cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Automated program repair: a perspective from metamorphic testing
Creators: name: Jiang, Mingyue
Publisher: name: Swinburne
Year: 2024

description: Test suite based automated program repair aims to automatically fix program bugs. This thesis applies metamorphic testing concepts to address three challenging problems in test suite based automated program repair, including the alleviation of the test oracle problem, the generation of effective input test suites, and the development of an innovative repair method. The application of the proposed approaches has been demonstrated to be able to extend the scope of applicability for test suite based automated program repair and improve its repair effectiveness, which thus increases the practical benefits of automated program repair techniques in assuring software quality.
Surface processing of Additively Manufactured articles for the improvement of antimicrobial properties
Creators: name: Rybalcenko, Konstantin
name: Folgar, Christian
name: Anastasopoulos, Ioannis
name: Ioannides, Giorgio
name: Folgar, Luis
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: Antimicrobial study was conducted to test the surfaces of additively manufactured (AM) polyamide parts via powder-bed fusion. As printed parts exhibit rough, porous and powdery surfaces providing a favorable breeding ground for bacteria and fungi. This creates an issue for AM parts intended for use in medical and other highly controlled applications. A novel surface processing method able to seal and smooth surfaces was used to improve antimicrobial properties of parts. Processed parts were tested for microbial growth and the results were compared to the unprocessed parts. This study presents the obtained results and discusses possible applications of this method.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
L'ébranlement de l'écrit mouvement de l'existence, littérature et geste politique dans la philosophie de Jan Patocka
Creators: name: Parrot, Martin
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Political Science, General.

description: Cette thèse se veut une recherche exégétique au sein de l'oeuvre tardive du philosophe et dissident tchèque Jan Patocka (1907-1977). Elle vise l'illustration et l'analyse de deux articulations précises de sa pensée: (1) les fortes analogies entre, d'un côté, sa définition d'un rapport au monde authentique lors de l'élaboration de sa phénoménologie et de ses travaux sur le platonisme, et de l'autre, sa définition de l'acte d'écriture littéraire; (2) puis, le statut et la signification du politique dans l'élaboration de son questionnement philosophique ainsi que ses incursions dans la philosophie de la littérature. Afin de rigoureusement traiter cette double question sur un terrain encore rarement exploré de l'oeuvre de l'auteur, trois concepts seront examinés et leurs proximités définies: le mouvement de percée, l'acte littéraire, et le politico-moral.
Strategies to evaluate alginate based bioinks applying extrusion printing for biofabrication
Creators: name: Karakya, Emine
name: Fischer, Lena
name: Hazur, Jonas
name: Boccaccini, Aldo R.
name: Thievessen, Ingo
name: Detsch, Rainer
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: For bioprinting, tailored bioinks combining tissue-like mechanical properties, printability and high biocompatibility are needed. The strategy of this project includes the precise characterization of the synthesis route and material properties, description of the printing process, as well as computing of flow and shear stress profile inside the printing needle. Furthermore, in vitro analyses using lentiviral fluorescent reporter cells were performed, which is a novel method that has so far hardly been used in biofabrication. The evaluation of the hydrogel and printing process for successful biofabrication is a multi-stage process and in our case demonstrated that ADA-GEL is a promising bioink.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
title: La reexcavación de la basílica visigoda de Segobriga (Cabeza de Griego, Saelices) : análisis arqueológico, fases constructivas y cronología.
Creators: name: Cebrián Fernández, Rosario
name: Hortelano Uceda, Ignacio
Publisher: name: Deutsches Archäologisches Institut
Year: 2015
Subjects: Segobriga (Saelices, Cuenca)
Cabeza de Griego
westgotische Basilika
christliches suburbium
Segobriga
visigothic Basilica
Christian suburb

description: Madrider Mitteilungen, 56 (2015)
description: Der Beitrag präsentiert die Ergebnisse einer erneuten Ausgrabung der sog. westgotischen Basilika von Segobriga (Cabeza de Griego, Saelices), die im Jahre 2006 durchgeführt wurde. Er bietet eine Beschreibung der erhaltenen Strukturen und entwickelt auf die
description: In this article we present the results of the re-excavation of the so-called Visigothic Basilica in Cabeza de Griego (Segobriga, Saelices) that was carried out in 2006. Conserved structures are described and their dating is established, presenting also a
description: En este artículo se presentan los resultados de la reexcavación de la denominada basílica visigoda de Cabeza de Griego (Segobriga, Saelices) obtenidos en la campaña de excavaciones del año 2006. Se describen las estructuras conservadas y se establece su d
Dmc1-mediated Break-Induced Replication and Mismatch Repair in Meiotic Saccharomyces Cerevisiae
Creators: name: Xue, Lingyan
Publisher: name: Brandeis University
Year: 2022
Subjects: Dmc1
Homologous recombination
Meiosis
Msh2
break-induced replication
DNA Repair

description: During the repair of a double-stranded chromosome break (DSB), an essential step of homologous recombination is searching for homologous DNA sequences and invading the target to repair the break. In somatic (mitotic) cells, this process is performed by the Rad51 recombinase. In meiosis, recombination depends on a meiosis-specific recombinase Dmc1, but still using Rad51 as an accessory factor. Properties of the recombinases have been characterized in vitro, but their cellular strategies working along with relevant mismatch repair proteins remained unexplored in meiosis. In budding yeast, we compared break-induced replication (BIR) events in both a mitotic and meiotic context, in which a site-specific DSB was created by the HO endonuclease. The invading strand and its donor template share a 108 bp region of homology. We used a series of strains in which the donor carries increasing densities of evenly spaced mismatches. We found that the divergent donor substrates diminished BIR events two times faster in meiosis mediated by Dmc1 comparing to the same events in Rad51-mediated diploid and haploid mitosis. This result differs from in vitro studies that had suggested that Dmc1 had a higher tolerance for mismatches than Rad51. In the absence of Dmc1 and without the meiosis-specific Rad51 inhibitor Hed1, Rad51 was able to carry out ectopic recombination with mismatch tolerance and assimilation similar to the mitotic level. I also examined the assimilation of mismatches into the BIR repair product. Nearly all mismatch correction in meiosis depends on the proofreading activity of DNA polymerase Polδ and is independent of Msh2. However, homozygous knockout of the mismatch repair protein Msh2 in strains with mismatches elevated the repair rate by nine-fold, but the trend of mismatch correction is the almost same as the wild type. There is no such suppression of recombination of mismatched substrates when Msh2 is deleted in mitotic cells. Collectively, we concluded that both Dmc1 and Msh2 are factors that uniquely shape the recombination patterns in meiosis. Given the high tolerance of Dmc1 validated in vitro is true, we hypothesized that Msh2 might promote heteroduplex rejection during meiosis to counterbalance the higher mismatch tolerance of Dmc1 when forming the D-loop.
Active Fréedericks Transition in Three-Dimensional Active Nematics
Creators: name: Alam, Salman
Publisher: name: Brandeis University
Year: 2023
Subjects: Active Fréedericks Transition
Active Liquid Crystal
Biological Active Matter
confined active matter
Quantitative Biology
Spontaneous flow transition

description: In the passive Fréedericksz transition, liquid crystal molecules initially aligned along cell boundaries reorient when an external electric or magnetic field surpasses a certain threshold, aligning with the field direction. The impact of the passive Fréedericksz transition was transformative for the field of liquid crystals. It enabled the control of electro-optic switching that led to modern LCD technology.
description: The active Fréedericksz transition, analogous to its passive counterpart, serves as a pivotal focus in understanding the intricate dynamics in the confined 3D active nematics. In contrast to the passive variation dependent on external fields, the active transition is governed by an internally generated active stress, driving a transformation from uniform alignment to non-uniform patterns accompanied by inherent flow. This phenomenon depends on the interplay between nematic elasticity, active stress, and the confining geometry.
description: Our approach involves a strategic design employing composite materials, by dispersing active Microtubules in a dense 3D colloidal fd virus in nematic liquid crystal phase, decoupling active and passive stresses. This unique framework provides an avenue for delving into the active Fréedericksz transition's depths. Through NADH/ATPase assays, we not only affirm that active stress remains unaffected by fd virus concentration or nematic elasticity, but we also demonstrate that the stable states indeed exhibit activity, as motors actively consume ATP on a microscopic scale and are collectively generating active stresses at the mesoscopic scale.
description: Further, we introduce a related variant of the active Fréedericksz transition that holds promise for measuring active stress. This involves stabilizing the active nematic within a channel geometry using a strong external magnetic field. Additionally, we explore an alternative active liquid crystal configuration, utilizing longer salmonella flagella ($3-6\mu m$) compared to fd virus (800nM). This approach enhances nematic alignment and elasticity, facilitating the observation of flow transitions at a larger, more manageable scale.
description: This alternative setup yields distinct behaviors: under conditions of high active stress and large confinement, we observe homogenous turbulent states. Conversely, with lower active stress or smaller confinement settings, we witness the intriguing phase separation of active microtubule bundles within the uniform flagella background. This phase separation is not understood and requires further investigation.
Comparing Technologies of Additive Manufacturing for the Development of Modular Dosimetry Phantoms in Radiation Therapy
Creators: name: Wegner, Marie
name: Spallek, Johanna
name: Krause, Dieter
name: Gargioni, Elisabetta
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: In radiotherapy, X-ray imaging and dose quality assurance is often carried out using physical phantoms, which simulate the X-ray attenuation of biological tissue. Additive manufacturing (AM) allows to produce cost-effective phantoms that can easily be adapted to different purposes. The aim of this work was to compare mechanical and X-ray attenuation properties of different materials, used in different AM technologies, machines, and materials. The average Hounsfield Units (HU) were measured by means of computed tomography (CT). The materials displayed tissue-equivalent CT numbers ranging from -104 HU to 1627 HU, showing a broad field of application for phantoms in radiotherapy.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
title: ÐÐ¾Ð¼Ð¿Ð°ÐºÑÐ½Ð¾Ðµ Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ½Ð¾Ðµ ÑÐ´ÑÐ¾ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð´ÐµÐºÐ¾Ð´ÐµÑÐ° Ð¿Ð¾Ð»ÑÑÐ½ÑÑ ÐºÐ¾Ð´Ð¾Ð² Ð´Ð»Ñ Ð¼Ð¾Ð±Ð¸Ð»ÑÐ½ÑÑ ÑÐµÑÐ¼Ð¸Ð½Ð°Ð»Ð¾Ð² 5G
title: Ð²ÑÐ¿ÑÑÐºÐ½Ð°Ñ ÐºÐ²Ð°Ð»Ð¸ÑÐ¸ÐºÐ°ÑÐ¸Ð¾Ð½Ð½Ð°Ñ ÑÐ°Ð±Ð¾ÑÐ° Ð¼Ð°Ð³Ð¸ÑÑÑÐ°
titleType: Subtitle
title: Low-complex polar codes hardware sequential decoding core for 5G mobile terminals
Creators: name: ÐÐ¾Ð»Ð¸ÑÑÐº, ÐÐ°Ð½Ð½Ð°
Publisher: name: Ð¡Ð°Ð½ÐºÑ-ÐÐµÑÐµÑÐ±ÑÑÐ³ÑÐºÐ¸Ð¹ Ð¿Ð¾Ð»Ð¸ÑÐµÑÐ½Ð¸ÑÐµÑÐºÐ¸Ð¹ ÑÐ½Ð¸Ð²ÐµÑÑÐ¸ÑÐµÑ ÐÐµÑÑÐ° ÐÐµÐ»Ð¸ÐºÐ¾Ð³Ð¾
Year: 2024
Subjects: Ð¿Ð¾Ð»ÑÑÐ½ÑÐµ ÐºÐ¾Ð´Ñ
Ð´ÐµÐºÐ¾Ð´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ðµ Ð¿Ð¾Ð»ÑÑÐ½ÑÑ ÐºÐ¾Ð´Ð¾Ð²
Ð±Ð»Ð¾ÑÐ½ÑÐ¹ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½ÑÐ¹ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼
Ð²Ð½ÐµÑÐ½Ð¸Ðµ ÐºÐ¾Ð´Ñ
Ð±Ð»Ð¾Ðº ÑÐ°ÑÑÐµÑÐ° Ð¼ÐµÑÑÐ¸Ðº
Ð¿ÑÐ¸Ð¾ÑÐ¸ÑÐµÑÐ½Ð°Ñ Ð¾ÑÐµÑÐµÐ´Ñ
ÐÐÐÐ¡
polar codes
decoding of polar codes
block sequential algorithm
outer codes
score processor
priority queue
FPGA

description: Ð Ð´Ð°Ð½Ð½Ð¾Ð¹ ÑÐ°Ð±Ð¾ÑÐµ Ð±ÑÐ»Ð° ÑÐ°Ð·ÑÐ°Ð±Ð¾ÑÐ°Ð½Ð° Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÐ° ÑÐ´ÑÐ° Ð±Ð»Ð¾ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð´ÐµÐºÐ¾Ð´ÐµÑÐ° Ð¿Ð¾Ð»ÑÑÐ½ÑÑ ÐºÐ¾Ð´Ð¾Ð², Ð´Ð»Ñ ÑÐµÐ°Ð»Ð¸Ð·Ð¾Ð²Ð°Ð½Ð½Ð¾Ð¹ Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÑ Ð±ÑÐ» Ð¿Ð¾Ð»ÑÑÐµÐ½ Ð¾ÑÑÐµÑ Ð¾ ÐºÐ¾Ð»Ð¸ÑÐµÑÑÐ²Ðµ Ð·Ð°ÑÑÐ°ÑÐµÐ½Ð½ÑÑ ÑÐµÑÑÑÑÐ¾Ð². Ð ÐµÐ°Ð»Ð¸Ð·Ð¾Ð²Ð°Ð½Ð½Ð°Ñ Ð°ÑÑÐ¸ÑÐµÐºÑÑÑÐ° Ð±ÑÐ»Ð° Ð²ÐµÑÐ¸ÑÐ¸ÑÐ¸ÑÐ¾Ð²Ð°Ð½Ð° Ð¿ÑÑÐµÐ¼ ÑÑÐ°Ð²Ð½ÐµÐ½Ð¸Ñ Ñ Ð¿ÑÐ¾Ð³ÑÐ°Ð¼Ð¼Ð½Ð¾Ð¹ Ð¼Ð¾Ð´ÐµÐ»ÑÑ Ð´ÐµÐºÐ¾Ð´ÐµÑÐ°. Ð ÑÐµÐ·ÑÐ»ÑÑÐ°ÑÐµ ÑÐ°Ð±Ð¾ÑÑ Ð±ÑÐ»Ð¾ ÑÐµÐ°Ð»Ð¸Ð·Ð¾Ð²Ð°Ð½Ð¾ ÐºÐ¾Ð¼Ð¿Ð°ÐºÑÐ½Ð¾Ðµ ÑÐ´ÑÐ¾ Ð´ÐµÐºÐ¾Ð´ÐµÑÐ° Ð¿Ð¾Ð»ÑÑÐ½ÑÑ ÐºÐ¾Ð´Ð¾Ð² Ð´Ð»Ñ Ð¿ÑÐ¸Ð¼ÐµÐ½ÐµÐ½Ð¸Ñ Ð² Ð½Ð¸ÑÑÐ¾Ð´ÑÑÐ¸Ñ ÐºÐ°Ð½Ð°Ð»Ð°Ñ ÑÑÐ°Ð½Ð´Ð°ÑÑÐ° 5G. ÐÐ¾Ð²Ð¸Ð·Ð½Ð° ÑÐ°Ð±Ð¾ÑÑ Ð¾Ð±ÑÑÐ»Ð¾Ð²Ð»ÐµÐ½Ð° Ð¾ÑÑÑÑÑÑÐ²Ð¸ÐµÐ¼ Ð½Ð°ÑÑÐ½ÑÑ Ð¿ÑÐ±Ð»Ð¸ÐºÐ°ÑÐ¸Ð¹ Ð½Ð° ÑÐµÐ¼Ñ Ð°Ð¿Ð¿Ð°ÑÐ°ÑÐ½Ð¾Ð¹ ÑÐµÐ°Ð»Ð¸Ð·Ð°ÑÐ¸Ð¸ Ð±Ð»Ð¾ÑÐ½Ð¾Ð³Ð¾ Ð¿Ð¾ÑÐ»ÐµÐ´Ð¾Ð²Ð°ÑÐµÐ»ÑÐ½Ð¾Ð³Ð¾ Ð°Ð»Ð³Ð¾ÑÐ¸ÑÐ¼Ð° Ð´ÐµÐºÐ¾Ð´Ð¸ÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ð¾Ð»ÑÑÐ½ÑÑ ÐºÐ¾Ð´Ð¾Ð².
description: In this work the hardware architecture of block sequential decoder of polar codes was developed, and the report on the resource utilization for implemented architecture was received. Implemented architecture was verified by comparing with software model of the decoder. As a result, the low-complex decoder of polar codes for 5G downlink channel was implemented. The novelty of the work is conditioned by absence of scientific publications devoted to hardware implementation of the block sequential decoder.
Overcoming Binarism: New Faces of Solidarity in Israel and Palestine
Creators: name: McCracken-Flesher, Conor Paul
Publisher: name: Brandeis University
Year: 2024
Subjects: activism
migrant
Mizrahi
palestine
queer
Judaic studies
Jewish Studies
Israel

description: Conflict in Israel and Palestine is typically characterized as a binary phenomenon. This paper interrogates this binarism. It recognizes instead that Ashkenazi hegemony operates as a major generative force of oppression and conflict in Israel and Palestine. It considers the multiplicity of populations, whether Israeli, Palestinian, migrant or refugee, and suggests how their common patterns of disenfranchisement and oppression might be leveraged in the cause of conflict resolution. We will explore a structure of dominance that affects multiple non-dominant groups in the region: Palestinians, Mizrahi Jews, migrants, and LGBTQ Israelis and Palestinians. Finally, this approach suggests a way forward: uniting a coalition of these currently disempowered groups, with the aim to transform the conflict by addressing the root cause: the persistent hegemony of one group, Ashkenazim, in political, civic, and social structures.
Design of 3D-printable nasopharyngeal swabs in Matlab for COVID-19 testing
Creators: name: Sun, Yilun
name: Mercader, Alexandra
name: Lueth, Tim C.
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: As an important diagnostic device for detecting respiratory infections, the nasopharyngeal swab is running out of supply due to the fast spread of COVID-19. In this short paper, we present a novel design platform in Matlab for realizing patient-specific nasopharyngeal swabs that can be quickly 3D-printed to fill the swabs’ shortage. Firstly, the swab is realized with our geometry modeling tool using the size derived from the patient’s CT data. Then, Selective-Laser-Sintering (SLS) is employed to print the swab using polyamide as biocompatible material. A printed swab is also presented to demonstrate the performance of the proposed design platform.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Additively manufactured anatomical heart model for performance evaluation of aortic valve implants
Creators: name: Kuhl, Juliane
name: Mendoza Ponce, Pablo Daniel
name: Krautschneider, Wolfgang
name: Krause, Dieter
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: It is suspected that the minimal invasive implantation of aortic valves (TAVI procedure) causes damage to the implant that affects its performance. Medical simulators can be used to investigate this suspicion systematically, repeatedly and under constant conditions. This paper describes the development of a heart model that extends the existing HANNES simulator for aortic valve performance evaluation. The advantages of additive manufacturing (AM) are used to provide an anatomically realistic replication of the relevant anatomical sections of the heart and the aortic root.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Mechanical performances of lightweight structures for orthopaedic implants
Creators: name: Yan, Lina
name: O'Neill, Gavin K.
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: Lightweight structures (LWS) or cellular structures have been widely applied in product designs for the aerospace and biomedical industries. Using the advanced additive manufacturing technology, orthopaedic implants can be designed using LWS to achieve low young’s modulus and good bending stiffness, with additional benefits of cell ingrowth if open lattices were designed. In this study, seven patterns of LWS were printed using selective laser melting method. To evaluate the effective young’s modulus as well as the bending stiffness of those LWS, tensile and four-points bending tests were conducted according to the standards of ASTM E8 and F382.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Photon emissions from ion beam-target gas collisions in a mass spectrometer and the thermochemistry of organic free radicals and cations.
Creators: name: Mayer, Paul Michael.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Chemistry, Physical.

description: This thesis represents the culmination of four years of research into two aspects of gas phase ion chemistry. The first was an attempt to obtain information on internal excitation in polyatomic projectile - target gas collisions in a mass spectrometer. Knowledge of internal excitation is critical to the interpretation of collision induced dissociation (CID) mass spectra. A novel collision cell was designed for a VG ZAB-2F sector mass spectrometer which permitted the detection and analysis of photon emissions from keV projectile - target gas collisions. Early experiments performed in the second field-free region of the mass spectrometer (sec. 4.2) involved the analysis of emitted light with a series of wavelength cutoff filters. Histographic emission spectra were obtained for three $\rm C\sb2,H\sb4,O\sp{+\cdot}$ ions and two $\rm C\sb2,H\sb5,Cl\sp{+\cdot}$ ions. The spectral characteristics were found to be indicative of ion structure. This led to the development of a more elaborate apparatus in the third field-free region of the ZAB which enabled the aquisition of monochromated emission spectra (sec. 4.3). The emission spectra obtained for 8 keV $\rm N\sb2\sp{+\cdot},O\sb2\sp{+\cdot}\ and\ CO\sb2\sp{+\cdot}$ projectile ions with the target gases He, N$\sb2$, O$\sb2$ and CO$\sb2$ showed that (a) collisional excitation of the ions was a vertical process, (b) considerable translational kinetic energy was converted into internal energy in the collisions (up to 22 eV) and (c) the observed emissions relate to the relative geometries of the ground and excited states of the ions. Histographic spectra for these three projectiles obtained with 18 target gasses exhibited definite trends. The abundance of fragment ions in the collision induced dissociation mass spectra of N$\sb2\sp{+\cdot}$ and CO$\sb2\sp{+\cdot}$ was found to increase linearly with emission intensity, indicating that fragmentation was the result of electronic excitation in the ions. A review was made of the degree of charge delocalization in $-$CN substituted radical cations. Semi-empirical calculations showed that the $-$CN group acted primarily as an inductive electrol withdrawing group in radical cations, carrying very little positive charge. The $-$CN group was found to raise the ionic energy of molecules compared to $-$H independent of the nature of the rest of the molecule (containing saturated, double and triple bonds or aromatic ring). The heats of formation of the $-$CN containing radical cations were 43 $\pm$ 3 kcal mol$\sp{-1}$ higher than their $-$H substituted analogues in all cases. These results were consistent with an inductive electron withdrawing cyano group which does not participate in the charge distribution of the ions. (Abstract shortened by UMI.)
3D printing workflows for printing individualized personal protective equipment: an overview
Creators: name: Meglioli, Matteo
name: Toffoli, Andrea
name: Macaluso, Guido Maria
name: Catros, Sylvain
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: Sars-Cov-2 pandemic has taken hold over the globe in the last months. Even the best healthcare systems all over the world are overwhelmed by the number of patients and the lack of personal protective equipment (PPE). Medical operators are exposed at high risk for contracting COVID-19. Additive manufacturing techniques allow to produce protective masks and facial shield. Thanks to 3D scans of the face, open-source files and software, many researchers and clinicians can print individualized PPE. This method paper aims to illustrate the key-aspects for producing individualized protective masks and face shields.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Pulse-Coupled Belousov-Zhabotinsky Oscillators with Activity Dependent Coupling
Creators: name: McAvoy, Malia
Publisher: name: Brandeis University
Year: 2015

description: Central pattern generator (CPG) networks produce characteristic repetitive firing patterns that drive motor motions such as that of the pylorus of the lobster. Maintaining the physiological activity of these networks under various conditions is important. Synaptic plasticity, the tuning of the strengths of synapses, may take place based on the activity of the network. Calculations using a simple model featuring the three main neuron types of the lobster pyloric network CPG have shown that simple activity dependent rules can ensure the physiological activity. The tuning of connection strengths based on the activity of the members in the network is a generic idea that may be tested in other systems as well. In this work we studied tri-membered networks of pulse-coupled Belousov-Zhabotinsky oscillators both in numerical simulations and experiments. We first established the characteristic behaviors of the networks with different topologies. We found that the pyloric network topology is unique because it has a preference for triphasic oscillations in a specific peak order when the coupling strengths are equal and the cycle lengths of the oscillators match. We have found that other behaviors may appear when cycle lengths differ more than 4\\%. After establishing the main characteristics of two tuning mechanisms, we found that a method using a common target activity may be sufficient to secure the preferred triphasic behavior even if the natural activities differ 14\\%. Our findings support that activity dependent modification of interaction strength may ensure the stability of network dynamics in CPGs as well as other systems.
Dimensional consistency of SLM printed orthopaedic implants designed using lightweight structures
Creators: name: Yan, Lina
name: Zhao, Li Ping
name: O'Neill, Gavin Kane
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: To solve the stress shielding problem in the orthopaedic implants applications, lightweight lattice structures were designed to optimize the internal of the implants. The variation of truss size of lattices can affect the mechanical performances of implants. Also the printed dimension of the shell is closely related to the fitting of implants, and its thickness will again affect the mechanical property of the printed implants. In this study, high resolution X-ray computed tomography was used to quantitatively investigate the consistency of the dimensions in the designed and printed orthopaedic implants.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Du soleil de l'Algérie à l'ombre de la censure franquiste: Traduction et retraduction de "L'Étranger" d'Albert Camus
Creators: name: Calixte, Brigitte
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Literature, Latin American.
subject: Literature, Romance.
subject: Literature, African.

description: In a field such as literature, the sense of belonging to a time, a history, a culture, a society or a social class, among other things, inevitably influences the creation of a text---even if it's only done unconsciously. Thus, writing isn't done in a vacuum. By extension, in translation, the context in which the translator exists also tints the text with the reality that the transfer from a source language to a target language is done. Starting with the assumption that the different political, social and cultural contexts surrounding the translation of Albert Camus' L'Etranger influenced the translation and retranslation of the book in Spanish, I will demonstrate and interpret the differences between three Spanish versions of the novel. The first translation was completed in Argentina, in 1949, while Spain was under Franco's dictatorship. Deemed immoral by Franco's regime, its publication was censored in Spain for several years before finally being authorized in 1958---a year after Albert Camus received the Nobel Prize of Literature. A retranslation of the book was completed in 1999 as Spain was marking almost a quarter of a century of democratic rule. More precisely, I will first compare extracts from the first Spanish translation of L'Etranger---done in Argentina by Bonifacio del Carril---with the revised version of that same translation, which was authorized and published in Spain in 1958. My objective for this comparison will be to illustrate the nature of translation by attempting to verify the hypothesis according to which the revised translation of 1958 reflects corrections aimed at actualizing the translation of 1949 in order to more accurately comply with the vocabulary and syntax used in Spain. I will then see how these chosen extracts differ between the first Spanish translation (original version of 1949 and revised version of 1958) and the retranslation done by Jose Angel Valente in 1999, considering that one translation was done during the dictatorship and subject to censorship, while the other was done under a democratic Spain.
Leo Strauss et Max Weber: La critique straussienne du relativisme dogmatique
Creators: name: Boulet, Paul-Émile
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Philosophy.

description: Dans ce mémoire, nous analysons en profondeur le chapitre de Droit naturel et histoire que Strauss consacre au sociologue Max Weber. Nous soutenons que Strauss y critique non pas Weber, mais plutôt le relativisme dogmatique. Nous montrons que selon Strauss, le relativisme dogmatique est un vice intellectuel et moral qu'il faut combattre en raison de son influence néfaste sur la pensée et la société. Après avoir exposé la conception straussienne de la philosophie et de la prudence du philosophe, nous montrons comment Strauss s'oppose au relativisme dogmatique à la fois pour des raisons philosophiques et politiques. D'une part, le relativisme dogmatique est un vice intellectuel qui tend à détourner les hommes de la voie de la philosophie zététique prônée par Strauss. D'autre part, il est un vice moral néfaste pour la société, car en gagnant en influence, il tend à détruire les convictions des citoyens sur la nature du bien.
Addressing Inequities in the Death and Dying Experience through Multidisciplinary Education and Training
Creators: name: Decker, Autumn Elizabeth
Publisher: name: Washington State University
Year: 2024
Subjects: death
dying
prevention science
Education
Gerontology
Social Sciences Education

description: Globally, nationally, regionally, and locally, we are facing a population shift. The number of individuals aged 65 and older will increase exponentially in the coming years, particularly for racially, ethnically, and culturally diverse groups. People are living longer but not necessarily healthier lives. This increase in longevity, coupled with a stagnation in health span, will result in a greater number of those dying, thus increasing pressure on the health and death care systems. To support the health and human service workforce, there is a need for enhanced evidence-based pedagogical interventions aimed at improving death education of these workers. Thus, this dissertation, following an upstream to downstream public health approach, includes three manuscripts that explored death education and end-of-life (EOL) experiences of several groups of people. The primary goals of this 3-manuscript dissertation were to: 1) explore how cultural content, cultural humility, and EOL experiences of diverse groups are integrated in undergraduate thanatology courses, 2) assess the literature related to death and dying coursework in health professional education curriculum, and 3) examine healthcare professionals’ involvement with the EOL experience for diverse groups of people. Together, this dissertation contributes to the state of death education both in undergraduate and health professional education settings and illuminates the influence that health professionals have on the EOL experience of decedents with diverse identities and their place of death.
Nadia Boulanger and "La Ville Morte": En'gendering' a woman's role in the making of an opera
Creators: name: Francis, Kimberly
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2005
Subjects: subject: Music.
subject: Women's Studies.

description: The life of twentieth-century French theorist, conductor, composer, performer and pedagogue Nadia Boulanger has affected North American music substantially, yet there are many questions surrounding her legacy which remain difficult to answer conclusively. Especially convoluted and contentious is the role she played in the making of an opera, based on a libretto by Gabrielle d'Annunzio, entitled La Ville Morte; a project she undertook with her then mentor---pianist and composer Raoul Pugno. This thesis re-writes the genesis of the opera La Ville Morte, drawing from autograph scores, the working libretto, and personal documents housed at the Bibliotheque Nationale in Paris, France. It presents a revisionist image of Nadia Boulanger, with special considerations of the gender discourses which influenced and were manifested in the relations which she had with those around her, including Pugno, and d'Annunzio. This thesis also proposes theories of Boulanger's and Pugno's personal relationship and addresses why Boulanger eventually abandoned composition. Through examination of this evidence, this thesis presents a new, more variegated image of Nadia Boulanger and her role as a composer during the beginning of the twentieth century.
Polydopamine Functionalized 3D Printed Scaffolds for Bone Tissue Engineering
Creators: name: Chakka, Jaidev
name: Laird, Noah
name: Acri, Timothy
name: Elangovan, Satheesh
name: Salem, Aliasger
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: 3D printing offers unique solutions for bone tissue regeneration with an opportunity to engineer scaffolds with the desired structure, shape, and porosity. Scaffold’s surface-to-cell interaction is critical for better tissue integration and regeneration. To achieve this, we have surface modified the 3D printed scaffolds with polydopamine (PDA) to evaluate the potential of the surface modification for bone regeneration.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Exploring realistic haptics for 3D-printed organ phantoms in surgery training in VR and AR
Creators: name: Lück, Thomas
name: Nopper, Hans
name: Schendel, Olav
name: Weyhe, Dirk
name: Salzmann, Daniela
name: Uslar, Verena
name: Reinschluessel, Anke V.
name: Döring, Tanja
name: Muender, Thomas
name: Malaka, Rainer
name: Schenk, Andrea
name: Schumann, Christian
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: Virtual (VR) and Augmented reality (AR) represent excellent tools for surgeons to understand spatial relationships, to train their workflow to improve surgery results. By providing realistic haptic feedback, implementing 3D-printed organ phantoms to those tools, their benefit gets even more compelling, increasing their immersion. In this work investigates the realism of organ phantoms regarding physical hardness, touch and feel. In a user study with 12 surgeons, we evaluated casted liver phantoms in 50 %, scale of the actual liver size. Results from surgeons allowed the configuration of a measurement tool for exact exploration of realistic haptics within this context.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
Ramping-up 3D-printed corona devices – additive manufacturing opposing injection moulding
Creators: name: Lück, Thomas
name: Seifarth, Christian
name: Malauschek, Peter
name: Schendel, Olav
name: Nopper, Hans
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: Additive manufacturing (AM) represents an excellent tool to accelerate the product development process. Used as modern manufacturing technology it still has to compete with traditional technologies like e.g. injection molding. Having both technologies in house available, cirp GmbH faces decision making for the adequate tool within that context at first hand. A good example is the ramped up development of 2 corona devices namely a reusable respirator mask and an aerosol protection face-shield. This work assesses the cost and benefits and the subsequent production decisions using the example of those 2 devices.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
PEGDA drug delivery scaffolds manufactured with a novel hybrid AM process
Creators: name: Rekowska Natalia
name: Grabow, Niels
name: Seitz, Hermann
name: Mau, Robert
name: Reiss, Alexander
name: Konasch, Jan
name: Eickner, Thomas
name: Teske, Michael
Publisher: name: Transactions on Additive Manufacturing Meets Medicine
Year: 2020

description: Additive manufacturing (AM) of drug delivery systems (DDS) is a promising tool for the development of patient-tailored treatments to ensure exact formation of individual scaffolds with specific incorporated drug combinations and concentrations. This study describes a novel hybrid AM process, combining stereolithography and inkjet printing, for printing a basic Polyethylene Glycol Diacrylate (PEGDA) DDS body and placing the model drug acetylsalicylic acid (ASA) in different drug depot locations. Adjusting the drug release by drug depot positioning according to drug diffusion is being investigated. The drug release rates from first 3D printed samples are being shown.
description: Transactions on Additive Manufacturing Meets Medicine, Vol 2 No 1 (2020): Trans. AMMM
The Needs and Experiences of Women with a PALB2 Mutation in the Process of Family Risk Disclosure and Cascade Testing
Creators: name: Echmalian, Corinne
Publisher: name: Brandeis University
Year: 2021
Subjects: family communication
genetic counseling
hereditary cancer
moderate-risk
PALB2
risk disclosure
Medical Counseling

description: Cancer genetic testing is unlike other medical testing because results may guide recommendations not only for the patient, but also their family members. For this reason, it is important to understand how families communicate about hereditary cancer risks and identify areas of need. This study interviewed women with a PALB2 mutation about risk disclosure and cascade testing within their families. We found that our participants generally wanted their relatives to be informed about the PALB2 mutation for the good of their health or because of a sense of obligation. Participants reported factors such as closeness of relation, the age and/or gender of relatives, and difficult emotions influenced their disclosure decisions or experiences. There are both emotional barriers, such as fear and guilt, and logistical barriers, such as physical access and health insurance, to cascade testing for family members. Based on participants’ experiences, we identified areas in which genetic counselors and other healthcare professionals can offer additional support during the family communication process. Many participants found it difficult to identify reliable information to educate themselves and their families about PALB2. Participants also identified support as a necessary resource in the process of risk disclosure. Healthcare professionals should be prepared to provide PALB2-specific informational resources in patient-friendly language, support resources, and family communication resources. Cascade testing is essential to maximize the greatest benefits from genetic testing. As we continue to learn more about health management for individuals with hereditary cancer risks, we must investigate approaches to increasing cascade testing in families.
Epinephrine and glucagon effects on the second messengers cAMP and IP(3) in fish hepatocytes.
Creators: name: Gambarotta, Adriana.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1994
Subjects: subject: Biology, Botany.

description: This thesis demonstrates the production of IP$\sb3$ and confirms the production of cAMP in eel and bullhead hepatocytes following exposure to either, epinephrine (EPI) or glucagon (GLU). These findings indicate the presence of both transduction systems at least in these two fish species. As in mammals, both hormones function by stimulating the production of different amounts of second messengers. In fish hepatocytes the production of these intracellular mediators was significantly less with GLU than with EFI. The activity of the enzyme adenylyl cyclase (ACase) was assessed to correlate the enzyme activities in crude membrane preparations with the production of cAMP in intact cells following EPI and GLU stimulation. Moreover the use of the adrenergic $\alpha$- and $\beta$-antagonists phentolamine and propranolol provided evidence for an effect of EPI on both $\alpha\sb1$- and $\beta\sb2$-adrenoceptors. The presence of the $\alpha\sb1-$subtype was confirmed in black bullhead and assessed for the first time in American eel liver membranes with the specific-binding of radioactive prazosin ($\sp3$H-PRZ), a classical $\alpha\sb1$-antagonist, and the displacement of $\sp3$H-PRZ with other non-radioactive, adrenergic antagonists. The order of potency displayed by these ligands was typical for $\alpha\sb1$-adrenoceptors of mammals. Similar affinity for PRZ was found in the two species, whereas eel showed less receptor density than bullhead membranes. However, the binding capacity was found to be within the range of the mammalian receptors. Moreover the existence of IP$\sb3$-binding sites, that may account for the involvement of a Ca$\sp{2+}$ messenger system in response to EPI and GLU action was assessed for the first time in fish hepatocytes. Eel and bullhead microsomal preparations showed different affinities and binding capacities for IP$\sb3.$ These results give support to the hypothesis that both hormones may induce intracellular Ca$\sp{2+}$ oscillations. (Abstract shortened by UMI.)
A bioinspired interphase for improved carbon-fibre composite performance
Creators: name: Radjef, Racim
Publisher: name: Swinburne
Year: 2024

description: This work focused on the surface properties of carbon-fibres and the effects of different surface treatments on the adhesion behaviour between fibres and matrix. An alternative approach to the current production process of carbon-fibres is presented which uses a dry plasma treatment to achieve comparable results in regards to fibre-matrix adhesion.
Preliminary studies focused on single layer plasma films with controllable mechanical properties to form an interphase between fibres and matrix that combines high strength and energy absorption/damping capabilities. This would increase the service life of carbon-fibre composites by preventing micro-cracks between fibres and matrix.
Cyclic variation in combustion in a constant volume combustion chamber.
Creators: name: Ghorbali, Ali.
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 1993
Subjects: subject: Engineering, Mechanical.

description: Cycle to cycle variations in combustion and turbulence characteristics in a swirling flow were measured in a cylindrical vessel. The vessel was charged by rapid tangential injection using a shrouded valve for two valve lifts (7 mm and 12 mm). A premixed lean mixture of propane and air ($\phi$ = 0.8) was ignited at quarter radius from the center. Pressure rise as a function of time was measured using a pressure transducer. Mean flow, turbulence intensity and Taylor microscale were estimated by statistical analysis of a single hot wire anemometer signal using ensemble averaging and cyclic analysis. Results obtained indicate that changing the valve lift changes turbulence characteristics at mid-radius. However, turbulence characteristics at quarter radius from center and quarter radius to wall were found to be independent of valve lift. Mean time, standard deviation of mean time delay and Taylor microscale were estimated using combustion pressure traces. Results indicate that the mean time and the standard deviation ignition are weak functions of mean flow and turbulence intensity and strong functions of the Taylor microscale as implied by the Tennekes model. Cyclic variations at ignition were observed to contribute the most to cyclic variations.
Leveraging Legacy and Economic Motivations: Increasing Support to Address Climate Change
Creators: name: Rappoport, Isabel
Publisher: name: Brandeis University
Year: 2018
Subjects: Legacy
Behavior Change
Attitude
Motivation
Climate Change

description: The complex long-term nature of climate change often leads people to distance themselves from its impacts. Recent studies suggest that harnessing legacy motivations, or peoples’ interest in their personal legacies and concern for future generations, may be a successful mechanism for overcoming this barrier. It has also been shown that highlighting economic benefits of addressing climate change may motivate certain individuals. The present study extended previous research by examining how legacy and economic motivations can be leveraged to overcome this barrier and increase attitudinal and behavioral support to address climate change, and determine which demographic groups respond to each motivation. Using a between-subjects posttest only design, 422 adults recruited through Amazon’s MTurk were randomly assigned to a legacy, economic or control motivation condition containing information about climate change. Contrary to prediction the findings revealed no significant main effect of motivation condition on our behavioral intention and attitude questionnaire measures. Per our prediction there was a significant interaction effect of gender by motivation, indicating women expressed more positive intentions in the legacy condition than men; however, this was also true in the economic condition. Contrary to prediction, parents indicated more positive intentions in the economic condition, and non-parents were more motivated by the legacy condition. Additionally, participants with college or more education expressed more positive attitudes towards climate change in the legacy motivation than those in the control. No other significant interaction effects were found for the other demographic groups by condition (political affiliation and income), and small sample size issues prevented certain analyses. These findings add to on-going research informing education and communication efforts on climate change, and future research should continue to investigate how specific motivations can be successfully leveraged to mobilize change.
La migration des magazines de mode féminins canadiens de langue française à l'ère du Web 20
Creators: name: Desjardins, Véronique
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Mass Communications.

description: Cette recherche porte sur la migration des magazines de mode féminins canadiens de langue française vers les plates-formes numériques telles le web et les dispositifs mobiles. Nous nous sommes intéressés aux objectifs, stratégies d'affaires et aux plans de développement derrière cette "net-amorphose" du magazine ainsi qu'aux types de pratiques proposées aux usagers. Nous avons effectué une analyse descriptive de sites web ainsi qu'une série d'entrevues semi-dirigées auprès de dix gestionnaires de trois magazines de mode canadiens de langue française, soit Loulou, Clin d'oeil et Elle Québec. Les résultats révèlent que ces magazines s'inspirent, à différents niveaux, de la logique du Web 2.0. Sous leur forme électronique, ces trois magazines favorisent des pratiques de type coopératives, interactives, collaboratives ainsi que participatives. Les contenus numériques développés pour les versions électroniques de ces magazines remplissent une fonction foncièrement utilitaire et tendent à être complémentaires à la version imprimée.
Structural explanation for how the BiP chaperone accelerates closure of Grp94 chaperone
Creators: name: Han, Luna
Publisher: name: Brandeis University
Year: 2024

description: BiP and Grp94, the endoplasmic reticulum (ER) paralogs of the highly conserved Hsp70 and Hsp90 chaperone families, work together in client protein folding and maturation. During their working cycle, BiP can directly bind to Grp94 and transfer a client protein to Grp94. BiP accelerates ATP-dependent closure of the Grp94 dimer by stabilizing a high-energy conformational intermediate of Grp94 (C’ state). However, the structural basis of this acceleration is unknown. A newly published cytosolic Hsp70/Hsp90 complex cryo-EM structure suggests a structure of the Grp94 C’ state, which shows a novel “interface II” between the Hsp70 nucleotide-binding domain (NBD) and Hsp90 N-terminal domain (NTD). Here I find that the interface II plays two important roles for BiP and Grp94. First, BiP accelerates Grp94 closure by stabilizing the high-energy C’ state via contacts at interface II. Second, a BiP/Grp94/client ternary complex is stabilized by interface II during client transfer. Surprisingly, interface II mutations on BiP greatly increase the affinity of BiP for clients under ATP conditions but not under ADP conditions, which opens a new possibility for understanding the mechanism by which BiP achieves high affinity for client proteins. Our results show that interface II is conserved between the ER and the cytosolic Hsp70/Hsp90 systems, which implies that their client transfer mechanism is conserved.