cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A phase I/II study of intrathecal idursulfase-IT in children with severe mucopolysaccharidosis II
Creators: name: Muenzer, Joseph
name: Hendriksz, Christian J.
name: Perry, Victor
name: Solanki, Guirish A.
name: Fan, Zheng
name: Pan, Luying
name: Mascelli, Mary Ann
name: Santra, Saikat
name: Vijayaraghavan, Suresh
name: Barbier, Ann J.
name: Wang, Nan
name: Sciarappa, Kenneth
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Approximately two-thirds of patients with the lysosomal storage disease mucopolysaccharidosis II have progressive cognitive impairment. Intravenous (i.v.) enzyme replacement therapy does not affect cognitive impairment because recombinant iduronate-2-sulfatase (idursulfase) does not penetrate the blood-brain barrier at therapeutic concentrations. We examined the safety of idursulfase formulated for intrathecal administration (idursulfase-IT) via intrathecal drug delivery device (IDDD). A secondary endpoint was change in concentration of glycosaminoglycans in cerebrospinal fluid. Sixteen cognitively impaired males with mucopolysaccharidosis II who were previously treated with weekly i.v. idursulfase 0.5 mg/kg for ≥6 months were enrolled. Patients were randomized to no treatment or 10-mg, 30-mg, or 1-mg idursulfase-IT monthly for 6 months (four patients per group) while continuing i.v. idursulfase weekly. No serious adverse events related to idursulfase-IT were observed. Surgical revision/removal of the IDDD was required in 6 of 12 patients. Twelve total doses were administrated by lumbar puncture. Mean cerebrospinal fluid glycosaminoglycan concentration was reduced by approximately 90% in the 10-mg and 30-mg groups and approximately 80% in the 1-mg group after 6 months. These preliminary data support further development of investigational idursulfase-IT in MPS II patients with the severe phenotype who have progressed only to a mild-to-moderate level of cognitive impairment.Genet Med advance online publication 02 April 2015Genetics in Medicine (2015); doi:10.1038/gim.2015.36.
Learning-based Compressive Subsampling
Creators: name: Baldassarre, Luca
name: Li, Yen-Huan
name: Scarlett, Jonathan
name: Gözcü, Baran
name: Bogunovic, Ilija
name: Cevher, Volkan
Publisher: name: arXiv
Year: 2015
Subjects: subject: Information Theory (cs.IT)
subject: Machine Learning (cs.LG)
subject: Machine Learning (stat.ML)
subject: FOS: Computer and information sciences

description: The problem of recovering a structured signal $\mathbf{x} \in \mathbb{C}^p$ from a set of dimensionality-reduced linear measurements $\mathbf{b} = \mathbf {A}\mathbf {x}$ arises in a variety of applications, such as medical imaging, spectroscopy, Fourier optics, and computerized tomography. Due to computational and storage complexity or physical constraints imposed by the problem, the measurement matrix $\mathbf{A} \in \mathbb{C}^{n \times p}$ is often of the form $\mathbf{A} = \mathbf{P}_Ω\boldsymbolΨ$ for some orthonormal basis matrix $\boldsymbolΨ\in \mathbb{C}^{p \times p}$ and subsampling operator $\mathbf{P}_Ω: \mathbb{C}^{p} \rightarrow \mathbb{C}^{n}$ that selects the rows indexed by $Ω$. This raises the fundamental question of how best to choose the index set $Ω$ in order to optimize the recovery performance. Previous approaches to addressing this question rely on non-uniform \emph{random} subsampling using application-specific knowledge of the structure of $\mathbf{x}$. In this paper, we instead take a principled learning-based approach in which a \emph{fixed} index set is chosen based on a set of training signals $\mathbf{x}_1,\dotsc,\mathbf{x}_m$. We formulate combinatorial optimization problems seeking to maximize the energy captured in these signals in an average-case or worst-case sense, and we show that these can be efficiently solved either exactly or approximately via the identification of modularity and submodularity structures. We provide both deterministic and statistical theoretical guarantees showing how the resulting measurement matrices perform on signals differing from the training signals, and we provide numerical examples showing our approach to be effective on a variety of data sets.
description: Submitted to IEEE Journal on Selected Topics in Signal Processing
title: Postoperative Makulaödeme
Creators: name: Wolfensberger, Thomas
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: 610 Medical sciences; Medicine

description: Seit seiner Erstbeschreibung vor über 60 Jahren kann das postoperative Makulaödem vor allem nach Kataraktoperation in ca 0.5-2 % der Fälle nachgewiesen werden. Das post-operative Makulaödem kann sich jedoch potenziell nach jedem intraokularen Eingriff manifestieren. Pathophysiologisch[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2018
Sonnenfleckenzeichnung Nr. 278.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.12.1984, 10:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Viral assoziierte anteriore Uveitis
Creators: name: Pleyer, Uwe
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: 610 Medical sciences; Medicine

description: Intraokulare virale Infektionen nehmen zu. Dies betrifft einerseits das große Spektrum der Uveitis durch Viren v.a. der Herpesgruppe (Herpes simplex 1,2-, Varizella Zoster-Cytomegalo-, und Epstein-Barr-Virus) sowie Rubella Virus-assoziierte Krankheitsbilder („Fuchs Uveitis“). Andererseits[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2018
A semiquantitative metric for evaluating clinical actionability of incidental or secondary findings from genome-scale sequencing
Creators: name: Weck, Karen E.
name: Wilhelmsen, Kirk C.
name: Strande, Natasha T.
name: O'Daniel, Julianne M.
name: Jensen, Brian C.
name: Juengst, Eric T.
name: Berg, Jonathan S.
name: Roche, Myra I.
name: Evans, James P.
name: Crooks, Kristy R.
name: Booker, Jessica K.
name: Powell, Bradford C.
name: Powell, Cynthia M.
name: Lee, Kristy
name: Nelson, Daniel K.
name: Foreman, Ann Katherine M.
name: Boshe, Lacey
name: Skrzynia, Cecile
name: Carey, Timothy
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: As genome-scale sequencing is increasingly applied in clinical scenarios, a wide variety of genomic findings will be discovered as secondary or incidental findings, and there is debate about how they should be handled. The clinical actionability of such findings varies, necessitating standardized frameworks for a priori decision making about their analysis.
A Survey on Behavioral Models of Intra-Household Consumption.
Creators: name: Hajebi, Elnaz
name: Ahmadi Shadmehri, Mohammad Taher
name: Peykarjou, Kambiz
name: Sotoudehnia, Salman
Publisher: name: figshare
Year: 2022
Subjects: Economics

description: In the theory of microeconomics, in discussions related to consumer behavior, it is usually assumed that the household acts as a decision-making unit like an
 individual, and for a household, a budget constraint and a utility function are considered. As a result, only the general behavior of the household will be observable and analyzed. Since the 1980s, this method, which is called the Unitary Household Model, has been criticized theoretically and empirically, and issues such as the inequality of household members have been raised. In contrast to the Unitary Household model, Collective Household Model was proposed in consumer behavior. According to this method, in multi-member households,
 each member has their own preferences, and what can be important between these members is the intra-household bargaining process. In this article, at first, we will give an introduction including the theoretical foundation and the
 background of the research, then, while introducing the unitary model as an introduction to collective models, we will examine the collective model and intahousehold collective models. At the end, the contents are summarized and suggestions for future research are presented.
title: Antivirale Therapie und Diagnostik von Herpesviren – Neue Entwicklungen aus der Sicht der Virologie
Creators: name: Stein, Angela
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: 610 Medical sciences; Medicine

description: Seit vielen Jahren sind Aciclovir und weitere DNA-Polymerase-Inhibitoren erfolgreich gegen Herpes simplex und Varizella zoster im Einsatz. Da zunehmend Resistenzen gegen diese Wirkstoffe auftreten, werden Alternativen bedeutsam. Aktuelle Entwicklungen zeigen, dass mit den richtigen molekularen Zielgruppen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2018
Al4SiC4 würtzite crystal: structural, optoelectronic, elastic and piezoelectric properties
Creators: name: Pedesseau, L.
name: Even, J.
name: Modreanu, M.
name: Chaussende, D.
name: Chaix-Pluchery, O.
name: Durand, O.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: New experimental results supported by theoretical analyses are proposed for aluminum silicon carbide (Al4SiC4). A state of the art implementation of the Density Functional Theory is used to analyze the experimental crystal structure, the Born charges, the elastic and piezoelectric properties. The Born charge tensor is correlated to the local bonding environment for each atom. The electronic band structure is computed including self-consistent many-body corrections. Al4SiC4 material properties are compared to other wide band gap Würtzite materials. From a comparison between an ellipsometry study of the optical properties and theoretical results, we conclude that the Al4SiC4 material has indirect and direct band gap energies of about 2.5eV and 3.2 eV respectively.
description: 10 pages, 4 figures
Sonnenfleckenzeichnung Nr. 206.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 27.08.1984, 07:45, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Rational approximation of affine coordinate subspaces of Euclidean space
Creators: name: Ramírez, Felipe A.
name: Simmons, David S.
name: Süess, Fabian
Publisher: name: arXiv
Year: 2015
Subjects: subject: Number Theory (math.NT)
subject: FOS: Mathematics

description: We show that affine coordinate subspaces of dimension at least two in Euclidean space are of Khintchine type for divergence. For affine coordinate subspaces of dimension one, we prove a result which depends on the dual Diophantine type of the basepoint of the subspace. These results provide evidence for the conjecture that all affine subspaces of Euclidean space are of Khintchine type for divergence.
description: 10 pages. v2: new introduction
Sonnenfleckenzeichnung Nr. 251.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.10.1984, 08:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Bayesian modeling of networks in complex business intelligence problems
Creators: name: Durante, Daniele
name: Paganin, Sally
name: Scarpa, Bruno
name: Dunson, David B.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Applications (stat.AP)
subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: Complex network data problems are increasingly common in many fields of application. Our motivation is drawn from strategic marketing studies monitoring customer choices of specific products, along with co-subscription networks encoding multiple purchasing behavior. Data are available for several agencies within the same insurance company, and our goal is to efficiently exploit co-subscription networks to inform targeted advertising of cross-sell strategies to currently mono-product customers. We address this goal by developing a Bayesian hierarchical model, which clusters agencies according to common mono-product customer choices and co-subscription networks. Within each cluster, we efficiently model customer behavior via a cluster-dependent mixture of latent eigenmodels. This formulation provides key information on mono-product customer choices and multiple purchasing behavior within each cluster, informing targeted cross-sell strategies. We develop simple algorithms for tractable inference, and assess performance in simulations and an application to business intelligence.
A standardized, evidence-based protocol to assess clinical actionability of genetic disorders associated with genomic variation
Creators: name: Buchanan, Adam
name: Martin, Christa Lese
name: Evans, James P.
name: Weaver, Meredith
name: Goddard, Katrina A.B.
name: Piper, Margaret A.
name: Niehaus, Annie D.
name: Scott, Alan F.
name: Berg, Jonathan S.
name: Strande, Natasha
name: Jensen, Brian
name: Hunter, Jessica Ezzell
name: Milko, Laura
name: Slavotinek, Anne
name: Ramos, Erin M.
name: Muessig, Kristin
name: Lee, Kristy
name: Biesecker, Leslie G.
name: Williams, Marc S.
name: Irving, Stephanie A.
name: Sobreira, Nara
name: Webber, Elizabeth M.
name: O'Daniel, Julianne
name: Schully, Sheri D.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Genome and exome sequencing can identify variants unrelated to the primary goal of sequencing. Detecting pathogenic variants associated with an increased risk of a medical disorder enables clinical interventions to improve future health outcomes in patients and their at-risk relatives. The Clinical Genome Resource, or ClinGen, aims to assess clinical actionability of genes and associated disorders as part of a larger effort to build a central resource of information regarding the clinical relevance of genomic variation for use in precision medicine and research.
title: Früherkennung einer axialen Spondyloarthritis bei Patienten mit akuter anteriorer Uveitis
Creators: name: Rademacher, Judith
name: Rodriguez, V. Rios
name: Proft, F.
name: Weber, A.-K.
name: Spiller, L.
name: Muche, B.
name: Pleyer, U.
name: Poddubnyy, D.
Publisher: name: German Medical Science GMS Publishing House
Year: 2018
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Eine akute anteriore Uveitis (AAU) ist die häufigste extra-artikuläre Manifestation bei Patienten mit axialer Spondyloarthritis (axSpA). Zwischen 20-40% der Patienten mit einer AAU haben eine zugrundeliegende axSpA, die oft erst mit einer Zeitverzögerung diagnostiziert[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: Jahrestagung der Berlin-Brandenburgischen Augenärztlichen Gesellschaft 2018
Effect of U.S. Monetary policy shock on GDP of oil-exporting countries A GVAR Approach.
Creators: name: Hajebi, Elnaz
name: Razmi, Seyed Mohammad Javad
name: Mahdavi Adeli, Mohammad Hosein
name: Mohamadi, Teymoor
Publisher: name: figshare
Year: 2022
Subjects: Economics

description: Monetary and financial crisis have different effects on different economies of the world, which in addition to economic factors of countries, depends on the type of their interlinkage in a global economy. Regarding to the importance of U.S. monetary policy in international trade, it is necessary to study the effect of monetary policy shocks of this country on gross domestic product of major oil-exporting countries for determining macroeconomic policies and forecasts in a global and dynamic framework. In this paper we examine the impact of U.S. monetary policy on GDP of major oil-exporting countries in the period of 1974-2017 using GVAR approach. The results indicate that the effect of U.S. Monetary shocks on GDP of these countries is different in short-term and long-term.
Sonnenfleckenzeichnung Nr. 282.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 09.12.1984, 08:30, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
The Effects of the LIBOR Scandal on Volatility and Liquidity in LIBOR Futures Markets
Creators: name: Bachmair, K.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2023
Subjects: LIBOR manipulation scandal
market manipulation
LIBOR discontinuation
LIBOR futures
market microstructure
liquidity
volatility
market reform

description: In 2008, first suspicions arose that the London Interbank Offered Rate (LIBOR) had been systematically manipulated by financial institutions involved with its fixing; in June 2012, several major international banks officially admitted to this. The regulatory response could not have been stronger: the LIBOR was not just reformed but discontinued altogether.

By studying 3-months LIBOR futures, this paper evaluates the consequences four scandal-related events have had on liquidity and volatility in LIBOR markets. The goal is to document the market disruption, or lack thereof, caused by the manipulation and discontinuation and to draw the relevant policy lessons. One finding is that the liquidity outflows necessitated by the discontinuation and the associated volatility increases were confined to a period of a few weeks before the discontinuation, easing potential concerns that market transitions of the scale of LIBOR could only be done at the cost of major and prolonged disruption.
title: Auswirkungen von Polylaktidfolien (Suprathel) auf Burn Wound Conversion und systemische Entzündungsreaktion
Creators: name: Haller, H. L.
name: Sinnig, M.
name: Schriek, K.
name: Sander, F.
name: Hartmann, B.
name: Rapp, M.
name: Pfurtscheller, K.
name: Demircan, M.
name: Blome-Eberwein, S.
name: Wurzer, P.
name: Lumenta, D.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einführung: Die Behandlung von oberflächlichen und partiell tiefen Verbrennungen sowie Entnahmestellen mit Polylactid Folien (Suprathel) hat sich zu einem weitgehend akzeptierten Standard entwickelt. Publizierte Arbeiten der letzten zwei Jahre halfen, den Wirkmechanismus der Polylaktidfolien[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Dilating Loop Relativity: An Examination of Gluon Field Excitation as the Initiating Cause of Time Dilation, Gravity and Dark Matter
Creators: name: Evans, Andrew B.
Publisher: name: Zenodo
Year: 2023
Subjects: gravity, dark matter, time dilation, quantum chromodynamics, Loop Quantum Gravity,

description: Relying on known concepts of General Relativity and quantum field theory, and using the Maxwell and Schwarzschild equations, this paper will investigate how charged gluon spin and subsequent excitation of the gluon field surrounding a gravitational mass result in the dilation of the particulate space of loop quantum gravity and the concurrent dilation of time; generally known as the warping of spacetime, which of course is gravity itself. This paper will also show that for any moving object the bow wave in the gluon field generates an analogous excitation of the field, thus leading to kinetic time dilation, gravity, and a new origin of dark matter. Furthermore, this paper will show that the gravitational behavior of a warped spacetime model based on a weather low pressure system is more appropriate than the commonly envisioned bowling ball in a trampoline. Finally, this paper will present a method of testing and proving this theory by means of frozen hydrogen, polarized with respect to the internal gluon spin.
Crystal Plasticity simulations of complex geometries
Creators: name: Asadkandi, Hassan Moradi
name: Mánik, Tomáš
name: Holmedal, Bjørn
name: Hopperstad, Odd Sture
Publisher: name: Zenodo
Year: 2023
Subjects: Crystal plasticity, CPFEM, Texture Study

description: The implementation of crystal-plasticity-based material models in finite element software can enable precise prediction of the deformation of crystalline materials, by employing a constitutive theory based on the dislocation slip mechanisms. Since modelling the microstructure of a poly-crystalline material requires an adequately fine meshing of the components, the simulation of plastic deformation is only possible if such implementations are robust and effective. This is especially of great importance in the case of using an explicit integration scheme for the finite element solver. This study presents a new technique for preparing models with complex geometry that contain grain orientation information and are suitable for use in the finite element software Abaqus. By implementing stable and robust user material subroutines, it is now possible to simulate large plastic deformation in small-scale structural components. Selected cases are discussed.
title: Einsetzbarkeit und Positionierung von Polylactid Folien (Suprathel) bei Großschadensereignissen
Creators: name: Haller, H. L.
name: Giretzlehner, M.
name: Thumfart, S.
name: Rapp, M.
name: Sander, F.
name: Hartmann, B.
name: Wurzer, P.
name: Lumenta, D.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Großschadensereignisse mit Brandverletzungen stellen eine ständige Bedrohung unserer Gesellschaft dar, die in den letzten Jahren durch die Möglichkeit terroristischer Anschläge zugenommen hat. Die Bewältigung solcher Ereignisse erfordert nicht nur die Befassung mit[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
title: Die Aufnahme von PHMB in epicitehydro(R)
Creators: name: Holzer, J. C. J.
name: Tuca, A.-C.
name: Bernadelli de Mattos, I.
name: Groeber-Becker, F.
name: Funk, M.
name: Popp, D.
name: Mautner, S.
name: Birngruber, T.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Die stetige Zunahme von Antibiotikaresistenzen ist besonders für VerbrennungspatientInnen relevant, da diese oft sehr große Wundflächen aufweisen und oft mit Wundinfektionen zu kämpfen haben. 43% der Verbrennungspezialisten aus der ganzen Welt sind sich einig, dass[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Daß die Armut in weiten Gebieten Asiens durch die gemeinsamen Anstrengungen der christlichen Nationen überwunden werde
Publisher: name: Herder Korrespondenz
Year: 1970

description: Herder Korrespondenz, Bd. 20 Nr. 2 (1966): Herder Korrespondenz, Band 20, Heft 2
title: Kontrollfall bezüglich der Anwendung von Dressilk bei einer 73-jährigen polypathologischen Patientin
Creators: name: Stanese, F.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einführung: Patienten mit assoziierten Pathologien weisen einen erschwerenden Faktor bei der Wundheilung auf. Hier wird über einen Kontrollfall mit dem Dressilk®-Verband bei einem venösen Ulkus Typ III einer Patientin berichtet, die 2013 eine Mitral- und Trikuspidalklappenprothese[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Fossil basicranium clarifies the origin of the avian central nervous system and inner ear.
Creators: name: Navalón, Guillermo
name: Chiappe, Luis M
name: Martinelli, Agustín G
name: Nava, William
name: Field, Daniel J
Publisher: name: Apollo - University of Cambridge Repository
Year: 2022
Subjects: Ear
Dinosaurs
Brains
Birds
Labyrinth
Endocranium
Skull Base
Brain
Animals
Mammals
Phylogeny
Fossils
Ear, Inner
Biological Evolution

description: Among terrestrial vertebrates, only crown birds (Neornithes) rival mammals in terms of relative brain size and behavioural complexity. Relatedly, the anatomy of the avian central nervous system and associated sensory structures, such as the vestibular system of the inner ear, are highly modified with respect to those of other extant reptile lineages. However, a dearth of three-dimensional Mesozoic fossils has limited our knowledge of the origins of the distinctive endocranial structures of crown birds. Traits such as an expanded, flexed brain, a ventral connection between the brain and spinal column, and a modified vestibular system have been regarded as exclusive to Neornithes. Here, we demonstrate all of these 'advanced' traits in an undistorted braincase from an Upper Cretaceous enantiornithine bonebed in southeastern Brazil. Our discovery suggests that these crown bird-like endocranial traits may have originated prior to the split between Enantiornithes and the more crownward portion of avian phylogeny over 140 Ma, while coexisting with a remarkably plesiomorphic cranial base and posterior palate region. Altogether, our results support the interpretation that the distinctive endocranial morphologies of crown birds and their Mesozoic relatives are affected by complex trade-offs between spatial constraints during development.
Sonnenfleckenzeichnung Nr. 293.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.12.1984, 10:00, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Section E6.1–6.4 of the ACMG technical standards and guidelines: chromosome studies of neoplastic blood and bone marrow–acquired chromosomal abnormalities
Creators: name: Mikhail, Fady M.
name: Cooley, Linda D.
name: Heerema, Nyla A.
name: Burnside, Rachel D.
name: Cherry, Athena M.
name: Rao, Kathleen W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: DISCLAIMER: These American College of Medical Genetics and Genomics standards and guidelines are developed primarily as an educational resource for clinical laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does not necessarily ensure a successful medical outcome. These standards and guidelines should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results. In determining the propriety of any specific procedure or test, the clinical laboratory geneticist should apply his or her own professional judgment to the specific circumstances presented by the individual patient or specimen. Clinical laboratory geneticists are encouraged to document in the patient's record the rationale for the use of a particular procedure or test, whether or not it is in conformance with these standards and guidelines. They also are advised to take notice of the date any particular guideline was adopted, and to consider other relevant medical and scientific information that becomes available after that date. It also would be prudent to consider whether intellectual property interests may restrict the performance of certain tests and other procedures.Cytogenetic analyses of hematological neoplasms are performed to detect and characterize clonal chromosomal abnormalities that have important diagnostic, prognostic, and therapeutic implications. At the time of diagnosis, cytogenetic abnormalities assist in the diagnosis of such disorders and can provide important prognostic information. At the time of relapse, cytogenetic analysis can be used to confirm recurrence of the original neoplasm, detect clonal disease evolution, or uncover a new unrelated neoplastic process. This section deals specifically with the standards and guidelines applicable to chromosome studies of neoplastic blood and bone marrow-acquired chromosomal abnormalities. This updated Section E6.1-6.4 has been incorporated into and supersedes the previous Section E6 in Section E: Clinical Cytogenetics of the 2009 Edition (Revised 01/2010), American College of Medical Genetics and Genomics Standards and Guidelines for Clinical Genetics Laboratories.Genet Med 18 6, 635-642.
Thermoelectric Amplification of Phonons in Graphene
Creators: name: Dompreh, K. A.
name: Mensah, S. Y.
name: Mensah, N. G.
name: Fosuhene, S. K.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Amplification of acoustic phonons due to an external temperature gredient ($\nabla T$) in Graphene was studied theoretically. The threshold temperature gradient $(\nabla T)_0^{g}$ at which absorption switches over to amplification in Graphene was evaluated at various frequencies $ω_q$ and temperatures $T$. For $T = 77K$ and frequency $ω_q = 12THz$, $(\nabla T)_0^{g} = 0.37Km^{-1}$. The calculation was done in the regime at $ql >> 1$. The dependence of the normalized ($Γ/Γ_0$) on the frequency $ω_q$ and the temperature gradient $(\nabla T/T)$ are evaluated numerically and presented graphically. The calculated $(\nabla T)_0^{g}$ for Graphene is lower than that obtained for homogeneous semiconductors ($n-InSb$) $(\nabla T)_0^{hom} \approx 10^3Kcm^{-1}$, Superlattices $(\nabla T)_0^{SL} = 384Kcm^{-1}$, Cylindrical Quantum Wire $(\nabla T)_0^{cqw} \approx 10^2Kcm^{-1}$. This makes Graphene a much better material for thermoelectric phonon amplifier.
description: 12 Pages, 6 figures
Topological polaritons from photonic Dirac cones coupled to excitons in a magnetic field
Creators: name: Yi, Kexin
name: Karzig, Torsten
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We introduce an alternative scheme for creating topological polaritons (topolaritons) by exploiting the presence of photonic Dirac cones in photonic crystals with triangular lattice symmetry. As recently proposed, topolariton states can emerge from a coupling between photons and excitons combined with a periodic exciton potential and a magnetic field to open up a topological gap. We show that in photonic crystals the opening of the gap can be substantially simplified close to photonic Dirac points. Coupling to Zeeman-split excitons breaks time reversal symmetry and allows to gap out the Dirac cones in a non-trival way, leading to a topological gap similar to the strength of the periodic exciton potential. Compared to the original topolariton proposal [Karzig {\em et al}, PRX {\bf 5}, 031001 (2015)], this scheme significantly increases the size of the topological gap over a wide range of parameters. Moreover, the gap opening mechanism highlights an interesting connection between topolaritons and the Haldane and Raghu scheme [Haldane and Raghu, PRL {\bf 100}, 013904 (2008)] to create topological photons in magneto-optically active materials.
description: 6 pages, 5 figures, v2: extra section comparing different topological photon/polariton schemes
title: Kontinuierliches pH-Monitoring mittels kombiniertem Indikator-Verband – eine Machbarkeitsstudie
Creators: name: Nischwitz, S. P.
name: Bernardelli de Mattos, I.
name: Hofmann, E.
name: Funk, M.
name: Mohr, G.
name: Branski, L.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Hintergrund: Die moderne Verbrennungsmedizin strebt nach Mitteln, um eine optimale Wundheilung zu gewährleisten. In diversen Studien konnte eine Korrelation zwischen pH-Wert im Wundmilieu und erfolgreicher Wundheilung gezeigt werden. Ziel dieser Studie war, eine sterile und einfach anzuwendende[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 227.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.09.1984, 08:15, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Großflächige Wundunterdrucktherapie bei Schwerbrandverletzten
Creators: name: Wallner, B.
name: Öhlbauer, M.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Grundlagen: Seit über 10 Jahren wird die Wundunterdrucktherapie (NPWT) bei Brandverletzten konzeptionell und standardisiert angewendet. Insbesondere die großflächige Anwendung der Wundunterdrucktherapie bei Schwerbrandverletzten hat uns vor besondere Aufgaben gestellt. Kosten, Nutzen[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
The promise and peril of genomic screening in the general population
Creators: name: Evans, James P.
name: Adams, Michael C.
name: Henderson, Gail E.
name: Berg, Jonathan S.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2016

description: Utilization of sequencing to screen the general population for preventable monogenic conditions is receiving substantial attention due to its potential to decrease morbidity and mortality. However, the selection of which variants to return is a serious implementation challenge. Procedures must be investigated to ensure optimal test characteristics and avoidance of harm from false positive test results.
Sonnenfleckenzeichnung Nr. 233.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 26.09.1984, 08:00, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 291.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.12.1984, 09:30, erstellt von Sergio Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Einfluss von sekundären Wundauflagen auf die Wirkung von Epicite Hydro: Ergebnisse einer tierexperimentellen Studie
Creators: name: Tuca, A.-C.
name: Holzer, J. C. J.
name: Funk, M.
name: Palackic, A.
name: Bernardelli de Mattos, I.
name: Groeber-Becker, F.
name: Birngruber, T.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Eine ausgewogene feuchte Wundumgebung und Wundoberfläche erleichtern die Wirkung von diversen Wachstumsfaktoren, Zytokinen und Chemokinen und beeinflussen dadurch das Zellwachstum. Dadurch können das Zellwachstum und die Wundheilung angeregt und beschleunigt werden. Angesichts [zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Sonnenfleckenzeichnung Nr. 292.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.12.1984, 10:15, erstellt von Marco Cortesi, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Peptide Nucleic Acids (PNA)-Based Structures for Nanotechnology and Biodetection Applications
Creators: name: Pearse, Alexander
Publisher: name: Carnegie Mellon University
Year: 2023
Subjects: subject: 30201 Bioinorganic Chemistry
subject: FOS: Chemical sciences
subject: 30302 Nanochemistry and Supramolecular Chemistry

description: This thesis incorporates projects within the field of nucleic acid nanotechnology and targets DNA G-Quadruplexes (GQ) within a biological context. Due to the synthesis and use of peptide nucleic acids (PNA). Specifically, PNA is coupled to metal binding ligands and used to form Watson and Crick (WC) base pairs with an oxidized guanine base. Chapter 1 introduces DNA, PNA, metal-mediated PNA, and their incorporation into the large nucleic acid nanostructure. This chapter also explores the unique characteristics of each type of nucleic acid and of the structures they form. It concludes by setting up the introductory metalmediated nanostructure to be synthesized. Chapter 2 shows the construction and confirmation of tiles bridged by [CuQ2] complexes. The metal-bridged DNA/PNA tiles are more stable than the “traditional” tiles based exclusively on DNA strands. Thermal melting studies show that incorporating PNA rails in the DNA tiles increases the tile stability even in the absence of metal ions. The metal complex formation did not substantially impact the tile stability. Metal titrations show the Cu2+coordination to 8-hydroxyquinoline (Q) ligands. UV-vis titrations give a lower M/L ratio than the 0.5 expected if [CuQ2] complexes formed in the tile. Spin quantification by EPR shows that all PNA-Q strands participated in the formation of complexes with Cu2+. Future studies will be focused on the design and imaging of larger metal-containing DNA/PNA tiles. Chapter 3 builds from this by using DNA sticky-ends to link tiles together into wires, which were shown to have similar stabilities as the tiles. AFM studies of DNA(SE) show that DNA hybridization can connect tiles into wires. Wires were also synthesized with [CuQ2] at the terminal ends of a duplex, and wire formation occurred through complexation instead of nucleic acid crossovers. Metal titrations confirm the formation of the complex. Chapter 4 departs from nanostructures to using PNA to target oxidized guanine (OxoG) base. The OxoG destabilizes the GQ and therefore exposes it to duplex attack. Preliminary results for this project show duplex formation even to the non-Oxo GQ. Lastly, Chapter 5 explores the next steps in these projects, delving into the future work and what the potential future of these projects could entail.
A survey of current practices for genomic sequencing test interpretation and reporting processes in US laboratories
Creators: name: Das, Soma
name: Farwell Hagman, Kelly D.
name: Amendola, Laura M.
name: Jarvik, Gail P.
name: Shirts, Brian H.
name: Spinner, Nancy B.
name: Bale, Sherri J.
name: Berg, Jonathan S.
name: Holm, Ingrid A.
name: Bowling, Kevin M.
name: Hambuch, Tina
name: Wolf, Susan M.
name: Richards, C. Sue
name: Plon, Sharon E.
name: Deignan, Joshua L.
name: Ghazani, Arezou A.
name: Yang, Yaping
name: Chao, Elizabeth C.
name: Conlin, Laura K.
name: Dorschner, Michael O.
name: Rehm, Heidi L.
name: Punj, Sumit
name: Knight Johnson, Amy
name: McLaughlin, Heather M.
name: Tang, Sha
name: Evans, James P.
name: Bick, David
name: Hegde, Madhuri
name: Weck, Karen E.
name: Hindorff, Lucia A.
name: Santani, Avni
name: Morra, Massimo
name: Chung, Wendy K.
name: Mighion, Lindsey
name: Goddard, Katrina A.
name: Cooper, Gregory M.
name: Gornick, Michele
name: O'Daniel, Julianne M.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2017

description: While the diagnostic success of genomic sequencing expands, the complexity of this testing should not be overlooked. Numerous laboratory processes are required to support the identification, interpretation and reporting of clinically significant variants. This study aimed to examine workflow and reporting procedures among US laboratories to highlight shared practices and identify areas in need of standardization.
Sonnenfleckenzeichnung Nr. 229.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 21.09.1984, 12:15, erstellt von Michele Bianda, Sonnenobservatorium Specola Solare Ticinese in Locarno
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1984

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
title: Granulox(R) – Eine Sicherheitsstudie
Creators: name: Holzer, J. C. J.
name: Birngruber, T.
name: Mautner, S.
name: Kamolz, L.-P.
Publisher: name: German Medical Science GMS Publishing House
Year: 2019
Subjects: subject: 610 Medical sciences; Medicine

description: Einleitung: Chronische Wunden sind auf der gesamten Welt eine große therapeutische Herausforderung, da die Entstehungsmechanismen zumeist unbekannt sind. Häufig liegt eine Störung der Sauerstoffzufuhr zugrunde, verursacht durch diverse Grunderkrankungen der PatientInnen. Granulox(R)[zum vollständigen Text gelangen Sie über die oben angegebene URL]
description: 37. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2019)
Efficient implicit integration for finite-strain viscoplasticity with a nested multiplicative split
Creators: name: Shutov, A. V.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 74C20, 65L80, 74S05

description: An efficient and reliable stress computation algorithm is presented, which is based on implicit integration of the local evolution equations of multiplicative finite-strain plasticity/viscoplasticity. The algorithm is illustrated by an example involving a combined nonlinear isotropic/kinematic hardening; numerous backstress tensors are employed for a better description of the material behavior. The considered material model exhibits the so-called weak invariance under arbitrary isochoric changes of the reference configuration, and the presented algorithm retains this useful property. Even more: the weak invariance serves as a guide in constructing this algorithm. The constraint of inelastic incompressibility is exactly preserved as well. The proposed method is first-order accurate. Concerning the accuracy of the stress computation, the new algorithm is comparable to the Euler Backward method with a subsequent correction of incompressibility (EBMSC) and the classical exponential method (EM). Regarding the computational efficiency, the new algorithm is superior to the EBMSC and EM. Some accuracy tests are presented using parameters of the aluminum alloy 5754-O and the 42CrMo4 steel. FEM solutions of two boundary value problems using MSC.MARC are presented to show the correctness of the numerical implementation.
description: 33 pages, 12 figures