cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Understanding the Dynamics of Nascent Entrepreneurship-Prestart-Up Experience, Intentions, and Entrepreneurial Success
Creators: name: Hopp, Christian
name: Sonderegger, Rolf
Publisher: name: Wiley
Year: 2014

description: Understanding the factors driving the successful founding of new firms is a subject of ongoing interest. We link prestart‐up experience and intentions of nascent entrepreneurs to the shape of the entrepreneurial gestation process and eventually to successful founding. By experience, we mean previous entrepreneurial activities, labor market experience, and formal education, and by intentions, we mean commitment and ability expectations. We test our predictions on a longitudinal data set that tracks nascent entrepreneurs' venture creation efforts over a five‐year time span and find evidence supporting them. Against this background, our findings also show that when controlling for the possible endogeneity of the activities carried out, a later temporal concentration of organizing activities enhances the probability of successfully founding. Our research contributes to a better understanding of contextual antecedents of the shape of gestation process and the way experience and intentions affect the successful creation of new ventures. Implications for theory and practice are discussed.
Wald, Steinschlagschutznetz oder beides? Ein risikobasierter Vergleich unter Einbezug von Störungen
Creators: name: Moos, Christine
name: Thomas, Mélanie
name: Pauli, Bernhard
name: Dorren, Luuk
Publisher: name: Schweizerischer Forstverein
Year: 2020
Subjects: protection forest
natural hazard
rockfall net
wildfire disturbance
risk analysis
net present value

description: Dank Schutzwäldern können in der Schweiz an vielen Orten die Kosten für technische Schutzmassnahmen re-duziert oder vermieden werden. Um finanzielle Mittel im Schutzwald- und Naturgefahrenmanagement mög-lichst effizient einsetzen zu können, ist eine realistische Quantifizierung der langfristigen Schutzwirkung wich-tig. Das Ziel dieser Studie ist es, den Kapitalwert eines Steinschlagschutzwaldes in Mendrisio (TI) zu ermitteln und mit dem Kapitalwert von Steinschlagschutznetzen sowie einer Kombination der beiden Massnahmen zu vergleichen. Dabei soll die zeitliche Variabilität in der Schutzwirkung des Waldes aufgrund von Störungen mit-einbezogen werden. Die in der Analyse berücksichtigten Kosten sind Holzerntekosten sowie Investitions- und Unterhaltskosten für die Steinschlagschutznetze. Der angenommene Nutzen setzt sich aus der monetarisierten Risikoreduktion einer Schutzmassnahme sowie aus den generierten Holzerlösen zusammen. Unsicherheiten im Hinblick auf die dauerhafte Gewährleistung der Schutzwirkung – beispielsweise einer Abnahme aufgrund von möglichen Waldbränden – werden mittels eines probabilistischen Ansatzes über einen Zeitraum von 100 Jah-ren simuliert. Sowohl der Schutzwald als auch die Netze reduzieren das Steinschlagrisiko um etwa 75% für das betrachtete Untersuchungsgebiet. Der Kapitalwert der Schutzwaldbewirtschaftung ist positiv, wohingegen die permanenten Schutznetze einen deutlich negativen Kapitalwert haben. Dies impliziert, dass die zusätzliche Schutzwirkung der Netze zum Schutzwald die sehr hohen Investitionskosten nicht kompensieren kann. Die Va-riation im Kapitalwert aufgrund möglicher Waldbrände ist gering. Temporäre Netze können die vorübergehende Reduktion der Schutzwirkung nach einem grösseren Waldbrand kompensieren. Ihr Kapitalwert ist jedoch wie-derum niedriger verglichen mit der Situation ohne Netz. Die in der vorliegenden Studie präsentierte Methode erlaubt eine realistische Bewertung der Schutzwaldwirkung und hilft, optimale Kombinationen von Schutzmass-nahmen zu finden.
Umsetzung problemloser als angenommen : Sabine Hahn im Gespräch mit Brigitte Wüthrich.
Creators: name: Hahn, Sabine
Publisher: name: Hogrefe
Year: 2017

description: Brigitte Wüthrich arbeitet seit 1985 als diplomierte Pﬂ egefachfrau Psychiatrie. Heute ist sie Leiterin Pﬂ ege im Domicil Mon Bijou in Bern, einer Pﬂ egeeinrichtung für betagte Menschen, die beim eigenständigen Leben und Wohnen Unterstützung brauchen.
Dietro le quinte: il Teatro Sociale di Feltre nell'Ottocento
Creators: name: Brunello, Giulia
Year: 2022

description: All'interno del panel “Storia dell’Arte e dell’Architettura”, la relazione è un’occasione per riflettere su come fonti storico-archivistiche di insolita ricchezza possano essere utilizzate nella valorizzazione del patrimonio culturale di una città. La ricerca indaga la storia dell’edificio, la sua amministrazione, il materiale scenico, il repertorio del teatro nel corso dell’Ottocento, l’organizzazione e la programmazione degli spettacoli (quindi il ruolo della direzione, di impresari,, compagnie). In questa occasione verranno sottolineati gli elementi che possono portare un contributo allo discussione sul valore della collaborazione tra pubblico e privato e sull’importanza dell’unione di competenze nella valorizzazione di un edifico storico.
Fermentation for Microbial Biomass
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Creative Biogene can help you with commercial probiotics biomanufacturing and packaging in different dosage forms, including capsules, tablets, powders and liquids. Fermented foods contain specific probiotic strains at a suitable level and thus have antioxidant properties, immunomodulatory, antithrombic, and antihypertensive properties. We can also provide custom fermentation services to improve food taste, flavor, nutrients through utilizing specific probiotics.
Cyperus esculentus L.
Creators: name: Info Flora
Publisher: name: Zenodo
Year: 2021
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Liliopsida
Poales
Cyperaceae
Cyperus
Cyperus esculentus

description: Cyperus esculentus L.
Essbares Zypergras
Art ISFS: 129660 Checklist: 1014370 Cyperaceae Cyperus Cyperus esculentus L.
Bestimmungsschlüssel
Zusammenfassung
Artbeschreibung (nach Lauber & al. 2018): 10-50(-90) cm hoch, kräftig, unten beblättert, scharf 3kantig. Blätter hellgrün, steif, 5-10 mm breit. Blütenstand mit 4-10 Ästen, diese bis 15 cm lang, an der Spitze die 6-12 mm langen, bräunlichen oder gelblichen Ährchen tragend. Ährchenachse geflügelt. Blütenstand von 2-9 Hochblättern teilweise überragt. Narben 3. Tragblätter am Rücken gerundet. Frucht halb so lang wie diese, dunkelgrau oder rötlich. Essbar sind die 1-2 cm langen Wurzelknöllchen.
Blütezeit (nach Lauber & al. 2018): 7-10
Standort und Verbreitung in der Schweiz (nach Lauber & al. 2018): Gräben, Teiche, Kulturen / kollin / TI, M, vereinzelt AN
Verbreitung global (nach Lauber & al. 2018): Weltweit verbreitet
Ökologische Zeigerwerte (nach Landolt & al. 2010) 4w + 33-452.g.2n=(108)208
Ökologie
Lebensform Geophyt
Lebensraum Lebensraumnach Delarze & al. 2015
2.5.2 - Mehrjährige Schlammflur (Zweizahnflur) (Bidention)8.2.3.1 - Kalkarmer, lehmiger Hackfruchtacker (Polygono-Chenopodion)
fett Dominante Art, welche das Aussehen des Lebensraumes mitprägt Charakterart Weniger strikt an den Lebensraum gebundene Art
Ökologische Zeigerwerte nach Landolt & al. (2010)
BodenfaktorenKlimafaktorenSalztoleranzFeuchtezahl Fsehr feucht; Feuchtigkeit stark wechselnd (mehr als ± 2 Stufen)Lichtzahl LhellSalzzeichen--Reaktionszahl Rschwach sauer bis neutral (pH 4.5-7.5)Temperaturzahl Tsehr warm-kollin (nur an wärmsten Stellen, Hauptverbreitung in Südeuropa)Nährstoffzahl Nmässig nährstoffarm bis mässig nährstoffreichKontinentalitätszahl Ksubozeanisch (hohe Luftfeuchtigkeit, geringe Temperaturschwankungen, eher milde Winter)
Nomenklatur
Gültiger Name (Checklist 2017):Cyperus esculentusL.
Volksname Deutscher Name: Essbares Zypergras, Erdmandel Nom français: Souchet comestible Nome italiano: Zigolo dolce
Übereinstimmung mit anderen Referenzwerken
RelationNomReferenzwerkeNo=Cyperus esculentus L.Checklist 2017129660=Cyperus esculentus L.Flora Helvetica 20012472=Cyperus esculentus L.Flora Helvetica 20122648=Cyperus esculentus L.Flora Helvetica 20182648=Cyperus esculentus L.Index synonymique 1996129660=Cyperus esculentus L.SISF/ISFS 2129660
= Taxon stimmt mit akzeptiertem Taxon überein (Checklist 2017)  Taxon enthält (neben anderen) auch das akzeptierte Taxon (Checklist 2017)
Status Indigenat: Neophyt: nach der Entdeckung von Amerika in der Region aufgetreten (nach 1500)
Liste der gefährdeten Pflanzen IUCN(nach Walter & Gillett 1997): NeinArt der "Liste der potenziell invasiven gebietsfremden Arten"Neophyten-Infoblatt
description: Published as part of Info Flora, 2021,
Microbial Community Analysis Platform
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Creative Biogene offers state-of-the-art microbial community analysis services. The microbial community analysis offer the opportunity to discover the information on the entire set of microorganisms (bacteria, yeasts, fungi, algae, etc.) present in a given sample. And improve the microbial diversity studies for environmental (e.g. food, water and soil) and other microbial samples (e.g. gut microbiome or skin microbiome).
Microbial Fermentation
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2023

description: With the rapid development of genomics, metabolomics and proteomics, microbial fermentation offers tremendous potential to heal, feed, bio-agriculture and bio-energy. We, Creative Biogene, have had extensive experience in the development and manufacturing of finished formulations and APIs for pharmaceutical products, pesticides, veterinary medicines and industrial enzymes by using microorganisms.
Arbeitslosenversicherung: gleiche Regeln, unterschiedlicher Schutz
Creators: name: Hevenstone, Debra
name: Kessler, Dorian
name: Kuhn, Ursina
Publisher: name: Berner Fachhochschule, Soziale Arbeit
Year: 2022

description: Bei einem Stellenverlust sind die Betroffenen je nach Haushaltsform und Familienmodell unterschiedlich stark auf staatliche Unterstützung angewiesen. Das Projekt «Familienmodelle und Arbeitslosigkeit» zeigt auf, wie sich die Wirkung von Arbeitslosentaggeldern unterscheidet und wie die Wirksamkeit der Arbeitslosenversicherung gesteigert werden könnte.
Adenovirus Service
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: The genome of adenovirus is a linear, non-segmented double-stranded (ds) DNA that is between 26000 and 48000 bp containing 22-46 protein-coding genes. The genes are divided into early phase (including E1, E2, E3, E4) and late phase (including L1, L2, L3, L4 and L5). Adenoviruses have a broad range of hosts and several adenoviral serotypes have been found, for example, there are 57 human adenovirus serotypes (HAdV-1 to 57) in seven species (Human adenovirus A to G).
GPCR Stable Cell Line Development
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: With years of experience and thousands of accomplished projects, Creative Biogene offers flexible GPCR detection solutions which can help customer to achieve an ideal GPCR stable cell line suitable for downstream cell-based assay. We can generate stable cell lines used to measure GPCR signaling through second messenger, arrestin recruitment, and internalization readouts.
Nestbox design influences territory occupancy and reproduction in a declining, secondary cavity-breeding bird
Creators: name: Zingg, Silvia
name: Arlettaz, Raphaël
name: Schaub, Michael
Publisher: name: Nederlandse Ornithologische Unie
Year: 2010

description: Nestboxes are a popular measure to support populations of endangered secondary-cavity breeding birds. Yet, studies of the impact of nestbox abundance and design on bird breeding ecology in intensive farmland remain scarce, We experimentally studied nestbox preferences in a Wryneck Jynx torquilla population in SW Switzerland. Initially designed for the larger Hoopoe Upupa epops, voluminous nestboxes installed at 269 locations within the study area were checked for Wryneck breeding since 2002. In 2008, we installed smaller sized, Wryneck compatible nestboxes at 135 locations (50%) randomly selected from these 269 locations. We recorded the nestbox design preferences of Wrynecks, and measured reproductive output, nestling body mass and tarsus length, while assessing patterns of intra- and interspecific competition. Wrynecks settled in territories equipped with the more suitably designed nestboxes more than expected by chance and preferentially used them for raising their broods. The number of fledged young did not depend on nestbox design, although nestlings were slightly heavier in the smaller nestboxes, probably due to reduced interspecific competition with Hoopoes. This study shows that in particular territory attractiveness can be enhanced when artificial cavities with an appropriate design are provided. Nestbox provisioning is an efficient conservation measure for endangered bird species but attention should be paid to nestbox design which has to be tailored to species-specific requirements.
MOESM5 of Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticityÂ by HDAC inhibitors
Creators: name: Lennartsson, Andreas
name: Arner, Erik
name: Fagiolini, Michela
name: Saxena, Alka
name: Andersson, Robin
name: Hazuki Takahashi
name: Noro, Yukihiko
name: Sng, Judy
name: Sandelin, Albin
name: Hensch, Takao
name: Carninci, Piero
Publisher: name: Figshare
Year: 2015
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 5: Figure S2. VPA-induced FoxG1 expression with binding sites which overlap VPA-induced DHSS. (A) Genome browser view for the Foxg1 locus. CAGE tags are significantly upregulated in the VPA sample compared to vehicle, at a start site downstream of the canonical RefSeq TSS, corresponding to previously described transcript BC064449. (B) Comparison between the Foxg1 binding motif and the Foxa2 motif. (C) qPCR validation for induced FoxG1 expression after 2Â h VPA treatment.
Verfahren der multivariaten Statistik zur Beurteilung der Resultate und der Zuverlässigkeit geodätischer Messsysteme
Creators: name: Carosio, Alessandro
Publisher: name: ETH Zurich
Year: 1983
Subjects: MULTIVARIATE METHODEN (MATHEMATISCHE STATISTIK)
GEODÄTISCHE INSTRUMENTE UND GERÄTE (GEODÄSIE)
ZUVERLÄSSIGKEIT (INGENIEURWESEN)
MULTIVARIATE METHODS (MATHEMATICAL STATISTICS)
GEODETIC INSTRUMENTS AND EQUIPMENT (GEODESY)
RELIABILITY (ENGINEERING)
info:eu-repo/classification/ddc/550
Earth sciences

description: Mitteilungen / Institut für Geodäsie und Photogrammetrie an der Eidgenössischen Technischen Hochschule Zürich, 35
Tn5 Transposase
Creators: name: Cole, Hannah
Publisher: name: Zenodo
Year: 2023

description: Transposase (Tnp) Tn5 is a member of the RNase superfamily of proteins which includes retroviral integrases. Tn5 can be found in Shewanella and Escherichia bacteria. The transposon codes for antibiotic resistance to kanamycin and other aminoglycoside antibiotics. Transposition works through a "cut-and-paste" mechanism, where the Tn5 excises itself from the donor DNA and inserts into a target sequence, creating a 9-bp duplication of the target.
Sensorik im Gesundheitswesen: Sensordaten und Algorithmen (Teil 2)
Creators: name: Buri, Marco Viktor Franz-Josef
name: Burch, Selina Noemi
name: Bruhin, Lena
name: Thilo, Friederike J.S.
Publisher: name: Berner Fachhochschule, Wirtschaft
Year: 2023

description: Ältere Menschen bewegen sich oft unsicher und können leicht stürzen und sich verletzen. Damit dies verhindert werden kann, könnten Sensoren Bewegungsmuster aufzeichnen, analysieren und vor Risiken warnen. Dies untersuchen Forscher*innen im Innovationsfeld Digitale Gesundheit der Berner Fachhochschule. Im 1. Teil ging es um Chancen und Herausforderungen der Technologie, in diesem 2. Teil liefert das Forscherteam einen Blick in den praktischen Einsatz.
Datenstrukturen für Landinformationssysteme: semantische, topologische und räumliche Beziehungen in Daten der Geo-Wissenschaften
Creators: name: Frank, André
Publisher: name: ETH Zurich
Year: 1983
Subjects: LANDINFORMATIONSSYSTEME (KARTOGRAPHIE)
LAND INFORMATION SYSTEMS (CARTOGRAPHY)
info:eu-repo/classification/ddc/550
Earth sciences

description: Mitteilungen / Institut für Geodäsie und Photogrammetrie an der Eidgenössischen Technischen Hochschule Zürich, 34
Genome Editing in Plant
Creators: name: Cole, Hannah
Publisher: name: Zenodo
Year: 2023

description: Microorganisms serve to ferment foods, decompose wastes, treat sewage, produce metabolites, fuel, enzymes and other bioactive compounds. Manipulation of genomic sequences facilitates the identification and characterization of key genetic determinants in the investigation of biological processes. Creative Biogene has the capacity to specifically modify microbial genomes in an efficient and precise way. With talented staffs, advanced technologies and state-of-the-art facilities, Creative Biogene provides microbial genome editing service, including traditional recombineering system, CRISPR/Cas 9 system and site-specific recombination system.
Custom Viral Service
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Creative Biogene provides world-class custom viral service for a variety of viral types using our QVirusTM platform. Creative Biogene's state-of-the-art facilities and highly experienced staff are available in order to assist in all areas of virus vector design and construction, as well as the generation of the virus in a quick turnaround. Our custom viral services are highlighted by a consistent high titer and large delivery viral counts.
gene editing cell line generation
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: CRISPR as a highly efficient gene editing tool can manipulate the genome of a cell to achieve gene knockout, knock-in, targeted gene mutation in specific cells. Gene-edited cell lines generated by CRISPR/Cas9 technology can be widely used for gene function research, signaling, recombinant protein preparation, drug discovery, and disease mechanism of action research. Creative Biogene's scientists utilize advanced CRISPR technology to efficiently and precisely modify specific genes in a variety of cell types, including but not limited to mammalian cells, stem cells, and other cells, based on the research needs of our clients. We are committed to providing comprehensive and efficient gene editing cell line generation services to accelerate your research.
Additional file 1: Supplementary Tables. of Whole-body patterns of the range of joint motion in young adults: masculine type and feminine type
Creators: name: Moromizato, Keiichi
name: Kimura, Ryosuke
name: Fukase, Hitoshi
name: Yamaguchi, Kyoko
name: Ishida, Hajime
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy

description: Table S1. Age, hand/arm and foot/leg dominances, and experience of sports of the subjects dominances of the subjects. Table S2. Somatometric and sthenometric measurements in the subjects. (DOCX 23 kb)
Drug-Resistant Cell Model Generation
Creators: name: Cole, Hannah
Publisher: name: Zenodo
Year: 2023

description: Drug-resistant cell models are needed to investigate the mechanisms underlying drug resistance acquisition in cancer cells in order to develop hypotheses that can be tested by the use of clinical material. Researchers use drug-resistant cell models to mimic the conditions cancer patients experience during chemotherapy, and to understand potential mechanisms of resistance to chemotherapy agents. However, the reference regarding the methodology of the development process is little, and exploring a suitable selection strategy and finally generating stably drug-resistant cell model in house can be very time- and energy- consuming.
Bildung und Sozialhilfe: Paradigmenwechsel mit Hürden
Creators: name: Beyeler, Michelle
name: Schuwey, Claudia
Publisher: name: Berner Fachhochschule, Soziale Arbeit
Year: 2022

description: Der aktuelle Kennzahlenvergleich zur Sozialhilfe in Schweizer Städten legt den Schwerpunkt auf das Thema Bildung von Sozialhilfebeziehenden. Eine Online-Umfrage bei den Sozialdiensten beleuchtet, wie es gelingt Fördermassnahmen umzusetzen, und zeigt bestehende Hindernisse auf.
Microbial Identification
Creators: name: Brady, Marcia
name: Brady, Marcia
Publisher: name: Zenodo
Year: 2023

description: Microbial identification methods include morphological observation, identification of physiological and biochemical characteristics, automatic analysis and identification of BIOLOG carbon source, molecular biology identification, numerical identification of API bacteria, functional analysis and functional gene, RAPD, SSCP, TLC thin layer chromatography, whole cell fatty acid analysis and identification, (G+C) mol% determination, DNA/DNA homology determination, etc.
Baculovirus
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Baculovirus are large double-stranded enveloped viruses consisting of circular DNA genomes. Since 1983, when the baculovirus expression system (BES) technology was first used to express human beta interferon in insect cells, the BES has become a versatile and robust eukaryotic expression system for foreign protein expression. Baculoviruses have several advantages over other expression vector systems.
Microbial Cell-surface Display Service
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Microbial cell surface display technology holds great strategic potential for expressing heterologous proteins or polypeptides with a distinct function on the surface of microbial cells. To gain amenable cell surface exposure, the passenger protein could be fused with various anchoring motifs (carrier protein), which are usually cell-surface proteins or their fragments. Up to the characteristics of passenger and carrier proteins, this strategy can be carried out using different fusion methods, such as C-terminal fusion, N-terminal fusion or sandwich fusion. Creative Biogene provides various cell-surface display systems for the successful display of a target protein or peptide on the surface of bacteria via genetic fusion to anchoring motif.
A comprehensive framework for Hospital@home care models
Creators: name: Denecke, Kerstin
name: Kushniruk, Andre W.
name: Borycki, Elizabeth M.
Publisher: name: IOS Press
Year: 2024
Subjects: Hospital at home Care model Patient at home Innovation Framework

description: Hospital@home is a healthcare approach, where patients receive active treatment from health professionals in their own home for conditions that would normally necessitate a hospital stay. Objective : To develop a framework of relevant features for describing hospital@home care models. Methods : The framework was developed based on a literature review and thematic analysis. We considered 42 papers describing hospital@home care approaches. Extracted features were grouped and aggregated in a framework. Results : The framework consists of nine dimensions: Persons involved, target patient population, service delivery, intended outcome, first point of contact, technology involved, quality, and data collection. The framework provides a comprehensive list of required roles, technologies and service types. Conclusion : The framework can act as a guide for researchers to develop new technologies or interventions to improve hospital@home, particularly in areas such as tele-health, wearable technology, and patient self-management tools. Healthcare providers can use the framework as a guide or blueprint for building or expanding upon their hospital@home services.
Digital Age Organizations: Uncovering Over-the-Air Updates in the Smart Product Realm
Creators: name: Schulz, Colin
name: Raff, Stefan
name: Kortmann, Sebastian
name: Obwegeser, Nikolaus
Publisher: name: AIS
Year: 2021

description: Over-the-air (OTA) updates are gaining traction across various industries such as manufacturing, healthcare, and automotive. However, there is currently no consistent conceptualization of OTA updates in place. Also, we know little about what organizational capabilities are needed to turn OTA updates into customer value and thus infuse digital business models. Against this backdrop, this work follows two goals. First, to conceptually delineate what constitutes OTA updates and second, to pinpoint the organizational capabilities required to successfully manage OTA updates. Building on a large-scale survey of 360 product managers in manufacturing companies, we suggest that organizations follow two strategic steps when building OTA capabilities. First, they build the required technical competence and leverage it through their ability to create new innovative services. Second, performant companies deliver and monetize their value proposition in new ways by refining their business models.
Analytical Testing
Creators: name: Cole, Hannah
Publisher: name: Zenodo
Year: 2023

description: Analytical testing service is a deep analysis of samples through biological, chemical and physical method or with high-tech instruments. Utilizing analytical testing, it is accurate and rapid to find the trace contamination of products, including microbes, virus, adventitious cell and reagents. Contamination is considered as the main problem in manufacturing process of biological and clinic products.
Microbial Genome Editing
Creators: name: Brady, Marica
Publisher: name: Zenodo
Year: 2023

description: Microorganisms serve to ferment foods, decompose wastes, treat sewage, produce metabolites, fuel, enzymes and other bioactive compounds. Manipulation of genomic sequences facilitates the identification and characterization of key genetic determinants in the investigation of biological processes. Creative Biogene has the capacity to specifically modify microbial genomes in an efficient and precise way. With talented staffs, advanced technologies and state-of-the-art facilities, Creative Biogene provides microbial genome editing service, including traditional recombineering system, CRISPR/Cas 9 system and site-specific recombination system.
YouTube and the implementation and discontinuation of the oral contraceptive pill : a mixed-method content analysis
Creators: name: Niemann, Jana-Kristin
name: Wicherski, Lea
name: Glaum, Lisa
name: Schenk, Liane
name: Stadler, Getraud
name: Richter, Matthias
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Women living in high-quality healthcare systems are more likely to use oral contraceptives at some point in their lives. Research findings have sparked controversial discussions about contraception in the scientific community and the media, potentially leading to higher rates of method discontinuation. Understanding the underlying motives for method discontinuation is crucial for reproductive health equity and future programming interventions. To address this question, this study aims to explore women’s experiences of oral contraceptive use and discontinuation on YouTube. Methods: A concurrent explanatory mixed-methods design was used to conduct content analysis of German YouTube videos. The information from 175 videos of 158 individuals was extracted through quantitative descriptive content analysis. Twenty-one individuals were included in the qualitative content analysis. Findings: The body was a recurring theme in the pill biographies. Women described, for example, bodily sensations as reasons for taking and stopping the pill. They also described positive and negative side effects while taking the pill and after stopping. The most common side effects of taking the pill mentioned by YouTubers were mood swings (76/158), weight gain (45/158), headaches (33/158), and depressed mood (45/158). The symptoms after discontinuation reported most were facial skin impurities (108/158), decreased mood swings (47/158), hair loss (42/158), and weight loss (36/158). Overall, women overwhelmingly rated their discontinuation experience as positive (87/91). Conclusions: The study identified key symptoms of oral contraceptive initiation and discontinuation by portraying the experiences of female YouTubers, adding valuable insights to the understanding of method initiation and discontinuation. Further research is needed to explore women’s personal experiences with method discontinuation beyond the YouTube platform.
Microbial Identification
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2023

description: Microbial identification methods include morphological observation, identification of physiological and biochemical characteristics, automatic analysis and identification of BIOLOG carbon source, molecular biology identification, numerical identification of API bacteria, functional analysis and functional gene, RAPD, SSCP, TLC thin layer chromatography, whole cell fatty acid analysis and identification, (G+C) mol% determination, DNA/DNA homology determination, etc.
E. coli Gene Expression
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Creative Biogene is a leading biotech company engaged in E.coli gene expression service for clients around the world across both academic institutions and biotech/pharmaceutical industries. Creative Biogene’s aim is to provide our clients the highest quality services yet with the precision, speed, value, and build strong partnerships. Creative Biogene specializes in the development of cutting-edge technologies in expression, production, and manufacturing of microbial enzymes.
Gute psychopädiatrische Pflege zu Hause: was ist das?
Creators: name: Lanz, Brigitte Wenger
name: Elmer, Franz
name: Hahn, Sabine
Publisher: name: Thieme
Year: 2022

description: Die Nachfrage nach professioneller psychopädiatrischer Pflege von Kindern und Jugendlichen im häuslichen Setting hat in den vergangenen Jahren stark zugenommen. Doch wie steht es um die Qualität der geleisteten Pflege? Der vorliegende Beitrag geht der Frage nach, was unter guter psychopädiatrischer Pflege zu Hause verstanden wird. Es werden die Perspektiven betroffener Jugendlicher, Eltern und Fachpersonen beleuchtet.
MOESM2 of Comparison of aldehyde-producing activities of cyanobacterial acyl-(acyl carrier protein) reductases
Creators: name: Kudo, Hisashi
name: Nawa, Ryota
name: Hayashi, Yuuki
name: Arai, Munehito
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Developmental Biology
subject: Inorganic Chemistry

description: Additional file 2: Table S2. Amino acid sequence identity (%) among the AAR sequences used in the present study.
Bacillus Expression System
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2023

description: Creative Biogene is a microbiotech company offering high-quality gene expression services in Bacillus for our esteemed clients around the world across both academic institutions and biotech/pharmaceutical industries. With our strong technical force, we specialize in providing more cost-effective gene expression services to accelerate the global research in microbial enzymes and recombinant proteins.
ABC Transporter Stable Cell Lines
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: ATP-binding cassette (ABC) transporters are transmembrane proteins that act as drug efflux pumps and are associated with multi-drug resistance (MDR) in cancer. Two specific proteins that belong to this protein superfamily are P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP). ABC transporters have a wide range of functions, including transporting a variety of biological molecules and protecting cells from endogenous and exogenous toxins. Efflux pumps from the ABC transporter family can also be expressed by the tumor cells themselves, leading to the development of intrinsic chemoresistance. Therefore, the study of ABC transporters is expected to be helpful in the drug development process.
[Écoles d’été Cuba 1971 – Cher collègue, Vous avez dû recevoir]
Creators: name: Yves, Lacoste
name: Lacoste, Yves
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: Comité de Liaison Scientifique et Universitaire Franco-cubain
Écoles d’été
Section Géographie

description: Destinataire : Inconnu
description: L’auteur de la lettre réagit suite à une circulaire de Dacunha-Castelle dans laquelle il serait fait mention d’une impréparation de la Section Géographie pour les Écoles d’été 1971. Il développe une argumentation à ce sujet.
description: El autor de la carta reacciona a una circular de Dacunha-Castelle en la que se menciona una falta de preparación de la Sección de Geografía para las Escuelas de Verano de 1971. Desarrolla una argumentación al respecto.
description: Notes : Papier à en-tête : Université de Paris VIII. La lettre est accompagnée d’une liste avec les noms et adresses du Président du Comité, du coordinateur du Groupe Géographie à l’École d’été 1970, et des géographes qui doivent participer aux Écoles d’été 1971.
description: Source: DDC-C-1971-05-25
description: Source: Localisation de la ressource : Centre de Recherches Latino-Américaines (CRLA–Archivos, ITEM UMR8132). MSHS - Bât. A5, 1er étage 5 rue Théodore Lefebvre - TSA21103. 86073 Poitiers cedex 9.
Zulässige Unehrlichkeit aus der Perspektive von Jugendlichen : sozialwissenschaftliche Reflexionen zur Tugend Ehrlichkeit im Schulkontext
Dishonesty from the View of Youths. Some Social ScientificReflections on the Virtue of Honesty in a School Context
Creators: name: Chiapparini, Emanuela
Publisher: name: Beltz Juventa
Year: 2014
Subjects: 302: Soziale Interaktion
370: Bildung und Erziehung; Normen
Regeln
Jugend
Schule
Ehrlichkeit
moralisches Wissen
Agency

description: In der gegenwärtigen Schulforschung werden Tugenden – obwohl in der öffentlichen Debatte oft kontrovers diskutiert – nur marginal und aus der Perspektive der Erziehungsbeauftragten beforscht. Im Gegensatz dazu thematisiert der Artikel die schulrelevante Tugend Ehrlichkeit aus der Perspektive der Jugendlichen. Auf der Grundlage einer umfangreichen Studie zu Deutungen von Ehrlichkeitspraxen wird im vorliegenden Beitrag exemplarisch der Blick auf zwei reale Dilemmasituationen gerichtet, in denen die Aushandlung von konventionellen und unkonventionellen Ehrlichkeitsregeln besonders klar ersichtlich ist und damit eine Situierung zwischen Selbst- und Fremdbestimmung detailliert vollzogen wird. Die aus der rekonstruktiven Textanalyse gewonnenen Befunde verweisen auf eine vielschichtige Verwendung der Tugend Ehrlichkeit in der Schulpraxis, die sich nicht nur auf rhetorische oder moralische Aspekte limitiert, sondern von institutionellen, sozialen und individuellen Normen abhängig ist. Die Ergebnisse verweisen auf bestimmte Schulsituationen, in denen aus der Sicht der Jugendlichen unehrliche Regeln legitim und gerechtfertigt sind und auf Zusammenhänge mit gewissen Lehrpersonen. Zudem lassen sich implizit Gerechtigkeitsvorstellungen der Schülerinnen und Schüler ablesen, die sie an die Schule stellen. Der Artikel soll mittels der praxisorientierten Thematisierung der Tugend Ehrlichkeit einen wichtigen Beitrag zum Thema empirische Tugendforschung im Schulkontext leisten.
description: Virtues are only occasionally investigated in current education research in secondaryschools, and public discussions exist only from the adult point of view. By contrast,this article addresses the practical interpretations of the concept of “honesty” amongyouths in a school context and presents two dilemmas highlighting conventionaland unconventional rules of honesty at school, based on research carried out usingqualitative methods, investigating how youngsters deal with “honesty” in their dai-ly school lives. Youths must decide upon their position with respect to honesty,taking into account both intrinsic and external factors. I will show by example thatthe virtue honesty in the school context has not only a rhetorical or moral basis,but depends also on institutional, social and individual norms. Furthermore, theresults presented emphasize the pupils’ own concept of justice within the school.From this it follows that in certain situations and in classes taught by certain teach-ers, dishonest rules are legitimate and justified from the youths’ point of view. Withthis practice-orientated research, virtues can be explained in terms of social andinstitutional norms in the school context
Digitale Hilfe für betreuende Angehörige: Neuenburg setzt neue Massstäbe
Creators: name: Michel, Claudia
name: Soom Ammann, Eva
name: Descloux, Olivier
name: Bignens, Serge
Publisher: name: Berner Fachhochschule BFH, Soziale Arbeit
Year: 2023

description: Betreuende Angehörige riskieren müde, erschöpft oder krank zu werden, sich zu isolieren und finanzielle Einbussen zu erleiden. Damit sie gesund bleiben und ihre Tätigkeit als sinnstiftend erleben können, sind sie auf Hilfe angewiesen. Der Kanton Neuenburg hat es sich zusammen mit der BFH zur Aufgabe gemacht, Angehörige passgenau zu unterstützen: Entstanden ist die App «approches».
Application of Flow Cytometry in Oncology
Creators: name: Cole, Hannah
Publisher: name: Zenodo
Year: 2023

description: Flow cytometry has been widely used in clinical and basic laboratory for diagnostic and research purposes, since Mack Fulwyler first developed the flow cytometers in 1965. Flow cytometry is capable of measuring the optical and fluorescent characteristics of a single cell or any other particle such as microorganisms, nuclei, and chromosome prepared in a fluid stream when they pass through the light source. Subsequent advancements in the fields of computer science, laser technology, monoclonal antibody production, cytochemistry and fluorochrome chemistry enable simultaneous analysis of 20 features within an individual cell in a quantitative and qualitative manner. The parameters measured by flow cytometry include cell size, cytoplasmic complexity/granularity, nucleic acid content and various intracellular/membrane proteins.
Giant Slalom: Analysis of Course Setting, Steepness and Performance of Different Age Groups - A Pilot Study
Creators: name: Brühin, Björn
name: Janssen, Rowie JF
name: Guillaume, Sebastien
name: Gander, Mara
name: Oberle, Felix
name: Lorenzetti, Silvio
name: Romann, Michael
Publisher: name: Frontiers Research Foundation
Year: 2020
Subjects: Course setting Elite sports Giant slalom Performance Youth sports

description: Introduction: Giant slalom is the core discipline of alpine skiing, and each race has its own specific course and terrain characteristics. These variations may explain differences in the speed and time per turn profiles, which are essential for performance development and injury prevention. This study aims to address the differences in course setting and steepness of the different course sections (flat-medium-steep) and compare them to the performance parameters among young (U12, U14, U16) and older (U18, U21, elite) male athletes. Methods: The study examined a total sample size of 57 male athletes; 7 from elite level, 11 from U21, 13 from U18, 6 from U16, 13 from U14, and 7 from U12. The athletes wore a portable global navigation satellite system (GNSS) sensor to extract performance parameters. The course profiles and gate positions of nine runs were measured with differential GNSS. The runs were divided into flat, medium and steep sections. From the performance parameters (speed, time per turn, etc.) and the course setting variables, the mean value per section was calculated and used for the further analysis. Results: In total, 192 run sections from 88 runs were recorded and analyzed. Comparisons between course settings in young and older classes showed no significant differences. However, the turning angles and horizontal gate distances were smaller in flat sections. Average speed (49.77 vs. 65.33 km/h) and time per turn (1.74 vs. 1.41 s) differed significantly between young and U21/elite categories. In medium terrain sections U21 and elite athletes spent more time in the gliding phase compared to all other athletes. Discussion: It seems to be a reasonable that, given similar course setting and steepness, speed increases concurrently with the technical and tactical skills of the athlete. Moreover, the finding that the elite athletes spent more time in the gliding phase could be crucial for understanding technique and performance development in young athletes.
Effectiveness and tolerability of eptinezumab in treating patients with migraine resistant to conventional preventive medications and CGRP (receptor) antibodies : a multicentre retrospective real-world analysis from Germany
Creators: name: Scheffler, Armin
name: Wenzel, Pauline
name: Bendig, Merle
name: Eikermann, Astrid
name: Basten, Jale
name: Kleinschnitz, Christoph
name: Nsaka, Michael
name: Lindner, Diana
name: Naegel, Steffen
name: Burow, Philipp
name: Fleischmann, Robert
name: Holle-Lee, Dagny
Publisher: name: Universitäts- und Landesbibliothek Sachsen-Anhalt
Year: 2024
Subjects: subject: 610

description: Background: Eptinezumab is a monoclonal antibody that targets calcitonin gene-related peptide (CGRP mAb) and is used for migraine prophylaxis. Efficacy data are mainly from clinical trials, real-world data are hardly available yet. Reimbursement policy in Germany leads to eptinezumab mainly being used in patients having failed pre-treatment with other CGRP mAb. To date, it is unclear whether eptinezumab is efficacious and well tolerated in this population and how the treatment response differs from patients who are naive to CGRP mAbs. Methods: We analysed clinical routine data of 79 patients (episodic migraine (EM): n = 19; chronic migraine (CM): n = 60) from four different centres in Germany. All patients were treated with eptinezumab (100mg). Differences in monthly headache (MHD), migraine (MMD) and acute medication days (AMD) after three months were analysed. The correlation of response with the number of CGRP mAb failures was evaluated. Significance level has been corrected (alpha = 0.017). Results: After three months MHD, MMD and AMD were significantly reduced. In EM, the median reduction for MHD was 4.0 days (IQR: -6.5 to -1.0; p = 0.001), for MMD 3.0 days (IQR: -5.5 to -1.5; p < 0.001) and for AMD 2.0 days (IQR: -5.0 to -0.5; p = 0.006). In CM, median reduction of MHD was 4 days (IQR: -8.0 to 0.0; p < 0.001), 3.0 days (IQR: -6.0 to-1.0; p < 0.001) for MMD and 1.0 day (IQR: -5.0 to 0.0; p < 0.001) for AMD. All patients were resistant to conventional preventive therapies and most to CGRP mAbs. Fourteen patients had never received a CGRP mAb and 65 patients had received at least one mAb without sufficient effectiveness and/or intolerability (one: n = 20, two: n = 28, three: n = 17). There was a significant association between the number of prior therapies and the 30% MHD responder rate (none: 78.6%, one: 45.0%, two: 32.1%, three: 23.5%, p = 0.010). Regarding tolerability, 10.4% (8/77) reported mild side effects. Conclusions: The effectiveness of eptinezumab is significantly reduced in patients who have not previously responded to other CGRP mAbs. However, limitations such as the retrospective nature of the analysis, the small sample size and the short treatment period with only the lower dose of eptinezumab must be considered when interpreting the results.
Escherichia coli Genome Editing
Creators: name: Brady, Marcia
Publisher: name: Zenodo
Year: 2024

description: Escherichia coli is one of the most extensively studied bacteria that becomes an instrumental model system for the understanding of a plethora of gene functions and regulations in both prokaryotes and eukaryotes. In addition, it's a very versatile host for the production of heterologous proteins and their mass-production in industrial fermentation systems. E.coli also plays an invaluable role in modern biological engineering and industrial microbiology. More applications are expected to be developed due to the modern molecular technique of the genome editing.
J. Ma, POLIS: A New History of the Ancient Greek City-State from the Early Iron Age to the End of Antiquity, Princeton & Oxford 2024. Princeton University Press, xv+713 Sayfa. ISBN: 9780691155388 (hardback) | ISBN 9780691255484 (ebook)
Creators: name: Dilek, Emre
Publisher: name: Zenodo
Year: 2024

description: Book notice
Validation of an In Vitro Digestive System for Studying Macronutrient Decomposition in Humans
Creators: name: Kopf, Katrin Annika
name: Schwander, Flurina
name: Gijs, Martin
name: Vergères, Guy
name: Portmann, Reto
name: Egger, Lotti
Publisher: name: Oxford University Press
Year: 2012
Subjects: high pressure liquid chromatography procedure
digestion
gastrointestinal system
enterocytes
food
intestines
milk
peptides
nutrients
macronutrient

description: The digestive process transforms nutrients and bioactive compounds contained in food to physiologically active compounds. In vitro digestion systems have proven to be powerful tools for understanding and monitoring the complex transformation processes that take place during digestion. Moreover, the investigation of the physiological effects of certain nutrients demands an in vitro digestive process that is close to human physiology. In this study, human digestion was simulated with a 3-step in vitro process that was validated in depth by choosing pasteurized milk as an example of a complex food matrix. The evolution and decomposition of the macronutrients was followed over the entire digestive process to the level of intestinal enterocyte action, using protein and peptide analysis by SDS-PAGE, reversed-phase HPLC, size exclusion HPLC, and liquid chromatography-MS. The mean peptide size after in vitro digestion of pasteurized milk was 5–6 amino acids (AA). Interestingly, mostly essential AA (93.6%) were released during in vitro milk digestion, a significantly different relative distribution compared to the total essential AA concentration of bovine milk (44.5%). All TG were degraded to FFA and monoacylglycerols. Herein, we present a human in vitro digestion model validated for its ability to degrade the macronutrients of dairy products comparable to physiological ranges. It is suited to be used in combination with a human intestinal cell culture system, allowing ex vivo bioavailability measurements and assessment of the bioactive properties of food components.