cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Synthesis and Cation Recognition Study of Novel Benzo Crown Ether Functionalized Enamine Derivatives
Creators: name: Dayanand R. Patil
name: Dattatraya R. Chandam
name: Suryabala D. Jagdale
name: Patil, Prasad P.
name: Madhukar B. Deshmukh
name: Abhijeet G. Mulik
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Engineering
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Science Policy
subject: Cancer
subject: Developmental Biology
subject: Earth and Environmental Sciences
subject: Medicine
subject: Biophysics

description: A novel series of benzo crown ether (dibenzo 18-crown-6 ether, benzo 18-crown-6 ether, and benzo 15-crown-5 ether) functionalized enamines derivatives from amino benzo crown ether (4-amino dibenzo 18-crown-6 ether, 4-amino benzo 18-crown-6 ether, 4-amino benzo 15-crown-5 ether) and substituted 3-(dimethylamino)-1-phenylprop-2-en-1-one compounds have been synthesized. All the synthesized compounds were characterized by infrared, 1H NMR, 13C NMR, distortionless enhancement polarization transfer, and mass and elemental analysis techniques. The cation recognition property for benzo crown ether enamine 8a was studied by absorption and fluorescence spectroscopy.
Exploring universal design with product design students
Creators: name: Bissett-Johnson, Katherine
name: Melles, Gavin
Publisher: name: Swinburne
Year: 2024

description: This paper will review a student project from Swinburne University Industrial Design program, which was focused on Universal Design. Swinburne University offers a 3-year undergraduate program in Industrial Design. We will look at the history, interpretation and the application of a specific set of Universal Design Guidelines as developed by NC State University and via some preliminary text analysis of student submissions investigate if there is any correlation between the application of the guidelines as a part of the design process and the degree that the final outcome appears to be a Universal Design proposal. We will discuss and describe an analysis of the experience of a cohort of students, as determined from a review of text submissions and lecturer review of the design outcome, post the undertaking a product design studio incorporating Universal Design.
The contribution of deprivation and disadvantage to entrepreneurial success
Creators: name: Fisher, Rosemary
name: Langan-Fox, Janice
name: Shepherd, Dean
Publisher: name: Swinburne
Year: 2024

description: This research lends support to the suggestion that successful entrepreneurs experienced deprivation or disadvantage in their childhood or early youth. It is suggested that those childhood experiences are key to the entrepreneur's significant capacity to withstand or not notice aversive and stressful situations, and therefore be willing and able to continue in the face of maladaptive and less adaptive outcomes generated through the entrepreneurship process. Specifically, those experiences of deprivation or disadvantage contribute to entrepreneurial success through the development of resilience. It is suggested that resilience is an enabler of sustained entrepreneurial action, which itself is a precursor to entrepreneurial success.
Complete description of the skull and mandible of the giant mustelid Eomellivora piveteaui Ozansoy, 1965 (Mammalia, Carnivora, Mustelidae), from Batallones (MN10), late Miocene (Madrid, Spain)
Creators: name: Valenciano, Alberto
name: Abella, Juan
name: Sanisidro, Oscar
name: Hartstone-Rose, Adam
name: Álvarez-Sierra, María Ángeles
name: Morales, Jorge
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Science Policy
subject: Biological Sciences
subject: Sociology
subject: FOS: Sociology
subject: Ecology
subject: FOS: Biological sciences
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: Genetics

description: ABSTRACTWe describe cranial, mandibular, and dental remains of five individuals of the giant mustelid Eomellivora piveteaui Ozansoy, 1965, from the late Miocene (MN10) site of Cerro de los Batallones (Madrid, Spain)—the first complete cranial remains recorded for this species and the most complete remains of the genus. This new sample enables a review of the systematic status of Eomellivora, leading us to accept as valid the species E. piveteaui Ozansoy, 1965, E. wimani Zdansky, 1924, E. ursogulo (Orlov, 1948), and E. hungarica Kretzoi, 1942. Our phylogenetic hypothesis indicates that Eomellivora is the sister taxon of the extant Mellivora capensis and E. piveteaui had a common ancestor within the crown group E. wimani–E. ursogulo. Eomellivora piveteaui was specialized for a more hypercarnivorous diet than the largest extant terrestrial mustelids, although it also had some derived bone-crushing adaptations. Eomellivora piveteaui had an active predatory role in the late Miocene carnivore faunas, exploiting both small and relatively large prey.SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP
A REVIEW ON FLEXIBILITY IN ARCHITECTURAL DESIGN
Creators: name: Hanieh FarokhiFirouzi
Publisher: name: TuEngr Group
Year: 2019
Subjects: Architecture with Flexibility
Ambiguities in flexible design
Flexibility of the Criteria of the User
Flexible Creator of the Architect.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 6, 779-786
IMPACT OF THE MAP TA PHUT INDUSTRIAL ESTATE ON COASTAL ENVIRONMENTAL CHANGES AND TREND ANALYSIS
Creators: name: Krittanat Ratanachai, Petchporn Chawakitchareon
Publisher: name: TuEngr Group
Year: 2019
Subjects: Contour map
Sediment quality
Water quality
Coastal seawater monitoring
Marine ecology changes
Seawater heavy metals observation.

description: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 10, 6, 787-796
Facile Synthesis of 2-(4-Hydroxybiphenyl-3-yl)-1H-indoles from Anilines and 5′-Bromo-2′-hydroxyacetophenone
Creators: name: Subedi, Milan
name: Jianbo Chen
name: Eunsol Kang
name: Kim, Kyung Im
name: Youngjoo Byun
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Chemistry
subject: Biotechnology
subject: Neuroscience
subject: Molecular Biology
subject: Cell Biology
subject: Microbiology
subject: Medicine
subject: Biochemistry
subject: Biophysics

description: 2-Arylindoles are attractive scaffolds because they are found in many pharmacologically active molecules. In this study, we describe the facile synthesis of diverse 2-(2-hydroxyphenyl)-1H-indoles from anilines and 5′-bromo-2′-hydroxyacetophenone in two steps using palladium-catalyzed indole cyclization as a key reaction. The indole cyclization was primarily controlled by the substituent properties of anilines. Suzuki-coupling reactions of 2-(5′-bromo-2′-hydroxyphenyl)-1H-indoles with arylboronic acids provided the corresponding 2-(4-hydroxybiphenyl-3-yl)-1H-indoles in moderate yield.
An exploratory study investigating the dimensions influencing consumersâ¿¿ purchase intentions relating to organic food in urban China
Creators: name: Chen, Jue
name: Lobo, Antonio
Publisher: name: Swinburne
Year: 2024

description: This study aims at investigating the dimensions and their components which influence consumers’ attitudes, pre-purchase evaluation and behavioural intentions relating to the purchase of organic food products in urban China. Data was collected through randomly distributed self-administered questionnaires at major supermarkets in Beijing and Shanghai. The findings of this study revealed that Chinese consumers’ attitudes are influenced by the following dimensions and components: product-related (sensory appeal and value for money), regulatory, ethnocentrism and partially by lifestyle (especially self indulgence). Additionally it was revealed by a process of hierarchical multiple regression that the above mentioned dimensions and components partially impacted on consumers’ behavioural intentions through the mediating effects of both their attitudes and pre-purchase evaluation.
Synthesis and Cation Recognition Study of Novel Benzo Crown Ether Functionalized Enamine Derivatives
Creators: name: Dayanand R. Patil
name: Dattatraya R. Chandam
name: Suryabala D. Jagdale
name: Patil, Prasad P.
name: Madhukar B. Deshmukh
name: Abhijeet G. Mulik
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Engineering
subject: 60506 Virology
subject: FOS: Biological sciences
subject: Science Policy
subject: Cancer
subject: Developmental Biology
subject: Earth and Environmental Sciences
subject: Medicine
subject: Biophysics

description: A novel series of benzo crown ether (dibenzo 18-crown-6 ether, benzo 18-crown-6 ether and benzo 15-crown-5 ether) functionalized enamines derivatives from amino benzo crown ether (4-amino dibenzo 18-crown-6 ether, 4-amino benzo 18-crown-6 ether, 4-amino benzo 15-crown-5 ether) and substituted 3-(dimethylamino)-1-phenylprop-2-en-1-one compounds have been synthesized. All the synthesized compounds were characterized by IR, 1H NMR, 13C NMR, DEPT 135, Mass and Elemental analysis techniques. The cation recognition property for benzo crown ether enamine 8a was studied by absorption and fluorescence spectroscopy.
The role of Honours in promoting research literate graduates for, and with, industry
Creators: name: Barron, Deirdre
name: Zeegers, Margaret
name: Jackson, Simon
name: Barnes, Carolyn
name: Taffe, Simone
Publisher: name: Swinburne
Year: 2024

description: The paper reports on a program that brings together what is known about active learning in design education, that is, learning by doing, and what is known about communities of practice to address a real concern - the lack of take up of Higher Degree by Research programs within in the discipline of design. The report Building Australia's Research Capacity Report (2008) highlights this problem, stating '...it is evident that postgraduate research is in direct competition with the workforce, particularly at the graduate and entry levels, in the current climate of low professional unemployment' (p.87). To meet such calls, Australian Universities have focused on increasing the completion rates of existing Higher Degree by Research candidates. This paper focuses on the role of honours programs as servig two purposes: first to increase the numbers of undergraduate students taking up Higher Degree by Research programs as a way of increasing the numbers of doctoral qualified workers, and second, to produce research literate honours graduates for industry. At the same time literature around research training identifies the vagaries associated with research (Barron & Zeegers, 2002) as one of the barriers faced by Higher Degree by Research students in their research training. This paper looks to understandings generated through communities of practice and Legitimate Peripheral Participation to argue for a model of honours and Higher Degree by Research training that address such vagaries. The model uses collaboration and working with industry and researchers to establish Active Learning experiences - participants with various levels of research expertise working alongside each other in research clusters on industry projects to experience how methods are employed and problems are addresses and solved. The model argues for a staged, deliberate process of drawing newcomers into a given professional field, where they work with increasing more experienced practitioners as a part of specific communities of practice until they themselves become proficient.
Biocidal Nano-Silver Reinforced Activated Charcoal in Water Treatment
Creators: name: V. Sherly Arputha Kiruba
name: P. Mosae Selvakumar
name: Dakshinamurthy, Arun
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Plant Biology
subject: FOS: Biological sciences
subject: Science Policy
subject: Biological Sciences
subject: Meta Science
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Molecular Biology
subject: Biochemistry

description: Improvements in nanotechnology make eco-friendly and cost-effective solutions to the drinking water contamination problem feasible. Activated charcoal, which is widely used for water purification, can be more effectively employed when reinforced with nanoparticles. For antimicrobial water treatment activated charcoal can be reinforced with silver nanoparticles (SNPs) for best results. Among various methods for the synthesis of nanoparticles, green synthesis mediated by phytoconstituents is preferable, as it is both cost-effective and environmentally friendly. Here we report a green method for synthesizing SNPs from musk melon fruit extract and activated charcoal from coconut shells. The prepared activated charcoal was reinforced with the green-synthesized SNPs and used in microbial water filtration. The efficiency of nanosilver reinforced activated charcoal was higher than virgin activated charcoal proving improved filtration against microbes after successful reinforcement.
VASA: an exploratory visualization tool for mapping spatio-temporal structure of mobility – a COVID-19 case study
Creators: name: Noi, E.
name: Rudolph, A.
name: Dodge, S.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Medicine
subject: Neuroscience
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: Exploratory data analysis tools designed to measure global and local spatial autocorrelation (e.g. Moran’s I statistic) have become standard in modern GIS software. However, there has been little development in amending these tools for visualization and analysis of patterns captured in spatio-temporal data. We design and implement an exploratory mapping tool, VASA (Visual Analysis for Spatial Association), that streamlines analytical pipelines in assessing spatio-temporal structure of data and enables enhanced visual display of the patterns captured in data. Specifically, VASA applies a set of cartographic visual variables to map local measures of spatial autocorrelation and helps delineate micro and macro trends in space-time processes. Two visual displays are presented: recency and consistency map and line-scatter plots. The former combines spatial and temporal data view of local clusters, while the latter drills down on the temporal trends of the phenomena. As a case study, we demonstrate the usability of VASA for the investigation of mobility patterns in response to the COVID-19 pandemic throughout 2020 in the United States. Using daily county-level and grid-level mobility metrics obtained from three different sources (SafeGraph, Cuebiq, and Mapbox), we demonstrate cartographic functionality of VASA for a swift exploratory analysis and comparison of mobility trends at different regional scales.
Epistemological positions in design research: a brief review of the literature
Creators: name: Feast, Luke
name: Melles, Gavin
Publisher: name: Swinburne
Year: 2024

description: Design research is not simply concerned with speculations regarding the relationship of theory and practice. Design research also brings out significant questions regarding the nature of research and the position occupied by the doctorate in university education. This paper reviews the major epistemological positions informing theories of design research. Analyses of examples from subjectivist, constructivist and objectivist epistemologies are presented. The paper concludes by considering the pedagogical implications of the role of disciplinarity in discourses of design research. The paper does not aim to seek statistical generalization but rather to explore the complexity of the issue.
The new very-high-resolution coupled global configuration for EC-Earth 4
Creators: name: Castrillo, Miguel
name: Acosta, Mario
name: Arsouze, Thomas
name: Aya, Iria
name: Lapin, Vladimir
name: Montané, Gilbert
name: Palomas, Sergi
name: Paronuzzi-Ticco, Stella
name: Serradell, Kim
name: Tintó, Oriol
name: Yepes, Xavier
name: Bricaud, Clément
Publisher: name: Zenodo
Year: 2022
Subjects: HPC
EC-Earth
High resolution
Very-high resolution
scalability
climate models
ESiWACE
PRACE
performance
NEMO
IMMERSE

description: Recent studies have established that the typical atmospheric and oceanic resolutions used
 for the CMIP5 coordinated exercise, i.e., around 40km-150km globally, are limiting factors to
 correctly reproduce the climate mean state and variability. In the framework of the ESiWACE
 project, the Barcelona Supercomputing Center (BSC) developed a coupled version of the
 EC-Earth 3 climate model at a groundbreaking horizontal resolution of about 15km in each
 climate system component. In the atmosphere, the horizontal domain was based on a
 spectral truncation of the atmospheric model (IFS) at T1279 (15 km) together with 91 vertical
 levels. The ocean component (NEMO) ran on the ORCA12 tripolar (cartesian) grid at a
 horizontal resolution of about 1/12° (16 km), with 75 vertical levels.
 This very-high-resolution (VHR) configuration was used in the Glob15km project to run a
 50-year spinup from which one historical and one control simulation of 50 years each were
 started, following the HighResMIP protocol from CMIP6. These experiments are currently
 being used to identify the improvements in process representation with respect to coarser
 resolution and to pin down physical and dynamical reasons behind these differences
 induced by resolution change.
 The VHR coupled configuration was a great benchmark to reveal the most critical scalability
 problems of the EC-Earth 3 model. Within the ESiWACE2 project, those issues have been
 tackled to allow operational climate predictions at more than 1 SYPD (Simulated Years Per
 Day) with production-mode configurations. The new Tco639-ORCA12 configuration is based
 on the community EC-Earth 4 model, made up of OpenIFS cycle 43r3 and NEMO 4, and
 uses a cubic octahedral grid in the atmosphere. In this version of EC-Earth, both the
 atmospheric and the oceanic component output diagnostics through the asynchronous XIOS
 servers, contributing to reducing the I/O overhead and improving scalability, which will be
 evaluated at the end on one of the forthcoming pre-exascale EuroHPC systems.
 This new configuration has already been scaled in MareNostrum 4 with a peak performance
 of 2 SYPD. It will be subject to the last phase of development and optimization until it is
 finally deployed in one of the forthcoming Pre-Exascale platforms to facilitate the execution
 of experiments with an unprecedented time-to-solution and allowing additional output
 capabilities to help understand the climate mean state, variability, and extremes.
Consumer Risk Assessment Associated with Intake of Pesticide Residues in Food of Plant Origin from the Retail Market in Poland
Creators: name: Paweł Struciński
name: Bożena Morzycka
name: Góralczyk, Katarzyna
name: Hernik, Agnieszka
name: Czaja, Katarzyna
name: Korcz, Wojciech
name: Małgorzata Matuszak
name: Minorczyk, Maria
name: Łyczewska, Monika
name: Pruss, Barbara
name: Ludwicki, Jan K.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: Information and Computing Sciences
Biological Sciences
Earth and Environmental Sciences
Biotechnology

description: ABSTRACTThe aim of this study was to characterize short- and long-term risk for consumers associated with dietary intake of pesticide residues in fruits, vegetables, and other foodstuffs available on the Polish market based on 2010–2013 official surveillance results. Among 779 samples collected from 2010 to 2013 no pesticide residue was found in 39.7% samples while 58.5% contained residues at or below the EU Maximum Residue Levels (MRLs). Non-compliances (residues above the respective MRLs) were found in 14 samples (1.8%). Most of the estimated daily intakes were well below 1% of respective acceptable daily intake (ADI) values. The highest intake for children and adults was about 7% and 1.5% of ADI, respectively. For non-compliant results acute risk was characterized. Predicted short-term intakes for children and adults ranged from 0.7% to 425%, and from 0.2% to 100% of respective acute reference dose, respectively. Results of chronic risk characterization show that consumers in Poland are adequately protected; however, incidental cases where residue levels may potentially pose a threat to consumers’ health due to acute exposure cannot be excluded.
DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion
Creators: name: Kotula, Ewa
name: Berthault, Nathalie
name: Celine Agrario
name: Marie-Christine Lienafa
name: Simon, Anthony
name: Dingli, Florent
name: Damarys Loew
name: Vonick Sibut
name: Saule, Simon
name: Dutreix, Marie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Cancer
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biochemistry

description: ABSTRACTThe DNA-dependent protein kinase catalytic subunit (DNA-PKcs) plays a major role in DNA damage signaling and repair and is also frequently overexpressed in tumor metastasis. We used isogenic cell lines expressing different levels of DNA-PKcs to investigate the role of DNA-PKcs in metastatic development. We found that DNA-PKcs participates in melanoma primary tumor and metastasis development by stimulating angiogenesis, migration and invasion. Comparison of conditioned medium content from DNA-PKcs-proficient and deficient cells reveals that DNA-PKcs controls secretion of at least 103 proteins (including 44 metastasis-associated with FBLN1, SERPINA3, MMP8, HSPG2 and the inhibitors of matrix metalloproteinases, such as α-2M and TIMP-2). High throughput analysis of secretomes, proteomes and transcriptomes, indicate that DNA-PKcs regulates the secretion of 85 proteins without affecting their gene expression. Our data demonstrate that DNA-PKcs has a pro-metastatic activity via the modification of the tumor microenvironment. This study shows for the first time a direct link between DNA damage repair and cancer metastasis and highlights the importance of DNA-PKcs as a potential target for anti-metastatic treatment.
A novel role for the condensin II complex in cellular senescence
Creators: name: Yuhki Yokoyama
name: Hengrui Zhu
name: Rugang Zhang
name: Ken-Ichi Noma
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Cancer
subject: Hematology

description: Although cellular senescence is accompanied by global alterations in genome architecture, how the genome is restructured during the senescent processes is not well understood. Here, we show that the hCAP-H2 subunit of the condensin II complex exists as either a full-length protein or an N-terminus truncated variant (ΔN). While the full-length hCAP-H2 associates with mitotic chromosomes, the ΔN variant exists as an insoluble nuclear structure. When overexpressed, both hCAP-H2 isoforms assemble this nuclear architecture and induce senescence-associated heterochromatic foci (SAHF). The hCAP-H2ΔN protein accumulates as cells approach senescence, and hCAP-H2 knockdown inhibits oncogene-induced senescence. This study identifies a novel mechanism whereby condensin drives senescence via nuclear/genomic reorganization.
A novel role for the condensin II complex in cellular senescence
Creators: name: Yuhki Yokoyama
name: Hengrui Zhu
name: Rugang Zhang
name: Ken-Ichi Noma
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Hematology
subject: Cancer
subject: Biological Sciences
subject: Earth and Environmental Sciences
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Genetics
subject: Cell Biology
subject: Microbiology
subject: Biochemistry

description: Although cellular senescence is accompanied by global alterations in genome architecture, how the genome is restructured during the senescent processes is not well understood. Here, we show that the hCAP-H2 subunit of the condensin II complex exists as either a full-length protein or an N-terminus truncated variant (ΔN). While the full-length hCAP-H2 associates with mitotic chromosomes, the ΔN variant exists as an insoluble nuclear structure. When overexpressed, both hCAP-H2 isoforms assemble this nuclear architecture and induce senescence-associated heterochromatic foci (SAHF). The hCAP-H2ΔN protein accumulates as cells approach senescence, and hCAP-H2 knockdown inhibits oncogene-induced senescence. This study identifies a novel mechanism whereby condensin drives senescence via nuclear/genomic reorganization.
DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion
Creators: name: Kotula, Ewa
name: Berthault, Nathalie
name: Celine Agrario
name: Marie-Christine Lienafa
name: Simon, Anthony
name: Dingli, Florent
name: Damarys Loew
name: Vonick Sibut
name: Saule, Simon
name: Dutreix, Marie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Cancer
subject: Developmental Biology
subject: Mathematics
subject: FOS: Mathematics
subject: Biological Sciences
subject: Molecular Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biochemistry

description: The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) plays a major role in DNA damage signaling and repair and is also frequently overexpressed in tumor metastasis. We used isogenic cell lines expressing different levels of DNA-PKcs to investigate the role of DNA-PKcs in metastatic development. We found that DNA-PKcs participates in melanoma primary tumor and metastasis development by stimulating angiogenesis, migration and invasion. Comparison of conditioned medium content from DNA-PKcs-proficient and deficient cells reveals that DNA-PKcs controls secretion of at least 103 proteins (including 44 metastasis-associated with FBLN1, SERPINA3, MMP-8, HSPG2 and the inhibitors of matrix metalloproteinases, such as α-2M and TIMP-2). High throughput analysis of secretomes, proteomes and transcriptomes, indicate that DNA-PKcs regulates the secretion of 85 proteins without affecting their gene expression. Our data demonstrate that DNA-PKcs has a pro-metastatic activity via the modification of the tumor microenvironment. This study shows for the first time a direct link between DNA damage repair and cancer metastasis and highlights the importance of DNA-PKcs as a potential target for anti-metastatic treatment.
Women in family businesses: perception and understanding of entrepreneurship
Creators: name: Hougaz, Laura
name: Betta, Michela
Publisher: name: Swinburne
Year: 2024

description: This paper will make a significant contribution to the discussion on entrepreneurship in family business by examining the dynamic role that women play in the family firm, and by analysing their perspective of their own entrepreneurial contribution to the success of the business. It will also contribute to the issue of business family dynamics, in particular the interrelation between the two closely linked domains, the business and the family, and to the gender issues in family business, which to date continue to remain relatively under-researched.
Ontological approach for e-services
Creators: name: Li, Li
name: Yang, Yun
Publisher: name: Swinburne
Year: 2024

description: Information sharing is crucial to the success of business applications in a collaborative environment. This paper presents a novel approach for information sharing which is suitable for distributed computing. Agent technologies are applied to cope with service agents' on and off and to provide semantic support for implementation of complex ebusiness applications that may span diverse organisations. A finite state machine (FSM), which is ideally suited for modelling business processes, is investigated to facilitate process automation. Our approach aims to support dynamic information sharing and reuse in e-business applications. A case study illustrates our ontological approach in employing FSM agents in an inter-organisational environment. A demonstration integrating the JADE platform andframe-based ontologies is also presented.
Molecular characterization of salt stress in grapevine cultivars (Vitis vinifera L.) and rootstocks
Creators: name: Ağaoğlu, Y. S.
name: Ergül, A.
name: Aras, S.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Salt stress is an important factor inducing the expression of many genes; e.g. the osmotin gene is one of the very important genes responding to NaCl stress. After exposure to NaCl stress, the osmotin gene expression level was investigated in 6 grape cultivars grown in GAP (Southeast Anatolian region including the provinces Gaziantep, Şanliurfa, Diyarbakır, Mardin, Batman, Siirt and Şırnak) and in 4 grape cultivars and 7 rootstocks recommended to the GAP region. Expression levels were investigated by Northern blot analysis. The osmotin expression level was higher in scion cultivars than in rootstocks. Within grapevine cultivars, the highest osmotin gene expression level was observed in cv. Tahannebi, followed by Hönüsü, another GAP region cultivar. The osmotin gene expression levels of two grape cultivars, Ata sarisi and Alphonse Lavallée recommended to the GAP region, were lower than those of Hönüsü. On the other hand the GAP region cultivars Ağ Besni, Rumi, Kabarcık, Dımıþkı and the recommended cultivars Razakı and Italia were significantly different in their expression levels. Among rootstocks 1616 C displayed the highest expression level, followed by 99R; they were followed by 1613C. In 110R the expression level was slightly lower than in the above mentioned ones and 41B. In SO4 and 5C the level of expression remained at the control level.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 3 (2004): Vitis
Old dogs, new tricks? Online dating and older adults
Creators: name: Malta, Sue
name: Farquharson, Karen
Publisher: name: Swinburne
Year: 2024

description: This paper reports the findings of semi-structured qualitative interviews with 30 older adults (aged 60 – 76 years), all of whom used online dating websites to find new romantic partnerships. The interviews were conducted using four different interview methods: (1) face-to-face and (2) telephone interviews and (3) email and (4) instant messaging, and have been described previously (see Malta 2009). Most studies of online romantic relationships use younger sample populations making it difficult to generalize to older adults (see for instance, Donn and Sherman 2002) and are usually situated within the psychological literature (for example, Whitty and Gavin 2001). This study describes the phenomenon amongst seniors and positions it within a sociological framework. We chart the progression of older adult romantic relationships, describing the participants’ reasons and motivations for going online to look for romantic partners, followed by the way these romances unfold and how the online environment structures their development through various predetermined stages: the posting of personal profiles, the initial contact ('kisses' and 'winks'), emails, phone contact, face-to-face meeting, and finally sex. The majority of these online-initiated relationships followed this very structured pattern of progression, with only minor variations. We argue that online dating affords older adults the opportunity to shop around for their perfect match – discarding those who do not suit – simply because of the large number of possible partners available online; a possibility not available through offline means. We further argue that using an online dating website provides a particular structure that fosters the development of a new romance and causes it to unfold through a standardized process that is difficult to circumvent.
Transpiration of grapevines and co-habitating cover crop and weed species in a vineyard. A “snapshot” at diurnal trends
Creators: name: Lopes, C.
name: Monteiro, A.
name: Rückert, F. E.
name: Gruber, B.
name: Steinberg, B.
name: Schultz, H. R.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: The objective of this study was to quantify transpiration rates of two cover crops, Festuca rubra subsp. rubra (red fescue) and Medicago lupulina (black medick) and 4 weeds, Chenopodium album (fat hen), Cirsium arvense (creeping thistle), Malva neglecta (common mallow) and Taraxacum officinale (dandelion) occurring in a mixed stand in a commercial steep-slope, North-South oriented vineyard as compared to vines, cv. Riesling near Johannisberg (Rheingau), Germany. Leaf transpiration (E) was measured directly on the cover crop and weed species with a portable gas exchange measurement system. Grapevine transpiration was measured concomitantly using custommade Granier-type xylem sap flow gauges. Measurements were conducted on two days in August (15th and 22nd) in 2001 under hot and sunny conditions. All herbaceous species presented a similar diurnal pattern of E, with low values in the morning and afternoon and peak values between 12 and 15 h. In contrast E of grapevines peaked mid-morning (between 8 and 10 h) remained relatively stable until mid-afternoon (16 h) before decreasing continuously until darkness. Significant differences in E between the herbaceous species were observed throughout the day. In general transpiration rates were highest for M. neglecta and lowest for C. arvense, T. officinale and F. rubra subsp. rubra. We estimated the projected leaf area indices (leaf area per surface area covered) for each species and calculated possible transpiration rates for pure stands assuming that all leaves were well exposed. Potential transpiration rates ranged from about 1 mm d-1 (one l m-2 of soil surface) for F. rubra subsp. rubra to = 5 mm d-1 for M. neglecta as compared to only 0.9 mm d-1 for grapevine. These results underline the importance of appropriate cover crop species and the control of some weed species with respect to water use.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 3 (2004): Vitis
DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion
Creators: name: Kotula, Ewa
name: Berthault, Nathalie
name: Celine Agrario
name: Marie-Christine Lienafa
name: Simon, Anthony
name: Dingli, Florent
name: Damarys Loew
name: Vonick Sibut
name: Saule, Simon
name: Dutreix, Marie
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer

description: The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) plays a major role in DNA damage signaling and repair and is also frequently overexpressed in tumor metastasis. We used isogenic cell lines expressing different levels of DNA-PKcs to investigate the role of DNA-PKcs in metastatic development. We found that DNA-PKcs participates in melanoma primary tumor and metastasis development by stimulating angiogenesis, migration and invasion. Comparison of conditioned medium content from DNA-PKcs-proficient and deficient cells reveals that DNA-PKcs controls secretion of at least 103 proteins (including 44 metastasis-associated with FBLN1, SERPINA3, MMP-8, HSPG2 and the inhibitors of matrix metalloproteinases, such as α-2M and TIMP-2). High throughput analysis of secretomes, proteomes and transcriptomes, indicate that DNA-PKcs regulates the secretion of 85 proteins without affecting their gene expression. Our data demonstrate that DNA-PKcs has a pro-metastatic activity via the modification of the tumor microenvironment. This study shows for the first time a direct link between DNA damage repair and cancer metastasis and highlights the importance of DNA-PKcs as a potential target for anti-metastatic treatment.
To blend or not to blend? Synchronous and asynchronous teaching perspectives in online marketing education
Creators: name: Greenland, Steven
name: Ho, Henry
Publisher: name: Swinburne
Year: 2024

description: With the rapid expansion in online marketing education it is important that optimum teaching delivery methods are used. Ongoing debate surrounds the use of live chats versus discussion threads for online activities. This paper focuses on both these synchronous and asynchronous online tutorial delivery formats from both student and staff, as well as the online learning management system perspectives. Different interactive student behaviour within the unit’s learning site is observed depending on the tutorial delivery format used. Clear preferences, advantages and limitations are observed amongst both staff and students. Implications for the delivery of online marketing units are discussed.
Genotype assessment of grape regenerants from floral explants
Creators: name: Martinelli, L.
name: Zambanini, J.
name: Grando, M. S.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: A molecular typing of regenerant vines based on co-dominant simple sequence repeat (SSR) markers was applied for checking recombination events during somatic embryogenesis from floral explants. Twenty-one samples of somatic embryos and plantlets from embryogenic callus of both anthers and ovaries of the V. vinifera cv. Chardonnay, the rootstock Kober 125 AA, and the accession V. rupestris du Lot were randomly chosen from a number of regenerant lines. The genotype at polymorphic VVS2, VVMD5, VVMD7, VVMD27, VrZAG62 and VrZAG79 loci was produced and compared with reference patterns. No recombination events were detected in the cells involved in the somatic embryogenesis induction of all the checked samples, since all of them generated the same SSR profile of the grape variety from which explants were isolated.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 3 (2004): Vitis
Aporte al conocimiento del genero Cycloneda Crotch (Coleoptera: Coccinellidae): nuevas especies del Peru
Creators: name: Navarrete, Abdhiel Arnaldo Bustamante
name: Loayza, Walter Guillermo Cosio
name: Anahi Jeannette, Oroz Ramos
Publisher: name: figshare
Year: 2020
Subjects: subject: Zoology
subject: FOS: Biological sciences

description: Se describen dos nuevas especies del género Cycloneda Crotch 1871: Cycloneda andresi n. sp., proveniente de las regiones de Ancash, Ayacucho y Cusco, en las sierras del centro y sur del Perú, y Cycloneda marcapatae n. sp., originaria de la selva alta del Cusco.Two new species of Cycloneda Crotch 1871 are described: Cycloneda andresi n. sp. comes from the Ancash, Ayacucho and Cusco regions, in the central and southern highlands of Peru, and Cycloneda marcapatae n.sp. originates in the high forest of Cusco.
Genetic variability and incidence of systemic diseases in wild vines (Vitis vinifera ssp. silvestris) along the Danube
Creators: name: Regner, F.
name: Hack, R.
name: Gangl, H.
name: Leitner, G.
name: Mandl, K.
name: Tiefenbrunner, W.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: In the riparian woods of Danube and March east of Vienna 87 wild specimens of Vitis vinifera ssp. silvestris were genetically analysed and compared. The silvestris population can be split into 6 distinct groups, but this clustering cannot be explained solely by the geographical distance. The unique genetic variability observed represents a strong case for preservation of wild grapevines. The incidence of bacterioses, viroses and nematodes transmitting nepoviruses to these vines were registered. None of the analysed specimens suffered from Agrobacterium vitis-induced crown gall. Only some vines were infected by viral pathogens such as GLRaV I and SLRV. Thus the wild vines do not constitute a risk for the surrounding commercial vineyards. On the other hand, diseases spread from cultivated grapevines may seriously harm the wild vine population. Four species of nematodes transmitting nepoviruses were registered. Samples of Xiphinema vuittenezi and Longidorus attenuatus from the Lobau (natural forests, north of the Danube in the area of Vienna) differ morphometrically from others found on arable soils or isolated from the research area.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 3 (2004): Vitis
Vergleichende Untersuchung der bodenbewohnenden Nematodenfauna von mit der Wurzelreblaus (Viteus vitifoliae Fitch) befallenen Weinreben (Vitis spp.)
Creators: name: Hoschitz, M.
name: Reisenzein, H.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Comparative study ofthe soil-living nematofauna associated with vine (Vitis spp.) infested with phylloxera (Viteus vitifoliae Fitch) The diversity and the community structure of nematodes, and the correlation between the occurrence of nematodes and the infestation of grapevines (Vitis spp.) with grape phylloxera (Viteus vitifoliae) were studied. Grapevines ungrafted and grafted to different rootstocks were planted and samples of roots and soil were collected at 7 sites in the Austrian vine growing regions Weinviertel, Neusiedlersee, Südburgenland, and Südoststeiermark. The formation of nodosities on rootlets and the nematode fauna were examined. A total of 58 nematode genera (37 families) were found to be associated with grapevines. Mean nematode abundance in the 7 vineyards ranged from 342 to 444 individuals per 100 g soil. Diversity indices, mean evenness, Maturity Index (MI), and Plant Parasite Index (PPI) were nearly identical among sites and no significant differences were found between phylloxera-infested and non-infested rootstocks. Looking at the trophic structure given by feeding types (bacteriovores, carnivores, omnivores, plant parasites, fungivores) the plant parasitic nematodes were the dominant feeding group; they were detected in all vineyards. Helicotylenchus digonicus, Helicotylenchus vulgaris, Paratylenchus spp., Pratylenchus spp., Mesocriconema xenoplax, Tylenchorhynchus dubius and Xiphinema vuittenezi were the most frequent plant parasitic nematodes. Helicotylenchus was the only nematode genera correlated with phylloxera infestation. The genera Helicotylenchus showed significantly higher abundances at rootstocks infested with phylloxera and at some sites its abundance was up to 680 individuals per 100 g soil.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 3 (2004): Vitis
Research experience as professional learning and a change agent for design: two examples of undergraduate participation in design research projects
Creators: name: Barnes, Carolyn
name: Taffe, Simone
name: Barron, Deirdre
name: Jackson, Simon
name: Zeegers, Margaret
Publisher: name: Swinburne
Year: 2024

description: This paper considers the imperatives of professional learning and research experience in design education. It reports on two research projects that included Honours students in the investigation team. Providing undergraduate students with research experience is seen as intrinsic to the pedagogical success and socio-economic value of university education. Including professional learning, where undergraduate students work in an industry context or on real-world projects, is thought to make learning more relevant and better prepare students for work. Offering Honours design students research experience as a special form of professional learning has potential benefits for graphic design. Knowledge in a vocational field like graphic design is mostly practice-driven, graphic design's status diminished by designers' lack of access to systematically produced evidence and exemplars of effective practice. The projects discussed in this paper investigated the use of participatory processes in graphic design. Today, co-creative practices and audiencecreated content are seen as important drivers of economic activity and cultural innovation, but participatory design is rarely used in graphic design since project budgets and time frames allow little scope for rigorous audience research. The nature of participatory design also challenges graphic designers' professional identity as creative and communication experts. Our paper reviews general arguments for the inclusion of professional learning and research experience in undergraduate education, considering their implications for design. The paper's discussion section builds on our findings and relevant literature to present research experience in design education as a potential change agent in graphic design.
Water-stress induced physiological changes in leaves of four container-grown grapevine cultivars (Vitis vinifera L.)
Creators: name: Gómez-Del-Campo, M.
name: Baeza, P.
name: Ruiz, C.
name: Lissarrague, J. R.
Publisher: name: VITIS - Journal of Grapevine Research
Year: 2015

description: Predawn leaf water potential, night respiration, stomatal conductance, transpiration, and photosynthesis of 4 grapevine cultivars were assessed under irrigated and non-irrigated conditions in July, August and September 1994. Predawn leaf water potential was not significantly related to either stomatal conductance or photosynthesis. Water stress induced distinct stomatal closure in all cultivars at 11 a.m. For a given stomatal conductance rate, photosynthesis of stressed vines was lower than that of nonstressed vines. At similar stomatal conductance rate, photosynthesis was lower in cv. Chardonnay than in any other cultivar. Photosynthesis was the physiological parameter mostly affected by water stress. Dry matter production was linearly related to stomatal conductance, photosynthesis, and the night respiration to photosynthesis ratio for all vines pooled together. In contrast, under stress conditions dry matter production was not related to any physiological parameter.
description: VITIS - Journal of Grapevine Research, Vol. 43 No. 3 (2004): Vitis
COVID-19: Strategies for Engaging Remote Learners in Medical Education
Creators: name: Zayabalaradjane Zayapragassarazan
Publisher: name: F1000 Research Limited
Year: 2020

description: This document is the Version 2 of:
Zayapragassarazan Z. COVID-19: Strategies for Online Engagement of Remote Learners [version 1; not peer reviewed]. F1000Research 2020, 9:246 (document) (https://doi.org/10.7490/f1000research.1117835.1)

This document discusses about the different strategies for ensuring higher levels of online student engagement in medical education in the wake of COVID-19.