cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A survey of knowledge, attitudes, barriers and support needs in providing hepatitis B care among GPs practising in Australia
Creators: name: Xiao, Y
name: van Gemert, C
name: Howell, J
name: Wallace, John
name: Richmond, Jacqueline
name: Adamson, E
name: Thompson, A
name: Hellard, M
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4203
subject: Health services and systems

description: Background: In Australia, only 22% of people with chronic hepatitis B (CHB) are clinically managed; and a national effort is engaging primary care workforce in providing CHB-related care. This study explored CHB-related knowledge, attitudes, barriers and support needs of general practitioners (GPs). Methods: A survey was sent to a random sample of 1,000 Australian GPs in April- October 2018; 134 of 978 eligible GPs completed the questionnaire (14%). Results: Respondents had high knowledge of at-risk populations (> 79%) and hepatitis B serology (82%), and most saw hepatitis B testing and monitoring as part of their work (95% and 86%, respectively). However, the survey revealed low knowledge, awareness and intention with respect to hepatitis B treatment: 23% correctly understood treatment initiation; 40% were aware that treatment for CHB could be dispensed in the community; 23% agreed that prescribing was part of their work. Lack of time was considered the greatest barrier (38%) and clear guidelines was the most important facilitator to providing care (72%). Conclusion: Interventions are needed to generate interest and skills to provide CHB-related care by GPs.
6Dof Input Device Integration For Xct Volume Visualisation
Creators: name: Turner, Martin
name: Morris, Tim
name: Sandoval, Mario
name: Worthington, Sam
Publisher: name: Zenodo
Year: 2016
Subjects: 6dof, HCI, Volume Visualisation, Interraction

description: Any possible movement of a rigid body, no matter how complex, can be expressed as a combination of three translations and three rotations, the basic six degrees of freedom (6DoF) [LM10]. Volume visualisation as exploited in tomography packages, (e.g. Avizo (FEI), ImageJ, Paraview TomVis or Drishti) allow for multiple other parameters and other rigid bodies to be changed. Current users of these systems often have to exploit a single mouse and contrived keystrokes for even the simplest of data exploration and animation task.

Using a hand, a user can send and receive information through force/torque and displacement/rotation; which are translated by drivers for interpretation by the application. HCI studies classified input devices into two groups: isotonic (senses displacement or free movement with zero or constant resistance; e.g. the mouse) and isometric devices (senses force without perceptibly movement; e.g. a joystick) [Zha95].  Recently a new 6DoF device (Wing [Wor14]), allows one hand to combine both of these.

A new python driver, with improved calibration, has been written to link with the Drishti package [Lim12]; which has been evaluated with XCT users. Results showed user preference and comfort criteria (included expected cost), as well as timed specific tasks for comparative XCT viewing  - creating a system that has potential ease of use and speed up in exploration and discovery.

Future work is planned to include multiple Wing devices allowing then for simultaneous interaction; for example manipulating both light parameters and object position; or changing clipping plane and object transparency.
description: Presented at ToScA 2016
description: {"references": ["[LM10] LAVIOLA JR. J. J., MARKS R. L.: An introduction to 3D spatial interaction with video game motion controllers. In ACM SIGGRAPH 2010 Courses (New York, NY, USA, 2010), SIGGRAPH \u201910, ACM, pp. 2:1\u20132:78", "[Wor14] WORTHINGTON S.: Wing: Beyond the Mouse. http://www.worthingtonsharpe.com/", "[Lim12] LIMAYE A.: Drishti: a Volume Exploration and Presentation Tool. Proc. SPIE 8506, Developments in X-Ray Tomography VIII, 85060X (October 17, 2012).", "[Zha95] ZHAI S.: Human Performance in Six Degree of Freedom Input Control; Thesis, University of Toronto 1995"]}
Brush-like Polymer Prodrug with Aggregation-Induced Emission Features for Precise Intracellular Drug Tracking
Creators: name: Naghibi, S
name: Sabouri, Soheila
name: Hong, Yuning
name: Jia, Z
name: Tang, Y
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3401
subject: Analytical chemistry

description: In this study, a brush-like polymer with aggregation-induced emission (AIE) features was synthesized for drug delivery and intracellular drug tracking. The polymer consisting of tetraphenylethene (TPE) chain-end as well as oligo-poly (ethylene glycol) (PEG) and hydrazine functionalities was successfully synthesized through copper (0)-mediated reversible-deactivation radical polymerization (Cu0-mediated RDRP). Anticancer drug doxorubicin (DOX) was conjugated to the polymer and formed a prodrug named TPE-PEGA-Hyd-DOX, which contains 11% DOX. The hydrazone between DOX and polymer backbone is a pH-sensitive linkage that can control the release of DOX in slightly acidic conditions, which can precisely control the DOX release rate. The drug release of 10% after 96 h in normal cell environments compared with about 40% after 24 h in cancer cell environments confirmed the influence of the hydrazone bond. The ratiometric design of fluorescent intensities with peaks at 410 nm (emission due to AIE feature of TPE) and 600 nm (emission due to ACQ feature of DOX) provides an excellent opportunity for this product as a precise intracellular drug tracker. Cancer cells confocal microscopy showed negligible DOX solution uptake, but an intense green emission originated from prodrug uptake. Moreover, a severe red emission in the DOX channel confirmed a promising level of drug release from the prodrug in the cytoplasm. The merged images of cancer cells confirmed the high performance of the TPE-PEGA-Hyd-DOX compound in the viewpoints of cellular uptake and drug release. This polymer prodrug successfully demonstrates low cytotoxicity in healthy cells and high performance in killing cancer cells.
Four actions Australia should take to advance equitable global access to COVID‐19 vaccines
Creators: name: Gleeson, Deborah
name: Tenni, Brigitte
name: Townsend, Belinda
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4202
subject: Epidemiology
classificationCode: 4203
subject: Health services and systems
classificationCode: 4206
subject: Public health

description: We argue that there are four actions Australia should take to advance equitable global access to COVID-19 vaccines: produce, donate, redistribute and fund more COVID-19 vaccines for LICs; support a broad and workable TRIPS Waiver; invest in building production capacity in LMICs; and impose conditions on public funding for R&D for COVID-19 health products and technologies to ensure know-how is shared and pricing is fair.
Meaningful Data Metrics for Whom?
Creators: name: Borgman, Christine
Publisher: name: Zenodo
Year: 2022
Subjects: Make Data Count BEGIN webinar
DOI
Digital Object Identifier
metadata
metrics

description: Make Data Count (MDC) is a scholarly change initiative, made up of researchers and open infrastructure experts, building and advocating for evidence-based open data metrics. Throughout MDC’s tenure, various areas key to the development of research data assessment metrics have been identified. Please join a Spring seminar and discussion series centered around priority work areas, adjacent initiatives to learn from, and steps that can be taken immediately to drive diverse research communities towards assessment and reward for open data.

 The third and last webinar in our series “BEGIN: metadata for meaningful metrics” will look at next steps to develop responsible and fair data metrics that can reflect the use and impact of research datasets and help elevate them to first-class scholarly outputs. We’ll focus on necessary metadata to construct metrics that take into account characteristics and contexts of open data across disciplines. "Meaningful Data Metrics for Whom?" is the question Christine L. Borgman addresses in her talk. A recording of the talk can be found here: https://www.youtube.com/watch?v=Qtpyp_mhx4A&t=413s
Molecular taxonomy and the evolution theory in light of emerging bioinformatic and cosmological data
Creators: name: Shchyogolev, Sergei Y.
Publisher: name: Journal of Bioinformatics and Genomics
Year: 2016

description: A brief review is given of recent advances in the taxonomic study of organisms and current views on biological evolution and the origin of life. A discussion is presented on how the treelike and net components contribute to the topology of phylogenetic constructs, with account taken of the prevailing role of horizontal gene transfer in prokaryote evolution and life. Approaches are described to the rational selection and practical use of phylogenetic markers (including 16S rRNA gene DNA sequences) in biomedical (including metagenomic) applications with traditional and nontraditional (large) amounts of molecular genetic data. Emerging results from taxonomic studies of the Earth’s biota and the methods of their generation are demonstrated. It is noted that the current developments in particle physics and in cosmology have important implications for solving paradoxes associated with the vanishingly small probability of some fundamental processes of prebiological and biological evolution.
description: Journal of Bioinformatics and Genomics, No 1 (1) (2016)
SHARYAR DÁSTANÍNDA GÓNERGEN SÓZLERDIŃ QOLLANÍLÍWÍ
Creators: name: Sipatdinova, Qumar
Publisher: name: Zenodo
Year: 2024

description: Bul maqalada Qaraqalpaq xalıq dástannı bolǵan "Sharyar" dástanında qollanılǵan gónergen sózler hám olardıń túsindirme sózlikleri berilgen.
In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review
Creators: name: Kakarla, Akesh Babu
name: Kong, Ing
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 40
subject: Engineering
classificationCode: 4016
subject: Materials engineering
subject: FOS: Materials engineering
classificationCode: 4018
subject: Nanotechnology
subject: FOS: Nanotechnology

description: Boron nitride nanotubes (BNNTs) are an exciting class of nanomaterials due to their unique chemical and physical characteristics. In recent decades, BNNTs have gained huge attention in research and development for various applications, including as nano‐fillers for composites, semiconductor devices, hydrogen storage, and as an emerging material in biomedical and tissue engineering applications. However, the toxicity of BNNTs is not clear, and the biocompatibility is not proven yet. In this review, the role of BNNTs in biocompatibility studies is assessed in terms of their characteristics: cell viability, proliferation, therapeutic outcomes, and genotoxicity, which are vital elements for their prospective use in biomedical applications. A systematic review was conducted utilising the databases Scopus and Web of Science (WOS) (2008–2022). Additional findings were discovered manually by snowballing the reference lists of appropriate reviews. Only English-language articles were included. Finally, the significant analysis and discussion of the chosen articles are presented.
Predicting The Wind Speeds Of Solar-Like Stars
Creators: name: Jardine, Moira
name: See, V.
name: Vidotto, A.
Publisher: name: Zenodo
Year: 2016

description: Some aspects of stellar magnetic activity such as X-ray emission are relatively easy to observe, while others, such as the geometry of the magnetic field are rather more difficult. Indeed, typically only the large-scale (or low-order) components of the field can be mapped. Most elusive of all is the hot, tenuous stellar wind, yet the wind speed is a crucial quantity governing the angular momentum loss of the star. We demonstrate, however, that wind speeds can be predicted reliably even from fairly low-resolution magnetograms. We use an empirically-derived model of the solar wind that predicts the distribution of wind speeds based on surface magnetograms. Using solar magnetic field measurements spanning several magnetic cycles, we demonstrate how changes in the surface magnetic field on various length-scales affect the coronal structure and hence the wind speed. We find that only low-order field components are needed to characterise the wind speed. We compare the variations in wind speed with variations in the X-ray emission over several cycles and show that while the small-scale field has a significant effect on Lx, it has little effect on the wind speed. This suggests that the large number of stellar magnetograms that are becoming available can be used to predict the stellar wind speeds.
description: Contributed talk at the Splinter Session on "Variability of Solar/Stellar Magnetic Activity" (http://coolstars19.com/splinters/stellar-var/index.html) at the "Cool Stars 19" Workshop
The Importance of Ethnographic Observation in Grounded Theory Research
Creators: name: Fitzgerald, Jarrah
name: Mills, Jane
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 4410
subject: Sociology
subject: FOS: Sociology

description: Even though observational data have contributed to grounded theory research since the method's inception, it is interview data that is most often analyzed. In this article we argue for the greater inclusion of ethnographic observational data in grounded theory research, as this practice offers several benefits. By witnessing and experiencing for oneself the various social processes experienced by and impacting on participants, ethnographic observational data represent both a unique source of data and a way to enhance one's theoretical sensitivity. Additional benefits relate to sampling and recruitment, the development of interview guides, coding, and analysis. As such, conducting ethnographic observations supports grounded theory methods and can enhance the use of interview data to improve the quality of final theory. The writing of observational field notes overlays with traditional grounded theory memoing, compounding the analytical benefits to researchers, while providing an audit trail of the research process, and supporting reflexive practice.
A Practical Guide to Inferring Multi-Omics Networks in Plant Systems
Creators: name: Clark, Natalie M
name: Hurgobin, Bhavna
name: Kelley, Dior R
name: Lewsey, Mathew
name: Walley, Justin W
Publisher: name: La Trobe
Year: 2023
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 3102
subject: Bioinformatics and computational biology
classificationCode: 3404
subject: Medicinal and biomolecular chemistry

description: No description supplied.
Data Metrics and the Reward System of Science
Creators: name: Costas, Rodrigo
Publisher: name: Zenodo
Year: 2022
Subjects: Make Data Count BEGIN webinar
DOI
Digital Object Identifier
metrics
metadata

description: Make Data Count (MDC) is a scholarly change initiative, made up of researchers and open infrastructure experts, building and advocating for evidence-based open data metrics. Throughout MDC’s tenure, various areas key to the development of research data assessment metrics have been identified. Please join a Spring seminar and discussion series centered around priority work areas, adjacent initiatives to learn from, and steps that can be taken immediately to drive diverse research communities towards assessment and reward for open data.

 The third and last webinar in our series “BEGIN: metadata for meaningful metrics” will look at next steps to develop responsible and fair data metrics that can reflect the use and impact of research datasets and help elevate them to first-class scholarly outputs. We’ll focus on necessary metadata to construct metrics that take into account characteristics and contexts of open data across disciplines. In his talk, Rodrigo Costas addresses the issue of data metrics and the reward system of science. A recording of the talk can be found here: https://www.youtube.com/watch?v=Qtpyp_mhx4A&t=853s
The Effect of Outdoor Environmental Exposure on Readmission Rates for Children and Adolescents with Asthma—A Systematic Review
Creators: name: Smaller, L
name: Batra, Mehak
name: Erbas, Bircan
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4202
subject: Epidemiology

description: The burden of asthma readmission for children and adolescents is approximately 10% worldwide. Research has been synthesised for behavioural and indoor impacts; however, no such synthesis has been conducted for outdoor environmental exposures. This systematic review aims to evaluate and synthesise the impact the outdoor environment has on readmission rates for children or adolescents with asthma. We conducted a systematic search of seven databases and hand searched reference lists of articles published up until 18 January 2021. There were 12 out of 392 studies eligible for inclusion. Overall, most studies showed that outdoor environments impact on readmission; however, the strength of association is seen to be stronger in a particular subpopulation of each study depending on the exposure investigated. The evidence for the association between outdoor environmental exposure and readmission rates for children or adolescents with asthma is increasing; however, it is complicated by potential confounders such as socioeconomic factors, ethnicity, indoor air pollutants, and other behavioural factors. Further research is required to differentiate between them. Additionally, further studies need to be undertaken in further countries other than the United States of America to understand the full relationship.
Supporting LGBTQA+ peoples’ recovery from sexual orientation and gender identity and expression change efforts
Creators: name: Jones, Tiffany
name: Power, Jennifer
name: Jones, Timothy
name: Pallotta-Chiarolli, Maria
name: Despott, Nathan
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: No description supplied
ФУҚАРОЛИК ТАЪЛИМ ЁШЛАРНИНГ ФУҚАРОЛИК ПОЗИЦИЯСИНИ РИВОЖЛАНТИРИШНИНГ АСОСИЙ ПОЙДЕВОРИ
Creators: name: Оринбетов, Ниетулла
Publisher: name: Zenodo
Year: 2024

description: Мақолада ёшларнинг фуқаролик позициясини ривожлантиришда фуқаролик таълимнинг роли ва ўнинг аҳамияти ҳақида сўз этилади. Шунингдек ёшларнинг фуқаролик позициясини ривожлантиришда фуқаролик таълимнинг таъсир этиш йўлларига алоҳида эътибор берилган.
Stemformatics: a visualisation platform for well-curated biological sequence data
Creators: name: Chen, Tyrone
name: Mosbergen, Rowland
name: Korn, Othmar
name: Wells, Christine
Publisher: name: F1000Research
Year: 2016

description: The wider accessibility of sequencing technology to address biological questions has greatly increased the quantity of raw data available to the research community. These “big-data” experiments are publicly available online in computational databases, allowing interested parties to attempt to reproduce and further analyse datasets. However, public repositories were developed from a data generator's perspective instead of a data user. As a result, the data is uncurated, which requires experimental design and data quality to be assessed in the specific context of each dataset.

To address this issue, we have formulated a biology-centric approach. Stemformatics was developed with the goal of combining biological data and computational as well as statistical methods in a user-friendly format for stem cell researchers. To date, the Stemformatics platform hosts 490 datasets, of which 305 are publicly available. Every dataset has passed through rigorous quality control steps, and has been manually curated by a biologist for experimental design and cell phenotypes. At present, available datasets include gene expression data from various platforms, covering the range of microarrays, RNA-Seq, ChIP-Seq, proteomics and others. A major future challenge will be hosting and visualizing single-cell data.

Currently, pipelines and visualisation tools are being developed to process single cell transcriptomics data. The ultimate goals of this would be to streamline the continuous addition of high-quality single-cell experiments to our database and at the same time, allow for an integrated visualisation of these major -omics data at a single-cell resolution.

Stemformatics holds both human and mouse expression data, and support for additional model organisms is being planned. To improve efficiency, our interface is designed for quick screening of individual or multiple gene expression levels, both across and/or within experiments. It is possible for users to share views with collaborators and store lists of genes. Stemformatics is funded as part of the ARC initative “Stem Cells Australia”. We are freely accessible to all academic groups and have an international community of users.
Flow artifact mimicking atrial thrombus/mass
Creators: name: Keshavamurthy, Jayanth
Publisher: name: EURORAD
Year: 2016
Subjects: subject: Cardiac
subject: CT
subject: Contrast agent-intravenous
subject: Artefact

description: Clinical History Image Findings Discussion Find Diagnosis Differential Diagnosis
description: male, 79 years
description: Clinical History: 79 year old male with chest pain radiating to the back. Hypertensive with concern for aortic dissection. Final Diagnosis: Flow artifact simulating pseudothrombus/mass
Model Checking and Model-Based Testing : Improving Their Feasibility by Lazy Techniques, Parallelization, and Other Optimizations
Creators: name: Faragó, David
Publisher: name: Karlsruhe
Year: 2016
Subjects: model checking
model-based testing
laziness
parallelization
heuristics

description: This thesis focuses on the lightweight formal method of model-based testing for checking safety properties, and derives a new and more feasible approach. 
For liveness properties, dynamic testing is impossible, so feasibility is increased by specializing on an important class of properties, livelock freedom, and deriving a more feasible model checking algorithm for it.
All mentioned improvements are substantiated by experiments.
Tetraspanin CD82 restrains phagocyte migration but supports macrophage activation
Creators: name: McGowan, ENS
name: Wong, O
name: Jones, E
name: Nguyen, J
name: Wee, J
name: Demaria, MC
name: Deliyanti, D
name: Johnson, Chad
name: Hickey, MJ
name: McConville, MJ
name: Wilkinson-Berka, JL
name: Wright, MD
name: Binger, Katrina
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3207
subject: Medical microbiology

description: Phagocytes migrate into tissues to combat infection and maintain tissue homeostasis. As dysregulated phagocyte migration and function can lead to inflammation or susceptibility to infection, identifying molecules that control these processes is critical. Here, we show that the tetraspanin CD82 restrains the migration of neutrophils and macrophages into tissues. Cd82−/− phagocytes exhibited excessive migration during in vivo models of peritoneal inflammation, superfusion of CXCL1, retinopathy of prematurity, and infection with the protozoan parasite L. mexicana. However, with the latter, while Cd82−/− macrophages infiltrated infection sites at higher proportions, cutaneous L. mexicana lesions were larger and persisted, indicating a failure to control infection. Analyses of in vitro bone-marrow-derived macrophages showed CD82 deficiency altered cellular morphology, and impaired gene expression and metabolism in response to anti-inflammatory activation. Altogether, this work reveals an important role for CD82 in restraining phagocyte infiltration and mediating their differentiation in response to stimulatory cues.
China, Gender Issues, Medical Philosophy and Measurement Scales
Creators: name: Carey, Lindsay
name: Koenig, Harold G
name: Hill, Terrence
name: Gabbay, Ezra
name: Cohen, Jeffrey
name: Aiken, Carl
name: Drummond, David
name: Hart, Curtis
name: Carey, Jacinda
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4206
subject: Public health
classificationCode: 52
subject: Psychology
subject: FOS: Psychology
classificationCode: 5203
subject: Clinical and health psychology

description: No description supplied
Supplementary document for Visible femtosecond fiber laser - 6437662.pdf
Creators: name: Lord, Marie-Pier
name: Olivier, Michel
name: Bernier, Martin
name: Vallee, Real
Publisher: name: Optica Publishing Group
Year: 2025
Subjects: Uncategorized

description: This supplemental document presents a mathematical model and a numerical simulator for visible-wavelengths Pr3+-doped fluoride fiber lasers mode-locked through the mechanism of nonlinear polarization evolution of light in optical fibers.
Can fire-age mosaics really deal with conflicting needs of species? A study using population hotspots of multiple threatened birds
Creators: name: Verdon, Simon
name: Clarke, Michael
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3103
subject: Ecology
classificationCode: 3109
subject: Zoology
classificationCode: 41
subject: Environmental sciences
classificationCode: 4101
subject: Climate change impacts and adaptation
classificationCode: 4102
subject: Ecological applications
classificationCode: 4104
subject: Environmental management
classificationCode: 410404
subject: Environmental management

description: Locations that support high densities of a species (‘population hotspots’) often have a disproportionate influence on species' persistence. In fire-prone ecosystems, managers attempting to promote population hotspots of multiple species must understand how hotspot locations might shift with post-fire succession and how much overlap exists in the locations of population hotspots for multiple species. Mangers are then tasked with resolving fire-management conflicts in overlapping locations. We studied three co-occurring threatened bird species in a fire-prone ‘mallee’ region of south-eastern Australia. We undertook field surveys for each species (1,508 surveys, 540 sites; 9-ha each). We used N-mixture models to determine (a) what factors affect species' density (including post-fire succession); (b) species' population sizes; (c) locations of species' current population hotspots and locations that may become population hotspots in the future as the post-fire successional state changes and (d) the degree of overlap in the current and possible future hotspots of species. We found substantial variation in the densities of the three species across the study area, with roughly half of each species' population occurring in only 20% of potential habitat (i.e. population hotspots). All species shared a preference for subtle depressions in the landscape, resulting in substantial overlap in their population hotspots. Two species had contrasting responses to post-fire succession in the subtle depressions. As a result, there was only a narrow post-fire period that supported population hotspots of both species, creating a challenge for fire managers in these shared locations. Synthesis and applications. Many studies make vague recommendations for fire-age mosaics that do not provide conservation managers with the detail they need to implement appropriate fire-age mosaics. By contrast, we explicitly quantify, then balance the conflicting post-fire needs of species in locations that support population hotspots of multiple species. Using this approach, we develop principles to guide the implementation of fire-age mosaics in such locations. This approach represents an important step towards applying fire-age mosaic theory to effectively support species conservation.
On the Origin of Queries: Where Chat Reference Questions Begin
Creators: name: Dempsey, Paula
name: Warner, Adrienne
name: Lux, Vera
name: Rich, Linda
Publisher: name: University of Illinois at Chicago
Year: 2022
Subjects: subject: Information Systems
subject: FOS: Computer and information sciences
subject: Library and Information Studies
subject: FOS: Media and communications

description: Academic libraries providing chat reference services have a range of options for where and how library users can engage with chat providers. These entry points can be static or proactively invite users into the service. The study compares the URLs from which users entered chat reference at three large public research libraries in the United States. The URLs show where users were when they sought assistance with library tasks. This exploratory investigation is important for extending knowledge of user help-seeking behavior and how chat service configuration may impact use. Data are variables related to chat interactions (n = 19,839) at Bowling Green State University (BGSU), University of Illinois Chicago (UIC), and University of New Mexico (UNM) in three semesters 2019–20. Findings show users originated most chats from either the library website or discovery layer; chat initiations from other resources are minimal; chat traffic increased at all three during the COVID-19 pandemic.
Classroom Movement Breaks and Physically Active Learning Are Feasible, Reduce Sedentary Behaviour and Fatigue, and May Increase Focus in University Students: A Systematic Review and Meta-Analysis
Creators: name: Lynch, Julia
name: O’Donoghue, G
name: Peiris, Casey
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 39
subject: Education
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4206
subject: Public health

description: Background: University students are mostly sedentary in tertiary education settings which may be detrimental to their health and learning. This review aimed to examine the feasibility and efficacy of classroom movement breaks (CMB) and physically active learning (PAL) on physical and cognitive outcomes in university students in the tertiary setting. Methods: Five electronic databases (MEDLINE, CINAHL, Embase, PsychINFO, and PubMed) were searched for articles published up until November 2021. Manual searching of reference lists and citation tracking were also completed. Two reviewers independently applied inclusion and exclusion criteria and completed quality assessment. Articles were included if they evaluated CMB or PAL interventions delivered to university students in a tertiary setting. Results: Of the 1691 articles identified, 14 studies with 5997 participants met the inclusion criteria. Average study quality scores were poor for both CMB and PAL studies. CMBs and PAL are feasible in the tertiary setting and increase physical activity, reduce sedentary behaviour, increase wellbeing, and reduce fatigue in university students. In addition, CMBs increased student focus and attention in class and PAL had no detrimental effect on academic performance. Conclusions: University educators should feel confident in introducing CMB and/or PAL interventions into their classes to improve student health and wellbeing.
Australian guideline on prevention of foot ulceration: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease
Creators: name: Kaminski, Michelle
name: Golledge, J
name: Lasschuit, JWJ
name: Schott, KH
name: Charles, J
name: Cheney, J
name: Raspovic, Anita
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3202
subject: Clinical sciences
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 4201
subject: Allied health and rehabilitation science
classificationCode: 4203
subject: Health services and systems
classificationCode: 4207
subject: Sports science and exercise

description: Background: There are no current Australian guidelines on the prevention of diabetes-related foot ulceration (DFU). A national expert panel aimed to systematically identify and adapt suitable international guidelines to the Australian context to create new Australian evidence-based guidelines on prevention of first-ever and/or recurrent DFU. These guidelines will include for the first-time considerations for rural and remote, and Aboriginal and Torres Strait Islander peoples. Methods: The National Health and Medical Research Council procedures were followed to adapt suitable international guidelines on DFU prevention to the Australian health context. This included a search of public databases after which the International Working Group on the Diabetic Foot (IWGDF) prevention guideline was deemed the most appropriate for adaptation. The 16 IWGDF prevention recommendations were assessed using the ADAPTE and GRADE systems to decide if they should be adopted, adapted or excluded for the new Australian guideline. The quality of evidence and strength of recommendation ratings were re-evaluated with reference to the Australian context. This guideline underwent public consultation, further revision, and approval by national peak bodies. Results: Of the 16 original IWGDF prevention recommendations, nine were adopted, six were adapted and one was excluded. It is recommended that all people at increased risk of DFU are assessed at intervals corresponding to the IWGDF risk ratings. For those at increased risk, structured education about appropriate foot protection, inspection, footwear, weight-bearing activities, and foot self-care is recommended. Prescription of orthotic interventions and/or medical grade footwear, providing integrated foot care, and self-monitoring of foot skin temperatures (contingent on validated, user-friendly and affordable systems becoming available in Australia) may also assist in preventing DFU. If the above recommended non-surgical treatment fails, the use of various surgical interventions for the prevention of DFU can be considered. Conclusions: This new Australian evidence-based guideline on prevention of DFU, endorsed by 10 national peak bodies, provides specific recommendations for relevant health professionals and consumers in the Australian context to prevent DFU. Following these recommendations should achieve better DFU prevention outcomes in Australia.
Distribution, composition and environmental correlates of high-altitude gravelly pavement herbfields in north-eastern Victoria, Australia
Creators: name: Blackburn-Smith, Alexandra
name: Morgan, John
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3103
subject: Ecology
classificationCode: 3104
subject: Evolutionary biology
classificationCode: 3108
subject: Plant biology

description: Context: Gravelly pavement herbfields are a rare, geographically restricted community found in high mountain areas of south-eastern Australia. Gravelly pavement plant communities occur where there is continuous waterflow, with vegetation comprising sparse, semi-aquatic species on a rock or gravel substratum. Aims: This study aimed to further the understanding of the community on the Bogong High Plains, Victoria, by asking questions relating to their location, structure and floristic composition. In particular, we ask what determines the distribution of pavement communities at the landscape-scale; and what abiotic factors govern between- A nd within-site vegetation patterns? Results: Gravelly pavement communities were associated with groundwater outflows and are likely to be formed by an interaction between surface waterflow and slope. This work adds to the current understanding of wetland types in high-mountain Australia because, to our knowledge, this relationship has not been previously described. Floristic patterns vary with slope and elevation, with high-elevation pavements on steep slopes being floristically dissimilar to those at lower elevation on flatter slopes. Species richness was consistent across sites and only a few species were found at high abundance. Within-site patterning is apparent in most pavements, attributable to abiotic factors such as rockiness and water availability, leading to characteristic vegetation patterns. Species such as the sedge Oreobolus pumilio occur on the margins of pavements where water levels are variable, whereas forbs such as Psychrophila introloba are typically found in the middle of pavements where there is constant water supply. Conclusions: Gravelly pavement communities are groundwater-dependant ecosystems, restricted at the landscape-scale and contain many rare species and, as such, deserve higher levels of protection than is currently offered.
Ancestral dietary change alters the development of Drosophila larvae through MAPK signalling
Creators: name: Towarnicki, SG
name: Youngson, NA
name: Corley, SM
name: St. John, JC
name: Melvin, Richard
name: Turner, N
name: Morris, MJ
name: Ballard, John
Publisher: name: La Trobe
Year: 2024
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3105
subject: Genetics

description: Studies in a broad range of animal species have revealed phenotypes that are caused by ancestral life experiences, including stress and diet. Ancestral dietary macronutrient composition and quantity (over- and under-nutrition) have been shown to alter descendent growth, metabolism and behaviour. Molecules have been identified in gametes that are changed by ancestral diet and are required for transgenerational effects. However, there is less understanding of the developmental pathways altered by inherited molecules during the period between fertilization and adulthood. To investigate this non-genetic inheritance, we exposed great grand-parental and grand-parental generations to defined protein to carbohydrate (P:C) dietary ratios. Descendent developmental timing was consistently faster in the period between the embryonic and pupal stages when ancestors had a higher P:C ratio diet. Transcriptional analysis revealed extensive and long-lasting changes to the MAPK signalling pathway, which controls growth rate through the regulation of ribosomal RNA transcription. Pharmacological inhibition of both MAPK and rRNA pathways recapitulated the ancestral diet-induced developmental changes. This work provides insight into non-genetic inheritance between fertilization and adulthood.
Ancestral dietary change alters the development of Drosophila larvae through MAPK signalling
Creators: name: Towarnicki, SG
name: Youngson, NA
name: Corley, SM
name: St. John, JC
name: Melvin, RG
name: Turner, N
name: Morris, MJ
name: Ballard, John
Publisher: name: La Trobe
Year: 2022

description: Studies in a broad range of animal species have revealed phenotypes that are caused by ancestral life experiences, including stress and diet. Ancestral dietary macronutrient composition and quantity (over- and under-nutrition) have been shown to alter descendent growth, metabolism and behaviour. Molecules have been identified in gametes that are changed by ancestral diet and are required for transgenerational effects. However, there is less understanding of the developmental pathways altered by inherited molecules during the period between fertilization and adulthood. To investigate this non-genetic inheritance, we exposed great grand-parental and grand-parental generations to defined protein to carbohydrate (P:C) dietary ratios. Descendent developmental timing was consistently faster in the period between the embryonic and pupal stages when ancestors had a higher P:C ratio diet. Transcriptional analysis revealed extensive and long-lasting changes to the MAPK signalling pathway, which controls growth rate through the regulation of ribosomal RNA transcription. Pharmacological inhibition of both MAPK and rRNA pathways recapitulated the ancestral diet-induced developmental changes. This work provides insight into non-genetic inheritance between fertilization and adulthood.
Noticed and then Forgotten: Gender in Alcohol Policy Stakeholder Responses to Alcohol and Violence
Creators: name: Farrugia, Adrian
name: Moore, David
name: Keane, H
name: Ekendahl, M
name: Graham, K
name: Duncan, Duane
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 44
subject: Human society
classificationCode: 4407
subject: Policy and administration
classificationCode: 4408
subject: Political science
subject: FOS: Political science

description:  No description supplied
Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes
Creators: name: Mohanty, B
name: Orts, J
name: Wang, Geqing
name: Nebl, S
name: Alwan, WS
name: Doak, BC
name: Williams, ML
name: Heras, Begona
name: Mobli, M
name: Scanlon, MJ
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 31
subject: Biological sciences
subject: FOS: Biological sciences
classificationCode: 3101
subject: Biochemistry and cell biology
classificationCode: 34
subject: Chemical sciences
subject: FOS: Chemical sciences
classificationCode: 3401
subject: Analytical chemistry
classificationCode: 3404
subject: Medicinal and biomolecular chemistry

description: Structures of protein–ligand complexes provide critical information for drug design. Most protein–ligand complex structures are determined using X-ray crystallography, but where crystallography is not able to generate a structure for a complex, NMR is often the best alternative. However, the available tools to enable rapid and robust structure determination of protein–ligand complexes by NMR are currently limited. This leads to situations where projects are either discontinued or pursued without structural data, rendering the task more difficult. We previously reported the NMR Molecular Replacement (NMR2) approach that allows the structure of a protein–ligand complex to be determined without requiring the cumbersome task of protein resonance assignment. Herein, we describe the NMR2 approach to determine the binding pose of a small molecule in a weak protein–ligand complex by collecting sparse protein methyl-to-ligand NOEs from a selectively labeled protein sample and an unlabeled ligand. In the selective labeling scheme all methyl containing residues of the protein are protonated in an otherwise deuterated background. This allows measurement of intermolecular NOEs with greater sensitivity using standard NOESY pulse sequences instead of isotope-filtered NMR experiments. This labelling approach is well suited to the NMR2 approach and extends its utility to include larger protein–ligand complexes.
Cardiac cycle: an observational/interventional study protocol to characterise cardiopulmonary function and evaluate a home-based cycling program in children and adolescents born extremely preterm
Creators: name: Clarke, Melanie
name: Willis, Claire
name: Cheong, JLY
name: Cheung, MMH
name: Mynard, JP
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 32
subject: Biomedical and clinical sciences
classificationCode: 3213
subject: Paediatrics
classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences
classificationCode: 52
subject: Psychology
subject: FOS: Psychology

description: Introduction: Extremely preterm (EP)/extremely low birthweight (ELBW) individuals may have an increased risk for adverse cardiovascular outcomes. Compared with term-born controls, these individuals have poorer lung function and reduced exercise capacity. Exercise interventions play an important role in reducing cardiopulmonary risk, however their use in EP/ELBW cohorts is unknown. This study, cardiac cycle, aims to characterise the cardiopulmonary system of children and adolescents who were born EP compared with those born at term, following acute and chronic exercise bouts. Methods and analysis: The single-centre study comprises a home-based exercise intervention, with physiological characterisation at baseline and after completion of the intervention. Fifty-eight children and adolescents aged 10-18 years who were born EP and/or with ELBW will be recruited. Cardiopulmonary function assessed via measures of blood pressure, arterial stiffness, capillary density, peak oxygen consumption, lung clearance indexes and ventricular structure/function, will be compared with 58 age-matched and sex-matched term-born controls at baseline and post intervention. The intervention will consist of a 10-week stationary cycling programme, utilising Zwift technology. Ethics and dissemination: The study is approved by the Ethics Committee of the Royal Children's Hospital Melbourne under HREC2019.053. Results will be disseminated via peer-reviewed journal regardless of outcome. Trial registration number 12619000539134, ANZCTR
HSbooster.eu Webinar: Europe's Digital Future - Standards and Innovation in Data Spaces - Slides / Presentations
Creators: name: Ferguson, Nicholas
name: Janssen, Coen
name: Steinbuss, Sebastian
name: Lindner, René
name: Brynskov, Martin
name: Soeiro, Diana
name: Meszaros, Sophie
Publisher: name: Zenodo
Year: 2025

description: On Thursday, 8 May 2025 (13:00-15:00 CEST), HSbooster.eu co-hosted with Open & Agile Smart Cities (OASC) a webinar on the latest advancements in regulation, innovation, and standards for data sharing and interoperability.

Titled "Europe's Digital Future - Standards and Innovation in Data Spaces" the event brought together key experts to explore how data spaces will transform Europe's digital landscape.

In this document you will find all the presentations delivered by the panellists. 

Learn more on the event page: https://hsbooster.eu/events/europes-digital-future-standards-and-innovation-data-spaces
1-047-Condensation-ModelingScenario
Creators: name: McCarthy, Chris
name: Winkel, Brian
Publisher: name: QUBES Educational Resources
Year: 2022

description: We simulate the random motion of 200 particles in a 50 by 50 square in which a particle bounces off the two vertical and top walls and condenses on the bottom wall. Animations are produced and data is offered for modeling with a differential equation.
A qualitative exploration of cardboard architecture in post-pandemic schools
Creators: name: Deed, Craig
name: Cardellino, P
name: Matthews, E
name: Southall, Anne
Publisher: name: La Trobe
Year: 2022
Subjects: classificationCode: 39
subject: Education
classificationCode: 3901
subject: Curriculum and pedagogy
classificationCode: 3904
subject: Specialist studies in education

description: Governments have responded to the COVID-19 pandemic with social distancing measures, school closures and society lockdowns. The disruption in the functioning of schools have evoked a myriad of emotions among students including the pervasive fear of others and anxiety about a virus that cannot be controlled. As schools reopen, one immediate focus is to ensure proper sanitary measures in classrooms. While important, it is also equally critical that schools effectively support students’ transition back to the classroom environment. This paper considers how cardboard architecture may support transitions between remote home learning and formal school-based education. We use a case study of the Unboxy project, a kit of cardboard shapes and connectors, provided to 18 schools in Australia following the school reopening after covid lockdown. The case study reports a qualitative analysis of how a cardboard architecture project aided students’ transition back to school. Key themes revealed that students created safety structures and spaces for collaboration, thus highlighting the processes with which students interacted with spatial materials to narrate their affective response during the pandemic. Drawing on both research literature and our case study we identify design features of future cardboard architecture resources that can influence student wellbeing upon return to school.