cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Impact of the inherent periodic structure on the effective medium description of left-handed and related meta-materials
Creators: name: Koschny, Th.
name: Markos, P.
name: Economou, E. N.
name: Smith, D. R.
name: Vier, D. C.
name: Soukoulis, C. M.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: We study the frequency dependence of the effective electromagnetic parameters of left-handed and related meta-materials of the split ring resonator and wire type. We show that the reduced translational symmetry (periodic structure) inherent to these meta-materials influences their effective electromagnetic response. To anticipate this periodicity, we formulate a periodic effective medium model which enables us to distinguish the resonant behavior of electromagnetic parameters from effects of the periodicity of the structure. We use this model for the analysis of numerical data for the transmission and reflection of periodic arrays of split ring resonators, thin metallic wires, cut wires as well as the left-handed structures. The present method enables us to identify the origin of the previously observed resonance/anti-resonance coupling as well as the occurrence of negative imaginary parts in the effective permittivities and permeabilities of those materials. Our analysis shows that the periodicity of the structure can be neglected only for the wavelength of the electromagnetic wave larger than 30 space periods of the investigated structure.
description: 23 pages, 14 figures
Probing the Z = 6 spin-orbit shell gap with (p,2p) quasi-free scattering reactions
Creators: name: Syndikus, I.
name: Petri, M.
name: Macchiavelli, A. O.
name: Paschalis, S.
name: Bertulani, C. A.
name: Aumann, T.
name: Alvarez-Pol, H.
name: Atar, L.
name: Beceiro-Novo, S.
name: Benlliure, J.
name: Boillos, J. M.
name: Boretzky, K.
name: Borge, M. J. G.
name: Brown, B. A.
name: Caamaño, M.
name: Caesar, C.
name: Casarejos, E.
name: Catford, W.
name: Cederkall, J.
name: Chulkov, L. V.
name: Cortina-Gil, D.
name: Cravo, E.
name: Crespo, R.
name: Dillmann, I.
name: Fernández, P. Díaz
name: Elekes, Z.
name: Enders, J.
name: Farinon, F.
name: Fraile, L. M.
name: Redondo, D. Galaviz
name: Geissel, H.
name: Gernhäuser, R.
name: Golubev, P.
name: Göbel, K.
name: Heil, M.
name: Heine, M.
name: Heinz, A.
name: Henriques, A.
name: Holl, M.
name: Johansson, H. T.
name: Jonson, B.
name: Kalantar-Nayestanaki, N.
name: Kanungo, R.
name: Kelic-Heil, A.
name: Kröll, T.
name: Kurz, N.
name: Langer, C.
name: Bleis, T. Le
name: Machado, J. F. D. C.
name: Marganiec-Gałazka, J.
name: Nacher, E.
name: Nilsson, T.
name: Nociforo, C.
name: Panin, V.
name: Perea, A.
name: Pietri, S. B.
name: Plag, R.
name: Reifarth, R.
name: Revel, A.
name: Ribeiro, G.
name: Rigollet, C.
name: Rossi, D. M.
name: Savran, D.
name: Scheit, H.
name: Simon, H.
name: Sorlin, O.
name: Tengblad, O.
name: Togano, Y.
name: Vandebrouck, M.
name: Volkov, V.
name: Wheldon, F. Wamers C.
name: Wilson, G. L.
name: Winfield, J. S.
name: Weick, H.
name: Woods, P.
name: Yakorev, D.
name: Zhukov, M.
name: Zilges, A.
name: Zuber, K.
Publisher: name: arXiv
Year: 2020
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: The evolution of the traditional nuclear magic numbers away from the valley of stability is an active field of research. Experimental efforts focus on providing key spectroscopic information that will shed light into the structure of exotic nuclei and understanding the driving mechanism behind the shell evolution. In this work, we investigate the Z = 6 spin-orbit shell gap towards the neutron dripline. To do so, we employed $^{A}$N(p,2p)$^{A-1}$C quasi-free scattering reactions to measure the proton component of the 2$^+_1$ state of $^{16,18,20}$C. The experimental findings support the notion of a moderate reduction of the proton 1p$_{1/2}$-1p$_{3/2}$ spin-orbit splitting, at variance to recent claims for a prevalent Z = 6 magic number towards the neutron dripline.
description: 27 pages, 5 figures, 2 tables. Submitted to Physics Letter B
Peptide backbone orientation and dynamics in spider dragline silk and two-photon excitation in nuclear magnetic and quadrupole resonance
Creators: name: Eles, Philip Thomas
Publisher: name: University of British Columbia
Year: 2009

description: In the first part of the dissertation, spider dragline silk is studied by solid state NMR techniques. The dependence of NMR frequency on molecular orientation is exploited using the DECODER experiment to determine the orientation of the protein backbone within the silk fibre. Practical experimental considerations require that the silk fibres be wound about a cylindrical axis perpendicular to the external magnetic field, complicating the reconstruction of the underlying orientation distribution and necess-itating the development of numerical techniques for this purpose. A two-component model of silk incorporating static b-sheets and polyglycine II helices adequately fits the NMR data and suggests that the b-sheets are well aligned along the silk axis (20 FWHM) while the helices are poorly aligned (68 FWHM). The effects of fibre strain, draw rate and hydration on orientation are measured. Measurements of the time-scale for peptide backbone motion indicate that when wet, a strain-dependent frac-tion of the poorly aligned component becomes mobile. This suggests a mechanism for the supercontraction of silk involving latent entropic springs that undergo a local straindependent phase transition, driving supercontraction. In the second part of this dissertation a novel method is developed for exciting NMR and nuclear quadrupole resonance (NQR) by rf irradiation at multiple frequencies that sum to (or differ by) the resonance frequency. This is fundamentally different than traditional NMR experiments where irradiation is applied on-resonance. With excitation outside the detection bandwidth, two-photon excitation allows for detection of free induction signals during excitation, completely eliminating receiver dead-time. A theoretical approach to describing two-photon excitation is developed based on average Hamiltonian theory. An intuition for two-photon excitation is gained by analogy to the coherent absorption of multiple photons requiring conservation of total energy and momentum. It is shown that two-photon excitation efficiency impro-ves when the two applied rf frequencies deviate from half-resonance. For two-photon NQR, it is shown that observable magnetization appears perpendicular to the excita-tion coil, requiring a second coil for detection, and that double quantum coherences are also generated. Several model systems and experimental geometries are used to demonstrate the peculiarities of two-photon excitation in NMR and NQR.
title: Éric Favereau, "Gallo-Montagnier : nouvelles étincelles"
Creators: name: Favereau, Éric (1955?-....)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: article extrait de Libération, 1er-2 juin 1991.
description: Source: http://www.calames.abes.fr/pub/ms/Calames-2019311123551036
description: created: start=1991-06-01;end=1991-06-02
Continuity bounds on the quantum relative entropy
Creators: name: Audenaert, K. M. R.
name: Eisert, J.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Quantum Physics (quant-ph)
subject: Mathematical Physics (math-ph)
subject: FOS: Physical sciences

description: The quantum relative entropy is frequently used as a distance, or distinguishability measure between two quantum states. In this paper we study the relation between this measure and a number of other measures used for that purpose, including the trace norm distance. More precisely, we derive lower and upper bounds on the relative entropy in terms of various distance measures for the difference of the states based on unitarily invariant norms. The upper bounds can be considered as statements of continuity of the relative entropy distance in the sense of Fannes. We employ methods from optimisation theory to obtain bounds that are as sharp as possible.
description: 13 pages (ReVTeX), 3 figures, replaced with published version
Additional file 1 of Addressing the quality and scope of paediatric primary care in South Africa: evaluating contextual impacts of the introduction of the Practical Approach to Care Kit for children (PACK Child)
Creators: name: Murdoch, Jamie
name: Curran, Robyn
name: Cornick, Ruth
name: Picken, Sandy
name: Bachmann, Max
name: Bateman, Eric
name: Makhosazana Lungile Simelane
name: Fairall, Lara
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Additional file 1. Child > 2 months old: Routine Care. Sample of routine care page from PACK Child guide.
Additional file 3 of Genome-wide characterization of tea plant (Camellia sinensis) Hsf transcription factor family and role of CsHsfA2 in heat tolerance
Creators: name: Xuyang Zhang
name: Wenluan Xu
name: Dejiang Ni
name: Wang, Mingle
name: Guiyi Guo
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 3: Table S2. List of predicted miRNA target sites of CsHsf genes.
Quality Labels and Firm Survival in the Food Industry
Creators: name: Bontemps, Christophe
name: Bouamra-Mechemache, Zohra
name: Simioni, Michel
name: Bontemps, Christophe
name: Bouamra-Mechemache, Zohra
name: Simioni, Michel
Publisher: name: Unknown
Year: 2011
Subjects: Agribusiness

description: Both industry and firm characteristics influence the survival of a firm in an industry over time. Aging, size, structure are factors often discussed in the literature, but public intervention effects - through public quality labeling for example - may also have an effect that is examined here. We use data on French firms producing cheese under public quality label or not over the period 1990-2006. We perform a nonparametric estimation using Kaplan-Meier estimators as well as proportional hazard rate models to assess the impact of such factors on firms survival. Our results confirm existing finding on firm survival determinants. We also shed light on the effect of public intervention into that industry. More precisely, our focus on public quality labeling in the French cheese industry shows that quality label reduces the risk of exiting for firms and more particularly for small firms. In other words, public intervention in this industry is well designed to increase the competitiveness of small firms enabling the coexistence on the market of both small and large firms.
A multi-dimensional, adiabatic, hydrodynamics code for studying tidal excitation
Creators: name: Broderick, Avery E.
name: Rathore, Yasser
Publisher: name: arXiv
Year: 2004
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We have developed a parallel, simple, and fast hydrodynamics code for multi-dimensional, self-gravitating, adiabatic flows. Our primary motivation is the study of the non-linear evolution of white dwarf oscillations excited via tidal resonances, typically over hundreds of stellar dynamical times. Consequently, we require long term stability, low diffusivity, and high algorithmic efficiency. An explicit, Eulerian, finite-difference scheme on a regular Cartesian grid fulfills these requirements. It provides uniform resolution throughout the flow, as well as simplifying the computation of the self-gravitational potential, which is done via spectral methods. In this paper, we describe the numerical scheme and present the results of some diagnostic problems. We also demonstrate the stability of a cold white dwarf in three dimensions over hundreds of dynamical times. Finally, we compare the results of the numerical scheme to the linear theory of adiabatic oscillations, finding numerical quality factors on the order of 6000, and excellent agreement with the oscillation frequency obtained by the linear analysis.
description: 11 pages, 10 figures
Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: in vitro and in vivo analyses
Creators: name: Sibgha Batool
name: Zahid, Fatima
name: Fakhar- Ud-Din
name: Naz, Syeda Sohaila
name: Dar, Muhammad Junaid
name: Khan, Muhammad Waseem
name: Zeb, Alam
name: Khan, Gul Majid
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: The purpose of this study was to develop novel carbopol-based miltefosine-loaded transfersomal gel (HePCTG) for the treatment of cutaneous leishmaniasis (CL) via efficient targeting of leishmania infected macrophages. Miltefosine-loaded transfersomes (HePCT) were prepared by ethanol injection method followed by their incorporation into carbopol gel to form HePCTG. The prepared HePCT were assessed for physicochemical properties including mean particle size, polydispersity index, zeta potential, entrapment efficiency, morphology, and deformability. Similarly, HePCTG was evaluated for physiochemical and rheological attributes. The in vitro release, skin permeation, skin irritation, anti-leishmanial activity, and in vivo efficacy in BALB/c mice against infected macrophages were also performed for HePCT. The optimized HePCT displayed a particle size of 168 nm with entrapment efficiency of 92%. HePCTG showed suitable viscosity, pH, and sustained release of the incorporated drug. Furthermore, HePCT and HePCTG demonstrated higher skin permeation than drug solution. The results of macrophage uptake study indicated improved drug intake by passive diffusion. The lower half maximal inhibitory concentration value, selectivity index and higher 50% cytotoxic concentration value of HePCT compared to that of HePC solution demonstrated the improved anti-leishmanial efficacy and non-toxicity of the formulation. This was further confirmed by the notable reduction in parasite load and lesion size observed in in vivo anti-leishmanial study. It can be stated that the formulated HePCTG can effectively be used for the treatment of CL.
Eliciting Risk Preferences: A Field Experiment on a Sample of French Farmers
Creators: name: Bougherara, Douadia
name: Gassmann, Xavier
name: Piet, Laurent
name: Bougherara, Douadia
name: Gassmann, Xavier
name: Piet, Laurent
Publisher: name: Unknown
Year: 2011
Subjects: subject: Risk and Uncertainty
subject: Risk Attitudes
subject: Field Experiment
subject: Farming

description: We designed a field experiment involving real payments to elicit farmers’ risk preferences. Farmers are a very interesting sample to study since risk has always played an important role in agricultural producers’ decisions. Besides, European farmers may face more risky situations in the future. In this context, it is very important for any economic analysis focusing on agriculture to correctly assess farmers’ behaviour in the face of different sources of risk. We test for two descriptions of farmers’ behaviour: expected utility and cumulative prospect theory. We use two elicitation methods based on the procedures of Holt and Laury (2002) and Tanaka et al. (2010) on a sample of 30 French farmers. The experiment consists in asking subjects to make series of choices between two lotteries with varying probabilities and outcomes. We estimate parameters describing farmers’ risk preferences derived from structural models. We find farmers are slightly risk averse in the expected utility framework. In the cumulative prospect theory frame, we find farmers display either loss aversion or probability weighting, tending to overweight small probabilities and to underweight high probabilities. In our study, expected utility is not a good description of farmers’ behaviour towards risk.
Development and characterization of pluronic lecithin organogel containing fluocinolone acetonide
Creators: name: Dinal Patel
name: Viral Patel
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: The rabble-rousing skin condition can be conventionally treated, but due to some demerits, there is a need to find a novel approach with an appropriate release profile. The research work narrates the optimization of the topical delivery system of Fluocinolone acetonide loaded in pluronic lecithin organogel. The preliminary studies were carried out and, the ternary phase diagram was established by Chemix school version 3.60. The formulation was optimized by taking a different concentration of polymers as independent and viscosity and drug release (6 h) as dependent variables by applying 32 full factorial design. The optimized batch was further compared with marketed preparation and also kept for the stability study. The release profile of the optimized batch exhibited a sustained release of up to 6 h (77.00%). It gave ex vivo drug release up to 6 h (90.64%) which is more prolonged than marketed preparation and, cutaneous disposition was found to be higher. Besides, the texture analysis was compared to that of the marketed formulation of the drug. However, the proof of the effectiveness of the formulated pluronic lecithin organogel will require further in vivo study for future aspects. In a nutshell, the proposed formulation of fluocinolone acetonide is the simplest and promising dosage form for the treatment of psoriasis.
Limiting the Nitrogen Losses by N-tax and Bioenergy Support: A Quantitative Analysis of Environmental Policy Mix Impacts in the North of France
Creators: name: Fradj, Nosra Ben
name: Bourgeois, Cyril
name: Clodic, Melissa
name: Jayet, Pierre-Alain
name: Fradj, Nosra Ben
name: Bourgeois, Cyril
name: Clodic, Melissa
name: Jayet, Pierre-Alain
Publisher: name: Unknown
Year: 2011
Subjects: subject: Environmental Economics and Policy
subject: Bio-economic model
subject: mathematical linear programming
subject: environmental policy mix
subject: N-fertilizer tax
subject: bio-energy support

description: This paper is devoted to assessment of policy mix impacts regarding nitrogen pollutants. The analysed policy combines a tax on the nitrogen input and incentives promoting perennial crops assumed to be low input ones. We show that perennial crop subsidy increases significantly the tax efficiency, compatible with the balanced budget of the Regulatory Agency in charge of the environment. Based on a MILP agricultural supply model, quantitative analysis provides assessment of impacts regarding land use, farmers income, and N losses at the North France level.
Simple Hand-Held Calculating Unit to Aid the Visually Impaired with Voice Output
Creators: name: GANGOPADHYAY, SHREEDEEP
Publisher: name: Zenodo
Year: 2015

description: A thorough understanding in mathematics enhances educational and occupational opportunities for all, whether sighted or visually impaired.. However, solving complicated mathematical problems is difficult for visually challenged students in schools and universities as the calculators available in the markets with smooth input keys and LCD outputs are useless for them. Using the assistive technology which is basically a service or product to help people with disabilities function more independently has removed barriers to educate and employ people. An optimal solution for them is Braille calculator with audio output. In this paper, we have proposed a cost effective, hand-held, battery-driven, low power assistive device aiming the visually impaired people from low income settings. The input is given through a 4 by 4 Membrane keypad which has been Braille-embossed using indigenous methods. The output is announced in natural English by the audio unit via speakers and/or headphones up to two places of decimal point. The system is implemented on custom made open source Arduino platform, making it efficient and cost-effective
Stabilization of transmittance fluctuations caused by beam wandering in continuous-variable quantum communication over free-space atmospheric channels
Creators: name: Usenko, Vladyslav C.
name: Peuntinger, Christian
name: Heim, Bettina
name: Günthner, Kevin
name: Derkach, Ivan
name: Elser, Dominique
name: Marquardt, Christoph
name: Filip, Radim
name: Leuchs, Gerd
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Transmittance fluctuations in turbulent atmospheric channels result in quadrature excess noise which limits applicability of continuous-variable quantum communication. Such fluctuations are commonly caused by beam wandering around the receiving aperture. We study the possibility to stabilize the fluctuations by expanding the beam, and test this channel stabilization in regard of continuous-variable entanglement sharing and quantum key distribution. We perform transmittance measurements of a real free-space atmospheric channel for different beam widths and show that the beam expansion reduces the fluctuations of the channel transmittance by the cost of an increased overall loss. We also theoretically study the possibility to share an entangled state or to establish secure quantum key distribution over the turbulent atmospheric channels with varying beam widths. We show the positive effect of channel stabilization by beam expansion on continuous-variable quantum communication as well as the necessity to optimize the method in order to maximize the secret key rate or the amount of shared entanglement. Being autonomous and not requiring adaptive control of the source and detectors based on characterization of beam wandering, the method of beam expansion can be also combined with other methods aiming at stabilizing the fluctuating free-space atmospheric channels.
description: \copyright 2018 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved
Additional file 1 of Genome-wide characterization of tea plant (Camellia sinensis) Hsf transcription factor family and role of CsHsfA2 in heat tolerance
Creators: name: Xuyang Zhang
name: Wenluan Xu
name: Dejiang Ni
name: Wang, Mingle
name: Guiyi Guo
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 1: Figure S1. The distribution of conserved motifs and their corresponding sequence logos of CsHsf proteins. a 25 conserved motifs of CsHsf proteins were analyzed by MEME (http://meme-suite.org/tools/meme). b Sequence logos of the 25 conserved motifs.
Block factorization of the relative entropy via spatial mixing
Creators: name: Caputo, Pietro
name: Parisi, Daniel
Publisher: name: arXiv
Year: 2020
Subjects: subject: Probability (math.PR)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 82B20, 82C20, 39B62

description: We consider spin systems in the $d$-dimensional lattice $Z^d$ satisfying the so-called strong spatial mixing condition. We show that the relative entropy functional of the corresponding Gibbs measure satisfies a family of inequalities which control the entropy on a given region $V\subset Z^d$ in terms of a weighted sum of the entropies on blocks $A\subset V$ when each $A$ is given an arbitrary nonnegative weight $α_A$. These inequalities generalize the well known logarithmic Sobolev inequality for the Glauber dynamics. Moreover, they provide a natural extension of the classical Shearer inequality satisfied by the Shannon entropy. Finally, they imply a family of modified logarithmic Sobolev inequalities which give quantitative control on the convergence to equilibrium of arbitrary weighted block dynamics of heat bath type.
description: 23 pages, 2 figures
Estimating the Resilience Value of Soil Biodiversity in Agriculture: A Stochastic Simulation Approach
Creators: name: Brady, Mark
name: Cong, RongGang
name: Brady, Mark
name: Cong, RongGang
Publisher: name: Unknown
Year: 2011
Subjects: Resource /Energy Economics and Policy

description: Characteristic of ecosystems is that different organisms can have similar functions and hence provide similar ecosystem services. Consequently functional diversity can maintain the rate of services despite environmental fluctuations. In this paper we present a method for estimating the resilience value of biodiversity. Central to a resilience perspective on biological conservation is consideration of uncertainty about the future. To do this we propose stochastic simulation as a practical approach for valuing resilience due to the ease of incorporating uncertain variables. We demonstrate the approach by developing a stochastic simulation model for valuing soil biodiversity in agriculture. Our results indicate that the long time frames involved in soil processes create a significant incentive to perpetuate unsustainable farming systems and hence there might be a need for policy intervention. However we also show that investing in soil biodiversity conservation can provide significant risk diversification benefits that are not accounted for in a deterministic evaluation. These benefits can be estimated through stochastic simulation.
Determinants of Economic Growth in Organic Farming: The Case of Bavaria and Baden-Wuerttemberg
Creators: name: Brenes Muñoz, Thelma
name: Lakner, Sebastian
name: Brümmer, Bernhard
name: Brenes Muñoz, Thelma
name: Lakner, Sebastian
name: Brümmer, Bernhard
Publisher: name: Unknown
Year: 2011
Subjects: subject: Farm Management
subject: farm-growth
subject: Gibrat’s law
subject: technical efficiency
subject: direct marketing

description: The organic sector in Germany has experienced a substantial growth since the beginning of the 1990s until today. During this process of expansion, most organic farms have grown in terms of factor endowment, while others have disappeared or reconverted to conventional agriculture. This paper investigates the potential determinants of farms growth in the organic sector. This paper models potential factors that might have an impact on the economic growth of 332 organic farms in Bavaria and Baden-Wuerttemberg. The econometric model was developed based on ‘Gibrat’s Law’, using a fixed effect method (FE). The results suggest that direct marketing and livestock intensity significantly influence farm growth. In addition, less efficient farms grew faster than more efficient ones. This outcome can be explained by the economic pressure on inefficient firms for adaptation during the growth and survival process.
TRT-5-François Berdougo
Creators: name: Leibowitch, Jacques (1942-2020)
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020

description: 1 fichier (6 pages).
Comparison of the performance of two grades of metformin hydrochloride elaboration by means of the SeDeM system, compressibility, compactability, and process capability indices
Creators: name: Hernández, Oswaldo Castañeda
name: Rodríguez, Isidoro Caraballo
name: Bernad, María Josefa Bernad
name: Contreras, Luz María Melgoza
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy

description: Quality by design, applied to the development of a pharmaceutical drug, demands scientific methodologies, representing a source of information that will allow for a complete understanding the production process and the materials used for its manufacturing. Although the SeDeM system is a tool that enables a rational development of a product, result does not assure that an assessed material or mixture will be successful in terms of compression, hence, further research will be necessary on these features. The objective of this study was to assess and compare two grades of metformin hydrochloride elaboration: crystalline and direct compression using PXRD, the SeDeM expert system, the Heckel and Ryshkewitch-Duckworth models, as well as process control tools such as control charts and process capability indices to characterize and predict the performance of the materials in a direct compression process. The assessment identified that in spite of dealing with two different technical grades of a material with specific critical quality attributes for each one, PXRD analysis showed we dealt with the same crystalline structure, while the SeDeM system profiles obtained have very close values, and the main differences in materials were observed when subjecting them to conditions that simulate a compaction process with the Ryshkewitch-Duckworth model, in which a 46-times higher mechanical resistance was observed in the direct compression material compared with the crystalline one. The statistical control analysis revealed that only the direct compression material could be used to elaborate tablets whose weight variation was always maintained within the specification and control limits.
Deriving formulations for numerical computation of binary neutron stars in quasicircular orbits
Creators: name: Shibata, Masaru
name: Uryu, Koji
name: Friedman, John L.
Publisher: name: arXiv
Year: 2004
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: Two relations, the virial relation $M_{\rm ADM}=M_{\rm K}$ and the first law in the form $δM_{\rm ADM}=ΩδJ$, should be satisfied by a solution and a sequence of solutions describing binary compact objects in quasiequilibrium circular orbits. Here, $M_{\rm ADM}$, $M_{\rm K}$, $J$, and $Ω$ are the ADM mass, Komar mass, angular momentum, and orbital angular velocity, respectively. $δ$ denotes an Eulerian variation. These two conditions restrict the allowed formulations that we may adopt. First, we derive relations between $M_{\rm ADM}$ and $M_{\rm K}$ and between $δM_{\rm ADM}$ and $ΩδJ$ for general asymptotically flat spacetimes. Then, to obtain solutions that satisfy the virial relation and sequences of solutions that satisfy the first law at least approximately, we propose a formulation for computation of quasiequilibrium binary neutron stars in general relativity. In contrast to previous approaches in which a part of the Einstein equation is solved, in the new formulation, the full Einstein equation is solved with maximal slicing and in a transverse gauge for the conformal three-metric. Helical symmetry is imposed in the near zone, while in the distant zone, a waveless condition is assumed. We expect the solutions obtained in this formulation to be excellent quasiequilibria as well as initial data for numerical simulations of binary neutron star mergers.
description: to be published in Phys. Rev. D
Neutron diffraction study of average and local structure in La0.5Ca0.5MnO3
Creators: name: Rodriguez, E. E.
name: Proffen, Th.
name: Llobet, A.
name: Rhyne, J. J.
name: Mitchell, J. F.
Publisher: name: arXiv
Year: 2004
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We used neutron powder diffraction to obtain the local and long-range structure of La0.5Ca0.5MnO3 at room temperature and 20K. By combining Rietveld and pair distribution function analysis of the total neutron scattering data, we have analyzed the structure of the compound using two competing models describing the low temperature phase: first the charge ordered/orbital ordered model and second the Mn-Mn dimer model. These structural models fit the 20K neutron powder diffraction pattern equally well using Rietveld analysis. Therefore, pair distribution function analysis is used to probe the local and medium-range structure revealing a system with two distinctly distorted Mn octahedra and Mn ions with non-integral valence states. The distorted octahedra differ with the structural model for the Zener polaron type Mn-Mn dimer picture proposed for Pr0.6Ca0.4MnO3 and order in a similar checkerboard configuration associated with the CE-type anti-ferromagnetic structure. Therefore, locally the charge difference and structural ordering between the two Mn is appreciable enough to describe the system at 20K as "partially charge ordered".
description: 9 pages, 6 figures and 6 tables, to be submitted to Phys. Rev. B
Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: In vitro and in vivo analyses
Creators: name: Sibgha Batool
name: Zahid, Fatima
name: Fakhar-Ud Din
name: Naz, Syeda Sohaila
name: Dar, Muhammad Junaid
name: Khan, Muhammad Waseem
name: Zeb, Alam
name: Khan, Gul Majid
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: The purpose of this study was to develop novel carbopol-based miltefosine-loaded transfersomal gel (HePCTG) for the treatment of cutaneous leishmaniasis (CL) via efficient targeting of leishmania infected macrophages. Miltefosine-loaded transfersomes (HePCT) were prepared by ethanol injection method followed by their incorporation into carbopol gel to form HePCTG. The prepared HePCT were assessed for physicochemical properties including mean particle size, polydispersity index, zeta potential, entrapment efficiency, morphology and deformability. Similarly, HePCTG was evaluated for physiochemical and rheological attributes. The in vitro release, skin permeation, skin irritation, anti-leishmanial activity and in vivo efficacy in BALB/c mice against infected macrophages were also performed for HePCT. The optimized HePCT displayed a particle size of 168 nm with entrapment efficiency of 92%. HePCTG showed suitable viscosity, pH and sustained release of the incorporated drug. Furthermore, HePCT and HePCTG demonstrated higher skin permeation than drug solution. The results of macrophage uptake study indicated improved drug intake by passive diffusion. The lower IC50 value, selectivity index and higher CC50 value of HePCT compared to that of HePC solution demonstrated the improved anti-leishmanial efficacy and non-toxicity of the formulation. This was further confirmed by the notable reduction in parasite load and lesion size observed in in vivo anti-leishmanial study. It can be stated that the formulated HePCTG can effectively be used for the treatment of CL.
Searching for identity: finding the expression of place under-ground
Creators: name: McIntosh, Jacqueline
name: Marques, Bruno
name: Martinez Almoyna Gual, Carlos
name: Campays, Philippe
Publisher: name: Open Access Te Herenga Waka-Victoria University of Wellington
Year: 2024
Subjects: classificationCode: 3301
subject: Architecture
subject: FOS: Civil engineering
classificationCode: 41
subject: Environmental sciences
classificationCode: 410699
subject: Soil sciences not elsewhere classified
classificationCode: 33
subject: Built environment and design
classificationCode: 44
subject: Human society

description: With globalisation and the pressures of climate change, cities are increasingly seeking green solu-tions to urban development. From green roofs to vertical green infrastructure, scholars and built environment practitioners look up to the skies, sun and wind for new ways to develop green technologies. As a result, an emerging technology-led aesthetic is currently developing interna-tionally in architecture and landscape architecture. However, while ubiquitous topsoils support green infrastructure initiatives, the hidden layers of mineral soil and rock that create the unique shape of our landscapes are largely ignored. These mineral soils are relegated to makeup con-struction materials or are buried under concrete and asphalt, leading to the homogenisation of our urban fabric and missing the importance of place and site-specific identity. This research explores the potential of subterranean soil conditions to express regional differences and challenge emerging global trends in soil use. It does this by engaging with the underground and its depth and darkness, delving into the hidden inner world of mineral soils in Aotearoa New Zealand. It finds that the uniqueness and richness of the layers of hidden soil can lead to new ways of understanding place through texture, colour and structure, which in turn can inform aesthetic decisions and develop authentic regional aesthetics.
Global Core Biodata Resources: Webinar for Applicants - February 2022
Creators: name: Drysdale, Rachel
name: Carr, David
name: Cook, Charles E.
Publisher: name: Zenodo
Year: 2022
Subjects: data resource sustainability
bioscience infrastructure
core biodata resources
open data

description: This presentation introduces the Global Biodata Coalition and covers the indicators used for selection, the reasoning for choosing these indicators, and the review process that will define the initial list of the Global Core Biodata Resources. The presentation was given as a series of webinars for potential applicants, delivered between the 22nd and 24th of February, 2022.
ASYMMETRY IN RAW MILK SAFETY PERCEPTIONS AND INFORMATION: IMPLICATIONS FOR RISK IN FRESH PRODUCE MARKETING AND POLICY
Creators: name: Knutson, Ronald D.
name: Currier, Russell W.
name: Ribera, Luis A.
name: Goeringer, L. Paul
name: Knutson, Ronald D.
name: Currier, Russell W.
name: Ribera, Luis A.
name: Goeringer, L. Paul
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: Health Economics and Policy
subject: raw milk
subject: pasteurization
subject: health risks
subject: behavioral economics
subject: bounded rationality
subject: paternalistic regulations
subject: public health
subject: HACCP
subject: GLOBALG.A.P.

description: Scientific evidence clearly indicates that consumption of raw milk carries substantial disease-inducing health risks. While federal U.S. policy mandates that milk moving in interstate commerce be pasteurized; within 41 of 50 states, raw milk can be obtained for consumption. Warning labels notwithstanding, a segment of U.S. consumers pays higher prices for higher-risk raw milk than for either organic or conventional milk. The behavioral factors leading to raw milk consumption are explored. The paternalistic regulatory options for reducing the risk associated with drinking raw milk are identified. Implications for fresh produce sold directly from farms to consumers or through farmers markets are drawn.
Development and characterization of pluronic lecithin organogel containing fluocinolone acetonide
Creators: name: Dinal Patel
name: Viral Patel
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer
subject: Science Policy

description: The rabble-rousing skin condition can be conventionally treated, but due to some demerits, there is a need to find a novel approach with an appropriate release profile. The research work narrates the optimization of the topical delivery system of Fluocinolone acetonide loaded in pluronic lecithin organogel. The preliminary studies were carried out and, the ternary phase diagram was established by Chemix school version 3.60. The formulation was optimized by taking a different concentration of polymers as independent and viscosity and drug release (6 h) as dependent variables by applying 32 full factorial design. The optimized batch was further compared with marketed preparation and also kept for the stability study. The release profile of the optimized batch exhibited a sustained release of up to 6 h (77.00%). It gave ex-vivo drug release up to 6 h (90.64%) which is more prolonged than marketed preparation and, cutaneous disposition was found to be higher. Besides, the texture analysis was compared to that of the marketed formulation of the drug. However, the proof of the effectiveness of the formulated pluronic lecithin organogel will require further in-vivo study for future aspects. In a nutshell, the proposed formulation of fluocinolone acetonide is the simplest and promising dosage form for the treatment of psoriasis.
Jets in Nuclear Collisions: Status and Perspective
Creators: name: Jacobs, Peter
Publisher: name: arXiv
Year: 2005
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: I review the status and future directions of jet-related measurements in high energy nuclear collisions and their application as a probe of QCD matter.
description: Summary talk, Hard Probes 2004, Ericeira, Portugal, Nov. 4-10, 2004; 8 pages, 5 figures; v2 has minor corrections
AN ANALYSIS OF THE RETIREMENT-CONSUMPTION PUZZLE FOR FOOD-AT-HOME AND AWAY-FROM-HOME EXPENDITURES IN GERMANY
Creators: name: Drescher, Larissa S.
name: Roosen, Jutta
name: Drescher, Larissa S.
name: Roosen, Jutta
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: Health Economics and Policy
subject: cohort analysis
subject: retirement-consumption puzzle
subject: food-at-home expenditures
subject: food-away- from-home expenditures
subject: Germany

description: According to Ando and Modigliani (1957), consumers pass different stages of a lifecycle with different impact on demand. The criticism that the life-cycle theory neglects generational effects and concentrates on ageing effects only has led to the application of the cohort analysis which decomposes not only age, but also period and cohort effects. Following these ideas, this paper presents results of a cohort analysis on food-at-home and away-from-home consumption covering 25 years of German consumption data. Special attention is given to the retirement-consumption puzzle which is the unanticipated drop in consumption after retirement. Results of seemingly unrelated regressions indicate that there are significant age, period and cohort effects of food-at-home and away-from-home expenditures which are more distinct for at-home consumption. Among others, pensioners appear to have significantly lower expenditures for food-at-home and food-away-from-home than non-retired households which points towards the existence of a retirement-consumption puzzle for these two consumption groups.
AGEING AND CONSUMPTION – THE IMPACT OF DEMOGRAPHIC CHANGE ON FOOD EXPENDITURE PATTERNS
Creators: name: Anders, Sven M.
name: Anders, Sven M.
Publisher: name: Unknown
Year: 2010
Subjects: subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Food Consumption/Nutrition/Food Safety
subject: Food Security and Poverty
subject: Health Economics and Policy
subject: Life-cycle hypothesis
subject: Retirement consumption puzzle
subject: food expenditure
subject: Canada

description: Populations in most developed countries are ageing while fertility is declining. Policy makers and researchers expect this demographic shift to induce major shifts in most Western societies, economies and public policies. Moreover, changing requirements, demands and public health pressures (e.g. diabetes) of ageing populations are expected are likely to alter food expenditure patterns for various goods categories, including food products. The objective of this paper is to investigate to what extent household's food expenditure patterns shift around retirement age and what role changes in time use spend on home production play in this context. More specifically this paper reviews literature relevant to economic literature that has evolved around Modigliani and Brumberg's (1954) economic life-cycle hypothesis (LCH) based on the model of inter-temporal choice. Analysis of expenditure patterns using a recent sample of Canadian household-level scanner data reveal significant differences in meat product expenditure patterns and preferences between consumers of different age cohorts.
Development and validation of the quantitation of S.P.E.C.T. images for clinical applications
Creators: name: Dixon, Katherine Louise
Publisher: name: University of British Columbia
Year: 2009

description: The obtaining of accurate quantitative information is essential to the future development of nuclear medicine. This thesis uses three clinical quantitative measurements: tumour dosimetry, myocardial wall thickness, and myocardial infarct size, to show that accurate quantitative diagnostic information can be extracted from nuclear medicine studies. Additionally, this thesis determines the importance of comprehensive corrections for photon attenuation, photon scatter and distance-dependent resolution loss in the production of this quantitative information. Dosimetry and myocardial perfusion data sets were acquired from computer simulations, physical phantoms and clinical patients. Each data set was reconstructed using (1) filtered back-projection (FBP), (2) ordered-subset expectation maximization (OSEM), (3) OSEM plus attenuation correction (AC), (4) OSEM plus detector response compensation (DRC), (5) OSEM plus AC and DRC, and (6) OSEM plus AC, DRC and scatter correction (SC). iQuant software was developed to affectively evaluate the biodistribution of activity required for dosimetry calculations, myocardial wall thickness and myocardial infarct size. iQuant measures infarct size with exceptional accuracy and reliability, and its advantages over other myocardial quantitation software include its 3-dimensional analysis that does not require the creation of polar maps or normal heart databases. The inclusion of AC in the reconstruction process significantly improved the accuracy of tumour activity estimates (by 30%) and myocardial infarct sizes in both the inferior and septal myocardial walls (by 1% of the total myocardial volume). The inclusion of DRC produced a myocardial wall thickness closer to the truth (by 25%). AC and DRC are therefore essential for an accurate diagnostic assessment of myocardial perfusion studies and dosimetry. The addition of SC improved the accuracy of tumour activity estimates, particularly in regions with non-uniform attenuation properties (to within 5% of the truth for tumors greater than 5ml). it also provided myocardial wall thickness values closer to the truth than any other technique (10% closer than OSEM+DRC), and improved the accuracy and precision of myocardial infarct sizes (to within 0.75% of the total myocardial volume). The application of SC in addition to AC and DRC is therefore indicated in research studies involving dosimetry or myocardial infarct size, where the accuracy of measurement is essential.