cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Additional file 1: Figure S1. of
                     Plasmodium falciparum uses vitamin E to avoid oxidative stress
Creators: name: Sussmann, Rodrigo
name: Fotoran, Wesley
name: Kimura, Emilia
name: Katzin, Alejandro
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Imaging evaluation of CellRox. Figure S2. Time course of ROS generation. Figure S3. RP-HPLC purification of Îą-tocopherol and its oxidation product. Figure S4. GC/MS identification of tocopherolquinone. Figure S5. Determination in vitro of inhibitory concentration of 50% of the growth of cercosporin in P. falciparum. (DOCX 847Â kb)
Amyttopsis Beier 1965
Creators: name: Naskrecki, Piotr
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Amyttopsis

description: Amyttopsis Beier 1965
Type species: Amyttopsis vinculata Beier 1965: 227.
Members of this genus are known only from West and Central Africa. They are diagnosed by the combination of the unique development of the 10th abdominal tergite of the male, the latero-ventral lobes of which form a pair of distinct, often twisted projections, and the shape of the cercus, which is always unarmed and strongly dorso-ventrally flattened. The character not mentioned by Beier (1965) in the generic diagnosis, but most likely present in all species of the genus is the presence of a partially sclerotized epiphallus. Unfortunately, although I had the opportunity to examine types of all described species of Amyttopsis, I did not dissect their gentalic structures, and thus cannot describe them here. The presence of a sclerotized epiphallus may indicate a close relationship of this genus to Anepitacta Br. -Watt. and Proamytta Beier, which are the only other genera of West African Meconematinae known to possess such structures.
description: Published as part of Naskrecki, Piotr, 2008, New species of arboreal predatory katydids from West Africa (Orthoptera: Tettigoniidae: Meconematinae), pp. 1-28 in Zootaxa 1732 on page 5, DOI: 10.5281/zenodo.181351
Trichomyia sinuosa Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia sinuosa

description: Trichomyia sinuosa Araújo & Bravo sp. nov.
(Figs. 41A–F)
Diagnosis. Basal expansion with a group of bristles on gonocoxite; sinuous arm of gonocoxite, C-shaped; two pairs of sclerotized projections in the aedeagal complex; one pair trifurcate, claw-shaped and one pair 1.3 times the length of aedeagus; ejaculatory apodeme short, 0.7 times the length of aedeagus.
Description. Male. Head subcircular in frontal view. Antenna with 13 flagellomeres; scape subcylindrical; pedicel subspherical; flagellomeres pyriform; ascoids 1.4 times as long as the length of flagellomere (Fig. 41A); 13th flagellomere subcylindrical with terminal apiculus separated by a suture (Fig. 41D). Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.6:0.7 (Fig. 41B). Wing: apex of Sc unsclerotized; R4+5 with base unsclerotized; r-m unsclerotized and m-cu absent (Fig. 41C). Male terminalia: Hypandrium and gonocoxites fused with a basal expansion with a group of bristles. Arm of gonocoxite very long tapering, C-shaped with a row of setulae. Gonostylus not visualized. Aedeagal complex with two pairs of sclerotized projections; one pair trifurcate, claw-shaped, and one pair 1.3 times the length of the aedeagus. Aedeagus with rounded tip, subtriangular (Fig. 41F). Ejaculatory apodeme short, 0.7 times the length of aedeagus. Epandrium with posterior margin larger than the anterior margin. Cercus angular with lateroapical bristles. Hypoproct with apical micropilosity. Epiproct subtriangular with rounded tip (Fig. 41E).
Female. Unknown.
Material examined. Brazil, Amazonas, Manacapuru, Cajatuba Km 69/3, 09.X.1998, holotype ♂, without
name of colector. (MZFS); 3 paratypes: 2 ♂, same locality, date as holotype. (MZFS); 1 ♂, Pará, Novo
Reparttimento, Vic. Bandeirante, Ramal dos sem terra, 22.VIII.1998, without name of colector (MZFS). Etymology. The epithet sinuosa is allusive to the shape of arm of gonocoxite. Distribution. Brazil—Amazonas, Pará.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 67-68, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Regulation of meiotic central spindle function, homolog bi-orientation and co-orientation in Drosophila oocytes
Creators: name: Das, Arunika
Publisher: name: No Publisher Supplied
Year: 2016

description: In the oocytes of many animals including humans, spindles are assembled in the absence of centrosomes. It is poorly understood what organizes the bipolar spindle in this system and directs attachment of chromosomes to opposing poles, a process known as bi-orientation. Previously it was shown that the kinesin 6 motor protein, Subito, is important for meiotic central spindle assembly and localization of the chromosomal passenger complex (CPC).  I analyzed the role of different domains of Subito, to understand what restricts the activity of the motor to the chromatin, in meiosis. I found that the N-terminus of Subito, is required for localization of the kinesin to microtubules possibly in conjunction with the C-terminus. I also identified domains of Subito N-terminus that are required for mitosis, but may be dispensable for meiosis.  I also analyzed mutants obtained from a synthetic lethal screen with Subito and found that the centralspindlin complex, is required for both homolog bi-orientation and Subito localization in meiosis. Surprisingly, I also found that downstream targets of this complex like Rho1 and Sticky (Citron kinase), are important for bi-orientation. In addition, another target from the screen, Polo kinase, which is a kinetochore protein is required for maintaining karyosome structure. Altogether, these results have given rise to a model where late cytokinesis proteins are involved in regulating central spindle assembly and directing bi-orientation possibly by modulating error correction by the kinase, Aurora B.  It is unclear how the CPC function is regulated to establish tension between homologs and correct errors. Phosphatases have been shown to be important for a similar function in mitosis. However the role of phosphatases in meiosis was unknown. I have found that Drosophila PP1 is required for maintaining karyosome structure, peri-centromeric cohesion and co-orientation at metaphase I, in an Aurora B dependent manner. Kinetochore assembly by Aurora B, is also opposed by PP1. These results taken together provide insight on how Aurora B activity is balanced in meiosis, and emphasize the important role played by PP1 in oocytes.
Effect of solvent on melting gel behavior
Creators: name: Degnah, Ahmed Abdulaziz M
Publisher: name: No Publisher Supplied
Year: 2016

description: Melting gel and hybrid glass are organic-inorganic materials derived from sol gel processing. The behavior of the melting gel is that it is a solid at room temperature, but when the melting gel is reheated to 110°C (T1) it becomes fluid. The melting gel has reversible behavior due to incomplete crosslinking between polysiloxane chains. When the melting gel is heated to its consolidation temperature of 150°C (T2) the gel no longer softens (T2>T1), because crosslinking is completed. The melting gel at the consolidation temperature becomes hybrid glass.   Melting gel coatings were applied to titanium alloy substrates. Melting gels were prepared containing phenyl substitutions with 1.0 mole Phenyltrimethoxysilane (PhTMS) in ratio to 0.25 moles of Diphenyldimethoxysilane (DPhDMS). The methanol to DPhDMS ratio was varied to change the thickness of the coatings.  The coatings were inspected visually to see that there is good adhesion between the coating and the substrate.  Nanoindenter tests were performed to determine hardness. The coated samples were placed in an oven and heated to 150ºC for 24, 48 or 96 hours before cooling back to room temperature, which took about 4 hours. The measurements of the hardness on samples containing 3 levels of solvent and heat treatment were collected by indentation technique. The best combination of solvent and temperature was 1:8 PhTMS:MeOH  for all temperatures.
Trichomyia spinicauda Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia spinicauda

description: Trichomyia spinicauda Araújo & Bravo sp. nov.
(Figs. 42A–F)
Diagnosis. R4+5 complete at base; r-m present; hypandrium fused with gonocoxites and with a medial posterior expansion, rounded apically; arm of gonocoxites directed upward with rod-like bristles on inner apex; ejaculatory apodeme 1.6 times the length of gonostylus.
Description. Male. Head subcircular in frontal view. Antenna incomplete in the studied specimens; scape about the same length as the subspherical pedicel; basal flagellomeres pyriform and eccentric; paired ascoids on each flagellomere, C-shaped, 1.3 times the length of flagellomere (Fig. 42A). Palpus with three segments; 1st segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.6:0.6 (Fig. 42B). Wing. R4+5 complete at base; r-m present; m-cu absent (Fig. 42D). Male terminalia: Hypandrium fused with gonocoxites, with a medial posterior apically rounded expansion (Fig. 42E). Arm of gonocoxites directed upward with rod-like bristles in the inner apex and a group of small and thick bristles on the base of arm (Figs. 42E, 42C). Gonostylus articulated to gonocoxite at the middle, bare, with apex directed upward. Aedeagal complex with two pairs of projections, the dorsal thinner than the subtriangular ventral projection. Aedeagus bifid ending before the apex of ventral projections in the aedeagal complex (Fig. 42E). Ejaculatory apodeme 1.6 times the length of gonostylus. Epandrium pilose, subrectangular (Fig. 42F). Cercus pilose with truncated apex in lateral view and a row of few, short and thick bristles (Figs. 42E, 42F). Hypoproct with apical micropilosity (Fig. 42F).
Female. Unknown.
Material examined. Brazil, Bahia, Coração de Maria municipality, holotype ♂, 14.VIII.2002, F. Bravo leg. (MZFS); 3 paratypes: 1 ♂, same locality and collector than holotype 18.XII.2003 (MZFS); 1 ♂ same locality of holotype, 18.XII.2003, I. Castro leg. (MZFS); 1 ♂ same locality of holotype, 02.XI.2003, I. Castro leg. (MZFS).
Etymology. From Latim, cauda, meaning tail; extreme part, and spina, spine; thorn referring to the arrangement of bristles at apex of arm of gonocoxite.
Distribution. Brazil—Bahia.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 68-69, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Design and characterization of salicylic acid-based hydrogels for protein delivery applications
Creators: name: Demirdirek, Bahar
Publisher: name: No Publisher Supplied
Year: 2016

description: Combination drug delivery has received much attention in the pharmaceutical industry to meet the need for increased efficacy and improved patient compliance. Hydrogels are cross-linked networks of hydrophilic polymers that resembles natural tissue and thus successfully developed for drug delivery applications. In three separate chapters, this dissertation describes novel salicylic acid-based hydrogel systems that concurrently deliver salicylic acid as well as the encapsulated protein. The hydrogels systems described herein are formed via physically and chemically cross-linking techniques.   First, salicylic acid-based poly(anhydride-esters) were physically cross-linked with poly(N-isopropylacrylamide-co-acrylic acid) via a solvent-casting technique to form injectable hydrogel systems. The physical interactions between these polymer systems were characterized by Fourier transform infrared spectroscopy. Bovine serum albumin, a representative protein, was successfully incorporated into the hydrogel systems. The release profiles of both salicylic acid and bovine serum albumin were ascertained.   Second, salicylic acid-based poly(anhydride-esters) were physically cross-linked with poly(acrylic acid) to develop pH-sensitive hydrogels for oral protein delivery. These systems were characterized using spectroscopic techniques such as Fourier transform infrared spectroscopy. Insulin was incorporated into these systems, release of both insulin and salicylic acid was determined to be pH-dependent. The physical and chemical stability of insulin was characterized following release from the hydrogel system. In addition, these systems displayed mucoadhesive behavior which may further enable insulin bioavailability. The results suggest that these systems may be useful for oral administration of insulin and salicylic acid.   Third, salicylic acid was chemically incorporated into hydrogel systems via attachment of salicylic acid to an itaconate moiety followed by cross-linking using acrylic acid and poly(ethylene glycol)-diacrylate via UV. The structure, swelling behavior, pore structure, salicylic acid release, rheological, and mucoadhesion behavior of these hydrogels were studied. These hydrogels systems showed pH-responsive behavior:  collapsing at acidic pH levels and leading to slower salicylic acid release, and swelling at higher pH conditions leading to salicylic acid release within 24 hours. Pore structure analysis showed a promising pore size for physically encapsulating of proteins.   In conclusion, these results suggested that these systems can potentially be used in combination delivery of proteins and salicylic acid.
Ceroctis interna
Creators: name: Bologna, Marco A.
name: Amore, Valentina
name: Pitzalis, Monica
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Meloidae
Ceroctis
Ceroctis interna

description: Ceroctis interna species group
Only the following Namibian species belongs to this group, mainly distributed in central Africa, phenetically well distinct by the elytral pattern characterized by the unicolour red apex of elytra and transverse fasciae. The group includes at least: C. angolana Borchmann, 1940 (which could be a symomym of C. blanda); C. blanda (Péringuey, 1892); C. congoana (Duvivier, 1890); C. interna (Harold, 1879).
Ceroctis blanda (Péringuey, 1892) (Fig. 3G)
Mylabris blanda Péringuey, 1892
Distribution. Angola, Botswana, northern Namibia, northwestern South Africa, and Zaire. Material esamine and literature records. [Kavango] Ndiyona: Niangana, 18.0000°S 20.6833°E (SMWN). [Otjozondjupa] Okahandja: Okahandja, 21.9833°S 16.9167°E (SMWN).
Other records: Ovampoland (Péringuey 1909, type locality; Pardo 1 958b); Namibia (Bologna 2000a). Remarks. The holotype of this species was examined at SAMC.
description: Published as part of Bologna, Marco A., Amore, Valentina & Pitzalis, Monica, 2018, Meloidae of Namibia (Coleoptera): taxonomy and faunistics with biogeographic and ecological notes, pp. 1-141 in Zootaxa 4373 (1) on page 52, DOI: 10.11646/zootaxa.4373.1.1, http://zenodo.org/record/1151722
Antibiotic resistance among the AIDS-immunocompromised
Creators: name: DeNegre, Ashley A.
Publisher: name: No Publisher Supplied
Year: 2016

description: First recognized in 1981, the AIDS pandemic has had a tremendous impact on global public health.  Despite the development of highly active anti-retroviral therapy, which significantly slows the progression of HIV, HIV/AIDS continues to pose a significant health concern; its effects on the immune system leave individuals with active AIDS at increased risk for colonization by opportunistic pathogens.  To address this, AIDS patients have traditionally relied upon curative and prophylactic antibiotics to treat and prevent infection, respectively.  However, the use of antibiotics exerts a selective pressure against drug-sensitive microbial strains, thus bolstering the evolutionary fitness of drug-resistant strains by allowing them to persist without competition.  When this occurs, resistant strain dominance can threaten the efficacy of both targeted and prophylactic antimicrobials, thereby creating health risk for both immunocompetent and immunocompromised hosts.             Although mathematical modeling has been used to study the emergence of antibiotic resistance in a variety of settings, the question of how the microbial evolutionary landscape is changed by a highly immunocompromised host population has not been addressed. My research uses compartmental epidemiological modeling to examine the evolutionary effects of changes in the prevalence and fitness of drug-sensitive and drug-resistant pathogens due to antibiotic use in highly AIDS-affected regions.  I apply an SEIR model to study the means by which collective host immunosuppression creates a novel environment for the emergence and maintenance of drug-resistant bacterial pathogens. Broadly, I address three questions.:  First, I examine the immune status-based differences in relative contribution to the emergence of antibiotic resistance when curative antibiotic adherence is varied among the actively AIDS-immunocompromised. Second, holding HIV/AIDS prevalence constant, and varying percent antibiotic prophylaxis treatment among HIV/AIDS patients, I analyze the risks and benefits of prophylaxis use.  (Although prophylactic use prevents opportunistic infection, it potentially selects for the emergence of antibiotic resistance at the same time.)  Third, I vary the prevalence of prophylactic antibiotic and resistant strain fitness to analyze the condition-dependent differences in the evolutionary success of drug-resistant and drug-sensitive pathogen strain
A multiscale computational approach to study RNase A catalysis
Creators: name: Dissanayake Rallage, Thakshila D.
Publisher: name: No Publisher Supplied
Year: 2016

description: Enzyme catalysis is an extremely important and complex process that is  fundamental to biology.  Experiments provide a wealth of valuable  information about the function of enzymes; however, this information  requires the use of computational models to establish a meaningful  interpretation that can be used to guide design.  Multiscale  computational models, which integrate a hierarchy of theoretical  methods to address complex biomolecular problems that span large  spatial and temporal ranges, afford powerful tools to provide a  detailed molecular level interpretation of a wide range of  experimental data from which a consensus view of catalytic mechanism  may emerge.  In this dissertation, I detail my efforts to develop and  apply multiscale methods to study the mechanisms of RNA backbone  cleavage catalyzed by Ribonuclease A, an important archetype enzyme  system, and the factors that regulate its activity.  In the first phase of this research, I use molecular dynamics  simulations to characterize the structure and dynamics of the active  enzyme in solution at different stages along the reaction path.  In  this work, I demonstrate that the crystallographic structure  represents an inactive, catalytically non-relevant state, and make  predictions that a conformational change involving the flipping of the  side chain of a conserved histidine residue (His12) is required to  adopt a catalytically competent conformation.  In the second phase of this research, I apply ''constant pH molecular  dynamics simulations'' (CpHMD) to characterize the conditional probability of  finding key active site residues in a protonation state that supports  general acid-base catalysis.  This allowed the prediction of pKa  shifts for His12, His119 and Lys41, and, for the first time,  activity-pH profiles for an enzyme system that can be compared  directly with those measured in kinetic experiments.  In the third phase of this research, I use combined quantum  mechanical/molecular mechanical methods to study the catalytic  chemical steps of transphosphorylation.  Results of  this work predict a free energy landscape for the reaction, from which  the minimum free energy pathway that connects reactants and  products allows a detailed molecular-level picture of mechanism.  In the fourth phase of this research, I extend the CpHMD method to  nucleic acid systems, to benchmark the method for the study of  ribozymes that catalyze the same reaction as RNase A.
Trichomyia spinosa Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia spinosa

description: Trichomyia spinosa Araújo & Bravo sp. nov.
(Figs. 43A–F)
Diagnosis. Membranous expansion on gonocoxite, covering the projection of aedeagal complex and aedeagus; arm of gonocoxite pilose with apical spur-like setae directed distally; gonostylus reduced, 0.3 times the length of projection of aedeagal complex; ejaculatory apodeme 3.5 times the length of gonostylus; cercus with a row of rodlike setae.
Description. Male. Head subcircular in frontal view. Antenna incomplete in the studied specimens; scape and pedicel subspherical; flagellomeres pyriform and eccentric (Fig. 43A); ascoids lost. Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.7:0.7 (Fig. 43B). Wing. Bases of R4+5 and r-m unsclerotized, m-cu absent (Fig. 43C). Male terminalia: Hypandrium and gonocoxites fused with a membranous expansion, covering projection of aedeagal complex and aedeagus. Arm of gonocoxite pilose and directed to the apex with about three spur-like apical setae. Gonostylus reduzed, 0,3 times the length of projection of aedeagal complex, ovalar, slightly sclerotized, articulated ventrally to gonocoxite. Aedeagal complex with one lanciform pair of sclerotized projections with tips divergent. Aedeagus ending near apex of projections in the aedeagal complex. Parameres fused forming a cuneiform structure (Fig. 43F). Ejaculatory apodeme 3.5 times the length of gonostylus. Epandrium pilose, wider than long. Cercus pilose and piriform, with a row of about eight rodlike setae (Fig. 43D). Hypoproct with apical micropilosity (Fig. 43E).
Female. Unknown.
Material examined. Brazil, Amazonas, Manacapuru, Cajatuba, Km 69/3, 06.. X.1998, holotype ♂, without name of collector (MZFS); 16 paratypes: 2 ♂, same locality, date and collectors as holotype (MZFS); 6 ♂, same locality as holotype, 20.IV.1998, RQ, RN, PE leg. (INPA); 3 ♂, same locality as holotype, 13.X.1998, without name of collector (MZFS); 2 ♂, same locality as holotype, 21.IV.1998, RQ, RN, PE leg. (MZFS); 1 ♂, same locality as holotype, Km 75, 25–27.VII.1997, without name of collector (INPA); 1♂, Pará, Novo Repartimento, Vic. Bandeirante, Ramal dos sem terra, 22.VIII.1998, without name of collector (MZFS); 1♂, Rondônia, Cacaulândia, 200Km SSE of Porto Velho, 25. V–06.VI. 998 L. W. Quate (MZFS)
Etymology. From Latim, spinosus = provided with spines, refers to the presence of thick bristles, spines-like, in ventral view of cercus.
Distribution. Brazil—Amazonas, Pará, Rondônia.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on pages 70-71, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Microbial safety of unpasteurized juice
Creators: name: Sapit, Diane
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2015

description: Most cold-pressed juice companies choose not to pasteurize their fruit and vegetable juice. The use of high heat in pasteurization destroys heat-sensitive vitamins and nutrients and inactivates beneficial digestive enzymes. Companies that sell unpasteurized juice mainly do so in order to preserve as much of the nutritional value of the juice as possible. However, unpasteurized juice has a greater risk of contamination by pathogenic microorganisms. In lieu of pasteurization, some cold-pressed juice companies use high-pressure processing which keeps most of the vitamins and nutrients intact while still ensuring the microbiological safety of the juice. Those who want to consume juice that both maximize safety and nutritional content should consider purchasing the high pressure processed cold-pressed juice.
description: increasing consumer awareness of the pathogenic risks of unprocessed fruit and vegetable juice
"But I don't want to get a shot!"
Creators: name: Mohammed, Aliyah
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2015

description: For both children and their parents, going to the doctor can be a stressful experience. Parents are unsure of what to tell their children and may not adequately prepare the child prior to a doctor’s visit. Doctors could educate parents on what information should be provided to the child based on their age making future visits less stressful and a more pleasant experience. Fostering a good doctor/patient relationship early on will promote healthy lifelong habits.
description: De-stressing doctor's visits for children through parent education
Twitter: an ideal platform for delivering educational material in today's world
Creators: name: Matyash, Michelle
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2015

description: Twitter is an ideal platform for delivering educational material in today’s world.  With twitter, educators can extend their classroom beyond its walls providing a unique learning experience to both their students and students around the world.  Anyone with a twitter account can gain access to information tweeted by educators on various topics anytime, anyplace. As an example of how educational information can be twitterized and delivered to the masses, we chose to break down information into tweets on what pet owners should do to prepare for their pets for emergencies.
description: How Educators Should Engage and Educate the General Population
Something fishy with whaling treaties
Creators: name: Colon, Jose
name: Shapiro, Chaim
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2015

description: Whaling has been an important industry for some cultures over thousands of years. However, whaling has continued to a point where entire species are now threatened or endangered. In 1982, the International Whaling Commission announced a moratorium on commercial whaling until the populations could recover. However, this moratorium has not stopped all countries from whaling. Certain countries have claimed to whale under the guise of scientific research, but in actuality have been commercially whaling.  To prevent exploitation of these loopholes, stricter regulations should be imposed on these countries to ensure that scientific whaling is used for research only. In response to this, we proposed a new law that would close this loophole. We put up a petition on Change.org and sent the petition and our proposed “Red Tag” law to the International Whaling Commission and organizations that serve to protect whales and our oceans.
description: Imposing stricter international regulations on "scientific" whaling" proposal for a "red tag" program for whales
Displays of animal altruism
Creators: name: Sukkar, Ismail
name: Tsen Jing Wei, Leslie
name: Weinberger, Adam
name: Fagan, Julie M.
Publisher: name: No Publisher Supplied
Year: 2015

description: Under the law, animals are considered property; no higher than inanimate objects. However, animals show altruistic behavior and therefore animals should be considered, not “property” but “living property”.  We compiled numerous videos about animal exhibiting altruistic behaviors, and published the compilation on YouTube. We then linked the video to a petition that upgrades animals’ legal status to living property.
description: Another reason why animals should be considered living property
QualidataNet – das Netzwerk für Management, Data Sharing und Nachnutzung qualitativer Forschungsdaten
Creators: name: Mozygemba, Kati
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Qualitative Research
subject: Data Management
subject: qualitative data, data sharing, research data management, Forschungsdatenmanagement, qualitative Forschung, research data, QualidataNet, search portal, metadata

description: Als „central point of entry“ bündelt QualidataNet Informationen über Forschungsdaten und Angebote unterschiedlicher Archivierungsinfrastrukturen. Das Netzwerk hilft Ihnen, geeignete Archivierungspartner zu finden und informiert zu Themen des Managements, des Zugangs und der Nachnutzung qualitativer Forschungsdaten.
Motion of viscous liquids and air bubbles in narrow gaps under high gravity
Creators: name: Dutt, Saugata
Publisher: name: No Publisher Supplied
Year: 2016

description: Removal of entrapped air bubbles is generally the rate-limiting step in the conventional bonding of laminates. This thesis describes a new technique to bond laminates together by using centrifugal acceleration to drive a liquid adhesive between laminates and remove initially entrapped air bubbles. The authors studied the effect of “high gravity” (~50 g’s generated using a centrifuge) on air bubbles sandwiched in a 100-micron gap. Some of the bubble diameters were larger than the gap between the laminates (factors ranging from 5 to 80), which meant there was significant variation of air bubble shapes due to the walls of the gap. The drag on the bubbles came from both the walls and the surrounding liquid, and these sandwiched bubbles traveled more slowly than theoretical spherical equivalents in an unconstrained medium. Comparisons between experimental drag on the flattened bubbles and theoretical drag on spherical equivalents show that the bubbles studied had significant increases in coefficients of drag – factors ranging from nearly 2 to 280. In addition to studying the motion of air bubbles in a narrow gap, this work provides the experimental protocol to laminate thin transparent sheets together with liquid adhesive. Using this protocol with modest centrifugal acceleration, it was possible to remove bubbles from the gaps with 5 minutes of spinning. This process has the potential to become an effective manufacturing method for laminating various types of components to each other, such as sheets of polyethylene terephthalate (PET), polymethylmethacrylate (PMMA), or ultra-thin glass used in touchscreens or stacked laminates in transparent, impact-resistant windows.
Amyttopsis forcipata Beier 1965
Creators: name: Naskrecki, Piotr
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Amyttopsis
Amyttopsis forcipata

description: Amyttopsis forcipata Beier 1965
Known only from the type locality in the Democratic Republic of Congo (“ Kongo ”) (Beier 1965). Material examined. DEMOCRATIC REPUBLIC OF CONGO: 74 mi. NE of Tshikapa (5°37'S, 20°1'E), 9.viii.1957, coll. E. S. Ross & R. E. Leech - 2 males (incl. holotype) (CAS).
description: Published as part of Naskrecki, Piotr, 2008, New species of arboreal predatory katydids from West Africa (Orthoptera: Tettigoniidae: Meconematinae), pp. 1-28 in Zootaxa 1732 on page 8, DOI: 10.5281/zenodo.181351
Hormone therapy in precision medicine: a preclinical exploration of interactions between tibolone, sex, and gonadal hormone deprivation in the brain
Creators: name: McGovern, Andrew Joseph
Publisher: name: University of Limerick
Year: 2025
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences

description: Neurological diseases often impact females more significantly than males, with sex hormone fluctuations, such as those occurring during menopause, playing a substantial role. Despite known connections, the mechanisms through which sex hormones influence brain function and their modulation by hormone therapies like Tibolone remain insufficiently explored. This thesis aims to address these knowledge gaps by investigating the interactions between biological sex, gonadal hormone deprivation, and Tibolone in the murine prefrontal cortex (PFC)—a region both vulnerable to neurodegenerative diseases and responsive to sex hormone action.Utilizing a murine model, male and female mice were subjected to gonadectomy, followed by acute Tibolone treatment. Comprehensive proteomic analyses of the PFC were conducted to identify changes in the protein landscape influenced by sex, gonadectomy, and Tibolone. Findings reveal that biological sex and the presence or absence of gonadal hormones significantly alter Tibolone's impact on key pathways, including mitochondrial metabolism, oxidative phosphorylation, and synaptic function. Differential protein expression patterns highlight the complex regulatory roles of sex hormones and their interactions with Tibolone, which impact neurodegeneration-related pathways.Proteomic data further demonstrated that sex and gonadal status modulate the efficacy of Tibolone in neurodegenerative contexts. Key proteins involved in mitochondrial function, such as NDUFA2, NDUFA7, and UQCR10, showed significant sex-specific alterations, indicating that mitochondrial bioenergetics may underlie observed sex differences in neurodegenerative disease susceptibility. Additionally, geometric analyses confirmed sex-specific Tibolone responses, suggesting proteomic convergence following gonadal hormone deprivation.This work underscores the critical role of sex-specific factors in hormone therapy outcomes and advocates for precision medicine approaches tailored to individual hormonal profiles. While focused on the PFC, the findings provide valuable insights into hormone therapy mechanisms, with implications for developing effective sex-specific interventions for neurodegenerative diseases.
Amyttopsis vinculata Beier 1965
Creators: name: Naskrecki, Piotr
Publisher: name: Zenodo
Year: 2008
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Orthoptera
Tettigoniidae
Amyttopsis
Amyttopsis vinculata

description: Amyttopsis vinculata Beier 1965
Recorded by Beier (1965) from Ghana, Cameroon, and Equatorial Guinea (Fernando Poo).
Material examined. CAMEROON: Johann Alberchtshohe, 25.i.1896, coll. L. Conradt - 1 male (holotype) (ZMHB); GHANA: Ashanti, near Naraume, 14.viii.1957, coll. N.D. Jago - 1 male (paratype) (BMNH).
description: Published as part of Naskrecki, Piotr, 2008, New species of arboreal predatory katydids from West Africa (Orthoptera: Tettigoniidae: Meconematinae), pp. 1-28 in Zootaxa 1732 on page 8, DOI: 10.5281/zenodo.181351
A joint framework for object recognition
Creators: name: El-Gaaly, Tarek
Publisher: name: No Publisher Supplied
Year: 2016

description: Visual object recognition is a challenging problem with a wide range of real-life applications. The difficulty of this problem is due to variation in shape and appearance among objects within the same category, as well as varying viewing conditions, such as viewpoint, scale, illumination, occlusion and articulation of multi-part deformable objects. In addition, beyond the visual spectrum, depth and range sensors suffer from noise that inhibits object recognition. Under visual object recognition lie three subproblems that are each challenging: category recognition, instance recognition and pose estimation. Impressive work has been done in the last decade on developing systems for generic object recognition. Previous research has covered many recognition-related issues, however, the problem of multi-view recognition remains among the most fundamental challenges in computer vision. In this dissertation we focus on discovering low-dimensional latent representations that enable efficient joint multi-view object recognition over multiple modalities. These discovered latent representations allow us to work in lower dimensional latent spaces that capture the factors needed for object recognition from multi-view images and over multiple modalities; from images to depthmaps and 3D point clouds. Each of the models we present in this dissertation explore a different representation space of latent factors. The first model builds multiple kernel induced spaces to fuse information between different modalities and performs object pose estimation in a regression framework. The second model performs manifold analysis to solve categorization and pose estimation simultaneously. It does this by factorizing the space of topological mappings between a unified conceptual manifold and feature spaces. We present two variations of this; an unsupervised learning model and a supervised learning model. The third approach analyzes the representational spaces of the layers of Convolutional Neural Networks and builds on the findings by proposing a network that jointly solves category and pose. The fourth approach explores solving pose-invariant categorization of multi-part objects by shape information, in the form of 3D point clouds. We build a representation that inherently encodes pose and allows objects to be represented by multiple levels of object-part decompositions for more robust object recognition. In each approach we support our hypotheses by extensive experimentation.
Ceroctis capensis
Creators: name: Bologna, Marco A.
name: Amore, Valentina
name: Pitzalis, Monica
Publisher: name: Zenodo
Year: 2018
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Meloidae
Ceroctis
Ceroctis capensis

description: Ceroctis capensis species group
Until now only C. capensis can be referred to this assemblage, apparently endemic to southen Africa.
Ceroctis capensis (Linné, 1767) (Fig. 3K)
Meloe capensis Linné, 1767
Distribution. Southwestern Namibia (new species for this country) and South Africa.
Material examined. [Karas] Lüderitz: Aus, 26.6667°S 16.2667°E (SMWN). Karasburg: 30 mil SE Keetmanshoop (AMNH).
Remarks. Types of this species were not examined.
It is phenetically very distinct from all others species of the genus because of the elytral pattern. Some South African specimens from southern Karoo, Eastern Cape and Free State have red-orange rather than yellow colouration of elytra; the taxonomic value of this form needs morphological and molecular studies.
description: Published as part of Bologna, Marco A., Amore, Valentina & Pitzalis, Monica, 2018, Meloidae of Namibia (Coleoptera): taxonomy and faunistics with biogeographic and ecological notes, pp. 1-141 in Zootaxa 4373 (1) on page 55, DOI: 10.11646/zootaxa.4373.1.1, http://zenodo.org/record/1151722
MOESM8 of Increased lipid production by heterologous expression of AtWRI1 transcription factor in Nannochloropsis salina
Creators: name: Kang, Nam
name: Kim, Eun
name: Kim, Young
name: Bongsoo Lee
name: Won-Joong Jeong
name: Byeong-Ryool Jeong
name: Chang, Yong
Publisher: name: Figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Computational Biology

description: Additional file 8: Figure S5. Carbon fixation and lipid synthesis pathway.
Trichomyia stangae Araujo & Bravo, sp. nov.
Creators: name: Araújo, Maíra Xavier
name: Bravo, Freddy
Publisher: name: Zenodo
Year: 2016
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Psychodidae
Trichomyia
Trichomyia stangae

description: Trichomyia stangae Araújo & Bravo sp. nov.
(Figs. 44A–F)
Diagnosis. Gonocoxite with basal subtriangular expansion, and one arm, thinner, curved with rounded apex; one pair of projections in the aedeagal complex convergents that join apically, with mediolateral bristles and two setulae apically; ejaculatory apodeme short, as long as gonostylus.
Description. Male. Head subcircular in frontal view. Antenna incomplete in the studied specimens; scape subcylindrical and pedicel subspherical; basal flagellomeres pyriform and centric (Fig. 44A); ascoids 1.4 times as long as the length of flagellomere. Palpus three segmented; first segment with sensilla in depressed pit on medial surface; palpus formula 1.0:0.6:0.7 (Fig. 44B). Wing. R4+5 with base unsclerotized; r-m unsclerotized and m-cu absent (Fig. 44C). Male terminalia: Hypandrium and gonocoxites fused with basal subtriangular expansion. One arm of gonocoxite, expanded at the base, curved, with mediolateral bristles and two setulae apically. Gonostylus slightly sclerotized, articulated ventrally to gonocoxite, bare, curved and subtriangular. Presence of one pair of projections in the aedeagal complex convergents that join apically. Aedeagus bifid truncated apically (Fig. 44F). Ejaculatory apodeme short, the same length as gonostylus. Epandrium subquadrangular, with rounded apex. Cercus digitiform with long hairs in lateral view (Fig. 44D) Hypoproct with apical micropilosity (Fig. 44E).
Female. Unknown.
Material examined. Brazil, Amazonas, Presidente Figueiredo, Pitinga, 04.XII.1998, holotype ♂, RQ, LMC leg. (MZFS); 8 paratypes: 2 ♂, same locality, date and colectors as holotype (INPA) 1 ♂, Amazonas, Manacapuru, Cajatuba, Km 69/3, 9.X.1998, without name of collector (MZFS); 1 ♂, Amazonas, Manacapuru, Cajatuba, Km 69/ 3, 6.X.1998,, without name of collector (MZFS); 1 ♂, Pará, Bragança, Estrada para malhado, Com. Jararaca, Km 20, 07.X.1998, without name of collector (MZFS); 1 ♂, Pará, Bragança, Estrada para Monte Alegre, Sítio Boa Esperança, Km17, 28.IX.1998, RF, RBN, FLS leg. (MZFS); 1 ♂, Amazonas, Manaus, Reserva Ducke, 26– 31.VIII.2011, M.X. Araújo (INPA), 1 ♂, Roraima, Km4, São Luiz do Anauá, Fazenda Zulmira, 4.II.2004, M. Rocha leg. (INPA)
Etymology. Named in honor of Dorothy Stang, missionary, sustainable development defender in the Amazon rainforest.
Distribution. Brazil—Amazonas, Pará, Roraima.
description: Published as part of Araújo, Maíra Xavier & Bravo, Freddy, 2016, Description of fourty four new species, taxonomic notes and identification key to Neotropical Trichomyia Haliday in Curtis (Diptera: Psychodidae, Trichomyiinae), pp. 1-76 in Zootaxa 4130 (1) on page 71, DOI: 10.11646/zootaxa.4130.1.1, http://zenodo.org/record/262717
Application of seismic surface-waves in concrete bridge-deck evaluation
Creators: name: Fetrat, Farhad
Publisher: name: No Publisher Supplied
Year: 2016

description: Accurate and timely condition assessment of bridge decks is essential for economic management of aging highway bridges. The ability to evaluate concrete modulus profile in a bridge deck can help the detection of early signs of deterioration and optimize the bridge maintenance procedures. This study presents a new method for modulus profiling of concrete bridge decks. The stiffness matrix method is used to simulate wave propagation in a layered media. The results are compared to numerical finite element models. Dispersion analysis is done using the multi-channel analysis of surface waves (MASW) and phase-shift methods. The characteristics of dispersion surface are analyzed and the effects of model parameters on dispersion surface are examined through a series of parametric studies. An inversion technique is proposed for a fast inversion of surface-wave data collected on bridge decks. This technique utilizes a database of pre-calculated dispersion surfaces and takes advantage of the observed patterns in the parametric study as a priori information for the inversion process.
Chinese seed firm's lobbying activity on biotechnology
Creators: name: Fu, Yuejia
Publisher: name: No Publisher Supplied
Year: 2016

description: Induced institutional innovation could provide more technological advantages, but it calls for government’s support as well as the demand for change from interest groups. It has been proved that some seed firms have profited from bacillus thuringiensis (Bt) crops. Thus, it is reasonable to believe that Chinese seed firms should have positive profit expectation in biotech crops and the motivation to lobby for biotechnology in order to benefit from preferred policies. This thesis examines (1) Did Chinese seed firms lobby for biotechnology? (2) What are the key factors that affect Chinese seed firms’ lobbying activity towards biotechnology?  The analysis was based on a survey data from 50 top Chinese seed firms and following results were generated: (a) firms located in Beijing are more likely to lobby than firms that locate outside of Beijing; (b) State-owned firms are more likely to lobby than private seed firms; (c) seed firms who have GM breeding research and development (R&D) have a higher likelihood of lobbying for biotech than firms without GM breeding R&D. (d) Positive attitude of managers towards the adoption of GM crops is positively related to firm’s lobbying activity positively compared to non-positive attitude.   This thesis suggests that if Chinese government wants to generate more supports for biotechnology, the government needs to help seed firms conducting GM R&D and enhance the enforcement of IPR in order to make seed firms be more confident of profiting from GM technology. In addition, if the Chinese government hopes to hear policy-making suggestions from interst groups, government needs to provide more channels for private seed firms to lobby and establish lobbying channels for seed firms located out of Beijing in order to motivate seed firms’ lobbying activity.
The "spiritualization" of Islam in America
Creators: name: Hannini, Daniyah M.
Publisher: name: No Publisher Supplied
Year: 2016

description: This thesis analyzes the way in which American Muslims in the United States have emphasized highly individualized modes of Islamic practice as they integrate into the fabric of American society. A large number of Muslim immigrants arrived in the U.S. at the same time that there was a growing focus on “spirituality” in society. In concert with these trends, U.S. Muslims have increasingly accentuated forms of Islam that give them significant autonomy and that place more emphasis on religious experience than doctrine and formal institutions. The thesis focuses in particular on Hamza Yusuf, the founder of Zaytuna College in Berkely, California. He sought to familiarize American Muslims with highly individualistic modes of Islamic practice by stressing their compatibility with tradition and by seeking to differentiate them from Islamic mysticism (Sufism). To varying degrees, three additional prominent Muslim thinkers, Yasmin Mogahed, Suhaib Webb, and Yasir Qadhi spread similar ideas among the U.S. Muslim population. The concluding chapter highlights how the events of 9/11 have further motivated Muslims to adopt more “spiritualized” forms of Islamic practice that resonated with widespread trends in U.S. society.