cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Fast and Precise 3D Computation of Capacitance of Parallel Narrow Beam MEMS Structures
Creators: name: Majumdar, N.
name: Mukhopadhyay, S.
Publisher: name: arXiv
Year: 2007
Subjects: subject: Computational Physics (physics.comp-ph)
subject: General Physics (physics.gen-ph)
subject: FOS: Physical sciences

description: Efficient design and performance of electrically actuated MEMS devices necessitate accurate estimation of electrostatic forces on the MEMS structures. This in turn requires thorough study of the capacitance of the structures and finally the charge density distribution on the various surfaces of a device. In this work, nearly exact BEM solutions have been provided in order to estimate these properties of a parallel narrow beam structure found in MEMS devices. The effect of three-dimensionality, which is an important aspect for these structures, and associated fringe fields have been studied in detail. A reasonably large parameter space has been covered in order to follow the variation of capacitance with various geometric factors. The present results have been compared with those obtained using empirical parametrized expressions keeping in view the requirement of the speed of computation. The limitations of the empirical expressions have been pointed out and possible approaches of their improvement have been discussed.
description: Expanded version of the paper published in the Proceedings of International Conference on Emerging Mechanical Technology - Macro to Nano (EMTM2N-2007), February 16-18, 2007, BITS, Pilani, India
Halcón peregrino – Falco peregrinus Tunstall, 1771
Creators: name: Zuberogoitia, Íñigo
name: Salvador Milla, Alfredo
Publisher: name: Salvador Milla, Alfredo
Year: 2016

description: Aves - Orden Falconiformes - Familia Falconidae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/. Versiones anteriores: 21-06-2005; 8-03-2007; 10-03-2008; 30-07-2012
description: A comprehensive review of the natural history of the Peregrine falcon Falco peregrinus in Spain.
Negligible risk of prenatal ductus arteriosus closure or fetal renal impairment after third‐trimester paracetamol use: evaluation of the German Embryotox cohort
Creators: name: Dathe, Katarina
name: Frank, Johanna
name: Padberg, Stephanie
name: Hultzsch, Stefanie
name: Meixner, Katja
name: Beck, Evelin
name: Meister, Reinhard
name: Schaefer, Christof
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: closure of ductus arteriosus Botalli
subject: ductus arteriosus
subject: fetal renal impairment
subject: fetus
subject: oligohydramnios
subject: paracetamol (acetaminophen)
subject: persistent fetal circulation
subject: third trimester of pregnancy
subject: stillbirth
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Objective: Risk of fetotoxicity after paracetamol exposure in the third trimester. Design: Observational cohort study and retrospective case assessment. Setting: Germany, 2008-2017. Population: Pregnant women exposed to paracetamol. Methods: Prospectively enrolled third-trimester pregnancies that had been exposed to paracetamol (604) were compared with pregnancies exposed to paracetamol in the first and/or second trimester only (1192). Exclusion criteria were exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) in the second or third trimester. Additionally, the Embryotox 'adverse drug reaction in pregnancy' database was screened for cases of fetotoxicity. Main outcome measures: The prenatal study end points focused on narrowing or closure of ductus arteriosus Botalli, late fetal death, and oligohydramnios. The postnatal end points included patent ductus arteriosus (PDA), primary pulmonary hypertension (PPHT), and impaired renal function. Results: In both cohorts, no fetus with intrauterine narrowing or closure of the ductus arteriosus Botalli was reported (0/604 versus 0/1192). Oligohydramnios was diagnosed at a similar frequency in both cohorts: 1.3% (8/604) versus 1.6% (19/1192). There was one stillbirth in the study cohort (1/604, 0.2%) and four stillbirths in the comparison cohort (4/1192, 0.3%). The rates of PDA in neonates were similar: 0.7% (4/615) versus 0.7% (9/1212). PPHT as well as serious postnatal renal disorders were reported once in each cohort. In 12 out of 96 retrospective cases, there were indicators for study end points; however, co-exposure to NSAIDs or complex situations weaken the assumption of paracetamol toxicity. Conclusions: Fetal cardiovascular or renal toxicity of maternal third-trimester paracetamol use appears to be negligible. Tweetable abstract: Paracetamol use in the third trimester does not seem to be associated with a relevant risk of fetotoxicity.
Improved semiclassical model for real time evaporation of Matrix black holes
Creators: name: Berenstein, David
name: Guan, Yueshu
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We study real time classical matrix mechanics of a simplified $2\times 2$ matrix model inspired by the black hole evaporation problem. This is a step towards making a quantitative model of real time evaporation of a black hole, which is realized as a bound state of D0-branes in string theory. The model we study is the reduction of Yang Mills in $2+1$ dimension to $0+1$ dimensions, which has been corrected with an additional potential that can be interpreted as a zero point energy for fermions. Our goal is to understand the lifetime of such a classical bound state object in the classical regime. To do so, we pay particular attention to when D-particles separate to check that the "off diagonal modes" of the matrices become adiabatic and use that information to improve on existing models of evaporation. It turns out that the naive expectation value of the lifetime with the fermionic correction is infinite. This is a logarithmic divergence that arises from very large excursions in the separation between the branes near the threshold for classical evaporation. The adiabatic behavior lets us get some analytic control of the dynamics in this regime to get this estimate. This divergence is cutoff in the quantum theory due to quantization of the adiabatic parameter, resulting in a long lifetime of the bound state, with a parametric dependence of order $\log(1/\hbar)$.
description: 17 pages, 4 figures. v2: added references
Additional file 1 of The association between the body roundness index and the risk of colorectal cancer: a cross-sectional study
Creators: name: Gao, Wenxing
name: Jin, Lujia
name: Li, Dingchang
name: Zhang, Yue
name: Zhao, Wen
name: Zhao, Yingjie
name: Gao, Jingwang
name: Zhou, Lin
name: Chen, Peng
name: Dong, Guanglong
Publisher: name: figshare
Year: 2023
Subjects: subject: Biotechnology
subject: Environmental Sciences not elsewhere classified
subject: Sociology
subject: FOS: Sociology
subject: Biological Sciences not elsewhere classified
subject: Cancer
subject: Science Policy

description: Supplementary Material 1
Full counting statistics for transport through a molecular quantum dot magnet
Creators: name: Imura, Ken-Ichiro
name: Utsumi, Yasuhiro
name: Martin, Thierry
Publisher: name: arXiv
Year: 2006
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: Full counting statistics (FCS) for the transport through a molecular quantum dot magnet is studied theoretically in the incoherent tunneling regime. We consider a model describing a single-level quantum dot, magnetically coupled to an additional local spin, the latter representing the total molecular spin s. We also assume that the system is in the strong Coulomb blockade regime, i.e., double occupancy on the dot is forbidden. The master equation approach to FCS introduced in Ref. [12] is applied to derive a generating function yielding the FCS of charge and current. In the master equation approach, Clebsch-Gordan coefficients appear in the transition probabilities, whereas the derivation of generating function reduces to solving the eigenvalue problem of a modified master equation with counting fields. To be more specific, one needs only the eigenstate which collapses smoothly to the zero-eigenvalue stationary state in the limit of vanishing counting fields. We discovered that in our problem with arbitrary spin s, some quartic relations among Clebsch-Gordan coefficients allow us to identify the desired eigenspace without solving the whole problem. Thus we find analytically the FCS generating function in the following two cases: i) both spin sectors lying in the bias window, ii) only one of such spin sectors lying in the bias window. Based on the obtained analytic expressions, we also developed a numerical analysis in order to perform a similar contour-plot of the joint charge-current distribution function, which have recently been introduced in Ref. [13], here in the case of molecular quantum dot magnet problem.
description: 17 pages, 5 figures
Culebra de cogulla argelina – Macroprotodon cucullatus (Geoffroy-Saint-Hilaire, 1827)
Creators: name: Pleguezuelos, Juan M.
name: Vasconcelos, Raquel
Publisher: name: Salvador Milla, Alfredo
Year: 2015
Subjects: subject: Description
subject: Size
subject: Variation
subject: Distribution
subject: Habitat
subject: Abundance
subject: Status
subject: Threats
subject: Diet
subject: Reproduction
subject: FOS: Medical biotechnology
subject: Demography
subject: FOS: Sociology
subject: Interactions
subject: Predators
subject: Parasites
subject: Pathogens
subject: Activity
subject: Home range
subject: Bibliography

description: Reptiles - Orden Squamata - Familia Colubridae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/.
description: A comprehensive review of the natural history of the Algerian False Smooth Snake Macroprotodon cucullatus in Spain.
WG Researcher Engagement: Introducing EOSC (SOA) at the 2nd Austrian Library Congress
Creators: name: Czuray, Marie
name: Flicker, Katharina
name: Saurugger, Bernd
Publisher: name: Zenodo
Year: 2025
Subjects: Library Congress
EOSC
EOSC SOA
Working Group Researcher Engagement

description: The 2nd Austrian Library Congress took place from March 25-28, 2025, at the Austria Center Vienna, focusing on the theme 'Libraries: democratic - diverse - sustainable.' The event covered a wide range of topics, from AI and information literacy to accessibility, participation, sustainability, research data management and Open Science Cooperation. The EOSC SOA Working Group on Researcher Engagement participated in the latter, introducing the EOSC, EOSC SOA and its work. Curious to learn more? View or download the full article.
Design and synthesis of 2-amino-4,6-diarylpyrimidine derivatives as potent α-glucosidase and α-amylase inhibitors: structure–activity relationship, in vitro, QSAR, molecular docking, MD simulations and drug-likeness studies
Creators: name: Mughal, Ehsan Ullah
name: Amjid, Samreen
name: Sadiq, Amina
name: Naeem, Nafeesa
name: Nazir, Yasir
name: Alrafai, H. A.
name: Hassan, Abeer A.
name: Al-Nami, Samar Y.
name: Hafez, Amal A. Abdel
name: Shah, Syed Wadood Ali
name: Ghias, Mehreen
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Space Science
Medicine
Pharmacology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified

description: In the present study, a series of 2-amino-4,6-diarylpyrimidine derivatives was designed, synthesized, characterized and evaluated for their in vitro α-glucosidase and α-amylase enzyme inhibition assays. The outcomes proved that this class of compounds exhibit considerable inhibitory activity against both enzymes. Among the target compounds, compounds 4p and 6p demonstrated the most potent dual inhibition with IC50 = 0.087 ± 0.01 μM for α-glucosidase; 0.189 ± 0.02 μM for α-amylase and IC50 = 0.095 ± 0.03 μM for α-glucosidase; 0.214 ± 0.03 μM for α-amylase, respectively as compared to the standard rutin (IC50 = 0.192 ± 0.02 μM for α-glucosidase and 0.224 ± 0.02 μM for α-amylase). Remarkably, the enzyme inhibition results indicate that test compounds have stronger inhibitory effect on the target enzymes than the positive control, with a significantly lower IC50 value. Moreover, these series of compounds were found to inhibit α-glucosidase activity in a reversible mixed-type manner with IC50 between 0.087 ± 0.01 μM to 1.952 ± 0.26 μM. Furthermore, molecular docking studies were performed to affirm the binding interactions of this scaffold to the active sites of α-glucosidase and α-amylase enzymes. The quantitative structure–activity relationship (QSAR) investigations showed a strong association between 1p–15p structures and their inhibitory actions (IC50) with a correlation value (R2) of 0.999916. Finally, molecular dynamic (MD) simulations were carried out to assess the dynamic behavior, stability of the protein–ligand complex, and binding affinity of the most active inhibitor 4p. The experimental and theoretical results therefore exposed a very good compatibility. Additionally, the drug-likeness assay revealed that some compounds exhibit a linear association with Lipinski’s rule of five, indicating good drug-likeness and bioactivity scores for pharmacological targets. Communicated by Ramaswamy H. Sarma
In vivo and in vitro deformation and strain measurements in human bone and intervertebral disc using MRI based digital volume correlation (DVC)
Creators: name: Tavana, Saman
Publisher: name: Imperial College London
Year: 2021

description: Digital volume correlation (DVC) is emerging as a standard tool for calculating three-dimensional (3D) deformation and strain in biological tissues. To date, DVC has been used extensively in combination with micro computed tomography (micro-CT), synchrotron radiation micro-CT, and clinical CT for strain measurement in trabecular bone, cortical bone, whole bone, and at bone-implant interfaces. However, limited number of studies investigated internal strains within soft biological tissues using CT-based DVC, possibly due to the difficulties of soft tissue visualisation with CT. Additionally, the radiation associated with clinical CT is a limitation that reduces its suitability for use on patients. Using DVC based on MRI may allow non-invasive strain measurements in both soft and hard tissues. The aim of this PhD was to use DVC with MRI for ex vivo strain measurement within human intervertebral disc (IVD) and in vivo strain measurement within human bone and joint. During this PhD, a framework was established to measure strains within human IVDs. Consequently, this technique was used to evaluate the effect of degeneration on the internal strains and the mechanism of failure in human IVDs. Findings identified that degenerate IVDs had higher (p<0.05) axial strains (58% higher), maximum 3D compressive strains (43% higher), and maximum 3D shear strains (41% higher) in comparison to the non-degenerate IVDs, mainly in the lateral and posterior annulus. Subsequently, MRI sequences and DVC settings were optimised to develop a novel clinical MRI-based DVC technique for in vivo deformation and strain measurement in human bone. This technique was implemented to compute in vivo human ankle joint kinematics and tibiotalar joint contact strains. The findings suggested a possible correlation between the sites of peak strains and the location of osteochondral lesions of the talus. In conclusion, DVC was successfully used for ex vivo deformation and strain calculations within human IVDs, and in vivo deformation and strain measurements in human bone and joint. In the future, further development of these techniques may lead to a novel, non-invasive diagnostic tool with the potential to be widely used in clinical settings.
Inelastic dark matter, small scale problems, and the XENON1T excess
Creators: name: Baek, Seungwon
Publisher: name: arXiv
Year: 2021
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We study a generic model in which the dark sector is composed of a Majorana dark matter $χ_1$, its excited state $χ_2$, both at the electroweak scale, and a light dark photon $Z'$ with $m_{Z'} \sim 10^{-4}$ eV. The light $Z'$ enhances the self-scattering elastic cross section $χ_1 χ_1 \to χ_1 χ_1$ enough to solve the small scale problems in the $N$-body simulations with the cold dark matter. The dark matter communicates with the SM via kinetic mixing parameterized by $ε$. The inelastic scattering process $χ_1 χ_1 \to χ_2 χ_2$ followed by the prompt decay $χ_2 \to χ_1 Z'$ generates energetic $Z'$. By setting $δ\equiv m_{χ_2} - m_{χ_1} \simeq 2.8$ keV and $ε\sim 10^{-10}$ the excess in the electron-recoil data at the XENON1T experiment can be explained by the dark-photoelectric effect. The relic abundance of the dark matter can also be accommodated by the thermal freeze-out mechanism via the annihilation $χ_1 χ_1 (χ_2 χ_2) \to Z' Z'$ with the dark gauge coupling constant $α_X \sim 10^{-3}$.
description: 13 pages, 1 figure
Ranita de San Antonio – Hyla molleri Bedriaga, 1889
Creators: name: Ortiz-Santaliestra, Manuel E.
Publisher: name: Salvador Milla, Alfredo
Year: 2015
Subjects: subject: Description
subject: Size
subject: Variation
subject: Distribution
subject: Habitat
subject: Abundance
subject: Status
subject: Threats
subject: Diet
subject: Reproduction
subject: FOS: Medical biotechnology
subject: Demography
subject: FOS: Sociology
subject: Interactions
subject: Predators
subject: Parasites
subject: Pathogens
subject: Activity
subject: Home range
subject: Bibliography

description: Anfibios - Orden Anura - Familia Hylidae en la Enciclopedia Virtual de Vertebrados Españoles, http://www.vertebradosibericos.org/.
description: A comprehensive review of the natural history of the Iberian tree frog Hyla molleri in Spain.
Multiplet supercurrent in Josephson tunneling circuits
Creators: name: Melo, André
name: Fatemi, Valla
name: Akhmerov, Anton R.
Publisher: name: arXiv
Year: 2021
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: The multi-terminal Josephson effect allows DC supercurrent to flow at finite commensurate voltages. Existing proposals to realize this effect rely on nonlocal Andreev processes in superconductor-normal-superconductor junctions. However, this approach requires precise control over microscopic states and is obscured by dissipative current. We show that standard tunnel Josephson circuits also support multiplet supercurrent mediated only by local tunneling processes. Furtheremore, we observe that the supercurrents persist even in the high charging energy regime in which only sequential Cooper transfers are allowed. Finally, we demonstrate that the multiplet supercurrent in these circuits has a quantum geometric component that is distinguinshable from the well-known adiabatic contribution.
Studies on inter-species expression of photosynthesis genes in Rhodobacter capsulatus
Creators: name: Zilsel, Joanna
Publisher: name: University of British Columbia
Year: 2010

description: The primary amino acid sequences of the L, M, and H photosynthetic reaction center peptide subunits from a number of purple non-sulfur bacteria, including Rhodopseudomonas viridis, Rhodobacter sphaeroides, and Rhodobacter capsulatus have been previously shown to be highly homologous, and detailed X-ray crystallographic analyses of reaction centers from two species of purple non-sulfur bacteria, Rps. viridis and R. sphaeroides have shown that all recognized structural and functional features are conserved. Experiments were undertaken to determine whether genes encoding reaction center and light harvesting peptide subunits from one species could be functionally expressed in other species. Plasmid-borne copies of R sphaeroides and Rps. viridis pigment binding-peptide genes were independently introduced into a photosynthetically incompetent R. capsulatus mutant host strain, deficient in all known pigment-binding peptide genes. The R. sphaeroides puf operon, which encodes the L and M subunits of the reaction center as well as both peptide subunits of light harvesting complex I, was shown to be capable of complementing the mutant R. capsulatus host. Hybrid reaction centers, comprised of R. sphaeroides-encoded L and M subunits and an R. capsulatus-encoded H subunit, were formed in addition to the R. sphaeroides-encoded LHI complexes. These hybrid cells were capable of photosynthetic growth, but their slower growth rates under low light conditions and their higher fluorescence emission levels relative to cells containing native complexes, indicated an impairment in energy transduction. The Rps. viridis puf operon was found to be incapable of functional expression in the R. capsulatus mutant host. Introduction of a plasmid-borne copy of the Rps. viridis puhA gene, which encodes the H subunit of the reaction center, into host cells already containing the Rps. viridis puf operon, such that all structural peptides of the Rps. viridis reaction center were present, still did not permit stable assembly of Rps. viridis photosynthetic complexes. RNA blot analysis demonstrated that the barrier to functional expression was not at the level of transcription. Differences between Rps. viridis and R. sphaeroides that may account for their differing abilities to complement the R. capsulatus mutant host strain are discussed.
Spectral and network methods in the analysis of correlation matrices of stock returns
Creators: name: Heimo, Tapio
name: Saramaki, Jari
name: Onnela, Jukka-Pekka
name: Kaski, Kimmo
Publisher: name: arXiv
Year: 2007
Subjects: subject: Physics and Society (physics.soc-ph)
subject: FOS: Physical sciences

description: Correlation matrices inferred from stock return time series contain information on the behaviour of the market, especially on clusters of highly correlating stocks. Here we study a subset of New York Stock Exchange (NYSE) traded stocks and compare three different methods of analysis: i) spectral analysis, i.e. investigation of the eigenvalue-eigenvector pairs of the correlation matrix, ii) asset trees, obtained by constructing the maximal spanning tree of the correlation matrix, and iii) asset graphs, which are networks in which the strongest correlations are depicted as edges. We illustrate and discuss the localisation of the most significant modes of fluctuation, i.e. eigenvectors corresponding to the largest eigenvalues, on the asset trees and graphs.
description: 6 pages, 2 figures
MOESM7 of Mutation of 4-coumarate: coenzyme A ligase 1 gene affects lignin biosynthesis and increases the cell wall digestibility in maize brown midrib5 mutants
Creators: name: Xiong, Wangdan
name: Wu, Zhenying
name: Liu, Yuchen
name: Li, Yu
name: Su, Kunlong
name: Bai, Zetao
name: Guo, Siyi
name: Hu, Zhubing
name: Zhang, Zhiming
name: Bao, Yan
name: Sun, Juan
name: Yang, Guofeng
name: Fu, Chunxiang
Publisher: name: figshare
Year: 2019
Subjects: subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Plant Biology

description: Additional file 7: Table S4. Expression levels of Zm4CL genes in maize different tissues.
Computer aided therapeutic tripeptide design, in alleviating the pathogenic proclivities of nocuous α-synuclein fibrils
Creators: name: Chandrasekhar, G.
name: Srinivasan, E.
name: Nandhini, S.
name: Pravallika, G.
name: Sanjay, G.
name: Rajasekaran, R.
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biophysics
Biochemistry
Medicine
Neuroscience
Pharmacology
Chemical Sciences not elsewhere classified
Computational Biology

description: Parkinson’s disorder (PD) exacerbates neuronal degeneration of motor nerves, thereby effectuating uncoordinated movements and tremors. Aberrant alpha-synuclein (α-syn) is culpable of triggering PD, wherein cytotoxic amyloid aggregates of α-syn get deposited in motor neurons to instigate neuro-degeneration. Amyloid aggregates, typically rich in beta sheets are cardinal targets to mitigate their neurotoxic effects. In this analysis, owing to their interaction specificity, we formulated an efficacious tripeptide out of the aggregation-prone region of α-syn protein. With the help of a proficient computational pipeline, systematic peptide shortening and an adept molecular simulation platform, we formulated a tripeptide, VAV from α-syn structure based hexapeptide KISVRV. Indeed, the VAV tripeptide was able to effectively mitigate the α-syn amyloid fibrils’ dynamic rate of beta-sheet formation. Additional trajectory analyses of the VAV- α-syn complex indicated that, upon its dynamic interaction, VAV efficiently altered the distinct pathogenic structural dynamics of α-syn, further advocating its potential in alleviating aberrant α-syn’s amyloidogenic proclivities. Consistent findings from various computational analyses have led us to surmise that VAV could potentially re-alter the pathogenic conformational orientation of α-syn, essential to mitigate its cytotoxicity. Hence, VAV tripeptide could be an efficacious therapeutic candidate to efficiently ameliorate aberrant α-syn amyloid mediated neurotoxicity, eventually attenuating the nocuous effects of PD. Communicated by Ramaswamy H. Sarma
Deliverable 3.4 - Prophylactic practices for Mediterranean farmed fish
Creators: name: Padrós, Francesc
name: Fioravanti, Marialetizia
name: Ciulli, Sara
name: Gustinelli, Andrea
name: Zarza, Carlos
name: Acosta, Felix
name: Rigos, George
Publisher: name: Zenodo
Year: 2020

description: Prophylaxis can be defined as all the actions taken to prevent disease and therefore can be considered as a synonym of disease prevention. Biosecurity is also related to disease prevention but mainly consists of actions that minimize the risk of introduction and spreading of an infectious disease in a particular place and also spreading to other places. In aquaculture, therefore, biosecurity should be mainly related to those practices aiming at reducing the risk of specific infectious and parasitic diseases, whereas disease prevention and prophylaxis should be viewed with a wider scope, including measures and actions to reduce the susceptibility to infectious diseases and also non-infectious diseases and factors such as stress or environmental conditions, that are closely related to the emergence and expression of the diseases. Prophylaxis, disease prevention and biosecurity should also be clearly differentiated from disease treatments and disease remediation, although in cases, certain measures and tools are used to prevent and also to treat. Treating European sea bass and gilthead seabream diseases has been already addressed in D3.3 of PerformFISH, i.e. Deliverable 3.3 “Best Therapeutics Practices for Mediterranean Farmed Fish”.
Entangled ripples and twists of light: Radial and azimuthal Laguerre-Gaussian mode entanglement
Creators: name: Valencia, Natalia Herrera
name: Srivastav, Vatshal
name: Leedumrongwatthanakun, Saroch
name: McCutcheon, Will
name: Malik, Mehul
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: It is well known that photons can carry a spatial structure akin to a "twisted" or "rippled" wavefront. Such structured light fields have sparked significant interest in both classical and quantum physics, with applications ranging from dense communications to light-matter interaction. Harnessing the full advantage of transverse spatial photonic encoding using the Laguerre-Gaussian (LG) basis in the quantum domain requires control over both the azimuthal (twisted) and radial (rippled) components of photons. However, precise measurement of the radial photonic degree-of-freedom has proven to be experimentally challenging primarily due to its transverse amplitude structure. Here we demonstrate the generation and certification of full-field Laguerre-Gaussian entanglement between photons pairs generated by spontaneous parametric down-conversion in the telecom regime. By precisely tuning the optical system parameters for state generation and collection, and adopting recently developed techniques for precise spatial mode measurement, we are able to certify fidelities up to 85% and entanglement dimensionalities up to 26 in a 43-dimensional radial and azimuthal LG mode space. Furthermore, we study two-photon quantum correlations between 9 LG mode groups, demonstrating a correlation structure related to mode group order and inter-modal cross-talk. In addition, we show how the noise-robustness of high-dimensional entanglement certification can be significantly increased by using measurements in multiple LG mutually unbiased bases. Our work demonstrates the potential offered by the full spatial structure of the two-photon field for enhancing technologies for quantum information processing and communication.
2D-QSAR, molecular docking and MD simulation based virtual screening of the herbal molecules against Alzheimer’s disorder: an approach to predict CNS activity
Creators: name: Thakur, Aman
name: Sharma, Bhanu
name: Parashar, Arun
name: Sharma, Vivek
name: Kumar, Ajay
name: Mehta, Vineet
Publisher: name: Taylor & Francis
Year: 2023
Subjects: subject: Biochemistry
subject: Cell Biology
subject: Neuroscience
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Immunology
subject: FOS: Clinical medicine
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified

description: Acetylcholinesterase (AChE) is one of the key enzyme targets that have been used clinically for the management of Alzheimer’s Disorder (AD). Numerous reports in the literature predict and demonstrate in-vitro, and in-silico anticholinergic activity of herbal molecules, however, majority of them failed to find clinical application. To address these issues, we developed a 2D-QSAR model that could efficiently predict the AChE inhibitory activity of herbal molecules along with predicting their potential to cross the blood-brain-barrier (BBB) to exert their beneficial effects during AD. Virtual screening of the herbal molecules was performed and amentoflavone, asiaticoside, astaxanthin, bahouside, biapigenin, glycyrrhizin, hyperforin, hypericin, and tocopherol were predicted as the most promising herbal molecules for inhibiting AChE. Results were validated through molecular docking, atomistic molecular dynamics simulations and Molecular mechanics-Poisson Boltzmann surface area (MM-PBSA) studies against human AChE (PDB ID: 4EY7). To determine whether or not these molecules can cross BBB to inhibit AChE within the central nervous system (CNS) for being beneficial for the management of AD, we determined a CNS Multi-parameter Optimization (MPO) score, which was found in the range of 1 to 3.76. Overall, the best results were observed for amentoflavone and our results demonstrated a PIC50 value of 7.377 nM, molecular docking score of −11.5 kcal/mol, and CNS MPO score of 3.76. In conclusion, we successfully developed a reliable and efficient 2D-QSAR model and predicted amentoflavone to be the most promising molecule that could inhibit human AChE enzyme within the CNS and could prove beneficial for the management of AD. Communicated by Ramaswamy H. Sarma
On Fox and augmentation quotients of semidirect products
Creators: name: Hartl, Manfred
Publisher: name: arXiv
Year: 2007
Subjects: subject: Group Theory (math.GR)
subject: Rings and Algebras (math.RA)
subject: FOS: Mathematics
subject: 20C07 (Primary) 20J05, 17B35 (Secondary)

description: Let $G$ be a group which is the semidirect product of a normal subgroup $N$ and some subgroup $T$. Let $I^n(G)$, $n\ge 1$, denote the powers of the augmentation ideal $I(G)$ of the group ring $\Z(G)$. Using homological methods the groups $Q_n(G,H) = I^{n-1}(G)I(H)/I^{n}(G)I(H)$, $H=G,N,T$, are functorially expressed in terms of enveloping algebras of certain Lie rings associated with $N$ and $T$, in the following cases: for $n\le 4$ and arbitrary $G,N,T$ (except from one direct summand of $Q_4(G,N)$), and for all $n\ge 2$ if certain filtration quotients of $N$ and $T$ are torsionfree.
description: 39 pages; paper thoroughly revised: notation and presentation improved, many details and new result added (Theorem 1.7)
Narrow escape problem in two-shell spherical domains
Creators: name: Mangeat, Matthieu
name: Rieger, Heiko
Publisher: name: arXiv
Year: 2021
Subjects: subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Intracellular transport in living cells is often spatially inhomogeneous with an accelerated effective diffusion close to the cell membrane and a ballistic motion away from the centrosome due to active transport along actin filaments and microtubules, respectively. Recently it was reported that the mean first passage time (MFPT) for transport to a specific area on the cell membrane is minimal for an optimal actin cortex width. In this paper we ask whether this optimization in a two-compartment domain can also be achieved by passive Brownian particles. We consider a Brownian motion with different diffusion constants in the two shells and a potential barrier between the two and investigate the narrow escape problem by calculating the MFPT for Brownian particles to reach a small window on the external boundary. In two and three dimensions, we derive asymptotic expressions for the MFPT in the thin cortex and small escape region limits confirmed by numerical calculations of the MFPT using the finite element method and stochastic simulations. From this analytical and numeric analysis we finally extract the dependence of the MFPT on the ratio of diffusion constants, the potential barrier height and the width of the outer shell. The first two are monotonous whereas the last one may have a minimum for a sufficiently attractive cortex, for which we propose an analytical expression of the potential barrier height matching very well the numerical predictions.
description: 36 pages, 14 figures (v2)
Accelerating universe in scalar tensor models - confrontation of theoretical predictions with observations
Creators: name: Demianski, M.
name: Piedipalumbo, E.
name: Rubano, C.
name: Tortora, C.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Astrophysics (astro-ph)
subject: FOS: Physical sciences

description: We consider scalar tensor theories of gravity assuming that the scalar field is non minimally coupled with gravity. We use this theory to study evolution of a flat homogeneous and isotropic universe. In this case the dynamical equations can be derived form a point like Lagrangian. We study the general properties of dynamics of this system and show that for a wide range of initial conditions such models lead in a natural way to an accelerated phase of expansion of the universe. Assuming that the point like Lagrangian admits a Noether symmetry we are able to explicitly solve the dynamical equations. We study one particular model and show that its predictions are compatible with observational data, namely the publicly available data on type Ia supernovae, the parameters of large scale structure determined by the 2-degree Field Galaxy Redshift Survey (2dFGRS), the measurements of cosmological distances with the Sunyaev-Zel'dovich effect and the rate of growth of density perturbations}{It turns out that this model have a very interesting feature of producing in a natural way an epoch of accelerated expansion. With an appropriate choice of parameters our model is fully compatible with several observed characteristics of the universe
description: accepted for publication in A&A. arXiv admin note: text overlap with arXiv:astro-ph/0504591 by other authors
Most Efficient Sensor Network Protocol for a Permanent Natural Disaster Monitoring System
Creators: name: Lee, Changmin
name: Kim, Seong-Lyun
Publisher: name: arXiv
Year: 2021
Subjects: subject: Networking and Internet Architecture (cs.NI)
subject: FOS: Computer and information sciences

description: To minimize enormous havoc from disasters, permanent environment monitoring is necessarily required. Thus we propose a novel energy management protocol for energy harvesting wireless sensor networks (EH-WSNs), named the adaptive sensor node management protocol (ASMP). The proposed protocol makes system components to systematically control their performance to conserve the energy. Through this protocol, sensor nodes autonomously activate an additional energy conservation algorithm. ASMP embeds three sampling algorithms. For the optimized environment sampling, we proposed the adaptive sampling algorithm for monitoring (ASA-m). ASA-m estimates the expected time period to occur meaningful change. The meaningful change refers to the distance between two target data for the monitoring QoS. Therefore, ASA-m merely gathers the data the system demands. The continuous adaptive sampling algorithm (CASA) solves the problem to be continuously decreasing energy despite of ASA-m. When the monitored environment shows a linear trend property, the sensor node in CASA rests a sampling process, and the server generates predicted data at the estimated time slot. For guaranteeing the self-sustainability, ASMP uses the recoverable adaptive sampling algorithm (RASA). RASA makes consumed energy smaller than harvested energy by utilizing the predicted data. RASA recharges the energy of the sensor node. Through this method, ASMP achieves both energy conservation and service quality.
Schwarzian Derivative Criteria for Valence of Analytic and Harmonic Mappings
Creators: name: Chuaqui, M.
name: Duren, P.
name: Osgood, B.
Publisher: name: arXiv
Year: 2006
Subjects: subject: Complex Variables (math.CV)
subject: Differential Geometry (math.DG)
subject: FOS: Mathematics
subject: 30C99; 31A05; 53A10

description: For analytic functions in the unit disk, general bounds on the Schwarzian derivative in terms of Nehari functions are shown to imply uniform local univalence and in some cases finite and bounded valence. Similar results are obtained for the Weierstrass--Enneper lifts of planar harmonic mappings to their associated minimal surfaces. Finally certain classes of harmonic mappings are shown to have finite Schwarzian norm.
Off-Diagonal Long-Range Order Implies Vanishing Charge Gap
Creators: name: Tasaki, Hal
name: Watanabe, Haruki
Publisher: name: arXiv
Year: 2021
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: Superconductivity (cond-mat.supr-con)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: For a large class of quantum many-body systems with U(1) symmetry, we prove a general inequality that relates the (off-diagonal) long-range order with the charge gap. For a system of bosons or fermions on a lattice or in the continuum, the inequality implies that a ground state with off-diagonal long-range order inevitably has a vanishing charge gap, and hence is characterized by nonzero charge susceptibility. For a quantum spin system, the inequality implies that a ground state within a magnetization plateau cannot have transverse long-range order.
description: 10 pages, no figures. Minor imporvments in versions 2 and 3. There is a 16 minutes video in which the main results of the paper are described. See https://youtu.be/fvZdgV8Ik-8
ON-MERRIT – Introducing a new project to study inequalities in Open Science and RRI transition
Creators: name: Ross-Hellauer, Tony
name: Reichmann, Stefan
name: Knoth, Petr
name: Schmidt, Birgit
name: Wieser, Bernhard
name: Rodrigues, Eloy
Publisher: name: Zenodo
Year: 2019
Subjects: open science

description: ON-MERRIT (Observing and Negating Matthew Effects in Responsible Research and Innovation Transition) is a new 30 month EC-funded project, starting in October 2019, to study "Matthew effects" of cumulative advantage in Open Science and Responsible Research and Innovation across research, industry and policy making, through a mix of sociological, bibliometric and computational approaches. This poster gives an overview of the project's aims and activities.
Markov type of Alexandrov spaces of nonnegative curvature
Creators: name: Ohta, Shin-ichi
Publisher: name: arXiv
Year: 2007
Subjects: subject: Metric Geometry (math.MG)
subject: Functional Analysis (math.FA)
subject: FOS: Mathematics
subject: 46B20, 53C21, 60J10

description: We prove that Alexandrov spaces $X$ of nonnegative curvature have Markov type 2 in the sense of Ball. As a corollary, any Lipschitz continuous map from a subset of $X$ into a 2-uniformly convex Banach space is extended as a Lipschitz continuous map on the entire space $X$.
description: 13 pages; v2: minor changes
New sulfa drug derivatives and their zinc(II) complexes: synthesis, spectroscopic properties and in vitro cytotoxic activities
Creators: name: Şahal, Hakan
name: Öz, Samet
name: Keskin, Tuba
name: Tekin, Suat
name: Canpolat, Erdal
name: Kaya, Mehmet
Publisher: name: Taylor & Francis
Year: 2023
Subjects: Biochemistry
Cell Biology
Pharmacology
Biotechnology
Chemical Sciences not elsewhere classified
Cancer

description: Synthesis of four sulfa drug derivatives (L1–L4) and Zn(II) complexes derived from sulfonamide group antibiotic substances was carried out using the hydrothermal technique (HT) and their structures of the obtained compounds were explained using elemental analysis (EA), FT-IR and NMR (1H- and 13C-). Cytotoxic activities of four novel sulfa drug based-Schiff base compounds and their Zn(II) complexes were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay using MCF-7 (human breast cancer), Caco-2 (human colorectal adenocarcinoma), A2780 (human ovarian cancer) and LNCaP (human prostate adenocarcinoma) cell lines. LogIC50 values of all obtained compounds were computed with the Graphpad Prism 6 program after 24 h of treatment for MCF-7, Caco-2, A2780 and LNCaP cells. Comet assay experiments were performed using LogIC50 concentrations of all compounds to determine DNA damage. Based on the data obtained, all compounds significantly decreased MCF-7, Caco-2, A2780 and LNCaP cell viability compared to the control groups (p < 0.05). Communicated by Ramaswamy H. Sarma
Accident Tracking and Visual Sharing Using RFID and SDN
Creators: name: Gopi, Alpana
name: R, Divya P
name: Rajan, Litty
name: Rajan, Surya
name: Renjith, Shini
Publisher: name: figshare
Year: 2021
Subjects: Applied Computer Science

description: In this era, many situations request tracking systems. GPS can be used for location tracking, but it has some limitations. By analyzing the problems of using GPS for location tracking, RFID technology integrated with SDN for vehicle tracking has put forward in this paper. In case of road accidents RFID can be used to track the vehicle thereby the authority get information about the vehicle and its owner. With the help of SDN visual sharing is also possible which is useful in case of getting accident claims. This system overcomes the limitations of vehicle tracking using GPS. The main goal of this paper is complete solution architecture for locating, tracking and informing the authority in the right time when accidents are detected.
Allee effect in models of interacting species
Creators: name: Kuperman, Marcelo N
name: Abramson, Guillermo
Publisher: name: arXiv
Year: 2021
Subjects: subject: Populations and Evolution (q-bio.PE)
subject: Biological Physics (physics.bio-ph)
subject: FOS: Biological sciences
subject: FOS: Physical sciences

description: The search for more realistic models for interacting species has produced many adaptations of the original Lotka-Volterra equations, such as the inclusion of the Allee effect and the different Holling's types of functional response. In the present work we show that a correct implementation of both ideas together requires a careful formulation. We focus our work in the fact that a density dependent carrying capacity, combined with the Allee effect, can lead to meaningless effects. We illustrate the difficulties in predator-prey and two-species competition models, together with our proposed solution of the careful inclusion of the corresponding cubic terms.
MOESM5 of Mutation of 4-coumarate: coenzyme A ligase 1 gene affects lignin biosynthesis and increases the cell wall digestibility in maize brown midrib5 mutants
Creators: name: Xiong, Wangdan
name: Wu, Zhenying
name: Liu, Yuchen
name: Li, Yu
name: Su, Kunlong
name: Bai, Zetao
name: Guo, Siyi
name: Hu, Zhubing
name: Zhang, Zhiming
name: Bao, Yan
name: Sun, Juan
name: Yang, Guofeng
name: Fu, Chunxiang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Medicine
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Cancer
subject: Plant Biology

description: Additional file 5: Fig. S2. The 4CL activity of soluble protein extracts containing Zm4CL1 and the truncated Zm4CL1 mutants.
Coupling atomistic models with continuous finite beam elements [Abstract]
Creators: name: Niederhöfer, Florian
name: Wackerfuß, Jens
Publisher: name: Universität Kassel
Year: 2016
Subjects: subject: 620
subject: Diskretes Modell
subject: Simulation
subject: Träger
subject: Baustatik
subject: Finite-Elemente-Methode

description: Abstract
Visually grounded models of spoken language: A survey of datasets, architectures and evaluation techniques
Creators: name: Chrupała, Grzegorz
Publisher: name: arXiv
Year: 2021
Subjects: subject: Artificial Intelligence (cs.AI)
subject: Computation and Language (cs.CL)
subject: Machine Learning (cs.LG)
subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: This survey provides an overview of the evolution of visually grounded models of spoken language over the last 20 years. Such models are inspired by the observation that when children pick up a language, they rely on a wide range of indirect and noisy clues, crucially including signals from the visual modality co-occurring with spoken utterances. Several fields have made important contributions to this approach to modeling or mimicking the process of learning language: Machine Learning, Natural Language and Speech Processing, Computer Vision and Cognitive Science. The current paper brings together these contributions in order to provide a useful introduction and overview for practitioners in all these areas. We discuss the central research questions addressed, the timeline of developments, and the datasets which enabled much of this work. We then summarize the main modeling architectures and offer an exhaustive overview of the evaluation metrics and analysis techniques.
Accident Tracking and Visual Sharing Using RFID and SDN
Creators: name: Gopi, Alpana
name: R, Divya P
name: Rajan, Litty
name: Rajan, Surya
name: Renjith, Shini
Publisher: name: figshare
Year: 2016
Subjects: Applied Computer Science

description: In this era, many situations request tracking systems. GPS can be used for location tracking, but it has some limitations. By analyzing the problems of using GPS for location tracking, RFID technology integrated with SDN for vehicle tracking has put forward in this paper. In case of road accidents RFID can be used to track the vehicle thereby the authority get information about the vehicle and its owner. With the help of SDN visual sharing is also possible which is useful in case of getting accident claims. This system overcomes the limitations of vehicle tracking using GPS. The main goal of this paper is complete solution architecture for locating, tracking and informing the authority in the right time when accidents are detected.