cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Assessing the Contribution of Hearing Loss in Prediction Models for Dementia Developed and Validated Using Data from the Canadian Longitudinal Study on Aging
Creators: name: Chan, Therese
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2023
Subjects: Dementia
Hearing loss
Prediction
Risk assessment
Modifiable risk factor
Prevention

description: Introduction: Hearing impairment is an emerging modifiable risk factor for dementia, but the relative predictive abilities of subjective and objective measures of hearing in dementia risk prediction algorithms are unclear. The objective was to develop and validate prediction models for 3-year incidence of dementia in older Canadians, and to evaluate the independent contribution of self-rated hearing impairment and audiometry-based moderate hearing loss. -- Methods: Baseline (2011 to 2015) and 3-year follow-up data from the Comprehensive cohort of the Canadian Longitudinal Study of Aging were used to build logistic regression models for 3-year incidence of dementia. Individuals who were under 55 years of age, reported physician-diagnosed dementia at baseline, and/or did not have data on dementia status at follow-up were excluded, producing a sample of 19,830 older Canadians. Hearing impairment was defined subjectively as self-reporting fair or poor hearing (versus excellent, very good, or good hearing) and was defined objectively as having a better-ear pure-tone average of the speech-frequencies (500, 1000, 2000, and 4000 Hz) above 40 dB with audiometry. -- Results: Both hearing measures were associated with dementia incidence after adjustment with other risk factors (self-rated fair/poor hearing adjusted odds ratio (aOR) 1.76, CI 0.96-3.23, audiometry-derived hearing loss aOR 2.60, CI 1.38-4.87). Audiometrically-derived hearing loss and self-rated hearing had similar population discrimination (c-statistic of model with self-rated hearing = 0.803, CI 0.752-0.859, c-statistic of model with audiometrically confirmed hearing loss = 0.808, CI 0.762-0.870) and similar calibration. -- Conclusion: Due to the accessibility of the self-reported hearing measure, the use of self-rated hearing in dementia risk prediction tools may have a larger clinical impact than audiometrically-defined hearing ability. Model performance within subgroups (e.g., older age groups, hypertension status, etc.) must be evaluated in future work to assess the magnitude of miscalibration, if any, in the use of self-reported hearing ability compared to audiometry.
Data stewardship and research data management tools for multimodal linking of imaging data in plasma medicine
Creators: name: Ahmadi, Mohsen
name: Wagner, Robert
name: Mattern, Philipp
name: Plathe, Nick
name: Bekeschus, Sander
name: Becker, Markus M.
name: Stöter, Torsten
name: Weidtkamp-Peters, Stefanie
Publisher: name: Zenodo
Year: 2023
Subjects: RDM
DSgG

description: A more detailed understanding of the effect of plasmas on biological systems can be fostered by combining data from different imaging modalities, such as optical imaging, fluorescence imaging, and mass spectrometry imaging. This, however, requires the implementation and use of sophisticated research data management (RDM) solutions to incorporate the influence of plasma parameters and treatment procedures as well as the effects of plasma on the treated targets. In order to address this, RDM activities on different levels and from different perspectives are started and brought together within the framework of the NFDI consortium NFDI4BIOIMAGE.
Der Landkreis Reutlingen (Kreisbeschreibungen des Landes Baden-Württemberg)
Creators: name: Lang, Peter Thaddäus
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Quellen zur Entstehung der Verfassung von Württemberg-Baden. Teil 2, bearbeitet v. Paul Sauer
Creators: name: Binder, Hans-Otto
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Orthosymplectic Lie superalgebras, Koszul duality, and a complete intersection analogue of the Eagon-Northcott complex
Creators: name: Sam, Steven V
Publisher: name: arXiv
Year: 2013
Subjects: subject: Commutative Algebra (math.AC)
subject: K-Theory and Homology (math.KT)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 13D02, 13C40, 17B10, 17B55, 18G10

description: We study the ideal of maximal minors in Littlewood varieties, a class of quadratic complete intersections in spaces of matrices. We give a geometric construction for a large class of modules, including all powers of this ideal, and show that they have a linear free resolution over the complete intersection and that their Koszul dual is an infinite-dimensional irreducible representation of the orthosymplectic Lie superalgebra. We calculate the algebra of cohomology operators acting on this free resolution. We prove analogous results for powers of the ideals of maximal minors in the variety of length 2 complexes when it is a complete intersection, and show that their Koszul dual is an infinite-dimensional irreducible representation of the general linear Lie superalgebra. This generalizes work of Akin, Józefiak, Pragacz, Weyman, and the author on resolutions of determinantal ideals in polynomial rings to the setting of complete intersections and provides a new connection between representations of classical Lie superalgebras and commutative algebra. As a curious application, we prove that the cohomology of a class of reducible homogeneous bundles on symplectic and orthogonal Grassmannians and 2-step flag varieties can be calculated by an analogue of the Borel-Weil-Bott theorem.
description: 35 pages; v2: updated references
Martin Biastoch, Tübinger Studenten im Kaiserreich
Creators: name: Bauer, Sonja-Maria
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
ENGINEERING GRAPHICS AND COMPUTERIZATION
Creators: name: Tosheva, Muhabbat
Publisher: name: Zenodo
Year: 2023

description: Engineering graphics, design important from the parts one is considered and computerization, these technologies, engineering in the field important tasks in execution help gives, for example, design and prototypes work release, presentations make up, and engineering protests more reliable and stored to doEngineering graphics and computerization, engineering in the field new technologies and new approaches in getting important place occupies They are education and teaching because it is important in the field they are new programs learning and them teaching for is used. This topic is new technologies learning, independent workers preparation and engineering in the field high to the results in reaching help gives
Enno Bünz, Stift Haug in Würzburg
Creators: name: Schmid, Alois
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
A Simultaneous Unobserved Components Analysis of US Output and the Great Moderation
Creators: name: Weber, Enzo
Publisher: name: Universität Regensburg
Year: 2009
Subjects: subject: Unobserved Components, Trend, Cycle, Identification, Great Moderation
subject: 330 Wirtschaft
subject: C32
subject: E32

description: In an unobserved components framework of US output trend and cycle, this paper seeks to determine the causal interaction between permanent and transitory innovations. For the purpose of identification, strategies of augmenting the cyclical dynamics as well as allowing for shifts in volatility are proposed. In the early 1980s, substantial predominance of cycle shocks gives way to strong negative spillovers of trend impulses, consistent with real business cycle theories. The coincident reduction of macroeconomic volatility mainly traces back to pronounced dampening of transitory disturbances. This ascribes an important role to the mitigation of policy interventions in explaining the Great Moderation.
Additional file 2 of Defining the concepts of a smart nursing home and its potential technology utilities that integrate medical services and are acceptable to stakeholders: a scoping review
Creators: name: Zhao, Yuanyuan
name: Rokhani, Fakhrul Zaman
name: Sazlina, Shariff-Ghazali
name: Devaraj, Navin Kumar
name: Su, Jing
name: Chew, Boon-How
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences
subject: Information Systems

description: Additional file 2. Search Strategy on Databases.
The Index of Dirac Operators on Incomplete Edge Spaces
Creators: name: Albin, Pierre
name: Gell-Redman, Jesse
Publisher: name: arXiv
Year: 2013
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We derive a formula for the index of a Dirac operator on a compact, even-dimensional incomplete edge space satisfying a "geometric Witt condition". We accomplish this by cutting off to a smooth manifold with boundary, applying the Atiyah-Patodi-Singer index theorem, and taking a limit. We deduce corollaries related to the existence of positive scalar curvature metrics on incomplete edge spaces.
900 Jahre Benediktinerabtei Marienberg 1096-1996
Creators: name: Ruf, Martin
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Ulrike Plate, Das ehemalige Benediktinerkloster St. Januarius in Murrhardt
Creators: name: Graf, Klaus
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Additional file 4 of Defining the concepts of a smart nursing home and its potential technology utilities that integrate medical services and are acceptable to stakeholders: a scoping review
Creators: name: Zhao, Yuanyuan
name: Rokhani, Fakhrul Zaman
name: Sazlina, Shariff-Ghazali
name: Devaraj, Navin Kumar
name: Su, Jing
name: Chew, Boon-How
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences
subject: Information Systems

description: Additional file 4. Code Sheet for Defining the Concepts and Criteria of a Smart Nursing Home.
A new research support service for ELNs using service engineering methods
Creators: name: Karsten, Adienne
Publisher: name: Zenodo
Year: 2023
Subjects: RDM
DSgG

description: This poster presents the implementation of the Electronic Laboratory Notebook (ELN) software, "elabFTW" at the University of Münster. lt provides an overview of the efficient design and optimization of the ELN implementation using the concept of service engineering while taking into account all stakeholders involved in a university setting.
A product formula for the eigenfunctions of a quartic oscillator
Creators: name: Hallnäs, Martin
name: Langmann, Edwin
Publisher: name: arXiv
Year: 2013
Subjects: subject: Mathematical Physics (math-ph)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: We consider the Schrödinger operator on the real line with an even quartic potential. Our main result is a product formula of the type $ψ_k(x)ψ_k(y) = \int_{\mathbb{R}} ψ_k(z)\mathcal{K}(x,y,z)dz$ for its eigenfunctions $ψ_k$. The kernel function $\mathcal{K}$ is given explicitly in terms of the Airy function $\mathrm{Ai}(x)$, and is positive for appropriate parameter values. As an application, we obtain a particular asymptotic expansion of the eigenfunctions $ψ_k$.
description: 18 pages. In v2 we added five references, reorganised some of the material and made some minor revisions and corrections; and in v3 we added references to work by T. T. Truong, who obtained a product formula for quartic oscillator eigenfunctions already in 1974
Additional file 5 of Defining the concepts of a smart nursing home and its potential technology utilities that integrate medical services and are acceptable to stakeholders: a scoping review
Creators: name: Zhao, Yuanyuan
name: Rokhani, Fakhrul Zaman
name: Sazlina, Shariff-Ghazali
name: Devaraj, Navin Kumar
name: Su, Jing
name: Chew, Boon-How
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences
subject: Information Systems

description: Additional file 5. The Code Sheet of Integration of Medical Services.
[ZeroPM prioritization workshop] Identifying potential pesticide dead-end transformation products of concern ZeroPM workshop 2024
Creators: name: Palm, Emma
name: Schymanski, Emma
Publisher: name: Zenodo
Year: 2024

description: This was presented at the ZeroPM workshop 2024 in Dessau as well as at IMSC 2024 in melbourne.

Please note that calculations were carried out using a beta version of BioTransformer4.0 and thus all numbers are preliminary.
Zur geistigen Welt der Franziskaner im 14. und 15. Jahrhundert. Die Bibliothek des Franziskanerklosters in Freiburg/Schweiz, hg. v. Ruedi Imbach u. Ernst Tremp ...
Creators: name: Neidiger, Bernhard
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Vanishing theorems for linearly obstructed divisors
Creators: name: Dumitrescu, Olivia
name: Postinghel, Elisa
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Geometry (math.AG)
subject: FOS: Mathematics
subject: 14C20 (Primary), 14J70, 14C17 (Secondary)

description: We study divisors in the blow-up of $\mathbb{P}^n$ at points in general position that are non-special with respect to the notion of linear speciality introduced in [5]. We describe the cohomology groups of their strict transforms via the blow-up of the space along their linear base locus. We extend the result to non-effective divisors that sit in a small region outside the effective cone. As an application, we describe linear systems of divisors in $\mathbb{P}^n$ blown-up at points in star configuration and their strict transforms via the blow-up of the linear base locus.
Additional file 6 of Defining the concepts of a smart nursing home and its potential technology utilities that integrate medical services and are acceptable to stakeholders: a scoping review
Creators: name: Zhao, Yuanyuan
name: Rokhani, Fakhrul Zaman
name: Sazlina, Shariff-Ghazali
name: Devaraj, Navin Kumar
name: Su, Jing
name: Chew, Boon-How
Publisher: name: figshare
Year: 2022
Subjects: subject: Artificial Intelligence and Image Processing
subject: FOS: Computer and information sciences
subject: Information Systems

description: Additional file 6. The Code Sheet of Stakeholders’ Acceptability.
СОЦИАЛЬНО-ФИЛОСОФСКИЕ АСПЕКТЫ ГЕНДЕРНОГО РАВЕНСТВА: ИСТОРИЯ И ПЕРСПЕКТИВЫ
Creators: name: Сайдалиева, Нигора
Publisher: name: Zenodo
Year: 2023

description: В данной статье рассматриваются социальные, философские, экономические аспекты гендерной проблемы. Проанализированы меры по решению гендерного равенства в Узбекистане. В статье говорится, что основа всех реформ в Узбекистане напрямую связана с вопросами гендерного равенства. Раскрыта роль и значение методологии исследования для обеспечения равенства женщин в Узбекистане. Рассмотрены вопросы улучшения социального положения женщин и укрепления их экономических прав при реализации государственных программ. Рассмотрен вопрос использования полного потенциала женщин во всех сферах жизни общества.
Helvetia Sacra, Abt. IV, Bd. 4: Die Antoniter, die Chorherren vom Heiligen Grab in Jerusalem und die Hospitaliter vom Heiligen Geist in der Schweiz, redigiert v. Eisanne Gilomen- Schenkel
Creators: name: Drossbach, Gisela
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
The accessibility of convex bodies and derandomization of the hit and run algorithm
Creators: name: Collins, Benoit
name: Kousha, Termeh
name: Kulik, Rafał
name: Szarek, Tomasz
name: Życzkowski, Karol
Publisher: name: arXiv
Year: 2013
Subjects: subject: Probability (math.PR)
subject: Mathematical Physics (math-ph)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: 65C40, 60J05, 81P40, 81P45

description: We introduce the concept of accessibility and prove that any convex body $X$ in $\mathbb R^d$ is accessible with relevant constants depending on $d$ only. This property leads to a new algorithm which may be considered as a natural derandomization of the hit and run algorithm applied to generate a sequence of random points covering $X$ uniformly. We prove stability of the Markov chain generated by the proposed algorithm and provide its rate of convergence.
description: revised version, new title and abstract; 13 pages, 2 figures
Additional file 1 of Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis
Creators: name: Suzuka, Takayasu
name: Kotani, Takuya
name: Saito, Takashi
name: Matsuda, Shogo
name: Sato, Takako
name: Takeuchi, Tohru
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Additional file 1. Experimental protocol. For induction of skin fibrosis, 8-week-old female Balb/c mice were subcutaneously injected with 100 μg/100 μL of bleomycin daily for 3 weeks. mASCs were administered 1 week after the start of bleomycin administration and evaluated at 3 weeks. mASCs: mouse adipose-derived mesenchymal stem cells.
Equivariant properties of symmetric products
Creators: name: Schwede, Stefan
Publisher: name: arXiv
Year: 2014
Subjects: subject: Algebraic Topology (math.AT)
subject: FOS: Mathematics
subject: 55P91

description: The filtration on the infinite symmetric product of spheres by the number of factors provides a sequence of spectra between the sphere spectrum and the integral Eilenberg-Mac Lane spectrum. This filtration has received a lot of attention and the subquotients are interesting stable homotopy types. While the symmetric product filtration has been a major focus of research since the 1980s, essentially nothing was known when one adds group actions into the picture. We investigate the equivariant stable homotopy types, for compact Lie groups, obtained from this filtration of infinite symmetric products of representation spheres. The situation differs from the non-equivariant case, for example the subquotients of the filtration are no longer rationally trivial and on the zeroth equivariant homotopy groups an interesting filtration of the augmentation ideals of the Burnside rings arises. Our method is by global homotopy theory, i.e., we study the simultaneous behavior for all compact Lie groups at once.
description: 33 pages
DataStew: Recommendations for Supporting Research through  Data Stewardship in Academic Research Institutions
Creators: name: Dierkes, Jens
name: Seidlmayer, Eva
name: Lindstädt, Birte
name: Förstner, Konrad
name: Hoffmann, Fabian
name: Depping, Ralf
Publisher: name: Zenodo
Year: 2023
Subjects: DSgG
RDM

description: A presentation about the results of the DataStew project, which analysed the status quo of data stewardship in Germany. The analysis had two main objectives: 1) to determine the current state of knowledge among the various stakeholders, and 2) to derive guidelines for policy and practice.
Additional file 2 of Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis
Creators: name: Suzuka, Takayasu
name: Kotani, Takuya
name: Saito, Takashi
name: Matsuda, Shogo
name: Sato, Takako
name: Takeuchi, Tohru
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Additional file 2. Experimental data. Genes of GREM-1 and IL-6 were not affected by hep-ASCs. For the skin mRNA expression levels of gremlin-1 (GREM-1), and interleukin (IL)-6 which may induce GREM-1, there was no significant difference between the groups. n = 7 in each group. Data are shown as mean ± SEM.
XALQARO OMMAVIY HUQUQ MUAMMOLARI: ZAMONAVIY HOLATI VA RIVOJLANISH ISTIQBOLLARI
Creators: name: Sabirova, Sabrina
Publisher: name: Zenodo
Year: 2023

description: Xalqaro ommaviy huquq davlatlar o'rtasidagi munosabatlarni tartibga soluvchi asos bo'lib xizmat qilib, tinchlik, hamkorlik va xalqlar o'rtasidagi o'zaro hurmat uchun ko'rsatmalar beradi. Biroq, hozirda, dunyo miqyosida xalqaro ommaviy huquq o'zining samaradorligi va dolzarbligiga salbiy ta'sir o'tkazuvchi turli xil muammolarga yuz tutmoqda.
Measurement of drug diffusivity in stratum corneum membranes and a polyacrylate matrix
Creators: name: Göpferich, Achim
name: Lee, Geoffrey
Publisher: name: Universität Regensburg
Year: 1991
Subjects: subject: STRATUM-CORNEUM; POLYMER MATRIX; DIFFUSION; MEASUREMENT
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: Diffusivities have been determined for the drug clenbuterol for three non-sink, diffusional problems: diffusion out of a polymer matrix, diffusion through excised, human stratum corneum, and the combined case of diffusion out of a polymer matrix through contiguous, excised stratum corneum. Numerical solution of the diffusion equation for these problems yeilds theoretical values of drug mass in the acceptor phase, m(a)(t)th, vs time. Diffusion was then measured experimentally and the best value for diffusivity obtained by comparing the values of drug mass in the acceptor phase, m(a)(t)exp, with the corresponding m(a)(t)th data. In this fashion it was possible to obtain diffusivities for diffusion out of the polymer matrix for various values of drug loading and matrix thickness. For the problem of diffusion through stratum corneum a value for the partition coefficient of clenbuterol as well as for its diffusivity could be determined. The two diffusivities obtained for the combined model (i.e., D(m) within the matrix and D(s) within the stratum corneum) agree quite well with those obtained for the two separate problems, but are more scattered. Partition coefficients could not be accurately determined for diffusion out of the matrix or the combined problem.
An improved diffusion/compartmental model for transdermal drug delivery from a matrix-type device
Creators: name: Göpferich, Achim
name: Lee, Geoffrey
Publisher: name: Universität Regensburg
Year: 1991
Subjects: subject: TRANSDERMAL DRUG DELIVERY; POLYMER MATRIX; MODEL
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: A mathematical model is presented for the description of transdermal drug delivery from a matrix-type delivery device. The model is partly diffusional and partly compartmental in nature. The matrix and stratum corneum are both considered to be diffusion layers, connected to a three-compartment model representing the viable epidermis/dermis, plasma, and peripheral tissues. The diffusion equation was solved numerically for the two diffusion layers under non-sink conditions. The ordinary differential equations for the compartmental model were also solved numerically. Combination of the two numerical solutions yielded a model which directly relates the properties of the matrix to the profile of drug mass in the plasma and the urinary excretion profile. The model was first used to analyse data obtained from an in vivo trial of a matrix-type transdermal delivery device for the drug clenbuterol. Fitting of the model to the profile of drug concentration in the plasma, the urinary excretion profile, and the mass of drug remaining in the matrix with a modified simplex method yielded values for the model constants. These compared very favourably with independent values taken from the literature. Simulations of the influences of drug diffusivity within the stratum corneum, drug loading in the matrix, matrix thickness and drug diffusivity within the matrix on the profile of drug concentration in the plasma were then made. The model is not restricted to a steady state nor does it specify particular drug release kinetics from the matrix. It does assume isotropic diffusion layers and spontaneous partitioning at boundaries.
Development and characterization of microencapsulated microspheres.
Creators: name: Göpferich, Achim
name: Alonso, Maria Jose
name: Langer, Robert S.
Publisher: name: Universität Regensburg
Year: 1994
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Delayed-Action Preparations
subject: Drug Compounding/methods
subject: Microscopy, Confocal
subject: Microscopy, Fluorescence
subject: Microspheres
subject: Polymers

description: A process for the coating of polymer microspheres with the same or different polymers and the characterization of these particles is described. Coated microspheres were manufactured from degradable and non-degradable polymers. Several physicochemical methods were used to establish that the particles were fully coated. Polarized light microscopy revealed strong birefringence of coated microspheres resulting in the appearance of Maltese Crosses on coated microspheres. After staining the core and the coating of particles using different fluorescent dyes, the uneven distribution of the dyes in the core and on the surface allows one to verify the coating success. After cutting microspheres using a cryomicrotome we were able to assess the microstructure of the coated microspheres. Electron Spectroscopy for Chemical Analysis (ESCA) was used to determine the surface composition of coated microspheres. Determining the carbon and oxygen content of samples we were able to verify the completeness of the coating procedure. To examine the benefit of coating microspheres, the effect of coating on the release of tetanus toxoid from polylactide microspheres was studied as a possible pharmaceutical application.
Ursula Creutz, Geschichte der ehemaligen Klöster im Bistum Berlin in Einzeldarstellungen
Creators: name: Matscha, Michael
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Additional file 3 of Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis
Creators: name: Suzuka, Takayasu
name: Kotani, Takuya
name: Saito, Takashi
name: Matsuda, Shogo
name: Sato, Takako
name: Takeuchi, Tohru
Publisher: name: figshare
Year: 2022
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Cancer

description: Additional file 3. Experimental data. Skin fibrosis reduced after administering mASCs. 1×105 mASCs administration significantly reduced dermal thickness (distance between epidermal–dermal junction and dermal–fat junction) and hydroxyproline content. n = 6 in each group. Data are presented as mean ± SEM. **P < 0.01. ***P < 0.005 vs. BLM-alone group.
Modeling of Polymer Erosion
Creators: name: Göpferich, Achim
name: Langer, Robert S.
Publisher: name: Universität Regensburg
Year: 1993
Subjects: subject: DRUG DELIVERY; RELEASE; POLYANHYDRIDES; KINETICS; MATRICES
subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin

description: The erosion of bioerodible polymers depends on many factors including the polymer chain length, bond cleavage velocity, swellability, crystallinity, and water diffusivity in the polymer matrix. This multitude of parameters makes modeling of erosion difficult. Only a few models exist that describe morphological changes of polymers during erosion qualitatively. In the present approach the polymer matrix was represented as the sum of small individual polymer matrix parts. The factors that determine erosion were combined, and the erosion of each matrix piece was regarded as a random event. Once such a matrix piece had come into contact with water, an individual life expectation was assigned to it using Monte Carlo techniques. The proposed model can describe complicated phenomena such as changes in polymer matrix microstructure, movement of erosion fronts, creation of pores, and weight loss during erosion, yet it is simple and easy to use. For quantitative evaluations the model was fit to experimental data for weight loss and erosion front movement. The so obtained model constants proved to be useful for the prediction of independent parameters like the porosity of polymer matrices during erosion. This modeling approach may help broaden the understanding of the role of polymer erosion when considering bioerodible polymers in applications such as controlled drug delivery or tissue engineering.
Additional file 1 of High prevalence of Pfcrt 76T and Pfmdr1 N86 genotypes in malaria infected patients attending health facilities in East Shewa zone, Oromia Regional State, Ethiopia
Creators: name: Hassen, Jifar
name: Alemayehu, Gezahegn Solomon
name: Dinka, Hunduma
name: Golassa, Lemu
Publisher: name: figshare
Year: 2022
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology
subject: Computational Biology

description: Additional file 1. Primers sequences used in nested PCR for the amplification of Pfcrt and Pfmdr1 genes.
Thermodynamic partition function from quantum theory for black hole horizons in loop quantum gravity
Creators: name: Majhi, Abhishek
Publisher: name: arXiv
Year: 2013
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We establish the link between the thermodynamics and the quantum theory of black hole horizons through the construction of the thermodynamic partition function, partly based on some physically plausible arguments, by beginning from the description of quantum states of the horizon, considering loop quantum gravity(LQG) as the underlying theory. Although, the effective `thermalized\rq{} form of the partition function has been previously used in the literature to study the effect of thermal fluctuations of the black hole horizon, nonetheless the direct link to any existing quantum theory (which is here taken to be LQG), especially a derivation of the partition function from the quantum states of the horizon, appears to be hitherto absent. This work is an attempt to bridge this small, but essential, gap that appears to be present between the existing literature of quantum theory and thermodynamics of black holes. Further, it may be emphasized that this work is {\it only} concerned with the {\it metric independent} approaches to black hole thermodynamics.
description: title changed and modifications made to match the published version
Deep $Π^0_1$ Classes
Creators: name: Bienvenu, Laurent
name: Porter, Christopher P.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Logic (math.LO)
subject: FOS: Mathematics
subject: F.1.1; F.4.1
subject: 03D32, 68Q30

description: A set of infinite binary sequences $\mathcal{C}\subseteq2^ω$ is negligible if there is no partial probabilistic algorithm that produces an element of this set with positive probability. The study of negligibility is of particular interest in the context of $Π^0_1$ classes. In this paper, we introduce the notion of depth for $Π^0_1$ classes, which is a stronger form of negligibility. Whereas a negligible $Π^0_1$ class $\mathcal{C}$ has the property that one cannot probabilistically compute a member of $\mathcal{C}$ with positive probability, a deep $Π^0_1$ class $\mathcal{C}$ has the property that one cannot probabilistically compute an initial segment of a member of $\mathcal{C}$ with high probability. That is, the probability of computing a length $n$ initial segment of a deep $Π^0_1$ class converges to 0 effectively in $n$. We prove a number of basic results about depth, negligibility, and a variant of negligibility that we call $\mathit{tt}$-negligibility. We also provide a number of examples of deep $Π^0_1$ classes that occur naturally in computability theory and algorithmic randomness. We also study deep classes in the context of mass problems, we examine the relationship between deep classes and certain lowness notions in algorithmic randomness, and establish a relationship between members of deep classes and the amount of mutual information with Chaitin's $Ω$.
An infinite-dimensional approach to path-dependent Kolmogorov equations
Creators: name: Flandoli, Franco
name: Zanco, Giovanni
Publisher: name: arXiv
Year: 2013
Subjects: subject: Probability (math.PR)
subject: FOS: Mathematics

description: In this paper, a Banach space framework is introduced in order to deal with finite-dimensional path-dependent stochastic differential equations. A version of Kolmogorov backward equation is formulated and solved both in the space of $L^p$ paths and in the space of continuous paths using the associated stochastic differential equation, thus establishing a relation between path-dependent SDEs and PDEs in analogy with the classical case. Finally, it is shown how to establish a connection between such Kolmogorov equation and the analogue finite-dimensional equation that can be formulated in terms of the path-dependent derivatives recently introduced by Dupire, Cont and Fournié.
description: Published at http://dx.doi.org/10.1214/15-AOP1031 in the Annals of Probability (http://www.imstat.org/aop/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Additional file 1 of Factors influencing consumption of traditional diets: stakeholder views regarding sago consumption among the indigenous peoples of West Papua
Creators: name: Sidiq, Fathir Fajar
name: Coles, David
name: Hubbard, Carmen
name: Clark, Beth
name: Frewer, Lynn J.
Publisher: name: figshare
Year: 2022
Subjects: subject: Sociology
subject: FOS: Sociology

description: Additional file 1. COREQ checklist.
Antonia Leugers, Gegen eine Mauer bischöflichen Schweigens
Creators: name: Sauer, Thomas
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Information Content of Systems as a Physical Principle
Creators: name: Czekaj, L.
name: Horodecki, M.
name: Horodecki, P.
name: Horodecki, R.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Quantum Physics (quant-ph)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: To explain conceptual gap between classical/quantum and other, hypothetical descriptions of world, several principles has been proposed. So far, all these principles have not explicitly included the uncertainty relation. Here we introduce an information content principle (ICP) which represents the new - constrained uncertainty principle. The principle, by taking into account the encoding/decoding properties of single physical system, is capable of separation both classicality and quanta from a number of potential physical theories including hidden variable theories. The ICP, which is satisfied by both classical and quantum theory, states that the amount of non-redundant information which may be extracted from a given system is bounded by a perfectly decodable information content of the system. We show that ICP allows to discriminate theories which do not allow for correlations stronger than Tsirelson's bound. We show also how to apply the principle to composite systems, ruling out some theories despite their elementary constituents behave quantumly.
description: 5 pages + 5 pages of appendix, 4 figures, version accepted in Phys. Rev. A
title: Broadband and Student Performance Gaps After the COVID-19 Pandemic
Creators: name: Hampton, Keith N.
name: Hales, G.E.
name: Bauer, Johannes M.
Publisher: name: James H. and Mary B. Quello Center, Michigan State University
Year: 2023

description: The COVID-19 pandemic rapidly changed how Americans viewed the importance of broadband Internet connectivity. In a short period of time, a national emergency shifted how and where people accessed work and education, how they interacted with friends and family, and how they spent their time. An inadequate infrastructure for broadband access left rural Americans and particularly rural youth at higher risk. This study was designed to assess the impact of the COVID-19 pandemic on home Internet connectivity, student achievement, and adolescent well-being. This report builds on the findings of a study on Broadband and Student Performance Gaps released in the weeks before the start of the COVID-19 pandemic. That report highlighted the low levels of broadband access by rural Michigan students and the detrimental impact from a lack of access on their academic performance, educational aspirations, career choices, and general well-being. In 2022, we returned to the same schools that we first surveyed in 2019. We asked students about their experience with Internet technologies and with learning from home during the pandemic. Our findings paint a picture of how rural school districts and other stakeholders rapidly mobilized to address a national crisis. In a remarkably short period of time, schools accessed state and federal resources to close gaps in rural Internet access and computing devices. Over the COVID-19 pandemic, students with better home Internet access experienced fewer problems learning from home. Learning from home boosted students’ competencies with digital technologies. It also helped insulate some students from a broad pandemic decline in career interests related to science, technology, math, and engineering (STEM).  Learning from home did not, however, protect students from a large drop in intention to pursue post-secondary education at a college or university. Although students reported exceptionally high feelings of isolation during the pandemic, these feelings have rapidly diminished. We found no substantive difference in young people’s self-esteem in comparison to before the pandemic. Young people are now spending more time in person with their friends than they did in the years before the pandemic. As youth leisure activities shifted, we also found that those young people, who spend more time using a variety of media, especially social media, are spending the most time in person with friends.
Study of the in vitro penetration of the topical glucocorticoid betamethasone-17-valerate from solution-type gels into a multilayer membrane system.
Creators: name: Bendas, Barbara
name: Göpferich, Achim
name: Lee, Geoffrey
name: Neubert, R.
Publisher: name: Universität Regensburg
Year: 1993
Subjects: subject: 570 Biowissenschaften, Biologie
subject: 610 Medizin
subject: Betamethasone 17-Valerate/chemistry
subject: Chemistry, Physical
subject: Gels
subject: Membranes, Artificial
subject: Physicochemical Phenomena
subject: Solutions

description: The in vitro transport of betamethasone-17-valerate (1) into a multilayer membrane system has been investigated. Subsaturated formulations of 1 were studied as formed by mixing appropriate propylene glycol/water cosolvent systems. The AUC (drug concentration in acce ptor membrane as a function of time) and the diffusivity of the drug in the vehicle were used to evaluate the results of the in vitro transport. The importance and relationship between solubility, partition coefficient, and diffusivity for the process of in vitro penetration of 1 are discussed.
Klemens-August Recker, »Wem wollt ihr glauben?« Bischof Berning im Dritten Reich
Creators: name: Feldkamp, Michael F.
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Antonius Liedhegeneri, Christentum und Urbanisierung
Creators: name: Schmiedl, Joachim
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Corporate hedging and capital structure decistion - towards an integrated framework for value creation
Creators: name: Hahnenstein, Lutz
name: Röder, Klaus
Publisher: name: Universität Regensburg
Year: 2006
Subjects: subject: 330 Wirtschaft

description: We suggest a joint optimization model for a firm’s hedging and leverage decisions that helps to establish an integrated framework for value creation. Rather than artificially separating the two interrelated parts of the firm’s financial policy, we treat both corporate decision variables as endogenous. We argue that exogenous differences between financial distress costs across firms, and particularly across industries, simultaneously influence corporate risk management and capital structure decisions. Using anecdotal evidence, our focus is not on socalled direct bankruptcy costs, but rather on the cross-sectional variation in indirect bankruptcy costs, which may result from a deterioration of relationships with customers, suppliers, or other stakeholders prior to the legal act of bankruptcy.
Small-time asymptotics for a general local-stochastic volatility model with a jump-to-default: curvature and the heat kernel expansion
Creators: name: Armstrong, John
name: Forde, Martin
name: Lorig, Matthew
name: Zhang, Hongzhong
Publisher: name: arXiv
Year: 2013
Subjects: subject: Pricing of Securities (q-fin.PR)
subject: FOS: Economics and business

description: We compute a sharp small-time estimate for implied volatility under a general uncorrelated local-stochastic volatility model. For this we use the Bellaiche \cite{Bel81} heat kernel expansion combined with Laplace's method to integrate over the volatility variable on a compact set, and (after a gauge transformation) we use the Davies \cite{Dav88} upper bound for the heat kernel on a manifold with bounded Ricci curvature to deal with the tail integrals. If the correlation $ρ< 0$, our approach still works if the drift of the volatility takes a specific functional form and there is no local volatility component, and our results include the SABR model for $β=1, ρ\le 0$. \bl{For uncorrelated stochastic volatility models, our results also include a SABR-type model with $β=1$ and an affine mean-reverting drift, and the exponential Ornstein-Uhlenbeck model.} We later augment the model with a single jump-to-default with intensity $\lm$, which produces qualitatively different behaviour for the short-maturity smile; in particular, for $ρ=0$, log-moneyness $x > 0$, the implied volatility increases by $\lm f(x) t +o(t) $ for some function $f(x)$ which blows up as $x \searrow 0$. Finally, we compare our result with the general asymptotic expansion in Lorig, Pagliarani \& Pascucci \cite{LPP15}, and we verify our results numerically for the SABR model using Monte Carlo simulation and the exact closed-form solution given in Antonov \& Spector \cite{AS12} for the case $ρ=0$.
description: 27 pages, 2 figures
Klaus Keller, Die Liturgie der Eheschließung in der katholischen Aufklärung
Creators: name: Reifenberg, Hermann
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Dominik Burkard, »Oase in einer aufklärungssüchtigen Zeit«?
Creators: name: Hammerstein, Notker
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Hexenverfolgung. Beiträge zur Forschung, hg. v. Sänke Lorenz u. Dieter R. Bauer ...
Creators: name: Becker, Thomas P.
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Der Mainzer Kurfürst als Reichserzkanzler, hg. v. Peter Claus Hartmann
Creators: name: Ochs, Andreas
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Helmut Neuhaus, Das Reich in der Frühen Neuzeit
Creators: name: Wolf, Hubert
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Die Hauptinstruktionen Gregors XV. 1621-1623, bearb. v. Klaus Jaitner
Creators: name: Feldkamp, Michael F.
Publisher: name: Rottenburger Jahrbuch für Kirchengeschichte
Year: 1970

description: Rottenburger Jahrbuch für Kirchengeschichte, Bd. 18 (1999): Rottenburger Jahrbuch für Kirchengeschichte, Band 18
Dense graph limits under respondent-driven sampling
Creators: name: Athreya, Siva
name: Röllin, Adrian
Publisher: name: arXiv
Year: 2013
Subjects: subject: Probability (math.PR)
subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We consider certain respondent-driven sampling procedures on dense graphs. We show that if the sequence of the vertex-sets is ergodic then the limiting graph can be expressed in terms of the original dense graph via a transformation related to the invariant measure of the ergodic sequence. For specific sampling procedures, we describe the transformation explicitly.
description: Published at http://dx.doi.org/10.1214/15-AAP1144 in the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Queen polymorphism in the North American harvester ant, Ephebomyrmex imberbiculus
Creators: name: Heinze, Jürgen
name: Hölldobler, B.
name: Cover, S. P.
Publisher: name: Universität Regensburg
Year: 1992
Subjects: subject: EPHEBOMYRMEX; POGONOMYRMEX; HARVESTER ANTS; WING REDUCTION; QUEEN POLYMORPHISM
subject: 570 Biowissenschaften, Biologie
subject: 590 Tiere (Zoologie)

description: In the North American harvester ant Ephebomyrmex imberbiculus, in addition to dealate queens, wingless female reproductives occur that have greatly reduced ocelli and thoracic sutures (intermorphic queens). Both queen types are equivalent in function, and do not differ in ovarian morphology. Colonies may contain several inseminated and egg-laying intermorphic queens. We discuss queen polymorphism in respect to the biology of this desert-dwelling species.