cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Lasioglossum (Habralictellus) adriani Genaro 2001
Creators: name: Duarte, Sandra
name: Breto, Dayron
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Halictidae
Lasioglossum
Lasioglossum adriani

description: Lasioglossum (Habralictellus) adriani Genaro
(Figs. 31–33)
Lasioglossum (Dialictus) adriani Genaro, 2001b. Solenodon 1: 38–44 [39] *
Type material examined: Holotype 1♀ (18.4526), Cuba, Pinar del Río, Sierra de Guane, Sierra de Gabino, 2000- 08, leg. A. González.
Original label data: CUBA Sierra de / Gabino, Sierra / Guane, Pinar / del Río, VIII.00 / col. A. Gonzalez [handwritten] // HOLOTYPUS / Lasioglossum ♀ / (Dialictus) / adriani Genaro [red label, handwritten] // 18.4526 [printed].
Allotype 1♂ (18.6745), Cuba, Sierra de los Órganos, Rancho Mundito, 1947-07-4, leg. J. Ferrás.
Remarks: 1 paratype is deposited in UKNHM collection.
description: Published as part of Duarte, Sandra & Breto, Dayron, 2024, Type catalogue of Hymenoptera (Insecta) housed in the Museo Nacional de Historia Natural de Cuba, pp. 301-336 in Zootaxa 5523 (3) on page 317, DOI: 10.11646/zootaxa.5523.3.1, http://zenodo.org/record/13949447
BRIBERY, CORRUPTION, AND COMPLIANCE: STRENGTHENING ANTI-FINANCIAL CRIME STRATEGIES IN NIGERIA'S FINANCIAL SYSTEM
Creators: name: Tayo, Yussuf
name: Felicia, Oluremilekun Oladeji
name: Quadri, Adebayo Lawal
Publisher: name: SADI JOURNALS
Year: 2025
Subjects: Anti-Financial Crime, Bribery & Corruption and Financial System.

description: The study successfully examined the effectiveness of anti-corruption compliance measures in Nigeria, evaluated the role of anti-bribery frameworks, and assessed enforcement mechanisms to provide actionable strategies for strengthening compliance and reducing financial crimes in the country. Using a cross-sectional design, the study focused on professionals in Nigeria’s financial institutions, regulatory bodies, and government sectors. A sample of 150 respondents was selected through stratified random sampling. Data were collected using structured questionnaires and analyzed with SPSS for descriptive and inferential insights. The findings showed that compliance components, including regulatory oversight, internal controls, and policy enforcement, significantly influenced anti-corruption efforts. Policy enforcement was the strongest predictor (t = 7.892, p < 0.05), followed by regulatory oversight (t = 5.297, p < 0.05) and internal controls (t = 4.647, p < 0.05). Together, these variables explained 65.9% (R² = 0.659) of the variations in bribery and corruption, with the model being highly significant (F = 78.84, p < 0.05). The study concluded that a holistic and transparent compliance strategy is essential for reducing bribery and corruption in Nigeria’s financial system
Predictive factors in OCT analysis for visual outcome in exudative AMD
Creators: name: Gamulescu, Maria-Andreea
name: Panagakis, Georgios
name: Theek, Carmen
name: Helbig, Horst
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: OPTICAL COHERENCE TOMOGRAPHY; DIABETIC MACULAR EDEMA; TRIAMCINOLONE ACETONIDE; RESOLUTION; INTEGRITY; INJECTION; ACUITY;
subject: 610 Medizin

description: Background. Reliable predictive factors for therapy outcome may enable treating physicians to counsel their patients more efficiently concerning probability of improvement or time point of discontinuation of a certain therapy. Methods. This is a retrospective analysis of 87 patients with exudative age-related macular degeneration who received three monthly intravitreal ranibizumab injections. Visual acuity before initiation of intravitreal therapy and 4-6 weeks after last intravitreal injection was compared and related to the preoperative visualisation of continuity of the outer retinal layers as assessed by OCT: external limiting membrane (ELM), inner photoreceptor segments (IPS), junction between inner and outer segments (IS/OS), and outer photoreceptor segments (OPS). Results. Visual acuity increased in 40 of 87 (46.0%) patients, it remained stable in 25 (28.7%), and 22 (25.3%) patients had decreased visual acuity four to six weeks after triple intravitreal ranibizumab injections. No statistically significant predictive value could be demonstrated for grade of continuity of outer retinal layers concerning visual acuity development. Conclusions. In our series of AMD patients, grade of continuity of outer retinal layers was not a significant predictive value for visual acuity development after triple ranibizumab injections.
Eŭrazio ekde 1928 ĝis 1932 per biciklo kaj Esperanto : Eltiroj de ĉiuj personaj notoj (p. 152)
Creators: name: Péraire, Lucien
name: CNRS
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2023

description: Eltiraĵoj
Cubitermes planifrons Sjostedt 1924
Creators: name: Josens, Guy
name: Deligne, Jean
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Termitidae
Cubitermes
Cubitermes planifrons

description: Cubitermes planifrons Sjöstedt, 1924
CAMEROON • 1 ♀ (queen), 1 soldier, 1 worker; Bipindi; 1920; AMNH • 1 soldier, 1 worker; Somalomo; 3 Mar. 2015; ULB.
DEMOCRATIC REPUBLIC OF THE CONGO • 1 soldier, 1 worker, syntypes; Bas-Congo, Mukimbungu; 1904?; AMNH.
description: Published as part of Josens, Guy & Deligne, Jean, 2019, Species groups in the genus Cubitermes (Isoptera: Termitidae) defined on the basis of enteric valve morphology, pp. 1-72 in European Journal of Taxonomy 515 on page 44, DOI: 10.5852/ejt.2019.515, http://zenodo.org/record/2638175
FysikLab@SDU-Galaxy: Project-based learning & didactics. Grundskolebesøg. FysikLab får besøg af 20 elever fra Sanderumskolen. 07. januar 2025.
Creators: name: Hinse, Tobias Cornelius
Publisher: name: Zenodo
Year: 2025

description: SDU / FKF FysikLab fik besøg af 20 elever fra Sanderumskolen. Udover at lære nyt om exoplaneter så blev elever sat i gang med at måle højden af verdens størst fyrværkerieksplosion som in-class hands-on aktivitet. Der blev talt om rollen af antagelser i fysikken, foretaget håndtegninger af fysiske forhold på et stykke papir og det blev slået fast med en syv-tomme søm, at lyd udbreder sig meget langsommere end lys som resultat af fortolkning af observationer.
Lasioglossum (Habralictellus) eleutherensis
Creators: name: Duarte, Sandra
name: Breto, Dayron
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Halictidae
Lasioglossum
Lasioglossum eleutherensis

description: Lasioglossum (Habralictellus) eleutherensis (Engel)
Habralictellus eleutherensis Engel, 2001. Solenodon 1: 33–37 [36]
Type material examined: Paratypes 1♀ (18.1695), Cuba, Archipiélago Camagüey, Sabana-Camagüey, Cayo Guillermo, 1995-04, leg. I. Fernández; 1♀ (18.1696), ídem, 1995-05, leg. R. Rodríguez.
Remarks: Holotype and 8 paratypes are deposited in FSCA.
description: Published as part of Duarte, Sandra & Breto, Dayron, 2024, Type catalogue of Hymenoptera (Insecta) housed in the Museo Nacional de Historia Natural de Cuba, pp. 301-336 in Zootaxa 5523 (3) on page 317, DOI: 10.11646/zootaxa.5523.3.1, http://zenodo.org/record/13949447
Neoncotympana leeseungmoi Lee 2011
Creators: name: Lee, Young June
name: Marshall, David C.
name: Mohagan, Alma B.
name: Hill, Kathy B. R.
name: Mohagan, Dave P.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadidae
Neoncotympana
Neoncotympana leeseungmoi

description: 17. Neoncotympana leeseungmoi Lee 2011
Neoncotympana leeseungmoi Lee 2011: 169–171, fig. 2 [TL: Mt. Kitanlad Intavas, Mindanao]; Lee 2015: 551.
Additional material examined
2 males, specimen code 12. PH. MN.KGS.05 and 12. PH. MN.KGS. 06, PHILIPPINES, Mindanao, Mt. Kitanglad, 1773 m, 08°09.91 ʹ N, 124°55.96 ʹ E, 4 May 2012, K.B. R. Hill, D.C. Marshall, D. Mohagan and T. Catanach (UCONN); 1 female, PHILIPPINES, Mindanao, Cotabato, Mt. Apo, Agro-ecosystem (Sudsuwayan), 25 May 2010, D. Mohagan (UCONN).
Distribution
Philippines (Mindanao).
description: Published as part of Lee, Young June, Marshall, David C., Mohagan, Alma B., Hill, Kathy B. R. & Mohagan, Dave P., 2023, Revised checklist of Cicadidae (Insecta: Hemiptera) of Mindanao, Philippines, with descriptions of a new genus and nine new species, pp. 193-242 in Journal of Natural History 57 (1 - 4) on page 216, DOI: 10.1080/00222933.2023.2171820, http://zenodo.org/record/7737268
Cubitermes speciosus Sjostedt 1924
Creators: name: Josens, Guy
name: Deligne, Jean
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Termitidae
Cubitermes
Cubitermes speciosus

description: Cubitermes speciosus Sjöstedt, 1924
DEMOCRATIC REPUBLIC OF THE CONGO • 1 ♀ (queen), 1 soldier, 1 worker, syntypes; Haut-Uélé, Moto; 1923; RMCA • 1 ♀ (queen), 3 ♀♀ (alates), 2 ♂♂ (alates), 3 soldiers, 2 workers; Haut-Uélé, Moto; 1920–1922; RMCA • 1 ♀ (queen), 1 soldier, 1 worker; Kisangani, Masako reserve; 1990?; ULB.
description: Published as part of Josens, Guy & Deligne, Jean, 2019, Species groups in the genus Cubitermes (Isoptera: Termitidae) defined on the basis of enteric valve morphology, pp. 1-72 in European Journal of Taxonomy 515 on page 44, DOI: 10.5852/ejt.2019.515, http://zenodo.org/record/2638175
Elachista mongolica Parenti 1991
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista mongolica

description: Elachista mongolica Parenti, 1991
Elachista mongolica Parenti, 1991: 214. Type locality: Mongolia, Central aimak, 11 km S of Pass Zosijn davaa (Parenti 1991: 214). Holotype ♂, in HNHM.
Subgenus: Elachista; tetragonella species group.
Distribution: Palearctic. Mongolia.
Larval host plant(s): unknown.
Figs.: Parenti (1991).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 94, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
title: Rapport de voyage, Ile de France (1926) : Ligne de New-York, 1954, voyage n°12
Creators: name: Comilia, Jean
name: Delafon, Michel
name: Le Diabat, Jean
name: Tournyol du Clos, Guy
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: Compagnie Générale Transatlantique
subject: Transports maritimes - Histoire
subject: Marine marchande
subject: Journaux de bord

description: Chapitrage : Rapport d'inspecteur - Rapport général / du capitaine - Rapport du commissaire - Rapport du second - Rapport de l'officier de sécurité - Rapport de l'officier de navigation - Rapport du médecin - Rapport contentieux
description: Source: French Lines & Compagnies, 1997 004 5071-07
description: Coverage: 1954-05-14/1954-05-28
Minimally invasive computer-navigated total hip arthroplasty, following the concept of femur first and combined anteversion: design of a blinded randomized controlled trial
Creators: name: Renkawitz, Tobias
name: Haimerl, Martin
name: Dohmen, Lars
name: Gneiting, Sabine
name: Wegner, Melanie
name: Ehret, Nicole
name: Buchele, Claudia
name: Schubert, Mario
name: Lechler, Philipp
name: Worner, Michael
name: Sendtner, Ernst
name: Schuster, Tibor
name: Ulm, Kurt
name: Springorum, Robert
name: Grifka, Joachim
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: CUP PLACEMENT; DISLOCATION; MOTION; RANGE; IMPINGEMENT; REPLACEMENT; ORIENTATION; COMPONENTS; ACCURACY;
subject: 610 Medizin

description: Background: Impingement can be a serious complication after total hip arthroplasty (THA), and is one of the major causes of postoperative pain, dislocation, aseptic loosening, and implant breakage. Minimally invasive THA and computer-navigated surgery were introduced several years ago. We have developed a novel, computer-assisted operation method for THA following the concept of "femur first"/"combined anteversion", which incorporates various aspects of performing a functional optimization of the cup position, and comprehensively addresses range of motion (ROM) as well as cup containment and alignment parameters. Hence, the purpose of this study is to assess whether the artificial joint's ROM can be improved by this computer-assisted operation method. Second, the clinical and radiological outcome will be evaluated. Methods/Design: A registered patient-and observer-blinded randomized controlled trial will be conducted. Patients between the ages of 50 and 75 admitted for primary unilateral THA will be included. Patients will be randomly allocated to either receive minimally invasive computer-navigated "femur first" THA or the conventional minimally invasive THA procedure. Self-reported functional status and health-related quality of life (questionnaires) will be assessed both preoperatively and postoperatively. Perioperative complications will be registered. Radiographic evaluation will take place up to 6 weeks postoperatively with a computed tomography (CT) scan. Component position will be evaluated by an independent external institute on a 3D reconstruction of the femur/ pelvis using image-processing software. Postoperative ROM will be calculated by an algorithm which automatically determines bony and prosthetic impingements. Discussion: In the past, computer navigation has improved the accuracy of component positioning. So far, there are only few objective data quantifying the risks and benefits of computer navigated THA. Therefore, this study has been designed to compare minimally invasive computer-navigated "femur first" THA with a conventional technique for minimally invasive THA. The results of this trial will be presented as soon as they become available. Trial registration number: DRKS00000739
Treatment-emergent adverse events after infusion of adherent stem cells: the MiSOT-I score for solid organ transplantation
Creators: name: Dillmann, Johannes
name: Popp, Felix C.
name: Fillenberg, Barbara
name: Zeman, Florian
name: Eggenhofer, Elke
name: Farkas, Stefan
name: Scherer, Marcus N.
name: Koller, Michael
name: Geissler, Edward K.
name: Deans, Robert
name: Ladenheim, Deborah
name: Loss, Martin
name: Schlitt, Hans-Jürgen
name: Dahlke, Marc H.
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: ORTHOTOPIC LIVER-TRANSPLANTATION; HEPATIC-ARTERY THROMBOSIS; ADULT PROGENITOR CELLS; VASCULAR COMPLICATIONS; VEIN STENOSIS; RISK-FACTORS; DOPPLER US; THROMBOEMBOLISM; ANAPHYLAXIS; MANAGEMENT; Adherent adult stem cells; Mesenchymal stem cells; Multipotent adult progenitor cells; Solid organ transplantation; Immunotherapy; Scoring adverse events; Phase I trial
subject: 610 Medizin

description: Background: Cellular therapy after organ transplantation is emerging as an intriguing strategy to achieve dose reduction of classical immunosuppressive pharmacotherapy. Here, we introduce a new scoring system to assess treatment-emergent adverse events (TEAEs) of adherent stem cell therapies in the clinical setting of allogeneic liver transplantation (for example, the MiSOT-I trial Eudract CT: 2009-017795-25). Methods: The score consists of three independent modalities (set of parameters) that focus on clinically relevant events early after intravenous or intraportal stem cell infusion: pulmonary toxicity, intraportal-infusional toxicity and systemic toxicity. For each modality, values between 0 (no TEAE) and 3 (severe TEAE) were defined. The score was validated retrospectively on a cohort of n=187 recipients of liver allografts not receiving investigational cell therapy between July 2004 and December 2010. These patients represent a control population for further trials. Score values were calculated for days 1, 4, and 10 after liver transplantation. Results: Grade 3 events were most commonly related to the pulmonary system (3.5% of study cohort on day 4). Almost no systemic-related TEAEs were observed during the study period. The relative frequency of grade 3 events never exceeded 5% over all modalities and time points. A subgroup analysis for grade 3 patients provided no descriptors associated with severe TEAEs. Conclusion: The MiSOT-I score provides an assessment tool to score specific adverse events that may occur after adherent stem cell therapy in the clinical setting of organ transplantation and is thus a helpful tool to conduct a safety study.
Lasioglossum (Habralictellus) engeli Genaro 2001
Creators: name: Duarte, Sandra
name: Breto, Dayron
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Halictidae
Lasioglossum
Lasioglossum engeli

description: Lasioglossum (Habralictellus) engeli Genaro
(Figs. 34–36)
Lasioglossum (Dialictus) engeli Genaro, 2001b. Solenodon 1: 38–44 [42] *
Type material examined: Holotype 1♀ (18.4529), Cuba, Santiago de Cuba, Sierra Maestra, La Gran Piedra, 2001- 06, leg. J. A. Genaro.
Original label data: Gran Piedra / Sierra Maestra / Oriente. CUBA / vi - 2001 / col. J A Genaro [handwritten-printed] // HOLOTYPE / Lasioglossum ♀ / engeli Genaro [red label, handwritten] // 18.4529 [printed].
Allotype 1♂ (18.4530), same type locality, 1956-07, leg. P. Alayo. Paratypes 2♀ (18.6746, 18.6747) and 1 ♂ (18.6748), same type locality, 1963-07, leg. F. de Zayas, P. Alayo and I. García; 1♀ (18.6749), same type locality, 1962-06, leg. P. Alayo; 1♀ (18.6750), same type locality, 1962-06, leg. P. Alayo, F. de Zayas and I. García; 1♀ (18.6751), Sierra Maestra, Turquino, Pico Cardero, 1966-x, leg. I. García; 1♀ (18.6752), Sierra Maestra, Turquino, Pico Cuba, 1963-06, leg. P. Alayo; 1♀ (18.6753), Pico Cuba, 1964-06, leg. I. García.
Remarks: Total number of paratypes: 16, also deposited in FSCA, UKNHM and USNM.
description: Published as part of Duarte, Sandra & Breto, Dayron, 2024, Type catalogue of Hymenoptera (Insecta) housed in the Museo Nacional de Historia Natural de Cuba, pp. 301-336 in Zootaxa 5523 (3) on page 317, DOI: 10.11646/zootaxa.5523.3.1, http://zenodo.org/record/13949447
Leptopsaltriini Moulton 1923
Creators: name: Lee, Young June
name: Marshall, David C.
name: Mohagan, Alma B.
name: Hill, Kathy B. R.
name: Mohagan, Dave P.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadidae

description: Tribe LEPTOPSALTRIINI Moulton, 1923
Remarks
Hill et al. (2021) noted molecular phylogenetic evidence of confusion between the tribes Gaeanini Distant, 1905 and Leptopsaltriini Moulton, 1923 and suggested that Gaeanini could perhaps be redefined as a subtribe within Leptopsaltriini. However, in such a case tribe Gaeanini would take priority since it is the older family group. In this paper, we refrain from synonymising Leptopsaltriini with Gaeanini, awaiting a further comprehensive morphological review.
description: Published as part of Lee, Young June, Marshall, David C., Mohagan, Alma B., Hill, Kathy B. R. & Mohagan, Dave P., 2023, Revised checklist of Cicadidae (Insecta: Hemiptera) of Mindanao, Philippines, with descriptions of a new genus and nine new species, pp. 193-242 in Journal of Natural History 57 (1 - 4) on page 216, DOI: 10.1080/00222933.2023.2171820, http://zenodo.org/record/7737268
Maria - Hoffnungslos entferntes Ideal oder Schwester im Glauben
Creators: name: Herzig, Anneliese
Publisher: name: Ordenskorrespondenz
Year: 1970

description: Ordenskorrespondenz, Bd. 33 (1992): Ordenskorrespondenz: Zeitschrift für Fragen des Ordenslebens, Band 33
Elachista morandinii Huemer & Kaila 2002
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista morandinii

description: Elachista morandinii Huemer & Kaila, 2002
Elachista morandinii Huemer & Kaila, 2002: 212. Type locality: Italy, Friuli, Giulia (Huemer & Kaila 2002: 212). Holotype ♂, in MFSN.
Biselachista morandinii: Parenti & Pizzolato (2015b: 544).
Subgenus: Elachista; tetragonella species group.
Distribution: Palearctic. Italy, Hungary.
Larval host plant(s): unknown.
Figs.: Huemer & Kaila (2002), Parenti & Pizzolato (2015b).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 94, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Euterpnosiina Lee 2013
Creators: name: Lee, Young June
name: Marshall, David C.
name: Mohagan, Alma B.
name: Hill, Kathy B. R.
name: Mohagan, Dave P.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadidae

description: Subtribe EUTERPNOSIINA Lee, 2013
Euterpnosiina Lee, 2013 in Lee and Emery, 2013: 527–528.
Remarks
The position of the new genus described immediately below is unique and independent from any other known species of Leptopsaltriini in the phylogenetic tree constructed by Hill et al. (2021). Therefore, this genus could form a separate new subtribe within Leptopsaltriini. This genus has very long fore wing apical cells, which is one of its peculiar characteristics within Leptopsaltriini, and has tubercle-like projections only on the sternite III, which is seen only in some members of Tanna Distant, 1905 and Vietanna Lee and Pham, 2021. This genus is different from the genera of Puranina Lee, 2013 because of the anterolateral pronotal collar which is not dentate, the male abdominal sternite IV which does not have tubercle-like projections, and the aedeagus which is thick apically.
This genus is tentatively placed in Euterpnosiina because the type specimen of the genus was largely grouped with genera of Euterpnosiina in the phylogenetic tree constructed by Hill et al. (2021) in spite of many morphological differences, including the following: timbal cover well developed (vs minute in Euterpnosiina); male abdominal sternite III with tubercle-like projections (vs mostly without them in Euterpnosiina); aedeagus thick (vs thin in Euterpnosiina); and basal lobe of pygofer absent (vs present in Euterpnosiina). Further taxonomic study is required to find its proper subtribe placement.
description: Published as part of Lee, Young June, Marshall, David C., Mohagan, Alma B., Hill, Kathy B. R. & Mohagan, Dave P., 2023, Revised checklist of Cicadidae (Insecta: Hemiptera) of Mindanao, Philippines, with descriptions of a new genus and nine new species, pp. 193-242 in Journal of Natural History 57 (1 - 4) on page 217, DOI: 10.1080/00222933.2023.2171820, http://zenodo.org/record/7737268
Cubitermes subarquatus Sjostedt 1926
Creators: name: Josens, Guy
name: Deligne, Jean
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Termitidae
Cubitermes
Cubitermes subarquatus

description: Cubitermes subarquatus Sjöstedt, 1926
CAMEROON • 1 soldier, 1 worker; Kala; Apr. 1992; RMCA • 1 soldier, 1 worker; Nkolbison; Jun. 1992; RMCA.
DEMOCRATIC REPUBLIC OF THE CONGO • 1 ♀ (queen), 1 soldier, 1 worker, syntypes; Lubila; 20 Sep. 1919; AMNH • 1 soldier, 1 worker, syntypes; Lubila; 20 Sep. 1919; RMCA.
description: Published as part of Josens, Guy & Deligne, Jean, 2019, Species groups in the genus Cubitermes (Isoptera: Termitidae) defined on the basis of enteric valve morphology, pp. 1-72 in European Journal of Taxonomy 515 on page 44, DOI: 10.5852/ejt.2019.515, http://zenodo.org/record/2638175
Elachista multidentella Sinev & Sruoga 1995
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista multidentella

description: Elachista multidentella Sinev & Sruoga, 1995
Elachista multidentella Sinev & Sruoga, 1995: 125. Type locality: Russia, Kurils, Kunashir, okresnosti Cernovodska (Sinev & Sruoga 1995: 125).
Subgenus: Elachista; bifasciella species group.
Distribution: Palearctic. Russia (Kurils).
Larval host plant(s): unknown.
Figs.: Sinev & Sruoga (1995).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 94, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
Influence of surface processing on the biocompatibility of titanium
Creators: name: Wirsching, Kornelia
name: Lehle, Karla
name: Jacob, Peter
name: Gleich, Otto
name: Strutz, Jürgen
name: Kwok, Pingling
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: OSSICULAR REPLACEMENT PROSTHESES; MIDDLE-EAR; IMPLANTS; RECONSTRUCTION; CHAIN; biocompatibility; Titanium surface processing; Titanium ossicular implant; Kurz
subject: 610 Medizin

description: Surface conditioning of titanium middle ear implants results in an improved biocompatibility, which can be characterized by the properties of fibroblasts cultured on conditioned surfaces. Titanium has been established as a favorable biomaterial in ossicular chain reconstruction. The epithelization of the surface of the implants is important for their integration and stable positioning in the middle ear. Mouse fibroblast cells were cultured on platelets made from pure Grade 2 titanium. Platelets that had been etched along their production process were compared to unetched platelets. The DNA in the cell nuclei was stained with DAPI and the actin filaments of the cytoskeleton were stained with FITC-conjugated phalloidin in order to analyze the cells grown on etched and unetched platelets by fluorescence microscopy. SEM (scanning electron microscopic) images were used to compare the surface structure of etched and unetched titanium platelets. There was a statistically significant increase of the area covered by the cytoplasm and increased actin expression by fibroblasts grown on the etched titanium platelets. In addition, the area of the platelets covered by nuclei on the etched platelets exceeded on average the one on unetched platelets, although this difference was not significant. The SEM pictures comparing unetched and etched titanium platelets showed a clear difference in surface structure. Surface conditioning of titanium implants improved the epithelization by fibroblasts and consequently etched titanium should be the preferred biomaterial for reconstructive middle ear surgery.
Neopurana Lee and Marshall 2023, gen. nov.
Creators: name: Lee, Young June
name: Marshall, David C.
name: Mohagan, Alma B.
name: Hill, Kathy B. R.
name: Mohagan, Dave P.
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Cicadidae
Neopurana

description: Genus Neopurana Lee and Marshall gen. nov.
Type species
Neopurana bouptera Lee and Marshall sp. nov., monotypic.
Etymology
The generic name is feminine, a combination of the Greek prefix neo- meaning ̍new̾ and the name of an allied genus, Purana.
Description
Body small-sized (24.4 mm long in holotype of the type species). Head including compound eyes (6.8 mm wide in holotype) about as wide as mesonotum (6.7 mm wide in holotype). Postclypeus moderately swollen. Rostrum slightly passing beyond hind coxae. Anterolateral pronotal collar not dentate. Wings hyaline. Fore wing with infuscations on crossveins and along its hind submargin. Fore wing with very long apical cells, with ulnar cell 2 about as long as apical cell 4. Male operculum small, about as long as wide, extending to anterior margin of abdominal sternite III. Opercula widely separated from each other. Male abdomen long obconical, distinctly longer than head and thorax together. Male abdominal tergite 3 wider than mesonotum. Timbal cover about as long as wide, concealing timbal in dorsal view. Male abdominal sternite III with tubercle-like projection on each posterolateral surface, long protruding posteriorly. Male pygofer oval in ventral view. Uncus simple, short, not bifurcate. Distal shoulder not pointed. Basal lobe of pygofer absent.
Remarks
Neopurana Lee and Marshall gen. nov. resembles various species and species groups of the genus Purana Distant, 1905 in the following characters, and especially in the similarlooking marks and patterns on the mesonotum: body small-sized; wings hyaline; male operculum small; and male abdominal sternite III with tubercle-like projection on each lateral surface. However, this genus can be distinguished from Purana by the following characteristics: anterolateral pronotal collar not dentate; fore wing with very long apical cells; male abdominal sternite IV without tubercle-like projections; and aedeagus thick apically. This genus can be distinguished from all other genera of Puranina Lee, 2013 by the fore wing with very long apical cells and the aedeagus very thick apically (as illustrated in Figure 11 (C)).
description: Published as part of Lee, Young June, Marshall, David C., Mohagan, Alma B., Hill, Kathy B. R. & Mohagan, Dave P., 2023, Revised checklist of Cicadidae (Insecta: Hemiptera) of Mindanao, Philippines, with descriptions of a new genus and nine new species, pp. 193-242 in Journal of Natural History 57 (1 - 4) on pages 217-218, DOI: 10.1080/00222933.2023.2171820, http://zenodo.org/record/7737268
Cubitermes undetermined
Creators: name: Josens, Guy
name: Deligne, Jean
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Termitidae
Cubitermes
Cubitermes undetermined

description: Unknown, new species
DEMOCRATIC REPUBLIC OF THE CONGO •, 1 ♀ (queen), 1 soldier, 1 worker; Kasaï, Kondué; 1905; RMCA • 1 soldier, 1 worker; Kinshasa, Bateke Plateau, Duale; Jan. 2011; ULB • 1 soldier, 1 worker; Kinshasa, Bateke Plateau, Bombo-Lumene reserve; 22 Apr. 2017; ULB.
The above were all collected only in Central Africa (Fig. 16C).
description: Published as part of Josens, Guy & Deligne, Jean, 2019, Species groups in the genus Cubitermes (Isoptera: Termitidae) defined on the basis of enteric valve morphology, pp. 1-72 in European Journal of Taxonomy 515 on page 44, DOI: 10.5852/ejt.2019.515, http://zenodo.org/record/2638175
Curcumin is a potent modulator of microglial gene expression and migration
Creators: name: Karlstetter, Marcus
name: Lippe, Elena
name: Walczak, Yana
name: Moehle, Christoph
name: Aslanidis, Alexander
name: Mirza, Myriam
name: Langmann, Thomas
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: IN-VIVO; PARKINSONS-DISEASE; BRAIN MICROGLIA; IMMUNE-SYSTEM; CELLS; RECEPTOR; ACTIVATION; MACROPHAGES; NEUROTOXICITY; PHENOTYPE;
subject: 610 Medizin

description: Background: Microglial cells are important effectors of the neuronal innate immune system with a major role in chronic neurodegenerative diseases. Curcumin, a major component of tumeric, alleviates pro-inflammatory activities of these cells by inhibiting nuclear factor kappa B ( NFkB) signaling. To study the immuno-modulatory effects of curcumin on a transcriptomic level, DNA-microarray analyses were performed with resting and LPS-challenged microglial cells after short-term treatment with curcumin. Methods: Resting and LPS-activated BV-2 cells were stimulated with curcumin and genome-wide mRNA expression patterns were determined using DNA-microarrays. Selected qRT-PCR analyses were performed to confirm newly identified curcumin-regulated genes. The migration potential of microglial cells was determined with wound healing assays and transwell migration assays. Microglial neurotoxicity was estimated by morphological analyses and quantification of caspase 3/7 levels in 661W photoreceptors cultured in the presence of microglia-conditioned medium. Results: Curcumin treatment markedly changed the microglial transcriptome with 49 differentially expressed transcripts in a combined analysis of resting and activated microglial cells. Curcumin effectively triggered anti-inflammatory signals as shown by induced expression of Interleukin 4 and Peroxisome proliferator activated receptor a. Several novel curcumin-induced genes including Netrin G1, Delta-like 1, Platelet endothelial cell adhesion molecule 1, and Plasma cell endoplasmic reticulum protein 1, have been previously associated with adhesion and cell migration. Consequently, curcumin treatment significantly inhibited basal and activation-induced migration of BV-2 microglia. Curcumin also potently blocked gene expression related to pro-inflammatory activation of resting cells including Toll-like receptor 2 and Prostaglandin-endoperoxide synthase 2. Moreover, transcription of NO synthase 2 and Signal transducer and activator of transcription 1 was reduced in LPS-triggered microglia. These transcriptional changes in curcumin-treated LPS-primed microglia also lead to decreased neurotoxicity with reduced apoptosis of 661W photoreceptor cultures. Conclusions: Collectively, our results suggest that curcumin is a potent modulator of the microglial transcriptome. Curcumin attenuates microglial migration and triggers a phenotype with anti-inflammatory and neuroprotective properties. Thus, curcumin could be a nutraceutical compound to develop immuno-modulatory and neuroprotective therapies for the treatment of various neurodegenerative disorders.
title: Activité du port de Saint-Malo – 1763 – Cherbourg
Creators: name: :Unkn
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2024
Subjects: subject: produits manufacturés
subject: armes et munitions

description: Cette fiche est issue de l’enquête menée par Jean Delumeau sur l’activité du port de Saint-Malo au 17e et 18e siècle. Cette fiche correspond à l’activité de l’année 1763 avec le port "Cherbourg"
description: Marchandises au départ de Saint-Malo : funain ; cordages
description: Catégories de marchandises au départ de Saint-Malo : produits manufacturés
description: Marchandises arrivées à Saint-Malo : canons
description: Catégories de marchandises arrivées à Saint-Malo : produits manufacturés ; armes et munitions
description: Coverage: Petit cabotage
description: Bibliographic citation: CHEREL, Huguette. L'Activité du port de Saint-Malo en 1763. DES : Histoire : Rennes : 1967 (Bibliothèque François-Lebrun, MH 1052)
description: date: Date de numérisation : 2021 à 2023
description: created: Années 1950-1960
Characteristics of “Tip-DCs and MDSCs” and their potential role in leishmaniasis
Creators: name: Schmid, Maximilian
name: Wege, Anja K.
name: Ritter, Uwe
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: dendritic cell; myeloid suppressor cell; nitric oxide synthase; Langerhans cells; Leishmania parasites
subject: 610 Medizin

description: Since the first description of dendritic cells (DCs) by Steinman and Cohn (1973), the myeloid lineage of leukocytes was investigated intensively. Nowadays it is obvious that myeloid cells, especially DCs, are crucial for the adaptive and innate immune response against intracellular pathogens such as Leishmania major parasites. Based on the overlapping expression of molecules that were commonly used to classify myeloid cells, it becomes difficult to denominate those cell types precisely. Of note, most of these markers used for myeloid cell identification are expressed on a broad range of myeloid cells, and should therefore be handled with care if used for subtyping of myeloid cells. In this mini-review we aim to discuss the relative impact of DCs that release TNF and nitric oxide (Tip-DCs) and myeloid cells with suppressive capacities (myeloid-derived suppressor cells, MDSCs) in infectious diseases such as experimental leishmaniasis. In our point of view it cannot be excluded that the novel subsets that were denominated as "Tip-DCs" and "MDSCs" might not be classical "subsets" but rather represent myeloid cells in a transient maturation stage expressing different genes, in response to the surrounding environment.
Annotations on ostraca from North Africa
Creators: name: Robert Marichal ##[Hubert]
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2015

description: vue 14
description: Annotations, photos and bibliography. - Letter from Hubert. - Three articles by J. F. Gilliam, "BASP" 13 (1976).
description: Source: 4MAR_15_2.7-5-3
description: Relation: [Hubert]
description: Coverage: North Africa
description: created: n. d.
Clostridium difficile-associated diarrhea in radiooncology: an underestimated problem for the feasibility of the radiooncological treatment?
Creators: name: Hautmann, Matthias
name: Hipp, Matthias
name: Kölbl, Oliver
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: PROTON PUMP INHIBITORS; TREATMENT TIME; RISK-FACTORS; NECK-CANCER; CONCURRENT CHEMORADIATION; HOSPITALIZED-PATIENTS; WEEKLY CISPLATIN; INFECTION; RADIOTHERAPY; HEAD; Clostridium difficile-associated diarrhea; Clostridium difficile; Diarrhea; Colitis; Radiotherapy; Radiation Therapy; Chemoradiation
subject: 610 Medizin

description: Background and Purpose: Over the last years an increasing incidence of Clostridium difficile-associated diarrhea (CDAD) has been reported. Especially haematology-oncology patients are at risk of developing CDAD. The aim of this analysis is to determine the incidence of CDAD in radiooncological patients and to find out what relevance CDAD has for the feasibility of the radiooncological treatment, as well as to detect and describe risk factors. Patients and Methods: In a retrospective analysis from 2006 to 2010 34 hospitalized radiooncological patients could be identified having CDAD. The risk factors of these patients were registered, the incidence was calculated and the influence on the feasibility of the radiooncological therapy was evaluated. Induced arrangements for prophylaxis of CDAD were identified and have been correlated with the incidence. Results: The incidence of CDAD in our collective is 1,6%. Most of the patients suffering from a CDAD were treated for carcinoma in the head and neck area. Common risk factors were antibiotics, proton pump inhibitors, cytostatic agents and tube feeding. Beside a high rate of electrolyte imbalance and hypoproteinemia a decrease of general condition was frequent. 12/34 patients had a prolonged hospitalization, in 14/34 patients radiotherapy had to be interrupted due to CDAD. In 21 of 34 patients a concomitant chemotherapy was planned. 4/21 patients could receive all of the planned cycles and only 2/21 patients could receive all of the planned cycles in time. 4/34 patients died due to CDAD. In 4/34 patients an initially curative treatment concept has to be changed to a palliative concept. With intensified arrangements for prophylaxis the incidence of CDAD decreased from 4,0% in 2007 to 0,4% in 2010. Conclusion: The effect of CDAD on the feasibility of the radiotherapy and a concomitant chemotherapy is remarkable. The morbidity of patients is severe with a high lethality. Reducing of risk factors, an intense screening and the use of probiotics as prophylaxis can reduce the incidence of CDAD.
Lasioglossum (Habralictellus) sierramaestrensis Genaro 2001
Creators: name: Duarte, Sandra
name: Breto, Dayron
Publisher: name: Zenodo
Year: 2024
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Halictidae
Lasioglossum
Lasioglossum sierramaestrensis

description: Lasioglossum (Habralictellus) sierramaestrensis Genaro
(Figs. 37–38)
Lasioglossum (Dialictus) sierramaestrensis Genaro, 2001b. Solenodon 1: 38–44 [40] *
Type material examined: Holotype 1♀ (18.4527), Cuba, Santiago de Cuba, Sierra Maestra, La Gran Piedra, 2001- 06, leg. J. A. Genaro.
Original label data: Gran Piedra / Sierra Maestra / Oriente. CUBA / vi - 2001 / col. JA Genaro [handwritten-printed] // HOLOTYPE / Lasioglossum ♀ / sierramaestresis [sic] / Genaro [red label, handwritten] // 18.4527 [printed].
Allotype 1♂ (18.4528), Cuba, Oriente, Pico Turquino, 1963-06, leg. F. Zayas, P. Alayo and I. García. Paratypes 1♀ (18.6754), same type locality, 1963-07, leg. F. de Zayas, P.Alayo and I. García; 1 ♂ (18.6755), same type locality, 1962-06, leg. P. Alayo; 1♀ (18.6756), same type locality, 1969-05, leg. I. García; 2♀ (18.6757, 18.6758), same type locality, 1969-05, leg. N. Novoa; 1♀ (18.6759), same type locality, 1969-05, leg. R. G. Broche; 1♂ (18.6760, vial with genitalia), same type locality, 1969-05, leg. P. Alayo; 1♀ (18.6761), same type locality, 1964-05, leg. I. García; 1♀ (18.6762), same type locality, 1954-06, leg. F. Zayas and P. Alayo; 1♀ (18.6763), same type locality, 1955- 04, leg. P. Alayo; 1♀ (18.6764), same type locality, 1956-04-29, leg. P. Alayo; 5♀ (18.6765 – 18.6769), same type locality, 2001-vi, leg. J. Genaro; 2♀ (18.6770, 18.6771), Sierra Maestra, Turquino, Pico Cardero, 1963-06, leg. F. de Zayas, P. Alayo and I. García; 1♀ (18.6772), Sierra Maestra, Pico Turquino, 1967-12, leg. P. Alayo; 1♀ (18.6773), Sierra del Cobre, Loma del Gato, 1952-06-20, leg. P. Alayo; 1♀ (18.6774, vial with genitalia), Santiago de Cuba, El Cobre, Loma del Gato, 2600–3325 feets, 1935-09-24 /30, leg. J. Acuña, S. C. Bruner and L. C. Scaramuzza, (EEA Cuba, Ento. No. 10723).
Remarks: Total number of paratypes: 36, also deposited in IES, FSCA, UKNHM and USNM.
description: Published as part of Duarte, Sandra & Breto, Dayron, 2024, Type catalogue of Hymenoptera (Insecta) housed in the Museo Nacional de Historia Natural de Cuba, pp. 301-336 in Zootaxa 5523 (3) on pages 320-321, DOI: 10.11646/zootaxa.5523.3.1, http://zenodo.org/record/13949447
Cubitermes niokoloensis Roy-Noel 1969
Creators: name: Josens, Guy
name: Deligne, Jean
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Blattodea
Termitidae
Cubitermes
Cubitermes niokoloensis

description: Cubitermes niokoloensis Roy-Noël, 1969
SENEGAL • 1 ♀ (alate), 1 soldier, paratypes; Bangare-Niokolo-Koba road; Jan. 1965; AMNH.
description: Published as part of Josens, Guy & Deligne, Jean, 2019, Species groups in the genus Cubitermes (Isoptera: Termitidae) defined on the basis of enteric valve morphology, pp. 1-72 in European Journal of Taxonomy 515 on page 47, DOI: 10.5852/ejt.2019.515, http://zenodo.org/record/2638175
Elachista napaea Philpott 1930
Creators: name: Kaila, Lauri
Publisher: name: Zenodo
Year: 2019
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Elachistidae
Elachista
Elachista napaea

description: Elachista napaea Philpott, 1930
Elachista napaea Philpott, 1930: 438. Type locality: New Zealand, Governor’s Bush, Mount Cook (Philpott 1930: 439). Holotype ♂, in CMNZ.
Subgenus: Elachista; bifasciella species group.
Distribution: Australasian. New Zealand.
Larval host plant(s): unknown.
Figs.: Hudson (1939).
description: Published as part of Kaila, Lauri, 2019, An annotated catalogue of Elachistinae of the World (Lepidoptera: Gelechioidea: Elachistidae), pp. 1-231 in Zootaxa 4632 (1) on page 95, DOI: 10.11646/zootaxa.4632.1.1, http://zenodo.org/record/3335414
The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro
Creators: name: Lechler, Philipp
name: Renkawitz, Tobias
name: Campean, Valentina
name: Balakrishnan, Sanjeevi
name: Tingart, Markus
name: Grifka, Joachim
name: Schaumburger, Jens
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: CANCER; APOPTOSIS; PROTEIN; BONE; REVEALS; TARGET;
subject: 610 Medizin

description: Background: Chondrosarcoma is virtually resistant to chemotherapy and radiation therapy. Survivin, the smallest member of the inhibitor of apoptosis protein family, is a critical factor for tumor progression and resistance to conventional therapeutic approaches in a wide range of malignancies. However, the role of survivin in chondrosarcoma has not been well studied. We examined the importance of survivin gene expression in chondrosarcoma and analysed its influences on proliferation, apoptosis and resistance to chemotherapy in vitro. Methods: Resected chondrosarcoma specimens from which paraffin-embedded tissues could be extracted were available from 12 patients. In vitro experiments were performed in human chondrosarcoma cell lines SW1353 and Hs819.T. Immunohistochemistry, immunoblot, quantitative PCR, RNA interference, gene-overexpression and analyses of cell proliferation and apoptosis were performed. Results: Expression of survivin protein was detected in all chondrosarcoma specimens analyzed, while undetectable in adult human cartilage. RNA interference targeting survivin resulted in a G(2)/M-arrest of the cell cycle and led to increased rates of apoptosis in chondrosarcoma cells in vitro. Overexpression of survivin resulted in pronounced resistance to doxorubicin treatment. Conclusions: These findings indicate that survivin plays a role in the pathogenesis and pronounced chemoresistance of high grade chondrosarcoma. Survivin antagonizing therapeutic strategies may lead to new treatment options in unresectable and metastasized chondrosarcoma.
Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation - a phase I study (MISOT-I).
Creators: name: Popp, Felix C.
name: Fillenberg, Barbara
name: Eggenhofer, Elke
name: Renner, Philipp
name: Dillmann, Johannes
name: Benseler, Volker
name: Schnitzbauer, Andreas A.
name: Hutchinson, James
name: Deans, Robert
name: Ladenheim, Deborah
name: Graveen, Cheryl A.
name: Zeman, Florian
name: Koller, Michael
name: Hoogduijn, Martin J.
name: Geissler, Edward K.
name: Schlitt, Hans J.
name: Dahlke, Marc H.
Publisher: name: Universität Regensburg
Year: 2011
Subjects: subject: MESENCHYMAL STEM-CELLS; REGULATORY T-CELLS; SOLID-ORGAN TRANSPLANTATION; VERSUS-HOST-DISEASE; RISK-FACTORS; TOLERANCE; RECIPIENTS; CYCLOSPORINE; INFECTIONS; SURVIVAL;
subject: 610 Medizin

description: Background: Liver transplantation is the definitive treatment for many end-stage liver diseases. However, the lifelong immunosuppression needed to prevent graft rejection causes clinically significant side effects. Cellular immunomodulatory therapies may allow the dose of immunosuppressive drugs to be reduced. In the current protocol, we propose to complement immunosuppressive pharmacotherapy with third-party multipotent adult progenitor cells (MAPCs), a culture-selected population of adult adherent stem cells derived from bone marrow that has been shown to display potent immunomodulatory and regenerative properties. In animal models, MAPCs reduce the need for pharmacological immunosuppression after experimental solid organ transplantation and regenerate damaged organs. Methods: Patients enrolled in this phase I, single-arm, single-center safety and feasibility study (n = 3-24) will receive 2 doses of third-party MAPCs after liver transplantation, on days 1 and 3, in addition to a calcineurin-inhibitor-free "bottom-up" immunosuppressive regimen with basiliximab, mycophenolic acid, and steroids. The study objective is to evaluate the safety and clinical feasibility of MAPC administration in this patient cohort. The primary endpoint of the study is safety, assessed by standardized dose-limiting toxicity events. One secondary endpoint is the time until first biopsy-proven acute rejection, in order to collect first evidence of efficacy. Dose escalation (150, 300, 450, and 600 million MAPCs) will be done according to a 3 + 3 classical escalation design (4 groups of 3-6 patients each). Discussion: If MAPCs are safe for patients undergoing liver transplantation in this study, a phase II/III trial will be conducted to assess their clinical efficacy.