cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Elevated Nerve Growth Factor and its Receptor Levels in Endometriotic Tissues are Associated with Deep Dyspareunia
Creators: name: Peng, Bo
name: Zhan, Hong
name: Alotaibi, Fahad
name: Alkusayer, Ghadeer M.
name: Bedaiwy, Mohamed Ali, 1968-
name: Yong, Paul J.
Publisher: name: The University of British Columbia
Year: 2019

description: CONTEXT; Deep dyspareunia (pelvic pain with sexual intercourse) affects half of women with endometriosis, but the underlying mechanisms are unclear. OBJECTIVE: To investigate whether nerve growth factor (NGF) and its receptor (TrkA/p75NTR) levels in endometriotic tissues are elevated in women with deep dyspareunia. DESIGN: In vitro study. SETTING: University hospital affiliated research laboratories. PATIENTS: 34 women with endometriosis in the posterior pelvic compartment (cul-de-sac/uterosacrals) were included, either with (n=18) or without (n=16) deep dyspareunia symptoms which was confirmed by endovaginal ultrasound-assisted palpation on examination. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Utilizing surgically excised cul-de-sac/uterosacral endometriosis, expression of NGF/TrkA/p75NTR was examined by immunohistochemistry and Histoscore. Cultured endometriotic stromal cells (ESCs, n=3) were incubated with/without NGF and/or Trk inhibitor K252a. Prostaglandin-endoperoxide synthase-2 (PGST-2/COX-2) mRNA and protein levels were examined by RT-qPCR and Western blot, respectively. Prostaglandin E2 (PGE2) secretion were examined by ELISA. RESULTS: NGF/TrkA/p75NTR were expressed in the epithelium and stroma of the cul-de- sac/uterosacral endometriosis, and were significantly elevated in women with deep dyspareunia compared to women without deep dyspareunia. NGF immunoreactivity in the stroma was also significantly associated with deep dyspareunia severity and with nerve bundle density. In cultured ESCs, NGF significantly increased PTGS-2/COX-2 mRNA and protein levels as well as PGE2 secretion, and these effects could be abolished by pretreatment of K252a. CONCLUSIONS: Elevated NGF/TrkA/p75NTR levels may be associated with sexual pain (deep dyspareunia) in women with cul-de-sac/uterosacral endometriosis. This association may be mediated by an increase in nerve bundle density and by COX-2 and PGE2 stimulation via Trk receptor.
An investigation into the influence of situational components in hospitality retailing
Creators: name: O'Mahony, Barry
name: Hall, John
name: Binney, Wayne
name: Hede, Anne-Marie
Publisher: name: Swinburne
Year: 2024

description: Although the importance of situational influences on consumer behaviour has been recognised for some time, little research has been conducted into their effects in hospitality retailing. Over the past decade the Irish theme pub sector has enjoyed extensive growth, which recent studies attribute to the situational components inherent within the environment. This study sought to identify and evaluate the situational components that influence consumers within Irish theme pubs and to gauge the influence of each of the dimensions of an established situational model on customer behaviour among gender and age cohorts. A three phase, mixed method research design was used and respondents were selected from six Irish theme pubs in Melbourne. The study found that both physical and social situational components have a significant influence in attracting, serving and satisfying the needs of consumers.
Three-stage Hermite-Birkhoff-Taylor ODE solver with a C++ program
Creators: name: Bozic, Vladan
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Mathematics.

description: One-step 3-stage Hermite-Birkhoff-Taylor methods, denoted by HBT( p)3, are constructed for solving nonstiff systems of first-order differential equations of the form y' = f( x, y), y(x0) = y0. The method uses derivatives y' to y(p--2) as in Taylor methods and is combined with a 3-stage Runge-Kutta method of order 3. Forcing a Taylor expansion of the numerical solution to agree with an expansion of the true solution leads to Taylor- and Runge-Kutta-type order conditions, which are then reorganized into Vandermonde-type linear systems whose solutions are the coefficients of the method. The new method yields impressive results with regards to intervals of absolute stability. A detailed formulation of variable step size (VS) fixed order HBT( p)3 is presented, as well as the formulation of variable-step variable-order (VSVO) HBT(p)3. Several problems often used to test high order ODE solvers on the basis the number of steps, CPU time, maximum global error, and maximum global energy error are considered. The results stress that both VS and VSVO HBT(p)3 methods are superior to Dormand-Prince DP (8,7)13M and Taylor method of order p, denoted by T( p). To obtain results at high precision, high order VS and VSVO HBT( p)3 methods have been implemented in multiple precision. These numerical results clearly show the benefit of formulating a method by adding high order derivatives to Runge-Kutta method.
Ermittlung der Schadstoff- und Klimagasemissionen von Pkw und leichten Nutzfahrzeugen durch WLTP und RDE unter Berücksichtigung zukünftiger Kraftstoffe und Antriebskonzepte
Creators: name: Badur, Jens
Publisher: name: My University
Year: 2019
Subjects: subject: Fahrzyklus
subject: Kohlendioxid
subject: Abgas
subject: Luftschadstoff
subject: Personenkraftwagen
subject: Kfz-Abgas
subject: Steckdosen-Hybridauto
subject: CO2
subject: WLTP
subject: RDE
subject: Luftschadstoff-Emissionen
subject: Luftschadstoffausstoß
subject: PKW
subject: Leichte Nutzfahrzeuge
subject: Autoabgas
subject: Hybrid-Fahrzeuge
subject: Plug-in Hybrid
subject: Verkehr

description: Extern aufladbare Hybridelektro-Pkw, sogenannte Plug-in-Hybride, werden zur Erreichung der Flottenzielwerte für CO2 in der EU zukünftig stärker in den Markt kommen müssen. Es ist notwendig, dass auch diese Fahrzeuge im praktischen Betrieb auf der Straße nur möglichst geringe Mengen der verschiedenen Schadstoffe ausstoßen und die CO2-Emissionen möglichst realistisch bestimmt werden. Im Vorhaben wurde ein Plug-in-Hybrid-Pkw in Messungen auf dem Prüfstand und auf der Straße umfassend bezüglich des Emissionsverhaltens charakterisiert. Das Vorhaben lief parallel zur Weiterentwicklung der Abgasgesetzgebung auf EU-Ebene durch RDE und WLTP. Die Ergebnisse flossen in die entsprechenden Prozesse ein.
Neoponera foetida
Creators: name: Arredondo, Brandon S.
name: Carreño-Guevara, Yennifer
name: Gutierrez-Villanueva, Yenifer
name: Duran-Bautista, Ervin Humprey
name: Gamboa-Tabares, Jean
name: Guerrero, Roberto J.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Neoponera
Neoponera foetida

description: Neoponera foetida (Linnaeus, 1758)
Distribution
Amazonas, Antioquia, Caquetá, Cauca, Meta, Valle del Cauca (Fernández et al. 2019).
description: Published as part of Arredondo, Brandon S., Carreño-Guevara, Yennifer, Gutierrez-Villanueva, Yenifer, Duran-Bautista, Ervin Humprey, Gamboa-Tabares, Jean & Guerrero, Roberto J., 2025, Soil and leaf litter ants from the Amazon Region offer new distribution records for Colombia, pp. e 142813 in Biodiversity Data Journal 13 on page e142813, DOI: 10.3897/BDJ.13.e142813
Some intuitionist principles in the free topos
Creators: name: Wares, Trevor
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Mathematics.

description: Brouwer's principle/theorem states that all total functions R→R are continuous. Obviously not classically true this result was a theorem of Brouwer in his intuitionistic setting. The formalization(s) of intuitionistic logic provides us with systems of logic in which to ask is this principle provable? In a higher order setting (e.g. higher order type theory) one has two ways of expressing this principle. First is simply the statement ⊢∀f&parl0;f:R&rarrr; R⇒'' fiscontinuous'' &parr0; Second is as a meta theorem ⊢f:R→R⊢'' fis continuous'' In this work we present a categorical proof that the second formulation holds in higher order Heyting arithmetic (HAH). Our proof is general enough however to obtain the same continuity principle with R replaced by a "sufficiently nice" space S, a notion which is made precise.
Neoponera laevigata
Creators: name: Arredondo, Brandon S.
name: Carreño-Guevara, Yennifer
name: Gutierrez-Villanueva, Yenifer
name: Duran-Bautista, Ervin Humprey
name: Gamboa-Tabares, Jean
name: Guerrero, Roberto J.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Neoponera
Neoponera laevigata

description: Neoponera laevigata (Smith, 1858)
Distribution
Amazonas, Caquetá, Chocó, Cundinamarca, Putumayo, Valle del Cauca (Fernández et al. 2019).
description: Published as part of Arredondo, Brandon S., Carreño-Guevara, Yennifer, Gutierrez-Villanueva, Yenifer, Duran-Bautista, Ervin Humprey, Gamboa-Tabares, Jean & Guerrero, Roberto J., 2025, Soil and leaf litter ants from the Amazon Region offer new distribution records for Colombia, pp. e 142813 in Biodiversity Data Journal 13 on page e142813, DOI: 10.3897/BDJ.13.e142813
Neoponera obscuricornis
Creators: name: Arredondo, Brandon S.
name: Carreño-Guevara, Yennifer
name: Gutierrez-Villanueva, Yenifer
name: Duran-Bautista, Ervin Humprey
name: Gamboa-Tabares, Jean
name: Guerrero, Roberto J.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Neoponera
Neoponera obscuricornis

description: Neoponera obscuricornis (Emery, 1890)
Distribution
Amazonas, Antioquia, Caquetá, Chocó, Meta, Valle del Cauca, Vichada (Fernández et al. 1996, Fernández et al. 2019).
description: Published as part of Arredondo, Brandon S., Carreño-Guevara, Yennifer, Gutierrez-Villanueva, Yenifer, Duran-Bautista, Ervin Humprey, Gamboa-Tabares, Jean & Guerrero, Roberto J., 2025, Soil and leaf litter ants from the Amazon Region offer new distribution records for Colombia, pp. e 142813 in Biodiversity Data Journal 13 on page e142813, DOI: 10.3897/BDJ.13.e142813
The extra-virgin olive oil polyphenols oleocanthal and oleacein counteract inflammation-related gene and miRNA expression in adipocytes by attenuating NF-κB activation
Creators: name: Carpi, Sara
name: Scoditti, Egeria
name: Massaro, Marika
name: Polini, Beatrice
name: Manera, Clementina
name: Digiacomo, Maria
name: Esposito Salsano, Jasmine
name: Poli, Giulio
name: Tuccinardi, Tiziano
name: Doccini, Stefano
name: Santorelli, Filippo Maria
name: Carluccio, Maria Annunziata
name: Macchia, Marco
name: Wabitsch, Martin
name: De Caterina, Raffaele
name: Nieri, Paola
Publisher: name: Universität Ulm
Year: 2019
Subjects: subject: Extra-virgin olive oil
subject: Oleocanthal
subject: Oleacein
subject: NF-κB
subject: DDC 570 / Life sciences
subject: DDC 610 / Medicine & health
subject: Adipocytes
subject: Exosomes
subject: Gene expression
subject: Inflammation
subject: Obesity
subject: MicroRNAs
subject: NF-kappa B
subject: Fettzelle
subject: Exosom
subject: Genexpression
subject: Entzündung
subject: Übergewicht
subject: miRNS
subject: Nuklearfaktor Kappa B

description: Inflammation of the adipose tissue plays an important role in the development of several chronic diseases associated with obesity. Polyphenols of extra virgin olive oil (EVOO), such as the secoiridoids oleocanthal (OC) and oleacein (OA), have many nutraceutical proprieties. However, their roles in obesity-associated adipocyte inflammation, the NF- B pathway and related sub-networks have not been fully elucidated. Here, we investigated impact of OC and OA on the activation of NF- B and the expression of molecules associated with inflammatory and dysmetabolic responses. To this aim, fully di erentiated Simpson-Golabi-Behmel syndrome (SGBS) adipocytes were pre-treated with OC or OA before stimulation with TNF- . EVOO polyphenols significantly reduced the expression of genes implicated in adipocyte inflammation (IL-1 , COX-2), angiogenesis (VEGF/KDR, MMP-2), oxidative stress (NADPH oxidase), antioxidant enzymes (SOD and GPX), leukocytes chemotaxis and infiltration (MCP-1, CXCL-10, MCS-F), and improved the expression of the anti-inflammatory/metabolic e ector PPAR . Accordingly, miR-155-5p, miR-34a-5p and let-7c-5p, tightly connected with the NF- B pathway, were deregulated by TNF- in both cells and exosomes. The miRNA modulation and NF- B activation by TNF- was significantly counteracted by EVOO polyphenols. Computational studies suggested a potential direct interaction between OC and NF- B at the basis of its activity. This study demonstrates that OC and OA counteract adipocyte inflammation attenuating NF- B activation. Therefore, these compounds could be novel dietary tools for the prevention of inflammatory diseases associated with obesity.
Challenges of Water Supply Management in Rural Communities
Creators: name: Hassan, Nik Muhammad Nizam Nik
name: Hunter, Paul
name: Lake, Iain
name: Rohaida Ismail
Publisher: name: Zenodo
Year: 2020
Subjects: Challenges
Water
Supply
Management
Rural

description: Introduction Globally, management of rural, small community drinking water supply faces a lot of hurdles. According to the Millennium Development Goal (MDG) report, disparities in access to safe drinking water remain between rural and urban population. A systematic review was conducted on the challenges of rural drinking water supply management from source to tap. The aim of the review is to discover best practices and explore the different strategies in small rural communities’ water supply management. Methods The review searched three online databases, Ovid, Web of Science and Cochrane Library for studies that evaluated rural drinking water supply or small-community water supply managements using 4 groups of key terms; “evaluation or assessment”, “management or intervention”, “drinking water or water supply”, and “rural or small communities”. Selection and exclusion criteria Scope covers management between source to tap. Include any study design. Papers must have; i) a clear description of the intervention being studied ii) a clear description of the evaluation method used. Results In total 15 papers were selected, consisting of 3 cross sectional studies, 2 case studies, 2 longitudinal studies, 3 quasi experimental and 5 cost effectiveness or cost benefit analysis modelling. Selected studies included 11 different countries involving almost all types of improved water supply technology and 31, 094 different water points. Positive management traits identified included committees with regular servicing (P<0.01) and periodic financial audit (P<0.01). Programs involving intervention have 42% higher percentage of functional water systems compared to control. The papers also showed cost effectiveness and positive cost benefit of proper rural water managements. Discussions / Conclusion The review suggests that sustainability of rural water supply system depends on certain positive management aspects and effective management committees. It also showed that rural water interventions should be hands on with a sense of ownership to maintain functionality. The benefits of rural drinking water management were also shown to outweigh the cost.
Depression. Depression – Ratgeber für Angehörige.
Creators: name: Ärztliches Zentrum Für Qualität In Der Medizin (ÄZQ)
Publisher: name: Bundesärztekammer (BÄK); Kassenärztliche Bundesvereinigung (KBV); Ärztliches Zentrum für Qualität in der Medizin (ÄZQ)
Year: 2011
Subjects: subject: 610 Medical sciences; Medicine

description: Kurzinformationen für Patienten
Solubilities of oxygen in selected alkane solvents and in aqueous copper electrorefining solutions.
Creators: name: Manku, Gurdev.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Chemical.

description: The equilibrium solubilities of oxygen were determined in aqueous solutions which were made to simulate solutions typically found in electrorefining processes to obtain ultrapure copper. The electrorefining solutions were composed of 30 g/L Cu$\sp{+2}$/150 g/L $\rm H\sb2SO\sb4$ and 60 g/L Cu$\sp{+2}$/150 g/L $\rm H\sb2SO\sb4$. The solubilities of oxygen were also determined in aqueous solutions containing 30 g/L Cu$\sp{+2}$, 60 g/L Cu$\sp{+2}$, 75 g/L $\rm H\sb2SO\sb4$, and 150 g/L $\rm H\sb2SO\sb4$. The solution of oxygen were determined in these solutions at a temperature of 333.15 K and at atmospheric pressure. In addition, the densities of the aqueous solvent solutions were measured in the temperature range between 313.15 K and 413.15 K. Further, the vapor pressures of the copper sulphate-sulphuric acid solutions were determined at a temperature of 333.15 K. The solubilities of oxygen in the aqueous solutions were found to be very low, on the order of 10$\sp{-5}$ mole fraction, for an oxygen partial pressure of 101.325 kPa. Addition of electrolytes to water, such as the sulphuric acid and the copper sulfate salt, salted out the oxygen. The solution containing 60 g/L Cu$\sp{+2}$ and 150 g/L H$\sb2$SO$\sb4$ exhibited a decrease in oxygen solubility of approximately 53% as compared with the solubility of oxygen in pure water. (Abstract shortened by UMI.)
title: Estudio Pictórico de la Escoliosis con TC
Creators: name: Rozas Rodríguez, María Librada
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT
subject: Computer Applications-3D
subject: Congenital
subject: Dysplasias

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Demostrar la utilidad del TC en el estudio de la...
Disclosing a hepatitis C diagnosis: stigmatised if you do, isolated if you don’t
Creators: name: Fry, Margeret
name: Bates, Glen
Publisher: name: Swinburne
Year: 2024

description: The hepatitis C virus (HCV) is the leading notifiable disease in Australia.It is described as a stigmatised disease, as the majority of new infections are associated with intravenous drug use.The current qualitative study explored the lived experiences of those diagnosed with HCV.Fifteen participants (10 women and 5 men) who were HCV positive and not current drug users were interviewed about the impact of their diagnosis and how they have adjusted to it.The data were analysed using open and closed coding methods.Diagnosis was found to be a traumatic experience with considerable emotional impact that could be exacerbated by stigma, discrimination and a lack of information.Support is provided for a selfmanagement construct encompassing medical, emotional and life role facets.It was concluded that positive reactions to disclosure contribute to adjustment, whereas perceptions of stigma and negative reactions to disclosure may create barriers to self-management and personal growth.
title: Revisión de los hallazgos radiológicos de la diverticulitis aguda y sus complicaciones
Creators: name: García Carriazo, Mercedes
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Colon
subject: CT
subject: Ultrasound

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Describir los hallazgos radiológicos (en ecografía,
enema opaco y fundamentalmente en la TC) de la diverticulitis aguda así como los de sus complicaciones,
basados en la clasificación radiológica por TC y en la clasificación de...
Sickle cell disease in the emergency department Predictors of adverse outcomes: A prospective cohort study
Creators: name: Al Reesi, Abdullah
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Health Sciences, Epidemiology.

description: Introduction. Current evidence does not provide a clear risk stratification strategy for sickle cell disease patients in the emergency department (ED). The goal of this study was to develop a better understanding of the clinical features among patients with sickle cell disease and to determine the risk factors for short term adverse events. Methods. We conducted a prospective cohort study of sickle cell disease patients presenting to a tertiary care ED over six consecutive months. All patients were assessed by emergency physicians during the ED visit. All the patients had a 2 week structured telephone follow-up or a chart review if they had a repeat ED visit within 2 weeks or admitted. The adverse outcomes were classified as a clinically significant outcome (death, cerebrovascular accidents, acute chest syndrome, sepsis, hyper-hemolytic crisis and exchange blood transfusion) or not. We also classified patients as having acute chest syndrome or not. We analyzed the predictors of adverse outcomes using descriptive statistics and multiple logistic regression. Results. Over six consecutive months, we enrolled 732 patients. Seventy-five patients had a clinically significant outcome and 42 had acute chest syndrome. Using multivariate analysis, we found nine statistically significant predictors of a clinically significant adverse outcome: a prolonged painful episode (OR 10.1; 95%CI 5.3-19.3), age less than 8 years (OR 2.4; 95%CI 1.001 -5.9), oxygen saturation less than 96% (OR 3.9; 95%CI 1.6-10.9), patient appearing toxic (OR 7.8; 95%CI 2.2-27.2), presence of chest crackles (OR 6.5; 95%CI 2.3-18.6), splenomegaly (OR 2.6; 95%CI 1.2-5.5), local limb tenderness (OR 0.2; 95%CI 0.08-0.7), hemoglobin less than 7 g/dL (OR 3.6; 95%CI 1.1-11.6), reticulocyte count more than 15% (OR 4.0; 95%CI 1.4-11.5). Using multivariate analysis, we found seven statistically significant predictors of acute chest syndrome: a prolonged painful episode (OR 22.0; 95%CI 8.7-55.3), oxygen saturation less than 92% (OR 17.7; 95%CI 1.7-184.9), history of cough (OR 4.5; 95%CI 1.7-12.0), history of pneumococcal vaccine (OR 0.33; 95%CI 0.11-0.98), presence of chest crackles (OR 9.5; 95%CI 2.6-34.7), local limb tenderness (OR 0.20; 95%CI 0.05-0.80), and reticulocyte count more than 15% (OR 4.9; 95%CI 1.2-19.7). Conclusion. Our study of a tertiary hospital emergency department found nine identifiable variables which can help to predict the possibility of developing a clinically significant outcome. We also found seven identifiable variables which can help to predict the possibility of developing acute chest syndrome. This might be used in the future to risk stratify the sickle cell disease patients who presents to the emergency department and develop strategies to prevent those adverse outcomes.
title: Ataxia autosómica recesiva espastica de Charlevoix-Saguenay (ACS). ¿Que aporta la secuencia de Tensor de Difusión en su diagnóstico y caracterización?
Creators: name: Vela, Ana
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: MR-Diffusion/Perfusion
subject: MR

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Recordar los hallazgos por RM de la ataxia de Charlevoix-Saguenay . Mostrar el estado de las fibras de sustancia blanca mediante Tensor de Difusión . Valorar las diferencias respecto a otras ataxias...
Assessment of Student Learning : A Guidebook for Practice Educators
Creators: name: Ozturk, Ebru
name: Yeung, Janice
name: Dhaliwal, Neelam
name: Fang, Kayla
name: Lau, Gilly
name: Mira, Aileen
name: Taheri, Asal
name: Tchen, Paulo
Publisher: name: The University of British Columbia
Year: 2019

Abstract
The effect of visual cues on auditory stream segregation in musicians and non-musicians
Creators: name: Marozeau, Jeremy
name: Innes-Brown, Hamish
name: Grayden, David B.
name: Burkitt, Anthony N.
name: Blamey, Peter J.
Publisher: name: Swinburne
Year: 2024

description: Background: The ability to separate two interleaved melodies is an important factor in music appreciation. This ability is greatly reduced in people with hearing impairment, contributing to difficulties in music appreciation. The aim of this study was to assess whether visual cues, musical training or musical context could have an effect on this ability, and potentially improve music appreciation for the hearing impaired. Methods: Musicians (N = 18) and non-musicians (N = 19) were asked to rate the difficulty of segregating a four-note repeating melody from interleaved random distracter notes. Visual cues were provided on half the blocks, and two musical contexts were tested, with the overlap between melody and distracter notes either gradually increasing or decreasing. Conclusions: Visual cues, musical training, and musical context all affected the difficulty of extracting the melody from a background of interleaved random distracter notes. Visual cues were effective in reducing the difficulty of segregating the melody from distracter notes, even in individuals with no musical training. These results are consistent with theories that indicate an important role for central (top-down) processes in auditory streaming mechanisms, and suggest that visual cues may help the hearing-impaired enjoy music.
Supplementary document for Laser microprocessing of metal surfaces using a tightly focused radially polarized beam - 4867456.pdf
Creators: name: Kozawa, Yuichi
name: Sato, Masaki
name: Uesugi, Yuuki
name: Sato, Shunichi
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Classical and Physical Optics

description: Detailed experimental setup and procedure.
Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer
Creators: name: McCann, Katy
name: Von Witzleben, Adrian
name: Thomas, Jaya
name: Wang, Chuan
name: Wood, Oliver
name: Singh, Divya
name: Boukas, Konstantinos
name: Bendjama, Kaidre
name: Silvestre, Nathalie
name: Nielsen, Finn Cilius
name: Thomas, Gareth
name: Sanchez-Elsner, Tilman
name: Greenbaum, Jason
name: Schoenberger, Stephen
name: Peters, Bjoern
name: Vijayanand, Pandurangan
name: Savelyeva, Natalia
name: Ottensmeier, Christian
Publisher: name: Universität Ulm
Year: 2022
Subjects: subject: DDC 610 / Medicine & health
subject: Immunogenicity, Vaccine
subject: Lung neoplasms
subject: Lymphocytes, Tumor-infiltrating
subject: T-Lymphocytes
subject: Immungenetik
subject: Lungenkrebs
subject: Impfstoff
subject: T-Lymphozyt

description: BackgroundCancer is characterized by an accumulation of somatic mutations, of which a significant subset can generate cancer-specific neoepitopes that are recognized by autologous T cells. Such neoepitopes are emerging as important targets for cancer immunotherapy, including personalized cancer vaccination strategies.MethodsWe used whole-exome and RNA sequencing analysis to identify potential neoantigens for a patient with non-small cell lung cancer. Thereafter, we assessed the autologous T-cell reactivity to the candidate neoantigens using a long peptide approach in a cultured interferon gamma ELISpot and tracked the neoantigen-specific T-cells in the tumor by T-cell receptor (TCR) sequencing. In parallel, identified gene variants were incorporated into a Modified Vaccinia Ankara-based vaccine, which was evaluated in the human leucocyte antigen A*0201 transgenic mouse model (HHD).ResultsSequencing revealed a tumor with a low mutational burden: 2219 sequence variants were identified from the primary tumor, of which 23 were expressed in the transcriptome, involving 18 gene products. We could demonstrate spontaneous T-cell responses to 5/18 (28%) mutated gene variants, and further analysis of the TCR repertoire of neoantigen-specific CD4+ and CD8+ T cells revealed TCR clonotypes that were expanded in both blood and tumor tissue. Following vaccination of HHD mice, de novo T-cell responses were generated to 4/18 (22%) mutated gene variants; T cells reactive against two variants were also evident in the autologous setting. Subsequently, we determined the major histocompatibility complex restriction of the T-cell responses and used in silico prediction tools to determine the likely neoepitopes.ConclusionsOur study demonstrates the feasibility of efficiently identifying tumor-specific neoantigens that can be targeted by vaccination in tumors with a low mutational burden, promising successful clinical exploitation, with trials currently underway.
title: Diagnóstico diferencial de la patología de la órbita
Creators: name: Moral Cano, Martín
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: CT
subject: MR
subject: Eyes

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Conocer las distintas lesiones que se localizan en la órbita,
sus principales características radiológicas y los puntos clave que permiten realizar el diagnóstico diferencial. Presentar una serie de casos clínicos de nuestro hospital,
en la que...
title: Transcendencia de la TC multidetector en la detección y programación del tratamiento endovascular del pseudoaneurisma aórtico traumático
Creators: name: Martínez Moya, Manuel
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Trauma
subject: Aneurysms
subject: Acute
subject: Stents
subject: Computer Applications-3D
subject: CT-Angiography
subject: Catheter arteriography
subject: Thorax
subject: Arteries / Aorta

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Conocer los datos básicos que deben figurar en todo informe de Urgencias de pacientes con pseudoaneurisma aórtico traumatico de cara a un posterior e inmediato tratamiento endovascular mediante prótesis...
COVID-19 Chain Breaker Through Enhanced Movement Control Order in Selangor
Creators: name: Pangie Anak Bakit
name: Hadita Binti Sapari
name: Hairusnizan Binti Hamzah
name: Nor Hayati Binti Ibrahim
name: Aniz Nor Sofea Binti Muhamed
name: Kadir, Muhammad Akram Bin Abd
name: Hadi, Mohamad Hafizan Bin Abd
name: Farahana Binti Muhamad Pilus
name: Norfazillah Binti Ab Manan
name: Keong, Wan Ming
name: Shukor, Abdullah Husam Bin A
name: Zailiza Binti Suli
Publisher: name: Zenodo
Year: 2020
Subjects: COVID-19
Coronavirus
Chain
Breaker
Enhanced
Movement Control Order
MCO
Selangor

description: Introduction The COVID-19 pandemic has shaken the world since December 2019. Malaysia was not spared from this unprecedented crisis. The Malaysian government had declared Enhanced Movement Control Order (EMCO) in breaking the chain of COVID-19 transmissions in red zone areas in Hulu Langat, Selangor. For the EMCO, Hulu Langat District Health Office (PKDHL) had been responsible to provide the public health responses and measures in the area under the purview of Selangor State Health Department. The Hulu Langat District Health Officer who is a public health specialist led the taskforce for the planning, monitoring and implementing the public health activities while providing the medical services to the people. In this study, we aimed to identify the epidemiological characteristics of COVID-19 in Kampung Sungai Lui, Hulu Langat and the role of EMCO as a chain breaker for COVID-19. Methods A retrospective cross-sectional study was done from March 30, 2020, until May 5, 2020, in the EMCO area in Kampung Sungai Lui, Hulu Langat. This study site was purposely selected due to a sudden surge of positive cases in the area that requires fast and critical public health measures. We collected primary data through Active Case Detection (ACD) and Passive Case Detection (PCD) and the 1,989 population was screened. The epidemiological characteristics and clinical manifestations were analysed using Microsoft Excel 2018 Software. Results [Refer to Poster]. Conclusion A responsive public health measures with comprehensive early detection and adherence of Standard Operating Procedure (SOP) play a pivotal role in breaking the transmission chain of fast-spreading COVID-19 clusters. Epidemiological characterisation of COVID-19 confirmed cases, provides the basis in the development of effective control strategies.
Bats-inspired frequency hopping for mitigation of interference between automotive radars
Creators: name: Bechter, Jonathan
name: Sippel, Carmen
name: Waldschmidt, Christian
Publisher: name: Universität Ulm
Year: 2016
Subjects: subject: DDC 620 / Engineering & allied operations
subject: Radar; Interference
subject: Radarortung
subject: Interferenz

description: It was reported for specific bats, that they use a certain scheme to shift the frequencies of their echo location calls to counteract interferences with conspecifics. As in road traffic, an increasing number of cars is equipped with radar sensors, there is also the problem of mutual interference. The available frequency bands are limited, so a randomized frequency hopping will not be the best solution. In this paper, we adapt the frequency hopping behavior of the bats reported in [1] to a radar system. We discuss the algorithm and show measurements of its performance in an anechoic chamber.
title: Imagen de la epilepsia
Creators: name: Cortes Vela, Jesus
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar y exponer el papel de la neuroimagen estructural en la evaluación de los pacientes con crisis epilépticas. Presentar las lesiones epileptogénicas más comunes encontradas en las pruebas de neuroimagen realizadas a los pacientes con crisis...
title: Patología carotídea no arteriosclerótica: Revisión de los principales hallazgos de imagen y opciones de tratamiento
Creators: name: Rubio Hervás, Carlos
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Neuroradiology brain
subject: Arteries / Aorta
subject: Head and neck
subject: Ultrasound-Colour Doppler
subject: CT-Angiography
subject: Catheter arteriography
subject: Embolisation
subject: Catheters
subject: Aneurysms
subject: Dissection
subject: Fistula

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Revisar la patología carotídea no arteriosclerótica extracraneal. Describir los hallazgos de imagen característicos y valorar la eficacia de la ecografía,
TC,
RM y arteriografía para su...
Neoponera rostrata
Creators: name: Arredondo, Brandon S.
name: Carreño-Guevara, Yennifer
name: Gutierrez-Villanueva, Yenifer
name: Duran-Bautista, Ervin Humprey
name: Gamboa-Tabares, Jean
name: Guerrero, Roberto J.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Neoponera
Neoponera rostrata

description: Neoponera rostrata (Emery, 1890)
Distribution
Amazonas, Caquetá (Fernández et al. 2019).
description: Published as part of Arredondo, Brandon S., Carreño-Guevara, Yennifer, Gutierrez-Villanueva, Yenifer, Duran-Bautista, Ervin Humprey, Gamboa-Tabares, Jean & Guerrero, Roberto J., 2025, Soil and leaf litter ants from the Amazon Region offer new distribution records for Colombia, pp. e 142813 in Biodiversity Data Journal 13 on page e142813, DOI: 10.3897/BDJ.13.e142813
Supplementary document for Laser microprocessing of metal surfaces using a tightly focused radially polarized beam - 4867456.pdf
Creators: name: Kozawa, Yuichi
name: Sato, Masaki
name: Uesugi, Yuuki
name: Sato, Shunichi
Publisher: name: Optica Publishing Group
Year: 2020
Subjects: Classical and Physical Optics

description: Detailed experimental setup and procedure.
Surfactant-mediated biodegradation of polycyclic aromatic hydrocarbons
Creators: name: Li, Jing-Liang
name: Chen, Bing-Hung
Publisher: name: Swinburne
Year: 2024

description: Polycyclic aromatic hydrocarbons (PAHs) are toxic environmental pollutants that are known or suspected carcinogens or mutagens. Bioremediation has been used as a general way to eliminate them from the contaminated sites or aquifers, but their biodegradation is rather limited due to their low bioavailability because of their sparingly soluble nature. Surfactant-mediated biodegradation is a promising alternative. The presence of surfactants can increase the solubility of PAHs and hence potentially increase their bioavailability. However, inconclusive results have been reported on the effects of surfactant on the biodegradation of PAHs. In this work, surfactant-mediated biodegradation of PAHs is reviewed.
Neoponera striatinodis
Creators: name: Arredondo, Brandon S.
name: Carreño-Guevara, Yennifer
name: Gutierrez-Villanueva, Yenifer
name: Duran-Bautista, Ervin Humprey
name: Gamboa-Tabares, Jean
name: Guerrero, Roberto J.
Publisher: name: Zenodo
Year: 2025
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Formicidae
Neoponera
Neoponera striatinodis

description: Neoponera striatinodis (Emery, 1890)
Distribution
Antioquia, Caquetá, Cauca, Chocó, Meta, Putumayo, Valle del Cauca (Chacón de Ulloa et al. 2012, Fernández et al. 2019).
description: Published as part of Arredondo, Brandon S., Carreño-Guevara, Yennifer, Gutierrez-Villanueva, Yenifer, Duran-Bautista, Ervin Humprey, Gamboa-Tabares, Jean & Guerrero, Roberto J., 2025, Soil and leaf litter ants from the Amazon Region offer new distribution records for Colombia, pp. e 142813 in Biodiversity Data Journal 13 on page e142813, DOI: 10.3897/BDJ.13.e142813
title: Virtopsia: Una nueva herramienta para la Medicina Forence.
Creators: name: Gonzalez Alvarado, Guillermo Alejandro
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Forensics
subject: Experimental investigations
subject: Computer Applications-Virtual imaging
subject: Outcomes analysis
subject: CT-High Resolution
subject: Forensic / Necropsy studies

description: Objetivos
Material y método
Resultados
Conclusiones
description: Objetivos:
Los estudios por imágenes representan una gran herramienta para la medicina forense,
cada vez son más los casos en que es necesaria la aplicación de este tipo de tecnología en el campo de la ciencia forense. Surgen grandes complicaciones a la...
The search for new catalysts for Ziegler-Natta olefin polymerization: Exploratory studies in unusual direction
Creators: name: Enright, Dave S
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Chemistry, Inorganic.

description: The preparation of two tetravalent d2 chromium alkyls is revisited. Their ability to work both as starting materials for further functionalization and as Ziegler-Natta catalysts is investigated. The clarification of the reaction pathway through which a trivalent chromium salt may form a homoleptic tetravalent derivative is also considered. Finally, the elucidation of the nature of the Cr-Cr interaction in a unique [R2Cr] 4 tetranuclear cluster and evaluation of its stability is undertaken. This is followed by a reassessment of the stability of tetravalent vanadium alkyls. Wilkinson first reported, in the seventies, the preparation of homoleptic R4V species [R = C6H5, CH2Si(CH 3)3]. The full characterisation of a homoleptic R4V, by crystal structure, and testing the catalytic activity is reported. The alpha,alpha-diiminopyridine ligand {alpha,alpha' -[2,6-(i-Pr)2PhN=C(Me)]2(C 5H3N)} has recently attracted considerable attention because of its ability to form highly active polymerization catalysts. Recent work from this research group and others has shown that this alpha,alpha '-diiminopyridine ligand can be involved in the organometallic transformations of the metal center. The ability of the ligand to accept or to donate negative charge to the metal is central to the fine tuning of the redox potential of the metal, and of its Lewis acidity that in turn determines the catalytic behaviour. A clarification for the ability of this remarkable ligand system to accept negative charge is offered. Reductions of {alpha,alpha'-[2,6-(i-Pr) 2PhN=C(Me)]2(C5H3N)} with strong reductants such as Li and Li(naftalenide) and in the absence of transition metals were carried out to yield rare case trilithium organyls.
Supplementary document for Optical phased array beam steering in the mid-infrared on an InP-based platform - 4868722.pdf
Creators: name: Midkiff, Jason
name: Yoo, Kyoung Min
name: Shin, Jong-Dug
name: Dalir, Hamed
name: Teimourpour, Mohammad Hosain
name: Chen, Ray
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: Supplement 1
title: Complicaciones de las fracturas de tobillo: manejo y hallazgos en imagen.
Creators: name: Aleman Navarro, Carmen Maria
Publisher: name: Sociedad Española de Radiología Médica
Year: 2012
Subjects: subject: Musculoskeletal bone
subject: CT
subject: MR
subject: Surgery

description: Objetivo docente
Revisión del tema
Conclusiones
description: Objetivo docente:
Conocer la prevalencia,
el mecanismo de acción y los tipos de fracturas más frecuentes del tobillo. Establecer las técnicas de imagen más adecuadas para el seguimiento de los pacientes operados. Describir los patrones radiológicos con Rx,
TC y...
BC Wine Territory Identity
Creators: name: Buschert, Kim
name: Mooken, Malida
name: Pesme, Jacques-Olivier
name: Sugden, Roger
name: Valania, Marcela
Publisher: name: The University of British Columbia
Year: 2019

description: The Okanagan campus of the University of British Columbia (UBC) and KEDGE Business School, Bordeaux, have been working with the British Columbia wine industry to develop its sense of identity for a number of years. More recently, we have partnered with the Innovation School at the Glasgow School of Art (GSA) to create and deliver participatory workshops in November 2017, and we included a full-day workshop on identity as part of the 2018 Wine Leaders Forum. These workshops stimulated thinking about aspects of identity, including terroir, authenticity, expression, and the overall narrative presented by the BC wine territory. This report outlines our activities to date, introduces the idea of identity, discusses its importance for wine regions, analyzes findings, recommends actions for wineries, growers, industry organizations and regional associations, and concludes with our commitment. It complements GSA’s (2018) report of the workshops.
Imagining Canada, imagining Canadians: National identity in English as a second language textbooks
Creators: name: Gulliver, Trevor H
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Canadian Studies.
subject: Education, English as a Second Language.

description: In this study, I establish that language textbooks are sites of discursive struggle through which nationalist imagined communities are reproduced. I use critical discourse analysis to analyze how these textbooks construct Canadian identities that position students in relation to an imagined community of Canada. I analyze twenty-four textbooks and three Citizenship and Immigration Canada publications used in government-funded language instruction in Ontario. Representations of Canada and Canadianness in the texts examined include and exclude student readers, participate in banal nationalism, and legitimate particular understandings of Canada. The identified textbooks mark nationality through flags, maps, references to nation, and the use of nation as a frame of reference. The textbooks also make claims about how 'Canadians' think and behave. This banal nationalism naturalizes and essentializes imaginings of 'Canada' and 'Canadianness' supporting particular and interested constructions and positive evaluations of 'Canadian' identity. Both government produced publications and identified textbooks legitimate constructions of Canadian identity through repeated positive representations of Canadianness; the marginalising inclusions of 'others'; the subordination of gendered, racialised, and classed social positions to nation; and by maintaining a low level of dialogicality overall.
Public Health Measures in Managing COVID-19 At Seksyen 6 Bandar Baru Bangi
Creators: name: Aniz Nor Sofia Mohamed
name: Norfazillah Binti Ab Manan
name: Hadita Binti Sapari
name: Kadir, Muhammad Akram Bin Abd
name: Hafizan Abd Hadi
name: Farahana Binti Muhammad Pilus
name: Keong, Wan Ming
name: Shukor, Abdullah Husam Bin A
name: Sulli, Zailiza Binti
Publisher: name: Zenodo
Year: 2020
Subjects: Public Health
Measures
Managing
COVID-19
Coronavirus
Bandar Baru Bangi
Seksyen 6

description: Introduction COVID-19 is an infectious disease caused by a novel coronavirus, a type of virus known to cause respiratory infections in humans. It cause a significant threat to public health. Hulu Langat District Health Office has the highest number of confirmed cases of COVID-19 in Selangor. Until 15th August 2020, Hulu Langat District Health Office received 20,500 notifications with 634 confirmed cases. Two notifications of positive COVID-19 infection were received by Hulu Langat District Heath Office on 20th March 2020. Subsequently, Rapid Assesment Team (RAT) and Rapid Response Team (RRT) was mobilized to investigate the outbreak and implementing a control measure. The objective of this study is to describe sociodemographic characteristic ans public health measures for a cluster in Seksyen 6 Bandar Baru Bangi. Material and Methods A retrospective cross-sectional study was carried out. Data from Active Case Detection and Passive Case Detection was collected from 20th March 2020 - 16th May 2020 which involves all positive COVID-19 cases in Puncak Bangi and Bangi Lake Villa that were tested with RT PCR. Demographic, risk factors, clinical manifestations, were analysed using SPSS Version 25. Results [Refer to Poster]. Discussion Rapid interagency collaboration in response has significantly helps in breaking the chain of transmission Seksyen 6 Bandar Baru Bangi. Public health measures were effective that no further cases notified after two incubation period.
Understanding the Context, Impacts and Consequences of Accreditation on Canadian University Business Schools
Creators: name: Elliott, Catherine J
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Education, Business.
subject: Education, Higher.

description: Accreditation by the Association to Advance Collegiate Schools of Business (AACSB International) and its impact on Canadian university business schools (UBSs) is a question that has been studied empirically in only a limited manner in recent years. The purpose of this study was to explore the potential consequences as perceived by administrators and faculty members. Does accreditation constrain organizational actions, or conversely, does it facilitate organizational learning? What are the contextual factors which influence these potential consequences? A qualitative, multiple case study approach was employed to study these questions. A sample of four business schools was selected; and data were collected from multiple sources. In Phase I, data was analyzed using NVivo7 and individual case profiles were prepared. These were validated and provided input into Phase II in which a multiple case analysis was performed. Emergent themes were identified and informed by three main bodies of knowledge: accreditation, institutional theory, and evaluation for organizational learning. The study concluded that the primary drivers for seeking accreditation by Canadian UBSs were marketing-related - accreditation was seen as a powerful marketing tool which could be used in a highly uncertain and competitive market to enhance reputation and gain competitive advantage. Primarily motivated by the Dean/Director, accreditation was seen as a lever for change, both within the school and with central administration. Perceived impacts were related to these drivers - enhanced reputation, leverage for change, management efficiencies, an increased focus on research and quality, and program changes. Five contextual factors were found to be potent in influencing the drivers, impacts and consequences of accreditation, with leadership being the most pervasive. In terms of the enabling or constraining consequences, AACSB accreditation was perceived to be slightly enabling or neutral in its effect. While accreditation did promote some elements of organizational learning in three of the four schools, (continuous improvement), the learning effects were limited in scope, duration, and magnitude. There was insufficient evidence to suggest that double loop learning had occurred. Although accreditation was viewed to be constraining in several ways, overall it was not perceived to be overly restrictive.