cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Enhancing SKIN health and safety in aged CARE (SKINCARE Trial): a study protocol for an exploratory cluster-randomized pragmatic trial
Creators: name: Kottner, Jan
name: Hahnel, Elisabeth
name: El Genedy, Monira
name: Neumann, Konrad
name: Balzer, Katrin
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Aged
subject: Dermatology
subject: Incontinence
subject: Intertrigo
subject: Nursing
subject: FOS: Health sciences
subject: Pressure ulcers
subject: Skin care
subject: Xerosis cutis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Aged long-term care receivers are affected by various adverse skin conditions like pressure ulcers, incontinence-associated dermatitis, dryness, intertrigo, and many more. Prevention of these skin problems and the provision of general hygiene and skin care activities are key areas of nursing practice. Numerous condition-specific guidelines are available and are implemented separately. On the other hand, there is huge overlap in terms of etiology, pathogenesis, and prevention of the skin conditions mentioned above. This leads to fragmented practice neglecting shared etiologies and prevention and treatment principles. Methods: The overall aims of this trial are to test the feasibility and to estimate possible effects of the implementation of a comprehensive skin care and prevention strategy targeting main nursing-relevant skin problems at the same time. A two-arm cluster-randomized controlled trial will be performed in 20 nursing homes randomly selected from the population of nursing homes of the state of Berlin, comparing skin care according to the skin care and prevention strategy with standard skin care. Discussion: It is expected that the implementation of this evidence-based skin care and prevention strategy will reduce the incidence of pressure ulcers, incontinence dermatitis, and other skin problems frequently related to care dependency. This trial will benefit individual patients and aged nursing home residents in general given the high prevalence and incidence of the addressed skin conditions. Findings of this exploratory trial may lay the foundation for a change in the development and evaluation of clinical standards and practices in general as it moves the perspective from individual conditions to a more comprehensive view on overlapping or coexisting health problems, in this case common skin conditions, in old-age long-term care receivers.
Conus coronatus Gmelin 1791
Creators: name: Franklin, J. Benjamin
name: Subramanian, K. A.
name: Fernando, S. Antony
name: Krishnan, K. S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Conidae
Conus
Conus coronatus

description: 17. Conus coronatus Gmelin, 1791 (Figure 18)
 Conus coronatus Gmelin, 1791: 3389, no. 39 (neotype, BMNH (27.5 x 16.5 mm) (Kohn 1966); " Australia ").
 Cucullus coronalis Röding, 1798: 38, nos. 478, 479 (refers to the original figure of C. coronatus Gmelin (Röckel et al. 1995); locality unknown).
 Conus parvus Gebauer, 1802: 7, no. 55 (representation of lectotype, Martini 1773: pl. 63, fig. 704 (30 x 18 mm) (Kohn 1981); locality unknown).
 Conus aristophanes “Duclos ” Sowerby II, 1857: 9, pl. 4, figs. 81, 82 (lectotype, BMNH (35.5 x 23 mm) (Coomans et al. 1981); "Philippine and Sandwitch Islands").
 Conus minimus Linnaeus var. condoriana Crosse & Fisher, 1864: 334 (holotype (21 x 12 mm) acc. Crosse & Fischer (Röckel et al. 1995); "Poulo-Condor, in the South China Sea, off Saigon").
 Material examined: MBMCS 117, 2 specimens, SL 37 mm; SW 26 mm.
 Description. Shell medium sized, moderately solid. Body whorl ventricosely conical, outline slightly convex, wider near the base. Shoulder sub-angulate, weakly tuberculate. Spire of low to moderate height. Aperture wide, outer lip convex.
Ground colour pinkish to violet, with pale bluish spiral bands below shoulder and centre. Spiral bands of variously sized brown and black markings on either side of sub-central band, overlaying the two solid colour bands. Spire similar to body colour. Aperture pale grey, edges tinged dark violet.
 Distribution. The occurrence of this species in the east coast was restricted to the islands of the Gulf of Mannar viz. Krusadai Island ([Chennappayya] 1927), Shingle Island (Satyamurti 1952), Krusadai Island and Mandapam Camp (Kohn 1978). In the west coast, Kohn (1978) collected specimens from Okha, Gujarat. He also reported museum specimens collected from Tuticorin (at BMNH) and Purnagath, Ratnagiri (at AMNH).
The specimens reported herein were collected from Keelakarai (Table 6) by diving in 12 m on sand and coral rubble and from the seaweed washed ashore.
 Remarks. In concurrence with previous records, the two specimens collected in this study were found off Keelakarai, approximately 50 km west of Krusadai Island and Mandapam Camp, where the species was previously reported. Conus coronatus is a rare species along the TamilNadu Coast. The present and previous reports suggest the distribution of this species is restricted to the Gulf of Mannar.
description: Published as part of Franklin, J. Benjamin, Subramanian, K. A., Fernando, S. Antony & Krishnan, K. S., 2009, 2250, pp. 1-63 in Zootaxa 2250 on page 26
Additional file 3 of Transcriptomic analysis of flower induction for long-day pitaya by supplementary lighting in short-day winter season
Creators: name: Xiong, Rui
name: Liu, Chengli
name: Xu, Min
name: Wei, Shuang-shuang
name: Huang, Jia-quan
name: Tang, Hua
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 3: Supplemental S3. NL-VS-L0 GO Enrichment (Molecular Function).
Lattice Boltzmann model for weakly compressible flows
Creators: name: Kolluru, Praveen Kumar
name: Atif, Mohammad
name: Namburi, Manjusha
name: Ansumali, Santosh
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computational Physics (physics.comp-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: Fluid Dynamics (physics.flu-dyn)
subject: FOS: Physical sciences

description: We present an energy conserving lattice Boltzmann model based on a crystallographic lattice for simulation of weakly compressible flows. The theoretical requirements and the methodology to construct such a model are discussed. We demonstrate that the model recovers the isentropic sound speed in addition to the effects of viscous heating and heat flux dynamics. Several test cases for acoustics, thermal and thermoacoustic flows are simulated to show the accuracy of the proposed model.
Use of quantitative T2 mapping for the assessment of renal cell carcinomas: first results
Creators: name: Adams, Lisa C.
name: Bressem, Keno K.
name: Jurmeister, Phillipp
name: Fahlenkamp, Ute L.
name: Ralla, Bernhard
name: Engel, Guenther
name: Hamm, Bernd
name: Busch, Jonas
name: Makowski, Marcus R.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: MRI mapping techniques
subject: Quantitative MRI
subject: T2 mapping
subject: Clear cell renal cell carcinoma
subject: Tumor grading
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Correct staging and grading of patients with clear cell renal cell carcinoma (cRCC) is of clinical relevance for the prediction of operability and for individualized patient management. As partial or radial resection with postoperative tumor grading currently remain the methods of choice for the classification of cRCC, non-invasive preoperative alternatives to differentiate lower grade from higher grade cRCC would be beneficial. Methods: This institutional-review-board approved cross-sectional study included twenty-seven patients (8 women, mean age ± SD, 61.3 ± 14.2) with histopathologically confirmed cRCC, graded according to the International Society of Urological Pathology (ISUP). A native, balanced steady-state free precession T2 mapping sequence (TrueFISP) was performed at 1.5 T. Quantitative T2 values were measured with circular 2D ROIs in the solid tumor portion and also in the normal renal parenchyma (cortex and medulla). To estimate the optimal cut-off T2 value for identifying lower grade cRCC, a Receiver Operating Characteristic Curve (ROC) analysis was performed and sensitivity and specificity were calculated. Students’ t-tests were used to evaluate the differences in mean values for continuous variables, while intergroup differences were tested for significance with two-tailed Mann-Whitney-U tests. Results: There were significant differences between the T2 values for lower grade (ISUP 1–2) and higher grade (ISUP 3–4) cRCC (p
Chiral restoration from pionic atoms?
Creators: name: Garcia-Recio, C.
name: Nieves, J.
name: Oset, E.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We evaluate widths and shifts of pionic atoms using a theoretical microscopical potential in which the pion decay constant $f_π$ is changed by an in--medium density dependent one ($f_π(ρ)$), predicted by different partial Chiral restoration calculations. We show that the results obtained for shifts and widths are worse than if this modification were not implemented. On the other hand, we argue that in microscopic many body approaches for the pion selfenergy, based on effective Lagrangians, the mechanisms responsible for the change of $f_π$ in the medium should be automatically incorporated. Therefore, the replacement of $f_π$ by $f_π(ρ)$ in the many body derivation of the microscopic potential would be inappropriate.
description: 10 pages, new comments and references added
Conditions for compatibility of quantum state assignments
Creators: name: Caves, Carlton M.
name: Fuchs, Christopher A.
name: Schack, Ruediger
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: Suppose N parties describe the state of a quantum system by N possibly different density operators. These N state assignments represent the beliefs of the parties about the system. We examine conditions for determining whether the N state assignments are compatible. We distinguish two kinds of procedures for assessing compatibility, the first based on the compatibility of the prior beliefs on which the N state assignments are based and the second based on the compatibility of predictive measurement probabilities they define. The first procedure leads to a compatibility criterion proposed by Brun, Finkelstein, and Mermin [BFM, Phys. Rev. A 65, 032315 (2002)]. The second procedure leads to a hierarchy of measurement-based compatibility criteria which is fundamentally different from the corresponding classical situation. Quantum mechanically none of the measurement-based compatibility criteria is equivalent to the BFM criterion.
description: REVTEX 4, 19 pages, 1 postscript figure
Analysis of outcomes and predictors of long-term survival following resection for retroperitoneal sarcoma
Creators: name: Malinka, Thomas
name: Nebrig, Maxim
name: Klein, Fritz
name: Pratschke, Johann
name: Bahra, Marcus
name: Andreou, Andreas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Retroperitoneal sarcoma
subject: Predictors
subject: Outcome
subject: Overall survival
subject: Disease-free survival
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Retroperitoneal sarcomas (RPS) include a heterogeneous group of rare malignant tumours, and various treatment algorithms are still controversially discussed until today. The present study aimed to examine postoperative and long-term outcomes after resection of primary RPS. Patients and methods: Clinicopathological data of patients who underwent resection of primary RPS between 2005 and 2015 were assessed, and predictors for overall survival (OS) and disease-free survival (DFS) were identified. Results: Sixty-one patients underwent resection for primary RPS. Postoperative morbidity and mortality rates were 31 and 3%, respectively. After a median follow-up time of 74 months, 5-year OS and DFS rates were 58 and 34%, respectively. Histologic high grade (5-year OS: G1: 92% vs. G2: 54% vs. G3: 43%, P = 0.030) was significantly associated with diminished OS in univariate and multivariate analyses. When assessing DFS, histologic high grade (5-year DFS: G1: 63% vs. G2: 24% vs. G3: 22%, P = 0.013), positive surgical resection margins (5-year DFS: R0: 53% vs. R1: 10% vs. R2: 0%, P = 0.014), and vascular involvement (5-year DFS: yes: 33% vs no: 39%, P = 0.001), were significantly associated with inferior DFS in univariate and multivariate analyses. Conclusions: High-grade tumours indicated poor OS, while vascular involvement, positive surgical resection margins, and histologic grade are the most important predictors of DFS. Although multimodal treatment strategies are progressively established, surgical resection remains the mainstay in the majority of patients with RPS, even in cases with vascular involvement.
Clustering of solutions in the symmetric binary perceptron
Creators: name: Baldassi, Carlo
name: Della Vecchia, Riccardo
name: Lucibello, Carlo
name: Zecchina, Riccardo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Disordered Systems and Neural Networks (cond-mat.dis-nn)
subject: Machine Learning (stat.ML)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The geometrical features of the (non-convex) loss landscape of neural network models are crucial in ensuring successful optimization and, most importantly, the capability to generalize well. While minimizers' flatness consistently correlates with good generalization, there has been little rigorous work in exploring the condition of existence of such minimizers, even in toy models. Here we consider a simple neural network model, the symmetric perceptron, with binary weights. Phrasing the learning problem as a constraint satisfaction problem, the analogous of a flat minimizer becomes a large and dense cluster of solutions, while the narrowest minimizers are isolated solutions. We perform the first steps toward the rigorous proof of the existence of a dense cluster in certain regimes of the parameters, by computing the first and second moment upper bounds for the existence of pairs of arbitrarily close solutions. Moreover, we present a non rigorous derivation of the same bounds for sets of $y$ solutions at fixed pairwise distances.
Electron dephasing near zero temperature: an experimental review
Creators: name: Lin, J. J.
name: Li, T. J.
name: Zhong, Y. L.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: FOS: Physical sciences

description: The behavior of the electron dephasing time near zero temperature, $τ_ϕ^0$, has recently attracted vigorous attention. This renewed interest is primarily concerned with whether $τ_ϕ^0$ should reach a finite or an infinite value as $T \to$ 0. While it is accepted that $τ_ϕ^0$ should diverge if there exists only electron-electron (electron-phonon) scattering, several recent measurements have found that $τ_ϕ^0$ depends only very weakly on temperature, if at all, when $T$ is sufficiently low. This article discusses the current experimental status of "the saturation problem", and concludes that the origin(s) for this widely observed saturation are still unresolved.
Approximating higher-order nonlinear QED processes with first-order building blocks
Creators: name: Dinu, Victor
name: Torgrimsson, Greger
Publisher: name: arXiv
Year: 2019
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: Higher-order tree-level processes in strong laser fields, i.e. cascades, are in general extremely difficult to calculate, but in some regimes the dominant contribution comes from a sequence of first-order processes, i.e. nonlinear Compton scattering and nonlinear Breit-Wheeler pair production. At high intensity the field can be treated as locally constant, which is the basis for standard particle-in-cell codes. However, the locally-constant-field (LCF) approximation and these particle-in-cell codes cannot be used when the intensity is only moderately high, which is a regime that is experimentally relevant. We have shown that one can still use a sequence of first-order processes to estimate higher orders at moderate intensities provided the field is sufficiently long. An important aspect of our new "gluing" approach is the role of the spin/polarization of intermediate particles, which is more nontrivial compared to the LCF regime.
description: Version 2: numerical results added before journal submission, previous results unchanged. 19 pages, 8 figures
Teisei zōyaku Sairan igen. Kan no 12
訂正増譯采覧異言.巻之十二
Creators: name: Yamamura, Masanaga.
Publisher: name: [place of publication unknown : publisher not identified]
Year: 2021

description: Cover title: 増譯采覧異言 Zōyaku Sairan igen (Enlarged Sairan igen); 采覧異言 Sairan igen is a geographical work by 新井白石 Arai Hakuseki in 1713. The 14 volumes include a preface volume, 12 volumes of text, and a volume of maps. The maps are coloured with the exception of the last four, which have only the boundaries outlined in red. All the maps occupy two facing pages, with one exception (Beans 1803.9) [East Indies]. Contents: (Beans 1803.1) 歐羅巴洲與地圖 Yōroppashū yochizu (General map of Europe); (Beans 1803.2) Horutogaru Isuhania Furansu Itaria Serumania Aran Heruheshia Suuyusserurando ijō nanakoku no zu (Map of the seven countries Portugal, Spain, France, Italy, Germany, Holland, and Switzerland); (Beans 1803.3) Teemaruka Noruweshiakoku Shueshiakoku ijō nikoku no zu [and] Koroodo Buritaniakoku no zu (Scandinavia [and] British Isles); (Beans 1803.4) [Balkans, Black Sea region and Asia Minor]; (Beans 1803.5) [Southern Russia and Poland]; (Beans 1803.6) 亞細亞洲與地圖 Ajiashū yochizu (General map of Asia); (Beans 1803.7) [East Asia]; (Beans 1803.8) [Southern Asia]; (Beans 1803.9) [East Indies]; (Beans 1803.10) 亞弗利加洲與地圖 Afurikashū yochizu (General map of Africa); (Beans 1803.11) 南亞墨利加洲與地圖 Minami Amerikashū yochizu (General map of South America); (Beans 1803.12) 北亞墨利加洲與地圖 Kita Amerikashū yochizu (General map of North America). Cited in: WSN; 125
Conus gubernator Hwass
Creators: name: Franklin, J. Benjamin
name: Subramanian, K. A.
name: Fernando, S. Antony
name: Krishnan, K. S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Conidae
Conus
Conus gubernator

description: 26. Conus gubernator Hwass in Bruguière, 1792 (Figure 27)
 Conus gubernator Hwass in Bruguière, 1792: 727–728, no. 121 (lectotype, MHNG (76 x 34 mm) (Kohn 1968); "Ocean asiatique").
 Conus terminus Lamarck, 1810: 426, no. 141 (representation of holotype, Kiener 1845: pl. 48, fig. 1d (83 x 32 mm) (Röckel et al. 1995); "Ocean asiatique").
 Conus leehmani Röckel & da Motta, 1979: 17–18 (holotype, MHNG (65.5 x 34 mm) (Röckel et al. 1995); " Maldive Is., Indian Ocean").
 Conus veillardi da Motta, 1990: 44–46 (holotype, MHNG (52.5 x 25.5 mm) (Röckel et al. 1995); "Glorieuses Islands, 11.30 S 47.20 E, western Indian Ocean").
 Material examined: MBMCS 126, 1 specimen, SL 43 mm; SW 18 mm.
 Description. Shell moderately large, solid to moderately heavy, glossy. Body whorl ventricosely conical; outline slightly convex adapically, straight below. Shoulder angulate. Spire of moderate height, bluntly pointed; outline slightly convex. Body whorl with several shallow spiral grooves on basal fourth to third, rest of the whorl smooth. Aperture uniformly wide, outer lip thin, sharp, straight.
Ground colour white suffused with light brown. Body whorl with separated blackish-brown axial markings; variable in shape and size, ranging from irregular flecks to large, zig-zag flames. Early spire whorls pinkish. Aperture white.
 Distribution. Melvill & Standen (1898) first reported C. gubernator from the Indian Coast. Satyamurti (1952) reported it from Pamban. Kohn (1978) reported specimens of C. gubernator deposited in BMNH and NMW.
The specimen described herein was collected from the Pamban shore (Table 6). The exact depth is not known.
  Remarks. Conus gubernator  appears to be a rare species along the TamilNadu Coast.
description: Published as part of Franklin, J. Benjamin, Subramanian, K. A., Fernando, S. Antony & Krishnan, K. S., 2009, 2250, pp. 1-63 in Zootaxa 2250 on page 31
Eternal Black Holes in AdS
Creators: name: Maldacena, Juan M.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We propose a dual non-perturbative description for maximally extended Schwarzschild Anti-de-Sitter spacetimes. The description involves two copies of the conformal field theory associated to the AdS spacetime and an initial entangled state. In this context we also discuss a version of the information loss paradox and its resolution.
description: v4: New section added on black holes with only one asymptotic boundary, v5,6: More references added
Conus longurionis Kiener 1845
Creators: name: Franklin, J. Benjamin
name: Subramanian, K. A.
name: Fernando, S. Antony
name: Krishnan, K. S.
Publisher: name: Zenodo
Year: 2009
Subjects: Biodiversity
Taxonomy
Animalia
Mollusca
Gastropoda
Neogastropoda
Conidae
Conus
Conus longurionis

description: 34. Conus longurionis Kiener, 1845 (Figure 35)
 Conus longurionis Kiener, 1845: pl. 92, fig. 6 (type, Coll. Prevost (33 x 10 mm) (Röckel et al. 1995); locality unknown). Conus kantanganus da Motta, 1982: 11–12, figs. 10a, b (holotype, MHNG (33 x 10 mm) (Röckel et al. 1995); "off the coast of Kantang, South West Thailand in the Andaman Sea").
 Material examined: MBMCS 134, 1 specimen, SL 37 mm; SW 12 mm.
 Description. Shell moderately small to medium sized, light. Body whorl usually narrowly conical, outline nearly straight. Shoulder sub-angulate, exhalent notch deep. Spire high, outline almost straight. First 3–10 post nuclear whorls tuberculate and distinct, sutures deep and wide. Body whorl with regularly spaced, axial striate spiral grooves and ribbons. Aperture long, narrow and slightly wide anteriorly.
Ground colour light brown. Body whorl with spiral rows of regular large brown dots on ribbons, partly fusing into irregularly sized axial flecks that cluster into spiral bands above and below centre. A weaker spiral band around shoulder. Aperture pale lavender.
 Distribution. The earliest published record of C. longurionis from India was from Gulf of Mannar (Thurston 1985). Subsequent records are from Madras (at AMNH) and Tranquebar (at ZMUC) (Kohn 1978).
The specimen reported herein was collected from the trash dumped on the fish-landing centre off Madras (Table 6).
 Remarks. Specimens from India and West Thailand were described as C. kantanganus (Röckel et al. 1995). C. kantanganus and the similar shells from Thailand and Philippines cannot be separated from C. longurionis at the species level and are considered geographical forms (Röckel et al. 1995). Since the shell characters of the specimens from Madras agree well with C. kantanganus, it is treated as C. longurionis.
description: Published as part of Franklin, J. Benjamin, Subramanian, K. A., Fernando, S. Antony & Krishnan, K. S., 2009, 2250, pp. 1-63 in Zootaxa 2250 on page 36
Generalizations of pp-wave spacetimes in higher dimensions
Creators: name: Coley, A.
name: Milson, R.
name: Pelavas, N.
name: Pravda, V.
name: Pravdová, A.
name: Zalaletdinov, R.
Publisher: name: arXiv
Year: 2002
Subjects: subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We shall investigate $D$-dimensional Lorentzian spacetimes in which all of the scalar invariants constructed from the Riemann tensor and its covariant derivatives are zero. These spacetimes are higher-dimensional generalizations of $D$-dimensional pp-wave spacetimes, which have been of interest recently in the context of string theory in curved backgrounds in higher dimensions.
description: 5 pages, RevTex, to appear in Physical Review D
Renal Fibrosis, Immune Cell Infiltration and Changes of TRPC Channel Expression after Unilateral Ureteral Obstruction in Trpc6-/- Mice
Creators: name: Kong, Weiying
name: Haschler, Timo Nicolas
name: Nürnberg, Bernd
name: Krämer, Stephanie
name: Gollasch, Maik
name: Markó, Lajos
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Inflammatory infiltration
subject: Renal fibrosis
subject: TRPC6
subject: Trpc channels
subject: UUO
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: BACKGROUND/AIMS: The transient receptor potential cation channel subfamily C member 6 (TRPC6) is a Ca2+-permeable nonselective cation channel and has received recent attention because of its capability to promote chronic kidney disease (CKD). The aims of this study were (i) to examine whether deletion of TRPC6 impacts on renal fibrosis and inflammatory cell infiltration in an early CKD model of unilateral ureter obstruction (UUO) in mice; and (ii) whether TRPC6-deficiency as well as UUO affect the regulation of TRPC expression in murine kidneys. METHODS: Wild-type (WT), Trpc6-knockout (Trpc6-/-) and New Zealand obese (NZO) mice underwent sham operation or unilateral ureteral obstruction (UUO). The kidneys were harvested 7 days after surgery. We examined renal fibrosis and inflammatory cell infiltration by histological and immunohistochemical staining. The mRNA expression of TRPC members and markers of fibrosis and inflammation in kidney were assessed by using real-time quantitative reverse transcription PCR. RESULTS: Histological and immunohistochemical analyses revealed less inflammatory cell infiltration (F4/80 and CD3) in UUO kidneys of Trpc6-/- mice compared to UUO kidneys of WT mice as well as less fibrosis. Genomic deletion of TRPC6 also affected the expression of pro-fibrotic genes in UUO Trpc6-/- kidneys compared to UUO WT kidneys while the expression of pro-inflammatory genes did not differ. UUO caused marked up-regulation of Trpc6 and down-regulation of Trpc1 mRNA in kidneys of WT and NZO mice. Trpc3 mRNA expression was significantly elevated in kidneys of Trpc6-/- mice underwent UUO while the levels did not change in kidneys of neither WT nor in NZO mice underwent UUO. CONCLUSION: TRPC6 contributes to renal fibrosis and immune cell infiltration in the UUO mouse model. Therefore, inhibition of TRPC6 emerges as a promising novel therapeutic strategy for treatment of chronic kidney failure in chronic obstructive nephropathy. However, confounding genomic and non-genomic effects of other TRPC channels should be taken into consideration to fully comprehend the renoprotective potential of targeting TRPC6 therapeutically under chronic kidney damaging conditions.
Future physics with polarized ep-colliders
Creators: name: De Roeck, A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We discuss some of the physics opportunities at polarized ep-colliders. Recent studies for polarized ep-colliders include HERA, EIC and THERA.
description: 7 pages, 6 figures, Invited talk presented at the ``International Workshop on the Spin Structure of the Proton and Polarized Collider Physics'', ECT, Trento, Italy, July 23-28, 2001
Summary of Five Years of Illinois Soybean Cyst Nematode Egg Count Samples Submitted to the  University of Illinois Plant Clinic
Creators: name: Plewa, Diane E. W.
name: Mahecha Bojaca, Esneider
Publisher: name: Zenodo
Year: 2024
Subjects: subject: Nematoda/pathogenicity

description: University of Illinois Plant Clinic; Abstract: Soybean cystnematode (Heterodera glycines, SCN) is the greatest yield limiting soybean pathogen in the United Statesand has been confirmed in over 80% of Midwest fields. Identifying SCN in the field can be challengingdue to non-specific symptoms that may resemble those caused by other biotic and abiotic issues. The factthat SCN is widespread, may be overlooked or misidentified in the field, and the potential for yield lossmake SCN one of the most important soybean pathogens in the US. Hence, regular sampling, earlydetection, and previous SCN field data can assist farmers in future integrated pest management (IPM)decisions. The data presented is of historical SCN egg counts classified by risk levels representing 2674soil samples from 74 Illinois counties submitted to the U of IL Plant Clinic from 2019 through 2023. Thiswork highlights the persistence of SCN in fields across Illinois. The number of samples submitted variedacross the years. The average risk levels for all samples were high (29.33% of samples), followed by low(26.37%), moderate (18.13%), none detected (14.4%), and extreme (8.7%). Despite variations in samplenumbers and egg counts from year to year, SCN risk levels remain consistently “high” in the state. Thesefindings underscore the importance of continued vigilance for this pathogen. The analysis of past SCNdata provides valuable insights for growers and researchers to develop IPM strategies for future seasons.
Universal superposition codes: capacity regions of compound quantum broadcast channel with confidential messages
Creators: name: Boche, Holger
name: Janßen, Gisbert
name: Saeedinaeeni, Sajad
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: We derive universal codes for transmission of broadcast and confidential messages over classical-quantum-quantum and fully quantum channels. These codes are robust to channel uncertainties considered in the compound model. To construct these codes we generalize random codes for transmission of public messages, to derive a universal superposition coding for the compound quantum broadcast channel. As an application, we give a multi-letter characterization of regions corresponding to the capacity of the compound quantum broadcast channel for transmitting broadcast and confidential messages simultaneously. This is done for two types of broadcast messages, one called public and the other common.
Additional file 6 of Transcriptomic analysis of flower induction for long-day pitaya by supplementary lighting in short-day winter season
Creators: name: Xiong, Rui
name: Liu, Chengli
name: Xu, Min
name: Wei, Shuang-shuang
name: Huang, Jia-quan
name: Tang, Hua
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 6: Supplemental S6. NL-VS-L1 GO Enrichment (Molecular Function).
Introducing an assessment tool based on a full set of end-of-training EPAs to capture the workplace performance of final-year medical students
Creators: name: Peters, Harm
name: Holzhausen, Ylva
name: Maaz, Asja
name: Driessen, Erik
name: Czeskleba, Anja
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Final-year clerkship
subject: Workplace performance
subject: Assessment
subject: EPAs
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: While literature on the theoretical value of entrustable professional activities (EPAs) for assessment is rapidly expanding, little experience exists on its application. The aims of this study are to develop and explore the utility of an EPA-based assessment tool for capturing the workplace performance of final-year medical students based on a full set of end-of-training EPAs. Methods: The tool was developed in a systematic iterative process. Twelve 12 end-of-undergraduate medical training EPAs were nested into 72 smaller EPAs and cross-mapped onto a 6-point supervision level scale, both adjusted to the context of final-year clerkships. One version was created for students’ self-assessment of their ability to carry out tasks and their history of carrying out tasks, and another version was created for supervisors’ assessment of students’ ability to carry out tasks. The tool was administered to final-year clerkship students and their clinical supervisors to explore its utility as an assessment approach. The results were analysed using descriptive and interferential statistics. Results: We enrolled a total of 60 final-year medical students. For 33 students, ratings were provided from one supervisor and for 27 students from two supervisors. With regard to the reliability and validity of the tool, students’ and supervisors’ ratings showed an overall good internal consistency as well as variability between and within the EPAs. Over the full EPA range, students rated their ability to perform a task slightly higher than their task performance history and slightly lower than the supervisors’ ratings. Students’ self-ratings of their ability to perform a task correlated with their history in performing the task. Supervisors’ ratings correlated among supervisors and not with students’ ratings. Concerning educational outcomes, supervisors’ average rating of students’ ability to perform the EPAs without direct supervision was 64%, and key findings being double-checked. Conclusions: This study introduces a tool that is adjusted to the final-year clerkship context and can assess the workplace performance of trainees based on a full set of end-of-training EPAs. Its utility characteristics suggest that the tool may be employed as a formative and outcome-aligned approach to the assessment of final-year students before entering into residency.
Immunologic cellular characteristics of the tumour microenvironment of hepatocellular carcinoma drive patient outcomes
Creators: name: Atanasov, Georgi
name: Dino, Karoline
name: Schierle, Katrin
name: Dietel, Corinna
name: Aust, Gabriela
name: Pratschke, Johann
name: Seehofer, Daniel
name: Schmelzle, Moritz
name: Hau, Hans-Michael
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: Hepatocellular carcinoma
subject: Monocytes/macrophages
subject: Tumour-infiltrating lymphocytes
subject: M2 macrophages
subject: Biomarkers
subject: Prognosis
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Anti-tumour immune competence has an impact in hepatocarcinogenesis and success of anti-cancer therapies. Tumour-infiltrating lymphocytes (TILs) and monocytes/macrophages (TAMs) are proposed to have significance in cancer. However, there is only limited data concerning their impact on patient outcome and survival in hepatocellular carcinoma (HCC). Methods: Frequencies of CD68+, CD163+M2-polarized TAMs and TILs were measured in de novo HCC tumours in noncirrhosis (n = 58) using immunohistology and correlated to patients’ clinicopathological characteristics and survival rates. Results: Patients with tumours marked by appearance of TILs and CD68+ TAMs showed an improved 1-, 3- and 5-year recurrence-free survival (all p ≤ 0.05). CD68+ TAMs were associated with reduced incidence of recurrent and multifocal disease. Conversely, CD163+ TAMs were associated with multifocal HCC and lymphangiosis carcinomatosa (all p ≤ 0.05). Conclusions: TILs and CD68+ TAMs are associated with multiple tumour characteristics and patient survival in HCC. However, there is only scarce data about the biology underlying their mechanistic involvement in human tumour progression. Thus, experimental data on functional links might help develop novel immunologic checkpoint inhibitor targets for liver cancer.
Disulfiram modulates ROS accumulation and overcomes synergistically cisplatin resistance in breast cancer cell lines
Creators: name: Yang, Zhi
name: Guo, Fang
name: Albers, Andreas E.
name: Sehouli, Jalid
name: Kaufmann, Andreas M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: ALDH enzyme activity
subject: ROS
subject: Chemotherapy resistance
subject: Cancer stem cells
subject: Novel adjuvant treatment
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The chemotherapeutic agent cisplatin typically induces apoptosis by inhibiting the cell cycle. Cancer Stem Cells (CSCs), which are a proliferative quiescent and slowly-cycling cell population, are less sensitive and therefore frequently spared from toxic effects. Thus, it remains a priority to increase the sensitivity of CSCs to cisplatin-based chemotherapy, or to specifically target CSCs to improve the therapeutic outcome in breast cancer. Disulfiram (DSF) is a drug used clinically for alcoholism treatment that has displayed promising anti-cancer activity in vitro and in cancer xenografts in breast cancer. Our study provides evidence that DSF inhibits Aldehyde dehydrogenase (ALDH) enzyme activity, inhibits the expression of stemness-related transcription factors (Sox, Nanog, Oct) in CSC derived from breast cancer cell lines, and modulates intracellular reactive oxygen species (ROS) generation. Importantly, our research proved that ALDH + stem-like cells play important roles in the resistance to the conventional chemotherapeutic agent cisplatin. DSF enhances the cytotoxic effect of cisplatin through inhibiting the stemness and by overcoming cisplatin resistance of ALDH + stem-like cells. A quantitative measurement showed the synergistic effect of DSF and cisplatin. Further, we show that ALDH+ cancer stem-like cells and ALDH- bulk cancer cells have different intrinsic ROS levels, what may explain differences in susceptibility to cisplatin treatment. Importantly, this difference is eliminated by DSF treatment making both cell types similarly susceptible for cytotoxic effects by cisplatin. These findings may influence chemotherapeutic treatment approaches in the future.
Evaluation of Effective Astrophysical S factor for Non-Resonant Reactions
Creators: name: Ueda, M.
name: Sargeant, A. J.
name: Pato, M. P.
name: Hussein, M. S.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Nuclear Theory (nucl-th)
subject: FOS: Physical sciences

description: We derived analytic formulas of the effective S astrophysical S factor,S^eff for a non-resonant reaction of charged particles using a Taylor expension of the astrophysical S factor and a uniform approximation.The formulas will be able to generate generate more accurate approximation to S^eff than previous ones.
Point Interactions: PT-Hermiticity and Reality of the Spectrum
Creators: name: Albeverio, S.
name: Fei, S. M.
name: Kurasov, P.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: General point interactions for the second derivative operator in one dimension are studied. In particular, ${\mathcal P \mathcal T}$-self-adjoint point interactions with the support at the origin and at points $\pm l$ are considered. The spectrum of such non-Hermitian operators is investigated and conditions when the spectrum is pure real are presented. The results are compared with those for standard self-adjoint point interactions.
description: 17 pages
Wonder is the beginning of wisdom! - Socrates - Albert Einstein, Carl Sagan, as well as the theologian Abraham Heschel, St. Gregory of Nyssa & Irish poet-theologian John O'Donohue & preface with Kant's "beauty" as the genesis of morals + Filipino "beauty of will" for comparison
Creators: name: Peck Jr, Charles E
Publisher: name: Knowledge Commons
Year: 2025

description: Socrates observed that "Wonder is the beginning of wisdom!" - "Where the imagination is alive, wonder is completely alive. When the imagination is alive, possibility is awake because imagination is the great friend of possibility. Possibilities are always more interesting than facts. We should not frown on facts, but our world is congested with them." John O'Donohue
Two thousand years ago, Aristotle remarked on the drive for understanding and knowledge when he stated, "All men desire knowledge!" - the desire for meaning being driven by a deep sense of awe and wonder for the "All", the world and the universe. Socrates' unspoken argument is that wonder, curiosity, and imagination are intimately connected with wisdom. Einstein observed that imagination was absolutely critical to all of his discoveries.
Additional file 7 of Transcriptomic analysis of flower induction for long-day pitaya by supplementary lighting in short-day winter season
Creators: name: Xiong, Rui
name: Liu, Chengli
name: Xu, Min
name: Wei, Shuang-shuang
name: Huang, Jia-quan
name: Tang, Hua
Publisher: name: figshare
Year: 2020
Subjects: subject: Genetics
subject: FOS: Biological sciences
subject: Plant Biology

description: Additional file 7: Supplemental S7. NL-VS-L1 GO Enrichment (Cellular Component).
Infrared permittivity of the biaxial van der Waals semiconductor $α$-MoO$_3$ from near- and far-field correlative studies
Creators: name: Álvarez-Pérez, Gonzalo
name: Folland, Thomas G.
name: Errea, Ion
name: Taboada-Gutiérrez, Javier
name: Duan, Jiahua
name: Martín-Sánchez, Javier
name: Tresguerres-Mata, Ana I. F.
name: Matson, Joseph R.
name: Bylinkin, Andrei
name: He, Mingze
name: Ma, Weiliang
name: Bao, Qiaoliang
name: Martín, José Ignacio
name: Caldwell, Joshua D.
name: Nikitin, Alexey Y.
name: Alonso-González, Pablo
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applied Physics (physics.app-ph)
subject: Materials Science (cond-mat.mtrl-sci)
subject: FOS: Physical sciences

description: The biaxial van der Waals semiconductor $α$-phase molybdenum trioxide ($α$-MoO$_3$) has recently received significant attention due to its ability to support highly anisotropic phonon polaritons (PhPs) -infrared (IR) light coupled to lattice vibrations in polar materials-, offering an unprecedented platform for controlling the flow of energy at the nanoscale. However, to fully exploit the extraordinary IR response of this material, an accurate dielectric function is required. Here, we report the accurate IR dielectric function of $α$-MoO$_3$ by modelling far-field, polarized IR reflectance spectra acquired on a single thick flake of this material. Unique to our work, the far-field model is refined by contrasting the experimental dispersion and damping of PhPs, revealed by polariton interferometry using scattering-type scanning near-field optical microscopy (s-SNOM) on thin flakes of $α$-MoO$_3$, with analytical and transfer-matrix calculations, as well as full-wave simulations. Through these correlative efforts, exceptional quantitative agreement is attained to both far- and near-field properties for multiple flakes, thus providing strong verification of the accuracy of our model, while offering a novel approach to extracting dielectric functions of nanomaterials, usually too small or inhomogeneous for establishing accurate models only from standard far-field methods. In addition, by employing density functional theory (DFT), we provide insights into the various vibrational states dictating our dielectric function model and the intriguing optical properties of $α$-MoO$_3$.
Anaphylaxis in Elderly Patients—Data From the European Anaphylaxis Registry
Creators: name: Aurich, Stefanie
name: Dölle-Bierke, Sabine
name: Francuzik, Wojciech
name: Bilo, Maria Beatrice
name: Christoff, George
name: Fernandez-Rivas, Montserrat
name: Hawranek, Thomas
name: Pföhler, Claudia
name: Poziomkowska-Gȩsicka, Iwona
name: Renaudin, Jean-Marie
name: Oppel, Eva
name: Scherer, Kathrin
name: Treudler, Regina
name: Worm, Margitta
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2019
Subjects: subject: anaphylaxis
subject: elderly
subject: insect venom
subject: drug hypersensitivity
subject: adrenaline
subject: hospitalization
subject: loss of consciousness
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Elicitors and symptoms of anaphylaxis are age dependent. However, little is known about typical features of anaphylaxis in patients aged 65 years or more. Methods: The data from the Network for Online Registration of Anaphylaxis (NORA) considering patients aged >= 65 (elderly) in comparison to data from adults (18-64 years) regarding elicitors, symptoms, comorbidities, and treatment measures were analyzed. Results: We identified 1,123 elderly anaphylactic patients. Insect venoms were the most frequent elicitor in this group (p < 0.001), followed by drugs like analgesics and antibiotics. Food allergens elicited less frequently anaphylaxis (p < 0.001). Skin symptoms occurred less frequently in elderly patients (77%, p < 0.001). The clinical symptoms were more severe in the elderly (51% experiencing grade III/IV reactions), in particular when skin symptoms (p < 0.001) were absent. Most strikingly, a loss of consciousness (33%, p < 0.001) and preexisting cardiovascular comorbidity (59%, p < 0.001) were more prevalent in the elderly. Finally, adrenaline was used in 30% of the elderly (vs. 26% in the comparator group, p < 0.001) and hospitalization was more often required (60 vs. 50%, p < 0.001). Discussion and Conclusion: Anaphylaxis in the elderly is often caused by insect venoms and drugs. These patients suffer more often from cardiovascular symptoms, receive more frequently adrenaline and require more often hospitalization. The data indicate that anaphylaxis in the elderly tends to be more frequently life threatening and patients require intensified medical intervention. The data support the need to recognize anaphylaxis in this patient group, which is prone to be at a higher risk for a fatal outcome.
Imaging Quasiparticle Interference in Bi2Sr2CaCu2O8+d
Creators: name: Hoffman, J. E.
name: McElroy, K.
name: Lee, D. -H.
name: Lang, K. M
name: Eisaki, H.
name: Uchida, S.
name: Davis, J. C.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Superconductivity (cond-mat.supr-con)
subject: FOS: Physical sciences

description: Scanning tunneling spectroscopy of the high-Tc superconductor Bi2Sr2CaCu2O8+d reveals weak, incommensurate, spatial modulations in the tunneling conductance. Images of these energy-dependent modulations are Fourier analyzed to yield the dispersion of their wavevectors. Comparison of the dispersions with photoemission spectroscopy data indicates that quasiparticle interference, due to elastic scattering between characteristic regions of momentum-space, provides a consistent explanation for the conductance modulations, without appeal to another order parameter. These results refocus attention on quasiparticle scattering processes as potential explanations for other incommensurate phenomena in the cuprates. The momentum-resolved tunneling spectroscopy demonstrated here also provides a new technique with which to study quasiparticles in correlated materials.
description: 10 pages text, 4 pages figures
Some New Results on Perfect Numbers.
Creators: name: Abiodun Adeyemi
Publisher: name: figshare
Year: 2019
Subjects: subject: 10101 Algebra and Number Theory
subject: FOS: Mathematics

description: A perfect number is any positive integer $n$ which satisfies $\sigma(n)=2n$, where $\sigma(n)$ is the sum of positive factors of $n$. In this paper, using Dickson's approach to Euler theorem on even perfect numbers, we seek an answer to a Suryanarayana's question which demands whether every odd perfect number is of the form $m\sigma(m)$. This paper thus gives the general form for perfect numbers with which it is possible to classify integers generally as perfect or non-perfect numbers. The form in this paper justifies Euclid-Euler's theorem, prunes Euler form for odd perfect numbers and allows us to give a remark concerning Suryanarayana's result that there is no odd super-perfect number of the form $p^{2\alpha}$. We also recommend some problems for further study.