cometadata/datacite-rtg-text-other-reclassification-records huggingface dataset:
Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort
Creators: name: Khandaker, Golam M.
name: Zuber, Verena
name: Rees, Jessica M. B.
name: Carvalho, Livia
name: Mason, Amy M.
name: Foley, Christopher N.
name: Gkatzionis, Apostolos
name: Jones, Peter B.
name: Burgess, Stephen
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/692/699/476/1414
/631/208
/631/154/53/2421
/692/53/2421
/38/43
article

description: Abstract: While comorbidity between coronary heart disease (CHD) and depression is evident, it is unclear whether the two diseases have shared underlying mechanisms. We performed a range of analyses in 367,703 unrelated middle-aged participants of European ancestry from UK Biobank, a population-based cohort study, to assess whether comorbidity is primarily due to genetic or environmental factors, and to test whether cardiovascular risk factors and CHD are likely to be causally related to depression using Mendelian randomization. We showed family history of heart disease was associated with a 20% increase in depression risk (95% confidence interval [CI] 16–24%, p < 0.0001), but a genetic risk score that is strongly associated with CHD risk was not associated with depression. An increase of 1 standard deviation in the CHD genetic risk score was associated with 71% higher CHD risk, but 1% higher depression risk (95% CI 0–3%; p = 0.11). Mendelian randomization analyses suggested that triglycerides, interleukin-6 (IL-6), and C-reactive protein (CRP) are likely causal risk factors for depression. The odds ratio for depression per standard deviation increase in genetically-predicted triglycerides was 1.18 (95% CI 1.09–1.27; p = 2 × 10−5); per unit increase in genetically-predicted log-transformed IL-6 was 1.35 (95% CI 1.12–1.62; p = 0.0012); and per unit increase in genetically-predicted log-transformed CRP was 1.18 (95% CI 1.07–1.29; p = 0.0009). Our analyses suggest that comorbidity between depression and CHD arises largely from shared environmental factors. IL-6, CRP and triglycerides are likely to be causally linked with depression, so could be targets for treatment and prevention of depression.
The functional identification of novel genes regulating telomere length in human cells
Creators: name: Gibson, Frederik
Publisher: name: University of Leicester
Year: 2022
Subjects: Uncategorized

description: Telomere length is a highly heritable trait associated with atherosclerotic cardiovascular disease and cancer, therefore identifying and understanding the mechanisms by which genes affect telomere length can have therapeutic benefits. A recent 1000 genomes-based imputation genome wide association study analysis of 46,898 European individuals across 22 cohorts identified genetic variants in 31 loci that associate with human leukocyte telomere length (LTL). Many contain genes known to regulate telomere length, e.g. components of the telomere capping shelterin complex or of the telomerase enzyme required for telomere length maintenance. However, 13 loci cannot be linked to any known telomere regulator, suggesting they may contain genes with previously unidentified roles in telomere biology. The aim of this thesis was to identify these novel genes, investigate how they may regulate telomere biology and uncover the precise pathway through which this is achieved.Bioinformatics analyses investigated the effects of LTL associated SNPs on gene expression and the amino acid sequence, linking 7 loci with potential candidate genes. A screen was developed which enabled the regulation of telomere maintenance or telomere protection by candidates to be detected. This was achieved through the utilisation of siRNA-induced gene knockdowns and measurement of acute effects on telomerase activity and activation of the DNA damage response, indicative of telomere deprotection. The genes with the strongest evidence linking them to telomere biology – MPHOSPH6, PAPD4, SENP7 and DCAF4 – were selected for screening.MPHOSPH6 was identified as a promoter of telomerase activity through its involvement in the complex maturation of TERC, the RNA component of telomerase, however the precise mechanism is still to be fully elucidated. Preliminary evidence indicative of the regulation of DNA repair and telomere protection by DCAF4 was also produced, however evidence supporting a link between telomere biology and the activity of PAPD4 and SENP7 was not generated.
Entomobrya bioblitzi Jordana & Greenslade 2020, sp. nov.
Creators: name: Jordana, Rafael
name: Greenslade, Penelope
Publisher: name: Zenodo
Year: 2020
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Entognatha
Collembola
Entomobryidae
Entomobrya
Entomobrya bioblitzi

description: Entomobrya bioblitzi sp. nov.
(Figs 1D, 9 A–E)
Holotype. Male, NSW, Thredbo NP, alpine meadow, - 36.504722°S, 148.305556°E, 2037m asl, pitfall, January 2012, PG leg., [SAMA 22640].
Description. Size. Length 1.512 mm.
Colour. As indicated on label in having an orange head, as well as Abd V, VI (Fig. 1D).
Head. Eight eyes, G and H smaller than E–F. Antennae unknown. Labral papillae spinulate with three spines on each papilla (Fig. 9A). Labral chaetae with 4 prelabral and 5,5,4 chaetae, all smooth. Labial chaetae with MREL 1 L 2 ciliated, R smaller than M. External process of papilla E not reaching the papilla tip.
Thorax and abdomen. Length ratio of Abd IV/III=5.5. Tibiotarsus without differentiated chaetae, with exception of the presence of the smooth terminal chaetae on legs 3, characteristic for the genus. Trochanteral organ with 16-20 chaetae. Unguis with 4 teeth: paired at 50% of the basis, first unpaired at 75 % from the basis, dorsal and lateral teeth a little below the internal paired. Unguiculus acuminated, narrow, external lamella of leg 3 serrate. Tenent hair clavate, longer than unguis. Manubrial plate with 4 chaetae and 2 pseudopores. Mucro bidentate both teeth of similar size with mucronal basal spine. Mucro 15 micrometers and distal smooth portion of dens 2.5 times the mucro length.
Macrochaetotaxy. Simplified Mc formula: 4,1,0,1(2),1a/2,3/0,2/0,0,1/0,2,2,0,2. Head chaetotaxy (Fig. 9B) An 2, An 3a2, An 3a1, An 3 and A 5. M 2 and M 4 present as Mc. In sutural row present S 0, S 2, S 3, S 4i (present or absent), S 5i, S 5 and Ps 5 present. Thorax chaetotaxy: Th II chaetotaxy (Fig. 9C) T1 area with Mac m 1 and m 2, T2 area with Mc a 5, m 4, m 4i. Abdominal chaetotaxy (Fig. 9D): Abd II with m 3ep and m 3e, on Abd III m 3 Mc present; Abd IV (Fig. 9E) with Mc A 2, A 4, A 6, B 4, B 6, and E 1. Sensillary formula usual of Entomobrya. The bothriotricha on Abd IV in position T 2 and T 4 (0110).
Remarks. One specimen only was available. The colour of the fresh specimen was described on the slide. Taking into account only the chaetotaxy of the abdominal segments II and III 0,2 / 0,0,1, the only species with the same chaetotaxy of world Entomobrya are: E. assuta, E. boreensis sp. nov., E. clarki, E durrasensis sp. nov. and E. stirlingensis sp. nov. In the attached Table 4, the characters listed for E. bioblitzi easily separate it from the five species above. Table 4
Etymology. The species is named after the Bioblitz field expedition organised by NSW National Parks Officer, Ken Green in 2012.
description: Published as part of Jordana, Rafael & Greenslade, Penelope, 2020, Biogeographical and ecological insights from Australasian faunas: the megadiverse collembolan genus, Entomobrya (Entomobryidae), pp. 1-104 in Zootaxa 4770 (1) on pages 22-24, DOI: 10.11646/zootaxa.4770.1.1, http://zenodo.org/record/3797958
A Framework for Estimating the Linked Economic Contribution of Cotton Production, Ginning, Oilseed Milling, and Warehousing
Creators: name: Dudensing, Rebekka M.
name: Park, John
name: Robinson, John
name: Hanselka, Dan
name: Martinez, Charles C.
name: Dudensing, Rebekka M.
name: Park, John
name: Robinson, John
name: Hanselka, Dan
name: Martinez, Charles C.
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Community/Rural/Urban Development
subject: Crop Production/Industries
subject: Production Economics
subject: Research Methods/ Statistical Methods
subject: Teaching/Communication/Extension/Profession
subject: Cotton
subject: Economic impact
subject: Economic contribution
subject: Forward-linked impact

description: This poster presents a framework and templates for estimating the economic contribution of the cotton industry, including production, ginning, oilseed milling, and warehousing. The IMPLAN default cotton sector is modified to represent regional production functions using Extension crop budgets. Ginning, cottonseed milling, and warehousing include backward linkages to cotton production that can result in double-counting expenditures. Furthermore, they are sub-industries within broader IMPLAN sectors that contain other important components of the Texas and agricultural economies, so they should not be exclusively modified to fit specific cotton tasks. We survey gins, cottonseed mills, and warehouses in two Texas regions to modify those IMPLAN expenditure patterns. Because ginning is actually a backward link in IMPLAN, a portion of IMPLAN sector 19 expenditures are subtracted. Then analysis-by-parts is used to estimate the ginning, cottonseed milling, and warehousing contributions under both cooperative and corporate ownership. Economists can easily use the developed templates (1) to modify production functions to represent their region and (2) to estimate the economic contributions of the linked industry and its individual components without double-counting inputs and distorting other aspects of the ag support services, oilseed milling, and warehousing sectors.
Associations of Physical Activity and Sedentary Behaviour with Vision-Threatening Diabetic Retinopathy in Indonesian Population with Type 2 Diabetes Mellitus: Jogjakarta Eye Diabetic Study in the Community (JOGED.COM)
Creators: name: Universitas Gadjah Mada
Publisher: name: figshare
Year: 2019
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: A community-based cross-sectional study of adults with type 2 diabetes. DR was assessed from disc- and macula-centred fundus photograph, and categorised into mild, moderate non-proliferative DR (NPDR), and Vision-Threatening DR (VTDR). Worse eye was used to determine the person’s DR severity. PA was assessed using WHO Global Physical Activity Questionnaire (GPAQ). All of the PA components, including daily sitting time, walking distance, sleeping duration, and exercise were converted based on the physical activity ratio and then calculated tomobtain the mean physical activity level (PAL). The mean PAL was then classified into sedentary, moderate, and vigorous lifestyle. There were 1116 participants, 43.1% with any DR and 26.3% VTDR. The prevalence of DR/VTDR in sedentary, moderate, and vigorous physical activity group was 41.9%/22.7%, 39.2%/23.9%, and 32.7%/20.4% respectively. A longer duration of daily sedentary lifestyle (>3 hours) was significantly associated with presence of DR (OR 1.66; 95% CI 1.17–2.35; p < 0.01) and VTDR (OR 1.74; 1.16–2.62; p < 0.01). These associations remained significant after adjusting for age, gender, duration of diabetes, systolic blood pressure and physical activity. There was no significant association between sleeping duration, walking distance, and vigorous activity and DR. In this study, prolonged daily sedentary activity was strongly associated with VTDR. This finding suggests that public health campaign for reducing daily sedentary activities in individuals with type 2 diabetes may offer benefit to reduce the burden of DR and VTDR.
Energy Independent Solution to the Solar Neutrino Anomaly including the SNO data
Creators: name: Choubey, Sandhya
name: Goswami, Srubabati
name: Roy, D. P.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: The global data on solar neutrino rates and spectrum, including the SNO charged current rate, can be explained by LMA, LOW or the energy independent solution -- corresponding to near-maximal mixing. All the three favour a mild upward renormalisation of the Cl rate. A mild downward shift of the $B$ neutrino flux is favoured by the energy independent and to a lesser extent the LOW solution, but not by LMA. Comparison with the ratio of SK elastic and SNO charged current scattering rates favours the LMA over the other two solutions, but by no more than $1.5σ$.
description: 18 pages, latex, 3 figures
Similarities and Differences of Animal Welfare Perceptions between U.S. Cow-Calf Producers and the Public
Creators: name: McKendree, Melissa G.S.
name: Tonsor, Glynn T.
name: Wolf, Christopher A.
name: McKendree, Melissa G.S.
name: Tonsor, Glynn T.
name: Wolf, Christopher A.
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Agricultural and Food Policy
subject: Consumer/Household Economics
subject: Demand and Price Analysis
subject: Livestock Production/Industries
subject: Marketing
subject: FOS: Economics and business
subject: Production Economics
subject: animal welfare
subject: beef
subject: best-worst scaling
subject: cattle
subject: demand
subject: economics
subject: supply

description: The U.S. livestock industry is increasingly faced with pressure to adjust practices in response to societal concerns. A specific area of growing concern surrounds how production practices impact the welfare of farm animals. The objective of this analysis is to use best-worst scaling (maximum difference) to determine which practices the U.S. public and cow-calf producers view as the most effective and most practical practices to improve the welfare of beef cattle in the U.S. In meeting this objective, we determine similarities and differences in the public and producer views. Random parameters logit and latent class models are used to better understand heterogeneity within and across both the public and producers. Results indicate that both the U.S. public and cow-calf producers viewed providing access to fresh, clean feed and water appropriate for the animal’s physiological state, and providing adequate comfort through the use of shade, windbreaks, and ventilation assuring clean, dry, sanitary environmental conditions for cattle as both the most effective and most practical practices to improve the welfare of beef cattle. The practices which were viewed as the least effective and least practical were to castrate male calves either within the first three months of age or with pain control, and dehorn/disbud calves either before horn tissue adheres to the skull or with pain control. Implications for future research, possible verification programs, and related debates regarding beef cattle welfare are provided.
Agricultural Productivity and Climate Change in the Greater Middle East
Creators: name: Tayebi, Zahra
name: Fulginiti, Lilyan E.
name: Tayebi, Zahra
name: Fulginiti, Lilyan E.
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agricultural and Food Policy
subject: International Development
subject: Production Economics
subject: Productivity Analysis
subject: Agricultural productivity
subject: Climate change
subject: Greater Middle East
subject: Stochastic frontier

description: The main purpose of this research is to determine the potential impact of weather variables on agricultural productivity for Afghanistan, Iran, Pakistan, Turkey and Syria. A translog production function was used in estimating TFP growth in agriculture over the period 1980-2010. Precipitation, temperature, drought and irrigation were included in the analysis. The results indicate increasing agricultural productivity during the period with innovations contributing approximately 30% to agricultural output growth. Temperature and precipitation play a significant role in agricultural production and most frequent extreme drought episodes and irrigation affect, substantially, agricultural productivity growth in the region.
Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians
Creators: name: Luo, Yang
name: Suliman, Sara
name: Asgari, Samira
name: Amariuta, Tiffany
name: Baglaenko, Yuriy
name: Martínez-Bonet, Marta
name: Ishigaki, Kazuyoshi
name: Gutierrez-Arcelus, Maria
name: Calderon, Roger
name: Lecca, Leonid
name: León, Segundo R.
name: Jimenez, Judith
name: Yataco, Rosa
name: Contreras, Carmen
name: Galea, Jerome T.
name: Becerra, Mercedes
name: Nejentsev, Sergey
name: Nigrovic, Peter A.
name: Moody, D. Branch
name: Murray, Megan B.
name: Raychaudhuri, Soumya
Publisher: name: Apollo - University of Cambridge Repository
Year: 2019
Subjects: Article
/631/250/248
/631/250/255/1318
/631/208/205/2138
/692/699/255/1856
/45
/45/43
/38/91
/49/91
/49/23
article

description: Abstract: Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5–15% will develop active tuberculosis (TB). Approximately half will progress to active TB within the first 18 months after infection, presumably because they fail to mount an effective initial immune response. Here, in a genome-wide genetic study of early TB progression, we genotype 4002 active TB cases and their household contacts in Peru. We quantify genetic heritability (hg2) of early TB progression to be 21.2% (standard error 0.08). This suggests TB progression has a strong genetic basis, and is comparable to traits with well-established genetic bases. We identify a novel association between early TB progression and variants located in a putative enhancer region on chromosome 3q23 (rs73226617, OR = 1.18; P = 3.93 × 10−8). With in silico and in vitro analyses we identify rs73226617 or rs148722713 as the likely functional variant and ATP1B3 as a potential causal target gene with monocyte specific function.
Additional file 1 of Is there a role for cementless primary stem in hip arthroplasty for early or late fixation failures of intertrochanteric fractures?
Creators: name: Ma, Hsuan-Hsiao
name: Chou, Te-Feng Arthur
name: Tsai, Shang-Wen
name: Chen, Cheng-Fong
name: Wu, Po-Kuei
name: Chen, Wei-Ming
Publisher: name: figshare
Year: 2022
Subjects: subject: Medicine
subject: Cell Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Developmental Biology
subject: Science Policy
subject: 110309 Infectious Diseases
subject: FOS: Health sciences

description: Additional file 1: Table S1. Surgical complications (comparing initial plate fixation and nail fixation).
Mathematical Modelling of Translation and Rotation Movement in Quad Tiltrotor
Creators: name: Universitas Gadjah Mada
Publisher: name: figshare
Year: 2019
Subjects: subject: 10399 Numerical and Computational Mathematics not elsewhere classified
subject: FOS: Mathematics

description: Quadrotor as one type of UAV (Unmanned Aerial Vehicle) is an underactuated mechanical system. It means that the system has some control inputs is lower than its DOF (Degrees of Freedom). This condition causes quadrotor to have limited mobility because of its inherent under actuation, namely, the availability of four independent control signals (four-speed rotating propellers) versus 6 degrees of freedom parameterizing quadrotor position or orientation in space. If a quadrotor is made to have 6 DOF, a full motion control system to optimize the flight will be different from before. So it becomes necessary to develop over actuated quad tiltrotor. Quad tiltrotor has control signals more than its DOF. Therefore, we can refer it to the overactuated system. We need a good control system to fly the quad tiltrotor. Good control systems can be designed using the model of the quad tiltrotor system. We can create quad tiltrotor model using its dynamics based on Newton-Euler approach. After we have a set of model, we can simulate the control system using some control method. There are several control methods that we can use in the quad tiltrotor flight system. However, we can improve the control by implementing a modern control system that uses the concept of state space. The simulations show that the quad tiltrotor has done successful translational motion without significant interference. Also, undesirable rotation movement in the quad tiltrotor flight when performing the translational motions resulting from the transition process associated with the tilt rotor change was successfully reduced below 1 degree.
Gravitational Wave Anisotropies from Primordial Black Holes
Creators: name: Bartolo, N.
name: Bertacca, D.
name: De Luca, V.
name: Franciolini, G.
name: Matarrese, S.
name: Peloso, M.
name: Ricciardone, A.
name: Riotto, A.
name: Tasinato, G.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Cosmology and Nongalactic Astrophysics (astro-ph.CO)
subject: General Relativity and Quantum Cosmology (gr-qc)
subject: High Energy Physics - Phenomenology (hep-ph)
subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: An observable stochastic background of gravitational waves is generated whenever primordial black holes are created in the early universe thanks to a small-scale enhancement of the curvature perturbation. We calculate the anisotropies and non-Gaussianity of such stochastic gravitational waves background which receive two contributions, the first at formation time and the second due to propagation effects. The former contribution can be generated if the distribution of the curvature perturbation is characterized by a local and scale-invariant shape of non-Gaussianity. Under such an assumption, we conclude that a sizeable magnitude of anisotropy and non-Gaussianity in the gravitational waves would suggest that primordial black holes may not comply the totality of the dark matter.
description: 20 pages, 5 figures, version accepted by JCAP
White-tailed Deer Semen Auction Data: A Hedonic Analysis
Creators: name: Barnes, Kenneth R.
name: Franken, Jason R.
name: Wolfskill, L.A.
name: Nair, Shyam S.
name: Mills, Foy D.
name: Ullrich, Doug R.
name: Barnes, Kenneth R.
name: Franken, Jason R.
name: Wolfskill, L.A.
name: Nair, Shyam S.
name: Mills, Foy D.
name: Ullrich, Doug R.
Publisher: name: Unknown
Year: 2016
Subjects: subject: Agribusiness
subject: Demand and Price Analysis
subject: hedonic price analysis
subject: white-tailed deer
subject: semen prices
subject: cervid

description: In 2008, the cervid (i.e., deer) production and hunting industry had an economic impact of $318.4 million in Texas and $3 billion in the US. Antlers of white-tailed bucks are prized trophies for hunters, and hence, breeders make great investments to manage genetic potential for antler growth in their herds. This study identified the factors that influenced white-tailed deer semen prices using hedonic analysis of publicly available auction data from the Texas Deer Association. Results indicated that higher antler scores (p<0.0001), Texas genetics (p<0.0001), and deceased bucks (p<0.0432) significantly and positively influenced price per straw of semen.
title: 02_1075
Creators: name: Wesley Baldwin, John
name: Baldwin, John W.
Publisher: name: NAKALA - https://nakala.fr (Huma-Num - CNRS)
publisherIdentifier: https://ror.org/04ces3204
publisherIdentifierScheme: ROR
Year: 2018
Subjects: subject: LaMOP
subject: Laboratoire de Médiévistique Occidentale de Paris

description: L'ensemble de ces notes ont été crée par John Baldwin lors d'une de ses premières périodes de résidence à Paris. Ces documents comprennent tous les magistri qu’il avait pu rencontrer dans ses sources. Aux XIIème et XIIIème siècles, les universités n'existant pas encore, le titre de magister s'il évoque certainement une compétence n'est pas rattaché de façon systématique au passage par les écoles. De surcroît, les magistris sont le plus souvent désignés par leur seul prénom. La lecture de ces données est donc difficile et suppose un long travail pour tenter d'identifier un individu auquel on pourrait rattacher plusieurs mentions. John Baldwin avait donc renoncé à utiliser ces données pour donner un prolongement à sa magnifique étude sur les gradués d'université et leur emploi par les Capétiens et les Plantagenêts. Néanmoins, il a conservé ces données et elles sont potentiellement très utile dans le cadre de Studium, comme le sont toutes les mentions dans les volumes des Fasti Ecclesiae Gallicanae de chanoines portant ce titre de magister sans autres précisions. L'ampleur des dépouillements rend ces données très utiles et nous devons une grande reconnaissance à John Baldwin pour avoir pris la peine de faire photocopier ses fiches et de nous les avoir transmises amicalement.
Les données ainsi que les images des fiches sont accessibles sur le site Internet à l'adresse suivante : http://studium-baldwin.lamop.fr/.
Les transcriptions des fiches ont été effectuées par des étudiants de Paris 1 Panthéon - Sorbonne mais elles n'ont pas été corrigées par la suite.
description: Relation: https://lamop.hypotheses.org/
The Absence of C-5 DNA Methylation in Leishmania donovani Allows DNA Enrichment from Complex Samples
Creators: name: Cuypers, Bart
name: Dumetz, Franck
name: Meysman, Pieter
name: Laukens, Kris
name: De Muylder, Géraldine
name: Dujardin, Jean-Claude
name: Domagalska, Malgorzata Anna
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Leishmania
trypanosomatids
DNA-methylation
epigenomics
whole-genome bisulfite sequencing
DNA-enrichment

description: Cytosine C5 methylation is an important epigenetic control mechanism in a wide array of eukaryotic organisms and generally carried out by proteins of the C-5 DNA methyltransferase family (DNMTs). In several protozoans, the status of this mechanism remains elusive, such as in Leishmania, the causative agent of the disease leishmaniasis in humans and a wide array of vertebrate animals. In this work, we showed that the Leishmania donovani genome contains a C-5 DNA methyltransferase (DNMT) from the DNMT6 subfamily, whose function is still unclear, and verified its expression at the RNA level. We created viable overexpressor and knock-out lines of this enzyme and characterized their genome-wide methylation patterns using whole-genome bisulfite sequencing, together with promastigote and amastigote control lines. Interestingly, despite the DNMT6 presence, we found that methylation levels were equal to or lower than 0.0003% at CpG sites, 0.0005% at CHG sites, and 0.0126% at CHH sites at the genomic scale. As none of the methylated sites were retained after manual verification, we conclude that there is no evidence for DNA methylation in this species. We demonstrated that this difference in DNA methylation between the parasite (no detectable DNA methylation) and the vertebrate host (DNA methylation) allowed enrichment of parasite vs. host DNA using methyl-CpG-binding domain columns, readily available in commercial kits. As such, we depleted methylated DNA from mixes of Leishmania promastigote and amastigote DNA with human DNA, resulting in average Leishmania:human enrichments from 62× up to 263×. These results open a promising avenue for unmethylated DNA enrichment as a pre-enrichment step before sequencing Leishmania clinical samples.
Chemische Untersuchung der Teinacher Mineralquellen
Creators: name: Fehling, Hermann Christian von
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1859

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 15-16, 1859-1860
Poincare Invariant Algebra From Instant to Light-Front Quantization
Creators: name: Ji, Chueng-Ryong
name: Mitchell, Chad
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We present the Poincare algebra interpolating between instant and light-front time quantizations. The angular momentum operators satisfying SU(2) algebra are constructed in an arbitrary interpolation angle and shown to be identical to the ordinary angular momentum and Leutwyler-Stern angular momentum in the instant and light-front quantization limits, respectively. The exchange of the dynamical role between the transverse angular mometum and the boost operators is manifest in our newly constructed algebra.
description: 21 pages, 3 figures, 1 table
Ueber das Os interparietale und das Vorkommen von abortiven Schneidezähnen im Oberkiefer bei mehreren Arten der Gattung Hyrax
Creators: name: Jäger, Georg Friedrich von
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1859

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 15-16, 1859-1860
Accelerometer-Based Recorder of Fingers Dynamic Movements for Post-Stroke Rehabilitation
Creators: name: Universitas Gadjah Mada
Publisher: name: figshare
Year: 2019
Subjects: subject: 90399 Biomedical Engineering not elsewhere classified
subject: FOS: Medical engineering

description: Stroke is a disease that currently attracts more attention in Indonesia according to the statistics provided by the Ministry of Health of the Republic of Indonesia. This research was motivated by the shortage of physiotherapists which can not catch the increasing number of stroke patients. The therapy becomes less effective and less efficient since each therapist must handle too many patients during his/her work hours. This research has developed a device prototype that can help the therapy to measure and monitor patient exercise, especially at the final stage of rehabilitation when the patient gets therapy to move actively. The angle of the moving body parts that can represent the ability of patient motion was measured using accelerometers. The developed prototype was in the form of a glove, equipped with an Arduino Nano and two accelerometer modules, that measures the motion of the thumb and index finger. The device was calibrated and tested to determine the characteristics of the sensors. This test showed that the gloves prototype had an accuracy of 95,8% and precision of 99,6%. The application of the prototype was carried out on four types of finger movements, namely thumb abduction-adduction, thumb flexion-extension, finger flexion-hyperextension, and finger abduction adduction. The prototype was also tested for its ability to work in variations of direction and position of the hand.
The Indonesian general practitioners’ perspectives on formal postgraduate training in primary care
Creators: name: Universitas Gadjah Mada
Publisher: name: figshare
Year: 2019
Subjects: subject: 111799 Public Health and Health Services not elsewhere classified
subject: FOS: Health sciences

description: This study aims to explore the general practitioner (GP)'s views and perspectives related to the formal postgraduate training in primary care that may influence their enrolment in PCP program. We conducted semi-structured interviews with a topic guide. The study took place in Yogyakarta from January to December 2016. The participants were GPs practicing in Yogyakarta primary care clinics who were recruited using purposive-maximum variation sample design. The interviews were audio-recorded and transcribed. The data were analysed using interpretative phenomenological analysis approach. Nineteen GPs participants were involved in this study. Three major themes were identified, namely unfamiliarity, resistance, and positivism. Almost all the GP participants were unfamiliar with the primary care training program. They were also pessimistic if the training could change the health service in the country while it lacked resources and infrastructures. However, exposure to the training brought positive insights that it could improve the doctors’ knowledge and skills in primary care practice. The government intention to establish PCP training is currently on the right tract. However, information dissemination and more supports in primary care are also essential.
E_6 Unification with Bi-Large Neutrino Mixing
Creators: name: Bando, Masako
name: Maekawa, Nobuhiro
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: A scenario of SO(10) grand unified theory (GUT) proposed by one of the authors is extended to E_6 unification. This gives realistic quark and lepton mass matrices. In neutrino sector, the model reproduces large mixing angle (LMA) MSW solution as well as large mixing angle for atmospheric neutrino anomaly. In this model, right-handed down quark and left-handed lepton of the first and second generation belong to a single multiplet 27. This causes natural suppression of flavor changing neutral current(FCNC).
description: 23 pages, V2:published version
How are emergent constraints quantifying uncertainty and what do they leave behind?
Creators: name: Williamson, Daniel B.
name: Sansom, Philip G.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Applications (stat.AP)
subject: FOS: Computer and information sciences

description: The use of emergent constraints to quantify uncertainty for key policy relevant quantities such as Equilibrium Climate Sensitivity (ECS) has become increasingly widespread in recent years. Many researchers, however, claim that emergent constraints are inappropriate or even under-report uncertainty. In this paper we contribute to this discussion by examining the emergent constraints methodology in terms of its underpinning statistical assumptions. We argue that the existing frameworks are based on indefensible assumptions, then show how weakening them leads to a more transparent Bayesian framework wherein hitherto ignored sources of uncertainty, such as how reality might differ from models, can be quantified. We present a guided framework for the quantification of additional uncertainties that is linked to the confidence we can have in the underpinning physical arguments for using linear constraints. We provide a software tool for implementing our general framework for emergent constraints and use it to illustrate the framework on a number of recent emergent constraints for ECS. We find that the robustness of any constraint to additional uncertainties depends strongly on the confidence we can have in the underpinning physics, allowing a future framing of the debate over the validity of a particular constraint around the underlying physical arguments, rather than statistical assumptions.
Quantisation of θ-expanded non-commutative QED
Creators: name: Grimstrup, Jesper M.
name: Wulkenhaar, Raimar
Publisher: name: arXiv
Year: 2002
Subjects: subject: High Energy Physics - Theory (hep-th)
subject: FOS: Physical sciences

description: We analyse two new versions of θ-expanded non-commutative quantum electrodynamics up to first order in θand first loop order. In the first version we expand the bosonic sector using the Seiberg-Witten map, leaving the fermions unexpanded. In the second version we leave both bosons and fermions unexpanded. The analysis shows that the Seiberg-Witten map is a field redefinition at first order in θ. However, at higher order in θthe Seiberg-Witten map cannot be regarded as a field redefinition. We find that the initial action of any θ-expanded massless non-commutative QED must include one extra term proportional to θwhich we identify by loop calculations.
description: 24 pages, LaTeX, uses the feynmf package
Die classischen Conchylien-Namen
Creators: name: Martens, Eduard von
Publisher: name: - NO PUBLISHER DEFINED -
Year: 1859

description: Jahreshefte des Vereins für Vaterländische Naturkunde in Württemberg : zugl. Jahrbuch d. Staatlichen Museums für Naturkunde in Stuttgart
description: Bd. 15-16, 1859-1860
Malaysia as an “Other” in Indonesian popular discourse
Creators: name: Universitas Gadjah Mada
Publisher: name: figshare
Year: 2019
Subjects: subject: 200202 Asian Cultural Studies
subject: FOS: Other humanities

description: This article reads contemporary popular publications in Indonesia on the topic of Indonesian–Malaysian relations. It looks at how Indonesia perceives Malaysia and the function of that perception in relation to Indonesian national identity. The article also looks at how Indonesian perceptions of Malaysia were discussed during the revolutionary period by reading the speeches held at the constitutional meeting (BPUPKI) and the Konfrontasi period, reading the speeches written by Sukarno and the letter of Pan-Malay leader exiled in Indonesia, Ibrahim Yaacob. The article then compares the ideas espoused by Sukarno, Yaacob and others in the past and the arguments presented in the present day concerning Malaysia. A preliminary conclusion is reached that geopolitical anxiety and not kinship is a more important factor in how contemporary Indonesia sees Malaysia.
Superior strength–ductility combination in Al alloys via dislocation gradient structure
Creators: name: Wang, Feng
name: Li, Yue
name: Chen, Xinren
name: Zhao, Huan
name: Yaqoob, Khurram
name: Du, Yong
name: Wang, Zhangwei
name: Song, Min
Publisher: name: Taylor & Francis
Year: 2022
Subjects: subject: Biophysics
subject: Space Science
subject: Physical Sciences not elsewhere classified
subject: Medicine
subject: Cell Biology
subject: Molecular Biology
subject: Evolutionary Biology
subject: FOS: Biological sciences
subject: Biological Sciences not elsewhere classified
subject: Developmental Biology

description: The precipitation hardening is widely applied to strengthen Al alloys. Here, we report an alternative way to achieve high-strength Al alloys via forming the dislocation gradient through pre-torsion. Remarkably, the gradient Al alloys exhibit a sharp increase in ultimate tensile strength up to 605 MPa yet nearly without reducing the uniform elongation, thereby outperforming their counterparts. The superior strength–ductility combination is ascribed to the excellent strengthening and strain hardening effects stemming from the substantial hetero-deformation-induced hardening in the coarse-grained gradient Al alloys. Our study thus paves a new way to improve the mechanical properties of Al alloys. The gradient distribution of dislocations significantly increases the strength of the Al alloy with the neglectable reduction in uniform elongation, which enables exceptional mechanical properties that outperform the peak-aged counterpart.
New ways to explore factorization in b decays
Creators: name: Diehl, M.
name: Hiller, G.
Publisher: name: arXiv
Year: 2001
Subjects: subject: High Energy Physics - Phenomenology (hep-ph)
subject: FOS: Physical sciences

description: We propose to study factorization breaking effects in exclusive b decays where they are strongly enhanced over the factorizing contributions. This can be done by selecting final-state mesons with a small decay constant or with spin greater than one. We find a variety of decay modes which could help understand the dynamical origin of factorization and the mechanisms responsible for its breaking.
description: 30 pages, 5 figures, references added, signs corrected in eqs. 10-13,19,20
Evaluating Benefits and Costs of Cover Crops in Cotton Production System in Northwest Louisiana
Creators: name: Adusumilli, Naveen
name: Fromme, Daniel
name: Adusumilli, Naveen
name: Fromme, Daniel
Publisher: name: Unknown
Year: 2016
Subjects: subject: Production Economics
subject: Resource /Energy Economics and Policy
subject: Cover crops
subject: incentives
subject: conservation
subject: capital budgeting

description: Cover crop adoption by producers as part of a production cycle depends on their objectives regrading time management, cost vs benefits, and environmental obligations. A myriad of studies that examined the economics of cover crops found them to be often idiosyncratic, i.e., results depend on the region, weather patterns, soil type, and management practices. The studies determined that lack of long-term economic outlook for the incorporation of cover crops as one of the factors for their minimal adoption in many parts of the country. Thus, we aim to assess the economic impact of long-term adoption of cover crops as part of a production cycle. Partial budgeting tool, CoverCropEconomics, is used to generate the overall costs and benefits. The data on agronomic variables, i.e., yield, organic matter, applied nitrogen, soil microbial counts, and among others are obtained from a 30-year cover crop research conducted in Northwest Louisiana. The research reported a significant increase in yield for crops planted following cover crops. Additionally, research shows improvements in soil nitrogen and soil organic matter suggesting added profits to the farmer. Accounting for those economic and agronomic variables, overall long term net benefits of incorporating cover crops amount to 1,354 per acre, with majority of the benefits contribution through yield increase of cash crop. The results can be useful for conservation agencies to evaluate their current incentive payments toward cover crop adoption.
Relativistic approach to the kinematics of large-scale peculiar motions
Creators: name: Tsaprazi, Eleni
name: Tsagas, Christos G.
Publisher: name: Apollo - University of Cambridge Repository
Year: 2020
Subjects: Regular Article - Theoretical Physics

description: Abstract: We consider the linear kinematics of large-scale peculiar motions in a perturbed Friedmann universe. In so doing, we take the viewpoint of the “real” observers that move along with the peculiar flow, relative to the smooth Hubble expansion. Using relativistic cosmological perturbation theory, we study the linear evolution of the peculiar velocity field, as well as the expansion/contraction, the shear and the rotation of the bulk motion. Our solutions show growth rates considerably stronger than those of the earlier treatments, which were mostly Newtonian. On scales near and beyond the Hubble radius, namely at the long-wavelength limit, peculiar velocities are found to grow as a2, in terms of the scale factor, instead of the Newtonian a1/2-law. We attribute this to the fact that, in general relativity, the energy flux, triggered here by the peculiar motion of the matter, also contributes to the local gravitational field. In a sense, the bulk flow gravitates, an effect that has been bypassed in related relativistic studies. These stronger growth-rates imply faster peculiar velocities at horizon crossing and higher residual values for the peculiar-velocity field. Alternatively, one could say that our study favours bulk peculiar flows larger and faster than anticipated.
Quantum Data-Syndrome Codes
Creators: name: Ashikhmin, Alexei
name: Lai, Ching-Yi
name: Brun, Todd A.
Publisher: name: arXiv
Year: 2019
Subjects: subject: Quantum Physics (quant-ph)
subject: Information Theory (cs.IT)
subject: FOS: Physical sciences
subject: FOS: Computer and information sciences

description: Performing active quantum error correction to protect fragile quantum states highly depends on the correctness of error information--error syndromes. To obtain reliable error syndromes using imperfect physical circuits, we propose the idea of quantum data-syndrome (DS) codes that are capable of correcting both data qubits and syndrome bits errors. We study fundamental properties of quantum DS codes, including split weight enumerators, generalized MacWilliams identities, and linear programming bounds. In particular, we derive Singleton and Hamming-type upper bounds on degenerate quantum DS codes. Then we study random DS codes and show that random DS codes with a relatively small additional syndrome measurements achieve the Gilbert-Varshamov bound of stabilizer codes. Constructions of quantum DS codes are also discussed. A family of quantum DS codes is based on classical linear block codes, called syndrome measurement codes, so that syndrome bits are encoded in additional redundant stabilizer measurements. Another family of quantum DS codes is CSS-type quantum DS codes based on classical cyclic codes, and this includes the Steane code and the quantum Golay code.
description: 18 pages, 4 figures. This version comprehensively extends our previous paper (arXiv:1602.01545)
Additional file 11: of Mapping and identification of CsUp, a gene encoding an Auxilin-like protein, as a putative candidate gene for the upward-pedicel mutation (up) in cucumber
Creators: name: Sun, Jingxian
name: Xiao, Tingting
name: Nie, Jingtao
name: Chen, Yue
name: Lv, Duo
name: Pan, Ming
name: Gao, Qifan
name: Guo, Chunli
name: Zhang, Leyu
name: He, Huan-Le
name: Lian, Hongli
name: Pan, Junsong
name: Cai, Run
name: Wang, Gang
Publisher: name: figshare
Year: 2019
Subjects: subject: Biochemistry
subject: Microbiology
subject: FOS: Biological sciences
subject: Genetics
subject: Molecular Biology
subject: Evolutionary Biology
subject: Information Systems not elsewhere classified
subject: Developmental Biology
subject: Infectious Diseases
subject: FOS: Health sciences
subject: Plant Biology
subject: Virology

description: Figure S10. Alignment of promoter sequence of CsUP from WT and up. (PDF 108 kb)
Meteorus cis
Creators: name: Stigenberg, Julia
name: Ronquist, Fredrik
Publisher: name: Zenodo
Year: 2011
Subjects: Biodiversity
Taxonomy
Animalia
Arthropoda
Insecta
Hymenoptera
Braconidae
Meteorus
Meteorus cis

description: Meteorus cis (Bouché)
Fig. 91
 Bracon cis Bouché, 1834:149. Type material unknown.
 Perilitus profligator Haliday, 1835:33. Syntypes ♀ Ireland (lost). Synonymized by Fahringer 1928:505.
 Diagnosis: Meteorus cis is similar to M. breviantennatus but the clypeus of the latter is almost as wide as the face while the clypeus of M. cis is narrow. Also the malar space (shorter than mandibular base on M. breviantennatus, as wide as mandibular base on M. cis) and the face (slightly more transverse face in M. brevianennatus, round face in M. cis) should separate these species.
 Studied material: ~ 20 specimens.
 Description: Size about 2.5–3.5mm. Antennae 20–22 articles. Head rounded behind eyes. Ocelli small, OOL=3. Eyes small, not strongly protuberant, slightly convergent. Malar space slightly shorter than basal breadth of mandible. Face 1.5–2.0 times as broad as high, smooth, punctate, not strongly protuberant. Clypeus narrower than face, almost flat, its apical border weakly notched medially and usually with a weak vertical impression behind the notch. Tentorial pits distinct. Mandibles short, stout and moderately twisted. Precoxal sulcus foveolate, sometimes broadening anteriorly. Mesopleuron dorsally reticulate-rugose, otherwise smoothly punctate. Propodeum with carinae with very weak rugose sculpture in between. Petiolar tergum with large distinct dorsal pits, dorsal surface generally reticulate-rugose with a few longitudinal striae laterally. Ovipositor about twice the length of petiolar tergum, slender. Legs slender; hind coxa never strongly rugose but often with a trace of obsolescent rugosity at the base and on the outer surface. Tarsal claws not lobed but somewhat swollen basally. Colour testaceous to brown; clypeus, mandibles and usually 3 rd abdominal tergite reddish testaceous; coxa and legs yellow. Pterostigma dark with light border around, more so anteriorly. Fore wing m-cu antefurcal, vein 2-SR+M almost as long as vein r, at most 0.7 times).
 Distribution: Palearctic. Country records: Austria; China; France; Germany; Ireland; Japan; Korea; Netherlands; Sweden; United Kingdom.
 Biology: Meteorus cis is recorded as a parasitoid of Cis boleti Scopoli, 1763 (Bouché 1834). We found 12 specimens within the SMTP; they were caught in both deciduous and coniferous forests. Flying time is from July to October.
description: Published as part of Stigenberg, Julia & Ronquist, Fredrik, 2011, Revision of the Western Palearctic Meteorini (Hymenoptera, Braconidae), with a molecular characterization of hidden Fennoscandian species diversity 3084, pp. 1-95 in Zootaxa 3084 (1) on page 50, DOI: 10.11646/zootaxa.3084.1.1, http://zenodo.org/record/5244448