cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Indurated erythema of abdominal skin: An unusual presentation of metastatic endometrial carcinoma—Case report with literature review
Creators: name: Niebel, Dennis
name: Kranert, Paula
name: Berneburg, Mark
name: Drexler, Konstantin
name: Eichborn, Maria Isabel
name: Braess, Jan
name: Allgäuer, Michael
name: Karrer, Sigrid
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: 610 Medizin

description: Carcinoma erysipelatoides (CE) is a rare clinical manifestation of cutaneous metastasis, which mimics inflammatory conditions such as erysipelas. Depending on the site of the originating tumour, unusual manifestations involving different sites of the body may occur. We herein report a case of a 60-year-old female patient with metastatic endometrial carcinoma presenting as CE of the abdominal skin and the inguinal folds. Even though the diagnosis of advanced malignancy had been established before and she was currently receiving chemotherapy (carboplatin and paclitaxel), the clinical appearance closely resembled fungal (candidal intertrigo) and consecutively bacterial (erysipelas) infection, which resulted in treatment with antimycotics and antibiotics at first. Dermatohistopathological examination of skin biopsies revealed a diffuse and nodular infiltrate of pleomorphic atypical tumour cells with strong expression of cytokeratin 7 and PAX8, also detectable within lymphatic vessels. Therapy comprised antiseptic ointments to prevent superinfection, palliative electron beam radiation and supportive care. Since there were no targetable KRAS-, NRAS- and BRAF-gene mutations, systemic therapy was switched to checkpoint inhibition (pembrolizumab) in combination with lenvatinib. The overall prognosis of cutaneous metastasis of endometrial carcinoma is dismal with most patients succumbing to disease within few months. Similarly, our patient died after 3 months due to sepsis in the course of malignant pleural effusion. We aim to highlight the possibility of unusual sites of CE and the risk of respective clinical misdiagnoses.
Additional file 1: of Effects of whole-body vibration on proxies of muscle strength in old adults: a systematic review and meta-analysis on the role of physical capacity level
Creators: name: Rogan, Slavko
name: Eling De Bruin
name: Radlinger, Lorenz
name: Joehr, Christine
name: Wyss, Christa
name: Neil-Jerome Stuck
name: Bruelhart, Yvonne
name: Bie, Rob De
name: Hilfiker, Roger
Publisher: name: Figshare
Year: 2015
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy

description: Search terms in PubMed. (DOCX 62 kb)
Unpaired Optical Coherence Tomography Angiography Image Super-Resolution via Frequency-Aware Inverse-Consistency GAN
Creators: name: Zhang, Weiwen
name: Yang, Dawei
name: Che, Haoxuan
name: Ran, An Ran
name: Cheung, Carol Y.
name: Chen, Hao
Publisher: name: arXiv
Year: 2023
Subjects: subject: Image and Video Processing (eess.IV)
subject: Computer Vision and Pattern Recognition (cs.CV)
subject: FOS: Electrical engineering, electronic engineering, information engineering
subject: FOS: Computer and information sciences

description: For optical coherence tomography angiography (OCTA) images, a limited scanning rate leads to a trade-off between field-of-view (FOV) and imaging resolution. Although larger FOV images may reveal more parafoveal vascular lesions, their application is greatly hampered due to lower resolution. To increase the resolution, previous works only achieved satisfactory performance by using paired data for training, but real-world applications are limited by the challenge of collecting large-scale paired images. Thus, an unpaired approach is highly demanded. Generative Adversarial Network (GAN) has been commonly used in the unpaired setting, but it may struggle to accurately preserve fine-grained capillary details, which are critical biomarkers for OCTA. In this paper, our approach aspires to preserve these details by leveraging the frequency information, which represents details as high-frequencies ($\textbf{hf}$) and coarse-grained backgrounds as low-frequencies ($\textbf{lf}$). In general, we propose a GAN-based unpaired super-resolution method for OCTA images and exceptionally emphasize $\textbf{hf}$ fine capillaries through a dual-path generator. To facilitate a precise spectrum of the reconstructed image, we also propose a frequency-aware adversarial loss for the discriminator and introduce a frequency-aware focal consistency loss for end-to-end optimization. Experiments show that our method outperforms other state-of-the-art unpaired methods both quantitatively and visually.
description: 11 pages, 10 figures, in IEEE J-BHI, 2024
Lecithocera dirupta Meyrick 1923
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera dirupta

description: 57. Lecithocera dirupta Meyrick, 1923 c: 39
Type locality: India, Tamil Nadu, Palnis
Distribution: Indian records: Tamil Nadu.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 2: Figure S1. of NanoCAGE-XL and CapFilter: an approach to genome wide identification of high confidence transcription start sites
Creators: name: Cumbie, Jason
name: Ivanchenko, Maria
name: Megraw, Molly
Publisher: name: Figshare
Year: 2015
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Genetics
subject: Molecular Biology
subject: 69999 Biological Sciences not elsewhere classified

description: Effect of rRNA depletion on nanoCAGE librariy profile. Panel a: Library constructed with total RNA as template. Panel b: Library constructed with Ribo-Zero depleted RNA as template. Figure S2: Examples of nanoCAGE TSS peak distribution before and after Gâ  -filtering for experiments 2 and 3. Figure S3: Examples of CAGE TSS peak distributions before and after Gâ  -filtering.
Additional file 4: of Womenâ  s birth place preferences in the United Kingdom: a systematic review and narrative synthesis of the quantitative literature
Creators: name: Hollowell, Jennifer
name: Yangmei Li
name: Malouf, Reem
name: Buchanan, James
Publisher: name: Figshare
Year: 2016
Subjects: subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Quality appraisal of stated preference studies. Describes the findings of the critical appraisal of the five included stated preference studies using an ISPOR checklist. (DOCX 71Â kb)
Lecithocera dubitans Meyrick 1926
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera dubitans

description: 58. Lecithocera dubitans Meyrick, 1926: 157
Type locality: Malaysia, Mt. Murud, 6300ft
Distribution: Indian records: Maharashtra. Global records: Malaysia.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Lecithocera elephantopa Brachmia
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera elephantopa

description: 59. Lecithocera elephantopa (Meyrick, 1910c: 222) (Brachmia)
Type locality: India, North Bengal, Bhogaon, Purneah district. Konkan, Bombay. Karnataka, Coorg. Tamil Nadu, Nilgiris
Distribution: Indian records: Karnataka, Maharashtra, Tamil Nadu, West Bengal.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 1: of Importins promote high-frequency NF-κB oscillations increasing information channel capacity
Creators: name: Korwek, Zbigniew
name: Tudelska, Karolina
name: Paweł Nałęcz-Jawecki
name: Czerkies, Maciej
name: Prus, Wiktor
name: Markiewicz, Joanna
name: Kochańczyk, Marek
name: Lipniacki, Tomasz
Publisher: name: Figshare
Year: 2016
Subjects: subject: Molecular Biology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences

description: Computational model description. (PDF 349 kb)
Additional file 4: of Importins promote high-frequency NF-κB oscillations increasing information channel capacity
Creators: name: Korwek, Zbigniew
name: Tudelska, Karolina
name: Paweł Nałęcz-Jawecki
name: Czerkies, Maciej
name: Prus, Wiktor
name: Markiewicz, Joanna
name: Kochańczyk, Marek
name: Lipniacki, Tomasz
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Full confocal images with marked cells used for fluorescence quantification after 10 ng/ml TNFα stimulation for 0, 15, 30, 60, 90 and 180 min. Data table show raw nuclear to total NF-κB ratio and normalized total IκBα to total NF-κB ratio for each analysed cell (for quantification details see Methods). (PDF 1380 kb)
Additional file 1: of Acute and preventive management of anaphylaxis in German primary school and kindergarten children
Creators: name: Kilger, Magdalena
name: Range, Ursula
name: Vogelberg, Christian
Publisher: name: Figshare
Year: 2015
Subjects: subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Excerpt of the questionnaire for teachers/child-care providers about anaphylactic reactions in children (questions not shown concerned demographic background). (DOCX 21Â kb)
Ideal treatment timing of orthodontic anomalies—a German clinical S3 practice guideline
Creators: name: Kirschneck, Christian
name: Proff, Peter
name: Lux, Christopher
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: ; Malocclusion; Interceptive therapy; Dysgnathia; Dentition; Orofacial dyskinesia
subject: 610 Medizin

description: Purpose Ideal treatment timing in orthodontics is controversially discussed depending on the type and extent of the dysgnathia and malocclusion present, especially with regard to efficiency, patient burden and treatment efforts of early compared to regular or late treatment. This German clinical practice guideline aims to clarify, at which time points an orthodontic anomaly can be effectively treated and how treatment efficiency differs depending on treatment timing. Methods A systematic literature search was performed in various guideline databases and databases PROSPERO, MEDLINE (PubMed), Cochrane Library, Web of Science, ClinicalTrials.gov and the International Clinical Trials Registry Platform according to a predefined PICO (Population, Intervention, Comparison and Outcomes with added qualitative search terms) search algorithm and strategy. Appraisal of scientific evidence of the individual studies checked for eligibility was carried out according to SIGN (Scottish Intercollegiate Guidelines Network), AMSTAR II (Assessing the Methodological Quality of Systemic Reviews), and AXIS (Appraisal Tool to Assess the Quality of Cross-sectional Studies) tools. Only controlled studies with a high, acceptable or moderate quality (and thus an acceptable risk of bias) were considered. Results A total of 309 studies of over 11,000 sources screened were identified to be eligible for inclusion and critically appraised for study quality and risk-of-bias. No relevant guidelines relating to the aims of the present guideline were found. Elected delegates of in total 21 German scientific societies and organizations agreed upon a total of 19 evidence-based statements and recommendations based on a nominal consensus process. Conclusions Although most malocclusions can be effectively treated both in the early, late mixed, and permanent dentition, evidence suggests that therapy of a pronounced skeletal or dental class II anomaly can be started early to reduce the risk of dental anterior tooth trauma, whereas in a moderate class II anomaly, therapy can preferably be carried out before or during the pubertal growth peak. Therapy of a skeletal or dental class III anomaly should be started early, as this also reduces the need for later surgery to correct the anomaly. The treatment of a pronounced skeletal or dental transverse anomaly should be started early in the upper jaw in order to utilize the high adaptivity of the maxillary structures in young patients.
Lecithocera eludens Meyrick 1918
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera eludens

description: 60. Lecithocera eludens Meyrick, 1918b: 108
Type locality: India, Tamil Nadu, Nilgiris
Distribution: Indian records: Tamil Nadu.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 2: of Acute and preventive management of anaphylaxis in German primary school and kindergarten children
Creators: name: Kilger, Magdalena
name: Range, Ursula
name: Vogelberg, Christian
Publisher: name: Figshare
Year: 2015
Subjects: subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: List of items that were included in questionnaire for parents about anaphylactic reactions in children. (DOCX 26Â kb)
MOESM1 of Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma
Creators: name: Bussey, Kimberly
name: Bapat, Aditi
name: Linnehan, Claire
name: Wandoloski, Melissa
name: Dastrup, Erica
name: Rogers, Erik
name: Gonzales, Paul
name: Demeure, Michael
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1. Supplemental Methods and Results for studies of TP53 mutation, p53 codon 72 ploymorphism, and MDM2 SNP309 polymorphism in ACC tumors, Supplemental Tables 1â  5 and Supplemental Figures 1â  5.
Additional file 3: of Importins promote high-frequency NF-κB oscillations increasing information channel capacity
Creators: name: Korwek, Zbigniew
name: Tudelska, Karolina
name: Paweł Nałęcz-Jawecki
name: Czerkies, Maciej
name: Prus, Wiktor
name: Markiewicz, Joanna
name: Kochańczyk, Marek
name: Lipniacki, Tomasz
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: Biotechnology
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Figure S1. Analysis of functional TNFα degradation in experimental conditions. (a) Immunostaining confocal images of unstimulated cells and cells stimulated for 15 and 30 min with fresh TNFα at 10 ng/ml concentration. (b) Immunostaining images of cells stimulated for 15 and 30 min with the media harvested from above cells stimulated for 6 h with TNFα, at the initial concentration of 10 ng/ml. (c,d) Simulated single cell (thin lines) and population average (bold lines) trajectories in responses to TNFα stimulation with concentration D 1 = 10 ng/ml (orange lines) and D 2 = 1.15 ng/ml (blue lines). At the assumed TNFα degradation coefficient cdeg = 10-4/s the initial TNFα concentration D 1 is reduced to D 2 after 6 h. Figure S2. Model simulation trajectories showing unstimulated, equilibrated cells. Figure S3. Model simulation trajectories for A20-deficient cells in response to 10 ng/ml TNFα stimulation, studied experimentally by Lee et al. [12]. As in experiment, A20-deficient cells respond by a stable NF-κB translocation. Figure S4. Model simulated responses to single 10 ng/ml TNFα pulses of various durations. Simulations correspond to experimental data [30, 64] showing single NF-κB pulses of amplitude almost independent of pulse duration. Figure S5. Model simulated responses to the series of three 5 min, 10 ng/ml TNFα pulses, with pulse repeat of 60 min, 100 min, 200 min; corresponding to the experiment by Ashall et al. [34], who observed that almost all cells respond to first pulse, while about 30 % fraction of cells respond to the second and third pulse for 60 min, 100 min repeats. For 200 min repeats almost all cells respond to three TNFα pulses. Figure S6. Model simulated responses to repeated 10 ng/ml TNFα pulses corresponding to the experiment by Zambrano et al. [40], who observed NF-κB oscillations in response to pulses repeated every 45 min. Figure S7. Scatter plots showing evolution of the total IκBα/total NF-κB ratio and nuclear NF-κB/total NF-κB ratio in response to 1 μg/ml LPS. The scatter plot is based on quantified confocal images shown in Additional file 5. (PDF 3475 kb)
Unusually swift response of relapsed Burkitt leukemia to R‐DHAP
Creators: name: Harrer, Dennis Christoph
name: Denk, Alexander
name: Keil, Felix
name: Menhart, Karin
name: Mayer, Stephanie
name: Wolff, Daniel
name: Edinger, Matthias
name: Herr, Wolfgang
name: Grube, Matthias
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: allogeneic stem cell transplantation, Burkit leukemia, R-DHAP, relapse, salvage therapy
subject: 610 Medizin

description: Burkitt leukemia (BL) represents a highly aggressive lymphoma characterized by proliferation rates of around 100%, and a frequent spread into the central nervous system. If standard frontline chemotherapy fails, the prognosis is usually dismal, and reports on successful effective salvage therapy strategies for patients with relapsed/refractory BL are scant. Here, we report on a 40-year-old female patient who suffered an early relapse of BL three months after the completion of frontline chemoimmunotherapy. Strikingly, after only one cycle of R-DHAP chemotherapy, the patient showed CR of BL enabling swift transition to a consolidating allogeneic stem cell transplantation. A 40-year-old previously healthy woman presented to the hospital with fatigue and incessant epistaxis, and a diagnosis of BL was made upon histological examination of a bone marrow biopsy. Treatment was initiated according to the GMALL 2002 B-NHL/ALL protocol, which could induce complete molecular remission. Nevertheless, three months after chemotherapy, the patient exhibited BL relapse in the bone marrow, and on Fluorodeoxyglucose (FDG)–PET-imaging. The relapse therapy was started with R-DHAP, and after only one cycle, the patient once again entered complete remission (CR) paving the way for allogeneic stem cell transplantation. Unfortunately, the patient again relapsed five months after transplantation prompting salvage therapy with R-DHAC and the execution of the second stem cell transplantation. However, one month after the second transplantation the patient presented with chemorefractory meningeosis leukemia resulting in the initiation of palliative care treatment. In summary, we report on rapid CR of relapsed BL after a single cycle of rituximab-DHAP. Given a paucity of clinical trials on the treatment of patients with r/r BL, we intend to highlight the potential efficacy of rituximab-DHAP as salvage therapy in those patients.
Additional file 5: of Importins promote high-frequency NF-κB oscillations increasing information channel capacity
Creators: name: Korwek, Zbigniew
name: Tudelska, Karolina
name: Paweł Nałęcz-Jawecki
name: Czerkies, Maciej
name: Prus, Wiktor
name: Markiewicz, Joanna
name: Kochańczyk, Marek
name: Lipniacki, Tomasz
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology

description: Full confocal images with marked cells used for fluorescence quantification after 1 μg/ml LPS stimulation. Data table show raw nuclear to total NF-κB ratio and normalized total IκBα to total NF-κB ratio for each analysed cell (for quantification details see Methods). (PDF 1238 kb)
Additional file 7: of Importins promote high-frequency NF-κB oscillations increasing information channel capacity
Creators: name: Korwek, Zbigniew
name: Tudelska, Karolina
name: Paweł Nałęcz-Jawecki
name: Czerkies, Maciej
name: Prus, Wiktor
name: Markiewicz, Joanna
name: Kochańczyk, Marek
name: Lipniacki, Tomasz
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology

description: Full confocal images of cells stimulated with 10 ng/ml TNFα for 0, 5, 10, 15, 20, and 30 min. (PDF 733 kb)
Lecithocera gozmanyi Pathania & Rose 2004
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera gozmanyi

description: 61. Lecithocera gozmanyi Pathania & Rose, 2004b: 228
Type locality: India, Uttarakhand, Dehra Dun
Distribution: Indian records: Punjab, Uttarakhand.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Association of polymorphous light eruption with NOD ‐2 and TLR ‐5 gene polymorphisms
Creators: name: Kurz, B.
name: Arndt, S.
name: Unger, P.
name: Ivanova, I.
name: Berneburg, Mark
name: Hellerbrand, C.
name: Karrer, Sigrid
Publisher: name: Universität Regensburg
Year: 2022
Subjects: subject: GRAFT-VERSUS-HOST; LANGERHANS CELL-MIGRATION; STOP CODON POLYMORPHISM; CROHNS-DISEASE; TRANSPLANTATION; NOD2/CARD15; PREVALENCE; EXPRESSION; RADIATION; VARIANTS;
subject: 610 Medizin

description: Background Polymorphous light eruption (PLE) is a common, immunologically mediated, photosensitive skin disease. After ultraviolet-B (UV-B) irradiation, patients with PLE show reduced Langerhans cell (LC) depletion in the epidermis, which results in a non-suppressive microenvironment in the skin. Interestingly, severe acute graft-versus-host disease (aGvHD) occurred in stem cell transplanted patients that showed no or incomplete depletion of LCs after UVB irradiation. Genetic variation in nucleotide-binding oligomerization domain 2 (NOD-2) and toll-like receptor 5 (TLR-5) genes also confers susceptibility to aGvHD. Objectives We hypothesized that PLE is associated with genetic variation in the NOD-2 and TLR-5 genes. Methods We investigated single-nucleotid polymorphisms (SNPs) of NOD-2 (R702W, G908R, 3020Cins) and TLR-5 (A592S, P616L, N392STOP) in skin biopsies of patients with PLE (n = 143) and in healthy controls (n = 104) using restriction fragment length polymorphism analysis. Results The frequency of NOD-2 alleles with the SNP R702W was significantly higher in PLE than in controls (31.8% vs. 6.3%; P < 0.0001), and homozygous carriers of this mutation were more common in PLE (27.9% vs. 0%; P < 0.0001). For SNP 3020Cins, the allele frequency (7.3% vs. 0.7%; P = 0.0025) and the number of heterozygotes (14.7% vs. 1.3%; P = 0.0019) were higher in PLE. The frequency of alleles with the N392STOP SNP of the TLR5 gene, which is associated with a truncated, non-functional receptor, was significantly higher in PLE (21% vs. 5%; 7% vs. 1% homozygotes, 28% vs. 8% heterozygotes; P < 0.0001). The other SNPs did not differ significantly. Conclusions This study yielded a high frequency of functional SNPs in the NOD-2 and TLR-5 genes in PLE. The same SNPs are associated with aGvHD and there are similarities in the reaction of LCs after UVB irradiation between aGvHD and PLE. This leads to the hypothesis that patients with PLE may be more susceptible to developing GvHD after stem cell transplantation, an assumption that needs to be investigated further.
Lecithocera hypsipola Meyrick 1926
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera hypsipola

description: 62. Lecithocera hypsipola Meyrick, 1926 c: 290
Type locality: India, Uttarakhand, Kumaon
Distribution: Indian records: Uttarakhand.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 16: of Deep landscape update of dispersed and tandem repeats in the genome model of the red jungle fowl, Gallus gallus, using a series of de novo investigating tools
Creators: name: Guizard, Sébastien
name: Piégu, Benoît
name: Arensburger, Peter
name: Guillou, Florian
name: Bigot, Yves
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Marine Biology

description: Histograms showing the densities of TEs and TE hot spots in galGal4 chromosomes for the 8 sub-families of CR1 elements. Histograms of TE model density and TE hot spot density were calculated for all galGal4 chromosomes, except chromosome 32 (too small; 1028 bp). (PDF 532 kb)
Additional file 2: of Quality of care for remote orthopaedic consultations using telemedicine: a randomised controlled trial
Creators: name: Buvik, Astrid
name: Bugge, Einar
name: Knutsen, Gunnar
name: SmĂĽbrekke, Arvid
name: Wilsgaard, Tom
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Cell Biology
subject: Neuroscience
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: Computational Biology

description: Questionnaire for RMS allocated patients, English translation. English translation of questionnaire for patients allocated to telemedicine consultation, immediately after the consultation. (DOCX 30 kb)
Lecithocera ianthodes Meyrick 1931
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera ianthodes

description: 63. Lecithocera ianthodes Meyrick, 1931d: 80
Type locality: India, Uttarakhand, Dehra Dun
Distribution: Indian records: Himachal Pradesh, Uttarakhand.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 9: Figure S8. of The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2
Creators: name: Hendus-Altenburger, Ruth
name: Pedraz-Cuesta, Elena
name: Olesen, Christina
name: Papaleo, Elena
name: Schnell, Jeff
name: Hopper, Jonathan
name: Robinson, Carol
name: Pedersen, Stine
name: Kragelund, Birthe
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Sociology
subject: FOS: Sociology
subject: Developmental Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Purity of protein preparations. (a) Coomassie-stained SDS-PAGE (Bio-Rad) of hNHE1cdt WT, variants, and iaERK2. A low molecular weight marker (LMW) was used as standard (GE Healthcare). (b) Phosphorylation of the hNHE1cdt variants by aERK2 leads to an upward shift on SDS-PAGE towards apparent higher molecular weight relative to the unphosphorylated state. (PDF 1194 kb)
Lecithocera ichorodes Meyrick 1910
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera ichorodes

description: 64. Lecithocera ichorodes Meyrick, 1910b: 445
Type locality: India, Tamil Nadu, Nilgiris
Distribution: Indian records: Tamil Nadu.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Metatrichia
Creators: name: Winterton, Shaun L.
name: Woodley, Norman E.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Scenopinidae
Metatrichia

description: Key to extant species of Metatrichia from the Australasian region
1. Body without white, scale-like setae (female only) (Papua New Guinea) ..................................... M. papuana Kelsey
- Body with numerous white, scale-like setae on head thorax and abdomen ................................................................. 2
2. Male abdominal tergites 5–7 with cream-white markings; postalar callus and sclerites around wing base with tan- brown markings (eastern Australia)................................................................................ M. waterhousei (Paramonov)
- Male abdominal tergites 6–7 with faint markings; postalar callus and sclerites around wing base uniformly dark (male only) (northern Australia) ................................................................................................. M. dhimurru sp. nov.
description: Published as part of Winterton, Shaun L. & Woodley, Norman E., 2009, New species of Metatrichia Coquillett (Diptera: Scenopinidae) from Australia and Venezuela, pp. 42-51 in Zootaxa 2094 on pages 44-45, DOI: 10.5281/zenodo.187576
TARGETING GEN Z CONSUMERS EFFECTIVELY
Creators: name: Mukhlisa Ergasheva - author, Student of Millat Umidi University; Business Management faculty (Pearson BTEC).
Publisher: name: Zenodo
Year: 2024

description: One of the most digitally connected, socially conscious and diverse consumer groups are Generation Z, individuals born between 1995 and 2012. Their unique preferences and values are resulting in changing the marketing landscape, as they are entering the workforce. The difference with previous generations reflects in prioritizing inclusivity, authenticity, personal and social values. Brands in Uzbekistan may have challenges in meeting expectations of digital natives and applying local cultural nuances. The aim of this article is to investigate effective marketing strategies for targeting Generation Z, by surveying their digital engagement behavior and value-driven brand preferences. As market is becoming dominated by Gen Z, I found this area needed to be explored in Uzbekistan.
Additional file 3: of Quality of care for remote orthopaedic consultations using telemedicine: a randomised controlled trial
Creators: name: Buvik, Astrid
name: Bugge, Einar
name: Knutsen, Gunnar
name: SmĂĽbrekke, Arvid
name: Wilsgaard, Tom
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Medicine
subject: Neuroscience
subject: Developmental Biology
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Questionnaire for the orthopaedic surgeon performing the consultation, English translation. English translation of questionnaire for the orthopaedic surgeon performing the consultation, immediately after the consultation. (DOCX 16 kb)
Additional file 3: Figure S3. of The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2
Creators: name: Hendus-Altenburger, Ruth
name: Pedraz-Cuesta, Elena
name: Olesen, Christina
name: Papaleo, Elena
name: Schnell, Jeff
name: Hopper, Jonathan
name: Robinson, Carol
name: Pedersen, Stine
name: Kragelund, Birthe
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Developmental Biology
subject: Hematology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Analysis of the hNHE1cdt-iaERK2 complex by size exclusion chromatography and circular dichroism (CD). (a) Size exclusion chromatography profiles of the hNHE1cdt WT (blue), iaERK2 (black), and a mixture of both (red). Subtraction of the individual runs from the mixture identifies a broad underlying peak with elution properties of the complex (grey). (b) Zoom from panel (a). Fractions taken for SDS-PAGE analysis (see panel (c)) are indicated by grey bars. (c) Coomassie-stained SDS-PAGE of fractions from individual runs, as indicated in panel (b). (d) Mean residual ellipticity CD spectra of hNHE1cdt WT, iaERK2, and mixture reveal no significant gain of secondary structure upon complex formation. (PDF 5632 kb)
Additional file 1: Figure S1. of Founder events and pre-glacial divergences shape the genetic structure of European Collembola species
Creators: name: Saltzwedel, Helge Von
name: Scheu, Stefan
name: Schaefer, Ina
Publisher: name: Figshare
Year: 2016
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Plant Biology

description: Map of all sampling points and approcimate sketches of extent of permanent ice shields (white filled areas) and borders of polar desert (red, dotted line) and permafrost (black, dashed line) climate during the Last Glacial Maximum (~20,000 years ago) that strongly shaped genetic and species richness above the ground in central and northern Europe (after Hewitt [69]). Figure S2. Haplotype Networks of Ceratophysella denticulata. Figure S3. Haplotype Networks of Folsomia quadrioculata. Figure S4. Haplotype Networks of Isotomiella minor. Figure S5. Bayesian phylogeny based on COI. Figure S6. Bayesian phylogeny based on H3. Figure S7. Molecular divergence estimates of dataset (2). Figure S8. Molecular phylogeny and divergence estimates of 28 species of Collembola based on COI calculated with BEAST. Figure S9. Molecular divergence estimates in C. denticulata of a) dataset (1) and b) dataset (3). Outgroups: C. = Ceratophysella, H. = Hypogastrura, X = Xenylla, G = Gomphiocephalus. Figure S10. Molecular divergence estimates in F. quadrioculata of a) dataset (1) and b) dataset (3). Outgroups: F. = Folsomia, I. = Isotoma, C. = Cryptopygus, A. = Anurophorus. Figure S11. Molecular divergence estimates in I. minor of a) dataset (1) and b) dataset (3). Outgroups: F. = Folsomia, I. = Isotoma, C. = Cryptopygus, A. = Anurophorus. (PDF 920 kb)
Lecithocera immobilis Meyrick 1918
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera immobilis

description: 65. Lecithocera immobilis Meyrick, 1918b: 103
Type locality: India, Tamil Nadu, Coimbatore
Distribution: Indian records: Himachal Pradesh, Jammu and Kashmir, Punjab, Tamil Nadu, Uttarakhand.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on page 66, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 1 of systemPipeR: NGS workflow and report generation environment
Creators: name: Backman, Tyler
name: Girke, Thomas
Publisher: name: Figshare
Year: 2016
Subjects: subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: RNA-Seq Workflow Example. Case study to illustrate the utilities of systemPipeR using an RNA-Seq workflow as example. (PDF 89 kb)
Additional file 7: Table S4. of Effectiveness of multifaceted implementation strategies for the implementation of back and neck pain guidelines in health care: a systematic review
Creators: name: Suman, Arnela
name: Dikkers, Marije
name: Schaafsma, Frederieke
name: Tulder, Maurits Van
name: Anema, Johannes
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Interventions of included studies according to EPOC taxonomy (all on professional level unless stated otherwise). (DOCX 15 kb)
Comparing numerical methods for hydrodynamics in a one-dimensional lattice spin model
Creators: name: Yi-Thomas, Stuart
name: Ware, Brayden
name: Sau, Jay D.
name: White, Christopher David
Publisher: name: arXiv
Year: 2023
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Gases (cond-mat.quant-gas)
subject: FOS: Physical sciences

description: In ergodic quantum spin chains, locally conserved quantities such as energy or particle number generically evolve according to hydrodynamic equations as they relax to equilibrium. We investigate the complexity of simulating hydrodynamics at infinite temperature with multiple methods: time evolving block decimation (TEBD), TEBD with density matrix truncation (DMT), the recursion method with a universal operator growth hypothesis (R-UOG), and operator-size truncated (OST) dynamics. Density matrix truncation and the OST dynamics give consistent dynamical correlations to $t=60/J$ and diffusion coefficients agreeing within 1%. TEBD only converges for $t\lesssim 20$, but still produces diffusion coefficients accurate within 1%. The universal operator growth hypothesis fails to converge and only matches other methods on short times. We see no evidence of long-time tails in either DMT or OST calculations of the current-current correlator, although we cannot rule out that they appear at longer times. We do observe power-law corrections to the energy density correlator. At finite wavelength, we observe a crossover from purely diffusive, overdamped decay of the energy density, to underdamped oscillatory behavior similar to that of cold atom experiments. We dub this behavior "hot band second sound" and offer a microscopically-motivated toy model.
description: 18 pages, 13 figures
MOESM3 of Associations between blood glucose level and outcomes of adult in-hospital cardiac arrest: a retrospective cohort study
Creators: name: Chih-Hung Wang
name: Chien-Hua Huang
name: Wei-Tien Chang
name: Min-Shan Tsai
name: Ping-Hsun Yu
name: Yen-Wen Wu
name: Wen-Jone Chen
Publisher: name: Figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: 60506 Virology

description: Additional file 3: Table S3. Features, interventions, and outcomes of cardiac arrest events stratified by the presence of measurement of blood glucose level after sustained return of spontaneous circulation.
Additional file 6: of Effectiveness of multifaceted implementation strategies for the implementation of back and neck pain guidelines in health care: a systematic review
Creators: name: Suman, Arnela
name: Dikkers, Marije
name: Schaafsma, Frederieke
name: Tulder, Maurits Van
name: Anema, Johannes
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: Computational Biology

description: Appendix B. List of excluded studies and reasons for exclusion. (DOCX 17 kb)
Lecithocera insidians Meyrick 1918
Creators: name: Das, Apurva
name: Pathania, Prakash C.
name: Singh, Navneet
Publisher: name: Zenodo
Year: 2022
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Lepidoptera
Lecithoceridae
Lecithocera
Lecithocera insidians

description: 66. Lecithocera insidians Meyrick, 1918b: 108
Type locality: India, Karnataka, Coorg
Distribution: Indian records: Karnataka.
description: Published as part of Das, Apurva, Pathania, Prakash C. & Singh, Navneet, 2022, A catalogue of Indian Lecithoceridae (Lepidoptera: Gelechioidea), pp. 56-78 in Zootaxa 5165 (1) on pages 66-67, DOI: 10.11646/zootaxa.5165.1.2, http://zenodo.org/record/6825526
Additional file 1: Table S1. of Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites
Creators: name: Jung, Maria
name: PĂźtzer, Svenja
name: Gevensleben, Heidrun
name: Meller, Sebastian
name: Kristiansen, Glen
name: Dietrich, Dimo
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Hematology

description: Clinical performance of DNA methylation analyses in detail. Tumor (organ) specific performance of the developed assay in a retrospective cohort study comprised of ascites from 283 patients with suspected malignant disease including 134 patients with histological confirmed primary cancer. Cell-free DNA was extracted from 162 patients including 81 patients with malignant diseases. (DOC 96 kb)
MOESM1 of Associations between blood glucose level and outcomes of adult in-hospital cardiac arrest: a retrospective cohort study
Creators: name: Chih-Hung Wang
name: Chien-Hua Huang
name: Wei-Tien Chang
name: Min-Shan Tsai
name: Ping-Hsun Yu
name: Yen-Wen Wu
name: Wen-Jone Chen
Publisher: name: Figshare
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics

description: Additional file 1: Table S1. Definitions of comorbidities used in the multivariable models.
Metatrichia
Creators: name: Winterton, Shaun L.
name: Woodley, Norman E.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Diptera
Scenopinidae
Metatrichia

description: Key to extant species of Metatrichia from the New World
1. Legs tan-brown; abdomen generally tan coloured with posterior margins of tergites 1–7 cream-coloured; abdomen without scale-like setae; notopleural region of pleura cream; knob of haltere cream; wings of female hyaline............ .............................................................................................................................................. M. venezuelensis sp. nov.
- Legs very dark brown to black; abdomen black, sometimes with reddish-yellow colour laterally; abdomen with scale-like setae laterally; notopleural region of pleura black; knob of haltere whitish yellow to brown; wings of female with brownish infuscation ................................................................................................................................ 2
2. Body uniformly black, sometimes end of abdomen vaguely brownish in females; knob of haltere primarily brown; widespread in United States to northern Mexico ............................................................... M. bulbosa (Osten Sacken)
- Body largely black, but male abdomen (female unknown) with lateral margins of tergites 3–6 and entire tergite 7 reddish yellow; knob of haltere whitish yellow; known with certainty only from Paraguay ......... M. robusta Kröber
description: Published as part of Winterton, Shaun L. & Woodley, Norman E., 2009, New species of Metatrichia Coquillett (Diptera: Scenopinidae) from Australia and Venezuela, pp. 42-51 in Zootaxa 2094 on page 50, DOI: 10.5281/zenodo.187576
Additional file 1: of Vectors for Genetically-Encoded Tags for Electron Microscopy Contrast in Drosophila
Creators: name: Tsui, Marco
name: Itoh, Anri
name: Amgad, Mohamed
name: Shao-Fang Wang
name: Sasaki, Toshio
Publisher: name: Figshare
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Evolutionary Biology
subject: Developmental Biology
subject: Marine Biology
subject: 110309 Infectious Diseases
subject: FOS: Health sciences
subject: 60506 Virology

description: Supplementary Table 1. Primer sequences. Supplementary Figure 2. Plasmid Maps (DOCX 1425Â kb)