cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 6 of JP3, an antiangiogenic peptide, inhibits growth and metastasis of gastric cancer through TRIM25/SP1/MMP2 axis
Creators: name: Chen, Jun-Jie
name: Ren, Yan-Lin
name: Shu, Chuan-Jun
name: Zhang, Yi
name: Chen, Min-Juan
name: Xu, Jin
name: Li, Jin
name: Li, Ai-Ping
name: Chen, Dong-Yin
name: He, Jing-Dong
name: Shu, Yong-Qian
name: Zhou, Jian-Wei
Publisher: name: figshare
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional files 6: Figure S5. The mRNA level of SP1 is not affected by JP3 treatment in BGC823 and SGC7901.
EFFECT OF SPECIFIC STRENGTH TRAINING ON SELECTED PHYSIOLOGICAL PARAMETERS AMONG COLLEGE MEN NETBALL PLAYERS
Creators: name: Naveen Kumar Daram* & Dr. S. Umanath**
Publisher: name: Zenodo
Year: 2022

description: The purpose of the study was designed to examine the effect of specific strength training on resting pulse rate and breath holding time among college men Netball players. For the purpose of the study, thirty college men Netball players from the affiliated colleges under Krishna University, Krishna District, Andhra Pradesh State, India were selected as subjects.  They were divided into two equal groups.  each group consisted of fifteen subjects. Group I underwent specific strength training for three days per week for twelve weeks.  Group II acted as control who did not undergo any special training programme apart from their regular physical education programme. The following variables, namely resting pulse rate and breath holding time were selected as criterion variables.  All the subjects of two groups were tested on selected dependent variables namely resting pulse rate and breath holding time by using radial pulse and holding the breath for time at prior to and immediately after the training programme. The analysis of covariance was used to analyze the significant difference, if any among the groups. The .05 level of confidence was fixed as the level of significance to test the ‘F’ ratio obtained by the analysis of covariance, which was considered appropriate. The results of the study showed that there was a significant difference between specific strength training group and control group on resting pulse rate and breath holding time. And also it was found that there was a significant improvement on selected criterion variables such as resting pulse rate and breath holding time due to specific strength training.
A DFT Study of Electronic Structures and Relative Stabilities of Isomeric n,m-Diazaphenanthrenes
Creators: name: Aliveisi, Rahman
name: Avat (Arman) Taherpour
name: Yavari, Issa
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Inorganic Chemistry
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: In this study, the structural properties, energetic data, and classification of the chemical properties of n,m-diazaphenanthrine derivatives were studied by a density functional theory (DFT) method. The important and proper indices were applied in this investigation. The structures, electronic properties, and chemical reactivities of 25 isomeric n,m-diazaphenanthrenes were studied by a B3LYP/6–31+G(d) method/basis set. All the optimized geometries of these isomers kept good planarity. The structural properties such as bond lengths and dipole moments of these isomers were calculated. The energies of frontier orbitals (HOMO and LUMO) are used to determine several chemical reactivity parameters as a measure of their relative stabilities. These include total energy (E), ionization potential (I), electron affinity (A), chemical hardness (η), chemical softness (S), electronic chemical potentials (μ), and electrophilicity (ω). Based on these calculations, the heats of formation (ΔH°f) for all the n,m-diazaphenanthrine derivatives are predicted. Benzo[h]quinazoline (P13) and benzo[f]cinnoline (P34) are calculated to be the most stable and the least stable isomers, respectively. 1,10-Phenanthroline (P110) possesses the minimum electrophilicity, while benzo[c]cinnoline (P56) is calculated to have the highest electrophilicity among the isomeric structures. The largest and smallest dipole moments are calculated for benzo[f]phthalazine (P23) and 3,8-phenanthroline (P38), respectively. Linear relationships between the calculated ELUMO (in eV) values and electrophilicity (ω) of the isomeric n,m-diazaphenanthrenes were observed.
title: ADCO, Sixième cartulaire de Saint-Étienne de Dijon (1662), Cart. 30 (G 133), 441 folios, f. 811
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 811, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Sixième cartulaire de Saint-Étienne de Dijon (1662), Archives départementales de la Côte-d'Or, Cart. 30 (G 133), 441 folios, f. 811, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Bevölkerungsorientierte Ansätze der Gesundheitsförderung
Creators: name: Iff, Tanja
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2015

description: Unser Lebensstil und unsere Lebensbedingungen haben sich in den letzten Jahren verändert. Dadurch sind nichtübertragbare Krankheiten wie Krebs oder Diabetes angestiegen. Diese werden durch Risikofaktoren wie Alkoholmissbrauch oder Rauchen begünstigt, welche von individuellen Lebensstilen und gesellschaftlichen Rahmenbedingungen abhängen (BAG, 2015). Das Bundesamt für Gesundheit (BAG) erarbeitet eine Strategie zur Prävention nichtübertragbarer Krankheiten, um den Risikofaktoren entgegenzuwirken. Zur Erreichung der Bevölkerung stehen folgende drei Ansätze zur Auswahl: Setting-, Zielgruppen- und Lebensphasenansatz. Ziel dieser Studie war es, durch Literaturrecherche und Experteninterviews positive und negative Aspekte dieser Ansätze wie auch Beispiele aus der Praxis aufzuzeigen, um den bevorzugten Ansatz zu identifizieren. Es zeigte sich, dass alle Ansätze bei der Erarbeitung einer Strategie miteinzubeziehen sind, um den grösstmöglichen Effekt bei der Bevölkerung zu erreichen.
Advancing COVID-19 Diagnosis with Privacy-Preserving Collaboration in Artificial Intelligence.
Creators: name: Bai, Xiang
name: Wang, Hanchen
name: Ma, Liya
name: Xu, Yongchao
name: Gan, Jiefeng
name: Fan, Ziwei
name: Yang, Fan
name: Ma, Ke
name: Yang, Jiehua
name: Bai, Song
name: Shu, Chang
name: Zou, Xinyu
name: Huang, Renhao
name: Zhang, Changzheng
name: Liu, Xiaowu
name: Tu, Dandan
name: Xu, Chuou
name: Zhang, Wenqing
name: Wang, Xi
name: Chen, Anguo
name: Zeng, Yu
name: Yang, Dehua
name: Wang, Ming-Wei
name: Holalkere, Nagaraj
name: Halin, Neil J
name: Kamel, Ihab R
name: Wu, Jia
name: Peng, Xuehua
name: Wang, Xiang
name: Shao, Jianbo
name: Mongkolwat, Pattanasak
name: Zhang, Jianjun
name: Liu, Weiyang
name: Roberts, Michael
name: Teng, Zhongzhao
name: Beer, Lucian
name: Sanchez, Lorena Escudero
name: Sala, Evis
name: Rubin, Daniel
name: Weller, Adrian
name: Lasenby, Joan
name: Zheng, Chuangsheng
name: Wang, Jianming
name: Li, Zhen
name: Schönlieb, Carola-Bibiane
name: Xia, Tian
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Article
/4000/4008
/692/700
/639/705/1042
/631/326/596/4130
article

description: Artificial intelligence (AI) provides a promising substitution for streamlining COVID-19 diagnoses. However, concerns surrounding security and trustworthiness impede the collection of large-scale representative medical data, posing a considerable challenge for training a well-generalised model in clinical practices. To address this, we launch the Unified CT-COVID AI Diagnostic Initiative (UCADI), where the AI model can be distributedly trained and independently executed at each host institution under a federated learning framework (FL) without data sharing. Here we show that our FL model outperformed all the local models by a large yield (test sensitivity /specificity in China: 0.973/0.951, in the UK: 0.730/0.942), achieving comparable performance with a panel of professional radiologists. We further evaluated the model on the hold-out (collected from another two hospitals leaving out the FL) and heterogeneous (acquired with contrast materials) data, provided visual explanations for decisions made by the model, and analysed the trade-offs between the model performance and the communication costs in the federated training process. Our study is based on 9,573 chest computed tomography scans (CTs) from 3,336 patients collected from 23 hospitals located in China and the UK. Collectively, our work advanced the prospects of utilising federated learning for privacy-preserving AI in digital health.
FEMSPIN Report: Spin-Offs and Start-Ups of Female Academics at Swiss Universities: Activities and Support
Creators: name: Liebig, Brigitte
name: Soltermann, Alain
Publisher: name: Hochschule für Angewandte Psychologie FHNW
Year: 2023
Subjects: subject: diversity
subject: innovation
subject: entrepreneurship
subject: femspin
subject: 300 - Sozialwissenschaften

description: This report aims to encourage reflection, exchange, and knowledge building on female academic entrepreneurship in Switzerland. It presents new data on spin-off and start-up activities by female academics at Swiss universities and research institutes. The survey highlights that female academics are still rarely involved in the commercialization of knowledge from R&D in Switzerland. More than that, most of Swiss universities and research institutes offer support for academic entrepreneurship in general, but few specifically target their support at female academics. The authors make clear, that activities are needed to support spin-off and start-up creation in all fields of research with a particular focus on women. A close collaboration between gender equality, knowledge transfer, and innovation is essential to close the existing gender gap in academic entrepreneurship.
Laboratory Reports on Radiocarbon Age Determination. Bentinck Island, South Wellesleys, Gulf of Carpentaria, QLD, AUS (2008-2011)
Creators: name: Hogg, Alan
name: Ulm, Sean G. F.
Publisher: name: Zenodo
Year: 2008
Subjects: Sahul
Archaeology
Radiocarbon
SahulArch
OCTOPUS database
Lab report
Bentinck Island

description: Original Radiocarbon Dating Lab reports for samples ARCH0747C14001_Wk-23663, ARCH0748C14001_Wk-23664, ARCH0749C14001_Wk-23665, ARCH0750C14001_Wk-23661, ARCH0750C14002_Wk-23662, Wk-28560, Wk-28561, Wk-32135, Wk-32136 where ARCHxxxC14xxx is the OCTOPUS database observation ID and Wk_xxxxx is the original lab ID Sample batch originates from Bentinck Island, South Wellesleys, Gulf of Carpentaria, QLD, AUS The University of Waikato, Radiocarbon Dating Laboratory
title: ADCO, Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Cart. 23 (G 127), 310 folios, f. 00044
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2011
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00044, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Troisième cartulaire de Saint-Étienne de Dijon (XVIe), Archives départementales de la Côte-d'Or, Cart. 23 (G 127), 310 folios, f. 00044, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Enhancement of Biochemical and Nutritional Contents of Some Cultivated Seaweeds Under Laboratory Conditions
Creators: name: Ismail, Mona M.
name: El-Sheekh, Mostafa
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: Science Policy

description: Six species of macroalgae belonging to the Chlorophyta, Phaeophyta, and Rhodophyta divisions were cultivated in a closed system with Guillard's f/2, Walne's, Provasoli Enriched Seawater (PES) medium, and seawater (control) for 6 weeks. The growth rate and parameters of the tested seaweeds showed that all used media enhanced the growth rate and chemical content as compared with other seaweeds cultivated in seawater without addition of any nutrients. There are significant differences in the effect of the used media on the seaweed composition at p = .01; PES is more effective than the f/2 and Walne's media. The results indicate that the cultivation technique of some macroalgae was an efficient tool for increasing the seaweeds' biomass and increasing their chemical compounds, calories, and energy under laboratory conditions.
Absenzenmanagement bei der Digitec Galaxus AG: Analyse der Absenzen und der Selbstgefährdung als Basis für eine Weiterentwicklung des Absenzenmanagements
Creators: name: Rüesch, Stefanie
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2018
Subjects: Absenzen
Absenzenmanagement
Arbeitsbelastungen
Arbeitsressourcen
Commitment
Gesundheitsbeeinträchtigungen
Selbstgefährdung
Job Demands
Job Resources

description: Die vorliegende Studie untersuchte den Zusammenhang zwischen Arbeitsressourcen, Arbeitsbelastungen, krankheitsbedingten Absenzen und Selbstgefährdung bei den Mitarbeitenden der Digitec Galaxus AG (Abteilungen Engineering & Supply Chain Management) um so deren Absenzenmanagement weiterzuentwickeln. Dabei sollten Mediationszusammenhänge aufgezeigt und durch die Konstrukte Gesundheitsbeeinträchtigungen und Commitment aufgedeckt werden. Den theoretischen Hintergrund bildete das Job Demands Ressources-Modell, welches um das Konstrukt der Selbstgefährdung erweitert wurde. Das methodische Vorgehen gliederte sich in teilstrukturierte Leitfadeninterviews (N= 7) als Basis für die darauffolgende Online-Befragung (N= 143). Die Ergebnisse der Regressionsanalysen mit Mediatoren zeigten auf, dass Arbeitsbelastungen theoriekonform mit Absenzen zusammenhängen. Der Hauptprädiktor für Selbstgefährdung waren die Arbeitsressourcen. Die Abteilungen Engineering und Supply Chain Management unterschieden sich in der überwiegenden Mehrheit der Merkmale. Die Engineers verfügten über mehr Arbeitsressourcen, Commitment und weniger Selbstgefährdung und waren seltener krankheitsbedingt abwesend.
Preparing to lead effectively through emerging challenges
Creators: name: Hering, Janet G.
name: Maurice, Patricia A.
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Gender equality
subject: leadership
subject: diversity

description: Leadership is always dynamic, never static.  Here are some ideas for how a leader can prepare for, identify, and respond effectively to emerging challenges and, ideally, turn them into opportunities.  This is a copy of a blog posted on the Epistimi website at: https://www.epistimi.org/blog/preparing-to-lead-effectively-through-emerging-challenges
LanB1 Cooperates With Kon-Tiki During Embryonic Muscle Migration in Drosophila.
Creators: name: Pérez-Moreno, Juan José
name: Santa-Cruz Mateos, Carmen
name: Martín-Bermudo, María Dolores
name: Estrada, Beatriz
Publisher: name: Apollo - University of Cambridge Repository
Year: 2021
Subjects: Drosophila
Migration
Laminin
myogenesis
adhesion
Ng2
Kon-tiki
Myotendinous Junction (Mtj)

description: Muscle development is a multistep process that involves cell specification, myoblast fusion, myotube migration, and attachment to the tendons. In spite of great efforts trying to understand the basis of these events, little is known about the molecular mechanisms underlying myotube migration. Knowledge of the few molecular cues that guide this migration comes mainly from studies in Drosophila. The migratory process of Drosophila embryonic muscles involves a first phase of migration, where muscle progenitors migrate relative to each other, and a second phase, where myotubes migrate searching for their future attachment sites. During this phase, myotubes form extensive filopodia at their ends oriented preferentially toward their attachment sites. This myotube migration and the subsequent muscle attachment establishment are regulated by cell adhesion receptors, such as the conserved proteoglycan Kon-tiki/Perdido. Laminins have been shown to regulate the migratory behavior of many cell populations, but their role in myotube migration remains largely unexplored. Here, we show that laminins, previously implicated in muscle attachment, are indeed required for muscle migration to tendon cells. Furthermore, we find that laminins genetically interact with kon-tiki/perdido to control both myotube migration and attachment. All together, our results uncover a new role for the interaction between laminins and Kon-tiki/Perdido during Drosophila myogenesis. The identification of new players and molecular interactions underlying myotube migration broadens our understanding of muscle development and disease.
Einfluss von Eingabegeräten auf die VR-Krankheit
Creators: name: Travaglini, Alessio
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019

description: Noch immer stellt die Simulatorkrankheit im VR-Bereich eine ungelöste Problematik dar. Besonders bei Fahr- oder Flugsimulatoren führt eine Wahrnehmungsdiskrepanz oft zu Übelkeit und Schwindel. Die Studie überprüfte die Annahme, dass ein leichter Stimulus des Gleichgewichtsinns mit Hilfe eines VRGos, welcher im Gegensatz zu herkömmlichen Eingabegeräten mit Neigung als Steuerung agiert, diese Diskrepanz verhindert oder vermindert. Es wurden sowohl bei der Zeit bis zur Übelkeit als auch bei der Stärke von Symptomen der Simulatorkrankheit eine Tendenz festgestellt, welche diese These unterstützen, welche allerdings die nötige statistische Signifikanz nicht erreicht.
GROUND MOTION PARAMETRS FOR THE 2011GREAT JAPAN TOHOKU EARTHQUAKE
Creators: name: Bhargavi Podili
name: STG Raghukanth
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Evolutionary Biology
subject: Ecology
subject: Cancer
subject: Plant Biology

description: The 2011 great Japan Tohoku earthquake (Mw 9.0) is not only the most devastating but also, one of the best recorded earthquakes in the history of seismology. Strong motion characteristics of this earthquake are studied using well established ground motion parameters. A total of 20 parameters are extracted from the data. The behaviour of these parameters with fault distance and average shear wave velocity is examined and their values for stations MYG004 and TCGH16 are tabulated. Further, an attenuation relationship is developed using the 1172 surface level strong motion records. Also, Principal Component Analysis is used in classification of the derived GMPs, which is further used to rate the damage potential of ground motion records.
Water-soluble optical sensors: keys to detect aluminium in biological environment
Creators: name: Unniram, Ajmal
name: Kavyashree, P.
name: Silswal, Akshay
name: Koner, Apurba Lal
Publisher: name: Royal Society of Chemistry
Year: 2022
Subjects: subject: 600 - Technik, Medizin, angewandte Wissenschaften

description: Metal ion plays a critical role from enzyme catalysis to cellular health and functions. The concentration of metal ions in a living system is highly regulated. Among the biologically relevant metal ions, the role and toxicity of aluminium in specific biological functions have been getting significant attention in recent years. The interaction of aluminium and the living system is unavoidable due to its high earth crust abundance, and the long-term exposure to aluminium can be fatal for life. The adverse Al3+ toxicity effects in humans result in various diseases ranging from cancers to neurogenetic disorders. Several Al3+ ions sensors have been developed over the past decades using the optical responses of synthesized molecules. However, only limited numbers of water-soluble optical sensors have been reported so far. In this review, we have confined our discussion to water-soluble Al3+ ions detection using optical methods and their utility for live-cell imaging and real-life application.
COMPARISON OF SELECTED PHYSICAL FITNESS COMPONENTS BETWEEN RURAL SCHOOL KABADDI AND KHO-KHO PLAYERS
Creators: name: Rangana Gowda* & Dr. M. Velmurugan**
Publisher: name: Zenodo
Year: 2022

description: The purpose of the study was to compare the muscular endurance and cardio respiratory endurance between rural school kabaddi and kho-kho players.  To achieve this purpose of the study, sixty players studying in the rural schools in Karnataka state, India were selected as subjects at random.  Among them, thirty kabaddi players and thirty kho-kho players were selected. Among the physical fitness components, the following variables namely muscular endurance and cardio respiratory endurance were selected as criterion variables.  All the subjects of two groups were tested on selected dependent variables by using bend knee sit ups and cooper’s 12 min run / walk test. The independent ‘t’ ratio was used to analyze the significant difference, if any between groups.  The .05 level of confidence was fixed as the level of significance to test the ‘t’ ratio obtained, which was considered as an appropriate. The results of the study showed that there was a significant difference between kabaddi players and kho-kho players on muscular endurance and cardio respiratory endurance.
A non-essentialist model of culture
Creators: name: Nathan, Ganesh
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2015
Subjects: Non-essentialist model of culture
Cross Cultural Management
Multinational/Multicultural Organizations

description: Mainly based on the article published: Nathan, G. 2015. A non‐essentialist model of culture: Implications of identity, agency and structure within multinational/multicultural organizations, International Journal of Cross Cultural Management, Vol. 15(1): 101‐124
title: Transcriptions du Y//3 - Livre rouge , page #068
Creators: name: Brochard, Pierre
name: Claustre, Julie
name: Regazzi, Hugo
name: Claustre, Julie
name: Brochard, Pierre
name: Regazzi, Hugo
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2022
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Châtelet de Paris
subject: http://www.idref.fr/032506511/id
subject: Laboratoire de médiévistique occidentale de Paris

description: Transcriptions de certaines pages du Y//3 - Livre Rouge, Châtelet de Paris, Y//1-Y//6/6. Livres de couleur (1223-1604)
Les images liées sont indiquées par le champ Source.

Les transcriptions sont dans deux formats : Txt et PageXml.

Liste des abréviations

App(b)eillees = appareillées
Bouch'r = boucher
Com'e = comme
Laut' = l'autre
Daut' = d'autre
Par' = Paris
Com'andem's = commandemens
Cestass' = c'est assavoir
Envir' = environ
App(b)tient = appartient
Ass' = assavoir
Ch'un = chascun
Oucas = ou cas
Enioint = enjoint
T'spas = trespas
Entiere = entière
Aleurs = à leurs

Les apostrophes représentent les tildes et '(b)' signifie que le jambage de la lettre précédente est barré.
description: Source: https://www.siv.archives-nationales.culture.gouv.fr/siv/media/FRAN_IR_056373/c-2xp1c58jd-1w19uv1g8sus6/FRAN_0053_01068_L
description: Source: https://www.nakala.fr/10.34847/nkl.8e62ja00
description: Relation: https://lamop.hypotheses.org/
description: Bibliographic citation: Hugo Regazzi, Pierre Brochard, Julie Claustre - Transcriptions du Y//3 - Livre Rouge du Châtelet de Paris, page #01068
description: Transcriptions du Y//3 - Livre Rouge page #068 - Format Text
description: Transcriptions du Y//3 - Livre Rouge page #068 - Format PageXML
pH-sensitive pHLIP® coated niosomes
Creators: name: Pereira, Mohan C.
name: Pianella, Monica
name: Wei, Da
name: Moshnikova, Anna
name: Marianecci, Carlotta
name: Carafa, Maria
name: Andreev, Oleg A.
name: Reshetnyak, Yana K.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Nanomedicine is becoming very popular over conventional methods due to the ability to tune physico-chemical properties of nano vectors, which are used for encapsulation of therapeutic and diagnostic agents. However, the success of nanomedicine primarily relies on how specifically and efficiently nanocarriers can target pathological sites to minimize undesirable side effects and enhance therapeutic efficacy. Here, we introduce a novel class of targeted nano drug delivery system, which can be used as an effective nano-theranostic for cancer. We formulated pH-sensitive niosomes (80–90 nm in diameter) using nonionic surfactants Span20 (43–45 mol%), cholesterol (50 mol%) and 5 mol% of pH (Low) insertion peptide (pHLIP) conjugated with DSPE lipids (DSPE-pHLIP) or hydrophobic fluorescent dye, pyrene, (Pyr-pHLIP). In coating of niosomes, pHLIP was used as an acidity sensitive targeting moiety. We have demonstrated that pHLIP coated niosomes sense the extracellular acidity of cancerous cells. Intravenous injection of fluorescently labeled (R18) pHLIP-coated niosomes into mice bearing tumors showed significant accumulation in tumors with minimal targeting of kidney, liver and muscles. Tumor-targeting niosomes coated with pHLIP exhibited 2–3 times higher tumor uptake compared to the non-targeted niosomes coated with PEG polymer. Long circulation time and uniform bio-distribution throughout the entire tumor make pHLIP-coated niosomes to be an attractive novel delivery system.
NeuroCharter, a software to discover the effects and contributions between interrelated features through artificial neural networks.
Creators: name: Elnesr, Mohammad
Publisher: name: figshare
Year: 2017
Subjects: subject: 80108 Neural, Evolutionary and Fuzzy Computation
subject: FOS: Computer and information sciences

description: NeuroCharter is an open-source software that helps in prediction problems in scientific research through artificial neural networks. The program is designed mainly for researchers who focus on details of the network’s parameters, in addition to easy reuse of the trained network. The program outputs almost all the necessary graphs regarding the network and features contributions and relative outputs for bot numeric and categorical features. The program was implemented in Python 2.7.11 and is open sourced for reuse and future development. The program consists of four main classes, one for the neural networks calculation, one for data manipulation, one for plotting the neural network, and the main class that manages and links the other classes.
Darwin's small and medium ground finches might have taste preferences, but not for human foods.
Creators: name: Lever, D
name: Rush, LV
name: Thorogood, R
name: Gotanda, Kiyoko
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Foraging
urbanization
Galapagos
Geospiza Fortis
Human Influences
Geospiza Fuliginosis

description: Urbanization is rapidly changing ecological niches. On the inhabited Galapagos Islands, Darwin's finches consume human-introduced foods preferentially; however, it remains unclear why. Here, we presented pastry with flavour profiles typical of human foods (oily, salty and sweet) to small ground finches (Geospiza fuliginosa) and medium ground finches (Geospiza fortis) to test if latent taste preferences might drive the selection of human foods. If human food flavours were consumed more than a neutral or bitter control only at sites with human foods, then we predicted tastes were acquired after urbanization; however, if no site differences were found then this would indicate latent taste preferences. Contrary to both predictions, we found little evidence that human food flavours were preferred compared with control flavours at any site. Instead, finches showed a weak aversion to oily foods, but only at remote (no human foods present) sites. This was further supported by behavioural responses, with beak-wiping occurring more often at remote sites after finches tasted flavours associated with human foods. Our results suggest, therefore, that while Darwin's finches regularly exposed to human foods might have acquired a tolerance to human food flavours, latent taste preferences are unlikely to have played a major role in their dietary response to increased urbanization.
Evaluation of tumour surveillance protocols and outcomes in von Hippel-Lindau disease in a national health service.
Creators: name: Maher, Eamonn
name: Adlard, Julian
name: Barwell, Julian
name: Brady, Angela F
name: Brennan, Paul
name: Cook, Jackie
name: Crawford, Gillian S
name: Dabir, Tabib
name: Davidson, Rosemarie
name: Dyer, Rebecca
name: Harrison, Rachel
name: Forde, Claire
name: Halliday, Dorothy
name: Hanson, Helen
name: Hay, Eleanor
name: Higgs, Jenny
name: Jones, Mari
name: Lalloo, Fiona
name: Miedzybrodzka, Zosia
name: Ong, Kai Ren
name: Pelz, Frauke
name: Ruddy, Deborah
name: Snape, Katie
name: Whitworth, James
name: Sandford, Richard N
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022

description: BACKGROUND: Von Hippel-Lindau (VHL) disease is an inherited tumour predisposition syndrome and a paradigm for the importance of early diagnosis and surveillance. However, there is limited information on the "real world" management of VHL disease. METHODS: A national audit of VHL disease in the United Kingdom. RESULTS: VHL disease was managed mostly via specialist clinics coordinated through regional clinical genetics services (but frequently involving additional specialties). Over the study period, 19 genetic centres saw 842 individuals (393 males, 449 females) with a clinical and/or molecular diagnosis of VHL disease and 74 individuals (35 male, 39 female) with a prior risk of 50% (affected parent). All centres offered retinal, central nervous system and abdominal surveillance to affected individuals and at-risk relatives though surveillance details differed between centres (but complied with international recommendations). Renal lesions detected on the first surveillance scan were, on average, larger than those detected during subsequent scans and the larger the diameter at detection the greater the likelihood of early intervention. CONCLUSIONS: In a state-funded health care system individuals with a rare inherited cancer predisposition syndrome are generally able to access appropriate surveillance and patient management is improved compared to historical data. The "real world" data from this study will inform the future development of VHL management protocols.
Defining the Protease and Protease Inhibitor (P/PI) Proteomes of Healthy and Diseased Human Skin by Modified Systematic Review
Creators: name: Stewart-McGuinness, Callum
name: Platt, Christopher I
name: Ozols, Matiss
name: Goh, Brian
name: Griffiths, Tamara W
name: Sherratt, Michael J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: proteome
protease
protease inhibitor
skin
human

description: Proteases and protease inhibitors (P/PIs) are involved in many biological processes in human skin, yet often only specific families or related groups of P/PIs are investigated. Proteomics approaches, such as mass spectrometry, can define proteome signatures (including P/PIs) in tissues; however, they struggle to detect low-abundance proteins. To overcome these issues, we aimed to produce a comprehensive proteome of all P/PIs present in normal and diseased human skin, in vivo, by carrying out a modified systematic review using a list of P/PIs from MEROPS and combining this with key search terms in Web of Science. Resulting articles were manually reviewed against inclusion/exclusion criteria and a dataset constructed. This study identified 111 proteases and 77 protease inhibitors in human skin, comprising the serine, metallo-, cysteine and aspartic acid catalytic families of proteases. P/PIs showing no evidence of catalytic activity or protease inhibition, were designated non-peptidase homologs (NPH), and no reported protease inhibitory activity (NRPIA), respectively. MMP9 and TIMP1 were the most frequently published P/PIs and were reported in normal skin and most skin disease groups. Normal skin and diseased skin showed significant overlap with respect to P/PI profile; however, MMP23 was identified in several skin disease groups, but was absent in normal skin. The catalytic profile of P/PIs in wounds, scars and solar elastosis was distinct from normal skin, suggesting that a different group of P/PIs is responsible for disease progression. In conclusion, this study uses a novel approach to provide a comprehensive inventory of P/PIs in normal and diseased human skin reported in our database. The database may be used to determine either which P/PIs are present in specific diseases or which diseases individual P/PIs may influence.
Бернар Белідор
Creators: name: Miroshnychenko, Marina
Publisher: name: figshare
Year: 2017
Subjects: subject: 91503 Engineering Practice
subject: FOS: Other engineering and technologies
subject: 91004 Machining
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: Mechanical Engineering
subject: FOS: Mechanical engineering

description: he history of hydraulics and the biography of the outstanding engineer and inventor Bernard Belidor
Affect and Atmosphere in Controlled Responsive Environments
Creators: name: Simon, Andreas
name: Torpus, Jan-Lewe
name: Heibach, Christiane
name: Navarro, José Javier
Publisher: name: Springer
Year: 2016
Subjects: subject: Ubicomp
subject: Biofeedback
subject: Atmosphere
subject: Environment
subject: Affection
subject: Sensemaking
subject: 700 - Künste und Unterhaltung

description: We explore the atmospheric potential and the affective connection between humans and their instrumented, responsive environments and develop corresponding artistic design strategies, evaluating ubicomp environments from a critical perspective, beyond pure application and usefulness. We have designed an abstract, cocoon-like, responsively mediated space and conducted a series of experiments with a total of 17 participants. Results show that participants experience affection, a coupling between themselves and the designed environment, and show strong cognitive engagement to understand and structure the environment through patterns of situation awareness and sensemaking.
Activation mechanism of the class D fungal GPCR dimer Ste2.
Creators: name: Velazhahan, Vaithish
name: Ma, Ning
name: Vaidehi, Nagarajan
name: Tate, Christopher G
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Article
/631/45/612/194
/631/45/535/1258/1259
/101/28
/82/80
/82/83
/82/29
article

description: The fungal class D1 G-protein-coupled receptor (GPCR) Ste2 has a different arrangement of transmembrane helices compared with mammalian GPCRs and a distinct mode of coupling to the heterotrimeric G protein Gpa1-Ste2-Ste181. In addition, Ste2 lacks conserved sequence motifs such as DRY, PIF and NPXXY, which are associated with the activation of class A GPCRs2. This suggested that the activation mechanism of Ste2 may also differ. Here we determined structures of Saccharomyces cerevisiae Ste2 in the absence of G protein in two different conformations bound to the native agonist α-factor, bound to an antagonist and without ligand. These structures revealed that Ste2 is indeed activated differently from other GPCRs. In the inactive state, the cytoplasmic end of transmembrane helix H7 is unstructured and packs between helices H1-H6, blocking the G protein coupling site. Agonist binding results in the outward movement of the extracellular ends of H6 and H7 by 6 Å. On the intracellular surface, the G protein coupling site is formed by a 20 Å outward movement of the unstructured region in H7 that unblocks the site, and a 12 Å inward movement of H6. This is a distinct mechanism in GPCRs, in which the movement of H6 and H7 upon agonist binding facilitates G protein coupling.
Supplementary Material for: Frontal Cortex Myo-Inositol Is Associated with Sleep and Depression in Adolescents: A Proton Magnetic Resonance Spectroscopy Study
Creators: name: Urrila, A.S.
name: Hakkarainen, A.
name: Castaneda, A.
name: Paunio, T.
name: Marttunen, M.
name: Lundbom, N.
Publisher: name: Karger Publishers
Year: 2017
Subjects: Medicine

description: Aim: This study used proton magnetic resonance spectroscopy (1H MRS) to evaluate the neurochemistry of the frontal cortex in adolescents with symptoms of sleep and depression. Methods: Nineteen non-medicated adolescent boys (mean age 16.0 years; 9 clinical cases with depression/sleep symptoms and 10 healthy controls) underwent 1H MRS at 3 T. MR spectra were acquired from the anterior cingulate cortex (ACC), the dorsolateral prefrontal cortex, and frontal white matter. Concentrations of N-acetyl aspartate, total creatine, choline-containing compounds, total glutamine plus glutamate, and myo-inositol (mI) were compared in the 2 subgroups, and correlated with sleep and clinical measures in the total sample. Sleep was assessed with self-report questionnaires and ambulatory polysomnography recordings. Results: Concentrations of mI were lower in both frontal cortical regions among the depressed adolescents than in controls. No statistically significant differences in other metabolite concentrations were observed between the subgroups. Frontal cortex mI concentrations correlated negatively with depression severity, subjective daytime sleepiness, insomnia symptoms, and the level of anxiety, and correlated positively with total sleep time and overall psychosocial functioning. The correlations between mI in the ACC and total sleep time as well as daytime sleepiness remained statistically significant when depression severity was controlled in the analyses. Conclusion: Lower frontal cortex mI may indicate a disturbed second messenger system. Frontal cortical mI may thus be linked to the pathophysiology of depression and concomitant sleep symptoms among maturing adolescents. Short sleep and daytime sleepiness may be associated with frontal cortex mI independently from depression.
title: The Search for Anticarcinogenic Organoselenium Compounds from Natural Sources
Creators: name: Block, Eric
name: Bird, Susan
name: Tyson, Julian
name: Uden, Peter C
name: Zhang, Xing
name: Denoyer, Eric R.
Publisher: name: University of Massachusetts Amherst
Year: 1998
Subjects: subject: Selenoamino acids
subject: ICP-MS
subject: GC-AED
subject: garlic (AJ/ium sativum )
subject: yeast
subject: Chemistry

description: Consumption of Se-enriched plants or yeast-based nutritional supplements is reported to reduce the risk of cancer. Separation and identification of natural organoselenium compounds in these plants is essential to understand the basis for their biological activity. Earlier work suggests that plants convert inorganic selenium in the soil or growth medium into organoselenium compounds, such as selenoamino acids, following a route similar to the sulfur assimilatory pathway. To separate and detect selenoamino acids in plant extracts, we employ ion pair LC with an inductively coupled plasma mass spectrometer (ICP-MS) detector and capillary GC with an atomic emission detector (AED), for underivatized and derivatized compounds, respectively. Volatile selenium compounds, such as those found in human garlic breath, have been analyzed using GCAED. Results involving Se-enriched garlic and yeast-based nutritional supplements are presented.
Three Growth Spurts in Global Physical Activity Policies between 2000 and 2019: A Policy Document Analysis
Creators: name: Muzenda, Trish
name: Shung-King, Maylene
name: Lambert, Estelle Victoria
name: Brugulat Panés, Anna
name: Weimann, Amy
name: McCreedy, Nicole
name: Tatah, Lambed
name: Mapa-Tassou, Clarisse
name: Govia, Ishtar
name: Were, Vincent
name: Oni, Tolu
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: physical activity
policy
intersectoral action
noncommunicable disease(s)

description: Non-communicable diseases (NCDs) contribute significantly to global mortality and are of particular concern in growing urban populations of low- and-middle income countries (LMICs). Physical inactivity is a key NCD determinant and requires urgent addressing. Laudable global and regional efforts to promote physical activity are being made, but the links between physical activity (PA), NCD reduction, and integrated intersectoral approaches to reducing obesogenic environments are not consistently made. This study applied a document analysis approach to global PA and NCD policies to better understand the current global policy environment and how this may facilitate integrated PA promotion. A total of 34 global policies related to PA, from different sectors, were analyzed. PA policy in mitigation of NCDs has evolved exponentially, with a progression towards addressing structural determinants alongside individual behavior change. The global PA agenda is primarily driven by the World Health Organization. Intersectoral collaboration is importantly regarded, but the contributions of other sectors, outside of health, education, transport, and urban planning, are less clear. Improving PA among key sub-populations—women, girls, and adolescents—requires greater policy consideration. It is imperative for PA-relevant sectors at all levels to recognize the links with NCDs and work towards integrated policy and practice in mitigation of the rising NCD pandemic.
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Cart. 193 (11 H 78), f. 0248r
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0248r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome IX, Archives départementales de la Côte-d'Or, Cart. 193 (11 H 78), f. 0248r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Ostwald ripening of gas bubbles in porous media: Impact of pore geometry and spatial bubble distribution
Creators: name: Singh, Deepak
name: Friis, Helmer André
name: Jettestuen, Espen
name: Helland, Johan Olav
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 401907
subject: Petroleum and reservoir engineering
classificationCode: 410101
subject: Carbon sequestration science

description: This dataset pertains to simulations on Ostwald ripening phenomenon using Ghost bubble and bubble-to-bubble method with a level set approach. The data corresponds to a submitted paper and the sheet names reflect the section number of the result and discussion section. For further details of the model and simulations, the doi of the published article will be provided.