cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Pliocene stratigraphy and geology of the Northeastern Ileret Region, Kenya
Creators: name: Kidney, Casey Lee
Publisher: name: University of Utah
Year: 2012
Subjects: Geology - Kenya - Lake Turkana Region
Geology, Stratigraphic - Pliocene

description: Five members of the Koobi Fora Formation: the Lonyumun, Moiti, Lokochot, Tulu Bor, and upper Burgi members, are exposed in Areas 40 and 41 (study area) northeast of Ileret in northern Kenya. Areas 40 and 41 were first mapped using tonal contrasts on aerial photographs by Key and Watkins in their 1988 study, and were not revisited until Gathogo and Brown did a reconnaissance, broadly mapping exposures in their 2006 study. The study area is located on the eastern margin of the Turkana Basin, where the base of the Koobi Fora Formation is in contact with volcanic rocks of Miocene age. Five tuffs are exposed in the study area. Four tuffs occur in the Lonyumun Member: the Guo Tuff, the Kanyeris Tuff, and the newly named Tukunan and Kisemei tuffs. This study, directly or indirectly provides dates for the tuffs in the Lonyumun Member and associated strata by means of magnetostratigraphy and 40Ar/39Ar dating methods. Paleomagnetic sampling and the known dates on the Moiti and Tulu Bor Tuffs of 3.4 and 4.0 Ma respectively, proved invaluable in assigning ages to strata, and was materially helped by an 40Ar/39Ar age of 4.06 ± 0.02 Ma on the Kisemei Tuff. Three tuffs known at many other localities south of the study area, the Lokochot, a-Tulu Bor and Burgi Tuffs, are missing from the study area. Stratigraphic correlations between exposures proved difficult due to numerous and pervasive disconformable surfaces, so that significant time gaps exist in the Lonyumun Member; all of the Moiti Member except the Moiti Tuff is missing, as is all of the lower Burgi Member. Newly discovered fossils in the Lonyumun Member have also been indirectly dated. Initial identification suggests correlation to fossils in the Apak Member at Lothagam southwest of Lake Turkana. In Areas 129 and 130 the Tulu Bor Member is in contact with the Lonyumun Member. Three tuffs, disconformable on the Tulu Bor Tuff allow correlation outside of these areas of which the Aberegaiye Tuff is dated to 2.70 ± 0.02 Ma on alkali feldspars contained in pumices. The other tuffs include a correlate to a tuff in submember D-5 of the Shungura Formation and a correlate to Area 116 to a tuff below the Ninikaa Tuff, the former being the first documented proof for deposition between 2.6-2.0 Ma in the Koobi Fora Formation.
Preanalytic variation in plasma amino acids
Creators: name: Chen, Meng
Publisher: name: University of Utah
Year: 2012
Subjects: Analysis
Separation
Homocystein

description: Plasma amino acid analysis is important for diagnosis and treatment of inborn errors of metabolism, and increasingly for the evaluation of nutritional status and metabolic derangement of other diseases.  Its increasing clinical application is a result of the development of highly sensitive and reliable analytical methods.  The interpretation of plasma amino acids is complicated and requires experience and expertise, not only because of the clinical and analytical complexities, but also because of the preanalytic variation on plasma amino acids.  Many sources of preanalytic variations either remain unknown or are frequently ignored in practice, thus significantly compromising the  usefulness of results.  To better understand the preanalytic variations of plasma amino acids, this study started with review of the literature in current research on preanalytic variation.  Topics included were blood sampling strategies, anticoagulant use, blood separation, deproteinization, storage, hemolysis, and buffy-coat contamination.  This study, then, used both clinical plasma and blood specimens drawn from healthy adult donors to study the effects of delayed separation, hemolysis, and buffy coat contamination on plasma amino acids.  In this study, the ratio of arginine to the sum of arginine and ornithine was discovered to be useful in identifying delayed separation of specimens.  Using this ratio as a tool, the incidence of delayed separation in plasma homocysteine specimens was found to occur frequently.  Effects of hemolysis were found to be variable and complicated by other factors, such as delays in separation, buffy coat contamination, and sample handling at room temperature.  Quantitative determination of hemoglobin by spectrophotometer is simple and can be sued as a marker for assessing plasma sample quality.  Preanalytic variation will continue to be an important issue for plasma amino acid analysis.  The study of it effects will improve the quality of specimens and subsequently generate meaningful results.
The biological role of calcium in adult and neonatal neutrophil chemotaxis.
Creators: name: Coello, Mary Nell Miller
Publisher: name: University of Utah
Year: 2012
Subjects: subject: Immunology
subject: FOS: Clinical medicine
subject: Leukocyte

description: Comparative chemotaxis studies of adult and newborn polymerphonuclear leukocytes (PMNs) were performed by a technique which adapted the micro-pore filter method to a multiwall chamber.  Cord blood neutrophils responded to the chemoattractant FMLP with 60% of adult PMN activity.  In order to investigate the defect of neonatal PMN chemotaxis as a calcium-associated phenomenon, PMNs wre suspended in a calcium-deprived buffer and in the presence of the calcium channel blocker, verapamil, before being assayed for migration.  Adult neutrophils responded to both calcium manipulations with reduced chemotaxis as expected-19% inhibition in calcium-deprived media (p<0.05), and 32% reduction (p<0.001) with 10[-4] M verapamil, Neonatal PMNs, however, increased chemotactic activity in the absence of extracellular calcium-26% (p<0.05) and to a greater extent in the presence of 10[-4] M verapamil (p<0.001).  This suggests that the flux of calcium which occurs upon stimulation of the neutrophil by chemotactic factors may, in fact, be responsible for the neonatal defect and the inhibitory concentrations of intracellular calcium may be present in the neonatal cell.
Sonnenfleckenzeichnung Nr. 23029.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 31.03.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
The effect of visual and auditory coherence on judgments of tranquility to simulated nature experiences
Creators: name: Kim, Jun
Publisher: name: University of Utah
Year: 2015
Subjects: Mental health
Music
Natural environment
Nature
Relaxation
Visual effect

description: Many contemporary work and home environments produce attentional fatigue. One way to recover from such attentional fatigue is to place oneself in environments that promote feelings of tranquility. One way to begin a systematic study of environment-tranquility relations is to frame the research within attention restoration theory (ART). Tranquility is an important experience of restoration and may be evoked by coherence. Coherence refers to environmental arrangements that are structured in such a way that a setting is easy to understand. Visual and auditory coherence can be nested within two emotional genres: one is -pastoral‖ and the other is -sublime.‖ It has been proposed that the level of perceived tranquility may vary according to combinations of different coherences. Therefore, the purpose of this study is to examine the effect of visual and auditory coherence on judgments of tranquility to simulated nature experiences. Participants included 102 students at the University of Utah in summer 2012. Three hypotheses were established and tested using a 1 x 6 repeated measures design. Tranquility was measured using a 7-point 6-item tranquility indicator. Sublime and pastoral photographs of nature were combined with sublime music, pastoral music, and no music, yielding six conditions. Repeated-measures ANOVA yielded significant differences among different combinations of visual and auditory coherence. These results lend support to the notion that less sublime auditory - visual combinations provide tranquil experiences and serve a purpose for people who are seeking a particular natural environment to achieve restorative psychological outcomes. Even though the more sublime combinations garnered comments on increased excitement and enjoyment, this study found that individuals may want to seek out less arousing environments to optimize restorative benefits.
Loci communes
Creators: name: Faesch, Remigius
Publisher: name: [s.n.]
Year: 1600

description: Der Band enthält ursprünglich alle möglichen Exzerpte und Notizen aus den Bereichen Geschichte, Rechtswissenschaft, Länder- und Völkerkunde, Medizin, Alchemie usw. Die zweispaltig angeordneten Eintragungen sind verschiedenen Abteilungen zugeordnet, deren Überschriften mehrheitlich in rot unterstrichenen Majuskeln gehalten sind. Zahlreiche Überschriften und Einträge sind durchgestrichen.
description: Der freie Raum zwischen den Exzerpten ist benützt zu Entwürfen von Briefen Faeschs an verschiedene Empfänger. Inhaltlich die vielseitigste Korrespondenz ist diejenige Faeschs mit (Balthasar de) Monconys aus den Jahren 1641-1646, sie bezieht sich auf neu erschienene Bücher, besonders auf solche mit Porträts und anderen Holzschnitten und Kupferstichen, auf Bildnisse berühmter Männer, auf Kunstblätter, vor allem Albrecht Dürers und seiner Zeitgenossen, auf Gemälde Hans Holbeins, insbesondere solche in Basel in öffentlichem und privatem Besitz (Remigius Faesch, Amerbach), auf Münzen und Medaillen, auf Pflanzen und Sämereien sowie auf den zeitgenössischen Buch- und Kunsthandel. Weitere Adressaten sind u.a.: Heinrich Alers, Aubry, Elias Coriarius, Georg Grob, Daniel Hofer, Samuel Hortin, Christoph Im Hof, Johann Friedrich Jung, Christian von Kettenbach, Ludwig Lingelsheim, Kaspar Lochmann, Heinrich Marstalker, Anton Matthaeus, (Matthaeus) Merian, Mitter, Heinrich Oeri, die Äbtissin Ursula des Stifts Olsberg, Sebastian Ramspeck, Eduard Schleich, Lukas Schreck, Carolus Sponius, Johann Stocker, Johannes Wachmann senior, Johannes Wachmann iunior, Johann Wilhelm Weidenkopf und Alexander Zachariae. Nebst den Briefentwürfen finden sich in dem Band auch Rohfassungen zu Doktordiplomen, zu Einladungen zu Promotionen und anderen Akten der Universität Basel, zu Rechtsgutachten der juristischen Fakultät, zu Prozessschriften und Reden vor Gericht und ähnliches.
description: Remigius Faesch
description: Öffentliche Bibliothek der Universität Basel
description: Lateinisch
description: Aus dem Museum des Remigius Fäsch 1823 in die Universitätsbibliothek gelangt. Vielleicht eines der Pakete von Daniel Hubers Verzeichnis der Handschriften (AR I 16), Fol. Nr. 92: Loci communes.
description: Verzeichnung=Description=Inventaire Dez. 2009 Titel, Entstehungszeit, Sprache, Vorbesitzer, Signatur nach: Binz (1938)
description: Verzeichnung=Description=Inventaire März 2012 Minimalaufnahme nach: Binz (1938)
description: Verzeichnung=Description=Inventaire Sept. 2019 HAN-Katalogisierungsregeln Minimalaufnahme auf der Basis von: Binz (1938) Flury
description: Verzeichnung=Description=Inventaire Dez. 2019 HAN-Katalogisierungsregeln revidiert Müller/Flury
description: Erschliessungsniveau Minimalniveau
Speech handicap index: cross-cultural adaptation and validation in European Portuguese speakers with oral and oropharyngeal cancer
Creators: name: Guimarães, Isabel
name: Sousa, Ana Raquel
name: Gonçalves, Maria Filomena
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: Hematology

description: To date, no valid outcome measure has been developed in European Portuguese (EP) to assess the opinion of the patients with oral and oropharyngeal cancer about the speech impact in his/her related quality of life. This study aimed to cross-culturally adapt the speech handicap index (SHI) in EP and contribute to its validation in oral and oropharyngeal cancer patients. A cross-sectional study was carried out in two phases: (i) SHI translation, back-translation, expert analysis, and pilot study; (ii) application of the EP version of the SHI (EP-SHI) to 95 patients with oral and oropharyngeal cancer and 83 gender- and age-matched healthy individuals. A total of 23 randomly chosen patients were asked to re-fill the EP-SHI questionnaire after 3 weeks. The psychometric properties (feasibility, practicability, reliability, and validity) were assessed. The EP-SHI version brought together expert consensus and the acceptability of 75% of the participants in the pilot study. The EP-SHI questionnaire is feasible (no missing data and floor effect < 7%), practical (an average of 5.5 min to complete), possesses internal consistency reliability (Cronbach’s alpha ≥ 0.90), test-retest reliability (interclass correlation coefficient, ICC ≥ 0.90), significantly strong convergent validity with EP-voice handicap index (VHI) (rô≥0.94), distinguishes patients from healthy speakers and within the patients’ group according to individual speech rating and glossectomy surgery. The EP-SHI is a culturally relevant, valid and reliable patient reported outcome measure (PROM), and therefore, it is appropriate to be recommended for used with oral and oropharyngeal cancer patients.
Sonnenfleckenzeichnung Nr. 22997.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 14.02.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Legge di Drero
Creators: name: De Rossi, Maria Ilaria
Publisher: name: Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

This legal text was situated on the eastern wall of Apollo Delphiniosʼ temple in Dreros, Crete. The inscription is very important: itʼs the oldest law we have from ancient Greece, and itʼs the first in which the word polis appears. The law imposes a limit to the iteration of the kosmos political office, the most important office in Dreros; moreover, the law specifies some punishments in case of violation. There also is an oath to show the importance of this law, and it involves the kosmos, the damioi and the ikati of the polis (we donʼt know the last two offices). The inscription is decently well - preserved, but the particular sequence 󰁢󰁰󰂡󰃁󰂡󰂀󰂡󰁰󰂡󰂐 causes some problems, because its meaning isnʼt clear.

description: Axon
Sonnenfleckenzeichnung Nr. 23056.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 02.05.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel. Es sind Angaben zu Protuberanzen vermerkt
Concentration of acid-fast bacilli with water-insoluble liquids
Creators: name: Fukushima, Taira
Publisher: name: University of Utah
Year: 2012
Subjects: Isolation
Purification

description: 1.  A study of the feasibility of the flotation method for concentrating acid-fast bacilli with water-insoluble, volatile liquids was conducted.  2. Commercial grade n-hexane, manufactured by the Phillips Petroleum Company, was found to have the characteristics of the desired solution.  3. The toxic effect shown by n-hexane was mild to M. phlei, M. smegmatis, BCG and H37Ra.  4. Shaking of he bacillary suspension produced toxic changes in BCG and H37R.  M. phlei and M. smegmatis were not affected by the shaking with n-hexane.  5. Concentration of the bacilli into the n-hexane was achieved with shaking of the bacillary suspension with n-hexane.  6. When the suspension was shaken for 15 seconds and allowed to sit for 30 minutes before inoculation onto media, eugenic growth (5-7 mm) grew readily.  When the suspensions were shaken vigorously for 10 minutes, the size and numbers of the colony diminished.  7. A presumptive diagram of the possible configuration of the tubercle bacilli and the saprophytes is presented.  8. A concept of the pathogenicity of the tubercle bacilli based upon an easter-esterase complex is suggested.
Sonnenfleckenzeichnung Nr. 23024.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 22.03.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
The nature of elder mistreatment in South Korea and implications to improve policy and practice: a qualitative secondary analysis
Creators: name: Kim, Mi Seong
Publisher: name: University of Utah
Year: 2013
Subjects: Older people - Abuse of - Korea (South)

description: To qualitatively explore elder mistreatment occurring within families of South Korea, this study was based on a data set collected during a 1-year period in South Korea through cooperation with the Korean Ministry of Health and Welfare and Korean Elder Protection Agency. For this qualitative secondary analysis, 49 case narratives that met the inclusion criteria were collected from the original data set. The criteria for data collection included: elders aged 65 years or older who were mistreated and who consented to share their stories, abuse by family members, emergency cases, no impairment is evident, and termination of intervention. Based on the existing literature and theories, a comprehensive conceptual framework was developed for better understanding elder mistreatment in families as well as for developing effective, contextually-sensitive intervention and prevention strategies. The conceptual framework has four dimensions: risk factors of elder mistreatment, the nature of violence, the effects on victims, and the victims' responses to elder mistreatment. Particularly, to identify risk factors of elder mistreatment, this study was guided by the ecological perspective. The qualitative secondary analysis revealed the following themes: causes of elder mistreatment, characteristics of violence, damaged personal functioning, broken family relationships, reaction to elder mistreatment, positive perception of public services, dependence upon public support, the changing socioeconomic situation, family iv responsibility, and the ethical dilemmas. In sum, elder mistreatment was associated with not only the characteristics of individuals and families, but also the complicated interactions between individuals and the environmental systems that affect individuals and families. Findings from this study will be useful for giving the practitioners, researchers, policy-makers, and other readers an in-depth understanding of elder mistreatment. Particularly, practitioners, such as social workers, health care providers, and social service providers are in a unique position to have contact with vulnerable elderly and identify whether or not there is violence. Thus, they need to be aware of the nature of elder mistreatment and the diverse contexts surrounding elder mistreatment. This study is also valuable for generating hypotheses and identifying critical areas related to elder mistreatment. Implications for policy, practice, and future research are thoroughly discussed.
Glutaminase-free L-asparaginase production by Leucosporidium muscorum isolated from Antarctic marine-sediment
Creators: name: Freire, Rominne Karla Barros
name: Mendonça, Carlos Miguel Nóbrega
name: Ferraro, Rafael Bertelli
name: Moguel, Ignacio Sánchez
name: Tonso, Aldo
name: Lourenço, Felipe Rebello
name: Santos, João Henrique Picado Madalena
name: Sette, Lara Durães
name: Pessoa, Adalberto
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: L-asparaginase (ASNase) is an essential drug in the treatment of acute lymphoblastic leukemia (ALL). Commercial bacterial ASNases increase patient survival, but the consequent immunological reactions remain a challenge. Yeasts ASNase is closer to human congeners and could lead to lower side effects. Among 134 yeast strains isolated from marine-sediments in King George Island, Antarctica, nine were L-asparaginase producing yeasts and glutaminase-free. Leucosporidium muscorum CRM 1648 yielded the highest ASNase activity (490.41 U.L−1) and volumetric productivity (5.12 U.L−1 h−1). Sucrose, yeast extract and proline were the best carbon and nitrogen sources to support growth and ASNase production. A full factorial design analysis pointed the optimum media condition for yeast growth and ASNase yield: 20 g L−1 sucrose, 15 g L−1 yeast extract and 20 g L−1 proline, which resulted in 4582.5 U L−1 and 63.64 U L−1 h−1 of ASNase and volumetric productivity, respectively. Analysis of temperature, pH, inoculum and addition of seawater indicated the best condition for ASNase production by this yeast: 12–15 °C, pH 5.5–6.5 and seawater >25% (v/v). Inoculum concentration seems not to interfere. This work is pioneer on the production of ASNase by cold-adapted yeasts, highlighting the potential of these microbial resources as a source of glutaminase-free L-asparaginase for commercial purposes.
Ara votiva di Pisistrato il Giovane
Creators: name: Zerbinati, Martina
Publisher: name: Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

The altar of the younger Peisistratos, son of the tyrant Hippias, was known thanks to the historian Thucydides (6.54.6), who provided the text of the inscription and stated that the altar was dedicated by Peisistratos as a memorial of his archonship in Athens during 522/1. Thucydidean dating, however, has been largely debated after the discovery of the Peisistratid Altar of Apollo Pythios in 1877: the controversy is based on epigraphical analysis of the text which judge the letter-forms and the layout as typical of the 5th century B.C. The arguments for an altar much later than 522/1, however, are not completely persuasive because they disclose several anomalies: infact, they seem to be in contradiction with architectural evidence and literacy testimonia; moreover, the presence in Athens of the son of the tyrant after the exile of his father in 511/0 is really problematic.

description: Axon
Sonnenfleckenzeichnung unnummeriert, einen Zürcher Lückentag ergänzend.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 23.03.1969, erstellt von Ahmet Topalbekiroglu an der Universitätssternwarte Istanbul
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Bleistift, erstellt als Zeichnung nach eigener Vorlage am Istanbul Universitesi Observatuari, Beyazit (Istanbul). Instrument: Zeiss Refraktor Teleskop (Öffnung 130 mm, f = 2000 mm, projiziertes Sonnenbild D = 25 cm)
La cd. iscrizione di Lygdamis da Alicarnasso: procedure legali su contese di proprietà
Creators: name: Fabiani, Roberta
Publisher: name: Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

This law was engraved on a stele found at Bodrum, ancient Halikarnassos. It was probably enacted in the second quarter of the 5th century BC in a joint meeting of extraordinary nature syllogos by the two communities of Halikarnasseis and Salmakiteis. The role of the former seems to be prevalent, as suggested by the mention in the prescript of prytanis and neopoios, who also recur as a pair in inscriptions from Halikarnassos dating to the 3rd century BC, respectively as president of the monthly assembly and as eponymous official of the polis. The Lygdamis enacting the law, together with the two communities, must be recognized as the homonymous figure whom the biographical tradition on Herodotus and Panyassis recalls as tyrant of Halikarnassos. Tradition attributed Doric origins to Halikarnassos, nevertheless the document is written in the Ionian language and alphabet. Furthermore, onomastics show a strong Greek-Karian mixture (with the addition of the interesting incidental presence of an Iranian name) both in the community of the Halikarnassians and the Salmakiteis. With its provisions about mnemones, this nomos offers important and controversial evidence on the role of archival documentation in a 5th century BC polis, as well as on the slow transition from an oral culture to one that assigns a more important role to writing and written records. In any case, the context and reasons for the enactment of this law and, in part, its contents, remain elusive. What is certain is that this nomos  occurred at a time of delicate redefinition of property structures. It limited the possibility of resorting to judges to claim property of disputed real estate to within a period of 18 months: during this period, judgments had to be issued on the basis of the testimony of specific mnemones; later, property ownership would have been recognized for those who owned the real estate when those same mnemones were in office, only after pronouncing a liberating oath in the presence of the counterpart. The nomos is protected by a strict entrenchment clause, in which the role of god Apollo emerges. In the case of transgressors, the god is the recipient of the proceeds from the sale of the person or their goods; moreover, it was in his sanctuary that the stele was published.

description: Axon
Sonnenfleckenzeichnung Nr. 22989.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 05.02.1969, erstellt von Werner Scheidegger
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Alleanza tra Lacedemoni ed Etoli Erxadiei
Creators: name: Antonetti, Claudia
Publisher: name: Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

The peace treaty and alliance between the Lacedaemonians and Aetolians Erxadieis is one of the rare specimens of classical Spartan epigraphy and the oldest primary source on the Spartan hegemonic political system: more than being the expression of a direct relationship between Sparta and the Aetolian koinon, the treaty seems to deal with a smaller, unknown ethnos, most probably Peloponnesian, which recalls the Aetolians in its name and origin. On the grounds of its political-institutional language the inscription, whose date in the scholarship fluctuates between the end of the 6th century and 388 BC,  could well be inserted in the Peloponnesian political climate of the years after the Peace of Nicias  and reflect the evolution of international relations at that time; in particular, if Mantinea (restored at l. 4) is excluded from the alliance, the dating can be narrowed down to between 420 and 418 BC.

description: Axon
Production and partial purification by PEG/citrate ATPS of a β-galactosidase from the new promising isolate Cladosporium tenuissimum URM 7803
Creators: name: Paulo, Anderson José
name: de Albuquerque Wanderley, Maria Carolina
name: de Oliveira, Rafael José Vilela
name: dos Santos Vieira, Willie Anderson
name: Alves, Luiz Carlos
name: de Araújo Viana Marques, Daniela
name: Converti, Attilio
name: Porto, Ana Lúcia Figueiredo
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine

description: β-Galactosidase production, partial purification and characterization by a new fungal were investigated. Partial purification was performed by aqueous two-phase system (ATPS) using polyethylene glycol (PEG) molar mass, PEG concentration, citrate concentration and pH as the independent variables. Purification factor (PF), partition coefficient (K) and yield (Y) were the responses. After identification by rDNA sequencing and classification as Cladosporium tenuissimum URM 7803, this isolate achieved a maximum cell concentration and β-galactosidase activity of 0.48 g/L and 462.1 U/mL, respectively. β-Galactosidase partitioned preferentially for bottom salt-rich phase likely due to hydrophobicity and volume exclusion effect caused in the top phase by the high PEG concentration and molar mass. The highest value of PF (12.94) was obtained using 24% (w/w) PEG 8000 g/mol and 15% (w/w) citrate, while that of Y (79.76%) using 20% (w/w) PEG 400 g/mol and 25% (w/w) citrate, both at pH 6. The enzyme exhibited optimum temperature in crude and ATPS extracts in the ranges 35–50 °C and 40–55 °C, respectively, and optimum pH in the range 3.0–4.5, with a fall of enzyme activity under alkaline conditions. Some metal ions and detergents inhibited, while others stimulated enzyme activity. Finally, C. tenuissimum URM 7803 β-galactosidase showed a profile suitable for prebiotics production.
On the mechanism of aconitase.
Creators: name: Speyer, Joseph Frederick
Publisher: name: University of Utah
Year: 2012
Subjects: Metabolism
Mitochondrial

description: Analysis of aconitase kinetics shows that all three substrates, citrate, d(+)-isocitrate, and cis aconitate, are equivalent in the number of slow, rate determining steps in their inter-conversion.  Kinetics and the inhibition studies using deuterium oxide indicate that cis aconitate is not an obligatory intermediate in the citrate:  isocitrate conversion.  The lack of deuterium incorporation from the medium into enzymatically formed citrate from isocitrate shows that conversion to involve and intramolecular hydrogen rearrangement and eliminates cis aconitate as the intermediate.  The proposed mechanism is similar to known intramolecular hydrogen rearrangements, the Whitmore Shift of carbonium ions; It is though that the enzyme can induce carbonium ion formation in the substrate with the aid of ferrous iron.  It is postulated that the metal serves as an electron acceptor or Lewis acid, and that the carbonium ion is formed as a result of coordination of the hydroxyl with the metal. The postulated mechanism accounts for all the reactions of he enzyme and for its kinetic behavior. Aconitase has been prepared from mitochondria by freezing and thawing.  The soluble aconitase is more active than the mitochondrial enzyme in the isocitrate-aconitate and citrate-aconitate reactions, but mitochondrial aconitase is more active in the isocitrate-citrate transformation.  Soluble aconitase showed an optimum at pH 7.3 but mitochondrial aconitase showed optima at pH 5.8 and 7.3.  The isocitrate-aconitate and citrate-aconitate reactions of both soluble and mitochondrial aconitase were inhibited by o-phenanthroline and reactivated by ferrous ions plus ascorbate. Mitochondria incubated with isocitrate retain aconitate.  The data on the intracellular distribution of aconitase were markedly affected by the condition of the assay.
Sonnenfleckenzeichnung Nr. 23000.
Zeichnung von Flecken und Fackelflächen zur Ermittlung der Sonnenaktivität am 19.02.1969, erstellt von Fritz Riesen
Creators: name: [s.n.]
Publisher: name: [s.n.]
Year: 1969

description: Bleistiftzeichnung mit Tinte und Farbstift überschrieben, erstellt als Projektionsbildzeichnung in der Eidgenössischen Sternwarte Zürich. Instrument: Zeiss Coudé-Refraktor (150/2250 mm).
Die Beobachtungen zu Einzelflecken und zu Sonnenfleckengruppen wurden mit Bleistift auf einem Vordruck eingetragen. Später wurden ergänzende Angaben aufgrund auswärtiger Beobachtungen direkt auf der Fleckenzeichnung hinzugefügt. Zusätzlich notiert: Tabelle mit statistischen Angaben – mit Vermerk der Werte Gr, f und g, wobei die Bestimmung der Fleckenrelativzahl nach wie auf visueller Beobachtung und anderer Instrumentierung beruhte (und dafür das entsprechende Registerblatt (in Teilbestand acht) ausgefüllt wurde). Zusammen mit den täglichen Werten oft Angabe der Resultate der Flächenmessungen der Flecken (F und F -o) in Millionsteln der Scheibe bzw. der Halbkugel
Effective nuclear delivery of therapeutic molecules
Creators: name: Mishra, Deepa
Publisher: name: University of Utah
Year: 2012
Subjects: Dexamethasone
Gene delivery
Layer-by-layer
Micelle
PLGA
Polyethylenimine

description: Many strides have been made towards utilizing gene therapy to treat genetic disorders in humans. Low gene expression and formulation stability during storage have hindered the use of nonviral carriers thus far. The purpose of this research was to develop a cationic PLGA-b-bPEI micelle-based delivery system to co-deliver genes and small therapeutic drugs to the cell nucleus that could also be lyophilized for long-term storage and reconstituted as needed by simply adding water. Several PLGA-b-bPEI copolymers were synthesized and characterized for their potential to form reconstitutable micelle-based gene therapeutic delivery systems that showed enhanced nuclear delivery over other current cationic nonviral delivery systems.  The first section of this dissertation addresses the characterization of a reconstitutable charged polymeric micelle system to assess its suitability for gene therapeutics delivery. A PLGA-b-bPEI block copolymer was synthesized and characterized for buffering capacity, particle size, zeta potential, complexation ability, cytotoxicity, transfection efficiency and reporter gene expression, and retention of physicochemical and biological characteristics upon lyophilization and reconstitution. Results showed that micelles and micelle/pDNA complexes retained their physicochemical characteristics following lyophilization and reconstitution. Transfection levels were enhanced using reconstituted complexes compared to their fresh counterparts without significant cellular toxicity even with pDNA doses up to 20?g, and transfection increased linearly with increasing pDNA dose.  The second section of this dissertation investigates the use of dexamethasone-loaded micelles for enhanced nuclear accumulation of a reporter gene. PLGA-b-bPEI polymers synthesized in the first section were used to prepare dexamethasone-loaded micelles and complexed with pDNA. Gene expression was significantly enhanced using dexamethasone-loaded micelle/pDNA complexes compared to blank micelle/pDNA complexes, particularly for complexation weight ratios less than 1. Dex-micelles achieved gene expression equivalent to the blank system using a fraction of the polymer (weight ratio 0.25 versus 1), indicating that dexamethasone increased nuclear accumulation of polyplexes. Gene expression was nearly equivalent to a bPEI control carrier, leading to future plans of co-loading the micelle system with other types of drugs and examining this system's suitability for specific applications such as treating patients suffering from asthma or other inflammatory diseases where dexamethasone treatment could be additionally beneficial for its anti-inflammatory properties.
Decreto concernente la terra sacra del santuario di Eleusi
Creators: name: De Martinis, Livia
Publisher: name: Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

The decree concerns the sacred land (ἱερὰ ὀργάς) of the sanctuary of Demeter and Kore at Eleusis and focuses on two related but distinct issues: the definition of the boundaries of the sacred land and the possibility for the future of renting and farming - or of not renting and leaving fallowed - the land immediately beyond the boundaries of the sacred land and already cultivated in the past. The decree is an important document in many respects. First of all it attests the disputes between Athens and Megara for the control of the Eleusinion’s sacred land, adding to the accounts of the attidographers Philochorus and Androtion and referring to the existence of a former decree connected to the sacred land and proposed by a certain Philocrates. Moreover, it confirms the existence of the practice of renting the sacred land in mid-fourth century BC – mentioned in other contemporary inscriptions and urged by Xenophon in his Poroi. It also offers some useful elements for the dating of the Eleusinion’s restoration works. Finally, it provides evidence for the consultation of the Delphic oracle and sheds light on Athenian democratic procedure in the middle of the 4th century BC.

description: Axon
An instrumentalist approach to validation: a quantitative assessment of a novel coal gasification model
Creators: name: Reid, Charles Martin
Publisher: name: University of Utah
Year: 2012
Subjects: Coal
DQMOM
Instrumentalism
LES
Simulation
Validation

description: The explosion in computing power and its application to complex multiphysics problems has led to the emergence of computer simulation as a new way of extending the inductive methods of science. Many fields, particularly combustion, have been greatly changed by the ability of simulation to explore in great detail the implications of theories. But problems have also arisen; a philosophical foundation for establishing belief in simulation predictions, particularly important for complex multiphysics systems where experimental data are sparse, is sorely lacking. Toward the end of establishing such a foundation, a comprehensive philosophical approach to model validation, called instrumentalism, is proposed.  A framework for verification and validation/uncertainty quantification (V&V/UQ) of codes is presented in detail, and is applied to a novel entrained flow coal gasification  model implemented in the massively parallel simulation tool Arches. The V&V/UQ process begins at the mathematical model. The novel coal gasification model, which utilizes the direct quadrature method of moments (DQMOM) for the solid phase and large eddy simulation (LES) for the gas phase and accounts for coupling between the gas and solid phases, is described in detail. A verification methodology is presented in the larger context of validation and uncertainty quantification, and applied to the Arches coal gasification model.  A six-step validation framework is adopted from the literature and applied to the validation of the Arches gasification model. One important aspect of this framework is model reduction, creating surrogate models for complex and expensive multiphysics  simulators. A procedure for constructing surrogate response surface models is applied to the Arches gasification model, with several statistical analysis techniques used to determine the goodness of fit of the coal gasification response surface.  This response surface is then analyzed using two methods: the Data Collaboration methodology, an approach from the literature; and a Monte Carlo analysis of the response surface. These analyses elucidate regions of parameter space where the simulation  tool makes valid predictions. The Monte Carlo analysis also yields probabilities of simulation validity, given input parameter values. These probabilities are used to  construct a prediction interval, which can then be used to compute the probability of a consistent simulation prediction.
Decreto onorario ateniese per la città di Eleunte
Creators: name: Fogagnolo, Marta
Publisher: name: Università Ca’ Foscari Venezia, Italia
Year: 2017

description:

In the forties of the IVth century BC the Chersonesos was simultaneously at the centre of the military interests of Athens and of the expansionism of Philip II. The first strenghtened its presence on the region through the cleruchs and the sending of the general Cares. The honorary decree for Elaeus, member of the Second Athenian League, testifies the Athens’attempt to reinforce the alliance and the controll on the area. The benefits granted include the protection of Cares and the regulation of the relations between the local community and the Athenian cleruchs.

description: Axon
Production and partial purification by PEG/citrate ATPS of a β-galactosidase from the new promising isolate Cladosporium tenuissimum URM 7803
Creators: name: Paulo, Anderson José
name: de Albuquerque Wanderley, Maria Carolina
name: de Oliveira, Rafael José Vilela
name: Vieira, Willie Anderson dos Santos
name: Alves, Luiz Carlos
name: de Araújo Viana Marques, Daniela
name: Converti, Attilio
name: Porto, Ana Lúcia Figueiredo
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biophysics
subject: Biochemistry
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine

description: β-Galactosidase production, partial purification and characterization by a new fungal were investigated. Partial purification was performed by aqueous two-phase system (ATPS) using polyethylene glycol (PEG) molar mass, PEG concentration, citrate concentration and pH as the independent variables. Purification factor (PF), partition coefficient (K) and yield (Y) were the responses. After identification by rDNA sequencing and classification as Cladosporium tenuissimum URM 7803, this isolate achieved a maximum cell concentration and β-galactosidase activity of 0.48 g/L and 462.1 U/mL, respectively. β-Galactosidase partitioned preferentially for bottom salt-rich phase likely due to hydrophobicity and volume exclusion effect caused in the top phase by the high PEG concentration and molar mass. The highest value of PF (12.94) was obtained using 24% (w/w) PEG 8000 g/mol and 15% (w/w) citrate, while that of Y (79.76%) using 20% (w/w) PEG 400 g/mol and 25% (w/w) citrate, both at pH 6. The enzyme exhibited optimum temperature in crude and ATPS extracts in the ranges 35–50 °C and 40–55 °C, respectively, and optimum pH in the range 3.0–4.5, with a fall of enzyme activity under alkaline conditions. Some metal ions and detergents inhibited, while others stimulated enzyme activity. Finally, C. tenuissimum URM 7803 β-galactosidase showed a profile suitable for prebiotics production.
Glutaminase-free L-asparaginase production by Leucosporidium muscorum isolated from Antarctic marine-sediment
Creators: name: Freire, Rominne Karla Barros
name: Mendonça, Carlos Miguel Nóbrega
name: Ferraro, Rafael Bertelli
name: Moguel, Ignacio Sánchez
name: Tonso, Aldo
name: Lourenço, Felipe Rebello
name: Santos, João Henrique Picado Madalena
name: Sette, Lara Durães
name: Junior, Adalberto Pessoa
Publisher: name: Taylor & Francis
Year: 2020
Subjects: subject: Biochemistry
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: L-asparaginase (ASNase) is an essential drug in the treatment of acute lymphoblastic leukemia (ALL). Commercial bacterial ASNases increase patient survival, but the consequent immunological reactions remain a challenge. Yeasts ASNase is closer to human congeners and could lead to lower side effects. Among 134 yeast strains isolated from marine-sediments in King George Island, Antarctica, nine were L-asparaginase producing yeasts and glutaminase-free. Leucosporidium muscorum CRM 1648 yielded the highest ASNase activity (490.41 U.L−1) and volumetric productivity (5.12 U.L−1 h−1). Sucrose, yeast extract and proline were the best carbon and nitrogen sources to support growth and ASNase production. A full factorial design analysis pointed the optimum media condition for yeast growth and ASNase yield: 20 g L−1 sucrose, 15 g L−1 yeast extract and 20 g L−1 proline, which resulted in 4582.5 U L−1 and 63.64 U L−1 h−1 of ASNase and volumetric productivity, respectively. Analysis of temperature, pH, inoculum and addition of seawater indicated the best condition for ASNase production by this yeast: 12–15 °C, pH 5.5–6.5 and seawater >25% (v/v). Inoculum concentration seems not to interfere. This work is pioneer on the production of ASNase by cold-adapted yeasts, highlighting the potential of these microbial resources as a source of glutaminase-free L-asparaginase for commercial purposes.