cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Nickel(II) complexes of ONS donor Schiff base ligands: synthesis, combined DFT-experimental characterization, redox, thermal, and in vitro biological investigation
Creators: name: R.C. Maurya
name: B.A. Malik
name: J.M. Mir
name: P.K. Vishwakarma
name: D.K. Rajak
name: N. Jain
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry
subject: Biophysics

description: This article reports the synthesis and characterization of four Ni(II) Schiff base complexes, [Ni(L)(H2O)], where H2L = N-(dehydroacetic acid)-thiosemicarbazide (H2dha-tsc), N-(dehydroacetic acid)-4-methyl-3-thiosemicarbazide (H2dha-mtsc), N-(dehydroacetic acid)-4-phenyl-3-thiosemicarbazide (H2dha-ptsc), or N-(dehydroacetic acid)-4-phenylsemicarbazide (H2dha-psc). The nature of bonding and stereochemistry of these complexes have been deduced from elemental analysis, infrared and electronic spectral studies, molar conductance, magnetic measurements, mass spectrometry, thermogravimetric analysis, 1H NMR and 13C NMR studies, and cyclic voltammetry. The stabilities of the complexes were determined in both solid state and solution. Molecular geometry optimizations and vibrational frequency calculations were performed with Gaussian 09 software package using density functional theory (DFT) with B3LYP/6-311G for a ligand (dha-ptscH2) and B3LYP/LANL2DZ combination for [Ni(dha-mtsc)(H2O)]. Based on the combined experimental and theoretical studies, square planar geometry has been proposed for the Ni(II) complexes. The Schiff base ligands and their metal complexes were screened for antibacterial activities against gram-negative bacteria (Escherichia coli ) at different concentrations to get their minimum inhibition concentration values. The bactericidal activity was enhanced in metal complexes as compared to free ligands.
Nickel(II) complexes of ONS donor Schiff base ligands: Synthesis, combined DFT-experimental characterization, redox, thermal and in vitro biological investigation
Creators: name: R.C. Maurya
name: B.A. Malik
name: J.M. Mir
name: P.K. Vishwakarma
name: D.K. Rajak
name: N. Jain
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Cancer
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Microbiology
subject: FOS: Biological sciences
subject: Biochemistry
subject: Biophysics

description: This paper reports the synthesis and characterization of four Ni(II) Schiff base complexes, [Ni(L)(H2O)], where H2L = N-(dehydroacetic acid)-thiosemicarbazide (H2dha-tsc), N-(dehydroacetic acid)-4-methyl-3-thiosemicarbazide (H2dha-mtsc), N-(dehydroacetic acid)-4-phenyl-3-thiosemicarbazide (H2dha-ptsc), or N-(dehydroacetic acid)-4-phenylsemicarbazide (H2dha-psc). The nature of bonding and stereochemistry of these complexes have been deduced from elemental analysis, infrared and electronic spectral studies, molar conductance, magnetic measurements, mass spectrometry, thermogravimetric analysis, 1H-NMR and 13C-NMR studies and cyclic voltammetry. The stabilities of the complexes were determined in both solid state and solution. Molecular geometry optimizations and vibrational frequency calculations were performed with Gaussian 09 software package by using density functional theory (DFT) with B3LYP/6-311G for a ligand (dha-ptscH2) and B3LYP/LANL2DZ combination for [Ni(dha-mtsc)(H2O)]. Based on the combined experimental and theoretical studies, square planar geometry has been proposed for the Ni(II) complexes. The Schiff base ligands and their metal complexes were screened for antibacterial activities against gram-negative bacteria (E. coli) at different concentrations to get their minimum inhibition concentration (MIC) values. The bactericidal activity was enhanced in metal complexes as compared to free ligands.
Relating gold nanostar shape to function: a study on the applicability of nanostars for photothermal therapy and cellular uptake
Creators: name: Morton, William
Publisher: name: Imperial College London
Year: 2023

description: The following thesis presents a study on gold nanostars, focusing on their geometric properties, characterisation, and applications for photothermal therapy. In this application, the nanostar geometry is crucial for optimising optical properties, specifically the localised surface plasmon resonance and absorption cross-section, which can result in the particle heating when exposed to light. If the nanostar can enter a tumour, it could thermally ablate the cancerous region. However, a fundamental challenge in nanostar characterisation is accurately estimating geometric properties such as particle volume, surface area, and the number of tips. The errors in estimation using Transmission Electron Microscopy (TEM) are first investigated through an analytical investigation, for which a library of 6000 nanostars was created. A statistical analysis suggests that current methods overestimate nanostar volumes, creating discrepancies across studies. A novel method is developed to address this shortcoming by combining Ultraviolet-visible spectroscopy (UV-Vis), TEM images, and Discrete Dipole Approximation (DDA) to characterise nanostar geometry more precisely. Once the geometry is predicted, the absorption cross-section can then be estimated using DDA. Understanding the interaction between nanostars and cell membranes is crucial to understanding their potential use as therapeutics. A molecular dynamics method was reparametrized to better represent the binding limitations of ligands and receptors. Nanostar endocytosis was then studied, assuming cellular uptake is driven by these ligand receptor bonds. By controlling the distribution of nanostar tips the uptake speed can not only be tuned, but wholly inhibited by specific cell types, revolutionising the potential for targeted cell delivery. In conclusion, this thesis offers a unifying method for estimating nanostar geometry, and suggests optimal geometric factors for cell targeting. While the benefits of gold nanostars as photothermal therapeutics are highlighted, I propose that the field instead capitalises on advancements in ligand and protein design for controlling cellular processes through nanoparticle surface interactions.
FRAXIFAM: Reconstructing gene family evolution in the ash genus (Fraxinus).
Creators: name: Cooper, Endymion
Publisher: name: figshare
Year: 2015
Subjects: subject: Botany
subject: Computational Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology

description: Proposal for a Marie Skłodowska-Curie Individual Fellowship. This application was submitted in September 2014 for funding under the first round of Horizon 2020 Framework. This application was successful and the fellowship commenced on the 1st of July 2015. For further information please contact the author via email: endymion.dante.cooper@gmail.com Note that posting this proposal is a personal experiment in Open Science. I ask, therefore, that if this proposal is useful to you, that you make an appropriate acknowledgement (e.g. cite as recommended above) and please let me know by making a comment below!
Replication plan for investment model at national and European level
Creators: name: Materalia
Publisher: name: Zenodo
Year: 2024

description: The initial replication plan for the InvestCEC model provides a foundational framework for adaptation in various urban and regional contexts, with an emphasis on iterative refinement through partner feedback and practical experience. It aims to evolve into a detailed guide that addresses local specifics, thereby facilitating the model's application in diverse settings.
title: Barriers in Participative Water Governance: A Critical Analysis of Community Development Approaches
Creators: name: Shunglu, Raghav
name: Köpke, Sören
name: Kanoi, Lav
name: Nissanka, Thushantha S.
name: Withanachchi, Chandana Rohana
name: Gamage, Deepika U.
name: Dissanayake, Hansani R.
name: Kibaroglu, Aysegul
name: Ünver, Olcay
name: Withanachchi, Sisira Saddhamangala
Publisher: name: Universität Kassel
Year: 2022
Subjects: subject: social trust
subject: community-based water management projects (CBWM)
subject: climate change
subject: micro-political dynamics
subject: common-pool resources
subject: exit strategy
subject: India
subject: Turkey
subject: Sri Lanka
subject: 320
subject: Indien
subject: Türkei
subject: Sri Lanka
subject: Vertrauen
subject: Wasserwirtschaft
subject: Klimaänderung
subject: Mikropolitik

description: Gefördert durch den Publikationsfonds der Universität Kassel
26 июня – Международный день борьбы с наркоманией: Постер
Creators: name: Берковский Алексей Сергеевич
name: Белоцерковский Юрий Иванович
name: Сергеевич, Шевченко Александр
Publisher: name: Zenodo
Year: 2001
Subjects: ВИЧ/СПИД
Международный день борьбы с наркоманией
HIV/AIDS
International Day Against Drug Abuse and Illicit Trafficking

description: На русском: [26 июня – Международный день борьбы с наркоманией : Постер / разработано Берковский А.С., Белоцерковский Ю.И., Шевченко А.С.; БФ "Червона стрічка", ХОЦПБС // Червона стрічка: Журнал для медицинских работников и СПИД-сервисных организаций, том 4, № 2. – Харьков: УРИС пр. "Создание информационных центров по ВИЧ/СПИДу в Украине", 2001. – С. 49. https://doi.org/10.5281/zenodo.3756219] Постер о Международном дне борьбы с наркоманией входит в число просветительских материалов, разработанных сотрудниками БФ "Червона стрічка" и Харьковского областного центра профилактики и борьбы со СПИДом в рамках проекта "Создание информационных центров по профилактике ВИЧ/СПИДа в Украине", реализованного при финансовой поддержке "Врачей без границ" (Голландия) в 2000-2001 гг. украино-российской информационной сетью СПИД-сервисных организаций. Ключевые слова: ВИЧ/СПИД, Международный день борьбы с наркоманией. In English: [June 26 – International Day Against Drug Abuse and Illicit Trafficking : Poster / dev. Berkovsky A.S., Belotserkovsky Yu.I., Shevchenko A.S.; CF "Red Ribbon", KhRCPFA // Red Ribbon: Journal for medical workers and AIDS service organizations, Vol. 4, No.2. – Kharkov: URIN pr. "Creation of HIV/AIDS Information Centers in Ukraine", 2001. – P. 49. (rus.) https://doi.org/10.5281/zenodo.3756219] Poster about International Day Against Drug Abuse and Illicit Trafficking is one of the educational materials developed by employees of Charity Foundation "Red Ribbon" and the Kharkiv Regional Center for AIDS Prevention and Control as part of the project "Creating Information Centers of HIV/AIDS Prevention in Ukraine", implemented under financial support from Doctors Without Borders (Holland) / Médecins Sans Frontières in 2000-2001 Ukrainian-Russian information network of AIDS service organizations. Keywords: HIV/AIDS, International Day Against Drug Abuse and Illicit Trafficking.
title: Динамика правового регулирования предоставления и использования материнского (семейного) капитала
Creators: name: Безус, Наталья
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2022

description: В статье рассматривают изменения, произошедшие в нормативном регулировании государственной программы по предоставлению материнского (семейного) капитала (далее – МСК). Автор отмечает расширение круга субъектов – получателей материнского капитала, увеличение целевых возможностей его использования, оптимизацию процедуры беззаявительного получения сертификата в электронной форме. В статье формируются предложения по обеспечению доступности данной социальной поддержки через расширение направлений его использования и повышение мер административной и уголовной ответственности недобросовестных родителей.
Draft genome sequence of Rhodococcus erythropolis NSX2, an actinobacterium isolated from a cadmiumcontaminated environment
Creators: name: Egidi, Eleonora
name: Wood, Jen
name: Fox, Edward M.
name: Liu, Wuxing
name: Franks, Ashley E.
Publisher: name: Swinburne
Year: 2024

description: Rhodococcus erythropolis NSX2 is a rhizobacterium isolated from a heavy metal-contaminated environment. The 6.2-Mb annotated genome sequence shows that this strain harbors genes associated with heavy-metal resistance and xenobiotics degradation.
Videogame "Pitanga Town" in the fight against dengue in Costa Rica
Creators: name: Repositorio Academico UPC
name: Zamora, Antón
name: Galán Rodas, Edén
name: Ramírez, Eduardo
name: Rodríguez Morales, Alfonso J.
name: Mayta Tristán, Percy
Publisher: name: figshare
Year: 2015
Subjects: Medicine

description: Una de las prioridades en salud pública a nivel global es el control de las enfermedades transmitidas por vectores, como el dengue, la malaria, la enfermedad de Chagas, la leishmaniasis, la bartonelosis, entre otras. El dengue es una enfermedad viral transmitida por la picadura de las especies del mosquito Aedes, cuya incidencia global se ha incrementado rápidamente en las últimas décadas, estimándose que causa alrededor de 230 millones de infecciones cada año, de los cuales 25 000 son mortales, localizándose principalmente en regiones tropicales y subtropicales (1). La región de las Américas, durante el año 2013, tuvo el mayor reporte histórico de casos, con más de 2,3 millones de casos notificados por los países.
Draft genome sequence of Bacillus cereus LCR12, a plant growth-promoting rhizobacterium isolated from a heavy metal- contaminated environment
Creators: name: Egidi, Eleonora
name: Wood, Jen
name: Mathews, Elizabeth
name: Fox, Edward
name: Liu, Wuxing
name: Franks, Ashley E.
Publisher: name: Swinburne
Year: 2024

description: Bacillus cereus LCR12 is a plant growth-promoting rhizobacterium, isolated from a heavy metal-contaminated environment. The 6.01-Mb annotated genome sequence provides the genetic basis for revealing its potential application to remediate contaminated soils in association with plants.
ОЧИСТКИ ПРОМЫШЛЕННЫХ СТОЧНЫХ ВОД ПОЛИФУНКЦИОНАЛЬНИМИ КОМПОЗИЦИЯМИ
Creators: name: Яхшиева, Ю.Р.
name: Журакулов, Р.Ш.
Publisher: name: Zenodo
Year: 2024

description: Основной целью очистки сточных вод промышленных предприятий является снижение нагрузки на городские очистные сооружения и экономия средств и ресурсов самого предприятия. По поручению Председателя Правления АО «Узбекнефтегаз» осуществляется очистка и использование сточных вод, образующихся на предприятиях, до максимально возможного уровня повторного использования. В результате реализации этих мер можно добиться снижения негативного воздействия на природу, повысить экономическую эффективность и рационального использования водных ресурсов.
Common filamentous Trichoderma asperellum for effective removal of triphenylmethane dyes
Creators: name: Sze Ying Chew
name: Ting, Adeline Su Yien
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: Cancer

description: The dye-removal potential of a common environmental isolate Trichoderma asperellum on four triphenylmethane dyes was studied via biosorption experiments using free-cells and alginate-immobilized forms. T. asperellum demonstrated potential to remove TPM dyes, with higher efficiency when alginate-immobilized forms were used compared to free-cells. Amount of crystal violet (CV), methyl violet (MV), cotton blue (CB), and malachite green (MG) adsorbed by immobilized forms were 60.64, 50.29, 49.91, and 16.61 mg g−1 compared to 12.97, 12.54, 14.34, and 11.44 mg g−1 by free-cells, respectively. Enhanced dye removals by alginate-immobilized T. asperellum were attributed to the carboxyl and hydroxyl functional groups present on the surface of alginate. For free-cells, their surface comprises amine and alkane groups which were less effective in binding dyes. This study is the first to report the dye-removal potential of T. asperellum for triphenylmethane dyes, and we recommend immobilized forms as suitable for application.
THE CONFLICT BETWEEN MOROCCO AND THE POLISARIO OVER THE WESTERN SAHARA
Creators: name: Dr. LUMA SULTAN FARHAN RAWASHDEH
Publisher: name: Zenodo
Year: 2025
Subjects: Conflict, Morocco, The Polisario, Western Sahara.

description: Abstract

This study focuses on examining the Moroccan conflict with the Polisario over Western Sahara, in the absence of a settlement and commitment to a ceasefire. The study proposes a draft peace agreement between Morocco and the Polisario, especially after 50 years of conflict and 8 years of proposals without reaching a political solution that satisfies the parties. By using a descriptive-analytical approach with models and methodological tools, the conflict was analyzed from different perspectives. What the study presents is the result of the optimal solution for resolving the conflict, which is expanded autonomy, and reaching a common ground that eliminates or reduces the disparities between the conflicting parties.
Common filamentous Trichoderma asperellum for effective removal of triphenylmethane dyes
Creators: name: Sze Ying Chew
name: Ting, Adeline Su Yien
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Biotechnology
subject: Cancer

description: The dye-removal potential of a common environmental isolate Trichoderma asperellum on four triphenylmethane dyes was studied via biosorption experiments using free-cells and alginate-immobilized forms. T. asperellum demonstrated potential to remove TPM dyes, with higher efficiency when alginate-immobilized forms were used compared to free-cells. Amount of crystal violet (CV), methyl violet (MV), cotton blue (CB), and malachite green (MG) adsorbed by immobilized forms were 60.64, 50.29, 49.91, and 16.61 mg g−1 compared to 12.97, 12.54, 14.34, and 11.44 mg g−1 by free-cells, respectively. Enhanced dye removals by alginate-immobilized T. asperellum were attributed to the carboxyl and hydroxyl functional groups present on the surface of alginate. For free-cells, their surface comprises amine and alkane groups which were less effective in binding dyes. This study is the first to report the dye-removal potential of T. asperellum for triphenylmethane dyes, and we recommend immobilized forms as suitable for application.
Change-Based Refactoring Mining
Creators: name: Soetens, Quinten
name: Pérez, Javier
name: Demeyer, Serge
Publisher: name: figshare
Year: 2015
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences
subject: Computer Software

description: This short position paper was presented at the International Workshop on Refactoring and Testing (RefTest) June 2013.
Microbial community dynamics in the rhizosphere of a cadmium hyper-accumulator
Creators: name: Wood, Jen
name: Zhang, C.
name: Mathews, E. R.
name: Tang, C.
name: Franks, A. E.
Publisher: name: Swinburne
Year: 2024

description: Phytoextraction is influenced by the indigenous soil microbial communities during the remediation of heavy metal contaminated soils. Soil microbial communities can affect plant growth, metal availability and the performance of phytoextraction-assisting inocula. Understanding the basic ecology of indigenous soil communities associated with the phytoextraction process, including the interplay between selective pressures upon the communities, is an important step towards phytoextraction optimization. This study investigated the impact of cadmium (Cd), and the presence of a Cd-accumulating plant, Carpobrotus rossii (Haw.) Schwantes, on the structure of soil-bacterial and fungal communities using automated ribosomal intergenic spacer analysis (ARISA) and quantitative PCR (qPCR). Whilst Cd had no detectable influence upon fungal communities, bacterial communities underwent significant structural changes with no reduction in 16S rRNA copy number. The presence of C. rossii influenced the structure of all communities and increased ITS copy number. Suites of operational taxonomic units (OTUs) changed in abundance in response to either Cd or C. rossii, however we found little evidence to suggest that the two selective pressures were acting synergistically. The Cd-induced turnover in bacterial OTUs suggests that Cd alters competition dynamics within the community. Further work to understand how competition is altered could provide a deeper understanding of the microbiome-plant-environment and aid phytoextraction optimization.
Competitive traits are more important than stress-tolerance traits in a cadmium-contaminated rhizosphere: A role for trait theory in microbial ecology
Creators: name: Wood, Jen
name: Tang, Caixian
name: Franks, Ashley E.
Publisher: name: Swinburne
Year: 2024

description: Understanding how biotic and abiotic factors govern the assembly of rhizosphere-microbial communities is a long-standing goal in microbial ecology. In phytoremediation research, where plants are used to remediate heavy metal-contaminated soils, a deeper understanding of rhizosphere-microbial ecology is needed to fully exploit the potential of microbial-assisted phytoremediation. This study investigated whether Grime's competitor/stress-tolerator/ruderal (CSR) theory could be used to describe the impact of cadmium (Cd) and the presence of a Cd-accumulating plant, Carpobrotus rossii (Haw.) Schwantes, on the assembly of soil-bacterial communities using Illumina 16S rRNA profiling and the predictive metagenomic-profiling program, PICRUSt. Using predictions based on CSR theory, we hypothesized that Cd and the presence of a rhizosphere would affect community assembly. We predicted that the additional resource availability in the rhizosphere would enrich for competitive life strategists, while the presence of Cd would select for stress-tolerators. Traits identified as competitive followed CSR predictions, discriminating between rhizosphere and bulk-soil communities whilst stress-tolerance traits increased with Cd dose, but only in bulk-soil communities. These findings suggest that a bacterium's competitive attributes are critical to its ability to occupy and proliferate in a Cd-contaminated rhizosphere. Ruderal traits, which relate to community re-colonization potential, were synergistically decreased by the presence of the rhizosphere and Cd dose. Taken together this microcosm study suggests that the CSR theory is broadly applicable to microbial communities. Further work toward developing a simplified and robust strategy for microbial CSR classification will provide an ecologically meaningful framework to interpret community-level changes across a range of biomes.
Development of Calcium-sensing receptor (CaSR) positive allosteric modulators for the treatment of CaSR-related disorders
Creators: name: DINH, LE TUONG VI
Publisher: name: Monash University
Year: 2024
Subjects: classificationCode: 340503
subject: Organic chemical synthesis

description: The calcium-sensing receptor, ubiquitously expressed in the body, is an important target endocrine and calcium handling disorders such as hyperparathyroidism. Current therapeutics for hyperparathyroidism and related disorders are often accompanied by undesirable side effects, which limit their clinical utility. Therefore, there is a need for better therapeutics targeting the CaSR. As the CaSR continues to find application in other diseases, developing tool compounds for the receptor to better design drug molecules become crucial. Hence, this study endeavours to gain better insights by probing the CaSR with tool compounds and focuses on developing new therapeutic candidates targeting the CaSR.
Change-Based Refactoring Minign
Creators: name: Soetens, Quinten
name: Pérez, Javier
name: Demeyer, Serge
Publisher: name: figshare
Year: 2015
Subjects: subject: 80309 Software Engineering
subject: FOS: Computer and information sciences
subject: Computer Software

description: This short position paper was presented at the International Workshop on Refactoring and Testing (RefTest) June 2013.
A Corpus Linguistics-based Approach for Estimating Arabic Online Content
Creators: name: Tawileh, Anas
name: Ghamdi, Mansour Al
Publisher: name: figshare
Year: 2015
Subjects: Computer Engineering

description: This paper presents the results of a research project for the development of a corpus-based indictor for Arabic online content. The project entailed the construction and analysis of three Arabic language corpora from online and offline sources. These corpora where then utilized in the estimation of the index size of two major search engines. The overlap between these two indices was determined, and an indication of the size of the indexed Arabic web was deduced. The developed indicator suggests that the current size of the indexed Arabic web exceeds 400 million pages.
title: Grade V renal vascular avulsion in blunt trauma
Creators: name: Ortega, Valeria
Publisher: name: EURORAD
Year: 2024
Subjects: subject: Interventional radiology
subject: Abdomen
subject: Arteries / Aorta
subject: Interventional vascular
subject: Kidney
subject: Catheter arteriography
subject: CT
subject: Trauma
subject: Clinical Cases

description: Clinical History: A 23-year-old male presented with chest pain to the emergency department after a motor vehicle accident. Vital signs showed tachycardia and hypotension. On examination, pale, diaphoretic, abdomen with mild tenderness in epigastrium, no guarding. Focused assessment with sonography with trauma (FAST) showed a small amount of fluid over the left lobe of the liver, and the right kidney appearance was not clear.

description: 23 years, male
The hydrogen storage capacity of coinage metalated benzenes studied by DFT
Creators: name: Tsipis, Athanassios C.
name: Gkarmpounis, Dimitrios N.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: The hydrogen storage capacity of representative cuprated benzenes (C6H5Cu and 1,3,5-Cu3C6H3 molecules) has been investigated by DFT calculations and found to fulfill the US department of energy target requirements for low-cost hydrogen storage materials. A thorough analysis of the bonding Cu(η2-H2) interactions by a multitude of electronic structure calculation methods (natural bond orbital, AIM, electron localization function, reduced density gradient, and Sign(λ2(r))ρ(r) functions) showed that these interactions exhibit a mixed covalent-ionic character accompanied by weak intermolecular dispersion interactions as well.
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.
Creators: name: Nelson, Jessica K
name: Thin, May Zaw
name: Evan, Theodore
name: Howell, Steven
name: Wu, Mary
name: Almeida, Bruna
name: Legrave, Nathalie
name: Koenis, Duco S
name: Koifman, Gabriela
name: Sugimoto, Yoichiro
name: Sopena, Miriam Llorian
name: MacRae, James
name: Nye, Emma
name: Howell, Michael
name: Snijders, Ambrosius P
name: Prachalias, Andreas
name: Zen, Yoh
name: Sarker, Debashis
name: Behrens, Axel
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Model organisms
subject: Biochemistry & Proteomics
subject: Tumour Biology
subject: Signalling & Oncogenes
subject: Gene Expression
subject: Genetics & Genomics
subject: Developmental Biology
subject: Genome Integrity & Repair
subject: Human Biology & Physiology
subject: Cell Biology
subject: Stem Cells
subject: Chemical Biology & High Throughput
subject: Infectious Disease
subject: Immunology
subject: FOS: Clinical medicine
subject: Metabolism
subject: Computational & Systems Biology

description: Deubiquitylating enzymes (DUBs) play an essential role in targeted protein degradation and represent an emerging therapeutic paradigm in cancer. However, their therapeutic potential in pancreatic ductal adenocarcinoma (PDAC) has not been explored. Here, we develop a DUB discovery pipeline, combining activity-based proteomics with a loss-of-function genetic screen in patient-derived PDAC organoids and murine genetic models. This approach identifies USP25 as a master regulator of PDAC growth and maintenance. Genetic and pharmacological USP25 inhibition results in potent growth impairment in PDAC organoids, while normal pancreatic organoids are insensitive, and causes dramatic regression of patient-derived xenografts. Mechanistically, USP25 deubiquitinates and stabilizes the HIF-1α transcription factor. PDAC is characterized by a severely hypoxic microenvironment, and USP25 depletion abrogates HIF-1α transcriptional activity and impairs glycolysis, inducing PDAC cell death in the tumor hypoxic core. Thus, the USP25/HIF-1α axis is an essential mechanism of metabolic reprogramming and survival in PDAC, which can be therapeutically exploited.
SUD HUJJATLARINING HUQUQNI QO'LLASH HUJJATLARI TIZIMIDAGI O'RNI.
Creators: name: Tog'oyeva, Malikabonu
Publisher: name: Zenodo
Year: 2024

description: Mazkur maqolada huquqni qo‘llash hujjatlari tushunchasi, ularning normativ-huquqiy hujjatlardan farqi, shu bilan birga, huquqni qo‘llash hujjatlari tizimida sud hujjatlarning tutgan o‘rni hamda ahamiyatiga doir ilmiy-nazariy qarashlar ilgari surilgan. Shuningdek, maqolada sud hujjatlarida qonun ustuvorligi va adolat tamoyillarining mustahkamlanishi yuzasidan bir qancha takliflar berib o‘tilgan.
MPEC 2025-E53 : DAILY ORBIT UPDATE (2025 March 3)
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2025
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Spade nella Sardegna nuragica: tipologia, contesti, problematiche
Creators: name: Matta, Marco
Publisher: name: Layers. Archeologia Territorio Contesti
Year: 2024

description: Riassunto: Il contributo propone riflessioni di natura tipologica, funzionale e socioculturale in relazione ai manufatti rientranti nelle categorie delle spade e delle daghe cronologicamente inquadrabili nel contesto della Sardegna nuragica (Bronzo Medio – Primo Ferro), con la sola esclusione dei manufatti denominati «spade votive».


 
description: Layers. Archeologia Territorio Contesti, N° 9 (2024)
Structure and petrography of the southwestern margin of the Biella pluton, Western Alps
Creators: name: Zanoni, Davide
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: This work presents a new form surface map of the southwestern margin of the Biella pluton at the scale 1:10,000. The Biella pluton is part of the Periadriatic intrusives of the Alps and is emplaced in the continental Sesia-Lanzo Zone of the western Austroalpine domain. The country rocks consist of metapelites and different metagranitoids. Pre-intrusive HP (high pressure) mineral assemblages are dominant in country rocks with the exception of metagranitoids dominated by HT (high temperature) assemblages. The plutonic rocks consist of monzonite with minor syenite. The ductile polyphasic deformation of the country rocks predates the pluton emplacement, with the exception of syn-intrusive folding and shearing, which were recorded in the country rocks of the deeper part of the pluton. Syn-intrusive deformation may be represented by brittle structures that bear mineralisation; however, the majority of the brittle deformation postdates the final emplacement of the pluton. The orientation of the pervasive foliation in the country rocks controls the space available for magma intrusion and possible magmatic flow during emplacement. The inferred diffusion of the thermal aureole in the country rocks is based on the variation in contact metamorphic minerals, which is described by microscopic analysis. The extent of the aureole appears to be controlled by the type of dominant mineral assemblages, rock permeability, and the orientation of the regional foliation in country rocks with respect to the pluton margin. The multiscale structural analysis reveals that the Biella pluton emplaced at a depth as shallow as the greenschist facies conditions or shallower.
Structure and petrography of the southwestern margin of the Biella pluton, Western Alps
Creators: name: Zanoni, Davide
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: This work presents a new form surface map of the southwestern margin of the Biella pluton at the scale 1:10,000. The Biella pluton is part of the Periadriatic intrusives of the Alps and is emplaced in the continental Sesia-Lanzo Zone of the western Austroalpine domain. The country rocks consist of metapelites and different metagranitoids. Pre-intrusive HP (high pressure) mineral assemblages are dominant in country rocks with the exception of metagranitoids dominated by HT (high temperature) assemblages. The plutonic rocks consist of monzonite with minor syenite. The ductile polyphasic deformation of the country rocks predates the pluton emplacement, with the exception of syn-intrusive folding and shearing, which were recorded in the country rocks of the deeper part of the pluton. Syn-intrusive deformation may be represented by brittle structures that bear mineralisation; however, the majority of the brittle deformation postdates the final emplacement of the pluton. The orientation of the pervasive foliation in the country rocks controls the space available for magma intrusion and possible magmatic flow during emplacement. The inferred diffusion of the thermal aureole in the country rocks is based on the variation in contact metamorphic minerals, which is described by microscopic analysis. The extent of the aureole appears to be controlled by the type of dominant mineral assemblages, rock permeability, and the orientation of the regional foliation in country rocks with respect to the pluton margin. The multiscale structural analysis reveals that the Biella pluton emplaced at a depth as shallow as the greenschist facies conditions or shallower.
Towards accurate modelling of galaxy clustering on small scales: testing the standard ?CDM + halo model
Creators: name: Sinha, Manodeep
name: Berlind, Andreas A.
name: McBride, Cameron K.
name: Scoccimarro, Roman
name: Piscionere, Jennifer
name: Wibking, Benjamin D.
Publisher: name: Swinburne
Year: 2024
Subjects: classificationCode: 5101
subject: Astronomical sciences

description: Interpreting the small-scale clustering of galaxies with halo models can elucidate the connection between galaxies and dark matter haloes. Unfortunately, the modelling is typically not sufficiently accurate for ruling out models statistically. It is thus difficult to use the information encoded in small scales to test cosmological models or probe subtle features of the galaxy-halo connection. In this paper, we attempt to push halo modelling into the 'accurate' regime with a fully numerical mock-based methodology and careful treatment of statistical and systematic errors. With our forward-modelling approach, we can incorporate clustering statistics beyond the traditional two-point statistics. We use this modelling methodology to test the standard A cold dark matter (ACDM) + halo model against the clustering of Sloan Digital Sky Survey (SDSS) seventh data release (DR7) galaxies. Specifically, we use the projected correlation function, group multiplicity function, and galaxy number density as constraints. We find that while the model fits each statistic separately, it struggles to fit them simultaneously. Adding group statistics leads to a more stringent test of the model and significantly tighter constraints on model parameters. We explore the impact of varying the adopted halo definition and cosmological model and find that changing the cosmology makes a significant difference. The most successful model we tried (Planck cosmology with Mvir haloes) matches the clustering of low-luminosity galaxies, but exhibits a 2.3 sigma tension with the clustering of luminous galaxies, thus providing evidence that the 'standard' halo model needs to be extended. This work opens the door to adding interesting freedom to the halo model and including additional clustering statistics as constraints.
Estrategias de marketing en los museos de España y Latinoamérica
Creators: name: Recuero-Virto, Nuria
Publisher: name: Zenodo
Year: 2024

description: This report is associated with the following publication:

Recuero-Virto, N. R., Blasco López, M. F. , & San-Martín, S. (2017). How can European museums reach sustainability? Tourism Review, 72(3), 303–318. https://doi.org/10.1108/tr-03-2017-0038

For more information, please visit: https://doi.org/10.1108/tr-03-2017-0038
A bilayer composite composed of TiO2-incorporated electrospun chitosan membrane and human extracellular matrix sheet as a wound dressing
Creators: name: Woo, Chang Hee
name: Choi, Young Chan
name: Choi, Ji Suk
name: Lee, Hee Young
name: Cho, Yong Woo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Physics
subject: Biochemistry

description: We designed bilayer composites composed of an upper layer of titanium dioxide (TiO2)-incorporated chitosan membrane and a sub-layer of human adipose-derived extracellular matrix (ECM) sheet as a wound dressing for full-thickness wound healing. The dense and fibrous top layer, which aims to protect the wound from bacterial infection, was prepared by electrospinning of chitosan solution followed by immersion in TiO2 solution. The sponge-like sub-layer, which aims to promote new tissue regeneration, was prepared with acellular ECM derived from human adipose tissue. Using a modified drop plate method, there was a 33.9 and 69.6% reduction in viable Escherichia coli and Staphylococcus aureus on the bilayer composite, respectively. In an in vivo experiment using rats, the bilayer composites exhibited good biocompatibility and provided proper physicochemical and compositional cues at the wound site. Changes in wound size and histological examination of full-thickness wounds showed that the bilayer composites induced faster regeneration of granulation tissue and epidermis with less scar formation, than control wounds. Overall results suggest that the TiO2-incorporated chitosan/ECM bilayer composite can be a suitable candidate as a wound dressing, with an excellent inhibition of bacterial penetration and wound healing acceleration effects.
The hydrogen storage capacity of coinage metalated benzenes studied by DFT
Creators: name: Tsipis, Athanassios C.
name: Gkarmpounis, Dimitrios N.
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Cell Biology
subject: Biochemistry
subject: Biophysics

description: The hydrogen storage capacity of representative cuprated benzenes (C6H5Cu and 1,3,5-Cu3C6H3 molecules) has been investigated by DFT calculations and found to fulfill the US DOE target requirements for low cost hydrogen storage materials. A thorough analysis of the bonding Cu∙∙∙(η2-H2) interactions by a multitude of electronic structure calculation methods (NBO, AIM, ELF, RDG and Sign(λ2(r))ρ(r) functions) showed that these interactions exhibit a mixed covalent-ionic character accompanied by weak intermolecular dispersion interactions as well.
title: Heimatbuch Dübendorf 1999
title: Dübendorfer Heimatbuch
titleType: AlternativeTitle
Creators: name: Bäumle, Hans
name: Berliat, Alberto
name: Bloch, Peter
name: Borer, Arnold
name: Dingee-Miller, Grace
name: Dürig, Walter
name: Guggisberg, Kathrin
name: Hauswirth, Fritz
name: Horvàth, Stefan
name: Korthals, Max
name: Kuhnt, Achim
name: Lanzendörfer, Christian
name: Meier, Albert
name: Schläpfer, Ernst
name: Schwyzer, Martin
name: Spahr-Temperli, Ruth
name: Starke, Monika
name: Trachsler-Geiger, Trudi
name: Trachsler, Hans-Felix
name: Weder, Christoph
name: Wichers, Gunnar
Publisher: name: Verkehrs- und Verschönerungsverein
Year: 1999
Subjects: subject: 914 Geografie Europas und Reisen in Europa
subject: 949 Geschichte anderer Teile Europas
subject: Dübendorf
subject: Heimatkunde

description: Enthält eine Chronik der Gemeinde Dübendorf vom 1. Oktober 1998 bis 30. September 1999
A bilayer composite composed of TiO2-incorporated electrospun chitosan membrane and human extracellular matrix sheet as a wound dressing
Creators: name: Woo, Chang Hee
name: Choi, Young Chan
name: Choi, Ji Suk
name: Lee, Hee Young
name: Cho, Yong Woo
Publisher: name: Taylor & Francis
Year: 2015
Subjects: subject: Biological Sciences
subject: Chemistry
subject: Earth and Environmental Sciences
subject: Biotechnology
subject: Pharmacology
subject: Physiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Cell Biology
subject: Physics
subject: Biochemistry

description: We designed bilayer composites composed of an upper layer of titanium dioxide (TiO2)-incorporated chitosan membrane and a sub-layer of human adipose-derived extracellular matrix (ECM) sheet as a wound dressing for full-thickness wound healing. The dense and fibrous top layer, which aims to protect the wound from bacterial infection, was prepared by electrospinning of chitosan solution followed by immersion in TiO2 solution. The sponge-like sub-layer, which aims to promote new tissue regeneration, was prepared with acellular ECM derived from human adipose tissue. Using a modified drop plate method, there was a 33.9% and 69.6% reduction in viable E. coli and S. aureus on the bilayer composite, respectively. In an in vivo experiment using rats, the bilayer composites exhibited good biocompatibility and provided proper physicochemical and compositional cues at the wound site. Changes in wound size and histological examination of full-thickness wounds showed that the bilayer composites induced faster regeneration of granulation tissue and epidermis with less scar formation, than control wounds. Overall results suggest that the TiO2-incorporated chitosan/ECM bilayer composite can be a suitable candidate as a wound dressing, with excellent inhibition of bacterial penetration and wound healing acceleration effects.
ИОСИП БРОЗ ТИТО. ДОРОГА К ВЛАСТИ
Creators: name: Митин С. В.
name: Тараскина А. Д.
Publisher: name: Контентус
Year: 2020
Subjects: Иосип Броз Тито
политика
КПЮ
Югославия
революция
восстание
КСХС

description: В статье рассмотрена биография известного югославского революционера, политического, государственного и военного деятеля Иосипа Броз Тито, изучены периоды становления и развития его политических взглядов.
title: Обеспечение прав несовершеннолетних детей на получение содержания от своих родителей: новое в правовом регулировании
Creators: name: Дорошенко, Татьяна
name: Макарова, Елена
Publisher: name: Новгородский государственный университет имени Ярослава Мудрого (НовГУ)
Year: 2022

description: Статья посвящена актуальным вопросам трансформации нормативного и правоприменительного регулирования алиментных правоотношений. На основе анализа статистических данных делается вывод
о недостаточной эффективности действующих в последние годы мер обеспечения прав ребенка на содержания от своих родителей (алиментные выплаты), в том числе и через исполнительное производство. Авторы
рассматривают принятые в 2021 году на федеральном уровне изменения в законодательные и подзаконные акты, регламентирующие новые правила по взысканию алиментов, которые смогут изменить ситуацию в исследуемой области. Ряд нововведений изучается в сравнении с зарубежным опытом регулирования обеспечения прав детей на получение содержания от своих родителей. В первую очередь, это касается продолжения алиментных выплат при смерти алиментоплательщика, а также введения нового института
государственной поддержки детей должников Алиментного фонда.
Impact of mental resilience and perceived immune functioning on the severity of alcohol hangover
Creators: name: Van De Loo, Aurora J. A. E.
name: Van Schrojenstein Lantman, Marith
name: Mackus, Marlou
name: Scholey, Andrew
name: Verster, Joris
Publisher: name: Swinburne
Year: 2024

description: Objective: Recent research comparing hangover sensitive drinkers with hangover resistant drinkers has revealed that experiencing alcohol hangovers is associated with significantly poorer self-reported immune functioning (p < 0.0001). No significant difference between the groups was found on mental resilience. The objective of the current survey was to examine the association between hangover severity, perceived immune status, and mental resilience. N = 341 Dutch students, all hangover sensitive drinkers, completed an online survey. The Brief Resilience Scale was completed, and perceived immune functioning and overall hangover severity for their latest past month hangover were assessed. Results: Students consumed a mean (SD) of 12.3 (5.9) alcoholic drinks the evening before their latest hangover. A significant positive association was found between mental resilience and perceived immune functioning (r = 0.372, p = 0.000). No significant associations of hangover severity were found with mental resilience (r = - 0.010, p = 0.858), or perceived immune functioning (r = - 0.025, p = 0.645). Previous research revealed that hangover resistant and hangover sensitive drinkers report having significantly different levels of immune functioning, and that the immune system is involved in the development of alcohol hangover. These findings suggest that levels of mental resilience and perceived immune functioning are not related to the severity of hangovers in hangover sensitive drinkers.
Transition-metal-doped Fe2O3 nanoparticles for oxygen evolution reaction
Creators: name: Yin, Yichun
name: Zhang, Xiwang
name: Sun, Chenghua
Publisher: name: Swinburne
Year: 2024

description: Hematite (α-Fe2O3) has been extensively studied as a promising photocatalyst, with the capacity to split water under visible light. To tune its electronic structure and improve the performance for oxygen evolution reaction (OER), high-quality single crystals of α-Fe2O3 nanoparticles were synthesized and doped by various transition metals (M=V, Cr, Mn, Zn, Co, Ni, Cu, Nb, Mo, Ti) by a molten-salt flux method. Optical, electronic and catalytic properties of transition-metal-doped α-Fe2O3 (TM-doped α-Fe2O3) have been systematically investigated. Cobalt has been identified as the best dopant for α-Fe2O3, reducing the OER overpotential by 0.16 V with respect to the undoped.