cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Barriers and Enablers of Nurse-led Skin Cancer Screening in Rural Australia
Creators: name: https://orcid.org/0009-0002-3705-2843
name: https://orcid.org/0000-0003-0939-6956
Publisher: name: https://ror.org/02stey378
publisherIdentifier: https://ror.org/02stey378
publisherIdentifierScheme: ROR
Year: 2024

description: Australia has among the highest incidence of skin cancer in the world; two out of three people in Australia will have some form of skin cancer by age 70. Those living in regional and rural areas have a higher incidence of skin cancer than their metropolitan counterparts, and yet, the reach of skin cancer services to regional, rural, and remote Australia is limited to non-existent. General Practitioners (GPs) are primarily responsible for opportunistic skin cancer detection, often made difficult by constrains on consult times, further exacerbated by the maldistribution of primary care providers in rural areas. One solution may be to better utilise nurses as primary providers of skin checks in collaboration with these GPs. This study will examine the barriers and enablers of nurse-led skin checks in rural Australia. Semi-structured interviews will be used to assess the perceived barriers and enablers to a nurse-led screening model, from the perspective of the practitioners who deliver these services. If successful, this project will highlight how to improve future implementation of a nurse-led screening model, and better position future skin screening methods for uptake in rural communities.
Supplementary Data For: Scalable Collaborative Software Visualization as a Service
Creators: name: Krause-Glau, Alexander
name: Hasselbring, Wilhelm
Publisher: name: Zenodo
Year: 2022

description: Supplementary Data For: Scalable Collaborative Software Visualization as a Service README.md describes our setup, the execution, and visualization of results. Open the file in a markdown viewer.
EFFECTS OF CHINA PAKISTAN ECONOMIC CORRIDOR ON REGIONAL INTEGRATION AND ECONOMIC GROWTH
Creators: name: Iqtidar Hussain, Guo Ke
Publisher: name: TuEngr Group
Year: 2020
Subjects: Neo-Functionalism
Trade integration
CPEC agreement
Economic integration
Regional cooperation
Pak-China relations
Pak-Iran relations
Central Asia Republics, Sino-Pakistan Agreement.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 3, 11A03O: 1-10
title: The criminal code of the Northern Territory
title: a critical analysis and appraisal of its fundamental principles of criminal responsibility
titleType: Subtitle
Creators: name: Lowndes, John
Publisher: name: Charles Darwin University
Year: 2004

description: Section 31 of the Criminal Code Act 1983 (NT)1 is a unique provision which has no parallel in the common law or in other Australian Code jurisdictions. Its provisions raise a number of fundamental issues relating to general principles of criminal responsibility. The aim of this thesis is to identify those issues and to highlight the problems posed by s 31 and associated provisions of the Code. This thesis offers possible solutions to those problems.Those proposed solutions do not, however, profess to provide definitive answers, but are put forward with a view to stimulating further investigation of those problematical areas of the Code and the ways in which those difficulties might be resolved by legislative action - leading to an improvement of the criminal law of the Northern Territory. Some of the problems with the Code may also exist in other Code jurisdictions. Therefore, the analysis undertaken by this thesis, and the recommendations made therein, have a broader application, and may be of interest to legislators in other jurisdictions. The first issue concerns the jurisprudential construct in which the Criminal Code (NT) operates, with particular emphasis on s 31 which treats the absence of intention or recklessness as a criminal law excuse. The second relates to the operation of s 31 and s 322 (an associated section) as general provisions for criminal responsibility and their application to specific offences, that is, the extent to which they control and govern the scope of specific offences. The third concerns the practical application of ss 31 and 32 to particular offences and involves the marrying of the mental elements in those two sections with the physical elements of an offence. The fourth and final issue concerns the nature and scope of the mental elements prescribed by ss 31 and 32.
‘Wanheibao’: A new polyploid late-season table grape with muscat flavor
Creators: name: Tang, Xiao-Ping
name: Chen, Jun
name: Ma, Xiao-He
name: Dong, Zhi-Gang
name: Zhao, Qi-Feng
name: Li, Xiao-Mei
name: Tan, Wei
name: Wang, Ming
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Research Note
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
‘Zhengmei’: A new early-ripening table grape
Creators: name: Fan, Xiu-Cai
name: Li, Min
name: Zhang, Ying
name: Jiang, Jian-Fu
name: Sun, Hai-Sheng
name: Liu, Chong-Huai
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Research Note
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
EFFECTIVENESS OF GROWTH STIMULANTS IN THE CULTIVATION OF KOREAN RED PINE SEEDLINGS (PINUS DENSIFLORA SIEBOLD ET ZUCC.) IN THE PRIMORSKY KRAI CONDITIONS
Creators: name: V.Yu. Ostroshenko, V.A. Poleschuk
Publisher: name: TuEngr Group
Year: 2020
Subjects: Korean red pine
forest nursery
seedlings
planting material
root-feeding
growth stimulant
Crezacin
Ribav-Extra
Zircon
Ecopin
Epin-Extra

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 3, 11A03D: 1-8
MODERN TECHNOLOGIES AND APPROACHES TO THE TRIANGULATION ALGORITHMS
Creators: name: Vitaly V. Baynev, Sergey A. Fedosin
Publisher: name: TuEngr Group
Year: 2020
Subjects: Delaunay method
modeling, Triangulation network
Delaunay triangulation
Triangulation method.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 3, 11A03E: 1-6
High-Performance Sorting-Based k-mer Counting in Distributed Memory with Flexible Hybrid Parallelism
Creators: name: Li, Yifan
name: Guidi, Giulia
Publisher: name: arXiv
Year: 2024
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: Genomics (q-bio.GN)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: In generating large quantities of DNA data, high-throughput sequencing technologies require advanced bioinformatics infrastructures for efficient data analysis. k-mer counting, the process of quantifying the frequency of fixed-length k DNA subsequences, is a fundamental step in various bioinformatics pipelines, including genome assembly and protein prediction. Due to the growing volume of data, the scaling of the counting process is critical. In the literature, distributed memory software uses hash tables, which exhibit poor cache friendliness and consume excessive memory. They often also lack support for flexible parallelism, which makes integration into existing bioinformatics pipelines difficult. In this work, we propose HySortK, a highly efficient sorting-based distributed memory k-mer counter. HySortK reduces the communication volume through a carefully designed communication scheme and domain-specific optimization strategies. Furthermore, we introduce an abstract task layer for flexible hybrid parallelism to address load imbalances in different scenarios. HySortK achieves a 2-10x speedup compared to the GPU baseline on 4 and 8 nodes. Compared to state-of-the-art CPU software, HySortK achieves up to 2x speedup while reducing peak memory usage by 30% on 16 nodes. Finally, we integrated HySortK into an existing genome assembly pipeline and achieved up to 1.8x speedup, proving its flexibility and practicality in real-world scenarios.
description: 10 pages
A highly efficient embryo rescue protocol to recover a progeny from the microvine
Creators: name: Chatbanyong, R.
name: Torregrosa, L.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The grapevine is a difficult species for genetic studies due to the plant size and long life cycle. With the microvine, these limitations can be overcome thanks to its dwarf stature, continuous flowering, short juvenile phase and generation cycle. The advantages of the microvine allow scientists to undertake genetic studies 2-5 times more rapidly than the current situation with normal grapevines. However, the seeds obtained from microvine parents have a low germination rate, and therefore some approaches to improve seed germination are required. Four microvine lines (ML1, V19, Pico x FLB 225, and AB x ML1) and a classical grapevine variety (‘Syrah’ cl. 174) were experimented in embryo rescue experiments. To evaluate embryo germination rate during berry development, seeds were collected from four different berry developmental stages including 2 weeks before veraison (WBV), veraison, 3 and 6 weeks after veraison (WAV). For all microvine varieties, the age of seed or berry stage influenced the development of the embryos. The highest percentage of germinating embryos (100 %) and normal developed plantlets (100 %) were recorded at veraison stage followed by 2 WBV, 3 WAV and 6 WAV, respectively. In addition, growth and development of embryos derived from veraison berries were also faster than the other phases. This study concluded that veraison is the most suitable berry developmental stage for microvine embryo extraction and culture, whereas, the best stage for embryo rescue in ‘Syrah’ grapevine is 2 WBV. The information obtained from this experiment will be useful for microvine breeding programs and expand their germplasm base in the future.
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
Combined mixture-process variable approach: a suitable statistical tool for nanovesicular systems optimization
Creators: name: Basant A. Habib
name: AbouGhaly, Mohamed H. H.
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Pharmacology
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Objectives: This study aims to illustrate the applicability of combined mixture-process variable (MPV) design and modeling for optimization of nanovesicular systems. Methods: The D-optimal experimental plan studied the influence of three mixture components (MCs) and two process variables (PVs) on lercanidipine transfersomes. The MCs were phosphatidylcholine (A), sodium glycocholate (B) and lercanidipine hydrochloride (C), while the PVs were glycerol amount in the hydration mixture (D) and sonication time (E). The studied responses were Y1: particle size, Y2: zeta potential and Y3: entrapment efficiency percent (EE%). Polynomial equations were used to study the influence of MCs and PVs on each response. Response surface methodology and multiple response optimization were applied to optimize the formulation with the goals of minimizing Y1 and maximizing Y2 and Y3. Results: The obtained polynomial models had prediction R2 values of 0.645, 0.947 and 0.795 for Y1, Y2 and Y3, respectively. Contour, Piepel’s response trace, perturbation, and interaction plots were drawn for responses representation. The optimized formulation, A: 265 mg, B: 10 mg, C: 40 mg, D: zero g and E: 120 s, had desirability of 0.9526. The actual response values for the optimized formulation were within the two-sided 95% prediction intervals and were close to the predicted values with maximum percent deviation of 6.2%. Conclusions: This indicates the validity of combined MPV design and modeling for optimization of transfersomal formulations as an example of nanovesicular systems.
Anion-dependent structural diversity of cadmium(II) complexes: synthesis, crystal structures, luminescence properties, and unusual C-H/σ supramolecular interactions involving σ-aromatic M2X2 cores
Creators: name: Barman, Nikita
name: Saikat Banerjee
name: Brandão, Paula
name: Bauzá, Antonio
name: Frontera, Antonio
name: Saha, Amrita
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology
subject: Inorganic Chemistry

description: Four complexes based on N,N′-bis(2-pyridylmethylene)-1,3-propanediamine (L) and different Cd(II) salts have been synthesized and characterized by single-crystal X-ray diffraction analysis. The complexes are [Cd2(L)2(μ-Cl)2](ClO4)2 (1), [Cd2(L)2(μ-Br)2](ClO4)2 (2), [Cd(L)I](ClO4) (3), and [Cd(L)(NCS)2] (4). L exhibits the same coordination mode in 1–4. The radius of each anion plays a role in affecting the structures and luminescent intensities of the final products. CdCl2, CdBr2, and CdI2 react with L to produce chloride or bromido-bridged binuclear complexes and mononuclear iodido complex, respectively, whereas an unusual mononuclear trigonal prismatic (TP) 4 is obtained when thiocyanate was used as a coligand. Photoluminescence properties of all the complexes show that the trend of fluorescence intensity is 1 > 4 > 2 > 3. All four complexes exhibit different supramolecular interactions such as C–H/σ, π–π, and C–H/π and hydrogen bonding interactions. The experimental findings are complemented by density functional theory (DFT) calculations.
Genetic and protein sequence variation of CBF1-4 in cold hardy wild grapevine germplasm
Creators: name: Londo, J. P.
name: Garris, A. J.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Grapevine (Vitis vinifera) production is limited by a wide array of abiotic stresses including cold, drought, and salinity stresses. The regulation of stress response genes under these conditions is very complex but a common and essential component of the gene network is the C-Repeat Binding Factor (CBF) genes. Four unique CBF genes have been described in grapevine to date and gene or protein level variation may help explain differences in stress resistance phenotypes in grapevine. This study was conducted to evaluate the level of genetic diversity found at these genes in different wild grapevine species as well as in a panel of cultivated grapevine varieties. Examination of the genetic variation at the four CBF genes in grapevine revealed high sequence variation with many different alleles in wild and cultivated grape. However, predicted protein sequence variation of the different genes revealed a different pattern. Vitis CBF genes 1, 2, and 3, which play roles in the stress response to many different stresses, were seen to have high levels of protein sequence variation. In contrast, VCBF4, which is induced by cold, was seen to have very little variation across all wild and cultivated grapevine samples. This contrasting pattern between different gene family members suggests an essential role of VCBF4 in grapevine as the protein sequence is highly conserved between wild North American grapevine species and cultivated varieties.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 4 (2014): Vitis
In vitro conservation of native Chinese wild grape (Vitis heyneana Roem. & Schult) by slow growth culture
Creators: name: Pan, Xue Jun
name: Zhang, Wen E.
name: Li, Xia
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The aim of the present research work was to develop a protocol to preserve Chinese wild grape by slow growth conservation. Spectacular success was achieved in preserving shoot apices of Vitis heyneana under slow growth conditions. The optimized nutrient formulation to maintain slow growth of cultures was Murashige and Skoog (MS) media contained 5 g∙L-1 agar, 0.05 mg∙L-1 indole-3-butyric acid (IBA) and 0.1 mg∙L-1 indole acetic acid (IAA) and 0.5 mg∙L-1 abscisic acid (ABA). The best osmotic adjustment of nutrient medium was achieved by employing 10 g∙L-1 mannitol where 47.78 % cultures could be conserved up to 12 months without any subculture. Among different combination of air breathable film area (ABFA), light intensity and chlorocholine chloride (CCC) concentration, used for increasing the subculture period, 19.63 mm2 ABFA with 5.0 g∙L-1 CCC cultured under lower light intensity suited best for slow growth conservation with 48.00 % microplants were able to survive 10 months without subculture. Further tests showed that the CCC had a negative effect to grape conservation. Cultures responded better when incubated at 10 °C compared with the control (25 °C). Our study also found that the combination of factors were also more beneficial to grape conservation than that of a single factor. 100 % survived shoots by slow growth conservation could regenerate to normal plantlets and transplant successfully. Transplanting plantlets showed no obvious difference in morphology with the control and the maternal parent in the field.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 4 (2014): Vitis
Rootstock and seasonal variations affect anthocyanin accumulation and quality traits of ‘Kyoho’ grape berries in subtropical double cropping system
Creators: name: Chou, Ming-Yi
name: Li, Kuo-Tan
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The double cropping system has been commercially adopted in subtropical viticulture regions. However, very limited information about rootstock and seasonal effects on berry quality traits are available for this unique production system. Developing ‘Kyoho’ berries from own-rooted vines and from vines on 5C and 1202C rootstocks were periodically sampled from veraison until harvest in two consecutive cropping cycles to document the potential seasonal influence on rootstock effects. Anthocyanin concentration in berry skin, total soluble solids content (TSS), and titratable acidity (TA) were analyzed. In both cropping cycles, own-rooted vines produced berries with the highest anthocyanin concentration while vines on 1202C produced berries with the lowest anthocyanin concentration among the three scion/rootstocks. Anthocyanin concentrations were not differentiated by the differential climate pattern between the summer and the winter cropping cycles. Berries of own-rooted ‘Kyoho’ and ‘Kyoho’/5C vines accumulated satisfactory and equal amount of TSS in both cropping cycles. 1202C rootstocks did not affect berry TSS in the summer cropping cycle but reduced TSS in the winter cropping cycle. Significant rootstock and seasonal effects on berry TA were detected. Own-rooted vines produced berries with the lowest TA while vines on 1202C produced berries with the highest TA among the three scion/rootstock combinations. TA of berries from the winter cropping cycle was significantly higher than that from the summer cropping cycle especially in ‘Kyoho’/1202C. Relationships between anthocyanins and TSS of developing berries after veraison properly fitted into a sigmoidal function regardless of rootstocks and cropping cycles. However, the duration of the initial lag phase, the onset and the trend of both quality triats in the increasing phase, and the presence and degree of the final lag phase in the relationship were all modulated by rootstocks and by seasonal variations.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 4 (2014): Vitis
Gutiérrez, Gustavo: Theologie der Befreiung (1971/2021). Der bleibende Impuls eines theologischen Klassikers hg. v. Michelle Becka / Franz Gmainer-Pranzl
Creators: name: Senft, Josef
Publisher: name: Theologische Revue
Year: 2022

description: Theologische Revue, Vol. 118 (2022): April
LEGAL AND PHILOSOPHICAL VIEWS OF G.F. SHERSHENEVICH: A RUSSIAN SCIENTIST AND POLITICIAN
Creators: name: Gennady S. Pratsko, Julia I. Isakova
Publisher: name: TuEngr Group
Year: 2020
Subjects: Gabriel Feliksovich Shershenevich
Philosophy of law
General theory of law
Russian theory of law
Russian theoreticians of law
Methodology of law.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 3, 11A03I: 1-7
The annual growth cycle of grapevines in Southern Finland
Creators: name: Karvonen, J.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The aim of this study was to investigate whether grape growing is possible in the southernmost areas of Finland, in the Helsinki-Vantaa area (Tuusula parish, lat. 60°24ʹ10ʹʹN, long. 25°25ʹ45ʹʹE). The annual growing cycle of grapevines, with some climate parameters, was monitored over ten years (2002-2011). The growth cycle of grapevines from bud break to harvest was 138 (± 9) days, the growing season 198(±18) days, the temperature sum 1608 (± 131) °C days (GDD, basic + 5 °C) and 794 (± 121) °C days (basic +10 °C), the number of sunshine hours 1447 (± 117) h, and the solar energy 2904 (± 127) MJ/m². Dependence was calculated between some essential growth factors by statistical analyses. According to the results it can be concluded that, under existing weather conditions, grape growing is possible in southernmost Finland, although it will be necessary to find or further develop varieties adapted to the northern cool climate and to identify regions with an optimal microclimate for growing grapes.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 4 (2014): Vitis
Ottersbach, Stefan: Christliche Freude als Glück? Transversal-weltentheologische Erschließung eines kulturellen und christlichen Leitthemas für eine zukunftsfähige Pastoral
Creators: name: Burke, Andree
Publisher: name: Theologische Revue
Year: 2022

description: Theologische Revue, Vol. 118 (2022): April
Gutmann, David / Peters, Fabian: #projektion2060. Die Freiburger Studie zu Kirchenmitgliedschaft und Kirchensteuer: Analysen - Chancen – Visionen
Creators: name: Sellmann, Matthias
Publisher: name: Theologische Revue
Year: 2022

description: Theologische Revue, Vol. 118 (2022): April
Ameliorative effects of salicylic acid on mineral concentrations in roots and leaves of two grapevine (Vitis vinifera L.) cultivars under salt stress
Creators: name: Amiri, J.
name: Eshghi, S.
name: Tafazoli, E.
name: Kholdebarin, B.
name: Abbaspour, N.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Salicylic acid (SA) acts as an endogenous signal molecule, synchronizing plant responses under abiotic stress and a component of tolerance in plants. The current study investigates the effects of SA on mineral nutrient concentrations in two grapevine (Vitis vinifera L.) cultivars, 'Qarah Shani' and 'Thompson Seedless' under NaCl stress. Grapevine rooted cuttings were planted in pots, containing a mixture of perlite and cocopeat (1:1 v/v) and placed in an open hydroponic system. Plants were exposed to five levels of salinity 0, 25, 50, 75 and 100 mM NaCl and four levels of SA 0, 100, 200 and 300 mg∙L-1. Results indicated that foliar spray with SA improved nutrient uptake by grape roots. Plant’s leaves and roots Na+ and Cl- contents increased significantly, and NO- 3-N, K+, Na+, Ca2+, Mg2+, Zn2+, Fe2+ and also K+/Na+ selectivity ratios decreased in both cultivars in response to salt treatments. Application of SA significantly reduced Na+ and Cl- accumulation in leaves and roots in both cultivars and it increased NO3-N, K+, Ca2+, Mg2+, Zn2+ and Fe2+ contents under NaCl stress. Therefore, SA could mitigate the detrimental effects of salinity on accumulation of harmful ions and improve the absorption of essential and beneficial elements in grapevine under salinity.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 4 (2014): Vitis
Leaf area reduction by trimming, a growing technique to restore the anthocyanins : sugars ratio decoupled by the warming climate
Creators: name: Martinez De Toda, F.
name: Sancha, J. C.
name: Zheng, W.
name: Balda, P.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The aim of this work is the evaluation of the leaf area reduction by trimming, as a growing technique to restore the anthocyanins : sugars ratio decoupled by the warming climate. A 3-year period (2010-2012) severe shoot trimming treatment was done after berryset (berry diameter 3-4 mm) and the veraison date was delayed around 20 days. The grapes were picked at the same level of soluble solids in all the treatments. However, for every year, the trim treatment significatively increased the total anthocyanin content between 8 % and 21 % compared to control. Therefore, delaying the berry ripening process trough the decrease of the leaf area to fruit ratio, could partially restore the anthocyanins : sugars ratio disrupted by elevated temperatures. Although it is necessary to study other trimmings intensities as well as other times of intervention, the shoot trimming treatment could be a very simple technique to delay berry ripening and compensate the effects of climate warming.
description: VITIS - Journal of Grapevine Research, Vol. 53 No. 4 (2014): Vitis
Digital Twin sensors in cultural heritage applications
Creators: name: Niccolucci, Franco
name: Felicetti, Achille
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences
subject: E.1; H.2.3; H.3.1; H.3.2; I.2.4

description: The paper concerns the extension of the Heritage Digital Twin Ontology introduced in previous work to describe the reactivity of digital twins used for cultural heritage documentation by including the semantic description of sensors and activators and all the process of interacting with the real world. After analysing previous work on the use of digital twins in cultural heritage, a summary description of the Heritage Digital Twin Ontology is provided, and the existing applications of digital twins to cultural heritage are overviewed, with references to reviews summarizing the large production of scientific contributions on the topic. Then a novel ontology, named Reactive Digital Twin Ontology is described, in which sensors, activators and the decision processes are also semantically described, turning the previous synchronic approach to cultural heritage documentation into a diachronic one. Some case studies exemplify this theory.
description: Submitted to Sensors (Open Access Journal from MDPI). 17 pages, 3 figures
EFFICIENCY EVALUATION OF LISTED HOSPITAL COMPANIES IN THE CAPITAL MARKET: INTRODUCING A NEW HOSPITAL ADMINISTRATION AND FINANCING
Creators: name: Meghdad Rahati, Iravan Masoudi Asl
Publisher: name: TuEngr Group
Year: 2020
Subjects: Health Management, Management Sciences (Financial Management).

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 3, 11A03L: 1-10
Moraltheologie und Universität. Eine Verhältnisbestimmung, hg. v. Andreas Lob-Hüdepohl / Rupert M. Scheule / Kerstin Schlögl-Flierl
Creators: name: Koller, Edeltraud
Publisher: name: Theologische Revue
Year: 2022

description: Theologische Revue, Vol. 118 (2022): April
Probing the interaction mechanism of small molecule inhibitors with matriptase based on molecular dynamics simulation and free energy calculations
Creators: name: Dong-Ru Sun
name: Zheng, Qing-Chuan
name: Zhang, Hong-Xing
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Cancer

description: Matriptase is a serine protease associated with a wide variety of human tumors and carcinoma progression. Up to now, many promising anti-cancer drugs have been developed. However, the detailed structure–function relationship between inhibitors and matriptase remains elusive. In this work, molecular dynamics simulation and binding free energy studies were performed to investigate the biochemistry behaviors of two class inhibitors binding to matriptase. The binding free energies predicted by MM/GBSA methods are in good agreement with the experimental bioactivities, and the analysis of the individual energy terms suggests that the van der Waals interaction is the major driving force for ligand binding. The key residues responsible for achieving strong binding have been identified by the MM/GBSA free energy decomposition analysis. Especially, Trp215 and Phe99 had an important impact on active site architecture and ligand binding. The results clearly identify the two class inhibitors exist different binding modes. Through summarizing the two different modes, we have mastered some important and favorable interaction patterns between matriptase and inhibitors. Our findings would be helpful for understanding the interaction mechanism between the inhibitor and matriptase and afford important guidance for the rational design of potent matriptase inhibitors.
Learning and Motivational Impact of Game-Based Learning: Comparing Face-to-Face and Online Formats on Computer Science Education
Creators: name: López-Fernández, Daniel
name: Gordillo, Aldo
name: Pérez, Jennifer
name: Tovar, Edmundo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: Contribution: This article analyzes the learning and motivational impact of teacher-authored educational video games on computer science education and compares its effectiveness in both face-to-face and online (remote) formats. This work presents comparative data and findings obtained from 217 students who played the game in a face-to-face format (control group) and 104 students who played the game in an online format (experimental group). Background: Serious video games have been proven effective at computer science education, however, it is still unknown whether the effectiveness of these games is the same regardless of their format, face-to-face or online. Moreover, the usage of games created through authoring tools has barely been explored. Research Questions: Are teacher-authored educational video games effective in terms of learning and motivation for computer science students? Does the effectiveness of teacher-authored educational video games depend on whether they are used in a face-to-face or online format? Methodology: A quasi-experiment has been conducted by using three instruments (pre-test, post-test, and questionnaire) with the purpose of comparing the effectiveness of game-based learning in face-to-face and online formats. A total of 321 computer science students played a teacher-authored educational video game aimed to learn about software design. Findings: The results reveal that teacher-authored educational video games are highly effective in terms of knowledge acquisition and motivation both in face-to-face and online formats. The results also show that some students' perceptions were more positive when a face-to-face format was used.
description: 10 pages, 3 figures. Accepted version of a journal article published in IEEE Transactions on Education
TRANSDISCIPLINARY APPROACH TO THE LEARNING PROCESS ORGANIZATION IN THE E-LEARNING INFORMATION ENVIRONMENT OF A COLLEGE
Creators: name: Elizaveta Afanasyevna Barakhsanova, Mikhail Semenovich Prokopyev
Publisher: name: TuEngr Group
Year: 2020
Subjects: Educational process organization
transdisciplinary approach
teacher, e-learning
e-learning information environment
Master's degree education.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 3, 11A03M: 1-12
Anion dependent structural diversity of cadmium(II) complexes: Synthesis, crystal structures, luminescence properties and unusual C-H/σ supramolecular interactions involving σ-aromatic M2X2 cores
Creators: name: Barman, Nikita
name: Saikat Banerjee
name: Brandão, Paula
name: Bauzá, Antonio
name: Frontera, Antonio
name: Saha, Amrita
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Marine Biology

description: Four complexes based on N,N’-bis(2-pyridylmethylene)-1,3-propanediamine (L) and different Cd(II) salts have been synthesized and characterized by single crystal X-ray diffraction analysis. The complexes are [Cd2(L)2(μ-Cl)2](ClO4)2 (1), [Cd2(L)2(μ-Br)2](ClO4)2 (2), [Cd(L)I](ClO4) (3) and [Cd(L)(NCS)2] (4). L exhibits the same coordination mode in 1-4. The radius of each anion plays a role in affecting the structures and luminescent intensities of the final products. CdCl2, CdBr2 and CdI2 react with L to produce chloride or bromido bridged binuclear complexes and mononuclear iodido complex, respectively, whereas an unusual mononuclear trigonal prismatic 4 is obtained when thiocyanate was used as a coligand. Photoluminescence properties of all the complexes show that the trend of fluorescence intensity is 1>4>2>3. All four complexes exhibit different supramolecular interactions such as C–H/σ, π–π and C–H/π and hydrogen bonding interactions. The experimental findings are complemented by density functional theory (DFT) calculations.
A short perspective on a posteriori error control and adaptive discretizations
Creators: name: Becker, Roland
name: Bordas, Stéphane P. A.
name: Chouly, Franz
name: Omnes, Pascal
Publisher: name: arXiv
Year: 2024
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: Error control by means of a posteriori error estimators or indica-tors and adaptive discretizations, such as adaptive mesh refinement, have emerged in the late seventies. Since then, numerous theoretical developments and improvements have been made, as well as the first attempts to introduce them into real-life industrial applications. The present introductory chapter provides an overview of the subject, highlights some of the achievements to date and discusses possible perspectives.
Febrifugine analogues as Leishmania donovani trypanothione reductase inhibitors: binding energy analysis assisted by molecular docking, ADMET and molecular dynamics simulation
Creators: name: Pandey, Rajan Kumar
name: Bajarang Vasant Kumbhar
name: Shubham Srivastava
name: Malik, Ruchi
name: Sundar, Shyam
name: Ambarish Kunwar
name: Prajapati, Vijay Kumar
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Visceral leishmaniasis affects people from 70 countries worldwide, mostly from Indian, African and south American continent. The increasing resistance to antimonial, miltefosine and frequent toxicity of amphotericin B drives an urgent need to develop an antileishmanial drug with excellent efficacy and safety profile. In this study we have docked series of febrifugine analogues (n = 8813) against trypanothione reductase in three sequential docking modes. Extra precision docking resulted into 108 ligands showing better docking score as compared to two reference ligand. Furthermore, 108 febrifugine analogues and reference inhibitor clomipramine were subjected to ADMET, QikProp and molecular mechanics, the generalized born model and solvent accessibility study to ensure the toxicity caused by compounds and binding-free energy, respectively. Two best ligands (FFG7 and FFG2) qualifying above screening parameters were further subjected to molecular dynamics simulation. Conducting these studies, here we confirmed that 6-chloro-3-[3-(3-hydroxy-2-piperidyl)-2-oxo-propyl]-7-(4-pyridyl) quinazolin-4-one can be potential drug candidate to fight against Leishmania donovani parasites.
Characterization, functional validation and gene expression patterns of two 14-3-3 isoforms from Vitis vinifera
Creators: name: Farace, G.
name: Visconti, S.
name: Marchive, C.
name: Aducci, P.
name: Marra, M.
name: Trossat-Magnin, C.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: In eukaryotic cells, 14-3-3 proteins constitute a family of conserved regulatory proteins which bind to a large number of phosphorylated partners. Although a great body of evidences accumulated in herbaceous species indicates that 14-3-3s play key roles in regulation of plant growth, information about function in tree plants is still very scarce. In this paper, we report the characterization of two novel 14-3-3s from grapevine (Vitis vinifera 'Cabernet Sauvignon') named VV1_CS and VV2_CS. The VV1_CS and VV2_CS cDNA were expressed in Escherichia coli and the recombinant proteins were shown to be functional proteins using plasma membrane H+-ATPase as target. Transcript analysis during grape development or under elicitor-induced stress revealed differential expression of the two 14-3-3 isoforms.
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
HSTPROMO Internal Proper Motion Kinematics of Dwarf Spheroidal Galaxies: I. Velocity Anisotropy and Dark Matter Cusp Slope of Draco
Creators: name: Vitral, Eduardo
name: van der Marel, Roeland P.
name: Sohn, Sangmo Tony
name: Libralato, Mattia
name: del Pino, Andrés
name: Watkins, Laura L.
name: Bellini, Andrea
name: Walker, Matthew G.
name: Besla, Gurtina
name: Pawlowski, Marcel S.
name: Mamon, Gary A.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We analyze four epochs of HST imaging over 18 years for the Draco dwarf spheroidal galaxy. We measure precise proper motions (PMs) for hundreds of stars and combine these with existing line-of-sight (LOS) velocities. This provides the first radially-resolved 3D velocity dispersion profiles for any dwarf galaxy. These constrain the intrinsic velocity anisotropy and resolve the mass-anisotropy degeneracy. We solve the Jeans equations in oblate axisymmetric geometry to infer the mass profile. We find the velocity dispersion to be radially anisotropic along the symmetry axis and tangentially anisotropic in the equatorial plane, with a globally-averaged value $\overline{β_{\mathrm B}}=-0.20^{+ 0.28}_{- 0.53}$, (where $1 - β_{\mathrm B} \equiv \langle v_{\mathrm{ tan}}^2 \rangle / \langle v_{\mathrm{ rad}}^2 \rangle$ in 3D). The logarithmic dark matter (DM) density slope over the observed radial range, $Γ_{\mathrm{ dark}}$, is $-0.83^{+ 0.32}_{- 0.37}$, consistent with the inner cusp predicted in $Λ$CDM cosmology. As expected given Draco's low mass and ancient star formation history, it does not appear to have been dissolved by baryonic processes. We rule out cores larger than 487, 717, 942 pc at respective 1-, 2-, 3-$σ$ confidence, thus imposing important constraints on the self-interacting DM cross-section. Spherical models yield biased estimates for both the velocity anisotropy and the inferred slope. The circular velocity at our outermost data point (900 pc) is $24.19^{+ 6.31}_{- 2.97} \ \mathrm{km~s^{-1}}s$. We infer a dynamical distance of $75.37^{+ 4.73}_{- 4.00}$ kpc, and show that Draco has a modest LOS rotation, with $\left = 0.22 \pm 0.09$. Our results provide a new stringent test of the so-called `cusp-core' problem that can be readily extended to other dwarfs.
description: 35 pages, 18 figures, 3 Tables. Accepted for publication in ApJ. Journal version has better readability. Data is available at Zenodo: https://zenodo.org/records/11111113
Challenges in modeling the dark matter halo of NGC 1052-DF2: Cored versus cuspy halo models
Creators: name: Aditya, K.
Publisher: name: arXiv
Year: 2024
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: The discovery of NGC 1052-DF2 and subsequent modeling have shown that NGC 1052-DF2 is deficient in dark matter and is in conflict with the standard stellar-to-halo mass ratio. In this work, we aim to resolve the degeneracy between the dynamical models on the mass estimate of the NGC 1052-DF2.We constructed mass models of NGC 1052-DF2 using an anisotropic distribution function with a radially varying anisotropy parameter and studied the effect of the various model parameters on the dark matter estimates. We used the observed stellar photometry as an input parameter to construct the distribution function and employed a Markov Chain Monte Carlo (MCMC) method to estimate the dark matter model parameters.We find that mass models with a cuspy dark matter halo have comparable $χ^{2}$ to models with zero dark matter. Moreover, the cuspy dark matter halo fails to consistently account for the observed velocity dispersion in the inner and outer regions of the galaxy. Consequently, we rule out the possibility of a cuspy dark matter halo for describing the mass models of NGC 1052 - DF2. Our study shows that the cored dark matter halo model with a total mass of $\log(M_{DM}/M_{\odot})=10.5$ explains the observed kinematics but requires an extraordinarily large scale length (20kpc) and an outer cutoff radius (26kpc). While the cored mass model provides a comparatively better fit, our findings emphasize that the mass models are largely unconstrained by the available kinematic data. Our results suggest that NGC 1052 - DF2 may not only have an ultra-diffuse stellar distribution but that it can, within uncertainties in the available kinematic data, potentially host an ultra-diffuse dark matter distribution compatible with the standard stellar-to-halo mass relation (SHMR) predicted by galaxy formation and evolution models
description: Accepted for publication in A&A
Modulation of gene expression in ex vitro grapevine (Vitis vinifera L.) by hormonal, oxidant and anti-oxidant stimuli
Creators: name: Carvalho, L. C.
name: Vilela, B. J.
name: Amáncio, S.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: When in vitro plantlets developed under low light conditions are exposed to high light upon transfer to ex vitro, it is common to observe symptoms of oxidative stress. In order to unravel more of what takes place in this phase of transition, paramount for plant survival, the present study focused on the expression of genes coding for proteins related with the metabolic pathways most affected upon transfer to ex vitro and monitored their expression in response to hormones and chemicals inducing alternative sinks for photosynthetic electron transport (PET) and reactive oxygen species (ROS) production. The expression of eight genes was significantly downregulated after all the treatments: catalase, beta-glucosidase, cytochrome P450, vegetative storage protein 2, wak1, a calcium binding protein, a meprin and TRAF homology domain-containing protein and a serine/threonine kinase. It was possible to verify that abscisic acid (ABA) was able to revert light induced gene expression and that the PET inhibitors DCMU and DPI had the same effect as ABA. ABA and jasmonic acid showed parallel effects, as both induced the expression of the same set of genes. Finally, exogenous cytokinin, instead of enhancing the plant´s response to high light led to the downregulation of light-responsive genes.
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
Efficiency of Single Nucleotide Polymorphisms to improve a genetic map of complex pedigree grapevines
Creators: name: Zyprian, E.
name: Simon, S.
name: Schwander, F.
name: Töpfer, R.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: A set of 47 SNP (single nucleotide polymorphisms) markers (Cabezas et al. 2011) was tested for their usefulness to improve a genetic map from the cross of GF.GA‑52-42 x 'Solaris' previously established with SSR markers (Schwander et al. 2012). 55.3 % of the SNPs showed informative segregation and 26 SNP markers were localized on 16 of the 19 linkage groups of grapevine. Five chromosome regions with large gaps of recombining SSR markers could be equipped by positioning a SNP marker there. One SNP marker, VV10992, was found linked to the major resistance locus Rpv10 and should be applicable for marker-assisted selection.
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
Influence of brassinosteroids on fruit yield and quality of table grape 'Alphonse Lavallée'
Creators: name: Isci, B.
name: Gökbayrak, Z.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: This research was carried out to determine the effects of a brassinosteroid compound (22S-, 23S-homobrassinolide) on yield and quality attributes of a field-grown table grape cultivar 'Alphonse Lavallée'. The vines were sprayed at anthesis (first week of May) with the compound over two growing seasons. The solutions were prepared at the concentrations of control, 10-3 and 10-4 mg∙L-1. Clusters were harvested when those of the control vines reached 16 °Brix. Yield and quality parameters were analyzed. There were no clear effects of the compound on yield and quality, except for the cluster length. The low concentration resulted in longer clusters. High concentration increased the tensile strength of the pedicel to some degree. Seasonal differences were observed in most of the parameters studied.
description: VITIS - Journal of Grapevine Research, Vol. 54 No. 1 (2015): Vitis
Multi-task Prompt Words Learning for Social Media Content Generation
Creators: name: Xue, Haochen
name: Zhang, Chong
name: Liu, Chengzhi
name: Wu, Fangyu
name: Jin, Xiaobo
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: Multimedia (cs.MM)
subject: FOS: Computer and information sciences

description: The rapid development of the Internet has profoundly changed human life. Humans are increasingly expressing themselves and interacting with others on social media platforms. However, although artificial intelligence technology has been widely used in many aspects of life, its application in social media content creation is still blank. To solve this problem, we propose a new prompt word generation framework based on multi-modal information fusion, which combines multiple tasks including topic classification, sentiment analysis, scene recognition and keyword extraction to generate more comprehensive prompt words. Subsequently, we use a template containing a set of prompt words to guide ChatGPT to generate high-quality tweets. Furthermore, in the absence of effective and objective evaluation criteria in the field of content generation, we use the ChatGPT tool to evaluate the results generated by the algorithm, making large-scale evaluation of content generation algorithms possible. Evaluation results on extensive content generation demonstrate that our cue word generation framework generates higher quality content compared to manual methods and other cueing techniques, while topic classification, sentiment analysis, and scene recognition significantly enhance content clarity and its consistency with the image.
description: 8 pages, 5 figures