cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Combination of rituximab and low-dose glucocorticoids for idiopathic refractory nephrotic syndrome with MCD/FSGS: a single-center prospective cohort study
Creators: name: Yimamuyushan, Aikeda
name: Li, Youqi
name: Jiao, Wenwen
name: Yu, Jianwen
name: Li, Jianbo
name: Shi, Yongjun
name: Chen, Wei
name: He, Junbing
name: Liu, Qinghua
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Science Policy
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: The treatment of idiopathic refractory nephrotic syndrome (IRNS) remains a difficult problem in clinical practice. This study aims to determine the efficacy and safety of combining low-dose glucocorticoids with rituximab in IRNS treatment. This prospective, single-center cohort study enrolled 60 patients who were diagnosed with refractory IRNS with minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS) and treated at First Affiliated Hospital of Sun Yat-sen University. All patients received a treatment regimen consisting of rituximab (375 mg/m2/week × 4) and low-dose glucocorticoids. 46 complete remissions and 4 partial remissions were observed within 6 months of treatment. Within 12 months of treatment, 48 patients achieved complete remission, and 4 achieved partial remission. The complete remission rate for steroid-dependent/frequently relapsing nephrotic syndrome was significantly higher than that for steroid-resistant nephrotic syndrome (88.24% vs. 33.33%, p < .01). Following up for 12 months, 16 patients relapsed, accounting for 30.76% of the total, with a mean time to relapse of 10.97 months. Compared with baseline data, 24-hour urine protein quantification, total cholesterol and triglycerides significantly decreased, while serum albumin, globulin and IgG significantly increased at 12 months after treatment. All follow-ups were without serious adverse events. Twenty-four patients experienced infusion-related adverse reactions, which could be relieved by slowing down the infusion rate or suspending the infusion. Nine patients experienced infection-related adverse reactions; six of them were relieved with antibiotic treatment, and 3 patients were controlled by symptomatic treatment. Rituximab combined low-dose glucocorticoids therapy is effective and safe in idiopathic refractory nephrotic syndrome.
sj-pdf-14-jhs-10.1177_1753193420914762 - Supplemental material for BSSH Spring Meeting Abstracts
Creators: name: PHC Stirling
name: PJ Jenking
name: AD Duckworth
name: ND Clement
name: JE McEachan
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-14-jhs-10.1177_1753193420914762 for BSSH Spring Meeting Abstracts by in Journal of Hand Surgery (European Volume)
Additional file 5 of Expression and characterization of recombinant IL-1Ra in Aspergillus oryzae as a system
Creators: name: Mahmoudi Azar, Lena
name: Karaman, Elif
name: Beyaz, Burcu
name: Göktan, Işılay
name: Eyüpoğlu, Alp Ertunga
name: Kizilel, Seda
name: Erman, Batu
name: Gül, Ahmet
name: Uysal, Serdar
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 5: Figure S5. The raw chromatograms of size exclusion chromatography of serum mixed with Asp. IL -1Ra, serum mixed with E. coli IL -1Ra, Asp. IL-1Ra in the absence of serum, and serum; using a Superdex75 Increase 10/300 GL column.
MYTHS AND FACTS ABOUT THE EFFECTS OF NANO SELENIUM IN FARM ANIMALS – MINI-REVIEW
Creators: name: Pelyhe, Csilla
name: Mézes, Miklós
Publisher: name: European Chemical Bulletin
Year: 2013

description: Selenium plays important roles in antioxidant defence systems, prevents cell damage and is necessary for growth, fertility, and immune system in farm animals. Recently, nano-elemental Se has attracted wide spread attention due to its high bioavailability and low toxicity, because nanometer particulates exhibit novel characteristics, such as great specific surface area, high surface activity, a lot of surface active centres, high catalytic efficiency and strong adsorbing ability and over and above the character of low toxicity of Se0. Nano-Se had similar or higher bioavailability and much less toxicity in broiler chicken and goat as compared to selenite, while in contrast some studies suggested that nano-Se was more toxic than selenite to Medaka fish. Feeding trials have proven that nano-Se supplementation had a positive impact on the growth, feed efficiency of the rumen, fertility and on the antioxidant status of the animals. However, the bioactivity of nano-Se depends on the size, while heat treatment has measurable effect on the size, structure, and bioactivity of selenium nanoparticles. This suggests that if extensive heat exposure is unavoidable during the feed processing, smaller sized selenium nanoparticles should be used. A basic understanding of the absorption, distribution, and clearance and the whole metabolic pathways and mechanisms of nano-Se should be modelled and next to this the understand of negative effects should be investigated and demonstrated in parallel with the novel, promising characteristics as well before using it in common in the animal nutrition.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Additional file 1 of Development of UV-Chemometric techniques for resolving the overlapped spectra of aspirin, caffeine and orphenadrine citrate in their combined pharmaceutical dosage form
Creators: name: El-Adl, Sobhy M.
name: Mattar, Amr A.
name: El-Abassy, Omar M.
name: Sebaiy, Mahmoud M.
Publisher: name: figshare
Year: 2025
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology

description: Supplementary Material 1
Second transplantation after kidney graft loss in primary hyperoxaluria type 2: a pedigree study and mutation analysis
Creators: name: Peng, Yushi
name: Zheng, Yingchun
name: Xiong, Fu
name: Zhang, Mingming
name: Wang, Yuchen
name: Luo, Jia
name: Zeng, Wenli
name: Hui, Jialiang
name: Deng, Wenfeng
name: Xu, Jian
name: Miao, Yun
name: Xia, Renfei
name: Fang, Yiling
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Primary hyperoxaluria type 2 (PH2) is a rare disorder caused by GRHPR mutations. Research on the mutation spectrum and pedigree of PH2 helps in comprehending its pathogenesis and clinical outcomes, guiding clinical diagnosis and treatment. We report a case of PH2 with a three-generational pedigree. The GRHPR genotypes of the family members were confirmed by Sanger sequencing. Urine and blood samples were collected for biochemical analysis. Computational analysis was performed to assess the pathogenicity of the mutations. Cellular experiments based on site-directed mutagenesis were conducted to confirm the effect of mutations on GRHPR expression, activity, and subcellular localization. The proband underwent her first kidney transplantation in 2015, and experienced recurrent urinary tract infections and urolithiasis postoperatively. Graft failure occurred in 2018. Whole exome sequencing identified compound heterozygous GRHPR mutations p.G160E/p.P203Rfs*7. The patient underwent a second kidney transplantation in 2019 and maintained good graft function with urine dilution measures. Notably, her brother and sister carried the same mutations; however, only the proband progressed to renal failure. Computational analysis suggested that p.G160E reduced the affinity of GRHPR for coenzymes. Cellular experiments indicated that p.G160E reduced GRHPR activity (p < 0.001), whereas p.P203Rfs*7 not only suppressed expression (p < 0.001) and reduced activity (p < 0.001), but also facilitated protein aggregation. Based on our results, the variant p.G160E was classified as ‘pathogenic’ according to ACMG guidelines. Our findings suggest that treatment strategies for the long-term prevention of oxalate nephropathy should be developed for patients with PH2 receiving isolated kidney transplantation. Moreover, the pathogenicity of the compound heterozygous GRHPR mutations p.G160E/p.P203Rfs*7 was also validated.
Supplemental Material, Sleep.PD.COPPADIS.Manuscript.corrections - Sleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Disease
Creators: name: Santos-García, Diego
name: Castro, E. Suárez
name: de Deus Fonticoba, T.
name: Panceiras, M. J. Feal
name: Enriquez, J. G. Muñoz
name: González, J. M. Paz
name: Bartolomé, C. Cores
name: Planellas, L. L.
name: Caldentey, J. García
name: Caballol, N.
name: Legarda, I.
name: López, I. Cabo
name: Manzanares, L. López
name: Rivera, M. A. Ávila
name: Catalán, M. J.
name: Nogueira, V.
name: Borrué, C.
name: Sauco, M. Álvarez
name: Vela, L.
name: Cubo, E.
name: Castrillo, J. C. Martínez
name: Alonso, P. Sánchez
name: Losada, M. G. Alonso
name: Ariztegui, N. López
name: Gastón, M. I.
name: Kulisevsky, J.
name: Pagonabarraga, J.
name: Seijo, M.
name: Martínez, J. Ruíz
name: Valero, C.
name: Kurtis, M.
name: Ardura, J. González
name: Prieto, C.
name: Mir, P.
name: Martinez-Martin, P.
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 110308 Geriatrics and Gerontology
subject: FOS: Clinical medicine
subject: 110904 Neurology and Neuromuscular Diseases
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental Material, Sleep.PD.COPPADIS.Manuscript.corrections for Sleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Disease by Diego Santos-García, E. Suárez Castro, T. de Deus Fonticoba, M. J. Feal Panceiras, J. G. Muñoz Enriquez, J. M. Paz González, C. Cores Bartolomé, L. L. Planellas, J. García Caldentey, N. Caballol, I. Legarda, I. Cabo López, L. López Manzanares, M. A. Ávila Rivera, M. J. Catalán, V. Nogueira, C. Borrué, M. Álvarez Sauco, L. Vela, E. Cubo, J. C. Martínez Castrillo, P. Sánchez Alonso, M. G. Alonso Losada, N. López Ariztegui, M. I. Gastón, J. Kulisevsky, J. Pagonabarraga, M. Seijo, J. Ruíz Martínez, C. Valero, M. Kurtis, J. González Ardura, C. Prieto, P. Mir, P. Martinez-Martin and on behalf of the COPPADIS Study Group in Journal of Geriatric Psychiatry and Neurology
PHYSICOCHEMICAL ASSESSMENT OF WATER POLLUTANTS DUE TO THE SHIP BREAKING ACTIVITIES AND ITS IMPACT ON THE COASTAL ENVIRONMENT OF CHITTAGONG - BANGLADESH
Creators: name: Islam, M. Nazrul
name: Hossain, M. Akram
name: Ahmed, M. Jamaluddin
Publisher: name: European Chemical Bulletin
Year: 2013

description: The present research work deals with the assessment of water pollution due to Shipbreaking activities and its impact on the coastal zone of Chittagong, Bangladesh. In order to study the different physicochemical parameters, water samples from thirty Ship-breaking yards were collected and analyzed during the hydrological year 2011-2012. Collected water samples were analyzed for the following parameters using the procedure outlined in the standard methods: pH: 6.79 -8.22, EC: 25150-32500 µS cm-1, TDS: 9370-17740 mg L-1, TSS: 512-724 mg L-1, %NaCl: 30.21-60.8, DO: 3.01-6.89 mg L-1, BOD: 0.51 -3.17 mg L-1, COD: 178-338 mg L-1, acidity: 5.40 -9.02 mg L-1, alkalinity: 229.47 -310.19 mg L-1, total hardness: 750-1100 mg L-1, chloride: 10138.70  -21535.87 mg L-1, sulfate: 540.12 -608.64 mg L-1, phosphate: 1.062 -2.177 mg L-1, nitrite: 0.005 -0.030 mg L-1, nitrate: 0.256 -0.781 mg L-1, cadmium: 0.020 -0.039 mg L-1, chromium: 0.035 -0.790 mg L-1,  cobalt: 0.018 -0.055 mg L-1, copper: 0.023 -0.845 mg L-1, iron: 19.025-33.40 mg L-1, lead: 0.015 -0.043 mg L-1, manganese: 1.21 -2.648 mg L-1, nickel: 0.005 -0.049 mg L-1, silver: 0.021 -0.074 mg L-1, zinc: 0.097 -0.870 mg L-1.The laboratory findings were compared with the recommended values set by Department of Environment(DoE), and standard calculated on the BSTI and WHO value. Some parameters recorded as higher value compare to the international permissible limits in water. The study reveals that pollutants due to Ship-breaking are highly toxic in nature. This affects not only the aquatic environment and human beings of the surroundings but also poses a serious threat to ground and surface water resources of the adjoining areas and the coastal environment of Chittagong region. Also it is indicated that the water of ship breaking yards are continuously polluting the Bay of Bengals and the rivers of Chittagong, especially the water of Karnafuli River is being polluted greatly. The polluted water of the Karnafuli River may affect the biodiversity of the Halda River. Though Ship-breaking has earned a good reputation for being a profitable industry in developing countries it could be said that, the ship breaking operation involves serious environmental and human health hazards. It is one of the manmade hazards in the coastal region of Bangladesh.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Evaluation of DNA damage by the wastewater of Marrakech
Creators: name: Mokhtar, Chaik
name: Sana1, El Fadeli
name: Azeddine, Sedki
name: Nadra, Lekouch
Publisher: name: European Chemical Bulletin
Year: 2013

description: The present study was aimed to integrate genotoxicity test with routine toxicity test in 28 days repeated dose oral toxicity of Marrakesh’s wastewater in mice. Wastewater was administered at the dose of 25%, 50% and 75% per oral repeatedly for 28 days in mice. The endpoints of evaluation for routine toxicity testing included body weight (BW), organ weight (OW), food intake (FI), water intake (WI), hematology (HE) and histology (HI), while for the genotoxicity testing micronucleus (MN) and chromosomal aberration (CA) assay were used. The body weight (BW) significantly decreased at the highest dose of wastewater treatment as compared to the control group. Histological data (HI) revealed morphological alterations in the liver and lung cells at the highest dose of wastewater treatment. Micronucleus (MN) assay results indicated that the highest dose of wastewater led to a significant increase as compared to the control group. Chromosomal aberration (CA) assay results indicate significant DNA damage in different organs induced by wastewater as compared to the control group. Integration of a genotoxicity test with routine toxicity test would reduce the cost of additional animals and test items, while also providing further information at an early stage of product development
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Corrosion resistance of nanoparticle - incorporated nano coatings
Creators: name: Rathish, R. Joseph
name: Dorothy, R.
name: Joany, R. M.
name: Pandiarajan, M.
name: Rajendran, Susai
Publisher: name: European Chemical Bulletin
Year: 2013

description: Nano coatings are materials that are produced by shrinking the material at the molecular level to form a denser product.  Nano coatings have several advantages such as better surface appearance, good chemical resistance, better thermal and electrical conductivity and better corrosion resistance.  Incorporation of nanoparticles enhance the corrosion resistance of zeolite coatings, epoxy coatings and antimicrobial coatings.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Supplemental Material, sj-docx-1-ahp-10.1177_0890117120964144 - Foods for Health: An Integrated Social Medical Approach to Food Insecurity Among Patients With Diabetes
Creators: name: Blitstein, Jonathan L.
name: Lazar, Danielle
name: Gregory, Kathleen
name: McLoughlin, Colleen
name: Rosul, Linda
name: Rains, Caroline
name: Hellman, Talya
name: Leruth, Chelsey
name: Mejia, Jairo
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: Supplemental Material, sj-docx-1-ahp-10.1177_0890117120964144 for Foods for Health: An Integrated Social Medical Approach to Food Insecurity Among Patients With Diabetes by Jonathan L. Blitstein, Danielle Lazar, Kathleen Gregory, Colleen McLoughlin, Linda Rosul, Caroline Rains, Talya Hellman, Chelsey Leruth and Jairo Mejia in American Journal of Health Promotion
PHYSICOCHEMICAL ASSESSMENT OF SOIL POLLUTANTS DUE TO THE SHIP BREAKING ACTIVITIES AND ITS IMPACT ON THE COASTAL ZONE OF CHITTAGONG, BANGLADESH
Creators: name: Ahmed, M. Jamaluddin
name: Uddin, M. Nasir
name: Islam, M. Nazrul
name: Islam, M. Shahidul
name: Abdullah, M.
Publisher: name: European Chemical Bulletin
Year: 2013

description: The physicochemical assessment study was carried out to assess the soil quality in Ship-breaking yards of Chittagong region, Bangladesh. In order to study the different physicochemical parameters, soil samples from thirty Ship-breaking yards were collected and analyzed during the period 2011-2012. Collected soil samples were analyzed for the following parameters: pH, EC, soil salinity, nitrogen, potassium, chloride, phosphate, nitrate, nitrite, cadmium, chromium, arsenic, cobalt, copper, iron, lead, manganese, nickel, silver and zinc using the procedure outlined in the standard methods. The laboratory findings were compared with the recommended values set by the control area and standard calculated on the World Scale. The ranges of different physicochemical parameters obtained are as follows: pH: 4.17-6.92, EC: 1722-5600 µS cm-1, soil salinity: 16651.7-54152,  N: 115-1205 mg kg-1, K: 693.75-812.45 mg kg-1, chloride: 1900-7500 mg kg-1, phosphate: 8.36-34.84 mg kg-1, nitrite: 0.03-8.41 mg kg-1, nitrate: 0-74.05 mg kg-1, iron: 1250-10057 mg kg-1, manganese: 0-158.90 mg kg-1, chromium: 0.6-65.2 mg kg-1, cobalt: 5.75-24.45 mg kg-1, nickel: 16.30-162.2 mg kg-1, copper: 0-295.65 mg kg-1, zinc: 33.25-305.10 mg kg-1, silver: 4.60-132.45 mg kg-1, cadmium: 0.55-3.95 mg kg-1, lead: 0-137.05 mg kg-1, Arsenic: 0.0152-0.9505 mg kg-1.

Soil nutrients like N, K were found in the level below that of the control area and standard calculated on the World Scale. Trace and heavy metals like Ag, As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn were found very much higher than the control area and standard values set by World Scale. The anion like nitrate, nitrite, phosphate for which no standard values are recommended by World Scale are also not in good conditions and the concentration of chloride was very higher than the control area and the standard. From Pearson Correlation program, significant positive and negative correlations were found for different parameters. These assessment data indicated that the soil of Ship-breaking yards in Chittagong region are highly polluted which are continuously polluting the Coastal Zone, sea and  the rivers of Chittagong, especially the water of Karnafuli River is being polluted greatly. The polluted water of the Karnafuli River may affect the biodiversity of the Halda River.

Results from this study show that discharges from the broken Ships are highly toxic in nature. This affects not only the soil, aquatic environment and human beings of the surroundings but also poses a serious threat to ground and surface water resources of the adjoining areas and coastal zone of Chittagong, Bangladesh
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
BIOREMEDIATION OF CADMIUM(II) FROM AQUEOUS SOLUTION USING AGRICULTURAL WASTE: ZEA MAIZE LEAVES
Creators: name: Nadeem, Uzma
Publisher: name: European Chemical Bulletin
Year: 2013

description: In the present study, agricultural waste Zea maize leaves powder (MLP) was used for the removal of cadmium(II) from the aqueous solutions. The adsorption characteristics of maize leaf as a function of pH (2-7), adsorbent dose (0.2-0.5 g), temperature (20-30oC), contact time (0-120 min) and initial metal concentration (1-15 mg L-1) were studied. The biosorption of cadmium(II) on MLP was dependent on pH, adsorbent dose, temperature, contact time and initial metal concentration .The experimental results were analyzed in terms of Langmuir and Freundlich isotherm models. The Fourier Transform Infrared (FTIR) measurements reveal that the presence of hydroxyl, amino and carboxylic functional groups on the surface of MLP which provide the major biosorption sites for the metal binding. The results obtained could be useful for the application of agricultural wastes for heavy metal removal from the industrial waste water.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Additional file 1 of Lateral-flow device for the diagnosis of invasive aspergillosis: a systematic review and diagnostic meta-analysis
Creators: name: Fan, Yuqing
name: Shang, Xue
name: Wang, Yan
name: zhang, Yinghua
name: Li, Xiuxia
name: Yang, Kehu
name: Lv, Haidi
name: Guo, Kangle
Publisher: name: figshare
Year: 2025
Subjects: subject: Space Science
subject: Medicine
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Computational Biology

description: Supplementary Material 1
Two new chemical constituents from the aerial parts of Tripterygium wilfordii
Creators: name: Zhang, Xia
name: Huang, Lei
name: Tang, Yu-Jun
name: Hu, Ya-Lin
name: Xu, Wei
name: Li, Hong-Yu
name: Zhang, Yu-Bo
name: Zhang, Xiao-Qi
name: Zhou, Guang-Xiong
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biochemistry
Pharmacology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Virology

description: Tripterygium wilfordii has been historically employed as a conventional botanical insecticide and a plant of medicinal significance. A new dihydroagarofuran sesquiterpene (1) and a new acyclic compound (2), along with seven known compounds (3–9), have been isolated from the aerial parts of Tripterygium wilfordii. The identification of the structures of novel compounds were accomplished through comprehensive spectroscopic analyses, encompassing HRESIMS, NMR, UV, IR, and a comparative analysis with spectroscopic data from compounds previously characterised. In in-vitro bioassay, compound 8 exhibited significant inhibitory activity for NO release in LPS-induced RAW 264.7 cells, with an IC50 value of 15.7 μM.
Additional file 1 of What moves patients to participate in prehabilitation before major surgery? A mixed methods systematic review
Creators: name: van der Velde, Miriam
name: van der Leeden, Marike
name: Geleijn, Edwin
name: Veenhof, Cindy
name: Valkenet, Karin
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Science Policy
Mental Health

description: Additional file 1: Search strategy per database
Complete System Design - Public Version
Creators: name: Grefen, Paul
name: Vanderfeesten, Irene
name: Boultadakis, George
Publisher: name: Zenodo
Year: 2016
Subjects: subject: System Design
subject: Architecture
subject: FOS: Civil engineering

description: This document presents the complete system design of the HORSE project, concentrating on the logical architecture (as defined in the Kruchten 4+1 view framework) and providing a separation of concerns into software, data, process, organization and platform aspects (as defined in the Updated Truyens 5 aspect framework). The system design is based on the work in the HORSE requirements analysis task. Explicit confrontations with the HORSE system requirements specification are included.
Impaired sensitivity to thyroid hormones is associated with all-cause and cause-specific mortality among chronic kidney disease patients: results from National Health and Nutrition Examination Survey (NHANES) 2007–2012
Creators: name: Liu, Chan
name: Zhu, Xiaoxiao
name: Wang, Dingding
name: Huang, Naya
name: Chen, Wei
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Resistance to thyroid hormone shows underlying mechanical link with chronic kidney disease (CKD) and is prevalent in CKD population. However, whether it attributes to mortality risk among CKD population is unknown. This study aimed to examine the association of thyroid hormone resistance (THR) with all-cause and cause-specific mortality among CKD individuals. This study extracted CKD population from the National Health and Nutrition Examination Survey (NHANES) 2007–2012. Death outcomes were ascertained by linkage to National Death Index records through 31 December 2019. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence interval (CI) for mortality from all causes, cardiovascular disease (CVD). A total of 1,634 adults with CKD were included in the cohort, in which 663 deaths were recorded during an average follow-up of 8.72 years. After multivariate adjustment, resistance to thyroid hormone was significantly associated with higher all-cause and CVD mortality. There was an 18% and 31% increase in risks of all-cause and CVD mortality per-standard deviation (SD) increment in Parametric Thyroid Feedback Quantile-based Index (PTFQI) respectively. When PTFQI was analyzed as categorical variable (classified according to PTFQI percentiles), after adjusted for potential confounders and taking PTFQI ≤ P5 as reference, the HRs and 95% CIs in category with PTFQI > P95 for all-cause mortality and CVD mortality were 2.12 [1.10, 4.09] (p for trend 0.026) and 5.14 [1.81, 14.60] for (p for trend 0.018), respectively. Resistance to thyroid hormone, centered on variations in the typical pituitary response to thyroid hormones, may independently correlate with all-cause and CVD mortality in CKD patients.
Additional file 1 of A comprehensive integration of data on the association of ITPKC polymorphisms with susceptibility to Kawasaki disease: a meta-analysis
Creators: name: Habibi, Atefeh
name: Talebi, Hanieh
name: Bahrami, Reza
name: Golshan-Tafti, Mohammad
name: Shahbazi, Amirhossein
name: Dastgheib, Seyed Alireza
name: Tahooni, Azadeh
name: Vafapour, Maryam
name: Rashnavadi, Heewa
name: Pourkazemi, Melina
name: Yeganegi, Maryam
name: Sheikhpour, Elnaz
name: Neamatzadeh, Hossein
Publisher: name: figshare
Year: 2025
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
title: German Version of the Extended DCA-Transparency Scale
Creators: name: Hossiep, C. R.
name: Märtins, J.
name: Schewe, G.
Publisher: name: ZIS - GESIS Leibniz Institute for the Social Sciences
Year: 2022
Subjects: subject: information quality
subject: disclosure
subject: clarity
subject: accuracy
subject: timeliness
subject: relevance

description: Transparency describes the quality of information perceived by an information recipient. The con-struct is increasingly gaining attention in the scientific and practical context. The dimensions Disclo-sure, Clarity and Accuracy as well as Timeliness and Relevance form individuals’ transparency per-ceptions. Based on these dimensions, a German questionnaire with 20 items with four items for each dimension was presented. This five-dimensional scale shows high internal consistency (> .88) and indicators for objectivity, reliability, and validity (content, criterion, and construct validity) are availa-ble. The validation study indicates that transparency dimensions differ with regard to their relationship to trustworthiness, trust and job satisfaction. In addition, first investigations show that the scale can be applied in contexts outside the organization.
description: ZIS - The Collection of Items and Scales for the Social Sciences
Supplemental Material, Appendix - A bibliometric analysis of multimorbidity from 2005 to 2019
Creators: name: Ahmed, Mohamed Ali Ag
name: Almirall, José
name: Ngangue, Patrice
name: Marie-Eve Poitras
name: Fortin, Martin
Publisher: name: SAGE Journals
Year: 2020
Subjects: Medicine

description: Supplemental Material, Appendix for A bibliometric analysis of multimorbidity from 2005 to 2019 by Mohamed Ali Ag Ahmed, José Almirall, Patrice Ngangue, Marie-Eve Poitras and Martin Fortin in Journal of Comorbidity
Additional file 3 of An increased risk of pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema: a meta-analysis
Creators: name: Ni, Hangqi
name: Wei, Yuying
name: Yang, Liuqing
name: Wang, Qing
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Cancer

description: Additional file 3: Supplementary File 3. Flow diagram for the analysis of the effect of PH on survival in CPFE patients.
Trotta_Supplemental_Material – Supplemental material for Interpretation Bias in Paranoia: A Systematic Review and Meta-Analysis
Creators: name: Trotta, Antonella
name: Jungwoo Kang
name: Stahl, Daniel
name: Yiend, Jenny
Publisher: name: SAGE Journals
Year: 2020
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, Trotta_Supplemental_Material for Interpretation Bias in Paranoia: A Systematic Review and Meta-Analysis by Antonella Trotta, Jungwoo Kang, Daniel Stahl and Jenny Yiend in Clinical Psychological Science
AN EFFICIENT ECOFRIENDLY PROTOCOL FOR THE SYNTHESIS AND BIOLOGICAL EVALUATION OF SPIRO[ACENAPHTHYLENE-1,2′-PYRROLIDINE] DERIVATIVES AS POTENT ANTI-INFECTIVE AGENTS
Creators: name: Dandia, Anshu
name: Kumari, Sukhbeer
Publisher: name: European Chemical Bulletin
Year: 2013

description: A series of spiro[acenaphthylene-1,2′-pyrrolidine] derivatives (4a-j) were synthesized by highly efficient one-pot three-component reaction of acenaphthenequinone, sarcosine and Knoevenagel adduct in 2,2,2-trifluoroethanol as a reusable green solvent. All the synthesized compounds were screened for their ‘in vitro’ antimalarial activity against the growth of Plasmodium falciparum, the malaria causing parasite. Some of them showed antimalarial activity with IC50 values as low as 0.003 and 0.005 mg/mL. The compounds were evaluated for their antibacterial activity against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Streptococcus pyogenes and for antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus clavatus. Some of the compounds exhibited excellent antibacterial activity and compounds 4c and 4e demonstrated significant antifungal activities than the standard drugs.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Protective effect of ascorbic acid against renal injury induced by 3-chloropropane-1,2-diol-dipalmitate in rats
Creators: name: Wei, Tao
name: Liu, Bohan
name: Chen, Yi
name: Li, Chang
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Marine Biology

description: 3-monochloropropane-1,2-diol esters (3-MCPDE) are a group of contaminants which are mainly formed during heat processing of edible oil and fat-based foods. The kidney is the primary target organ for the toxic effects of 3-MCPDE. 3-MCPD-di-palmitate exists in a variety of oils and fats, and is the most common and relatively high proportion of 3-MCPDE. In this study, we investigated the protective effect of ascorbic acid on 3-MCPD-di-palmitate-induced renal injury in rats. Thirty 8-week-old male Sprague-Dawley rats were randomly divided into 5 groups, namely control, 3-MCPD-di-palmitate (240 mg/kg·bw), 3-MCPD-di-palmitate (240 mg/kg·bw) + ascorbic acid (100 mg/kg·bw), 3-MCPD-di-palmitate (240 mg/kg·bw) + ascorbic acid (200 mg/kg·bw) and 3-MCPD-di-palmitate (240 mg/kg·bw) + ascorbic acid (500 mg/kg·bw). These treatments were administered via gavage for a duration of 4 weeks. The effects of ascorbic acid on 3-MCPDE-induced kidney injury in rats were investigated by evaluating the kidney index, renal function (BUN, CRE), renal histopathology, oxidative stress markers (ROS, GSH, MDA, and T-AOC), DNA oxidation marker (8-OHdG), and activities of Caspase 3 and 9. The results showed that the exposure to 3-MCPDE significantly increased the kidney index, BUN and CRE levels, ROS and MDA levels, 8-OHdG levels, and activities of Caspase 3 and 9, while decreasing GSH and T-AOC. The combined treatment with 3-MCPDE and ascorbic acid can effectively restore the aforementioned parameters. The present study concluded that ascorbic acid effectively attenuates the renal apoptosis and oxidative homeostasis induced by 3-MCPDE uptake thereby intervening in renal injury.
Spectrophotometric determination of ampicillin and cloxacillin in pure and fixed dosage forms through charge transfer complexation
Creators: name: Ezeanokette, Chigozie C
name: Ngwoke, Kenneth Gerald
name: Okoye, Festus Basden
name: Osadebe, Patience A
Publisher: name: European Chemical Bulletin
Year: 2013

description: Simple, precise and accurate visible spectrophotometric procedure was developed for the quantitative determination of two antibacterials, ampicillin and cloxacillin in a fixed dose combination. The method exploits the formation of charge transfer complexes between the antibacterials and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) to determine the components of the drugs in a dosage form. The effect of different variables on the development and stability of the complexes were studied and optimized. Beer’s law was obeyed. The method was successfully applied to the determination of the target analytes in different brands of the fixed dose combination.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Additional file 2 of An increased risk of pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema: a meta-analysis
Creators: name: Ni, Hangqi
name: Wei, Yuying
name: Yang, Liuqing
name: Wang, Qing
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biological Sciences not elsewhere classified
Cancer

description: Additional file 2: Supplementary Table 2. Selecting criterion for the analysis of the effect of PH on survival in CPFE patients.
Additional file 1 of Strengthening local government policies to address health inequities: perspectives from Australian local government stakeholders
Creators: name: Schultz, Sally
name: Zorbas, Christina
name: Peeters, Anna
name: Yoong, Serene
name: Backholer, Kathryn
Publisher: name: figshare
Year: 2024
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplementary Material 1
Preoperative leptin levels were associated with postoperative acute kidney injury in patients with acute type A aortic dissection
Creators: name: Cai, Meiling
name: Jiang, Fei
name: Peng, Yanchun
name: Li, Sailan
name: Xie, Yuling
name: Chen, Liangwan
name: Lin, Yanjuan
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Acute kidney injury (AKI) is a common surgical complication of acute type A aortic dissection (AAAD) and strongly associated with an unfavorable prognosis. Although elevated leptin levels have been identified as a potential risk factor for chronic kidney disease in middle-aged and elderly individuals, their association with AKI following AAAD surgery remains unknown. This study investigated the association between preoperative leptin levels and postoperative AKI in patients with AAAD. This study included 159 patients with AAAD at Fujian Heart Medical Center. The Kidney Disease: Improving Global Outcomes standards were used to define and classify AKI. The receiver operating characteristic (ROC) curves were used to assess the ability of leptin levels to predict AKI. Binary logistic regression analysis was used to study the association between leptin level and AKI. The incidence of AKI was 33.96%. Leptin levels in the AKI group and stage 1, 2, and 3 AKI groups were higher than those in the non-AKI group (p < 0.05). Multivariate analysis revealed that elevated leptin levels were an independent risk factor for AKI (p < 0.001). ROC analysis of leptin detection for AKI showed an area under the curve of 0.71. The risk of AKI in the high-level group (leptin levels ≥3.62 ng/mL) was 3.87 times to the low-level group (leptin levels < 3.62 ng/mL). Elevated leptin levels are associated with AKI, and plasma leptin may serve as a potential early blood biomarker for AKI in patients with AAAD.
Additional file 1 of A practical illustration of spatial smoothing methods for disconnected regions with INLA: spatial survey on overweight and obesity in Malaysia
Creators: name: Mohamad, Maria Safura
name: Abdul Maulud, Khairul Nizam
name: Faes, Christel
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: Additional file 1: Posterior summary statistics of design-based prevalence estimates and model-based prevalence estimates of overweight, NHMS 2015, Malaysia.
Supplementary_Material_S1_xyz249921690d701 – Supplemental material for Assexon: Assembling Exon Using Gene Capture Data
Creators: name: Yuan, Hao
name: Atta, Calder
name: Tornabene, Luke
name: Li, Chenhong
Publisher: name: SAGE Journals
Year: 2019
Subjects: Cell Biology

description: Supplemental material, Supplementary_Material_S1_xyz249921690d701 for Assexon: Assembling Exon Using Gene Capture Data by Hao Yuan, Calder Atta, Luke Tornabene and Chenhong Li in Evolutionary Bioinformatics
ON THE MOLAR EXTINCTION COEFFICIENTS OF THE ELECTRONIC ABSORPTION SPECTRA OF C60 AND C70 FULLERENES RADICAL CATION
Creators: name: Cataldo, Franco
name: Iglesias-Groth, Susana
name: Hafez, Yaser
Publisher: name: European Chemical Bulletin
Year: 2013

description: Fullerene C60 and C70 were discovered in 2010 by means of infrared spectroscopy in a series of astrophysical objects like for example planetary and protoplanetary nebulae and reflection nebulae. These discoveries suggest that C60 and C70 must be widespread in the interstellar medium and may contribute as neutral species or as radical cation (C60+• and C70+•)  to the DIBs, the Diffuse Interstellar Bands which are attributed to the electronic transitions of molecules and radicals. In this paper are reported the electronic absorption spectra of both C60 and C70 and of their radical cations C60+• and C70+• together with the molar extinction coefficients of all the main absorption bands. All these experimental data are key tools for the qualitative and quantitative search and recognition of these molecules and radicals in space using electronic transitions rather than infrared transition. Furthermore, the electronic absorption bands and molar extinction coefficients of hydrogenated and perdeuterated fullerenes (known as fulleranes) and higher fullerenes are reported.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
CORRELATION ANALYSIS OF REACTIVITY IN THE OXIDATION OF ORGANIC SULFIDES BY BENZYLTRIETHYLAMMONIUM CHLOROCHROMATE: A KINETIC APPROACH
Creators: name: Sharma, Pradeep
Publisher: name: European Chemical Bulletin
Year: 2013

description: The oxidation of some organic sulfides by benzyltriethylammonium chlorochromate (BTEACC) resulted in the formation of the corresponding sulfoxides. The reaction is first order with respect to both BTEACC and the sulfide. The reaction is catalysed by toluene-p-sulfonic acid (TsOH). The oxidation was studied in nineteen different organic solvents. An analysis of the solvent effect by Swain's equation showed that the both cation‑ and anion‑solvating powers of the solvents play important roles. The correlation analyses of the rate of oxidation of thirty four sulfides were performed in terms of various single and multiparametric equations. For the aryl methyl sulfides, the best correlation is obtained with Charton's LDR and LDRS equations. The oxidation of alkyl phenyl sulfides exhibited a very good correlation in terms of Pavelich-Taft equation. The polar reaction constants are negative indicating an electron‑deficient sulfur centre in the rate‑determining step.  A mechanism involving formation of a sulphenium cation intermediate in the slow step has been proposed.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
kleinSelle_OpenPracticesDisclosure_rev – Supplemental material for Hide or Seek? Physiological Responses Reflect Both the Decision and the Attempt to Conceal Information
Creators: name: Selle, Nathalie Klein
name: Agari, Naama
name: Ben-Shakhar, Gershon
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 110904 Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: Neuroscience

description: Supplemental material, kleinSelle_OpenPracticesDisclosure_rev for Hide or Seek? Physiological Responses Reflect Both the Decision and the Attempt to Conceal Information by Nathalie klein Selle, Naama Agari and Gershon Ben-Shakhar in Psychological Science
Supplemental Material, Appendix_A - Discretion and Disparity under Sentencing Guidelines Revisited: The Interrelationship between Structured Sentencing Alternatives and Guideline Decision-making
Creators: name: Painter-Davis, Noah
name: Ulmer, Jeffery T.
Publisher: name: SAGE Journals
Year: 2019
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental Material, Appendix_A for Discretion and Disparity under Sentencing Guidelines Revisited: The Interrelationship between Structured Sentencing Alternatives and Guideline Decision-making by Noah Painter-Davis and Jeffery T. Ulmer in Journal of Research in Crime and Delinquency
PREPARATION AND PHOTOCATALYTIC PROPERTIES OF    Fe3+-DOPED TiO2 NANOPARTICLES
Creators: name: Zhou, Guoqiang
name: Wang, Wenying
name: Zheng, Baofeng
name: Li, Yang
Publisher: name: European Chemical Bulletin
Year: 2013

description: The Fe3+-doped TiO2 nanoparticles were synthesized by sol-gel method in an aqueous solution at a temperature of 160 °C. The effect of particle size, Fe3+-doping and dosage on the photocatalytic activity of the nanoparticles was investigated. The synthesized Fe3+-doped TiO2 nanoparticles were analyzed by field emission scanning electron microscopy, transmission electron microscope, powder X-ray diffraction and dynamic light scattering. The nanoparticles had irregular shapes, and the primary size of particles was  approximately 100 nm. Though the Fe3+-doping did not change the crystal structure of TiO2, but it had significant affect  on their photocatalytic properties. 0.5 % Fe3+-doped TiO2 had the best photocatalytic performance. The particle size of Fe3+-doped TiO2 samples also influenced its photocatalytic activity.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin
Identification of kidney-related medications using AI from self-captured pill images
Creators: name: Sheikh, Mohammad S.
name: Dreesman, Benjamin
name: Barreto, Erin F.
name: Thongprayoon, Charat
name: Miao, Jing
name: Suppadungsuk, Supawadee
name: Mao, Michael A.
name: Qureshi, Fawad
name: Pham, Justin H.
name: Craici, Iasmina M.
name: Kashani, Kianoush B.
name: Cheungpasitporn, Wisit
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Medicine
Neuroscience
Biotechnology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
Mental Health

description: ChatGPT, a state-of-the-art large language model, has shown potential in analyzing images and providing accurate information. This study aimed to explore ChatGPT-4 as a tool for identifying commonly prescribed nephrology medications across different versions and testing dates. 25 nephrology medications were obtained from an institutional pharmacy. High-quality images of each medication were captured using an iPhone 13 Pro Max and uploaded to ChatGPT-4 with the query, ‘What is this medication?’ The accuracy of ChatGPT-4’s responses was assessed for medication name, dosage, and imprint. The process was repeated after 2 weeks to evaluate consistency across different versions, including GPT-4, GPT-4 Legacy, and GPT-4.Ø. ChatGPT-4 correctly identified 22 out of 25 (88%) medications across all versions. However, it misidentified Hydrochlorothiazide, Nifedipine, and Spironolactone due to misreading imprints. For instance, Nifedipine ER 90 mg was mistaken for Metformin Hydrochloride ER 500 mg because ‘NF 06’ was misread as ‘NF 05’. Hydrochlorothiazide 50 mg was confused with the 25 mg version due to imprint errors, and Spironolactone 25 mg was misidentified as Naproxen Sodium or Diclofenac Sodium. Despite these errors, ChatGPT-4 showed 100% consistency when retested, correcting misidentifications after receiving feedback on the correct imprints. ChatGPT-4 shows strong potential in identifying nephrology medications from self-captured images, though challenges with difficult-to-read imprints remain. Providing feedback improved accuracy, suggesting ChatGPT-4 could be a valuable tool in digital health for medication identification. Future research should enhance the model’s ability to distinguish similar imprints and explore broader integration into digital health platforms.
Additional file 1 of Caenorhabditis monodelphis sp. n.: defining the stem morphology and genomics of the genus Caenorhabditis
Creators: name: Slos, Dieter
name: Sudhaus, Walter
name: Stevens, Lewis
name: Bert, Wim
name: Blaxter, Mark
Publisher: name: figshare
Year: 2025
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Nucleic acid isolation from Caenorhabditis monodelphis sp. n strain JU1677. (DOCX 13 kb)
COBALT DOPED ZNS NANOPARTICLES AS A RECYCLABLE CATALYST FOR AQUEOUS MEDIATED SYNTHESIS OF 2,4,5-TRIARYL-1H-IMIDAZOLES UNDER ULTRASONIC IRRADIATION
Creators: name: Dandia, Anshu
name: Parewa, Vijay
name: Sharma, Amit
name: Rathore, Kuldeep S.
Publisher: name: European Chemical Bulletin
Year: 2013

description: Facile and efficient synthesis of 2,4,5-triarylimidazoles has been achieved by employing three-component one-pot reaction using aromatic aldehydes, benzil and NH4OAc  in the presence of  Co doped ZnS nanoparticles in water under ultrasonic irradiation. Doping of Co promotes the activity and selectivity of ZnS nanoparticles indicated by high TOF value. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst.
description: European Chemical Bulletin, Vol 2, No 12 (2013): European Chemical Bulletin