cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Roper Commercial # 128: Physicians Opinions of Psychotherapeutic Drugs
Creators: name: Organization, The Roper
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Amount of prosperity (1); confidence in leaders (2); management concerns (2); domestic companies overseas (3); underdeveloped countries (3); amount of imports (1); import restrictions (4); most interesting article (1); best company for employees (1); future prospects of various industries (8); government inspections (7); amount of profit (3); best research oil companies (1); favorability of various companies (3); Standard Oil companies (1); evaluation of various business practices (14); company heard most about (1); personal investments in companies (3); company-government cooperation (2); most troublesome companies (2); companies involved in multiple branches (18); gasoline brand names (3); stock ownership (1); investment preferences (5); oil company stock ownership (7); automobile ownership (1); preferred gasoline brand (5); company descriptions (30).
Evolution and Nucleosynthesis of Very Massive Stars
Creators: name: Hirschi, Raphael
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: In this chapter, after a brief introduction and overview of stellar evolution, we discuss the evolution and nucleosynthesis of very massive stars (VMS: M>100 solar masses) in the context of recent stellar evolution model calculations. This chapter covers the following aspects: general properties, evolution of surface properties, late central evolution, and nucleosynthesis including their dependence on metallicity, mass loss and rotation. Since very massive stars have very large convective cores during the main-sequence phase, their evolution is not so much affected by rotational mixing, but more by mass loss through stellar winds. Their evolution is never far from a homogeneous evolution even without rotational mixing. All VMS at metallicities close to solar end their life as WC(-WO) type Wolf-Rayet stars. Due to very important mass loss through stellar winds, these stars may have luminosities during the advanced phases of their evolution similar to stars with initial masses between 60 and 120 solar masses. A distinctive feature which may be used to disentangle Wolf-Rayet stars originating from VMS from those originating from lower initial masses is the enhanced abundances of neon and magnesium at the surface of WC stars. At solar metallicity, mass loss is so strong that even if a star is born with several hundred solar masses, it will end its life with less than 50 solar masses (using current mass loss prescriptions). At the metallicity of the LMC and lower, on the other hand, mass loss is weaker and might enable star to undergo pair-instability supernovae.
description: 42 pages, 20 figures, Book Chapter in "Very Massive Stars in the Local Universe", Springer, Ed. Jorick S. Vink
Roper Commercial # 129: Beliefs and Attitudes of College Seniors, Freshmen, and Alumni (Males Only)
Creators: name: Organization, The Roper
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Future outlook (2); societal outlook (2); most important problems (3); individual effect (1); active social role (1); descriptions of American systems (4); system criticisms (8); student activity changes (2); college satisfaction (2); college activities (5); college cost (1); future salary (3); Presidential candidate preference (3); support enthusiasm (1); statements about various organizations (5); confidence in leaders (3); descriptions about various leaders (33); job aspects (10); best career fields (10); employee qualities (6); career choice (4); attractive job aspects (2); American business statements (10); nation's welfare (1); working for corporations (1); business recruiters (5); plans after school (1); military career (1); graduate school (1); future job (1); military service eligibility (2); avoiding service (1); most appealing future (2); concept of God (1); organized religion (1); drug sales (2); drug use (2); sex before marriage (1); sexual partners (1).
Newtonian analogue of Schwarzschild de-Sitter spacetime: Influence on the local kinematics in galaxies
Creators: name: Sarkar, Tamal
name: Ghosh, Shubhrangshu
name: Bhadra, Arunava
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The late time accelerated expansion of the Universe demands that even in local galactic-scales it is desirable to study astrophysical phenomena, particularly relativistic accretion related phenomena in massive galaxies or in galaxy mergers and the dynamics of the kiloparsecs-scale structure and beyond, in the local-galaxies in Schwarzschild-de Sitter (SDS) background, rather than in Schwarzschild or Newtonian paradigm. Owing to the complex and nonlinear character of the underlying magnetohydrodynamical equations in general relativistic (GR) regime, it is quite useful to have an Newtonian analogous potential containing all the important GR features that allows to treat the problem in Newtonian framework for study of accretion and its related processes. From the principle of conserved Hamiltonian of the test particle motion, here, a three dimensional Newtonian analogous potential has been obtained in spherical geometry corresponding to SDS/Schwarzschild anti-de Sitter (SADS) spacetime, that reproduces almost all of the GR features in its entirety with remarkable accuracy. The derived potential contains an explicit velocity dependent term of the test particle that renders an approximate relativistic modification of Newtonian like potential. The complete orbital dynamics around SDS geometry and the epicyclic frequency corresponding to SDS metric have been extensively studied in the Newtonian framework using the derived potential. Applying the derived analogous potential it is found that the current accepted value of $Λ\sim 10^{-56} \rm cm^{-2}$ moderately influences both sonic radius as well as Bondi accretion rate, especially for spherical accretion with smaller values of adiabatic constant and temperature, which might have interesting consequences on the stability of accretion disk in AGNs/radio galaxies.
description: 25 pages, 12 figures
Global survey of star clusters in the Milky Way III. 139 new open clusters at high Galactic latitudes
Creators: name: Schmeja, S.
name: Kharchenko, N. V.
name: Piskunov, A. E.
name: Röser, S.
name: Schilbach, E.
name: Froebrich, D.
name: Scholz, R. -D.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: An earlier analysis of the Milky Way Star Cluster (MWSC) catalogue revealed an apparent lack of old (> 1 Gyr) open clusters in the solar neighbourhood (< 1 kpc). To fill this gap we undertook a search for hitherto unknown star clusters, assuming that the missing old clusters reside at high Galactic latitudes |b|> 20°. We were looking for stellar density enhancements using a star count algorithm on the 2MASS point source catalogue. To increase the contrast between potential clusters and the field, we applied filters in colour-magnitude space according to typical colour-magnitude diagrams of nearby old open clusters. The subsequent comparison with lists of known objects allowed us to select thus far unknown cluster candidates. For verification they were processed with the standard pipeline used within the MWSC survey for computing cluster membership probabilities and for determining structural, kinematic, and astrophysical parameters. In total we discovered 782 density enhancements, 522 of which were classified as real objects. Among them 139 are new open clusters with ages 8.3 < log (t [yr]) < 9.7, distances d < 3 kpc, and distances from the Galactic plane 0.3 < Z < 1 kpc. This new sample has increased the total number of known high latitude open clusters by about 150%. Nevertheless, we still observe a lack of older nearby clusters up to 1 kpc from the Sun. This volume is expected to still contain about 60 unknown clusters that probably escaped our detection algorithm, which fails to detect sparse overdensities with large angular size.
description: 11 pages, 11 figures; accepted for publication in A&A
Characterization of the Fecal Microbiota Using High-Throughput Sequencing Reveals a Stable Microbial Community during Storage
Creators: name: Klaenhammer, Todd R.
name: Siddle, Jennica P.
name: Ringel, Yehuda
name: Carroll, Ian M.
name: Ringel-Kulka, Tamar
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The handling and treatment of biological samples is critical when characterizing the composition of the intestinal microbiota between different ecological niches or diseases. Specifically, exposure of fecal samples to room temperature or long term storage in deep freezing conditions may alter the composition of the microbiota. Thus, we stored fecal samples at room temperature and monitored the stability of the microbiota over twenty four hours. We also investigated the stability of the microbiota in fecal samples during a six month storage period at −80°C. As the stability of the fecal microbiota may be affected by intestinal disease, we analyzed two healthy controls and two patients with irritable bowel syndrome (IBS). We used high-throughput pyrosequencing of the 16S rRNA gene to characterize the microbiota in fecal samples stored at room temperature or −80°C at six and seven time points, respectively. The composition of microbial communities in IBS patients and healthy controls were determined and compared using the Quantitative Insights Into Microbial Ecology (QIIME) pipeline. The composition of the microbiota in fecal samples stored for different lengths of time at room temperature or −80°C clustered strongly based on the host each sample originated from. Our data demonstrates that fecal samples exposed to room or deep freezing temperatures for up to twenty four hours and six months, respectively, exhibit a microbial composition and diversity that shares more identity with its host of origin than any other sample.
Roper Reports 1982-06: Reagan Administration/Business/Consumerism
Creators: name: Organization, The Roper
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Interest in current events; support of, and attitude toward, Ronald Reagan; Reagan administration's attitude toward the poor and minorities; governmental priorities regarding inflation, peace between Israel and Arab nations, U.S./USSR relations, limiting nuclear weapons, individual privacy, consumer protection, advertising, race and poverty, crime and drugs, energy sources and use, national health insurance and unemployment; sympathies toward Israel and Arab nations; Falkland Islands conflict; position of various foreign countries toward U.S.; unemployment; large business corporations; small business companies; opinion of various large corporations; U.S. industry profits; inflation; investment capital in new industry and equipment; American business management; personal automobile data; foreign vs. American cars; consumer purchases; tax on oil imports; probability of future oil and gas shortages; cash vs. credit card purchasing of gasoline; government bans on consumer products; botulism; purchasing of various imports vs. U.S. made products; computer files on personal information higher education; bilingual (Spanish/English) classes in public schools; prayer in school; information sources; ownership or operation of typewriter, word processor, calculator, photocopier and/or computer equipment; political ideology; political activity.
Cooper approach to pair formation in a tight-binding model of La-based cuprate superconductors
Creators: name: Frahm, Klaus M.
name: Shepelyansky, Dima L.
Publisher: name: arXiv
Year: 2022
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We study numerically, in the framework of the Cooper approach from 1956, mechanisms of pair formation in a model of La-based cuprate superconductors with longer-ranged hopping parameters reported in the literature at different values of center of mass momentum. An efficient numerical method allows to study lattices with more than a million sites. We consider the cases of attractive Hubbard and d-wave type interactions and a repulsive Coulomb interaction. The approach based on a frozen Fermi sea leads to a complex structure of accessible relative momentum states which is very sensitive to the total pair momentum of static or mobile pairs. It is found that interactions with attraction of approximately half of an electronvolt give a satisfactory agreement with experimentally reported results for the critical superconducting temperature and its dependence on hole doping. Ground states exhibit d-wave symmetries for both attractive Hubbard and d-wave interactions which is essentially due to the particular Fermi surface structure and not entirely to an eventual d-wave symmetry of the interaction. We also find pair states created by Coulomb repulsion at excited energies above the Fermi energy and determine the different mechanisms of their formation. In particular, we identify such pairs in a region of negative mass at rather modest excitation energies which is due to a particular band structure.
description: 20 pages (16 figures) + 7 pages SupMat (17 figures); additional data/raw figures available at: https://www.quantware.ups-tlse.fr/QWLIB/electronpairsforhtc/
Perceptions of Socio-Political Change in South Africa (Coloureds, Indians and Whites): Phase I and Phase II, 1982
Creators: name: Provided By The South African Data Archive
Publisher: name: Roper Center for Public Opinion Research
Year: 2020

description: President's Council proposals (7); President's Council composition (1); representation of Coloured and Indian populations (3); political representation and participation of Blacks living outside the homelands (13); effects of implementing proposals (16); conservative reaction to proposal (4); improving living standards (2); most and least hurtful government measures (2); political equality (8); reactions to proposal decisions (3); consociational democracy (8); understanding of proposals (5); media coverage of proposals (6); relations, conflict among South Africa's different population groups (5); power sharing among different population groups (3); Prime Minister's guidelines for constitutional reform (7); mixed White, Coloured, and Indian Parliament and Cabinet (6); exclusion of Blacks from central government (7); name under which Coloured population should be represented (1); election participation (1); confidence in present Government (1); numerical ratios as formula for power sharing (10); negotiation with Government by community political leaders (1); special affairs of population group vs. common, joint interests (18); Presidential power (3); Group Areas Act (2); greatest threat to peace in South Africa (1); main source of information on Prime Minister's guidelines (1); Black majority government (7); territorial division of South Africa (6); adopting new national anthem (1); talking about politics with people (1); receptiveness to proposed new system of government (2); opinion of President's Council (1); understanding of Government's plans for division of political power (1); holding national convention to work out new system (1); holding referendum or general election before implementing government reform (1); opinion about proposed new Parliament (4); people from various religions and population groups as President (6); effects of Prime Minister's guidelines (5); conservative reaction to guidelines (3).
Fannie Mae National Housing Survey Monthly Key Indicators--November, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Fannie Mae National Housing Survey Monthly Key Indicators--December, 2011 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Fannie Mae National Housing Survey Monthly Key Indicators--January, 2012 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Comparison and Temporal Trends of Three Groups with Cryptococcosis: HIV-Infected, Solid Organ Transplant, and HIV-Negative/Non-Transplant
Creators: name: Perfect, John R.
name: Bratton, Emily W.
name: Weber, David J.
name: Juliano, Jonathan J.
name: Poole, Charles
name: Stürmer, Til
name: Lee, Michael S.
name: Chastain, Cody A.
name: El Husseini, Nada
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: BackgroundThe Infectious Disease Society of America (IDSA) 2010 Clinical Practice Guidelines for the management of cryptococcosis outlined three key populations at risk of disease: (1) HIV-infected, (2) transplant recipient, and (3) HIV-negative/non-transplant. However, direct comparisons of management, severity and outcomes of these groups have not been conducted.Methodology/Principal FindingsAnnual changes in frequency of cryptococcosis diagnoses, cryptococcosis-attributable mortality and mortality were captured. Differences examined between severe and non-severe disease within the context of the three groups included: demographics, symptoms, microbiology, clinical management and treatment. An average of nearly 15 patients per year presented at Duke University Medical Center (DUMC) with cryptococcosis. Out of 207 study patients, 86 (42%) were HIV-positive, 42 (20%) were transplant recipients, and 79 (38%) were HIV-negative/non-transplant. HIV-infected individuals had profound CD4 lymphocytopenia and a majority had elevated intracranial pressure. Transplant recipients commonly (38%) had renal dysfunction. Nearly one-quarter (24%) had their immunosuppressive regimens stopped or changed. The HIV-negative/non-transplant population reported longer duration of symptoms than HIV-positive or transplant recipients and 28% (22/79) had liver insufficiency or underlying hematological malignancies. HIV-positive and HIV-negative/non-transplant patients accounted for 89% of severe disease cryptococcosis-attributable deaths and 86% of all-cause mortality.Conclusions/SignificanceIn this single-center study, the frequency of cryptococcosis did not change in the last two decades, although the underlying case mix shifted (fewer HIV-positive cases, stable transplant cases, more cases with neither). Cryptococcosis had a relatively uniform and informed treatment strategy, but disease-attributable mortality was still common.
Das neue Blatt 17,1/3; 1886
Creators: name: (:Unav)
Publisher: name: Universitätsbibliothek der Ludwig-Maximilians-Universität München
Year: 1886

description: Mehrere Sprünge in Seitenzählung: 173-178, 206-223, 229-210, 222-229, 256 - drei ungezählte Seiten - 258, 480 - drei ungezählte Seiten - 482
Fannie Mae National Housing Survey Monthly Key Indicators--February, 2012 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Fannie Mae National Housing Survey Monthly Key Indicators--March, 2012 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Fannie Mae National Housing Survey Monthly Key Indicators--April, 2012 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Fannie Mae National Housing Survey Monthly Key Indicators--May, 2012 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Coronary Artery Remodeling in a Model of Left Ventricular Pressure Overload Is Influenced by Platelets and Inflammatory Cells
Creators: name: Caicedo, Jessica
name: Odetunde, Juliana
name: Abdel-Latif, Ahmed
name: Barrick, Cordelia J.
name: Klyachkin, Yuri M.
name: Mueller, Paul
name: Dong, Anping
name: Sutton, Alyssa Moore
name: Yang, Fanmuyi
name: Smyth, Susan S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Left ventricular hypertrophy (LVH) is usually accompanied by intensive interstitial and perivascular fibrosis, which may contribute to arrhythmogenic sudden cardiac death. The mechanisms underlying the development of cardiac fibrosis are incompletely understood. To investigate the role of perivascular inflammation in coronary artery remodeling and cardiac fibrosis during hypertrophic ventricular remodeling, we used a well-established mouse model of LVH (transverse aortic constriction [TAC]). Three days after pressure overload, macrophages and T lymphocytes accumulated around and along left coronary arteries in association with luminal platelet deposition. Consistent with these histological findings, cardiac expression of IL-10 was upregulated and in the systemic circulation, platelet white blood cell aggregates tended to be higher in TAC animals compared to sham controls. Since platelets can dynamically modulate perivascular inflammation, we investigated the impact of thrombocytopenia on the response to TAC. Immunodepletion of platelets decreased early perivascular T lymphocytes' accumulation and altered subsequent coronary artery remodeling. The contribution of lymphocytes were examined in Rag1−/− mice, which displayed significantly more intimal hyperplasia and perivascular fibrosis compared to wild-type mice following TAC. Collectively, our studies support a role of early perivascular accumulation of platelets and T lymphocytes in pressure overload-induced inflammation.
The Fitness-Corrected Block Model, or how to create maximum-entropy data-driven spatial social networks
Creators: name: Bernaschi, Massimo
name: Celestini, Alessandro
name: Guarino, Stefano
name: Mastrostefano, Enrico
name: Saracco, Fabio
Publisher: name: arXiv
Year: 2022
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Social and Information Networks (cs.SI)
subject: Data Analysis, Statistics and Probability (physics.data-an)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Models of networks play a major role in explaining and reproducing empirically observed patterns. Suitable models can be used to randomize an observed network while preserving some of its features, or to generate synthetic graphs whose properties may be tuned upon the characteristics of a given population. In the present paper, we introduce the Fitness-Corrected Block Model, an adjustable-density variation of the well-known Degree-Corrected Block Model, and we show that the proposed construction yields a maximum entropy model. When the network is sparse, we derive an analytical expression for the degree distribution of the model that depends on just the constraints and the chosen fitness-distribution. Our model is perfectly suited to define maximum-entropy data-driven spatial social networks, where each block identifies vertices having similar position (e.g., residence) and age, and where the expected block-to-block adjacency matrix can be inferred from the available data. In this case, the sparse-regime approximation coincides with a phenomenological model where the probability of a link binding two individuals is directly proportional to their sociability and to the typical cohesion of their age-groups, whereas it decays as an inverse-power of their geographic distance. We support our analytical findings through simulations of a stylized urban area.
description: 14 pages, 1 figure
Hydrodynamic provinces and oceanic connectivity from a transport network help designing marine reserves
Creators: name: Rossi, Vincent
name: Ser-Giacomi, Enrico
name: López, Cristóbal
name: Hernández-García, Emilio
Publisher: name: arXiv
Year: 2014
Subjects: subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: Oceanic dispersal and connectivity have been identified as crucial factors for structuring marine populations and designing Marine Protected Areas (MPAs). Focusing on larval dispersal by ocean currents, we propose an approach coupling Lagrangian transport and new tools from Network Theory to characterize marine connectivity in the Mediterranean basin. Larvae of different pelagic durations and seasons are modeled as passive tracers advected in a simulated oceanic surface flow from which a network of connected areas is constructed. Hydrodynamical provinces extracted from this network are delimited by frontiers which match multi-scale oceanographic features. By examining the repeated occurrence of such boundaries, we identify the spatial scales and geographic structures that would control larval dispersal across the entire seascape. Based on these hydrodynamical units, we study novel connectivity metrics for existing reserves. Our results are discussed in the context of ocean biogeography and MPAs design, having ecological and managerial implications.
Rethinking the Role of Interference in Wireless Networks
Creators: name: Zheng, Gan
name: Krikidis, Ioannis
name: Masouros, Christos
name: Timotheou, Stelios
name: Toumpakaris, Dimitris-Alexandros
name: Ding, Zhiguo
Publisher: name: arXiv
Year: 2014
Subjects: subject: Information Theory (cs.IT)
subject: FOS: Computer and information sciences

description: This article re-examines the fundamental notion of interference in wireless networks by contrasting traditional approaches to new concepts that handle interference in a creative way. Specifically, we discuss the fundamental limits of the interference channel and present the interference alignment technique and its extension of signal alignment techniques. Contrary to this traditional view, which treats interference as a detrimental phenomenon, we introduce three concepts that handle interference as a useful resource. The first concept exploits interference at the modulation level and leads to simple multiuser downlink precoding that provides significant energy savings. The second concept uses radio frequency radiation for energy harvesting and handles interference as a source of green energy. The last concept refers to a secrecy environment and uses interference as an efficient means to jam potential eavesdroppers. These three techniques bring a new vision about interference in wireless networks and motivate a plethora of potential new applications and services.
description: 6 figures, accepted in IEEE Communications Magazine
Cryptopleurine Analogs with Modification of E Ring Exhibit Different Mechanism to Rac-Cryptopleurine and Tylophorine
Creators: name: Yang, Xiaoming
name: Wang, Ying
name: Gullen, Elizabeth A.
name: Lee, Kuo-Hsiung
name: Lam, Wing
name: Cheng, Yung-Chi
name: Wong, Hui-Chyn
name: Shi, Qian
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Tylophorine analogs exhibit a broad range of pharmacological activities, including anti-cancer, anti-inflammatory, anti-autoimmune, and anti-virus effects. Structure-activity relationship study of different structure tylophorine analogs can provide further understanding of their biological activity. Modifications on the E ring of the quinolizidine moiety of cryptopleurine analogs changed the potency and the selective inhibitory effect on NF-κB, AP-1, and CRE signaling pathways. Functional cryptopleurine analogs showed potent inhibition of NF-κB signaling pathway in both HepG2 and HEK-293 cell lines. The E ring structure analogs also differed in suppression of protein translation, and expression of cyclin D1. Our results showed that DCB-3503 or Rac-cryptopleurine could be a scaffold for modification to yield compounds with different mechanisms of action.
Fannie Mae National Housing Survey Monthly Key Indicators--June, 2012 (a subset of the complete monthly Fannie Mae National Housing Survey)
Creators: name: Foundation, Fannie Mae
Publisher: name: Roper Center for Public Opinion Research
Year: 2019

description: Economy on right/wrong track (1); personal financial situation (1); good/bad time to buy a house (1); good/bad time to sell a house (1); home price changes (3); rental price changes (3); mortgage interest rate changes (1); ability to obtain a home mortgage today (1); current homeownership status (1); renting vs. buying a home in the future (1); change in income (1); household expenses (1).
Constraining Parameters of Generalized Cosmic Chaplygin Gas in Loop Quantum Cosmology
Creators: name: Ranjit, Chayan
name: Debnath, Ujjal
Publisher: name: arXiv
Year: 2014
Subjects: subject: General Physics (physics.gen-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We have assumed the FRW universe in loop quantum cosmology (LQC) model filled with the dark matter and the Generalized Cosmic Chaplygin gas (GCCG) type dark energy where dark matter follows the linear equation of state. We present the Hubble parameter in terms of the observable parameters $Ω_{m0}$ and $H_{0}$ with the redshift $z$ and the other parameters like $A$, $B$, $w_{m}$, $ ω$ and $α$ which coming from our model. From Stern data set (12 points)\& SNe Type Ia 292 data (from \cite{Riess1,Riess2,Astier}) we have obtained the bounds of the arbitrary parameters by minimizing the $χ^{2}$ test. The best-fit values of the parameters are obtained by 66\%, 90\% and 99\% confidence levels. Next due to joint analysis with Stern+BAO and Stern+BAO+CMB observations, we have also obtained the bounds of the parameters ($A,B$) by fixing some other parameters $α$, $w_{m}$ and $ω$. From the best fit values of the parameters, we have obtained the distance modulus $μ(z)$ for our theoretical GCCG model in LQC and from Supernovae Type Ia (union2 sample 552 data from [\cite{Amanullah}] \& Riess 292 data from [\cite{Riess1,Riess2,Astier}]), we have concluded that our model is in agreement with the Supernovae Type Ia sample data. In addition, we have investigated in details about the various types of Future Singularities that may be formed in this model and it is notable that our model is completely free from any types of future singularities.
description: 36 pages, 15 figures, Accepted in Astrophysics and Space Science (2014). arXiv admin note: substantial text overlap with arXiv:1206.0507, arXiv:1304.6713, arXiv:1406.3043
The influence of proximity induced ferromagnetism, superconductivity and Fermi-velocity on evolution of Berry phase in Bi$_{2}$Se$_{3}$ topological insulator
Creators: name: Sengupta, Parijat
Publisher: name: arXiv
Year: 2014
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Bi$_{2}$Se$_{3}$ is a well known 3D-topological insulators(TI) with a non-trivial Berry phase of $ \left(2n+1\right)π$ attributed to the topology of the band structure. The Berry phase shows non-topological deviations from $ \left(2n+1\right)π$ in presence of a perturbation that destroys time reversal symmetry and gives rise to a quantum system with massive Dirac fermions and finite band gap. Such a band gap opening is achieved on account of the exchange field of a ferromagnet or the intrinsic energy gap of a superconductor that influences the topological insulator surface states by virtue of the proximity effect. In this work Berry phase of such gapped systems with massive Dirac fermions is considered. Additionally, it is shown that the Berry phase for such a system also depends on the \textit{Fermi}-velocity of the surface states which can be tuned as a function of the TI film thickness.
description: 6 pages, 4 figures
Cystatin A, a Potential Common Link for Mutant Myocilin Causative Glaucoma
Creators: name: Kennedy, K. David
name: Buie, LaKisha K.
name: Borrás, Teresa
name: AnithaChristy, S. A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Myocilin (MYOC) is a 504 aa secreted glycoprotein induced by stress factors in the trabecular meshwork tissue of the eye, where it was discovered. Mutations in MYOC are linked to glaucoma. The glaucoma phenotype of each of the different MYOC mutation varies, but all of them cause elevated intraocular pressure (IOP). In cells, forty percent of wild-type MYOC is cleaved by calpain II, a cysteine protease. This proteolytic process is inhibited by MYOC mutants. In this study, we investigated the molecular mechanisms by which MYOC mutants cause glaucoma. We constructed adenoviral vectors with variants Q368X, R342K, D380N, K423E, and overexpressed them in human trabecular meshwork cells. We analyzed expression profiles with Affymetrix U133Plus2 GeneChips using wild-type and null viruses as controls. Analysis of trabecular meshwork relevant mechanisms showed that the unfolded protein response (UPR) was the most affected. Search for individual candidate genes revealed that genes that have been historically connected to trabecular meshwork physiology and pathology were altered by the MYOC mutants. Some of those had known MYOC associations (MMP1, PDIA4, CALR, SFPR1) while others did not (EDN1, MGP, IGF1, TAC1). Some, were top-changed in only one mutant (LOXL1, CYP1B1, FBN1), others followed a mutant group pattern. Some of the genes were new (RAB39B, STC1, CXCL12, CSTA). In particular, one selected gene, the cysteine protease inhibitor cystatin A (CSTA), was commonly induced by all mutants and not by the wild-type. Subsequent functional analysis of the selected gene showed that CSTA was able to reduce wild-type MYOC cleavage in primary trabecular meshwork cells while an inactive mutated CSTA was not. These findings provide a new molecular understanding of the mechanisms of MYOC-causative glaucoma and reveal CSTA, a serum biomarker for cancer, as a potential biomarker and drug for the treatment of MYOC-induced glaucoma.
Defining Components of the ？catenin Destruction Complex and Exploring Its Regulation and Mechanisms of Action during Development
Creators: name: Roberts, David M.
name: Rogers, Gregory C.
name: Peifer, Mark
name: Jung, Kuo-Chen
name: Poulton, John S.
name: McKay, Daniel J.
name: Schneider, Daniel E.
name: Pronobis, Mira I.
name: Alexandre, Kelly M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Background A subset of signaling pathways play exceptionally important roles in embryonic and post-embryonic development, and mis-regulation of these pathways occurs in most human cancers. One such pathway is the Wnt pathway. The primary mechanism keeping Wnt signaling off in the absence of ligand is regulated proteasomal destruction of the canonical Wnt effector ？catenin (or its fly homolog Armadillo). A substantial body of evidence indicates that SCFβTrCP mediates βcat destruction, however, an essential role for Roc1 has not been demonstrated in this process, as would be predicted. In addition, other E3 ligases have also been proposed to destroy βcat, suggesting that βcat destruction may be regulated differently in different tissues. Methodology/Principal Findings Here we used cultured Drosophila cells, human colon cancer cells, and Drosophila embryos and larvae to explore the machinery that targets Armadillo for destruction. Using RNAi in Drosophila S2 cells to examine which SCF components are essential for Armadillo destruction, we find that Roc1/Roc1a is essential for regulating Armadillo stability, and that in these cells the only F-box protein playing a detectable role is Slimb. Second, we find that while embryonic and larval Drosophila tissues use the same destruction complex proteins, the response of these tissues to destruction complex inactivation differs, with Armadillo levels more elevated in embryos. We provide evidence consistent with the possibility that this is due to differences in armadillo mRNA levels. Third, we find that there is no correlation between the ability of different APC2 mutant proteins to negatively regulate Armadillo levels, and their recently described function in positively-regulating Wnt signaling. Finally, we demonstrate that APC proteins lacking the N-terminal Armadillo-repeat domain cannot restore Armadillo destruction but retain residual function in negatively-regulating Wnt signaling. Conclusions/Significance We use these data to refine our model for how Wnt signaling is regulated during normal development.
Dehydrocostuslactone Suppresses Angiogenesis In Vitro and In Vivo through Inhibition of Akt/GSK-3β and mTOR Signaling Pathways
Creators: name: Pan, Shiow-Lin
name: Lee, Kuo-Hsiung
name: Peng, Chieh-Yu
name: Tsai, An-Chi
name: Teng, Che-Ming
name: Chang, Ya-Ling
name: Wang, Chih-Ya
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The traditional Chinese medicine component dehydrocostuslactone (DHC) isolated from Saussurea costus (Falc.) Lipschitz, has been shown to have anti-cancer activity. Angiogenesis is an essential process in the growth and progression of cancer. In this study, we demonstrated, for the first time, the anti-angiogenic mechanism of action of DHC to be via the induction of cell cycle progression at the G0/G1 phase due to abrogation of the Akt/glycogen synthase kinase-3β (GSK-3β)/cyclin D1 and mTOR signaling pathway. First, we demonstrated that DHC has an anti-angiogenic effect in the matrigel-plug nude mice model and an inhibitory effect on human umbilical vein endothelial cell (HUVEC) proliferation and capillary-like tube formation in vitro. DHC caused G0/G1 cell cycle arrest, which was associated with the down-regulation of cyclin D1 expression, leading to the suppression of retinoblastoma protein phosphorylation and subsequent inhibition of cyclin A and cdk2 expression. With respect to the molecular mechanisms underlying the DHC-induced cyclin D1 down-regulation, this study demonstrated that DHC significantly inhibits Akt expression, resulting in the suppression of GSK-3β phosphorylation and mTOR expression. These effects are capable of regulating cyclin D1 degradation, but they were significantly reversed by constitutively active myristoylated (myr)-Akt. Furthermore, the abrogation of tube formation induced by DHC was also reversed by overexpression of Akt. And the co-treatment with LiCl and DHC significantly reversed the growth inhibition induced by DHC. Taken together, our study has identified Akt/GSK-3β and mTOR as important targets of DHC and has thus highlighted its potential application in angiogenesis-related diseases, such as cancer.
Detection of PIGO-Deficient Cells Using Proaerolysin: A Valuable Tool to Investigate Mechanisms of Mutagenesis in the DT40 Cell System
Creators: name: Swenberg, James A.
name: Bultman, Scott J.
name: Nakamura, Jun
name: Gul, Husamettin
name: Tian, Xu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: While isogenic DT40 cell lines deficient in DNA repair pathways are a great tool to understand the DNA damage response to genotoxic agents by a comparison of cell toxicity in mutants and parental DT40 cells, no convenient mutation assay for mutagens currently exists for this reverse-genetic system. Here we establish a proaerolysin (PA) selection-based mutation assay in DT40 cells to identify glycosylphosphatidylinositol (GPI)-anchor deficient cells. Using PA, we detected an increase in the number of PA-resistant DT40 cells exposed to MMS for 24 hours followed by a 5-day period of phenotype expression. GPI anchor synthesis is catalyzed by a series of phosphatidylinositol glycan complementation groups (PIGs). The PIG-O gene is on the sex chromosome (Chromosome Z) in chicken cells and is critical for GPI anchor synthesis at the intermediate step. Among all the mutations detected in the sequence levels observed in DT40 cells exposed to MMS at 100 µM, we identified that ∼55% of the mutations are located at A:T sites with a high frequency of A to T transversion mutations. In contrast, we observed no transition mutations out of 18 mutations. This novel assay for DT40 cells provides a valuable tool to investigate the mode of action of mutations caused by reactive agents using a series of isogenic mutant DT40 cells.
A first order prolongation of the conventional space
Creators: name: Matsyuk, R. Ya.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Differential Geometry (math.DG)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics
subject: 53B40, 58E30, 70H50, 49N45

description: A variational equation of the third order in three-dimensional space is proposed which describes autoparallel curves of some connection.
description: 3 figures. MR1406360 (97e:58061); Zbl 0867.58021. Corrected after publ.: Formulae (24), (28), equation numbering, typos on p. 404, references
Diabetes Medication Use and Blood Lactate Level among Participants with Type 2 Diabetes: The Atherosclerosis Risk in Communities Carotid MRI Study
Creators: name: Mongraw-Chaffin, Morgana L.
name: Matsushita, Kunihiro
name: Brancati, Frederick L.
name: Young, Jeffery Hunter
name: Crawford, Stephen O.
name: Coresh, Josef
name: Hoogeveen, Ron C.
name: Ballantyne, Christie M.
name: Schmidt, Maria Inês
name: Astor, Brad C.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: BackgroundThe objective of this study is to compare lactate levels between users and non-users of diabetes medications under the hypothesis that the level of lactate is a marker of oxidative capacity.MethodsThe cross-sectional data of 493 participants aged 61–84 with type 2 diabetes who participated in the Atherosclerosis Risk in Communities Carotid MRI study were analyzed using survey weighted linear regression.ResultsMedian plasma lactate level was 8.58 (95% CI: 8.23, 8.87) mg/dl. Comparing users of diabetic medications with non-users, thiazolidinedione use was significantly associated with lower lactate level (7.57 (6.95–8.25) mg/dL vs. 8.78 (8.43–9.14) mg/dL), metformin use with a slightly higher lactate level (9.02 (8.51–9.58) mg/dL vs. 8.36 (7.96–8.77) mg/dL), and sulfonylurea and insulin use were not associated with lactate level. After adjustment for demographic and lifestyle factors, the plasma lactate level for thiazolidinedione users was 15.78% lower than that for non-users (p<0.001). Considering use of each medication separately and in combination did not change the results.ConclusionIn conclusion, thiazolidinedione use was associated with lower plasma lactate level compared to non-use and metformin use was only marginally associated with a slightly higher lactate level. These results are consistent with the previously demonstrated effects of diabetes medications on oxidative metabolism. Further investigation of the role that diabetes medications play in improvement of oxidative metabolism is warranted.