cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Videobasierte Lehrmodule zur Förderung der professionellen Wahrnehmung von heterogenitätssensiblem Unterricht
Creators: name: Junker, Robin
name: Rauterberg, Till
name: Möller, Kornelia
name: Holodynski, Manfred
Publisher: name: Herausforderung Lehrer*innenbildung - Zeitschrift zur Konzeption, Gestaltung und Diskussion
Year: 2020

description: Der Beitrag erläutert den gemeinsamen konzeptuellen Rahmen der fachspezifischen videobasierten Lehrmodule zur Förderung der professionellen Unterrichtswahrnehmung von Lehramtsstudierenden, die im Rahmen der Qualitätsoffensive Lehrerbildung Münster konzipiert und evaluiert wurden. Dazu gehört das Konstrukt der professionellen Unterrichtswahrnehmung und des übergreifenden Analyseschwerpunkts, des Umgangs mit einer heterogenen Schülerschaft im Unterricht, sowie das gemeinsame didaktische Konzept der videobasierten Seminare. Auf der Basis dieser fachlichen Grundlegung stellen die Autoren ein mediendidaktisches Konzept vor, das die kategoriengeleitete Analyse von Unterrichtsvideos als zentrales Aufgabenformat verwendet. Anhand evidenzbasierter mediendidaktischer Prinzipien wird der gemeinsame didaktische Rahmen der videobasierten Seminarkonzepte beschrieben. Dieser Rahmen soll Anregungen für die Konzeption weiterer videobasierter Lehrmodule für andere Unterrichtsfächer und zu weiteren Analyseschwerpunkten bieten. Zum übergreifenden didaktischen Rahmen gehören (1) die Produktion und Auswahl geeigneter Unterrichtsvideos, (2) die Konstruktion von Aufgaben zur videobasierten Unterrichtsanalyse und (3) die Zusammenstellung dieser Aufgaben zu einem schlüssigen und wirksamen Seminarkonzept. Abschließend wird das gemeinsame Evaluationskonzepts der videobasierten Seminare erläutert.
description: Herausforderung Lehrer*innenbildung - Zeitschrift zur Konzeption, Gestaltung und Diskussion, Bd. 3 Nr. 1 (2020): Herausforderung Lehrer_innenbildung - Ausgabe 3
High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation
Creators: name: Kesselmeier, Miriam
name: Pütter, Carolin
name: Anna-Lena Volckmar
name: Baurecht, Hansjörg
name: Grallert, Harald
name: Illig, Thomas
name: Khadeeja Ismail
name: Ollikainen, Miina
name: Silén, Yasmina
name: Keski-Rahkonen, Anna
name: Bulik, Cynthia M.
name: Collier, David A.
name: Zeggini, Eleftheria
name: Hebebrand, Johannes
name: Scherag, André
name: Hinney, Anke
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: 19999 Mathematical Sciences not elsewhere classified
subject: FOS: Mathematics
subject: Cancer

description: Objectives: Patients with anorexia nervosa (AN) are ideally suited to identify differentially methylated genes in response to starvation. Methods: We examined high-throughput DNA methylation derived from whole blood of 47 females with AN, 47 lean females without AN and 100 population-based females to compare AN with both controls. To account for different cell type compositions, we applied two reference-free methods (FastLMM-EWASher, RefFreeEWAS) and searched for consensus CpG sites identified by both methods. We used a validation sample of five monozygotic AN-discordant twin pairs. Results: Fifty-one consensus sites were identified in AN vs. lean and 81 in AN vs. population-based comparisons. These sites have not been reported in AN methylation analyses, but for the latter comparison 54/81 sites showed directionally consistent differential methylation effects in the AN-discordant twins. For a single nucleotide polymorphism rs923768 in CSGALNACT1 a nearby site was nominally associated with AN. At the gene level, we confirmed hypermethylated sites at TNXB. We found support for a locus at NR1H3 in the AN vs. lean control comparison, but the methylation direction was opposite to the one previously reported. Conclusions: We confirm genes like TNXB previously described to comprise differentially methylated sites, and highlight further sites that might be specifically involved in AN starvation processes.
The role of the bile salt surfactant sodium deoxycholate in aqueous two-phase separation of single-wall carbon nanotubes revealed by systematic parameter variations
Creators: name: Defillet, Joeri
name: Avramenko, Marina
name: Martinati, Miles
name: Carillo, Miguel Ángel López
name: Van der Elst, Domien
name: Wenseleers, Wim
name: Cambré, Sofie
Publisher: name: arXiv
Year: 2022
Subjects: subject: Mesoscale and Nanoscale Physics (cond-mat.mes-hall)
subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: Aqueous two-phase (ATP) extraction has been demonstrated as a fast, scalable, and effective separation technique to sort single-wall carbon nanotubes (SWCNTs) according to their diameter and chiral structure. The exact mechanism behind the chirality-dependent migration of SWCNTs between the two phases is however not completely understood, and depends on many parameters (e.g., choice of surfactants and their concentration, pH, temperature, ...), making it difficult to optimize the multivariable parameter space. In this work, we present a systematic study of the choice and concentration of specific surfactants on the ATP sorting, by performing a series of single-step ATP separations in which each time only one parameter is systematically varied, while monitoring the structure-specific migration of every SWCNT chirality between both phases with detailed wavelength-dependent spectroscopy. These systematic studies reveal that the diameter-dependent stacking of a discrete number of sodium deoxycholate molecules fitting around the SWCNT circumference determines the separation order in the form of a periodically modulated pattern as a function of SWCNT diameter. Addition of cosurfactants can be used to compete with the bile salt surfactant to enhance the separation yields, but does not affect the sorting order. The results are afterwards directly applied to predict the parameters required to separate specific chiral structures in just two ATP steps.
Geomorphology of the Slovak Karst (Eastern Part)
Creators: name: Gessert, Alena
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Pharmacology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: Ecology
subject: Developmental Biology
subject: Cancer

description: The Slovak Karst region is an interesting European area that consists of karst plateaus at heights of 550–700 m, divided by deep gorges 300–400 m in depth. Gorges have classical fluviokarstic genesis with caves situated on the slopes indicating valley evolution during the Quaternary. During our geomorphological research, two plateaus were mapped – Jasov and Zádiel near the city of Košice. Due to the lack of typical karst forms, these plateaus are considered as less developed karst. According to our mapping, karst forms do in fact exist here, but the density and size of depressions are smaller than the western-situated plateaus. The dolines are not typical in that the shape and plateau relief is flat with east facing hills and valleys. The result of our field work is a geomorphological map at a scale of 1:10,000 involving the main geomorphological forms of diverse origin and age. Morphometric analyses of surface depressions were used to compare the Slovak Karst plateaus with other karst areas.
Additional file 1 of Risk assessment and prediction for lung cancer among Hong Kong Chinese men
Creators: name: Tse, Lap Ah
name: Wang, Feng
name: Wong, Martin Chi-sang
name: Au, Joseph Siu-kei
name: Yu, Ignatius Tak-sun
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Environmental Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Cancer
subject: Plant Biology
subject: FOS: Biological sciences

description: Additional file 1.
Non-Markovian random walks characterize network robustness to nonlocal cascades
Creators: name: Valente, Angelo
name: De Domenico, Manlio
name: Artime, Oriol
Publisher: name: arXiv
Year: 2022
Subjects: subject: Physics and Society (physics.soc-ph)
subject: Statistical Mechanics (cond-mat.stat-mech)
subject: FOS: Physical sciences

description: Localized perturbations in a real-world network have the potential to trigger cascade failures at the whole system level, hindering its operations and functions. Standard approaches analytically tackling this problem are mostly based either on static descriptions, such as percolation, or on models where the failure evolves through first-neighbor connections, crucially failing to capture the nonlocal behavior typical of real cascades. We introduce a dynamical model that maps the failure propagation across the network to a self-avoiding random walk that, at each step, has a probability to perform nonlocal jumps toward operational systems' units. Despite the inherent non-Markovian nature of the process, we are able to characterize the critical behavior of the system out of equilibrium, as well as the stopping time distribution of the cascades. Our numerical experiments on synthetic and empirical biological and transportation networks are in excellent agreement with theoretical expectation, demonstrating the ability of our framework to quantify the vulnerability to nonlocal cascade failures of complex systems with interconnected structure.
Evidence assessments and guideline recommendations in Lyme disease: the clinical management of known tick bites, erythema migrans rashes and persistent disease
Creators: name: Cameron, Daniel J
name: Johnson, Lorraine B
name: Maloney, Elizabeth L
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Medicine
subject: Biotechnology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: FOS: Biological sciences
subject: Sociology
subject: FOS: Sociology
subject: Cancer
subject: Science Policy
subject: 111714 Mental Health
subject: FOS: Health sciences
subject: 110309 Infectious Diseases

description: Evidence-based guidelines for the management of patients with Lyme disease were developed by the International Lyme and Associated Diseases Society (ILADS). The guidelines address three clinical questions – the usefulness of antibiotic prophylaxis for known tick bites, the effectiveness of erythema migrans treatment and the role of antibiotic retreatment in patients with persistent manifestations of Lyme disease. Healthcare providers who evaluate and manage patients with Lyme disease are the intended users of the new ILADS guidelines, which replace those issued in 2004 (Exp Rev Anti-infect Ther 2004;2:S1–13). These clinical practice guidelines are intended to assist clinicians by presenting evidence-based treatment recommendations, which follow the Grading of Recommendations Assessment, Development and Evaluation system. ILADS guidelines are not intended to be the sole source of guidance in managing Lyme disease and they should not be viewed as a substitute for clinical judgment nor used to establish treatment protocols.
Two Novel Spectrophotometric Methods for Determination of Naproxen via a Modulation to Hydroxy Analog
Creators: name: Sh.Mahmood, Hana
Publisher: name: King Mongkut's Institute of Technology Ladkrabang
Year: 2020
Subjects: Naproxen, modulation, oxidation, potassium permanganate

description: Current Applied Science and Technology, 20, 2, 295-309
title: Influences of stress phenotype, nutrition and genetic background on the upper thermal tolerance of Atlantic salmon (Salmo salar)
Creators: name: Ignatz, Eric Hans
Publisher: name: Memorial University of Newfoundland
publisherIdentifier: https://ror.org/04haebc03
publisherIdentifierScheme: ROR
Year: 2024

description: Anthropogenic climate change threatens the sustainability of the Atlantic salmon (Salmo salar) aquaculture industry. This thesis studied the effects of three factors [i) stress phenotype; ii) supplemental dietary cholesterol; and iii) family/genetic background] on the performance of farmed Atlantic salmon when exposed to an incremental thermal maximum (ITMax, +0.2°C day⁻¹) challenge that mimicked natural summer sea-cage conditions. No differences in the ITMax of male Atlantic salmon characterized as either low (LR) or high stress responders (HR) based on measurements of post-stress cortisol levels at 9°C was found, and interestingly, stress phenotypes were no longer distinguishable from one another when post-stress cortisol levels were analyzed at elevated temperatures. However, some differences in gene expression were found between LR and HR fish in response to bacterial immune stimulation. Notably, HR salmon mounted a greater (p < 0.05) innate antibacterial immune response than LR salmon at 20°C, whereas LRs had a greater (p = 0.057) response among stress-related transcripts relative to HR fish at 12°C. Supplemental dietary cholesterol did not affect the ITMax of female triploid Atlantic salmon. However, ≤ 5% of the salmon (irrespective of diet) died before temperature reached 22°C, and this suggests that the commercial production of triploids is possible in eastern Canada. In addition, inclusion of +1.30 and 1.76% cholesterol in the diet reduced fillet bleaching above 18°C. Finally, family-based differences in ITMax were detected in diploid, mixed sex, Atlantic salmon, with a 1.7°C separation between the least and most tolerant families. This study also showed that ITMax is a more sensitive and relevant indicator of upper thermal tolerance than the more common/convenient approach of assessing a fish’s critical thermal maximum (CTMax). In the final chapter of this thesis, I characterized the four paralogues of serpinh1 [alias heat shock protein 47 (hsp47)] in Atlantic salmon. This is a well-established biomarker of heat stress in salmonids, and the reported data provide important insights into the evolutionary history and regulatory functions of this essential gene. Overall, this thesis provides novel information on how the Atlantic salmon aquaculture industry can most effectively assess upper thermal tolerance, and navigate this era of accelerated climate change.
Geographic nestedness of Lyciasalamandra billae (Amphibia: Salamandridae) populations within L. antalyana and description of a new subspecies
Creators: name: Godmann, Olaf
name: Kariş, Mert
name: Göçmen, Bayram
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A new subspecies of the Bille’s Lycian Salamander Lyciasalamandra billae is described from four localities in the vicinity of Geyikbayɪrɪ nearby Antalya, Turkey. It is distinguished from the nominotypical subspecies by colouration and surface pattern. The distribution area of the new subspecies is nested within the range of Lyciasalamandra antalyana, with L. a. gocmeni bordering in the north and the range of L. a. antalyana bordering in the south. New localities of both L. antalyana subspecies are reported. http://www.zoobank.org/urn:lsid:zoobank.org:pub:8F541E98-61F3-4EDD-A432614B0A250711
Additional file 2: of trumpet: transcriptome-guided quality assessment of m6A-seq data
Creators: name: Zhang, Teng
name: Zhang, Shao-Wu
name: Zhang, Lin
name: Meng, Jia
Publisher: name: figshare
Year: 2018
Subjects: subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified
subject: Information Systems not elsewhere classified
subject: Mathematical Sciences not elsewhere classified
subject: Developmental Biology
subject: Marine Biology
subject: Inorganic Chemistry
subject: FOS: Chemical sciences
subject: Science Policy

description: Supplementary Material (including Table S1-S4) for trumept.Â (DOCX 21Â kb)
Optimal tigecycline dosage regimens in patients infected with carbapenem-resistant Enterobacteriaceae
Creators: name: Wichai Santimaleeworagun
name: Weerayuth Saelim
name: Sudaluck Thunyaharn
name: Jatapat Hemapanpairoa
name: Piraporn Juntanawiwat
Publisher: name: Silpakorn University Research, Innovation and Creativity Administration Office
Year: 2020
Subjects: critically ill patients
gram-negative bacteria
Monte Carlo simulation
MIC

description: Science, Engineering and Health Studies, 14, 1, 1-7
Geographic nestedness of Lyciasalamandra billae (Amphibia: Salamandridae) populations within L. antalyana and description of a new subspecies
Creators: name: Godmann, Olaf
name: Kariş, Mert
name: Göçmen, Bayram
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Microbiology
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: Ecology
subject: 69999 Biological Sciences not elsewhere classified
subject: Cancer
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: A new subspecies of the Bille’s Lycian Salamander Lyciasalamandra billae is described from four localities in the vicinity of Geyikbayɪrɪ nearby Antalya, Turkey. It is distinguished from the nominotypical subspecies by colouration and surface pattern. The distribution area of the new subspecies is nested within the range of Lyciasalamandra antalyana, with L. a. gocmeni bordering in the north and the range of L. a. antalyana bordering in the south. New localities of both L. antalyana subspecies are reported. http://www.zoobank.org/urn:lsid:zoobank.org:pub:8F541E98-61F3-4EDD-A432614B0A250711
Bioactive terpenoids from Croton laui
Creators: name: Li, Fei
name: Zhang, Dong-Bo
name: Li, Jing-Tao
name: He, Feng-Jie
name: Zhu, Hong-Li
name: Li, Nan
name: Xiao, Xin-Chun
name: Ren, Li
name: Zheng, Wei
Publisher: name: Taylor & Francis
Year: 2019
Subjects: subject: Biochemistry
subject: Pharmacology
subject: Environmental Sciences not elsewhere classified
subject: Chemical Sciences not elsewhere classified
subject: Ecology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Hematology
subject: Plant Biology
subject: Virology

description: Two new highly-oxygenated neo-clerodane diterpenoids, 3S-acetoxyl-mollotucin D dilactone ester (1) and 6S-crotoeurin C (2), and a new lupane-type triterpene, 16β-hydroxyl-3β-O-trans-coumaroyl-betulin (6), as well as three known analogues (3–5) were obtained from the leaves of Croton laui. The structures of the new compounds were determined by extensive spectroscopic methods, and their absolute configurations were determined by combination of single-crystal X-ray diffraction analysis, electronic circular dichroism (ECD) spectra, and literature data. Compounds 2 and 3 exhibited inhibitory activities of lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 macrophages with IC50 values of 1.2 and 1.6 μM, respectively. Additionally, compound 6 exhibited activity against Col205 and HepG2 cell lines with IC50 values of 12.9 and 17.7 μM, respectively.
LASER PROJECTOR-ASSISTED COMPOSITE MANUFACTURING
Creators: name: He, Yuwei
Publisher: name: Purdue University Graduate School
Year: 2024
Subjects: classificationCode: 401602
subject: Composite and hybrid materials
classificationCode: 401407
subject: Manufacturing management
classificationCode: 401402
subject: CAD/CAM systems

description: Composite materials have gained popularity and favor in the aviation and aerospace industries. Their distinctive blend of properties transformed the design and material selection of aircraft and spacecraft, providing significant advantages in terms of weight reduction, fuel efficiency, structural integrity, and environmental sustainability. While multiple automated technologies for composite manufacturing, such as the AFP/ATL machine's robotic arms, are currently being used in the industry, manual layup is still the primary choice for complicated geometry and small-scale manufacturing. For manual layup assistance, physical templates and a laser projector can assist the laminator for ply placement. However, physical templates can be costly, complicated to manufacture, and inefficient. On the other hand, the implementation of laser projection can assist the laminator with ply placement seed point identification and eliminate the need for a physical template, making it a more sustainable option. This study is designed to determine whether the laser projector can assist the laminator in ensuring a constant overlap length, which might improve material structural performance and reduce manufacturing time.
Vanishing S-curvature of Randers spaces
Creators: name: Ohta, Shin-ichi
Publisher: name: arXiv
Year: 2009
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We give a necessary and sufficient condition on a Randers space for the existence of a measure for which Shen's S-curvature vanishes everywhere. Moreover, such a measure coincides with the Busemann-Hausdorff measure up to a constant multiplication.
description: 7 pages (no change from v1); Corrigendum is available at http://www4.math.sci.osaka-u.ac.jp/~sohta/ ; See also my book "Comparison Finsler geometry" https://link.springer.com/book/10.1007/978-3-030-80650-7
Grain size effect on the plastic deformation of nanocrystalline silver
Creators: name: Sun, Qian
name: Fenying Wang
name: Yajun Gao
name: Jianwei Zhao
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: 29999 Physical Sciences not elsewhere classified
subject: FOS: Physical sciences
subject: Cell Biology
subject: Genetics
subject: FOS: Biological sciences
subject: Molecular Biology
subject: Physiology
subject: Evolutionary Biology
subject: 59999 Environmental Sciences not elsewhere classified
subject: FOS: Earth and related environmental sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: Developmental Biology
subject: Science Policy
subject: Computational Biology

description: The plastic deformation of nanocrystalline Ag, with columnar grains, has been studied by molecular dynamics simulations. The nanocrystalline systems show two types of deformation mechanisms. One is the split of grain boundary that occurs before the activation of the dislocation in nanocrystalline Ag, and almost no dislocation debris and twins are left in the grains. Moreover, split of grain boundary is shown between the grains of nanocrystalline Ag. Another mechanism consists in partial dislocations dominating the process of plastic deformation. Plenty of stacking faults and twins remain in the grains of nanocrystalline Ag. It is revealed that different grain aspect ratios have induced the difference in deformation mechanisms of nanocrystalline Ag. When the grain aspect ratio is less than or equal to 1, the process of plastic deformation is dominated by partial dislocations. Otherwise, the process is dominated by split of grain boundary. The grain aspect ratio is the height in z direction to length in x direction ratio, which was found to noticeably impact yield strength, grain coarsening, indicating that the observed behaviour should have contributed to the plastic deformation significantly.
Additional file 1 of Dual-functional alginate and collagen–based injectable hydrogel for the treatment of cancer and its metastasis
Creators: name: Hwang, Juyoung
name: An, Eun-Koung
name: Zhang, Wei
name: Kim, Hyo Jeong
name: Eom, Youngho
name: Jin, Jun-O.
Publisher: name: figshare
Year: 2022
Subjects: subject: Immunology
subject: FOS: Clinical medicine

description: Additional file 1: Figure S1. Thermographic images of CT-26 tumor-bearing mice intratumorally injected with PBS, poly I:C, Gel, pGel, TRG, and pTRG and then exposed to an 808-nm laser at a power density of 1.5 W/cm2 for 5 min (n = 6). Figure S2. Schematic illustration of the treatment strategy and the first and second tumor challenge models. Figure S3. Thermal images of 4T1 tumor-bearing mice intratumorally treated with PBS, poly I:C, Gel, TRG, and pTRG (left panel) and the average temperature after 808-nm laser irradiation (right panel, n = 6, **p < 0.01). Figure S4. Cumulative release of the stimulator of interferon genes ligand (STING L), anti-PD-1 antibody (α-PD-1), and the anti-PD-L1 antibody (α-PD-L1) from TRGs after 808-nm laser irradiation (1.5 W/cm2, 5 min). Figure S5. Thermal images of CT-26 tumor-bearing mice irradiated with 808-nm laser (1.5 W/cm2, 5 min) after an i.t. injection of TRGs incorporated with poly I:C, stimulator of interferon genes ligand (STING L), anti-PD-1 antibody (α-PD-1), or anti-PD-L1 antibody (α-PD-L1). Figure S6. Measurement of antibody activity after NIR irradiation in TRG. Anti-PD-1 and anti-PD-L1 antibodies were harvested from TRGs after NIR irradiation (1.5 W/cm2, 5 min). (A) Isolated CD3+ T cells were incubated with the released (A) anti-PD-1 antibodies and (B) anti-PD-L1 antibodies for 15 min, followed by secondary antibody (anti-goat-APC) staining for the evaluation of the functional activity of the released antibodies. Figure S7. Treatment with immune-stimulatory molecules failed to inhibit tumor growth. The CT-26 cells were injected into BALB/C mice as shown in Figure 7A. Indicated immune-stimulatory molecules containing TRGs were injected i.t. 7 days after tumor injection. (A) The representative tumor masses are shown 24 days after tumor injection. (B) CT-26 mouse tumor growth curves (n = 6).
Feasibility of binary composition in development of nanoethosomal glycolic vesicles of triamcinolone acetonide using Box-behnken design: in vitro and ex vivo characterization
Creators: name: Akhtar, Nida
name: Anurag Verma
name: Pathak, Kamla
Publisher: name: Taylor & Francis
Year: 2016
Subjects: subject: Biophysics
subject: Biochemistry
subject: Space Science
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Pharmacology
subject: Biotechnology
subject: 39999 Chemical Sciences not elsewhere classified
subject: FOS: Chemical sciences
subject: 69999 Biological Sciences not elsewhere classified
subject: FOS: Biological sciences
subject: Developmental Biology

description: Triamcinolone acetonide (TA) employed for the treatment of atopic dermatitis exhibits limited penetration into the epidermis. This investigation aimed to explore the role of binary solvents in topical drug delivery of TA by developing nanoethosomal glycolic lipid vesicles by infusion method. Screening of vesicles (TA1-TA17) formulated by Box Behnken design identified the optimized formulation (TA10) that was developed as carbomer gels. The gels were then evaluated for pharmaceutical properties and compared with control and reference ethosomal gel (RG). Higher in vitro permeation was found in gels containing TA10, prepared with or without using penetration enhancer (EGP 83.76 ± 0.72% and EG 82.42 ± 0.89%, respectively). CLSM studies depicted deeper uniform penetration of fluorescent tracer into the epidermis via EG as compared with RG and control gel. Enhanced penetration was due to combinational solvent effect exerted by ethanol and propylene glycol. Histological analysis confirmed the non-irritant potential of the gel. Thus, it can be concluded that nanoethosomal glycolic vesicles proved to be an effective non irritant carrier for improvised penetration of triamcinolone acetonide for potential topical therapeutics.
Splitting theorems for Finsler manifolds of nonnegative Ricci curvature
Creators: name: Ohta, Shin-ichi
Publisher: name: arXiv
Year: 2012
Subjects: subject: Differential Geometry (math.DG)
subject: FOS: Mathematics

description: We investigate the structure of a Finsler manifold of nonnegative weighted Ricci curvature including a straight line, and extend the classical Cheeger-Gromoll-Lichnerowicz splitting theorem. Such a space admits a diffeomorphic, measure-preserving splitting in general. As for a special class of Berwald spaces, we can perform the isometric splitting in the sense that there is a one-parameter family of isometries generated from the gradient vector field of the Busemann function. A Betti number estimate is also given for Berwald spaces.
description: 21 pages; minor corrections; to appear in J. Reine Angew. Math
Riedl et al Supporting Figure SF5 (figshare)
Creators: name: Riedl, Angelika
name: Dolznig, Helmut
Publisher: name: figshare
Year: 2016
Subjects: subject: 60802 Animal Cell and Molecular Biology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 60111 Signal Transduction

description: Western Blot analysis
Demystifying Benjamin Franklin's other 8-square
Creators: name: Ahmed, Maya Mohsin
Publisher: name: arXiv
Year: 2015
Subjects: subject: History and Overview (math.HO)
subject: FOS: Mathematics

description: In this article, we reveal how Benjamin Franklin constructed his second $8 \times 8$ magic square. We also construct two new $8 \times 8$ Franklin squares.
Additional file 1 of Construction of liquid metal-based soft microfluidic sensors via soft lithography
Creators: name: Zhang, Yang
name: Duan, Haowei
name: Li, Guoqiang
name: Peng, Maoyu
name: Ma, Xing
name: Li, Ming
name: Yan, Sheng
Publisher: name: figshare
Year: 2022
Subjects: Space Science
Physical Sciences not elsewhere classified
Medicine
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified

description: Additional file 1: Figure S1. The mechanism of the spreading of LM on the Cu surface. Figure S2. Contact angles on adhesive sheet and masked copper tape. Figure S3. The effect of height of channels on LM patterning process. Figure S4. A repeatability test of self-powering sensor. Figure S5. CVs of GOx/AuNPs/MXene modified liquid metal electrode at different scan rates: 10 to 300 mV/s. S1. Discussion about the feature size limitation. S2. The applied pressure in pressing and tensile tests. S3. The comparison of PDMS and Ecoflex in fabricating performance.
title: 01_0176
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
A study on refractive index sensors based on optical micro-ring resonators
Creators: name: Tsigaridas, Georgios N.
Publisher: name: arXiv
Year: 2015
Subjects: subject: Optics (physics.optics)
subject: FOS: Physical sciences

description: In this work the behavior of optical micro-ring resonators, especially when functioning as refractive index sensors, is studied in detail. Two configurations are considered, namely a linear waveguide coupled to a circular one and two linear waveguides coupled to each other through a circular one. The optimum coupling conditions are derived and it is shown that in both cases the condition for the resonant wavelength, i.e. the wavelength at which the transmission spectrum exhibits a dip (peak), is the same and depends only on the geometrical characteristics of the circular waveguide and the effective refractive index of the propagating mode. The latter, as well as the corresponding mode profile, can be easily calculated through numerical analysis. The sensitivity of the sensor is defined based on the dependence of the effective refractive index on the refractive index of the environment. Using a result of waveguide perturbation theory, the geometrical characteristics of the core of the circular waveguide that maximize the sensitivity of the system are determined. Both single and dual core configurations are considered. It is found that, when optimally designed, the sensor can detect relative refractive index changes of the order of 10^-4, assuming that the experimental setup can detect relative wavelength shifts of the order of 3x10^-5. Finally, the behavior of the system as bio-sensor is examined by considering that a thin layer of bio-material is attached on the surface of the waveguide core. It is found that, when optimally designed, the system can detect refractive index changes of the order of 10^-3 for a layer thickness of 10 nm, and changes in the layer thickness of the order of 0.24 nm, for a refractive index change of 0.05.
Some functional inequalities on non-reversible Finsler manifolds
Creators: name: Ohta, Shin-ichi
Publisher: name: arXiv
Year: 2017
Subjects: subject: Differential Geometry (math.DG)
subject: Analysis of PDEs (math.AP)
subject: FOS: Mathematics

description: We continue our study of geometric analysis on (possibly non-reversible) Finsler manifolds, based on the Bochner inequality established by the author and Sturm. Following the approach of the $Γ$-calculus a la Bakry et al, we show the dimensional versions of the Poincare--Lichnerowicz inequality, the logarithmic Sobolev inequality, and the Sobolev inequality. In the reversible case, these inequalities were obtained by Cavalletti--Mondino in the framework of curvature-dimension condition by means of the localization method. We show that the same (sharp) estimates hold also for non-reversible metrics.
description: 22 pages (no change from v3); Corrigendum is available at http://www4.math.sci.osaka-u.ac.jp/~sohta/ ; See also my book "Comparison Finsler geometry" https://link.springer.com/book/10.1007/978-3-030-80650-7
Riedl et al Supporting Figure SF4 (figshare)
Creators: name: Dolznig, Helmut
Publisher: name: figshare
Year: 2016
Subjects: subject: 60802 Animal Cell and Molecular Biology
subject: FOS: Biological sciences
subject: Cell Biology
subject: 60111 Signal Transduction

description: Western Blot analysis
An adaptive reduced basis collocation method based on PCM ANOVA decomposition for anisotropic stochastic PDEs
Creators: name: Cho, Heyrim
name: Elman, Howard C.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Numerical Analysis (math.NA)
subject: FOS: Mathematics
subject: G.1.0
subject: 60H15, 60H35, 65N35

description: The combination of reduced basis and collocation methods enables efficient and accurate evaluation of the solutions to parameterized PDEs. In this paper, we study the stochastic collocation methods that can be combined with reduced basis methods to solve high-dimensional parameterized stochastic PDEs. We also propose an adaptive algorithm using a probabilistic collocation method (PCM) and ANOVA decomposition. This procedure involves two stages. First, the method employs an ANOVA decomposition to identify the effective dimensions, i.e., subspaces of the parameter space in which the contributions to the solution are larger, and sort the reduced basis solution in a descending order of error. Then, the adaptive search refines the parametric space by increasing the order of polynomials until the algorithm is terminated by a saturation constraint. We demonstrate the effectiveness of the proposed algorithm for solving a stationary stochastic convection-diffusion equation, a benchmark problem chosen because solutions contain steep boundary layers and anisotropic features. We show that two stages of adaptivity are critical in a benchmark problem with anisotropic stochasticity.
Additional file 1 of Elaborate design of shell component for manipulating the sustained release behavior from core–shell nanofibres
Creators: name: Liu, Yubo
name: Chen, Xiaohong
name: Gao, Yuhang
name: Yu, Deng-Guang
name: Liu, Ping
Publisher: name: figshare
Year: 2022
Subjects: subject: Space Science
subject: Medicine
subject: Physiology
subject: FOS: Biological sciences
subject: Pharmacology
subject: Biotechnology
subject: Chemical Sciences not elsewhere classified
subject: Biological Sciences not elsewhere classified

description: Additional file 1: Figure S1. Digital pictures of the modified coaxial electrospinning process of F1 monothetic fibres. Figure S2. The XRD pattern of different content of drugs in monothetic fibres. Figure S3. The surface wetting performance of different additives in CA monothetic fibres. Figure S4. SEM images of CA monothetic fibres containing hydrophilic additives before and after moisture immersion. Figure S5. The surface wetting performance of CA monothetic fibres containing 3% PEG a and 1% PEG. Figure S6. The dynamic surface wetting results of F1 fibres. Figure S7. Digital pictures of initial dry F1 (a), initial dry F2 (b), wet F1 (c), and wet F2 (d). Figure S8. Pictures of aluminum foil after the removal of F1 (a), F2 (b), F3 (c), and F4 (d) fibres.
On the virtual singular braid monoid
Creators: name: Caprau, Carmen
name: Zepeda, Sarah
Publisher: name: arXiv
Year: 2017
Subjects: subject: Geometric Topology (math.GT)
subject: FOS: Mathematics
subject: 57M25, 57M27, 20F36

description: We study the algebraic structures of the virtual singular braid monoid, $VSB_n$, and the virtual singular pure braid monoid, $VSP_n$. The monoid $VSB_n$ is the splittable extension of $VSP_n$ by the symmetric group $S_n$. We also construct a representation of $VSB_n$.
description: 21 pages, 4 figures
Riedl et al Supporting Figure SF3 (figshare)
Creators: name: Riedl, Angelika
name: Dolznig, Helmut
Publisher: name: figshare
Year: 2016
Subjects: subject: 60802 Animal Cell and Molecular Biology
subject: FOS: Biological sciences
subject: Cell Biology
subject: Molecular Biology
subject: 60111 Signal Transduction

description: Cleaved caspase 3 IF in DLD-1 cells in 2D and 3D
Measuring Quantum Entropy
Creators: name: Acharya, Jayadev
name: Issa, Ibrahim
name: Shende, Nirmal V.
name: Wagner, Aaron B.
Publisher: name: arXiv
Year: 2017
Subjects: subject: Quantum Physics (quant-ph)
subject: Data Structures and Algorithms (cs.DS)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: The entropy of a quantum system is a measure of its randomness, and has applications in measuring quantum entanglement. We study the problem of measuring the von Neumann entropy, $S(ρ)$, and Rényi entropy, $S_α(ρ)$ of an unknown mixed quantum state $ρ$ in $d$ dimensions, given access to independent copies of $ρ$. We provide an algorithm with copy complexity $O(d^{2/α})$ for estimating $S_α(ρ)$ for $α<1$, and copy complexity $O(d^{2})$ for estimating $S(ρ)$, and $S_α(ρ)$ for non-integral $α>1$. These bounds are at least quadratic in $d$, which is the order dependence on the number of copies required for learning the entire state $ρ$. For integral $α>1$, on the other hand, we provide an algorithm for estimating $S_α(ρ)$ with a sub-quadratic copy complexity of $O(d^{2-2/α})$. We characterize the copy complexity for integral $α>1$ up to constant factors by providing matching lower bounds. For other values of $α$, and the von Neumann entropy, we show lower bounds on the algorithm that achieves the upper bound. This shows that we either need new algorithms for better upper bounds, or better lower bounds to tighten the results. For non-integral $α$, and the von Neumann entropy, we consider the well known Empirical Young Diagram (EYD) algorithm, which is the analogue of empirical plug-in estimator in classical distribution estimation. As a corollary, we strengthen a lower bound on the copy complexity of the EYD algorithm for learning the maximally mixed state by showing that the lower bound holds with exponential probability (which was previously known to hold with a constant probability). For integral $α>1$, we provide new concentration results of certain polynomials that arise in Kerov algebra of Young diagrams.
Packing degenerate graphs
Creators: name: Allen, Peter
name: Böttcher, Julia
name: Hladký, Jan
name: Piguet, Diana
Publisher: name: arXiv
Year: 2017
Subjects: subject: Combinatorics (math.CO)
subject: FOS: Mathematics

description: Given $D$ and $γ>0$, whenever $c>0$ is sufficiently small and $n$ sufficiently large, if $\mathcal{G}$ is a family of $D$-degenerate graphs of individual orders at most $n$, maximum degrees at most $\tfrac{cn}{\log n}$, and total number of edges at most $(1-γ)\binom{n}{2}$, then $\mathcal{G}$ packs into the complete graph $K_{n}$. Our proof proceeds by analysing a natural random greedy packing algorithm. This version of the manuscript corrects a small error that appeared in the published version [Adv Math, 354 (2019), 106739].
description: 48 pages. This version corrects small errors that we found after the publication in Adv Math. More details in Section 1.1
A low phase noise microwave frequency synthesizer based on parameters optimized NLTL for Cs fountain clock
Creators: name: Li, Wenbing
name: Du, Yuanbo
name: Li, Hui
name: Lu, Zehuang
Publisher: name: arXiv
Year: 2018
Subjects: subject: Atomic Physics (physics.atom-ph)
subject: FOS: Physical sciences

description: We report on the development and phase noise performance of a 9.1926 GHz microwave frequency synthesizer to be used as the local oscillator for a Cs fountain clock. It is based on frequency multiplication and synthesis from an ultralow phase noise 5 MHz Oven Controlled Crystal Oscillator (OCXO) and 100 MHz Voltage Controlled Crystal Oscillator (VCXO).The key component of the frequency multiplication is a non-linear transmission-line (NLTL) used as a frequency comb generator. The phase noise of the synthesizer is improved by carefully optimizing the input power, the input and output impedances of the NLTL. The absolute phase noises of the 9.1926 GHz output signal are measured to be -64 dBc/Hz, -83 dBc/Hz, -92 dBc/Hz, -117 dBc/Hz and -119 dBc/Hz at 1 Hz, 10Hz, 100Hz, 1 kHz and 10 kHz offset frequencies, respectively. The residual phase noise of the synthesizer is measured to be -82 dBc/Hz at 1 Hz offset frequency. The measurement result shows that the absolute phase noise at the frequency range of 1 - 100 Hz is mainly limited by the phase noise of the OCXO. The contribution of the absolute phase noise to the fountain clock short-term frequency stability is calculated to be 7.0x10^(-14). The residual frequency stability of the synthesizer is measured to be1.5x10^(-14), which is consistent with the calculated frequency stability due to the residual phase noise of the synthesizer. Meanwhile we designed and realized an interferometric microwave switch in the synthesizer to eliminate the frequency shifts induced by the microwave leakage. The extinction ratio of the switch is measured to be more than 50 dB. In the scheme, we use only commercially available components to build the microwave frequency synthesizer with excellent phase noise performance for high-performance Cs fountain clocks.
Generalized nil-Coxeter algebras
Creators: name: Khare, Apoorva
Publisher: name: arXiv
Year: 2018
Subjects: subject: Rings and Algebras (math.RA)
subject: Combinatorics (math.CO)
subject: Group Theory (math.GR)
subject: Representation Theory (math.RT)
subject: FOS: Mathematics
subject: 20F55 (Primary), 20F05, 20C08 (Secondary)

description: Motivated by work of Coxeter (1957), we study a class of algebras associated to Coxeter groups, which we term 'generalized nil-Coxeter algebras'. We construct the first finite-dimensional examples other than usual nil-Coxeter algebras; these form a $2$-parameter type $A$ family that we term $NC_A(n,d)$. We explore the combinatorial properties of these algebras, including the Coxeter word basis, length function, maximal words, and their connection to Khovanov's categorification of the Weyl algebra. Our broader motivation arises from complex reflection groups and the Broue-Malle-Rouquier freeness conjecture (1998). With generic Hecke algebras over real and complex groups in mind, we show that the 'first' finite-dimensional examples $NC_A(n,d)$ are in fact the only ones, outside of the usual nil-Coxeter algebras. The proofs use a diagrammatic calculus akin to crystal theory.
description: 12 pages, final version. This is an extended abstract of arXiv:1601.08231, accepted in FPSAC 2018
MeetSense: A Lightweight Framework for Group Identification using Smartphones
Creators: name: Das, Snigdha
name: Chatterjee, Soumyajit
name: Chakraborty, Sandip
name: Mitra, Bivas
Publisher: name: arXiv
Year: 2018
Subjects: subject: Social and Information Networks (cs.SI)
subject: Sound (cs.SD)
subject: Audio and Speech Processing (eess.AS)
subject: FOS: Computer and information sciences
subject: FOS: Electrical engineering, electronic engineering, information engineering

description: In an organization, individuals prefer to form various formal and informal groups for mutual interactions. Therefore, ubiquitous identification of such groups and understanding their dynamics are important to monitor activities, behaviours and well-being of the individuals. In this paper, we develop a lightweight, yet near-accurate, methodology, called MeetSense, to identify various interacting groups based on collective sensing through users' smartphones. Group detection from sensor signals is not straightforward because users in proximity may not always be under the same group. Therefore, we use acoustic context extracted from audio signals to infer interaction pattern among the subjects in proximity. We have developed an unsupervised and lightweight mechanism for user group detection by taking cues from network science and measuring the cohesivity of the detected groups in terms of modularity. Taking modularity into consideration, MeetSense can efficiently eliminate incorrect groups, as well as adapt the mechanism depending on the role played by the proximity and the acoustic context in a specific scenario. The proposed method has been implemented and tested under many real-life scenarios in an academic institute environment, and we observe that MeetSense can identify user groups with close to 90% accuracy even in a noisy environment.