cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
3D blueprint of a backpack and applicator for mounting accelerometer tags on Japanese quail
Creators: name: Barberis, Lucas
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 310901
subject: Animal behaviour

description: This is the blueprint for a backpack for Japanese quail and accelerometer applicator to be 3D-printed in plastic. Two elastic bands are to be inserted at each side of the backpack. These elastic bands are passed around the base of the animal's wings, as shown in Figure 1 of Fonseca et al 2024 "Thanks to repetition, dustbathing detection can be automated combining accelerometry and wavelet analysis" and in [1].The backpack was designed foran TechnoSmArt@ accelerometer-loggers Axyz. The insertion of the accelerometer is performed using a specially designed applicator to ensure synchronization between the acceleration time series and the two video recordings. The applicator works in the following manner: the lever of the applicator is pulled and securely locked. This lever is connected to a spring in contact with the accelerometer. Once the accelerometer is secured inside the applicator, the whole set is connected to the backpack and the lever is released. The spring mechanism propels the accelerometer into the backpack which produces a strong acceleration observed as a sharp peak in the acceleration record. Simultaneously, the applicator mechanism turns on two strings of LED lights within the home box (see Fig. 1B in corresponding paper). After checking that the accelerometer has been properly inserted, the applicator is removed, and a cap is placed to fix the accelerometer in place. Note that the visual signal (i.e. LED lights) triggered by the applicator is captured by both cameras thus making it possible to synchronize, from the video records, the first frame with lights-on with the time on which the first peak in acceleration appears in the accelerometer recordings. The plastic components of the applicator are provided for 3D printing.
Ojos Propios: Photography by and for the People. A Curriculum Guide
Creators: Institute of Latin American Studies
Urban Arts Partnership
Publisher: name: Columbia University
Year: 2017
Subjects: Arts, Latin American
Arts, Caribbean
Photography
Education, Elementary
Education, Secondary

description: This curriculum guide presents exploratory photography as a way to approach Latin American and Caribbean ways of life. The content is based on the work of Ojos Propios, an initiative which originated in Peru. Ojos Propios encourages the youth to capture their surrounding images to create a collective memory that reinforces their identity. In 2015, Ojos Propios Leader Andrés Longhi and his crew traveled to ILAS, Columbia University, and conducted a workshop with New York City's students. This guide provides activities to analyze the outcomes in New York, as well as in other South American countries. The guide was produced by ILAS, in collaboration with Urban Arts Partnership.
A descriptive typology for organizational values
Creators: name: Rushworth, Susan
name: Gillin, Murray
Publisher: name: Swinburne
Year: 2024

description: A study identifying organizational values in emerging companies revealed values that clearly differed in their nature and purpose. A theoretical framework for describing these differences was developed drawing on the distinction made by Dees and Starr (1992) between 'ethical' and 'psychological' values, interpreted as continuum rather than dichotomous choice. Applying this framework to 96 values identified at 14 companies revealed widely differing interpretations of values between companies, simply illustrated as a graphical “profile”. Basic statistical analysis of numeric representations of values orientations suggested that espoused values were more likely to be ethical in orientation whereas implicit values were more likely to be psychological in orientation.
title: Intangible Heritage and Social Change: A Romanian Example
Creators: name: Rus, Alin
Publisher: name: University of Massachusetts Amherst
Year: 2012
Subjects: subject: intangible heritage
subject: ritual
subject: collective memory
subject: Romania
subject: Anthropology
subject: FOS: Sociology

description: In this article we shall emphasize the nature of intangible heritage of a rural ritual based on a case study from a village located in the East of Romania. The ritual considered here is a sitting down event – a cultural form frequently practised in the respective community seven decades ago. This ritual is revived by the villagers with the support of the County Center for the Preservation and Promotion of Traditional Culture Iași and of the Local Mayor’s Office, by the active involvement of the local leaders. The thesis of this article is that in the practice of intangible heritage there are also other motivations apart from the remuneration incentive which should mobilize the members of a community to act together in view of the promotion of their intangible heritage. We will also argue that the criterion of authenticity of the ritual is fulfilled as long as this form of intangible heritage of the rural communities from today’s territory of Romania is reconstructed based on the representation from the collective memory of the community and is revitalized by the active involvement of a group of villagers from the locality. This assertion remains valid even when it is about a ritual which was no longer practiced in that community for almost seven decades. Thus, the practice of the respective ritual comes in agreement with the ideas stipulated in the 2003 Convention for the Safeguarding of Intangible Cultural Heritage, which underlies “the importance of the intangible cultural heritage as a mainspring of cultural diversity” and its important role in “enriching cultural diversity and human creativity.”
'Family comes first': fundraisers' perspectives on charitable bequests
Creators: name: Baker, Christopher
Publisher: name: Swinburne
Year: 2024

description: This exploratory paper examines how fundraisers for charitable organisations in Australia understand influences of charitable giving in the transmission of individual, deceased estates. It utilizes a sub-set of semi-structured interviews conducted as part of a wider study into the place of charitable giving in the intergenerational transfer of wealth. My analysis draws on Mauss’s classic concept of the “‘total’ social phenomena” that underpins the process of gift giving, and on contemporary theory of social capital and trust. The insights of fundraisers suggest that attitudes towards asset transmission and charitable giving are overwhelmingly influenced by expectations of honouring family ties and they are influenced to a far lesser degree by the nature and strength of the relationships individuals have with charitable organisations.
A Technical Overview on Protective Clothing against Chemical Hazards
Creators: name: Khalil, Elias
Publisher: name: figshare
Year: 2015
Subjects: subject: Organic Chemistry
subject: FOS: Chemical sciences
subject: Environmental Chemistry

description: Protection against harmful chemical materials is compulsory in many aspects of everyday life. Proper and adequate protective clothing is desirable during household chores and in industrial, agricultural, and medical work, during military operations; and in response to incidents of terrorism. Different types of materials and garment designs are used in these clothing items, and protection levels vary considerably. Selections must be made as to which items of protective clothing to select for a given situation or environment. Variables to be considered include weight, comfort, level of protection, and the duration of protection required. In addition, the nature of the challenges to be encountered is also of signiﬁcant concern. Due to the huge number of variables involved, numerous levels and types of chemical protective clothing systems has been technologically developed.
Parametrage du deferlement des vagues dans les modeles spectraux: approches semi-empirique et physique (Setting waves in the spectral model: semi-empirical and physical approaches)
Creators: name: Filipot, Jean-francois
name: Ardhuin, Fabrice
name: Babanin, Alexander
name: Magne, R
Publisher: name: Swinburne
Year: 2024

description: The dissipation of wave energy is generally parameterized empirically with an arbitrary separation between white-capping and depth-induced breaking. Here we follow recent developments in phase-averaged spectral models and extend the semi-empirical parameterization to include the loss of short wave energy due to the breaking of longer waves. The physical basis of this parameterization is discussed and an extension is proposed, giving a unified parameterization for both white-capping and depth-induced breaking. That physical formulation is the product of two verifiable quantities that are the energy dissipation rate per unit length of breaking wave front and the breaking probability for each wave scale.
The role of knowledge management in an organsitation's sustainable development
Creators: name: Meer, Rosemary
name: Sukunesan, Suku
Publisher: name: Swinburne
Year: 2024

description: In this research we plan to examine the role that Knowledge Management has in development of sustainable organisations. Further more, we propose to examine whether there are any key factors in the use of Knowledge Management and sustainable development that could be used to provide a measure on the impact Knowledge Management has in achieving sustainability. The research project is an exploratory study using a case study approach. This method has been chosen due to the limited amount of literature available on the use of Information Technology and particularly Knowledge Management in sustainable development. By undertaking a case study approach, there is the flexibility to examine what is actually happening and adjust the developing theories according to the research rather than attempting to prove predefined theories. The significance of this study is the opportunity to see how much impact Knowledge Management can make in the process of reengineering an organisation along sustainable goals. It also contributes to the body of knowledge being put forward on the role of IT in sustainable development.
ICT as an effective education vehicle for socially responsible culture in the office environment
Creators: name: Gill, Robert
name: Kwansah-Aidoo, Kwamena
Publisher: name: Swinburne
Year: 2024

description: Increasing numbers of Australian organisations are paying greater attention to motivating and effectively utilising the skills of their employees. Employer of Choice (EOC) programs are one way of achieving these goals. EOC reflects the value and importance organisations place on their key stakeholders---their staff. Many organisations are working hard to acquire EOC status. This paper suggests Computer Assisted Learning (CAL), which embraces the constructivists' principles of adult learning can provide the ideal platform for educating a large office-based staff about an organisation's EOC program. CAL also enables individually-tailored learning along with additional opportunities to reflect an organisation's branding and culture.
Amyloid in dementia associated with familial FTLD: not an innocent bystander
Creators: name: Naasan, Georges
name: Rabinovici, Gil D.
name: Ghosh, Pia
name: Elofson, Jonathan D.
name: Miller, Bruce L.
name: Coppola, Giovanni
name: Karydas, Anna
name: Fong, Jamie
name: Perry, David
name: Suzee E. Lee
name: Yokoyama, Jennifer S.
name: Seeley, William W.
name: Kramer, Joel H.
name: Weiner, Michael W.
name: Schuff, Norbert
name: Jagust, William J.
name: Grinberg, Lea T.
name: Mochtar Pribadi
name: Zhongan Yang
name: Sears, Renee
name: Klein, Eric
name: Wojta, Kevin
name: Rosen, Howard J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Biological Sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Chemistry
subject: Neuroscience
subject: Cell Biology
subject: Medicine

description: Patients with frontotemporal lobar degeneration (FTLD) can show superimposed amyloid pathology, though the impact of amyloid on the clinical presentation of FTLD is not well characterized. This cross-sectional case–control study compared clinical features, fluorodeoxyglucose-positron emission tomography metabolism and gray matter volume loss in 30 patients with familial FTLD in whom amyloid status was confirmed with autopsy or Pittsburgh compound B-PET. Compared to the amyloid-negative patients, the amyloid-positive patients performed significantly worse on several cognitive tests and showed hypometabolism and volume loss in more temporoparietal regions. Our results suggest that in FTLD amyloid positivity is associated with a more Alzheimer’s disease-like pattern of neurodegeneration.
Adenda a la Guía docente de Juegos Motores
Creators: name: Fernández-Revelles, Andrés B.
name: , Cueto-Martín
name: García-Ramos, Amador
Publisher: name: Zenodo
Year: 2020
Subjects: Motor Games; Juegos Motores; Guia Docente; Teacher's guide; COVID-19

description: Adenda a la guía docente para la asignatura Juegos Motores perteneciente al Grado en Ciencias de la Actividad Física y el Deporte. Adenda provocada por el COVID-19 y la correspondiente adaptación por el confinamiento. Aprobada el 29 de abril de 2020
Bistable dissipative soliton in cubic-quintic nonlinear medium with multiphoton absorption and gain dispersion
Creators: name: Gurkirpal Singh Parmar
name: Soumendu Jana
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Chemistry
subject: Medicine
subject: Physics
subject: Engineering
subject: Biochemistry
subject: Biophysics

description: We studied the propagation of optical pulse in a dissipative cubic-quintic nonlinear medium with multiphoton absorption and gain dispersion. Variational method in conjugation with Rayleigh dissipative function is used to analytically solve the governing complex cubic-quintic Ginzburg–Landau equation. Three cases of multiphoton absorption are studied: (i) two-photon absorption (TPA), (ii) three-photon absorption (3PA) and (iii) both TPA and 3PA. For all three cases, the pulse intensity decays and width broadens. The greater the gain dispersion, the wider the pulse. Increasing quintic nonlinearity marginally affects pulse amplitude but significantly reduces pulse broadening. TPA and 3PA, which are functions of positive imaginary parts of, respectively, third- and fifth-order susceptibility, individually cause pulse decay and pulse broadening. Thus, their combination only expedites pulse degradation. Conversely, negative imaginary part of fifth-order susceptibility may lead to an effect that impedes pulse degradation. Matching numerical results are obtained that validates the entire analytical outcome. A suitable gain can arrest both pulse broadening and decay. Such dissipative solitonic pulses, bistable owing to quintic nonlinearity, are found for all cases.
An integrative model of design thinking
Creators: name: Camacho, Maria
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 330310
subject: Interaction and experience design

description: This paper presents a study and synthesis of commonalities and variations among effective approaches of design thinking, based on interviews to twelve global experts. Common fundamental knowledge is needed, as design thinking increasingly becomes a field of knowledge in its own and a liberal art. Therefore, this study proposes an Integrative Model of Design Thinking, focusing on principles underlying current methods and tools, and integrating complementary aspects from different approaches into an overarching view of design thinking. The author's expectation is for this Model to contribute to the establishment of a field of design thinking and support its multidisciplinary practice. Furthermore, this paper provides significant insights into the nature of design thinking, according to the convictions of experts who are at the forefront of its research and practice. Further research is needed to expand on some of the principles presented.
Adenda a la Guía docente de Juegos Motores
Creators: name: Fernández-Revelles, Andrés B.
name: , Cueto-Martín
name: García-Ramos, Amador
Publisher: name: Zenodo
Year: 2020
Subjects: Motor Games; Juegos Motores; Guia Docente; Teacher's guide; COVID-19

description: Adenda a la guía docente para la asignatura Juegos Motores perteneciente al Grado en Ciencias de la Actividad Física y el Deporte. Adenda provocada por el COVID-19 y la correspondiente adaptación por el confinamiento.
Landscapes of polyphase glaciation: eastern Hellas Planitia, Mars
Creators: name: Brough, Stephen
name: Hubbard, Bryn
name: Souness, Colin
name: Grindrod, Peter M.
name: Davis, Joel
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: The mid-latitudes of Mars host numerous ice-related landforms that bear many similarities to terrestrial ice masses. This collection of landforms, termed viscous flow features (VFFs), is composed primarily of H2O ice and shows evidence of viscous deformation. Recent work has hypothesised that VFFs are the diminishing remains of once larger ice masses, formed during one or more previous ice ages, and the landscape therefore records evidence of polyphase glaciation. However, debate persists concerning the former extent and volume of ice, and style of former glaciations. The accompanying map (1:100,000 scale) presents a geomorphic and structural assessment of a glacial landscape in eastern Hellas Planitia, Mars. Here, we present a description of the features identified, comprising four geomorphic units (plains, lobate debris apron, degraded glacial material, and glacier-like form) and 16 structures (craters, moraine-like ridges, flow unit boundaries, arcuate transvers structures, longitudinal surface structures, ring-mold craters, terraces, medial moraine-like ridges, raised textured areas, flow-parallel and flow-transverse lineations, crevasses and crevasse traces, and ridge clusters).
The development of generic span tables for cold formed steel studs in residential and low-rise construction
Creators: name: Watson, K.
name: Kelly, H.
name: Pham, Linh
name: Gad, Emad
Publisher: name: Swinburne
Year: 2024

description: The process of roll forming of steel provides the designer with virtually unlimited possibilities in the shape of the section which has led to the development a wide range of very efficient proprietary sections. However this has made it difficult for building designers and engineers to design and specify a house or other low-rise structure given the number of different sections available and complexity of the cold-formed steel standard AS/NZS 4600. The sections commonly used in Australia and America were reviewed and a wide range of sections were chosen to cover the range of sections commonly used. They covered lipped and plain C channels made from G300 and G550 steel. These sections were investigated to determine their load carrying capacity. Factors evaluated included effective lengths for both clad and unclad studs, width of studs, height of walls, connection types, and influence of noggings. From this analysis a standard stud was chosen which was specified in tenns of load capacity rather than section shape and thickness. This allows manufacturers to develop innovative new sections for which the span tables permit valid selection. It also allows last minute changes and substitutions to be made on site simply and quickly. The load combinations are determined from the NASH Standard - Residential and Low-rise Steel Framing Part 1 Design Criteria. The critical load cases are identified and discussed. Examples of the resulting span tables are given together with typical installation details.
Geotechnical testing to determine the suitability of biosolids for embankment fill
Creators: name: Suthagaran, V.
name: Arulrajah, Arul
name: Lamborn, Julia
name: Wilson, John
Publisher: name: Swinburne
Year: 2024

description: Biosolids are an end product of municipal wastewater treatment and contain many of the constituents removed from the influent wastewater. The use of biosolids and other waste materials in a sustainable manner is currently being investigated in several countries around the world. A series of field tests were undertaken on biosolids stockpiles at Western Treatment Plant in Victoria. Following the field tests and sampling geotechnical laboratory tests were undertaken to assess the viability of using biosolids as fill material for embankment fills. Geotechnical properties of untreated biosolids and stabilised biosolids with 1%, 3% and 5% of cement were obtained from the laboratory tests. The field and laboratory test results were compared with the existing local road authority specification for fill material.
Shaking table test of full-scale brick veneer house
Creators: name: Heath, David
name: Gad, Emad
name: Wilson, John
Publisher: name: Swinburne
Year: 2024

description: Many of existing reinforced concrete (RC) frames which designed according to old seismic codes or for gravity loads has insufficient lateral load-carrying capacity and limited ductility. All of these RC frames can be defined as nonductile RC frames, and needs to be strengthened for reducing the risk of severe damage or even collapses in the future strong earthquakes. To date, the use of externally bonded fibre reinforced polymers (FRP) composites wraps is an effective means for rehabilitation and seismic retrofit of RC structures. To investigate and evaluate the seismic performance of nonductile RC frames retrofitted using FRP, the shaking table test of two 1/2 scale 4-storey and 2-bay bare and strengthened nonductile RC frames was conducted. The strengthened frame was retrofitted at the joint regions of first and second storey, due to the test results of bare frame shows that only joint regions of the lower two storeys were seriously damaged. The variation of failure mode, seismic response and performance between bare and FRP-retrofitted frame, and the development process from initial damage to failure of structures under different earthquake levels was discussed based on the experimental results. The results show that the seismic performance of retrofitted RC frame is significantly enhanced in comparison with the bare frame. Bare frame failed when the applied peak ground acceleration (PGA) equal to 0.6g, while the retrofitted frame has little damage after applied PGA larger than 1.0g. It also found that the structural horizontal displacement and inter-storey drift ratio of retrofitted frame was much smaller than bare frame at the same earthquake level.
Exploring the basics with circuit simulation: support for self-teaching of electrical engineering fundamentals
Creators: name: Banky, George
Publisher: name: Swinburne
Year: 2024

description: Students enrolled in the first year electrical engineering subject at Swinburne University of Technology were encouraged to use an electronic circuit simulation software, Multisim 10 from National Instruments, for self-teaching while: (i) confirming any qualitatively predicted circuit behaviour, (ii) validating any quantitative results of problem-based activities and (iii) first predicting the cause, then verifying these predictions, for the behaviour of potentially faulty circuit components. The students’ exposure to this software was facilitated, not only by the mandatory purchase of a copy of the software, but by them being timetabled for all their tutorial sessions into a computer laboratory (rather than a conventional classroom) where under academic supervision they were able to work on desktop computers that had preinstalled copies of the said software. Analysis of two surveys and five post-event focus groups clearly revealed general learner acceptance for using the simulation software for self-teaching in both communal and private settings.
Landscapes of polyphase glaciation: eastern Hellas Planitia, Mars
Creators: name: Brough, Stephen
name: Hubbard, Bryn
name: Souness, Colin
name: Grindrod, Peter M.
name: Davis, Joel
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: 20199 Astronomical and Space Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: The mid-latitudes of Mars host numerous ice-related landforms that bear many similarities to terrestrial ice masses. This collection of landforms, termed viscous flow features (VFFs), is composed primarily of H2O ice and shows evidence of viscous deformation. Recent work has hypothesised that VFFs are the diminishing remains of once larger ice masses, formed during one or more previous ice ages, and the landscape therefore records evidence of polyphase glaciation. However, debate persists concerning the former extent and volume of ice, and style of former glaciations. The accompanying map (1:100,000 scale) presents a geomorphic and structural assessment of a glacial landscape in eastern Hellas Planitia, Mars. Here, we present a description of the features identified, comprising four geomorphic units (plains, lobate debris apron, degraded glacial material, and glacier-like form) and 16 structures (craters, moraine-like ridges, flow unit boundaries, arcuate transvers structures, longitudinal surface structures, ring-mold craters, terraces, medial moraine-like ridges, raised textured areas, flow-parallel and flow-transverse lineations, crevasses and crevasse traces, and ridge clusters).
Newsletter 03 - E³UDRES² Ent-r-e-novators: Celebrating Milestones and Future Directions
Creators: name: E³UDRES² Ent-r-e-novators partners
Publisher: name: Zenodo
Year: 2024

description: Newsletter 03 - E³UDRES² Ent-r-e-novators: Celebrating Milestones and Future Directions
The glutaredoxin gene family in wheat functions beyond redox homeostasis regulation
Creators: name: Ziemann, Mark
name: Zachgo, Sabine
name: Bhave, Mrinal
Publisher: name: Swinburne
Year: 2024

description: The main function of glutathione (GSH) in the cell is to act as a redox buffer against irreversible damage to cell machinery caused by a build up of reactive oxygen species (ROS). Other functions of glutathione in the cell include xenobiotic and heavy metal detoxification, signalling in plant-pathogen interactions as well as plant developmental processes and cell cycle control1. Because glutathione can form bonds to thiols of proteins, and can be enzymatically transferred and removed, it provides an interesting way by which protein activity can be modulated as has been shown for NF-κB in humans2 and NPR1 in Arabidopsis3. Glutaredoxins (GRXs) are glutathione dependant oxidoreductase enzymes which mediate the reversible reduction of disulphide bonds of proteins and proteinglutathione mixed disulphides and are found in all freeliving organisms4,2. Apart from their obvious role in the regulation of redox balance, plant glutaredoxins have been shown to bind iron sulphur centres5, regulate defensin expression6 and be crucial for flower development7,8. Glutathionylation is now being seen as a reversible post translational modification analogous to phosphorylation and inherently linked to cellular redox potential. In order to obtain a greater understanding of the role of glutathionylation, it is necessary to study redox active protein families such as glutathione S-transferases (GSTs) and GRXs. This paper describes aspects of GRX gene expression in wheat and the potential role of three GRX genes in inflorescence development.
Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders
Creators: name: Parkin, Georgia M.
name: Udawela, Madhara
name: Gibbons, Andrew
name: Dean, Brian
Publisher: name: Swinburne
Year: 2024

description: Glutamate is the predominant excitatory neurotransmitter in the human brain and it has been shown that prolonged activation of the glutamatergic system leads to nerve damage and cell death. Following release from the pre-synaptic neuron and synaptic transmission, glutamate is either taken up into the presynaptic neuron or neighbouring glia by transmembrane glutamate transporters. Excitatory amino acid transporter (EAAT) 1 and EAAT2 are Na+-dependant glutamate transporters expressed predominantly in glia cells of the central nervous system. As the most abundant glutamate transporters, their primary role is to modulate levels of glutamatergic excitability and prevent spill over of glutamate beyond the synapse. This role is facilitated through the binding and transportation of glutamate into astrocytes and microglia. The function of EAAT1 and EAAT2 is heavily regulated at the levels of gene expression, post-transcriptional splicing, glycosylation states and cell-surface trafficking of the protein. Both glutamatergic dysfunction and glial dysfunction have been proposed to be involved in psychiatric disorder. This review will present an overview of the roles that EAAT1 and EAAT2 play in modulating glutamatergic activity in the human brain, and mount an argument that these two transporters could be involved in the aetiologies of schizophrenia and affective disorders as well as represent potential drug targets for novel therapies for those disorders.
Molecular characterization of Cyclophilin B genes and promoter sequences in wheat and rice
Creators: name: Wu, Huimei
name: Bhave, Mrinal
Publisher: name: Swinburne
Year: 2024

description: The storage proteins (prolamins) of wheat endosperm are commonly grouped into the monomeric gliadins and polymeric glutenins, the latter comprised of low and high molecular weight (LMW and HMW) subunits1, 2. This forms the highly structured protein network (gluten) that determines the viscoelastic properties of the flour which affect its end-uses1, 2, 3. The storage protein bonding, folding, assortment and deposition processes in the endosperm imply significant roles for ER-localised chaperones and ‘foldase’ enzymes, and three groups of proteins are likely involved: the enzymes protein disulphide isomerases (PDI), peptidyl-prolyl cis-trans isomerases (PPIases), and the Binding Protein (BiP)/heat shock protein (Hsp70) chaperones4, 5. The cyclophilins (CyPs), belonging to PPIase class, are of particular interest as preliminary evidence shows their involvement in seed storage protein processes6, 7. The ER-localised Cyps (commonly called CypB) are of particular relevance due to the storage protein folding and assortment processes for both transport pathways initiating and/or occurring in the ER. However, little genetic information exists on genes encoding this ‘foldase’ enzyme, and on the flanking regulatory sequences which might affect the timing, tissue specificity or transcription rates. This work reports on the CypB genes and their promoters in wheat.
The anatomy of Stratesaurus (Reptilia, Plesiosauria) from the lowermost Jurassic of Somerset, United Kingdom
Creators: name: Benson, Roger B J.
name: Evans, Mark
name: Taylor, Michael A.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Evolutionary Biology

description: ABSTRACTWe provide a complete description of one of the oldest plesiosaurians, Stratesaurus taylori from the earliest Hettangian of the United Kingdom. At least 25 apomorphies distinguish S. taylori from the sympatric Thalassiodracon hawkinsii, to which all three specimens of S. taylori were originally referred. Several features of the skull of S. taylori suggest specialization on small prey items, or sieve feeding. In particular, it has anteriorly inclined premaxillary and mesial maxillary teeth and an only weakly heterodont maxillary dentition. This indicates niche partitioning among sympatric small-bodied plesiosaurians: T. hawkinsii has a pronouncedly heterodont dentition. With a body length estimated around 2 m, S. taylori is one of the smallest plesiosaurians, comparable to T. hawkinsii. Our anatomical review of S. taylori suggests difficulty determining its precise phylogenetic affinities. This is consistent with a general lack of phylogenetic resolution among earliest Jurassic plesiosaurians, which may result from missing data on their Triassic ancestry. However, due to its plesiomorphic morphology and well-characterized anatomy, we recommend S. taylori as an ingroup representative of Plesiosauria for future cladistic analyses of Triassic sauropterygians.SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP
Morphometric analysis of the forelimb and pectoral girdle of the Cretaceous ornithopod dinosaur Oryctodromeus cubicularis and implications for digging
Creators: name: Fearon, Jamie L.
name: Varricchio, David J.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Biological Sciences
subject: Ecology
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Physiology
subject: Cell Biology
subject: Biophysics

description: ABSTRACTThe basal ornithopod Oryctodromeus cubicularis was described as burrowing due to its discovery in a burrow structure, and the presence of several morphological features considered consistent with burrowing. Using traditional and geometric morphometric analyses, the morphology of the humerus and scapula of ornithopods, basal ornithischians, and marginocephalians was analyzed to describe and characterize quantitatively the differences between Oryctodromeus and other ornithopods. These differences were then compared with the morphological adaptations for digging in mammals, because there are no adequate analogues for burrowing in extant archosaurs. A canonical variates analysis was also conducted on the geometric morphometric data to determine if phylogeny impacted morphological trends. The humerus of Oryctodromeus is slightly more robust than other basal ornithopods, indicating an adaptation for increased force applied to the humerus. The scapula provides the most compelling morphological support for digging in Oryctodromeus. The large acromion process and prominent scapular spine of Oryctodromeus, as well as the large posteroventrally expanded scapular blade, distinguish the scapula of Oryctodromeus from those of other ornithopods and would have provided surface areas for the attachment of the supracoracoideus, deltoideus clavicularis, and deltoideus scapularis muscles, the latter of which is important in digging in mammals. These features provide evidence for specialization for producing burrows by scratch digging.SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP
Build-a-Calculus: Experimental dietary research on in vitro dental calculus
Creators: name: Bartholdy, Bjørn Peare
name: Reidsma, Femke H
name: Henry, Amanda G
Publisher: name: Zenodo
Year: 2020
Subjects: Dental calculus
Palaeodiet
Oral biofilm
Ancient starch

description: This study presents a model calculus system, which will allow experimental research to be conducted on in vitro dental calculus. We grow oral multispecies biofilms on plastic pegs, which are inoculated with whole saliva and suspended in artificial saliva for 25 days. The mineral composition of the in vitro calculus was verified using FTIR spectroscopy and archaeological and modern reference calculus. The biofilms were submerged in solutions (0.5% w/v) containing wheat and potato starches twice daily for six minutes. Over the course of the experiment the biofilms were exposed to a large quantity of wheat (ca. 45.43×106) and potato (ca. 3.583×106) starch grains, of which only a minor proportion was visible, microscopically, in thecalculus (0.0021% and 0.0018%, respectively). The proportion of small (<20 µm) grains recovered from the calculus for both wheat (0.0034%) and potato (0.0032%), was greater than for large (>20 µm) grains (0.0003% and 0.0007%, respectively). These results suggest that only a minor portion of an individual’s diet is retained in the dental calculus and that there is a size bias in the incorporation of starches, such that larger grains may be underrepresented. This model calculus system can provide the framework to perform controlled experiments addressing fundamental questions and issues concerning dental calculus, which have yet to be explored. These include validation of sampling and extraction methods, the incorporation of dietary and other markers into the calculus matrix, and the effects of taphonomy. This project was funded by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program [grant number STG–677576 (“HARVEST”)].
Boxing kangaroos on wheels: Australian design education, sporting heritage and national identity
Creators: name: Jackson, Simon
Publisher: name: Swinburne
Year: 2024

description: At sporting events world-wide, the image of a boxing kangaroo on a green and gold flag is flown by proud Australian spectators. Australia’s national identity has long been based on sporting prowess, inspiring one influential manufacturer to lament in 1945: 'Great deeds in the realms of war and sport have imbued Australians with a full measure of national pride. We should be no less proud of their industrial history, but unfortunately there are few who appreciate the extent of their achievement in less than 150 years.' Despite these stirring words, it is as a sporting nation that Australians, then and now mostly identify. Happily, however, there have been several occasions where industrial design, manufacturing and sport have met to mutual advantage.
Teaching journalistic practice in a convergent media age: innovations and issues
Creators: name: Bossio, Diana
Publisher: name: Swinburne
Year: 2024

description: In teaching journalistic practice in the higher education sector, practitioners are increasingly encouraged to highlight the profession's transition to a convergent media age. But what does this actually mean in practice? Looking at both the theoretical and practical development of the new post-graduate journalism units at Swinburne University as a case study, this paper aims to compare the traditionally print-based forms of journalistic pedagogy with 'new media' innovations. In doing so, this paper critically discusses new approaches to journalistic pedagogy, and their consequences for the identity and direction of the profession.
The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2
Creators: name: Azfar Jamal
name: Manickavinayaham Swarnalatha
name: Sarwat Sultana
name: Joshi, Prashant
name: Subrat K. Panda
name: Kumar, Vijay
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Cancer
subject: Developmental Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: E3 ubiquitin ligases have been implicated in the ubiquitination and proteasome-mediated degradation of several key regulators of cell cycle. Owing to their pleotropic behavior, E3 ubiquitin ligases are tightly regulated both at transcriptional and post-translational levels. The E3 ubiquitin ligase TRUSS (tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein) which negatively regulates c-Myc, are found down-regulated in most human cancer cell lines. However, the mechanism of regulation of intracellular levels of TRUSS remains elusive. Here we show that TRUSS is expressed majorly during the G1 phase of cell cycle and its level starts to decline with the expression of S-phase specific E3 ligase Skp2. Enforced expression of Skp2 led to a marked increase in the ubiquitination of TRUSS after its phosphorylation by GSK3β and followed by rapid proteolytic degradation. Our co-immunoprecipitation studies suggested a direct interaction between Skp2 and TRUSS through the LRR motif of Skp2. Interestingly, the human tumor samples that exhibited elevated expression of Skp2, showed relatively poor expression of TRUSS. Further, enforced expression of HBx, the oncoprotein of Hepatitis B virus which is known to stabilize c-Myc and enhance its oncogenic potential, led to the intracellular accumulation of TRUSS as well as c-Myc. Apparently, HBx also interacted with TRUSS which negatively impacted the TRUSS-c-Myc and TRUSS-Skp2 interactions leading to stabilization of TRUSS. Thus, the present study suggests that TRUSS is a novel substrate of E3 ligase Skp2 and that disruption of TRUSS-Skp2 interaction by viral oncoproteins could lead to pathophysiological sequelae.
Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis
Creators: name: Lenoir, Olivia
name: Jasiek, Magali
name: Hénique, Carole
name: Guyonnet, Léa
name: Hartleben, Björn
name: Bork, Tillmann
name: Chipont, Anna
name: Flosseau, Kathleen
name: Bensaada, Imane
name: Schmitt, Alain
name: Jean-Marc Massé
name: Souyri, Michèle
name: Huber, Tobias B
name: Pierre-Louis Tharaux
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Physiology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Plant Biology

description: The glomerulus is a highly specialized capillary tuft, which under pressure filters large amounts of water and small solutes into the urinary space, while retaining albumin and large proteins. The glomerular filtration barrier (GFB) is a highly specialized filtration interface between blood and urine that is highly permeable to small and midsized solutes in plasma but relatively impermeable to macromolecules such as albumin. The integrity of the GFB is maintained by molecular interplay between its 3 layers: the glomerular endothelium, the glomerular basement membrane and podocytes, which are highly specialized postmitotic pericytes forming the outer part of the GFB. Abnormalities of glomerular ultrafiltration lead to the loss of proteins in urine and progressive renal insufficiency, underlining the importance of the GFB. Indeed, albuminuria is strongly predictive of the course of chronic nephropathies especially that of diabetic nephropathy (DN), a leading cause of renal insufficiency. We found that high glucose concentrations promote autophagy flux in podocyte cultures and that the abundance of LC3B II in podocytes is high in diabetic mice. Deletion of Atg5 specifically in podocytes resulted in accelerated diabetes-induced podocytopathy with a leaky GFB and glomerulosclerosis. Strikingly, genetic alteration of autophagy on the other side of the GFB involving the endothelial-specific deletion of Atg5 also resulted in capillary rarefaction and accelerated DN. Thus autophagy is a key protective mechanism on both cellular layers of the GFB suggesting autophagy as a promising new therapeutic strategy for DN.
Best publishing practices to improve user confidence in scientific software
Creators: name: Poisot, Timothée
Publisher: name: figshare
Year: 2015
Subjects: subject: Computational Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Computer Software

description: Preprint of a paper (currently in revision at Ideas in Ecology and Evolution) on practices to improve the reliability of scientific software.
Harmonizing the concept of entrepreneurial capacity
Creators: name: Cunningham, Everarda
name: Moroz, Peter
Publisher: name: Swinburne
Year: 2024

description: This paper presents a comparative analysis of two potentially overlapping concepts: entrepreneurial capacity and absorptive capacity. Consideration is given to the complex task of distinguishing a nascent theoretical concept from a mature, empirically tested concept without including the presumptions and bias that accompany the nature of comparisons between two potentially competing scientific paradigms. The approach used to analyse the concepts is developed using literature on theory development and results in providing two overarching categories for examination: relevance and utility. The findings provide evidence to support initial observations as to the relative proximity of both concepts with respect to innovation, but ultimately lend ground to our argument that entrepreneurial capacity is highly distinguishable from absorptive capacity, and that the concepts may actually be complimentary. The implications of these findings are significant to the establishment of entrepreneurial capacity as a distinct concept, but also provide an interesting basis for further exploration of how the opportunity school and emergence school that are prevalent within the field may be ultimately streamlined into an alloyed theory of entrepreneurship and innovation.
title: Carrot :
title: Guidelines for the Conduct of Tests for Distinctness, Uniformity and Stability.
titleType: Subtitle
Creators: name: (:Unas)
Publisher: name: Unknown
Year: 2023

description: The purpose of these guidelines (“Test Guidelines”) is to elaborate the principles contained in the General Introduction (document TG/1/3), and its associated TGP documents, into detailed practical guidance for the harmonized examination of distinctness, uniformity and stability (DUS) and, in particular, to identify appropriate characteristics for the examination of DUS and production of harmonized variety descriptions.
Youth Voices: Rethinking the War on Drugs. A Catalyst Curriculum Guide
Creators: Rodríguez Gómez, Diana
di Castri, Theo
Publisher: name: Columbia University
Year: 2018
Subjects: Drug control
Drug control--Social aspects
Drugs--Social aspects
Education, Elementary
Education, Secondary

description: This curriculum guide aims at integrating the topic of drugs to K-12 classrooms from a Latin American and Caribbean social perspective. The guide provides information on what drugs are and do, but also on the socioeconomic implications between drugs and their use. In-class activities are provided to encourage high school students to think about these topics.