cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The strength of smoothed particle hydrodynamics in modelling binary interactions
Creators: name: Reichardt, Thomas
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The common envelope interaction gives rise to the formation of close binaries comprising at least one evolved star, such as a white dwarf. The idea behind the common envelope interaction is attractively simple. However, hidden complexities hav prevented a full understanding of the interaction. Hydrodynamic simulations of this interaction have been pivotal in gaining an understanding of compact binary systems and phenomena that may result from them, such as novae and x-ray binaries. Unfortunately, notable disagreements still exist amongst simulations and between simulated parameters of post-common envelope binaries and observations, such as diﬀering ﬁnal separations. In this work, we perform common envelope simulations with a new smoothed particle hydrodynamics code, Phantom, which has never been trained on this problem before. The lack of a simulation domain boundary, along with excellent conservation of energy and angular momentum, allows us to track the interaction in its entirety. We start by reproducing the simulations of Passy et al. (2012) to calibrate the code. Phantom is then used to carry out preliminary simulations of the phases preceding the fast inspiral and its eﬀects on later stages of the interaction. We also investigated how bound gas that falls back onto the binary after the inspiral phase, leading to a new interaction. Although some computational issues remain to be resolved, Phantom has thus far proved to be an excellent tool in the study of binary interactions.
Was 49b: An Overmassive AGN in a Merging Dwarf Galaxy?
Creators: name: Secrest, Nathan J.
name: Schmitt, Henrique R.
name: Blecha, Laura
name: Rothberg, Barry
name: Fischer, Jacqueline
Publisher: name: arXiv
Year: 2016
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We present a combined morphological and X-ray analysis of Was 49, an isolated, dual AGN system notable for the presence of a dominant AGN Was 49b in the disk of the primary galaxy Was 49a, at a projected radial distance of 8 kpc from the nucleus. Using X-ray data from Chandra, NuSTAR, and Swift, we find that this AGN has a bolometric luminosity of L_bol ~ 2 x 10^45 erg/s, with a black hole mass of M_BH=1.3^{+2.9}_{-0.9} x 10^8 M_Sol. Despite its large mass, our analysis of optical data from the Discovery Channel Telescope shows that the supermassive black hole is hosted by a stellar counterpart with a mass of only 5.6^{+4.9}_{-2.6} x 10^9 M_Sol, making the SMBH potentially larger than expected from SMBH-galaxy scaling relations, and the stellar counterpart exhibits a morphology that is consistent with dwarf elliptical galaxies. Our analysis of the system in the r and K bands indicates that Was 49 is a minor merger, with a mass ratio of Was 49a to Was 49b between 1:7 and 1:15. This is in contrast with findings that the most luminous merger-triggered AGNs are found in major mergers, and that minor mergers predominantly enhance AGN activity in the primary galaxy.
description: 11 pages, 6 figures, accepted for publication in ApJ
The Current Practices of Knowledge Economy in the United Arab Emirates in the Government Institution and Economic Pillar.
Creators: name: Nusairi, Asmaa
Publisher: name: figshare
Year: 2022
Subjects: subject: 140213 Public Economics- Public Choice
subject: FOS: Economics and business

description: This article explains the current practices of the knowledge economy in the United Arab Emirates in the Government Institutions and Economic Incentives Pillar according to the World Bank framework of Knowledge Economy
Massless Dirac Fermions Trapping in a Quasi-one-dimensional npn Junction of a Continuous Graphene Monolayer
Creators: name: Bai, Ke-Ke
name: Qiao, Jia-Bin
name: Jiang, Hua
name: Liu, Haiwen
name: He, Lin
Publisher: name: arXiv
Year: 2017
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: Massless Dirac fermions in graphene provide unprecedented opportunities to realize the Klein paradox, which is one of the most exotic and striking properties of relativistic particles. In the seminal theoretical work [Katsnelson et al., Nat. Phys. 2 620 (2006)], it was predicted that the massless Dirac fermions can pass through one-dimensional (1D) potential barriers unimpededly at normal incidence. Such a result seems to preclude confinement of the massless Dirac fermions in graphene by using 1D potential barriers. Here, we demonstrate, both experimentally and theoretically, that massless Dirac fermions can be trapped in quasi-1D npn junction of a continuous graphene monolayer. Because of highly anisotropic transmission of the massless Dirac fermions at n-p junction boundaries (the so-called Klein tunneling in graphene), charge carries incident at large oblique angles will be reflected from one edge of the junction with high probability and continue to bounce from the opposite edge. Consequently, these electrons are trapped for a finite time to form quasi-bound states in the quasi-1D npn junction. The quasi-bound states seen as pronounced resonances are probed and the quantum interference patterns arising from these states are directly visualized in our scanning tunneling microscope measurements.
description: 4 Figures in main text
Additional file 1: of Constraint-based perturbation analysis with cluster Newton method: a case study of personalized parameter estimations with irinotecan whole-body physiologically based pharmacokinetic model
Creators: name: Asami, Shun
name: Kiga, Daisuke
name: Konagaya, Akihiko
Publisher: name: figshare
Year: 2017
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: A simple model for parameter estimations with and without constraint. We explain our approach of parameter estimation with or without constraint in this file. (PDF 180 kb)
Anthropogenic influence on symbiotic interactions of Australian sea lions (Neophoca cinerea)
Creators: name: Delport, Tiffany Claire
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Interactions between humans, domestic animals and wildlife populations present an interface for the dissemination of microorganisms. The spread of disease-causing microorganisms can have serious impacts to the health and population dynamics of vulnerable marine wildlife species, particularly those that aggregate in high-density colonies. Therefore, understanding microorganism dissemination at this interface is crucial for the long-term conservation of endangered marine species. Genetic characterization of indicator microorganisms provides a means with which to monitor dissemination of microorganisms of anthropogenic origin. Currently, accurate inferences detailing microorganism transmission routes to wildlife populations at this interface are limited by the low availability of genomic data. I used molecular tools to investigate potential anthropogenic impacts on an endangered endemic marine mammal, the Australian sea lion (Neophoca cinerea), a species whose contemporary disease ecology is largely unstudied. The sea lions’ natural habitat encompasses coastal islands experiencing constant human visitation through to almost completely isolated islands, making the species ideal for the assessment of organism dissemination from anthropogenic sources. Through protozoal and microbial monitoring, I aimed to determine the establishment of terrestrial and human originated organisms in wild versus captive Australian sea lions. Screening for protozoan parasites identified Giardia duodenalis genotypes prominent in human infection in greater frequency in sea lions within close proximity to human settlements compared to more isolated colonies. Cryptosporidium was not detected in sea lion populations. Microbial monitoring indicated similar findings, with the presence of E. coli harbouring integronborne antibiotic resistance mechanisms commonly identified in clinical settings, significantly greater in captive animals. Finally, the application of next-generation sequencing indicated a high level of dissimilarity of microbiota community structure and membership between wild and captive animals. The genetic tools and target indicators described in this thesis can be applied to determine the dissemination of microorganisms from anthropogenic sources in most marine wildlife taxa. Through the identification of target indicators, we can bridge knowledge gaps in microorganism movement, and, as a result, better inform long-term conservation management strategies aimed at reducing anthropogenic impacts to sensitive marine mammal populations.
Discovery of Scattering Polarization in the Hydrogen Lyman-$α$ Line of the Solar Disk Radiation
Creators: name: Kano, R.
name: Bueno, J. Trujillo
name: Winebarger, A.
name: Auchère, F.
name: Narukage, N.
name: Ishikawa, R.
name: Kobayashi, K.
name: Bando, T.
name: Katsukawa, Y.
name: Kubo, M.
name: Ishikawa, S.
name: Giono, G.
name: Hara, H.
name: Suematsu, Y.
name: Shimizu, T.
name: Sakao, T.
name: Tsuneta, S.
name: Ichimoto, K.
name: Goto, M.
name: Belluzzi, L.
name: Štěpán, J.
name: Ramos, A. Asensio
name: Sainz, R. Manso
name: Champey, P.
name: Cirtain, J.
name: De Pontieu, B.
name: Casini, R.
name: Carlsson, M.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: There is a thin transition region (TR) in the solar atmosphere where the temperature rises from 10,000 K in the chromosphere to millions of degrees in the corona. Little is known about the mechanisms that dominate this enigmatic region other than the magnetic field plays a key role. The magnetism of the TR can only be detected by polarimetric measurements of a few ultraviolet (UV) spectral lines, the Lyman-$α$ line of neutral hydrogen at 121.6 nm (the strongest line of the solar UV spectrum) being of particular interest given its sensitivity to the Hanle effect (the magnetic-field-induced modification of the scattering line polarization). We report the discovery of linear polarization produced by scattering processes in the Lyman-$α$ line, obtained with the Chromospheric Lyman-Alpha Spectro-Polarimeter (CLASP) rocket experiment. The Stokes profiles observed by CLASP in quiet regions of the solar disk show that the $Q/I$ and $U/I$ linear polarization signals are of the order of 0.1 % in the line core and up to a few percent in the nearby wings, and that both have conspicuous spatial variations with scales of $\sim 10$ arcsec. These observations help constrain theoretical models of the chromosphere-corona TR and extrapolations of the magnetic field from photospheric magnetograms. In fact, the observed spatial variation from disk to limb of polarization at the line core and wings already challenge the predictions from three-dimensional magnetohydrodynamical models of the upper solar chromosphere.
title: ADCO, Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Cart. 198-01 (11 H 1055), 185 folios, f. 0248
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2019
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: cartulaire
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0248, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire de Cîteaux pour les domaines de Saint-Jean de Losne et Losne (XVIIIe siècle), Archives départementales de la Côte-d'Or, Cart. 198-01 (11 H 1055), 185 folios, f. 0248, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Discovery of the most metal-poor damped Lyman-alpha system
Creators: name: Cooke, Ryan
name: Pettini, Max
name: Steidel, Charles C.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We report the discovery and analysis of the most metal-poor damped Lyman-alpha (DLA) system currently known, based on observations made with the Keck HIRES spectrograph. The metal paucity of this system has only permitted the determination of three element abundances: [C/H] = -3.43 +/- 0.06, [O/H] = -3.05 +/- 0.05, and [Si/H] = -3.21 +/- 0.05, as well as an upper limit on the abundance of iron: [Fe/H] < -2.81. This DLA is among the most carbon-poor environment currently known with detectable metals. By comparing the abundance pattern of this DLA to detailed models of metal-free nucleosynthesis, we find that the chemistry of the gas is consistent with the yields of a 20.5 M_sun metal-free star that ended its life as a core-collapse supernova; the abundances we measure are inconsistent with the yields of pair-instability supernovae. Such a tight constraint on the mass of the progenitor Population III star is afforded by the well-determined C/O ratio, which we show depends almost monotonically on the progenitor mass when the kinetic energy of the supernova explosion is E_exp > 1.5x10^51 erg. We find that the DLA presented here has just crossed the critical 'transition discriminant' threshold, rendering the DLA gas now suitable for low mass star formation. We also discuss the chemistry of this system in the context of recent models that suggest some of the most metal-poor DLAs are the precursors of the 'first galaxies', and are the antecedents of the ultra-faint dwarf galaxies.
description: 10 pages, 5 figures, Accepted for publication in Monthly Notices of the Royal Astronomical Society
MOESM1 of Prostate cancer small non-coding RNA transcriptome in Arabs
Creators: name: Jingxuan Shan
name: Al-Rumaihi, Khalid
name: Chouchane, Karim
name: Al-Bozom, Issam
name: Rabah, Danny
name: Farhat, Karim
name: Chouchane, Lotfi
Publisher: name: figshare
Year: 2017
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer

description: Additional file 1: Figure S1. Average NGS reads length distribution Q:Qatar S: Saudi Arabia N: Non-tumor T: Tumor. Figure S2. Scatter Plot of miRNAs in each pair of samples. Each point represents a miRNA. The X axis and Y axis show expression level of miRNAs in tumor and non-tumor tissues respectively. Red points represents miRNAs with ratio > 2; blue points represents miRNAs with 1/2
Landscape genetic connectivity and sex-specific responses in a range expanding damselfly
Creators: name: Carey, Alexander Robert
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Range shifts induced by climate change have been documented in many insect taxa. The damselfly, Ischnura elegans, is undergoing a poleward range expansion in northern Europe showing local adaptation to environmental conditions at the range edge in Sweden. However,the role of neutral genetic connectivity and sex-specific responses in the range expansion process is unknown. We examine relative abundance, sex-specific landscape genetic relationships and morphological variation in I. elegans along a ~600km range expansion axis. We analysed 29 landscape resistance surfaces against genetic distances (FST and G`ST) calculated from 3,554 RAD seq-derived neutral Single Nucleotide Polymorphisms (SNPs) from 25 sites (n = 426 individuals). Resistance modelling showed cooler mean annual temperatures limited genetic connectivity linearly, with greater resistance at colder range limit sites. Relative site abundances were reduced along the sampled gradient; however,genetic diversity showed no significant change, suggesting recent colonisations. Results were consistent with female-biased dispersal, with females showing reduced temperature resistance to gene flow and a small, almost linear effect of land cover type that was not observed in males. Female, but not male, wing length also increased towards the range limit. Our findings demonstrate sex-specific morphological and landscape genetic responses during a climate-change induced range expansion.
Observational signatures of past mass-exchange episodes in massive binaries: The case of LSS 3074
Creators: name: Raucq, F.
name: Gosset, E.
name: Rauw, G.
name: Manfroid, J.
name: Mahy, L.
name: Mennekens, N.
name: Vanbeveren, D.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The role of mass and momentum exchanges in close massive binaries is very important in the subsequent evolution of the components. Such exchanges produce several observational signatures such as asynchronous rotation and altered chemical compositions, that remain after the stars detach again. We investigated these effects for the close O-star binary LSS 3074 (O4 f + O6-7 :(f):), which is a good candidate for a past Roche lobe overflow (RLOF) episode because of its very short orbital period, P = 2.185 days, and the luminosity classes of both components. We determined a new orbital solution for the system. We studied the photometric light curves to determine the inclination of the orbit and Roche lobe filling factors of both stars. Using phase-resolved spectroscopy, we performed the disentangling of the optical spectra of the two stars. We then analysed the reconstructed primary and secondary spectra with the CMFGEN model atmosphere code to determine stellar parameters, such as the effective temperatures and surface gravities, and to constrain the chemical composition of the components. We confirm the apparent low stellar masses and radii reported in previous studies. We also find a strong overabundance in nitrogen and a strong carbon and oxygen depletion in both primary and secondary atmospheres, together with a strong enrichment in helium of the primary star. We propose several possible evolutionary pathways through a RLOF process to explain the current parameters of the system. We confirm that the system is apparently in overcontact configuration and has lost a significant portion of its mass to its surroundings. We suggest that some of the discrepancies between the spectroscopic and photometric properties of LSS 3074 could stem from the impact of a strong radiation pressure of the primary.
A direct realist understanding of memory errors
Creators: name: Chew, Li Mei
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: Memory errors are part and parcel of everyday remembering. While memory and errors in general, present as some of strongest evidence in support for representationalism, memory and error are also two of bigger challenges for direct realism. In fact, critics regard both memory and errors as insurmountable logical problems for direct realism, which makes memory error a unique challenge for direct realism. With regards to memory, firstly, the problem is if the direct realist claims that remembering is a direct relation to a past event, how does the subject who is engaged in the present act of remembering have direct relation to a past event that no long exists? With regard to error, the problem is that if there is a direct relation to the object of cognition as direct realism claims then what is the object of cognition when we are in error? In the case of memory errors then, the challenge is that not only is the act of remembering taking place separate from the initial time the event has occurred but the direct realist needs also to account for how the subject, who has a direct independent relation to the event, can be mistaken about the past event he or she is remembering. The present thesis aim is to take steps to show how direct realist will take the first steps to address the problems of memory error. It will be shown that a variety of direct realism known as situational realism that defines psychology as the study of organism environmental relations and the interactions involving cognition, emotion, and motivation will be able to address the challenges. It will be argued that it is only by taking into consideration both memory and error together that a greater sense of error can be understood from a direct realist perspective.
The OGLE Collection of Variable Stars. Over 450 000 Eclipsing and Ellipsoidal Binary Systems Toward the Galactic Bulge
Creators: name: Soszyński, I.
name: Pawlak, M.
name: Pietrukowicz, P.
name: Udalski, A.
name: Szymański, M. K.
name: Wyrzykowski, Ł.
name: Ulaczyk, K.
name: Poleski, R.
name: Kozlowski, S.
name: Skowron, D. M.
name: Skowron, J.
name: Mróz, P.
name: Hamanowicz, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: We present a collection of 450 598 eclipsing and ellipsoidal binary systems detected in the OGLE fields toward the Galactic bulge. The collection consists of binary systems of all types: detached, semi-detached, and contact eclipsing binaries, RS CVn stars, cataclysmic variables, HW Vir binaries, double periodic variables, and even planetary transits. For all stars we provide the I- and V-band time-series photometry obtained during the OGLE-II, OGLE-III, and OGLE-IV surveys. We discuss methods used to identify binary systems in the OGLE data and present several objects of particular interest.
description: 16 pages, 9 figures
Core shift effect in blazars
Creators: name: Agarwal, A.
name: Mohan, P.
name: Gupta, Alok C.
name: Mangalam, A.
name: Volvach, A. E.
name: Aller, M. F.
name: Aller, H. D.
name: Gu, M. F.
name: Lahteenmaki, A.
name: Tornikoski, M.
name: Volvach, L. N.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We studied the pc-scale core shift effect using radio light curves for three blazars, S5 0716+714, 3C 279 and BL Lacertae, which were monitored at five frequencies ($ν$) between 4.8 GHz and 36.8 GHz using the University of Michigan Radio Astronomical Observatory (UMRAO), the Crimean Astrophysical Observatory (CrAO), and Metsahovi Radio Observatory for over 40 years. Flares were Gaussian fitted to derive time delays between observed frequencies for each flare ($Δt$), peak amplitude ($A$), and their half width. Using $A \propto ν^α$ we infer $α$ in the range $-$16.67 to 2.41 and using $Δt \propto ν^{1/k_r}$, we infer $k_r \sim 1$, employed in the context of equipartition between magnetic and kinetic energy density for parameter estimation. From the estimated core position offset ($Ω_{r ν}$) and the core radius ($r_{\rm core}$), we infer that opacity model may not be valid in all cases. The mean magnetic field strength at 1 pc ($B_1$) and at the core ($B_{\rm core}$), are in agreement with previous estimates. We apply the magnetically arrested disk model to estimate black hole spins in the range $0.15-0.9$ for these blazars, indicating that the model is consistent with expected accretion mode in such sources. The power law shaped power spectral density has slopes $-$1.3 to $-$2.3 and is interpreted in terms of multiple shocks or magnetic instabilities.
description: 21 pages, 17 figures, 12 tables. Accepted for publication in MNRAS
title: A Systematic Review of Same-Sex Sexual Behaviors Across Primates
Creators: name: Tripp, Hannah Chapman
name: Reddy, Rachna
name: Cunningham, Elizabeth
name: Voyt, Rachel
name: Benitez, Marcela E
name: Sandel, Aaron
Publisher: name: OSF Registries
Year: 2023
Subjects: subject: Life Sciences
subject: Social and Behavioral Sciences
subject: bias
subject: nonhuman primates
subject: same-sex behavior
subject: sexual behavior
subject: systematic review

description: This review seeks to answer the following questions: 1) What historical, taxonomic, or other biases exist among studies of same sex sexual behavior in primates that shape the patterns we report? 2) How widespread are same-sex sexual or “socio-sexual” behaviors in nonhuman primates? 3) How do these behaviors vary within and between sexes, populations, and species?
Effect of phosphorylation on the structure and dynamics of cardiac troponin protein complex: a molecular view of the regulation of heart muscle under stress conditions
Creators: name: Kachooei, Ehsan
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: The contraction of cardiac muscle is regulated by a large heterotrimeric complex, ~80 kDa, which is called 'Troponin' (Tn). Tn is located on the thin filament of striated muscle, playing a switch role in response to Ca2+ binding, to regulate the interaction of myosin with actin. The force of Ca2+ binding can initiate a series of conformational changes in the dynamic structure of the Tn complex which then propagate through the other components of the muscle filament, leading to contraction. Upon stress condition, and in response to β-adrenergic stimulations, Tn becomes phosphorylated in the heart which results in a faster relaxation and higher rate of contraction. Despite the wealth of structural data on troponin, the molecular details of the conformational changes triggered by Ca2+ binding and phosphorylation within the intact Tn complex is still lacking and remains an experimental challenge. In this Thesis, site directed spin labeling (SDSL), using paramagnetic nitroxide, in conjugation with Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR) was used to address fundamental questions about the structure and dynamics of the cardiac troponin complex upon phosphorylation. Long‐range (10-25 Å) structural information was derived from Paramagnetic Relaxation Enhancement (PRE) effects of the NMR signal due to the presence of the nitroxide spin label. Interspin distances were also obtained from continuous wave (8 -25 Å) and pulsed EPR (DEER, up to ~70 Å) techniques. Together, both magnetic resonance approaches provided us with a structural model that details the conformational interplay between key regions of the cardiac troponin complex in response to both Ca2+ binding and phosphorylation. Knowledge of the role of phosphorylation as a secondary regulatory mechanism in fine‐tuning the cardiac Tn isoform is important for understanding why cardiac muscle is perturbed by mutations that lead to disease states such as cardiomyopathy.
title: ADCO, Grènetier de Cîteaux : comptes (1499-1503) (11 H 1173), f. 00686
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2019
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: comptes

description: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Grènetier de Cîteaux : comptes (1499-1503), Archives départementales de la Côte-d'Or, (11 H 1173), f. 00686, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https://manuscrits.cbma-project.eu/
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
Exact solution for the force-extension relation of a semiflexible polymer under compression
Creators: name: Kurzthaler, Christina
name: Franosch, Thomas
Publisher: name: arXiv
Year: 2017
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Exact solutions for the elastic and thermodynamic properties for the wormlike chain model are elaborated in terms of Mathieu functions. The smearing of the classical Euler buckling instability for clamped polymers is analyzed for the force-extension relation. Interestingly, at strong compression forces the thermal fluctuations lead to larger elongations than for the elastic rod. The susceptibility defined as the derivative of the force-extension relation displays a prominent maximum at a force that approaches the critical Euler buckling force as the persistence length is increased. We also evaluate the excess entropy and heat capacity induced by the compresssion and find that they vary non-monotonically with the load. These findings are corroborated by pseudo-Brownian simulations.
description: 13 pages, Physical Review E
Additional file 1: of Research capacity building integrated into PHIT projects: leveraging research and research funding to build national capacity
Creators: name: Hedt-Gauthier, Bethany
name: Chilengi, Roma
name: Jackson, Elizabeth
name: Michel, Cathy
name: Napua, Manuel
name: Jackline Odhiambo
name: Ayaga Bawah
Publisher: name: figshare
Year: 2017
Subjects: subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Marine Biology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: PHIT Cross-site paper on Research Capacity Building Data Collection Form Round 1 of Data Collection. (DOCX 36Â kb)
Discovery of ferromagnetism with large magnetic anisotropy in ZrMnP and HfMnP
Creators: name: Lamichhane, Tej N.
name: Taufour, Valentin
name: Masters, Morgan W.
name: Parker, David S.
name: Kaluarachchi, Udhara S.
name: Thimmaiah, Srinivasa
name: Bud'ko, Sergey L.
name: Canfield, Paul C.
Publisher: name: arXiv
Year: 2016
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: ZrMnP and HfMnP single crystals are grown by a self-flux growth technique and structural as well as temperature dependent magnetic and transport properties are studied. Both compounds have an orthorhombic crystal structure. ZrMnP and HfMnP are ferromagnetic with Curie temperatures around $370$~K and $320$~K respectively. The spontaneous magnetizations of ZrMnP and HfMnP are determined to be $1.9$~$μ_\textrm{B}$/f.u. and $2.1$~$μ_\textrm{B}$/f.u. respectively at $50$~K. The magnetocaloric effect of ZrMnP in term of entropy change ($ΔS$) is estimated to be $-6.7$ kJm$^{-3}$K$^{-1}$ around $369$~K. The easy axis of magnetization is [100] for both compounds, with a small anisotropy relative to the [010] axis. At $50$~K, the anisotropy field along the [001] axis is $\sim4.6$~T for ZrMnP and $\sim10$~T for HfMnP. Such large magnetic anisotropy is remarkable considering the absence of rare-earth elements in these compounds. The first principle calculation correctly predicts the magnetization and hard axis orientation for both compounds, and predicts the experimental HfMnP anisotropy field within 25 percent. More importantly, our calculations suggest that the large magnetic anisotropy comes primarily from the Mn atoms suggesting that similarly large anisotropies may be found in other 3d transition metal compounds.
Roots Structure and Development of Austrobaileya scandens (Austrobaileyaceae) and Implications for Their Evolution in Angiosperms
Creators: name: Bachelier, Julien B.
name: Razik, Imran
name: Schauer, Maria
name: Seago, James L.
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: ANA grade
subject: Austrobaileyales
subject: common initials
subject: magnoliids
subject: open meristem
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; Biologie
subject: 500 Naturwissenschaften und Mathematik::580 Pflanzen (Botanik)::580 Pflanzen (Botanik)

description: Since the resolution of the ANA grade [Amborellales, Nymphaeales, Austrobaileyales] as sister to all other flowering plants, a few comparative studies of root structure have suggested that some of their anatomical traits could be of importance to understanding root evolutionary development and angiosperm phylogeny. However, there is still a paucity of information on root structure and apical meristems (RAMs) in these lineages and especially the sister to all other Austrobaileyales, Austrobaileya scandens. We used microtome sections and bright field, epifluorescence, laser confocal, and scanning electron microscopy to study adventitious root RAMs and tissues of A. scandens. Our results indicate that root structure is relatively simple in A. scandens. The epidermis has a thick cuticle and lacks root hairs. The stele is typically diarch, or some modification thereof, and surrounded by a cortex differentiated into a uniseriate endodermis, a middle region sometimes packed with starch, some oil cells, and colonized by arbuscular mycorrhizal fungi, and a multiseriate exodermis. Secondary growth produced many vessel elements in the secondary xylem and scattered sclerenchymatous fibers in secondary phloem. The absence of distinct patterning within the RAM and between the RAM and derivative differentiating tissues shows that the RAM is open and characterized by common initials. Roots structure and anatomy of A. scandens are thus essentially similar to some previously described in Amborella or Illicium in the ANA grade and many magnoliids, and suggest that the first woody flowering plants likely had an open RAM with common initials. Their functional and evolutionary significance in woody early-diverging and basal lineages of flowering plants and gymnosperms remains unclear, but they are clearly ancestral traits.
Supplementary Information from "Insights into the aggregation mechanism of RRM domains in TDP-43: A theoretical exploration" from Insights into the aggregation mechanism of RNA recognition motif domains in TDP-43: a theoretical exploration
Creators: name: Liu, Wei
name: Li, Chaoqun
name: Shan, Jiankai
name: Wang, Yan
name: Chen, Guangju
Publisher: name: The Royal Society
Year: 2021

description: Molecular dynamics simulation protocols, ZDOCK method detail and MM-PBSA results of tetramers and hexamer.
Gravitational waves from dark first order phase transitions and dark photons
Creators: name: Addazi, Andrea
name: Marciano, Antonino
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Cold Dark Matter particles may interact with ordinary particles through a dark photon, which acquires a mass thanks to a spontaneous symmetry breaking mechanism. We discuss a dark photon model in which the scalar singlet associated to the spontaneous symmetry breaking has an effective potential that induces a first order phase transition in the early Universe. Such a scenario provides a rich phenomenology for electron-positron colliders and gravitational waves interferometers, and may be tested in several different channels. The hidden first order phase transition implies the emission of gravitational waves signals, which may constrain the dark photon's space of parameters. Compared limits from electron-positron colliders, astrophysics, cosmology and future gravitational waves interferometers such as eLISA, U-DECIGO and BBO are discussed. This highly motivates a {\it cross-checking strategy} of data arising from experiments dedicated to gravitational waves, meson factories, the International Linear Collider (ILC), the Circular Electron Positron Collider (CEPC) and other underground direct detection experiments of cold dark matter candidates.
description: 5 pages, 2 figures
Bio-Inspired Amphiphilic Block-Copolymers Based on Synthetic Glycopolymer and Poly(Amino Acid) as Potential Drug Delivery Systems
Creators: name: Levit, Mariia
name: Zashikhina, Natalia
name: Vdovchenko, Alena
name: Dobrodumov, Anatoliy
name: Zakharova, Natalya
name: Kashina, Anna
name: Rühl, Eckart
name: Lavrentieva, Antonina
name: Scheper, Thomas
name: Tennikova, Tatiana
name: Korzhikova-Vlakh, Evgenia
Publisher: name: Freie Universität Berlin
Year: 2020
Subjects: subject: synthetic glycopolymers
subject: poly(amino acids)
subject: amphiphilic block copolymers
subject: modification of terminal groups
subject: nanoparticles
subject: redox-responsive systems
subject: paclitaxel
subject: drug delivery systems
subject: 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften

description: In this work, a method to prepare hybrid amphiphilic block copolymers consisting of biocompatible synthetic glycopolymer with non-degradable backbone and biodegradable poly(amino acid) (PAA) was developed. The glycopolymer, poly(2-deoxy-2-methacrylamido-D-glucose) (PMAG), was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. Two methods for modifying the terminal dithiobenzoate-group of PMAG was investigated to obtain the macroinitiator bearing a primary aliphatic amino group, which is required for ring-opening polymerization of N-carboxyanhydrides of hydrophobic α-amino acids. The synthesized amphiphilic block copolymers were carefully analyzed using a set of different physico-chemical methods to establish their composition and molecular weight. The developed amphiphilic copolymers tended to self-assemble in nanoparticles of different morphology that depended on the nature of the hydrophobic amino acid present in the copolymer. The hydrodynamic diameter, morphology, and cytotoxicity of polymer particles based on PMAG-b-PAA were evaluated using dynamic light scattering (DLS) and transmission electron microscopy (TEM), as well as CellTiter-Blue (CTB) assay, respectively. The redox-responsive properties of nanoparticles were evaluated in the presence of glutathione taken at different concentrations. Moreover, the encapsulation of paclitaxel into PMAG-b-PAA particles and their cytotoxicity on human lung carcinoma cells (A549) and human breast adenocarcinoma cells (MCF-7) were studied.
Elastic Scattering Phenomenology
Creators: name: Mackintosh, R. S.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Nuclear Theory (nucl-th)
subject: Nuclear Experiment (nucl-ex)
subject: FOS: Physical sciences

description: We argue that, in many situations, fits to elastic scattering data that were historically, and frequently still are, considered `good', are not justifiably so describable. Information about the dynamics of nucleon-nucleus and nucleus-nucleus scattering is lost when elastic scattering phenomenology is insufficiently ambitious. It is argued that in many situations, an alternative approach is appropriate for the phenomenology of nuclear elastic scattering of nucleons and other light nuclei. The approach affords an appropriate means of evaluating folding models, one that fully exploits available empirical data. It is particularly applicable for nucleons and other light ions.
description: 10 pages
Additional file 1 of OptPipe - a pipeline for optimizing metabolic engineering targets
Creators: name: AndrĂĄs Hartmann
name: Vila-Santa, Ana
name: Kallscheuer, Nicolai
name: Vogt, Michael
name: Julien-LaferriĂ¨Re, Alice
name: Marie-France Sagot
name: Marienhagen, Jan
name: Vinga, Susana
Publisher: name: figshare
Year: 2017
Subjects: subject: Space Science
subject: Medicine
subject: Molecular Biology
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Computational Biology

description: OptPipe - Supplementary Methods. Optimization algorithms and pipeline description. (PDF 189 kb)
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials
Creators: name: Alla, Sai Santhosha Mrudula
name: Shah, Dhruv J.
name: Ratheesh, Vysakh
name: Alla, Deekshitha
name: Tummala, Thanmayee
name: Khetan, Moksh S.
name: Shah, Ritika J.
name: Bayeh, Ruth G.
name: Fatima, Mahek
name: Ahmed, Sanah K.
name: Sabıroğlu, Mert
Publisher: name: Taylor & Francis
Year: 2024
Subjects: Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Science Policy

description: People living with HIV (PLWH) receiving statin therapy have shown improved lipid profiles. However, they are not free from side effects, thereby requiring strict monitoring of the therapy. The meta-analysis aims to analyze the effect of statins in PLWH and critically appraise the effectiveness of statin therapy in PLWH. PubMed, Scopus, and Web of Science servers were used to conduct a systematic search in compliance with the PRISMA guidelines. The meta-analysis of pooled effect estimates is produced using Revman software. A total of 12 RCTs with 8716 participants were included in the analysis. Analysis of the overall effect estimates found that statins resulted in a mean reduction of 41.15 mg/dl (MD = −41.15; 95% CI: −44.19, −38.11; p < 0.00001), 34.99 mg/dl (MD = −34.99; 95% CI: −34.99; 95% CI: −41.16, −28.82; p < 0.00001), and 7.36 mg/dl (MD = −7.36; 95% CI = −48.35, −33.62; p < 0.00001) in total cholesterol, low-density lipoprotein, and triglyceride levels, respectively. It is revealed that statins are associated with a significant increase in the discontinuation rate of treatment compared to placebo treatment (RR: 1.90; 95% CI: 1.36–2.65; p = 0.0002). When considered collectively, statin therapy’s advantages appear to exceed its occasional predictable side effects like liver or muscle toxicity. PROSPERO registration ID: CRD42023469521.
Does financial development cause economic growth: a case study of Nepal
Creators: name: Uprety, Dilli
Publisher: name: Macquarie University
Year: 2022
Subjects: Other education not elsewhere classified

description: A large number of studies have been conducted to investigate the association between financial development and economic growth. However, whilst these studies have found substantial evidence to support the notion that financial development has a positive impact on growth; a remarkable knowledge gap reamins - on casual direction, and on the ways in which country specific policies and institutions influence the findings. Into this milieu, we conduct this study to investigate whether financial development is important for real growth in Nepal. We employ a Granger non-causality test developed by Toda and Yamamoto (1995), and analyse the impact of the indicators of financial development (financial depth and private credit) on real growth. Our empirical analysis reveals that financial development causes economic growth significantly. Furthermore, our results show a highly significant impact of trade, gross capital formation and government credit on output growth. Hence, we suggest that economic policy should be aimed at reforming and improving the efficiency of the financial sector, as well as real sector reforms simultaneously to accelerate the economic growth rate of Nepal. Using newly assembled data and hitherto unapplied methodologies, we believe that, this study imparts valuable insight on the role of financial sector development on the economic growth of Nepal.
Vacuum non-linear electrodynamic polarization effects in hard emission of pulsars and magnetars
Creators: name: Denisov, V. I.
name: Sokolov, V. A.
name: Svertilov, S. I.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: The non-linear electrodynamics influence of pulsar magnetic field on the electromagnetic pulse polarization is discussed from the point of observation interpretation. The calculations of pulsar magnetic field impact on electromagnetic pulse polarization are made in such a way to make it easier to interpret these effects in space experiments. The law of hard emission pulse propagation in the pulsar magnetic field according to the vacuum non-linear electrodynamics is obtained. It was shown, that due to the birefringence in the vacuum the front part of any hard emission pulse coming from a pulsar should be linearly polarized and the rest of pulse can have arbitrary polarization. Observational possibilities of vacuum birefringence are discussed. The estimations of detector parameters such as effective area, exposure time and necessity of polarization measurements with high accuracy are given. The combination of large area and extremely long exposure time gives the good opportunity to search the fine polarization effects like vacuum non-linear electrodynamics birefringence.
description: arXiv admin note: text overlap with arXiv:1507.02824 by other authors
การบริหารทรัพยากรมนุษย์เชิงกลยุทธ์ที่ส่งผลต่อความได้เปรียบทางการแข่งขันของธุรกิจโรงแรมขนาดเล็กในประเทศไทย
Creators: name: อรัชมน รัตนวราหะ
name: พิชญ์สินี ตัณฑเสน
name: บุรพร กําบุญ
name: ศิริชญาน์ การะเวก
Publisher: name: สมาคมปรัชญาดุษฎีบัณฑิตทางสังคมศาสตร์ มหาวิทยาลัยรามคำแหง
Year: 2563
Subjects: การบริหารทรัพยากรมนุษย์เชิงกลยุทธ์
การบริหารทรัพยากรมนุษย์
ความได้เปรียบทางการแข่งขัน
Strategic Management
Human Resource Management
Competitive Advantage

description: วารสารดุษฎีบัณฑิตทางสังคมศาสตร์, 10, 2, 406-415
First hard X-ray detection and broad band X-ray study of the unidentified transient AX J1949.8+2534
Creators: name: Sguera, V.
name: Sidoli, L.
name: Paizis, A.
name: Masetti, N.
name: Bird, A. J.
name: Bazzano, A.
Publisher: name: arXiv
Year: 2017
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present the results from INTEGRAL and Swift/XRT observations of the hitherto poorly studied unidentified X-ray transient AX J1949.8+2534, and on archival multiwavelength observations of field objects. Bright hard X-ray outbursts have been discovered above 20 keV for the first time, the measured duty cycle and dynamic range are of the order of 4% and >630, respectively. The source was also detected during a low soft X-ray state (2x10E-12 erg cmE-2 sE-1) thanks to a Swift/XRT followup, which allowed for the first time to perform a soft X-ray spectral analysis as well as significantly improve the source positional uncertainty from arcminute to arcsecond size. From archival near-infrared data, we pinpointed two bright objects as most likely counterparts whose photometric properties are compatible with an early type spectral nature. This strongly supports a High Mass X-ray Binary (HMXB) scenario for AX J1949.8+2534, specifically a Supergiant Fast X-ray Transient (more likely) or alternatively a Be HMXB.
description: Accepted for publication in MNRAS. 8 pages, 6 figures, 4 tables