cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Putting Contingency Management Research into Practice: A Canadian Randomized Effectiveness Trial of Contingency Management for Treatment Attendance
Creators: name: Cowie, Megan
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: contingency management
subject: substance use disorder treatment
subject: effectiveness trial
subject: Psychology--Clinical
subject: Psychology--Behavioral

description: Introduction: Contingency management (CM) is an effective evidence-based treatment (EBT) used as an adjunct to usual care for individuals with substance use disorders (SUDs). However, its use in clinical practice is limited, particularly in Canada. This study implemented and evaluated the effectiveness of CM for SUDs in two outpatient addiction clinics in Alberta. Methods: We recruited and randomized 93 participants for a three-month, two-armed, parallel-group, unblinded intervention which compared attendance-based CM (n=47) to a treatment-as-usual (TAU) control group (n=46). In total, five participants were later excluded due to ineligibility. Therefore, in total, 88 participants were analyzed: 43 participants in CM, 45 in TAU. Participants in the CM group were incentivized using a hybrid prize-and voucher method. Specifically, attendance at treatment was rewarded with draws from a virtual prize bowl which accrued incrementally based on consecutive attendance. Our outcomes related to differences in treatment retention, attendance, substance use, and quality of life between CM and TAU. Results: Participants in CM were less likely to drop out of treatment, were retained in treatment for longer durations, attended more treatment sessions, and attended treatment more consistently compared to participants in TAU. No other differences between groups were observed for substance use outcomes or quality of life. Conclusion: Our results support the adaptability of CM in the Canadian context to improve treatment retention and attendance. The remote capabilities of CM reduce the barriers for accessing this EBT, allowing for greater reach of this intervention. The results highlight how CM can be tailored to be more economical through its focus on attendance, a focus consistent with the growing movement towards a harm-reduction approach to addiction recovery in Canada.
Riding the Waves of Flux: Newcomer Narratives on Their Lived Experiences Inside and Out of the Language Instruction for Newcomers to Canada (LINC) Program
Creators: name: Vergara, Oscar Michael
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Language Instruction for Newcomers to Canada (LINC)
subject: Newcomer Narratives
subject: Portfolio Based Language Assessment (PBLA)
subject: Narrative Inquiry
subject: Multiculturalism
subject: Education--Adult and Continuing

description: Abstract This research was aimed at studying the stories of nine former newcomers in the Language Instruction for Newcomers to Canada (LINC) program which is offered across Canada. The study of multiple individual stories is naturally qualitative in scope. It set out to explore nine individual stories and to learn from the perceptions of former newcomers previously in the LINC program and its effects/influences on their lives inside and out of language instruction classes. The study employed Narrative Inquiry to ensure a holistic picture of each individual’s life’s story was included as part of the data. The sources of data include (a) focus groups sessions, (b) semi-structured interviews, and (c) manual coding with reflective notes. The findings indicated several influences on the nine individuals of coming to Canada including the overall satisfaction with LINC, and its effect on their future pathways. In addition, this study’s newcomer-participants point to a variety of feedback that could be applied to future LINC participants’ learning and general programming. The various stakeholders, including policy makers, administrators, practitioners, and researchers, that work with LINC programs, may find the findings and recommendations particularly useful in extending and expanding on the flexibility that existing LINC programming already offers. Keywords: LINC, PBLA, multiculturalism, newcomers, narratives, flux
Chronic Disease After Natural Disasters: Public Health, Policy, and Provider Perspectives
Creators: name: Suneja, Amit
name: Chandler, Thomas E.
name: Schlegelmilch, Jeffrey
name: May, Michael
name: Redlener, Irwin E.
Publisher: name: Columbia University
Year: 2018
Subjects: Emergency management
Emergency management--Planning
Natural disasters
Natural disasters--Management
Natural disasters--Planning
Chronically ill

description: Individuals with chronic conditions require special attention in the planning, response, and recovery phases of disasters, given their unique needs for medication, medical equipment, continued medical care, and the potential for exacerbation of their conditions that require resource-intensive management.

In addition to exacerbating existing disease, disasters also contribute to the development of new chronic illnesses. The estimated cumulative cost of natural disasters in 2017 was over $300 billion. With the expected increase in severity of natural disasters in the setting of climate change, understanding the post-disaster burden of these diseases and the approach by local, state, and federal agencies in preparing for and responding to them in disaster settings is as important as ever.

Over 60% of Americans have at least one chronic condition, and over 40% have multiple. Decades of research have characterized the post-disaster burden of chronic conditions, and authors have more recently begun to discuss how a more unified approach can be taken by public health practitioners and public officials in the disaster sphere to better address the needs of this population across the disaster lifecycle.

The purpose of this report is to provide public and private stakeholders, especially at the state and local levels, with a resource to help them better understand, and support, the needs of this subgroup. We achieve this by providing a review of key research addressing the burden of chronic diseases, their management, and broader solutions across the disaster life cycle followed by 15 interviews conducted with direct service providers, as well as public health and policy leaders working at the local, state, and federal level. Our interviews highlight the strengths and weaknesses that have been experienced or are anticipated in current approaches to this issue and provide direction for next steps in research, policy, and public health practice as more Americans develop chronic conditions.
Loschmidt echo with a non-equilibrium initial state: early time scaling and enhanced decoherence
Creators: name: Mukherjee, Victor
name: Sharma, Shraddha
name: Dutta, Amit
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We study the Loschmidt echo (LE) in a central spin model in which a central spin is globally coupled to an environment (E) which is subjected to a small and sudden quench at $t=0$ so that its state at $t=0^+$, remains the same as the ground state of the initial environmental Hamiltonian before the quench; this leads to a non-equilibrium situation. This state now evolves with two Hamiltonians, the final Hamiltonian following the quench and its modified version which incorporates an additional term arising due to the coupling of the central spin to the environment. Using a generic short-time scaling of the decay rate, we establish that in the early time limit, the rate of decay of the LE (or the overlap between two states generated from the initial state evolving through two channels) close to the quantum critical point (QCP) of E is independent of the quenching. We do also study the temporal evolution of the LE and establish the presence of a crossover to a situation where the quenching becomes irrelevant. In the limit of large quench amplitude the non-equilibrium initial condition is found to result in a drastic increase in decoherence at large times, even far away from a QCP. These generic results are verified analytically as well as numerically, choosing E to be a transverse Ising chain where the transverse field is suddenly quenched.
description: 5 pages, 6 figures; New results, figures and references added, title changed
Parmotrema mellissii Hale
Creators: name: R, Jeanne dos
name: Silva, eis
name: Aptroot, André
name: E, Marcela
name: S, ugenia da
name: Cáceres, ilva
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Lecanoromycetes
Lecanorales
Parmeliaceae
Parmotrema
Parmotrema mellissii

description: Parmotrema mellissii (C.W.Dodge) Hale
PREVIOUS REPORT. — Mistry (1998).
description: Published as part of R, Jeanne dos, Silva, eis, Aptroot, André, E, Marcela, S, ugenia da & Cáceres, ilva, 2023, Lichens from dry central Brazil: a checklist of lichenized fungi from Distríto Federal and Goiás, pp. 117-133 in Cryptogamie, Mycologie 20 (9) on page 122, DOI: 10.5252/cryptogamie-mycologie2023v44a9, http://zenodo.org/record/8434271
Compound Words and Close-Knit Phrases in Wik-Munkan
Creators: name: Kilham, Christine (Ed.)
Publisher: name: Pacific Linguistics
Year: 1974

description: COMPOUND WORDS AND CLOSE-KNIT PHRASES IN WIK-MUNKAN. 45 0. INTRODUCTION 45 1. ROLE OF BODY PARTS 45 2. SEMANTIC RELATIONSHIPS 52 3. CRITERIA FOR DIFFERENTIATING COMPOUND WORDS AND CLOSE-KNIT PHRASES 56 4. CRITERIA APPLIED TO DATA 58NOTES 70BIBLIOGRAPHY 73
Tone-mapping high dynamic range images and videos for bit-depth scalable coding and 3D displaying
Creators: name: Mai, Zicong
Publisher: name: University of British Columbia
Year: 2012

description: High dynamic range (HDR) images and videos provide superior picture quality by allowing a larger range of brightness levels to be captured and reproduced than their traditional 8-bit low dynamic range (LDR) counterparts. Even with existing 8-bit displays, picture quality can be significantly improved if the content is first captured in HDR format and then converted to LDR format. This converting process is called tone-mapping. In this thesis, we address different aspects of tone-mapping. HDR video formats are unlikely to be broadly accepted without the backward-compatibility with LDR devices. We first consider the case where only the tone-mapped LDR content is transmitted and the HDR video is reconstructed at the receiver by inversely tone-mapping the encoded-decoded LDR video. We show that the appropriate choice of a tone-mapping operator can result in a reconstructed HDR video with good quality. We develop a statistical model of the distortion resulting from tone-mapping, compressing, de-compressing and inverse tone-mapping the HDR video. This model is used to formulate an optimization problem that finds the tone-curve that minimizes the distortion in the reconstructed HDR video. We also derive a simplified version of the model that leads to a closed-form solution for the optimization problem. Next, we consider the case where the HDR content is transmitted using an LDR and an enhancement layers. We formulate an optimization problem that minimizes the transmitted bit-rate of a video sequence and also results in the tone-mapped video that satisfies some desired perceptual appearance. The problem formulation also contains a constraint that suppresses temporal flickering artifacts. We also propose a technique that tone-maps an HDR video directly in a compression friendly color space (e.g., YCbCr) without the need to convert it to the RGB domain. We study the design of 3D HDR-LDR tone-mapping operators. To find the appropriate tone-mapping characteristics that contribute to good 3D representation, subjective psychophysical experiments are performed for i) evaluating existing tone-mapping operators on 3D HDR images and ii) investigating how the preferred level of brightness and details differ between 3D and 2D images. The results are analyzed to find out the desired attributes.
Character formulæ and GKRS multiplets in equivariant K-theory
Creators: name: Landweber, Gregory D.
name: Sjamaar, Reyer
Publisher: name: arXiv
Year: 2011
Subjects: subject: K-Theory and Homology (math.KT)
subject: Algebraic Topology (math.AT)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics

description: Let $G$ be a compact Lie group, $H$ a closed subgroup of maximal rank and $X$ a topological $G$-space. We obtain a variety of results concerning the structure of the $H$-equivariant K-ring $K_H^*(X)$ viewed as a module over the $G$-equivariant K-ring $K_G^*(X)$. One result is that the module has a nonsingular bilinear pairing; another is that the module contains multiplets which are analogous to the Gross-Kostant-Ramond-Sternberg multiplets of representation theory.
description: 42 pages
Using Hierarchical Growth Modeling to Promote District Systematic Improvement in Ohio and Texas
Creators: name: Bowers, Alex J.
name: Ni, Xinyu
name: Esswein, Jennifer
Publisher: name: Columbia University
Year: 2018
Subjects: School districts--Evaluation
Educational evaluation
Linear models (Statistics)
Multilevel models (Statistics)
Longitudinal studies

description: The purpose of this study is to apply hierarchical linear growth modelling to district demographic and effectiveness data in the U.S. states of Ohio and Texas to identify districts that are significantly outperforming or underperforming their demographic and resource characteristics from the entire population of districts in a state. The study focuses on administrative panel data for the years 2006-2012 for all districts in Ohio (n=608) and 2005-2011 for all districts in Texas (n=1028). Our findings indicate that: 1) Multiple district demographic variables and financial expenditures, such as enrollment, student ethnicity, district location, and general and school administration expenditures per pupil have a significant relationship to growth in district academic achievement; 2) we identified 32 significantly outperforming districts in Texas and 15 districts in Ohio; 3) we compare this identification system with state accountability indicators through a quadrant plot to provide a new framework for site selection in district effectiveness research, which has important implications for the policy and practice of re-envisioning school district effectiveness.
On thermodynamic modeling and the role of the second law of thermodynamics in geophysics
Creators: name: Wilmanski, Krzysztof
Publisher: name: Weierstrass Institute
Year: 2003
Subjects: subject: thermodynamics
subject: geophysics
subject: poroelastic materials
subject: 80-01
subject: 74A99
subject: 74F10

description: The article contains a brief review of elements of thermodynamic modeling in theoretical geophysics. We motivate the existence of the second law of thermodynamics in macroscopic theoretical physics and demonstrate its evaluation. In particular we show its consequences in the construction of constitutive laws for a two-component poroelastic medium. This construction is also related to microstructural properties verified by means of the second law.
title: One-Dimensional Turbulence Simulations for Reactive Flows in Open and Closed Systems
Creators: name: Starick, T.
name: J. A. Medina, M.
name: H. Schmidt
Publisher: name: Otto von Guericke University Library, Magdeburg, Germany
Year: 2019

description: Technische Mechanik; 39; 1; 162-174; ISSN 2199-9244
description: The One-Dimensional Turbulence (ODT) model is applied to reactive flows in open and closed systems representedby a lifted jet flame in a vitiated coflow, and a constant volume autoignition configuration, respectively. ODT is aone-dimensional model for turbulent flow simulations, which uses a stochastic formulation to represent the effectsof  turbulent  advection.   Diffusion  and  reaction  effects  along  the  ODT  domain  are  considered  by  deterministicevolution equations.This work is an effort to verify the applicability and efficiency of the model for open and closed systems.  In theopen system case, ODT results are compared against experimental results of a lifted methane/air jet flame detailedin the work of Cabra et al. (2005).   In the closed system case,  a periodic,  constant volume domain is used toinvestigate the sensitivity of the ignition evolution to initial temperature and composition inhomogeneities of alean n-heptane/air mixture.   In the latter context,  ODT results are compared to DNS results from Luong et al.(2015). The results for the jet and constant volume configuration show a reasonable match with the experimentaland DNS data, considering the reduced order of the model and the underlying assumptions for each case.  At thejet configuration, a dependence of the flame evolution on the turbulence intensity parameter can be seen.  For theclosed system, initial temperature and composition inhomogeneities allow a mitigation of the undesirable rapidpressure rise due to locally different ignition delay times.
Structure and evolution of circumbinary disks around supermassive black hole (SMBH) binaries
Creators: name: Rafikov, Roman R.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: It is generally believed that gaseous disks around supermassive black hole (SMBH) binaries in centers of galaxies can facilitate binary merger and give rise to observational signatures both in electromagnetic and gravitational wave domains. We explore general properties of circumbinary disks by reformulating standard equations for the viscous disk evolution in terms of the viscous angular momentum flux F_J. In steady state F_J is a linear function of the specific angular momentum, which is a generalization of (but is not equivalent to) the standard constant \dot M disk solution. If the torque produced by the central binary is effective at stopping gas inflow and opening a gap (or cavity) in the disk, then the inner part of the circumbinary disk can be approximated as a constant F_J disk. We compute properties of such disks in different physical regimes relevant for SMBH binaries and use these results to understand the gas-assisted evolution of SMBH pairs starting at separations 10^{-4}-10^{-2} pc. We find the following. (1) Pile-up of matter at the inner edge of the disk leads to continuous growth of the torque acting on the binary and can considerably accelerate its orbital evolution compared to the gravitational wave-driven decay. (2) Torque on the binary is determined non-locally and does not in general reflect the disk properties in the vicinity of the binary. (3) Binary evolution depends on the past history of the disk evolution. (4) Eddington limit can be important in circumbinary disks even if they accrete at sub-Eddington rates at late stages of binary evolution. (5) Circumbinary disk self-consistently evolved under the action of the binary torque emits more power and has spectrum different from the spectrum of constant \dot M disk - it is steeper (νF_ν\propto ν^{12/7}) and extends to shorter wavelength, facilitating its detection.
description: Discussion of overflow across the orbit of the secondary added in section 5.2.6. 23 pages, 10 figures, submitted to ApJ
title: ประวัติศาสตร์แห่งชนชั้นและความเหลื่อมล้ำทางภาษา-วัฒนธรรมชนชาติพื้นเมืองในสังคมลุ่มแม่น้ำโขงตอนล่าง
Creators: name: ธันวา ใจเที่ยง
Publisher: name: สาขารัฐประศาสนศาสตร์ คณะศิลปศาสตร์ มหาวิทยาลัยกาฬสินธุ์
publisherIdentifierScheme: ROR
Year: 2012
Subjects: การกดขี่ทางภาษาและชนชาติ
ชนชาติบรู
ชนชาติส่วนน้อย
Oppression in Language and Culture
Bru People
Minority Groups

description: วารสารรัฐศาสตร์และนิติศาสตร์ มหาวิทยาลัยราชภัฏกาฬสินธุ์, 1, 1, 126-145
Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES
Creators: name: Pisareva, Vera P.
name: Pisarev, Andrey V.
name: Fernández, Israel S.
Publisher: name: Columbia University
Year: 2018
Subjects: Virology
RNA
Hepatitis C virus
Biochemistry

description: Co-opting the cellular machinery for protein production is a compulsory requirement for viruses. The Cricket Paralysis Virus employs an Internal Ribosomal Entry Site (CrPV-IRES) to express its structural genes in the late stage of infection. Ribosome hijacking is achieved by a sophisticated use of molecular mimicry to tRNA and mRNA, employed to manipulate intrinsically dynamic components of the ribosome. Binding and translocation through the ribosome is required for this IRES to initiate translation. We report two structures, solved by single particle electron cryo-microscopy (cryoEM), of a double translocated CrPV-IRES with aminoacyl-tRNA in the peptidyl site (P site) of the ribosome. CrPV-IRES adopts a previously unseen conformation, mimicking the acceptor stem of a canonical E site tRNA. The structures suggest a mechanism for the positioning of the first aminoacyl-tRNA shared with the distantly related Hepatitis C Virus IRES.
Landau Damping in a Turbulent Setting
Creators: name: Plunk, G. G.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Space Physics (physics.space-ph)
subject: FOS: Physical sciences

description: To address the problem of Landau damping in kinetic turbulence, the forcing of the linearized Vlasov equation by a stationary random source is considered. It is found that the time-asymptotic density response is dominated by resonant particle interactions that are synchronized with the source. The energy consumption of this response is calculated, implying an effective damping rate, which is the main result of this paper. Evaluating several cases, it is found that the effective damping rate can differ from the Landau damping rate in magnitude and also, remarkably, in sign. A limit is demonstrated in which the density and current become phase-locked, which causes the effective damping to be negligible; this potentially resolves an energy paradox that arises in the application of critical balance to a kinetic turbulence cascade.
description: Introduction significantly expanded to help contextualize results. Calculations unchanged
Physcia atrostriata Moberg
Creators: name: R, Jeanne dos
name: Silva, eis
name: Aptroot, André
name: E, Marcela
name: S, ugenia da
name: Cáceres, ilva
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Lecanoromycetes
Caliciales
Physciaceae
Physcia
Physcia atrostriata

description: Physcia atrostriata Moberg
PREVIOUS REPORT. — Mistry (1998).
NEW REPORT. — Parque Nacional de Brasília, on bark, leg. J.A.R. Silva, ISE 53269.
description: Published as part of R, Jeanne dos, Silva, eis, Aptroot, André, E, Marcela, S, ugenia da & Cáceres, ilva, 2023, Lichens from dry central Brazil: a checklist of lichenized fungi from Distríto Federal and Goiás, pp. 117-133 in Cryptogamie, Mycologie 20 (9) on page 123, DOI: 10.5252/cryptogamie-mycologie2023v44a9, http://zenodo.org/record/8434271
From Scattering Amplitudes to the Dilatation Generator in N=4 SYM
Creators: name: Zwiebel, Benjamin I.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: The complete spin chain representation of the planar N=4 SYM dilatation generator has long been known at one loop, where it involves leading nearest-neighbor 2 -> 2 interactions. In this work we use superconformal symmetry to derive the unique solution for the leading L -> 2 interactions of the planar dilatation generator for arbitrarily large L. We then propose that these interactions are given by the scattering operator that has N=4 SYM tree-level scattering amplitudes as matrix elements. We provide compelling evidence for this proposal, including explicit checks for L=2,3 and a proof of consistency with superconformal symmetry.
description: 39 pages, v2: reference added and minor changes, published version
Routine single particle CryoEM sample and grid characterization by tomography
Creators: name: Noble, Alex J.
name: Dandey, Venkata P.
name: Wei, Hui
name: Brasch, Julia
name: Chase, Jillian
name: Acharya, Priyamvada
name: Tan, Yong Zi
name: Zhang, Zhening
name: Kim, Laura Y.
name: Scapin, Giovanna
name: Rapp, Micah Allen
name: Eng, Edward T.
name: Rice, William J.
name: Cheng, Anchi
name: Negro, Carl J.
name: Shapiro, Lawrence S.
name: Kwong, Peter D.
name: Jeruzalmi, David
name: Des Georges, Amedee
name: Potter, Clinton
name: Carragher, Bridget
Publisher: name: Columbia University
Year: 2018
Subjects: Tomography
Biochemistry
Particles
Biophysics
Electron microscopy

description: Single particle cryo-electron microscopy (cryoEM) is often performed under the assumption that particles are not adsorbed to the air-water interfaces and in thin, vitreous ice. In this study, we performed fiducial-less tomography on over 50 different cryoEM grid/sample preparations to determine the particle distribution within the ice and the overall geometry of the ice in grid holes. Surprisingly, by studying particles in holes in 3D from over 1000 tomograms, we have determined that the vast majority of particles (approximately 90%) are adsorbed to an air-water interface. The implications of this observation are wide-ranging, with potential ramifications regarding protein denaturation, conformational change, and preferred orientation. We also show that fiducial-less cryo-electron tomography on single particle grids may be used to determine ice thickness, optimal single particle collection areas and strategies, particle heterogeneity, and de novo models for template picking and single particle alignment.
Factorization of Heavy-to-Light Baryonic Transitions in SCET
Creators: name: Wang, Wei
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the framework of the soft-collinear effective theory, we demonstrate that the leading-power heavy-to-light baryonic form factors at large recoil obey the heavy quark and large energy symmetries. Symmetry breaking effects are suppressed by $Λ/m_{b}$ or $Λ/E$, where $Λ$ is the hadronic scale, $m_b$ is the $b$ quark mass and $E\sim m_b$ is the energy of light baryon in the final state. At leading order, the leading power baryonic form factor $ξ_{Λ,p}(E)$, in which two hard-collinear gluons are exchanged in the baryon constituents, can factorize into the soft and collinear matrix elements convoluted with a hard-kernel of order $α_s^2$. Including the energy release dependence, we derive the scaling law $ξ_{Λ,p}(E)\sim Λ^2 /E^2$. We also find that this form factor $ξ_Λ(E)$ is numerically smaller than the form factor governed by soft processes, although the latter is formally power-suppressed.
description: 18 pages, 2 figures, references and more discussions added; journal version
Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density
Creators: name: Sherrard-Smith, Ellie
name: Sala, Katarzyna A.
name: Betancourt, Michael Joseph
name: Upton, Leanna M.
name: Angrisano, Fiona
name: Morin, Merribeth J.
name: Ghani, Azra C.
name: Churcher, Thomas S.
name: Blagborough, Andrew M.
Publisher: name: Columbia University
Year: 2018
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Vaccines
subject: Malaria--Prevention
subject: Mosquitoes as carriers of disease
subject: Epidemiology

description: Anti-malarial pre-erythrocytic vaccines (PEV) target transmission by inhibiting human infection but are currently partially protective. It has been posited, but never demonstrated, that co-administering transmission-blocking vaccines (TBV) would enhance malaria control. We hypothesized a mechanism that TBV could reduce parasite density in the mosquito salivary glands, thereby enhancing PEV efficacy. This was tested using a multigenerational population assay, passaging Plasmodium berghei to Anopheles stephensi mosquitoes. A combined efficacy of 90.8% (86.7–94.2%) was observed in the PEV +TBV antibody group, higher than the estimated efficacy of 83.3% (95% CrI 79.1–87.0%) if the two antibodies acted independently. Higher PEV efficacy at lower mosquito parasite loads was observed, comprising the first direct evidence that co-administering anti-sporozoite and anti-transmission interventions act synergistically, enhancing PEV efficacy across a range of TBV doses and transmission intensities. Combining partially effective vaccines of differing anti-parasitic classes is a pragmatic, powerful way to accelerate malaria elimination efforts.
Heterodermia obscurata Trevis.
Creators: name: R, Jeanne dos
name: Silva, eis
name: Aptroot, André
name: E, Marcela
name: S, ugenia da
name: Cáceres, ilva
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Lecanoromycetes
Caliciales
Physciaceae
Heterodermia
Heterodermia obscurata

description: Heterodermia obscurata (Nyl.) Trevis.
PREVIOUS REPORT. — Mistry (1998).
NEW REPORT. — Parque Nacional de Brasília, on bark, leg. J.A.R. Silva, ISE 53413.
description: Published as part of R, Jeanne dos, Silva, eis, Aptroot, André, E, Marcela, S, ugenia da & Cáceres, ilva, 2023, Lichens from dry central Brazil: a checklist of lichenized fungi from Distríto Federal and Goiás, pp. 117-133 in Cryptogamie, Mycologie 20 (9) on page 120, DOI: 10.5252/cryptogamie-mycologie2023v44a9, http://zenodo.org/record/8434271
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels
Creators: name: Saponaro, Andrea
name: Cantini, Francesca
name: Porro, Alessandro
name: Bucchi, Annalisa
name: DiFrancesco, Dario
name: Maione, Vincenzo
name: Donadoni, Chiara
name: Introini, Bianca
name: Mesirca, Pietro
name: Mangoni, Matteo E.
name: Thiel, Gerhard
name: Banci, Lucia
name: Santoro, Bina
name: Moroni, Anna
Publisher: name: Columbia University
Year: 2018
Subjects: Biology
Cardiac pacemakers
Cyclic adenylic acid
Peptides
Molecular biology

description: Binding of TRIP8b to the cyclic nucleotide binding domain (CNBD) of mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels prevents their regulation by cAMP. Since TRIP8b is expressed exclusively in the brain, we envisage that it can be used for orthogonal control of HCN channels beyond the central nervous system. To this end, we have identified by rational design a 40-aa long peptide (TRIP8bnano) that recapitulates affinity and gating effects of TRIP8b in HCN isoforms (hHCN1, mHCN2, rbHCN4) and in the cardiac current If in rabbit and mouse sinoatrial node cardiomyocytes. Guided by an NMR-derived structural model that identifies the key molecular interactions between TRIP8bnano and the HCN CNBD, we further designed a cell-penetrating peptide (TAT-TRIP8bnano) which successfully prevented β-adrenergic activation of mouse If leaving the stimulation of the L-type calcium current (ICaL) unaffected. TRIP8bnano represents a novel approach to selectively control HCN activation, which yields the promise of a more targeted pharmacology compared to pore blockers.
title: Muscle coactivation can prime the nervous system for rapid feedback control
Creators: name: Maurus, Philipp
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Sensory Feedback
subject: Vision
subject: Proprioception
subject: Muscle Coactivation
subject: Sensorimotor Control
subject: Neuroscience

description: Humans often interact with environments where they may encounter disturbances that can vary in direction and amplitude between or within movement. In turn, these disturbances can threaten success of their actions. Recent advances in Optimal Feedback Control highlight the flexible use of sensory feedback when dealing with unpredictable disturbances. In this thesis, we investigated how features of the body or task alter how the healthy nervous system processes sensory feedback. Chapter 2 examined whether right-handed individuals (N=28) express differences in stretch responses when controlling the posture of the dominant and nondominant arms. Across two experiments, we found no differences in stretch responses between the two arms. Instead, behavioral and muscle responses correlated across arms. Chapter 3 tested whether participants (N=70) alter their responsiveness to sensory feedback when reaching in the presence of random, time-varying torque disturbances. Across three experiments, we demonstrated that participants increased and tuned their responses to proprioceptive and visual feedback as well as muscle coactivation to the variability of the random torque disturbances. Chapter 4 investigated whether participants (N=90) modulate their responsiveness to sensory feedback when exposed to unpredictable visuomotor rotations that can vary in amplitude and direction between reaching movements. Across three experiments, we showed that participants increased and tuned their responses to visual and proprioceptive feedback and muscle coactivation to the variability of the unpredictable visuomotor rotations. Moreover, increases in muscle coactivation correlated with the vigor of corrective responses to visual and proprioceptive feedback. Chapter 5 examined the role of muscle coactivation in upregulating responses to sensory feedback when initiating and controlling voluntary reaching movements. Across four experiments (N=80), we found that participants spontaneously increased muscle coactivation and responses to sensory feedback when the task imposed greater temporal urgency. Moreover, instructions to coactivate upregulated responses to visual, auditory, and somatosensory feedback and expedited the initiation and control of voluntary reaching movements. Collectively, the studies included in this thesis highlight the important role of muscle coactivation in upregulating responses to sensory feedback to provide mobility. The findings raise questions about the traditional role of muscle coactivation in leveraging viscoelastic properties of skeletal muscles to provide stability.
Saddle stresses for generic theories with a preferred acceleration scale
Creators: name: Magueijo, Joao
name: Mozaffari, Ali
Publisher: name: arXiv
Year: 2012
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: We show how scaling arguments may be used to generate templates for the tidal stresses around saddles for a vast class of MONDian theories {\it detached from their obligations as dark matter alternatives}. Such theories are to be seen simply as alternative theories of gravity with a preferred acceleration scale, and could be tested in the solar system by extending the LISA Pathfinder (LPF) mission. The constraints thus obtained may then be combined, if one wishes, with requirements arising from astrophysical and cosmological applications, but a clear separation of the issues is achieved. The central technical content of this paper is the derivation of a scaling prescription allowing complex numerical work to be bypassed in the generation of templates. We find that LPF could constrain very tightly the acceleration $a_0$ and the free parameter $κ$ present in these theories. As an application of our technique we also produce predictions for the moon saddle (for which a similar scaling argument is applicable) with the result that we recommend that it should be included in orbit design.
description: Analysis of the lunar saddle added to version to appear in Physical Review D
title: Epidemiology of Alcohol-Related Hepatitis, Alcohol-Related Cirrhosis, and Non-Alcohol-Related Cirrhosis in Alberta, Canada: An Administrative Data Validation and Population-Based Study
Creators: name: Swain, Liam Andrew
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Alcohol-related liver disease
subject: Cirrhosis
subject: Hospitalization
subject: ICD-10
subject: Administrative database
subject: COVID-19
subject: Epidemiology

description: Background: Population-based studies evaluating the epidemiology of chronic liver diseases rely on accurate case definitions. This thesis aimed to develop new coding algorithms for alcohol- (AC) and non-alcohol-related cirrhosis (NAC) to use alongside a previously validated alcohol-related hepatitis (AH) coding algorithm to examine population-level AC, NAC, and AH hospitalization rate trends from 2012-2022, in Alberta, Canada. Methods: Using a randomly selected cohort of 700 admissions with diagnostic codes for alcohol- and cirrhosis-related conditions from the 2008-2022 Calgary Discharge Abstract Database (DAD), we validated (using electronic medical record review) newly developed and commonly used AC/NAC case definitions. The newly validated coding algorithms were used to select all adult AC/NAC/AH hospitalizations in the Alberta DAD from 2012-2022. All admissions were postal code matched to the 2016 Alberta Census data aggregated to the DA level. Temporal trends in annual sex/age-standardized hospitalization rates per 100,000 Alberta population were examined using Joinpoint analysis stratified by sex, age, area-level income quartile, and rural/urban residency. Results: Our new AC algorithm selecting codes for AC, alcohol-related hepatic failure, or alcohol use disorder (AUD) with a decompensated cirrhosis condition or NAC code provided higher accuracy than previous methods (AUROC 0.88 vs. 0.50-0.81, p<0.001). Our new NAC algorithm, excluding AUD codes and selecting for a NAC or a primary decompensated cirrhosis condition code provided higher accuracy than previous approaches (AUORC 0.87 vs. 0.58-0.76, p<0.001). Using these new algorithms, we determined that between 2012-2022, AC hospitalization rates increased only for urban females, those <35 years of age, and for those living in regions with the highest area-level income. AH hospitalization rates increased predominantly for people <35 years and for females. During the COVID-19 pandemic AC/AH hospitalization rates significantly increased for those from rural and low-income areas. NAC hospitalization rates were not impacted by the COVID-19 pandemic, only increasing in people ≥65 years. Conclusions: The new case definitions exhibit enhanced AC/NAC identification accuracy compared to previous methods. Over the past decade, AC/AH hospitalizations increased in younger and female populations, and NAC hospitalizations steadily increased in older populations.
Inscribing a regular octahedron into polytopes
Creators: name: Akopyan, Arseniy
name: Karasev, Roman
Publisher: name: arXiv
Year: 2011
Subjects: subject: Combinatorics (math.CO)
subject: Metric Geometry (math.MG)
subject: FOS: Mathematics
subject: 52B10

description: We prove that any simple polytope (and some non-simple polytopes) in $\mathbb R^3$ admits an inscribed regular octahedron.
Hypotrachyna minarum Krog & Swinscow
Creators: name: R, Jeanne dos
name: Silva, eis
name: Aptroot, André
name: E, Marcela
name: S, ugenia da
name: Cáceres, ilva
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Fungi
Ascomycota
Lecanoromycetes
Lecanorales
Parmeliaceae
Hypotrachyna
Hypotrachyna minarum

description: Hypotrachyna minarum ( Vain.) Krog & Swinscow
PREVIOUS REPORT. — Mistry (1998).
NEW REPORT. — Parque Nacional de Brasília, on bark, leg. J.A.R. Silva, ISE 53290.
description: Published as part of R, Jeanne dos, Silva, eis, Aptroot, André, E, Marcela, S, ugenia da & Cáceres, ilva, 2023, Lichens from dry central Brazil: a checklist of lichenized fungi from Distríto Federal and Goiás, pp. 117-133 in Cryptogamie, Mycologie 20 (9) on page 121, DOI: 10.5252/cryptogamie-mycologie2023v44a9, http://zenodo.org/record/8434271
title: The Impact of Industry Cycles on Strategic Management of Human Capital: Three Empirical Studies
Creators: name: Wang, Ke
Publisher: name: Haskayne School of Business
Year: 2024
Subjects: subject: Strategic Management
subject: Human Capital
subject: Empirical Studies
subject: Gender Discrimination
subject: Acquisitions
subject: Business Administration--Management

description: Research on strategic human capital management (HCM) has concentrated on firm outcomes such as performance and competitive advantage. However, there is less understanding regarding the determinants of firms’ strategic behaviors in HCM. While the influence of context on firm behaviors has been well documented in the management literature, it has been under-researched in the specific realm of strategic HCM. This dissertation addresses how industry cycles, an important market context, affect firms' management of existing human capital regarding the treatment of women employees, and firms’ acquisition of human capital through human-assets-embodied (HAE) acquisitions. By using multilevel and longitudinal analyses the three empirical studies in this dissertation found determining effects of industry cycles on firms’ strategic behaviors in HCM. The results of the first study indicate that firms manage their tendencies for gender discrimination regarding differential punishment–referred to as the gender punishment gap– during downturns by imposing low-visibility punishments (through pay freezes) rather than high-visibility punishments (through layoffs) on top female leaders to mitigate reputation loss. The second study confirms firms’ higher likelihood to promote women into leadership positions during downturns than upturns–the glass cliff phenomenon– but highlights firms’ strategic consideration that only women who are top performers experience increased promotion chances during downturns. The third study shows that firms make HAE acquisitions more in upturns than downturns to meet their strategic priorities and take advantage of the benefits from human capital embodied in acquisitions. By emphasizing the influential effects of context on firms’ strategic decision-making, the three studies explain why and when firms undertake certain HCM practices, thereby deepening our understanding of firms’ strategic behaviors in human capital management. Therefore, the dissertation complements existing research on strategic HCM, which focuses on the outcomes of HCM behaviors. It also contributes to management practice by sensitizing business decision-makers to the important role of industry cycles in HCM practices.
Texts in Victorian Languages
Creators: name: Hercus, Luise (Ed.)
Publisher: name: Pacific Linguistics
Year: 1974

description: TEXTS IN VICTORIAN LANGUAGES. 13MAP 14PHOTOGRAPHS: 1. Guardians of Victorian Traditions 15 2. Mrs. Jackson Stuart 16 3. Mr. Jack Long 16 1. INTRODUCTION 17 2. THE STORY OF ORION: A MAḎIMAḎI VERSION 27 3. SHORT MAḎIMAḎI TEXTS 33 4. ABBREVIATIONS 41
Adsorbate Transport on Graphene by Electromigration
Creators: name: Solenov, Dmitry
name: Velizhanin, Kirill A.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Chemical functionalization of graphene holds promise for various applications ranging from nanoelectronics to catalysis, drug delivery, and nanoassembly. In many applications it is important to be able to transport adsorbates on graphene in real time. We propose to use electromigration to drive the adsorbate transport across the graphene sheet. To assess the efficiency of electromigration, we develop a tight-binding model of electromigration of an adsorbate on graphene and obtain simple analytical expressions for different contributions to the electromigration force. Using experimentally accessible parameters of realistic graphene-based devices as well as electronic structure theory calculations to parametrize the developed model, we argue that electromigration on graphene can be efficient. As an example, we show that the drift velocity of atomic oxygen covalently bound to graphene can reach ~1 cm/s.
title: Characterizing Plasma Biomarkers of Cerebral Amyloid Angiopathy
Creators: name: Muir, Ryan Thomas
Publisher: name: Graduate Studies
Year: 2024
Subjects: subject: Cerebral Amyloid Angiopathy
subject: Hemorrhagic Stroke
subject: Plasma Biomarkers
subject: Cerebral Small Vessel Disease
subject: Medicine and Surgery
subject: Epidemiology

description: BACKGROUND: Cerebral Amyloid Angiopathy (CAA) is characterized by the progressive deposition of beta-amyloid in cortical and leptomeningeal small vessels leading to hemorrhagic stroke and dementia. While CAA is diagnosed using Boston Criteria 2.0, they are not always possible to apply. Plasma biomarkers (Aβ42, Aβ40, phosphorylated-tau (p-tau), neurofilament light chain (NfL) and Glial Fibrillary Acidic Protein (GFAP)) might improve diagnostic accuracy. This study evaluates whether plasma biomarkers: (i) differ in CAA compared to controls (ii) discriminate a diagnosis of CAA individually and in combination and (iii) are associated with cognition and neuroimaging biomarkers. METHODS: Data are from a multi-centre cohort study of participants with probable CAA and healthy controls. Participants had plasma collected and underwent neurocognitive evaluation and magnetic resonance imaging. Aβ was quantified with two independent methods: immunoprecipitation mass-spectrometry (IPMS) and single molecule array assay (Simoa). Plasma p-tau181, NfL and GFAP were quantified with Simoa. Neuroimaging biomarkers of small vessel disease, atrophy, white matter integrity and cerebrovascular reactivity (CVR) were quantified. Logistic regression was used to compute areas under the receiver operating characteristic curve (AUC) to assess biomarker discriminative performance of ascertaining a diagnosis of CAA. Associations between plasma biomarkers, cognition and neuroimaging biomarkers were evaluated with generalized linear models. RESULTS: 45 participants with CAA and 47 controls were eligible. With both methods, the Aβ42/40 ratio was reduced in CAA compared to controls. Furthermore, those with CAA had elevated p-tau181 and NfL. A combination of Aβ42/40 (Simoa), p-tau181, and NfL resulted in an AUC of 0.90. Reduced Aβ42/40 was associated with poorer speed of processing. Increasing NfL was associated with reduced Montreal Cognitive Assessment Scores, lower CVR and increasing CAA severity. CONCLUSIONS: This study identified differences in plasma Aβ42/40, p-tau181 and NfL in CAA compared and provides evidence that a panel of these biomarkers can achieve excellent diagnostic discriminability. This study also demonstrates that a marker of cerebral amyloidosis (Aβ42/40) is associated with speed of processing difficulties in those with CAA, while NfL was associated with global cognition, CAA severity and CVR. Overall, plasma biomarkers might, in future, help improve the evaluation and detection of CAA.
The role of the geometric phases in adiabatic populations tracking for non-hermitian hamiltonians
Creators: name: Leclerc, Arnaud
name: Viennot, David
name: Jolicard, Georges
Publisher: name: arXiv
Year: 2012
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We show that the definition of instantaneous eigenstate populations for a dynamical non-self-adjoint system is not obvious. The naive direct extension of the definition used for the self-adjoint case leads to inconsistencies; the resulting artifacts can induce a false inversion of population or a false adiabaticity. We show that the inconsistency can be avoided by introducing geometric phases in another possible definition of populations. An example is given which demonstrates both the anomalous effects and their removal by our approach.
description: 15 pages, 8 figures