cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Wider Boundaries of Daring: The Modernist Impulse in Canadian Women's Writing, eds. Di Brandt and Barbara Godard
Creators: name: Brannagan Frederiksen, Melanie
Publisher: name: Prairie Fire Press, Inc.
Year: 2011
Subjects: non-fiction; modernist women poets; literary criticism; canadian literary history; modernism; brandt; godard

description: Prairie Fire Review of Books, Vol 10, No 4 (2010)
Supplemental Material, sj-pdf-1-mrj-10.1177_0022243720986546 - How Life-Role Transitions Shape Consumer Responses to Brand Extensions
Creators: name: Su, Lei
name: Alokparna (Sonia) Basu Monga
name: Yuwei Jiang
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150402 Hospitality Management
subject: FOS: Economics and business

description: Supplemental Material, sj-pdf-1-mrj-10.1177_0022243720986546 for How Life-Role Transitions Shape Consumer Responses to Brand Extensions by Lei Su, Alokparna (Sonia) Basu Monga and Yuwei Jiang in Journal of Marketing Research
Additional file 1 of On the use of prior distributions in bayesian inference applied to Ecology: an ecological example using binomial proportions in exotic plants, Central Chile
Creators: name: Bustamante, Ramiro O.
name: Iturriaga, Andrés
name: Flores-Alvarado, Sandra
name: García, Rafael A.
name: Goncalves, Estefany
Publisher: name: figshare
Year: 2024
Subjects: subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Science Policy
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1.
sj-pdf-1-imr-10.1177_03000605211002083 - Supplemental material for Tocilizumab has no direct effect on cell lines infected with human T-cell leukemia virus type 1
Creators: name: Yushiro Endo
name: Fukui, Shoichi
name: Koga, Tomohiro
name: Sasaki, Daisuke
name: Hasegawa, Hiroo
name: Yanagihara, Katsunori
name: Okayama, Akihiko
name: Nakamura, Tatsufumi
name: Kawakami, Atsushi
name: Nakamura, Hideki
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-imr-10.1177_03000605211002083 for Tocilizumab has no direct effect on cell lines infected with human T-cell leukemia virus type 1 by Yushiro Endo, Shoichi Fukui, Tomohiro Koga, Daisuke Sasaki, Hiroo Hasegawa, Katsunori Yanagihara, Akihiko Okayama, Tatsufumi Nakamura, Atsushi Kawakami and Hideki Nakamura in Journal of International Medical Research
Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy
Creators: name: Tang, J
name: Wu, Y
name: Mahler, S.M
name: Xu, Z.P
name: Thurecht, K.J
name: Huang, L
name: Li, B
name: Howard, C.B
Publisher: name: Elsevier Ltd
Year: 2019

description: Combined and targeted therapy have been extensively employed to achieve more effective elimination of tumor tissues. In this study, biocompatible multifunctional lipid-coated calcium phosphate nanoparticles (LCP NPs) were designed and constructed as an efficient targeted delivery system for combined gene/photothermal therapy to inhibit growth of the triple negative breast tumor (MDA-MB-468) in vitro and in vivo. LCP NPs were functionalized with a bispecific antibody (BsAb) via non-covalent bond specific for methoxy group of PEG (mPEG) on the particle surface. This BsAb is also able to target epidermal growth factor receptor (EGFR) expressed on MDA-MB-468 cells. Such LCP-BsAb NPs loaded with Cell Death (CD)-siRNA and indocyanine green (ICG) were efficiently taken up by MDA-MB-468 cells, significantly inducing cell apoptosis and synergistically suppressing cell proliferation upon irradiation of 808 nm near-infrared laser. These targeted multifunctional LCP NPs more efficiently accumulated in the tumor tissue. The combined RNAi (CD-siRNA) and photothermal (ICG) therapy using the targeted LCP NPs nearly eliminated both small tumors (∼100 mm3) and large tumors (∼500 mm3) in the mouse model. Thus, the well-devised multifunctional LCP NPs are one of the most promising delivery systems for combined and targeted cancer therapy.
The Alpha-H5N1 Virus and Species-Level Extinction Risk Posed by HPAI-Caused Mortality to California Condors
Creators: name: Grossner, Emma
name: Grossner, Emma
Publisher: name: Humanities Commons
Year: 2024

description: Completed & Submitted for Publication Research Article concerning the  Alpha-H5N1 Virus and the Species-Level Extinction Risk It Poses by HPAI-Caused Mortality to California Condors(Gymnogyps californianus) in conjunction with Dr. Candace Bennett, Washington State Dept. Fish & Wildlife & Senior Research Advisor Michael Morelli, M.A.
MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data
Creators: name: Perou, C.M
name: Garay, J.P
name: Marron, J.S
name: Liu, S
name: Thennavan, A
Publisher: name: BioMed Central Ltd
Year: 2021

description: Single-cell RNA sequencing (scRNA-seq) provides new opportunities to characterize cell populations, typically accomplished through some type of clustering analysis. Estimation of the optimal cluster number (K) is a crucial step but often ignored. Our approach improves most current scRNA-seq cluster methods by providing an objective estimation of the number of groups using a multi-resolution perspective. MultiK is a tool for objective selection of insightful Ks and achieves high robustness through a consensus clustering approach. We demonstrate that MultiK identifies reproducible groups in scRNA-seq data, thus providing an objective means to estimating the number of possible groups or cell-type populations present.
sj-pdf-2-imr-10.1177_0300060521999531 - Supplemental material for Robert’s uterus with delayed diagnosis and potential consequences: a case report
Creators: name: Zhang, Jing
name: Zhou, Weili
name: Tang, Ying
name: Tan, Shiqiao
name: Qiao, Lin
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Dentistry not elsewhere classified
subject: Emergency Medicine
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Nursing not elsewhere classified
subject: Nutrition and Dietetics not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Orthopaedics
subject: Sports Medicine
subject: Otorhinolaryngology
subject: Aged Health Care
subject: Paediatrics
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Public Health and Health Services not elsewhere classified
subject: Respiratory Diseases
subject: Sociological Methodology and Research Methods
subject: Surgery

description: Supplemental material, sj-pdf-2-imr-10.1177_0300060521999531 for Robert’s uterus with delayed diagnosis and potential consequences: a case report by Jing Zhang, Weili Zhou, Ying Tang, Shiqiao Tan and Lin Qiao in Journal of International Medical Research
Additional file 1 of The impact of applying various de novo assembly and correction tools on the identification of genome characterization, drug resistance, and virulence factors of clinical isolates using ONT sequencing
Creators: name: Safar, Hussain A.
name: Alatar, Fatemah
name: Nasser, Kother
name: Al-Ajmi, Rehab
name: Alfouzan, Wadha
name: Mustafa, Abu Salim
Publisher: name: figshare
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1: Table S1. Accession numbers of read sets. Table S2. Overview of the sequencing run. Table S3. Nanoplot statistics before and after filtering. Table S4. Benchmark the running time and CPU usage of read trimming, assembly, read correction, quality control and tertiary analysis tools. Table S5. MLST prediction by staramr.
Nano Codelivery of Oxaliplatin and Folinic Acid Achieves Synergistic Chemo-Immunotherapy with 5-Fluorouracil for Colorectal Cancer and Liver Metastasis
Creators: name: Huang, L
name: Das, M
name: Yu, Z
name: Guo, J
Publisher: name: NLM (Medline)
Year: 2020

description: FOLFOX, the combinational strategy of folinic acid (FnA), 5-fluorouracil (5-Fu), and oxaliplatin (OxP), has been used as standard treatment of colorectal cancer (CRC) for decades. Despite the improved survival, patients still suffer from drawbacks such as low efficacy, high toxicity, and long course of treatment. New strategies to address these issues are needed to further clinical benefits. In this study, a nanoprecipitate (C26H35N9O7Pt) was formed by the active form of OxP ([Pt(DACH)(H2O)2]2+) and FnA, which was formulated into an aminoethyl anisamide targeted PEGylated lipid nanoparticle within microemulsions using nanoprecipitation technique. The resultant formulation (namely Nano-Folox) significantly promoted the blood circulation and tumor accumulation of platinum drug and FnA in an orthotopic CRC mouse model. Emerging evidence indicates that OxP can not only provide anticancer cytotoxic effects but also induce immunogenic cell death (a type of apoptosis that primes anticancer immune responses). Consequently, Nano-Folox demonstrated favorable chemo-immunotherapeutic activities in orthotopic CRC mice. In addition, when compared to FOLFOX the significantly stronger chemo-immunotherapeutic responses were achieved by the combination of Nano-Folox and 5-Fu without showing toxicity. Moreover, the anti-PD-L1 monoclonal antibody enhanced Nano-Folox/5-Fu for decreased liver metastases in mice. These results indicate the potential of Nano-Folox-based combination strategy for the treatment of CRC.
Antioxidant and Anti-Aging Effects of Aquilaria crassna Heartwood Ethanol Extract in Saccharomyces cerevisiae
Creators: name: Senabunyarith, Apinan
name: Alugoju, Phaniendra
name: Chuchawankul, Siriporn
name: Tencomnao, Tewin
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description:  Aquilaria crassna, a medicinal plant, has long been used in traditional medicine for its remarkable health benefits. This study investigated the anti-aging effects of Aquilaria crassna Heartwood Ethanol Extract (ACHEE) in yeast Saccharomyces cerevisiae. ACHEE improved yeast’s chronological lifespan by reducing levels of reactive oxygen species, improving mitochondrial membrane potential, and decreasing apoptosis. The mRNA expression levels of TOR1 and SCH9 genes were lowered, while those of RIM15 and SIR2 genes were increased upon treatment with extract. Together with molecular docking analysis, the findings suggest ACHEE exerts anti-aging effects via modulating antioxidant and nutrient sensing pathways.
sj-pdf-1-jcb-10.1177_0271678X211002297 - Supplemental material for Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain
Creators: name: Diaz, Ariel
name: Merino, Paola
name: McCann, Patrick
name: Yepes, Manuel A
name: Quiceno, Laura G
name: Torre, Enrique
name: Tomkins, Amelia
name: Zhang, Xiaodong
name: Hales, Chadwick M
name: Tong, Frank C
name: Yepes, Manuel
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Emergency Medicine
subject: Endocrinology
subject: Medicine
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: Biological Sciences not elsewhere classified
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X211002297 for Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain by Ariel Diaz, Paola Merino, Patrick McCann, Manuel A Yepes, Laura G Quiceno, Enrique Torre, Amelia Tomkins, Xiaodong Zhang, Chadwick M Hales, Frank C Tong and Manuel Yepes in Journal of Cerebral Blood Flow & Metabolism
Enamelled copper-alloy ring brooch
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: Roman ring brooch, overall diam. 3.5cm. Consists of a cast recessed ring, with open centre, inlaid with red and pale green (or perhaps originally white) enamel in wedges, but much deteriorated. Around the edge cast in one with ring, are 5 lobes (originally 6 - one knocked off in antiquity and break worn) which have likewise had enamel in them. The colour now is orange, and may be original. One lug more solid and setting smaller - behind it is the double pierced lug attachment for the pin coil. On the opposite lug are the remains of the catchpate. Pin missing.
Supplemental Material, sj-docx-2-ear-10.1177_01455613211006010 - Montgomery T-Tube Insertion Under ECMO in a Patient With Complete Subglottic Stenosis and Severe Lower Tracheal Collapse
Creators: name: Jin, Beibei
name: Wang, Ting
name: Wang, Yuling
name: Zhang, Jie
Publisher: name: SAGE Journals
Year: 2021
Subjects: Otorhinolaryngology

description: Supplemental Material, sj-docx-2-ear-10.1177_01455613211006010 for Montgomery T-Tube Insertion Under ECMO in a Patient With Complete Subglottic Stenosis and Severe Lower Tracheal Collapse by Beibei Jin, Ting Wang, Yuling Wang and Jie Zhang in Ear, Nose & Throat Journal
Additional file 1 of Providing a model for financing the treatment costs during biological crises using the fiscal space development approach
Creators: name: Yaghoubi, Maryam
name: Vahedi Idehlo, Masoud
name: mehdizadeh, Parisa
name: Meskarpour Amiri, Mohammad
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Appendix A
Feelings without Structure: A Cultural Materialist View of Affective Politics
Creators: name: Pittel, Harald
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: Refugees
subject: Alternative für Deutschland (Political party)
subject: Williams, Raymond
subject: Merkel, Angela, 1954-
subject: Political science
subject: FOS: Political science
subject: Sociology
subject: FOS: Sociology

description: The term ‘affective politics’ is sometimes used to dismiss political strategies as being directed merely at affects at the expense of rational analysis (Massumi 2015: 65f). While such uses are meant to criticize certain politics, appeals to the affects – and consequently, forms of propaganda or populism – do not have to be bad at all. The point here is that affects not only play a role for manipulative governments or populist movements, but are a crucial factor for the political in general, which in a post-modern world can no longer be naïvely understood as being grounded in nature or reason (Massumi 2015: VIIIf). So, if politics are always entangled with affects, when do political affects become problematic? This article will suggest that cultural materialism offers a few concepts that we can draw on to differentiate acceptable from harmful kinds of affective politics. More specifically, I am going to encourage a new reading of Raymond Williams’ concept of the structure of feeling and the way it is transformed in his later appropriation of Gramsci’s theory of hegemony.
Additional file 1 of TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle
Creators: name: Jiang, Yi
name: Zhu, Chao
name: Huang, Haoxuan
name: Huang, Gaomin
name: Fu, Bin
name: Xi, Xiaoqing
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 1
Ethnomedicinal Uses of the Flora as an Alternative During the Treatment of SARS-CoV-2 in the Mayan Communities of the Yucatan Peninsula, Mexico
Creators: name: Ríos-Oviedo, Ángel
name: Cetzal-Ix, William
name: López-Castilla, Héctor M. J.
name: Basu, Saikat Kumar
name: Tamayo-Cen, Iván
name: De la Torre Espinosa, Zamaria
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: The importance of ethnomedicinal studies on the flora of the Yucatan Peninsula (YP) has been of great relevance for the treatment of SARS-CoV-2 virus. The demand for the drugs to treat the SARS-CoV-2 that caused the COVID-19 pandemic impacted globally. The objective of this work has been to analyze the medicinal plants of YP, Mexico, used as phytopharmaceuticals in 2020–2021 to treat pre- and post-symptoms of SARS-CoV-2. A total of 28 species of plants representing 23 families were record. A total of 336 bioactive compounds were found that are related to medicinal properties
sj-pdf-1-imr-10.1177_0300060521993965 - Supplemental material for Multidisciplinary team management of 46,XY 17α-hydroxylase deficiency: a case report and literature review
Creators: name: Zhou, Yang
name: Xue, Xue
name: Shi, Panpan
name: Lu, Qinrui
name: Lv, Shulan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Health and Community Services
subject: Cardiology
subject: Dentistry not elsewhere classified
subject: Emergency Medicine
subject: Endocrinology
subject: Geriatrics and Gerontology
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Nursing not elsewhere classified
subject: Nutrition and Dietetics not elsewhere classified
subject: Oncology and Carcinogenesis not elsewhere classified
subject: Orthopaedics
subject: Sports Medicine
subject: Otorhinolaryngology
subject: Aged Health Care
subject: Paediatrics
subject: Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: Psychology not elsewhere classified
subject: Psychiatry (incl. Psychotherapy)
subject: Public Health and Health Services not elsewhere classified
subject: Respiratory Diseases
subject: Sociological Methodology and Research Methods
subject: Surgery

description: Supplemental material, sj-pdf-1-imr-10.1177_0300060521993965 for Multidisciplinary team management of 46,XY 17α-hydroxylase deficiency: a case report and literature review by Yang Zhou, Xue Xue, Panpan Shi, Qinrui Lu and Shulan Lv in Journal of International Medical Research
"RUUSUL-MASAIL" ASARIDA ZIKR QILINGAN HANAFIY VA SHOFEIY MAZHABLARIDAGI IXTILOFLI MASALALAR
Creators: name: Saidjalolov, S.S.
name: Nabiyeva, Muazzamoy
Publisher: name: Zenodo
Year: 2024

description: Mahmud Zamaxshariy Movarounnahrdan chiqqan buyuk mufassir, mutakallim, huquqshunos. Movarounnahrda ilmiy, madaniy va iqtisodiy ahvol tanazzulga yuz tutgan paytda Mahmud Zamaxshariy fidoyi olimlar bilan ilm-fanni tiklash va tiklashga xizmat qildi. Uning o‘nta asari bugun ma’lum bo‘lib, bu asarlar ustidagi ilmiy izlanishlar to‘xtovsiz davom etmoqda.
Evaluating the traditional wisdom of medicinal plants in Suhelwa Wildlife Sanctuary, India
Creators: name: Ojha, Anju Kumari
name: Bala, Chandra
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Plant Biology

description: This study explores tradition healers’ knowledge of wild medicinal plants in Suhelwa Wildlife Sanctuary, India. A total of 137 plant species, belonging to 55 families, were documented by semi structured interview with 72 informants. Notably, Fabaceae (11.68%) and Poaceae (9.56%) were the most prominent families. The leaves were dominantly used from 77 species (54.74%) in herbal preparation. The study revealed herbaceous life form (44%) being the mostly used in ethnomedicine. The ICF value ranged from 0.86 to 0.96 with maximum value for digestive disease category (0.96). This enriched database can serve as a springboard for future pharmacological research.
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis
Creators: name: Bowen, J
name: Silverstein, J.
name: AURORA US Network
name: Sanders, M.E
name: Laird, P.W.
name: Perou, C.M.
name: McClure, M.B
name: Xia, Y
name: Wheeler, G.L
name: Hoadley, K.A.
name: Garcia-Recio, S
name: Wheless, A
name: Parker, J.S
name: Isaacs, C.
name: Ropelewski, A.
name: Kelly, B.J
name: Lin, N.U
name: Fan, C
name: King, T.A.
name: Davidson, N.E.
name: Krop, I
name: Davis, M.
name: Couch, F.J.
name: Carey, L.A.
name: Foy, K.K
name: Garrido-Castro, A.C
name: Park, B.H
name: Chandran, U.
name: Coppens, S
name: Garrett, A.L
name: Balko, J.M.
name: Rajkovic, A
name: De Cubas, A.A.
name: Anders, C
name: Hilsenbeck, S.G.
name: Burns, R.T
name: Rezk, S
name: Symmans, W.F.
name: Creighton, C.J
name: Shen, H
name: Norton, L.
name: Liu, M.C.
name: Wolff, A.C.
name: Smith, M.A
name: Felsheim, B.M
name: De Cubas, A.A
name: Nanda, R
name: Hinoue, T
name: Richardson, A.L.
name: Storniolo, A.M.
name: Lee, A.V.
name: Mardis, E.R.
name: Marcom, P.K.
name: Rimawi, M.F
name: Leraas, K
name: Karaesmen, E
name: Gastier-Foster, J
name: Ericsson, P.I.G
name: Pascual, T
Publisher: name: Nature Research
Year: 2023

description: The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic breast cancer (51 primary cancers and 102 metastases) by RNA sequencing, tumor/germline DNA exome and low-pass whole-genome sequencing and global DNA methylation microarrays. Expression subtype changes were observed in ~30% of samples and were coincident with DNA clonality shifts, especially involving HER2. Downregulation of estrogen receptor (ER)-mediated cell–cell adhesion genes through DNA methylation mechanisms was observed in metastases. Microenvironment differences varied according to tumor subtype; the ER+/luminal subtype had lower fibroblast and endothelial content, while triple-negative breast cancer/basal metastases showed a decrease in B and T cells. In 17% of metastases, DNA hypermethylation and/or focal deletions were identified near HLA-A and were associated with reduced expression and lower immune cell infiltrates, especially in brain and liver metastases. These findings could have implications for treating individuals with metastatic breast cancer with immune- and HER2-targeting therapies.
Belonging, Groups & Identity - Baumeister, Tania Singer-empathy, Solomon Asch's (authority experiment), Hogg & Abrams theory of subjective uncertainty reduction & the Ideology of Enlightenment + Prism Paradigm & spirituality as "natural predisposition"
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2008
Subjects: subject: Indian philosophy
subject: Hinduism
subject: Spirituality
subject: Belonging (Social psychology)
subject: Theology, Doctrinal
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Social cognitive theory
subject: Filipinos--Psychology
subject: Manners and customs

description: As the prominent social psychologists, Baumeister and Leary, point out, "Groups can share food, provide mates, and help care for offspring (including orphans). Some survival tasks such as hunting large animals or maintaining defensive vigilance against predatory enemies, are best accomplished by group cooperation…. Competition for limited resources could also provide a powerful stimulus to forming interpersonal connections." (p.499 need) The need to belong is deeply rooted in human consciousness. Baumeister emphasizes that the need to belong is a powerful need, and not just a want. While people can go for long periods of time abstaining from sex without dire consequences, the absence of social interaction can have lethal consequences. "One very important motivation that lies on the boundary between natural and cultural motivations is the need to belong to social groups. It is apparent that people have a deeply rooted need to have contact with other people." (p14 Meanings) "We [Baumeister and Leary] suggest that belongingness can be almost as compelling a need as food and that human culture is significantly conditioned by the pressure to provide belongingness."(p 498 need)
Additional file 1 of Similar cortical morphometry trajectories from 5 to 9 years in children with perinatal HIV who started treatment before age 2 years and uninfected controls
Creators: name: Nwosu, Emmanuel C.
name: Holmes, Martha J.
name: Cotton, Mark F.
name: Dobbels, Els
name: Little, Francesca
name: Laughton, Barbara
name: van der Kouwe, Andre
name: Robertson, Frances
name: Meintjes, Ernesta M.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Table S1. Regression coefficients from a linear mixed effect analysis examining effects of HIV status on KABC developmental trajectories from age 7 to 9 years. Table S2. Regression coefficients from a post-hoc LME analysis of CT trajectories in regions where CPHIV showed cortical thickening using only children who provided data at more than one time point (N=85; 52 PHIV). Numbering of regression coefficients is as per equation (2). Table S3. Regression coefficients from a post-hoc LME analysis comparing CT developmental trajectories between CHEU and CHU in the 6 regions where children with PHIV demonstrated thicker cortex from age 5 to 9 years than HIV- controls. Numbering of regression coefficients is as per equation (2). Table S4. Regression coefficients from a post-hoc LME analysis comparing CT developmental trajectories between CPHIV in whom treatment was interrupted and those on continuous ART in the 6 regions where children with PHIV demonstrated thicker cortex from age 5 to 9 years than HIV- controls. Numbering of regression coefficients is as per equation (2). Figure S1. Effects of HIV status (HIVE vs HIV-) by age interactions on local gyrification indices (LGIs). (A) Colour map of effects sizes. Positive regression coefficients (red/yellow) indicate greater rates of change of LGI in children who had previously been diagnosed with HIVE than HIV-, and negative coefficients (cyan/blue) indicate lower rates of change in HIVE than HIV- children. The colour bar scale applies to both lateral (top) and medial (bottom) views. Children with a previous diagnosis of HIVE did not demonstrate the increasing gyrification from ages 5 to 9 years evident in HIV- controls in bilateral rostral middle frontal regions. In the left hemisphere in the region outlined in red (white arrow), the difference is significant at an FDR-corrected p<0.05. (B) Plots showing the rate of change of gyrification in the left rostral middle frontal regions from ages 5 and 9 across HIVE and HIV- groups (left) and a spaghetti plot of individual trajectories (right). (HIV- = 66, HIVE = 12).
Belonging, Groups & Identity - Baumeister, Tania Singer-empathy, Solomon Asch's (authority experiment), Hogg & Abrams  theory of subjective uncertainty reduction & the Ideology of Enlightenment + Prism Paradigm & spirituality as "natural predisposition"
Creators: name: Peck Jr, Charles
Publisher: name: Humanities Commons
Year: 2008
Subjects: subject: Belonging (Social psychology)
subject: Social cognitive theory
subject: Manners and customs
subject: Philosophy
subject: FOS: Philosophy, ethics and religion
subject: Theology, Doctrinal
subject: Indian philosophy
subject: Filipinos--Psychology
subject: Hinduism
subject: Spirituality

description: As the prominent social psychologists, Baumeister and Leary, point out, “Groups can share food, provide mates, and help care for offspring (including orphans). Some survival tasks such as hunting large animals or maintaining defensive vigilance against predatory enemies, are best accomplished by group cooperation…. Competition for limited resources could also provide a powerful stimulus to forming interpersonal connections.” (p.499 need) The need to belong is deeply rooted in human consciousness. Baumeister emphasizes that the need to belong is a powerful need, and not just a want. While people can go for long periods of time abstaining from sex without dire consequences, the absence of social interaction can have lethal consequences. “One very important motivation that lies on the boundary between natural and cultural motivations is the need to belong to social groups. It is apparent that people have a deeply rooted need to have contact with other people.” (p14 Meanings) “We [Baumeister and Leary] suggest that belongingness can be almost as compelling a need as food and that human culture is significantly conditioned by the pressure to provide belongingness.”(p 498 need)
Nano-delivery of Gemcitabine Derivative as a Therapeutic Strategy in a Desmoplastic KRAS Mutant Pancreatic Cancer
Creators: name: Das, M
name: Huang, L
name: Li, J
name: Bao, M
Publisher: name: Springer
Year: 2020

description: Pancreatic ductal adenocarcinoma remains one of the challenging malignancies to treat, and chemotherapy is the primary treatment strategy available to most patients. Gemcitabine, one of the oldest chemotherapeutic drugs approved for pancreatic cancer, has limited efficacy, due to low drug distribution to the tumor and chemoresistance following therapy. In this study, we delivered gemcitabine monophosphate using lipid calcium phosphate nanoparticles, to desmoplastic pancreatic tumors. Monophosphorylation is a critical, rate-limiting step following cellular uptake of gemcitabine and precursor of the pharmacologically active gemcitabine triphosphate. Our drug delivery strategy enabled us to achieve robust tumor regression with a low parenteral dose in a clinically relevant, KRAS mutant, syngeneic orthotopic allograft, lentivirus-transfected KPC cell line-derived model of pancreatic cancer. Treatment with gemcitabine monophosphate significantly increased apoptosis of cancer cells, enabled reduction in the proportion of immunosuppressive tumor-associated macrophages and myeloid-derived suppressor cells, and did not increase expression of cancer stem cell markers. Overall, we could trigger a strong antitumor response in a treatment refractory PDAC model, while bypassing critical hallmarks of gemcitabine chemoresistance.
Additional file 1 of Relationship between disability and psychiatric outcome in multiple sclerosis patients and its determinants
Creators: name: Hassan, Shady Safwat
name: Darwish, Esam S.
name: Ahmed, Gellan K.
name: Azmy, Samah R.
name: Haridy, Nourelhoda A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Mental Health
subject: Computational Biology

description: Additional file 1. Supplemental Data. Table S1. Correlation of EDSS, psychometric scales score and other parameters. Table S2. Multivariate linear regression for EDSS with other parameters. Table S3. Multivariate linear regression for anxiety with other parameters. Table S4. Multivariate linear regression for depression with other parameters. Table S5. Multivariate linear regression for sleep with other parameters. Table S6. Multivariate linear regression for brief psychotic scale with other parameters.
Copper-alloy gilt ?reused ?harness fitting
Creators: name: Hamerow, Helena
Publisher: name: University of Oxford
Year: 2021
Subjects: Archaeology

description: Bronze-gilt disc, perhaps a horse-trapping, re-used as brooch? Diam. 4.6 cm. Cast as a solid disc with plain bronze rim and (broken) rect. loop at top. At back 1 central rivet and one at centre bottom. Traces of rivet removed at top and on one side, on the other a patch has been run in (liquid bronze) to plug a hole perhaps from another rivet. No real trace of brooch fastenings, unless the two surviving rivets were left deliberately and in some way re-used to secure a pin. The front decorated with very fine Style II ornament in chip carving technique. Plain bronze roundel in centre, flat and obviously imitating a garnet, surrounded by chip-carved gilded ridge. Between this and rim a gilded zone of Style II work: four ribbon animals in pursuit and interlinked. Each has a head with eye, obtuse angled squared 'helmet' with upcurled lower end, detached jaw biting own doubled body, jaws then crossing each other and lower jaw biting across loop of next animal body. Body triple stranded. Neck curving down and under next one's lower jaw, over own lower jaw and under upper, and continuing to terminate in bent leg with oval hip and 4 toed claw, which rests upside down against rim close to creature's own head. A curious single feature bends and angles up and across above creature's head from behind, and this may be the foreleg. Technically very well executed. Only errors are that occasionally the animal has one-strand loop. N.B. Bronze rim at centre shows traces of tinning. Gilding very thick and bright.See Fern 2005 for similar finds. – B.B.
La mort est le fruit de votre imagination: sophisme défininiste en tant que stéréotype inadapté: "la spiritualité est irréelle" - étant au-delà de toute mesure [Miller et Thompson] - Filtrage - W James - Critique approuvée Drs Koenig, Wong,, Farra,
Creators: name: Peck Jr, Charles
Publisher: name: Humanities Commons
Year: 2008
Subjects: subject: Spiritual life
subject: Spirituality--Christianity
subject: Spirituality
subject: Philosophy, French
subject: Logic
subject: Science--Methodology
subject: Naturalistic fallacy
subject: Science
subject: Mannheim, Karl, 1893-1947
subject: Ideology

description: Pourquoi un sophisme est-il important ? Bouddha dit que « nous devenons ce que nous pensons ». Hier, je parlais à un diplômé philippin (je séjourne actuellement à Gneral Santos, aux Philippines). J'ai évoqué le principal argument martérialiste tel qu'expliqué par MIller et Thompson dans un article publié sur le site Web du NIH - Pubmed - qui affirme que la spiritualité n'est pas mesurable - et n'existe donc pas. Elle a dit - "Oh oui, c'est vrai!" J'ai demandé ce qu'il en était de la compassion ? Elle a dit que la spiritualité de la compassion n'est pas mesurable. J'ai souligné que des études génétiques sur l'empathie avaient été faites et qu'une étude sur la spiritualité de la compassion avait été faite avec des résultats positifs. Ensuite, il y a l'étude sur la spiritualité des autistes réalisée par le Dr Visuri, ainsi qu'un grand nombre d'études réalisées sur la spiritualité de la musique. J'ai poursuivi en disant - si vous suivez cette ligne pour raisonner la "mort" - ce qui est bien au-delà de la mesure ou de la quantification est alors un non-sens et un produit de votre imagination. Elle était d'accord avec mon argument là-dessus.  Un extrait  - Approbations et qualifications : 1. Le Dr Paul Wong : auteur, chercheur et théoricien éminent, ainsi qu'un psychologue existentiel-positif a déclaré à propos de cet essai : "Votre lettre à un membre du Congrès doit être publiée quelque part." 2. Le Dr Harold Koenig, médecin psychiatre et auteur et chercheur bien publié, a déclaré à propos de cet article : "Charlie - me semble tout à fait logique, et une très belle lettre en plein dans le mille ! HK 3. Stefan Schindler,  4. Dr Stephen Farra : Récemment - Université internationale émérite, Psychologie, qui a déclaré sans équivoque que "l'erreur définitiste (conduisant à un matérialisme fermé) est un poison spirituel et nous a tous blessés !"
La mort est le fruit de votre imagination: sophisme défininiste en tant que stéréotype inadapté: "la spiritualité est irréelle" - étant au-delà de toute mesure [Miller et Thompson] - Filtrage - W James - Critique approuvée Drs Koenig, Wong,, Farra,
Creators: name: Peck Jr, Charles
Publisher: name: unknown
Year: 2008
Subjects: subject: Ideology
subject: Spiritual life
subject: Logic
subject: Philosophy, French
subject: Spirituality
subject: Spirituality--Christianity
subject: Science
subject: Mannheim, Karl, 1893-1947
subject: Science--Methodology
subject: Naturalistic fallacy

description: Pourquoi un sophisme est-il important ? Bouddha dit que « nous devenons ce que nous pensons ». Hier, je parlais à un diplômé philippin (je séjourne actuellement à Gneral Santos, aux Philippines). J'ai évoqué le principal argument martérialiste tel qu'expliqué par MIller et Thompson dans un article publié sur le site Web du NIH - Pubmed - qui affirme que la spiritualité n'est pas mesurable - et n'existe donc pas. Elle a dit - "Oh oui, c'est vrai!" J'ai demandé ce qu'il en était de la compassion ? Elle a dit que la spiritualité de la compassion n'est pas mesurable. J'ai souligné que des études génétiques sur l'empathie avaient été faites et qu'une étude sur la spiritualité de la compassion avait été faite avec des résultats positifs. Ensuite, il y a l'étude sur la spiritualité des autistes réalisée par le Dr Visuri, ainsi qu'un grand nombre d'études réalisées sur la spiritualité de la musique. J'ai poursuivi en disant - si vous suivez cette ligne pour raisonner la "mort" - ce qui est bien au-delà de la mesure ou de la quantification est alors un non-sens et un produit de votre imagination. Elle était d'accord avec mon argument là-dessus.

Un extrait - Approbations et qualifications :
1. Le Dr Paul Wong : auteur, chercheur et théoricien éminent, ainsi qu'un psychologue existentiel-positif a déclaré à propos de cet essai : "Votre lettre à un membre du Congrès doit être publiée quelque part."
2. Le Dr Harold Koenig, médecin psychiatre et auteur et chercheur bien publié, a déclaré à propos de cet article : "Charlie - me semble tout à fait logique, et une très belle lettre en plein dans le mille ! HK
3. Stefan Schindler,
4. Dr Stephen Farra : Récemment - Université internationale émérite, Psychologie, qui a déclaré sans équivoque que "l'erreur définitiste (conduisant à un matérialisme fermé) est un poison spirituel et nous a tous blessés !"
Complete traumatic laceration of the superior mesenteric vein after a blunt abdominal injury in a pediatric patient
Creators: name: Lešková, Jana
name: Leško, Michal
name: Štichhauer, Radek
name: Guňka, Igor
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Hematology

description: Isolated injury to the superior mesenteric vein (SMV) caused by blunt abdominal trauma is rare but often lethal, especially in pediatric patients. Due to the low incidence of SMV injuries, there are no universal guidelines for its diagnosis and treatment. The diagnosis is made using either computed tomography (CT) or intraoperative exploration. Primary vascular repair is recommended. A 10-year-old girl was transferred to a trauma center after a high-energy motor vehicle collision. Under the diagnosis of acute abdomen with hemoperitoneum, the patient underwent urgent laparotomy, 34 min after admission to the hospital. A complete laceration of the SMV trunk was observed. Definitive vascular repair of the transected SMV was performed. An interposition graft from the internal jugular vein was used with a good postoperative course. This case report demonstrates that definitive vascular repair of the SMV reduces the risk of intestinal ischemia and should be performed in cases where ligation presents a real threat to small bowel viability. In cases of severe SMV injury, the internal jugular vein is a high-quality and easily accessible graft.
Nano-puerarin regulates tumor microenvironment and facilitates chemo- and immunotherapy in murine triple negative breast cancer model
Creators: name: Wang, M
name: Xu, H
name: Guan, K
name: Li, J
name: Li, L
name: Huang, L
name: Hu, M
name: Zhang, J
name: Liu, M
name: An, S
Publisher: name: Elsevier Ltd
Year: 2020

description: Tumor associated fibroblasts (TAFs) are key stromal cells mediating the desmoplastic reaction and being partially responsible for the drug-resistance and immunosuppressive microenvironment formation in solid tumors. Delivery of genotoxic drugs off-targetedly to kill TAFs results in production of Wnt16 which renders the neighboring tumor cells drug resistant as shown in our previous study (PMC4623876). Our current approach looks for means to deactivate, rather than kill, TAFs. Reactive oxygen species (ROS) are the central hub of multiple profibrogenic pathways and indispensable for TAFs activation. Herein, puerarin was identified to effectively downregulate ROS production in the activated myofibroblast. In this study, a novel puerarin nanoemulsion (nanoPue) was developed to improve the solubility and bioavailability of puerarin. NanoPue significantly deactivated the stromal microenvironment (e.g., ~6-fold reduction of TAFs in nanoPue treated mice compared with the PBS control, p < 0.0001) and facilitated chemotherapy effect of nano-paclitaxel in the desmoplastic triple-negative breast cancer (TNBC) model. Moreover, the removal of the physical barrier increased intra-tumoral infiltration of cytotoxic T cell by 2-fold. This activated immune microenvironment allowed nanoPue to synergize PD-L1 blockade therapy in TNBC model.
Proposal of a progressive thermalization fusion reactor able to produce nuclear fusions with a mechanical gain superior or equal to 18
Creators: name: LINDECKER Patrick
Publisher: name: Zenodo
Year: 2021
Subjects: Fusion
Reactor
Electricity production
Spatial propulsion

description: For the published article in the "Energy and Power Engineering" journal: https://doi.org/10.4236/epe.2022.141003 In the standard fusion reactors, mainly tokamaks, the plasma, in thermal equilibrium, is heated up to an energy of about 15 keV with complicated devices. At the present time, the mechanical gain obtained by these reactors is below 1. In the other hand, there are colliding beam fusion reactors, as for example the « Fusor », for which, the particles are initially injected radially. The plasma not being neutral in these reactors, the space charge limits the number of fusions to a very small number. Consequently, for this reason and for others reasons, the mechanical gain is extremely low. The proposed reactor is also a colliding beam fusion reactor using initial directed beams, but D+/T+ ions are injected in opposition, with electrons, at high speeds, so as to form a neutral beam. All these particles turn in a magnetic loop in form of figure of “0” (“racetrack”). The plasma is initially non-thermal but, as expected, rapidly becomes thermal, so all states between non-thermal and thermal exists in this reactor. The main advantage of this reactor is that this plasma after having been brought up near to the optimum conditions for fusion (around 68 keV), is then maintained in this state, thanks to low energy non-thermal ions (≤15 keV). So the energetic cost is low and the mechanical gain (Q) is elevated (≥18). There is no net plasma current inside this reactor, so no disruptive instabilities and consequently, the working is continuous. Moreover, the main plasma control by the particles injectors (I and U) is relatively simple. This reactor has been partly checked on a simulator.
Divald_Methodological_Appendix_July2020_FINAL – Supplemental material for Looking to the Past to Survive the Future: The Hungarian Minority in Slovakia
Creators: name: Divald, Susan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 160607 International Relations
subject: FOS: Political science
subject: 120505 Regional Analysis and Development
subject: FOS: Social and economic geography

description: Supplemental material, Divald_Methodological_Appendix_July2020_FINAL for Looking to the Past to Survive the Future: The Hungarian Minority in Slovakia by Susan Divald in East European Politics & Societies and Cultures
Bioinformatics internship program
Creators: name: Jigisha, Anupama
name: Francescatto, Margherita
name: Rahman, Farzana
name: Nazeefa Fatima
name: Santos, Alberto
name: Pandurang Kolekar
name: Shanmugam, Avinash Kumar
name: Venkata Satagopam
name: DeBlasio, Dan
name: Michaut, Magali
name: Guney, Emre
Publisher: name: F1000 Research Limited
Year: 2018

description: Education and training are two essential ingredients for a successful career. On one hand, universities provide students the curriculum for specializing in one’s field of study, and on the other, internships complement coursework, and provide invaluable training experience for a fruitful career. Consequently, undergraduates and graduates are encouraged to undertake an internship during the course of their degree. The opportunity to explore one’s research interests in the early-stages of their education is important for students, as it improves their skill set and gives their career a boost. In the long term, this helps to close the gap between skills and employability  among students across the globe, and balance the research capacity in the field of computational biology. However, training opportunities are often scarce for computational biology students, particularly for those who reside in less privileged regions. Aimed at helping students develop research and academic skills in computational biology, and alleviating the divide across countries, the Student Council of the International Society for Computational Biology introduced its Internship Program in 2009. The Internship Program is committed to provide access to computational biology training, especially for students from developing regions, and improving competencies in the field. The poster provides information on how the Internship Program works.
Additional file 1 of Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry
Creators: name: Heming, Michael
name: Müller-Miny, Louisa
name: Rolfes, Leoni
name: Schulte-Mecklenbeck, Andreas
name: Brix, Tobias J.
name: Varghese, Julian
name: Pawlitzki, Marc
name: Pavenstädt, Hermann
name: Kriegel, Martin A.
name: Gross, Catharina C.
name: Wiendl, Heinz
name: Meyer zu Hörste, Gerd
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Figure S1. Gating scheme. Figure S2. Comparison of blood and CSF parameters between CTD and N-CTD in relapse and remission. Figure S3. Correlation analysis between disease duration and blood and CSF parameters in CTD and N-CTD. Figure S4. Multivariable models differentiating N-CTD from CTD.