cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Biodiversity Genomics Europe | Pollinator Communities - Malaise trap sampling
Creators: name: Najera Cortazar, Laura
name: Ferreira, Sonia
name: Beja, Pedro
Publisher: name: WorkflowHub
Year: 2024

description: Within the Biodiversity Genomics Europe project, the "Pollinator Communities" case study was designed to evaluate pollinator diversity in urban gardens in comparison with agricultural fields, to understand the role of urban habitats for pollinator conservation. This SOP describes the sampling design and Malaise trap fieldwork to retrieve pollinator bulk samples for metabarcoding analysis. This case study involved paired sampling, choosing one large garden and one agricultural field with no more than 20 Km distance between them, to perform a parallel sampling using a Malaise trap per site. Tubes with specimens of both traps were collected on the same day of the week, during five weeks. The "Biodiversity Genomics Europe | Pollinator Communities – Malaise trap sampling” intends establishing a baseline of pollinator (and other arthropods) monitoring along habitats that function as surrogates for ecosystem services.
Parametriocnemus undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Parametriocnemus
Parametriocnemus undetermined

description: Parametriocnemus sp.
Notes
Morpho identification. New record for Lithuania.
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
title: Plan der Stadt Marburg mit ihrer Umgebung
Creators: name: Gerling, Christian Ludwig
name: Gironcourt, Adolphe de
Publisher: name: Philipps-Universität Marburg
Year: 2022
Subjects: Stadtplan
Marburg
Altkarte
Geography & travel Germany
Landeskunde Deutschlands

description: Elektronische Reproduktion von: Plan der Stadt Marburg mit ihrer Umgebung / aufgenommen durch C. L. Gerling. Topographisch dargest. durch A. von Gironcourt. - [S.l.]. - 1 Kt. Standort: Universität Marburg, Universitätsbibliothek. - Signatur: VIII A 128 ph #K [10]. - Bemerkungen: (Hassiaca) Digitalisiert 2022
title: Marburg
Creators: name: Anonym
Publisher: name: Philipps-Universität Marburg
Year: 2022
Subjects: Marburg
Geography & travel Germany
Landeskunde Deutschlands
Stadtplan

description: Elektronische Reproduktion von: Marburg. - Marburg : Elwert, 1896. - 1 Kt. ; 34 x 27. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: VIII C 128 qn #K [718]. - Bemerkungen: (Hassiaca) Digitalisiert 2022
title: Marburg
Creators: name: Anonym
Publisher: name: Philipps-Universität Marburg
Year: 2022
Subjects: Geography & travel Germany
Landeskunde Deutschlands
Marburg
Stadtplan

description: Elektronische Reproduktion von: Marburg. - Marburg : Elwert, 1894. - 1 Kt. ; 34 x 27. - Standort: Universität Marburg, Universitätsbibliothek. - Signatur: VIII C 128 qm #K [718]. - Bemerkungen: (Hassiaca) Digitalisiert 2022
title: DNA Aptamer Against Alzheimer’s β-Amyloid 42 Protein
Creators: name: Abasi, Keon
name: Alcoleas, Mariana
name: Kothale, Siya
name: Munyaneza, Joey
Publisher: name: Digital Repository at the University of Maryland
Year: 2025
Subjects: subject: First-Year Innovation and Research Experience (FIRE)
subject: Molecular Diagnostics
subject: Diagnostic aptamer
subject: Beta-amyloid 42
subject: Alzheimer’s disease

description: Alzheimer's disease is a chronic neurodegenerative disorder. Currently, there are 6.9 million cases in individuals aged 65+ in the US, with an expected rise to 13.8 million by 2060. Current diagnostic methods, such as spinal taps and brain scans, are invasive and not widely accessible, exacerbating public health inequities. Recently, antibody-based blood tests have been developed to detect Alzheimer's, but aptamer-based diagnostics can be a cheaper and more accessible alternative to these antibody-based diagnostics. This study aims to develop a DNA aptamer capable of binding to the β-amyloid 42 protein, a biomarker associated with Alzheimer's, for a wide range of potential diagnostic applications. We conducted positive and negative selections using a Ni-NTA bead-based in vitro selection method against a His-GST tagged β-amyloid 42 protein. During selection, we utilized asymmetric PCR and gel extraction to amplify the single-stranded DNA. Results indicated enrichment of target-binding sequences in early selection rounds, though we encountered issues with low yields from gel extraction. Future work includes optimizing gel extraction protocols, gel shift assays to measure binding affinity, and increasing selection stringency to enhance aptamer specificity and binding affinity. This research aims to further contribute to developing non-invasive, cost-effective diagnostic tools for early Alzheimer's detection, aligning with the broader goals of improving access to diagnostic resources for all.
La figura complessa del datore di lavoro per la sicurezza nelle università tra “vecchio” e “nuovo” diritto
Creators: name: Pascucci, Paolo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: Il saggio esamina la specifica disciplina italiana della salute e sicurezza sul lavoro nel settore delle università che risale ancora al d.m. n. 363/1998 nonostante che dal 2008 sia stata emanata una nuova regolamentazione generale della materia. In particolare si pone attenzione criticamente sulla figura del datore di lavoro per la sicurezza nell’università, sulla sua individuazione e sulle sue responsabilità, analizzando altresì le posizioni degli altri soggetti dai quali dipende la tutela della salute e della sicurezza dei lavoratori dell’università.
The essay examines the specific italian rules on health and safety at work in the university sector, which dates back to D.M. n. 363/1998 despite that since 2008 has been issued a new general regulation of the matter. In particular it arises critically focus on the figure of the employer for safety in university, its detection and its responsibilities, also analyzing the positions of the other parties which provide the protection of the health and safety of university workers.
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
Dos décadas de aplicación de la Ley 31/1995, de Prevención de Riesgos Laborales (LPRL): luces y sombras
Creators: name: Igartua Miró, María Teresa
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: El cumplimiento de dos décadas por parte de la Ley 31/1995, de 8 de noviembre, de Prevención de Riesgos Laborales, encargada de adecuar la normativa española a los dictados comunitarios, es buena ocasión para una valoración de conjunto del sistema implantado, con sus debilidades y fortalezas, acompañada de una serie de reflexiones sobre la oportunidad de introducir algunos cambios normativos y, de forma especial, la necesidad de un nuevo enfoque en este terreno que, sin olvidar la tutela frente al accidente de trabajo, venga centrado en la mejora constante de las condiciones de trabajo, el bienestar y la consideración de las características personales del trabajador. El cambio de perspectiva debe superar también una visión centrada de forma exclusiva en la norma jurídica, los controles y la represión para insistir en la sensibilización, la participación y la eficiencia, buscando instrumentos no legislativos que contribuyan a la aplicación eficaz de las políticas preventivas, en especial en las pequeñas empresas.
Compliance of two decades by the Law 31/1995 of 8 November, on Prevention of Occupational Risks, in charge of adapting Spanish legislation to Community dictates, is a good opportunity for an overall assessment of the implemented system, with its strengths and weaknesses, along with a series of consideration on the opportunity to introduce some regulatory changes and, especially, the need for a new approach in this area, without forgetting the protection against accidents at work, focused on improving constant working conditions, welfare and assessment of the personal characteristics of the worker. The change of perspective must also pass a vision centered exclusively on the legal standard, controls and repression to emphasize the awareness, participation and efficiency, seeking non-legislative instruments that contribute to the effective implementation of preventive policies, especially in small enterprises.
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
La cultura della sicurezza fra organizzazione e formazione - Presentazione
Creators: name: Leccese, Vito
name: Stolfa, Francesco
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: Presentazione del Convegno, organizzato dal Dipartimento di Giurisprudenza dell’Università di Bari “A. Moro” – Master in Gestione del lavoro e delle relazioni sindacali, si è tenuto a Bari, il 20 novembre 2015
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
Prevenzione, organizzazione e formazione. A proposito di un recente libro sulla sicurezza sul lavoro
Creators: name: Pascucci, Paolo
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: Traendo spunto da alcune riflessioni sul concetto di “cultura della sicurezza sul lavoro” e dalla presentazione di un recente libro sulla stessa materia curato da Gaetano Natullo, l’autore si interroga sulla ipotetica autonomia scientifica del diritto della sicurezza sul lavoro. Segnalando come la materia rappresenti un terreno privilegiato per l’analisi interdisciplinare, l’autore rileva in particolare l’esigenza di una maggiore attenzione da parte degli studiosi del diritto del lavoro sulla dimensione della prevenzione. Sottolineando inoltre come il carattere partecipato del sistema della sicurezza sul lavoro dischiuda interessanti prospettive anche per i nuovi scenari del diritto del lavoro, infine si sofferma sulla crescente importanza dell’organizzazione e della formazione nella sicurezza sul lavoro.
 Inspired by some reflections on the concept of “culture of safety at work” and by the presentation of a recent book on the same subject edited by Gaetano Natullo, the author wonders about the hypothetical scientific autonomy of safety at work law. Pointing out how the matter represents a priority area for interdisciplinary analysis, the author notes in particular the need for greater attention by scholars of labour law on the prevention dimension. Moreover, pointing out that the participatory dimension of the safety at work system outlines interesting perspectives for new scenarios of labour law, finally he focuses on the growing importance of organization and training in safety at work.
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
Paraphaenocladius undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Paraphaenocladius
Paraphaenocladius undetermined

description: Paraphaenocladius sp.
Notes
Morpho-molecular identification (GenBank ID: PQ 458064; PQ 458065). New record for Lithuania.
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
Adaptive sequential design for phase II single-arm oncology trials: an expansion of Simon’s design
Creators: name: Gao, Ping
name: Zhang, Weidong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Biotechnology
subject: Evolutionary Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Science Policy

description: Single-arm phase II trials are very common in oncology. A fixed sample trial may lack sufficient power if the true efficacy is less than the assumed one. Adaptive designs have been proposed in the literature. We propose a Simon’s design based, adaptive sequential design. Simon’s design is the most used fixed sample design for single-arm phase II oncology trials. A prominent feature of Simon’s design is that it minimizes the sample size when there is no clinically meaningful efficacy. We identify Simon’s trial as a special group sequential design. Established methods for sample size re-estimation (SSR) can be readily applied to Simon’s design. Simulations show that simply adding SSR to Simon’s design may still not provide desirable power. We propose some expansions to Simon’s design. The expanded design with SSR can provide even more power.
Thienemanniella undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Thienemanniella
Thienemanniella undetermined

description: Thienemanniella sp.
Notes
Morpho identification. New record for Lithuania.
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
Female leadership and corporate ESG performance: evidence from China
Creators: name: Sun, Ruize
Publisher: name: University of Chicago
Year: 2022

description: This paper pursues the first systematic investigation on the implication of Chinese female leaders in connection with environmental, social and governance (ESG) performance of their businesses. With a comprehensive firm-year dataset of ESG performance and financial variables that is complemented by person-level demographics, it shows: (a) Despite alternative measures and models, no relation is detected between female directors and overall ESG performance, which appears resulting from that female directors’ impact on the social and governance pillar offset each other. (b) Female managers’ contribution to overall ESG performance is unambiguously positive, which results from female managers’ impact on governance pillar. (c) No significant quantile heterogeneity is detected between the nomination of female leaders and overall ESG performance, though pillar-level impact of female leadership differs between the best and worst ESG performers. (d) No critical mass effect is detected under the DID framework.
La sicurezza sul lavoro e la cultura giuridica italiana fra vecchio e nuovo diritto
Creators: name: Albi, Pasqualino
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: L’autore sostiene la tesi della centralità e della prevalenza dell’azione di adempimento rispetto all’azione risarcitoria in relazione alla violazione dell’obbligo di sicurezza messo in atto dal datore di lavoro, una tesi che trova sostegno, prima di ogni altra argomentazione, in una insopprimibile esigenza di tutela della persona nel rapporto di lavoro, un’esigenza che non può essere soddisfatta, se non in una prospettiva che è quella del “fatto compiuto”, sul versante risarcitorio.
 Se l’effetto della tesi si riconnette prioritariamente al tema dell’effettività dei diritti fondamentali della persona nel rapporto di lavoro non sembra fuori luogo mettere in rilievo che, in ragione delle conseguenze sanzionatorie derivanti dalla violazione dell’obbligo di sicurezza, potrebbe essere la stessa impresa ad avere un chiaro interesse ad adottare modelli organizzativi fortemente orientati al profilo prevenzionale e, addirittura, a praticare standard di sicurezza superiori alla soglia minima legale.
 The Author states the thesis of the priority of the fulfillment safety action over the compentation for damages.
 This thesis is based on the irrepresibile need for personal protection in the workplace and is connected with the principle of effectiveness of employee rights. The study underlines that the employer could have interest of promoting the health of employees and also of adopting standards of quality and safety higher than the minimum legal levels.
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
Organizzazione, colpa e sicurezza sul lavoro. Dosimetria dell’impresa e della colpa di organizzazione
Creators: name: Losappio, Giuseppe
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: Solo l’affermazione della colpa di organizzazione, quale categoria autonoma rispetto alla colpa individuale, consente di scongiurare il duplice rischio che ogni defaillance organizzativa (ogni violazione del dovere di organizzare l’organizzazione) alimenti il rimprovero di colpa individuale e che qualsiasi profilo di colpa individuale si converta in un addebito di colpa per l’ente. Da questa premessa deriva che non si dà responsabilità ex art. 25- septies del d.lgs. 231/2001 se le dimensioni/struttura dell’impresa non imprimono al dovere di organizzare l’organizzazione una misura che trascende quella dell’interazione soggettiva a struttura semplice orizzontale, governata dal principio di affidamento, e quella dell’interazione soggettiva a struttura complessa, governata dal principio della delega di funzioni.
 The opinion that considers the “fault of organization” as an independent category with respect to the individual’s negligence avoids the double risk that any organizational failure (any violation of the duty to organize the organization) feeds the charge of individual responsibility and any individual negligence is converted into a charge of responsibility for the corporation. For these reason there should not be responsibility under art. 25 septies d.lgs. 231/2001 in the case that the size/structure of the enterprise does not impress to the duty to organize the security a measure that goes beyond the horizontal simple model of interaction (reliance principle) and the vertical simple model of interaction (principle of assignement)
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
L’organizzazione della sicurezza in alcune tipologie di lavoro revisionate dal Jobs Act
Creators: name: Pasquarella, Valentina
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: Il contributo si sofferma sull’importanza della dimensione organizzativa della prevenzione in relazione ad alcune tipologie contrattuali riordinate e revisionate dal d.lgs. n. 81/2015 in applicazione della l. n. 183/2014, evidenziando le criticità di alcune disposizioni del d.lgs. n. 81/2008 relative al campo di applicazione soggettivo della normativa.
 The paper focuses attention on the importance of the organizational dimension of prevention in relation to some contractual arrangements ordered e reviewed by Legislative Decree n. 81/2015 issued in application of the law n. 183/2014, highlighting the critical issues of some provisions of Legislative Decree n. 81/2008 on the subjective scope of the law.
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
Tutela della salute e sicurezza, benessere dei lavoratori e legalità: interconnessioni organizzative e giuridiche
Creators: name: Laforgia, Stella
Publisher: name: Diritto della sicurezza sul lavoro
Year: 2016

description: Il saggio si prefigge lo scopo di indagare il fondamento tecnico-giuridico della relazione intercorrente tra la tutela della salute/sicurezza dei lavoratori e la legalità, con particolare riguardo al lavoro pubblico. Il medium logico dell’ipotizzata relazione è costituito dal benessere organizzativo di cui si ricostruisce, a partire da un quadro normativo frammentario, la definizione, l’estensione semantica e le sue implicazioni giuridiche.
 The paper aims to investigate the technical and legal basis of the relationship between workers’ health and safety and legality, with particular regard to work in the public sector. The logical means means of the proposed relationship is represented by the organizational wellness whose definition, as well as the semantic extension and its legal implications, is built from a fragmented regulatory framework.
description: Diritto della sicurezza sul lavoro, N° 1 (2016)
A Study of Guidelines Development for the Promotion of Public Mind Among Students of Ban Pong Pa Primary School, Phitsanulok Primary Educational Service Area Office 2
Creators: name: Juntarat Sareekum
Publisher: name: Pibulsongkram Rajabhat University
Year: 2022
Subjects: Student Competency Development Activity
Public Mind
Primary school

description: Humanities and Social Sciences Journal of Pibulsongkram Rajabhat University, 16, 1, 55-64
Zalutschia undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Zalutschia
Zalutschia undetermined

description: Zalutschia sp.
Notes
Morpho identification. First record for Lithuania (Pliūraitė 1999).
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
Advanced knowledge on Synthetic Data Generation Using GANs for Medical Imaging Applications
Creators: name: Researchscholar
Publisher: name: Zenodo
Year: 2025

description: Medical imaging is a cornerstone of modern diagnostics and treatment planning. However, the development of robust and accurate artificial intelligence models in this domain is limited by the scarcity of annotated medical images, data privacy constraints, and class imbalance in disease prevalence. Generative Adversarial Networks (GANs) offer a powerful solution to these challenges by synthesizing high-quality, realistic medical images that can augment existing datasets. This paper explores the foundational technologies behind GANs and their application in generating synthetic medical images for tasks such as classification, segmentation, and anomaly detection. It discusses various GAN architectures, including conditional GANs, CycleGANs, and StyleGANs, and how they are tailored for specific medical imaging modalities like MRI, CT, and X-rays. Use cases in radiology, oncology, dermatology, and ophthalmology are examined, highlighting improvements in model generalizability and diagnostic performance. Real-world studies demonstrate the impact of GAN-based synthetic data on reducing annotation effort and improving AI model robustness. Ethical considerations, including data authenticity, clinical trust, and regulatory challenges, are critically addressed. Finally, the paper outlines technical limitations such as mode collapse and anatomical fidelity, and presents future directions including explainable synthetic image generation, federated GANs, and integration into clinical workflows. GAN-driven synthetic data generation holds transformative potential in democratizing access to high-quality medical imaging datasets for AI research and application.
title: Generating Functions for Horses
Creators: name: Schreyer, Benjamin
Publisher: name: Digital Repository at the University of Maryland
Year: 2025
Subjects: subject: Generating Functions
subject: Weak Ordering
subject: Combinatorics

description: Before the photo-finish, ties were common in races. With ties we call these arrangements weak orderings. If we have n horses in a race we define that there are H(n) ways for the horses to be ranked. Further we want to more easily count outcomes of horse races where some horses have ”rigged”the race.
Legal Ontology for Nexus: Water, Energy and Food in EU Regulations
Creators: name: Rahman, Md Mizanur <1980>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2016
Subjects: IUS/20 Filosofia del diritto

description: The objectives of the thesis are – (a) to identify the problems in water-energy-food nexus from ICT and Law point of view and to propose theoretically a legal knowledge framework for water-energy-food nexus in order to reduce those problems technologically, (b) to construct and implement legal ontology for nexus extracted from EU water, energy and food Regulations in OWL 2 language, which is a part of the grater work of implementing legal knowledge framework for water-energy-food nexus proposed through the compilation of objective (a). Considering these objectives, this thesis presents total five chapters. First chapter investigates current start of art of nexus in order to identify (1) major knowledge gaps in the nexus and (2) ontological existence of the nexus in the EU regulations, particularly in the legal definitions accommodated in EU Regulations and Directives associated with nexus domains. It also rationalizes the need for legal ontology for nexus. Second chapter evaluates existing perspectives and methodologies available for constructing legal ontology. The purpose of such evaluation was to select correct perspective and methodology for constructing legal ontology for nexus. It, at the end, justifies the need for developing new methodology for constructing the legal ontology for nexus. Third chapter explains the methodology used for engineering legal definitional knowledge extracted from the selected EU regulations in order to construct the legal ontology for nexus. Fourth chapter explains in detail the legal ontology for nexus while fifth chapter evaluates legal ontology for nexus. In addition, conclusion of the thesis shares critical issues faced throughout this doctoral thesis work. Furthermore, annexes contain a list of all formulas of restrictions implemented in legal ontology for nexus and links of all modules of legal ontology for nexus. LODE documentation of the legal ontology for nexus is available at http://codexml.cirsfid.unibo.it/post-doctoralresearchers/mizanur-rahman/.
Cladopelma undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Cladopelma
Cladopelma undetermined

description: Cladopelma sp.
Notes
Morpho identification. First record for Lithuania (Ashe and Cranston 1990).
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
title: Nutrient Uptake Shifts During T4 Phage Replication in Escherichia coli
Creators: name: Goodwin, Gabriel
name: Altberger, Hannah
name: Varghese, Riya
Publisher: name: Digital Repository at the University of Maryland
Year: 2025
Subjects: subject: FIRE
subject: Microbiology
subject: FOS: Biological sciences
subject: Virology

description: The rising threat of antibiotic resistance has prompted renewed interest in alternative therapies, such as phage therapy. Phage therapy offers a targeted approach by lysing specific bacterial hosts, potentially circumventing antibiotic resistance. Our study investigates the host-pathogen interaction between Escherichia coli and T4 bacteriophage, a virus that targets only E. coli, with a focus on metabolic changes during infection. E. coli relies on various carbon sources to fuel its metabolic pathways, and viral infection can reprogram host metabolism to prioritize viral replication, often depleting cellular energy and nucleotide pools. Previous studies on other viruses have shown variable dependence on nutrients such as glucose and glutamine for replication. To determine nutrient utilization by T4 phage, uptake assays adapted for bacterial cells were conducted to examine glucose and glutamine consumption in uninfected versus phage-infected E. coli cells. Infected cells showed a marked increase in uptake of both glucose and glutamine, suggesting that both are critical for efficient viral replication. Ongoing research using glutaminase and glutamine synthetase knockout strains will help clarify the specific roles of these pathways in supporting phage propagation.
Model-Based Heuristics for Combinatorial Optimization
Creators: name: Rocchi, Elena <1986>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2016
Subjects: INF/01 Informatica

description: Many problems arising in several and different areas of human knowledge share the characteristic of being intractable in real cases. The relevance of the solution of these problems, linked to their domain of action, has given birth to many frameworks of algorithms for solving them. Traditional solution paradigms are represented by exact and heuristic algorithms. In order to overcome limitations of both approaches and obtain better performances, tailored combinations of exact and heuristic methods have been studied, giving birth to a new paradigm for solving hard combinatorial optimization
problems, constituted by model-based metaheuristics. In the present thesis, we deepen the issue of model-based metaheuristics, and present some methods, belonging to this class, applied to the solution of combinatorial
optimization problems.
L'impact de la structure hiérarchique sur la dissimulation des connaissances entre les médecins et les infirmiers dans les services cliniques du Centre Hospitalier Universitaire de Brazzaville
Creators: name: BANZOUSSI NIAKA, Ursule Nudy
name: TOKI, Rose
name: ABOUTOU ANNIE, Paule- Carole Tedji
Publisher: name: Zenodo
Year: 2024
Subjects: Structure hiérarchique ; dissimulation des connaissances ; facteurs de la hiérarchie inférieure ; facteurs de la hiérarchie supérieure ; facteurs du même niveau hiérarchique

description: Cet article examine l’impact de la structure hiérarchique sur la dissimulation des connaissances entre les médecins et les infirmiers au sein des services cliniques du centre hospitalier universitaire de Brazzaville. Les résultats d’une étude exploratoire auprès de 25 médecins et infirmiers révèlent que les facteurs issus des différentes hiérarchies, impactent la dissimulation des connaissances entre médecins et infirmiers.  Les facteurs de la hiérarchie inférieure tels que les relations d’équipe, la structure de l’équipe ainsi que les système et structure organisationnels influencent la dissimulation des connaissances ascendantes. De même, les pratiques cliniques, l’hégémonie médicale et la structure organisationnelle comme facteurs de la hiérarchie supérieure influencent la dissimulation des connaissances descendantes.  En outre, les facteurs du même niveau hiérarchique tels que le prestataire des soins (médecin ou infirmier) et l’autorisation de la consultation libérale des agents, influencent la dissimulation des connaissances entre collègues. Ces résultats suggèrent des orientations pour les décideurs politiques, managers et organisations désireux de soutenir la collaboration interprofessionnelle en vue d’optimiser le transfert de connaissances.
Epistemología y metodología de la investigación sociológica: reflexiones críticas de nuestras prácticas de investigación
Creators: name: Vanessa Hidalgo Calugullin, Ingrit
Publisher: name: unknown
Year: 2023

description: La construcción de productos sociológicos se basa en estrategias multimétodo, donde se utiliza tanto la metodología cuantitativa como la cualitativa, con un enfoque positivista/neopositivista y una perspectiva epistemológica. Sin embargo, se observa una falta de reflexión crítica y una baja discusión epistemológica y metodológica en la investigación de posgrado. Además, se tiende a utilizar solo aquellos datos que concuerdan con las hipótesis iniciales, descartando los casos que contradicen estas hipótesis. Esto limita la imaginación sociológica y la capacidad de descubrir nuevos
Coinductive Techniques on a Linear Quantum λ-Calculus
Creators: name: Rioli, Alessandro <1967>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2016
Subjects: INF/01 Informatica

description: In this thesis, it is examined the issue of equivalence between linear terms in higher order languages, that is, in languages which allow to use functions as variables, and where variables which appear in the terms must be used exactly once.  
The work is developed focusing on the bisimulation method, with the purpose to compare this technique with that which has become the standard for the comparison between the terms of a language, i.e. the context equivalence.
The thesis is divided into three parts: in the first one, the introduction of the bisimulation and context equivalence techniques takes place within a  deterministic linear and typed language.
In the second part, the same techniques are reformulated for a language that, while preserving the  linearity, loses the deterministic connotation, allowing the terms to evaluate to a set of values each one having a certain probability to appear in the end of calculation. In the last part, a quantum language is examined, discussing the advantages of quantum computation, which allows to speed-up many of the algorithms of computation. Here one  gives the concept of quantum program, which is inextricably linked to the (quantum) register where the qubits used in the computation are stored, entailing a more complex notion of equivalence between terms. 
The techniques to demonstrate that bisimulation is a congruence are not standard and have been used for the first time by Howe for untyped languages: within the thesis, one shows that bisimulation is a congruence in all considered languages but  it coincides with the  context equivalence relation only for the deterministic one. Indeed, extending the techniques already used by Howe to the probabilistic and quantum environment, it is shown, as non trivial result, that in probabilistic and quantum linear languages the bisimulation is contained in context equivalence relation.
Epistemología y metodología de la investigación sociológica: reflexiones críticas de nuestras prácticas de investigación
Creators: name: Vanessa Hidalgo Calugullin, Ingrit
Publisher: name: Humanities Commons
Year: 2023

description: La construcción de productos sociológicos se basa en estrategias multimétodo, donde se utiliza tanto la metodología cuantitativa como la cualitativa, con un enfoque positivista/neopositivista y una perspectiva epistemológica. Sin embargo, se observa una falta de reflexión crítica y una baja discusión epistemológica y metodológica en la investigación de posgrado. Además, se tiende a utilizar solo aquellos datos que concuerdan con las hipótesis iniciales, descartando los casos que contradicen estas hipótesis. Esto limita la imaginación sociológica y la capacidad de descubrir nuevos
Cryptotendipes undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Cryptotendipes
Cryptotendipes undetermined

description: Cryptotendipes sp.
Notes
Morpho identification. First record for Lithuania (Sæther and Spies 2005).
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
Fighting Cancer through Designed and Natural Products: Discovery of New LDH-A Inhibitors and Route to the Total Synthesis of Rakicidin A
Creators: name: Rupiani, Sebastiano <1988>
Publisher: name: Alma Mater Studiorum - Università di Bologna
Year: 2016
Subjects: CHIM/08 Chimica farmaceutica

description: The present work aimed to synthesizing new biologically active small molecules as innovative antitumor lead candidates and to the total synthesis of a natural compound with selectivity towards cancer hypoxia.
In this context, a first project involved the design and synthesis of N-acylhydrazone based inhibitors of lactate dehydrogenase A (LDH-A). The structures of the new molecules where designed by means of virtual screening and synthesized to obtain a library of analogs which were evaluated on the enzyme. Active compounds were also screened on cells of non-Hodgkins lymphoma and one of them proved to be a promising inhibitor, suggesting that the N-acylhydrazone as suitable scaffolds for LDH-A inhibitors.
The second project aimed to the synthesis of Galloflavin (GF) analogs and to the study of the compound’s SAR. GF is an LDH-A inhibitor which was previously identified and synthesized by our group. Its poor solubility and stability prevented us from studying its SAR maintaining the core structure. Therefore, the synthesis of three potential classes of structural analogs was devised and carried out. One compound was found to reproduce GF’s behaviour on the enzyme and in cell, therefore being a good starting point for the study. A small library of analogs was synthesized and biological tests are ongoing to acquire in-depth knowledge about the key pharmacophores of this interesting inhibitor.
The third project was carried out at Aarhus University in the group of Prof. Thomas Poulsen. The work focused on the total synthesis of Rakicidin A, a macrolide of natural origin which was identified and isolated from soil samples and is known for its interesting properties in selectively inducing cell death in hypoxic environments and being also active on cancer stem cells. The total synthesis involved several steps including key enantioselective reactions to build the 5 stereocenters on the molecule.
Microtendipes undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Microtendipes
Microtendipes undetermined

description: Microtendipes sp.
Notes
Morpho-molecular identification (GenBank ID: PQ 458129). First record for Lithuania (Grigelis 1999).
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
Amplification in Camelus dromedarius of microsatellite markers from Lama pacos (Master thesis)
Creators: name: NOUAIRIA, Ghada
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 300999
subject: Veterinary sciences not elsewhere classified

description: Progress in genetic researches about dromedaries is very limited compared to other breeding species. Thus, microsatellite markers defined for this specie are restricted.In this context, this survey tests 9 microsatellite markers that have been isolated in Lama alpaca on south Tunisian Camelus dromedarius DNA, to assess the possibility of using them as genetic markers. Experiment used different PCR conditions; variable temperatures and diverse MgCl2 concentrations. Two loci haven’t been able to amplify, suggesting there absence on the dromedary DNA. Three others amplified in a non specific way, whatever fusion temperature we used. At last, four microsatellites successfully amplified, the accurate PCR conditions and the size range for each one have been identified.Testing these microsatellites on 32 dromedary DNA samples shows that all four are polymorphic at a confidence interval of 95%. The mean heterozygosis was limited to 0.33, showing a deficit in heterozygosis, especially for the markers: P193 and P135. PIC values ranged from 0.11 to 0.65, showing a high informative level for PCTD17 and P132, but a low one for P135 and P193. Finally, Hardy-Weinberg equilibrium was satisfied in the loci: PCTD17 and P193.
Epistemología y metodología de la investigación sociológica: reflexiones críticas de nuestras  prácticas de investigación
Creators: name: Zúñiga, Camila
Publisher: name: Humanities Commons
Year: 2023

description: En el artículo elaborado por Robertt & Lisdero se aborda la falta de reflexión epistemológica y metodológica en la investigación sociológica, destacando la influencia del positivismo/neopositivismo y del vector epistemológico. Se sugiere la necesidad de considerar aperturas epistemológicas y metodológicas, como enfoques alternativos, cuestionamiento del sentido común y el uso de procedimientos analíticos diversos
The Dynamic Behaviour Of Railway Vehicles With Solid Rubber Tyres
Creators: name: Iwnicki, Simon
Publisher: name: London South Bank University
Year: 1991

description: Mathematical models have been developed and computer programs written to simulate the dynamic behaviour of typical underground railway vehicles used in coal mines. Equipment has been designed and constructed to allow the required track and wheel data to be collected for input to the models. Both linear and non-linear simulations have been carried out using these models and the results have been validated by full size vehicle tests.
Railway vehicles with solid rubber tyres running on steel rails are in common use underground in British coal mines where the additional traction offered by a rubber tyre over a steel wheel is useful. The particular problem of the tangential forces in the contact patch of a solid rubber tyre has been examined both practically and theoretically. The results have been compared with those predicted by theory for steel wheels and for pneumatic tyres and some similarities have been established. A theory for this case has been set up and confirmed by tests on a scale roller rig.
The new theory has been used together with the mathematical models to investigate fully the dynamic behaviour of the tyred locomotive. After initial validation of the techniques with tests on a full size vehicle the model has been used to analyse the design of the tyre itself. A new tyre design is suggested with a coned tread profile instead of the normal cylindrical profile. The predicted performance of this design was checked with the scale roller rig and the improved dynamic performance confirmed.
It is hoped that use of tyres of this type will increase, possibly with an internal polymer fill, to reduce hysteresis heating effects. Higher speeds as a result of the improved dynamic performance would encourage the use of solid rubber tyres on a wider range of rail vehicles.
Polypedilum undetermined
Creators: name: Stasiukynas, Laurynas
name: Laurindo da Silva, Fabio
name: Havelka, Jekaterina
name: Podėnas, Sigitas
name: Lekoveckaitė, Aistė
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Chironomidae
Polypedilum
Polypedilum undetermined

description: Polypedilum sp.
Notes
Morpho-molecular identification (GenBank ID: PQ 458150). First record for Lithuania (Lapinskaitė 1968).
description: Published as part of Stasiukynas, Laurynas, Laurindo da Silva, Fabio, Havelka, Jekaterina, Podėnas, Sigitas & Lekoveckaitė, Aistė, 2024, Chironomidae (Diptera) of the Šventoji and Žeimena sub-basins in Lithuania, pp. e 130218 in Biodiversity Data Journal 12 on page e130218, DOI: 10.3897/BDJ.12.e130218
TALABALARDA MA'NAVIY YETUKLIKNI SHAKLLANTIRISHNING PEDAGOGIK-PSIXOLOGIK XUSUSIYATLARI
Creators: name: Donayeva, Nozimaxon
Publisher: name: Zenodo
Year: 2024

description: Ushbu maqolada axborot muhiti sharoitida talabalarda ma’naviy yetuklikni shakllantirish xususida bayon etilgan. Shaxsning ma’naviy yetukligini belgilab beruvchi xususiyatlar shaxs yetukligini anglatuvchi bazaviy mezonlar, ma’naviy yetuklikni shakllantirishda talabalarda bo’lishi lozim bo’lgan ma’naviy-axloqiy  kompetensiya (fazilat)lar haqida ma’lumot berilgan. Talabalarning axborotdan to‘g‘ri  foydalana olish kompetensiyasini shakllantirishda ma’naviy yetuklik ko‘nikmalarini tarkib toptirishda ma’lum tavsiyalar berib o’tilgan.
同时检测胎儿染色体非整倍体和单基因疾病的一种新的无创产前检测方法
Creators: name: WU, YUJING
Publisher: name: CNGB
Year: 2022
Subjects: Raw sequence reads
Multiisolate
Medical

description: 基于TAGs-seq和孕妇血浆无创检测孕妇胎儿染色体非整倍体、ACH疾病和HBB的父源突变。TAGs-seq无创检测方法能较好平衡染色体分析和单基因病分析的数据要求，并降低流产的风险。同时该方法对于其他显性单病、隐性单基因遗传的父源突变或者denovo疾病的检测具有借鉴意义。
生殖道微生态变化与 HPV 感染研究 (Research on vaginal microbiome and HPV infection)
Creators: name: 杨中舟(Yang Zhongzhou)
Publisher: name: CNGB
Year: 2022
Subjects: Metagenome
Metagenomic assembly
Other
Clinical dataset
Multispecies

description: 考虑到目前生殖道微生态检测灵敏度较低，并缺乏系统性的 HPV 感染与生殖道微生物研究；我们据此开展此项研究。现有研究虽然报道生殖道微生态菌群与 HPV 阳性恶化的关联性，但目前未有研究系统性地探索行为因素与生殖道微生态菌群的关联性。 本项目作为首个系统性地探究行为因素，HPV 感染与生殖道菌群的研究。 English version: Considering the low sensitivity of current vaginal microbiome assays and the lack of systematic studies on HPV infection and reproductive tract microbiology; we conducted this study to address this issue. Although existing studies have reported the association of reproductive tract microflora with HPV infection, few studies have systematically explored the association of behavioral factors with reproductive tract microflora. This project is systematically investigating behavioral factors, HPV infection and reproductive tract flora.
A global survey of the full-length transcriptome of cabbage (Brassica oleracea var. capitata L.) based on SMRT sequencing
Creators: name: 季家磊(Jialei Ji)
Publisher: name: CNGB
Year: 2022
Subjects: Raw sequence reads
Transcriptome or Gene expression
Monoisolate

description: Cabbage (Brassica oleracea L. var. capitata L.) is an important biennial vegetable crop. Previous studies on gene transcripts of cabbage were mainly based on next-generation sequencing technology, which has limited scope to provide accurate transcript assembly. To analyze the whole transcriptome of cabbage at the isoform level, the PacBio Iso-Seq technology was used for a global survey of the full-length transcriptome of five tissues (root, stem, leaf, flower and silique) of cabbage.
Morphological and histochemical changes in the intestine of adult catfish (Lophiosilurus alexandri) subjected to chronic fasting and refeeding
Creators: name: Paschoalini, Alessandro Loureiro
name: Boaventura, Túlio Pacheco
name: Dos Santos, Fabio Aremil Costa
name: Bazzoli, Nilo
name: Luz, Ronald Kennedy
name: Favero, Gisele Cristina
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Compensatory growth is a feeding management strategy well documented in the literature. However, the molecular and histological effects on fish still require further knowledge. This study determined the biometric, morphological, and histometric changes in adults of catfish (Lophiosilurus alexandri) after chronic fasting. Sixty adults (396.6 ± 77.5 g) were tagged with microchips and distributed in two tanks (n = 30/tank), one with normal feed and the other with total food restriction for 60 d and then refed for another 15 d. Tissue and biometric samples were taken on days 20, 40, 60 and 75. Fish reared under chronic fasting presented weight loss and had significantly lower intestinal villi height, goblet cells and muscularis thickness than those fed on a control diet. In summary, a chronic food restriction protocol can change morphology and the 15-d refeeding period was not enough to reestablish the morphological parameters and weight of L. alexandri.
地贫治疗
Creators: name: 晓静 徐
Publisher: name: CNGB
Year: 2022
Subjects: Transcriptome or Gene expression
Monoisolate

description: 利用转基因技术，体外改造地贫病人来源的动员外周血造血干细胞，通过回输到病人体内，使其恢复正常造血功能。