cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The semiclassical propagator in fermionic Fock space
Creators: name: Engl, Thomas
name: Plößl, Peter
name: Urbina, Juan Diego
name: Richter, Klaus
Publisher: name: arXiv
Year: 2014
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Atomic Physics (physics.atom-ph)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We present a rigorous derivation of a semiclassical propagator for anticommuting (fermionic) degrees of freedom, starting from an exact representation in terms of Grassmann variables. As a key feature of our approach the anticommuting variables are integrated out exactly, and an exact path integral representation of the fermionic propagator in terms of commuting variables is constructed. Since our approach is not based on auxiliary (Hubbard-Stratonovich) fields, it surpasses the calculation of fermionic determinants yielding a standard form $\int {\cal D}[ψ,ψ^{*}] {\rm e}^{i R[ψ,ψ^{*}]}$ with real actions for the propagator. These two features allow us to provide a rigorous definition of the classical limit of interacting fermionic fields and therefore to achieve the long-standing goal of a theoretically sound construction of a semiclassical van Vleck-Gutzwiller propagator in fermionic Fock space. As an application, we use our propagator to investigate how the different universality classes (orthogonal, unitary and symplectic) affect generic many-body interference effects in the transition probabilities between Fock states of interacting fermionic systems.
description: 20 pages, 1 figure
Mechanisms of Severe Acute Respiratory Syndrome Pathogenesis and Innate Immunomodulation
Creators: name: Frieman, M.
name: Baric, R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: Summary: The modulation of the immune response is a common practice of many highly pathogenic viruses. The emergence of the highly pathogenic coronavirus severe acute respiratory virus (SARS-CoV) serves as a robust model system to elucidate the virus-host interactions that mediate severe end-stage lung disease in humans and animals. Coronaviruses encode the largest positive-sense RNA genome of ∼30 kb, encode a variety of replicase and accessory open reading frames that are structurally unique, and encode novel enzymatic functions among RNA viruses. These viruses have broad or specific host ranges, suggesting the possibility of novel strategies for targeting and regulating host innate immune responses following virus infection. Using SARS-CoV as a model, we review the current literature on the ability of coronaviruses to interact with and modify the host intracellular environment during infection. These studies are revealing a rich set of novel viral proteins that engage, modify, and/or disrupt host cell signaling and nuclear import machinery for the benefit of virus replication.
Phillips Laboratory Building Site, Charlene Avenue and Aberdeen Drive, Kirtland Air Force Base, New Mexico
Creators: name: Butler, William B.
Year: 1992
Subjects: subject: Bernalillo (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3646/bernalillo-county
subject: Albuquerque, New Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/84765/albuquerque-new-mexico
subject: Kirtland Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/17943/kirtland-air-force-base
subject: Historic
valueUri: https://core.tdar.org/browse/temporal-keyword/5728/historic
subject: Phillips Laboratory Reorganization and Consolidation Effort
valueUri: https://core.tdar.org/browse/other-keyword/168048/phillips-laboratory-reorganization-and-consolidation-effort
subject: Construction
valueUri: https://core.tdar.org/browse/other-keyword/78740/construction
subject: Surface Survey
valueUri: https://core.tdar.org/browse/other-keyword/4228/surface-survey
subject: Consultation
valueUri: https://core.tdar.org/browse/investigation-type/4/consultation
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: This report presents the results of an archaeological survey in support of the construction of a proposed building related to the nation-wide Phillips Laboratory Reorganization and Consolidation Effort. No cultural resources were encountered during the survey.
Dynamics and relaxation of sp biexcitons in disk-shaped quantum dots
Creators: name: Moldoveanu, V.
name: Dinu, I. V.
name: Dragomir, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We study the effects of intraband relaxation processes on optical manipulation protocols for sp biexcitons hosted by CdTe disk-shaped quantum dots. The many-body states are calculated within the configuration interaction method starting from single-particle states given by the kp theory. The time-dependent occupations of relevant many-body states are extracted from the von Neumann-Lindblad equation for the density operator. We mainly investigate the generation of sp biexcitons with two pulses of different polarizations sigma_{+} and sigma_{-}. The fast hole relaxation processes prevent a high-fidelity controlled operation on sp biexcitons and lead to the occupation of some transient states which can be optically probed. More importantly, the many-body structure of the transient states consists of two holes on the $s$ shell and antiparallel sp triplet states for electrons. Our simulations show that these triplet states are more stable against decoherence as they can only be damaged through slow electron relaxation. The configuration mixing due to correlation effects is also discussed.
description: 10 pages, 7 figures
Is the pseudogap a topological state?
Creators: name: Vargas-Paredes, Alfredo. A.
name: Cariglia, Marco
name: Doria, Mauro M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We conjecture that the pseudogap is an inhomogeneous condensate above the homogeneous state whose existence is granted by topological stability. We consider the simplest possible order parameter theory that provides this interpretation of the pseudogap and study its angular momentum states. The normal state gap density, the breaking of the time reversal symmetry and the checkerboard pattern are naturally explained under this view. The pseudogap is a lattice of skyrmions and the inner weak local magnetic field falls below the experimental threshold of observation given by NMR/NQR and $μ$SR experiments.
description: 12 pages, six figures, one table
Optimization of extraction of loquat flowers polyphenolics and its antioxidant and anti-polyphenol oxidase properties
Creators: name: Huang, Gui-Li
name: Ma, Jia-Jia
name: Sui, Si-Yao
name: Wang, Yu-Ning
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Molecular Biology
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: In this study, the conditions of extraction of loquat flowers polyphenolics were optimized through response surface methodology (RSM). Proper extraction conditions were: solid to liquid ratio 1 g per 50 mL and ethanol concentration 50% at 61°C for 9 min. Furthermore, the antioxidant and anti-polyphenol oxidase (PPO) activity of purified total polyphenolics (PTP) were investigated. PTP displayed strong antioxidant activity with IC50 values of 126.3 ± 8.9, 162.4 ± 6.3 and 94.97 mg ascorbic acid equivalent/g dry weight (mg AAE/d.w.) for ABTS, DPPH, and FRAP assays. In addition, PTP has a substantial inhibitory activity on PPO (IC50 = 115 ± 9.2 μg/mL). From the kinetics analysis, it was proved to be a reversible and mixed-type inhibitor of PPO with KI and KIS values of 76.77 μg/mL and 227.86 μg/mL, respectively. Further, the molecular mechanism underlying the inhibition of PPO by PTP was investigated by molecular docking techniques. The results showed that PTP units could form interaction with the catalytic pocket of PPO through the interaction with amino acid residues in the enzyme active center. The antioxidant activities of PTP together with its effect on PPO activity provide a strong starting point for their practical usage in the food industry.
What a Difference a Dalton Makes: Bacterial Virulence Factors Modulate Eukaryotic Host Cell Signaling Systems via Deamidation
Creators: name: Dangl, J. L.
name: Banfield, M. J.
name: Washington, E. J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Pathogenic bacteria commonly deploy enzymes to promote virulence. These enzymes can modulate the functions of host cell targets. While the actions of some enzymes can be very obvious (e.g., digesting plant cell walls), others have more subtle activities. Depending on the lifestyle of the bacteria, these subtle modifications can be crucially important for pathogenesis. In particular, if bacteria rely on a living host, subtle mechanisms to alter host cellular function are likely to dominate. Several bacterial virulence factors have evolved to use enzymatic deamidation as a subtle posttranslational mechanism to modify the functions of host protein targets. Deamidation is the irreversible conversion of the amino acids glutamine and asparagine to glutamic acid and aspartic acid, respectively. Interestingly, all currently characterized bacterial deamidases affect the function of the target protein by modifying a single glutamine residue in the sequence. Deamidation of target host proteins can disrupt host signaling and downstream processes by either activating or inactivating the target. Despite the subtlety of this modification, it has been shown to cause dramatic, context-dependent effects on host cells. Several crystal structures of bacterial deamidases have been solved. All are members of the papain-like superfamily and display a cysteine-based catalytic triad. However, these proteins form distinct structural subfamilies and feature combinations of modular domains of various functions. Based on the diverse pathogens that use deamidation as a mechanism to promote virulence and the recent identification of multiple deamidases, it is clear that this enzymatic activity is emerging as an important and widespread feature in bacterial pathogenesis.
Additional file 1 of Prominent astrocytic alpha-synuclein pathology with unique post-translational modification signatures unveiled across Lewy body disorders
Creators: name: Altay, Melek Firat
name: Liu, Alan King Lun
name: Holton, Janice L.
name: Parkkinen, Laura
name: Lashuel, Hilal A.
Publisher: name: figshare
Year: 2022
Subjects: Biochemistry
Medicine
Neuroscience
Pharmacology
Computational Biology

description: Additional file 1: Table S1. The primary and secondary antibodies included in this study. AC = autoclave; agg-aSyn = aggregated alpha-synuclein; aSyn = alpha-synuclein; FA = formic acid; GFAP = glial fibrillary acidic protein; Iba1 = ionized calcium binding adaptor protein 1; IF = immunofluorescence; IHC = immunohistochemistry; MBP = myelin basic protein; mc = monoclonal; mus = mouse; na = not applicable; NF = neurofilament; pc = polyclonal; rab = rabbit; SB = slot blot.
A microfluidic passive pumping Coulter counter
Creators: name: Walker, Glenn M.
name: McPherson, Amy L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: A microfluidic device using on-chip passive pumping was characterized for use as a particle counter. Flow occurred due to a Young-Laplace pressure gradient between two 1.2 mm diameter inlets and a 4 mm diameter reservoir when 0.5μ L fluid droplets were applied to the inlets using a micropipette. Polystyrene particles (10μm diameter) were enumerated using the resistive pulse technique. Particle counts using passive pumping were within 13% of counts from a device using syringe pumping. All pumping methods produced particle counts that were within 16% of those obtained with a hemocytometer. The effect of intermediate wash steps on particle counts within the passive pumping device was determined. Zero, one, or two wash droplets were loaded after the first of two sample droplets. No statistical difference was detected in the mean particle counts among the loading patterns (p > 0.05). Hydrodynamic focusing using passive pumping was also demonstrated.
USDA Forest Service Inventory Standards and Accounting Form: Negative Report - No Sites Present: Aerial Cable Site Fireline
Creators: name: Collazzi, Charlene
Year: 1999
Subjects: subject: Bernalillo (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3646/bernalillo-county
subject: Albuquerque, New Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/84765/albuquerque-new-mexico
subject: Kirtland Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/17943/kirtland-air-force-base
subject: Historic
valueUri: https://core.tdar.org/browse/temporal-keyword/5728/historic
subject: Prehistoric
valueUri: https://core.tdar.org/browse/temporal-keyword/53/prehistoric
subject: Fire Mitigation
valueUri: https://core.tdar.org/browse/other-keyword/168029/fire-mitigation
subject: Aerial Cables
valueUri: https://core.tdar.org/browse/other-keyword/168043/aerial-cables
subject: Cable Tower
valueUri: https://core.tdar.org/browse/other-keyword/168044/cable-tower
subject: Records Search / Inventory Checking
valueUri: https://core.tdar.org/browse/investigation-type/8/records-search-inventory-checking

description: USDA Forest Service Inventory Standards and Accounting Form for a survey in support the proposed Aerial Cable Site Fireline construction project.
Additional file 2 of Prominent astrocytic alpha-synuclein pathology with unique post-translational modification signatures unveiled across Lewy body disorders
Creators: name: Altay, Melek Firat
name: Liu, Alan King Lun
name: Holton, Janice L.
name: Parkkinen, Laura
name: Lashuel, Hilal A.
Publisher: name: figshare
Year: 2022
Subjects: Biochemistry
Medicine
Neuroscience
Pharmacology
Computational Biology

description: Additional file 2: Fig. S1. Specificity validation of the aSyn antibodies LASH-BL 34-45, LASH-BL 80-96 and BD SYN-1 by pre-adsorption followed by IHC on DLB1 cingulate cortex (layers V–VI). aSyn = alpha-synuclein; DLB = dementia with Lewy bodies; IHC = immunohistochemistry. Fig. S2. (a) A representative image of a cortical LB positive for NF and LASH-BL 34-45, and negative for GFAP. Image from DLB1 cingulate cortex taken using Zeiss LSM700 confocal microscope. (b) The oligodendrocytes and microglial cells, marked by anti-MBP and anti-Iba1 antibodies, respectively, were negative for aSyn in the white matter (upper two panels). Punctate aSyn positivity was detected in the microglial cells in the grey matter (lower panel) as rare events. Images taken from DLB1 cingulate cortex using Olympus slide scanner at 40x magnification. aSyn = alpha-synuclein; DLB = dementia with Lewy body; GFAP = glial fibrillary acidic protein; Iba1 = ionised calcium binding adaptor protein 1; MBP = myelin basic protein; LB = Lewy body; NF = neurofilament. Fig. S3. The cingulate cortex of sporadic PD, PDD, DLB, SNCA G51D mutation and SNCA duplication cases immunostained using antibodies against the N-terminal (LASH-EGTNter) and C-terminal (2F10-E12 and AB 134-138) of aSyn. Astrocytic aSyn was not detected using these antibodies. Representative images taken from cingulate cortical layers V–VI of PD7, PDD5, DLB1, SNCA G51D3 and SNCA duplication cases. aSyn = alpha-synuclein; DLB = dementia with Lewy bodies; PD = Parkinson’s disease; PDD = Parkinson’s disease with dementia. Fig. S4. Representative IF images of GFAP-positive astrocytes from DLB1, SNCA G51D3 and SNCA duplication cingulate cortices, showing positivity for aSyn detected using LASH-BL 34-45 antibody. Images taken using Olympus slide scanner at 40x magnification. aSyn = alpha-synuclein; DLB = dementia with Lewy body; GFAP = glial fibrillary acidic protein; IF = immunofluorescence; NF = neurofilament. Fig. S5. Representative images from the SNCA duplication EC, amygdala and insula immunostained using antibodies against the N-terminal, NAC and C-terminal regions of aSyn. The astrocytic aSyn detected only by LASH-BL34-45, LASH-BL80-96 and BD SYN-1 (91-99) antibodies. Similar staining patterns were observed in the same regions from PD, PDD, DLB and SNCA G51D cases stained with the same antibody set. aSyn = alpha-synuclein; DLB = dementia with Lewy bodies
Transit Light Curves with Finite Integration Time: Fisher Information Analysis
Creators: name: Price, Ellen M.
name: Rogers, Leslie A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: Kepler has revolutionized the study of transiting planets with its unprecedented photometric precision on more than 150,000 target stars. Most of the transiting planet candidates detected by Kepler have been observed as long-cadence targets with 30 minute integration times, and the upcoming Transiting Exoplanet Survey Satellite (TESS) will record full frame images with a similar integration time. Integrations of 30 minutes affect the transit shape, particularly for small planets and in cases of low signal-to-noise. Using the Fisher information matrix technique, we derive analytic approximations for the variances and covariances on the transit parameters obtained from fitting light curve photometry collected with a finite integration time. We find that binning the light curve can significantly increase the uncertainties and covariances on the inferred parameters when comparing scenarios with constant total signal-to-noise (constant total integration time in the absence of read noise). Uncertainties on the transit ingress/egress time increase by a factor of 34 for Earth-size planets and 3.4 for Jupiter-size planets around Sun-like stars for integration times of 30 minutes compared to instantaneously-sampled light curves. Similarly, uncertainties on the mid-transit time for Earth and Jupiter-size planets increase by factors of 3.9 and 1.4. Uncertainties on the transit depth are largely unaffected by finite integration times. While correlations among the transit depth, ingress duration, and transit duration all increase in magnitude with longer integration times, the mid-transit time remains uncorrelated with the other parameters. We provide code in Python and Mathematica for predicting the variances and covariances at www.its.caltech.edu/~eprice.
Biosensor Förster resonance energy transfer detection by the phasor approach to fluorescence lifetime imaging microscopy
Creators: name: Hinde, Elizabeth
name: Gratton, Enrico
name: Welch, Christopher
name: Hahn, Klaus M.
name: Digman, Michelle A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We present here the phasor approach to biosensor FRET detection by fluorescence lifetime imaging microscopy (FLIM) and show that this method of data representation is robust towards biosensor design as well as the fluorescence artifacts inherent to the cellular environment. We demonstrate this property on a series of dual and single chain biosensors which report the localization of Rac1 and RhoA activity, whilst performing concomitant ratiometric FRET analysis on the acquired FLIM data by the generalized polarization (GP) approach. We then evaluate and compare the ability of these two methods to quantitatively image biosensor FRET signal as a function of time and space. We find that with lifetime analysis in the phasor plot each molecular species is transformed into a two dimensional coordinate system where independent mixtures of fluorophores can be distinguished from changes in lifetime due to FRET. This enables the fractional contribution of the free and bound state of a dual chain biosensor or the low and high FRET species of a single chain biosensor to be quantified in each pixel of an image. The physical properties intrinsic to each biosensor design are also accurately characterized by the phasor analysis; thus this method could be used to inform biosensor optimization at the developmental stage. We believe that as biosensors become more sophisticated and are multiplexed with other fluorescent molecular tools, biosensor FRET detection by the phasor approach to FLIM will not only become imperative to their use but also their advancement.
Cultural Resources Survey: Laser Tracker Site, Sandia Ranger District, Cibola National Forest, Bernalillo County
Creators: name: Hayden, John S.
Year: 1988
Subjects: subject: Bernalillo (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3646/bernalillo-county
subject: Albuquerque, New Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/84765/albuquerque-new-mexico
subject: Kirtland Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/17943/kirtland-air-force-base
subject: Historic
valueUri: https://core.tdar.org/browse/temporal-keyword/5728/historic
subject: Prehistoric
valueUri: https://core.tdar.org/browse/temporal-keyword/53/prehistoric
subject: Negative Result
valueUri: https://core.tdar.org/browse/other-keyword/76495/negative-result
subject: Sol se Mete Canyon
valueUri: https://core.tdar.org/browse/other-keyword/168091/sol-se-mete-canyon
subject: Cibola National Forest
valueUri: https://core.tdar.org/browse/other-keyword/168073/cibola-national-forest
subject: Pedestrian Survey
valueUri: https://core.tdar.org/browse/other-keyword/9852/pedestrian-survey
subject: Sandia Ranger District
valueUri: https://core.tdar.org/browse/other-keyword/168042/sandia-ranger-district
subject: Cultural Resources Clearance
valueUri: https://core.tdar.org/browse/other-keyword/168090/cultural-resources-clearance
subject: Consultation
valueUri: https://core.tdar.org/browse/investigation-type/4/consultation
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: A cultural resources survey was done on 0.16 acres for a road and laser tracker pad within PLO 995 in Sol se Mete Canyon on the Sandia Ranger District of the Cibola National Forest. No evidence of archeological activity was found. Cultural resources clearance is recommended.
A model for simulating speckle-pattern evolution based on close to reality procedures used in spectral-domain OCT
Creators: name: Zaitsev, V. Yu.
name: Matveev, L. A.
name: Matveyev, A. L.
name: Gelikonov, G. V.
name: Gelikonov, V. M.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Medical Physics (physics.med-ph)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: A robust model for simulating speckle pattern evolution in optical coherence tomography (OCT) depending on the OCT system parameters and tissue deformation is reported. The model is based on application of close to reality procedures used in spectral-domain OCT scanners. It naturally generates images reproducing properties of real images in spectral-domain OCT, including the pixelized structure and finite depth of unambiguous imaging, influence of the optical spectrum shape, dependence on the optical wave frequency and coherence length, influence of the tissue straining, etc. Good agreement with generally accepted speckle features and properties of real OCT images is demonstrated.
description: 13 pages, 6 figures
Azevedo, A. - Granada, A. - Azevedo, E., O Povo Sacerdotal. Ed. do Secretariado da JAC. Vol. de 244 ps. 142x200. Braga 1968
Creators: name: Marques, José Silva
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
Arrays of high-aspect ratio microchannels for high-throughput isolation of circulating tumor cells (CTCs)
Creators: name: Milowsky, Matthew I.
name: Soper, Steven A.
name: Wang, Hong
name: Whang, Young E.
name: Hupert, Mateusz L.
name: Witek, Małgorzata A.
name: Jackson, Joshua M.
name: Kamande, Joyce
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: Microsystem-based technologies are providing new opportunities in the area of in vitro diagnostics due to their ability to provide process automation enabling point-of-care operation. As an example, microsystems used for the isolation and analysis of circulating tumor cells (CTCs) from complex, heterogeneous samples in an automated fashion with improved recoveries and selectivity are providing new opportunities for this important biomarker. Unfortunately, many of the existing microfluidic systems lack the throughput capabilities and/or are too expensive to manufacture to warrant their widespread use in clinical testing scenarios. Here, we describe a disposable, all-polymer, microfluidic system for the high-throughput (HT) isolation of CTCs directly from whole blood inputs. The device employs an array of high aspect ratio (HAR), parallel, sinusoidal microchannels (25 µm × 150 µm; W × D; AR = 6.0) with walls covalently decorated with anti-EpCAM antibodies to provide affinity-based isolation of CTCs. Channel width, which is similar to an average CTC diameter (12–25 µm), plays a critical role in maximizing the probability of cell/wall interactions and allows for achieving high CTC recovery. The extended channel depth allows for increased throughput at the optimized flow velocity (2 mm/s in a microchannel); maximizes cell recovery, and prevents clogging of the microfluidic channels during blood processing. Fluidic addressing of the microchannel array with a minimal device footprint is provided by large cross-sectional area feed and exit channels poised orthogonal to the network of the sinusoidal capillary channels (so-called Z-geometry). Computational modeling was used to confirm uniform addressing of the channels in the isolation bed. Devices with various numbers of parallel microchannels ranging from 50 to 320 have been successfully constructed. Cyclic olefin copolymer (COC) was chosen as the substrate material due to its superior properties during UV-activation of the HAR microchannels surfaces prior to antibody attachment. Operation of the HT-CTC device has been validated by isolation of CTCs directly from blood secured from patients with metastatic prostate cancer. High CTC sample purities (low number of contaminating white blood cells, WBCs) allowed for direct lysis and molecular profiling of isolated CTCs.
Cultural Resources Survey of the Madera Canyon Road Extension/DOE
Creators: name: Hayden, John S.
Year: 1986
Subjects: subject: Bernalillo (County)
valueUri: https://core.tdar.org/browse/geographic-keyword/3646/bernalillo-county
subject: Albuquerque, New Mexico
valueUri: https://core.tdar.org/browse/geographic-keyword/84765/albuquerque-new-mexico
subject: Sandia Ranger District
valueUri: https://core.tdar.org/browse/geographic-keyword/85840/sandia-ranger-district
subject: Cibola National Forest
valueUri: https://core.tdar.org/browse/geographic-keyword/17697/cibola-national-forest
subject: Kirtland Air Force Base
valueUri: https://core.tdar.org/browse/geographic-keyword/17943/kirtland-air-force-base
subject: AR 03-03-05-167
valueUri: https://core.tdar.org/browse/site-name/126769/ar-03-03-05-167
subject: Check Dam
valueUri: https://core.tdar.org/browse/site-type/1244/check-dam
subject: Negative Result
valueUri: https://core.tdar.org/browse/other-keyword/76495/negative-result
subject: Reconnaissance / Survey
valueUri: https://core.tdar.org/browse/investigation-type/7/reconnaissance-survey

description: This report documents the performance and findings of an archaeological survey conducted on approximately 7.6 acres of the Sandia Ranger District. A constructed feature, AR 03-03-05-167, composed of arranged rock and dirt fill was located in the area of the planned change in road alignment. This feature is very likely to have served as a check dam. Due to the lack of any cultural material onsite or other kinds of cultural resource sites within the vicinity, no cultural affiliation, classification, or time period could be assigned. Project was redesigned to avoid the check dam. No other evidence of cultural resources were found within the remainder of the proposed project area.
In a hard spot: Providing group prenatal care in two urban clinics
Creators: name: Knafl, Kathleen A.
name: Groce, Nora E.
name: Sadler, Lois S.
name: Kennedy, Holly Powell
name: Novick, Gina
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: AbstractObjectivesCenteringPregnancy (Centering) group prenatal care has been demonstrated to improve perinatal outcomes and provide a positive experience of care for women, but it can be difficult to implement and sustain in some clinical settings. The purpose of this study was to examine the challenges encountered when Centering group prenatal care was provided, and the responses of Centering group leaders to these challenges.Designthis was a longitudinal, qualitative study using interpretive description. Data collection included participant-observation and interviews with group leaders and women receiving group prenatal care.Settingtwo urban clinics providing care to low income women in the northeastern United States.Participantsinterview participants were 23 pregnant women (primarily African-American and Hispanic) receiving group prenatal care; other participants were 24 significant others and support staff participating in groups, and two nurse-midwife group leaders.Findingsthe clinics did not always provide full resources for implementing Centering as designed, creating numerous challenges for the group leaders, who were committed to providing group prenatal care. In an attempt to sustain the model in the face of these limitations, the group leaders made a number of compromises and modifications to the Centering model.Key conclusionsthe limited clinic resources and resulting modifications of the model had a number of downstream effects, some of which affected relationships within groups, participation, and group cohesion.Implicationsmodifications of the Centering model should be undertaken with caution. Strategies are needed to enhance the success and sustainability of Centering in varied clinical settings so that the benefits of the model, which have been demonstrated under more controlled circumstances, can be conferred to women receiving routine care during pregnancy.
Vários, Evangelización y catequesis; Que es la catequesis? Catequesis, educación de la fe. Ed. Marova. 3 Vol. de 210, 190 e 203 ps. 135x200. Madrid 1968
Creators: name: Tinoco, António Franklim Machado
Publisher: name: Theologica
Year: 1969

description: Theologica, v. 4 n. 2-3 (1969)
The Solar Twin Planet Search. I. Fundamental parameters of the stellar sample
Creators: name: Ramirez, I.
name: Melendez, J.
name: Bean, J.
name: Asplund, M.
name: Bedell, M.
name: Monroe, T.
name: Casagrande, L.
name: Schirbel, L.
name: Dreizler, S.
name: Teske, J.
name: Maia, M. Tucci
name: Alves-Brito, A.
name: Baumann, P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We are carrying out a search for planets around a sample of solar twin stars using the HARPS spectrograph. The goal of this project is to exploit the advantage offered by solar twins to obtain chemical abundances of unmatched precision. This survey will enable new studies of the stellar composition -- planet connection. Here we used the MIKE spectrograph on the Magellan Clay Telescope to acquire high resolution, high signal-to-noise ratio spectra of our sample stars. We measured the equivalent widths of iron lines and used strict differential excitation/ionization balance analysis to determine atmospheric parameters of unprecedented internal precision (DTeff=7K, Dlogg=0.019, D[Fe/H]=0.006dex, Dvt=0.016km/s). Reliable relative ages and highly precise masses were then estimated using theoretical isochrones. The spectroscopic parameters we derived are in good agreement with those measured using other independent techniques. The root-mean-square scatter of the differences seen is fully compatible with the observational errors, demonstrating, as assumed thus far, that systematic uncertainties in the stellar parameters are negligible in the study of solar twins. We find a tight activity-age relation for our sample stars, which validates the internal precision of our dating method. Furthermore, we find that the solar cycle is perfectly consistent both with this trend and its star-to-star scatter. We present the largest sample of solar twins analyzed homogeneously using high quality spectra. The fundamental parameters derived from this work will be employed in subsequent work that aims to explore the connections between planet formation and stellar chemical composition.
description: Astronomy and Astrophysics, in press
Physical activity during pregnancy and postpartum depressive symptoms
Creators: name: Dole, Nancy
name: Gaynes, Bradley N.
name: Demissie, Zewditu
name: Herring, Amy H.
name: Evenson, Kelly R.
name: Siega-Riz, Anna Maria
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: to examine the associations between total and domain-specific moderate-to-vigorous physical activity (MVPA) during pregnancy and postpartum depressive symptoms.
Dissecting the 3D structure of elliptical galaxies with gravitational lensing and stellar kinematics
Creators: name: Barnabè, Matteo
name: Spiniello, Chiara
name: Koopmans, Léon V. E.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: The combination of strong gravitational lensing and stellar kinematics provides a powerful and robust method to investigate the mass and dynamical structure of early-type galaxies. We demonstrate this approach by analysing two massive ellipticals from the XLENS Survey for which both high-resolution HST imaging and X-Shooter spectroscopic observations are available. We adopt a flexible axisymmetric two-component mass model for the lens galaxies, consisting of a generalised NFW dark halo and a realistic self-gravitating stellar mass distribution. For both systems, we put constraints on the dark halo inner structure and flattening, and we find that they are dominated by the luminous component within one effective radius. By comparing the tight inferences on the stellar mass from the combined lensing and dynamics analysis with the values obtained from stellar population studies, we conclude that both galaxies are characterised by a Salpeter-like stellar initial mass function.
description: Proceedings of the IAU Symposium 309, Contributed Talk, Vienna, July 2014; 4 pages, 2 figures
Additional file 1 of Machine learning techniques on homological persistence features for prostate cancer diagnosis
Creators: name: Rammal, Abbas
name: Assaf, Rabih
name: Goupil, Alban
name: Kacim, Mohammad
name: Vrabie, Valeriu
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1
A novel prognostic models for identifying the risk of hepatocellular carcinoma based on epithelial-mesenchymal transition-associated genes
Creators: name: Xiong, Chen
name: Wang, Guifu
name: Bai, Dousheng
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Several epithelial-mesenchymal transition (EMT)-associated genes (EAGs) have been confirmed to correlate with the prognosis of hepatocellular carcinoma (HCC) patients. Herein, we explored the value of EAGs in the prognosis of HCC relying on data from The Cancer Genome Atlas (TCGA) database. A total of 200 EMT-associated genes were downloaded from the Gene set enrichment analysis (GSEA) website. Moreover, 96 differentially expressed EAGs were identified. Using Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, we forecasted the potential molecular mechanisms of EAGs. To identify prognostic EAGs, Cox regression was used in developing a prognostic risk model. Then, the Kaplan-Meier and receiver operating characteristic (ROC) curves were plotted to validate the prognostic significance of the model. A total of 5 prognostic correlated EAGs (P3H1, SPP1, MMP1, LGALS1, and ITGB5) were screened via Cox regression, which provided the basis for developing a novel prognostic risk model. Based on the risk model, patients were subdivided into high-risk and low-risk groups. The overall survival of the low-risk group was better compared to the high-risk group (P < 0.00001). The ROC curve of the risk model showed a higher AUC (Area under Curve) (AUC = 0.723) compared to other clinical features (AUC ≤ 0.511). A nomogram based on this model was constructed to predict the 1-year, 2-year, and 3-year overall survival rates (OS) of patients. Conclusively, we developed a novel HCC prognostic risk model based on the expression of EAGs, which help advance the prognostic management of HCC patients. Abbreviations: HCC: hepatocellular carcinoma; TCGA: The Cancer Genome Atlas; EMT: epithelial-mesenchymal transition; EAGs: EMT-associated genes; GSEA: gene set enrichment analysis; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; PPI: protein-protein interaction; TF: transcription factor; ROC: receiver operating characteristic; K-M: Kaplan-Meier; AUC: the area under the ROC curve; FDR: false discovery rate; TNM: Tumor size/lymph nodes/distance metastasis
An Examination of Sociodemographic, Health, Psychological Factors, and Fruit and Vegetable Consumption Among Overweight and Obese U.S. Veterans
Creators: name: Ko, Linda K.
name: Armstrong-Brown, Janelle
name: Anthony, Tammy
name: Campbell, Marci K.
name: Valle, Carmina G.
name: Carr, Carol
name: Allicok, Marlyn
name: Dundon, Margaret
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: A diet high in fruits and vegetables (F&Vs) is associated with decreased risk for cardiovascular disease, diabetes, and cancer. This study investigated the relationship between sociodemographic, health, and psychosocial factors and F&V consumption among overweight and obese U.S. veterans. Participants were recruited from two Veterans Affairs medical center sites in 2005. Two hundred eighty-nine participants completed a self-administered survey. Bivariate and multivariate linear regression models were built to examine the association between sociodemographic, health, and psychosocial variables and F&V consumption. Older age (B = 0.01; p < 0.001) and being Black (B = −0.18; p < 0.05) were related to increased F&V consumption. Reported tobacco use was inversely associated with F&V consumption (B = −0.30; p < 0.01). Greater self-efficacy (B = 0.07; p < 0.05), fewer perceived barriers (B = −0.14; p < 0.01), and correct knowledge of recommended daily F&V intake (B = 0.12; p < 0.05) were related to eating more F&Vs. U.S. veterans disproportionately experience overweight and obese conditions. Age, race, tobacco use, and psychosocial factors should be considered carefully when developing dietary interventions among overweight and obese U.S. veterans.
title: Confronto fra l’apriorismo etico di Kant e l’apriorismo emozionale di Scheler
Creators: name: Parisi , Maria Letizia
Publisher: name: Roma Tre-Press
Year: 2012

description: I problemi dell'etica coincidono con l'indagine di quell'animale particolarissimo che è l'uomo, la cui natura non è ascrivibile né a una condizione di necessità assoluta né a una di libertà assoluta. Le risposte di Kant e Scheler circa la questione morale sono sicuramente in sintonia con lo spirito del loro tempo: il primo è uno spirito illuminista; il secondo si inoltra per un nuovo cammino, quello dell'antropologia filosofica.

description: B@belonline vol. 13 Chaos/Kosmos
Additional file 2 of Epidemiologic features, clinical characteristics, and predictors of mortality in patients with candidemia in Alameda County, California; a 2017–2020 retrospective analysis
Creators: name: Meyahnwi, Didien
name: Siraw, Bekure B.
name: Reingold, Arthur
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 2. Data dictionary, candidemia csv.
Rhizoremediation of Cu(II) ions from contaminated soil using plant growth promoting bacteria: an outlook on pyrolysis conditions on plant residues for methylene orange dye biosorption
Creators: name: Yaashikaa, P. R.
name: Kumar, P. Senthil
name: Varjani, Sunita
name: Saravanan, A.
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology
subject: 60506 Virology

description: Rhizoremediation is one of the most accepted, cost-effective bioremediation techniques focusing on the application of rhizospheric microorganisms in combination with plants for the remediation of organic and inorganic pollutants from the contaminated sites. This work focuses on isolation and identification of metal resistant bacteria to grow on medium with the copper ion concentration of 1500 mg/L. The resistant isolate was identified as Pantoea dispersa by a 16S rRNA sequencing. The bioaccumulation of Cu(II) ions in plant is high at the concentration of Cu(II) ion is 125 mg/L in soil. In Sphaeranthus indicus the Cu(II) ion translocation factor has expanded with an expansion of grouping of Cu(II) ion in the soil and the most extreme TF factor was acquired at the centralization of Cu(II) ion is 150 mg/L in soil. Surface morphology of biochar was characterized by Scanning Electron Microscopy (SEM) analysis. The adsorption performance of biochar (Sphaeranthus indicus biomass) and mechanism for the removal of Cu(II) ion were investigated. This study resolves that pyrolysis is promising technology for the conversion of metal ion contaminated plant residues from phytoremediation into valuable products.
Simulation and Measurement Based Vehicle-to-Vehicle Channel Characterization: Accuracy and Constraint Analysis
Creators: name: Abbas, Taimoor
name: Nuckelt, Jörg
name: Kürner, Thomas
name: Zemen, Thomas
name: Mecklenbräuker, Christoph
name: Tufvesson, Fredrik
Publisher: name: arXiv
Year: 2014
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: In this paper, a deterministic channel model for vehicle-to-vehicle (V2V) communication, is compared against channel measurement data collected during a V2V channel measurement campaign using a channel sounder. Channel metrics such as channel gain, delay and Doppler spreads, eigenvalue decomposition and antenna correlations are derived from the ray tracing (RT) simulations as well as from the measurement data obtained from two different measurements in an urban four-way intersection scenario. The channel metrics are compared separately for line-of-sight (LOS) and non-LOS (NLOS) situation. Most power contributions arise from the LOS component (if present) as well as from multipaths with single bounce reflections. Measurement and simulation results show a very good agreement in the presence of LOS, as most of the received power is contributed from the LOS component. In NLOS, the difference is large because the ray tracer is unable to capture some of the multi bounced propagation paths that are present in the measurements. Despite the limitations of the ray-based propagation model identified in this work, the model is suitable to characterize the channel properties in a sufficient manner.
description: 10 pages, 20 figures, Submitted for publication and is under review in IEEE Transactions on Antennas and Propagation, 2014
Cancer Incidence Among Patients of the U.S. Veterans Affairs Health Care System
Creators: name: Provenzale, Dawn T.
name: Thomas, Catherine M.
name: McNeil, Rebecca
name: Zullig, Leah L.
name: Jackson, George L.
name: Kelley, Michael J.
name: Dorn, Raye Anne
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Approximately 40,000 incident cancer cases are reported in VA Central Cancer Registry (VACCR) annually (~3% of United States cancer cases). Our objective was to provide the first comprehensive description of cancer incidence as reported in VACCR.
title: Modelling Velocity Profiles of Aerated Flows Down Grassed Spillways
Creators: name: Cui, H.
name: Felder, S.
name: Kramer, M.
Publisher: name: Utah State University
Year: 2022

description: The ecological and environmental benefits of grassed spillways present a green solution to the construction of low head conveyance structures. On a grassed spillway, the aggregate of the grass canopy and root structure may alter flow resistance, velocity distribution and other flow properties. While subcritical flows in vegetated open channels have been extensively researched, only little is known about flow properties in supercritical high-velocity flows, which are typically characterized by self-aeration. The current study explores the application of a velocity superposition to supercritical aerated flows on a spillway with artificial grass. Velocity measurements were conducted with a Pitot tube and a phase-detection conductivity probe, allowing for the extraction of shear velocities at the canopy top which revealed an additional free-stream velocity layer. A comparison of the mixing layer length scale with the shear length scale (of the mixing layer) demonstrated a good correlation. Overall, this study provided new insights into the flow resistance of supercritical flows on grassed spillways.