cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Turbidity currents propagating down an inclined slope: particle auto-suspension
Creators: name: Xie, Jiafeng
name: Hu, Peng
name: Zhu, Chenlin
name: Yu, Zhaosheng
name: Pähtz, Thomas
Publisher: name: arXiv
Year: 2023
Subjects: subject: Fluid Dynamics (physics.flu-dyn)
subject: Geophysics (physics.geo-ph)
subject: FOS: Physical sciences

description: The Turbidity current (TC), a ubiquitous fluid-particle coupled phenomenon in the natural environment and engineering, can transport over long distances on an inclined terrain due to the suspension mechanism. A large-eddy simulation and discrete element method coupled model is employed to simulate the particle-laden gravity currents over the inclined slope in order to investigate the auto-suspension mechanism from a Lagrangian perspective. The particle Reynolds number in our TC simulation is $0.01\sim0.1$ and the slope angle is $1/20 \sim 1/5$. The influences of initial particle concentration and terrain slope on the particle flow regimes, particle movement patterns, fluid-particle interactions, energy budget and auto-suspension index are explored. The results indicate that the auto-suspension particles predominantly appear near the current head and their number increases and then decreases during the current evolution, which is positively correlated with the coherent structures around the head. When the turbidity current propagates downstream, the average particle Reynolds number of the auto-suspension particles remains basically unchanged, and is higher than that of other transported particles. The average particle Reynolds number of the transported particles exhibits a negative correlation with the Reynolds number of the current. Furthermore, the increase in particle concentration will enhance the particle velocity, which allows the turbidity current to advance faster and improves the perpendicular support, thereby increasing the turbidity current auto-suspension capacity. Increasing slope angle will result in a slightly larger front velocity, while the effect of that on the total force is insignificant.
(103132) Frederick Snellgrove Ellison
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Nitric Oxide-Releasing Dendrimers as Antibacterial Agents
Creators: name: Slomberg, Danielle L.
name: Chudasama, Shalini L.
name: Lu, Yuan
name: Sun, Bin
name: Schoenfisch, Mark H.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: The antibacterial activity of a series of nitric oxide (NO)-releasing poly(propylene imine) (PPI) dendrimers was evaluated against both Gram-positive and Gram-negative pathogenic bacteria, including methicillin-resistant Staphylococcus aureus. A direct comparison of the bactericidal efficacy between NO-releasing and control PPI dendrimers (i.e., non-NO-releasing) revealed both enhanced biocidal action of NO-releasing dendrimers and reduced toxicity against mammalian fibroblast cells. Antibacterial activity for the NO donor-functionalized PPI dendrimers was shown to be a function of both dendrimer size (molecular weight) and exterior functionality. In addition to minimal toxicity against fibroblasts, NO-releasing PPI dendrimers modified with styrene oxide exhibited the greatest biocidal activity (≥9.999% killing) against all bacterial strains tested. The N-diazeniumdiolate NO donor-functionalized PPI dendrimers presented in this study hold promise as effective NO-based therapeutics for combating bacterial infections.
Stefanie Martin-Kilcher, Die römischen Amphoren aus Augst und Kaiseraugst
Creators: name: Simon, Hans-Günther
Publisher: name: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts
Year: 2023

description: Rezension zu: Stefanie Martin-Kilcher, Die römischen Amphoren aus Augst und Kaiseraugst. Ein Beitrag zur römischen Handels- und Kulturgeschichte. 1: Die südspanischen Ölamphoren (Gruppe 1). Forschungen in Augst Band 7. Römermuseum Augst, Augst 1987. ISBN 3-7151-0007-2. 311 Seiten, 94 Tafeln, 119 Abbildungen und 3 Beilagen.
description: Germania : Anzeiger der Römisch-Germanischen Kommission des Deutschen Archäologischen Instituts, Bd. 68 Nr. 1 (1990)
Trinification from $\mathrm{E}_{6}$ symmetry breaking
Creators: name: Babu, K. S.
name: Bajc, Borut
name: Susič, Vasja
Publisher: name: arXiv
Year: 2023
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: In the context of $\mathrm{E}_{6}$ Grand Unified Theories (GUTs), an intriguing possibility for symmetry breaking to the Standard Model (SM) group involves an intermediate stage characterized by either $\mathrm{SU}(3)\times\mathrm{SU}(3)\times\mathrm{SU}(3)$ (trinification) or $\mathrm{SU}(6)\times\mathrm{SU}(2)$. The more common choices of $\mathrm{SU(5)}$ and $\mathrm{SO}(10)$ GUT symmetry groups do not offer such breaking chains. We argue that the presence of a real (rank $2$ tensor) representation $\mathbf{650}$ of $\mathrm{E}_{6}$ in the scalar sector is the minimal and likely only reasonable possibility to obtain one of the novel intermediate stages. We analyze the renormalizable scalar potential of a single copy of the $\mathbf{650}$ and find vacuum solutions that support regularly embedded subgroups $\mathrm{SU}(3)\times\mathrm{SU}(3)\times\mathrm{SU}(3)$, $\mathrm{SU}(6)\times\mathrm{SU}(2)$, and $\mathrm{SO}(10)\times\mathrm{U}(1)$, as well as specially embedded subgroups $\mathrm{F}_{4}$ and $\mathrm{SU}(3)\times\mathrm{G}_{2}$ that do not contain the SM gauge symmetry. We show that for a suitable choice of parameters, each of the regular cases can be obtained as the lowest among the analyzed minima in the potential.
description: 29 pages, 15 tables, 3 figures
(103131) Frederick Edwin Ellison
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
MPEC 2023-T211 : 2009 WW25
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
2mm Observations and the Search for High-Redshift Dusty Star-forming Galaxies
Creators: name: Cowie, L. L.
name: Barger, A. J.
name: Bauer, F. E.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: Finding high-redshift (z>>4) dusty star-forming galaxies is extremely challenging. It has recently been suggested that millimeter selections may be the best approach, since the negative K-correction makes galaxies at a given far-infrared (FIR) luminosity brighter at z>4 than those at z=2-3. Here we analyze this issue using a deep ALMA 2mm sample obtained by targeting ALMA 870um priors (these priors were the result of targeting SCUBA-2 850um sources) in the GOODS-S. We construct the prior-based 2mm galaxy number counts and compare them with published blank field-based 2mm counts, finding good agreement down to 0.2mJy. Only a fraction of the current 2mm extragalactic background light is resolved, and we estimate what observational depths may be needed to resolve it fully. By complementing the 2mm ALMA data with a deep SCUBA-2 450um sample in the GOODS-S, we exploit the steep gradient with redshift of the 2mm to 450um flux density ratio to estimate redshifts for these galaxies without spectroscopic or robust optical/near-infrared photometric redshifts. Our observations measure galaxies with star formation rates in excess of 250 solar masses per year. For these galaxies, the star formation rate densities fall by a factor of 9 from z=2-3 to z=5-6.
description: 14 pages, 8 figures. ApJ, in press
Accelerating Unruh-DeWitt detectors coupled with a spinor field
Creators: name: Wu, Dawei
name: Tang, Shan-Chang
name: Shi, Yu
Publisher: name: arXiv
Year: 2023
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: FOS: Physical sciences

description: The behavior of accelerating Unruh-DeWitt detectors coupled with a spinor field in (3+1)-dimensional spacetime is investigated. For a single point-like detector with Gaussian switching function, the transition probability increases with the acceleration and thus the antiUnruh effect effect cannot occur. Due to the spinor structure of the Dirac field, UV divergences are encountered in the calculation of the entanglement between the detectors. After introducing some UV cutoff $Λ$, the logarithmic negativity of detectors is shown to behave nonmonotonically with respect to the acceleration. Besides, the logarithmic negativity increases with the cutoff $Λ$ and decreases with the distance between the detectors. The mutual information between the two detectors is also discussed.
description: 30 pages
Infrared multiphoton resummation in quantum electrodynamics
Creators: name: Mati, P.
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Infrared singularities in massless gauge theories are known since the foundation of quantum field theories. The root of this problem can be tracked back to the very definition of these long-range interacting theories such as QED. It can be shown that singularities are caused by the massless degrees of freedom (i.e. the photons in the case of QED). In the Bloch-Nordsieck model the absence of the infrared catastrophe can be shown exactly by the complete summation of the radiative corrections. In this paper we will give the idea of the derivation of the Bloch-Nordsieck propagator, that describes the infrared structure of the electron propagation, at zero and finite temperatures. Some ideas of the possible applications are also mentioned.
description: 8 pages, 6 figures, uses revtex4-1, submitted to the proceedings of the PIPAMON 2015 International Workshop
Unexpected Multivalent Display of Proteins by Temperature Triggered Self-Assembly of Elastin-like Polypeptide Block Copolymers
Creators: name: Branscheid, Robert
name: Liu, Rihe
name: Chilkoti, Ashutosh
name: Fu, Chuan Lawrence
name: MacEwan, Sarah R.
name: Schmidt, Manfred
name: Fischer, Karl
name: Hassouneh, Wafa
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: We report herein the unexpected temperature triggered self-assembly of proteins fused to thermally responsive elastin-like polypeptides (ELPs) into spherical micelles. Six ELP block copolymers (ELPBC) with different hydrophilic and hydrophobic block lengths were genetically fused to two single domain proteins, thioredoxin (Trx) and a fibronectin type III domain (Fn3) that binds the αvβ3 integrin. The self-assembly of these protein-ELPBC fusions as a function of temperature was investigated by UV spectroscopy, light scattering, and cryo-TEM. Self-assembly of the ELPBC was –unexpectedly- retained upon fusion to the two proteins, resulting in the formation of spherical micelles with a hydrodynamic radius that ranged from 24–37 nm, depending on the protein and ELPBC. Cryo-TEM images confirmed the formation of spherical particles with a size that was consistent with that measured by light scattering. The bioactivity of Fn3 was retained when presented by the ELPBC micelles as indicated by the enhanced uptake of the Fn3-decorated ELPBC micelles in comparison to the unimer by cells that overexpress the αvβ3 integrin. The fusion of single domain proteins to ELPBCs may provide a ubiquitous platform for the multivalent presentation of proteins.
Superfluidity of a dipolar Fermi gas in 2D optical lattices bilayer
Creators: name: Camacho-Guardian, A.
name: Paredes, R.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We propose a model for addressing the superfluidity of two different Fermi species confined in a bilayer geometry of square optical lattices. The fermions are assumed to be molecules with interlayer s-wave interactions, whose dipole moments are oriented perpendicularly to the layers. Using functional integral techniques we investigate the BCS-like state induced in the bilayer at finite temperatures. In particular, we determine the critical temperature as a function of the coupling strength between molecules in different layers and of the interlayer spacing. By means of Ginzburg-Landau theory we calculate the superfluid density. We also study the dimerized BEC phase through the Berezinskii-Kosterlitz-Thouless transition, where the effective mass leads to identify the crossover from BCS to BEC regimes. The possibility of tuning the effective mass as a direct consequence of the lattice confinement, allows us to suggest a range of values of the interlayer spacing, which would enable observing this superfluidity within current experimental conditions.
description: 11 pages, 5 figures
Key Structure of Brij for Overcoming Multidrug Resistance in Cancer
Creators: name: Wang, Yongjun
name: Tang, Jingling
name: Wang, Yuhua
name: Xu, Zhenghong
name: Liu, Feng
name: Racette, Kelly
name: Wang, Dun
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Multidrug resistance (MDR) is a major barrier to the chemotherapy treatment of many cancers. However, some non-ionic surfactants, for example Brij, have been shown to restore the sensitivity of MDR cells to such drugs. The aim of this study was to explore the reversal effect of Brij on MDR tumor cells and elucidate its potential mechanism. Our data indicate that the structure of Brij surfactants plays an important role in overcoming MDR in cancer, i.e. modified hydrophilic-lipophilic balance (MHLB, the ratio of the number (n) of hydrophilic repeating units of ethylene oxide (EO) to the number (m) of carbons in the hydrophobic tail (CH2).). Cell viability of cells treated with paclitaxel (PTX) nanocrystals (NCs) formulated with Brij showed positive correlations with MHLB (R2 = 0.8195); the higher the ratio of Brij to PTX in NCs, the higher cytotoxicity induced by the PTX NCs. Significant increases in intracellular accumulation of 3H-PTX (P-gp substrate) were observed in an MDR cell line (H460/taxR cells) treated with Brij 78 (MHLB=1.11) and Brij 97 (MHLB=0.6). After treatments with Brij 78 and Brij 97, the levels of intracellular ATP were decreased and verapamil induced ATPase activities of P-gp were inhibited in multidrug resistant cells. The responses of the cells to Brij 78 and Brij 97 in ATP depletion studies correlated with the cell viability induced by PTX/Brij NCs and intracellular accumulation of 3H-PTX. Brij 78 and Brij 97 could not alter the levels of P-gp expression detected by western blotting. These findings may provide some insight into the likelihood of further development of more potent P-gp inhibitors for the treatment of MDR in cancer.
Large-scale turbulent driving regulates star formation in high-redshift gas-rich galaxies II: Influence of the magnetic field and the turbulent compressive fraction
Creators: name: Brucy, Noé
name: Hennebelle, Patrick
name: Colman, Tine
name: Iteanu, Simon
Publisher: name: arXiv
Year: 2023
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: FOS: Physical sciences

description: The observed star formation rate (SFR) in galaxies is well below what it should be if gravitational collapse alone were at play. It has recently been shown that one candidate that might regulate star formation, the feedback from massive stars, is suitable only if the mean column density at the kiloparsec scale is lower than $\approx 20 M_\odot\cdot\mathrm{pc}^{-2}$. On the other hand, intense large-scale turbulent driving might slow down star formation in high-density environments to values that are compatible with observations. In this work, we explore the effect of the nature and strength of the turbulent driving, as well as the effect of the magnetic field. We performed a large series of feedback-regulated numerical simulations of the interstellar medium in which bidimensional large-scale turbulent driving was also applied. We determined the driving intensity needed to reproduce the Schmidt-Kennicutt relation for several gas column densities, magnetization, and driving compressibility. We confirm that in the absence of turbulent forcing and even with a substantial magnetic field, the SFR is too high, particularly at a high column density, compared to the Schmidt-Kennicutt relation. We find that the SFR outcome strongly depends on the initial magnetic field and on the compressibility of the turbulent driving. As a consequence, a higher magnetic field in high column density environment may lower the energy necessary to sustain a turbulence that is sufficiently intense to regulate star formation. Stellar feedback does not seem to be sufficient to regulate star formation in gas-rich galaxies where large-scale turbulent driving may be needed. The sources of this large-scale turbulence as well as its characteristics, such as its intensity, compressibility, and anisotropy, need to be understood and quantified.
description: 16 pages, 14 figures, accepted for publication in A&A
Nitric Oxide-Releasing Amphiphilic Poly(amidoamine) (PAMAM) Dendrimers as Antibacterial Agents
Creators: name: Slomberg, Danielle L.
name: Schoenfisch, Mark H.
name: Lu, Yuan
name: Shah, Anand
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: A series of amphiphilic nitric oxide (NO)-releasing poly(amidoamine) (PAMAM) dendrimers with different exterior functionalities were synthesized by a ring-opening reaction between primary amines on the dendrimer and propylene oxide (PO), 1,2-epoxy-9-decene (ED), or a ratio of the two, followed by reaction with NO at 10 atm to produce N-diazeniumdiolate-modified scaffolds with a total storage of ~1 μmol/mg. The hydrophobicity of the exterior functionality was tuned by varying the ratio of PO and ED grafted onto the dendrimers. The bactericidal efficacy of these NO-releasing vehicles against established Gram-negative Pseudomonas aeruginosa biofilms was then evaluated as a function of dendrimer exterior hydrophobicity (i.e., ratio of PO/ED), size (i.e., generation), and NO release. Both the size and exterior functionalization of dendrimer proved important to a number of parameters including dendrimer-bacteria association, NO delivery efficiency, bacteria membrane disruption, migration within the biofilm, and toxicity to mammalian cells. Although enhanced bactericidal efficacy was observed for the hydrophobic chains (e.g., ED), toxicity to L929 mouse fibroblast cells was also noted at concentrations necessary to reduce bacterial viability by 5-logs (99.999% killing). The optimal PO to ED ratios for biofilm eradication with minimal toxicity against L929 mouse fibroblast cells were 7:3 and 5:5. The study presented herein demonstrated the importance of both dendrimer size and exterior properties in determining efficacy against established biofilms without compromising biocompatibility to mammalian cells.
(103130) Edward Venture Mardon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103129) Sarah Anne Mardon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103128) Dolly Mardon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Fate of the "vacuum point'' and of grey solitons in dispersive quantum shock waves in a one-dimensional Bose gas
Creators: name: Simmons, S. A.
name: Pillay, J. C.
name: Kheruntsyan, K. V.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Pattern Formation and Solitons (nlin.PS)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: We continue the study of dispersive quantum shock waves in a one-dimensional Bose gas beyond the mean-field approximation. In a recent work by Simmons et al. [Phys. Rev. Let. 125, 180401 (2020)], the oscillatory shock wave train developing in this system from an initial localized density bump on a uniform background was interpreted as a result of quantum mechanical self-interference, wherein the interference contrast would diminish with the loss of matter-wave phase coherence. Such loss of coherence, relative to the mean-field Gross-Pitaevskii description, occurs due to either quantum or thermal fluctuations, as well as in the strongly interacting regime. In this work, we extend the analysis of dispersive quantum shock waves in this context to other dynamical scenarios. More specifically, the scenarios studied include evolution of a sufficiently high density bump, known to lead to the so-called ``vacuum point'' in the mean-field description, and evolution of an initial density dip, known to shed a train of grey solitons in the same mean-field approximation. We study the fate of these nonlinear wave structures in the presence of quantum and thermal fluctuations, as well as at intermediate and strong interactions, and show that both the vacuum point and grey solitons cease to manifest themselves beyond the mean-field approach. On the other hand, we find that a vacuum point can occur in an ideal (noninteracting) Bose gas evolving from a ground state of a localized dimple potential. Due to the ubiquity of dispersive shock waves in nature, our results should provide useful insights and perspectives for a variety of other physical systems known to display nonlinear wave phenomena.
description: 20 pages, 10 figures
(103127) George Mardon
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
Regularization by Discretization in Banach Spaces
Creators: name: Hämarik, Uno
name: Kaltenbacher, Barbara
name: Kangro, Urve
name: Resmerita, Elena
Publisher: name: arXiv
Year: 2015
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: 65J20, 65J22, 65R32

description: We consider ill-posed linear operator equations with operators acting between Banach spaces. For solution approximation, the methods of choice here are projection methods onto finite dimensional subspaces, thus extending existing results from Hilbert space settings. More precisely, general projection methods, the least squares method and the least error method are analyzed. In order to appropriately choose the dimension of the subspace, we consider a priori and a posteriori choices by the discrepancy principle and by the monotone error rule. Analytical considerations and numerical tests are provided for a collocation method applied to a Volterra integral equation in one space dimension.
Bio-Inspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin
Creators: name: Gu, Zhen
name: Mo, Ran
name: Buse, John B.
name: Gu, Xiao
name: Subramanian, Vinayak
name: Tai, Wanyi
name: Di, Jin
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2014

description: A new glucose-responsive formulation for self-regulated insulin delivery was constructed by packing insulin, glucose-specific enzymes into pH-sensitive polymersome-based nanovesicles assembled by a diblock copolymer. Glucose can passively transport across the bilayer membrane of the nanovesicle and be oxidized into gluconic acid by glucose oxidase, thereby causing a decrease in local pH. The acidic microenvironment causes the hydrolysis of the pH sensitive nanovesicle that in turn triggers the release of insulin in a glucose responsive fashion. In vitro studies validated that the release of insulin from nanovesicle was effectively correlated with the external glucose concentration. In vivo experiments, in which diabetic mice were subcutaneously administered with the nanovesicles, demonstrate that a single injection of the developed nanovesicle facilitated stabilization of the blood glucose levels in the normoglycemic state (<200 mg/dL) for up to 5 days.
Comparison of three oxidative stress biomarkers in a sample of healthy adults Oxidative stress biomarkers in healthy adults J. L. Watters et al.
Creators: name: Costa, Kerry Ann Da
name: Watters, Joanne L.
name: Milne, Ginger L.
name: Morrow, Jason D.
name: Boysen, Gunnar
name: Collins, Leonard B.
name: Swenberg, James A.
name: Satia, Jessie A.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Oxidative stress is a potentially important etiologic factor for many chronic diseases, including cardiovascular disease, neurodegenerative disease, and cancer, yet studies often find inconsistent results. The associations between three of the most widely-used biomarkers of oxidative stress, i.e., F2-isoprostanes for lipid peroxidation and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) and the comet assay with FPG for oxidative DNA damage, were compared in a sample of 135 healthy African American and White adults. Modest associations were observed between F2-isoprostanes and the comet assay (r=0.22, p=0.01), but there were no significant correlations between 8-oxo-dG and the comet assay (r=−0.09) or F2-IsoP (r=−0.04). These results are informative for researchers seeking to compare results pertaining to oxidative stress across studies and/or assessment methods in healthy disease-free populations. The development and use of oxidative stress biomarkers is a promising field; however, additional validation studies are necessary to establish accuracy and comparability across oxidative stress biomarkers.
Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients
Creators: name: O'Connell, Thomas M.
name: Esther Jr., Charles R.
name: Wolak, Justyna E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2009

description: Metabolite profiles of bronchoalveolar lavage fluid (BALF) from pediatric patients with cystic fibrosis (CF) were correlated to the degree of airway inflammation using nuclear magnetic resonance spectroscopy-based metabolomics. BALF was collected from 11 children with CF during clinically indicated bronchoscopy. The spectra from BALF with high levels of neutrophilic airway inflammation displayed signals from numerous metabolites, whereas the spectra from subjects with low levels of inflammation were very sparse. The metabolites identified in samples taken from subjects with high inflammation include known markers of inflammation such as amino acids and lactate, as well as many novel signals. Statistical analysis highlighted the most important metabolites that distinguished the high- from the low-inflammation groups. This first demonstration of metabolomics of human BALF shows that clear distinctions in the metabolic profiles can be observed between subjects experiencing high versus low inflammation and is a first step toward the goal of discovering novel biomarkers of airway inflammation.
Convex Integration and Legendrian Approximation of Curves
Creators: name: Hungerbühler, Norbert
name: Mettler, Thomas
name: Wasem, Micha
Publisher: name: arXiv
Year: 2015
Subjects: subject: Differential Geometry (math.DG)
subject: Classical Analysis and ODEs (math.CA)
subject: FOS: Mathematics

description: Using convex integration we give a constructive proof of the well-known fact that every continuous curve in a contact $3$-manifold can be approximated by a Legendrian curve.
description: Final Version, to appear in Journal of Convex Analysis, 9 pages, 1 figure
Exposure to naphthalene induces naphthyl-keratin adducts in human epidermis in vitro and in vivo
Creators: name: Nylander-French, Leena A.
name: Stober, Vandy P.
name: Kang-Sickel, Juei Chuan C.
name: French, John E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: We observed naphthyl-keratin adducts and dose-related metabolic enzyme induction at the mRNA level in reconstructed human epidermis in vitro after exposure to naphthalene. Immunofluorescence detection of 2-naphthyl-keratin-1 adducts confirmed the metabolism of naphthalene and adduction of keratin. We also observed naphthyl-keratin adducts in dermal tape-strip samples collected from naphthalene-exposed workers at levels ranging from 0.004 to 6.104 pmole adduct/μg keratin. We have demonstrated the ability of the human skin to metabolize naphthalene and to form naphthyl-keratin adducts both in vitro and in vivo. The results indicate the potential use of keratin adducts as biomarkers of dermal exposure.
Leveraging a Probabilistic PCA Model to Understand the Multivariate Statistical Network Monitoring Framework for Network Security Anomaly Detection
Creators: name: Pérez-Bueno, Fernando
name: García, Luz
name: Maciá-Fernández, Gabriel
name: Molina, Rafael
Publisher: name: arXiv
Year: 2023
Subjects: subject: Machine Learning (stat.ML)
subject: Machine Learning (cs.LG)
subject: FOS: Computer and information sciences

description: Network anomaly detection is a very relevant research area nowadays, especially due to its multiple applications in the field of network security. The boost of new models based on variational autoencoders and generative adversarial networks has motivated a reevaluation of traditional techniques for anomaly detection. It is, however, essential to be able to understand these new models from the perspective of the experience attained from years of evaluating network security data for anomaly detection. In this paper, we revisit anomaly detection techniques based on PCA from a probabilistic generative model point of view, and contribute a mathematical model that relates them. Specifically, we start with the probabilistic PCA model and explain its connection to the Multivariate Statistical Network Monitoring (MSNM) framework. MSNM was recently successfully proposed as a means of incorporating industrial process anomaly detection experience into the field of networking. We have evaluated the mathematical model using two different datasets. The first, a synthetic dataset created to better understand the analysis proposed, and the second, UGR'16, is a specifically designed real-traffic dataset for network security anomaly detection. We have drawn conclusions that we consider to be useful when applying generative models to network security detection.
Influence of the inverse magnetic catalysis and the vector interaction in the location of the critical end point
Creators: name: Costa, Pedro
name: Ferreira, Márcio
name: Menezes, Débora P.
name: Moreira, João
name: Providência, Constança
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The effect of a strong magnetic field on the location of the critical end point (CEP) in the QCD phase diagram is discussed under different scenarios. In particular, we consider the contribution of the vector interaction and take into account the inverse magnetic catalysis obtained in lattice QCD calculations at zero chemical potential. The discussion is realized within the (2+1) Polyakov--Nambu--Jona-Lasinio model. It is shown that the vector interaction and the magnetic field have opposite competing effects, and that the winning effect depends strongly on the intensity of the magnetic field. The inverse magnetic catalysis at zero chemical potential has two distinct effects for magnetic fields above $\gtrsim 0.3$ GeV$^2$: it shifts the CEP to lower chemical potentials, hinders the increase of the CEP temperature and prevents a too large increase of the baryonic density at the CEP. For fields $eB<0.1$ GeV$^2$ the competing effects between the vector contribution and the magnetic field can move the CEP to regions of temperature and density in the phase diagram that could be more easily accessible to experiments.
description: 12 pages, 9 figures; PRD version
Hemoglobin adducts in workers exposed to 1,6-hexamethylene diisocyanate
Creators: name: Flack, Sheila L.
name: Gaines, Linda G.T.
name: Thomasen, Jennifer M.
name: Nylander-French, Leena A.
name: Fent, Kenneth W.
name: Ball, Louise M.
name: Whittaker, Stephen G.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: We investigated the utility of 1,6-hexamethylene diamine (HDA) hemoglobin adducts as biomarkers of exposure to 1,6-hexamethylene diisocyanate (HDI) monomer. Blood samples from 15 spray painters applying HDI-containing paint were analyzed for hemoglobin HDA (HDA-Hb) and N-acetyl-1,6-hexamethylene diamine (monoacetyl-HDA-Hb) by GC-MS. HDA-Hb was detected in the majority of workers (≤1.2–37 ng/g Hb), whereas monoacetyl-HDA-Hb was detected in one worker (0.06 ng/g Hb). The stronger, positive association between HDA-Hb and cumulative HDI exposure (r2 = 0.3, p < 0.06) than same day exposure (p ≥ 0.13) indicates long-term elimination kinetics for HDA-Hb adducts. This association demonstrates the suitability of HDA-Hb adducts for further validation as a biomarker of HDI exposure.
Adhesion molecules, endothelin-1 and lung function in seven population-based cohorts
Creators: name: Allison, M.
name: Barr, R. G.
name: Rabinowitz, D.
name: Kumar, R.
name: Lange, L. A.
name: Rich, S. S.
name: Burkart, K. M.
name: Redline, S.
name: Petrini, M. F.
name: Tracy, R. P.
name: London, S. J.
name: Oelsner, E. C.
name: Raghavan, S.
name: Wilk, J. B.
name: Thyagarajan, B.
name: O'Connor, G. T.
name: Hansel, N. N.
name: Papanicolaou, G.
name: White, W. B.
name: Buxbaum, S. G.
name: Pottinger, T. D.
name: Loehr, L. R.
name: Larkin, E. K.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: Endothelial function is abnormal in chronic obstructive pulmonary disease (COPD); whether endothelial dysfunction causes COPD is unknown.
A cube Slice that is not a Zonoid
Creators: name: Anantharaman, R .
Publisher: name: arXiv
Year: 2023
Subjects: subject: Combinatorics (math.CO)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 52A20, 52A30, 46 G 10

description: Let $Q$ be the unit cube in $\mathbb{R}^n$ and $H$ a hyperplane thru the Origin. The intersection $H\cap Q$is called (central) Cube slice and was investigated by Henesley, Vaaler, Ball and others. A zonoid is the range of a measure into $R^n$. Our interest is : When is a cube slice a zonoid? We only give an example of a cube slice in $\mathbb{R}^4$ that is not a zonoid. We also give examples ofslices that are zonoids. For ex let H: $ax + y +z + t =0$h If $ a\ge 3$ then the slice is a zonoid( zonotope) Otherwise it isnot ,
description: 12 pages
Quantification of arsenic, lead, mercury and cadmium in newborn dried blood spots
Creators: name: McGee, John K.
name: Olshan, Andrew F.
name: Ghio, Andrew J.
name: Funk, William E.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: AbstractExposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public health departments to screen for inherited metabolic errors and other disorders, are routinely archived and can be used for exposure assessment. Here we report an improved method for quantifying arsenic, lead, mercury and cadmium in newborn DBS to facilitate epidemiologic research on the health effects of early exposures to toxic metals.
(103124) Frederick Roy Ashmead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
MPEC 2023-T212 : 2010 GN67
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
Single Transverse Spin Asymmetries in Semi-inclusive Deep Inelastic Scattering in a Spin-1 Diquark Model
Creators: name: Kumar, Narinder
name: Dahiya, Harleen
Publisher: name: arXiv
Year: 2015
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The observed results for the azimuthal single spin asymmetries (SSAs) of the proton, measured in the semi-inclusive deep inelastic scattering (SIDIS), can be explained by the final-state interaction (FSI) from the gluon exchange between the outgoing quark and the target spectator system. SSAs require a phase difference between two amplitudes coupling the target with opposite spins to the same final state. We have used the model of light front wave functions (LFWFs) consisting of a spin-$\frac{1}{2}$ system as a composite of a spin-$\frac{1}{2}$ fermion and a spin-1 vector boson to estimate the SSAs. The implications of such a model have been investigated in detail by considering different coupling constants. The FSIs also produce a complex phase which can be included in the LFWFs to calculate the Sivers and Boer-Mulders distribution functions of the nucleon.
description: 23 pages, 4 figures. To appear in Eur. Phys. J. A
(103123) Mary Elizabeth Thompson
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103122) George Frederick Bromhead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103121) Annie Bromhead
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103119) Thomas Holmes
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
MPEC 2023-T213 : 2012 VO6
Creators: name: Minor Planet Center Staff
Publisher: name: The Minor Planet Center
Year: 2023
Subjects: subject: Small Solar System bodies
valueUri: http://astrothesaurus.org/uat/1469

description: The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements.  They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
(103118) Sarah [Holmes]
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.
(103116) Sarah Isabella Holmes
Creators: name: Professions, Victorian
Publisher: name: University of Oxford
Year: 2022
Subjects: subject: 220201 Business and Labour History
subject: FOS: Philosophy, ethics and religion
subject: History
subject: 140203 Economic History
subject: FOS: Economics and business

description: This three-year research project began in January 2014 and investigated whether, during the Victorian period, the professions formed a distinct self-sustaining social group with its own mores and values. The project looked at 16,000 individuals drawn from census data for Alnwick, Brighton, Bristol, Dundee, Greenock, Leeds, Merthyr Tydfil, Morpeth, and Winchester. The research project was funded by the UK Economic & Social Research Council and was based at the Universities of Oxford and Northumbria.