cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Measurement of W$^\pmγ$ differential cross sections in proton-proton collisions at $\sqrt{s}$ = 13 TeV and effective field theory constraints
Creators: name: CMS Collaboration
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Differential cross section measurements of W$^\pmγ$ production in proton-proton collisions at $\sqrt{s}$ = 13 TeV are presented. The data set used in this study was collected with the CMS detector at the CERN LHC in 2016-2018 with an integrated luminosity of 138 fb$^{-1}$. Candidate events containing an electron or muon, a photon, and missing transverse momentum are selected. The measurements are compared with standard model predictions computed at next-to-leading and next-to-next-to-leading orders in perturbative quantum chromodynamics. Constraints on the presence of TeV-scale new physics affecting the WW$γ$ vertex are determined within an effective field theory framework, focusing on the $\mathcal{O}_\mathrm{3W}$ operator. A simultaneous measurement of the photon transverse momentum and the azimuthal angle of the charged lepton in a special reference frame is performed. This two-dimensional approach provides up to a factor of ten more sensitivity to the interference between the standard model and the $\mathcal{O}_\mathrm{3W}$ contribution than using the transverse momentum alone.
description: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables, including additional supplementary figures, can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/SMP-20-005 (CMS Public Pages)
Etablierung eines kooperativen Forschungsdatenmanagements in der U Bremen Research Alliance : Whitepaper
Creators: name: (:Unkn) Unknown
Publisher: name: Universität Bremen
Year: 2021
Subjects: subject: Forschungsdatenmanagement
subject: 80

description: Die U Bremen Research Alliance ist Kernbereich der Bremer Wissenschaft. Sie steht für Kooperation auf den Ebenen Forschung, wissenschaftlicher Nachwuchs, Rekrutierung und Infrastruktur. Um kooperative zukunftsorientierte Wissenschaft zu stärken, verfolgt sie gemeinschaftlich die Schaffung eines abgestimmten Raumes für Innovation, Infrastruktur und Forschung. Die Bereiche Forschungsdatenmanagement, Data Science und Digitalisierung bilden einen Schwerpunkt der Arbeit der Mitglieder der U Bremen Research Alliance. Beispiele dieser Entwicklung sind der Bremer Leibniz-WissenschaftsCampus „Digital Public Health“, die Gründung des Data Science Centers (DSC) an der Universität Bremen, der Aufbau der interdisziplinär und interorganisational getragenen Doktorand*innenausbildung „Data Train – Training in Research Data Management and Data Science“ und die aktive Beteiligung der Mitglieder an vier der neun im Juni 2020 ausgewählten Vorhaben zum Aufbau einer Nationalen Forschungsdateninfrastruktur (NFDI). Bremen ist damit im bundesweiten Vergleich einer der erfolgreichsten NFDI-Standorte. Dieses Whitepaper skizziert den aktuellen Status sowie Handlungsfelder für die disziplinübergreifende Eta- blierung eines kooperativen Forschungsdatenmanagements in der U Bremen Research Alliance.
Forward physics with proton tagging at the LHC
Creators: name: Royon, Christophe
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present some inclusive and exclusive diffractive processes to be studied at the LHC, namely QCD, quartic anomalous couplings between $γ$ and $W/Z$ bosons and diffractive Higgs processes.
description: International Workshop On Discovery Physics at the LHC, Kruger 2012, December 3 - 7, 2012, South Africa
Polybaric fractional crystallisation of arc magmas: an experimental study simulating trans-crustal magmatic systems
Creators: name: Marxer, Felix
name: Ulmer, Peter
name: Müntener, Othmar
Publisher: name: Berlin ; Heidelberg : Springer
Year: 2022
Subjects: subject: Arc magmatism
subject: Calc-alkaline rocks
subject: Fractional crystallisation
subject: Liquid line of descent
subject: Magma differentiation
subject: Polybaric differentiation
subject: calc alkaline rock
subject: clinopyroxene
subject: fractional crystallization
subject: fugacity
subject: magma
subject: time series analysis
subject: trajectory
subject: trend analysis
subject: Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaften

description: Crystallisation-driven differentiation is one fundamental mechanism proposed to control the compositional evolution of magmas. In this experimental study, we simulated polybaric fractional crystallisation of mantle-derived arc magmas. Various pressure–temperature trajectories were explored to cover a range of potential magma ascent paths and to investigate the role of decompression on phase equilibria and liquid lines of descent (LLD). Fractional crystallisation was approached in a step-wise manner by repetitively synthesising new starting materials chemically corresponding to liquids formed in previous runs. Experiments were performed at temperatures ranging from 1140 to 870 °C with 30 °C steps, and pressure was varied between 0.8 and 0.2 GPa with 0.2 GPa steps. For most fractionation paths, oxygen fugacity (fO2) was buffered close to the Ni-NiO equilibrium (NNO). An additional fractionation series was conducted at fO2 corresponding to the Re-ReO2 buffer (RRO ≈ NNO+2). High-pressure experiments (0.4–0.8 GPa) were run in piston cylinder apparatus while 0.2 GPa runs were conducted in externally heated pressure vessels. Resulting liquid lines of descent follow calc-alkaline differentiation trends where the onset of pronounced silica enrichment coincides with the saturation of amphibole and/or Fe–Ti–oxide. Both pressure and fO2 exert crucial control on the stability fields of olivine, pyroxene, amphibole, plagioclase, and Fe–Ti–oxide phases and on the differentiation behaviour of arc magmas. Key observations are a shift of the olivine–clinopyroxene cotectic towards more clinopyroxene-rich liquid composition, an expansion of the plagioclase stability field and a decrease of amphibole stability with decreasing pressure. Decompression-dominated ascent trajectories result in liquid lines of descent approaching the metaluminous compositional range observed for typical arc volcanic rocks, while differentiation trends obtained for cooling-dominated trajectories evolve to peraluminous compositions, similar to isobaric liquid lines of descent at elevated pressures. Experiments buffered at RRO provide a closer match with natural calc-alkaline differentiation trends compared to fO2 conditions close to NNO. We conclude that decompression-dominated fractionation at oxidising conditions represents one possible scenario for arc magma differentiation. © 2021, The Author(s).
Spectral analysis and slow spreading dynamics on complex networks
Creators: name: Ódor, Géza
Publisher: name: arXiv
Year: 2013
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Populations and Evolution (q-bio.PE)
subject: FOS: Physical sciences
subject: FOS: Biological sciences

description: The Susceptible-Infected-Susceptible (SIS) model is one of the simplest memoryless system for describing information/epidemic spreading phenomena with competing creation and spontaneous annihilation reactions. The effect of quenched disorder on the dynamical behavior has recently been compared to quenched mean-field (QMF) approximations in scale-free networks. QMF can take into account topological heterogeneity and clustering effects of the activity in the steady state by spectral decomposition analysis of the adjacency matrix. Therefore, it can provide predictions on possible rare-region effects, thus on the occurrence of slow dynamics. I compare QMF results of SIS with simulations on various large dimensional graphs. In particular, I show that for Erd\H os-Rényi graphs this method predicts correctly the epidemic threshold and the rare-region effects. Griffiths Phases emerge if the graph is fragmented or if we apply strong, exponentially suppressing weighting scheme on the edges. The latter model describes the connection time distributions in the face-to-face experiments. In case of generalized Barabási-Albert type of networks with aging connections strong rare-region effects and numerical evidence for Griffiths Phase dynamics are shown.
description: 7 pages, 7 figues, 1 table
Studio portrait of Gegen Tharchin and family
Creators: name: (:Unav)
Publisher: name: Columbia University
Year: 2020
Subjects: Women, Tibetan

description: Gegen Tharchin with his wife, Karma Dechhen, Rigzin Wangpo seated on the front. Son, Sherab Gyamtsho Tharchin (left), and Tshering Norbu (right) in back.
Little Higgs theory confronted with the LHC Higgs data
Creators: name: Han, Xiao-Fang
name: Wang, Lei
name: Yang, Jin Min
name: Zhu, Jingya
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: We confront the little Higgs theory with the LHC Higgs search data (up to 17 fb$^{-1}$ of the combined 7 and 8 TeV run). Considering some typical models, namely the littlest Higgs model (LH), the littlest Higgs model with T-parity (LHT-A and LHT-B) and the simplest little Higgs model (SLH), we scan over the parameter space in the region allowed by current experiments. We find that in these models the inclusive and exclusive (via gluon-gluon fusion) diphoton and $ZZ^*$ signal rates of the Higgs boson are always suppressed and approach to the SM predictions for a large scale $f$. Thus, the $ZZ^*$ signal rate is within the $1σ$ range of the experimental data while the inclusive diphoton signal rate is always outside the $2σ$ range. Especially, in the LHT-A the diphoton signal rate is outside the $3σ$ range of the experimental data for $f < 800$ GeV. We also perform a global $χ^2$ fit to the available LHC and Tevatron Higgs data, and find that these models provide no better global fit to the whole data set (only for some special channels a better fit can be obtained, specially in the LHT-B).
description: 20 pages, 7 figures, 1 table, Higgs data updated, references added
L-amino acid oxidases with specificity for basic L-amino acids in cyanobacteria
Creators: name: Gau, Achim E.
name: Heindl, Achim
name: Nodop, Anke
name: Kahmann, Uwe
name: Pistorius, Elfriede K.
Publisher: name: Berlin : De Gruyter
Year: 2007
Subjects: subject: Cyanobacteria
subject: L-amino acid oxidase
subject: Synechococcus elongatus PCC 6301 and PCC 7942
subject: Cyanobacterium stanieri
subject: Synechococcus
subject: Synechococcus elongatus
subject: Synechococcus elongatus PCC 6301
subject: Synechococcus elongatus PCC 7942
subject: amino acid
subject: amino acid oxidase
subject: arginine
subject: flavine adenine nucleotide
subject: histidine
subject: lysine
subject: ornithine
subject: amino acid sequence
subject: Anabaena variabilis
subject: article
subject: bacterial genome
subject: binding site
subject: classification
subject: Cyanobacterium
subject: enzyme specificity
subject: genetics
subject: kinetics
subject: metabolism
subject: molecular genetics
subject: Nostoc
subject: nucleotide sequence
subject: sequence homology
subject: Amino Acid Sequence
subject: Amino Acids, Basic
subject: Arginine
subject: Binding Sites
subject: Conserved Sequence
subject: Flavin-Adenine Dinucleotide
subject: Genome, Bacterial
subject: Histidine
subject: Kinetics
subject: L-Amino Acid Oxidase
subject: Lysine
subject: Molecular Sequence Data
subject: Ornithine
subject: Sequence Homology, Amino Acid
subject: Substrate Specificity
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: The two closely related fresh water cyanobacteria Synechococcus elongatus PCC 6301 and Synechococcus elongatus PCC 7942 have previously been shown to constitutively express a FAD-containing L-amino acid oxidase with high specificity for basic L-amino acids (L-arginine being the best substrate). In this paper we show that such an enzyme is also present in the fresh water cyanobacterium Synechococcus cedrorum PCC 6908. In addition, an improved evaluation of the nucleotide/amino acid sequence of the L-amino acid oxidase of Synechococcus elongatus PCC 6301 (encoded by the aoxA gene) with respect to the FAD-binding site and a translocation pathway signal sequence will be given. Moreover, the genome sequences of 24 cyanobacteria will be evaluated for the occurrence of an aoxA-similar gene. In the evaluated cyanobacteria 15 genes encoding an L-amino acid oxidase-similar protein will be found.
title: Characterizing an In Vitro Model of Severe Focal Traumatic Brain Injury in Hippocampal Slice Cultures
title: The Effects of Ethanol and Calpain Inhibition by MDL-28170
titleType: Subtitle
Creators: name: Jagielo-Miller, Julia Elaine
Publisher: name: University of Kentucky Libraries
Year: 2019

description: In the United States, 2.8 million people suffer a traumatic brain injury (TBI) annually. Between 25%-50% of TBI injuries happen under alcohol intoxication. It is not understood how alcohol impacts patient outcomes via secondary injury pathways. Secondary injury pathways offer a window for therapeutic interventions, but there has been little success finding effective medications. Slice cultures offer a way to study secondary injury mechanisms in a controlled manner. The transection injury can model excitotoxicy seen following TBI. The current studies examined the effect of alcohol intoxication and withdrawal at the time of injury, and the effect of a calpain inhibitor (MDL-28170) on cell death following a transection injury. Intoxication had no effect on cell death compared to the TBI condition. In the ethanol withdrawal (EWD) study, EWD did not increase cell death following the TBI except at 72 hours. There was no effect of MDL on cell death. The severity of the model may have caused a ceiling effect. Additionally, imaging points may not have been sufficient for proper characterization. Future studies should use a different injury mechanism and other imaging times should be considered.
description: Copyright © Julia Elaine Jagielo-Miller 2019
Propagation of Alfvénic Waves From Corona to Chromosphere and Consequences for Solar Flares
Creators: name: Russell, Alexander J. B.
name: Fletcher, Lyndsay
Publisher: name: arXiv
Year: 2013
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: How do magnetohydrodynamic waves travel from the fully ionized corona, into and through the underlying partially ionized chromosphere, and what are the consequences for solar flares? To address these questions, we have developed a 2-fluid model (of plasma and neutrals) and used it to perform 1D simulations of Alfvén waves in a solar atmosphere with realistic density and temperature structure. Studies of a range of solar features (faculae, plage, penumbra and umbra) show that energy transmission from corona to chromosphere can exceed 20% of incident energy for wave periods of one second or less. Damping of waves in the chromosphere depends strongly on wave frequency: waves with periods 10 seconds or longer pass through the chromosphere with relatively little damping, however, for periods of 1 second or less, a substantial fraction (37%-100%) of wave energy entering the chromosphere is damped by ion-neutral friction in the mid and upper chromosphere, with electron resistivity playing some role in the lower chromosphere and in umbras. We therefore conclude that Alfvénic waves with periods of a few seconds or less are capable of heating the chromosphere during solar flares, and speculate that they could also contribute to electron acceleration or exciting sunquakes.
description: 52 pages, 6 figures, 1 table, accepted for publication in ApJ
Isomeric di-c-glycosylflavones in fig (ficus carica l.)
Creators: name: Siewek, Fred
name: Herrmann, Karl
name: Grotjahn, Lutz
name: Wray, Victor
Publisher: name: Berlin : De Gruyter
Year: 1985
Subjects: subject: Apigenin-di-C-glycosides
subject: Ficus carica
subject: Identification
subject: Isolation
subject: Quantitative Determination
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: Two isomeric C-glycosides of apigenin (ap ig en in -6-C -glucosyl-8-C -arab in o sid e (schaftoside), apigenin-6-C -arabinosyl-8-C -glucoside (isoschaftoside)) were isolated from leaves of Ficus carica with preparative HPLC. The glycosides were identified by UV-, ′H-N M R-, l3C-NMR-sp ectro scopy and FAB-MS. Their concentration in fruits and leaves were determined by gradient HPLC on reversed phase material. © 1985, Walter de Gruyter. All rights reserved.
Speeding chemical reactions by focusing
Creators: name: Lacasta, A. M.
name: Ramirez-Piscina, L.
name: Sancho, J. M.
name: Lindenberg, K.
Publisher: name: arXiv
Year: 2012
Subjects: subject: Chemical Physics (physics.chem-ph)
subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: We present numerical results for a chemical reaction of colloidal particles which are transported by a laminar fluid and are focused by periodic obstacles in such a way that the two components are well mixed and consequently the chemical reaction is speeded up. The roles of the various system parameters (diffusion coefficients, reaction rate, obstacles sizes) are studied. We show that focusing speeds up the reaction from the diffusion limited rate (t to the power -1/2) to very close to the perfect mixing rate, (t to the power -1).
description: 19 pages, 8 figures
Formation of the compact jets in the black hole GX 339-4
Creators: name: Corbel, S.
name: Aussel, H.
name: Broderick, J. W.
name: Chanial, P.
name: Coriat, M.
name: Maury, A. J.
name: Buxton, M.
name: Tzioumis, J. A. Tomsick A.
name: Markoff, S.
name: Rodriguez, J.
name: Bailyn, C.
name: Brocksopp, C.
name: Fender, R.
name: Petrucci, P. O.
name: Cadolle-Bel, M.
name: Calvelo, D.
name: Harvey-Smith, L.
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Galactic black hole binaries produce powerful outflows with emit over almost the entire electromagnetic spectrum. Here, we report the first detection with the Herschel observatory of a variable far-infrared source associated with the compact jets of the black hole transient GX 339-4 during the decay of its recent 2010-2011 outburst, after the transition to the hard state. We also outline the results of very sensitive radio observations conducted with the Australia Telescope Compact Array, along with a series of near-infrared, optical (OIR) and X-ray observations, allowing for the first time the re-ignition of the compact jets to be observed over a wide range of wavelengths. The compact jets first turn on at radio frequencies with an optically thin spectrum that later evolves to optically thick synchrotron emission. An OIR reflare is observed about ten days after the onset of radio and hard X-ray emission, likely reflecting the necessary time to build up enough density, as well as to have acceleration (e.g. through shocks) along an extended region in the jets. The Herschel measurements are consistent with an extrapolation of the radio inverted power-law spectrum, but they highlight a more complex radio to OIR spectral energy distribution for the jets.
description: Accepted for publication in MNRAS Letter, 6 pages, 3 Figures + 1 online Table
title: Investigation of the Molecular Determinants and Extrinsic Factors that Regulate PRMT Product Specificity
Creators: name: Cáceres, Tamar B.
Publisher: name: Utah State University
Year: 2019

description: Protein arginine methylation is an important modification of proteins, involved in many cellular processes. Some examples are transcription, RNA editing, cellular communication, DNA repair, viral replication and chromatin remodeling. In recent years, the significance of protein arginine methyltransferases (PRMTs) in human diseases has been increasingly studied, especially in cardiovascular disease and cancer. Although the importance of these enzymes is recognized, the understanding of how exactly PRMTs function is still limited. Very little information is available to explain how or why any of the different PRMTs interact with other proteins or, what determines where in that protein to place their methyl marks. Adding to this complexity, placing one of the three different methylation marks (products) or the other (mono methyl arginine MMA, asymmetric dimethyl ADMA, or symmetric dimethyl SDMA) on a protein can cause a cell to respond differently. Therefore, if we really want to understand how this family of proteins functions and how to control them, it’s essential that we understand how they achieve their product specificity; this means, how they decide which methyl mark to place on an interacting protein. In order to better understand the product specificity of this family of enzymes, I have been using as a model two Protein arginine methyltransferases that are responsible different methylation marks: PRMT1, which can make both ADMA and MMA and TbPRMT7, which can only make MMA. Using the information that crystal structure of these enzymes provide and what we already know about how PRMT activity is regulated, my aim is to better understand the mechanisms by which these enzymes achieve their product specificity.
Broadband Excitation by Chirped Pulses: Application to Single Electron Spins in Diamond
Creators: name: Niemeyer, I.
name: Shim, J. H.
name: Zhang, J.
name: Suter, D.
name: Taniguchi, T.
name: Teraji, T.
name: Abe, H.
name: Onoda, S.
name: Yamamoto, T.
name: Ohshima, T.
name: Isoya, J.
name: Jelezko, F.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Pulsed excitation of broad spectra requires very high field strengths if monochromatic pulses are used. If the corresponding high power is not available or not desirable, the pulses can be replaced by suitable low-power pulses that distribute the power over a wider bandwidth. As a simple case, we use microwave pulses with a linear frequency chirp. We use these pulses to excite spectra of single NV-centers in a Ramsey experiment. Compared to the conventional Ramsey experiment, our approach increases the bandwidth by at least an order of magnitude. Compared to the conventional ODMR experiment, the chirped Ramsey experiment does not suffer from power broadening and increases the resolution by at least an order of magnitude. As an additional benefit, the chirped Ramsey spectrum contains not only `allowed' single quantum transitions, but also `forbidden' zero- and double quantum transitions, which can be distinguished from the single quantum transitions by phase-shifting the readout pulse with respect to the excitation pulse or by variation of the external magnetic field strength.
description: 13 pages, 7 figures
Interaction of multi-armed spirals in bistable media
Creators: name: He, Ya-feng
name: Ai, Bao-quan
name: Liu, Fu-cheng
Publisher: name: arXiv
Year: 2013
Subjects: subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We study the interaction of both dense and sparse multi-armed spirals in bistable media modeled by equations of FitzHugh-Nagumo type. Dense 1-armed spiral is characterized by its fixed tip. For dense multi-armed spirals, when the initial distance between tips is less than a critical value, the arms collide, connect and disconnect continuously as the spirals rotate. The continuous reconstruction between the front and the back drives the tips to corotate along a rough circle and to meander zigzaggedly. The rotation frequency of tip, the frequency of zigzagged displacement, the frequency of spiral, the oscillation frequency of media, and the number of arms satisfy certain relations as long as the control parameters of the model are fixed. When the initial distance between tips is larger than the critical value, the behaviors of individual arms within either dense or sparse multi-armed spirals are identical to that of corresponding 1-armed spirals.
description: 18 pages, 9 figures
Organizational attractiveness after identity threats of crises: how potential employees anticipate social identity
Creators: name: Onken-Menke, Greta
name: Lauritzen, Ghita Dragsdahl
name: Nüesch, Stephan
name: Foege, Johann Nils
Publisher: name: London [u.a.] : Taylor & Francis
Year: 2021
Subjects: subject: anticipated organizational identity
subject: Identity threats
subject: organizational attractiveness
subject: organizational crises
subject: signalling theory
subject: social identity theory
subject: Dewey Decimal Classification::100 | Philosophie::150 | Psychologie

description: This study examines how organizations shape potential employees’ social identity prior to joining the organization. This is relevant in light of growing demands for knowledge workers together with a lack of knowledge about the determinants of employer attractiveness for this group. Our study uses different organizational crises as identity-threatening events and extends current research by showing how such events influence potential employees’ anticipations about social identity, as well as their perceptions of the organization’s attractiveness. Empirical evidence from our scenario-based experiments in the United Kingdom and the United States shows that identity changes occurring from organizational crises reduce organizational attractiveness and that anticipated self-continuity and anticipated self-esteem mediate this relationship. The effects become stronger with increasing crisis responsibility. More surprisingly, our qualitative data indicate that certain forms of crises can also attract certain types of employees by triggering organizational compassion, engagement to help the organization recover, and beliefs in learning and future improvements. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
title: Investigation of Protein Dynamics and Communication in Adomet-Dependent Methyltransferases: Non-Ribosomal Peptide Synthetase and Protein Arginine Methyltransferase
Creators: name: May, Kyle M.
Publisher: name: Utah State University
Year: 2019

description: For many enzymes to function correctly they must have the freedom to display a level of dynamics or communication during their catalytic cycle. The effects that protein dynamics and communication can have are wide ranging, from changes in substrate specificity or product profiles, to speed of reaction or switching activity on or off. This project investigates the protein dynamics and communication in two separate systems, a non-ribosomal peptide synthetase (NRPS), and a protein arginine methyltransferase (PRMT).

PRMT1, the enzyme responsible for 80% of arginine methylation in humans, has been implicated in a variety of disease states when functioning incorrectly. For this reason, much focus has been placed on better understanding how PRMT1 determines which products it creates and at what times. This project aims to shed light on how dynamics and communication within PRMT1 dictate its activity. We have to this point developed a protocol for creating and purifying a linked PRMT1 construct which will enable us to conduct the necessary experiments capable of answering our larger questions about the PRMT1 catalytic mechanism.

Our collaborators in the Zhan lab discovered the presence of a methyltransferase (Mt) in the two NRPS systems they study, which produce two different and medically relevant compounds, bassianolide and beauvericin. The Hevel lab is well suited to study methyltransferases and so were asked to help evaluate the role of these Mt domains and how they affect the production of the relevant natural products. Achieving a more complete understanding of these systems will move us closer toward the “holy grail” of being able to manipulate and harness NRPS systems for the engineering of novel medically relevant compounds. This project has found that the Mt domain substrate specificity is affected by the surrounding protein domains, or even small portions of them.
Localized modes in dense repulsive and attractive Bose-Einstein condensates with spin-orbit and Rabi couplings
Creators: name: Salasnich, Luca
name: Malomed, Boris A.
Publisher: name: arXiv
Year: 2013
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Pattern Formation and Solitons (nlin.PS)
subject: FOS: Physical sciences

description: We consider a binary Bose-Einstein condensate with linear and nonlinear interactions between its components, which emulate the spinor system with spin-orbit (SO) and Rabi couplings. For a relatively dense condensate, 1D coupled equations with the nonpolynomial nonlinearity of both repulsive and attractive signs are derived from the 3D Gross-Pitaevskii equations. Profiles of modes confined in an external potential under the action of the self-repulsion, and self-trapped solitons in the case of the self-attraction, are found in a numerical form and by means of analytical approximations. In the former case, the interplay of the SO and Rabi couplings with the repulsive nonlinearity strongly distorts shapes of the trapped modes, adding conspicuous side lobes to them. In the case of the attractive nonlinearity, the most essential result is reduction of the collapse threshold under the action of the SO and Rabi couplings.
description: 7 pages, 5 figures, to be published in Phys. Rev. A
title: Physiological, Behavioral, and Self-Report Outcomes of Acceptance and Regulation Approaches to Exposures for Intrusive Thoughts
Creators: name: Smith, Brooke M.
Publisher: name: Utah State University
Year: 2019

description: Cognitive-behavioral therapy that includes exposure, or intentionally and systematically confronting feared situations, is the gold standard psychological treatment for obsessive-compulsive disorder. However, less than half of those who begin this treatment are considered to have recovered from their disorder at the end of treatment, and this number is even smaller in the months following the end of treatment. Leading theories regarding how treatment changes occur focus on reducing fear, and they do not include “voluntary” (i.e., operant) behaviors, such as avoidance, that are key features of the disorder. Acceptance-based approaches to exposure do not focus on fear reduction, but directly focus on changing “voluntary” behaviors. Combining these two perspectives could lead to a better understanding of how exposure works and, ultimately, lead to more effective and long-lasting psychological treatments for obsessive-compulsive disorder.

The current study investigated whether accepting distress or attempting to reduce distress during exposure for intrusive thoughts led to different outcomes and whether they led to these outcomes in different ways. Participants with intrusive thoughts were randomized to three groups, Acceptance (n = 23), Regulation (n = 20), and Control (n = 21), and completed two sessions 1 week apart. Participants in the Acceptance and Regulation groups completed a 30-minute exposure at session 1 and 6 days of 10-minute exposures at home; Control participants watched videos of the same lengths. Self-report questionnaires, measures of behavior, self-ratings, and physiological data were collected at both sessions.

Results showed that Acceptance and Regulation groups decreased on measures of obsessive-compulsive symptom severity, rituals performed, self-rated distress, and skin conductance levels. Acceptance showed lower skin conductance and a statistical trend toward greater self-rated willingness to experience distress than Regulation, as well as greater psychological flexibility than Control. There were no between group differences in the number of exposure tasks completed during a behavioral test, psychological inflexibility, valued living, or heart rate. This study suggests that psychological flexibility and willingness to experience distress may paradoxically lead to decreased physiological arousal, findings which may inform future research and treatment approaches.
Isolierung und Identifizierung der Flavon(ol)glykoside der Endivien (Cichorium endivia L.) und des Kopfsalates (Lactuca sativa L.)
Creators: name: Wöldecke, M.
name: Herrmann, Karl
Publisher: name: Berlin : De Gruyter
Year: 1974
Subjects: subject: Endives
subject: Kaempferol Glycosides
subject: Lettuce
subject: Luteolin Glucuronide
subject: Quercetin Glycosides
subject: bioflavonoid
subject: glucose
subject: article
subject: capillary permeability
subject: drug effect
subject: human
subject: hydrolysis
subject: inflammation
subject: infrared spectrophotometry
subject: isolation and purification
subject: pH
subject: plant
subject: thin layer chromatography
subject: ultraviolet spectrophotometry
subject: Bioflavonoids
subject: Capillary Permeability
subject: Chromatography, Thin Layer
subject: English Abstract
subject: Glucose
subject: Human
subject: Hydrogen-Ion Concentration
subject: Hydrolysis
subject: Inflammation
subject: Plants, Edible
subject: Spectrophotometry, Infrared
subject: Spectrophotometry, Ultraviolet
subject: Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie

description: For the first time, quercetin-3-β-ᴅ-glucuronide, quercetin-3-β-ᴅ-glucoside, quercetin-3-(O-malonyl) -β-ᴅ-glucoside and luteolin-7-/9-ᴅ-glucuronide were isolated from lettuce and kaempferol-3-β-D-glucuronide and kaempferol-3-β-ᴅ-glucoside from endives as crystals. The flavonol glucuronides are the main glycosides. Moreover a glycoside was found in endives which is very probably identical with kaempferol-3-(O-malonyl) -β-ᴅ-glucoside.
Elektronische Wechselwirkung zwischen aufgedampften Germaniumfilmen und Sauerstoff
Creators: name: Suhrmann, R.
name: Kruel, M.
name: Wedler, G.
Publisher: name: Berlin : De Gruyter
Year: 1963
Subjects: subject: Ge films of thicknesses
subject: p-boundary layer thickness
subject: ultra high vacuum
subject: Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik

description: Ge films of thicknesses within the p-boundary layer thickness are precipitated under ultra high vacuum conditions, at 77 °K. They are investigated either in the disordered state (before annealing at a higher temperature) or in the ordered state (after annealing). The electric resistance R and the photoelectric work function & are measured before and after the influence of known amounts of oxygen. R is plotted as a function of time and coverage n, Φ as a function of n. Small amounts of oxygen cause R to increase without changing Φ, large amounts result in a succeeding decrease of R and cause Φ to increase by 0.1 to 0.2 V. The results are discussed by means of a band model. At small coverages oxygen acts as an electron donator, at higher coverages as an electron acceptor. © 1963, Walter de Gruyter. All rights reserved.
Supersymmetric Proca-Yang-Mills System
Creators: name: Sezgin, Ergin
name: Wulff, Linus
Publisher: name: arXiv
Year: 2012
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We determine the off-shell N=1 supersymmetry transformation rules for a tensor-Yang-Mills system in which the tensor field transforms in a nontrivial representation of the Yang-Mills group, and there is an additional vector multiplet in the same representation. We then show that this system describes a massive tensor multiplet coupled to Yang-Mills in which the additional vector multiplet is eaten by the tensor field. Next, we construct an action which consists of four separately off-shell supersymmetric pieces and find that integrating out the auxiliary fields gives rise to an infinite number of higher order couplings of the scalar field belonging to the tensor multiplet. We describe the dualization of the massive tensor to a massive vector, thereby ending up with an on-shell supersymmetric nonabelian massive vector multiplet coupled to an off-shell Yang-Mills multiplet which we refer to as the supersymmetric Proca-Yang-Mills system. This description of massive vectors is contrasted with the standard one obtained through the Higgs mechanism.
description: 19 pages
Dynamic and Static Suitability Mapping: Suitability of sustainable land practices in Central and West Asia based on biophysical criteria and global hydrological modelling
Creators: name: Van der Haar, Erwin
name: Haddad, Mira
name: de Jong, Steven
Publisher: name: figshare
Year: 2023
Subjects: Physical geography and environmental geoscience not elsewhere classified

description: The dynamic and static suitability of three sustainable land management (SLM) practices were determined for different parts of Central and West Asia. The research focussed on two rainwater harvesting (RWH) structures and one other SLM as well as combining them: Marab, “Vallerani”, Saxaul tree plantations and the combination of these. All three SLMs were evaluated for the static suitability and the two RWH structures were evaluated for the dynamic suitability. The static suitability mapping consisted of evaluating the suitability of several biophysical criteria in Uzbekistan and resulted in high suitability of all 3 types. Especially the “Vallerni” type, followed by the Marab and the Saxaul Tree plantations. The combination of multiple SLMs on one location also resulted in high suitability in Uzbekistan. The reason for the high suitability were the broad ranges of the biophysical criteria chosen. To increase accuracy of results, narrower specifications are needed for the SLMs. The dynamic suitability was performed based on runoff generation as modelled by the PCR-GLOBWB 2, a grid-based global hydrology and water resource model, which was run for most of Central and West Asia. The dynamics suitability was based the three following criteria: sufficient annual rainfall to fill the structures, multiple fillings per year, and low variability between years. The results showed underestimations of runoff when compared to observed runoff. Furthermore, for regions where the first two criteria were true and high enough runoff was reported, the variability often was high resulting in very few regions with dynamic suitability and the method is better suited as a framework than as real suitability of RWH in the study area. Discrepancy of observed and modelled runoff is likely due to poor model parameterization, with small scale rainfall-runoff generation not properly occurring. Furthermore, input data could be improved, and model resolution increased to yield better results in future. Overall, static and dynamic suitability could not be compared due to the different results of the methods used.
Modelling short- and long-term dependencies of clustered high-threshold exceedances in significant wave heights
Creators: name: Dissanayake, Pushpa
name: Flock, Teresa
name: Meier, Johanna
name: Sibbertsen, Philipp
Publisher: name: Basel : MDPI AG
Year: 2021
Subjects: subject: ARFIMA models
subject: Extremal clustering
subject: Extreme value theory
subject: Long-range dependence
subject: Peaks-over-threshold
subject: Sefton coast
subject: Significant wave heights
subject: Dewey Decimal Classification::500 | Naturwissenschaften::510 | Mathematik

description: The peaks-over-threshold (POT) method has a long tradition in modelling extremes in environmental variables. However, it has originally been introduced under the assumption of independently and identically distributed (iid) data. Since environmental data often exhibits a time series structure, this assumption is likely to be violated due to short-and long-term dependencies in practical settings, leading to clustering of high-threshold exceedances. In this paper, we first review popular approaches that either focus on modelling short-or long-range dynamics explicitly. In particular, we consider conditional POT variants and the Mittag–Leffler distribution modelling waiting times between exceedances. Further, we propose a new two-step approach capturing both short-and long-range correlations simultaneously. We suggest the autoregressive fractionally integrated moving average peaks-over-threshold (ARFIMA-POT) approach, which in a first step fits an ARFIMA model to the original series and then in a second step utilises a classical POT model for the residuals. Applying these models to an oceanographic time series of significant wave heights measured on the Sefton coast (UK), we find that neither solely modelling short-nor long-range dependencies satisfactorily explains the clustering of extremes. The ARFIMA-POT approach, however, provides a significant improvement in terms of model fit, underlining the need for models that jointly incorporate short-and long-range dependence to address extremal clustering, and their theoretical justification. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
title: Vor Kindle: Die Anfänge des E-Books
Creators: name: Jungbluth, Anja
Publisher: name: University Library Heidelberg
Year: 2015

description: E-Books gewinnen in Bibliotheken immer stärker an Bedeutung. In Bezug auf Erwerbung, Einarbeitung und Benutzung gibt es bei E-Books im Vergleich zu klassischen Print-Büchern allerdings große Unterschiede, von denen einige in diesem Artikel erläutert werden. Grundlegende technische Enwicklungen, die bei der Verbreitung der eletronischen Bücher eine wichtige Rolle gespielt haben, darunter historische und heute übliche Dateiformate sowie eine Übersicht über die ersten Lesegeräte bis hin zum Kindle, mit dem der E-Book-Reader den Durchbruch auf dem Mainstream-Markt schaffte, werden vorgestellt. Ein kurzer Überblick über drei wichtige Problemfelder, mit denen gerade Bibliotheken im Zusammenhang mit der steigenden Verbreitung von E-Books zu kämpfen haben (Lizenzierung, Kosten und Datenschutz), rundet den Beitrag ab.
description: Perspektive Bibliothek, Bd. 4, Nr. 2 (2015), Beginn und Erscheinungsfrequenz: Nummer: 1, Jahr: 2012, Bände pro Jahr: 1
Chandra observation of the Galactic supernova remnant CTB 109 (G109.1-1.0)
Creators: name: Sasaki, Manami
name: Plucinsky, Paul P.
name: Gaetz, Terrance J.
name: Bocchino, Fabrizio
Publisher: name: arXiv
Year: 2013
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: Context: We study the X-ray emission of the Galactic supernova remnant (SNR) CTB 109 (G109.1-1.0), which is well-known for its enigmatic half-shell morphology both in radio and in X-rays and is associated with the anomalous X-ray pulsar (AXP) 1E2259+586. Aims: We want to understand the origin of the X-ray bright feature inside the SNR called the Lobe and the details of the interaction of the SNR shock wave with the ambient interstellar medium (ISM). Methods: The Lobe and the northeastern part of the SNR were observed with Chandra ACIS-I. We analysed the spectrum of the X-ray emission by dividing the entire observed emission into small regions. The X-ray emission is best reproduced with one-component or two-component non-equilibrium ionisation models depending on the position. In the two-component model one emission component represents the shocked ISM and the other the shocked ejecta. Results: We detect enhanced element abundances, in particular for Si and Fe, in and around the Lobe. There is one particular region next to the Lobe with a high Si abundance of 3.3 (2.6 - 4.0) times the solar value. This is the first, unequivocal detection of ejecta in CTB 109. Conclusions: The new Chandra data confirm that the Lobe was created by the interaction of the SNR shock and the supernova ejecta with dense and inhomogeneous medium in the environment of SNR CTB 109. The newly calculated age of the SNR is t ~ 1.4 x 10^4 yr.
description: Accepted for publication in A&A. 9 pages, 10 figures
Distributed Intrusion Detection of Byzantine Attacks in Wireless Networks with Random Linear Network Coding
Creators: name: Chen, Jen-Yeu
name: Tseng, Yi-ying
Publisher: name: arXiv
Year: 2013
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: Network coding is an elegant technique where, instead of simply relaying the packets of information they receive, the nodes of a network are allowed to combine \emph{several} packets together for transmission and this technique can be used to achieve the maximum possible information flow in a network and save the needed number of packet transmissions. Moreover, in an energy-constraint wireless network such as Wireless Sensor Network (a typical type of wireless ad hoc network), applying network coding to reduce the number of wireless transmissions can also prolong the life time of sensor nodes. Although applying network coding in a wireless sensor network is obviously beneficial, due to the operation that one transmitting information is actually combination of multiple other information, it is possible that an error propagation may occur in the network. This special characteristic also exposes network coding system to a wide range of error attacks, especially Byzantine attacks. When some adversary nodes generate error data in the network with network coding, those erroneous information will be mixed at intermeidate nodes and thus corrupt all the information reaching a destination. Recent research efforts have shown that network coding can be combined with classical error control codes and cryptography for secure communication or misbehavior detection. Nevertheless, when it comes to Byzantine attacks, these results have limited effect. In fact, unless we find out those adversary nodes and isolate them, network coding may perform much worse than pure routing in the presence of malicious nodes. In this paper, a distributed hierarchical algorithm based on random linear network coding is developed to detect, locate and isolate malicious nodes.
Komplexe Trithiocarbonate des zweiwertigen Kobalts
Creators: name: Bruhn, A.
name: Seidel, H.
Publisher: name: Berlin : De Gruyter
Year: 1974
Subjects: subject: cobalt
subject: Complex
subject: trithiocarbonates
subject: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie

description: Läßt man bei Raumtemperatur unter Sauerstoffausschluß CS2 über die Gasphase in eine NH3-gesättigte wäßrige Lösung von [Co(NH3)6Cl2 diffundieren, dann bilden sich im Verlaufe von 24 Stdn. blauschwarze glänzende Rhomboeder und Kristallnadeln. Ihre analytisch gefundene Zusammensetzung ist Co(NH3)3CS3.