cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
The Quantity and Quality of Illegally Imported Products of Animal Origin in Personal Consignments into the European Union Seized at Two German Airports between 2010 And 2014
Creators: name: Jansen, Wiebke
name: Merkle, Majella
name: Daun, Anna
name: Flor, Matthias
name: Grabowski, Nils Th.
name: Klein, Günter
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: The import of products of animal origin (POAO) in travellers’ personal consignments presents a considerable risk of introducing animal diseases and emerging zoonoses into the European Union. The current regulation (EU) 206/2009 implements strict measures for illegally imported POAO, whereupon non-complying products have to be seized and destroyed regardless. Especially airports serve as global bottlenecks for illegally imported POAO where passenger controls of non-European flights are performed by customs and veterinary services in collaboration. Results of these control measures have to be submitted in the form of annual reports to the European Commission. However, few data on qualities and quantities of seizures have been published so far. In this study, POAO seized at two German airports between 2010 and 2014 were analysed in terms of quantities, qualitative categories and region of origin. In most years considered, more than 20 tonnes POAO were seized at each airport. However, reported amounts of seizures seem to be only the tip of the iceberg as an all-passenger control is not feasible and therefore travellers are only spot-checked. The analysis suggests that the organisational structures of both customs and official veterinary services and their different risk perceptions interfere in completing an effective ban on the illegal import of POAO.
“It’s My Story, and by God I’m Going To Tell It”: Perspectives of Lived Experience Disability Educators on Instagram
Creators: name: Cheetham, Alexander Jonathan Lopez
Publisher: name: Brandeis University
Year: 2024
Subjects: Educators
Social Media
People with Disabilities

description: Content creators who are themselves disabled and post primarily educational content about disability, known as Lived Experience Disability Educators (LEDEs), fill a unique and important niche on Instagram. While their journeys may have some overlap with other, previously studied, content creators, their experiences differ in key ways as well due to their status as marginalized individuals speaking openly on their experiences living with a marginalized identity. The Instagram algorithm is complex and often pushes LEDE content to users outside of their followers and outside of their target demographic resulting in an experience of vulnerable virality. As a result of this, LEDEs receive feedback to their work at the extreme ends of human feeling and emotion. Much of this feedback is harmful and damaging, but that the communities LEDEs build online and the positive feedback which allows them to see the impact of their work in real time motivates them to keep creating. Additionally, even when branching out and engaging in work opportunities outside of their Instagram platforms, LEDEs utilize the benefits provided by their digital work to generate many of these engagements and as a hosting site for proof of their multi-faceted work.
Advancements in I​mplantable ​M​e​d​​i​ca​l Devices: A Comprehensive Analysis of Artificial Intelligence Integration, Adoption, and Applicability in Bio-Tech Innovations.
Creators: name: Leocadio, Paulo
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460299
subject: Artificial intelligence not elsewhere classified
classificationCode: 320602
subject: Medical biotechnology diagnostics (incl. biosensors)
classificationCode: 400905
subject: Electronic instrumentation
classificationCode: 400904
subject: Electronic device and system performance evaluation, testing and simulation
classificationCode: 400902
subject: Digital electronic devices
classificationCode: 400906
subject: Electronic sensors
classificationCode: 400908
subject: Microelectronics

description: ​This article offers a comprehensive analysis of the integration, adoption, and applicability of Artificial Intelligence (AI) in the realm of implantable medical devices. Moving beyond singular case studies, ​including BIOTRONIK's notable contributions (BIOTRONIK SE & Co. KG, 2023), this study takes a global perspective, encompassing various manufacturers, researchers, and diverse innovations within the biotech industry. The article begins by examining the intersection of AI and implantable medical devices, recognizing the ​transformative impact of AI technologies on healthcare. Highlighting the indispensable role of AI in advancing biotech innovations, the study emphasizes the potential to revolutionize patient care through real-time insights, predictive analytics, and adaptive functionalities. The purpose of this research is to conduct a thorough and nuanced analysis of the current state of AI integration in implantable medical devices, extending beyond specific manufacturers to include a diverse array of global advancements. Drawing insights from varied researchers and published articles, ensures a diverse and scholarly foundation for the analysis. The scope of coverage spans from general trends in AI and healthcare, as documented by (avcontentteam, 2023), to specific case studies of AI-integrated implantable devices from multiple sources. A comparative analysis critically assesses the strengths and weaknesses of these devices, offering insights into the competitive and complementary aspects of their functionalities. In conclusion, this article contributes to the scholarly discourse surrounding AI in biotech, presenting insights that may shape the trajectory of future research and development in the field. The synthesis of diverse perspectives and innovations provides a holistic understanding of the achievements and challenges within the broader context of AI integration in implantable medical devices.
Advancements in I​mplantable ​M​e​d​​i​ca​l Devices: A Comprehensive Analysis of Artificial Intelligence Integration, Adoption, and Applicability in Bio?Tech Innovations.
Creators: name: Leocadio, Paulo
Publisher: name: figshare
Year: 2024
Subjects: classificationCode: 460299
subject: Artificial intelligence not elsewhere classified
classificationCode: 320602
subject: Medical biotechnology diagnostics (incl. biosensors)
classificationCode: 400905
subject: Electronic instrumentation
classificationCode: 400904
subject: Electronic device and system performance evaluation, testing and simulation
classificationCode: 400902
subject: Digital electronic devices
classificationCode: 400906
subject: Electronic sensors
classificationCode: 400908
subject: Microelectronics

description: ​This article offers a comprehensive analysis of the integration, adoption, and applicability of Artificial Intelligence (AI) in the realm of implantable medical devices. Moving beyond singular case studies, ​including BIOTRONIK's notable contributions (BIOTRONIK SE & Co. KG, 2023), this study takes a global perspective, encompassing various manufacturers, researchers, and diverse innovations within the biotech industry. The article begins by examining the intersection of AI and implantable medical devices, recognizing the ​transformative impact of AI technologies on healthcare. Highlighting the indispensable role of AI in advancing biotech innovations, the study emphasizes the potential to revolutionize patient care through real-time insights, predictive analytics, and adaptive functionalities. The purpose of this research is to conduct a thorough and nuanced analysis of the current state of AI integration in implantable medical devices, extending beyond specific manufacturers to include a diverse array of global advancements. Drawing insights from varied researchers and published articles, ensures a diverse and scholarly foundation for the analysis. The scope of coverage spans from general trends in AI and healthcare, as documented by (avcontentteam, 2023), to specific case studies of AI-integrated implantable devices from multiple sources. A comparative analysis critically assesses the strengths and weaknesses of these devices, offering insights into the competitive and complementary aspects of their functionalities. In conclusion, this article contributes to the scholarly discourse surrounding AI in biotech, presenting insights that may shape the trajectory of future research and development in the field. The synthesis of diverse perspectives and innovations provides a holistic understanding of the achievements and challenges within the broader context of AI integration in implantable medical devices.
Trinidad Muslims in Canada: A community in transition.
Creators: name: Buckridan, Rakib.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Religion, General.

description: This research project sought to obtain information through a mailed questionnaire on various issues and problems encountered by Muslims of Trinidad ancestry in transition as they settle into the Canadian environment. The results indicate there is a core of non-negotiable elements which are held firm. For example: all respondents claim belief in the oneness of God and Muhammed as His prophet (--the testimony of faith that defines the Muslim); the Quran is the revealed word of God to Muhammad; acceptance of the Quran and some or all of the Hadith; there is life after death; angels exist; and that Christianity and Judaism are also acceptable to God. At the same time, several aspects of their religious practices appear negotiable, perhaps for survival or simply getting along in the larger society. The frequency distribution of responses indicates, for example, that the socio-cultural environment in Canada tends to hinder the exercise of some basic injunctions. Political or governmental agencies may find it of interest to note concerns related to finding suitable education for children (including facilities for the imparting of Islamic instruction, Arabic and Urdu or Hindustani languages), obtaining proper burial sites, avoiding religious and racial prejudices. Also problematic are efforts geared at maintaining the extended family with parents and elders held in high respect. There is a disenchantment with the practice of arranged marriages, preferring pre-marital mixing of the sexes, dating and mate selection. The appeal of skimpy clothes, calypso dancing, pre-marital and extra-marital sexual affairs are also noteworthy. Respondents, while regarding themselves as less religious than their parents, see themselves as definitely more religious than their children, an obvious decline over generations. The cross-tabulations indicate that while the immigrants from Trinidad tended over time to modify their religious tradition and practices, their Canadian-born children (i.e., the next generation), caught between two cultures and no doubt experiencing tension between minority-majority cultures as they live in the culture of their parents at home but experience a different one in school, the neighbourhood and through the media, were influenced further by the dominant culture in attitudes to their religion and related issues and practices. Further, among the Trinidad Muslim respondents in Canada, the overall watering down in Islamic traditions and practices seems more prevalent among those respondents who are university educated, are professionals, and have high salaries, as anticipated by the tested hypotheses which are thereby confirmed. It is noteworthy, too, that by the second generation born in Canada, there is a swing-back (reversion) to enhanced involvement in their religion; and while interesting in itself, it seems to suggest a hope of rescuing and developing their ethnic identity and religiosity. (Abstract shortened by UMI.)
Corrigendum: Risk of SARS-CoV-2 infection among people living with HIV in Wuhan, China (Front Public Health., (2022), 10, (833783), (10.3389/fpubh.2022.833783))
Creators: name: Zhang X
name: Tang W
name: Liang K
name: Ming F
name: Wu S
name: Guo W
name: Marley G
name: Wu M
name: Liu Y
Publisher: name: Frontiers Media SA
Year: 2024

description: In the published article “Risk of SARS-CoV-2 Infection Among People Living With HIV in Wuhan, China,” there was an error in affiliation #8, Instead of “Guangdong Second Provincial Central Hospital, Southern Medical University, Guangzhou, China,” it should be “Guangdong Second Provincial General Hospital, Guangzhou, China.” The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
User-elicited dual-hand interactions for manipulating 3D objects in virtual reality environments
Creators: name: Nanjappan, Vijayakumar
name: Liang, Hai-Ning
name: Lu, Feiyu
name: Papangelis, Konstantinos
name: Yue, Yong
name: Man, Ka Lok
Publisher: name: Swinburne
Year: 2024

description: Virtual reality technologies (VR) have advanced rapidly in the last few years. Prime examples include the Oculus RIFT and HTC Vive that are both head-worn/mounted displays (HMDs). VR HMDs enable a sense of immersion and allow enhanced natural interaction experiences with 3D objects. In this research we explore suitable interactions for manipulating 3D objects when users are wearing a VR HMD. In particular, this research focuses on a user-elicitation study to identify natural interactions for 3D manipulation using dual-hand controllers, which have become the standard input devices for VR HMDs. A user elicitation study requires potential users to provide interactions that are natural and intuitive based on given scenarios. The results of our study suggest that users prefer interactions that are based on shoulder motions (e.g., shoulder abduction and shoulder horizontal abduction) and elbow flexion movements. In addition, users seem to prefer one-hand interaction, and when two hands are required they prefer interactions that do not require simultaneous hand movements, but instead interactions that allow them to alternate between their hands. Results of our study are applicable to the design of dual-hand interactions with 3D objects in a variety of virtual reality environments.
Cell Cycle Arrest and Homology Search During Double-Strand Break Repair in S. Cerevisiae
Creators: name: Zhou, Felix Y
Publisher: name: Brandeis University
Year: 2023
Subjects: DNA damage checkpoint
Double-stranded break mobility
Double-stranded break repair

description: The DNA damage response is a highly conserved and coordinated system that responds to and facilitates repair of DNA damage to maintain genomic integrity. Double-stranded breaks (DSB)s are the most deleterious form of DNA damage that, if left unrepaired, can lead to cell death or the development of cancer. When DSB is detected, the DNA damage checkpoint (DDC) arrests cells at the metaphase to anaphase barrier to allow the cells an opportunity to repair the DSB. Homologous recombination is one of the 2 branches of DSB repair and utilizes a donor with homology to the DSB-site as a template for repair. Previous work has focused on the establishment of checkpoint arrest and the repair of DSB once a donor has been found, but it is still not well understood what is required for the maintenance of checkpoint arrest or how the DSB finds a donor sequence through homology search. Using budding yeast, S. cerevisiae, I use the HO-endonuclease to make site-specific DSBs to study the requirements for the maintenance of the DNA damage checkpoint and the role of the spindle assembly checkpoint in DSB-induced checkpoint arrest. I found that most proteins required for the activation of the DNA damage checkpoint are also required for the maintenance of arrest. While the spindle assembly checkpoint is not required for the establishment of arrest, it contributes later to extend the length of arrest or is able to fully take over arrest from the DNA damage checkpoint. In addition, I found that the actin nucleator Arp2/3, which was recently found to be involved in DSB mobility in Drosophila and in human tissue culture samples, has an evolutionarily conserved role in the mobility of DSBs. Arp2/3 and the nucleation promoting factors (Las17, Vrp1, and the type-I myosins Myo3 and Myo5) are required for the initiation of long-range resection as well as increasing chromatin mobility on the local level near the DSB and globally on undamaged chromosomes. I also show that chromatin remodelers and endonucleases that affect the rate of resection have an impact on DSB mobility. Collectively, these results show the complexity of the DNA damage response and homology search.
Fibrin glue repair leads to enhanced axonal elongation during early peripheral nerve regeneration in an in vivo mouse model
Creators: name: Koulaxouzidis, Georgios
name: Reim, Gernot
name: Witzel, Christian
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2015
Subjects: subject: nerve regeneration
subject: fibrin glue
subject: peripheral nerve regeneration
subject: thy-1-YFP mice
subject: sciatic nerve
subject: branching
subject: arborisation
subject: neural regeneration
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::617 Chirurgie und verwandte medizinische Einrichtungen

description: Microsurgical suturing is the gold standard of nerve coaptation. Although literature on the usefulness of fibrin glue as an alternative is becoming increasingly available, it remains contradictory. Furthermore, no data exist on how both repair methods might influence the morphological aspects (arborization; branching) of early peripheral nerve regeneration. We used the sciatic nerve transplantation model in thy-1 yellow fluorescent protein mice (YFP; n = 10). Pieces of nerve (1cm) were grafted from YFP-negative mice (n = 10) into those expressing YFP. We performed microsuture coaptations on one side and used fibrin glue for repair on the contralateral side. Seven days after grafting, the regeneration distance, the percentage of regenerating and arborizing axons, the number of branches per axon, the coaptation failure rate, the gap size at the repair site and the time needed for surgical repair were all investigated. Fibrin glue repair resulted in regenerating axons travelling further into the distal nerve. It also increased the percentage of arborizing axons. No coaptation failure was detected. Gap sizes were comparable in both groups. Fibrin glue significantly reduced surgical repair time. The increase in regeneration distance, even after the short period of time, is in line with the results of others that showed faster axonal regeneration after fibrin glue repair. The increase in arborizing axons could be another explanation for better functional and electrophysiological results after fibrin glue repair. Fibrin glue nerve coaptation seems to be a promising alternative to microsuture repair.
Unifying ecosystem concepts and mercury biomagnification in an estuarine environment using stable isotopes (delta-carbon-13 and delta nitrogen-15).
Creators: name: Pastershank, Georgine M.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2001
Subjects: subject: Biology, Ecology.

description: Isotope ratios of carbon (13C/12C) and nitrogen (15N/14N), on a parts per thousand (‰) basis relative to a standard, were used to trace carbon flows (delta 13C) and trophic positions of organisms (delta15N). Values of delta13C and delta15N were obtained for sediments, suspended particulate matter (SPM), plants, and animals found in the Miramichi River Estuary (New Brunswick, Canada) and used to show the relationship between food web structure and patterns of mercury biomagnification. On a delta13C and delta15N basis, three different sources of energy were identified: terrestrial carbon, in situ estuarine primary production, and marine phytoplankton. Isotopically depleted delta13C and delta15N values verified terrestrial carbon was a major source of energy to estuarine sediments and SPM. A cluster analysis of mean delta13C and delta 15N values for 47 abiotic and biotic groups in this study helped to structure the community of plants and animals. Eight distinct clusters were formed: (1) estuarine sediment, and estuarine and freshwater SPM; (2) estuarine and marine primary producers; (3) freshwater fish and submerged terrestrial leaf litter, and estuarine oysters; (4) estuarine filter-feeding invertebrates; (5) estuarine deposit-feeding invertebrates; (6) estuarine planktivorous and benthivorous fish, some benthic invertebrates, and two filter-feeding marine fish; (7) estuarine carnivorous and two benthivorous fish; and (8) double crested cormorant eggs (whites and yolks). The results of this analysis show that for this coastal ecosystem, no distinction can be made in delta13C and delta15N values between estuarine and marine primary producers and filter-feeding fish, whereas freshwater fish and submerged terrestrial leaf litter were characterised by their isotopically light delta13C values. Based on measurements of delta13C and delta 15N differences between a predator and its prey, an average delta 13C- and delta15N-trophic enrichment factor (TEF) of 1.87 +/- 0.16‰ and 2.94 +/- 0.14‰, respectively, were calculated for the Miramichi River Estuary food web. Consistent with observations in other aquatic studies, a total of 4.7 delta15N-defined trophic levels were identified for the Miramichi River Estuary food web. (Abstract shortened by UMI.)
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs
Creators: name: Karlas, Alexander
name: Berre, Stefano
name: Couderc, Therese
name: Varjak, Margus
name: Braun, Peter
name: Meyer, Michael
name: Gangneux, Nicolas
name: Karo-Astover, Liis
name: Weege, Friderike
name: Raftery, Martin
name: Schoenrich, Guenther
name: Klemm, Uwe
name: Wurzlbauer, Anne
name: Bracher, Franz
name: Merits, Andres
name: Meyer, Thomas F.
name: Lecuit, Marc
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2016
Subjects: subject: Biological science
subject: Virology
subject: Medical research
subject: 500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie

description: Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome- wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication. We analyse the cellular pathways in which human proviral genes are involved and identify druggable targets. Twenty-one small- molecule inhibitors, some of which are FDA approved, targeting six proviral factors or pathways, have high antiviral activity in vitro, with low toxicity. Three identified inhibitors have prophylactic antiviral effects in mouse models of chikungunya infection. Two of them, the calmodulin inhibitor pimozide and the fatty acid synthesis inhibitor TOFA, have a therapeutic effect in vivo when combined. These results demonstrate the value of loss-of- function screening and pathway analysis for the rational identification of small molecules with therapeutic potential and pave the way for the development of new, host-directed, antiviral agents.
ENVRI-FAIR D8.2 Recommended scientific end-to-end demonstration services
Creators: name: Rivier, Leonard
name: Lund Myhre, Cathrine
name: Boulanger, Damien
name: Fiebig, Markus
name: Ferrighi, Lara
name: Tarniewicz, Jerome
name: Tjulin, Anders
Publisher: name: Zenodo
Year: 2020
Subjects: ENVRI-FAIR
deliverable
end-to-end demonstration services

description: This ENVRI-FAIR Deliverable 8.2 provides high-level requirements for two scientific end-to-end demonstration services. Beyond the IT FAIR activities of the project these demonstration services are meant to serve scientists. Their implementation will make use of the technical development of the project towards more FAIRness. End to end means from data collection to the actual production of a scientific analysis product. Demonstration is understood to mean both that the service shall need further development before a full large-scale deployment, but also that if successful in demonstrating attractiveness; they can serve as showcases for the project. This deliverable is meant for internal use within ENVRI-FAIR and more specifically in WP8 Atmosphere. The actual implementation is part of the activities of Task 8.5 that started beginning of 2020.
Warm-needling acupuncture and medicinal cake-separated moxibustion for hyperlipidemia: study protocol for a randomized controlled trial
Creators: name: Liu, Mailan
name: Zhang, Qian
name: Jiang, Shan
name: Liu, Mi
name: Zhang, Guoshan
name: Yue, Zenghui
name: Chen, Qin
name: Zhou, Jie
name: Zou, Yifan
name: Li, Dan
name: Ma, Mingzhu
name: Dai, Guobin
name: Zhong, Huan
name: Wang, Zhihong
name: Chang, Xiaorong
Publisher: name: BioMed Central
Year: 2017

description: Background: Acupuncture and moxibustion has been widely applied to hyperlipidemia treatment in clinical practice in China, serving as an alternative treatment to statins. Warm-needling acupuncture and medicinal cake-separated moxibustion have been separately reported with potential therapeutic effects on hyperlipidemia treatment in several studies but with limitations in study methodology. Combining these two modalities may provide a more advantageous strategy in treating hyperlipidemia. Therefore, a strict evaluation through well-designed randomized controlled trials (RCT) is necessary to determine their efficacy and safety on hyperlipidemia. Methods The study a multicenter, open-label, randomized, stratified, active-controlled, noninferiority trial with two parallel groups. Subjects with hyperlipidemia will be stratified into different groups by risk levels of heart diseases. They then will be instructed to the Therapeutic Lifestyle Change (TLC) diet. Those who have not reached the target lipid level will be randomly assigned to the treatments of either acupuncture and moxibustion or simvastatin with a 1:1 allocation. One hundred and thirty subjects are aimed to be recruited. The duration of intervention for this study will be 12 weeks, followed by another 4 weeks for post-treatment assessment. The primary outcome is percentage change from baseline to the end of the study in low-density lipoprotein cholesterol (LDL-C). Other indicators in lipid change, safety and adherence will also be assessed secondarily. The repeated measures, linear mixed-effects model will be applied to the analysis. Discussion Acupuncture and moxibustion could be a potentially effective treatment alternative for hyperlipidemia. A study with careful design is developed to evaluate the efficacy and safety of combined acupuncture and moxibustion, by integrating the traditional Chinese Medicine (TCM) regimens with the standardized Western medicine appraisal approach. Trial registration ClinicalTrials.gov, NCT02269046 . Registered on 26 September 2014.
Measuring eccentricity in binary black hole inspirals with gravitational waves
Creators: name: Lower, Marcus E.
name: Thrane, Eric
name: Lasky, Paul D.
name: Smith, Rory
Publisher: name: Swinburne
Year: 2024

description: When binary black holes form in the field, it is expected that their orbits typically circularize before coalescence. In galactic nuclei and globular clusters, binary black holes can form dynamically. Recent results suggest that ≈5% of mergers in globular clusters result from three-body interactions. These three-body interactions are expected to induce significant orbital eccentricity 0.1 when they enter the Advanced LIGO and Virgo band at a gravitational-wave frequency of 10 Hz. Measurements of binary black hole eccentricity therefore provide a means for determining whether or not dynamic formation is the primary channel for producing binary black hole mergers. We present a framework for performing Bayesian parameter estimation on gravitational-wave observations of eccentric black hole inspirals. Using this framework, and employing the nonspinning, inspiral-only EccentricFD waveform approximant, we determine the minimum detectable eccentricity for an event with masses and distance similar to GW150914. At design sensitivity, we find that the current generation of advanced observatories will be sensitive to orbital eccentricities of 0.05 at a gravitational-wave frequency of 10 Hz, demonstrating that existing detectors can use eccentricity to distinguish between circular field binaries and globular cluster triples. We compare this result to eccentricity distributions predicted to result from three black hole binary formation channels, showing that measurements of eccentricity could be used to infer the population properties of binary black holes.
The impact of p-T profile on exoplanet transmission spectroscopy
Creators: name: Šipková, Ema
name: Schleich, Simon
name: Boro Saikia, Sudeshna
Publisher: name: Zenodo
Year: 2025

description: The launch of the James Webb Space Telescope offers unprecedented spectroscopic data, providingan opportunity to advance our understanding of exoplanet atmospheric characterization.Analyzing the chemical composition of these atmospheres is crucial for identifying potentiallyhabitable environments and deepening our insights into planetary formation processes. ThisErasmus project focuses on investigating simulated model spectra and their dependence on differentpressure-temperature profiles, utilizing the open-source atmospheric modeling frameworkTauREx.

Here are the input parameters files used for the creation of the models described in the report from this Erasmus+ project conducted at the University of Vienna.
Virtual Social Interaction and Mental Health During COVID-19
Creators: name: Rosa, Sarah Marie
Publisher: name: Brandeis University
Year: 2021
Subjects: Social Interaction
Internalizing Symptoms
Virtual Social Interaction
COVID-19
College Students

description: The COVID-19 pandemic is a highly stressful and unprecedented event, and its effects on mental health are relatively unknown. In-person social support and interaction are known protective factors against internalizing symptoms, however, due to social distancing regulations, people are engaging in face-to-face (FTF) interactions less and technology-mediated communication (TMC) more. The current study investigated if FTF interaction and different forms of TMC relate to internalizing symptoms. Undergraduate students from Brandeis University reported their frequency of FTF interactions, and interactions through video chats, phone calls, text messaging, and social media with family, friends, and special persons, as well as their symptoms of depression and anxiety. We used multiple regression analyses to analyze the data. Overall social interaction with family and friends were significantly associated with lower internalizing symptoms overall, and depression symptoms when testing anxiety and depression separately . FTF interaction with family was negatively related to internalizing symptoms, while no forms of TMC were associated with internalizing symptoms. This suggests that social interaction, and specifically FTF interaction, may be protective against internalizing symptoms during the COVID-19 pandemic, however, TMC may not sufficiently protect against internalizing symptoms.
The Mechanisms of DNA Double Strand Break Repair and Mismatch Recognition
Creators: name: Gallagher, Danielle Nicole
Publisher: name: Brandeis University
Year: 2021
Subjects: CRISPR
gene editing
MMR
msh2
SSTR
DNA Repair

description: DNA double-strand breaks (DSBs) are among the most toxic forms of DNA damage and pose a severe threat to genomic integrity. As such, the cell has evolved highly coordinated and complex mechanisms to repair such lesions. Improper repair of DSBs can lead to chromosomal duplication, chromosomal deletions, and chromosomal translocations, all of which are hallmarks of human cancers. Previous work in DNA damage has focused on the mechanistic characterization of how cells repair DNA DSBs, and my research builds on this foundation. In this work, I study repair of DNA DSBs made with the site-specific nucleases HO and CRISPR/Cas9 to show repair via single-stranded DNA, a common method of gene editing, utilizes an uncharacterized Rad51-independent DNA repair pathway that is dependent on Rad52, Srs2, and the MRX complex, but independent of other canonical repair proteins. We also find that Rad59 plays a significant role in the process by alleviating Rad51’s inhibition of Rad52 via the Rad51 homologs. Furthermore, genome-wide genetic screening suggests that this pathway also utilizes proteins that are traditionally components of nucleotide excision repair and telomere recombination. Additionally, I investigate the effect of heterologous templates during the more conventional DSB repair pathway, gene conversion. Here, we show that there is an inherent asymmetry in DSB repair, as correction of mismatches templated upstream of the DSB are mechanistically different than those templated downstream of the DSB. While the activity of polymerase ? is primarily responsible for incorporating mismatches into the recipient locus on the left side of the DSB, mismatches templated on the right side of the DSB are primarily corrected via components of the mismatch repair pathway (MMR). These corrections patterns, however, are heavily influenced by the nature of the DSB itself. Collectively, these results highlight the immense complexity of DNA DSB repair and offer insights into the mechanisms of DNA repair, as well as to the field of genome engineering.
Adaptive signal processing in subbands using sigma-delta modulation technique.
Creators: name: Lin, Lu.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Engineering, Electronics and Electrical.

description: In this thesis, the use of subbanding and sigma-delta modulation in interference/noise cancellation is intensively studied and a sigma-delta modulated subbanded adaptive interference/noise cancellation system is proposed. The filter bank is fully sigma-delta modulated. The output signal from the filter bank is then used to produce the input to the adaptive filter. The adaptive filter is partially sigma-delta modulated. The output is demodulated at the final stage. Maintaining the sigma-delta modulated signal representation throughout the system results in considerable savings in complexity. The performance of the proposed system is studied and compared to the regular non sigma-delta modulated case regarding complexity, convergence speed and steady state error. The effect of the oversampling rate used in the sigma-delta modulation as well as the quality of the demodulator is also considered. It is shown that in the case of interference cancellation a comb filter is sufficient, while in the case of noise canceller a good quality demodulator is essential. The thesis concludes by highlighting the tradeoffs between the hardware complexity reduction and the overall system performance.
A Pedagogical Guide to Select Works by Violet Archer, Jean Coulthard and Barbara Pentland
Creators: name: Terrill, Leah Mae
Publisher: name: Washington State University
Year: 2022
Subjects: women composers
Music Composition

description: In interest of exposing intermediate students to contemporary music and drawing attention to female composers who wrote for intermediate to early advanced students, this paper is intended as an introduction and pedagogical guide for specific works in order to encourage teachers to assign these works to their students. This study will focus specifically on pedagogical pieces of three female Canadian composers: Violet Archer, Jean Coulthard, and Barbara Pentland, who were among Canada’s most influential composers in the twentieth century
An NMR study of the aggregation and alkylation reactions of some lithiated imines.
Creators: name: Carson, Philip A.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1990
Subjects: subject: Chemistry, Physical.

description: The solution structure of lithiated N-iso-propylacetaldimine, 1, was determined by a variety of NMR methods. $\sp $N-$\sp6$Li Doubly labelled samples of 1 allowed the determination of lithum-nitrogen connectivities on the basis of $\sp $N-$\sp6$Li NMR coupling patterns. The lithiated imine was found to exist as a rapidly exchanging mixture of two isomeric dimers and a triple ion, whose relative proportions were sensitive to THF concentration, and which exhibited discrete $\sp $C and $\sp $N NMR signals at $-$90$\sp\circ$C. The NMR signals for each of these nuclei were found to coalesce at higher temperatures. Under conditions of increasing THF concentration the triple ion was favoured. Addition of HMPA or PMDETA resulted in solutions containing only triple ions and monomers, but no dimers. The triple ion was found to be solvated by only one more molecule of THF than was the dimer, and HMPA and PMDETA were demonstrated to have the effect of displacing THF from coordination to the lithiated imine. The choice of solvent, and by inference, the nature of the dominant solution structures, was found not to alter the predominant selectivity for alkylation to yield $>$90% syn products. A structurally similar compound, lithiated N-iso-propylpropionaldimine, 3, was found to exhibit coalescence behaviour in the $\sp $C spectrum similar to that observed for 1. Upon addition of HMPA, however, an apparently new species was observed. $\sp1$H NMR evidence suggested that this new species had anti stereochemistry. Alkylation of solutions of 3 containing HMPA were found to give anti products in the same proportion as the new species introduced upon addition of HMPA, while in the absence of HMPA there was 93% syn selectivity.
The effect of omega-3 fatty acids on central nervous system remyelination in fat-1 mice
Creators: name: Siegert, Elise
name: Paul, Friedemann
name: Rothe, Michael
name: Weylandt, Karsten H.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: Multiple sclerosis
subject: n-3 PUFAs
subject: Lipid mediators
subject: Inflammation
subject: Oligodendrocytes
subject: Remyelination
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: Background There is a large body of experimental evidence suggesting that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) are capable of modulating immune function. Some studies have shown that these PUFAs might have a beneficial effect in patients suffering form multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous system (CNS). This could be due to increased n-3 PUFA-derived anti-inflammatory lipid mediators. In the present study we tested the effect of an endogenously increased n-3 PUFA status on cuprizone-induced CNS demyelination and remyelination in fat-1 mice versus their wild-type (wt) littermates. Fat-1 mice express an n-3 desaturase, which allows them to convert n-6 PUFAs into n-3 PUFAs. Results CNS lipid profiles in fat-1 mice showed a significant increase of eicosapentaenoic acid (EPA) levels but similar docosahexaenoic acid levels compared to wt littermates. This was also reflected in significantly higher levels of monohydroxy EPA metabolites such as 18-hydroxyeicosapentaenoic acid (18-HEPE) in fat-1 brain tissue. Feeding fat-1 mice and wt littermates 0.2% cuprizone for 5 weeks caused a similar degree of CNS demyelination in both groups; remyelination was increased in the fat-1 group after a recovery period of 2 weeks. However, at p = 0.07 this difference missed statistical significance. Conclusions These results indicate that n-3 PUFAs might have a role in promotion of remyelination after toxic injury to CNS oligodendrocytes. This might occur either via modulation of the immune system or via a direct effect on oligodendrocytes or neurons through EPA- derived lipid metabolites such as 18-HEPE.
COVID-19 and Female Genital Mutilation/Cutting and child marriage: An online multi-country cross sectional survey
Creators: name: Kingoo, James Munyao
name: Temmerman, Marleen
name: Esho, Tammary
name: Tucker, Joseph D.
name: Abdelhamed, Amr
name: Kimani, Samuel
name: Pande, Shania
name: Kpokiri, Eneyi E.
name: Velde, Sarah Van de
name: Shamu, Simukai
name: Omwoha, Joyce
Publisher: name: Public Library of Science
Year: 2024

description: Female Genital Mutilation/Cutting (FGM/C) and child marriage are prevalent in many countries in Asia and Africa. These practices are a violation of human rights and have significant impacts on the physical and mental well-being of those affected. COVID-19 restrictions such as lockdowns and closure of schools may have influenced the occurrence of FGM/C and child marriage. This analysis reported on the impact of these restrictions on FGM/C and child marriage. The International Sexual Health And REproductive Health (I-SHARE) research team organised a multi-country online survey. Sampling methods included convenience samples, online panels, and population-representative samples. Data collected included the impact of COVID-19 restrictions on the occurrence, intention to practice and change in plans to organise FGM/C and child marriage. Data were analysed from 14 countries that reported on FGM/C and child marriage using basic descriptive statistics. Given it was an online survey, we had more responses from urban areas. Among the 22,724 overall participants, 8,829 participants (38.9%) responded to the survey items on FGM/C and child marriage and were included in this analysis. 249 (3.4%) participants stated that FGM/C occurred in their community during COVID-19. Out of this, COVID-19 affected the plans of 26 (20%) participants intending to organise circumcision and 15% of participants planned to organise FGM/C earlier. People with a worry about finances during COVID-19 were more likely to have an earlier plan to organise FGM/C during COVID-19. In total, 1,429 (13%) participants reported that child marriage occurred in their community. The pandemic affected plans of 52 (13%) participants intending to arrange child marriage and 7.7% (29/384) participants expressed intent to arrange the marriage sooner than planned. People with financial insecurities during COVID-19 were more likely to arrange a child marriage earlier. Thus, our study found that the pandemic impacted plans related to FGM/C and child marriage practices, resulting in many carrying out the practices sooner or later than initially planned.
Non-linear analysis of visual evoked potentials: applications for understanding the role of the afferent streams in visual processing
Creators: name: Hugrass, Laila Elaine
Publisher: name: Swinburne
Year: 2024

description: Several different pathways transmit information from the retina to the brain. One major pathway prefers slow, yet detailed input, and the other major pathway prefers fast, yet coarse input. This research used non-invasive techniques to study electrophysiological signals from the brain. Responses arising from the two major visual pathways were studies separately, based on their different temporal sensitivities. The findings highlight the importance of using complementary techniques to investigate the early stages of visual processing.
Representations of Aging in Modern Hebrew Literature: Bodies, Subjects, Nation
Creators: name: Feingold, Deborah
Publisher: name: Brandeis University
Year: 2026
Subjects: embodiment
gender
modern Hebrew literature
nation
Gender studies
Aging

description: Older protagonists in novels and stories have appeared more frequently in recent decades in modern Hebrew/Israeli literature, and yet there is a dearth of scholarly literature about this phenomenon; this dissertation will be the first full-length manuscript to explore representations of aging in this literature. I employ a multidisciplinary approach calling on a variety of academic fields including literary age studies, cultural gerontology/critical age studies, feminist, gender, queer, and sexuality studies, modern Hebrew literary studies, and Israel studies. Through close readings of Israeli prose fiction from the 1980s to the present, this project broadly aims: (1) to expose and challenge the prevalent and enduring stereotypes and misrepresentations of aging and the aging subject; (2) to recover, elucidate, and center the stories of older characters, especially those on the margins of this marginalized cohort; (3) to explore the varied permutations and (taboo) iterations of aging bodies; (4) to propose aging as a stage of the lifecycle that is unpredictable and transformative, and that is defined by renewal, and “becoming;” and (5) to recognize age/ing as a salient category from which to identify the priorities and anxieties of the nation both looking back towards its beginnings and in the present. Each chapter contains two texts that examine an issue highlighting obstacles and/or provocations facing aging subjects and presenting opportunities for their growth. These issues are: (queer) desire and sexuality (Chapter 1); performative age, or the imperative to deny aging and to remain “ageless,” and performances of youth (Chapter 2); dependency and disability in deep old age and the counternarrative of interdependence (Chapter 3); and traumatic (embodied) memory (Chapter 4).
Est-ce qu'il y a continuité dans les "demandes traditionnelles" du Québec.
Creators: name: Bertrand, Gilles.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1999
Subjects: subject: Political Science, General.

description: Dans les pourparlers précédant l'Accord du lac Meech, les demandes «traditionnelles» du Québec ont pris une place très importante dans le discours. Cette étude retrace les demandes du Québec depuis 1960 jusqu'à 1990, afin de déceler s'il s'y trouve effectivement un caractère de continuité, en comparant les revendications que le Québec soumet au gouvernement central tout au long de cette période. Les résultats démontrent que la constance n'est pas dans la formulation des demandes. La continuité se retrouverait plutôt dans la lutte politique pour la reconnaissance du Québec. Ainsi, les demandes «traditionnelles» du Québec s'inscriraient comme un enjeu de négociation et de mobilisation dans la lutte de pouvoir qui se joue entre Ottawa et Québec.
Assessing varicella vaccine effectiveness and its influencing factors using health insurance claims data, Germany, 2006 to 2015
Creators: name: Rieck, Thorsten
name: Feig, Marcel
name: Heiden, Matthias An Der
name: Siedler, Anette
name: Wichmann, Ole
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2017
Subjects: subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

description: In Germany, routine childhood varicella vaccination was implemented in 2004 with two doses recommended since 2009. We used an immunisation information system based on countrywide health insurance claims data to analyse vaccine effectiveness (VE) and factors influencing VE. We applied proportional hazard models to estimate VE under various conditions and compared the risk of acquiring varicella among unvaccinated children in regions with high vs low vaccination coverage (VC). Among 1.4 million children we identified 29,404 varicella cases over a maximum follow-up of 8 years post-vaccination. One-dose VE was 81.9% (95% confidence interval (CI): 81.4–82.5), two-dose VE 94.4% (95% CI: 94.2–94.6). With dose one given 1–27 days after measles-containing vaccine (MCV), one-dose VE was 32.2% (95% CI: 10.4–48.6), two-dose VE 92.8% (95% CI: 84.8–96.6). VE was not associated with age at vaccination (11–14 vs ≥ 15 months), time since vaccination, or vaccine type. Unvaccinated children had a twofold higher risk of acquiring varicella in low VC regions. Our system generated valuable data, showing that two-dose varicella vaccination provides good protection for at least 8 years. Unvaccinated children benefit from herd effects. When the first varicella vaccine dose is given shortly after MCV, a second dose is essential.