cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A geometric method to determine the direction of electric field due to a uniformly charged line segment
Creators: name: Zuo, Fulin
Publisher: name: arXiv
Year: 2014
Subjects: subject: Popular Physics (physics.pop-ph)
subject: FOS: Physical sciences

description: A geometrical approach to calculate the electric field due to a uniformly charged rod is presented. The result is surprisingly simple and elegant. Using pure geometrical quantities like length and angle, the direction of the electric field in this charge configuration can be graphically defined. Understanding and application of this result can lead to a deeper appreciation of symmetry in a seemingly unsymmetric system.
Cerebrospinal fluid is an efficient route for establishing brain infection with feline immunodeficiency virus and transfering infectious virus to the periphery
Creators: name: Hudson, Lola
name: Liu, Pinghuang
name: Tompkins, Mary
name: Rundle, Cyndi
name: Vahlenkamp, Thomas
name: Meeker, Rick
name: Colby, Brenda
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: Like human immunodeficiency virus (HIV), feline immunodeficiency virus (FIV) invades and infects the central nervous system (CNS) soon after peripheral infection. The appearance of viral RNA is particularly prominent in the cerebrospinal fluid (CSF), suggesting an efficient route of virus transfer across the blood-CSF barrier. This raises the concern whether this route can establish a stable viral reservoir and also be a source of virus capable of reseeding peripheral systems. To examine this possibility, 200 μl of cell-free NCSU1 FIV or FIV-infected choroid plexus macrophages (ChP-Mac) was directly injected into the right lateral ventricle of the brain. Negative controls were sham inoculated with uninfected ChP-Mac or virus-free culture supernatant and positive controls were infected systemically by intraperitoneal (i.p.) injection. Intracerebroventricular (i.c.v.) inoculation with cell-free FIV resulted in high levels of plasma FIV RNA detected as early as 1 to 2 weeks post inoculation in all cats. In each case, the plasma viremia preceded the detection of CSF viral RNA. Compared to i.p. cats, i.c.v. cats had 32-fold higher CSF viral loads, 8-fold higher ratios of CSF to plasma viral load, and a 23-fold greater content of FIV proviral DNA in the brain. No FIV RNA was detected in plasma or CSF from the cats inoculated with FIV-infected ChP-Mac but an acute inflammatory response and a slight suppression of the CD4+:CD8+ ratio were observed. These results indicate that free FIV circulating in the CSF promotes infection of the CNS and provides a highly efficient pathway for the transfer of infectious virus to the periphery.
LHC Optics Measurement with Proton Tracks Detected by the Roman Pots of the TOTEM Experiment
Creators: name: The TOTEM Collaboration
name: Antchev, G.
name: Aspell, P.
name: Atanassov, I.
name: Avati, V.
name: Baechler, J.
name: Berardi, V.
name: Berretti, M.
name: Bossini, E.
name: Bottigli, U.
name: Bozzo, M.
name: Brücken, E.
name: Buzzo, A.
name: Cafagna, F. S.
name: Catanesi, M. G.
name: Covault, C.
name: Csanád, M.
name: Csörgő, T.
name: Deile, M.
name: Doubek, M.
name: Eggert, K.
name: Eremin, V.
name: Ferro, F.
name: Fiergolski, A.
name: Garcia, F.
name: Georgiev, V.
name: Giani, S.
name: Grzanka, L.
name: Hammerbauer, J.
name: Heino, J.
name: Hilden, T.
name: Karev, A.
name: Kašpar, J.
name: Kopal, J.
name: Kundrát, V.
name: Lami, S.
name: Latino, G.
name: Lauhakangas, R.
name: Leszko, T.
name: Lippmaa, E.
name: Lippmaa, J.
name: Lokajíček, M. V.
name: Losurdo, L.
name: Vetere, M. Lo
name: Rodríguez, F. Lucas
name: Macrí, M.
name: Mäki, T.
name: Mercadante, A.
name: Minafra, N.
name: Minutoli, S.
name: Nemes, F.
name: Niewiadomski, H.
name: Oliveri, E.
name: Oljemark, F.
name: Orava, R.
name: Oriunno, M.
name: Österberg, K.
name: Palazzi, P.
name: Peroutka, Z.
name: Procházka, J.
name: Quinto, M.
name: Radermacher, E.
name: Radicioni, E.
name: Ravotti, F.
name: Robutti, E.
name: Ropelewski, L.
name: Ruggiero, G.
name: Saarikko, H.
name: Scribano, A.
name: Smajek, J.
name: Snoeys, W.
name: Sziklai, J.
name: Taylor, C.
name: Turini, N.
name: Vacek, V.
name: Welti, J.
name: Whitmore, J.
name: Wyszkowski, P.
name: Zielinski, K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Accelerator Physics (physics.acc-ph)
subject: High Energy Physics - Experiment (hep-ex)
subject: FOS: Physical sciences

description: Precise knowledge of the beam optics at the LHC is crucial to fulfil the physics goals of the TOTEM experiment, where the kinematics of the scattered protons is reconstructed with the near-beam telescopes -- so-called Roman Pots (RP). Before being detected, the protons' trajectories are influenced by the magnetic fields of the accelerator lattice. Thus precise understanding of the proton transport is of key importance for the experiment. A novel method of optics evaluation is proposed which exploits kinematical distributions of elastically scattered protons observed in the RPs. Theoretical predictions, as well as Monte Carlo studies, show that the residual uncertainty of this optics estimation method is smaller than 0.25 percent.
description: 20 pages, 11 figures, 5 figures, to be submitted to New J. Phys
Compartmentalization and evolution of feline immunodeficiency virus between the central nervous system and periphery following intracerebroventricular or systemic inoculation
Creators: name: Tompkins, Mary
name: Vahlenkamp, Thomas
name: Liu, Pinghuang
name: Meeker, Rick
name: Hudson, Lola
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2006

description: The emergence of distinct neuropathogenic strains resulting from the adaptation and the unique evolution of human immunodeficiency virus (HIV) in the brain may contribute to the development of HIV-induced neurological diseases. In this study, the authors tracked early changes in virus evolution and compartmentalization between peripheral tissues and the central nervous system (CNS) after intracerebroventricular (i.c.v.) or intraperitoneal (i.p.) inoculation of animals with cell-free feline immunodeficiency virus (FIV). Using the FIV-NCSU1 envelope V3–V4 heteroduplex tracking assay (HTA), the authors observed a rapid compartmentalization of envelope variants between the CNS and periphery. Animals receiving the i.c.v. inoculation showed two peaks of viral RNA in the cerebrospinal fluid (CSF) with very different HTA patterns. Compared to the initial viral peak in CSF, the second peak showed an increased compartmentalization from plasma, reduced viral diversity, and more divergence from the proviral DNA in peripheral blood mononuclear cells (PBMCs) and the choroid plexus. In contrast, changes in plasma over the same time period were small. Different animals harbored different FIV DNA genotypes with varied regional compartmentalization within the brain. These results demonstrated that the virus within the CNS experienced a relatively independent but variable evolution from the periphery. Initial penetration of virus into the CSF facilitated the development of brain-specific reservoirs and viral diversification within the CNS.
title: MR Spectroscopy Imaging in Paediatric Posterior Fossa Tumors
Creators: name: Abubacker Sulaiman, Farook
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Outcomes
subject: Localisation
subject: MR-Spectroscopy
subject: CNS

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To highlight the benefits of MRS in posterior fossa lesions. Correlating metabolite levels measured in MRS with conventional MR findings to achieve appropriate preoperative...
Asymptotics of nonparametric L-1 regression models with dependent data
Creators: name: Zhao, Zhibiao
name: Wei, Ying
name: Lin, Dennis K. J.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Statistics Theory (math.ST)
subject: FOS: Mathematics

description: We investigate asymptotic properties of least-absolute-deviation or median quantile estimates of the location and scale functions in nonparametric regression models with dependent data from multiple subjects. Under a general dependence structure that allows for longitudinal data and some spatially correlated data, we establish uniform Bahadur representations for the proposed median quantile estimates. The obtained Bahadur representations provide deep insights into the asymptotic behavior of the estimates. Our main theoretical development is based on studying the modulus of continuity of kernel weighted empirical process through a coupling argument. Progesterone data is used for an illustration.
description: Published in at http://dx.doi.org/10.3150/13-BEJ532 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm)
Second assessment of NeuroAIDS in Africa
Creators: name: Sacktor, Ned
name: Van Rie, Annelies
name: Clifford, David
name: Lalloo, Umesh
name: Clements, Janice
name: Evans, Scott
name: Merry, Concepta
name: Hosseinipour, Mina
name: Traore, Moussa
name: Robertson, Kevin
name: Hall, Colin
name: Nakasujja, Noeline
name: Kopnisky, Kathy
name: Amod, Farida
name: Liner, Jeff
name: Newton, Charles
name: Hakim, James
name: Zink, Christine
name: Holding, Penny
name: Mielke, Jens
name: Marra, Christina
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2008

description: In July of 2006, the National Institute of Mental Health (NIMH) Center for Mental Health Research on AIDS (CMHRA) sponsored the second conference on the Assessment of NeuroAIDS in Africa, which was held in Arusha, Tanzania. The conference mission was to address the regional variations in epidemiology of HIV-related neurological disorders as well as the assessment and diagnosis of these disorders. Participants discussed and presented data regarding the relevance and translation of neuroAIDS assessment measures developed in resource intensive settings and the challenges of neuro-assessment in Africa, including the applicability of current tools, higher prevalence of confounding diseases, and the complexity of diverse cultural settings. The conference presentations summarized here highlight the need for further research on neuroAIDS in Africa and methods for assessing HIV-related neurological disorders.
title: A stratified evidenced based approach to gonad shielding for paediatric patients undergoing pelvic radiography
Creators: name: McCoubrey, Siobhan
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Paediatric
subject: Radioprotection / Radiation dose
subject: Radiographers
subject: Conventional radiography
subject: Radiation safety

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Aims This study aimed to provide an evidenced based approach to paediatric gonad shielding for pelvic radiography. Radiography of the pelvis is a commonly requested examination for paediatric patients and is used to evaluate a number of hip...
Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis.
Creators: name: Howe, Marija Petrić
name: Crerar, Hamish
name: Neeves, Jacob
name: Harley, Jasmine
name: Tyzack, Giulia
name: Klein, Pierre
name: Ramos, Andres
name: Patani, Rickie
name: Luisier, Raphaëlle
Publisher: name: The Francis Crick Institute
Year: 2022
Subjects: subject: Neurosciences
subject: FOS: Clinical medicine
subject: Stem Cells
subject: Cell Biology

description: Intron retention (IR) is now recognized as a dominant splicing event during motor neuron (MN) development, however the role and regulation of intron-retaining transcripts (IRTs) localized to the cytoplasm remain particularly understudied. Here we show that IR is a physiological process that is spatiotemporally regulated during MN lineage restriction and that IRTs in the cytoplasm are detected in as many as 13% (n=2297) of the genes expressed during this process. We identify a major class of cytoplasmic IRTs, which are not associated with reduced expression of their own genes, but instead show a high capacity for RNA-binding protein and miRNA occupancy. Finally, we show that ALS-causing VCP mutations lead to a selective increase in cytoplasmic abundance of this particular class of IRTs, which in turn temporally coincides with an increase in the nuclear expression level of predicted miRNA target genes. Altogether, our study identifies a previously unrecognized class of cytoplasmic intronic sequences with potential regulatory function beyond gene expression.
title: Abdominal imaging in tropical disease
Creators: name: SRICHAROEN, THANATORN
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Infection
subject: Education
subject: CT
subject: Conventional radiography
subject: Abdomen

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: To review and illustrate abdominal imaging findings, particularly plain abdominal radiography(CR), ultrasonography(US), and computed tomography(CT), of tropical...
NeuroAIDS in Africa
Creators: name: Joseph, Jeymohan
name: Banda, Mwanza
name: Sankalé, Jean-Louis
name: Kammerer, Betsy
name: Njamnshi, Alfred
name: Kanmogne, Georgette
name: Hakim, James
name: Diop, Amadou Gallo
name: Bangirana, Paul
name: Wood, Charles
name: Holding, Penny
name: Nath, Avindra
name: Wong, Joseph
name: Adebamowo, Clement
name: Clifford, David
name: Paul, Robert
name: Langford, T. Dianne
name: Jaye, Assan
name: Van Rie, Annelies
name: Robertson, Kevin
name: Letendre, Scott
name: Royal III, Walter
name: Hosseinipour, Mina
name: Joska, John
name: Sacktor, Ned
name: Lawler, Kathy
name: Liner, Jeff
name: Boivin, Michael
name: Nakasuja, Noeline
name: Grant, Igor
name: Ive, Prudence
name: Weyessa, Tufa Gemechu
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2010

description: In July 2009, the Center for Mental Health Research on AIDS at the National Institute of Mental Health organized and supported the meeting “NeuroAIDS in Africa.” This meeting was held in Cape Town, South Africa, and was affiliated with the 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention. Presentations began with an overview of the epidemiology of HIV in sub-Saharan Africa, the molecular epidemiology of HIV, HIV-associated neurocognitive disorders (HANDs), and HAND treatment. These introductory talks were followed by presentations on HAND research and clinical care in Botswana, Cameroon, Ethiopia, The Gambia, Kenya, Malawi, Nigeria, Senegal, South Africa, Uganda, and Zambia. Topics discussed included best practices for assessing neurocognitive disorders, patterns of central nervous system (CNS) involvement in the region, subtype-associated risk for HAND, pediatric HIV assessments and neurodevelopment, HIV-associated CNS opportunistic infections and immune reconstitution syndrome, the evolving changes in treatment implementation, and various opportunities and strategies for NeuroAIDS research and capacity building in the region.
Relativistic Boltzmann transport approach with Bose-Einstein statistics and the onset of gluon condensation
Creators: name: Scardina, F.
name: Perricone, D.
name: Plumari, S.
name: Ruggieri, M.
name: Greco, V.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Nuclear Theory (nucl-th)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study the evolution of a gluon system under conditions of density and temperature similar to those explored in the early stage of ultra-relativistic heavy-ion collisions. We first describe the implementation of Relativistic Boltzmann-Nordheim (RBN) transport approach that includes in the collision integral the quantum effects of Bose-Einstein Statistics. Then, we describe the evolution of a spatially uniform gluon system in a box under elastic collisions solving the RBN for various initial conditions. We discuss the critical phase-space density that leads to the onset of a Bose-Einstein condensate (BEC) and the time scale for this process to occur. In particular, thanks to the fact that RBN allows to relax the small angle approximation, we study the effect at both small and large screening mass $ m_{D} $. For small $ m_{D}\ll T $ we see that our solution of RBN is in agreement with the recent extensive studies within a Fokker-Planck scheme in small angle approximation. For the same total cross section but with large $ m_{D}\simeq 2\, T $ (large angle scatterings), we see a significant time speed-up of the onset of BEC respect to small $m_{D}\ll T$. This further strengthen the possibility that at least a transient BEC is formed in the early stage of ultra-relativistic heavy-ion collisions.
description: 12 pages, 15 figures
Introduction: Emerging Directions for Family History Studies
Creators: name: Evans, Tanya
name: De Groot, Jerome
Publisher: name: T. Evans, J. de Groot, Introduction: Emerging Directions for Family History Studies, «International Public History», 2, 2019, n. 2, pp. 1-3
Year: 2019
Subjects: Family history
Public history
Genealogy
DNA
Glocal
Collaboration

description: This introduction charts the rise of family history across the globe and its international impact upon culture, biomedicine, and technology. It introduces the contributions to this special issue from interdisciplinary scholars based in the US, Canada, Brazil, Europe, Australia and India that have collaborated internationally over the past three years. It argues that public historians need to take the practice of family history seriously and that all scholars can learn from its collaborative, integrated, international practice. We are presented with overwhelming evidence of the need to decentralize and trouble the Eurocentrism of existing historical scholarship. This special issue provides a platform for the conversations we have been having about family history over the past three years and encourages others to join in.
Challenges in obsolescence management and system engineering using the example of the German supplier industry
Creators: name: Winzer, Janis
name: Wagner, Eduard
name: Benecke, Stephan
name: Nissen, Nils F.
name: Lang, Klaus‐Dieter
Publisher: name: Technische Universität Berlin
Year: 2021
Subjects: subject: 500 Naturwissenschaften und Mathematik
subject: 600 Technik, Technologie
subject: 300 Sozialwissenschaften
subject: obsolescence
subject: product lifetime
subject: electronic components
subject: components obsolescence group
subject: eco-reliability
subject: eco-design

description: Obsolescence, in the sense of short lifetime of predominantly electronic products, is increasingly becoming a problem for industrial processes and ultimately for the community. The number of cases in which professional customers want to buy products, which are no longer available for purchase is steadily increasing. In the industrial setting this situation leads to strategies, which are necessary but actually undesired, in order to be able to maintain the business activities. Basically, more money and time has to be spent on countering obsolescence. In order to better meet these challenges, enabling people to exchange ideas with like-minded colleagues, who are in the same situation, and to jointly develop strategies for solution processes, an interest group driven primarily by the electronics industry has been founded under the name Component Obsolescence Group Germany (COG-D). The purpose of this paper is to describe the current state of affairs regarding Obsolescence Management (hereinafter referred as OM). OM in the sense of dealing with obsolete or discontinued components is not completely new, but the problem has increased significantly in recent years, which makes it interesting to take a closer look at the reasons in order to derive solutions. The findings are based on a survey taken among the members of the COG-D.
Completion of planar sensor production for ACF
Creators: name: G.Calderini
name: D.Dannheim
name: J.Schmidt
name: P.Svihra
name: M.Vicente
name: M. Centis Vignali
name: M. Boscardin
Publisher: name: Zenodo
Year: 2022
Subjects: WP6

description: Planar sensors and dedicated test structures are necessary for a precise characterisation of the ACF bonding developed in the framework of the Task 6.4 (WP6) of AIDAInnova. This document reports on the production and availability of such devices and the completion of MS24 in Month 18.
title: Die NATO-Ostflanke zwischen Abrüstung und Aufrüstung / Karte: Bernd Nogli ; Text: Erwin Teichmann
Creators: name: Teichmann, Erwin
Publisher: name: ZMSBw
Year: 2023

description: Die aktuelle Karte : historische Ereignisse in Kartenansicht / Zentrum für Militärgeschichte und Sozialwissenschaften der Bundeswehr; [12]
title: Grading lumbar disc degeneration: a comparison between low- and high-field MRI
Creators: name: Ciochon, Urszula
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Musculoskeletal spine
subject: MR
subject: Observer performance
subject: Technical aspects

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: Magnetic resonance imaging (MRI) of the lumbar spine is often requested to identify the possible pain source in patients with non-specific low back pain (LBP). Degenerative MRI findings in the lumbar spine are common in both individuals with and...
Approximation algorithms for the Transportation Problem with Market Choice and related models
Creators: name: Aardal, Karen
name: Bodic, Pierre Le
Publisher: name: arXiv
Year: 2014
Subjects: subject: Data Structures and Algorithms (cs.DS)
subject: FOS: Computer and information sciences

description: Given facilities with capacities and clients with penalties and demands, the transportation problem with market choice consists in finding the minimum-cost way to partition the clients into unserved clients, paying the penalties, and into served clients, paying the transportation cost to serve them. We give polynomial-time reductions from this problem and variants to the (un)capacitated facility location problem, directly yielding approximation algorithms, two with constant factors in the metric case, one with a logarithmic factor in the general case.
title: Αξιολόγηση των υπηρεσιών ηλεκτρονικής διακυβέρνησης στις χώρες της Ευρωπαϊκής Ένωσης

title: Evaluation of e-government services in EU countries
Creators: name: Ψαρακη Αικατερινη
Publisher: name: Technical University of Crete
Year: 2023

description: Η παρούσα εργασία πραγματεύεται το ζήτημα της αξιολόγησης της ηλεκτρονικής
διακυβέρνησης για τις χώρες της Ευρωπαϊκής Ένωσης. Η Δημόσια Διοίκηση μέσω της ηλεκτρονικής διακυβέρνησης στοχεύει να φέρει τις κυβερνήσεις πιο κοντά στους πολίτες και τις επιχειρήσεις, μέσω της υιοθέτησης στρατηγικών προσεγγίσεων στη χρήση της τεχνολογίας και την ψηφιακή παροχή υπηρεσιών. Η ηλεκτρονική διακυβέρνηση έχει ως βασικό στόχο τον επαναπροσδιορισμό και τον μετασχηματισμό των εσωτερικών και εξωτερικών σχέσεων του Δημόσιου τομέα με τη χρήση σύγχρονων μέσων και τεχνολογιών. Για την αξιολόγηση της
ηλεκτρονικής διακυβέρνησης των Ευρωπαϊκών χωρών και την διεξαγωγή αποτελεσμάτων και συμπερασμάτων  γίνεται εφαρμογή της πολυκριτηριακής μεθόδου PROMETHEE η οποία βασίζεται στη θεωρία των σχέσεων υπεροχής και αξιοποιεί τη διαδικασία διμερών συγκρίσεων των εναλλακτικών που παρουσιάζονται. Η εφαρμογή της πολυκριτηριακής μεθόδου γίνεται στα αποτελέσματα της έκθεσης συγκριτικής αξιολόγησης της ηλεκτρονικής διακυβέρνησης του 2022 (Ευρωπαϊκή Επιτροπή), που περιέχουν δεδομένα των κρατών μελών της ΕΕ, με σκοπό την επισκόπηση της κατάστασής τους και της ποιότητας των παρεχόμενων υπηρεσιών προς τους πολίτες.
La niña de Gómez Arias
Creators: name: Antonucci, Fausta
Publisher: name: Zenodo
Year: 2023
Subjects: Calderón
Métrica dramática
Segmentación dramática
Bibliografía
La niña de Gómez Arias

description: Calderón Digital: base de datos, argumentos y motivos del teatro de Calderón (dir. Fausta Antonucci). Ficha dedicada a La niña de Gómez Arias, con datos bibliográficos primarios y secundarios, fecha probable de composición, cómputo de las formas métricas, análisis de las coordenadas espacio-temporales, adscripción genérica y sinopsis argumental detallada, con indicación de los principales motivos (diegéticos y simbólicos) y propuesta de segmentación articulada según los cambios de forma métrica, de espacio y tiempo dramáticos.
File S1 - prophages_phaster_939_sequences.fasta
Creators: name: Morgan, Tulio
Publisher: name: figshare
Year: 2022
Subjects: subject: 60506 Virology
subject: FOS: Biological sciences
subject: Computational Biology
subject: 60102 Bioinformatics
subject: FOS: Computer and information sciences

description: Fasta sequences of the putative Erwinia prophages detected using PHASTER tool
A multinational study of neurological performance in antiretroviral therapy-naïve HIV-1-infected persons in diverse resource-constrained settings
Creators: name: Jiang, Jeanne H.
name: La Rosa, Alberto
name: Hall, Colin
name: Masih, Reena
name: Robertson, Kevin
name: Evans, Scott
name: Hakim, James
name: Marra, Christina M.
name: Kanyama, Cecilia
name: Silva, Marcus T.
name: Santos, Breno
name: Price, Richard W.
name: Supparatpinyo, Khuanchai
name: Murphy, Robert
name: Hosseinipour, Mina
name: Berzins, Baiba
name: Kumarasamy, N.
name: Tripathy, Srikanth
name: Amod, Farida
name: Nair, Apsara
name: Brouwers, Pim
name: Campbell, Thomas B.
name: Montano, Silvia
name: Marcus, Cheryl
name: Firnhaber, Cindy
name: Sanne, Ian
name: Kumwenda, Johnstone
name: Walawander, Ann
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: Little is known about how the prevalence and incidence of neurological disease in HIV-infected patients in resource-limited settings. We present an analysis of neurological and neurocognitive function in antiretroviral naïve individuals in multinational resource-limited settings.
title: Deutschland 1923: das Jahr am Abgrund / Text: Christoph Kuhl ; gelesen von: Heiner Möllers
Creators: name: Kuhl, Christoph
Publisher: name: ZMSBw
Year: 2023

description: Rezension von: Ullrich, Volker Deutschland 1923 : das Jahr am Abgrund / Volker Ullrich. - München : C.H.Beck, [2022]. - 441 Seiten : Illustrationen. - Literaturverzeichnis: Seite 419-431. ISBN 978-3-406-79103-1
description: Buchjournal: Angelesen. : das Buchjournal des ZMSBw / Zentrum für Militärgeschichte und Sozialwissenschaften der Bundeswehr; [39]
Protein changes in CSF of HIV-infected patients: evidence for loss of neuroprotection
Creators: name: Hall, Colin
name: Markovic-Plese, Silva
name: Meeker, Rick B.
name: Robertson, Kevin
name: Poulton, Winona
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2011

description: To begin to unravel the complexity of HIV-associated changes in the brain, broader, multifaceted analyses of cerebrospinal fluid (CSF) are needed that examine a wide range of proteins reflecting different functions. CSF from HIV-infected patients with a range of cognitive deficits was compared to CSF from uninfected, cognitively normal patients to begin to identify protein changes associated with HIV infection and neurological disease progression. Uninfected patients showed relatively consistent patterns of protein expression. Highly expressed proteins in CSF included monocyte chemotactic protein-1, tissue inhibitors of metalloproteases, granulocyte colony-stimulating factor, adiponectin, soluble tumor necrosis factor receptor-1, urokinase-type plasminogen activator receptor, and insulin-like growth factor binding protein-2. Inflammatory and anti-inflammatory cytokines were expressed at low levels. HIV-infected patients showed increases in inflammatory proteins (interferon-gamma, tumor necrosis factor-alpha), anti-inflammatory proteins (IL-13), and chemokines but these correlated poorly with neurological status. The strongest correlation with increasing severity of neurological disease was a decline in growth factors, particularly, brain-derived neurotrophic factor and NT-3. These studies illustrate that HIV infection is associated with parallel changes in both inflammatory and neuroprotective proteins in the CSF. The inverse relationship between growth factors and neurological disease severity suggests that a loss of growth factor neuroprotection may contribute to the development of neural damage and may provide useful markers of disease progression.
Dynamic generation of photonic spatial quantum states with an all-fiber platform
Creators: name: Alarcón, A.
name: Argillander, J.
name: Spegel-Lexne, D.
name: Xavier, G. B.
Publisher: name: arXiv
Year: 2023
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Photonic spatial quantum states are a subject of great interest for applications in quantum communication. One important challenge has been how to dynamically generate these states using only fiber-optical components. Here we propose and experimentally demonstrate an all-fiber system that can dynamically switch between any general transverse spatial qubit state based on linearly polarized modes. Our platform is based on a fast optical switch based on a Sagnac interferometer combined with a photonic lantern and few-mode optical fibers. We show switching times between spatial modes on the order of 5 ns and demonstrate the applicability of our scheme for quantum technologies by demonstrating a measurement-device-independent (MDI) quantum random number generator based on our platform. We run the generator continuously over 15 hours, acquiring over 13.46 Gbits of random numbers, of which we ensure that at least 60.52% are private, following the MDI protocol. Our results show the use of photonic lanterns to dynamically create spatial modes using only fiber components, which due to their robustness and integration capabilities, have important consequences for photonic classical and quantum information processing.
description: 11 pages, 4 figures
title: Diagnostic performance of tomosynthesis for the diagnosis of hip prosthetic loosening compared to radiography and CT with metal artifact reduction: a prospective study.
Creators: name: Gillet, Romain
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Prostheses
subject: Diagnostic procedure
subject: CT
subject: Conventional radiography
subject: Musculoskeletal system
subject: Musculoskeletal joint
subject: Musculoskeletal bone

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: The aim of this study was to evaluate the diagnostic performance of tomosynthesis for the diagnosis of hip prosthesis loosening (PL) compared to radiography and CT with metal artifact reduction...
Antiretroviral neurotoxicity
Creators: name: Robertson, Kevin
name: Meeker, Rick B.
name: Liner, Jeff
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2012

description: Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV burden, however, poor penetration into the central nervous system (CNS) provides incomplete protection. Although the severity of HIV-associated neurocognitive disorders (HAND) has been reduced, neurological disease is expected to exert an increasing burden as HIV-infected patients live longer. Strategies to enhance penetration of antiretroviral compounds into the CNS could help to control HIV replication in this reservoir but also carries an increased risk of neurotoxicity. Efforts to target antiretroviral compounds to the CNS will have to balance these risks against the potential gain. Unfortunately, little information is available on the actions of antiretroviral compounds in the CNS, particularly at concentrations that provide effective virus suppression. The current studies evaluated the direct effects of 15 anti-retroviral compounds on neurons to begin to provide basic neurotoxicity data that will serve as a foundation for the development of dosing and drug selection guidelines. Using sensitive indices of neural damage, we found a wide range of toxicities, with median toxic concentrations ranging from 2 to 10,000 ng/ml. Some toxic concentrations overlapped concentrations currently seen in the CSF but the level of toxicity was generally modest at clinically relevant concentrations. Highest neurotoxicities were associated with abacavir, efavarenz, etravirine, nevaripine, and atazanavir, while the lowest were with darunavir, emtracitabine, tenofovir, and maraviroc. No additive effects were seen with combinations used clinically. These data provide initial evidence useful for the development of treatment strategies that might reduce the risk of antiretroviral neurotoxicity.
The quiescent state of the accreting X-ray pulsar SAX J2103.5+4545
Creators: name: Reig, P.
name: Doroshenko, V.
name: Zezas, A.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Solar and Stellar Astrophysics (astro-ph.SR)
subject: High Energy Astrophysical Phenomena (astro-ph.HE)
subject: FOS: Physical sciences

description: We present an X-ray timing and spectral analysis of the Be/X-ray binary SAX J2103.5+4545 at a time when the Be star's circumstellar disk had disappeared and thus the main reservoir of material available for accretion had extinguished. In this very low optical state, pulsed X-ray emission was detected at a level of L_X~10^{33} erg/s. This is the lowest luminosity at which pulsations have ever been detected in an accreting pulsar. The derived spin period is 351.13 s, consistent with previous observations. The source continues its overall long-term spin-up, which reduced the spin period by 7.5 s since its discovery in 1997. The X-ray emission is consistent with a purely thermal spectrum, represented by a blackbody with kT=1 keV. We discuss possible scenarios to explain the observed quiescent luminosity and conclude that the most likely mechanism is direct emission resulting from the cooling of the polar caps, heated either during the most recent outburst or via intermittent accretion in quiescence.
description: 7 pages, 2 Tables, 7 figures. Accepted for publication in MNRAS
Decreased MEG beta oscillations in HIV-infected older adults during the resting state
Creators: name: Heinrichs-Graham, Elizabeth
name: Becker, Katherine M.
name: Wilson, Tony W.
name: O’Neill, Jennifer
name: Fox, Howard S.
name: Swindells, Susan
name: Sandkovsky, Uriel
name: Robertson, Kevin R.
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: The introduction of combination antiretroviral therapy significantly reduced the prevalence of the most severe form of HIV-associated neurocognitive disorders (HAND). Despite this decline, 35–70% of HIV-infected patients continue to develop mild motor and cognitive impairments. Although neuropsychological studies have shown that HAND affects a wide array of cognitive functions, a formal diagnosis is still based on the exclusion of opportunistic infections and other common ailments, as no specific tests or biomarkers are currently available. In this study, we used magnetoencephalography (MEG) to measure neural activity during the resting-state in 15 HIV-infected older patients and a demographically-matched group of 15 uninfected controls. MEG is a noninvasive and direct measure of neural activity with excellent spatiotemporal resolution. All MEG data were coregistered to structural MRI, corrected for head motion, fitted to a regional-level source model, and subjected to spectral analyses to quantify population-level neural oscillatory activity. We found that HIV-infected persons exhibited decreased beta oscillations in the supplementary motor area bilaterally, paracentral lobule, posterior cingulate, and bilateral regions of the superior parietal lobule relative to healthy controls. Beta oscillations in the posterior cingulate, a critical component of the default mode network, were also positively correlated with patient scores on the memory recall aspect of the Hopkins Verbal Learning Test-Revised. These results demonstrate that chronic HIV infection does not uniformly disturb cortical function, and that neuronal populations in dorso-medial motor and parietal cortices are especially affected. These findings also suggest that resting-state MEG recordings may hold significant promise as a functional biomarker for identifying HAND and monitoring disease progression.
Activity-induced clustering in model dumbbell swimmers: The role of hydrodynamic interactions
Creators: name: Furukawa, Akira
name: Marenduzzo, Davide
name: Cates, Michael E
Publisher: name: arXiv
Year: 2014
Subjects: subject: Soft Condensed Matter (cond-mat.soft)
subject: FOS: Physical sciences

description: Using a fluid-particle dynamics approach, we numerically study the effects of hydrodynamic interactions on the collective dynamics of active suspensions within a simple model for bacterial motility: each microorganism is modeled as a stroke-averaged dumbbell swimmer with prescribed dipolar force pairs. Using both simulations and qualitative arguments, we show that, when the separation between swimmers is comparable to their size, the swimmers' motions are strongly affected by activity-induced hydrodynamic forces. To further understand these effects, we investigate semidilute suspensions of swimmers in the presence of thermal fluctuations. A direct comparison between simulations with and without hydrodynamic interactions shows these to enhance the dynamic clustering at a relatively small volume fraction; with our chosen model the key ingredient for this clustering behavior is hydrodynamic trapping of one swimmer by another, induced by the active forces. Furthermore, the density dependence of the motility (of both the translational and rotational motions) exhibits distinctly different behaviors with and without hydrodynamic interactions; we argue that this is linked to the clustering tendency. Our study illustrates the fact that hydrodynamic interactions not only affect kinetic pathways in active suspensions, but also cause major changes in their steady state properties.
description: 18 pages, 14 figures
title: “ABCs approach of polytraumatized patients: emphasis of CT imaging findings”
Creators: name: Mellou, Vasiliki
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Abdomen
subject: Emergency
subject: Trauma
subject: CT
subject: Education
subject: eLearning
subject: Haemorrhage
subject: Trauma

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: 1.List imaging findings of important injuries. 2.Delineate the spectrum of insidious findings in the trauma setting. 3.Present a systematic approach in order not to overlook significant...
Global NeuroAIDS Roundtable
Creators: name: Smith, Davey M.
name: Joseph, Jeymohan
name: Robertson, Kevin
name: Sithinamsuwan, Pasiri
name: Paul, Robert H.
name: Valcour, Victor
name: Boivin, Michael J.
name: Ellis, Ronald J.
name: Letendre, Scott
name: Brew, Bruce J.
name: Marcotte, Thomas D.
name: Sacktor, Ned
name: Wood, Charles
name: Pulliam, Lynn
name: Clifford, David B.
name: Wigdahl, Brian
name: Royal, Walter
name: Nath, Avindra
name: Heaton, Robert K.
name: Kanmogne, Georgette D.
name: Pardo, Carlos A.
name: Grant, Igor
name: Achim, Cristian L.
name: Gallo-Diop, Amadou
name: Colosi, Deborah A.
name: Kumar, Mahendra
Publisher: name: The University of North Carolina at Chapel Hill University Libraries
Year: 2013

description: In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the “Global NeuroAIDS Roundtable” in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought together NIMH-funded investigators who are currently working on projects related to the neurological complications of AIDS (NeuroAIDS) in Africa, Asia, Eastern Europe, and Latin America in order to provide an opportunity to share their recent findings and discuss the challenges encountered within each country. The major goals of the roundtable were to evaluate HIV-associated neurocognitive impairment and determine if it may be directly attributable to distinct HIV subtypes or clades and to discuss the future priorities for global NeuroAIDS research. At the “Global NeuroAIDS Roundtable”, presentations of preliminary research indicated that HIV-associated neurocognitive impairment is prevalent in all countries examined regardless of which HIV clade is present in the region. The only clear-cut difference between HIV-1 clades was in relation to subtypes A and D in Uganda. However, a key point that emerged from the discussions was that there is an urgent need to standardize neurocognitive assessment methodologies across the globe before definitive conclusions can be drawn regarding the relationship between HIV clade diversity and neuropathogenesis. Future research directions were also discussed at the roundtable with particular emphasis on the potential of viral and host factor molecular interactions to impact the pathophysiology of HIV-associated neurocognitive disorders (HAND) from a global perspective.
Stochasticity, periodicity and coherent structures in partially mode-locked fibre lasers
Creators: name: Churkin, Dmitry
name: Sugavanam, Srikanth
name: Tarasov, Nikita
name: Khorev, Serge
name: Smirnov, Sergey V.
name: Kobtsev, Sergey M.
name: Turitsyn, Sergei K.
Publisher: name: arXiv
Year: 2014
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Physical systems with co-existence and interplay of processes featuring distinct spatio-temporal scales are found in various research areas ranging from studies of brain activity to astrophysics. Complexity of such systems makes their theoretical and experimental analysis technically and conceptually challenging. Here, we discover that radiation of partially mode-locked fibre lasers, while being stochastic and intermittent on short time scale, exhibits periodicity and long scale correlations over slow evolution from one round trip to another. The evolution mapping of intensity auto-correlation function allows us to reveal variety of spatio-temporal coherent structures and to experimentally study their symbiotic co-existence with stochastic radiation. Our measurements of interactions of noisy pulses over a time scale of thousands of non-linear lengths demonstrate that they have features of incoherent temporal solitons. Real-time measurements of spatio-temporal intensity dynamics are set to bring new insight into rich underlying nonlinear physics of practical active- and passive-cavity photonic systems.
title: Role of susceptibility weighted imaging in cerebro-pontine angle schwannoma Vs meningiomas.
Creators: name: SARAVANAN, K
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Outcomes
subject: Localisation
subject: MR
subject: CNS

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Tolearn differentiating features of vestibular schwannoma from meningioma byMR susceptibility weighted...
title: Checking pregnancy status of young girls in advance of radiological intervention: time for a re-think?
Creators: name: Murphy, Dara
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Paediatric
subject: Radioprotection / Radiation dose
subject: Foetal imaging
subject: CT
subject: Conventional radiography
subject: Nuclear medicine conventional
subject: Education

description: Aims and objectives Methods and materials Results Conclusion Personal information References
description: Aims and objectives: We propose that the need to establish the pregnancy status of paediatric patients, in advance of radiological examination, be based on the prevalence of pregnancy in that population, rather than an arbitrary age range of 12 and older, commonly...
Mapping Moving Makers: Mobility in the British Scientific Instrument Trade, 1700-1900 (Abstract)
Creators: name: Hay, Duncan
name: Butterworth, Alex
name: Middle, Sarah
name: Higitt, Rebekah
Publisher: name: Zenodo
Year: 2022

description: Abstract for 'Mapping Moving Makers: Mobility in the British Scientific Instrument Trade, 1700-1900'
title: Osteoma Osteoid: the great mimicker
Creators: name: Carneiro, Bruno
Publisher: name: European Congress of Radiology
Year: 2018
Subjects: subject: Musculoskeletal system
subject: CT
subject: MR
subject: Diagnostic procedure
subject: Neoplasia

description: Learning objectives Background Findings and procedure details Conclusion Personal information References
description: Learning objectives: Display several atypical forms of clinical and radiological presentation of Osteoid Osteoma (OO), which mimic other conditions, showing how it is possible to differentiate them. Also show the OO-mimicking lesions that may lead to diagnostic...
title: Area management: A change of mind? A critical examination of area management in local government
Creators: name: Paterson, Alan J.
Publisher: name: University of Glasgow
Year: 1980
Subjects: subject: Urban planning, public administration.

description: The dissertation is structured as follows. Chapter one discusses the development, evolution and nature of corporate planning, ending with a critique of this approach in local government organisation. Chapter two then goes on to discuss the evolution and potential of area management in local government. Essentially chapters one and two suggest that both these approaches are interlinked in terms of their development, how they are perceived and problems. Chapter three follows this by stressing the importance of officers and councillors in local government, in terms of how they perceive the above approaches. It then goes on to examine the problems that these key actors face in their work; how corporate planning has done little to solve them; and how area management can tackle some of these problems and perhaps enhance the roles of both officer and councillor. The first three chapters provide the theoretical background for the empirical nature of the second half of the dissertation. Chapter four examines three area management schemes in operation today - area organisation in Stockport, the Priority Areas Programme in Newcastle-upon-Tyne and area management in Dudley. These are examined separately indicating their nature, structure, organisation and objectives along with their relationship to the wider corporate system within the local authority. Chapter 5 continues on from this and discusses seven themes found to be important in area management, in relation to the three case studies. The role of the councillor and the importance of commitment in area management are examples of the themes discussed. Chapter 4 and 5 essentially provide the evidence to allow me to develop area management proposals for Strathclyde Region in chapter 6. On the basis of these earlier findings the suggested proposals are designed to solve many of the problems found to be in existence in the case study schemes.