cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability
Creators: name: Wozniak, J.R.
name: Miller, N.C.
name: Brearley, A.M.
name: Kroupina, M.G.
name: Hoecker, H.L.
name: Fink, B.A.
name: Boys, C.J.
name: Zeisel, S.H.
name: Fuglestad, A.J.
name: Georgieff, M.K.
name: Eckerle, J.K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: There are no biological treatments for fetal alcohol spectrum disorders (FASDs), lifelong conditions associated with physical anomalies, brain damage, and neurocognitive abnormalities. In preclinical studies, choline partially ameliorates memory and learning deficits from prenatal alcohol exposure. This phase I pilot study evaluated the feasibility, tolerability, and potential adverse effects of choline supplementation in children with FASD. We hypothesized that choline would be well tolerated with minimal adverse events. The study design was a double-blind, randomized, placebo-controlled trial. Participants included 20 children aged 2.5 to 4.9 years with prenatal alcohol exposure and FASD diagnoses. Participants were randomly assigned to 500 mg choline or placebo daily for 9 months (10 active, 10 placebo). Primary outcome measures included feasibility, tolerability, adverse effects, and serum choline levels. Seventeen participants completed the study. Compliance was 82% to 87%, as evidenced by parent-completed log sheets and dose counts. Periodic 24-hour dietary recalls showed no evidence of dietary confounding. Adverse events were minimal and were equivalent in the active and placebo arms with the exception of fishy body odor, which occurred only in the active group. There were no serious adverse events to research participants. This phase I pilot study demonstrates that choline supplementation at 500 mg/d for 9 months in children aged 2 to 5 years is feasible and has high tolerability. Further examination of the efficacy of choline supplementation in FASD is currently underway.
Sonnenfleckenzeichnung Nr. 133.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 18.06.2010, 07:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Censorship is Futile
Creators: name: Nabi, Zubair
Publisher: name: arXiv
Year: 2014
Subjects: subject: Computers and Society (cs.CY)
subject: FOS: Computer and information sciences

description: The Internet has become the new battle ground between authoritarian regimes and ordinary individuals who want unimpeded access to information. The immense popularity of online activism and citizen journalism enabled by social media has instigated state level players to partially or completely block access to the Internet. In return, individuals and organizations have been employing various anti-censorship tools to circumvent these restrictions. In this paper, we claim that censorship is futile as not only has it been ineffective in restricting access, it has also had the side-effect of popularising blocked content. Using data from Alexa Web Rankings, Google Trends, and YouTube Statistics, we quantify the ineffectiveness of state level censorship in Pakistan and Turkey and highlight the emergence of the Streisand Effect. We hope that our findings will, a) prove to governments and other players the futility of their actions, and b) aid citizens around the world in using legal measures to counteract censorship by showing its ineffectiveness.
description: First Monday, Volume 19, Number 11 - 3 November 2014
(502226) Katherine Leitch Younger
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(502228) Arthur Francis Cuff
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 168.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.07.2010, 08:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Stokesian swimmers and active particles
Creators: name: Felderhof, B. U.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: The net steady state flow pattern of a distorting sphere is studied in the framework of the bilinear theory of swimming at low Reynolds number. It is argued that the starting point of a theory of interacting active particles should be based on such a calculation, since any arbitrarily chosen steady state flow pattern is not necessarily the result of a swimming motion. Furthermore, it is stressed that as a rule the phase of stroke is relevant in hydrodynamic interactions, so that the net flow pattern must be used with caution.
description: 11 pages, 6 figures
Diet-gene interactions underlie metabolic individuality and influence brain development: Implications for clinical practice derived from studies on choline metabolism
Creators: name: Zeisel, S.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: One of the underlying mechanisms for metabolic individuality is genetic variation. Single nucleotide polymorphisms (SNPs) in genes of metabolic pathways can create metabolic inefficiencies that alter the dietary requirement for, and responses to, nutrients. These SNPs can be detected using genetic profiling and the metabolic inefficiencies they cause can be detected using metabolomic profiling. Studies on the human dietary requirement for choline illustrate how useful these new approaches can be, as this requirement is influenced by SNPs in genes of choline and folate metabolism. In adults, these SNPs determine whether people develop fatty liver, liver damage and muscle damage when eating diets low in choline. Because choline is very important for fetal development, these SNPs may identify women who need to eat more choline during pregnancy. Some of the actions of choline are mediated by epigenetic mechanisms that permit 'retuning' of metabolic pathways during early life.
Sonnenfleckenzeichnung Nr. 20.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 24.01.2010, 10:30, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency
Creators: name: Spencer, M.D.
name: Fodor, A.A.
name: Reid, R.W.
name: Hamp, T.J.
name: Fischer, L.M.
name: Zeisel, S.H.
Publisher: name: W.B. Saunders
Year: 2011

description: Background & Aims: Nonalcoholic fatty liver disease affects up to 30% of the US population, but the mechanisms underlying this condition are incompletely understood. We investigated how diet standardization and choline deficiency influence the composition of the microbial community in the human gastrointestinal tract and the development of fatty liver under conditions of choline deficiency. Methods: We performed a 2-month inpatient study of 15 female subjects who were placed on well-controlled diets in which choline levels were manipulated. We used 454-FLX pyrosequencing of 16S ribosomal RNA bacterial genes to characterize microbiota in stool samples collected over the course of the study. Results: The compositions of the gastrointestinal microbial communities changed with choline levels of diets; each individual's microbiome remained distinct for the duration of the experiment, even though all subjects were fed identical diets. Variations between subjects in levels of Gammaproteobacteria and Erysipelotrichi were directly associated with changes in liver fat in each subject during choline depletion. Levels of these bacteria, change in amount of liver fat, and a single nucleotide polymorphism that affects choline were combined into a model that accurately predicted the degree to which subjects developed fatty liver on a choline-deficient diet. Conclusions: Host factors and gastrointestinal bacteria each respond to dietary choline deficiency, although the gut microbiota remains distinct in each individual. We identified bacterial biomarkers of fatty liver that result from choline deficiency, adding to the accumulating evidence that gastrointestinal microbes have a role in metabolic disorders.
Sonnenfleckenzeichnung Nr. 92.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.04.2010, 07:15, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 22.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.01.2010, 09:30, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 260.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 17.11.2010, 08:30, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline
Creators: name: Zeisel, S.H.
name: Lawton, K.A.
name: Berger, A.
name: Milburn, M.V.
name: Jia, W.
name: Da Costa, K.-A.
name: Fischer, L.M.
name: Sha, W.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Choline is an essential nutrient, and deficiency causes liver and muscle dysfunction. Common genetic variations alter the risk of developing organ dysfunction when choline deficient, probably by causing metabolic inefficiencies that should be detectable even while ingesting a normal choline-adequate diet. We determined whether metabolomic profiling of plasma at baseline could predict whether humans will develop liver dysfunction when deprived of dietary choline. Fifty-three participants were fed a diet containing 550 mg choline/70 kg/d for 10 d and then fed <50 mg choline/70 kg/d for up to 42 d. Participants who developed organ dysfunction on this diet were repleted with a choline-adequate diet for ≥3 d. Plasma samples, obtained at baseline, end of depletion, and end of repletion, were used for targeted and nontargeted metabolomic profiling. Liver fat was assessed using magnetic resonance spectroscopy. Metabolomic profiling and targeted biochemical analyses were highly correlated for the analytes assessed by both procedures. In addition, we report relative concentration changes of other small molecules detected by the nontargeted metabolomic analysis after choline depletion. Finally, we show that metabolomic profiles of participants when they were consuming a control baseline diet could predict whether they would develop liver dysfunction when deprived of dietary choline.
Discussion on the spectral coherence between planetary, solar and climate oscillations: a reply to some critiques
Creators: name: Scafetta, Nicola
Publisher: name: arXiv
Year: 2014
Subjects: subject: Geophysics (physics.geo-ph)
subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Atmospheric and Oceanic Physics (physics.ao-ph)
subject: FOS: Physical sciences

description: During the last few years a number of works have proposed that planetary harmonics regulate solar oscillations and the Earth climate. Herein I address some critiques. Detailed analysis of the data do support the planetary theory of solar and climate variation. In particular, I show that: (1) high-resolution cosmogenic 10Be and 14C solar activity proxy records both during the Holocene and during the Marine Interglacial Stage 9.3 (MIS 9.3), 325-336 kyr ago, present four common spectral peaks at about 103, 115, 130 and 150 yrs (this is the frequency band that generates Maunder and Dalton like grand solar minima) that can be deduced from a simple solar model based on a generic non-linear coupling between planetary and solar harmonics; (2) time-frequency analysis and advanced minimum variance distortion-less response (MVDR) magnitude squared coherence analysis confirm the existence of persistent astronomical harmonics in the climate records at the decadal and multidecadal scales when used with an appropriate window length (110 years) to guarantee a sufficient spectral resolution. However, the best coherence test can be currently made only by comparing directly the temperature and astronomical spectra as done in Scafetta (J. Atmos. Sol. Terr. Phys. 72(13), 951-970, 2010). The spectral coherence between planetary, solar and climatic oscillations is confirmed at the following periods: 5.2 yr, 5.93 yr, 6.62 yr, 7.42 yr, 9.1 yr (main lunar tidal cycle), 10.4 yr (related to the 9.93-10.87-11.86 yr solar cycle harmonics), 13.8-15.0 yr, 20 yr, 30 yr and 61 yr, 103 yr, 115 yr, 130 yr, 150 yr and about 1000 year. This work responds to the critiques of Cauquoin et al. (Astron. Astrophys. 561, A132, 2014) who ignored alternative planetary theories of solar variations, and of Holm (J. Atmos. Sol. Terr. Phys. 110-111, 23-27, 2014) who used inadequate physical and time frequency analysis of the data.
description: 35 pages, 13 figures
Sonnenfleckenzeichnung Nr. 184.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 10.08.2010, 08:00, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 167.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.07.2010, 14:15, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Deletion of murine choline dehydrogenase results in diminished sperm motility
Creators: name: Blusztajn, J.K.
name: Johnson, A.R.
name: Guo, Z.
name: Teng, Y.-W.
name: Thresher, R.J.
name: Craciunescu, C.N.
name: Zeisel, S.H.
Publisher: name: FASEB
Year: 2010

description: Choline dehydrogenase (CHDH) catalyzes the conversion of choline to betaine, an important methyl donor and organic osmolyte. We have previously identified single nucleotide polymorphisms (SNPs) in the human CHDH gene that, when present, seem to alter the activity of the CHDH enzyme. These SNPs occur frequently in humans. We created a Chdh-/- mouse to determine the functional effects of mutations that result in decreased CHDH activity. Chdh deletion did not affect fetal viability or alter growth or survival of these mice. Only one of eleven Chdh-/- males was able to reproduce. Loss of CHDH activity resulted in decreased testicular betaine and increased choline and PCho concentrations. Chdh+/+ and Chdh-/- mice produced comparable amounts of sperm; the impaired fertility was due to diminished sperm motility in the Chdh-/- males. Transmission electron microscopy revealed abnormal mitochondrial morphology in Chdh-/- sperm. ATP content, total mitochondrial dehydrogenase activity and inner mitochondrial membrane polarization were all significantly reduced in sperm from Chdh -/- animals. Mitochondrial changes were also detected in liver, kidney, heart, and testis tissues. We suggest that men who have SNPs in CHDH that decrease the activity of the CHDH enzyme could have decreased sperm motility and fertility.
title: ‘The memory that is inherited from all […] in geometric progression.’ The shared geometric visions of Jorge Luis Borges and William Butler Yeats.
Creators: name: Gaynor, Grace
Publisher: name: University of Liverpool Repository
Year: 2026

description: The twentieth-century Argentinean writer Jorge Luis Borges played a leading and early formative role in the reception of Irish modernist literature in Latin America. However, his interest in the Irish writer William Butler Yeats has received little critical attention to date, and this thesis endeavours to redress this imbalance. Specifically, this thesis considers Yeats’s use of geometric imagery in his writing, and how Borges appropriated this imagery to suggest an affinity between the temporalities of modernity and changing cartographies of Ireland and Argentina in the early twentieth century. Underpinning this thesis, and included as an ‘Appendix’, is my Borges/Yeats Index of References, which outlines the references that Borges made to Yeats, and the thematic contexts in which these references arise. This Borges/Yeats Index facilitates an analysis of both the quantitative and qualitative significance of these references, which are examined in greater detail in each chapter. Specifically, this thesis situates my Borges/Yeats Index in other scholarly attempts to organise Borges’s work, and it offers significant attention to two of the most important references that Borges makes to Yeats, which are the lines of Yeats’s poetry he chooses as epigraphs to two of his short stories. This thesis also contextualises these references in Borges’s broader interest in other Irish writers and Ireland, and considers the specific affinity that Borges proposes between the literature of Argentina and Ireland, and the crucial role that Yeats played in the formulation of these ideas. Following on from these discussions is a consideration of the specific Yeatsian symbols which occur frequently in Borges’s references to Yeats, and Borges’s assimilation of these symbols into his own work. Another theme which occurs frequently in these references is memory, and this thesis considers Borges’s association of Yeats with the notion of ‘great memory’, and ideas regarding literary precursors and intertextuality that are associated with this term. The final consideration of this thesis is Yeats’s geometric systemisations, and the ways in which Borges utilises the totalising aspects of these systems to explore and subvert systemisations of time and history in his own work.
Sonnenfleckenzeichnung Nr. 270.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 04.12.2010, 08:45, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Fast Generation of Random Spanning Trees and the Effective Resistance Metric
Creators: name: Madry, Aleksander
name: Straszak, Damian
name: Tarnawski, Jakub
Publisher: name: arXiv
Year: 2015
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: Discrete Mathematics (cs.DM)
subject: FOS: Computer and information sciences

description: We present a new algorithm for generating a uniformly random spanning tree in an undirected graph. Our algorithm samples such a tree in expected $\tilde{O}(m^{4/3})$ time. This improves over the best previously known bound of $\min(\tilde{O}(m\sqrt{n}),O(n^ω))$ -- that follows from the work of Kelner and Mądry [FOCS'09] and of Colbourn et al. [J. Algorithms'96] -- whenever the input graph is sufficiently sparse. At a high level, our result stems from carefully exploiting the interplay of random spanning trees, random walks, and the notion of effective resistance, as well as from devising a way to algorithmically relate these concepts to the combinatorial structure of the graph. This involves, in particular, establishing a new connection between the effective resistance metric and the cut structure of the underlying graph.
(502225) Charles Younger
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 262.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.11.2010, 09:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene
Creators: name: Craciunescu, C.N.
name: Mehedint, M.G.
name: Niculescu, M.D.
name: Zeisel, S.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: Maternal choline availability is essential for fetal neurogenesis. Choline deprivation (CD) causes hypomethylation of specific CpG islands in genes controlling cell cycling in fetal hippocampus. We now report that, in C57BL/6 mice, CD during gestational days 12-17 also altered methylation of the histone H3 in E17 fetal hippocampi. In the ventricular and subventricular zones, monomethyl-lysine 9 of H3 (H3K9me1) was decreased by 25% (P<0.01), and in the pyramidal layer, dimethyl-lysine 9 of H3 (H3K9me2) was decreased by 37% (P<0.05). These changes were region specific and were not observed in whole-brain preparations. Also, the same effects of CD on H3 methylation were observed in E14 neural progenitor cells (NPCs) in culture. Changes in G9a histone methyltransferase might mediate altered H3K9me2,1. Gene expression of G9a was decreased by 80% in CD NPCs (P<0.001). In CD, H3 was hypomethylated upstream of the RE1 binding site in the calbindin 1 promoter, and 1 CpG site within the calbindin1 promoter was hypermethylated. REST binding to RE1 (recruits G9a) was decreased by 45% (P<0.01) in CD. These changes resulted in increased expression of calbindin 1 in CD (260%; P<0.05). Thus, CD modulates histone methylation in NPCs, and this could underlie the observed changes in neurogenesis.
Gauss-Bonnet Inflation
Creators: name: Kanti, Panagiota
name: Gannouji, Radouane
name: Dadhich, Naresh
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We consider an Einstein-Scalar-Gauss-Bonnet gravitational theory, and argue that at early times the Ricci scalar can be safely ignored. We then demonstrate that the pure scalar-Gauss-Bonnet theory, with a quadratic coupling function, naturally supports inflationary -- de Sitter -- solutions. During inflation, the scalar field decays exponentially and its effective potential remains always bounded. The theory contains also solutions where these de Sitter phases possess a natural exit mechanism and are replaced by linearly expanding -- Milne -- phases.
description: 6 pages, Revtex, 3 figures, introduction updated, a section added, typos corrected, accepted as a Rapid Communications article in Physical Review D
Sonnenfleckenzeichnung Nr. 172.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.07.2010, 08:30, erstellt von Marco Cagnotti
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Energy dependence of space-time extent of pion source in nuclear collisions
Creators: name: Okorokov, V. A.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Nuclear Experiment (nucl-ex)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Energy dependence of space-time parameters of pion emission region at freeze-out is studied for collisions of various ions and for all experimentally available energies. The using of femtoscopic radii scaled on the averaged radius of colliding ions is suggested. This approach allows the expansion of the set of interaction types, in particular, on collisions of non-symmetrical ion beams which can be studied within the framework of common treatment. There is no sharp changing of femtoscopic parameter values with increasing of initial energy. Analytic functions suggested for smooth approximations of energy dependence of femtoscopic parameters demonstrate reasonable agreement with most of experimental data at $\sqrt{s_{NN}} \geq 5$ GeV. Estimations of some observables are obtained for energies of the LHC and FCC project.
description: 8 pages, 3 figures, 2 tables. X-th Workshop on particle correlations and femtoscopy (WPCF2014). Gyongyos, Hungary. August 25-29, 2014
Sonnenfleckenzeichnung Nr. 67.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 28.03.2010, 09:45, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Sonnenfleckenzeichnung Nr. 194.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 20.08.2010, 07:30, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 4.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
A grand challenge for nutrigenomics
Creators: name: Zeisel, S.H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The low hanging fruit in genetics research has mostly been harvested, and now the work of studying genes as part of systems biology is well underway. Metabolism and nutrition seem to be an ideal complex system in which to apply the knowledge and methods of genetics and genomics. Diet is perhaps the most important environmental factor we are exposed to. Nutritional factors are thought to be the cause of 30–60% of cancers (similar in magnitude to smoking; Doll, 1992), diabetes is a nutritional/metabolic disorder, we are all familiar with the cholesterol–cardiovascular disease relationship, and obesity is a pressing nutritional problem, with a majority of Americans overweight and expanding rapidly (Ogden et al., 2007). If genetic scientists are looking for a complex system to step up to and address, what better choice? Hence, the developing discipline of nutrigenomics.
title: J.M. Synge, Modernism, and Political Protest
Creators: name: Hewitt, SE
Publisher: name: University of Liverpool Repository
Year: 2018

description: This thesis explores the works of the Irish writer J.M. Synge (1871-1909). By first seeking to define and examine the tenets of Synge’s artistic, spiritual and political value system, and by considering his works in a broadly chronological order, this research shows that Synge’s writings (and his trajectory into modernism) were a reaction to both literary and social modernity. Over the course of his career, Synge’s foundational value system, or ‘creed’, was subjected to a number of shocks by his encounters with the modernisation of rural Ireland and the political climate of the cultural Revival, which led him to a continuous literary experimentation. Ultimately, this thesis argues that Synge’s work, as it moves towards an increasingly modernist aesthetic, can be understood as an act of both literary and political protest. One of the main innovations of this thesis is its methodology. Throughout, archival materials are used in order to uncover the processes of authorial revision undertaken prior to the publication of Synge’s texts, showing how he edited, glossed, and subverted his previous work in line with his changing views on modernisation and on his earlier, more overt Romanticism. In addition to this, each chapter of this thesis explores Synge’s composition alongside his contemporary reading materials, showing the influence of various writers and broader discourses on the works discussed. In doing so, the thesis uncovers Synge’s interest in occultism, his engagement with various socialist works, his reading in evolutionary theory, and his later reaction against early eugenic nationalisms, and demonstrates the close relationship between his published and performed works and these discourses. Furthermore, in showing the importance of socialist politics to Synge’s literary development, this thesis demonstrates how several concerns typical of modernism (such as occult spirituality, degeneration, and eugenics) are approached by a leftist writer, and how left-wing politics manifest in early modernist literature. By tracing Synge’s ongoing reaction to modernisation, and his trajectory into literary modernism, this thesis explores in detail the contested relationship between Revivalism and modernism in the Irish context, and thus, through a study of one of Ireland’s major dramatists, lays the groundwork for further scholarly exploration of the interplay between these two movements. Finally, by exploring Synge’s afterlife in modernist writings, both as a modernising impulse and as a figure of modernist protest, this thesis suggests ways in which the work of later modernists might be reassessed in light of Synge’s work.
Artifact for "AalWiNes: A Fast and Quantitative What-If Analysis Tool for MPLS Networks"
Creators: name: Jensen, Peter Gjøl
name: Kristiansen, Dan
name: Schmid, Stefan
name: Schou, Morten Konggaard
name: Schrenk, Bernhard Clemens
name: Srba, Jiri
Publisher: name: Zenodo
Year: 2020

description: Artifact for the paper "AalWiNes: A Fast and Quantitative What-If Analysis Tool for MPLS Networks", accepted at CoNEXT 2020. This artifact contains a reproducibility-package with experiments and scripts to reproduce the results reported in the paper. The source code is available on GitHub:
 - Source code for AalWiNes: https://github.com/DEIS-Tools/AalWiNes
 - Source code for the PDA engine: https://github.com/DEIS-Tools/PDAAAL
 - Source code for the GUI: https://github.com/DEIS-Tools/VisuAalWiNes A demo of the GUI is available at: https://demo.aalwines.cs.aau.dk Reproducibility The reproducibility-package is only available for Linux. The package contains:
 - bin (programs binaries)
 - operator-network (for the table in the paper)
 - synthetic-networks (for the plot in the paper)
 - results (pre-populated)
 - Scripts to run tests and create plot and table. Please see the README.txt file for further information.
Sonnenfleckenzeichnung Nr. 77.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 11.04.2010, 09:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Plan S - Feedback
Creators: name: Köhler, Martin
Publisher: name: Deutsches Elektronen-Synchrotron, DESY, Hamburg
Year: 2017

description: HGF AK Library and Information Management, Berlin, DESY, Germany, 2 Apr 2019 - 3 Apr 2019
description: Status of the HGF library feedback to cOAlition S and questions/thoughts on the relation of the Wiley DEAL and Plan S
(502227) Henry Robert Younger
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Sonnenfleckenzeichnung Nr. 25.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.01.2010, 11:15, erstellt von Andrea Manna
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 2.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
Dietary docosahexaenoic acid supplementation modulates hippocampal development in the pemt-/- mouse
Creators: name: Mehedint, M.G.
name: da Costa, K.-A.
name: Rai, K.S.
name: Craciunescu, C.N.
name: Zeisel, S.H.
name: Parikh, K.
name: Sanders, L.M.
name: McLean-Pottinger, A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: The development of fetal brain is influenced by nutrients such as docosahexaenoic acid (DHA, 22:6) and choline. Phosphatidylethanolamine-N-methyltransferase (PEMT) catalyzes the biosynthesis of phosphatidylcholine from phosphatidylethanolamine enriched in DHA and many humans have functional genetic polymorphisms in the PEMT gene. Previously, it was reported that Pemt-/- mice have altered hippocampal development. The present study explores whether abnormal phosphatidylcholine biosynthesis causes altered incorporation of DHA into membranes, thereby influencing brain development, and determines whether supplemental dietary DHA can reverse some of these changes. Pregnant C57BL/6 wild type (WT) and Pemt-/- mice were fed a control diet, or a diet supplemented with 3 g/kg of DHA, from gestational day 11 to 17. Brains from embryonic day 17 fetuses derived from Pemt-/- dams fed the control diet had 25-50% less phospholipid-DHA as compared with WT (p < 0.05). Also, they had 60% more neural progenitor cell proliferation (p < 0.05), 60% more neuronal apoptosis (p < 0.01), and 30% less calretinin expression (p < 0.05; a marker of neuronal differentiation) in the hippocampus compared with WT. The DHA-supplemented diet increased fetal brain Pemt-/- phospholipid-DHA to WT levels, and abrogated the neural progenitor cell proliferation and apoptosis differences. Although this diet did not change proliferation in the WT group, it halved the rate of apoptosis (p < 0.05). In both genotypes, the DHA-supplemented diet increased calretinin expression 2-fold (p < 0.05). These results suggest that the changes in hippocampal development in the Pemt-/- mouse could be mediated by altered DHA incorporation into membrane phospholipids, and that maternal dietary DHA can influence fetal brain development.
Sonnenfleckenzeichnung Nr. 72.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 06.04.2010, 08:00, erstellt von Sergio Cortesi
Creators: name: Observatorium Specola Solare Ticinese Locarno (1957 bis 1980 Teil der Eidgenössischen Sternwarte der ETH Zürich)
Publisher: name: [s.n.]
Year: 2010

description: Bleistiftzeichnung mit schwarzer Farbe und Bleistift, erstellt als Projektionsbildzeichnung für die Beobachtungen in Locarno-Monti auf einem eigenen Vordruck. Instrument: Zeiss-Coudé-Refraktor mit 15 cm Öffnung und 225 cm Brennweite. Bildqualität (SIDC): 3.
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden auf dem Vordruck eingetragen. Zusätzlich sind zuhanden der späteren statistischen Verarbeitung die Angaben für die Bestimmung der Fleckenrelativzahl notiert.
Beobachtungstätigkeit unter eigenständiger Leitung (Associazione Specola Solare Ticinese ASST)
(502223) Sarah Thomasine Younger
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.