cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Εναρμονίζοντας τον χώρο με την ανάγκη: Σχεδιασμός κέντρου υποστήριξης γυναικών στην Χαλέπα Χανίων
title: Harmonizing space with need: Designing a women’s support center in Chalepa, Chania
Creators: name: Χατζηνικολη Θεκλα
Publisher: name: Technical University of Crete
Year: 2023

description: Η παρούσα διπλωματική εργασία έχει ως στόχο τη δημιουργία ενός κέντρου υποστήριξης και ανάκαμψης γυναικών στην περιοχή της Χαλέπας Χανίων. Συγκεκριμένα, η επέμβαση γίνεται στην πλατεία του δημοτικού γηροκομείου, όπου αναπτύσσεται ένας χώρος υποστήριξης για τις γυναίκες που έχουν υποστεί κακοποίηση. Προτείνεται η αποκατάσταση του ερειπωμένου κτηρίου που βρίσκεται στην πλατεία και η αξιοποίηση αυτού για να στεγάσει ένα σημαντικό μέρος των αναγκών που δημιουργεί το φαινόμενο της κακοποίησης. Το αποκατεστημένο κτήριο θα λειτουργεί ως χώρος υποδοχής και εντός αυτού, μπορούν να πραγματοποιηθούν ομαδικές συνεδρίες ψυχοθεραπείας. Ακόμη, στο πλαίσιο ενός φιλόξενου και ασφαλούς περιβάλλοντος, προτείνεται η ανέγερση μικρών κτηρίων αγοράς κατά άξονα του παλιού κτηρίου, προκειμένου να προωθηθεί η κοινωνική ένταξη και η αυτονομία των γυναικών. Ένα κτήριο φιλοξενίας τοποθετείται βορειοδυτικά της πλατείας, δίπλα στο γηροκομείο, προσφέροντας χώρους διαμονής αλλά και χώρους διεξαγωγής εκπαιδευτικών προγραμμάτων, με σκοπό την ενδυνάμωση και την εκπαίδευση των γυναικών, προσφέροντας έτσι, ένα περιβάλλον που ενθαρρύνει την ανάπτυξη και την επιμόρφωση τους.
description: The present thesis aims to create a support and recovery center for women in the area of Chalepa in Chania, Crete. Specifically, the intervention takes place in the square of the municipal nursing home, where a support space for women who have suffered abuse will be developed. The proposal includes the restoration of the dilapidated building in the square and its utilization to accommodate a significant portion of the needs that arise from the phenomenon of abuse. The restored building will serve as a reception area, where group psychotherapy sessions can also be held. Furthermore, within a welcoming and secure environment, the construction of small market buildings along the axis of the old building is proposed to promote the social integration and autonomy of women. A hosting building is positioned to the northwest of the square, next to the nursing home, offering accommodation spaces as well as venues for educational programs. The goal is to empower and educate women, providing an environment that encourages their growth and development.
Additional file 1 of Serious neonatal morbidities are associated with differences in DNA methylation among very preterm infants
Creators: name: Everson, Todd M.
name: T. Michael O’Shea
name: Burt, Amber
name: Hermetz, Karen
name: Carter, Brian S.
name: Helderman, Jennifer
name: Hofheimer, Julie A.
name: McGowan, Elisabeth C.
name: Neal, Charles R.
name: Pastyrnak, Steven L.
name: Smith, Lynne M.
name: Soliman, Antoine
name: DellaGrotta, Sheri A.
name: Dansereau, Lynne M.
name: Padbury, James F.
name: Lester, Barry M.
name: Marsit, Carmen J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Biotechnology
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Additional file 1: Supplemental Figures S1–S8.
Sticky stuff: biological cohesion for scour and erosion prevention
Creators: name: Schindler, Rob
name: Whitehouse, Richard
name: Harris, John
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Mental Health
subject: Computational Biology

description: This study examines the potential for biological cohesion to arrest scour erosion at marine infrastructure. Biological cohesion occurs naturally in sedimentary environments, and is caused by extracellular polymeric substances (EPS) which result from the life cycles of microorganisms. EPS is known to dramatically increase the resistance of natural biomediated sediment to erosive hydrodynamic forces. In this study, we test, for the first time, whether EPS can be deliberately added to a sediment to mitigate against scour erosion – a process we term ‘biostabilisation’. A systematic laboratory experiment is used to investigate the effects of an EPS additive on scour erosion around a monopile in a sand substrate. Results show that increasing EPS content causes a progressive reduction in equilibrium scour depth, the volume of excavated material and the timescale required to reach equilibrium scour morphology. These parameters are linearly related to EPS content, showing that the effects of EPS on the physical processes required for erosion to occur are concentration dependent. It can be concluded that biostabilisation offers a potential new ecologically engineered, nature-based solution to a range of scour and erosion scenarios. The economic and environmental advantages are discussed, and a methodology for biostabilisation use in individual erosion mitigation scenarios is proposed.
Additional file 1 of Long-term clinical course and outcomes of immunoglobulin G4-related lung disease
Creators: name: Jieun Kang
name: Shinhee Park
name: Chae, Eun Jin
name: Song, Joon Seon
name: Hwang, Hee Sang
name: Kim, Sun Jong
name: Song, Tae Jun
name: Myung-Whan Kim
name: Song, Jin Woo
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Table S1. Comparison of baseline characteristics of patients with IgG4-RLD according to the radiologic subtypes. Table S2. Histopathologic findings according to the radiologic subtype. Table S3. Comparison of treatment in patients with IgG4-RLD according to the radiologic subtypes. Table S4. Differential cell counts of bronchoalveolar lavage fluid.
Intramolecular and intermolecular Schmidt reactions of alkyl azides with aldehydes
Creators: name: Lee, H.-L.
name: Aubé, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: Despite recent advances in the use of alkyl azides in ring expansion reactions of ketones, there has been little work done on the corresponding chemistry of aldehydes. In the present study, the Lewis acid-promoted reactions of alkyl azides with aldehydes were studied in both intermolecular and intramolecular contexts. The intramolecular reactions of azidoalkyl aldehydes in which the azide and carbonyl groups were separated by 2-5 carbons were examined. Although the examples having the shortest tether failed (3-azidopropanals), each of the other systems gave good yields of either NH-substituted lactams (resulting from hydride migration in the initially formed azidohydrin adduct) or formamides (alkyl migration). The product formed was dependent on the chain length of the starting azido aldehyde. The intermolecular reactions were less efficient, requiring TiCl4 promotion for even moderate yields, and in each case gave mixtures of products resulting from hydride and alkyl migration.
Moduli of vector bundles on higher-dimensional base manifolds - Construction and Variation
Creators: name: Greb, Daniel
name: Ross, Julius
name: Toma, Matei
Publisher: name: arXiv
Year: 2015
Subjects: subject: Algebraic Geometry (math.AG)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We survey recent progress in the study of moduli of vector bundles on higher-dimensional base manifolds. In particular, we discuss an algebro-geometric construction of an analogue for the Donaldson-Uhlenbeck compactification and explain how to use moduli spaces of quiver representations to show that Gieseker-Maruyama moduli spaces with respect to two different chosen polarisations are related via Thaddeus-flips through other "multi-Gieseker"-moduli spaces of sheaves. Moreover, as a new result, we show the existence of a natural morphism from a multi-Gieseker moduli space to the corresponding Donaldson-Uhlenbeck moduli space.
description: 21 pages; v2: minor changes as requested by referee, added Remark 4.7 concerning Compactified Jacobians; to appear in the proceedings of VBAC 2014 "Algebraic Varieties: Bundles, Topology, Physics"
The concentrated polyaluminum chloride with tailor-made distribution of al species: synthesis, distribution and transformation of al species, and coagulation performance
Creators: name: Panahi, Reza
name: Ravi, Mehdi
name: Abdollahi, Kourosh
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Production of concentrated polyaluminum chloride (PACl) with the proper distribution of Al species (Ala, Alb, and Alc) is still a challenging issue on both industrial and laboratory scale. Hence, the effects of total aluminum concentration (AlT) at high levels, regular basicity values, and low base injection rates on the distribution of Al species in PACl solutions were investigated using quadratic models. The results confirmed the possibility to synthesize tailor-made PACl solutions with a specified value of either Ala, Alb, or Alc within the range of 22–51%, 4–51%, or 0.5–74%, respectively. For instance, in agreement with the predicted value, a PACl sample rich in both Alb (42,200 ppm) and AlT was produced by applying the basicity of 1.7, AlT of 9.07% as Al2O3, and basification rate of 0.48 ml/h. In addition, the maximum Alc could be acquired by exploiting the highest C, B, and Q values. This condition also minimized both Ala and Alb. The trends of Ala and Alc changes by the increment of basicity were concave and convex, respectively, while Alb showed either a decreasing trend or a concave pattern based on the values of injection rate and AlT. The Alb-rich PACl sample was effectively applied for turbidity removal from synthetic wastewater at various pHs and initial turbidities. At best, residual turbidity of about 1% was observed after the coagulation process. These findings can be constructive for the production and application of tailor-made PACl.
(502360) Maria W. Rogers
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Cation-π control of regiochemistry of intramolecular Schmidt reactions en route to bridged bicyclic lactams
Creators: name: Aubé, J.
name: Yao, L.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2007

description: The regiochemistry of the intramolecular Schmidt reaction of 2-substituted ketones has proved susceptible to control by the placement of an aromatic group at an adjacent position, permitting the selective formation of a series of bridged bicyclic lactams from these substrates. This phenomenon is ascribed to the presence of stabilizing through-space interactions between the positively charged leaving group and the aromatic substituents in a key azidohydrin intermediate.
(502352) Ellen [Masters]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 1 of Siblings’ life aspirations in the context of Duchenne muscular dystrophy: a mixed-methods case-control study
Creators: name: Schwartz, Carolyn E.
name: Biletch, Elijah
name: Stuart, Richard B. B.
name: Rapkin, Bruce D.
Publisher: name: figshare
Year: 2022
Subjects: subject: Cell Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy

description: Additional file 1: Supplemental Table 1. List of Measures by Age Cohort.
Sticky Stuff: Biological Cohesion for Scour and Erosion Prevention
Creators: name: Schindler, Rob
name: Whitehouse, Richard
name: Harris, John
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Cell Biology
subject: Biotechnology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Mental Health
subject: Computational Biology

description: This study examines the potential for biological cohesion to arrest scour erosion at marine infrastructure. Biological cohesion occurs naturally in sedimentary environments, and is caused by extracellular polymeric substances (EPS) which result from the life cycles of microorganisms. EPS is known to dramatically increase the resistance of natural biomediated sediment to erosive hydrodynamic forces. In this study we test, for the first time, whether EPS can be deliberately added to a sediment to mitigate against scour erosion – a process we term ‘biostabilisation’. A systematic laboratory experiment is used to investigate the effects of an EPS additive on scour erosion around a monopile in a sand substrate. Results show that increasing EPS content causes a progressive reduction in equilibrium scour depth, the volume of excavated material and the timescale required to reach equilibrium scour morphology. These parameters are linearly related to EPS content, showing that the effects of EPS on the physical processes required for erosion to occur are concentration dependent. It can be concluded that biostabilisation offers a potential new ecologically engineered, nature-based solution to a range of scour and erosion scenarios. The economic and environmental advantages are discussed, and a methodology for biostabilisation use in individual erosion mitigation scenarios is proposed.
Distribution of Chern number by Landau level broadening in Hofstadter's butterfly
Creators: name: Yoshioka, Nobuyuki
name: Matsuura, Hiroyasu
name: Ogata, Masao
Publisher: name: arXiv
Year: 2015
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: We discuss the relationship between the quantum Hall conductance and a fractal energy band structure, Hofstadter's butterfly, on a square lattice under a magnetic field. At first, we calculate the Hall conductance of Hofstadter's butterfly on the basis of the linear responce theory. By classifying the bands into some groups with a help of continued fraction expansion, we find that the conductance at the band gaps between the groups accord with the denominators of fractions obtained by aborting the expansion halfway. The broadening of Landau levels is given as an account of this correspondance.
description: 7 pages, 5 figures. To be published in J. Phys. Conf. Series
Municipal solid waste generation and its compositional assessment for efficient and sustainable infrastructure planning in an intermediate city of Pakistan
Creators: name: Nadeem, K.
name: Shahzad, S.
name: Hassan, A.
name: Younus, M. Usman
name: Gillani, S. Asad Ali
name: Farhan, K.
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Science Policy
subject: Mental Health
subject: Virology

description: It is imperative to design and operate sustainable solid waste management (SWM) systems in cities based on the results of waste amount and characterization study (WACS). In this work, WACS was conducted, and results were used to design an SWM system for an intermediate city of Pakistan. The study revealed that about 110 tons of solid waste per day is generated with a per capita rate of 0.337 kg/day. Around 51.2 % of mixed municipal solid waste (MSW) is organic in nature, and its non-scientific disposal is resulting in higher greenhouse gas (GHG) emissions. It was also found that more than 80 % of valuables are taken away by the informal sector during the transfer of MSW from the generation source to the dumping site. Ultimate analyses showed that the moisture content (MC) and carbon to nitrogen (C:N) ratio were 64.23 % and 51.14 %, respectively. Proximate analysis revealed that moisture and calorific value were 57 % and 3505 BTU/lb., respectively. Based on these results, a material sorting facility (MSF) was proposed, with an estimated investment cost of US $3.64 million. However, efficiency of the existing collection system is limited to 32 % only. In order to improve the collection efficiency (>90 %), an additional investment of US $1.638 million was estimated with an operations and maintenance (O&M) cost of US $19.25 per ton. Existing non-scientific MSW disposal practices contribute 32079.61 CO2e tons/year of GHG emissions. The proposed MSF followed by composting is estimated to reduce GHG emissions by 38 % to 19722.38 CO2e tons/year.
Quantized recurrence time in iterated open quantum dynamics
Creators: name: Sinkovicz, P.
name: Kurucz, Z.
name: Kiss, T.
name: Asbóth, J. K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The expected return time to the original state is a key concept characterizing systems obeying both classical or quantum dynamics. We consider iterated open quantum dynamical systems in finite dimensional Hilbert spaces, a broad class of systems that includes classical Markov chains and unitary discrete time quantum walks on networks. Starting from a pure state, the time evolution is induced by repeated applications of a general quantum channel, in each timestep followed by a measurement to detect whether the system has returned to the original state. We prove that if the superoperator is unital in the relevant Hilbert space (the part of the Hilbert space explored by the system), then the expectation value of the return time is an integer, equal to the dimension of this relevant Hilbert space. We illustrate our results on partially coherent quantum walks on finite graphs. Our work connects the previously known quantization of the expected return time for bistochastic Markov chains and for unitary quantum walks, and shows that these are special cases of a more general statement. The expected return time is thus a quantitative measure of the size of the part of the Hilbert space available to the system when the dynamics is started from a certain state.
Additional file 1 of A comparison of the effects and usability of two exoskeletal robots with and without robotic actuation for upper extremity rehabilitation among patients with stroke: a single-blinded randomised controlled pilot study
Creators: name: Park, Jin Ho
name: Gyulee Park
name: Kim, Ha Yeon
name: Ji-Yeong Lee
name: Yeajin Ham
name: Donghwan Hwang
name: Suncheol Kwon
name: Shin, Joon-Ho
Publisher: name: figshare
Year: 2020
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences

description: Additional file 1: Table S1. Comparison of the kinematic outcomes between the ACT and PSV groups at T0, T1, and T2.
Remote control of diastereoselectivity in intramolecular reactions of chiral allylsilanes
Creators: name: Aube, J.
name: Ban, S.
name: Judd, W.R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: During investigations of cyclization reactions between chiral allylsilanes and N-acyliminium ions, it was discovered that a suitably positioned benzyloxy group on the allylsilane component caused a reversal in the diastereoselectivity of these reactions relative to that normally observed with alkyl-substituted allylsilanes. This effect was subsequently observed in two other reaction types. Investigations into this effect led to the proposal of product formation through thermodynamic control facilitated by neighboring group interactions with a transient cationic species. This hypothesis was experimentally supported by the isolation of an intermediate in the proposed mechanistic pathway.
Additional file 1 of Power spectral analysis of heart rate variability is useful as a screening tool for detecting sympathetic and parasympathetic nervous dysfunctions in Parkinson’s disease
Creators: name: Miyagi, Tomo
name: Yamazato, Masanobu
name: Nakamura, Takuto
name: Tokashiki, Takashi
name: Namihira, Yukihiro
name: Kokuba, Kazuhito
name: Ishihara, Satoshi
name: Sakima, Hirokuni
name: Ohya, Yusuke
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Supplementary Figure 1. Blood pressure, heart rate, and values of LF and HF powers during head-up tilt test of representative control subject (A) and Parkinson’s disease with orthostatic hypotension (B). Supplementary Table 1. Characteristics and the results of autonomic function tests in healthy control subjects and patients with Parkinson’s disease (PD) by gender. Supplementary Figure 2. Correlations between resting LF power and heart-to-mediastinum (H/M) ratio of 123I-meta-iodobenzylguamidine (MIBG) uptake (A) and correlations between resting HF power and coefficient variation of RR intervals (CVRR) (B) in male patients with PD. Supplementary Figure 3. Correlations between resting LF power and heart-to-mediastinum (H/M) ratio of 123I-meta-iodobenzylguamidine (MIBG) uptake (A) and correlations between resting HF power and coefficient variation of RR intervals (CVRR) (B) in female patients with PD. Supplement Figure 4. The correlation between resting LF power and HF power in the patients with PD by gender (A. Men, B. Women).
Additional file 3 of Configurations for obtaining in-consultation assistance from supervisors in general practice training, and patient-related barriers to trainee help-seeking: a survey study
Creators: name: Sturman, Nancy J.
name: Tapley, Amanda
name: Driel, Mieke L. Van
name: Holliday, Elizabeth G.
name: Ball, Jean I.
name: Davey, Andrew R.
name: Fielding, Alison
name: FitzGerald, Kristen
name: Spike, Neil A.
name: Magin, Parker J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Marine Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 3. Full questionnaires used for the data collection period relevant to the current analysis.
Cheating is evolutionarily assimilated with cooperation in the continuous snowdrift game
Creators: name: Sasaki, Tatsuya
name: Okada, Isamu
Publisher: name: arXiv
Year: 2015
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Adaptation and Self-Organizing Systems (nlin.AO)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: It is well known that in contrast to the Prisoner's Dilemma, the snowdrift game can lead to a stable coexistence of cooperators and cheaters. Recent theoretical evidence on the snowdrift game suggests that gradual evolution for individuals choosing to contribute in continuous degrees can result in the social diversification to a 100% contribution and 0% contribution through so-called evolutionary branching. Until now, however, game-theoretical studies have shed little light on the evolutionary dynamics and consequences of the loss of diversity in strategy. Here we analyze continuous snowdrift games with quadratic payoff functions in dimorphic populations. Subsequently, conditions are clarified under which gradual evolution can lead a population consisting of those with 100% contribution and those with 0% contribution to merge into one species with an intermediate contribution level. The key finding is that the continuous snowdrift game is more likely to lead to assimilation of different cooperation levels rather than maintenance of diversity. Importantly, this implies that allowing the gradual evolution of cooperative behavior can facilitate social inequity aversion in joint ventures that otherwise could cause conflicts that are based on commonly accepted notions of fairness.
description: 30 pages, 3 tables, 5 figures
Additional file 10 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 10 Transposon-like sequences in PRF1 loci of Danio rerio and Oryzias latipes. PRF1 genes are depicted to scale with intron/exon boundaries (blue boxes). Pseudogenes are depicted in pink. Transposon-like sequences are shown as black boxes.
Additional file 1 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 1 Genome assemblies and automatic annotations used in this work
Additional file 2 of A bloody interaction: plasma proteomics reveals gilthead sea bream (Sparus aurata) impairment caused by Sparicotyle chrysophrii
Creators: name: Riera-Ferrer, Enrique
name: Piazzon, M. Carla
name: Del Pozo, Raquel
name: Palenzuela, Oswaldo
name: Estensoro, Itziar
name: Sitjà-Bobadilla, Ariadna
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 2: Figure S2. Partial least-squares discriminant analysis model overview depicting the optimal number of components used to build the model (p1-p5). The Y-axis represents the cumulative fit (R2Y) and prediction (Q2Y) coefficients for each of the components (A). Validation of the model (permutation test, 500 permutations) to estimate R2Y and Q2Y significance. pR2Y and pQ2 are considered significant at P < 0.05 (B). Observation diagnostics was performed to detect outliers by plotting the score and orthogonal distances of each sample (red = control fish; blue = fish with low/medium infection degree; green = fish with high infection degree). No outliers were detected in this model (C).
(502353) Emma Ashfordby Trenchard
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 1 of Configurations for obtaining in-consultation assistance from supervisors in general practice training, and patient-related barriers to trainee help-seeking: a survey study
Creators: name: Sturman, Nancy J.
name: Tapley, Amanda
name: Driel, Mieke L. Van
name: Holliday, Elizabeth G.
name: Ball, Jean I.
name: Davey, Andrew R.
name: Fielding, Alison
name: FitzGerald, Kristen
name: Spike, Neil A.
name: Magin, Parker J.
Publisher: name: figshare
Year: 2020
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Biotechnology
subject: Marine Biology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. Survey items specifically concerning in-consultation help-seeking.
(502354) Ellen Bowden
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Cyclization of a carbon-centered radical derived from oxaziridine cleavage
Creators: name: Usuki, Y.
name: Peng, X.
name: Aubé, J.
name: Manyem, S.
name: Gülgeze, B.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Treatment of an oxaziridine with low-valent iron or copper salts generates a carbon-centered radical able to cyclize onto an appended olefin.
Probing protein orientation near charged nanosurfaces for simulation-assisted biosensor design
Creators: name: Cooper, Christopher D.
name: Clementi, Natalia C.
name: Barba, Lorena A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Chemical Physics (physics.chem-ph)
subject: FOS: Physical sciences

description: Protein-surface interactions are ubiquitous in biological processes and bioengineering, yet are not fully understood. In biosensors, a key factor determining the sensitivity and thus the performance of the device is the orientation of the ligand molecules on the bioactive device surface. Adsorption studies thus seek to determine how orientation can be influenced by surface preparation. In this work, protein orientation near charged nanosurfaces is obtained under electrostatic effects using the Poisson-Boltzmann equation, in an implicit-solvent model. Sampling the free energy for protein GB1D4' at a range of tilt and rotation angles with respect to the charged surface, we calculated the probability of the protein orientations and observed a dipolar behavior. This result is consistent with published experimental studies and combined Monte Carlo and molecular dynamics simulations using this small protein, validating our method. More relevant to biosensor technology, antibodies such as immunoglobulin G are still a formidable challenge to molecular simulation, due to their large size. We obtained the probability distribution of orientations for the iso-type IgG2a at varying surface charge and salt concentration. This iso-type was not found to have a preferred orientation in previous studies, unlike the iso-type IgG1 whose larger dipole moment was assumed to make it easier to control. We find that the preferred orientation of IgG2a can be favorable for biosensing with positive surface charge of 0.05C/m$^{2}$ or higher and 37mM salt concentration. The results also show that local interactions dominate over dipole moment for this protein. Improving immunoassay sensitivity may thus be assisted by numerical studies using our method (and open-source code), guiding changes to fabrication protocols or protein engineering of ligand molecules to obtain more favorable orientations.
description: 14 pages, 10 figures -- This version is revised post peer review, and supersedes all previous ones. Note that v3 was reduced considerably from the previous ones, due to the material being split in two papers. Another preprint was submitted (arXiv:1506.03745) with the material that was cut of this paper, corresponding to how the papers were submitted to peer-reviewed journals
A combined intramolecular Diels-Alder/intramolecular Schmidt reaction: Formal synthesis of (±)-stenine
Creators: name: Golden, J.E.
name: Aubé, J.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2002

description: Four stereocenters and three rings are established in one step in a new formal synthesis of (±)-stenine (see scheme). This key reaction cascade consists of an intramolecular Diels-Alder reaction followed by an intramolecular Schmidt reaction. The resulting tricyclic intermediate was readily transformed into a known intermediate en route to stenine, thus completing the formal synthesis.
Additional file 4 of A bloody interaction: plasma proteomics reveals gilthead sea bream (Sparus aurata) impairment caused by Sparicotyle chrysophrii
Creators: name: Riera-Ferrer, Enrique
name: Piazzon, M. Carla
name: Del Pozo, Raquel
name: Palenzuela, Oswaldo
name: Estensoro, Itziar
name: Sitjà-Bobadilla, Ariadna
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified

description: Additional file 4: Figure S4. Plasma biotin values measured in control (C, n = 50) and Sparicotyle chrysophrii-infected fish with a medium/low (M/L, n = 31) and high (H, n = 16) infection degree (A). Normalised protein abundance values of biotinidase (B) measured by proteomics in plasma samples of control (C, n = 5), medium/low (M/L, n = 10), and high (H, n = 5) infection groups. Values are represented as mean ± SEM and statistical differences among groups are noted with different letters (Kruskall-Wallis test, P < 0.05).
(502357) Catherine Cooper
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(502349) John Newnham Winter
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 8 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 8 Phylogenetic relationships between mammalian PRF1 genes. Bayesian inference (left) and maximum-parsimony (right) phylogenetic trees from mammalian perforin-1 sequences. Names in red belong to genes in loci different from ADAMTS14-PALD1. Oan, Ornithorhynchus anatinus; Pci, Phascolarctos cinereus; Mmu, Mus musculus; Hgl, Heterocephalus glaber; Dno, Dasypus novemcinctus; Laf, Loxodonta africana; Pca, Procavia capensis; Eeu, Erinaceus europaeus; Hsa, Homo sapiens; Cch, Condylura cristata; Nsc, Neomonachus schauinslandi; Eca, Equus caballus; Ssc, Sus scrofa; Bta, Bos taurus; Pca, Physeter catodon; Bbo, Balaenoptera bonaerensis; Dle, Delphinapterus leucas; Oor, Orcinus orca; Cpl, Chiloscyllium plagiosum.
(502350) Herbert Vincent
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Additional file 9 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 9 Sequence read archive entries used to study bird PRF1 expression
Ecosystem Services & Landscape Connectivity in the Eno River and New Hope Creek-Jordan Lake Watersheds, NC
Creators: name: Maron, Julia
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Ecosystem services are the benefits that humans receive from nature such as drinking water, fuel, food, and fiber. Landscape connectivity is the degree that landscapes facilitate the movement of species and other materials. Landscape connectivity is important for biodiversity conservation and critical for sustaining populations of species across habitats. In 2019, the Eno-New Hope Landscape Conservation Group conducted a landscape corridor mapping analysis to identify habitat corridors in the Eno River and New Hope Creek-Jordan Lake watersheds, along with a review of local municipality planning documents to identify relevant conservation planning efforts. In this project, I used the resulting priority network created by the Eno-New Hope Landscape Conservation Group and raster layers for areas of unprotected forests performing ecosystem services to determine areas of overlap. Once identified, the results illustrated how natural and seminatural habitats are connected via habitat corridors. The results of this pilot analysis are useful for land use planners in understanding spatially where it is critical to keep development limited to reduce fragmentation across the landscape.
Additional file 11 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 11 SignalP prediction of secretion peptides in c2PRF1 products
Additional file 12 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 12 RNA-Seq reads aligned to Rhincodon typusPRF1. Top, Alignment of RNA-Seq reads from whale-shark blood cells to a genomic region belonging to PRF1 and showing premature stop codons. The genomic sequence is shown on a green background. RNA-Seq reads are depicted on a blue (high-quality base) or red (low-quality base) background. Dots and commas represent bases equal to those of the corresponding genomic location. Dashes represent deletions of the reads as compared to the genomic sequence. Bottom, translation of the genomic sequence (green background) and two of the RNA-Seq reads from the top panel.
(502347) Dacre Vincent
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Discussion on the paper: Hypotheses testing by convex optimization by Goldenshluger, Juditsky and Nemirovski
Creators: name: Dalalyan, Arnak S.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We briefly discuss some interesting questions related to the paper "Hypotheses testing by convex optimization" by Goldenshluger, Juditsky and Nemirovski.
description: To appear in the EJS
Additional file 13 of Frequent birth-and-death events throughout perforin-1 evolution
Creators: name: Araujo-Voces, Miguel
name: Quesada, Víctor
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences

description: Additional file 13 STX4-ZNF646 locus in turtles. PRF1 genes are depicted to scale with intron/exon boundaries (blue boxes). Pseudogenes are depicted in pink. Flanking genes may be cropped for ease of depiction.
"My experience doesn't matter to you?": A Community-Based Participatory Research (CBPR) Approach to Describe Experiences of Birthing People of Color and Community-Based Doula Support Strategies
Creators: name: Berry, Anne M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2022

description: Background
Black people in the United States have three to four times the risk of pregnancy-related death than do white people, and racial disparities in birth outcomes are worsening. There is increasing awareness of structural racism’s role in perpetuating these disparities, but still limited inquiry into the experiences of Black, Indigenous and People of Color (BIPOC) communities during pregnancy, birth and the postpartum period.
My study aims to understand how the needs of birthing people of color in Durham are being met and not met where they receive care. The study’s goal is to make their experiences known and guide health professionals and policymakers working for maternal health equity.

Methods

I used a CBPR approach to allow centering expertise of people from the communities experiencing maternal health disparities. Community members participated in planning, participant recruitment, designing interview guides, and data collection, analysis and interpretation. We conducted semi-structured interviews with board members and volunteer doulas from our partner organization, Mobilizing African American Mothers for Empowerment (MAAME). We also conducted a focus group with people of color who had given birth in the Durham area recently. The focus group and interviews occurred via video-conference, by participants’ preference, given COVID-19 risk.

Results

My collaborator and I conducted semi-structured interviews were conducted with three MAAME board members and two doulas, and a focus group with six individuals who had given birth in the past two years and identified as people of color. I developed a grounded theory based on coding of the interview and focus group transcripts, describing the variables contributing to having a good birth journey or, alternately, being denied a good birth, along with strategies employed by community-based doulas to mitigate harm and potentially help a birthing person redirect onto the pathway to a good birth journey. The central idea that emerged was that of a birthing person being treated as an individual, which included both being valued, related to time, and being known, a phenomenon identified in a recent qualitative study of the meaning of high-quality maternity care for people of color in Boston (Roder-DeWan et al., 2021).

Conclusions

This study demonstrates the relevance and effectiveness of a CBPR approach to maternal health equity. Instead of narrowing focus based on researchers’ hypotheses, we were able to hear and highlight priorities of birthing people of color themselves.

Public Health Implications

Reproductive justice researchers and advocates emphasize the inadequacy of maternal health equity interventions that originate outside the affected communities. A CBPR approach is necessary to identify and support community-based solutions.
(502348) Julia [Vincent]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
lncRNAs: potential therapeutic targets and biomarkers for pancreatic cancer?
Creators: name: Montes, Marta
name: Arnes, Luis
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: lncRNAs: potential therapeutic targets and biomarkers for pancreatic cancer?