cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Altered metabolism of daunorubicin and doxorubicin by genetic variants of human aldo-keto and carbonyl reductases
Creators: name: Bains, Onkar Singh
Publisher: name: University of British Columbia
Year: 2011

description: The anthracyclines, doxorubicin (DOX) and daunorubicin (DAUN) are commonly used to treat a variety of cancers. Their use is associated with life-threatening adverse events, especially chronic cardiotoxicity, in some patients. There may be a genetic basis for this variation, arising from altered metabolism by non-synonymous single nucleotide polymorphisms (ns-SNPs) in genes encoding for the aldo-keto reductase (AKR) and carbonyl reductase (CBR) enzymes, which are responsible for the biotransformation of these two drugs. The first two studies (Chapters 2 and 3) of this thesis examined the effect of ns-SNPs in 8 AKR and 3 CBR genes on the in vitro metabolism of both anthracyclines to their major metabolites, doxorubicinol (DOXol) and daunorubicinol (DAUNol) using purified, human wild-type and genetic variant enzymes. Michaelis-Menten kinetic curves were plotted and the metabolic capacities of the wild-type and variant enzymes were compared using catalytic efficiency (kcat/Km). In the presence of DAUN, 7 AKR and 5 CBR variants exhibited significantly reduced metabolic activity while 3 AKR and 5 CBR variants demonstrated significantly reduced activity with DOX as substrate. These findings suggest that genetic variants of human AKRs and CBRs are capable of decreasing the in vitro metabolism of DOX and DAUN. There is considerable controversy in the literature on how DAUN and DOX contribute to the variable adverse events seen in patients treated with these drugs. Some studies suggest that the toxic species are the major metabolites, DAUNol and DOXol, while others suggest the parent drug is more toxic. To study this, I examined whether a strong and consistent association exists between metabolic activity and drug toxicity among nine cell lines from different tissues (Chapter 4). My findings indicated that there is a strong, and inversely proportional, association between cytotoxicity and DAUN or DOX metabolism. Furthermore, the cell lines that were resistant to the toxic effects of these drugs had significantly greater expression of the AKRs and CBRs. Overall, these data provide a foundation of biochemical evidence to design in vivo studies that will elucidate the role of altered metabolism by genetic variants of human AKRs and CBRs in the development of anthracycline-induced cardiotoxicity.
Helical buckling of a whirling conducting rod in a uniform magnetic field
Creators: name: Valverde, J.
name: van der Heijden, G. H. M.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 74K10, 74G60

description: We study the effect of a magnetic field on the behaviour of a conducting elastic rod subject to a novel set of boundary conditions that, in the case of a transversely isotropic rod, give rise to exact helical post-buckling solutions. The equations used are the geometrically exact Kirchhoff equations and both static (buckling) and dynamic (whirling) instability are considered. Critical loads are obtained explicitly and are given by a surprisingly simple formula. By solving the linearised equations about the (quasi-)stationary solutions we also find secondary instabilities described by (Hamiltonian-)Hopf bifurcations, the usual signature of incipient `breathing' modes. The boundary conditions can also be used to generate and study helical solutions through traditional non-magnetic buckling due to compression, twist or whirl.
description: arXiv admin note: substantial text overlap with arXiv:0810.3668
NGC 2419 does not challenge MOND
Creators: name: Sanders, R. H.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: I show that, in the context of MOND, non-isothermal models, approximated by high order polytropic spheres, are consistent with the observations of the radial distribution of the line-of-sight velocity dispersion in the distant globular cluster, NGC 2419. This calls into question the claim by Ibata et al. that the object constitutes a severe challenge for MOND. In general, the existence and properties of globular clusters are more problematic for LCDM than for MOND.
description: 3 pages, 2 figrues, minor revisions, programming error corrected, accepted MNRAS
Una aproximación a la legislación sobre perspectiva de familia en cuatro países latinoamericanos: Brasil, Chile, Colombia y México (2000-2021)
Creators: name: Romero Castillo, Ana Margarita
name: Docal Millán, María Del Carmen
Publisher: name: Quaderns de Polítiques Familiars
Year: 2022

description: La contribución de la familia en la formación de valores tales como la cohesión social, la corresponsabilidad, la educación de la participación ciudadana y la construcción de paz social ponen a esta institución en el centro del debate y la cuestión de la construcción del capital social y de un mundo sostenible. La familia es reconocida como una organización clave en el desarrollo de las naciones, sin embargo, en Latinoamérica debido a las transformaciones sociales, económicas y culturales sucedidas en el mundo a partir de la segunda mitad del siglo XX se plantean nuevos retos. En este sentido, la perspectiva de familia en los desarrollos legislativos evidencia la necesidad de un mayor compromiso político. El objetivo de este artículo es identificar mediante una revisión del estado del arte los desarrollos normativos que favorecen a las familias en cuatro países: Brasil, Chile, Colombia y México en los años 2000 al 2021. Para ello se ha seguido una metodología basada en un estudio cualitativo de carácter documental. Como resultados principales cabe destacar la importancia de la normativa sobre conciliación trabajo-familia (work family policies) que presenta el mayor número de leyes y decretos en comparación con otras políticas familiares legisladas referidas al cuidado y al trabajo no remunerado.
description: Quaderns de Polítiques Familiars, Núm. 7: The first decade of building a family-friendly Hungary
Polarimetric Synthetic Aperture Radar Measurements of Snow Covered First-Year Sea Ice
Creators: name: Hossain, Md. Mosharraf
Publisher: name: Graduate Studies
Year: 2012
Subjects: subject: Physical Geography
subject: Physical Oceanography
subject: Remote Sensing
subject: Engineering--Marine and Ocean
subject: Remote Sensing
subject: Physical Geography
subject: Microwave
subject: Polarimetric SAR
subject: Snow Cover
subject: First-Year Sea Ice

description: This study examines the utility of fully polarimetric C-and SAR parameters and three-component scattering model to quantify the sensitivity of snow covered first-year sea ice (FYI) to radar incidence angles and surface air temperature (SAT) during the late winter transition. This three-component scattering model is based on surface, double-bounce and volume scattering contributed from various materials and surface properties. RADARSAT-2 C-band fully polarimetric synthetic aperture radar (POLSAR) data is utilized to quantify the sensitivity of thermodynamic effects (-8° C and -0.4° C ) of the polarimetric backscatter signature on mean snow cover thickness ranging from 8 cm to 36 cm with in-situ geophysical data from four different validation sites along with two different radar incidence angles 29° (steep) and 39° (shallow) to discriminate between snow-covered smooth, rough and deformed FYI. The result shows enhanced discrimination at shallower incidence angles compared to steeper ones in both 2-D and 3-D plots. The double-bounce scattering contribution is low for all FYI types at both incidence angles which are attributed to shallower incidence angle as microwave energy being in direct contact with a greater volume of higher dielectric brine coated, enlarged snow grains in the basal layer compared to the steeper incidence angles. The results also show that surface scattering dominates for all three FYI types at both incidence angles and decreases with increasing surface roughness and radar incidence angles whereas opposite results observed for volume scattering mechanisms. The results indicate that higher variation measured for thin snow class ~7 dB for both co- cross-polarization backscatters compared to thick snow class ~1 dB which corroborates with electro-thermodynamic theory.
On Graphical Modeling of Preference and Importance
Creators: name: Brafman, R. I.
name: Domshlak, C.
name: Shimony, S. E.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: In recent years, CP-nets have emerged as a useful tool for supporting preference elicitation, reasoning, and representation. CP-nets capture and support reasoning with qualitative conditional preference statements, statements that are relatively natural for users to express. In this paper, we extend the CP-nets formalism to handle another class of very natural qualitative statements one often uses in expressing preferences in daily life - statements of relative importance of attributes. The resulting formalism, TCP-nets, maintains the spirit of CP-nets, in that it remains focused on using only simple and natural preference statements, uses the ceteris paribus semantics, and utilizes a graphical representation of this information to reason about its consistency and to perform, possibly constrained, optimization using it. The extra expressiveness it provides allows us to better model tradeoffs users would like to make, more faithfully representing their preferences.
Helsinki Convention
Creators: name: Ombudstvedt, Ingvild
Publisher: name: Zenodo
Year: 2023
Subjects: Legal aspects

description: Convention on the Protection of the Marine Environment of the Baltic Sea Area Legal issues listed: London Protocol
 Transport modalities under the EU ETS
 Lack of incentives for BECCS and DAC
 Helsinki Convention
 EU CCS Directive (Legal)
An analytical approximation of the luminosity distance in flat cosmologies with a cosmological constant
Creators: name: Adachi, Masaru
name: Kasai, Masumi
Publisher: name: arXiv
Year: 2011
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: We present an analytical approximation formula for the luminosity distance in spatially flat cosmologies with dust and a cosmological constant. Apart from the overall factor, the effect of non-zero cosmological constant in our formula is written simply in terms of a rational function. We also show the approximate formulae for the Dyer-Roeder distance (empty beam case) and the generalized angular diameter distance from redshift $z_1$ to $z_2$, which are particularly useful in analyzing the gravitational lens effects. Our formulae are widely applicable over the range of the density parameter and the redshift with sufficiently small uncertainties. In particular, in the range of density parameter $0.3 \leq Ω_{\rm m} \leq 1$ and redshift $0.03 \leq z \leq 1000$, the relative error for the luminosity distance by our formula is always smaller than that of the recent work by Wickramasinghe and Ukwatta (2010). Hence, we hope that our formulae will be an efficient and useful tool for exploring various problems in observational cosmology.
description: 8 pages, 1 figure; version accepted for publication in PTP. arXiv admin note: substantial text overlap with arXiv:1012.2670
Christian Privilege and Oppression in Canadian Public Schools
Creators: name: Knowler, Stephanie
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Education--Curriculum and Instruction
subject: privilege
subject: oppression
subject: multiculturalism
subject: education
subject: religion

description: There is evidence that the Christian religion has privilege in Canadian public schools. This is problematic in a multicultural country where people of various faiths reside. This research ex-plores the manner in which Christian privilege exists and promotes a certain message in public schools. Thirty-two individuals were interviewed, including students, parents, educators and administrators in an effort to access many experiences. Using thematic analysis, specific themes emerged and were examined and categorized. Findings support that there is a place for religion in public schools, but not when it marginalizes or inflicts specific beliefs onto anyone, particularly students. Instead, teaching about religion from a non-biased perspective should be included as meaningful and purposeful instruction. A multicultural model of education is pro-posed in order to create safe schools grounded on inclusion, and offer meaningful instruction where many world views are embraced, challenged and celebrated in order to create informed global citizens.
title: Praxisgerichtete Forschung am Beispiel der Bahndehnungsmessung
Creators: name: Scheuter, Karl R.
Publisher: name: UNSPECIFIED
Year: 1981

description: Es wurden die physikalisch-drucktechnischen Zusammenhänge dargelegt, welche zu der für die Praxis bedeutsamen Forderung führen, die allgemein übliche Bahnspannungsregelung in Rollen-Rotationsdruckmaschinen für hohe Qualitätsforderungen durch eine Bahndehnungsregelung zu ersetzen. Es wurde im weiteren auf die Problemlösung und die dabei zu überwindenden Schwierigkeiten eingegangen und eine Lösungsmöglichkeit erwähnt, welche zur Planung eines Forschungsvorhabens zur Entwicklung einer Einrichtung zur Bahndehnungsmessung und -regelung führte.
Exploring the aspects of Upskilling and Education on Citizen Science
Creators: name: Karaiskou, Theodora
name: Cassella, Maria
name: Martek, Alisa
name: Vrcon, Andrej
name: Dakić, Nataša
name: Mumelaš, Dolores
Publisher: name: Zenodo
Year: 2023

description: This workshop, initiated by the Erasmus+ CeOS_SE project of LIBER, is focusing on the ways that Citizen Science is getting the attention of the relevant stakeholders, equips them with knowledge and skills, and secures its long-term sustainability. Upskilling and educating are crucial activities that libraries often undertake within their institutions and beyond. Having the essential knowledge of Citizen Science, enables one to take the best decisions and to be effective during the delivery of services. Therefore, the need of highly skilled information professionals is imperative and this requires not only the upskilling of the current workforce, but also of the young, new librarians. The participants will be expected to learn about the skills and competencies that are required to perform CS activities and services. They will also have the opportunity to provide their own input about the skills that information and library professionals should have to perform effectively their CS-related tasks.
Gemeinsam statt einsam: Beispiele für ein vernetztes Forschungsdatenmanagement
Creators: name: Netscher, Sebastian
Publisher: name: Zenodo
Year: 2020
Subjects: research data management
network

description: The presentation was given as part of the networking meeting Research Data Management Reloaded: Open Data and the Future of Research Data Management in the Social Sciences and Humanities that targeted research data management officers of universities, academic libraries and research institutes in German-speaking countries. The meeting involved a review of Open Data requirements and related infrastructures, e.g. in terms of best practice guidelines or data repositories, as well as of resources to assist researchers in processing Open Data, such as the FOSTER Plus Online Toolkit or the CESSDA Data Management Expert Guide.The meeting was part of the FOSTER Plus Project (Facilitate Open Science Training For European Research), funded by the EU (grant numbers 612425 and 741839). It took place on April 24th and 25th, 2019, at GESIS – Leibniz-Institute for the Social Sciences in Cologne, Germany. The course’s language was German. It was supported by CESSDA Training, being a follow-up event of the CESSDA’s Train- the-Trainers workshop in Ljubljana in April 2018.

 Sebastian Netscher gave three examples of integrated research data management networks. The workshop consisted of several presentations: Introduction “Open Science und FAIR Data” http://doi.org/10.5281/zenodo.3925299 Das FOSTER Toolkit http://doi.org/10.5281/zenodo.3925327 CESSDA Data Management Expert Guide: Forschungsdatenmanagement Training Tool https://doi.org/10.5281/zenodo.3964385 Was bietet das GESIS Datenarchiv an? http://doi.org/10.5281/zenodo.3925380 Gemeinsam statt einsam: Beispiele für ein vernetztes Forschungsdatenmanagement http://doi.org/10.5281/zenodo.3925390 Hessische Forschungsdateninfrastruktur HeFDI- FDM als Landesinitiative http://doi.org/10.5281/zenodo.3925395 Verbund Forschungsdaten Bildung http://doi.org/10.5281/zenodo.3925399 CESSDA ERIC: Ein paneuropäisches Netzwerk sozialwissenschaftlicher Datenarchive http://doi.org/10.5281/zenodo.3925409
Pressure dependent electronic properties of MgO polymorphs: A first-principles study of Compton profiles and autocorrelation functions
Creators: name: Joshi, K. B.
name: Sharma, B. K.
name: Paliwal, U.
name: Barbiellini, B.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The first-principles periodic linear combination of atomic orbitals method within the framework of density functional theory implemented in the CRYSTAL06 code has been applied to explore effect of pressure on the Compton profiles and autocorrelation functions of MgO. Calculations are performed for the B1, B2, B3, B4, B8_1 and h-MgO polymorphs of MgO to compute lattice constants and bulk moduli. The isothermal enthalpy calculations predict that B4 to B8_1, h-MgO to B8_1, B3 to B2, B4 to B2 and h-MgO to B2 transitions take place at 2, 9, 37, 42 and 64 GPa respectively. The high pressure transitions B8_1 to B2 and B1 to B2 are found to occur at 340 and 410 GPa respectively. The pressure dependent changes are observed largely in the valence electrons Compton profiles whereas core profiles are almost independent of the pressure in all MgO polymorphs. Increase in pressure results in broadening of the valence Compton profiles. The principal maxima in the second derivative of Compton profiles shifts towards high momentum side in all structures. Reorganization of momentum density in the B1 to B2 structural phase transition is seen in the first and second derivatives before and after the transition pressure. Features of the autocorrelation functions shift towards lower r side with increment in pressure.
description: 19 pages, 8 figures, accepted for publication in Journal of Materials Science
East African Immigrant Women with Gestational Diabetes Mellitus: A Mixed-methods Evaluation of the Care Experience in a Vulnerable Population
Creators: name: Siad, Fartoon
Publisher: name: Graduate Studies
Year: 2016
Subjects: subject: Education--Health
subject: Public Health
subject: Gestational diabetes, immigrant women, East Africa, health education, care experience, diabetes, post-partum screening.

description: Background: Low rates of post-partum diabetes screening continues to impact the health of immigrant women diagnosed with gestational diabetes and high-risk for the development of future diabetes. The objectives of this study were to explore the diabetes resources available in Calgary and the care experiences of immigrant women. Methods: An online survey was distributed to six health clinics and community organizations involved in the provision of diabetes services to immigrant women. Ten East African women with gestational diabetes were identified and interviewed. Interviews were transcribed verbatim and thematically analyzed. Conclusion: The findings of this thesis suggest that current approaches to diabetes education and care in East African women with GDM lack cultural relevance to this high-risk community and do not emphasize the need for ongoing post-partum screening. Diabetes prevention using innovative community-level interventions such as patient navigators and care that engages and empowers women as partners in health are needed. Key words: Gestational diabetes, immigrant women, East Africa, health education, care experience, diabetes, post-partum screening.
Computational approaches for empirical Bayes methods and Bayesian sensitivity analysis
Creators: name: Buta, Eugenia
name: Doss, Hani
Publisher: name: arXiv
Year: 2012
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We consider situations in Bayesian analysis where we have a family of priors $ν_h$ on the parameter $θ$, where $h$ varies continuously over a space $\mathcal{H}$, and we deal with two related problems. The first involves sensitivity analysis and is stated as follows. Suppose we fix a function $f$ of $θ$. How do we efficiently estimate the posterior expectation of $f(θ)$ simultaneously for all $h$ in $\mathcal{H}$? The second problem is how do we identify subsets of $\mathcal{H}$ which give rise to reasonable choices of $ν_h$? We assume that we are able to generate Markov chain samples from the posterior for a finite number of the priors, and we develop a methodology, based on a combination of importance sampling and the use of control variates, for dealing with these two problems. The methodology applies very generally, and we show how it applies in particular to a commonly used model for variable selection in Bayesian linear regression, and give an illustration on the US crime data of Vandaele.
description: Published in at http://dx.doi.org/10.1214/11-AOS913 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
title: Framework for Wildfire Danger Prediction System
Creators: name: Dobrinkova, Nina
name: Asenova, Maria
Publisher: name: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 259-270
Year: 2020
Subjects: subject: FOS: Computer and information sciences

description: Wildland fires are natural hazard that occur every year in different parts of the world. European Mediterranean countries often are suffering from this disaster and in some cases human casualties plus infrastructure damages are in place. Bulgaria as part of the north east Mediterranean basin is affected by wildland fires in the last three decades more often than before. In our article we will present a framework for wildfire danger prediction system by usage of wireless sensor networks collecting real data and elaborating it into alerts. The test area is located on the territory of South-West state-owned forestry district. The described approach is based on the national fire danger rating algorithm, but in our case downscaled to daily prognosis. The system is under construction at the time of the paper writing thus the framework of the system main functionalities is the main scope of the article.
description: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 259-270
Direct and Indirect Effects of Sequential Treatments
Creators: name: Didelez, Vanessa
name: Dawid, Philip
name: Geneletti, Sara
Publisher: name: arXiv
Year: 2012
Subjects: subject: Methodology (stat.ME)
subject: FOS: Computer and information sciences

description: In this paper we review the notion of direct causal effect as introduced by Pearl (2001). We show how it can be formulated without counterfactuals, using intervention indicators instead. This allows to consider the natural direct effect as a special case of sequential treatments discussed by Dawid and Didelez (2005) which immediately yields conditions for identifiability as well as a graphical way of checking identifiability. The results are contrasted with the criteria given by Pearl (2001) and Robins (2003).
description: Appears in Proceedings of the Twenty-Second Conference on Uncertainty in Artificial Intelligence (UAI2006)
Homoclinic Orbits of the FitzHugh-Nagumo Equation: Bifurcations in the Full System
Creators: name: Guckenheimer, John
name: Kuehn, Christian
Publisher: name: arXiv
Year: 2012
Subjects: subject: Dynamical Systems (math.DS)
subject: Numerical Analysis (math.NA)
subject: Chaotic Dynamics (nlin.CD)
subject: Neurons and Cognition (q-bio.NC)
subject: FOS: Mathematics
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: This paper investigates travelling wave solutions of the FitzHugh-Nagumo equation from the viewpoint of fast-slow dynamical systems. These solutions are homoclinic orbits of a three dimensional vector field depending upon system parameters of the FitzHugh-Nagumo model and the wave speed. Champneys et al. [A.R. Champneys, V. Kirk, E. Knobloch, B.E. Oldeman, and J. Sneyd, When Shilnikov meets Hopf in excitable systems, SIAM Journal of Applied Dynamical Systems, 6(4), 2007] observed sharp turns in the curves of homoclinic bifurcations in a two dimensional parameter space. This paper demonstrates numerically that these turns are located close to the intersection of two curves in the parameter space that locate non-transversal intersections of invariant manifolds of the three dimensional vector field. The relevant invariant manifolds in phase space are visualized. A geometrical model inspired by the numerical studies displays the sharp turns of the homoclinic bifurcations curves and yields quantitative predictions about multi-pulse and homoclinic orbits and periodic orbits that have not been resolved in the FitzHugh-Nagumo model. Further observations address the existence of canard explosions and mixed-mode oscillations.
description: preprint version - for final version please see journal reference
Population Genetics of Athabasca River Basin Bull Trout (Salvelinus confluentus)
Creators: name: Carroll, Emma
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Ecology
subject: FOS: Biological sciences
subject: Bull Trout
subject: conservation
subject: population genetics

description: Across its native range, Bull Trout (Salvelinus confluentus) extent and abundance are in decline due to historic overharvest, invasive species and habitat degradation. These factors inhibit Bull Trout recovery and can lead to negative genetic consequences. To establish baseline population genetic understanding of Bull Trout in the Athabasca River Basin, 431 Bull Trout from 20 sites across Alberta’s Eastern slopes were sampled, and compared using 10 microsatellite loci to characterize within- and among-population genetic variation. The Saskatchewan and Athabasca River basins contained similar levels of heterozygosity but were differentiated from one another, suggesting that Bull Trout in the watersheds have similar genetic diversity, but are genetically differentiated from one another. Within the Athabasca River basin, five genetically differentiated clusters were identified. Additionally, no ‘Isolation By Distance’ pattern was found between sites, suggesting that some near populations are genetically differentiated while some distant populations are genetically similar to one another.
Impurity Entanglement in the $J-J_2-δ$ Quantum Spin Chain
Creators: name: Deschner, Andreas
name: Sorensen, Erik S.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The contribution to the entanglement of an impurity attached to one end of a $J-J_2-delta$ quantum spin chain (S=1/2) is studied. Two different measures of the impurity contribution to the entanglement have been proposed: the impurity-entanglement-entropy S_{imp} and the negativity N. The first, S_{imp}, is based on a subtractive procedure where the entanglement-entropy in the absence of the impurity is subtracted from results with the impurity present. The other, N, is the negativity of a part of the system separated from the impurity and the impurity itself. In this paper we compare the two measures and discuss similarities and differences between them. In the $J-J_2-δ$ model it is possible to perform very precise variational calculations close to the Majumdar-Ghosh-point (J_2 = J / 2 and δ= 0) where the system is gapped with a two-fold degenerate dimerized ground-state. We describe in detail how such calculations are done and how they can be used to calculate N as well as S_{imp} for any impurity-coupling J_K. We then study the complete cross-over in the impurity entanglement as J_K is varied between 0 and 1 close to the Majumdar-Ghosh-point. In particular we study the impurity entanglement when a staggered nearest-neighbour-interaction proportional to $δ$ is introduced. In this case, the two-fold degeneracy of the ground-state is lifted leading to a very rapid reduction in the impurity entanglement as $δ$ is increased.
description: 24 pages, 25 figures, typos corrected, one figure added and minor revisions of text performed
title: Evaluation of Sentinel-3a OLCI Ocean Color Products in the Western Black Sea
Creators: name: Slabakova, Violeta
name: Moncheva, Snejana
name: Slabakova, Natalyia
name: Dzhembekova, Nina
Publisher: name: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 271-281
Year: 2020
Subjects: subject: FOS: Computer and information sciences

description: Ocean color remote sensing has entered a new era with the successful launch of the Ocean and Land Colour Instrument (OLCI) on board Copernicus Sentinel-3 satellites. The representativeness and accuracy of the OLCI geophysical products are poorly quantified in the Black Sea which is featured by high bio-optical complexity. This paper addresses the evaluation of the OLCI/3A sensor’s performance for retrieving ocean color products of the western Black Sea waters, by carrying out qualitative and quantitative match-up analysis between in situ and OLCI data. Results indicate a systematic underestimate of the water-leaving radiances (more pronounced at 412 and 665 nm) in contrary to the OLCI standard Chlorophyll (CHL) products which significantly overestimate the in situ records. These findings confirm the need of consistent reference in situ bio-optical data with improved spatial and temporal coverage for further satellite ocean color missions calibration and validation activities in the Black Sea.
description: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 271-281
"My journey from research to data stewardship: a new career pathway for parents in science" - IEEE WIE International LS - Virtual Event, Dec 15 2020
Creators: name: Pasquale, Valentina
Publisher: name: Zenodo
Year: 2020
Subjects: open science
data stewardship
women in science
data management

description: Slide presentation "My journey from research to data stewardship: a new career pathway for parents in science" by Valentina Pasquale at the IEEE WIE International Leadership Summit (ILS) Virtual Event, on December 15th 2020.
Solid state NMR investigations of protein based biomaterials: spider silk, recombinant spider silk proteins, and electrospun spider silk proteins
Creators: name: Katz, David Samuel
Publisher: name: University of British Columbia
Year: 2010

description: ¹³C Nuclear Magnetic Resonance was employed to investigate the structure of spider dragline silk, powdered recombinant major ampulate spidroin 1 (MaSp1) and 2 (MaSp2) that were produced in the milk of genetically engineered goats, and electrospun MaSp1. Cross polarization spectra were used to assign secondary structures to the protein residues, and longitudinal relaxation measurements were used to investigate the molecular thermal motion. The crystalline regions of spider silk were found to exhibit nanosecond scale thermal motion, subject to very rigid motional limits. The recombinant MaSp1 and MaSp2 were found to have very similar structures that exhibited abundant β sheet crystalline regions. Electrospun MaSp1 however appears to be highly disordered and is perhaps best characterized as denatured. These results are in contrast to previous findings of spider silk proteins in non-fiber states, where no appreciable crystalline component was observed, and appears to be inconsistent with previous Fourier transform infrared spectroscopy of similarly prepared samples. Reconsideration of the FTIR data however raises concerns about the interpretation of those data, possibly explaining the disagreement. This work suggests that the lack of regular structure found in the electrospun MaSp1 is the cause of the very poor mechanical properties previously measured for this material.
The Planning Spectrum - One, Two, Three, Infinity
Creators: name: Pistore, M.
name: Vardi, M. Y.
Publisher: name: arXiv
Year: 2011
Subjects: subject: Artificial Intelligence (cs.AI)
subject: FOS: Computer and information sciences

description: Linear Temporal Logic (LTL) is widely used for defining conditions on the execution paths of dynamic systems. In the case of dynamic systems that allow for nondeterministic evolutions, one has to specify, along with an LTL formula f, which are the paths that are required to satisfy the formula. Two extreme cases are the universal interpretation A.f, which requires that the formula be satisfied for all execution paths, and the existential interpretation E.f, which requires that the formula be satisfied for some execution path. When LTL is applied to the definition of goals in planning problems on nondeterministic domains, these two extreme cases are too restrictive. It is often impossible to develop plans that achieve the goal in all the nondeterministic evolutions of a system, and it is too weak to require that the goal is satisfied by some execution. In this paper we explore alternative interpretations of an LTL formula that are between these extreme cases. We define a new language that permits an arbitrary combination of the A and E quantifiers, thus allowing, for instance, to require that each finite execution can be extended to an execution satisfying an LTL formula (AE.f), or that there is some finite execution whose extensions all satisfy an LTL formula (EA.f). We show that only eight of these combinations of path quantifiers are relevant, corresponding to an alternation of the quantifiers of length one (A and E), two (AE and EA), three (AEA and EAE), and infinity ((AE)* and (EA)*). We also present a planning algorithm for the new language that is based on an automata-theoretic approach, and study its complexity.
The Signaling Mechanisms Involved in Ca2+ Wave Generation and Myogenic Tone Regulation in Cerebral Arteries
Creators: name: Mufti, Rania Ezzat
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Physiology
subject: FOS: Biological sciences
subject: Cerebral Blood Flow Regulation

description: In the cerebral vasculature, the myogenic response plays an essential role in maintaining constant blood flow in an environment where intravascular pressure is constantly changing. This key biological response depends in part on a rise in cytosolic [Ca2+], an event often ascribed to arterial depolarization and the activation of voltage gated Ca2+ channels. While extracellular Ca2+ influx is important, a role for internal SR store release remains uncertain. The overall objective of this thesis was to clarify the mechanistic relationship between intravascular pressure, SR Ca2+ wave mobilization, cellular signaling and myogenic tone development. In the first of three defined goals, we showed for the first time that elevated intravascular pressure mobilizes SR Ca2+ waves in a voltage-insensitive manner. It was further noted that these SR-driven events contribute to MLC20 phosphorylation and tone development by modulating both MLCK and MLCP activity. The second goal focused on upstream signaling and the role of αvβ3-integrins in “sensing” intravascular pressure. More specifically, our work revealed that blocking this specific integrin receptor not only attenuated Ca2+ wave generation but also MLC20 phosphorylation and myogenic tone development. The final goal revealed that αvβ3-integrins facilitate pressure-induced Ca2+ waves and tone development by mobilizing downstream signaling proteins that included PLCγ1 and IP3R proteins. Overall, the findings arising from the three goals highlighted the mechanistic basis of pressure-inducing Ca2+ wave generation and myogenic tone development in resistance vasculature. This in turn will enlighten experimental approaches to control cerebral blood flow and will also provide crucial insight to treat cerebrovascular disease.
Variance and Volatility Swaps and Futures Pricing Under Geometric Markov Renewal Processes and Stochastic Volatility Models
Creators: name: Wang, Zijia
Publisher: name: Graduate Studies
Year: 2017
Subjects: subject: Education--Finance
subject: Mathematics
subject: FOS: Mathematics
subject: variance and volatility swaps
subject: geometric Markov renewal process
subject: VIX futures

description: In this thesis, we consider volatility swap, variance swap and VIX future pricing under different asset models. Specifically, we obtain the new results of swaps and futures pricing for the geometric Markov renewal processes (GMRP) models under different schemes and approximation approaches. We also consider four different stochastic volatility models and jump diffusion models which are commonly used in financial market, and use convexity correction approximation technique and Laplace transform method to evaluate the variance and volatility strikes and estimate the VIX future prices. In empirical study, we use Markov chain Monte Carlo algorithm for model calibration based on S&P 500 market data, evaluate the effect of adding jumps into the asset price processes on volatility derivatives pricing, and compare the performance of different pricing approaches.
title: A Modelling System for Numerical Weather Prediction in the Bulgarian Antarctic Base Area
Creators: name: Chtirkova, Boriana
name: Peneva, Elisaveta
name: Georgieva, Gergana
Publisher: name: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 282-296
Year: 2020
Subjects: subject: FOS: Computer and information sciences

description: The weather forecast of good quality is essential for the humans living and operating in the Bulgarian Antarctic Base (BAB), located on the Livingstone Island coast at 62.64⁰ S and 60.36⁰ W. The numerical weather prediction models in southern high latitude regions still need improvement as the user community is limited, little test cases are documented and validation data are scarce. The modelling system is based on the WRF model, configured in three nested domains down to 1 km horizontal resolution, centered over BAB. The main objective of the study is to configure and validate the WRF model and to recommend certain set-up parameters like model area coverage, topography, land use, vertical levels, physics parametrization schemes, preparation of initial and boundary conditions and run configuration on HPC machines. Three test periods of “bad” weather events are considered during the summer seasons in 2016, 2017 and 2020. The ability of the 3 days forecast to capture the basic meteorological events in this period is discussed. Sensitivity experiments to the land use type are conducted and while the MODIS land data is found to be the most accurate for the region, a slight increase in the soil thermal capacity results in better model performance.
description: Proceeding of 1st International Conference on Environmental Protection and Disaster RISKs, 2020, p. 282-296
A survey of the informational needs of decision makers for the design and evaluation of trauma systems in Canada
Creators: name: Evans, David C.
Publisher: name: University of British Columbia
Year: 2010

description: BACKGROUND. Across Canada there are substantial differences in the organization and evaluation of regional trauma systems. The design, evaluation and improvement of trauma care is frustrated by variable definitions of trauma systems, their primary objectives, and preferred performance measures. Tools that support decision makers in design and policy development are needed 2, 3. OBJECTIVE. This research aimed to 1) describe decision makers’ perceptions of the scope and objectives of ideally organized regional systems of trauma care and injury control in Canada, and 2) identify decision makers’ informational needs, specifically with regard to performance measures meaningful as actionable guidance for the design and policy development of regional systems of trauma care and injury control. METHODS. Based on a literature review of commonly used trauma system performance measures, a 35-question structured electronic survey was constructed, vetted by a reference group of experts, tested, and circulated over a 3-week period. The framing sample was 342 health administrators and trauma directors self-reported to be involved in decision making for organized injury management and control from all health regions of Canada. Survey responses were collated and descriptive statistics generated. RESULTS. There were 82 complete responses for a response rate of 24.0%. There was strong support for a broadly inclusive definition of a trauma system and for government oversight using standard performance indicators. Among responders there was near equal support, 41.2% and 31.7% respectively, for ensuring delivery of rapid and appropriate care (processes of care) and minimizing individual and societal burden of injury (outcomes of care) as the overarching drivers of system design. Of 24 listed performance indicators, measures of timeliness of care, preventable deaths, severity-adjusted hospital mortality, safety, satisfaction and access to care were preferred. CONCLUSION. This study showed that decision makers responsible for regional trauma systems in Canada believe that the ideal trauma system should coordinate multiple agencies influential in injury management around clear system objectives that address both major and minor trauma, and that government endorsed national standards are needed to ensure efficient and effective processes that reduce the individual and societal burden of injury.
Executive Summary: WORKING TOGETHER; A Landscape Analysis to Inform Practical, Innovative, and Beneficial Use of NASA Earth Science Data to Advance Equity and Environmental Justice in the Gulf South Region
Creators: name: Dr. Beverly Wright
name: Dr. David Padgett
name: Morrow, Nathan
Publisher: name: Zenodo
Year: 2023

description: Executive Summary: This Landscape Analysis intends to inform longer-term NASA Earth Science Division equity and environmental justice (EEJ) efforts and Applied Sciences Program’s EEJ-oriented application activities. A context analysis summarizes relevant background and trends in EJ activism and scholarship, EJ policy development, hazards of the Gulf South in relation to climate change, open community-engaged science, NASA data, and NASA EEJ initiatives. Impact case studies of EJ networks’ Communiversity action research and results of participatory EJ network convenings are presented in synthetic findings of 1) EJ priorities and 2) strategic NASA Earth science engagement opportunities.
Does affective polarization erode winners’ restraint and losers’ consent? Experimental evidence from the 2023 Spanish general elections
Creators: name: Loriente, Mariano Torcal
name: Bonsfills, Josep Maria Comellas
Publisher: name: OSF Registries
Year: 2027
Subjects: subject: Political Science
subject: FOS: Political science
subject: Social and Behavioral Sciences

description: This study aims to assess the extent to which affective polarization undermines the capacity of both 'government winners' and 'government losers' to resist potential undemocratic actions initiated by their party elites. To address this, we will conduct a survey experiment in Spain, examining whether voters prioritize their partisan inclinations over explicitly supporting democratic principles or actions.
Cascade Effects on Circular Arc Airfoils for Windmill Analysis
Creators: name: Fagbenro, Kabir Ayodeji
Publisher: name: Graduate Studies
Year: 2013
Subjects: subject: Energy
subject: Engineering--Aerospace
subject: Engineering--Mechanical
subject: Cascade
subject: Solidity
subject: SST-transition
subject: FLUENT
subject: Windmill

description: Water-pumping is one of the oldest uses of wind energy with the multi-bladed, high-solidity windmill still in widespread use. For the present, solidity can be taken as the projected area of the blades as a fraction of the circular swept area of the rotor. Windmills rotate slowly and have very high solidity, making their aerodynamic analysis fundamentally different to that for modern wind turbines. The main difference addressed in this thesis is solidity effects on blade lift and drag in the expectation that windmills can analysed by a modification of standard blade element theory which assumes that the blades behave as airfoils. Circular arc airfoils were computationally modelled by using the well-known shear stress transport - transition (SST- transition) model in FLUENT to study the solidity effect on lift and drag at Reynolds number of 100,000. The transition model constants were adjusted in order to match measured pressure distributions on isolated circular arc airfoils. The cascade calculations shows that ratio of the lift and drag ratio which measures the performance of the windmill changes significantly with increasing solidity which implies that it should not be neglected in evaluation of windmill performance.
Hessische Forschungsdateninfrastruktur HeFDI - FDM als Landesinitiative
Creators: name: Schumann, Natascha
Publisher: name: Zenodo
Year: 2020
Subjects: research data management

description: The presentation was given as part of the networking meeting Research Data Management Reloaded: Open Data and the Future of Research Data Management in the Social Sciences and Humanities that targeted research data management officers of universities, academic libraries and research institutes in German-speaking countries. The meeting involved a review of Open Data requirements and related infrastructures, e.g. in terms of best practice guidelines or data repositories, as well as of resources to assist researchers in processing Open Data, such as the FOSTER Plus Online Toolkit or the CESSDA Data Management Expert Guide.The meeting was part of the FOSTER Plus Project (Facilitate Open Science Training For European Research), funded by the EU (grant numbers 612425 and 741839). It took place on April 24th and 25th, 2019, at GESIS – Leibniz-Institute for the Social Sciences in Cologne, Germany. The course’s language was German. It was supported by CESSDA Training, being a follow-up event of the CESSDA’s Train- the-Trainers workshop in Ljubljana in April 2018.

 Natascha Schumann introduces the Hessische Forschungsdateninfrastrukturen (HeFDI), which is a network of universities (of applied science) in Hesse (Germany), bringing together research data management officers from all
 academic disciplines. The workshop consisted of several presentations: Introduction “Open Science und FAIR Data” http://doi.org/10.5281/zenodo.3925299 Das FOSTER Toolkit http://doi.org/10.5281/zenodo.3925327 CESSDA Data Management Expert Guide: Forschungsdatenmanagement Training Tool https://doi.org/10.5281/zenodo.3964385 Was bietet das GESIS Datenarchiv an? http://doi.org/10.5281/zenodo.3925380 Gemeinsam statt einsam: Beispiele für ein vernetztes Forschungsdatenmanagement http://doi.org/10.5281/zenodo.3925390 Hessische Forschungsdateninfrastruktur HeFDI- FDM als Landesinitiative http://doi.org/10.5281/zenodo.3925395 Verbund Forschungsdaten Bildung http://doi.org/10.5281/zenodo.3925399 CESSDA ERIC: Ein paneuropäisches Netzwerk sozialwissenschaftlicher Datenarchive http://doi.org/10.5281/zenodo.3925409