cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
title: Infezione congenita da citomegalovirus ed ipoacusia: screening mirato o screening universale?
title: Audiologia e Foniatria
titleType: Subtitle
Creators: name: V. Gambacorta
name: G. Ricci
name: F. Korsch
name: E. Orzan
Publisher: name: Padova University Press
Year: 2024
Subjects: CMV congenito
ipoacusia
screening universale

description:
Razionale - L’infezione da citomegalovirus (CMV) è l’infezione congenita più comune, con una prevalenza dello 0,3-1,2% nei paesi industrializzati. Il CMV è anche la causa non genetica più frequente di ipoacusia permanente nei bambini, con una incidenza dello 0,2-2%. Non è stato istituito un programma di screening universale perché non esiste una terapia prenatale o un vaccino per contrastare il CMV e molti pazienti con CMV congenito (cCMV) non mostrano sequele anche in assenza una terapia specifica. In caso di fallimento dello screening audiologico neonatale, i protocolli attualmente in uso includono un test su campione biologico per cercare il cCMV. L’obiettivo di questo articolo è analizzare i pro e i contro dei vari approcci di screening per il cCMV e fornire una panoramica critica dell’argomento utilizzando la letteratura più recente e analizzando i risultati preliminari di uno studio pilota condotto presso l’università degli studi di Perugia in cui una coorte di pazienti è stata sottoposta a screening universale del cCMV. Materiali e metodi - È stata effettuata una revisione narrativa della letteratura scientifica più recente nazionale e internazionale sullo screening del cCMV. Risultati - Le attuali procedure includono la ricerca del CMV nelle urine o nella saliva entro le tre settimane di vita, in seguito a un esito positivo (refer) allo screening audiologico neonatale nell’ambito dei programmi di screening e identificazione precoce delle ipoacusie neonatali. Questo metodo consente di identificare rapidamente l’infezione da CMV nei neonati con ipoacusia isolata già presente alla nascita. Tuttavia, non è possibile identificare la percentuale di ipoacusia correlata al CMV che si verifica post-natale o tardivamente nell’infanzia. Un screening universale del cCMV combinato con uno screening audiologico sarebbe vantaggioso per identificare tutti i bambini con infezione da cCMV, incluso il 10%-15% dei bambini asintomatici alla nascita che potrebbero subire danni uditivi permanenti in seguito. Una delle maggiori sfide per la creazione di uno screening universale del cCMV è la mancanza di chiarezza sui costi di applicazione e sulla sensibilità e sulla specificità del test CMV. Conclusioni - Sono necessarie strategie volte ad individuare i bambini con infezione congenita da CMV che possono sviluppare ipoacusia a insorgenza tardiva. È auspicabile l’istituzione di uno screening neonatale universale per garantire che i bambini affetti da cCMV vengano riconosciuti tempestivamente e sottoposti ad una stretta sorveglianza audiologica e ad un trattamento precoce alla comparsa dei primi sintomi uditivi.
Andesianellus minutus Anderson and Morrone 1996
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Andesianellus
Andesianellus minutus

description: Andesianellus minutus Anderson and Morrone, 1996
 Andesianellus minutus Anderson and Morrone, 1996: 264 (type locality: Peru: Cuzco Department, Pillahuata, Manu Road, km 128; type material: H: FMNH and P: 1 CMNCH and 1 FMNH).
 Distribution. Southern Peru (Anderson and Morrone, 1996).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 14, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
‘I never thought exercise could help improve my sleep’: experiences of people with rheumatoid arthritis on the impact of an 8-week walking-based exercise intervention in improving their sleep
Creators: name: McKenna, Sean
name: Larkin, Louise
name: DONNELLY, ALAN
name: Esbensen, Bente Appel
name: Ng, Wan Lin
name: Maqsood Anjum, Aqeel
name: Fraser, Alexander
name: Kennedy, Norelee
Publisher: name: University of Limerick
Year: 2024
Subjects: classificationCode: 42
subject: Health sciences
subject: FOS: Health sciences

description: Objective: The purpose of this study was to explore the experiences of people with RA of participating in an exercise intervention to improve their sleep. Methods: Using a qualitative descriptive design, semi-structured face-to-face interviews were conducted with 12 people with RA who had completed an 8-week walking-based exercise intervention to improve their total sleep time, sleep quality and sleep disturbance. Data were analysed using thematic analysis. Results: Four themes were generated: positive impact of exercise on participants’ sleep (‘I really didn’t think any type of exercise would help me sleep better, if I’m honest’); positive experiences of the exercise intervention (‘I learnt so much regarding walking that I didn’t even think about’); clear mental health benefits (‘If you don’t sleep well then it will have a knock-on effect to your mental health’); and achieving empowerment and ownership when exercising (‘I feel empowered now and confident that I’m not doing harm to myself’). Conclusion: The findings demonstrated that participants had not expected exercise to improve their sleep. Although there is a growing consensus that exercise will benefit sleep and mitigate some disease symptoms, research is severely lacking in people with RA.
Phenomenology of the new light Higgs bosons in Gildener-Weinberg model
Creators: name: Lane, Kenneth
name: Pilon, Eric
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Gildener-Weinberg (GW) models of electroweak symmetry breaking are especially interesting because the low mass and nearly Standard Model couplings of the $125\,{\rm GeV}$ Higgs boson, $H$, are protected by approximate scale symmetry. Another important but so far under-appreciated feature of these models is that a sum rule bounds the masses of the new charged and neutral Higgs bosons appearing in {\em all} these models to be below about $500\,{\rm GeV}$. Therefore, they are within reach of LHC data currently or soon to be in hand. Also so far unnoticed of these models, certain cubic and quartic Higgs scalar couplings vanish at the classical level. This is due to spontaneous breaking of the scale symmetry. These couplings become nonzero from explicit scale breaking in the Coleman-Weinberg loop expansion of the effective potential. In a two-Higgs doublet GW model, we calculate $λ_{HHH} \simeq 2(λ_{HHH})_{\rm SM} = 64\,{\rm GeV}$. This corresponds to $σ(pp \to HH) \cong 15$--$20\,{\rm fb}$, its {\em minimum} value for $\sqrt{s} = 13$--$14\,{\rm TeV}$ at the LHC. It will require at least the $27\,{\rm TeV}$ HE-LHC to observe this cross section. We also find $λ_{HHHH} \simeq 4(λ_{HHHH})_{\rm SM} = 0.129$, whose observation in $pp \to HHH$ requires a $100\,{\rm TeV}$ collider. Because of the above-mentioned sum rule, these results apply to {\em all} GW models. In view of this unpromising forecast, we stress that LHC searches for the new relatively light Higgs bosons of GW models are by far the surest way to test them in this decade.
description: 25 pages, 5 figures, 1 table; Completely revised version of arXiv:1909.0211, including new title, new abstract and substantial new material and focus on the LHC signals of the Higgs bosons in a 2HDM Gildener-Weinberg model. Version to be published in Physical Review D
The potential for improvement in on-road truck fuel economy: evidence from the VIUS
Creators: name: He, Jen
name: Leard, Benjamin
name: Linn, Joshua
name: McConnell, Virginia
name: He, Jen
name: Leard, Benjamin
name: Linn, Joshua
name: McConnell, Virginia
Publisher: name: Unknown
Year: 2016
Subjects: Environmental Economics and Policy
Research and Development/Tech Change/Emerging Technologies
Resource /Energy Economics and Policy

description: This study looks at the evidence about fuel economy and other truck attributes from VIUS, and provides implications for a dynamic baseline of improvements in fuel economy. We discuss the engine technologies and vehicle designs that potentially improve truck fuel economy. The combined effects of these advances are estimated as technological progress in our specifications. The rich information from VIUS about vehicle characteristics equips us to estimate the trade-off effects – how vehicle weight and engine power affect fuel economy.
MOESM2 of Neurocognitive outcome of school-aged children with congenital heart disease who underwent cardiopulmonary bypass surgery: a systematic review protocol
Creators: name: Feldmann, Maria
name: Ullrich, Cinzia
name: CĂŠlina Bataillard
name: Knirsch, Walter
name: Gosteli-Peter, Martina
name: Latal, Beatrice
name: Held, Ulrike
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Sociology
subject: FOS: Sociology
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: Additional File 2: _20190819_revised.docx. Medline search strategy (DOCX 21 kb)
title: Infezione congenita da Citomegalovirus: updates.
title: Audiologia e Foniatria
titleType: Subtitle
Creators: name: Costanza Paramithiotti
name: Giovanni Chiaffoni
name: Giuseppe Banderali
Publisher: name: Padova University Press
Year: 2024
Subjects: Citomegalovirus
CMV
congenital infection
hearing loss
valganciclovir
infezione congenita
ipoacusia

description:
Congenital Cytomegalovirus (CMV) infection still represents a disease of great impact on individual and public health in the paediatric age. It has an estimated global prevalence of 0.64%, with the risk of developing permanent sequelae in 20% of patients. It is the leading cause of acquired sensorineural hearing loss and is frequently related to visual and neurodevelopmental impairments. In the majority of cases (85-90%) congenital CMV infection is asymptomatic at birth, with 10-15% of cases presenting symptoms mainly affecting the central nervous system. However, in asymptomatic cases, late onset manifestations are possible even years later, the most frequent one being sensorineural hearing loss. The European Congenital Cytomegalovirus Initiative has recently published a revision of the recommendations on management of congenital CMV infection4, introducing antiviral therapy in pregnancy as an important tool for prevention of vertical transmission. Serological analysis (CMV-IgG and IgM) should be performed as early as possible during pregnancy, in order to start antiviral therapy with valacyclovir in case of primary infection acquired during the first trimester. Moreover, it has been shown that the risk for long-term sequelae for newborns is higher when the infection is acquired during the first trimester of pregnancy, becoming close to zero in case of infection during the second and third trimesters. Pharmacological therapy with valganciclovir is now recommended not only for newborns with moderate to severe manifestations, but also for those presenting isolated sensorineural hearing loss. Treatment should be started within the first month of life. The importance of multidisciplinary follow up until school age is also underlined.
Family Unification, Exotic States and Magnetic Monopoles
Creators: name: Kephart, Thomas W.
name: Shafi, Qaisar
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The embedding in SU(4)xSU(3)xSU(3) of the well studied gauge groups SU(4)xSU(2)xSU(2) and SU(3)xSU(3)xSU(3) naturally leads to family unification as opposed to simple family replication. An inescapable consequence is the predicted existence of (exotic)color singlet states that carry fractional electric charge. The corresponding magnetic monopoles carry multiple Dirac magnetic charge, can be relatively light (\sim 10^{7}-10^{13}GeV), and may be present in the galaxy not far below the Parker bound.
description: 10 pages, Latex
Experimental Demonstration of Eight-dimensional Modulation Formats for Long-haul Optical Transmission
Creators: name: van der Heide, Sjoerd
name: Chen, Bin
name: Hout, Menno van den
name: Hafermann, Hartmut
name: Koonen, Ton
name: Alvarado, Alex
name: Okonkwo, Chigo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Signal Processing (eess.SP)
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: Two novel 5.5 bit/4D modulation formats are experimentally demonstrated to transmit over 9680 km of SSMF. A reach increase of 29.4% over the 6 bit/4D PM-8QAM is shown. Furthermore, increased nonlinear tolerance with respect to PM-8QAM is shown.
description: ECOC (European Conference on Optical Communication) 2019 submission. Accepted for oral presentation at 11:15 on 2019/09/25 in the "Modulation and Coding" session
Quality of some hybrid seeds of rice and control of seed borne fungi in Bangladesh
Creators: name: Akter, M. A.
name: Hossain, I
name: Akter, M. A.
name: Hossain, I
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: Hybrid Rice
subject: Seed purity
subject: Seed borne pathogens
subject: Botanical extract
subject: Biological control agent

description: A study was conducted for assessing quality of 15 hybrid rice seed samples and management of seed borne fungal pathogens by three selected chemicals namely Bavistin (0.3%), Thiovit (0.3%) and Provax (0.3%) along with two botanicals such as: Garlic extract (Allium sativum) (1:1) and Allamanda leaf extract (Allamanda cathartica) (1:1) and a bio-control agent BAU-Biofungicide @ 3% (Trichoderma based preparation) at Seed Pathology Centre, MS Laboratory and Eco-friendly Plant Disease Management Laboratory of Department of Plant Pathology, Bangladesh Agricultural University, Mymensingh during 2013-14. Collected seed samples were categorized by dry inspection as apparently healthy seed (35.7 to 85.7%), discolored seed (0.5 to 22.2%), spotted seed (0.7 to 8.1%), broken seed (0.4 to 44.3%), deformed seed (0 to 1.4%), insect damaged seed (0 to 4.9%), chaffy seed (0 to 1.1%), varietal mixture (0 to 7.2%) and inert matter (0 to 2.6%). In case of purity analysis, pure seed ranged from 92.86 to 100.00%, other seeds 0 to 7.14% and inert matter 0 to 2.59%. 100% pure seed was recorded in Agomoni, Jagoron, Gold, Suborno, Hira-1, Hira-2, Hira-4 and Hira-6 collected from Ispahani Agro. Ltd., BRAC, Lal Teer seed Co. Ltd. and Supreme seed Co. Ltd. Seed treatment with Allamanda leaf extract, Provax and BAU-Biofungicide increased germination, Vigor index and decreased prevalence of seed borne fungi. Among the treatments, biofungicide increased germination 54.39% in blotter method and 89.58% in tray method over control. In addition, BAU-Biofungicide increased up to 713.78% vigor index over untreated control. BAU-Biofungicide may be recommended for controlling seed borne fungal pathogens of hybrid rice in Bangladesh.
Contextualização Histórica, Sócio Econômica e das Formas de Intervenções Públicas do Vale do Jequitinhonha: Um panorama do início dos anos dois mil
Creators: name: Araújo, Elana Fernandes
name: De Castro, Charles Alves
Publisher: name: figshare
Year: 2021
Subjects: subject: 160808 Sociology and Social Studies of Science and Technology
subject: FOS: Sociology
subject: Economics
subject: 140203 Economic History
subject: FOS: Economics and business
subject: 140202 Economic Development and Growth
subject: 160699 Political Science not elsewhere classified
subject: FOS: Political science
subject: 160605 Environmental Politics
subject: 160603 Comparative Government and Politics

description: A mesorregião do Jequitinhonha ou Vale do Jequitinhonha, situada no nordeste de Minas Gerais, é uma região povoada por aproximadamente um milhão de pessoas. Divididas em 51 municípios - somando quase 14,5% do total de municípios do Estado de Minas Gerais - há anos vem se tornando um espaço marcado por diversas formas de exclusão social. Partindo da literatura que busca compreender de que forma as mudanças do papel do Estado Nacional após a década de 1990 condicionaram o direcionamento das políticas públicas, em especial, das políticas de transferência de renda, este trabalho procura buscar evidências das mudanças nos indicadores socioeconômicos dessa região. Este artigo busca entender o panorama do início dos anos dois mil da região, reforçando a análise com o entendimento do seu contexto histórico e regional.
Andesianellus tricarinatus Anderson and Morrone 1996
Creators: name: Morrone, Juan J.
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Coleoptera
Curculionidae
Andesianellus
Andesianellus tricarinatus

description: Andesianellus tricarinatus Anderson and Morrone, 1996
 Andesianellus tricarinatus Anderson and Morrone, 1996: 266 (type locality: Peru: Cuzco Department, Consuelo, Manu Road, 165 km; type material: H: FMNH and P: 4 CMNC and FMNH).
 Distribution. Southern Peru (Anderson and Morrone, 1996).
description: Published as part of Morrone, Juan J., 2011, Annotated checklist of the tribe Listroderini (Coleoptera: Curculionidae: Cyclominae) 3119, pp. 1-68 in Zootaxa 3119 (1) on page 15, DOI: 10.11646/zootaxa.3119.1.1, http://zenodo.org/record/5246257
Ceiling Interaction: Properties, Usage Scenarios, and a Prototype
Creators: name: Wimmer, Raphael
name: Bazo, Alexander
name: Heckner, Markus
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2013
Subjects: subject: 004 Informatik

description: We propose utilizing the ceiling of personal and oﬃce spaces as an additional interactive display for both single-user applications and collaboration. Ceilings oﬀer a display space that is unobtrusive, allows unobstructed viewing from many positions, and allows direct mapping to the room below. Previous research on ceilings as interactive displays has focused on providing ambient information. We argue that interactive ceilings are even better suited for supporting collaboration between persons in a shared room, and as an unobtrusive extension of a user’s desktop. Also, interactive ceilings can display status information directly above persons or objects on the ﬂoor. We discuss perceptual and ergonomic properties of interactive ceilings, propose concrete applications that beneﬁt from interactive ceilings, describe a rear-projected prototype that we built with a size of 1.82 x 1.02 m, and present the design of a study investigating perceptual limitations of interactive ceilings.
Quantification of thermally-driven flows in microsystems using Boltzmann equation in deterministic and stochastic contexts
Creators: name: Jaiswal, Shashank
name: Pikus, Aaron
name: Strongrich, Andrew
name: Sebastião, Israel B.
name: Hu, Jingwei
name: Alexeenko, Alina A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Physics (physics.comp-ph)
subject: FOS: Physical sciences
subject: 76P05, 82B40, 82C40, 82D05, 35Q20, 65T50, 65M60, 65M70, 65Y05

description: When the flow is sufficiently rarefied, a temperature gradient, for example, between two walls separated by a few mean free paths, induces a gas flow---an observation attributed to the thermo-stress convection effects at microscale. The dynamics of the overall thermo-stress convection process is governed by the Boltzmann equation---an integro-differential equation describing the evolution of the molecular distribution function in six-dimensional phase space---which models dilute gas behavior at the molecular level to accurately describe a wide range of flow phenomena. Approaches for solving the full Boltzmann equation with general inter-molecular interactions rely on two perspectives: one stochastic in nature often delegated to the direct simulation Monte Carlo (DSMC) method; and the others deterministic by virtue. Among the deterministic approaches, the discontinuous Galerkin fast spectral (DGFS) method has been recently introduced for solving the full Boltzmann equation with general collision kernels, including the variable hard/soft sphere models---necessary for simulating flows involving diffusive transport. In this work, the deterministic DGFS method; Bhatnagar-Gross-Krook (BGK), Ellipsoidal statistical BGK, and Shakhov kinetic models; and the widely-used stochastic DSMC method, are utilized to assess the thermo-stress convection process in MIKRA---Micro In-Plane Knudsen Radiometric Actuator---a microscale compact low-power pressure sensor utilizing the Knudsen forces. BGK model under-predicts the heat-flux, shear-stress, and flow speed; S-model over-predicts; whereas ESBGK comes close to the DSMC results. On the other hand, both the statistical/DSMC and deterministic/DGFS methods, segregated in perspectives, yet, yield inextricable results.
title: Vaccino anti CMV a mRNA: studi di efficacia e sicurezza.
title: Audiologia e Foniatria
titleType: Subtitle
Creators: name: Giancarlo Icardi
name: Matilde Ogliastro
Publisher: name: Padova University Press
Year: 2024
Subjects: Cytomegalovirus
CMV
HCMV
vaccine
mRNA vaccine
efficacy
safety
Citomegalovirus
vaccino
vaccino a mRNA
efficacia
sicurezza

description:
Human cytomegalovirus (HCMV) is a globally widespread virus, with a prevalence ranging from 40-80% in industrialized countries and nearly 100% in developing countries. While often asymptomatic in immunocompetent individuals, HCMV infection can lead to severe diseases in immunocompromised patients. Furthermore, when contracted during pregnancy, HCMV is one of the leading causes of congenital birth defects. Close contact with young children is a major risk factor for maternal HCMV infection, and proper hygiene practices can significantly reduce this risk. Recent research efforts have focused on developing a vaccine to prevent intrauterine CMV transmission. The use of mRNA technology represents a promising new direction, exemplified by the mRNA-1647 vaccine, which encodes the pentameric complex and gB antigen through 6 mRNA sequences. Phase 1 and 2 trials have demonstrated the safety, reactogenicity, and immunogenicity of the mRNA-1647 vaccine in both seropositive and seronegative adults. Results show that the vaccine induces a robust immune response, with neutralizing antibodies remaining elevated for up to 18 months post-vaccination. Currently, a Phase 3 trial is underway to evaluate the vaccine’s efficacy, safety, and immunogenicity in female participants aged 16 to 40 years. The mRNA-1647 vaccine shows promising results, and if Phase 3 concludes successfully, it could pave the way for future approval.
Effects of vermicompost on growth and leaf biomass yield of stevia and post harvest fertility status of soil
Creators: name: Zaman, M. M.
name: Chowdhury, M. A. H.
name: Islam, M. R.
name: Uddin, M. R.
name: Zaman, M. M.
name: Chowdhury, M. A. H.
name: Islam, M. R.
name: Uddin, M. R.
Publisher: name: Unknown
Year: 2015
Subjects: subject: Agricultural and Food Policy
subject: Stevia
subject: Vermicompost
subject: Leaf biomass yield
subject: Soil fertility

description: In view of the growing awareness about eco-friendly organic farming, vermicompost (VC) could be a very good option for increasing crops yield. The organic carbon in VC releases nutrients slowly and steadily into the system and enables the plant to absorb these nutrients. To assess the effect of VC on soil fertility, growth and yield of stevia in acid and non-calcareous soils, an experiment was undertaken in the net house of the Department of Agricultural Chemistry, Bangladesh Agricultural University, Mymensingh, during February to May, 2012. Four levels of VC viz. 0, 5, 7.5 and 10 t ha-1 in two contrasting soils (Acid and Non-calcareous) were examined following CRD with three replications. Growth and yield attributes such as plant height, branch and leaf number, leaf area, fresh and dry weight of leaves were significantly influenced by different levels of VC. All the plant parameters increased with the advancement of growth period as well with increased rate of VC up to 7.5t ha-1 and then declined with further additions. The leaf biomass yield was 335% and 338% higher in acid soil and in non-calcareous soil, respectively over control. The overall performance of non-calcareous soil was superior to acid soil in terms of both plant and soil parameters studied. The acidity of both soils significantly decreased with the increased application of VC ranging from 4.9 to 5.7 in acid soil and 6.5 to 7.2 in non-calcareous soil. Total N, available P, exchangeable K, Ca, Mg, available S, Zn, B were also significantly increased with the increased levels of VC up to its highest level (VC @ 10t ha-1) in both soils. Thus the results suggest that VC @ 7.5t ha-1 should be applied for getting maximum leaf biomass yield of stevia and 10t ha-1 for increasing the fertility of both soils under the agro-climatic conditions of the studied area.
The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort
Creators: name: Klatte, Tobias
name: Gallagher, Kevin M.
name: Afferi, Luca
name: Volpe, Alessandro
name: Kroeger, Nils
name: Ribback, Silvia
name: McNeill, Alan
name: Riddick, Antony C. P.
name: Armitage, James N.
name: ‘Aho, Tevita F.
name: Eisen, Tim
name: Fife, Kate
name: Bex, Axel
name: Pantuck, Allan J.
name: Stewart, Grant D.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Research Article
Recurrence
Papillary
Prognosis
Adjuvant
Surveillance
Localised

description: Abstract: Background: The current World Health Organization classification recognises 12 major subtypes of renal cell carcinoma (RCC). Although these subtypes differ on molecular and clinical levels, they are generally managed as the same disease, simply because they occur in the same organ. Specifically, there is a paucity of tools to risk-stratify patients with papillary RCC (PRCC). The purpose of this study was to develop and evaluate a tool to risk-stratify patients with clinically non-metastatic PRCC following curative surgery. Methods: We studied clinicopathological variables and outcomes of 556 patients, who underwent full resection of sporadic, unilateral, non-metastatic (T1–4, N0–1, M0) PRCC at five institutions. Based on multivariable Fine-Gray competing risks regression models, we developed a prognostic scoring system to predict disease recurrence. This was further evaluated in the 150 PRCC patients recruited to the ASSURE trial. We compared the discrimination, calibration and decision-curve clinical net benefit against the Tumour, Node, Metastasis (TNM) stage group, University of California Integrated Staging System (UISS) and the 2018 Leibovich prognostic groups. Results: We developed the VENUSS score from significant variables on multivariable analysis, which were the presence of VEnous tumour thrombus, NUclear grade, Size, T and N Stage. We created three risk groups based on the VENUSS score, with a 5-year cumulative incidence of recurrence equalling 2.9% in low-risk, 15.4% in intermediate-risk and 54.5% in high-risk patients. 91.7% of low-risk patients had oligometastatic recurrent disease, compared to 16.7% of intermediate-risk and 40.0% of high-risk patients. Discrimination, calibration and clinical net benefit from VENUSS appeared to be superior to UISS, TNM and Leibovich prognostic groups. Conclusions: We developed and tested a prognostic model for patients with clinically non-metastatic PRCC, which is based on routine pathological variables. This model may be superior to standard models and could be used for tailoring postoperative surveillance and defining inclusion for prospective adjuvant clinical trials.
Integrated effects of poultry manure and chemical fertilizer on the growth, leaf yield and stevioside content of stevia
Creators: name: Zaman, M. M.
name: Chowdhury, M. A. H
name: Chowdhury, Tanzin
name: Zaman, M. M.
name: Chowdhury, M. A. H
name: Chowdhury, Tanzin
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: Stevia
subject: Poultry manure
subject: Chemical fertilizer
subject: Leaf yield
subject: Stevioside content
subject: Acid and non-calcareous soil

description: Stevia is important for its leaves which are used as non calorie sweetener and also in many therapeutic applications including diabetes. The present investigation was carried out in the net house of the Department of Agricultural Chemistry, Bangladesh Agricultural University, Mymensingh to investigate the integrated effects of poultry manure (PM) and chemical fertilizer (CF) on the growth, leaf biomass yield and stevioside content of stevia grown in two contrasting soils (acid and non-calcareous) of Bangladesh. Six combinations of PM and CF viz. PM0+CF0, PM0+CF100, PM3+CF50, PM3+CF75, PM5+CF50, PM5+CF75 were used. The study revealed that PM along with different percentages of chemical fertilizers exerted significant influence on the growth, leaf yield and stevioside content of stevia. The highest values of all the parameters except stevioside were found from the plant receiving PM @ 3 t ha-1 along with 75% CF. The leaf biomass yield was 1088% and 867% higher in acid soil and non-calcareous soil, respectively, over control. Stevioside content was increased with increasing the levels of PM up to 5 t ha-1 and also with the advancement of growth period from 30 to 60 days after planting. The highest amount of stevioside (10.45%) was detected in the leaves of the plant that received PM @ 5 t ha-1 along with 75% CF at 60 DAP in acid soil and it was 9.11% in non-calcareous soil at the same period. The lowest values of all the parameters including stevioside content were obtained from the plant which received neither PM nor CF. Considering the overall performance, farmers may be advised to cultivate stevia in acid soil applying PM @ 3 t ha-1 along with 75% chemical fertilizer to boost up the production of stevia under the agro-climatic condition of the study area in the context of Bangladesh.
Additional file 1 of In silico evaluation of a targeted metaproteomics strategy for broad screening of cellulolytic enzyme capacities in anaerobic microbiome bioreactors
Creators: name: Villalobos Solis, Manuel I.
name: Chirania, Payal
name: Hettich, Robert L.
Publisher: name: figshare
Year: 2022
Subjects: subject: Microbiology
subject: FOS: Biological sciences

description: Additional file 1: Figure S1. Example showing the process to select the minimum number of unique tryptic peptides and their associated number of protein seeds in different GH families. (A) Example of a starting list of seven proteins in a GH family each containing different numbers of peptides that are unique to a particular GH family and which can be shared or be unique among the proteins in that family. (B) The script first assembles groups of peptides and proteins and then orders them based on peptides capturing the greatest number of proteins. In this example, peptide 1 is shared among the majority of proteins in the input list. This group of 4 proteins that have peptide 1 is then compared to protein groups captured by other peptides. Based on this comparison, if a protein that has peptide 1 is found in a group with fewer number of proteins, the protein is removed from the list. In this case, proteins are removed from peptides 2 and 3, while peptide 4 loses all its proteins and is removed from further analysis. This iteration is repeated now with the second largest group of proteins sharing a peptide, which in this case is peptide 5. (C) Following this example, the final minimum list of “unique” peptides will have peptide 1 capturing four proteins (A, D, E, F), peptide 5 capturing two proteins (C, G) and either peptides 3 or 6 capturing one protein (B). Figure S2. Number of high quality (HQ) & medium high quality (MHQ) MAGs identified in the biogas microbiome project. MAGs were assigned to different phyla based on the tiered taxonomic assignment strategy described in the original paper by Campanaro et al., 2020. The inset shows the total percentages of MAGs per superkingdom. N/A- MAGs not assigned at the phylum level. Figure S3. Distribution of the sizes of the predicted proteomes from the HQ & MHQ quality MAGs from the biogas microbiome project. Coding sequences (CDS) were annotated using Prodigal v2.6.2. Figure S4. The identified tryptic peptides did not map to catalytic regions of the proteins. The figure shows examples of two GH2 protein sequences in the biogas microbiome dataset analyzed with InterProScan. According to our bioinformatic analysis, the unique tryptic peptides TSHYPNDPR and WYPGAGLYR are found in 51 and 25 different GH2 proteins, respectively. These numbers were among the highest numbers of proteins covered by single peptides in this family. As observed, these two peptides mapped to different GH2 family domains (highlighted in blue and purple colors). No tryptic peptides matching our selection criteria mapped to the active site motif in GH2 proteins (in yellow, PS00608) which is used as the signature pattern to classify GH proteins into this family. Table S4. Description of EC numbers shown in Fig. 4.
QCD corrections to Associated t-tbar-H production at the Tevatron
Creators: name: Reina, L.
name: Dawson, S.
name: Wackeroth, D.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present in detail the calculation of the O(alpha_s^3)inclusive total cross section for the process (p pbar-> t tbar h) in the Standard Model, at the Tevatron center-of-mass energy sqrt(s_H)=2 TeV. The next-to-leading order QCD corrections significantly reduce the renormalization and factorization scale dependence of the Born cross section. They slightly decrease or increase the Born cross section depending on the values of the renormalization and factorization scales
description: 46 pages, 13 figures
title: Diagnosi e gestione del CMV in gravidanza alla luce delle nuove evidenze.
title: Audiologia e Foniatria
titleType: Subtitle
Creators: name: Fabio Ghezzi
name: Antonella Cromi
Publisher: name: Padova University Press
Year: 2024
Subjects: Citomegalovirus
gravidanza
congenito
screening
terapia
valaciclovir

description:
Negli ultimi anni sono stati compiuti importanti progressi conoscitivi sull’infezione congenita da CMV (cCMV) a seguito di infezione primaria materna. Innanzitutto, è stata dimostrata l’efficacia del trattamento con valaciclovir nel prevenire la trasmissione verticale dopo diagnosi di infezione primaria da CMV in epoca periconcezionale o nel primo trimestre di gravidanza. Inoltre, si sono accumulate crescenti evidenze del fatto che il rischio di sequele maggiori è limitato all’infezione materna nel primo trimestre di gravidanza. Alla luce delle migliori evidenze disponibili, sono state riviste le raccomandazioni per la gestione prenatale della cCMV , sia in termini di oferta dello screening sierologico universale in gravidanza, sia di terapia per la prevenzione della trasmissione transplacentare del CMV. Il ruolo del valaciclovir nel miglioramento degli esiti perinatali e nella riduzione del rischio di anomalie strutturali fetali, infezione sintomatica e compromissione cognitiva nei feti con infezione congenita confermata da CMV rimane da chiarire. Parimenti, se l’efficacia del valacicovir sia confermata anche per le infezioni avvenute in epoca periconcezionale e le infezioni materne secondarie non è al momento noto.
Comparative efficacy of different botanicals and chemical insecticides for controlling rice stem borer
Creators: name: Majlish, A. K.
name: Uddin, M. M.
name: Jahan, M
name: Rahman, M.M.
name: Majlish, A. K.
name: Uddin, M. M.
name: Jahan, M
name: Rahman, M.M.
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: Efficacy
subject: Botanical
subject: Chemical insecticide
subject: Control
subject: Rice
subject: Stem borer

description: An experiment was carried out in the field laboratory, Department of Entomology, Bangladesh Agricultural University to find out the efficacy of different botanicals and chemical insecticides against rice stem borer during the period from July to December 2013. The treatments included Neem oil, Mahogany oil, combination of Neem and Mahogany oil, Bishkatali leaf extract, Lantana leaf extract, combination of Bishkatali and Lantana leaf extract, Convoy 25EC, Biesterthoate 40EC, Biesteren 5G and Diatone 10G. The efficacies of treatments were evaluated based on the percent dead heart and white head resulted by rice stem borer infestation at vegetative and reproductive stages, respectively. The efficacies of treatments were varied significantly against the rice stem borers. Among the selected botanicals, Neem + Mahogany oil followed by Bishkatali leaf extract performed best and Bishkatali + Lantana followed by Lantana leaf extract and leaf extract were least effective to reduce dead heart as well as white head at different counting. Similarly, combination of Neem and Mahogany oil gave the maximum yield among the selected botanicals. Diatone 10G showed the best performance to reduce percent dead and white head among the selected chemical insecticides and gave maximum yield among different chemical insecticides. On the other hand, Convoy 25EC was the least effective to control dead heart and white head infestation with yield. Therefore, Neem + Mahogony oil and Diatone 10G were the best to control rice stem borer and to increase the yield of rice grain.
Diagnosis and prescription for Cercospora leaf spot of chilli
Creators: name: Islam, M. S.
name: Fatema, K.
name: Alam, K. M. B.
name: Meah, M. B
name: Islam, M. S.
name: Fatema, K.
name: Alam, K. M. B.
name: Meah, M. B
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: Diagnosis
subject: Prescription
subject: Leaf spot
subject: Chilli

description: The experiments were carried out during 2009 to 2013 on diagnosis and prescriptions for management of Cercospora leaf spot of chilli. The studies were undertaken in 250 grower’s field of five upazillas viz. Mymensingh sadar, Kushtia sadar, Kumarkhali, Chandina and Sher-e-Bangla Nagar. The highest disease incidence (38.6%) and severity (17.4%) of Cercospora leaf spot of chilli was recorded. Cercospora capsici produced leaf spot of chilli. The prescription given by Plant Disease Diagnostic Clinic (PDDC) was effective in the farmer’s field against the disease. Cercospora leaf spot of chilli is the most important diseases of spices in Bangladesh as the diseases significantly reduce the quality and yield. Prescription was Bavistin-50 DF @ 1g/l sprayed 4 times at 15 days interval for management of Cercospora leaf spot of chilli. The practices reduced the incidence by 72.82%, severity by 65.60%. The yield increased by 35.11%. Benefit cost ratio (BCR) was 3.34.
The UV spectral slope beta and stellar population of most active star-forming galaxies at z~4
Creators: name: Yamanaka, Satoshi
name: Yamada, Toru
Publisher: name: arXiv
Year: 2019
Subjects: subject: Astrophysics of Galaxies (astro-ph.GA)
subject: FOS: Physical sciences

description: We investigate the stellar population of star-forming galaxies at $z \sim 4$ by focusing on their slope of rest-frame ultraviolet (UV) continuum, $β$ where $f_λ \propto λ^β$. We investigate the sample of bright Lyman Break Galaxies (LBGs) with $i' \leq 26.0$ in the Subaru/XMM-Newton Deep Survey field by using the SED fitting analysis. We find that the apparently redder ($β_{\mathrm{obs}} > -1.73$) LBGs tend to be dusty ($\mathrm{Av} > 1.0$), have the young stellar population ($β_{\mathrm{int}} < -2.42$), and the intrinsically active star-forming galaxies (SFR $\gtrsim$ a few $\times 10^{2}$ $\mathrm{M_{\odot}} \mathrm{yr^{-1}}$). It means that a significant fraction of the UV-selected LBGs at $z \sim 4$ is on-going active and dust obscured star-forming galaxies. We compare the IR to UV luminosity ratio assuming the dust attenuation laws with the sub-millimeter observations from previous works. The result suggests that the Calzetti-like dust attenuation law is preferable for the active and dusty star-forming LBGs at $z = 4$. We also find that an extrapolation of the $β_{\mathrm{int}}$-$M_{\mathrm{UV,int}}$ relation toward the fainter magnitude range below our sample magnitude limit intersects the $β_{\mathrm{obs}}$-$M_{\mathrm{UV,obs}}$ relation previously obtained in the deeper narrow-area observations at $M_{\mathrm{UV}} = -18.9$ and $β= -1.94$, which coincides with the break point of $β_{\mathrm{obs}}$-$M_{\mathrm{UV,obs}}$ relation observed so far. The coincidence suggest that we see the almost dust-free population at $M_{\mathrm{UV,obs}} \gtrsim -18.9$.
description: 20 pages, 20 figures
Physico-chemical characterization of some selected soil series of Mymensingh and Jamalpur districts of Bangladesh
Creators: name: Sheel, P. R.
name: Chowdhury, M. A. H
name: Ali, M.
name: Mahamud, M. A
name: Sheel, P. R.
name: Chowdhury, M. A. H
name: Ali, M.
name: Mahamud, M. A
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: Soil Physico-chemical characterization
subject: Mymensingh
subject: Jamalpur

description: The soil physico-chemical properties have been disturbed due to long continued intensive agricultural practices. Under this situation we are approaching rapidly to a very strong future challenge in sustaining the quality of our soil. This study was conducted to evaluate the physico-chemical properties of the selected soil series. The area covered Mymensingh and Jamalpur districts of Bangladesh. Soil samples were collected randomly from different profiles of Lokdeo, Tarakanda, Silmondi and Melandah soil series during March-May, 2014 and analysed. All soils were acidic and textural classes were sandy loam, silt loam, loam, and clay loam. Organic matter and total N contents low to very low. Available S content in the upper layers of most soils were medium to optimum and in the deeper layer low to medium. The exchangeable K, Ca and Na contents were also low. The upper layers of all the locations contained higher amounts of available Zn. The available Cu and Fe contents of most soils were very high. The soils of all locations contained very high amount of available Mn except the deeper layers (45-75 cm) of Melandah which contained optimum amount of available Mn. Soil pH showed negative correlation with total N and available S. Total N showed positive correlation with soil OM, available Cu and available S. There was positive correlation between available S and available Mn.
Using Stream Features for Instant Document Filtering
Creators: name: Bauer, Andreas
name: Wolff, Christian
Publisher: name: Universität Regensburg
Year: 2012
Subjects: subject: information retrievalinformation filtering event processing web2.0 text streams real-time search tf/idf okapi stream features
subject: 004 Informatik
subject: H.2.4
subject: H.2.8
subject: H.3.3

description: In this paper, we discuss how event processing technologies can be employed for real-time text stream processing and information filtering in the context of the TREC 2012 microblog task. After introducing basic characteristics of stream and event processing, the technical architecture of our text stream analysis engine is presented. Employing well-known term weighting schemes from document-centric text retrieval for temporally dynamic text streams is discussed next, giving details of the ESPER Event Processing Agents (EPAs) we have implemented for this task. Finally, we describe our experimental setup, give details on the TREC microblog runs as well as the result thereafter with our system including some extensions and give a short interpretation of the evaluation results.
title: Queer History und historisches Lernen
title: Konzeptionen und Umsetzungen am Beispiel von queerhistory.de und des Archivs der anderen Erinnerungen
titleType: Subtitle
Creators: name: Lücke, Martin
Publisher: name: Universitätsverlag Kiel | Kiel University Publishing
Year: 2022
Subjects: subject: Geschlechterforschung
subject: Lehre
subject: Geschichte
subject: 370 Bildung und Erziehung
subject: Queer History
subject: Geschichtsunterricht
subject: historisches Lernen

description: Die Geschichte sexueller Vielfalt ist bisher kaum ein Thema des Geschichtsunterrichts. Unter Aufgreifen von Ansätzen aus der Queer Theory und den Queer Studies zeigt der Beitrag anhand des Projektes des Berliner Queer History Months und des Archivs der anderen Erinnerungen der Bundestiftung Magnus Hirschfeld konkrete Lernsettings auf, mit denen diese Geschichte auch in den Geschichtsunterricht integriert werden kann.
The Role of Shopping Mission in Retail Customer Segmentation
Creators: name: Sokol, Ondřej
name: Holý, Vladimír
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: In retailing, it is important to understand customer behavior and determine customer value. A useful tool to achieve such goals is the cluster analysis of transaction data. Typically, a customer segmentation is based on the recency, frequency and monetary value of shopping or the structure of purchased products. We take a different approach and base our segmentation on the shopping mission - a reason why a customer visits the shop. Shopping missions include focused purchases of specific product categories and general purchases of various sizes. In an application to a Czech drugstore chain, we show that the proposed segmentation brings unique information about customers and should be used alongside the traditional methods.
Mineral nutrient contents of some potato accessions of USA and Bangladesh
Creators: name: Mahamud, M. A
name: Chowdhury, M. A. H
name: Rahim, M.A.
name: Mohiuddin, K. M.
name: Mahamud, M. A
name: Chowdhury, M. A. H
name: Rahim, M.A.
name: Mohiuddin, K. M.
Publisher: name: Unknown
Year: 2015
Subjects: subject: Crop Production/Industries
subject: USA Potato accession
subject: Nutrient content

description: Twenty two potato accessions from USA were evaluated for nutrient contents. Two Bangladeshi varieties were also included for comparison. Nutritional analyses were performed in the Department of Agricultural Chemistry, BAU during November, 2014 to April, 2015. Considering macro nutrient content, the highest values of N, P, K and S were found in the accession AC 10062 whereas Ca and Mg contents were found highest in Bangladeshi variety Cardinal and USA accessions AC 10073, respectively. In case of micro nutrient, the maximum amounts of Cu, Mn, B and Zn were observed in accession AC 10110, AC 10069, AC 10073 and AC 10109, respectively. Significant positive correlations were observed between N-P, N-K and K-Mn contents while K-Mg, Mn-B and Cu-B contents were negatively correlated. Considering all the parameters studied, the USA accession AC 10062, AC 10069 and AC 10110 were nutritionally superior to Bangladeshi variety Diamant and Cardinal. The accession AC 10062 was found as the best USA accession to produce nutrient rich potato in Bangladesh.
Studies on Bone-mass Formation within a Theoretical Model
Creators: name: Hui, Nirmalendu
name: Chattopadhyay, Biplab
Publisher: name: arXiv
Year: 2019
Subjects: subject: Other Quantitative Biology (q-bio.OT)
subject: FOS: Biological sciences

description: Bone-mass formation in human is looked at to understand the underlying dynamics with an eye on healing of bone-fracture and non-unions in non-invasive pathways. Three biological cells osteoblasts, osteoclasts and osteocytes are important players in creating new bone or osseous matter in which quite a few hormones, proteins and minerals have indispensable supportive role. Assuming populations of the three mentioned cells as variables, we frame a theoretical model which is represented as a set of time differential equations. These equations imitate the dynamic process of bone matter creation. High value of osteocytes with moderate level values of osteoblast and osteoclast, all at asymptotic scale, imply creation of new bone-matter in our model. The model is studied both analytically and numerically. Some important results are highlighted and relevant predictions are made which could be put to future experimental test.
description: 14 pages, 11 figures, 1 table. arXiv admin note: substantial text overlap with arXiv:1307.5833