cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Investigating Phenolic-Mediated Protein Matrix Development for Potential Control of Cereal Starch Digestion
Creators: name: R. Schmidt, Leigh C
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Food chemistry and food sensory science
Food sciences not elsewhere classified

description: Shifts in the human diet to more refined foods and ingredients have contributed to the rise in metabolic disease rates associated with long-term consumption of foods causing swift rises in blood glucose response. Foods which result in a more moderate blood glucose curve are considered healthier by increasing satiety and reducing oxidative stress. Sorghum products contain naturally slowly digested starch. The matrix of sorghum porridges contains kafirin protein bodies which cross link around gelatinizing starch molecules, while similar nascent matrices in other cereals aggregate and collapse. The 3-deoxyanthocyanidin pigments unique to sorghum may be accountable for the difference in matrix stability. The density of the starch entrapped in the matrices is thought to partially inhibit α-amylase access to the starch, reducing overall starch digestion and thereby mitigating glucose response. The purpose of this work was to increase our understanding of how phenolic compounds in sorghum interact with endosperm proteins to create a stable matrix, and to explore if the knowledge might be translated to other starchy cereal products. In the first study, phenolic extracts from flours (sorghum, corn masa, white rice) were characterized for phenolic content, antioxidant activity, phenolic components, and their ability to interact with a model protein system (ovalbumin) in order to examine protein polymerization. In the second study, specific phenolic compounds in sorghums (p-coumaric, sinapic, and gallic acids; (+)-catechin; and apigeninidin, a 3-deoxyanthocyanidin found in sorghums) were interacted in the model protein system at different concentrations to observe extent and type of protein polymerization, and promising compounds subjected to fluorescence quenching spectroscopy to examine the nature of the interactions. The final study explored the effects of apigeninidin addition to a yellow corn flour and naturally present anthocyanin (blue corn) on starch digestion and microstructure of porridges by utilizing an in vitro α-amylase assay and confocal microscopy. The slow digestion of starch in cooked sorghum products can be attributed to the 3-deoxyanthocyanidin compounds present in the grain participating in sulfhydryl-disulfide interchanges which results in extensive kafirin cross-linking surrounding starch granules. While other phenolic and redox-active components may affect matrix formation and stability, 3-deoxyanthocyanidins appear to have the most direct influence, and their ability to modify food protein matrices appears to have a direct result on starch digestion in vitro.
Review of Performing the Socialist State by Xiaomei Chen, in CLEAR: Chinese Literature: Essays, Articles, Reviews 45 (2023): 338-340
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Theater
subject: Censorship
subject: Propaganda
subject: World politics

description: In this review, Alexa Alice Joubin outlines the main argument of Xiaomei Chen's Performing the Socialist State: Modern Chinese Theater and Film Culture. "The eight chronologically- and thematically-organized chapters in this book provide a much-needed critical survey of spoken drama (huaju) from its inception through the Republican and Maoist eras to the first decade of the twenty-first century. Spoken drama, as Chen’s diachronic study shows, has evolved across an astonishing range of media in the forms of women’s theatre, socialist theatre, “red classic” films, and even in the “sonic theatre” of the Internationale, the unofficial anthem of various communist and socialist movements." "The book stakes two important claims. First, the book demonstrates that several political and aesthetic elements inform the development of modern theatre in various periods that have previously been regarded as siloed and distinct, including the Republican, socialist, and postsocialist eras. Secondly, the book argues that, contrary to common wisdom, state regulation and censorship affect, but do not stifle, artistic imagination."
Additional file 2 of Cortical superficial siderosis is associated with reactive astrogliosis in cerebral amyloid angiopathy
Creators: name: Auger, Corinne A.
name: Perosa, Valentina
name: Greenberg, Steven M.
name: van Veluw, Susanne J.
name: Kozberg, Mariel G.
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Cell Biology
subject: Neuroscience
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences

description: Additional file 2: Figure S2. GFAP-positive and CD68-positive cell density vs. iron density in the outer and inner portions of the cortex. Examples of adjacent sections from the frontal lobe stained (A) for iron with Perls’ Prussian blue and for (B) GFAP and (C) CD68 via immunohistochemistry. (D, E, F) Heat maps consisting of only the outermost 1000 µm of the cortex, in 250 µm * 250 µm pixels, on the same slides. (H, I) Plots of inflammatory cell density vs. iron deposit density in the outermost 1000 µm of the cortex. Each dot represents one brain, and the inflammatory cell density for a brain in one iron category is the mean of the inflammatory cell densities for all pixels in that section that fall within that category. Each brain may appear in each column. Skillings-Mack test, n = 19 cases. Post-hoc pairwise comparisons were performed using Conover tests with Benjamini-Hochberg p-value adjustment. (H) In the outer edge of the cortex, mean GFAP-positive cell densities were higher in pixels with higher iron burden in four predefined categories. None of the pairwise comparisons were significant. (I) Mean CD68-positive cell densities were not significantly higher in pixels with higher iron burden. (J, K, L) Heat maps of the cortex without the outermost 1000 µm, in 500 µm * 500 µm pixels, on the same slides. (M, N) Plots of inflammatory cell density vs. iron deposit density in the cortex without the outermost 1000 µm. *p < 0.05. (M) In the cortex without the outer edge, mean GFAP-positive cell densities were higher in pixels with higher iron burden in four predefined categories. (N) In the cortex without the outer edge, mean CD68-positive cell densities were not significantly higher in pixels with higher iron burden.
Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology
Creators: name: Jin, Mei
name: Ma, Lingxiang
name: Li, Bing
name: Huang, Xuning
name: Chen, Meihua
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Cell Biology
subject: Physiology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Science Policy

description: Cardiovascular complications remain a leading cause of mortality in patients with end-stage kidney disease undergoing dialysis. This study aimed to evaluate differences in left atrial (LA) structure and function between hemodialysis and peritoneal dialysis patients using four-dimensional automatic left atrial quantification (4D Auto LAQ) technology. This study included 125 patients with end-stage kidney disease, categorized into hemodialysis (n = 69) and peritoneal dialysis (n = 56) groups. Conventional echocardiography and 4D Auto LAQ were used to assess LA volume and strain parameters. Differences between groups were analyzed. Hemodialysis patients exhibited significantly larger LA minimum volume, maximum volume, pre-atrial contraction volume, and maximum volume index compared to peritoneal dialysis patients (p < 0.05). Conversely, hemodialysis patients had significantly lower LA reservoir circumferential strain (LASr-c) and conduit circumferential strain (LAScd-c) than peritoneal dialysis patients (p < 0.05). LA ejection fraction (LAEF) correlated positively with LASr-c (r = 0.809). Multivariate regression analysis identified LASr-c as independently associated with dialysis modality and LAEF. Sensitivity analysis confirmed LAEF as an independent determinant of LASr-c. Hemodialysis is associated with increased LA volume and impaired LA function compared to peritoneal dialysis. These findings highlight the importance of LA monitoring in dialysis patients to identify early cardiac dysfunction.
Additional file 1 of Cross-reactive CD8+ T cell responses to tumor-associated antigens (TAAs) and homologous microbiota-derived antigens (MoAs)
Creators: name: Cavalluzzo, Beatrice
name: Viuff, Marie Christine
name: Tvingsholm, Siri Amanda
name: Ragone, Concetta
name: Manolio, Carmen
name: Mauriello, Angela
name: Buonaguro, Franco M.
name: Tornesello, Maria Lina
name: Izzo, Francesco
name: Morabito, Alessandro
name: Hadrup, Sine Reker
name: Tagliamonte, Maria
name: Buonaguro, Luigi
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Suppl. Fig. S1. Descriptive flow cytometry plots for gating strategy on healthy donors and cancer patients’ PBMCs stained with DNA-barcoded pMHC multimers and surface antibody markers to sort viral/microbiome-derived (APC) and TAA/double positive (PE/PE+APC) multimer+ CD8+ T cells and to quantify multimer+ CD8+ T cells. Suppl. Figs. S2-15. Predicted 3D conformations of TAA and microbiota-derived paired peptides. The surface conformation of the paired TAA MoA-derived peptides is shown. Residues in the Mo epitopes that differed from the TAA sequences are indicated in red. A-Red areas  = contact points with HLA-A molecule; blue areas = contact points with TCR α chain; Light Blue  areas = contact points with TCR β chain. The images below the peptides show contact sites with the TCR (yellow areas). Suppl. Fig. S16. Diagrams show the total number of significant responses in DNA-barcoded pMHC multimers for HS (A) and CP (B).
Laser Sintering of Nanocomposite on Flexible Substrate: Experimental Study and Molecular Dynamics Simulation
Creators: name: Kang, Zheng
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Mechanical engineering not elsewhere classified

description: Flexible electronics involve electronic circuits fabricated on flexible substrates. They have promising applications in wearable devices and flexible sensors etc. and have thus attracted much research interest in recent years. The working environment of flexible electronic devices may require them to go through repeating deformations, during which cracks may generate and grow in the metallic components of the devices, reducing service life of these devices. To address such challenges, it is desirable to investigate methods to improve the reliability of flexible electronics in these working conditions. This research reported here will focus on topics related to laser-based fabrication of carbon nanotube-metal composites on flexible substrates: Experimental studies were carried out to investigate the structures and properties of carbon nanotube – metal composites produced by a laser-based fabrication process on flexible substrates. Extensive characterizations and testes were carried out, including measurements of electrical resistivity of laser-sintered material, characterizations with SEM, TEM, EDS and XPS, and mechanical performance tests (bending fatigue test, static tensile test and adhesion test). The experimental study suggests that the laser-fabricated metal composites have promising potentials to help enhancing reliability and durability of metal components in flexible electronic devices. A molecular dynamics model was also developed to study the coalescence of metal nanoparticles (gold NPs in this study) around the end of a multi-walled carbon nanotube (MWCNT) and their interaction with the CNT at elevated temperatures. The MD model was first tested by comparing the MD-predicted NP melting points with experiment-deduced results from the literature. Then the coalescence of five 3-nm Au NPs around the end of a MWCNT and their interactions with the CNT were studied with MD simulations. The molecular system was studied under different elevated temperatures and for different carbon nanotube diameters, and the simulation results were analyzed and discussed.
Identifying core symptom clusters based on symptom distress levels in patients with maintenance hemodialysis: a cross-sectional network analysis
Creators: name: Chang, Yaxin
name: Wang, Ke
name: Liu, Mengjia
name: Zhang, Zhifang
name: Ma, Huiwen
name: Gao, Xinping
name: Yang, Zhaoxia
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Ecology
subject: Sociology
subject: FOS: Sociology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Science Policy
subject: Hematology
subject: Plant Biology

description: To explore the symptom clusters of patients undergoing maintenance hemodialysis and construct a symptom network to identify the core symptoms and core symptom clusters, to provide reference for precise symptom management. Conveniently selected 354 patients with maintenance hemodialysis were surveyed cross-sectionally using the general information questionnaire, the Dialysis Symptom Index and the Kidney Disease Questionnaire. Symptom clusters were extracted using exploratory factor analysis, and core symptom clusters were identified using hierarchical regression and network analysis. The most common and severe symptoms were fatigue, dry skin and itching, and the most distressing symptoms were fatigue, itching and trouble falling asleep. Within the symptom network, worry (rs = 1.0) had the highest strength, trouble staying asleep(rc = 0.01) had the highest closeness, and fatigue had the highest betweenness (rb = 30) and bridge strength (rbs = 0.53). A total of four symptom clusters were extracted, namely psychological symptom cluster, sleep disorder symptom cluster, uremia-related symptom cluster, and neurological symptom cluster. Hierarchical regression results showed that the psychological symptom cluster had the greatest impact on patients’ quality of life. Fatigue was the most severe symptom and the bridge symptom, the uremia-related symptom cluster caused the greatest distress for patients, worry was the core symptom, and the psychological symptom cluster was identified as the core cluster. Clinical staff can provide effective symptom management and improve patient symptom burden by establishing intervention strategies centered on these results.
Additional file 3 of Artificial intelligence learning landscape of triple-negative breast cancer uncovers new opportunities for enhancing outcomes and immunotherapy responses
Creators: name: Li, Shuyu
name: Zhang, Nan
name: Zhang, Hao
name: Zhou, Ran
name: Li, Zirui
name: Yang, Xue
name: Wu, Wantao
name: Li, Hanning
name: Luo, Peng
name: Wang, Zeyu
name: Dai, Ziyu
name: Liang, Xisong
name: Wen, Jie
name: Zhang, Xun
name: Zhang, Bo
name: Cheng, Quan
name: Zhang, Qi
name: Yang, Zhifang
Publisher: name: figshare
Year: 2024
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Supplementary Material 3
Review of Rethinking Chinese Socialist Theaters of Reform, in CLEAR: Chinese Literature: Essays, Articles, Reviews 45 (2023): 335-338
Creators: name: Joubin, Alexa Alice
Publisher: name: Humanities Commons
Year: 2023
Subjects: subject: Theater
subject: Feature films
subject: China
subject: Censorship
subject: Propaganda
subject: Dance
subject: Musicals

description: Going against the grain, this collection counters the common perception of the Maoist era as a time of ideological conformity. The contributors persuasively demonstrate that theatre activities were varied and lively between the 1950s and 1970s. While there was state control over the arts, performances in urban spaces were more frequently censored than those in the countryside. This admirable collection of an Introduction, nine chapters, and Xiaomei Chen’s “personal reflection” on her experience growing up in Maoist China which serves as the epilogue, covers a wide range of performance genres, including xiqu operas, huaju spoken drama pieces, wuju dance drama productions, and propaganda performances. Featuring research by “theater specialists, literary scholars, historians, comparatists, and cultural anthropologists,” this co-edited book is truly multidisciplinary (271).
sj-pdf-2-imr-10.1177_03000605211028026 - Supplemental material for Global prevalence of long-term neurodevelopmental impairment following extremely preterm birth: a systematic literature review
Creators: name: Sarda, Sujata P.
name: Sarri, Grammati
name: Siffel, Csaba
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 111708 Health and Community Services
subject: FOS: Health sciences
subject: Cardiology
subject: 110599 Dentistry not elsewhere classified
subject: FOS: Clinical medicine
subject: 110305 Emergency Medicine
subject: 110306 Endocrinology
subject: 110308 Geriatrics and Gerontology
subject: 110904 Neurology and Neuromuscular Diseases
subject: 111099 Nursing not elsewhere classified
subject: 111199 Nutrition and Dietetics not elsewhere classified
subject: 111299 Oncology and Carcinogenesis not elsewhere classified
subject: 110314 Orthopaedics
subject: 110604 Sports Medicine
subject: 110315 Otorhinolaryngology
subject: 111702 Aged Health Care
subject: 111403 Paediatrics
subject: 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
subject: 170199 Psychology not elsewhere classified
subject: FOS: Psychology
subject: 110319 Psychiatry (incl. Psychotherapy)
subject: 111799 Public Health and Health Services not elsewhere classified
subject: 110203 Respiratory Diseases
subject: 160807 Sociological Methodology and Research Methods
subject: FOS: Sociology
subject: 110323 Surgery

description: Supplemental material, sj-pdf-2-imr-10.1177_03000605211028026 for Global prevalence of long-term neurodevelopmental impairment following extremely preterm birth: a systematic literature review by Sujata P. Sarda, Grammati Sarri and Csaba Siffel in Journal of International Medical Research
Examining Classroom Quality As A Moderator Between Pre-Kindergarten Participation and School Readiness
Creators: name: Budrevich, Adassa
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Early childhood education

description: The current study examined the extent to which associations between participation in a targeted state-funded pre-kindergarten (pre-k) program and children’s literacy, numeracy, executive function (EF), and social-emotional skills were moderated by the quality of teacher-child interactions. Data came from an evaluation of a state-funded pre-k program including children enrolled in pre-k and those in a matched comparison group. The sample consisted of 558 children (Mage = 57.74 months) from two cohorts (48.9% female; 43.7% African American; 0.8% Asian; 32.3% European American; 12.4% Hispanic; 10.4% Multiracial). Children’s school readiness assessments and teacher surveys were collected during fall and spring of the preschool year. Research assistants assessed teacher-child interactions using the Pre-K Classroom Assessment Scoring System (CLASS; Pianta, La Paro, Hamre, 2008) once in the winter of the preschool year. Two-level multilevel linear models were conducted for each school readiness domain and included a variety of control variables. Results suggested that emotional support, classroom organization, and instructional support did not significantly moderate the relation between pre-k participation and literacy, numeracy, EF, and social-emotional skills.
Role of microvascular pericyte dysfunction in antibody-mediated rejection following kidney transplantation
Creators: name: Xu, Jie
name: Pu, Junyan
name: Chen, Hao
name: Sun, Li
name: Fei, Shuang
name: Han, Zhijian
name: Tao, Jun
name: Ju, Xiaobing
name: Wang, Zijie
name: Tan, Ruoyun
name: Gu, Min
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Hematology
subject: Computational Biology

description: To investigate the role of microvascular pericyte dysfunction in antibody-mediated rejection (ABMR) of transplanted kidneys. A total of 160 patients who underwent kidney transplantation in our hospital from 2004 to 2020 were enrolled, divided into 4 groups: ABMR group (n = 79), TCMR group (n = 20), mixed rejection group (n = 25) and control group (n = 36). Postoperative renal function indicators were compared, and immunohistochemical and immunofluorescence staining was performed on graft tissues and mice models using the pericyte marker PDGFR-β. An in vitro pericyte dysfunction model was co-cultured with vascular endothelial cells for functional assessment through Western blotting, PCR, and wound healing tests. KEGG pathway analysis from the GEO database identified gene expression changes in pericytes, which were further analyzed using electron microscopy and Western blot techniques. There were statistically significant differences in creatinine, urea nitrogen, urine protein, and eGFR among the groups over time, with ABMR displaying the poorest outcomes. Immunohistochemistry revealed lower pericyte expression in ABMR, which was confirmed in mouse model studies showing reduced PDGFR-β expression in ABMR. KEGG analysis highlighted decreased autophagy in pericyte dysfunction, supported by electron microscopy and Western blot findings indicating reduced autophagy and pericyte damage, which could be reversed by chloroquine. ABMR episodes worsened the long-term prognosis of transplanted kidneys. pericyte dysfunction appears to be one of the crucial causes of poor prognosis in ABMR patients. In vitro studies demonstrated that dysfunction of microvascular pericytes can result in damage to vascular endothelial cells, with autophagy impairment being a significant mechanism contributing to pericyte dysfunction.
APPLICATIONS OF MICROHEATER/RESISTANCE TEMPERATURE DETECTOR AND ELECTRICAL/OPTICAL CHARACTERIZATION OF METALLIC NANOWIRES WITH GRAPHENE HYBRID NETWORKS
Creators: name: Back, Doosan
Publisher: name: Purdue University Graduate School
Year: 2020
Subjects: Electrical engineering not elsewhere classified
Fluid mechanics and thermal engineering not elsewhere classified
Computational methods in fluid flow, heat and mass transfer (incl. computational fluid dynamics)
Microelectronics
Microtechnology
Environmental engineering not elsewhere classified
Composite and hybrid materials

description: A microheater and resistance temperature detector (RTD) are designed and fabricated for various applications. First, a hierarchical manifold microchannel heatsink with an integrated microheater and RTDs is demonstrated. Microfluidic cooling within the embedded heat sink improves heat dissipation, with two-phase operation offering the potential for dissipation of very high heat fluxes while maintaining moderate chip temperatures. To enable multi-chip stacking and other heterogeneous packaging approaches, it is important to densely integrate all fluid flow paths into the device. Therefore, the details of heatsink layouts and fabrication processes are introduced. Characterization of two-phase cooling as well as reliability of the microheater/RTDs are discussed. In addition, another application of microheater for mining particle detection using interdigitated capacitive sensor. While current personal monitoring devices are optimized for monitoring microscale particles, a higher resolution technique is required to detect sub-micron and nanoscale particulate matters (PM) due to smaller volume and mass of the particles. The detection capability of the capacitive sensor for sub-micron and nanoparticles are presented, and an incorporated microheater improved stable capacitive sensor reading under air flow and various humidity. This paper also introduces the characterization of nanomaterials such as metallic nanowires (NWs) and single layer graphene. First, the copper nanowire (CuNW)/graphene hybrid networks for transparent conductors (TC) is investigated. Though indium tin oxide (ITO) has been widely used, demands for the next generation of TC is increasing due to a limited supply of indium. Thus, the optical and electrical properties of CuNW/graphene hybrid network are compared with other transparent conductive materials including ITO. Secondly, silver nanowire (AgNW) growth technique using electrodeposition is introduced. A vertically aligned branched AgNW arrays is made using a porous anodic alumina template and the optical properties of the structure are discussed.
Influence de facteurs organisationnels du conseil d'administration sur la performance hospitalière au Mali
Creators: name: Mamady SISSOKO
name: Siaka FAROKO
name: CISSE AMINATA TRAORE
name: Yaya SIDIBE
Publisher: name: Zenodo
Year: 2025

description: Cet article traite l’influence d’organisation du conseil d’administration sur la performance des hôpitaux au Mali.  Pour arriver à cet objectif nous avons opté pour une méthode quantitative. L’échantillon a été sélectionné par la méthode non probabiliste et la technique par choix raisonné. Notre population source est composée des hôpitaux régionaux disposant d’un conseil d’administration. L’échantillon est composé de 30 hôpitaux. La collecte des données a été faite à partir d’un questionnaire adressé aux dirigeants et personnels des hôpitaux. Les données recueillies ont fait l’objet d’une analyse univariée descriptive puis d’une analyse de la régression linéaire multiple sous SPSS26. Ces deux types d’analyses ont suffis pour vérifier nos hypothèses émises. Les principaux résultats obtenus montrent que certaines variables de l’organisation du conseil d’administration influencent négativement et positivement la performance des hôpitaux au Mali. La taille du conseil d’administration influence négativement la performance des hôpitaux tandis que le taux de présence important d’administrateur indépendant dans le conseil, la présence du personnel médical et le nombre réduit de réunion dans le conseil d’administration influencent positivement la performance des hôpitaux au Mali.

Les implications théoriques des résultats se situent à ses contributions à la littérature sur l’organisation du conseil d’administration en se basant sur la théorie des parties prenantes. Concernant les contributions pratiques nos résultats aident les décideurs dans la mise en place des reformes contribuant à l’amélioration de la performance des hôpitaux.
Additional file 1 of Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial
Creators: name: Chevret, Sylvie
name: Bouadma, Lila
name: Dupuis, Claire
name: Burdet, Charles
name: Timsit, Jean-François
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Cancer
subject: Science Policy
subject: Mental Health
subject: Virology

description: Additional file 1: Table S1. Treatment effect on 60-day mortality across subsets. Figure S1. Sensitivity analyses using either Cox model with sceptical or enthusiastic priors, or beta-binomial models with noninformative priors. Figure S2. Estimated survival curves according to DXM group and time since disease onset (A), D-dimers (B) or ferritin (C) levels
sj-docx-1-srd-10.1177_23780231211031320 – Supplemental material for Secularism and Fertility Worldwide
Creators: name: Schnabel, Landon
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Sociology
subject: FOS: Sociology

description: Supplemental material, sj-docx-1-srd-10.1177_23780231211031320 for Secularism and Fertility Worldwide by Landon Schnabel in Socius
Ensuring Network Designs Meet Performance Requirements under Failures
Creators: name: Chang, Yiyang
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Digital processor architectures
Other information and computing sciences not elsewhere classified
Networking and communications

description: With the prevalence of web and cloud-based services, there is an ever growing requirement on the underlying network infrastructure to ensure that business critical traffic is continually serviced with acceptable performance. Networks must meet their performance requirements under failures. The global scale of cloud provider networks and the rapid evolution of these networks imply that failures are the norm in production networks today. Unplanned downtime can cost billions of dollars, and cause catastrophic consequences. The thesis is motivated by these challenges and aims to provide a principled solution to certifying network performance under failures. Network performance certification is complicated, due to both the variety of ways a network can fail, and the rich ways a network can respond to failures. The key contributions of this thesis are: (i) a general framework for robustly certifying the worst-case performance of a network across a given set of uncertain scenarios. A key novelty is that the framework models flexible network response enabled by recent emerging trends such as Software-Defined Networking; (ii) a toolkit which automates the key steps needed in robust certification making it suitable for use by a network architect, and which enables experimentation on a wide range of robust certification of practical interest; (iii) Slice, a general framework which efficiently classifies failure scenarios based on whether network performance is acceptable for those scenarios, and which allows reasoning about performance requirements that must be met over a given percentage of scenarios. We also show applications of our frameworks in synthesizing designs that are guaranteed to meet a performance goal over all or a desired percentage of a given set of scenarios. The thesis focuses on wide-area networks, but the approaches apply to data-center networks as well.
sj-pdf-3-pic-10.1177_09544062211017942 - Supplemental material for A mathematical model for evaluating adhesion contact of an elastomeric seal-on-seal structure
Creators: name: Liao, C-J
name: Lu, H-R
name: Sun, H-L
name: Chang, X-H
name: Dai, W
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 99999 Engineering not elsewhere classified
subject: FOS: Other engineering and technologies

description: Supplemental material, sj-pdf-3-pic-10.1177_09544062211017942 for A mathematical model for evaluating adhesion contact of an elastomeric seal-on-seal structure by C-J Liao, H-R Lu, H-L Sun, X-H Chang and W Dai in Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science
title: Technical Design Report for the LUXE experiment
Creators: name: Abramowicz, H.
name: Almanza Soto, M.
name: Altarelli, M.
name: Aßmann, R.
name: Athanassiadis, A.
name: Avoni, G.
name: Behnke, T.
name: Benettoni, M.
name: Benhammou, Y.
name: Bhatt, J.
name: Blackburn, T.
name: Blanch, C.
name: Bonaldo, S.
name: Boogert, S.
name: Borysov, O.
name: Borysova, M.
name: Boudry, V.
name: Breton, D.
name: Brinkmann, R.
name: Bruschi, M.
name: Burkart, F.
name: Büßer, K.
name: Cavanagh, N.
name: Dal Corso, F.
name: Decking, W.
name: Deniaud, M.
name: Diner, O.
name: Dosselli, U.
name: Elad, M.
name: Epshteyn, L.
name: Esperante, D.
name: Ferber, T.
name: Firlej, M.
name: Fiutowski, T.
name: Fleck, K.
name: Fuster-Martinez, N.
name: Gadow, K.
name: Gaede, F.
name: Gallas, A.
name: Garcia Cabrera, H.
name: Gerstmayr, E.
name: Ghenescu, V.
name: Giorato, M.
name: Golubeva, N.
name: Grojean, C.
name: Grutta, P.
name: Grzelak, G.
name: Hallford, J.
name: Hartman, L.
name: Heinemann, B.
name: Heinzl, T.
name: Helary, L.
name: Hendriks, L.
name: Hoffmann, M.
name: Horn, D.
name: Huang, S.
name: Huang, X.
name: Idzik, M.
name: Irles, A.
name: Jacobs, R.
name: King, B.
name: Klute, M.
name: Kropf, A.
name: Kroupp, E.
name: Lahno, H.
name: Lasagni Manghi, F.
name: Lawhorn, J.
name: Levanon, A.
name: Levi, A.
name: Levinson, L.
name: Levy, A.
name: Levy, I.
name: Liberman, A.
name: Liss, B.
name: List, B.
name: List, J.
name: Lohmann, W.
name: Maalmi, J.
name: Madlener, T.
name: Malka, V.
name: Marsault, T.
name: Mattiazzo, S.
name: Meloni, F.
name: Miron, D.
name: Morandin, M.
name: Moroń, J.
name: Nanni, J.
name: Neagu, A. T.
name: Negodin, E.
name: Paccagnella, A.
name: Pantano, D.
name: Pietruch, D.
name: Pomerantz, I.
name: Pöschl, R.
name: Potlog, P. M.
name: Prasad, R.
name: Quishpe, R.
name: Ranken, E.
name: Ringwald, A.
name: Roich, A.
name: Salgado, F.
name: Santra, A.
name: Sarri, G.
name: Sävert, A.
name: Sbrizzi, A.
name: Schmitt, S.
name: Schulthess, I.
name: Schuwalow, S.
name: Seipt, D.
name: Simi, G.
name: Soreq, Y.
name: Spataro, D.
name: Streeter, M.
name: Swientek, K.
name: Tal Hod, N.
name: Teter, T.
name: Thiebault, A.
name: Thoden, D.
name: Trevisani, N.
name: Urmanov, R.
name: Vasiukov, S.
name: Walker, S.
name: Warren, M.
name: Wing, M.
name: Yap, Y. C.
name: Zadok, N.
name: Zanetti, M.
name: Żarnecki, A. F.
name: Zbińkowski, P.
name: Zembaczyński, K.
name: Zepf, M.
name: Zerwas, D.
name: Ziegler, W.
name: Zuffa, M.
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: 530 Physik

description: This Technical Design Report presents a detailed description of all aspects of the LUXE (Laser Und XFEL Experiment), an experiment that will combine the high-quality and high-energy electron beam of the European XFEL with a high-intensity laser, to explore the uncharted terrain of strong-field quantum electrodynamics characterised by both high energy and high intensity, reaching the Schwinger field and beyond. The further implications for the search of physics beyond the Standard Model are also discussed.
Additional file 1 of Women’s experiences and views on early breastfeeding during the COVID-19 pandemic in Norway: quantitative and qualitative findings from the IMAgiNE EURO study
Creators: name: Vik, Eline Skirnisdottir
name: Kongslien, Sigrun
name: Nedberg, Ingvild Hersoug
name: Mariani, Ilaria
name: Valente, Emanuelle Pessa
name: Covi, Benedetta
name: Lazzerini, Marzia
Publisher: name: figshare
Year: 2024
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Mental Health

description: Additional file 1.
Inhabiting a Comfortable Fiction of the Self: J.M. Coetzee’s            Summertime
Creators: name: Nashef, Hania
Publisher: name: Humanities Commons
Year: 2024
Subjects: subject: South Africa
subject: Fiction
subject: Creative nonfiction
subject: Autobiography
subject: Biographies
subject: Autobiographies

description: Abstract  In his email conversations with Arabella Kurtz in The Good Story: Exchanges on Truth, Fiction and Psychotherapy, J.M. Coetzee entertains the notion of settling on fictions of ourselves, which we are able to inhabit more comfortably than what is perceived as our real life.  In addition, he implies that in order to form fictions of ourselves, we require fictions created by others about us.  In essence, the author asserts that autobiographies and life-narratives are fictions, because they are constructions of a lived life. Summertime, the final part of the trilogy that began with Boyhood and Youth, works that read more like autobiographies, illustrates how the author settles on a fiction of the self that is ultimately more comfortable. The novel is about a person who is writing a post-mortem biography of the author, through interviews with a select few who apparently knew the deceased author well. With each person’s account, a different perspective is presented. The novel, which exposes the fictional element of auto/biography writing, does not end with a unified vision of what Coetzee was supposedly like but with contradictory personalities, depending on the narrator of the story. In essence, we are left with fictions of the real author.
title: Logicality and the picture theory of language
Creators: name: Trinh, Tue
Publisher: name: Humboldt-Universität zu Berlin
Year: 2024
Subjects: subject: Logicality
subject: Grammar
subject: Trivialities
subject: Wittgenstein
subject: Tractatus
subject: 100 Philosophie, Parapsychologie und Okkultismus, Psychologie

description: I argue that there is tension in Wittgenstein’s position on trivialities (i.e. tautologies and contradictions) in the Tractatus, as it contains the following claims: (A) sentences are pictures; (B) trivialties are not pictures; (C) trivialities are sentences. A and B follow from the “picture theory” of language which Wittgenstein proposes, while C contradicts it. I discuss a way to resolve this tension in light of Logicality, a hypothesis recently developed in linguistic research. Logicality states that trivialities are excluded by the grammar, and that under the right analysis sentences which look trivial are in fact contingent. The tools necessary to support Logicality, I submit, were not available to Wittgenstein at the time, which explains his commitment to C. I end the paper by commenting on some points of contact between analytic philosophy and the generative enterprise in linguistics which are brought into relief by the discussion.
Toward measurement of Nuclear Spin-Dependent(NSD) Parity Non-Conserving (PNC) interaction in 133Cs hyperfine ground states via two-pathway coherent control
Creators: name: Choi, Jungu
Publisher: name: Purdue University Graduate School
Year: 2019
Subjects: Electrical engineering not elsewhere classified

description: Weak interactions in an atomic system by external electromagnetic fields or nucleon-nucleon interaction cause perturbations in the wave-function and energy levels of electrons, which allow for transitions that are otherwise forbidden. Of particular interest are magnetic dipole (M1) transitions, Stark-induced transitions, and parity non-conserving (PNC) transitions. The PNC interaction in the hyperfine ground states is dominantly due to the anapole moment of the nucleus and there has been up-to-date only one such measurement carried out in any system; the Boulder group's ground-breaking measurement of the anapole moment in atomic cesium in 1997. Their result derived from two different hyperfine transitions, however, did not agree with the meson-coupling model from high energy physics experiments. Therefore, it is important to revisit the anapole moment through another method to cross-check the Boulder group's measurement. Our goal is to excite the nuclear-spin-dependent (NSD) PNC ground hyperfine transitions in cesium via radio-frequency (rf) and Raman excitation to directly determine the anapole moment. I present our progress toward measurement of the NSD transition in an atomic Cs beam geometry. We have developed a broadband rf cavity resonator to strongly suppress the magnetic dipole (M1) transition while enhancing the forbidden PNC electric dipole (E1) transition. We employed an injection locking scheme to generate a pair of phase-coherent Raman lasers far detuned from the cesium D2 line (852 nm) with a 9.2 GHz frequency difference. I report various measurement data from atomic signal via rf and Raman excitation. In the next generation of measurements, we will carry out interference experiments between rf and Raman transitions by varying the phase relations of the rf and Raman lasers fields. Finally, based on the measurements, I discuss a novel robust measurement technique involving interference of the Raman, M1 and EPNC contributions.
Characteristics and prognostic values of abdominal aortic branches calcification in hemodialysis patients
Creators: name: Shi, Wen
name: Xie, Xiaotong
name: Zhao, Yu
name: Liu, Yuqiu
name: Zhang, Xiaoliang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: Medicine
Cell Biology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Cancer
Hematology

description: Vascular calcification is highly prevalent and associated with mortality in hemodialysis patients. However, extreme splanchnic arterial calcification in calciphylaxis with poor prognosis raises questions regarding the reliability of previous vascular calcification scoring methods. Therefore, this study aimed to examine the distribution characteristics of abdominal aortic branch calcification and identify a more reliable predictor of mortality in hemodialysis patients. The cohort study included 237 hemodialysis patients. The distribution characteristics of abdominal aortic branch calcification were determined by quantifying the calcification volumes. The primary and secondary outcomes were all-cause mortality and new-onset cardiovascular events, respectively. We compared the prognostic values of abdominal aortic branch calcification and constructed a predictive nomogram model. The prevalence of abdominal vascular calcification in hemodialysis patients was 95.36%, with the highest prevalence in the abdominal aorta (88.61%) and internal iliac artery (85.65%). During a median follow-up period of 3.92 years, 137 patients died. Internal iliac artery and mesenteric artery calcification showed the greatest predictive values for mortality. Internal iliac artery calcification and serum albumin level were independently associated with mortality in hemodialysis patients (p < .001). The nomogram model constructed with internal iliac artery calcification, serum albumin level, age, and comorbid cardiovascular disease was well discriminative, calibrated, and clinically applicable for predicting 3-year survival. Abdominal aortic branch calcification, particularly internal iliac artery calcification, is a preferable prognostic predictor than abdominal aorta or coronary artery calcification in hemodialysis patients.
sj-docx-5-msj-10.1177_13524585211031128 – Supplemental material for Risk of depression in multiple sclerosis across disease-modifying therapies
Creators: name: Longinetti, Elisa
name: Frisell, Thomas
name: Englund, Simon
name: Reutfors, Johan
name: Fang, Fang
name: Piehl, Fredrik
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: Neurology and Neuromuscular Diseases
subject: FOS: Clinical medicine
subject: Aged Health Care

description: Supplemental material, sj-docx-5-msj-10.1177_13524585211031128 for Risk of depression in multiple sclerosis across disease-modifying therapies by Elisa Longinetti, Thomas Frisell, Simon Englund, Johan Reutfors, Fang Fang and Fredrik Piehl in Multiple Sclerosis Journal
Key RNA-binding proteins in renal fibrosis: a comprehensive bioinformatics and machine learning framework for diagnostic and therapeutic insights
Creators: name: Chen, Jie
name: Zhang, Binghan
name: Huang, Qixuan
name: Fang, Ronghua
name: Ren, Ziyu
name: Liu, Dongfang
Publisher: name: Taylor & Francis
Year: 2025
Subjects: subject: Biochemistry
subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Marine Biology
subject: Cancer
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology
subject: Computational Biology

description: Renal fibrosis is a critical factor in chronic kidney disease progression, with limited diagnostic and therapeutic options. Emerging evidence suggests RNA-binding proteins (RBPs) are pivotal in regulating cellular mechanisms underlying fibrosis. Utilizing an extensive GEO dataset (175 renal fibrosis and 99 normal kidney samples), we identified and validated key RBPs through integrated bioinformatics and machine learning approaches, including lasso and logistic regression models. Differentially expressed genes were analyzed for pathway enrichment using Gene Ontology and KEGG. Single-cell RNA sequencing delineated cell-specific RBP expression, and a murine unilateral ureteral obstruction (UUO) model provided experimental validation. A diagnostic model incorporating five RBPs (FKBP11, DCDC2, COL6A3, PLCB4, and GNB5) achieved high accuracy (AUC = 0.899) and robust external validation. These RBPs are implicated in immune-mediated pathways such as cytokine signaling and inflammatory responses. Single-cell analysis highlighted their expression in specific renal cell populations, underscoring functional diversity. Immunofluorescence linked FKBP11 with macrophage infiltration, suggesting its potential as a therapeutic target. his study identifies novel RBPs associated with renal fibrosis, advancing the understanding of its pathogenesis and offering actionable biomarkers and therapeutic targets. The integration of bioinformatics and machine learning emphasizes their translational potential in kidney care.
sj-pdf-1-ajs-10.1177_03635465211027180 – Supplemental material for The Validity, Reliability, and Responsiveness of the International Hip Outcome Tool–33 (iHOT-33) in Patients With Hip and Groin Pain Treated Without Surgery
Creators: name: Scholes, Mark J.
name: King, Matthew G.
name: Crossley, Kay M.
name: Jones, Denise M.
name: Semciw, Adam I.
name: Mentiplay, Benjamin F.
name: Heerey, Joshua J.
name: Lawrenson, Peter R.
name: Coburn, Sally L.
name: Johnston, Richard T.R.
name: Bell, Emily C.
name: Girdwood, Michael
name: Kemp, Joanne L.
Publisher: name: SAGE Journals
Year: 2021
Subjects: subject: 110314 Orthopaedics
subject: FOS: Clinical medicine
subject: 110604 Sports Medicine
subject: FOS: Health sciences
subject: 110323 Surgery

description: Supplemental material, sj-pdf-1-ajs-10.1177_03635465211027180 for The Validity, Reliability, and Responsiveness of the International Hip Outcome Tool–33 (iHOT-33) in Patients With Hip and Groin Pain Treated Without Surgery by Mark J. Scholes, Matthew G. King, Kay M. Crossley, Denise M. Jones, Adam I. Semciw, Benjamin F. Mentiplay, Joshua J. Heerey, Peter R. Lawrenson, Sally L. Coburn, Richard T.R. Johnston, Emily C. Bell, Michael Girdwood and Joanne L. Kemp in The American Journal of Sports Medicine