cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Discovery of novel isoflavone derivatives as AChE/BuChE dual-targeted inhibitors: synthesis, biological evaluation and molecular modelling
Creators: name: Feng, Bo
name: Li, Xinpeng
name: Xia, Jie
name: Wu, Song
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: AChE and BuChE are druggable targets for the discovery of anti-Alzheimer’s disease drugs, while dual-inhibition of these two targets seems to be more effective. In this study, we synthesised a series of novel isoflavone derivatives based on our hit compound G from in silico high-throughput screening and then tested their activities by in vitro AChE and BuChE bioassays. Most of the isoflavone derivatives displayed moderate inhibition against both AChE and BuChE. Among them, compound 16 was identified as a potent AChE/BuChE dual-targeted inhibitor (IC50: 4.60 μM for AChE; 5.92 μM for BuChE). Molecular modelling study indicated compound 16 may possess better pharmacokinetic properties, e.g. absorption, blood–brain barrier penetration and CYP2D6 binding. Taken together, our study has identified compound 16 as an excellent lead compound for the treatment of Alzheimer’s disease.
Non-Institutional Factors Affecting Microentrepreneurship Development in Bangladesh
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: subject: 150304 Entrepreneurship
subject: FOS: Economics and business

description: ABSTRACTThe magnitude of microentrepreneurial activities plays a decisive role in the economic development of the rural livelihoods, especially in third world countries. Microentrepreneurship has always been considered as a proven instrument to fight poverty in an effective manner. As a consequence, poverty alleviation through rural centric microentrepreneurship development has been focused formore than the last thirty five years in Bangladesh. However, despite such initiatives, the state of microentrepreneurship in Bangladesh has not yet reached to a satisfactory level. There are a number of prevailing factors that thwart thedevelopment of microentrepreneurship in Bangladesh. Among all the factors, non-institutions encompassing various political, economic, social, cultural, technological, environmental and personal factors are affecting the scopes of operating these economic activities to a significant extent. This paper attempts to identify the key non-institutional barriers that hinder the development ofmicroentrepreneurship in Bangladesh, and suggests a composite policy measure to overcome such encumbrances.
Distribution and diversity of twelve Curcuma species in China
Creators: name: Zhang, Lanyue
name: Wei, Jingwen
name: Yang, Zhiwen
name: Chen, Feng
name: Xian, Qiqiu
name: Su, Ping
name: Pan, Wanyi
name: Zhang, Kun
name: Zheng, Xi
name: Du, Zhiyun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Molecular Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Computational Biology

description: Genus Curcuma a wild species presents an important source of valuable characters for improving the cultivated Curcuma varieties. Based on the collected germplasms, herbariums, field surveys and other literatures, the ecogeographical diversity of Genus Curcuma and its potential distributions under the present and future climate are analysed by DIVA-GIS. The results indicate Genus Curcuma is distributed over 17 provinces in China, and particularly abundant in Guangxi and Guangdong provinces. The simulated current distributions are close to the actual distribution regions. In the future climate, the suitable areas for four Curcuma species will be extended, while for other three species the regions will be significantly decreased, and thus these valuable resources need protecting.
New brefeldins and penialidins from marine fungus Penicillium janthinellum DT-F29
Creators: name: Cheng, Xiangwei
name: Yu, Liyan
name: Wang, Qianqian
name: Ding, Wanjing
name: Chen, Zhe
name: Ma, Zhongjun
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Inorganic Chemistry
subject: FOS: Chemical sciences

description: A fermentation of marine fungus Penicillium janthinellum DT-F29 on solid rice medium led to the isolation of three new compounds, brefeldin D (1) and penialidins D-E (5–6), along with other five known brefeldins and penialidins. The structures of above compounds were determined on the basis of MS and NMR analysis.
title: 01_1771
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
Pollen morphology of Polygonatae and its systematic significance
Creators: name: Wang, Liu
name: Gu, Lei
name: Zhao, Chunhai
name: Liu, Jiaxi
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Environmental Sciences not elsewhere classified
subject: Ecology
subject: Developmental Biology

description: The pollen morphology of 54 species and one variety of seven genera in Polygonatae including Clintonia, Disporopsis, Disporum, Maianthemum, Polygonatum, Smilacina and Streptopus was observed and studied in detail; of these, nine species were reported for the first time. Our results showed that the surface ornamentation of pollen grains of the studied materials could be divided into seven types, namely gemmate, granulate-foveolate, perforate, reticulate, rugulate, rugulate-perforate and verrucate. In line with previous studies, we believe that (i) Smilacina ginfushanicum should be classified into the genus Heteropolygonatum rather than the genus Smilacina; (ii) Polygonatum should be divided into section Polygonatum and section Verticillata; (iii) Smilacina and Maianthemum should be combined as one genus, i.e. Maianthemum sensu lato; and (iv) Clintonia, Disporum and Streptopus should be separated from the tribe Polygonatae.
L'etat du marché de travail et l'intention de départ des jeunes cadres des banques commerciales au Togo : une approche par la théorie du signal
Creators: name: AHOLO, Atsu
name: HOUNKOU, Emmanuel Cosi
Publisher: name: Zenodo
Year: 2024
Subjects: Intention de départ ; signaux d'opportunités ; variables environnementales ; les jeunes cadres ; la conservation des expériences acquises.

description: Cette recherche vise à faire ressortir les variables environnementales qui influencent l’intention de départ des jeunes cadres des banques commerciales au Togo. L’analyse thématique manuelle et automatisée sous le logiciel IRAMUTEQ (version 07 alpha 2) explique les aspirations des jeunes cadres du secteur bancaire au Togo quant à leur intention de départ. Il ressort de l’analyse qualitative des données recueillies auprès de dix (10) institutions bancaires un intérêt accordé aux signaux d’opportunités alléchantes sur le marché du travail. Dans un souci d’évolution de leur carrière et d’amélioration de leurs conditions économiques, ces jeunes cadres sont prédisposés à saisir les différentes opportunités permettant la réalisation de leurs ambitions. La disponibilité des signaux d’opportunités répondant aux attentes de ce personnel et l’amélioration des conditions économiques sur le marché, se présentent en conséquence comme des raisons justifiant leur infidélité. Il est à noter aussi que la conservation des expériences acquises d’une banque à l’autre est un facteur qui encourage l’infidélité dans ledit secteur.
Identification of spinach SIAMESE and analysis of its function in plant immunity
Creators: name: Wang, Tianhua
name: Song, Teng
name: Xu, Chenxi
name: Cai, Xiaofeng
name: Wang, Xiaoli
name: Ma, Huimin
name: Zhou, Jianjian
name: Ge, Chenhui
name: Wang, Quanhua
name: Wang, Shui
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Medicine
subject: Cell Biology
subject: Immunology
subject: FOS: Clinical medicine
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: FOS: Biological sciences
subject: Computational Biology

description: Diseases cause a significant loss in both yield and quality of spinach. The cell cycle signalling pathway plays a central role in balancing development and immunity of plants. Cyclin-Dependent Kinase Inhibitor (CKI) is a core cell cycle regulator. It has been found that two Arabidopsis CKIs, SIAMESE (SIM) and SMR1 (SIAMESE-Related 1), function redundantly not only as negative regulators of cell proliferation but also as positive regulators of plant immunity. In the spinach genome, we identified a homologue of Arabidopsis SIM, referred to as Spinacia oleracea SIAMESE (SoSIM). To investigate the function of SoSIM, we introduced the 35S promoter-driven SoSIM (35S:SoSIM) into Arabidopsis sim smr1 double mutants. Over-expression of SoSIM phenocopied RNA interference of Cyclin-Dependent Kinase A1 (CDKA1) which exhibited dwarf and serrated leaves, confirming that SIM is a CDK inhibitor. Arabidopsis wild-type trichomes are single and unicellular, whereas sim smr1 mutant trichomes are clustered and multicellular. SoSIM restored wild-type trichome phenotype of sim smr1 mutant. The sim smr1 mutants were susceptible to the avirulent pathogen Pseudomonas syringae pv. maculicola as compared with wild-type plants. Our data showed that the resistance of 35S:SoSIM-transgenic sim smr1 lines to the pathogen was fully restored, indicating that SoSIM activates plant immunity. These data verify that SoSIM functions as its Arabidopsis counterpart in inhibition of plant development and activation of plant immunity. Therefore, SoSIM can be explored to control the balance between development and immunity in spinach.
COVID-19 Science Report: Therapeutics
Creators: name: Jason Chin-Huat Yap,
name: Ian Yi Han Ang,
name: Sharon Hui Xuan Tan,
name: Jacinta I-Pei Chen,
name: Ruth Frances Lewis,
name: Qian Yang,
name: Rowena Kah Sin Yap,
name: Bob Xian Yi Ng,
name: Hao Yi Tan,
Publisher: name: National University of Singapore
Year: 2020
Subjects: COVID-19
SARS-CoV-2
2019-nCoV
COVID19
coronavirus
therapeutics
drug therapy
medication
interferons
Lopinavir
Ritonavir
Kaeltra
umifenovir
arbidol
Remdesivir
Chloroquine
Ribavirin
Corticosteroids
Convalescent Plasma

description: There is currently no specific drug treatment for COVID-19. Existing drugs used to treat other conditions may be candidates and repurposed for COVID-19, these are undergoing clinical trials in China. The COVID-19 Science Report: Therapeutics summarises the research in relation to potential drug treatments.
Effects of tensor spin polarization on the chiral restoration and deconfinement phase transitions
Creators: name: Bao, Yan-Ru
name: Feng, Sheng-Qin
Publisher: name: arXiv
Year: 2024
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: Effects of tensor spin polarization (TSP) on the chiral restoration and deconfinement phase transitions are studied in Polyakov loop extended Nambu-Jona-Lasinio (PNJL) model. For chiral phase transition, the higher the polarized degree of quark-antiquark pairs under the strong magnetic field, the higher the phase transition temperature. The TSP corrects the position of the critical end point. The small impact of TSP on the phase transition temperature is found for the deconfinement phase transition. On the other hand, we divide the phase space into three ranges based on the phase diagram obtained from the PNJL model: the confinement phase with chiral symmetry broken, the deconfinement phase with restored chiral symmetry, and the confinement phase with restored chiral symmetry (quarkyonic phase). It is found that TSP has only a very small effect on the anisotropic pressure in the deconfined phase with chiral symmetry restored and the quarkyonic phase, but it has a very strong effect on the anisotropic pressure in the confined phase with chiral symmetry broken. This is because TSP is closely related to chiral symmetry. The restoration of chiral symmetry means the dissociation of spin polarization condensate.
description: 20 pages, 7 figures
title: COVID-19 Science Report: Vaccines
Creators: name: Yap, Jason Chin-Huat
name: Ang, Ian Yi Han
name: Tan, Sharon Hui Xuan
name: Chen, Jacinta I-Pei
name: Lewis, Ruth Frances
name: Yang, Qian
name: Yap, Rowena Kah Sin
name: Ng, Bob Xian Yi
name: Tan, Hao Yi
Publisher: name: National University of Singapore
Year: 2020
Subjects: COVID-19
SARS-CoV-2
2019-nCoV
novel coronavirus
vaccination

description: The COVID-19 Science Report: Vaccines is a current update on the development of vaccines for COVID-19. This includes the types of vaccines under development, the companies and institutions involved, the stages of vaccine development, and expected timelines. The report also includes a description of vaccines for related viruses such as SARS and MERS.
COVID-19 Science Report: Containment Measures
Creators: name: Jason Chin-Huat Yap,
name: Ian Yi Han Ang,
name: Sharon Hui Xuan Tan,
name: Jacinta I-Pei Chen,
name: Ruth Frances Lewis,
name: Qian Yang,
name: Rowena Kah Sin Yap,
name: Bob Xian Yi Ng,
name: Hao Yi Tan,
Publisher: name: National University of Singapore
Year: 2020
Subjects: containment measures
control measures
pandemic
epidemic
outbreak
SARS
MERS
H1N1
COVID-19
SARS-CoV-2
2019-nCoV
coronavirus
respiratory illnesses
border control
travel restrictions
spread
border quarantine
isolation
quarantine
detection
release after quarantine/isolation
hospital
healthcare
protection of healthcare personnel
protection of healthcare worker
infection control
community hygiene
hand hygiene
use of mask
face mask
N95 mask
surgical mask
risk communication
social distancing
workplace closure
school closure
business continuity plan
BCP
working arrangements
HR working arrangements
workplace
effectiveness
cost impact
implications

description: The COVID-19 Science Report: Containment Measures surveys the current literature on non-pharmaceutical measures historically and typically used in a pandemic outbreak of respiratory diseases, and summarises the key measures taken, evidence on their effectiveness and efficiency, and considerations and impact from their deployment.
Plumbago auriculata leaf extract-mediated AgNPs and its activities as antioxidant, anti-TB and dye degrading agents
Creators: name: Jaryal, Neeraj
name: Kaur, Harpreet
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Infectious Diseases
subject: FOS: Health sciences

description: In the present work, silver nanoparticles have been biosynthesized by utilizing the alcoholic extract of Plumbago auriculata. The optimization of reaction conditions was carried out by monitoring the reactions with the help of UV–Visible absorption spectroscopy. The characterization of AgNP was carried out by infrared spectroscopy, transmission electron microscopy and X-Ray diffraction (XRD) studies. The biogenic AgNPs were tested against Mycobacterium tuberculosis using Microplate Almar Blue assay (MABA) and their antioxidant activity was also evaluated. The silver nanoparticles were also assessed for their reducing activity against organic dyes. The AgNPs were spherical in shape with size ranging from 15 to 45 nm with face centered cubic geometry as revealed by XRD analysis. The AgNPs possessed good antitubercular activity with MIC value of 1.6 μg/ml and these also exhibited promising antioxidant activity with IC50 value of 28.2. Furthermore, AgNPs also reduced congo red within 2 h and malachite green was degraded within 40 min. The present work demonstrated the utilization of P. auriculata for biosynthesis of AgNP which could be a potential candidate for antitubercular drug development and it could also be used as an antioxidant agent. The application of AgNP in reducing agent can be further extended and evaluated for purification of effluent water from textile industries.
THE RELATIONSHIPS BETWEEN THE SOCIOECONOMIC PROFILE OF FARMERS AND PADDY PRODUCTIVITY IN NORTH-WEST SELANGOR, MALAYSIA
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: Economics

description: Paddy is the main food crop in Malaysia, but due to a low rate of productivity, the land areafor paddy production is gradually decreasing. As a consequence, it is critically important toknow the socio-economic characteristics of the paddy farmers and their linkage withagricultural productivity to ensure the sustainability of paddy farms as well as farmers’livelihood. This study analyses the relationships between the paddy yields and the socioeconomiccharacteristics of the farmers in the Integrated Agricultural Development Area(IADA), North-West Selangor, Malaysia. The data was collected through a survey. Toanalyse the data, this study conducted cross-sectional multiple OLS regressions. The findingsof the study revealed that several socio-economic and physical characteristics had significanteffects on paddy productivity in Malaysia. Based on the findings, some policyrecommendations and action plans have been proposed focusing on paddy productivity andsocio-economic sustainability of the livelihood. The findings of the study are important forthe policymakers and relevant agencies.
Phantom scalar field cosmologies constrained by early cosmic measurements
Creators: name: Nájera, José Antonio
name: Escamilla-Rivera, Celia
Publisher: name: arXiv
Year: 2024
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: FOS: Physical sciences

description: In this work, we explore new constraints on phantom scalar field cosmologies with a scalar field employing early times catalogues related to CMB measurements, along with the local standard observables, like Supernovae Type Ia (SNIa), $H(z)$ measurements (Cosmic Clocks), and Baryon Acoustic Oscillations (BAO) baselines. In particular, we studied a tracker phantom field with hyperbolic polar coordinates that have been proposed in the literature. The main goal is to obtain precise cosmological constraints for $H_0$ and $σ_8$, in comparison to other constructions that present tension in early cosmological parameters. Our results show that phantom scalar field cosmologies have a reduced statistical tension on $H_0$ that it is less than 3$σ$ using model-independent CMB catalogues as SPT-3G+WMAP9 and ACTPol DR-4+WMAP9 baselines. This suggests these models using a different phantom potential might address the Hubble constant problem and reduce the systematics involved.
description: 10 pages, 3 figures
Palaeozoic evolution of the North Tianshan based on palaeomagnetic data – transition from Gondwana towards Pangaea
Creators: name: U. Kirscher
name: V. Bachtadse
name: A. V. Mikolaichuk
name: A. Kröner
name: D. V. Alexeiev
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Neuroscience
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 111714 Mental Health
subject: FOS: Health sciences

description: We present new palaeomagnetic data for Cambrian and Ordovician volcanic and sedimentary rocks from the Kyrgyz North Tianshan (NTS) and review available data from the southwestern Central Asian Orogenic Belt (CAOB) to elucidate the tectonic history and evolution of this region during the early Palaeozoic. We observed a coherent evolution of the NTS and the Kazakhstan continent (or Kazakhstania) with a constant northwards movement between the Cambrian and Devonian at ∼5 cm/a. After the northwards movement ceased in the Devonian, the accreted terrane assemblage of Kazakhstania occupied a stable latitudinal position at ∼30°N until the final amalgamation of Eurasia occurred in the late Carboniferous to early Permian. Amalgamation of the Tarim and Turan blocks caused a counterclockwise bending within the southwestern segment of the CAOB, which occurred in an inconsistent way by a brittle-like response of the upper crust with a large variety of rotational movement. We suggest an evolution of the Kyrgyz CAOB terranes by steady migration away from Gondwana and subsequent capture in a zone of global downwelling at ~30°N, where accretion and subsequent amalgamation of Eurasia occurred with the CAOB terranes in its centre.
Considerable Issues for Sustainable Public-Private Partnership (PPP) Project
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: subject: 150304 Entrepreneurship
subject: FOS: Economics and business

description: AbstractThe implications of Public Private Partnership (PPP) concept has acknowledged utmostattention from different governments around the world especially in terms of service quality,efficiencies in procurement and risk management, extent of investment undertaken by privatesponsor and the ability to generate managerial and technical capabilities. PPPs are seen as away forward for creating a sustainable atmosphere in terms of economic, social andenvironmental considerations. However, the variations of PPP schemes have their own set ofadvantage and limitations over one to another vis-a-vis typical public sector procurement.While adopting and promoting PPPs in a country by the government and involving privatesector for a particular PPP deal, specific issues and factors associated with the project must beconsidered for ensuring sustainibility of the project as well as the interst of all stakeholders,i.e, government, private sector and the users. This study focuses on these factors that willhelp the involved parties to ensure the sustainability of the PPP projects and a fruitful winwincontract.
The Processes of Location Study for Developing Economic Zones under Public Private Partnership Model: Country Study on Bangladesh
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: Economics

description: AbstractIn spite of the complexity in defining the boundary, the concept of Economic Zones (EZ)has been evolved as a way forward for the government of the developing countries forenhancing the national trade. Similarly the recent phenomenon of widespread PublicPrivate Partnership (PPP) practices especially in infrastructure sector is also providing awindow to develop many of such economic zones through PPP model as EZ typically iscapital intensive. Bangladesh has discrete success both under PPP and EZ regime.However, developing EZ under PPP model has few commercial complexities as both thepublic and private sector need to bear some roles and obligations one of which is selectionof appropriate location for EZ development. The location study for PPP EZ developmenttherefore receives paramount attention both from developer and lenders perspective. Suchlocation study generally is not typical project site study by nature, rather it is moreeconomic concentrated. This paper will try to identify the factors that are essential toconsider for conducting these location studies based on the examples of Bangladesh. Thepaper will also identify the appropriate methods and approaches required for successfulEZ development through PPP.
A False Sense of Privacy: Towards a Reliable Evaluation Methodology for the Anonymization of Biometric Data
Creators: name: Hanisch, Simon
name: Todt, Julian
name: Patino, Jose
name: Evans, Nicholas
name: Strufe, Thorsten
Publisher: name: arXiv
Year: 2023
Subjects: subject: Cryptography and Security (cs.CR)
subject: FOS: Computer and information sciences

description: Biometric data contains distinctive human traits such as facial features or gait patterns. The use of biometric data permits an individuation so exact that the data is utilized effectively in identification and authentication systems. But for this same reason, privacy protections become indispensably necessary. Privacy protection is extensively afforded by the technique of anonymization. Anonymization techniques protect sensitive personal data from biometrics by obfuscating or removing information that allows linking records to the generating individuals, to achieve high levels of anonymity. However, our understanding and possibility to develop effective anonymization relies, in equal parts, on the effectiveness of the methods employed to evaluate anonymization performance. In this paper, we assess the state-of-the-art methods used to evaluate the performance of anonymization techniques for facial images and for gait patterns. We demonstrate that the state-of-the-art evaluation methods have serious and frequent shortcomings. In particular, we find that the underlying assumptions of the state-of-the-art are quite unwarranted. State-of-the-art methods generally assume a difficult recognition scenario and thus a weak adversary. However, that assumption causes state-of-the-art evaluations to grossly overestimate the performance of the anonymization. Therefore, we propose a strong adversary which is aware of the anonymization in place. We improve the selection process for the evaluation dataset, and we reduce the numbers of identities contained in the dataset while ensuring that these identities remain easily distinguishable from one another. Our novel evaluation methodology surpasses the state-of-the-art because we measure worst-case performance and so deliver a highly reliable evaluation of biometric anonymization techniques.
In vitro drug–drug interactions of budesonide: inhibition and induction of transporters and cytochrome P450 enzymes
Creators: name: Chen, Nancy
name: Cui, Donghui
name: Wang, Qing
name: Wen, Zhiming
name: Finkelman, Richard D.
name: Welty, Devin
Publisher: name: Taylor & Francis
Year: 2017
Subjects: subject: Biochemistry
subject: Medicine
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Mental Health
subject: Hematology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Virology

description: 1. Budesonide is a glucocorticoid used in the treatment of several respiratory and gastrointestinal inflammatory diseases. Glucocorticoids have been demonstrated to induce cytochrome P450 (CYP) 3A and the efflux transporter P-glycoprotein (P-gp). This study aimed to evaluate the potential of budesonide to act as a perpetrator or a victim of transporter- or CYP-mediated drug–drug interactions (DDIs). 2. In vitro studies were conducted for P-gp, breast cancer resistance protein and organic anion and cation transporters (OATP1B1, OATP1B3, OAT1, OAT3, OCT2) in transporter-transfected cells. Changes in mRNA expression in human hepatocytes and enzyme activity in human liver microsomes by budesonide were determined for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP3A. 3. The data indicated that budesonide is a substrate of P-gp but is not a substrate or an inhibitor of the other transporters investigated. Budesonide is neither an inducer nor an inhibitor of major CYP enzymes. The effect of P-gp on budesonide disposition is anticipated to be low owing to CYP3A-mediated clearance. 4. Collectively, our data indicate there is a low risk of budesonide perpetrating clinical DDIs mediated by the transporters or CYPs studied.
Thermal Stress Analysis of a Continuous Rigid Frame Bridge
Creators: name: Ge, Shiwei
name: Xu, Yafei
name: Zhou, Xiao
name: Peng, Shangyu
Publisher: name: figshare
Year: 2017
Subjects: classificationCode: 339999
subject: Other built environment and design not elsewhere classified

description: Thermal stress of a continuous rigid frame bridge, based on the
temperature gradient in Chinese bridge gauge, using a finite element
analysis (FEA) method was investigated. First of all, the temperature
effect of the whole bridge was analyzed, and the correlation of the
improved amplitude of temperature gradient and temperature effect were
studied. It was found that there was a linear relationship with
temperature stress and improved temperature. And then, the temperature
effect of zero block was analyzed and the details of box girder
temperature stress distribution investigated by utilizing the FEA
method. It was concluded that temperature stress mainly distributed in
the body surface; under the condition of the improvement of temperature
field, the center temperature stress of zero block was improved about
60% and the end temperature stress of zero block was improved about 75%.
Policy Brief on the CFP external dimension towards 2022
Creators: name: Chapela, Rosa
name: Vidal, Duarte F.
name: Rodriguez, Alexandre
name: Doblado, Sonia
name: Galvao, Juliana
name: Mikkelsen, Nina
name: Fonseca, Benvindo
name: Diallo, Mamadou
name: Bouzouma, Moustapha
name: Lucas, Vincent
name: Thiam, Ndiaga
name: Ngom, Fambaye
name: Roucou, Yannick
name: Davidson, Mary Frances
Publisher: name: Zenodo
Year: 2021
Subjects: SFPA - Sustainable Fisheries Partnership Agreements
CFP - Common Fisheries Policy
Fisheries management

description: The External Dimension of the Common Fisheries Policy (CFP) has increased its visibility in the last decades, both in relation to its coherence with the internal dimension (comprising bilateral access agreements within EEZ and the management of international waters subject to jurisdiction of Regional Fisheries Management Organizations) and its links with other EU policies such as cooperation for development, human rights, labour, health and trade issues.
 As a relevant player in the development of global fisheries governance, the EU has an enhanced responsibility to promote sustainable and responsible fisheries management into the international scene, in its double role as a major fishing actor and the largest single market for marine products in the world.
 The External fisheries policy ensures the EU commitment to jointly manage fish stocks outside EU waters where the EU fleet operates. It is in practice implemented by an active participation of the EU and other countries States and partners from around the globe through the United Nations system, including the Food and Agriculture Organisation the International Maritime Organisation or United Nations Conference on Trade and Development, Regional Fisheries Management Organizations and Regional Sea Conventions, as well as other international and regional bodies.
 However, despite the solid theoretical foundations, internationally agreed principles and overarching goals upon which the External Dimension of the CFP is built, there are still many weaknesses and challenges that are hampering an effective implementation
 This policy report summarizes the core elements of the EU’s external fisheries policy, providing recommendations aimed to inform the revision process of the CFP towards 2022, while contributing to the achievement of the Sustainable Development Goals under Agenda 2030.
Impacts of Climate Change on Agriculture and Food Security Issues in Malaysia: An Empirical Study on Farm Level Assessment
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: subject: 40104 Climate Change Processes
subject: FOS: Earth and related environmental sciences

description: ABSTRACTClimate change is proven to have had impacted the agricultural productivity, crop choice, andfood security everywhere in the world. The nature, scale, frequency, and outcome of suchimpact differ significantly among countries, regions and areas within a country. This study isan effort to empirically investigate theses issues for Malaysia using both primary andsecondary data collected from and relevant to the Integrated Agriculture Development Areasin the Northwest Selangor. The results reveal that climate change phenomenon such asnatural disaster, drought, flood, pest attack, plant disease, and changing the time of crop cyclehave adversely been impacting Malaysian agriculture and its productivity as well asprofitability. Despite continuous increases of government subsidy as well as permission onlyfor paddy production, the paddy planting area is decreasing as the agricultural farmers oftenexperience adverse impacts of climatic variation. So, climate change phenomenon is alsodepressingly impacting the state of food security among the farmers. As climate change isuniversal and its existence is indefinite, the farmers need to adapt to and find ways to mitigatethe damages of climatic variation in order for them to sustain agricultural productivity andattain food security
Impacts of Climate Change on Agriculture and Food Security Issues in Malaysia: An Empirical Study on Farm Level Assessment
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: subject: 40104 Climate Change Processes
subject: FOS: Earth and related environmental sciences

description: ABSTRACTClimate change is proven to have had impacted the agricultural productivity, crop choice, andfood security everywhere in the world. The nature, scale, frequency, and outcome of suchimpact differ significantly among countries, regions and areas within a country. This study isan effort to empirically investigate theses issues for Malaysia using both primary andsecondary data collected from and relevant to the Integrated Agriculture Development Areasin the Northwest Selangor. The results reveal that climate change phenomenon such asnatural disaster, drought, flood, pest attack, plant disease, and changing the time of crop cyclehave adversely been impacting Malaysian agriculture and its productivity as well asprofitability. Despite continuous increases of government subsidy as well as permission onlyfor paddy production, the paddy planting area is decreasing as the agricultural farmers oftenexperience adverse impacts of climatic variation. So, climate change phenomenon is alsodepressingly impacting the state of food security among the farmers. As climate change isuniversal and its existence is indefinite, the farmers need to adapt to and find ways to mitigatethe damages of climatic variation in order for them to sustain agricultural productivity andattain food security.
Projective Methods for Mitigating Gender Bias in Pre-trained Language Models
Creators: name: Dawkins, Hillary
name: Nejadgholi, Isar
name: Gillis, Daniel
name: McCuaig, Judi
Publisher: name: arXiv
Year: 2024
Subjects: subject: Computation and Language (cs.CL)
subject: FOS: Computer and information sciences

description: Mitigation of gender bias in NLP has a long history tied to debiasing static word embeddings. More recently, attention has shifted to debiasing pre-trained language models. We study to what extent the simplest projective debiasing methods, developed for word embeddings, can help when applied to BERT's internal representations. Projective methods are fast to implement, use a small number of saved parameters, and make no updates to the existing model parameters. We evaluate the efficacy of the methods in reducing both intrinsic bias, as measured by BERT's next sentence prediction task, and in mitigating observed bias in a downstream setting when fine-tuned. To this end, we also provide a critical analysis of a popular gender-bias assessment test for quantifying intrinsic bias, resulting in an enhanced test set and new bias measures. We find that projective methods can be effective at both intrinsic bias and downstream bias mitigation, but that the two outcomes are not necessarily correlated. This finding serves as a warning that intrinsic bias test sets, based either on language modeling tasks or next sentence prediction, should not be the only benchmark in developing a debiased language model.
Data Table for Tick Island Zooarchaeological Specimens [Structured Data from Open Context]
Creators: name: Kitty F Emery
name: Otto Jahn
name: Ripley P Bullen
name: Elizabeth Wing
name: Laura Brenskelle
name: Michelle LeFebvre
name: Kitty F Emery
name: Rob Guralnick
name: Michelle LeFebvre
name: Laura Brenskelle
name: John W Wieczorek
Publisher: name: Zenodo
Year: 2023
Subjects: Open Context
Data Publication
Structured Data
GeoJSON
JSON-LD
CSV

description: This deposit archives structured-data files associated with the Data Table for Tick Island Zooarchaeological Specimens Data Table resource published by Open Context.
In general, Open Context is a dynamic and frequently updated database that integrates research data from a growing number of sources. However, Open Context also stores some static and unchanging, externally stored "Data Table" files. Unless otherwise indicated, the content of Data Table files (such as the resource deposited here) will not change even after updates to the Open Context database.
Deposition File Overview
This archival deposit includes two files, in two formats:

CSV: The 137-data-table-for-tick-island-zooarchaeological-specimens.csv contains the tabular data content for this resource in a CSV format.
JSON: The 137-data-table-for-tick-island-zooarchaeological-specimens.json provides additional metadata about the tabular data content for this resource in a JSON-LD format.
Open Context is an open-source Python application built with the Django framework (see source code and Docker deployment code). To manage a wide variety of archaeological and related data, Open Context organizes information using a very abstract, graph-based schema. Open Context implements this schema using a Postgres relational database and the Django "Object Relational Model" (ORM).
Because Open Context internally maintains data using a very abstract schema, data dumps directly from this schema would be difficult to understand and use. Therefore, Open Context makes select datasets (like this) available in more easily understood tabular expressions. A considerable amount of application logic in Open Context generated the more expressive tabular representation of data. This tabular data output from Open Context is meant to be considered as a static and unchanging "snapshot" of data selected for output at a specific time.
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Open Context publishes research materials important to many different communities all with different histories, cultures, and expectations. We expect uses of these data to respect civil, legal, and ethical standards. To learn more about these expectations, please review:

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Neutrophil to Lymphocyte Ratio (NLR) in Peripheral Blood: A Novel and Simple Prognostic Predictor of Non-small Cell Lung Cancer (NSCLC)
Creators: name: Luo, Yu Siyuan and Peng
name: Xu, Xinjie
name: Fan, Liyu
name: Zou, Ziyuan
name: Zhang, Xiaoli
Publisher: name: figshare
Year: 2017
Subjects: classificationCode: 320102
subject: Haematology

description: Lung cancer is the leading cause of cancer-related deaths worldwide, and
 almost accounts for 20% of these deaths, however, the cure rate is less
 than 10% [1]. Non-small cell lung cancer (NSCLC) accounts for
approximately 85% of all cases of lung cancer [1], but fewer than 15% of
 individuals diagnosed with NSCLC can survive for more than 5 years,
which poses a great threat to the patient’s life and health [2].
Recently, the incidence of lung cancer keeps dynamically growing, but
more than 75% of patients at diagnosis has appeared local development or
 metastasis, missing the best period of surgery. Moreover, despite
surgical treatment is the optimal choice for early-stage NSCLC patients,
 30%-40% of patients with NSCLC develop tumor recurrence in a short
time. Therefore, improving the prognosis of patients with lung cancer
and predicting the long-term survival of patients is of particular
importance [3]. At present, tumor and node metastasis (TNM) staging
system, clinicopathological characteristics, visceral pleural invasion
and marginal status are used to predict the disease progression and
overall survival of NSCLC patients. There is no index which is stable,
effective, reliable and less harmful to assess prognosis, predict
recurrence risk and overall survival.
An Empirical Evidence of International Fisher Effect in Bangladesh with India and China: A Time-Series Approach
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: subject: 50205 Environmental Management
subject: FOS: Earth and related environmental sciences

description: AbstractThis paper is an attempt to examine the empirical evidence of International Fisher Effect(IFE) between Bangladesh and its two other major trading partners, China and India. TheIFE uses interest rate differentials to explain why exchange rates change over time. A timeseries approach is considered to trace the relationship between nominal interest rates andexchange rates in these countries. The estimated value, by applying OLS, is used todetermine the casual relationship between interest rates and exchange rates for quarterlydata from 4th Quarter, 1995 to the 2nd Quarter, 2008. The empirical results suggest that thereis a little correlation between exchange rates and interest rates differential for Bangladeshwith China and Bangladesh with India, and the relationship between the variables is alsonot noteworthy for Bangladesh. Further, the trends advocate that the forecasting ofexchange rates with the hypothesis of IFE is not realistic for these countries.
The Relationships between Exchange Rates and Stock Prices: Empirical Investigation from Johannesburg Stock Exchange
Creators: name: Alam, Mahmudul
Publisher: name: figshare
Year: 2017
Subjects: subject: 150299 Banking, Finance and Investment not elsewhere classified
subject: FOS: Economics and business

description: ABSTRACTThis study seeks evidence supporting the existence of market efficiency and exchange ratesensitivity on stock prices in the Johannesburg stock exchange (JSE). The sample includesthe daily price indices of all securities listed on the JSE, and the exchange rate of theUSD/Rand for the period since January 2000 to December 2004. The results from the unitroot test, the ADF test and the causality test at the Granger sense provide evidence that theJohannesburg stock exchange (JSE) is informationally efficient. It has a long run comovementwith exchange rate, and long run equilibrium or steady state. Hence, in JSE thereis a strong possibility that foreign direct investors and forex market traders cannot influenceand gain abnormal extra benefits by using exchange rate mechanism or by using exchangerate to forecast stock prices in the market. So, JSE is semi-strong form efficient. Through cointegrationtest, this paper gives more insight on the concept of market efficiency and thereliability of the results. These results are important to security analysts, investors, andsecurity regulatory exchange bodies in policy making decision to improve the marketconditions.
title: Trench etched polarisation pinned multimode vertical cavity surface emitting lasers
Creators: name: Lei, Danqi
Publisher: name: University of Glasgow
Year: 2022

description: In this thesis, stable polarisation VCSELs for SPIC systems are fabricated, characterised and analysed. The application requires VCSELs to satisfy the polarisation preference of a buttcoupling coupler in the structure and be embedded into the planar SPICs system to provide light for an EDWA. The design of the VCSELs considered device polarisation characteristics and device structure. Discussions about it is presented in the thesis. VCSELs with 30μm wide and 9μm deep trenches etched next to it are fabricated by a repeatable fabrication process. Deep trenches with sharp edges were accomplished by dry etching techniques presented in this fabrication flow. Devices with diameter of 40μm, 30μm, 20μm and 10μm are achieved by this fabrication process that has a potential of large-scale production. Device characteristics including output power, contact resistance, slope efficiency, wall-plug efficiency, emission spectra, polarisation direction, polarisation ratio and nearfield images are examined. The properties of different diameter devices are discussed. 40μm diameter device achieves the highest output power of 4.6mW with a power loss of 76% in the substrate. It was found that 40μm and 30μm diameter devices produced stable polarisation selection, however, 20μm and 10μm diameter devices show unstable polarisation characteristics. An investigation of polarisation properties of the fabricated trench-etched VCSELs is carried out using polarised near-field and spectral measurements. The nearfield images took at subthreshold have been compared between orthogonal polarisation states for different diameter devices. A spontaneous emission intensity difference is found for 40μm and 30μm diameter devices. It is possible that gain distribution is different on orthogonal polarisation states. A further birefringence study is presented for 40μm trench-etched VCSELs at around threshold and above threshold. Around threshold, spatially overlapping lasing modes allow the birefringence and hence strain to be mapped, indicating higher strain in the centre of the device. For high currents, it is observed that the lasing of different polarisations occurs in different regions of the device, as opposed to being a temporal phenomenon.
Synthesis process of AOPA from Flame-retardant polyvinyl alcohol membrane with high transparency based on a reactive phosphorus-containing compound
Creators: name: Peng, Sha
name: Zhou, Ming
name: liu, Feiyan
name: Zhang, Chang
name: Liu, Xueqing
name: Liu, Jiyan
name: Zou, Liyong
name: Chen, Jia
Publisher: name: The Royal Society
Year: 2017

description: Scheme for synthesis of AOPA