cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Abgestempelt
Creators: name: Krenn, Tanja
Year: 2009

description: Zusammenfassung Diese Arbeit befasst sich mit der Problematik der Etikettierung und Stigmatisierung im Bereich der Kindergartenintegration. Ausgehend von einem geschichtlichen Rückblick auf die Entwicklung des pädagogischen Grundgedankens der Integration als gemeinsame Erziehung von Kindern mit und ohne Behinderung, wird erörtert, inwieweit die Pädagogik im Allgemeinen und die niederösterreichische Kindergartenpädagogik im Speziellen Phasen der Exklusion und Segregation durch Einsatz von Integration überwunden hat bzw. inwieweit einer Integrationspädagogik segregative Elemente zwangsläufig inhärent sind. Dabei wird besonders auf den Vorgang der Kategorisierung eingegangen, der einerseits notwendig für Integration ist, andererseits etikettierende und stigmatisierende Auswirkungen hat, die durch Integration und Inklusion überwunden werden sollen. Im Anschluss daran erfolgt die Darstellung des Konzepts des Labeling Approaches, das sich mit der Thematik der Abweichung und damit einhergehender Stigmatisierung beschäftigt, und es wird überprüft inwieweit dieses Konzept auf die Kindergartenintegration angewandt werden kann. Dem theoretischen Teil folgt eine empirische Untersuchung mittels problemzentrierter Interviews von professionell im Bereich Kindergartenintegration Tätiger und inhaltsanalytischer Aufarbeitung des Materials. Die Studie gründet auf den theoretischen Vorannahmen und beschäftigt sich mit zwei Fragen. Zum einen geht es darum festzustellen, nach welchen Kriterien die Kategorisierung in „Regelkindergartenkind“, „Integrationskind im Regelkindergarten“, „Integrationskind in der heilpädagogisch-integrativen Gruppe“ erfolgt bzw. welche Kriterien eine Exklusion rechtfertigen. Es zeigt sich, dass keine klaren Kriterien genannt werden können, sondern dass auf sehr allgemeine Formulierungen zurückgegriffen wird, die eine Abweichung in Entwicklung und Verhalten beschreiben. Zahlreiche „heimliche“ Kriterien determinieren die Entscheidung über einen sonderpädagogischen Förderbedarf, ohne dass den Befragten das Ausmaß des Einflusses bzw. ihre eigenen Vorurteile gegenüber bestimmten Personen(gruppen) bewusst sind. Zum anderen beschäftigt sich die Untersuchung mit der Frage, inwieweit bei den professionell im Bereich Kindergartenintegration Tätigen ein Problembewusstsein vorherrscht für eine mit der Zuschreibung des sonderpädagogischen Förderbedarfs eventuell einhergehende Etikettierung und Stigmatisierung. Das Problembewusstsein in Bezug auf Etikettierung und Stigmatisierung ist sehr gering, vor allem dort, wo es um die Auswirkungen der Zuschreibung auf die eigene Praxis, also die der Kindergartenintegration, geht.
Imaging challenges in patients with severe aortic stenosis and heart failure : did we find a way out of the labyrinth?
Creators: name: Gonska, Birgid
name: Buckert, Dominik
name: Mörike, Johannes
name: Scharnbeck, Dominik
name: Kersten, Johannes
name: Cuspidi, Cesare
name: Rottbauer, Wolfgang
name: Tadic, Marijana
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: aortic stenosis
subject: cardiac magnetic resonance
subject: computed tomography
subject: TAVR
subject: DDC 610 / Medicine & health
subject: Aortic valve stenosis
subject: Echocardiography
subject: Magnetic resonance imaging
subject: Aortenstenose
subject: Computertomografie

description: Aortic stenosis (AS) is the most frequent degenerative valvular disease in developed countries. Its incidence has been constantly rising due to population aging. The diagnosis of AS was considered straightforward for a very long time. High gradients and reduced aortic valve area were considered as “sine qua non” in diagnosis of AS until a growing body of evidence showed that patients with low gradients could also have severe AS with the same or even worse outcome. This completely changed the paradigm of AS diagnosis and involved large numbers of parameters that had never been used in the evaluation of AS severity. Low gradient AS patients may present with heart failure (HF) with preserved or reduced left ventricular ejection fraction (LVEF), associated with changes in cardiac output and flow across the aortic valve. These patients with low-flow low-gradient or paradoxical low-flow low-gradient AS are particularly challenging to diagnose, and cardiac output and flow across the aortic valve have become the most relevant parameters in evaluation of AS, besides gradients and aortic valve area. The introduction of other imaging modalities in the diagnosis of AS significantly improved our knowledge about cardiac mechanics, tissue characterization of myocardium, calcium and inflammation burden of the aortic valve, and their impact on severity, progression and prognosis of AS, not only in symptomatic but also in asymptomatic patients. However, a variety of novel parameters also brought uncertainty regarding the clinical relevance of these indices, as well as the necessity for their validation in everyday practice. The aim of this review is to summarize the prevalence of HF in patients with severe AS and elaborate on the diagnostic challenges and advantages of comprehensive multimodality cardiac imaging to identify the patients that may benefit from surgical or transcatheter aortic valve replacement, as well as parameters that may help during follow-up.
Additional file 2 of Attitudes, beliefs, and recommendations for persistent low back pain patients: cross-sectional surveys of students and faculty at a chiropractic college
Creators: name: Muller, Ryan D.
name: Cooper, Jesse
name: Gliedt, Jordan A.
name: Pohlman, Katherine A.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Neuroscience
subject: Biotechnology
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Science Policy
subject: Mental Health

description: Supplementary Material 2
title: Problemlagen und Problemprofile einer Entwicklungsprozesse unterstützenden Begleitung
Creators: name: Klenovsky, Michael
Year: 2009

description: Es kann davon ausgegangen werden, dass im Rahmen einer Entwicklungsprozesse unterstützenden Begleitung immer wieder vergleichbare Problemlagen auftauchen. Fasst man diese Problemlagen zu sogenannten Problemprofilen zusammen, können auf diese Art und Weise Erkenntnisse über Entwicklungsbegleitung gewonnen werden, die Verstehensprozesse im Kontext des zu untersuchenden Einzelfalls fördern werden, beziehungsweise lassen sich durch dieses Vorgehen die individuellen Bedingungen für die Entwicklung des beschriebenen Jugendlichen explorieren. In der Erschließung der Protokolle und ihrer Rückbindung an die Praxis des therapeutischen Gefährten, wurde eine deskriptive, analytische und problemheuristische Vorgehensweise verfolgt, das heißt, dass die drei ausgewählten Theoriegebiete (Übergangsobjekte, der Gegenwartsmoment, Containment und Mentalisierung) jeweils als Ausgangspunkte und Referenz zur Exploration herangezogen wurden. Daraus ließen sich schließlich drei Problemprofile generieren, die es erlaubten, den Einzelfall themengeleitet zu erschließen. Durch diese Vorgehensweise wurde einerseits versucht Theorie und Einzelfallpraxis miteinander zu verknüpfen. Andererseits konnte veranschaulicht werden, dass nach Ablauf der zwei jährigen therapeutischen Begleitung die Selbstkonzeption des Jugendlichen modifiziert wurde, die Identitätsbildung signifikant gefördert werden konnte und eine äußerst stabile Beziehung zwischen dem Jugendlichen und seinem therapeutischen Gefährten entstanden ist, was sich generell sehr positiv auf die Beziehungs- und Bindungserfahrungen des Jungen ausgewirkt hat. Darüber hinaus konnten im Rahmen der pädagogischen Entwicklungsbegleitung belastende Vergangenheitserlebnisse so umgestaltet werden, dass sie weniger leidvoll erlebt werden mussten. Es wurde möglich, die Reflexionsfähigkeit des Jugendlichen deutlich zu erhöhen und nicht zuletzt konnten auch in der Entwicklung weiterführende Mentalisierungsprozesse gefördert werden.
sj-docx-1-tam-10.1177_17588359221128356 – Supplemental material for Efficacy of neoadjuvant docetaxel + cisplatin chemo-hormonal therapy versus docetaxel chemo-hormonal therapy in patients with locally advanced prostate cancer with germline DNA damage repair gene alterations
Creators: name: Chi, Chenfei
name: Liu, Jiazhou
name: Fan, Liancheng
name: Zhu, Yinjie
name: Wang, Yanqing
name: Sha, Jianjun
name: Huang, Yiran
name: Dong, Baijun
name: Pan, Jiahua
name: Xue, Wei
Publisher: name: SAGE Journals
Year: 2022
Subjects: Oncology and Carcinogenesis not elsewhere classified
Aged Health Care
Pharmacology and Pharmaceutical Sciences not elsewhere classified
Respiratory Diseases

description: Supplemental material, sj-docx-1-tam-10.1177_17588359221128356 for Efficacy of neoadjuvant docetaxel + cisplatin chemo-hormonal therapy versus docetaxel chemo-hormonal therapy in patients with locally advanced prostate cancer with germline DNA damage repair gene alterations by Chenfei Chi, Jiazhou Liu, Liancheng Fan, Yinjie Zhu, Yanqing Wang, Jianjun Sha, Yiran Huang, Baijun Dong, Jiahua Pan and Wei Xue in Therapeutic Advances in Medical Oncology
Unruly Acts: Queer Masculinities in Akram Zaatari’s Lens-Based Artworks
Creators: name: Eliev, Elia
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2018
Subjects: Contemporary art
Queer
Lebanon
Masculinities

description: Over the past decade, scholarly works have examined the plurality and diversity of men in relation to social practices of Arab cultures, while also examining discourses of violence, militarization and hegemonic masculinity in times of war and conflict. However, there has been little discussion and critical literature concerning non- heterosexual (or queer) representations of masculinities in the Arab world. Within such context, this dissertation addresses the emerging and shifting visual representations of ‘queer’ masculinities as they are artistically performed in the contemporary lens-based artworks of internationally recognized Lebanese artist Akram Zaatari. Much of the research on queerness in the Arab region risks falling into a colonialist and liberatory framework that seeks to discover an ‘authentic’ queer identity. Contrary to such approaches, I argue for the fluidity of a local queer Arab model of disidentification underpinning Zaatari’s artworks, which questions our perceived realities of both queerness and hegemonic masculinity in Post-Civil War Lebanon. Taking an interdisciplinary approach that integrates cross-cultural comparative and queer visual analysis, I locate Zaatari’s artworks within a larger sociocultural context, as well as within and in tension with existing feminist and contemporary art discourses on the body, identity, and performativity. By examining visual and textual representations of local queer masculinities, this dissertation engages in dynamic discussions on the process of masculinization and elaborates on its future cultural and artistic trends both in the Arab world and in Western countries.
AJP Regu - Supplemental Tables.pdf
Creators: name: Thurston, Taylor
name: Amann, Markus
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420702
subject: Exercise physiology
classificationCode: 320899
subject: Medical physiology not elsewhere classified

description: Patients with hypertension (HTN) are characterized by exaggerated vascular resistance and mean arterial pressure (MAP), and a compromised leg blood flow (QL) response to exercise recruiting a small muscle mass. However, the impact of hypertension on peripheral hemodynamics and the development of neuromuscular fatigue during locomotor activities, which critically depends on QL, remain unknown. Eight HTN (143±11mmHg / 95±6mmHg; 45±13years) and 8 matched (age, activity) controls (120±6mmHg / 77±7mmHg; CTRL) performed constant-load cycling exercise at 25, 50, and 75W (for 4-min each), and at 165±41W (for 5-min). Exercise-induced locomotor muscle fatigue was quantified as the pre- to post-exercise change in quadriceps twitch-torque (∆Qtw, peripheral fatigue) and voluntary activation (∆VA%, central fatigue). QL (Doppler-ultrasound) and leg vascular conductance (LVC) were determined during cycling at 25, 50, and 75W. Heart Rate and ventilatory responses were recorded during all intensities. MAP during exercise was, on average, ~21mmHg higher (P=0.002) and LVC ~39% lower (P=0.001) in HTN compared to CTRL. QL was consistently between 20-30% lower (P=0.004) and heart rate was significantly higher in HTN. Exercise-induced peripheral (∆Qtw: -53±19% vs -25±23%) and central (∆VA%: -7±5% vs -3±2%) fatigue were significantly greater in HTN compared to CTRL. In addition to an exaggerated MAP, LVC and QL were lower during exercise in HTN compared to CTRL. Given the critical role of QL in determining the development of neuromuscular fatigue, these hemodynamic impairments likely accounted for the faster development of neuromuscular fatigue characterizing hypertensive individuals during locomotor exercise.
Additional file 2 of USF1 transcriptionally activates USP14 to drive atherosclerosis by promoting EndMT through NLRC5/Smad2/3 axis
Creators: name: Zhang, Zhiwen
name: Guo, Quan
name: Ma, Chao
name: Zhao, Zhenzhou
name: Shi, Qingbo
name: Yu, Haosen
name: Rao, Lixin
name: Li, Muwei
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Computational Biology

description: Supplementary Material 2
Information effects of managerial turnover on effort and performance : evidence from the German Bundesliga
Creators: name: Kleinknecht, Janina
name: Würtenberger, Daniel
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: DDC 330 / Economics
subject: Soccer; Germany
subject: Soccer managing
subject: Turnover (Business)
subject: Performance
subject: Fußballbundesliga
subject: Führungskraft; Nachfolge
subject: Leistungsbewertung

description: Managerial turnover induces an information loss regarding managers' knowledge about subordinates' abilities that might increase subordinates' incentives to exhibit effort to impress the new manager. To identify how this affects short‐term performance, we analyze within‐season coach turnovers in the German Bundesliga and consider low and high information loss by differentiating between insider and outsider successors. We use a generalized version of the synthetic control method to construct an accurate counterfactual scenario ensuring that results are not simply due to regression‐to‐the‐mean. We find performance improvements for insider and outsider successors, but only outsider successors induce players to exhibit higher effort.
Thurston - Hypertension_Supplemental Tables.pdf
Creators: name: Thurston, Taylor
name: Amann, Markus
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 420702
subject: Exercise physiology
classificationCode: 320899
subject: Medical physiology not elsewhere classified

description: Patients with hypertension (HTN) are characterized by exaggerated vascular resistance and mean arterial pressure (MAP), and a compromised leg blood flow (QL) response to exercise recruiting a small muscle mass. However, the impact of hypertension on peripheral hemodynamics and the development of neuromuscular fatigue during locomotor activities, which critically depends on QL, remain unknown. Eight HTN (143±11mmHg / 95±6mmHg; 45±13years) and 8 matched (age, activity) controls (120±6mmHg / 77±7mmHg; CTRL) performed constant-load cycling exercise at 25, 50, and 75W (for 4-min each), and at 165±41W (for 5-min). Exercise-induced locomotor muscle fatigue was quantified as the pre- to post-exercise change in quadriceps twitch-torque (∆Qtw, peripheral fatigue) and voluntary activation (∆VA%, central fatigue). QL (Doppler-ultrasound) and leg vascular conductance (LVC) were determined during cycling at 25, 50, and 75W. Heart Rate and ventilatory responses were recorded during all intensities. MAP during exercise was, on average, ~21mmHg higher (P=0.002) and LVC ~39% lower (P=0.001) in HTN compared to CTRL. QL was consistently between 20-30% lower (P=0.004) and heart rate was significantly higher in HTN. Exercise-induced peripheral (∆Qtw: -53±19% vs -25±23%) and central (∆VA%: -7±5% vs -3±2%) fatigue were significantly greater in HTN compared to CTRL. In addition to an exaggerated MAP, LVC and QL were lower during exercise in HTN compared to CTRL. Given the critical role of QL in determining the development of neuromuscular fatigue, these hemodynamic impairments likely accounted for the faster development of neuromuscular fatigue characterizing hypertensive individuals during locomotor exercise.
Berufswechsel nach Querschnittlähmungen: Der Einfluss eines Berufswechsels auf die Person-Job-Passung und die wahrgenommene Arbeitsqualität von Personen mit Querschnittlähmung
Creators: name: Beck, Selina
Publisher: name: Hochschule für Angewandte Psychologie FHNW
Year: 2024
Subjects: subject: Person Job Passung
subject: Arbeitsqualität
subject: nachhaltige Arbeitsintegration
subject: Berufswechsel
subject: Querschnittlähmung
subject: 150 - Psychologie

description: Oftmals geht der Eintritt einer Querschnittlähmung mit einer veränderten beruflichen Situation einher. Individualisierte Wiedereingliederungsmassnahmen von ParaWork helfen, die Betroffenen wieder in den Arbeitsprozess zu integrieren, wobei insbesondere die Person Job Passung und die wahrgenommene Arbeitsqualität zentral sind, um eine nachhaltige Arbeitsintegration zu ermöglichen. Auf der Grundlage psychologischer Theorien werden Personen, die nach Eintritt der Querschnittlähmung ihren Beruf wechseln mussten und Personen , die im gleichen Beruf verbleiben konnten, in ihrer Person Job Passung und wahrgenommenen Arbeitsqualität verglichen . Dabei wird die Passung von Person und Arbeitsplatz mit den Person Job Match Dimensionen Anforderungs-Fähigkeiten-Passung Bedürfnis Angebots Passung und Interessensübereinstimmung untersucht, während die wahrgenommene Arbeitsqualität anhand der Indikatoren Arbeitszufriedenheit, Arbeitsleistung und Arbeitsstress analysiert wird . Zur Untersuchung des Unterschieds zwischen den beiden Gruppen wurde ein quantitatives Querschnittdesign angewendet, wobei Daten einer mittels Fragebogen durchgeführten Begleitevaluationen der Unterstützungsangebote von ParaWork verwendet wurden. Die Erkenntnisse der durchgeführten Mann Whitney U Tests und Kontingenzanalysen zeigen, dass sich die beiden Gruppen in allen untersuchten Dimensionen nicht unterscheiden. Personen, die mit Hilfe der erhaltenen Wiedereingliederungsmassnahmen von ParaWork trotz Berufswechsel in den Arbeitsmarkt zurückfinden, erreichen eine ebenso gute Person Job Passung und wahrgenommene Arbeitsqualität wie Personen, die nach Eintritt der Querschnittlähmung im gleichen Beruf verbleiben können. Die explorative post-hoc Datenanalyse zeigt jedoch, dass nicht alle Personen, die ein e Querschnittlähmung erlitten haben und dadurch ihren Beruf wechseln müssen in die Arbeitswelt zurück finden.
Compressão Adaptativa de Imagens Médicas: Preservação Diagnóstica com Alta Eficiência
Creators: name: Litaiff, Filipe
Publisher: name: Zenodo
Year: 2025

description: A gestão de imagens médicas representa um desafio crescente para instituições de saúdedevido ao aumento exponencial no volume de exames radiológicos digitais. Este estudoapresenta uma metodologia de compressão adaptativa para imagens médicas que consideraas características específicas de cada modalidade, fabricante e tipo de exame, ajustandodinamicamente os parâmetros de compressão. Realizamos uma prova de conceito em umgrande centro diagnóstico brasileiro para avaliar a eficácia da compressão adaptativa empreservar a qualidade diagnóstica enquanto reduz significativamente o volume de dados.Radiologistas especialistas avaliaram exames originais e comprimidos de forma cega,considerando qualidade de imagem, similaridade e adequação diagnóstica. Os resultadosdemonstraram que a compressão adaptativa alcançou taxas de redução entre 75% e 97% nasdiferentes modalidades, mantendo a qualidade diagnóstica equivalente às imagens originaisem mais de 95% dos casos. Em algumas instâncias, as imagens comprimidas foram avaliadascom qualidade superior às originais. Este estudo valida a compressão adaptativa como umasolução viável para otimizar o armazenamento e a transmissão de dados médicos semcomprometer a precisão diagnóstica, oferecendo potencial significativo para redução de custosoperacionais em infraestrutura de TI para saúde.
sj-docx-1-jmq-10.1177_10776990221124942 – Supplemental material for No Escape From the Media Gates? How Public Support and Issue Salience Shape Interest Groups’ Media Prominence
Creators: name: Willems, Evelien
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications
subject: Education

description: Supplemental material, sj-docx-1-jmq-10.1177_10776990221124942 for No Escape From the Media Gates? How Public Support and Issue Salience Shape Interest Groups’ Media Prominence by Evelien Willems in Journalism & Mass Communication Quarterly
Mirror of volume functionals on manifolds with special holonomy
Creators: name: Kawai, Kotaro
name: Yamamoto, Hikaru
Publisher: name: arXiv
Year: 2021
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We can define the ``volume'' $V$ for Hermitian connections on a Hermitian complex line bundle over a Riemannian manifold $X$, which can be considered to be the ``mirror'' of the standard volume for submanifolds. This is called the Dirac-Born-Infeld (DBI) action in physics. In this paper, (1) we introduce the negative gradient flow of $V$, which we call the line bundle mean curvature flow. Then, we show the short-time existence and uniqueness of this flow. When $X$ is Kähler, we relate the negative gradient of $V$ to the angle function and deduce the mean curvature for Hermitian metrics on a holomorphic line bundle defined by Jacob and Yau. (2) We relate the functional $V$ to a deformed Hermitian Yang--Mills (dHYM) connection, a deformed Donaldson--Thomas connection for a $G_2$-manifold (a $G_2$-dDT connection), a deformed Donaldson--Thomas connection for a ${\rm Spin}(7)$-manifold (a ${\rm Spin}(7)$-dDT connection), which are considered to be the ``mirror'' of special Lagrangian, (co)associative and Cayley submanifolds, respectively. When $X$ is a compact ${\rm Spin}(7)$-manifold, we prove the ``mirror'' of the Cayley equality, which implies the following. (a) Any ${\rm Spin}(7)$-dDT connection is a global minimizer of $V$ and its value is topological. (b) Any ${\rm Spin}(7)$-dDT connection is flat on a flat line bundle. (c) If $X$ is a product of $S^1$ and a compact $G_2$-manifold $Y$, any ${\rm Spin}(7)$-dDT connection on the pullback of the Hermitian complex line bundle over $Y$ is the pullback of a $G_2$-dDT connection modulo closed 1-forms. We also prove analogous statements for $G_2$-manifolds and Kähler manifolds of dimension 3 or 4.
description: 62 pages, v2: minor corrections, final version
sj-docx-1-jiv-10.1177_08862605221127193 – Supplemental material for Dublin Anti-Bullying Self-Efficacy Models and Scales: Development and Validation
Creators: name: Sargioti, Aikaterini
name: Kuldas, Seffetullah
name: Foody, Mairéad
name: Viejo Otero, Paloma
name: Kinahan, Angela
name: Canning, Colm
name: Heaney, Darran
name: O’Higgins Norman, James
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: 160299 Criminology not elsewhere classified
subject: FOS: Law

description: Supplemental material, sj-docx-1-jiv-10.1177_08862605221127193 for Dublin Anti-Bullying Self-Efficacy Models and Scales: Development and Validation by Aikaterini Sargioti, Seffetullah Kuldas, Mairéad Foody, Paloma Viejo Otero, Angela Kinahan, Colm Canning, Darran Heaney and James O’Higgins Norman in Journal of Interpersonal Violence
Treatment satisfaction in 5q-spinal muscular atrophy under nusinersen therapy
Creators: name: Osmanovic, Alma
name: Ranxha, Gresa
name: Kumpe, Mareike
name: Wurster, Claudia D.
name: Stolte, Benjamin
name: Cordts, Isabell
name: Günther, René
name: Freigang, Maren
name: Müschen, Lars H.
name: Binz, Camilla
name: Hermann, Andreas
name: Deschauer, Marcus
name: Lingor, Paul
name: Ludolph, Albert C.
name: Hagenacker, Tim
name: Schreiber-Katz, Olivia
name: Petri, Susanne
Publisher: name: Universität Ulm
Year: 2021
Subjects: subject: antisense oligonucleotide
subject: nusinersen
subject: patient-reported outcome measures
subject: spinal muscular atrophy
subject: treatment satisfaction
subject: TSQM-1.4©
subject: DDC 610 / Medicine & health
subject: Patient Reported Outcome Measures
subject: Muscular Atrophy, Spinal
subject: Oligonucleotides, Antisense
subject: Antisense-Oligonucleotide
subject: Spinale Muskelatrophie

description: Background: Nusinersen was the first approved disease-modifying therapy for all 5q-spinal muscular atrophy (SMA) patients regardless of age or disease severity. Its efficacy in adults has recently been demonstrated in a large cohort by motor outcome measures, which were only partially suitable to detect changes in very mildly or severely affected patients. Patient-reported outcome measures (PROs) have been suggested as a valuable addition. Here, we aimed to assess treatment satisfaction and investigate whether it may be a useful PRO to monitor SMA patients. Methods: We enrolled 91 mainly adult 5q-SMA patients treated with nusinersen in a national, multicenter, cross-sectional observational study. 21 patients underwent longitudinal follow up. Patients’ satisfaction with treatment in four dimensions (global, effectiveness, convenience, side effects) was assessed by the Treatment Satisfaction Questionnaire for Medication German version 1.4 (TSQM-1.4©) and related to clinical parameters, motor scores, and treatment duration. Results: More than 90% of SMA patients were consistently satisfied over a median treatment duration of 10 months. Highest mean scores were observed in the dimensions ‘side effects,’ ‘global satisfaction,’ and ‘effectiveness’ (93.5 ± 14.8 versus 73.1 ± 21.0 and 64.8 ± 20.6, respectively). Patients’ satisfaction with the convenience of treatment was considerably lower (43.6 ± 20.2). Interestingly, satisfaction with the effectiveness was higher in ambulatory (p = 0.014) compared with non-ambulatory patients and directly correlated to motor outcome measures. Five non-ambulatory patients withdrew from therapy. All of them presented with a deterioration of motor outcome measures and reported dissatisfaction with treatment effectiveness and convenience. Conclusion: Most patients were satisfied with nusinersen treatment effectiveness. Less severely affected patients indicated higher satisfaction. The TSQM-1.4© helped to identify therapy non-responders, who mainly addressed dissatisfaction with effectiveness and convenience. We suggest introducing the TSQM-1.4© as an additional PRO in SMA into clinical practice.
Additional file 1 of Highly sensitive therapeutic drug monitoring of infliximab in serum by targeted mass spectrometry in comparison to ELISA data
Creators: name: Hentschel, Andreas
name: Piontek, Gina
name: Dahlmann, Rob
name: Findeisen, Peter
name: Sakson, Roman
name: Carbow, Phil
name: Renné, Thomas
name: Reinders, Yvonne
name: Sickmann, Albert
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified

description: Supplementary Material 1: Calibration curves of the ASQ peptide of infliximab. Curves were generated and measured by two different researchers with a time difference of 6 month. Both calibration curves show robust results in regard to their LOD and LLOQ. Each calibration point was measured 3 time with independent replicates. The LOD is marked with the purple line, the LLOQ is marked with the blue line
Exploring the role of immersive technology in digitally representing contemporary crafts within hybrid museum exhibitions: a scoping review
Creators: name: Zhang, Rui
name: Peng, Fanke
name: Gwilt, Ian
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Biological Sciences not elsewhere classified
Science Policy

description: This study focuses on the complex design process of developing museum exhibitions that feature contemporary craft artifacts, while leveraging immersive technologies such as virtual reality (VR), augmented reality (AR), and extended reality (XR) to augment the visitor experience of these objects. Through a scoping review of current practices, it investigates how these technologies augment the display and interpretation of diverse craft materials within museum contexts. Through an analysis of 35 peer-reviewed publications related to the application of immersive technologies in museums, it delineates the roles these technologies play in the design and presentation of hybrid (physical/virtual) museum exhibitions, contrasting their effectiveness and challenges with traditional physical displays. By emphasizing the design process, this study sheds light on innovative strategies for enhancing visitor engagement and digitally preserving contemporary craft knowledge, offering a detailed roadmap for future researchers, practitioners, and cultural institutions interested in the intersection of technology, crafts, and cultural representation.
Connecting boundary layer dynamics with extreme bulk dissipation events in Rayleigh-Bénard flow
Creators: name: Valori, Valentina
name: Schumacher, Joerg
Publisher: name: arXiv
Year: 2021
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We study the connection between extreme events of thermal and kinetic energy dissipation rates in the bulk of three-dimensional Rayleigh-Bénard convection and the wall shear stress patterns at the top and the bottom planes that enclose the layer. Zero points of this two-dimensional vector field stand for detachments of strong thermal plumes. If their position at the opposite planes and a given time is close then they can be considered as precursors for high-amplitude bulk dissipation events triggered by plume collisions or close passings. This scenario requires a breaking of the synchronicity of the boundary layer dynamics at both plates which is found to be in line with a transition of the bulk derivative statistics from Gaussian to intermittent. Our studies are based on three-dimensional high-resolution direct numerical simulations for moderate Rayleigh numbers between $Ra=10^4$ and $5\times 10^5$.
Universität Ulm 2014
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 050 / General serial publications
subject: Research; Ulm
subject: Universities; Germany; Ulm
subject: Forschungsbericht
subject: Universität Ulm

description: Jahresbericht der Universität Ulm 2014 in deutscher und englischer Sprache
Effects of biphenyl polymerization on lithium deposition in commercial graphite/NMC lithium-ion pouch-cells during calendar aging at high temperature
Creators: name: Matadi, Bramy Pilipili
name: Geniès, Sylvie
name: Delaille, Arnaud
name: Waldmann, Thomas
name: Kasper, Michael
name: Wohlfahrt-Mehrens, Margret
name: Aguesse, Frederic
name: Bekaert, Emilie
name: Jiménez-Gordon, Isabel
name: Daniel, Lise
name: Fleury, Xavier
name: Bardet, Michel
name: Martin, Jean-Frédéric
name: Bultel, Yann
Publisher: name: Universität Ulm
Year: 2017
Subjects: subject: aging mechanisms
subject: calendar aging
subject: large scale pouch cells
subject: localized lithium deposition
subject: Post-Mortem analysis
subject: DDC 540 / Chemistry & allied sciences
subject: Lithium ion batteries
subject: Biphenyl

description: Metallic lithium deposition is a typical aging mechanism observed in lithium-ion cells at low temperature and/or at high charge rate. Lithium dendrite growth not only leads to strong capacity fading, it also causes safety concerns such as short-circuits in the cell. In applications such as electric vehicles, the use of lithium-ion batteries combines discharging, long rest time and charging phases. It is foremost a matter of lifetime and safety from the perspective of the consumer or the investor.This study presents the post-mortem analyses of commercial 16 Ah Graphite/NMC (Nickel Manganese Cobalt layered oxide) Li-ion pouch cells. The cells were degraded by calendar aging at high temperature with or without periodic capacity tests. Unexpected local depositions of metallic lithium were confirmed on graphite electrodes by Nuclear Magnetic Resonance (NMR). Biphenyl, a monomer additive present in the liquid electrolyte, generates gas during its polymerization reaction occurring at high temperature and at high state of charge. As a result, dry-out areas are present between the electrodes leading to high impedance regions and no charge transfer between the electrodes. It is at the border of these areas that lithium metal is deposited.
title: Medizinjournalismus - Inhalte, Akteure und Rahmenbedingungen
Creators: name: Nitsch, Martina
Year: 2008

description: Die Arbeit widmet sich im Rahmen einer Auftragsforschung für das Ludwig Boltzmann Institut für Health Technology Assessment den ökonomischen und rechtlichen Aspekten der österreichischen Medizin-und Gesundheitsberichterstattung. Es wurde davon ausgegangen, dass in der Medizin- und Gesundheitsberichterstattung neben Journalisten und Redakteuren, einerseits die pharmazeutische Industrie und anderseits Mediziner und Ärzte besonders große Einflussgrößen darstellen. Eine Analyse der Inhalte der Pharmaberichterstattung und das Aufzeigen der Relationen zwischen den einzelnen Akteuren und der jeweiligen Rahmenbedingungen bildete die Basis der Untersuchung. Ausgehend von der Überlegung, dass sich der Medizinjournalismus im Vergleich zum Journalismus anderer Ressorts in Bezug auf inhaltliche und ökonomische Faktoren wesentlich unterscheidet, wurde als theoretisches Kernstück die Nachrichtenwert-Theorie herangezogen. Den Ausgangspunkt bildete die Frage nach der Verallgemeinerbarkeit Theorie von Joachim Friedrich Staab. Bislang wurde deren Geltungsbereich nur im Bereich der politischen Berichterstattung nachgewiesen. Durch die Analyse der ökonomischen Hintergründe der einzelnen Akteure konnten Verbindungen zu weiteren kommunikationstheoretischen Ansätzen hergestellt werden. Zum einen wurde die Bedeutung von Agenda-Setting-Prozessen im Medizinjournalismus diskutiert. Dabei wurde ein erhöhtes Augenmerk auf die Pressearbeit der pharmazeutischen Industrie gelegt, die mit gezielten Agenda-Building-Prozessen in Verbindung gebracht wurde. Andererseits wurde auch die Funktion der Journalisten und Redakteure innerhalb des Agenda-Settings analysiert. Etwaige ökonomische und wirtschaftliche Interessen der letzt genannten Gruppe wurden zudem vor dem Hintergrund von PR-theoretischen Ansätzen thematisiert. Im Hinblick auf die Rolle bzw. die Funktion der Ärzte diente die Verbindung zur Opinion Leader-Forschung als aufschlussreich. Neben bestimmten persönlichen Eigenschaften wurde auch die Rolle von Ärzten innerhalb ihres sozialen Umfeldes diskutiert. Als ergänzendes qualitatives Element wurden neun Experteninterviews mit jeweils drei Vertretern der Redakteure/Journalisten, der Mediziner und der Pharmaindustrie durchgeführt. Die Ergebnisse der Inhaltsanalyse und der Interviews lassen darauf schließen, dass die Medizinberichterstattung auch von anderen Kriterien beeinflusst wird und somit nicht ausschließlich im Rahmen der Nachrichtenwert-Theorie erklärt werden kann. Die von Staab diskutierte Allgemeingültigkeit der Nachrichtenwert-Theorie und die Adäquatheit der Methode muss daher im Hinblick auf die Medizinberichterstattung angezweifelt werden. Dahingehend wird von der Autorin eine Einordnung der Theorie in ein übergeordnetes Modell, das auch externe Einflüsse berücksichtigt, vorgeschlagen.
sj-pdf-1-ajs-10.1177_03635465221124258 – Supplemental material for Early ACLR and Risk and Timing of Secondary Meniscal Injury Compared With Delayed ACLR or Nonoperative Treatment: A Time-to-Event Analysis Using Machine Learning
Creators: name: Lu, Yining
name: Jurgensmeier, Kevin
name: Till, Sara E.
name: Reinholz, Anna
name: Saris, Daniel B.F.
name: Camp, Christopher L.
name: Krych, Aaron J.
Publisher: name: SAGE Journals
Year: 2022
Subjects: Orthopaedics
Sports Medicine
Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465221124258 for Early ACLR and Risk and Timing of Secondary Meniscal Injury Compared With Delayed ACLR or Nonoperative Treatment: A Time-to-Event Analysis Using Machine Learning by Yining Lu, Kevin Jurgensmeier, Sara E. Till, Anna Reinholz, Daniel B.F. Saris, Christopher L. Camp and Aaron J. Krych in The American Journal of Sports Medicine
Wildlife-vehicle collisions at 42 Florida State Parks, 2005-2015
Creators: name: Jenkins, David
Publisher: name: Zenodo
Year: 2022

description: Peninsular Florida, USA: 9,254 WVC survey records collected by Florida State Parks personnel at 42 parks during a decade (2005-2015). Data represent observations of wildlife-vehicle collisions for birds (138 species), mammals (35 species), and reptiles (64 species). The 42 state parks encompassed a variety of Florida's ecosystems on the peninsula and keys (and North, but not the Florida panhandle) from barrier islands and the Everglades to pine flatwoods, sandhills, and urban areas. Climate ranged from subtropical in South Florida to warm temperate in North Florida.
description: Each row represents one observation event - see metadata tab in xls for explanations of columns. Note NAs in some parks for attendance. Please see the file named "data summary.txt" for an overview using the summary(data) command in R.
description: Florida State Park personnel collected WVC data as part of a statewide program, where data forms included date, general location (not GPS coordinates), species, and number of individuals for organisms killed on roads. Parks varied in how data were collected (staff or volunteers, temporal frequency and extent, roads) but all surveys were conducted while driving (i.e., none were conducted by walking road margins). Taxonomic identifications are to species level for birds, mammals, and reptiles. Data were iteratively cleaned to assure consistency (e.g., taxonomy, road names, etc.).
Diplomatique et histoire religieuse : les "actes clunisiens" permettent ils d'accéder à l'"être clunisien"?
Creators: name: Barret, Sébastien
Publisher: name: Zenodo
Year: 2024
Subjects: Cluny
diplomatics

description: Cluniac charters form a very specific and famous collection of historical documents, which has been the basis for numerous studies, including seminal works by André Déléage, Georges Duby, Didier Méhu, Isabelle Rosé or Barbara Rosenwein. Their sheer number, as well as the importance of the monastery that kept them in its archives made them an almost inexhaustible source of information and a most precious tool for researching social and economic ties, events, and emotions, to name but a few topics. At the same time, historians have asked through various angles what “being a Cluniac” meant, among them Dominique Iogna-Prat, Joachim Wollasch, Gert Melville or Glauco Maria Cantarella. All of these scholars made use of sources of various kinds, diplomatic sources among them. Charters and deeds are not the most evident resource for this kind of interrogation but should not be dismissed as irrelevant prima facie. Within the frame of the workshop, the present contribution would like to focus on Cluniac charters and whether they can contribute to explore questions of religious identities and, if yes, how; one additional difficulty being that trying to define such identities in historical perspective can be in itself a perilous undertaking.
The MARS COORDINATS WATER
Creators: name: Touloumidis, Stylianos
Publisher: name: Zenodo
Year: 2025
Subjects: subject: Mars
subject: Astrophysics
subject: Chemical sciences
subject: FOS: Chemical sciences
subject: Mercury, Planet
subject: Earth, Planet
subject: Planets
subject: Water engineering

description: Modern physics describes reality using discrete particles and fundamental 

forces. General relativity formulates gravity as a geometric curvature of 

spacetime, while quantum mechanics describes subatomic interactions through 

probabilistic wave functions. While these theories offer remarkable predictive 

power, they remain mathematically separate and conceptually incomplete.  

 

An alternative approach emerges from the understanding that **all physical 

quantities can be expressed as resonance phenomena**. This suggests that 

the universe does not consist of discrete objects but rather of continuous 

fields, whose properties are determined by resonance structures and harmonic 

frequencies.  

 

The foundation of this new perspective is given by the fundamental resonance 

equation:

 

                     Ξ = λ_CMB * f_CMB * T_K * c

 

where:

- **Ξ** = Universal resonance constant, the primary descriptor of all physical 

  interactions.  

- **λ_CMB** = Wavelength of the cosmic microwave background radiation (CMB).  

- **f_CMB** = Frequency of the CMB.  

- **T_K** = Temperature in Kelvin, defining the thermodynamic order of the universe.  

- **c** = Speed of light, interpreted here as a derived property rather than a 

  fundamental constant.  

 

This equation is **not an assumption but a mathematical necessity** arising 

from the interplay of wave mechanics and field interactions. It allows for 

the derivation of fundamental physics purely through resonance principles.
sj-pdf-1-jcb-10.1177_0271678X211056393 - Supplemental material for Lower cerebral oxygen utilization is associated with Alzheimer’s disease-related neurodegeneration and poorer cognitive performance among apolipoprotein E ε4 carriers
Creators: name: Robb, W Hudson
name: Khan, Omair A
name: Ahmed, Humza A
name: Li, Judy
name: Moore, Elizabeth E
name: Cambronero, Francis E
name: Pechman, Kimberly R
name: Liu, Dandan
name: Gifford, Katherine A
name: Landman, Bennett A
name: Donahue, Manus J
name: Hohman, Timothy J
name: Jefferson, Angela L
Publisher: name: SAGE Journals
Year: 2022
Subjects: subject: Emergency Medicine
subject: Endocrinology
subject: Medicine
subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Radiology and Organ Imaging
subject: Cell Biology
subject: Biochemistry
subject: Biological Sciences not elsewhere classified
subject: Neuroscience

description: Supplemental material, sj-pdf-1-jcb-10.1177_0271678X211056393 for Lower cerebral oxygen utilization is associated with Alzheimer’s disease-related neurodegeneration and poorer cognitive performance among apolipoprotein E ε4 carriers by W Hudson Robb, Omair A Khan, Humza A Ahmed, Judy Li, Elizabeth E Moore, Francis E Cambronero, Kimberly R Pechman, Dandan Liu, Katherine A Gifford, Bennett A Landman, Manus J Donahue, Timothy J Hohman and Angela L Jefferson in Journal of Cerebral Blood Flow & Metabolism
Perihematomal diffusion restriction in intracerebral hemorrhage depends on hematoma volume, but does not predict outcome
Creators: name: Stösser, Sebastian
name: Neugebauer, Hermann
name: Althaus, Katharina
name: Ludolph, Albert C.
name: Kassubek, Jan
name: Schocke, Michael
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: Intracerebral hemorrhage
subject: Cerebral edema
subject: DDC 610 / Medicine & health
subject: Cerebral hemorrhage
subject: Brain edema
subject: Blood pressure
subject: Diffusion magnetic resonance imaging
subject: Hirnblutung
subject: Hirnödem
subject: Diffusionsgewichtete Magnetresonanztomografie

description: Background: Perihematomal diffusion restriction (PDR) is a frequent finding in primary intracerebral hemorrhage (ICH) on diffusion-weighted MRI. Its frequency, associated clinical and imaging findings and impact on clinical outcome are not well understood. Methods: This is a retrospective single-center analysis of 172 patients with primary ICH who received MRI within 24 h from symptom onset. PDR was defined as a reduction of apparent diffusion coefficient below 550 × 10-6 mm2/s. Multivariate regression analyses were used to assess independent imaging and clinical predictors of PDR. Clinical outcome was assessed using the modified Rankin scale (mRS) at discharge. Results: PDR was present in 88 patients (51.2%). Median PDR volume was 1.1 ml (interquartile range 0.2-4.2). Multivariate analyses identified hematoma volume as the key independent predictor of PDR. The volume of perihematomal edema, lobar hematoma location and low diastolic blood pressure at admission were further predictors. Although the occurrence of PDR correlated with in-hospital mortality (75.0 vs. 43.4%, p < 0.001) and moderately severe to severe disability or death at discharge (mRS ≥4; 56.4 vs. 27.8%, p = 0.002), PDR was not an independent predictor of clinical outcome. In contrast, hematoma volume, ventricular extension of hemorrhage and higher age independently predicted an adverse clinical outcome. Conclusions: PDR is common after primary ICH within 24 h of symptom onset. Hematoma volume was identified as the key predictor of PDR. Although PDR was associated with mortality and severe disability, this effect was confounded by established risk factors. These results do not support a role of early PDR as prognostic factor after ICH independent of hematoma volume. © In Copyright http://rightsstatements.org/vocab/InC/1.0/
Additional file 1 of Proteomic analysis of breast cancer based on immune subtypes
Creators: name: Jeon, Yeonjin
name: Lee, GunHee
name: Jeong, Hwangkyo
name: Gong, Gyungyub
name: Kim, JiSun
name: Kim, Kyunggon
name: Jeong, Jae Ho
name: Lee, Hee Jin
Publisher: name: figshare
Year: 2024
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Figure S1. Survival rate between immune subtypes in the total cohort and TNBC cohort. (a) OS in three immune subtypes (p = 0.666) in the total cohort. (b) OS in two immune groups in the total cohort (p = 0.440). (c) RFS in three immune subtypes in the total cohort (p = 0.795). (d) RFS in two immune groups in the total cohort (p = 0.776). (e) OS in three immune subtypes (p = 0.777) in the TNBC cohort. (f) OS in two immune groups in the TNBC cohort (p = 0.930). (g) RFS in three immune subtypes in the TNBC cohort (p = 0.630). (h) RFS in two immune groups in the TNBC cohort (p = 0.820).