
Modern dance
Dance--Production and direction

description: Early dance training; experiences studying and performing with Martha Graham; teaching posts: Lincoln School, New York University, Bennington College; genesis of summer school idea; curriculum for summers; financial arrangements; impressions of Robert D. Leigh and Mrs. Leigh, Louis Horst, John Martin; working with Doris Humphrey, Charles Weidman, Hanya Holm, Martha Graham, Arch Lauterer, Norman Lloyd, Mary Jo Shelly in summer school and productions.
Additional file 5 of Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis
Creators: name: Lee, Ji-Hyun
name: Jung, Jae Hun
name: Kim, Jeesoo
name: Baek, Won-Ki
name: Rhee, Jinseol
name: Kim, Tae-Hwan
name: Kim, Sang-Hyon
name: Kim, Kwang Pyo
name: Son, Chang-Nam
name: Kim, Jong-Seo
Publisher: name: figshare
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 5: Figure S1. Verification of C4A, MBL2, and APCS in synovial fluid by western blot. (a) Western blot analysis in the original synovial fluid sample set: A; AS (n = 10), R; RA (n = 10), G; gout (n = 10), and O; OA (n = 10). (b) Western blot analysis in the Independent sample set: AS (n = 5), RA (n = 5), gout (n = 5), OA(n = 5). Transferrin was used as an input amount control.