cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
water-13-02340-v2.pdf
Creators: name: Yee, Brandon Lee
name: Hu, Jiangyong
name: yee, lim fang
name: hao, loh wei
Publisher: name: figshare
Year: 2021
Subjects: subject: Environmental Science
subject: 90402 Catalytic Process Engineering
subject: FOS: Chemical engineering
subject: 90499 Chemical Engineering not elsewhere classified
subject: 90703 Environmental Technologies
subject: FOS: Environmental engineering
subject: 90799 Environmental Engineering not elsewhere classified
subject: 90605 Photodetectors, Optical Sensors and Solar Cells
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: 90409 Wastewater Treatment Processes
subject: 90410 Water Treatment Processes
subject: 90509 Water Resources Engineering
subject: FOS: Civil engineering
subject: 90508 Water Quality Engineering

description: This review discusses novel and new treatment of emerging contaminants using light-based technoplogy. The management of contaminants of emerging concern (CECs) in water bodies is particularly challenging due to the difficulty in detection and their recalcitrant degradation by conventional means. In this review, CECs are characterized to give insights into the potential degradation performance of similar compounds. A two-pronged approach was then proposed for the overall management of CECs. Light-driven oxidation processes, namely photo/Fenton, photocatalysis, photolysis, UV/Ozone were discussed. Advances to overcome current limitations in these light-driven processes were proposed, focusing on recent trends and innovations. Light-based detection methodology was also discussed for the management of CECs. Lastly, a cost–benefit analysis on various light-based processes was conducted to access the suitability for CECs degradation. It was found that the UV/Ozone process might not be suitable due to the complication with pH adjustments and limited light wavelength. It was found that EEO values were in this sequence: UV only > UV/combination > photocatalyst > UV/O3 > UV/Fenton > solar/Fenton. The solar/Fenton process has the least computed EEO < 5 kWh m−3 and great potential for further development. Newer innovations such as solar/catalyst can also be explored with potentially lower EEO values.
Syringaresinol as a novel androgen receptor antagonist against wild and mutant androgen receptors for the treatment of castration resistant prostate cancer: Molecular docking, in-vitro and molecular dynamics study
Creators: name: Divakar Selvaraj
name: Santhoshkumar Muthu
name: Satvik Kotha
name: Ramachandra Setty Siddamsetty
name: Andavar, Sasikumar
name: Saravanan Jayaraman
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Computational Biology

description: Phytoestrogens are dietary estrogens having similar structure as of estrogen. Some of these phytoestrogens are androgen receptor (AR) antagonist and exhibit preventive role in the prostate cancer. However, in androgen independent prostate cancer (AIPC) the ARs were mutated (T877A, W741L, F876L etc) and these mutant ARs convert the antagonist to agonist. Our aim in this study is to find phytoestrogens that could function as an antagonist with wild and mutant ARs. The phytoestrogens were analyzed for binding affinity with wild and mutant ARs in agonist and antagonist conformations. The point mutations were carried out using Chimera. The antagonist AR conformation was modelled using Modeller. We hypothesize that the compounds having binding affinity with agonist AR conformation could not function as a full or pure antagonist. Most of the phytoestrogens have binding affinity with agonist AR conformation contradicting previous results. For example, genistein which is a widely studied isoflavone has known AR antagonist property. However, in our study it had good binding affinity with agonist AR conformation. Hence, to confirm our hypothesis, we tested genistein in LNCaP (T877A mutant AR) cells by qPCR studies. The genistein functioned as an antagonist only in the presence of an androgen indicting a partial agonist type of activity. The in-vitro results supported our docking hypothesis. We applied this principle and found syringaresinol could function as an antagonist with wild and mutated ARs. Further, we carried out molecular dynamics for the hit molecule to confirm its antagonist binding mode with mutant AR.
Constraints on primordial density perturbations from induced gravitational waves
Creators: name: Assadullahi, Hooshyar
name: Wands, David
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We consider the stochastic background of gravitational waves produced during the radiation-dominated hot big bang as a constraint on the primordial density perturbation on comoving length scales much smaller than those directly probed by the cosmic microwave background or large-scale structure. We place weak upper bounds on the primordial density perturbation from current data. Future detectors such as BBO and DECIGO will place much stronger constraints on the primordial density perturbation on small scales.
description: Version to appear in Phys Rev D
Additional file 1 of Cardiometabolic outcomes among schizophrenia patients using antipsychotics: the impact of high weight gain risk vs low weight gain risk treatment
Creators: name: Khandker, Rezaul
name: Chekani, Farid
name: Limone, Brendan
name: Thiel, Ellen
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Figure S1 Commercial and Medicaid Sample Selection.
title: Manifestaciones radiológicas de la Tuberculosis Pulmonar
Creators: name: Salazar Gomez, Angela Patricia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Infection
subject: Cavitation
subject: Atelectasis
subject: CT-High Resolution
subject: Digital radiography
subject: PET-CT
subject: Thorax

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
1.
Revisar los hallazgos radiológicos en placa de tórax y en TC de la Tuberculosis pulmonar en pacientes inmunocompetentes e inmunocomprometidos. 2.
Evaluar el papel de la radiografía de tórax,
el TC y el PET / TC para el diagnóstico de la...
Structure-based virtual screening, free energy of binding and molecular dynamics simulations to propose novel inhibitors of Mtb-MurB oxidoreductase enzyme
Creators: name: Sonam
name: Varun Chahal
name: Kakkar, Rita
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Currently, the growing incidence of drug resistance toward tuberculosis intensified the need for discovery of novel targets and their inhibitors. The enzyme MurB which is involved in one of the steps for peptidoglycan biosynthesis is an effective target that can produce drugs having lesser side effects. Recently the only crystal structure of Mycobacterium Tuberculosis MurB has been deposited and, therefore, in the present study, we have used this as a target for virtual screening of drug-like molecules from the ZINC Database. We have also designed a complete workflow for the process which resulted in 12 hit compounds that have good docking scores, ΔGbind, and Glide energy. The hits obtained have also been found to share structural features with some known antibiotics such as Amoxicillin. Furthermore, MD simulations on the top most hit L1 displayed its stable binding with the enzyme. Thus, this study has proved helpful in proposing novel inhibitors for MurB enzyme that can be tested against various TB strains.
title: Una urgencia infrecuente: Hematomas epidurales y subdurales espinales espontáneos.
Creators: name: Borja Consigliere, Augustin
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: CT
subject: MR
subject: Neuroradiology spine
subject: Emergency
subject: Musculoskeletal spine

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Los hematomas espinales epidurales y subdurales espontáneos son patologías infrecuentes que se presentan como síndromes de compresión medular,
generalmente con un inicio agudo asociado a cervicalgia,
dorsalgia o dolor radicular. Describimos los...
title: Constructing Obstacles: Welchen Einfluss haben Verkehrsabsicherungen an Arbeitsstellen auf die (wahrgenommene) Sicherheit von Radfahrenden?
Creators: name: Klosterkamp, Marie
Publisher: name: Universität Kassel
Year: 2023
Subjects: subject: bike
subject: pedestrian
subject: construction site
subject: infrastructure
subject: safety
subject: interaction
subject: 150
subject: 380
subject: Radfahren
subject: Fußgänger
subject: Baustelle
subject: Verkehrssicherheit

description: Posterbeitrag / Konferenz: Vierter Kongress der Fachgruppe Verkehrspsychologie, 2023
title: Ecografía con contraste (CEUS) en el ámbito de urgencias: indicaciones, hallazgos y nuevas aplicaciones.
Creators: name: Alfageme Zubillaga, Marta
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Trauma
subject: Acute
subject: Diagnostic procedure
subject: Contrast agent-intravenous
subject: Ultrasound-Power Doppler
subject: Ultrasound-Colour Doppler
subject: Ultrasound
subject: Trauma
subject: Abdomen

description: Objetivo docente
Revisión del tema
Conclusiones
Bibliografía
description: Objetivo docente:
Describir la técnica de realización de ecografía con contraste (CEUS) y establecer sus indicaciones y nuevas aplicacionesen el ámbito de urgencias. Describir los hallazgos radiológicos en las patologías urgentes más frecuentes en nuestro...
Non-enzymatic glycation of human serum albumin modulates its binding efficacy towards bioactive flavonoid chrysin: A detailed study using multi-spectroscopic and computational methods
Creators: name: Sharat Sarmah
name: Somdev Pahari
name: Sourav Das
name: Belwal, Vinay Kumar
name: Madhurima Jana
name: Atanu Singha Roy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The non-enzymatic glycation of plasma proteins by reducing sugars have important consequences on the conformational and functional properties of protein. The formation of advanced glycation end products (AGEs) is responsible for cell death and other pathological conditions. We have synthesized the glycated human serum albumin (gHSA) and characterized the same by using differential spectroscopic measurements. The aim of the present study is to determine the effect of glycation on the binding of human serum albumin (HSA) with bioactive flavonoid chrysin, which possesses anti-cancer, anti-inflammatory and anti-oxidant activities. The interaction of chrysin with HSA and gHSA was studied using multi-spectroscopic, molecular docking and molecular dynamics (MD) simulation techniques. Chrysin quenched the intrinsic fluorescence of both HSA and gHSA by static quenching mechanism. The value of the binding constant (Kb) for the interaction of HSA-chrysin complex (4.779 ± 0.623 × 105 M−1 at 300 K) was found to be higher than that of gHSA-chrysin complex (2.206 ± 0.234 × 105 M−1 at 300 K). Hence, non-enzymatic glycation of HSA significantly reduced its binding affinity towards chrysin. The % α-helicity of HSA was found to get enhanced upon binding with chrysin, and minimal changes were observed for the gHSA-chrysin complex. Site marker probe studies indicated that chrysin binds to subdomain IIA and IIIA of both HSA and gHSA. The results from molecular docking and MD simulation studies correlated well with the experimental findings. Electrostatic interactions followed by hydrogen bonding and hydrophobic interactions played major roles in the binding process. These observations may have some useful insights into the field of pharmaceutics.
title: Extraction of proteins from soybean residue (okara) and investigation of their physicochemical properties and their application as emulsifiers
Creators: name: Eze, Ogemdi Florence
Publisher: name: University of Reading
Year: 2019

description: Soybean products and in particular soymilk have received significant attention by the public in recent years. Their increasing popularity is primarily due to their nutritional composition and potential health benefits as well as the fact that they are lactose-free and cholesterol-free which makes them ideal alternatives to cow milk especially by lactose intolerant people as well as people suffering from hypercholesterolemia. Okara is a protein-rich residue produced at significant amounts during soy milk production and thus constitutes an abundant and cheap raw material that can be used for the extraction of proteins with potential applications in the food industry as functional food ingredients. The aim of this research was to evaluate alkaline extraction and ultrasonication for the extraction of okara proteins, build our knowledge on the relationship between the extraction method, the protein structure and its functions, as well as investigate the application of the extracted proteins in a mayonnaise-like emulsion system. The results demonstrated that alkaline extraction in 0.1 M phosphate buffer at pH 12 and at 60 oC for 60 mins resulted in significantly higher protein extraction from okara (~ 36 % w/w) compared to pH 9,10 and 11 ranging from 4 – 14 % in these cases. The main protein components in the extracts were 11 S (glycinin) and 7 S (β-conglycinin) as observed with SDS-PAGE analysis; further separation and purification resulted in the protein content of 83-86 % protein compared to the starting okara material. The pH of the extraction had a considerable effect on the structure of the protein as demonstrated by the Fourier transform infrared spectroscopy. It also improved the physicochemical properties of the okara protein isolate (OPI) such as its protein solubility, zeta potential, size distribution and emulsion properties. An ultrasonication method further improved the extraction yield to higher than 100% (compared to the standard solvent method). Ultrasonication also improved the physicochemical properties without affecting the purity of the protein. The rheological data revealed that ultrasonication derived OPI had the best rheological properties compared to the conventional derived OPI and commercial protein isolate.
title: Calidad de imagen en TC de columna instrumentada: comparación en reconstrucción monoenergética vs 140Kv.
Creators: name: Silva Priegue, Noelia
Publisher: name: Sociedad Española de Radiología Médica
Year: 2014
Subjects: subject: Prostheses
subject: Artifacts
subject: Computer Applications-Detection, diagnosis
subject: CT
subject: Neuroradiology spine

description: Objetivos
Material y método
Resultados
Conclusiones
Bibliografía
description: Objetivos:
Comparar la calidad del hueso,
la visualización del material de osteosíntesis y del hueso adyacente al material de osteosíntesis y valorar el artefacto de la TC de columna lumbar instrumentada con energía dual: imagen monoenergética frente a la...
Deepest limits on scattered light emission from the Epsilon Eridani inner debris disk with HST/STIS
Creators: name: M., Sai Krishanth P.
name: Douglas, Ewan S.
name: Anche, Ramya M.
name: Hom, Justin
name: Cahoy, Kerri L.
name: Debes, John H.
name: Jang-Condell, Hannah
name: Rebollido, Isabel
name: Ren, Bin B.
name: Stark, Christopher C.
name: Thompson, Robert
name: Xin, Yinzi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: Epsilon Eridani ($ε$ Eri) is one of the first debris disk systems detected by the Infrared Astronomical Satellite (IRAS). However, the system has thus far eluded detection in scattered light with no components having been directly imaged. Its similarity to a relatively young Solar System combined with its proximity makes it an excellent candidate to further our understanding of planetary system evolution. We present a set of coronagraphic images taken using the Space Telescope Imaging Spectrograph (STIS) coronagraph on the Hubble space telescope at a small inner working angle to detect a predicted warm inner debris disk inside 1". We used three different post-processing approaches; Non-negative Matrix Factorization (NMF), Karhunen-Lo`eve Image Processing (KLIP), and Classical reference differential imaging (RDI), to best optimize reference star subtraction, and find that NMF performed the best overall while KLIP produced the absolute best contrast inside 1". We present limits on scattered light from warm dust, with constraints on surface brightness at 6 mJy/as$^2$ at our inner working angle of 0.6". We also place a constraint of 0.5 mJy/as$^2$ outside 1", which gives us an upper limit on the brightness for outer disks and substellar companions. Finally, we calculated an upper limit on the dust albedo at $ω<$ 0.487.
description: 13+2 pages, 7+2 figures; Accepted for publication in the Astronomical Journal
A quantum logical and geometrical approach to the study of improper mixtures
Creators: name: Domenech, Graciela
name: Holik, Federico
name: Massri, Cesar
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study improper mixtures from a quantum logical and geometrical point of view. Taking into account the fact that improper mixtures do not admit an ignorance interpretation and must be considered as states in their own right, we do not follow the standard approach which considers improper mixtures as measures over the algebra of projections. Instead of it, we use the convex set of states in order to construct a new lattice whose atoms are all physical states: pure states and improper mixtures. This is done in order to overcome one of the problems which appear in the standard quantum logical formalism, namely, that for a subsystem of a larger system in an entangled state, the conjunction of all actual properties of the subsystem does not yield its actual state. In fact, its state is an improper mixture and cannot be represented in the von Neumann lattice as a minimal property which determines all other properties as is the case for pure states or classical systems. The new lattice also contains all propositions of the von Neumann lattice. We argue that this extension expresses in an algebraic form the fact that -alike the classical case- quantum interactions produce non trivial correlations between the systems. Finally, we study the maps which can be defined between the extended lattice of a compound system and the lattices of its subsystems.
description: submitted to the Journal of Mathematical Physics
Screening of inhibitors as potential remedial against Ebolavirus infection: pharmacophore-based approach
Creators: name: Muthumanickam Sankar
name: Langeswaran K
name: Sangavi Jeyachandran
name: Boomi Pandi
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Ebola virus disease (EVD) has been recognized as a major threat for humans and primates. Till now, therapeutic solution is a challenging for the treatment of Ebola virus disease. Therefore, new, novel with suitable effective antiviral drug against EVD is essential. In the present study pharmacophore modeling, 3DQSAR, molecular docking, DFT and molecular dynamic simulations were used to identify the new, novel with suitable effective potential inhibitors against Ebola virus through the computational methods. From the pharmacophore PHASE modeling, the best five hypothesis pharmacophore features such as three hydrogen bond acceptor, one positive ion and one aromatic ring are taken to study the 3D-QSAR structural model. The designed with correlation co-efficient is found to be R2 = 0.92 and the excellent predictive power with correlation co- efficient is found to be Q2 = 0.82. The 3D-QSAR model is used to study the virtual screening against the chemical libraries compounds (NCI, ZINC, Asinex, LifeChemical, ChemBridge, MayBridge, Enamine and specs) to identify the novel scaffolds. The best binding free energy (39.368769 kcal/mol) and the best docking score (12.419 kcal/mol) for NCI database are obtained from molecular docking and MM-GBSA respectively. The good electronic features of ligands are observed from DFT analysis. Finally, molecular dynamics simulations revealed the stability of ligand protein complexes ranging from 1 nm to 1.5 nm. We anticipated that, this ligand protein complex could be supportive to improve the potent inhibitor against the Ebola viral treatment. Communicated by Ramaswamy H. Sarma.
Nonlinear resonant photoionization in molecular iodine
Creators: name: Sil, Georgena Sarah Petty
Publisher: name: University of British Columbia
Year: 2010

description: Strong photoionization spectra have been observed in molecular Iodine following laser excitation in the near ultraviolet. The dependence upon laser power, and the structure of the spectra are consistent with three-photon ionization with resonance in an intermediate state excited by two photons. Vibrational analysis indicates an electronic energy T[sub e] of 53,562.75 ± 1 cm⁻¹, a harmonic vibrational constant we of 241.4 ± 0.4 cm⁻¹, and an anharmonic vibrational constant toexe of 0.58 ± 0.06 cm⁻¹. Rotational analysis done by the Franck-Condon method, whereby the relative experimental band intensities are compared with theoretical values, indicates that the internuclear separation r[sub e] in the resonant electronic state is 2.567 ± 0.002A, corresponding to a rotational constant B of 0.04029 ± 0.00007 cm⁻¹. The new electronic state has, with high probability, the designation 1[sub g] . Several im purity lines were observed at exciting energies 26,297.14 ± 1 cm⁻¹ (half width 8.09 cm⁻¹), at 26,915.22 ± 1 cm⁻¹, and at 27,343.96 ± 1 cm⁻¹. The impurity signal varies as I[sub o][sup 2.02]. The features likely arise from complex molecular species formed in reactions at high temperature with l₂, and have not been identified. The photoionization efficiency of in nonlinear absorption exhibits an apparent resonance in the vicinity of 80,000 cm⁻¹ in terms of total molecular energy.
Social housing: interventions of densification in urban regeneration (1995-2010). 
Critical analysis of strategies adopted in Milan, London, São Paulo
Social housing: interventi di densificazione per la rigenerazione urbana (1995-2010).
Analisi critica delle strategie adottate a Milano, Londra, San Paolo
Creators: name: Boito, Andrea <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2013
Subjects: ICAR/14 Composizione architettonica e urbana

description: The prospect of the continuous multiplication of life styles, the obsolescence of the traditional typological diagrams, the usability of spaces on different territorial scales, imposes on contemporary architecture the search for new models of living. Limited densities in urban development have produced the erosion of territory, the increase of the harmful emissions and energy consumption. High density housing cannot refuse the social emergency to ensure high quality and low cost dwellings, to a new people target: students, temporary workers, key workers, foreign, young couples without children, large families and, in general, people who carry out public services. Social housing strategies have become particularly relevant in regenerating high density urban outskirts. The choice of this research topic derives from the desire to deal with the recent accommodation emergency, according to different perspectives, with a view to give a contribution to the current literature, by proposing some tools for a correct design of the social housing, by ensuring good quality, cost-effective, and eco-sustainable solutions, from the concept phase, through management and maintenance, until the end of the building life cycle. The purpose of the thesis is defining a framework of guidelines that become effective instruments to be used in designing the social housing. They should also integrate the existing regulations and are mainly thought for those who work in this sector. They would aim at supporting students who have to cope with this particular residential theme, and also the users themselves. The scientific evidence of either the recent specialized literature or the solutions adopted in some case studies within the selected metropolitan areas of Milan, London and São Paulo, it is possible to identify the principles of this new design approach, in which the connection between typology, morphology and technology pursues the goal of a high living standard.
Skyrme-Hartree-Fock-BCS approach to $^{229m}$Th and neighboring nuclei
Creators: name: Minkov, Nikolay
name: Pálffy, Adriana
name: Quentin, Philippe
name: Bonneau, Ludovic
Publisher: name: arXiv
Year: 2024
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The microscopic origin of the $^{229m}$Th isomer and its possible manifestation also in neighboring nuclei is explored within a selfconsistent Skyrme Hartree-Fock plus Bardeen-Cooper-Schrieffer approach. By using the well established SIII Skyrme parametrization, without any special adjustments related to low-energy isomer, the single-particle spectrum provided by the model reproduces the correct isomer $K^π=3/2^{+}$ spin and parity, and the relative proximity of the isomeric state to the $K^π=5/2^{+}$ ground state, yet on the keV scale. We show that this approach may provide microscopic estimates for some related observables, such as the quadrupole and octupole moments, deformation parameters as well as magnetic dipole moments. Its ability to provide a prediction for the M1 isomer transition probability is discussed. The obtained $^{229}$Th single-particle structure is compared with that provided by calculations in neighbouring actinide isotopes and isotones, allowing us to assess the more general role of the considered mechanism for the formation of low-energy isomers.
description: Accepted in Phys. Rev. C; 19 pages, 6 figures, 4 tables
Pauli-limited upper critical field in Fe1+yTe1-xSex
Creators: name: Lei, Hechang
name: Hu, Rongwei
name: Choi, E. S.
name: Warren, J. B.
name: Petrovic, C.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: In this work we investigated the temperature dependence of the upper critical field u0Hc2(T) of Fe1.02(3)Te0.61(4)Se0.39(4) and Fe1.05(3)Te0.89(2)Se0.11(2) single crystals by measuring the magnetotransport properties in stable dc magnetic fields up to 35 T. Both crystals show that u0Hc2(T) in the ab-plane and along the c-axis exhibit saturation at low temperatures. The anisotropy of u0Hc2(T) decreases with decreasing temperature, becoming nearly isotropic when the temperature T->0. Furthermore, u0Hc2(0) deviates from the conventional Werthamer-Helfand-Hohenberg (WHH) theoretical prediction values for both field directions. Our analysis indicates that the spin-paramagnetic pair-breaking effect is responsible for the temperature-dependent behavior of u0Hc2(T) in both field directions.
description: 7 pages and 6 figures
Direct Evidence for Multiferroic Magnetoelectric Coupling in 0.9BiFeO3-0.1BaTiO3
Creators: name: Singh, Anar
name: Pandey, Vibhav
name: Kotnala, R. K.
name: Pandey, Dhananjai
Publisher: name: arXiv
Year: 2008
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: Magnetic, dielectric and calorimetric studies on 0.9BiFeO3-0.1BaTiO3 indicate strong magnetoelectric coupling. XRD studies reveal a very remarkable change in the rhombohedral distortion angle and a significant shift in the atomic positions at the magnetic Tc due to an isostructural phase transition. The calculated polarization using Rietveld refined atomic positions scales linearly with magnetization. Our results provide the first unambiguous evidence for magnetoelectric coupling of intrinsic multiferroic origin in a BiFeO3 based system.
description: 14 pages including 5 figures (Accepted in PRL)
Unified Treatment of Even and Odd Anharmonic Oscillators of Arbitrary Degree
Creators: name: Jentschura, U. D.
name: Surzhykov, A.
name: Zinn-Justin, J.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: We present a unified treatment, including higher-order corrections, of anharmonic oscillators of arbitrary even and odd degree. Our approach is based on a dispersion relation which takes advantage of the PT-symmetry of odd potentials for imaginary coupling parameter, and of generalized quantization conditions which take into account instanton contributions. We find a number of explicit new results, including the general behaviour of large-order perturbation theory for arbitrary levels of odd anharmonic oscillators, and subleading corrections to the decay width of excited states for odd potentials, which are numerically significant.
description: 5 pages, RevTeX
Holography for Cosmology
Creators: name: McFadden, Paul
name: Skenderis, Kostas
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose a holographic description of four-dimensional single-scalar inflationary universes, and show how cosmological observables, such as the primordial power spectrum, are encoded in the correlation functions of a three-dimensional QFT. The holographic description correctly reproduces standard inflationary predictions in the limit where a perturbative quantization of fluctuations is justified. In the opposite limit, wherein gravity is strongly coupled at early times, we propose a holographic description in terms of perturbative large N QFT. Initiating a holographic phenomenological approach, we show that models containing only two parameters, N and a dimensionful coupling constant, are capable of satisfying the current observational constraints.
description: 5 pages; new figure displaying predicted spectral running.
Mask-Encoded Sparsification: Mitigating Biased Gradients in Communication-Efficient Split Learning
Creators: name: Zhou, Wenxuan
name: Qu, Zhihao
name: Lyu, Shen-Huan
name: Cai, Miao
name: Ye, Baoliu
Publisher: name: arXiv
Year: 2024
Subjects: subject: Machine Learning (cs.LG)
subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences

description: This paper introduces a novel framework designed to achieve a high compression ratio in Split Learning (SL) scenarios where resource-constrained devices are involved in large-scale model training. Our investigations demonstrate that compressing feature maps within SL leads to biased gradients that can negatively impact the convergence rates and diminish the generalization capabilities of the resulting models. Our theoretical analysis provides insights into how compression errors critically hinder SL performance, which previous methodologies underestimate. To address these challenges, we employ a narrow bit-width encoded mask to compensate for the sparsification error without increasing the order of time complexity. Supported by rigorous theoretical analysis, our framework significantly reduces compression errors and accelerates the convergence. Extensive experiments also verify that our method outperforms existing solutions regarding training efficiency and communication complexity.
Exploring the combination characteristics of lumefantrine, an antimalarial drug and human serum albumin through spectroscopic and molecular docking studies
Creators: name: Kabiru Abubakar Musa
name: Nor Farrah Wahidah Ridzwan
name: Saharuddin B. Mohamad
name: Tayyab, Saad
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Binding of lumefantrine (LUM), an antimalarial drug to human serum albumin (HSA), the main carrier protein in human blood circulation was investigated using fluorescence quenching titration, UV–vis absorption and circular dichroism (CD) spectroscopy as well as molecular docking. LUM-induced quenching of the protein (HSA) fluorescence was characterized as static quenching, as revealed by the decrease in the value of the Stern-Volmer quenching constant, Ksv with increasing temperature, thus suggesting LUM-HSA complex formation. This was also confirmed from the UV–vis absorption spectral results. Values of the association constant, Ka for LUM–HSA interaction were found to be within the range, 7.27–5.01 × 104 M−1 at three different temperatures, i.e. 288 K, 298 K and 308 K, which indicated moderate binding affinity between LUM and HSA. The LUM–HSA complex was stabilized by hydrophobic interactions, H-bonds, as well as van der Waals forces, as predicted from the thermodynamic data (ΔS = +50.34 J mol−1 K−1 and ΔH = −12.3 kJ mol−1) of the binding reaction. Far-UV and near-UV CD spectral results demonstrated smaller changes in both secondary and tertiary structures of HSA upon LUM binding, while three-dimensional fluorescence spectra suggested alterations in the microenvironment around protein fluorophores (Trp and Tyr). LUM binding to HSA offered stability to the protein against thermal stress. Competitive drug displacement results designated Sudlow’s Site I, located in subdomain IIA of HSA as the preferred binding site of LUM on HSA, which was well supported by molecular docking analysis. Communicated by Ramaswamy H. Sarma
Non-enzymatic glycation of human serum albumin modulates its binding efficacy towards bioactive flavonoid chrysin: A detailed study using multi-spectroscopic and computational methods
Creators: name: Sharat Sarmah
name: Somdev Pahari
name: Sourav Das
name: Belwal, Vinay Kumar
name: Madhurima Jana
name: Atanu Singha Roy
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The non-enzymatic glycation of plasma proteins by reducing sugars have important consequences on the conformational and functional properties of protein. The formation of advanced glycation end products (AGEs) is responsible for cell death and other pathological conditions. We have synthesized the glycated human serum albumin (gHSA) and characterized the same by using differential spectroscopic measurements. The aim of the present study is to determine the effect of glycation on the binding of human serum albumin (HSA) with bioactive flavonoid chrysin, which possesses anti-cancer, anti-inflammatory and anti-oxidant activities. The interaction of chrysin with HSA and gHSA was studied using multi-spectroscopic, molecular docking and molecular dynamics (MD) simulation techniques. Chrysin quenched the intrinsic fluorescence of both HSA and gHSA by static quenching mechanism. The value of the binding constant (Kb) for the interaction of HSA-chrysin complex (4.779 ± 0.623 × 105 M-1 at 300 K) was found to be higher than that of gHSA-chrysin complex (2.206 ± 0.234 × 105 M-1 at 300 K). Hence, non-enzymatic glycation of HSA significantly reduced its binding affinity towards chrysin. The % α-helicity of HSA was found to get enhanced upon binding with chrysin, and minimal changes were observed for the gHSA-chrysin complex. Site marker probe studies indicated that chrysin binds to subdomain IIA and IIIA of both HSA and gHSA. The results from molecular docking and MD simulation studies correlated well with the experimental findings. Electrostatic interactions followed by hydrogen bonding and hydrophobic interactions played major roles in the binding process. These observations may have some useful insights into the field of pharmaceutics.
Identifying the key residues instrumental in imparting stability to amyloid beta protofibrils – a comparative study using MD simulations of 17-42 residues
Creators: name: Dutta, Madhu Sudan
name: Soumalee Basu
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Extracellular plaques, the hallmark of Alzheimer’s disease brains, consist of insoluble amyloid fibrils that result from the aggregation of amyloid beta peptides. None of the few therapeutic options currently adopted, address the cause of the disease. Instead, they reduce symptom of the disease. Inhibition of aggregation or destabilization of aggregates therefore, emerges as a preferable therapeutic approach. Designing inhibitors or destabilizers demands comprehensive knowledge of the residues of amyloid beta responsible for the phenomenal structural stability of the aggregate. For the purpose, we have compared the effect on structural destabilization of 13 in silico mutations (single and double) with the wild type counterpart of beta-strand-turn-beta-strand motif of the amyloid beta protofibrils by molecular dynamics simulation. Besides the already known salt bridge interaction between K28 and D23, our analyses expose more significant role of K28 as the only positive charge present in the vicinity. Amongst the two consecutive aromatic residues, F19 is involved in stacking interaction; although effect of F20 mutation is more pronounced. Face to face arrangement of A21 and V36 acts as a pillar maintaining the necessary optimum distance between consecutive chains to promote stabilizing interactions. In addition to providing stability to the first beta-strand, large sized negatively charged E22 facilitates salt bridge formation by ensuring fixed relative position of D23 and in turn K28. Likewise, the hydrophobic residues I32 and L34 pack the protofibril core, once again fostering salt bridge interaction. Prospectively, these findings may be compiled for efficient identification or design of scaffolds accountable for protofibril destabilization.
SDSS J094533.99+100950.1 - the remarkable weak emission line quasar
Creators: name: Hryniewicz, Krzysztof
name: Czerny, Bozena
name: Nikolajuk, Marek
name: Kuraszkiewicz, Joanna
Publisher: name: arXiv
Year: 2009
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: Weak emission line quasars are a rare and puzzling group of objects. In this paper we present one more object of this class found in the Sloan Digital Sky Survey (SDSS). The quasar SDSS J094533.99+100950.1, lying at z = 1.66, has practically no C IV emission line, a red continuum very similar to the second steepest of the quasar composite spectra of Richards et al., is not strongly affected by absorption and the Mg II line, although relatively weak, is strong enough to measure the black hole mass. The Eddington ratio in this object is about 0.45, and the line properties are not consistent with the trends expected at high accretion rates. We propose that the most probable explanation of the line properties in this object, and perhaps in all weak emission line quasars, is that the quasar activity has just started. A disk wind is freshly launched so the low ionization lines which form close to the disk surface are already observed but the wind has not yet reached the regions where high ionization lines or narrow line components are formed. The relatively high occurrence of such a phenomenon may additionally indicate that the quasar active phase consists of several sub-phases, each starting with a fresh build-up of the Broad Line Region.
description: 10 pages, 3 figures, 5 tables; accepted for publication in MNRAS
Sidgwick, Reflective Equilibrium and the Triviality Charge
Creators: name: Schmidt, Michael W.
Publisher: name: KIT Scientific Publishing
Year: 2021

description: I argue against the claim that it is trivial to state that Sidgwick used the method of wide reflective equilibrium. This claim is based on what could be called the Triviality Charge, which is pressed against the method of wide reflective equilibrium by Peter Singer. According to this charge, there is no alternative to using the method if it is interpreted as involving all relevant philosophical background arguments. The main argument against the Triviality Charge is that although the method of wide reflective equilibrium is compatible with coherentism (understood as a form of weak foundationalism) as well as moderate foundationalism, it is not compatible with strong foundationalism. Hence, the claim that a philosopher uses the method of wide reflective equilibrium is informative. In particular, this is true with regard to Sidgwick.
LINGUISTIC ASSESSMENT OF THE MAIN DIFFERENCES BETWEEN SPOKEN AND WRITTEN LANGUAGE
Creators: name: Kholmatova, Barnokhon
Publisher: name: Zenodo
Year: 2025

description: This article examines the key differences between spoken and written language from a linguistic perspective, exploring various features such as syntax, morphology, pragmatics, and discourse. The study emphasizes that while both forms of communication serve the same basic purpose of conveying meaning, they differ significantly in structure, function, and context. Spoken language is found to be more spontaneous, informal, and context-dependent, relying on immediate interaction and non-verbal cues. In contrast, written language is more structured, formal, and coherent, designed for a broader audience and lacking the immediate feedback that spoken communication provides. The article analyzes these differences through a comparative approach, highlighting how each form is shaped by its specific cognitive and social functions. These distinctions are essential for linguists, educators, and communicators to understand as they shape the way we process and produce language.
Lichens in Diverse Landscapes: EREN-NEON Flexible Learning Project
Creators: name: Garneau, Danielle
name: Heard, Matthew
name: Kolozsvary, Mary
Publisher: name: QUBES Educational Resources
Year: 2020

description: This project makes use of publicly-available datasets on lichen presence and abundance and wet deposition, paired with geospatial data on air quality, tree canopy cover, and locally collected field data, to better understand how lichens respond to changes
Geometria e metodo tra Cartesio e Spinoza
Geometry and method between Descartes and Spinoza
Creators: name: Baggi, Paolo Giovanni <1982>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2013
Subjects: M-FIL/01 Filosofia teoretica

description: Il testo che segue è, in primo luogo, una lettura del Tractatus de intellectus emendatione di Spinoza. Tra i tanti filtri che potevano caratterizzare la lettura di quest'opera, quello che si è adottato ha avuto lo scopo di far emergere nei suoi tratti fondamentali la distanza tra l'approccio spinoziano al problema della conoscenza e del metodo per il suo raggiungimento e l'approccio cartesiano.
description: The text that follows is, first, a reading of the Tractatus de intellectus emendatione of Spinoza. Among the many filters that were able to characterize the reading of this work, one that has been adopted had the purpose of bringing out in its basic distance the approach of Spinoza and Descartes to the problem of knowledge and method.
Quasinormal resonances of near-extremal Kerr-Newman black holes
Creators: name: Hod, Shahar
Publisher: name: arXiv
Year: 2008
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Astrophysics (astro-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study analytically the fundamental resonances of near-extremal, slowly rotating Kerr-Newman black holes. We find a simple analytic expression for these black-hole quasinormal frequencies in terms of the black-hole physical parameters: omega=m Omega-2i pi T(l+1+n), where T and Omega are the temperature and angular velocity of the black hole. The mode parameters l and m are the spheroidal harmonic index and the azimuthal harmonic index of a co-rotating mode, respectively. This analytical formula is valid in the regime Im omega << Re omega <<1/M, where M is the black-hole mass.
description: 4 pages
Entanglement enhanced bit rate over multiple uses of a lossy bosonic channel with memory
Creators: name: Lupo, Cosmo
name: Mancini, Stefano
Publisher: name: arXiv
Year: 2009
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a study of the achievable rates for classical information transmission via a lossy bosonic channel with memory, using homodyne detection. A comparison with the memoryless case shows that the presence of memory enhances the bit rate if information is encoded in collective states, i.e. states which are entangled over different uses of the channel.
description: 3 figures, comments are welcome