cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Data for individual hominin fossil skulls from Correction to ‘Fossil skulls reveal that blood flow rate to the brain increased faster than brain volume during human evolution’
Creators: name: Seymour, Roger S.
name: Bosiocic, Vanya
name: Snelling, Edward P.
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: 40308 Palaeontology (incl. Palynology)
subject: FOS: Earth and related environmental sciences

description: Revised list of individual fossil specimens used for analysis of internal carotid artery size and blood flow rate. Sources of the data are indicated.
Latent Profiles of Organizational, Occupational and Supervisor Commitment among Nurses and their Effects on Employee Well-being and Health
Creators: name: Wombacher, Jörg
name: Konrad, Jonas
name: Raff, Tilmann
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2019
Subjects: subject: Commitment
subject: Latent Profiles
subject: Health
subject: Stress
subject: Nursing
subject: FOS: Health sciences

description: Purpose Demographic changes have led to a shortage of nurses in the healthcare sector. Nursing staff and patients are getting older and nursing cases are becoming increasingly complex. As a result, nurses’ workloads and stress levels have increased, and employee turnover has risen. Adopting a person-centered perspective, this study examines the effects of nurses’ commitment profiles on their physical and emotional well-beingand other work-related outcomes. The profiles will will be extracted based on nurses’ affective, rational, and normative commitment to their organization, occupation, and supervisor. Design and Methodology A survey was conducted among 1029 nurses from all public hospitals, nursing homes and outpatient care services from the Swiss Canton of Solothurn. A latent profile analysis using Mplus was performed to extract the commtiment profiles and examine their associations with the outcome variables. Results Four commitment profiles were found that differ both quantitatively (in terms of commitment levels) and qualitatively (in terms of shape). Results show, among others, that nurses with a high affective but low rational and normative commitment to all three foci (occupation, organization, supervisor) show higher levels of emotional strain than other profiles (e.g., low commitment levels) but also greater levels of work-life-balance and health. Limitations The cross-sectional nature of the survey precludes causal inferences. Because all data were self-reported, the associations found between profiles and outcomes may be inflated. Implications for research The person-centered approach allows an examination of complex interaction patterns among commitment foci and dimensions and their associations with work-related outcomes. A longitudinalstudy is in order to better understand causal directions and the development of complex commitment profiles over time. Practical implications The study results are relevant to practices in human resource management and retention in the healthcare sector. Because the commitment profiles refer to a broad, within-person observation of nurses, it is important to address the whole individual in interventions targeted at the improvement of unbeneficial commitment profiles. A strict focus on single commitment foci or dimensions may not be enough. Orginality, Value To our knowledge, this is the first comprehensive exploration of complex commitment profiles and their association with employee health and well-being in the nursing profession.
title: ADCO, Cartulaire de Cîteaux pour le prieuré de Gilly : rachat de la rente due à Saint-Germain-des-Prés (c. 1501), Cart. 194 (11 H 636), 64 folios, f. 0043
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2015
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire de Cîteaux pour le prieuré de Gilly : rachat de la rente due à Saint-Germain-des-Prés (c. 1501), Archives départementales de la Côte-d'Or, Cart. 194 (11 H 636), 64 folios, f. 0043, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour le prieuré de Gilly : rachat de la rente due à Saint-Germain-des-Prés (c. 1501), Archives départementales de la Côte-d'Or, Cart. 194 (11 H 636), 64 folios, f. 0043, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
O'ZBEKISTONDA BUDJETLARARO MUNOSABATLARNI TAKOMILLASHTIRISH MASALALARI
Creators: name: Asqarova, Aziza
Publisher: name: Zenodo
Year: 2025

description: O‘zbekistonning iqtisodiy rivojlanishiga ko‘maklashish maqsadida, byudjetlararo munosabatlar doimiy ravishda takomillashib boradi va yangi tizimlar joriy etilmoqda. Bu munosabatlar, ayniqsa, mintaqalararo ijtimoiy farovonlikni ta'minlashda muhim ahamiyat kasb etadi. Byudjetlararo munosabatlar — bu turli darajadagi davlat organlari (markaziy va mahalliy boshqaruv organlari) o‘rtasidagi moliyaviy resurslarni taqsimlash va ularning sarflanishini boshqarish tizimidir. O‘zbekiston kabi davlatlarda bu munosabatlar, asosan, davlatning iqtisodiy siyosatiga muvofiq byudjet mablag‘larini samarali taqsimlash, iqtisodiy adolatni ta'minlash va hududlar o‘rtasidagi farqni kamaytirish maqsadida tashkil etiladi. Byudjetlararo munosabatlarning asosiy elementlari. Taqsimlash va resurslarni ajratish: Byudjetlararo munosabatlarda markaziy va mahalliy byudjetlar o‘rtasida resurslar taqsimlanadi. Markaziy hukumat o‘zining umumiy moliyaviy resurslarini mahalliy hududlarga taqsimlaydi. Bu jarayonning asosiy maqsadi hududlar o‘rtasidagi iqtisodiy tafovutlarni kamaytirish va barcha hududlarda ijtimoiy xizmatlarning sifatini ta'minlashdir.
A new paradigm for the continuous alignment of business and IT: combining enterprise architecture modelling and enterprise ontology
Creators: name: Hinkelmann, Knut
name: Gerber, Aurona
name: Karagiannis, Dimitris
name: Thönssen, Barbara
name: Van Der Merwe, Alta
name: Woitsch, Robert
Publisher: name: Elsevier
Year: 2016
Subjects: subject: Business and IT alignment
subject: Enterprise Engineering
subject: Enterprise Architecture
subject: Enterprise Ontology
subject: 330 - Wirtschaft
subject: 000 - Computer science, information & general works
subject: 001 - Knowledge

description: The paper deals with Next Generation Enterprise Information Systems in the context of Enterprise Engineering. The continuous alignment of business and IT in a rapidly changing environment is a grand challenge for today’s enterprises. The ability to react timeously to continuous and unexpected change is called agility and is an essential quality of the modern enterprise. Being agile has consequences for the engineering of enterprises and enterprise information systems. In this paper a new paradigm for next generation enterprise information systems is proposed, which shifts the development approach of model-driven engineering to continuous alignment of business and IT for the agile enterprise. It is based on a metamodelling approach, which supports both human-interpretable graphical enterprise architecture and machine-interpretable enterprise ontologies. Furthermore, next generation enterprise information systems are described, which embed modelling tools and algorithms for model analysis.
title: H επιρροή των influencers στην αθλητική βιομηχανία και μελέτη περίπτωσης εν μέσω πανδημίας Covid-19
title: Impact of Influencers on the Sport Industry: COVID-19 Pandemic Case Study
titleType: AlternativeTitle
Creators: name: Κρανιά, Αγγελική
Publisher: name: Πανεπιστήμιο Πελοποννήσου
Year: 2022
Subjects: subject: Πανδημίες και COVID-19
subject: Αθλητισμός - Μάρκετινγκ
subject: Μέσα μαζικής ενημέρωσης και αθλητισμός
subject: Επικοινωνία στο μάρκετινγκ
subject: Επικοινωνία στον αθλητισμό
subject: Αθλητισμός, εμπόριο και πολιτισμός
subject: Pandemics and COVID-19
subject: Sports - Marketing
subject: Mass media and sports
subject: Communication in marketing
subject: Communication in sports
subject: Sport, commerce and culture
subject: Pandemic COVID-19
subject: Sport industry
subject: Influencer
subject: Marketing
subject: FOS: Economics and business
subject: Πανδημία COVID-19
subject: Αθλητισμός
subject: Μαρκετινγκ
subject: Ιnfluencers

description: O σκοπός της παρούσας εργασίας είναι να παραθέσει και να αναλύσει την επιρροή που ασκούν οι influencers στην αθλητική βιομηχανία και συγκεκριμένα εν μέσω μιας πανδημίας. Ο κορωνοϊός COVID-19 επηρέασε την αθλητική βιομηχανία επιβάλλοντας το κλείσιμο των πρωταθλημάτων και αναβολή εκδηλώσεων όπως οι Ολυμπιακοί αγώνες στο Τόκιο. Ωστόσο, οι νέες τεχνολογίες μέσων, έχουν προσφέρει μια ευκαιρία σε αθλητικούς οργανισμούς και αθλητές να συνεχίσουν να αλληλοεπιδρούν με τους καταναλωτές τους και να προωθούν τη σωματική δραστηριότητα κατά την απουσία ζωντανών αθλημάτων. Οι νέες τεχνολογίες μέσων επιτρέπουν σε οργανισμούς και άτομα να μοιραστούν αθλητικό υλικό που δημιουργείται από τους ίδιους τους χρήστες χρησιμοποιώντας την διαδραστικότητα που προσφέρουν οι νέες τεχνολογίες. Η τωρινή κατάσταση (εν μέσω πανδημίας) έχει εγείρει τη συζήτηση, το ενδιαφέρον και την έρευνα εάν τα κοινωνικά μέσα θα μπορούσαν να χρησιμοποιηθούν ως πλατφόρμα για να εμπνεύσουν τη σωματική δραστηριότητα και αθλητική συμμετοχή και ποιες στρατηγικές μπορεί να είναι επιτυχημένες στους καταναλωτές. Οι influencers δηλαδή οι ηγέτες γνώμης παίζουν το πιο σημαντικό ρόλο και το μάρκετινγκ που χρησιμοποιούν έχει πολλά πλεονεκτήματα και δυνατότητες. Η πανδημία COVID-19 θα μπορούσε να μεταμορφώσει ολικά τον τρόπο λειτουργίας του αθλητισμού στο μέλλον. την παρούσα μελέτη ερωτήθηκαν 256 άτομα μέσω ερωτηματολογίου που αφορούσε την ανάπτυξη του influencer marketing συνολικά αλλά και συγκεκριμένα εν μέσω αυτής της πανδημίας. Τα αποτελέσματα από την έρευνα του συγκεκριμένου συνόλου υπέδειξαν ότι οι influencers επηρεάζουν και κερδίζουν έδαφος στην αθλητική βιομηχανία. Όμως παρόλη την επιρροή που ασκούν δεν παύουν να θεωρούνται ερασιτέχνες.
PVopti - hourly based energy balance for building design
Creators: name: Hall, Monika
name: Burger, Bastian
Publisher: name: Elsevier
Year: 2017
Subjects: self-consumption
hourly bases energy balance
tool
building design
electric storage
autarky

description: PVopti is a freeware tool to calculate hourly energy balance for different building types. It is simple to use and it quickly calculates self-consumption for different designs. Load profiles according to SIA 2024 are used to distribute yearly values on hours. For demand of lighting a criterion for daylight is added. Compared with measurements of single family houses and apartment buildings, self-consumption calculated with PVopti shows very good agreement. Currently, a German version is available on www.minergie.ch, soon there will be versions for 4 languages (dt, fr, it, en).
Additional file 4: of Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults
Creators: name: Dye, Christian
name: Corley, Michael
name: Li, Dongmei
name: Khadka, Vedbar
name: Mitchell, Brooks
name: Sultana, Razvan
name: Lum-Jones, Annette
name: Shikuma, Cecilia
name: Ndhlovu, Lishomwa
name: Maunakea, Alika
Publisher: name: figshare
Year: 2019
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Figure S4. Differentially methylated loci from HIV-seronegative individuals stratified by HOMA-IR into IR or IS. A. Workflow for processing DNA methylation data acquired from 450k microarray to generate the HIV-seronegative DML of IR. B. Unsupervised hierarchal clustering heatmap using Manhattan distance, complete linkage method displays DNA methylation (Î˛ value) of the 304 CpGs of the HIV-seronegative DML of IR, stratifies IS individuals (green) from IR individuals (purple). DNA methylation ranges from low (0, blue) to intermediate (.50, yellow), to high (1.0, red). C. Vendiagram is representative of the two datasets that culminate the DML of IR in HIV-infected individuals (left; DML of IR) and HIV-seronegative individuals (right; HIV-seronegative DML of IR). Shown are the CpG counts that are independent to each dataset and the CpGs that are overlapped in both datasets; below displays the number of genes harbored at the CpGs. D. Comparison of monocyte subset-specific DNA methylation correlation of HIV-seronegative IR and IS individuals. Correlation determined utilizing Spearmanâ s rho (r); significance determined using Mann-Whitney U test between IS and IR at P < 0.05. (PDF 9233 kb)
title: Ανάλυση, μοντελοποίηση και πρόγνωση του δείκτη ναυλαγοράς Baltic Dry Index (BDI) με χρήση machine learning αλγορίθμων και νευρωνικών δικτύων
title: Analysis, modeling and forecasting of the Baltic Dry Index (BDI) using machine learning algorithms and neural networks
titleType: AlternativeTitle
Creators: name: Κουτσούκος, Δημήτριος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2022
Subjects: subject: Πρόγνωση χρονοσειρών
subject: Δείκτης ναυλαγοράς BDI
subject: Νευρωνικά δίκτυα
subject: Μηχανική μάθηση

description: Στα πλαίσια της παρούσας διπλωματικής εργασίας πραγματοποιείται βιβλιογραφική ανασκόπηση ερευνών οι οποίες χρησιμοποιούν αλγορίθμους μηχανικής μάθησης και νευρωνικά δίκτυα με σκοπό την πρόβλεψη του χρηματιστηριακού δείκτη Baltic Dry Index (BDI). Οι έρευνες αυτές θα κατηγοριοποιηθούν ανάλογα τον τρόπο μοντελοποίησης και πρόβλεψης που χρησιμοποιούν. Επίσης θα γίνει εκτενής αναφορά στον τρόπο με τον οποίο λειτουργεί το σύστημα της μεταφοράς χύδην ξηρού φορτίου και στους παράγοντες από τους οποίους επηρεάζεται ο δείκτης ναυλαγοράς και κατά συνέπεια και η τιμή των ναύλων, με στόχο την κατανόηση των συσχετίσεων που υπάρχουν στο σύστημα και επομένως τον καθορισμό του τρόπου δόμησης του μοντέλου που θα δημιουργηθεί για την πρόβλεψη του δείκτη. Επιπροσθέτως θα αναλυθεί ο τρόπος λειτουργείας των αλγορίθμων μηχανικής μάθησης οι οποίοι χρησιμοποιούνται στην βιβλιογραφία για πρόβλεψη του δείκτη με σκοπό την εύρεση των αλγορίθμων οι οποίοι προσαρμόζονται καλύτερα στις ιδιαιτερότητες του χρηματιστηριακού δείκτη. Θα αναλυθεί ο τρόπος με τον οποίο θα γίνει η συλλογή, η προεπεξεργασία και η μοντελοποίησης των δεδομένων με σκοπό την χρήση τους στους κατάλληλους αλγορίθμους μηχανικής μάθησης. Στην συνέχεια θα πραγματοποιηθεί μονομεταβλητή και πολυμεταβλητή ανάλυση (Univariate / Multivariate analysis) με σκοπό να εξεταστεί αν κάποια από τις δύο προσεγγίσεις παράγει ακριβέστερο μοντέλο πρόβλεψης του δείκτη ναυλαγοράς BDI. Τέλος θα γίνει σύγκριση των πιο αποτελεσματικών μοντέλων για κάθε μία από τις μεθόδους ανάλυσης ενώ θα επιχειρηθεί βελτίωση του μοντέλου πρόβλεψης του δείκτη, δοκιμάζοντας τον συνδυασμό των μοντέλων που επιτυγχάνουν βέλτιστη πρόβλεψη.
ESM file from Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity
Creators: name: Paschalis, Vasileios
name: Chatelier, Emmanuelle Le
name: Green, Matthew
name: Képès, François
name: Soultanas, Panos
name: Janniere, Laurent
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology

description: During Bacillus subtilis replication two replicative polymerases function at the replisome to collectively carry out genome replication. In a reconstituted in vitro replication assay, PolC is the main polymerase while the lagging strand DnaE polymerase briefly extends RNA primers synthesized by the primase DnaG prior to handing-off DNA synthesis to PolC. Here, we show in vivo that (i) the polymerase activity of DnaE is essential for both the initiation and elongation stages of DNA replication, (ii) its error rate varies inversely with PolC concentration and that (iii) its misincorporations are corrected by the mismatch repair system post-replication. We also found that the error rates in cells encoding mutator forms of both PolC and DnaE are significantly higher (up to 15-fold) than in PolC mutants. In vitro, we showed that (i) the polymerase activity of DnaE is considerably stimulated by DnaN, SSB and PolC, (ii) its error-prone activity is strongly inhibited by DnaN and that (iii) its errors are proofread by the 3′ > 5′ exonuclease activity of PolC in a stable template-DnaE–PolC complex. Collectively our data show that protein–protein interactions within the replisome modulate the activity and fidelity of DnaE and confirm the prominent role of DnaE during B. subtilis replication.
Einsatz von digitalen Medien an der Berufsschule Aarau
Creators: name: Frey, Madeleine
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2018

description: Das Ziel dieser Arbeit ist, das Erleben des Einsatzes von digitalen Medien an der Berufsschule Aarau seitens der Lehrpersonen zu erfassen. Die gewonnenen Erkenntnisse sollen der Berufsschule Aarau zu einem praxisgerechten und von allen Lehrpersonen akzeptierten Einsatz von digitalen Medien im Unterricht dienen. Der Einsatz von digitalen Medien wird seitens der Lehrpersonen sehr geschätzt. Der Unterricht ist mit dem Einzug von digitaler Medien flexibler, spontaner und aktueller geworden. Allerdings sollten sie nur in Kombination mit anderen Medien und Unterrichtsformen eingesetzt werden. Eine Zusatzausbildung bezüglich digitaler Medien würde für die Lehrpersonen eine Erleichterung darstellen. Alle Lehrpersonen sollten an einem Strang ziehen und dieselbe Software, dieselben Apps oder Tools verwenden und Erkenntnisse aus dem täglichen Gebrauch teilen. Den Lehrpersonen ist klar, dass mit dem Einsatz von digitalen Medien eine Veränderung im Schulsystem stattfinden wird und der Einsatz digitaler Medien sowie die Wahl der Mittel und Plattformen sehr gut geplant werden muss.
title: ADCO, Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Cart. 181 (11 H 754), 165 folios, f. 0195
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2017
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge

description: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0195, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les possessions de Chaugey et Maison-Dieu (Fin XVe siècle), Archives départementales de la Côte-d'Or, Cart. 181 (11 H 754), 165 folios, f. 0195, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Erfolgreiche Ansprache und Gewinnung von medizinischen Fachkräften im Bereich Pflege
Creators: name: Vogel, Michelle
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2020

description: Der Pflegefachkräftemangel ist eine globale Herausforderung. Auch in Zukunft wird es schwierig sein, die offenen Stellen mit qualifizierten Pflegenden zu besetzen. Somit besteht die Notwendigkeit für Gesundheitsinstitutionen, Personalmarketingmassnahmen zu ergreifen, um als attraktiver Arbeitgeber dazustehen und aktiv auf potenzielle Bewerbende zuzugehen. Vom Fachkräftemangel betroffen ist auch das Schweizer Paraplegiker-Zentrum (SPZ). Das Berufsfeld der Pflege wird in der vorliegenden Arbeit beschrieben und folgend auf Personalmarketingmassnahmen in Bezug auf Employer Branding und Active Sourcing eingegangen. Mittels Experteninterviews und halbstandardisierten Interviews wurden Erhebungen zum Fachkräftemangel und zu möglichen Personalmarketingmassnahmen für das SPZ gemacht. Es werden Handlungsempfehlungen für das SPZ abgeleitet. Die Employer Brand könnte das SPZ beispielsweise optimieren, indem Werbung gemacht wird für das SPZ als Arbeitgeber und somit der Bekanntheitsgrad in der Schweiz erhöht wird. Eine Active Sourcing Möglichkeit wäre, dass das SPZ in Zukunft für potenzielle Bewerbende Events oder Schnuppertage im Unternehmen anbietet.
Additional file 8 of CCCH Zinc finger genes in Barley: genome-wide identification, evolution, expression and haplotype analysis
Creators: name: Ai, Qi
name: Pan, Wenqiu
name: Zeng, Yan
name: Li, Yihan
name: Cui, Licao
Publisher: name: figshare
Year: 2022
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8.
Nonverbal behavior of interviewers influences the competence ratings of observers in recruitment interviews: a study investigating social influence using 360‑degree videos with virtual reality and 2D screen displays
Creators: name: Wyssenbach, Thomas
name: Zeballos, Melina
name: Loosli, Stefan
name: Schwaninger, Adrian
Publisher: name: Springer
Year: 2022
Subjects: Virtual Reality
360-degree video
Social influence
Nonverbal behavior
Immersion
Job recruitment interview

description: This study examined whether an interviewer’s nonverbal behavior influences observers’ competence ratings in a recruitment interview using 360-degree videos experienced with immersive virtual reality (VR-cardboard) and 2D screen displays. Participants (n = 110) observed a recruitment interview and assessed three competences of the applicant (behavior in a team, customer care, and sales skill). We used a 2 × 2 design with the nonverbal behavior (positive vs. negative) of the interviewer and display type (VR-cardboard vs. 2D screen display) as between-subjects factors. After observing interview sequences and providing competence ratings, participants also rated different aspects of immersion using the augmented reality immersion questionnaire (ARI; Georgiou and Kyza in Int J Hum Comput Stud 98: 24–37, 2017) and their overall satisfaction with the experience. For two of the three competences (customer care and behavior in a team), we found that observers gave higher competence ratings when the interviewer’s nonverbal behavior was positive compared to when it was negative. This social influence effect was similar for 360-degree videos experienced with immersive VR and 2D screen displays. VR resulted in higher immersion than 2D screen displays regarding the dimensions of flow and presence. Our results suggest that the ARI questionnaire can be used to reliably assess 360-degree videos experienced with immersive VR and 2D screen displays.
NanoFrazor Scholar – hochauflösendes Nanolithographie-Tool für Technologie Einsteiger
Creators: name: Erne, Robin
name: Sekler, Jörg
name: Berta, Marco
Publisher: name: Hochschule für Technik FHNW
Year: 2017
Subjects: Regelungstechnik
Nanolithographie

description: Im Rahmen eines KTI-Projektes wird zusammen mit der Firma SwissLitho ein neues Instrument zur Nanometer-genauen Oberflächenbearbeitung entwickelt. Die Neuentwicklung soll den Zugang zu einem erweiterten Markt und zu einzelnen Forschungsgruppen ermöglichen. Zudem werden die bereits bestehenden, grösseren Systeme durch die neuen Erkenntnisse verbessert.
Kp determination by derivative spectroscopy and Stern Volmer plots of Daunorubicin using a DMPC:SM model system. from A biophysical approach to daunorubicin interaction with model membranes: relevance for the drug's biological activity
Creators: name: Alves, Ana Catarina
name: Ribeiro, Daniela
name: Horta, Miguel
name: Lima, José L. F. C.
name: Nunes, Cláudia
name: Salette Reis
Publisher: name: The Royal Society
Year: 2017
Subjects: subject: Biophysics
subject: 90301 Biomaterials
subject: FOS: Medical engineering
subject: 30402 Biomolecular Modelling and Design
subject: FOS: Chemical sciences

description: Absorption (A) and third-derivative absorption (B) spectra of daunorubicin (40μM) (red line, 0) alone, incubated in DMPC:SM model membrane at 37 °C. Stern–Volmer plots of the probe DPH in the DMPC:SM model at pH 7.4 and 37 °C with increasing daunorubicin concentrations
title: ADCO, Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Cart. 172 (11 H 69), 115 folios, f. 0172
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0172, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'office de la Porte de l'abbaye de Cîteaux, Registrum possessionum porte Cistercii (début XVe siècle), Archives départementales de la Côte-d'Or, Cart. 172 (11 H 69), 115 folios, f. 0172, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
title: ADCO, Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Cart. 168 (11 H 66), f. 0175v
Creators: name: de la Côte d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2010
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0175v, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de l'abbaye de Cîteaux dit Cartulare Antiquum t.3 (2e moitié XIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 168 (11 H 66), f. 0175v, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Track 1 Lightning Talk: Research Software in Brazil
Creators: name: Silva, Raniere
Publisher: name: figshare
Year: 2017
Subjects: subject: 80399 Computer Software not elsewhere classified
subject: FOS: Computer and information sciences

description: In 2014, a survey in the UK showed how important research software is. On this paper, the author compares the data from the 2014 survey on the UK with new data from Brazil to discover that a quarter of Brazilian academics develop their own software as part of their work but never had training on software development.
title: Supercritical carbon dioxide as a carrier for sample introduction in atomic absorption spectrometry
Creators: name: Bysouth, S. R.
name: Tyson, Julian
Publisher: name: University of Massachusetts Amherst
Year: 1992
Subjects: subject: Atomic absorption spectrometry
subject: Carbon dioxide
subject: Carriers
subject: Sample introduction
subject: Supercritical carbon dioxide
subject: Analytical Chemistry
subject: FOS: Chemical sciences
subject: Chemistry

description: The use of a supercritical carbon dioxide carrier to transport organic solutions of metal complexes to a heated restrictor is demonstrated as a means of aerosol or vapour generation for sample introduction in flame atomic absorption spectrometry. Calibrations obtained using conventional pneumatic nebulisation of continuously aspirated solutions or using flow injection into a water carrier are compared with those obtained using the carbon dioxide carrier. Injection of solutions of copper pyrrolidinedithiocarbamate in 4-methyl pentan-2-one into a carbon dioxide carrier at 1000 p.s.i. was shown to be 1.2 times more sensitive than injection of the same solutions into a water carrier with conventional nebulisation. The sensitivity of continuous nebulisation of the solutions, however, was not achieved. Dissolution of solid copper acetyl acetonate in supercritical carbon dioxide is demonstrated and subsequent vaporisation followed by atomisation in a heated quartz furnace is shown to occur.
Coordination polymers and discrete complexes of Ag(I)-N-(pyridylmethylene)anilines: synthesis, crystal structures and photophysical properties
Creators: name: Njogu, Eric M.
name: Omondi, Bernard
name: Nyamori, Vincent O.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Reactions of AgO2C2F3 with (E)-N-(pyridylmethylene)aniline in which the pyridyl N is in the p- or m-position yielded two 1-D coordination polymers, [(AgO2C2F3)2(La)2]n (La = (E)-2,6-diisopropyl-N-(pyrid-3-ylmethylene)aniline) (1) and [(AgOC2F3)2(Ld)2]n (Ld = (E)-2,6-diisopropyl-N-(pyrid-4-ylmethylene)aniline) (5), and three discrete complexes, [(AgO2C2F3)2(La)4] (2), [AgO2C2F3(Lb)2] (Lb = (E)-N-(pyrid-4-ylmethylene)aniline) (3) and [(AgOC2F3)2(Lc)4] (Lc = (E)-2,6-dimethyl-N-(pyrid-4-ylmethylene)aniline) (4). The structures were determined by MS, FT-IR and NMR spectroscopies, elemental analysis and single crystal XRD. 1 is an organometallic coordination polymer with silver in η1-arene coordination, but is a discrete dimeric complex 2 when crystallized from warm diethylether. The geometries around silver(I) in 1 and 4 are tetrahedral, ‘inverted seesaw’ in 2 and T-shaped in 3 and in all the anion seems to play a role. Ag(I) centers in 5 have distorted trigonal bipyramid and inverted seesaw geometries. The trifluoroacetate anions in these complexes display variable monodentate and short bridging coordination patterns. All complexes absorb and strongly emit UV-Vis radiation at room temperature.
GreenCharge Project Deliverable: D2.18 Pilot Component Preparation for Full-scale Pilot (Barcelona)
Creators: name: Freixas, Lluís
name: Enrich, Regina
name: León, Alberto
name: López, Baltasar
Publisher: name: Zenodo
Year: 2019
Subjects: eMobility
Charging management
Smart energy management
EV fleet management

description: This deliverable presents the components that are going to be integrated in the full-scale implementation for the Barcelona pilot. The needed components and their role in the pilot have been extracted from work presented on deliverables D2.16 Description of Barcelona Pilot and User Needs and D2.17 Implementation Plan for Barcelona Pilot. The table below lists all the components. It indicates for each component the demonstrators in which it will be used (there are three demonstrator sites). It also indicates the “Test result” for each component as follows: New development (RED). The component does not yet exist and needs to be developed from scratch in the course of the project. Needs adaptation (YELLOW). Testing of the component has been carried out and identified that some adaptations are needed for successful use in the pilot. Approved (GREEN). The component has been tested and found to be suitable for full-scale implementation in the pilot; some work may be needed to integrate fully with other components. Sub-system role Component name Demonstrator Test result Responsible partner EV In-vehicle system Atlantis Fleet app e-bike sharing New development ATLANTIS IT EV In-vehicle system Scooter shared services app MOTIT Needs adaptation MOTIT EV In-vehicle system Journey planner app Eurecat, e- bike sharing Needs adaptation EURECAT EV In-vehicle system Data logger and GPS tracker devices e-bike sharing Approved ATLANTIS IT Fleet management system Atlantis Fleet platform e-bike sharing Needs adaptation ATLANTIS IT Fleet management system Scooter shared services fleet managemen MOTIT Approved MOTIT Charge management system (CMS) Algorithm for vehicle autonomy calculation Eurecat Needs adaptation EURECAT Charge management system (CMS) Battery swapping in hub MOTIT Approved MOTIT Charge management system (CMS) Charging point (Eurecat) Eurecat Needs adaptation EURECAT Charge management system (CMS) Charging point (St. Quirze) e-bike sharing Needs adaptation MILLOR ENERGY Charge management system (CMS) Booking system Eurecat New development EURECAT Charge management system (CMS) Charge management system All New development EURECAT Neighbourhood energy management system (NEMS) SEM forecaster All Needs adaptation EURECAT Neighbourhood energy management system (NEMS) SEM forecaster All Needs adaptation EURECAT Neighbourhood energy management system (NEMS) PV panels Eurecat Approved EURECAT Neighbourhood energy management system (NEMS) PV panels e-bike sharing Approved MILLOR ENERGY Local battery storage Stationary battery e-bike sharing Needs adaptation MILLOR ENERGY
Additional file 5: of Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults
Creators: name: Dye, Christian
name: Corley, Michael
name: Li, Dongmei
name: Khadka, Vedbar
name: Mitchell, Brooks
name: Sultana, Razvan
name: Lum-Jones, Annette
name: Shikuma, Cecilia
name: Ndhlovu, Lishomwa
name: Maunakea, Alika
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: Table S3. Clinical characteristics of HIV-seronegative individuals stratified by insulin sensitivity and insulin resistance. Table represents clinical data comparing the IS and IR groups of HIV-seronegative individuals. Data shown are median values [first quartile, third quartile]. P value determined between IS and IR groups using Mann-Whitney U test; significance at P < 0.05. (PDF 9233 kb)
EYES ON THE STREET: A REAL-TIME REPORTING APP FOR IMPROVED PUBLIC SAFETY
Creators: name: OKECHUKWU, Ogochukwu P
name: OKECHUKWU, Godson N
name: EZURUKA, Evelyn O
name: IDUH, Blessing N.
Publisher: name: SADI journals
Year: 2024
Subjects: Authentication, Crime Reporting, MySQL, PHP, Real-Time Reporting, Validation Mechanisms, Web Application, Web Technologies.

description: In recent years, there has been a growing demand for innovative solutions to enhance public safety and bridge the gap between citizens and law enforcement agencies. "Eyes on the Street" addresses this need by introducing a real-time reporting app designed to empower citizens to report crimes they witness firsthand, thereby facilitating quicker response times and more efficient crime management. The web-based application provides a user-friendly interface that is accessible to anyone with internet connectivity. Using HTML, CSS, Bootstrap, JavaScript, PHP/Laravel, and MySQL database technologies, the system allows users to submit detailed accounts of the incidents they observed, including descriptions and relevant multimedia evidence. Key features include streamlined reporting processes, secure data transmission, and administrative oversight for verifying and responding to reports. Administrators, typically representing law enforcement or crime control agencies, have access to a dashboard where they can review incoming reports, verify their authenticity, and take appropriate actions. Eyes on the Street aims to create safer environments and enhance public trust in law enforcement efforts by harnessing the collective vigilance of citizens and fostering closer collaboration between communities and crime control agencies. This research contributes to the evolving landscape of civic technology by leveraging digital platforms to empower individuals and strengthen the fabric of public safety
title: ADCO, Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Cart. 32 (G 136), 745 folios, f. 0900
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire

description: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0900, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Neuvième cartulaire de Saint-Étienne de Dijon (1661 - 1684), Archives départementales de la Côte-d'Or, Cart. 32 (G 136), 745 folios, f. 0900, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye Saint-Étienne de Dijon
description: Provenance: http://www.wikidata.org/entity/Q15945019
Coordination polymers and discrete complexes of Ag(I)-N-(pyridylmethylene)anilines: Synthesis, crystal structures and photophysical properties
Creators: name: Njogu, Eric M.
name: Omondi, Bernard
name: Nyamori, Vincent O.
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Reactions of AgO2C2F3 with (E)-N-(pyridylmethylene)aniline in which the pyridyl N is in the p- or m-position yielded two 1-D coordination polymers, [(AgO2C2F3)2(La)2]n (La = (E)-2,6-diisopropyl-N-(pyrid-3-ylmethylene)aniline) (1) and [(AgOC2F3)2(Ld)2]n (Ld = (E)-2,6-diisopropyl-N-(pyrid-4-ylmethylene)aniline) (5), and three discrete complexes, [(AgO2C2F3)2(La)4] (2), [AgO2C2F3(Lb)2] (Lb = (E)-N-(pyrid-4-ylmethylene)aniline) (3) and [(AgOC2F3)2(Lc)4] (Lc = (E)-2,6-dimethyl-N-(pyrid-4-ylmethylene)aniline) (4). The structures were determined by MS, FT-IR and NMR spectroscopies, elemental analysis and single crystal XRD. 1 is an organometallic coordination polymer with silver in η1-arene coordination, but is a discrete dimeric complex 2 when crystallized from warm diethylether. The geometries around silver(I) in 1 and 4 are tetrahedral, ‘inverted seesaw’ in 2 and T-shaped in 3 and in all the anion seems to play a role. Ag(I) centers in 5 have distorted trigonal bipyramid and inverted seesaw geometries. The trifluoroacetate anions in these complexes display variable monodentate and short bridging coordination patterns. All complexes absorb and strongly emit UV-Vis radiation at room temperature.
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00006
Creators: name: de la Côte-d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2017
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: comptes
subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00006, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Hydrological Impacts of Land Use Change on Streamflow Quantity in A Sub-Catchment Of Klang Basin
Creators: name: HON LIM ONG
Publisher: name: Monash University
Year: 2017
Subjects: Environmental Science

description: The present study depicts the impact of land use changes on flooding potential of Sungai Dua Besar, Klang Valley, Malaysia. For this, the available land use maps from years 1966, 1984, 2002, and 2010 were used to predict the flooding potential in 2020. The study was piloted into three phases including land use change study, rainfall-runoff model development, and hydraulic model development to assess the flooding potential for estimated land use change. A land use prediction model was developed based on historical data and was compared with the future development plans. In the next stage, a rainfall-runoff (R-R) model was developed using Storm Water Management Model (SWMM). The calibrated model was then validated and evaluated using statistics. Finally, the potential flood prone areas were identified for different Average Recurrence Interval (ARI) for year 2020.
How community voices shape the future of gene drive research
Creators: name: Moronta Barrios, Felix
Publisher: name: ICGEB
Year: 2025
Subjects: subject: Gene Drive Technology

description: The potential deployment of gene drive organisms raises ethical, ecological, and governance challenges. This article explores the crucial role of community engagement in shaping gene drive research, moving beyond informational outreach to inclusive decision-making frameworks. Drawing on recent case studies and stakeholder insights, we examine the barriers to meaningful participation, the shortcomings of traditional consent models, and innovative strategies to integrate local knowledge into governance structures. By addressing power imbalances and communication gaps, this review highlights the pathways for ethical and effective community engagement. As a living literature review, this article will be updated as new relevant evidence emerges.
Probing the behavior of calf thymus DNA upon binding to a carboxamide fungicide boscalid: insights from spectroscopic and molecular docking approaches
Creators: name: Shi, Jie-Hua
name: Yan-Yue Lou
name: Zhou, Kai-Li
name: Pan, Dong-Qi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Cancer
subject: Computational Biology

description: Probing the behavior of calf thymus DNA upon binding to a carboxamide fungicide boscalid: insights from spectroscopic and molecular docking approaches
Ubiquitous Computing for knowledge transfer, exhibition design and museum operations
Creators: name: (:Unkn) Unknown
Publisher: name: Fachhochschule Nordwestschweiz FHNW
Year: 2020
Subjects: Ubiquitous computing
internet of things
museum studies
exhibition design
sensor-actor-network
HCI
UX
usability study
spatial storytelling
context awareness
location sensitivity

description: The project explores how exhibits and exhibition spaces can be augmented by interactive media to inform and emotionally involve visitors without the need of supplemental interface devices with additional information layers. From the perspectives of scenography, museology and engineering the potential of ubiComp for exhibition design, knowledge transfer and museum operations is considered and elaborated into a respective design toolkit.
Cytotoxic triterpenes from Salvia buchananii roots
Creators: name: Khadidja Aya Beladjila
name: Cotugno, Roberta
name: Djemaa Berrehal
name: Kabouche, Zahia
name: Tommasi, Nunziatina De
name: Braca, Alessandra
name: Leo, Marinella De
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: Hematology

description: A pentacyclic triterpene, named salvibuchanic acid (1), together with five known compounds, were isolated from the roots of Salvia buchananii Hedge (Lamiaceae). The structural characterisation of all compounds was performed by spectroscopic analyses, including 1D and 2D NMR and HRESIMS experiments. The lupane triterpene (1) and hyptadienic acid (2) were investigated for their potential cytotoxic activity on Jurkat, HeLa and MCF7 cell lines. Both compounds showed an interesting antiproliferative activity with similar potency in all cell lines. By means of flow cytometric studies, hyptadienic acid (2) induced in HeLa cells a S cell cycle block, while 1 elicited both cytostatic and cytotoxic responses.