cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Η στροφή των επιχειρήσεων στο διαδικτυακό μάρκετινγκ και η δύναμη του στα πλαίσια της οικονομικής κρίσης
title: Turn of business into internet marketing and its power in the context of the economic crisis
titleType: AlternativeTitle
Creators: name: Σαρρή, Ελένη
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2019
Subjects: subject: Διαδικτυακό μάρκετινγκ
subject: Οικονομική κρίση
subject: Διαφήμιση
subject: Επιχειρήσεις

description: Η παρούσα εργασία έχει θέμα «Η στροφή των επιχειρήσεων στο διαδικτυακό μάρκετινγκ και η δύναμη του στα πλαίσια της οικονομικής κρίσης» και αποτελείται από τέσσερα κεφάλαια. Στο πρώτο κεφάλαιο αναλύεται το διαδικτυακό μάρκετινγκ, δίνεται ο ορισμός του και μια σύντομη ιστορική εξέλιξη. Στη συνέχεια περιγράφονται οι διακρίσεις του σύγχρονου μάρκετινγκ, το μάρκετινγκ mix και οι στρατηγικές του διαδικτυακού μάρκετινγκ. Επίσης, αναλύονται οι προκλήσεις και οι ευκαιρίες καθώς και τα πλεονεκτήματα και τα μειονεκτήματά του και πραγματοποιείται μία σύγκριση του διαδικτυακού μάρκετινγκ με το παραδοσιακό μάρκετινγκ. Στο δεύτερο κεφάλαιο αναλύεται η οικονομική κρίση και περιγράφεται η οικονομική κρίση στην Ευρώπη και στην Ελλάδα. Στη τρίτο κεφάλαιο δίνεται ένας σύντομος ορισμός της επιχείρησης και αναλύονται οι επιχειρήσεις στην Ελλάδα. Έπειτα αναλύονται οι επιπτώσεις της οικονομικής κρίσης στις επιχειρήσεις, στις μικρές επιχειρήσεις και στη συνέχεια στις ελληνικές επιχειρήσεις και στις ελληνικές μικρομεσαίες επιχειρήσεις. Στο τέταρτο και τελευταίο κεφάλαιο αναλύονται οι επιχειρήσεις σε σχέση με το διαδικτυακό μάρκετινγκ. Περιγράφεται ο στρατηγικός σχεδιασμός του διαδικτυακού μάρκετινγκ και το διαδικτυακό μάρκετινγκ των επιχειρήσεων με τη χρήση μέσω κοινωνικής δικτύωσης. Αναλύεται επίσης η αποτελεσματικότητα του διαδικτυακού μάρκετινγκ και περιγράφονται κάποιες έρευνες σχετικά με το διαδικτυακό μάρκετινγκ. Στο τέλος της εργασίας υπάρχει το συμπέρασμα και οι βιβλιογραφικές αναφορές.
GLOBAL INVENTORY OF WETLANDS AND THEIR ROLE IN THE CARBON CYCLE
Creators: name: Mitra, Sudip
name: Wassmann, Reiner
name: Vlek, Paul L.G.
name: Mitra, Sudip
name: Wassmann, Reiner
name: Vlek, Paul L.G.
Publisher: name: Unknown
Year: 2003
Subjects: Environmental Economics and Policy
Land Economics/Use

description: Wetlands are among the most important natural resources on earth, as sources of biological, cultural and economic diversity. Conservation and management of wetlands have been identified as priority tasks for action in international conventions and regional policies, but extensive wetland area has been degraded in many developing countries. These continuing destruction demands to be restricted or at least slowed down. The primary objectives of this study were (i) assessing ecological functions and concepts for sustainable use of wetlands and (ii) compiling relevant information sources on geographic distribution of wetlands as well as their role in the global carbon budget. Wetlands comprise a pivotal global carbon reservoir and can moreover sequester additional carbon from the atmosphere in form of soil organic matter. Pristine wetland soils are a source of the greenhouse gas methane, but- under improper management - these soils emit even larger quantities of the greenhouse gas carbon dioxide. The discussion on wetland protection measures is thwarted by uncertainties in the estimated carbon pool sizes and flux rates. On the global scale, the estimates on the carbon pool size vary from 200 to 530 Gt C while our own assessment (by incorporating global soil maps) clearly points towards the lower end of this range. Likewise, estimates of the carbon sequestration potential of wetlands vary between 80 to 230 Tg C/ yr. These discrepancies may in part be due to inherent problems in global land cover surveys, but diverging definitions of the ecosystem 'wetlands' (especially in dealing with peatlands) are further confounding an appraisal of global wetland resources. Similar uncertainties as for the global estimates arise for the geographic distribution of wetlands as described in different data sources. The three published world maps on wetland resources only coincide in 20-30 % of the identified wetland area. Our compilation of data on quantity and distribution of the wetland carbon pool allows an identification of potential 'hot spots' of future emissions and could feed into development of research and conservation projects. There are many reasons in favor of protection or a 'wise use' of wetlands that maintains the basic features of the ecosystem. The significance of wetlands for the global carbon budget and thus, for climate change, is a crucial pro-conservation argument that has been substantiated in this study through findings from current research.
Generalized Crewther relation and a novel demonstration of the scheme independence of commensurate scale relations up to all orders
Creators: name: Huang, Xu-Dong
name: Wu, Xing-Gang
name: Yu, Qing
name: Zheng, Xu-Chang
name: Zeng, Jun
name: Shen, Jian-Ming
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the paper, we make a detailed study on the generalized Crewther Relation (GCR) between the Adler function ($D$) and the Gross-Llewellyn Smith sum rules coefficient ($C^{\rm GLS}$) by using the newly suggested single-scale approach of the principle of maximum conformality (PMC). The resultant GCR is scheme-independent, whose residual scale dependence due to unknown higher-order terms are highly suppressed. Thus a precise test of QCD theory without renormalization scheme and scale ambiguities can be achieved by comparing with the data. Moreover, a demonstration of the scheme independence of commensurate scale relation up to all orders has been presented. And as the first time, the Pade approximation approach has been adopted for estimating the unknown $5_{\rm th}$-loop contributions from the known four-loop perturbative series.
description: 8 pages, 2 figures
[Brev til DKNVS]
Creators: name: Vibe, Frederik Ludvig
name: Det Kongelige Norske Videnskabers Selskab (DKNVS)
Publisher: name: Unknown
Year: 1844

description: Meddeler at det akademiske kollegium ikke kan anta VS' bud på 150 Rdr for dubletter av antikke mynter m.m.
Antimalarial and antimicrobial activities of 8-aminoquinoline-uracils metal complexes
Creators: name: Phopin, Kamonrat
name: Sinthupoom, Nujarin
name: Treeratanapiboon, Lertyot
name: Kunwittaya, Sarun
name: Prachayasittikul, Supaluk
name: Ruchirawat, Somsak
name: Prachayasittikul, Virapong
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: aminoquinoline
subject: metal complexes
subject: uracils
subject: antimicrobial
subject: antimalarial
subject: 610

description: 8-Aminoquinoline (8AQ) derivatives have been reported to have antimalarial, anticancer, and antioxidant activities. This study investigated the potency of 8AQ-5-substituted (iodo and nitro) uracils metal (Mn, Cu, Ni) complexes (1-6) as antimalarial and antimicrobial agents. Interestingly, all of these metal complexes (1-6) showed fair antimalarial activities. Moreover, Cu complexes 2 (8AQ-Cu-5Iu) and 5 (8AQ-Cu-5Nu) exerted antimicrobial activities against Gram-negative bacteria including P. shigelloides and S. dysenteriae. The results reveal application of 8AQ and its metal complexes as potential compounds to be further developed as novel antimalarial and antibacterial agents.
description: EXCLI Journal;Vol. 15, 2016
Brownian Dynamics, Time-averaging and Colored Noise
Creators: name: Soares-Pinto, D. O.
name: Morgado, W. A. M.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: We propose a method to obtain the equilibrium distribution for positions and velocities of a one-dimensional particle via time-averaging and Laplace transformations. We apply it to the case of a damped harmonic oscillator in contact with a thermal bath. The present method allows us to treat, among other cases, a Gaussian noise function exponentially correlated in time, e.g., Gaussian colored noise. We obtain the exact equilibrium solution and study some of its properties.
description: 1 figure
Structure Formation Limits on Axion-Like Dark Matter
Creators: name: Baumholzer, Sven
name: Brdar, Vedran
name: Morgante, Enrico
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We derive structure formation limits on dark matter (DM) composed of keV-scale axion-like particles (ALPs), produced via freeze-in through the interactions with photons and Standard Model (SM) fermions. We employ Lyman-alpha (Ly-α) forest data sets as well as the observed number of Milky Way (MW) subhalos. We compare results obtained using Maxwell-Boltzmann and quantum statistics for describing the SM bath. It should be emphasized that the presence of logarithmic divergences complicates the calculation of the production rate, which can not be parameterized with a simple power law behaviour. The obtained results, in combination with X-ray bounds, exclude the possibility for a photophilic "frozen-in" ALP DM with mass below $\sim 19\,\mathrm{keV}$. For the photophobic ALP scenario, in which DM couples primarily to SM fermions, the ALP DM distribution function is peaked at somewhat lower momentum and hence for such realization we find weaker limits on DM mass. Future facilities, such as the upcoming Vera C. Rubin observatory, will provide measurements with which the current bounds can be significantly improved to $\sim 80\,\mathrm{keV}$.
description: 18 pages, 5 figures, minor updates in the discussion, main results unaltered
title: Ομαδοσυνεργατική διδασκαλία στα γενικά (ΓΕΛ) και επαγγελματικά (ΕΠΑΛ) λύκεια
title: Collaborative teaching in general (GEL) and vocational (EPAL) hiigh schools
titleType: AlternativeTitle
Creators: name: Σταθοπούλου, Στυλιανή
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ομαδοσυνεργατική διδασκαλία
subject: Δευτεροβάθμια εκπαίδευση
subject: Γενικά λύκεια (ΓΕΛ)
subject: Επαγγελματικά λύκεια (ΕΠΑΛ)

description: Η παρούσα μελέτη στοχεύει στη διερεύνηση, με βάση τις απόψεις των εκπαιδευτικών, της ομαδοσυνεργατικής διδασκαλίας στα γενικά και επαγγελματικά λύκεια. Στόχος της διπλωματικής αυτής εργασίας είναι να αναλυθεί η περίπτωση της ομαδοσυνεργατικής διδασκαλίας στην ελληνική εκπαίδευση, τα πλεονεκτήματα και τα μειονεκτήματα αυτής και πως αυτά επιβεβαιώνονται από την εμπειρία στην τάξη των εκπαιδευτικών στην Ελλάδα. Σκοπός είναι να προκύψουν συμπεράσματα αναφορικά με την ανάγκη περαιτέρω προώθησης της ομαδοσυνεργατικής διδασκαλίας στο ελληνικό εκπαιδευτικό σύστημα, καθώς και αναφορικά με τη μορφή που πρέπει να έχει. Πιο συγκεκριμένα, η διπλωματική εργασία αποτελείται από το θεωρητικό μέρος, στο οποίο αναλύεται ο ορισμός της ομαδοσυνεργατικής διδασκαλίας, οι βασικές αρχές που διέπουν την εν λόγω έννοια, καθώς και οι προϋποθέσεις για την αποτελεσματική εφαρμογή και προώθησή της στην εκπαίδευση. Επιπλέον, πραγματοποιείται μια ιστορική αναδρομή αναφορικά με τη «γέννηση» και εξέλιξη της ομαδοσυνεργατικής διδασκαλίας, κάνοντας ειδική αναφορά στις θεωρητικές προσεγγίσεις και τους ευρύτερους κοινωνικούς, οικονομικούς και άλλους λόγους που οδήγησαν στην εξέλιξη αυτής της μορφής διδασκαλίας. Περιγράφονται επίσης, τα πλεονεκτήματα και μειονεκτήματα της ομαδοσυνεργατικής διδασκαλίας για τους μαθητές, τους δασκάλους-εκπαιδευτικούς, το εκπαιδευτικό σύστημα και την κοινωνία γενικότερα. Όσον αφορά το πρακτικό μέρος, αρχικά αναλύεται η μεθοδολογία της έρευνας, εξηγώντας και αιτιολογώντας την επιλογή της κάθε μεθόδου. Έπειτα, παρουσιάζονται τα αποτελέσματα της πρωτογενούς έρευνας που πραγματοποιήθηκε και αναλύονται τα ερευνητικά ευρήματα. Τέλος, συνοψίζονται τα κύρια ευρήματα της έρευνας, εξάγονται τα κύρια συμπεράσματα που προκύπτουν από αυτά και προτείνονται ιδέες και κατευθύνσεις για μελλοντική έρευνα.
Black-Box Frontiers and Implications for Development Policy - Theoretical Considerations
Creators: name: Sauer, Johannes
name: Frohberg, Klaus
name: Hockmann, Heinrich
name: Sauer, Johannes
name: Frohberg, Klaus
name: Hockmann, Heinrich
Publisher: name: Unknown
Year: 2004
Subjects: International Development
Research and Development/Tech Change/Emerging Technologies

description: The availability of efficiency estimation software - freely distributed via the internet and relatively easy to use - recently inflated the number of corresponding applications. The resulting efficiency estimates are used without a critical assessment with respect to the literature on theoretical consistency, flexibility and the choice of the appropriate functional form. The robustness of policy suggestions based on inferences from efficiency measures nevertheless crucially depends on theoretically well-founded estimates. This paper addresses stochastic efficiency measurement by critically reviewing the theoretical consistency of recently published technical efficiency estimates with respect to economic development. The results confirm the need for a posteriori checking the regularity of the estimated frontier by the researcher and, if necessary, the a priori imposition of the theoretical requirements.
Vanishing of 3-Loop Jacobi Diagrams of Odd Degree
Creators: name: Moskovich, Daniel
name: Ohtsuki, Tomotada
Publisher: name: arXiv
Year: 2005
Subjects: subject: Geometric Topology (math.GT)
subject: Combinatorics (math.CO)
subject: FOS: Mathematics
subject: 57M27, 05C10

description: We prove the vanishing of the space of 3-loop Jacobi diagrams of odd degree. This implies that no 3-loop finite-type invariant can distinguish between a knot and its inverse.
description: 13 pages. Section on the even degree case expanded. Various minor corrections
title: Η συμβολή της τεχνολογίας στην αντιμετώπιση των προκλήσεων της υγείας του 21ου αιώνα και ειδικότερα της πανδημίας Covid-19
title: The contribution of ICT tools to confront the 21st century health challenges, in particular the Covid-19 pandemic
titleType: AlternativeTitle
Creators: name: Τσιάκκα, Βασιλική
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Ψηφιακή υγεία
subject: Cloud
subject: Δεδομένα
subject: Ηλεκτρονική υγεία
subject: Κινητή υγεία
subject: Προκλήσεις
subject: Πανδημία
subject: COVID-19
subject: Καραντίνα
subject: Lockdown
subject: Τεχνολογίες Πληροφοριών και Επικοινωνίας (ΤΠΕ)
subject: Ανάλυση SWOT
subject: e-Health
subject: m-Health

description: Σε καμία προηγούμενη χρονική περίοδο ο ιατρικός τομέας δεν κατείχε τόσο ποικίλα γνωστικά εργαλεία και τεχνολογικά μέσα. Ο χώρος της υγείας εδώ και αρκετά χρόνια αποτελεί πεδίο έρευνας και εφαρμογής νέων τεχνολογικών επιτευγμάτων. Η ανάγκη για τη δημιουργία ενός λειτουργικού, ευέλικτου και αποτελεσματικού συστήματος υγείας, ικανού να υπηρετεί τις ανάγκες των πολιτών χωρίς υψηλές δαπάνες αποτέλεσε την κινητήριο δύναμη για την επιβολή αλλαγών. Κύριοι στόχοι αυτής της διπλωματικής είναι η ανάδειξη, της εξαιρετικής σημασίας των ψηφιακών λύσεων και πιο συγκεκριμένα των εφαρμογών υγείας και των σύγχρονων προκλήσεων υγείας, οι οποίες πιέζουν τη βιωσιμότητα του συστήματος υγείας και επιβαρύνουν την υγεία των πολιτών Οι εφαρμογές της κινητής υγείας αναπτύσσονται ραγδαία με τη βοήθεια του κινητού τηλέφωνου με τα πεδία εφαρμογής της ηλεκτρονικής υγείας να έχουν πλέον εδραιωθεί. Μέσω της ανταλλαγής πληροφοριών και διασύνδεσης δεδομένων μεταξύ των πολιτών και παρόχων υγείας, η εξατομικευμένη φροντίδα υγείας, η έγκαιρη διάγνωση και η διαχείριση χρόνιων παθήσεων είναι γεγονός. Επίσης, ενισχύεται η πρόληψη, η υιοθέτηση ενός υγιούς τρόπου ζωής και η συμμόρφωση στη θεραπεία (mAdherence). Η πραγματικότητα όμως του 21ου αιώνα επιτάσσει τα εργαλεία των Τεχνολογιών Πληροφοριών και Επικοινωνιών (ΤΠΕ) και για την επιτήρηση και παρακολούθηση της δημόσιας υγείας. Συγκεκριμένα, η πανδημία Covid-19, οδήγησε όλη την ανθρωπότητα σε κατάσταση έκτακτης ανάγκης λόγω μη ύπαρξης εμβολίου και θεραπείας, με αποτέλεσμα τη ραγδαία και ανεξέλεγκτη εξάπλωση του ιού. Για αυτό το λόγο επιστρατεύτηκε η τεχνολογία, ώστε να καλύψει αυτό το κενό. Η βιβλιογραφική διπλωματική εργασία, δομήθηκε σε έξι κεφάλαια. Στο πρώτο κεφάλαιο παρουσιάζεται η ηλεκτρονική υγεία και οι έννοιες που την περιβάλλουν, στο δεύτερο κεφάλαιο παρουσιάζονται τα προγράμματα κινητής υγείας με βάση τον ΠΟΥ και εξετάζεται ο βαθμός υιοθέτησης τους από τα κράτη-μέλη. Στο τρίτο κεφάλαιο αναλύονται οι εφαρμογές της κινητής υγείας. Στο τέταρτο κεφάλαιο, παρουσιάζονται οι προκλήσεις υγείας του 21ου αιώνα και στο πέμπτο μελετάται ως περίπτωση η πανδημία του Covid-19 σε συνδυασμό με τα εργαλεία των ΤΠΕ. Τέλος, παρατίθενται τα συμπεράσματα.
The Final Agenda 2000 Agreement on Agriculture: An Assessment
Creators: name: Knaster, Beatriz
name: Knaster, Beatriz
Publisher: name: Unknown
Year: 1999
Subjects: Agricultural and Food Policy

description: This paper presents a general overview on the final Agenda 2000 Agreement on Agriculture, reached by the EU Heads of State in March 1999. Following a summary of the reforms agreed, the paper aims at assessing to which extent this package will suffice to address the two major external challenges facing the CAP: 1. Compliance with its current trade commitments at the World Trade Organisation and response to future pressures resulting from the new negotiating round starting at the end of 1999, and 2. Securing a smooth integration of the agricultural sectors of Central and Eastern European countries, which could start to accede the EU as early as 2002. The paper concludes that the agreement appears insufficient to address both challenges. The EU will have to adopt a very defensive position in WTO, being unable to pursue more offensive objectives such as the opening of foreign markets for its products. Moreover, key issues regarding EU enlargement, namely direct payments and supply controls, remain unresolved. Dieser Beitrag gibt einen Uberblick zu dem Agrarteil der Agenda 2000 entsprechend der Einigung der EU Regierungschefs im Marz 1999. Im Anschluss an eine Zusammenfassung der beschlossenen Reform findet eine Bewertung des Paketes im Hinblick auf die zwei wesentlichen Herausforderungen fur die GAP statt: 1. Berucksichtigung der gegenwartigen Handelsvereinbarungen im Rahmen der Welthandelsorganisation und der Vorbereitung der Ende des Jahres 1999 anstehenden neuen Verhandlungsrunde. 2. Vorbereitung einer moglichst problemlosen Integration der Agrarsektoren der Mittel- und Osteuropaischen Lander, die der EU bereits im Jahr 2002 beitreten konnten. Die Vereinbarungen der Agenda 2000 erscheinen ungenugend im Hinblick auf diese beiden Herausforderungen. Die EU ist gezwungen eine sehr defensive Position im Rahmen der WTO Verhandlungen einzunehmen. Eine klare Strategie zur Offnung der Weltmarkte fur eigene Produkte kann nicht verfolgt werden. Daruber hinaus bleiben die zentralen Probleme hinsichtlich der EU-Erweiterung, namlich Direktzahlungen und angebotsbeschränkende Instrumente, ungelost.
Spectrum of Trace Deformed Yang-Mills Theories
Creators: name: Athenodorou, Andreas
name: Cardinali, Marco
name: D'Elia, Massimo
Publisher: name: arXiv
Year: 2020
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper we study, by means of numerical simulations, the behaviour of the scalar glueball mass and the ground state of the torelon for trace deformed Yang-Mills theory defined on $ \mathbb{R}^3\times S^1$, in which center symmetry is recovered even at small compactification radii. We find, by investigating both $SU(3)$ and $SU(4)$ pure gauge theories, that the glueball mass computed in the deformed theory, when center symmetry is recovered, is compatible with its value at zero temperature and does not show any significant dependence on the compactification radius; moreover, we establish a connection between the deformation parameter and an effective compactification size, which works well at least for small deformations. In addition, we observe that the ground state of the torelon which winds around the small traced deformed circle with size $l$ acquires a pleateau for large values of the strength $h$, with values which are compatible with a $1/l$ behavior but, on the other hand, are still not in complete agreement with the asymptotic semiclassical large-$N$ predictions.
description: 12 pages, 11 figures. In v2, in addition to SU(3) we also provide results for SU(4) at one lattice spacing. Furthermore, we provide a connection between the deformation parameter h and an effective compactification size l_eff. Major revision to the text
Efficacy of Elaeagnus angustifolia extract in the treatment of knee osteoarthritis: a randomized controlled trial
Creators: name: Panahi, Yunes
name: Alishiri, Gholam Hossein
name: Bayat, Noushin
name: Hosseini, Seyed Morteza
name: Sahebkar, Amirhossein
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: osteoarthritis
subject: Elaeagnus angustifolia
subject: pain
subject: NSAID
subject: clinical trial
subject: 610

description: Osteoarthritis (OA) is one of the most common musculoskeletal disorders all over the world. Available antiarthritic medications have only partial efficacy and their long-term use is associated with adverse events. Elaeagnus Angustifolia (EA) is a medicinal plant with analgesic and anti-inflammatory properties. The present study evaluated the impact of two doses of EA extract compared with ibuprofen on the severity of disease in patients with knee OA. This study was designed as a randomized, double blind, active-controlled and parallel group trial. Patients with OA were randomized to receive 300 mg/day (n=33) or 600 mg/day (n=32) of EA aqueous extract, or 800 mg/day ibuprofen (n=32) for 7 weeks. EA extract contained 0.21 % (w/w) kaempferol according to HPLC. Efficacy of treatment was assessed using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Visual Analogue Scale (VAS) of pain, Lequesne’s Pain-Function Index (LPFI), and patient’s global assessment (PGA) index. The amount of kaempferol in the extract was determined by HPLC method to be 0.21 % w/w. There were significant reductions in WOMAC, VAS, LPFI and PGA scores by the end of trial with all three interventions. Comparison of the changes in WOMAC, VAS and LPFI scores among the treatment groups did not reveal any significant difference between EA and ibuprofen, and between low and high doses of EA. EA was safe and well tolerated during the course of trial and no adverse event was reported. The present results suggest beneficial effects of aqueous EA extract in reducing the symptoms of OA with an efficacy comparable to that of ibuprofen.
description: EXCLI Journal;Vol. 15, 2016
Channeling of high-energy particles in a multi-wall nanotube
Creators: name: Bellucci, S.
name: Biryukov, V. M.
name: Cordelli, A.
Publisher: name: arXiv
Year: 2005
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: Channeling of high-energy particles in straight and bent multi-wall nanotubes (MWNT) has been studied in computer simulations and compared to the channeling properties of single-wall nanotubes (SWNT) and bent crystal lattices. It is demonstrated that MWNT can efficiently channel positively-charged high-energy particles trapped between the walls of MWNT. Bending dechanneling in MWNT has been computed as a function of the particle momentum to nanotube curvature radius ratio, $pv/R$. It is found that a bent MWNT can steer a particle beam with bending capabilities similar to those of bent silicon crystal lattice and to those of best (i.e. the narrowest) SWNT. In view of channeling applications at particle accelerators, MWNT appear favored as compared to SWNT, because MWNT can be produced quite straight (and in aligned array), while SWNT is typically very curved, thus posing a severe problem for channeling applications. Therefore, we suggest that MWNT provide a better candidate for channeling than SWNT.
description: 16 pages, 6 figures, to appear in Phys. Lett. B
Ανάπτυξη των γνωστικών περιοχών της διοίκησης έργου και εφαρμογή τους στην κατασκευή βιοκλιματικής κατοικίας
Creators: name: Κίτσος, Χαράλαμπος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Διοίκηση έργου
subject: Κύκλος ζωής έργου
subject: Συμμέτοχοι
subject: Δραστηριότητες
subject: Έργο
subject: Παραδοτέα
subject: WBS
subject: Πόροι
subject: Κρίσιμη διαδρομή
subject: Βιοκλιματικά κτίρια

description: Στη παρούσα διπλωματική εργασία αρχικά παρουσιάζονται βασικές έννοιες που σχετίζονται με τη Διοίκηση Έργου και τη χρήση της στα κατασκευαστικά έργα. Στη συνέχεια, αναλύονται οι γνωστικές περιοχές της Διοίκησης Έργου σε συνδυασμό με τη παρουσίαση των εργαλείων και των τεχνικών που μπορούν να εφαρμοστούν σε κάθε περιοχή ξεχωριστά. Επίσης, παρουσιάζονται τα κατασκευαστικά στάδια, οι φάσεις ενός κατασκευαστικού έργου, επισημαίνονται τα κατασκευαστικά στάδια μιας βιοκλιματικής κατοικίας και τα πλεονεκτήματα που προσφέρουν έναντι των συμβατικών κατοικιών. Ακόμα, αναφέρονται λογισμικά διοίκησης έργων που είναι εξειδικευμένα για τα κατασκευαστικά έργα και ποια είναι τα χαρακτηριστικά που επιθυμούν να έχουν οι χρήστες τους. Επιπροσθέτως, παρουσιάζεται μία μελέτη περίπτωσης κατά την οποία παρουσιάζεται η εφαρμογή των γνωστικών περιοχών της Διοίκησης Έργου (στην κατασκευή μιας βιοκλιματικής κατοικίας στα Ιωάννινα). Συγκεκριμένα, εντοπίστηκαν οι συμμέτοχοι για τη κατασκευή της βιοκλιματικής κατοικίας, έγινε ο προγραμματισμός του έργου δημιουργώντας το ημερολόγιο των εργασιών, ορίστηκαν οι δραστηριότητες και η χρονική τους διάρκεια και δεσμεύτηκαν οι πόροι που απαιτούνταν για τη πραγματοποίηση της κάθε δραστηριότητας. Στη συνέχεια, έγινε ο εντοπισμός των πιθανών κινδύνων και η παρακολούθηση τους. Τέλος, πραγματοποιήθηκε η παρακολούθηση και ο έλεγχος του έργου από την σκοπιά του κόστους και του χρόνου ολοκλήρωσής του και παρουσιάστηκαν τα συμπεράσματα που προέκυψαν από την εκπόνηση της παρούσας διπλωματικής εργασίας.
Logarithmic interaction under periodic boundary conditions: Closed form formulas for energy and forces
Creators: name: Tyagi, Sandeep
Publisher: name: arXiv
Year: 2005
Subjects: subject: Other Condensed Matter (cond-mat.other)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences

description: A method is given to obtain closed form formulas for the energy and forces for an aggregate of charges interacting via a logarithmic interaction under periodic boundary conditions. The work done here is a generalization of Glasser's results [M. L. Glasser, J. Math. Phys. 15, 188 (1974)] and is obtained with a different and simpler method than that by Stremler [M. A. Stremler, J. Math. Phys. 45, 3584 (2004)]. The simplicity of the formulas derived here makes them extremely convenient in a computer simulation.
Open-Access-Policy Deutsches Historisches Institut Paris
Creators: name: Deutsches Historisches Institut Paris
Publisher: name: Zenodo
Year: 2022
Subjects: Open Access

description: Das DHIP unterstützt den Open-Access-Gedanken und setzt diesen auf vielfältige Weise in Publikationen, Wissenschaftskommunikation und in Beratung und Förderung der Forschenden des Instituts um. Die hier veröffentlichte Policy vom 1.3.2022 beinhaltet die Maßnahmen und Förderinstrumente des DHIP im Bereich Open Access und dient als Orientierung für die Forschenden am DHIP.
Impaired glucose and lipid metabolism in ageing aryl hydrocarbon receptor deficient mice
Creators: name: Biljes, Daniel
name: Hammerschmidt-Kamper, Christiane
name: Kadow, Stephanie
name: Diel, Patrick
name: Weigt, Carmen
name: Burkart, Volker
name: Esser, Charlotte
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: AHR
subject: metabolic syndrome
subject: diet
subject: dyslipidemia
subject: senescence
subject: 610

description: Disturbed homeostasis of glucose and lipid metabolism are dominant features of the so-called metabolic syndrome (MetS) and can increase the risk for the development of type 2 diabetes (T2D), a severe metabolic disease. T2D prevalence increases with age. The aryl hydrocarbon receptor (AHR) is a sensor of small molecules including dietary components. AHR has been identified as potential regulator of glucose homeostasis and lipid metabolism. Epidemiologically, exposure to xenobiotic AHR ligands such as polycyclic aromatic hydrocarbons is linked to T2D. We assess here the potential role of the AHR in disturbances of glucose and lipid metabolism in young (age 2-5 months) and old (age > 1,5 years) AHR-deficient (AHR KO) mice. Fasted young wildtype (WT) and AHR-KO mice displayed similar blood glucose kinetics after challenge with intra-peritoneal glucose injection. However, old AHR-KO mice showed lower tolerance than WT to i.p. administered glucose, i.e. glucose levels rose higher and returned more slowly to normal levels. Old mice had overall higher insulin levels than young mice, and old AHR-KO had a somewhat disturbed insulin kinetic in the serum after glucose challenge. Surprisingly, young AHR-KO mice had significantly lower triglycerides, cholesterol, high density lipoprotein values than WT, i.e., a dyslipidemic profile. With ageing, AHR-KO and WT mice did not differ in these lipid levels, except for slightly reduced levels of triglycerides and cholesterol. In conclusion, our findings in AHR KO mice suggest that AHR expression is relevant for the maintenance of glucose and lipid homeostasis in old mice.
description: EXCLI Journal;Vol. 14, 2015
Quantum thermo-dynamical construction for driven open quantum systems
Creators: name: Dann, Roie
name: Kosloff, Ronnie
Publisher: name: arXiv
Year: 2020
Subjects: subject: Quantum Physics (quant-ph)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: Quantum dynamics of driven open systems should be compatible with both quantum mechanic and thermodynamic principles. By formulating the thermodynamic principles in terms of a set of postulates we obtain a thermodynamically consistent master equation. Following an axiomatic approach, we base the analysis on an autonomous description, incorporating the drive as a large transient control quantum system. In the appropriate physical limit, we derive the semi-classical description, where the control is incorporated as a time-dependent term in the system Hamiltonian. The transition to the semi-classical description reflects the conservation of global coherence and highlights the crucial role of coherence in the initial control state. We demonstrate the theory by analyzing a qubit controlled by a single bosonic mode in a coherent state.
Functional near-infrared spectroscopy: a continuous wave type based system for human frontal lobe studies
Creators: name: Venclove, Sigita
name: Daktariunas, Algis
name: Ruksenas, Osvaldas
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: functional near-infrared spectroscopy
subject: non-invasive
subject: hemodynamic response
subject: cortical activation
subject: prototype
subject: 610

description: Functional Near-Infrared Spectroscopy (fNIRS) is an optical non-invasive brain monitoring technology that registers changes in hemodynamic responses within the cortex of the human brain. Over the last decades fNIRS became a promising method in neurosciences: it is non-invasive, portable and can be used in long term studies. All these advantages make it suitable for educational purposes as well. This paper presents basic methodological concept of optical engineering principles and suitable applications of fNIRS. We represent a continuous wave (cw-fNIRS) system that could be used for frontal lobe studies in human adults or as demonstration equipment for physiological measurements. This system has been validated by comparing it with commercial device fNIR400 from Biopac. A comparison of geometry, data and statistical analyses suggests similar hemodynamic responses recorded by both devices. Our study suggests that this system can be used for further development and as a guideline for researchers to develop a specific tool for applications in human brain studies.
description: EXCLI Journal;Vol. 14, 2015
Eye-blinks in choice response tasks uncover hidden aspects of information processing
Creators: name: Wascher, Edmund
name: Heppner, Holger
name: Möckel, Tina
name: Kobald, Sven Oliver
name: Getzmann, Stephan
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: eye-blinks
subject: EOG
subject: cognitive control
subject: attention
subject: natural marker
subject: 610

description: Spontaneous eye-blinks occur much more often than it would be necessary to maintain the tear film on the eyes. Various factors like cognitive demand, task engagement, or fatigue are influencing spontaneous blink rate. During cognitive information processing there is evidence that blinks occur preferably at moments that can be assigned to input stream segmentation. We investigated blinking behavior in three different visual choice response experiments (Experiment 1: spatial Stimulus-Response correspondence, Experiment 2: Change Detection, Experiment 3: Continuous performance Test - AX version). Blinks during the experimental tasks were suppressed when new information was expected, as well as during cognitive processing until the response was executed. Blinks in go trials occurred within a short and relatively constant interval after manual responses. However, blinks were not a side effect of manual behavior, as they occurred in a similar manner in no-go trials in which no manual response was executed. In these trials, blinks were delayed when a prepared response had to be inhibited, compared to trials in which no response was intended. Additionally, time on task effects for no-go blinks mirrored those obtained in go trials. Thus, blinks seem to provide a reliable measure for cognitive processing beyond (or rather additional to) manual responses.
description: EXCLI Journal;Vol. 14, 2015
Ανάπτυξη και ενορχήστρωση υπηρεσιών πληροφοριακών συστημάτων με χρήση serverless αρχιτεκτονικών
Creators: name: Μπατζιόπουλος, Σπυρίδων
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2021
Subjects: subject: Openwhisk
subject: Kubernetes
subject: Docker
subject: Serverless
subject: Quarkus
subject: Arm cluster

description: Παρατηρείται την τελευταία δεκαετία η μεγάλη ανάπτυξη στην υλοποίηση υπηρεσιών πληροφοριακών συστημάτων από οργανισμούς στο πλαίσιο του ψηφιακού μετασχηματισμού. Η serverless αρχιτεκτονική παρατηρείται να κερδίζει συνεχώς έδαφος καθώς δημιουργεί πολλαπλές δυνατότητες κλιμάκωσης και επέκτασης σε εντός ενός συστήματος ενορχήστρωσης όπως το kubernetes. Με αυτό τον συνδυασμό τεχνολογιών προκύπτει μεγάλη μείωση του κόστους, αποτελεσματική διαχείριση των πόρων και μείωση των χρόνων ανάπτυξης των εφαρμογών. Συστήματα serverless αρχιτεκτονικών – FaaS- όπως το Openwhisk και το Quarkus, που εξετάζονται, προσδίδουν όλα τα παραπάνω χαρακτηριστικά ανεξαρτήτως γλώσσας προγραμματισμού και λειτουργικού συστήματος.
Das neue Gentechnikgesetz - ein Gentechnikverhinderungsgesetz?
Creators: name: Becker, Alexander
name: Holm-Muller, Karin
name: Becker, Alexander
name: Holm-Muller, Karin
Publisher: name: Unknown
Year: 2005
Subjects: subject: Agricultural and Food Policy
subject: Research and Development/Tech Change/Emerging Technologies
subject: act for genetic engineering
subject: liability
subject: coexistence
subject: market loss

description: In addition to existing juridical analyses of the new German act for genetic engineering, this article deals with an environmental economic assessment. It is examined what kind of external costs will arise by using/applying genetic engineering and how they will be allocated. Our focus is on the costs that explicitly evolve from the societal postulated coexistence of conventional/ organic farms and users of biotechnology. If the protection of the existing production is accepted, as postulated by politics, the new act internalizes the so called market losses relatively well. In this context, the design of precautionary duties that have to be still established by law is of utmost importance. To avoid the dangers of an excessive liability by the farmer, it is from an economic point of view a good alternative, if the producers of genetically modified crops take the responsibility for any litigation claims to farmers. Furthermore negotiations between neighbouring farms could be an option to keep the costs for damage prevention to a minimum. Erganzend zu den bereits vorliegenden juristischen Analysen des neuen deutschen Gentechnikgesetzes beschaftigt sich der vorliegende Artikel mit einer umweltokonomischen Beurteilung. Untersucht wird, welche externen Kosten bei der Nutzung der "Grunen Gentechnik" entstehen und wie sie auf die Beteiligten verteilt werden. Dabei liegt der Fokus auf den Kosten, die explizit fur die gesellschaftlich geforderte Koexistenz von konventionellen/ okologischen Betrieben und Nutzern der Gentechnik entstehen. Wird der politisch gesetzte estandsschutz fur die bestehenden Produktionssysteme akzeptiert, so zeigt sich, dass eine korrekte Internalisierung der so genannten Vermarktungsschaden relativ gut erreicht werden kann. In diesem Zusammenhang spielt jedoch die Ausgestaltung der Vorsorgepflichten, die noch in einer Rechtsverordnung zur Guten fachlichen Praxis festgeschrieben warden mussen, eine erhebliche Rolle. Um der Gefahr einer Ubermasshaftung durch Landwirte zu begegnen, ist aus okonomischer Sicht die Haftungsubernahme durch die Hersteller der gentechnisch veranderten Pflanzen eine gute Moglichkeit. Auch bieten sich Verhandlungslosungen zwischen benachbarten Landwirten an, um eine kostenminimale Vermeidung von Schaden zu erreichen. Schlusselworter : gentechnikgesetz, haftung, koexistenz, vermarktungsschaden
A systematic review of the cardiotoxicity of methadone
Creators: name: Alinejad, Samira
name: Kazemi, Toba
name: Zamani, Nasim
name: Hoffman, Robert S.
name: Mehrpour, Omid
Publisher: name: Technische Universität Dortmund
Year: 2015
Subjects: subject: Methadone
subject: toxicity
subject: heart
subject: ECG
subject: torsade de pointes
subject: QT interval
subject: 610

description: Methadone is one of the most popular synthetic opioids in the world with some favorable properties making it useful both in the treatment of moderate to severe pain and for opioid addiction. Increased use of methadone has resulted in an increased prevalence of its toxicity, one aspect of which is cardiotoxicity. In this paper, we review the effects of methadone on the heart as well as cardiac concerns in some special situations such as pregnancy and childhood. Methods: We searched for the terms methadone, toxicity, poisoning, cardiotoxicity, heart, dysrhythmia, arrhythmia, QT interval prolongation, torsade de pointes, and Electrocardiogram (ECG) in bibliographical databases including TUMS digital library, PubMed, Scopus, and Google Scholar. This review includes relevant articles published between 2000 and 2013. The main cardiac effects of methadone include prolongation of QT interval and torsade de pointes. Other effects include changes in QT dispersion, pathological U waves, Taku-Tsubo syndrome (stress cardiomyopathy), Brugada-like syndrome, and coronary artery diseases. The aim of this paper is to inform physicians and health care staff about these adverse effects. Effectiveness of methadone in the treatment of pain and addiction should be weighed against these adverse effects and physicians should consider the ways to lessen such undesirable effects. This article presents some recommendations to prevent heart toxicity in methadone users.
description: EXCLI Journal;Vol. 14, 2015
Οι αντιλήψεις των εκπαιδευτικών σχετικά με τη συμβολή των διευθυντικών στελεχών στην αποτελεσματική λειτουργία των σχολικών μονάδων της δευτεροβάθμιας εκπαίδευσης
Creators: name: Γεωργόπουλος, Αλέξανδρος
Publisher: name: Πανεπιστήμιο Πειραιώς
Year: 2020
Subjects: subject: Διευθυντικά στελέχη
subject: Δευτεροβάθμια εκπαίδευση
subject: Σχολικές μονάδες

description: Τα τελευταία 10 χρόνια έχει παρατηρηθεί μια δραματική ανάπτυξη της επιστημονικής έρευνας σε σχέση με την περιγραφή και την ανάλυση της έννοιας της εκπαιδευτικής ηγεσίας και της σχολικής διαχείρισης. Την ίδια στιγμή, οι δυνάμεις της τεχνολογίας της πληροφορίας, της παγκοσμιοποίησης, και της οικονομίας που βασίζεται πλέον στη γνώση, έχουν επιφέρει και έχουν οδηγήσει σε μια εποχή επιταχυνόμενων και καταλυτικών αλλαγών, σε επίπεδο κοινωνιών και σχολείων. Η εκπαιδευτική ηγεσία βρίσκεται στο επίκεντρο αυτών των δραματικών αλλαγών. Ο ΟΟΣΑ, έχει επισημάνει και εντοπίσει τις παγκόσμιες τάσεις σε ότι αφορά τα εκπαιδευτικά περιβάλλοντα/ πλαίσια των επόμενων χρόνων. Αυτές οι τάσεις αφορούν τη διαχείριση της αλλαγής στα σχολεία, την ανάπτυξη και υποστήριξη των σχολικών ηγετών, την επιτυχή προσαρμογή των εκπαιδευτικών σε νέα μοντέλα επαγγελματικής ανάπτυξης, την εξατομικευμένη και συνδυασμένη μάθηση, την αξιοποίηση των πόρων και την οικοδόμηση σχέσεων με την κοινότητα. Οι εκπαιδευτικοί ηγέτες αντιμετωπίζουν πρωτοφανείς πιέσεις σε ένα κλάδο όπου η αξιολόγηση διενεργείται βάση των αποτελεσμάτων. Καθώς αυτές οι περιβαλλοντικές πιέσεις εντείνονται, οι ηγέτες και οι σχολικοί διευθυντές απαιτείται να διαθέτουν περισσότερη κατανόηση, ανεπτυγμένες δεξιότητες και ανθεκτικότητα.
Physical parameters of the O6.5V+B1V eclipsing binary system LS 1135
Creators: name: Lajus, E. Fernandez
name: Niemela;, V. S.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: ASAS photometric observations of LS 1135, an O-type SB1 binary system with an orbital period of 2.7 days, show that the system is also eclipsing. This prompted us to re-examine the spectra used in the previously published spectroscopic orbit. Our new analysis of the spectra obtained near quadratures, reveal the presence of faint lines of the secondary component. We present for the first time a double-lined radial velocity orbit and values of physical parameters of this binary system. These values were obtained by analyzing ASAS photometry jointly with the radial velocities of both components performing a numerical model of this binary based on the Wilson-Devinney method. We obtained an orbital inclination i ~ 68.5 deg. With this value of the inclination we deduced masses M1 ~ 30 +/- 1 Mo and M2 ~ 9 +/- 1 Mo; and radii R1 ~ 12 +/- 1 Ro and R2 ~ 5 +/- 1 Ro for primary and secondary components, respectively. Both components are well inside their respective Roche lobes. Fixing the Teff of the primary to the value corresponding to its spectral type (O6.5V), the Teff obtained for the secondary component corresponds approximately to a spectral type of B1V. The mass ratio M2/M1 ~ 0.3 is among the lowest known values for spectroscopic binaries with O-type components.
description: 5 pages, 4 figures, 3 tables. Accepted for publication in MNRAS. The definitive version will be available at www.blackwell-synergy.com
Genetic factors associated with disease severity in rheumatoid arthritis
Creators: name: Khani-Hanjani, Abbas
Publisher: name: University of British Columbia
Year: 2009

description: Rheumatoid arthritis (RA) is a chronic, debilitating disease characterized by inflammatory thickening of articular soft tissue, with extension of the synovium over the articular cartilage, cartilaginous destruction and subchondral erosion leading to progressive joint deformity and immobility. RA currently affects over half a million subjects in Canada. More than 1,300 patients die annually from gastric bleeding secondary to the use of NSAIDs. The clinical manifestations of RA encompass a spectrum ranging from mild to severe disease, with irreversible joint damage and disability. Our current understanding does not allow for the accurate prediction of the severity in RA. Yet, increasing evidence suggests that early intervention with immunosuppressive drugs may mitigate the relentless progression of this disease and prevent irreversible joint damage. The main objective of this study was to explore selected immune response genes potentially involved in disease severity using patient populations stratified according to disease severity. PCR-RFLP and fragment length analyses of microsatellites were used to study the effect of genetic polymorphisms of nine genes on chromosomes 2, 4, 6, 12 and 22, which included HLA-DRβ1, HLA-DQβ1, HLA-DPβ1, TNF, IL-1β, IL-IRN, IL-2, IL-2Rβ, and IFNγ. HLA-DRβ1 alleles containing the QKRAA or QRRAA epitope, HLA-DQβ1*302, HLA-DPβ1 *401 and the 126bp allele of IFNγ were identified as high risk alleles, which demonstrate a significant association with the severe RA. In contrast the HLA-DRβ1 alleles containing the DERRA epitope and HLDRβ1*8, HLA-DQβ 1*402/502/603/604, HLA-DPβ1*201/501/1001 and the 122bp allele of IFNγ were significantly decreased in frequency in the population with severe RA compared to those with mild disease, suggesting a potential protective effect of these alleles on the progression of the disease. The distribution of genetic polymorphism for all other gene markers were either similar between populations or had a statistically insignificant value in the prediction of the severity of RA. The combination of HLA class II and IFNγ high-risk alleles yielded a more specific prediction of disease severity. A logistic regression model was designed which incorporated demographic and clinical data, HLA class II and IFNγ gene polymorphisms in order to predict the severity of disease. The model was able to discriminate between mild and severe RA patients with an odds ratio of greater than 447, Chi-square=28.83, p<0.0001 and an overall accuracy of over 90%.
Chiral high-harmonic generation and spectroscopy on solid surfaces using polarization-tailored strong fields
Creators: name: Heinrich, Tobias
name: Taucer, Marco
name: Kfir, Ofer
name: Corkum, P. B.
name: Staudte, André
name: Ropers, Claus
name: Sivis, Murat
Publisher: name: arXiv
Year: 2020
Subjects: subject: Optics (physics.optics)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Strong-field methods in solids enable new strategies for ultrafast nonlinear spectroscopy and provide all-optical insights into the electronic properties of condensed matter in reciprocal and real space. Additionally, solid-state media offers unprecedented possibilities to control high-harmonic generation using modified targets or tailored excitation fields. Here we merge these important points and demonstrate circularly-polarized high-harmonic generation with polarization-matched excitation fields for spectroscopy of chiral electronic properties at surfaces. The sensitivity of our approach is demonstrated for structural helicity and termination-mediated ferromagnetic order at the surface of silicon-dioxide and magnesium oxide, respectively. Circularly polarized radiation emanating from a solid sample now allows to add basic symmetry properties as chirality to the arsenal of strong-field spectroscopy in solids. Together with its inherent temporal (femtosecond) resolution and non-resonant broadband spectrum, the polarization control of high harmonics from condensed matter can illuminate ultrafast and strong field dynamics of surfaces, buried layers or thin films.
description: 24 pages, 5 figures
Connexins and pannexins in liver damage
Creators: name: Crespo Yanguas, Sara
name: Willebrords, Joost
name: Maes, Michaël
name: Da Silva, Tereza Cristina
name: Veloso Alves Pereira, Isabel
name: Cogliati, Bruno
name: Zaidan Dagli, Maria Lucia
name: Vinken, Mathieu
Publisher: name: Technische Universität Dortmund
Year: 2016
Subjects: subject: connexin
subject: pannexin
subject: acute liver injury
subject: steatosis
subject: hepatitis
subject: cholestasis
subject: fibrosis
subject: liver cancer
subject: 610

description: Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these deleterious events connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets.
description: EXCLI Journal;Vol. 15, 2016