cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Scientific Advice in Europe provided by EMA and National Agencies
Creators: name: Laslop, Andrea
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Development costs of medicinal products are continuously increasing and have reached heights of one to two billion dollars for medicines containing new active substances and this is partly due to the high attrition rates in development programs. In order to mitigate this trend of ever increasing expenses,[for full text, please go to the a.m. URL]
description: 17. Jahreskongress für Klinische Pharmakologie
Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis and thrombolysis.
Creators: name: Wang, Xiaowei
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: Molecular imaging is a fast emerging technology allowing non-invasive detection of vascular pathologies. However, imaging modalities offering high resolution currently do not allow real-time imaging. We hypothesized that contrast enhanced ultrasound with microbubbles selectively targeted to activated platelets would offer high-resolution, real-time molecular imaging of evolving and dissolving arterial thrombi. Lipid-shell based gas-filled microbubbles (MB) were conjugated to either a single-chain antibody (scFv) specific for activated GPIIb/IIIa via binding to a Ligand-Induced Binding Site (LIBS-MB), or a non-specific scFv (control-MB). LIBS-MB, but not control-MB, strongly adhered to both immobilized activated platelets and micro-thrombi under flow. Thrombi, induced in carotid arteries of C57Bl6-mice in vivo by ferric chloride injury, were then assessed with ultrasound before and 20 minutes after MB injection, using grayscale area intensity measurement. Grayscale units converted to decibels demonstrated a significant increase after LIBS-MB but not after control-MB injection (p<0.001). Furthermore after thrombolysis with urokinase, LIBS-MB ultrasound-imaging allows monitoring of the reduction of thrombus size (p<0.001). A lower systematic dose of targeted fibrinolytic agent is required to achieve the same fibrinolytic potency. We demonstrate that GPIIb/IIIa-targeted microbubbles specifically bind to activated platelets in vitro and allow real-time molecular imaging of acute arterial thrombosis as well as monitoring of pharmacological thrombolysis in vivo. This non-invasive and cost effective imaging modality provides a unique approach to rapidly detect (micro)thrombi with high resolution, allowing for early diagnosis and therapy, as well as enabling the fast identification of success or failure of thrombolytic therapy.
Enhanced qubit readout using locally-generated squeezing and inbuilt Purcell-decay suppression
Creators: name: Govia, Luke C. G.
name: Clerk, Aashish A.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We introduce and analyze a dispersive qubit readout scheme where two-mode squeezing is generated directly in the measurement cavities. The resulting suppression of noise enables fast, high- fidelity readout of naturally weakly coupled qubits, and the possibility to protect strongly coupled qubits from decoherence by weakening their coupling. Unlike other approaches exploiting squeezing, our setup avoids the difficult task of transporting and injecting with high fidelity an externally-generated squeezed state. Our setup is also surprisingly robust against unwanted non-QND backaction effects, as interference naturally suppresses Purcell decay: the system acts as its own Purcell filter. Our setup is compatible with the experimental state-of-the-art in circuit QED systems, but the basic idea could also be realized in other systems.
description: 6 pages main text, 4 figures, 8 pages supplementary appendices
title: (R)evolution of early phase clinical trials in oncology
Creators: name: Mikus, Gerd
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Recruitment of patients in early phase clinical trials in oncology benefits from a large, stable, catchment population. Successful early phase clinical trials are based on close integration with the tumour site teams and multidisciplinary teams who provide treatment service. This enables the most cutting[for full text, please go to the a.m. URL]
description: 17. Jahreskongress für Klinische Pharmakologie
Supplementary Material for Beer, A.L., Becker, M., Frank, S.M., & Greenlee, M.W.: Vestibular and visual brain areas in the medial cortex of the human brain. Journal of Neurophysiology.
Creators: name: Beer, Anton
name: Becker, Markus
name: Frank, Sebastian
name: Greenlee, Mark
Publisher: name: figshare
Year: 2023
Subjects: Sensory systems

description: Supplementary Material for Beer, A.L., Becker, M., Frank, S.M., & Greenlee, M.W.: Vestibular and visual brain areas in the medial cortex of the human brain. Journal of Neurophysiology. The file includes Supplementary Figure S1 (brain areas in the lateral cortex), Supplementary Table S1 (size and coordinates of brain areas in the lateral cortex), Supplementary Table S2 (size and coordinates of subcortical brain regions), and Supplementary Figure S2 (brain areas in the medial cortex of individual brains). See the main text (article) in the Journal of Neurophysiology for further details.
Didácticas colaborativas y autorregulación del aprendizaje en tiempos de Ciencia Abierta
Creators: name: Vaca, Claudia
Publisher: name: Zenodo
Year: 2023
Subjects: Didácticas, rúbricas, autorregulación, autoevaluación, co evaluación, aprendizaje colaborativo

description: Conferencia para profesores de la Universidad Católica de Bolivia, en relación a las didácticas de aprendizaje colaborativo y autorregulación, rúbricas de auto y co evaluación, las ventajas de la ciencia abierta para estas didácticas colaborativas.
Additional file 1 of Effects of adding a diet intervention to exercise on hip osteoarthritis pain: protocol for the ECHO randomized controlled trial
Creators: name: Hall, Michelle
name: Hinman, Rana S.
name: Knox, Gabrielle
name: Spiers, Libby
name: Sumithran, Priya
name: Murphy, Nicholas J.
name: McManus, Fiona
name: Lamb, Karen E.
name: Cicuittini, Flavia
name: Hunter, David J.
name: Messier, Stephen P.
name: Bennell, Kim L.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1. ECHO study protocol version 2.
Synthesis and Performance Evaluation of Titanium Dioxide Supported Bentonite Composite for Methyl Orange Removal from Wastewater
Creators: name: Abrham, Balew
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2019

description: Dye effluents discharged from different industries causes series damage to aquatic animals as well as human beings by mutagenic and carcinogenic effects. Thus, the effluents needs to be treated before discharged to the environment using advanced oxidation process. TiO2 supported bentonite composite was used in the photocatalytic discoloration of dyes from wastewater i.e., methyl orange (MO). During usage of the composite as a photocatalyst for dye removal, physiochemical characteristics and effect of synthesis and photocatalytic parameters were investigated using Box-Behnkon Design response surface methodology. Characterization of the composite catalyst XRD analysis revealed that, the composite catalyst contains bentonite component (montmorillonite, quartz and feldspar) and TiO2 components (anatase and rutile). The crystal size of raw bentonite and composite were 24.73nm and 53.43nm respectively. In the design of experiment, the efficient catalyst was selected based on its dye removal efficiency via numerical optimization. Calcination temperature 400 C, calcination time 2h and TiO2 to bentonite ratio 0.2 were selected for 96.54% removal efficiency. Also for photocatalytic experiment dye concentration 10mg/L, catalyst dose 1.5g/L and UV irradiation time 2h gave 94.88% removal efficiency. The study justified that, composite photocatalyst titanium dioxide supported with bentonite has many advantages such as improve photocatalytic efficiency, recycling efficiency of the catalyst, improves the recovery rate, save the cost of treatment and improves the light absorption efficiency.
Probabilistic Condition Number Estimates For Real Polynomial Systems I: A Broader Family Of Distributions
Creators: name: Ergür, Alperen A.
name: Rojas, J. Maurice
name: Paouris, Grigoris
Publisher: name: arXiv
Year: 2016
Subjects: subject: Probability (math.PR)
subject: Algebraic Geometry (math.AG)
subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics

description: We consider the sensitivity of real roots of polynomial systems with respect to perturbations of the coefficients. In particular - for a version of the condition number defined by Cucker, Krick, Malajovich, and Wschebor - we establish new probabilistic estimates that allow a much broader family of measures than considered earlier. We also generalize further by allowing over-determined systems. Along the way, we derive new Lipshitz estimates for polynomial maps from R^n to R^m, extending earlier work of Kellog on the case m=1, which may be of independent interest. In Part II, we study smoothed complexity and how sparsity (in the sense of restricting which monomial terms can appear) can help further improve earlier condition number estimates.
description: We improved overall presentation of the paper and corrected a mistake that we spotted in the proof of Theorem 3.7. The correction had minimal effect on the proofs but changed the estimates in the main theorem
title: Die Denervierung der Fingergelenke: Grundlagen, Technik und klinische Ergebnisse
Creators: name: Ampofo, Christina
name: Konur, Wan
name: Haerle, Max
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: Denervierung
subject: Fingergelenk
subject: Arthrose
subject: 610 Medical sciences; Medicine

description: Fragestellung: Die Arthrose der Fingergelenke ist ein häufiges handchirurgisches Krankheitsbild. Die Denervierung, wie sie bei der Arthrose des Handgelenkes öfter durchgeführt wird, ist bei den Fingergelenken ein eher selten angewandtes Verfahren. Die zufriedenstellenden Ergebnisse dieser[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 56. Kongress der Deutschen Gesellschaft für Handchirurgie, 20. Jahrestagung der Deutschen Arbeitsgemeinschaft für Handtherapie (DAHTH)
title: Distraktionsverlängerung bei angeborenen Fehlbildungen der Hand
Creators: name: Mann, Max
name: Winkler, Frank
name: Hülsemann, Wiebke
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: Kallusdistraktion
subject: Fehlbildungen
subject: 610 Medical sciences; Medicine

description: Fragestellung: Bei angeborenen Fehlbildungen sind häufig einzelne Fingerstrahlen deutlich verkürzt. Um eine Greiffunktion aufzubauen oder zu verbessern ist eine Verlängerung Phalangen oder Metacarpalia hilfreich. Methodik: In den Jahren von 1994 bis 2014 haben wir bei 60 Patienten[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 56. Kongress der Deutschen Gesellschaft für Handchirurgie, 20. Jahrestagung der Deutschen Arbeitsgemeinschaft für Handtherapie (DAHTH)
Synthesis of Carboxymethyl Cellulose from Sugarcane Bagasse
Creators: name: Woldeamanuel, Yalew
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2011

description: Sugar cane bagasse is a potential cellulose source, though usually used as a fuel source for the boiler. This work reports concisely on a method to utilize sugar cane bagasse for preparing sodium carboxymethylcellulose (CMC) and its characteristics. The desirable characteristics that are imparted on the cellulose were the solubility, viscosity and others which are responsible for many applications. Furthermore, in this work the carboxymethylation reaction was optimized against the reaction temperature, reaction time, monochloroacetate concentration and sodium hydroxide concentration. The sugar cane bagasse is obtained shortly after the juice is extracted in the roller mill. Sodium hydroxide, chloroacetic acid and isopropanol were used for the carboxymethylation process. Firstly, the sugarcane bagasse was dried, ground to pass 1mm screen. Then the cellulose was extracted using 4N NaOH at 100oC for 1 hour. Finally, cellulose was converted to carboxymethyl cellulose (CMC) by basification and etherification processes using sodium monochloroacetate and sodium hydroxide. Two reactions were taken place simultaneously during carboxymethylation that were the primary reaction which produces pure carboxymethyl cellulose and side reaction that produce undesired sodium glycolate. The degree of substitution and viscosity were determined and then analyzed with respect to the reaction conditions using design expert statistical software. From the analysis the maximum degree of substitution was 1.92, and the maximum viscosity 25.4 cp. But after optimization of reaction conditions had been carried out, the optimized degree of substitution was 1.79 and viscosity 14.63cp. These were obtained at a reaction temperature of 30oC, reaction time of 2.95 hours, NaOH concentration of 25% w/v and chloroacetic acid concentration of 0.5 w/w. It is concluded that the sugarcane bagasse is a good source of cellulose that can be modified by etherification reaction to carboxymethylcellulose with a medium degree of substitution of about 1.79. Keywords: Degree of substitution, cellulose, carboxymethyl cellulose, sugar cane bagasse.
Developing a National Framework for Consumer Involvement in Cancer Control in Australia
Creators: name: Hanson, Susan
Publisher: name: La Trobe
Year: 2023

description: Submission note: For the Thesis Partial Fulfilment Doctor of Nursing (Research) Professional Doctorate (HDNR) to the School of Nursing and Midwifery, College of Science, Health and Engineering, La Trobe University, Victoria, Australia.

Despite consumer involvement in health and cancer control in Australia and internationally over several decades, the role of the consumer continues to reside at the margins of patient care and cancer control systems. With consumers now demanding more involvement in cancer control than has been historically afforded, this thesis offers a framework for guiding consumer involvement in cancer control in Australia with the expectation that it may improve outcomes for people affected by cancer. Thesis Aim This thesis aimed to describe the method and findings arising from the development of the National Framework for Consumer Involvement in Cancer Control in Australia. Project Design A three phased project design based on the principles of participatory research was adopted for the project. Quantitative and qualitative data were captured throughout the governance, consultation and development phases. Fifty-four organisations represented by seventy-five participants, consumers, health professionals, researchers and policy maker experts reached consensus on the framework and its constituent; elements, roles and model.2ResultsThis national framework for consumer involvement in cancer control in Australia offers systematic evidence-based guidance for consumers, health professionals, policy makers, researchers and organisations and includes:1. Four elements for guiding the development of consumer involvement in cancer control; i) committed organisations, ii)capable consumers; iii) inclusive groups; iv) shared focus.2. Five roles for guiding consumer involvement in cancer control at a patient, service and system level; i) personal engagement; ii)advocate; iii) advisor; iv) expert; v) partner.3. A model for the implementation of consumer involvement including; i) levels of participation on a hierarchy; ii) consumer capability; iii) organisational capacity. Conclusion The national framework for consumer involvement comprising elements, roles and a model for consumer involvement in cancer control, may offer the opportunity for more effective and meaningful consumer involvement. In addition, the framework allows for consumers to be respected, valued and legitimised in contributing towards improved outcomes. This proposed framework may guide evidence-based consumer involvement in cancer control for organisations, consumers, health professionals, policy makers, researchers with national and international applicability.
Sporormiella corynespora S. I. Ahmed & Cain 1972
Creators: name: Kruys, Åsa
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Pleosporales
Sporormiaceae
Sporormiella
Sporormiella corynespora

description: Sporormiella corynespora (Niessl) S.I. Ahmed & Cain (1972: 437).
 Habitat and distribution: —The new records were found on rabbit dung in the south of Sweden.
 Specimens examined: — SWEDEN. Blekinge: Åryd par., Björkeholmen, on rabbit dung after 1 month in moist chamber, Uppsala, 25 June 1963, Ingvar Nordin 1868u, F-529755 (UPS!); Skåne: Jonstorp par., Svanshall, on rabbit dung in moist chamber, Uppsala, 13 June 1963, Lena Junell 1664 n, F-529753 (UPS!).
 Taxonomic remarks: —A majority of the previous Swedish records of S. corynespora in Eriksson (2014) are transferred to P. octonalis.
description: Published as part of Kruys, Åsa, 2015, New species of Preussia with 8 - celled ascospores (Sporormiaceae, Pleosporales, Ascomycota), pp. 143-150 in Phytotaxa 234 (2) on page 145, DOI: 10.11646/phytotaxa.234.2.4, http://zenodo.org/record/13633064
Hennings, Emmy: Das Geheimnis des Eremiten oder die Engelsquelle/Das Geheimnis des Eremiten (2 Fassungen) / Hennings, Emmy: Das Geheimnis des Eremiten (2. Fassung)
Creators: name: Ball-Hennings, Emmy
Publisher: name: [s.n.]
Year: 2024

description: Dokument
title: Entwicklung eines Programms zur Routineimplementierung der Partizipativen Entscheidungsfindung in der Onkologie
Creators: name: Hahlweg, Pola
name: Müller, Evamaria
name: Hoffmann, Jana
name: Härter, Martin
name: Frosch, Dominick L
name: Elwyn, Glyn
name: Van Der Weijden, Trudy
name: Scholl, Isabelle
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Patientenzentrierung und partizipative Entscheidungsfindung (PEF) gewinnen im Gesundheitswesen zunehmend an Bedeutung. PEF bedeutet, dass der Patient und der Arzt aktiv und gleichberechtigt Informationen austauschen und die Behandlungsentscheidung gemeinsam treffen. PEF wird von vielen [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 14. Deutscher Kongress für Versorgungsforschung
Las consecuencias jurídicas de la fecundación artificial
Creators: name: Romero Rincón, Pedro
Publisher: name: Universidad de Cartagena
Year: 1984
Subjects: Inseminación artificial humana - Colombia
Inseminación artificial humana (Derecho civil) - Colombia

description: Tesis (Abogado) -- Universidad de Cartagena. Facultad de Derecho y Ciencias Políticas. Programa de Derecho, 1984
description: Historia dela fecundación artificial en Colombia, con referencia a la ética medica, posición de la iglesia católica, adulterio y derecho de familia, destacando que este procedimiento ha sido un progreso y un paso adelante de los científicos con el fin de contribuir a resolver problemas que aquejan a la sociedad.
title: Die Versorgungsrealität von Patienten mit einer Immunthrombozytopenie (ITP) in einer Schwerpunktpraxis für Hämatologie und Onkologie
Creators: name: Weide, Rudolf
name: Feiten, Stefan
name: Friesenhahn, Vera
name: Heymanns, Jochen
name: Kleboth, Kristina
name: Thomalla, Jörg
name: Van Roye, Christoph
name: Köppler, Hubert
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die Immunthrombozytopenie (ITP) ist eine Autoimmunerkrankung, die durch einen Mangel an Thrombozyten gekennzeichnet ist, was zu einer erhöhten Blutungsneigung führt. Neue Therapieoptionen wie Thrombopoietin-Rezeptor-Agonisten (TRA) und Rituximab haben Einzug in den klinischen [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 14. Deutscher Kongress für Versorgungsforschung
title: Fifteen years of drug development for patients with Multiple Sclerosis – adherence and compliance, what has been achieved?
Creators: name: Jahn, Sigbert
name: Hamburg, Helena
name: Pring-Åkerblom, Patricia
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Multiple Sclerosis (MS) is an autoimmune disease. The pathogenesis is mainly caused by a dys-regulated immune system contributing to the destruction of cellularstructures within the central nervous system (CNS) and therefore leading to the impairment of different body functions. After individually having[for full text, please go to the a.m. URL]
description: 17. Jahreskongress für Klinische Pharmakologie
Additional file 2 of Effects of adding a diet intervention to exercise on hip osteoarthritis pain: protocol for the ECHO randomized controlled trial
Creators: name: Hall, Michelle
name: Hinman, Rana S.
name: Knox, Gabrielle
name: Spiers, Libby
name: Sumithran, Priya
name: Murphy, Nicholas J.
name: McManus, Fiona
name: Lamb, Karen E.
name: Cicuittini, Flavia
name: Hunter, David J.
name: Messier, Stephen P.
name: Bennell, Kim L.
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 2. ECHO study participant consent form.
Preussia octomera Kruys
Creators: name: Kruys, Åsa
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Pleosporales
Sporormiaceae
Preussia
Preussia octomera

description: P. octomera (Auersw.) Kruys, in Kruys & Wedin (2009: 476).
 Habitat and distribution: —The new records are from fox and roe deer dung in Sweden.
 Specimens examined: — SWEDEN. Uppland: Läby par., Nåsten, in coniferous forest, on roe deer dung, 26August 1960, Nils Lundqvist 2800-b, F-529757 (UPS!); Södermanland: Åker par., Kvarnberga, on fox dung after 4 weeks in moist chamber, 26 May 1962, Ingvar Nordin 1211d, F-529754 (UPS!).
description: Published as part of Kruys, Åsa, 2015, New species of Preussia with 8 - celled ascospores (Sporormiaceae, Pleosporales, Ascomycota), pp. 143-150 in Phytotaxa 234 (2) on page 147, DOI: 10.11646/phytotaxa.234.2.4, http://zenodo.org/record/13633064
title: Pathophysiology and current medical therapy of open angle glaucoma
Creators: name: Kunert, Kathleen S.
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Open angle glaucoma (POAG) is a chronic progressive optic neuropathy associated with retinal ganglion cell and visual field loss. The goal of glaucoma therapy is to maintain the patients visual function and the related quality of life. The key risk factors for the development of glaucoma are higher [for full text, please go to the a.m. URL]
description: 17. Jahreskongress für Klinische Pharmakologie
Discrete mean square of the Riemann zeta-function over imaginary parts of its zeros
Creators: name: Garunkštis, Ramūnas
name: Laurinčikas, Antanas
Publisher: name: arXiv
Year: 2016
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics
subject: 11M26

description: Assume the Riemann hypothesis. On the right-hand side of the critical strip, we obtain an asymptotic formula for the discrete mean square of the Riemann zeta-function over imaginary parts of its zeros.
description: 18 pages
The molecular function of the Mixl1 transcription factor during early embryonic stem cell development
Creators: name: Wong, Michael Sebastian
Publisher: name: Monash University
Year: 2017
Subjects: Uncategorized

description: The Mixl1 gene encodes a homeodomain transcription factor that is required for normal mesoderm and endoderm development in the mouse. We have examined the consequences of enforced Mixl1 expression during mouse ESC differentiation. We found that in serum containing media differentiation to endoderm was promoted at the expense of ventral mesoderm. Luciferase reporter experiments indicate that Mixl1 can transactivate the Gsc, Sox17 and E-Cad promoters, supporting the hypothesis that Mixl1 has a direct role in definitive endoderm formation. To identify additional downstream transcriptional targets of Mixl1, we generated heterozygous Mixl1GFP/WT and homozygous null Mixl1GFP/Hygro ESCs. Candidate Mixl1 regulated genes with reduced expression in GFP+ cells isolated from differentiating Mixl1GFP/Hygro embryoid bodies included Pdgfrα and Flk1. Mixl1 bound to ATTA sequences located in Pdgfrα and Flk1 promoters in vivo. Mixl1 transactivated through these sequences in a DNA binding dependent manner. Using in vitro protein interactions studies Mixl1’s DNA-binding domain was shown to associate with T-box protein Brachyury. Gene expression and immunofluorescence analysis demonstrated overlapping expression of Mixl1 and the Brachyury during embryonic stem cell differentiation. Gel shift assays revealed that the Brachyury T-box domain could bind to Mixl1-DNA complexes. Furthermore, luciferase reporter experiments indicated that association with Mixl1 by Brachyury and related T-box factors inhibited the transactivation potential of Mixl1 on Gsc and Pdgfrα promoters. Taken together our results strengthen the position of Mixl1 as a key regulator of mesendoderm development during mammalian gastrulation.
title: Pharmakologische Behandlung der Altersdepression
Creators: name: Holthoff-Detto, Vjera
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Depression is the commonest and the most reversible mental disease in old age and is associated with physical illness, disability, life events and social isolation. Depression in old age carries an highly increased risk of suicide and also of natural mortality. Despite a favourable response to treatment,[for full text, please go to the a.m. URL]
description: 17. Jahreskongress für Klinische Pharmakologie
Estudio sanitario en la fábrica lechera "CODEGAN" calidad microbiológica y fisicoquímica de la leche
Creators: name: Pardo Carmona, Julia Ines
Publisher: name: Universidad de Cartagena
Year: 1986
Subjects: Leche - Análisis microbiológico
Leche - Análisis
Procesamiento de la leche

description: Tesis (Químico Farmacéutico).-- Universidad de Cartagena.Facultad Ciencias Farmacéuticas,1986
description: La presente investigación busca establecer las condiciones sanitarias de la fábrica Codegan, proceso, manipulación , conservación y su incidencia en la calidad microbiológica y fisicoquímica del producto terminado y envasado
title: Nadelfasziotomie und Hautrisse bei der schweren Dupuytren’schen Kontraktur
Creators: name: Lenze, Wolfgang
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: Nadelfasziotomie
subject: Hautrisse
subject: Minimal invasiv
subject: Dupuytren’sche Kontraktur
subject: 610 Medical sciences; Medicine

description: Fragestellung: Wenn die Haut in der Hohlhand oder in den Fingern unelastisch ist, z.B. durch Verwachsungen des Fibrosestrangs mit der Haut oder durch Vernarbungen nach vorangegangener partieller Fasziektomie, dann kann es bei der passiven Überstreckung der Finger zur Rissbildung kommen. Ist [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 56. Kongress der Deutschen Gesellschaft für Handchirurgie, 20. Jahrestagung der Deutschen Arbeitsgemeinschaft für Handtherapie (DAHTH)
Beyond communicative content: Slurs as (oppressive) speech acts
Creators: name: Cousens, Christopher
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Politics Media and Philosophy, School of Humanities and Social Sciences, College of Arts, Social Sciences, and Commerce, La Trobe University, Bundoora.
title: Diagnosefaktoren von Periimplantatinfektionen bei Knie- und Hüftendoprothesen (Eine retrospektive Analyse von 320 Fällen aus 12 Jahren)
Creators: name: Zajonz, Dirk
name: Wuthe, Lena
name: Prietzel, Torsten
name: Freiherr Von Salis-Soglio, Georg
name: Heyde, Christoph E.
name: Roth, Andreas
name: Josten, Christoph
name: Ghanem, Mohamed
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: Diagnostik
subject: TEP Infekt
subject: HTEP
subject: KTEP
subject: 610 Medical sciences; Medicine

description: Fragestellung: Die Implantationen von Hüft- (HTEP) und Kniegelenksendoprothesen (KTEP) gehören zu den häufigsten Operationen weltweit und aufgrund des demographischen Wandels mit deutlich steigender Tendenz. Dies führt jedoch ebenfalls zu einem ständigen Anstieg der Komplikationen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015)
Educación en emprendimiento y la cultura emprendedora de los estudiantes de las Facultades de Ciencias Económicas y de Economía y Negocios de la Universidad de Cartagena y la Universidad Tecnológica de Bolívar 2006-2015
Creators: name: Pérez Sáenz, Ricardo
Publisher: name: Universidad de Cartagena
Year: 2018
Subjects: Emprendimiento
Evaluación curricular

description: Tesis (Doctor en Ciencias de la Educación). -- Universidad de Cartagena - RUDECOLOMBIA. Doctorado en Ciencias de la Educación, 2018
description: Emprender, innovar y desarrollar la empresarialidad, son acciones estratégicas que un emprendedor realiza. Las capacidades humanas, la cultura emprendedora, el capital humano y emprendedor, son determinantes de la competencia para lograrlo. La educación en emprendimiento es un medio adecuado para desarrollar el ser, el saber y el hacer, que hace posible el surgimiento y la evolución del perfil ideal de un emprendedor, que fomente el mejoramiento de la calidad de vida y el bienestar de la sociedad. Las universidades son fundamentales para hacer posible la creación de empresas, el intraemprendimiento y la innovación que transforme la realidad del medio de influencia y de actuación de su comunidad institucional, debiendo desarrollar un marco estratégico, educativo, pedagógico, didáctico y curricular que articule la gestión académica, directiva, administrativa, financiera, investigativa y la de extensión, con el propósito de formar integralmente, seres creativos e inventivos, capaces de emprender e innovar e un ecosistema emprendedor dinámico y global. Precisamente, esta es la tesis que construimos, luego de preguntarnos si ¿La educación superior en emprendimiento impartida durante los años 2006 al 2015 en las Facultades de Ciencias Económicas de la Universidad de Cartagena y de Economía y Negocios de la Universidad Tecnológica de Bolívar, había logrado desarrollar cultura emprendedora en sus estudiantes, que potencialmente pueda contribuir a su desarrollo y bienestar e incidir en el contexto local? Y de implementar una investigación con enfoque mixto, de tipo descriptivo y explicativo, teniendo como informantes a 354 estudiantes, 356 egresados, 11 directivos, 9 académico – administrativos y a 212 docentes, contando con la participación de 5 expertos en educación para emprender y 2 emprendedores éxitos, que nos ayudaron a determinar el índice de capacidad emprendedora de los estudiantes de las dos facultades analizadas. Se concluye, que la motivación y la educación en emprendimiento que desarrollan las facultades, ha contribuido en la generación de ideas, la creación, puesta en marcha y mantenimiento de 213 empresas, en un 100% Pymes y 174 o el 81.69% de ellas, ubicadas en el sector servicios, proyectando, 146 del total de las empresas, entre 0 y 10 empleo cada una, mientras que 21 emprendedores, crearan entre 11 y 49 empleos nuevos, por empresa. Potencialmente, generarían un mínimo de 377 empleos y un máximo de 2.489, durante los próximos 3 años.
title: Ballonsakroplastie C-Bogen kontrolliert oder CT gesteuert?
Creators: name: Prokop, Axel
name: Chmielnicki, Marc
name: Andresen, Reimer
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: Sakruminsuffiziensfrakturen
subject: Sakroplastie
subject: 610 Medical sciences; Medicine

description: Fragestellung: Sakruminsuffizienzfrakturen werden häufig übersehen und führen zu starken therapierefraktären Schmerzen. Die Fraktur lässt sich am sensitivsten mit der MRT darstellen. Mit der Sakroplastie steht eine Methode zur Verfügung, die Brüche wie bei der Ballonkyphoplastie[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015)
title: Health Literacy bei pflegenden Angehörigen – Ergebnisse einer explorativen Analyse
Creators: name: Horn, Annett
name: Vogt, Dominique
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die häusliche Versorgung durch pflegende Angehörige wird angesichts der demografischen Entwicklung auch in den kommenden Jahren nicht an Bedeutung verlieren. Wie Forschungsbefunde belegen, sind pflegende Angehörige durch die Übernahme der Versorgung einer Vielzahl an[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 14. Deutscher Kongress für Versorgungsforschung
Transparency Material for Trusting and Working with Robots: A Relational Demography Theory of Preference for Robotic over Human Co-Workers
Creators: name: You, Sangseok
name: Robert, Lionel P.
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Management Information Systems
subject: Business
subject: Dissimilarity
subject: Swift Trust
subject: Human-Robot Interaction
subject: Co-worker
subject: Robot
subject: Relational Demography

description: Organizations are facing the new challenge of integrating humans and robots into one cohesive workforce. Relational demography theory (RDT) explains the impact of dissimilarities on when and why humans trust and prefer to work with others. This paper proposes that RDT would be a useful lens to help organizations understand how to integrate humans and robots into a cohesive workforce. We proposed a research model based on RDT and examined dissimilarities in gender, co-worker type (human vs. robot), and work style and personality. To empirically examine the research model, two experiments were conducted with 347 and 422 warehouse workers. Results show that the negative impacts of gender, work style, and personality dissimilarities on swift trust depended on the co-worker type. Gender dissimilarity had a stronger negative impact on swift trust in a robot co-worker, while work style and personality had a weaker negative impact on swift trust in a robot co-worker. Also, swift trust in a robot co-worker increased the preference for a robot co-worker over a human co-worker, while swift trust in a human co-worker decreased such preferences. Overall, this research contributes to our current understanding of human–robot collaboration by identifying the importance of dissimilarity from the perspective of RDT. The transparency materials include details about the methodology of the paper. NOTE: Transparency materials are not subject to peer review by MISQ. MISQ has reviewed: 1) That the minimum content is included in the transparency materials vis-à-vis the manuscript. 2) That the transparency materials are presented and organized in a high-quality manner (i.e., to a standard that readers of MIS Quarterly should expect).
title: Patientenzuzahlungen in der Zahnmedizin: Welchen Einfluss hat zuckerfreies Kaugummi auf Mundgesundheit und Kosten?
Creators: name: Spyra, Anna
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Karies ist die häufigste Zahnerkrankung in den Industrieländern. Die Ausgaben für die Behandlung der Karies lagen Schätzungen zufolge im Jahr 2012 in Deutschland bei ca. 6,3 Mrd. € für die GKV. Gleichzeitig ist ein rückläufiges Kariesrisiko erkennbar,[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 14. Deutscher Kongress für Versorgungsforschung
Additional file 1 of DrGA: cancer driver gene analysis in a simpler manner
Creators: name: Nguyen, Quang-Huy
name: Nguyen, Tin
name: Le, Duc-Hau
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Pharmacology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Plant Biology

description: Additional file 1: User manual. Tutorial and use examples of DrGA
Un invariante de matrices 2 x 2
Creators: name: Díaz Martínez, Roberto Carlos
Publisher: name: Universidad de Cartagena
Year: 2007
Subjects: Matrices (matemáticas)
Invariantes
Álgebra lineal - Estudios y ejercicios

description: Tesis (Matemático).--Universidad de Cartagena. Facultad de Ciencias Exactas y Naturales. Programa de Matemáticas, 2007
description: El espacio de las matrices puede ser considerado uno de los espacios mas fascinantes en el mundo matemático. La aspiración que se tiene en este trabajo es la de dar a conocer a un lector interesado, un resultado existente en las matrices cuadradas de orden 2 x 2, en el cual se involucran muchos conceptos de álgebra lineal y del álgebra abstracta.
title: Pathophysiology and current therapy of age-related macular degeneration (AMD)
Creators: name: Kunert, Kathleen S.
Publisher: name: German Medical Science GMS Publishing House
Year: 2015
Subjects: subject: 610 Medical sciences; Medicine

description: Age-related macular degeneration is a progressive disease of the central retina representing the leading cause of blindness in industrialized countries. Pathogenesis of AMD is multifactorial and not yet completely understood. Main risk factors are age, genetic predispositions and environmental determinants.[for full text, please go to the a.m. URL]
description: 17. Jahreskongress für Klinische Pharmakologie
Optimization of Extraction Process Parameters and Characterization of Gin Flavor from Juniper Berries (Juniperus Communis)
Creators: name: Tesfaye, Meroda
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2017

description: The aim of the thesis work was focused extraction, optimization and characterization of the essential oil from the berries of juniper to Gin flavor. A Juniper Berries of community family was the raw material of the experimental research which was collected from Chilimo forest 70 Km North West (NW) of Adiss Ababa. First, the juniper berries was dried through sun drying. Then the dried juniper berries were crushed in jaw crusher with sieve size and the samples were sieved using a set of sieves sizes arranged. Then after the experimental research activities were carried out by steam distillation set up. A general factorial design was employed to the extraction process using DESIGN EXPERT 7.0 software and linear regression model. This design helped to identify individual effects of extraction time, and particle size, as parameter. In the extraction experiment, the minimum oil yield of 0.487% was obtained at 2 hours and 1.4-2.5 mm and maximum oil yield of 2.27% was obtained 4 hours and 0.355 - 1mm. This shows that, increasing extraction time and decreasing particle size. Increases oil yield, The volatiles juniper berries essential oil in vapour form released from the berries were condensed and characterized their Physico - chemical properties of the berries oil studied for the optimum yield show that the oil is a solidifying oil at room temperature with having yellow colour,1.50 refractive index value, 2.25mpas dynamic viscosity, 170 boiling point, 0.8584g/cm3specificgravity,4.7 pH, 0.5 optical rotation ,1.4 ml/g acid value, 10.23ml/g iodine value, 47.69ml/g saponification value ,0.704% free fatty acid and 71.7 Brix. The chemical composition of essential oil extracted from Juniper berries using steam distillation was identified by GC-MS have α-pinene (73.12%), β‐myrcene (4.29%, β‐pinene (2.15 %), methylene (3.15%), phenylephrine (1.09%), and carene (4.74 %) and Evaluate sensory quality of Dry Gin liquor product. Therefore, particle size and extraction time have greater effect on the quality and quantity of juniper berries essential oil the findings of this study help to indicate the quality of the Juniper Berries oil which is important in the production of high value gin flavor. . Key Words: Juniper berries, Essential oil acceptability, Steam distillation, Extraction process, Gin Flavor.
Experience between past and present: natural history and antiquities in Britain, 1660–1820
Creators: name: Meikle, Lachlan
Publisher: name: La Trobe
Year: 2023

description: Submission note: This thesis is submitted in total fulfilment of the requirements for the degree of Doctor of Philosophyto the Department of History and Archaeology, School of Humanities and Social Sciences, College of Arts, Social Sciences and Commerce, La Trobe University, Victoria, Australia.
Preussia octonalis Solans
Creators: name: Kruys, Åsa
Publisher: name: Zenodo
Year: 2015
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Dothideomycetes
Pleosporales
Sporormiaceae
Preussia
Preussia octonalis

description: Preussia octonalis (S.I. Ahmed & Cain) Soláns, in Valldosera & Guarro (1990: 88).
 Habitat and distribution: —The new records are from Austria, Norway and Sweden. A majority of them are on old cow dung, but there are also single records on horse and sheep dung.
 Specimens examined: — AUSTRIA. Tyrol: on cow dung, September 1905. H. Rehm, F256928 (S!). NORWAY. Finnmark: Nord-Varanger par., Varanger peninsula, Vestre Jakobselv, on old sheep dung on the beach, developed in moist chamber, 28 July 1966, Nils Lundqvist 5004-m, F-171385 (UPS!); SWEDEN. Gotland: Östergarn par., Sysne, on the beach, on horse dung in moist chamber, Uppsala, 7 June 1959, Nils Lundqvist 2104-d, F-171379 (UPS!); Halland: Morup par., Morups tånge, on the beach, on cow dung after 25 days in moist chamber, 11 June 1960, Nils Lundqvist 2423c, F-171390 (UPS!); Härjedalen: Vemdalen par., 2 km N of Vemdalen at the bridge over river Veman, in coniferous forest, on old cow dung after 1 month in moist chamber, 15 June 1962, Nils Lundqvist 3397c, F-171380 (UPS!); Jämtland: Mörsil par., 4 km SE of Järpen in coniferous forest, on old cow dung after 4 weeks in moist chamber, 16 June 1962, Nils Lundqvist 3425j, F-171386 (UPS!); Lycksele Lappmark: Stensele par., 4 km SW of Skarvsjö, pasture, on old cow dung, 14 August 1960, Nils Lundqvist 2773b, F-171387 (UPS!); Södermanland: Strängnäs par., Tosterön Island, S of Knäppinge, in a meadow, on cow dung after 23 days in moist chamber, 14 June 1960, Nils Lundqvist 2454a, F-154023 (UPS!); Uppland: Söderby-Karl par., just N of Brölunda on a mountain, on cow dung after 1 month in moist chamber, 4 July 1960, Nils Lundqvist 2513e, F-171389 (UPS!); Ångermanland: Ytterlännäs par., Västertorp, in coniferous forest, on old cow dung after 4 weeks in moist chamber, 20 August 1961, Nils Lundqvist 3165d, F-171383 (UPS!); Åsele lappmark: Vilhelmina par., Meselefors, pasture, on old cow dung, 14 August 1960, Nils Lundqvist 2774a, F-171391 (UPS!); Öland: Bredsätra par., Kapelludden, pasture near the beach, on old cow dung after 21 days in moist chamber, 15 July 1960, Nils Lundqvist 2593k, F-171388 (UPS!); Öland: Ås par., 2 km N of the lighthouse, in a meadow at the beach, on old cow dung after 11 days in moist chamber, 13 July 1960, Nils Lundqvist 2568b, F-171381 (UPS!).
 Taxonomic remarks: —The new records of P. octonalis in Sweden have previously been reported as S. corynespora (Eriksson 2014).
description: Published as part of Kruys, Åsa, 2015, New species of Preussia with 8 - celled ascospores (Sporormiaceae, Pleosporales, Ascomycota), pp. 143-150 in Phytotaxa 234 (2) on page 147, DOI: 10.11646/phytotaxa.234.2.4, http://zenodo.org/record/13633064
Structural and functional characterisation of the zinc efflux transporter CzcD from Streptococcus pneumoniae
Creators: name: La Porta, Daniel
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Biochemistry and Genetics, School of Molecular Sciences, College of Science, Health and Engineering, La Trobe University, Bundoora.
Regulation of the Uridine Biosynthetic Pathway by the Bcl-2 Family Protein Bok
Creators: name: Srivastava, Rahul
Publisher: name: La Trobe
Year: 2023

description: Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, College of Science, Health and Engineering, La Trobe University, Victoria, Australia.
1 Brief, 2 Beilagen an Euer Wohlgebohren
Brief an [N.N.]
Creators: name: Naegeli, Hermann
Publisher: name: [s.n.]
Year: 1871

description: von Hermann Naegeli
description: Beilagen: Einige Berichtigungen und Ergänzungen zu der Hartmann'schen Biographie Hans Georg Naegeli's, in doppelter Ausführung mit geringen Abweichungen (Nr. 9 und 10)
Challenge of Exclusive Breast Feeding Among Female Nurses and Mid-Wives in Government and Private Hospitals of Addis Ababa, Ethiopia, 2015
Creators: name: Tafesse, Misrak
Publisher: name: National Academic Digital Repository of Ethiopia
Year: 2015

description: Background: Health care workers are important in the promotion, protection and support of breast feeding. Their ability to do this may be influenced by their knowledge, personal experiences and work. This study was to examine challenge of exclusive breast feeding among female nurses and mid-wives in government and private hospitals, Addis Ababa city. Objective: The main objective is to identify challenges for exclusive breast feeding among female nurses and mid-wives in selected government and private hospitals, Addis Ababa. Methodology: A hospital based cross-sectional study design used on a sample of 349 female nurses and mid-wives from April 13-May 11, 2015. Descriptive statistics and Bivariate and multivariate logistic regression were performed for possible association among variables. Odds ratios with 95% confidence interval were computed to determine the level of significance. Results: Exclusive breastfeeding among participant was found to be 23.5% being mid-wife (AOR=3.48 95% CI (1.22, 9.89), a women who gave birth through vaginal delivery AOR=0.289, 95%, CI (.09, 0.84) and resumption of work after 3 month (AOR=8.98 95% CI (4.00, 20.73) were independents associated with exclusive breastfeeding. Conclusion and recommendation: Though respondents had adequate knowledge on breast feeding, the practice of exclusive breastfeeding was low. Maternal profession, mode of delivery, the time before resuming work were factors associated with exclusive breast feeding. Appropriate education concerning breastfeeding, organizational support, directed at nurses and midwives is required to enhance EBF and duration of breastfeeding. Keywords: Exclusive breastfeeding, nurse and midwives, in Addis Ababa city