Phylogenomics reveals a complex evolutionary history of Fabaceae NLR immune receptors
Creators: name: Marques, Rita Maravilha Leitão
name: Santos, Carmen
name: Patto, Carlota Vaz
name: Kamoun, Sophien
name: Kourelis, Jiorgos
Publisher: name: Zenodo
Year: 2021
Subjects: Fabaceae
Resistance genes
Nucleotide-binding Leucine-rich Repeat immune receptors
Phylogenomics

description: The legume family (Fabaceae) is the third-largest angiosperm family and is considered one of the most important crop families. Biotic stress constrains legume yield, and resistance gene breeding is currently considered the most sustainable management method to deal with pathogen pressure in the field. Many legumes share the same pathogens, but <strong>whether they share the same resistance genetic basis is currently unknown</strong>. To address this question, <strong>our initial goal was to identify resistance (<em>R</em>) genes in the Fabaceae family</strong>. As a first step towards uncovering the Fabaceae resistance genes repertoire, we undertook a <strong>phylogenomic analysis of nucleotide-binding leucine-rich repeat proteins (NLRs) in 23 legume species.</strong> These analyses <strong>uncovered</strong> <strong>large variations in overall NLR abundance as well as in the distribution of the different NLR classes</strong>. The distribution of the NLR classes did not always match the species phylogeny. For instance, pea (<em>Pisum sativum</em>) and grass pea (<em>Lathyrus sativus</em>) have significantly different NLR repertoires, despite being closely related. The <strong>Fabaceae NLR repertoire</strong> will be an <strong>important tool</strong> for <strong>comparative resistance mapping studies</strong> and for <strong><em>R</em> gene enriched Genome-Wide Association Studies</strong>. The outcome of these analyses will be used to accomplish the long-term goal of my project: to develop tools to assist legume breeding programs for durable resistance.
description: This poster was developed for the British Society for Plant Pathology conference: BSPP2021 - Our Plants, Our Future held on the 6-8th December 2021 at Edgbaston Conference Centre, University of Birmingham, UK. Most genomes were obtained from the publically available Legume Information System (LIS) Data Store.
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