Additional file 1 of Neuroprotective effects of strength training in a neuroinflammatory animal model
Creators: name: de Gregório, Elizama
name: Mendes, Gabriela Cristiane
name: Somensi, Lincon Bordignon
name: Freire, Cassio Geremia
name: Lopes, Luiza Freitas
name: Lima, Karine Ramires
name: Carrazoni, Guilherme Salgado
name: Neves, Ben-Hur Souto
name: Picua, Steffanie Severo
name: da Silva, Luisa Mota
name: Mello-Carpes, Pamela Billig
name: Bonini, Juliana Sartori
name: da Silva, Weber Claudio
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Neuroscience
subject: Physiology
subject: FOS: Biological sciences
subject: Immunology
subject: FOS: Clinical medicine
subject: 69999 Biological Sciences not elsewhere classified
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Additional file 1: Table S1. Eight weeks of strength exercise previously to the infusion of intra-CA1 dorsal bilateral infusion of LPS (40 µg/side) induced an increase in the grip strength. Table S2. Eight weeks of strength exercise previous to the intra-CA1 dorsal bilateral infusion of LPS (40 µg/side) improves the performance of rats in the retention of the short-term (STM) or recent long-term discriminative memory (LTM) relative to the object recognition task. Table S3. Eight weeks of strength exercise. previously to the intra-CA1 dorsal bilateral infusion of LPS (40 µg/side). improves the performance of rats in the retention of recent long-term social memory (LTM) regarding the task of social recognition. Table S4. Eight weeks of strength exercise previously to the intra-CA1 dorsal bilateral infusion of (40 µg/side) induces physiological cardiac hypertrophy caused by muscular training. Table S5. Eight weeks of strength exercise hindered the enhancement of rats' dark neuron count verified after intra-CA1 dorsal bilateral infusion of LPS (40 µg/side) in the hippocampus CA1 region. Table S6. Expression of GSH and activity of the enzymes MPO. SOD. CAT and GST in the CA1 region of hippocampus of rats. (A) Eight weeks of strength exercise diminished the hippocampus concentration of GSH in the rats' hippocampus previously submitted to the strength exercise compared to the non-exercised rats. (D) increased the activity of CAT in the hippocampus of rats that received local induction of neuroinflammation. and (B. C and E) does not affect the activity of MPO. SOD and GST in the hippocampus. respectively. Table S7. Expression of GSH and from the enzymes MPO. SOD. CAT and GST in the prefrontal cortex of rats. Eight weeks of strength exercise diminished the activity of CAT in the prefrontal cortex of rats. compared to non-exercised rats. except when the rats were submitted to intra-CA1 dorsal bilateral infusion of LPS (40 µg/side) soon after the period of exercise. Table S8. Eight weeks (W) of strength exercise (three not tested weeks of adaptation plus five ones of training, which test is showed in this figure) previously to the intra-CAI dorsal bilateral infusion of LPS (40 µg/side), or saline improved the muscular strength of the animals. Table S9. Eight weeks of strength exercise prior to the intra-CA1 dorsal bilateral infusion of LPS (40 µg/side) does not affect rats' locomotion and exploratory activity in the open field task. Table S10. Eight weeks of strength exercise previously to the itra-CA1 dorsal bilateral infusion of LPS (40 µg/side) does not affect the nociception of rats in the hot plate task (DOCX 61 KB)