cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Investigating PYY3-36 and PYY3-36 analogues in the development of an obesity therapy
Creators: name: Addison, Melisande L.
Publisher: name: Imperial College London
Year: 2010

description: Obesity, defined as a body mass index greater than 30kg/m2, has reached the scale of a pandemic. The increasing prevalence of obesity, and its associated morbidity and mortality, together with limited treatment options, underscores an urgent need for effective therapeutic interventions. Gut hormones have been identified as integral factors in the regulation of appetite. One such gut hormone is Peptide YY (PYY), a postprandial satiety hormone that communicates nutritional status to the central nervous system. PYY is processed to generate the principle circulating form PYY3-36, which acts on Y2 receptors in the brainstem and hypothalamus to reduce appetite. Chronic intravenous infusion of PYY3-36 induces weight loss in rodents and acute intravenous infusion to obese humans reduces food intake. Furthermore, obese humans have been reported to display a blunted postprandial rise in PYY3-36, suggesting PYY3-36 is a potential anti-obesity drug target. However, exogenous PYY3-36 is rapidly cleared and has a short circulating half-life. Additionally, at supraphysiological levels PYY3-36 can produce nausea in humans. The administration of long-acting PYY3-36 analogues to the obese may overcome these limitations. This thesis investigates the design and development of PYY3-36 analogues, and their potential in the treatment of obesity. I have investigated modifications to different domains within the primary structure of PYY3-36 in order to elucidate Y2R affinity, susceptibility to proteolytic degradation and biological activity. I demonstrated that a combination of substitutions in different domains can create a long acting analogue. I have examined sites at which PYY3-36 is susceptible to degradation by specific proteases and identified that inhibition of meprin metalloendopeptidases can prolong the plasma longevity and anorectic actions of PYY3-36. I also found that substitution of a section of the α-helix of PYY3-36 with a conserved α-helical epitope creates a long-acting analogue, that is more efficacious than PYY3-36 in chronically reducing food intake and body weight in a diet-induced obese rodent model. Finally, in investigating a slow-release delivery system for PYY3-36 analogues, I have shown that substituting His residues into the α-helix-substituted analogue promotes chelation with Zn in vitro, and facilitates a slow-release pharmacokinetic profile in vivo, that may circumvent the side effects associated with administering high levels of PYY3-36.
On the sine-Gordon--Thirring equivalence in the presence of a boundary
Creators: name: Sheng, Z-M
name: Gao, H-B
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, the relationship between the sine-Gordon model with an integrable boundary condition and the Thirring model with boundary is discussed and the reflection $R$-matrix for the massive Thirring model, which is related to the physical boundary parameters of the sine-Gordon model, is given. The relationship between the the boundary parameters and the two formal parameters appearing in the work of Ghoshal and Zamolodchikov is discussed.
description: 14 pages, Latex, to be published in Int. J. Mod. Phys. A. Two references added
First principles modelling of dislocations in BCC iron
Creators: name: Soin, Preetma Kaur
Publisher: name: Imperial College London
Year: 2012

description: This work centers around employing magnetic tight binding to study defects in body centred cubic iron, a material of potentially great importance as a structural component in hydrogen fusion power plants. An existing d-band tight binding model was extended to include charge. The first task was to develop a working scheme for calculating spins and charges self consistently. This was achieved using an extended form of the Harris-Foulkes functional and implemented with a generalisation of the Newton-Raphson minimisation procedure. Having established such a scheme it was tested on bulk structures, point defects and straight dislocations. The motion of dislocations and the opposition to this was also considered though calculation of Peierls barriers.
Emission lines due to ionizing radiation from a compact object in the remnant of Supernova 1987A
Creators: name: Fransson, C.
name: Barlow, M. J.
name: Kavanagh, P. J.
name: Larsson, J.
name: Jones, O. C.
name: Sargent, B.
name: Meixner, M.
name: Bouchet, P.
name: Temim, T.
name: Wright, G. S.
name: Blommaert, J. A. D. L.
name: Habel, N.
name: Hirschauer, A. S.
name: Hjorth, J.
name: Lenkić, L.
name: Tikkanen, T.
name: Wesson, R.
name: Coulais, A.
name: Fox, O. D.
name: Gastaud, R.
name: Glasse, A.
name: Jaspers, J.
name: Krause, O.
name: Lau, R. M.
name: Nayak, O.
name: Rest, A.
name: Colina, L.
name: van Dishoeck, E. F.
name: Gudel, M.
name: Henning, Th.
name: Lagage, P. -O.
name: Őstlin, G.
name: Ray, T. P.
name: Vandenbussche, B.
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The nearby Supernova 1987A was accompanied by a burst of neutrino emission, which indicates that a compact object (a neutron star or black hole) was formed in the explosion. There has been no direct observation of this compact object. In this work, we observe the supernova remnant with JWST spectroscopy finding narrow infrared emission lines of argon and sulphur. The line emission is spatially unresolved and blueshifted in velocity relative to the supernova rest frame. We interpret the lines as gas illuminated by a source of ionizing photons located close to the center of the expanding ejecta. Photoionization models show that the line ratios are consistent with ionization by a cooling neutron star or pulsar wind nebula. The velocity shift could be evidence for a neutron star natal kick.
description: Authors version of manuscript published in Science on 22 Feb 2024
A Remark on the Estimation of Angular Power Spectra in the Presence of Foregrounds
Creators: name: White, Martin
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: It is common practice to estimate the errors on the angular power spectrum which could be obtained by an experiment with a given angular resolution and noise level. Several authors have also addressed the question of foreground subtraction using multi-frequency observations. In such observations the angular resolution of the different frequency channels is rarely the same. In this report we point out how the ``effective'' beam size and noise level change with ell in this case, and give an expression for the error on the angular power spectrum as a function of ell.
description: 3 pages, no figures, to appear in Phys Rev D
Comparison of Deep Learning Techniques on Human Activity Recognition using Ankle Inertial Signals
Creators: name: Nazari, Farhad
name: Nahavandi, Darius
name: Mohajer, Navid
name: Khosravi, Abbas
Publisher: name: arXiv
Year: 2024
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: FOS: Computer and information sciences

description: Human Activity Recognition (HAR) is one of the fundamental building blocks of human assistive devices like orthoses and exoskeletons. There are different approaches to HAR depending on the application. Numerous studies have been focused on improving them by optimising input data or classification algorithms. However, most of these studies have been focused on applications like security and monitoring, smart devices, the internet of things, etc. On the other hand, HAR can help adjust and control wearable assistive devices, yet there has not been enough research facilitating its implementation. In this study, we propose several models to predict four activities from inertial sensors located in the ankle area of a lower-leg assistive device user. This choice is because they do not need to be attached to the user's skin and can be directly implemented inside the control unit of the device. The proposed models are based on Artificial Neural Networks and could achieve up to 92.8% average classification accuracy
description: This is the accepted version of an article published in the proceedings of the 2022 IEEE International Conference on Systems, Man, and Cybernetics (SMC)
A novel genetic variant potentially altering the expression of MANBA in the cerebellum associated with attention deficit hyperactivity disorder in Han Chinese children
Creators: name: Chen, Xinzhen
name: Yao, Ting
name: Cai1, Jinliang
name: Zhang, Qi
name: Li, Shanyawen
name: Li, Huiru
name: Fu, Xihang
name: Wu, Jing
Publisher: name: Taylor & Francis
Year: 2021
Subjects: subject: Medicine
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Neuroscience
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Mental Health

description: To get additional insight into the genetic factors of attention deficit hyperactivity disorder (ADHD). First, we performed a transcriptome-wide association study (TWAS) integrating human cerebellum-specific variant-expression/splicing correlations to identify ADHD susceptibility genes. Then, the associations between expression/splicing quantitative trait loci (eQTLs/sQTLs) of the transcriptome-wide significant genes and ADHD were observed in a case-control study of Han Chinese children. Furthermore, dual luciferase reporter gene assays were performed to validate the regulatory function of ADHD risk variants. Additionally, the transcription level of target genes in blood was detected by real-time quantitative polymerase chain reaction (RT-qPCR) assay. TWAS identified that the genetically regulated expression of MANBA in the cerebellum was significantly associated with ADHD risk. Furthermore, we observed a higher risk of ADHD and more severe clinical symptoms in subjects harbouring heterozygous (TC) or mutant homozygous (TT) genotypes of MANBA rs1054037 than CC carriers. The dual luciferase reporter gene assay revealed that the mutation of rs1054037(C > T) potentially upregulated MANBA expression by eliminating the binding site for hsa-miR-5591-3P. Finally, RT-qPCR showed that MANBA expression in blood samples of patients was significantly higher than that of controls. Taken together, these results suggest a role of MANBA in the development of ADHD.
Tenthredo pratensis Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Tenthredo
Tenthredo pratensis

description: Tenthredo pratensis [spec. nov.]
T. antennis septemnodiis, corpore nigro, abdominis segmentis quatuor ferrugineis. Fn. svec. 928.
Frisch. ins. 2. t. 1. f. 21-24.
Habitat in Europa.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 556, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
title: ADCO, Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Cart. 192 (11 H 77), 295 folios, f. 0292r
Creators: name: de la Côte d'Or, Archives départementales
name: Petot, Frédéric
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CG21/F.PETOT/2012
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris
subject: cartulaire

description: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0292r, Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Cartulaire général de Cîteaux, dit de Jean de Cirey, (XVe siècle), tome VIII, Archives départementales de la Côte-d'Or, Cart. 192 (11 H 77), 295 folios, f. 0292r, in Projet CBMA - Corpus Burgundiae Medii Aevi [Ressource en ligne], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Resistively-limited current sheet implosions in planar anti-parallel (1D) and null-point containing (2D) magnetic field geometries
Creators: name: Thurgood, J. O.
name: Pontin, D. I.
name: McLaughlin, J. A.
Publisher: name: arXiv
Year: 2018
Subjects: subject: Plasma Physics (physics.plasm-ph)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: Implosive formation of current sheets is a fundamental plasma process. Previous studies focused on the early time evolution, while here our primary aim is to explore the longer-term evolution, which may be critical for determining the efficiency of energy release. To address this problem we investigate two closely-related problems, namely: (i) 1D, pinched anti-parallel magnetic fields and (ii) 2D, null point containing fields which are locally imbalanced ('null-collapse' or 'X-point collapse'). Within the framework of resistive MHD, we simulate the full nonlinear evolution through three distinct phases: the initial implosion, its eventual halting mechanism, and subsequent evolution post-halting. In a parameter study, we find the scaling with resistivity of current sheet properties at the halting time is in good agreement - in both geometries - with that inferred from a known 1D similarity solution. We find that the halting of the implosions occurs rapidly after reaching the diffusion scale by sudden Ohmic heating of the dense plasma within the current sheet, which provides a pressure gradient sufficient to oppose further collapse and decelerate the converging flow. This back-pressure grows to exceed that required for force balance and so the post-implosion evolution is characterised by the consequences of the current sheet `bouncing' outwards. These are: (i) the launching of propagating fast MHD waves (shocks) outwards and (ii) the width-wise expansion of the current sheet itself. The expansion is only observed to stall in the 2D case, where the pressurisation is relieved by outflow in the reconnection jets. In the 2D case, we quantify the maximum amount of current sheet expansion as it scales with resistivity, and analyse the structure of the reconnection region which forms post-expansion, replete with Petschek-type slow shocks and fast termination shocks.
description: Published open access in Physics of Plasmas - go to main journal for animations https://doi.org/10.1063/1.5035489
$π$ Phase Interlayer Shift and Stacking Fault in the Kagome Superconductor CsV$_3$Sb$_5$
Creators: name: Jin, Feng
name: Ren, Wei
name: Tan, Mingshu
name: Xie, Mingtai
name: Lu, Bingru
name: Zhang, Zheng
name: Ji, Jianting
name: Zhang, Qingming
Publisher: name: arXiv
Year: 2024
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: The stacking degree of freedom is a crucial factor in tuning material properties and has been extensively investigated in layered materials. The kagome superconductor CsV$_3$Sb$_5$ was recently discovered to exhibit a three-dimensional CDW phase below TCDW ~94 K. Despite the thorough investigation of in-plane modulation, the out-of-plane modulation has remained ambiguous. Here, our polarization- and temperature-dependent Raman measurements reveal the breaking of C$_6$ rotational symmetry and the presence of three distinct domains oriented at approximately 120°to each other. The observations demonstrate that the CDW phase can be naturally explained as a 2c staggered order phase with adjacent layers exhibiting a relative $π$ phase shift. Further, we discover a first-order structural phase transition at approximately 65 K and suggest that it is a stacking order-disorder phase transition due to stacking fault, supported by the thermal hysteresis behavior of a Cs-related phonon mode. Our findings highlight the significance of the stacking degree of freedom in CsV$_3$Sb$_5$ and offer structural insights to comprehend the entanglement between superconductivity and CDW.
description: This manuscript was published in Phys. Rev. Lett
Quantization of fields over de Sitter space by the method of generalized coherent states
Creators: name: Pol'shin, Semyon
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: A system of generalized coherent states for the de Sitter group obeying the Klein-Gordon equation and corresponding to the massive spin zero particles over the de Sitter space is considered. This allows us to construct the quantized scalar field by the resolution over these coherent states; the corresponding propagator is computed by the method of analytic continuation to the complex de Sitter space and coincides with expressions obtained previously by other methods. Considering the case of spin 1/2 we establish the connection of the invariant Dirac equation over the de Sitter space with irreducible representations of the de Sitter group. The set of solutions of this equation is obtained in the form of the product of two different systems of generalized coherent states for the de Sitter group. Using these solutions the quantized Dirac field over de Sitter space is constructed and its propagator is found. It is a result of action of some de Sitter invariant spinor operator onto the spin zero propagator with an imaginary shift of a mass. We show that the constructed propagators possess the de Sitter-invariance and causality properties.
description: 19 pages, LATEX, using ioplppt.sty and iopfts.sty
p-brane Solitons in Maximal Supergravities
Creators: name: Lu, H.
name: Pope, C. N.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: In this paper, we give a construction of $p$-brane solitons in all maximal supergravity theories in $4\le D \le 11$ dimensions that are obtainable from $D=11$ supergravity by dimensional reduction. We first obtain the full bosonic Lagrangians for all these theories in a formalism adapted to the $p$-brane soliton construction. The solutions that we consider involve one dilaton field and one antisymmetric tensor field strength, which are in general linear combinations of the basic fields of the supergravity theories. We also study the supersymmetry properties of the solutions by calculating the eigenvalues of the Bogomol'nyi matrices, which are derived from the commutators of the supercharges. We give an exhaustive list of the supersymmetric $p$-brane solutions using field strengths of all degrees $n=4,3,2,1$, and the non-supersymmetric solutions for $n=4,3,2$. As well as studying elementary and solitonic solutions, we also discuss dyonic solutions in $D=6$ and $D=4$. In particular, we find that the Bogomol'nyi matrices for the supersymmetric massless dyonic solutions have indefinite signature.
description: 31 pages, Latex, no figures
Galactic Indigestion: Numerical Simulations of the Milky Way's Closest Neighbor
Creators: name: Ibata, Rodrigo
name: Lewis, Geraint
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: Are dwarf spheroidal galaxies dark matter dominated? We present N-body simulations of the interaction between the Milky Way and its closest companion, the Sagittarius dwarf spheroidal galaxy, constrained by new kinematic, distance and surface density observations detailed in a companion paper. It is shown that there is no possible self-consistent solution to the present existence of the Sagittarius dwarf if its distribution of luminous matter traces the underlying distribution of mass. The luminous component of the dwarf galaxy must therefore be shielded within a small dark matter halo. Though at present we are unable to construct a fully self-consistent model that includes both the stellar and dark matter components, it is shown numerically that it is possible that a pure dark matter model, approximating the dark matter halo deduced for the Sagittarius dwarf from analytical arguments, may indeed survive the Galactic tides. The orbit of the Sagittarius dwarf galaxy around the Milky Way is considered, taking into account the perturbative effects of the Magellanic Clouds. It is shown that at the present time, the orbital period must be short, ~ 0.7 Gyr; the initial orbital period for a 10^9 Solar mass model will have been ~ 1 Gyr. It is found that a close encounter with the Magellanic Clouds may have occured, though the chances of such an interaction affecting the orbit of the Sagittarius dwarf galaxy is negligible.
description: To appear in ApJ
Tenthredo cerasi Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Tenthredo
Tenthredo cerasi

description: Tenthredo cerasi [spec. nov.]
T. antennis septemnodiis, corpore nigro, pedibus luteis.
Reaum. ins. 5. t. 12. f. 1-5.
Habitat in Cerasi foliis, quae involvit ut mutetur.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 557, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
Oral history interview with Nestor Granelli 1997
Publisher: name: Columbia University
Year: 2019

description: Childhood, Buenos Aires, Argentina: seafaring family, military education; Argentina’s historical role in geographical exploration; impact of World War II exiles on Argentinean culture, scientific research; mapping and hydrography work with the Argentine Navy Antarctic Task Force, 1953-54; consequences of the 1955 revolution; 1957 Vema cruise collaboration between Lamont Geophysical Observatory, Argentinean Navy: data collection, work ethic, equipment, difficult living conditions; impact of International Geophysical Year on Argentinean science; Soviet scientists during Cold War; continental drift research and debates; studies at Columbia University, 1959-1964; work in Argentina’s Naval Hydrographic office; private hydrographic consulting work; relationship between politics and scientific research in Argentina; reminiscences of colleagues.
Oral history interview with Nelson Trusler Johnson, 1954
Publisher: name: Columbia University
Year: 2021
Subjects: Diplomats--United States

description: Family background and early life; experiences as student interpreter for Consular Service in China, 1907; Battle of the Concessions, Open Door Policy; Manchuria, 1909-1910; concession railways; Taiping rebellion; Revolution of 1911; Yale-in-China activities; Chinese social life and attitudes, early 1900s; recall to Washington and preparations for the Washington Conference; appointment as inspection officer in China, 1923
Embedding individual-based plankton ecosystem models in a finite element ocean model
Creators: name: Lange, Michael
Publisher: name: Imperial College London
Year: 2013

description: Computational models of the ocean plankton ecosystem are traditionally based on simulating entire populations of microbes using sets of coupled differential equations. However, due to recent advances in high-performance computing, a new class of individual-based models (IBM) has come to the fore, which uses computational agents to model individual sub-populations of marine plankton. Although computationally more expensive, these agent-based models offer features that cannot be re-created using population-level dynamics, such as individual life cycles, intra-population variability and an increased stability over parameter ranges. The main focus of this thesis is the implementation and verification of an embedded modelling framework for creating agent-based plankton ecology models in Fluidity-ICOM, a state-of-the-art ocean model that solves the Navier-Stokes equations on adaptive unstructured finite element meshes. Since Fluidity-ICOM provides an interface for creating population-based ecology models, a generic agent-based framework not only enables the integration of existing plankton IBMs with adaptive remeshing technology, but also allows individual and population-based components to be used within a single hybrid ecosystem. This thesis gives a full account of the implementation of such a framework, focusing in particular on the movement and tracking of agents in an unstructured finite element mesh and the coupling mechanism used to facilitate agent-mesh and agent-agent interactions. The correctness of the framework is verified using an existing agent-based ecosystem model with four trophic levels, which is shown to settle on a stationary annual attractor given a stable cycle of annual forcing. A regular cycle of phytoplankton primary production and zooplankton reproduction is achieved using a purely agent-based implementation and a hybrid food chain version of the model, where the two top-level components of the ecosystem are modelled using Eulerian field equations. Finally, a standalone phytoplankton model is used to investigate the effects of vertical mesh adaptivity on the ecosystem in a three-dimensional mesh.
Quantum gauge symmetry from finite field dependent BRST transformations
Creators: name: Banerjee, Rabin
name: Mandal, Bhabani Prasad
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Using the technique of finite field dependent BRST transformations we show that the classical massive Yang-Mills theory and the pure Yang-Mills theory whose gauge symmetry is broken by a gauge fixing term are identical from the view point of quantum gauge symmetry. The explicit infinitesimal transformations which leave the massive Yang-Mills theory BRST invariant are given.
description: 8 pages, Latex, No figs
Advanced instability methods using spectral/hp discretisations and their applications to complex geometries
Creators: name: Rocco, Gabriele
Publisher: name: Imperial College London
Year: 2014

description: Controlling wakes of flows past bluff bodies is a fundamental problem in a wide range of engineering applications. In the present work, we investigate such problems theoretically and numerically using linear stability analysis. We initially consider a flow past a cylinder in a fully developed vortex shedding regime, and we apply sufficiently high spanwise forcing on the surface of the cylinder to stabilise the near-wake. The effects on the aerodynamic forces, the wake topology and the dynamics of the vorticity are investigated using spanwise sinusoidal and Gaussian forcing. Stability analysis of the linearised Navier-Stokes equations is then performed on the fully three-dimensional flow to investigate the role of the spanwise modulation on the absolute instability associated with the von-Karman street. The three-dimensional global modes allows us to detect the regions where the instability acts, and the interactions of the perturbations with the base flow shed light on the most relevant mechanism for the wake stabilisation. Additional relevant information on the design of an efficient control device are provided by receptivity analysis and the structural sensitivities. A similar approach is used to study the stability of a flow through a compressor passage at a Re=138,500. Due to the complexity of both the geometry and dynamics of the flow, a phase-averaging technique is used to generate a globally periodic basic flow, extracting only the organised structures and neglecting all the background unsteadiness. This approach allows us to perform Floquet and transient growth analyses to detect the structure of the global modes and the presence of convective instabilities.
Is a truly marginal perturbation of the $G_k\times G_k$ WZNW model at $k=-2c_V(G)$ an exception to the rule?
Creators: name: Soloviev, Oleg A.
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: It is shown that there exists a truly marginal deformation of the direct sum of two $G_k$ WZNW models at $k=-2c_V(G)$ (where $c_V(G)$ is the eigenvalue of the quadratic Casimir operator in the adjoint representation of the group $G$) which does not seem to fit the Chaudhuri-Schwartz criterion for truly marginal perturbations. In addition, a continuous family of WZNW models is constructed.
description: Latex file, 12 pp
Additional file 1: of The facilitators and barriers to implementing patient reported outcome measures in organisations delivering health related services: a systematic review of reviews
Creators: name: Foster, Alexis
name: Croot, Liz
name: Brazier, John
name: Harris, Janet
name: OâCathain, Alicia
Publisher: name: figshare
Year: 2018
Subjects: subject: Medicine
subject: Pharmacology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: 80699 Information Systems not elsewhere classified
subject: FOS: Computer and information sciences
subject: Science Policy
subject: Computational Biology

description: PRISMA checklist. (DOC 58 kb)
Supplementary document for Machine-Learning-Assisted Omnidirectional Bending Sensor Based on Cascaded Asymmetric Dual Core PCF Sensor - 6466966.pdf
Creators: name: Huang, Bingsen
name: sheng, xinzhi
name: cao, jiaqi
name: Jia, Haoqiang
name: gao, wei
name: gu, shuai
name: Wang, Xin
name: Chu, Paul
name: lou, shuqin
Publisher: name: Optica Publishing Group
Year: 2023
Subjects: Uncategorized

description: supplement
Multi-orbital nature of the spin fluctuations in Sr$_2$RuO$_4$
Creators: name: Boehnke, Lewin
name: Werner, Philipp
name: Lechermann, Frank
Publisher: name: arXiv
Year: 2018
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The spin susceptibility of strongly correlated Sr$_2$RuO$_4$ is known to display a rich structure in reciprocal space, with a prominent peak at ${\bf Q}_i$=$(0.3,0.3,0)$. It is still debated if the resulting incommensurate spin-density-wave fluctuations foster unconventional superconductivity at low temperature or compete therewith. By means of density functional theory combined with dynamical mean-field theory, we reveal the realistic multi-orbital signature of the (dynamic) spin susceptibility beyond existing weak-coupling approaches. The experimental fluctuation spectrum up to 80 meV is confirmed by theory. Furthermore, the peak at ${\bf Q}_i$ is shown to carry nearly equal contributions from each of the Ru$(4d)$-$t_\mathrm{2g}$ orbitals, pointing to a cooperative effect resulting in the dominant spin fluctuations.
description: 5 pages, 4 figures
A spectroscopic study of IRAS F10214+4724
Creators: name: Serjeant, Stephen
name: Rawlings, Steve
name: Lacy, Mark
name: McMahon, Richard G.
name: Lawrence, Andy
name: Rowan-Robinson, Michael
name: Mountain, Matt
Publisher: name: arXiv
Year: 1998
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: The z=2.286 IRAS galaxy F10214+4724 remains one of the most luminous galaxies in the Universe, despite its gravitational lens magnification. We present optical and near-infrared spectra of F10214+4724, with clear evidence for three distinct components: lines of width ~1000 km/s from a Seyfert-II nucleus;
description: Accepted for publication in MNRAS. Uses BoxedEPS (included)
On Discrete Symmetries in su(2) and su(3) Affine Theories and Related Graphs
Creators: name: Lienart, S.
name: Ruelle, P.
name: Verhoeven, O.
Publisher: name: arXiv
Year: 2000
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We classify the possible finite symmetries of conformal field theories with an affine Lie algebra su(2) and su(3), and discuss the results from the perspective of the graphs associated with the modular invariants. The highlights of the analysis are first, that the symmetries we found in either case are matched by the graph data in a perfect way in the case of su(2), but in a looser way for su(3), and second, that some of the graphs lead naturally to projective representations, both in su(2) and in su(3).
description: 34 pages, 4 eps figures
Tenthredo salicis Linnaeus, 1758, spec. nov.
Creators: name: Linnaeus, Carolus
Publisher: name: Laurentius Salvius
Year: 1758
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Tenthredinidae
Tenthredo
Tenthredo salicis

description: Tenthredo salicis [spec. nov.]
T. antennis septemnodiis, corpore flavo, vertice capitis thoracisque nigro. Fn. svec. 927.
Reaum. ins. 5. t. 11. f. 10.
Habitat in Salicibus variis.
description: Published as part of Linnaeus, Carolus, 1758, Systema Naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis, Stockholm :Laurentius Salvius on page 557, DOI: 10.5962/bhl.title.542, http://zenodo.org/record/3922206
MOESM1 of Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate
Creators: name: Satake, Noriko
name: Duong, Connie
name: Yoshida, Sakiko
name: Oestergaard, Michael
name: Chen, Cathy
name: Peralta, Rachael
name: Shuling Guo
name: Seth, Punit
name: Yueju Li
name: Beckett, Laurel
name: Chung, Jong
name: Nolta, Jan
name: Nitin Nitin
name: Tuscano, Joseph
Publisher: name: figshare
Year: 2016
Subjects: subject: Biochemistry
subject: Space Science
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Cancer
subject: Hematology

description: Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate
A methodology to automatically optimize dynamic memory managers applying grammatical evolution
Creators: name: Risco-Martín, José L.
name: Colmenar, J. Manuel
name: Hidalgo, J. Ignacio
name: Lanchares, Juan
name: Díaz, Josefa
Publisher: name: arXiv
Year: 2024
Subjects: subject: Hardware Architecture (cs.AR)
subject: FOS: Computer and information sciences

description: Modern consumer devices must execute multimedia applications that exhibit high resource utilization. In order to efficiently execute these applications, the dynamic memory subsystem needs to be optimized. This complex task can be tackled in two complementary ways: optimizing the application source code or designing custom dynamic memory management mechanisms. Currently, the first approach has been well established, and several automatic methodologies have been proposed. Regarding the second approach, software engineers often write custom dynamic memory managers from scratch, which is a difficult and error-prone work. This paper presents a novel way to automatically generate custom dynamic memory managers optimizing both performance and memory usage of the target application. The design space is pruned using grammatical evolution converging to the best dynamic memory manager implementation for the target application. Our methodology achieves important improvements (62.55\% and 30.62\% better on average in performance and memory usage, respectively) when its results are compared to five different general-purpose dynamic memory managers.
Consistent deformations of free massive field theories in the Stueckelberg formulation
Creators: name: Boulanger, Nicolas
name: Deffayet, Cédric
name: Garcia-Saenz, Sebastian
name: Traina, Lucas
Publisher: name: arXiv
Year: 2018
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Cohomological techniques within the Batalin-Vilkovisky (BV) extension of the Becchi-Rouet-Stora-Tyutin (BRST) formalism have proved invaluable for classifying consistent deformations of gauge theories. In this work we investigate the application of this idea to massive field theories in the Stueckelberg formulation. Starting with a collection of free massive vectors, we show that the cohomological method reproduces the cubic and quartic vertices of massive Yang-Mills theory. In the same way, taking a Fierz-Pauli graviton on a maximally symmetric space as the starting point, we are able to recover the consistent cubic vertices of nonlinear massive gravity. The formalism further sheds light on the characterization of Stueckelberg gauge theories, by demonstrating for instance that the gauge algebra of such models is necessarily Abelian and that they admit a Born-Infeld-like formulation in which the action is simply a combination of the gauge-invariant structures of the free theory.
description: 30+7 pages; v2: references added
Conformal Anomaly of String Theory in the Harmonic Gauge
Creators: name: Takahashi, Tomohiko
Publisher: name: arXiv
Year: 1995
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Considering the conformal anomaly in an effective action, the critical dimension of string theory can be decided in the harmonic gauge, in which it had been reported before to be indefinite. In this gauge, there is no anomaly for the ghost number symmetry. This can be naturally understood in terms of Faddeev-Popov conjugation in the theory.
description: 13 pages + 4 uuencoded eps figures, LaTeX
Plasticity as the $Γ$-Limit of a Two-Dimensional Dislocation Energy: the Critical Regime without the Assumption of Well-Separateness
Creators: name: Ginster, Janusz
Publisher: name: arXiv
Year: 2018
Subjects: subject: Analysis of PDEs (math.AP)
subject: Optimization and Control (math.OC)
subject: FOS: Mathematics
subject: 49J45, 58K45, 74C05

description: In this paper, a strain-gradient plasticity model is derived from a mesoscopic model for straight parallel edge dislocations in an infinite cylindrical crystal. The main difference to existing work is that in this work the well-separateness of disloactions is not assumed. In order to prove meaningful lower bounds the ball construction technique, which was developed in the context of Ginzburg-Landau by Jerrard and Sandier, is adapted and modified. To overcome the difficulty of a loss of rigidity on thin annuli during the ball construction a combination of combinatorial arguments and local modifications of the occurring elastic strains is presented.
description: 37 pages, 5 figures
Electrovariable liquid interfaces for optical applications: structure and dynamics
Creators: name: Marinescu, Monica
Publisher: name: Imperial College London
Year: 2012

description: Due to their versatility, liquid/liquid interfaces are currently of great interest for a variety of optical applications, such as variable-focus lenses, microfluidics, optical switches and display elements. This thesis explores the properties of the electrified interface between two immiscible electrolytic solutions (ITIES ) in two types of systems. The ITIES formed between a droplet and the surrounding liquid, supported on an electrode, has been shown to provide a viable ultra-low-voltage alternative to currently used systems. Due to the electrowetting effect, significant changes in the contact angle are obtained as the result of small variations in the applied voltage, 1 V. On real electrodes, chemical and physical inhomogeneities were found to lead to significant hysteresis of the contact angle variation. Pulsed voltage was used to reduce hysteresis and increase the interval of angles reached. A theoretical model of the droplet dynamics is developed by analogy to the harmonic oscillator. The predicted time-dependent motion of the system rationalises the behaviour observed experimentally, and helps in the design of viable systems. The developed model could also provide a new framework for the study of the role of friction in wetting dynamics. Beside changing its shape, another way to functionalise the ITIES is by allowing nanoparticles to spontaneously assemble at the interface. Once localised, their arrangement greatly influences the response of the system to incident light. An external voltage can control the response time and the structure of this assembly, as well as make it reversible. Such systems are of great interest for controllable optics and sensing applications. There are few independent characterisation methods of populated interfaces. A model is developed for the capacitance of an ITIES populated by metal nanoparticles. Model predictions allow to extract important information from capacitance measurements on the structure of the adsorbed layer, promoting this method as a quantitative characterisation tool. The Faraday rotation from a monolayer of dielectric nanoparticles at an ITIES is calculated in a dipolar approximation. The particle density is assumed to be reversibly controlled by an applied potential. The difference between the angle of rotation caused by particles dissolved in the bulk and that caused by a monolayer arrangement is predicted to be large enough to make low-energy switchable Faraday isolators possible.
Audit Firm Attributes and Fees in Nigeria Listed Pharmaceutical Firms
Creators: name: Ekundayo, Oyindamola
Publisher: name: figshare
Year: 2022
Subjects: subject: 150199 Accounting, Auditing and Accountability not elsewhere classified
subject: FOS: Economics and business
subject: 150103 Financial Accounting
subject: 150106 Sustainability Accounting and Reporting

description: The determination of audit fees is, as well, a matter and of concern to the auditor who is required by law to be independent in the conduct of his audit work as well as charge a fee that will not be too high, threatening his independence, or too low to cover the risk and cost of the audit assignment. Thus, this study seeks to ascertain those audit firm characteristics that determine the audit fees of listed pharmaceutical firms in Nigeria for the six-year period from 2012 to 2017. The panel research design is adopted for the study and secondary data are obtained from the published annual reports and accounts of the sample of7 out of the population of 11 firms via purposive sampling technique, and ana]ysed using descriptive statistics, correlation and multiple regression techniques.
title: ADCO, Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402) (11 H 1160), f. 00059
Creators: name: de la Côte-d'Or, Archives départementales
name: Archives Départementales De La Côte-D'Or
name: Petot, Frédérique
name: Projet CBMA
name: CBMA/CG21/F.PETOT/2017
name: Petot, Frédéric
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2020
Subjects: subject: Corpus Burgundiae Medii Aevi
subject: Chartes de la Bourgogne du Moyen Âge
subject: comptes
subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160). Numérisation en mode image.
description: Relation: http://www.cbma-project.eu/
description: Bibliographic citation: Ordre cistercien et abbaye de Cîteaux : comptes pour l'ordre (1337-1347), comptes du boursier (1377-1402), Archives départementales de la Côte-d'Or, (11 H 1160), f. 00059, in Projet CBMA - Corpus Burgundiae Medii Aevi \[Ressource en ligne\], https:// manuscrits.cbma-project.eu/
description: Provenance: https://www.geonames.org/3024876
description: Provenance: http://www.idref.fr/030974844/id
description: Provenance: https://catalogue.bnf.fr/ark:/12148/cb12228351v
description: Provenance: abbaye de Cîteaux
description: Provenance: http://www.wikidata.org/entity/Q843261
Lead-Related Quantum Emitters in Diamond
Creators: name: Trusheim, Matthew E.
name: Wan, Noel H.
name: Chen, Kevin C.
name: Ciccarino, Christopher J.
name: Sundararaman, Ravishankar
name: Malladi, Girish
name: Bersin, Eric
name: Walsh, Michael
name: Lienhard, Benjamin
name: Bakhru, Hassaram
name: Narang, Prineha
name: Englund, Dirk
Publisher: name: arXiv
Year: 2018
Subjects: subject: Quantum Physics (quant-ph)
subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: We report on quantum emission from Pb-related color centers in diamond following ion implantation and high temperature vacuum annealing. First-principles calculations predict a negatively-charged Pb-vacancy center in a split-vacancy configuration, with a zero-phonon transition around 2.3 eV. Cryogenic photoluminescence measurements performed on emitters in nanofabricated pillars reveal several transitions, including a prominent doublet near 520 nm. The splitting of this doublet, 2 THz, exceeds that reported for other group-IV centers. These observations are consistent with the PbV center, which is expected to have the combination of narrow optical transitions and stable spin states, making it a promising system for quantum network nodes.
Synergy between habitat fragmentation and climate change: implications for biodiversity in Alpine ecosystems
Creators: name: Pilia, Oriana
Publisher: name: Imperial College London
Year: 2011

description: An increase in global temperature accompanied by rapid fragmentation of habitats will lead to greater pressure on biodiversity, with more dramatic impacts expected on high mountain ranges. A new wave of extinction is likely to occur as the ability of species to migrate toward new cooler suitable areas will be hampered by altered landscapes, also the magnitude of species loss will in part depend on species traits, or phenotypic plasticity of individuals which will have to adapt to the changed environmental conditions. In this PhD thesis, I included different models employing altitudinal gradient as a surrogate, to understand how effects determined by climatic variation might or might not exacerbate the negative impact of landscape changes on carabid communities (eastern Italian Alps). Chapter I contains a brief overview of the current body of scientific literature on the main ecological impacts of habitat fragmentation and climate change, and the emerging research related to the response of organisms to the synergistic impacts of these two threats. The aim of Chapter II is to determine whether the effects of rising temperature might enhance the impact of habitat fragmentation on beetle diversity and community structure. Chapter III describes an attempt to assess the existence of simultaneous effects generated by habitat fragmentation and climate change on variation of morphological traits (fluctuating asymmetry and body length) in natural populations of forest-dwelling species Haptoderus unctulatus. Finally, Chapter IV explores if species’ sensitivity to landscape modification and altitude might be maximized or not by a combination of life history traits of ground beetles. In summary, data of carabid assemblages suggest that the impact of rising temperature acting in synergy with land use pressure will move up along the mountainside, inflicting more serious negative impact on species composition, and causing changes in morphological traits of beetle populations particularly accentuated at lowlands. Also, interaction between these two drivers of change will exert a selective pressure on species with certain functional traits, which will result in a greater impact on the beetle assemblages of Alpine ecosystems than either driver acting individually.