cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
A complex and punctate distribution of three eukaryotic genes derived by lateral gene transfer
Creators: name: Rogers, Matthew B.
name: Watkins, Russell F.
name: Harper, James T.
name: Durnford, Dion G.
name: Gray, Michael W.
name: Keeling, Patrick J. (Patrick John), 1969-
Publisher: name: BioMed Central
Year: 2016

description: Background: Lateral gene transfer is increasingly invoked to explain phylogenetic results that conflict with our understanding of organismal relationships. In eukaryotes, the most common observation interpreted in this way is the appearance of a bacterial gene (one that is not clearly derived from the mitochondrion or plastid) in a eukaryotic nuclear genome. Ideally such an observation would involve a single eukaryote or a small group of related eukaryotes encoding a gene from a specific bacterial lineage. Results: Here we show that several apparently simple cases of lateral transfer are actually more complex than they originally appeared: in these instances we find that two or more distantly related eukaryotic groups share the same bacterial gene, resulting in a punctate distribution. Specifically, we describe phylogenies of three core carbon metabolic enzymes: transketolase, glyceraldehyde-3-phosphate dehydrogenase and ribulose-5-phosphate-3-epimerase. Phylogenetic trees of each of these enzymes includes a strongly-supported clade consisting of several eukaryotes that are distantly related at the organismal level, but whose enzymes are apparently all derived from the same lateral transfer. With less sampling any one of these examples would appear to be a simple case of bacterium-to-eukaryote lateral transfer; taken together, their evolutionary histories cannot be so simple. The distributions of these genes may represent ancient paralogy events or genes that have been transferred from bacteria to an ancient ancestor of the eukaryotes that retain them. They may alternatively have been transferred laterally from a bacterium to a single eukaryotic lineage and subsequently transferred between distantly related eukaryotes. Conclusion: Determining how complex the distribution of a transferred gene is depends on the sampling available. These results show that seemingly simple cases may be revealed to be more complex with greater sampling, suggesting many bacterial genes found in eukaryotic genomes may have a punctate distribution.
Die deutschsprachige Forschung zur Transformation politischer Systeme in Asien – Perspektiven, Profile und Befunde
Creators: name: Croissant, Aurel
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: German scholars have long neglected the analysis of political transformation pro-cesses in South, Southeast, and Northeast Asia. Only since the end of the 1990s have researchers in Germany developed an interest in this international, mostly English-language, literature. In contrast, German-language political science democ-ratization research on Asia has long been well established. As in North America, the boundaries between democratization and autocracy research have become blurred in recent years — while the close link between democracy and dictatorship research is a welcome development. Theoretically and methodologically, the German-language transformation research on Asia has made only a comparatively small contribution to international political science research. Its main advance has been in its in-depth analysis of individual or select cases. In order to remain internationally pertinent and to become more widely accepted, German-language research hence-forth needs to be more methodologically nuanced as well as to embrace the triangulation of data and mixed-methods research designs.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
Smart Citizen Platform Technical Documentation
Creators: name: Camprodon, Guillem
name: Aloa, Aitor
name: Gonzalez, Oscar
name: Barberan, Victor
name: Muñoz, Angel
name: Smári, Viktor
name: Hijden, Pieter Van Der
name: Cordero, Ben
Publisher: name: Zenodo
Year: 2019

description: Smart Citizen Documentation
Signaling pathways employed by thyroid stimulating hormone to induce interleukin-6 release from human and 3T3-L1 adipocytes
Creators: name: Antunes, Tayze Tatiana
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2009
Subjects: subject: Chemistry, Biochemistry.

description: Subclinical hypothyroidism, a condition characterized by elevated thyroid stimulating hormone (TSH) levels, is a risk factor for cardiovascular disease (CVD). Adipose tissue contributes significantly to the circulating levels of interleukin-6 (IL-6), an atherogenic and pro-inflammatory cytokine. Adipose cells express TSH receptors and are responsive to TSH. The overall hypothesis of my Ph.D. project is that TSH acts on adipose cells to stimulate the release of IL-6. In this thesis, I studied TSH-induced IL-6 release and the related signaling mechanisms using the mouse 3T3-Ll adipose cell line. I also evaluated human primary adipose cells, and examined the influence of stage of differentiation and fat depot localization on the effect of TSH on IL-6 release. I first showed that in 3T3-Ll cells, TSH induces IL-6 release from differentiated adipocytes, but not from precursor cells (preadipocytes). Differentiated 3T3-Ll adipocytes increased IL-6 release in response to TSH via activation of the cAMP-dependent protein kinase (PKA) pathway. Following analysis of the TSH effect on 3T3-Ll adipose cell line, I proceeded to examine the effect of TSH on human primary adipose cells. For the abdominal subcutaneous depot, I found that preadipocytes did not release IL-6 in response to TSH, but their differentiated adipocytes counterparts were TSH-responsive. In contrast, for the omental depot, I showed that neither preadipocytes nor the differentiated adipocytes increased IL-6 release in response to TSH. Signaling studies on the human abdominal subcutaneous differentiated adipocytes revealed that TSH activates the nuclear factor kappa-B pathway to induce IL-6 release. Furthermore, PKA activation by TSH does not result in increased NF-kappaB signaling. To demonstrate that TSH could act in an extra-thyroidal fashion in vivo, I analyzed serum IL-6levels in thyroidectomized patients with a past history of thyroid cancer undergoing recombinant human (rh)TSH administration. Injection with rhTSH increased IL-6 serum levels, supporting the notion that TSH has extra-thyroidal actions in vivo. In summary, this thesis demonstrates that TSH is capable of regulating inflammatory responses on adipose cells and of elevating IL-6, a biomarker of inflammation, in the circulation of thyroidectomized patients.
Priority setting in the provincial health services authority: survey of key decision makers
Creators: name: Teng, Flora
name: Mitton, Craig, 1972-
name: MacKenzie, Jennifer
Publisher: name: BioMed Central
Year: 2015

description: Background: In recent years, decision makers in Canada and elsewhere have expressed a desire for more explicit, evidence-based approaches to priority setting. To achieve this aim within health care organizations, knowledge of both the organizational context and stakeholder attitudes towards priority setting are required. The current work adds to a limited yet growing body of international literature describing priority setting practices in health organizations. Methods A qualitative study was conducted using in-depth, face-to-face interviews with 25 key decision makers of the Provincial Health Services Authority (PHSA) of British Columbia. Major themes and sub-themes were identified through content analysis. Results Priorities were described by decision makers as being set in an ad hoc manner, with resources generally allocated along historical lines. Participants identified the Strategic Plan and a strong research base as strengths of the organization. The main areas for improvement were a desire to have a more transparent process for priority setting, a need to develop a culture which supports explicit priority setting, and a focus on fairness in decision making. Barriers to an explicit allocation process included the challenge of providing specialized services for disparate patient groups, and a lack of formal training in priority setting amongst decision makers. Conclusion This study identified factors important to understanding organizational context and informed next steps for explicit priority setting for a provincial health authority. While the PHSA is unique in its organizational structure in Canada, lessons about priority setting should be transferable to other contexts.
Soziologische Chinastudien und chinesische Soziologie im globalen Kontext
Creators: name: Gransow, Bettina
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: Sociological China studies are normally thought of as part of Western social sciences/area studies, whereas Chinese sociology is associated with sociology in China. What both have in common is Chinese society as their research focus, while the country’s ongoing rapid social change provides an abundant variety of social issues and challenges to work on. In addition, with China’s increasing global presence, there is an ever greater need for deeper understanding of the country’s global interrelations and social influences beyond its domestic borders. Taking the German Association for Social Science Research on China as its starting point, this paper explores whether and how sociological China research and Chinese sociology are becoming parts of an emerging cosmopolitan/global sociology existing beyond the methodological nationalism of classical sociology. It argues that the emerging field of global sociology is characterized by the fragmented and asymmetric production and diffusion of sociological knowledge, and that sociological China studies and Chinese sociology are entering this field from different angles — while also being embedded in different national political, academic, and funding frameworks. Drawing on Michael Burawoy’s typology of the production of sociological knowledge as a contradictory yet complementary division of professional, policy, critical, and public Sociology, the paper further argues in favor of strengthening the reflexive production of sociological knowledge on China (meaning critical and public sociology) that seeks to elaborate on its critical foundations and to find its academic and extra-academic audiences. At the same time, this might also provide common ground for sociological China studies and Chinese sociology within the currently asymmetrical emerging field of global sociology.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
ЎТКИР РЕСПИРАТОР ВИРУСЛИ ИНФЕКЦИЯДА КРУП СИНДРОМИНИ ҲОЗИРГИ ЗАМОН ДАВОЛАШ АСПЕКТЛАРИ
Creators: name: Кудратова, Гулсара
Publisher: name: Zenodo
Year: 2024

description: Болаларда ўткир респиратор вирусли инфекция фонида юқори нафас олиш йўлларининг торайиш ҳолати кўп учрайди ва кўп патологик ҳолатлар кўринишида намоён бўлади, шулардан бири круп синдромидир.
Zivilgesellschaft in Japan: Schlaglichter auf ein bewegtes Forschungsfeld
Creators: name: Wiemann, Anna
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: Since the 1980s the study of civil society in Japan has gained in popularity among social scientists both in Europe and in the United States. Two ideas regarding the character of Japanese civil society prevail: The first is a postulated weakness of Japanese civil society, caused by a high number of small, informal groups alongside only a limited number professional ones — as well as difficult access to policymaking. The second idea is that Japanese civil society represents a vivid alternative political sphere, being particularly rich in social capital. This research note presents these arguments in their wider context, and highlights important changes in the orientation of research on civil society in Japan in relation to social and political developments occurring over time.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
Taiwanstudien und -forschung in Deutschland
Creators: name: Damm, Jens
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: This article examines Taiwan studies and research in Germany from a historical perspective, while simultaneously taking into account the current situation too. The first question asked is how these issues can be explained without falling into the trap of locating the current understanding of Taiwan back in the past, this being an error that occurs far too often in presentations from both the Western and the Taiwanese points of view. Taking into account the fact that Taiwan, or the Republic of China on Taiwan, is a de facto independent state that is not recognized internationally as a result of the dominance of the “One-China Policy,” this paper points out that a not insignificant part of today’s Taiwan research — especially in the political or general social sciences — is concerned with the unique situation of the island-state, and that this includes research on the special relationship between Taiwan and China. The main focus is on the period after the 1990s, because since that time Taiwan has become an interesting research subject. Taiwan’s relationship with China is a matter of hot dispute, with some voices claiming that research on the island-state should move away from a Chinese perspective — while others regard Taiwan as a model that offers an interesting alternative to developments in the People’s Republic of China.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
Large-scale copy number variants (CNVs): Distribution in normal subjects and FISH/real-time qPCR analysis
Creators: name: Qiao, Ying
name: Liu, Xudong
name: Harvard, Chansonette
name: Nolin, Sarah L
name: Brown, W T
name: Koochek, Maryam
name: Holden, Jeanette J
name: Lewis, ME S
name: Rajcan-Separovic, Evica
Publisher: name: BioMed Central
Year: 2016

description: Background: Genomic copy number variants (CNVs) involving >1 kb of DNA have recently been found to be widely distributed throughout the human genome. They represent a newly recognized form of DNA variation in normal populations, discovered through screening of the human genome using high-throughput and high resolution methods such as array comparative genomic hybridization (array-CGH). In order to understand their potential significance and to facilitate interpretation of array-CGH findings in constitutional disorders and cancers, we studied 27 normal individuals (9 Caucasian; 9 African American; 9 Hispanic) using commercially available 1 Mb resolution BAC array (Spectral Genomics). A selection of CNVs was further analyzed by FISH and real-time quantitative PCR (RT-qPCR). Results: A total of 42 different CNVs were detected in 27 normal subjects. Sixteen (38%) were not previously reported. Thirteen of the 42 CNVs (31%) contained 28 genes listed in OMIM. FISH analysis of 6 CNVs (4 previously reported and 2 novel CNVs) in normal subjects resulted in the confirmation of copy number changes for 1 of 2 novel CNVs and 2 of 4 known CNVs. Three CNVs tested by FISH were further validated by RT-qPCR and comparable data were obtained. This included the lack of copy number change by both RT-qPCR and FISH for clone RP11-100C24, one of the most common known copy number variants, as well as confirmation of deletions for clones RP11-89M16 and RP5-1011O17. Conclusion: We have described 16 novel CNVs in 27 individuals. Further study of a small selection of CNVs indicated concordant and discordant array vs. FISH/RT-qPCR results. Although a large number of CNVs has been reported to date, quantification using independent methods and detailed cellular and/or molecular assessment has been performed on a very small number of CNVs. This information is, however, very much needed as it is currently common practice to consider CNVs reported in normal subjects as benign changes when detected in individuals affected with a variety of developmental disorders.
Prehistoric Human-Environment Interaction in Eastern North America
Creators: name: Munoz, Samuel E
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Anthropology, Archaeology.
subject: Geography.
subject: Paleoecology.

description: Industrialized human societies both affect and are vulnerable to environmental change, but the dynamics of human-environment relationships during prehistory are less well understood. Using large databases of accumulated paleoecological and archaeological records, this dissertation explores the relationship between prehistoric humans and environmental change in eastern North America. A synthesis of late Quaternary paleoecological and archaeological data from the northeastern United States shows a close temporal correspondence between changes in climate, terrestrial ecosystems, human culture and population numbers. These synchronous changes occurred at 11.6, 8.2, 5.4 and 3.0 thousand years before present, before the adoption of maize agriculture when human groups in eastern North America subsisted by hunting and gathering. Further examination of these datasets in southern Ontario over the last two thousand years found that clearance of forests by prehistoric Native Americans for agricultural fields significantly altered terrestrial ecosystems at a sub-regional scale (102-10 3 m). Together, these results support the hypothesis that prehistoric Native Americans had a greater environmental impact than previously believed, but show that this impact was concentrated around agricultural settlements and was less substantial than that associated with European settlement during the historic period. The methodologies developed in this dissertation provide a means to better understand human-environment relationships in other regions which differ in their environmental and cultural histories.
Koreaforschung in Deutschland – Geschichtlicher Überblick und Perspektiven
Creators: name: Lee, Eun-Jeung
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: In German academia, Korean Studies still counts among the so-called “small subjects.” Only a handful of universities even offer degrees in Korean Studies. While Korean Studies has long been associated with the Humanities, especially Linguistics and Literature, it is now increasingly oriented toward the Social Sciences. With the absolute number of those focusing their research on Korea being only very small, the range of research topics in German Korean Studies is still fairly limited when compared to Sinology or Japanese Studies, to give just two examples. Put positively, Korean Studies in Germany has considerable potential to widen its ambit and to freshly explore a vast range of interesting and meaningful topics.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
Die Vietnamistik an der Universität Hamburg
Creators: name: Engelbert, Thomas
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: Vietnamese Studies are about the language and culture of the Vietnamese people. This academic subject first originated in France in the 19th century. In the 20th century, the United States and Eastern Europe became new centres of Vietnamese Studies research. Nowadays, it is the country’s Asian neighbours who are developing this academic field more extensively. However in all countries it has continued to remain only a “small subject.” At the moment, indeed, the University of Hamburg is the only place where Vietnamese Studies can be pursued in the whole of Germany.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
Changes in the Arctic Oscillation under increased atmospheric greenhouse gases
Creators: name: Boer, George J.
name: Hsieh, William W.
name: Wu, Aiming
name: Zwiers, Francis W.
Publisher: name: American Geophysical Union
Year: 2016

description: The Arctic Oscillation (AO) under increased atmospheric concentration of greenhouse gases (GHG) was studied by comparing an ensemble of simulations from 13 coupled general circulation models with GHG at the pre-industrial level and at the late 20th century level, for November to March. The change in the linear AO pattern as GHG increased reveals positive sea level pressure (SLP) anomalies centered over the Gulf of Alaska, and weaker negative SLP anomalies over eastern Canada and North Atlantic – a pattern resembling the nonlinear AO pattern arising from a quadratic relation to the AO index. This quadratic AO pattern itself has positive SLP anomalies receding from Europe but strengthening over the Gulf of Alaska and surrounding areas as GHG increased. This study points to the importance of the nonlinear structure in determining how the linear oscillatory pattern changes when there is a change in the mean climate. An edited version of this paper was published by AGU. Copyright 2007 American Geophysical Union.
Collective storyboards through the lens of reverberations, computer-generated
Creators: name: Mallos, Melina
Publisher: name: The University of Melbourne
Year: 2024
Subjects: classificationCode: 390101
subject: Creative arts, media and communication curriculum and pedagogy
classificationCode: 390401
subject: Comparative and cross-cultural education
classificationCode: 470212
subject: Multicultural, intercultural and cross-cultural studies

description: An a/r/tographer desires to respond to metaphors and symbols in order to divulge what is known through what cannot be expressed in words alone. Artistic and textual experiences and understandings are embodied: in other words, symbols, metaphors, patterns, and concepts that keep repeating leverage new tensions and understandings. As I put all the storyboards together, the reverberations were ever present, niggling and prodding me to consider the knowing, doing, and making that were facilitated through this participatory research. These rhythms compel the viewer to consider each individual rendering again in a new light in order to confirm or challenge prior understandings.
Natural parameter values for generalized gene adjacency
Creators: name: Yang, Zhenyu
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Mathematics.

description: As genomes of related species diverge through rearrangement mutations, groups of genes once tightly clustered on a chromosome will tend to disperse to remote locations on this chromosome or even onto other chromosomes. Even if most rearrangements are local, e.g., small inversions or transpositions, after a long enough period of time their chromosomal locations may reflect little or none of their original proximity. Given the gene orders in two modern genomes, then, it may be difficult to decide if some set of genes are close enough in both genomes to infer some ancestral proximity or some functional relationship. There are a number of formal criteria for gene clustering in two or more organisms, giving rise to cluster detection algorithms and statistical tests for the significance of clusters. These methods all depend on one or more arbitrary parameters as well as n, the number of genes in common in the two genomes. The various parameters control, in different ways, the proximity of the genes on the chromosome in order to be considered a cluster. Change the parameters and the number of clusters may change, as may the content of each cluster. We explore a two-parameter class of gene proximity criteria, and find natural values for these parameters. One has to do with the parameter value where the expected information contained in two genomes about each other is maximized. The other has to do with parameter values beyond which all genes are clustered. We analyse these using combinatorial and probabilistic arguments as well as simulations.
Horizontal transfer of a eukaryotic plastid-targeted protein gene to cyanobacteria
Creators: name: Rogers, Matthew B.
name: Patron, Nicola J.
name: Keeling, Patrick J. (Patrick John), 1969-
Publisher: name: BioMed Central
Year: 2015

description: Background. Horizontal or lateral transfer of genetic material between distantly related prokaryotes has been shown to play a major role in the evolution of bacterial and archaeal genomes, but exchange of genes between prokaryotes and eukaryotes is not as well understood. In particular, gene flow from eukaryotes to prokaryotes is rarely documented with strong support, which is unusual since prokaryotic genomes appear to readily accept foreign genes. Results Here, we show that abundant marine cyanobacteria in the related genera Synechococcus and Prochlorococcus acquired a key Calvin cycle/glycolytic enzyme from a eukaryote. Two non-homologous forms of fructose bisphosphate aldolase (FBA) are characteristic of eukaryotes and prokaryotes respectively. However, a eukaryotic gene has been inserted immediately upstream of the ancestral prokaryotic gene in several strains (ecotypes) of Synechococcus and Prochlorococcus. In one lineage this new gene has replaced the ancestral gene altogether. The eukaryotic gene is most closely related to the plastid-targeted FBA from red algae. This eukaryotic-type FBA once replaced the plastid/cyanobacterial type in photosynthetic eukaryotes, hinting at a possible functional advantage in Calvin cycle reactions. The strains that now possess this eukaryotic FBA are scattered across the tree of Synechococcus and Prochlorococcus, perhaps because the gene has been transferred multiple times among cyanobacteria, or more likely because it has been selectively retained only in certain lineages. Conclusion A gene for plastid-targeted FBA has been transferred from red algae to cyanobacteria, where it has inserted itself beside its non-homologous, functional analogue. Its current distribution in Prochlorococcus and Synechococcus is punctate, suggesting a complex history since its introduction to this group.
JOGO INTERATIVO COMO ESTRATÉGIA PARA DISCUSSÃO DE QUESTÕES PSICOSSOCIAIS ENTRE ADOLESCENTES
Creators: name: Mendes, Ana Júlia Garcia
name: Lucas, Henrique Oliveira
name: de Jesus, Thais Ferreira
name: Liz, Rafael Gustavo de
Publisher: name: Zenodo
Year: 2025
Subjects: jogos
psicologia
adolescentes

description: O objetivo geral deste estudo é promover o desenvolvimento emocional e social de adolescentes através da aplicação de um jogo de tabuleiro, proporcionando espaço para reflexões e debates sobre questões relacionadas à saúde mental e ao cotidiano juvenil. Os objetivos específicos são identificar as principais vulnerabilidades dos adolescentes, avaliar a participação dos mesmos na dinâmica do jogo, estimular a compreensão e resolução de problemas cotidianos e promover o reconhecimento da importância da busca por suporte.
Perspectives for Economic Research on China
Creators: name: Fischer, Doris
Publisher: name: Asien
Year: 2021

description: China-related economic and business research constitutes a small but growing field of expertise outside China. The article discusses three key questions regarding the perspectives of economic and business research on China as an academic discipline in Germany. First, why is research on China's economy necessary and relevant? Second, how did the discipline emerge and develop? Third, what difficulties did and does the research focus face within German academic institutions? Against this background, the articles argues that a number of factors will most likely influence the future of the discipline: subsequent economic and political developments in China, Germany’s cooperation with educational and research institutions in China, and the impact of digitalization on economic research in general.
description: Asien, Nr. 144 (2017): ASIEN (Juli)
IN03224 Timbirivava Rock Inscription 2
Creators: name: Paranavitana, S.
Publisher: name: Zenodo
Year: 2020
Subjects: IN03224
UoC
Timbirivava

description: IN03224 Timbirivava Rock Inscription 2 - Transcript and Translation Source: Paranavitana, S. (1961). ‘Rock Inscriptions at Timbirivava and Andaragollava in the Vilpattu Sanctuary,’ University of Ceylon Review 19, no. 2, pp. 95–104. http://dlib.pdn.ac.lk/handle/123456789/1721
Neurochemical mechanisms involved in the anticipation, ingestion and termination of a meal: Focus on corticotropin-releasing hormone and bombesin-like peptides
Creators: name: McIntosh, Judith Frances
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2003
Subjects: subject: Psychology, Psychobiology.

description: The apparently simple decision to initiate or terminate a meal is extremely complex. However, the need to determine the physiological and psychological mechanisms regulating these processes has taken on an air of urgency due to escalating levels of eating disorders in our society. Ingestive patterns are influenced by a number of factors, including signaling circuits utilizing peptides, such as corticotropin-releasing hormone (CRH) and bombesin-like peptides (BN-LPs). As some of the peptidergic systems under study have also been implicated in the mediation of the stress response, some peptidergic linkages between 'stress' and 'satiety' responses are also explored. The overall objective of this thesis was to examine the pattern of utilization or release of BN-LPs and CRH at specific brain loci during (1) various phases of food ingestion, (2) the presentation of anticipatory cues paired with an appetitive event, and (3) exposure to stressors. Using in vivo microdialysis, we demonstrated that both CRH and BN-LPs are released from the central nucleus of the amygdala in response to both restraint stressor exposure and spontaneous food ingestion, an effect that was mirrored at the anterior pituitary. Furthermore, we demonstrated that CRH and BN-LPs were released at the medial prefrontal cortex in response to the "anticipation" of a palatable snack. These results raised the intriguing possibility that some aspects of both the feeding behavior and the organism's response to stressor exposure are being subserved by a common neurochemical mechanism(s). As such, it would be expected that variables that affect an organism's stress response would also have an impact on feeding behavior and related neurochemical processes. In fact we found that early life experience, gender and genetics variables (that appear to impact the stress response) also impact on the animal's neurochemical response(s) to ingestion as well as their propensity to consume a palatable snack. These experiments extend our current knowledge of the mechanism(s) underlying the control of food intake and support our contention that these systems may also serve to draw attention to events or cues of biological salience. Finally, these results also provide new insights into the potential mechanism(s) underlying various stress and eating dysfunctions, including anorexia nervosa, anorexia associated with AIDS, cancer, sickness or stress, bulimia nervosa, obesity and depression.
Extract from a MS. diary of Peter le Neve, Esq, Norroy king of arms, entitled Memoranda in Heraldry of such entries as relate to the county of Norfolk. (Part 1 on P23 - Part 3 on P369)
Creators: name: Carthew, G A
Publisher: name: Archaeology Data Service
Year: 2020

description: Norfolk Archaeology, 2 (1), 111-126
Die deutsche Südasienforschung im Wandel der Zeit
Creators: name: Brandt, Carmen
name: Hackenbroch, Kirsten
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: In 2006 the German Association for Asian Studies became host to the ongoing working group “Modern South Asia” (Arbeitskreis “Neuzeitliches Südasien”). This was the first such platform for scholars in Germany working on Modern South Asia that strived to link them beyond disciplinary boundaries. The reasons for this relatively late endeavor of interdisciplinary networking are manifold, and are discussed in depth in the article. Among other reasons, explanations are to be found in the particular history of institutionalized research on South Asia in Germany — meaning Indology. This discipline has been dominated by a focus on Old Indian languages, literatures, philosophies, and religions since its establishment at the beginning of the 19th century. Despite German scholars from other disciplines — mainly History and the Social Sciences — developing selective research projects related to modern South Asia from the mid-20th century onward, these new academic interests would barely lead to an institutionalization of Modern South Asian Studies. Only from the 1990s onward did this gradually change, with the economic liberalization of India, emerging trade relations between Germany and that country, the new geopolitical relevance of the region post-9/11, and overall increased media attention being given to the region in Germany. Accompanying these developments, a growing number of research groups in a variety of disciplines emerged to conduct research on a diverse range of current social, political, economic, or environmental phenomena in South Asia — developments manifested also by an enlarged number of South Asia-oriented funding initiatives. The transformation of research related to South Asia in recent years has thus brought out a new mode of interdisciplinary knowledge production, one driven particularly by young scholars.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
Oral infection of mice with Salmonella enterica serovar Typhimurium causes meningitis and infection of the brain
Creators: name: Wickham, Mark E.
name: Brown, Nat F.
name: Provias, John
name: Finlay, B. Brett, 1959-
name: Coombes, Brian K.
Publisher: name: BioMed Central
Year: 2015

description: Background. Salmonella meningitis is a rare and serious infection of the central nervous system following acute Salmonella enterica sepsis. For this pathogen, no appropriate model has been reported in which to examine infection kinetics and natural dissemination to the brain. Methods Five mouse lines including C57BL/6, Balb/c, 129S6-Slc11a1tm1 Mcg , 129S1/SvImJ, B6.129-Inpp5dtm1 Rkh were used in the murine typhoid model to examine the dissemination of systemic Salmonella enterica serovar Typhimurium following oral infection. Results We report data on spontaneous meningitis and brain infection following oral infection of mice with Salmonella enterica serovar Typhimurium. Conclusion This model may provide a system in which dissemination of bacteria through the central nervous system and the influence of host and bacterial genetics can be queried.
Microcrédit: Outil de développement pour les femmes de Goma en République Démocratique du Congo
Creators: name: Tambwe, Béatrice
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2010
Subjects: subject: Women's Studies.
subject: Economics, General.
subject: Sociology, Social Structure and Development.

description: Cette thèse accorde une place importante à la littérature sur le microcrédit qui a contribué dans le domaine du développement en fournissant des informations sur les femmes entrepreneures. Les expériences des femmes de Goma en République Démocratique du Congo affirment que le microcrédit est l'un des moyens par lequel elles peuvent atteindre leur empowerment socio-économique. Sur la base de quatre semaines de recherche à Goma, je vise à décrire l'implication de ces femmes dans les microcrédits afin de rendre compte de l'importance qu'elles accordent à des telles pratiques. L'objectif est d'explorer comment l'approche du microcrédit peut être interprétée comme un outil de réduction de la pauvreté. Évidemment, elles sont attirées à faire des petits commerces afin de subvenir aux besoins quotidiens de leurs familles. Ceci contribuera à comprendre cette approche comme un moyen par lequel les femmes trouvent leur propre place dans le développement.
Case Study: Bioeconomy, innovation and achieving climate neutrality in the rural economy
Creators: name: LOBA - Customer Experience Design
name: University of Bologna
name: Q PLAN International (Greece)
name: FVA New Media Research (Italy)
name: Avans University of Applied Sciences
Publisher: name: Zenodo
Year: 2024

description: Explore this case study collected by BioGov.net partners in Estonia! This valuable resource provides a quick and comprehensive understanding of the Bioeconomy, innovation and achieving climate neutrality in the rural economy case study.
Area Studies, Disziplinen und Regionen
Creators: name: Derichs, Claudia
Publisher: name: ASIEN: The German Journal on Contemporary Asia
Year: 2021

description: Turning 50 years of age allows for a retrospective look at the German Association for Asian Studies’ (DGA) trajectory over the last few decades. The article addresses the issue of Asia as the focal area for members of the DGA, the relationship between Area Studies and other (Social Science) disciplines, and the structural contexts to which both the DGA and its member community of scholars have adjusted their work — both willingly but also at times unwillingly too, because political conditions afforded a particular response. Through reflecting on Asia as an “entity” of scholarly endeavor, but also as a part of the globe having particular unique features and traits, the article discusses how Asian Area Studies have developed over time and to what extent the exercise of scholarly analysis has been shaped by changing paradigms such as the demand to “study with” people in Asia instead of performing the “study of” them. The DGA has been affected by such trends as well. On the whole, the assessment of the past five decades is a mixed and critical one, leading to the conclusion that the DGA can, in future, set the agenda for research on Asia that is both open to new perspectives and capable of integrating the ever more diverse community that its members make up.
description: ASIEN: The German Journal on Contemporary Asia, Nr. 144 (2017): ASIEN (Juli)
The physical activity habits and body image perceptions of students in a rural healthy Ontarian elementary school
Creators: name: Moore, Tracy
Publisher: name: Université d'Ottawa / University of Ottawa
Year: 2008
Subjects: subject: Education, Elementary.
subject: Health Sciences, Recreation.
subject: Biology, Physiology.

description: Since the Canadian educational reform in the 1990's, schools have included health education in their curriculum, and as all children under the age of 16 must attend school, on can ask "what better place to encourage health?" With this increased focus on health education, more schools are adopting a Comprehensive School Health (CSH) approach, yet as the CSH approach is not standardized in Canadian schools, school's choosing to adopt such principles must do so independently. In addition to independent adoption, school's who do chose to employ a CSH approach are under researched, resulting in little information on current CSH practices. This lack of research is prevalent in many countries, as researchers have acknowledged that the concept of the CSH approach is more advanced than its implementation (WHO, 1997). Therefore, by examining the physical activity habits and body image perceptions of rural students, this research sought to develop a better understating of a rural CSH approach. Results of this study demonstrated that this school's vice-principal and physical education teachers engaged in a series of health promoting initiatives. This school's joint development of their CSH approach was one of the factors that lead to their extensive application of the approach, as they benefited from the additional support of volunteers, government funding, pedagogical resources, and health professionals. With these unique opportunities, this school surpassed the level of CSH implementation that is presented in the current literature, by successfully implementing a Health Curriculum, a Healthy Environment, and providing an avenue for Health Services to begin. The students in this rural school demonstrated high levels of physical activity participation and body image satisfaction. Students credited their knowledge of health issues to their unique health education opportunities, parental and peer modeling, and their participation in regular physical activities.
La paz como objetivo de desarrollo territorial a través de la financiación de proyectos de inversión con recursos SGR PAZ de la subregión PDET Catatumbo, tras la firma del acuerdo final del conflicto en Colombia
Creators: name: Lis Campos, Carlos Francisco
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Cultura de paz - Aspectos sociales
subject: Desarrollo de la comunidad
subject: Comunidad - Aspectos socioeconómicos
subject: Implementación del acuerdo final de Paz
subject: Programas de desarrollo con enfoque territorial
subject: Desarrollo territorial
subject: Instrumentos de financiación
subject: Planeación territorial

description: ¿Como la financiación de proyectos de inversión con recursos SGR Paz inciden en el desarrollo territorial en la subregión PDET Catatumbo? Luego de una revisión de la literatura, este trabajo aborda un problema de investigación de política pública a partir de los instrumentos del acuerdo de Paz, en torno a la financiación y planeación en los territorios de las zonas PDET, específicamente la Subregión del Catatumbo y la forma de cómo promueven sus inversiones. Se analiza además, la forma en como los instrumentos de desarrollo territorial obtienen significado conforme los actores que intervienen y su incidencia en la construcción de paz, tomando como referente la caracterización de aprobación de los proyectos, partiendo de un enfoque metodológico de caso de estadística descriptiva y cualitativo sobre la base de priorización de las inversiones efectuadas con la implementación PDET; dando como resultado el desafío que tienen los territorios en especial Subregión del Catatumbo para financiar sus proyectos con recursos SGR Paz y la articulación de sus necesidades teniendo en cuenta la alta incidencia del conflicto y la baja capacidad institucional para promover proyectos de alto impacto, dando como resultado una baja participación de los recursos en esta subregión.
description: How does the financing of investment projects with SGR Paz resources affect territorial development in the PDET Catatumbo subregion? After a literature review, this paper addresses a public policy research problem based on the instruments of the Peace Agreement, regarding financing and planning in the territories of the PDET zones, specifically the Catatumbo Subregion and the way in which they promote their investments. It also analyzes the way in which the territorial development instruments obtain meaning according to the actors involved and their incidence in the construction of Peace, taking as a reference the characterization of approval of the projects, starting from a methodological approach of descriptive and qualitative statistics case on the basis of prioritization of the investments made with the PDET implementation; resulting in the challenge faced by the territories, especially the Catatumbo Subregion, to finance their projects with SGR Peace resources and the articulation of their needs taking into account the high incidence of conflict, the low institutional capacity to promote high impact projects, resulting in a statistically low participation of resources in this subregion.
title: Auditor‐provided non‐audit services and perceived audit quality: Evidence from the cost of equity and debt capital
Creators: name: Friedrich, Christian
name: Quick, Reiner
name: Schmidt, Florian
Publisher: name: Wiley-Blackwell
Year: 2024

description: There is an ongoing debate among regulators and researchers about concerns that the provision of non‐audit services (NAS) to audit clients may impair audit quality by reduced independence. In this context, there can be different perspectives on audit quality. Given recent regulatory changes in the European Union (EU) aimed to improve investor confidence in audited financial statements, it is critical to understand the association of NAS and audit quality perceptions by investors before and after the regulation. We investigate whether NAS affect shareholder and lender perceptions of audit quality, measured by the cost of debt and equity capital. For a sample of German firms, we find significant positive associations of NAS with both cost of debt and cost of equity. Other assurance and consultancy services drive this effect. We do not find this effect in the pre‐regulation period, but in the transition period when the regulation was passed but NAS restriction did not yet apply. In the post‐regulation period, it only persists for lenders. Thus, the EU regulation may have increased (or inadequately created) independence concerns for shareholders and lenders and curbed these concerns for shareholders only.
Victimizaciones contra la población LGBTI+ en el marco del conflicto armado interno colombiano : consecuencias del control social preestablecido y afectación del derecho a la reparación colectiva
Creators: name: Hernández Legarda, José Julián
Publisher: name: Universidad Externado de Colombia
Year: 2024
Subjects: subject: Conflicto armado - Aspectos sociales
subject: Población - Legislación
subject: Discriminación - Condiciones sociales
subject: LGBTI+
subject: Conflicto
subject: Víctimas
subject: Reparación
subject: Control
subject: OSIGEG

description: Ante el desconocimiento de las violencias ejercidas contra la población LGBTI+ en el conflicto armado interno colombiano, la falta de acceso a la justicia y la reparación de los derechos de esta población. Es necesario investigar porqué las personas LGBTI+, como colectivo sufrieron de hechos victimizantes y no han sido ampliamente reparadas en Colombia. De ahí que sea necesario indagar, qué paso antes de la ocurrencia de los hechos de violencia en el marco del conflicto armado interno, si existió o aún existe un control social preestablecido que permea las distintas esferas sociales, que incluye a los actores armados como sujetos de control territorial, a la sociedad colombiana y al Estado como sujetos necesarios para la reparación de las víctimas. Y de esta manera, conocer si el control social estructural acentúa e invisibiliza las violencias contra la población LGBTI+ en el conflicto armado interno y la garantía de su derecho a la reparación colectiva.
description: Given the lack of knowledge of the violence perpetrated against the LGBTI+ population in the Colombian internal armed conflict, the lack of access to justice and reparations for the rights of this population. It is necessary to investigate why LGBTI+ people, as a collective, suffered victimizing acts and have not been widely repaired in Colombia. Hence, it is necessary to investigate what happened before the occurrence of the acts of violence in the framework of the internal armed conflict, if there was or still is a pre-established social control that permeates the different social spheres, which includes the armed actors as subjects of territorial control, colombian society and the state as necessary subjects for the reparation of the victims. And in this way, to know if the structural social control accentuates and invisibilizes the violence against the LGBTI+ population in the internal armed conflict and the guarantee of their right to collective reparation.