cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Micromechanics of Epithelial tissue-inspired structures
Creators: name: Kulkarni, Tejas Ravindra
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Biomaterials
Mechanical engineering not elsewhere classified

description: Epithelial tissues, one of the four primary tissue structures found in our human body, are known to comprise of tiny cells interconnected in a unique continuous pattern. In most cases, they serve a dual purpose of protecting the internal organs from physical damage, and at the same time, enable in facilitating inter-cellular activities and prevent pathogen break ins. While the tissue mechanics and its proliferation have been scrutinized to great detail, it is their geometric uniqueness, that has remained more or less unexplored. With an intent of doing the same, this thesis identifies and explores those geometric properties/parameters that have an influence on the micro structure’s homogenized and localized response. However, it does so by extracting the microstructures profile and representing its cell edges via three dimensional beam elements - hence the name, bio-inspired structures. The analysis is carried out by first developing a staggered Representative Volume Element (RVE)using finite elements, and identifying its appropriate size. The staggered assembly aids in minimizing boundary effects from creeping in, and at the same time, provides the requisite statistical homogeneity. This is followed by the geometry study. A wide range of epithelial geometries are considered for the study, ranging from completely isotropic skin models, to in plane anisotropic cuboidal structures and out of plane anisotropic stratified geometries. The effects of orientation, relative density and edge length are extracted and studied in great detail. It is observed that cell edges initial orientation has a direct dependence on the particle distribution, whereas the change in orientation is largely dependent on the deformation the microstructure is subjected to. Relative density is documented to show a direct correlation to a materials homogenized response i.e. larger the relative density, greater is the microstructures stiffness and homogenized stress response to the same deformation. Edge length, on the other hand is observed to showcase a downward trend on the cell edge’s axial stress. On average, in any kind of distribution and any kind of deformation, smaller cell edges are known to showcase larger stresses, as compared to the larger cell edges.
sj-docx-1-soe-10.1177_00380407211048453 – Supplemental material for Intensive Mothering and the Unequal School-Search Burden
Creators: name: Brown, Bailey A.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Education
subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-soe-10.1177_00380407211048453 for Intensive Mothering and the Unequal School-Search Burden by Bailey A. Brown in Sociology of Education
ION MOBILITY AND GAS-PHASE COVALENT LABELING STUDY OF THE STRUCTURE AND REACTIVITY OF GASEOUS UBIQUITIN IONS ELECTROSPRAYED FROM AQUEOUS AND DENATURING SOLUTIONS
Creators: name: Carvalho, Veronica Vale
Publisher: name: Purdue University Graduate School
Year: 2022
Subjects: Analytical biochemistry

description: Gas-phase ion/ion covalent modification was coupled to ion mobility/mass spectrometry analysis to directly correlate the structure of gaseous ubiquitin to its solution structures with selective covalent structural probes. Collision cross section (CCS) distributions were measured prior to ion/ion reactions to ensure the ubiquitin ions were not unfolded when they were introduced to the gas phase. Ubiquitin ions were electrosprayed from aqueous and methanolic solutions yielding a range of different charge states that were analyzed by ion mobility and time-of-flight mass spectrometry. Aqueous solutions stabilizing the native state of ubiquitin generated folded ubiquitin structures with CCS values consistent with the native state. Denaturing solutions favored several families of unfolded conformations for most of the charge states evaluated. Gas-phase covalent labeling via ion/ion reactions was followed by collision induced dissociation of the intact, labeled protein to determine which residues were labeled. Ubiquitin 5+ and 6+ electrosprayed from aqueous solutions were covalently modified preferentially at the lysine 29 and arginine 54 residues, indicating that elements of secondary structure as well as tertiary structure were maintained in the gas phase. On the other hand, most ubiquitin ions produced in denaturing conditions were labeled at various other lysine residues, likely due to the availability of additional sites following methanol and low pH-induced unfolding. These data support the conservation of ubiquitin structural elements in the gas phase. The research presented here provides the basis for residue-specific characterization of biomolecules in the gas phase
TEMPERATURE-DEPENDENT OPTICAL PROPERTIES CHANGES OF THIN FILMS AND MODELING USING APPLICABLE ELLIPSOMETRY NEAR IR REGION
Creators: name: Lee, Changkyun
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Electrical engineering not elsewhere classified

description: Thin films with selective spectral properties have great potential for use in applications such as solar thermal absorbers, selective thermal emitters, thermal barrier coatings, and thermophotovoltaics. Understanding the dependence of their optical properties with temperature is crucial for practical applications. Relatively less-used films with high thermal stability, high refractive index, and infrared transparency, such as cerium oxide CeO2 and magnesium oxide (MgO) have not been studied extensively for high-temperature applications. In this paper, CeO2, MgO, and several multilayer samples containing these compounds will be studied their change of optical properties with increasing temperature across the visible and infrared spectrum. In this work, I introduce Spectroscopic Ellipsometry (SE) to analyze dielectric constants of films and measure its thickness at multiple incident angles in visible and near-Infrared (IR) wavelengths both at room temperature and elevated temperatures. Using ellipsometry, several single and multilayer thin films (CeO2 and other transparent materials-based) have been measured their dielectric constants and thickness at room temperature and high temperature up to 500°C using thermal control stages called INSTEC. The change of their optical properties with temperatures has been characterized using theoretical modelling. Fitting their optical properties have been observed by changing thickness of each layer and calculating the corresponding Cauchy parameters in transparent material. Finally, FTIR measurements will be used to further characterize direct emission of these films at higher temperatures. This will be performed at room temperature and high temperature up to 1400 °C.
sj-pdf-1-sms-10.1177_20563051211047545 – Supplemental material for The Longitudinal Dimension of Social-Mediated Movements: Hidden Brokerage and the Unsung Tales of Movement Spilloverers
Creators: name: Zhou, Alvin
name: Yang, Aimei
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 200199 Communication and Media Studies not elsewhere classified
subject: FOS: Media and communications

description: Supplemental material, sj-pdf-1-sms-10.1177_20563051211047545 for The Longitudinal Dimension of Social-Mediated Movements: Hidden Brokerage and the Unsung Tales of Movement Spilloverers by Alvin Zhou and Aimei Yang in Social Media + Society
sj-pdf-1-sjs-10.1177_14574969211042457 – Supplemental material for The impact of cirrhosis on the postoperative outcomes of patients undergoing splenectomy: Propensity score matched analysis of the 2011–2017 US hospital database
Creators: name: Lee, David U.
name: Fan, Gregory H.
name: Hastie, David J.
name: Addonizio, Elyse A.
name: Karagozian, Raffi
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110323 Surgery
subject: FOS: Clinical medicine

description: Supplemental material, sj-pdf-1-sjs-10.1177_14574969211042457 for The impact of cirrhosis on the postoperative outcomes of patients undergoing splenectomy: Propensity score matched analysis of the 2011–2017 US hospital database by David U. Lee, Gregory H. Fan, David J. Hastie, Elyse A. Addonizio and Raffi Karagozian in Scandinavian Journal of Surgery
sj-pdf-1-ccx-10.1177_10732748211043665 – Supplemental Material for Impact of Surgical Margin Status on Survival in Gastric Cancer: A Systematic Review and Meta-Analysis
Creators: name: Jiang, Zhiyuan
name: Liu, Chunyu
name: Cai, Zhaolun
name: Shen, Chaoyong
name: Yin, Yuan
name: Yin, Xiaonan
name: Zhao, Zhou
name: Mu, Mingchun
name: Yin, Yiqiong
name: Zhang, Bo
Publisher: name: SAGE Journals
Year: 2021
Subjects: Oncology and Carcinogenesis not elsewhere classified

description: Supplemental Material, sj-pdf-1-ccx-10.1177_10732748211043665 for Impact of Surgical Margin Status on Survival in Gastric Cancer: A Systematic Review and Meta-Analysis by Zhiyuan Jiang, Chunyu Liu, Zhaolun Cai, Chaoyong Shen, Yuan Yin, Xiaonan Yin, Zhou Zhao, Mingchun Mu, Yiqiong Yin and Bo Zhang in Cancer Control
sj-docx-1-qjp-10.1177_17470218211048317 – Supplemental material for Emotion perception bias associated with the hijab in Austrian and Turkish participants
Creators: name: Korb, Sebastian
name: Deniz, Tugba Ceren
name: Ünal, Bengi
name: Clarke, Alasdair
name: Silani, Giorgia
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology

description: Supplemental material, sj-docx-1-qjp-10.1177_17470218211048317 for Emotion perception bias associated with the hijab in Austrian and Turkish participants by Sebastian Korb, Tugba Ceren Deniz, Bengi Ünal, Alasdair Clarke and Giorgia Silani in Quarterly Journal of Experimental Psychology
sj-pdf-1-pic-10.1177_09544062211027200 - Supplemental material for Dimensional optimization of rocker-bogie suspension for planetary rover based on kinetostatics and terramechanics
Creators: name: Li, Jie
name: He, Jun
name: Xing, Yan
name: Gao, Feng
Publisher: name: SAGE Journals
Year: 2021
Subjects: Engineering not elsewhere classified

description: Supplemental material, sj-pdf-1-pic-10.1177_09544062211027200 for Dimensional optimization of rocker-bogie suspension for planetary rover based on kinetostatics and terramechanics by Jie Li, Jun He, Yan Xing and Feng Gao in Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science
sj-docx-1-tej-10.1177_20417314211044855 – Supplemental material for Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells
Creators: name: Born, Gordian
name: Nikolova, Marina
name: Scherberich, Arnaud
name: Treutlein, Barbara
name: García-García, Andrés
name: Martin, Ivan
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences

description: Supplemental material, sj-docx-1-tej-10.1177_20417314211044855 for Engineering of fully humanized and vascularized 3D bone marrow niches sustaining undifferentiated human cord blood hematopoietic stem and progenitor cells by Gordian Born, Marina Nikolova, Arnaud Scherberich, Barbara Treutlein, Andrés García-García and Ivan Martin in Journal of Tissue Engineering
Investigation of Surfactant Aggregation in Solutions and at the Calcite/Water Interface
Creators: name: Bhat, Anuradha
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Environmental engineering not elsewhere classified

description: Surfactants self-assemble into diverse aggregate structures like micelles and bilayers. These aggregates play a vital role in applications ranging from wastewater treatment to soil remediation to carbon utilization. Therefore, an understanding of aggregate morphologies in solutions and at interfaces allows us to tailor surfactants for specific applications. To that end, we have used molecular dynamics (MD) simulations to glean atomic-level insights into surfactant aggregation.First, we focus on the self-assembly of Aerosol-OT (AOT), a double-tailed anionic surfactant in aqueous media. Through extensive classical MD simulations, AOT morphologies are generated that are consistent with experimental phase diagrams. Aggregates range from spherical micelles at low concentrations (1 wt.%) to bilayers at higher concentrations (20 wt.%). A transitional biphasic regime is identified at an intermediate concentration (7.2 wt.%); this regime comprises prolate spheroidal and long rod-like micelles. Metrics of micelle shape and size are computed from the moments of inertia tensor. The polydispersity in these metrics are also quantified. The bilayer thickness and area per AOT head group agree with experimental measurements. The simulations also reveal atomic-level mechanistic insights into the early stages of surfactant aggregation. Taken together, these simulations elucidate the structural diversity of AOT aggregates as a function of concentration and temperature thus being complementary to mean-field experiments.Second, we attempt to understand the role of AOT in the valorization of carbon dioxide to calcium carbon ultrafine particles. Through an enhanced sampling MD technique called umbrella sampling, the interactions between a single molecule of AOT and the (10m14) crystal plane of CaCO3 are investigated. These simulations are complemented by a first principles Density Functional Theory (DFT) analysis which is performed through collaboration. DFT identifies the most stable adsorption configurations for AOT-like surrogate molecules and unravels the nature of chemical bonds between these molecules and the (10m14) crystal plane.Finally, preliminary experimental studies pertaining to the synthesis of CaCO3 particles using CO2 and surfactants is discussed. The CaCO3 particles are characterized using X-ray diffraction, scanning electron microscopy, and Raman spectroscopy. The influence of the nature of the surfactant; anionic AOT, or cationic cetyl trimethylammonium bromide (CTAB), on the morphology of CaCO3 particles is discussed.
Additional file 8 of Association between diastolic blood pressure during the first 24 h and 28-day mortality in patients with septic shock: a retrospective observational study
Creators: name: Gao, Zhiwei
name: Li, Cong
name: Chen, Hui
name: Chen, Dongyu
name: Ma, ShaoLei
name: Xie, Jianfeng
name: Wu, Changde
name: Liu, Ling
name: Yang, Yi
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Additional file 8. Subgroup analysis of the association between 28 day survival and mDBP24h mSBP24h and mMAP24h in septic shock patients.
Disentangled Representations Learning for Covid-19 Sequelae Prediction
Creators: name: Liu, Zhaorui
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Applied computing not elsewhere classified
Health informatics and information systems

description: Severe acute respiratory syndrome (SARS)-CoV-2 emerged in late 2019, then became an unprecedented public health crisis. Hundreds of millions of people have been affected. What is worse, many researchers have revealed that COVID-19 may have long-term effects on varieties of organs even after recovery. Consequently, there is a need for the study of its sequelae. The purpose of this project is to use machine learning algorithms to study the relationship between patients’ EMR data and long-term sequelae, especially kidney diseases. Inspired by a recent learning disentangled representation for recommendation work, this project proposes a method that (i) predicts the development trend of the kidney disease; (ii) learn representations that uncover and disentangle factors related to kidney diseases. The major contribution is that this model has high interpretability which enables medical works to infer the development of patients' condition.
EXPERIMENTAL APPROACH FOR ANALYZING SURFACE AND INTERFACIAL PROPERTIES OF POLYMERS
Creators: name: Jo, Hyungyung
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Materials engineering not elsewhere classified

description: The surface and interfacial properties of polymers are of great importance for many applications, such as coatings, thin films, abrasives, fillers, and adhesives. The molecular structure at surfaces and interfaces are different from those in the bulk, which can lead to an abnormal phenomenon in a certain environmental condition. When implementing newly developed materials into industrial systems, it is crucial to characterize the materials’ properties to determine the materials’ lifespan and avoid any safety problems, especially for applications requiring long-term working conditions. Mechanical and chemical factors primarily influence the mechanical and chemical performance of materials at surfaces or the interfaces. A variety of testing tools have been developed over decades to characterize the mechanical and chemical properties of polymers. However, as industry needs grow and new technology facilitates various forms of materials advancement, understanding surface and interfacial properties of the materials becomes more challenging. Additionally, although some materials have been commonly utilized in industry or our daily lives for a long time, standardized evaluation protocols have not been developed yet. Thus, the work in this dissertation investigates the surface or interfacial properties of various materials already being used or potentially used in many applications using various experimental approaches. The first study examines the mechanical properties of glassy-rubbery polymer blend thin films under uniaxial strain. A recently developed mechanical characterization technique utilizing buckling instabilities was employed to analyze how the blend thin films deform and fail as a function of the ratios of blend polymers used. The second study discusses how the intrinsic properties of thermoplastic pavement marking materials (PPMs) affect adhesion on road surfaces in various environmental conditions. In order to investigate the interfacial performance of PPMs on asphalt, a shear adhesion test is developed. The third study investigates a model of thermal interface materials (TIMs) in thermal cycling and aging conditions. A computational method was also utilized to define a potential thermal degradation mechanism. Lastly, the fourth study measures surface damages on general polymeric materials from simulated routine disinfectant processes. By using various spectroscopic and microscopic characterization tools, the effect of surface damages on bacterial activity is analyzed.
THE EFFECTS OF NOISE ON AUTONOMIC AROUSAL AND ATTENTION AND THE RELATIONSHIP TO AUTISM SYMPTOMATOLOGY
Creators: name: Alvar, Ann Marie
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Other health sciences not elsewhere classified
Sensory processes, perception and performance

description: Experiment One: The Effect of Noise on Autonomic Arousal
In response to the growing demand for research that helps us understand the complex interactions between Autonomic Arousal (AA) on behavior and performance there is an increasing need for robust techniques to efficiently utilize stimuli, such as sound, to vary the level of AA within a study. The goal of this study was to look at the impact of several factors, including sound intensity, order of presentation, and direction of presentation on skin conductance level, a widely utilized technique for approximating levels of AA. To do this we had 34 young adults ages 18- 34 listen to a series of 2-minute blocks of a sound stimuli based off a heating, ventilation, and air conditioning system (HVAC). Blocks included 5 single intensity conditions each block differing in 10 dBA steps ranging from 35-75 dBA. We presented blocks in both rising and falling level of intensity, with half the participants hearing them in a rising order first and half in a falling order first. The evidence found by this study suggests that increasing the sound level plays an important role in increasing AA and habituation is an extremely important factor that must be accounted for as it, in the case of typical young adults, quickly dampens the response to stimuli and subsequent stimuli. These findings suggest that researchers can best efficiently maximize the range of AA they can use while keeping their participants comfortable by starting out with the most intense stimuli and proceeding to the less intense stimuli, working with habitation instead of against it.
 Experiment Two: The Effect of Autonomic Arousal on Visual Attention
The goal of this study was to better understand how various levels of autonomic arousal impact different components of attentional control and if ASD-related traits indexed by Autism Quotient scores (AQ) might relate to alterations in this relationship. This study had 41 young adult participants (23 women, 17 men, 1 prefer not to say), ages ranging from 18 to 38 years old. Participants listened to varying levels of noise to induce changes in AA, which were recorded as changes in skin conductance level (SCL). To evaluate attentional control, participants preformed pro and anti-saccade visual gap–overlap paradigm tasks as measures of attentional control. The findings of this study suggest that increased levels of autonomic arousal are helpful for improving performance on anti-saccade tasks, which are heavily dependent on top-down attentional control. Additionally, increases in AQ scores were related to having less of a benefit from increasing levels of arousal on anti-saccade tasks. Additional interactions were also found and are discussed in this paper.
Additional file 5 of Association between diastolic blood pressure during the first 24 h and 28-day mortality in patients with septic shock: a retrospective observational study
Creators: name: Gao, Zhiwei
name: Li, Cong
name: Chen, Hui
name: Chen, Dongyu
name: Ma, ShaoLei
name: Xie, Jianfeng
name: Wu, Changde
name: Liu, Ling
name: Yang, Yi
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Additional file 5. The relationship between the duration different mDBP24h levels and 28-day mortality of septicshock patients.
Writing with Letterpress: A Case Study for Research on Human-Technology Interaction
Creators: name: Cook, Devon S
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Technical writing
Professional writing and journalism practice
Creative arts, media and communication curriculum and pedagogy
Design not elsewhere classified
Philosophy of language
Science, technology and engineering curriculum and pedagogy

description: This research uses the composition practices of three experienced letterpress typesetters as a case study for the development of a methodology for studying human-technology interaction. This methodology tries to take seriously the implications that theories of materiality have for empirical research in writing and technology. Data was collected from three experienced typesetters, each of whom was observed setting type for two hours, then interviewed for 1 ½ to 2 hours, using observation footage to inform interview questions. Interview transcripts and observation footage were then coded for observable material intra-actions and the influences that characterized those actions and brought them into being. Data analysis produced six desiderata, or desires for design, that emerged as driving the composition process: 1) a desire to use the technology, 2) a desire for efficiency, 3) a desire to imitate/defer to historical practices, 4) a desire for letter-level correctness, 5) attention to aesthetics, and 6) a desire to communicate.
CHARACTERIZATION OF MOCK PLASTIC-BONDED ENERGETIC MATERIALS UNDER CYCLIC COMPRESSION AT LOW STRAIN RATES
Creators: name: Petri, Trevor S
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Mechanical engineering not elsewhere classified

description: This work seeks to characterize the mechanical response and material properties of polymer-bonded energetic materials (PBXs) when acted upon by a low-frequency, high-amplitude excitation. These particle-binder composites have been shown to incur damage when samples are deformed, even down to around 0.01% strain, via a phenomenon known as the Mullins effect. The presence of damage in PBX materials has been shown to erratically inhibit performance. By garnering an understanding for how energetic materials respond to a mechanical excitation, a better prediction of the material properties can be made. The goal of this research was to experimentally measure energy dissipation in mock energetic materials and then use a constitutive model based in Ogden hyperelasticity and yield-surface-free endochronic plasticity to determine material properties from the experimental data. Cyclic compression tests were performed in order to produce low-frequency, high-amplitude, mechanical excitation, and stress relaxation tests were carried out to determine steady-state, stress relaxation times under a constant strain. The cyclic compression test results were then passed through the constitutive model to reproduce stress data and estimate material parameters that describe stress-softening, stiffness, and damage. The end goal of this research is to begin connecting the research related to quasi-static uniaxial loading experiments with frequency-based studies.It should be noted that low-frequency, high-amplitude cyclic compression of energetic materials has yet to be thoroughly explored. For example, continuum mechanic studies report a connection of strain rate to stress response, but given their steady-state nature, they do not account for material damage that occurs over time, which is pivotal in understanding how a material may act when a variable force with respect to time is placed on the material. Forcing, such as a simple sinusoidal excitation or a general white noise excitation, can yield differing results over the duration of the test. The work described here takes the findings of similar materials and continues on by determining the transient response when a variable, cyclic force is enacted on a specimen in order bridge the gap between unidirectional compression and frequency-dependent mechanical excitation.
ESSAYS ON HEALTH CLAIMS DATA-ENABLED COMBAT OF CURRENT OPIOID EPIDEMIC
Creators: name: Valencia, Carolina Vivas
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Biomechanical engineering

description: Health care has become a data-intense industry with billions of data generated at numerous healthcare encounters on a daily basis through wearable devices, medical images, and from biomedical and biobehavioral research studies. These data are essential to driving improvements in population health to address issues related to cost, quality, and outcomes, as well as to promote personalized medicine and precision health. Even though significant progress has been made in harnessing the digitized administrative data, there is still a long way to ensure excellence in precision population health, especially on service utilization and delivery. This Ph.D. dissertation focuses on developing innovative data-driven systems analytics solutions to understand opioid use disorder and its associated harms, and to synthesize today’s evidence to improve tomorrow’s prevention and treatment outcomes on opioid use disorder.Over the past 20 years, the opioid epidemic has been responsible for numerous cases of overdose deaths among Americans and worldwide. The economic burden of the opioid crisis to individuals and society is immense. Furthermore, the opioid overdose epidemic has not impacted communities equally, with increased barriers to care access in an already fragmented system. This thesis comprises five essays that aim to address unanswered questions within the public health and economic literature on opioid use disorder diagnosis and treatment. The first essay of the thesis aims to understand how physicians’ implicit (unconscious) bias contributes to opioid-based treatment disparities in Indiana. The second essay takes a closer look into health care disparities by examining the impact of social determinants on opioid user disorder diagnosis and treatment. The third essay studies how effectively the passage of Indiana Public Law 194 reduced the percentage of doctor shoppers for prescription opioids among Indiana Medicaid enrollees. With the use of network analysis, the fourth essay takes a closer look into the interactions between prescription-opioid doctor-shoppers and providers prescribing opioids under the influence of prescription opioid prescribing guidelines/regulations. Finally, the last essay compares the effect and cost-effectiveness of opioid use disorder treatments based on a self-developed individualized state transition model. These essays collectively provide a data-analytics framework to study population-level opioid use disorder outcomes, investigate the impact of current public approaches on the opioid overdose epidemic, and inform policymakers and the general community about the social and structural determinants affecting communities and populations vulnerable to the epidemic.
Additional file 3 of Association between diastolic blood pressure during the first 24 h and 28-day mortality in patients with septic shock: a retrospective observational study
Creators: name: Gao, Zhiwei
name: Li, Cong
name: Chen, Hui
name: Chen, Dongyu
name: Ma, ShaoLei
name: Xie, Jianfeng
name: Wu, Changde
name: Liu, Ling
name: Yang, Yi
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Science Policy
subject: Computational Biology

description: Additional file 3. Baseline characteristics of the study population according to mDBP24h cutoff value.
title: Eyetracking data during observation of movement primitive generated motion
Creators: name: Knopp, Benjamin
name: Auras, Daniel
name: Schütz, Alexander
name: Endres, Dominik
Publisher: name: TAM DataHub
Year: 0
Subjects: subject: 110-02 Biologische Psychologie und Kognitive Neurowissenschaften

description: # Movement Primitive Gaze Data This archive contains data to recreate the paper "Reading Decisions from Gaze Direction during Graphics Turing Test of Gait Animation". The accompanying code and further information can be obtained here: https://gitlab.uni-marburg.de/knoppbe/movementprimitivegaze ## Files - `eyedata/*.txt`: Files containing eyetracking data, most importantly the point of regard in pixel coordinates of the recorded videos (which are not part of this archive) - `keypoint_labels/*.h5`: Files containing the pixel positions of keypoints (stimulus displaying monitor, avatar body landmarks) - `postcalibration.json`: Contains offsets to post-calibrate gaze data. It is provided here, to enable analysis without videos. Use `src/plot_postcal.py` to reproduce. - `temp_exp1.json`: Contains decision data from 2AFC Experiment (Please see https://gitlab.uni-marburg.de/knoppbe/mp-identification.git on how to produce this file) - `preprocessed_data.json`: Contains preprocessed decision data from 2AFC Experiment (Please see https://gitlab.uni-marburg.de/knoppbe/mp-identification.git on how to produce this file)
description: We investigated gaze direction during movement observation. The eye movement data were collected during an experiment, in which different models of movement production (based on movement primitives, MPs) were compared in a two alternatives forced choice task (2AFC). In each trial, participants observed side-by-side presentation of two naturalistic 3D-rendered human movement videos, where one video was based on motion captured gait sequence, the other one was generated by recombining the machine-learned MPs to approximate the same movement. The participants' task was to discriminate between these movements while their eye movements were recorded. We are complementing previous binary decision data analyses with eye tracking data. Here, we are investigating the role of gaze direction during task execution. We computed how much information is shared between gaze features extracted from eye tracking data and decisions of the participants, and between gaze features and correct answers. We found that eye movements reflect the decision of participants during the 2AFC task, but not the correct answer. This result is important for future experiments (possibly in virtual reality), which should take advantage of eye tracking to complement binary decision data.
Effects of laser power and exposure time on the avian eye: implications for the use of bird deterrents
Creators: name: Harris, Deona L
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Animal physiological ecology

description: Laser deterrents have been used as a method of deterring birds from problem areas such as fisheries, agricultural fields and airports. This method is considered a nonlethal means of control although lasers are known to cause visual lesions and loss of visual acuity in humans and other animals. Birds have a complex visual system which is necessary for behaviors critical to their survival, such as hunting and foraging, and predator vigilance. The purpose of this study is to determine the safety of laser deterrents for avian eyes using two species of birds: house sparrows (Passer domesticus) and European Starlings (Sturnus vulgaris). We found evidence that laser exposure can cause corneal edema, cataracts, retinal atrophy, displacement of the photoreceptor nuclei, and degeneration of the scleral cartilage. The laser exposure time was an important factor in the likelihood of developing corneal edema and retinal atrophy in starlings. Our findings suggest that lasers may not be completely safe for use as bird deterrents, but further research should be done to find possible solutions to improve laser safety from the avian viewpoint.
Sample Size Determination in Multivariate Parameters With Applications to Nonuniform Subsampling in Big Data High Dimensional Linear Regression
Creators: name: Wang, Yu
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Statistics not elsewhere classified

description: Subsampling is an important method in the analysis of Big Data. Subsample size determination (SSSD) plays a crucial part in extracting information from data and in breaking
the challenges resulted from huge data sizes. In this thesis, (1) Sample size determination
(SSD) is investigated in multivariate parameters, and sample size formulas are obtained for
multivariate normal distribution. (2) Sample size formulas are obtained based on concentration inequalities. (3) Improved bounds for McDiarmid’s inequalities are obtained. (4) The
obtained results are applied to nonuniform subsampling in Big Data high dimensional linear
regression. (5) Numerical studies are conducted.
The sample size formula in univariate normal distribution is a melody in elementary
statistics. It appears that its generalization to multivariate normal (or more generally multivariate parameters) hasn’t been caught much attention to the best of our knowledge. In
this thesis, we introduce a definition for SSD, and obtain explicit formulas for multivariate
normal distribution, in gratifying analogy of the sample size formula in univariate normal.
Commonly used concentration inequalities provide exponential rates, and sample sizes
based on these inequalities are often loose. Talagrand (1995) provided the missing factor to
sharpen these inequalities. We obtained the numeric values of the constants in the missing
factor and slightly improved his results. Furthermore, we provided the missing factor in
McDiarmid’s inequality. These improved bounds are used to give shrunken sample sizes
3D And Electromyographic Evaluation Of Upper Extremity Movement Patterns Of Trans-Radial Amputees
Creators: name: Pobatschnig, Barbara
name: Kranzl, Andreas
Publisher: name: Zenodo
Year: 2017

description: Assessment tests are the gold standard to measure the functionality of hand prostheses, but they evaluate how fast a patient is able to perform a specific task and do not assess quality of movement. The wide range of UL movements leads to a big challenge to assess and interpret data. Therefore, UL 3D motion analysis is a difficult task in clinical practice, thus there is still a major lack of published normative data. Further research is needed to understand the effectiveness of medical treatments.
Additional file 1 of A national population-based study of cannabis use and correlates among U.S. veterans prescribed opioids in primary care
Creators: name: Zaman, Tauheed
name: Bravata, Dawn M.
name: Byers, Amy L.
name: Krebs, Erin E.
name: Leonard, Samuel J.
name: Sandbrink, Friedhelm
name: Barker, Wylie
name: Keyhani, Salomeh
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Neuroscience
Pharmacology
Biotechnology
Cancer
Mental Health

description: Additional file 1.
Predictive Quality Analytics
Creators: name: Semssar, Salim A
Publisher: name: Purdue University Graduate School
Year: 2022
Subjects: Process control and simulation
Manufacturing management
Manufacturing safety and quality
Other engineering not elsewhere classified
Engineering practice
Manufacturing processes and technologies (excl. textiles)

description: Quality drives customer satisfaction, improved business performance, and safer products. Reducing waste and variation is critical to the financial success of organizations. Today, it is common to see Lean and Six Sigma used as the two main strategies in improving Quality. As advancements in information technologies enable the use of big data, defect reduction and continuous improvement philosophies will benefit and even prosper. Predictive Quality Analytics (PQA) is a framework where risk assessment and Machine Learning technology can help detect anomalies in the entire ecosystem, and not just in the manufacturing facility. PQA serves as an early warning system that directs resources to where help and mitigation actions are most needed. In a world where limited resources are the norm, focused actions on the significant few defect drivers can be the difference between success and failure
CHARACTERIZATION AND ASSESSMENT OF LUNG AND BONE MARROW DERIVED ENDOTHELIAL CELLS AND THEIR BONE REGENERATIVE POTENTIAL
Creators: name: Valuch, Conner Riley
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Biochemistry and cell biology not elsewhere classified

description: Fracture repair is costly and difficult to treat. One of the main causations of nonunion is a lack of essential blood supply. The needed blood is supplied by the growth of new blood vessels, a process known as angiogenesis, that invade the damaged tissue early in the healing process. We proposed using bone tissue engineering as an effective therapy. This therapy uses stem cells to aid in tissue regeneration. Endothelial progenitor cells (EPCs) were selected due to their ability to form tube-like networks in vitro. EPCs were isolated from murine bone marrow and lung tissue. We tested EPC’s tube forming, proliferative, and wound migration ability in vitro. To test their ability in vivo we created a femoral fracture in young and old mice. EPCs were seeded to the fracture site upon a collagen scaffold. The in vitro studies displayed that the bone marrow and lung-derived endothelial cells presented EPC traits. In the mouse fracture model bone marrow, endothelial cells did not significantly improve the healing process. In the future, we want to improve our cell extraction and purification method, as well as test a new stem cell delivery biomaterial. We also want to select and use a growth factor (GF) that can help to promote bone regeneration in tandem with the EPCs.
Additional file 1 of Binge drinking associated with mean temperature: a cross-sectional study among Mexican adults living in cities
Creators: name: Carnalla, Martha
name: López-Olmedo, Nancy
name: Ramírez-Toscano, Yenisei
name: Cárdenas-Cárdenas, Luz Mery
name: Canto-Osorio, Francisco
name: Rengifo-Reina, Herney
name: Barrera-Núñez, David
name: Quiroz-Reyes, Josúe Alai
name: Colchero, M. Arantxa
name: Barrientos-Gutiérrez, Tonatiuh
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Table A.1. Characteristics of current drinkers in the last year
SPANISH EXILED LITERATURE IN THE JEWISH COMMUNITY OF AMSTERDAM
Creators: name: Rodriguez, Hernan Javier J Matzkevich
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Literature in Spanish and Portuguese
Jewish studies
Studies in religious traditions (excl. Eastern, Jewish, Christian and Islamic traditions)

description: My dissertation analyzes the hyphenated Judeo-Spanish cultural identity that Amsterdam’s Jewish community developed during the seventeenth century and how the works its members authored reflected such identity. Yosef Kaplan, who coined the critical concept of “New Jew,” a term that refers to the Jewish community of Amsterdam, provides the theoretical framework for this research. Raised as Catholics in Spain, this community was without contact with any organized Jewish community. Therefore, the so-called “New Jews” built their Jewish identity in Amsterdam while still carrying the memory of Spain’s experiences. Chapter 2 focuses on the relationship between Amsterdam Jewish authors’ physical and cultural journey and the history of Iberian Jews from the end of the fifteenth century in Spain through their settlement in Amsterdam in the seventeenth century. Chapter 3 exemplifies this cultural phenomenon in the poet Miguel (Daniel Levi), de Barrios, discussing how his poetry mutated—as the author himself did—from Christianity to Judaism. Chapter 4 addresses the study of anti-Jewish Iberian works composed by authors such as Vicente da Costa Matos, Francisco de Quevedo, and Francisco de Torrejoncillo. This chapter provides the anti-Jewish Iberian background that explains the contestation against Catholicism that Jewish authors later developed in Amsterdam. Chapter 5 defends the existence of a differentiated anti-Catholic polemic genre germane to seventeenth-century Amsterdam’s Jewish community and other communities composed of Jewish-Spanish exiles. This a comparative analysis of works by Daniel de Barrios, Abraham Gómez Silveira, Isaac Cardoso, Saul Levi Mortera, Orobio de Castro, Antonio Enríquez Gómez, Abraham Pereyra, and several anonymous works. Chapter 6 analyses Menasseh ben Israel’s Esperanza de Israel as a work that vindicates the concept of Jewish hope within the framework of the exploratory travels and the epistemological changes that defined the Early Modern period. Altogether, by focusing on the literature developed by Judeo-Spanish writers, my dissertation enhances the comprehension of the hyphenated cultural identity developed by Jewish communities composed of exiles from the Iberian Peninsula. These people held a divided identity that they tried to conciliate in their works, which unified the Hispanic cultural background and the Judaism they recovered once they left Portugal and Spain.
Additional file 2 of Binge drinking associated with mean temperature: a cross-sectional study among Mexican adults living in cities
Creators: name: Carnalla, Martha
name: López-Olmedo, Nancy
name: Ramírez-Toscano, Yenisei
name: Cárdenas-Cárdenas, Luz Mery
name: Canto-Osorio, Francisco
name: Rengifo-Reina, Herney
name: Barrera-Núñez, David
name: Quiroz-Reyes, Josúe Alai
name: Colchero, M. Arantxa
name: Barrientos-Gutiérrez, Tonatiuh
Publisher: name: figshare
Year: 2024
Subjects: Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Cancer
Science Policy

description: Table A.2. Characteristics of individuals excluded due to missing information on temperature and individual included in the analysis.
Prediction of Infrasound Emission from Horizontal Axis Wind Turbines
Creators: name: He, Dazhuang
Publisher: name: Purdue University Graduate School
Year: 2021
Subjects: Acoustics and noise control (excl. architectural acoustics)
Aerodynamics (excl. hypersonic aerodynamics)

description: Wind energy is one of the fastest-growing renewable energy technologies, and horizontal axis wind turbines (HAWT) have been the most common device to convert wind kinetic energy into electrical energy. As the capacities of wind turbines and scales of wind farm constructions are rapidly increasing over time, environmental impacts of wind energy are becoming more relevant and raising more attention than ever before. One of the major environmental concerns is noise emission from wind energy facilities, especially low-frequency noise and infrasound that allegedly cause so-called wind turbine syndrome. Therefore, a numerical simulation program capable to predict low-frequency noise and infrasound emission from wind turbines is a useful tool to aid future wind energy development. In this study of this thesis, a computer program named TDRIP (Time Domain Rotor Infrasound Prediction) is developed based on acoustic analogy theories. Farassat’s formulation 1A, a solution to Ffowcs Williams-Hawkings (FW-H) equation, is implemented in the TDRIP program to compute aerodynamically generated sound. The advantage of this program is its capability to simultaneously compute infrasound emission of multiple wind turbines in time domain, which is a challenging task for other aerodynamic noise prediction methods. The developed program is validated against results obtained from computational fluid dynamics (CFD) simulations. The program is then used to compute aerodynamic noise emitted from wind turbine rotors. The effects of wind direction, wind turbine siting, and phase of wind turbine rotation on consequent aerodynamic noise are investigated. Results of aerodynamic noise computation imply that wind turbine siting configuration or wind turbine phase adjustment can help reducing noise level at certain locations, which make the program ideal to be integrated into wind farm siting or control tools.