cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: ÐÐµÑÑÐ¿ÐµÐºÑÐ¸Ð²Ñ ÑÐ°Ð·Ð²Ð¸ÑÐ¸Ñ Ð²Ð·Ð°Ð¸Ð¼Ð¾ÑÐ²ÑÐ·ÐµÐ¹ Ð Ð¾ÑÑÐ¸Ð¸ ÑÐ¾ ÑÑÑÐ°Ð½Ð°Ð¼Ð¸ Ð¡ÐÐ
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: Ð¥Ð°Ð¼Ð¸Ð´ÑÐ»Ð»Ð¸Ð½Ð°, ÐÐ¸Ð³Ð¸Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ñ
Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð¿ÑÐ¾ÑÐµÑÑÑ
Ð²Ð½ÐµÑÐ½ÑÑ Ð¿Ð¾Ð»Ð¸ÑÐ¸ÐºÐ°
Ð²Ð·Ð°Ð¸Ð¼Ð¾Ð¾ÑÐ½Ð¾ÑÐµÐ½Ð¸Ñ ÑÐ¾ ÑÑÑÐ°Ð½Ð°Ð¼Ð¸ Ð¡ÐÐ

description: ÐÐ±ÑÐµÐºÑÐ¾Ð¼ Ð¸ÑÑÐ»ÐµÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ ÑÐ²Ð»ÑÑÑÑÑ Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð¿ÑÐ¾ÑÐµÑÑÑ Ð Ð¾ÑÑÐ¸Ñ-Ð¡ÐÐ.
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Additional file 4 of TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats
Creators: name: Liang, Hui
name: Matei, Nathanael
name: McBride, Devin W.
name: Xu, Yang
name: Zhou, Zhenhua
name: Tang, Jiping
name: Luo, Benyan
name: Zhang, John H.
Publisher: name: figshare
Year: 2021
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Mental Health

description: Additional file 4: Table S1. Animal number (Survival/total) in each group. Table S2. Physiological parameters
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° back-end ÑÐ°ÑÑÐ¸ Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ð³Ð¾ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ-Ð°Ð³ÑÐµÐ³Ð°ÑÐ¾ÑÐ°
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ²ÑÐ¸Ð½Ð½Ð¸ÐºÐ¾Ð², ÐÑÑÐµÐ¼
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: IT-ÑÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ð¸
Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½Ð¾Ðµ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ðµ
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description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð¸Ð·Ð»Ð¾Ð¶ÐµÐ½Ð° ÑÑÑÐ½Ð¾ÑÑÑ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð° Ðº ÑÐ¾Ð·Ð´Ð°Ð½Ð¸Ñ ÑÐµÑÐ²Ð¸ÑÐ¾Ð²-Ð°Ð³ÑÐµÐ³Ð°ÑÐ¾ÑÐ¾Ð² Ð² ÑÑÐµÑÐµ ÑÐ¾ÑÐ³Ð¾Ð²Ð»Ð¸ Ð½Ð° Ð¾ÑÐ½Ð¾Ð²Ðµ Ð¿Ð¾Ð´ÑÐ¾Ð´Ð° REST API Ñ Ð¸ÑÐ¿Ð¾Ð»ÑÐ·Ð¾Ð²Ð°Ð½Ð¸ÐµÐ¼ Swift 4.0 - Ð½Ð°ÑÐ¸Ð²Ð½Ð¾Ð³Ð¾ ÑÐ·ÑÐºÐ° Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð´ Ð¿Ð»Ð°ÑÑÐ¾ÑÐ¼Ñ iOS. ÐÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ñ ÑÐµÑÐµÐ½Ð¸Ð¹ Ð² Ð²ÑÐ±ÑÐ°Ð½Ð½Ð¾Ð¼ ÑÐµÐ³Ð¼ÐµÐ½ÑÐµ. ÐÐ·ÑÑÐµÐ½Ñ Ð¿Ð¾Ð´ÑÐ¾Ð´Ñ Ðº ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð²ÐµÐ±-ÑÐµÑÐ²Ð¸ÑÐ¾Ð². Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° ÐºÐ¾Ð½ÐºÑÐµÑÐ½Ð°Ñ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð°Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ñ Ð²Ð·Ð°Ð¸Ð¼Ð¾Ð´ÐµÐ¹ÑÑÐ²Ð¸Ñ ÐºÐ»Ð¸ÐµÐ½ÑÑÐºÐ¾Ð¹ ÑÐ°ÑÑÐ¸ Ð¿ÑÐ¸Ð»Ð¾Ð¶ÐµÐ½Ð¸Ñ Ñ ÑÐµÑÐ²ÐµÑÐ°Ð¼Ð¸.
eta/s is critical (at phase transitions)
Creators: name: Dobado, Antonio
name: Llanes-Estrada, Felipe J.
name: Torres-Rincon, Juan M.
Publisher: name: arXiv
Year: 2008
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The viscosity over entropy density ratio, or KSS number, can help isolate the critical point in the hadron phase-diagram in Relativistic Heavy Ion Collisions. We argue that this quantity does have a minimum at a phase transition or crossover. Although indications from conventional non-relativistic gases point out to even a divergence in eta/s when the phase-transition is first-order, since the critical exponent is rather low, this will be more difficult to ascertain in RHIC or FAIR. The experimental data are more likely to reveal a discontinuity for a first order phase transition or a smooth minimum at a crossover.
description: 3-pages, 2 figures, contribution to XIII Mexican School of Particles and Fields, to be published in AIP-proceedings
Acquisition of structural loads applied to a backcountry ski boot for the validation of bench tests
Creators: name: Crosetta, Lorenzo
name: Petrone, Nicola
name: Prenol, Leonardo
name: Colombo, Daniel
name: Zullo, Giuseppe
name: Colonna, Martino
Publisher: name: Loughborough University
Year: 2024

description: Engineering of Sport 15 - Proceedings from the 15th International Conference on the Engineering of Sport (ISEA 2024)
In the design of ski boot prototypes, two fundamental tests sessions are employed for assessing stiffness & strength. First, in laboratory ski boot bench testing the conventional Flex Index and fatigue life are determined; then, field tests give confirmation of boot performance and safety levels. Frequently, failures observed in the laboratory setting do not necessarily manifest during on-field trials, and vice versa. This adds complexity to the prototypes assessment process, leading to an undetermined overdesign of the ski boots as a precautionary measure. Consequently, a targeted study is needed to collect the field force system acting on ski boot components and to tune accordingly laboratory bench tests.
Physarum notabile T. Macbr.
Creators: name: Kluša, Julita
Publisher: name: Zenodo
Year: 2023
Subjects: Biodiversity
Taxonomy
Protozoa
Mycetozoa
Myxomycetes
Physarales
Physaraceae
Physarum
Physarum notabile

description: ● Physarum cf. notabile T. Macbr.,
daudzveidīgā pumpurīte
- leg. V.Sīmansone, 04 Oct 2020, Sēja p., on a log of Populus tremula in aspen-spruce forest; leg. E.Oļehnoviča, 11 Oct 2020, Vaive p., on mosses in a forest by the river, det. J. Kluša, 2023; (NMKK), quite rare; 12 samples from different localities in Latvia (2020-2022, mostly October), often several sporocarps grow closely together, with fused stalks; stalks white, spores dark with white line; sporocarps look like Ph. leucopus, spores look like Ph. notabile (Fig. 4). E.Johannesen (pers. comm.): "Should be barcoded".
description: Published as part of Kluša, Julita, 2023, Complete Checklist Of Myxomycetes In Latvia, pp. 127-151 in Acta Biologica Universitatis Daugavpiliensis 23 (2) on pages 127-151, DOI: 10.59893/abud.23(2).002, http://zenodo.org/record/12650118
Electrical control of Kondo effect and superconducting transport in a side-gated InAs quantum dot Josephson junction
Creators: name: Kanai, Y.
name: Deacon, R. S.
name: Oiwa, A.
name: Yoshida, K.
name: Shibata, K.
name: Hirakawa, K.
name: Tarucha, S.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: We measure the non-dissipative supercurrent in a single InAs self-assembled quantum dot (QD) coupled to superconducting leads. The QD occupation is both tuned by a back-gate electrode and lateral side-gate. The geometry of the side-gate allows tuning of the QD-lead tunnel coupling in a region of constant electron number with appropriate orbital state. Using the side-gate effect we study the competition between Kondo correlations and superconducting pairing on the QD, observing a decrease in the supercurrent when the Kondo temperature is reduced below the superconducting energy gap in qualitative agreement with theoretical predictions.
FACILITATE DELIBERATION. TOWARDS A PROFESSIONALIZATION OF THE BIOETHICAL EXPERT IN THE PUBLIC ARENA.
Creators: name: SANCHINI, VIRGINIA
Publisher: name: Universit� degli Studi di Milano
Year: 2016

description: In an increasingly specialized world, where the production of knowledge and its acquisition have become a collective enterprise, nobody can master all the fields alone. This has led to the proliferation of a myriad of experts, each of whom is specialized in a precise domain or subdomain. Given this picture, it is not surprising that people with training in bioethics are often referred to as ?bioethics experts? and/or ?bioethical experts?. However, far from being confined to a specific social dimension, in today?s society bioethicists are a commonplace presence in an ever-increasing range of domains. In recognition of this phenomenon, the aim of this thesis is to explore the so-called issue of bioethical expertise. This means first and foremost exploring two main questions: whether an expertise in the field of bioethics might actually exist and what are, if any, the skills that the bioethical expert is endowed with, in order to understand whether this figure is on a par with professionals of other disciplines. After presenting a general review of the current literature on this issue and briefly indicating the different research paths this research topic might lead to, the focus will be narrowed to dwell on the main research questions this work aims to address: is there a legitimate role for the bioethical expert within the public arena, and, if so, what is this role? Far from being a straightforward question, this issue is further complicated by a vast literature decrying the threat posed by bioethicists with respect to the broader context in which they operate: liberal democracies. In taking these considerations seriously, this dissertation aims to ?solve the paradox? connected with the figure of bioethical expert and to propose a normative model of bioethical expert which aims to be compatible with the tenets of liberal democracies and, in particular, their public decision-making processes. This figure will be defined here as the facilitator of deliberation, thus recognizing the debt it has towards the political theories of deliberative democracy. This work is structured as follows: first of all the theoretical current debate concerning the topic of bioethical expertise is presented. Secondly, by narrowing the focus of investigation I concentrate on the domain in which the bioethical expert proposed here has to operate: public bioethics. The normative proposal of bioethical expert as facilitator of deliberation is then presented, remodelling the former in relation to the already existing figures occupying the public arena. Finally, the results of a preliminary experiment, designed to empirically explore this new figure, are presented and discussed. ?
A Poincaré invariant treatment of the three-nucleon problem
Creators: name: Polyzou, W.
name: Tucker, M.
name: Veerasamy, S.
name: Elster, Ch.
name: Lin, T.
name: Glöckle, W.
name: Witała, H.
name: Golak, J.
name: Skibiński, R.
name: Kamada, H.
name: Keister, B.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: I summarize recent progress in the treatment of the Poincaré three-nucleon problem at intermediate energies
description: Contribution to Light Cone 2008, Mulhouse France, 7 pages, 2 figures
DECODING MOLECULAR AND PHENOTYPIC PROPERTIES OF PROLIFERATING CELLS UNDER CONSTANT MITOTIC CHECKPOINT ACTIVATION
Creators: name: CORNO, ANDREA
Publisher: name: Universit� degli Studi di Milano
Year: 2018

description: During mitosis, DNA material needs to be properly segregated. Chromosome segregation is triggered by the Anaphase Promoting Complex or Cyclosome (APC/C), an E3 ubiquitin ligase activated by its cofactor Cdc20. Activation of APC:Cdc20 is conditioned by the presence of optimal conditions for a proper partition of sister chromatids. Without such conditions, activation of APC/C:Cdc20 could lead to unequal chromosome segregation, by which an aneuploid progeny could arise. The Spindle Assembly Checkpoint (SAC) inhibits the activity of APC/C:Cdc20, blocking the progression through the cell cycle and thus preventing erroneous chromosome segregation. When cells experience a prolonged SAC activation, they may die in mitosis by apoptosis, or overcome the arrest and progress into the cell cycle even when chromosome segregation is impaired. The second scenario is also known as adaptation to the SAC (or mitotic slippage). Once adapted, cell proliferation can still be blocked (via apoptosis or G1 arrest) or cells can resume cell division. The latter case may establish a progeny of cells in which aneuploidy and genomic instability introduce large genetic variability, with potentially irreversible and deleterious effect on the cell population. Using S. cerevisiae as a model organism, we characterized a population of cells escaped from a prolonged mitotic arrest, which we called adapted cells. Proteomic analysis of these cells revealed large rewirings of biological processes and pathways, suggesting a pseudo "differentiated" state for adapted cells. The cell cycle of adapted cell is heavily modified, to account for the chronic inhibition of APC/C:Cdc20. On the one hand, APC/C:Cdc20 itself become less responsive to the SAC, as observed in a population of cells where we uncoupled adaptation from missegregation. We showed that cellular size was not responsible for the partial recovery of APC/C:Cdc20 activity in the presence of the SAC. Our data rather suggest a role for Cdc28-mediated phosphorylation. On the other hand, other activators of APC/C like Cdh1 become essential, unlike what observed in a regular cell cycle. The synthetic lethality of adapted cells with mitotic exit genes suggests potential molecular targets for specific inhibition of adapted cells.
Simultaneously improving mechanical and magnetic properties through heterogeneous lamella structures in a superalloy-like, soft magnetic complex concentrated alloy
Creators: name: Liu, Xiao
name: Vecchio, Kenneth
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer

description: Heterogeneous lamella (HL) structures were produced via simple processing steps in a FeCoNi-based complex concentrated alloy (CCA) with superalloy-like FCC/L12 microstructure. Compared to the homogeneous-structured control specimens, the HL-structured specimens exhibited synergic enhancements in strengths and ductility (with σy up to 1 GPa, σu up to 1.4 GPa, and ϵt up to 16.5%), and at the same time, higher saturation magnetization and lower coercivity (with Ms up to 104 Am2 kg−1 and Hc as low as 833 A/m). The results obtained in this study provide insights to enhancing mechanical properties in structural soft magnetic materials without sacrificing their magnetic properties. The current work presents a simple and effective strategy that can be applied to soft magnetic alloys with superalloy-like microstructures for simultaneous enhancements of mechanical and magnetic properties.
BIOLOGICAL SIGNIFICANCE OF ALTERATIONS IN BRCA1 AND BRCA2 GENES AND RESPONSE TO DNA DAMAGE AGENTS IN HEREDITARY BREAST CANCER
Creators: name: PALADINI, LAURA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Background: Although the large number of studies investigating BRCA mutations and their clinical role in different populations and ethnicities, there is a lack of a systematic analysis on these alterations in Italian cohorts, including the analysis of Variants of Unknown biological and clinical Significance (VUS). Moreover, correct management of breast cancer patients tested positive for alterations in BRCA1 or BRCA2 genes is still controversial. We aimed to assess the biological and clinical relevance of BRCA alterations in a consecutive cohort of hereditary breast cancer patients, with particular attention to VUS. Methods: Genetic and clinical data from 366 patients with familial history of breast cancer were reviewed. The association between clinical-pathological, molecular data, and breast cancer patient subgroups was assessed. BRCA1/2 and ?-H2AX expression levels were assessed by qRT-PCR and IHC for all tumors. In silico protein prediction models were computed for VUS with potential clinical significance. Cell proliferation and apoptosis assays for CRISPR/Ca9s-generated mutant MDA-MB-231 cell line were performed to evaluate the sensitivity of specific VUS to DNA damage agents. Results: Overall, 73 breast cancer patients (20%) tested positive for BRCA1/2 alterations. BRCA1 and BRCA2 mutations were reported in 34 (46.5%) and 15 (20.5%) patients, respectively. Two patients (3%) showed two concurrent mutations in both genes. Twenty-two patients (30%) tested positive for VUS. Breast cancer family history and early onset of disease were significantly associated with BRCA1 (p < 0.001) and BRCA2 (p = 0.045 and p = 0.005) mutations. Triple-negative histotype, grading 3, and high Ki-67 levels were significantly associated with BRCA1 mutations (p < 0.001). Molecular, in silico and in vitro experiments confirmed the deleterious effect of BRCA1 c.5509T>C VUS, which was associated with significant high levels of DNA damage and greater sensitivity to Olaparib compared to Cisplatin treatment. Conclusions: Our study supports the deleterious effect of the BRCA1 c.5509T>C VUS in hereditary breast cancer patients, and suggests that breast cancer patient carriers of this variant could benefit from an intense surveillance and from a single agent treatment with Olaparib avoiding various side effects of chemotherapy treatment.
CULTURAL COMPETENCY-BASED INTERVENTIONS FOR HEALTH PROFESSIONALS IN EUROPE: A SCOPING REVIEW
Creators: name: Topa, Gabriela
name: González, M. Ángeles López
name: De-Maria, Berta
Publisher: name: Open Science Framework
Year: 2023
Subjects: subject: Psychology
subject: FOS: Psychology
subject: Medicine and Health Sciences
subject: Social and Behavioral Sciences
subject: Multicultural Psychology
subject: Social Psychology
subject: Health Psychology

description: Cultural competence in European healthcare;
The Relationship Between Intergalactic HI/OVI and Nearby (z<0.017) Galaxies
Creators: name: Wakker, B. P.
name: Savage, B. D.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We analyze intergalactic HI and OVI absorbers with v<5000 km/s in HST and FUSE spectra of 76 AGNs. The baryons traced by HI/OVI absorption are clearly associated with the extended surroundings of galaxies; for impact parameters <400 kpc they are ~5 times more numerous as those inside the galaxies. This large reservoir of matter likely plays a major role in galaxy evolution. We tabulate the fraction of absorbers having a galaxy of a given luminosity within a given impact parameter (rho) and velocity difference (Dv), as well as the fraction of galaxies with an absorber closer than a given rho and Dv. We identify possible "void absorbers" (rho>3 Mpc to the nearest L* galaxy), although at v<2500 km/s all absorbers are within 1.5 Mpc of an L>0.1 L* galaxy. The absorber properties depend on rho, but the relations are not simple correlations. For four absorbers with rho=50-350 kpc from an edge-on galaxy with known orientation of its rotation, we find no clear relation between absorber velocities and the rotation curve of the underlying galaxy. For rho<350 kpc the covering factor of Ly-alpha (OVI) around L>0.1 L* galaxies is 100% for field galaxies and 65% for group galaxies; 50% of galaxy groups have associated Ly-alpha. All OVI absorbers occur within 550 kpc of an L>0.25 L* galaxy. The properties of three of 14 OVI absorbers are consistent with photoionization, for five the evidence points to collisional ionization; the others are ambiguous. The fraction of broad Ly-alpha lines increases from z=3 to z=0 and with decreasing impact parameter, consistent with the idea that gas inside ~500 kpc from galaxies is heating up, although alternative explanations can not be clearly excluded.
description: ApJ Supplement, in press
Fine and hyperfine structure of the muonic ^3He ion
Creators: name: Elekina, E. N.
name: Martynenko, A. P.
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: On the basis of quasipotential approach to the bound state problem in QED we calculate the vacuum polarization, relativistic, recoil, structure corrections of orders $α^5$ and $α^6$ to the fine structure interval $ΔE^{fs}=E(2P_{3/2})-E(2P_{1/2})$ and to the hyperfine structure of the energy levels $2P_{1/2}$ and $2P_{3/2}$ in muonic $^3_2He$ ion. The resulting values $ΔE^{fs}= 144803.15 μeV$, $Δ\tilde E^{hfs}(2P_{1/2})=-58712.90 μeV$, $Δ\tilde E^{hfs}(2P_{3/2})=-24290.69 μeV$ provide reliable guidelines in performing a comparison with the relevant experimental data.
description: 15 pages, 4 figures, 3 tables
title: Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° Ð¿ÑÐµÐ´Ð»Ð¾Ð¶ÐµÐ½Ð¸Ð¹ Ð¿Ð¾ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð¼ÐµÑ Ð½ÐµÑÐ°ÑÐ¸ÑÐ½Ð¾Ð³Ð¾ (ÑÐµÑ Ð½Ð¸ÑÐµÑÐºÐ¾Ð³Ð¾) ÑÐµÐ³ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð² ÑÐ°Ð¼ÐºÐ°Ñ ÑÐ°Ð¼Ð¾Ð¶ÐµÐ½Ð½Ð¾Ð³Ð¾ ÑÐ¾ÑÐ·Ð° ÐÐÐ­Ð¡
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°ÑÐ¸Ð´Ð·Ð°Ð´Ðµ, Ð ÑÑÐ°Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ°Ñ Ð¸Ð½ÑÐµÐ³ÑÐ°ÑÐ¸Ñ
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DYSREGULATION OF THE GPR17 RECEPTOR IN NEURO-INFLAMMATORY DISEASES: IMPLICATIONS FOR RE-MYELINATION IN MULTIPLE SCLEROSIS
Creators: name: COPPOLINO, GIUSY TINDARA
Publisher: name: Universit� degli Studi di Milano
Year: 2017

description: Multiple Sclerosis (MS) is a chronic immune-mediated disease in which the immune system directs an abnormal response against myelin, an insulating lipidic structure produced by oligodendrocytes responsible of fast axonal electric transmission. During MS, demyelination disrupts neuronal conductance, leading to motor symptoms, and impairs oligodendroglial functions. Under these conditions, oligodendrocyte precursor cells (OPCs) are recruited at the injury site to re-myelinate damaged axons, but this process is often defective. Many disease-modifying treatments (DMTs) are available but there are several unmet needs: delaying disease progression, providing neuroprotection and promoting re-myelination. The aim of this thesis was to characterize GPR17 alterations both in murine MS models and in human MS lesions, to assess whether this receptor, a key actor of oligodendrogenesis, can be proposed as a pharmacological target in re-myelinating strategies. GPR17 is a G protein-coupled receptor activated by both uracil nucleotides and cysteinyl-leukotrienes, mediators involved in inflammatory responses in the CNS. Under physiological conditions, GPR17 is expressed in OPCs, with maximal levels in immature oligodendrocytes and progressive downregulated in terminally differentiating cells. A marked GPR17 up-regulation was found in rodent models of cerebral trauma, ischemia and in lysolecithin-induced focal demyelination; suggesting that GPR17 takes part in the pathological mechanisms of demyelination either as a consequence of the disease or contributing to the lesion. In mice with Experimental Autoimmune Encephalomyelitis (EAE), we observed a marked and persistent upregulation of GPR17 in the OPCs accumulating at demyelinating lesions. Conversely, no GPR17 upregulation was found in a model characterized by a much lower degree of inflammation, i.e. cuprizone-induced demyelination. In a similar way to EAE, in autoptic samples from MS patients, many GPR17-positive activated cells accumulated at the border of active lesions. Furthermore, we demonstrated that the chemokine CXCL12 can also directly act as a promiscuous activator of GPR17, corroborating our hypothesis of a common pathophysiological role for GPR17 and chemokine receptors in leading the re-myelination processes. Characterizing the molecular defects of GPR17 in MS will help re-establishing its correct function in re-myelination and foster the identification of new pharmacological strategies to enhance OPCs reparative potential in MS.
MPEC 2024-S81 : 2024 SU1
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2024
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469
subject: 2024 SU1

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
title: ÐÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ñ Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ¾ÑÐ³Ð¾Ð²Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿Ð¸Ð²Ð½Ð¾Ð³Ð¾ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð½Ð° 75 Ð¼ÐµÑÑ Ð² Ð³. Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³Ðµ
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ±ÑÐ°Ð·ÑÐ¾Ð², ÐÐ»ÐµÐ³
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2017
Subjects: Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð¾-ÑÐ¾ÑÐ³Ð¾Ð²Ð°Ñ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ
Ð¿ÑÐ¾Ð¸Ð·Ð²Ð¾Ð´ÑÑÐ²ÐµÐ½Ð½Ð°Ñ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð°
Ð¿Ð¸Ð²Ð½Ð¾Ð¹ ÑÐµÑÑÐ¾ÑÐ°Ð½

description: ÐÑÐ¿Ð¾Ð»Ð½ÐµÐ½Ð¾ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²Ð¾Ðµ Ð¾Ð±Ð¾ÑÐ½Ð¾Ð²Ð°Ð½Ð¸Ðµ Ð½ÐµÐ¾Ð±ÑÐ¾Ð´Ð¸Ð¼Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¸Ð²Ð½Ð¾Ð³Ð¾ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð°, Ð¿ÑÐ¾Ð¸Ð·Ð²ÐµÐ´ÐµÐ½Ñ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸ÑÐµÑÐºÐ¸Ðµ ÑÐ°ÑÑÐµÑÑ Ð¾Ð±Ð¾ÑÑÐ´Ð¾Ð²Ð°Ð½Ð¸Ñ, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ð° Ð¾ÑÐ³Ð°Ð½Ð¸Ð·Ð°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÑÑÐºÑÑÑÐ° Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ. Ð Ð°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ñ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ Ð¿Ð¾ Ð¾Ð±ÐµÑÐ¿ÐµÑÐµÐ½Ð¸Ñ Ð±ÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÐ¸ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐ¾ÐµÐºÑÐ¸ÑÑÐµÐ¼Ð¾Ð³Ð¾ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ñ, ÐµÐ³Ð¾ Ð¿Ð»Ð°Ð½Ð¸ÑÐ¾Ð²Ð¾ÑÐ½Ð¾Ðµ ÑÐµÑÐµÐ½Ð¸Ðµ Ð¸ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÐµ ÑÐºÐ¾Ð½Ð¾Ð¼Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¿Ð¾ÐºÐ°Ð·Ð°ÑÐµÐ»Ð¸.
Distribution and diversity of myxomycetes along the eleva-tional belt of Mt. Calavite Wildlife Sanctuary (MCWS),  Occidental Mindoro, Philippines
Creators: name: Racoma, Christon Jairus
Publisher: name: Zenodo
Year: 2024

description: R-script code for diversity and distribution of myxomycetes along elevational belt of MCWS, Occidental Mindoro.
Hadron Correlation in Jets on the Near and Away Sides of High-p_T Triggers in Heavy-ion Collisions
Creators: name: Hwa, Rudolph C.
name: Yang, C. B.
Publisher: name: arXiv
Year: 2008
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: Correlation between trigger and associated particles in jets produced on near and away sides of high-p_T triggers in heavy-ion collisions is studied. Hadronization of jets on both sides is treated by thermal-shower and shower-shower recombination. Energy loss of semihard and hard partons traversing the nuclear medium is parametrized in a way that renders good fit of the single-particle inclusive distributions at all centralities. The associated hadron distribution in the near-side jet can be determined showing weak dependence on system size because of trigger bias. The inverse slope increases with trigger momentum in agreement with data. The distribution of associated particle in the away-side jet is also studied with careful attention given to antitrigger bias that is due to the longer path length that the away-side jet recoiling against the trigger jet must propagate in the medium to reach the opposite side. Centrality dependence is taken into account after determining a realistic probability distribution of the dynamical path length of the parton trajectory within each class of centrality. For symmetric dijets with p_T^{trig}=p_T^{assoc}(away) it is shown that the per-trigger yield is dominated by tangential jets. The average parton momentum for the recoil jet is shown to be always larger than that of the trigger jet for fixed p_T^{trig} and centrality and for any measurable p_T^{assoc}(away). With the comprehensive treatment of dijet production described here it is possible to answer many questions regarding the behavior of partons in the medium under conditions that can be specified on measurable hadron momenta.
description: 17 pages in RevTex including 32 figures
High quality GeV proton beams from a density-modulated foil target
Creators: name: Yu, T. P.
name: Chen, M.
name: Pukhov, A.
Publisher: name: arXiv
Year: 2009
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Accelerator Physics (physics.acc-ph)
subject: FOS: Physical sciences

description: We study proton acceleration from a foil target with a transversely varying density using multi-dimensional Particle-in-Cell (PIC) simulations. In order to reduce electron heating and deformation of the target, circularly polarized Gaussian laser pulses at intensities of the order of 1022Wcm-2 are used. It is shown that when the target density distribution fits that of the laser intensity profile, protons accelerated from the center part of the target have quasi-monoenergetic spectra and are well collimated. In our two-dimensional PIC simulations, the final peak energy can be up to 1.4 GeV with the full-width of half maximum divergence cone of less than 4o. We observe highly efficient energy conversion from the laser to the protons in the simulations.
description: 10 pages, 6 figures, submitted to Laser and Particle Beams
The PivotBuoy Project: a Case Study of a Single Point Mooring system with a TLP
Creators: name: Casanovas, Carlos
Publisher: name: Zenodo
Year: 2023
Subjects: floating offshore wind

description: The Single Point Mooring (SPM) technology has been widely used in Oil & Gas for decades, specifically for the connection of FPSOs (Floating Production, Storage and Offloading), but remains unknown to most of the wind industry. Nonetheless, in recent years an increasing number of floating solutions have proposed the use of SPM systems instead of multiple mooring systems to explore the advantages of this new setup. For the past two years, X1 Wind has worked together with eight other partners from five different countries on the PivotBuoy project, a research and innovation action awarded under the Horizon 2020 program, with the objective to demonstrate a single point mooring system (SPM) which opens up new opportunities for floating offshore wind. The PivotBuoy system combines the advantages of a SPM with a small Tension-Leg Platform (TLP), which coupled with a downwind turbine configuration, enables a complete redesign of the floating structure, and simplifies the installation process. The PivotBuoy system allows the floating structure to passively weathervane and self-align with the wind, without the need of an active yaw system.
 In October, the project successfully installed the fully functional prototype (X30) of the PivotBuoy system, integrated with a downwind-adapted Vestas V29, at PLOCAN’s test site in the Canary Islands. This represents a major milestone for the industry as the TLP was installed using only local vessels, thus greatly simplifying the installation procedures typically required for this type of mooring system. The platform will be tested under real conditions until March 2023, and by the time of the conference, X1 Wind will be able to share results about the platform’s stability and performance, as well as its installation procedures. These results will contribute to the technical knowledge of TLP designs and could open the door for additional academic work regarding this type of mooring.
The 4 P’s of enactment: purpose, praxis, problems, and policy lessons from a framework on ethos
Creators: name: Mulpeter, Niall
name: Mc Cormack, Orla
name: O'Flaherty, Joanne
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 39
subject: Education

description: The integration of values into education is a recognized priority globally, with educational systems seeking effective methods to instill and uphold these principles. In the Irish context, the 1998 Education Act mandates that school patrons uphold the ethos, or “characteristic spirit,” synonymous with values. Recently, publicly managed schools in collaboration with Education and Training Boards Ireland (ETBI) embarked on developing a framework to embody sectoral values, outlined in the ETBI Patrons’ Framework on Ethos (2022). To facilitate the enactment of these values, a national community of practice (CoP) network comprising ethos coordinators was established. This paper investigates the experiences of this network, tasked with enacting a value-based framework in Irish publicly managed schools. Through thematic analysis of in-depth semi-structured interviews with ethos coordinators (n = 15), we identified interconnected themes emphasizing Purpose, Praxis, Problems, and Policy (the 4 P’s). Focusing on ethos coordinators experiences, the research delves into their purpose, practical aspects, and challenges. Two discussion themes emerge: Leadership Dynamics in Policy Enactment: Navigating Purpose, Praxis, Problems and Policy and Facilitating Policy Enactment and Strategies for Integration in School Contexts. This study outlines the pivotal role of strategic leadership in linking policy to practice.
title: ÐÐµÑ Ð°Ð½Ð¸Ð·Ð¼Ñ ÑÐ°ÑÑÐµÑÐ½Ð¸Ñ Ð½Ð¾ÑÐ¸ÑÐµÐ»ÐµÐ¹ Ð·Ð°ÑÑÐ´Ð° Ð² Ð¿Ð¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ°Ñ
title: ÑÑÐµÐ±Ð½Ð¾Ðµ Ð¿Ð¾ÑÐ¾Ð±Ð¸Ðµ
titleType: Subtitle
Creators: name: ÐÐ¾ÑÐ¾Ð±ÑÐµÐ², ÐÐµÐ¾Ð½Ð¸Ð´
Publisher: name: ÐÐÐ
Year: 1988
Subjects: ÐÐ¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ¸

description: Ð Ð¿Ð¾ÑÐ¾Ð±Ð¸Ð¸ Ð¾ Ð¿Ð¾Ð¼Ð¾ÑÑÑ ÑÐµÐ¾ÑÐ¸Ð¸ Ð²Ð¾Ð·Ð¼ÑÑÐµÐ½Ð¸Ð¹ Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÑÑÑÑÑ Ð²ÐµÑÐ¾ÑÑÐ½Ð¾ÑÑÑ Ð¸ Ð²ÑÐµÐ¼Ñ ÑÐµÐ»Ð°ÐºÑÐ°ÑÐ¸Ð¸ Ð¸Ð¼Ð¿ÑÐ»ÑÑÐ° Ð´Ð»Ñ Ð¾ÑÐ½Ð¾Ð²Ð½ÑÑ Ð¼ÐµÑÐ°Ð½Ð¸Ð·Ð¼Ð¾Ð² ÑÐ°ÑÑÐµÑÐ½Ð¸Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¾Ð² Ð¸ Ð´ÑÑÐ¾Ðº Ð² Ð¿Ð¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ°Ñ: Ð½Ð° Ð°ÐºÑÑÑÐ¸ÑÐµÑÐºÐ¸Ñ, Ð¿ÑÐµÐ·Ð¾ÑÐ»ÐµÐºÑÑÐ¸ÑÐµÑÐºÐ¸Ñ, Ð´ÐµÑÐ¾ÑÐ¼Ð°ÑÐ¸Ð¾Ð½Ð½ÑÑ Ð¸ Ð¿Ð¾Ð»ÑÑÐ½ÑÑ Ð¾Ð¿ÑÐ¸ÑÐµÑÐºÐ¸Ñ ÐºÐ¾Ð»ÐµÐ±Ð°Ð½Ð¸ÑÑ ÑÐµÑÐµÑÐºÐ¸, Ð¿ÑÐ¸ Ð¿ÑÐ¸Ð¼ÐµÑÐ½Ð¾Ð¼, Ð¼ÐµÐºÐ´Ð¾Ð»Ð¸Ð½Ð½Ð¾Ð¼ Ð¸ ÑÐ»ÐµÐºÑÑÐ¾Ð½-ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½Ð¾Ð¼ ÑÐ°ÑÑÐµÑÐ½Ð¸Ð¸ Ð¸ Ð´Ñ. ÐÑÐ¸ ÑÑÐ¾Ð¼ ÑÑÐ¸ÑÑÐ²Ð°ÐµÑÑÑ ÑÐºÑÐ°Ð½Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð´Ð°Ð»ÑÐ½Ð¾Ð´ÐµÐ¹ÑÑÐ²ÑÑÑÐµÐ³Ð¾ Ð¿Ð¾ÑÐµÐ½ÑÐ¸Ð°Ð»Ð°. ÐÑÐ¾Ð²Ð¾Ð´Ð¸ÑÑÑ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ðµ Ñ ÑÐºÑÐ¿ÐµÑÐ¸Ð¼ÐµÐ½ÑÐ°Ð»ÑÐ½ÑÐ¼Ð¸ ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐ°Ð¼Ð¸. ÐÑÐµÐ´Ð½Ð°Ð·Ð½Ð°ÑÐµÐ½Ð¾ Ð´Ð»Ñ ÑÑÑÐ´ÐµÐ½ÑÐ¾Ð² ÑÐ¿ÐµÑÐ¸Ð°Ð»ÑÐ½Ð¾ÑÑÐµÐ¹ "Ð¤Ð¸Ð·Ð¸ÐºÐ° ÑÐ²ÐµÑÐ´Ð¾Ð³Ð¾ ÑÐµÐ»Ð°", "Ð¤Ð¸Ð·Ð¸ÑÐµÑÐºÐ°Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð¸ÐºÐ°", "Ð¤Ð¸Ð·Ð¸ÐºÐ° Ð¸ ÑÐµÑÐ½Ð¾Ð»Ð¾Ð³Ð¸Ñ Ð¼Ð°ÑÐµÑÐ¸Ð°Ð»Ð¾Ð² Ð¸ ÐºÐ¾Ð¼Ð¿Ð¾Ð½ÐµÐ½ÑÐ¾Ð² ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½Ð¾Ð¹ ÑÐµÑÐ½Ð¸ÐºÐ¸", "ÐÐ¸ÐºÑÐ¾ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½ÑÐµ Ð¸ Ð¿Ð¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ¾Ð²ÑÐµ Ð¿ÑÐ¸Ð±Ð¾ÑÑ", Ð¸Ð·ÑÑÐ°ÑÑÐ¸Ñ ÑÐ¸Ð·Ð¸ÐºÑ ÑÐ²ÐµÑÐ´Ð¾Ð³Ð¾ ÑÐµÐ»Ð°, Ð¿Ð¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ¾Ð², Ð¼ÐµÑÐ°Ð»Ð»Ð¾Ð², ÑÐ¸Ð·Ð¸ÑÐµÑÐºÐ¸Ðµ Ð¾ÑÐ½Ð¾Ð²Ñ Ð¿Ð¾Ð»ÑÐ¿ÑÐ¾Ð²Ð¾Ð´Ð½Ð¸ÐºÐ¾Ð²ÑÑ Ð¿ÑÐ¸Ð±Ð¾ÑÐ¾Ð².
Time Series Experiments and Causal Estimands: Exact Randomization Tests and Trading
Creators: name: Bojinov, Iavor
name: Shephard, Neil
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Ecology
subject: FOS: Biological sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: We define causal estimands for experiments on single time series, extending the potential outcome framework to dealing with temporal data. Our approach allows the estimation of a broad class of these estimands and exact randomization-based p-values for testing causal effects, without imposing stringent assumptions. We further derive a general central limit theorem that can be used to conduct conservative tests and build confidence intervals for causal effects. Finally, we provide three methods for generalizing our approach to multiple units that are receiving the same class of treatment, over time. We test our methodology on simulated “potential autoregressions,” which have a causal interpretation. Our methodology is partially inspired by data from a large number of experiments carried out by a financial company who compared the impact of two different ways of trading equity futures contracts. We use our methodology to make causal statements about their trading methods. Supplementary materials for this article are available online.
title: Ð¡Ð¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ðµ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¹ (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«ÐÐ°ÐºÐ´Ð¾Ð½Ð°Ð»Ð´ÑÂ»)
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÐ°
titleType: Subtitle
Creators: name: ÐÐ°Ð¿Ð¾ÑÐ¾Ð¶ÑÐµÐ½ÐºÐ¾, ÐÐ½Ð°ÑÑÐ°ÑÐ¸Ñ
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2018
Subjects: ÑÐµÐºÐ»Ð°Ð¼Ð½Ð°Ñ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÑ
ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÑÑÐ°ÑÐµÐ³Ð¸Ñ
ÑÑÐ»ÑÐ³Ð¸
ÑÑÐ½Ð¾Ðº Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ

description: Ð¦ÐµÐ»ÑÑ Ð´Ð¸Ð¿Ð»Ð¾Ð¼Ð½Ð¾Ð³Ð¾ Ð¿ÑÐ¾ÐµÐºÑÐ° ÑÐ²Ð»ÑÐµÑÑÑ ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐºÐ° ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¹ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ Ð²Ð½ÑÑÑÐµÐ½Ð½ÐµÐ¹ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¸ ÑÐµÑÑÐ¾ÑÐ°Ð½Ð° Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ. ÐÐ»Ñ Ð´Ð¾ÑÑÐ¸Ð¶ÐµÐ½Ð¸Ñ ÑÐµÐ»Ð¸ Ð±ÑÐ»Ð¸ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÐµÐ¾ÑÐµÑÐ¸ÑÐµÑÐºÐ¸Ðµ Ð°ÑÐ¿ÐµÐºÑÑ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ Ð¿ÑÐµÐ´Ð¿ÑÐ¸ÑÑÐ¸Ð¹ Ð¾Ð±ÑÐµÑÑÐ²ÐµÐ½Ð½Ð¾Ð³Ð¾ Ð¿Ð¸ÑÐ°Ð½Ð¸Ñ Ð¸ Ð¾ÑÐ¾Ð±ÐµÐ½Ð½Ð¾ÑÑÐ¸ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÑÑÐ°ÑÐµÐ³Ð¸Ð¹ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸ ÐÐÐ Â«ÐÐ°ÐºÐ´Ð¾Ð½Ð°Ð»Ð´ÑÂ». Ð¢Ð°ÐºÐ¶Ðµ ÑÐ°ÑÑÐ¼Ð¾ÑÑÐµÐ½Ñ ÑÑÑÐµÑÑÐ²ÑÑÑÐ¸Ðµ Ð¼Ð°ÑÐºÐµÑÐ¸Ð½Ð³Ð¾Ð²ÑÐµ Ð¼ÐµÑÐ¾Ð¿ÑÐ¸ÑÑÐ¸Ñ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¸, Ð¿ÑÐ¾Ð²ÐµÐ´ÐµÐ½ Ð°Ð½Ð°Ð»Ð¸Ð· Ð¸ Ð¾ÑÐµÐ½ÐºÐ° Ð¸Ñ ÑÑÑÐµÐºÑÐ¸Ð²Ð½Ð¾ÑÑÐ¸, Ð¾Ð¿ÑÐµÐ´ÐµÐ»ÐµÐ½Ñ Ð¿ÑÐ¾Ð±Ð»ÐµÐ¼Ñ Ð¸ ÑÑÐ¾ÑÐ¼ÑÐ»Ð¸ÑÐ¾Ð²Ð°Ð½Ñ ÑÐµÐºÐ¾Ð¼ÐµÐ½Ð´Ð°ÑÐ¸Ð¸ Ð¿Ð¾ ÑÐ¾Ð²ÐµÑÑÐµÐ½ÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÐºÐ¾Ð¼Ð¼ÑÐ½Ð¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¹ Ð´ÐµÑÑÐµÐ»ÑÐ½Ð¾ÑÑÐ¸ ÐÐÐ Â«ÐÐ°ÐºÐ´Ð¾Ð½Ð°Ð»Ð´ÑÂ».
Sensitivity Analysis of Electrocardiogram Features to Computational Model Input Parameters
Creators: name: Venton, Jenny
name: Gillette, Karli
name: Gsell, Matthias
name: Loewe, Axel
name: Nagel, Claudia
name: Winkler, Benjamin
name: Wright, Louise
Publisher: name: Institute of Electrical and Electronics Engineers (IEEE)
Year: 2022

description: Cardiac models of electrophysiology capable of generating simulated electrocardiogram (ECG) signals are an increasingly valuable tool for both personalised medicine and understanding cardiac pathologies. Sensitivity analysis (SA) can provide crucial insight into how simulation parameters affect ECG morphology. We use two SA methods, direct numerical evaluation of integrals and polynomial chaos expansion, to calculate main and total effects for ECG features extracted from QRS complexes generated by a cardiac ventricular model. The importance of stimulation site parameters on output ECG features is evaluated. SA methods can highlight and quantify important input parameters for different ECG morphology features, which in some cases can be linked to physiological explanations. For example R peak amplitude in lead II depends on apicobasal location of stimulation sites in the left ventricle. Furthermore, different SA methods have different strengths and weaknesses. Insight into parameter importance supports model development and allows for more nuanced and patient-specific simulation changes.
Bimaximal neutrino mixing and weak complementarity with S4 discrete symmetry
Creators: name: Merlo, Luca
Publisher: name: arXiv
Year: 2009
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The neutrino oscillation data are well explained by the tri-bimaximal pattern. Recently a paper appeared showing that also the bimaximal pattern could be a very good starting point in order to describe the lepton mixing. In this paper I review both the flavour structures and then I present an explicit model based on the discrete symmetry group S4.
description: 4 pages, 1 figure; talk given at SUSY 2009 -- 17th International Conference on Supersymmetry and the Unification of Fundamental Interactions, June 2-4, Boston
title: ÐÐµÐ·Ð¾Ð¿Ð°ÑÐ½Ð¾ÑÑÑ Ð¾Ð¿ÐµÑÐ°ÑÐ¸Ð¾Ð½Ð½ÑÑ ÑÐ¸ÑÑÐµÐ¼. ÐÐ¾Ð´ÐµÐ»Ð¸ ÐºÐ¾Ð½ÑÑÐ¾Ð»Ñ Ð¸ ÑÐ¿ÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ Ð´Ð¾ÑÑÑÐ¿Ð¾Ð¼. Ð§. 1, ÐÐ¸ÑÐºÑÐµÑÐ¸Ð¾Ð½Ð½ÑÐµ Ð¼Ð¾Ð´ÐµÐ»Ð¸
title: Ð»Ð°Ð±Ð¾ÑÐ°ÑÐ¾ÑÐ½ÑÐ¹ Ð¿ÑÐ°ÐºÑÐ¸ÐºÑÐ¼
titleType: Subtitle
Creators: name: ÐÐµÐ³Ð¶Ð´Ð°, ÐÐ¼Ð¸ÑÑÐ¸Ð¹
name: ÐÐ°Ð»Ð¸Ð½Ð¸Ð½, ÐÐ°ÐºÑÐ¸Ð¼
Publisher: name: ÐÐ·Ð´-Ð²Ð¾ Ð¡ÐÐ±ÐÐÐ£
Year: 2003
Subjects: ÐÑÑÐ¸ÑÐ»Ð¸ÑÐµÐ»ÑÐ½ÑÐµ Ð¼Ð°ÑÐ¸Ð½Ñ ÑÐ»ÐµÐºÑÑÐ¾Ð½Ð½ÑÐµ Ð¿ÐµÑÑÐ¾Ð½Ð°Ð»ÑÐ½ÑÐµ

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title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
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Year: 2018
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title: Ð¤Ð¾ÑÐ¼Ñ Ð¸ Ð¼ÐµÑÐ¾Ð´Ñ ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¼Ð°Ð»Ð¾Ð³Ð¾ Ð±Ð¸Ð·Ð½ÐµÑÐ° (Ð½Ð° Ð¿ÑÐ¸Ð¼ÐµÑÐµ ÐÐÐ Â«Ð¡Ð±ÐµÑÐ±Ð°Ð½ÐºÂ»)
title: Ð±Ð°ÐºÐ°Ð»Ð°Ð²ÑÑÐºÐ°Ñ ÑÐ°Ð±Ð¾ÑÐ°
titleType: Subtitle
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Year: 2017
Subjects: ÐºÑÐµÐ´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¼Ð°Ð»Ð¾Ð³Ð¾ Ð±Ð¸Ð·Ð½ÐµÑÐ°
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