cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
How Likely Special UN Adviser Jeffrey Sachs Has Been Bribed by China
Creators: name: Yuan, Ji
Publisher: name: Zenodo
Year: 2021
Subjects: Jeffrey Sachs
China
United Nations
covid
coronavirus
bribery
conflict of interest

description: Jeffrey Sachs,chair of the Lancet Covid-19 Commission that oversees task forces to combat the coronavirus pandemic and prevent future outbreaks, said that US and China need to put aside differences and work together to set new safety standards for laboratories doing virus research, ignoring the fact that it was China that didn't cooperation with international cooperation. To understand the background of his absurd words, it's necessary to assess how likely Special UN Adviser Jeffrey Sachs has been bribed by China throught exploring the news reports made in Chinese. Jeffrey Sachs is likely to have been engaged in bribery, human rights abuses and crime against humanity.
title: Axiologie et enseignement scolaire de l'histoire
title: Axiologie et enseignement scolaire de l'histoire
titleType: AlternativeTitle
Creators: name: Porat, Ary Daniel
Publisher: name: Unknown
Year: 0
Subjects: subject: axiologie
subject: enseignement scolaire de l’histoire
subject: praxéologie
subject: histoire patriotique
subject: société multiculturelle
subject: ouverture à l’Autre

description: Ce mémoire aborde la nature et la place de l’axiologie dans l’enseignement scolaire de l’histoire à partir de l’analyse des Plans d’études de formations post-obligatoires vaudois (École de maturité, École de culture générale). Partant du principe d’une forte cohérence entre les différents axes d’une didactique, il démontre en outre les liens intrinsèques entre la praxéologie de la discipline et ses valeurs citoyennes choisies. Pour ce faire, il compare, par contraste, l’axiologie de l’école patriotique (XIXe-1970) d’autrefois avec celle d’aujourd’hui tout en dégageant les nombreux choix philosophiques sous-jacents à cette dernière, il inscrit notamment les Plans d’études dans les circonstances historiques qui les surplombent (1970-2020). Il se structure en quatre parties. La première analyse la trame de fond axiologique des Plans d’études qui n’est autre que la valeur d’ « ouverture à l’Autre ». La seconde, démontre en quoi le rapport critique à l’histoire, dans sa praxis, corrobore les valeurs mises en exergue. La troisième renvoie à une autre fonction axiologique de l’enseignement scolaire de l’histoire, c’est-à-dire sa capacité à initier les élèves à la vie civique et politique. Quatrièmement et finalement, la réflexion se penche sur le caractère à la fois socio-centré et libéral de l’axiologie en question.
Relative Entropy of Entanglement for Two-Qubit State with $z$-directional Bloch Vectors
Creators: name: Park, DaeKil
Publisher: name: arXiv
Year: 2010
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: So far there is no closed formula for relative entropy of entanglement of arbitrary two-qubit states. In this paper we present a method, which guarantees the derivation of the relative entropy of entanglement for most states that have $z$-directional Bloch vectors. It is shown that the closest separable states for those states also have $z$-directional Bloch vectors though there are few exceptions.
description: 12pages, no figure, will appear in IJQI
The order of the deconfinement phase transition in a heavy quark mass region
Creators: name: Saito, H.
name: Aoki, S.
name: Kanaya, K.
name: Ohno, H.
name: Ejiri, S.
name: Hatsuda, T.
name: Maezawa, Y.
name: Umeda, T.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Lattice (hep-lat)
subject: FOS: Physical sciences

description: We study the quark mass dependence of the QCD phase transition by an effective potential defined through the distribution function of observables. As a test of the method, we study the first order deconfinement phase transition in the heavy quark mass limit and its fate at lighter quark masses. We confirm that the distribution function for the plaquette has two peaks indicating that the phase transition is of first order in the heavy quark limit. We then study the quark mass dependence of the distribution function by a reweighting method combined with the hopping parameter expansion. We find that the first order transition turns into a crossover as the quark mass decreases. We determine the critical point for the cases of $N_f$=1, 2, 3 and 2+1. We find that the probability distribution function provides us with a powerful tool to study the order of transitions.
description: 7 pages, 7 figure, Talk presented at the XXVIII International Symposium on Lattice Field Theory, Lattice2010, Villasimius, Italy, June 2010
IMPROVING THE PROCEDURE FOR CONDUCTING INFORMATION AND ANALYTICAL ACTIVITIES IN INTERNAL AFFAIRS BODIES IS A CURRENT DEMAND OF OUR TIME
Creators: name: Sarabekov, Khasan
Publisher: name: Zenodo
Year: 2025

description: This article examines the issues of improving the procedure for conducting information and analytical activities in internal affairs bodies. Today, the rapid development of modern technologies and information systems, as well as the changes occurring in society, necessitate organizing activities in this field based on new approaches. The article analyzes existing problems in information-analytical processes and develops proposals for increasing their effectiveness. Additionally, the possibilities of studying foreign experiences and adapting them to local conditions are discussed. This research is of great importance in optimizing the activities of internal affairs bodies and ensuring public safety, meeting the demands of our time.
Stories of our ancestors : intergenerational trauma and Chinese-Canadian families
Creators: name: Chou, Fred
Publisher: name: University of British Columbia
Year: 2019

description: Intergenerational trauma (IGT) is a distal determinant of mental health and has been examined in various populations, including Holocaust survivors and Indigenous peoples (Bombay et al., 2009). However, despite the significant historical traumas experienced by Chinese people in the twentieth century (e.g., the Great Famine and the Cultural Revolution), the research on IGT for this population has been limited. To address this gap in the literature, this study examined the following research question: What are the narratives of IGT and resiliency among Chinese-Canadian families? Narratives of IGT among parental and offspring Chinese-Canadians were co-constructed utilizing an adapted version of Arvay’s (2003) Collaborative Narrative Approach. To affirm the multilingual aspect of storytelling, unique methodological considerations (i.e., the Linguistic Ecology Protocol) were integrated into the study. Eight participants took part in the study with four from two parent-offspring dyads. Participants who took part as family dyads shared their co-constructed stories to each other in a reflective dialogue. These dialogues were witnessed by the researcher and incorporated into the study as separate narratives. An across-narrative analysis was conducted utilizing Braun and Clarke’s (2003) thematic analysis. From the analysis ten themes were developed. Five themes were associated with parental experiences: (a) Decimation of Social Structures; (b) Oppression, Chaos, and Abuse; (c) Desperation for Survival; (d) Personal Losses and the Denial of Education and Opportunities; and (e) Maintenance of Values and Emphasis on the Future. While the next five themes consisted of trauma transmission processes and its impact on the offspring generation: (a) Silence, Shame, and Disconnection; (b) Saving Face and the Cultural Framework of Interdependence; (c) Fear and Discipline; (d) Education as Survival and Identity; and (e) Preservation and Reclamation of Heritage. To understand the unique facets of history, trauma, and narrative presented in the analysis and co-constructed stories, a narrative model for Chinese-Canadian IGT is proposed. This model includes: (a) The remembered traumas and the social construction of Chinese-Canadian IGT; (b) intergenerational narrative pathways; and (c) intergenerational narrative identity construction and resilience. The study has implications for counselling psychology in the areas of narrative and multicultural research and family and trauma therapy.
Canonical decompositions and algorithmic recognition of spatial graphs
Creators: name: Friedl, Stefan
name: Munser, Lars
name: Quintanilha, José Pedro
name: Santos Rego, Yuri
Publisher: name: Universität Regensburg
Year: 2024
Subjects: subject: spatial graphs 3-manifolds with boundary pattern Haken manifolds piecewise-linear topology
subject: 510 Mathematik
subject: 57M15: Relations with graph theory
subject: 57Q35: Embeddings and immersions
subject: 57Q40: Regular neighborhoods

description: Abstract:

We prove that there exists an algorithm for determining whether two piecewise-linear spatial graphs are isomorphic. In its most general form, our theorem applies to spatial graphs furnished with vertex colourings, edge colourings and/or edge orientations.

We first show that spatial graphs admit canonical decompositions into blocks, that is, spatial graphs that are non-split and have no cut vertices, in a suitable topological sense. Then, we apply a result of Haken and Matveev in order to algorithmically distinguish these blocks.
Novel Magnetic Phases Revealed by Ultra-High Magnetic Field in the Frustrated Magnet ZnCr2O4
Creators: name: Miyata, Atsuhiko
name: Ueda, Hiroaki
name: Ueda, Yutaka
name: Motome, Yukitoshi
name: Shannon, Nic
name: Penc, Karlo
name: Takeyama, Shojiro
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The Faraday rotation technique is used to map out the finite-temperature phase diagram of the prototypical frustrated magnet ZnCr2O4, in magnetic fields of up to 190 T generated by the single-turn coil method. We find evidence for a number of magnetic phase transitions, which are well-described by the theory based on spin-lattice coupling. In addition to the 1/2 plateau and a 3:1 canted phase, a 2:1:1 canted phase is found for the first time in chromium spinel oxides, which has been predicted by a theory of Penc et al. to realize in a small spin-lattice coupling limit. Both the new 2:1:1 and the 3:1 phase are regarded as the supersolid phases according to a magnetic analogy of Matsuda and Tsuneto, and Liu and Fisher.
description: 13 pages, 6 figures, accepted for publication in JPSJ
Machine learning of lineaments from magnetic, gravity and elevation maps
Creators: name: Aghaee Rad, Mohammad Amin
Publisher: name: University of British Columbia
Year: 2019

description: Minerals exploration is becoming more difficult, particularly because most mineral deposits at the surface of the earth have been found. While there may be a lot of sensing data, there is a shortage of expertise to interpret that data. This thesis aims to bring some of the recent advances in AI to the interpretation of sensing data. Our AI model learns one-dimensional features (lineaments) from two-dimensional data (in particular, magnetics surveys, maps of gravity and digital elevation maps), which surprisingly has not had a great deal of attention (whereas getting two-dimensional or zero-dimensional features is very common). We define a convolutional neural network to predict the probability that a lineament passes through each location on the map. Then, using these probabilities, cluster analysis, and regression models, we develop a post-processing method to predict lineaments. We train and evaluate our model on large real-world datasets in BC and Australia.
Lithium abundances in red giants of M4: evidence for asymptotic giant branch star pollution in globular clusters?
Creators: name: D'Orazi, Valentina
name: Marino, Anna F.
Publisher: name: arXiv
Year: 2010
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The determination of Li and proton-capture element abundances in globular cluster (GC) giants allows us to constrain several key questions on the multiple population scenarios in GCs, from formation and early evolution, to pollution and dilution mechanisms. In this Letter, we present our results on Li abundances for a large sample of giants in the intermediate-metallicity GC NGC 6121 (M4), for which Na and O have been already determined by Marino et al. The stars analyzed are both below and above the red giant branch bump luminosity. We found that the first and second generation stars share the same Li content, suggesting that a Li production must have occurred. This is a strong observational evidence providing support for the scenario in which asymptotic giant branch stars are GC polluters.
description: updated version after proof
title: Ð¡ÑÐµÐ´ÑÑÐ²Ð° Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ Ð½Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÑ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð³Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
title: Tools for estimating labor costs for software development
Creators: name: ÐÑÐ»ÑÐµÐ², ÐÐ½ÑÐ¾Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2023
Subjects: ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°ÑÑ
function points
use case points
COCOMO
agile
ANN
kotlin
view
viewmodel
estimation

description: ÐÐ°Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¿Ð¾ÑÐ²ÑÑÐµÐ½Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐµ ÑÑÐµÐ´ÑÑÐ²Ð° Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ. Ð ÑÐ°Ð±Ð¾ÑÐµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ, Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼ Ð¿Ð¾ÑÑÑÐ¾ÐµÐ½Ð¸Ñ Ð²ÑÐµÐ¼ÐµÐ½Ð½Ð¾Ð¹ Ð´Ð¸Ð°Ð³ÑÐ°Ð¼Ð¼Ñ Ð´Ð»Ñ Ð¿ÑÐ¾ÐµÐºÑÐ° Ñ ÑÑÑÑÐ¾Ð¼ Ð·Ð°Ð½ÑÑÐ¾ÑÑÐ¸ Ð¸ ÑÐ¿ÐµÑÐ¸Ð°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÐ°Ð±Ð¾ÑÐ½Ð¸ÐºÐ¾Ð² Ð² ÐºÐ¾Ð¼Ð°Ð½Ð´Ðµ, ÑÑÐ¾Ð±Ñ Ð¼Ð¾Ð¶Ð½Ð¾ Ð±ÑÐ»Ð¾ Ð¾ÑÐµÐ½Ð¸ÑÑ Ð¿ÑÐ¾ÐµÐºÑ Ð¸ Ð¿Ð¾Ð»ÑÑÐ¸ÑÑ Ð²ÑÐµÐ¼ÐµÐ½Ð½ÑÑ Ð´Ð¸Ð°Ð³ÑÐ°Ð¼Ð¼Ñ. ÐÐ°Ð´Ð°ÑÐ¸, ÐºÐ¾ÑÐ¾ÑÑÐµ ÑÐµÑÐ°Ð»Ð¸ÑÑ Ð² ÑÐ¾Ð´Ðµ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ: 1. ÐÐ¾ÑÑÐ°Ð½Ð¾Ð²ÐºÐ° Ð¸ ÑÐ¾ÑÐ¼Ð°Ð»ÑÐ½Ð¾Ðµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð·Ð°Ð´Ð°ÑÐ¸ ÑÐ°Ð±Ð¾ÑÑ 2. ÐÐ¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð¼ÐµÑÐ¾Ð´Ð¸Ðº Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ 3. ÐÑÐ±Ð¾Ñ Ð¼ÐµÑÐ¾Ð´Ð¸Ðº Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ 4. ÐÐ¿Ð¸ÑÐ°Ð½Ð¸Ðµ Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÑ ÑÑÐµÐ´ÑÑÐ²Ð° Ð´Ð»Ñ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ 5. ÐÑÐ±Ð¾Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾ ÑÑÐµÐºÐ° Ð´Ð»Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ ÑÑÐµÐ´ÑÑÐ²Ð° 6. Ð ÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ ÑÑÐµÐ´ÑÑÐ²Ð° Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ 7. Ð¢ÐµÑÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÑÐµÐ´ÑÑÐ²Ð° ÐÑÐ» Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¼ÐµÑÐ¾Ð´Ð¸Ðº Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ. ÐÐ¾ÑÐ»Ðµ Ð°Ð½Ð°Ð»Ð¸Ð·Ð° Ð±ÑÐ»Ð¸ Ð²ÑÐ±ÑÐ°Ð½Ñ Ð´Ð²Ðµ Ð¼ÐµÑÐ¾Ð´Ð¸ÐºÐ¸, Ð¾Ð´Ð½Ð° Ð¸Ð· ÐºÐ¾ÑÐ¾ÑÑÑ Ð±ÑÐ»Ð° ÑÐµÐ°Ð»Ð¸Ð·Ð¾Ð²Ð°Ð½Ð° Ð² ÑÑÐµÐ´ÑÑÐ²Ðµ Ð¾ÑÐµÐ½ÐºÐ¸ ÑÑÑÐ´Ð¾Ð·Ð°ÑÑÐ°Ñ Ð´Ð»Ñ OC Android.
description: This work is devoted to the development of a tool for estimating labor costs. The paper considers methods for estimating labor costs, an algorithm for constructing a timing diagram for a project, taking into account the employment and specialization of employees in a team, so that you can evaluate the project and get a timing diagram. Tasks that were solved during the study: 1. Statement and formal description of the task of the work 2. Description of the methodology for assessing labor costs 3. Selection of methods for estimating labor costs 4. Description of the architecture of the labor assessment tool 5. Selection of the technological stack for the implementation of the tool 6. Implementation of the labor assessment tool 7. Testing of the received funds The analysis of methods for assessing labor costs was carried out. After the analysis, two methods were selected, one of which was implemented in the labor assessment tool for OC Android.
Faraday Rotation Measure Synthesis for Magnetic Fields of Galaxies
Creators: name: Frick, P.
name: Sokoloff, D.
name: Stepanov, R.
name: Beck, R.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Instrumentation and Methods for Astrophysics (astro-ph.IM)
subject: FOS: Physical sciences

description: RM Synthesis was recently developed as a new tool for the interpretation of polarized emission data in order to separate the contributions of different sources lying on the same line of sight. Until now the method was mainly applied to discrete sources in Faraday space (Faraday screens). Here we consider how to apply RM Synthesis to reconstruct the Faraday dispersion function, aiming at the further extraction of information concerning the magnetic fields of extended sources, e.g. galaxies. The main attention is given to two related novelties in the method, i.e. the symmetry argument in Faraday space and the wavelet technique. We give a relation between our method and the previous applications of RM Synthesis to point-like sources. We demonstrate that the traditional RM Synthesis for a point-like source indirectly implies a symmetry argument and, in this sense, can be considered as a particular case of the method presented here. Investigating the applications of RM Synthesis to polarization details associated with small-scale magnetic fields, we isolate an option which was not covered by the ideas of the Burn theory, i.e. using quantities averaged over small-scale fluctuations of magnetic field and electron density. We describe the contribution of small-scale fields in terms of Faraday dispersion and beam depolarization. We consider the complex polarization for RM Synthesis without any averaging over small-scale fluctuations of magnetic field and electron density and demonstrate that it allows us to isolate the contribution from small-scale field.
description: 10 pages, 12 figures, accepted in MNRAS
title: Analyse et création d'un escape game pédagogique en mathématiques
title: Analyse et création d'un escape game pédagogique en mathématiques
titleType: AlternativeTitle
Creators: name: Studer, Arnaud
name: Petit, Etienne
Publisher: name: Unknown
Year: 0
Subjects: subject: Escape Game
subject: Mathématiques
subject: Jeu sérieux
subject: Gamification
subject: Secondaire II

description: Ce mémoire professionnel propose une base théorique sur l’utilisation du jeu dans l’enseignement, avant de traiter plus en profondeur le cas des jeux de type escape game en mathématiques au niveau secondaire II. Nous y proposons une grille d’analyse prenant en compte différentes caractéristiques que nous considérons essentielles dans l’élaboration de ce type de jeu pour son utilisation en classe. En particulier nous différencions les caractéristiques pédagogiques, ludiques et pratiques. Nous appliquons ensuite cette grille à trois escape games existants disponibles sur le web. Ces analyses nous amènent à la conclusion que si les caractéristiques pédagogiques sont en général assez développées, certaines caractéristiques ludiques comme l’immersion et la narration sont très souvent mises de côté. Enfin nous proposons un escape game original destiné à nos classes de 1ères maturité. Celui-ci se focalisera donc en priorité sur la cohabitation entre immersion narrative et objectifs pédagogiques. Nous appliquons la grille d’analyse à notre création et remarquons que d’autres caractéristiques, notamment la flexibilité, payent le prix du choix de nos priorités. Finalement, nous proposons des pistes d’amélioration à moyen et long terme pour notre jeu.
title: Alberti, Heinrich Christian
title: Catalogus Professorum Halensis
titleType: Subtitle
title: Biografienportal Sachsen-Anhalt
titleType: Other
Creators: name: Catalogus Professorum Halensis
name: Schopferer, Julia
Publisher: name: Historisches Datenzentrum Sachsen-Anhalt,Institut für Landesgeschichte (Sachsen-Anhalt)
Year: 2025
Subjects: subject: History
classificationCode: 4023025-9
subject: Halle (Saale)
valueUri: https://d-nb.info/gnd/4023025-9
classificationCode: 4006804-3
subject: Biografie
valueUri: https://d-nb.info/gnd/4006804-3
classificationCode: 4166546-6
subject: Landesgeschichte
valueUri: https://d-nb.info/gnd/4166546-6
classificationCode: 4051181-9
subject: Sachsen-Anhalt
valueUri: https://d-nb.info/gnd/4051181-9
classificationCode: 1048495779
subject: Universität Halle (Saale) | Halle (Saale)
valueUri: https://d-nb.info/gnd/1048495779
classificationCode: 2024276-1
subject: Martin-Luther-Universität Halle-Wittenberg | Halle (Saale); Wittenberg
valueUri: https://d-nb.info/gnd/2024276-1
classificationCode: 4020517-4
subject: Geschichte
valueUri: https://d-nb.info/gnd/4020517-4
classificationCode: 7504326-9
subject: Universitätsgeschichte
valueUri: https://d-nb.info/gnd/7504326-9
classificationCode: 7504427-4
subject: Wissenschaftsgeschichte
valueUri: https://d-nb.info/gnd/7504427-4
subject: Biografienportal Sachsen-Anhalt
subject: Catalogus Professorum Halensis
classificationCode: 1080911200
subject: Schopferer, Julia | Historikerin
valueUri: https://d-nb.info/gnd/1080911200
classificationCode: 10422486X
subject: Alberti, Heinrich Christian | 1722–1782 | Arzt
valueUri: https://d-nb.info/gnd/10422486X

description: Das Biografienportal Sachsen-Anhalt versammelt in Erst- und Zweitveröffentlichung oder zu Zwecken der Langzeitarchivierung Biografien von Menschen aus und in Sachsen-Anhalt. Integriert wurde der Catalogus Professorum Halensis, der durch Mitarbeitende des Instituts für Geschichte der Martin-Luther-Universität Halle-Wittenberg entstand. Dabei handelt es sich um ein bio-bibliografisches Online-Lexikon zu den Professoren der Universität Halle zwischen 1694 und 1968. Die Texte wurden vor allem von Henrik Eberle und anderen Mitarbeitenden zwischen 2005 und 2010 recherchiert und erstellt. Etliche Artikel zum Zeitraum 1694 bis 1817 verfasste Julia Schopferer. Bei der Überführung in das Biografienportal wurden die Lebensangaben neu recherchiert und Metadaten über Verfahren des Named Entity Recogniton erschlossen. Automatisiert erkannt wurden Personennamen, Ortsbezeichnungen und Körperschaften, die in der hier vorhandenen RTF-Datei indexiert vorliegt. Zudem wurden diese mit GND-Einträgen abgeglichen. Weiterhin erfolgte ein Abgleich mit der „Ontologie der historischen, deutschsprachigen Amts- und Berufsbezeichnungen“. Die Texte liegen im Jahr 2024 in zweifacher Ausgabe im Catalogus Professorum Halensis des Universitätsarchivs und des Biografienportals des Historischen Datenzentrums Sachsen-Anhalts vor. Sie werden hier für die Langzeitarchivierung der ursprünglichen Fassung archiviert.
description: https://www.catalogus-professorum-halensis.de/
description: Biografienportal Sachsen-Anhalt: https://www.histdata.uni-halle.de/
Hydrodynamics of R-charged D1-branes
Creators: name: David, Justin R.
name: Mahato, Manavendra
name: Thakur, Somyadip
name: Wadia, Spenta R.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study the hydrodynamic properties of strongly coupled $SU(N)$ Yang-Mills theory of the D1-brane at finite temperature and at a non-zero density of R-charge in the framework of gauge/gravity duality. The gravity dual description involves a charged black hole solution of an Einstein-Maxwell-dilaton system in 3 dimensions which is obtained by a consistent truncation of the spinning D1-brane in 10 dimensions. We evaluate thermal and electrical conductivity as well as the bulk viscosity as a function of the chemical potential conjugate to the R-charges of the D1-brane. We show that the ratio of bulk viscosity to entropy density is independent of the chemical potential and is equal to $1/4π$. The thermal conductivity and bulk viscosity obey a relationship similar to the Wiedemann-Franz law. We show that at the boundary of thermodynamic stability, the charge diffusion mode becomes unstable and the transport coefficients exhibit critical behaviour. Our method for evaluating the transport coefficients relies on expressing the second order differential equations in terms of a first order equation which dictates the radial evolution of the transport coefficient. The radial evolution equations can be solved exactly for the transport coefficients of our interest. We observe that transport coefficients of the D1-brane theory are related to that of the M2-brane by an overall proportionality constant which sets the dimensions.
description: 57 pages, 12 figures
title: L'impact du stress sur la performance et la mémoire des élèves
title: L'impact du stress sur la performance et la mémoire des élèves
titleType: AlternativeTitle
Creators: name: Pedrelli, Luca
name: Peretti, Nicolas
Publisher: name: Unknown
Year: 0
Subjects: subject: Stress
subject: Mémoire
subject: Performance
subject: Stresseurs
subject: Climat de classe
subject: Coping

description: Dans ce travail, nous tentons d’analyser l’impact que peut avoir le stress psychologique sur les performances cognitives ainsi que la mémoire en situation d’apprentissage. Nous définissons les notions de stress psychologique et de stresseur, décrivons les différents types de mémoire cognitive et ses phases, les concepts de climat de classe, de coping ainsi que le processus du stress pour l’organisme. Nos résultats se penchent sur l’impact du stress sur la mémoire ainsi que la performance en général. Pour se faire, nous effectuons une revue de littérature afin de rassembler les résultats actuels principaux sur cette problématique. Tout d’abord, nous étudions l’impact général que peut avoir un stresseur sur la mémoire. Plus précisément, nous présentons les bénéfices ou les pertes que peut provoquer le stress sur l’encodage, la consolidation, la récupération ou la reconsolidation. Nous exposons ensuite la recherche actuelle faite sur le lien entre stress et performance dans le cadre scolaire et universitaire. Pour se faire, nous nous concentrons sur les intermédiaires de la dépression et du sommeil. Autrement dit, nous étudions les liens qu’ont ces deux éléments avec le stress, et avec la performance. Dans la dernière partie du travail, nous tentons de donner des pistes pour les enseignants afin d’améliorer le cadre de vie et de travail dans leur classe. Nous nous basons sur nos résultats afin de proposer quelques éléments pouvant avoir un impact sur la diminution du stress des élèves en classe. De plus, nous énonçons certains symptômes “scolaires” du stress des élèves qui peuvent être identifiés par les enseignants. Finalement, nous suggérons quelques méthodes pour une meilleure gestion du stress pendant les cours afin d’instaurer un climat de classe favorisant les apprentissages.
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¼Ð¾Ð´ÐµÐ»Ð¸ Ð¸Ð¼Ð¿ÑÐ»ÑÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»Ñ Ð´Ð»Ñ Ð½ÐµÐ¹ÑÐ¾Ð¼Ð¾ÑÑÐ½ÑÑ ÑÐ¸ÑÑÐµÐ¼
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Development of a model of a pulse converter for neuromorphic systems
Creators: name: Ð¡Ð¼Ð¾Ð»ÑÐºÐ¾Ð², ÐÐ²Ð°Ð½
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2021
Subjects: ÐÐµÐ¹ÑÐ¾Ð½Ð½ÑÐµ ÑÐµÑÐ¸
ÐÐ»Ð°ÑÑÐµÑÑ
ÐÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°ÑÐµÐ»Ð¸
Ð½ÐµÐ¹ÑÐ¾Ð½ÐµÑÐµÑÐºÐ¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ð¹ Ð±Ð°Ð·Ð¸Ñ
Ð¼Ð¾Ð´ÐµÐ»Ñ Ð½ÐµÐ¹ÑÐ¾Ð½Ð° ÐÐ¶Ð¸ÐºÐµÐ²Ð¸ÑÐ°
Ð¼ÐµÑ Ð°Ð½Ð¸Ð·Ð¼Ñ Ð»Ð¾ÐºÐ°Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¾Ð±ÑÑÐµÐ½Ð¸Ñ
neuro-fuzzy basis
Izhikevich neuron model
local learning mechanisms

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¾Ð¿Ð¸ÑÐ°Ð½Ð° Ð¼Ð¾Ð´ÐµÐ»Ñ Ð´Ð»Ñ Ð¿ÑÐµÐ¾Ð±ÑÐ°Ð·Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¸Ð¼Ð¿ÑÐ»ÑÑÐ½ÑÑ ÑÐ¸Ð³Ð½Ð°Ð»Ð¾Ð², Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð½Ð°Ñ Ð½Ð° Ð½ÐµÑÑÑÐºÐ¾ Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¾Ð¼ Ð±Ð°Ð·Ð¸ÑÐµ. ÐÑÐµÐ´ÑÑÐ°Ð²Ð»ÐµÐ½Ð° Ð¼Ð¾Ð´ÐµÐ»Ñ Ð¿Ð¾Ð»ÑÑÐµÐ½Ð½Ð¾Ð¹ ÑÐ¸ÑÑÐµÐ¼Ñ Ð¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÑ Ð¼Ð¾Ð´ÐµÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð±Ð¸Ð¾Ð¿Ð¾Ð´Ð¾Ð±Ð½ÑÑ Ð½ÐµÐ¹ÑÐ¾Ð½Ð¾Ð² Ð¸ Ð½ÐµÐ¹ÑÐ¾Ð½Ð½ÑÑ ÑÐµÑÐµÐ¹ Ð´Ð»Ñ Ð·Ð°Ð´Ð°Ñ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ.
description: This paper describes a model for converting pulse signals based on a fuzzy logical basis. A model of the resulting system and the results of modeling biosimilar neurons and neural networks for control tasks are presented.
The size of the nucleosome
Creators: name: Bohr, Jakob
name: Olsen, Kasper
Publisher: name: arXiv
Year: 2011
Subjects: subject: Biological Physics (physics.bio-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: Biomolecules (q-bio.BM)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The structural origin of the size of the 11 nm nucleosomal disc is addressed. On the nanometer length-scale the organization of DNA as chromatin in the chromosomes involves a coiling of DNA around the histone core of the nucleosome. We suggest that the size of the nucleosome core particle is dictated by the fulfillment of two criteria: One is optimizing the volume fraction of the DNA double helix; this requirement for close-packing has its root in optimizing atomic and molecular interactions. The other criterion being that of having a zero strain-twist coupling; being a zero-twist structure is a necessity when allowing for transient tensile stresses during the reorganization of DNA, e.g., during the reposition, or sliding, of a nucleosome along the DNA double helix. The mathematical model we apply is based on a tubular description of double helices assuming hard walls. When the base-pairs of the linker-DNA is included the estimate of the size of an ideal nucleosome is in close agreement with the experimental numbers. Interestingly, the size of the nucleosome is shown to be a consequence of intrinsic properties of the DNA double helix.
description: 11 pages, 5 figures; v2: minor modifications
Resistance of reinforced concrete cantilever shear walls to seismic shear demands
Creators: name: Young, Mitchell P.
Publisher: name: University of British Columbia
Year: 2019

description: Reinforced concrete shear wall core structures are very common among high-rise buildings in Vancouver, and increasingly so elsewhere. While the flexural behaviour of these structures is well understood, the shear behaviour is not. Much of the research regarding the shear behaviour is related to the amplifications of demands due to higher mode seismic shear, however, there has been little research regarding the resistance of these structures to higher mode seismic shear demands. It is theorized that due to the lack of experimental data on which more complex shear models could be based on, structural engineers have resorted to using building models with complex non-linear fibre section flexural stiffness, but a linear elastic shear stiffness. Which may have lead to higher mode shear demands to be overestimated. Therefore, the goal of this thesis is to complete an experimental program in which scaled shear wall core specimens are tested under higher mode demands in the cantilevered direction. Through the experimental program, topics that are investigated include: the effect of the rate of loading on the shear resistance, the effect of existing flexural base yielding on the shear resistance, and the presence of a plastic hinge at the base on the shear resistance. In addition to the experimental program, a series of dynamic analyses were completed on a simplified model, in order to better understand the behaviour of a high-rise reinforced concrete shear wall structure to higher mode effects, and the results of the experimental program are also compared to predictions made using common analytical tools.
MHD models of Pulsar Wind Nebulae
Creators: name: Bucciantini, N.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Pulsar Wind Nebulae (PWNe) are bubbles or relativistic plasma that form when the pulsar wind is confined by the SNR or the ISM. Recent observations have shown a richness of emission features that has driven a renewed interest in the theoretical modeling of these objects. In recent years a MHD paradigm has been developed, capable of reproducing almost all of the observed properties of PWNe, shedding new light on many old issues. Given that PWNe are perhaps the nearest systems where processes related to relativistic dynamics can be investigated with high accuracy, a reliable model of their behavior is paramount for a correct understanding of high energy astrophysics in general. I will review the present status of MHD models: what are the key ingredients, their successes, and open questions that still need further investigation.
description: 18 pages, 5 figures, Invited Review, Proceedings of the "ICREA Workshop on The High-Energy Emission from Pulsars and their Systems", Sant Cugat, Spain, April 12-16, 2010
title: The concept of happiness in Kant's moral, legal and political philosophy
Creators: name: Pinheiro Walla, Alice
Publisher: name: University of St Andrews
publisherIdentifier: https://ror.org/02wn5qz54
publisherIdentifierScheme: ROR
Year: 2012

description: This doctoral thesis analyzes the systematic role of Kant’s conception of happiness in his moral, legal and political theory. Although many of his conclusions and arguments are directly or indirectly influenced by his conception of human happiness, Kant’s underlying assumptions are rarely overtly discussed or given much detail in his works. Kant also provides different and apparently incompatible definitions of happiness. This research explores the domains of Kant’s practical philosophy in which his conception of happiness plays a systematic role: the relation between the natural need of human beings to pursue happiness and the ends-oriented structure of the human will; Kant’s anti-eudaimonism in ethical theory; Kant’s claim that we have an indirect duty to promote our own happiness and the problem that under certain circumstances, the indeterminacy of happiness makes it not irrational to choose short term satisfaction at the costs of one’s overall, long term happiness, given Kant’s conception of non-moral choice as expectation of pleasure; Kant’s justification of the duty to adopt the happiness of others as our ends (the duty of beneficence) and the latitude and eventual demandingness of this duty; finally, since Kant also subsumes subsistence needs and welfare under the concept of happiness of individuals, I also engage with the question of state provision for the poor in the Kantian Rechtsstaat and explore Kant’s conception of equity or fairness (Billigkeit) as an alternative to the traditional minimalist and the welfare interpretations of the Kantian state.
A New 626 s Periodic X-ray Source in the Direction of the Galactic Center
Creators: name: Farrell, Sean A.
name: Gosling, Andrew J.
name: Webb, Natalie A.
name: Barret, Didier
name: Rosen, Simon R.
name: Sakano, Masaaki
name: Pancrazi, Benoit
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Here we report the detection of a 626 s periodic modulation from the X-ray source 2XMM J174016.0-290337 located in the direction of the Galactic center. We present temporal and spectral analyses of archival XMM-Newton data and photometry of archived near-infrared data in order to investigate the nature of this source. We find that the X-ray light curve shows a strong modulation at 626 +/- 2 s with a confidence level > 99.9% and a pulsed fraction of 54%. Spectral fitting demonstrates that the spectrum is consistent with an absorbed power law. No significant spectral variability was observed over the 626 s period. We have investigated the possibility that the 626 s period is orbital in nature (either that of an ultra-compact X-ray binary or an AM CVn) or related to the spin of a compact object (either an accretion powered pulsar or an intermediate polar). The X-ray properties of the source and the photometry of the candidate near-infrared counterparts are consistent with an accreting neutron star X-ray binary on the near-side of the Galactic bulge, where the 626 s period is most likely indicative of the pulsar spin period. However, we cannot rule out an ultra-compact X-ray binary or an intermediate polar with the data at hand. In the former case, if the 626 s modulation is the orbital period of an X-ray binary, it would be the shortest period system known. In the latter case, the modulation would be the spin period of a magnetic white dwarf. However, we find no evidence for absorption dips over the 626 s period, a low temperature black body spectral component, or Fe Kalpha emission lines. These features are commonly observed in intermediate polars, making 2XMM J174016.0-290337 a rather unusual member of this class if confirmed. We instead suggest that 2XMM J174016.0-290337 could be a new addition to the emerging class of symbiotic X-ray binaries.
description: 11 pages, 10 figures, submitted to A&A on 18th January 2010, accepted for publication 20th August 2010
Rigid Analytic Quantum Groups
Creators: name: Dupré, Nicolas
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Quantum groups
D-modules
p-adic representation theory

description: Following constructions in rigid analytic geometry, we introduce a theory of $p$-adic analytic quantum groups. We first define Fréchet completions $\wideparen{U_q(\mathfrak{g})}$ and $\wideparen{\mathcal{O}_q(G)}$ of the quantized enveloping algebra of a semisimple Lie algebra $\mathfrak{g}$ and the quantized coordinate ring of the corresponding semisimple algebraic group $G$ respectively. We consider these to be quantum analogues of the Arens-Michael envelope of the enveloping algebra $U(\mathfrak{g})$ and of the algebra of rigid analytic functions on the rigid analytification of $G$ respectively. We show that these algebras are topological Hopf algebras and, by adapting techniques extracted from work of Ardakov-Wadsley, Schmidt and Emerton in $p$-adic representation theory, we also show that they are Fréchet-Stein algebras and use this to investigate an analogue of category $\mathcal{O}$ for $\wideparen{U_q(\mathfrak{g})}$. We then introduce a $p$-adic analytic analogue of Backelin and Kremnizer's construction of the quantum flag variety of a semisimple algebraic group, using a Banach completion of $\wideparen{\mathcal{O}_q(G)}$. Our main result is a Beilinson-Bernstein localisation theorem in this context. We define a category of $\lambda$-twisted $D$-modules on this analytic quantum flag variety. This category has a distinguished object $\widehat{\D_q^\lambda}$ which plays the role of the sheaf of $\lambda$-twisted differential operators. We show that when $\lambda$ is regular and dominant, the global section functor gives an equivalence of categories between the coherent $\lambda$-twisted $D$-modules and the finitely presented modules over the global sections of $\widehat{\mathcal{D}_q^\lambda}$. The construction of this analytic quantum flag variety involves working with Banach comodules over the Banach completion $\OqBhat$ of the quantum coordinate algebra of the Borel. Along the way, we also show that Banach comodules over $\OqBhat$ can be naturally identified with what we call topologically integrable modules over the Banach completion of Lusztig's integral form of the quantum Borel.
title: Théories et pratiques libertaires en éducation : Quelle place pour l'anarchisme dans l'école publique ?
title: Théories et pratiques libertaires en éducation : Quelle place pour l'anarchisme dans l'école publique ?
titleType: AlternativeTitle
Creators: name: Pamingle, Lucien
Publisher: name: Unknown
Year: 0
Subjects: subject: anarchisme
subject: éducation
subject: pédagogie libertaire
subject: école publique
subject: critique de l’école
subject: éducation intégrale
subject: pédagogie intersectionnelle
subject: Sébastien Faure
subject: Paul Robin
subject: Francisco Ferrer
subject: Lev Vygotski
subject: Lorin Anderson
subject: David Krathwohl
subject: John Hattie

description: Ce travail s’intéresse aux théories et aux pratiques anarchistes dans le domaine de l’éducation et vise à reconsidérer la place de l’anarchisme dans les écoles publiques. Ces idéaux libertaires sont confrontés aux théories éducatives actuellement enseignées dans les écoles pédagogiques. Un bref panorama des expériences éducatives anarchistes est dressé et fait le lien entre la théorie et la pratique. À travers une approche socio-historique, nous tenterons de comprendre les évolutions de la pensée anarchiste et son ouverture aux nouveaux défis socioéconomiques ainsi qu’aux théories postmodernes. Quelques pistes d’activités et de stratégies « anarchistes » sont proposées en concordance avec les plans d’études et les théories éducatives actuelles. L’idée est d’ouvrir un dialogue entre ces deux types de pédagogies qui pourrait s’avérer fructueux pour la pensée anarchiste, tout en évitant la récupération des pratiques libertaires à des fins d’efficacité des apprentissages au service de l’État et des milieux patronaux. Car il ne faut pas oublier que la pédagogie anarchiste est profondément enracinée dans un désir d’émancipation, de liberté et d’égalité.
Jets in QCD media: from color coherence to decoherence
Creators: name: Mehtar-Tani, Y.
name: Salgado, C. A.
name: Tywoniuk, K.
Publisher: name: arXiv
Year: 2011
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We investigate soft gluon radiation off a quark-antiquark antenna in both color singlet and octet configurations traversing a dense medium. We demonstrate that, in both cases, multiple scatterings lead to a gradual decoherence of the antenna radiation as a function of the medium density. In particular, in the limit of an completely opaque medium, total decoherence is obtained, i.e., the quark and the antiquark radiate as independent emitters in vacuum, thus losing memory of their origin. We comment on possible implications on intrajet observables in heavy-ion collisions.
description: 4 pages, 1 figure
Identification of rolling resistance as a shape parameter in sheared granular media
Creators: name: Estrada, Nicolas
name: Azema, Émilien
name: Radjaï, Farhang
name: Taboada, Alfredo
Publisher: name: arXiv
Year: 2011
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Using contact dynamics simulations, we compare the effect of rolling resistance at the contacts in granular systems composed of disks with the effect of angularity in granular systems composed of regular polygonal particles. In simple shear conditions, we consider four aspects of the mechanical behavior of these systems in the steady state: shear strength, solid fraction, force and fabric anisotropies, and probability distribution of contact forces. Our main finding is that, based on the energy dissipation associated with relative rotation between two particles in contact, the effect of rolling resistance can explicitly be identified with that of the number of sides in a regular polygonal particle. This finding supports the use of rolling resistance as a shape parameter accounting for particle angularity and shows unambiguously that one of the main influencing factors behind the mechanical behavior of granular systems composed of noncircular particles is the partial hindrance of rotations as a result of angular particle shape.
description: Soumis a Physical Review E; Statistical, Nonlinear, and Soft Matter Physics http://link.aps.org/doi/10.1103/PhysRevE.84.011306
Characterizing labile protons by NMR spectroscopy
Creators: name: Brockerman, Jacob Arthur
Publisher: name: University of British Columbia
Year: 2019

description: Labile hydrogens in proteins, including those on ionizable functional groups, undergo rapid exchange with water and thus are typically difficult to characterize by current techniques in structural biology. Their properties are often inferred from biophysical arguments rather than direct experimental determination. Here I present new methods for studying these hydrogens by NMR spectroscopy using two glycoside hydrolases as model protein systems. Chapter 2 centres on characterizing the hydroxyl protons of serine and threonine residues in proteins by NMR spectroscopy. Using auxtrophic E. coli strains, I produced Bacillus circulans xylanase (BcX) selectively labeled with ¹³C/¹⁵N-serine or ¹³C/¹⁵N-threonine. Signals from two serine and three threonine hydroxyls in these protein samples were readily observed using long-range heteronuclear scalar correlation experiments. Their dihedral angle-dependent scalar couplings with adjacent sidechain protons were determined via a quantitative ¹³C/1¹⁵N-filtered spin-echo difference experiment. The hydrogen exchange kinetics of these hydroxyls were measured using a ¹³C/¹⁵N-filtered CLEANEX-PM pulse sequence. Collectively, these experiments provided insights into the structural and dynamic properties of this model protein. Chapter 3 characterizes a mutant of T4 phage lysozyme (T4L) with an altered catalytic mechanism due to the substitution of residue Thr26 with a histidine (T26H). It has been proposed that T26H-T4L hydrolyzes peptidoglycan via a double displacement mechanism with His26 serving the unusual role of a nucleophile. To gain further insights into this or alternative mechanisms, I used NMR spectroscopy to measure the acid dissociation constants (pKa values) and/or ionization states of all the Asp, Glu, His, and Arg residues in the T4L mutant. Most notably, the pKa value of the proposed nucleophile His26 is 6.8 ± 0.1, whereas that of the general acid Glu11 is 4.7 ± 0.1. If the proposed mechanism holds true, then T26H-T4L follows a reverse protonation pathway where only a minor population of protein is in its catalytically competent ionization state (His26 deprotonated and Glu11 protonated). I also demonstrated that all arginines in T26H-T4L, including the active site Arg145, are positively charged under neutral pH. This stands in contrast to a recent neutron crystallographic study of T26H-T4L in which, perplexingly, Arg145 was proposed to have a deprotonated guanidine sidechain.
RXTE observations of the 1A 1118-61 in an outburst, and the discovery of a cyclotron line
Creators: name: Doroshenko, V.
name: Suchy, S.
name: Santangelo, A.
name: Staubert, R.
name: Kreykenbohm, I.
name: Rothschild, R.
name: Pottschmidt, K.
name: Wilms, J.
Publisher: name: arXiv
Year: 2010
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present the analysis of RXTE monitoring data obtained during the January 2009 outburst of the hard X-ray transient 1A 1118-61. Using these observations the broadband (3.5-120 keV) spectrum of the source was measured for the first time ever. We have found that the broadband continuum spectrum of the source is similar to other accreting pulsars and is well described by several conventionally used phenomenological models. We have discovered that regardless of the applied continuum model, a prominent broad absorption feature at ~55 keV is observed. We interpret this feature as a cyclotron resonance scattering feature (CRSF). The observed CRSF energy is one of the highest known and corresponds to a magnetic field of B~4.8 x 10^12 G in the scattering region. Our data also indicate the presence of an iron emission line presence that has not been previously reported for 1A 1118-61. Timing properties of the source, including a strong spin-up, were found to be similar to those observed by CGRO/BATSE during the previous outburst, but the broadband capabilities of RXTE reveal a more complicated energy dependency of the pulse-profile.
description: 5 pages, 5 figures