A reference panel of 64,976 haplotypes for genotype imputation
Creators: name: Dorr, Marcus
name: Traglia, Michela
name: Toniolo, Daniela
name: Chew, Emily
name: Cocca, Massimiliano
name: Wijmenga, Cisca
name: Dekker, Annelot
name: Ripatti, Samuli
name: Myers, Richard M.
name: Wood, Andrew R.
name: Schlessinger, David
name: Swaroop, Anand
name: Teumer, Alexander
name: McCarthy, Shane
name: Palotie, Aarno
name: Chen, Sai
name: Corbin, Laura J.
name: McCarroll, Steven
name: Zeggini, Eleftheria
name: Veldink, Jan
name: Sampson, Matthew G.
name: Breen, Gerome
name: Tuomilehto, Jaakko
name: Vincent, John B.
name: Gandin, Ilaria
name: Van Rheenen, Wouter
name: Das, Sayantan
name: Angius, Andrea
name: McInnis, Melvin
name: Meitinger, Thomas
name: Zhang, He
name: Kretzler, Matthias
name: Kang, Hyun Min
name: Walter, Klaudia
name: De Bakker, Paul I. W.
name: Gilly, Arthur
name: Spector, Timothy
name: Min, Josine L.
name: Gasparini, Paolo
name: Danecek, Petr
name: Melzer, David
name: Timpson, Nicholas
name: Sala, Cinzia
name: Small, Kerrin
name: Kretzschmar, Warren
name: Kwong, Alan
name: Scott, Laura J.
name: Wilson, James F.
name: Lee, James C.
name: Holmen, Oddgeir L.
name: Stambolian, Dwight
name: Marchini, Jonathan
name: Iacono, William
name: Durbin, Richard
name: Luo, Yang
name: Peters, Ulrike
name: Soranzo, Nicole
name: Schoenherr, Sebastian
name: Slagboom, P Eline
name: Campbell, Harry
name: Forer, Lukas
name: Groop, Leif
name: Mohlke, Karen L.
name: Richards, J Brent
name: Nickerson, Deborah
name: Hattersley, Andrew
name: Anderson, Carl A.
name: Tuke, Marcus
name: McGue, Matt
name: Fuchsberger, Christian
name: Pirastu, Nicola
name: Vrieze, Scott
name: Ferrucci, Luigi
name: Mahajan, Anubha
name: Harrison, Tabitha
name: Boehnke, Michael
name: Cucca, Francesco
name: Chan, Andrew
name: Van Duijn, Cornelia M.
name: Swertz, Morris A.
name: Kooperberg, Charles
name: Mezzavilla, Massimo
name: Gabriel, Stacey
name: Sidore, Carlo
name: Sharp, Kevin
name: Koskinen, Seppo
name: Delaneau, Olivier
name: Altshuler, David
name: Boomsma, Dorrett
name: Willer, Cristen
name: McCarthy, Mark I.
name: Farmaki, Aliki-Eleni
name: Van Den Berg, Leonard H.
name: Collins, Francis S.
name: Smith, George Davey
name: Dedoussis, George
name: Busonero, Fabio
name: Branham, Kari
name: Salomaa, Veikko
name: Levy, Shawn
name: Pato, Carlos
name: Volker, Uwe
name: Barrett, Jeffrey C.
name: Abecasis, Gonçalo
name: Pato, Michele
name: Nauck, Matthias
name: Hveem, Kristian
name: Gillies, Christopher E.
name: Brummett, Chad M.
name: Fraser, Ross M.
name: Frayling, Timothy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1%, a large increase in the number of SNPs tested in association studies and can help to discover and refine causal loci. We describe remote server resources that allow researchers to carry out imputation and phasing consistently and efficiently.