cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Epistatic effect of TLR3 and cGAS-STING-IKKε-TBK1-IFN signaling variants on colorectal cancer risk
Creators: name: Catalano, Calogerina
name: Da Silva Filho, Miguel Inacio
name: Frank, Christoph
name: Lu, Shun
name: Jiraskova, Katerina
name: Vymetalkova, Veronika
name: Levy, Miroslav
name: Liska, Vaclav
name: Vycital, Ondrej
name: Naccarati, Alessio
name: Vodickova, Ludmila
name: Hemminki, Kari
name: Vodicka, Pavel
name: Weber, Alexander N. R.
name: Försti, Asta
Publisher: name: FID GEO
Year: 2019

description: Abstract Objective The TLR3/cGAS-STING-IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in these genes on the risk of sporadic colorectal cancer (CRC) in a Czech cohort of 1424 CRC patients and 1114 healthy controls. Methods The variants in the TLR3, CGAS, TMEM173, IKBKE, and TBK1 genes were selected using various online bioinformatic tools, such as UCSC browser, HaploReg, Regulome DB, Gtex Portal, SIFT, PolyPhen2, and miRNA prediction tools. Results Logistic regression analysis adjusted for age and sex detected a nominal association between CRC risk and three variants, CGAS rs72960018 (OR: 1.68, 95% CI: 1.11-2.53, P-value = .01), CGAS rs9352000 (OR: 2.02, 95% CI: 1.07-3.84, P-value = .03) and TMEM173 rs13153461 (OR: 1.53, 95% CI: 1.03-2.27, P-value = .03). Their cumulative effect revealed a threefold increased CRC risk in carriers of 5-6 risk alleles compared to those with 0-2 risk alleles. Epistatic interactions between these genes and the previously genotyped IFNAR1, IFNAR2, IFNA, IFNB, IFNK, IFNW, IRF3, and IRF7 genes, were computed to test their effect on CRC risk. Overall, we obtained nine pair-wise interactions within and between the CGAS, TMEM173, IKBKE, and TBK1 genes. Two of them remained statistically significant after Bonferroni correction. Additional 52 interactions were observed when IFN variants were added to the analysis. Conclusions Our data suggest that epistatic interactions and a high number of risk alleles may play an important role in CRC carcinogenesis, offering novel biological understanding for the CRC management.
Comment on new physics contributions to Gamma_{12}^s
Creators: name: Bauer, Christian W.
name: Dunn, Nicholas Daniel
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A recent measurement by the D0 collaboration finds a like-sign di-muon charge asymmetry in the B system that is roughly 3 sigma larger than the value predicated by the Standard Model. This suggests new physics contributing to B-Bbar mixing. For the current central value of the CP asymmetry, the required size of Gamma_{12}^s is larger than Standard Model estimates of this quantity. In this paper, we will explore the constraints on new physics contributions to Gamma_{12}^s. We show that there are two dimension six operators of Standard Model fields in the electroweak Hamiltonian whose coefficients are not constrained enough to rule out possible contributions from new physics. We argue that a more precise measurement of tau(B_s)/tau(B_d), which is possible with currently available data, could either support or strongly constrain the existence of new physics in Gamma_{12}^s.
description: 6 pages, 1 figure. Minor revisions and references added
Monitoring freshwater–saltwater interfaces with SAMOS – installation effects on data and inversion
Creators: name: Ronczka, Mathias
name: Günther, Thomas
name: Grinat, Michael
name: Wiederhold, Helga
Publisher: name: FID GEO
Year: 2020

description: A major problem for the freshwater supply of coastal regions is the intrusion of saltwater into aquifers. Due to extensive extraction of freshwater to suffice increasing drinking water demands and/or in periods of reduced groundwater recharge, the equilibrium state may be disturbed. The result is an upconing or movement of the fresh–saline groundwater interface, which reduces the local drinking water resources at coastal regions or islands. The saltwater monitoring system (SAMOS) is a vertical electrode chain installed in a backfilled borehole. It provides a solution to observe the transition zone in detail, both temporally and spatially. We present monitoring data of the first year from three locations - with different geological conditions that show disturbances in the resistivity distribution that result from the drilling processes. A clayey backfilling, for example, can lead to beam-like artefacts, and a mixed fluid within the backfilling changes its bulk resistivity, both leading to misinterpretations. We performed data inversion under cylindrically symmetrical conditions in full-space in order to separate these resistivity artefacts from the undisturbed background. Data inversion reveals that it is possible to separate drilling effects on the resistivity distribution from the undisturbed background. Thus, an interpretation of the natural transition zones can be made immediately after the installation.
Surface Properties of Colloidal Particles Affect Colloidal Self-Assembly in Evaporating Self-Lubricating Ternary Droplets
Creators: name: Koshkina, Olga
name: Raju, Lijun Thayyil
name: Kaltbeitzel, Anke
name: Riedinger, Andreas
name: Lohse, Detlef
name: Zhang, Xuehua
name: Landfester, Katharina
Publisher: name: arXiv
Year: 2022
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: In this work, we unravel the role of surface properties of colloidal particles on the formation of supraparticles (clusters of colloidal particles) in a colloidal Ouzo droplet. Self-lubricating colloidal Ouzo droplets are an efficient and simple approach to form supraparticles, overcoming the challenge of the coffee stain effect in situ. Supraparticles are an efficient route to high-performance materials in various fields, from catalysis to carriers for therapeutics. Yet, the role of the surface of colloidal particles in the formation of supraparticles using Ouzo droplets remains unknown. Therefore, we used silica particles as a model system and compared sterically stabilized versus electrostatically stabilized silica particles - positively and negatively charged. Additionally, we studied the effect of hydration. Hydrated negatively charged silica particles and sterically stabilized silica particles form supraparticles. Conversely, dehydrated negatively charged silica particles and positively charged amine-coated particles form flat film-like deposits. Notably, the assembly process is different for all the four types of particles. The surface modifications alter (a) the contact line motion of the Ouzo droplet and (b) the particle-oil and particle-substrate interactions. These alterations modify the particle accumulation at the various interfaces, which ultimately determines the shape of the final deposit. Thus, by modulating the surface properties of the colloidal particles, we can tune the shape of the final deposit, from a spheroidal supraparticle to a flat deposit. In the future, this approach can be used to tailor the supraparticles for applications such as optics and catalysis, where the shape affects the functionality.
description: 38 pages, 9 figures
Seismic P Wave Velocity Model From 3-D Surface and Borehole Seismic Data at the Alpine Fault DFDP-2 Drill Site (Whataroa, New Zealand)
Creators: name: Lay, V.
name: Buske, S.
name: Bodenburg, S. B.
name: Townend, J.
name: Kellett, R.
name: Savage, M. K.
name: Schmitt, D. R.
name: Constantinou, A.
name: Eccles, J. D.
name: Bertram, M.
name: Hall, K.
name: Lawton, D.
name: Gorman, A. R.
name: Kofman, R. S.
Publisher: name: FID GEO
Year: 2020

description: The New Zealand Alpine Fault is a major plate boundary that is expected to be close to rupture, allowing a unique study of fault properties prior to a future earthquake. Here we present 3-D seismic data from the DFDP-2 drill site in Whataroa to constrain valley structures that were obscured in previous 2-D seismic data. The new data consist of a 3-D extended vertical seismic profiling (VSP) survey using three-component and fiber optic receivers in the DFDP-2B borehole and a variety of receivers deployed at the surface. The data set enables us to derive a detailed 3-D P wave velocity model by first-arrival traveltime tomography. We identify a 100–460 m thick sediment layer (mean velocity 2,200 ± 400 m/s) above the basement (mean velocity 4,200 ± 500 m/s). Particularly on the western valley side, a region of high velocities rises steeply to the surface and mimics the topography. We interpret this to be the infilled flank of the glacial valley that has been eroded into the basement. In general, the 3-D structures revealed by the velocity model on the hanging wall of the Alpine Fault correlate well with the surface topography and borehole findings. As a reliable velocity model is not only valuable in itself but also crucial for static corrections and migration algorithms, the Whataroa Valley P wave velocity model we have derived will be of great importance for ongoing seismic imaging. Our results highlight the importance of 3-D seismic data for investigating glacial valley structures in general and the Alpine Fault and adjacent structures in particular.
Coupling spatially and spectrally resolved optical measurements with a scanning probe system
Creators: name: Roussy, Tanya
Publisher: name: University of British Columbia
Year: 2016

description: Developing a bottom-up understanding of the physics behind charge transfer processes on the nanometer scale will enable the focused design and synthesis of new materials which will revolutionize everything from solar cells to wearable electronics. Pushing our understanding of these processes to the nanometer scale is critical for next generation device development for two primary reasons. Firstly, modern electronic devices are fabricated ever smaller; to date IBM Research has already produced working chips using with gate widths only 14 atoms (7 nm) wide [1]. Secondly, for many devices which rely on charge transfer the important action is at the interface between materials; it is here that the energy level offset and other parameters can make or break a device. For modern organic devices, the interfacial region is in essence a nanometer-wide region: energy levels can differ by hundreds of meV only a few molecules away from an interface [2]. This thesis presents the design and execution of experiments which couple optical measurements with a scanning probe system. The marriage of optical and scanning probe systems enables simultaneous exploration of two complementary dimensions (optical and electronic) of the physics of the system under study, enabling the probing of parameters affecting charge transfer between single molecules. The custom-built system was used to explore optical and electronic properties of two prototypical organic molecules forming an acceptor-donor pair: 3,4,9,10-perylene tetracarboxylic dianhydride (PTCDA) and copper (II) pthalocyanine. This proof-of-concept will allow future users to explore a wide variety of systems which may offer clues to how charge transfer processes occur at the nanometer scale. In the first part of this work I describe the motivation for our experiment as well as the experimental design and set-up. In the second part I detail how we used the enhanced optical-electrical scanning probe to observe real-space energy levels, luminescence (or lack thereof), and attempted optical excitations between two single organic molecules. Analysis of scanning tunnelling spectroscopy data coupled with laser excitation as well as the results from experiments which in principle can measure sub-molecularly resolved luminescence show that the new optical system works as expected.
The Methodology of Geometric Order in the Design of Traditional Islamic Buildings - A Case Study of Madrasas in the Mamluk Eras in Egypt
Creators: name: Gaber, Ahmed Ali Ahmed
Publisher: name: Karlsruhe
Year: 2011
Subjects: subject: Architecture
subject: FOS: Civil engineering
subject: Geometry
subject: Design
subject: Mamluk
subject: Madrasa

description: The research focuses on the relation between architecture design and geometry. The research started a process of geometric decoding for Mamluk madrasas beginning with demonstrating the geometric methodology of design, trying to blow away the dust from above the layer of geometry in Mamluk architecture. It ends with suggesting a geometric generative technique for madrasa building design and demonstrates a computer-aided generator program.
Pingpong-Energietransfer in kovalent verknüpften Porphyrin-MoS2-Architekturen
Creators: name: Canton-Vitoria, Ruben
name: Scharl, Tobias
name: Stergiou, Anastasios
name: Cadranel, Alejandro
name: Arenal, Raul
name: Guldi, Dirk M.
name: Tagmatarchis, Nikos
Publisher: name: FID GEO
Year: 2020

description: Abstract Molybdändisulfid-Nanoschichten wurden mit Porphyrin kovalent modifiziert und vollständig charakterisiert. Weder die Porphyrin-Absorption noch die Fluoreszenz wurden durch die kovalente Bindung an MoS2 merklich beeinflusst. Mithilfe transienter Absorptionsspektroskopie konnte jedoch ein komplexer Pingpong-Energietransfer-Mechanismus, nämlich vom Porphyrin zum MoS2 und wieder zurück zum Porphyrin, bestätigt werden. Diese Studie zeigt das Potential von Übergangsmetalldichalkogeniden bei Photosensibilisierungsprozessen auf.
Threshold Corrections in Grand Unified Theories
Creators: name: Martens, Waldemar
Publisher: name: Karlsruhe
Year: 2011
Subjects: Grand Unified Theory
Supersymmetry
Renormalization Group
Threshold Correction
Group Theory
Multiloop

description: We perfrom a state-of-the-art gauge coupling unification analysis for two simple supersymmetric GUT model. We find that in Minimal Supersymmetric SU(5) three-loop effects raise the mass of the colored Higgs triplet by one order of magnitude, attenuating presumed tension with the proton decay bound. In a second part of the thesis, we calculate the yet missing two-loop GUT threshold corrections in the simplest GUT model, the Georgi-Glashow SU(5) and give many technical details of the calculation.
Generalized Froggatt-Nielsen Mechanism
Creators: name: Wang, Fei
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In this paper, we propose a Generalized Froggatt-Nielsen mechanism in which non-renormalizable operators involving a GUT group and $U(1)_H$ non-singlet Higgs field are introduced. Thus the GUT gauge symmetry breaking and the generation of hierarchical flavor hierarchy have a common origin in this mechanism. In this Generalized Froggatt-Nielsen mechanism, we propose universality conditions for coefficients corresponding to different contractions in the group productions. We find that the predictions in Generalized Froggatt-Nielsen mechanism for SU(5) GUT is different to that of ordinary Froggatt-Nielsen mechanism. Such Generalized Froggatt-Nielsen mechanism can be used in GUT models when ordinary Froggatt-Nielsen mechanism is no longer available. We study the application of Generalized Froggatt-Nielsen mechanism in SO(10) model. We find that realistic standard model mass hierarchy and mixings can be obtained both in SU(5) and SO(10) GUT models with such Generalized Froggatt-Nielsen mechanism.
description: 4 pages, no figures
Aerosol-Cloud-Precipitation Interactions in the Context of Convective Self-Aggregation
Creators: name: Beydoun, H.
name: Hoose, C.
Publisher: name: FID GEO
Year: 2019

description: We investigate the sensitivity of self-aggregated radiative-convective-equilibrium cloud-resolving model simulations to the cloud condensation nuclei (CCN) concentration. Experiments were conducted on a long (2,000-km × 120-km) channel domain, allowing the emergence of multiple convective clusters and dry regions of subsidence. Increasing the CCN concentration leads to increased moisture in the dry regions, increased midlevel and upper level clouds, decreased radiative cooling, and decreased precipitation. We find that these trends follow from a decrease in the strength of the self-aggregation as measured by the moist static energy (MSE) variance. In our simulations, precipitation is correlated, both locally and in total, with the distribution of MSE anomalies. We thus quantify changes in the adiabatic/diabatic contributions to MSE anomalies (Wing & Emanuel, 2014, https://doi.org/10.1002/2013MS000269) and relate those changes to changes in precipitation. Through a simple two-column conceptual model, we argue that the reduction in precipitation can be explained thermodynamically by the reduction in mean net radiative cooling and mechanistically by the weakening of the area-weighted radiatively driven subsidence velocity—defined as the ratio of the total radiative cooling over the dry regions and the static stability. We interpret the system's response to increasing CCN as a thermodynamically constrained realization of an aerosol indirect effect on clouds and precipitation.
Agricultural-Food Policy Review: U.S. Agricultural Policies in a Changing World
Creators: name: Economic Research Service
name: Economic Research Service
Publisher: name: Unknown
Year: 1989
Subjects: Agricultural and Food Policy

description: This review brings together background information for assessing today's agricultural sector and the programs of the Food Security Act of 1985 and for looking to the future for new agricultural, environmental, and rural development issues. This information sets the stage for debating omnibus agricultural and rural development legislation to take effect when the 1985 Act expires in 1990.
Sanitätsrat Dr. Franz Piesbergen ✝
Creators: name: Reihlen, Max
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1928

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 84, 1928
Heavy-Quark Diffusion and Hadronization in Quark-Gluon Plasma
Creators: name: He, Min
name: Fries, Rainer J.
name: Rapp, Ralf
Publisher: name: arXiv
Year: 2011
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We calculate diffusion and hadronization of heavy quarks in high-energy heavy-ion collisions implementing the notion of a strongly coupled quark-gluon plasma in both micro- and macroscopic components. The diffusion process is simulated using relativistic Fokker-Planck dynamics for elastic scattering in a hydrodynamic background. The heavy-quark transport coefficients in the medium are obtained from non-perturbative $T$-matrix interactions which build up resonant correlations close to the transition temperature. The latter also form the basis for hadronization of heavy quarks into heavy-flavor mesons via recombination with light quarks from the medium. The pertinent resonance recombination satisfies energy conservation and provides an equilibrium mapping between quark and meson distributions. The recombination probability is derived from the resonant heavy-quark scattering rate. Consequently, recombination dominates at low transverse momentum ($p_T$) and yields to fragmentation at high $p_T$. Our approach thus emphasizes the role of resonance correlations in the diffusion and hadronization processes. We calculate the nuclear modification factor and elliptic flow of $D$- and $B$-mesons for Au-Au collisions at the Relativistic Heavy Ion Collider, and compare their decay-electron spectra to available data. We also find that a realistic description of the medium flow is essential for a quantitative interpretation of the data.
description: 16 pages, 14 figures
Yellow Supergiants in the Small Magellanic Cloud (SMC): Putting Current Evolutionary Theory to the Test
Creators: name: Neugent, Kathryn F.
name: Massey, Philip
name: Skiff, Brian
name: Drout, Maria R.
name: Meynet, Georges
name: Olsen, Knut A. G.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The yellow supergiant content of nearby galaxies provides a critical test of massive star evolutionary theory. While these stars are the brightest in a galaxy, they are difficult to identify because a large number of foreground Milky Way stars have similar colors and magnitudes. We previously conducted a census of yellow supergiants within M31 and found that the evolutionary tracks predict a yellow supergiant duration an order of magnitude longer than we observed. Here we turn our attention to the SMC, where the metallicity is 10x lower than that of M31, which is important as metallicity strongly affects massive star evolution. The SMC's large radial velocity (~160 km/s) allows us to separate members from foreground stars. Observations of ~500 candidates yielded 176 near-certain SMC supergiants, 16 possible SMC supergiants, along with 306 foreground stars and provide good relative numbers of yellow supergiants down to 12Mo. Of the 176 near-certain SMC supergiants, the kinematics predicted by the Besancon model of the Milky Way suggest a foreground contamination of >4%. After placing the SMC supergiants on the H-R diagram and comparing our results to the Geneva evolutionary tracks, we find results similar to those of the M31 study: while the locations of the stars on the H-R diagram match the locations of evolutionary tracks well, the models over-predict the yellow supergiant lifetime by a factor of ten. Uncertainties about the mass-loss rates on the main-sequence thus cannot be the primary problem with the models.
description: Accepted by the ApJ
π-Conjugation Enables Ultra-High Rate Capabilities and Cycling Stabilities in Phenothiazine Copolymers as Cathode-Active Battery Materials
Creators: name: Acker, Pascal
name: Rzesny, Luisa
name: Marchiori, Cleber F. N.
name: Araujo, C. Moyses
name: Esser, Birgit
Publisher: name: FID GEO
Year: 2019

description: Abstract In recent years, organic battery cathode materials have emerged as an attractive alternative to metal oxide–based cathodes. Organic redox polymers that can be reversibly oxidized are particularly promising. A drawback, however, often is their limited cycling stability and rate performance in a high voltage range of more than 3.4 V versus Li/Li+. Herein, a conjugated copolymer design with phenothiazine as a redox-active group and a bithiophene co-monomer is presented, enabling ultra-high rate capability and cycling stability. After 30 000 cycles at a 100C rate, >97% of the initial capacity is retained. The composite electrodes feature defined discharge potentials at 3.6 V versus Li/Li+ due to the presence of separated phenothiazine redox centers. The semiconducting nature of the polymer allows for fast charge transport in the composite electrode at a high mass loading of 60 wt%. A comparison with three structurally related polymers demonstrates that changing the size, amount, or nature of the side groups leads to a reduced cell performance. This conjugated copolymer design can be used in the development of advanced redox polymers for batteries.
Die Berechnung der Eiszeiten auf astronomisch-physikalischer Grundlage
Creators: name: Pilgrim, Ludwig Johann Heinrich
name: Wundt, Walter
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1928

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 84, 1928
20_Schmidpeter_2020_NatCommun.pdf
Creators: name: Schmidpeter, Philipp A. M.
name: Rheinberger, Jan
name: Nimigean, Crina M.
Publisher: name: Health Research Alliance
Year: 2020
Subjects: Biophysics
Structural Biology

description: SthK, a cyclic nucleotide-modulated ion channel from Spirochaeta thermophila, activates slowly upon cAMP increase. This is reminiscent of the slow, cAMP-induced activation reported for the hyperpolarization-activated and cyclic nucleotide-gated channel HCN2 in the family of so-called pacemaker channels. Here, we investigate slow cAMP-induced activation in purified SthK channels using stopped-flow assays, mutagenesis, enzymatic catalysis and inhibition assays revealing that the cis/trans conformation of a conserved proline in the cyclic nucleotide-binding domain determines the activation kinetics of SthK. We propose that SthK exists in two forms: trans Pro300 SthK with high ligand binding affinity and fast activation, and cis Pro300 SthK with low affinity and slow activation. Following channel activation, the cis/trans equilibrium, catalyzed by prolyl isomerases, is shifted towards trans, while steady-state channel activity is unaffected. Our results reveal prolyl isomerization as a regulatory mechanism for SthK, and potentially eukaryotic HCN channels. This mechanism could contribute to electrical rhythmicity in cells.
Direkte Mechanokatalyse: Palladium als Mahlmaterial und Katalysator in der mechanochemischen Suzuki-Polymerisation
Creators: name: Vogt, Christian G.
name: Grätz, Sven
name: Lukin, Stipe
name: Halasz, Ivan
name: Etter, Martin
name: Evans, Jack D.
name: Borchardt, Lars
Publisher: name: FID GEO
Year: 2019

description: Abstract Das Mahlmaterial ist der Katalysator. In diesem Beitrag stellen wir eine palladiumkatalysierte Reaktion in der Kugelmühle vor, bei der weder Katalysatorpulver, Liganden, noch Lösungsmittel verwendet werden. Dieses einfache und nachhaltige Konzept zeigen wir am Beispiel der Suzuki-Polymerisation von 4-Brom- bzw. 4-Iodphenylboronsäure zu Poly(para-phenylen). Überdies beobachten wir einen der höchsten bisher publizierten Polymerisationsgrade (199).
Connectivity in Sub-Poisson Networks
Creators: name: Blaszczyszyn, Bartlomiej
name: Yogeshwaran, D.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Probability (math.PR)
subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Mathematics
subject: FOS: Computer and information sciences

description: We consider a class of point processes (pp), which we call {\em sub-Poisson}; these are pp that can be directionally-convexly ($dcx$) dominated by some Poisson pp. The $dcx$ order has already been shown useful in comparing various point process characteristics, including Ripley's and correlation functions as well as shot-noise fields generated by pp, indicating in particular that smaller in the $dcx$ order processes exhibit more regularity (less clustering, less voids) in the repartition of their points. Using these results, in this paper we study the impact of the $dcx$ ordering of pp on the properties of two continuum percolation models, which have been proposed in the literature to address macroscopic connectivity properties of large wireless networks. As the first main result of this paper, we extend the classical result on the existence of phase transition in the percolation of the Gilbert's graph (called also the Boolean model), generated by a homogeneous Poisson pp, to the class of homogeneous sub-Poisson pp. We also extend a recent result of the same nature for the SINR graph, to sub-Poisson pp. Finally, as examples we show that the so-called perturbed lattices are sub-Poisson. More generally, perturbed lattices provide some spectrum of models that ranges from periodic grids, usually considered in cellular network context, to Poisson ad-hoc networks, and to various more clustered pp including some doubly stochastic Poisson ones.
description: 8 pages, 10 figures, to appear in Proc. of Allerton 2010. For an extended version see http://hal.inria.fr/inria-00497707 version 1
Tradable Development Certificates in Germany - A Theoretical and Empirical Analysis
Creators: name: Müller, Jens E.
Publisher: name: Karlsruhe
Year: 2011
Subjects: Flächenausweisungszertifikate
Tradable Development Certificates
Landnutzung
Land Usage
Market Design

description: In der Dissertation wird das Design eines Systems mit Flächenausweisungszertifikaten vorgestellt und mit empirischen Daten evaluiert, die im Rahmen eines Feldexperiments mit kommunalen Entscheidungsträgern erhoben wurden. Die Ergebnisse zeigen wie ein solches Handelssystem für Flächenausweisungszertifikate in der Praxis gestaltet werden kann und welche Herausforderungen und Grenzen für den praktischen Einsatz des neuen Instrumentes zur Flächenverbrauchsreduktion bestehen.
Analysis on the Influencing Factors and Control Measures of "Non-Grain Conversion" of Cultivated Land in Agricultural Land Transfer
Creators: name: XIA Lixian
name: YANG Zisheng
name: XIA Lixian
name: YANG Zisheng
Publisher: name: Unknown
Year: 2021
Subjects: subject: Agribusiness
subject: Agricultural land transfer, Non-grain conversion of cultivated land, Food security, Influencing factors, Measures

description: Through the method of literature analysis, this paper analyzes the present situation of the "non-grain conversion" of cultivated land in the transfer of agricultural land in China, summarizes the influencing factors and consequences of the phenomenon of "non-grain conversion" of cultivated land in the transfer of agricultural land, and finally puts forward some measures. The study found that costs and benefits are the fundamental factors affecting the "non-grain conversion" of cultivated land in agricultural land transfer, and other main factors include government and policy guidance, industrial and commercial capital to the countryside, labor transfer and so on. The "non-grain conversion" of cultivated land in the transfer of agricultural land is a serious threat to China's food security, leading to the decline of the quality of agricultural land and the destruction of the ecological environment, as well as the risk of breach of contract in "industrial and commercial capital to the countryside". Based on the understanding of the influencing factors of non-grain conversion, this paper puts forward the following measures: strengthening the control of the use of cultivated land in agricultural land transfer; implementing accurate subsidies for grain cultivation and ensuring the benefit of grain growers; adopting grain planting incentive mechanism to increase grain enthusiasm; strengthening media publicity and education to enhance food security awareness. The improvement of the current situation of the "non-grain conversion" of cultivated land in the transfer of agricultural land will be of great significance to the protection of agricultural land and food security in China.
Entwicklung eines partikelbasierten Verfahrens für den parallelen Nachweis von Proteinen
Creators: name: Theilacker, Nora
Publisher: name: Karlsruhe
Year: 2011
Subjects: Magnetpartikel
Multiplex
Proteinnachweis
Kodierung

description: In dieser Arbeit wurde ein auf fluoreszenzkodierten Mikropartikeln basiertes Multiplex-Verfahren für den gleichzeitigen Nachweis mehrerer Krankheitsmarker entwickelt. Die Krankheitsmarker werden mittels fluoreszenzmarkierter Antikörper detektiert. Dekodierung der Partikel und Quantifizierung der Proteine erfolgen fluoreszenzmikroskopisch. Es wurde gezeigt, dass mindestens 4 Krankheitsmarker im klinisch relevanten Bereich nachgewiesen werden können.
Ein neuer Aufschluß an der Keuper-Liasgrenze
Creators: name: Haag, Friedrich
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1928

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 84, 1928
Facile C=O Bond Splitting of Carbon Dioxide Induced by Metal–Ligand Cooperativity in a Phosphinine Iron(0) Complex
Creators: name: Leitl, Julia
name: Marquardt, Michael
name: Coburger, Peter
name: Scott, Daniel J.
name: Streitferdt, Verena
name: Gschwind, Ruth M.
name: Müller, Christian
name: Wolf, Robert
Publisher: name: FID GEO
Year: 2019

description: Abstract New iron complexes [Cp*FeL]− (1-σ and 1-π, Cp*=C5Me5) containing the chelating phosphinine ligand 2-(2′-pyridyl)-4,6-diphenylphosphinine (L) have been prepared, and found to undergo facile reaction with CO2 under ambient conditions. The outcome of this reaction depends on the coordination mode of the versatile ligand L. Interaction of CO2 with the isomer 1-π, in which L binds to Fe through the phosphinine moiety in an η5 fashion, leads to the formation of 3-π, in which CO2 has undergone electrophilic addition to the phosphinine group. In contrast, interaction with 1-σ—in which L acts as a σ-chelating [P,N] ligand—leads to product 3-σ in which one C=O bond has been completely broken. Such CO2 cleavage reactions are extremely rare for late 3d metals, and this represents the first such example mediated by a single Fe centre.
Iron-porphyrin Catalyzed Carbene Transfer Reactions – an Evolution from Biomimetic Catalysis towards Chemistry-inspired Non-natural Reactivities of Enzymes
Creators: name: Weissenborn, Martin J.
name: Koenigs, Rene M.
Publisher: name: FID GEO
Year: 2020

description: Abstract Bioinspired, synthetic porphyrin complexes are important catalysts in organic synthesis and play a pivotal role in efficient carbene transfer reactions. The advances in this research area stimulated recent, “chemo-inspired” developments in biocatalysis. Today, both synthetic iron complexes and enzymes play an important role to conduct carbene transfer reactions. The advances and potential developments in both research areas are discussed in this concept article.
Merging Top-Down and Bottom-Up Approaches to Fabricate Artificial Photonic Nanomaterials with a Deterministic Electric and Magnetic Response
Creators: name: Dietrich, Kay
name: Zilk, Matthias
name: Steglich, Martin
name: Siefke, Thomas
name: Hübner, Uwe
name: Pertsch, Thomas
name: Rockstuhl, Carsten
name: Tünnermann, Andreas
name: Kley, Ernst-Bernhard
Publisher: name: FID GEO
Year: 2019

description: Abstract Artificial photonic nanomaterials made from densely packed scatterers are frequently realized either by top-down or bottom-up techniques. While top-down techniques offer unprecedented control over achievable geometries for the scatterers, by trend they suffer from being limited to planar and periodic structures. In contrast, materials fabricated with bottom-up techniques do not suffer from such disadvantages but, unfortunately, they offer only little control on achievable geometries for the scatterers. To overcome these limitations, a nanofabrication strategy is introduced that merges both approaches. A large number of scatterers are fabricated with a tailored optical response by fast character projection electron-beam lithography and are embedded into a membrane. By peeling-off this membrane from the substrate, scrambling, and densifying it, a bulk material comprising densely packed and randomly arranged scatterers is obtained. The fabrication of an isotropic material from these scatterers with a strong electric and magnetic response is demonstrated. The approach of this study unlocks novel opportunities to fabricate nanomaterials with a complex optical response in the bulk but also on top of arbitrarily shaped surfaces.
Molecular dynamics simulations of heterogeneous ice nucleation by atmospheric aerosols
Creators: name: Zielke, Stephen Alexander
Publisher: name: University of British Columbia
Year: 2016

description: Water droplets in the atmosphere do not freeze homogeneously until -38ºC. Freezing at warmer temperatures requires heterogeneous ice nuclei (IN). Despite the importance of ice in the atmosphere, little is known about the microscopic mechanisms of heterogeneous ice nucleation. This thesis employs molecular dynamics simulations to investigate ice nucleation by silver iodide, kaolinite, potassium feldspar, gibbsite, and a protein. Silver iodide is one of the best known ice nucleating agents. We examined seven surfaces of silver iodide and observed ice nucleation on three surfaces. The surfaces that nucleated ice organized the first layer of water molecules into a configuration resembling ice, such as chair conformed hexagonal rings. Surfaces that do not nucleate ice do not organize water into icelike configurations, such as planar rings. Results suggest lattice mismatch is insufficient in predicting ice nucleation, and a finer atomistic match is required. Finite silver iodide disks and plates were used to probe the relationship between the size of a nucleating surface and maximum temperature of ice nucleation. Larger disks nucleated ice at warmer temperatures than smaller disks by forming larger initial cluster of ice which could reach the critical size easier than homogeneously formed clusters. Kaolinite is a common clay known to nucleate ice. Our simulations investigated both sides of the (001) surface and found both sides able to nucleate ice. The Al-surface was simulated with varying degrees of freedom of motion. An optimum amount of movement was required to nucleate ice as the surface needs to adapt into a configuration favorable to ice. Ice nucleated on the Si-surface via the formation of a novel composite surface structure which facilitated bulk ice nucleation. Potassium feldspar simulations explored three variations of the two primary cleavage planes. All surfaces failed to nucleate ice and density profiles suggest that the surfaces are unlikely to nucleate ice. We succeeded in nucleating ice on gibbsite with prepared surface conformations compatible with ice. Biological IN, such as ice nucleation proteins, are among the most efficient IN. We attempted to simulate ice nucleation via a protein, but were unable to achieve ice nucleation.
Zur Stratigraphie und Paläogeographie des Wellengebirges im südlichen Schwarzwald
Creators: name: Frank, Manfred
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1928

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 84, 1928
Complex and real unconventional Bose-Einstein condensations in high orbital bands
Creators: name: Cai, Zi
name: Wu, Congjun
Publisher: name: arXiv
Year: 2011
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Other Condensed Matter (cond-mat.other)
subject: FOS: Physical sciences

description: We perform the theoretical study on the unconventional Bose-Einstein condensations (UBEC) in the high bands of optical lattices observed by Hemmerich's group. These exotic states are characterized by complex-valued condensate wavefunctions with nodal points, or real-valued ones with nodal lines, thus are beyond the {\it "no-node"} paradigm of the conventional BECs. A quantum phase transition is driven by the competition between the single particle band and interaction energies. The complex UBECs spontaneously break time-reversal symmetry, exhibiting a vortex-antivortex lattice structure.
description: 4.2 pages
Über ein Bohrloch bei Hochdorf OA. Horb
Creators: name: Wagner, Georg
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1928

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 84, 1928
Progressive damage analysis of embedment of metal washer into timber
Creators: name: Teranishi, Masaki
name: Matsubara, Doppo
Publisher: name: Taylor & Francis
Year: 2024
Subjects: subject: Biophysics
subject: Physiology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified

description: Metal washers are widely used in joints of timber structures. Thick washers embed fully into timber, whereas thin washers partially embed into timber due to their bending deformation. For thick washers, physical models have been proposed to estimate the stiffness and strength of timber. However, for thin washers, these estimation methods are insufficient. The objective of this study is to propose a finite-element analysis (FEA)-based approach to predict the stiffness and strength of wood during washer embedding, as well as forecast plasticity and damage behaviours of timber, regardless of the washer size. The FEA used a constitutive model with plastic and damage criteria for timber. In the FEA, an explicit dynamic solution method was used to prevent solution divergence. The FEA reproduced the embedment load–displacement relation and damage behaviours of three species. In addition, the FEA predicted the initial stiffness, second stiffness, and yield load with error margins of 12%, 16%, and 7%, respectively. The influences of the loading speed and mesh fineness on the FEA were investigated numerically to validate the results. In addition, parametric studies on contact stiffness and damage constants were conducted to understand the influences of material constants on the embedment behaviours of FE models.
Seismic prediction ahead of tunnel construction using Rayleigh-waves
Creators: name: Jetschny, Stefan
name: De Nil, Denise
name: Bohlen, Thomas
Publisher: name: Karlsruhe
Year: 2008

description: To increase safety and efficiency of tunnel constructions, online seismic exploration ahead of a tunnel can become a valuable tool. We developed a new forward looking seismic imaging technique e.g. to determine weak and water bearing zones ahead of the constructions. Our approach is based on the excitation and registration of tunnel surface-waves. These waves are excited at the tunnel face behind the cutter head of a tunnel boring machine and travel into drilling direction. Arriving at the front face they generate body-waves propagating further ahead. Reflected S-waves are back-converted into tunnel surface-waves.
Predictors of survival in patients with acute coronary syndrome undergoing percutaneous coronary intervention of unprotected left main coronary artery stenosis
Creators: name: Staudacher, Dawid L.
name: Schmitt, Charlotte
name: Zirlik, Andreas
name: Zehender, Manfred
name: Stachon, Peter
name: Bothe, Wolfgang
name: Zotzmann, Viviane
name: Bode, Christoph
name: Von Zur Muehlen, Constantin
Publisher: name: FID GEO
Year: 2019

description: Abstract Objective Aim of this study was to investigate predictors of survival in unstable patients with high SYNTAX-1-score. Background In significant unprotected left main coronary artery (ULMCA) stenosis, treatment options include percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG). While CABG is recommended for stable patients with ULMCA stenosis and a SYNTAX-1-score > 32, PCI may be preferable in unstable or high operative risk patients. Methods Retrospective single-center all-comers registry study. Results A total of 142 patients underwent ULMCA-PCI (~72.9 years, 23.2% females, 54.2% survival in 2-year follow-up), 84 of whom had a SYNTAX-1 > 32 (37.4 ± 12.8). Patients in the high-SYNTAX-1-group (score > 32) were more often in an acute condition compared to low-SYNTAX-2-group (score ≤ 32) including acute myocardial infarction (76.2% vs. 57.4%, p = .024), cardiogenic shock (48.2% vs. 14.8%, p = .001), or need for mechanical support (36.1% vs. 11.1%, p = .001). Survival was predicted by the acute condition including cardiogenic shock (OR 0.06 and 0.05) and myocardial infarction (OR 0.03 and 0.34) in both groups. Performance of the SYNTAX-1-score was limited in our patient collective in both groups (c-index 0.65 vs. 0.63) while SYNTAX-2-PCI-score performed better (c-index 0.67 vs. 0.67). EuroScore II had the best discriminative ability (c-index 0.87 vs. 0.78). Conclusions The majority of patients undergoing ULMCA-PCI presented in acute conditions with high SYNTAX-1-score, and is therefore underrepresented in clinical trials. Prognosis was best predicted by the acute condition and the EuroScore II. These data suggest that therapy in unstable patients should be guided by clinical condition over the anatomical SYNTAX-1-score.
The Transit Light Curve project. XIV. Confirmation of Anomalous Radii for the Exoplanets TrES-4b, HAT-P-3b, and WASP-12b
Creators: name: Chan, Tucker
name: Ingemyr, Mikael
name: Winn, Joshua N.
name: Holman, Matthew J.
name: Sanchis-Ojeda, Roberto
name: Esquerdo, Gil
name: Everett, Mark
Publisher: name: arXiv
Year: 2011
Subjects: subject: Earth and Planetary Astrophysics (astro-ph.EP)
subject: FOS: Physical sciences

description: We present transit photometry of three exoplanets, TrES-4b, HAT-P-3b, and WASP-12b, allowing for refined estimates of the systems' parameters. TrES-4b and WASP-12b were confirmed to be "bloated" planets, with radii of 1.706 +/- 0.056 R_Jup and 1.736 +/- 0.092 R_Jup, respectively. These planets are too large to be explained with standard models of gas giant planets. In contrast, HAT-P-3b has a radius of 0.827 +/- 0.055 R_Jup, smaller than a pure hydrogen-helium planet and indicative of a highly metal-enriched composition. Analyses of the transit timings revealed no significant departures from strict periodicity. For TrES-4, our relatively recent observations allow for improvement in the orbital ephemerides, which is useful for planning future observations.
description: AJ, in press [11 pages]; corrected error in distance to WASP-12
From Research to Regulated Software
Creators: name: Kämpf, Christoph
name: Scholz, Alexander
name: Kreuz, Markus
name: Reiche, Kristin
Publisher: name: Zenodo
Year: 2023

description: We develop computational and omic-wide methods to identify and validate new biomarkers for personalised diagnosis and prognosis of diseases. Before these methods can be used in patient care they have to be implemented as regulated software. Regulated software is software that has to conform to some legislation. Legislation requires software development to be conform to IEC/ISO standards.
 We have a software that is intended to be used as a in-vitro diagnostic. So we had to establish an IEC 62304 conform software development process. Here we share some insights about: our tool stack, our processes, handling a lot of documents and how it all links to software engineering best practices and reproducible science.
Instantaneous Shape Sampling - a model for the $γ$-absorption cross section of transitional nuclei
Creators: name: Bentley, I.
name: Brant, S.
name: Doenau, F.
name: Frauendorf, S.
name: Kampfer, B.
name: Schwengner, R.
name: Zhang, S.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: The influence of the quadrupole shape fluctuations on the dipole vibrations in transitional nuclei is investigated in the framework of the Instantaneous Shape Sampling Model, which combines the Interacting Boson Model for the slow collective quadrupole motion with the Random Phase Approximation for the rapid dipole vibrations. Coupling to the complex background configurations is taken into account by folding the results with a Lorentzian with an energy dependent width. The low-energy energy portion of the $γ$- absorption cross section, which is important for photo-nuclear processes, is studied for the isotopic series of Kr, Xe, Ba, and Sm. The experimental cross sections are well reproduced. The low-energy cross section is determined by the Landau fragmentation of the dipole strength and its redistribution caused by the shape fluctuations. Collisional damping only wipes out fluctuations of the absorption cross section, generating the smooth energy dependence observed in experiment. In the case of semi-magic nuclei, shallow pygmy resonances are found in agreement with experiment.