cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Factors influencing hepatitis B vaccination intention and behavior among college students in Tibet: Insights from the expanded theory of planned behavior
Creators: name: Chen, Qi
name: Ma, Jun
name: Wu, Ruipeng
name: Wang, Yingting
name: Ma, Xiaoxin
name: Zheng, Xiaolei
name: Jin, Hui
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Sociology
subject: FOS: Sociology
subject: Science Policy

description: Hepatitis B (Hep B) remains a critical public health issue globally, particularly in Tibet, where vaccination rates and influencing factors among college students are yet understudied. This study applies a cross-sectional design to investigate the Hep B vaccination rate among 1,126 college students in Tibet and utilizes the expanded theory of planned behavior (ETPB) to identify vaccination behavior intention (BI) and vaccination behavior (VB). Stratified cluster sampling across three universities was used to assess behavioral attitudes (BA), subjective norms (SN), perceived behavioral control (PBC), past vaccination history (PVH) and vaccination knowledge (VK), and used structural equation modeling (SEM) for model validation and multi-group comparison. Results indicated that 16.3% of students had received the Hep B vaccine. VK notably improved BA toward vaccination (β = 0.518, p < .001). BA (β = 0.232, p < .001), PBC (β = 0.239, p < .001), SN (β = 0.385, p < .001) positively influenced BI. However, PVH failed to predict BI. BI (β = 0.448, p < .001) and PVH (β = 0.127, p < .001) were significant predictors of VB. Significant ethnic variations were noted. The positive effect of PVH on VB (β = 0.151, p < .001) and the mediating role of PBC in VB (β = 0.076, p < .05) were significant among Tibetan students. The effect of VK on BA was stronger among Tibetans (β = 0.503, p < .05),while the impact of attitude on BI was more pronounced among Han students (β = 0.366, p < .05). The vaccination rate for Hep B among college students in Tibet is relatively low, and the ETPB model effectively explains their vaccination intentions and behaviors. Tailored intervention strategies for Tibetan and Han students are recommended to boost vaccination rates effectively.
THE ROLE OF STEREOTYPE THREAT AND IMPOSTOR PHENOMENON IN PREDICTING FEMALE UNDERGRADUATE STUDENTS’ PERSISTENCE IN STEM
Creators: name: Wierzchowski, Kathy Ann
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mental health services
Counselling psychology
Health psychology

description: There is a lack of literature that has investigated the relationships between stereotype threat, impostor phenomenon, and other related constructs on career development, particularly for women in STEM. While various resources (National Science Foundation, 2013; Sax, Kanny, Jacobs, Whang, Weintraub, & Hroch, 2016; US Department of Labor, 2014) have highlighted the gender gap and “leaky pipeline” in STEM, it is important to further investigate and understand why these phenomena occur and continue to persist. In this study, I used a mixed methods approach which used a quantitative SEM analyses and qualitative interview to further examine the paths between chilly climate, impostor phenomenon, stereotype threat, science self-efficacy, fear of failure, fear of success, academic major satisfaction, and persistence in STEM in a sample of undergraduate females. Several hypotheses were formed in order to better understand the mediation effects of these variables upon one another. Stereotype threat was found to be endorsed at a lesser rate than anticipated, while impostor phenomenon was endorsed at a higher rate. Science self-efficacy was also found to play an important role in the predicted relationships among variables, relating to both academic major satisfaction and persistence. These quantitative results were supported by data gathered in qualitative interviews. Implications for research and practice around concerns of impostor phenomenon, stereotype threat, and fears of failure and success are discussed.
title: Development of anaerobic culturing methods to study the evolution and of the human intestinal microbiota
Creators: name: Browne, HP
Publisher: name: London School of Hygiene & Tropical Medicine
Year: 2018

description: The human gastrointestinal tract is colonised by a diverse range of health-associated bacteria, in addition to other microorganisms, termed the intestinal microbiota. Sequence-based, culture-independent approaches have revolutionised this field of study, however, due to the perception that these bacteria are largely unculturable, in vitro phenotypic analysis has been hindered. In this study, an anaerobic culturing workflow was developed which revealed that the majority of these bacteria can be cultured using one growth medium. In total, 137 characterised and novel bacterial species were isolated and whole-genome sequenced. Inter-host transmission of the intestinal microbiota may represent a means to maintain a diverse assortment of commensal bacteria within individuals, yet it remains a poorly understood process. Some anaerobic pathogens utilise resilient aero-tolerant spores to survive externally and to facilitate transmission to new hosts. To investigate if commensal spore-formers utilise similar mechanisms, a phenotypic screen was incorporated into the culturing workflow to target spore-forming bacteria. This resulted in the isolation of 66 phylogenetically diverse, spore-forming species which, through subsequent phenotypic characterisation are shown to be specialised for host-to-host transmission and intestinal colonisation. Further phylogenetic and evolutionary analysis revealed body-site associated, loss of sporulation has occurred in different taxa. Also, loss of sporulation is associated with features of host-adaptation that are not present in spore-formers such as a smaller genome size and loss of genetic redundancy. This suggests that the human intestinal microbiota is populated by commensal bacteria that have evolved to engage in opposing lifestyles, either orientated towards inter-host dispersal or within-host adaptation.
This study demonstrates the intestinal microbiota is not unculturable. In addition, commensal microbial transmission may be more prevalent than once thought as a significant proportion of these bacteria can survive outside of a host through the use of spores that are intrinsically resistant to environmental stresses.
sj-docx-3-car-10.1177_19476035211025817 – Supplemental material for Differential Contribution of the Medial and the Lateral Side of the Joint to Symptoms in Knee Osteoarthritis: A Radiographic and Laboratory Analysis in the Nagahama Study
Creators: name: Nigoro, Kazuya
name: Ito, Hiromu
name: Kawata, Tomotoshi
name: Ishie, Shinichiro
name: Morita, Yugo
name: Nishitani, Kohei
name: Aoyama, Tomoki
name: Tabara, Yasuharu
name: Matsuda, Fumihiko
name: Narumiya, Shu
name: Matsuda, Shuichi
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, sj-docx-3-car-10.1177_19476035211025817 for Differential Contribution of the Medial and the Lateral Side of the Joint to Symptoms in Knee Osteoarthritis: A Radiographic and Laboratory Analysis in the Nagahama Study by Kazuya Nigoro, Hiromu Ito, Tomotoshi Kawata, Shinichiro Ishie, Yugo Morita, Kohei Nishitani, Tomoki Aoyama, Yasuharu Tabara, Fumihiko Matsuda, Shu Narumiya and Shuichi Matsuda in CARTILAGE
Reconstructing Relationships of Desire: Homosexuality in Spanish Golden Age Theater
Creators: name: Paredes Ocampo, Eduardo
Publisher: name: Sociedad Menéndez Pelayo
Year: 2024
Subjects: subject: Actors
subject: Performances
subject: Queer theory
subject: Drama
subject: Gay men
subject: Spain
subject: Art
subject: Inquisition
subject: Vega, Lope de, 1562-1635
subject: Theater

description: The figure of the marión, maricón or puto—the male homosexual—appears in many Spanish Golden Age plays. The critical approaches to this dramatic type have centered on thematic and textual issues, ignoring the performative cues inscribed on the character. For this reason, this paper reconstructs the acting of male homoeroticism in the comedia, engaging with the comediante's paralinguistic features and bodily gestures. It focuses on Lope de Vega's 1621 La vengadora de las mujeres as case-study and analyses the role of Julio, the play's criado, as enacted by a gracioso. Methodologically, this study is framed within the parameters of Queer theory. It employs both socio-historical and aesthetic early modern sources to reimagine a particular staging of the play. These are cases against sodomy from Spain's Inquisition archive; definitions from Covarrubias' Tesoro de la lengua castellana; two entremeses by Quevedo; Espinel's Sátira a las damas de Sevilla; and Rubens' painting El rapto de Ganímedes. Overall, the textual analysis of Lope's play and its comparison with these resources show that the acting of 'queerness' at the corrales must have been extremely histrionic to fulfill comedic and ideological effects. The paper argues that, throughout the performance, the gracioso would have parodied the vocal and gestural vocabulary of homosexuality and effeminacy in Spanish society to construct a laughable but also problematic stage version of the marión. He would have employed a high timbre, blushing, a side jerk of his neck, head rigidity, secret hand expressions, and an emphasis on his legs, hips, and buttocks in order to make the audience both laugh and reflect on this social type. The combination of these features would have brought Lope's public close to similar complex social phenomena as those constantly treated in contemporary theaters and other media: same-sex desire, gender fluidity and performativity, queerness, and the abuse suffered by queer individuals.
Neoantigen mRNA vaccines and A2A receptor antagonism: A strategy to enhance T cell immunity
Creators: name: Imani, Saber
name: Kaboli, Parham Jabbarzadeh
name: Babaeizad, Ali
name: Maghsoudloo, Mazaher
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Cell Biology
subject: Pharmacology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Computational Biology

description: Although neo-antigen mRNA vaccines are promising for personalized cancer therapy, their effectiveness is often limited by the immunosuppressive tumor microenvironment (TME). The adenosine A2A receptor (A2AR) inhibits dendritic cell (DC) function and weakens antitumor T cell responses through hypoxia-driven mechanisms within the TME. This review explores a novel strategy combining neo-antigen mRNA vaccines with A2AR antagonists (A2ARi). By targeting A2AR, this approach reduces TME-induced immunosuppression, enhances DC activation, and improves neo-antigen presentation. The review also discusses lipid nanoparticles (LNPs) to co-deliver A2ARi and mRNA vaccines, optimizing their effectiveness. The integration of neo-antigen mRNA-LNPs with A2ARi modulation offers a promising strategy to overcome immunosuppression, stimulate DC activation, and achieve precise anti-tumor responses with minimal off-target effects. This synergy represents significant progress in cancer immunotherapy, advancing the potential for personalized neoantigen therapies.
The Attenuated Brucella abortus Strain 19 Invades, Persists in, and Activates Human Dendritic Cells, and Induces the Secretion of IL-12p70 but Not IL-23
Creators: name: Weinhold, Mario
name: Eisenblätter, Martin
name: Jasny, Edith
name: Fehlings, Michael
name: Finke, Antje
name: Gayum, Hermine
name: Rüschendorf, Ursula
name: Viveros, Pablo Renner
name: Moos, Verena
name: Allers, Kristina
name: Schneider, Thomas
name: Schaible, Ulrich E.
name: Schumann, Ralf R.
name: Mielke, Martin
name: Ignatius, Ralf
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2013
Subjects: subject: 610 Medizin

description: Background: Bacterial vectors have been proposed as novel vaccine strategies to induce strong cellular immunity. Attenuated strains of Brucella abortus comprise promising vector candidates since they have the potential to induce strong CD4+ and CD8+ T-cell mediated immune responses in the absence of excessive inflammation as observed with other Gram-negative bacteria. However, some Brucella strains interfere with the maturation of dendritic cells (DCs), which is essential for antigen-specific T-cell priming. In the present study, we investigated the interaction of human monocyte-derived DCs with the smooth attenuated B. abortus strain (S) 19, which has previously been employed successfully to vaccinate cattle. Methodology/Principal findings: We first looked into the potential of S19 to hamper the cytokine-induced maturation of DCs; however, infected cells expressed CD25, CD40, CD80, and CD86 to a comparable extent as uninfected, cytokine-matured DCs. Furthermore, S19 activated DCs in the absence of exogeneous stimuli, enhanced the expression of HLA-ABC and HLA-DR, and was able to persist intracellularly without causing cytotoxicity. Thus, DCs provide a cellular niche for persisting brucellae in vivo as a permanent source of antigen. S19-infected DCs produced IL-12/23p40, IL-12p70, and IL-10, but not IL-23. While heat-killed bacteria also activated DCs, soluble mediators were not involved in S19-induced activation of human DCs. HEK 293 transfectants revealed cellular activation by S19 primarily through engagement of Toll-like receptor (TLR)2. Conclusions/Significance: Thus, as an immunological prerequisite for vaccine efficacy, B. abortus S19 potently infects and potently activates (most likely via TLR2) human DCs to produce Th1-promoting cytokines.
FliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila
Creators: name: Schulz, Tino
name: Rydzewski, Kerstin
name: Schunder, Eva
name: Holland, Gudrun
name: Bannert, Norbert
name: Heuner, Klaus
Publisher: name: Robert Koch-Institut, Biologische Sicherheit
Year: 2012
Subjects: subject: Transmission
subject: Molecular Sequence Data
subject: Sequence Alignment
subject: Legionella pneumophila/pathogenicity
subject: Bacterial Proteins/metabolism
subject: Legionella pneumophila/genetics
subject: Legionella pneumophila/metabolism
subject: Bacterial Proteins/genetics
subject: Base Sequence
subject: Flagella/genetics
subject: Flagellin/metabolism
subject: Gene Expression Profiling
subject: Gene Expression Regulation Bacterial
subject: Gene Knockout Techniques
subject: Legionella pneumophila/ultrastructure
subject: Microbial Viability/genetics
subject: Microscopy Electron
subject: Mutation
subject: Regulon/genetics
subject: Sigma Factor/genetics
subject: Sigma Factor/metabolism
subject: Transcription Factors/genetics
subject: Transcription Factors/metabolism
subject: Virulence/genetics
subject: 610 Medizin

description: In Legionella pneumophila, the regulation of the flagellum and the expression of virulence traits are linked. FleQ, RpoN and FliA are the major regulators of the flagellar regulon. We demonstrated here that all three regulatory proteins mentioned (FleQ, RpoN and FliA) are necessary for full in vivo fitness of L. pneumophila strains Corby and Paris. In this study, we clarified the role of FleQ for fliA expression from the level of mRNA toward protein translation. FleQ enhanced fliA expression, but FleQ and RpoN were not necessary for basal expression. In addition, we identified the initiation site of fliA in L. pneumophila and found a putative σ(70) promoter element localized upstream. The initiation site was not influenced in the ΔfleQ or ΔrpoN mutant strain. We demonstrated that there is no significant difference in the regulation of fliA between strains Corby and Paris, but the FleQ-dependent induction of fliA transcription in the exponential phase is stronger in strain Paris than in strain Corby. In addition, we showed for the first time the presence of a straight hook at the pole of the non-flagellated ΔfliA and ΔfliD mutant strains by electron microscopy, indicating the presence of an intact basal body in these strains.
Gum: A Smart System for Seniors with Diabetes
Creators: name: Huang, Aijun
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Fine arts

description: Diabetes is a prevalent disease nowadays, and it is a big challenge, especially for seniors. The biggest challenge for seniors with diabetes is that they need to prick their fingers to test their blood which is painful and horrible. Also, the current glucose meter does not make good use of the glucose data to help them better treat the diabetes. Also, seniors live alone and lag off behind the diabetes information & technology. Therefore, based on seniors’ characteristics, I want to employ new technologies, such as data visualization and AI technology, in the design to help them manage their diabetes more easily.
 Through the literature review, I learned the disease information of diabetes, investigated the diabetes situation in the seniors’ group, and studied the seniors’ characteristics, which can make the designs more suitable for seniors. To better understand diabetic seniors’ conditions, needs and wishes, I took part in several diabetes events in Lafayette Indiana, volunteered in the retirement village and conducted a series of interviews in these two settings. By analyzing the peer products, daily self-measurement of my own sugar level and keeping diaries, I learned what do the similar products look like, got some inspiration from them and found problems in the current products. After drawing a bunch of sketches to explore the idea, HTA chart, wireframe, low-fidelity prototype and mockups were developed in the first design iteration. I came up with the smart product system, based on the seniors’ characteristics, combined with new technologies to help seniors with diabetes easily manage their diabetes. Then I conducted the usability testing with the prototype & physical models to refine my design. Finally, usability testing was conducted again to make sure my products provide a pleasant experience for seniors with diabetes. With this smart system, testing blood becomes a happy & relaxing experience and seniors can join the diabetes group to support each other. Moreover, Seniors with diabetes can get feedback and suggestions from the system.
Additional file 1 of Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
Creators: name: Soldano, Stefano
name: Smith, Vanessa
name: Montagna, Paola
name: Gotelli, Emanuele
name: Campitiello, Rosanna
name: Pizzorni, Carmen
name: Paolino, Sabrina
name: Sulli, Alberto
name: Cere, Andrea
name: Cutolo, Maurizio
Publisher: name: figshare
Year: 2024
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Supplementary Material 1
Queer Social Counting and the Generational Transitions of Michael Field
Creators: name: Kahrmann Huseby, Amy
Publisher: name: Humanities Commons
Year: 2018
Subjects: subject: Queer theory
subject: Queer poetry
subject: Logic, Symbolic and mathematical
subject: Poetics
subject: Poetry
subject: Versification
subject: Nineteenth century
subject: Women poets
subject: Women in literature

description: Katherine Cooper and Edith Bradley, the poets who collaborated as Michael Field, occupied several generational thresholds as they were publishing work at the fin de siècle: they were two related women, an aunt and a niece, lesbian partners, writing as one man. Each of those thresholds demanded ontological reorientation from the poets. This paper identifies a pattern of transitions from unification to division and back again throughout Michael Field’s work. A series of generational transitions trouble recent critical assertions of Michael Field’s “idealized intimacy” by acknowledging that the wholeness of certain relationships necessitates fluidity, separation, and division. What’s more, they understood that, for queer couples, “one” and two” demanded a new form of social counting. Cooper and Bradley constructed a distinctly queer model of intimacy in their poetry, one perpetually in transition. For queer individuals, the ability to leave and return to close relationships enables an individual to assert the integrity both of oneself and one’s relationship. By addressing how Michael Field’s poetry literally, figuratively, and formally anticipates the lover’s incessant departure and return, this article demonstrates the ways in which these queer poets actuate the complexities of generational transition at the turn of the century.
sj-docx-1-sci-10.1177_00368504211031114 – Supplemental material for A new evaluation and prediction model of sound quality of high-speed permanent magnet motor based on genetic algorithm-radial basis function artificial neural network
Creators: name: Hu, Kai
name: Zhang, Guangming
name: Zhang, Wenyi
Publisher: name: SAGE Journals
Year: 2021
Subjects: Biological Sciences not elsewhere classified

description: Supplemental material, sj-docx-1-sci-10.1177_00368504211031114 for A new evaluation and prediction model of sound quality of high-speed permanent magnet motor based on genetic algorithm-radial basis function artificial neural network by Kai Hu, Guangming Zhang and Wenyi Zhang in Science Progress
Research hotspots and trends in the field of immune checkpoint inhibitors (ICIs) for cervical cancer: A bibliometric study from 2014 to 2024
Creators: name: Shen, Chaoyan
name: Zhang, Juan
name: Zhang, Guanyu
name: Luo, Hao
name: Zhang, Shuangke
name: Yuan, Quan
name: Xu, Wei
name: Wang, Wei
name: Miao, Lele
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Virology

description: In recent years, immune checkpoint inhibitors (ICIs) have emerged as a novel immunotherapeutic approach, offering renewed hope for enhancing cervical cancer patient prognosis. This study represents the inaugural bibliometric analysis of ICIs in the context of cervical cancer, covering the period from 2014 to 2024. A total of 422 articles were identified through the Web of Science Core Collection database, amassing 10,977 citations, with a consistent annual increase in the number of publications. The leading contributors in terms of countries, institutions, journals, and authors included China, the University of Texas System, Frontiers in Oncology, and Bradley J. Monk, respectively. The journal with the highest frequency of citation and co-citation was Journal of Clinical Oncology. The researchers with the highest number of citations and co-citations were Sarina A Piha-Paul and Krishnansu S Tewari respectively. The keyword cluster analysis identified four main research directions. Furthermore, literature co-citation analysis and burst citation analysis revealed three research hotspots and four potential emerging topics within this domain, respectively. This study provides valuable reference and enlightenment for researchers in this field. As research progresses, ICIs are anticipated to offer significant hope and breakthroughs in the treatment of cervical cancer.
sj-docx-3-msj-10.1177_13524585211031128 – Supplemental material for Risk of depression in multiple sclerosis across disease-modifying therapies
Creators: name: Longinetti, Elisa
name: Frisell, Thomas
name: Englund, Simon
name: Reutfors, Johan
name: Fang, Fang
name: Piehl, Fredrik
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care

description: Supplemental material, sj-docx-3-msj-10.1177_13524585211031128 for Risk of depression in multiple sclerosis across disease-modifying therapies by Elisa Longinetti, Thomas Frisell, Simon Englund, Johan Reutfors, Fang Fang and Fredrik Piehl in Multiple Sclerosis Journal
SYSTEM DESIGN AND DEVELOPMENT FOR VISUAL PROGRAMMING OF ROBOT-IOT WORKFLOWS
Creators: name: Rao, Pawan Sudhindra
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Mechanical engineering not elsewhere classified

description: Autonomous Mobile Robots (AMR) and IoT (Internet of Things) devices have substantial potential to increase productivity in Small and Medium Enterprises (SME). However, factors such as high costs involved in setting up and maintaining AMR automation and deficit of programming expertise among factory workers render AMR automation uneconomical for SMEs.
Visual Programming can be used in the spatial context of the operating environment to enable closer mental models at the right level of abstraction for novice programmers. In this thesis, we develop a system for deploying a Spatially Situated Visual Language (SSVL) for programming robot-IoT workflows. To address the challenges of interoperability, scalability, and versatility of industrial machinery, we develop a novel communication protocol based on the Resource Description Framework (RDF). Our communication protocol forms the basis of a system architecture that integrates SSVL, IoT devices, and mobile robots that enables factory workers to program AMR workflows. We design, implement and validate the system and the architecture following the systems engineering approach. To evaluate the system developed in an industrial context, we deploy the system to author AMR workflows for material handling application for an SME painting factory.
sj-pdf-1-qhr-10.1177_10497323211016807 – Supplemental material for Playing With Peers: Exploring Peer Support Mechanisms of a Type 2 Diabetes-Specific Board Game
Creators: name: Lindgreen, Pil
name: Stenov, Vibeke
name: Willaing, Ingrid
name: Basballe, Henning Grubb
name: Joensen, Lene Eide
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111099 Nursing not elsewhere classified
subject: FOS: Health sciences
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology

description: Supplemental material, sj-pdf-1-qhr-10.1177_10497323211016807 for Playing With Peers: Exploring Peer Support Mechanisms of a Type 2 Diabetes-Specific Board Game by Pil Lindgreen, Vibeke Stenov, Ingrid Willaing, Henning Grubb Basballe and Lene Eide Joensen in Qualitative Health Research
Methicillin-resistente Staphylococcus aureus (MRSA) in der medizinischen Rehabilitation
Creators: name: Hergenröder, H.
name: Mielke, Martin
name: Höller, C.
name: Herr, C.
Publisher: name: Robert Koch-Institut, Infektionskrankheiten / Erreger
Year: 2012
Subjects: subject: Methicillin-resistente Staphylococcus aureus (MRSA)
subject: Medizinische Rehabilitation
subject: Risikobasiertes Screening
subject: Risikoanalyse
subject: Risikoadaptierte Präventionsmaßnahmen
subject: Methicillin-resistant Staphylococcus aureus (MRSA)
subject: Medical rehabilitation
subject: Risk based screening
subject: Risk analysis
subject: Risk based preventive measures
subject: 610 Medizin

description: Reha-Kliniken legen im Umgang mit Methicillin-resistentem Staphylococcus aureus (MRSA) häufig das Hygienemanagement der akutmedizinischen Versorgung zugrunde, was Patienten mit positivem MRSA-Status den Zugang in die stationäre Rehabilitation erschwert. In einer Arbeitsgruppe der Bayerischen Landesarbeitsgemeinschaft Multiresistente Erreger (LARE) wurde die Problematik auf Basis einer systematischen Literaturrecherche, der Gründung eines Expertengremiums sowie der Auswertung vorliegender Hygienepläne analysiert und ein Rahmenhygieneplan (RHP) zum Thema MRSA entworfen. Der Entwurf positioniert die stationäre Rehabilitation in einem Korridor zwischen den infektionspräventiven Anforderungen in der akutstationären Versorgung und denen in Einrichtungen der stationären Pflege (Infektionsprävention in Heimen). Als Ausgangspunkt der Festlegung von Maßnahmen wird ein Leitfaden für die ärztliche Risikoanalyse vorgestellt. Zu spezifischen Risikosituationen in der Rehabilitation werden exemplarisch Risikoanalyse und -bewertung mit Blick auf das jeweils angemessene Schutzziel durchgeführt und daraus Präventionsmaßnahmen abgeleitet. Der vorgelegte Beitrag stellt das Schutzziel medizinische Rehabilitation gleichberechtigt neben die Infektionsprävention und versucht nachvollziehbar und exemplarisch darzulegen, wie dem Infektionsschutz risikoadaptiert Rechnung getragen werden kann.
description: Rehabilitation facilities often apply the same standards for management of methicillin-resistant Stapylococcus aureus (MRSA) carriers as acute care hospitals. This makes it difficult to ensure access to the facilities and adequate rehabilitation for carriers. A working group of the Bavarian state committee for multiresistant pathogens addressed these problems by a systematic review of literature, expert group meetings and evaluation of existing hygiene plans. Thereby a model hygiene plan for rehabilitation facilities concerning management of MRSA carriers was derived. The management is based on physician risk assessment blending standards applied in acute and long-term care facilities. For rehabilitation typical risk scenario examples of risk analyses are given. The preventive measures are based on the respective objectives of protection. The risk analysis which gives the basis for the model hygiene plan described in this paper gives equal weight to two main objectives of protection: infection control and medical rehabilitation.
sj-pdf-2-lup-10.1177_09612033211034559 - Supplemental material for Methyl donor micronutrients, CD40-ligand methylation and disease activity in systemic lupus erythematosus: A cross-sectional association study
Creators: name: Vordenbäumen, Stefan
name: Sokolowski, Alexander
name: Rosenbaum, Anna
name: Gebhard, Claudia
name: Raithel, Johanna
name: Düsing, Christina
name: Chehab, Gamal
name: Richter, Jutta G
name: Brinks, Ralph
name: Rehli, Michael
name: Schneider, Matthias
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111702 Aged Health Care
subject: FOS: Health sciences

description: Supplemental material, sj-pdf-2-lup-10.1177_09612033211034559 for Methyl donor micronutrients, CD40-ligand methylation and disease activity in systemic lupus erythematosus: A cross-sectional association study by Stefan Vordenbäumen, Alexander Sokolowski, Anna Rosenbaum, Claudia Gebhard, Johanna Raithel, Christina Düsing, Gamal Chehab, Jutta G Richter, Ralph Brinks, Michael Rehli and Matthias Schneider in Lupus
Immersive Virtual Reality Training to Enhance Procedural Knowledge Retention
Creators: name: Zhang, Jun
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Computer graphics

description: Immersive virtual reality (VR) technology has brought many new opportunities for training researchers and students. In the traditional training environment, trainees usually follow verbal instructions (lecture) or visual instructions (video tutorial, job manual) as certain training methods. For this research study, we not only tested how much procedural knowledge the trainees could learn from the VR training compared with traditional media training (video plus instruction manual), we also specifically focused on how well the knowledge could retain in a certain amount of time. The finding of this study shows that VR training can help trainees learn procedural knowledge, and also shows that VR training can help enhance procedural knowledge retention in terms of recall error. However, we did not find any significant difference in recall time between VR training group and traditional media training group.
Development and validation of a nomogram for predicting acute kidney injury in elderly patients in intensive care unit
Creators: name: Zhao, Li
name: Li, Xunliang
name: Zhao, Wenman
name: Wang, Deguang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: This study aimed to develop and validate a nomogram for predicting acute kidney injury (AKI) in elderly patients in the intensive care unit (ICU). Population data regarding elderly patients in ICU were derived from the Medical Information Mart for Intensive Care IV database from 2008 to 2019. The nomogram model was constructed from the training set using LASSO regression and logistic regression analysis, and the performance of the model was evaluated by decision curve analysis, calibration curve, and receiver operating characteristic (ROC) curve. According to inclusion and exclusion criteria, 14,373 elderly ICU patients were studied, of which 10,061 (70%) were assigned to the training set, and 4,312 (30%) were allocated to the validation set. Multivariate logistic analysis revealed that age, weight, myocardial infarction, congestive heart failure, dementia, diabetes, paraplegia, cancer, sepsis, body temperature, blood urea nitrogen, mechanical ventilation, urine volume, Sequential Organ Failure Assessment (SOFA) score, and Simplified Acute Physiology Score II (SAPS II) were independent risk factors for AKI in elderly ICU patients. The AUC values for the 15-factor nomogram were 0.812 (95% CI 0.802–0.822) and 0.802 (95% CI 0.787–0.818) in the training and validation sets, respectively. For clinical application, a simplified nomogram was constructed, which included age, weight, urine volume, SOFA score, and SAPS II, with the AUCs of 0.780 (95% CI 0.769–0.790) and 0.776 (95% CI 0.760–0.793), respectively. Calibration curve and decision curve analyses confirmed the models’ high prediction accuracy and clinical value. The nomogram developed in this study shows excellent predictive performance for AKI in elderly patients in the ICU.
Plädoyer für STIKO-Empfehlungen
Creators: name: Falkenhorst, Gerhard
name: Leidel, Jan
name: Bogdan, Christian
Publisher: name: Robert Koch-Institut, Infektionsepidemiologie
Year: 2017
Subjects: subject: 610 Medizin

description: Einblick in die Entscheidungswege der STIKO für die Pneumokokken-Impfung von Senioren und Risikogruppen sowie Erwiderung der daran geäußerten Kritik.
Prevention of herpes zoster in acquired immunocompromised conditions: Review of updates and perspectives from Hong Kong
Creators: name: Yap, Desmond Y. H.
name: Chan, Gordon C. K.
name: Ho, So
name: Wong, Raymond S. M.
name: Chan, Stephen L.
name: Lee, Victor H. F.
name: Lam, Wilson
name: Li, Philip H.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Neuroscience
Biotechnology
Cancer
Science Policy

description: Patients with acquired immunocompromising conditions face considerable risk of developing herpes zoster (HZ). Based on the underlying medical conditions and degree of immune dysfunction, these patients require tailored strategies for HZ prevention. In Hong Kong, there is currently a lack of guidelines addressing the unique needs of this vulnerable population, including the use of prophylactic measures such as antivirals and vaccines. An expert panel comprising clinical immunologists, nephrologists, infectious diseases specialists, rheumatologists, hematologists and oncologists in Hong Kong met to review current literature and international guidelines to propose a locally adapted decision-making framework for HZ prophylaxis, in patients with acquired immunocompromised conditions. This article summarizes the consensus and presents a guiding criteria for clinicians to navigate the complexities associated with HZ prevention, in the context of acquired immunodeficiency.
AI, Theater, and Interface Theory, keynote at Imaging Across Time: Wenshan International Conference, National Chengchi University, Taipei, Taiwan, November 18, 2023
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Artificial intelligence
subject: Shakespeare, William, 1564-1616
subject: Theater
subject: Digital humanities
subject: Educational technology
subject: Social justice
subject: Critical race theory

description: What happens when AI goes to theatre with human audiences? Generative AI's natural-language conversational interface has frequently been cast as an anthropomorphic interface. In performance, digital screen as interface has evolved from a vehicle for dramatic messages to a meaning-making agent with an anthropomorphic presence. While the tendency to anthropomorphize this technology is problematic, ChatGPT can be seen as a ghost of the publics, a synthetic version of the publics, or a shadow public.        In her keynote lecture, "Screen as Anthropomorphic Interface: Remediated Performance and Generative Artificial Intelligence," Alexa Alice Joubin argued that screens are a site where cultural and performative meanings are generated and negotiated. She uses interface theories and performance studies methods to analyze the outputs of AI.       ::::      YouTube: https://youtu.be/Bi9a9TBtrow
Social Inequalities and Depressive Symptoms in Adults: The Role of Objective and Subjective Socioeconomic Status
Creators: name: Hoebel, Jens
name: Maske, Ulrike E.
name: Zeeb, Hajo
name: Lampert, Thomas
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: 610 Medizin

description: Background: There is substantial evidence that lower objective socioeconomic status (SES)—as measured by education, occupation, and income—is associated with a higher risk of depression. Less is known, however, about associations between perceptions of social status and the prevalence of depression. This study investigated associations of both objective SES and subjective social status (SSS) with depressive symptoms among adults in Germany. Methods: Data were obtained from the 2013 special wave of the German Health Update study, a national health survey of the adult population in Germany. Objective SES was determined using a composite index based on education, occupation, and income. The three single dimensions of the index were also used individually. SSS was measured using the MacArthur Scale, which asks respondents to place themselves on a 10-rung ‘social ladder’. Regression models were employed to examine associations of objective SES and SSS with current depressive symptoms, as assessed with the eight-item Patient Health Questionnaire depression scale (PHQ-8 sum score ≥10). Results: After mutual adjustment, lower objective SES and lower SSS were independently associated with current depressive symptoms. The associations were found in both sexes and persisted after further adjustment for sociodemographic factors, long-term chronic conditions, and functional limitations. Mediation analyses revealed a significant indirect relationship between objective SES and depressive symptoms through SSS. When the three individual dimensions of objective SES were mutually adjusted, occupation and income were independently associated with depressive symptoms. After additional adjustment for SSS, these associations attenuated but remained significant. Conclusions: The findings suggest that perceptions of low social status in adults may be involved in the pathogenesis of depression and play a mediating role in the relationship between objective SES and depressive symptoms. Prospective studies are needed to establish the direction of effects and to address questions of causality.
Human papillomavirus vaccination at age 9 or 10 years to increase coverage – a narrative review of the literature, United States 2014–2024
Creators: name: Brewer, Sarah K.
name: Stefanos, Ruth
name: Murthy, Neil C.
name: Asif, Amimah F.
name: Stokley, Shannon
name: Markowitz, Lauri E.
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Science Policy

description: The Advisory Committee on Immunization Practices recommends routine human papillomavirus (HPV) vaccination at 11–12 years; the series can begin at age 9. U.S. HPV vaccination coverage is lower than other adolescent vaccinations. One proposed strategy to increase coverage is initiation at 9–10 years. We systematically reviewed studies addressing vaccination at age 9 to identify and evaluate evidence regarding potential programmatic advantages. Among 30 publications from 2014 to 2024 there were retrospective cohort studies (N = 11), intervention studies with a component focused on vaccination at 9–10 (N = 12), and studies of feasibility or acceptability by providers or caregivers (N = 7). While retrospective analyses found earlier initiation associated with completion, limitations in methodology preclude a cause-and-effect interpretation. Impact of age 9 vaccination is difficult to isolate in intervention studies that had multiple components. While initiating vaccination at age 9 is feasible, questions remain regarding the benefit of this approach to increase coverage.
sj-pdf-2-jtr-10.1177_00472875211028321 – Supplemental material for Do Regional Trade Agreements Enhance International Tourism Flows? Evidence from a Cross-Country Analysis
Creators: name: Khalid, Usman
name: Okafor, Luke Emeka
name: Burzynska, Katarzyna
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 150310 Organisation and Management Theory
subject: FOS: Economics and business
subject: 150402 Hospitality Management

description: Supplemental material, sj-pdf-2-jtr-10.1177_00472875211028321 for Do Regional Trade Agreements Enhance International Tourism Flows? Evidence from a Cross-Country Analysis by Usman Khalid, Luke Emeka Okafor and Katarzyna Burzynska in Journal of Travel Research
Health monitoring and health indicators in Europe
Creators: name: Fehr, Angela
name: Lange, Cornelia
name: Fuchs, Judith
name: Neuhauser, Hannelore
name: Schmitz, Roma
Publisher: name: Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
Year: 2017
Subjects: subject: HEALTH MONITORING
subject: EUROPE
subject: INDICATORS
subject: HEALTH REPORTING
subject: CHRONIC DISEASES
subject: 610 Medizin

description: Demographic change, new health threats and inequalities in health and healthcare provision in and between European Union (EU) member states pose a great challenge to European health care systems. Not only for these reasons does it make sense to collect comparable European health data. Such information provides insights on the distribution of risk and protection factors, the prevalence of chronic diseases and the levels of care provided in the member states and supports the planning and implementation of (health) policy measures. Since 2013, in the context of the European Health Interview Survey (EHIS), all EU member states are obliged to collect data on the health status, the provision of healthcare, health determinants and socio-economic conditions of their populations. In Germany, the EHIS is integrated into health monitoring at the Robert Koch Institute (RKI). The RKI is thus Germany’s interface to the European health monitoring presented here. European health monitoring relies on different indicator systems such as the European Core Health Indicators (ECHI), EU social indicators and the health indicators of the European Sustainable Development Strategy. These are based on administrative and survey data, which stem for example from the EHIS or the European Union Statistics on Income and Living Conditions (EU-SILC) survey. Comparative data analyses must take into account the differences between health care systems, socioeconomic conditions and the age structures of societies. Variances in the prevalence of allergies for example are also due to differences in the available diagnostic tools. Significant differences in the prevalence of hypertension in Europe (with a range of 20% for women and 17% for men) are also related to different levels of awareness of hypertension. Comparative analyses can support the planning of and provide information for policy measures, and enhance the sharing of experiences between EU member states. A forthcoming EU regulation aims to harmonise the content of and intervals between health and social statistical data collection. Moreover, plans exist to establish a European Research Infrastructure Consortium (ERIC), which is set to develop and institutionalise European health monitoring.
AI, Theater, and Interface Theory, keynote at Imaging Across Time: Wenshan International Conference, National Chengchi University, Taipei, Taiwan, November 18, 2023
Creators: name: Joubin, Alexa Alice
Publisher: name: National Chengchi University
Year: 2023
Subjects: subject: Digital humanities
subject: Artificial intelligence
subject: Social justice
subject: Educational technology
subject: Shakespeare, William, 1564-1616
subject: Theater
subject: Critical race theory

description: What happens when AI goes to theatre with human audiences? Generative AI's natural-language conversational interface has frequently been cast as an anthropomorphic interface. In performance, digital screen as interface has evolved from a vehicle for dramatic messages to a meaning-making agent with an anthropomorphic presence. While the tendency to anthropomorphize this technology is problematic, ChatGPT can be seen as a ghost of the publics, a synthetic version of the publics, or a shadow public.

 In her keynote lecture, "Screen as Anthropomorphic Interface: Remediated Performance and Generative Artificial Intelligence," Alexa Alice Joubin argued that screens are a site where cultural and performative meanings are generated and negotiated. She uses interface theories and performance studies methods to analyze the outputs of AI. :::: YouTube: https://youtu.be/Bi9a9TBtrow
The Art of Transition: A Design Study for Effective Transition Interventions in Autistic Kids
Creators: name: Nikrahi, Saba
Publisher: name: Purdue University Graduate School
Year: 2019

description: This study is concentrating on the transition process in autistic disorder kids. Transition is characterized as shifting between activities and also in an ongoing task. This transformation appears to be very hard to accomplish for many autistic individuals. The tendency towards sameness and resistance towards any alters in the routines leads to tantrum behaviors, such as kicking, shouting, punching, ... The tantrum behaviors that are the outcome of a transition to a non-preferred activity affects the child’s learning process and brings a lot of pressure and anxiety for both parents and the ASD individual.
The current thesis has focused on obtaining practical ways to facilitate this process and incorporating them into a system design. To fulfill this goal, a precise understanding of the users need was necessary, in addition to choosing the best suitable intervention models and employing them into a design. In the end, a corresponding app, along with a supporting smartwatch, was accomplished through various rounds of usability testing and user studies.