The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria
Creators: name: Zuberbier, Torsten
name: Abdul Latiff, Amir Hamzah
name: Abuzakouk, Mohamed
name: Aquilina, Susan
name: Asero, Riccardo
name: Baker, Diane
name: Ballmer‐Weber, Barbara
name: Bangert, Christine
name: Ben‐Shoshan, Moshe
name: Bernstein, Jonathan A.
name: Bindslev‐Jensen, Carsten
name: Brockow, Knut
name: Brzoza, Zenon
name: Chong Neto, Herberto Jose
name: Church, Martin K.
name: Criado, Paulo R.
name: Danilycheva, Inna V.
name: Dressler, Corinna
name: Ensina, Luis Felipe
name: Fonacier, Luz
name: Gaskins, Matthew
name: Gáspár, Krisztian
name: Gelincik, Aslı
name: Giménez‐Arnau, Ana
name: Godse, Kiran
name: Gonçalo, Margarida
name: Grattan, Clive
name: Grosber, Martine
name: Hamelmann, Eckard
name: Hébert, Jacques
name: Hide, Michihiro
name: Kaplan, Allen
name: Kapp, Alexander
name: Kessel, Aharon
name: Kocatürk, Emek
name: Kulthanan, Kanokvalai
name: Larenas‐Linnemann, Désirée
name: Lauerma, Antti
name: Leslie, Tabi A.
name: Magerl, Markus
name: Makris, Michael
name: Meshkova, Raisa Y.
name: Metz, Martin
name: Micallef, Daniel
name: Mortz, Charlotte G.
name: Nast, Alexander
name: Oude‐Elberink, Hanneke
name: Pawankar, Ruby
name: Pigatto, Paolo D.
name: Ratti Sisa, Hector
name: Rojo Gutiérrez, María Isabel
name: Saini, Sarbjit S.
name: Schmid‐Grendelmeier, Peter
name: Sekerel, Bulent E.
name: Siebenhaar, Frank
name: Siiskonen, Hanna
name: Soria, Angele
name: Staubach‐Renz, Petra
name: Stingeni, Luca
name: Sussman, Gordon
name: Szegedi, Andrea
name: Thomsen, Simon Francis
name: Vadasz, Zahava
name: Vestergaard, Christian
name: Wedi, Bettina
name: Zhao, Zuotao
name: Maurer, Marcus
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: angioedema
subject: consensus
subject: evidence-based
subject: hives
subject: itch
subject: mast cell
subject: urticaria
subject: wheal
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA(2)LEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF; EuroGuiDerm), and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology with the participation of 64 delegates of 50 national and international societies and from 31 countries. The consensus conference was held on 3 December 2020. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). Urticaria is a frequent, mast cell-driven disease that presents with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic spontaneous or inducible urticaria is disabling, impairs quality of life, and affects performance at work and school. This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria.