cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Cerebral Ultrasound Time-Harmonic Elastography Reveals Softening of the Human Brain Due to Dehydration
Creators: name: Kreft, Bernhard
name: Bergs, Judith
name: Shahryari, Mehrgan
name: Danyel, Leon Alexander
name: Hetzer, Stefan
name: Braun, Jürgen
name: Sack, Ingolf
name: Tzschätzsch, Heiko
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: brain
subject: elastography
subject: hydration
subject: ultrasound
subject: time-harmonic elastography
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Hydration influences blood volume, blood viscosity, and water content in soft tissues - variables that determine the biophysical properties of biological tissues including their stiffness. In the brain, the relationship between hydration and stiffness is largely unknown despite the increasing importance of stiffness as a quantitative imaging marker. In this study, we investigated cerebral stiffness (CS) in 12 healthy volunteers using ultrasound time-harmonic elastography (THE) in different hydration states: (i) during normal hydration, (ii) after overnight fasting, and (iii) within 1 h of drinking 12 ml of water per kg body weight. In addition, we correlated shear wave speed (SWS) with urine osmolality and hematocrit. SWS at normal hydration was 1.64 ± 0.02 m/s and decreased to 1.57 ± 0.04 m/s (p < 0.001) after overnight fasting. SWS increased again to 1.63 ± 0.01 m/s within 30 min of water drinking, returning to values measured during normal hydration (p = 0.85). Urine osmolality at normal hydration (324 ± 148 mOsm/kg) increased to 784 ± 107 mOsm/kg (p < 0.001) after fasting and returned to normal (288 ± 128 mOsm/kg, p = 0.83) after water drinking. SWS and urine osmolality correlated linearly (r = -0.68, p < 0.001), while SWS and hematocrit did not correlate (p = 0.31). Our results suggest that mild dehydration in the range of diurnal fluctuations is associated with significant softening of brain tissue, possibly due to reduced cerebral perfusion. To ensure consistency of results, it is important that cerebral elastography with a standardized protocol is performed during normal hydration.
Alyxia flavescens Pitard
Creators: name: Middleton, David J.
name: Regalado Jr, Jacinto C.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Alyxia
Alyxia flavescens

description: Alyxia flavescens Pierre ex Pitard in Lecomte
Fl. Gén. Indo-Chine 3: 1127 (1933).
LECTOTYPE. — Pierre 4421 (HM), Vietnam, Dông Nai, Bao Chiang, designated by Lý, Feddes Repert. 97: 435 (1986).
description: Published as part of Middleton, David J. & Regalado Jr, Jacinto C., 2005, Nomenclatural notes on species of Apocynaceae described from Cambodia, Laos and Vietnam, pp. 291-308 in Adansonia (3) (3) 27 (2) on page 293, DOI: 10.5281/zenodo.5186636
FORMATION OF COMPETENCIES IN PRIMARY CLASSES OF BOARDING SCHOOLS FOR CHILDREN WITH HEARING IMPAIRMENT
Creators: name: Bannayeva, Matluba
name: Khushvaktov, Abror
Publisher: name: Zenodo
Year: 2024

description: In boarding schools for hearing-impaired children, their scientific competence is formed from the elementary grades. Competence is the process of applying the acquired knowledge, skills and abilities of the student in his life. Competences are also developed in mathematics lessons. Competencies are developed and technological approaches are used during their education.
Paragnetina Klapalek 1907
Creators: name: Judson, Sarah W.
name: Nelson, C. Riley
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Perlidae
Paragnetina

description: Paragnetina
 DIAGNOSIS: Male hemiterga are short, barely covering tergite 9 (Fig. 225), as compared to Agnetina which extend entirely across tergite 8. The hemitergal processes are abruptly bent at a 90 degree angle (Fig. 225), whereas those in Kamimuria are straight. The female subgenital plate is deeply notched and bilobed (Fig. 226), the lobes rounder and longer than Kamimuria which are pointed and short. The nymph lacks anal gills (Fig. 197) and has an incomplete setal fringe on the posterior margin of sternum 7 (Fig. 197), similar to Kamimuria but in contrast to Agnetina which has gills and a complete fringe. Head of nymph is distinct, with a pale, oval ocellar spot that is open posteriorly (Fig. 227), whereas Kamimuria has indistinct pale interocellar markings and Agnetina is entirely dark in the ocellar region.
 DISTRIBUTION—Global: Holarctic— Regional: AOB, IDB*— Aimag: BU^, KhG, KhD*, SE, TO^.
description: Published as part of Judson, Sarah W. & Nelson, C. Riley, 2012, 3541, pp. 1-118 in Zootaxa 3541 on page 38
Ferrisia multiformis Granara de Willink
Creators: name: Kaydan, M. B.
name: Gullan, P. J.
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hemiptera
Pseudococcidae
Ferrisia
Ferrisia multiformis

description: Ferrisia multiformis Granara de Willink
(Fig. 15)
 Ferrisia multiformis Granara de Willink, 1991 a: 181.
 This species was described and illustrated by Granara de Willink (1991) from Parthenium (Asteraceae) in Argentina based on the holotype and 10 paratype adult females (housed in IMLA, BMNH and USNM). We found no specimens of this species among the unidentified South American material that we examined. We examined the two paratype specimens housed in the USNM and noted the following diagnostic features: both pairs of ostioles are present, multilocular disc pores are present only posterior to the vulva, the dorsal enlarged tubular ducts never number more than two, the hind trochanter + femur is less than 300 µm long, with a ratio of hind trochanter + femur to tibia + tarsus of about 1.1, and the antennae are each about 400 µm long.
We have modified the original illustration of the adult female of this species (Fig. 15) based on examination of the paratypes in the USNM. The original drawing showed oral-collar tubular ducts dorsally, but this appears to be an error, possibly resulting from interpreting large discoidal pores as the openings of ducts.
description: Published as part of Kaydan, M. B. & Gullan, P. J., 2012, 3543, pp. 1-65 in Zootaxa 3543 on page 37
Binding Energy of Charged Excitons in ZnSe-based Quantum Wells
Creators: name: Astakhov, G. V.
name: Yakovlev, D. R.
name: Kochereshko, V. P.
name: Ossau, W.
name: Puls, J.
name: Henneberger, F.
name: Crooker, S. A.
name: McCulloch, Q.
name: Wolverson, D.
name: Gippius, N. A.
name: Faschinger, W.
name: Waag, A.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Strongly Correlated Electrons (cond-mat.str-el)
subject: FOS: Physical sciences

description: Excitons and charged excitons (trions) are investigated in ZnSe-based quantum well structures with (Zn,Be,Mg)Se and (Zn,Mg)(S,Se) barriers by means of magneto-optical spectroscopy. Binding energies of negatively () and positively (X+) charged excitons are measured as functions of quantum well width, free carrier density and in external magnetic fields up to 47 T. The binding energy of shows a strong increase from 1.4 to 8.9 meV with decreasing quantum well width from 190 to 29 A. The binding energies of X+ are about 25% smaller than the binding energy in the same structures. The magnetic field behavior of and X+ binding energies differ qualitatively. With growing magnetic field strength, increases its binding energy by 35-150%, while for X+ it decreases by 25%. Zeeman spin splittings and oscillator strengths of excitons and trions are measured and discussed.
Inflamm-Aging and Brain Insulin Resistance: New Insights and Role of Life-style Strategies on Cognitive and Social Determinants in Aging and Neurodegeneration
Creators: name: Komleva, Yulia
name: Chernykh, Anatoly
name: Lopatina, Olga
name: Gorina, Yana
name: Lokteva, Irina
name: Salmina, Alla
name: Gollasch, Maik
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: aging
subject: inflammation
subject: inflammasome
subject: metaflammasome
subject: insulin resistance
subject: Alzheimer's disease
subject: anti-inflammatory strategies
subject: calorie restriction
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Over the past decades, the human life span has dramatically increased, and therefore, a steady increase in diseases associated with age (such as Alzheimer's disease and Parkinson's disease) is expected. In these neurodegenerative diseases, there is a cognitive decline and memory loss, which accompany increased systemic inflammation, the inflamm-aging, and the insulin resistance. Despite numerous studies of age-related pathologies, data on the contribution of brain insulin resistance and innate immunity components to aging are insufficient. Recently, much research has been focused on the consequences of nutrients and adiposity- and nutrient-related signals in brain aging and cognitive decline. Moreover, given the role of metainflammation in neurodegeneration, lifestyle interventions such as calorie restriction may be an effective way to break the vicious cycle of metainflammation and have a role in social behavior. The various effects of calorie restriction on metainflammation, insulin resistance, and neurodegeneration have been described. Less attention has been paid to the social determinants of aging and the possible mechanism by which calorie restriction might influence social behavior. The purpose of this review is to discuss current knowledge in the interdisciplinary field of geroscience-immunosenescence, inflamm-aging, and metainflammation-which makes a significant contribution to aging. A substantial part of the review is devoted to frontiers in the brain insulin resistance in relation to neuroinflammation. In addition, we summarize new data on potential mechanisms of calorie restriction that influence as a lifestyle intervention on the social brain. This knowledge can be used to initiate successful aging and slow the onset of neurodegenerative diseases.
Scalable Unix Commands for Parallel Processors: A High-Performance Implementation
Creators: name: Ong, E.
name: Lusk, E.
name: Gropp, W.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Distributed, Parallel, and Cluster Computing (cs.DC)
subject: FOS: Computer and information sciences
subject: D.1.3

description: We describe a family of MPI applications we call the Parallel Unix Commands. These commands are natural parallel versions of common Unix user commands such as ls, ps, and find, together with a few similar commands particular to the parallel environment. We describe the design and implementation of these programs and present some performance results on a 256-node Linux cluster. The Parallel Unix Commands are open source and freely available.
description: 9 pages, 2 figures
Laser-scribed reduced graphene oxide as counter electrode for dye-sensitized solar cell
Creators: name: Zengze Chu
name: Yimeng Wang
name: Jiao, Lin
name: Xinxi Zhang
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Plant Biology

description: Reduced graphene oxide (rGO) has been attracted considerable attention in the field of dye sensitized solar cells (DSSCs) to serve as a low cost and earth-abundant alternative to the conventional platinum-based counter electrodes. Recently direct laser writing technologies are emerging as an inexpensive, time-efficient and high-resolution method to produce catalytic rGO-based electrodes. Herein, we experimentally demonstrate that the laser-scribed rGO on ITO/PEN substrate was produced by a commercial LightScribe DVD burner and used as counter electrode for DSSC. SEM and Raman spectroscopy characterizations reveal that after laser-scribing rGO film presents a roughness structure with multi-layer curled or tilting graphenes. The cyclic voltammetry (CV) and electrochemical impedance spectrum (EIS) analyses were also conducted to explore its electrocatalytic activity and charge-transfer properties. Finally, the DSSC based on rGO counter electrode achieved a power conversion efficiency of 2.07% under one sun AM 1.5 G illumination. This work developed a simple and promising laser-scribing method to prepare rGO-based counter electrode materials for DSSCs applications.
Bound-State Band Reconstruction and Resonance in Spin-1/2 Bose Gas with 1D Spin-Orbit Coupling
Creators: name: Gu, Qi
name: Xiong, Yuncheng
name: Yin, Lan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Gases (cond-mat.quant-gas)
subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: In this work, we study two-body bound states in two-component Bose gas with a one-dimensional (1D) spin-orbit coupling (SOC) induced by Raman lasers. The finite Raman coupling strength generates coupling among three spin channels, resulting in the reconstruction of three bound-state bands. In addition, multiple resonances can be induced at finite scattering lengths. By tuning the interaction in one intra-species channel, one bound-state band can be lifted and three resonances can be achieved at different center-of-mass momenta, which can be observable under current experimental conditions in ${}^{87}$Rb atoms.
description: 5 pages, 4 figures
title: Programme SHCC, cycle 9, Corps, séances du 19 novembre 2015 au 2 juin 2016
Creators: name: Gauthier, Christophe
name: Juan, Myriam
name: Kerlan, Anne
name: Leventopoulos, Mélisande
name: Vezyroglou, Dimitri
name: Séminaire Histoire Culturelle Du Cinéma
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2021

description: Relation: http://purl.org/poi/crdo.vjf.cnrs.fr/cocoon-bafdd7fd-36d5-48cb-bdd7-fd36d5e8cb85
Modulation of Liver Inflammation and Fibrosis by Interleukin-37
Creators: name: Mountford, Steffeni
name: Effenberger, Maria
name: Noll-Puchta, Heidi
name: Griessmair, Lucas
name: Ringleb, Andrea
name: Haas, Sonja
name: Denk, Gerald
name: Reiter, Florian P.
name: Mayr, Doris
name: Dinarello, Charles A.
name: Tilg, Herbert
name: Bufler, Philip
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: TGF-β
subject: Smad3
subject: liver inflammation
subject: serum levels
subject: IL-37
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background and Aims: Chronic inflammation induces liver fibrosis, cirrhosis and potentially liver cancer. Kupffer cells modulate hepatic stellate cells by secreting immunologically active proteins as TGF-beta. TGF-beta promotes liver fibrosis via the activation of Sma- and Mad-related protein 3. IL-37 broadly suppresses innate and adaptive immune responses. Intracellular IL-37 interacts with Smad3. We hypothesize that IL-37 downregulates the activation of hepatic Kupffer and stellate cells and interferes with the TGF-beta signaling cascade to modulate liver fibrogenesis. Methods: The role of IL-37 on liver inflammation and fibrogenesis was assessed in three mouse models as well as isolated Kupffer- and stellate cells. Serum IL-37 was tested by ELISA in a clinical cohort and correlated with liver disease severity. Results: Transgene expression of IL-37 in mice extends survival, reduces hepatic damage, expression of early markers of fibrosis and histologically assessed liver fibrosis after bile duct ligation. IL-37tg mice were protected against CCl4-induced liver inflammation. Colitis-associated liver inflammation and fibrosis was less severe in IL-10 knockout IL-37tg mice. Spontaneous and LPS/TGF-beta-induced cytokine release and profibrogenic gene expression was lower in HSC and KC isolated from IL-37tg mice and IL-37 overexpressing, IL-1 beta stimulated human LX-2 stellate cells. However, administration of recombinant human IL-37 did not modulate fibrosis pathways after BDL in mice, LX2 cells or murine HSCs. In a large clinical cohort, we observed a positive correlation of serum IL-37 levels with disease severity in liver cirrhosis. Conclusions: Predominantly intracellular IL-37 downregulates liver inflammation and fibrosis. The correlation of serum IL-37 with disease severity in cirrhosis suggests its potential as a novel target modulating the course of liver fibrosis.
KAON Factory engineering design and impact study : report of the Steering Committee
Creators: name: Elliot, John
Publisher: name: TRIUMF
Year: 2017

description: This document is the concluding report of the Steering Committee appointed by Ministers for Canada and British Columbia under the terms of the 1988 Canada-British Columbia Agreement on the Proposed KAON Factory Engineering Design and Impact Study. This report summarizes the results and findings of the complete study, full details of which are provided in nine accompanying technical reports . The study represents the final step in the conventional process of developing a major science initiative for decision by government. Where the initial concept for a KAON Factory was put forward and developed by TRIUMF in 1985 as the initial proposal , the current $11 million study brings together a fully developed proposal and an assessment of its feasibility, costs, support and implications
An Economic Risk Analysis of No-till Management for the Rice-Soybean Rotation System used in Arkansas
Creators: name: Hristovska, Tatjana
name: Watkins, K. Bradley
name: Anders, Merle M.
name: Hristovska, Tatjana
name: Watkins, K. Bradley
name: Anders, Merle M.
Publisher: name: Unknown
Year: 2012
Subjects: subject: Environmental Economics and Policy
subject: Farm Management
subject: Resource /Energy Economics and Policy
subject: simulation
subject: rice-soybean
subject: no tillage-profitability
subject: risk analysis

description: Arkansas is the top domestic rice producer, representing nearly half of total U.S. rice production. Sediment is one of the major pollutants in rice producing areas of Arkansas. In order to mitigate this problem no-tillage management is often recommended. No-tillage is not well understood by farmers who believe that no-till is less profitable due to lower yields offsetting cost savings. This study evaluates the profitability and variability of no-till in the typical rice-soybean rotation used in Arkansas rice production. Crop yields, prices and prices for key production inputs (fuel and fertilizer) are simulated for the rotation, and net return distributions for rice, soybean and the two-year rotation are evaluated for no-till and conventional till using stochastic efficiency with respect to a function (SERF) analysis. The results indicate that both risk neutral and risk-averse rice producers would prefer no-till over conventional till management in the two year rice-soybean rotation, and that no-till soybeans contribute greatly to the overall profitability of the rotation.
Scattering and radiation damping in gyroscopic Lorentz electrodynamic
Creators: name: Appel, Walter
name: Kiessling, Michael K. -H.
Publisher: name: arXiv
Year: 2001
Subjects: subject: Mathematical Physics (math-ph)
subject: Dynamical Systems (math.DS)
subject: FOS: Physical sciences
subject: FOS: Mathematics

description: Relativistic massive Lorentz electrodynamics (LED) is studied in a ``gyroscopic setup'' where the electromagnetic fields and the particle spin are the only dynamical degrees of freedom. A rigorous proof of the global existence and uniqueness of the dynamics is given for essentially the whole range of field strengths reasonable for a classical theory. For a class of rotation-reflection symmetric field data it is shown that the dynamics also satisfies the world-line equations for a non-moving Lorentz electron, thus furnishing rigorous solutions of the full system of nonlinear equations of LED. The previously proven soliton dynamics of the Lorentz electron is further illucidated by showing that rotation-reflection symmetric deviations from the soliton state of the renormalized particle die out exponentially fast through radiation damping if the electrostatic mass is smaller than the bare rest mass.
description: Final version. To appear in Lett. Math. Phys. (LaTeX, 20 pages)
No Impact of Functional Connectivity of the Motor System on the Resting Motor Threshold: A Replication Study
Creators: name: Engelhardt, Melina
name: Komnenić, Darko
name: Roth, Fabia
name: Kawelke, Leona
name: Finke, Carsten
name: Picht, Thomas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: resting motor threshold
subject: transcranial magnetic stimulation
subject: functional connectivity
subject: resting-state fMRI
subject: variability
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The physiological mechanisms of corticospinal excitability and factors influencing its measurement with transcranial magnetic stimulation are still poorly understood. A recent study reported an impact of functional connectivity (FC) between the primary motor cortex (M1) and the dorsal premotor cortex (PMd) on the resting motor threshold (RMT) of the dominant hemisphere. We aimed to replicate these findings in a larger sample of 38 healthy right-handed subjects with data from both hemispheres. Resting-state FC was assessed between the M1 and five a priori defined motor-relevant regions on each hemisphere as well as interhemispherically between both primary motor cortices. Following the procedure by the original authors, we included age, cortical gray matter volume, and coil-to-cortex distance (CCD) as further predictors in the analysis. We report replication models for the dominant hemisphere as well as an extension to data from both hemispheres and support the results with Bayes factors. FC between the M1 and the PMd did not explain the variability in the RMT, and we obtained moderate evidence for the absence of this effect. In contrast, CCD could be confirmed as an important predictor with strong evidence. These findings contradict the previously proposed effect, thus questioning the notion of the PMd playing a major role in modifying corticospinal excitability.
The Cantor set of linear orders on N is the universal minimal S_\infty-system
Creators: name: Glasner, Eli
Publisher: name: arXiv
Year: 2002
Subjects: subject: Dynamical Systems (math.DS)
subject: FOS: Mathematics
subject: 22A05, 22A10, 54H20

description: Each topological group $G$ admits a unique universal minimal dynamical system $(M(G),G)$. When $G$ is a non-compact locally compact group the phase space $M(G)$ of this universal system is non-metrizable. There are however topological groups for which $M(G)$ is the trivial one point system (extremely amenable groups), as well as topological groups $G$ for which $M(G)$ is a metrizable space and for which there is an explicit description of the dynamical system $(M(G),G)$. One such group is the topological group $S_\infty$ of all permutations of the integers ${\mathbb Z}$, with the topology of pointwise convergence. We show that $(M(S_\infty),S_\infty)$ is a symbolic dynamical system (hence in particular $M(S_\infty)$ is a Cantor set), and give a full description of all its symbolic factors. Among other facts we show that $(M(G),G)$ (and hence also every minimal $S_\infty$) has the structure of a two-to-one group extension of proximal system and that it is uniquely ergodic.
description: 5 pages. The results in this article will be treated fully in an article, written jointly with B. Weiss, to be published in Geometric and Functional Analysis (GAFA)
title: Endangered Species Act (ESA) Section 7(a)(2)Biological Opinion and Magnuson–Stevens Fishery Conservation and Management Act Essential Fish Habitat Consultationfor the Natural Resource Management Routine Boat Dock and Ramp Maintenance Project
Creators: name: United States. National Marine Fisheries Service. West Coast Region
Publisher: name: United States. National Marine Fisheries Service. West Coast Region
Year: 2021

description: ESA Section 7 Consultation ; WCRO-2020-03326
SARS-CoV-2 Proteome-Wide Analysis Revealed Significant Epitope Signatures in COVID-19 Patients
Creators: name: Schwarz, Tatjana
name: Heiss, Kirsten
name: Mahendran, Yuvaraj
name: Casilag, Fiordiligie
name: Kurth, Florian
name: Sander, Leif E.
name: Wendtner, Clemens-Martin
name: Hoechstetter, Manuela A.
name: Müller, Marcel A.
name: Sekul, Renate
name: Drosten, Christian
name: Stadler, Volker
name: Corman, Victor M.
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: antibody response
subject: epitope identification
subject: B cells
subject: diagnostic
subject: respiratory tract infection
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: The WHO declared the COVID-19 outbreak a public health emergency of international concern. The causative agent of this acute respiratory disease is a newly emerged coronavirus, named SARS-CoV-2, which originated in China in late 2019. Exposure to SARS-CoV-2 leads to multifaceted disease outcomes from asymptomatic infection to severe pneumonia, acute respiratory distress and potentially death. Understanding the host immune response is crucial for the development of interventional strategies. Humoral responses play an important role in defending viral infections and are therefore of particular interest. With the aim to resolve SARS-CoV-2-specific humoral immune responses at the epitope level, we screened clinically well-characterized sera from COVID-19 patients with mild and severe disease outcome using high-density peptide microarrays covering the entire proteome of SARS-CoV-2. Moreover, we determined the longevity of epitope-specific antibody responses in a longitudinal approach. Here we present IgG and IgA-specific epitope signatures from COVID-19 patients, which may serve as discriminating prognostic or predictive markers for disease outcome and/or could be relevant for intervention strategies.
The Effectiveness of Sentiment Analysis for Detecting Fine-grained Service Quality
Creators: name: Rahimi, Mohammad Masoud
name: ELHAM NAGHI ZADEH KAKHKI
name: STEPHAN WINTER
name: MARK STEVENSON
Publisher: name: The University of Auckland
Year: 2019
Subjects: subject: 90903 Geospatial Information Systems
subject: FOS: Environmental engineering

description: Improving public transport relies on the development of appropriate tools for measuring and monitoring service quality. While there are several studies exploring perceived service quality, these works are mainly based on surveys, which are limited to a pre-de fined period and do not enable to constantly observe and analyze the respond of passengers to different events. As a result, they may miss events affecting service quality in a transport hub. In contrast, social media feeds provide an opportunity to constantly look for events that may affect the service quality. However, in a confi ned geographic area like a transport hub, the sparsity of data considerably reduce the effectiveness of straight-forward event detection methods. In contrastto earlier works and in order to face these challenges, in this paper, we explore the effectiveness of sentiment analysis to detect events impacting perceived service quality in a con fined location. Southern Cross Station, a major transport hub in Melbourne, Australia, is selected as a casestudy. Moreover, a statistical approach to combine and integrate sentiment-based and frequency-basedevent detection is proposed. Main findings con rm the effectiveness of sentiment analysis for detecting events affecting service quality in a transport hub. Additionally, the results prove that the proposed method can improve the sensitivity of event detection for events affectingservice quality.
Alyxia marginata Pitard
Creators: name: Middleton, David J.
name: Regalado Jr, Jacinto C.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Alyxia
Alyxia marginata

description: Alyxia marginata Pitard in Lecomte
Fl. Gén. Indo-Chine 3: 1123 (1933).
LECTOTYPE. — Poilane 3783 (HM), Vietnam, Khanh Hoa, West of Nha Trang, between Song-tan and Do-ut, designated by L´y, Feddes Repert. 97: 435 (1986).
description: Published as part of Middleton, David J. & Regalado Jr, Jacinto C., 2005, Nomenclatural notes on species of Apocynaceae described from Cambodia, Laos and Vietnam, pp. 291-308 in Adansonia (3) (3) 27 (2) on page 293, DOI: 10.5281/zenodo.5186636
Haploperla Navas 1934
Creators: name: Judson, Sarah W.
name: Nelson, C. Riley
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Chloroperlidae
Haploperla

description: Haploperla
 DIAGNOSIS: A distinct, wide, brown stripe from head to 10th tergum is present in this monotypic genus in Mongolia (Fig. 115). Alaskaperla and many other Mongolian chloroperlids are similarly striped, but all lack the characteristic dark, central, head marking present on Haploperla. The male epiproct is short, flat, and forming a small triangle (Fig. 116). Female subgenital plate round and (Zwick 2007) barely protruding (Fig. 117). Nymphs have similar coloration (Fig. 118) to the adult. Nymphs are also characterized by unique hair features, with whorls of apical hairs on the cercal segments and long pronotal hairs on the posterior and anterior margins, but lacking or having sparse hairs along the lateral margin of the pronotum.
 DISTRIBUTION—Global: Nearctic & East Palearctic— Regional: AOB, IDB, POB*— Aimag: AR*, BO, BU, DO*, KhE*, KhG^,SE^, TO, UB.
description: Published as part of Judson, Sarah W. & Nelson, C. Riley, 2012, 3541, pp. 1-118 in Zootaxa 3541 on page 26
Activation of Tripartite Motif Containing 63 Expression by Transcription Factor EB and Transcription Factor Binding to Immunoglobulin Heavy Chain Enhancer 3 Is Regulated by Protein Kinase D and Class IIa Histone Deacetylases
Creators: name: Pablo Tortola, Cristina
name: Fielitz, Britta
name: Li, Yi
name: Rüdebusch, Julia
name: Luft, Friedrich C.
name: Fielitz, Jens
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: muscle atrophy
subject: protein kinase D
subject: HDAC = histone deacetylase
subject: transcription factor EB
subject: TFE3
subject: muscle ring finger protein 1
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Rationale: The ubiquitin-proteasome system (UPS) is responsible for skeletal muscle atrophy. We showed earlier that the transcription factor EB (TFEB) plays a role by increasing E3 ubiquitin ligase muscle really interesting new gene-finger 1(MuRF1)/tripartite motif-containing 63 (TRIM63) expression. MuRF 1 ubiquitinates structural proteins and mediates their UPS-dependent degradation. We now investigated how TFEB-mediated TRIM63 expression is regulated. Objective: Because protein kinase D1 (PKD1), histone deacetylase 5 (HDAC5), and TFEB belong to respective families with close structural, regulatory, and functional properties, we hypothesized that these families comprise a network regulating TRIM63 expression. Methods and Results: We found that TFEB and transcription factor for immunoglobulin heavy-chain enhancer 3 (TFE3) activate TRIM63 expression. The class IIa HDACs HDAC4, HDAC5, and HDAC7 inhibited this activity. Furthermore, we could map the HDAC5 and TFE3 physical interaction. PKD1, PKD2, and PKD3 reversed the inhibitory effect of all tested class IIa HDACs toward TFEB and TFE3. PKD1 mediated nuclear export of all HDACs and lifted TFEB and TFE3 repression. We also mapped the PKD2 and HDAC5 interaction. We found that the inhibitory effect of PKD1 and PKD2 toward HDAC4, HDAC5, and HDAC7 was mediated by their phosphorylation and 14-3-3 mediated nuclear export. Conclusion: TFEB and TFE3 activate TRIM63 expression. Both transcription factors are controlled by HDAC4, HDAC5, HDAC7, and all PKD-family members. We propose that the multilevel PKD/HDAC/TFEB/TFE3 network tightly controls TRIM63 expression.
Graded activity is an important component in cognitive behavioral therapy to reduce severe fatigue: results of a pragmatic crossover trial in cancer survivors
Creators: name: H. J. G. Abrahams
name: M. F. M. Gielissen
name: A. M. J. Braamse
name: G. Bleijenberg
name: L. M. Buffart
name: H. Knoop
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Medicine
subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences

description: Background: Fatigue is one of the most common and distressing long-term effects of cancer treatment. Cognitive behavioral therapy (CBT) is an evidence-based intervention for patients with severe post-cancer fatigue. CBT for fatigue is a complex intervention consisting of multiple elements like a graded activity program, regulation of the sleep-wake rhythm and reformulation of fatigue-related cognitions. The contribution of the separate elements to the positive effect of CBT on fatigue is unclear. The main objective of this pragmatic crossover trial was comparing the efficacy of graded activity with the other elements of CBT in reducing post-cancer fatigue. Material and methods: Severely fatigued cancer survivors were randomized to (i) graded activity followed by the other elements of CBT after crossover (n = 41), or (ii) the two components in reverse order (n = 48). Fatigue severity was measured at baseline, before crossover and after CBT (Checklist Individual Strength (CIS), Fatigue Severity subscale). Differences in effects on fatigue were examined with a linear regression analysis. Objective physical activity, perceived activity and self-efficacy were explored as mediators of the effect of graded activity. Results: Before crossover, the reduction in fatigue was significantly larger after graded activity than after the other elements (β = 4.75, 95% confidence interval (95% CI) = −9.19; −0.32). An increase in perceived activity mediated this effect (β = −4.17, 95% CI = −7.37; −1.37). Conclusions: Graded activity is an important component of CBT for post-cancer fatigue as it resulted in a larger reduction in fatigue compared with the other elements, mediated by an increased level of perceived activity. Results indicated that the other elements of CBT are of added value in reducing fatigue.
KAON Factory study : accelerator review committee report
Creators: name: TRIUMF-KAON Project
Publisher: name: TRIUMF
Year: 2017

description: The TRIUMF-KAON Project will provide a unique world-class facility for basic research in particle and nuclear physics with performance capabilities which will not be available anywhere else. The committee unanimously agrees that the project is technically mature and urges that funding be secured to pursue the construction with the utmost urgency. The Specific Terms of References are addressed in the following.1. Technical Assessment of the Design. 2. Progress of Technical Projects During the Past Year. 3. Degree of Readiness. 4. Cost, Schedule and Manpower. 5. Staging the Project
The design of an agent based model of human activities and communications in cardiac resuscitation
Creators: name: Mancheva, Lyuba
name: Dugdale, Julie
Publisher: name: arXiv
Year: 2019
Subjects: subject: Computers and Society (cs.CY)
subject: Multiagent Systems (cs.MA)
subject: FOS: Computer and information sciences

description: Cardio-pulmonary arrest is a common emergency situation causing over 400,000 deaths per year, more than a 1000 per day, in the USA alone. The goal of this work is to develop an agent based computer simulator that will allow trainers to experiment with different communication protocols, such as those found in air traffic control. This paper describes the first step in designing the simulator development. The design is based on an analysis of communications during real life training simulations using the FIPA standard categories.
Market Competitiveness and Demographic Profiles of Dairy Alternative Beverages in the United States: The Case of Soymilk
Creators: name: Dharmasena, Senarath
name: Capps, Oral
name: Dharmasena, Senarath
name: Capps, Oral
Publisher: name: Unknown
Year: 2012
Subjects: subject: Agribusiness
subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Marketing
subject: FOS: Economics and business
subject: Soymilk
subject: white milk
subject: flavored milk
subject: Nielsen HomeScan data
subject: tobit procedure

description: Data from U.S. households for year 2008 were used in examining market competitiveness of soymilk using tobit procedure. Unconditional own- and cross-price elasticities are larger than their conditional counterparts. Income, age, employment status, education level, race, ethnicity, region and presence of children are significant drivers affecting the demand for soymilk.
Nonideal quantum detectors in Bayesian formalism
Creators: name: Korotkov, Alexander N.
Publisher: name: arXiv
Year: 2002
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Quantum Physics (quant-ph)
subject: FOS: Physical sciences

description: The Bayesian formalism for a continuous measurement of solid-state qubits is derived for a model which takes into account several factors of the detector nonideality. In particular, we consider additional classical output and backaction noises (with finite correlation), together with quantum-limited output and backaction noises, and take into account possible asymmetry of the detector coupling. The formalism is first derived for a single qubit and then generalized to the measurement of entangled qubits.
description: 10 pages
The Basic Path of Modern Agriculture with Chinese Characteristics-Industry Nurturing Agriculture
Creators: name: Zhang, Feng-Yun
name: Zhang, Feng-Yun
Publisher: name: Unknown
Year: 2011
Subjects: subject: Agribusiness
subject: Industry nurturing agriculture
subject: Modern agriculture
subject: Path
subject: China

description: Constructing the modern agriculture with Chinese characteristics is the path and direction for solving issues concerning agriculture, countryside and farmers in China, the key to new village construction, the important measure for promoting overall agriculture production capacity, and the prerequisite and guarantee for coordinating urban-rural development. At present, the level of agriculture mechanization in China is promoted steadily; the science and technology are applied to agriculture extensively; the agriculture regionalization layout gradually takes shape; the agriculture industrialization management develops steadily. Be that as it may, the overall quality of farmers is low; the agriculture infrastructure is weak; the agriculture resources are limited; the inputs of agriculture science and technology are short. These hamper the development of modern agriculture. We should implement ' industry nurturing agriculture through capital support and policy guidance, reform household registration system; connect the fragmented land into parcel; encourage the leading enterprises to develop in rural areas; establish agriculture cooperative organizations; deepen rural financial system reform; quicken the promotion and application of agriculture technology . These measures can effectively promote the development of agriculture, and realize the agriculture modernization in China.
Multiscale Visual Drilldown for the Analysis of Large Ensembles of Multi-Body Protein Complexes
Creators: name: Furmanová, Katarína
name: Jurčík, Adam
name: Kozlíková, Barbora
name: Hauser, Helwig
name: Byška, Jan
Publisher: name: arXiv
Year: 2019
Subjects: subject: Human-Computer Interaction (cs.HC)
subject: Biomolecules (q-bio.BM)
subject: FOS: Computer and information sciences
subject: FOS: Biological sciences

description: When studying multi-body protein complexes, biochemists use computational tools that can suggest hundreds or thousands of their possible spatial configurations. However, it is not feasible to experimentally verify more than only a very small subset of them. In this paper, we propose a novel multiscale visual drilldown approach that was designed in tight collaboration with proteomic experts, enabling a systematic exploration of the configuration space. Our approach takes advantage of the hierarchical structure of the data -- from the whole ensemble of protein complex configurations to the individual configurations, their contact interfaces, and the interacting amino acids. Our new solution is based on interactively linked 2D and 3D views for individual hierarchy levels and at each level, we offer a set of selection and filtering operations enabling the user to narrow down the number of configurations that need to be manually scrutinized. Furthermore, we offer a dedicated filter interface, which provides the users with an overview of the applied filtering operations and enables them to examine their impact on the explored ensemble. This way, we maintain the history of the exploration process and thus enable the user to return to an earlier point of the exploration. We demonstrate the effectiveness of our approach on two case studies conducted by collaborating proteomic experts.
Alyxia pisiformis Pitard
Creators: name: Middleton, David J.
name: Regalado Jr, Jacinto C.
Publisher: name: Zenodo
Year: 2005
Subjects: Biodiversity
Taxonomy
Plantae
Tracheophyta
Magnoliopsida
Gentianales
Apocynaceae
Alyxia
Alyxia pisiformis

description: Alyxia pisiformis Pitard in Lecomte
Fl. Gén. Indo-Chine 3: 1126 (1933).
LECTOTYPE. — Pierre 96 (HM), Vietnam, Dông Nai, Mt Dinh, designated by L´y, Feddes Repert. 97: 435 (1986).
Second step lectotypification, designated here (there were three undifferentiated specimens of Pierre 96 at HM).
description: Published as part of Middleton, David J. & Regalado Jr, Jacinto C., 2005, Nomenclatural notes on species of Apocynaceae described from Cambodia, Laos and Vietnam, pp. 291-308 in Adansonia (3) (3) 27 (2) on pages 293-294, DOI: 10.5281/zenodo.5186636
Deep Phenotyping of CD11c+ B Cells in Systemic Autoimmunity and Controls
Creators: name: Rincon-Arevalo, Hector
name: Wiedemann, Annika
name: Stefanski, Ana-Luisa
name: Lettau, Marie
name: Szelinski, Franziska
name: Fuchs, Sebastian
name: Frei, Andreas Philipp
name: Steinberg, Malte
name: Kam-Thong, Tony
name: Hatje, Klas
name: Keller, Baerbel
name: Warnatz, Klaus
name: Radbruch, Andreas
name: Lino, Andreia C.
name: Schrezenmeier, Eva
name: Dörner, Thomas
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: B cell
subject: SLE
subject: pSS
subject: lupus
subject: CD11c
subject: atypical B cells
subject: CD21
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Circulating CD11c+ B cells are a key phenomenon in certain types of autoimmunity but have also been described in the context of regular immune responses (i.e., infections, vaccination). Using mass cytometry to profile 46 different markers on individual immune cells, we systematically initially confirmed the presence of increased CD11c+ B cells in the blood of systemic lupus erythematosus (SLE) patients. Notably, significant differences in the expression of CD21, CD27, and CD38 became apparent between CD11c- and CD11c+ B cells. We observed direct correlation of the frequency of CD21-CD27- B cells and CD21-CD38- B cells with CD11c+ B cells, which were most pronounced in SLE compared to primary Sjögren's syndrome patients (pSS) and healthy donors (HD). Thus, CD11c+ B cells resided mainly within memory subsets and were enriched in CD27-IgD-, CD21-CD27-, and CD21-CD38- B cell phenotypes. CD11c+ B cells from all donor groups (SLE, pSS, and HD) showed enhanced CD69, Ki-67, CD45RO, CD45RA, and CD19 expression, whereas the membrane expression of CXCR5 and CD21 were diminished. Notably, SLE CD11c+ B cells showed enhanced expression of the checkpoint molecules CD86, PD1, PDL1, CD137, VISTA, and CTLA-4 compared to HD. The substantial increase of CD11c+ B cells with a CD21- phenotype co-expressing distinct activation and checkpoint markers, points to a quantitative increased alternate (extrafollicular) B cell activation route possibly related to abnormal immune regulation as seen under the striking inflammatory conditions of SLE which shows a characteristic PD-1/PD-L1 upregulation.
Suwallia Ricker 1943
Creators: name: Judson, Sarah W.
name: Nelson, C. Riley
Publisher: name: Zenodo
Year: 2012
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Plecoptera
Chloroperlidae
Suwallia

description: Suwallia
 DIAGNOSIS: The general color of species in this genus is yellow in both life and when preserved in alcohol (Fig. 120), with dark pigmentation in the ocellar triangle, dark antennae, thin medial and peripheral stripes on the pronotum, U-shaped markings on the meso- and metanota, and a wide medial abdominal stripe extending most of the length of the abdomen. On males, setose finger-like medially-directed hemitergal processes originate from segment 10 (Fig. 123). The unhinged, knob-like epiproct (Fig. 123) is distinct from all other Chloroperlidae. The female subgenital plate covers sternum 8 and gradually narrows to a rounded or truncate apex (Fig. 124), covering much of sternum 9 as well. The nymphs exhibit distinct dark pigmentation (Fig. 129) between and anterior to the ocellar region, and have dense dark hairs in patches on thoracic sterna.
 DISTRIBUTION—Global: Nearctic & East Palearctic— Regional: AOB, IDB— Aimag: AR, BO, BU^, GA^, KhD, KhG, OV^, SE, TO, UB*,UV*, ZA.
 DISCUSSION: Suwallia is the most common genus of Chloroperlidae in Mongolia and is found in a large variety of habitat types. Detailed species descriptions and SEMs are given in Alexander and Stewart (1999).
description: Published as part of Judson, Sarah W. & Nelson, C. Riley, 2012, 3541, pp. 1-118 in Zootaxa 3541 on page 27
Systemic Chemotherapy Including Ramucirumab in Combination With Pressurized Intra-Peritoneal Aerosol Chemotherapy Is a Safe Treatment Option for Peritoneal Metastasis of Gastric Cancer
Creators: name: Feldbrügge, Linda
name: Gronau, Felix
name: Brandl, Andreas
name: Auer, Timo Alexander
name: Oeff, Alan
name: Thuss-Patience, Peter
name: Pratschke, Johann
name: Rau, Beate
Publisher: name: Charité - Universitätsmedizin Berlin
Year: 2021
Subjects: subject: gastric cancer
subject: peritoneal metastasis
subject: pressurized intraperitoneal aerosol chemotherapy
subject: ramucirumab
subject: peritoneal chemotherapy
subject: 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

description: Background: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a laparoscopic technique for local chemotherapy. It has been used for treatment of peritoneal metastasis of gastric cancer (PM GC) in combination with systemic therapy. VEGFR2 antagonist ramucirumab is a second-line therapy for GC, and has been suspected to cause wound healing disorders. Methods: This is a retrospective single center cohort study of patients with PM GC, who received PIPAC treatment in combination with systemic chemotherapy with and without ramucirumab. Data on patients' characteristics and their perioperative courses were collected and complication rates were compared with regard to preoperative use of ramucirumab and time between last dose of systemic therapy and PIPAC treatment. Results: Fifty patients underwent 90 PIPAC treatments for PM GC in 3 years. Overall postoperative morbidity was 11% with 6% severe complications. The mean interval between systemic therapy and PIPAC was 20 days. Neither the length of interval nor the use of ramucirumab had an effect on complication rates. Conclusion: Our study suggests that addition of ramucirumab to pre-PIPAC systemic therapy, irrespective of the length of the treatment-free interval before PIPAC, does not increase the risk of postoperative complications and is therefore a safe option for treatment of PM GC.